PMCID	PMID	Name	Pattern	Credit	AllNames	inferredPLoS5	inferredCRediT	Inferred
5954787	29782574	DK	2	analyzed the study parameters from the clinical point of view	analyzed the study parameters from the clinical point of view	Analyzed the data	Formal analysis	YES
5954787	29782574	EJ	2	designed the study and drafted the manuscript	designed the study and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5954787	29782574	GK	2	designed of the study and drafted the manuscript|contributed equally to this work and share first authorship	designed of the study and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5954787	29782574	GK	2	designed of the study and drafted the manuscript|contributed equally to this work and share first authorship	contributed equally to this work and share first authorship	-	-	NO
5954787	29782574	GL	2	analyzed the study parameters and prepared the 3d printing phantom	analyzed the study parameters and prepared the 3d printing phantom	Analyzed the data	Formal analysis	YES
5954787	29782574	HS	2	supervised the preparation of the manuscript as a corresponding author|contributed equally to this work as corresponding authors	supervised the preparation of the manuscript as a corresponding author	Wrote the paper	Supervision|Writing - Original Draft	YES
5954787	29782574	HS	2	supervised the preparation of the manuscript as a corresponding author|contributed equally to this work as corresponding authors	contributed equally to this work as corresponding authors	-	-	NO
5954787	29782574	JP	2	also designed the study and performed the in vitro experiments|contributed equally to this work and share first authorship	also designed the study and performed the in vitro experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5954787	29782574	JP	2	also designed the study and performed the in vitro experiments|contributed equally to this work and share first authorship	contributed equally to this work and share first authorship	-	-	NO
5954787	29782574	JT	2	designed the study and drafted the manuscript	designed the study and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5954787	29782574	KK	2	performed the in vitro experiments	performed the in vitro experiments	Performed the experiments	Investigation	YES
5954787	29782574	NK	2	supervised the designing of the study as a corresponding author|contributed equally to this work as corresponding authors	supervised the designing of the study as a corresponding author	Conceived and designed the experiments	Methodology|Supervision	YES
5954787	29782574	NK	2	supervised the designing of the study as a corresponding author|contributed equally to this work as corresponding authors	contributed equally to this work as corresponding authors	-	-	NO
5954788	29782600	ASG	1	Provided technical expertise and methodology development|Assisted in writing and editing the manuscript	Provided technical expertise and methodology development	Performed the experiments	Methodology	YES
5954788	29782600	ASG	1	Provided technical expertise and methodology development|Assisted in writing and editing the manuscript	Assisted in writing and editing the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5954788	29782600	ASRM	1	Provided technical expertise and methodology development|Assisted in writing and editing the manuscript	Provided technical expertise and methodology development	Performed the experiments	Methodology	YES
5954788	29782600	ASRM	1	Provided technical expertise and methodology development|Assisted in writing and editing the manuscript	Assisted in writing and editing the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5954788	29782600	CC	1	Study design and conceptualization|Assisted in writing and editing the manuscript	Study design and conceptualization	Conceived and designed the experiments	Conceptualization|Methodology	YES
5954788	29782600	CC	1	Study design and conceptualization|Assisted in writing and editing the manuscript	Assisted in writing and editing the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5954788	29782600	CDF	1	Study design and conceptualization|Provided technical expertise and methodology development|Assisted in writing and editing the manuscript	Study design and conceptualization	Conceived and designed the experiments	Conceptualization|Methodology	YES
5954788	29782600	CDF	1	Study design and conceptualization|Provided technical expertise and methodology development|Assisted in writing and editing the manuscript	Provided technical expertise and methodology development	Performed the experiments	Methodology	YES
5954788	29782600	CDF	1	Study design and conceptualization|Provided technical expertise and methodology development|Assisted in writing and editing the manuscript	Assisted in writing and editing the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5954788	29782600	CW	1	Study design and conceptualization|Collection of data|Assisted in writing and editing the manuscript	Study design and conceptualization	Conceived and designed the experiments	Conceptualization|Methodology	YES
5954788	29782600	CW	1	Study design and conceptualization|Collection of data|Assisted in writing and editing the manuscript	Collection of data	Performed the experiments	Investigation	YES
5954788	29782600	CW	1	Study design and conceptualization|Collection of data|Assisted in writing and editing the manuscript	Assisted in writing and editing the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5954788	29782600	DIR	1	Study design and conceptualization|Provided technical expertise and methodology development|Assisted in writing and editing the manuscript	Study design and conceptualization	Conceived and designed the experiments	Conceptualization|Methodology	YES
5954788	29782600	DIR	1	Study design and conceptualization|Provided technical expertise and methodology development|Assisted in writing and editing the manuscript	Provided technical expertise and methodology development	Performed the experiments	Methodology	YES
5954788	29782600	DIR	1	Study design and conceptualization|Provided technical expertise and methodology development|Assisted in writing and editing the manuscript	Assisted in writing and editing the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5954788	29782600	EJK	1	Study design and conceptualization|Oversight and supervision of the research activities|Assisted in writing and editing the manuscript	Study design and conceptualization	Conceived and designed the experiments	Conceptualization|Methodology	YES
5954788	29782600	EJK	1	Study design and conceptualization|Oversight and supervision of the research activities|Assisted in writing and editing the manuscript	Oversight and supervision of the research activities	-	Supervision	YES
5954788	29782600	EJK	1	Study design and conceptualization|Oversight and supervision of the research activities|Assisted in writing and editing the manuscript	Assisted in writing and editing the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5954788	29782600	GBG	1	Provided technical expertise and methodology development|Assisted in writing and editing the manuscript	Provided technical expertise and methodology development	Performed the experiments	Methodology	YES
5954788	29782600	GBG	1	Provided technical expertise and methodology development|Assisted in writing and editing the manuscript	Assisted in writing and editing the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5954788	29782600	HS	1	Provided technical expertise and methodology development|Assisted in writing and editing the manuscript	Provided technical expertise and methodology development	Performed the experiments	Methodology	YES
5954788	29782600	HS	1	Provided technical expertise and methodology development|Assisted in writing and editing the manuscript	Assisted in writing and editing the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5954788	29782600	JP	1	Provided technical expertise and methodology development|Assisted in writing and editing the manuscript	Provided technical expertise and methodology development	Performed the experiments	Methodology	YES
5954788	29782600	JP	1	Provided technical expertise and methodology development|Assisted in writing and editing the manuscript	Assisted in writing and editing the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5954788	29782600	MSC	1	Study design and conceptualization|Provided technical expertise and methodology development|Assisted in writing and editing the manuscript	Study design and conceptualization	Conceived and designed the experiments	Conceptualization|Methodology	YES
5954788	29782600	MSC	1	Study design and conceptualization|Provided technical expertise and methodology development|Assisted in writing and editing the manuscript	Provided technical expertise and methodology development	Performed the experiments	Methodology	YES
5954788	29782600	MSC	1	Study design and conceptualization|Provided technical expertise and methodology development|Assisted in writing and editing the manuscript	Assisted in writing and editing the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5954788	29782600	MZ	1	Collection of data|Assisted in writing and editing the manuscript	Collection of data	Performed the experiments	Investigation	YES
5954788	29782600	MZ	1	Collection of data|Assisted in writing and editing the manuscript	Assisted in writing and editing the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5954788	29782600	SJF	1	Provided technical expertise and methodology development|Assisted in writing and editing the manuscript	Provided technical expertise and methodology development	Performed the experiments	Methodology	YES
5954788	29782600	SJF	1	Provided technical expertise and methodology development|Assisted in writing and editing the manuscript	Assisted in writing and editing the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5954788	29782600	WHM	1	Provided technical expertise and methodology development|Assisted in writing and editing the manuscript	Provided technical expertise and methodology development	Performed the experiments	Methodology	YES
5954788	29782600	WHM	1	Provided technical expertise and methodology development|Assisted in writing and editing the manuscript	Assisted in writing and editing the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5954789	29782603	DW	2	carried out the method design and development and critically revised the manuscript	carried out the method design and development and critically revised the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5954789	29782603	HL	2	conceived the cast design, carried out the clinical trial, and both drafted and edited the manuscript	conceived the cast design, carried out the clinical trial, and both drafted and edited the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5954789	29782603	LS	2	carried out data collection and analysis	carried out data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5954789	29782603	WH	2	conducted the clinical trial and critically revised the manuscript	conducted the clinical trial and critically revised the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5954789	29782603	XZ	2	carried out data collection and provided clinical advice	carried out data collection and provided clinical advice	Performed the experiments	Investigation	YES
5954789	29782603	YC	2	performed the clinical trial, designed the questionnaires and edited the manuscript	performed the clinical trial, designed the questionnaires and edited the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5954790	29782616	AA	2	performed the construction of the models and developed the workflow and critically reviewed and edited the manuscript	performed the construction of the models and developed the workflow and critically reviewed and edited the manuscript	Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5954790	29782616	CJ	2	critically reviewed and edited the manuscript	critically reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5954790	29782616	DJ	2	conceived of the project, performed the construction of the models and developed the workflow, authored and edited the manuscript	conceived of the project, performed the construction of the models and developed the workflow, authored and edited the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5954790	29782616	JM	2	conceived of the project and authored and edited the manuscript|conceived of the project, performed the construction of the models and developed the workflow, authored and edited the manuscript|performed the construction of the models and developed the workflow and edited the manuscript	conceived of the project and authored and edited the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
5954790	29782616	JM	2	conceived of the project and authored and edited the manuscript|conceived of the project, performed the construction of the models and developed the workflow, authored and edited the manuscript|performed the construction of the models and developed the workflow and edited the manuscript	conceived of the project, performed the construction of the models and developed the workflow, authored and edited the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5954790	29782616	JM	2	conceived of the project and authored and edited the manuscript|conceived of the project, performed the construction of the models and developed the workflow, authored and edited the manuscript|performed the construction of the models and developed the workflow and edited the manuscript	performed the construction of the models and developed the workflow and edited the manuscript	Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5954790	29782616	MM	2	conceived of the project, performed the construction of the models and developed the workflow, authored and edited the manuscript	conceived of the project, performed the construction of the models and developed the workflow, authored and edited the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5954790	29782616	RP	2	conceived of the project and critically reviewed and edited the manuscript	conceived of the project and critically reviewed and edited the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5954790	29782616	TO	2	critically reviewed and edited the manuscript	critically reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5954791	29782609	Every author	2	listed above has been actively involved in conceptual design, data collection, data analysis and interpretation, as well as manuscript drafting and editing	listed above has been actively involved in conceptual design, data collection, data analysis and interpretation, as well as manuscript drafting and editing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5954792	29782613	AC	2	interpreted the tensile testing data and helped with the manuscript	interpreted the tensile testing data and helped with the manuscript	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5954792	29782613	All authors	2	have read and have given final approval of the version to be published	have read and have given final approval of the version to be published	-	-	NO
5954792	29782613	CR	2	contributed significant portions of the manuscript|interpreted the tensile testing data and helped with the manuscript	contributed significant portions of the manuscript	-	-	NO
5954792	29782613	CR	2	contributed significant portions of the manuscript|interpreted the tensile testing data and helped with the manuscript	interpreted the tensile testing data and helped with the manuscript	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5954792	29782613	CT	2	scans of the patient, and converted this geometry into printable stl files	scans of the patient, and converted this geometry into printable stl files	-	-	NO
5954792	29782613	EM	2	contributed significant portions of the manuscript|interpreted the tensile testing data and helped with the manuscript	contributed significant portions of the manuscript	-	-	NO
5954792	29782613	EM	2	contributed significant portions of the manuscript|interpreted the tensile testing data and helped with the manuscript	interpreted the tensile testing data and helped with the manuscript	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5954792	29782613	MC	2	conceived the design, 3d printed the aneurysms, and analysed the data|drafted, edited and critically revised the manuscript|carried out the tensile strength tests|carried out data collection and analysis with the|interpreted the tensile testing data and helped with the manuscript	conceived the design, 3d printed the aneurysms, and analysed the data	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
5954792	29782613	MC	2	conceived the design, 3d printed the aneurysms, and analysed the data|drafted, edited and critically revised the manuscript|carried out the tensile strength tests|carried out data collection and analysis with the|interpreted the tensile testing data and helped with the manuscript	drafted, edited and critically revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5954792	29782613	MC	2	conceived the design, 3d printed the aneurysms, and analysed the data|drafted, edited and critically revised the manuscript|carried out the tensile strength tests|carried out data collection and analysis with the|interpreted the tensile testing data and helped with the manuscript	carried out the tensile strength tests	Performed the experiments	Investigation	YES
5954792	29782613	MC	2	conceived the design, 3d printed the aneurysms, and analysed the data|drafted, edited and critically revised the manuscript|carried out the tensile strength tests|carried out data collection and analysis with the|interpreted the tensile testing data and helped with the manuscript	carried out data collection and analysis with the	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5954792	29782613	MC	2	conceived the design, 3d printed the aneurysms, and analysed the data|drafted, edited and critically revised the manuscript|carried out the tensile strength tests|carried out data collection and analysis with the|interpreted the tensile testing data and helped with the manuscript	interpreted the tensile testing data and helped with the manuscript	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5954792	29782613	NC	2	provided the aneurysm scan of the patient	provided the aneurysm scan of the patient	-	-	NO
5954792	29782613	NR	2	drafted, edited and critically revised the manuscript|was the daily supervisor of the project|helped with the carried out data collection and analysis with the	drafted, edited and critically revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5954792	29782613	NR	2	drafted, edited and critically revised the manuscript|was the daily supervisor of the project|helped with the carried out data collection and analysis with the	was the daily supervisor of the project	-	Supervision	YES
5954792	29782613	NR	2	drafted, edited and critically revised the manuscript|was the daily supervisor of the project|helped with the carried out data collection and analysis with the	helped with the carried out data collection and analysis with the	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5954792	29782613	VK	2	provided the 3d printer and filaments, and guided the printing part|interpreted the tensile testing data and helped with the manuscript	provided the 3d printer and filaments, and guided the printing part	-	Supervision	YES
5954792	29782613	VK	2	provided the 3d printer and filaments, and guided the printing part|interpreted the tensile testing data and helped with the manuscript	interpreted the tensile testing data and helped with the manuscript	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5954793	29782619	AS	2	designed the course and wrote the manuscript	designed the course and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
5954793	29782619	All authors	2	contributed to the manuscript and tested manuscript contents|have reviewed and corrected the final manuscript	contributed to the manuscript and tested manuscript contents	Performed the experiments	Investigation	YES
5954793	29782619	All authors	2	contributed to the manuscript and tested manuscript contents|have reviewed and corrected the final manuscript	have reviewed and corrected the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5954793	29782619	LC	2	designed the course and wrote the manuscript	designed the course and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
5954794	29782615	HT	7	Study design, Methodology, Drafting and revision of manuscript	Study design, Methodology, Drafting and revision of manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5954794	29782615	JL	7	Scanner mount, Parametric modeling, Training formulation, Design exercise, Revision of manuscript	Scanner mount, Parametric modeling, Training formulation, Design exercise, Revision of manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
5954795	29782617	AAOC	2	supervised experimental execution and helped with data interpretation	supervised experimental execution and helped with data interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Supervision	YES
5954795	29782617	All authors	2	drafted the manuscript and approved the final version	drafted the manuscript and approved the final version	Wrote the paper	Writing - Original Draft	YES
5954795	29782617	CR	2	participated in the conception and design of the study, data analysis and interpretation	participated in the conception and design of the study, data analysis and interpretation	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
5954795	29782617	FWG	2	participated in the conception and design of the study, data analysis and interpretation|contributed equally to this work	participated in the conception and design of the study, data analysis and interpretation	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
5954795	29782617	FWG	2	participated in the conception and design of the study, data analysis and interpretation|contributed equally to this work	contributed equally to this work	-	-	NO
5954795	29782617	HRM	2	supervised experimental execution and helped with data interpretation	supervised experimental execution and helped with data interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Supervision	YES
5954795	29782617	OB	2	supervised experimental execution and helped with data interpretation	supervised experimental execution and helped with data interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Supervision	YES
5954795	29782617	RHM	2	participated in the conception and design of the study, data analysis and interpretation	participated in the conception and design of the study, data analysis and interpretation	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
5954795	29782617	TZP	2	participated in the conception and design of the study, data analysis and interpretation	participated in the conception and design of the study, data analysis and interpretation	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
5954795	29782617	VHS	2	participated in the conception and design of the study, data analysis and interpretation|contributed equally to this work	participated in the conception and design of the study, data analysis and interpretation	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
5954795	29782617	VHS	2	participated in the conception and design of the study, data analysis and interpretation|contributed equally to this work	contributed equally to this work	-	-	NO
5954796	29782607	All three authors	2	have made substantive intellectual contributions to the study	have made substantive intellectual contributions to the study	-	-	NO
5954797	29782614	AA	7	Study design, Data Acquisition, Critical revision of the manuscript	Study design, Data Acquisition, Critical revision of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
5954797	29782614	CHMcC	7	Study design, Critical revision of the manuscript	Study design, Critical revision of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5954797	29782614	JK	7	Study design, Critical revision of the manuscript	Study design, Critical revision of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5954797	29782614	JM	7	Study design, Data Acquisition, Critical revision of the manuscript|Study design, Data Acquisition, Drafting of manuscript, Critical revision of the manuscript	Study design, Data Acquisition, Critical revision of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
5954797	29782614	JM	7	Study design, Data Acquisition, Critical revision of the manuscript|Study design, Data Acquisition, Drafting of manuscript, Critical revision of the manuscript	Study design, Data Acquisition, Drafting of manuscript, Critical revision of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5954797	29782614	KMcG	7	Study design, Data Acquisition, Drafting of manuscript, Critical revision of the manuscript	Study design, Data Acquisition, Drafting of manuscript, Critical revision of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5954797	29782614	SL	7	Study design, Data Acquisition, Data Analysis, Drafting of manuscript, Critical revision of the manuscript	Study design, Data Acquisition, Data Analysis, Drafting of manuscript, Critical revision of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5954797	29782614	TV	7	Study design, Data Acquisition, Critical revision of the manuscript	Study design, Data Acquisition, Critical revision of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
5954799	29782611	JCSH	2	helped design the device, the culture setup, troubleshooting, and provided financial support	helped design the device, the culture setup, troubleshooting, and provided financial support	Conceived and designed the experiments|Performed the experiments	Funding acquisition|Investigation	YES
5954799	29782611	MOC	2	conceived and designed the 3d device, conducted culture experiments and analyzed the slides	conceived and designed the 3d device, conducted culture experiments and analyzed the slides	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation|Methodology	YES
5954799	29782611	RN	2	offered technical help throughout the experiments	offered technical help throughout the experiments	Performed the experiments	Investigation	YES
5970151	29882529	Both authors	2	have thoroughly read and approve of the final draft of the manuscript	have thoroughly read and approve of the final draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
6036601	30050976	DW	2	carried out the method design and development, edited and critically revised the manuscript	carried out the method design and development, edited and critically revised the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
6036601	30050976	HL	2	conceived the design, carried out the method development, drafted and edited manuscript	conceived the design, carried out the method development, drafted and edited manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
6036601	30050976	LS	2	carried out data collection and analysis, edited the manuscript	carried out data collection and analysis, edited the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
6036663	30050974	AS	7	contributed to test the replicas in clinical practice	contributed to test the replicas in clinical practice	-	-	NO
6036663	30050974	BM	7	contributed to test the replicas in clinical practice	contributed to test the replicas in clinical practice	-	-	NO
6036663	30050974	DR	7	contributed to prepare the study and write the manuscript	contributed to prepare the study and write the manuscript	Wrote the paper	Writing - Original Draft	YES
6036663	30050974	FF	7	contributed to create the models	contributed to create the models	Performed the experiments	Methodology	YES
6036663	30050974	GC	7	contributed to prepare the study and write the manuscript	contributed to prepare the study and write the manuscript	Wrote the paper	Writing - Original Draft	YES
6036663	30050974	IT	7	contributed to test the replicas in clinical practice	contributed to test the replicas in clinical practice	-	-	NO
6036663	30050974	NB	7	create the workflow to 3d print replicas of fractures	create the workflow to 3d print replicas of fractures	Performed the experiments	Methodology	YES
6036663	30050974	PP	7	Contributed to create the models with radiologist supervision	Contributed to create the models with radiologist supervision	Performed the experiments	Methodology|Supervision	YES
6036663	30050974	RA	7	contributed to test the replicas in clinical practice	contributed to test the replicas in clinical practice	-	-	NO
6036663	30050974	SF	7	contributed to create the models	contributed to create the models	Performed the experiments	Methodology	YES
6036666	30050982	AA	7	Study design, Data Acquisition, Critical revision of the manuscript	Study design, Data Acquisition, Critical revision of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
6036666	30050982	AH	7	Study design, Critical revision of the manuscript	Study design, Critical revision of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
6036666	30050982	CM	7	Study design, Critical revision of the manuscript	Study design, Critical revision of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
6036666	30050982	JF	7	Study design, Critical revision of the manuscript	Study design, Critical revision of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
6036666	30050982	JK	7	Study design, Data Acquisition, Critical revision of the manuscript	Study design, Data Acquisition, Critical revision of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
6036666	30050982	JM	7	Study design, Data Acquisition, Data Analysis, Critical revision of the manuscript|Study design, Critical revision of the manuscript	Study design, Data Acquisition, Data Analysis, Critical revision of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Review & Editing	YES
6036666	30050982	JM	7	Study design, Data Acquisition, Data Analysis, Critical revision of the manuscript|Study design, Critical revision of the manuscript	Study design, Critical revision of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
6036666	30050982	RM	7	Study design, Data Acquisition, Data Analysis, Drafting of manuscript, Critical revision of the manuscript	Study design, Data Acquisition, Data Analysis, Drafting of manuscript, Critical revision of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
6036666	30050982	SL	7	Study design, Data Acquisition, Data Analysis, Drafting of manuscript, Critical revision of the manuscript	Study design, Data Acquisition, Data Analysis, Drafting of manuscript, Critical revision of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
6036764	30050979	All the authors	2	helped to develop the methodology outlined in this report	helped to develop the methodology outlined in this report	Performed the experiments	Methodology	YES
6036764	30050979	BLC	2	helped refine the methodology to its current form, helped make some of the models discussed in this paper, made the figures and wrote the original manuscript	helped refine the methodology to its current form, helped make some of the models discussed in this paper, made the figures and wrote the original manuscript	Performed the experiments|Wrote the paper	Methodology|Visualization|Writing - Original Draft	YES
6036764	30050979	IR	2	helped develop the original methodology and helped make some of the models	helped develop the original methodology and helped make some of the models	Performed the experiments	Methodology	YES
6036764	30050979	JK	2	developed the original methodology and made the first model	developed the original methodology and made the first model	Performed the experiments	Methodology	YES
6036764	30050979	KWE	2	both advised the authors throughout the duration of this project and during the preparation of this manuscript	both advised the authors throughout the duration of this project and during the preparation of this manuscript	Wrote the paper	Writing - Original Draft	YES
6036764	30050979	NS	2	helped refine the methodology to its current form, helped make some of the models discussed in this paper and helped with preparing the original manuscript	helped refine the methodology to its current form, helped make some of the models discussed in this paper and helped with preparing the original manuscript	Performed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
6036764	30050979	TRM	2	both advised the authors throughout the duration of this project and during the preparation of this manuscript	both advised the authors throughout the duration of this project and during the preparation of this manuscript	Wrote the paper	Writing - Original Draft	YES
6036766	30050981	AG	2	conceived the study and drafted study outline|interpreted the data and drafted the manuscript	conceived the study and drafted study outline	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
6036766	30050981	AG	2	conceived the study and drafted study outline|interpreted the data and drafted the manuscript	interpreted the data and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6036766	30050981	AT	2	collected the requisite data|interpreted the data and drafted the manuscript	collected the requisite data	Performed the experiments	Investigation	YES
6036766	30050981	AT	2	collected the requisite data|interpreted the data and drafted the manuscript	interpreted the data and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6036766	30050981	All authors	2	have read and have given final approval of the version to be published	have read and have given final approval of the version to be published	-	-	NO
6036766	30050981	DM	2	conceived the study and drafted study outline|interpreted the data and drafted the manuscript	conceived the study and drafted study outline	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
6036766	30050981	DM	2	conceived the study and drafted study outline|interpreted the data and drafted the manuscript	interpreted the data and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6036766	30050981	FR	2	conceived the study and drafted study outline|interpreted the data and drafted the manuscript	conceived the study and drafted study outline	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
6036766	30050981	FR	2	conceived the study and drafted study outline|interpreted the data and drafted the manuscript	interpreted the data and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6036766	30050981	LC	2	conceived the study and drafted study outline|implemented software and carried out the analyses|interpreted the data and drafted the manuscript	conceived the study and drafted study outline	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
6036766	30050981	LC	2	conceived the study and drafted study outline|implemented software and carried out the analyses|interpreted the data and drafted the manuscript	implemented software and carried out the analyses	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Software	YES
6036766	30050981	LC	2	conceived the study and drafted study outline|implemented software and carried out the analyses|interpreted the data and drafted the manuscript	interpreted the data and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6036767	30050977	AG	2	contributed significant portions of the manuscript|interpreted the data and drafted the manuscript	contributed significant portions of the manuscript	-	-	NO
6036767	30050977	AG	2	contributed significant portions of the manuscript|interpreted the data and drafted the manuscript	interpreted the data and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6036767	30050977	AS	2	conceived the design, analyzed the data, drafted, edited and critically revised the manuscript|interpreted the data and drafted the manuscript	conceived the design, analyzed the data, drafted, edited and critically revised the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
6036767	30050977	AS	2	conceived the design, analyzed the data, drafted, edited and critically revised the manuscript|interpreted the data and drafted the manuscript	interpreted the data and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6036767	30050977	AW	2	provided customized illustrations|interpreted the data and drafted the manuscript	provided customized illustrations	Analyzed the data	Visualization	YES
6036767	30050977	AW	2	provided customized illustrations|interpreted the data and drafted the manuscript	interpreted the data and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6036767	30050977	All authors	2	have read and have given final approval of the version to be published	have read and have given final approval of the version to be published	-	-	NO
6036767	30050977	CT	2	interpreted the data and drafted the manuscript	interpreted the data and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6036767	30050977	DM	2	interpreted the data and drafted the manuscript	interpreted the data and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6036767	30050977	EA	2	interpreted the data and drafted the manuscript	interpreted the data and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6036767	30050977	LC	2	conceived the design, analyzed the data, drafted, edited and critically revised the manuscript|carried out data collection and analysis|interpreted the data and drafted the manuscript	conceived the design, analyzed the data, drafted, edited and critically revised the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
6036767	30050977	LC	2	conceived the design, analyzed the data, drafted, edited and critically revised the manuscript|carried out data collection and analysis|interpreted the data and drafted the manuscript	carried out data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6036767	30050977	LC	2	conceived the design, analyzed the data, drafted, edited and critically revised the manuscript|carried out data collection and analysis|interpreted the data and drafted the manuscript	interpreted the data and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6036767	30050977	SK	2	interpreted the data and drafted the manuscript	interpreted the data and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6036767	30050977	TH	2	contributed significant portions of the manuscript	contributed significant portions of the manuscript	-	-	NO
6097791	30148203	HK	2	collected the requisite data|interpreted the data and drafted the manuscript	collected the requisite data	Performed the experiments	Investigation	YES
6097791	30148203	HK	2	collected the requisite data|interpreted the data and drafted the manuscript	interpreted the data and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6097791	30148203	TK	2	conceived the study and drafted study outline|implemented software and carried out the analyses|interpreted the data and drafted the manuscript	conceived the study and drafted study outline	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
6097791	30148203	TK	2	conceived the study and drafted study outline|implemented software and carried out the analyses|interpreted the data and drafted the manuscript	implemented software and carried out the analyses	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Software	YES
6097791	30148203	TK	2	conceived the study and drafted study outline|implemented software and carried out the analyses|interpreted the data and drafted the manuscript	interpreted the data and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6097791	30148203	TS	2	implemented software and carried out the analyses	implemented software and carried out the analyses	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Software	YES
6097791	30148203	TT	2	collected the requisite data|implemented software and carried out the analyses	collected the requisite data	Performed the experiments	Investigation	YES
6097791	30148203	TT	2	collected the requisite data|implemented software and carried out the analyses	implemented software and carried out the analyses	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Software	YES
6097791	30148203	YK	2	implemented software and carried out the analyses	implemented software and carried out the analyses	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Software	YES
6179970	30649653	DG	7	conducted training sessions; edited manuscript	conducted training sessions; edited manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
6179970	30649653	SA	7	conducted training sessions; edited manuscript	conducted training sessions; edited manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
6179970	30649653	VS	7	experimental design; conducted training sessions; edited manuscript	experimental design; conducted training sessions; edited manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
6179970	30649653	YL	7	experimental design; conducted training sessions; drafting manuscript	experimental design; conducted training sessions; drafting manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
6179970	30649653	ZL	7	conducted training sessions; edited manuscript	conducted training sessions; edited manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
6195498	30649649	BC	2	provided his lab space in agh to allow for testing using the six-degrees-of-freedom machine while offering feedback	provided his lab space in agh to allow for testing using the six-degrees-of-freedom machine while offering feedback	Performed the experiments	Investigation	YES
6195498	30649649	JH	2	collected, printed, and tested all specimens and samples, analyzed and collected all data, and wrote the entirety of the paper	collected, printed, and tested all specimens and samples, analyzed and collected all data, and wrote the entirety of the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6195498	30649649	MR	2	developed the code used to develop the stochastic framework mimicking trabecular bone in the 3d-printed models	developed the code used to develop the stochastic framework mimicking trabecular bone in the 3d-printed models	Performed the experiments	Methodology|Software	YES
6195498	30649649	YY	2	helped print the specimens, provided testing feedback, and experimental setup feedback while helping guide the project along	helped print the specimens, provided testing feedback, and experimental setup feedback while helping guide the project along	Performed the experiments	Investigation	YES
6197341	30649646	CJB	1	Design|Experiments|Analysis of data|Initial draft|Critical revisions	Design	Conceived and designed the experiments	-	YES
6197341	30649646	CJB	1	Design|Experiments|Analysis of data|Initial draft|Critical revisions	Experiments	-	-	NO
6197341	30649646	CJB	1	Design|Experiments|Analysis of data|Initial draft|Critical revisions	Analysis of data	Analyzed the data	Formal analysis	YES
6197341	30649646	CJB	1	Design|Experiments|Analysis of data|Initial draft|Critical revisions	Initial draft	Wrote the paper	Writing - Original Draft	YES
6197341	30649646	CJB	1	Design|Experiments|Analysis of data|Initial draft|Critical revisions	Critical revisions	Wrote the paper	Writing - Review & Editing	YES
6197341	30649646	DHB	1	Initial draft|Critical revisions	Initial draft	Wrote the paper	Writing - Original Draft	YES
6197341	30649646	DHB	1	Initial draft|Critical revisions	Critical revisions	Wrote the paper	Writing - Review & Editing	YES
6197341	30649646	GEG	1	Critical revisions	Critical revisions	Wrote the paper	Writing - Review & Editing	YES
6197341	30649646	JEW	1	Critical revisions	Critical revisions	Wrote the paper	Writing - Review & Editing	YES
6197341	30649646	JSA	1	Design|Experiments|Analysis of data|Guaranteer of study|Initial draft|Critical revisions	Design	Conceived and designed the experiments	-	YES
6197341	30649646	JSA	1	Design|Experiments|Analysis of data|Guaranteer of study|Initial draft|Critical revisions	Experiments	-	-	NO
6197341	30649646	JSA	1	Design|Experiments|Analysis of data|Guaranteer of study|Initial draft|Critical revisions	Analysis of data	Analyzed the data	Formal analysis	YES
6197341	30649646	JSA	1	Design|Experiments|Analysis of data|Guaranteer of study|Initial draft|Critical revisions	Guaranteer of study	-	-	NO
6197341	30649646	JSA	1	Design|Experiments|Analysis of data|Guaranteer of study|Initial draft|Critical revisions	Initial draft	Wrote the paper	Writing - Original Draft	YES
6197341	30649646	JSA	1	Design|Experiments|Analysis of data|Guaranteer of study|Initial draft|Critical revisions	Critical revisions	Wrote the paper	Writing - Review & Editing	YES
6197341	30649646	JWY	1	Experiments|Analysis of data|Initial draft	Experiments	-	-	NO
6197341	30649646	JWY	1	Experiments|Analysis of data|Initial draft	Analysis of data	Analyzed the data	Formal analysis	YES
6197341	30649646	JWY	1	Experiments|Analysis of data|Initial draft	Initial draft	Wrote the paper	Writing - Original Draft	YES
6197341	30649646	MB	1	Experiments|Experiments|Analysis of data|Analysis of data|Initial draft	Experiments	-	-	NO
6197341	30649646	MB	1	Experiments|Experiments|Analysis of data|Analysis of data|Initial draft	Experiments	-	-	NO
6197341	30649646	MB	1	Experiments|Experiments|Analysis of data|Analysis of data|Initial draft	Analysis of data	Analyzed the data	Formal analysis	YES
6197341	30649646	MB	1	Experiments|Experiments|Analysis of data|Analysis of data|Initial draft	Analysis of data	Analyzed the data	Formal analysis	YES
6197341	30649646	MB	1	Experiments|Experiments|Analysis of data|Analysis of data|Initial draft	Initial draft	Wrote the paper	Writing - Original Draft	YES
6223396	30649650	DV	2	participated in manuscript creation	participated in manuscript creation	-	-	NO
6223396	30649650	JN	2	participated in manuscript creation	participated in manuscript creation	-	-	NO
6223396	30649650	JP	2	participated in statistical analysis	participated in statistical analysis	Analyzed the data	Formal analysis	YES
6223396	30649650	JR	2	conceived study design and participated in statistical analysis, manuscript writing, and 3d model creation	conceived study design and participated in statistical analysis, manuscript writing, and 3d model creation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
6223396	30649650	RR	2	participated in methods improvement and design	participated in methods improvement and design	Conceived and designed the experiments|Performed the experiments	-	YES
6223396	30649650	SP	2	participated in manuscript creation	participated in manuscript creation	-	-	NO
6251945	30649688	All	2	primary authors edited, reviewed, and approved this manuscript|included special interest group member coauthors, listed in the acknowledgements section, were provided with the final manuscript for review and approved its publication	primary authors edited, reviewed, and approved this manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6251945	30649688	All	2	primary authors edited, reviewed, and approved this manuscript|included special interest group member coauthors, listed in the acknowledgements section, were provided with the final manuscript for review and approved its publication	included special interest group member coauthors, listed in the acknowledgements section, were provided with the final manuscript for review and approved its publication	Wrote the paper	Writing - Review & Editing	YES
6261090	30649645	PCL	2	participated in engineering software and manuscript writing	participated in engineering software and manuscript writing	Contributed reagents/materials/analysis tools|Wrote the paper	Software|Writing - Original Draft	YES
6261090	30649645	SP	2	performed the surgeries, created the 3d models and composed the manuscript	performed the surgeries, created the 3d models and composed the manuscript	Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
6283805	30649656	KAM	2	segmented the hearts into the 3d models	segmented the hearts into the 3d models	Performed the experiments	Methodology	YES
6283805	30649656	KM	2	drafted, edited, and revised the manuscript	drafted, edited, and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6283805	30649656	KMF	2	obtained the images|contributed portions of the manuscript	obtained the images	Analyzed the data	Visualization	YES
6283805	30649656	KMF	2	obtained the images|contributed portions of the manuscript	contributed portions of the manuscript	-	-	NO
6283805	30649656	KPU	2	animated the models and input them into the virtual reality environment|contributed portions of the manuscript	animated the models and input them into the virtual reality environment	Performed the experiments	Methodology	YES
6283805	30649656	KPU	2	animated the models and input them into the virtual reality environment|contributed portions of the manuscript	contributed portions of the manuscript	-	-	NO
6283805	30649656	MTB	2	reviewed the segmentation|drafted, edited, and revised the manuscript	reviewed the segmentation	-	-	NO
6283805	30649656	MTB	2	reviewed the segmentation|drafted, edited, and revised the manuscript	drafted, edited, and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6283811	30649673	All authors	1	Critical revisions|Approval of final manuscript	Critical revisions	Wrote the paper	Writing - Review & Editing	YES
6283811	30649673	All authors	1	Critical revisions|Approval of final manuscript	Approval of final manuscript	Wrote the paper	Writing - Review & Editing	YES
6283811	30649673	CJB	1	Analysis of data	Analysis of data	Analyzed the data	Formal analysis	YES
6283811	30649673	DHB	1	Design|Analysis of data|Guaranteer of study|Initial draft	Design	Conceived and designed the experiments	-	YES
6283811	30649673	DHB	1	Design|Analysis of data|Guaranteer of study|Initial draft	Analysis of data	Analyzed the data	Formal analysis	YES
6283811	30649673	DHB	1	Design|Analysis of data|Guaranteer of study|Initial draft	Guaranteer of study	-	-	NO
6283811	30649673	DHB	1	Design|Analysis of data|Guaranteer of study|Initial draft	Initial draft	Wrote the paper	Writing - Original Draft	YES
6283811	30649673	JAS	1	Design	Design	Conceived and designed the experiments	-	YES
6283811	30649673	JAW	1	Design	Design	Conceived and designed the experiments	-	YES
6283811	30649673	KT	1	Design|Experiments|Analysis of data	Design	Conceived and designed the experiments	-	YES
6283811	30649673	KT	1	Design|Experiments|Analysis of data	Experiments	-	-	NO
6283811	30649673	KT	1	Design|Experiments|Analysis of data	Analysis of data	Analyzed the data	Formal analysis	YES
6283811	30649673	PKW	1	Design|Analysis of data|Initial draft	Design	Conceived and designed the experiments	-	YES
6283811	30649673	PKW	1	Design|Analysis of data|Initial draft	Analysis of data	Analyzed the data	Formal analysis	YES
6283811	30649673	PKW	1	Design|Analysis of data|Initial draft	Initial draft	Wrote the paper	Writing - Original Draft	YES
6283811	30649673	UJ	1	Design|Experiments|Analysis of data|Initial draft	Design	Conceived and designed the experiments	-	YES
6283811	30649673	UJ	1	Design|Experiments|Analysis of data|Initial draft	Experiments	-	-	NO
6283811	30649673	UJ	1	Design|Experiments|Analysis of data|Initial draft	Analysis of data	Analyzed the data	Formal analysis	YES
6283811	30649673	UJ	1	Design|Experiments|Analysis of data|Initial draft	Initial draft	Wrote the paper	Writing - Original Draft	YES
4895974	27267200	AAA	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
4895974	27267200	HA	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
4895974	27267200	IV	PLoS52	analyzed the data|designed the study and supervised all aspects of the project	analyzed the data	Analyzed the data	Formal analysis	YES
4895974	27267200	IV	PLoS52	analyzed the data|designed the study and supervised all aspects of the project	designed the study and supervised all aspects of the project	Conceived and designed the experiments	Methodology|Supervision	YES
4895974	27267200	LN	PLoS52	processed the brain and rna samples	processed the brain and rna samples	Analyzed the data	Data curation	YES
4895974	27267200	PL	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
4895974	27267200	RJE	PLoS52	supervised data analysis	supervised data analysis	Analyzed the data	Formal analysis|Supervision	YES
4895974	27267200	TGA	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
4895974	27267200	ZF	PLoS52	processed the brain and rna samples	processed the brain and rna samples	Analyzed the data	Data curation	YES
4897865	27267368	CGA	PLoS52	performed the experiments|analysed the data|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
4897865	27267368	CGA	PLoS52	performed the experiments|analysed the data|wrote the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
4897865	27267368	CGA	PLoS52	performed the experiments|analysed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4897865	27267368	JC	PLoS52	analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
4897865	27267368	LP	PLoS52	analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
4897865	27267368	MAA	PLoS52	conceived the study|wrote the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4897865	27267368	MAA	PLoS52	conceived the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4897865	27267368	MASP	PLoS52	conceived the study|wrote the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4897865	27267368	MASP	PLoS52	conceived the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4898365	27277524	AWW	2	designed studies|participated in analysis of 16s rrna gene and qpcr data|drafted the manuscript	designed studies	Conceived and designed the experiments	Methodology	YES
4898365	27277524	AWW	2	designed studies|participated in analysis of 16s rrna gene and qpcr data|drafted the manuscript	participated in analysis of 16s rrna gene and qpcr data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4898365	27277524	AWW	2	designed studies|participated in analysis of 16s rrna gene and qpcr data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4898365	27277524	BRL	2	participated in analysis of 16s rrna gene and qpcr data	participated in analysis of 16s rrna gene and qpcr data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4898365	27277524	CH	2	designed and carried out the clinical trial and clinical data collection|approved final document	designed and carried out the clinical trial and clinical data collection	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4898365	27277524	CH	2	designed and carried out the clinical trial and clinical data collection|approved final document	approved final document	-	-	NO
4898365	27277524	DAS	2	designed and carried out the clinical trial and clinical data collection|designed studies|drafted the manuscript	designed and carried out the clinical trial and clinical data collection	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4898365	27277524	DAS	2	designed and carried out the clinical trial and clinical data collection|designed studies|drafted the manuscript	designed studies	Conceived and designed the experiments	Methodology	YES
4898365	27277524	DAS	2	designed and carried out the clinical trial and clinical data collection|designed studies|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4898365	27277524	HCB	2	participated in analysis of 16s rrna gene and qpcr data	participated in analysis of 16s rrna gene and qpcr data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4898365	27277524	IA	2	participated in analysis of 16s rrna gene and qpcr data|drafted the manuscript	participated in analysis of 16s rrna gene and qpcr data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4898365	27277524	IA	2	participated in analysis of 16s rrna gene and qpcr data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4898365	27277524	JNP	2	participated in analysis of 16s rrna gene and qpcr data|drafted the manuscript	participated in analysis of 16s rrna gene and qpcr data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4898365	27277524	JNP	2	participated in analysis of 16s rrna gene and qpcr data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4898365	27277524	JP	2	designed studies|drafted the manuscript	designed studies	Conceived and designed the experiments	Methodology	YES
4898365	27277524	JP	2	designed studies|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4898365	27277524	MP	2	designed studies|participated in analysis of 16s rrna gene and qpcr data|drafted the manuscript	designed studies	Conceived and designed the experiments	Methodology	YES
4898365	27277524	MP	2	designed studies|participated in analysis of 16s rrna gene and qpcr data|drafted the manuscript	participated in analysis of 16s rrna gene and qpcr data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4898365	27277524	MP	2	designed studies|participated in analysis of 16s rrna gene and qpcr data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4898365	27277524	OCS	2	designed studies|participated in analysis of 16s rrna gene and qpcr data|drafted the manuscript	designed studies	Conceived and designed the experiments	Methodology	YES
4898365	27277524	OCS	2	designed studies|participated in analysis of 16s rrna gene and qpcr data|drafted the manuscript	participated in analysis of 16s rrna gene and qpcr data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4898365	27277524	OCS	2	designed studies|participated in analysis of 16s rrna gene and qpcr data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4898365	27277524	RIW	2	designed and carried out the clinical trial and clinical data collection	designed and carried out the clinical trial and clinical data collection	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4898365	27277524	SC	2	designed and carried out the clinical trial and clinical data collection|drafted the manuscript	designed and carried out the clinical trial and clinical data collection	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4898365	27277524	SC	2	designed and carried out the clinical trial and clinical data collection|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4898365	27277524	SL	2	collected molecular genetic data	collected molecular genetic data	Performed the experiments	Investigation	YES
4898393	27277319	BA	2	was involved in sequence analysis	was involved in sequence analysis	Performed the experiments	Investigation	YES
4898393	27277319	GMJ	2	carried out the research and wrote the manuscript	carried out the research and wrote the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4898393	27277319	JCM	2	participated in study design, provided input on analysis and revised the manuscript	participated in study design, provided input on analysis and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
4898393	27277319	JWK	2	provided access to data and revised the manuscript	provided access to data and revised the manuscript	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Review & Editing	YES
4898393	27277319	KGD	2	consulted on statistical analysis	consulted on statistical analysis	Analyzed the data	Formal analysis	YES
4898393	27277319	MAB	2	participated in study design, provided input on analysis and revised the manuscript	participated in study design, provided input on analysis and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
4898393	27277319	MEG	2	participated in study design, provided input on analysis and revised the manuscript	participated in study design, provided input on analysis and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
4898393	27277319	NC	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4899892	27277198	ASS	2	conceived the study, participated in the study design, managed the overall collaboration and helped to draft the manuscript	conceived the study, participated in the study design, managed the overall collaboration and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
4899892	27277198	DL	2	did the quality control and preliminary analysis	did the quality control and preliminary analysis	Performed the experiments	Validation	YES
4899892	27277198	GW	2	performed library construction and sequencing	performed library construction and sequencing	Performed the experiments	Investigation	YES
4899892	27277198	HJD	2	conceived the study, participated in the study design, managed the overall collaboration and helped to draft the manuscript	conceived the study, participated in the study design, managed the overall collaboration and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
4899892	27277198	JM	2	participated in the study design and helped to draft the manuscript	participated in the study design and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4899892	27277198	JS	2	conceived the study, participated in the study design, managed the overall collaboration and helped to draft the manuscript	conceived the study, participated in the study design, managed the overall collaboration and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
4899892	27277198	MBHT	2	analyzed cell cycle distribution	analyzed cell cycle distribution	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4899892	27277198	NB	2	conceived the study, participated in the study design, managed the overall collaboration and helped to draft the manuscript	conceived the study, participated in the study design, managed the overall collaboration and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
4899892	27277198	NSE	2	drafted the manuscript, performed exome sequence analysis, network analysis and prioritized variants	drafted the manuscript, performed exome sequence analysis, network analysis and prioritized variants	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4899892	27277198	RG	2	conceived the study, participated in the study design, managed the overall collaboration and helped to draft the manuscript	conceived the study, participated in the study design, managed the overall collaboration and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
4899892	27277198	RN	2	performed the enrichment analyses	performed the enrichment analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4899892	27277198	SNH	2	established the in vitro model system and helped to draft the manuscript	established the in vitro model system and helped to draft the manuscript	Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
4899892	27277198	SZ	2	did the quality control and preliminary analysis	did the quality control and preliminary analysis	Performed the experiments	Validation	YES
4899892	27277198	YH	2	did the quality control and preliminary analysis	did the quality control and preliminary analysis	Performed the experiments	Validation	YES
4901478	27286809	AD	2	designed the study, helped interpreting the results and critically reviewed the manuscript	designed the study, helped interpreting the results and critically reviewed the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
4901478	27286809	AGU	2	designed the study and critically reviewed the manuscript	designed the study and critically reviewed the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
4901478	27286809	AH	2	designed the study and critically reviewed the manuscript	designed the study and critically reviewed the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
4901478	27286809	AV	2	analyzed the lifelines cohort data and contributed to the manuscript writing	analyzed the lifelines cohort data and contributed to the manuscript writing	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4901478	27286809	BZA	2	designed the study and critically reviewed the manuscript	designed the study and critically reviewed the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
4901478	27286809	OHF	2	designed the study and critically reviewed the manuscript	designed the study and critically reviewed the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
4901478	27286809	RS	2	designed the study and critically reviewed the manuscript	designed the study and critically reviewed the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
4901478	27286809	SL	2	carried out the pleiotropy analyses, the replication analyses in the rotterdam cohorts and drafted the manuscript	carried out the pleiotropy analyses, the replication analyses in the rotterdam cohorts and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Validation|Writing - Original Draft	YES
4901478	27286809	YHH	2	developed the pleiotropy method, created the software and helped interpreting the results	developed the pleiotropy method, created the software and helped interpreting the results	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Methodology|Software	YES
4697910	28330075	The other authors	2	read, reviewed and provided feedback on the final manuscript	read, reviewed and provided feedback on the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4697910	28330075	Vo Van Giau	2	collected the samples, performed the experiments, analyzed and interpreted the data and wrote the manuscript	collected the samples, performed the experiments, analyzed and interpreted the data and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4902969	27286959	AG	2	constructed the pipeline for super-scaffolding	constructed the pipeline for super-scaffolding	Performed the experiments	Investigation	YES
4902969	27286959	AML	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
4902969	27286959	BA	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
4902969	27286959	CEH	2	identified nr5a1 as a candidate master sex determining gene	identified nr5a1 as a candidate master sex determining gene	Performed the experiments	Investigation	YES
4902969	27286959	HSBs	2	for unmapped super-scaffolds	for unmapped super-scaffolds	-	-	NO
4902969	27286959	JED	2	for unmapped super-scaffolds|performed experiments|constructed the comparative cytogenetic maps and analysed data for ancestral karyotype reconstructions|identified nr5a1 as a candidate master sex determining gene	for unmapped super-scaffolds	-	-	NO
4902969	27286959	JED	2	for unmapped super-scaffolds|performed experiments|constructed the comparative cytogenetic maps and analysed data for ancestral karyotype reconstructions|identified nr5a1 as a candidate master sex determining gene	performed experiments	Performed the experiments	Investigation	YES
4902969	27286959	JED	2	for unmapped super-scaffolds|performed experiments|constructed the comparative cytogenetic maps and analysed data for ancestral karyotype reconstructions|identified nr5a1 as a candidate master sex determining gene	constructed the comparative cytogenetic maps and analysed data for ancestral karyotype reconstructions	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4902969	27286959	JED	2	for unmapped super-scaffolds|performed experiments|constructed the comparative cytogenetic maps and analysed data for ancestral karyotype reconstructions|identified nr5a1 as a candidate master sex determining gene	identified nr5a1 as a candidate master sex determining gene	Performed the experiments	Investigation	YES
4902969	27286959	JL	2	constructed the pipeline for super-scaffolding	constructed the pipeline for super-scaffolding	Performed the experiments	Investigation	YES
4902969	27286959	MJE	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
4902969	27286959	QL	2	constructed the pipeline for super-scaffolding	constructed the pipeline for super-scaffolding	Performed the experiments	Investigation	YES
4902969	27286959	RS	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
4902969	27286959	SR	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
4902974	27287040	AS	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
4902974	27287040	JW	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
4902974	27287040	JZ	PLoS52	conceived the study and designed the experiments|carried out the experiments|analyzed the data|wrote the manuscript	conceived the study and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4902974	27287040	JZ	PLoS52	conceived the study and designed the experiments|carried out the experiments|analyzed the data|wrote the manuscript	carried out the experiments	Performed the experiments	Investigation	YES
4902974	27287040	JZ	PLoS52	conceived the study and designed the experiments|carried out the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
4902974	27287040	JZ	PLoS52	conceived the study and designed the experiments|carried out the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4902974	27287040	LL	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
4902974	27287040	LZ	PLoS52	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
4902974	27287040	QY	PLoS52	carried out the experiments|analyzed the data	carried out the experiments	Performed the experiments	Investigation	YES
4902974	27287040	QY	PLoS52	carried out the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
4902974	27287040	RM	PLoS52	conceived the study and designed the experiments|wrote the manuscript	conceived the study and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4902974	27287040	RM	PLoS52	conceived the study and designed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4902974	27287040	XZ	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
4902974	27287040	YC	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
4902995	27286864	All authors	2	read, edited and approved the manuscript	read, edited and approved the manuscript	Wrote the paper	Writing - Review & Editing	YES
4902995	27286864	CP	2	advised on bioinformatics and interpretation of data	advised on bioinformatics and interpretation of data	Analyzed the data	Formal analysis	YES
4902995	27286864	DJP	2	conceived and designed the study, advised on interpretation of the data	conceived and designed the study, advised on interpretation of the data	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
4902995	27286864	JBT	2	conceived and designed the molecular genomics component of the study, played the lead role in preparing the libraries and genotyping of ddrad alleles, designed the allele-specific pcr assays and was involved in data interpretation	conceived and designed the molecular genomics component of the study, played the lead role in preparing the libraries and genotyping of ddrad alleles, designed the allele-specific pcr assays and was involved in data interpretation	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation|Methodology	YES
4902995	27286864	JKB	2	extracted and purified the genomic dna, performed the restriction enzyme digests, assisted in preparation of the libraries and genotyping of ddrad alleles, generated the genetic linkage maps, performed the association analysis, verified the allele-specific pcr assays, analysed and interpreted the data and drafted the initial manuscript	extracted and purified the genomic dna, performed the restriction enzyme digests, assisted in preparation of the libraries and genotyping of ddrad alleles, generated the genetic linkage maps, performed the association analysis, verified the allele-specific pcr assays, analysed and interpreted the data and drafted the initial manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Validation|Writing - Original Draft	YES
4902995	27286864	MB	2	performed extra bioinformatics analyses, advised on interpretation of the data and on bioinformatics	performed extra bioinformatics analyses, advised on interpretation of the data and on bioinformatics	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4902995	27286864	NIWA	2	provided the fin clips	provided the fin clips	-	-	NO
4902995	27286864	SW	2	performed the comparative genomics and advised on bioinformatics	performed the comparative genomics and advised on bioinformatics	Performed the experiments	Formal analysis|Investigation	YES
4906602	27296049	MP	2	conceived the study and designed experiments|wrote the manuscript and approved its final version	conceived the study and designed experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4906602	27296049	MP	2	conceived the study and designed experiments|wrote the manuscript and approved its final version	wrote the manuscript and approved its final version	Wrote the paper	Writing - Original Draft	YES
4906602	27296049	RDH	2	conceived the study and designed experiments|carried out experiments and data analyses|wrote the manuscript and approved its final version	conceived the study and designed experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4906602	27296049	RDH	2	conceived the study and designed experiments|carried out experiments and data analyses|wrote the manuscript and approved its final version	carried out experiments and data analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4906602	27296049	RDH	2	conceived the study and designed experiments|carried out experiments and data analyses|wrote the manuscript and approved its final version	wrote the manuscript and approved its final version	Wrote the paper	Writing - Original Draft	YES
4906609	27296384	AY	2	performed the experiments and wrote the manuscript	performed the experiments and wrote the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4906609	27296384	HS	2	were involved in one or more processes of material culture, samples collection, data analysis and manuscript preparation	were involved in one or more processes of material culture, samples collection, data analysis and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Formal analysis|Investigation|Writing - Original Draft	YES
4906609	27296384	JJ	2	were involved in one or more processes of material culture, samples collection, data analysis and manuscript preparation	were involved in one or more processes of material culture, samples collection, data analysis and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Formal analysis|Investigation|Writing - Original Draft	YES
4906609	27296384	SG	2	were involved in one or more processes of material culture, samples collection, data analysis and manuscript preparation	were involved in one or more processes of material culture, samples collection, data analysis and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Formal analysis|Investigation|Writing - Original Draft	YES
4906609	27296384	XG	2	were involved in one or more processes of material culture, samples collection, data analysis and manuscript preparation	were involved in one or more processes of material culture, samples collection, data analysis and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Formal analysis|Investigation|Writing - Original Draft	YES
4906609	27296384	YD	2	were involved in one or more processes of material culture, samples collection, data analysis and manuscript preparation	were involved in one or more processes of material culture, samples collection, data analysis and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Formal analysis|Investigation|Writing - Original Draft	YES
4906609	27296384	YP	2	conducted the data analysis	conducted the data analysis	Analyzed the data	Formal analysis	YES
4906609	27296384	ZC	2	were involved in one or more processes of material culture, samples collection, data analysis and manuscript preparation	were involved in one or more processes of material culture, samples collection, data analysis and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Formal analysis|Investigation|Writing - Original Draft	YES
4906609	27296384	ZZ	2	conceived the experiments and corrected the manuscript	conceived the experiments and corrected the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
4906610	27297071	ALPC	2	collected the bacterial isolates and clinical information	collected the bacterial isolates and clinical information	Performed the experiments	Investigation	YES
4906610	27297071	All authors	2	contributed and approved the final manuscript	contributed and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4906610	27297071	BSPA	2	collected the bacterial isolates and clinical information	collected the bacterial isolates and clinical information	Performed the experiments	Investigation	YES
4906610	27297071	DCBL	2	collected the bacterial isolates and clinical information	collected the bacterial isolates and clinical information	Performed the experiments	Investigation	YES
4906610	27297071	E.L.T.	2	performed the phenotypic assays	performed the phenotypic assays	Performed the experiments	Investigation	YES
4906610	27297071	EX	2	designed and performed the bioinformatics analysis|interpreted the results and wrote the manuscript|contributed equally to the manuscript	designed and performed the bioinformatics analysis	Conceived and designed the experiments|Performed the experiments	Formal analysis|Investigation	YES
4906610	27297071	EX	2	designed and performed the bioinformatics analysis|interpreted the results and wrote the manuscript|contributed equally to the manuscript	interpreted the results and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4906610	27297071	EX	2	designed and performed the bioinformatics analysis|interpreted the results and wrote the manuscript|contributed equally to the manuscript	contributed equally to the manuscript	-	-	NO
4906610	27297071	KM	2	conceived the project|collected the bacterial isolates and clinical information|contributed equally to the manuscript	conceived the project	Conceived and designed the experiments	Conceptualization	YES
4906610	27297071	KM	2	conceived the project|collected the bacterial isolates and clinical information|contributed equally to the manuscript	collected the bacterial isolates and clinical information	Performed the experiments	Investigation	YES
4906610	27297071	KM	2	conceived the project|collected the bacterial isolates and clinical information|contributed equally to the manuscript	contributed equally to the manuscript	-	-	NO
4906610	27297071	OTN	2	conceived the project|collected the bacterial isolates and clinical information|designed and performed the bioinformatics analysis|interpreted the results and wrote the manuscript	conceived the project	Conceived and designed the experiments	Conceptualization	YES
4906610	27297071	OTN	2	conceived the project|collected the bacterial isolates and clinical information|designed and performed the bioinformatics analysis|interpreted the results and wrote the manuscript	collected the bacterial isolates and clinical information	Performed the experiments	Investigation	YES
4906610	27297071	OTN	2	conceived the project|collected the bacterial isolates and clinical information|designed and performed the bioinformatics analysis|interpreted the results and wrote the manuscript	designed and performed the bioinformatics analysis	Conceived and designed the experiments|Performed the experiments	Formal analysis|Investigation	YES
4906610	27297071	OTN	2	conceived the project|collected the bacterial isolates and clinical information|designed and performed the bioinformatics analysis|interpreted the results and wrote the manuscript	interpreted the results and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4906610	27297071	PUK	2	collected the bacterial isolates and clinical information	collected the bacterial isolates and clinical information	Performed the experiments	Investigation	YES
4906610	27297071	RTO	2	designed and performed the bioinformatics analysis|interpreted the results and wrote the manuscript	designed and performed the bioinformatics analysis	Conceived and designed the experiments|Performed the experiments	Formal analysis|Investigation	YES
4906610	27297071	RTO	2	designed and performed the bioinformatics analysis|interpreted the results and wrote the manuscript	interpreted the results and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4906610	27297071	S.N.	2	performed the phenotypic assays	performed the phenotypic assays	Performed the experiments	Investigation	YES
4906610	27297071	WX	2	designed and performed the bioinformatics analysis	designed and performed the bioinformatics analysis	Conceived and designed the experiments|Performed the experiments	Formal analysis|Investigation	YES
4906610	27297071	WXK	2	conceived the project|designed and performed the whole genome sequencing|designed and performed the bioinformatics analysis|interpreted the results and wrote the manuscript|contributed equally to the manuscript	conceived the project	Conceived and designed the experiments	Conceptualization	YES
4906610	27297071	WXK	2	conceived the project|designed and performed the whole genome sequencing|designed and performed the bioinformatics analysis|interpreted the results and wrote the manuscript|contributed equally to the manuscript	designed and performed the whole genome sequencing	Conceived and designed the experiments|Performed the experiments	Investigation	YES
4906610	27297071	WXK	2	conceived the project|designed and performed the whole genome sequencing|designed and performed the bioinformatics analysis|interpreted the results and wrote the manuscript|contributed equally to the manuscript	designed and performed the bioinformatics analysis	Conceived and designed the experiments|Performed the experiments	Formal analysis|Investigation	YES
4906610	27297071	WXK	2	conceived the project|designed and performed the whole genome sequencing|designed and performed the bioinformatics analysis|interpreted the results and wrote the manuscript|contributed equally to the manuscript	interpreted the results and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4906610	27297071	WXK	2	conceived the project|designed and performed the whole genome sequencing|designed and performed the bioinformatics analysis|interpreted the results and wrote the manuscript|contributed equally to the manuscript	contributed equally to the manuscript	-	-	NO
4906610	27297071	YYT	2	designed and performed the bioinformatics analysis	designed and performed the bioinformatics analysis	Conceived and designed the experiments|Performed the experiments	Formal analysis|Investigation	YES
4363531	25821806	An Liu	2	contributed equally to this work	contributed equally to this work	-	-	NO
4363531	25821806	Lin Yuan	2	contributed equally to this work	contributed equally to this work	-	-	NO
4906846	27297323	LA	2	designed the ddpcr assay, carried out the ddpcr measurements, data analysis, sequencing experiments and wrote the manuscript	designed the ddpcr assay, carried out the ddpcr measurements, data analysis, sequencing experiments and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4906846	27297323	MQ	2	designed the study and helped to draft the manuscript	designed the study and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4906846	27297323	YG	2	performed the bioinformatic analysis	performed the bioinformatic analysis	Performed the experiments	Formal analysis|Investigation	YES
4906896	27295982	BS	PLoS52	performed linkage data analysis|wrote the paper	performed linkage data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4906896	27295982	BS	PLoS52	performed linkage data analysis|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4906896	27295982	EG	PLoS52	contributed resources	contributed resources	Contributed reagents/materials/analysis tools	Resources	YES
4906896	27295982	GCP	PLoS52	conceived the study|prepare the samples and conducted dna genotyping|generated the linkage maps|programmed ldg imputations and generated linkage disequilibrium calculations|analyzed segregation distortion|performed linkage data analysis|wrote the paper|prepared the final figures	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4906896	27295982	GCP	PLoS52	conceived the study|prepare the samples and conducted dna genotyping|generated the linkage maps|programmed ldg imputations and generated linkage disequilibrium calculations|analyzed segregation distortion|performed linkage data analysis|wrote the paper|prepared the final figures	prepare the samples and conducted dna genotyping	Performed the experiments	Investigation	YES
4906896	27295982	GCP	PLoS52	conceived the study|prepare the samples and conducted dna genotyping|generated the linkage maps|programmed ldg imputations and generated linkage disequilibrium calculations|analyzed segregation distortion|performed linkage data analysis|wrote the paper|prepared the final figures	generated the linkage maps	Performed the experiments	Investigation	YES
4906896	27295982	GCP	PLoS52	conceived the study|prepare the samples and conducted dna genotyping|generated the linkage maps|programmed ldg imputations and generated linkage disequilibrium calculations|analyzed segregation distortion|performed linkage data analysis|wrote the paper|prepared the final figures	programmed ldg imputations and generated linkage disequilibrium calculations	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Software	YES
4906896	27295982	GCP	PLoS52	conceived the study|prepare the samples and conducted dna genotyping|generated the linkage maps|programmed ldg imputations and generated linkage disequilibrium calculations|analyzed segregation distortion|performed linkage data analysis|wrote the paper|prepared the final figures	analyzed segregation distortion	Analyzed the data	Formal analysis	YES
4906896	27295982	GCP	PLoS52	conceived the study|prepare the samples and conducted dna genotyping|generated the linkage maps|programmed ldg imputations and generated linkage disequilibrium calculations|analyzed segregation distortion|performed linkage data analysis|wrote the paper|prepared the final figures	performed linkage data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4906896	27295982	GCP	PLoS52	conceived the study|prepare the samples and conducted dna genotyping|generated the linkage maps|programmed ldg imputations and generated linkage disequilibrium calculations|analyzed segregation distortion|performed linkage data analysis|wrote the paper|prepared the final figures	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4906896	27295982	GCP	PLoS52	conceived the study|prepare the samples and conducted dna genotyping|generated the linkage maps|programmed ldg imputations and generated linkage disequilibrium calculations|analyzed segregation distortion|performed linkage data analysis|wrote the paper|prepared the final figures	prepared the final figures	-	Visualization	YES
4906896	27295982	JD	PLoS52	performed linkage data analysis|wrote the paper	performed linkage data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4906896	27295982	JD	PLoS52	performed linkage data analysis|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4906896	27295982	JP	PLoS52	contributed resources|wrote the paper	contributed resources	Contributed reagents/materials/analysis tools	Resources	YES
4906896	27295982	JP	PLoS52	contributed resources|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4906896	27295982	JZ	PLoS52	conceived the study|supervised the research|wrote the paper	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4906896	27295982	JZ	PLoS52	conceived the study|supervised the research|wrote the paper	supervised the research	-	Supervision	YES
4906896	27295982	JZ	PLoS52	conceived the study|supervised the research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4906896	27295982	LDG	PLoS52	performed the synteny analysis|performed linkage data analysis|wrote the paper|prepared the final figures	performed the synteny analysis	Performed the experiments	Investigation	YES
4906896	27295982	LDG	PLoS52	performed the synteny analysis|performed linkage data analysis|wrote the paper|prepared the final figures	performed linkage data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4906896	27295982	LDG	PLoS52	performed the synteny analysis|performed linkage data analysis|wrote the paper|prepared the final figures	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4906896	27295982	LDG	PLoS52	performed the synteny analysis|performed linkage data analysis|wrote the paper|prepared the final figures	prepared the final figures	-	Visualization	YES
4906896	27295982	MHO	PLoS52	prepare the samples and conducted dna genotyping|generated the linkage maps	prepare the samples and conducted dna genotyping	Performed the experiments	Investigation	YES
4906896	27295982	MHO	PLoS52	prepare the samples and conducted dna genotyping|generated the linkage maps	generated the linkage maps	Performed the experiments	Investigation	YES
4906896	27295982	MI	PLoS52	supervised the research|analyzed segregation distortion|performed the synteny analysis|wrote the paper	supervised the research	-	Supervision	YES
4906896	27295982	MI	PLoS52	supervised the research|analyzed segregation distortion|performed the synteny analysis|wrote the paper	analyzed segregation distortion	Analyzed the data	Formal analysis	YES
4906896	27295982	MI	PLoS52	supervised the research|analyzed segregation distortion|performed the synteny analysis|wrote the paper	performed the synteny analysis	Performed the experiments	Investigation	YES
4906896	27295982	MI	PLoS52	supervised the research|analyzed segregation distortion|performed the synteny analysis|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4906896	27295982	NV	PLoS52	contributed resources|wrote the paper	contributed resources	Contributed reagents/materials/analysis tools	Resources	YES
4906896	27295982	NV	PLoS52	contributed resources|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4906896	27295982	SS	PLoS52	contributed resources|wrote the paper	contributed resources	Contributed reagents/materials/analysis tools	Resources	YES
4906896	27295982	SS	PLoS52	contributed resources|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4906896	27295982	WS	PLoS52	prepare the samples and conducted dna genotyping	prepare the samples and conducted dna genotyping	Performed the experiments	Investigation	YES
4907000	27297497	DMC	2	worked on the manuscript and supervised the work	worked on the manuscript and supervised the work	Performed the experiments	Supervision	YES
4907000	27297497	DVB	2	developed software	developed software	Contributed reagents/materials/analysis tools	Software	YES
4907000	27297497	EVP	2	prepared the cdna libraries and performed software testing	prepared the cdna libraries and performed software testing	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
4907000	27297497	IVZ	2	prepared the cdna libraries and performed software testing	prepared the cdna libraries and performed software testing	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
4907000	27297497	MI	2	prepared the cdna libraries and performed software testing	prepared the cdna libraries and performed software testing	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
4907000	27297497	MS	2	developed software|worked on the manuscript	developed software	Contributed reagents/materials/analysis tools	Software	YES
4907000	27297497	MS	2	developed software|worked on the manuscript	worked on the manuscript	Performed the experiments	-	YES
4907000	27297497	OVB	2	prepared the cdna libraries and performed software testing	prepared the cdna libraries and performed software testing	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
4907009	27296290	NI	PLoS52	conceived the study|developed computational strategies	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4907009	27296290	NI	PLoS52	conceived the study|developed computational strategies	developed computational strategies	-	Formal analysis	YES
4907009	27296290	PR	PLoS52	developed computational strategies|drafted and revised the manuscript	developed computational strategies	-	Formal analysis	YES
4907009	27296290	PR	PLoS52	developed computational strategies|drafted and revised the manuscript	drafted and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4907009	27296290	PZ	PLoS52	conceived the study|developed computational strategies|analyzed the data|mapped cell lines to tumor types|drafted and revised the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4907009	27296290	PZ	PLoS52	conceived the study|developed computational strategies|analyzed the data|mapped cell lines to tumor types|drafted and revised the manuscript	developed computational strategies	-	Formal analysis	YES
4907009	27296290	PZ	PLoS52	conceived the study|developed computational strategies|analyzed the data|mapped cell lines to tumor types|drafted and revised the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
4907009	27296290	PZ	PLoS52	conceived the study|developed computational strategies|analyzed the data|mapped cell lines to tumor types|drafted and revised the manuscript	mapped cell lines to tumor types	Performed the experiments	Investigation	YES
4907009	27296290	PZ	PLoS52	conceived the study|developed computational strategies|analyzed the data|mapped cell lines to tumor types|drafted and revised the manuscript	drafted and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4907009	27296290	ZZ	PLoS52	conceived the study|developed computational strategies|analyzed the data|mapped cell lines to tumor types|drafted and revised the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4907009	27296290	ZZ	PLoS52	conceived the study|developed computational strategies|analyzed the data|mapped cell lines to tumor types|drafted and revised the manuscript	developed computational strategies	-	Formal analysis	YES
4907009	27296290	ZZ	PLoS52	conceived the study|developed computational strategies|analyzed the data|mapped cell lines to tumor types|drafted and revised the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
4907009	27296290	ZZ	PLoS52	conceived the study|developed computational strategies|analyzed the data|mapped cell lines to tumor types|drafted and revised the manuscript	mapped cell lines to tumor types	Performed the experiments	Investigation	YES
4907009	27296290	ZZ	PLoS52	conceived the study|developed computational strategies|analyzed the data|mapped cell lines to tumor types|drafted and revised the manuscript	drafted and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4907016	27295951	AB	2	revised the draft and made contributions to the final manuscript	revised the draft and made contributions to the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4907016	27295951	CC	2	revised the draft and made contributions to the final manuscript	revised the draft and made contributions to the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4907016	27295951	EH	2	supervised the design and coordination of the study	supervised the design and coordination of the study	Conceived and designed the experiments	Methodology|Project administration|Supervision	YES
4907016	27295951	LR	2	revised the draft and made contributions to the final manuscript	revised the draft and made contributions to the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4907016	27295951	MW	2	supervised sc designed and performed the bioinformatic analysis under the|revised the draft and made contributions to the final manuscript	supervised sc designed and performed the bioinformatic analysis under the	Conceived and designed the experiments|Performed the experiments	Formal analysis|Investigation|Supervision	YES
4907016	27295951	MW	2	supervised sc designed and performed the bioinformatic analysis under the|revised the draft and made contributions to the final manuscript	revised the draft and made contributions to the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4907016	27295951	PC	2	revised the draft and made contributions to the final manuscript	revised the draft and made contributions to the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4907016	27295951	SC	2	designed and performed the bioinformatic analysis under the|drafted the manuscript	designed and performed the bioinformatic analysis under the	Conceived and designed the experiments|Performed the experiments	Formal analysis|Investigation	YES
4907016	27295951	SC	2	designed and performed the bioinformatic analysis under the|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4907016	27295951	SP	2	supervised the design and coordination of the study|revised the draft and made contributions to the final manuscript	supervised the design and coordination of the study	Conceived and designed the experiments	Methodology|Project administration|Supervision	YES
4907016	27295951	SP	2	supervised the design and coordination of the study|revised the draft and made contributions to the final manuscript	revised the draft and made contributions to the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4907049	27296936	CSM	2	conducted the mass spectrometry analysis	conducted the mass spectrometry analysis	Performed the experiments	Investigation	YES
4907049	27296936	FJH	2	wrote the manuscript with input from all authors	wrote the manuscript with input from all authors	Wrote the paper	Writing - Original Draft	YES
4907049	27296936	JTM	2	conducted the mass spectrometry analysis	conducted the mass spectrometry analysis	Performed the experiments	Investigation	YES
4907049	27296936	JWS	2	assisted with experiments	assisted with experiments	Performed the experiments	Investigation	YES
4907049	27296936	NMB	2	conducted most of the experiments	conducted most of the experiments	Performed the experiments	Investigation	YES
4907049	27296936	RSM	2	wrote the manuscript with input from all authors|provided bioinformatic advice and analysis	wrote the manuscript with input from all authors	Wrote the paper	Writing - Original Draft	YES
4907049	27296936	RSM	2	wrote the manuscript with input from all authors|provided bioinformatic advice and analysis	provided bioinformatic advice and analysis	-	Formal analysis	YES
4907049	27296936	ZCL	2	conducted the phylogenomic analysis	conducted the phylogenomic analysis	Performed the experiments	Investigation	YES
4363544	25821783	Fauziah Othman	2	designed and supervised the research	designed and supervised the research	Conceived and designed the experiments	Methodology|Supervision	YES
4363544	25821783	Ismaila Ahmed	2	harvested, propagated, and purified the virus samples	harvested, propagated, and purified the virus samples	Performed the experiments	Investigation	YES
4363544	25821783	Nizar Abd Manan	2	designed and supervised the research	designed and supervised the research	Conceived and designed the experiments	Methodology|Supervision	YES
4363544	25821783	Umar Ahmad	2	harvested, propagated, and purified the virus samples|performed the experiments, run the data analysis, and drafted the paper	harvested, propagated, and purified the virus samples	Performed the experiments	Investigation	YES
4363544	25821783	Umar Ahmad	2	harvested, propagated, and purified the virus samples|performed the experiments, run the data analysis, and drafted the paper	performed the experiments, run the data analysis, and drafted the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4363544	25821783	Yong Yoke Keong	2	designed and supervised the research	designed and supervised the research	Conceived and designed the experiments	Methodology|Supervision	YES
4907050	27301965	LD	2	analyzed the data and drafted the manuscript	analyzed the data and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4907050	27301965	QW	2	participated in the measurement of meat quality	participated in the measurement of meat quality	Performed the experiments	Investigation	YES
4907050	27301965	SX	2	discovered snps, made the manhattan plot and revised the paper	discovered snps, made the manhattan plot and revised the paper	Wrote the paper	Writing - Review & Editing	YES
4907050	27301965	ZW	2	designed the experiment and revised the paper	designed the experiment and revised the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
4363546	25821813	Guohua Huang	2	contributed equally to this work	contributed equally to this work	-	-	NO
4363546	25821813	Yin Lu	2	contributed equally to this work	contributed equally to this work	-	-	NO
4907077	27297173	ARC	1	Experimental design|Result interpretation|Manuscript preparation	Experimental design	Conceived and designed the experiments	Methodology	YES
4907077	27297173	ARC	1	Experimental design|Result interpretation|Manuscript preparation	Result interpretation	Analyzed the data	Formal analysis	YES
4907077	27297173	ARC	1	Experimental design|Result interpretation|Manuscript preparation	Manuscript preparation	Wrote the paper	Writing - Original Draft	YES
4907077	27297173	JMS	1	Experimental design|Genotyping and ngs data analysis|Result interpretation|Manuscript preparation	Experimental design	Conceived and designed the experiments	Methodology	YES
4907077	27297173	JMS	1	Experimental design|Genotyping and ngs data analysis|Result interpretation|Manuscript preparation	Genotyping and ngs data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4907077	27297173	JMS	1	Experimental design|Genotyping and ngs data analysis|Result interpretation|Manuscript preparation	Result interpretation	Analyzed the data	Formal analysis	YES
4907077	27297173	JMS	1	Experimental design|Genotyping and ngs data analysis|Result interpretation|Manuscript preparation	Manuscript preparation	Wrote the paper	Writing - Original Draft	YES
4907077	27297173	LCC	1	Genotyping and ngs data analysis	Genotyping and ngs data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4907077	27297173	MEBY	1	Experimental design|Genotyping and ngs data analysis|Result interpretation|Manuscript preparation	Experimental design	Conceived and designed the experiments	Methodology	YES
4907077	27297173	MEBY	1	Experimental design|Genotyping and ngs data analysis|Result interpretation|Manuscript preparation	Genotyping and ngs data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4907077	27297173	MEBY	1	Experimental design|Genotyping and ngs data analysis|Result interpretation|Manuscript preparation	Result interpretation	Analyzed the data	Formal analysis	YES
4907077	27297173	MEBY	1	Experimental design|Genotyping and ngs data analysis|Result interpretation|Manuscript preparation	Manuscript preparation	Wrote the paper	Writing - Original Draft	YES
4907077	27297173	PFG	1	Experimental design|Genotyping and ngs data analysis|Result interpretation|Manuscript preparation	Experimental design	Conceived and designed the experiments	Methodology	YES
4907077	27297173	PFG	1	Experimental design|Genotyping and ngs data analysis|Result interpretation|Manuscript preparation	Genotyping and ngs data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4907077	27297173	PFG	1	Experimental design|Genotyping and ngs data analysis|Result interpretation|Manuscript preparation	Result interpretation	Analyzed the data	Formal analysis	YES
4907077	27297173	PFG	1	Experimental design|Genotyping and ngs data analysis|Result interpretation|Manuscript preparation	Manuscript preparation	Wrote the paper	Writing - Original Draft	YES
4907077	27297173	SRP	1	Result interpretation	Result interpretation	Analyzed the data	Formal analysis	YES
4907080	27296167	AL	PLoS5	Performed the experiment|Analyzed the data|Contributed reagents/materials/analysis tools|Revised and edited the paper	Performed the experiment	Performed the experiments	Investigation	YES
4907080	27296167	AL	PLoS5	Performed the experiment|Analyzed the data|Contributed reagents/materials/analysis tools|Revised and edited the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4907080	27296167	AL	PLoS5	Performed the experiment|Analyzed the data|Contributed reagents/materials/analysis tools|Revised and edited the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4907080	27296167	AL	PLoS5	Performed the experiment|Analyzed the data|Contributed reagents/materials/analysis tools|Revised and edited the paper	Revised and edited the paper	Wrote the paper	Writing - Review & Editing	YES
4907080	27296167	EQ	PLoS5	Contributed reagents/materials/analysis tools|Revised and edited the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4907080	27296167	EQ	PLoS5	Contributed reagents/materials/analysis tools|Revised and edited the paper	Revised and edited the paper	Wrote the paper	Writing - Review & Editing	YES
4907080	27296167	FM	PLoS5	Analyzed the data|Revised and edited the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4907080	27296167	FM	PLoS5	Analyzed the data|Revised and edited the paper	Revised and edited the paper	Wrote the paper	Writing - Review & Editing	YES
4907080	27296167	IG	PLoS5	Conceived and designed the experiments|Performed the experiment|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Revised and edited the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4907080	27296167	IG	PLoS5	Conceived and designed the experiments|Performed the experiment|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Revised and edited the paper	Performed the experiment	Performed the experiments	Investigation	YES
4907080	27296167	IG	PLoS5	Conceived and designed the experiments|Performed the experiment|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Revised and edited the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4907080	27296167	IG	PLoS5	Conceived and designed the experiments|Performed the experiment|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Revised and edited the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4907080	27296167	IG	PLoS5	Conceived and designed the experiments|Performed the experiment|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Revised and edited the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4907080	27296167	IG	PLoS5	Conceived and designed the experiments|Performed the experiment|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Revised and edited the paper	Revised and edited the paper	Wrote the paper	Writing - Review & Editing	YES
4907080	27296167	JM	PLoS5	Performed the experiment|Analyzed the data|Contributed reagents/materials/analysis tools|Revised and edited the paper	Performed the experiment	Performed the experiments	Investigation	YES
4907080	27296167	JM	PLoS5	Performed the experiment|Analyzed the data|Contributed reagents/materials/analysis tools|Revised and edited the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4907080	27296167	JM	PLoS5	Performed the experiment|Analyzed the data|Contributed reagents/materials/analysis tools|Revised and edited the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4907080	27296167	JM	PLoS5	Performed the experiment|Analyzed the data|Contributed reagents/materials/analysis tools|Revised and edited the paper	Revised and edited the paper	Wrote the paper	Writing - Review & Editing	YES
4907080	27296167	MD	PLoS5	Contributed reagents/materials/analysis tools|Revised and edited the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4907080	27296167	MD	PLoS5	Contributed reagents/materials/analysis tools|Revised and edited the paper	Revised and edited the paper	Wrote the paper	Writing - Review & Editing	YES
4907080	27296167	MNB	PLoS5	Conceived and designed the experiments|Performed the experiment|Analyzed the data|Wrote the paper|Revised and edited the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4907080	27296167	MNB	PLoS5	Conceived and designed the experiments|Performed the experiment|Analyzed the data|Wrote the paper|Revised and edited the paper	Performed the experiment	Performed the experiments	Investigation	YES
4907080	27296167	MNB	PLoS5	Conceived and designed the experiments|Performed the experiment|Analyzed the data|Wrote the paper|Revised and edited the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4907080	27296167	MNB	PLoS5	Conceived and designed the experiments|Performed the experiment|Analyzed the data|Wrote the paper|Revised and edited the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4907080	27296167	MNB	PLoS5	Conceived and designed the experiments|Performed the experiment|Analyzed the data|Wrote the paper|Revised and edited the paper	Revised and edited the paper	Wrote the paper	Writing - Review & Editing	YES
4907080	27296167	SJK	PLoS5	Analyzed the data|Revised and edited the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4907080	27296167	SJK	PLoS5	Analyzed the data|Revised and edited the paper	Revised and edited the paper	Wrote the paper	Writing - Review & Editing	YES
4907080	27296167	SP	PLoS5	Analyzed the data|Revised and edited the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4907080	27296167	SP	PLoS5	Analyzed the data|Revised and edited the paper	Revised and edited the paper	Wrote the paper	Writing - Review & Editing	YES
4363553	25821794	All authors	2	read and approved the final paper	read and approved the final paper	-	-	NO
4363553	25821794	Hongxia Ding	2	organized the clinical experiment and revised the paper|contributed equally to this work	organized the clinical experiment and revised the paper	Wrote the paper	Writing - Review & Editing	YES
4363553	25821794	Hongxia Ding	2	organized the clinical experiment and revised the paper|contributed equally to this work	contributed equally to this work	-	-	NO
4363553	25821794	Ningling Zhang	2	organized the clinical experiment and revised the paper|contributed equally to this work	organized the clinical experiment and revised the paper	Wrote the paper	Writing - Review & Editing	YES
4363553	25821794	Ningling Zhang	2	organized the clinical experiment and revised the paper|contributed equally to this work	contributed equally to this work	-	-	NO
4363553	25821794	Pan Li	2	provided suggestions and comments as well as much help in revising the paper	provided suggestions and comments as well as much help in revising the paper	Wrote the paper	Writing - Review & Editing	YES
4363553	25821794	Rongchao Peng	2	organized the clinical experiment and revised the paper|contributed equally to this work	organized the clinical experiment and revised the paper	Wrote the paper	Writing - Review & Editing	YES
4363553	25821794	Rongchao Peng	2	organized the clinical experiment and revised the paper|contributed equally to this work	contributed equally to this work	-	-	NO
4363553	25821794	Xiaolin Zhou	2	developed the algorithm and drafted the paper	developed the algorithm and drafted the paper	Contributed reagents/materials/analysis tools|Wrote the paper	Software|Writing - Original Draft	YES
4908685	27301971	GM	PLoS52	conducted experimental validation experiments	conducted experimental validation experiments	Performed the experiments	Investigation|Validation	YES
4908685	27301971	KHB	PLoS52	contributed to the design of additional experiments	contributed to the design of additional experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4908685	27301971	NN	PLoS52	conceived the study|wrote the paper	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4908685	27301971	NN	PLoS52	conceived the study|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4908685	27301971	NR	PLoS52	conceived the study|wrote the paper	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4908685	27301971	NR	PLoS52	conceived the study|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4908685	27301971	NT	PLoS52	conducted experimental validation experiments	conducted experimental validation experiments	Performed the experiments	Investigation|Validation	YES
4908685	27301971	SWC	PLoS52	wrote the paper|performed the bioinformatic analysis	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4908685	27301971	SWC	PLoS52	wrote the paper|performed the bioinformatic analysis	performed the bioinformatic analysis	Performed the experiments	Formal analysis|Investigation	YES
4908685	27301971	TCC	PLoS52	conducted experimental validation experiments	conducted experimental validation experiments	Performed the experiments	Investigation|Validation	YES
4908710	27301885	AR	2	participated in the data analysis	participated in the data analysis	Analyzed the data	Formal analysis	YES
4908710	27301885	EJ	2	conceived of the study, participated in its design and helped to draft the manuscript	conceived of the study, participated in its design and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
4908710	27301885	JP	2	carried out the molecular studies, wrote and performed the data analysis pipeline, and wrote the manuscript	carried out the molecular studies, wrote and performed the data analysis pipeline, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4908710	27301885	MR	2	participated in the data analysis	participated in the data analysis	Analyzed the data	Formal analysis	YES
4908840	27301979	AB	2	contributed to study concept and design|performed the statistical analysis|interpreted the data|participated in the drafting and critical revision of the manuscript	contributed to study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4908840	27301979	AB	2	contributed to study concept and design|performed the statistical analysis|interpreted the data|participated in the drafting and critical revision of the manuscript	performed the statistical analysis	Analyzed the data	Formal analysis	YES
4908840	27301979	AB	2	contributed to study concept and design|performed the statistical analysis|interpreted the data|participated in the drafting and critical revision of the manuscript	interpreted the data	Analyzed the data	Formal analysis	YES
4908840	27301979	AB	2	contributed to study concept and design|performed the statistical analysis|interpreted the data|participated in the drafting and critical revision of the manuscript	participated in the drafting and critical revision of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4908840	27301979	CM	2	participated in the sample and data collection|participated in the drafting and critical revision of the manuscript	participated in the sample and data collection	Performed the experiments	Investigation	YES
4908840	27301979	CM	2	participated in the sample and data collection|participated in the drafting and critical revision of the manuscript	participated in the drafting and critical revision of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4908840	27301979	HBS	2	contributed to study concept and design|interpreted the data|participated in the drafting and critical revision of the manuscript	contributed to study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4908840	27301979	HBS	2	contributed to study concept and design|interpreted the data|participated in the drafting and critical revision of the manuscript	interpreted the data	Analyzed the data	Formal analysis	YES
4908840	27301979	HBS	2	contributed to study concept and design|interpreted the data|participated in the drafting and critical revision of the manuscript	participated in the drafting and critical revision of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4908840	27301979	JH	2	participated in the sample and data collection	participated in the sample and data collection	Performed the experiments	Investigation	YES
4908840	27301979	JM	2	contributed to study concept and design|performed the statistical analysis|interpreted the data|participated in the drafting and critical revision of the manuscript	contributed to study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4908840	27301979	JM	2	contributed to study concept and design|performed the statistical analysis|interpreted the data|participated in the drafting and critical revision of the manuscript	performed the statistical analysis	Analyzed the data	Formal analysis	YES
4908840	27301979	JM	2	contributed to study concept and design|performed the statistical analysis|interpreted the data|participated in the drafting and critical revision of the manuscript	interpreted the data	Analyzed the data	Formal analysis	YES
4908840	27301979	JM	2	contributed to study concept and design|performed the statistical analysis|interpreted the data|participated in the drafting and critical revision of the manuscript	participated in the drafting and critical revision of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4908840	27301979	SKM	2	participated in the sample and data collection	participated in the sample and data collection	Performed the experiments	Investigation	YES
4908840	27301979	WE	2	participated in the sample and data collection	participated in the sample and data collection	Performed the experiments	Investigation	YES
4912719	27317430	DPW	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4912719	27317430	DPW	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4912719	27317430	FL	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4912719	27317430	FL	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4912719	27317430	HLZ	PLoS5	Provided the materials	Provided the materials	Contributed reagents/materials/analysis tools	Resources	YES
4912719	27317430	JK	PLoS5	Performed the experiments and identified the plant materials	Performed the experiments and identified the plant materials	Performed the experiments	Investigation	YES
4912719	27317430	KZ	PLoS5	Performed the experiments and identified the plant materials	Performed the experiments and identified the plant materials	Performed the experiments	Investigation	YES
4912719	27317430	WDK	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4912719	27317430	YPL	PLoS5	Provided the materials	Provided the materials	Contributed reagents/materials/analysis tools	Resources	YES
4912719	27317430	ZHL	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4912719	27317430	ZWL	PLoS5	Conceived and designed the experiments|Performed the experiments and identified the plant materials|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4912719	27317430	ZWL	PLoS5	Conceived and designed the experiments|Performed the experiments and identified the plant materials|Wrote the paper	Performed the experiments and identified the plant materials	Performed the experiments	Investigation	YES
4912719	27317430	ZWL	PLoS5	Conceived and designed the experiments|Performed the experiments and identified the plant materials|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4363613	25821832	Zhe Li	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
4363613	25821832	Zhongqi Fan	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
4912780	27315794	AA	CRediT	Development of methodology|Development of software|Writing, review, and/or revision of the manuscript	Development of methodology	Performed the experiments	Methodology	YES
4912780	27315794	AA	CRediT	Development of methodology|Development of software|Writing, review, and/or revision of the manuscript	Development of software	Contributed reagents/materials/analysis tools	Software	YES
4912780	27315794	AA	CRediT	Development of methodology|Development of software|Writing, review, and/or revision of the manuscript	Writing, review, and/or revision of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4912780	27315794	AM	CRediT	Conception and design|Development of software|Writing, review, and/or revision of the manuscript	Conception and design	Conceived and designed the experiments	Conceptualization	YES
4912780	27315794	AM	CRediT	Conception and design|Development of software|Writing, review, and/or revision of the manuscript	Development of software	Contributed reagents/materials/analysis tools	Software	YES
4912780	27315794	AM	CRediT	Conception and design|Development of software|Writing, review, and/or revision of the manuscript	Writing, review, and/or revision of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4912780	27315794	AR	CRediT	Conception and design|Development of methodology|Development of software|Writing, review, and/or revision of the manuscript|supervision	Conception and design	Conceived and designed the experiments	Conceptualization	YES
4912780	27315794	AR	CRediT	Conception and design|Development of methodology|Development of software|Writing, review, and/or revision of the manuscript|supervision	Development of methodology	Performed the experiments	Methodology	YES
4912780	27315794	AR	CRediT	Conception and design|Development of methodology|Development of software|Writing, review, and/or revision of the manuscript|supervision	Development of software	Contributed reagents/materials/analysis tools	Software	YES
4912780	27315794	AR	CRediT	Conception and design|Development of methodology|Development of software|Writing, review, and/or revision of the manuscript|supervision	Writing, review, and/or revision of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4912780	27315794	AR	CRediT	Conception and design|Development of methodology|Development of software|Writing, review, and/or revision of the manuscript|supervision	supervision	-	Supervision	YES
4912780	27315794	FM	CRediT	Writing, review, and/or revision of the manuscript	Writing, review, and/or revision of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4912780	27315794	JPR	CRediT	Development of methodology|Development of software|Writing, review, and/or revision of the manuscript	Development of methodology	Performed the experiments	Methodology	YES
4912780	27315794	JPR	CRediT	Development of methodology|Development of software|Writing, review, and/or revision of the manuscript	Development of software	Contributed reagents/materials/analysis tools	Software	YES
4912780	27315794	JPR	CRediT	Development of methodology|Development of software|Writing, review, and/or revision of the manuscript	Writing, review, and/or revision of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4912780	27315794	LMM	CRediT	Conception and design|Development of methodology|Writing, review, and/or revision of the manuscript|supervision	Conception and design	Conceived and designed the experiments	Conceptualization	YES
4912780	27315794	LMM	CRediT	Conception and design|Development of methodology|Writing, review, and/or revision of the manuscript|supervision	Development of methodology	Performed the experiments	Methodology	YES
4912780	27315794	LMM	CRediT	Conception and design|Development of methodology|Writing, review, and/or revision of the manuscript|supervision	Writing, review, and/or revision of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4912780	27315794	LMM	CRediT	Conception and design|Development of methodology|Writing, review, and/or revision of the manuscript|supervision	supervision	-	Supervision	YES
4912780	27315794	RP	CRediT	Conception and design|Development of methodology|Writing, review, and/or revision of the manuscript|supervision	Conception and design	Conceived and designed the experiments	Conceptualization	YES
4912780	27315794	RP	CRediT	Conception and design|Development of methodology|Writing, review, and/or revision of the manuscript|supervision	Development of methodology	Performed the experiments	Methodology	YES
4912780	27315794	RP	CRediT	Conception and design|Development of methodology|Writing, review, and/or revision of the manuscript|supervision	Writing, review, and/or revision of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4912780	27315794	RP	CRediT	Conception and design|Development of methodology|Writing, review, and/or revision of the manuscript|supervision	supervision	-	Supervision	YES
4363668	25821824	Jiayu Zhong	2	contributed equally to this work	contributed equally to this work	-	-	NO
4363668	25821824	Wei Zhao	2	contributed equally to this work	contributed equally to this work	-	-	NO
4363668	25821824	Wenying Luo	2	contributed equally to this work	contributed equally to this work	-	-	NO
4912826	27317562	GS	2	conceived the study and made substantial contribution for interpretation of the results and revised the manuscript	conceived the study and made substantial contribution for interpretation of the results and revised the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Review & Editing	YES
4912826	27317562	LJ	2	provided statistical analysis tools, made substantial contribution for interpretation of the results and revised the manuscript	provided statistical analysis tools, made substantial contribution for interpretation of the results and revised the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
4912826	27317562	MSL	2	conceived the study, made substantial contribution for interpretation of the results and revised the manuscript	conceived the study, made substantial contribution for interpretation of the results and revised the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Review & Editing	YES
4912826	27317562	OFC	2	conceived the study, provided statistical analysis tools, made substantial contribution for interpretation of the results and revised the manuscript	conceived the study, provided statistical analysis tools, made substantial contribution for interpretation of the results and revised the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Resources|Writing - Review & Editing	YES
4912826	27317562	XG	2	conceived the study, performed statistical analysis and wrote the manuscript	conceived the study, performed statistical analysis and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
4917956	27338614	A-MD	2	performed the single cell genomic workflow	performed the single cell genomic workflow	Performed the experiments	Investigation|Methodology	YES
4917956	27338614	All authors	2	have been participating in revising the manuscript and have approved it for publication	have been participating in revising the manuscript and have approved it for publication	Wrote the paper	Writing - Review & Editing	YES
4917956	27338614	BH	2	carried out all bioinformatic analysis	carried out all bioinformatic analysis	Performed the experiments	Formal analysis|Investigation	YES
4917956	27338614	CA	2	have isolated the parasite material and performed genome sequencing of the metagenome	have isolated the parasite material and performed genome sequencing of the metagenome	Performed the experiments	Investigation	YES
4917956	27338614	JB	2	participated in analysis	participated in analysis	-	-	NO
4917956	27338614	KT	2	designed the experiment, interpreted the data and wrote the manuscript	designed the experiment, interpreted the data and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4917956	27338614	MH	2	participated in bioinformatic analysis	participated in bioinformatic analysis	-	Formal analysis	YES
4917956	27338614	RA	2	participated in analysis and drafting of the manuscript	participated in analysis and drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
4917956	27338614	SB	2	designed the experiment, interpreted the data and wrote the manuscript	designed the experiment, interpreted the data and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4918139	27334613	KDS	2	conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4919871	27342569	AAA	2	participated in the design of the experiments and the analysis of the data	participated in the design of the experiments and the analysis of the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
4919871	27342569	DCT	2	performed the statistical analyses, plotted the data and helped to interpret the results in light of the literature	performed the statistical analyses, plotted the data and helped to interpret the results in light of the literature	Analyzed the data	Formal analysis|Visualization	YES
4919871	27342569	MJL	2	wrote the sql queries to map the motifs and their position in transcripts, quantified their inclusion by analyzing rna seq data|performed the statistical analyses, plotted the data and helped to interpret the results in light of the literature	wrote the sql queries to map the motifs and their position in transcripts, quantified their inclusion by analyzing rna seq data	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Software|Writing - Original Draft	YES
4919871	27342569	MJL	2	wrote the sql queries to map the motifs and their position in transcripts, quantified their inclusion by analyzing rna seq data|performed the statistical analyses, plotted the data and helped to interpret the results in light of the literature	performed the statistical analyses, plotted the data and helped to interpret the results in light of the literature	Analyzed the data	Formal analysis|Visualization	YES
4919871	27342569	MSS	2	performed the statistical analyses, plotted the data and helped to interpret the results in light of the literature|conceived and designed the study, participated in the analysis and interpretation of the results and wrote the manuscript	performed the statistical analyses, plotted the data and helped to interpret the results in light of the literature	Analyzed the data	Formal analysis|Visualization	YES
4919871	27342569	MSS	2	performed the statistical analyses, plotted the data and helped to interpret the results in light of the literature|conceived and designed the study, participated in the analysis and interpretation of the results and wrote the manuscript	conceived and designed the study, participated in the analysis and interpretation of the results and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
4920993	27342315	DS	2	analyzed de novo assembly and differentially expressed genes using bioinformatics tools	analyzed de novo assembly and differentially expressed genes using bioinformatics tools	Analyzed the data	Formal analysis	YES
4920993	27342315	GQC	2	wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
4920993	27342315	HUK	2	conceived and designed research|wrote the article|conducted the experiments and contributed to the study design	conceived and designed research	Conceived and designed the experiments	Conceptualization|Methodology	YES
4920993	27342315	HUK	2	conceived and designed research|wrote the article|conducted the experiments and contributed to the study design	wrote the article	Wrote the paper	Writing - Original Draft	YES
4920993	27342315	HUK	2	conceived and designed research|wrote the article|conducted the experiments and contributed to the study design	conducted the experiments and contributed to the study design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4920993	27342315	JHL	2	analyzed de novo assembly and differentially expressed genes using bioinformatics tools	analyzed de novo assembly and differentially expressed genes using bioinformatics tools	Analyzed the data	Formal analysis	YES
4920993	27342315	KYL	2	conducted the experiments and contributed to the study design	conducted the experiments and contributed to the study design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4920993	27342315	SH	2	conducted the experiments and contributed to the study design	conducted the experiments and contributed to the study design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4921024	27342196	ADH	2	together wrote the manuscript|gathered and refined the curated set of 131 known fusions in the b vitamin pathways|conceived of and oversaw the project	together wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4921024	27342196	ADH	2	together wrote the manuscript|gathered and refined the curated set of 131 known fusions in the b vitamin pathways|conceived of and oversaw the project	gathered and refined the curated set of 131 known fusions in the b vitamin pathways	Analyzed the data	Data curation	YES
4921024	27342196	ADH	2	together wrote the manuscript|gathered and refined the curated set of 131 known fusions in the b vitamin pathways|conceived of and oversaw the project	conceived of and oversaw the project	Conceived and designed the experiments	Conceptualization|Supervision	YES
4921024	27342196	CLO	2	together wrote the manuscript|gathered and refined the curated set of 131 known fusions in the b vitamin pathways	together wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4921024	27342196	CLO	2	together wrote the manuscript|gathered and refined the curated set of 131 known fusions in the b vitamin pathways	gathered and refined the curated set of 131 known fusions in the b vitamin pathways	Analyzed the data	Data curation	YES
4921024	27342196	CSH	2	together wrote the manuscript|developed the new fusion prediction algorithm|applied the algorithm to the pubseed genome database|analyzed the results of the fusion prediction, including performing all metabolic modeling used in the fusion analysis|conceived of and oversaw the project	together wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4921024	27342196	CSH	2	together wrote the manuscript|developed the new fusion prediction algorithm|applied the algorithm to the pubseed genome database|analyzed the results of the fusion prediction, including performing all metabolic modeling used in the fusion analysis|conceived of and oversaw the project	developed the new fusion prediction algorithm	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Software	YES
4921024	27342196	CSH	2	together wrote the manuscript|developed the new fusion prediction algorithm|applied the algorithm to the pubseed genome database|analyzed the results of the fusion prediction, including performing all metabolic modeling used in the fusion analysis|conceived of and oversaw the project	applied the algorithm to the pubseed genome database	Contributed reagents/materials/analysis tools	Software	YES
4921024	27342196	CSH	2	together wrote the manuscript|developed the new fusion prediction algorithm|applied the algorithm to the pubseed genome database|analyzed the results of the fusion prediction, including performing all metabolic modeling used in the fusion analysis|conceived of and oversaw the project	analyzed the results of the fusion prediction, including performing all metabolic modeling used in the fusion analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
4921024	27342196	CSH	2	together wrote the manuscript|developed the new fusion prediction algorithm|applied the algorithm to the pubseed genome database|analyzed the results of the fusion prediction, including performing all metabolic modeling used in the fusion analysis|conceived of and oversaw the project	conceived of and oversaw the project	Conceived and designed the experiments	Conceptualization|Supervision	YES
4921024	27342196	GH	2	gathered and refined the curated set of 131 known fusions in the b vitamin pathways	gathered and refined the curated set of 131 known fusions in the b vitamin pathways	Analyzed the data	Data curation	YES
4921024	27342196	JM	2	developed the new fusion prediction algorithm|applied the algorithm to the pubseed genome database	developed the new fusion prediction algorithm	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Software	YES
4921024	27342196	JM	2	developed the new fusion prediction algorithm|applied the algorithm to the pubseed genome database	applied the algorithm to the pubseed genome database	Contributed reagents/materials/analysis tools	Software	YES
4921024	27342196	JT	2	developed the new fusion prediction algorithm	developed the new fusion prediction algorithm	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Software	YES
4921024	27342196	NC	2	built the online web resource	built the online web resource	Contributed reagents/materials/analysis tools	-	YES
4921024	27342196	OF	2	gathered and refined the curated set of 131 known fusions in the b vitamin pathways	gathered and refined the curated set of 131 known fusions in the b vitamin pathways	Analyzed the data	Data curation	YES
4921024	27342196	RC	2	developed the new fusion prediction algorithm|applied the algorithm to the pubseed genome database	developed the new fusion prediction algorithm	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Software	YES
4921024	27342196	RC	2	developed the new fusion prediction algorithm|applied the algorithm to the pubseed genome database	applied the algorithm to the pubseed genome database	Contributed reagents/materials/analysis tools	Software	YES
4921024	27342196	RZ	2	gathered and refined the curated set of 131 known fusions in the b vitamin pathways	gathered and refined the curated set of 131 known fusions in the b vitamin pathways	Analyzed the data	Data curation	YES
4921024	27342196	SG	2	gathered and refined the curated set of 131 known fusions in the b vitamin pathways	gathered and refined the curated set of 131 known fusions in the b vitamin pathways	Analyzed the data	Data curation	YES
4921024	27342196	SYG	2	together wrote the manuscript	together wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4921024	27342196	TN	2	gathered and refined the curated set of 131 known fusions in the b vitamin pathways	gathered and refined the curated set of 131 known fusions in the b vitamin pathways	Analyzed the data	Data curation	YES
4921024	27342196	VdCL	2	together wrote the manuscript|gathered and refined the curated set of 131 known fusions in the b vitamin pathways|conceived of and oversaw the project	together wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4921024	27342196	VdCL	2	together wrote the manuscript|gathered and refined the curated set of 131 known fusions in the b vitamin pathways|conceived of and oversaw the project	gathered and refined the curated set of 131 known fusions in the b vitamin pathways	Analyzed the data	Data curation	YES
4921024	27342196	VdCL	2	together wrote the manuscript|gathered and refined the curated set of 131 known fusions in the b vitamin pathways|conceived of and oversaw the project	conceived of and oversaw the project	Conceived and designed the experiments	Conceptualization|Supervision	YES
4924250	27352627	CM	2	conducted the experiments	conducted the experiments	Performed the experiments	Investigation	YES
4924250	27352627	CW	2	contributed the plant materials	contributed the plant materials	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4924250	27352627	DZ	2	contributed the plant materials	contributed the plant materials	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4924250	27352627	MX	2	participated in the design of the work and contributed to the writing of the manuscript	participated in the design of the work and contributed to the writing of the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
4924250	27352627	QY	2	contributed the plant materials	contributed the plant materials	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4924250	27352627	YG	2	contributed equally to this research|participated in the design of the work and contributed to the writing of the manuscript|contributed the plant materials	contributed equally to this research	-	-	NO
4924250	27352627	YG	2	contributed equally to this research|participated in the design of the work and contributed to the writing of the manuscript|contributed the plant materials	participated in the design of the work and contributed to the writing of the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
4924250	27352627	YG	2	contributed equally to this research|participated in the design of the work and contributed to the writing of the manuscript|contributed the plant materials	contributed the plant materials	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4924250	27352627	YL	2	contributed equally to this research|wrote the manuscript and analyzed data|conducted the experiments	contributed equally to this research	-	-	NO
4924250	27352627	YL	2	contributed equally to this research|wrote the manuscript and analyzed data|conducted the experiments	wrote the manuscript and analyzed data	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4924250	27352627	YL	2	contributed equally to this research|wrote the manuscript and analyzed data|conducted the experiments	conducted the experiments	Performed the experiments	Investigation	YES
4924284	27350531	AG	2	performed sequencing|performed data analysis|drafted the manuscript|contributed to data interpretation and assisted in drafting of the manuscript	performed sequencing	Performed the experiments	Investigation	YES
4924284	27350531	AG	2	performed sequencing|performed data analysis|drafted the manuscript|contributed to data interpretation and assisted in drafting of the manuscript	performed data analysis	Analyzed the data	Formal analysis	YES
4924284	27350531	AG	2	performed sequencing|performed data analysis|drafted the manuscript|contributed to data interpretation and assisted in drafting of the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4924284	27350531	AG	2	performed sequencing|performed data analysis|drafted the manuscript|contributed to data interpretation and assisted in drafting of the manuscript	contributed to data interpretation and assisted in drafting of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4924284	27350531	DB	2	co-conceptualised the project, participated in experimental design, contributed to data interpretation and assisted in drafting of the manuscript	co-conceptualised the project, participated in experimental design, contributed to data interpretation and assisted in drafting of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4924284	27350531	GL	2	performed qpcr to quantify the bacterium|prepared plant materials, performed rna extraction, library preparation	performed qpcr to quantify the bacterium	Performed the experiments	Investigation	YES
4924284	27350531	GL	2	performed qpcr to quantify the bacterium|prepared plant materials, performed rna extraction, library preparation	prepared plant materials, performed rna extraction, library preparation	Performed the experiments	Investigation	YES
4924284	27350531	GPM	2	co-conceptualised the project, participated in experimental design, contributed to data interpretation and assisted in drafting of the manuscript	co-conceptualised the project, participated in experimental design, contributed to data interpretation and assisted in drafting of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4924284	27350531	MC	2	performed sequencing	performed sequencing	Performed the experiments	Investigation	YES
4924284	27350531	MM	2	performed qpcr to quantify the bacterium|drafted the manuscript|performed qpcr gene expression assays|contributed to data interpretation and assisted in drafting of the manuscript	performed qpcr to quantify the bacterium	Performed the experiments	Investigation	YES
4924284	27350531	MM	2	performed qpcr to quantify the bacterium|drafted the manuscript|performed qpcr gene expression assays|contributed to data interpretation and assisted in drafting of the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4924284	27350531	MM	2	performed qpcr to quantify the bacterium|drafted the manuscript|performed qpcr gene expression assays|contributed to data interpretation and assisted in drafting of the manuscript	performed qpcr gene expression assays	Performed the experiments	Investigation	YES
4924284	27350531	MM	2	performed qpcr to quantify the bacterium|drafted the manuscript|performed qpcr gene expression assays|contributed to data interpretation and assisted in drafting of the manuscript	contributed to data interpretation and assisted in drafting of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4924284	27350531	MS	2	prepared plant materials, performed rna extraction, library preparation|co-conceptualised the project, participated in experimental design, contributed to data interpretation and assisted in drafting of the manuscript	prepared plant materials, performed rna extraction, library preparation	Performed the experiments	Investigation	YES
4924284	27350531	MS	2	prepared plant materials, performed rna extraction, library preparation|co-conceptualised the project, participated in experimental design, contributed to data interpretation and assisted in drafting of the manuscript	co-conceptualised the project, participated in experimental design, contributed to data interpretation and assisted in drafting of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4924284	27350531	PS	2	drafted the manuscript|contributed to data interpretation and assisted in drafting of the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4924284	27350531	PS	2	drafted the manuscript|contributed to data interpretation and assisted in drafting of the manuscript	contributed to data interpretation and assisted in drafting of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4924284	27350531	VS	2	co-conceptualised the project, participated in experimental design, contributed to data interpretation and assisted in drafting of the manuscript	co-conceptualised the project, participated in experimental design, contributed to data interpretation and assisted in drafting of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4924289	27350342	AG	7	Study design, data collection, data analysis, writing of the manuscript	Study design, data collection, data analysis, writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4924289	27350342	DMC	7	Data analysis	Data analysis	Analyzed the data	Formal analysis	YES
4924289	27350342	SCH	7	Study design, writing of the manuscript. JDW -Study design, data collection, data analysis, writing of the manuscript	Study design, writing of the manuscript. JDW -Study design, data collection, data analysis, writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4363986	25821786	Lu Qian	2	contributed equally to this work	contributed equally to this work	-	-	NO
4364024	25821795	Guoqiang Wang	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
4364024	25821795	Guoqiang Wang	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
4364024	25821795	Jifei Tang	PLoS52	conceived and designed the experiments|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4364024	25821795	Jifei Tang	PLoS52	conceived and designed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4364024	25821795	Kangting Ji	PLoS52	conceived and designed the experiments|wrote the paper|both contributed to this paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4364024	25821795	Kangting Ji	PLoS52	conceived and designed the experiments|wrote the paper|both contributed to this paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4364024	25821795	Kangting Ji	PLoS52	conceived and designed the experiments|wrote the paper|both contributed to this paper	both contributed to this paper	-	-	NO
4364024	25821795	Lianming Liao	PLoS52	conceived and designed the experiments|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4364024	25821795	Lianming Liao	PLoS52	conceived and designed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4364024	25821795	Lu Qian	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
4364024	25821795	Lu Qian	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
4364024	25821795	Luping Wang	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
4364024	25821795	Luping Wang	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
4364024	25821795	Qin Lu	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
4364024	25821795	Qin Lu	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
4364024	25821795	Suqin Zhang	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
4364024	25821795	Suqin Zhang	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
4364024	25821795	Wenwu Wu	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
4364024	25821795	Wenwu Wu	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
4364024	25821795	Xiaoyan Wang	PLoS52	performed the experiments|analyzed the data|wrote the paper|both contributed to this paper	performed the experiments	Performed the experiments	Investigation	YES
4364024	25821795	Xiaoyan Wang	PLoS52	performed the experiments|analyzed the data|wrote the paper|both contributed to this paper	analyzed the data	Analyzed the data	Formal analysis	YES
4364024	25821795	Xiaoyan Wang	PLoS52	performed the experiments|analyzed the data|wrote the paper|both contributed to this paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4364024	25821795	Xiaoyan Wang	PLoS52	performed the experiments|analyzed the data|wrote the paper|both contributed to this paper	both contributed to this paper	-	-	NO
4364024	25821795	Yangjing Xue	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
4364024	25821795	Yangjing Xue	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
4364024	25821795	Yongjin Zhu	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
4364024	25821795	Yongjin Zhu	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
4928156	27356511	All authors	2	critically revised and approved the manuscript	critically revised and approved the manuscript	Wrote the paper	Writing - Review & Editing	YES
4928156	27356511	CS	2	conceived and designed the work and wrote the paper|implemented and tested inps3d	conceived and designed the work and wrote the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4928156	27356511	CS	2	conceived and designed the work and wrote the paper|implemented and tested inps3d	implemented and tested inps3d	Performed the experiments	Investigation	YES
4928156	27356511	FA	2	curated the datasets and collaborated in data analysis	curated the datasets and collaborated in data analysis	Analyzed the data	Data curation|Formal analysis	YES
4928156	27356511	GB	2	curated the datasets and collaborated in data analysis	curated the datasets and collaborated in data analysis	Analyzed the data	Data curation|Formal analysis	YES
4928156	27356511	PF	2	conceived and designed the work and wrote the paper|implemented and tested inps3d	conceived and designed the work and wrote the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4928156	27356511	PF	2	conceived and designed the work and wrote the paper|implemented and tested inps3d	implemented and tested inps3d	Performed the experiments	Investigation	YES
4928156	27356511	PLM	2	conceived and designed the work and wrote the paper|analysed and interpreted data on disease related variations	conceived and designed the work and wrote the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4928156	27356511	PLM	2	conceived and designed the work and wrote the paper|analysed and interpreted data on disease related variations	analysed and interpreted data on disease related variations	Analyzed the data	Formal analysis	YES
4928156	27356511	RC	2	conceived and designed the work and wrote the paper|analysed and interpreted data on disease related variations	conceived and designed the work and wrote the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4928156	27356511	RC	2	conceived and designed the work and wrote the paper|analysed and interpreted data on disease related variations	analysed and interpreted data on disease related variations	Analyzed the data	Formal analysis	YES
4928159	27357578	EC	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4928159	27357578	HC	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4928159	27357578	YB	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4928267	27357509	AJM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4928267	27357509	ARJ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4928267	27357509	DM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4928267	27357509	DV	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4928267	27357509	JLJ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4928267	27357509	JS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4928267	27357509	JS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4928267	27357509	JW	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4928267	27357509	PJB	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4928267	27357509	RE	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4928267	27357509	SM	PLoS5	Conceived and designed the experiments|Performed the experiment|Analyzed the data|Wrote the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4928267	27357509	SM	PLoS5	Conceived and designed the experiments|Performed the experiment|Analyzed the data|Wrote the manuscript	Performed the experiment	Performed the experiments	Investigation	YES
4928267	27357509	SM	PLoS5	Conceived and designed the experiments|Performed the experiment|Analyzed the data|Wrote the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4928267	27357509	SM	PLoS5	Conceived and designed the experiments|Performed the experiment|Analyzed the data|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4928267	27357509	SVK	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4928267	27357509	WW	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4928267	27357509	ZM	PLoS5	Conceived and designed the experiments|Performed the experiment|Analyzed the data|Wrote the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4928267	27357509	ZM	PLoS5	Conceived and designed the experiments|Performed the experiment|Analyzed the data|Wrote the manuscript	Performed the experiment	Performed the experiments	Investigation	YES
4928267	27357509	ZM	PLoS5	Conceived and designed the experiments|Performed the experiment|Analyzed the data|Wrote the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4928267	27357509	ZM	PLoS5	Conceived and designed the experiments|Performed the experiment|Analyzed the data|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4928513	27334470	PCG	2	performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
5329924	28265433	AD	2	was responsible for the clinical tests, drafted the manuscript and assisted with data analysis and interpretation	was responsible for the clinical tests, drafted the manuscript and assisted with data analysis and interpretation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5329924	28265433	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5329924	28265433	IK	2	conceived the idea for the case study, drafted the manuscript, and was responsible for data acquisition and analysis	conceived the idea for the case study, drafted the manuscript, and was responsible for data acquisition and analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
5329924	28265433	RY	2	helped to draft the manuscript and with data analysis	helped to draft the manuscript and with data analysis	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5329924	28265433	YE	2	helped with the interpretation of data and was involved in drafting the manuscript	helped with the interpretation of data and was involved in drafting the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5329924	28265433	YH	2	conceived the idea for the case study, was responsible for the manuscript design, the interpretation of the data and the writing process and approval	conceived the idea for the case study, was responsible for the manuscript design, the interpretation of the data and the writing process and approval	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Data curation|Formal analysis|Methodology|Writing - Original Draft	YES
4929742	27364156	All authors	2	participated in writing the manuscript and have read and approved the final version	participated in writing the manuscript and have read and approved the final version	Wrote the paper	Writing - Original Draft	YES
4929742	27364156	CD	2	designed the genetic experiments and drafted the paper	designed the genetic experiments and drafted the paper	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
4929742	27364156	FJM	2	did the ct scanning	did the ct scanning	-	-	NO
4929742	27364156	FM	2	performed linkage mapping and genotyping	performed linkage mapping and genotyping	Performed the experiments	Investigation	YES
4929742	27364156	JSA	2	was study leader and examined the defective calves	was study leader and examined the defective calves	-	Supervision	YES
4929742	27364156	VJ	2	performed bioinformatics	performed bioinformatics	Performed the experiments	Formal analysis|Investigation	YES
5329930	28265447	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5329930	28265447	CG	2	contributed equally to all sections of the article	contributed equally to all sections of the article	-	-	NO
5329930	28265447	LM	2	contributed equally to all sections of the article	contributed equally to all sections of the article	-	-	NO
5329930	28265447	PE	2	contributed equally to all sections of the article	contributed equally to all sections of the article	-	-	NO
4929757	27363999	BEL	2	provided critical inputs to the study and were involved in the finalization of the manuscript	provided critical inputs to the study and were involved in the finalization of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4929757	27363999	BH	2	directed the bioinformatics analysis and data interpretation and participated in writing the manuscript	directed the bioinformatics analysis and data interpretation and participated in writing the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Supervision|Writing - Original Draft	YES
4929757	27363999	JKP	2	provided critical inputs to the study and were involved in the finalization of the manuscript	provided critical inputs to the study and were involved in the finalization of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4929757	27363999	MEH	2	participated in the study design, carried out laboratory work, performed the bioinformatic analysis and drafted the manuscript	participated in the study design, carried out laboratory work, performed the bioinformatic analysis and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4929757	27363999	XLP	2	conceived and supervised the study and revised the manuscript	conceived and supervised the study and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Supervision|Writing - Review & Editing	YES
4365313	25834816	Lifang Ding	2	contributed equally to this paper and should be considered co-first authors	contributed equally to this paper and should be considered co-first authors	-	-	NO
4365313	25834816	Zao Jiang	2	contributed equally to this paper and should be considered co-first authors	contributed equally to this paper and should be considered co-first authors	-	-	NO
5329941	28265451	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5329941	28265451	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5329941	28265451	YZ	2	analyzed the data, interpreted the data and wrote the paper	analyzed the data, interpreted the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4930560	27368698	KAB	2	conceived and designed the experiment|drafted the manuscript|supervised the project	conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
4930560	27368698	KAB	2	conceived and designed the experiment|drafted the manuscript|supervised the project	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4930560	27368698	KAB	2	conceived and designed the experiment|drafted the manuscript|supervised the project	supervised the project	-	Supervision	YES
4930560	27368698	SL	2	conceived and designed the experiment|conducted the experiments and analyzed the data|drafted the manuscript	conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
4930560	27368698	SL	2	conceived and designed the experiment|conducted the experiments and analyzed the data|drafted the manuscript	conducted the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4930560	27368698	SL	2	conceived and designed the experiment|conducted the experiments and analyzed the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4930560	27368698	SLB	2	conceived and designed the experiment|drafted the manuscript|supervised the project	conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
4930560	27368698	SLB	2	conceived and designed the experiment|drafted the manuscript|supervised the project	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4930560	27368698	SLB	2	conceived and designed the experiment|drafted the manuscript|supervised the project	supervised the project	-	Supervision	YES
5329943	28265445	AE	2	conceived the study|drafted the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5329943	28265445	AE	2	conceived the study|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5329943	28265445	AS	2	participated in the design of the study|performed the statistical analysis	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
5329943	28265445	AS	2	participated in the design of the study|performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
5329943	28265445	All authors	2	participated in the study and data collection|read and approved the final manuscript	participated in the study and data collection	Performed the experiments	Investigation	YES
5329943	28265445	All authors	2	participated in the study and data collection|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5329943	28265445	IN	2	conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5329943	28265445	SR	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5329943	28265445	SS	2	participated in the design of the study	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
5329943	28265445	YR	2	conceived the study|drafted the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5329943	28265445	YR	2	conceived the study|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
493266	15265237	AH	2	conceived the study, participated in its design and coordination	conceived the study, participated in its design and coordination	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
493266	15265237	AR	2	performed the molecular genetic studies, participated in the statistical analysis and drafted the manuscript	performed the molecular genetic studies, participated in the statistical analysis and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
493266	15265237	CH	2	were responsible for the data mining	were responsible for the data mining	Analyzed the data	Formal analysis	YES
493266	15265237	MOD	2	participated in the design of the study and the statistical analysis	participated in the design of the study and the statistical analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
493266	15265237	NG	2	were responsible for the data mining	were responsible for the data mining	Analyzed the data	Formal analysis	YES
493266	15265237	TC	2	were responsible for the data mining	were responsible for the data mining	Analyzed the data	Formal analysis	YES
5329946	28265438	DG	1	Conception and design, analysis and interpretation, writing the article, critical revision of the article, overall responsibility	Conception and design, analysis and interpretation, writing the article, critical revision of the article, overall responsibility	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5329946	28265438	EZ	1	Conception and design, analysis and interpretation, writing the article, critical revision of the article, overall responsibility	Conception and design, analysis and interpretation, writing the article, critical revision of the article, overall responsibility	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5329946	28265438	OH	1	Conception and design, analysis and interpretation, writing the article, critical revision of the article, overall responsibility	Conception and design, analysis and interpretation, writing the article, critical revision of the article, overall responsibility	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5329946	28265438	YK	1	Conception and design, analysis and interpretation, writing the article, critical revision of the article, overall responsibility	Conception and design, analysis and interpretation, writing the article, critical revision of the article, overall responsibility	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5329947	28265444	AI	2	participated in data collection and intervention	participated in data collection and intervention	Performed the experiments	Investigation	YES
5329947	28265444	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5329947	28265444	EF	2	helped in researching for the manuscript	helped in researching for the manuscript	-	-	NO
5329947	28265444	IDF	2	approved the study and waived the requirement for informed consent in order to protect participant anonymity	approved the study and waived the requirement for informed consent in order to protect participant anonymity	-	-	NO
5329947	28265444	IO	2	participated in data collection, intervention, analysis, and wrote the manuscript	participated in data collection, intervention, analysis, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5329947	28265444	LTL	2	participated in data collection, intervention, and helped write the manuscript	participated in data collection, intervention, and helped write the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5329947	28265444	Medical Corps	2	approved the study and waived the requirement for informed consent in order to protect participant anonymity	approved the study and waived the requirement for informed consent in order to protect participant anonymity	-	-	NO
5329947	28265444	OS	2	participated in analysis, provided theoretical aspects and helped write the manuscript	participated in analysis, provided theoretical aspects and helped write the manuscript	Wrote the paper	Formal analysis|Writing - Original Draft	YES
5329947	28265444	SMHT	2	helped draft the manuscript	helped draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5329947	28265444	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
4932673	27377915	All authors	2	contributed to this work and have read and approved the most recent version of the manuscript	contributed to this work and have read and approved the most recent version of the manuscript	-	-	NO
4754298	28330138	AM	PLoS52	developed the software	developed the software	Contributed reagents/materials/analysis tools	Software	YES
4754298	28330138	CGJ	PLoS52	conceived and designed the study|wrote the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4754298	28330138	CGJ	PLoS52	conceived and designed the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4754298	28330138	NVP	PLoS52	developed the software|analyzed the data	developed the software	Contributed reagents/materials/analysis tools	Software	YES
4754298	28330138	NVP	PLoS52	developed the software|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
4754298	28330138	RM	PLoS52	conceived and designed the study|developed the software|analyzed the data|supervised the study|wrote the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4754298	28330138	RM	PLoS52	conceived and designed the study|developed the software|analyzed the data|supervised the study|wrote the manuscript	developed the software	Contributed reagents/materials/analysis tools	Software	YES
4754298	28330138	RM	PLoS52	conceived and designed the study|developed the software|analyzed the data|supervised the study|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
4754298	28330138	RM	PLoS52	conceived and designed the study|developed the software|analyzed the data|supervised the study|wrote the manuscript	supervised the study	-	Supervision	YES
4754298	28330138	RM	PLoS52	conceived and designed the study|developed the software|analyzed the data|supervised the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5329956	28265443	AS	2	have participated in reviewing the literature, drafting or revising of the manuscript, and they have approved the manuscript as submitted	have participated in reviewing the literature, drafting or revising of the manuscript, and they have approved the manuscript as submitted	Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5329956	28265443	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5329956	28265443	BL	2	have participated in reviewing the literature, drafting or revising of the manuscript, and they have approved the manuscript as submitted	have participated in reviewing the literature, drafting or revising of the manuscript, and they have approved the manuscript as submitted	Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5329956	28265443	DN	2	have participated in reviewing the literature, drafting or revising of the manuscript, and they have approved the manuscript as submitted	have participated in reviewing the literature, drafting or revising of the manuscript, and they have approved the manuscript as submitted	Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5329956	28265443	EZ	2	have participated in reviewing the literature, drafting or revising of the manuscript, and they have approved the manuscript as submitted	have participated in reviewing the literature, drafting or revising of the manuscript, and they have approved the manuscript as submitted	Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5329956	28265443	IF	2	have participated in reviewing the literature, drafting or revising of the manuscript, and they have approved the manuscript as submitted	have participated in reviewing the literature, drafting or revising of the manuscript, and they have approved the manuscript as submitted	Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5329956	28265443	MS	2	have participated in reviewing the literature, drafting or revising of the manuscript, and they have approved the manuscript as submitted	have participated in reviewing the literature, drafting or revising of the manuscript, and they have approved the manuscript as submitted	Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5329958	28265455	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5329958	28265455	BG	2	conceived of the study, designed the questionnaire, preformed the statistical analysis, and drafted the manuscript	conceived of the study, designed the questionnaire, preformed the statistical analysis, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5329958	28265455	EC	2	helped in the coordination and supervision of the study, and critically reviewed the manuscript	helped in the coordination and supervision of the study, and critically reviewed the manuscript	Wrote the paper	Project administration|Supervision|Writing - Review & Editing	YES
5329958	28265455	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5329958	28265455	YE	2	helped in designing the study and critically reviewed the manuscript	helped in designing the study and critically reviewed the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
4938905	27391971	GB	2	performed the disease diagnostic analysis and collected the samples	performed the disease diagnostic analysis and collected the samples	Performed the experiments	Investigation	YES
4938905	27391971	JG	2	planned and supervised the study	planned and supervised the study	Conceived and designed the experiments	Conceptualization|Supervision	YES
4938905	27391971	NW	2	planned and supervised the study|drafted the manuscript|wrote the final version	planned and supervised the study	Conceived and designed the experiments	Conceptualization|Supervision	YES
4938905	27391971	NW	2	planned and supervised the study|drafted the manuscript|wrote the final version	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4938905	27391971	NW	2	planned and supervised the study|drafted the manuscript|wrote the final version	wrote the final version	Wrote the paper	Writing - Original Draft	YES
4938905	27391971	YZ	2	performed the disease diagnostic analysis and collected the samples|performed the genome assembly and rna seq analysis and rt qpcr validation|drafted the manuscript	performed the disease diagnostic analysis and collected the samples	Performed the experiments	Investigation	YES
4938905	27391971	YZ	2	performed the disease diagnostic analysis and collected the samples|performed the genome assembly and rna seq analysis and rt qpcr validation|drafted the manuscript	performed the genome assembly and rna seq analysis and rt qpcr validation	Performed the experiments	Investigation|Validation	YES
4938905	27391971	YZ	2	performed the disease diagnostic analysis and collected the samples|performed the genome assembly and rna seq analysis and rt qpcr validation|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4938946	27393338	AS	2	performed the computational analysis, data interpretation and prepared figures and text for the manuscript	performed the computational analysis, data interpretation and prepared figures and text for the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Visualization|Writing - Original Draft	YES
4938946	27393338	DF	2	carried out experimental work for the manuscript	carried out experimental work for the manuscript	Performed the experiments	Investigation	YES
4938946	27393338	DM	2	designed the study and drafted the manuscript	designed the study and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4938946	27393338	ER	2	performed the snp array experiments	performed the snp array experiments	Performed the experiments	Investigation	YES
4938946	27393338	JD	2	designed the study and drafted the manuscript|carried out experimental work for the manuscript	designed the study and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4938946	27393338	JD	2	designed the study and drafted the manuscript|carried out experimental work for the manuscript	carried out experimental work for the manuscript	Performed the experiments	Investigation	YES
4938946	27393338	JS	2	performed the sequencing experiments for the manuscript	performed the sequencing experiments for the manuscript	Performed the experiments	Investigation	YES
4938946	27393338	KK	2	performed the sequencing experiments for the manuscript	performed the sequencing experiments for the manuscript	Performed the experiments	Investigation	YES
4938946	27393338	KM	2	carried out experimental work for the manuscript	carried out experimental work for the manuscript	Performed the experiments	Investigation	YES
4938946	27393338	MD	2	performed the computational analysis, data interpretation and prepared figures and text for the manuscript	performed the computational analysis, data interpretation and prepared figures and text for the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Visualization|Writing - Original Draft	YES
4938946	27393338	PC	2	performed the computational analysis, data interpretation and prepared figures and text for the manuscript	performed the computational analysis, data interpretation and prepared figures and text for the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Visualization|Writing - Original Draft	YES
4938946	27393338	XG	2	performed the computational analysis, data interpretation and prepared figures and text for the manuscript	performed the computational analysis, data interpretation and prepared figures and text for the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Visualization|Writing - Original Draft	YES
5330008	28265441	AAA	2	also drafted the introduction and revised the manuscript	also drafted the introduction and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5330008	28265441	AE	2	drafted the section of the epsilon toxin and critically revised the manuscript	drafted the section of the epsilon toxin and critically revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5330008	28265441	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5330008	28265441	IF	2	drafted the sections of the seb and epsilon toxin and critically revised the manuscript	drafted the sections of the seb and epsilon toxin and critically revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5330008	28265441	MK	2	drafted the introduction section	drafted the introduction section	Wrote the paper	Writing - Original Draft	YES
4365336	25834818	Bulent Tunerir	2	designed the study and helped to draft the paper	designed the study and helped to draft the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4365336	25834818	Firat Altin	2	was responsible for animal selection, design, and coordination	was responsible for animal selection, design, and coordination	Conceived and designed the experiments	Project administration	YES
4365336	25834818	Kamuran Erkoc	2	designed the study and carried out animal selection and design and coordination	designed the study and carried out animal selection and design and coordination	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Project administration	YES
4365336	25834818	Onur Uysal	2	was responsible for design and coordination	was responsible for design and coordination	Conceived and designed the experiments	Project administration	YES
4365336	25834818	Osman Tiryakioglu	2	designed the study and performed the statistical analysis design and coordination	designed the study and performed the statistical analysis design and coordination	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology|Project administration	YES
4365336	25834818	Selim Aydin	2	helped to draft the paper	helped to draft the paper	Wrote the paper	Writing - Original Draft	YES
4365336	25834818	Tevfik Gunes	2	designed the study and performed the statistical analysis	designed the study and performed the statistical analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5330020	28265446	Both authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5330020	28265446	OB	2	conceived the study, participated in the design of the study and in the study and data collection|performed the statistical analysis and drafted the manuscript	conceived the study, participated in the design of the study and in the study and data collection	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
5330020	28265446	OB	2	conceived the study, participated in the design of the study and in the study and data collection|performed the statistical analysis and drafted the manuscript	performed the statistical analysis and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5330020	28265446	RB	2	performed the statistical analysis and drafted the manuscript	performed the statistical analysis and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4940881	27401861	ACC	2	designed and performed experiments, analysed data and wrote manuscript	designed and performed experiments, analysed data and wrote manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4940881	27401861	BK	2	designed experiments, analysed data and wrote manuscript	designed experiments, analysed data and wrote manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4940881	27401861	SE	2	performed experiments and analysed data	performed experiments and analysed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5330033	28265448	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5330034	28265435	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5330034	28265435	All the authors	2	read, revised and approved the final manuscript	read, revised and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5330034	28265435	RD	2	conceived of the study and all the authors participated in the design of the study and planning of the data analysis	conceived of the study and all the authors participated in the design of the study and planning of the data analysis	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
5330034	28265435	SV	2	retrieved the data from the hmo database	retrieved the data from the hmo database	Contributed reagents/materials/analysis tools	Software	YES
5330034	28265435	VS	2	conceived of the study and all the authors participated in the design of the study and planning of the data analysis|drafted the manuscript	conceived of the study and all the authors participated in the design of the study and planning of the data analysis	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
5330034	28265435	VS	2	conceived of the study and all the authors participated in the design of the study and planning of the data analysis|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4940957	27401977	MHRV	2	collaborated on research design, suggested and validated the protocol for male meiocyte isolation, provided plant materials, and contributed to experimental design, as well as to the interpretation of the results, making important intellectual contributions and critically reviewing the manuscript	collaborated on research design, suggested and validated the protocol for male meiocyte isolation, provided plant materials, and contributed to experimental design, as well as to the interpretation of the results, making important intellectual contributions and critically reviewing the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Validation|Writing - Review & Editing	YES
4940957	27401977	NMVFZ	2	made substantial contributions to the research design, performed the bioinformatics analyses, interpreted the results, and wrote the first draft of the manuscript	made substantial contributions to the research design, performed the bioinformatics analyses, interpreted the results, and wrote the first draft of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4940957	27401977	OM	2	conceived and designed the research, directed the bioinformatics and statistical analyses, contributed to the interpretation of the results and wrote the final version of the manuscript	conceived and designed the research, directed the bioinformatics and statistical analyses, contributed to the interpretation of the results and wrote the final version of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Supervision|Writing - Original Draft	YES
5330089	28265432	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5330089	28265432	FY	2	supervised the study process	supervised the study process	-	Supervision	YES
5330089	28265432	JS	2	performed the manual searches for the additional articles|reviewed the potential study papers and made decisions on papers to be included|drafted the manuscript	performed the manual searches for the additional articles	Performed the experiments	Investigation	YES
5330089	28265432	JS	2	performed the manual searches for the additional articles|reviewed the potential study papers and made decisions on papers to be included|drafted the manuscript	reviewed the potential study papers and made decisions on papers to be included	Wrote the paper	Writing - Review & Editing	YES
5330089	28265432	JS	2	performed the manual searches for the additional articles|reviewed the potential study papers and made decisions on papers to be included|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5330089	28265432	KK	2	performed the manual searches for the additional articles|drafted the manuscript	performed the manual searches for the additional articles	Performed the experiments	Investigation	YES
5330089	28265432	KK	2	performed the manual searches for the additional articles|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5330089	28265432	MT	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5330089	28265432	NH	2	carried out the initial literature search|performed the manual searches for the additional articles|reviewed the potential study papers and made decisions on papers to be included|drafted the manuscript	carried out the initial literature search	Performed the experiments	Formal analysis|Investigation	YES
5330089	28265432	NH	2	carried out the initial literature search|performed the manual searches for the additional articles|reviewed the potential study papers and made decisions on papers to be included|drafted the manuscript	performed the manual searches for the additional articles	Performed the experiments	Investigation	YES
5330089	28265432	NH	2	carried out the initial literature search|performed the manual searches for the additional articles|reviewed the potential study papers and made decisions on papers to be included|drafted the manuscript	reviewed the potential study papers and made decisions on papers to be included	Wrote the paper	Writing - Review & Editing	YES
5330089	28265432	NH	2	carried out the initial literature search|performed the manual searches for the additional articles|reviewed the potential study papers and made decisions on papers to be included|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5330089	28265432	ST	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4942892	27411304	CC	2	designed the project|wrote the manuscript	designed the project	Conceived and designed the experiments	Methodology	YES
4942892	27411304	CC	2	designed the project|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4942892	27411304	FB	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4942892	27411304	GG	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4942892	27411304	GH	2	performed the strain isolation and molecular typing	performed the strain isolation and molecular typing	Performed the experiments	Investigation	YES
4942892	27411304	HJ	2	designed the project|wrote the manuscript|performed the strain isolation and molecular typing	designed the project	Conceived and designed the experiments	Methodology	YES
4942892	27411304	HJ	2	designed the project|wrote the manuscript|performed the strain isolation and molecular typing	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4942892	27411304	HJ	2	designed the project|wrote the manuscript|performed the strain isolation and molecular typing	performed the strain isolation and molecular typing	Performed the experiments	Investigation	YES
4942892	27411304	HW	2	performed the bioinformatics analysis	performed the bioinformatics analysis	Performed the experiments	Formal analysis|Investigation	YES
4942892	27411304	HY	2	wrote the manuscript|performed the strain isolation and molecular typing	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4942892	27411304	HY	2	wrote the manuscript|performed the strain isolation and molecular typing	performed the strain isolation and molecular typing	Performed the experiments	Investigation	YES
4942892	27411304	JW	2	performed the strain isolation and molecular typing	performed the strain isolation and molecular typing	Performed the experiments	Investigation	YES
4942892	27411304	JZ	2	performed the epidemiological study	performed the epidemiological study	Performed the experiments	Investigation	YES
4942892	27411304	NH	2	performed the bioinformatics analysis	performed the bioinformatics analysis	Performed the experiments	Formal analysis|Investigation	YES
4942892	27411304	PD	2	wrote the manuscript|performed the bioinformatics analysis	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4942892	27411304	PD	2	wrote the manuscript|performed the bioinformatics analysis	performed the bioinformatics analysis	Performed the experiments	Formal analysis|Investigation	YES
4942892	27411304	QD	2	performed the epidemiological study	performed the epidemiological study	Performed the experiments	Investigation	YES
4942892	27411304	WZ	2	performed the bioinformatics analysis	performed the bioinformatics analysis	Performed the experiments	Formal analysis|Investigation	YES
4942892	27411304	YC	2	designed the project|designed the project|wrote the manuscript|performed the epidemiological study	designed the project	Conceived and designed the experiments	Methodology	YES
4942892	27411304	YC	2	designed the project|designed the project|wrote the manuscript|performed the epidemiological study	designed the project	Conceived and designed the experiments	Methodology	YES
4942892	27411304	YC	2	designed the project|designed the project|wrote the manuscript|performed the epidemiological study	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4942892	27411304	YC	2	designed the project|designed the project|wrote the manuscript|performed the epidemiological study	performed the epidemiological study	Performed the experiments	Investigation	YES
4942892	27411304	YQ	2	performed the whole genome sequencing	performed the whole genome sequencing	Performed the experiments	Investigation	YES
4942892	27411304	YZ	2	wrote the manuscript|performed the whole genome sequencing	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4942892	27411304	YZ	2	wrote the manuscript|performed the whole genome sequencing	performed the whole genome sequencing	Performed the experiments	Investigation	YES
4942892	27411304	ZW	2	performed the bioinformatics analysis	performed the bioinformatics analysis	Performed the experiments	Formal analysis|Investigation	YES
4942892	27411304	ZY	2	performed the epidemiological study	performed the epidemiological study	Performed the experiments	Investigation	YES
5330112	28265434	Both authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5330112	28265434	ST	2	participated in the article design and coordination and helped to draft the manuscript	participated in the article design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Project administration|Writing - Original Draft	YES
5330112	28265434	TO	2	engaged in the whole scheme and application of disaster specific medical transportation, and described the design and implementation	engaged in the whole scheme and application of disaster specific medical transportation, and described the design and implementation	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5330114	28265437	AE	2	participated in the design of the study|drafted the manuscript|declare no funding source for this research	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
5330114	28265437	AE	2	participated in the design of the study|drafted the manuscript|declare no funding source for this research	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5330114	28265437	AE	2	participated in the design of the study|drafted the manuscript|declare no funding source for this research	declare no funding source for this research	-	Funding acquisition	YES
5330114	28265437	All authors	2	participated in the study and data collection|read and approved the final manuscript	participated in the study and data collection	Performed the experiments	Investigation	YES
5330114	28265437	All authors	2	participated in the study and data collection|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5330114	28265437	EB	2	conceived the study|participated in the design of the study|performed the statistical analysis|drafted the manuscript|declare no funding source for this research	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5330114	28265437	EB	2	conceived the study|participated in the design of the study|performed the statistical analysis|drafted the manuscript|declare no funding source for this research	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
5330114	28265437	EB	2	conceived the study|participated in the design of the study|performed the statistical analysis|drafted the manuscript|declare no funding source for this research	performed the statistical analysis	Analyzed the data	Formal analysis	YES
5330114	28265437	EB	2	conceived the study|participated in the design of the study|performed the statistical analysis|drafted the manuscript|declare no funding source for this research	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5330114	28265437	EB	2	conceived the study|participated in the design of the study|performed the statistical analysis|drafted the manuscript|declare no funding source for this research	declare no funding source for this research	-	Funding acquisition	YES
5330114	28265437	MS	2	participated in the design of the study	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
5330114	28265437	SO	2	performed the statistical analysis|declare no funding source for this research	performed the statistical analysis	Analyzed the data	Formal analysis	YES
5330114	28265437	SO	2	performed the statistical analysis|declare no funding source for this research	declare no funding source for this research	-	Funding acquisition	YES
5330114	28265437	YB	2	participated in the design of the study|declare no funding source for this research	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
5330114	28265437	YB	2	participated in the design of the study|declare no funding source for this research	declare no funding source for this research	-	Funding acquisition	YES
4365379	25834823	Eun-Jung Lee	PLoS52	designed research|conducted research|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
4365379	25834823	Eun-Jung Lee	PLoS52	designed research|conducted research|wrote the paper	conducted research	Performed the experiments	Investigation	YES
4365379	25834823	Eun-Jung Lee	PLoS52	designed research|conducted research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4365379	25834823	Ju-Hyun Gong	PLoS52	conducted research	conducted research	Performed the experiments	Investigation	YES
4365379	25834823	Jung-Lye Kim	PLoS52	designed research|conducted research	designed research	Conceived and designed the experiments	Methodology	YES
4365379	25834823	Jung-Lye Kim	PLoS52	designed research|conducted research	conducted research	Performed the experiments	Investigation	YES
4365379	25834823	Young-Hee Kang	PLoS52	designed research|wrote the paper|had primary responsibility for final content	designed research	Conceived and designed the experiments	Methodology	YES
4365379	25834823	Young-Hee Kang	PLoS52	designed research|wrote the paper|had primary responsibility for final content	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4365379	25834823	Young-Hee Kang	PLoS52	designed research|wrote the paper|had primary responsibility for final content	had primary responsibility for final content	-	-	NO
4942948	27411447	DR	2	carried out the experiments for the dna microarrays and data validation	carried out the experiments for the dna microarrays and data validation	Performed the experiments	Investigation|Validation	YES
4942948	27411447	EP	2	performed the phenotypic characterization	performed the phenotypic characterization	Performed the experiments	Investigation	YES
4942948	27411447	ER	2	carried out the experiments for the dna microarrays and data validation	carried out the experiments for the dna microarrays and data validation	Performed the experiments	Investigation|Validation	YES
4942948	27411447	GD	2	contributed with the performed microarray data analysis and functional annotation with the|performed the phenotypic characterization	contributed with the performed microarray data analysis and functional annotation with the	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Formal analysis|Investigation|Resources	YES
4942948	27411447	GD	2	contributed with the performed microarray data analysis and functional annotation with the|performed the phenotypic characterization	performed the phenotypic characterization	Performed the experiments	Investigation	YES
4942948	27411447	JA	2	performed microarray data analysis and functional annotation with the|helped with the wrote the manuscript with the	performed microarray data analysis and functional annotation with the	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
4942948	27411447	JA	2	performed microarray data analysis and functional annotation with the|helped with the wrote the manuscript with the	helped with the wrote the manuscript with the	Wrote the paper	Writing - Original Draft	YES
4942948	27411447	JC	2	carried out the experiments for the dna microarrays and data validation	carried out the experiments for the dna microarrays and data validation	Performed the experiments	Investigation|Validation	YES
4942948	27411447	JMRP	2	performed microarray data analysis and functional annotation with the|helped with the wrote the manuscript with the	performed microarray data analysis and functional annotation with the	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
4942948	27411447	JMRP	2	performed microarray data analysis and functional annotation with the|helped with the wrote the manuscript with the	helped with the wrote the manuscript with the	Wrote the paper	Writing - Original Draft	YES
4942948	27411447	LP	2	contributed with the performed microarray data analysis and functional annotation with the|wrote the manuscript with the	contributed with the performed microarray data analysis and functional annotation with the	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Formal analysis|Investigation|Resources	YES
4942948	27411447	LP	2	contributed with the performed microarray data analysis and functional annotation with the|wrote the manuscript with the	wrote the manuscript with the	Wrote the paper	Writing - Original Draft	YES
4942948	27411447	MAV	2	helped with the wrote the manuscript with the	helped with the wrote the manuscript with the	Wrote the paper	Writing - Original Draft	YES
4942948	27411447	PB	2	performed microarray data analysis and functional annotation with the	performed microarray data analysis and functional annotation with the	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
4942948	27411447	WF	2	designed and coordinated the isolation of the mutants|helped with the wrote the manuscript with the	designed and coordinated the isolation of the mutants	Conceived and designed the experiments|Performed the experiments	Investigation|Project administration	YES
4942948	27411447	WF	2	designed and coordinated the isolation of the mutants|helped with the wrote the manuscript with the	helped with the wrote the manuscript with the	Wrote the paper	Writing - Original Draft	YES
5330123	28265440	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5330123	28265440	DG	2	built parts of the cognitive battery and preformed the statistical analysis	built parts of the cognitive battery and preformed the statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5330123	28265440	DT	2	conceived of the study and participated in the design of the study and helped to draft the manuscript	conceived of the study and participated in the design of the study and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
5330123	28265440	IO	2	helped to draft the manuscript	helped to draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5330123	28265440	NG	2	built parts of the cognitive battery and wrote the methods part in the manuscript	built parts of the cognitive battery and wrote the methods part in the manuscript	Performed the experiments|Wrote the paper	Writing - Original Draft	YES
5330123	28265440	SG	2	carried out this study, participated in the sequence alignment and wrote the manuscript	carried out this study, participated in the sequence alignment and wrote the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5330124	28265453	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5330124	28265453	BJF	2	contributed to data analysis and interpretation, literature review, manuscript writing, critical revision and final approval	contributed to data analysis and interpretation, literature review, manuscript writing, critical revision and final approval	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5330124	28265453	DJD	2	contributed to study design, data collection, analysis and interpretation, critical revision and final approval	contributed to study design, data collection, analysis and interpretation, critical revision and final approval	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Review & Editing	YES
5330124	28265453	GCK	2	contributed to study design, data collection, analysis and interpretation, literature review, manuscript writing, critical revision and final approval	contributed to study design, data collection, analysis and interpretation, literature review, manuscript writing, critical revision and final approval	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5330124	28265453	HY	2	developed the fuzzy logic controller, contributed to study design, data collection, analysis and interpretation, literature review, manuscript writing, critical revision and final approval	developed the fuzzy logic controller, contributed to study design, data collection, analysis and interpretation, literature review, manuscript writing, critical revision and final approval	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5330124	28265453	MK	2	contributed to data analysis and interpretation, literature review, manuscript writing, critical revision and final approval	contributed to data analysis and interpretation, literature review, manuscript writing, critical revision and final approval	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5330124	28265453	MNK	2	contributed to data analysis and interpretation, critical revision and final approval	contributed to data analysis and interpretation, critical revision and final approval	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5330124	28265453	NRM	2	contributed to data analysis and interpretation, literature review, manuscript writing, critical revision and final approval	contributed to data analysis and interpretation, literature review, manuscript writing, critical revision and final approval	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5330124	28265453	Naval Research	2	during the time effort of this research project	during the time effort of this research project	-	-	NO
5330124	28265453	Resuscitation Solutions	2	is an incubator of medical technologies	is an incubator of medical technologies	-	-	NO
5330124	28265453	WJM	2	contributed to data analysis and interpretation, critical revision and final approval	contributed to data analysis and interpretation, critical revision and final approval	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4943003	27411385	C.V.	2	contributed to the study design	contributed to the study design	Conceived and designed the experiments	Methodology	YES
4943003	27411385	D.G.	2	contributed to the study design|developed the expression microarrays, and participated in the data analysis	contributed to the study design	Conceived and designed the experiments	Methodology	YES
4943003	27411385	D.G.	2	contributed to the study design|developed the expression microarrays, and participated in the data analysis	developed the expression microarrays, and participated in the data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4943003	27411385	F.B.	2	provided expertise, participated in the analysis of data, and the revision of the manuscript	provided expertise, participated in the analysis of data, and the revision of the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
4943003	27411385	J.L.M.	2	contributed to the study design|participated in the analysis of data, and wrote the manuscript	contributed to the study design	Conceived and designed the experiments	Methodology	YES
4943003	27411385	J.L.M.	2	contributed to the study design|participated in the analysis of data, and wrote the manuscript	participated in the analysis of data, and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4943003	27411385	M.R.O.	2	contributed to the study design|provided expertise, participated in the analysis of data, and the revision of the manuscript	contributed to the study design	Conceived and designed the experiments	Methodology	YES
4943003	27411385	M.R.O.	2	contributed to the study design|provided expertise, participated in the analysis of data, and the revision of the manuscript	provided expertise, participated in the analysis of data, and the revision of the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
4943003	27411385	R.L.S.	2	performed the bioinformatics analysis of data from genome sequencing and microarrays and participated in the revision of the manuscript	performed the bioinformatics analysis of data from genome sequencing and microarrays and participated in the revision of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
4943003	27411385	S.L.L.	2	participated in the development of the expression microarrays and in related data analysis	participated in the development of the expression microarrays and in related data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4943003	27411385	T.C.	2	contributed to the study design|performed the experimental work related to the selection and characterization of biocide mutants, participated in the analysis of phenotypic data, genomic and transcriptomics, and wrote the manuscript	contributed to the study design	Conceived and designed the experiments	Methodology	YES
4943003	27411385	T.C.	2	contributed to the study design|performed the experimental work related to the selection and characterization of biocide mutants, participated in the analysis of phenotypic data, genomic and transcriptomics, and wrote the manuscript	performed the experimental work related to the selection and characterization of biocide mutants, participated in the analysis of phenotypic data, genomic and transcriptomics, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4943003	27411385	T.M.C.	2	contributed to the study design|participated in the analysis of data, and wrote the manuscript	contributed to the study design	Conceived and designed the experiments	Methodology	YES
4943003	27411385	T.M.C.	2	contributed to the study design|participated in the analysis of data, and wrote the manuscript	participated in the analysis of data, and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5403905	28487712	BY	2	collected molecular and greenhouse data	collected molecular and greenhouse data	Performed the experiments	Investigation	YES
5403905	28487712	DL	2	collected molecular and greenhouse data	collected molecular and greenhouse data	Performed the experiments	Investigation	YES
5403905	28487712	HY	2	collected molecular and greenhouse data	collected molecular and greenhouse data	Performed the experiments	Investigation	YES
5403905	28487712	JY	2	helped with the analyzed the data with|assisted with the wrote the paper with the|revised and approved the final manuscript	helped with the analyzed the data with	Analyzed the data	Formal analysis	YES
5403905	28487712	JY	2	helped with the analyzed the data with|assisted with the wrote the paper with the|revised and approved the final manuscript	assisted with the wrote the paper with the	Wrote the paper	Writing - Original Draft	YES
5403905	28487712	JY	2	helped with the analyzed the data with|assisted with the wrote the paper with the|revised and approved the final manuscript	revised and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5403905	28487712	JZ	2	conceived the research and designed all experiments|assisted with the wrote the paper with the|revised and approved the final manuscript	conceived the research and designed all experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5403905	28487712	JZ	2	conceived the research and designed all experiments|assisted with the wrote the paper with the|revised and approved the final manuscript	assisted with the wrote the paper with the	Wrote the paper	Writing - Original Draft	YES
5403905	28487712	JZ	2	conceived the research and designed all experiments|assisted with the wrote the paper with the|revised and approved the final manuscript	revised and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5403905	28487712	LW	2	conceived the research and designed all experiments|collected molecular and greenhouse data|analyzed the data with|wrote the paper with the|revised and approved the final manuscript	conceived the research and designed all experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5403905	28487712	LW	2	conceived the research and designed all experiments|collected molecular and greenhouse data|analyzed the data with|wrote the paper with the|revised and approved the final manuscript	collected molecular and greenhouse data	Performed the experiments	Investigation	YES
5403905	28487712	LW	2	conceived the research and designed all experiments|collected molecular and greenhouse data|analyzed the data with|wrote the paper with the|revised and approved the final manuscript	analyzed the data with	Analyzed the data	Formal analysis	YES
5403905	28487712	LW	2	conceived the research and designed all experiments|collected molecular and greenhouse data|analyzed the data with|wrote the paper with the|revised and approved the final manuscript	wrote the paper with the	Wrote the paper	Writing - Original Draft	YES
5403905	28487712	LW	2	conceived the research and designed all experiments|collected molecular and greenhouse data|analyzed the data with|wrote the paper with the|revised and approved the final manuscript	revised and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5403905	28487712	SF	2	collected molecular and greenhouse data|helped with the analyzed the data with	collected molecular and greenhouse data	Performed the experiments	Investigation	YES
5403905	28487712	SF	2	collected molecular and greenhouse data|helped with the analyzed the data with	helped with the analyzed the data with	Analyzed the data	Formal analysis	YES
5403905	28487712	YL	2	collected molecular and greenhouse data|helped with the analyzed the data with|revised and approved the final manuscript	collected molecular and greenhouse data	Performed the experiments	Investigation	YES
5403905	28487712	YL	2	collected molecular and greenhouse data|helped with the analyzed the data with|revised and approved the final manuscript	helped with the analyzed the data with	Analyzed the data	Formal analysis	YES
5403905	28487712	YL	2	collected molecular and greenhouse data|helped with the analyzed the data with|revised and approved the final manuscript	revised and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4943476	27357396	All other authors	2	participated in the conception of the project and obtaining data	participated in the conception of the project and obtaining data	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
4943476	27357396	JP	2	performed the data analysis	performed the data analysis	Analyzed the data	Formal analysis	YES
4943476	27357396	JSKK	2	performed the data analysis	performed the data analysis	Analyzed the data	Formal analysis	YES
4943476	27357396	LS	2	performed the data analysis|annotated and analyzed the snps for significance and drafted the manuscript	performed the data analysis	Analyzed the data	Formal analysis	YES
4943476	27357396	LS	2	performed the data analysis|annotated and analyzed the snps for significance and drafted the manuscript	annotated and analyzed the snps for significance and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4943476	27357396	MB	2	performed the data analysis	performed the data analysis	Analyzed the data	Formal analysis	YES
4943476	27357396	ME	2	annotated and analyzed the snps for significance and drafted the manuscript	annotated and analyzed the snps for significance and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4943476	27357396	PGR	2	performed the data analysis	performed the data analysis	Analyzed the data	Formal analysis	YES
4943476	27357396	SP	2	performed the data analysis	performed the data analysis	Analyzed the data	Formal analysis	YES
5403916	28487713	AM	2	led field crews and collected field data	led field crews and collected field data	Performed the experiments	Investigation	YES
5403916	28487713	All authors	2	edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5403916	28487713	BC	2	conceived the idea|designed the experiment	conceived the idea	Conceived and designed the experiments	Conceptualization	YES
5403916	28487713	BC	2	conceived the idea|designed the experiment	designed the experiment	Conceived and designed the experiments	Methodology	YES
5403916	28487713	DA	2	conceived the idea	conceived the idea	Conceived and designed the experiments	Conceptualization	YES
5403916	28487713	DC	2	led field crews and collected field data	led field crews and collected field data	Performed the experiments	Investigation	YES
5403916	28487713	EC	2	conceived the idea	conceived the idea	Conceived and designed the experiments	Conceptualization	YES
5403916	28487713	JB	2	conceived the idea|led field crews and collected field data	conceived the idea	Conceived and designed the experiments	Conceptualization	YES
5403916	28487713	JB	2	conceived the idea|led field crews and collected field data	led field crews and collected field data	Performed the experiments	Investigation	YES
5403916	28487713	JL	2	led field crews and collected field data	led field crews and collected field data	Performed the experiments	Investigation	YES
5403916	28487713	JT	2	conducted uav data post-processing	conducted uav data post-processing	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5403916	28487713	NR	2	conceived the idea|designed the experiment	conceived the idea	Conceived and designed the experiments	Conceptualization	YES
5403916	28487713	NR	2	conceived the idea|designed the experiment	designed the experiment	Conceived and designed the experiments	Methodology	YES
5403916	28487713	SL	2	conceived the idea|designed the experiment|led field crews and collected field data|led all data analysis and manuscript writing	conceived the idea	Conceived and designed the experiments	Conceptualization	YES
5403916	28487713	SL	2	conceived the idea|designed the experiment|led field crews and collected field data|led all data analysis and manuscript writing	designed the experiment	Conceived and designed the experiments	Methodology	YES
5403916	28487713	SL	2	conceived the idea|designed the experiment|led field crews and collected field data|led all data analysis and manuscript writing	led field crews and collected field data	Performed the experiments	Investigation	YES
5403916	28487713	SL	2	conceived the idea|designed the experiment|led field crews and collected field data|led all data analysis and manuscript writing	led all data analysis and manuscript writing	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5330134	28265452	All authors	2	contributed to the drafting of the manuscript|read and approved the final manuscript	contributed to the drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
5330134	28265452	All authors	2	contributed to the drafting of the manuscript|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5330134	28265452	LS	2	contributed to the study design and analysis	contributed to the study design and analysis	Conceived and designed the experiments	Methodology	YES
5330134	28265452	Leah Shelef	2	had full access to all the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis	had full access to all the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis	Analyzed the data	Data curation|Formal analysis	YES
5330134	28265452	NY	2	contributed to the study design and analysis	contributed to the study design and analysis	Conceived and designed the experiments	Methodology	YES
5330134	28265452	Nirit Yavnai	2	had full access to all the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis	had full access to all the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis	Analyzed the data	Data curation|Formal analysis	YES
5330134	28265452	SG	2	contributed to the study design and analysis	contributed to the study design and analysis	Conceived and designed the experiments	Methodology	YES
5330134	28265452	Shirley Gordon	2	had full access to all the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis	had full access to all the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis	Analyzed the data	Data curation|Formal analysis	YES
5330134	28265452	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
4943479	27356971	GK	2	performed them|wrote the manuscript	performed them	Performed the experiments	Investigation	YES
4943479	27356971	GK	2	performed them|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4943479	27356971	MAT	2	provided the direction and guidance for the research	provided the direction and guidance for the research	-	Supervision	YES
5403918	28487715	All authors	2	have read and approved the final manuscript	have read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5403918	28487715	HC	2	participated in the preparation of the manuscript	participated in the preparation of the manuscript	Wrote the paper	Writing - Original Draft	YES
5403918	28487715	HZ	2	carried out part of material collection, rna extraction	carried out part of material collection, rna extraction	Performed the experiments	Investigation	YES
5403918	28487715	JG	2	carried out part of material collection, rna extraction	carried out part of material collection, rna extraction	Performed the experiments	Investigation	YES
5403918	28487715	ML	2	carried out part of material collection, rna extraction	carried out part of material collection, rna extraction	Performed the experiments	Investigation	YES
5403918	28487715	PY	2	wrote the draft of the paper	wrote the draft of the paper	Wrote the paper	Writing - Original Draft	YES
5403918	28487715	QW	2	conceived and designed the studies	conceived and designed the studies	Conceived and designed the experiments	Conceptualization|Methodology	YES
5403918	28487715	XZ	2	carried out part of material collection, rna extraction	carried out part of material collection, rna extraction	Performed the experiments	Investigation	YES
5403918	28487715	YC	2	participated in the preparation of the manuscript	participated in the preparation of the manuscript	Wrote the paper	Writing - Original Draft	YES
5330140	28265454	Both authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5330140	28265454	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
4943489	27357282	All other authors	2	participated in the conception of the project and obtaining data	participated in the conception of the project and obtaining data	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
4943489	27357282	DB	2	out the analyses	out the analyses	Analyzed the data	Formal analysis	YES
4943489	27357282	JSKK	2	out the analyses	out the analyses	Analyzed the data	Formal analysis	YES
4943489	27357282	LS	2	out the analyses|annotated and analyzed the snps for significance and drafted the manuscript	out the analyses	Analyzed the data	Formal analysis	YES
4943489	27357282	LS	2	out the analyses|annotated and analyzed the snps for significance and drafted the manuscript	annotated and analyzed the snps for significance and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4943489	27357282	MD	2	out the analyses	out the analyses	Analyzed the data	Formal analysis	YES
4943489	27357282	ME	2	annotated and analyzed the snps for significance and drafted the manuscript	annotated and analyzed the snps for significance and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4943489	27357282	PGR	2	out the analyses	out the analyses	Analyzed the data	Formal analysis	YES
4943503	27357110	All other authors	2	participated in the conception of the project and obtaining data	participated in the conception of the project and obtaining data	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
4943503	27357110	JSKK	2	carried out data analysis	carried out data analysis	Analyzed the data	Formal analysis	YES
4943503	27357110	LS	2	carried out data analysis|annotated and analyzed the snps for significance and drafted the manuscript	carried out data analysis	Analyzed the data	Formal analysis	YES
4943503	27357110	LS	2	carried out data analysis|annotated and analyzed the snps for significance and drafted the manuscript	annotated and analyzed the snps for significance and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4943503	27357110	MB	2	carried out data analysis	carried out data analysis	Analyzed the data	Formal analysis	YES
4943503	27357110	ME	2	annotated and analyzed the snps for significance and drafted the manuscript	annotated and analyzed the snps for significance and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4943503	27357110	SP	2	carried out data analysis	carried out data analysis	Analyzed the data	Formal analysis	YES
5403927	28487711	AK	2	conceptualized the idea and supervised all the experiments|critically read the manuscript and provided valuable inputs	conceptualized the idea and supervised all the experiments	Conceived and designed the experiments	Conceptualization|Supervision	YES
5403927	28487711	AK	2	conceptualized the idea and supervised all the experiments|critically read the manuscript and provided valuable inputs	critically read the manuscript and provided valuable inputs	-	-	NO
5403927	28487711	DP	2	critically read the manuscript and provided valuable inputs	critically read the manuscript and provided valuable inputs	-	-	NO
5403927	28487711	GT	2	critically read the manuscript and provided valuable inputs	critically read the manuscript and provided valuable inputs	-	-	NO
5403927	28487711	MB	2	critically read the manuscript and provided valuable inputs	critically read the manuscript and provided valuable inputs	-	-	NO
5403927	28487711	RKP	2	performed all the experiments, interpreted the results and formulated the manuscript	performed all the experiments, interpreted the results and formulated the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation	YES
5403927	28487711	RS	2	critically read the manuscript and provided valuable inputs	critically read the manuscript and provided valuable inputs	-	-	NO
5403927	28487711	all authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5330142	28265439	AA	2	collected the data|designed the article, and drafted the manuscript|performed the statistical analysis	collected the data	Performed the experiments	Investigation	YES
5330142	28265439	AA	2	collected the data|designed the article, and drafted the manuscript|performed the statistical analysis	designed the article, and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
5330142	28265439	AA	2	collected the data|designed the article, and drafted the manuscript|performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
5330142	28265439	AF	2	helped to draft the manuscript	helped to draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5330142	28265439	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5330142	28265439	LS	2	collected the data|designed the article, and drafted the manuscript|performed the statistical analysis	collected the data	Performed the experiments	Investigation	YES
5330142	28265439	LS	2	collected the data|designed the article, and drafted the manuscript|performed the statistical analysis	designed the article, and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
5330142	28265439	LS	2	collected the data|designed the article, and drafted the manuscript|performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
5330142	28265439	NY	2	performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
5330142	28265439	OS	2	designed the article, and drafted the manuscript|performed the statistical analysis	designed the article, and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
5330142	28265439	OS	2	designed the article, and drafted the manuscript|performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
4369886	25839032	Chao Wang	2	as the first authors contributed equally to this paper	as the first authors contributed equally to this paper	-	-	NO
4369886	25839032	Chunfang Liu	2	as the first authors contributed equally to this paper	as the first authors contributed equally to this paper	-	-	NO
4943516	27357204	AAH	2	assisted in project design, data analysis, and preparation of the manuscript	assisted in project design, data analysis, and preparation of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4943516	27357204	CDC	2	assisted in data collection and manuscript preparation	assisted in data collection and manuscript preparation	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4943516	27357204	JSKK	2	assisted in data collection, project design, data analysis, and preparation of the manuscript	assisted in data collection, project design, data analysis, and preparation of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4943516	27357204	JTT	2	assisted in data collection and manuscript preparation	assisted in data collection and manuscript preparation	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4943516	27357204	MCN	2	assisted in data collection and manuscript preparation	assisted in data collection and manuscript preparation	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4943516	27357204	MTWE	2	assisted in project design, data analysis, and preparation of the manuscript	assisted in project design, data analysis, and preparation of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4943516	27357204	RGM	2	assisted in data collection and manuscript preparation	assisted in data collection and manuscript preparation	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5403931	28487714	DS	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5403931	28487714	JD	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5403931	28487714	JL	PLoS52	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5403931	28487714	JZ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5403931	28487714	KH	PLoS52	designed the experiments|analyzed the data and wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5403931	28487714	KH	PLoS52	designed the experiments|analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5403931	28487714	SZ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5403931	28487714	YG	PLoS52	designed the experiments|performed the experiments|analyzed the data and wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5403931	28487714	YG	PLoS52	designed the experiments|performed the experiments|analyzed the data and wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5403931	28487714	YG	PLoS52	designed the experiments|performed the experiments|analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5403931	28487714	YW	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5403931	28487714	YZ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5330147	28265436	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5330147	28265436	DNJ	2	participated in the study design and acquisition of the data	participated in the study design and acquisition of the data	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5330147	28265436	HURTE	2	scores  to evaluate the symptoms of post-traumatic stress|scores  for the symptoms of post-traumatic stress and study design	scores  to evaluate the symptoms of post-traumatic stress	-	-	NO
5330147	28265436	HURTE	2	scores  to evaluate the symptoms of post-traumatic stress|scores  for the symptoms of post-traumatic stress and study design	scores  for the symptoms of post-traumatic stress and study design	Conceived and designed the experiments	Methodology	YES
5330147	28265436	JS	2	participated in the design and coordination of this study and helped to draft the manuscript	participated in the design and coordination of this study and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft	YES
5330147	28265436	JT	2	participated in the data analysis and interpretation of the data	participated in the data analysis and interpretation of the data	Analyzed the data	Formal analysis	YES
5330147	28265436	RH	2	participated in the conception, design and coordination of this study and revising it critically for important intellectual content	participated in the conception, design and coordination of this study and revising it critically for important intellectual content	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Review & Editing	YES
5330147	28265436	VR	2	participated in the design of the study, performed the statistical analysis and drafted the manuscript	participated in the design of the study, performed the statistical analysis and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4947262	27423334	ALH	PLoS52	conceived and planned the project|performed the experiments|are joint first authors|wrote the manuscript and all authors reviewed it	conceived and planned the project	Conceived and designed the experiments	Conceptualization	YES
4947262	27423334	ALH	PLoS52	conceived and planned the project|performed the experiments|are joint first authors|wrote the manuscript and all authors reviewed it	performed the experiments	Performed the experiments	Investigation	YES
4947262	27423334	ALH	PLoS52	conceived and planned the project|performed the experiments|are joint first authors|wrote the manuscript and all authors reviewed it	are joint first authors	-	-	NO
4947262	27423334	ALH	PLoS52	conceived and planned the project|performed the experiments|are joint first authors|wrote the manuscript and all authors reviewed it	wrote the manuscript and all authors reviewed it	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4947262	27423334	CNM	PLoS52	conceived and planned the project|performed the experiments|are joint first authors|wrote the manuscript and all authors reviewed it	conceived and planned the project	Conceived and designed the experiments	Conceptualization	YES
4947262	27423334	CNM	PLoS52	conceived and planned the project|performed the experiments|are joint first authors|wrote the manuscript and all authors reviewed it	performed the experiments	Performed the experiments	Investigation	YES
4947262	27423334	CNM	PLoS52	conceived and planned the project|performed the experiments|are joint first authors|wrote the manuscript and all authors reviewed it	are joint first authors	-	-	NO
4947262	27423334	CNM	PLoS52	conceived and planned the project|performed the experiments|are joint first authors|wrote the manuscript and all authors reviewed it	wrote the manuscript and all authors reviewed it	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4947262	27423334	IB	PLoS52	conceived and planned the project|wrote the manuscript and all authors reviewed it	conceived and planned the project	Conceived and designed the experiments	Conceptualization	YES
4947262	27423334	IB	PLoS52	conceived and planned the project|wrote the manuscript and all authors reviewed it	wrote the manuscript and all authors reviewed it	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4947262	27423334	KW	PLoS52	conceived and planned the project	conceived and planned the project	Conceived and designed the experiments	Conceptualization	YES
4947262	27423334	MT	PLoS52	performed data analysis	performed data analysis	Analyzed the data	Formal analysis	YES
4947262	27423334	PW	PLoS52	planned and supervised field trials	planned and supervised field trials	Conceived and designed the experiments	Conceptualization|Supervision	YES
5403933	28487708	BD	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5403933	28487708	IT	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
5403933	28487708	IT	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5403933	28487708	IT	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5403933	28487708	JB	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5403933	28487708	KR	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
5403933	28487708	KR	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5403933	28487708	KR	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5403933	28487708	TS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5403933	28487708	TS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5403933	28487708	VS	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5330161	28265450	All	2	data and materials can be reproducible	data and materials can be reproducible	-	-	NO
5330161	28265450	S. All	2	authors read and approved the final manuscript	authors read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5330161	28265450	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5403939	28487707	BG	2	performed the statistical analysis|wrote the manuscript	performed the statistical analysis	Analyzed the data	Formal analysis	YES
5403939	28487707	BG	2	performed the statistical analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5403939	28487707	FL	2	critically revised it	critically revised it	Wrote the paper	Writing - Review & Editing	YES
5403939	28487707	HvV	2	performed the statistical analysis|critically revised it	performed the statistical analysis	Analyzed the data	Formal analysis	YES
5403939	28487707	HvV	2	performed the statistical analysis|critically revised it	critically revised it	Wrote the paper	Writing - Review & Editing	YES
5403939	28487707	PP	2	critically revised it	critically revised it	Wrote the paper	Writing - Review & Editing	YES
4952276	27435615	AJ	7	Idea, implementation, testing, interpretation, and writing	Idea, implementation, testing, interpretation, and writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation	YES
4952276	27435615	NP	7	Idea, interpretation, and writing	Idea, interpretation, and writing	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis	YES
5385021	28405348	All authors	2	contributed to the drafting and editing of the manuscript|read and approved the final manuscript	contributed to the drafting and editing of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5385021	28405348	All authors	2	contributed to the drafting and editing of the manuscript|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5385021	28405348	MN	2	analyzed the acquired data	analyzed the acquired data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5385021	28405348	NH	2	developed software for voice emotion analysis	developed software for voice emotion analysis	Contributed reagents/materials/analysis tools	Software	YES
5385021	28405348	SM	2	invented the method of voice emotion analysis and the algorithm of vocal affect display used in this work	invented the method of voice emotion analysis and the algorithm of vocal affect display used in this work	Performed the experiments|Contributed reagents/materials/analysis tools	Software	YES
5385021	28405348	SS	2	developed software for voice emotion analysis	developed software for voice emotion analysis	Contributed reagents/materials/analysis tools	Software	YES
5385021	28405348	ST	2	designed the protocol of voice acquisition and managed the voice acquisition	designed the protocol of voice acquisition and managed the voice acquisition	Conceived and designed the experiments	Methodology	YES
5385021	28405348	The authors	2	declare that they have no competing interests|acquired oral consent from the participants	declare that they have no competing interests	-	-	NO
5385021	28405348	The authors	2	declare that they have no competing interests|acquired oral consent from the participants	acquired oral consent from the participants	-	-	NO
5385021	28405348	YO	2	developed software for voice emotion analysis	developed software for voice emotion analysis	Contributed reagents/materials/analysis tools	Software	YES
5403951	28487706	GS	2	carried out the qpcr analysis	carried out the qpcr analysis	Performed the experiments	Investigation	YES
5403951	28487706	IA	2	conceived the study|discussed the results and wrote the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5403951	28487706	IA	2	conceived the study|discussed the results and wrote the manuscript	discussed the results and wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5403951	28487706	JF	2	conceived the study|performed the speciation rate shifts analysis|discussed the results and wrote the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5403951	28487706	JF	2	conceived the study|performed the speciation rate shifts analysis|discussed the results and wrote the manuscript	performed the speciation rate shifts analysis	Performed the experiments	Investigation	YES
5403951	28487706	JF	2	conceived the study|performed the speciation rate shifts analysis|discussed the results and wrote the manuscript	discussed the results and wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5403951	28487706	MB	2	conceived the study|performed phylogenetic analyses|conducted the in situ hybridization|carried out the qpcr analysis|discussed the results and wrote the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5403951	28487706	MB	2	conceived the study|performed phylogenetic analyses|conducted the in situ hybridization|carried out the qpcr analysis|discussed the results and wrote the manuscript	performed phylogenetic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5403951	28487706	MB	2	conceived the study|performed phylogenetic analyses|conducted the in situ hybridization|carried out the qpcr analysis|discussed the results and wrote the manuscript	conducted the in situ hybridization	Performed the experiments	Investigation	YES
5403951	28487706	MB	2	conceived the study|performed phylogenetic analyses|conducted the in situ hybridization|carried out the qpcr analysis|discussed the results and wrote the manuscript	carried out the qpcr analysis	Performed the experiments	Investigation	YES
5403951	28487706	MB	2	conceived the study|performed phylogenetic analyses|conducted the in situ hybridization|carried out the qpcr analysis|discussed the results and wrote the manuscript	discussed the results and wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5403951	28487706	PC	2	conceived the study|conducted the in situ hybridization|discussed the results and wrote the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5403951	28487706	PC	2	conceived the study|conducted the in situ hybridization|discussed the results and wrote the manuscript	conducted the in situ hybridization	Performed the experiments	Investigation	YES
5403951	28487706	PC	2	conceived the study|conducted the in situ hybridization|discussed the results and wrote the manuscript	discussed the results and wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4955149	27444955	AIV	2	wrote the scripts and carried out the analysis	wrote the scripts and carried out the analysis	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Software|Writing - Original Draft	YES
4955149	27444955	OEG	2	designed the study|has supervised the whole implementation and paper writing	designed the study	Conceived and designed the experiments	Methodology	YES
4955149	27444955	OEG	2	designed the study|has supervised the whole implementation and paper writing	has supervised the whole implementation and paper writing	Performed the experiments|Wrote the paper	Investigation|Supervision	YES
5577774	28861275	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5577774	28861275	RK	2	drafted the manuscript and reviewed for grammar and syntax	drafted the manuscript and reviewed for grammar and syntax	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5577774	28861275	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5577774	28861275	UA	2	collected the clinical data and facilitated with drafting of the manuscript	collected the clinical data and facilitated with drafting of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4957382	27448633	GS	1	Principal investigator	Principal investigator	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
5404147	28487701	AWK	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5404147	28487701	DD	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5404147	28487701	GA	PLoS52	performed the experiments|with support of rkv wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5404147	28487701	GA	PLoS52	performed the experiments|with support of rkv wrote the manuscript	with support of rkv wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5404147	28487701	HK	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5404147	28487701	LTP	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5404147	28487701	MS	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5404147	28487701	PBK	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5404147	28487701	RKV	PLoS52	conceived and designed the experiment	conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5404147	28487701	SNN	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5404147	28487701	VG	PLoS52	performed the experiments|analyzed the data|with support of rkv wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5404147	28487701	VG	PLoS52	performed the experiments|analyzed the data|with support of rkv wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5404147	28487701	VG	PLoS52	performed the experiments|analyzed the data|with support of rkv wrote the manuscript	with support of rkv wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5704384	29209509	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5704384	29209509	All the authors	2	have contributed towards the design of study, collection, analysis and interpretation of data	have contributed towards the design of study, collection, analysis and interpretation of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Methodology|Resources	YES
5704384	29209509	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5404177	28487703	EK	2	designed the study|carried out the experiments|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5404177	28487703	EK	2	designed the study|carried out the experiments|wrote the manuscript	carried out the experiments	Performed the experiments	Investigation	YES
5404177	28487703	EK	2	designed the study|carried out the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5404177	28487703	ES	2	designed the study|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5404177	28487703	ES	2	designed the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5404177	28487703	MC-G	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5404177	28487703	SM	2	produced and provided data	produced and provided data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4377353	25861619	Aitian Yin	2	contributed in conception, design, revising paper, and final approval	contributed in conception, design, revising paper, and final approval	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
4377353	25861619	Elizabeth Maitland	2	contributed in conception, design, revising paper, and final approval	contributed in conception, design, revising paper, and final approval	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
4377353	25861619	Leiyu Shi	2	contributed in conception, design, drafting of paper, revising paper, and final approval	contributed in conception, design, drafting of paper, revising paper, and final approval	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
4377353	25861619	Stephen Nicholas	2	contributed in conception, design, revising paper, and final approval	contributed in conception, design, revising paper, and final approval	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
4377353	25861619	Wenhua Wang	2	contributed in conception, design, acquisition of data, analysis and interpretation of data, drafting of paper, revising paper, and final approval	contributed in conception, design, acquisition of data, analysis and interpretation of data, drafting of paper, revising paper, and final approval	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
4377353	25861619	Xiaoyun Liu	2	contributed in conception, design, analysis and interpretation of data, revising paper, and final approval	contributed in conception, design, analysis and interpretation of data, revising paper, and final approval	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Resources|Writing - Review & Editing	YES
4377353	25861619	Zongfu Mao	2	contributed in conception, design, acquisition of data, revising paper, and final approval	contributed in conception, design, acquisition of data, revising paper, and final approval	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Investigation|Resources|Writing - Review & Editing	YES
4377357	25861635	Erbao Ruan	2	performed the research	performed the research	Performed the experiments	Investigation	YES
4377357	25861635	Guojin Wang	2	performed the research	performed the research	Performed the experiments	Investigation	YES
4377357	25861635	Hong Liu	2	performed the research	performed the research	Performed the experiments	Investigation	YES
4377357	25861635	Huaquan Wang	2	contributed equally to this study|designed the research study, analyzed the data, and wrote the paper	contributed equally to this study	-	-	NO
4377357	25861635	Huaquan Wang	2	contributed equally to this study|designed the research study, analyzed the data, and wrote the paper	designed the research study, analyzed the data, and wrote the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4377357	25861635	Jia Song	2	performed the research	performed the research	Performed the experiments	Investigation	YES
4377357	25861635	Jing Guan	2	performed the research	performed the research	Performed the experiments	Investigation	YES
4377357	25861635	Lijuan Li	2	performed the research	performed the research	Performed the experiments	Investigation	YES
4377357	25861635	Limin Xing	2	performed the research	performed the research	Performed the experiments	Investigation	YES
4377357	25861635	Qie Dong	2	contributed equally to this study|performed the research	contributed equally to this study	-	-	NO
4377357	25861635	Qie Dong	2	contributed equally to this study|performed the research	performed the research	Performed the experiments	Investigation	YES
4377357	25861635	Rong Fu	2	performed the research	performed the research	Performed the experiments	Investigation	YES
4377357	25861635	Wen Qu	2	performed the research	performed the research	Performed the experiments	Investigation	YES
4377357	25861635	Yuhong Wu	2	performed the research	performed the research	Performed the experiments	Investigation	YES
4377357	25861635	Zonghong Shao	2	designed the research study, analyzed the data, and wrote the paper	designed the research study, analyzed the data, and wrote the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5404178	28487702	CY	1	Field and lab work	Field and lab work	Performed the experiments	Investigation	YES
5404178	28487702	FY	1	Data analysis	Data analysis	Analyzed the data	Formal analysis	YES
5404178	28487702	JD	1	Field and lab work|Paper concept and writing	Field and lab work	Performed the experiments	Investigation	YES
5404178	28487702	JD	1	Field and lab work|Paper concept and writing	Paper concept and writing	Conceived and designed the experiments|Wrote the paper	Conceptualization	YES
5404178	28487702	JL	1	Study idea and design|Paper concept and writing	Study idea and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5404178	28487702	JL	1	Study idea and design|Paper concept and writing	Paper concept and writing	Conceived and designed the experiments|Wrote the paper	Conceptualization	YES
5404178	28487702	JZ	1	Field and lab work	Field and lab work	Performed the experiments	Investigation	YES
5404178	28487702	QZ	1	Data analysis	Data analysis	Analyzed the data	Formal analysis	YES
5404178	28487702	WY	1	Study idea and design	Study idea and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4377360	25861643	Cen Zhang	2	carried out cell experiment, data collection and analysis, and paper submission	carried out cell experiment, data collection and analysis, and paper submission	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4377360	25861643	Min Hu	2	carried out cell experiment, data collection and analysis, and paper submission	carried out cell experiment, data collection and analysis, and paper submission	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4377360	25861643	Shuo Huang	2	carried out cell experiment, data collection and analysis, and paper submission	carried out cell experiment, data collection and analysis, and paper submission	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4377360	25861643	Tao Peng	2	carried out the study design and paper drafting	carried out the study design and paper drafting	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
4377360	25861643	Ting-TingWu	2	carried out cell experiment, data collection and analysis, and paper submission	carried out cell experiment, data collection and analysis, and paper submission	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4377360	25861643	Xu-Hong Zhou	2	carried out the study design and paper drafting	carried out the study design and paper drafting	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
4377360	25861643	Zhe Chen	2	carried out cell experiment, data collection and analysis, and paper submission	carried out cell experiment, data collection and analysis, and paper submission	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4377361	25861627	Lingyun Zhu	2	contributed equally to this work	contributed equally to this work	-	-	NO
4377361	25861627	Zhishan Xu	2	contributed equally to this work	contributed equally to this work	-	-	NO
5404181	28487716	AB-M	2	conceived and designed the work|performed network analyses|wrote the first draft of the manuscript, to which all authors contributed	conceived and designed the work	Conceived and designed the experiments	Conceptualization	YES
5404181	28487716	AB-M	2	conceived and designed the work|performed network analyses|wrote the first draft of the manuscript, to which all authors contributed	performed network analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5404181	28487716	AB-M	2	conceived and designed the work|performed network analyses|wrote the first draft of the manuscript, to which all authors contributed	wrote the first draft of the manuscript, to which all authors contributed	Wrote the paper	Writing - Original Draft	YES
5404181	28487716	CV-C	2	performed network analyses	performed network analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5404181	28487716	FR-C	2	constructed the co-expression networks	constructed the co-expression networks	Performed the experiments	Investigation	YES
5404181	28487716	FV	2	constructed the co-expression networks	constructed the co-expression networks	Performed the experiments	Investigation	YES
5404181	28487716	JH-G	2	conceived and designed the work|performed network analyses	conceived and designed the work	Conceived and designed the experiments	Conceptualization	YES
5404181	28487716	JH-G	2	conceived and designed the work|performed network analyses	performed network analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5404181	28487716	JR	2	constructed the co-expression networks	constructed the co-expression networks	Performed the experiments	Investigation	YES
5404181	28487716	MB	2	conceived and designed the work|wrote the first draft of the manuscript, to which all authors contributed	conceived and designed the work	Conceived and designed the experiments	Conceptualization	YES
5404181	28487716	MB	2	conceived and designed the work|wrote the first draft of the manuscript, to which all authors contributed	wrote the first draft of the manuscript, to which all authors contributed	Wrote the paper	Writing - Original Draft	YES
5404182	28487719	AG-M	2	contributed to evaluation and discussion regarding aspects of the study related to gene expression analyses	contributed to evaluation and discussion regarding aspects of the study related to gene expression analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5404182	28487719	All authors	2	contributed to the discussion and approved the final manuscript	contributed to the discussion and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5404182	28487719	HJ	2	contributed to evaluation and discussion regarding aspects of the study related to gene expression analyses	contributed to evaluation and discussion regarding aspects of the study related to gene expression analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5404182	28487719	KG	2	assisted with management and analysis of the flow cytometry and laser scanning clsm data	assisted with management and analysis of the flow cytometry and laser scanning clsm data	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5404182	28487719	PC	2	conceived the idea and wrote the manuscript|supervised the research	conceived the idea and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5404182	28487719	PC	2	conceived the idea and wrote the manuscript|supervised the research	supervised the research	-	Supervision	YES
5404182	28487719	SP	2	conceived the idea and wrote the manuscript	conceived the idea and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4962366	27461489	A.T.	2	carried out larvae sampling, cortisol measurements and animal performance experiments and prepared figs	carried out larvae sampling, cortisol measurements and animal performance experiments and prepared figs	Performed the experiments	Investigation|Visualization	YES
4962366	27461489	All authors	2	reviewed and approved the manuscript	reviewed and approved the manuscript	Wrote the paper	Writing - Review & Editing	YES
4962366	27461489	E.S.	2	conceived and wrote the main manuscript text and performed ngs meta analysis	conceived and wrote the main manuscript text and performed ngs meta analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
4962366	27461489	M.P.	2	coordinated and designed the study as well as contributed to writing	coordinated and designed the study as well as contributed to writing	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration	YES
4377370	25861626	Isaac Perea-Gil	2	contributed equally to this work	contributed equally to this work	-	-	NO
4377370	25861626	Marta Monguio-Tortajada	2	contributed equally to this work	contributed equally to this work	-	-	NO
4964045	27464550	PAA	2	conceived of the study, participated in its design and coordination and helped to draft the manuscript	conceived of the study, participated in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
4964045	27464550	XGC	2	participated in the design of the study and the analysis of the data	participated in the design of the study and the analysis of the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
4964045	27464550	XH	2	designed the study, performed the assemblies, assessed the quality of the assemblies and drafted the manuscript	designed the study, performed the assemblies, assessed the quality of the assemblies and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Validation|Writing - Original Draft	YES
5404183	28487722	CW	7	carried out the genetic studies|helped to revise the manuscript	carried out the genetic studies	Performed the experiments	Investigation	YES
5404183	28487722	CW	7	carried out the genetic studies|helped to revise the manuscript	helped to revise the manuscript	Wrote the paper	Writing - Review & Editing	YES
5404183	28487722	HY	7	managed the materials	managed the materials	-	-	NO
5404183	28487722	MZ	7	designed the research experiments|performed the phenotyping|analyzed the data and drafted the manuscript	designed the research experiments	Conceived and designed the experiments	Methodology	YES
5404183	28487722	MZ	7	designed the research experiments|performed the phenotyping|analyzed the data and drafted the manuscript	performed the phenotyping	Performed the experiments	Investigation	YES
5404183	28487722	MZ	7	designed the research experiments|performed the phenotyping|analyzed the data and drafted the manuscript	analyzed the data and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5404183	28487722	QL	7	designed the research experiments|performed the phenotyping|analyzed the data and drafted the manuscript	designed the research experiments	Conceived and designed the experiments	Methodology	YES
5404183	28487722	QL	7	designed the research experiments|performed the phenotyping|analyzed the data and drafted the manuscript	performed the phenotyping	Performed the experiments	Investigation	YES
5404183	28487722	QL	7	designed the research experiments|performed the phenotyping|analyzed the data and drafted the manuscript	analyzed the data and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5404183	28487722	QX	7	carried out the genetic studies	carried out the genetic studies	Performed the experiments	Investigation	YES
5404183	28487722	SW	7	helped to revise the manuscript	helped to revise the manuscript	Wrote the paper	Writing - Review & Editing	YES
5404183	28487722	WW	7	managed the materials	managed the materials	-	-	NO
5404183	28487722	XN	7	performed the phenotyping	performed the phenotyping	Performed the experiments	Investigation	YES
5404183	28487722	XW	7	designed the research experiments|designed the overall project	designed the research experiments	Conceived and designed the experiments	Methodology	YES
5404183	28487722	XW	7	designed the research experiments|designed the overall project	designed the overall project	Conceived and designed the experiments	Methodology	YES
5404183	28487722	XY	7	managed the materials	managed the materials	-	-	NO
5404183	28487722	YF	7	carried out the genetic studies	carried out the genetic studies	Performed the experiments	Investigation	YES
5404183	28487722	YW	7	managed the materials	managed the materials	-	-	NO
4377373	25861641	Each author	2	has participated sufficiently, intellectually or practically, in the work to take public responsibility for the content of the paper	has participated sufficiently, intellectually or practically, in the work to take public responsibility for the content of the paper	-	-	NO
4966569	27472913	AA	2	supervised the study|wrote the manuscript with contributions from all co-authors	supervised the study	-	Supervision	YES
4966569	27472913	AA	2	supervised the study|wrote the manuscript with contributions from all co-authors	wrote the manuscript with contributions from all co-authors	Wrote the paper	Writing - Original Draft	YES
4966569	27472913	All authors	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
4966569	27472913	BA	2	contributed to elaborate analysis tools|supervised the study	contributed to elaborate analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4966569	27472913	BA	2	contributed to elaborate analysis tools|supervised the study	supervised the study	-	Supervision	YES
4966569	27472913	FA	2	contributed to elaborate analysis tools|supervised the study	contributed to elaborate analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4966569	27472913	FA	2	contributed to elaborate analysis tools|supervised the study	supervised the study	-	Supervision	YES
4966569	27472913	GD	2	performed the analysis	performed the analysis	Performed the experiments	Investigation	YES
5404241	28487704	AJ	PLoS5	Performed experiments|Analyzed the data|Wrote the paper	Performed experiments	Performed the experiments	Investigation	YES
5404241	28487704	AJ	PLoS5	Performed experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5404241	28487704	AJ	PLoS5	Performed experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5404241	28487704	AS	PLoS5	Conceived and designed experiments	Conceived and designed experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5404241	28487704	IH	PLoS5	Performed experiments|Analyzed the data|Wrote the paper	Performed experiments	Performed the experiments	Investigation	YES
5404241	28487704	IH	PLoS5	Performed experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5404241	28487704	IH	PLoS5	Performed experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5404241	28487704	KA	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5404241	28487704	LP	PLoS5	Performed experiments	Performed experiments	Performed the experiments	Investigation	YES
5404241	28487704	MC	PLoS5	Performed experiments	Performed experiments	Performed the experiments	Investigation	YES
5404241	28487704	MV	PLoS5	Performed experiments	Performed experiments	Performed the experiments	Investigation	YES
5404241	28487704	OT	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5404241	28487704	OT	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5404241	28487704	PB	PLoS5	Conceived and designed experiments|Analyzed the data	Conceived and designed experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5404241	28487704	PB	PLoS5	Conceived and designed experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5404241	28487704	PH	PLoS5	Conceived and designed experiments|Performed experiments|Wrote the paper	Conceived and designed experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5404241	28487704	PH	PLoS5	Conceived and designed experiments|Performed experiments|Wrote the paper	Performed experiments	Performed the experiments	Investigation	YES
5404241	28487704	PH	PLoS5	Conceived and designed experiments|Performed experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5404241	28487704	PS	PLoS5	Conceived and designed experiments|Performed experiments|Wrote the paper	Conceived and designed experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5404241	28487704	PS	PLoS5	Conceived and designed experiments|Performed experiments|Wrote the paper	Performed experiments	Performed the experiments	Investigation	YES
5404241	28487704	PS	PLoS5	Conceived and designed experiments|Performed experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5404265	28487721	HX	2	conducted the experiments	conducted the experiments	Performed the experiments	Investigation	YES
5404265	28487721	JM	2	designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
5404265	28487721	LX	2	conducted the experiments|analyzed the data and wrote the manuscript	conducted the experiments	Performed the experiments	Investigation	YES
5404265	28487721	LX	2	conducted the experiments|analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5404265	28487721	PY	2	conducted the experiments	conducted the experiments	Performed the experiments	Investigation	YES
5404265	28487721	SY	2	conducted the experiments	conducted the experiments	Performed the experiments	Investigation	YES
5404265	28487721	YC	2	conducted the experiments	conducted the experiments	Performed the experiments	Investigation	YES
5404265	28487721	YF	2	conducted the experiments	conducted the experiments	Performed the experiments	Investigation	YES
5404265	28487721	YT	2	conducted the experiments	conducted the experiments	Performed the experiments	Investigation	YES
4966751	27474039	AN	2	conceived the study and revised the manuscript	conceived the study and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
4966751	27474039	GS	2	participated in the design of the study, carried out statistical and bioinformatic analyses and drafted the manuscript	participated in the design of the study, carried out statistical and bioinformatic analyses and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4966751	27474039	MLV	2	participated in the design of the study, carried out statistical analyses and drafted the manuscript	participated in the design of the study, carried out statistical analyses and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4966751	27474039	NP	2	participated in the design of the study and carried out statistical analyses	participated in the design of the study and carried out statistical analyses	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
4966751	27474039	YEP	2	conceived, designed and coordinated the study, and drafted the manuscript	conceived, designed and coordinated the study, and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
5404360	28487717	C-YL	2	performed the experiment	performed the experiment	Performed the experiments	Investigation	YES
5404360	28487717	LY	2	designed the study and wrote the manuscript|performed the experiment	designed the study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5404360	28487717	LY	2	designed the study and wrote the manuscript|performed the experiment	performed the experiment	Performed the experiments	Investigation	YES
5404360	28487717	M-YC	2	performed the experiment	performed the experiment	Performed the experiments	Investigation	YES
5404360	28487717	X-YC	2	helped in data analysis and manuscript preparation	helped in data analysis and manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5404360	28487717	XF	2	designed the study and wrote the manuscript	designed the study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5404360	28487717	YY	2	performed the experiment	performed the experiment	Performed the experiments	Investigation	YES
4773028	26941993	C.-S.Y.	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4773028	26941993	C.-Z.W.	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4773028	26941993	S.A.	2	edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
4773028	26941993	Y.C.	2	edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5404384	28487710	CJ	2	coordinated the logistics for fieldwork experiments|performed the ethylene experiments and collected samples for rna isolation and histological studies|performed the qpcr analysis	coordinated the logistics for fieldwork experiments	Performed the experiments	Investigation|Project administration	YES
5404384	28487710	CJ	2	coordinated the logistics for fieldwork experiments|performed the ethylene experiments and collected samples for rna isolation and histological studies|performed the qpcr analysis	performed the ethylene experiments and collected samples for rna isolation and histological studies	Performed the experiments	Investigation	YES
5404384	28487710	CJ	2	coordinated the logistics for fieldwork experiments|performed the ethylene experiments and collected samples for rna isolation and histological studies|performed the qpcr analysis	performed the qpcr analysis	Performed the experiments	Investigation	YES
5404384	28487710	FM	2	devised and participated in all aspects of the study|performed the ethylene experiments and collected samples for rna isolation and histological studies|performed the qpcr analysis|participated in writing the article	devised and participated in all aspects of the study	Conceived and designed the experiments	Conceptualization	YES
5404384	28487710	FM	2	devised and participated in all aspects of the study|performed the ethylene experiments and collected samples for rna isolation and histological studies|performed the qpcr analysis|participated in writing the article	performed the ethylene experiments and collected samples for rna isolation and histological studies	Performed the experiments	Investigation	YES
5404384	28487710	FM	2	devised and participated in all aspects of the study|performed the ethylene experiments and collected samples for rna isolation and histological studies|performed the qpcr analysis|participated in writing the article	performed the qpcr analysis	Performed the experiments	Investigation	YES
5404384	28487710	FM	2	devised and participated in all aspects of the study|performed the ethylene experiments and collected samples for rna isolation and histological studies|performed the qpcr analysis|participated in writing the article	participated in writing the article	Wrote the paper	Writing - Original Draft	YES
5404384	28487710	JV	2	prepared samples for histological analysis and performed microscopic analyses|participated in writing the article	prepared samples for histological analysis and performed microscopic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5404384	28487710	JV	2	prepared samples for histological analysis and performed microscopic analyses|participated in writing the article	participated in writing the article	Wrote the paper	Writing - Original Draft	YES
5404384	28487710	KF	2	performed the qpcr analysis	performed the qpcr analysis	Performed the experiments	Investigation	YES
5404384	28487710	MC	2	prepared samples for histological analysis and performed microscopic analyses	prepared samples for histological analysis and performed microscopic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5404384	28487710	MP	2	performed the ethylene experiments and collected samples for rna isolation and histological studies|performed the qpcr analysis	performed the ethylene experiments and collected samples for rna isolation and histological studies	Performed the experiments	Investigation	YES
5404384	28487710	MP	2	performed the ethylene experiments and collected samples for rna isolation and histological studies|performed the qpcr analysis	performed the qpcr analysis	Performed the experiments	Investigation	YES
5404384	28487710	NAC	2	domain cdnas	domain cdnas	Performed the experiments	Investigation	YES
5404384	28487710	PR	2	performed the ethylene experiments and collected samples for rna isolation and histological studies|extracted total rna, isolated polygalacturonase cdnas, performed cloning, designed gene specific primers, and performed preliminary rt-pcr expression studies|prepared samples for histological analysis and performed microscopic analyses	performed the ethylene experiments and collected samples for rna isolation and histological studies	Performed the experiments	Investigation	YES
5404384	28487710	PR	2	performed the ethylene experiments and collected samples for rna isolation and histological studies|extracted total rna, isolated polygalacturonase cdnas, performed cloning, designed gene specific primers, and performed preliminary rt-pcr expression studies|prepared samples for histological analysis and performed microscopic analyses	extracted total rna, isolated polygalacturonase cdnas, performed cloning, designed gene specific primers, and performed preliminary rt-pcr expression studies	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5404384	28487710	PR	2	performed the ethylene experiments and collected samples for rna isolation and histological studies|extracted total rna, isolated polygalacturonase cdnas, performed cloning, designed gene specific primers, and performed preliminary rt-pcr expression studies|prepared samples for histological analysis and performed microscopic analyses	prepared samples for histological analysis and performed microscopic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5404384	28487710	PS	2	performed the ethylene experiments and collected samples for rna isolation and histological studies	performed the ethylene experiments and collected samples for rna isolation and histological studies	Performed the experiments	Investigation	YES
5404384	28487710	SD	2	performed the statistical analysis of the transcriptome data|participated in writing the article	performed the statistical analysis of the transcriptome data	Analyzed the data	Formal analysis	YES
5404384	28487710	SD	2	performed the statistical analysis of the transcriptome data|participated in writing the article	participated in writing the article	Wrote the paper	Writing - Original Draft	YES
5404384	28487710	ST	2	coordinated the logistics for fieldwork experiments	coordinated the logistics for fieldwork experiments	Performed the experiments	Investigation|Project administration	YES
5404384	28487710	TT	2	devised and participated in all aspects of the study|coordinated the logistics for fieldwork experiments|performed the ethylene experiments and collected samples for rna isolation and histological studies|performed the phylogenetic analysis|participated in writing the article	devised and participated in all aspects of the study	Conceived and designed the experiments	Conceptualization	YES
5404384	28487710	TT	2	devised and participated in all aspects of the study|coordinated the logistics for fieldwork experiments|performed the ethylene experiments and collected samples for rna isolation and histological studies|performed the phylogenetic analysis|participated in writing the article	coordinated the logistics for fieldwork experiments	Performed the experiments	Investigation|Project administration	YES
5404384	28487710	TT	2	devised and participated in all aspects of the study|coordinated the logistics for fieldwork experiments|performed the ethylene experiments and collected samples for rna isolation and histological studies|performed the phylogenetic analysis|participated in writing the article	performed the ethylene experiments and collected samples for rna isolation and histological studies	Performed the experiments	Investigation	YES
5404384	28487710	TT	2	devised and participated in all aspects of the study|coordinated the logistics for fieldwork experiments|performed the ethylene experiments and collected samples for rna isolation and histological studies|performed the phylogenetic analysis|participated in writing the article	performed the phylogenetic analysis	Performed the experiments	Investigation	YES
5404384	28487710	TT	2	devised and participated in all aspects of the study|coordinated the logistics for fieldwork experiments|performed the ethylene experiments and collected samples for rna isolation and histological studies|performed the phylogenetic analysis|participated in writing the article	participated in writing the article	Wrote the paper	Writing - Original Draft	YES
4966792	27473048	JK	2	they were the main contributors to the paper|provided the computational methods and supervised the work	they were the main contributors to the paper	-	-	NO
4966792	27473048	JK	2	they were the main contributors to the paper|provided the computational methods and supervised the work	provided the computational methods and supervised the work	Performed the experiments	Formal analysis|Supervision	YES
4966792	27473048	MK	2	have contributed the idea to analyze the virus data following the earlier work of jk|also contributed to writing the paper	have contributed the idea to analyze the virus data following the earlier work of jk	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Resources	YES
4966792	27473048	MK	2	have contributed the idea to analyze the virus data following the earlier work of jk|also contributed to writing the paper	also contributed to writing the paper	Wrote the paper	Writing - Original Draft	YES
4966792	27473048	SB	2	have contributed the idea to analyze the virus data following the earlier work of jk|also contributed to writing the paper	have contributed the idea to analyze the virus data following the earlier work of jk	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Resources	YES
4966792	27473048	SB	2	have contributed the idea to analyze the virus data following the earlier work of jk|also contributed to writing the paper	also contributed to writing the paper	Wrote the paper	Writing - Original Draft	YES
4966792	27473048	ZK	2	has performed all computational experiments	has performed all computational experiments	Performed the experiments	Formal analysis|Investigation	YES
4377391	25861618	Anna Kostareva	2	has contributed to conception and design, data collection and analysis, paper writing, and final approval of the paper	has contributed to conception and design, data collection and analysis, paper writing, and final approval of the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Resources|Writing - Original Draft	YES
4377391	25861618	Anna Malashicheva	2	has made conception and design, financial support, paper writing, and final approval of paper	has made conception and design, financial support, paper writing, and final approval of paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Funding acquisition|Writing - Original Draft	YES
4377391	25861618	Anna Zlotina	2	has made data collection and analysis, critical revision, and final approval of the paper	has made data collection and analysis, critical revision, and final approval of the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
4377391	25861618	Dmitry Zverev	2	has done data collection and analysis and final approval of the paper	has done data collection and analysis and final approval of the paper	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4377391	25861618	Tatiana Khodyuchenko	2	has done data collection and analysis, critical revision, and final approval of the paper	has done data collection and analysis, critical revision, and final approval of the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
4377391	25861618	Tatiana Pervunina	2	has contributed to patient recruitment and summarizing clinical information	has contributed to patient recruitment and summarizing clinical information	Performed the experiments	Investigation	YES
4377391	25861618	all authors	2	read and approved the final paper	read and approved the final paper	-	-	NO
5404504	28487709	All authors	2	contributed to the acquisition and interpretation of available literature and the conception of the work	contributed to the acquisition and interpretation of available literature and the conception of the work	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation	YES
5404504	28487709	JC	2	wrote the manuscript, and all authors revised the manuscript and approved this final version	wrote the manuscript, and all authors revised the manuscript and approved this final version	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5404504	28487709	SL	2	wrote the manuscript, and all authors revised the manuscript and approved this final version	wrote the manuscript, and all authors revised the manuscript and approved this final version	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5404504	28487709	XYW	2	wrote the manuscript, and all authors revised the manuscript and approved this final version	wrote the manuscript, and all authors revised the manuscript and approved this final version	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4970254	27485725	EM	2	helped in sampling and data collection and drafting the manuscript	helped in sampling and data collection and drafting the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4970254	27485725	FH	2	helped in target prediction analysis	helped in target prediction analysis	Analyzed the data	Formal analysis	YES
4970254	27485725	KW	2	helped in sampling and data collection and drafting the manuscript	helped in sampling and data collection and drafting the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4970254	27485725	NT	2	helped in sampling and data collection and drafting the manuscript	helped in sampling and data collection and drafting the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4970254	27485725	SP	2	discussed and contributed to data interpretation and helped in drafting the manuscript	discussed and contributed to data interpretation and helped in drafting the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4970254	27485725	XL	2	analysed the microarray data and drafted the manuscript	analysed the microarray data and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5404511	28487720	AK	2	conceptualized the manuscript|contributed in critically revising the draft and updating the manuscript for publication	conceptualized the manuscript	Conceived and designed the experiments	Conceptualization	YES
5404511	28487720	AK	2	conceptualized the manuscript|contributed in critically revising the draft and updating the manuscript for publication	contributed in critically revising the draft and updating the manuscript for publication	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5404511	28487720	CL	2	wrote the manuscript|edited the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5404511	28487720	CL	2	wrote the manuscript|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5404511	28487720	JK	2	edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5404511	28487720	NM	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5404511	28487720	SA	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5404511	28487720	SMG	2	wrote the manuscript|contributed in critically revising the draft and updating the manuscript for publication	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5404511	28487720	SMG	2	wrote the manuscript|contributed in critically revising the draft and updating the manuscript for publication	contributed in critically revising the draft and updating the manuscript for publication	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5404511	28487720	SP	2	edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
4971617	27485510	AMA	PLoS52	devised the overall project	devised the overall project	Conceived and designed the experiments	Conceptualization	YES
4971617	27485510	GB	PLoS52	analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
4971617	27485510	NAMC	PLoS52	devised the overall project|performed fieldwork and isolated p	devised the overall project	Conceived and designed the experiments	Conceptualization	YES
4971617	27485510	NAMC	PLoS52	devised the overall project|performed fieldwork and isolated p	performed fieldwork and isolated p	Performed the experiments	Investigation	YES
4971617	27485510	PSB	PLoS52	devised the overall project	devised the overall project	Conceived and designed the experiments	Conceptualization	YES
5456273	28933396	All authors	2	analyzed and interpreted the results|edited the manuscript and approved the final version to be published	analyzed and interpreted the results	Analyzed the data	Formal analysis	YES
5456273	28933396	All authors	2	analyzed and interpreted the results|edited the manuscript and approved the final version to be published	edited the manuscript and approved the final version to be published	Wrote the paper	Writing - Review & Editing	YES
5456273	28933396	D.P.L.-B.	2	designed and implemented the indices|prepared the manuscript	designed and implemented the indices	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5456273	28933396	D.P.L.-B.	2	designed and implemented the indices|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5456273	28933396	M.E.P.-A.	2	designed and implemented the indices	designed and implemented the indices	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5456273	28933396	M.E.P.-Y.	2	designed and implemented the indices|designed and implemented the indices	designed and implemented the indices	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5456273	28933396	M.E.P.-Y.	2	designed and implemented the indices|designed and implemented the indices	designed and implemented the indices	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5456273	28933396	S.A.-S.	2	prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5404609	28487718	FB	2	contributed equally to the discussion of the topic	contributed equally to the discussion of the topic	-	-	NO
5404609	28487718	MP	2	contributed equally to the discussion of the topic	contributed equally to the discussion of the topic	-	-	NO
4971678	27485828	ATRV	PLoS52	contributed reagents/materials/analysis tools	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4971678	27485828	EOO	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4971678	27485828	FJO	PLoS52	conceived and designed the experiments|contributed reagents/materials/analysis tools	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4971678	27485828	FJO	PLoS52	conceived and designed the experiments|contributed reagents/materials/analysis tools	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4971678	27485828	FMM	PLoS52	contributed reagents/materials/analysis tools	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4971678	27485828	MH	PLoS52	conceived and designed the experiments|contributed reagents/materials/analysis tools	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4971678	27485828	MH	PLoS52	conceived and designed the experiments|contributed reagents/materials/analysis tools	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4971678	27485828	MM	PLoS52	conceived and designed the experiments|contributed reagents/materials/analysis tools	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4971678	27485828	MM	PLoS52	conceived and designed the experiments|contributed reagents/materials/analysis tools	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5456275	28933398	Both authors	2	made substantive intellectual contributions to the presented study|have made substantial contributions to the conception and design and to the acquisition and interpretation of data, have been involved in drafting the manuscript and revising it critically for important intellectual content, and have given final approval of the version to be published	made substantive intellectual contributions to the presented study	-	-	NO
5456275	28933398	Both authors	2	made substantive intellectual contributions to the presented study|have made substantial contributions to the conception and design and to the acquisition and interpretation of data, have been involved in drafting the manuscript and revising it critically for important intellectual content, and have given final approval of the version to be published	have made substantial contributions to the conception and design and to the acquisition and interpretation of data, have been involved in drafting the manuscript and revising it critically for important intellectual content, and have given final approval of the version to be published	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5456276	28933397	All authors	2	edited the manuscript and approved the final version to be published	edited the manuscript and approved the final version to be published	Wrote the paper	Writing - Review & Editing	YES
5456276	28933397	Lourdes de Souza	2	contributed equally in performing content analysis and coding	contributed equally in performing content analysis and coding	Performed the experiments	Investigation	YES
5456276	28933397	Najma Naz	2	conducted the interviews and transcribed it|prepared the manuscript	conducted the interviews and transcribed it	Performed the experiments	Investigation	YES
5456276	28933397	Najma Naz	2	conducted the interviews and transcribed it|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5456276	28933397	Sabiha Khanum	2	conducted the interviews and transcribed it|prepared the manuscript	conducted the interviews and transcribed it	Performed the experiments	Investigation	YES
5456276	28933397	Sabiha Khanum	2	conducted the interviews and transcribed it|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
4971691	27485608	BW	PLoS52	designed the research|performed research|analyzed data|wrote the paper	designed the research	Conceived and designed the experiments	Methodology	YES
4971691	27485608	BW	PLoS52	designed the research|performed research|analyzed data|wrote the paper	performed research	Performed the experiments	Investigation	YES
4971691	27485608	BW	PLoS52	designed the research|performed research|analyzed data|wrote the paper	analyzed data	Analyzed the data	Formal analysis	YES
4971691	27485608	BW	PLoS52	designed the research|performed research|analyzed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4971691	27485608	GY	PLoS52	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
4971691	27485608	HL	PLoS52	designed the research|performed research|analyzed data|wrote the paper	designed the research	Conceived and designed the experiments	Methodology	YES
4971691	27485608	HL	PLoS52	designed the research|performed research|analyzed data|wrote the paper	performed research	Performed the experiments	Investigation	YES
4971691	27485608	HL	PLoS52	designed the research|performed research|analyzed data|wrote the paper	analyzed data	Analyzed the data	Formal analysis	YES
4971691	27485608	HL	PLoS52	designed the research|performed research|analyzed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4971691	27485608	JZ	PLoS52	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
4971691	27485608	QX	PLoS52	performed research|analyzed data	performed research	Performed the experiments	Investigation	YES
4971691	27485608	QX	PLoS52	performed research|analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
4971691	27485608	XL	PLoS52	designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
4971691	27485608	YH	PLoS52	designed the research|analyzed data	designed the research	Conceived and designed the experiments	Methodology	YES
4971691	27485608	YH	PLoS52	designed the research|analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
4971691	27485608	YL	PLoS52	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
4971691	27485608	YW	PLoS52	performed research|analyzed data	performed research	Performed the experiments	Investigation	YES
4971691	27485608	YW	PLoS52	performed research|analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5456277	28933401	J.N.L.	2	provided supervision and assistance with manuscript revision	provided supervision and assistance with manuscript revision	Wrote the paper	Supervision|Writing - Review & Editing	YES
5456277	28933401	J.R.K.	2	performed the literature review	performed the literature review	Performed the experiments	Formal analysis|Investigation	YES
5456277	28933401	L.L.W.	2	provided supervision and assistance with manuscript revision	provided supervision and assistance with manuscript revision	Wrote the paper	Supervision|Writing - Review & Editing	YES
5456277	28933401	R.R.B.	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4971723	27488257	BM	PLoS52	designed and performed the genome assemblies	designed and performed the genome assemblies	Conceived and designed the experiments|Performed the experiments	Investigation	YES
4971723	27488257	DKG	PLoS52	designed and performed the genome assemblies	designed and performed the genome assemblies	Conceived and designed the experiments|Performed the experiments	Investigation	YES
4971723	27488257	HBB	PLoS52	conceived of the study|helped to design the experiment|drafted the manuscript|provided computational infrastructure	conceived of the study	Conceived and designed the experiments	Conceptualization	YES
4971723	27488257	HBB	PLoS52	conceived of the study|helped to design the experiment|drafted the manuscript|provided computational infrastructure	helped to design the experiment	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4971723	27488257	HBB	PLoS52	conceived of the study|helped to design the experiment|drafted the manuscript|provided computational infrastructure	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4971723	27488257	HBB	PLoS52	conceived of the study|helped to design the experiment|drafted the manuscript|provided computational infrastructure	provided computational infrastructure	-	Formal analysis	YES
4971723	27488257	MT	PLoS52	designed and performed the genome assemblies|provided computational infrastructure	designed and performed the genome assemblies	Conceived and designed the experiments|Performed the experiments	Investigation	YES
4971723	27488257	MT	PLoS52	designed and performed the genome assemblies|provided computational infrastructure	provided computational infrastructure	-	Formal analysis	YES
4971723	27488257	NJT	PLoS52	extracted the dna|participated in genome annotation|analysed the data|conceived of the study|helped to design the experiment|drafted the manuscript	extracted the dna	Performed the experiments	Investigation	YES
4971723	27488257	NJT	PLoS52	extracted the dna|participated in genome annotation|analysed the data|conceived of the study|helped to design the experiment|drafted the manuscript	participated in genome annotation	Analyzed the data	Data curation|Formal analysis	YES
4971723	27488257	NJT	PLoS52	extracted the dna|participated in genome annotation|analysed the data|conceived of the study|helped to design the experiment|drafted the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
4971723	27488257	NJT	PLoS52	extracted the dna|participated in genome annotation|analysed the data|conceived of the study|helped to design the experiment|drafted the manuscript	conceived of the study	Conceived and designed the experiments	Conceptualization	YES
4971723	27488257	NJT	PLoS52	extracted the dna|participated in genome annotation|analysed the data|conceived of the study|helped to design the experiment|drafted the manuscript	helped to design the experiment	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4971723	27488257	NJT	PLoS52	extracted the dna|participated in genome annotation|analysed the data|conceived of the study|helped to design the experiment|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4971723	27488257	RS	PLoS52	designed and performed the genome assemblies	designed and performed the genome assemblies	Conceived and designed the experiments|Performed the experiments	Investigation	YES
4971723	27488257	TS	PLoS52	participated in genome annotation|helped to design the experiment|provided computational infrastructure	participated in genome annotation	Analyzed the data	Data curation|Formal analysis	YES
4971723	27488257	TS	PLoS52	participated in genome annotation|helped to design the experiment|provided computational infrastructure	helped to design the experiment	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4971723	27488257	TS	PLoS52	participated in genome annotation|helped to design the experiment|provided computational infrastructure	provided computational infrastructure	-	Formal analysis	YES
5404645	28487705	DM	PLoS5	Performed the genotyping experiments	Performed the genotyping experiments	Performed the experiments	Investigation	YES
5404645	28487705	DN	PLoS5	Performed the phenotyping experiments|Performed the genotyping experiments	Performed the phenotyping experiments	Performed the experiments	Investigation	YES
5404645	28487705	DN	PLoS5	Performed the phenotyping experiments|Performed the genotyping experiments	Performed the genotyping experiments	Performed the experiments	Investigation	YES
5404645	28487705	EP	PLoS5	Conceived and designed the experiments|Performed the genotyping experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5404645	28487705	EP	PLoS5	Conceived and designed the experiments|Performed the genotyping experiments|Analyzed the data|Wrote the paper	Performed the genotyping experiments	Performed the experiments	Investigation	YES
5404645	28487705	EP	PLoS5	Conceived and designed the experiments|Performed the genotyping experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5404645	28487705	EP	PLoS5	Conceived and designed the experiments|Performed the genotyping experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5404645	28487705	SB	PLoS5	Performed the genotyping experiments	Performed the genotyping experiments	Performed the experiments	Investigation	YES
5404645	28487705	SD	PLoS5	Performed the phenotyping experiments|Performed the genotyping experiments	Performed the phenotyping experiments	Performed the experiments	Investigation	YES
5404645	28487705	SD	PLoS5	Performed the phenotyping experiments|Performed the genotyping experiments	Performed the genotyping experiments	Performed the experiments	Investigation	YES
5404645	28487705	SM	PLoS5	Performed the phenotyping experiments	Performed the phenotyping experiments	Performed the experiments	Investigation	YES
5404645	28487705	SP	PLoS5	Conceived and designed the experiments|Performed the phenotyping experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5404645	28487705	SP	PLoS5	Conceived and designed the experiments|Performed the phenotyping experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the phenotyping experiments	Performed the experiments	Investigation	YES
5404645	28487705	SP	PLoS5	Conceived and designed the experiments|Performed the phenotyping experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5404645	28487705	SP	PLoS5	Conceived and designed the experiments|Performed the phenotyping experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5404645	28487705	ST	PLoS5	Performed the genotyping experiments	Performed the genotyping experiments	Performed the experiments	Investigation	YES
4971756	27485430	JM	2	designed the study, carried out the experiments and data analysis, drafted and finalized the manuscript	designed the study, carried out the experiments and data analysis, drafted and finalized the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
4971756	27485430	OD	2	designed the study, carried out the experiments and data analysis, drafted and finalized the manuscript	designed the study, carried out the experiments and data analysis, drafted and finalized the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
4971756	27485430	SP	2	performed data collection and sample preparation for bead chip analysis	performed data collection and sample preparation for bead chip analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5456278	28933402	J.J.	4	authored the majority of the manuscript with critical review and additions by	authored the majority of the manuscript with critical review and additions by	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5405063	28491073	All authors	2	listed made substantial intellectual contribution to the work, wrote the manuscript together and approved it for publication	listed made substantial intellectual contribution to the work, wrote the manuscript together and approved it for publication	Wrote the paper	Writing - Original Draft	YES
4972977	27487841	EJ	2	designed and performed the experiments	designed and performed the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4972977	27487841	JB	2	designed the experiments, participated in interpretation of the results and preparing the manuscript	designed the experiments, participated in interpretation of the results and preparing the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4972977	27487841	JR	2	performed genome assembly	performed genome assembly	Performed the experiments	Investigation	YES
4972977	27487841	LP	2	performed genome assembly and helped to prepare the manuscript	performed genome assembly and helped to prepare the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4972977	27487841	MA	2	performed genome annotation, carried out rna seq data analysis	performed genome annotation, carried out rna seq data analysis	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
4972977	27487841	PA	2	designed the experiments, participated in interpretation of the results and preparing the manuscript	designed the experiments, participated in interpretation of the results and preparing the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4972977	27487841	PJ	2	designed and performed the experiments, participated in the genome annotation, interpretation of the results and preparing the manuscript	designed and performed the experiments, participated in the genome annotation, interpretation of the results and preparing the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4972977	27487841	TFBS	2	search and interpretation of the results, wrote the manuscript	search and interpretation of the results, wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4972977	27487841	TR	2	performed genome assembly	performed genome assembly	Performed the experiments	Investigation	YES
5456279	28933400	A.A.M.	2	involved in the study design, data analysis, and discussion	involved in the study design, data analysis, and discussion	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5456279	28933400	A.M.S.A.	2	contributed for data collection, and data analysis	contributed for data collection, and data analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5456279	28933400	All authors	2	contributed equally to the study	contributed equally to the study	-	-	NO
5456279	28933400	M.S.	2	involved in the study analysis and literature review	involved in the study analysis and literature review	-	Formal analysis	YES
5405077	28491075	DH	7	identified the resistant parental line, made the cross and participated in the field experiments|conceived and directed the project and revised the manuscript	identified the resistant parental line, made the cross and participated in the field experiments	Performed the experiments	Investigation	YES
5405077	28491075	DH	7	identified the resistant parental line, made the cross and participated in the field experiments|conceived and directed the project and revised the manuscript	conceived and directed the project and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Supervision|Writing - Review & Editing	YES
5405077	28491075	JM	7	participated in field experiments and contributed to the genotyping experiment	participated in field experiments and contributed to the genotyping experiment	Performed the experiments	Investigation	YES
5405077	28491075	JW	7	conducted the experiments, analyzed the data, and wrote the manuscript	conducted the experiments, analyzed the data, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5405077	28491075	LH	7	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5405077	28491075	QW	7	identified the resistant parental line, made the cross and participated in the field experiments|assisted in analyzing the data	identified the resistant parental line, made the cross and participated in the field experiments	Performed the experiments	Investigation	YES
5405077	28491075	QW	7	identified the resistant parental line, made the cross and participated in the field experiments|assisted in analyzing the data	assisted in analyzing the data	Analyzed the data	Formal analysis	YES
5405077	28491075	QZ	7	assisted in analyzing the data	assisted in analyzing the data	Analyzed the data	Formal analysis	YES
5405077	28491075	SH	7	participated in field experiments and contributed to the genotyping experiment	participated in field experiments and contributed to the genotyping experiment	Performed the experiments	Investigation	YES
5405077	28491075	SL	7	participated in field experiments and contributed to the genotyping experiment	participated in field experiments and contributed to the genotyping experiment	Performed the experiments	Investigation	YES
5405077	28491075	ZK	7	conceived and directed the project and revised the manuscript	conceived and directed the project and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Supervision|Writing - Review & Editing	YES
4973035	27488048	GW	2	compared the ethylene and water-deficit stress treatment expression profiles	compared the ethylene and water-deficit stress treatment expression profiles	Performed the experiments	Investigation	YES
4973035	27488048	MP	2	helped draft the manuscript and supervised the study	helped draft the manuscript and supervised the study	Wrote the paper	Supervision|Writing - Original Draft	YES
4973035	27488048	WBL	2	participated in the study design, performed the microarray analysis and drafted the manuscript	participated in the study design, performed the microarray analysis and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
4973035	27488048	YLY	2	prepared the cassava material and detected the phenotypes	prepared the cassava material and detected the phenotypes	Performed the experiments	Investigation	YES
4973035	27488048	YYL	2	prepared the cassava material and detected the phenotypes	prepared the cassava material and detected the phenotypes	Performed the experiments	Investigation	YES
5456283	28933407	C.M.J.	2	helped write the manuscript	helped write the manuscript	Wrote the paper	Writing - Original Draft	YES
4973071	27487946	BM	2	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
4973071	27487946	GD	2	provided new reagents or analytical tools	provided new reagents or analytical tools	Contributed reagents/materials/analysis tools	Resources	YES
4973071	27487946	HC	2	contributed uplc analysis	contributed uplc analysis	-	-	NO
4973071	27487946	HL	2	conceived and designed research|conducted experiments|analyzed data	conceived and designed research	Conceived and designed the experiments	Conceptualization|Methodology	YES
4973071	27487946	HL	2	conceived and designed research|conducted experiments|analyzed data	conducted experiments	Performed the experiments	Investigation	YES
4973071	27487946	HL	2	conceived and designed research|conducted experiments|analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
4973071	27487946	JL	2	provided guidance for experimental design	provided guidance for experimental design	Conceived and designed the experiments	Methodology|Supervision	YES
4973071	27487946	NH	2	conceived and designed research|analyzed data|revised the manuscript	conceived and designed research	Conceived and designed the experiments	Conceptualization|Methodology	YES
4973071	27487946	NH	2	conceived and designed research|analyzed data|revised the manuscript	analyzed data	Analyzed the data	Formal analysis	YES
4973071	27487946	NH	2	conceived and designed research|analyzed data|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5405116	28491072	LW	2	carried out all the experiments and data analysis|conceived the project, designed the experiments and drafted the manuscript	carried out all the experiments and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5405116	28491072	LW	2	carried out all the experiments and data analysis|conceived the project, designed the experiments and drafted the manuscript	conceived the project, designed the experiments and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
5405116	28491072	ML	2	supervised the analysis and critically revised the manuscript	supervised the analysis and critically revised the manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
5405116	28491072	YW	2	conceived the project, designed the experiments and drafted the manuscript|supervised the analysis and critically revised the manuscript	conceived the project, designed the experiments and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
5405116	28491072	YW	2	conceived the project, designed the experiments and drafted the manuscript|supervised the analysis and critically revised the manuscript	supervised the analysis and critically revised the manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
5405116	28491072	ZL	2	carried out all the experiments and data analysis|conceived the project, designed the experiments and drafted the manuscript	carried out all the experiments and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5405116	28491072	ZL	2	carried out all the experiments and data analysis|conceived the project, designed the experiments and drafted the manuscript	conceived the project, designed the experiments and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
4378326	25861644	Jianxin Guo	2	contributed equally to this work	contributed equally to this work	-	-	NO
4378326	25861644	Qiang Liu	2	contributed equally to this work	contributed equally to this work	-	-	NO
4973090	27488180	HS	2	supervised the study, contributed to study design, and wrote the manuscript	supervised the study, contributed to study design, and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Original Draft	YES
4973090	27488180	PR	2	contributed to study design and wrote the manuscript	contributed to study design and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4973090	27488180	WY	2	had the initial idea to the approach, designed the study, performed analyses and wrote the manuscript	had the initial idea to the approach, designed the study, performed analyses and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4973544	27491876	AL	2	designed, performed and analyzed experiments|wrote the manuscript	designed, performed and analyzed experiments	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
4973544	27491876	AL	2	designed, performed and analyzed experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4973544	27491876	ES	2	designed, performed and analyzed experiments|wrote the manuscript	designed, performed and analyzed experiments	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
4973544	27491876	ES	2	designed, performed and analyzed experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4973544	27491876	PD	2	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5405118	28491074	JS	2	then jointly edited the final version	then jointly edited the final version	Wrote the paper	Writing - Review & Editing	YES
5405118	28491074	SS	2	then jointly edited the final version	then jointly edited the final version	Wrote the paper	Writing - Review & Editing	YES
5456285	28933406	Ding Xiang Liu	PLoS52	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5456285	28933406	James P. Tam	PLoS52	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5456285	28933406	Yan Ling Ng	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5456285	28933406	Yvonne Xinyi Lim	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4973553	27491780	AH	2	designed the research|performed the research|analyzed data|wrote the manuscript in consultation with all authors	designed the research	Conceived and designed the experiments	Methodology	YES
4973553	27491780	AH	2	designed the research|performed the research|analyzed data|wrote the manuscript in consultation with all authors	performed the research	Performed the experiments	Investigation	YES
4973553	27491780	AH	2	designed the research|performed the research|analyzed data|wrote the manuscript in consultation with all authors	analyzed data	Analyzed the data	Formal analysis	YES
4973553	27491780	AH	2	designed the research|performed the research|analyzed data|wrote the manuscript in consultation with all authors	wrote the manuscript in consultation with all authors	Wrote the paper	Writing - Original Draft	YES
4973553	27491780	AK	2	designed the research|analyzed data|wrote the manuscript in consultation with all authors	designed the research	Conceived and designed the experiments	Methodology	YES
4973553	27491780	AK	2	designed the research|analyzed data|wrote the manuscript in consultation with all authors	analyzed data	Analyzed the data	Formal analysis	YES
4973553	27491780	AK	2	designed the research|analyzed data|wrote the manuscript in consultation with all authors	wrote the manuscript in consultation with all authors	Wrote the paper	Writing - Original Draft	YES
4973553	27491780	CV	2	performed the research	performed the research	Performed the experiments	Investigation	YES
4973553	27491780	DB	2	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
4973553	27491780	EJ	2	performed the research	performed the research	Performed the experiments	Investigation	YES
4973553	27491780	JZ	2	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
4973553	27491780	LP	2	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
4973553	27491780	ZW	2	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
4378597	25861653	Jie Wang	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
4378597	25861653	Xuemei Lu	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
5405123	28491078	FF	2	organized the manuscript and wrote the arabidopsis and rice sections|revised the manuscript	organized the manuscript and wrote the arabidopsis and rice sections	Wrote the paper	Writing - Original Draft	YES
5405123	28491078	FF	2	organized the manuscript and wrote the arabidopsis and rice sections|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5405123	28491078	JG-A	2	wrote the temperate cereals section	wrote the temperate cereals section	Wrote the paper	Writing - Original Draft	YES
5405123	28491078	MC	2	wrote the maize and sorghum section and prepared figure	wrote the maize and sorghum section and prepared figure	Wrote the paper	Visualization|Writing - Original Draft	YES
5405123	28491078	VB	2	organized the manuscript and wrote the arabidopsis and rice sections	organized the manuscript and wrote the arabidopsis and rice sections	Wrote the paper	Writing - Original Draft	YES
4974685	27495902	All authors	2	gave final approval and agree to be accountable for all aspects of the work, ensuring its integrity and accuracy	gave final approval and agree to be accountable for all aspects of the work, ensuring its integrity and accuracy	-	-	NO
4974685	27495902	BL	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4974685	27495902	CZ	2	contributed to the study design|drafted the manuscript	contributed to the study design	Conceived and designed the experiments	Methodology	YES
4974685	27495902	CZ	2	contributed to the study design|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4974685	27495902	JL	2	contributed to the conception and design of the study|critically revised the manuscript	contributed to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4974685	27495902	JL	2	contributed to the conception and design of the study|critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4974685	27495902	LB	2	contributed to sample acquisition	contributed to sample acquisition	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4974685	27495902	QZ	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4974685	27495902	YF	2	contributed to data analysis and interpretation|drafted the manuscript	contributed to data analysis and interpretation	Analyzed the data	Formal analysis	YES
4974685	27495902	YF	2	contributed to data analysis and interpretation|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4974685	27495902	YHGL	2	contributed to sample acquisition|drafted the manuscript	contributed to sample acquisition	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4974685	27495902	YHGL	2	contributed to sample acquisition|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4974685	27495902	YHIL	2	contributed to data acquisition, analysis, and interpretation|drafted the manuscript	contributed to data acquisition, analysis, and interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4974685	27495902	YHIL	2	contributed to data acquisition, analysis, and interpretation|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4974685	27495902	ZQ	2	contributed to sample acquisition	contributed to sample acquisition	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4974685	27495902	ZZ	2	contributed to the conception and design of the study|critically revised the manuscript	contributed to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4974685	27495902	ZZ	2	contributed to the conception and design of the study|critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5456286	28933409	A.G.	PLoS52	contributed materials/analysis tools	contributed materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5456286	28933409	E.H.B.	PLoS52	performed the experiments|contributed materials/analysis tools	performed the experiments	Performed the experiments	Investigation	YES
5456286	28933409	E.H.B.	PLoS52	performed the experiments|contributed materials/analysis tools	contributed materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5456286	28933409	E.S.J.	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5456286	28933409	F.D.P.	PLoS52	conceived and designed the experiments|contributed materials/analysis tools	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5456286	28933409	F.D.P.	PLoS52	conceived and designed the experiments|contributed materials/analysis tools	contributed materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5456286	28933409	M.W.L.	PLoS52	analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5456286	28933409	M.W.L.	PLoS52	analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5456286	28933409	N.Y.F.	PLoS52	organized and coordinated subject admissions	organized and coordinated subject admissions	-	Project administration	YES
5456286	28933409	R.M.	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5456286	28933409	R.W.L.	PLoS52	conceived and designed the experiments|analyzed the data|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5456286	28933409	R.W.L.	PLoS52	conceived and designed the experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5456286	28933409	R.W.L.	PLoS52	conceived and designed the experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5456286	28933409	S.M.	PLoS52	contributed materials/analysis tools	contributed materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5456286	28933409	S.Y.	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5405128	28491076	FB	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5405128	28491076	KW	PLoS52	performed the experiments and analyzed the data|wrote the paper	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5405128	28491076	KW	PLoS52	performed the experiments and analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5405128	28491076	MS	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5405128	28491076	RG	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5405128	28491076	SR	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5405128	28491076	SU	PLoS52	performed the experiments and analyzed the data|wrote the paper	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5405128	28491076	SU	PLoS52	performed the experiments and analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4974748	27496340	All authors	2	read, corrected and approved the final manuscript	read, corrected and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4974748	27496340	BRB	2	collected the rna for sequencing, cloned genes, and performed the phylogenetic analyses	collected the rna for sequencing, cloned genes, and performed the phylogenetic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4974748	27496340	HCC	2	conceived of the study|performed the bioinformatics tasks and drafted the manuscript	conceived of the study	Conceived and designed the experiments	Conceptualization	YES
4974748	27496340	HCC	2	conceived of the study|performed the bioinformatics tasks and drafted the manuscript	performed the bioinformatics tasks and drafted the manuscript	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4974748	27496340	MMP	2	cloned genes, carried out in situ hybridizations in early stages, and helped to write the manuscript	cloned genes, carried out in situ hybridizations in early stages, and helped to write the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4974748	27496340	SQS	2	conceived of the study|designed and coordinated the study, and wrote the manuscript	conceived of the study	Conceived and designed the experiments	Conceptualization	YES
4974748	27496340	SQS	2	conceived of the study|designed and coordinated the study, and wrote the manuscript	designed and coordinated the study, and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft	YES
5405130	28491079	QF	2	designed the study|guided the experiments	designed the study	Conceived and designed the experiments	Methodology	YES
5405130	28491079	QF	2	designed the study|guided the experiments	guided the experiments	-	Supervision	YES
5405130	28491079	RZ	2	designed the study|guided the experiments	designed the study	Conceived and designed the experiments	Methodology	YES
5405130	28491079	RZ	2	designed the study|guided the experiments	guided the experiments	-	Supervision	YES
5405130	28491079	SD	2	guided the experiments	guided the experiments	-	Supervision	YES
5405130	28491079	YL	2	designed the study|guided the experiments	designed the study	Conceived and designed the experiments	Methodology	YES
5405130	28491079	YL	2	designed the study|guided the experiments	guided the experiments	-	Supervision	YES
5405130	28491079	ZN	2	guided the experiments	guided the experiments	-	Supervision	YES
2811100	20017918	APM	1	Study concept and design|Critical revisions for important intellectual content|Supervision of database	Study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
2811100	20017918	APM	1	Study concept and design|Critical revisions for important intellectual content|Supervision of database	Critical revisions for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
2811100	20017918	APM	1	Study concept and design|Critical revisions for important intellectual content|Supervision of database	Supervision of database	Contributed reagents/materials/analysis tools	Software|Supervision	YES
2811100	20017918	AVR	1	Study concept and design|Analysis and interpretation of data	Study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
2811100	20017918	AVR	1	Study concept and design|Analysis and interpretation of data	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
2811100	20017918	DR	1	Acquisition of data|Critical revisions for important intellectual content|Administrative, technical or material support	Acquisition of data	Performed the experiments	Investigation	YES
2811100	20017918	DR	1	Acquisition of data|Critical revisions for important intellectual content|Administrative, technical or material support	Critical revisions for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
2811100	20017918	DR	1	Acquisition of data|Critical revisions for important intellectual content|Administrative, technical or material support	Administrative, technical or material support	Performed the experiments	Investigation|Project administration	YES
2811100	20017918	DW	1	Study concept and design|Analysis and interpretation of data|Critical revisions for important intellectual content	Study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
2811100	20017918	DW	1	Study concept and design|Analysis and interpretation of data|Critical revisions for important intellectual content	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
2811100	20017918	DW	1	Study concept and design|Analysis and interpretation of data|Critical revisions for important intellectual content	Critical revisions for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
2811100	20017918	IMS	1	Study concept and design|Acquisition of data|Critical revisions for important intellectual content|Obtaining funding	Study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
2811100	20017918	IMS	1	Study concept and design|Acquisition of data|Critical revisions for important intellectual content|Obtaining funding	Acquisition of data	Performed the experiments	Investigation	YES
2811100	20017918	IMS	1	Study concept and design|Acquisition of data|Critical revisions for important intellectual content|Obtaining funding	Critical revisions for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
2811100	20017918	IMS	1	Study concept and design|Acquisition of data|Critical revisions for important intellectual content|Obtaining funding	Obtaining funding	-	Funding acquisition	YES
2811100	20017918	PM	1	Acquisition of data|Critical revisions for important intellectual content|Administrative, technical or material support	Acquisition of data	Performed the experiments	Investigation	YES
2811100	20017918	PM	1	Acquisition of data|Critical revisions for important intellectual content|Administrative, technical or material support	Critical revisions for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
2811100	20017918	PM	1	Acquisition of data|Critical revisions for important intellectual content|Administrative, technical or material support	Administrative, technical or material support	Performed the experiments	Investigation|Project administration	YES
4380099	25853142	Job Harenberg	4	or analysis and interpretation of data were performed by|Drafting the paper or revising it critically for important intellectual content was done by|Final approval of the version to be published was done by	or analysis and interpretation of data were performed by	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4380099	25853142	Job Harenberg	4	or analysis and interpretation of data were performed by|Drafting the paper or revising it critically for important intellectual content was done by|Final approval of the version to be published was done by	Drafting the paper or revising it critically for important intellectual content was done by	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4380099	25853142	Job Harenberg	4	or analysis and interpretation of data were performed by|Drafting the paper or revising it critically for important intellectual content was done by|Final approval of the version to be published was done by	Final approval of the version to be published was done by	-	-	NO
4380099	25853142	Konrad Obermann	4	Drafting the paper or revising it critically for important intellectual content was done by|Final approval of the version to be published was done by	Drafting the paper or revising it critically for important intellectual content was done by	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4380099	25853142	Konrad Obermann	4	Drafting the paper or revising it critically for important intellectual content was done by|Final approval of the version to be published was done by	Final approval of the version to be published was done by	-	-	NO
4380099	25853142	Martin Krejczy	4	or analysis and interpretation of data were performed by|Drafting the paper or revising it critically for important intellectual content was done by|Final approval of the version to be published was done by	or analysis and interpretation of data were performed by	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4380099	25853142	Martin Krejczy	4	or analysis and interpretation of data were performed by|Drafting the paper or revising it critically for important intellectual content was done by|Final approval of the version to be published was done by	Drafting the paper or revising it critically for important intellectual content was done by	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4380099	25853142	Martin Krejczy	4	or analysis and interpretation of data were performed by|Drafting the paper or revising it critically for important intellectual content was done by|Final approval of the version to be published was done by	Final approval of the version to be published was done by	-	-	NO
4380099	25853142	Martin Wehling	4	Drafting the paper or revising it critically for important intellectual content was done by|Final approval of the version to be published was done by	Drafting the paper or revising it critically for important intellectual content was done by	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4380099	25853142	Martin Wehling	4	Drafting the paper or revising it critically for important intellectual content was done by|Final approval of the version to be published was done by	Final approval of the version to be published was done by	-	-	NO
4974753	27495254	HZ	2	performed the data analysis and wrote the manuscript	performed the data analysis and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4974753	27495254	KD	2	performed the comparative fish experiment	performed the comparative fish experiment	Performed the experiments	Investigation	YES
4974753	27495254	LG	2	participated in ssr fingerprinting and genetic diversity analysis	participated in ssr fingerprinting and genetic diversity analysis	Performed the experiments	Investigation	YES
4974753	27495254	LY	2	conceived the study, designed the experiments, wrote and revised the manuscript	conceived the study, designed the experiments, wrote and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
4974753	27495254	PS	2	conducted validation of ssr polymorphism, genetic diversity and population structure analysis	conducted validation of ssr polymorphism, genetic diversity and population structure analysis	Performed the experiments	Investigation|Validation	YES
4974753	27495254	SS	2	participated in ssr fingerprinting and genetic diversity analysis	participated in ssr fingerprinting and genetic diversity analysis	Performed the experiments	Investigation	YES
4974753	27495254	YL	2	participated in ssr fingerprinting and genetic diversity analysis	participated in ssr fingerprinting and genetic diversity analysis	Performed the experiments	Investigation	YES
4974753	27495254	YW	2	conceived the study, designed the experiments, wrote and revised the manuscript	conceived the study, designed the experiments, wrote and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5405133	28491066	JW	2	discussed the data and wrote the manuscript	discussed the data and wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5405133	28491066	JZ	2	performed the research and analyzed the data|discussed the data and wrote the manuscript	performed the research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5405133	28491066	JZ	2	performed the research and analyzed the data|discussed the data and wrote the manuscript	discussed the data and wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5405133	28491066	LL	2	designed the study|discussed the data and wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5405133	28491066	LL	2	designed the study|discussed the data and wrote the manuscript	discussed the data and wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5405133	28491066	SH	2	performed the research and analyzed the data|discussed the data and wrote the manuscript	performed the research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5405133	28491066	SH	2	performed the research and analyzed the data|discussed the data and wrote the manuscript	discussed the data and wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5405133	28491066	SI	2	discussed the data and wrote the manuscript	discussed the data and wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5405133	28491066	VD	2	performed the research and analyzed the data|discussed the data and wrote the manuscript	performed the research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5405133	28491066	VD	2	performed the research and analyzed the data|discussed the data and wrote the manuscript	discussed the data and wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5405133	28491066	ZC	2	discussed the data and wrote the manuscript	discussed the data and wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5456287	28933404	SD	2	wrote the other parts and reviewed the paper	wrote the other parts and reviewed the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
2822750	20205768	All authors	2	contributed to writing of the report and have seen and approved the final version of the report	contributed to writing of the report and have seen and approved the final version of the report	Wrote the paper	-	YES
2823611	20205784	JVL	2	addressed the reviewers comments	addressed the reviewers comments	-	-	NO
2823611	20205784	MW	2	reviewed and added additional material|addressed the reviewers comments	reviewed and added additional material	-	-	NO
2823611	20205784	MW	2	reviewed and added additional material|addressed the reviewers comments	addressed the reviewers comments	-	-	NO
2823611	20205784	NC	2	fact checked the changes	fact checked the changes	-	-	NO
2823611	20205784	SM	2	fully reviewed and edited the next draft	fully reviewed and edited the next draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4974774	27496087	AZ	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4974774	27496087	DBA	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4974774	27496087	EH	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4974774	27496087	GLF	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4974774	27496087	GV	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4974774	27496087	MRT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4974774	27496087	MRT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4974774	27496087	MRT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4974774	27496087	MRT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4974774	27496087	RB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4974774	27496087	RB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4974774	27496087	RB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4974774	27496087	RB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4974774	27496087	RH	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4974774	27496087	SAS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4974774	27496087	SAS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4974774	27496087	SAS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4974774	27496087	SS	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4974774	27496087	SSP	PLoS5	Conceived and designed the experiments|Wrote the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4974774	27496087	SSP	PLoS5	Conceived and designed the experiments|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
2827379	20205896	AMG	2	performed the serotyping and env sequencing	performed the serotyping and env sequencing	Performed the experiments	Investigation	YES
2827379	20205896	AMR	2	contributed clinical data	contributed clinical data	Contributed reagents/materials/analysis tools	Resources	YES
2827379	20205896	IC	2	performed the serotyping and env sequencing	performed the serotyping and env sequencing	Performed the experiments	Investigation	YES
2827379	20205896	IT	2	contributed to the preparation of the manuscript|performed the serotyping and env sequencing	contributed to the preparation of the manuscript	Wrote the paper	Writing - Original Draft	YES
2827379	20205896	IT	2	contributed to the preparation of the manuscript|performed the serotyping and env sequencing	performed the serotyping and env sequencing	Performed the experiments	Investigation	YES
2827379	20205896	JM	2	performed the serotyping and env sequencing	performed the serotyping and env sequencing	Performed the experiments	Investigation	YES
2827379	20205896	MS	2	contributed to the preparation of the manuscript|performed the serotyping and env sequencing	contributed to the preparation of the manuscript	Wrote the paper	Writing - Original Draft	YES
2827379	20205896	MS	2	contributed to the preparation of the manuscript|performed the serotyping and env sequencing	performed the serotyping and env sequencing	Performed the experiments	Investigation	YES
2827379	20205896	MZ	2	performed the serotyping and env sequencing	performed the serotyping and env sequencing	Performed the experiments	Investigation	YES
2827379	20205896	NO	2	performed the serotyping and env sequencing	performed the serotyping and env sequencing	Performed the experiments	Investigation	YES
2827379	20205896	PE	2	coordinated the data collection and wrote the manuscript	coordinated the data collection and wrote the manuscript	Performed the experiments|Wrote the paper	Investigation|Project administration|Writing - Original Draft	YES
2827379	20205896	SOS	2	performed the serotyping and env sequencing	performed the serotyping and env sequencing	Performed the experiments	Investigation	YES
5405135	28491067	All authors	2	reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5405135	28491067	BY	2	provided advice on the experimental design	provided advice on the experimental design	Conceived and designed the experiments	Methodology	YES
5405135	28491067	CM	2	provided advice on the experimental design	provided advice on the experimental design	Conceived and designed the experiments	Methodology	YES
5405135	28491067	HW	2	performed phenotype measurements|analyzed all data|wrote the manuscript	performed phenotype measurements	Performed the experiments	Investigation	YES
5405135	28491067	HW	2	performed phenotype measurements|analyzed all data|wrote the manuscript	analyzed all data	Analyzed the data	Formal analysis	YES
5405135	28491067	HW	2	performed phenotype measurements|analyzed all data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5405135	28491067	JG	2	performed phenotype measurements	performed phenotype measurements	Performed the experiments	Investigation	YES
5405135	28491067	JS	2	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5405135	28491067	JT	2	provided advice on the experimental design	provided advice on the experimental design	Conceived and designed the experiments	Methodology	YES
5405135	28491067	JW	2	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5405135	28491067	LC	2	performed phenotype measurements|analyzed all data	performed phenotype measurements	Performed the experiments	Investigation	YES
5405135	28491067	LC	2	performed phenotype measurements|analyzed all data	analyzed all data	Analyzed the data	Formal analysis	YES
5405135	28491067	QL	2	performed phenotype measurements	performed phenotype measurements	Performed the experiments	Investigation	YES
5405135	28491067	TF	2	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5456288	28933405	A.S.	PLoS52	conceived and designed the experiments|analyzed the data	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5456288	28933405	A.S.	PLoS52	conceived and designed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5456288	28933405	B.R.	PLoS52	conceived and designed the experiments|analyzed the data	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5456288	28933405	B.R.	PLoS52	conceived and designed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5456288	28933405	C.P.	PLoS52	contributed to blood samples obtention	contributed to blood samples obtention	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5456288	28933405	P.D.	PLoS52	contributed to blood samples obtention	contributed to blood samples obtention	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5456288	28933405	T.P.	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5456288	28933405	T.P.	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5456288	28933405	T.P.	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5456288	28933405	T.P.	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5456288	28933405	Y.B.	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
4974779	27495977	LYB	2	provided helpful suggestion in data analysis and manuscript revision	provided helpful suggestion in data analysis and manuscript revision	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
4974779	27495977	QianY	2	analyzed the sequencing data, performed qrt pcr validations and wrote the manuscript	analyzed the sequencing data, performed qrt pcr validations and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Validation|Writing - Original Draft	YES
4974779	27495977	QinY	2	provided helpful suggestion in data analysis and manuscript revision	provided helpful suggestion in data analysis and manuscript revision	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
4974779	27495977	XFL	2	provided helpful suggestion in data analysis and manuscript revision	provided helpful suggestion in data analysis and manuscript revision	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
2828398	20180975	AJB	2	conceived the project, supported project implementation, and helped draft the manuscript	conceived the project, supported project implementation, and helped draft the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
2828398	20180975	BL	2	analyzed data and helped draft and edit the manuscript	analyzed data and helped draft and edit the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
2828398	20180975	JP	2	conceived the project, supported project implementation, analyzed data, and wrote the manuscript	conceived the project, supported project implementation, analyzed data, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
2828398	20180975	KS	2	conceived the project, supported project implementation, analyzed data, and helped draft the manuscript	conceived the project, supported project implementation, analyzed data, and helped draft the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
2828398	20180975	MK	2	conceived the project, supported project implementation, and helped draft the manuscript	conceived the project, supported project implementation, and helped draft the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
2828398	20180975	MM	2	conceived the project, analyzed data, and helped draft the manuscript	conceived the project, analyzed data, and helped draft the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
2828398	20180975	MMP	2	conceived the project, supported project implementation, and helped draft the manuscript	conceived the project, supported project implementation, and helped draft the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
2828398	20180975	PM	2	conceived the project, collected the data, supported project implementation, analyzed data, and wrote the manuscript	conceived the project, collected the data, supported project implementation, analyzed data, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
2828398	20180975	SB	2	analyzed data and helped draft and edit the manuscript	analyzed data and helped draft and edit the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
2828398	20180975	SG	2	conceived the project, supported project implementation, analyzed data, and helped draft the manuscript	conceived the project, supported project implementation, analyzed data, and helped draft the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
2828398	20180975	SGS	2	supported project implementation, analyzed data, and helped draft the manuscript	supported project implementation, analyzed data, and helped draft the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5405136	28491065	AN	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5405136	28491065	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5405136	28491065	GA	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5405136	28491065	JP	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5405136	28491065	KJ	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5405136	28491065	SL	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5405136	28491065	YG	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5405136	28491065	YY	PLoS52	performed the experiments|analyzed the data|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5405136	28491065	YY	PLoS52	performed the experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5405136	28491065	YY	PLoS52	performed the experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
2829503	20181091	AP	2	proposed the dissemination of the information through a scientific article, assisted in data analysis, participated in the revision of the final manuscript and provided some useful comments	proposed the dissemination of the information through a scientific article, assisted in data analysis, participated in the revision of the final manuscript and provided some useful comments	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Review & Editing	YES
4974784	27496535	AG	2	conceived the study, participated in its design, coordinated the study, and reviewed the manuscript	conceived the study, participated in its design, coordinated the study, and reviewed the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Review & Editing	YES
4974784	27496535	EO	2	performed proteomics data acquisition and reviewed the manuscript	performed proteomics data acquisition and reviewed the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4974784	27496535	FB	2	performed proteomics data acquisition and reviewed the manuscript	performed proteomics data acquisition and reviewed the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4974784	27496535	FY	2	performed data analysis and wrote the manuscript	performed data analysis and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4974784	27496535	HKG	2	performed proteomics data acquisition and reviewed the manuscript	performed proteomics data acquisition and reviewed the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4974784	27496535	OAK	2	coordinated the project, participated in proteomics experiment design, data analysis, writing and review of the manuscript	coordinated the project, participated in proteomics experiment design, data analysis, writing and review of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Project administration|Writing - Original Draft|Writing - Review & Editing	YES
4974784	27496535	SB	2	participated in sample preparation and assays	participated in sample preparation and assays	Performed the experiments	Investigation	YES
2844355	20205937	All authors	2	reviewed, revised and approved the manuscript for submission	reviewed, revised and approved the manuscript for submission	Wrote the paper	Writing - Review & Editing	YES
2844355	20205937	CLM	2	participated in study design, data collection, analysis and writing of the manuscript	participated in study design, data collection, analysis and writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
2844355	20205937	GN	2	advised on study design, and participated in data collection, analysis and writing of the manuscript	advised on study design, and participated in data collection, analysis and writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
2844355	20205937	JR	2	conceived the study, developed the protocol, and participated in data collection, analysis and writing of the manuscript	conceived the study, developed the protocol, and participated in data collection, analysis and writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5456302	28933387	F.P.F.	2	were responsible for the conception and design of the study, coordinated all activities, and drafted the manuscript	were responsible for the conception and design of the study, coordinated all activities, and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
5456302	28933387	F.P.S.	2	were responsible for the conception and design of the study, coordinated all activities, and drafted the manuscript|supervised data collection and critically reviewed and revised the manuscript and approved the final manuscript	were responsible for the conception and design of the study, coordinated all activities, and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
5456302	28933387	F.P.S.	2	were responsible for the conception and design of the study, coordinated all activities, and drafted the manuscript|supervised data collection and critically reviewed and revised the manuscript and approved the final manuscript	supervised data collection and critically reviewed and revised the manuscript and approved the final manuscript	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Review & Editing	YES
5456302	28933387	F.S.	2	were responsible for the conception and design of the study, coordinated all activities, and drafted the manuscript|performed n|performed network analysis|supervised data collection and critically reviewed and revised the manuscript and approved the final manuscript	were responsible for the conception and design of the study, coordinated all activities, and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
5456302	28933387	F.S.	2	were responsible for the conception and design of the study, coordinated all activities, and drafted the manuscript|performed n|performed network analysis|supervised data collection and critically reviewed and revised the manuscript and approved the final manuscript	performed n	Performed the experiments	Investigation	YES
5456302	28933387	F.S.	2	were responsible for the conception and design of the study, coordinated all activities, and drafted the manuscript|performed n|performed network analysis|supervised data collection and critically reviewed and revised the manuscript and approved the final manuscript	performed network analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5456302	28933387	F.S.	2	were responsible for the conception and design of the study, coordinated all activities, and drafted the manuscript|performed n|performed network analysis|supervised data collection and critically reviewed and revised the manuscript and approved the final manuscript	supervised data collection and critically reviewed and revised the manuscript and approved the final manuscript	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Review & Editing	YES
5456302	28933387	G.L.	2	performed nephrectomy, pathological tumor staging and grading and performed data collection	performed nephrectomy, pathological tumor staging and grading and performed data collection	Performed the experiments	Investigation	YES
5456302	28933387	M.B.	2	performed nephrectomy, pathological tumor staging and grading and performed data collection|supervised data collection and critically reviewed and revised the manuscript and approved the final manuscript	performed nephrectomy, pathological tumor staging and grading and performed data collection	Performed the experiments	Investigation	YES
5456302	28933387	M.B.	2	performed nephrectomy, pathological tumor staging and grading and performed data collection|supervised data collection and critically reviewed and revised the manuscript and approved the final manuscript	supervised data collection and critically reviewed and revised the manuscript and approved the final manuscript	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Review & Editing	YES
5456302	28933387	M.R.	2	collected, analyzed, and interpreted the clinical data|statistical analysis	collected, analyzed, and interpreted the clinical data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5456302	28933387	M.R.	2	collected, analyzed, and interpreted the clinical data|statistical analysis	statistical analysis	Analyzed the data	Formal analysis	YES
5456302	28933387	P.D.T.	2	performed nephrectomy, pathological tumor staging and grading and performed data collection	performed nephrectomy, pathological tumor staging and grading and performed data collection	Performed the experiments	Investigation	YES
5456302	28933387	R.R.	2	were responsible for the conception and design of the study, coordinated all activities, and drafted the manuscript|performed n	were responsible for the conception and design of the study, coordinated all activities, and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
5456302	28933387	R.R.	2	were responsible for the conception and design of the study, coordinated all activities, and drafted the manuscript|performed n	performed n	Performed the experiments	Investigation	YES
5456302	28933387	S.P.	2	performed nephrectomy, pathological tumor staging and grading and performed data collection|performed n	performed nephrectomy, pathological tumor staging and grading and performed data collection	Performed the experiments	Investigation	YES
5456302	28933387	S.P.	2	performed nephrectomy, pathological tumor staging and grading and performed data collection|performed n	performed n	Performed the experiments	Investigation	YES
5456302	28933387	V.G.	2	collected, analyzed, and interpreted the clinical data	collected, analyzed, and interpreted the clinical data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5405137	28491071	AA	2	helped with samples and measurement preparation	helped with samples and measurement preparation	Performed the experiments	Investigation	YES
5405137	28491071	BF	2	designed the research, analyzed and interpreted data, and wrote the manuscript	designed the research, analyzed and interpreted data, and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5405137	28491071	EB	2	processed and analyzed spme-gc-ms data	processed and analyzed spme-gc-ms data	Analyzed the data	Data curation|Formal analysis	YES
5405137	28491071	FB	2	guided the ptr-tof-ms analysis and edited the manuscript	guided the ptr-tof-ms analysis and edited the manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
5405137	28491071	FG	2	guided the spme-gc-ms analysis and edited the manuscript	guided the spme-gc-ms analysis and edited the manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
5405137	28491071	IK	2	helped with measurements, processed, and analyzed ptr-tof-ms data	helped with measurements, processed, and analyzed ptr-tof-ms data	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5405137	28491071	LG	2	coordinated the work design, contributed to data interpretation, and edited the manuscript	coordinated the work design, contributed to data interpretation, and edited the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Project administration|Writing - Review & Editing	YES
5405137	28491071	MA	2	assessed the fruit quality analysis and sampled the blueberries	assessed the fruit quality analysis and sampled the blueberries	-	Validation	YES
2847986	20196856	RA	2	conceived the study and its design, undertook the analysis, and wrote the manuscript	conceived the study and its design, undertook the analysis, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Writing - Original Draft	YES
4974788	27495311	CAW	2	performed bioinformatic data analysis|contributed to the writing of the manuscript	performed bioinformatic data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4974788	27495311	CAW	2	performed bioinformatic data analysis|contributed to the writing of the manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
4974788	27495311	DM	2	performed bioinformatic data analysis|contributed to the writing of the manuscript	performed bioinformatic data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4974788	27495311	DM	2	performed bioinformatic data analysis|contributed to the writing of the manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
4974788	27495311	JB	2	performed bioinformatic data analysis	performed bioinformatic data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4974788	27495311	JCL	2	designed the experiment and wrote the manuscript|contributed to the writing of the manuscript|supervised the research	designed the experiment and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4974788	27495311	JCL	2	designed the experiment and wrote the manuscript|contributed to the writing of the manuscript|supervised the research	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
4974788	27495311	JCL	2	designed the experiment and wrote the manuscript|contributed to the writing of the manuscript|supervised the research	supervised the research	-	Supervision	YES
4974788	27495311	JW	2	performed data analysis to refine the genome annotations|performed bioinformatic data analysis|contributed to the writing of the manuscript	performed data analysis to refine the genome annotations	Analyzed the data	Data curation|Formal analysis	YES
4974788	27495311	JW	2	performed data analysis to refine the genome annotations|performed bioinformatic data analysis|contributed to the writing of the manuscript	performed bioinformatic data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4974788	27495311	JW	2	performed data analysis to refine the genome annotations|performed bioinformatic data analysis|contributed to the writing of the manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
4974788	27495311	KAS	2	performed the sample preparations for genomic and transcriptomic sequencing, including all cultivations|performed experiments for phenotypic characterization of gs115 strain|performed data analysis to refine the genome annotations|performed bioinformatic data analysis|designed the experiment and wrote the manuscript|contributed to the writing of the manuscript	performed the sample preparations for genomic and transcriptomic sequencing, including all cultivations	Performed the experiments	Investigation	YES
4974788	27495311	KAS	2	performed the sample preparations for genomic and transcriptomic sequencing, including all cultivations|performed experiments for phenotypic characterization of gs115 strain|performed data analysis to refine the genome annotations|performed bioinformatic data analysis|designed the experiment and wrote the manuscript|contributed to the writing of the manuscript	performed experiments for phenotypic characterization of gs115 strain	Performed the experiments	Investigation	YES
4974788	27495311	KAS	2	performed the sample preparations for genomic and transcriptomic sequencing, including all cultivations|performed experiments for phenotypic characterization of gs115 strain|performed data analysis to refine the genome annotations|performed bioinformatic data analysis|designed the experiment and wrote the manuscript|contributed to the writing of the manuscript	performed data analysis to refine the genome annotations	Analyzed the data	Data curation|Formal analysis	YES
4974788	27495311	KAS	2	performed the sample preparations for genomic and transcriptomic sequencing, including all cultivations|performed experiments for phenotypic characterization of gs115 strain|performed data analysis to refine the genome annotations|performed bioinformatic data analysis|designed the experiment and wrote the manuscript|contributed to the writing of the manuscript	performed bioinformatic data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4974788	27495311	KAS	2	performed the sample preparations for genomic and transcriptomic sequencing, including all cultivations|performed experiments for phenotypic characterization of gs115 strain|performed data analysis to refine the genome annotations|performed bioinformatic data analysis|designed the experiment and wrote the manuscript|contributed to the writing of the manuscript	designed the experiment and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4974788	27495311	KAS	2	performed the sample preparations for genomic and transcriptomic sequencing, including all cultivations|performed experiments for phenotypic characterization of gs115 strain|performed data analysis to refine the genome annotations|performed bioinformatic data analysis|designed the experiment and wrote the manuscript|contributed to the writing of the manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
4974788	27495311	KRL	2	performed bioinformatic data analysis|designed the experiment and wrote the manuscript|contributed to the writing of the manuscript|supervised the research	performed bioinformatic data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4974788	27495311	KRL	2	performed bioinformatic data analysis|designed the experiment and wrote the manuscript|contributed to the writing of the manuscript|supervised the research	designed the experiment and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4974788	27495311	KRL	2	performed bioinformatic data analysis|designed the experiment and wrote the manuscript|contributed to the writing of the manuscript|supervised the research	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
4974788	27495311	KRL	2	performed bioinformatic data analysis|designed the experiment and wrote the manuscript|contributed to the writing of the manuscript|supervised the research	supervised the research	-	Supervision	YES
4974788	27495311	MCB	2	performed bioinformatic data analysis|contributed to the writing of the manuscript	performed bioinformatic data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4974788	27495311	MCB	2	performed bioinformatic data analysis|contributed to the writing of the manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
4974788	27495311	MP	2	developed the sequencing approach and performed initial genome annotations	developed the sequencing approach and performed initial genome annotations	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
4974788	27495311	RL	2	performed the sample preparations for genomic and transcriptomic sequencing, including all cultivations	performed the sample preparations for genomic and transcriptomic sequencing, including all cultivations	Performed the experiments	Investigation	YES
4974788	27495311	SKY	2	developed the sequencing approach and performed initial genome annotations	developed the sequencing approach and performed initial genome annotations	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
4381569	25866813	Jolanta Opiela	2	contributed equally to the preparation of this paper	contributed equally to the preparation of this paper	-	-	NO
4381569	25866813	Marcin Samiec	2	contributed equally to the preparation of this paper	contributed equally to the preparation of this paper	-	-	NO
5456303	28933383	A.G.	4	cytotoxicity assays and related data analysis was carried out by	cytotoxicity assays and related data analysis was carried out by	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5456303	28933383	G.L.	4	cytotoxicity assays and related data analysis was carried out by	cytotoxicity assays and related data analysis was carried out by	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5456303	28933383	J.J.E.M.	4	Plant materials were collected by|Spectroscopic identification of the pure compounds was carried out by|The manuscript was prepared by	Plant materials were collected by	Performed the experiments	Investigation	YES
5456303	28933383	J.J.E.M.	4	Plant materials were collected by|Spectroscopic identification of the pure compounds was carried out by|The manuscript was prepared by	Spectroscopic identification of the pure compounds was carried out by	Performed the experiments	Investigation	YES
5456303	28933383	J.J.E.M.	4	Plant materials were collected by|Spectroscopic identification of the pure compounds was carried out by|The manuscript was prepared by	The manuscript was prepared by	Wrote the paper	Writing - Original Draft	YES
5456303	28933383	M.E.	4	Spectroscopic identification of the pure compounds was carried out by|The manuscript was prepared by	Spectroscopic identification of the pure compounds was carried out by	Performed the experiments	Investigation	YES
5456303	28933383	M.E.	4	Spectroscopic identification of the pure compounds was carried out by|The manuscript was prepared by	The manuscript was prepared by	Wrote the paper	Writing - Original Draft	YES
5456303	28933383	P.A.	4	the root barks by|The constituents of the stem and root barks were purified by|Spectroscopic identification of the pure compounds was carried out by	the root barks by	-	-	NO
5456303	28933383	P.A.	4	the root barks by|The constituents of the stem and root barks were purified by|Spectroscopic identification of the pure compounds was carried out by	The constituents of the stem and root barks were purified by	Performed the experiments	Investigation	YES
5456303	28933383	P.A.	4	the root barks by|The constituents of the stem and root barks were purified by|Spectroscopic identification of the pure compounds was carried out by	Spectroscopic identification of the pure compounds was carried out by	Performed the experiments	Investigation	YES
5456303	28933383	P.A.F.	4	cytotoxicity assays and related data analysis was carried out by	cytotoxicity assays and related data analysis was carried out by	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5456303	28933383	S.S.N.	4	Plant materials were collected by|Stem barks were extracxted by|dpph assay and data analysis was carried out by|The manuscript was prepared by	Plant materials were collected by	Performed the experiments	Investigation	YES
5456303	28933383	S.S.N.	4	Plant materials were collected by|Stem barks were extracxted by|dpph assay and data analysis was carried out by|The manuscript was prepared by	Stem barks were extracxted by	-	-	NO
5456303	28933383	S.S.N.	4	Plant materials were collected by|Stem barks were extracxted by|dpph assay and data analysis was carried out by|The manuscript was prepared by	dpph assay and data analysis was carried out by	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5456303	28933383	S.S.N.	4	Plant materials were collected by|Stem barks were extracxted by|dpph assay and data analysis was carried out by|The manuscript was prepared by	The manuscript was prepared by	Wrote the paper	Writing - Original Draft	YES
2847987	20205930	AM	2	contributed to the design of the study, assisted in analyzing and interpreting the data, and contributed to editing the manuscript	contributed to the design of the study, assisted in analyzing and interpreting the data, and contributed to editing the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Review & Editing	YES
2847987	20205930	All authors	2	have given final approval for the manuscript	have given final approval for the manuscript	-	-	NO
2847987	20205930	BS	2	contributed to interpreting the data and to the final manuscript	contributed to interpreting the data and to the final manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
2847987	20205930	DC	2	oversaw data collection, assisted in interpreting the data, and contributed to editing the manuscript	oversaw data collection, assisted in interpreting the data, and contributed to editing the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Supervision|Writing - Review & Editing	YES
2847987	20205930	MF	2	contributed to the design of the study, analyzed the data, and wrote the first draft of the manuscript	contributed to the design of the study, analyzed the data, and wrote the first draft of the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Original Draft	YES
2847987	20205930	PS	2	assisted in analyzing and interpreting the data, and contributed to editing the manuscript	assisted in analyzing and interpreting the data, and contributed to editing the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
2847987	20205930	SR	2	contributed to the design of the study and the interpretation of the data, and contributed to writing the first manuscript	contributed to the design of the study and the interpretation of the data, and contributed to writing the first manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Original Draft	YES
4974801	27495742	FMA	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4974801	27495742	FMA	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4974801	27495742	MFL	PLoS5	Conceived and designed experiments	Conceived and designed experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4974801	27495742	NTG	PLoS5	Conceived and designed experiments|Analyzed the data|Wrote the paper	Conceived and designed experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4974801	27495742	NTG	PLoS5	Conceived and designed experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4974801	27495742	NTG	PLoS5	Conceived and designed experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5405143	28491068	All authors	2	listed, have made substantial, direct and intellectual contribution to the work, and approved it for publication	listed, have made substantial, direct and intellectual contribution to the work, and approved it for publication	-	-	NO
5456304	28933389	B.J.T.	PLoS52	collected the data|assisted with editing and manuscript preparation	collected the data	Performed the experiments	Investigation	YES
5456304	28933389	B.J.T.	PLoS52	collected the data|assisted with editing and manuscript preparation	assisted with editing and manuscript preparation	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5456304	28933389	J.T.	PLoS52	analyzed the data|assisted with editing and manuscript preparation	analyzed the data	Analyzed the data	Formal analysis	YES
5456304	28933389	J.T.	PLoS52	analyzed the data|assisted with editing and manuscript preparation	assisted with editing and manuscript preparation	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5456304	28933389	K.M.G.	PLoS52	collected the data|assisted with editing and manuscript preparation	collected the data	Performed the experiments	Investigation	YES
5456304	28933389	K.M.G.	PLoS52	collected the data|assisted with editing and manuscript preparation	assisted with editing and manuscript preparation	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5456304	28933389	L.J.R.	PLoS52	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5456304	28933389	P.H.	PLoS52	conceived and designed the experiment|assisted with editing and manuscript preparation	conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5456304	28933389	P.H.	PLoS52	conceived and designed the experiment|assisted with editing and manuscript preparation	assisted with editing and manuscript preparation	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5456304	28933389	S.E.	PLoS52	conceived and designed the experiment|collected the data|assisted with editing and manuscript preparation	conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5456304	28933389	S.E.	PLoS52	conceived and designed the experiment|collected the data|assisted with editing and manuscript preparation	collected the data	Performed the experiments	Investigation	YES
5456304	28933389	S.E.	PLoS52	conceived and designed the experiment|collected the data|assisted with editing and manuscript preparation	assisted with editing and manuscript preparation	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
2851580	20230628	AT	2	contributed to the data analysis and manuscript preparation	contributed to the data analysis and manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
2851580	20230628	BV	2	assisted with data collection as the study physician in zambia and contributed to the study design and implementation	assisted with data collection as the study physician in zambia and contributed to the study design and implementation	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
2851580	20230628	EK	2	is the rzhrg director in kigali and directed the study at the kigali clinics	is the rzhrg director in kigali and directed the study at the kigali clinics	-	Supervision	YES
2851580	20230628	ES	2	assisted with this study in kigali, rwanda, and lusaka, zambia, and conducted the preliminary analyses, writing and literature review	assisted with this study in kigali, rwanda, and lusaka, zambia, and conducted the preliminary analyses, writing and literature review	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
2851580	20230628	HIV	2	research project and oversaw the study activities in lusaka, zambia	research project and oversaw the study activities in lusaka, zambia	-	Supervision	YES
2851580	20230628	MC	2	led the writing, editing and submission of the article, and the final analysis of the data	led the writing, editing and submission of the article, and the final analysis of the data	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
2851580	20230628	MS	2	was the director of the lusaka district health management team in zambia and facilitated the study conduct and clinic staff availability in lusaka	was the director of the lusaka district health management team in zambia and facilitated the study conduct and clinic staff availability in lusaka	Performed the experiments	Investigation|Project administration	YES
2851580	20230628	SA	2	based at emory university, is the director of the rzhrg and was the principal investigator for the world aids foundation grant|wrote the study grant and coordinated the research in both kigali and lusaka	based at emory university, is the director of the rzhrg and was the principal investigator for the world aids foundation grant	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
2851580	20230628	SA	2	based at emory university, is the director of the rzhrg and was the principal investigator for the world aids foundation grant|wrote the study grant and coordinated the research in both kigali and lusaka	wrote the study grant and coordinated the research in both kigali and lusaka	Wrote the paper	Project administration|Writing - Original Draft	YES
4974804	27495169	AAMCL	2	conceived and designed the experiments, analyzed the data, contributed data/materials/analysis tools, wrote the manuscript	conceived and designed the experiments, analyzed the data, contributed data/materials/analysis tools, wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Methodology|Resources|Writing - Original Draft	YES
4974804	27495169	AJL	2	contributed data/materials/analysis tools	contributed data/materials/analysis tools	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
4974804	27495169	AMD	2	conceived and designed the experiments, analyzed the data, contributed data/materials/analysis tools, wrote the manuscript	conceived and designed the experiments, analyzed the data, contributed data/materials/analysis tools, wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Methodology|Resources|Writing - Original Draft	YES
4974804	27495169	BJL	2	conceived and designed the experiments, analyzed the data, contributed data/materials/analysis tools, wrote the manuscript	conceived and designed the experiments, analyzed the data, contributed data/materials/analysis tools, wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Methodology|Resources|Writing - Original Draft	YES
4974804	27495169	PMS	2	conceived and designed the experiments, analyzed the data, contributed data/materials/analysis tools, wrote the manuscript	conceived and designed the experiments, analyzed the data, contributed data/materials/analysis tools, wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Methodology|Resources|Writing - Original Draft	YES
5456305	28933392	Annamaria Mazzone	2	made substantial contributions to manuscript and approved the final version of the manuscript	made substantial contributions to manuscript and approved the final version of the manuscript	-	-	NO
5456305	28933392	Clara Carpeggiani	2	made substantial contributions to manuscript and approved the final version of the manuscript	made substantial contributions to manuscript and approved the final version of the manuscript	-	-	NO
5456305	28933392	Cristina Vassalle	2	make essential contribution to manuscript conception taking responsibility in the construction of the body of the manuscript	make essential contribution to manuscript conception taking responsibility in the construction of the body of the manuscript	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
2851581	20302672	CST	2	carried out the study and collected data in the field	carried out the study and collected data in the field	Performed the experiments	Investigation	YES
2851581	20302672	EA	2	carried out the study and collected data in the field	carried out the study and collected data in the field	Performed the experiments	Investigation	YES
2851581	20302672	EN	2	did the virological evaluation	did the virological evaluation	-	-	NO
2851581	20302672	KA	2	carried out the study and collected data in the field	carried out the study and collected data in the field	Performed the experiments	Investigation	YES
2851581	20302672	MER	2	conceived and designed the study protocol|did the statistical analysis	conceived and designed the study protocol	Conceived and designed the experiments	Conceptualization|Methodology	YES
2851581	20302672	MER	2	conceived and designed the study protocol|did the statistical analysis	did the statistical analysis	Analyzed the data	Formal analysis	YES
2851581	20302672	PI	2	conceived and designed the study protocol|was the study coordinator|participated in the statistical analysis and data interpretation|led the writing of the manuscript	conceived and designed the study protocol	Conceived and designed the experiments	Conceptualization|Methodology	YES
2851581	20302672	PI	2	conceived and designed the study protocol|was the study coordinator|participated in the statistical analysis and data interpretation|led the writing of the manuscript	was the study coordinator	-	Project administration	YES
2851581	20302672	PI	2	conceived and designed the study protocol|was the study coordinator|participated in the statistical analysis and data interpretation|led the writing of the manuscript	participated in the statistical analysis and data interpretation	Analyzed the data	Formal analysis	YES
2851581	20302672	PI	2	conceived and designed the study protocol|was the study coordinator|participated in the statistical analysis and data interpretation|led the writing of the manuscript	led the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
2851581	20302672	RZ	2	participated in the statistical analysis and data interpretation	participated in the statistical analysis and data interpretation	Analyzed the data	Formal analysis	YES
2851581	20302672	SN	2	did the virological evaluation	did the virological evaluation	-	-	NO
2851581	20302672	TV	2	carried out the study and collected data in the field	carried out the study and collected data in the field	Performed the experiments	Investigation	YES
2851581	20302672	VK	2	carried out the study and collected data in the field	carried out the study and collected data in the field	Performed the experiments	Investigation	YES
5405147	28491070	MA	2	reviewed and updated the manuscript	reviewed and updated the manuscript	Wrote the paper	Writing - Review & Editing	YES
5405324	28491077	All authors	2	listed, have made substantial, direct and intellectual contribution to the work, and approved it for publication	listed, have made substantial, direct and intellectual contribution to the work, and approved it for publication	-	-	NO
2859852	20307322	ADS	2	assisted in the interpretation of study findings and critical revision of the manuscript	assisted in the interpretation of study findings and critical revision of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
2859852	20307322	AIS	2	assisted in collecting data and creating the database, the interpretation of study findings, and the critical revision the manuscript	assisted in collecting data and creating the database, the interpretation of study findings, and the critical revision the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Software|Writing - Review & Editing	YES
2859852	20307322	DAA	2	assisted in collecting data and creating the database, the interpretation of study findings, and the critical revision the manuscript	assisted in collecting data and creating the database, the interpretation of study findings, and the critical revision the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Software|Writing - Review & Editing	YES
2859852	20307322	JJJ	2	was responsible for study concept and design, data analysis, interpretation of the study findings, and manuscript writing	was responsible for study concept and design, data analysis, interpretation of the study findings, and manuscript writing	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
2859852	20307322	JWO	2	assisted in the interpretation of study findings and critical revision of the manuscript	assisted in the interpretation of study findings and critical revision of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
2859852	20307322	MJK	2	assisted in the interpretation of study findings and critical revision of the manuscript	assisted in the interpretation of study findings and critical revision of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
2859852	20307322	MW	2	assisted in data and statistical analysis, interpretation of study findings, and the critical revision of the final manuscript	assisted in data and statistical analysis, interpretation of study findings, and the critical revision of the final manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5456306	28933386	All authors	2	critically reviewed and approved the final manuscript	critically reviewed and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5456306	28933386	L.G.	2	wrote the effects in humans	wrote the effects in humans	Wrote the paper	Writing - Original Draft	YES
4975890	27496166	FC	2	contributed to data analysis, normalization of the sequencing data, and dendogram clustering of samples|participated in the design of the study	contributed to data analysis, normalization of the sequencing data, and dendogram clustering of samples	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4975890	27496166	FC	2	contributed to data analysis, normalization of the sequencing data, and dendogram clustering of samples|participated in the design of the study	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
4975890	27496166	JB	2	carried out the sequencing experiment, data analysis, and fig|participated in the design of the study|wrote the manuscript	carried out the sequencing experiment, data analysis, and fig	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4975890	27496166	JB	2	carried out the sequencing experiment, data analysis, and fig|participated in the design of the study|wrote the manuscript	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
4975890	27496166	JB	2	carried out the sequencing experiment, data analysis, and fig|participated in the design of the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4975890	27496166	SM	2	carried out qrt-pcr experiments	carried out qrt-pcr experiments	Performed the experiments	Investigation	YES
4975890	27496166	SW	2	participated in the design of the study|wrote the manuscript	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
4975890	27496166	SW	2	participated in the design of the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4975890	27496166	YL	2	contributed to data analysis, normalization of the sequencing data, and dendogram clustering of samples	contributed to data analysis, normalization of the sequencing data, and dendogram clustering of samples	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
2868805	20409346	ACF	2	conducted the extensive literature search, collated available data, produced the figures and wrote the first draft of the manuscript	conducted the extensive literature search, collated available data, produced the figures and wrote the first draft of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Formal analysis|Investigation|Visualization|Writing - Original Draft	YES
2868805	20409346	DPW	2	conceived and supervised the review project and contributed to the writing of the manuscript	conceived and supervised the review project and contributed to the writing of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
5405695	28491069	AW	2	designed c	designed c	Conceived and designed the experiments	-	YES
5405695	28491069	DS	2	designed the research|performed homology searches for h3k27me3 targets used in chip-rt-qpcr	designed the research	Conceived and designed the experiments	Methodology	YES
5405695	28491069	DS	2	designed the research|performed homology searches for h3k27me3 targets used in chip-rt-qpcr	performed homology searches for h3k27me3 targets used in chip-rt-qpcr	Performed the experiments	Investigation	YES
5405695	28491069	FF	2	designed c	designed c	Conceived and designed the experiments	-	YES
5405695	28491069	OK	2	designed the research|performed competition assay and western blot experiments	designed the research	Conceived and designed the experiments	Methodology	YES
5405695	28491069	OK	2	designed the research|performed competition assay and western blot experiments	performed competition assay and western blot experiments	Performed the experiments	Investigation	YES
5405695	28491069	PM	2	designed the research|performed bioinformatic analyses, chromatin immunoprecipitations and sequencing library preparations|performed homology searches for h3k27me3 targets used in chip-rt-qpcr|revised by the other authors	designed the research	Conceived and designed the experiments	Methodology	YES
5405695	28491069	PM	2	designed the research|performed bioinformatic analyses, chromatin immunoprecipitations and sequencing library preparations|performed homology searches for h3k27me3 targets used in chip-rt-qpcr|revised by the other authors	performed bioinformatic analyses, chromatin immunoprecipitations and sequencing library preparations	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5405695	28491069	PM	2	designed the research|performed bioinformatic analyses, chromatin immunoprecipitations and sequencing library preparations|performed homology searches for h3k27me3 targets used in chip-rt-qpcr|revised by the other authors	performed homology searches for h3k27me3 targets used in chip-rt-qpcr	Performed the experiments	Investigation	YES
5405695	28491069	PM	2	designed the research|performed bioinformatic analyses, chromatin immunoprecipitations and sequencing library preparations|performed homology searches for h3k27me3 targets used in chip-rt-qpcr|revised by the other authors	revised by the other authors	Wrote the paper	Writing - Review & Editing	YES
4381848	25866784	Huacheng Hou	2	are the authors making the equal contribution	are the authors making the equal contribution	-	-	NO
4381848	25866784	Ke Zheng	2	are the authors making the equal contribution	are the authors making the equal contribution	-	-	NO
2873546	20398261	AV	2	designed the study questionnaire and critically reviewed the manuscript	designed the study questionnaire and critically reviewed the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
2873546	20398261	FvG	2	designed the study and wrote the first version of the manuscript	designed the study and wrote the first version of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
2873546	20398261	PM	2	oversaw database management and statistical analysis	oversaw database management and statistical analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Software|Supervision	YES
2873546	20398261	SC	2	oversaw the execution of the study and collection of data	oversaw the execution of the study and collection of data	Performed the experiments	Investigation|Supervision	YES
2873546	20398261	WS	2	programmed the questionnaire and managed the data	programmed the questionnaire and managed the data	Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Software	YES
2873546	20398261	WT	2	performed statistical analysis and reviewed the manuscript	performed statistical analysis and reviewed the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
2873546	20398261	WW	2	oversaw the recruitment and retention of study participants and performed statistical analysis	oversaw the recruitment and retention of study participants and performed statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Supervision	YES
5456307	28933395	Kazuki Mochizuki	2	were responsible for editing and assistance with manuscript preparation	were responsible for editing and assistance with manuscript preparation	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5456307	28933395	Kunio Miyake	2	were responsible for editing and assistance with manuscript preparation	were responsible for editing and assistance with manuscript preparation	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5456307	28933395	Natsuyo Hariya	2	were responsible for editing and assistance with manuscript preparation	were responsible for editing and assistance with manuscript preparation	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5456307	28933395	Takeo Kubota	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5456307	28933395	Vuong Tran Nguyen	2	were responsible for editing and assistance with manuscript preparation	were responsible for editing and assistance with manuscript preparation	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4975902	27496222	JS	2	helped in data analysis	helped in data analysis	Analyzed the data	Formal analysis	YES
4975902	27496222	JW	2	carried out the analysis and drafted the manuscript	carried out the analysis and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4975902	27496222	QL	2	conceived of the study, guided the analysis, and revised the manuscript	conceived of the study, guided the analysis, and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Supervision|Writing - Review & Editing	YES
4975902	27496222	YS	2	supervised the research	supervised the research	-	Supervision	YES
2876070	20406460	AS	2	participated in the study design, data collection, and revisions of the manuscript	participated in the study design, data collection, and revisions of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
2876070	20406460	ES	2	contributed to the study design and revisions of the manuscript	contributed to the study design and revisions of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
2876070	20406460	KL	2	conceived the study design, supervised and participated in the data collection and psychological evaluation of subjects, participated in the statistical analysis, and drafted the manuscript	conceived the study design, supervised and participated in the data collection and psychological evaluation of subjects, participated in the statistical analysis, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Supervision|Writing - Original Draft	YES
2876070	20406460	KS	2	participated in the data collection, psychological evaluation of subjects, and revisions of the manuscript	participated in the data collection, psychological evaluation of subjects, and revisions of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
2876070	20406460	MM	2	participated in the study design, provided supervision for the overall collection of data in the infectious disease care clinic, and undertook revisions of the manuscript	participated in the study design, provided supervision for the overall collection of data in the infectious disease care clinic, and undertook revisions of the manuscript	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Methodology|Resources|Supervision|Writing - Review & Editing	YES
2876070	20406460	RN	2	participated in the data collection and psychological evaluation of subjects	participated in the data collection and psychological evaluation of subjects	Performed the experiments	Investigation	YES
2876070	20406460	SR	2	participated in the study design and provided statistical analysis and interpretation of data	participated in the study design and provided statistical analysis and interpretation of data	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Methodology|Resources	YES
5406401	28496455	BZ	2	conceived of the study, and participated in its design|acquired of funding	conceived of the study, and participated in its design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5406401	28496455	BZ	2	conceived of the study, and participated in its design|acquired of funding	acquired of funding	-	Funding acquisition	YES
5406401	28496455	CS	2	helped to draft the manuscript	helped to draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5406401	28496455	DX	2	carried out the molecular studies, participated in the analysis and drafted the manuscript	carried out the molecular studies, participated in the analysis and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5406401	28496455	DY	2	conceived of the study, and participated in its design	conceived of the study, and participated in its design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5406401	28496455	HL	2	performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
5406401	28496455	HY	2	carried out the molecular studies, participated in the analysis and drafted the manuscript	carried out the molecular studies, participated in the analysis and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5406401	28496455	LQ	2	carried out the molecular studies, participated in the analysis and drafted the manuscript	carried out the molecular studies, participated in the analysis and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5406401	28496455	LZ	2	carried out the molecular studies, participated in the analysis and drafted the manuscript	carried out the molecular studies, participated in the analysis and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5406401	28496455	WG	2	carried out the qrt-pcr analysis	carried out the qrt-pcr analysis	Performed the experiments	Investigation	YES
5406401	28496455	YT	2	carried out the molecular studies, participated in the analysis and drafted the manuscript	carried out the molecular studies, participated in the analysis and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
2880016	20406455	ESS	2	participated in the initial development of the study, developed the instrument for the study, collected the data and made inputs into the various versions of the revised manuscript	participated in the initial development of the study, developed the instrument for the study, collected the data and made inputs into the various versions of the revised manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
2880016	20406455	NOA	2	designed the study, collected the data and analysed it, developed the manuscript including subsequent revisions of the manuscript	designed the study, collected the data and analysed it, developed the manuscript including subsequent revisions of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
2880252	20519022	RK	2	drafted this text and approved the manuscript for publication	drafted this text and approved the manuscript for publication	Wrote the paper	Writing - Original Draft	YES
4977621	27506675	AJ	2	performed the cell culture based study	performed the cell culture based study	Performed the experiments	Investigation	YES
4977621	27506675	All the authors	2	participated for the writing of the paper and agreed to the final variant of the manuscript	participated for the writing of the paper and agreed to the final variant of the manuscript	Wrote the paper	Writing - Original Draft	YES
4977621	27506675	CB	2	carried out the microarray study	carried out the microarray study	Performed the experiments	Investigation	YES
4977621	27506675	DEM	2	performed the cell culture based study	performed the cell culture based study	Performed the experiments	Investigation	YES
4977621	27506675	IBN	2	carried out the microarray study	carried out the microarray study	Performed the experiments	Investigation	YES
4977621	27506675	IT	2	performed the cell culture based study	performed the cell culture based study	Performed the experiments	Investigation	YES
4977621	27506675	MM	2	performed the cell culture based study	performed the cell culture based study	Performed the experiments	Investigation	YES
4977621	27506675	OB	2	performed the cell performed microarray statistical analysis	performed the cell performed microarray statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4977621	27506675	PAC	2	carried out the microarray study	carried out the microarray study	Performed the experiments	Investigation	YES
4977621	27506675	RCP	2	performed the cell performed microarray statistical analysis	performed the cell performed microarray statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4977621	27506675	RL	2	performed the cell performed microarray statistical analysis	performed the cell performed microarray statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4977621	27506675	SS	2	performed the cell performed microarray statistical analysis	performed the cell performed microarray statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
2880253	20519023	MM	2	drafted the initial text	drafted the initial text	Wrote the paper	Writing - Original Draft	YES
2880253	20519023	RK	2	adapted the text for publication in a peer-reviewed journal	adapted the text for publication in a peer-reviewed journal	Wrote the paper	Writing - Review & Editing	YES
5406457	28496451	All authors	2	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5406457	28496451	CL	2	performed the experiments, collected, and analyzed the data	performed the experiments, collected, and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5406457	28496451	JL	2	contributed to designing the experiments|contributed to data interpretation and preparation of the manuscript	contributed to designing the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5406457	28496451	JL	2	contributed to designing the experiments|contributed to data interpretation and preparation of the manuscript	contributed to data interpretation and preparation of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5406457	28496451	MP	2	contributed to designing the experiments|performed the experiments, collected, and analyzed the data|contributed to data interpretation and preparation of the manuscript	contributed to designing the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5406457	28496451	MP	2	contributed to designing the experiments|performed the experiments, collected, and analyzed the data|contributed to data interpretation and preparation of the manuscript	performed the experiments, collected, and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5406457	28496451	MP	2	contributed to designing the experiments|performed the experiments, collected, and analyzed the data|contributed to data interpretation and preparation of the manuscript	contributed to data interpretation and preparation of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5406457	28496451	MZ	2	contributed to designing the experiments|performed the experiments, collected, and analyzed the data|contributed to data interpretation and preparation of the manuscript	contributed to designing the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5406457	28496451	MZ	2	contributed to designing the experiments|performed the experiments, collected, and analyzed the data|contributed to data interpretation and preparation of the manuscript	performed the experiments, collected, and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5406457	28496451	MZ	2	contributed to designing the experiments|performed the experiments, collected, and analyzed the data|contributed to data interpretation and preparation of the manuscript	contributed to data interpretation and preparation of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5406457	28496451	PY	2	performed the experiments, collected, and analyzed the data	performed the experiments, collected, and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5406457	28496451	RX	2	contributed to data interpretation and preparation of the manuscript	contributed to data interpretation and preparation of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5406457	28496451	XL	2	contributed to data interpretation and preparation of the manuscript	contributed to data interpretation and preparation of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5456310	28933384	Daniel Judelson	7	Editing and assistance with manuscript preparation and data collection	Editing and assistance with manuscript preparation and data collection	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5456310	28933384	Daniela Rubin	7	Editing and assistance with manuscript preparation and data collection	Editing and assistance with manuscript preparation and data collection	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5456310	28933384	Diobel Castner	7	Primary author--wrote the manuscript and data collection	Primary author--wrote the manuscript and data collection	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5456310	28933384	Susan Clark	7	Editing manuscript and data collection	Editing manuscript and data collection	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
2880254	20519024	MM	2	drafted the initial text	drafted the initial text	Wrote the paper	Writing - Original Draft	YES
2880254	20519024	RK	2	adapted the text for publication in a peer-reviewed journal	adapted the text for publication in a peer-reviewed journal	Wrote the paper	Writing - Review & Editing	YES
4977635	27507588	BCL	PLoS52	performed the research|analysed the data|wrote the paper	performed the research	Performed the experiments	Investigation	YES
4977635	27507588	BCL	PLoS52	performed the research|analysed the data|wrote the paper	analysed the data	Analyzed the data	Formal analysis	YES
4977635	27507588	BCL	PLoS52	performed the research|analysed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4977635	27507588	HC	PLoS52	performed the research|analysed the data|wrote the paper	performed the research	Performed the experiments	Investigation	YES
4977635	27507588	HC	PLoS52	performed the research|analysed the data|wrote the paper	analysed the data	Analyzed the data	Formal analysis	YES
4977635	27507588	HC	PLoS52	performed the research|analysed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4977635	27507588	SLK	PLoS52	performed the research|analysed the data|wrote the paper	performed the research	Performed the experiments	Investigation	YES
4977635	27507588	SLK	PLoS52	performed the research|analysed the data|wrote the paper	analysed the data	Analyzed the data	Formal analysis	YES
4977635	27507588	SLK	PLoS52	performed the research|analysed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4977635	27507588	SMK	PLoS52	performed the research|analysed the data|wrote the paper	performed the research	Performed the experiments	Investigation	YES
4977635	27507588	SMK	PLoS52	performed the research|analysed the data|wrote the paper	analysed the data	Analyzed the data	Formal analysis	YES
4977635	27507588	SMK	PLoS52	performed the research|analysed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4977635	27507588	WKC	PLoS52	designed the research|analysed the data|wrote the paper	designed the research	Conceived and designed the experiments	Methodology	YES
4977635	27507588	WKC	PLoS52	designed the research|analysed the data|wrote the paper	analysed the data	Analyzed the data	Formal analysis	YES
4977635	27507588	WKC	PLoS52	designed the research|analysed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4977635	27507588	YJ	PLoS52	designed the research|performed the research|analysed the data|wrote the paper	designed the research	Conceived and designed the experiments	Methodology	YES
4977635	27507588	YJ	PLoS52	designed the research|performed the research|analysed the data|wrote the paper	performed the research	Performed the experiments	Investigation	YES
4977635	27507588	YJ	PLoS52	designed the research|performed the research|analysed the data|wrote the paper	analysed the data	Analyzed the data	Formal analysis	YES
4977635	27507588	YJ	PLoS52	designed the research|performed the research|analysed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
2880255	20519025	RA	2	provided editorial input and advice	provided editorial input and advice	-	-	NO
2880255	20519025	RK	2	adapted the text for publication in a peer-reviewed journal	adapted the text for publication in a peer-reviewed journal	Wrote the paper	Writing - Review & Editing	YES
5456313	28933390	A.B.	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5456313	28933390	A.T.T.	2	contributed ideas to the manuscript	contributed ideas to the manuscript	Conceived and designed the experiments	Conceptualization	YES
5456313	28933390	L.L.	2	contributed ideas to the manuscript	contributed ideas to the manuscript	Conceived and designed the experiments	Conceptualization	YES
5456313	28933390	S.K.	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
2880256	20519026	RK	2	drafted the initial text, adapted it for publication in a peer-reviewed journal, and approved the manuscript for publication	drafted the initial text, adapted it for publication in a peer-reviewed journal, and approved the manuscript for publication	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5406470	28496449	JG	2	performed the gene expression analysis and interpretation|drafted the manuscript	performed the gene expression analysis and interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5406470	28496449	JG	2	performed the gene expression analysis and interpretation|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5406470	28496449	JI	2	designed the study|drafted the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5406470	28496449	JI	2	designed the study|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5406470	28496449	JT	2	performed phenotyping analysis	performed phenotyping analysis	Performed the experiments	Investigation	YES
5406470	28496449	NL	2	performed phenotyping analysis	performed phenotyping analysis	Performed the experiments	Investigation	YES
5456314	28933385	A.K.L.-H.	2	reviewed drafts of the manuscript	reviewed drafts of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5456314	28933385	All authors	2	were involved in the idea for the paper and in the review and preparation of the final manuscript	were involved in the idea for the paper and in the review and preparation of the final manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
5456314	28933385	M.G.S.	2	reviewed drafts of the manuscript	reviewed drafts of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5456314	28933385	O.S.E.	2	performed the literature review and wrote the paper	performed the literature review and wrote the paper	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
4977637	27502401	KH	2	conceived of the study and its design|performed the phenotyping assays, rna extractions, qrt pcr and rnai knockdowns|analyzed the rna seq data	conceived of the study and its design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4977637	27502401	KH	2	conceived of the study and its design|performed the phenotyping assays, rna extractions, qrt pcr and rnai knockdowns|analyzed the rna seq data	performed the phenotyping assays, rna extractions, qrt pcr and rnai knockdowns	Performed the experiments	Investigation	YES
4977637	27502401	KH	2	conceived of the study and its design|performed the phenotyping assays, rna extractions, qrt pcr and rnai knockdowns|analyzed the rna seq data	analyzed the rna seq data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4977637	27502401	SH	2	conceived of the study and its design|analyzed the rna seq data	conceived of the study and its design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4977637	27502401	SH	2	conceived of the study and its design|analyzed the rna seq data	analyzed the rna seq data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
2888781	20482807	All authors	2	approved the final draft of the work	approved the final draft of the work	Wrote the paper	Writing - Original Draft	YES
2888781	20482807	CIE	2	conceived the study and, with the other authors, participated in the design, data collection, analysis and interpretation of the results	conceived the study and, with the other authors, participated in the design, data collection, analysis and interpretation of the results	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation|Methodology	YES
2888781	20482807	OO	2	conceived the study and, with the other authors, participated in the design, data collection, analysis and interpretation of the results	conceived the study and, with the other authors, participated in the design, data collection, analysis and interpretation of the results	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation|Methodology	YES
4383154	25866824	Giuseppe Spaziano	2	contributed equally to the work presented in this paper	contributed equally to the work presented in this paper	-	-	NO
4383154	25866824	Livio Luongo	2	contributed equally to the work presented in this paper	contributed equally to the work presented in this paper	-	-	NO
2890667	20529255	CT	2	drafted and provided critical review of the manuscript	drafted and provided critical review of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
2890667	20529255	EM	2	drafted and provided critical review of the manuscript	drafted and provided critical review of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
2890667	20529255	FHI	2	sponsor of the study had no role in the design, data collection, analysis, interpretation and writing of the report	sponsor of the study had no role in the design, data collection, analysis, interpretation and writing of the report	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology	YES
2890667	20529255	KT	2	conceptualized the paper|drafted and provided critical review of the manuscript	conceptualized the paper	Conceived and designed the experiments	Conceptualization	YES
2890667	20529255	KT	2	conceptualized the paper|drafted and provided critical review of the manuscript	drafted and provided critical review of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
2890667	20529255	LM	2	conceptualized the paper|drafted and provided critical review of the manuscript	conceptualized the paper	Conceived and designed the experiments	Conceptualization	YES
2890667	20529255	LM	2	conceptualized the paper|drafted and provided critical review of the manuscript	drafted and provided critical review of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
2890667	20529255	WvD	2	drafted and provided critical review of the manuscript	drafted and provided critical review of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5456320	28933414	Despina Kyriaki	7	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5456320	28933414	Despina Kyriaki	7	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5456320	28933414	Vaia D. Raikou	7	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5456320	28933414	Vaia D. Raikou	7	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5456320	28933414	Vaia D. Raikou	7	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5456320	28933414	Vaia D. Raikou	7	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5406471	28496452	DD	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5406471	28496452	DL	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5406471	28496452	JZ	PLoS52	analyzed all data	analyzed all data	Analyzed the data	Formal analysis	YES
5406471	28496452	QZ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5406471	28496452	RD	PLoS52	performed the experiments|analyzed all data|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5406471	28496452	RD	PLoS52	performed the experiments|analyzed all data|wrote the manuscript	analyzed all data	Analyzed the data	Formal analysis	YES
5406471	28496452	RD	PLoS52	performed the experiments|analyzed all data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5406471	28496452	WL	PLoS52	analyzed all data	analyzed all data	Analyzed the data	Formal analysis	YES
5406471	28496452	WX	PLoS52	analyzed all data	analyzed all data	Analyzed the data	Formal analysis	YES
5406471	28496452	XC	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5406471	28496452	YD	PLoS52	analyzed all data	analyzed all data	Analyzed the data	Formal analysis	YES
5406471	28496452	YW	PLoS52	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5406471	28496452	ZL	PLoS52	conceived the topic|revised the manuscript	conceived the topic	Conceived and designed the experiments	Conceptualization	YES
5406471	28496452	ZL	PLoS52	conceived the topic|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4383155	25866790	All authors	PLoS52	read and approved the final paper	read and approved the final paper	-	-	NO
4383155	25866790	Byung Jun Ryu	PLoS52	performed the experiments|analyzed and interpreted data|contributed equally to this work	performed the experiments	Performed the experiments	Investigation	YES
4383155	25866790	Byung Jun Ryu	PLoS52	performed the experiments|analyzed and interpreted data|contributed equally to this work	analyzed and interpreted data	Analyzed the data	Formal analysis	YES
4383155	25866790	Byung Jun Ryu	PLoS52	performed the experiments|analyzed and interpreted data|contributed equally to this work	contributed equally to this work	-	-	NO
4383155	25866790	Hye Kyoung Shin	PLoS52	designed and directed the study|performed the experiments|analyzed and interpreted data|wrote the paper|contributed equally to this work	designed and directed the study	Conceived and designed the experiments	Methodology|Supervision	YES
4383155	25866790	Hye Kyoung Shin	PLoS52	designed and directed the study|performed the experiments|analyzed and interpreted data|wrote the paper|contributed equally to this work	performed the experiments	Performed the experiments	Investigation	YES
4383155	25866790	Hye Kyoung Shin	PLoS52	designed and directed the study|performed the experiments|analyzed and interpreted data|wrote the paper|contributed equally to this work	analyzed and interpreted data	Analyzed the data	Formal analysis	YES
4383155	25866790	Hye Kyoung Shin	PLoS52	designed and directed the study|performed the experiments|analyzed and interpreted data|wrote the paper|contributed equally to this work	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4383155	25866790	Hye Kyoung Shin	PLoS52	designed and directed the study|performed the experiments|analyzed and interpreted data|wrote the paper|contributed equally to this work	contributed equally to this work	-	-	NO
4383155	25866790	Kyunglim Lee	PLoS52	designed and directed the study|analyzed and interpreted data|wrote the paper	designed and directed the study	Conceived and designed the experiments	Methodology|Supervision	YES
4383155	25866790	Kyunglim Lee	PLoS52	designed and directed the study|analyzed and interpreted data|wrote the paper	analyzed and interpreted data	Analyzed the data	Formal analysis	YES
4383155	25866790	Kyunglim Lee	PLoS52	designed and directed the study|analyzed and interpreted data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4383155	25866790	Seong Hwan Kim	PLoS52	designed and directed the study|analyzed and interpreted data|wrote the paper	designed and directed the study	Conceived and designed the experiments	Methodology|Supervision	YES
4383155	25866790	Seong Hwan Kim	PLoS52	designed and directed the study|analyzed and interpreted data|wrote the paper	analyzed and interpreted data	Analyzed the data	Formal analysis	YES
4383155	25866790	Seong Hwan Kim	PLoS52	designed and directed the study|analyzed and interpreted data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4383155	25866790	Sik-Won Choi	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
4977642	27507169	AF	7	Polished the whole manuscript	Polished the whole manuscript	Wrote the paper	Writing - Review & Editing	YES
4977642	27507169	BL	7	Conceived and designed the study and wrote the manuscript|Developed the bioinformatics programs and performed the analysis	Conceived and designed the study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
4977642	27507169	BL	7	Conceived and designed the study and wrote the manuscript|Developed the bioinformatics programs and performed the analysis	Developed the bioinformatics programs and performed the analysis	Performed the experiments	Formal analysis|Investigation|Software	YES
4977642	27507169	CZ	7	Developed the bioinformatics programs and performed the analysis	Developed the bioinformatics programs and performed the analysis	Performed the experiments	Formal analysis|Investigation|Software	YES
4977642	27507169	GL	7	Contributed to the analysis and edited the manuscript	Contributed to the analysis and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
4977642	27507169	GW	7	Contributed to the analysis and edited the manuscript	Contributed to the analysis and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
4977642	27507169	HZ	7	implant the framework in dminda webserver	implant the framework in dminda webserver	Contributed reagents/materials/analysis tools	Software	YES
4977642	27507169	QL	7	Contributed to the analysis and edited the manuscript	Contributed to the analysis and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
4977642	27507169	QM	7	Conceived and designed the study and wrote the manuscript|implant the framework in dminda webserver	Conceived and designed the study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
4977642	27507169	QM	7	Conceived and designed the study and wrote the manuscript|implant the framework in dminda webserver	implant the framework in dminda webserver	Contributed reagents/materials/analysis tools	Software	YES
4977642	27507169	YK	7	Contributed to the analysis and edited the manuscript	Contributed to the analysis and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
2890970	20573283	LMR	2	conceived the review, conducted the search for materials and wrote the paper	conceived the review, conducted the search for materials and wrote the paper	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5456321	28933417	K.T.	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5456321	28933417	M.A.	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5456321	28933417	M.N.	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5456321	28933417	O.Y.	PLoS52	contributed reagents/materials/analysis tools|wrote the paper	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5456321	28933417	O.Y.	PLoS52	contributed reagents/materials/analysis tools|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5456321	28933417	R.S.	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5456321	28933417	S.N.	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5456321	28933417	S.W.	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5456321	28933417	S.Y.	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5456321	28933417	T.K.	PLoS52	conceived and designed the experiments|analyzed the data|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5456321	28933417	T.K.	PLoS52	conceived and designed the experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5456321	28933417	T.K.	PLoS52	conceived and designed the experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5456321	28933417	Y.H.	PLoS52	conceived and designed the experiments|analyzed the data|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5456321	28933417	Y.H.	PLoS52	conceived and designed the experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5456321	28933417	Y.H.	PLoS52	conceived and designed the experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
2890971	20573284	EJA	2	helped to conceive the study, and undertook research relevant to production of the manuscript, in addition to editing and revising all parts	helped to conceive the study, and undertook research relevant to production of the manuscript, in addition to editing and revising all parts	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Review & Editing	YES
2890971	20573284	MCSF	2	helped to conceive the study and undertook research relevant to production of the manuscript, and drafted or contributed to all parts	helped to conceive the study and undertook research relevant to production of the manuscript, and drafted or contributed to all parts	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
2890971	20573284	RM	2	screened abstracts and studies for inclusion criteria, drafted the table of selected studies, and assisted in manuscript editing	screened abstracts and studies for inclusion criteria, drafted the table of selected studies, and assisted in manuscript editing	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
2890971	20573284	TSB	2	conceived the study, undertook research relevant to production of the manuscript, facilitated the screening process for study selection, and drafted or contributed to all parts of the manuscript	conceived the study, undertook research relevant to production of the manuscript, facilitated the screening process for study selection, and drafted or contributed to all parts of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
4977653	27501791	KI	2	gave advice on the experiments, data analysis	gave advice on the experiments, data analysis	Analyzed the data	Formal analysis	YES
4977653	27501791	KY	2	conceived the study, drafted and revised the manuscript	conceived the study, drafted and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
4977653	27501791	MI	2	provides machine	provides machine	-	-	NO
4977653	27501791	TK	2	gave advice on the experiments, data analysis	gave advice on the experiments, data analysis	Analyzed the data	Formal analysis	YES
4977653	27501791	TS	2	gave advice on the experiments, data analysis	gave advice on the experiments, data analysis	Analyzed the data	Formal analysis	YES
4977653	27501791	WK	2	carried out all experiments and drafted the manuscript|conceived the study, drafted and revised the manuscript	carried out all experiments and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4977653	27501791	WK	2	carried out all experiments and drafted the manuscript|conceived the study, drafted and revised the manuscript	conceived the study, drafted and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
5406510	28496450	CC	2	performed some of the field work and took part in dna extraction	performed some of the field work and took part in dna extraction	Performed the experiments	Investigation	YES
5406510	28496450	HM	2	constructed the bc 1 population|performed data analysis and linkage mapping	constructed the bc 1 population	Performed the experiments	Investigation	YES
5406510	28496450	HM	2	constructed the bc 1 population|performed data analysis and linkage mapping	performed data analysis and linkage mapping	Analyzed the data	Formal analysis	YES
5406510	28496450	HZ	2	provided valuable research ideas	provided valuable research ideas	Conceived and designed the experiments	Conceptualization	YES
5406510	28496450	KW	2	performed some of the field work and took part in dna extraction	performed some of the field work and took part in dna extraction	Performed the experiments	Investigation	YES
5406510	28496450	XJ	2	performed some of the field work and took part in dna extraction	performed some of the field work and took part in dna extraction	Performed the experiments	Investigation	YES
5406510	28496450	YL	2	performed data analysis and linkage mapping|revised the manuscript	performed data analysis and linkage mapping	Analyzed the data	Formal analysis	YES
5406510	28496450	YL	2	performed data analysis and linkage mapping|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5406510	28496450	YZ	2	designed and supervised the study	designed and supervised the study	Conceived and designed the experiments	Methodology|Supervision	YES
5406510	28496450	ZD	2	constructed the bc 1 population	constructed the bc 1 population	Performed the experiments	Investigation	YES
2890972	20573285	BTM	2	were responsible for critical revision of the manuscript for important intellectual content	were responsible for critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
2890972	20573285	JFF	2	were responsible for critical revision of the manuscript for important intellectual content	were responsible for critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
2890972	20573285	SCL	2	undertook the study concept and design, and analysis and interpretation of data	undertook the study concept and design, and analysis and interpretation of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation|Methodology	YES
2890972	20573285	TPF	2	were responsible for critical revision of the manuscript for important intellectual content	were responsible for critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4977659	27502271	KJ	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4977659	27502271	LM	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4977659	27502271	WS	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
2890973	20573286	N. Barry	3	Assistance in the empirical study	Assistance in the empirical study	-	-	NO
2890973	20573286	N. Jahn	3	Assistance in gathering references for the systematic review is acknowledged	Assistance in gathering references for the systematic review is acknowledged	-	-	NO
5456323	28933416	B.C.I.	2	they facilitated the writing of the methods and discussion of the manuscripts	they facilitated the writing of the methods and discussion of the manuscripts	Performed the experiments|Wrote the paper	Writing - Original Draft	YES
5456323	28933416	F.Z.	2	wrote the results, conclusion and assisted a	wrote the results, conclusion and assisted a	Wrote the paper	Writing - Original Draft	YES
5406782	28496454	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5406782	28496454	GR	PLoS52	designed the experiments|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5406782	28496454	GR	PLoS52	designed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5406782	28496454	JH	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5406782	28496454	JH	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5406782	28496454	SB	PLoS52	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5406782	28496454	XL	PLoS52	designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5406782	28496454	XL	PLoS52	designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5406782	28496454	XL	PLoS52	designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5406782	28496454	XL	PLoS52	designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5406782	28496454	YF	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
2890974	20573287	SM	2	drafted the manuscript and approved the final version	drafted the manuscript and approved the final version	Wrote the paper	Writing - Original Draft	YES
2890974	20573287	VH	2	drafted the manuscript and approved the final version	drafted the manuscript and approved the final version	Wrote the paper	Writing - Original Draft	YES
4977665	27503539	AP	2	assisted in drafting of the manuscript	assisted in drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
4977665	27503539	Acala Maxxa	2	and ga120r1b3	and ga120r1b3	-	-	NO
4977665	27503539	BN	2	assisted in drafting of the manuscript	assisted in drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
4977665	27503539	DP	2	assisted in drafting of the manuscript	assisted in drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
4977665	27503539	PC	2	assisted in drafting of the manuscript	assisted in drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
4977665	27503539	PK	2	developed the interspecific f2 population and performed the ssr genotyping work	developed the interspecific f2 population and performed the ssr genotyping work	Performed the experiments	Investigation	YES
4977665	27503539	RD	2	performed the phenotypic evaluations	performed the phenotypic evaluations	Performed the experiments	Investigation	YES
4977665	27503539	RS	2	developed the interspecific f2 population and performed the ssr genotyping work	developed the interspecific f2 population and performed the ssr genotyping work	Performed the experiments	Investigation	YES
4977665	27503539	XS	2	developed the interspecific f2 population and performed the ssr genotyping work	developed the interspecific f2 population and performed the ssr genotyping work	Performed the experiments	Investigation	YES
4977665	27503539	YH	2	developed the interspecific f2 population and performed the ssr genotyping work	developed the interspecific f2 population and performed the ssr genotyping work	Performed the experiments	Investigation	YES
2890975	20573288	DF	2	designed the literature search protocol, carried out research, and contributed to the written content	designed the literature search protocol, carried out research, and contributed to the written content	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
2890975	20573288	GB	2	designed the literature search protocol, carried out research, and drafted and revised the manuscript	designed the literature search protocol, carried out research, and drafted and revised the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
2890975	20573288	JB	2	designed the literature search protocol, carried out research, and drafted and revised the manuscript	designed the literature search protocol, carried out research, and drafted and revised the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
2890975	20573288	JC	2	participated in drafting and revising the manuscript	participated in drafting and revising the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
2890975	20573288	JLS	2	participated in drafting and revising the manuscript	participated in drafting and revising the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
2890975	20573288	MB	2	designed the literature search protocol, carried out research, and contributed to the written content	designed the literature search protocol, carried out research, and contributed to the written content	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
2890975	20573288	MIB	2	designed the literature search protocol, carried out research, and contributed to the written content	designed the literature search protocol, carried out research, and contributed to the written content	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
2890975	20573288	MO	2	designed the literature search protocol, carried out research, and contributed to the written content	designed the literature search protocol, carried out research, and contributed to the written content	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5407058	28496453	AM	2	performed and elaborated rna seq data	performed and elaborated rna seq data	Performed the experiments	Investigation	YES
5407058	28496453	CA	2	performed and elaborated rna seq data	performed and elaborated rna seq data	Performed the experiments	Investigation	YES
5407058	28496453	DS	2	elaborated agronomical data	elaborated agronomical data	-	-	NO
5407058	28496453	FM	2	critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5407058	28496453	GGa	2	designed the experiments, contributed to data analysis and to the writing	designed the experiments, contributed to data analysis and to the writing	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology	YES
5407058	28496453	GGi	2	performed the pathogenicity test	performed the pathogenicity test	Performed the experiments	Investigation	YES
5407058	28496453	IP	2	performed most of the molecular analysis, analyzed the data and wrote the manuscript	performed most of the molecular analysis, analyzed the data and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5407058	28496453	MD	2	critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5407058	28496453	MG	2	critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5407058	28496453	PB	2	collaborated to the molecular analysis	collaborated to the molecular analysis	Performed the experiments	Investigation	YES
5407058	28496453	WC	2	performed most of the molecular analysis, analyzed the data and wrote the manuscript	performed most of the molecular analysis, analyzed the data and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5407058	28496453	all authors	2	read and approved the manuscript	read and approved the manuscript	-	-	NO
2890976	20573289	AKS	2	oversaw the collection of the data	oversaw the collection of the data	Performed the experiments	Investigation|Supervision	YES
2890976	20573289	All authors	2	assisted in drafting the manuscript, and read and approved the final manuscript	assisted in drafting the manuscript, and read and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
2890976	20573289	DDC	2	conceived these studies, designed the data collection methods and interpreted the data	conceived these studies, designed the data collection methods and interpreted the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation|Methodology	YES
2890976	20573289	SHM	2	conceived these studies, designed the data collection methods and interpreted the data|conducted the data analysis	conceived these studies, designed the data collection methods and interpreted the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation|Methodology	YES
2890976	20573289	SHM	2	conceived these studies, designed the data collection methods and interpreted the data|conducted the data analysis	conducted the data analysis	Analyzed the data	Formal analysis	YES
2890976	20573289	SSS	2	conceived these studies, designed the data collection methods and interpreted the data|oversaw the collection of the data|conducted the data analysis	conceived these studies, designed the data collection methods and interpreted the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation|Methodology	YES
2890976	20573289	SSS	2	conceived these studies, designed the data collection methods and interpreted the data|oversaw the collection of the data|conducted the data analysis	oversaw the collection of the data	Performed the experiments	Investigation|Supervision	YES
2890976	20573289	SSS	2	conceived these studies, designed the data collection methods and interpreted the data|oversaw the collection of the data|conducted the data analysis	conducted the data analysis	Analyzed the data	Formal analysis	YES
4977670	27503086	FYP	2	carried out bioinformatics analysis and prepared the first draft of the manuscript	carried out bioinformatics analysis and prepared the first draft of the manuscript	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4977670	27503086	R-CY	2	conceived the project, supervised the analysis and revised the manuscript	conceived the project, supervised the analysis and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Supervision|Writing - Review & Editing	YES
4977670	27503086	ZQH	2	performed pwm filtering and statistical analysis	performed pwm filtering and statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5408010	28503178	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5408010	28503178	DL	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5408010	28503178	DM	PLoS52	analyzed the data|wrote and revised the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5408010	28503178	DM	PLoS52	analyzed the data|wrote and revised the paper	wrote and revised the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5408010	28503178	HL	PLoS52	conceived and designed the experiments|contributed reagents and materials	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5408010	28503178	HL	PLoS52	conceived and designed the experiments|contributed reagents and materials	contributed reagents and materials	Contributed reagents/materials/analysis tools	Resources	YES
5408010	28503178	HY	PLoS52	conceived and designed the experiments|contributed reagents and materials	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5408010	28503178	HY	PLoS52	conceived and designed the experiments|contributed reagents and materials	contributed reagents and materials	Contributed reagents/materials/analysis tools	Resources	YES
5408010	28503178	JH	PLoS52	wrote and revised the paper	wrote and revised the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5408010	28503178	LM	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5408010	28503178	LM	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5408010	28503178	XH	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5408010	28503178	XL	PLoS52	conceived and designed the experiments|contributed reagents and materials	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5408010	28503178	XL	PLoS52	conceived and designed the experiments|contributed reagents and materials	contributed reagents and materials	Contributed reagents/materials/analysis tools	Resources	YES
5408010	28503178	XY	PLoS52	conceived and designed the experiments|performed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5408010	28503178	XY	PLoS52	conceived and designed the experiments|performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5408010	28503178	YL	PLoS52	conceived and designed the experiments|contributed reagents and materials	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5408010	28503178	YL	PLoS52	conceived and designed the experiments|contributed reagents and materials	contributed reagents and materials	Contributed reagents/materials/analysis tools	Resources	YES
2890977	20573290	All authors	2	are responsible for the gathering and interpretation of the material, the compilation of the paper, and the decision to submit the paper for publication	are responsible for the gathering and interpretation of the material, the compilation of the paper, and the decision to submit the paper for publication	Analyzed the data	Formal analysis	YES
5456325	28933418	Jimenez Jimenez	2	conducted the review of the entire article	conducted the review of the entire article	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5456325	28933418	The three authors	2	carried out the literature search and completed the written paper	carried out the literature search and completed the written paper	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4977689	27501838	D-HJ	2	provided and analyzed pare data	provided and analyzed pare data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
4977689	27501838	HJ	2	performed the molecular experiments and stress tests|wrote the manuscripts	performed the molecular experiments and stress tests	Performed the experiments	Investigation	YES
4977689	27501838	HJ	2	performed the molecular experiments and stress tests|wrote the manuscripts	wrote the manuscripts	Wrote the paper	Writing - Original Draft	YES
4977689	27501838	J-KK	2	designed the research|wrote the manuscripts	designed the research	Conceived and designed the experiments	Methodology	YES
4977689	27501838	J-KK	2	designed the research|wrote the manuscripts	wrote the manuscripts	Wrote the paper	Writing - Original Draft	YES
4977689	27501838	PJC	2	designed the research|performed the molecular experiments and stress tests|analyses rna seq|wrote the manuscripts	designed the research	Conceived and designed the experiments	Methodology	YES
4977689	27501838	PJC	2	designed the research|performed the molecular experiments and stress tests|analyses rna seq|wrote the manuscripts	performed the molecular experiments and stress tests	Performed the experiments	Investigation	YES
4977689	27501838	PJC	2	designed the research|performed the molecular experiments and stress tests|analyses rna seq|wrote the manuscripts	analyses rna seq	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4977689	27501838	PJC	2	designed the research|performed the molecular experiments and stress tests|analyses rna seq|wrote the manuscripts	wrote the manuscripts	Wrote the paper	Writing - Original Draft	YES
4977689	27501838	S-HH	2	wrote the manuscripts	wrote the manuscripts	Wrote the paper	Writing - Original Draft	YES
4977689	27501838	YDC	2	wrote the manuscripts	wrote the manuscripts	Wrote the paper	Writing - Original Draft	YES
2890978	20573291	MT	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
2890978	20573291	The author	2	has approved the final manuscript	has approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5408072	28503183	All authors	2	carried out experiments and assisted with writing the manuscript	carried out experiments and assisted with writing the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4977694	27502506	AW	2	did the cellular assays	did the cellular assays	Performed the experiments	Investigation	YES
4977694	27502506	CK	2	conceived the study, and participated in its design and coordination, performed the patient data analyses, and helped to draft the manuscript	conceived the study, and participated in its design and coordination, performed the patient data analyses, and helped to draft the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Project administration|Writing - Original Draft	YES
4977694	27502506	EM	2	cloned and mutated the luciferase reporter constructs	cloned and mutated the luciferase reporter constructs	Performed the experiments	Investigation	YES
4977694	27502506	HW	2	did the cellular assays	did the cellular assays	Performed the experiments	Investigation	YES
4977694	27502506	JJ	2	did the cellular assays	did the cellular assays	Performed the experiments	Investigation	YES
4977694	27502506	NE	2	did the cellular assays	did the cellular assays	Performed the experiments	Investigation	YES
4977694	27502506	OS	2	did the cellular assays, all statistical analyses, and drafted the manuscript	did the cellular assays, all statistical analyses, and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4977694	27502506	SW	2	participated in the design of the study and helped to draft the manuscript	participated in the design of the study and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5456326	28933411	D.C.	PLoS52	conceived and designed the review	conceived and designed the review	Conceived and designed the experiments	Conceptualization	YES
5456326	28933411	G.T.	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5456326	28933411	I.d.L.	PLoS52	conceived and designed the review	conceived and designed the review	Conceived and designed the experiments	Conceptualization	YES
5456326	28933411	J.M.S.-R.	PLoS52	contributed by searching references	contributed by searching references	-	-	NO
5456326	28933411	M.A.-C.	PLoS52	contributed by searching references	contributed by searching references	-	-	NO
5456326	28933411	M.O.-A.	PLoS52	contributed by searching references	contributed by searching references	-	-	NO
5456326	28933411	M.V.-P.	PLoS52	conceived and designed the review	conceived and designed the review	Conceived and designed the experiments	Conceptualization	YES
5456326	28933411	M.d.l.M.	PLoS52	conceived and designed the review|wrote the paper	conceived and designed the review	Conceived and designed the experiments	Conceptualization	YES
5456326	28933411	M.d.l.M.	PLoS52	conceived and designed the review|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5456326	28933411	R.L.-H.	PLoS52	contributed by searching references	contributed by searching references	-	-	NO
2894007	20525230	CMN	2	participated in design and implementation of the study	participated in design and implementation of the study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
2894007	20525230	GN	2	participated in the conception, design and implementation of the study, statistical analysis, interpretation and drafting of the manuscript	participated in the conception, design and implementation of the study, statistical analysis, interpretation and drafting of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
2894007	20525230	JKT	2	participated in the conception, design and implementation of the study, statistical analysis, interpretation and drafting of the manuscript	participated in the conception, design and implementation of the study, statistical analysis, interpretation and drafting of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
2894007	20525230	TT	2	participated in the conception, design and implementation of the study, statistical analysis, interpretation and drafting of the manuscript	participated in the conception, design and implementation of the study, statistical analysis, interpretation and drafting of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
2895577	20540795	AK	2	assisted with data analysis	assisted with data analysis	Analyzed the data	Formal analysis	YES
2895577	20540795	GS	2	were involved in the development of the study concept	were involved in the development of the study concept	Conceived and designed the experiments	Conceptualization	YES
2895577	20540795	HD	2	were involved in the development of the study concept|worked on study design|performed data collection	were involved in the development of the study concept	Conceived and designed the experiments	Conceptualization	YES
2895577	20540795	HD	2	were involved in the development of the study concept|worked on study design|performed data collection	worked on study design	Conceived and designed the experiments|Performed the experiments	Methodology	YES
2895577	20540795	HD	2	were involved in the development of the study concept|worked on study design|performed data collection	performed data collection	Performed the experiments	Investigation	YES
2895577	20540795	L. All	2	authors reviewed and agree with the findings in the final manuscript	authors reviewed and agree with the findings in the final manuscript	Wrote the paper	Writing - Review & Editing	YES
2895577	20540795	RL	2	were involved in the development of the study concept|worked on study design|assisted with data analysis	were involved in the development of the study concept	Conceived and designed the experiments	Conceptualization	YES
2895577	20540795	RL	2	were involved in the development of the study concept|worked on study design|assisted with data analysis	worked on study design	Conceived and designed the experiments|Performed the experiments	Methodology	YES
2895577	20540795	RL	2	were involved in the development of the study concept|worked on study design|assisted with data analysis	assisted with data analysis	Analyzed the data	Formal analysis	YES
2895577	20540795	TC	2	were involved in the development of the study concept|worked on study design	were involved in the development of the study concept	Conceived and designed the experiments	Conceptualization	YES
2895577	20540795	TC	2	were involved in the development of the study concept|worked on study design	worked on study design	Conceived and designed the experiments|Performed the experiments	Methodology	YES
5408081	28503179	DX	7	conceived the research work|prepared the figures and tables|wrote the paper	conceived the research work	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5408081	28503179	DX	7	conceived the research work|prepared the figures and tables|wrote the paper	prepared the figures and tables	-	Visualization	YES
5408081	28503179	DX	7	conceived the research work|prepared the figures and tables|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5408081	28503179	GC	7	conducted bioinformatics analysis|prepared the figures and tables	conducted bioinformatics analysis	Performed the experiments	Formal analysis|Investigation	YES
5408081	28503179	GC	7	conducted bioinformatics analysis|prepared the figures and tables	prepared the figures and tables	-	Visualization	YES
5408081	28503179	XL	7	conducted bioinformatics analysis|prepared the figures and tables	conducted bioinformatics analysis	Performed the experiments	Formal analysis|Investigation	YES
5408081	28503179	XL	7	conducted bioinformatics analysis|prepared the figures and tables	prepared the figures and tables	-	Visualization	YES
5408081	28503179	XZ	7	prepared the figures and tables	prepared the figures and tables	-	Visualization	YES
5408081	28503179	Z-HC	7	conceived the research work|prepared the figures and tables|wrote the paper	conceived the research work	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5408081	28503179	Z-HC	7	conceived the research work|prepared the figures and tables|wrote the paper	prepared the figures and tables	-	Visualization	YES
5408081	28503179	Z-HC	7	conceived the research work|prepared the figures and tables|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4977696	27502607	B.A.G.	2	analyzed and annotated the genome	analyzed and annotated the genome	Analyzed the data	Formal analysis	YES
4977696	27502607	KGH	2	performed the pcr-experiments and worked on the manuscript	performed the pcr-experiments and worked on the manuscript	Performed the experiments	Investigation	YES
4977696	27502607	S.G.	2	analyzed and annotated the genome	analyzed and annotated the genome	Analyzed the data	Formal analysis	YES
4977696	27502607	WH	2	conceived and supervised the study and drafted the manuscript	conceived and supervised the study and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Supervision|Writing - Original Draft	YES
5456327	28933415	All authors	2	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5456327	28933415	H.H.	2	performed curation of the data|led the research	performed curation of the data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5456327	28933415	H.H.	2	performed curation of the data|led the research	led the research	-	-	NO
5456327	28933415	M.F.	2	performed data mining, extraction and analysis of the fabry datasets|performed curation of the data	performed data mining, extraction and analysis of the fabry datasets	Analyzed the data	Data curation|Formal analysis	YES
5456327	28933415	M.F.	2	performed data mining, extraction and analysis of the fabry datasets|performed curation of the data	performed curation of the data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5456327	28933415	all authors	2	led the research	led the research	-	-	NO
2896341	20540714	BM	2	contributed equally to the conception, design and implementation of the study	contributed equally to the conception, design and implementation of the study	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
2896341	20540714	NM	2	contributed equally to the conception, design and implementation of the study	contributed equally to the conception, design and implementation of the study	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
4383273	25866762	Daniel Gomes Ferrari	1	And the following authors were responsible for the numerical analyses of the data	And the following authors were responsible for the numerical analyses of the data	Analyzed the data	Formal analysis	YES
4383273	25866762	Enrique Redondo Gonzalez	1	The following authors were responsible for the biological part and analyses of the paper	The following authors were responsible for the biological part and analyses of the paper	Analyzed the data	Formal analysis	YES
4383273	25866762	Jesus Moreno Sierra	1	The following authors were responsible for the biological part and analyses of the paper	The following authors were responsible for the biological part and analyses of the paper	Analyzed the data	Formal analysis	YES
4383273	25866762	Las Casas	1	The following authors were responsible for the biological part and analyses of the paper	The following authors were responsible for the biological part and analyses of the paper	Analyzed the data	Formal analysis	YES
4383273	25866762	Leandro Nunes	1	And the following authors were responsible for the numerical analyses of the data	And the following authors were responsible for the numerical analyses of the data	Analyzed the data	Formal analysis	YES
4383273	25866762	Maria Luisa Maestro	1	The following authors were responsible for the biological part and analyses of the paper	The following authors were responsible for the biological part and analyses of the paper	Analyzed the data	Formal analysis	YES
5408084	28503185	EH	2	designed the study and prepared the manuscript	designed the study and prepared the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5408084	28503185	GF	2	proposed the research, designed the study, and prepared the manuscript	proposed the research, designed the study, and prepared the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
5408084	28503185	TK	2	designed the study and prepared the manuscript	designed the study and prepared the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5408084	28503185	X-XW	2	designed the study, harvested samples, collected the data, analyzed the data, wrote the first draft, and prepared the manuscript	designed the study, harvested samples, collected the data, analyzed the data, wrote the first draft, and prepared the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
2901349	20546580	OA	2	was responsible for conceptualizing and designing this study|was also responsible for conducting, analyzing, and writing up of drafts and the final version of the manuscript	was responsible for conceptualizing and designing this study	Conceived and designed the experiments	Conceptualization|Methodology	YES
2901349	20546580	OA	2	was responsible for conceptualizing and designing this study|was also responsible for conducting, analyzing, and writing up of drafts and the final version of the manuscript	was also responsible for conducting, analyzing, and writing up of drafts and the final version of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4977709	27502941	ACL	2	conceived and supervised the study and participated in manuscript writing	conceived and supervised the study and participated in manuscript writing	Conceived and designed the experiments|Wrote the paper	Conceptualization|Supervision|Writing - Original Draft	YES
4977709	27502941	EP	2	conceived and supervised the study and participated in manuscript writing	conceived and supervised the study and participated in manuscript writing	Conceived and designed the experiments|Wrote the paper	Conceptualization|Supervision|Writing - Original Draft	YES
4977709	27502941	HL	2	performed chromatin immunoprecipitation, in vitro dna binding and gene expression experiments, performed bioinformatic and data analyses and participated in manuscript writing	performed chromatin immunoprecipitation, in vitro dna binding and gene expression experiments, performed bioinformatic and data analyses and participated in manuscript writing	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4977709	27502941	KW	2	performed bioinformatic and data analysis and participated in manuscript writing	performed bioinformatic and data analysis and participated in manuscript writing	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5456329	28933413	C.C.S.	2	also did extensive literature review, wrote some of the manuscript and corrected mistakes in the first draft	also did extensive literature review, wrote some of the manuscript and corrected mistakes in the first draft	Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5456329	28933413	K.H.	2	also did extensive literature review, wrote some of the manuscript and corrected mistakes in the first draft	also did extensive literature review, wrote some of the manuscript and corrected mistakes in the first draft	Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5456329	28933413	K.T.	2	also did extensive literature review, wrote some of the manuscript and corrected mistakes in the first draft	also did extensive literature review, wrote some of the manuscript and corrected mistakes in the first draft	Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5456329	28933413	M.M.	2	also did extensive literature review, wrote some of the manuscript and corrected mistakes in the first draft	also did extensive literature review, wrote some of the manuscript and corrected mistakes in the first draft	Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5456329	28933413	P.S.	2	also did extensive literature review, wrote some of the manuscript and corrected mistakes in the first draft	also did extensive literature review, wrote some of the manuscript and corrected mistakes in the first draft	Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5456329	28933413	R.E.S.	2	did some of the literature review and wrote most of the manuscript	did some of the literature review and wrote most of the manuscript	Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
2912249	20626901	DA	2	carried out the immunological studies	carried out the immunological studies	Performed the experiments	Investigation	YES
2912249	20626901	JEL	2	participated in the statistical analysis and drafting of the manuscript	participated in the statistical analysis and drafting of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
2912249	20626901	MJM	2	conceived the study, participated in its design and coordination, and drafting of the manuscript	conceived the study, participated in its design and coordination, and drafting of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
2912249	20626901	NM	2	carried out the immunological studies	carried out the immunological studies	Performed the experiments	Investigation	YES
2912249	20626901	RD	2	participated in the statistical analysis and drafting of the manuscript	participated in the statistical analysis and drafting of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
2912249	20626901	RMM	2	participated in the drafting of the manuscript	participated in the drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
2912249	20626901	RR	2	participated in the drafting of the manuscript	participated in the drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
2912249	20626901	VEB	2	participated in the drafting of the manuscript	participated in the drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
2912249	20626901	XB	2	participated in the formatting of the manuscript and prepared the references used for the article	participated in the formatting of the manuscript and prepared the references used for the article	Wrote the paper	Writing - Original Draft	YES
5408085	28503186	CWL	2	performed experiments and analyzed the results	performed experiments and analyzed the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5408085	28503186	HJ	2	performed experiments and analyzed the results	performed experiments and analyzed the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5408085	28503186	S-WH	2	designed the experiments and wrote the manuscript	designed the experiments and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5408085	28503186	SCL	2	designed the experiments and wrote the manuscript	designed the experiments and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
2914050	20624303	BH	2	wrote, reviewed, and edited the manuscript	wrote, reviewed, and edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
2914050	20624303	CD	2	wrote, reviewed, and edited the manuscript	wrote, reviewed, and edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
2914050	20624303	CH	2	wrote, reviewed, and edited the manuscript	wrote, reviewed, and edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
2914050	20624303	JM	2	wrote, reviewed, and edited the manuscript	wrote, reviewed, and edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
2914050	20624303	JR	2	wrote, reviewed, and edited the manuscript	wrote, reviewed, and edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
2914050	20624303	KOR	2	wrote, reviewed, and edited the manuscript	wrote, reviewed, and edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
2914050	20624303	LP	2	wrote, reviewed, and edited the manuscript	wrote, reviewed, and edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
2914050	20624303	MD	2	wrote, reviewed, and edited the manuscript	wrote, reviewed, and edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
2914050	20624303	MW	2	wrote, reviewed, and edited the manuscript	wrote, reviewed, and edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
2914050	20624303	PP	2	wrote, reviewed, and edited the manuscript	wrote, reviewed, and edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
2914050	20624303	SB	2	wrote, reviewed, and edited the manuscript	wrote, reviewed, and edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
2914050	20624303	SK	2	wrote, reviewed, and edited the manuscript	wrote, reviewed, and edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
2914050	20624303	YRL	2	wrote, reviewed, and edited the manuscript	wrote, reviewed, and edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4977732	27501690	AC	2	created and maintained the mapping population|coordinated and organized all research activities	created and maintained the mapping population	-	-	NO
4977732	27501690	AC	2	created and maintained the mapping population|coordinated and organized all research activities	coordinated and organized all research activities	-	Project administration	YES
4977732	27501690	ADG	2	created and maintained the mapping population	created and maintained the mapping population	-	-	NO
4977732	27501690	FAW	2	comparative genomics analysis	comparative genomics analysis	Performed the experiments	Investigation	YES
4977732	27501690	FW	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4977732	27501690	JAR	2	conducted in vitro insect feeding bioassays	conducted in vitro insect feeding bioassays	Performed the experiments	Investigation	YES
4977732	27501690	MCE	2	created and maintained the mapping population	created and maintained the mapping population	-	-	NO
4977732	27501690	QY	2	wrote the manuscript|coordinated and organized all research activities	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4977732	27501690	QY	2	wrote the manuscript|coordinated and organized all research activities	coordinated and organized all research activities	-	Project administration	YES
4977732	27501690	RS	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4977732	27501690	XH	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4383278	25866759	Eleonora Rolli	2	contributed equally to the work	contributed equally to the work	-	-	NO
4383278	25866759	Ramona Marasco	2	contributed equally to the work	contributed equally to the work	-	-	NO
4383278	25866759	Raoudha Ferjani	2	contributed equally to the work	contributed equally to the work	-	-	NO
5408224	28503181	LT	2	wrote the manuscript|analyzed the experiments data	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5408224	28503181	LT	2	wrote the manuscript|analyzed the experiments data	analyzed the experiments data	Analyzed the data	Formal analysis	YES
5408224	28503181	QC	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5408224	28503181	SA	2	analyzed the experiments data|provided advice and edited the manuscript	analyzed the experiments data	Analyzed the data	Formal analysis	YES
5408224	28503181	SA	2	analyzed the experiments data|provided advice and edited the manuscript	provided advice and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5408224	28503181	WC	2	provided advice and edited the manuscript	provided advice and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5408224	28503181	XL	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5408224	28503181	XQ	2	provided advice and edited the manuscript|performed experiments	provided advice and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5408224	28503181	XQ	2	provided advice and edited the manuscript|performed experiments	performed experiments	Performed the experiments	Investigation	YES
5408224	28503181	YL	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5408224	28503181	YZ	2	provided advice and edited the manuscript	provided advice and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5408224	28503181	ZH	2	wrote the manuscript|analyzed the experiments data|performed experiments	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5408224	28503181	ZH	2	wrote the manuscript|analyzed the experiments data|performed experiments	analyzed the experiments data	Analyzed the data	Formal analysis	YES
5408224	28503181	ZH	2	wrote the manuscript|analyzed the experiments data|performed experiments	performed experiments	Performed the experiments	Investigation	YES
5456330	28933412	Juliana Ines Santos	2	participated in the selection, organization, and summary of selected data, and figure design	participated in the selection, organization, and summary of selected data, and figure design	Conceived and designed the experiments	Visualization	YES
5456330	28933412	Liliana Matos	2	participated in the organization of selected data	participated in the organization of selected data	-	-	NO
5456330	28933412	Maria Francisca Coutinho	2	conceived the idea and designed the paper and was responsible for the selection, organization, and summary of the published literature to which reference is made in this review	conceived the idea and designed the paper and was responsible for the selection, organization, and summary of the published literature to which reference is made in this review	Conceived and designed the experiments	Conceptualization|Formal analysis	YES
5456330	28933412	Sandra Alves	2	conceived the idea and revised the paper	conceived the idea and revised the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
2914751	20615222	AB	2	contributed to the data collection or analysis|contributed to the concept, intellectual content and writing of the paper	contributed to the data collection or analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
2914751	20615222	AB	2	contributed to the data collection or analysis|contributed to the concept, intellectual content and writing of the paper	contributed to the concept, intellectual content and writing of the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
2914751	20615222	GM	2	wrote the first draft of the study protocol|contributed to the data collection or analysis	wrote the first draft of the study protocol	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
2914751	20615222	GM	2	wrote the first draft of the study protocol|contributed to the data collection or analysis	contributed to the data collection or analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
2914751	20615222	GVC	2	wrote the first draft of the study protocol|contributed to the data collection or analysis|contributed to the concept, intellectual content and writing of the paper	wrote the first draft of the study protocol	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
2914751	20615222	GVC	2	wrote the first draft of the study protocol|contributed to the data collection or analysis|contributed to the concept, intellectual content and writing of the paper	contributed to the data collection or analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
2914751	20615222	GVC	2	wrote the first draft of the study protocol|contributed to the data collection or analysis|contributed to the concept, intellectual content and writing of the paper	contributed to the concept, intellectual content and writing of the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
2914751	20615222	KC	2	was responsible for the overall design, analysis and writing of the paper	was responsible for the overall design, analysis and writing of the paper	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
2914751	20615222	NF	2	contributed to the concept, intellectual content and writing of the paper	contributed to the concept, intellectual content and writing of the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
2914751	20615222	SS	2	contributed to the data collection or analysis	contributed to the data collection or analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4977763	27503363	All authors	2	gave the final approval for the final version of this manuscript	gave the final approval for the final version of this manuscript	-	-	NO
4977763	27503363	CEA	2	participated in the design of the experiments, provided interpretation to results and drafted the manuscript	participated in the design of the experiments, provided interpretation to results and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4977763	27503363	IZ	2	participated in the design of the experiments, carried out the analyzes, provided interpretation to results and drafted the manuscript	participated in the design of the experiments, carried out the analyzes, provided interpretation to results and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4977763	27503363	JAS	2	obtained additional data and drafted the manuscript	obtained additional data and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
2918569	20642843	AS	2	critically reviewed the study protocol, and screened and extracted data from peer-reviewed articles	critically reviewed the study protocol, and screened and extracted data from peer-reviewed articles	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
2918569	20642843	All authors	2	assisted with analysis and interpretation of the data, reviewed the manuscript for important intellectual content, and provided final approval of the version submitted for publication	assisted with analysis and interpretation of the data, reviewed the manuscript for important intellectual content, and provided final approval of the version submitted for publication	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
2918569	20642843	CK	2	served as lead study coordinator and coordinator for peer-reviewed studies, co-led design of the study protocol, conducted online database searches, screened and extracted data from peer-reviewed articles, and drafted the manuscript	served as lead study coordinator and coordinator for peer-reviewed studies, co-led design of the study protocol, conducted online database searches, screened and extracted data from peer-reviewed articles, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Data curation|Investigation|Methodology|Project administration|Software|Writing - Original Draft|Writing - Review & Editing	YES
2918569	20642843	DBB	2	screened and extracted data from promising practices	screened and extracted data from promising practices	Performed the experiments	Investigation	YES
2918569	20642843	GK	2	served as overall project coordinator, assisted with design of the study protocol, and screened and extracted data from promising practices	served as overall project coordinator, assisted with design of the study protocol, and screened and extracted data from promising practices	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Project administration	YES
2918569	20642843	JM	2	screened and extracted data from promising practices	screened and extracted data from promising practices	Performed the experiments	Investigation	YES
2918569	20642843	KO	2	conceptualized the study, and critically reviewed the study protocol	conceptualized the study, and critically reviewed the study protocol	Conceived and designed the experiments	Conceptualization|Methodology	YES
2918569	20642843	LA	2	served as coordinator for promising practices, and screened and extracted data from promising practices	served as coordinator for promising practices, and screened and extracted data from promising practices	Performed the experiments	Investigation|Project administration	YES
2918569	20642843	LC	2	conceptualized the study, and critically reviewed the study protocol	conceptualized the study, and critically reviewed the study protocol	Conceived and designed the experiments	Conceptualization|Methodology	YES
2918569	20642843	LP	2	co-led design of the study protocol, and screened promising practices	co-led design of the study protocol, and screened promising practices	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
2918569	20642843	MM	2	conceptualized the study, and critically reviewed the study protocol	conceptualized the study, and critically reviewed the study protocol	Conceived and designed the experiments	Conceptualization|Methodology	YES
5408325	28503180	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5408325	28503180	HX	2	conceived of the study and prepared the manuscript	conceived of the study and prepared the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5408325	28503180	JZ	2	offer the help of as cloning, vector construction, protein expression and gc-ms detection	offer the help of as cloning, vector construction, protein expression and gc-ms detection	Performed the experiments	Investigation	YES
5408325	28503180	LW	2	contributed to the tissue samples collection, rna extraction, data analysis and writing of this manuscript	contributed to the tissue samples collection, rna extraction, data analysis and writing of this manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft	YES
5408325	28503180	RZ	2	dedicated the identification of origin plant	dedicated the identification of origin plant	Performed the experiments	Investigation	YES
5408325	28503180	The authors	2	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	Performed the experiments	Investigation	YES
5408325	28503180	WC	2	participated in designing the study and coordination	participated in designing the study and coordination	Conceived and designed the experiments	Methodology|Project administration	YES
5408325	28503180	XY	2	offer the help of as cloning, vector construction, protein expression and gc-ms detection	offer the help of as cloning, vector construction, protein expression and gc-ms detection	Performed the experiments	Investigation	YES
5408325	28503180	XZ	2	contributed to establishment of yeast expression system, determination of amyrin by gc-ms and helped to draft the manuscript	contributed to establishment of yeast expression system, determination of amyrin by gc-ms and helped to draft the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5408325	28503180	YC	2	offer the help of as cloning, vector construction, protein expression and gc-ms detection	offer the help of as cloning, vector construction, protein expression and gc-ms detection	Performed the experiments	Investigation	YES
5408325	28503180	YX	2	offer the help of as cloning, vector construction, protein expression and gc-ms detection	offer the help of as cloning, vector construction, protein expression and gc-ms detection	Performed the experiments	Investigation	YES
2919446	20649967	EH	2	participated in the interpretation of data	participated in the interpretation of data	Analyzed the data	Formal analysis	YES
2919446	20649967	FAa	2	participated in the design of the study and interpretation of data	participated in the design of the study and interpretation of data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
2919446	20649967	FAm	2	participated in the design of the study and interpretation of data	participated in the design of the study and interpretation of data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
2919446	20649967	FR	2	conceived the study and participated in the design, data collection and analysis	conceived the study and participated in the design, data collection and analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation|Methodology	YES
2919446	20649967	MB	2	participated in the design of the study and preparation of the manuscript	participated in the design of the study and preparation of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
2919446	20649967	SN	2	conceived the study, took part in coordination and helped to draft the manuscript	conceived the study, took part in coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Project administration|Writing - Original Draft	YES
2919446	20649967	SST	2	participated in the design of the study and interpretation of data	participated in the design of the study and interpretation of data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
4977773	27503259	AC	2	were responsible for study design|supervised the study and significantly contributed towards manuscript preparation	were responsible for study design	Conceived and designed the experiments	Methodology	YES
4977773	27503259	AC	2	were responsible for study design|supervised the study and significantly contributed towards manuscript preparation	supervised the study and significantly contributed towards manuscript preparation	Wrote the paper	Supervision|Writing - Original Draft	YES
4977773	27503259	JG	2	contributed towards data analysis	contributed towards data analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
4977773	27503259	ZJSD	2	were responsible for study design|processed the data and performed analyses and drafted the manuscript	were responsible for study design	Conceived and designed the experiments	Methodology	YES
4977773	27503259	ZJSD	2	were responsible for study design|processed the data and performed analyses and drafted the manuscript	processed the data and performed analyses and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Formal analysis|Investigation|Writing - Original Draft	YES
2923102	20691049	MMK	2	participated in the design of the study, data collection, data analysis, and writing of the manuscript	participated in the design of the study, data collection, data analysis, and writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
2923102	20691049	MWK	2	participated in revising the manuscript, and giving final approval of the version to be published	participated in revising the manuscript, and giving final approval of the version to be published	Wrote the paper	Writing - Review & Editing	YES
2923102	20691049	PNK	2	participated in the design of the study, and reviewing the manuscript	participated in the design of the study, and reviewing the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
2923102	20691049	WCB	2	participated in the design of the study, data collection, and writing of the manuscript	participated in the design of the study, data collection, and writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5408559	28503184	AF	PLoS52	designed the research|performed the experiments|wrote the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
5408559	28503184	AF	PLoS52	designed the research|performed the experiments|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5408559	28503184	AF	PLoS52	designed the research|performed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5408559	28503184	EB	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5408559	28503184	MH	PLoS52	designed the research|performed the experiments|wrote the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
5408559	28503184	MH	PLoS52	designed the research|performed the experiments|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5408559	28503184	MH	PLoS52	designed the research|performed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5408559	28503184	MS	PLoS52	designed the research|wrote the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
5408559	28503184	MS	PLoS52	designed the research|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5408559	28503184	NN	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5456332	28933356	A.B.	PLoS52	conceived and designed the experiments|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5456332	28933356	A.B.	PLoS52	conceived and designed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5456332	28933356	E.V.	PLoS52	analysed the data|wrote the paper	analysed the data	Analyzed the data	Formal analysis	YES
5456332	28933356	E.V.	PLoS52	analysed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5456332	28933356	R.R.	PLoS52	performed the experiments|analysed the data	performed the experiments	Performed the experiments	Investigation	YES
5456332	28933356	R.R.	PLoS52	performed the experiments|analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
2924265	20684760	All authors	2	have had some involvement in the writing of the paper and have read and approved the final manuscript	have had some involvement in the writing of the paper and have read and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
2924265	20684760	LFU	2	with the serial sophid databases	with the serial sophid databases	Contributed reagents/materials/analysis tools	Software	YES
2924265	20684760	SMG	2	completed all the statistical analysis, wrote the first draft of the paper, and made alterations to the paper according to suggestions from the other authors	completed all the statistical analysis, wrote the first draft of the paper, and made alterations to the paper according to suggestions from the other authors	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
2924265	20684760	VCD	2	supervised the project and provided important advice and insight into the analyses and writing of the paper	supervised the project and provided important advice and insight into the analyses and writing of the paper	Analyzed the data|Wrote the paper	Formal analysis|Supervision|Writing - Original Draft	YES
4977848	27503142	AS	2	performed the bioinformatics and the molecular biology and helped in the preparation of this manuscript	performed the bioinformatics and the molecular biology and helped in the preparation of this manuscript	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4977848	27503142	DW	2	conceived of the study, assisted with the bioinformatic analysis, and wrote the manuscript	conceived of the study, assisted with the bioinformatic analysis, and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
4383306	25866769	Guang Yang	2	contributed equally to this work	contributed equally to this work	-	-	NO
4383306	25866769	Wei Li	2	contributed equally to this work	contributed equally to this work	-	-	NO
5456333	28933364	C.P.	2	did an extensive literature review and wrote the first draft	did an extensive literature review and wrote the first draft	Wrote the paper	Formal analysis|Writing - Original Draft	YES
5456333	28933364	J.R.	2	did some of the literature review and participated in writing the manuscript	did some of the literature review and participated in writing the manuscript	Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5456333	28933364	Q.Z.	2	did some of the literature review and participated in writing the manuscript	did some of the literature review and participated in writing the manuscript	Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5456333	28933364	S.M.	2	did some of the literature review and participated in writing the manuscript	did some of the literature review and participated in writing the manuscript	Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5456333	28933364	X.-B.Z.	2	coordinated the work and did extensive writing	coordinated the work and did extensive writing	Wrote the paper	Project administration	YES
2924266	20687954	AVDS	2	participated in the development and design of the project and protocol, provided technical expertise in the development and interpretation of behavioural assessments, and reviewed and edited the manuscript	participated in the development and design of the project and protocol, provided technical expertise in the development and interpretation of behavioural assessments, and reviewed and edited the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
2924266	20687954	CW	2	conceived of the study, developed the protocol and instruments, oversaw field implementation, and reviewed and edited the manuscript	conceived of the study, developed the protocol and instruments, oversaw field implementation, and reviewed and edited the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
2924266	20687954	ETM	2	participated in the development of the study protocol, data collection instruments and procedures, monitored field operations and data, led the analysis, and drafted the manuscript	participated in the development of the study protocol, data collection instruments and procedures, monitored field operations and data, led the analysis, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Supervision|Writing - Original Draft	YES
2924266	20687954	FS	2	provided clinical technical assistance in the oversight of safety issues, and reviewed and edited the manuscript	provided clinical technical assistance in the oversight of safety issues, and reviewed and edited the manuscript	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Review & Editing	YES
2924266	20687954	HC	2	performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
2924266	20687954	PM	2	coordinated and managed the data collection, and participated in the development of instruments and procedures	coordinated and managed the data collection, and participated in the development of instruments and procedures	Performed the experiments|Analyzed the data	Data curation|Investigation|Project administration	YES
2924266	20687954	TC	2	oversaw the field site, provided clinical expertise to the protocol development, and attended to all clinical and safety-related issues, as applicable	oversaw the field site, provided clinical expertise to the protocol development, and attended to all clinical and safety-related issues, as applicable	Conceived and designed the experiments	Methodology|Supervision	YES
2924266	20687954	TRM	2	participated in the development and design of the project and protocol, provided clinical input on data, and reviewed and edited the manuscript	participated in the development and design of the project and protocol, provided clinical input on data, and reviewed and edited the manuscript	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5409215	28503182	AM	2	critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5409215	28503182	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5409215	28503182	CW	2	made helpful suggestions on the manuscript and paticipated in the development of the population snp markers	made helpful suggestions on the manuscript and paticipated in the development of the population snp markers	-	-	NO
5409215	28503182	CZ	2	carried out the genotyping experiments	carried out the genotyping experiments	Performed the experiments	Investigation	YES
5409215	28503182	DF	2	provided plant materials, designed, led, and coordinated the overall study	provided plant materials, designed, led, and coordinated the overall study	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Project administration|Resources	YES
5409215	28503182	SF	2	made helpful suggestions on the manuscript and paticipated in the development of the population snp markers	made helpful suggestions on the manuscript and paticipated in the development of the population snp markers	-	-	NO
5409215	28503182	YH	2	provided plant materials, designed, led, and coordinated the overall study	provided plant materials, designed, led, and coordinated the overall study	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Project administration|Resources	YES
2925333	20678207	All authors	PLoS52	contributed to the writing of the manuscript, and all authors approved the manuscript for publication	contributed to the writing of the manuscript, and all authors approved the manuscript for publication	Wrote the paper	Writing - Original Draft	YES
2925333	20678207	CAB	PLoS52	collected the data	collected the data	Performed the experiments	Investigation	YES
2925333	20678207	DKE	PLoS52	designed the study|analyzed the data|interpreted the data	designed the study	Conceived and designed the experiments	Methodology	YES
2925333	20678207	DKE	PLoS52	designed the study|analyzed the data|interpreted the data	analyzed the data	Analyzed the data	Formal analysis	YES
2925333	20678207	DKE	PLoS52	designed the study|analyzed the data|interpreted the data	interpreted the data	Analyzed the data	Formal analysis	YES
2925333	20678207	FD	PLoS52	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
2925333	20678207	PAC	PLoS52	designed the study|collected the data|interpreted the data	designed the study	Conceived and designed the experiments	Methodology	YES
2925333	20678207	PAC	PLoS52	designed the study|collected the data|interpreted the data	collected the data	Performed the experiments	Investigation	YES
2925333	20678207	PAC	PLoS52	designed the study|collected the data|interpreted the data	interpreted the data	Analyzed the data	Formal analysis	YES
2925333	20678207	PC	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
4977872	27503467	JZS	2	analyzed the data and prepared the figures	analyzed the data and prepared the figures	Analyzed the data	Formal analysis|Visualization	YES
4977872	27503467	MYS	2	analyzed the data and prepared the figures|wrote the manuscript	analyzed the data and prepared the figures	Analyzed the data	Formal analysis|Visualization	YES
4977872	27503467	MYS	2	analyzed the data and prepared the figures|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4977872	27503467	YHH	2	designed and conducted the experiments|analyzed the data and prepared the figures|wrote the manuscript	designed and conducted the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4977872	27503467	YHH	2	designed and conducted the experiments|analyzed the data and prepared the figures|wrote the manuscript	analyzed the data and prepared the figures	Analyzed the data	Formal analysis|Visualization	YES
4977872	27503467	YHH	2	designed and conducted the experiments|analyzed the data and prepared the figures|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4977872	27503467	YY	2	analyzed the data and prepared the figures|prepared the samples|wrote the manuscript	analyzed the data and prepared the figures	Analyzed the data	Formal analysis|Visualization	YES
4977872	27503467	YY	2	analyzed the data and prepared the figures|prepared the samples|wrote the manuscript	prepared the samples	Performed the experiments	Investigation	YES
4977872	27503467	YY	2	analyzed the data and prepared the figures|prepared the samples|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5410566	28507559	FF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5410566	28507559	FF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5410566	28507559	FF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5410566	28507559	XC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5410566	28507559	XY	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5410566	28507559	YC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5410566	28507559	YK	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5410566	28507559	YK	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2941743	20822522	ASF	2	undertook statistical analysis, data discussion and manuscript preparation	undertook statistical analysis, data discussion and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
2941743	20822522	CF	2	undertook clinical coordination, patient interaction, data discussion and manuscript preparation	undertook clinical coordination, patient interaction, data discussion and manuscript preparation	Performed the experiments|Wrote the paper	Investigation|Project administration|Writing - Original Draft	YES
2941743	20822522	DEXA	2	data analysis, data discussion and manuscript preparation	data analysis, data discussion and manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
2941743	20822522	DS	2	undertook database management, data discussion and manuscript revision	undertook database management, data discussion and manuscript revision	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Data curation|Investigation|Software|Writing - Review & Editing	YES
2941743	20822522	EP	2	undertook data discussion and manuscript revision	undertook data discussion and manuscript revision	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
2941743	20822522	IS	2	undertook clinical site supervision, clinical coordination, patient interaction, data discussion and manuscript preparation	undertook clinical site supervision, clinical coordination, patient interaction, data discussion and manuscript preparation	Performed the experiments|Wrote the paper	Investigation|Project administration|Supervision|Writing - Original Draft	YES
2941743	20822522	LA	2	was responsible for study design, data management, critical analysis, manuscript and illustration preparation	was responsible for study design, data management, critical analysis, manuscript and illustration preparation	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Data curation|Formal analysis|Methodology|Visualization|Writing - Original Draft	YES
2941743	20822522	LJM	2	undertook study design, immunology laboratory supervision, critical analysis and manuscript preparation	undertook study design, immunology laboratory supervision, critical analysis and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Supervision|Writing - Original Draft	YES
2941743	20822522	NJC	2	undertook leptin and lipid assessment, critical analysis, data discussion and manuscript preparation	undertook leptin and lipid assessment, critical analysis, data discussion and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
2941743	20822522	RG	2	undertook statistical and epidemiology analysis, data discussion and manuscript preparation	undertook statistical and epidemiology analysis, data discussion and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
2941743	20822522	RW	2	undertook leptin and lipid assessment, critical analysis, data discussion and manuscript revision	undertook leptin and lipid assessment, critical analysis, data discussion and manuscript revision	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
2941743	20822522	TvdM	2	undertook mri data analysis, data discussion and manuscript revision	undertook mri data analysis, data discussion and manuscript revision	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
2941743	20822522	WS	2	undertook clinical laboratory test performance, data discussion and manuscript preparation	undertook clinical laboratory test performance, data discussion and manuscript preparation	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
2941743	20822522	XY	2	undertook statistical analysis, data discussion and manuscript revision	undertook statistical analysis, data discussion and manuscript revision	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
4977884	27502787	All authors	2	contributed to the writing and revision of the manuscript	contributed to the writing and revision of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4977884	27502787	CSH	2	designed and executed the model generation and analysis with|conceived of and oversaw this project	designed and executed the model generation and analysis with	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4977884	27502787	CSH	2	designed and executed the model generation and analysis with|conceived of and oversaw this project	conceived of and oversaw this project	Conceived and designed the experiments	Conceptualization|Supervision	YES
4977884	27502787	Core Model Viewer	2	website development	website development	Contributed reagents/materials/analysis tools	Software	YES
4977884	27502787	FX	2	contributed in generating phylogenetic trees and visualizing pathway data	contributed in generating phylogenetic trees and visualizing pathway data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Investigation|Resources|Visualization	YES
4977884	27502787	JNE	2	designed and executed the model generation and analysis with|designed the model template and the media conditions for the analysis	designed and executed the model generation and analysis with	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4977884	27502787	JNE	2	designed and executed the model generation and analysis with|designed the model template and the media conditions for the analysis	designed the model template and the media conditions for the analysis	Conceived and designed the experiments|Performed the experiments	Methodology	YES
4977884	27502787	PW	2	designed and executed the model generation and analysis with	designed and executed the model generation and analysis with	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4977884	27502787	RLS	2	contributed to the design and staging of our modeling infrastructure	contributed to the design and staging of our modeling infrastructure	Conceived and designed the experiments|Performed the experiments	Methodology	YES
4977884	27502787	RO	2	contributed in determining linear pathways	contributed in determining linear pathways	-	-	NO
4977884	27502787	all other authors	2	assisted with the designed and executed the model generation and analysis with	assisted with the designed and executed the model generation and analysis with	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5410596	28507555	AW	2	performed the field experiment	performed the field experiment	Performed the experiments	Investigation	YES
5410596	28507555	BX	2	contributed to the writing and revision	contributed to the writing and revision	Wrote the paper	Writing - Review & Editing	YES
5410596	28507555	JW	2	performed the nursery experiment	performed the nursery experiment	Performed the experiments	Investigation	YES
5410596	28507555	KS	2	contributed to the writing and revision	contributed to the writing and revision	Wrote the paper	Writing - Review & Editing	YES
5410596	28507555	SQ	2	performed the field experiment	performed the field experiment	Performed the experiments	Investigation	YES
5410596	28507555	SZ	2	contributed to the writing and revision	contributed to the writing and revision	Wrote the paper	Writing - Review & Editing	YES
5410596	28507555	YC	2	designed the experiments and performed data analyses|contributed to the writing and revision	designed the experiments and performed data analyses	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5410596	28507555	YC	2	designed the experiments and performed data analyses|contributed to the writing and revision	contributed to the writing and revision	Wrote the paper	Writing - Review & Editing	YES
5410596	28507555	YD	2	designed the experiments and performed data analyses|contributed to the writing and revision	designed the experiments and performed data analyses	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5410596	28507555	YD	2	designed the experiments and performed data analyses|contributed to the writing and revision	contributed to the writing and revision	Wrote the paper	Writing - Review & Editing	YES
5410596	28507555	YF	2	designed the experiments and performed data analyses|performed the nursery experiment|performed the field experiment|contributed to the writing and revision	designed the experiments and performed data analyses	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5410596	28507555	YF	2	designed the experiments and performed data analyses|performed the nursery experiment|performed the field experiment|contributed to the writing and revision	performed the nursery experiment	Performed the experiments	Investigation	YES
5410596	28507555	YF	2	designed the experiments and performed data analyses|performed the nursery experiment|performed the field experiment|contributed to the writing and revision	performed the field experiment	Performed the experiments	Investigation	YES
5410596	28507555	YF	2	designed the experiments and performed data analyses|performed the nursery experiment|performed the field experiment|contributed to the writing and revision	contributed to the writing and revision	Wrote the paper	Writing - Review & Editing	YES
2944311	20731835	AO	2	was co-principal investigator of the mkv2, oversaw the design, implementation and interpretation of all the studies in this paper, and contributed substantially to various drafts of the manuscript	was co-principal investigator of the mkv2, oversaw the design, implementation and interpretation of all the studies in this paper, and contributed substantially to various drafts of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Funding acquisition|Investigation|Methodology|Supervision|Writing - Original Draft	YES
2944311	20731835	BA	2	was lead researcher for the data collection of all components of this study, was involved in the design, led the implementation of the simulated patients study, and co-wrote the first iteration of the manuscript	was lead researcher for the data collection of all components of this study, was involved in the design, led the implementation of the simulated patients study, and co-wrote the first iteration of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
2944311	20731835	CK	2	led the implementation of the health component, supported the design and implementation of the research, and commented on various drafts of this paper	led the implementation of the health component, supported the design and implementation of the research, and commented on various drafts of this paper	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
2944311	20731835	ColK	2	performed the final statistical analyses for the health worker training data	performed the final statistical analyses for the health worker training data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
2944311	20731835	JC	2	was co-principal investigator of the mkv2, and supported the research on all phases of mkv2	was co-principal investigator of the mkv2, and supported the research on all phases of mkv2	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
2944311	20731835	KN	2	was involved in the design and data collection, conducted most of the training observations and analysis, and co-wrote the first iteration of training evaluation section of this manuscript	was involved in the design and data collection, conducted most of the training observations and analysis, and co-wrote the first iteration of training evaluation section of this manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
2944814	20840741	BW	2	designed and coordinated the study, participated in data cleaning and data analysis, and was the lead author on this paper	designed and coordinated the study, participated in data cleaning and data analysis, and was the lead author on this paper	Conceived and designed the experiments|Analyzed the data	Data curation|Formal analysis|Methodology|Project administration	YES
2944814	20840741	ED	2	performed data cleaning and data analysis	performed data cleaning and data analysis	Analyzed the data	Data curation|Formal analysis	YES
2944814	20840741	SM	2	contributed to data analysis, writing of the manuscript, and editing for important content	contributed to data analysis, writing of the manuscript, and editing for important content	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5456335	28933365	B.C.M.	2	performed translational research|wrote the manuscript and gathered translational evidence for milks role as an epigenetic regulator	performed translational research	Performed the experiments	Investigation	YES
5456335	28933365	B.C.M.	2	performed translational research|wrote the manuscript and gathered translational evidence for milks role as an epigenetic regulator	wrote the manuscript and gathered translational evidence for milks role as an epigenetic regulator	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5456335	28933365	Both authors	2	proofread and approved the final manuscript	proofread and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5456335	28933365	G.S.	2	performed translational research|supported the manuscript especially in the field of lipid metabolism	performed translational research	Performed the experiments	Investigation	YES
5456335	28933365	G.S.	2	performed translational research|supported the manuscript especially in the field of lipid metabolism	supported the manuscript especially in the field of lipid metabolism	Performed the experiments	Investigation	YES
5410599	28507557	EC	7	experimental analysis	experimental analysis	-	-	NO
5410599	28507557	H-JB	7	drafting the work	drafting the work	Wrote the paper	Writing - Original Draft	YES
5410599	28507557	HK	7	revising for important intellectual content and interpretation of the work	revising for important intellectual content and interpretation of the work	Analyzed the data	Formal analysis	YES
5410599	28507557	Y-OK	7	substantial contributions to the conception or design of the work and writing of manuscript	substantial contributions to the conception or design of the work and writing of manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4977886	27507061	All authors	PLoS52	critically reviewed the manuscript for intellectual content and gave final approval for the version to be published	critically reviewed the manuscript for intellectual content and gave final approval for the version to be published	Wrote the paper	Writing - Review & Editing	YES
4977886	27507061	BYR	PLoS52	supervised the design of the study	supervised the design of the study	Conceived and designed the experiments	Methodology|Supervision	YES
4977886	27507061	MGP	PLoS52	draft the manuscript|supervised the design of the study	draft the manuscript	Wrote the paper	Writing - Original Draft	YES
4977886	27507061	MGP	PLoS52	draft the manuscript|supervised the design of the study	supervised the design of the study	Conceived and designed the experiments	Methodology|Supervision	YES
4977886	27507061	MSR	PLoS52	performed the experiments|analyzed the data and performed the artwork|draft the manuscript	performed the experiments	Performed the experiments	Investigation	YES
4977886	27507061	MSR	PLoS52	performed the experiments|analyzed the data and performed the artwork|draft the manuscript	analyzed the data and performed the artwork	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
4977886	27507061	MSR	PLoS52	performed the experiments|analyzed the data and performed the artwork|draft the manuscript	draft the manuscript	Wrote the paper	Writing - Original Draft	YES
4977886	27507061	SJY	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
4977886	27507061	WSK	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
4977886	27507061	YJP	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
2954932	20863399	CW	2	was involved in the study design, data analysis, interpretation and gave input into the final version of the article	was involved in the study design, data analysis, interpretation and gave input into the final version of the article	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
2954932	20863399	JO-O	2	supervised the field work and provided comments on the study results and their relevance to the health care services as well as commented on the first draft of the article	supervised the field work and provided comments on the study results and their relevance to the health care services as well as commented on the first draft of the article	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Original Draft	YES
2954932	20863399	PD	2	was involved in study design, field work execution, data analysis, interpretation and writing the first draft of the article	was involved in study design, field work execution, data analysis, interpretation and writing the first draft of the article	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
2954932	20863399	TR	2	provided input into the study design, supervised the field work and commented on the study results and their interpretation as well as the first draft of the article	provided input into the study design, supervised the field work and commented on the study results and their interpretation as well as the first draft of the article	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Supervision|Writing - Original Draft	YES
2954932	20863399	WK	2	helped with study design, data analysis and interpretation and wrote the final version of the manuscript	helped with study design, data analysis and interpretation and wrote the final version of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5410603	28507558	JP	2	conceived and designed the research|prepared materials, designed and performed the research, and wrote the original manuscript	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5410603	28507558	JP	2	conceived and designed the research|prepared materials, designed and performed the research, and wrote the original manuscript	prepared materials, designed and performed the research, and wrote the original manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5410603	28507558	JY	2	conceived and designed the research|revised thoroughly the manuscript and finalized the manuscript	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5410603	28507558	JY	2	conceived and designed the research|revised thoroughly the manuscript and finalized the manuscript	revised thoroughly the manuscript and finalized the manuscript	Wrote the paper	Writing - Review & Editing	YES
5410603	28507558	NL	2	participated in the preparing materials	participated in the preparing materials	Performed the experiments	Investigation	YES
5410603	28507558	XC	2	participated in the preparing materials	participated in the preparing materials	Performed the experiments	Investigation	YES
5410603	28507558	XQ	2	participated in the preparing materials	participated in the preparing materials	Performed the experiments	Investigation	YES
2978127	20925943	AM	2	participated in the design, supervised study implementation and drafted the manuscript|participated in study implementation and data collection|participated in data analysis and provided technical expertise|conceived the study, and participated in its design and coordination	participated in the design, supervised study implementation and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Supervision|Writing - Original Draft	YES
2978127	20925943	AM	2	participated in the design, supervised study implementation and drafted the manuscript|participated in study implementation and data collection|participated in data analysis and provided technical expertise|conceived the study, and participated in its design and coordination	participated in study implementation and data collection	Performed the experiments	Investigation	YES
2978127	20925943	AM	2	participated in the design, supervised study implementation and drafted the manuscript|participated in study implementation and data collection|participated in data analysis and provided technical expertise|conceived the study, and participated in its design and coordination	participated in data analysis and provided technical expertise	Analyzed the data	Formal analysis	YES
2978127	20925943	AM	2	participated in the design, supervised study implementation and drafted the manuscript|participated in study implementation and data collection|participated in data analysis and provided technical expertise|conceived the study, and participated in its design and coordination	conceived the study, and participated in its design and coordination	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
2978127	20925943	AS	2	participated in data analysis and provided technical expertise|conceived the study, and participated in its design and coordination	participated in data analysis and provided technical expertise	Analyzed the data	Formal analysis	YES
2978127	20925943	AS	2	participated in data analysis and provided technical expertise|conceived the study, and participated in its design and coordination	conceived the study, and participated in its design and coordination	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
2978127	20925943	EM	2	conceived the study, and participated in its design and coordination	conceived the study, and participated in its design and coordination	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
2978127	20925943	GW	2	participated in data analysis and provided technical expertise	participated in data analysis and provided technical expertise	Analyzed the data	Formal analysis	YES
2978127	20925943	JK	2	participated in data analysis and provided technical expertise|conceived the study, and participated in its design and coordination	participated in data analysis and provided technical expertise	Analyzed the data	Formal analysis	YES
2978127	20925943	JK	2	participated in data analysis and provided technical expertise|conceived the study, and participated in its design and coordination	conceived the study, and participated in its design and coordination	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
2978127	20925943	LS	2	participated in study implementation and data collection	participated in study implementation and data collection	Performed the experiments	Investigation	YES
2978127	20925943	WC	2	participated in study implementation and data collection|conceived the study, and participated in its design and coordination	participated in study implementation and data collection	Performed the experiments	Investigation	YES
2978127	20925943	WC	2	participated in study implementation and data collection|conceived the study, and participated in its design and coordination	conceived the study, and participated in its design and coordination	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
4979106	27507407	JL	2	all contributed to pcr genotyping	all contributed to pcr genotyping	Performed the experiments	Investigation	YES
4979106	27507407	JR	2	all contributed to pcr genotyping	all contributed to pcr genotyping	Performed the experiments	Investigation	YES
4979106	27507407	LQ	2	analysed the phenotypic data	analysed the phenotypic data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4979106	27507407	LS	2	all contributed to pcr genotyping	all contributed to pcr genotyping	Performed the experiments	Investigation	YES
4979106	27507407	QY	2	designed the experiment	designed the experiment	Conceived and designed the experiments	Methodology	YES
4979106	27507407	WQ	2	performed the experiments and wrote the manuscript	performed the experiments and wrote the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4979106	27507407	XZ	2	performed qtl analysis	performed qtl analysis	Performed the experiments	Investigation	YES
4979106	27507407	YS	2	all contributed to pcr genotyping	all contributed to pcr genotyping	Performed the experiments	Investigation	YES
4979106	27507407	ZC	2	provided valuable suggestions for the experiment	provided valuable suggestions for the experiment	-	-	NO
5456336	28933357	E.S.D.	2	conceived the study|designed the study|recruited the study subjects and collected specimens|carried out data analysis|wrote the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5456336	28933357	E.S.D.	2	conceived the study|designed the study|recruited the study subjects and collected specimens|carried out data analysis|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5456336	28933357	E.S.D.	2	conceived the study|designed the study|recruited the study subjects and collected specimens|carried out data analysis|wrote the manuscript	recruited the study subjects and collected specimens	Performed the experiments	Investigation	YES
5456336	28933357	E.S.D.	2	conceived the study|designed the study|recruited the study subjects and collected specimens|carried out data analysis|wrote the manuscript	carried out data analysis	Analyzed the data	Formal analysis	YES
5456336	28933357	E.S.D.	2	conceived the study|designed the study|recruited the study subjects and collected specimens|carried out data analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5456336	28933357	I.A.-B.	2	designed the study|recruited the study subjects and collected specimens|carried out data analysis|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5456336	28933357	I.A.-B.	2	designed the study|recruited the study subjects and collected specimens|carried out data analysis|wrote the manuscript	recruited the study subjects and collected specimens	Performed the experiments	Investigation	YES
5456336	28933357	I.A.-B.	2	designed the study|recruited the study subjects and collected specimens|carried out data analysis|wrote the manuscript	carried out data analysis	Analyzed the data	Formal analysis	YES
5456336	28933357	I.A.-B.	2	designed the study|recruited the study subjects and collected specimens|carried out data analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5456336	28933357	J.A.O.	2	designed the study|recruited the study subjects and collected specimens|carried out laboratory analysis|carried out data analysis|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5456336	28933357	J.A.O.	2	designed the study|recruited the study subjects and collected specimens|carried out laboratory analysis|carried out data analysis|wrote the manuscript	recruited the study subjects and collected specimens	Performed the experiments	Investigation	YES
5456336	28933357	J.A.O.	2	designed the study|recruited the study subjects and collected specimens|carried out laboratory analysis|carried out data analysis|wrote the manuscript	carried out laboratory analysis	Performed the experiments	Investigation	YES
5456336	28933357	J.A.O.	2	designed the study|recruited the study subjects and collected specimens|carried out laboratory analysis|carried out data analysis|wrote the manuscript	carried out data analysis	Analyzed the data	Formal analysis	YES
5456336	28933357	J.A.O.	2	designed the study|recruited the study subjects and collected specimens|carried out laboratory analysis|carried out data analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5456336	28933357	S.D.	2	designed the study|recruited the study subjects and collected specimens|carried out laboratory analysis|carried out data analysis	designed the study	Conceived and designed the experiments	Methodology	YES
5456336	28933357	S.D.	2	designed the study|recruited the study subjects and collected specimens|carried out laboratory analysis|carried out data analysis	recruited the study subjects and collected specimens	Performed the experiments	Investigation	YES
5456336	28933357	S.D.	2	designed the study|recruited the study subjects and collected specimens|carried out laboratory analysis|carried out data analysis	carried out laboratory analysis	Performed the experiments	Investigation	YES
5456336	28933357	S.D.	2	designed the study|recruited the study subjects and collected specimens|carried out laboratory analysis|carried out data analysis	carried out data analysis	Analyzed the data	Formal analysis	YES
4383345	25866766	Shanshan Wang	2	contributed equally to this study	contributed equally to this study	-	-	NO
4383345	25866766	Yunliang Wang	2	contributed equally to this study	contributed equally to this study	-	-	NO
2984577	20955629	AMM	2	participated in the development and design of the project and protocol, provided scientific input in analysis, and reviewed and edited the manuscript	participated in the development and design of the project and protocol, provided scientific input in analysis, and reviewed and edited the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft|Writing - Review & Editing	YES
2984577	20955629	AVDS	2	conceived of the study, participated in the development of the study protocols, led the analysis, and drafted the manuscript	conceived of the study, participated in the development of the study protocols, led the analysis, and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
2984577	20955629	HC	2	performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
4979108	27506674	HKK	2	conceived of the study and participated in its design and coordination, carried out drug administration studies and sample collection, performed data analysis and drafted the manuscript and approved of the final manuscript	conceived of the study and participated in its design and coordination, carried out drug administration studies and sample collection, performed data analysis and drafted the manuscript and approved of the final manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Project administration|Writing - Original Draft|Writing - Review & Editing	YES
4979108	27506674	LMH	2	participated in study design, carried out drug administration studies and sample collection, helped to draft the manuscript and approved of the final manuscript	participated in study design, carried out drug administration studies and sample collection, helped to draft the manuscript and approved of the final manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
4979108	27506674	NC	2	carried out microarray and tlda analysis, participated in drafting the manuscript and final manuscript approval	carried out microarray and tlda analysis, participated in drafting the manuscript and final manuscript approval	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
4979108	27506674	PHK	2	conducted the statistical analysis of tlda results as well as assisting with drafting manuscript and final approval of the manuscript	conducted the statistical analysis of tlda results as well as assisting with drafting manuscript and final approval of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4979108	27506674	SJS	2	participated in study design, carried out drug administration studies and sample collection and approved the final manuscript	participated in study design, carried out drug administration studies and sample collection and approved the final manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
5410604	28507552	BI	PLoS5	Attended discussion and part of experiments	Attended discussion and part of experiments	-	-	NO
5410604	28507552	JH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Edited and revised the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5410604	28507552	JH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Edited and revised the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5410604	28507552	JH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Edited and revised the manuscript	Edited and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5410604	28507552	YC	PLoS5	Performed the experiments and analyzed the data|Prepared the manuscript	Performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5410604	28507552	YC	PLoS5	Performed the experiments and analyzed the data|Prepared the manuscript	Prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5410604	28507552	YH	PLoS5	Attended discussion and part of experiments	Attended discussion and part of experiments	-	-	NO
5410604	28507552	YW	PLoS5	Maintained the experimental platform and performed bench work	Maintained the experimental platform and performed bench work	Performed the experiments	Investigation	YES
5410604	28507552	YZ	PLoS5	Performed the experiments and analyzed the data	Performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5410604	28507552	ZL	PLoS5	Attended discussion and part of experiments	Attended discussion and part of experiments	-	-	NO
2984578	20979651	Both authors	2	contributed to the manuscript, and saw and approved the final version	contributed to the manuscript, and saw and approved the final version	-	-	NO
2984578	20979651	GT	2	participated in the design of the study and drafted the manuscript	participated in the design of the study and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
2984578	20979651	HW	2	carried out the analyses and drafted the manuscript	carried out the analyses and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5456338	28933358	A.L.K.D.-R.	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5456338	28933358	A.L.K.D.-R.	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5456338	28933358	A.L.K.D.-R.	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5456338	28933358	A.L.K.D.-R.	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5456338	28933358	C.E.P.	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5456338	28933358	C.E.P.	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5456338	28933358	M.R.J.	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5456338	28933358	M.R.J.	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5456338	28933358	S.B.	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2987791	20973946	J-FL	2	led the design and analysis of the expert opinion check experts survey, developed the scientific content of the experts meeting, and drafted the manuscript	led the design and analysis of the expert opinion check experts survey, developed the scientific content of the experts meeting, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
2987791	20973946	MC	2	contributed to the development of the experts meeting agenda and analysis of meeting outcomes	contributed to the development of the experts meeting agenda and analysis of meeting outcomes	-	-	NO
5410614	28507551	All authors	2	have read and approved the final manuscript	have read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5410614	28507551	CB	2	conducted genotyping of the association mapping panel	conducted genotyping of the association mapping panel	Performed the experiments	Investigation	YES
5410614	28507551	CS	2	planned and designed the research|prepared the manuscript|edited the manuscript for publication	planned and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5410614	28507551	CS	2	planned and designed the research|prepared the manuscript|edited the manuscript for publication	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5410614	28507551	CS	2	planned and designed the research|prepared the manuscript|edited the manuscript for publication	edited the manuscript for publication	Wrote the paper	Writing - Review & Editing	YES
5410614	28507551	NA	2	performed the field experiment|conducted genotyping of the association mapping panel|conducted structure and tassel analysis|prepared the manuscript	performed the field experiment	Performed the experiments	Investigation	YES
5410614	28507551	NA	2	performed the field experiment|conducted genotyping of the association mapping panel|conducted structure and tassel analysis|prepared the manuscript	conducted genotyping of the association mapping panel	Performed the experiments	Investigation	YES
5410614	28507551	NA	2	performed the field experiment|conducted genotyping of the association mapping panel|conducted structure and tassel analysis|prepared the manuscript	conducted structure and tassel analysis	Performed the experiments	Investigation	YES
5410614	28507551	NA	2	performed the field experiment|conducted genotyping of the association mapping panel|conducted structure and tassel analysis|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5410614	28507551	RS	2	planned and designed the research|organized bioinformatics analysis|prepared the manuscript|edited the manuscript for publication	planned and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5410614	28507551	RS	2	planned and designed the research|organized bioinformatics analysis|prepared the manuscript|edited the manuscript for publication	organized bioinformatics analysis	-	Formal analysis	YES
5410614	28507551	RS	2	planned and designed the research|organized bioinformatics analysis|prepared the manuscript|edited the manuscript for publication	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5410614	28507551	RS	2	planned and designed the research|organized bioinformatics analysis|prepared the manuscript|edited the manuscript for publication	edited the manuscript for publication	Wrote the paper	Writing - Review & Editing	YES
5410614	28507551	SMS	2	performed the field experiment	performed the field experiment	Performed the experiments	Investigation	YES
5410614	28507551	SPS	2	performed the field experiment	performed the field experiment	Performed the experiments	Investigation	YES
5410614	28507551	TN	2	conducted structure and tassel analysis	conducted structure and tassel analysis	Performed the experiments	Investigation	YES
5410614	28507551	TS	2	conducted genotyping of the association mapping panel	conducted genotyping of the association mapping panel	Performed the experiments	Investigation	YES
4979109	27507015	DJK	2	performed computational and statistical data analyses	performed computational and statistical data analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4979109	27507015	JJ	2	performed experimental analyses	performed experimental analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4979109	27507015	JK	2	performed computational and statistical data analyses|co-wrote the manuscript and conceived the study	performed computational and statistical data analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4979109	27507015	JK	2	performed computational and statistical data analyses|co-wrote the manuscript and conceived the study	co-wrote the manuscript and conceived the study	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4979109	27507015	LMC	2	performed computational and statistical data analyses	performed computational and statistical data analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4979109	27507015	MW	2	co-wrote the manuscript and conceived the study	co-wrote the manuscript and conceived the study	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4979109	27507015	RAM	2	performed experimental analyses	performed experimental analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4979109	27507015	SMB	2	performed experimental analyses	performed experimental analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
2991285	21047391	AK	2	performed the statistical analysis, and wrote the manuscript	performed the statistical analysis, and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
2991285	21047391	BC	2	participated in its design and coordination, and helped draft the manuscript	participated in its design and coordination, and helped draft the manuscript	Conceived and designed the experiments|Wrote the paper	Project administration|Writing - Original Draft	YES
2991285	21047391	DN	2	participated in its design and coordination, and helped draft the manuscript	participated in its design and coordination, and helped draft the manuscript	Conceived and designed the experiments|Wrote the paper	Project administration|Writing - Original Draft	YES
2991285	21047391	YM	2	conceived of the study, participated in its design and coordination, and helped draft the manuscript	conceived of the study, participated in its design and coordination, and helped draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
5456339	28933360	C.-Y.W.	PLoS52	conceived and designed the experiments|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5456339	28933360	C.-Y.W.	PLoS52	conceived and designed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5456339	28933360	C.E.	PLoS52	performed bat studies and collected fecal specimens	performed bat studies and collected fecal specimens	Performed the experiments	Investigation	YES
5456339	28933360	J.A.G.	PLoS52	performed bat studies and collected fecal specimens	performed bat studies and collected fecal specimens	Performed the experiments	Investigation	YES
5456339	28933360	J.A.L.	PLoS52	conceived and designed the experiments|performed the experiments|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5456339	28933360	J.A.L.	PLoS52	conceived and designed the experiments|performed the experiments|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5456339	28933360	J.A.L.	PLoS52	conceived and designed the experiments|performed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5456339	28933360	J.C.L.	PLoS52	performed the experiments|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5456339	28933360	J.C.L.	PLoS52	performed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5456339	28933360	J.G.M.Jr	PLoS52	conceived and designed the experiments|analyzed the data|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5456339	28933360	J.G.M.Jr	PLoS52	conceived and designed the experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5456339	28933360	J.G.M.Jr	PLoS52	conceived and designed the experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5456339	28933360	J.P.D.	PLoS52	conceived and designed the experiments|analyzed the data|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5456339	28933360	J.P.D.	PLoS52	conceived and designed the experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5456339	28933360	J.P.D.	PLoS52	conceived and designed the experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5456339	28933360	K.O.	PLoS52	performed bat studies and collected fecal specimens	performed bat studies and collected fecal specimens	Performed the experiments	Investigation	YES
5456339	28933360	L.A.S.	PLoS52	performed bat studies and collected fecal specimens	performed bat studies and collected fecal specimens	Performed the experiments	Investigation	YES
5456339	28933360	L.S.	PLoS52	performed bat studies and collected fecal specimens	performed bat studies and collected fecal specimens	Performed the experiments	Investigation	YES
5456339	28933360	M.S.	PLoS52	analyzed the data|performed phylogenetic analyses|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5456339	28933360	M.S.	PLoS52	analyzed the data|performed phylogenetic analyses|wrote the paper	performed phylogenetic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5456339	28933360	M.S.	PLoS52	analyzed the data|performed phylogenetic analyses|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5456339	28933360	T.P.	PLoS52	analyzed the data|performed phylogenetic analyses|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5456339	28933360	T.P.	PLoS52	analyzed the data|performed phylogenetic analyses|wrote the paper	performed phylogenetic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5456339	28933360	T.P.	PLoS52	analyzed the data|performed phylogenetic analyses|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5456339	28933360	T.S.B.	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5456339	28933360	T.S.B.	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5456339	28933360	T.S.B.	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5456339	28933360	T.S.B.	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
2992476	21054866	AB	2	contributed to the laboratory cost analysis	contributed to the laboratory cost analysis	Performed the experiments	Investigation	YES
2992476	21054866	AG	2	participated in the conception and design of the study and helped draft the manuscript	participated in the conception and design of the study and helped draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
2992476	21054866	All authors	2	have read and approved the final manuscript	have read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
2992476	21054866	CC	2	contributed to the laboratory cost analysis	contributed to the laboratory cost analysis	Performed the experiments	Investigation	YES
2992476	21054866	CL	2	participated in the design of the study and analysis of the data	participated in the design of the study and analysis of the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
2992476	21054866	GJD	2	participated in the design of the study and analysis of the data|participated in the conception and design of the study and helped draft the manuscript	participated in the design of the study and analysis of the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
2992476	21054866	GJD	2	participated in the design of the study and analysis of the data|participated in the conception and design of the study and helped draft the manuscript	participated in the conception and design of the study and helped draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
2992476	21054866	JG	2	developed the analysis tools	developed the analysis tools	-	-	NO
2992476	21054866	JJA	2	participated in the conception and design of the study and helped draft the manuscript	participated in the conception and design of the study and helped draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
2992476	21054866	MS	2	collected all the data and contributed to the analysis	collected all the data and contributed to the analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
2992476	21054866	TS	2	participated in the conception and design of the study and helped draft the manuscript	participated in the conception and design of the study and helped draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
2992476	21054866	VA	2	collected all the data and contributed to the analysis	collected all the data and contributed to the analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5410622	28507553	CB	2	for the aspects of molecular mechanisms of interactions|provided their knowledge in virology|wrote a first draft of the article, which was improved by suggestions from all authors	for the aspects of molecular mechanisms of interactions	Performed the experiments	Investigation	YES
5410622	28507553	CB	2	for the aspects of molecular mechanisms of interactions|provided their knowledge in virology|wrote a first draft of the article, which was improved by suggestions from all authors	provided their knowledge in virology	-	-	NO
5410622	28507553	CB	2	for the aspects of molecular mechanisms of interactions|provided their knowledge in virology|wrote a first draft of the article, which was improved by suggestions from all authors	wrote a first draft of the article, which was improved by suggestions from all authors	Wrote the paper	Writing - Original Draft	YES
5410622	28507553	CT	2	wrote a first draft of the article, which was improved by suggestions from all authors	wrote a first draft of the article, which was improved by suggestions from all authors	Wrote the paper	Writing - Original Draft	YES
5410622	28507553	DS	2	provided their knowledge in virology	provided their knowledge in virology	-	-	NO
5410622	28507553	EH	2	provided their knowledge in virology	provided their knowledge in virology	-	-	NO
5410622	28507553	H. Finally	2	wrote a first draft of the article, which was improved by suggestions from all authors	wrote a first draft of the article, which was improved by suggestions from all authors	Wrote the paper	Writing - Original Draft	YES
5410622	28507553	SC	2	for the aspects of molecular mechanisms of interactions	for the aspects of molecular mechanisms of interactions	Performed the experiments	Investigation	YES
5410622	28507553	SL	2	for the aspects of molecular mechanisms of interactions|provided their knowledge in virology|wrote a first draft of the article, which was improved by suggestions from all authors	for the aspects of molecular mechanisms of interactions	Performed the experiments	Investigation	YES
5410622	28507553	SL	2	for the aspects of molecular mechanisms of interactions|provided their knowledge in virology|wrote a first draft of the article, which was improved by suggestions from all authors	provided their knowledge in virology	-	-	NO
5410622	28507553	SL	2	for the aspects of molecular mechanisms of interactions|provided their knowledge in virology|wrote a first draft of the article, which was improved by suggestions from all authors	wrote a first draft of the article, which was improved by suggestions from all authors	Wrote the paper	Writing - Original Draft	YES
4979118	27506197	CI	2	provided conception, laboratory support, critical revision of the manuscript, and final approval of the version to be published	provided conception, laboratory support, critical revision of the manuscript, and final approval of the version to be published	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
4979118	27506197	JS	2	contributed the transcriptomic data and analysis	contributed the transcriptomic data and analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
4979118	27506197	KK	2	contributed the transcriptomic data and analysis	contributed the transcriptomic data and analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
4979118	27506197	NK	2	contributed the transcriptomic data and analysis	contributed the transcriptomic data and analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
4979118	27506197	PS	2	provided conception, laboratory support, critical revision of the manuscript, and final approval of the version to be published	provided conception, laboratory support, critical revision of the manuscript, and final approval of the version to be published	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
4979118	27506197	SFC	2	provided conception, laboratory support, critical revision of the manuscript, and final approval of the version to be published	provided conception, laboratory support, critical revision of the manuscript, and final approval of the version to be published	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
4979118	27506197	SS	2	performed the bioinformatics analyses and wrote the manuscript	performed the bioinformatics analyses and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4979118	27506197	TK	2	contributed the transcriptomic data and analysis	contributed the transcriptomic data and analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
4979118	27506197	TT	2	contributed the transcriptomic data and analysis	contributed the transcriptomic data and analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
4979118	27506197	WK	2	performed the western blot analysis and immunohistochemistry, and wrote the manuscript	performed the western blot analysis and immunohistochemistry, and wrote the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
2992477	21078150	IC	2	supervised data analysis, data interpretation and the writing up of the paper	supervised data analysis, data interpretation and the writing up of the paper	Analyzed the data|Wrote the paper	Formal analysis|Supervision|Writing - Original Draft	YES
2992477	21078150	KD	2	contributed to the development of the data collection tools, gave technical assistance to the project, and participated in data management and the interpretation of findings	contributed to the development of the data collection tools, gave technical assistance to the project, and participated in data management and the interpretation of findings	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Formal analysis|Investigation|Project administration|Resources	YES
2992477	21078150	MN	2	the first author of this paper, contributed to the design of the study, project management, data collection, analysis and interpretation of findings, and took a lead responsibility in writing up the paper	the first author of this paper, contributed to the design of the study, project management, data collection, analysis and interpretation of findings, and took a lead responsibility in writing up the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Data curation|Formal analysis|Investigation|Methodology|Project administration|Resources|Writing - Original Draft	YES
2992477	21078150	NJS	2	contributed to the development of data collection tools, data collection, management of the project and interpretation of results	contributed to the development of data collection tools, data collection, management of the project and interpretation of results	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Project administration|Resources	YES
5410623	28507556	All the authors	2	participated in data analysis and interpretation, and contributed to the writing and editing of the manuscript	participated in data analysis and interpretation, and contributed to the writing and editing of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5410623	28507556	KI	2	conceived the ideas for the study	conceived the ideas for the study	Conceived and designed the experiments	Conceptualization	YES
5410623	28507556	KM	2	conceived the ideas for the study|contributed to the experimentation	conceived the ideas for the study	Conceived and designed the experiments	Conceptualization	YES
5410623	28507556	KM	2	conceived the ideas for the study|contributed to the experimentation	contributed to the experimentation	Performed the experiments	Investigation	YES
5410623	28507556	ST	2	conceived the ideas for the study|contributed to the experimentation	conceived the ideas for the study	Conceived and designed the experiments	Conceptualization	YES
5410623	28507556	ST	2	conceived the ideas for the study|contributed to the experimentation	contributed to the experimentation	Performed the experiments	Investigation	YES
5410623	28507556	TH	2	contributed to the experimentation	contributed to the experimentation	Performed the experiments	Investigation	YES
2997084	21080919	BSP	2	developed the protocol, participated in drafting of the manuscript and interpretation of results	developed the protocol, participated in drafting of the manuscript and interpretation of results	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
2997084	21080919	ENK	2	participated in data collection	participated in data collection	Performed the experiments	Investigation	YES
2997084	21080919	LFS	2	participated in protocol development and interpretation of results	participated in protocol development and interpretation of results	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
2997084	21080919	MPM	2	drafted the manuscript, analyzed data and interpreted results	drafted the manuscript, analyzed data and interpreted results	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
2997084	21080919	MWM	2	participated in data collection	participated in data collection	Performed the experiments	Investigation	YES
2997084	21080919	MZC	2	supervised data collection	supervised data collection	Performed the experiments	Investigation|Supervision	YES
2997084	21080919	NS	2	participated in data collection	participated in data collection	Performed the experiments	Investigation	YES
2997084	21080919	RS	2	participated in data analysis	participated in data analysis	Analyzed the data	Formal analysis	YES
2997084	21080919	SJDV	2	contributed to drafting of the manuscript and interpretation of results	contributed to drafting of the manuscript and interpretation of results	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
2997084	21080919	SM	2	participated in data collection	participated in data collection	Performed the experiments	Investigation	YES
4979119	27506907	BBZ	2	participated in the preparation of plant materials and the design of this study and helped to draft the manuscript	participated in the preparation of plant materials and the design of this study and helped to draft the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
4979119	27506907	LW	2	participated in the data analysis of degradome library	participated in the data analysis of degradome library	Analyzed the data	Formal analysis	YES
4979119	27506907	QX	2	participated in the data analysis of degradome library	participated in the data analysis of degradome library	Analyzed the data	Formal analysis	YES
4979119	27506907	WWG	2	conceived and designed the research	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
4979119	27506907	XMW	2	participated in the preparation of plant materials and the design of this study and helped to draft the manuscript	participated in the preparation of plant materials and the design of this study and helped to draft the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
4979119	27506907	YNF	2	carried out the data analysis, performed the experiment and wrote the manuscript	carried out the data analysis, performed the experiment and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4383356	25866775	Arijit Bhowmik	2	wrote and analyzed the paper	wrote and analyzed the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4383356	25866775	Mrinal Kanti Ghosh	2	wrote and analyzed the paper	wrote and analyzed the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4383356	25866775	Rajni Khan	2	wrote and analyzed the paper	wrote and analyzed the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5547980	28933366	A.M.T.	2	also did some literature review and made corrections on the revised draft	also did some literature review and made corrections on the revised draft	Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5547980	28933366	H.A.	2	did extensive literature review and wrote most of the manuscript	did extensive literature review and wrote most of the manuscript	Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5547980	28933366	K.A.S.	2	did extensive literature review and wrote most of the manuscript	did extensive literature review and wrote most of the manuscript	Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5547980	28933366	M.A.	2	did extensive literature review and wrote most of the manuscript	did extensive literature review and wrote most of the manuscript	Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
4979122	27506390	AA	2	designed and performed the experiments|performed the genome assembly and annotation	designed and performed the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4979122	27506390	AA	2	designed and performed the experiments|performed the genome assembly and annotation	performed the genome assembly and annotation	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
4979122	27506390	AM	2	designed and performed the experiments	designed and performed the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4979122	27506390	ES	2	designed and performed the experiments|performed the genome assembly and annotation	designed and performed the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4979122	27506390	ES	2	designed and performed the experiments|performed the genome assembly and annotation	performed the genome assembly and annotation	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
4979122	27506390	FB	2	designed and performed the experiments	designed and performed the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4979122	27506390	FD	2	designed and performed the experiments	designed and performed the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4979122	27506390	GMcG	2	designed and performed the experiments|performed the genome assembly and annotation|wrote the manuscript with input from all authors	designed and performed the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4979122	27506390	GMcG	2	designed and performed the experiments|performed the genome assembly and annotation|wrote the manuscript with input from all authors	performed the genome assembly and annotation	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
4979122	27506390	GMcG	2	designed and performed the experiments|performed the genome assembly and annotation|wrote the manuscript with input from all authors	wrote the manuscript with input from all authors	Wrote the paper	Writing - Original Draft	YES
4979122	27506390	JJR	2	designed and performed the experiments	designed and performed the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4979122	27506390	JMF	2	designed and performed the experiments	designed and performed the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4979122	27506390	JMT	2	designed and performed the experiments	designed and performed the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4979122	27506390	KG	2	designed and performed the experiments	designed and performed the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4979122	27506390	KHK	2	designed and performed the experiments	designed and performed the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4979122	27506390	KK	2	designed and performed the experiments	designed and performed the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4979122	27506390	LJP	2	designed and performed the experiments	designed and performed the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4979122	27506390	MB	2	designed and performed the experiments	designed and performed the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4979122	27506390	MK	2	designed and performed the experiments	designed and performed the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4979122	27506390	NDH	2	designed and performed the experiments	designed and performed the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4979122	27506390	UT	2	designed and performed the experiments|performed the genome assembly and annotation	designed and performed the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4979122	27506390	UT	2	designed and performed the experiments|performed the genome assembly and annotation	performed the genome assembly and annotation	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5042906	28330283	The other authors	2	read, reviewed and provided feedback on the final manuscript	read, reviewed and provided feedback on the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5042906	28330283	Vo Van Giau	2	collected the samples, performed the experiments, analyzed and interpreted the data and wrote the manuscript	collected the samples, performed the experiments, analyzed and interpreted the data and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5410667	28507554	AC	2	conceived the experiment and designed the greenhouse and growth chamber experiment|designed the sequencing experiments|grew and dissected the plants, made physiological measurements and extracted rna|performed rt-qpcr experiments	conceived the experiment and designed the greenhouse and growth chamber experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5410667	28507554	AC	2	conceived the experiment and designed the greenhouse and growth chamber experiment|designed the sequencing experiments|grew and dissected the plants, made physiological measurements and extracted rna|performed rt-qpcr experiments	designed the sequencing experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5410667	28507554	AC	2	conceived the experiment and designed the greenhouse and growth chamber experiment|designed the sequencing experiments|grew and dissected the plants, made physiological measurements and extracted rna|performed rt-qpcr experiments	grew and dissected the plants, made physiological measurements and extracted rna	Performed the experiments	Investigation	YES
5410667	28507554	AC	2	conceived the experiment and designed the greenhouse and growth chamber experiment|designed the sequencing experiments|grew and dissected the plants, made physiological measurements and extracted rna|performed rt-qpcr experiments	performed rt-qpcr experiments	Performed the experiments	Investigation	YES
5410667	28507554	BC	2	designed the sequencing experiments|analyzed rna seq data	designed the sequencing experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5410667	28507554	BC	2	designed the sequencing experiments|analyzed rna seq data	analyzed rna seq data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5410667	28507554	CC	2	designed the sequencing experiments|grew and dissected the plants, made physiological measurements and extracted rna|analyzed rna seq data|performed rt-qpcr experiments	designed the sequencing experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5410667	28507554	CC	2	designed the sequencing experiments|grew and dissected the plants, made physiological measurements and extracted rna|analyzed rna seq data|performed rt-qpcr experiments	grew and dissected the plants, made physiological measurements and extracted rna	Performed the experiments	Investigation	YES
5410667	28507554	CC	2	designed the sequencing experiments|grew and dissected the plants, made physiological measurements and extracted rna|analyzed rna seq data|performed rt-qpcr experiments	analyzed rna seq data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5410667	28507554	CC	2	designed the sequencing experiments|grew and dissected the plants, made physiological measurements and extracted rna|analyzed rna seq data|performed rt-qpcr experiments	performed rt-qpcr experiments	Performed the experiments	Investigation	YES
5410667	28507554	EI	2	conceived the experiment and designed the greenhouse and growth chamber experiment	conceived the experiment and designed the greenhouse and growth chamber experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5410667	28507554	MJG	2	analyzed rna seq data	analyzed rna seq data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5410667	28507554	MPG	2	conceived the experiment and designed the greenhouse and growth chamber experiment	conceived the experiment and designed the greenhouse and growth chamber experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5547982	28933368	All authors	2	were involved in the preparation of the draft manuscript and have read, critically reviewed and approved the final version of the manuscript	were involved in the preparation of the draft manuscript and have read, critically reviewed and approved the final version of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5547982	28933368	Each author	2	conducts the research in their area of expertise	conducts the research in their area of expertise	Performed the experiments	Investigation	YES
4979126	27506195	GS	2	drafted the manuscript which was approved by all authors	drafted the manuscript which was approved by all authors	Wrote the paper	Writing - Original Draft	YES
4979126	27506195	MS-D	2	conceived and coordinated the study|drafted the manuscript which was approved by all authors	conceived and coordinated the study	Conceived and designed the experiments	Conceptualization|Project administration	YES
4979126	27506195	MS-D	2	conceived and coordinated the study|drafted the manuscript which was approved by all authors	drafted the manuscript which was approved by all authors	Wrote the paper	Writing - Original Draft	YES
5548228	28943604	Both authors	2	have contributed equally to subsequent editing	have contributed equally to subsequent editing	Wrote the paper	Writing - Review & Editing	YES
5548228	28943604	PEARS	2	operation in 2004 and the majority of subsequent operations and has led on clinical development	operation in 2004 and the majority of subsequent operations and has led on clinical development	Performed the experiments	Investigation	YES
5548228	28943604	Tom Treasure	2	developed the concept from 2000 and has led on analysis and dissemination and provided the first draft	developed the concept from 2000 and has led on analysis and dissemination and provided the first draft	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5411443	28512461	APa	2	conducted defoliation experiments, sampled the material and processed the data	conducted defoliation experiments, sampled the material and processed the data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5411443	28512461	APi	2	conducted defoliation experiments, sampled the material and processed the data	conducted defoliation experiments, sampled the material and processed the data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5411443	28512461	All authors	2	contributed to the revision of the manuscript	contributed to the revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5411443	28512461	CP	2	conducted defoliation experiments, sampled the material and processed the data|performed the hplc analysis	conducted defoliation experiments, sampled the material and processed the data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5411443	28512461	CP	2	conducted defoliation experiments, sampled the material and processed the data|performed the hplc analysis	performed the hplc analysis	Performed the experiments	Investigation	YES
5411443	28512461	ED	2	performed the rna extraction, microarray experiments, and real-time qpcr analysis	performed the rna extraction, microarray experiments, and real-time qpcr analysis	Performed the experiments	Investigation	YES
5411443	28512461	GA	2	conducted defoliation experiments, sampled the material and processed the data|performed the hplc analysis	conducted defoliation experiments, sampled the material and processed the data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5411443	28512461	GA	2	conducted defoliation experiments, sampled the material and processed the data|performed the hplc analysis	performed the hplc analysis	Performed the experiments	Investigation	YES
5411443	28512461	GBT	2	interpreted the microarray data and helped in drafting the manuscript	interpreted the microarray data and helped in drafting the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5411443	28512461	IF	2	conducted defoliation experiments, sampled the material and processed the data	conducted defoliation experiments, sampled the material and processed the data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5411443	28512461	MG	2	conducted defoliation experiments, sampled the material and processed the data|performed the hplc analysis	conducted defoliation experiments, sampled the material and processed the data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5411443	28512461	MG	2	conducted defoliation experiments, sampled the material and processed the data|performed the hplc analysis	performed the hplc analysis	Performed the experiments	Investigation	YES
5411443	28512461	OS	2	conducted defoliation experiments, sampled the material and processed the data	conducted defoliation experiments, sampled the material and processed the data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5411443	28512461	RDL	2	conducted defoliation experiments, sampled the material and processed the data	conducted defoliation experiments, sampled the material and processed the data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5411443	28512461	SDS	2	performed the statistical analyses|interpreted the microarray data and helped in drafting the manuscript	performed the statistical analyses	Analyzed the data	Formal analysis	YES
5411443	28512461	SDS	2	performed the statistical analyses|interpreted the microarray data and helped in drafting the manuscript	interpreted the microarray data and helped in drafting the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5411443	28512461	SP	2	conceived and supervised the study, wrote and critically revised the manuscript	conceived and supervised the study, wrote and critically revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
5411443	28512461	ST	2	conducted defoliation experiments, sampled the material and processed the data	conducted defoliation experiments, sampled the material and processed the data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5411443	28512461	SZ	2	designed the microarray experiments, interpreted the micro array data, and wrote the manuscript	designed the microarray experiments, interpreted the micro array data, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5411443	28512461	VL	2	conducted defoliation experiments, sampled the material and processed the data	conducted defoliation experiments, sampled the material and processed the data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
4383362	25866811	Huaqing Wang	2	conceived the study and participated in its design and revised the paper	conceived the study and participated in its design and revised the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
4383362	25866811	Huilai Zhang	2	participated in patient recruitment	participated in patient recruitment	Performed the experiments	Investigation	YES
4383362	25866811	Jing Zhao	2	participated in patient recruitment	participated in patient recruitment	Performed the experiments	Investigation	YES
4383362	25866811	Shiyong Zhou	2	participated in patient recruitment	participated in patient recruitment	Performed the experiments	Investigation	YES
4383362	25866811	The authors	2	contribution is as follows	contribution is as follows	-	-	NO
4383362	25866811	Xianhuo Wang	2	contributed with the analysis of the findings and writing of the paper	contributed with the analysis of the findings and writing of the paper	Wrote the paper	Writing - Original Draft	YES
4383362	25866811	Zhao Yan	2	had made contribution to acquisition of data	had made contribution to acquisition of data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4383362	25866811	Zheng Song	2	participated in patient recruitment	participated in patient recruitment	Performed the experiments	Investigation	YES
4383362	25866811	Zhengzi Qian	2	contributed with the design and implementation of the study protocol	contributed with the design and implementation of the study protocol	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4979127	27506816	AK	2	carried out experiments in the laboratory	carried out experiments in the laboratory	Performed the experiments	Investigation	YES
4979127	27506816	AL	2	designed the experiments|carried out experiments in the laboratory	designed the experiments	Conceived and designed the experiments	Methodology	YES
4979127	27506816	AL	2	designed the experiments|carried out experiments in the laboratory	carried out experiments in the laboratory	Performed the experiments	Investigation	YES
4979127	27506816	All authors	2	commented on the manuscript and approved the final version	commented on the manuscript and approved the final version	-	-	NO
4979127	27506816	HKJ	2	designed the experiments|analyzed and interpreted the results|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
4979127	27506816	HKJ	2	designed the experiments|analyzed and interpreted the results|wrote the manuscript	analyzed and interpreted the results	Analyzed the data	Formal analysis	YES
4979127	27506816	HKJ	2	designed the experiments|analyzed and interpreted the results|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4979127	27506816	LMS	2	designed the experiments|carried out experiments in the laboratory|conducted the metagenome analysis|analyzed and interpreted the results|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
4979127	27506816	LMS	2	designed the experiments|carried out experiments in the laboratory|conducted the metagenome analysis|analyzed and interpreted the results|wrote the manuscript	carried out experiments in the laboratory	Performed the experiments	Investigation	YES
4979127	27506816	LMS	2	designed the experiments|carried out experiments in the laboratory|conducted the metagenome analysis|analyzed and interpreted the results|wrote the manuscript	conducted the metagenome analysis	Performed the experiments	Investigation	YES
4979127	27506816	LMS	2	designed the experiments|carried out experiments in the laboratory|conducted the metagenome analysis|analyzed and interpreted the results|wrote the manuscript	analyzed and interpreted the results	Analyzed the data	Formal analysis	YES
4979127	27506816	LMS	2	designed the experiments|carried out experiments in the laboratory|conducted the metagenome analysis|analyzed and interpreted the results|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4979127	27506816	RLM	2	designed the experiments|conducted the metagenome analysis|analyzed and interpreted the results	designed the experiments	Conceived and designed the experiments	Methodology	YES
4979127	27506816	RLM	2	designed the experiments|conducted the metagenome analysis|analyzed and interpreted the results	conducted the metagenome analysis	Performed the experiments	Investigation	YES
4979127	27506816	RLM	2	designed the experiments|conducted the metagenome analysis|analyzed and interpreted the results	analyzed and interpreted the results	Analyzed the data	Formal analysis	YES
4979127	27506816	SM	2	designed the experiments|analyzed and interpreted the results|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
4979127	27506816	SM	2	designed the experiments|analyzed and interpreted the results|wrote the manuscript	analyzed and interpreted the results	Analyzed the data	Formal analysis	YES
4979127	27506816	SM	2	designed the experiments|analyzed and interpreted the results|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5548230	28943606	F.A.	2	performed data collection, critically reviewed the manuscript and approved the final manuscript	performed data collection, critically reviewed the manuscript and approved the final manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5548230	28943606	G.C.M.	2	supervised data collection, performed initial analysis and critically reviewed and revised the manuscript and approved the final manuscript	supervised data collection, performed initial analysis and critically reviewed and revised the manuscript and approved the final manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Supervision|Writing - Review & Editing	YES
5548230	28943606	G.H.	2	coordinated and performed data collection, designed data collection instruments, critically reviewed the manuscript and approved the final manuscript	coordinated and performed data collection, designed data collection instruments, critically reviewed the manuscript and approved the final manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Project administration|Writing - Review & Editing	YES
5548230	28943606	K.J.S.	2	coordinated and performed data collection, designed data collection instruments, critically reviewed the manuscript and approved the final manuscript	coordinated and performed data collection, designed data collection instruments, critically reviewed the manuscript and approved the final manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Project administration|Writing - Review & Editing	YES
5548230	28943606	R.K.	2	reviewed and revised the manuscript and approved the final manuscript	reviewed and revised the manuscript and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5548230	28943606	T.S.M.	2	conceptualized the study, coordinated and supervised data collection, reviewed, revised and approved the final manuscript	conceptualized the study, coordinated and supervised data collection, reviewed, revised and approved the final manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Project administration|Supervision|Writing - Review & Editing	YES
5548230	28943606	V.C.S.	2	conceptualized the study, performed data collection, designed data collection instruments, performed initial analysis, drafted the initial manuscript and approved final manuscript	conceptualized the study, performed data collection, designed data collection instruments, performed initial analysis, drafted the initial manuscript and approved final manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5548230	28943606	Y.V.K.	2	reviewed and revised the manuscript and approved the final manuscript	reviewed and revised the manuscript and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
3002304	21108804	All authors	PLoS52	interpreted the data|contributed to the writing of the manuscript, and all authors approved the manuscript for publication	interpreted the data	Analyzed the data	Formal analysis	YES
3002304	21108804	All authors	PLoS52	interpreted the data|contributed to the writing of the manuscript, and all authors approved the manuscript for publication	contributed to the writing of the manuscript, and all authors approved the manuscript for publication	Wrote the paper	Writing - Original Draft	YES
3002304	21108804	BE	PLoS52	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
3002304	21108804	GF	PLoS52	designed the study|analyzed the data	designed the study	Conceived and designed the experiments	Methodology	YES
3002304	21108804	GF	PLoS52	designed the study|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
3002304	21108804	PB	PLoS52	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5411447	28512463	Hawaiian Commercial	4	Resources were provided by	Resources were provided by	Contributed reagents/materials/analysis tools	Resources	YES
5548231	28943605	ASL	2	contributed to the conception and design of the study, collection, analysis and interpretation of the data, the collection/generation of the figures and the drafting and critical revision of the article	contributed to the conception and design of the study, collection, analysis and interpretation of the data, the collection/generation of the figures and the drafting and critical revision of the article	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Resources|Visualization|Writing - Original Draft|Writing - Review & Editing	YES
5548231	28943605	All authors	2	gave final approval of the article	gave final approval of the article	-	-	NO
5548231	28943605	CDB	2	contributed to the conception and design of the study and the drafting and critical revision of the article	contributed to the conception and design of the study and the drafting and critical revision of the article	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5548231	28943605	JN	2	contributed to the experiments, collection, analysis and interpretation of the data	contributed to the experiments, collection, analysis and interpretation of the data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5548231	28943605	VK	2	contributed to the analysis, interpretation of the data and drafting and critical revision of the article	contributed to the analysis, interpretation of the data and drafting and critical revision of the article	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft|Writing - Review & Editing	YES
3004826	21129197	Both authors	2	contributed to the research and writing of this paper, and read and approved the final manuscript	contributed to the research and writing of this paper, and read and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4979139	27507140	All authors	2	contributed to drafting, and read and approved the final manuscript	contributed to drafting, and read and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4979139	27507140	BP	2	were involved in the design of the study, data analysis and interpretation	were involved in the design of the study, data analysis and interpretation	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
4979139	27507140	CH	2	contributed to data acquisition and analysis	contributed to data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4979139	27507140	IL	2	performed bioinformatics analysis	performed bioinformatics analysis	Performed the experiments	Formal analysis|Investigation	YES
4979139	27507140	JF	2	were involved in the design of the study, data analysis and interpretation|wrote the manuscript	were involved in the design of the study, data analysis and interpretation	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
4979139	27507140	JF	2	were involved in the design of the study, data analysis and interpretation|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4979139	27507140	JMG	2	were involved in the design of the study, data analysis and interpretation|conceived the study	were involved in the design of the study, data analysis and interpretation	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
4979139	27507140	JMG	2	were involved in the design of the study, data analysis and interpretation|conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4979139	27507140	RV	2	were involved in the design of the study, data analysis and interpretation	were involved in the design of the study, data analysis and interpretation	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
4383387	25866802	Chanjiao Zheng	PLoS52	conceived and designed the research|were responsible for literature searching and data extraction|wrote the paper|contributed equally to this paper	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
4383387	25866802	Chanjiao Zheng	PLoS52	conceived and designed the research|were responsible for literature searching and data extraction|wrote the paper|contributed equally to this paper	were responsible for literature searching and data extraction	Analyzed the data	Data curation|Formal analysis	YES
4383387	25866802	Chanjiao Zheng	PLoS52	conceived and designed the research|were responsible for literature searching and data extraction|wrote the paper|contributed equally to this paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4383387	25866802	Chanjiao Zheng	PLoS52	conceived and designed the research|were responsible for literature searching and data extraction|wrote the paper|contributed equally to this paper	contributed equally to this paper	-	-	NO
4383387	25866802	Huanyu Shen	PLoS52	were responsible for literature searching and data extraction|contributed equally to this paper	were responsible for literature searching and data extraction	Analyzed the data	Data curation|Formal analysis	YES
4383387	25866802	Huanyu Shen	PLoS52	were responsible for literature searching and data extraction|contributed equally to this paper	contributed equally to this paper	-	-	NO
4383387	25866802	Jiaji Wang	PLoS52	were responsible for the quality assessment of studies	were responsible for the quality assessment of studies	-	Validation	YES
4383387	25866802	Weilin Ou	PLoS52	were responsible for literature searching and data extraction|were responsible for the quality assessment of studies|contributed equally to this paper	were responsible for literature searching and data extraction	Analyzed the data	Data curation|Formal analysis	YES
4383387	25866802	Weilin Ou	PLoS52	were responsible for literature searching and data extraction|were responsible for the quality assessment of studies|contributed equally to this paper	were responsible for the quality assessment of studies	-	Validation	YES
4383387	25866802	Weilin Ou	PLoS52	were responsible for literature searching and data extraction|were responsible for the quality assessment of studies|contributed equally to this paper	contributed equally to this paper	-	-	NO
4383387	25866802	Zhiheng Zhou	PLoS52	conceived and designed the research|wrote the paper	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
4383387	25866802	Zhiheng Zhou	PLoS52	conceived and designed the research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3004827	21134284	BRP	2	participated in the adherence exercise, data gathering, and initial manuscript development	participated in the adherence exercise, data gathering, and initial manuscript development	-	-	NO
3004827	21134284	SJH	2	participated in the adherence exercise, data gathering, and initial manuscript development	participated in the adherence exercise, data gathering, and initial manuscript development	-	-	NO
5411758	28512464	All authors	PLoS52	discussed the results and commented on the manuscript	discussed the results and commented on the manuscript	-	-	NO
5411758	28512464	HMW	PLoS52	wrote the paper|performed experiments|performed the statistical analyses|are involved in field management and soil sampling	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5411758	28512464	HMW	PLoS52	wrote the paper|performed experiments|performed the statistical analyses|are involved in field management and soil sampling	performed experiments	Performed the experiments	Investigation	YES
5411758	28512464	HMW	PLoS52	wrote the paper|performed experiments|performed the statistical analyses|are involved in field management and soil sampling	performed the statistical analyses	Analyzed the data	Formal analysis	YES
5411758	28512464	HMW	PLoS52	wrote the paper|performed experiments|performed the statistical analyses|are involved in field management and soil sampling	are involved in field management and soil sampling	Performed the experiments	Investigation	YES
5411758	28512464	HW	PLoS52	conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5411758	28512464	JW	PLoS52	performed experiments|have revised the manuscript	performed experiments	Performed the experiments	Investigation	YES
5411758	28512464	JW	PLoS52	performed experiments|have revised the manuscript	have revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5411758	28512464	JX	PLoS52	have revised the manuscript	have revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5411758	28512464	LW	PLoS52	performed the statistical analyses	performed the statistical analyses	Analyzed the data	Formal analysis	YES
5411758	28512464	MK	PLoS52	wrote the paper|have revised the manuscript	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5411758	28512464	MK	PLoS52	wrote the paper|have revised the manuscript	have revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5411758	28512464	QZ	PLoS52	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5411758	28512464	SL	PLoS52	performed the statistical analyses|are involved in field management and soil sampling	performed the statistical analyses	Analyzed the data	Formal analysis	YES
5411758	28512464	SL	PLoS52	performed the statistical analyses|are involved in field management and soil sampling	are involved in field management and soil sampling	Performed the experiments	Investigation	YES
5411758	28512464	WWL	PLoS52	are involved in field management and soil sampling	are involved in field management and soil sampling	Performed the experiments	Investigation	YES
5411758	28512464	WXL	PLoS52	conceived the study|wrote the paper	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5411758	28512464	WXL	PLoS52	conceived the study|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5411758	28512464	XQ	PLoS52	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5411758	28512464	ZL	PLoS52	performed experiments	performed experiments	Performed the experiments	Investigation	YES
4979143	27507242	AF	PLoS5	Performed research|Analysis and interpretation of data|Wrote the paper	Performed research	Performed the experiments	Investigation	YES
4979143	27507242	AF	PLoS5	Performed research|Analysis and interpretation of data|Wrote the paper	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
4979143	27507242	AF	PLoS5	Performed research|Analysis and interpretation of data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4979143	27507242	GE	PLoS5	Performed research|Wrote the paper	Performed research	Performed the experiments	Investigation	YES
4979143	27507242	GE	PLoS5	Performed research|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4979143	27507242	LPF	PLoS5	Performed research|Analysis and interpretation of data|Wrote the paper	Performed research	Performed the experiments	Investigation	YES
4979143	27507242	LPF	PLoS5	Performed research|Analysis and interpretation of data|Wrote the paper	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
4979143	27507242	LPF	PLoS5	Performed research|Analysis and interpretation of data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4979143	27507242	MLMH	PLoS5	Performed research|Analysis and interpretation of data|Wrote the paper	Performed research	Performed the experiments	Investigation	YES
4979143	27507242	MLMH	PLoS5	Performed research|Analysis and interpretation of data|Wrote the paper	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
4979143	27507242	MLMH	PLoS5	Performed research|Analysis and interpretation of data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4979143	27507242	TB	PLoS5	Conception and design of the experiments|Analysis and interpretation of data|Wrote the paper	Conception and design of the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4979143	27507242	TB	PLoS5	Conception and design of the experiments|Analysis and interpretation of data|Wrote the paper	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
4979143	27507242	TB	PLoS5	Conception and design of the experiments|Analysis and interpretation of data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3012655	21134297	AB	2	contributed to the study concept and design and to analysis and interpretation of the data, in addition to drafting and critical revision of the manuscript for important intellectual content	contributed to the study concept and design and to analysis and interpretation of the data, in addition to drafting and critical revision of the manuscript for important intellectual content	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
3012655	21134297	IS	2	contributed to the acquisition of data, provided critical revision of the manuscript and obtained funding	contributed to the acquisition of data, provided critical revision of the manuscript and obtained funding	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Funding acquisition|Investigation|Resources|Writing - Review & Editing	YES
3012655	21134297	MF	2	contributed to the study concept and design and to analysis and interpretation of the data, in addition to drafting and critical revision of the manuscript for important intellectual content	contributed to the study concept and design and to analysis and interpretation of the data, in addition to drafting and critical revision of the manuscript for important intellectual content	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
3012655	21134297	MM	2	contributed to the analysis and interpretation of the data and critical revision of the manuscript	contributed to the analysis and interpretation of the data and critical revision of the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
5548234	28943609	All authors	2	treated patients and gave final approval of the article	treated patients and gave final approval of the article	Performed the experiments	Investigation	YES
5548234	28943609	S.N.	2	collected the data	collected the data	Performed the experiments	Investigation	YES
5548234	28943609	T.M.	2	supervised the study and edited the manuscript	supervised the study and edited the manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
5548234	28943609	T.O.	2	designed the study, analyzed and interpreted the data and wrote the manuscript|collected the data	designed the study, analyzed and interpreted the data and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5548234	28943609	T.O.	2	designed the study, analyzed and interpreted the data and wrote the manuscript|collected the data	collected the data	Performed the experiments	Investigation	YES
5548234	28943609	Y.E.	2	supervised the study and edited the manuscript	supervised the study and edited the manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
3014874	21143929	CD	4	drafted and authored by	drafted and authored by	Wrote the paper	Writing - Original Draft	YES
4979145	27506765	All authors	PLoS52	read, edited and approved the final manuscript	read, edited and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4979145	27506765	CJ	PLoS52	conceived and designed the study|analyzed the data|contributed the materials	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4979145	27506765	CJ	PLoS52	conceived and designed the study|analyzed the data|contributed the materials	analyzed the data	Analyzed the data	Formal analysis	YES
4979145	27506765	CJ	PLoS52	conceived and designed the study|analyzed the data|contributed the materials	contributed the materials	Contributed reagents/materials/analysis tools	Resources	YES
4979145	27506765	DZ	PLoS52	conceived and designed the study|contributed the materials	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4979145	27506765	DZ	PLoS52	conceived and designed the study|contributed the materials	contributed the materials	Contributed reagents/materials/analysis tools	Resources	YES
4979145	27506765	JX	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
4979145	27506765	QN	PLoS52	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4979145	27506765	XZ	PLoS52	conceived and designed the study|supervised the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4979145	27506765	XZ	PLoS52	conceived and designed the study|supervised the study	supervised the study	-	Supervision	YES
4979145	27506765	YZ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
4979145	27506765	ZX	PLoS52	conceived and designed the study|performed the experiments|analyzed the data|wrote the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4979145	27506765	ZX	PLoS52	conceived and designed the study|performed the experiments|analyzed the data|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
4979145	27506765	ZX	PLoS52	conceived and designed the study|performed the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
4979145	27506765	ZX	PLoS52	conceived and designed the study|performed the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4979145	27506765	ZZ	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5411819	28512466	EG	2	conducted the experiments	conducted the experiments	Performed the experiments	Investigation	YES
5411819	28512466	NB	2	developed the project, analyzed the results, and wrote the manuscript	developed the project, analyzed the results, and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5411819	28512466	ND	2	regulated the essential oils analyses	regulated the essential oils analyses	Analyzed the data	Formal analysis	YES
5411819	28512466	SS	2	regulated the microbiological analyses	regulated the microbiological analyses	Analyzed the data	Formal analysis	YES
3017012	21144037	CASK	2	participated in interpretation and the drafting on the manuscript	participated in interpretation and the drafting on the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3017012	21144037	GN	2	participated in the design of the study, interpretation and drafting of the manuscript	participated in the design of the study, interpretation and drafting of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3017012	21144037	JKT	2	participated in the design, and implementation of the study, interpretation and drafting of the manuscript	participated in the design, and implementation of the study, interpretation and drafting of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
3017012	21144037	RB	2	participated in the conception, design and implementation of the study, statistical analysis, interpretation and drafting of the manuscript	participated in the conception, design and implementation of the study, statistical analysis, interpretation and drafting of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
3017012	21144037	TT	2	participated in the conception and design of the study, interpretation and drafting the manuscript	participated in the conception and design of the study, interpretation and drafting the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
4383400	25866806	Igor Pottosin	2	had an equal contribution	had an equal contribution	-	-	NO
4383400	25866806	Oxana Dobrovinskaya	2	had an equal contribution	had an equal contribution	-	-	NO
4979156	27506777	AH	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4979156	27506777	EL	2	designed the study|performed the analyses|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
4979156	27506777	EL	2	designed the study|performed the analyses|wrote the manuscript	performed the analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4979156	27506777	EL	2	designed the study|performed the analyses|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4979156	27506777	LG	2	performed the analyses	performed the analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5412092	28512462	JKe	2	conception and design of the experiment, plant and rna sample preparation	conception and design of the experiment, plant and rna sample preparation	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
5412092	28512462	JKo	2	conception of the experiment and interpretation of data for the work	conception of the experiment and interpretation of data for the work	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation	YES
5412092	28512462	KM	2	conception and design of the experiment, plant and rna sample preparation	conception and design of the experiment, plant and rna sample preparation	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
5412092	28512462	NK	2	conception and design of the experiment, plant and rna sample preparation	conception and design of the experiment, plant and rna sample preparation	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
5412092	28512462	PG	2	conception and design of the experiment, plant and rna sample preparation, data analysis, interpretation of data and wrote the manuscript	conception and design of the experiment, plant and rna sample preparation, data analysis, interpretation of data and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5412092	28512462	WG	2	mk data analysis and manuscript preparation	mk data analysis and manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5412092	28512462	WW	2	conception and design of the experiment, plant and rna sample preparation	conception and design of the experiment, plant and rna sample preparation	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
3019126	21143940	AG	2	designed the current study concept	designed the current study concept	Conceived and designed the experiments	Conceptualization|Methodology	YES
3019126	21143940	KP	2	designed the current study concept|conducted the statistical analyses and drafted the manuscript	designed the current study concept	Conceived and designed the experiments	Conceptualization|Methodology	YES
3019126	21143940	KP	2	designed the current study concept|conducted the statistical analyses and drafted the manuscript	conducted the statistical analyses and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3019126	21143940	ML	2	designed the current study concept	designed the current study concept	Conceived and designed the experiments	Conceptualization|Methodology	YES
3027084	21208405	All authors	2	contributed considerably to the intellectual content of this article	contributed considerably to the intellectual content of this article	-	-	NO
3027084	21208405	BM	2	authorized the interventions	authorized the interventions	-	-	NO
3027084	21208405	HC	2	authorized the interventions	authorized the interventions	-	-	NO
3027084	21208405	KH	2	checked scientific soundness and reviewed the manuscript several times|finalized the manuscript	checked scientific soundness and reviewed the manuscript several times	Wrote the paper	Writing - Review & Editing	YES
3027084	21208405	KH	2	checked scientific soundness and reviewed the manuscript several times|finalized the manuscript	finalized the manuscript	Wrote the paper	Writing - Review & Editing	YES
3027084	21208405	MB	2	conceptualized the study and wrote a first draft, which was edited by all other authors|authorized the interventions|finalized the manuscript	conceptualized the study and wrote a first draft, which was edited by all other authors	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
3027084	21208405	MB	2	conceptualized the study and wrote a first draft, which was edited by all other authors|authorized the interventions|finalized the manuscript	authorized the interventions	-	-	NO
3027084	21208405	MB	2	conceptualized the study and wrote a first draft, which was edited by all other authors|authorized the interventions|finalized the manuscript	finalized the manuscript	Wrote the paper	Writing - Review & Editing	YES
3027084	21208405	MP	2	finalized the manuscript	finalized the manuscript	Wrote the paper	Writing - Review & Editing	YES
3027084	21208405	NF	2	checked scientific soundness and reviewed the manuscript several times|finalized the manuscript	checked scientific soundness and reviewed the manuscript several times	Wrote the paper	Writing - Review & Editing	YES
3027084	21208405	NF	2	checked scientific soundness and reviewed the manuscript several times|finalized the manuscript	finalized the manuscript	Wrote the paper	Writing - Review & Editing	YES
3027084	21208405	NST	2	assisted with data collection	assisted with data collection	Performed the experiments	Investigation	YES
3027084	21208405	OP	2	assisted with data collection	assisted with data collection	Performed the experiments	Investigation	YES
3027084	21208405	TvdA	2	conceptualized the study and wrote a first draft, which was edited by all other authors|assisted with data collection|finalized the manuscript	conceptualized the study and wrote a first draft, which was edited by all other authors	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
3027084	21208405	TvdA	2	conceptualized the study and wrote a first draft, which was edited by all other authors|assisted with data collection|finalized the manuscript	assisted with data collection	Performed the experiments	Investigation	YES
3027084	21208405	TvdA	2	conceptualized the study and wrote a first draft, which was edited by all other authors|assisted with data collection|finalized the manuscript	finalized the manuscript	Wrote the paper	Writing - Review & Editing	YES
3027084	21208405	WJ	2	assisted with data collection	assisted with data collection	Performed the experiments	Investigation	YES
5548236	28943613	A.V.	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5548236	28943613	C.M.	2	completely wrote the manuscript	completely wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5548236	28943613	M.B.	2	completely wrote the manuscript	completely wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4979158	27507266	AM	2	performed the analyses and drafted the manuscript	performed the analyses and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4979158	27507266	DG	2	performed part of the analyses and drafted the manuscript	performed part of the analyses and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4979158	27507266	DTS	2	assisted with analytical recommendations and drafting the manuscript	assisted with analytical recommendations and drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
4979158	27507266	SB	2	conceived the study, participated in its design and coordination and drafted the manuscript	conceived the study, participated in its design and coordination and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
5412260	28512465	HZ	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5412260	28512465	JL	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5412260	28512465	MH	PLoS52	wrote the main manuscript	wrote the main manuscript	Wrote the paper	Writing - Original Draft	YES
5412260	28512465	QJ	PLoS52	gave the valuable guidance for the experiments	gave the valuable guidance for the experiments	-	Supervision	YES
5412260	28512465	XL	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5412260	28512465	YG	PLoS52	helped to modify the manuscript	helped to modify the manuscript	Wrote the paper	Writing - Review & Editing	YES
3027085	21219607	AM	2	contributed to the design of the study, interpretation of results, and critical revision of the manuscript	contributed to the design of the study, interpretation of results, and critical revision of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
3027085	21219607	CU	2	assisted with the study in the field, and contributed to the interpretations of results	assisted with the study in the field, and contributed to the interpretations of results	Analyzed the data	Formal analysis	YES
3027085	21219607	DMO	2	contributed to the design of the study, interpretation of results, and critical revision of the manuscript	contributed to the design of the study, interpretation of results, and critical revision of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
3027085	21219607	ES	2	contributed to the design of the study, interpretation of results, and critical revision of the manuscript	contributed to the design of the study, interpretation of results, and critical revision of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
3027085	21219607	HH	2	assisted with the study in the field, and contributed to the interpretations of results	assisted with the study in the field, and contributed to the interpretations of results	Analyzed the data	Formal analysis	YES
3027085	21219607	LA	2	designed the study, analyzed and managed data, interpreted results, and wrote the manuscript	designed the study, analyzed and managed data, interpreted results, and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Data curation|Formal analysis|Methodology|Writing - Original Draft	YES
3027085	21219607	MPR	2	designed the study, analyzed and managed data, interpreted results, and wrote the manuscript	designed the study, analyzed and managed data, interpreted results, and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Data curation|Formal analysis|Methodology|Writing - Original Draft	YES
3027085	21219607	SB	2	contributed to the design of the study, interpretation of results, and critical revision of the manuscript	contributed to the design of the study, interpretation of results, and critical revision of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
3027085	21219607	SN	2	contributed to data management and analyses	contributed to data management and analyses	Analyzed the data	Data curation|Formal analysis	YES
4979166	27506469	HBS	2	designed the study and drafted the manuscript	designed the study and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4979166	27506469	JY	2	participated in its design	participated in its design	Conceived and designed the experiments	-	YES
4979166	27506469	XP	2	designed the study and drafted the manuscript|did the bioinformatics analysis	designed the study and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4979166	27506469	XP	2	designed the study and drafted the manuscript|did the bioinformatics analysis	did the bioinformatics analysis	-	Formal analysis	YES
4979166	27506469	YXF	2	did the bioinformatics analysis	did the bioinformatics analysis	-	Formal analysis	YES
3037294	21251327	ANK	2	participated in the design of the study and performed the statistical analysis	participated in the design of the study and performed the statistical analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
3037294	21251327	BC	2	participated in its design and coordination, and provided comments on the manuscript	participated in its design and coordination, and provided comments on the manuscript	Conceived and designed the experiments	Project administration	YES
3037294	21251327	PS	2	participated in its design and coordination, and provided comments on the manuscript	participated in its design and coordination, and provided comments on the manuscript	Conceived and designed the experiments	Project administration	YES
3037294	21251327	TM	2	participated in its design and coordination, and provided comments on the manuscript	participated in its design and coordination, and provided comments on the manuscript	Conceived and designed the experiments	Project administration	YES
4979184	27506621	FDC	PLoS52	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
4979184	27506621	FJZ	PLoS52	designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
4979184	27506621	FJZ	PLoS52	designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
4979184	27506621	FJZ	PLoS52	designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
4979184	27506621	FJZ	PLoS52	designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4979184	27506621	FW	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
4979184	27506621	JSF	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
4979184	27506621	LCH	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
4979184	27506621	LCH	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
4979184	27506621	NJT	PLoS52	designed the experiments|analyzed the data|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
4979184	27506621	NJT	PLoS52	designed the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
4979184	27506621	NJT	PLoS52	designed the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4979184	27506621	WMF	PLoS52	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
4979184	27506621	YL	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5413499	28515733	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5413499	28515733	GW	2	collected the tissue material and performed the experiments	collected the tissue material and performed the experiments	Performed the experiments	Investigation	YES
5413499	28515733	HT	2	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5413499	28515733	JC	2	performed data analysis	performed data analysis	Analyzed the data	Formal analysis	YES
5413499	28515733	JY	2	collected the tissue material and performed the experiments	collected the tissue material and performed the experiments	Performed the experiments	Investigation	YES
5413499	28515733	LZ	2	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5413499	28515733	QZ	2	performed data analysis	performed data analysis	Analyzed the data	Formal analysis	YES
5413499	28515733	YC	2	collected the tissue material and performed the experiments	collected the tissue material and performed the experiments	Performed the experiments	Investigation	YES
5413499	28515733	YD	2	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5413499	28515733	YH	2	conceived and designed the study|collected the tissue material and performed the experiments|performed data analysis|wrote the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5413499	28515733	YH	2	conceived and designed the study|collected the tissue material and performed the experiments|performed data analysis|wrote the manuscript	collected the tissue material and performed the experiments	Performed the experiments	Investigation	YES
5413499	28515733	YH	2	conceived and designed the study|collected the tissue material and performed the experiments|performed data analysis|wrote the manuscript	performed data analysis	Analyzed the data	Formal analysis	YES
5413499	28515733	YH	2	conceived and designed the study|collected the tissue material and performed the experiments|performed data analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5413499	28515733	ZG	2	performed data analysis	performed data analysis	Analyzed the data	Formal analysis	YES
5548239	28943610	Janalee Heinemann	7	Editing and assistance with manuscript preparation	Editing and assistance with manuscript preparation	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5548239	28943610	Jennifer Miller	7	Primary author - wrote the manuscript	Primary author - wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5548239	28943610	Theresa Strong	7	Editing and assistance with manuscript preparation	Editing and assistance with manuscript preparation	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3037295	21255462	BS	2	reviewed the manuscript and provided helpful comments	reviewed the manuscript and provided helpful comments	Wrote the paper	Writing - Review & Editing	YES
3037295	21255462	JHE	2	reviewed the manuscript and provided helpful comments	reviewed the manuscript and provided helpful comments	Wrote the paper	Writing - Review & Editing	YES
3037295	21255462	NC	2	reviewed the manuscript and provided helpful comments	reviewed the manuscript and provided helpful comments	Wrote the paper	Writing - Review & Editing	YES
3037295	21255462	SRL	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3037295	21255462	VAE	2	prepared the figure and table and contributed to the critical revision of the manuscript	prepared the figure and table and contributed to the critical revision of the manuscript	Wrote the paper	Visualization|Writing - Original Draft|Writing - Review & Editing	YES
4979188	27506833	KJ	2	analysed data|drafted the manuscript	analysed data	Analyzed the data	Formal analysis	YES
4979188	27506833	KJ	2	analysed data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4979188	27506833	YX	2	conceived and designed the study|analysed data|drafted the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4979188	27506833	YX	2	conceived and designed the study|analysed data|drafted the manuscript	analysed data	Analyzed the data	Formal analysis	YES
4979188	27506833	YX	2	conceived and designed the study|analysed data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4979188	27506833	ZW	2	prepared the rna samples for rna seq and performed the qpcrs|analysed data|drafted the manuscript	prepared the rna samples for rna seq and performed the qpcrs	Performed the experiments	Investigation	YES
4979188	27506833	ZW	2	prepared the rna samples for rna seq and performed the qpcrs|analysed data|drafted the manuscript	analysed data	Analyzed the data	Formal analysis	YES
4979188	27506833	ZW	2	prepared the rna samples for rna seq and performed the qpcrs|analysed data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
3037296	21261982	AAG	2	helped to draft the manuscript and participated in its design coordination	helped to draft the manuscript and participated in its design coordination	Conceived and designed the experiments|Wrote the paper	Project administration|Writing - Original Draft	YES
3037296	21261982	FCL	2	drafted the manuscript and conceived the outline	drafted the manuscript and conceived the outline	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
3037296	21261982	JAR	2	provided patient samples, photographs, helped to draft the manuscript and gave insightful comments	provided patient samples, photographs, helped to draft the manuscript and gave insightful comments	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Visualization|Writing - Original Draft	YES
3037296	21261982	JRT	2	conceived the outline, helped draft the manuscript and coordinated its design	conceived the outline, helped draft the manuscript and coordinated its design	Conceived and designed the experiments|Wrote the paper	Conceptualization|Project administration|Writing - Original Draft	YES
3037296	21261982	MGF	2	provided patient samples, photographs, helped to draft the manuscript and gave insightful comments	provided patient samples, photographs, helped to draft the manuscript and gave insightful comments	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Visualization|Writing - Original Draft	YES
3037296	21261982	NM	2	provided patient samples, photographs, helped to draft the manuscript and gave insightful comments	provided patient samples, photographs, helped to draft the manuscript and gave insightful comments	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Visualization|Writing - Original Draft	YES
5413500	28515732	CM	2	gave many advices during the research	gave many advices during the research	-	-	NO
5413500	28515732	LZ	2	designed and conduct the trial, and drafted and revised the manuscript, they two have the equal contribution on the article	designed and conduct the trial, and drafted and revised the manuscript, they two have the equal contribution on the article	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5413500	28515732	MZ	2	took part in the experiment	took part in the experiment	-	-	NO
5413500	28515732	QC	2	took part in the experiment	took part in the experiment	-	-	NO
5413500	28515732	TL	2	gave many advices during the research|provide financial support for the study	gave many advices during the research	-	-	NO
5413500	28515732	TL	2	gave many advices during the research|provide financial support for the study	provide financial support for the study	-	Funding acquisition	YES
5413500	28515732	WL	2	gave many advices during the research	gave many advices during the research	-	-	NO
5413500	28515732	XY	2	took part in the experiment	took part in the experiment	-	-	NO
5413500	28515732	YN	2	took part in the experiment	took part in the experiment	-	-	NO
5413500	28515732	YR	2	gave many advices during the research	gave many advices during the research	-	-	NO
5413500	28515732	ZL	2	took part in the experiment	took part in the experiment	-	-	NO
5413500	28515732	ZW	2	gave many advices during the research	gave many advices during the research	-	-	NO
5413500	28515732	ZX	2	designed and conduct the trial, and drafted and revised the manuscript, they two have the equal contribution on the article	designed and conduct the trial, and drafted and revised the manuscript, they two have the equal contribution on the article	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
3042896	21294916	DM	2	were involved with data interpretation and writing the paper	were involved with data interpretation and writing the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3042896	21294916	EJB	2	conceived the study, were involved with the design, data collection, analyses and writing the paper	conceived the study, were involved with the design, data collection, analyses and writing the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
3042896	21294916	GH	2	was involved with the design of the study, data collection, analyses and writing the paper	was involved with the design of the study, data collection, analyses and writing the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
3042896	21294916	PDL	2	were involved with data interpretation and writing the paper	were involved with data interpretation and writing the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3042896	21294916	SM	2	was involved with the design of the study, analyses and writing the paper	was involved with the design of the study, analyses and writing the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3042896	21294916	XS	2	conceived the study, were involved with the design, data collection, analyses and writing the paper	conceived the study, were involved with the design, data collection, analyses and writing the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4979189	27506932	DS	2	performed the analyses	performed the analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4979189	27506932	MS	2	conceived and designed the study|performed the analyses|wrote the manuscript with the	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4979189	27506932	MS	2	conceived and designed the study|performed the analyses|wrote the manuscript with the	performed the analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4979189	27506932	MS	2	conceived and designed the study|performed the analyses|wrote the manuscript with the	wrote the manuscript with the	Wrote the paper	Writing - Original Draft	YES
4979189	27506932	MY	2	conceived and designed the study|performed the analyses|wrote the manuscript with the	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4979189	27506932	MY	2	conceived and designed the study|performed the analyses|wrote the manuscript with the	performed the analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4979189	27506932	MY	2	conceived and designed the study|performed the analyses|wrote the manuscript with the	wrote the manuscript with the	Wrote the paper	Writing - Original Draft	YES
4979189	27506932	OO	2	conducted the experiments	conducted the experiments	Performed the experiments	Investigation	YES
4979189	27506932	TK	2	conducted the experiments	conducted the experiments	Performed the experiments	Investigation	YES
4979189	27506932	TS	2	performed the analyses	performed the analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4979189	27506932	all of the authors	2	helped with the wrote the manuscript with the	helped with the wrote the manuscript with the	Wrote the paper	Writing - Original Draft	YES
3048470	21314929	All authors	2	conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
3048470	21314929	GM	2	led the field research	led the field research	-	-	NO
3048470	21314929	KWT	2	led the field research	led the field research	-	-	NO
5413553	28515738	AK	CRediT	Conceptualization|investigation|writing - review and editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
5413553	28515738	AK	CRediT	Conceptualization|investigation|writing - review and editing	investigation	Performed the experiments	Investigation	YES
5413553	28515738	AK	CRediT	Conceptualization|investigation|writing - review and editing	writing - review and editing	Wrote the paper	Writing - Review & Editing	YES
5413553	28515738	DH	CRediT	investigation|writing - review and editing	investigation	Performed the experiments	Investigation	YES
5413553	28515738	DH	CRediT	investigation|writing - review and editing	writing - review and editing	Wrote the paper	Writing - Review & Editing	YES
5413553	28515738	DK	CRediT	Conceptualization|investigation|writing - review and editing|funding acquisition	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
5413553	28515738	DK	CRediT	Conceptualization|investigation|writing - review and editing|funding acquisition	investigation	Performed the experiments	Investigation	YES
5413553	28515738	DK	CRediT	Conceptualization|investigation|writing - review and editing|funding acquisition	writing - review and editing	Wrote the paper	Writing - Review & Editing	YES
5413553	28515738	DK	CRediT	Conceptualization|investigation|writing - review and editing|funding acquisition	funding acquisition	-	Funding acquisition	YES
5413553	28515738	DS	CRediT	investigation	investigation	Performed the experiments	Investigation	YES
5413553	28515738	EO	CRediT	Conceptualization|investigation	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
5413553	28515738	EO	CRediT	Conceptualization|investigation	investigation	Performed the experiments	Investigation	YES
5413553	28515738	JC	CRediT	investigation	investigation	Performed the experiments	Investigation	YES
5413553	28515738	JF	CRediT	investigation|writing - review and editing	investigation	Performed the experiments	Investigation	YES
5413553	28515738	JF	CRediT	investigation|writing - review and editing	writing - review and editing	Wrote the paper	Writing - Review & Editing	YES
5413553	28515738	KK	CRediT	Conceptualization|investigation|writing - review and editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
5413553	28515738	KK	CRediT	Conceptualization|investigation|writing - review and editing	investigation	Performed the experiments	Investigation	YES
5413553	28515738	KK	CRediT	Conceptualization|investigation|writing - review and editing	writing - review and editing	Wrote the paper	Writing - Review & Editing	YES
5413553	28515738	LS	CRediT	investigation	investigation	Performed the experiments	Investigation	YES
5413553	28515738	MS-C	CRediT	investigation	investigation	Performed the experiments	Investigation	YES
5413553	28515738	NF	CRediT	investigation|writing - review and editing	investigation	Performed the experiments	Investigation	YES
5413553	28515738	NF	CRediT	investigation|writing - review and editing	writing - review and editing	Wrote the paper	Writing - Review & Editing	YES
4979190	27506548	GL	2	assisted in transcriptome mapping and functional gene analysis|revised the manuscript and approved the final version for submission	assisted in transcriptome mapping and functional gene analysis	-	-	NO
4979190	27506548	GL	2	assisted in transcriptome mapping and functional gene analysis|revised the manuscript and approved the final version for submission	revised the manuscript and approved the final version for submission	Wrote the paper	Writing - Review & Editing	YES
4979190	27506548	LLG	2	designed the experiments|participated in the animal study and collected rumen tissue samples|revised the manuscript and approved the final version for submission	designed the experiments	Conceived and designed the experiments	Methodology	YES
4979190	27506548	LLG	2	designed the experiments|participated in the animal study and collected rumen tissue samples|revised the manuscript and approved the final version for submission	participated in the animal study and collected rumen tissue samples	Performed the experiments	Investigation	YES
4979190	27506548	LLG	2	designed the experiments|participated in the animal study and collected rumen tissue samples|revised the manuscript and approved the final version for submission	revised the manuscript and approved the final version for submission	Wrote the paper	Writing - Review & Editing	YES
4979190	27506548	PS	2	revised the manuscript and approved the final version for submission	revised the manuscript and approved the final version for submission	Wrote the paper	Writing - Review & Editing	YES
4979190	27506548	RSGK	2	designed the experiments|performed the experiments, data analysis, interpretation, and wrote the manuscript|revised the manuscript and approved the final version for submission	designed the experiments	Conceived and designed the experiments	Methodology	YES
4979190	27506548	RSGK	2	designed the experiments|performed the experiments, data analysis, interpretation, and wrote the manuscript|revised the manuscript and approved the final version for submission	performed the experiments, data analysis, interpretation, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4979190	27506548	RSGK	2	designed the experiments|performed the experiments, data analysis, interpretation, and wrote the manuscript|revised the manuscript and approved the final version for submission	revised the manuscript and approved the final version for submission	Wrote the paper	Writing - Review & Editing	YES
4979190	27506548	YC	2	designed the experiments|assisted in rna extraction and qpcr|revised the manuscript and approved the final version for submission	designed the experiments	Conceived and designed the experiments	Methodology	YES
4979190	27506548	YC	2	designed the experiments|assisted in rna extraction and qpcr|revised the manuscript and approved the final version for submission	assisted in rna extraction and qpcr	Performed the experiments	Investigation	YES
4979190	27506548	YC	2	designed the experiments|assisted in rna extraction and qpcr|revised the manuscript and approved the final version for submission	revised the manuscript and approved the final version for submission	Wrote the paper	Writing - Review & Editing	YES
3050783	21345234	All authors	2	contributed to the development of the hypothesis and analysis plan|commented on drafts and approved the final version of the manuscript	contributed to the development of the hypothesis and analysis plan	Conceived and designed the experiments	Conceptualization	YES
3050783	21345234	All authors	2	contributed to the development of the hypothesis and analysis plan|commented on drafts and approved the final version of the manuscript	commented on drafts and approved the final version of the manuscript	Wrote the paper	Writing - Original Draft	YES
3050783	21345234	HM	2	performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
3050783	21345234	MGL	2	performed the statistical analysis|wrote the first draft of the manuscript	performed the statistical analysis	Analyzed the data	Formal analysis	YES
3050783	21345234	MGL	2	performed the statistical analysis|wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
5548245	28943621	All authors	2	discussed, edited and approved the final version	discussed, edited and approved the final version	Wrote the paper	Writing - Review & Editing	YES
5548245	28943621	T.K.	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5413554	28515737	JS	7	performed the experiments with regular advice from XD and ZN	performed the experiments with regular advice from XD and ZN	Performed the experiments	Investigation	YES
5413554	28515737	QX	7	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5413554	28515737	SZ	7	performed the experiments with regular advice from XD and ZN	performed the experiments with regular advice from XD and ZN	Performed the experiments	Investigation	YES
5413554	28515737	WL	7	performed the experiments with regular advice from XD and ZN	performed the experiments with regular advice from XD and ZN	Performed the experiments	Investigation	YES
5413554	28515737	XD	7	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5413554	28515737	ZN	7	analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5413554	28515737	ZN	7	analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4981961	27516065	FG	PLoS52	performed the experiments, analyzed the data and co-wrote the manuscript	performed the experiments, analyzed the data and co-wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4981961	27516065	FN	PLoS52	analyzed the data and co-wrote	analyzed the data and co-wrote	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4981961	27516065	JF	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
4981961	27516065	JL	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
4981961	27516065	QL	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
4981961	27516065	SX	PLoS52	supervised the project and revised the manuscript	supervised the project and revised the manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
3050784	21324140	GG	2	undertook study conception and design, and critical revision of the manuscript	undertook study conception and design, and critical revision of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Writing - Review & Editing	YES
3050784	21324140	IC	2	was responsible for acquisition of data, analysis and interpretation of data, and drafting of the manuscript	was responsible for acquisition of data, analysis and interpretation of data, and drafting of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3050784	21324140	KG	2	undertook acquisition of data, and drafting of the manuscript	undertook acquisition of data, and drafting of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3050784	21324140	MW	2	was responsible for analysis and interpretation of data, and drafting of the manuscript	was responsible for analysis and interpretation of data, and drafting of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3050784	21324140	NR	2	undertook acquisition of data	undertook acquisition of data	Performed the experiments	Investigation	YES
3050784	21324140	SR	2	was responsible for analysis and interpretation of data, and drafting of the manuscript	was responsible for analysis and interpretation of data, and drafting of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5548246	28943620	Augustine S. Lee	2	contributed to the conception and design of the study, analysis and interpretation of the data, and critical revision of the article	contributed to the conception and design of the study, analysis and interpretation of the data, and critical revision of the article	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Methodology|Resources|Writing - Review & Editing	YES
5548246	28943620	Charles D. Burger	2	contributed to the conception and design of the study, collection of the data, and critical revision of the article	contributed to the conception and design of the study, collection of the data, and critical revision of the article	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Investigation|Methodology|Resources|Writing - Review & Editing	YES
5548246	28943620	Kamonpun Ussavarungsi	2	contributed to the collection, analysis, and interpretation of data, drafting and critical revision of the article, and generation of the tables	contributed to the collection, analysis, and interpretation of data, drafting and critical revision of the article, and generation of the tables	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5413559	28515736	CC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed to the writing of the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5413559	28515736	CC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed to the writing of the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
5413559	28515736	CC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed to the writing of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
5413559	28515736	CC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed to the writing of the manuscript	Contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5413559	28515736	HC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5413559	28515736	HC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
5413559	28515736	HC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5413559	28515736	HL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5413559	28515736	KW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed to the writing of the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5413559	28515736	KW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed to the writing of the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
5413559	28515736	KW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed to the writing of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
5413559	28515736	KW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed to the writing of the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5413559	28515736	KW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed to the writing of the manuscript	Contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5413559	28515736	LR	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5413559	28515736	LW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5413559	28515736	RS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5413559	28515736	XZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5413559	28515736	ZL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
3058075	21306608	All authors	2	listed below have equally contributed to the study	listed below have equally contributed to the study	-	-	NO
4395444	25875229	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4395444	25875229	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4395444	25875229	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4395444	25875229	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4395444	25875229	BJR	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4395444	25875229	BJR	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4395444	25875229	EBL	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4395444	25875229	EBL	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4395444	25875229	HLM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Coordinated public science components of project	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4395444	25875229	HLM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Coordinated public science components of project	Performed the experiments	Performed the experiments	Investigation	YES
4395444	25875229	HLM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Coordinated public science components of project	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4395444	25875229	HLM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Coordinated public science components of project	Coordinated public science components of project	-	Project administration	YES
4395444	25875229	JBH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4395444	25875229	JBH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4395444	25875229	JBH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4395444	25875229	JBH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4395444	25875229	JWL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4395444	25875229	JWL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4395444	25875229	JWL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4395444	25875229	JWL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4395444	25875229	KP	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4395444	25875229	KP	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4395444	25875229	NF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4395444	25875229	NF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4395444	25875229	NF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4395444	25875229	NF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4395444	25875229	NF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4395444	25875229	NSG	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4395444	25875229	NSG	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4395444	25875229	RRD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4395444	25875229	RRD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4395444	25875229	RRD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4395444	25875229	RRD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4395444	25875229	RRD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4981969	27515776	CB	2	carried out the construction, purification and selection of the libraries	carried out the construction, purification and selection of the libraries	Performed the experiments	Investigation	YES
4981969	27515776	DS	2	conceived the study, participated in its design and coordination, and edited the manuscript	conceived the study, participated in its design and coordination, and edited the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Review & Editing	YES
4981969	27515776	GV	2	participated in study coordination and project, and critically revised the manuscript	participated in study coordination and project, and critically revised the manuscript	Wrote the paper	Project administration|Writing - Review & Editing	YES
4981969	27515776	IS	2	performed hplc analysis	performed hplc analysis	Performed the experiments	Investigation	YES
4981969	27515776	MLG	2	participated in study coordination and project, and critically revised the manuscript	participated in study coordination and project, and critically revised the manuscript	Wrote the paper	Project administration|Writing - Review & Editing	YES
4981969	27515776	PB	2	performed the bioinformatics analysis, participated in results interpretation and critically revised the manuscript	performed the bioinformatics analysis, participated in results interpretation and critically revised the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
4981969	27515776	SM	2	performed biological assays, rna extraction, qrt pcr, analyses of bionformatic data, and wrote the manuscript	performed biological assays, rna extraction, qrt pcr, analyses of bionformatic data, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4383433	25866780	Filippo Galli	2	equally contributed to this paper	equally contributed to this paper	-	-	NO
4383433	25866780	Tiziana Lanzolla	2	equally contributed to this paper	equally contributed to this paper	-	-	NO
3059266	21385405	MAW	2	provided critical comments and edited the article	provided critical comments and edited the article	Wrote the paper	Writing - Review & Editing	YES
3059266	21385405	MJE	2	provided critical comments and edited the article	provided critical comments and edited the article	Wrote the paper	Writing - Review & Editing	YES
3059266	21385405	PPS	2	provided critical comments and edited the article	provided critical comments and edited the article	Wrote the paper	Writing - Review & Editing	YES
3059266	21385405	QAK	2	provided critical comments and edited the article	provided critical comments and edited the article	Wrote the paper	Writing - Review & Editing	YES
3059266	21385405	SH	2	wrote the first draft of the article	wrote the first draft of the article	Wrote the paper	Writing - Original Draft	YES
3059266	21385405	SK	2	provided critical comments and edited the article	provided critical comments and edited the article	Wrote the paper	Writing - Review & Editing	YES
5548248	28943616	All authors	2	contributed to the submitted work	contributed to the submitted work	-	-	NO
5548248	28943616	JT	2	wrote and supervised the review	wrote and supervised the review	Wrote the paper	Supervision|Writing - Original Draft	YES
5548248	28943616	KM	2	prepared the figures	prepared the figures	-	Visualization	YES
5548248	28943616	ME	2	wrote and supervised the review	wrote and supervised the review	Wrote the paper	Supervision|Writing - Original Draft	YES
5413563	28515734	All authors	PLoS52	analyzed and interpreted the data	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5413563	28515734	MM	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5413563	28515734	PD	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5413563	28515734	PJ	PLoS52	wrote the manuscript, planned and designed the experiments	wrote the manuscript, planned and designed the experiments	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
5413563	28515734	SP	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5413563	28515734	TS	PLoS52	wrote the manuscript, planned and designed the experiments|performed the experiments	wrote the manuscript, planned and designed the experiments	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
5413563	28515734	TS	PLoS52	wrote the manuscript, planned and designed the experiments|performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5548249	28943618	HNB	2	provided comments and finalized the manuscript	provided comments and finalized the manuscript	Wrote the paper	Writing - Review & Editing	YES
5548249	28943618	MV	2	contributed in developing the outline and preparing the first draft of the manuscript	contributed in developing the outline and preparing the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
4981973	27515907	AH	2	implemented the workflows and performed the computational analysis	implemented the workflows and performed the computational analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
4981973	27515907	All authors	2	contributed to the interpretation of the data and the writing of the manuscript	contributed to the interpretation of the data and the writing of the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
4981973	27515907	CAVH	2	implemented the workflows and performed the computational analysis	implemented the workflows and performed the computational analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
4981973	27515907	CIBS	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
4981973	27515907	LRM	2	implemented the workflows and performed the computational analysis	implemented the workflows and performed the computational analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
4981973	27515907	MHR	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
4981973	27515907	NR	2	implemented the workflows and performed the computational analysis	implemented the workflows and performed the computational analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
4981973	27515907	PFS	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
4981973	27515907	SJB	2	implemented the workflows and performed the computational analysis	implemented the workflows and performed the computational analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
3064618	21406080	HE	2	conceived the main arguments of the paper and wrote the first draft	conceived the main arguments of the paper and wrote the first draft	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
3064618	21406080	MM	2	made extensive revisions and other intellectual contributions	made extensive revisions and other intellectual contributions	Wrote the paper	Writing - Review & Editing	YES
4395447	25875932	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4395447	25875932	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4395447	25875932	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4395447	25875932	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4395447	25875932	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4395447	25875932	DM	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4395447	25875932	SC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4395447	25875932	SC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4395447	25875932	SC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4395447	25875932	SC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4395447	25875932	SC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4395447	25875932	SN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4395447	25875932	SN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4395447	25875932	SN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4395447	25875932	SN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4395447	25875932	SN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3065394	21406079	SMG	2	is responsible for all aspects of the manuscript and has read and approved the final version of this manuscript	is responsible for all aspects of the manuscript and has read and approved the final version of this manuscript	-	-	NO
4981982	27515123	All authors	2	contributed to manuscript writing	contributed to manuscript writing	Wrote the paper	Writing - Original Draft	YES
4981982	27515123	GL	2	performed experiments and data analysis and draft writing	performed experiments and data analysis and draft writing	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4981982	27515123	HB	2	contributed to sequencing data analysis pipeline	contributed to sequencing data analysis pipeline	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
4981982	27515123	LLG	2	designed experiment, contributed to data analysis and interpretation and finalized the manuscript	designed experiment, contributed to data analysis and interpretation and finalized the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
4981982	27515123	NM	2	contributed to animal study, qpcr experiment and data analysis	contributed to animal study, qpcr experiment and data analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
4981982	27515123	PJG	2	contributed in data interpretation and manuscript preparation	contributed in data interpretation and manuscript preparation	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
4981982	27515123	PS	2	contributed to sequencing data analysis pipeline	contributed to sequencing data analysis pipeline	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5413564	28515730	DH	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5413564	28515730	JG	2	designed and supervised experiments	designed and supervised experiments	Conceived and designed the experiments	Methodology|Supervision	YES
5413564	28515730	JL	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5413564	28515730	LL	2	performed all the experiments, data analysis and wrote the paper	performed all the experiments, data analysis and wrote the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5413564	28515730	QB	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5413564	28515730	SM	2	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5413564	28515730	WG	2	performed all the experiments, data analysis and wrote the paper	performed all the experiments, data analysis and wrote the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5413564	28515730	XL	2	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5413564	28515730	YM	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5413564	28515730	ZC	2	performed all the experiments, data analysis and wrote the paper	performed all the experiments, data analysis and wrote the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5548255	28943628	AM	2	contributed to the design, writing and editing of the review	contributed to the design, writing and editing of the review	Conceived and designed the experiments|Wrote the paper	Writing - Review & Editing	YES
5548255	28943628	AMC	2	contributed to the writing and editing of the review	contributed to the writing and editing of the review	Wrote the paper	Writing - Review & Editing	YES
5548255	28943628	FB	2	contributed to the writing and editing of the review	contributed to the writing and editing of the review	Wrote the paper	Writing - Review & Editing	YES
5548255	28943628	MT	2	contributed to the design, writing and editing of the review	contributed to the design, writing and editing of the review	Conceived and designed the experiments|Wrote the paper	Writing - Review & Editing	YES
4395448	25875652	EG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4395448	25875652	EG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4395448	25875652	EG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3072300	21439074	AD	2	were in charge of the esther patients medical follow up	were in charge of the esther patients medical follow up	-	-	NO
3072300	21439074	CH	2	were in charge of the esther patients medical follow up	were in charge of the esther patients medical follow up	-	-	NO
3072300	21439074	CM	2	conceived and designed the study protocol	conceived and designed the study protocol	Conceived and designed the experiments	Conceptualization|Methodology	YES
3072300	21439074	EN	2	conceived and designed the study protocol|led the writing of the manuscript	conceived and designed the study protocol	Conceived and designed the experiments	Conceptualization|Methodology	YES
3072300	21439074	EN	2	conceived and designed the study protocol|led the writing of the manuscript	led the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
3072300	21439074	IF	2	contributed to the data collection in the field	contributed to the data collection in the field	Performed the experiments	Investigation	YES
3072300	21439074	JFD	2	conceived and designed the study protocol	conceived and designed the study protocol	Conceived and designed the experiments	Conceptualization|Methodology	YES
3072300	21439074	LF	2	conceived and designed the study protocol|did the statistical analysis|led the writing of the manuscript	conceived and designed the study protocol	Conceived and designed the experiments	Conceptualization|Methodology	YES
3072300	21439074	LF	2	conceived and designed the study protocol|did the statistical analysis|led the writing of the manuscript	did the statistical analysis	Analyzed the data	Formal analysis	YES
3072300	21439074	LF	2	conceived and designed the study protocol|did the statistical analysis|led the writing of the manuscript	led the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
3072300	21439074	NL	2	contributed to the data collection in the field	contributed to the data collection in the field	Performed the experiments	Investigation	YES
3072300	21439074	OS	2	were in charge of the esther patients medical follow up	were in charge of the esther patients medical follow up	-	-	NO
3072300	21439074	VO	2	were in charge of the esther patients medical follow up	were in charge of the esther patients medical follow up	-	-	NO
5413569	28515735	BL	2	provided technical assistance to tz and cg	provided technical assistance to tz and cg	Performed the experiments	Investigation	YES
5413569	28515735	BY	2	supervised the experiments	supervised the experiments	-	Supervision	YES
5413569	28515735	CG	2	designed and performed the research, analyzed data, and wrote the article with contributions of all the authors	designed and performed the research, analyzed data, and wrote the article with contributions of all the authors	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5413569	28515735	CM	2	supervised the experiments|supervised and complemented the writing	supervised the experiments	-	Supervision	YES
5413569	28515735	CM	2	supervised the experiments|supervised and complemented the writing	supervised and complemented the writing	Wrote the paper	Supervision	YES
5413569	28515735	GZ	2	provided technical assistance to tz and cg	provided technical assistance to tz and cg	Performed the experiments	Investigation	YES
5413569	28515735	JS	2	supervised the experiments	supervised the experiments	-	Supervision	YES
5413569	28515735	JT	2	supervised the experiments	supervised the experiments	-	Supervision	YES
5413569	28515735	JW	2	supervised the experiments	supervised the experiments	-	Supervision	YES
5413569	28515735	TF	2	supervised the experiments	supervised the experiments	-	Supervision	YES
5413569	28515735	TZ	2	designed and performed the research, analyzed data, and wrote the article with contributions of all the authors	designed and performed the research, analyzed data, and wrote the article with contributions of all the authors	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5413569	28515735	YAY	2	performed research and analyzed data	performed research and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5413569	28515735	YOY	2	provided technical assistance to tz and cg	provided technical assistance to tz and cg	Performed the experiments	Investigation	YES
5413569	28515735	ZD	2	provided technical assistance to tz and cg	provided technical assistance to tz and cg	Performed the experiments	Investigation	YES
5413569	28515735	ZL	2	performed research and analyzed data	performed research and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5548256	28943625	C.C.	PLoS52	wrote the paper|contributed to the revision of the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5548256	28943625	C.C.	PLoS52	wrote the paper|contributed to the revision of the paper	contributed to the revision of the paper	Wrote the paper	Writing - Review & Editing	YES
5548256	28943625	E.L.	PLoS52	performed the review of literature and analyzed the data|wrote the paper|contributed to the revision of the paper	performed the review of literature and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5548256	28943625	E.L.	PLoS52	performed the review of literature and analyzed the data|wrote the paper|contributed to the revision of the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5548256	28943625	E.L.	PLoS52	performed the review of literature and analyzed the data|wrote the paper|contributed to the revision of the paper	contributed to the revision of the paper	Wrote the paper	Writing - Review & Editing	YES
4981986	27519651	FM	2	drafted the manuscript with	drafted the manuscript with	Wrote the paper	Writing - Original Draft	YES
4981986	27519651	HQ	2	performed genome annotation|contributed with the drafted the manuscript with|advised on the statistical analysis	performed genome annotation	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
4981986	27519651	HQ	2	performed genome annotation|contributed with the drafted the manuscript with|advised on the statistical analysis	contributed with the drafted the manuscript with	Wrote the paper	Writing - Original Draft	YES
4981986	27519651	HQ	2	performed genome annotation|contributed with the drafted the manuscript with|advised on the statistical analysis	advised on the statistical analysis	Analyzed the data	Formal analysis	YES
4981986	27519651	LM	2	contributed with the drafted the manuscript with|made the sl2	contributed with the drafted the manuscript with	Wrote the paper	Writing - Original Draft	YES
4981986	27519651	LM	2	contributed with the drafted the manuscript with|made the sl2	made the sl2	-	-	NO
4981986	27519651	OJ	2	performed genome annotation|performed all the analyses and prepared the manuscript for publication|drafted the manuscript with	performed genome annotation	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
4981986	27519651	OJ	2	performed genome annotation|performed all the analyses and prepared the manuscript for publication|drafted the manuscript with	performed all the analyses and prepared the manuscript for publication	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4981986	27519651	OJ	2	performed genome annotation|performed all the analyses and prepared the manuscript for publication|drafted the manuscript with	drafted the manuscript with	Wrote the paper	Writing - Original Draft	YES
4981986	27519651	SS	2	contributed with the drafted the manuscript with|performed the conversion of genome annotation from sl2|made the sl2	contributed with the drafted the manuscript with	Wrote the paper	Writing - Original Draft	YES
4981986	27519651	SS	2	contributed with the drafted the manuscript with|performed the conversion of genome annotation from sl2|made the sl2	performed the conversion of genome annotation from sl2	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
4981986	27519651	SS	2	contributed with the drafted the manuscript with|performed the conversion of genome annotation from sl2|made the sl2	made the sl2	-	-	NO
4981986	27519651	all authors	2	have read and approved the final version of the manuscript	have read and approved the final version of the manuscript	-	-	NO
3072916	21443771	MD	2	extracted the data, and performed part of the statistical analysis	extracted the data, and performed part of the statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3072916	21443771	NC	2	participated in study design, and reviewed the draft	participated in study design, and reviewed the draft	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3072916	21443771	ND	2	participated in the study design, reviewed the clinical charts, performed data analysis and statistical analysis, and writing of the paper	participated in the study design, reviewed the clinical charts, performed data analysis and statistical analysis, and writing of the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
3072916	21443771	SDW	2	participated in the study design, data analysis, and writing of the paper	participated in the study design, data analysis, and writing of the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3072916	21443771	VCN	2	encoded the data, and was in charge of the cohort	encoded the data, and was in charge of the cohort	Analyzed the data	Data curation	YES
5548257	28943623	All authors	2	discussed, edited and approved the final version	discussed, edited and approved the final version	Wrote the paper	Writing - Review & Editing	YES
5548257	28943623	Maryam Haddadzadeh Shoushtari	2	performed the experimental work|wrote the manuscript	performed the experimental work	Performed the experiments	Investigation	YES
5548257	28943623	Maryam Haddadzadeh Shoushtari	2	performed the experimental work|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5548257	28943623	Seied Ali Javad	2	performed the experimental work	performed the experimental work	Performed the experiments	Investigation	YES
3078828	21439089	AC	2	was involved in drafting the manuscript and revising it critically for important intellectual content	was involved in drafting the manuscript and revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3078828	21439089	EtH	2	was involved in the conception and design of the study, analysis and interpretation of data, drafting the manuscript, and revising it critically for important intellectual content	was involved in the conception and design of the study, analysis and interpretation of data, drafting the manuscript, and revising it critically for important intellectual content	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
3078828	21439089	JB	2	was involved in drafting the manuscript and revising it critically for important intellectual content	was involved in drafting the manuscript and revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3078828	21439089	SM	2	was involved in the conception and design of the study, analysis and interpretation of data, drafting the manuscript, and revising it critically for important intellectual content	was involved in the conception and design of the study, analysis and interpretation of data, drafting the manuscript, and revising it critically for important intellectual content	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
4981992	27514659	AMC	2	assisted in microarray experiments, participated in drafting the manuscript and oversaw data analysis	assisted in microarray experiments, participated in drafting the manuscript and oversaw data analysis	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Supervision|Writing - Original Draft	YES
4981992	27514659	All authors	2	critically read, revised and approved the manuscript	critically read, revised and approved the manuscript	Wrote the paper	Writing - Review & Editing	YES
4981992	27514659	CAG	2	conceived and directed the study	conceived and directed the study	Conceived and designed the experiments	Conceptualization|Supervision	YES
4981992	27514659	CJM	2	contributed to the design of the experiments and data analysis	contributed to the design of the experiments and data analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Methodology|Resources	YES
4981992	27514659	DW	2	conceived and directed the study	conceived and directed the study	Conceived and designed the experiments	Conceptualization|Supervision	YES
4981992	27514659	HL	2	designed the experiments, performed the experiments, analyzed all data and wrote the manuscript	designed the experiments, performed the experiments, analyzed all data and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4981992	27514659	JAJ	2	conceived and directed the study	conceived and directed the study	Conceived and designed the experiments	Conceptualization|Supervision	YES
5414387	28515731	AC	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5414387	28515731	All the authors	PLoS52	contributed to the writing, discussion and approval of the final manuscript	contributed to the writing, discussion and approval of the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5414387	28515731	BR	PLoS52	performed the experiments|are to be considered equal joint first authors	performed the experiments	Performed the experiments	Investigation	YES
5414387	28515731	BR	PLoS52	performed the experiments|are to be considered equal joint first authors	are to be considered equal joint first authors	-	-	NO
5414387	28515731	JC	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5414387	28515731	JC	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5414387	28515731	JD	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5414387	28515731	JF	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5414387	28515731	JM	PLoS52	conceived and designed the experiments|analyzed the data	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5414387	28515731	JM	PLoS52	conceived and designed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5414387	28515731	JV	PLoS52	conceived and designed the experiments|analyzed the data	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5414387	28515731	JV	PLoS52	conceived and designed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5414387	28515731	LC	PLoS52	performed the experiments|are to be considered equal joint first authors	performed the experiments	Performed the experiments	Investigation	YES
5414387	28515731	LC	PLoS52	performed the experiments|are to be considered equal joint first authors	are to be considered equal joint first authors	-	-	NO
5414387	28515731	MS	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5414387	28515731	RM	PLoS52	conceived and designed the experiments|analyzed the data|are to be considered equal joint first authors	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5414387	28515731	RM	PLoS52	conceived and designed the experiments|analyzed the data|are to be considered equal joint first authors	analyzed the data	Analyzed the data	Formal analysis	YES
5414387	28515731	RM	PLoS52	conceived and designed the experiments|analyzed the data|are to be considered equal joint first authors	are to be considered equal joint first authors	-	-	NO
5414387	28515731	SN	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5414387	28515731	SN	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5414387	28515731	SN	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5414387	28515731	SP	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
4395452	25874456	AE	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4395452	25874456	AE	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4395452	25874456	AE	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4395452	25874456	AE	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4395452	25874456	BJB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4395452	25874456	BJB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4395452	25874456	BJB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4395452	25874456	BJB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4395452	25874456	BJB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4395452	25874456	EL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4395452	25874456	EL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4395452	25874456	EL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4395452	25874456	EL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4395452	25874456	EL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4395452	25874456	FCL	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4395452	25874456	FCL	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4395452	25874456	JLF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4395452	25874456	JLF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4395452	25874456	JLF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4395452	25874456	JLF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4395452	25874456	JLF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4395452	25874456	SGE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4395452	25874456	SGE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4395452	25874456	SGE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4395452	25874456	SGE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4395452	25874456	SGE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3086828	21477317	AMC	PLoS52	contributed reagents|wrote the paper	contributed reagents	Contributed reagents/materials/analysis tools	Resources	YES
3086828	21477317	AMC	PLoS52	contributed reagents|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3086828	21477317	AT	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
3086828	21477317	CK	PLoS52	contributed to participant recruitment and follow-up testing, field site management, protocol development, and manuscript preparation	contributed to participant recruitment and follow-up testing, field site management, protocol development, and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
3086828	21477317	DIB	PLoS52	conceived and designed the experiment|performed the experiments|analyzed the data|wrote the paper	conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
3086828	21477317	DIB	PLoS52	conceived and designed the experiment|performed the experiments|analyzed the data|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
3086828	21477317	DIB	PLoS52	conceived and designed the experiment|performed the experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
3086828	21477317	DIB	PLoS52	conceived and designed the experiment|performed the experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3086828	21477317	EC	PLoS52	contributed to participant recruitment and follow-up testing, field site management, protocol development, and manuscript preparation	contributed to participant recruitment and follow-up testing, field site management, protocol development, and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
3086828	21477317	EH	PLoS52	conceived and designed the experiment|wrote the paper	conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
3086828	21477317	EH	PLoS52	conceived and designed the experiment|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3086828	21477317	EK	PLoS52	contributed to participant recruitment and follow-up testing, field site management, protocol development, and manuscript preparation	contributed to participant recruitment and follow-up testing, field site management, protocol development, and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
3086828	21477317	JB	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
3086828	21477317	KW	PLoS52	contributed to participant recruitment and follow-up testing, field site management, protocol development, and manuscript preparation	contributed to participant recruitment and follow-up testing, field site management, protocol development, and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
3086828	21477317	MK	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
3086828	21477317	NL	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
3086828	21477317	SA	PLoS52	conceived and designed the experiment|analyzed the data|wrote the paper	conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
3086828	21477317	SA	PLoS52	conceived and designed the experiment|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
3086828	21477317	SA	PLoS52	conceived and designed the experiment|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3086828	21477317	SM	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
3086828	21477317	TS	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
3086828	21477317	WK	PLoS52	contributed to participant recruitment and follow-up testing, field site management, protocol development, and manuscript preparation	contributed to participant recruitment and follow-up testing, field site management, protocol development, and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5548258	28943624	A.K.Y.	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5548258	28943624	I.M.Y.	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5548258	28943624	K.-Y.	2	edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5548258	28943624	X.H.	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4981995	27514986	AHE	PLoS52	designed the experiments|supervised the rna seq experiment and bioinformatic analysis|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
4981995	27514986	AHE	PLoS52	designed the experiments|supervised the rna seq experiment and bioinformatic analysis|wrote the manuscript	supervised the rna seq experiment and bioinformatic analysis	Performed the experiments	Formal analysis|Investigation|Supervision	YES
4981995	27514986	AHE	PLoS52	designed the experiments|supervised the rna seq experiment and bioinformatic analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4981995	27514986	All authors	PLoS52	contributed in data analysis, read and approved the final version of the manuscript	contributed in data analysis, read and approved the final version of the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
4981995	27514986	CGS	PLoS52	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
4981995	27514986	JFLH	PLoS52	performed the bioinformatic analysis	performed the bioinformatic analysis	Performed the experiments	Formal analysis|Investigation	YES
4981995	27514986	JMVE	PLoS52	performed the bioinformatic analysis|wrote the manuscript	performed the bioinformatic analysis	Performed the experiments	Formal analysis|Investigation	YES
4981995	27514986	JMVE	PLoS52	performed the bioinformatic analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4981995	27514986	MPA	PLoS52	designed the experiments|performed the experiments|performed the bioinformatic analysis|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
4981995	27514986	MPA	PLoS52	designed the experiments|performed the experiments|performed the bioinformatic analysis|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
4981995	27514986	MPA	PLoS52	designed the experiments|performed the experiments|performed the bioinformatic analysis|wrote the manuscript	performed the bioinformatic analysis	Performed the experiments	Formal analysis|Investigation	YES
4981995	27514986	MPA	PLoS52	designed the experiments|performed the experiments|performed the bioinformatic analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4981995	27514986	PR	PLoS52	designed the experiments|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
4981995	27514986	PR	PLoS52	designed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4981995	27514986	RHM	PLoS52	designed the experiments|coordinated the experiments|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
4981995	27514986	RHM	PLoS52	designed the experiments|coordinated the experiments|wrote the manuscript	coordinated the experiments	-	Project administration	YES
4981995	27514986	RHM	PLoS52	designed the experiments|coordinated the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5414482	28515729	SK-B	2	was in charge of writing up but all authors contributed to the preparation of the manuscript	was in charge of writing up but all authors contributed to the preparation of the manuscript	Wrote the paper	Writing - Original Draft	YES
3090994	21496354	AL	2	was responsible for data collection	was responsible for data collection	Performed the experiments	Investigation	YES
3090994	21496354	AME	2	were part of the study design	were part of the study design	Conceived and designed the experiments	Methodology	YES
3090994	21496354	AR	2	were part of the study design|were responsible for data analysis|drafted the first version of the manuscript	were part of the study design	Conceived and designed the experiments	Methodology	YES
3090994	21496354	AR	2	were part of the study design|were responsible for data analysis|drafted the first version of the manuscript	were responsible for data analysis	Analyzed the data	Formal analysis	YES
3090994	21496354	AR	2	were part of the study design|were responsible for data analysis|drafted the first version of the manuscript	drafted the first version of the manuscript	Wrote the paper	Writing - Original Draft	YES
3090994	21496354	AT	2	were part of the study design|were responsible for data analysis	were part of the study design	Conceived and designed the experiments	Methodology	YES
3090994	21496354	AT	2	were part of the study design|were responsible for data analysis	were responsible for data analysis	Analyzed the data	Formal analysis	YES
3090994	21496354	FI	2	were part of the study design	were part of the study design	Conceived and designed the experiments	Methodology	YES
3090994	21496354	GM	2	were responsible for data analysis	were responsible for data analysis	Analyzed the data	Formal analysis	YES
3090994	21496354	JC	2	were part of the study design	were part of the study design	Conceived and designed the experiments	Methodology	YES
6320894	30567356	E.X.	2	participated in research administration and revising the manuscript	participated in research administration and revising the manuscript	Wrote the paper	Writing - Review & Editing	YES
6320894	30567356	J.S.	2	as corresponding author, acquired the funding, participated in the study conceptualization, data analysis, reviewing and editing the manuscript, and finalized this manuscript	as corresponding author, acquired the funding, participated in the study conceptualization, data analysis, reviewing and editing the manuscript, and finalized this manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Funding acquisition|Investigation|Writing - Review & Editing	YES
6320894	30567356	M.Q.	2	participated in the conceptualization, data analysis and reviewing and editing the manuscript and acquired the funding	participated in the conceptualization, data analysis and reviewing and editing the manuscript and acquired the funding	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Funding acquisition|Writing - Review & Editing	YES
6320894	30567356	P.G.	2	participated in research administration and revising the manuscript	participated in research administration and revising the manuscript	Wrote the paper	Writing - Review & Editing	YES
6320894	30567356	X.Z.	2	participated in the experimental study, including the investigation, methodology, data curation, formal analysis of data, research administration, and drafting the original manuscript	participated in the experimental study, including the investigation, methodology, data curation, formal analysis of data, research administration, and drafting the original manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
6320894	30567356	Y.L.	2	participated in research administration and revising the manuscript	participated in research administration and revising the manuscript	Wrote the paper	Writing - Review & Editing	YES
4395454	25874865	DQH	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4395454	25874865	LYL	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4395454	25874865	NHL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4395454	25874865	SSJ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4395454	25874865	ZJL	PLoS5	Wrote the paper|Experimental design, interpret data, and write manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4395454	25874865	ZJL	PLoS5	Wrote the paper|Experimental design, interpret data, and write manuscript	Experimental design, interpret data, and write manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5415600	28523004	JH	PLoS52	contributed reagents/materials	contributed reagents/materials	Contributed reagents/materials/analysis tools	Resources	YES
5415600	28523004	JN	PLoS52	performed the experiments|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5415600	28523004	JN	PLoS52	performed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5415600	28523004	LW	PLoS52	edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5415600	28523004	ML	PLoS52	contributed reagents/materials	contributed reagents/materials	Contributed reagents/materials/analysis tools	Resources	YES
5415600	28523004	QW	PLoS52	contributed reagents/materials	contributed reagents/materials	Contributed reagents/materials/analysis tools	Resources	YES
5415600	28523004	SH	PLoS52	contributed reagents/materials	contributed reagents/materials	Contributed reagents/materials/analysis tools	Resources	YES
5415600	28523004	WL	PLoS52	contributed reagents/materials	contributed reagents/materials	Contributed reagents/materials/analysis tools	Resources	YES
5415600	28523004	WZ	PLoS52	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5415600	28523004	XC	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5415600	28523004	XC	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5415600	28523004	XC	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5415600	28523004	XC	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5415600	28523004	YM	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5415600	28523004	YM	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5415600	28523004	YM	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5415600	28523004	YW	PLoS52	contributed reagents/materials	contributed reagents/materials	Contributed reagents/materials/analysis tools	Resources	YES
5548259	28943630	H.T.	2	prepared subsequent drafts, and approved the final manuscript draft prior to submission	prepared subsequent drafts, and approved the final manuscript draft prior to submission	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5548259	28943630	I.O.	2	prepared subsequent drafts, and approved the final manuscript draft prior to submission	prepared subsequent drafts, and approved the final manuscript draft prior to submission	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5548259	28943630	K.U.	2	prepared subsequent drafts, and approved the final manuscript draft prior to submission	prepared subsequent drafts, and approved the final manuscript draft prior to submission	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5548259	28943630	K.W.	2	prepared subsequent drafts, and approved the final manuscript draft prior to submission	prepared subsequent drafts, and approved the final manuscript draft prior to submission	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5548259	28943630	M.I.	2	prepared the initial draft of the manuscript|prepared subsequent drafts, and approved the final manuscript draft prior to submission	prepared the initial draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
5548259	28943630	M.I.	2	prepared the initial draft of the manuscript|prepared subsequent drafts, and approved the final manuscript draft prior to submission	prepared subsequent drafts, and approved the final manuscript draft prior to submission	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5548259	28943630	S.M.	2	prepared subsequent drafts, and approved the final manuscript draft prior to submission	prepared subsequent drafts, and approved the final manuscript draft prior to submission	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5548259	28943630	T.O.	2	prepared subsequent drafts, and approved the final manuscript draft prior to submission	prepared subsequent drafts, and approved the final manuscript draft prior to submission	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5548259	28943630	Y.H.	2	prepared subsequent drafts, and approved the final manuscript draft prior to submission	prepared subsequent drafts, and approved the final manuscript draft prior to submission	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4981999	27515254	CB	2	extracted the dna	extracted the dna	Performed the experiments	Investigation	YES
4981999	27515254	CP	2	were involved in the writing and editing of the manuscript	were involved in the writing and editing of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4981999	27515254	FI	2	were involved in the writing and editing of the manuscript	were involved in the writing and editing of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4981999	27515254	JB	2	performed the analysis and wrote the first draft of the manuscript	performed the analysis and wrote the first draft of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4981999	27515254	JVH	2	selected the reference population|were involved in the writing and editing of the manuscript	selected the reference population	-	-	NO
4981999	27515254	JVH	2	selected the reference population|were involved in the writing and editing of the manuscript	were involved in the writing and editing of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4981999	27515254	LB	2	selected the reference population|were involved in the writing and editing of the manuscript|designed and coordinated the study	selected the reference population	-	-	NO
4981999	27515254	LB	2	selected the reference population|were involved in the writing and editing of the manuscript|designed and coordinated the study	were involved in the writing and editing of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4981999	27515254	LB	2	selected the reference population|were involved in the writing and editing of the manuscript|designed and coordinated the study	designed and coordinated the study	Conceived and designed the experiments	Methodology|Project administration	YES
4981999	27515254	MV	2	selected the reference population	selected the reference population	-	-	NO
6320896	30400294	C.D.M.	CRediT	funding acquisition	funding acquisition	-	Funding acquisition	YES
6320896	30400294	M.B.	CRediT	funding acquisition	funding acquisition	-	Funding acquisition	YES
6320896	30400294	M.G.-A.	CRediT	writing--review and editing|supervision	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6320896	30400294	M.G.-A.	CRediT	writing--review and editing|supervision	supervision	-	Supervision	YES
6320896	30400294	P.M.	CRediT	writing--review and editing|supervision|funding acquisition	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6320896	30400294	P.M.	CRediT	writing--review and editing|supervision|funding acquisition	supervision	-	Supervision	YES
6320896	30400294	P.M.	CRediT	writing--review and editing|supervision|funding acquisition	funding acquisition	-	Funding acquisition	YES
6320896	30400294	all other authors	CRediT	writing--original draft preparation	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
3094357	21477359	AM	2	drafted the manuscript, which all authors reviewed, edited and approved	drafted the manuscript, which all authors reviewed, edited and approved	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3094357	21477359	BS	2	performed the statistical analyses	performed the statistical analyses	Analyzed the data	Formal analysis	YES
3094357	21477359	CN	2	were responsible for study design and data collection	were responsible for study design and data collection	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3094357	21477359	CW	2	drafted the manuscript, which all authors reviewed, edited and approved	drafted the manuscript, which all authors reviewed, edited and approved	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3094357	21477359	DH	2	were responsible for study design and data collection	were responsible for study design and data collection	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3094357	21477359	EK	2	were responsible for study design and data collection|performed the laboratory analyses|drafted the manuscript, which all authors reviewed, edited and approved	were responsible for study design and data collection	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3094357	21477359	EK	2	were responsible for study design and data collection|performed the laboratory analyses|drafted the manuscript, which all authors reviewed, edited and approved	performed the laboratory analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3094357	21477359	EK	2	were responsible for study design and data collection|performed the laboratory analyses|drafted the manuscript, which all authors reviewed, edited and approved	drafted the manuscript, which all authors reviewed, edited and approved	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3094357	21477359	IZ	2	were responsible for study design and data collection	were responsible for study design and data collection	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3094357	21477359	JC	2	performed the laboratory analyses|drafted the manuscript, which all authors reviewed, edited and approved	performed the laboratory analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3094357	21477359	JC	2	performed the laboratory analyses|drafted the manuscript, which all authors reviewed, edited and approved	drafted the manuscript, which all authors reviewed, edited and approved	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3094357	21477359	JK	2	performed the statistical analyses|drafted the manuscript, which all authors reviewed, edited and approved	performed the statistical analyses	Analyzed the data	Formal analysis	YES
3094357	21477359	JK	2	performed the statistical analyses|drafted the manuscript, which all authors reviewed, edited and approved	drafted the manuscript, which all authors reviewed, edited and approved	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3094357	21477359	LM	2	were responsible for study design and data collection	were responsible for study design and data collection	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3094357	21477359	MB	2	performed the statistical analyses|drafted the manuscript, which all authors reviewed, edited and approved	performed the statistical analyses	Analyzed the data	Formal analysis	YES
3094357	21477359	MB	2	performed the statistical analyses|drafted the manuscript, which all authors reviewed, edited and approved	drafted the manuscript, which all authors reviewed, edited and approved	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4395456	25874615	CL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4395456	25874615	HW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4395456	25874615	HY	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4395456	25874615	HY	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4395456	25874615	HY	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4395456	25874615	HY	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4395456	25874615	JZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4395456	25874615	LL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4395456	25874615	LL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4395456	25874615	LL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4395456	25874615	LL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4395456	25874615	LQ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4395456	25874615	LW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4395456	25874615	MG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4395456	25874615	MG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4395456	25874615	MG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4395456	25874615	TL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4395456	25874615	TL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4395456	25874615	TX	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4395456	25874615	TX	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4395456	25874615	TZ	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4395456	25874615	TZ	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4395456	25874615	WS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4395456	25874615	XG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4395456	25874615	XW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4395456	25874615	YW	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4395456	25874615	YW	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4395456	25874615	YW	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4395456	25874615	YZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
3108267	21521511	All authors	2	participated in the design and planning of the study	participated in the design and planning of the study	Conceived and designed the experiments	Methodology	YES
5548260	28943627	J.J.C.	2	performed research and wrote the paper	performed research and wrote the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5548260	28943627	J.J.X.L.	2	performed research and wrote the paper	performed research and wrote the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5548260	28943627	S.P.C.	2	conceptualized and designed the article	conceptualized and designed the article	Conceived and designed the experiments	Conceptualization	YES
6320905	30248922	A.P.	1	Conceived and designed the manuscript	Conceived and designed the manuscript	Conceived and designed the experiments	Conceptualization	YES
6320905	30248922	M.J.H.	1	Conceived and designed the manuscript	Conceived and designed the manuscript	Conceived and designed the experiments	Conceptualization	YES
6320905	30248922	M.Z.	1	Conceived and designed the manuscript	Conceived and designed the manuscript	Conceived and designed the experiments	Conceptualization	YES
6320905	30248922	P.A.D.	1	Conceived and designed the manuscript	Conceived and designed the manuscript	Conceived and designed the experiments	Conceptualization	YES
5415602	28523014	All authors	2	listed, have made substantial, direct and intellectual contribution to the work, and approved it for publication	listed, have made substantial, direct and intellectual contribution to the work, and approved it for publication	-	-	NO
4982002	27515927	HD	2	performed rna seq and analysis of the resulting data|gave advice on the experiments, data analysis	performed rna seq and analysis of the resulting data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4982002	27515927	HD	2	performed rna seq and analysis of the resulting data|gave advice on the experiments, data analysis	gave advice on the experiments, data analysis	Analyzed the data	Formal analysis	YES
4982002	27515927	HH	2	conceived the project and designed outlines most of the experiments|wrote the manuscript	conceived the project and designed outlines most of the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4982002	27515927	HH	2	conceived the project and designed outlines most of the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4982002	27515927	HKaw	2	gave advice on the experiments, data analysis	gave advice on the experiments, data analysis	Analyzed the data	Formal analysis	YES
4982002	27515927	IK	2	provided phlebia sp	provided phlebia sp	-	-	NO
4982002	27515927	JW	2	performed rna seq and analysis of the resulting data|wrote the manuscript	performed rna seq and analysis of the resulting data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4982002	27515927	JW	2	performed rna seq and analysis of the resulting data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4982002	27515927	ST	2	performed rna seq and analysis of the resulting data	performed rna seq and analysis of the resulting data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4982002	27515927	TM	2	gave advice on the experiments, data analysis	gave advice on the experiments, data analysis	Analyzed the data	Formal analysis	YES
4982002	27515927	TS	2	performed rna seq and analysis of the resulting data|wrote the manuscript	performed rna seq and analysis of the resulting data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4982002	27515927	TS	2	performed rna seq and analysis of the resulting data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3349166	22593713	I. Takasaki	PLoS52	contributed genechip analytic tool and analyzed the data	contributed genechip analytic tool and analyzed the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
3349166	22593713	K. Nomoto	PLoS52	contributed equally to this work|designed the research and performed the majority of experiments|wrote the paper	contributed equally to this work	-	-	NO
3349166	22593713	K. Nomoto	PLoS52	contributed equally to this work|designed the research and performed the majority of experiments|wrote the paper	designed the research and performed the majority of experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3349166	22593713	K. Nomoto	PLoS52	contributed equally to this work|designed the research and performed the majority of experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3349166	22593713	K. Tsuneyama	PLoS52	designed the research and performed the majority of experiments|wrote the paper	designed the research and performed the majority of experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3349166	22593713	K. Tsuneyama	PLoS52	designed the research and performed the majority of experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3349166	22593713	M. Fujimoto	PLoS52	designed the research and performed the majority of experiments	designed the research and performed the majority of experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3349166	22593713	T. Nishida	PLoS52	contributed equally to this work|wrote the paper	contributed equally to this work	-	-	NO
3349166	22593713	T. Nishida	PLoS52	contributed equally to this work|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3349166	22593713	Y. Nakanishi	PLoS52	designed the research and performed the majority of experiments	designed the research and performed the majority of experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3349166	22593713	Y. Tabuchi	PLoS52	contributed genechip analytic tool and analyzed the data	contributed genechip analytic tool and analyzed the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6320908	30513861	A.C.M.	PLoS52	contributed to the development of concept, data analysis, and revision of the manuscript	contributed to the development of concept, data analysis, and revision of the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Resources|Writing - Original Draft|Writing - Review & Editing	YES
6320908	30513861	E.N.A.	PLoS52	performed the experiments|performed the literature search and drafted the manuscript	performed the experiments	Performed the experiments	Investigation	YES
6320908	30513861	E.N.A.	PLoS52	performed the experiments|performed the literature search and drafted the manuscript	performed the literature search and drafted the manuscript	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6320908	30513861	E.S.T.E.	PLoS52	contributed to the development of concept, data analysis, and revision of the manuscript	contributed to the development of concept, data analysis, and revision of the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Resources|Writing - Original Draft|Writing - Review & Editing	YES
6320908	30513861	G.M.C.	PLoS52	contributed to the development of concept, data analysis, and revision of the manuscript	contributed to the development of concept, data analysis, and revision of the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Resources|Writing - Original Draft|Writing - Review & Editing	YES
6320908	30513861	K.C.Z.	PLoS52	was responsible for the mucoadhesive assay	was responsible for the mucoadhesive assay	Performed the experiments	Investigation	YES
6320908	30513861	L.A.-M.	PLoS52	performed the experiments|performed the literature search and drafted the manuscript	performed the experiments	Performed the experiments	Investigation	YES
6320908	30513861	L.A.-M.	PLoS52	performed the experiments|performed the literature search and drafted the manuscript	performed the literature search and drafted the manuscript	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6320908	30513861	L.B.F.C.d.S.	PLoS52	were responsible for the antifungal activity assay	were responsible for the antifungal activity assay	Performed the experiments	Investigation	YES
6320908	30513861	S.S.M.-O.	PLoS52	performed the experiments|performed the literature search and drafted the manuscript|were responsible for the antifungal activity assay	performed the experiments	Performed the experiments	Investigation	YES
6320908	30513861	S.S.M.-O.	PLoS52	performed the experiments|performed the literature search and drafted the manuscript|were responsible for the antifungal activity assay	performed the literature search and drafted the manuscript	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6320908	30513861	S.S.M.-O.	PLoS52	performed the experiments|performed the literature search and drafted the manuscript|were responsible for the antifungal activity assay	were responsible for the antifungal activity assay	Performed the experiments	Investigation	YES
6320908	30513861	W.N.d.O.	PLoS52	performed the experiments|performed the literature search and drafted the manuscript|were responsible for the antifungal activity assay	performed the experiments	Performed the experiments	Investigation	YES
6320908	30513861	W.N.d.O.	PLoS52	performed the experiments|performed the literature search and drafted the manuscript|were responsible for the antifungal activity assay	performed the literature search and drafted the manuscript	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6320908	30513861	W.N.d.O.	PLoS52	performed the experiments|performed the literature search and drafted the manuscript|were responsible for the antifungal activity assay	were responsible for the antifungal activity assay	Performed the experiments	Investigation	YES
5415607	28523013	All authors	2	contributed to the design of the experiments and the writing of the manuscript	contributed to the design of the experiments and the writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5548261	28943631	A.H.	7	Supervision, editing and assistance with manuscript preparation	Supervision, editing and assistance with manuscript preparation	Wrote the paper	Supervision|Writing - Original Draft|Writing - Review & Editing	YES
5548261	28943631	K.M.	7	Primary author, conducted the systematic review and wrote the manuscript	Primary author, conducted the systematic review and wrote the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
4982113	27515508	AED	2	conceived and designed experiments|wrote the manuscript	conceived and designed experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4982113	27515508	AED	2	conceived and designed experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4982113	27515508	LKM	2	conceived and designed experiments|analyzed data|wrote the manuscript	conceived and designed experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4982113	27515508	LKM	2	conceived and designed experiments|analyzed data|wrote the manuscript	analyzed data	Analyzed the data	Formal analysis	YES
4982113	27515508	LKM	2	conceived and designed experiments|analyzed data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4982113	27515508	PC	2	designed snp markers and performed genotyping	designed snp markers and performed genotyping	Conceived and designed the experiments|Performed the experiments	Investigation	YES
4982113	27515508	QS	2	designed snp markers and performed genotyping	designed snp markers and performed genotyping	Conceived and designed the experiments|Performed the experiments	Investigation	YES
4982113	27515508	RS	2	conceived and designed experiments|executed experiments|analyzed data|wrote the manuscript	conceived and designed experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4982113	27515508	RS	2	conceived and designed experiments|executed experiments|analyzed data|wrote the manuscript	executed experiments	Performed the experiments	Investigation	YES
4982113	27515508	RS	2	conceived and designed experiments|executed experiments|analyzed data|wrote the manuscript	analyzed data	Analyzed the data	Formal analysis	YES
4982113	27515508	RS	2	conceived and designed experiments|executed experiments|analyzed data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4982113	27515508	WR	2	analyzed data|wrote the manuscript	analyzed data	Analyzed the data	Formal analysis	YES
4982113	27515508	WR	2	analyzed data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4395473	25875936	DK	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4395473	25875936	EWK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4395473	25875936	EWK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4395473	25875936	GSK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4395473	25875936	GSK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4395473	25875936	GSK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4395473	25875936	GSK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4395473	25875936	GSK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4395473	25875936	JAOR	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4395473	25875936	JAOR	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4395473	25875936	JAOR	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4395473	25875936	JF	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4395473	25875936	ROK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4395473	25875936	ROK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4395473	25875936	ROK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4395473	25875936	SF	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
6320914	30423956	G.M.	2	with valuable inputs from the rest of the authors	with valuable inputs from the rest of the authors	-	-	NO
6320914	30423956	S.S.	2	as well as the supporting information	as well as the supporting information	-	-	NO
5548262	28943622	A.Z.	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5548262	28943622	All authors	2	discussed, edited and approved the final version	discussed, edited and approved the final version	Wrote the paper	Writing - Review & Editing	YES
5548262	28943622	C.F.	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5548262	28943622	R.W.B.	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5415608	28523011	ED	2	planned the study, analyzed and interpreted the data, performed the experiments, conducted the statistical analysis, drafted the manuscript, and ultimately approved the version to be published	planned the study, analyzed and interpreted the data, performed the experiments, conducted the statistical analysis, drafted the manuscript, and ultimately approved the version to be published	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
5415608	28523011	ES	2	conducted experiments	conducted experiments	Performed the experiments	Investigation	YES
5415608	28523011	JH	2	planned the study, analyzed and interpreted the data, and drafted and edited the manuscript	planned the study, analyzed and interpreted the data, and drafted and edited the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5415608	28523011	RA	2	contributed to the design of the work and to data interpretation, and edited the manuscript	contributed to the design of the work and to data interpretation, and edited the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
5415608	28523011	SG	2	contributed to the conception of the work, analyzed the data, and edited the manuscript	contributed to the conception of the work, analyzed the data, and edited the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Resources|Writing - Review & Editing	YES
5415608	28523011	YH	2	performed experiments and contributed to the data analysis	performed experiments and contributed to the data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4982115	27515280	DL	2	were involved in the project design, data analysis and manuscript preparation	were involved in the project design, data analysis and manuscript preparation	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4982115	27515280	DR	2	contributed mouse olfactory epithelium	contributed mouse olfactory epithelium	-	-	NO
4982115	27515280	IK	2	was involved in the data analysis	was involved in the data analysis	Analyzed the data	Formal analysis	YES
4982115	27515280	JP	2	were responsible for obtaining human olfactory epithelium	were responsible for obtaining human olfactory epithelium	-	-	NO
4982115	27515280	OSN	2	single cell transcriptomics	single cell transcriptomics	Performed the experiments	Investigation	YES
4982115	27515280	PT	2	was responsible for the cdna preparation and qpcr	was responsible for the cdna preparation and qpcr	Performed the experiments	Investigation	YES
4982115	27515280	SF	2	contributed to the classification of the olfactory over expressed genes to gene families	contributed to the classification of the olfactory over expressed genes to gene families	-	-	NO
4982115	27515280	TO	2	were involved in the project design, data analysis and manuscript preparation	were involved in the project design, data analysis and manuscript preparation	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4982115	27515280	YG	2	were responsible for obtaining human olfactory epithelium	were responsible for obtaining human olfactory epithelium	-	-	NO
4396839	25874555	JE	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4396839	25874555	JE	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4396839	25874555	JE	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4396839	25874555	PB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4396839	25874555	PB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4396839	25874555	PB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4396839	25874555	SZ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4396839	25874555	SZ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4396839	25874555	SZ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4396839	25874555	TD	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4396839	25874555	TD	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4396839	25874555	TD	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4396839	25874555	TG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4396839	25874555	TG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4396839	25874555	TG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4396839	25874555	TG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6320920	30373197	A.B.	PLoS52	analyzed the data|contributed analysis tools	analyzed the data	Analyzed the data	Formal analysis	YES
6320920	30373197	A.B.	PLoS52	analyzed the data|contributed analysis tools	contributed analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
6320920	30373197	J.W.	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6320920	30373197	J.W.	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
6320920	30373197	J.W.	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
6320920	30373197	J.W.	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6320920	30373197	M.T.	PLoS52	analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
6320920	30373197	M.T.	PLoS52	analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5415610	28523008	JF	2	designed the research|wrote the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
5415610	28523008	JF	2	designed the research|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5415610	28523008	K-DP	2	performed the research, collected and analyzed the data	performed the research, collected and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5415610	28523008	QL	2	performed the research, collected and analyzed the data|wrote the manuscript	performed the research, collected and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5415610	28523008	QL	2	performed the research, collected and analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5415610	28523008	W-WL	2	performed the research, collected and analyzed the data	performed the research, collected and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5415610	28523008	Y-LP	2	designed the research|wrote the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
5415610	28523008	Y-LP	2	designed the research|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4982124	27515968	AAS	2	planned and supervised the study|contributed to the design of the analysis|contributed to the interpretation of the data and provided intellectual input|revised the manuscript	planned and supervised the study	Conceived and designed the experiments	Conceptualization|Supervision	YES
4982124	27515968	AAS	2	planned and supervised the study|contributed to the design of the analysis|contributed to the interpretation of the data and provided intellectual input|revised the manuscript	contributed to the design of the analysis	Conceived and designed the experiments	-	YES
4982124	27515968	AAS	2	planned and supervised the study|contributed to the design of the analysis|contributed to the interpretation of the data and provided intellectual input|revised the manuscript	contributed to the interpretation of the data and provided intellectual input	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
4982124	27515968	AAS	2	planned and supervised the study|contributed to the design of the analysis|contributed to the interpretation of the data and provided intellectual input|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4982124	27515968	CZ	2	contributed to the interpretation of the data and provided intellectual input|revised the manuscript	contributed to the interpretation of the data and provided intellectual input	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
4982124	27515968	CZ	2	contributed to the interpretation of the data and provided intellectual input|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4982124	27515968	DMM	2	performed the analysis of the data|drafted the manuscript|contributed to the interpretation of the data and provided intellectual input	performed the analysis of the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4982124	27515968	DMM	2	performed the analysis of the data|drafted the manuscript|contributed to the interpretation of the data and provided intellectual input	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4982124	27515968	DMM	2	performed the analysis of the data|drafted the manuscript|contributed to the interpretation of the data and provided intellectual input	contributed to the interpretation of the data and provided intellectual input	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
4982124	27515968	GCO	2	contributed to the design of the analysis	contributed to the design of the analysis	Conceived and designed the experiments	-	YES
4982124	27515968	LLSS	2	contributed to the design of the analysis|performed the analysis of the data|contributed to the interpretation of the data and provided intellectual input	contributed to the design of the analysis	Conceived and designed the experiments	-	YES
4982124	27515968	LLSS	2	contributed to the design of the analysis|performed the analysis of the data|contributed to the interpretation of the data and provided intellectual input	performed the analysis of the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4982124	27515968	LLSS	2	contributed to the design of the analysis|performed the analysis of the data|contributed to the interpretation of the data and provided intellectual input	contributed to the interpretation of the data and provided intellectual input	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
4982124	27515968	MAT	2	planned and supervised the study|contributed to the design of the analysis|contributed to the interpretation of the data and provided intellectual input|revised the manuscript	planned and supervised the study	Conceived and designed the experiments	Conceptualization|Supervision	YES
4982124	27515968	MAT	2	planned and supervised the study|contributed to the design of the analysis|contributed to the interpretation of the data and provided intellectual input|revised the manuscript	contributed to the design of the analysis	Conceived and designed the experiments	-	YES
4982124	27515968	MAT	2	planned and supervised the study|contributed to the design of the analysis|contributed to the interpretation of the data and provided intellectual input|revised the manuscript	contributed to the interpretation of the data and provided intellectual input	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
4982124	27515968	MAT	2	planned and supervised the study|contributed to the design of the analysis|contributed to the interpretation of the data and provided intellectual input|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4982124	27515968	NVS	2	carried out the syntenic analysis	carried out the syntenic analysis	Performed the experiments	Investigation	YES
4396840	25875427	EBB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4396840	25875427	EBB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4396840	25875427	EBB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4396840	25875427	GS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4396840	25875427	GS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4396840	25875427	GS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4396840	25875427	GS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4396840	25875427	LCLL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4396840	25875427	LCLL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4396840	25875427	LCLL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4396840	25875427	LCLL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4396840	25875427	MIDSX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4396840	25875427	MIDSX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4396840	25875427	MIDSX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4396840	25875427	MSAM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4396840	25875427	MTVR	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4396840	25875427	MTVR	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4396840	25875427	RMTH	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4396840	25875427	RTF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4396840	25875427	RTF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4396840	25875427	RTF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4396840	25875427	RTF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4396840	25875427	RTF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4396840	25875427	VCBB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4396840	25875427	VCBB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4396840	25875427	VCBB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4396840	25875427	VCBB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6320926	30545058	E.K.	2	conceived and designed research|conducted behavioral experiments|analyzed data|wrote the manuscript	conceived and designed research	Conceived and designed the experiments	Conceptualization|Methodology	YES
6320926	30545058	E.K.	2	conceived and designed research|conducted behavioral experiments|analyzed data|wrote the manuscript	conducted behavioral experiments	Performed the experiments	Investigation	YES
6320926	30545058	E.K.	2	conceived and designed research|conducted behavioral experiments|analyzed data|wrote the manuscript	analyzed data	Analyzed the data	Formal analysis	YES
6320926	30545058	E.K.	2	conceived and designed research|conducted behavioral experiments|analyzed data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6320926	30545058	E.P.	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
6320926	30545058	J.H.K.	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
6320926	30545058	K.S.	2	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
6320926	30545058	L.D.	2	conducted behavioral experiments|wrote the manuscript	conducted behavioral experiments	Performed the experiments	Investigation	YES
6320926	30545058	L.D.	2	conducted behavioral experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6320926	30545058	M.P.	2	conducted behavioral experiments	conducted behavioral experiments	Performed the experiments	Investigation	YES
6320926	30545058	P.O.	2	contributed new reagents or analytical tools	contributed new reagents or analytical tools	Contributed reagents/materials/analysis tools	Resources	YES
6320926	30545058	P.W.	2	contributed new reagents or analytical tools	contributed new reagents or analytical tools	Contributed reagents/materials/analysis tools	Resources	YES
5622333	28933370	All authors	2	contribute equally	contribute equally	-	-	NO
5415614	28523007	CL	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5415614	28523007	DP	PLoS52	finalized the manuscript	finalized the manuscript	Wrote the paper	Writing - Review & Editing	YES
5415614	28523007	FL	PLoS52	finalized the manuscript	finalized the manuscript	Wrote the paper	Writing - Review & Editing	YES
5415614	28523007	HY	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5415614	28523007	JP	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5415614	28523007	LH	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5415614	28523007	LY	PLoS52	finalized the manuscript	finalized the manuscript	Wrote the paper	Writing - Review & Editing	YES
5415614	28523007	WX	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5415614	28523007	XZ	PLoS52	conceived the project and designed the experiments	conceived the project and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5415614	28523007	XiaW	PLoS52	conceived the project and designed the experiments|performed the experiments|analyzed the data|finalized the manuscript	conceived the project and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5415614	28523007	XiaW	PLoS52	conceived the project and designed the experiments|performed the experiments|analyzed the data|finalized the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5415614	28523007	XiaW	PLoS52	conceived the project and designed the experiments|performed the experiments|analyzed the data|finalized the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5415614	28523007	XiaW	PLoS52	conceived the project and designed the experiments|performed the experiments|analyzed the data|finalized the manuscript	finalized the manuscript	Wrote the paper	Writing - Review & Editing	YES
5415614	28523007	XieW	PLoS52	finalized the manuscript	finalized the manuscript	Wrote the paper	Writing - Review & Editing	YES
5415614	28523007	YZ	PLoS52	conceived the project and designed the experiments|performed the experiments|analyzed the data|finalized the manuscript	conceived the project and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5415614	28523007	YZ	PLoS52	conceived the project and designed the experiments|performed the experiments|analyzed the data|finalized the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5415614	28523007	YZ	PLoS52	conceived the project and designed the experiments|performed the experiments|analyzed the data|finalized the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5415614	28523007	YZ	PLoS52	conceived the project and designed the experiments|performed the experiments|analyzed the data|finalized the manuscript	finalized the manuscript	Wrote the paper	Writing - Review & Editing	YES
5415614	28523007	ZL	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5415614	28523007	all authors	PLoS52	discussed the results and reviewed the manuscript	discussed the results and reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
4982125	27515663	LNM	2	conceived the study|wrote the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4982125	27515663	LNM	2	conceived the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4982125	27515663	PRJB	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4982125	27515663	SK	2	conceived the study|performed bioinformatics analysis and experimental validations|wrote the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4982125	27515663	SK	2	conceived the study|performed bioinformatics analysis and experimental validations|wrote the manuscript	performed bioinformatics analysis and experimental validations	Performed the experiments	Formal analysis|Investigation|Validation	YES
4982125	27515663	SK	2	conceived the study|performed bioinformatics analysis and experimental validations|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4396841	25875738	AT	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4396841	25875738	KH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4396841	25875738	KM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4396841	25875738	KY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4396841	25875738	KY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4396841	25875738	KY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4396841	25875738	KY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4396841	25875738	ME	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4396841	25875738	MI	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4396841	25875738	MI	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4396841	25875738	MI	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4396841	25875738	MI	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4396841	25875738	MY	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4396841	25875738	SY	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4396841	25875738	SY	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4396841	25875738	YI	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5415615	28523009	GR-C	PLoS52	designed the experiments|conducted the phenotypic analysis and qpcr|participated in the interpretation of results and critically reviewed the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5415615	28523009	GR-C	PLoS52	designed the experiments|conducted the phenotypic analysis and qpcr|participated in the interpretation of results and critically reviewed the manuscript	conducted the phenotypic analysis and qpcr	Performed the experiments	Investigation	YES
5415615	28523009	GR-C	PLoS52	designed the experiments|conducted the phenotypic analysis and qpcr|participated in the interpretation of results and critically reviewed the manuscript	participated in the interpretation of results and critically reviewed the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5415615	28523009	KM-A	PLoS52	designed the experiments|conducted the phenotypic analysis and qpcr|participated in the interpretation of results and critically reviewed the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5415615	28523009	KM-A	PLoS52	designed the experiments|conducted the phenotypic analysis and qpcr|participated in the interpretation of results and critically reviewed the manuscript	conducted the phenotypic analysis and qpcr	Performed the experiments	Investigation	YES
5415615	28523009	KM-A	PLoS52	designed the experiments|conducted the phenotypic analysis and qpcr|participated in the interpretation of results and critically reviewed the manuscript	participated in the interpretation of results and critically reviewed the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5415615	28523009	RA-V	PLoS52	provided the idea of the work|designed the experiments|participated in the interpretation of results and critically reviewed the manuscript|wrote the paper	provided the idea of the work	Conceived and designed the experiments	Conceptualization	YES
5415615	28523009	RA-V	PLoS52	provided the idea of the work|designed the experiments|participated in the interpretation of results and critically reviewed the manuscript|wrote the paper	designed the experiments	Conceived and designed the experiments	Methodology	YES
5415615	28523009	RA-V	PLoS52	provided the idea of the work|designed the experiments|participated in the interpretation of results and critically reviewed the manuscript|wrote the paper	participated in the interpretation of results and critically reviewed the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5415615	28523009	RA-V	PLoS52	provided the idea of the work|designed the experiments|participated in the interpretation of results and critically reviewed the manuscript|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6320943	30558371	B.A.M.	CRediT	Methodology|Formal analysis|Writing--original draft preparation|Writing--review & editing	Methodology	Performed the experiments	Methodology	YES
6320943	30558371	B.A.M.	CRediT	Methodology|Formal analysis|Writing--original draft preparation|Writing--review & editing	Formal analysis	Analyzed the data	Formal analysis	YES
6320943	30558371	B.A.M.	CRediT	Methodology|Formal analysis|Writing--original draft preparation|Writing--review & editing	Writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6320943	30558371	B.A.M.	CRediT	Methodology|Formal analysis|Writing--original draft preparation|Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6320943	30558371	D.W.A.B.	CRediT	Methodology|Writing--review & editing|Supervision	Methodology	Performed the experiments	Methodology	YES
6320943	30558371	D.W.A.B.	CRediT	Methodology|Writing--review & editing|Supervision	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6320943	30558371	D.W.A.B.	CRediT	Methodology|Writing--review & editing|Supervision	Supervision	-	Supervision	YES
6320943	30558371	M.A.P.	CRediT	Conceptualization|Methodology|Formal analysis|Writing--original draft preparation|Writing--review & editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6320943	30558371	M.A.P.	CRediT	Conceptualization|Methodology|Formal analysis|Writing--original draft preparation|Writing--review & editing	Methodology	Performed the experiments	Methodology	YES
6320943	30558371	M.A.P.	CRediT	Conceptualization|Methodology|Formal analysis|Writing--original draft preparation|Writing--review & editing	Formal analysis	Analyzed the data	Formal analysis	YES
6320943	30558371	M.A.P.	CRediT	Conceptualization|Methodology|Formal analysis|Writing--original draft preparation|Writing--review & editing	Writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6320943	30558371	M.A.P.	CRediT	Conceptualization|Methodology|Formal analysis|Writing--original draft preparation|Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6320943	30558371	R.A.K.	CRediT	Methodology|Formal analysis|Writing--review & editing	Methodology	Performed the experiments	Methodology	YES
6320943	30558371	R.A.K.	CRediT	Methodology|Formal analysis|Writing--review & editing	Formal analysis	Analyzed the data	Formal analysis	YES
6320943	30558371	R.A.K.	CRediT	Methodology|Formal analysis|Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6320943	30558371	U.B.K.	CRediT	Conceptualization|Methodology|Writing--review & editing|Supervision	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6320943	30558371	U.B.K.	CRediT	Conceptualization|Methodology|Writing--review & editing|Supervision	Methodology	Performed the experiments	Methodology	YES
6320943	30558371	U.B.K.	CRediT	Conceptualization|Methodology|Writing--review & editing|Supervision	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6320943	30558371	U.B.K.	CRediT	Conceptualization|Methodology|Writing--review & editing|Supervision	Supervision	-	Supervision	YES
6320943	30558371	Y.H.R.	CRediT	Methodology|Writing--review & editing|Supervision	Methodology	Performed the experiments	Methodology	YES
6320943	30558371	Y.H.R.	CRediT	Methodology|Writing--review & editing|Supervision	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6320943	30558371	Y.H.R.	CRediT	Methodology|Writing--review & editing|Supervision	Supervision	-	Supervision	YES
2660904	19272150	HJL	2	conceived of the study, participated in its design and contributed to drafting the manuscript	conceived of the study, participated in its design and contributed to drafting the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
2660904	19272150	LWR	2	conceived of the study, participated in its design and contributed to drafting the manuscript	conceived of the study, participated in its design and contributed to drafting the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
2660904	19272150	XL	2	collected the gc-ms data, performed data analysis, and contributed to drafting the manuscript	collected the gc-ms data, performed data analysis, and contributed to drafting the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4982134	27514375	BM	4	Laboratory analyses were carried out by|bioinformatic analysis was carried out by|Manuscript was written by	Laboratory analyses were carried out by	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4982134	27514375	BM	4	Laboratory analyses were carried out by|bioinformatic analysis was carried out by|Manuscript was written by	bioinformatic analysis was carried out by	Performed the experiments	Formal analysis|Investigation	YES
4982134	27514375	BM	4	Laboratory analyses were carried out by|bioinformatic analysis was carried out by|Manuscript was written by	Manuscript was written by	Wrote the paper	Writing - Original Draft	YES
4982134	27514375	CJC	4	bioinformatic analysis was carried out by	bioinformatic analysis was carried out by	Performed the experiments	Formal analysis|Investigation	YES
4982134	27514375	SB	4	This study was conceived and designed by|Sample collection was carried out by	This study was conceived and designed by	Conceived and designed the experiments	Conceptualization|Methodology	YES
4982134	27514375	SB	4	This study was conceived and designed by|Sample collection was carried out by	Sample collection was carried out by	Performed the experiments	Investigation	YES
4982134	27514375	SC	4	This study was conceived and designed by|Sample collection was carried out by	This study was conceived and designed by	Conceived and designed the experiments	Conceptualization|Methodology	YES
4982134	27514375	SC	4	This study was conceived and designed by|Sample collection was carried out by	Sample collection was carried out by	Performed the experiments	Investigation	YES
4396842	25875362	DB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4396842	25875362	DB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4396842	25875362	DB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4396842	25875362	FS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4396842	25875362	FS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4396842	25875362	YM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4396842	25875362	YM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4396842	25875362	YM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4396842	25875362	YM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6320949	30563123	C.F.	CRediT	Methodology|Investigation	Methodology	Performed the experiments	Methodology	YES
6320949	30563123	C.F.	CRediT	Methodology|Investigation	Investigation	Performed the experiments	Investigation	YES
6320949	30563123	E.D.	CRediT	Conceptualization|Writing-original draft preparation|Funding acquisition	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6320949	30563123	E.D.	CRediT	Conceptualization|Writing-original draft preparation|Funding acquisition	Writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
6320949	30563123	E.D.	CRediT	Conceptualization|Writing-original draft preparation|Funding acquisition	Funding acquisition	-	Funding acquisition	YES
6320949	30563123	K.J.H.A.	CRediT	Methodology|Investigation|Writing-review & editing	Methodology	Performed the experiments	Methodology	YES
6320949	30563123	K.J.H.A.	CRediT	Methodology|Investigation|Writing-review & editing	Investigation	Performed the experiments	Investigation	YES
6320949	30563123	K.J.H.A.	CRediT	Methodology|Investigation|Writing-review & editing	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6320949	30563123	M.E.M.	CRediT	Methodology|Investigation|Writing-review & editing	Methodology	Performed the experiments	Methodology	YES
6320949	30563123	M.E.M.	CRediT	Methodology|Investigation|Writing-review & editing	Investigation	Performed the experiments	Investigation	YES
6320949	30563123	M.E.M.	CRediT	Methodology|Investigation|Writing-review & editing	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6320949	30563123	R.J.	CRediT	Methodology|Investigation|Writing-review & editing	Methodology	Performed the experiments	Methodology	YES
6320949	30563123	R.J.	CRediT	Methodology|Investigation|Writing-review & editing	Investigation	Performed the experiments	Investigation	YES
6320949	30563123	R.J.	CRediT	Methodology|Investigation|Writing-review & editing	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
5415617	28523006	All authors	2	made substantial contributions to the conception, design or analysis of the work|contributed to drafting and revising the work, final approval of the version to be published, and are accountable for all aspects of the work, ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	made substantial contributions to the conception, design or analysis of the work	Conceived and designed the experiments	Conceptualization	YES
5415617	28523006	All authors	2	made substantial contributions to the conception, design or analysis of the work|contributed to drafting and revising the work, final approval of the version to be published, and are accountable for all aspects of the work, ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	contributed to drafting and revising the work, final approval of the version to be published, and are accountable for all aspects of the work, ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Wrote the paper	Writing - Original Draft	YES
2673221	19091086	RV	2	performed all the experiments, carried out the characterization of all the samples except the hrtem and prepared the original draft of the manuscript	performed all the experiments, carried out the characterization of all the samples except the hrtem and prepared the original draft of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
2673221	19091086	SE	2	supplied the coked injectors, initiated the work plan, provided feedback on the results and discussions and critically revised the manuscript for intellectual and written content	supplied the coked injectors, initiated the work plan, provided feedback on the results and discussions and critically revised the manuscript for intellectual and written content	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
4982135	27514516	GJ	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4982135	27514516	NT	PLoS52	designed research|analyzed data|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
4982135	27514516	NT	PLoS52	designed research|analyzed data|wrote the paper	analyzed data	Analyzed the data	Formal analysis	YES
4982135	27514516	NT	PLoS52	designed research|analyzed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4982135	27514516	QO	PLoS52	performed research|analyzed data|wrote the paper	performed research	Performed the experiments	Investigation	YES
4982135	27514516	QO	PLoS52	performed research|analyzed data|wrote the paper	analyzed data	Analyzed the data	Formal analysis	YES
4982135	27514516	QO	PLoS52	performed research|analyzed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3349208	22593689	Efthymia Vlachaki	2	performed literature review, analyzed and interpreted data, and wrote the paper|contributed equally to the paper	performed literature review, analyzed and interpreted data, and wrote the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
3349208	22593689	Efthymia Vlachaki	2	performed literature review, analyzed and interpreted data, and wrote the paper|contributed equally to the paper	contributed equally to the paper	-	-	NO
3349208	22593689	Elizabeth Ioannidou-Papagiannaki	2	analyzed and interpreted data and corrected the paper	analyzed and interpreted data and corrected the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
3349208	22593689	Ioannis Klonizakis	2	analyzed and interpreted data and corrected the paper	analyzed and interpreted data and corrected the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
3349208	22593689	Michael D. Diamantidis	2	performed literature review, analyzed and interpreted data, and wrote the paper|contributed equally to the paper	performed literature review, analyzed and interpreted data, and wrote the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
3349208	22593689	Michael D. Diamantidis	2	performed literature review, analyzed and interpreted data, and wrote the paper|contributed equally to the paper	contributed equally to the paper	-	-	NO
3349208	22593689	Philippos Klonizakis	2	performed literature review and analyzed and interpreted data	performed literature review and analyzed and interpreted data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3349208	22593689	Styliani Haralambidou-Vranitsa	2	analyzed and interpreted data and corrected the paper	analyzed and interpreted data and corrected the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
6320951	30279382	E.M.D.	CRediT	Conceptualization|Methodology|Investigation|Writing-original draft preparation|Writing-review & editing|Project administration|Funding acquisition	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6320951	30279382	E.M.D.	CRediT	Conceptualization|Methodology|Investigation|Writing-original draft preparation|Writing-review & editing|Project administration|Funding acquisition	Methodology	Performed the experiments	Methodology	YES
6320951	30279382	E.M.D.	CRediT	Conceptualization|Methodology|Investigation|Writing-original draft preparation|Writing-review & editing|Project administration|Funding acquisition	Investigation	Performed the experiments	Investigation	YES
6320951	30279382	E.M.D.	CRediT	Conceptualization|Methodology|Investigation|Writing-original draft preparation|Writing-review & editing|Project administration|Funding acquisition	Writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
6320951	30279382	E.M.D.	CRediT	Conceptualization|Methodology|Investigation|Writing-original draft preparation|Writing-review & editing|Project administration|Funding acquisition	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6320951	30279382	E.M.D.	CRediT	Conceptualization|Methodology|Investigation|Writing-original draft preparation|Writing-review & editing|Project administration|Funding acquisition	Project administration	-	Project administration	YES
6320951	30279382	E.M.D.	CRediT	Conceptualization|Methodology|Investigation|Writing-original draft preparation|Writing-review & editing|Project administration|Funding acquisition	Funding acquisition	-	Funding acquisition	YES
6320951	30279382	G.H.H.	CRediT	Methodology|Investigation|Writing-review & editing	Methodology	Performed the experiments	Methodology	YES
6320951	30279382	G.H.H.	CRediT	Methodology|Investigation|Writing-review & editing	Investigation	Performed the experiments	Investigation	YES
6320951	30279382	G.H.H.	CRediT	Methodology|Investigation|Writing-review & editing	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
4396843	25875253	HVW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4396843	25875253	HVW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4396843	25875253	HVW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4396843	25875253	NUNN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4396843	25875253	NUNN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4396843	25875253	NUNN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4396843	25875253	NUNN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4396843	25875253	NUNN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5750532	28961179	M.E.	2	conceived the manuscript and made critical revisions	conceived the manuscript and made critical revisions	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5415621	28523010	GS	7	analyzed the data|critical revision of manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5415621	28523010	GS	7	analyzed the data|critical revision of manuscript	critical revision of manuscript	Wrote the paper	Writing - Review & Editing	YES
5415621	28523010	KK	7	acquisition of data|analyzed the data	acquisition of data	Performed the experiments	Investigation	YES
5415621	28523010	KK	7	acquisition of data|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5415621	28523010	PC	7	conception and design of the work|performed the work|acquisition of data|analyzed the data|critical revision of manuscript|wrote the paper	conception and design of the work	Conceived and designed the experiments	Conceptualization	YES
5415621	28523010	PC	7	conception and design of the work|performed the work|acquisition of data|analyzed the data|critical revision of manuscript|wrote the paper	performed the work	Performed the experiments	Investigation	YES
5415621	28523010	PC	7	conception and design of the work|performed the work|acquisition of data|analyzed the data|critical revision of manuscript|wrote the paper	acquisition of data	Performed the experiments	Investigation	YES
5415621	28523010	PC	7	conception and design of the work|performed the work|acquisition of data|analyzed the data|critical revision of manuscript|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5415621	28523010	PC	7	conception and design of the work|performed the work|acquisition of data|analyzed the data|critical revision of manuscript|wrote the paper	critical revision of manuscript	Wrote the paper	Writing - Review & Editing	YES
5415621	28523010	PC	7	conception and design of the work|performed the work|acquisition of data|analyzed the data|critical revision of manuscript|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5415621	28523010	RA	7	critical revision of manuscript|wrote the paper	critical revision of manuscript	Wrote the paper	Writing - Review & Editing	YES
5415621	28523010	RA	7	critical revision of manuscript|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5415621	28523010	SS	7	conception and design of the work|performed the work|acquisition of data|analyzed the data|critical revision of manuscript|wrote the paper	conception and design of the work	Conceived and designed the experiments	Conceptualization	YES
5415621	28523010	SS	7	conception and design of the work|performed the work|acquisition of data|analyzed the data|critical revision of manuscript|wrote the paper	performed the work	Performed the experiments	Investigation	YES
5415621	28523010	SS	7	conception and design of the work|performed the work|acquisition of data|analyzed the data|critical revision of manuscript|wrote the paper	acquisition of data	Performed the experiments	Investigation	YES
5415621	28523010	SS	7	conception and design of the work|performed the work|acquisition of data|analyzed the data|critical revision of manuscript|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5415621	28523010	SS	7	conception and design of the work|performed the work|acquisition of data|analyzed the data|critical revision of manuscript|wrote the paper	critical revision of manuscript	Wrote the paper	Writing - Review & Editing	YES
5415621	28523010	SS	7	conception and design of the work|performed the work|acquisition of data|analyzed the data|critical revision of manuscript|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5415621	28523010	TS	7	conception and design of the work|critical revision of manuscript|wrote the paper	conception and design of the work	Conceived and designed the experiments	Conceptualization	YES
5415621	28523010	TS	7	conception and design of the work|critical revision of manuscript|wrote the paper	critical revision of manuscript	Wrote the paper	Writing - Review & Editing	YES
5415621	28523010	TS	7	conception and design of the work|critical revision of manuscript|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5415621	28523010	YK	7	performed the work|acquisition of data	performed the work	Performed the experiments	Investigation	YES
5415621	28523010	YK	7	performed the work|acquisition of data	acquisition of data	Performed the experiments	Investigation	YES
4982138	27520023	FB	2	is the principal investigator of the trophinoak project	is the principal investigator of the trophinoak project	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
4982138	27520023	HRM	2	carried out the research experiments|performed the bioinformatics and functional genomics analyses|wrote the manuscript	carried out the research experiments	Performed the experiments	Investigation	YES
4982138	27520023	HRM	2	carried out the research experiments|performed the bioinformatics and functional genomics analyses|wrote the manuscript	performed the bioinformatics and functional genomics analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4982138	27520023	HRM	2	carried out the research experiments|performed the bioinformatics and functional genomics analyses|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4982138	27520023	LF	2	performed the bioinformatics and functional genomics analyses	performed the bioinformatics and functional genomics analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4982138	27520023	LR	2	designed the research|wrote the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
4982138	27520023	LR	2	designed the research|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4982138	27520023	MB	2	performed the bioinformatics and functional genomics analyses	performed the bioinformatics and functional genomics analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4982138	27520023	MTT	2	designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
4982138	27520023	RM	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4982138	27520023	SH	2	designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
2681456	19193241	AAAK	2	contributed in the discussion of the results	contributed in the discussion of the results	-	-	NO
2681456	19193241	FDD	2	carried out the experimental parts	carried out the experimental parts	Performed the experiments	Investigation	YES
2681456	19193241	HAE	2	suggested the problem and carried out literature survey, undertaking the microanalysis, discussion of the results, writing the article and publication	suggested the problem and carried out literature survey, undertaking the microanalysis, discussion of the results, writing the article and publication	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6320955	30400376	A.Y.	CRediT	formal analysis|writing--review and editing|funding acquisition	formal analysis	Analyzed the data	Formal analysis	YES
6320955	30400376	A.Y.	CRediT	formal analysis|writing--review and editing|funding acquisition	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6320955	30400376	A.Y.	CRediT	formal analysis|writing--review and editing|funding acquisition	funding acquisition	-	Funding acquisition	YES
6320955	30400376	C.N.	CRediT	methodology|validation|formal analysis|investigation|data curation|writing--original draft preparation|visualization	methodology	Performed the experiments	Methodology	YES
6320955	30400376	C.N.	CRediT	methodology|validation|formal analysis|investigation|data curation|writing--original draft preparation|visualization	validation	Performed the experiments	Validation	YES
6320955	30400376	C.N.	CRediT	methodology|validation|formal analysis|investigation|data curation|writing--original draft preparation|visualization	formal analysis	Analyzed the data	Formal analysis	YES
6320955	30400376	C.N.	CRediT	methodology|validation|formal analysis|investigation|data curation|writing--original draft preparation|visualization	investigation	Performed the experiments	Investigation	YES
6320955	30400376	C.N.	CRediT	methodology|validation|formal analysis|investigation|data curation|writing--original draft preparation|visualization	data curation	Analyzed the data	Data curation	YES
6320955	30400376	C.N.	CRediT	methodology|validation|formal analysis|investigation|data curation|writing--original draft preparation|visualization	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6320955	30400376	C.N.	CRediT	methodology|validation|formal analysis|investigation|data curation|writing--original draft preparation|visualization	visualization	Analyzed the data	Visualization	YES
6320955	30400376	F.K.	CRediT	Conceptualization	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6320955	30400376	H.K.	CRediT	Conceptualization|methodology|validation|formal analysis|writing--original draft preparation|writing--review and editing|visualization|supervision|project administration	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6320955	30400376	H.K.	CRediT	Conceptualization|methodology|validation|formal analysis|writing--original draft preparation|writing--review and editing|visualization|supervision|project administration	methodology	Performed the experiments	Methodology	YES
6320955	30400376	H.K.	CRediT	Conceptualization|methodology|validation|formal analysis|writing--original draft preparation|writing--review and editing|visualization|supervision|project administration	validation	Performed the experiments	Validation	YES
6320955	30400376	H.K.	CRediT	Conceptualization|methodology|validation|formal analysis|writing--original draft preparation|writing--review and editing|visualization|supervision|project administration	formal analysis	Analyzed the data	Formal analysis	YES
6320955	30400376	H.K.	CRediT	Conceptualization|methodology|validation|formal analysis|writing--original draft preparation|writing--review and editing|visualization|supervision|project administration	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6320955	30400376	H.K.	CRediT	Conceptualization|methodology|validation|formal analysis|writing--original draft preparation|writing--review and editing|visualization|supervision|project administration	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6320955	30400376	H.K.	CRediT	Conceptualization|methodology|validation|formal analysis|writing--original draft preparation|writing--review and editing|visualization|supervision|project administration	visualization	Analyzed the data	Visualization	YES
6320955	30400376	H.K.	CRediT	Conceptualization|methodology|validation|formal analysis|writing--original draft preparation|writing--review and editing|visualization|supervision|project administration	supervision	-	Supervision	YES
6320955	30400376	H.K.	CRediT	Conceptualization|methodology|validation|formal analysis|writing--original draft preparation|writing--review and editing|visualization|supervision|project administration	project administration	-	Project administration	YES
6320955	30400376	K.F.	CRediT	resources	resources	Contributed reagents/materials/analysis tools	Resources	YES
6320955	30400376	Tomoko Suzuki	CRediT	formal analysis|investigation|data curation	formal analysis	Analyzed the data	Formal analysis	YES
6320955	30400376	Tomoko Suzuki	CRediT	formal analysis|investigation|data curation	investigation	Performed the experiments	Investigation	YES
6320955	30400376	Tomoko Suzuki	CRediT	formal analysis|investigation|data curation	data curation	Analyzed the data	Data curation	YES
6320955	30400376	Toshiyasu Sakane	CRediT	formal analysis	formal analysis	Analyzed the data	Formal analysis	YES
6320955	30400376	Y.-s.Q.	CRediT	methodology|validation|investigation	methodology	Performed the experiments	Methodology	YES
6320955	30400376	Y.-s.Q.	CRediT	methodology|validation|investigation	validation	Performed the experiments	Validation	YES
6320955	30400376	Y.-s.Q.	CRediT	methodology|validation|investigation	investigation	Performed the experiments	Investigation	YES
4396850	25875842	AM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4396850	25875842	AM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4396850	25875842	AM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4396850	25875842	FT	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4396850	25875842	FT	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4396850	25875842	KM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4396850	25875842	KM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4396850	25875842	KM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4396850	25875842	KM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4396850	25875842	MA	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4396850	25875842	MK	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4396850	25875842	MK	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4396850	25875842	MK	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4396850	25875842	RA	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4396850	25875842	SA	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4396850	25875842	SA	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4396850	25875842	SM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2715391	19570217	Aifang Li	2	carried out nearly all of the laboratory work	carried out nearly all of the laboratory work	Performed the experiments	Investigation	YES
2715391	19570217	All authors	2	contributed to the experimental design	contributed to the experimental design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
2715391	19570217	Baohui Zhou	2	carried out nearly all of the laboratory work	carried out nearly all of the laboratory work	Performed the experiments	Investigation	YES
2715391	19570217	Chaokun Qiu	2	deal with the data analysis	deal with the data analysis	Analyzed the data	Formal analysis	YES
2715391	19570217	Hongmin Ren	2	deal with the data analysis	deal with the data analysis	Analyzed the data	Formal analysis	YES
2715391	19570217	Xiaoyu Liu	2	focused on the experiment design and contributed to drafting the manuscript	focused on the experiment design and contributed to drafting the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5416745	28523005	EB	PLoS52	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5416745	28523005	MV	PLoS52	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5416745	28523005	PZ	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5416745	28523005	all other authors	PLoS52	provided editorial contributions	provided editorial contributions	-	-	NO
4385602	25874210	Jung-Feng Hsieh	2	contributed equally to this work	contributed equally to this work	-	-	NO
4385602	25874210	Ken-Lin Chang	2	contributed equally to this work	contributed equally to this work	-	-	NO
4385602	25874210	Shui-Tein Chen	2	contributed equally to this work	contributed equally to this work	-	-	NO
4982142	27516089	AG	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
4982142	27516089	AM	2	developed the pipeline and performed sequencing data analysis|designed the study|wrote the manuscript	developed the pipeline and performed sequencing data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4982142	27516089	AM	2	developed the pipeline and performed sequencing data analysis|designed the study|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
4982142	27516089	AM	2	developed the pipeline and performed sequencing data analysis|designed the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4982142	27516089	AP	2	performed molecular cytogenetics experiments	performed molecular cytogenetics experiments	Performed the experiments	Investigation	YES
4982142	27516089	All authors	2	have revised and corrected the manuscript	have revised and corrected the manuscript	Wrote the paper	Writing - Review & Editing	YES
4982142	27516089	DL	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
4982142	27516089	EC	2	performed high-throughput sequencing	performed high-throughput sequencing	Performed the experiments	Investigation	YES
4982142	27516089	FY	2	performed chromosome sorting	performed chromosome sorting	Performed the experiments	Investigation	YES
4982142	27516089	IK	2	developed the pipeline and performed sequencing data analysis	developed the pipeline and performed sequencing data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4982142	27516089	MFS	2	performed chromosome sorting	performed chromosome sorting	Performed the experiments	Investigation	YES
4982142	27516089	NV	2	performed molecular cytogenetics experiments	performed molecular cytogenetics experiments	Performed the experiments	Investigation	YES
4982142	27516089	PO	2	performed chromosome sorting	performed chromosome sorting	Performed the experiments	Investigation	YES
4982142	27516089	SO	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
4982142	27516089	VT	2	performed chromosome sorting|performed molecular cytogenetics experiments|designed the study	performed chromosome sorting	Performed the experiments	Investigation	YES
4982142	27516089	VT	2	performed chromosome sorting|performed molecular cytogenetics experiments|designed the study	performed molecular cytogenetics experiments	Performed the experiments	Investigation	YES
4982142	27516089	VT	2	performed chromosome sorting|performed molecular cytogenetics experiments|designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
6320969	30513856	A.A.d.S.-J.	PLoS52	conceived and designed the experiments|wrote and refined the final version of the manuscript for publication	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6320969	30513856	A.A.d.S.-J.	PLoS52	conceived and designed the experiments|wrote and refined the final version of the manuscript for publication	wrote and refined the final version of the manuscript for publication	Wrote the paper	Writing - Original Draft	YES
6320969	30513856	A.M.C.	PLoS52	contributed to the discussion and revised the manuscript	contributed to the discussion and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
6320969	30513856	E.M.d.S.S.	PLoS52	contributed to the discussion and revised the manuscript	contributed to the discussion and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
6320969	30513856	E.S.T.d.E.	PLoS52	contributed to the discussion and revised the manuscript	contributed to the discussion and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
6320969	30513856	K.J.S.F.	PLoS52	conceived and designed the experiments|contributed to the discussion and revised the manuscript|wrote and refined the final version of the manuscript for publication	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6320969	30513856	K.J.S.F.	PLoS52	conceived and designed the experiments|contributed to the discussion and revised the manuscript|wrote and refined the final version of the manuscript for publication	contributed to the discussion and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
6320969	30513856	K.J.S.F.	PLoS52	conceived and designed the experiments|contributed to the discussion and revised the manuscript|wrote and refined the final version of the manuscript for publication	wrote and refined the final version of the manuscript for publication	Wrote the paper	Writing - Original Draft	YES
6320969	30513856	M.d.F.F.-P.	PLoS52	contributed to the discussion and revised the manuscript	contributed to the discussion and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
6320969	30513856	NP	PLoS52	preparation and wrote this part	preparation and wrote this part	Wrote the paper	Writing - Original Draft	YES
6320969	30513856	P.R.L.M.	PLoS52	contributed to the discussion and revised the manuscript	contributed to the discussion and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
6320969	30513856	R.d.C.F.	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6320969	30513856	T.L.C.L.	PLoS52	conceived and designed the experiments|contributed to the discussion and revised the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6320969	30513856	T.L.C.L.	PLoS52	conceived and designed the experiments|contributed to the discussion and revised the manuscript	contributed to the discussion and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
2719632	19604409	AY	2	performed data analysis, and contributed to drafting the manuscript	performed data analysis, and contributed to drafting the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
2719632	19604409	EF	2	collected the nmr data	collected the nmr data	Performed the experiments	Investigation	YES
2719632	19604409	HO	2	performed data analysis, and contributed to drafting the manuscript	performed data analysis, and contributed to drafting the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
2719632	19604409	JK	2	collected the nmr data	collected the nmr data	Performed the experiments	Investigation	YES
2719632	19604409	NK	2	performed data analysis, and contributed to drafting the manuscript	performed data analysis, and contributed to drafting the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
2719632	19604409	NS	2	conceived of the study, participated in its design and contributed to drafting the manuscript	conceived of the study, participated in its design and contributed to drafting the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
2719632	19604409	SO	2	conceived of the study, participated in its design and contributed to drafting the manuscript	conceived of the study, participated in its design and contributed to drafting the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
4396851	25875370	JNC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4396851	25875370	JNC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4396851	25875370	JNC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4396851	25875370	JNC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4396851	25875370	JRL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4396851	25875370	JRL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4396851	25875370	JRL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4396851	25875370	SHL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4396851	25875370	SHL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4396851	25875370	SHL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4396851	25875370	WSS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4396851	25875370	WSS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4396851	25875370	WSS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5416839	28523012	CT	PLoS52	performed the experiments|analyzed the data and prepared figures and graphs	performed the experiments	Performed the experiments	Investigation	YES
5416839	28523012	CT	PLoS52	performed the experiments|analyzed the data and prepared figures and graphs	analyzed the data and prepared figures and graphs	Analyzed the data	Formal analysis|Visualization	YES
5416839	28523012	EB	PLoS52	performed the experiments|analyzed the data and prepared figures and graphs	performed the experiments	Performed the experiments	Investigation	YES
5416839	28523012	EB	PLoS52	performed the experiments|analyzed the data and prepared figures and graphs	analyzed the data and prepared figures and graphs	Analyzed the data	Formal analysis|Visualization	YES
5416839	28523012	MT	PLoS52	contributed reagents, materials, and analysis tools	contributed reagents, materials, and analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5416839	28523012	NK	PLoS52	performed the experiments|analyzed the data and prepared figures and graphs|contributed reagents, materials, and analysis tools|prepared the manuscript, and all the members contributed extensively to its finalization	performed the experiments	Performed the experiments	Investigation	YES
5416839	28523012	NK	PLoS52	performed the experiments|analyzed the data and prepared figures and graphs|contributed reagents, materials, and analysis tools|prepared the manuscript, and all the members contributed extensively to its finalization	analyzed the data and prepared figures and graphs	Analyzed the data	Formal analysis|Visualization	YES
5416839	28523012	NK	PLoS52	performed the experiments|analyzed the data and prepared figures and graphs|contributed reagents, materials, and analysis tools|prepared the manuscript, and all the members contributed extensively to its finalization	contributed reagents, materials, and analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5416839	28523012	NK	PLoS52	performed the experiments|analyzed the data and prepared figures and graphs|contributed reagents, materials, and analysis tools|prepared the manuscript, and all the members contributed extensively to its finalization	prepared the manuscript, and all the members contributed extensively to its finalization	Wrote the paper	Writing - Original Draft	YES
5416839	28523012	NL	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data and prepared figures and graphs|prepared the manuscript, and all the members contributed extensively to its finalization	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5416839	28523012	NL	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data and prepared figures and graphs|prepared the manuscript, and all the members contributed extensively to its finalization	performed the experiments	Performed the experiments	Investigation	YES
5416839	28523012	NL	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data and prepared figures and graphs|prepared the manuscript, and all the members contributed extensively to its finalization	analyzed the data and prepared figures and graphs	Analyzed the data	Formal analysis|Visualization	YES
5416839	28523012	NL	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data and prepared figures and graphs|prepared the manuscript, and all the members contributed extensively to its finalization	prepared the manuscript, and all the members contributed extensively to its finalization	Wrote the paper	Writing - Original Draft	YES
5416839	28523012	WY	PLoS52	conceived and designed the experiments|analyzed the data and prepared figures and graphs|prepared the manuscript, and all the members contributed extensively to its finalization	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5416839	28523012	WY	PLoS52	conceived and designed the experiments|analyzed the data and prepared figures and graphs|prepared the manuscript, and all the members contributed extensively to its finalization	analyzed the data and prepared figures and graphs	Analyzed the data	Formal analysis|Visualization	YES
5416839	28523012	WY	PLoS52	conceived and designed the experiments|analyzed the data and prepared figures and graphs|prepared the manuscript, and all the members contributed extensively to its finalization	prepared the manuscript, and all the members contributed extensively to its finalization	Wrote the paper	Writing - Original Draft	YES
4982197	27515403	BY	2	participated in the design of the study, performed the statistical analysis and drafted the manuscript	participated in the design of the study, performed the statistical analysis and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4982197	27515403	HFZ	2	conceived of the study, and participated in its design and coordination	conceived of the study, and participated in its design and coordination	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
4982197	27515403	HX	2	carried out the animal experiment	carried out the animal experiment	Performed the experiments	Investigation	YES
4982197	27515403	LC	2	participated in the data analysis and helped to draft the manuscript	participated in the data analysis and helped to draft the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4982197	27515403	RNS	2	conceived of the study, and participated in its design and coordination	conceived of the study, and participated in its design and coordination	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
4982197	27515403	RQZ	2	carried out the animal experiment	carried out the animal experiment	Performed the experiments	Investigation	YES
5750535	29064392	Alessandro Pingitore	PLoS52	enrolled the subjects, and collected all clinical data	enrolled the subjects, and collected all clinical data	Performed the experiments	Investigation	YES
5750535	29064392	Cristina Vassalle	PLoS52	conceived and designed the experiments|analyzed the data and wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5750535	29064392	Cristina Vassalle	PLoS52	conceived and designed the experiments|analyzed the data and wrote the paper	analyzed the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5750535	29064392	Laura Sabatino	PLoS52	performed the analysis|revised the english style	performed the analysis	Performed the experiments	Investigation	YES
5750535	29064392	Laura Sabatino	PLoS52	performed the analysis|revised the english style	revised the english style	Wrote the paper	Writing - Review & Editing	YES
5750535	29064392	Maristella Maltinti	PLoS52	performed the analysis	performed the analysis	Performed the experiments	Investigation	YES
5750535	29064392	Pietro Di Cecco	PLoS52	performed the analysis	performed the analysis	Performed the experiments	Investigation	YES
5750535	29064392	Rudina Nreu	PLoS52	performed the analysis	performed the analysis	Performed the experiments	Investigation	YES
5750535	29064392	Silvia Maffei	PLoS52	enrolled the subjects, and collected all clinical data	enrolled the subjects, and collected all clinical data	Performed the experiments	Investigation	YES
5750535	29064392	all authors	PLoS52	reviewed and approved the final version of the manuscript	reviewed and approved the final version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
6320972	30469356	Abdullah Mayati	CRediT	Conceptualization|formal analysis|investigation|writing--review and editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6320972	30469356	Abdullah Mayati	CRediT	Conceptualization|formal analysis|investigation|writing--review and editing	formal analysis	Analyzed the data	Formal analysis	YES
6320972	30469356	Abdullah Mayati	CRediT	Conceptualization|formal analysis|investigation|writing--review and editing	investigation	Performed the experiments	Investigation	YES
6320972	30469356	Abdullah Mayati	CRediT	Conceptualization|formal analysis|investigation|writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6320972	30469356	Amelie Moreau	CRediT	Conceptualization|writing--review and editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6320972	30469356	Amelie Moreau	CRediT	Conceptualization|writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6320972	30469356	C.D.	CRediT	Conceptualization	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6320972	30469356	E.J.	CRediT	formal analysis|investigation	formal analysis	Analyzed the data	Formal analysis	YES
6320972	30469356	E.J.	CRediT	formal analysis|investigation	investigation	Performed the experiments	Investigation	YES
6320972	30469356	M.F.-J.	CRediT	investigation	investigation	Performed the experiments	Investigation	YES
6320972	30469356	O.F.	CRediT	Conceptualization|methodology|formal analysis|writing--original draft preparation|writing--review and editing|supervision|project administration	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6320972	30469356	O.F.	CRediT	Conceptualization|methodology|formal analysis|writing--original draft preparation|writing--review and editing|supervision|project administration	methodology	Performed the experiments	Methodology	YES
6320972	30469356	O.F.	CRediT	Conceptualization|methodology|formal analysis|writing--original draft preparation|writing--review and editing|supervision|project administration	formal analysis	Analyzed the data	Formal analysis	YES
6320972	30469356	O.F.	CRediT	Conceptualization|methodology|formal analysis|writing--original draft preparation|writing--review and editing|supervision|project administration	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6320972	30469356	O.F.	CRediT	Conceptualization|methodology|formal analysis|writing--original draft preparation|writing--review and editing|supervision|project administration	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6320972	30469356	O.F.	CRediT	Conceptualization|methodology|formal analysis|writing--original draft preparation|writing--review and editing|supervision|project administration	supervision	-	Supervision	YES
6320972	30469356	O.F.	CRediT	Conceptualization|methodology|formal analysis|writing--original draft preparation|writing--review and editing|supervision|project administration	project administration	-	Project administration	YES
6320972	30469356	Y.P.	CRediT	Conceptualization|writing--review and editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6320972	30469356	Y.P.	CRediT	Conceptualization|writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
2739206	19689800	BLP	2	collected nmr spectra and wrote these sections of the paper	collected nmr spectra and wrote these sections of the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
2739206	19689800	GPH	2	wrote the raman methods and results sections	wrote the raman methods and results sections	Performed the experiments|Wrote the paper	Writing - Original Draft	YES
2739206	19689800	JDK	2	carried out the quantum mechanical calculations and wrote these portions of the paper	carried out the quantum mechanical calculations and wrote these portions of the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
2739206	19689800	PJ	2	collected the raman spectra	collected the raman spectra	Performed the experiments	Investigation	YES
6320973	30282921	All authors	PLoS52	have reviewed and approved the final version of the manuscript	have reviewed and approved the final version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
6320973	30282921	C.T.	PLoS52	designed and performed the experiments	designed and performed the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6320973	30282921	J.-X.W.	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
6320973	30282921	W.L.	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
6320973	30282921	X.-Q.S.	PLoS52	designed and performed the experiments	designed and performed the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5418227	28529518	AK	7	Planned, supervised the research and contributed in preparing the manuscript	Planned, supervised the research and contributed in preparing the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Supervision|Writing - Original Draft	YES
5418227	28529518	AR	7	Helped in statistical analysis	Helped in statistical analysis	Analyzed the data	Formal analysis	YES
5418227	28529518	BR	7	developed ril population and manuscript review	developed ril population and manuscript review	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5418227	28529518	FJ	7	Supervised the research and manuscript review	Supervised the research and manuscript review	Wrote the paper	Supervision|Writing - Review & Editing	YES
5418227	28529518	GaA	7	Helped in phenotyping the ril population	Helped in phenotyping the ril population	Performed the experiments	Investigation	YES
5418227	28529518	GhA	7	Supervised the research and manuscript review	Supervised the research and manuscript review	Wrote the paper	Supervision|Writing - Review & Editing	YES
5418227	28529518	KA	7	Executed the experiments, carried out statistical analysis and prepared manuscript	Executed the experiments, carried out statistical analysis and prepared manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5418227	28529518	KH	7	Helped in phenotyping the ril population	Helped in phenotyping the ril population	Performed the experiments	Investigation	YES
5418227	28529518	KR	7	Supervised the research and manuscript review	Supervised the research and manuscript review	Wrote the paper	Supervision|Writing - Review & Editing	YES
5418227	28529518	RD	7	Helped in statistical analysis	Helped in statistical analysis	Analyzed the data	Formal analysis	YES
5418227	28529518	RP	7	Executed the experiments, carried out statistical analysis and prepared manuscript	Executed the experiments, carried out statistical analysis and prepared manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5418227	28529518	SD	7	Supervised the research and manuscript review	Supervised the research and manuscript review	Wrote the paper	Supervision|Writing - Review & Editing	YES
5418227	28529518	SM	7	Helped in phenotyping the ril population	Helped in phenotyping the ril population	Performed the experiments	Investigation	YES
5418227	28529518	TH	7	developed ril population and manuscript review	developed ril population and manuscript review	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5418227	28529518	TR	7	Supervised the research and manuscript review	Supervised the research and manuscript review	Wrote the paper	Supervision|Writing - Review & Editing	YES
2739844	19664263	GK	2	carried out the molecular docking studies	carried out the molecular docking studies	Performed the experiments	Investigation	YES
2739844	19664263	SKU	2	conceived of the study, collected the nmr data, processed and analysed all nmr spectra, discussion of the results and wrote the manuscript	conceived of the study, collected the nmr data, processed and analysed all nmr spectra, discussion of the results and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Data curation|Formal analysis|Investigation|Writing - Original Draft	YES
4982198	27519859	AB	2	performed rt-qpcr analysis, contributed to bioinformatics analysis	performed rt-qpcr analysis, contributed to bioinformatics analysis	Performed the experiments	Formal analysis|Investigation	YES
4982198	27519859	All authors	2	contributed to data analysis	contributed to data analysis	Analyzed the data	Formal analysis	YES
4982198	27519859	DMA	2	designed the study concept, coordinated the research and supervised experiments, performed data analysis and wrote the manuscript	designed the study concept, coordinated the research and supervised experiments, performed data analysis and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Project administration|Supervision|Writing - Original Draft	YES
4982198	27519859	JR	2	contributed to lam of frozen roots	contributed to lam of frozen roots	-	-	NO
4982198	27519859	MKen	2	carried out the majority of experiments, performed lam from wax-embedded tissues, bioinformatics, expression analysis, and confocal based analysis	carried out the majority of experiments, performed lam from wax-embedded tissues, bioinformatics, expression analysis, and confocal based analysis	Performed the experiments	Formal analysis|Investigation	YES
4982198	27519859	MKlim	2	performed lam of frozen leaves	performed lam of frozen leaves	Performed the experiments	Investigation	YES
4982198	27519859	PS	2	performed bioinformatics analyses	performed bioinformatics analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4982198	27519859	SB	2	contributed to lam of frozen roots and leaves	contributed to lam of frozen roots and leaves	-	-	NO
4396853	25874766	CAOS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4396853	25874766	CAR	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4396853	25874766	CAR	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4396853	25874766	CS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4396853	25874766	CS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4396853	25874766	CS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4396853	25874766	ED	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4396853	25874766	KM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4396853	25874766	KM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4396853	25874766	KM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4396853	25874766	KM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4396853	25874766	KM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4396853	25874766	PWOT	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4396853	25874766	PWOT	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4396853	25874766	RPR	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4396853	25874766	RPR	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4396853	25874766	RPR	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2758878	19740416	HS	2	developed the nomenclature, wrote the text, and contributed figures 2 to 4	developed the nomenclature, wrote the text, and contributed figures 2 to 4	Wrote the paper	Visualization|Writing - Original Draft	YES
5418335	28529520	DS	2	wrote the manuscript with input by the other authors	wrote the manuscript with input by the other authors	Wrote the paper	Writing - Original Draft	YES
5418335	28529520	GK	2	helped with embryo preparations and with microscopy in general	helped with embryo preparations and with microscopy in general	Performed the experiments	Investigation	YES
5418335	28529520	IL	2	carried out most of the experiments conducted herein	carried out most of the experiments conducted herein	Performed the experiments	Investigation	YES
5418335	28529520	JS	2	conceived the project and supervised its progress|wrote the manuscript with input by the other authors	conceived the project and supervised its progress	Conceived and designed the experiments	Conceptualization|Supervision	YES
5418335	28529520	JS	2	conceived the project and supervised its progress|wrote the manuscript with input by the other authors	wrote the manuscript with input by the other authors	Wrote the paper	Writing - Original Draft	YES
4385606	25874201	Haiqi Lu	2	contributed equally to the work	contributed equally to the work	-	-	NO
4385606	25874201	Huiyin Lan	2	contributed equally to the work	contributed equally to the work	-	-	NO
6320981	30423941	A.A.	CRediT	Conceptualization|Software|Validation|Formal analysis|Investigation|Resources|Writing--original draft preparation|Writing--review & editing|Supervision|Project administration|Funding acquisition	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6320981	30423941	A.A.	CRediT	Conceptualization|Software|Validation|Formal analysis|Investigation|Resources|Writing--original draft preparation|Writing--review & editing|Supervision|Project administration|Funding acquisition	Software	Contributed reagents/materials/analysis tools	Software	YES
6320981	30423941	A.A.	CRediT	Conceptualization|Software|Validation|Formal analysis|Investigation|Resources|Writing--original draft preparation|Writing--review & editing|Supervision|Project administration|Funding acquisition	Validation	Performed the experiments	Validation	YES
6320981	30423941	A.A.	CRediT	Conceptualization|Software|Validation|Formal analysis|Investigation|Resources|Writing--original draft preparation|Writing--review & editing|Supervision|Project administration|Funding acquisition	Formal analysis	Analyzed the data	Formal analysis	YES
6320981	30423941	A.A.	CRediT	Conceptualization|Software|Validation|Formal analysis|Investigation|Resources|Writing--original draft preparation|Writing--review & editing|Supervision|Project administration|Funding acquisition	Investigation	Performed the experiments	Investigation	YES
6320981	30423941	A.A.	CRediT	Conceptualization|Software|Validation|Formal analysis|Investigation|Resources|Writing--original draft preparation|Writing--review & editing|Supervision|Project administration|Funding acquisition	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6320981	30423941	A.A.	CRediT	Conceptualization|Software|Validation|Formal analysis|Investigation|Resources|Writing--original draft preparation|Writing--review & editing|Supervision|Project administration|Funding acquisition	Writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6320981	30423941	A.A.	CRediT	Conceptualization|Software|Validation|Formal analysis|Investigation|Resources|Writing--original draft preparation|Writing--review & editing|Supervision|Project administration|Funding acquisition	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6320981	30423941	A.A.	CRediT	Conceptualization|Software|Validation|Formal analysis|Investigation|Resources|Writing--original draft preparation|Writing--review & editing|Supervision|Project administration|Funding acquisition	Supervision	-	Supervision	YES
6320981	30423941	A.A.	CRediT	Conceptualization|Software|Validation|Formal analysis|Investigation|Resources|Writing--original draft preparation|Writing--review & editing|Supervision|Project administration|Funding acquisition	Project administration	-	Project administration	YES
6320981	30423941	A.A.	CRediT	Conceptualization|Software|Validation|Formal analysis|Investigation|Resources|Writing--original draft preparation|Writing--review & editing|Supervision|Project administration|Funding acquisition	Funding acquisition	-	Funding acquisition	YES
6320981	30423941	G.V.	CRediT	Conceptualization|Methodology|Validation|Investigation|Data curation|Writing--original draft preparation	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6320981	30423941	G.V.	CRediT	Conceptualization|Methodology|Validation|Investigation|Data curation|Writing--original draft preparation	Methodology	Performed the experiments	Methodology	YES
6320981	30423941	G.V.	CRediT	Conceptualization|Methodology|Validation|Investigation|Data curation|Writing--original draft preparation	Validation	Performed the experiments	Validation	YES
6320981	30423941	G.V.	CRediT	Conceptualization|Methodology|Validation|Investigation|Data curation|Writing--original draft preparation	Investigation	Performed the experiments	Investigation	YES
6320981	30423941	G.V.	CRediT	Conceptualization|Methodology|Validation|Investigation|Data curation|Writing--original draft preparation	Data curation	Analyzed the data	Data curation	YES
6320981	30423941	G.V.	CRediT	Conceptualization|Methodology|Validation|Investigation|Data curation|Writing--original draft preparation	Writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6320981	30423941	I.T.	CRediT	Conceptualization|Methodology|Validation|Investigation|Resources|Writing--original draft preparation|Writing--review & editing|Supervision|Project administration|Funding acquisition	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6320981	30423941	I.T.	CRediT	Conceptualization|Methodology|Validation|Investigation|Resources|Writing--original draft preparation|Writing--review & editing|Supervision|Project administration|Funding acquisition	Methodology	Performed the experiments	Methodology	YES
6320981	30423941	I.T.	CRediT	Conceptualization|Methodology|Validation|Investigation|Resources|Writing--original draft preparation|Writing--review & editing|Supervision|Project administration|Funding acquisition	Validation	Performed the experiments	Validation	YES
6320981	30423941	I.T.	CRediT	Conceptualization|Methodology|Validation|Investigation|Resources|Writing--original draft preparation|Writing--review & editing|Supervision|Project administration|Funding acquisition	Investigation	Performed the experiments	Investigation	YES
6320981	30423941	I.T.	CRediT	Conceptualization|Methodology|Validation|Investigation|Resources|Writing--original draft preparation|Writing--review & editing|Supervision|Project administration|Funding acquisition	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6320981	30423941	I.T.	CRediT	Conceptualization|Methodology|Validation|Investigation|Resources|Writing--original draft preparation|Writing--review & editing|Supervision|Project administration|Funding acquisition	Writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6320981	30423941	I.T.	CRediT	Conceptualization|Methodology|Validation|Investigation|Resources|Writing--original draft preparation|Writing--review & editing|Supervision|Project administration|Funding acquisition	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6320981	30423941	I.T.	CRediT	Conceptualization|Methodology|Validation|Investigation|Resources|Writing--original draft preparation|Writing--review & editing|Supervision|Project administration|Funding acquisition	Supervision	-	Supervision	YES
6320981	30423941	I.T.	CRediT	Conceptualization|Methodology|Validation|Investigation|Resources|Writing--original draft preparation|Writing--review & editing|Supervision|Project administration|Funding acquisition	Project administration	-	Project administration	YES
6320981	30423941	I.T.	CRediT	Conceptualization|Methodology|Validation|Investigation|Resources|Writing--original draft preparation|Writing--review & editing|Supervision|Project administration|Funding acquisition	Funding acquisition	-	Funding acquisition	YES
6320981	30423941	L.D.M.	CRediT	Investigation|Data curation	Investigation	Performed the experiments	Investigation	YES
6320981	30423941	L.D.M.	CRediT	Investigation|Data curation	Data curation	Analyzed the data	Data curation	YES
6320981	30423941	M.A.C.	CRediT	Investigation|Visualization|Supervision	Investigation	Performed the experiments	Investigation	YES
6320981	30423941	M.A.C.	CRediT	Investigation|Visualization|Supervision	Visualization	Analyzed the data	Visualization	YES
6320981	30423941	M.A.C.	CRediT	Investigation|Visualization|Supervision	Supervision	-	Supervision	YES
6320981	30423941	P.P.	CRediT	Methodology|Investigation|Supervision|Funding acquisition	Methodology	Performed the experiments	Methodology	YES
6320981	30423941	P.P.	CRediT	Methodology|Investigation|Supervision|Funding acquisition	Investigation	Performed the experiments	Investigation	YES
6320981	30423941	P.P.	CRediT	Methodology|Investigation|Supervision|Funding acquisition	Supervision	-	Supervision	YES
6320981	30423941	P.P.	CRediT	Methodology|Investigation|Supervision|Funding acquisition	Funding acquisition	-	Funding acquisition	YES
6320981	30423941	S.P.	CRediT	Investigation|Writing--review & editing|Supervision	Investigation	Performed the experiments	Investigation	YES
6320981	30423941	S.P.	CRediT	Investigation|Writing--review & editing|Supervision	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6320981	30423941	S.P.	CRediT	Investigation|Writing--review & editing|Supervision	Supervision	-	Supervision	YES
5750538	29156638	A. They	2	also contributed to manuscript writing and editing	also contributed to manuscript writing and editing	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5750538	29156638	A.A.N.	2	conceived and designed the study|prepared the initial draft of the disease literature	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5750538	29156638	A.A.N.	2	conceived and designed the study|prepared the initial draft of the disease literature	prepared the initial draft of the disease literature	Wrote the paper	Writing - Original Draft	YES
5750538	29156638	All authors	2	served as members of the expert panel	served as members of the expert panel	-	-	NO
5750538	29156638	F.Z.	2	devised patient feedback strategy and contributed in discussion writing	devised patient feedback strategy and contributed in discussion writing	Conceived and designed the experiments|Wrote the paper	Conceptualization	YES
5750538	29156638	M.A.H.	2	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5750538	29156638	M.T.A.	2	contributed in translation process of literature and revision of manuscript	contributed in translation process of literature and revision of manuscript	Wrote the paper	Writing - Review & Editing	YES
5750538	29156638	S.B.S.	2	contributed in translation process of literature and revision of manuscript	contributed in translation process of literature and revision of manuscript	Wrote the paper	Writing - Review & Editing	YES
5750539	29292711	C.S.	2	drafted the first version of this paper	drafted the first version of this paper	Wrote the paper	Writing - Original Draft	YES
5750539	29292711	J.S.	2	assisted in revising and added significant content to it	assisted in revising and added significant content to it	-	-	NO
2762465	19785738	EIO	2	conceived of the study and participated in its design and coordination and the interpretation of data	conceived of the study and participated in its design and coordination and the interpretation of data	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology|Project administration	YES
2762465	19785738	JB	2	conceived of the study, participated in its design and coordination and supervised the hplc analysis	conceived of the study, participated in its design and coordination and supervised the hplc analysis	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology|Project administration|Supervision	YES
2762465	19785738	LJ	2	conceived of the study and participated in its design and coordination	conceived of the study and participated in its design and coordination	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
2762465	19785738	SW	2	participated in the design of the study	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
4982199	27516339	All authors	2	carefully read and approved the final manuscript	carefully read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4982199	27516339	HD	2	contributed to the ngs analysis and data processing	contributed to the ngs analysis and data processing	Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Formal analysis|Resources	YES
4982199	27516339	HM	2	conducted the pigment analyses	conducted the pigment analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4982199	27516339	KM	2	participated in the real time pcr analysis	participated in the real time pcr analysis	Performed the experiments	Investigation	YES
4982199	27516339	KS	2	designed the research and drafted the manuscript|mainly performed the experiments	designed the research and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4982199	27516339	KS	2	designed the research and drafted the manuscript|mainly performed the experiments	mainly performed the experiments	Performed the experiments	Investigation	YES
4982199	27516339	MY	2	designed the research and drafted the manuscript|maintained the lilies and performed the segregation analysis	designed the research and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4982199	27516339	MY	2	designed the research and drafted the manuscript|maintained the lilies and performed the segregation analysis	maintained the lilies and performed the segregation analysis	Performed the experiments	Investigation	YES
4982199	27516339	TN	2	contributed to the ngs analysis and data processing|conducted the pigment analyses	contributed to the ngs analysis and data processing	Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Formal analysis|Resources	YES
4982199	27516339	TN	2	contributed to the ngs analysis and data processing|conducted the pigment analyses	conducted the pigment analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4982199	27516339	TS	2	contributed to the ngs analysis and data processing	contributed to the ngs analysis and data processing	Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Formal analysis|Resources	YES
6320991	30453596	D.D.	CRediT	Conceptualization|formal analysis|investigation|writing--original draft preparation|visualization	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6320991	30453596	D.D.	CRediT	Conceptualization|formal analysis|investigation|writing--original draft preparation|visualization	formal analysis	Analyzed the data	Formal analysis	YES
6320991	30453596	D.D.	CRediT	Conceptualization|formal analysis|investigation|writing--original draft preparation|visualization	investigation	Performed the experiments	Investigation	YES
6320991	30453596	D.D.	CRediT	Conceptualization|formal analysis|investigation|writing--original draft preparation|visualization	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6320991	30453596	D.D.	CRediT	Conceptualization|formal analysis|investigation|writing--original draft preparation|visualization	visualization	Analyzed the data	Visualization	YES
6320991	30453596	J.M.R.	CRediT	Conceptualization|resources|writing--original draft preparation|funding acquisition	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6320991	30453596	J.M.R.	CRediT	Conceptualization|resources|writing--original draft preparation|funding acquisition	resources	Contributed reagents/materials/analysis tools	Resources	YES
6320991	30453596	J.M.R.	CRediT	Conceptualization|resources|writing--original draft preparation|funding acquisition	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6320991	30453596	J.M.R.	CRediT	Conceptualization|resources|writing--original draft preparation|funding acquisition	funding acquisition	-	Funding acquisition	YES
6320991	30453596	J.Z.	CRediT	writing--review and editing|supervision|project administration	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6320991	30453596	J.Z.	CRediT	writing--review and editing|supervision|project administration	supervision	-	Supervision	YES
6320991	30453596	J.Z.	CRediT	writing--review and editing|supervision|project administration	project administration	-	Project administration	YES
6320991	30453596	M.A.	CRediT	Conceptualization|methodology|data curation|writing--original draft preparation|visualization|project administration	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6320991	30453596	M.A.	CRediT	Conceptualization|methodology|data curation|writing--original draft preparation|visualization|project administration	methodology	Performed the experiments	Methodology	YES
6320991	30453596	M.A.	CRediT	Conceptualization|methodology|data curation|writing--original draft preparation|visualization|project administration	data curation	Analyzed the data	Data curation	YES
6320991	30453596	M.A.	CRediT	Conceptualization|methodology|data curation|writing--original draft preparation|visualization|project administration	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6320991	30453596	M.A.	CRediT	Conceptualization|methodology|data curation|writing--original draft preparation|visualization|project administration	visualization	Analyzed the data	Visualization	YES
6320991	30453596	M.A.	CRediT	Conceptualization|methodology|data curation|writing--original draft preparation|visualization|project administration	project administration	-	Project administration	YES
6320991	30453596	M.N.	CRediT	Conceptualization|resources|funding acquisition	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6320991	30453596	M.N.	CRediT	Conceptualization|resources|funding acquisition	resources	Contributed reagents/materials/analysis tools	Resources	YES
6320991	30453596	M.N.	CRediT	Conceptualization|resources|funding acquisition	funding acquisition	-	Funding acquisition	YES
6320991	30453596	M.T.	CRediT	methodology|validation|formal analysis|investigation|writing--review and editing|writing--review and editing|project administration	methodology	Performed the experiments	Methodology	YES
6320991	30453596	M.T.	CRediT	methodology|validation|formal analysis|investigation|writing--review and editing|writing--review and editing|project administration	validation	Performed the experiments	Validation	YES
6320991	30453596	M.T.	CRediT	methodology|validation|formal analysis|investigation|writing--review and editing|writing--review and editing|project administration	formal analysis	Analyzed the data	Formal analysis	YES
6320991	30453596	M.T.	CRediT	methodology|validation|formal analysis|investigation|writing--review and editing|writing--review and editing|project administration	investigation	Performed the experiments	Investigation	YES
6320991	30453596	M.T.	CRediT	methodology|validation|formal analysis|investigation|writing--review and editing|writing--review and editing|project administration	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6320991	30453596	M.T.	CRediT	methodology|validation|formal analysis|investigation|writing--review and editing|writing--review and editing|project administration	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6320991	30453596	M.T.	CRediT	methodology|validation|formal analysis|investigation|writing--review and editing|writing--review and editing|project administration	project administration	-	Project administration	YES
6320991	30453596	N.P.	CRediT	formal analysis|investigation|writing--review and editing|visualization	formal analysis	Analyzed the data	Formal analysis	YES
6320991	30453596	N.P.	CRediT	formal analysis|investigation|writing--review and editing|visualization	investigation	Performed the experiments	Investigation	YES
6320991	30453596	N.P.	CRediT	formal analysis|investigation|writing--review and editing|visualization	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6320991	30453596	N.P.	CRediT	formal analysis|investigation|writing--review and editing|visualization	visualization	Analyzed the data	Visualization	YES
6320991	30453596	T.N.	CRediT	Conceptualization|writing--review and editing|supervision|project administration	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6320991	30453596	T.N.	CRediT	Conceptualization|writing--review and editing|supervision|project administration	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6320991	30453596	T.N.	CRediT	Conceptualization|writing--review and editing|supervision|project administration	supervision	-	Supervision	YES
6320991	30453596	T.N.	CRediT	Conceptualization|writing--review and editing|supervision|project administration	project administration	-	Project administration	YES
5418343	28529515	CA	2	performed measurements, data collection and statistical analysis, and wrote the manuscript	performed measurements, data collection and statistical analysis, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5418343	28529515	GA	2	provided scientific oversight in experimental design and interpretations and contributed in writing the manuscript	provided scientific oversight in experimental design and interpretations and contributed in writing the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Supervision|Writing - Original Draft	YES
5418343	28529515	MG	2	performed plant cultivation	performed plant cultivation	Performed the experiments	Investigation	YES
5418343	28529515	RP	2	performed plant cultivation|performed measurements, data collection and statistical analysis, and wrote the manuscript	performed plant cultivation	Performed the experiments	Investigation	YES
5418343	28529515	RP	2	performed plant cultivation|performed measurements, data collection and statistical analysis, and wrote the manuscript	performed measurements, data collection and statistical analysis, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5418343	28529515	SDP	2	provided scientific oversight in experimental design and interpretations and contributed in writing the manuscript|obtained funding for the study	provided scientific oversight in experimental design and interpretations and contributed in writing the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Supervision|Writing - Original Draft	YES
5418343	28529515	SDP	2	provided scientific oversight in experimental design and interpretations and contributed in writing the manuscript|obtained funding for the study	obtained funding for the study	-	Funding acquisition	YES
5418343	28529515	VDM	2	performed measurements, data collection and statistical analysis, and wrote the manuscript	performed measurements, data collection and statistical analysis, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5750540	29292713	Anoop K. Brar	2	made substantial contributions to literature reviews, interpretation of data, and drafting and critical revisions of the article	made substantial contributions to literature reviews, interpretation of data, and drafting and critical revisions of the article	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5750540	29292713	Connor R. Mullen	2	made substantial contributions to literature reviews, interpretation of data, and drafting and critical revisions of the article	made substantial contributions to literature reviews, interpretation of data, and drafting and critical revisions of the article	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5750540	29292713	Daniel J. Perry	2	made substantial contributions to literature reviews, interpretation of data, and drafting and critical revisions of the article	made substantial contributions to literature reviews, interpretation of data, and drafting and critical revisions of the article	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5750540	29292713	Horacio G. Carvajal	2	made substantial contributions to literature reviews, interpretation of data, and drafting and critical revisions of the article	made substantial contributions to literature reviews, interpretation of data, and drafting and critical revisions of the article	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5750540	29292713	Pirooz Eghtesady	2	was the key person responsible for the concept of the paper, interpretation of data and in the critical revision of drafts, as well as approval and submission of the manuscript	was the key person responsible for the concept of the paper, interpretation of data and in the critical revision of drafts, as well as approval and submission of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
4385608	25874227	Joel P. Arrais	2	contributed equally to the work presented here	contributed equally to the work presented here	-	-	NO
4385608	25874227	Jose Luis Oliveira	2	contributed equally to the work presented here	contributed equally to the work presented here	-	-	NO
2765950	19807926	BJW	2	was involved in placebo preparation, data collection and analyses, and in drafting of manuscript	was involved in placebo preparation, data collection and analyses, and in drafting of manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
2765950	19807926	CXS	2	was involved in analytical method development and data collection	was involved in analytical method development and data collection	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
2765950	19807926	GA	2	was responsible for irb preparation and research organization	was responsible for irb preparation and research organization	-	-	NO
2765950	19807926	MYW	2	generated study design, collected data, performed data analysis, and drafted manuscript	generated study design, collected data, performed data analysis, and drafted manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
2765950	19807926	VWH	2	was the clinical coordinator, conducted patient interviews, and setup database used to collect and organize data	was the clinical coordinator, conducted patient interviews, and setup database used to collect and organize data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Project administration|Software	YES
4396854	25875167	AJS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4396854	25875167	AJS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4396854	25875167	AJS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4396854	25875167	AJS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4396854	25875167	HSP	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4396854	25875167	HSP	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4396854	25875167	HSP	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4396854	25875167	JGO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4396854	25875167	JGO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4396854	25875167	JGO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4396854	25875167	JGO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4396854	25875167	JGO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4396854	25875167	LM	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4396854	25875167	LM	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4396854	25875167	PAB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4396854	25875167	PAB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4396854	25875167	PAB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4396854	25875167	PNG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4396854	25875167	PNG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4396854	25875167	PNG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4396854	25875167	RKO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4396854	25875167	RKO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4396854	25875167	RKO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4396854	25875167	RKO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4396854	25875167	RKO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2772850	19852781	ASIDL	2	led in the tool creation and scripting	led in the tool creation and scripting	-	-	NO
2772850	19852781	Second Life	2	to work collaboratively and together have created many of the chemistry related items in second life mentioned in this article	to work collaboratively and together have created many of the chemistry related items in second life mentioned in this article	-	-	NO
4982202	27514934	CG	2	performed experiments and tended the plants	performed experiments and tended the plants	Performed the experiments	Investigation	YES
4982202	27514934	CL	2	performed experiments and tended the plants	performed experiments and tended the plants	Performed the experiments	Investigation	YES
4982202	27514934	CZ	2	performed experiments and tended the plants	performed experiments and tended the plants	Performed the experiments	Investigation	YES
4982202	27514934	HX	2	performed experiments and tended the plants	performed experiments and tended the plants	Performed the experiments	Investigation	YES
4982202	27514934	LH	2	performed experiments and tended the plants	performed experiments and tended the plants	Performed the experiments	Investigation	YES
4982202	27514934	PW	2	performed experiments and tended the plants	performed experiments and tended the plants	Performed the experiments	Investigation	YES
4982202	27514934	SZ	2	designed the study, wrote part of the manuscript, and finalized the figures and tables	designed the study, wrote part of the manuscript, and finalized the figures and tables	Conceived and designed the experiments|Wrote the paper	Methodology|Visualization|Writing - Original Draft	YES
4982202	27514934	XW	2	designed the study, wrote part of the manuscript, and finalized the figures and tables	designed the study, wrote part of the manuscript, and finalized the figures and tables	Conceived and designed the experiments|Wrote the paper	Methodology|Visualization|Writing - Original Draft	YES
4982202	27514934	YZ	2	carried out most of the experiments and data analysis and wrote part of the manuscript	carried out most of the experiments and data analysis and wrote part of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6320993	30347860	A.H.S.	CRediT	Data curation|Investigation|Writing--review and editing	Data curation	Analyzed the data	Data curation	YES
6320993	30347860	A.H.S.	CRediT	Data curation|Investigation|Writing--review and editing	Investigation	Performed the experiments	Investigation	YES
6320993	30347860	A.H.S.	CRediT	Data curation|Investigation|Writing--review and editing	Writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6320993	30347860	A.L.	CRediT	Conceptualization|Funding acquisition|Project administration|Resources|Supervision|Writing--review and editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6320993	30347860	A.L.	CRediT	Conceptualization|Funding acquisition|Project administration|Resources|Supervision|Writing--review and editing	Funding acquisition	-	Funding acquisition	YES
6320993	30347860	A.L.	CRediT	Conceptualization|Funding acquisition|Project administration|Resources|Supervision|Writing--review and editing	Project administration	-	Project administration	YES
6320993	30347860	A.L.	CRediT	Conceptualization|Funding acquisition|Project administration|Resources|Supervision|Writing--review and editing	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6320993	30347860	A.L.	CRediT	Conceptualization|Funding acquisition|Project administration|Resources|Supervision|Writing--review and editing	Supervision	-	Supervision	YES
6320993	30347860	A.L.	CRediT	Conceptualization|Funding acquisition|Project administration|Resources|Supervision|Writing--review and editing	Writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6320993	30347860	A.T.	CRediT	Resources|Writing--review and editing	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6320993	30347860	A.T.	CRediT	Resources|Writing--review and editing	Writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6320993	30347860	F.C.	CRediT	Resources	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6320993	30347860	H.S.A.	CRediT	Conceptualization|Data curation|Formal analysis|Investigation|Methodology|Project administration|Validation|Writing--original draft|Writing--review and editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6320993	30347860	H.S.A.	CRediT	Conceptualization|Data curation|Formal analysis|Investigation|Methodology|Project administration|Validation|Writing--original draft|Writing--review and editing	Data curation	Analyzed the data	Data curation	YES
6320993	30347860	H.S.A.	CRediT	Conceptualization|Data curation|Formal analysis|Investigation|Methodology|Project administration|Validation|Writing--original draft|Writing--review and editing	Formal analysis	Analyzed the data	Formal analysis	YES
6320993	30347860	H.S.A.	CRediT	Conceptualization|Data curation|Formal analysis|Investigation|Methodology|Project administration|Validation|Writing--original draft|Writing--review and editing	Investigation	Performed the experiments	Investigation	YES
6320993	30347860	H.S.A.	CRediT	Conceptualization|Data curation|Formal analysis|Investigation|Methodology|Project administration|Validation|Writing--original draft|Writing--review and editing	Methodology	Performed the experiments	Methodology	YES
6320993	30347860	H.S.A.	CRediT	Conceptualization|Data curation|Formal analysis|Investigation|Methodology|Project administration|Validation|Writing--original draft|Writing--review and editing	Project administration	-	Project administration	YES
6320993	30347860	H.S.A.	CRediT	Conceptualization|Data curation|Formal analysis|Investigation|Methodology|Project administration|Validation|Writing--original draft|Writing--review and editing	Validation	Performed the experiments	Validation	YES
6320993	30347860	H.S.A.	CRediT	Conceptualization|Data curation|Formal analysis|Investigation|Methodology|Project administration|Validation|Writing--original draft|Writing--review and editing	Writing--original draft	Wrote the paper	Writing - Original Draft	YES
6320993	30347860	H.S.A.	CRediT	Conceptualization|Data curation|Formal analysis|Investigation|Methodology|Project administration|Validation|Writing--original draft|Writing--review and editing	Writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6320993	30347860	K.K.	CRediT	Resources|Writing--review and editing	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6320993	30347860	K.K.	CRediT	Resources|Writing--review and editing	Writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6320993	30347860	M.R.V.	CRediT	Resources	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6320993	30347860	R.S.	CRediT	Resources	Resources	Contributed reagents/materials/analysis tools	Resources	YES
5750542	29186880	Kazuhiro P. Izawa	2	designed the study, collected, analyzed, and interpreted the data, and secured funding for the study	designed the study, collected, analyzed, and interpreted the data, and secured funding for the study	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Funding acquisition|Investigation|Methodology	YES
5750542	29186880	Koji Hiraki	2	helped to draft and critically revise the manuscript for important intellectual content	helped to draft and critically revise the manuscript for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5750542	29186880	Satoshi Watanabe	2	helped to draft and critically revise the manuscript for important intellectual content	helped to draft and critically revise the manuscript for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5750542	29186880	Yasuyuki Hirano	2	helped to draft and critically revise the manuscript for important intellectual content	helped to draft and critically revise the manuscript for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5750542	29186880	Yusuke Kasahara	2	helped to draft and critically revise the manuscript for important intellectual content	helped to draft and critically revise the manuscript for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4396855	25875824	CCC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4396855	25875824	CCW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4396855	25875824	CCW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4396855	25875824	CCW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4396855	25875824	CFS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4396855	25875824	CHH	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4396855	25875824	GCC	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4396855	25875824	HYC	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4396855	25875824	JJWC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4396855	25875824	JJWC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4396855	25875824	JJWC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4396855	25875824	KYS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4396855	25875824	QSH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4396855	25875824	SLY	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4396855	25875824	SLY	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4396855	25875824	SLY	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4396855	25875824	SYC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5418346	28529514	CY	PLoS52	performed the experiments|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5418346	28529514	CY	PLoS52	performed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5418346	28529514	DZ	PLoS52	revised and approved the manuscript	revised and approved the manuscript	Wrote the paper	Writing - Review & Editing	YES
5418346	28529514	GDL	PLoS52	revised and approved the manuscript	revised and approved the manuscript	Wrote the paper	Writing - Review & Editing	YES
5418346	28529514	GPL	PLoS52	conceived and designed the experiments|revised and approved the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5418346	28529514	GPL	PLoS52	conceived and designed the experiments|revised and approved the manuscript	revised and approved the manuscript	Wrote the paper	Writing - Review & Editing	YES
5418346	28529514	HZ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5418346	28529514	JZ	PLoS52	conceived and designed the experiments|revised and approved the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5418346	28529514	JZ	PLoS52	conceived and designed the experiments|revised and approved the manuscript	revised and approved the manuscript	Wrote the paper	Writing - Review & Editing	YES
5418346	28529514	XC	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5418346	28529514	XD	PLoS52	performed the experiments|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5418346	28529514	XD	PLoS52	performed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5418346	28529514	XFC	PLoS52	performed the experiments|revised and approved the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5418346	28529514	XFC	PLoS52	performed the experiments|revised and approved the manuscript	revised and approved the manuscript	Wrote the paper	Writing - Review & Editing	YES
5418346	28529514	XL	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5418346	28529514	YA	PLoS52	revised and approved the manuscript	revised and approved the manuscript	Wrote the paper	Writing - Review & Editing	YES
5418346	28529514	ZW	PLoS52	revised and approved the manuscript	revised and approved the manuscript	Wrote the paper	Writing - Review & Editing	YES
2777900	19900275	MG	2	performed the nmr experiments and data analysis|conceived of the dft studies and implemented them|contributed equally to this manuscript	performed the nmr experiments and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
2777900	19900275	MG	2	performed the nmr experiments and data analysis|conceived of the dft studies and implemented them|contributed equally to this manuscript	conceived of the dft studies and implemented them	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
2777900	19900275	MG	2	performed the nmr experiments and data analysis|conceived of the dft studies and implemented them|contributed equally to this manuscript	contributed equally to this manuscript	-	-	NO
2777900	19900275	NP	2	conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
2777900	19900275	PKM	2	conceived the study|drafted the manuscript, and all authors read and approved the final manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
2777900	19900275	PKM	2	conceived the study|drafted the manuscript, and all authors read and approved the final manuscript	drafted the manuscript, and all authors read and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
2777900	19900275	PKN	2	prepared the samples and carried out all the non-nmr experiments|conceived of the dft studies and implemented them|contributed equally to this manuscript	prepared the samples and carried out all the non-nmr experiments	Performed the experiments	Investigation	YES
2777900	19900275	PKN	2	prepared the samples and carried out all the non-nmr experiments|conceived of the dft studies and implemented them|contributed equally to this manuscript	conceived of the dft studies and implemented them	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
2777900	19900275	PKN	2	prepared the samples and carried out all the non-nmr experiments|conceived of the dft studies and implemented them|contributed equally to this manuscript	contributed equally to this manuscript	-	-	NO
4982206	27519738	All authors	2	contributed extensively to the work presented in this paper	contributed extensively to the work presented in this paper	-	-	NO
4982206	27519738	IM	2	designed and performed experiments and wrote the manuscript	designed and performed experiments and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
4982206	27519738	MP	2	designed and performed experiments and wrote the manuscript	designed and performed experiments and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
4982206	27519738	TS	2	supervised the work, helped in evaluation and interpretation of data and edited the manuscript	supervised the work, helped in evaluation and interpretation of data and edited the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Supervision|Writing - Review & Editing	YES
4396977	25875676	JAD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4396977	25875676	JAD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4396977	25875676	JAD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4396977	25875676	JAD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4396977	25875676	LDB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4396977	25875676	LDB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4396977	25875676	LDB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4396977	25875676	LDB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6321000	30249025	A.B.	PLoS52	contributed to the data analysis|wrote the paper	contributed to the data analysis	Analyzed the data	Formal analysis	YES
6321000	30249025	A.B.	PLoS52	contributed to the data analysis|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6321000	30249025	GSK	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
6321000	30249025	J.A.	PLoS52	contributed to the data analysis	contributed to the data analysis	Analyzed the data	Formal analysis	YES
6321000	30249025	M.B.	PLoS52	contributed to the data analysis	contributed to the data analysis	Analyzed the data	Formal analysis	YES
6321000	30249025	M.O.	PLoS52	contributed to the data analysis|wrote the paper	contributed to the data analysis	Analyzed the data	Formal analysis	YES
6321000	30249025	M.O.	PLoS52	contributed to the data analysis|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6321000	30249025	W.S.	PLoS52	conceived and designed the experiments|contributed to the data analysis|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6321000	30249025	W.S.	PLoS52	conceived and designed the experiments|contributed to the data analysis|wrote the paper	contributed to the data analysis	Analyzed the data	Formal analysis	YES
6321000	30249025	W.S.	PLoS52	conceived and designed the experiments|contributed to the data analysis|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
2788561	19930546	AL	2	were involved in the interpretation of the results and reviewed the manuscript	were involved in the interpretation of the results and reviewed the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
2788561	19930546	All authors	2	contributed to execution of the presented work	contributed to execution of the presented work	Performed the experiments	Investigation	YES
2788561	19930546	ES	2	designed the study, acquired and interpreted the data and drafted the manuscript	designed the study, acquired and interpreted the data and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
2788561	19930546	GD	2	was involved in the interpreration of the results and drafted the manuscript	was involved in the interpreration of the results and drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
2788561	19930546	HW	2	designed the study, interpreted data and drafted the manuscript	designed the study, interpreted data and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
2788561	19930546	MS	2	were involved in the interpretation of the results and reviewed the manuscript	were involved in the interpretation of the results and reviewed the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
2788561	19930546	NRJ	2	aquired and interpreted data	aquired and interpreted data	Analyzed the data	Formal analysis	YES
2788561	19930546	UV	2	were involved in the interpretation of the results and reviewed the manuscript	were involved in the interpretation of the results and reviewed the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
2788561	19930546	WK	2	was involved in the acquisition of data, interpretation of the results and reviewed the manuscript	was involved in the acquisition of data, interpretation of the results and reviewed the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
5418354	28529516	AM-P	2	carried out experimental work and data analysis	carried out experimental work and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5418354	28529516	CR	2	conceived the idea and contributed to the experimental design, data analysis, interpretation of results and writing manuscript	conceived the idea and contributed to the experimental design, data analysis, interpretation of results and writing manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
5418354	28529516	EL-S	2	conceived the idea and contributed to the experimental design, data analysis, interpretation of results and writing manuscript	conceived the idea and contributed to the experimental design, data analysis, interpretation of results and writing manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
5418354	28529516	MC-O	2	carried out experimental design, experimental work, data analysis, and writing of the manuscript	carried out experimental design, experimental work, data analysis, and writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4982211	27515514	GP	2	designed the study and prepared the manuscript	designed the study and prepared the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4982211	27515514	JL	2	designed the study and prepared the manuscript|performed computational analyses	designed the study and prepared the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4982211	27515514	JL	2	designed the study and prepared the manuscript|performed computational analyses	performed computational analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4982211	27515514	YN	2	designed the study and prepared the manuscript|performed computational analyses|developed and designed the web server	designed the study and prepared the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4982211	27515514	YN	2	designed the study and prepared the manuscript|performed computational analyses|developed and designed the web server	performed computational analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4982211	27515514	YN	2	designed the study and prepared the manuscript|performed computational analyses|developed and designed the web server	developed and designed the web server	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
4396978	25875111	BO	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4396978	25875111	BO	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4396978	25875111	BO	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4396978	25875111	CD	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4396978	25875111	CD	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4396978	25875111	CD	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4396978	25875111	DL	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4396978	25875111	DL	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4396978	25875111	EL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4396978	25875111	EL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4396978	25875111	EL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4396978	25875111	GB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4396978	25875111	GB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4396978	25875111	GB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4396978	25875111	KM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4396978	25875111	KM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4396978	25875111	KM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4396978	25875111	NW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4396978	25875111	NW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4396978	25875111	NW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4396978	25875111	NW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2829562	20181001	TO	2	planned and participated in all aspects of the work	planned and participated in all aspects of the work	Conceived and designed the experiments	Conceptualization	YES
6321008	30257528	A.U.	CRediT	Conceptualization|Methodology|Writing-original draft preparation	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6321008	30257528	A.U.	CRediT	Conceptualization|Methodology|Writing-original draft preparation	Methodology	Performed the experiments	Methodology	YES
6321008	30257528	A.U.	CRediT	Conceptualization|Methodology|Writing-original draft preparation	Writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
6321008	30257528	C.-A.I.	CRediT	Conceptualization|Writing-review & editing|Supervision	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6321008	30257528	C.-A.I.	CRediT	Conceptualization|Writing-review & editing|Supervision	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6321008	30257528	C.-A.I.	CRediT	Conceptualization|Writing-review & editing|Supervision	Supervision	-	Supervision	YES
6321008	30257528	L.M.R.	CRediT	Writing-review & editing	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6321008	30257528	M.I.	CRediT	Writing-review & editing	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6321008	30257528	R.N.	CRediT	Writing-review & editing	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6321008	30257528	S.C.H.	CRediT	Conceptualization|Writing-original draft preparation|Writing-review & editing|Supervision	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6321008	30257528	S.C.H.	CRediT	Conceptualization|Writing-original draft preparation|Writing-review & editing|Supervision	Writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
6321008	30257528	S.C.H.	CRediT	Conceptualization|Writing-original draft preparation|Writing-review & editing|Supervision	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6321008	30257528	S.C.H.	CRediT	Conceptualization|Writing-original draft preparation|Writing-review & editing|Supervision	Supervision	-	Supervision	YES
5418358	28529517	LG	2	contributed in the tables	contributed in the tables	-	-	NO
5418358	28529517	MW	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5418358	28529517	QS	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5418358	28529517	SD	2	contributed in the figures	contributed in the figures	-	Visualization	YES
5418358	28529517	SG	2	wrote the manuscript|revised the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5418358	28529517	SG	2	wrote the manuscript|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5418358	28529517	YS	2	contributed in the figures	contributed in the figures	-	Visualization	YES
5750544	29292714	F.A.	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5750544	29292714	F.V.	PLoS52	conceived, designed and performed the experiments, they also analyzed the data	conceived, designed and performed the experiments, they also analyzed the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation|Methodology	YES
5750544	29292714	J.S.	PLoS52	conceived, designed and performed the experiments, they also analyzed the data	conceived, designed and performed the experiments, they also analyzed the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation|Methodology	YES
5750544	29292714	L.R.P.	PLoS52	conceived, designed and performed the experiments, they also analyzed the data|wrote the paper	conceived, designed and performed the experiments, they also analyzed the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation|Methodology	YES
5750544	29292714	L.R.P.	PLoS52	conceived, designed and performed the experiments, they also analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5750544	29292714	M.A.A.P.	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5750544	29292714	M.G.B.	PLoS52	conceived, designed and performed the experiments, they also analyzed the data	conceived, designed and performed the experiments, they also analyzed the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation|Methodology	YES
5750544	29292714	R.L.	PLoS52	conceived, designed and performed the experiments, they also analyzed the data	conceived, designed and performed the experiments, they also analyzed the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation|Methodology	YES
4396979	25876035	AB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4396979	25876035	AB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4396979	25876035	AB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4396979	25876035	AP	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4396979	25876035	AP	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4396979	25876035	EC	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4396979	25876035	EC	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4396979	25876035	EC	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4396979	25876035	EC	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4396979	25876035	PJW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4396979	25876035	PJW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4396979	25876035	PJW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4396979	25876035	SV	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4396979	25876035	SV	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4396979	25876035	SV	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4982217	27515389	AL	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
4982217	27515389	AS	PLoS52	designed the study|analyzed the data|drafted the paper	designed the study	Conceived and designed the experiments	Methodology	YES
4982217	27515389	AS	PLoS52	designed the study|analyzed the data|drafted the paper	analyzed the data	Analyzed the data	Formal analysis	YES
4982217	27515389	AS	PLoS52	designed the study|analyzed the data|drafted the paper	drafted the paper	Wrote the paper	Writing - Original Draft	YES
4982217	27515389	AZ	PLoS52	designed the study|drafted the paper	designed the study	Conceived and designed the experiments	Methodology	YES
4982217	27515389	AZ	PLoS52	designed the study|drafted the paper	drafted the paper	Wrote the paper	Writing - Original Draft	YES
4982217	27515389	All authors	PLoS52	critically reviewed the paper	critically reviewed the paper	Wrote the paper	Writing - Review & Editing	YES
4982217	27515389	HDZ	PLoS52	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
4982217	27515389	PSK	PLoS52	designed the study|drafted the paper	designed the study	Conceived and designed the experiments	Methodology	YES
4982217	27515389	PSK	PLoS52	designed the study|drafted the paper	drafted the paper	Wrote the paper	Writing - Original Draft	YES
4982217	27515389	TKR	PLoS52	analyzed the data|drafted the paper	analyzed the data	Analyzed the data	Formal analysis	YES
4982217	27515389	TKR	PLoS52	analyzed the data|drafted the paper	drafted the paper	Wrote the paper	Writing - Original Draft	YES
6321009	30428623	B.L.	CRediT	Data curation	Data curation	Analyzed the data	Data curation	YES
6321009	30428623	R.F.	CRediT	Data curation|Formal analysis|Methodology|Writing--original draft	Data curation	Analyzed the data	Data curation	YES
6321009	30428623	R.F.	CRediT	Data curation|Formal analysis|Methodology|Writing--original draft	Formal analysis	Analyzed the data	Formal analysis	YES
6321009	30428623	R.F.	CRediT	Data curation|Formal analysis|Methodology|Writing--original draft	Methodology	Performed the experiments	Methodology	YES
6321009	30428623	R.F.	CRediT	Data curation|Formal analysis|Methodology|Writing--original draft	Writing--original draft	Wrote the paper	Writing - Original Draft	YES
6321009	30428623	X.L.	CRediT	Data curation|Formal analysis|Visualization|Writing--review & editing	Data curation	Analyzed the data	Data curation	YES
6321009	30428623	X.L.	CRediT	Data curation|Formal analysis|Visualization|Writing--review & editing	Formal analysis	Analyzed the data	Formal analysis	YES
6321009	30428623	X.L.	CRediT	Data curation|Formal analysis|Visualization|Writing--review & editing	Visualization	Analyzed the data	Visualization	YES
6321009	30428623	X.L.	CRediT	Data curation|Formal analysis|Visualization|Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6321009	30428623	Y.L.	CRediT	Project administration|Supervision	Project administration	-	Project administration	YES
6321009	30428623	Y.L.	CRediT	Project administration|Supervision	Supervision	-	Supervision	YES
4385615	25874233	Diana Marquez-Garban	2	contributed equally to this work	contributed equally to this work	-	-	NO
4385615	25874233	Nalo Hamilton	2	contributed equally to this work	contributed equally to this work	-	-	NO
2833158	20181222	AW	2	participated in xafs data measurements and analysis, and drafted the manuscript	participated in xafs data measurements and analysis, and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
2833158	20181222	CH	2	participated in design and coordination of the study, sample preparation, and n2 adsorption analysis	participated in design and coordination of the study, sample preparation, and n2 adsorption analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology|Project administration	YES
2833158	20181222	RH	2	performed the sample preparation and n2 adsorption analysis	performed the sample preparation and n2 adsorption analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
2833158	20181222	TR	2	participated in xafs data measurements and analysis, and design and coordination of the study	participated in xafs data measurements and analysis, and design and coordination of the study	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology|Project administration	YES
5418363	28529519	HB	2	participated in revising the manuscript	participated in revising the manuscript	Wrote the paper	Writing - Review & Editing	YES
5418363	28529519	JF	2	designed the experiments|helped draft and revise the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5418363	28529519	JF	2	designed the experiments|helped draft and revise the manuscript	helped draft and revise the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5418363	28529519	JW	2	designed the experiments|performed the experiments, analyzed the data, and drafted the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5418363	28529519	JW	2	designed the experiments|performed the experiments, analyzed the data, and drafted the manuscript	performed the experiments, analyzed the data, and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5418363	28529519	PF	2	participated in revising the manuscript	participated in revising the manuscript	Wrote the paper	Writing - Review & Editing	YES
5418363	28529519	SL	2	initiated the research	initiated the research	Conceived and designed the experiments	Conceptualization	YES
5418363	28529519	WJ	2	contributed to plant material cultivation	contributed to plant material cultivation	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5418363	28529519	YL	2	initiated the research|designed the experiments|helped draft and revise the manuscript	initiated the research	Conceived and designed the experiments	Conceptualization	YES
5418363	28529519	YL	2	initiated the research|designed the experiments|helped draft and revise the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5418363	28529519	YL	2	initiated the research|designed the experiments|helped draft and revise the manuscript	helped draft and revise the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5750545	29232859	C.S.	2	performed the research|analyzed data	performed the research	Performed the experiments	Investigation	YES
5750545	29232859	C.S.	2	performed the research|analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5750545	29232859	D.K.	2	designed the research|performed the research|analyzed data|wrote the manuscript|initiated the project	designed the research	Conceived and designed the experiments	Methodology	YES
5750545	29232859	D.K.	2	designed the research|performed the research|analyzed data|wrote the manuscript|initiated the project	performed the research	Performed the experiments	Investigation	YES
5750545	29232859	D.K.	2	designed the research|performed the research|analyzed data|wrote the manuscript|initiated the project	analyzed data	Analyzed the data	Formal analysis	YES
5750545	29232859	D.K.	2	designed the research|performed the research|analyzed data|wrote the manuscript|initiated the project	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5750545	29232859	D.K.	2	designed the research|performed the research|analyzed data|wrote the manuscript|initiated the project	initiated the project	Conceived and designed the experiments	Conceptualization	YES
5750545	29232859	H.O.T.	2	designed the research|analyzed data|wrote the manuscript|initiated the project	designed the research	Conceived and designed the experiments	Methodology	YES
5750545	29232859	H.O.T.	2	designed the research|analyzed data|wrote the manuscript|initiated the project	analyzed data	Analyzed the data	Formal analysis	YES
5750545	29232859	H.O.T.	2	designed the research|analyzed data|wrote the manuscript|initiated the project	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5750545	29232859	H.O.T.	2	designed the research|analyzed data|wrote the manuscript|initiated the project	initiated the project	Conceived and designed the experiments	Conceptualization	YES
5750545	29232859	M.A.B.	2	performed the research|analyzed data	performed the research	Performed the experiments	Investigation	YES
5750545	29232859	M.A.B.	2	performed the research|analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
2848039	20214785	AAG	2	conceived of the study, participated in its design and coordination	conceived of the study, participated in its design and coordination	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
2848039	20214785	MK	2	has formulated the research idea and prepared the manuscript draft version	has formulated the research idea and prepared the manuscript draft version	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
2848039	20214785	RK	2	coordinated efforts of the chemdiv lead discovery team	coordinated efforts of the chemdiv lead discovery team	-	Project administration	YES
2848039	20214785	TOX	2	performed final data check	performed final data check	Performed the experiments	Investigation	YES
2848039	20214785	YL	2	performed final data check	performed final data check	Performed the experiments	Investigation	YES
4396980	25875471	AS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4396980	25875471	DG	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4396980	25875471	KC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4396980	25875471	KC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4396980	25875471	KC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4396980	25875471	ME	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4396980	25875471	MM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4396980	25875471	XL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4396980	25875471	XL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4396980	25875471	XL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4396980	25875471	XL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4982218	27516204	CW	PLoS52	performed experiments|analyzed results	performed experiments	Performed the experiments	Investigation	YES
4982218	27516204	CW	PLoS52	performed experiments|analyzed results	analyzed results	Analyzed the data	Formal analysis	YES
4982218	27516204	IL	PLoS52	designed experiments|performed experiments|analyzed results|wrote the paper	designed experiments	Conceived and designed the experiments	Methodology	YES
4982218	27516204	IL	PLoS52	designed experiments|performed experiments|analyzed results|wrote the paper	performed experiments	Performed the experiments	Investigation	YES
4982218	27516204	IL	PLoS52	designed experiments|performed experiments|analyzed results|wrote the paper	analyzed results	Analyzed the data	Formal analysis	YES
4982218	27516204	IL	PLoS52	designed experiments|performed experiments|analyzed results|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4982218	27516204	LF	PLoS52	designed experiments|performed experiments|analyzed results|wrote the paper	designed experiments	Conceived and designed the experiments	Methodology	YES
4982218	27516204	LF	PLoS52	designed experiments|performed experiments|analyzed results|wrote the paper	performed experiments	Performed the experiments	Investigation	YES
4982218	27516204	LF	PLoS52	designed experiments|performed experiments|analyzed results|wrote the paper	analyzed results	Analyzed the data	Formal analysis	YES
4982218	27516204	LF	PLoS52	designed experiments|performed experiments|analyzed results|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4982218	27516204	TS	PLoS52	designed experiments|wrote the paper	designed experiments	Conceived and designed the experiments	Methodology	YES
4982218	27516204	TS	PLoS52	designed experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4982218	27516204	all authors	PLoS52	edited and approved of the manuscript	edited and approved of the manuscript	Wrote the paper	Writing - Review & Editing	YES
6321021	30572636	A.J.	CRediT	software|investigation|writing--original draft preparation	software	Contributed reagents/materials/analysis tools	Software	YES
6321021	30572636	A.J.	CRediT	software|investigation|writing--original draft preparation	investigation	Performed the experiments	Investigation	YES
6321021	30572636	A.J.	CRediT	software|investigation|writing--original draft preparation	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6321021	30572636	A.R.B.	CRediT	resources	resources	Contributed reagents/materials/analysis tools	Resources	YES
6321021	30572636	A.S.F.	CRediT	resources	resources	Contributed reagents/materials/analysis tools	Resources	YES
6321021	30572636	J.G.C.	CRediT	Conceptualization|methodology|validation|formal analysis|investigation|resources|writing--original draft preparation|supervision	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6321021	30572636	J.G.C.	CRediT	Conceptualization|methodology|validation|formal analysis|investigation|resources|writing--original draft preparation|supervision	methodology	Performed the experiments	Methodology	YES
6321021	30572636	J.G.C.	CRediT	Conceptualization|methodology|validation|formal analysis|investigation|resources|writing--original draft preparation|supervision	validation	Performed the experiments	Validation	YES
6321021	30572636	J.G.C.	CRediT	Conceptualization|methodology|validation|formal analysis|investigation|resources|writing--original draft preparation|supervision	formal analysis	Analyzed the data	Formal analysis	YES
6321021	30572636	J.G.C.	CRediT	Conceptualization|methodology|validation|formal analysis|investigation|resources|writing--original draft preparation|supervision	investigation	Performed the experiments	Investigation	YES
6321021	30572636	J.G.C.	CRediT	Conceptualization|methodology|validation|formal analysis|investigation|resources|writing--original draft preparation|supervision	resources	Contributed reagents/materials/analysis tools	Resources	YES
6321021	30572636	J.G.C.	CRediT	Conceptualization|methodology|validation|formal analysis|investigation|resources|writing--original draft preparation|supervision	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6321021	30572636	J.G.C.	CRediT	Conceptualization|methodology|validation|formal analysis|investigation|resources|writing--original draft preparation|supervision	supervision	-	Supervision	YES
6321021	30572636	M.E.M.A.	CRediT	resources	resources	Contributed reagents/materials/analysis tools	Resources	YES
6321021	30572636	R.C.	CRediT	software|investigation|writing--original draft preparation	software	Contributed reagents/materials/analysis tools	Software	YES
6321021	30572636	R.C.	CRediT	software|investigation|writing--original draft preparation	investigation	Performed the experiments	Investigation	YES
6321021	30572636	R.C.	CRediT	software|investigation|writing--original draft preparation	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6321021	30572636	T.S.d.A.	CRediT	Conceptualization|methodology|validation|formal analysis|investigation|resources|writing--original draft preparation|supervision|project administration	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6321021	30572636	T.S.d.A.	CRediT	Conceptualization|methodology|validation|formal analysis|investigation|resources|writing--original draft preparation|supervision|project administration	methodology	Performed the experiments	Methodology	YES
6321021	30572636	T.S.d.A.	CRediT	Conceptualization|methodology|validation|formal analysis|investigation|resources|writing--original draft preparation|supervision|project administration	validation	Performed the experiments	Validation	YES
6321021	30572636	T.S.d.A.	CRediT	Conceptualization|methodology|validation|formal analysis|investigation|resources|writing--original draft preparation|supervision|project administration	formal analysis	Analyzed the data	Formal analysis	YES
6321021	30572636	T.S.d.A.	CRediT	Conceptualization|methodology|validation|formal analysis|investigation|resources|writing--original draft preparation|supervision|project administration	investigation	Performed the experiments	Investigation	YES
6321021	30572636	T.S.d.A.	CRediT	Conceptualization|methodology|validation|formal analysis|investigation|resources|writing--original draft preparation|supervision|project administration	resources	Contributed reagents/materials/analysis tools	Resources	YES
6321021	30572636	T.S.d.A.	CRediT	Conceptualization|methodology|validation|formal analysis|investigation|resources|writing--original draft preparation|supervision|project administration	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6321021	30572636	T.S.d.A.	CRediT	Conceptualization|methodology|validation|formal analysis|investigation|resources|writing--original draft preparation|supervision|project administration	supervision	-	Supervision	YES
6321021	30572636	T.S.d.A.	CRediT	Conceptualization|methodology|validation|formal analysis|investigation|resources|writing--original draft preparation|supervision|project administration	project administration	-	Project administration	YES
6321021	30572636	all authors	CRediT	writing--review & editing	writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
5420556	28533787	CZ	1	Manuscript draft|Analyzing data|Conception and supervision of the research	Manuscript draft	Wrote the paper	Writing - Original Draft	YES
5420556	28533787	CZ	1	Manuscript draft|Analyzing data|Conception and supervision of the research	Analyzing data	Analyzed the data	Formal analysis	YES
5420556	28533787	CZ	1	Manuscript draft|Analyzing data|Conception and supervision of the research	Conception and supervision of the research	Conceived and designed the experiments	Conceptualization|Supervision	YES
5420556	28533787	FC	1	Analyzing data	Analyzing data	Analyzed the data	Formal analysis	YES
5420556	28533787	HX	1	Experiment	Experiment	-	-	NO
5420556	28533787	JQ	1	Experiment	Experiment	-	-	NO
5420556	28533787	JW	1	Manuscript draft|Experiment	Manuscript draft	Wrote the paper	Writing - Original Draft	YES
5420556	28533787	JW	1	Manuscript draft|Experiment	Experiment	-	-	NO
5420556	28533787	LH	1	Experiment	Experiment	-	-	NO
5420556	28533787	QZ	1	Experiment	Experiment	-	-	NO
5420556	28533787	SZ	1	Experiment	Experiment	-	-	NO
5420556	28533787	TL	1	Experiment	Experiment	-	-	NO
5420556	28533787	XW	1	Manuscript draft|Conception and supervision of the research	Manuscript draft	Wrote the paper	Writing - Original Draft	YES
5420556	28533787	XW	1	Manuscript draft|Conception and supervision of the research	Conception and supervision of the research	Conceived and designed the experiments	Conceptualization|Supervision	YES
5420556	28533787	YZ	1	Experiment	Experiment	-	-	NO
2851693	20350297	AD	2	performed sample collection	performed sample collection	Performed the experiments	Investigation	YES
2851693	20350297	BT	2	participated in the separation and identification of the compounds and performed dpph tests	participated in the separation and identification of the compounds and performed dpph tests	Performed the experiments	Investigation	YES
2851693	20350297	HN	2	performed the antimicrobial tests	performed the antimicrobial tests	Performed the experiments	Investigation	YES
2851693	20350297	IT	2	performed performed the extractions and some of the chromatographic separations	performed performed the extractions and some of the chromatographic separations	Performed the experiments	Investigation	YES
2851693	20350297	MN	2	performed the antimicrobial tests	performed the antimicrobial tests	Performed the experiments	Investigation	YES
2851693	20350297	VB	2	conceived of the study, participated in its design and coordination and contributed to drafting the manuscript	conceived of the study, participated in its design and coordination and contributed to drafting the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
4396981	25874618	AQG	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4396981	25874618	AQG	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4396981	25874618	AQG	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4396981	25874618	MAD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4396981	25874618	MAD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4396981	25874618	MAD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4396981	25874618	MAD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4396981	25874618	RHPS	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4396981	25874618	RHPS	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6321022	30544604	A.N.	CRediT	formal analysis|investigation	formal analysis	Analyzed the data	Formal analysis	YES
6321022	30544604	A.N.	CRediT	formal analysis|investigation	investigation	Performed the experiments	Investigation	YES
6321022	30544604	C.E.S.-J.	CRediT	methodology|formal analysis|investigation|writing--original draft preparation	methodology	Performed the experiments	Methodology	YES
6321022	30544604	C.E.S.-J.	CRediT	methodology|formal analysis|investigation|writing--original draft preparation	formal analysis	Analyzed the data	Formal analysis	YES
6321022	30544604	C.E.S.-J.	CRediT	methodology|formal analysis|investigation|writing--original draft preparation	investigation	Performed the experiments	Investigation	YES
6321022	30544604	C.E.S.-J.	CRediT	methodology|formal analysis|investigation|writing--original draft preparation	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6321022	30544604	J.C.-D.	CRediT	Conceptualization|methodology|validation|writing--review and editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6321022	30544604	J.C.-D.	CRediT	Conceptualization|methodology|validation|writing--review and editing	methodology	Performed the experiments	Methodology	YES
6321022	30544604	J.C.-D.	CRediT	Conceptualization|methodology|validation|writing--review and editing	validation	Performed the experiments	Validation	YES
6321022	30544604	J.C.-D.	CRediT	Conceptualization|methodology|validation|writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6321022	30544604	J.C.D.	CRediT	writing--original draft preparation	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6321022	30544604	L.P.-L.	CRediT	Conceptualization|methodology|validation|writing--review and editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6321022	30544604	L.P.-L.	CRediT	Conceptualization|methodology|validation|writing--review and editing	methodology	Performed the experiments	Methodology	YES
6321022	30544604	L.P.-L.	CRediT	Conceptualization|methodology|validation|writing--review and editing	validation	Performed the experiments	Validation	YES
6321022	30544604	L.P.-L.	CRediT	Conceptualization|methodology|validation|writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6321022	30544604	M.A.M.-G.	CRediT	formal analysis|investigation	formal analysis	Analyzed the data	Formal analysis	YES
6321022	30544604	M.A.M.-G.	CRediT	formal analysis|investigation	investigation	Performed the experiments	Investigation	YES
6321022	30544604	M.M.-S.	CRediT	formal analysis|investigation	formal analysis	Analyzed the data	Formal analysis	YES
6321022	30544604	M.M.-S.	CRediT	formal analysis|investigation	investigation	Performed the experiments	Investigation	YES
6321022	30544604	M.S.	CRediT	methodology|formal analysis|investigation	methodology	Performed the experiments	Methodology	YES
6321022	30544604	M.S.	CRediT	methodology|formal analysis|investigation	formal analysis	Analyzed the data	Formal analysis	YES
6321022	30544604	M.S.	CRediT	methodology|formal analysis|investigation	investigation	Performed the experiments	Investigation	YES
6321022	30544604	P.B.	CRediT	supervision	supervision	-	Supervision	YES
6321022	30544604	S.G.	CRediT	methodology|validation|writing--review and editing	methodology	Performed the experiments	Methodology	YES
6321022	30544604	S.G.	CRediT	methodology|validation|writing--review and editing	validation	Performed the experiments	Validation	YES
6321022	30544604	S.G.	CRediT	methodology|validation|writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6321022	30544604	V.B.-Y.	CRediT	methodology|writing--review and editing|supervision	methodology	Performed the experiments	Methodology	YES
6321022	30544604	V.B.-Y.	CRediT	methodology|writing--review and editing|supervision	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6321022	30544604	V.B.-Y.	CRediT	methodology|writing--review and editing|supervision	supervision	-	Supervision	YES
6321022	30544604	V.M.	CRediT	methodology|writing--original draft preparation|writing--review and editing|supervision	methodology	Performed the experiments	Methodology	YES
6321022	30544604	V.M.	CRediT	methodology|writing--original draft preparation|writing--review and editing|supervision	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6321022	30544604	V.M.	CRediT	methodology|writing--original draft preparation|writing--review and editing|supervision	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6321022	30544604	V.M.	CRediT	methodology|writing--original draft preparation|writing--review and editing|supervision	supervision	-	Supervision	YES
6321022	30544604	Y.N.K.	CRediT	methodology|writing--original draft preparation|writing--review and editing|supervision	methodology	Performed the experiments	Methodology	YES
6321022	30544604	Y.N.K.	CRediT	methodology|writing--original draft preparation|writing--review and editing|supervision	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6321022	30544604	Y.N.K.	CRediT	methodology|writing--original draft preparation|writing--review and editing|supervision	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6321022	30544604	Y.N.K.	CRediT	methodology|writing--original draft preparation|writing--review and editing|supervision	supervision	-	Supervision	YES
4982227	27515598	CAH	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4982227	27515598	CAH	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4982227	27515598	DG	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4982227	27515598	DG	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4982227	27515598	JL	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4982227	27515598	JL	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4982227	27515598	ML	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4982227	27515598	QY	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4982227	27515598	QY	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4982227	27515598	SY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4982227	27515598	SY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4982227	27515598	SY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4982227	27515598	SY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4982227	27515598	ZZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4982227	27515598	ZZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4982227	27515598	ZZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2856570	20338027	TM	2	conceived of the study, designed the fluoroionophores, participated in its syntheses and performed the analysis	conceived of the study, designed the fluoroionophores, participated in its syntheses and performed the analysis	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
2856570	20338027	YH	2	performed the syntheses and the analysis	performed the syntheses and the analysis	Performed the experiments	Investigation	YES
2856570	20338027	YS	2	participated in its design and analysis	participated in its design and analysis	Conceived and designed the experiments	-	YES
5420569	28533791	PS	2	did the project planning and manuscript writing	did the project planning and manuscript writing	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4396984	25874774	BM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4396984	25874774	BM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4396984	25874774	BM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4396984	25874774	DP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4396984	25874774	DP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4396984	25874774	DP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4396984	25874774	JM	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4396984	25874774	LN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4396984	25874774	LN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4396984	25874774	LN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4396984	25874774	LN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4396984	25874774	RN	PLoS5	Patient selection and matching	Patient selection and matching	-	-	NO
2861024	20331845	BA	2	developed the software	developed the software	Contributed reagents/materials/analysis tools	Software	YES
2861024	20331845	DWL	2	conceived of the study, coordinated the work, carried out the analyses of spirits, beer and unrecorded alcohol, and drafted the manuscript	conceived of the study, coordinated the work, carried out the analyses of spirits, beer and unrecorded alcohol, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Project administration|Writing - Original Draft	YES
2861024	20331845	GK	2	conceived the development of the infrared sensor, and coordinated the technical work	conceived the development of the infrared sensor, and coordinated the technical work	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Project administration	YES
2861024	20331845	RG	2	carried out the analyses of wines including fermentation experiments and added the aspects of wine analysis to the draft	carried out the analyses of wines including fermentation experiments and added the aspects of wine analysis to the draft	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6321025	30545114	D.L.	CRediT	supervision	supervision	-	Supervision	YES
6321025	30545114	H.Z.	CRediT	software	software	Contributed reagents/materials/analysis tools	Software	YES
6321025	30545114	J.L.	CRediT	supervision	supervision	-	Supervision	YES
6321025	30545114	S.Q.	CRediT	software	software	Contributed reagents/materials/analysis tools	Software	YES
6321025	30545114	W.L.	CRediT	Writing-original draft preparation	Writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
6321025	30545114	Y.H.	CRediT	Writing-original draft preparation	Writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
5420576	28533788	AF	2	conceived and wrote the manuscript	conceived and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5420576	28533788	JF	2	conceived and wrote the manuscript	conceived and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5420576	28533788	MM	2	critically reviewed the manuscript	critically reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5420576	28533788	MS	2	conceived and wrote the manuscript	conceived and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
2873356	20403158	CDP	2	carried out some of the initial laboratory work and data analysis	carried out some of the initial laboratory work and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
2873356	20403158	KA	2	completed the laboratory work, all of the ms analysis and data treatment and drafted the manuscript	completed the laboratory work, all of the ms analysis and data treatment and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
2873356	20403158	MP	2	conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
2873356	20403158	SS	2	conceived the study|coordinated the study and edited the text	conceived the study	Conceived and designed the experiments	Conceptualization	YES
2873356	20403158	SS	2	conceived the study|coordinated the study and edited the text	coordinated the study and edited the text	Wrote the paper	Project administration|Writing - Review & Editing	YES
4385618	25874217	Kuo-How Huang	2	contributed equally to this work	contributed equally to this work	-	-	NO
4385618	25874217	Wei-Chou Lin	2	contributed equally to this work	contributed equally to this work	-	-	NO
5871947	29267218	K.H.	2	helped to draft and critically revise the manuscript for important intellectual content	helped to draft and critically revise the manuscript for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5871947	29267218	K.P.I.	2	designed the study, collected, analyzed, and interpreted the data, and secured funding for the study	designed the study, collected, analyzed, and interpreted the data, and secured funding for the study	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Funding acquisition|Investigation|Methodology	YES
5871947	29267218	S.W.	2	designed the study, collected, analyzed, and interpreted the data, and secured funding for the study	designed the study, collected, analyzed, and interpreted the data, and secured funding for the study	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Funding acquisition|Investigation|Methodology	YES
5871947	29267218	Y.H.	2	helped to draft and critically revise the manuscript for important intellectual content	helped to draft and critically revise the manuscript for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5871947	29267218	Y.K.	2	helped to draft and critically revise the manuscript for important intellectual content	helped to draft and critically revise the manuscript for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4982238	27515794	JHH	2	participated in conception and design of the experiments, and contributed to the writing	participated in conception and design of the experiments, and contributed to the writing	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology	YES
4982238	27515794	JS	2	analyzed the data, and were primarily responsible for writing the paper - contributing equally to the final product	analyzed the data, and were primarily responsible for writing the paper - contributing equally to the final product	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4982238	27515794	KM	2	conducted all lab experiments|analyzed the data, and were primarily responsible for writing the paper - contributing equally to the final product	conducted all lab experiments	Performed the experiments	Investigation	YES
4982238	27515794	KM	2	conducted all lab experiments|analyzed the data, and were primarily responsible for writing the paper - contributing equally to the final product	analyzed the data, and were primarily responsible for writing the paper - contributing equally to the final product	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4982238	27515794	SAW	2	participated in conception and design of the experiments, and contributed to the writing	participated in conception and design of the experiments, and contributed to the writing	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology	YES
4982238	27515794	SBC	2	participated in conception and design of the experiments, and contributed to the writing	participated in conception and design of the experiments, and contributed to the writing	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology	YES
4396988	25875585	JM	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4396988	25875585	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4396988	25875585	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4396988	25875585	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4396988	25875585	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4396988	25875585	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4396988	25875585	OH	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4396988	25875585	PK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4396988	25875585	SP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4396988	25875585	WB	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4396988	25875585	WY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4396988	25875585	WY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4396988	25875585	WY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4396988	25875585	WY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2873357	20380746	KM	2	collected data of native enzyme from bifidobacteria	collected data of native enzyme from bifidobacteria	Performed the experiments	Investigation	YES
2873357	20380746	KU	2	collected data of gene sequences and recombinant protein, and contributed to drafting the manuscript	collected data of gene sequences and recombinant protein, and contributed to drafting the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
2873357	20380746	MK	2	collected data of native enzyme from bifidobacteria	collected data of native enzyme from bifidobacteria	Performed the experiments	Investigation	YES
2873357	20380746	NS	2	generated study design and drafted manuscript	generated study design and drafted manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
2873357	20380746	SO	2	generated study design and drafted manuscript	generated study design and drafted manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
2873357	20380746	TO	2	collected data of gene sequences and recombinant protein, and contributed to drafting the manuscript	collected data of gene sequences and recombinant protein, and contributed to drafting the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4385622	25874234	Peiwei Zhang	2	contributed equally to this work	contributed equally to this work	-	-	NO
4385622	25874234	Yang Jiang	2	contributed equally to this work	contributed equally to this work	-	-	NO
5420578	28533785	AB	2	created and generated the vegetal materials|participated in the data collection and statistical analysis	created and generated the vegetal materials	Performed the experiments	Investigation	YES
5420578	28533785	AB	2	created and generated the vegetal materials|participated in the data collection and statistical analysis	participated in the data collection and statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5420578	28533785	BO	2	advisors, assisted jcjg in the field experiment design, data collection, and statistical analysis	advisors, assisted jcjg in the field experiment design, data collection, and statistical analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5420578	28533785	JCJG	2	carried out field experiments, performed statistical analysis of the data, and drafted the initial manuscript	carried out field experiments, performed statistical analysis of the data, and drafted the initial manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5420578	28533785	LFS	2	participated in the data collection and statistical analysis	participated in the data collection and statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5420578	28533785	RAM	2	created and generated the vegetal materials|advisors, assisted jcjg in the field experiment design, data collection, and statistical analysis	created and generated the vegetal materials	Performed the experiments	Investigation	YES
5420578	28533785	RAM	2	created and generated the vegetal materials|advisors, assisted jcjg in the field experiment design, data collection, and statistical analysis	advisors, assisted jcjg in the field experiment design, data collection, and statistical analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5871948	29271878	All authors	2	contributed to the drafting of the paper and approved of the final manuscript	contributed to the drafting of the paper and approved of the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6321039	30413075	A.D.	CRediT	Validation|Supervision	Validation	Performed the experiments	Validation	YES
6321039	30413075	A.D.	CRediT	Validation|Supervision	Supervision	-	Supervision	YES
6321039	30413075	C.D.	CRediT	Methodology|Investigation	Methodology	Performed the experiments	Methodology	YES
6321039	30413075	C.D.	CRediT	Methodology|Investigation	Investigation	Performed the experiments	Investigation	YES
6321039	30413075	C.I.N.	CRediT	Methodology|Software|Investigation	Methodology	Performed the experiments	Methodology	YES
6321039	30413075	C.I.N.	CRediT	Methodology|Software|Investigation	Software	Contributed reagents/materials/analysis tools	Software	YES
6321039	30413075	C.I.N.	CRediT	Methodology|Software|Investigation	Investigation	Performed the experiments	Investigation	YES
6321039	30413075	D.I.	CRediT	Conceptualization|Investigation|Writing-original draft preparation|Visualization	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6321039	30413075	D.I.	CRediT	Conceptualization|Investigation|Writing-original draft preparation|Visualization	Investigation	Performed the experiments	Investigation	YES
6321039	30413075	D.I.	CRediT	Conceptualization|Investigation|Writing-original draft preparation|Visualization	Writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
6321039	30413075	D.I.	CRediT	Conceptualization|Investigation|Writing-original draft preparation|Visualization	Visualization	Analyzed the data	Visualization	YES
6321039	30413075	G.T.	CRediT	Formal analysis|Investigation	Formal analysis	Analyzed the data	Formal analysis	YES
6321039	30413075	G.T.	CRediT	Formal analysis|Investigation	Investigation	Performed the experiments	Investigation	YES
6321039	30413075	I.D.	CRediT	Conceptualization|Validation|Writing-original draft preparation|Writing-review & editing|Supervision|Project administration|Funding acquisition	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6321039	30413075	I.D.	CRediT	Conceptualization|Validation|Writing-original draft preparation|Writing-review & editing|Supervision|Project administration|Funding acquisition	Validation	Performed the experiments	Validation	YES
6321039	30413075	I.D.	CRediT	Conceptualization|Validation|Writing-original draft preparation|Writing-review & editing|Supervision|Project administration|Funding acquisition	Writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
6321039	30413075	I.D.	CRediT	Conceptualization|Validation|Writing-original draft preparation|Writing-review & editing|Supervision|Project administration|Funding acquisition	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6321039	30413075	I.D.	CRediT	Conceptualization|Validation|Writing-original draft preparation|Writing-review & editing|Supervision|Project administration|Funding acquisition	Supervision	-	Supervision	YES
6321039	30413075	I.D.	CRediT	Conceptualization|Validation|Writing-original draft preparation|Writing-review & editing|Supervision|Project administration|Funding acquisition	Project administration	-	Project administration	YES
6321039	30413075	I.D.	CRediT	Conceptualization|Validation|Writing-original draft preparation|Writing-review & editing|Supervision|Project administration|Funding acquisition	Funding acquisition	-	Funding acquisition	YES
4396989	25875641	AX	PLoS5	Provided the data|Read and approved the manuscript	Provided the data	Contributed reagents/materials/analysis tools	Resources	YES
4396989	25875641	AX	PLoS5	Provided the data|Read and approved the manuscript	Read and approved the manuscript	-	-	NO
4396989	25875641	JL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Designed the software used in analysis|Designed the figures	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4396989	25875641	JL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Designed the software used in analysis|Designed the figures	Analyzed the data	Analyzed the data	Formal analysis	YES
4396989	25875641	JL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Designed the software used in analysis|Designed the figures	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4396989	25875641	JL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Designed the software used in analysis|Designed the figures	Designed the software used in analysis	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
4396989	25875641	JL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Designed the software used in analysis|Designed the figures	Designed the figures	Conceived and designed the experiments	Visualization	YES
4396989	25875641	LY	PLoS5	Designed the figures	Designed the figures	Conceived and designed the experiments	Visualization	YES
4396989	25875641	RL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4396989	25875641	SH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Designed the figures|Read and approved the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4396989	25875641	SH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Designed the figures|Read and approved the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4396989	25875641	SH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Designed the figures|Read and approved the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4396989	25875641	SH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Designed the figures|Read and approved the manuscript	Designed the figures	Conceived and designed the experiments	Visualization	YES
4396989	25875641	SH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Designed the figures|Read and approved the manuscript	Read and approved the manuscript	-	-	NO
4396989	25875641	YF	PLoS5	Provided the data	Provided the data	Contributed reagents/materials/analysis tools	Resources	YES
2891742	20525317	All authors	2	contributed to the writing of this manuscript	contributed to the writing of this manuscript	Wrote the paper	Writing - Original Draft	YES
2891742	20525317	MG	2	supervised the biophysical aspects of the project	supervised the biophysical aspects of the project	-	Supervision	YES
2891742	20525317	MGA	2	provided the melanosome samples and oversaw biological aspects of the project	provided the melanosome samples and oversaw biological aspects of the project	Contributed reagents/materials/analysis tools	Resources|Supervision	YES
2891742	20525317	TH	2	performed the stxm experiments, software development and data processing	performed the stxm experiments, software development and data processing	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Investigation|Software	YES
4982270	27515098	AW	PLoS52	conceived and designed the experiments|analyzed the data|wrote the first draft of the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4982270	27515098	AW	PLoS52	conceived and designed the experiments|analyzed the data|wrote the first draft of the paper	analyzed the data	Analyzed the data	Formal analysis	YES
4982270	27515098	AW	PLoS52	conceived and designed the experiments|analyzed the data|wrote the first draft of the paper	wrote the first draft of the paper	Wrote the paper	Writing - Original Draft	YES
4982270	27515098	CJR	PLoS52	conceived and designed the experiments|analyzed the data	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4982270	27515098	CJR	PLoS52	conceived and designed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
4982270	27515098	EKS	PLoS52	conducted laboratory experiments|analyzed the data|wrote the first draft of the paper	conducted laboratory experiments	Performed the experiments	Investigation	YES
4982270	27515098	EKS	PLoS52	conducted laboratory experiments|analyzed the data|wrote the first draft of the paper	analyzed the data	Analyzed the data	Formal analysis	YES
4982270	27515098	EKS	PLoS52	conducted laboratory experiments|analyzed the data|wrote the first draft of the paper	wrote the first draft of the paper	Wrote the paper	Writing - Original Draft	YES
4982270	27515098	EN	PLoS52	provided samples for analysis	provided samples for analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
4982270	27515098	FA	PLoS52	conducted laboratory experiments|analyzed the data|wrote the first draft of the paper	conducted laboratory experiments	Performed the experiments	Investigation	YES
4982270	27515098	FA	PLoS52	conducted laboratory experiments|analyzed the data|wrote the first draft of the paper	analyzed the data	Analyzed the data	Formal analysis	YES
4982270	27515098	FA	PLoS52	conducted laboratory experiments|analyzed the data|wrote the first draft of the paper	wrote the first draft of the paper	Wrote the paper	Writing - Original Draft	YES
4982270	27515098	GD	PLoS52	conducted laboratory experiments	conducted laboratory experiments	Performed the experiments	Investigation	YES
4982270	27515098	JPV	PLoS52	provided samples for analysis	provided samples for analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
4982270	27515098	KAG	PLoS52	conceived and designed the experiments|wrote the first draft of the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4982270	27515098	KAG	PLoS52	conceived and designed the experiments|wrote the first draft of the paper	wrote the first draft of the paper	Wrote the paper	Writing - Original Draft	YES
4982270	27515098	MO	PLoS52	provided samples for analysis	provided samples for analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
4982270	27515098	RBE	PLoS52	conceived and designed the experiments|analyzed the data|wrote the first draft of the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4982270	27515098	RBE	PLoS52	conceived and designed the experiments|analyzed the data|wrote the first draft of the paper	analyzed the data	Analyzed the data	Formal analysis	YES
4982270	27515098	RBE	PLoS52	conceived and designed the experiments|analyzed the data|wrote the first draft of the paper	wrote the first draft of the paper	Wrote the paper	Writing - Original Draft	YES
4982270	27515098	TF	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
4982270	27515098	VW	PLoS52	conceived and designed the experiments|provided samples for analysis	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4982270	27515098	VW	PLoS52	conceived and designed the experiments|provided samples for analysis	provided samples for analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6321048	30453628	G.R.R.	CRediT	Funding acquisition|Project administration|Supervision|Writing--review & editing	Funding acquisition	-	Funding acquisition	YES
6321048	30453628	G.R.R.	CRediT	Funding acquisition|Project administration|Supervision|Writing--review & editing	Project administration	-	Project administration	YES
6321048	30453628	G.R.R.	CRediT	Funding acquisition|Project administration|Supervision|Writing--review & editing	Supervision	-	Supervision	YES
6321048	30453628	G.R.R.	CRediT	Funding acquisition|Project administration|Supervision|Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6321048	30453628	J.D.-E.	CRediT	Data curation|Methodology|Validation|Writing--review & editing	Data curation	Analyzed the data	Data curation	YES
6321048	30453628	J.D.-E.	CRediT	Data curation|Methodology|Validation|Writing--review & editing	Methodology	Performed the experiments	Methodology	YES
6321048	30453628	J.D.-E.	CRediT	Data curation|Methodology|Validation|Writing--review & editing	Validation	Performed the experiments	Validation	YES
6321048	30453628	J.D.-E.	CRediT	Data curation|Methodology|Validation|Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6321048	30453628	J.W.Y.T.	CRediT	Methodology|Writing--review & editing	Methodology	Performed the experiments	Methodology	YES
6321048	30453628	J.W.Y.T.	CRediT	Methodology|Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6321048	30453628	K.A.S.	CRediT	Funding acquisition|Project administration|Writing--review & editing	Funding acquisition	-	Funding acquisition	YES
6321048	30453628	K.A.S.	CRediT	Funding acquisition|Project administration|Writing--review & editing	Project administration	-	Project administration	YES
6321048	30453628	K.A.S.	CRediT	Funding acquisition|Project administration|Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6321048	30453628	M.D.M.	CRediT	Conceptualization|Data curation|Formal analysis|Investigation|Methodology|Supervision|Validation|Visualization|Writing--original draft|Writing--review & editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6321048	30453628	M.D.M.	CRediT	Conceptualization|Data curation|Formal analysis|Investigation|Methodology|Supervision|Validation|Visualization|Writing--original draft|Writing--review & editing	Data curation	Analyzed the data	Data curation	YES
6321048	30453628	M.D.M.	CRediT	Conceptualization|Data curation|Formal analysis|Investigation|Methodology|Supervision|Validation|Visualization|Writing--original draft|Writing--review & editing	Formal analysis	Analyzed the data	Formal analysis	YES
6321048	30453628	M.D.M.	CRediT	Conceptualization|Data curation|Formal analysis|Investigation|Methodology|Supervision|Validation|Visualization|Writing--original draft|Writing--review & editing	Investigation	Performed the experiments	Investigation	YES
6321048	30453628	M.D.M.	CRediT	Conceptualization|Data curation|Formal analysis|Investigation|Methodology|Supervision|Validation|Visualization|Writing--original draft|Writing--review & editing	Methodology	Performed the experiments	Methodology	YES
6321048	30453628	M.D.M.	CRediT	Conceptualization|Data curation|Formal analysis|Investigation|Methodology|Supervision|Validation|Visualization|Writing--original draft|Writing--review & editing	Supervision	-	Supervision	YES
6321048	30453628	M.D.M.	CRediT	Conceptualization|Data curation|Formal analysis|Investigation|Methodology|Supervision|Validation|Visualization|Writing--original draft|Writing--review & editing	Validation	Performed the experiments	Validation	YES
6321048	30453628	M.D.M.	CRediT	Conceptualization|Data curation|Formal analysis|Investigation|Methodology|Supervision|Validation|Visualization|Writing--original draft|Writing--review & editing	Visualization	Analyzed the data	Visualization	YES
6321048	30453628	M.D.M.	CRediT	Conceptualization|Data curation|Formal analysis|Investigation|Methodology|Supervision|Validation|Visualization|Writing--original draft|Writing--review & editing	Writing--original draft	Wrote the paper	Writing - Original Draft	YES
6321048	30453628	M.D.M.	CRediT	Conceptualization|Data curation|Formal analysis|Investigation|Methodology|Supervision|Validation|Visualization|Writing--original draft|Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6321048	30453628	R.L.	CRediT	Methodology|Writing--review & editing	Methodology	Performed the experiments	Methodology	YES
6321048	30453628	R.L.	CRediT	Methodology|Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6321048	30453628	V.L.	CRediT	Methodology|Validation|Writing--review & editing	Methodology	Performed the experiments	Methodology	YES
6321048	30453628	V.L.	CRediT	Methodology|Validation|Writing--review & editing	Validation	Performed the experiments	Validation	YES
6321048	30453628	V.L.	CRediT	Methodology|Validation|Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6321048	30453628	X.W.	CRediT	Funding acquisition|Writing--review & editing	Funding acquisition	-	Funding acquisition	YES
6321048	30453628	X.W.	CRediT	Funding acquisition|Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
4396990	25874616	AE	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4396990	25874616	AE	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4396990	25874616	AE	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4396990	25874616	AM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4396990	25874616	AM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4396990	25874616	AM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4396990	25874616	AM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4396990	25874616	AV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4396990	25874616	AV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4396990	25874616	AV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4396990	25874616	AV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4396990	25874616	CSK	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4396990	25874616	DB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4396990	25874616	GB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4396990	25874616	GK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4396990	25874616	GK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4396990	25874616	GK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4396990	25874616	KF	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4396990	25874616	KK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4396990	25874616	LSS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4396990	25874616	MK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4396990	25874616	PG	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4396990	25874616	PG	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4396990	25874616	PG	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4396990	25874616	TN	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4396990	25874616	TV	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4396990	25874616	TV	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4396990	25874616	TV	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4396990	25874616	ZG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5871949	29278399	H.S.	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5871949	29278399	M.M.	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5871949	29278399	M.M.S.	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5871949	29278399	N.N.W.	PLoS52	analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5871949	29278399	N.N.W.	PLoS52	analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5871949	29278399	S.N.	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5871949	29278399	T.K.	PLoS52	analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5871949	29278399	T.K.	PLoS52	analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
2901219	20576096	All authors	2	contributed to the experimental design	contributed to the experimental design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
2901219	20576096	Feng Jiang	2	carried out nearly all of the laboratory work	carried out nearly all of the laboratory work	Performed the experiments	Investigation	YES
2901219	20576096	Haoyu Hu	2	carried out nearly all of the laboratory work	carried out nearly all of the laboratory work	Performed the experiments	Investigation	YES
2901219	20576096	Xiaocheng Cui	2	deal with the data analysis	deal with the data analysis	Analyzed the data	Formal analysis	YES
2901219	20576096	Xiaoyu Liu	2	focused on the experiment design and contributed to drafting the manuscript	focused on the experiment design and contributed to drafting the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
2901219	20576096	Xin Yao	2	deal with the data analysis	deal with the data analysis	Analyzed the data	Formal analysis	YES
5420583	28533783	AS	2	to provide an improved draft	to provide an improved draft	Wrote the paper	Writing - Original Draft	YES
5420583	28533783	CB	2	to provide an improved draft	to provide an improved draft	Wrote the paper	Writing - Original Draft	YES
5420583	28533783	DC	2	to provide an improved draft	to provide an improved draft	Wrote the paper	Writing - Original Draft	YES
5420583	28533783	JK	2	to provide an improved draft	to provide an improved draft	Wrote the paper	Writing - Original Draft	YES
5420583	28533783	RK	2	to provide an improved draft	to provide an improved draft	Wrote the paper	Writing - Original Draft	YES
5420583	28533783	RS	2	to provide an improved draft	to provide an improved draft	Wrote the paper	Writing - Original Draft	YES
5857038	29670476	AG	1	Study conception and design|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content	Study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5857038	29670476	AG	1	Study conception and design|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content	Drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
5857038	29670476	AG	1	Study conception and design|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content	Critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5857038	29670476	HM	1	Study conception and design|Acquisition of data|Statistical analysis and interpretation of data|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content	Study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5857038	29670476	HM	1	Study conception and design|Acquisition of data|Statistical analysis and interpretation of data|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content	Acquisition of data	Performed the experiments	Investigation	YES
5857038	29670476	HM	1	Study conception and design|Acquisition of data|Statistical analysis and interpretation of data|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content	Statistical analysis and interpretation of data	Analyzed the data	Formal analysis	YES
5857038	29670476	HM	1	Study conception and design|Acquisition of data|Statistical analysis and interpretation of data|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content	Drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
5857038	29670476	HM	1	Study conception and design|Acquisition of data|Statistical analysis and interpretation of data|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content	Critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5857038	29670476	MRA	1	Study conception and design|Statistical analysis and interpretation of data|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content	Study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5857038	29670476	MRA	1	Study conception and design|Statistical analysis and interpretation of data|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content	Statistical analysis and interpretation of data	Analyzed the data	Formal analysis	YES
5857038	29670476	MRA	1	Study conception and design|Statistical analysis and interpretation of data|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content	Drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
5857038	29670476	MRA	1	Study conception and design|Statistical analysis and interpretation of data|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content	Critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5857038	29670476	MRY	1	Study conception and design|Acquisition of data|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content	Study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5857038	29670476	MRY	1	Study conception and design|Acquisition of data|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content	Acquisition of data	Performed the experiments	Investigation	YES
5857038	29670476	MRY	1	Study conception and design|Acquisition of data|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content	Drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
5857038	29670476	MRY	1	Study conception and design|Acquisition of data|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content	Critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5857038	29670476	MT	1	Study conception and design|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content	Study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5857038	29670476	MT	1	Study conception and design|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content	Drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
5857038	29670476	MT	1	Study conception and design|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content	Critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4396991	25874723	AJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4396991	25874723	AJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4396991	25874723	AJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4396991	25874723	AJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4396991	25874723	BM	PLoS5	Designed the vaccine	Designed the vaccine	Conceived and designed the experiments	-	YES
4396991	25874723	BW	PLoS5	Designed the study|Designed the vaccine	Designed the study	Conceived and designed the experiments	Methodology	YES
4396991	25874723	BW	PLoS5	Designed the study|Designed the vaccine	Designed the vaccine	Conceived and designed the experiments	-	YES
4396991	25874723	CN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Designed the study	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4396991	25874723	CN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Designed the study	Performed the experiments	Performed the experiments	Investigation	YES
4396991	25874723	CN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Designed the study	Analyzed the data	Analyzed the data	Formal analysis	YES
4396991	25874723	CN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Designed the study	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4396991	25874723	CN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Designed the study	Designed the study	Conceived and designed the experiments	Methodology	YES
4396991	25874723	CO	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4396991	25874723	EFL	PLoS5	Designed the study	Designed the study	Conceived and designed the experiments	Methodology	YES
4396991	25874723	ES	PLoS5	Designed the study	Designed the study	Conceived and designed the experiments	Methodology	YES
4396991	25874723	FM	PLoS5	Designed the study	Designed the study	Conceived and designed the experiments	Methodology	YES
4396991	25874723	GB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Designed the study	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4396991	25874723	GB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Designed the study	Analyzed the data	Analyzed the data	Formal analysis	YES
4396991	25874723	GB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Designed the study	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4396991	25874723	GB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Designed the study	Designed the study	Conceived and designed the experiments	Methodology	YES
4396991	25874723	GF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4396991	25874723	GF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4396991	25874723	GF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4396991	25874723	GF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4396991	25874723	MAM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4396991	25874723	MB	PLoS5	Designed the study	Designed the study	Conceived and designed the experiments	Methodology	YES
4396991	25874723	MLR	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4396991	25874723	PE	PLoS5	Designed the vaccine	Designed the vaccine	Conceived and designed the experiments	-	YES
4396991	25874723	SA	PLoS5	Designed the study	Designed the study	Conceived and designed the experiments	Methodology	YES
4396991	25874723	VP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4396991	25874723	VP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4396991	25874723	VP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4396991	25874723	VP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4982272	27514777	BKW	2	participated in conceptualizing the experiment, carried out the experiments, performed the analysis and wrote the paper	participated in conceptualizing the experiment, carried out the experiments, performed the analysis and wrote the paper	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
4982272	27514777	DJM	2	contributed by conceptualizing the experiments and drafting the manuscript	contributed by conceptualizing the experiments and drafting the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
4982272	27514777	JAD	2	contributed by conceptualizing the experiments and drafting the manuscript	contributed by conceptualizing the experiments and drafting the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
2904757	20569488	APH	2	conceived of the study, analysed all the data, discussed the results and wrote the manuscript	conceived of the study, analysed all the data, discussed the results and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
2904757	20569488	DGM	2	conceived of the study, analysed all the data, discussed the results and wrote the manuscript	conceived of the study, analysed all the data, discussed the results and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
2904757	20569488	MPM	2	discussed the results and revised the manuscript	discussed the results and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
2904757	20569488	SAPG	2	carried out the dft calculations and wrote some portions of the paper	carried out the dft calculations and wrote some portions of the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6321060	30340413	A.A.	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
6321060	30340413	J.K.-K.	CRediT	Investigation|Writing-original draft preparation|Visualization	Investigation	Performed the experiments	Investigation	YES
6321060	30340413	J.K.-K.	CRediT	Investigation|Writing-original draft preparation|Visualization	Writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
6321060	30340413	J.K.-K.	CRediT	Investigation|Writing-original draft preparation|Visualization	Visualization	Analyzed the data	Visualization	YES
6321060	30340413	Jakub Szlek	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
6321060	30340413	Joanna Szafraniec	CRediT	Investigation|Writing-original draft preparation|Visualization	Investigation	Performed the experiments	Investigation	YES
6321060	30340413	Joanna Szafraniec	CRediT	Investigation|Writing-original draft preparation|Visualization	Writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
6321060	30340413	Joanna Szafraniec	CRediT	Investigation|Writing-original draft preparation|Visualization	Visualization	Analyzed the data	Visualization	YES
6321060	30340413	K.G.	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
6321060	30340413	M.K.	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
6321060	30340413	M.P.	CRediT	Writing-review & editing|Supervision	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6321060	30340413	M.P.	CRediT	Writing-review & editing|Supervision	Supervision	-	Supervision	YES
6321060	30340413	R.J.	CRediT	Writing-review & editing|Supervision	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6321060	30340413	R.J.	CRediT	Writing-review & editing|Supervision	Supervision	-	Supervision	YES
6321060	30340413	W.J.	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
5857039	29670477	A. Alotaibi	2	did acquisition of data|did the analysis and interpretation of data|drafted the article and revising it critically for important intellectual content	did acquisition of data	Performed the experiments	Investigation	YES
5857039	29670477	A. Alotaibi	2	did acquisition of data|did the analysis and interpretation of data|drafted the article and revising it critically for important intellectual content	did the analysis and interpretation of data	Analyzed the data	Formal analysis	YES
5857039	29670477	A. Alotaibi	2	did acquisition of data|did the analysis and interpretation of data|drafted the article and revising it critically for important intellectual content	drafted the article and revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5857039	29670477	K. Alswat	2	did the analysis and interpretation of data|approved the final version to be published	did the analysis and interpretation of data	Analyzed the data	Formal analysis	YES
5857039	29670477	K. Alswat	2	did the analysis and interpretation of data|approved the final version to be published	approved the final version to be published	-	-	NO
5857039	29670477	N. Alqurashi	2	contributions to the conception and design|approved the final version to be published	contributions to the conception and design	Conceived and designed the experiments	Conceptualization	YES
5857039	29670477	N. Alqurashi	2	contributions to the conception and design|approved the final version to be published	approved the final version to be published	-	-	NO
5857039	29670477	S. Althobiti	2	contributions to the conception and design|did acquisition of data|drafted the article and revising it critically for important intellectual content|approved the final version to be published	contributions to the conception and design	Conceived and designed the experiments	Conceptualization	YES
5857039	29670477	S. Althobiti	2	contributions to the conception and design|did acquisition of data|drafted the article and revising it critically for important intellectual content|approved the final version to be published	did acquisition of data	Performed the experiments	Investigation	YES
5857039	29670477	S. Althobiti	2	contributions to the conception and design|did acquisition of data|drafted the article and revising it critically for important intellectual content|approved the final version to be published	drafted the article and revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5857039	29670477	S. Althobiti	2	contributions to the conception and design|did acquisition of data|drafted the article and revising it critically for important intellectual content|approved the final version to be published	approved the final version to be published	-	-	NO
5857039	29670477	T. Alharthi	2	did acquisition of data|did the analysis and interpretation of data|approved the final version to be published	did acquisition of data	Performed the experiments	Investigation	YES
5857039	29670477	T. Alharthi	2	did acquisition of data|did the analysis and interpretation of data|approved the final version to be published	did the analysis and interpretation of data	Analyzed the data	Formal analysis	YES
5857039	29670477	T. Alharthi	2	did acquisition of data|did the analysis and interpretation of data|approved the final version to be published	approved the final version to be published	-	-	NO
4396992	25875484	DA	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4396992	25875484	EG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4396992	25875484	IS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4396992	25875484	JB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4396992	25875484	JG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4396992	25875484	JJ	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4396992	25875484	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4396992	25875484	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4396992	25875484	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4396992	25875484	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4396992	25875484	JO	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4396992	25875484	JR	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4396992	25875484	JS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4396992	25875484	LB	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4396992	25875484	LP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4396992	25875484	LW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4396992	25875484	MK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4396992	25875484	MS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4396992	25875484	MW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4396992	25875484	PK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4396992	25875484	PP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4396992	25875484	PP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4396992	25875484	PP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4396992	25875484	RH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4396992	25875484	RH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4396992	25875484	RH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4396992	25875484	TP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4396992	25875484	VM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4396992	25875484	VS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4396992	25875484	ZA	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5871950	29283405	All authors	2	edited and approved the final version of the manuscript	edited and approved the final version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5871950	29283405	K.K.	2	analyzed the data and edited the manuscript	analyzed the data and edited the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5871950	29283405	M.K.	2	conceived the idea for the study and contributed to the design of the research|analyzed the data and edited the manuscript	conceived the idea for the study and contributed to the design of the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5871950	29283405	M.K.	2	conceived the idea for the study and contributed to the design of the research|analyzed the data and edited the manuscript	analyzed the data and edited the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5420584	28533789	EBi	2	designed and wrote the manuscript	designed and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
5420584	28533789	RP	2	designed and wrote the manuscript	designed and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
2914664	20604934	ME	2	completed the laboratory work, data treatment and drafted the manuscript	completed the laboratory work, data treatment and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
2914664	20604934	WJB	2	coordinated the study, data analysis and edited the text	coordinated the study, data analysis and edited the text	Analyzed the data|Wrote the paper	Formal analysis|Project administration|Writing - Review & Editing	YES
2914664	20604934	YA	2	mrm data analysis	mrm data analysis	Analyzed the data	Formal analysis	YES
5857041	29670475	Ahmad Yeganeh Moghaddam	2	contributed to design, drafting, and data gathering the article	contributed to design, drafting, and data gathering the article	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Original Draft	YES
5857041	29670475	Elham Alian Fini	2	contributed to design, drafting, and data gathering the article	contributed to design, drafting, and data gathering the article	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Original Draft	YES
5857041	29670475	Mansour Sayyah	2	contribution to data analyzing	contribution to data analyzing	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5857041	29670475	Rezvan Talaee	2	contributed to design, drafting, and data gathering the article	contributed to design, drafting, and data gathering the article	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Original Draft	YES
6321070	30563197	D.O.	CRediT	Conceptualization|Supervision|Project administration	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6321070	30563197	D.O.	CRediT	Conceptualization|Supervision|Project administration	Supervision	-	Supervision	YES
6321070	30563197	D.O.	CRediT	Conceptualization|Supervision|Project administration	Project administration	-	Project administration	YES
6321070	30563197	G.C.	CRediT	Methodology|Writing-review & Editing|Funding acquisition	Methodology	Performed the experiments	Methodology	YES
6321070	30563197	G.C.	CRediT	Methodology|Writing-review & Editing|Funding acquisition	Writing-review & Editing	Wrote the paper	Writing - Review & Editing	YES
6321070	30563197	G.C.	CRediT	Methodology|Writing-review & Editing|Funding acquisition	Funding acquisition	-	Funding acquisition	YES
6321070	30563197	H.H.	CRediT	Validation|Writing-review & Editing	Validation	Performed the experiments	Validation	YES
6321070	30563197	H.H.	CRediT	Validation|Writing-review & Editing	Writing-review & Editing	Wrote the paper	Writing - Review & Editing	YES
6321070	30563197	H.Z.	CRediT	Conceptualization|Methodology|Validation|Formal analysis|Investigation|Writing-original draft preparation|Visualization	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6321070	30563197	H.Z.	CRediT	Conceptualization|Methodology|Validation|Formal analysis|Investigation|Writing-original draft preparation|Visualization	Methodology	Performed the experiments	Methodology	YES
6321070	30563197	H.Z.	CRediT	Conceptualization|Methodology|Validation|Formal analysis|Investigation|Writing-original draft preparation|Visualization	Validation	Performed the experiments	Validation	YES
6321070	30563197	H.Z.	CRediT	Conceptualization|Methodology|Validation|Formal analysis|Investigation|Writing-original draft preparation|Visualization	Formal analysis	Analyzed the data	Formal analysis	YES
6321070	30563197	H.Z.	CRediT	Conceptualization|Methodology|Validation|Formal analysis|Investigation|Writing-original draft preparation|Visualization	Investigation	Performed the experiments	Investigation	YES
6321070	30563197	H.Z.	CRediT	Conceptualization|Methodology|Validation|Formal analysis|Investigation|Writing-original draft preparation|Visualization	Writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
6321070	30563197	H.Z.	CRediT	Conceptualization|Methodology|Validation|Formal analysis|Investigation|Writing-original draft preparation|Visualization	Visualization	Analyzed the data	Visualization	YES
6321070	30563197	Y.H.	CRediT	Methodology|Writing-review & Editing	Methodology	Performed the experiments	Methodology	YES
6321070	30563197	Y.H.	CRediT	Methodology|Writing-review & Editing	Writing-review & Editing	Wrote the paper	Writing - Review & Editing	YES
4982312	27516172	CR	2	designed the study|performed bioinformatics analyses|performed qpcr tests and statistical analysis	designed the study	Conceived and designed the experiments	Methodology	YES
4982312	27516172	CR	2	designed the study|performed bioinformatics analyses|performed qpcr tests and statistical analysis	performed bioinformatics analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4982312	27516172	CR	2	designed the study|performed bioinformatics analyses|performed qpcr tests and statistical analysis	performed qpcr tests and statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4982312	27516172	SL	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
4982312	27516172	YW	2	performed bioinformatics analyses	performed bioinformatics analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4982312	27516172	ZL	2	designed the study|revised it	designed the study	Conceived and designed the experiments	Methodology	YES
4982312	27516172	ZL	2	designed the study|revised it	revised it	Wrote the paper	Writing - Review & Editing	YES
4982312	27516172	ZZ	2	carried out the treatments and hplc analysis	carried out the treatments and hplc analysis	Performed the experiments	Investigation	YES
2924338	20687941	ACE	2	ran the experiments and contributed to experimental design|assisted with the contributed to experimental design and wrote the paper with	ran the experiments and contributed to experimental design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
2924338	20687941	ACE	2	ran the experiments and contributed to experimental design|assisted with the contributed to experimental design and wrote the paper with	assisted with the contributed to experimental design and wrote the paper with	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
2924338	20687941	BAW	2	ran the experiments and contributed to experimental design	ran the experiments and contributed to experimental design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
2924338	20687941	GRB	2	contributed to experimental design and wrote the paper with	contributed to experimental design and wrote the paper with	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
2924338	20687941	WP	2	ran the experiments and contributed to experimental design	ran the experiments and contributed to experimental design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5871951	29301281	D.P.	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5871951	29301281	H.A.A.-H.	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|contributed reagents/materials/analysis tools|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5871951	29301281	H.A.A.-H.	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|contributed reagents/materials/analysis tools|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5871951	29301281	H.A.A.-H.	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|contributed reagents/materials/analysis tools|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5871951	29301281	H.A.A.-H.	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|contributed reagents/materials/analysis tools|wrote the paper	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5871951	29301281	H.A.A.-H.	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|contributed reagents/materials/analysis tools|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5871951	29301281	K.B.H.	PLoS52	conceived and designed the experiments|contributed reagents/materials/analysis tools|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5871951	29301281	K.B.H.	PLoS52	conceived and designed the experiments|contributed reagents/materials/analysis tools|wrote the paper	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5871951	29301281	K.B.H.	PLoS52	conceived and designed the experiments|contributed reagents/materials/analysis tools|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5871951	29301281	M.A.-H.	PLoS52	analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5871951	29301281	M.A.-H.	PLoS52	analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5871951	29301281	M.L.D.	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
4396993	25874381	AM	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4396993	25874381	AM	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4396993	25874381	M. Rajerison	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4396993	25874381	M. Ratsitorahina	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4396993	25874381	M. Ratsitorahinia	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4396993	25874381	S. Rahelinirina	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4396993	25874381	S. Rahelinirina	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4396993	25874381	S. Rajatonirina	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4396993	25874381	S. Rajatonirina	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4396993	25874381	S. Rajatonirina	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4396993	25874381	S. Rajatonirina	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4396993	25874381	VR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4396993	25874381	VR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4396993	25874381	VR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4396993	25874381	VR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5857042	29670473	Lejla Hasanbegovic	2	carried out research and participated in the writing of the paper	carried out research and participated in the writing of the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5857042	29670473	Nedeljka Sljivo	2	participated in the writing of the paper and shes in charge of correspondence	participated in the writing of the paper and shes in charge of correspondence	Wrote the paper	Writing - Original Draft	YES
5385181	28391483	AKS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5385181	28391483	AKS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5385181	28391483	CMM	PLoS5	Contributed reagents/materials	Contributed reagents/materials	Contributed reagents/materials/analysis tools	Resources	YES
5385181	28391483	RNP	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
5385181	28391483	RNP	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5385181	28391483	RNP	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5385181	28391483	SS	PLoS5	Contributed reagents/materials	Contributed reagents/materials	Contributed reagents/materials/analysis tools	Resources	YES
5385181	28391483	TKM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5420586	28533786	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5420586	28533786	CS	2	have finished phenotyping and genotyping of f2 progeny, participated in developing the f2 population, and statistical analysis of data	have finished phenotyping and genotyping of f2 progeny, participated in developing the f2 population, and statistical analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5420586	28533786	JZ	2	have provided advices on designing experiment	have provided advices on designing experiment	Conceived and designed the experiments	Methodology	YES
5420586	28533786	SG	2	have provided advices on designing experiment	have provided advices on designing experiment	Conceived and designed the experiments	Methodology	YES
5420586	28533786	SL	2	have provided advices on designing experiment	have provided advices on designing experiment	Conceived and designed the experiments	Methodology	YES
5420586	28533786	SX	2	have finished analyzing the data, evaluating the qtl mapping methods, and drafted the manuscript	have finished analyzing the data, evaluating the qtl mapping methods, and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5420586	28533786	WW	2	have finished phenotyping and genotyping of f2 progeny, participated in developing the f2 population, and statistical analysis of data	have finished phenotyping and genotyping of f2 progeny, participated in developing the f2 population, and statistical analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5871953	29320394	All authors	2	are involved in the direct patient care, literature search and drafting of manuscript	are involved in the direct patient care, literature search and drafting of manuscript	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4983006	27519173	All authors	2	reviewed and tested the software	reviewed and tested the software	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
4983006	27519173	HS	2	was involved in preparing figure images, updating web page design, web deployment, and database migration	was involved in preparing figure images, updating web page design, web deployment, and database migration	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Software|Visualization	YES
4983006	27519173	ISY	2	wrote the manuscript, which was reviewed by all authors	wrote the manuscript, which was reviewed by all authors	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
2955580	20858266	AM	2	conceived the study and helped draft the manuscript|performed the coordination of the study, and worked on the data analysis and interpretation	conceived the study and helped draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
2955580	20858266	AM	2	conceived the study and helped draft the manuscript|performed the coordination of the study, and worked on the data analysis and interpretation	performed the coordination of the study, and worked on the data analysis and interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Project administration	YES
2955580	20858266	BT	2	conceived the study and helped draft the manuscript|performed the coordination of the study, and worked on the data analysis and interpretation	conceived the study and helped draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
2955580	20858266	BT	2	conceived the study and helped draft the manuscript|performed the coordination of the study, and worked on the data analysis and interpretation	performed the coordination of the study, and worked on the data analysis and interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Project administration	YES
2955580	20858266	HA	2	conceived the study and helped draft the manuscript|performed the coordination of the study, and worked on the data analysis and interpretation	conceived the study and helped draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
2955580	20858266	HA	2	conceived the study and helped draft the manuscript|performed the coordination of the study, and worked on the data analysis and interpretation	performed the coordination of the study, and worked on the data analysis and interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Project administration	YES
2955580	20858266	JC	2	conceived the study and helped draft the manuscript|performed the coordination of the study, and worked on the data analysis and interpretation	conceived the study and helped draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
2955580	20858266	JC	2	conceived the study and helped draft the manuscript|performed the coordination of the study, and worked on the data analysis and interpretation	performed the coordination of the study, and worked on the data analysis and interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Project administration	YES
2955580	20858266	JMD	2	performed the hd and hs-spme extractions, obtained the essential oils and the volatile fractions, and participated in the data analysis	performed the hd and hs-spme extractions, obtained the essential oils and the volatile fractions, and participated in the data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
2955580	20858266	MAD	2	collected the plant material|performed the hd and hs-spme extractions, obtained the essential oils and the volatile fractions, and participated in the data analysis|conceived the study and helped draft the manuscript	collected the plant material	Performed the experiments	Investigation	YES
2955580	20858266	MAD	2	collected the plant material|performed the hd and hs-spme extractions, obtained the essential oils and the volatile fractions, and participated in the data analysis|conceived the study and helped draft the manuscript	performed the hd and hs-spme extractions, obtained the essential oils and the volatile fractions, and participated in the data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
2955580	20858266	MAD	2	collected the plant material|performed the hd and hs-spme extractions, obtained the essential oils and the volatile fractions, and participated in the data analysis|conceived the study and helped draft the manuscript	conceived the study and helped draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
2955580	20858266	ND	2	performed the hd and hs-spme extractions, obtained the essential oils and the volatile fractions, and participated in the data analysis	performed the hd and hs-spme extractions, obtained the essential oils and the volatile fractions, and participated in the data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5857043	29670478	Dz.K.	2	revised manuscript and gave final approval of the final version to be submitted	revised manuscript and gave final approval of the final version to be submitted	Wrote the paper	Writing - Review & Editing	YES
5857043	29670478	N.C.	2	revised manuscript and gave final approval of the version to be submitted	revised manuscript and gave final approval of the version to be submitted	Wrote the paper	Writing - Review & Editing	YES
4396994	25874895	AJG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4396994	25874895	AJG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4396994	25874895	AJG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4396994	25874895	AJG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4396994	25874895	AJG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4396994	25874895	CAM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4396994	25874895	DG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4396994	25874895	DG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4396994	25874895	DG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4396994	25874895	SBK	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4396994	25874895	SBK	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4396994	25874895	SBK	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6321096	30322124	A.A.E.	PLoS52	conceived and designed the experiments|analyzed the data generated|reviewed the paper|was the study lead and acted as the corresponding author	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6321096	30322124	A.A.E.	PLoS52	conceived and designed the experiments|analyzed the data generated|reviewed the paper|was the study lead and acted as the corresponding author	analyzed the data generated	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6321096	30322124	A.A.E.	PLoS52	conceived and designed the experiments|analyzed the data generated|reviewed the paper|was the study lead and acted as the corresponding author	reviewed the paper	Wrote the paper	Writing - Review & Editing	YES
6321096	30322124	A.A.E.	PLoS52	conceived and designed the experiments|analyzed the data generated|reviewed the paper|was the study lead and acted as the corresponding author	was the study lead and acted as the corresponding author	-	-	NO
6321096	30322124	C.S.C.	PLoS52	conceived and designed the experiments|analyzed the data generated|reviewed the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6321096	30322124	C.S.C.	PLoS52	conceived and designed the experiments|analyzed the data generated|reviewed the paper	analyzed the data generated	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6321096	30322124	C.S.C.	PLoS52	conceived and designed the experiments|analyzed the data generated|reviewed the paper	reviewed the paper	Wrote the paper	Writing - Review & Editing	YES
6321096	30322124	L.K.Y.	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data generated|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6321096	30322124	L.K.Y.	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data generated|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
6321096	30322124	L.K.Y.	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data generated|wrote the paper	analyzed the data generated	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6321096	30322124	L.K.Y.	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data generated|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6321096	30322124	T.O.B.O.	PLoS52	confirmed the data of one experiment	confirmed the data of one experiment	-	-	NO
5871954	29324681	Ralph Santos-Oliveira	7	Study conception and design: Acquisition of data: Analysis and interpretation of data: Drafting of manuscript: Critical revision	Study conception and design: Acquisition of data: Analysis and interpretation of data: Drafting of manuscript: Critical revision	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5871954	29324681	Thais Braga Ligero	7	Study conception and design: Acquisition of data: Analysis and interpretation of data: Drafting of manuscript: Critical revision	Study conception and design: Acquisition of data: Analysis and interpretation of data: Drafting of manuscript: Critical revision	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
2987902	20977733	HL	2	proposed and supervised the program, and participated in data analysis and draft reversion	proposed and supervised the program, and participated in data analysis and draft reversion	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Supervision|Writing - Original Draft	YES
2987902	20977733	PH	2	coordinated the study and modified the text	coordinated the study and modified the text	-	Project administration	YES
2987902	20977733	YS	2	carried out the experimental work, participated in data collection and manuscript drafting	carried out the experimental work, participated in data collection and manuscript drafting	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
2987902	20977733	YT	2	participated in the design of this study and analyzed experimental data	participated in the design of this study and analyzed experimental data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5420590	28533790	KT	PLoS52	designed the research and drafted the manuscript	designed the research and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5420590	28533790	LL	PLoS52	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5420590	28533790	MC	PLoS52	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5420590	28533790	PL	PLoS52	carried out vector construct, expression analysis, transgene plant generation, subcellular localization and yeast assay	carried out vector construct, expression analysis, transgene plant generation, subcellular localization and yeast assay	Performed the experiments	Investigation	YES
5420590	28533790	PS	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5420590	28533790	QH	PLoS52	carried out vector construct, expression analysis, transgene plant generation, subcellular localization and yeast assay	carried out vector construct, expression analysis, transgene plant generation, subcellular localization and yeast assay	Performed the experiments	Investigation	YES
5420590	28533790	QP	PLoS52	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5420590	28533790	QS	PLoS52	carried out vector construct, expression analysis, transgene plant generation, subcellular localization and yeast assay	carried out vector construct, expression analysis, transgene plant generation, subcellular localization and yeast assay	Performed the experiments	Investigation	YES
5420590	28533790	TY	PLoS52	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5420590	28533790	XF	PLoS52	designed the research and drafted the manuscript|performed the experiments|carried out vector construct, expression analysis, transgene plant generation, subcellular localization and yeast assay	designed the research and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5420590	28533790	XF	PLoS52	designed the research and drafted the manuscript|performed the experiments|carried out vector construct, expression analysis, transgene plant generation, subcellular localization and yeast assay	performed the experiments	Performed the experiments	Investigation	YES
5420590	28533790	XF	PLoS52	designed the research and drafted the manuscript|performed the experiments|carried out vector construct, expression analysis, transgene plant generation, subcellular localization and yeast assay	carried out vector construct, expression analysis, transgene plant generation, subcellular localization and yeast assay	Performed the experiments	Investigation	YES
5420590	28533790	XH	PLoS52	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5420590	28533790	XS	PLoS52	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5420590	28533790	YM	PLoS52	carried out vector construct, expression analysis, transgene plant generation, subcellular localization and yeast assay	carried out vector construct, expression analysis, transgene plant generation, subcellular localization and yeast assay	Performed the experiments	Investigation	YES
5420590	28533790	YT	PLoS52	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5420590	28533790	YW	PLoS52	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5857052	29670480	DS	2	the idea to do a meta-analysis	the idea to do a meta-analysis	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
5857052	29670480	GBB	2	the idea to do a meta-analysis	the idea to do a meta-analysis	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
5857052	29670480	SNK	2	prepared the first draft of the manuscript which was finalized jointly by all authors|is the guarantor of the work	prepared the first draft of the manuscript which was finalized jointly by all authors	Wrote the paper	Writing - Original Draft	YES
5857052	29670480	SNK	2	prepared the first draft of the manuscript which was finalized jointly by all authors|is the guarantor of the work	is the guarantor of the work	-	-	NO
3004896	21143843	HL	2	completed the molecular design, the arrangement of the work and modification of the manuscript	completed the molecular design, the arrangement of the work and modification of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
3004896	21143843	JL	2	carried out the synthetic experiments and drafted the manuscript	carried out the synthetic experiments and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3004896	21143843	YL	2	participated in the separation and purification of compounds, acquisition of data, and collection of literature and helped to draft the manuscript	participated in the separation and purification of compounds, acquisition of data, and collection of literature and helped to draft the manuscript	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4983018	27519500	GL	2	designed the experiments and wrote the paper|did the data analysis	designed the experiments and wrote the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4983018	27519500	GL	2	designed the experiments and wrote the paper|did the data analysis	did the data analysis	Analyzed the data	Formal analysis	YES
4983018	27519500	KZ	2	designed the experiments and wrote the paper|did the data analysis	designed the experiments and wrote the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4983018	27519500	KZ	2	designed the experiments and wrote the paper|did the data analysis	did the data analysis	Analyzed the data	Formal analysis	YES
4983018	27519500	LLG	2	designed the experiments and wrote the paper	designed the experiments and wrote the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4983018	27519500	XS	2	collected the samples and constructed the libraries	collected the samples and constructed the libraries	Performed the experiments	Investigation	YES
3124287	21747819	All authors	2	contributed to the design of the workflow|contributed to drafting the manuscript and approved the final version	contributed to the design of the workflow	Conceived and designed the experiments|Performed the experiments	Methodology	YES
3124287	21747819	All authors	2	contributed to the design of the workflow|contributed to drafting the manuscript and approved the final version	contributed to drafting the manuscript and approved the final version	Wrote the paper	Writing - Original Draft	YES
3124287	21747819	C. Bendtsen	2	designed the study|analyzed the images|analyzed the results	designed the study	Conceived and designed the experiments	Methodology	YES
3124287	21747819	C. Bendtsen	2	designed the study|analyzed the images|analyzed the results	analyzed the images	Analyzed the data	Formal analysis|Visualization	YES
3124287	21747819	C. Bendtsen	2	designed the study|analyzed the images|analyzed the results	analyzed the results	Analyzed the data	Formal analysis	YES
3124287	21747819	G. Binnig	2	implemented the workflow	implemented the workflow	Performed the experiments	Investigation|Methodology	YES
3124287	21747819	G. Schmidt	2	implemented the workflow	implemented the workflow	Performed the experiments	Investigation|Methodology	YES
3124287	21747819	M. Kietzmann	2	implemented the workflow|analyzed the images	implemented the workflow	Performed the experiments	Investigation|Methodology	YES
3124287	21747819	M. Kietzmann	2	implemented the workflow|analyzed the images	analyzed the images	Analyzed the data	Formal analysis|Visualization	YES
3124287	21747819	P. D. Mozley	2	designed the study|analyzed the results	designed the study	Conceived and designed the experiments	Methodology	YES
3124287	21747819	P. D. Mozley	2	designed the study|analyzed the results	analyzed the results	Analyzed the data	Formal analysis	YES
3124287	21747819	R. Korn	2	implemented the workflow	implemented the workflow	Performed the experiments	Investigation|Methodology	YES
5871955	29337850	Ali I. Al-Gareeb	2	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5871955	29337850	All authors	2	contributed in wrote of the paper	contributed in wrote of the paper	Wrote the paper	Writing - Original Draft	YES
5871955	29337850	Hayder M. Al-Kuraishy	2	conceived and designed the study experiment	conceived and designed the study experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5857053	29670474	all authors	2	finally approved the manuscript and agreed to be accountable for all aspects of the work	finally approved the manuscript and agreed to be accountable for all aspects of the work	-	-	NO
5420594	28533792	AP	2	provided the xylem anatomical data	provided the xylem anatomical data	Contributed reagents/materials/analysis tools	Resources	YES
5420594	28533792	DC	2	provided the xylem anatomical data|wrote the article with input from all authors that finally read and approved the submitted version	provided the xylem anatomical data	Contributed reagents/materials/analysis tools	Resources	YES
5420594	28533792	DC	2	provided the xylem anatomical data|wrote the article with input from all authors that finally read and approved the submitted version	wrote the article with input from all authors that finally read and approved the submitted version	Wrote the paper	Writing - Original Draft	YES
5420594	28533792	GP	2	provided the xylem anatomical data	provided the xylem anatomical data	Contributed reagents/materials/analysis tools	Resources	YES
5420594	28533792	GvA	2	wrote the article with input from all authors that finally read and approved the submitted version	wrote the article with input from all authors that finally read and approved the submitted version	Wrote the paper	Writing - Original Draft	YES
5420594	28533792	MC	2	designed the study and analyzed the data with input from all authors|provided the xylem anatomical data|wrote the article with input from all authors that finally read and approved the submitted version	designed the study and analyzed the data with input from all authors	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5420594	28533792	MC	2	designed the study and analyzed the data with input from all authors|provided the xylem anatomical data|wrote the article with input from all authors that finally read and approved the submitted version	provided the xylem anatomical data	Contributed reagents/materials/analysis tools	Resources	YES
5420594	28533792	MC	2	designed the study and analyzed the data with input from all authors|provided the xylem anatomical data|wrote the article with input from all authors that finally read and approved the submitted version	wrote the article with input from all authors that finally read and approved the submitted version	Wrote the paper	Writing - Original Draft	YES
4397011	25875009	BB	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4397011	25875009	BB	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397011	25875009	IP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397011	25875009	IP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397011	25875009	IP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397011	25875009	IP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397011	25875009	IP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397011	25875009	LG	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4397011	25875009	LG	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4397011	25875009	LG	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397011	25875009	SH	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397011	25875009	SH	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3349324	22619620	D. Ptasinska-Wnuk	2	contributed equally to this work	contributed equally to this work	-	-	NO
3349324	22619620	H. Lawnicka	2	contributed equally to this work	contributed equally to this work	-	-	NO
4385637	25874207	Adolfo Garrido	4	Phantom design and construction were done by	Phantom design and construction were done by	Conceived and designed the experiments|Performed the experiments	Investigation	YES
4385637	25874207	Agustin Castiella	4	The study design was done by|Data analysis interpretation was done by|Paper preparation was done by	The study design was done by	Conceived and designed the experiments	Methodology	YES
4385637	25874207	Agustin Castiella	4	The study design was done by|Data analysis interpretation was done by|Paper preparation was done by	Data analysis interpretation was done by	Analyzed the data	Formal analysis	YES
4385637	25874207	Agustin Castiella	4	The study design was done by|Data analysis interpretation was done by|Paper preparation was done by	Paper preparation was done by	-	-	NO
4385637	25874207	Alfonso Casado	4	The literature research was done by|Phantom design and construction were done by	The literature research was done by	-	Formal analysis	YES
4385637	25874207	Alfonso Casado	4	The literature research was done by|Phantom design and construction were done by	Phantom design and construction were done by	Conceived and designed the experiments|Performed the experiments	Investigation	YES
4385637	25874207	Ana Belen Asensio	4	Data analysis interpretation was done by|Statistical analysis was performed by	Data analysis interpretation was done by	Analyzed the data	Formal analysis	YES
4385637	25874207	Ana Belen Asensio	4	Data analysis interpretation was done by|Statistical analysis was performed by	Statistical analysis was performed by	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4385637	25874207	Aranzazu Moyua	4	The study design was done by|Data acquisition (Osatek-San Sebastian) and MSV Data acquisition  were done by	The study design was done by	Conceived and designed the experiments	Methodology	YES
4385637	25874207	Aranzazu Moyua	4	The study design was done by|Data acquisition (Osatek-San Sebastian) and MSV Data acquisition  were done by	Data acquisition (Osatek-San Sebastian) and MSV Data acquisition  were done by	Performed the experiments	Investigation	YES
4385637	25874207	Emma Salvador	4	The study design was done by|Data acquisition (Osatek-San Sebastian) and MSV Data acquisition  were done by	The study design was done by	Conceived and designed the experiments	Methodology	YES
4385637	25874207	Emma Salvador	4	The study design was done by|Data acquisition (Osatek-San Sebastian) and MSV Data acquisition  were done by	Data acquisition (Osatek-San Sebastian) and MSV Data acquisition  were done by	Performed the experiments	Investigation	YES
4385637	25874207	Jesus Banales	4	Data analysis interpretation was done by|Paper preparation was done by	Data analysis interpretation was done by	Analyzed the data	Formal analysis	YES
4385637	25874207	Jesus Banales	4	Data analysis interpretation was done by|Paper preparation was done by	Paper preparation was done by	-	-	NO
4385637	25874207	Jose I. Emparanza	4	The study design was done by|Statistical analysis was performed by|Paper preparation was done by|Phantom design and construction were done by	The study design was done by	Conceived and designed the experiments	Methodology	YES
4385637	25874207	Jose I. Emparanza	4	The study design was done by|Statistical analysis was performed by|Paper preparation was done by|Phantom design and construction were done by	Statistical analysis was performed by	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4385637	25874207	Jose I. Emparanza	4	The study design was done by|Statistical analysis was performed by|Paper preparation was done by|Phantom design and construction were done by	Paper preparation was done by	-	-	NO
4385637	25874207	Jose I. Emparanza	4	The study design was done by|Statistical analysis was performed by|Paper preparation was done by|Phantom design and construction were done by	Phantom design and construction were done by	Conceived and designed the experiments|Performed the experiments	Investigation	YES
4385637	25874207	Jose Maria Alustiza	4	The study design was done by|The literature research was done by|Data analysis interpretation was done by|Paper preparation was done by|Phantom design and construction were done by	The study design was done by	Conceived and designed the experiments	Methodology	YES
4385637	25874207	Jose Maria Alustiza	4	The study design was done by|The literature research was done by|Data analysis interpretation was done by|Paper preparation was done by|Phantom design and construction were done by	The literature research was done by	-	Formal analysis	YES
4385637	25874207	Jose Maria Alustiza	4	The study design was done by|The literature research was done by|Data analysis interpretation was done by|Paper preparation was done by|Phantom design and construction were done by	Data analysis interpretation was done by	Analyzed the data	Formal analysis	YES
4385637	25874207	Jose Maria Alustiza	4	The study design was done by|The literature research was done by|Data analysis interpretation was done by|Paper preparation was done by|Phantom design and construction were done by	Paper preparation was done by	-	-	NO
4385637	25874207	Jose Maria Alustiza	4	The study design was done by|The literature research was done by|Data analysis interpretation was done by|Paper preparation was done by|Phantom design and construction were done by	Phantom design and construction were done by	Conceived and designed the experiments|Performed the experiments	Investigation	YES
4385637	25874207	Lourdes Jauregui	4	The study design was done by|Data acquisition (Osatek-San Sebastian) and MSV Data acquisition  were done by	The study design was done by	Conceived and designed the experiments	Methodology	YES
4385637	25874207	Lourdes Jauregui	4	The study design was done by|Data acquisition (Osatek-San Sebastian) and MSV Data acquisition  were done by	Data acquisition (Osatek-San Sebastian) and MSV Data acquisition  were done by	Performed the experiments	Investigation	YES
4385637	25874207	Miguel Zarco	4	The study design was done by|Data acquisition (Osatek-San Sebastian) and MSV Data acquisition  were done by	The study design was done by	Conceived and designed the experiments	Methodology	YES
4385637	25874207	Miguel Zarco	4	The study design was done by|Data acquisition (Osatek-San Sebastian) and MSV Data acquisition  were done by	Data acquisition (Osatek-San Sebastian) and MSV Data acquisition  were done by	Performed the experiments	Investigation	YES
4385637	25874207	Nerea Garcia	4	The literature research was done by|Data analysis interpretation was done by|Statistical analysis was performed by	The literature research was done by	-	Formal analysis	YES
4385637	25874207	Nerea Garcia	4	The literature research was done by|Data analysis interpretation was done by|Statistical analysis was performed by	Data analysis interpretation was done by	Analyzed the data	Formal analysis	YES
4385637	25874207	Nerea Garcia	4	The literature research was done by|Data analysis interpretation was done by|Statistical analysis was performed by	Statistical analysis was performed by	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4385637	25874207	Ohiana Vicente	4	The study design was done by|Data acquisition (Osatek-San Sebastian) and MSV Data acquisition  were done by	The study design was done by	Conceived and designed the experiments	Methodology	YES
4385637	25874207	Ohiana Vicente	4	The study design was done by|Data acquisition (Osatek-San Sebastian) and MSV Data acquisition  were done by	Data acquisition (Osatek-San Sebastian) and MSV Data acquisition  were done by	Performed the experiments	Investigation	YES
4385637	25874207	Pablo Aldazabal	4	The study design was done by|Data analysis interpretation was done by|Phantom design and construction were done by	The study design was done by	Conceived and designed the experiments	Methodology	YES
4385637	25874207	Pablo Aldazabal	4	The study design was done by|Data analysis interpretation was done by|Phantom design and construction were done by	Data analysis interpretation was done by	Analyzed the data	Formal analysis	YES
4385637	25874207	Pablo Aldazabal	4	The study design was done by|Data analysis interpretation was done by|Phantom design and construction were done by	Phantom design and construction were done by	Conceived and designed the experiments|Performed the experiments	Investigation	YES
4385637	25874207	Xabier Arozena	4	The study design was done by|Data acquisition (Osatek-San Sebastian) and MSV Data acquisition  were done by	The study design was done by	Conceived and designed the experiments	Methodology	YES
4385637	25874207	Xabier Arozena	4	The study design was done by|Data acquisition (Osatek-San Sebastian) and MSV Data acquisition  were done by	Data acquisition (Osatek-San Sebastian) and MSV Data acquisition  were done by	Performed the experiments	Investigation	YES
5871956	29361704	C.F.	2	followed patients and analyzed the data	followed patients and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5871956	29361704	E.A.	2	followed patients and analyzed the data	followed patients and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5871956	29361704	E.B.	2	conceived and designed the study protocol	conceived and designed the study protocol	Conceived and designed the experiments	Conceptualization|Methodology	YES
5871956	29361704	E.L.	2	followed patients and analyzed the data	followed patients and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5871956	29361704	G.G.	2	followed patients and analyzed the data	followed patients and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5871956	29361704	M.F.	2	conceived and designed the study protocol and analyzed the data	conceived and designed the study protocol and analyzed the data	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
5871956	29361704	M.T.	2	followed patients and analyzed the data	followed patients and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5871956	29361704	P.R.	2	followed patients and analyzed the data	followed patients and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4983039	27519564	CC	2	design the algorithm|prepared the manuscript	design the algorithm	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
4983039	27519564	CC	2	design the algorithm|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
4983039	27519564	CCL	2	design the algorithm|prepared the manuscript	design the algorithm	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
4983039	27519564	CCL	2	design the algorithm|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
4983039	27519564	CCY	2	carried out the implementation of the algorithm|prepared the manuscript	carried out the implementation of the algorithm	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
4983039	27519564	CCY	2	carried out the implementation of the algorithm|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
4983039	27519564	EHA	2	carried out the implementation of the algorithm|prepared the manuscript	carried out the implementation of the algorithm	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
4983039	27519564	EHA	2	carried out the implementation of the algorithm|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
4983039	27519564	JWC	2	contributed to the literature study	contributed to the literature study	-	-	NO
4983039	27519564	MG	2	prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
4983039	27519564	MHC	2	participated in the design of the web server	participated in the design of the web server	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
4983039	27519564	WYW	2	participated in the design of the web server	participated in the design of the web server	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
3024920	21208421	DS	2	involved in acquisition of data, analysis and interpretation of data	involved in acquisition of data, analysis and interpretation of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3024920	21208421	HG	2	has made substantial contributions to conception and design, acquisition of data, analysis and interpretation of data, involved in drafting the manuscript and revising it critically for important intellectual content	has made substantial contributions to conception and design, acquisition of data, analysis and interpretation of data, involved in drafting the manuscript and revising it critically for important intellectual content	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
3024920	21208421	HQ	2	involved in acquisition of data, analysis and interpretation of data	involved in acquisition of data, analysis and interpretation of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3024920	21208421	HY	2	revised it critically for important intellectual content	revised it critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
3024920	21208421	JT	2	involved in acquisition of data, analysis and interpretation of data	involved in acquisition of data, analysis and interpretation of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3024920	21208421	JW	2	involved in acquisition of data, analysis and interpretation of data	involved in acquisition of data, analysis and interpretation of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3024920	21208421	SS	2	revised it critically for important intellectual content	revised it critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
3024920	21208421	XC	2	revised it critically for important intellectual content	revised it critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
3024920	21208421	XL	2	revised it critically for important intellectual content	revised it critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
3024920	21208421	ZL	2	revised it critically for important intellectual content	revised it critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5857054	29670481	Dz.J.	2	gave substantial contributions to the conception, design, acquisition, analysis, and interpretation of data, revised it critically and gave final approval of the version to be published|gave agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	gave substantial contributions to the conception, design, acquisition, analysis, and interpretation of data, revised it critically and gave final approval of the version to be published	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Resources|Writing - Review & Editing	YES
5857054	29670481	Dz.J.	2	gave substantial contributions to the conception, design, acquisition, analysis, and interpretation of data, revised it critically and gave final approval of the version to be published|gave agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	gave agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	-	-	NO
5857054	29670481	E.B.	2	gave substantial contributions to the conception, design, acquisition, analysis, and interpretation of data, revised it critically and gave final approval of the version to be published|gave agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	gave substantial contributions to the conception, design, acquisition, analysis, and interpretation of data, revised it critically and gave final approval of the version to be published	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Resources|Writing - Review & Editing	YES
5857054	29670481	E.B.	2	gave substantial contributions to the conception, design, acquisition, analysis, and interpretation of data, revised it critically and gave final approval of the version to be published|gave agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	gave agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	-	-	NO
6321128	30400382	A.B.	CRediT	methodology|formal analysis	methodology	Performed the experiments	Methodology	YES
6321128	30400382	A.B.	CRediT	methodology|formal analysis	formal analysis	Analyzed the data	Formal analysis	YES
6321128	30400382	A.S.-R.	CRediT	Conceptualization|methodology|formal analysis|investigation|writing--original draft preparation|project administration	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6321128	30400382	A.S.-R.	CRediT	Conceptualization|methodology|formal analysis|investigation|writing--original draft preparation|project administration	methodology	Performed the experiments	Methodology	YES
6321128	30400382	A.S.-R.	CRediT	Conceptualization|methodology|formal analysis|investigation|writing--original draft preparation|project administration	formal analysis	Analyzed the data	Formal analysis	YES
6321128	30400382	A.S.-R.	CRediT	Conceptualization|methodology|formal analysis|investigation|writing--original draft preparation|project administration	investigation	Performed the experiments	Investigation	YES
6321128	30400382	A.S.-R.	CRediT	Conceptualization|methodology|formal analysis|investigation|writing--original draft preparation|project administration	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6321128	30400382	A.S.-R.	CRediT	Conceptualization|methodology|formal analysis|investigation|writing--original draft preparation|project administration	project administration	-	Project administration	YES
6321128	30400382	A.S.V.	CRediT	methodology|formal analysis|Writing - review & editing	methodology	Performed the experiments	Methodology	YES
6321128	30400382	A.S.V.	CRediT	methodology|formal analysis|Writing - review & editing	formal analysis	Analyzed the data	Formal analysis	YES
6321128	30400382	A.S.V.	CRediT	methodology|formal analysis|Writing - review & editing	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
6321128	30400382	C.E.	CRediT	methodology|formal analysis	methodology	Performed the experiments	Methodology	YES
6321128	30400382	C.E.	CRediT	methodology|formal analysis	formal analysis	Analyzed the data	Formal analysis	YES
6321128	30400382	C.G.	CRediT	methodology|formal analysis	methodology	Performed the experiments	Methodology	YES
6321128	30400382	C.G.	CRediT	methodology|formal analysis	formal analysis	Analyzed the data	Formal analysis	YES
6321128	30400382	C.P.R.	CRediT	Conceptualization|methodology|formal analysis|Writing - review & editing|supervision|project administration	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6321128	30400382	C.P.R.	CRediT	Conceptualization|methodology|formal analysis|Writing - review & editing|supervision|project administration	methodology	Performed the experiments	Methodology	YES
6321128	30400382	C.P.R.	CRediT	Conceptualization|methodology|formal analysis|Writing - review & editing|supervision|project administration	formal analysis	Analyzed the data	Formal analysis	YES
6321128	30400382	C.P.R.	CRediT	Conceptualization|methodology|formal analysis|Writing - review & editing|supervision|project administration	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
6321128	30400382	C.P.R.	CRediT	Conceptualization|methodology|formal analysis|Writing - review & editing|supervision|project administration	supervision	-	Supervision	YES
6321128	30400382	C.P.R.	CRediT	Conceptualization|methodology|formal analysis|Writing - review & editing|supervision|project administration	project administration	-	Project administration	YES
6321128	30400382	J.F.P.	CRediT	methodology|formal analysis|Writing - review & editing	methodology	Performed the experiments	Methodology	YES
6321128	30400382	J.F.P.	CRediT	methodology|formal analysis|Writing - review & editing	formal analysis	Analyzed the data	Formal analysis	YES
6321128	30400382	J.F.P.	CRediT	methodology|formal analysis|Writing - review & editing	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
6321128	30400382	J.M.	CRediT	methodology|formal analysis|Writing - review & editing|supervision	methodology	Performed the experiments	Methodology	YES
6321128	30400382	J.M.	CRediT	methodology|formal analysis|Writing - review & editing|supervision	formal analysis	Analyzed the data	Formal analysis	YES
6321128	30400382	J.M.	CRediT	methodology|formal analysis|Writing - review & editing|supervision	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
6321128	30400382	J.M.	CRediT	methodology|formal analysis|Writing - review & editing|supervision	supervision	-	Supervision	YES
6321128	30400382	L.A.	CRediT	methodology|formal analysis|Writing - review & editing	methodology	Performed the experiments	Methodology	YES
6321128	30400382	L.A.	CRediT	methodology|formal analysis|Writing - review & editing	formal analysis	Analyzed the data	Formal analysis	YES
6321128	30400382	L.A.	CRediT	methodology|formal analysis|Writing - review & editing	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
6321128	30400382	M.A.N.C.	CRediT	methodology|formal analysis	methodology	Performed the experiments	Methodology	YES
6321128	30400382	M.A.N.C.	CRediT	methodology|formal analysis	formal analysis	Analyzed the data	Formal analysis	YES
6321128	30400382	M.M.G.	CRediT	methodology|formal analysis|Writing - review & editing	methodology	Performed the experiments	Methodology	YES
6321128	30400382	M.M.G.	CRediT	methodology|formal analysis|Writing - review & editing	formal analysis	Analyzed the data	Formal analysis	YES
6321128	30400382	M.M.G.	CRediT	methodology|formal analysis|Writing - review & editing	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
6321128	30400382	P.R.	CRediT	methodology|formal analysis|supervision	methodology	Performed the experiments	Methodology	YES
6321128	30400382	P.R.	CRediT	methodology|formal analysis|supervision	formal analysis	Analyzed the data	Formal analysis	YES
6321128	30400382	P.R.	CRediT	methodology|formal analysis|supervision	supervision	-	Supervision	YES
6321128	30400382	S.C.C.	CRediT	methodology|formal analysis	methodology	Performed the experiments	Methodology	YES
6321128	30400382	S.C.C.	CRediT	methodology|formal analysis	formal analysis	Analyzed the data	Formal analysis	YES
5857055	29670479	AGA	2	were involved in the design of the study|did the examination and recorded the data	were involved in the design of the study	Conceived and designed the experiments	Methodology	YES
5857055	29670479	AGA	2	were involved in the design of the study|did the examination and recorded the data	did the examination and recorded the data	Performed the experiments	Investigation	YES
5857055	29670479	All authors	2	revised and approved the manuscript before submission	revised and approved the manuscript before submission	Wrote the paper	Writing - Review & Editing	YES
5857055	29670479	EPC	2	were involved in the design of the study|analyzed the data and wrote the manuscript	were involved in the design of the study	Conceived and designed the experiments	Methodology	YES
5857055	29670479	EPC	2	were involved in the design of the study|analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5857055	29670479	FAA	2	were involved in the design of the study|analyzed the data and wrote the manuscript	were involved in the design of the study	Conceived and designed the experiments	Methodology	YES
5857055	29670479	FAA	2	were involved in the design of the study|analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5857055	29670479	SA	2	were involved in the design of the study|analyzed the data and wrote the manuscript	were involved in the design of the study	Conceived and designed the experiments	Methodology	YES
5857055	29670479	SA	2	were involved in the design of the study|analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5857055	29670479	SAA	2	were involved in the design of the study|did the examination and recorded the data	were involved in the design of the study	Conceived and designed the experiments	Methodology	YES
5857055	29670479	SAA	2	were involved in the design of the study|did the examination and recorded the data	did the examination and recorded the data	Performed the experiments	Investigation	YES
5857055	29670479	TAA	2	were involved in the design of the study|did the examination and recorded the data	were involved in the design of the study	Conceived and designed the experiments	Methodology	YES
5857055	29670479	TAA	2	were involved in the design of the study|did the examination and recorded the data	did the examination and recorded the data	Performed the experiments	Investigation	YES
5420596	28533793	AM	PLoS52	conceived and designed the experiments|conducted the experiment, collected, and analyzed the data|proofread and finalized the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5420596	28533793	AM	PLoS52	conceived and designed the experiments|conducted the experiment, collected, and analyzed the data|proofread and finalized the manuscript	conducted the experiment, collected, and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5420596	28533793	AM	PLoS52	conceived and designed the experiments|conducted the experiment, collected, and analyzed the data|proofread and finalized the manuscript	proofread and finalized the manuscript	Wrote the paper	Writing - Review & Editing	YES
5420596	28533793	BRJ	PLoS52	conceived and designed the experiments|proofread and finalized the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5420596	28533793	BRJ	PLoS52	conceived and designed the experiments|proofread and finalized the manuscript	proofread and finalized the manuscript	Wrote the paper	Writing - Review & Editing	YES
5420596	28533793	PS	PLoS52	conceived and designed the experiments|conducted the experiment, collected, and analyzed the data|wrote the draft of the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5420596	28533793	PS	PLoS52	conceived and designed the experiments|conducted the experiment, collected, and analyzed the data|wrote the draft of the manuscript	conducted the experiment, collected, and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5420596	28533793	PS	PLoS52	conceived and designed the experiments|conducted the experiment, collected, and analyzed the data|wrote the draft of the manuscript	wrote the draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
5420596	28533793	YSC	PLoS52	assisted in conducting the experiment, sample collection, and all the analysis	assisted in conducting the experiment, sample collection, and all the analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4397012	25875942	ACO	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397012	25875942	ACO	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4397012	25875942	ACO	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397012	25875942	AKSS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397012	25875942	AKSS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397012	25875942	AKSS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397012	25875942	AKSS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397012	25875942	AKSS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397012	25875942	BSS	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397012	25875942	BSS	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4397012	25875942	BSS	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397012	25875942	CAP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397012	25875942	CAP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397012	25875942	CAP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397012	25875942	CAP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397012	25875942	CAP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397012	25875942	DOCT	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4397012	25875942	DOCT	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397012	25875942	ELR	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397012	25875942	ELR	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4397012	25875942	ELR	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397012	25875942	FOSG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397012	25875942	FOSG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4397012	25875942	FOSG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4397012	25875942	FOSG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397012	25875942	IRP	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397012	25875942	LAMS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4397012	25875942	MCAL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
3033234	21223587	BAE	2	participated in the design of the study, analysis of the data and modification of the manuscript	participated in the design of the study, analysis of the data and modification of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
3033234	21223587	GAE	2	participated in the design of the study, analysis of the data and modification of the manuscript	participated in the design of the study, analysis of the data and modification of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
3033234	21223587	HSS	2	conceived the study, participated in the sequence alignment and drafted the manuscript|prepared and characterized the organic ligand and its complexes	conceived the study, participated in the sequence alignment and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
3033234	21223587	HSS	2	conceived the study, participated in the sequence alignment and drafted the manuscript|prepared and characterized the organic ligand and its complexes	prepared and characterized the organic ligand and its complexes	Performed the experiments	Investigation	YES
3033234	21223587	MAM	2	prepared and characterized the organic ligand and its complexes	prepared and characterized the organic ligand and its complexes	Performed the experiments	Investigation	YES
5871958	29364162	Sotiris Gavriil	7	research plan, data collection, approval of the written manuscript	research plan, data collection, approval of the written manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5871958	29364162	Vaia Draikou	7	research plan, data collection, statistic analyses and manuscript writing	research plan, data collection, statistic analyses and manuscript writing	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5857056	29670482	Anes Joguncic	2	participated in each step of manuscript	participated in each step of manuscript	-	-	NO
5857056	29670482	Fuad Husic	2	participated in each step of manuscript	participated in each step of manuscript	-	-	NO
5857056	29670482	Lutvo Sporisevic	2	participated in each step of manuscript|critically reviewed of the manuscript for important intellectual content	participated in each step of manuscript	-	-	NO
5857056	29670482	Lutvo Sporisevic	2	participated in each step of manuscript|critically reviewed of the manuscript for important intellectual content	critically reviewed of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5857056	29670482	Zaim Jatic	2	participated in each step of manuscript	participated in each step of manuscript	-	-	NO
4983044	27519343	AB	PLoS52	performed the bioinformatic analyses	performed the bioinformatic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4983044	27519343	AM	PLoS52	designed the study|analyzed the data|wrote the manuscript with the help of the other authors	designed the study	Conceived and designed the experiments	Methodology	YES
4983044	27519343	AM	PLoS52	designed the study|analyzed the data|wrote the manuscript with the help of the other authors	analyzed the data	Analyzed the data	Formal analysis	YES
4983044	27519343	AM	PLoS52	designed the study|analyzed the data|wrote the manuscript with the help of the other authors	wrote the manuscript with the help of the other authors	Wrote the paper	Writing - Original Draft	YES
4983044	27519343	CMS	PLoS52	designed the study|wrote the manuscript with the help of the other authors	designed the study	Conceived and designed the experiments	Methodology	YES
4983044	27519343	CMS	PLoS52	designed the study|wrote the manuscript with the help of the other authors	wrote the manuscript with the help of the other authors	Wrote the paper	Writing - Original Draft	YES
4983044	27519343	DN-S	PLoS52	designed the study|performed the experiments	designed the study	Conceived and designed the experiments	Methodology	YES
4983044	27519343	DN-S	PLoS52	designed the study|performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
4983044	27519343	FP	PLoS52	performed the bioinformatic analyses|analyzed the data|wrote the manuscript with the help of the other authors	performed the bioinformatic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4983044	27519343	FP	PLoS52	performed the bioinformatic analyses|analyzed the data|wrote the manuscript with the help of the other authors	analyzed the data	Analyzed the data	Formal analysis	YES
4983044	27519343	FP	PLoS52	performed the bioinformatic analyses|analyzed the data|wrote the manuscript with the help of the other authors	wrote the manuscript with the help of the other authors	Wrote the paper	Writing - Original Draft	YES
4983044	27519343	JB	PLoS52	analyzed the data|wrote the manuscript with the help of the other authors	analyzed the data	Analyzed the data	Formal analysis	YES
4983044	27519343	JB	PLoS52	analyzed the data|wrote the manuscript with the help of the other authors	wrote the manuscript with the help of the other authors	Wrote the paper	Writing - Original Draft	YES
4983044	27519343	JS	PLoS52	designed the study|analyzed the data|wrote the manuscript with the help of the other authors	designed the study	Conceived and designed the experiments	Methodology	YES
4983044	27519343	JS	PLoS52	designed the study|analyzed the data|wrote the manuscript with the help of the other authors	analyzed the data	Analyzed the data	Formal analysis	YES
4983044	27519343	JS	PLoS52	designed the study|analyzed the data|wrote the manuscript with the help of the other authors	wrote the manuscript with the help of the other authors	Wrote the paper	Writing - Original Draft	YES
4983044	27519343	KAH	PLoS52	designed the study|performed the experiments	designed the study	Conceived and designed the experiments	Methodology	YES
4983044	27519343	KAH	PLoS52	designed the study|performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
4983044	27519343	KUF	PLoS52	performed the bioinformatic analyses	performed the bioinformatic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4983044	27519343	MH	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
4983044	27519343	RH	PLoS52	performed the bioinformatic analyses	performed the bioinformatic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3124674	21747822	B. Hallgrimsson	2	participated in the writing of the paper and in the design of the validation|analyzed the results|directed the research	participated in the writing of the paper and in the design of the validation	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Validation|Writing - Original Draft	YES
3124674	21747822	B. Hallgrimsson	2	participated in the writing of the paper and in the design of the validation|analyzed the results|directed the research	analyzed the results	Analyzed the data	Formal analysis	YES
3124674	21747822	B. Hallgrimsson	2	participated in the writing of the paper and in the design of the validation|analyzed the results|directed the research	directed the research	-	Supervision	YES
3124674	21747822	C. W. Sensen	2	participated in the writing of the paper and in the design of the validation|directed the research	participated in the writing of the paper and in the design of the validation	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Validation|Writing - Original Draft	YES
3124674	21747822	C. W. Sensen	2	participated in the writing of the paper and in the design of the validation|directed the research	directed the research	-	Supervision	YES
3124674	21747822	E. J. Schmidt	2	participated in the writing of the paper and in the design of the validation|performed the manual counts	participated in the writing of the paper and in the design of the validation	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Validation|Writing - Original Draft	YES
3124674	21747822	E. J. Schmidt	2	participated in the writing of the paper and in the design of the validation|performed the manual counts	performed the manual counts	Performed the experiments	Investigation	YES
3124674	21747822	H. A. Jamniczky	2	participated in the writing of the paper and in the design of the validation	participated in the writing of the paper and in the design of the validation	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Validation|Writing - Original Draft	YES
3124674	21747822	J. C. Boughner	2	participated in the writing of the paper and in the design of the validation|performed the manual counts	participated in the writing of the paper and in the design of the validation	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Validation|Writing - Original Draft	YES
3124674	21747822	J. C. Boughner	2	participated in the writing of the paper and in the design of the validation|performed the manual counts	performed the manual counts	Performed the experiments	Investigation	YES
3124674	21747822	J. Soh	2	participated in the writing of the paper and in the design of the validation	participated in the writing of the paper and in the design of the validation	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Validation|Writing - Original Draft	YES
3124674	21747822	M. Xiao	2	participated in the writing of the paper and in the design of the validation	participated in the writing of the paper and in the design of the validation	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Validation|Writing - Original Draft	YES
3124674	21747822	O. E. Meruvia-Pastor	2	wrote the method description and produced the counts using the automated software tools|analyzed the results	wrote the method description and produced the counts using the automated software tools	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Software|Writing - Original Draft	YES
3124674	21747822	O. E. Meruvia-Pastor	2	wrote the method description and produced the counts using the automated software tools|analyzed the results	analyzed the results	Analyzed the data	Formal analysis	YES
3033235	21232132	DN	2	designed the study, analyzed data, and drafted the manuscript	designed the study, analyzed data, and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3033235	21232132	NB	2	designed the study, analyzed data, and drafted the manuscript	designed the study, analyzed data, and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4397013	25875000	AV	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397013	25875000	AV	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397013	25875000	EG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397013	25875000	EG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397013	25875000	EG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397013	25875000	EG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397013	25875000	EG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397013	25875000	EP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397013	25875000	EP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397013	25875000	ER	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397013	25875000	ER	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397013	25875000	ER	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397013	25875000	ER	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397013	25875000	ER	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397013	25875000	JB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4397013	25875000	LS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397013	25875000	LS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397013	25875000	LS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397013	25875000	LS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397013	25875000	YB	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4397013	25875000	YZ	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5421193	28533784	GN	2	designed the experiments and drafted the manuscript|thoroughly revised the manuscript and finalized the manuscript	designed the experiments and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5421193	28533784	GN	2	designed the experiments and drafted the manuscript|thoroughly revised the manuscript and finalized the manuscript	thoroughly revised the manuscript and finalized the manuscript	Wrote the paper	Writing - Review & Editing	YES
5421193	28533784	JL	2	participated in the coordination of the experiments	participated in the coordination of the experiments	Performed the experiments	Investigation|Project administration	YES
5421193	28533784	JM	2	participated in the coordination of the experiments	participated in the coordination of the experiments	Performed the experiments	Investigation|Project administration	YES
5421193	28533784	JZ	2	thoroughly revised the manuscript and finalized the manuscript	thoroughly revised the manuscript and finalized the manuscript	Wrote the paper	Writing - Review & Editing	YES
5421193	28533784	MB	2	thoroughly revised the manuscript and finalized the manuscript	thoroughly revised the manuscript and finalized the manuscript	Wrote the paper	Writing - Review & Editing	YES
5421193	28533784	RY	2	participated in the coordination of the experiments	participated in the coordination of the experiments	Performed the experiments	Investigation|Project administration	YES
5421193	28533784	UD	2	participated in the coordination of the experiments	participated in the coordination of the experiments	Performed the experiments	Investigation|Project administration	YES
5421193	28533784	YS	2	participated in the coordination of the experiments	participated in the coordination of the experiments	Performed the experiments	Investigation|Project administration	YES
5421193	28533784	YZ	2	participated in the coordination of the experiments	participated in the coordination of the experiments	Performed the experiments	Investigation|Project administration	YES
5421193	28533784	ZW	2	designed the experiments and drafted the manuscript	designed the experiments and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5871959	29370077	Ali I. Al-Gareeb	PLoS52	conceived and designed the experiments|analyzed the data	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5871959	29370077	Ali I. Al-Gareeb	PLoS52	conceived and designed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5871959	29370077	Ali K. Al-Buhadilly	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5871959	29370077	Ali K. Al-Buhadilly	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5871959	29370077	all authors	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3038885	21299842	AGP	2	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3038885	21299842	DLM	2	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3038885	21299842	JM	2	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3038885	21299842	LH	2	performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
3038885	21299842	MJP	2	carried out the chemical assays	carried out the chemical assays	Performed the experiments	Investigation	YES
3038885	21299842	SJC	2	performed the data analysis and drafted the manuscript	performed the data analysis and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3038885	21299842	WJH	2	carried out the chemical assays	carried out the chemical assays	Performed the experiments	Investigation	YES
5857057	29670472	E.H.	2	was made final proof reading of the manuscript before printing	was made final proof reading of the manuscript before printing	-	-	NO
4983049	27519264	GWC	2	analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4983049	27519264	MAH	2	analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4983049	27519264	RLB	2	analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4983049	27519264	YF	2	analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5421195	28533795	EP	PLoS52	designed the experiments|performed the experiments|analyzed the results|wrote and approved the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5421195	28533795	EP	PLoS52	designed the experiments|performed the experiments|analyzed the results|wrote and approved the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5421195	28533795	EP	PLoS52	designed the experiments|performed the experiments|analyzed the results|wrote and approved the manuscript	analyzed the results	Analyzed the data	Formal analysis	YES
5421195	28533795	EP	PLoS52	designed the experiments|performed the experiments|analyzed the results|wrote and approved the manuscript	wrote and approved the manuscript	Wrote the paper	Writing - Original Draft	YES
5421195	28533795	KK	PLoS52	designed the experiments|performed the experiments|wrote and approved the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5421195	28533795	KK	PLoS52	designed the experiments|performed the experiments|wrote and approved the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5421195	28533795	KK	PLoS52	designed the experiments|performed the experiments|wrote and approved the manuscript	wrote and approved the manuscript	Wrote the paper	Writing - Original Draft	YES
5421195	28533795	MF	PLoS52	designed the experiments|performed the experiments|analyzed the results|wrote and approved the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5421195	28533795	MF	PLoS52	designed the experiments|performed the experiments|analyzed the results|wrote and approved the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5421195	28533795	MF	PLoS52	designed the experiments|performed the experiments|analyzed the results|wrote and approved the manuscript	analyzed the results	Analyzed the data	Formal analysis	YES
5421195	28533795	MF	PLoS52	designed the experiments|performed the experiments|analyzed the results|wrote and approved the manuscript	wrote and approved the manuscript	Wrote the paper	Writing - Original Draft	YES
5421195	28533795	SN	PLoS52	designed the experiments|wrote and approved the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5421195	28533795	SN	PLoS52	designed the experiments|wrote and approved the manuscript	wrote and approved the manuscript	Wrote the paper	Writing - Original Draft	YES
5421195	28533795	TG	PLoS52	designed the experiments|analyzed the results|wrote and approved the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5421195	28533795	TG	PLoS52	designed the experiments|analyzed the results|wrote and approved the manuscript	analyzed the results	Analyzed the data	Formal analysis	YES
5421195	28533795	TG	PLoS52	designed the experiments|analyzed the results|wrote and approved the manuscript	wrote and approved the manuscript	Wrote the paper	Writing - Original Draft	YES
3041729	21306655	LJM	2	has been involved in revising for important intellectual content and structure of manuscript	has been involved in revising for important intellectual content and structure of manuscript	Wrote the paper	Writing - Review & Editing	YES
3041729	21306655	PR	2	has made substantial contributions to conception and design, analysis and interpretation of data, revises for important intellectual content and coordination and has given final approval of the version to be published	has made substantial contributions to conception and design, analysis and interpretation of data, revises for important intellectual content and coordination and has given final approval of the version to be published	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Project administration|Resources|Writing - Review & Editing	YES
3041729	21306655	PS	2	have given final approval of the version to be published	have given final approval of the version to be published	-	-	NO
3041729	21306655	SW	2	have given final approval of the version to be published	have given final approval of the version to be published	-	-	NO
3041729	21306655	WT	2	carried out the study design, film preparation, testing, performed the statistical analysis and drafted the manuscript	carried out the study design, film preparation, testing, performed the statistical analysis and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5871960	29385762	Aditya Mathur	2	helped in data management|revised the paper critically for substantial intellectual content	helped in data management	Analyzed the data	Data curation	YES
5871960	29385762	Aditya Mathur	2	helped in data management|revised the paper critically for substantial intellectual content	revised the paper critically for substantial intellectual content	Wrote the paper	Writing - Review & Editing	YES
5871960	29385762	Ashish Pathak	2	participated in the conception and design of the study|collected the data|performed the statistical analysis|drafted the manuscript|revised the paper critically for substantial intellectual content	participated in the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5871960	29385762	Ashish Pathak	2	participated in the conception and design of the study|collected the data|performed the statistical analysis|drafted the manuscript|revised the paper critically for substantial intellectual content	collected the data	Performed the experiments	Investigation	YES
5871960	29385762	Ashish Pathak	2	participated in the conception and design of the study|collected the data|performed the statistical analysis|drafted the manuscript|revised the paper critically for substantial intellectual content	performed the statistical analysis	Analyzed the data	Formal analysis	YES
5871960	29385762	Ashish Pathak	2	participated in the conception and design of the study|collected the data|performed the statistical analysis|drafted the manuscript|revised the paper critically for substantial intellectual content	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5871960	29385762	Ashish Pathak	2	participated in the conception and design of the study|collected the data|performed the statistical analysis|drafted the manuscript|revised the paper critically for substantial intellectual content	revised the paper critically for substantial intellectual content	Wrote the paper	Writing - Review & Editing	YES
5871960	29385762	Cecilia Stalsby Lundborg	2	participated in the conception and design of the study|revised the paper critically for substantial intellectual content	participated in the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5871960	29385762	Cecilia Stalsby Lundborg	2	participated in the conception and design of the study|revised the paper critically for substantial intellectual content	revised the paper critically for substantial intellectual content	Wrote the paper	Writing - Review & Editing	YES
5871960	29385762	Mamta Dhaneria	2	participated in the conception and design of the study|collected the data|revised the paper critically for substantial intellectual content	participated in the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5871960	29385762	Mamta Dhaneria	2	participated in the conception and design of the study|collected the data|revised the paper critically for substantial intellectual content	collected the data	Performed the experiments	Investigation	YES
5871960	29385762	Mamta Dhaneria	2	participated in the conception and design of the study|collected the data|revised the paper critically for substantial intellectual content	revised the paper critically for substantial intellectual content	Wrote the paper	Writing - Review & Editing	YES
5871960	29385762	Poonam Singh	2	participated in the conception and design of the study|collected the data|revised the paper critically for substantial intellectual content	participated in the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5871960	29385762	Poonam Singh	2	participated in the conception and design of the study|collected the data|revised the paper critically for substantial intellectual content	collected the data	Performed the experiments	Investigation	YES
5871960	29385762	Poonam Singh	2	participated in the conception and design of the study|collected the data|revised the paper critically for substantial intellectual content	revised the paper critically for substantial intellectual content	Wrote the paper	Writing - Review & Editing	YES
5871960	29385762	Sachin Jain	2	participated in the conception and design of the study|collected the data|performed the statistical analysis|revised the paper critically for substantial intellectual content	participated in the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5871960	29385762	Sachin Jain	2	participated in the conception and design of the study|collected the data|performed the statistical analysis|revised the paper critically for substantial intellectual content	collected the data	Performed the experiments	Investigation	YES
5871960	29385762	Sachin Jain	2	participated in the conception and design of the study|collected the data|performed the statistical analysis|revised the paper critically for substantial intellectual content	performed the statistical analysis	Analyzed the data	Formal analysis	YES
5871960	29385762	Sachin Jain	2	participated in the conception and design of the study|collected the data|performed the statistical analysis|revised the paper critically for substantial intellectual content	revised the paper critically for substantial intellectual content	Wrote the paper	Writing - Review & Editing	YES
5857058	29670471	Aggeliki Koukouzeli	2	provided support for data selection	provided support for data selection	Contributed reagents/materials/analysis tools	Resources	YES
5857058	29670471	All authors	2	contributed substantially to drafts and revisions of the manuscript|also approved the current revised version	contributed substantially to drafts and revisions of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5857058	29670471	All authors	2	contributed substantially to drafts and revisions of the manuscript|also approved the current revised version	also approved the current revised version	Wrote the paper	Writing - Review & Editing	YES
5857058	29670471	Georgia Fouka	2	designed and performed the research, analyzed the data, and wrote the manuscript	designed and performed the research, analyzed the data, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5857058	29670471	Georgia Gerogianni	2	designed and performed the research, analyzed the data, and wrote the manuscript	designed and performed the research, analyzed the data, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5857058	29670471	Ioannis Koutelekos	2	designed and performed the research, analyzed the data, and wrote the manuscript	designed and performed the research, analyzed the data, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5857058	29670471	Maria Koutsaki	2	provided support for data selection	provided support for data selection	Contributed reagents/materials/analysis tools	Resources	YES
5857058	29670471	Maria Polikandrioti	2	designed and performed the research, analyzed the data, and wrote the manuscript	designed and performed the research, analyzed the data, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5857058	29670471	Styliani Koutsaki	2	designed and performed the research, analyzed the data, and wrote the manuscript	designed and performed the research, analyzed the data, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4397014	25874800	MR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397014	25874800	MR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397014	25874800	MR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397014	25874800	MR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397014	25874800	MR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6321141	30463329	C.W.	CRediT	Funding acquisition	Funding acquisition	-	Funding acquisition	YES
6321141	30463329	J.L.	CRediT	Writing-review & editing|Visualization	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6321141	30463329	J.L.	CRediT	Writing-review & editing|Visualization	Visualization	Analyzed the data	Visualization	YES
6321141	30463329	W.C.	CRediT	Software	Software	Contributed reagents/materials/analysis tools	Software	YES
6321141	30463329	X.P.	CRediT	Resources|Supervision|Funding acquisition	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6321141	30463329	X.P.	CRediT	Resources|Supervision|Funding acquisition	Supervision	-	Supervision	YES
6321141	30463329	X.P.	CRediT	Resources|Supervision|Funding acquisition	Funding acquisition	-	Funding acquisition	YES
6321141	30463329	X.X.	CRediT	Data curation	Data curation	Analyzed the data	Data curation	YES
6321141	30463329	X.Z.	CRediT	Methodology|Software|Investigation	Methodology	Performed the experiments	Methodology	YES
6321141	30463329	X.Z.	CRediT	Methodology|Software|Investigation	Software	Contributed reagents/materials/analysis tools	Software	YES
6321141	30463329	X.Z.	CRediT	Methodology|Software|Investigation	Investigation	Performed the experiments	Investigation	YES
6321141	30463329	Y.H.	CRediT	Validation|Writing-review & editing|Project administration	Validation	Performed the experiments	Validation	YES
6321141	30463329	Y.H.	CRediT	Validation|Writing-review & editing|Project administration	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6321141	30463329	Y.H.	CRediT	Validation|Writing-review & editing|Project administration	Project administration	-	Project administration	YES
6321141	30463329	Y.Y.	CRediT	Conceptualization|Validation|Formal analysis|Writing-original draft preparation|Visualization	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6321141	30463329	Y.Y.	CRediT	Conceptualization|Validation|Formal analysis|Writing-original draft preparation|Visualization	Validation	Performed the experiments	Validation	YES
6321141	30463329	Y.Y.	CRediT	Conceptualization|Validation|Formal analysis|Writing-original draft preparation|Visualization	Formal analysis	Analyzed the data	Formal analysis	YES
6321141	30463329	Y.Y.	CRediT	Conceptualization|Validation|Formal analysis|Writing-original draft preparation|Visualization	Writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
6321141	30463329	Y.Y.	CRediT	Conceptualization|Validation|Formal analysis|Writing-original draft preparation|Visualization	Visualization	Analyzed the data	Visualization	YES
6321141	30463329	Z.H.	CRediT	Conceptualization|Validation|Writing-review & editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6321141	30463329	Z.H.	CRediT	Conceptualization|Validation|Writing-review & editing	Validation	Performed the experiments	Validation	YES
6321141	30463329	Z.H.	CRediT	Conceptualization|Validation|Writing-review & editing	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
5421198	28533794	HG	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5421198	28533794	HW	2	complemented the experiment	complemented the experiment	-	-	NO
5421198	28533794	HX	2	complemented the experiment	complemented the experiment	-	-	NO
5421198	28533794	JF	2	performed most of the experiments	performed most of the experiments	Performed the experiments	Investigation	YES
5421198	28533794	JG	2	performed most of the experiments	performed most of the experiments	Performed the experiments	Investigation	YES
5421198	28533794	JL	2	performed most of the experiments	performed most of the experiments	Performed the experiments	Investigation	YES
5421198	28533794	LT	2	complemented the experiment	complemented the experiment	-	-	NO
5421198	28533794	LW	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5421198	28533794	MY	2	conceived the project and supervised the experiments|revised the manuscript	conceived the project and supervised the experiments	Conceived and designed the experiments	Conceptualization|Supervision	YES
5421198	28533794	MY	2	conceived the project and supervised the experiments|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5421198	28533794	RS	2	measured al content and constructional suggestions to the research	measured al content and constructional suggestions to the research	Performed the experiments	Investigation	YES
5421198	28533794	XL	2	wrote the article and analyzed the data|performed most of the experiments	wrote the article and analyzed the data	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5421198	28533794	XL	2	wrote the article and analyzed the data|performed most of the experiments	performed most of the experiments	Performed the experiments	Investigation	YES
5421198	28533794	YF	2	complemented the experiment	complemented the experiment	-	-	NO
5421198	28533794	YH	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5421198	28533794	YL	2	complemented the experiment	complemented the experiment	-	-	NO
3042368	21284885	JO	2	made critical review of the manuscript, approved submission of article for publication	made critical review of the manuscript, approved submission of article for publication	Wrote the paper	Writing - Review & Editing	YES
3042368	21284885	NS	2	made critical review of the manuscript, approved submission of article for publication	made critical review of the manuscript, approved submission of article for publication	Wrote the paper	Writing - Review & Editing	YES
3042368	21284885	RL	2	performed all practical experiments and prepared article manuscript	performed all practical experiments and prepared article manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4986183	27527502	AC	2	performed the experiments and genome sequencing preparations	performed the experiments and genome sequencing preparations	Performed the experiments	Investigation	YES
4986183	27527502	All authors	2	read, edited and approved the final manuscript	read, edited and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4986183	27527502	JDZ	2	performed annotation of the genomic sequences	performed annotation of the genomic sequences	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
4986183	27527502	JML	2	conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4986183	27527502	XLH	2	conceived the study|created its design, performed bioinformatics analyses, and drafted the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4986183	27527502	XLH	2	conceived the study|created its design, performed bioinformatics analyses, and drafted the manuscript	created its design, performed bioinformatics analyses, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4986183	27527502	ZXL	2	conceived the study|performed the experiments and genome sequencing preparations	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4986183	27527502	ZXL	2	conceived the study|performed the experiments and genome sequencing preparations	performed the experiments and genome sequencing preparations	Performed the experiments	Investigation	YES
5871961	29419750	G.A.	2	manuscript writing	manuscript writing	Wrote the paper	Writing - Original Draft	YES
5871961	29419750	I.N.	2	radiographs evaluation	radiographs evaluation	-	-	NO
6029895	30061804	All authors	2	are included in all pahases of preparation of this article	are included in all pahases of preparation of this article	-	-	NO
4397015	25875100	IS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4397015	25875100	IS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4397015	25875100	LAL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397015	25875100	LAL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397015	25875100	LAL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397015	25875100	LAL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397015	25875100	LAL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397015	25875100	PPL	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397015	25875100	TPP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397015	25875100	TPP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397015	25875100	TPP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397015	25875100	TPP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397015	25875100	TPP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5422474	28536590	AM	2	designed the study|developed dcs -ilp markers|drafted sections of the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5422474	28536590	AM	2	designed the study|developed dcs -ilp markers|drafted sections of the manuscript	developed dcs -ilp markers	-	-	NO
5422474	28536590	AM	2	designed the study|developed dcs -ilp markers|drafted sections of the manuscript	drafted sections of the manuscript	Wrote the paper	Writing - Original Draft	YES
5422474	28536590	All authors	2	read, reviewed and approved the manuscript	read, reviewed and approved the manuscript	Wrote the paper	Writing - Review & Editing	YES
5422474	28536590	DG	2	designed the study|drafted sections of the manuscript|prepared the final version of the paper	designed the study	Conceived and designed the experiments	Methodology	YES
5422474	28536590	DG	2	designed the study|drafted sections of the manuscript|prepared the final version of the paper	drafted sections of the manuscript	Wrote the paper	Writing - Original Draft	YES
5422474	28536590	DG	2	designed the study|drafted sections of the manuscript|prepared the final version of the paper	prepared the final version of the paper	Wrote the paper	Writing - Original Draft	YES
5422474	28536590	GM	2	developed dcs -ilp markers|drafted sections of the manuscript	developed dcs -ilp markers	-	-	NO
5422474	28536590	GM	2	developed dcs -ilp markers|drafted sections of the manuscript	drafted sections of the manuscript	Wrote the paper	Writing - Original Draft	YES
5422474	28536590	KS	2	designed the study|developed dcs -ilp markers|performed the validation of candidate dcs -ilp markers and the assessment of genetic diversity|drafted sections of the manuscript|prepared the final version of the paper	designed the study	Conceived and designed the experiments	Methodology	YES
5422474	28536590	KS	2	designed the study|developed dcs -ilp markers|performed the validation of candidate dcs -ilp markers and the assessment of genetic diversity|drafted sections of the manuscript|prepared the final version of the paper	developed dcs -ilp markers	-	-	NO
5422474	28536590	KS	2	designed the study|developed dcs -ilp markers|performed the validation of candidate dcs -ilp markers and the assessment of genetic diversity|drafted sections of the manuscript|prepared the final version of the paper	performed the validation of candidate dcs -ilp markers and the assessment of genetic diversity	Performed the experiments	Investigation|Validation	YES
5422474	28536590	KS	2	designed the study|developed dcs -ilp markers|performed the validation of candidate dcs -ilp markers and the assessment of genetic diversity|drafted sections of the manuscript|prepared the final version of the paper	drafted sections of the manuscript	Wrote the paper	Writing - Original Draft	YES
5422474	28536590	KS	2	designed the study|developed dcs -ilp markers|performed the validation of candidate dcs -ilp markers and the assessment of genetic diversity|drafted sections of the manuscript|prepared the final version of the paper	prepared the final version of the paper	Wrote the paper	Writing - Original Draft	YES
4986186	27527070	AT	PLoS5	Performed computational analysis|Analyzed the data and provide input to the manuscript	Performed computational analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4986186	27527070	AT	PLoS5	Performed computational analysis|Analyzed the data and provide input to the manuscript	Analyzed the data and provide input to the manuscript	Analyzed the data	Formal analysis	YES
4986186	27527070	DMH	PLoS5	Performed computational analysis|Analyzed the data and provide input to the manuscript	Performed computational analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4986186	27527070	DMH	PLoS5	Performed computational analysis|Analyzed the data and provide input to the manuscript	Analyzed the data and provide input to the manuscript	Analyzed the data	Formal analysis	YES
4986186	27527070	KBZ	PLoS5	Managed study participants consent and sample collection|Analyzed the data and provide input to the manuscript	Managed study participants consent and sample collection	Performed the experiments	Investigation|Project administration	YES
4986186	27527070	KBZ	PLoS5	Managed study participants consent and sample collection|Analyzed the data and provide input to the manuscript	Analyzed the data and provide input to the manuscript	Analyzed the data	Formal analysis	YES
4986186	27527070	KEN	PLoS5	Participated in experiments|Analyzed the data and provide input to the manuscript|Wrote the paper|Conceived, designed, and supervised	Participated in experiments	Performed the experiments	Investigation	YES
4986186	27527070	KEN	PLoS5	Participated in experiments|Analyzed the data and provide input to the manuscript|Wrote the paper|Conceived, designed, and supervised	Analyzed the data and provide input to the manuscript	Analyzed the data	Formal analysis	YES
4986186	27527070	KEN	PLoS5	Participated in experiments|Analyzed the data and provide input to the manuscript|Wrote the paper|Conceived, designed, and supervised	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4986186	27527070	KEN	PLoS5	Participated in experiments|Analyzed the data and provide input to the manuscript|Wrote the paper|Conceived, designed, and supervised	Conceived, designed, and supervised	Conceived and designed the experiments	Conceptualization|Supervision	YES
4986186	27527070	KJM	PLoS5	Participated in experiments	Participated in experiments	Performed the experiments	Investigation	YES
4986186	27527070	LS	PLoS5	Managed study participants consent and sample collection|Analyzed the data and provide input to the manuscript|Conceived, designed, and supervised	Managed study participants consent and sample collection	Performed the experiments	Investigation|Project administration	YES
4986186	27527070	LS	PLoS5	Managed study participants consent and sample collection|Analyzed the data and provide input to the manuscript|Conceived, designed, and supervised	Analyzed the data and provide input to the manuscript	Analyzed the data	Formal analysis	YES
4986186	27527070	LS	PLoS5	Managed study participants consent and sample collection|Analyzed the data and provide input to the manuscript|Conceived, designed, and supervised	Conceived, designed, and supervised	Conceived and designed the experiments	Conceptualization|Supervision	YES
4986186	27527070	MT	PLoS5	Participated in experiments|Analyzed the data and provide input to the manuscript	Participated in experiments	Performed the experiments	Investigation	YES
4986186	27527070	MT	PLoS5	Participated in experiments|Analyzed the data and provide input to the manuscript	Analyzed the data and provide input to the manuscript	Analyzed the data	Formal analysis	YES
4986186	27527070	RP	PLoS5	Analyzed the data and provide input to the manuscript|Wrote the paper	Analyzed the data and provide input to the manuscript	Analyzed the data	Formal analysis	YES
4986186	27527070	RP	PLoS5	Analyzed the data and provide input to the manuscript|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4986186	27527070	SKH	PLoS5	Analyzed the data and provide input to the manuscript	Analyzed the data and provide input to the manuscript	Analyzed the data	Formal analysis	YES
4986186	27527070	SRV	PLoS5	Analyzed the data and provide input to the manuscript	Analyzed the data and provide input to the manuscript	Analyzed the data	Formal analysis	YES
4986186	27527070	SVR	PLoS5	Participated in experiments|Wrote the paper	Participated in experiments	Performed the experiments	Investigation	YES
4986186	27527070	SVR	PLoS5	Participated in experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4986186	27527070	SY	PLoS5	Performed computational analysis|Analyzed the data and provide input to the manuscript|Wrote the paper	Performed computational analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4986186	27527070	SY	PLoS5	Performed computational analysis|Analyzed the data and provide input to the manuscript|Wrote the paper	Analyzed the data and provide input to the manuscript	Analyzed the data	Formal analysis	YES
4986186	27527070	SY	PLoS5	Performed computational analysis|Analyzed the data and provide input to the manuscript|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3050788	21329529	DK	2	carried out the synthetic experiments, purification of compounds, literature survey, spectroscopic analyses and drafted the manuscript	carried out the synthetic experiments, purification of compounds, literature survey, spectroscopic analyses and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3050788	21329529	JCS	2	arranged the work and modified the manuscript	arranged the work and modified the manuscript	Wrote the paper	Writing - Review & Editing	YES
6321143	30257514	A.A.I.	2	helped revised the manuscript, provided feedback, and valuable suggestions	helped revised the manuscript, provided feedback, and valuable suggestions	Wrote the paper	Writing - Review & Editing	YES
6321143	30257514	A.S.T.	2	conducted the literature search and prepared the tables|prepared the final manuscript and are responsible for the overall quality and content of the manuscript as the leads and corresponding authors	conducted the literature search and prepared the tables	Performed the experiments	Formal analysis|Investigation	YES
6321143	30257514	A.S.T.	2	conducted the literature search and prepared the tables|prepared the final manuscript and are responsible for the overall quality and content of the manuscript as the leads and corresponding authors	prepared the final manuscript and are responsible for the overall quality and content of the manuscript as the leads and corresponding authors	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6321143	30257514	M.V.Z.	2	helped revised the manuscript, provided feedback, and valuable suggestions|prepared the final manuscript and are responsible for the overall quality and content of the manuscript as the leads and corresponding authors	helped revised the manuscript, provided feedback, and valuable suggestions	Wrote the paper	Writing - Review & Editing	YES
6321143	30257514	M.V.Z.	2	helped revised the manuscript, provided feedback, and valuable suggestions|prepared the final manuscript and are responsible for the overall quality and content of the manuscript as the leads and corresponding authors	prepared the final manuscript and are responsible for the overall quality and content of the manuscript as the leads and corresponding authors	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6321143	30257514	all authors	2	have contributed materially and intellectually through several joint papers on the preparation of porous drug carriers, which helped to shape the intellectual basis of the current review paper	have contributed materially and intellectually through several joint papers on the preparation of porous drug carriers, which helped to shape the intellectual basis of the current review paper	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Review & Editing	YES
4986197	27526849	SN	2	designed the study, implemented the analysis and wrote the manuscript	designed the study, implemented the analysis and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5422509	28536596	DW	2	actively participated in the preparation of this manuscript especially through assisting with statistical analysis of the data and review of the draft manuscript	actively participated in the preparation of this manuscript especially through assisting with statistical analysis of the data and review of the draft manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5422509	28536596	FM	2	is the primary author of this manuscript|was in charge of the conduct of the experiments under both cold temperature stress and normal temperature conditions in both test seasons as well as analysis of the data and drafting of the manuscript	is the primary author of this manuscript	Wrote the paper	Writing - Original Draft	YES
5422509	28536596	FM	2	is the primary author of this manuscript|was in charge of the conduct of the experiments under both cold temperature stress and normal temperature conditions in both test seasons as well as analysis of the data and drafting of the manuscript	was in charge of the conduct of the experiments under both cold temperature stress and normal temperature conditions in both test seasons as well as analysis of the data and drafting of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5422509	28536596	TT	2	is the corresponding author on this manuscript|is the pi of the project under which this study was carried out and was responsible for supervising the conduct of the experiment, analysis of the data and for finalizing the review and submission of the manuscript	is the corresponding author on this manuscript	-	-	NO
5422509	28536596	TT	2	is the corresponding author on this manuscript|is the pi of the project under which this study was carried out and was responsible for supervising the conduct of the experiment, analysis of the data and for finalizing the review and submission of the manuscript	is the pi of the project under which this study was carried out and was responsible for supervising the conduct of the experiment, analysis of the data and for finalizing the review and submission of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Supervision|Writing - Review & Editing	YES
4397016	25875838	DNK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397016	25875838	DNK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397016	25875838	DNK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397016	25875838	DNK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397016	25875838	JKA-Y	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397016	25875838	JKA-Y	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397016	25875838	JKA-Y	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397016	25875838	JKA-Y	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397016	25875838	JS	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397016	25875838	MJ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4397016	25875838	NJH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4397016	25875838	PJG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397016	25875838	PJG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397016	25875838	PJG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397016	25875838	PJG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397016	25875838	PWA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397016	25875838	PWA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397016	25875838	PWA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397016	25875838	SS	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4397016	25875838	SVD	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4397016	25875838	TE	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397016	25875838	TE	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397016	25875838	TE	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5871963	29462898	A.L.	2	conceived the research question, designed the study, participated in analysing data, writing and critically revising all the versions of the manuscript	conceived the research question, designed the study, participated in analysing data, writing and critically revising all the versions of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5871963	29462898	All Authors	2	approved the final version of the article, including the authorship list	approved the final version of the article, including the authorship list	-	-	NO
5871963	29462898	D.R.	2	gathered the data and revised the paper	gathered the data and revised the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5871963	29462898	E.B.	2	gathered the data	gathered the data	Performed the experiments	Investigation	YES
5871963	29462898	F.N.	2	analysed the data and wrote the first draft of the manuscript	analysed the data and wrote the first draft of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5871963	29462898	S.B.	2	gathered the data and revised the paper	gathered the data and revised the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5871963	29462898	S.L.	2	gathered the data and revised the paper	gathered the data and revised the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5871963	29462898	V.G.	2	gathered the data	gathered the data	Performed the experiments	Investigation	YES
5871963	29462898	V.S.	2	gathered the data	gathered the data	Performed the experiments	Investigation	YES
4385656	25874208	H. Vivanco-Cid	PLoS52	conceived and designed the paper|wrote the paper	conceived and designed the paper	Conceived and designed the experiments	Conceptualization	YES
4385656	25874208	H. Vivanco-Cid	PLoS52	conceived and designed the paper|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4385656	25874208	K. G. Hernandez-Flores	PLoS52	conceived and designed the paper|wrote the paper	conceived and designed the paper	Conceived and designed the experiments	Conceptualization	YES
4385656	25874208	K. G. Hernandez-Flores	PLoS52	conceived and designed the paper|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3060835	21371324	DJP	2	was in charge of some plasma antioxidant status determinations	was in charge of some plasma antioxidant status determinations	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3060835	21371324	JCG	2	conceived of the study, participated in its design and coordination, performed data analysis and contributed to the drafting of the manuscript	conceived of the study, participated in its design and coordination, performed data analysis and contributed to the drafting of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Project administration|Writing - Original Draft	YES
3060835	21371324	JJO	2	was involved in the products physicochemical assessment, the chromatographic determinations and drafting of the manuscript	was involved in the products physicochemical assessment, the chromatographic determinations and drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
3060835	21371324	LMP	2	conducted statistical analysis and drafting of the manuscript	conducted statistical analysis and drafting of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3060835	21371324	RES	2	was involved in analytical method development and data collection	was involved in analytical method development and data collection	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
3060835	21371324	SRM	2	was the subjects coordinator who conducted volunteer interviews, set up database used to collect and organize data and drafting of the manuscript	was the subjects coordinator who conducted volunteer interviews, set up database used to collect and organize data and drafting of the manuscript	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Methodology|Project administration|Software|Writing - Original Draft	YES
4397017	25874627	CCS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397017	25874627	CMT	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397017	25874627	CMT	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397017	25874627	CMT	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397017	25874627	HCP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Provided animals and facilities	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397017	25874627	HCP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Provided animals and facilities	Performed the experiments	Performed the experiments	Investigation	YES
4397017	25874627	HCP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Provided animals and facilities	Analyzed the data	Analyzed the data	Formal analysis	YES
4397017	25874627	HCP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Provided animals and facilities	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397017	25874627	HCP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Provided animals and facilities	Provided animals and facilities	-	-	NO
4397017	25874627	JPL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397017	25874627	SK	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397017	25874627	SLP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Provided animals and facilities	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397017	25874627	SLP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Provided animals and facilities	Performed the experiments	Performed the experiments	Investigation	YES
4397017	25874627	SLP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Provided animals and facilities	Analyzed the data	Analyzed the data	Formal analysis	YES
4397017	25874627	SLP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Provided animals and facilities	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397017	25874627	SLP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Provided animals and facilities	Provided animals and facilities	-	-	NO
6029905	30061796	A.D.	2	gave substantial contributions to the conception, design, acquisition, analysis, and interpretation of data, revised it critically and gave final approval of the version to be published	gave substantial contributions to the conception, design, acquisition, analysis, and interpretation of data, revised it critically and gave final approval of the version to be published	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Resources|Writing - Review & Editing	YES
6029905	30061796	Dz.S.	2	gave substantial contributions to the conception, design, acquisition, analysis, and interpretation of data, revised it critically and gave final approval of the version to be published	gave substantial contributions to the conception, design, acquisition, analysis, and interpretation of data, revised it critically and gave final approval of the version to be published	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Resources|Writing - Review & Editing	YES
6029905	30061796	Each author	2	gave agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	gave agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	-	-	NO
6029905	30061796	O.C.I.	2	gave substantial contributions to the conception, design, acquisition, analysis, and interpretation of data, revised it critically and gave final approval of the version to be published	gave substantial contributions to the conception, design, acquisition, analysis, and interpretation of data, revised it critically and gave final approval of the version to be published	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Resources|Writing - Review & Editing	YES
6029905	30061796	Z.D.	2	gave substantial contributions to the conception, design, acquisition, analysis, and interpretation of data, revised it critically and gave final approval of the version to be published	gave substantial contributions to the conception, design, acquisition, analysis, and interpretation of data, revised it critically and gave final approval of the version to be published	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Resources|Writing - Review & Editing	YES
6321157	30261580	F.T.	CRediT	Visualization|Funding acquisition	Visualization	Analyzed the data	Visualization	YES
6321157	30261580	F.T.	CRediT	Visualization|Funding acquisition	Funding acquisition	-	Funding acquisition	YES
6321157	30261580	R.R.	CRediT	Conceptualization|Investigation|Visualization|Supervision|Project administration	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6321157	30261580	R.R.	CRediT	Conceptualization|Investigation|Visualization|Supervision|Project administration	Investigation	Performed the experiments	Investigation	YES
6321157	30261580	R.R.	CRediT	Conceptualization|Investigation|Visualization|Supervision|Project administration	Visualization	Analyzed the data	Visualization	YES
6321157	30261580	R.R.	CRediT	Conceptualization|Investigation|Visualization|Supervision|Project administration	Supervision	-	Supervision	YES
6321157	30261580	R.R.	CRediT	Conceptualization|Investigation|Visualization|Supervision|Project administration	Project administration	-	Project administration	YES
6321157	30261580	S.K.	CRediT	Methodology|Validation|Writing-original draft preparation	Methodology	Performed the experiments	Methodology	YES
6321157	30261580	S.K.	CRediT	Methodology|Validation|Writing-original draft preparation	Validation	Performed the experiments	Validation	YES
6321157	30261580	S.K.	CRediT	Methodology|Validation|Writing-original draft preparation	Writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
4385658	25874222	Chisato Fujimoto	2	equally contributed to the study	equally contributed to the study	-	-	NO
4385658	25874222	Teru Kamogashira	2	equally contributed to the study	equally contributed to the study	-	-	NO
4986251	27526683	BO	2	contributed in the design of the study, interpretation of the results, writing of the manuscript, revision of its content and approval of the final version submitted for publication|realized laboratory analyses	contributed in the design of the study, interpretation of the results, writing of the manuscript, revision of its content and approval of the final version submitted for publication	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
4986251	27526683	BO	2	contributed in the design of the study, interpretation of the results, writing of the manuscript, revision of its content and approval of the final version submitted for publication|realized laboratory analyses	realized laboratory analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4986251	27526683	CLG	2	contributed in the design of the study, interpretation of the results, writing of the manuscript, revision of its content and approval of the final version submitted for publication|was the principal investigator of the project	contributed in the design of the study, interpretation of the results, writing of the manuscript, revision of its content and approval of the final version submitted for publication	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
4986251	27526683	CLG	2	contributed in the design of the study, interpretation of the results, writing of the manuscript, revision of its content and approval of the final version submitted for publication|was the principal investigator of the project	was the principal investigator of the project	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
4986251	27526683	MD	2	contributed in the design of the study, interpretation of the results, writing of the manuscript, revision of its content and approval of the final version submitted for publication|realized the animal phase of the project	contributed in the design of the study, interpretation of the results, writing of the manuscript, revision of its content and approval of the final version submitted for publication	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
4986251	27526683	MD	2	contributed in the design of the study, interpretation of the results, writing of the manuscript, revision of its content and approval of the final version submitted for publication|realized the animal phase of the project	realized the animal phase of the project	-	-	NO
4986251	27526683	N.B.	2	performed microarray analysis and supervised rt-pcr analyses	performed microarray analysis and supervised rt-pcr analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Supervision	YES
4986251	27526683	NB	2	contributed in the design of the study, interpretation of the results, writing of the manuscript, revision of its content and approval of the final version submitted for publication	contributed in the design of the study, interpretation of the results, writing of the manuscript, revision of its content and approval of the final version submitted for publication	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
3061886	21385439	FI	2	designed the proposed method and analyzed the data statistically	designed the proposed method and analyzed the data statistically	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
3061886	21385439	MEKW	2	carried out the experimental work	carried out the experimental work	Performed the experiments	Investigation	YES
3061886	21385439	MIE	2	coordinated the study and modified the text	coordinated the study and modified the text	-	Project administration	YES
3061886	21385439	MKSE	2	proposed, planned and supervised the whole work	proposed, planned and supervised the whole work	Conceived and designed the experiments	Conceptualization|Supervision	YES
5422514	28536594	All authors	2	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5422514	28536594	BL	2	did the qrt pcr, collected voc genes information of other species, and did structural analysis and prepared figures 1 - 7	did the qrt pcr, collected voc genes information of other species, and did structural analysis and prepared figures 1 - 7	Performed the experiments	Investigation|Visualization	YES
5422514	28536594	HL	2	prepared for supplementary information	prepared for supplementary information	-	-	NO
5422514	28536594	ML	2	designed the experiment	designed the experiment	Conceived and designed the experiments	Methodology	YES
5422514	28536594	NR	2	prepared for supplementary information	prepared for supplementary information	-	-	NO
5422514	28536594	NW	2	did multiple alignment of the bnavoc genes and made the phylogenetic analysis|did the qrt pcr, collected voc genes information of other species, and did structural analysis and prepared figures 1 - 7	did multiple alignment of the bnavoc genes and made the phylogenetic analysis	Performed the experiments	Investigation	YES
5422514	28536594	NW	2	did multiple alignment of the bnavoc genes and made the phylogenetic analysis|did the qrt pcr, collected voc genes information of other species, and did structural analysis and prepared figures 1 - 7	did the qrt pcr, collected voc genes information of other species, and did structural analysis and prepared figures 1 - 7	Performed the experiments	Investigation|Visualization	YES
5422514	28536594	YL	2	did the qrt pcr, collected voc genes information of other species, and did structural analysis and prepared figures 1 - 7	did the qrt pcr, collected voc genes information of other species, and did structural analysis and prepared figures 1 - 7	Performed the experiments	Investigation|Visualization	YES
5422514	28536594	YM	2	did the qrt pcr, collected voc genes information of other species, and did structural analysis and prepared figures 1 - 7	did the qrt pcr, collected voc genes information of other species, and did structural analysis and prepared figures 1 - 7	Performed the experiments	Investigation|Visualization	YES
5422514	28536594	YY	2	prepared for supplementary information	prepared for supplementary information	-	-	NO
5422514	28536594	ZC	2	did the qrt pcr, collected voc genes information of other species, and did structural analysis and prepared figures 1 - 7	did the qrt pcr, collected voc genes information of other species, and did structural analysis and prepared figures 1 - 7	Performed the experiments	Investigation|Visualization	YES
5871965	29518007	D.N.M.	2	conceived the experiment and analyzed the data	conceived the experiment and analyzed the data	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
6029907	30061806	All authors	2	participated in each step of research|gave confirmation for final reviesed version to be submitted	participated in each step of research	-	-	NO
6029907	30061806	All authors	2	participated in each step of research|gave confirmation for final reviesed version to be submitted	gave confirmation for final reviesed version to be submitted	-	-	NO
6029907	30061806	N.S.S.H.	2	revised it critically	revised it critically	Wrote the paper	Writing - Review & Editing	YES
4397018	25875960	JL	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397018	25875960	JL	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397018	25875960	LPC	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4397018	25875960	SCW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4397018	25875960	YFZ	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4397018	25875960	ZSF	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
3063190	21396112	GPH	2	contributed with conception, revising the manuscript and gave final approval of the version to be published	contributed with conception, revising the manuscript and gave final approval of the version to be published	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
3063190	21396112	PKJ	2	designed the experiments acquired and analyzed the data and drafted the manuscript	designed the experiments acquired and analyzed the data and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5871966	29534495	M.E.	2	designed the concept behind the paper|is the main contributor to the writing of the paper	designed the concept behind the paper	Conceived and designed the experiments	Conceptualization	YES
5871966	29534495	M.E.	2	designed the concept behind the paper|is the main contributor to the writing of the paper	is the main contributor to the writing of the paper	Wrote the paper	Writing - Original Draft	YES
5871966	29534495	R.W.	2	contributed to the development of the manuscript	contributed to the development of the manuscript	Wrote the paper	Writing - Original Draft	YES
5871966	29534495	Y.L.	2	contributed to the development of the manuscript	contributed to the development of the manuscript	Wrote the paper	Writing - Original Draft	YES
6321168	30453699	J.-Y.S.	CRediT	Methodology|Validation|Writing--original draft preparation	Methodology	Performed the experiments	Methodology	YES
6321168	30453699	J.-Y.S.	CRediT	Methodology|Validation|Writing--original draft preparation	Validation	Performed the experiments	Validation	YES
6321168	30453699	J.-Y.S.	CRediT	Methodology|Validation|Writing--original draft preparation	Writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6321168	30453699	M.-B.Z.	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
6321168	30453699	P.-F.T.	CRediT	Resources	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6321168	30453699	X.-Y.G.	CRediT	Conceptualization|Resources|Writing--review & editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6321168	30453699	X.-Y.G.	CRediT	Conceptualization|Resources|Writing--review & editing	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6321168	30453699	X.-Y.G.	CRediT	Conceptualization|Resources|Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6321168	30453699	Y.-Q.M.	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
6321168	30453699	Y.-Y.L.	CRediT	Methodology|Validation|Investigation|Writing--original draft preparation	Methodology	Performed the experiments	Methodology	YES
6321168	30453699	Y.-Y.L.	CRediT	Methodology|Validation|Investigation|Writing--original draft preparation	Validation	Performed the experiments	Validation	YES
6321168	30453699	Y.-Y.L.	CRediT	Methodology|Validation|Investigation|Writing--original draft preparation	Investigation	Performed the experiments	Investigation	YES
6321168	30453699	Y.-Y.L.	CRediT	Methodology|Validation|Investigation|Writing--original draft preparation	Writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6321168	30453699	Y.J.	CRediT	Resources|Writing--review & editing	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6321168	30453699	Y.J.	CRediT	Resources|Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6321168	30453699	Y.L.	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
5422515	28536595	AA	2	contributed toward the write up in main body of article	contributed toward the write up in main body of article	Wrote the paper	Writing - Original Draft	YES
5422515	28536595	AD	2	reviewed and finalize the article	reviewed and finalize the article	Wrote the paper	Writing - Review & Editing	YES
5422515	28536595	FA	2	contributed toward the write up in main body of article	contributed toward the write up in main body of article	Wrote the paper	Writing - Original Draft	YES
5422515	28536595	FJ	2	contributed toward the write up in main body of article	contributed toward the write up in main body of article	Wrote the paper	Writing - Original Draft	YES
5422515	28536595	HL	2	reviewed and finalize the article	reviewed and finalize the article	Wrote the paper	Writing - Review & Editing	YES
5422515	28536595	MA	2	conceived, designed and mainly develop the article	conceived, designed and mainly develop the article	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4397019	25874946	ILA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397019	25874946	ILA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397019	25874946	ILA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397019	25874946	ILA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397019	25874946	KKYS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397019	25874946	KKYS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397019	25874946	KKYS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397019	25874946	KKYS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397019	25874946	KKYS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6029910	30061803	All authors	2	read, and approved of the final manuscript	read, and approved of the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6029910	30061803	Hasan Siamian	2	extracted the article from thesis and drafted the articled in the style of the journal	extracted the article from thesis and drafted the articled in the style of the journal	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6029910	30061803	J Fallahpour	2	considered and aimed, the study and drafted the thesis|extracted the article from thesis and drafted the articled in the style of the journal	considered and aimed, the study and drafted the thesis	Wrote the paper	Writing - Original Draft	YES
6029910	30061803	J Fallahpour	2	considered and aimed, the study and drafted the thesis|extracted the article from thesis and drafted the articled in the style of the journal	extracted the article from thesis and drafted the articled in the style of the journal	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3068076	21401955	HS	2	participated in data collection and manuscript drafting, completed the molecular design, the arrangement of the work and modification of the manuscript|participated in the separation and purification of compounds, acquisition of data, and collection of literature and helped to draft the manuscript	participated in data collection and manuscript drafting, completed the molecular design, the arrangement of the work and modification of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
3068076	21401955	HS	2	participated in data collection and manuscript drafting, completed the molecular design, the arrangement of the work and modification of the manuscript|participated in the separation and purification of compounds, acquisition of data, and collection of literature and helped to draft the manuscript	participated in the separation and purification of compounds, acquisition of data, and collection of literature and helped to draft the manuscript	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3068076	21401955	SJ-B	2	proposed and supervised the program, and participated in data analysis and draft reversion, coordinated the study and modified the text|participated in the separation and purification of compounds, acquisition of data, and collection of literature and helped to draft the manuscript	proposed and supervised the program, and participated in data analysis and draft reversion, coordinated the study and modified the text	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Project administration|Supervision|Writing - Original Draft	YES
3068076	21401955	SJ-B	2	proposed and supervised the program, and participated in data analysis and draft reversion, coordinated the study and modified the text|participated in the separation and purification of compounds, acquisition of data, and collection of literature and helped to draft the manuscript	participated in the separation and purification of compounds, acquisition of data, and collection of literature and helped to draft the manuscript	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4986254	27526934	CSC	2	offered all computational support	offered all computational support	-	Formal analysis	YES
4986254	27526934	JT	2	performed critical reading and improved the manuscript	performed critical reading and improved the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4986254	27526934	NC	2	conceived the study|did the scripting and data formatting|analyzed the data and wrote the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4986254	27526934	NC	2	conceived the study|did the scripting and data formatting|analyzed the data and wrote the manuscript	did the scripting and data formatting	-	Software	YES
4986254	27526934	NC	2	conceived the study|did the scripting and data formatting|analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4986254	27526934	TT	2	conceived the study|did the bench assays|analyzed the data and wrote the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4986254	27526934	TT	2	conceived the study|did the bench assays|analyzed the data and wrote the manuscript	did the bench assays	Performed the experiments	Investigation	YES
4986254	27526934	TT	2	conceived the study|did the bench assays|analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5871967	29538330	H.A.A.-S.	2	carried out experimentation, data interpretation, and manuscript drafting	carried out experimentation, data interpretation, and manuscript drafting	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5871967	29538330	Z.R.	2	carried out experimentation, data interpretation, and manuscript drafting|conceived of the study, its design, coordination, data interpretation, and manuscript drafting	carried out experimentation, data interpretation, and manuscript drafting	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5871967	29538330	Z.R.	2	carried out experimentation, data interpretation, and manuscript drafting|conceived of the study, its design, coordination, data interpretation, and manuscript drafting	conceived of the study, its design, coordination, data interpretation, and manuscript drafting	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Project administration|Writing - Original Draft	YES
6321172	30513962	B.i.L.	PLoS52	performed the experiments|reviewed the data	performed the experiments	Performed the experiments	Investigation	YES
6321172	30513962	B.i.L.	PLoS52	performed the experiments|reviewed the data	reviewed the data	-	-	NO
6321172	30513962	J.-J.B.	PLoS52	performed the experiments|reviewed the data	performed the experiments	Performed the experiments	Investigation	YES
6321172	30513962	J.-J.B.	PLoS52	performed the experiments|reviewed the data	reviewed the data	-	-	NO
6321172	30513962	J.C.	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
6321172	30513962	M.-H.P.	PLoS52	performed the experiments|reviewed the data	performed the experiments	Performed the experiments	Investigation	YES
6321172	30513962	M.-H.P.	PLoS52	performed the experiments|reviewed the data	reviewed the data	-	-	NO
6321172	30513962	N.K.	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
6321172	30513962	S.-H.S.	PLoS52	designed the experiment|performed the experiments|analyzed and calculated the data|wrote the paper	designed the experiment	Conceived and designed the experiments	Methodology	YES
6321172	30513962	S.-H.S.	PLoS52	designed the experiment|performed the experiments|analyzed and calculated the data|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
6321172	30513962	S.-H.S.	PLoS52	designed the experiment|performed the experiments|analyzed and calculated the data|wrote the paper	analyzed and calculated the data	Analyzed the data	Formal analysis	YES
6321172	30513962	S.-H.S.	PLoS52	designed the experiment|performed the experiments|analyzed and calculated the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6321172	30513962	Y.G.S.	PLoS52	designed the experiment|reviewed the data|reviewed and revised the paper	designed the experiment	Conceived and designed the experiments	Methodology	YES
6321172	30513962	Y.G.S.	PLoS52	designed the experiment|reviewed the data|reviewed and revised the paper	reviewed the data	-	-	NO
6321172	30513962	Y.G.S.	PLoS52	designed the experiment|reviewed the data|reviewed and revised the paper	reviewed and revised the paper	Wrote the paper	Writing - Review & Editing	YES
6321172	30513962	Y.P.	PLoS52	performed the experiments|reviewed the data	performed the experiments	Performed the experiments	Investigation	YES
6321172	30513962	Y.P.	PLoS52	performed the experiments|reviewed the data	reviewed the data	-	-	NO
5422516	28536587	All authors	2	approved this manuscript for publication	approved this manuscript for publication	-	-	NO
5422516	28536587	FL	2	revised the paper	revised the paper	Wrote the paper	Writing - Review & Editing	YES
5422516	28536587	RZ	2	revised the paper	revised the paper	Wrote the paper	Writing - Review & Editing	YES
5422516	28536587	WL	2	revised the paper	revised the paper	Wrote the paper	Writing - Review & Editing	YES
4397021	25875397	MIH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397021	25875397	MIH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397021	25875397	MIH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397021	25875397	MIH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397021	25875397	MIH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397021	25875397	MNK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397021	25875397	MNK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397021	25875397	MNK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397021	25875397	MNK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397021	25875397	MNK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397021	25875397	TA	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397021	25875397	TS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397021	25875397	TS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397021	25875397	TS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397021	25875397	TS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397021	25875397	TS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4986259	27528457	AIS	2	conceived of the project|contributed to peptide mapping and functional analysis	conceived of the project	Conceived and designed the experiments	Conceptualization	YES
4986259	27528457	AIS	2	conceived of the project|contributed to peptide mapping and functional analysis	contributed to peptide mapping and functional analysis	Performed the experiments	Investigation	YES
4986259	27528457	DWW	2	conceived of the project|wrote the manuscript and all authors contributed to the editing of the manuscript	conceived of the project	Conceived and designed the experiments	Conceptualization	YES
4986259	27528457	DWW	2	conceived of the project|wrote the manuscript and all authors contributed to the editing of the manuscript	wrote the manuscript and all authors contributed to the editing of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4986259	27528457	GSS	2	analyzed tandem ms data|contributed to peptide mapping and functional analysis|wrote the manuscript and all authors contributed to the editing of the manuscript	analyzed tandem ms data	Analyzed the data	Formal analysis	YES
4986259	27528457	GSS	2	analyzed tandem ms data|contributed to peptide mapping and functional analysis|wrote the manuscript and all authors contributed to the editing of the manuscript	contributed to peptide mapping and functional analysis	Performed the experiments	Investigation	YES
4986259	27528457	GSS	2	analyzed tandem ms data|contributed to peptide mapping and functional analysis|wrote the manuscript and all authors contributed to the editing of the manuscript	wrote the manuscript and all authors contributed to the editing of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4986259	27528457	JCD	2	assisted with technical aspects of large database generation, parallelization, and queries	assisted with technical aspects of large database generation, parallelization, and queries	Contributed reagents/materials/analysis tools	Software	YES
4986259	27528457	JRY	2	conceived of the project	conceived of the project	Conceived and designed the experiments	Conceptualization	YES
4986259	27528457	SC	2	performed wet lab experiments and collected tandem ms data|analyzed tandem ms data|wrote the manuscript and all authors contributed to the editing of the manuscript	performed wet lab experiments and collected tandem ms data	Performed the experiments	Investigation	YES
4986259	27528457	SC	2	performed wet lab experiments and collected tandem ms data|analyzed tandem ms data|wrote the manuscript and all authors contributed to the editing of the manuscript	analyzed tandem ms data	Analyzed the data	Formal analysis	YES
4986259	27528457	SC	2	performed wet lab experiments and collected tandem ms data|analyzed tandem ms data|wrote the manuscript and all authors contributed to the editing of the manuscript	wrote the manuscript and all authors contributed to the editing of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6321178	30453642	J.W.	PLoS52	conceived and designed the experiments|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6321178	30453642	J.W.	PLoS52	conceived and designed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6321178	30453642	Jiaoyan Liu	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
6321178	30453642	Jing Li	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
6321178	30453642	Q.M.	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
6321178	30453642	Y.W.	PLoS52	conceived and designed the experiments|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6321178	30453642	Y.W.	PLoS52	conceived and designed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3076224	21463509	All authors	2	contributed significantly in the drafting of the manuscript	contributed significantly in the drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
3076224	21463509	BK	2	performed the statistical analysis, and the interpretation of the results	performed the statistical analysis, and the interpretation of the results	Analyzed the data	Formal analysis	YES
3076224	21463509	DR	2	performed the mathematical modeling, supervised, and directed the study	performed the mathematical modeling, supervised, and directed the study	Performed the experiments	Formal analysis|Investigation|Methodology|Supervision	YES
3076224	21463509	IS	2	designed, and performed the experimentation	designed, and performed the experimentation	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5871968	29562587	All authors	2	contributed to data interpretation and approved the manuscript	contributed to data interpretation and approved the manuscript	Analyzed the data	Formal analysis	YES
5871968	29562587	G.C.	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5871968	29562587	G.Ci	2	conceptualized the study|revised the manuscript and the final version	conceptualized the study	Conceived and designed the experiments	Conceptualization	YES
5871968	29562587	G.Ci	2	conceptualized the study|revised the manuscript and the final version	revised the manuscript and the final version	Wrote the paper	Writing - Review & Editing	YES
5871968	29562587	M.D.P.	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5871968	29562587	P.G.	2	conceptualized the study	conceptualized the study	Conceived and designed the experiments	Conceptualization	YES
5871968	29562587	S.D.	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6029911	30061798	HM	1	Study conception and design|Acquisition of data|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content	Study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6029911	30061798	HM	1	Study conception and design|Acquisition of data|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content	Acquisition of data	Performed the experiments	Investigation	YES
6029911	30061798	HM	1	Study conception and design|Acquisition of data|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content	Drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
6029911	30061798	HM	1	Study conception and design|Acquisition of data|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content	Critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
6029911	30061798	MM	1	Study conception and design|Acquisition of data|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content	Study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6029911	30061798	MM	1	Study conception and design|Acquisition of data|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content	Acquisition of data	Performed the experiments	Investigation	YES
6029911	30061798	MM	1	Study conception and design|Acquisition of data|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content	Drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
6029911	30061798	MM	1	Study conception and design|Acquisition of data|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content	Critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
6029911	30061798	MT	1	Study conception and design|Study conception and design|Statistical analysis and interpretation of data|Drafting of the manuscript|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content|Critical revision of the manuscript for important intellectual content	Study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6029911	30061798	MT	1	Study conception and design|Study conception and design|Statistical analysis and interpretation of data|Drafting of the manuscript|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content|Critical revision of the manuscript for important intellectual content	Study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6029911	30061798	MT	1	Study conception and design|Study conception and design|Statistical analysis and interpretation of data|Drafting of the manuscript|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content|Critical revision of the manuscript for important intellectual content	Statistical analysis and interpretation of data	Analyzed the data	Formal analysis	YES
6029911	30061798	MT	1	Study conception and design|Study conception and design|Statistical analysis and interpretation of data|Drafting of the manuscript|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content|Critical revision of the manuscript for important intellectual content	Drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
6029911	30061798	MT	1	Study conception and design|Study conception and design|Statistical analysis and interpretation of data|Drafting of the manuscript|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content|Critical revision of the manuscript for important intellectual content	Drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
6029911	30061798	MT	1	Study conception and design|Study conception and design|Statistical analysis and interpretation of data|Drafting of the manuscript|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content|Critical revision of the manuscript for important intellectual content	Critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
6029911	30061798	MT	1	Study conception and design|Study conception and design|Statistical analysis and interpretation of data|Drafting of the manuscript|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content|Critical revision of the manuscript for important intellectual content	Critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5422517	28536592	AA	2	conceived the study|conducted experiments|analyzed data|wrote the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5422517	28536592	AA	2	conceived the study|conducted experiments|analyzed data|wrote the manuscript	conducted experiments	Performed the experiments	Investigation	YES
5422517	28536592	AA	2	conceived the study|conducted experiments|analyzed data|wrote the manuscript	analyzed data	Analyzed the data	Formal analysis	YES
5422517	28536592	AA	2	conceived the study|conducted experiments|analyzed data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5422517	28536592	All authors	2	read and approved the manuscript	read and approved the manuscript	-	-	NO
5422517	28536592	DA	2	analyzed data|contributed to writing	analyzed data	Analyzed the data	Formal analysis	YES
5422517	28536592	DA	2	analyzed data|contributed to writing	contributed to writing	Wrote the paper	-	YES
5422517	28536592	MB	2	conceived the study|wrote the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5422517	28536592	MB	2	conceived the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5422517	28536592	TS	2	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
6321179	30428555	A.D.	CRediT	Conceptualization|Methodology|Supervision|Validation|Visualization|Writing--original draft|Writing--review & editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6321179	30428555	A.D.	CRediT	Conceptualization|Methodology|Supervision|Validation|Visualization|Writing--original draft|Writing--review & editing	Methodology	Performed the experiments	Methodology	YES
6321179	30428555	A.D.	CRediT	Conceptualization|Methodology|Supervision|Validation|Visualization|Writing--original draft|Writing--review & editing	Supervision	-	Supervision	YES
6321179	30428555	A.D.	CRediT	Conceptualization|Methodology|Supervision|Validation|Visualization|Writing--original draft|Writing--review & editing	Validation	Performed the experiments	Validation	YES
6321179	30428555	A.D.	CRediT	Conceptualization|Methodology|Supervision|Validation|Visualization|Writing--original draft|Writing--review & editing	Visualization	Analyzed the data	Visualization	YES
6321179	30428555	A.D.	CRediT	Conceptualization|Methodology|Supervision|Validation|Visualization|Writing--original draft|Writing--review & editing	Writing--original draft	Wrote the paper	Writing - Original Draft	YES
6321179	30428555	A.D.	CRediT	Conceptualization|Methodology|Supervision|Validation|Visualization|Writing--original draft|Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6321179	30428555	C.C.	CRediT	Conceptualization|Methodology|Visualization	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6321179	30428555	C.C.	CRediT	Conceptualization|Methodology|Visualization	Methodology	Performed the experiments	Methodology	YES
6321179	30428555	C.C.	CRediT	Conceptualization|Methodology|Visualization	Visualization	Analyzed the data	Visualization	YES
6321179	30428555	D.I.	CRediT	Conceptualization|Data curation|Formal analysis|Funding acquisition|Investigation|Methodology|Project administration|Resources|Supervision|Validation|Visualization|Writing--original draft|Writing--review & editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6321179	30428555	D.I.	CRediT	Conceptualization|Data curation|Formal analysis|Funding acquisition|Investigation|Methodology|Project administration|Resources|Supervision|Validation|Visualization|Writing--original draft|Writing--review & editing	Data curation	Analyzed the data	Data curation	YES
6321179	30428555	D.I.	CRediT	Conceptualization|Data curation|Formal analysis|Funding acquisition|Investigation|Methodology|Project administration|Resources|Supervision|Validation|Visualization|Writing--original draft|Writing--review & editing	Formal analysis	Analyzed the data	Formal analysis	YES
6321179	30428555	D.I.	CRediT	Conceptualization|Data curation|Formal analysis|Funding acquisition|Investigation|Methodology|Project administration|Resources|Supervision|Validation|Visualization|Writing--original draft|Writing--review & editing	Funding acquisition	-	Funding acquisition	YES
6321179	30428555	D.I.	CRediT	Conceptualization|Data curation|Formal analysis|Funding acquisition|Investigation|Methodology|Project administration|Resources|Supervision|Validation|Visualization|Writing--original draft|Writing--review & editing	Investigation	Performed the experiments	Investigation	YES
6321179	30428555	D.I.	CRediT	Conceptualization|Data curation|Formal analysis|Funding acquisition|Investigation|Methodology|Project administration|Resources|Supervision|Validation|Visualization|Writing--original draft|Writing--review & editing	Methodology	Performed the experiments	Methodology	YES
6321179	30428555	D.I.	CRediT	Conceptualization|Data curation|Formal analysis|Funding acquisition|Investigation|Methodology|Project administration|Resources|Supervision|Validation|Visualization|Writing--original draft|Writing--review & editing	Project administration	-	Project administration	YES
6321179	30428555	D.I.	CRediT	Conceptualization|Data curation|Formal analysis|Funding acquisition|Investigation|Methodology|Project administration|Resources|Supervision|Validation|Visualization|Writing--original draft|Writing--review & editing	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6321179	30428555	D.I.	CRediT	Conceptualization|Data curation|Formal analysis|Funding acquisition|Investigation|Methodology|Project administration|Resources|Supervision|Validation|Visualization|Writing--original draft|Writing--review & editing	Supervision	-	Supervision	YES
6321179	30428555	D.I.	CRediT	Conceptualization|Data curation|Formal analysis|Funding acquisition|Investigation|Methodology|Project administration|Resources|Supervision|Validation|Visualization|Writing--original draft|Writing--review & editing	Validation	Performed the experiments	Validation	YES
6321179	30428555	D.I.	CRediT	Conceptualization|Data curation|Formal analysis|Funding acquisition|Investigation|Methodology|Project administration|Resources|Supervision|Validation|Visualization|Writing--original draft|Writing--review & editing	Visualization	Analyzed the data	Visualization	YES
6321179	30428555	D.I.	CRediT	Conceptualization|Data curation|Formal analysis|Funding acquisition|Investigation|Methodology|Project administration|Resources|Supervision|Validation|Visualization|Writing--original draft|Writing--review & editing	Writing--original draft	Wrote the paper	Writing - Original Draft	YES
6321179	30428555	D.I.	CRediT	Conceptualization|Data curation|Formal analysis|Funding acquisition|Investigation|Methodology|Project administration|Resources|Supervision|Validation|Visualization|Writing--original draft|Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6321179	30428555	M.A.B.	CRediT	Data curation|Formal analysis|Investigation|Methodology|Visualization|Writing--original draft|Writing--review & editing	Data curation	Analyzed the data	Data curation	YES
6321179	30428555	M.A.B.	CRediT	Data curation|Formal analysis|Investigation|Methodology|Visualization|Writing--original draft|Writing--review & editing	Formal analysis	Analyzed the data	Formal analysis	YES
6321179	30428555	M.A.B.	CRediT	Data curation|Formal analysis|Investigation|Methodology|Visualization|Writing--original draft|Writing--review & editing	Investigation	Performed the experiments	Investigation	YES
6321179	30428555	M.A.B.	CRediT	Data curation|Formal analysis|Investigation|Methodology|Visualization|Writing--original draft|Writing--review & editing	Methodology	Performed the experiments	Methodology	YES
6321179	30428555	M.A.B.	CRediT	Data curation|Formal analysis|Investigation|Methodology|Visualization|Writing--original draft|Writing--review & editing	Visualization	Analyzed the data	Visualization	YES
6321179	30428555	M.A.B.	CRediT	Data curation|Formal analysis|Investigation|Methodology|Visualization|Writing--original draft|Writing--review & editing	Writing--original draft	Wrote the paper	Writing - Original Draft	YES
6321179	30428555	M.A.B.	CRediT	Data curation|Formal analysis|Investigation|Methodology|Visualization|Writing--original draft|Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6321179	30428555	M.B.	CRediT	Conceptualization|Data curation|Formal analysis|Funding acquisition|Investigation|Methodology|Project administration|Resources|Supervision|Validation|Visualization|Writing--original draft|Writing--review & editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6321179	30428555	M.B.	CRediT	Conceptualization|Data curation|Formal analysis|Funding acquisition|Investigation|Methodology|Project administration|Resources|Supervision|Validation|Visualization|Writing--original draft|Writing--review & editing	Data curation	Analyzed the data	Data curation	YES
6321179	30428555	M.B.	CRediT	Conceptualization|Data curation|Formal analysis|Funding acquisition|Investigation|Methodology|Project administration|Resources|Supervision|Validation|Visualization|Writing--original draft|Writing--review & editing	Formal analysis	Analyzed the data	Formal analysis	YES
6321179	30428555	M.B.	CRediT	Conceptualization|Data curation|Formal analysis|Funding acquisition|Investigation|Methodology|Project administration|Resources|Supervision|Validation|Visualization|Writing--original draft|Writing--review & editing	Funding acquisition	-	Funding acquisition	YES
6321179	30428555	M.B.	CRediT	Conceptualization|Data curation|Formal analysis|Funding acquisition|Investigation|Methodology|Project administration|Resources|Supervision|Validation|Visualization|Writing--original draft|Writing--review & editing	Investigation	Performed the experiments	Investigation	YES
6321179	30428555	M.B.	CRediT	Conceptualization|Data curation|Formal analysis|Funding acquisition|Investigation|Methodology|Project administration|Resources|Supervision|Validation|Visualization|Writing--original draft|Writing--review & editing	Methodology	Performed the experiments	Methodology	YES
6321179	30428555	M.B.	CRediT	Conceptualization|Data curation|Formal analysis|Funding acquisition|Investigation|Methodology|Project administration|Resources|Supervision|Validation|Visualization|Writing--original draft|Writing--review & editing	Project administration	-	Project administration	YES
6321179	30428555	M.B.	CRediT	Conceptualization|Data curation|Formal analysis|Funding acquisition|Investigation|Methodology|Project administration|Resources|Supervision|Validation|Visualization|Writing--original draft|Writing--review & editing	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6321179	30428555	M.B.	CRediT	Conceptualization|Data curation|Formal analysis|Funding acquisition|Investigation|Methodology|Project administration|Resources|Supervision|Validation|Visualization|Writing--original draft|Writing--review & editing	Supervision	-	Supervision	YES
6321179	30428555	M.B.	CRediT	Conceptualization|Data curation|Formal analysis|Funding acquisition|Investigation|Methodology|Project administration|Resources|Supervision|Validation|Visualization|Writing--original draft|Writing--review & editing	Validation	Performed the experiments	Validation	YES
6321179	30428555	M.B.	CRediT	Conceptualization|Data curation|Formal analysis|Funding acquisition|Investigation|Methodology|Project administration|Resources|Supervision|Validation|Visualization|Writing--original draft|Writing--review & editing	Visualization	Analyzed the data	Visualization	YES
6321179	30428555	M.B.	CRediT	Conceptualization|Data curation|Formal analysis|Funding acquisition|Investigation|Methodology|Project administration|Resources|Supervision|Validation|Visualization|Writing--original draft|Writing--review & editing	Writing--original draft	Wrote the paper	Writing - Original Draft	YES
6321179	30428555	M.B.	CRediT	Conceptualization|Data curation|Formal analysis|Funding acquisition|Investigation|Methodology|Project administration|Resources|Supervision|Validation|Visualization|Writing--original draft|Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6321179	30428555	M.P.	CRediT	Conceptualization|Data curation|Formal analysis|Investigation|Methodology|Visualization|Writing--original draft|Writing--review & editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6321179	30428555	M.P.	CRediT	Conceptualization|Data curation|Formal analysis|Investigation|Methodology|Visualization|Writing--original draft|Writing--review & editing	Data curation	Analyzed the data	Data curation	YES
6321179	30428555	M.P.	CRediT	Conceptualization|Data curation|Formal analysis|Investigation|Methodology|Visualization|Writing--original draft|Writing--review & editing	Formal analysis	Analyzed the data	Formal analysis	YES
6321179	30428555	M.P.	CRediT	Conceptualization|Data curation|Formal analysis|Investigation|Methodology|Visualization|Writing--original draft|Writing--review & editing	Investigation	Performed the experiments	Investigation	YES
6321179	30428555	M.P.	CRediT	Conceptualization|Data curation|Formal analysis|Investigation|Methodology|Visualization|Writing--original draft|Writing--review & editing	Methodology	Performed the experiments	Methodology	YES
6321179	30428555	M.P.	CRediT	Conceptualization|Data curation|Formal analysis|Investigation|Methodology|Visualization|Writing--original draft|Writing--review & editing	Visualization	Analyzed the data	Visualization	YES
6321179	30428555	M.P.	CRediT	Conceptualization|Data curation|Formal analysis|Investigation|Methodology|Visualization|Writing--original draft|Writing--review & editing	Writing--original draft	Wrote the paper	Writing - Original Draft	YES
6321179	30428555	M.P.	CRediT	Conceptualization|Data curation|Formal analysis|Investigation|Methodology|Visualization|Writing--original draft|Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
4986578	21138541	FCJ	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4986578	21138541	JMC	PLoS5	Conceived, designed and supervised the surveillance system|Analyzed the data|Wrote the paper	Conceived, designed and supervised the surveillance system	Conceived and designed the experiments	Conceptualization|Supervision	YES
4986578	21138541	JMC	PLoS5	Conceived, designed and supervised the surveillance system|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4986578	21138541	JMC	PLoS5	Conceived, designed and supervised the surveillance system|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4986578	21138541	TTY	PLoS5	Conducted diagnostic assays	Conducted diagnostic assays	Performed the experiments	Investigation	YES
4986578	21138541	XLL	PLoS5	Conducted diagnostic assays	Conducted diagnostic assays	Performed the experiments	Investigation	YES
4986578	21138541	YY	PLoS5	Conducted diagnostic assays	Conducted diagnostic assays	Performed the experiments	Investigation	YES
4986578	21138541	ZGW	PLoS5	Conceived, designed and supervised the surveillance system|Analyzed the data|Wrote the paper	Conceived, designed and supervised the surveillance system	Conceived and designed the experiments	Conceptualization|Supervision	YES
4986578	21138541	ZGW	PLoS5	Conceived, designed and supervised the surveillance system|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4986578	21138541	ZGW	PLoS5	Conceived, designed and supervised the surveillance system|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4986578	21138541	ZYW	PLoS5	Conceived, designed and supervised the surveillance system|Analyzed the data	Conceived, designed and supervised the surveillance system	Conceived and designed the experiments	Conceptualization|Supervision	YES
4986578	21138541	ZYW	PLoS5	Conceived, designed and supervised the surveillance system|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
6023276	29762473	A.S.	2	conceived the idea for this research|collected the data, analyzed the results and drafted the first manuscript	conceived the idea for this research	Conceived and designed the experiments	Conceptualization	YES
6023276	29762473	A.S.	2	conceived the idea for this research|collected the data, analyzed the results and drafted the first manuscript	collected the data, analyzed the results and drafted the first manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6023276	29762473	All authors	2	reviewed and participated in the revision of the article	reviewed and participated in the revision of the article	Wrote the paper	Writing - Review & Editing	YES
6023276	29762473	H.R.	2	completed the data analysis and completed the methods section	completed the data analysis and completed the methods section	Performed the experiments|Analyzed the data	Formal analysis	YES
6023276	29762473	J.H.	2	conceived the idea for this research|completed the map	conceived the idea for this research	Conceived and designed the experiments	Conceptualization	YES
6023276	29762473	J.H.	2	conceived the idea for this research|completed the map	completed the map	-	-	NO
6023276	29762473	M.H.	2	completed the data analysis and completed the methods section	completed the data analysis and completed the methods section	Performed the experiments|Analyzed the data	Formal analysis	YES
6023276	29762473	R.K.	2	completed the data analysis and completed the methods section	completed the data analysis and completed the methods section	Performed the experiments|Analyzed the data	Formal analysis	YES
3080277	21463512	CJP	2	directed the research	directed the research	-	Supervision	YES
3080277	21463512	CL	2	aided in the data analysis	aided in the data analysis	Analyzed the data	Formal analysis	YES
3080277	21463512	DBW	2	conducted the ageing study	conducted the ageing study	Performed the experiments	Investigation	YES
3080277	21463512	MGD	2	aided in the data analysis	aided in the data analysis	Analyzed the data	Formal analysis	YES
4397024	25874773	AJO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397024	25874773	AJO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397024	25874773	AJO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397024	25874773	AJO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397024	25874773	BLC	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397024	25874773	JP	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4397024	25874773	MAK	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397024	25874773	MAK	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397024	25874773	NJG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397024	25874773	NJG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397024	25874773	NJG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6029913	30061799	Ahmad Saeedi	2	considered and aimed, the study and drafted the final manuscript and conceived of the study, participated in disseminating and, collecting the survey	considered and aimed, the study and drafted the final manuscript and conceived of the study, participated in disseminating and, collecting the survey	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
6029913	30061799	All authors	2	read, and approved of the final manuscript	read, and approved of the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6029913	30061799	Mahyar Salavati	2	considered and aimed, the study and drafted the final manuscript and conceived of the study, participated in disseminating and, collecting the survey	considered and aimed, the study and drafted the final manuscript and conceived of the study, participated in disseminating and, collecting the survey	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
6029913	30061799	Masoud Gharib	2	considered and aimed, the study and drafted the final manuscript and conceived of the study, participated in disseminating and, collecting the survey	considered and aimed, the study and drafted the final manuscript and conceived of the study, participated in disseminating and, collecting the survey	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
6029913	30061799	Roshanak Vameghi	2	considered and aimed, the study and drafted the final manuscript and conceived of the study, participated in disseminating and, collecting the survey	considered and aimed, the study and drafted the final manuscript and conceived of the study, participated in disseminating and, collecting the survey	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
6029913	30061799	Seyed Ali Hosseini	2	considered and aimed, the study and drafted the final manuscript and conceived of the study, participated in disseminating and, collecting the survey	considered and aimed, the study and drafted the final manuscript and conceived of the study, participated in disseminating and, collecting the survey	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
6321204	30563294	A.K.H.	CRediT	methodology	methodology	Performed the experiments	Methodology	YES
6321204	30563294	A.K.W.	CRediT	Conceptualization|investigation|resources|writing--review and editing|project administration|funding acquisition	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6321204	30563294	A.K.W.	CRediT	Conceptualization|investigation|resources|writing--review and editing|project administration|funding acquisition	investigation	Performed the experiments	Investigation	YES
6321204	30563294	A.K.W.	CRediT	Conceptualization|investigation|resources|writing--review and editing|project administration|funding acquisition	resources	Contributed reagents/materials/analysis tools	Resources	YES
6321204	30563294	A.K.W.	CRediT	Conceptualization|investigation|resources|writing--review and editing|project administration|funding acquisition	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6321204	30563294	A.K.W.	CRediT	Conceptualization|investigation|resources|writing--review and editing|project administration|funding acquisition	project administration	-	Project administration	YES
6321204	30563294	A.K.W.	CRediT	Conceptualization|investigation|resources|writing--review and editing|project administration|funding acquisition	funding acquisition	-	Funding acquisition	YES
6321204	30563294	A.N.	CRediT	resources|data curation|writing--review and editing	resources	Contributed reagents/materials/analysis tools	Resources	YES
6321204	30563294	A.N.	CRediT	resources|data curation|writing--review and editing	data curation	Analyzed the data	Data curation	YES
6321204	30563294	A.N.	CRediT	resources|data curation|writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6321204	30563294	A.S.-A.	CRediT	methodology|investigation|data curation	methodology	Performed the experiments	Methodology	YES
6321204	30563294	A.S.-A.	CRediT	methodology|investigation|data curation	investigation	Performed the experiments	Investigation	YES
6321204	30563294	A.S.-A.	CRediT	methodology|investigation|data curation	data curation	Analyzed the data	Data curation	YES
6321204	30563294	C.Z.	CRediT	data curation	data curation	Analyzed the data	Data curation	YES
6321204	30563294	F.Y.H.	CRediT	Conceptualization|formal analysis|investigation|data curation|writing--original draft preparation|writing--review and editing|project administration	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6321204	30563294	F.Y.H.	CRediT	Conceptualization|formal analysis|investigation|data curation|writing--original draft preparation|writing--review and editing|project administration	formal analysis	Analyzed the data	Formal analysis	YES
6321204	30563294	F.Y.H.	CRediT	Conceptualization|formal analysis|investigation|data curation|writing--original draft preparation|writing--review and editing|project administration	investigation	Performed the experiments	Investigation	YES
6321204	30563294	F.Y.H.	CRediT	Conceptualization|formal analysis|investigation|data curation|writing--original draft preparation|writing--review and editing|project administration	data curation	Analyzed the data	Data curation	YES
6321204	30563294	F.Y.H.	CRediT	Conceptualization|formal analysis|investigation|data curation|writing--original draft preparation|writing--review and editing|project administration	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6321204	30563294	F.Y.H.	CRediT	Conceptualization|formal analysis|investigation|data curation|writing--original draft preparation|writing--review and editing|project administration	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6321204	30563294	F.Y.H.	CRediT	Conceptualization|formal analysis|investigation|data curation|writing--original draft preparation|writing--review and editing|project administration	project administration	-	Project administration	YES
6321204	30563294	M.T.S.	CRediT	Conceptualization|investigation|resources|writing--review and editing|project administration|funding acquisition	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6321204	30563294	M.T.S.	CRediT	Conceptualization|investigation|resources|writing--review and editing|project administration|funding acquisition	investigation	Performed the experiments	Investigation	YES
6321204	30563294	M.T.S.	CRediT	Conceptualization|investigation|resources|writing--review and editing|project administration|funding acquisition	resources	Contributed reagents/materials/analysis tools	Resources	YES
6321204	30563294	M.T.S.	CRediT	Conceptualization|investigation|resources|writing--review and editing|project administration|funding acquisition	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6321204	30563294	M.T.S.	CRediT	Conceptualization|investigation|resources|writing--review and editing|project administration|funding acquisition	project administration	-	Project administration	YES
6321204	30563294	M.T.S.	CRediT	Conceptualization|investigation|resources|writing--review and editing|project administration|funding acquisition	funding acquisition	-	Funding acquisition	YES
6321204	30563294	S.M.H.	CRediT	Conceptualization|methodology|investigation|resources|writing--review and editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6321204	30563294	S.M.H.	CRediT	Conceptualization|methodology|investigation|resources|writing--review and editing	methodology	Performed the experiments	Methodology	YES
6321204	30563294	S.M.H.	CRediT	Conceptualization|methodology|investigation|resources|writing--review and editing	investigation	Performed the experiments	Investigation	YES
6321204	30563294	S.M.H.	CRediT	Conceptualization|methodology|investigation|resources|writing--review and editing	resources	Contributed reagents/materials/analysis tools	Resources	YES
6321204	30563294	S.M.H.	CRediT	Conceptualization|methodology|investigation|resources|writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
3080278	21463533	KU	2	collected data of gene sequences and recombinant protein, and contributed to drafting the manuscript	collected data of gene sequences and recombinant protein, and contributed to drafting the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3080278	21463533	MY	2	generated study design and drafted manuscript	generated study design and drafted manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
3080278	21463533	NS	2	generated study design and drafted manuscript	generated study design and drafted manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
3080278	21463533	SO	2	generated study design and drafted manuscript	generated study design and drafted manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
3080278	21463533	YI	2	collected data of gene sequences and recombinant protein, and contributed to drafting the manuscript	collected data of gene sequences and recombinant protein, and contributed to drafting the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4986275	27527602	AM	1	Conception and design|Experimental part, analysis and interpretation of data	Conception and design	Conceived and designed the experiments	Conceptualization	YES
4986275	27527602	AM	1	Conception and design|Experimental part, analysis and interpretation of data	Experimental part, analysis and interpretation of data	Analyzed the data	Formal analysis	YES
4986275	27527602	DCCT	1	Sample collection and maintaining patient database	Sample collection and maintaining patient database	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
4986275	27527602	DM	1	Conception and design|Experimental part, analysis and interpretation of data	Conception and design	Conceived and designed the experiments	Conceptualization	YES
4986275	27527602	DM	1	Conception and design|Experimental part, analysis and interpretation of data	Experimental part, analysis and interpretation of data	Analyzed the data	Formal analysis	YES
4986275	27527602	DP	1	Experimental part, analysis and interpretation of data|Sample collection and maintaining patient database	Experimental part, analysis and interpretation of data	Analyzed the data	Formal analysis	YES
4986275	27527602	DP	1	Experimental part, analysis and interpretation of data|Sample collection and maintaining patient database	Sample collection and maintaining patient database	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
4986275	27527602	GH	1	Conception and design|Experimental part, analysis and interpretation of data|Sample collection and maintaining patient database	Conception and design	Conceived and designed the experiments	Conceptualization	YES
4986275	27527602	GH	1	Conception and design|Experimental part, analysis and interpretation of data|Sample collection and maintaining patient database	Experimental part, analysis and interpretation of data	Analyzed the data	Formal analysis	YES
4986275	27527602	GH	1	Conception and design|Experimental part, analysis and interpretation of data|Sample collection and maintaining patient database	Sample collection and maintaining patient database	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
4986275	27527602	IB	1	Sample collection and maintaining patient database	Sample collection and maintaining patient database	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
4986275	27527602	IV	1	Sample collection and maintaining patient database	Sample collection and maintaining patient database	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
4986275	27527602	JS	1	Sample collection and maintaining patient database	Sample collection and maintaining patient database	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
4986275	27527602	MJ	1	Experimental part, analysis and interpretation of data	Experimental part, analysis and interpretation of data	Analyzed the data	Formal analysis	YES
4986275	27527602	MS	1	Conception and design|Experimental part, analysis and interpretation of data	Conception and design	Conceived and designed the experiments	Conceptualization	YES
4986275	27527602	MS	1	Conception and design|Experimental part, analysis and interpretation of data	Experimental part, analysis and interpretation of data	Analyzed the data	Formal analysis	YES
4986275	27527602	PZ	1	Experimental part, analysis and interpretation of data	Experimental part, analysis and interpretation of data	Analyzed the data	Formal analysis	YES
4986275	27527602	RZ	1	Conception and design|Sample collection and maintaining patient database	Conception and design	Conceived and designed the experiments	Conceptualization	YES
4986275	27527602	RZ	1	Conception and design|Sample collection and maintaining patient database	Sample collection and maintaining patient database	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
4986275	27527602	SL	1	Sample collection and maintaining patient database	Sample collection and maintaining patient database	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
4986275	27527602	SM	1	Sample collection and maintaining patient database	Sample collection and maintaining patient database	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
4986275	27527602	TT	1	Conception and design	Conception and design	Conceived and designed the experiments	Conceptualization	YES
5422545	28536597	AJ	PLoS52	conceived and designed the experiments|were involved in the development of hifs and the multi-year field trials|were involved in the genotyping of pr-19 and hifs and data analysis	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5422545	28536597	AJ	PLoS52	conceived and designed the experiments|were involved in the development of hifs and the multi-year field trials|were involved in the genotyping of pr-19 and hifs and data analysis	were involved in the development of hifs and the multi-year field trials	-	-	NO
5422545	28536597	AJ	PLoS52	conceived and designed the experiments|were involved in the development of hifs and the multi-year field trials|were involved in the genotyping of pr-19 and hifs and data analysis	were involved in the genotyping of pr-19 and hifs and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5422545	28536597	BT	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5422545	28536597	KG	PLoS52	were involved in the genotyping of pr-19 and hifs and data analysis	were involved in the genotyping of pr-19 and hifs and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5422545	28536597	TW	PLoS52	conceived and designed the experiments|were involved in the development of hifs and the multi-year field trials	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5422545	28536597	TW	PLoS52	conceived and designed the experiments|were involved in the development of hifs and the multi-year field trials	were involved in the development of hifs and the multi-year field trials	-	-	NO
6023281	29677102	Each author	2	has participated sufficiently in the work of drafting the article and/or revising the article for important rational content	has participated sufficiently in the work of drafting the article and/or revising the article for important rational content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4397039	25875840	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397039	25875840	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397039	25875840	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397039	25875840	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397039	25875840	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397039	25875840	AC	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397039	25875840	AC	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397039	25875840	DF	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397039	25875840	DF	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397039	25875840	FR	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397039	25875840	FR	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397039	25875840	FR	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397039	25875840	IM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397039	25875840	IM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397039	25875840	IM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397039	25875840	IM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397039	25875840	IM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397039	25875840	LA	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4397039	25875840	MTT	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4397039	25875840	PHAA	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4397039	25875840	SN	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4397039	25875840	WT	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4397039	25875840	WT	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397039	25875840	ZA	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
3086851	21466671	AASHG-PKG	2	has given valuable suggestion during experiment as well written work	has given valuable suggestion during experiment as well written work	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3086851	21466671	NK	2	has contributed in writing the manuscript	has contributed in writing the manuscript	Wrote the paper	Writing - Original Draft	YES
3086851	21466671	NS	2	participated in the design of the study, carried out sampling, wet digestion of the sample and written work	participated in the design of the study, carried out sampling, wet digestion of the sample and written work	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
3086851	21466671	VNO	2	has contributed in calculation of various uncertainties, which have been identified in the experiments	has contributed in calculation of various uncertainties, which have been identified in the experiments	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6029914	30061795	R.J.	2	developed design and concept of the study|critically revised the article and final approval of the version to be published	developed design and concept of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6029914	30061795	R.J.	2	developed design and concept of the study|critically revised the article and final approval of the version to be published	critically revised the article and final approval of the version to be published	Wrote the paper	Writing - Review & Editing	YES
6029914	30061795	T.C.	2	developed design and concept of the study|developed bia model, performed data interpretation and drafting the article|critically revised the article and final approval of the version to be published	developed design and concept of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6029914	30061795	T.C.	2	developed design and concept of the study|developed bia model, performed data interpretation and drafting the article|critically revised the article and final approval of the version to be published	developed bia model, performed data interpretation and drafting the article	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
6029914	30061795	T.C.	2	developed design and concept of the study|developed bia model, performed data interpretation and drafting the article|critically revised the article and final approval of the version to be published	critically revised the article and final approval of the version to be published	Wrote the paper	Writing - Review & Editing	YES
6029914	30061795	V.T.	2	developed design and concept of the study|contributed to data acquisition|critically revised the article and final approval of the version to be published	developed design and concept of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6029914	30061795	V.T.	2	developed design and concept of the study|contributed to data acquisition|critically revised the article and final approval of the version to be published	contributed to data acquisition	Performed the experiments	Investigation	YES
6029914	30061795	V.T.	2	developed design and concept of the study|contributed to data acquisition|critically revised the article and final approval of the version to be published	critically revised the article and final approval of the version to be published	Wrote the paper	Writing - Review & Editing	YES
4986580	20409209	AE	PLoS5	Conducted diagnostic assays|Analyzed the data|Revised and approved final version of the publication	Conducted diagnostic assays	Performed the experiments	Investigation	YES
4986580	20409209	AE	PLoS5	Conducted diagnostic assays|Analyzed the data|Revised and approved final version of the publication	Analyzed the data	Analyzed the data	Formal analysis	YES
4986580	20409209	AE	PLoS5	Conducted diagnostic assays|Analyzed the data|Revised and approved final version of the publication	Revised and approved final version of the publication	Wrote the paper	Writing - Review & Editing	YES
4986580	20409209	AMF	PLoS5	Conceived, designed and supervised the surveillance system|Wrote the paper|Revised and approved final version of the publication	Conceived, designed and supervised the surveillance system	Conceived and designed the experiments	Conceptualization|Supervision	YES
4986580	20409209	AMF	PLoS5	Conceived, designed and supervised the surveillance system|Wrote the paper|Revised and approved final version of the publication	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4986580	20409209	AMF	PLoS5	Conceived, designed and supervised the surveillance system|Wrote the paper|Revised and approved final version of the publication	Revised and approved final version of the publication	Wrote the paper	Writing - Review & Editing	YES
4986580	20409209	BG	PLoS5	Conceived, designed and supervised the surveillance system|Revised and approved final version of the publication	Conceived, designed and supervised the surveillance system	Conceived and designed the experiments	Conceptualization|Supervision	YES
4986580	20409209	BG	PLoS5	Conceived, designed and supervised the surveillance system|Revised and approved final version of the publication	Revised and approved final version of the publication	Wrote the paper	Writing - Review & Editing	YES
4986580	20409209	FA	PLoS5	Conceived, designed and supervised the surveillance system|Revised and approved final version of the publication	Conceived, designed and supervised the surveillance system	Conceived and designed the experiments	Conceptualization|Supervision	YES
4986580	20409209	FA	PLoS5	Conceived, designed and supervised the surveillance system|Revised and approved final version of the publication	Revised and approved final version of the publication	Wrote the paper	Writing - Review & Editing	YES
4986580	20409209	FM	PLoS5	Conceived, designed and supervised the surveillance system|Revised and approved final version of the publication	Conceived, designed and supervised the surveillance system	Conceived and designed the experiments	Conceptualization|Supervision	YES
4986580	20409209	FM	PLoS5	Conceived, designed and supervised the surveillance system|Revised and approved final version of the publication	Revised and approved final version of the publication	Wrote the paper	Writing - Review & Editing	YES
4986580	20409209	GF	PLoS5	Conceived, designed and supervised the surveillance system|Revised and approved final version of the publication	Conceived, designed and supervised the surveillance system	Conceived and designed the experiments	Conceptualization|Supervision	YES
4986580	20409209	GF	PLoS5	Conceived, designed and supervised the surveillance system|Revised and approved final version of the publication	Revised and approved final version of the publication	Wrote the paper	Writing - Review & Editing	YES
4986580	20409209	JCM	PLoS5	Conceived, designed and supervised the surveillance system|Analyzed the data|Revised and approved final version of the publication	Conceived, designed and supervised the surveillance system	Conceived and designed the experiments	Conceptualization|Supervision	YES
4986580	20409209	JCM	PLoS5	Conceived, designed and supervised the surveillance system|Analyzed the data|Revised and approved final version of the publication	Analyzed the data	Analyzed the data	Formal analysis	YES
4986580	20409209	JCM	PLoS5	Conceived, designed and supervised the surveillance system|Analyzed the data|Revised and approved final version of the publication	Revised and approved final version of the publication	Wrote the paper	Writing - Review & Editing	YES
4986580	20409209	JG	PLoS5	Conceived, designed and supervised the surveillance system|Analyzed the data|Wrote the paper|Revised and approved final version of the publication	Conceived, designed and supervised the surveillance system	Conceived and designed the experiments	Conceptualization|Supervision	YES
4986580	20409209	JG	PLoS5	Conceived, designed and supervised the surveillance system|Analyzed the data|Wrote the paper|Revised and approved final version of the publication	Analyzed the data	Analyzed the data	Formal analysis	YES
4986580	20409209	JG	PLoS5	Conceived, designed and supervised the surveillance system|Analyzed the data|Wrote the paper|Revised and approved final version of the publication	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4986580	20409209	JG	PLoS5	Conceived, designed and supervised the surveillance system|Analyzed the data|Wrote the paper|Revised and approved final version of the publication	Revised and approved final version of the publication	Wrote the paper	Writing - Review & Editing	YES
4986580	20409209	KAL	PLoS5	Conceived, designed and supervised the surveillance system|Analyzed the data|Wrote the paper|Revised and approved final version of the publication	Conceived, designed and supervised the surveillance system	Conceived and designed the experiments	Conceptualization|Supervision	YES
4986580	20409209	KAL	PLoS5	Conceived, designed and supervised the surveillance system|Analyzed the data|Wrote the paper|Revised and approved final version of the publication	Analyzed the data	Analyzed the data	Formal analysis	YES
4986580	20409209	KAL	PLoS5	Conceived, designed and supervised the surveillance system|Analyzed the data|Wrote the paper|Revised and approved final version of the publication	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4986580	20409209	KAL	PLoS5	Conceived, designed and supervised the surveillance system|Analyzed the data|Wrote the paper|Revised and approved final version of the publication	Revised and approved final version of the publication	Wrote the paper	Writing - Review & Editing	YES
4986580	20409209	LR	PLoS5	Conceived, designed and supervised the surveillance system|Analyzed the data|Wrote the paper|Revised and approved final version of the publication	Conceived, designed and supervised the surveillance system	Conceived and designed the experiments	Conceptualization|Supervision	YES
4986580	20409209	LR	PLoS5	Conceived, designed and supervised the surveillance system|Analyzed the data|Wrote the paper|Revised and approved final version of the publication	Analyzed the data	Analyzed the data	Formal analysis	YES
4986580	20409209	LR	PLoS5	Conceived, designed and supervised the surveillance system|Analyzed the data|Wrote the paper|Revised and approved final version of the publication	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4986580	20409209	LR	PLoS5	Conceived, designed and supervised the surveillance system|Analyzed the data|Wrote the paper|Revised and approved final version of the publication	Revised and approved final version of the publication	Wrote the paper	Writing - Review & Editing	YES
4986580	20409209	SJO	PLoS5	Conceived, designed and supervised the surveillance system|Wrote the paper|Revised and approved final version of the publication	Conceived, designed and supervised the surveillance system	Conceived and designed the experiments	Conceptualization|Supervision	YES
4986580	20409209	SJO	PLoS5	Conceived, designed and supervised the surveillance system|Wrote the paper|Revised and approved final version of the publication	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4986580	20409209	SJO	PLoS5	Conceived, designed and supervised the surveillance system|Wrote the paper|Revised and approved final version of the publication	Revised and approved final version of the publication	Wrote the paper	Writing - Review & Editing	YES
4986580	20409209	SL	PLoS5	Conceived, designed and supervised the surveillance system|Contributed reagents/materials/analysis tools|Revised and approved final version of the publication	Conceived, designed and supervised the surveillance system	Conceived and designed the experiments	Conceptualization|Supervision	YES
4986580	20409209	SL	PLoS5	Conceived, designed and supervised the surveillance system|Contributed reagents/materials/analysis tools|Revised and approved final version of the publication	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4986580	20409209	SL	PLoS5	Conceived, designed and supervised the surveillance system|Contributed reagents/materials/analysis tools|Revised and approved final version of the publication	Revised and approved final version of the publication	Wrote the paper	Writing - Review & Editing	YES
4986580	20409209	WA	PLoS5	Conceived, designed and supervised the surveillance system|Analyzed the data|Wrote the paper|Revised and approved final version of the publication	Conceived, designed and supervised the surveillance system	Conceived and designed the experiments	Conceptualization|Supervision	YES
4986580	20409209	WA	PLoS5	Conceived, designed and supervised the surveillance system|Analyzed the data|Wrote the paper|Revised and approved final version of the publication	Analyzed the data	Analyzed the data	Formal analysis	YES
4986580	20409209	WA	PLoS5	Conceived, designed and supervised the surveillance system|Analyzed the data|Wrote the paper|Revised and approved final version of the publication	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4986580	20409209	WA	PLoS5	Conceived, designed and supervised the surveillance system|Analyzed the data|Wrote the paper|Revised and approved final version of the publication	Revised and approved final version of the publication	Wrote the paper	Writing - Review & Editing	YES
6321208	30326565	D.V.	CRediT	Conceptualization|Methodology|Formal analysis|Resources|Writing-original draft preparation|Writing-review & editing|Supervision	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6321208	30326565	D.V.	CRediT	Conceptualization|Methodology|Formal analysis|Resources|Writing-original draft preparation|Writing-review & editing|Supervision	Methodology	Performed the experiments	Methodology	YES
6321208	30326565	D.V.	CRediT	Conceptualization|Methodology|Formal analysis|Resources|Writing-original draft preparation|Writing-review & editing|Supervision	Formal analysis	Analyzed the data	Formal analysis	YES
6321208	30326565	D.V.	CRediT	Conceptualization|Methodology|Formal analysis|Resources|Writing-original draft preparation|Writing-review & editing|Supervision	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6321208	30326565	D.V.	CRediT	Conceptualization|Methodology|Formal analysis|Resources|Writing-original draft preparation|Writing-review & editing|Supervision	Writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
6321208	30326565	D.V.	CRediT	Conceptualization|Methodology|Formal analysis|Resources|Writing-original draft preparation|Writing-review & editing|Supervision	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6321208	30326565	D.V.	CRediT	Conceptualization|Methodology|Formal analysis|Resources|Writing-original draft preparation|Writing-review & editing|Supervision	Supervision	-	Supervision	YES
6321208	30326565	J.M.	CRediT	Methodology|Software|Validation|Formal analysis|Investigation|Data curation|Writing-review & editing	Methodology	Performed the experiments	Methodology	YES
6321208	30326565	J.M.	CRediT	Methodology|Software|Validation|Formal analysis|Investigation|Data curation|Writing-review & editing	Software	Contributed reagents/materials/analysis tools	Software	YES
6321208	30326565	J.M.	CRediT	Methodology|Software|Validation|Formal analysis|Investigation|Data curation|Writing-review & editing	Validation	Performed the experiments	Validation	YES
6321208	30326565	J.M.	CRediT	Methodology|Software|Validation|Formal analysis|Investigation|Data curation|Writing-review & editing	Formal analysis	Analyzed the data	Formal analysis	YES
6321208	30326565	J.M.	CRediT	Methodology|Software|Validation|Formal analysis|Investigation|Data curation|Writing-review & editing	Investigation	Performed the experiments	Investigation	YES
6321208	30326565	J.M.	CRediT	Methodology|Software|Validation|Formal analysis|Investigation|Data curation|Writing-review & editing	Data curation	Analyzed the data	Data curation	YES
6321208	30326565	J.M.	CRediT	Methodology|Software|Validation|Formal analysis|Investigation|Data curation|Writing-review & editing	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6321208	30326565	J.Z.	CRediT	Methodology|Software|Validation|Formal analysis|Investigation|Data curation|Writing-original draft preparation|Writing-review & editing	Methodology	Performed the experiments	Methodology	YES
6321208	30326565	J.Z.	CRediT	Methodology|Software|Validation|Formal analysis|Investigation|Data curation|Writing-original draft preparation|Writing-review & editing	Software	Contributed reagents/materials/analysis tools	Software	YES
6321208	30326565	J.Z.	CRediT	Methodology|Software|Validation|Formal analysis|Investigation|Data curation|Writing-original draft preparation|Writing-review & editing	Validation	Performed the experiments	Validation	YES
6321208	30326565	J.Z.	CRediT	Methodology|Software|Validation|Formal analysis|Investigation|Data curation|Writing-original draft preparation|Writing-review & editing	Formal analysis	Analyzed the data	Formal analysis	YES
6321208	30326565	J.Z.	CRediT	Methodology|Software|Validation|Formal analysis|Investigation|Data curation|Writing-original draft preparation|Writing-review & editing	Investigation	Performed the experiments	Investigation	YES
6321208	30326565	J.Z.	CRediT	Methodology|Software|Validation|Formal analysis|Investigation|Data curation|Writing-original draft preparation|Writing-review & editing	Data curation	Analyzed the data	Data curation	YES
6321208	30326565	J.Z.	CRediT	Methodology|Software|Validation|Formal analysis|Investigation|Data curation|Writing-original draft preparation|Writing-review & editing	Writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
6321208	30326565	J.Z.	CRediT	Methodology|Software|Validation|Formal analysis|Investigation|Data curation|Writing-original draft preparation|Writing-review & editing	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
4397040	25875503	AB	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4397040	25875503	AB	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4397040	25875503	DG	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4397040	25875503	DG	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4397040	25875503	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397040	25875503	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397040	25875503	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397040	25875503	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397040	25875503	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397040	25875503	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397040	25875503	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397040	25875503	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397040	25875503	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397040	25875503	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397040	25875503	KJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397040	25875503	KJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397040	25875503	KJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397040	25875503	KJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397040	25875503	KJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4386680	25879024	Liangliang Xu	2	contributed equally to this work	contributed equally to this work	-	-	NO
4386680	25879024	Yuxin Sun	2	contributed equally to this work	contributed equally to this work	-	-	NO
5422548	28536591	CA	2	conceived the research|provided guidance on downscaling of the climate data	conceived the research	Conceived and designed the experiments	Conceptualization	YES
5422548	28536591	CA	2	conceived the research|provided guidance on downscaling of the climate data	provided guidance on downscaling of the climate data	Contributed reagents/materials/analysis tools	Resources|Supervision	YES
5422548	28536591	DD	2	conceived the research|wrote the manuscript|oversaw the research, and reviewed the manuscript	conceived the research	Conceived and designed the experiments	Conceptualization	YES
5422548	28536591	DD	2	conceived the research|wrote the manuscript|oversaw the research, and reviewed the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5422548	28536591	DD	2	conceived the research|wrote the manuscript|oversaw the research, and reviewed the manuscript	oversaw the research, and reviewed the manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
5422548	28536591	DE	2	provided data and edited the manuscript	provided data and edited the manuscript	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Review & Editing	YES
5422548	28536591	JM	2	provided data and edited the manuscript	provided data and edited the manuscript	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Review & Editing	YES
5422548	28536591	JS	2	provided data and edited the manuscript	provided data and edited the manuscript	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Review & Editing	YES
5422548	28536591	KK	2	designed and implemented the methods and analyzed the data|wrote the manuscript	designed and implemented the methods and analyzed the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5422548	28536591	KK	2	designed and implemented the methods and analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6023284	29702565	A.A.E.	2	critically reviewed the manuscript	critically reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
6023284	29702565	O.A.	2	designed the study, participated in the writing of the paper, and approved the final version of manuscript submitted	designed the study, participated in the writing of the paper, and approved the final version of manuscript submitted	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
6023284	29702565	O.A.O.	2	participated in data analysis and the writing of the paper	participated in data analysis and the writing of the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6023284	29702565	S.A.O.	2	participated in the writing of the paper	participated in the writing of the paper	Wrote the paper	Writing - Original Draft	YES
4986337	27528257	AC	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
4986337	27528257	FG	PLoS52	contributed new reagents/analytic tools	contributed new reagents/analytic tools	Contributed reagents/materials/analysis tools	Resources	YES
4986337	27528257	GL	PLoS52	designed research|performed research|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
4986337	27528257	GL	PLoS52	designed research|performed research|wrote the paper	performed research	Performed the experiments	Investigation	YES
4986337	27528257	GL	PLoS52	designed research|performed research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4986337	27528257	GT	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
4986337	27528257	M-PL	PLoS52	improved the manuscript	improved the manuscript	Wrote the paper	Writing - Review & Editing	YES
4986337	27528257	RA	PLoS52	designed research	designed research	Conceived and designed the experiments	Methodology	YES
4986337	27528257	SC	PLoS52	designed research|analyzed data|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
4986337	27528257	SC	PLoS52	designed research|analyzed data|wrote the paper	analyzed data	Analyzed the data	Formal analysis	YES
4986337	27528257	SC	PLoS52	designed research|analyzed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4986337	27528257	VC	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
3088885	21486494	MG	2	performed experiments, data analysis and wrote the manuscript	performed experiments, data analysis and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6321227	30463341	H.W.	CRediT	Conceptualization|methodology|writing--original draft preparation	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6321227	30463341	H.W.	CRediT	Conceptualization|methodology|writing--original draft preparation	methodology	Performed the experiments	Methodology	YES
6321227	30463341	H.W.	CRediT	Conceptualization|methodology|writing--original draft preparation	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6321227	30463341	H.Y.	CRediT	validation|writing--original draft preparation	validation	Performed the experiments	Validation	YES
6321227	30463341	H.Y.	CRediT	validation|writing--original draft preparation	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6321227	30463341	M.S.R.	CRediT	writing--review and editing|supervision|funding acquisition	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6321227	30463341	M.S.R.	CRediT	writing--review and editing|supervision|funding acquisition	supervision	-	Supervision	YES
6321227	30463341	M.S.R.	CRediT	writing--review and editing|supervision|funding acquisition	funding acquisition	-	Funding acquisition	YES
6321227	30463341	Xiaowen Liang	CRediT	Conceptualization|validation|writing--original draft preparation|writing--review and editing|supervision|funding acquisition	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6321227	30463341	Xiaowen Liang	CRediT	Conceptualization|validation|writing--original draft preparation|writing--review and editing|supervision|funding acquisition	validation	Performed the experiments	Validation	YES
6321227	30463341	Xiaowen Liang	CRediT	Conceptualization|validation|writing--original draft preparation|writing--review and editing|supervision|funding acquisition	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6321227	30463341	Xiaowen Liang	CRediT	Conceptualization|validation|writing--original draft preparation|writing--review and editing|supervision|funding acquisition	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6321227	30463341	Xiaowen Liang	CRediT	Conceptualization|validation|writing--original draft preparation|writing--review and editing|supervision|funding acquisition	supervision	-	Supervision	YES
6321227	30463341	Xiaowen Liang	CRediT	Conceptualization|validation|writing--original draft preparation|writing--review and editing|supervision|funding acquisition	funding acquisition	-	Funding acquisition	YES
6321227	30463341	Xin Liu	CRediT	investigation|writing--review and editing	investigation	Performed the experiments	Investigation	YES
6321227	30463341	Xin Liu	CRediT	investigation|writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6321227	30463341	Z.P.X.	CRediT	methodology|writing--review and editing	methodology	Performed the experiments	Methodology	YES
6321227	30463341	Z.P.X.	CRediT	methodology|writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6029920	30061807	Aikaterini Stavrianou	2	made substantial contribution to conception, design, data collection and drafting the paper	made substantial contribution to conception, design, data collection and drafting the paper	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Investigation|Resources|Writing - Original Draft	YES
6029920	30061807	Alexandra Dimitriadou	2	made substantial contribution in the design and supervision of the research and critically revised the paper	made substantial contribution in the design and supervision of the research and critically revised the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Review & Editing	YES
6029920	30061807	Alexandra Mantoudi	2	made substantial contribution to conception, design, data collection and drafting the paper	made substantial contribution to conception, design, data collection and drafting the paper	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Investigation|Resources|Writing - Original Draft	YES
6029920	30061807	Anna Konstantinidou	2	contributed to data collection	contributed to data collection	Performed the experiments	Investigation	YES
6029920	30061807	Despoina Sapountzi-Krepia	2	made substantial contribution in the design and supervision of the research and critically revised the paper	made substantial contribution in the design and supervision of the research and critically revised the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Review & Editing	YES
6029920	30061807	Eugenia Minasidou	2	made substantial contribution to conception, design, data collection and drafting the paper	made substantial contribution to conception, design, data collection and drafting the paper	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Investigation|Resources|Writing - Original Draft	YES
4397041	25874617	CH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397041	25874617	CH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397041	25874617	CH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397041	25874617	CH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397041	25874617	CH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397041	25874617	MR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397041	25874617	MR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397041	25874617	MR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397041	25874617	MR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397041	25874617	PAP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397041	25874617	PAP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397041	25874617	PAP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397041	25874617	PAP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397041	25874617	PAP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397041	25874617	PMc	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397041	25874617	PMc	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397041	25874617	PMc	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397041	25874617	RH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397041	25874617	RH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397041	25874617	RH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397041	25874617	RP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397041	25874617	RP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397041	25874617	TFC	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397041	25874617	TFC	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3101646	21554686	ANM	2	has formulated the research idea and prepared the manuscript draft version	has formulated the research idea and prepared the manuscript draft version	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
3101646	21554686	RGM	2	prepared the manuscript for submission and coordinated final formulation	prepared the manuscript for submission and coordinated final formulation	Conceived and designed the experiments|Wrote the paper	Conceptualization|Project administration|Writing - Original Draft	YES
3101646	21554686	SNA	2	carried out the synthetic experiments and drafted the manuscript	carried out the synthetic experiments and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3101646	21554686	US	2	collected the x-ray data and performed the structure solution	collected the x-ray data and performed the structure solution	Performed the experiments	Investigation	YES
4986582	22385647	David Bowering	2	contributed to concept, design and revisions	contributed to concept, design and revisions	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
4986582	22385647	David M. Patrick	2	contributed to concept, design and revisions	contributed to concept, design and revisions	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
4986582	22385647	Evan Adams	2	contributed to concept, design and revisions	contributed to concept, design and revisions	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
4986582	22385647	Gaston De Serres	2	contributed to concept/design, analysis, interpretation and revisions	contributed to concept/design, analysis, interpretation and revisions	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Review & Editing	YES
4986582	22385647	Marcus Lem	2	contributed to concept, design and revisions	contributed to concept, design and revisions	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
4986582	22385647	Martin Petric	2	oversaw laboratory testing and contributed to design and revisions	oversaw laboratory testing and contributed to design and revisions	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Review & Editing	YES
4986582	22385647	Patrick Tang	2	oversaw laboratory testing and contributed to design and revisions	oversaw laboratory testing and contributed to design and revisions	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Review & Editing	YES
4986582	22385647	Travis S. Hottes	2	contributed to concept/design, analysis, interpretation and revisions	contributed to concept/design, analysis, interpretation and revisions	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Review & Editing	YES
4986582	22385647	William Osei	2	contributed to concept, design and revisions	contributed to concept, design and revisions	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
3351095	22623891	M. G. Ruiz	2	contributed equally to this work	contributed equally to this work	-	-	NO
3351095	22623891	M. Richard-Greenblatt	2	contributed equally to this work	contributed equally to this work	-	-	NO
5422549	28536588	CX	2	carried out most of the experiments	carried out most of the experiments	Performed the experiments	Investigation	YES
5422549	28536588	CYH	2	carried out most of the experiments	carried out most of the experiments	Performed the experiments	Investigation	YES
5422549	28536588	GYZ	2	carried out most of the experiments	carried out most of the experiments	Performed the experiments	Investigation	YES
5422549	28536588	JZJ	2	designed the experiments and wrote this paper	designed the experiments and wrote this paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5422549	28536588	LCZ	2	carried out most of the experiments|designed the experiments and wrote this paper	carried out most of the experiments	Performed the experiments	Investigation	YES
5422549	28536588	LCZ	2	carried out most of the experiments|designed the experiments and wrote this paper	designed the experiments and wrote this paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5422549	28536588	LFG	2	carried out most of the experiments	carried out most of the experiments	Performed the experiments	Investigation	YES
5422549	28536588	LNZ	2	carried out most of the experiments|designed the experiments and wrote this paper	carried out most of the experiments	Performed the experiments	Investigation	YES
5422549	28536588	LNZ	2	carried out most of the experiments|designed the experiments and wrote this paper	designed the experiments and wrote this paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5422549	28536588	XYK	2	designed the experiments and wrote this paper	designed the experiments and wrote this paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4986339	27527343	CLC	2	collected the public dataset, perform bioinformatics analysis and also drafted the manuscript	collected the public dataset, perform bioinformatics analysis and also drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4986339	27527343	DPC	2	contributed to data analysis and manuscript preparation	contributed to data analysis and manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4986339	27527343	FKW	2	collected the public dataset, perform bioinformatics analysis and also drafted the manuscript	collected the public dataset, perform bioinformatics analysis and also drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4986339	27527343	NXJ	2	conceived this study and prepared the manuscript	conceived this study and prepared the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4986339	27527343	SWN	2	provided the experimental coordination and reviewed the manuscript	provided the experimental coordination and reviewed the manuscript	Wrote the paper	Project administration|Writing - Review & Editing	YES
4986339	27527343	WM	2	contributed to data analysis and manuscript preparation	contributed to data analysis and manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4986339	27527343	WMX	2	contributed to data collection	contributed to data collection	Performed the experiments	Investigation	YES
6023299	29690499	B.D.	2	supervised the collection of data and revised the draft manuscript	supervised the collection of data and revised the draft manuscript	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
6023299	29690499	C.A.-B.	2	conceived the idea, designed the experiments and analyzed the data	conceived the idea, designed the experiments and analyzed the data	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
6023299	29690499	C.A.D.	2	analyzed and interpretated the data collected	analyzed and interpretated the data collected	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6023299	29690499	E.I.	2	supervised the clinical characterization and ensured quality of the laboratory	supervised the clinical characterization and ensured quality of the laboratory	Performed the experiments	Investigation|Supervision	YES
6023299	29690499	E.S.D.	2	drafted the first manuscript	drafted the first manuscript	Wrote the paper	Writing - Original Draft	YES
6023299	29690499	F.S.	2	recruited the patients and collected data	recruited the patients and collected data	Performed the experiments	Investigation	YES
6321229	30336640	C.d.l.T.	CRediT	Writing-original draft preparation	Writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
6321229	30336640	V.C.	CRediT	Writing-review & editing|Funding acquisition	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6321229	30336640	V.C.	CRediT	Writing-review & editing|Funding acquisition	Funding acquisition	-	Funding acquisition	YES
6029923	30061802	Peyman Jafari	2	contributed in planning, literature search, and manuscript editing	contributed in planning, literature search, and manuscript editing	Conceived and designed the experiments|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
6029923	30061802	Seyyed Mohammad Taghi	2	was responsible for the study conception and design, and supervising this study	was responsible for the study conception and design, and supervising this study	Conceived and designed the experiments	Conceptualization|Methodology|Supervision	YES
3113336	21504614	BAE	2	participated in the design of the study, analysis of the data and modification of the manuscript	participated in the design of the study, analysis of the data and modification of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
3113336	21504614	FIH	2	prepared and characterized the organic ligand	prepared and characterized the organic ligand	Performed the experiments	Investigation	YES
3113336	21504614	GAE	2	participated in the design of the study, analysis of the data and modification of the manuscript	participated in the design of the study, analysis of the data and modification of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
3113336	21504614	HSS	2	conceived the study, participated in the sequence alignment and drafted the manuscript|isolated and characterized the complexes	conceived the study, participated in the sequence alignment and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
3113336	21504614	HSS	2	conceived the study, participated in the sequence alignment and drafted the manuscript|isolated and characterized the complexes	isolated and characterized the complexes	Performed the experiments	Investigation	YES
3113336	21504614	MAM	2	isolated and characterized the complexes	isolated and characterized the complexes	Performed the experiments	Investigation	YES
4323767	25685246	AJN	2	were involved in study design	were involved in study design	Conceived and designed the experiments	Methodology	YES
4323767	25685246	All authors	2	edited and commented on the paper and all authors read and approved the final manuscript	edited and commented on the paper and all authors read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4323767	25685246	HS	2	were involved in study design|processed the samples and carried out the molecular techniques|performed the bioinformatics and taxonomic analysis|interpreted the data and authored the manuscript	were involved in study design	Conceived and designed the experiments	Methodology	YES
4323767	25685246	HS	2	were involved in study design|processed the samples and carried out the molecular techniques|performed the bioinformatics and taxonomic analysis|interpreted the data and authored the manuscript	processed the samples and carried out the molecular techniques	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
4323767	25685246	HS	2	were involved in study design|processed the samples and carried out the molecular techniques|performed the bioinformatics and taxonomic analysis|interpreted the data and authored the manuscript	performed the bioinformatics and taxonomic analysis	Performed the experiments	Formal analysis|Investigation	YES
4323767	25685246	HS	2	were involved in study design|processed the samples and carried out the molecular techniques|performed the bioinformatics and taxonomic analysis|interpreted the data and authored the manuscript	interpreted the data and authored the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4323767	25685246	KL	2	performed the bioinformatics and taxonomic analysis	performed the bioinformatics and taxonomic analysis	Performed the experiments	Formal analysis|Investigation	YES
4323767	25685246	KSJ	2	were involved in study design	were involved in study design	Conceived and designed the experiments	Methodology	YES
4323767	25685246	SLJ	2	were involved in study design	were involved in study design	Conceived and designed the experiments	Methodology	YES
4397042	25875247	EM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4397042	25875247	EM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397042	25875247	KW	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397042	25875247	KW	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397042	25875247	MS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397042	25875247	NT	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4397042	25875247	NT	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397042	25875247	PS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4397042	25875247	SP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397042	25875247	SP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397042	25875247	SP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397042	25875247	SP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397042	25875247	YD	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5422550	28536586	JEE	2	investigator, guidance of root phenotyping, manuscript review	investigator, guidance of root phenotyping, manuscript review	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Review & Editing	YES
5422550	28536586	LM-O	2	student, marker assisted selection for development of near isogenic lines, phenotyping, data analysis and interpretation, manuscript preparation	student, marker assisted selection for development of near isogenic lines, phenotyping, data analysis and interpretation, manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5422550	28536586	TF	2	co-principle investigator, guidance of marker assisted selection for development of near isogenic lines, manuscript review	co-principle investigator, guidance of marker assisted selection for development of near isogenic lines, manuscript review	Wrote the paper	Supervision|Writing - Original Draft|Writing - Review & Editing	YES
5422550	28536586	TK	2	co-principle investigator, guidance of marker assisted selection for development of near isogenic lines, manuscript review	co-principle investigator, guidance of marker assisted selection for development of near isogenic lines, manuscript review	Wrote the paper	Supervision|Writing - Original Draft|Writing - Review & Editing	YES
5422550	28536586	YS	2	principle investigator, coordination, supervision and guidance of marker assisted selection for development of near isogenic lines, phenotyping, data analysis and interpretation, manuscript preparation	principle investigator, coordination, supervision and guidance of marker assisted selection for development of near isogenic lines, phenotyping, data analysis and interpretation, manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Project administration|Supervision|Writing - Original Draft	YES
4986361	27526722	All authors	2	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
4986361	27526722	EB	2	initiated the project|conceived and designed the overall project|evaluated the results and wrote the manuscript	initiated the project	Conceived and designed the experiments	Conceptualization	YES
4986361	27526722	EB	2	initiated the project|conceived and designed the overall project|evaluated the results and wrote the manuscript	conceived and designed the overall project	Conceived and designed the experiments	Conceptualization|Methodology	YES
4986361	27526722	EB	2	initiated the project|conceived and designed the overall project|evaluated the results and wrote the manuscript	evaluated the results and wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4986361	27526722	EC	2	carried out the data collection and processing|performed the statistical and simulation analyses|evaluated the results and wrote the manuscript	carried out the data collection and processing	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
4986361	27526722	EC	2	carried out the data collection and processing|performed the statistical and simulation analyses|evaluated the results and wrote the manuscript	performed the statistical and simulation analyses	Analyzed the data	Formal analysis	YES
4986361	27526722	EC	2	carried out the data collection and processing|performed the statistical and simulation analyses|evaluated the results and wrote the manuscript	evaluated the results and wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4986361	27526722	GN	2	conceived and designed the overall project|carried out the data collection and processing|evaluated the results and wrote the manuscript	conceived and designed the overall project	Conceived and designed the experiments	Conceptualization|Methodology	YES
4986361	27526722	GN	2	conceived and designed the overall project|carried out the data collection and processing|evaluated the results and wrote the manuscript	carried out the data collection and processing	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
4986361	27526722	GN	2	conceived and designed the overall project|carried out the data collection and processing|evaluated the results and wrote the manuscript	evaluated the results and wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4986361	27526722	LN	2	initiated the project|revised the manuscript	initiated the project	Conceived and designed the experiments	Conceptualization	YES
4986361	27526722	LN	2	initiated the project|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4986361	27526722	LS	2	performed the statistical and simulation analyses	performed the statistical and simulation analyses	Analyzed the data	Formal analysis	YES
4986361	27526722	SP	2	evaluated the results and wrote the manuscript	evaluated the results and wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4986361	27526722	TN	2	performed the statistical and simulation analyses	performed the statistical and simulation analyses	Analyzed the data	Formal analysis	YES
6195389	30515055	DL	2	have equally contributed to the conception, design, analysis and interpretation of data as well as to the writing of the manuscript	have equally contributed to the conception, design, analysis and interpretation of data as well as to the writing of the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Resources|Writing - Original Draft	YES
6195389	30515055	MG	2	have equally contributed to the conception, design, analysis and interpretation of data as well as to the writing of the manuscript	have equally contributed to the conception, design, analysis and interpretation of data as well as to the writing of the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Resources|Writing - Original Draft	YES
6023302	29642647	A.d.S.	PLoS52	performed histology, immunofluorescence, and electron microscopy analysis	performed histology, immunofluorescence, and electron microscopy analysis	Performed the experiments	Investigation	YES
6023302	29642647	All the authors	PLoS52	have critically discussed, read, and approved the final manuscript	have critically discussed, read, and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6023302	29642647	E.C.	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6023302	29642647	E.V.	PLoS52	were involved in the direct patient care	were involved in the direct patient care	Performed the experiments	Investigation	YES
6023302	29642647	G.M.	PLoS52	were involved in the direct patient care|performed histology, immunofluorescence, and electron microscopy analysis	were involved in the direct patient care	Performed the experiments	Investigation	YES
6023302	29642647	G.M.	PLoS52	were involved in the direct patient care|performed histology, immunofluorescence, and electron microscopy analysis	performed histology, immunofluorescence, and electron microscopy analysis	Performed the experiments	Investigation	YES
6023302	29642647	K.C.	PLoS52	conceived and designed the experiments|performed histology, immunofluorescence, and electron microscopy analysis|wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6023302	29642647	K.C.	PLoS52	conceived and designed the experiments|performed histology, immunofluorescence, and electron microscopy analysis|wrote the manuscript	performed histology, immunofluorescence, and electron microscopy analysis	Performed the experiments	Investigation	YES
6023302	29642647	K.C.	PLoS52	conceived and designed the experiments|performed histology, immunofluorescence, and electron microscopy analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6023302	29642647	M.M.	PLoS52	were involved in the direct patient care|conceived and designed the experiments|wrote the manuscript	were involved in the direct patient care	Performed the experiments	Investigation	YES
6023302	29642647	M.M.	PLoS52	were involved in the direct patient care|conceived and designed the experiments|wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6023302	29642647	M.M.	PLoS52	were involved in the direct patient care|conceived and designed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6321230	30297638	B.H.	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
6321230	30297638	H.J.	CRediT	Conceptualization|Methodology|Writing-review & editing|Supervision	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6321230	30297638	H.J.	CRediT	Conceptualization|Methodology|Writing-review & editing|Supervision	Methodology	Performed the experiments	Methodology	YES
6321230	30297638	H.J.	CRediT	Conceptualization|Methodology|Writing-review & editing|Supervision	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6321230	30297638	H.J.	CRediT	Conceptualization|Methodology|Writing-review & editing|Supervision	Supervision	-	Supervision	YES
6321230	30297638	J.H.	CRediT	Conceptualization|Methodology|Writing-review & editing|Supervision	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6321230	30297638	J.H.	CRediT	Conceptualization|Methodology|Writing-review & editing|Supervision	Methodology	Performed the experiments	Methodology	YES
6321230	30297638	J.H.	CRediT	Conceptualization|Methodology|Writing-review & editing|Supervision	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6321230	30297638	J.H.	CRediT	Conceptualization|Methodology|Writing-review & editing|Supervision	Supervision	-	Supervision	YES
6321230	30297638	J.T.	CRediT	Resources	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6321230	30297638	L.Z.	CRediT	Resources	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6321230	30297638	W.L.	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
6321230	30297638	X.Z.	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
6321230	30297638	Z.C.	CRediT	Conceptualization|Methodology|Investigation|Data curation|Writing-original draft preparation|Writing-review & editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6321230	30297638	Z.C.	CRediT	Conceptualization|Methodology|Investigation|Data curation|Writing-original draft preparation|Writing-review & editing	Methodology	Performed the experiments	Methodology	YES
6321230	30297638	Z.C.	CRediT	Conceptualization|Methodology|Investigation|Data curation|Writing-original draft preparation|Writing-review & editing	Investigation	Performed the experiments	Investigation	YES
6321230	30297638	Z.C.	CRediT	Conceptualization|Methodology|Investigation|Data curation|Writing-original draft preparation|Writing-review & editing	Data curation	Analyzed the data	Data curation	YES
6321230	30297638	Z.C.	CRediT	Conceptualization|Methodology|Investigation|Data curation|Writing-original draft preparation|Writing-review & editing	Writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
6321230	30297638	Z.C.	CRediT	Conceptualization|Methodology|Investigation|Data curation|Writing-original draft preparation|Writing-review & editing	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6321230	30297638	Z.D.	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
4397043	25875629	AMJ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4397043	25875629	JD	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4397043	25875629	SDQ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397043	25875629	SDQ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397043	25875629	SDQ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397043	25875629	TL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397043	25875629	TL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397043	25875629	TL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397043	25875629	TL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4986623	21668694	All authors	2	participated in the design, analysis and interpretation of the study	participated in the design, analysis and interpretation of the study	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
4986623	21668694	GK	2	were involved in all phases of the study|assisted jy in data extraction|performed the methodological quality assessment|wrote the manuscript	were involved in all phases of the study	-	-	NO
4986623	21668694	GK	2	were involved in all phases of the study|assisted jy in data extraction|performed the methodological quality assessment|wrote the manuscript	assisted jy in data extraction	Analyzed the data	Data curation	YES
4986623	21668694	GK	2	were involved in all phases of the study|assisted jy in data extraction|performed the methodological quality assessment|wrote the manuscript	performed the methodological quality assessment	Performed the experiments	Investigation|Methodology|Validation	YES
4986623	21668694	GK	2	were involved in all phases of the study|assisted jy in data extraction|performed the methodological quality assessment|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4986623	21668694	HR	2	performed the methodological quality assessment	performed the methodological quality assessment	Performed the experiments	Investigation|Methodology|Validation	YES
4986623	21668694	IR	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4986623	21668694	JY	2	were involved in all phases of the study|led the statistical analysis|wrote the manuscript	were involved in all phases of the study	-	-	NO
4986623	21668694	JY	2	were involved in all phases of the study|led the statistical analysis|wrote the manuscript	led the statistical analysis	Analyzed the data	Formal analysis	YES
4986623	21668694	JY	2	were involved in all phases of the study|led the statistical analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4986623	21668694	LH	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4986623	21668694	RB	2	were involved in all phases of the study|wrote the manuscript	were involved in all phases of the study	-	-	NO
4986623	21668694	RB	2	were involved in all phases of the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3113337	21554731	FI	2	designed the proposed method and analyzed the data statistically	designed the proposed method and analyzed the data statistically	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
3113337	21554731	MEKW	2	carried out the experimental work	carried out the experimental work	Performed the experiments	Investigation	YES
3113337	21554731	MIE	2	coordinated the study and modified the text	coordinated the study and modified the text	-	Project administration	YES
3113337	21554731	MKSE	2	proposed, planned and supervised the whole work	proposed, planned and supervised the whole work	Conceived and designed the experiments	Conceptualization|Supervision	YES
6195392	30515060	A. Carried	2	out the experiment	out the experiment	-	-	NO
6195392	30515060	All authors	2	discussed the results and contributed to the final manuscript	discussed the results and contributed to the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6195392	30515060	Bouros Evangelos	2	conceived of the presented idea	conceived of the presented idea	Conceived and designed the experiments	Conceptualization	YES
6195392	30515060	Georgios Vasilopoulos	2	supervised the findings of this work	supervised the findings of this work	-	Supervision	YES
6195392	30515060	Ourania Castana	2	supervised the findings of this work	supervised the findings of this work	-	Supervision	YES
6195392	30515060	Vasileios Protogerou	2	developed the theory and performed the computations	developed the theory and performed the computations	Performed the experiments	Formal analysis|Investigation	YES
5422554	28536585	AS	2	was mainly responsible to design and conduct field research as well as analyze and review the obtained data and draft the manuscript	was mainly responsible to design and conduct field research as well as analyze and review the obtained data and draft the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5422554	28536585	AW	2	critically revised the analysis and data interpretation and approved the version, which was submitted for publication	critically revised the analysis and data interpretation and approved the version, which was submitted for publication	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5422554	28536585	All four authors	2	had substantial contribution to the conception, design, implementation, and analysis of the work	had substantial contribution to the conception, design, implementation, and analysis of the work	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5422554	28536585	BM	2	critically revised the analysis and data interpretation and approved the version, which was submitted for publication	critically revised the analysis and data interpretation and approved the version, which was submitted for publication	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5422554	28536585	DN	2	critically revised the analysis and data interpretation and approved the version, which was submitted for publication	critically revised the analysis and data interpretation and approved the version, which was submitted for publication	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
3113338	21569400	All authors	2	discussed the results and commented on the manuscript	discussed the results and commented on the manuscript	-	-	NO
3113338	21569400	ST	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3113338	21569400	YT	2	supervised the project	supervised the project	-	Supervision	YES
3113338	21569400	YY	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6195394	30515054	all authors	2	are equally participated in all steps of preparing this paper	are equally participated in all steps of preparing this paper	-	-	NO
6023321	29723983	C.D.B.	PLoS52	conceived and designed the study, collected the data, analyzed the data, and wrote the paper	conceived and designed the study, collected the data, analyzed the data, and wrote the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
6023321	29723983	D.O.H.	PLoS52	performed statistical analysis and wrote the paper	performed statistical analysis and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6023321	29723983	J.E.M.	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6023321	29723983	J.S.I.	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6023321	29723983	S.A.H.	PLoS52	conceived and designed the study, collected the data, analyzed the data, and wrote the paper	conceived and designed the study, collected the data, analyzed the data, and wrote the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
6321233	30314324	A.I.	2	with inputs from authors|carried out the teixobactin analogues syntheses	with inputs from authors	-	-	NO
6321233	30314324	A.I.	2	with inputs from authors|carried out the teixobactin analogues syntheses	carried out the teixobactin analogues syntheses	Performed the experiments	Investigation	YES
6321233	30314324	A.M.	2	was responsible for the lc-ms analyses	was responsible for the lc-ms analyses	Analyzed the data	Formal analysis	YES
6321233	30314324	A.P.	2	carried out the teixobactin analogues syntheses	carried out the teixobactin analogues syntheses	Performed the experiments	Investigation	YES
6321233	30314324	All authors	2	have given approval to the final version of the manuscript	have given approval to the final version of the manuscript	-	-	NO
6321233	30314324	D.G.L.	2	have contributed to the antibacterial studies	have contributed to the antibacterial studies	-	-	NO
6321233	30314324	E.J.T.	2	have contributed to the antibacterial studies	have contributed to the antibacterial studies	-	-	NO
6321233	30314324	E.T.L.G.	2	have contributed to the antibacterial studies	have contributed to the antibacterial studies	-	-	NO
6321233	30314324	I.S.	2	with inputs from authors	with inputs from authors	-	-	NO
6321233	30314324	R.L.	2	have contributed to the antibacterial studies	have contributed to the antibacterial studies	-	-	NO
6321233	30314324	R.M.	2	carried out the teixobactin analogues syntheses	carried out the teixobactin analogues syntheses	Performed the experiments	Investigation	YES
6321233	30314324	S.S.	2	was responsible for the lc-ms analyses	was responsible for the lc-ms analyses	Analyzed the data	Formal analysis	YES
4986384	27528396	CGB	PLoS52	reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
4986384	27528396	CN	PLoS52	conceived and designed the experiments|arranged kits and reagents|reviewed and edited the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4986384	27528396	CN	PLoS52	conceived and designed the experiments|arranged kits and reagents|reviewed and edited the manuscript	arranged kits and reagents	-	-	NO
4986384	27528396	CN	PLoS52	conceived and designed the experiments|arranged kits and reagents|reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
4986384	27528396	DT	PLoS52	arranged kits and reagents|reviewed and edited the manuscript	arranged kits and reagents	-	-	NO
4986384	27528396	DT	PLoS52	arranged kits and reagents|reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
4986384	27528396	ET	PLoS52	reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
4986384	27528396	KS	PLoS52	conceived and designed the experiments|reviewed and edited the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4986384	27528396	KS	PLoS52	conceived and designed the experiments|reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
4986384	27528396	MAI	PLoS52	conceived and designed the experiments|performed field experiment and blood sampling|interpreted the results and drafted the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4986384	27528396	MAI	PLoS52	conceived and designed the experiments|performed field experiment and blood sampling|interpreted the results and drafted the manuscript	performed field experiment and blood sampling	Performed the experiments	Investigation	YES
4986384	27528396	MAI	PLoS52	conceived and designed the experiments|performed field experiment and blood sampling|interpreted the results and drafted the manuscript	interpreted the results and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4986384	27528396	MH	PLoS52	performed field experiment and blood sampling	performed field experiment and blood sampling	Performed the experiments	Investigation	YES
4986384	27528396	MJU	PLoS52	conceived and designed the experiments|reviewed and edited the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4986384	27528396	MJU	PLoS52	conceived and designed the experiments|reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
4986384	27528396	MP	PLoS52	performed field experiment and blood sampling	performed field experiment and blood sampling	Performed the experiments	Investigation	YES
6195397	30515056	E.H.	2	revised it critically	revised it critically	Wrote the paper	Writing - Review & Editing	YES
6195397	30515056	Each author	2	participated in each step of research|gave final approval for final version of article	participated in each step of research	-	-	NO
6195397	30515056	Each author	2	participated in each step of research|gave final approval for final version of article	gave final approval for final version of article	-	-	NO
4397044	25874455	BYZ	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4397044	25874455	BYZ	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397044	25874455	CJX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397044	25874455	CJX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397044	25874455	CJX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397044	25874455	CJX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397044	25874455	JMH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4397044	25874455	WH	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397044	25874455	YML	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5422556	28536589	All authors	2	discussed and commented the manuscript	discussed and commented the manuscript	-	-	NO
5422556	28536589	EF	2	performed enzymatic activities	performed enzymatic activities	Performed the experiments	Investigation	YES
5422556	28536589	EP	2	performed enzymatic activities	performed enzymatic activities	Performed the experiments	Investigation	YES
5422556	28536589	MR	2	performed enzymatic activities	performed enzymatic activities	Performed the experiments	Investigation	YES
6023332	29861477	A.H.	2	contributed to the review concept and design|drafted the manuscript	contributed to the review concept and design	Conceived and designed the experiments	Conceptualization	YES
6023332	29861477	A.H.	2	contributed to the review concept and design|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
6023332	29861477	All authors	2	made critical revision of the article for important intellectual content	made critical revision of the article for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
6023332	29861477	C.A.K.	2	contributed to the review concept and design|drafted the manuscript	contributed to the review concept and design	Conceived and designed the experiments	Conceptualization	YES
6023332	29861477	C.A.K.	2	contributed to the review concept and design|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
6023332	29861477	K.T.L.	2	contributed to the review concept and design|drafted the manuscript	contributed to the review concept and design	Conceived and designed the experiments	Conceptualization	YES
6023332	29861477	K.T.L.	2	contributed to the review concept and design|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
3120737	21545729	NMR	2	spectral analyses	spectral analyses	Analyzed the data	Formal analysis	YES
3120737	21545729	PSB	2	were involved in revising the manuscript	were involved in revising the manuscript	Wrote the paper	Writing - Review & Editing	YES
3120737	21545729	WMX	2	participated in the scientific discussion pertaining to the manuscript	participated in the scientific discussion pertaining to the manuscript	-	-	NO
3120737	21545729	XW	2	performed the antiviral tests	performed the antiviral tests	Performed the experiments	Investigation	YES
3120737	21545729	YJ	2	to carry out his synthesis and characterization experiments|was also involved in the drafting of the manuscript	to carry out his synthesis and characterization experiments	Performed the experiments	Investigation	YES
3120737	21545729	YJ	2	to carry out his synthesis and characterization experiments|was also involved in the drafting of the manuscript	was also involved in the drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
3120737	21545729	ZCW	2	participated in the scientific discussion pertaining to the manuscript	participated in the scientific discussion pertaining to the manuscript	-	-	NO
6195398	30515062	AMA	2	were involved in substantial contribution to acquisition of data and substantial contribution to analysis and interpretation of data	were involved in substantial contribution to acquisition of data and substantial contribution to analysis and interpretation of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
6195398	30515062	All authors	2	revised and approved the manuscript before submission	revised and approved the manuscript before submission	Wrote the paper	Writing - Review & Editing	YES
6195398	30515062	EHA	2	were involved in substantial contribution to acquisition of data and substantial contribution to analysis and interpretation of data	were involved in substantial contribution to acquisition of data and substantial contribution to analysis and interpretation of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
6195398	30515062	HAR	2	were involved in critically revising the article for important intellectual content and final approval of the version to be published	were involved in critically revising the article for important intellectual content and final approval of the version to be published	Wrote the paper	Writing - Review & Editing	YES
6195398	30515062	MRA	2	were involved in critically revising the article for important intellectual content and final approval of the version to be published	were involved in critically revising the article for important intellectual content and final approval of the version to be published	Wrote the paper	Writing - Review & Editing	YES
6195398	30515062	OJA	2	were involved in substantial contribution to acquisition of data and substantial contribution to analysis and interpretation of data	were involved in substantial contribution to acquisition of data and substantial contribution to analysis and interpretation of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
6195398	30515062	RHA	2	were involved in substantial contribution to acquisition of data and substantial contribution to analysis and interpretation of data	were involved in substantial contribution to acquisition of data and substantial contribution to analysis and interpretation of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
6195398	30515062	SNF	2	were involved in substantial contribution to acquisition of data and substantial contribution to analysis and interpretation of data	were involved in substantial contribution to acquisition of data and substantial contribution to analysis and interpretation of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
6195398	30515062	YFA	2	did substantial contribution to conception and design|were involved in substantial contribution to acquisition of data and substantial contribution to analysis and interpretation of data|were involved in critically revising the article for important intellectual content and final approval of the version to be published	did substantial contribution to conception and design	Conceived and designed the experiments	Conceptualization	YES
6195398	30515062	YFA	2	did substantial contribution to conception and design|were involved in substantial contribution to acquisition of data and substantial contribution to analysis and interpretation of data|were involved in critically revising the article for important intellectual content and final approval of the version to be published	were involved in substantial contribution to acquisition of data and substantial contribution to analysis and interpretation of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
6195398	30515062	YFA	2	did substantial contribution to conception and design|were involved in substantial contribution to acquisition of data and substantial contribution to analysis and interpretation of data|were involved in critically revising the article for important intellectual content and final approval of the version to be published	were involved in critically revising the article for important intellectual content and final approval of the version to be published	Wrote the paper	Writing - Review & Editing	YES
6321236	30567289	F.B.	CRediT	Validation	Validation	Performed the experiments	Validation	YES
6321236	30567289	F.H.	CRediT	Methodology	Methodology	Performed the experiments	Methodology	YES
6321236	30567289	M.L.-S.	CRediT	Conceptualization|Writing-review & editing|Supervision|Project administration|Funding acquisition	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6321236	30567289	M.L.-S.	CRediT	Conceptualization|Writing-review & editing|Supervision|Project administration|Funding acquisition	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6321236	30567289	M.L.-S.	CRediT	Conceptualization|Writing-review & editing|Supervision|Project administration|Funding acquisition	Supervision	-	Supervision	YES
6321236	30567289	M.L.-S.	CRediT	Conceptualization|Writing-review & editing|Supervision|Project administration|Funding acquisition	Project administration	-	Project administration	YES
6321236	30567289	M.L.-S.	CRediT	Conceptualization|Writing-review & editing|Supervision|Project administration|Funding acquisition	Funding acquisition	-	Funding acquisition	YES
6321236	30567289	M.S.	CRediT	Conceptualization|Validation|Visualization|Supervision|Project administration|Funding acquisition	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6321236	30567289	M.S.	CRediT	Conceptualization|Validation|Visualization|Supervision|Project administration|Funding acquisition	Validation	Performed the experiments	Validation	YES
6321236	30567289	M.S.	CRediT	Conceptualization|Validation|Visualization|Supervision|Project administration|Funding acquisition	Visualization	Analyzed the data	Visualization	YES
6321236	30567289	M.S.	CRediT	Conceptualization|Validation|Visualization|Supervision|Project administration|Funding acquisition	Supervision	-	Supervision	YES
6321236	30567289	M.S.	CRediT	Conceptualization|Validation|Visualization|Supervision|Project administration|Funding acquisition	Project administration	-	Project administration	YES
6321236	30567289	M.S.	CRediT	Conceptualization|Validation|Visualization|Supervision|Project administration|Funding acquisition	Funding acquisition	-	Funding acquisition	YES
6321236	30567289	N.M.	CRediT	Software	Software	Contributed reagents/materials/analysis tools	Software	YES
6321236	30567289	X.X.	CRediT	Investigation|Resources|Data curation|Writing-original draft preparation	Investigation	Performed the experiments	Investigation	YES
6321236	30567289	X.X.	CRediT	Investigation|Resources|Data curation|Writing-original draft preparation	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6321236	30567289	X.X.	CRediT	Investigation|Resources|Data curation|Writing-original draft preparation	Data curation	Analyzed the data	Data curation	YES
6321236	30567289	X.X.	CRediT	Investigation|Resources|Data curation|Writing-original draft preparation	Writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
6321236	30567289	Y.K.	CRediT	Validation|Formal analysis	Validation	Performed the experiments	Validation	YES
6321236	30567289	Y.K.	CRediT	Validation|Formal analysis	Formal analysis	Analyzed the data	Formal analysis	YES
5423273	28536582	AC	PLoS52	implemented the experiment	implemented the experiment	Performed the experiments	Investigation	YES
5423273	28536582	GP	PLoS52	maintained and oversaw the experiment and assisted in permit process	maintained and oversaw the experiment and assisted in permit process	-	Supervision	YES
5423273	28536582	JAR-V	PLoS52	performed the gas exchange and leaf morphology measurements|analyzed the data	performed the gas exchange and leaf morphology measurements	Performed the experiments	Investigation	YES
5423273	28536582	JAR-V	PLoS52	performed the gas exchange and leaf morphology measurements|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5423273	28536582	JC-B	PLoS52	implemented the experiment|revisions of all authors	implemented the experiment	Performed the experiments	Investigation	YES
5423273	28536582	JC-B	PLoS52	implemented the experiment|revisions of all authors	revisions of all authors	Wrote the paper	Writing - Review & Editing	YES
5423273	28536582	JPS	PLoS52	performed the stable carbon isotope and leaf nitrogen analyses	performed the stable carbon isotope and leaf nitrogen analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5423273	28536582	JRE	PLoS52	implemented the experiment|contributed to design the experiment and data collection	implemented the experiment	Performed the experiments	Investigation	YES
5423273	28536582	JRE	PLoS52	implemented the experiment|contributed to design the experiment and data collection	contributed to design the experiment and data collection	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources	YES
5423273	28536582	KLS	PLoS52	performed the stable carbon isotope and leaf nitrogen analyses	performed the stable carbon isotope and leaf nitrogen analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5423273	28536582	TL	PLoS52	maintained and oversaw the experiment and assisted in permit process	maintained and oversaw the experiment and assisted in permit process	-	Supervision	YES
6023335	29857501	All the authors	2	have critically discussed, read and approved the final manuscript	have critically discussed, read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6023335	29857501	J.A.G.Z.	2	were involved in direct patient care|wrote the manuscript	were involved in direct patient care	Performed the experiments	Investigation	YES
6023335	29857501	J.A.G.Z.	2	were involved in direct patient care|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6023335	29857501	S.H.G.	2	performed histopathology	performed histopathology	Performed the experiments	Investigation	YES
6023335	29857501	Z.H.	2	were involved in direct patient care|wrote the manuscript	were involved in direct patient care	Performed the experiments	Investigation	YES
6023335	29857501	Z.H.	2	were involved in direct patient care|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3123264	21631940	ACHFS	2	have all been involved in drafting this review and have given final approval of the version to be published	have all been involved in drafting this review and have given final approval of the version to be published	Wrote the paper	Writing - Original Draft	YES
3123264	21631940	IBSC	2	have all been involved in drafting this review and have given final approval of the version to be published	have all been involved in drafting this review and have given final approval of the version to be published	Wrote the paper	Writing - Original Draft	YES
3123264	21631940	MCM	2	have all been involved in drafting this review and have given final approval of the version to be published	have all been involved in drafting this review and have given final approval of the version to be published	Wrote the paper	Writing - Original Draft	YES
4397045	25874568	HKC	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397045	25874568	HKC	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397045	25874568	KS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397045	25874568	KS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397045	25874568	PT	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4397045	25874568	PT	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4397045	25874568	SHK	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4397045	25874568	SHK	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4397045	25874568	TJO	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4397045	25874568	TJO	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4987988	27531524	EK	PLoS52	performed the experiments|analysed the flow cytometry data	performed the experiments	Performed the experiments	Investigation	YES
4987988	27531524	EK	PLoS52	performed the experiments|analysed the flow cytometry data	analysed the flow cytometry data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4987988	27531524	EW	PLoS52	conceived of the study, and participated in its design and coordination|wrote the paper	conceived of the study, and participated in its design and coordination	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
4987988	27531524	EW	PLoS52	conceived of the study, and participated in its design and coordination|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4987988	27531524	MH	PLoS52	conceived of the study, and participated in its design and coordination|performed the experiments|analysed the flow cytometry data|performed the analysis of the deep sequencing data|wrote the paper	conceived of the study, and participated in its design and coordination	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
4987988	27531524	MH	PLoS52	conceived of the study, and participated in its design and coordination|performed the experiments|analysed the flow cytometry data|performed the analysis of the deep sequencing data|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
4987988	27531524	MH	PLoS52	conceived of the study, and participated in its design and coordination|performed the experiments|analysed the flow cytometry data|performed the analysis of the deep sequencing data|wrote the paper	analysed the flow cytometry data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4987988	27531524	MH	PLoS52	conceived of the study, and participated in its design and coordination|performed the experiments|analysed the flow cytometry data|performed the analysis of the deep sequencing data|wrote the paper	performed the analysis of the deep sequencing data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4987988	27531524	MH	PLoS52	conceived of the study, and participated in its design and coordination|performed the experiments|analysed the flow cytometry data|performed the analysis of the deep sequencing data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4987988	27531524	RJL	PLoS52	conceived of the study, and participated in its design and coordination|wrote the paper	conceived of the study, and participated in its design and coordination	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
4987988	27531524	RJL	PLoS52	conceived of the study, and participated in its design and coordination|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6321237	30551617	A.D.S.	CRediT	Conceptualization|Formal analysis|Funding acquisition|Investigation|Methodology|Project administration|Visualization|Writing-original draft	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6321237	30551617	A.D.S.	CRediT	Conceptualization|Formal analysis|Funding acquisition|Investigation|Methodology|Project administration|Visualization|Writing-original draft	Formal analysis	Analyzed the data	Formal analysis	YES
6321237	30551617	A.D.S.	CRediT	Conceptualization|Formal analysis|Funding acquisition|Investigation|Methodology|Project administration|Visualization|Writing-original draft	Funding acquisition	-	Funding acquisition	YES
6321237	30551617	A.D.S.	CRediT	Conceptualization|Formal analysis|Funding acquisition|Investigation|Methodology|Project administration|Visualization|Writing-original draft	Investigation	Performed the experiments	Investigation	YES
6321237	30551617	A.D.S.	CRediT	Conceptualization|Formal analysis|Funding acquisition|Investigation|Methodology|Project administration|Visualization|Writing-original draft	Methodology	Performed the experiments	Methodology	YES
6321237	30551617	A.D.S.	CRediT	Conceptualization|Formal analysis|Funding acquisition|Investigation|Methodology|Project administration|Visualization|Writing-original draft	Project administration	-	Project administration	YES
6321237	30551617	A.D.S.	CRediT	Conceptualization|Formal analysis|Funding acquisition|Investigation|Methodology|Project administration|Visualization|Writing-original draft	Visualization	Analyzed the data	Visualization	YES
6321237	30551617	A.D.S.	CRediT	Conceptualization|Formal analysis|Funding acquisition|Investigation|Methodology|Project administration|Visualization|Writing-original draft	Writing-original draft	Wrote the paper	Writing - Original Draft	YES
6321237	30551617	G.M.	CRediT	Supervision|Writing-original draft	Supervision	-	Supervision	YES
6321237	30551617	G.M.	CRediT	Supervision|Writing-original draft	Writing-original draft	Wrote the paper	Writing - Original Draft	YES
6321237	30551617	L.A.	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
6321237	30551617	M.A.C.	CRediT	Methodology|Supervision|Writing-original draft	Methodology	Performed the experiments	Methodology	YES
6321237	30551617	M.A.C.	CRediT	Methodology|Supervision|Writing-original draft	Supervision	-	Supervision	YES
6321237	30551617	M.A.C.	CRediT	Methodology|Supervision|Writing-original draft	Writing-original draft	Wrote the paper	Writing - Original Draft	YES
6321237	30551617	M.N.	CRediT	Formal analysis|Investigation|Visualization	Formal analysis	Analyzed the data	Formal analysis	YES
6321237	30551617	M.N.	CRediT	Formal analysis|Investigation|Visualization	Investigation	Performed the experiments	Investigation	YES
6321237	30551617	M.N.	CRediT	Formal analysis|Investigation|Visualization	Visualization	Analyzed the data	Visualization	YES
6321237	30551617	P.P.	CRediT	Conceptualization|Formal analysis|Investigation|Methodology|Project administration|Writing-original draft	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6321237	30551617	P.P.	CRediT	Conceptualization|Formal analysis|Investigation|Methodology|Project administration|Writing-original draft	Formal analysis	Analyzed the data	Formal analysis	YES
6321237	30551617	P.P.	CRediT	Conceptualization|Formal analysis|Investigation|Methodology|Project administration|Writing-original draft	Investigation	Performed the experiments	Investigation	YES
6321237	30551617	P.P.	CRediT	Conceptualization|Formal analysis|Investigation|Methodology|Project administration|Writing-original draft	Methodology	Performed the experiments	Methodology	YES
6321237	30551617	P.P.	CRediT	Conceptualization|Formal analysis|Investigation|Methodology|Project administration|Writing-original draft	Project administration	-	Project administration	YES
6321237	30551617	P.P.	CRediT	Conceptualization|Formal analysis|Investigation|Methodology|Project administration|Writing-original draft	Writing-original draft	Wrote the paper	Writing - Original Draft	YES
6321237	30551617	S.D.G.	CRediT	Investigation|Methodology	Investigation	Performed the experiments	Investigation	YES
6321237	30551617	S.D.G.	CRediT	Investigation|Methodology	Methodology	Performed the experiments	Methodology	YES
6321237	30551617	S.G.	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
6321237	30551617	S.P.	CRediT	Conceptualization|Investigation|Methodology|Project administration|Writing-original draft	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6321237	30551617	S.P.	CRediT	Conceptualization|Investigation|Methodology|Project administration|Writing-original draft	Investigation	Performed the experiments	Investigation	YES
6321237	30551617	S.P.	CRediT	Conceptualization|Investigation|Methodology|Project administration|Writing-original draft	Methodology	Performed the experiments	Methodology	YES
6321237	30551617	S.P.	CRediT	Conceptualization|Investigation|Methodology|Project administration|Writing-original draft	Project administration	-	Project administration	YES
6321237	30551617	S.P.	CRediT	Conceptualization|Investigation|Methodology|Project administration|Writing-original draft	Writing-original draft	Wrote the paper	Writing - Original Draft	YES
4387947	25879036	Fang Cao	2	contributed equally to the study and are co-first authors	contributed equally to the study and are co-first authors	-	-	NO
4387947	25879036	Xitao Wang	2	contributed equally to the study and are co-first authors	contributed equally to the study and are co-first authors	-	-	NO
6195399	30515053	all authors	2	were included in all steps of preparing this article	were included in all steps of preparing this article	-	-	NO
4397046	25874887	AK	PLoS5	Revised the manuscript critically for important intellectual content	Revised the manuscript critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4397046	25874887	HM	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4397046	25874887	KF	PLoS5	Revised the manuscript critically for important intellectual content	Revised the manuscript critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4397046	25874887	KN	PLoS5	Revised the manuscript critically for important intellectual content	Revised the manuscript critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4397046	25874887	MS	PLoS5	Revised the manuscript critically for important intellectual content	Revised the manuscript critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4397046	25874887	S. Nakagara	PLoS5	Revised the manuscript critically for important intellectual content	Revised the manuscript critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4397046	25874887	S. Noma	PLoS5	Revised the manuscript critically for important intellectual content	Revised the manuscript critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4397046	25874887	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397046	25874887	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397046	25874887	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397046	25874887	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397046	25874887	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397046	25874887	YM	PLoS5	Revised the manuscript critically for important intellectual content	Revised the manuscript critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4397046	25874887	YN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397046	25874887	YN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397046	25874887	YN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397046	25874887	YN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397046	25874887	YN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3127812	21609445	Both authors	2	contributed equally to this manuscript	contributed equally to this manuscript	-	-	NO
5423274	28536584	All authors	2	revised, integrated, and approved the manuscript	revised, integrated, and approved the manuscript	Wrote the paper	Writing - Review & Editing	YES
5423274	28536584	EB	2	designed and supervised the research work, and obtained financial resources	designed and supervised the research work, and obtained financial resources	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Funding acquisition|Investigation|Methodology|Resources|Supervision	YES
5423274	28536584	LP	2	were responsible for phenotyping experiments	were responsible for phenotyping experiments	Performed the experiments	Investigation	YES
5423274	28536584	NN	2	was responsible for bioinformatics analysis	was responsible for bioinformatics analysis	-	Formal analysis	YES
5423274	28536584	PA	2	designed and supervised the research work, and obtained financial resources|were responsible for phenotyping experiments|drafted the manuscript	designed and supervised the research work, and obtained financial resources	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Funding acquisition|Investigation|Methodology|Resources|Supervision	YES
5423274	28536584	PA	2	designed and supervised the research work, and obtained financial resources|were responsible for phenotyping experiments|drafted the manuscript	were responsible for phenotyping experiments	Performed the experiments	Investigation	YES
5423274	28536584	PA	2	designed and supervised the research work, and obtained financial resources|were responsible for phenotyping experiments|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5423274	28536584	YW	2	was responsible for lab experiments and generation of molecular data	was responsible for lab experiments and generation of molecular data	Performed the experiments	Investigation	YES
6023337	29921773	A.S.	2	collected information	collected information	Performed the experiments	Investigation	YES
6023337	29921773	A.T.	2	collected information	collected information	Performed the experiments	Investigation	YES
6023337	29921773	H.K.	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6023337	29921773	K.K.	2	collected information	collected information	Performed the experiments	Investigation	YES
6023337	29921773	M.T.	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6023337	29921773	N.K.	2	collected information	collected information	Performed the experiments	Investigation	YES
6023337	29921773	S.T.	2	collected information	collected information	Performed the experiments	Investigation	YES
6023337	29921773	S.Y.	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6023337	29921773	T.S.	2	collected information	collected information	Performed the experiments	Investigation	YES
6023337	29921773	T.Y.	2	collected information	collected information	Performed the experiments	Investigation	YES
6195406	30515063	All authors	2	in this paper have contributed in all phases in its preparing	in this paper have contributed in all phases in its preparing	-	-	NO
4987991	27530340	KJ	2	prepared rna sequencing library and performed qrt pcr	prepared rna sequencing library and performed qrt pcr	Performed the experiments	Investigation	YES
4987991	27530340	SK	2	constructed the cody deletion strain, analyzed rna sequencing data and performed chip-qpcr, and was a major contributor in writing the manuscript	constructed the cody deletion strain, analyzed rna sequencing data and performed chip-qpcr, and was a major contributor in writing the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4987991	27530340	YC	2	conceived and designed the experiments, and contributed in writing the manuscript	conceived and designed the experiments, and contributed in writing the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
6195407	30515058	Ahmad Bishara	1	Data collection and entry, overall concept and design, statistical analysis	Data collection and entry, overall concept and design, statistical analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Data curation|Formal analysis|Investigation	YES
6195407	30515058	Asma Zaidan	1	Data collection and entry, overall concept and design, statistical analysis|Data interpretation and manuscript writing and drafting	Data collection and entry, overall concept and design, statistical analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Data curation|Formal analysis|Investigation	YES
6195407	30515058	Asma Zaidan	1	Data collection and entry, overall concept and design, statistical analysis|Data interpretation and manuscript writing and drafting	Data interpretation and manuscript writing and drafting	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6195407	30515058	Hassan Abduljabbar	1	Data collection and entry, overall concept and design, statistical analysis|Data interpretation and manuscript writing and drafting	Data collection and entry, overall concept and design, statistical analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Data curation|Formal analysis|Investigation	YES
6195407	30515058	Hassan Abduljabbar	1	Data collection and entry, overall concept and design, statistical analysis|Data interpretation and manuscript writing and drafting	Data interpretation and manuscript writing and drafting	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6195407	30515058	Muhab Hindi	1	Data collection and entry, overall concept and design, statistical analysis	Data collection and entry, overall concept and design, statistical analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Data curation|Formal analysis|Investigation	YES
6195407	30515058	Samar Alolayan	1	Data collection and entry, overall concept and design, statistical analysis	Data collection and entry, overall concept and design, statistical analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Data curation|Formal analysis|Investigation	YES
4397047	25875823	GC	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Critical revision of the manuscript for important intellectual content	Performed the experiments	Performed the experiments	Investigation	YES
4397047	25875823	GC	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Critical revision of the manuscript for important intellectual content	Analyzed the data	Analyzed the data	Formal analysis	YES
4397047	25875823	GC	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Critical revision of the manuscript for important intellectual content	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397047	25875823	GC	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Critical revision of the manuscript for important intellectual content	Critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4397047	25875823	HJL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Critical revision of the manuscript for important intellectual content	Performed the experiments	Performed the experiments	Investigation	YES
4397047	25875823	HJL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Critical revision of the manuscript for important intellectual content	Analyzed the data	Analyzed the data	Formal analysis	YES
4397047	25875823	HJL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Critical revision of the manuscript for important intellectual content	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397047	25875823	HJL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Critical revision of the manuscript for important intellectual content	Critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4397047	25875823	SEL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Critical revision of the manuscript for important intellectual content	Performed the experiments	Performed the experiments	Investigation	YES
4397047	25875823	SEL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Critical revision of the manuscript for important intellectual content	Analyzed the data	Analyzed the data	Formal analysis	YES
4397047	25875823	SEL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Critical revision of the manuscript for important intellectual content	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397047	25875823	SEL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Critical revision of the manuscript for important intellectual content	Critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4397047	25875823	SIH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Critical revision of the manuscript for important intellectual content	Performed the experiments	Performed the experiments	Investigation	YES
4397047	25875823	SIH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Critical revision of the manuscript for important intellectual content	Analyzed the data	Analyzed the data	Formal analysis	YES
4397047	25875823	SIH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Critical revision of the manuscript for important intellectual content	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397047	25875823	SIH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Critical revision of the manuscript for important intellectual content	Critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4397047	25875823	SJJ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Critical revision of the manuscript for important intellectual content	Performed the experiments	Performed the experiments	Investigation	YES
4397047	25875823	SJJ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Critical revision of the manuscript for important intellectual content	Analyzed the data	Analyzed the data	Formal analysis	YES
4397047	25875823	SJJ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Critical revision of the manuscript for important intellectual content	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397047	25875823	SJJ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Critical revision of the manuscript for important intellectual content	Critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4397047	25875823	SKH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Critical revision of the manuscript for important intellectual content	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397047	25875823	SKH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Critical revision of the manuscript for important intellectual content	Performed the experiments	Performed the experiments	Investigation	YES
4397047	25875823	SKH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Critical revision of the manuscript for important intellectual content	Analyzed the data	Analyzed the data	Formal analysis	YES
4397047	25875823	SKH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Critical revision of the manuscript for important intellectual content	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397047	25875823	SKH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Critical revision of the manuscript for important intellectual content	Critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4397047	25875823	SL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397047	25875823	SL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397047	25875823	SL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397047	25875823	SL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397047	25875823	SL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397047	25875823	SSB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Critical revision of the manuscript for important intellectual content	Performed the experiments	Performed the experiments	Investigation	YES
4397047	25875823	SSB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Critical revision of the manuscript for important intellectual content	Analyzed the data	Analyzed the data	Formal analysis	YES
4397047	25875823	SSB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Critical revision of the manuscript for important intellectual content	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397047	25875823	SSB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Critical revision of the manuscript for important intellectual content	Critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
3132158	21658210	AMI	2	proposed the design of the study, carried out the development of the sic system, designed the optimization process and drafted the manuscript|read and approved the final manuscript	proposed the design of the study, carried out the development of the sic system, designed the optimization process and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Writing - Original Draft	YES
3132158	21658210	AMI	2	proposed the design of the study, carried out the development of the sic system, designed the optimization process and drafted the manuscript|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
3132158	21658210	REEE	2	carried out all experimental works and performed the statistical analysis|read and approved the final manuscript	carried out all experimental works and performed the statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3132158	21658210	REEE	2	carried out all experimental works and performed the statistical analysis|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5006004	22487223	AMK	2	were involved in the processing and storage of laboratory specimens	were involved in the processing and storage of laboratory specimens	Performed the experiments	Investigation	YES
5006004	22487223	ANG	2	were involved in additional microbiological processing	were involved in additional microbiological processing	-	-	NO
5006004	22487223	All	2	authors were involved in reviewing the final manuscript	authors were involved in reviewing the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5006004	22487223	CCB	2	were involved in the design of the study|were involved in the processing and storage of laboratory specimens|extracted additional microbiological data|were involved in additional microbiological processing|authors were involved in reviewing the final manuscript	were involved in the design of the study	Conceived and designed the experiments	Methodology	YES
5006004	22487223	CCB	2	were involved in the design of the study|were involved in the processing and storage of laboratory specimens|extracted additional microbiological data|were involved in additional microbiological processing|authors were involved in reviewing the final manuscript	were involved in the processing and storage of laboratory specimens	Performed the experiments	Investigation	YES
5006004	22487223	CCB	2	were involved in the design of the study|were involved in the processing and storage of laboratory specimens|extracted additional microbiological data|were involved in additional microbiological processing|authors were involved in reviewing the final manuscript	extracted additional microbiological data	Performed the experiments	Investigation	YES
5006004	22487223	CCB	2	were involved in the design of the study|were involved in the processing and storage of laboratory specimens|extracted additional microbiological data|were involved in additional microbiological processing|authors were involved in reviewing the final manuscript	were involved in additional microbiological processing	-	-	NO
5006004	22487223	CCB	2	were involved in the design of the study|were involved in the processing and storage of laboratory specimens|extracted additional microbiological data|were involved in additional microbiological processing|authors were involved in reviewing the final manuscript	authors were involved in reviewing the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5006004	22487223	DED	2	were involved in the design of the study	were involved in the design of the study	Conceived and designed the experiments	Methodology	YES
5006004	22487223	HF	2	were involved in the processing and storage of laboratory specimens|extracted additional microbiological data	were involved in the processing and storage of laboratory specimens	Performed the experiments	Investigation	YES
5006004	22487223	HF	2	were involved in the processing and storage of laboratory specimens|extracted additional microbiological data	extracted additional microbiological data	Performed the experiments	Investigation	YES
5006004	22487223	IS	2	were involved in the design of the study	were involved in the design of the study	Conceived and designed the experiments	Methodology	YES
5006004	22487223	JK	2	were involved in the processing and storage of laboratory specimens|extracted additional microbiological data|were involved in additional microbiological processing	were involved in the processing and storage of laboratory specimens	Performed the experiments	Investigation	YES
5006004	22487223	JK	2	were involved in the processing and storage of laboratory specimens|extracted additional microbiological data|were involved in additional microbiological processing	extracted additional microbiological data	Performed the experiments	Investigation	YES
5006004	22487223	JK	2	were involved in the processing and storage of laboratory specimens|extracted additional microbiological data|were involved in additional microbiological processing	were involved in additional microbiological processing	-	-	NO
5006004	22487223	JRI	2	were involved in the design of the study	were involved in the design of the study	Conceived and designed the experiments	Methodology	YES
5006004	22487223	SARW	2	were involved in the design of the study	were involved in the design of the study	Conceived and designed the experiments	Methodology	YES
5006004	22487223	SJvH	2	were involved in the processing and storage of laboratory specimens|extracted additional microbiological data	were involved in the processing and storage of laboratory specimens	Performed the experiments	Investigation	YES
5006004	22487223	SJvH	2	were involved in the processing and storage of laboratory specimens|extracted additional microbiological data	extracted additional microbiological data	Performed the experiments	Investigation	YES
6321242	30513858	A.-M.F.-R.	2	designed the protocol of the study|executed and characterized liposome formulations|wrote the draft of the manuscript	designed the protocol of the study	Conceived and designed the experiments	Methodology	YES
6321242	30513858	A.-M.F.-R.	2	designed the protocol of the study|executed and characterized liposome formulations|wrote the draft of the manuscript	executed and characterized liposome formulations	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
6321242	30513858	A.-M.F.-R.	2	designed the protocol of the study|executed and characterized liposome formulations|wrote the draft of the manuscript	wrote the draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
6321242	30513858	A.M.R.	2	executed and characterized liposome formulations|wrote the draft of the manuscript	executed and characterized liposome formulations	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
6321242	30513858	A.M.R.	2	executed and characterized liposome formulations|wrote the draft of the manuscript	wrote the draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
6321242	30513858	All the authors	2	critically reviewed and approved the final version of the manuscript	critically reviewed and approved the final version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
6321242	30513858	F.M.	2	designed the protocol of the study|executed and characterized liposome formulations|wrote the draft of the manuscript	designed the protocol of the study	Conceived and designed the experiments	Methodology	YES
6321242	30513858	F.M.	2	designed the protocol of the study|executed and characterized liposome formulations|wrote the draft of the manuscript	executed and characterized liposome formulations	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
6321242	30513858	F.M.	2	designed the protocol of the study|executed and characterized liposome formulations|wrote the draft of the manuscript	wrote the draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
6321242	30513858	M.L.G.-R.	2	designed the protocol of the study|executed and characterized liposome formulations|wrote the draft of the manuscript	designed the protocol of the study	Conceived and designed the experiments	Methodology	YES
6321242	30513858	M.L.G.-R.	2	designed the protocol of the study|executed and characterized liposome formulations|wrote the draft of the manuscript	executed and characterized liposome formulations	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
6321242	30513858	M.L.G.-R.	2	designed the protocol of the study|executed and characterized liposome formulations|wrote the draft of the manuscript	wrote the draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
6321242	30513858	P.A.M.	2	wrote the draft of the manuscript	wrote the draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
6321249	30428559	C.C.	CRediT	Conceptualization|Funding acquisition|Investigation|Methodology|Project administration|Software|Supervision|Validation|Visualization|Writing--original draft|Writing--review and editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6321249	30428559	C.C.	CRediT	Conceptualization|Funding acquisition|Investigation|Methodology|Project administration|Software|Supervision|Validation|Visualization|Writing--original draft|Writing--review and editing	Funding acquisition	-	Funding acquisition	YES
6321249	30428559	C.C.	CRediT	Conceptualization|Funding acquisition|Investigation|Methodology|Project administration|Software|Supervision|Validation|Visualization|Writing--original draft|Writing--review and editing	Investigation	Performed the experiments	Investigation	YES
6321249	30428559	C.C.	CRediT	Conceptualization|Funding acquisition|Investigation|Methodology|Project administration|Software|Supervision|Validation|Visualization|Writing--original draft|Writing--review and editing	Methodology	Performed the experiments	Methodology	YES
6321249	30428559	C.C.	CRediT	Conceptualization|Funding acquisition|Investigation|Methodology|Project administration|Software|Supervision|Validation|Visualization|Writing--original draft|Writing--review and editing	Project administration	-	Project administration	YES
6321249	30428559	C.C.	CRediT	Conceptualization|Funding acquisition|Investigation|Methodology|Project administration|Software|Supervision|Validation|Visualization|Writing--original draft|Writing--review and editing	Software	Contributed reagents/materials/analysis tools	Software	YES
6321249	30428559	C.C.	CRediT	Conceptualization|Funding acquisition|Investigation|Methodology|Project administration|Software|Supervision|Validation|Visualization|Writing--original draft|Writing--review and editing	Supervision	-	Supervision	YES
6321249	30428559	C.C.	CRediT	Conceptualization|Funding acquisition|Investigation|Methodology|Project administration|Software|Supervision|Validation|Visualization|Writing--original draft|Writing--review and editing	Validation	Performed the experiments	Validation	YES
6321249	30428559	C.C.	CRediT	Conceptualization|Funding acquisition|Investigation|Methodology|Project administration|Software|Supervision|Validation|Visualization|Writing--original draft|Writing--review and editing	Visualization	Analyzed the data	Visualization	YES
6321249	30428559	C.C.	CRediT	Conceptualization|Funding acquisition|Investigation|Methodology|Project administration|Software|Supervision|Validation|Visualization|Writing--original draft|Writing--review and editing	Writing--original draft	Wrote the paper	Writing - Original Draft	YES
6321249	30428559	C.C.	CRediT	Conceptualization|Funding acquisition|Investigation|Methodology|Project administration|Software|Supervision|Validation|Visualization|Writing--original draft|Writing--review and editing	Writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6321249	30428559	D.L.	CRediT	Data curation|Investigation|Methodology|Software|Validation|Visualization|Writing--review and editing	Data curation	Analyzed the data	Data curation	YES
6321249	30428559	D.L.	CRediT	Data curation|Investigation|Methodology|Software|Validation|Visualization|Writing--review and editing	Investigation	Performed the experiments	Investigation	YES
6321249	30428559	D.L.	CRediT	Data curation|Investigation|Methodology|Software|Validation|Visualization|Writing--review and editing	Methodology	Performed the experiments	Methodology	YES
6321249	30428559	D.L.	CRediT	Data curation|Investigation|Methodology|Software|Validation|Visualization|Writing--review and editing	Software	Contributed reagents/materials/analysis tools	Software	YES
6321249	30428559	D.L.	CRediT	Data curation|Investigation|Methodology|Software|Validation|Visualization|Writing--review and editing	Validation	Performed the experiments	Validation	YES
6321249	30428559	D.L.	CRediT	Data curation|Investigation|Methodology|Software|Validation|Visualization|Writing--review and editing	Visualization	Analyzed the data	Visualization	YES
6321249	30428559	D.L.	CRediT	Data curation|Investigation|Methodology|Software|Validation|Visualization|Writing--review and editing	Writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
3132159	21702979	EDJ	2	performed antioxidant assays	performed antioxidant assays	Performed the experiments	Investigation	YES
3132159	21702979	MMF	2	performed antioxidant assays	performed antioxidant assays	Performed the experiments	Investigation	YES
3132159	21702979	MS	2	method, performed qualitative phenolics analysis, and contributed to the results interpretation	method, performed qualitative phenolics analysis, and contributed to the results interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3132159	21702979	NMMD	2	coordinated the study, participated in its design and contributed to drafting manuscript	coordinated the study, participated in its design and contributed to drafting manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft	YES
3132159	21702979	SSP	2	performed sample preparations and fractionation of plant material	performed sample preparations and fractionation of plant material	Performed the experiments	Investigation	YES
6195409	30515059	Each author	2	participated in each step of research and article writing|gave final approval for publishing	participated in each step of research and article writing	Wrote the paper	-	YES
6195409	30515059	Each author	2	participated in each step of research and article writing|gave final approval for publishing	gave final approval for publishing	-	-	NO
4987992	27530161	A-MG	2	carried out in vivo study, microarray validation and elisa cytokine assessment	carried out in vivo study, microarray validation and elisa cytokine assessment	Performed the experiments	Investigation|Validation	YES
4987992	27530161	AJ	2	carried out the microarray study	carried out the microarray study	Performed the experiments	Investigation	YES
4987992	27530161	All the authors	2	participated for the writing of the paper and agreed to the final variant of the manuscript	participated for the writing of the paper and agreed to the final variant of the manuscript	Wrote the paper	Writing - Original Draft	YES
4987992	27530161	CB	2	carried out the microarray study|performed microarray statistical analysis	carried out the microarray study	Performed the experiments	Investigation	YES
4987992	27530161	CB	2	carried out the microarray study|performed microarray statistical analysis	performed microarray statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4987992	27530161	D-EM	2	carried out in vivo study, microarray validation and elisa cytokine assessment	carried out in vivo study, microarray validation and elisa cytokine assessment	Performed the experiments	Investigation|Validation	YES
4987992	27530161	DG	2	carried out the microarray study	carried out the microarray study	Performed the experiments	Investigation	YES
4987992	27530161	GP	2	carried out in vivo study, microarray validation and elisa cytokine assessment	carried out in vivo study, microarray validation and elisa cytokine assessment	Performed the experiments	Investigation|Validation	YES
4987992	27530161	IB-N	2	performed microarray statistical analysis	performed microarray statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4987992	27530161	IT	2	carried out in vivo study, microarray validation and elisa cytokine assessment	carried out in vivo study, microarray validation and elisa cytokine assessment	Performed the experiments	Investigation|Validation	YES
4987992	27530161	RC-P	2	performed microarray statistical analysis	performed microarray statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4397050	25875532	DK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397050	25875532	DK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397050	25875532	DK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397050	25875532	DYN	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397050	25875532	DYN	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397050	25875532	HS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397050	25875532	HS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397050	25875532	JWL	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397050	25875532	JWL	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397050	25875532	JYC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397050	25875532	JYC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397050	25875532	JYC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397050	25875532	JYC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397050	25875532	KYY	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397050	25875532	MKK	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397050	25875532	MKK	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397050	25875532	MS	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397050	25875532	NS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397050	25875532	NS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397050	25875532	NS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397050	25875532	NS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397050	25875532	SC	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397050	25875532	SC	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397050	25875532	SHA	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397050	25875532	SHA	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397050	25875532	SJ	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397050	25875532	SJ	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397050	25875532	SKP	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397050	25875532	SKP	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397050	25875532	WH	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397050	25875532	WH	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5423294	28536581	GZ	2	designed and supervised the research project|read and approved the final manuscript	designed and supervised the research project	Conceived and designed the experiments	Methodology|Supervision	YES
5423294	28536581	GZ	2	designed and supervised the research project|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5423294	28536581	JK	2	revised and edited the manuscript and also provided advice on the experiment	revised and edited the manuscript and also provided advice on the experiment	Wrote the paper	Writing - Review & Editing	YES
5423294	28536581	SA	2	analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5423294	28536581	SF	2	revised and edited the manuscript and also provided advice on the experiment	revised and edited the manuscript and also provided advice on the experiment	Wrote the paper	Writing - Review & Editing	YES
5423294	28536581	SK	2	performed the experiments and collected the data|analyzed the data and wrote the manuscript	performed the experiments and collected the data	Performed the experiments	Investigation	YES
5423294	28536581	SK	2	performed the experiments and collected the data|analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5423294	28536581	SU	2	helped in data collection	helped in data collection	Performed the experiments	Investigation	YES
6023369	29890712	A.M.F.	2	were responsible for data collection and critical review of the manuscript	were responsible for data collection and critical review of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
6023369	29890712	B.T.K.	2	were responsible for the data entry and analysis|were responsible for data collection and critical review of the manuscript	were responsible for the data entry and analysis	Analyzed the data	Data curation|Formal analysis	YES
6023369	29890712	B.T.K.	2	were responsible for the data entry and analysis|were responsible for data collection and critical review of the manuscript	were responsible for data collection and critical review of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
6023369	29890712	C.M.A.	2	were responsible for data collection and critical review of the manuscript	were responsible for data collection and critical review of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
6023369	29890712	E.K.N.F.	2	were responsible for data collection and critical review of the manuscript	were responsible for data collection and critical review of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
6023369	29890712	F.K.F.Y.	2	were responsible for data collection and critical review of the manuscript	were responsible for data collection and critical review of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
6023369	29890712	R.C.N.	2	were responsible for the study conception and design|were responsible for the data entry and analysis	were responsible for the study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6023369	29890712	R.C.N.	2	were responsible for the study conception and design|were responsible for the data entry and analysis	were responsible for the data entry and analysis	Analyzed the data	Data curation|Formal analysis	YES
6023369	29890712	T.C.	2	were responsible for data collection and critical review of the manuscript	were responsible for data collection and critical review of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
6023369	29890712	T.N.	2	were responsible for data collection and critical review of the manuscript	were responsible for data collection and critical review of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
6023369	29890712	V.F.F.	2	were responsible for the study conception and design	were responsible for the study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4598387	26464612	Michael Maley	2	provided critical input into the data analysis and reviewed the subsequent drafts of the manuscript	provided critical input into the data analysis and reviewed the subsequent drafts of the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft|Writing - Review & Editing	YES
4598387	26464612	Ruchir Chavada	2	provided critical input into the data analysis and reviewed the subsequent drafts of the manuscript	provided critical input into the data analysis and reviewed the subsequent drafts of the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft|Writing - Review & Editing	YES
3133535	21672253	AK	2	participated in the design of the study and preparing the draft manuscript	participated in the design of the study and preparing the draft manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3133535	21672253	ID	2	participated in the study design, statistical analysis of the data and preparing the manuscript	participated in the study design, statistical analysis of the data and preparing the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3133535	21672253	MK	2	participated in stability testing and application of the method	participated in stability testing and application of the method	Performed the experiments	Investigation	YES
3133535	21672253	MM	2	carried out the optimization of chromatographic conditions and stability testing	carried out the optimization of chromatographic conditions and stability testing	Performed the experiments	Investigation	YES
4387967	25879025	Chunyan Wang	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
4387967	25879025	Haifeng Hou	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
4387967	25879025	Ying Dong	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
6321262	30373320	B.P.	CRediT	Methodology	Methodology	Performed the experiments	Methodology	YES
6321262	30373320	B.R.	CRediT	Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6321262	30373320	G.N.	CRediT	Investigation|Writing--original draft	Investigation	Performed the experiments	Investigation	YES
6321262	30373320	G.N.	CRediT	Investigation|Writing--original draft	Writing--original draft	Wrote the paper	Writing - Original Draft	YES
6321262	30373320	J.-E.S.	CRediT	Visualization	Visualization	Analyzed the data	Visualization	YES
6321262	30373320	J.C.	CRediT	Formal analysis	Formal analysis	Analyzed the data	Formal analysis	YES
6321262	30373320	L.S.	CRediT	Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6321262	30373320	S.L.	CRediT	Supervision	Supervision	-	Supervision	YES
6321262	30373320	T.K.	CRediT	Formal analysis	Formal analysis	Analyzed the data	Formal analysis	YES
6321262	30373320	Y.W.C.	CRediT	Validation	Validation	Performed the experiments	Validation	YES
4397052	25875290	JKW	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397052	25875290	JKW	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397052	25875290	JKW	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397052	25875290	WFT	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4397052	25875290	XJS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4397052	25875290	XJS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397052	25875290	XLW	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397052	25875290	XQL	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397052	25875290	XQL	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4397052	25875290	XQL	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
6195410	30515057	MS	1	Substantial contribution to analysis and interpretation of data|Critically revising the article for important intellectual content|Final approval of the version to be published	Substantial contribution to analysis and interpretation of data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6195410	30515057	MS	1	Substantial contribution to analysis and interpretation of data|Critically revising the article for important intellectual content|Final approval of the version to be published	Critically revising the article for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
6195410	30515057	MS	1	Substantial contribution to analysis and interpretation of data|Critically revising the article for important intellectual content|Final approval of the version to be published	Final approval of the version to be published	-	-	NO
6195410	30515057	RAG	1	Substantial contribution to acquisition of data|Substantial contribution to analysis and interpretation of data	Substantial contribution to acquisition of data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
6195410	30515057	RAG	1	Substantial contribution to acquisition of data|Substantial contribution to analysis and interpretation of data	Substantial contribution to analysis and interpretation of data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6195410	30515057	RF	1	Substantial contribution to conception and design|Substantial contribution to analysis and interpretation of data|Final approval of the version to be published	Substantial contribution to conception and design	Conceived and designed the experiments	Conceptualization	YES
6195410	30515057	RF	1	Substantial contribution to conception and design|Substantial contribution to analysis and interpretation of data|Final approval of the version to be published	Substantial contribution to analysis and interpretation of data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6195410	30515057	RF	1	Substantial contribution to conception and design|Substantial contribution to analysis and interpretation of data|Final approval of the version to be published	Final approval of the version to be published	-	-	NO
6195410	30515057	SRB	1	Drafting the article	Drafting the article	Wrote the paper	Writing - Original Draft	YES
3135496	21699688	EG	2	participated in the design of the proteasome activation study	participated in the design of the proteasome activation study	Conceived and designed the experiments	Methodology	YES
3135496	21699688	GS	2	carried out the determination of total phenolics and the measurement of radical scavenging activity	carried out the determination of total phenolics and the measurement of radical scavenging activity	Performed the experiments	Investigation	YES
3135496	21699688	IC	2	conceived of the study and its design and coordination of the scientific teams, carried out the antimicrobial tests and assisted to draft the manuscript	conceived of the study and its design and coordination of the scientific teams, carried out the antimicrobial tests and assisted to draft the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Project administration|Writing - Original Draft	YES
3135496	21699688	KG	2	carried out the chemical analysis-structure elucidation and drafted the manuscript	carried out the chemical analysis-structure elucidation and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3135496	21699688	NA	2	assisted to the chemical structure determination	assisted to the chemical structure determination	-	-	NO
3135496	21699688	NC	2	participated in the proteasome activation study	participated in the proteasome activation study	-	-	NO
3135496	21699688	SK	2	carried out the measurement of proteasome activation	carried out the measurement of proteasome activation	Performed the experiments	Investigation	YES
4988008	27530109	CLR	2	participated in the phylogenetic and molecular evolution analysis	participated in the phylogenetic and molecular evolution analysis	Performed the experiments	Investigation	YES
4988008	27530109	CMJ	2	assisted in pcr amplifications and sequencing	assisted in pcr amplifications and sequencing	Performed the experiments	Investigation	YES
4988008	27530109	GJR	2	assisted in pcr amplifications and sequencing	assisted in pcr amplifications and sequencing	Performed the experiments	Investigation	YES
4988008	27530109	PVH	2	carried out the gene annotation and molecular evolution analysis and drafted the manuscript	carried out the gene annotation and molecular evolution analysis and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Formal analysis|Investigation|Writing - Original Draft	YES
5423392	28536583	AF	PLoS52	conducted the experiments	conducted the experiments	Performed the experiments	Investigation	YES
5423392	28536583	All authors	PLoS52	have given approval to the final version of the manuscript	have given approval to the final version of the manuscript	-	-	NO
5423392	28536583	KB	PLoS52	designed the research|conducted the experiments|processed the data with|analyzed the data|wrote the manuscript with editorial	designed the research	Conceived and designed the experiments	Methodology	YES
5423392	28536583	KB	PLoS52	designed the research|conducted the experiments|processed the data with|analyzed the data|wrote the manuscript with editorial	conducted the experiments	Performed the experiments	Investigation	YES
5423392	28536583	KB	PLoS52	designed the research|conducted the experiments|processed the data with|analyzed the data|wrote the manuscript with editorial	processed the data with	Analyzed the data	Data curation	YES
5423392	28536583	KB	PLoS52	designed the research|conducted the experiments|processed the data with|analyzed the data|wrote the manuscript with editorial	analyzed the data	Analyzed the data	Formal analysis	YES
5423392	28536583	KB	PLoS52	designed the research|conducted the experiments|processed the data with|analyzed the data|wrote the manuscript with editorial	wrote the manuscript with editorial	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5423392	28536583	KH	PLoS52	conducted the experiments|helped with the processed the data with	conducted the experiments	Performed the experiments	Investigation	YES
5423392	28536583	KH	PLoS52	conducted the experiments|helped with the processed the data with	helped with the processed the data with	Analyzed the data	Data curation	YES
5423392	28536583	MK	PLoS52	designed the research|analyzed the data|helped with the wrote the manuscript with editorial	designed the research	Conceived and designed the experiments	Methodology	YES
5423392	28536583	MK	PLoS52	designed the research|analyzed the data|helped with the wrote the manuscript with editorial	analyzed the data	Analyzed the data	Formal analysis	YES
5423392	28536583	MK	PLoS52	designed the research|analyzed the data|helped with the wrote the manuscript with editorial	helped with the wrote the manuscript with editorial	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5423392	28536583	MR	PLoS52	designed the research|helped with the wrote the manuscript with editorial	designed the research	Conceived and designed the experiments	Methodology	YES
5423392	28536583	MR	PLoS52	designed the research|helped with the wrote the manuscript with editorial	helped with the wrote the manuscript with editorial	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5423392	28536583	OP	PLoS52	designed the research|conducted the experiments|helped with the processed the data with|analyzed the data|helped with the wrote the manuscript with editorial	designed the research	Conceived and designed the experiments	Methodology	YES
5423392	28536583	OP	PLoS52	designed the research|conducted the experiments|helped with the processed the data with|analyzed the data|helped with the wrote the manuscript with editorial	conducted the experiments	Performed the experiments	Investigation	YES
5423392	28536583	OP	PLoS52	designed the research|conducted the experiments|helped with the processed the data with|analyzed the data|helped with the wrote the manuscript with editorial	helped with the processed the data with	Analyzed the data	Data curation	YES
5423392	28536583	OP	PLoS52	designed the research|conducted the experiments|helped with the processed the data with|analyzed the data|helped with the wrote the manuscript with editorial	analyzed the data	Analyzed the data	Formal analysis	YES
5423392	28536583	OP	PLoS52	designed the research|conducted the experiments|helped with the processed the data with|analyzed the data|helped with the wrote the manuscript with editorial	helped with the wrote the manuscript with editorial	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5423392	28536583	PR	PLoS52	designed the research|helped with the wrote the manuscript with editorial	designed the research	Conceived and designed the experiments	Methodology	YES
5423392	28536583	PR	PLoS52	designed the research|helped with the wrote the manuscript with editorial	helped with the wrote the manuscript with editorial	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5423392	28536583	VS	PLoS52	conducted the experiments	conducted the experiments	Performed the experiments	Investigation	YES
6195413	30515061	Each author	2	participated in each step of research|gave final approval for final version of article	participated in each step of research	-	-	NO
6195413	30515061	Each author	2	participated in each step of research|gave final approval for final version of article	gave final approval for final version of article	-	-	NO
6195413	30515061	G.R.	2	revised it critically	revised it critically	Wrote the paper	Writing - Review & Editing	YES
6321264	30360549	C.H.K.	2	carried out all experiments and measurements and participated in the draft writing	carried out all experiments and measurements and participated in the draft writing	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6321264	30360549	D.Y.K.	2	performed biological sample analysis	performed biological sample analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6321264	30360549	E.S.L.	2	performed the cell-associated experiments and assisted the animal experiments	performed the cell-associated experiments and assisted the animal experiments	Performed the experiments	Investigation	YES
6321264	30360549	H.R.C.	2	performed biological sample analysis	performed biological sample analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6321264	30360549	H.Y.Y.	2	carried out the protein adsorption and drug release studies	carried out the protein adsorption and drug release studies	Performed the experiments	Investigation	YES
6321264	30360549	M.J.K.	2	performed biological sample analysis	performed biological sample analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6321264	30360549	S.L.	2	assisted cytotoxicity and hemolysis measurements	assisted cytotoxicity and hemolysis measurements	Performed the experiments	Investigation	YES
6321264	30360549	S.W.S.	2	carried out all experiments and measurements and participated in the draft writing	carried out all experiments and measurements and participated in the draft writing	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6321264	30360549	T.H.K.	2	performed the cell-associated experiments and assisted the animal experiments	performed the cell-associated experiments and assisted the animal experiments	Performed the experiments	Investigation	YES
6321264	30360549	Y.S.C.	2	performed biological sample analysis	performed biological sample analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6321264	30360549	Y.T.G.	2	carried out the protein adsorption and drug release studies	carried out the protein adsorption and drug release studies	Performed the experiments	Investigation	YES
6321264	30360549	Y.W.C.	2	carried out all experiments and measurements and participated in the draft writing|was responsible for paper supervision and writing	carried out all experiments and measurements and participated in the draft writing	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6321264	30360549	Y.W.C.	2	carried out all experiments and measurements and participated in the draft writing|was responsible for paper supervision and writing	was responsible for paper supervision and writing	Wrote the paper	Supervision	YES
4397054	25875593	AP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397054	25875593	AP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397054	25875593	AP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397054	25875593	AP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397054	25875593	AP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397054	25875593	JL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397054	25875593	JL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397054	25875593	JL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3141621	21679411	CK	2	carried out under his guidance and consultation	carried out under his guidance and consultation	Performed the experiments	Investigation|Supervision	YES
3141621	21679411	CKs	2	research group	research group	-	-	NO
3141621	21679411	PG	2	was involved in xrd analysis and preparation of the manuscript	was involved in xrd analysis and preparation of the manuscript	Wrote the paper	Writing - Original Draft	YES
5423406	28536598	EK	2	have made substantial, direct and intellectual contributions to the work, and approved it for publication	have made substantial, direct and intellectual contributions to the work, and approved it for publication	-	-	NO
5423406	28536598	MJ	2	have made substantial, direct and intellectual contributions to the work, and approved it for publication	have made substantial, direct and intellectual contributions to the work, and approved it for publication	-	-	NO
6023392	29865237	B.S.	2	helped to collect and summarize published literature about the topic	helped to collect and summarize published literature about the topic	-	Formal analysis	YES
6023392	29865237	D.M.	2	wrote the manuscript|helped to collect and summarize published literature about the topic	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6023392	29865237	D.M.	2	wrote the manuscript|helped to collect and summarize published literature about the topic	helped to collect and summarize published literature about the topic	-	Formal analysis	YES
6023392	29865237	F.B.	2	wrote the manuscript|helped to collect and summarize published literature about the topic|contributed to planning the structure of the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6023392	29865237	F.B.	2	wrote the manuscript|helped to collect and summarize published literature about the topic|contributed to planning the structure of the manuscript	helped to collect and summarize published literature about the topic	-	Formal analysis	YES
6023392	29865237	F.B.	2	wrote the manuscript|helped to collect and summarize published literature about the topic|contributed to planning the structure of the manuscript	contributed to planning the structure of the manuscript	Conceived and designed the experiments	Methodology	YES
6023392	29865237	H.B.T.	2	contributed to planning the structure of the manuscript	contributed to planning the structure of the manuscript	Conceived and designed the experiments	Methodology	YES
6321266	30551686	A.P.S.	2	were responsible for the in vitro studies	were responsible for the in vitro studies	Performed the experiments	Investigation	YES
6321266	30551686	All authors	2	contributed for the manuscript preparation	contributed for the manuscript preparation	Wrote the paper	Writing - Original Draft	YES
6321266	30551686	B.S.G.V.	2	conceived the experiments	conceived the experiments	Conceived and designed the experiments	Conceptualization	YES
6321266	30551686	E.C.G.	2	performed the nail studies	performed the nail studies	Performed the experiments	Investigation	YES
6321266	30551686	F.J.O.-E.	2	designed and supervised the experiments	designed and supervised the experiments	Conceived and designed the experiments	Methodology|Supervision	YES
6321266	30551686	H.M.R.	2	designed and supervised the experiments	designed and supervised the experiments	Conceived and designed the experiments	Methodology|Supervision	YES
6321266	30551686	J.M.	2	was responsible for the antifungal experiments	was responsible for the antifungal experiments	Performed the experiments	Investigation	YES
6321266	30551686	J.M.B.	2	designed and supervised the experiments	designed and supervised the experiments	Conceived and designed the experiments	Methodology|Supervision	YES
6321266	30551686	R.G.d.S.	2	were responsible for the in vitro studies	were responsible for the in vitro studies	Performed the experiments	Investigation	YES
4988056	27530250	LL	2	conceived the study and wrote the manuscript	conceived the study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4988056	27530250	QT	2	performed the data analysis|conceived the study and wrote the manuscript	performed the data analysis	Analyzed the data	Formal analysis	YES
4988056	27530250	QT	2	performed the data analysis|conceived the study and wrote the manuscript	conceived the study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4397059	25875835	AG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397059	25875835	AG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397059	25875835	AG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397059	25875835	AG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397059	25875835	AU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397059	25875835	AU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397059	25875835	AU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397059	25875835	AU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397059	25875835	EW	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397059	25875835	EW	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397059	25875835	HB	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397059	25875835	HB	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397059	25875835	HP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397059	25875835	HP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397059	25875835	HP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397059	25875835	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397059	25875835	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397059	25875835	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397059	25875835	KF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397059	25875835	KF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397059	25875835	KF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397059	25875835	KF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397059	25875835	KG	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397059	25875835	KG	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397059	25875835	KG	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397059	25875835	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397059	25875835	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397059	25875835	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397059	25875835	MW	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397059	25875835	MW	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397059	25875835	RE	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397059	25875835	RE	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397059	25875835	ZEK	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397059	25875835	ZEK	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6234652	30429686	DP	2	contributed the conception and design of the study, collected data and carried out statistical analysis, prepared the manuscript, approved the paper to be submitted	contributed the conception and design of the study, collected data and carried out statistical analysis, prepared the manuscript, approved the paper to be submitted	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
6234652	30429686	DZ	2	contributed the conception and design of the study, critically revised the paper, approved the paper to be submitted	contributed the conception and design of the study, critically revised the paper, approved the paper to be submitted	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
6234652	30429686	GK	2	critically revised the paper, final approval of the version to be submitted	critically revised the paper, final approval of the version to be submitted	Wrote the paper	Writing - Review & Editing	YES
6234652	30429686	KK	2	contributed the conception and design of the study, approved the paper to be submitted	contributed the conception and design of the study, approved the paper to be submitted	Conceived and designed the experiments	Conceptualization|Methodology	YES
6234652	30429686	PE	2	contributed the conception and design of the study, critically revised the paper, approved the paper to be submitted	contributed the conception and design of the study, critically revised the paper, approved the paper to be submitted	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
3141622	21711563	FFB	2	proposed, planned and supervised the whole work	proposed, planned and supervised the whole work	Conceived and designed the experiments	Conceptualization|Supervision	YES
3141622	21711563	MHE	2	carried out the experimental work	carried out the experimental work	Performed the experiments	Investigation	YES
3141622	21711563	MIW	2	designed the proposed method and analyzed the data statistically	designed the proposed method and analyzed the data statistically	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
3141622	21711563	NME	2	coordinated the study and modified the text	coordinated the study and modified the text	-	Project administration	YES
6321274	30347876	D.H.H.	2	carried out all the experiments, designed all the studies, oversaw all experiments and contributed to draft the manuscript and intellectually to the development of the project	carried out all the experiments, designed all the studies, oversaw all experiments and contributed to draft the manuscript and intellectually to the development of the project	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Supervision|Writing - Original Draft	YES
6321274	30347876	M.M.A.	2	carried out all the experiments, designed all the studies, oversaw all experiments and contributed to draft the manuscript and intellectually to the development of the project	carried out all the experiments, designed all the studies, oversaw all experiments and contributed to draft the manuscript and intellectually to the development of the project	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Supervision|Writing - Original Draft	YES
6321274	30347876	R.A.	2	carried out all the experiments, designed all the studies, oversaw all experiments and contributed to draft the manuscript and intellectually to the development of the project	carried out all the experiments, designed all the studies, oversaw all experiments and contributed to draft the manuscript and intellectually to the development of the project	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Supervision|Writing - Original Draft	YES
6023396	29614023	E.A.D.	2	contributed to data collection	contributed to data collection	Performed the experiments	Investigation	YES
6023396	29614023	E.G.V.	2	contributed to the analysis and interpretation of data, drafting the article	contributed to the analysis and interpretation of data, drafting the article	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
6023396	29614023	E.P.A.	2	contributed to data collection	contributed to data collection	Performed the experiments	Investigation	YES
6023396	29614023	I.S.M.M.	2	contributed to the conception and design of the work	contributed to the conception and design of the work	Conceived and designed the experiments	Conceptualization	YES
6023396	29614023	J.A.B.O.	2	contributed to the conception and design of the work	contributed to the conception and design of the work	Conceived and designed the experiments	Conceptualization	YES
6023396	29614023	L.C.Y.	2	critically revised the article	critically revised the article	Wrote the paper	Writing - Review & Editing	YES
6023396	29614023	M.J.C.C.	2	critically revised the article	critically revised the article	Wrote the paper	Writing - Review & Editing	YES
5766454	29354381	ANT	2	revised manuscript in english and performed elisa	revised manuscript in english and performed elisa	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5766454	29354381	BG	2	performed microinjection and controlled animals	performed microinjection and controlled animals	Performed the experiments	Investigation	YES
5766454	29354381	DL	2	designed the study and wrote the manuscript|analyzed data	designed the study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5766454	29354381	DL	2	designed the study and wrote the manuscript|analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5766454	29354381	JJ	2	performed microinjection and controlled animals	performed microinjection and controlled animals	Performed the experiments	Investigation	YES
5766454	29354381	JZ	2	designed the study and wrote the manuscript|performed cas9/grna mutation screening and sequencing	designed the study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5766454	29354381	JZ	2	designed the study and wrote the manuscript|performed cas9/grna mutation screening and sequencing	performed cas9/grna mutation screening and sequencing	Performed the experiments	Investigation	YES
5766454	29354381	MH	2	performed cas9/grna mutation screening and sequencing|performed the nk assay	performed cas9/grna mutation screening and sequencing	Performed the experiments	Investigation	YES
5766454	29354381	MH	2	performed cas9/grna mutation screening and sequencing|performed the nk assay	performed the nk assay	Performed the experiments	Investigation	YES
5766454	29354381	RS	2	was the group supervisor	was the group supervisor	-	Supervision	YES
5766454	29354381	ZS	2	performed microinjection and controlled animals	performed microinjection and controlled animals	Performed the experiments	Investigation	YES
5423411	28536593	All authors	2	have read and approved the final manuscript	have read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5423411	28536593	DZ	2	carried out the experiments and drafted the manuscript	carried out the experiments and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5423411	28536593	SS	2	carried out the experiments and drafted the manuscript	carried out the experiments and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5423411	28536593	XL	2	participated in the study and helped to draft the manuscript	participated in the study and helped to draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5423411	28536593	YH	2	participated in the study and helped to draft the manuscript	participated in the study and helped to draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5423411	28536593	YY	2	conceived the study, planned experiments, and helped draft the manuscript	conceived the study, planned experiments, and helped draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
6234653	30429687	Aida Cengic	1	Collection of data, data processing, writing the article	Collection of data, data processing, writing the article	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Investigation|Writing - Original Draft	YES
6234653	30429687	Amira Skopljak	1	Collection of data, data processing, writing the article	Collection of data, data processing, writing the article	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Investigation|Writing - Original Draft	YES
6234653	30429687	Belma Gazibera	1	Collection of data, data processing, writing the article	Collection of data, data processing, writing the article	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Investigation|Writing - Original Draft	YES
6234653	30429687	Belma Kapo	1	Collection of data, data processing, writing the article	Collection of data, data processing, writing the article	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Investigation|Writing - Original Draft	YES
6234653	30429687	Ilhana Setic-Avdagic	1	Collection of data, data processing, writing the article	Collection of data, data processing, writing the article	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Investigation|Writing - Original Draft	YES
6234653	30429687	Mersiha Becirovic	1	Collection of data, data processing, writing the article	Collection of data, data processing, writing the article	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Investigation|Writing - Original Draft	YES
6234653	30429687	Refet Gojak	1	Collection of data, data processing, writing the article	Collection of data, data processing, writing the article	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Investigation|Writing - Original Draft	YES
6234653	30429687	Slobodan M. Jankovic	1	Design of the study, data processing, writing the article	Design of the study, data processing, writing the article	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Data curation|Methodology|Writing - Original Draft	YES
6234653	30429687	Tarik Catic	1	Collection of data, data processing, writing the article	Collection of data, data processing, writing the article	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Investigation|Writing - Original Draft	YES
6234653	30429687	Vildana Zelihic	1	Collection of data, data processing, writing the article	Collection of data, data processing, writing the article	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Investigation|Writing - Original Draft	YES
6234653	30429687	Zumreta Pintol	1	Collection of data, data processing, writing the article	Collection of data, data processing, writing the article	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Investigation|Writing - Original Draft	YES
3149563	21682931	AD	2	participated in the sample collection and the preparation of the plant extracts	participated in the sample collection and the preparation of the plant extracts	Performed the experiments	Investigation	YES
3149563	21682931	BKN	2	participated in the study design and coordination of study	participated in the study design and coordination of study	Conceived and designed the experiments	Methodology|Project administration	YES
3149563	21682931	CYO	2	performed the photo-cytotoxicity testing of 128 extracts|contributed to the drafting of the manuscript	performed the photo-cytotoxicity testing of 128 extracts	Performed the experiments	Investigation	YES
3149563	21682931	CYO	2	performed the photo-cytotoxicity testing of 128 extracts|contributed to the drafting of the manuscript	contributed to the drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
3149563	21682931	HBL	2	participated in the study design and coordination of study|contributed to the drafting of the manuscript	participated in the study design and coordination of study	Conceived and designed the experiments	Methodology|Project administration	YES
3149563	21682931	HBL	2	participated in the study design and coordination of study|contributed to the drafting of the manuscript	contributed to the drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
3149563	21682931	HMY	2	participated in the sample collection and the preparation of the plant extracts	participated in the sample collection and the preparation of the plant extracts	Performed the experiments	Investigation	YES
3149563	21682931	PJT	2	was involved in the isolation, purification and identification of compound 1|contributed to the drafting of the manuscript	was involved in the isolation, purification and identification of compound 1	Performed the experiments	Investigation	YES
3149563	21682931	PJT	2	was involved in the isolation, purification and identification of compound 1|contributed to the drafting of the manuscript	contributed to the drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
4397061	25875205	DKM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4397061	25875205	DKM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397061	25875205	DRB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397061	25875205	DRB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397061	25875205	DRB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397061	25875205	DRB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397061	25875205	DRB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397061	25875205	HM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397061	25875205	HM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397061	25875205	HM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397061	25875205	HM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397061	25875205	HM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397061	25875205	JHH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4397061	25875205	KMS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397061	25875205	KMS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397061	25875205	KMS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397061	25875205	KMS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397061	25875205	MF	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4397061	25875205	MF	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4397061	25875205	MP	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397061	25875205	MP	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4397061	25875205	RPD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397061	25875205	RPD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397061	25875205	RPD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397061	25875205	RPD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397061	25875205	RPD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397061	25875205	TKL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4397061	25875205	TKL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397061	25875205	WL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397061	25875205	WSL	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4397061	25875205	WSL	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
6321278	30304840	A.M.C.	2	curated the data	curated the data	Analyzed the data	Data curation	YES
6321278	30304840	C.L.	2	provided cells and took part in the design of the in vitro experiments	provided cells and took part in the design of the in vitro experiments	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources	YES
6321278	30304840	G.D.R.	2	provided funding and coordinated the formulation study	provided funding and coordinated the formulation study	Conceived and designed the experiments	Conceptualization|Funding acquisition|Project administration	YES
6321278	30304840	L.M.	2	prepared the original draft and reviewed the paper	prepared the original draft and reviewed the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6321278	30304840	M.A.	2	curated the data	curated the data	Analyzed the data	Data curation	YES
6321278	30304840	M.C.	2	provided funding and coordinated the study on cell culture	provided funding and coordinated the study on cell culture	Performed the experiments|Contributed reagents/materials/analysis tools	Funding acquisition|Investigation|Project administration|Resources	YES
6321278	30304840	M.P.	2	provided cells and took part in the design of the in vitro experiments	provided cells and took part in the design of the in vitro experiments	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources	YES
6321278	30304840	S.G.	2	arranged and performed the experiments, prepared the original draft	arranged and performed the experiments, prepared the original draft	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6321278	30304840	S.Z.	2	arranged and performed the experiments, prepared the original draft	arranged and performed the experiments, prepared the original draft	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6321278	30304840	V.C.	2	curated the data	curated the data	Analyzed the data	Data curation	YES
6023457	29614774	G.V.	2	read, amended and approved the final version of the manuscript	read, amended and approved the final version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
6023457	29614774	L.V.	2	conception and design of commentary/limited review|read, amended and approved the final version of the manuscript	conception and design of commentary/limited review	Conceived and designed the experiments	Conceptualization	YES
6023457	29614774	L.V.	2	conception and design of commentary/limited review|read, amended and approved the final version of the manuscript	read, amended and approved the final version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
6023457	29614774	S.H.	2	read, amended and approved the final version of the manuscript	read, amended and approved the final version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4989286	27535741	AM	1	Manuscript writing and figures	Manuscript writing and figures	Wrote the paper	Visualization|Writing - Original Draft	YES
4989286	27535741	AT	1	Tissue collection, trimming, and pathology	Tissue collection, trimming, and pathology	Performed the experiments	Investigation	YES
4989286	27535741	CF	1	Experimental concept and design, sample selection|Manuscript writing and figures	Experimental concept and design, sample selection	Conceived and designed the experiments	Conceptualization|Methodology	YES
4989286	27535741	CF	1	Experimental concept and design, sample selection|Manuscript writing and figures	Manuscript writing and figures	Wrote the paper	Visualization|Writing - Original Draft	YES
4989286	27535741	EK	1	Experimental concept and design, sample selection|Sequencing alignment and mirna enrichment analysis|Manuscript writing and figures	Experimental concept and design, sample selection	Conceived and designed the experiments	Conceptualization|Methodology	YES
4989286	27535741	EK	1	Experimental concept and design, sample selection|Sequencing alignment and mirna enrichment analysis|Manuscript writing and figures	Sequencing alignment and mirna enrichment analysis	Performed the experiments	Investigation	YES
4989286	27535741	EK	1	Experimental concept and design, sample selection|Sequencing alignment and mirna enrichment analysis|Manuscript writing and figures	Manuscript writing and figures	Wrote the paper	Visualization|Writing - Original Draft	YES
4989286	27535741	FW	1	Manuscript writing and figures	Manuscript writing and figures	Wrote the paper	Visualization|Writing - Original Draft	YES
4989286	27535741	HB	1	Manuscript writing and figures	Manuscript writing and figures	Wrote the paper	Visualization|Writing - Original Draft	YES
4989286	27535741	JG	1	Sequencing alignment and mirna enrichment analysis	Sequencing alignment and mirna enrichment analysis	Performed the experiments	Investigation	YES
4989286	27535741	MC	1	Experimental concept and design, sample selection|Tissue collection, trimming, and pathology	Experimental concept and design, sample selection	Conceived and designed the experiments	Conceptualization|Methodology	YES
4989286	27535741	MC	1	Experimental concept and design, sample selection|Tissue collection, trimming, and pathology	Tissue collection, trimming, and pathology	Performed the experiments	Investigation	YES
4989286	27535741	MG	1	Tissue collection, trimming, and pathology	Tissue collection, trimming, and pathology	Performed the experiments	Investigation	YES
4989286	27535741	PK	1	Experimental concept and design, sample selection|Manuscript writing and figures	Experimental concept and design, sample selection	Conceived and designed the experiments	Conceptualization|Methodology	YES
4989286	27535741	PK	1	Experimental concept and design, sample selection|Manuscript writing and figures	Manuscript writing and figures	Wrote the paper	Visualization|Writing - Original Draft	YES
4989286	27535741	RP	1	Tissue collection, trimming, and pathology	Tissue collection, trimming, and pathology	Performed the experiments	Investigation	YES
4989286	27535741	ST	1	Tissue collection, trimming, and pathology	Tissue collection, trimming, and pathology	Performed the experiments	Investigation	YES
3149564	21726466	AA	2	participated in preparation of protein conjugates and discussion of the results	participated in preparation of protein conjugates and discussion of the results	Performed the experiments	Investigation	YES
3149564	21726466	HA	2	prepared the antibody and conducted the assay development	prepared the antibody and conducted the assay development	Performed the experiments	Investigation	YES
3149564	21726466	ID	2	designed the study and supervised ha in conducting all the experiments, discussed the results and prepared the manuscript	designed the study and supervised ha in conducting all the experiments, discussed the results and prepared the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Supervision|Writing - Original Draft	YES
6321298	30562958	A.K.M.	CRediT	methodology|formal analysis|resources|data curation|writing--original draft preparation|writing--review and editing	methodology	Performed the experiments	Methodology	YES
6321298	30562958	A.K.M.	CRediT	methodology|formal analysis|resources|data curation|writing--original draft preparation|writing--review and editing	formal analysis	Analyzed the data	Formal analysis	YES
6321298	30562958	A.K.M.	CRediT	methodology|formal analysis|resources|data curation|writing--original draft preparation|writing--review and editing	resources	Contributed reagents/materials/analysis tools	Resources	YES
6321298	30562958	A.K.M.	CRediT	methodology|formal analysis|resources|data curation|writing--original draft preparation|writing--review and editing	data curation	Analyzed the data	Data curation	YES
6321298	30562958	A.K.M.	CRediT	methodology|formal analysis|resources|data curation|writing--original draft preparation|writing--review and editing	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6321298	30562958	A.K.M.	CRediT	methodology|formal analysis|resources|data curation|writing--original draft preparation|writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6321298	30562958	A.P.	CRediT	Conceptualization|resources|data curation|writing--original draft preparation|writing--review and editing|supervision|project administration|funding acquisition	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6321298	30562958	A.P.	CRediT	Conceptualization|resources|data curation|writing--original draft preparation|writing--review and editing|supervision|project administration|funding acquisition	resources	Contributed reagents/materials/analysis tools	Resources	YES
6321298	30562958	A.P.	CRediT	Conceptualization|resources|data curation|writing--original draft preparation|writing--review and editing|supervision|project administration|funding acquisition	data curation	Analyzed the data	Data curation	YES
6321298	30562958	A.P.	CRediT	Conceptualization|resources|data curation|writing--original draft preparation|writing--review and editing|supervision|project administration|funding acquisition	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6321298	30562958	A.P.	CRediT	Conceptualization|resources|data curation|writing--original draft preparation|writing--review and editing|supervision|project administration|funding acquisition	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6321298	30562958	A.P.	CRediT	Conceptualization|resources|data curation|writing--original draft preparation|writing--review and editing|supervision|project administration|funding acquisition	supervision	-	Supervision	YES
6321298	30562958	A.P.	CRediT	Conceptualization|resources|data curation|writing--original draft preparation|writing--review and editing|supervision|project administration|funding acquisition	project administration	-	Project administration	YES
6321298	30562958	A.P.	CRediT	Conceptualization|resources|data curation|writing--original draft preparation|writing--review and editing|supervision|project administration|funding acquisition	funding acquisition	-	Funding acquisition	YES
6321298	30562958	J.M.M.	CRediT	Conceptualization|resources|data curation|writing--original draft preparation|writing--review and editing|supervision|project administration|funding acquisition	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6321298	30562958	J.M.M.	CRediT	Conceptualization|resources|data curation|writing--original draft preparation|writing--review and editing|supervision|project administration|funding acquisition	resources	Contributed reagents/materials/analysis tools	Resources	YES
6321298	30562958	J.M.M.	CRediT	Conceptualization|resources|data curation|writing--original draft preparation|writing--review and editing|supervision|project administration|funding acquisition	data curation	Analyzed the data	Data curation	YES
6321298	30562958	J.M.M.	CRediT	Conceptualization|resources|data curation|writing--original draft preparation|writing--review and editing|supervision|project administration|funding acquisition	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6321298	30562958	J.M.M.	CRediT	Conceptualization|resources|data curation|writing--original draft preparation|writing--review and editing|supervision|project administration|funding acquisition	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6321298	30562958	J.M.M.	CRediT	Conceptualization|resources|data curation|writing--original draft preparation|writing--review and editing|supervision|project administration|funding acquisition	supervision	-	Supervision	YES
6321298	30562958	J.M.M.	CRediT	Conceptualization|resources|data curation|writing--original draft preparation|writing--review and editing|supervision|project administration|funding acquisition	project administration	-	Project administration	YES
6321298	30562958	J.M.M.	CRediT	Conceptualization|resources|data curation|writing--original draft preparation|writing--review and editing|supervision|project administration|funding acquisition	funding acquisition	-	Funding acquisition	YES
6321298	30562958	K.Y.W.	CRediT	formal analysis|resources|data curation|writing--review and editing	formal analysis	Analyzed the data	Formal analysis	YES
6321298	30562958	K.Y.W.	CRediT	formal analysis|resources|data curation|writing--review and editing	resources	Contributed reagents/materials/analysis tools	Resources	YES
6321298	30562958	K.Y.W.	CRediT	formal analysis|resources|data curation|writing--review and editing	data curation	Analyzed the data	Data curation	YES
6321298	30562958	K.Y.W.	CRediT	formal analysis|resources|data curation|writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6321298	30562958	L.J.J.	CRediT	methodology|formal analysis|resources|data curation|writing--review and editing	methodology	Performed the experiments	Methodology	YES
6321298	30562958	L.J.J.	CRediT	methodology|formal analysis|resources|data curation|writing--review and editing	formal analysis	Analyzed the data	Formal analysis	YES
6321298	30562958	L.J.J.	CRediT	methodology|formal analysis|resources|data curation|writing--review and editing	resources	Contributed reagents/materials/analysis tools	Resources	YES
6321298	30562958	L.J.J.	CRediT	methodology|formal analysis|resources|data curation|writing--review and editing	data curation	Analyzed the data	Data curation	YES
6321298	30562958	L.J.J.	CRediT	methodology|formal analysis|resources|data curation|writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6321298	30562958	M.D.-S.	CRediT	methodology|formal analysis|resources|data curation|writing--review and editing	methodology	Performed the experiments	Methodology	YES
6321298	30562958	M.D.-S.	CRediT	methodology|formal analysis|resources|data curation|writing--review and editing	formal analysis	Analyzed the data	Formal analysis	YES
6321298	30562958	M.D.-S.	CRediT	methodology|formal analysis|resources|data curation|writing--review and editing	resources	Contributed reagents/materials/analysis tools	Resources	YES
6321298	30562958	M.D.-S.	CRediT	methodology|formal analysis|resources|data curation|writing--review and editing	data curation	Analyzed the data	Data curation	YES
6321298	30562958	M.D.-S.	CRediT	methodology|formal analysis|resources|data curation|writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6321298	30562958	N.P.	CRediT	formal analysis|resources|data curation|writing--review and editing	formal analysis	Analyzed the data	Formal analysis	YES
6321298	30562958	N.P.	CRediT	formal analysis|resources|data curation|writing--review and editing	resources	Contributed reagents/materials/analysis tools	Resources	YES
6321298	30562958	N.P.	CRediT	formal analysis|resources|data curation|writing--review and editing	data curation	Analyzed the data	Data curation	YES
6321298	30562958	N.P.	CRediT	formal analysis|resources|data curation|writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6321298	30562958	T.K.	CRediT	formal analysis|resources|data curation|writing--review and editing	formal analysis	Analyzed the data	Formal analysis	YES
6321298	30562958	T.K.	CRediT	formal analysis|resources|data curation|writing--review and editing	resources	Contributed reagents/materials/analysis tools	Resources	YES
6321298	30562958	T.K.	CRediT	formal analysis|resources|data curation|writing--review and editing	data curation	Analyzed the data	Data curation	YES
6321298	30562958	T.K.	CRediT	formal analysis|resources|data curation|writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6265597	30515052	The author	2	contributed in all steps of the preparation of this paper	contributed in all steps of the preparation of this paper	-	-	NO
3150235	21722377	GC	2	has formulated the research idea and prepared the manuscript draft version	has formulated the research idea and prepared the manuscript draft version	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
3150235	21722377	QS	2	carried out the chemical and biological studies	carried out the chemical and biological studies	Performed the experiments	Investigation	YES
3150235	21722377	SM	2	carried out the chemical and biological studies	carried out the chemical and biological studies	Performed the experiments	Investigation	YES
3150235	21722377	XH	2	conceived of the study, participated in its design and coordination	conceived of the study, participated in its design and coordination	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
3150235	21722377	YW	2	prepared the manuscript for submission and coordinated further formalities	prepared the manuscript for submission and coordinated further formalities	Wrote the paper	Project administration|Writing - Original Draft	YES
5801106	29430376	BCK	2	contributed to the experimental design and writing of the manuscript	contributed to the experimental design and writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5801106	29430376	CKK	2	designed and conducted the experiments and wrote the manuscript	designed and conducted the experiments and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5801106	29430376	DSK	2	contributed to the experimental design and writing of the manuscript	contributed to the experimental design and writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5801106	29430376	EJB	2	contributed to the experimental design and writing of the manuscript	contributed to the experimental design and writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5801106	29430376	JHO	2	conducted the experiments and wrote the manuscript	conducted the experiments and wrote the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5801106	29430376	YJL	2	contributed to the experimental design and writing of the manuscript	contributed to the experimental design and writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5423897	28539931	AA	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5423897	28539931	EA	2	conceived the study|designed and coordinated the experiments|wrote the manuscript|revised the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5423897	28539931	EA	2	conceived the study|designed and coordinated the experiments|wrote the manuscript|revised the manuscript	designed and coordinated the experiments	Conceived and designed the experiments	Methodology|Project administration	YES
5423897	28539931	EA	2	conceived the study|designed and coordinated the experiments|wrote the manuscript|revised the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5423897	28539931	EA	2	conceived the study|designed and coordinated the experiments|wrote the manuscript|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5423897	28539931	FV	2	conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5423897	28539931	GM	2	performed the lab experiments|revised the manuscript	performed the lab experiments	Performed the experiments	Investigation	YES
5423897	28539931	GM	2	performed the lab experiments|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5423897	28539931	HL	2	wrote the manuscript|revised the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5423897	28539931	HL	2	wrote the manuscript|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5423897	28539931	IC	2	wrote the manuscript|revised the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5423897	28539931	IC	2	wrote the manuscript|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5423897	28539931	IR	2	chose and provided the germplasm|provided the historical and anthropological information	chose and provided the germplasm	-	-	NO
5423897	28539931	IR	2	chose and provided the germplasm|provided the historical and anthropological information	provided the historical and anthropological information	-	-	NO
5423897	28539931	LC	2	chose and provided the germplasm	chose and provided the germplasm	-	-	NO
5423897	28539931	LR	2	conducted the ssr data analysis|wrote the manuscript|revised the manuscript	conducted the ssr data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5423897	28539931	LR	2	conducted the ssr data analysis|wrote the manuscript|revised the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5423897	28539931	LR	2	conducted the ssr data analysis|wrote the manuscript|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5423897	28539931	MG	2	chose and provided the germplasm	chose and provided the germplasm	-	-	NO
5423897	28539931	NF	2	performed the lab experiments|conducted the ssr data analysis|wrote the manuscript|revised the manuscript	performed the lab experiments	Performed the experiments	Investigation	YES
5423897	28539931	NF	2	performed the lab experiments|conducted the ssr data analysis|wrote the manuscript|revised the manuscript	conducted the ssr data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5423897	28539931	NF	2	performed the lab experiments|conducted the ssr data analysis|wrote the manuscript|revised the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5423897	28539931	NF	2	performed the lab experiments|conducted the ssr data analysis|wrote the manuscript|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5423897	28539931	RT	2	conducted the ssr data analysis|wrote the manuscript|revised the manuscript	conducted the ssr data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5423897	28539931	RT	2	conducted the ssr data analysis|wrote the manuscript|revised the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5423897	28539931	RT	2	conducted the ssr data analysis|wrote the manuscript|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4397062	25875107	BX	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397062	25875107	CW	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4397062	25875107	CW	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397062	25875107	CZ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397062	25875107	LX	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397062	25875107	LX	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397062	25875107	LX	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397062	25875107	LY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397062	25875107	LY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397062	25875107	LY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397062	25875107	LY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397062	25875107	PHG	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397062	25875107	TL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397062	25875107	XQ	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4397062	25875107	XQ	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397062	25875107	XY	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397062	25875107	XY	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397062	25875107	YC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4397062	25875107	ZL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
6377919	30936794	E.B.	2	gave substantial contribution to the conception or design of the work and in the acquisition, analysis and interpretation of data for the work	gave substantial contribution to the conception or design of the work and in the acquisition, analysis and interpretation of data for the work	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
6377919	30936794	Each author	2	had role in drafting the work and revising it critically for important intellectual content|gave final approval of the version to be published and they are agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	had role in drafting the work and revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6377919	30936794	Each author	2	had role in drafting the work and revising it critically for important intellectual content|gave final approval of the version to be published and they are agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	gave final approval of the version to be published and they are agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	-	-	NO
6377919	30936794	N.S.	2	gave substantial contribution to the conception or design of the work and in the acquisition, analysis and interpretation of data for the work	gave substantial contribution to the conception or design of the work and in the acquisition, analysis and interpretation of data for the work	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
4989532	27538507	CLG	2	collected almost all samples and participated in some experiments	collected almost all samples and participated in some experiments	Performed the experiments	Investigation	YES
4989532	27538507	JT	2	designed and conceived of the study	designed and conceived of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4989532	27538507	MMC	2	participated in all experiments	participated in all experiments	Performed the experiments	Investigation	YES
4989532	27538507	PFL	2	designed and conceived of the study|also helped to draft the manuscript	designed and conceived of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4989532	27538507	PFL	2	designed and conceived of the study|also helped to draft the manuscript	also helped to draft the manuscript	Wrote the paper	Writing - Original Draft	YES
4989532	27538507	PH	2	carried out the molecular genetic studies, performed the sequence alignment, experiments and drafted the manuscript	carried out the molecular genetic studies, performed the sequence alignment, experiments and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4989532	27538507	YQL	2	designed and conceived of the study|also helped to draft the manuscript	designed and conceived of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4989532	27538507	YQL	2	designed and conceived of the study|also helped to draft the manuscript	also helped to draft the manuscript	Wrote the paper	Writing - Original Draft	YES
6321319	30400577	G.A.S.A.	CRediT	Conceptualization|resources|writing--review and editing|funding acquisition	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6321319	30400577	G.A.S.A.	CRediT	Conceptualization|resources|writing--review and editing|funding acquisition	resources	Contributed reagents/materials/analysis tools	Resources	YES
6321319	30400577	G.A.S.A.	CRediT	Conceptualization|resources|writing--review and editing|funding acquisition	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6321319	30400577	G.A.S.A.	CRediT	Conceptualization|resources|writing--review and editing|funding acquisition	funding acquisition	-	Funding acquisition	YES
6321319	30400577	G.F.P.	CRediT	resources|funding acquisition	resources	Contributed reagents/materials/analysis tools	Resources	YES
6321319	30400577	G.F.P.	CRediT	resources|funding acquisition	funding acquisition	-	Funding acquisition	YES
6321319	30400577	G.M.E.-Z.	CRediT	methodology|formal analysis|investigation	methodology	Performed the experiments	Methodology	YES
6321319	30400577	G.M.E.-Z.	CRediT	methodology|formal analysis|investigation	formal analysis	Analyzed the data	Formal analysis	YES
6321319	30400577	G.M.E.-Z.	CRediT	methodology|formal analysis|investigation	investigation	Performed the experiments	Investigation	YES
6321319	30400577	L.C.	CRediT	Conceptualization|methodology|formal analysis|investigation|resources|writing--original draft preparation|writing--review and editing|funding acquisition	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6321319	30400577	L.C.	CRediT	Conceptualization|methodology|formal analysis|investigation|resources|writing--original draft preparation|writing--review and editing|funding acquisition	methodology	Performed the experiments	Methodology	YES
6321319	30400577	L.C.	CRediT	Conceptualization|methodology|formal analysis|investigation|resources|writing--original draft preparation|writing--review and editing|funding acquisition	formal analysis	Analyzed the data	Formal analysis	YES
6321319	30400577	L.C.	CRediT	Conceptualization|methodology|formal analysis|investigation|resources|writing--original draft preparation|writing--review and editing|funding acquisition	investigation	Performed the experiments	Investigation	YES
6321319	30400577	L.C.	CRediT	Conceptualization|methodology|formal analysis|investigation|resources|writing--original draft preparation|writing--review and editing|funding acquisition	resources	Contributed reagents/materials/analysis tools	Resources	YES
6321319	30400577	L.C.	CRediT	Conceptualization|methodology|formal analysis|investigation|resources|writing--original draft preparation|writing--review and editing|funding acquisition	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6321319	30400577	L.C.	CRediT	Conceptualization|methodology|formal analysis|investigation|resources|writing--original draft preparation|writing--review and editing|funding acquisition	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6321319	30400577	L.C.	CRediT	Conceptualization|methodology|formal analysis|investigation|resources|writing--original draft preparation|writing--review and editing|funding acquisition	funding acquisition	-	Funding acquisition	YES
6321319	30400577	L.I.	CRediT	writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6321319	30400577	M.C.	CRediT	methodology|formal analysis|investigation|writing--original draft preparation	methodology	Performed the experiments	Methodology	YES
6321319	30400577	M.C.	CRediT	methodology|formal analysis|investigation|writing--original draft preparation	formal analysis	Analyzed the data	Formal analysis	YES
6321319	30400577	M.C.	CRediT	methodology|formal analysis|investigation|writing--original draft preparation	investigation	Performed the experiments	Investigation	YES
6321319	30400577	M.C.	CRediT	methodology|formal analysis|investigation|writing--original draft preparation	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6321319	30400577	M.E.S.	CRediT	Conceptualization|methodology|formal analysis|investigation|writing--original draft preparation|writing--review and editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6321319	30400577	M.E.S.	CRediT	Conceptualization|methodology|formal analysis|investigation|writing--original draft preparation|writing--review and editing	methodology	Performed the experiments	Methodology	YES
6321319	30400577	M.E.S.	CRediT	Conceptualization|methodology|formal analysis|investigation|writing--original draft preparation|writing--review and editing	formal analysis	Analyzed the data	Formal analysis	YES
6321319	30400577	M.E.S.	CRediT	Conceptualization|methodology|formal analysis|investigation|writing--original draft preparation|writing--review and editing	investigation	Performed the experiments	Investigation	YES
6321319	30400577	M.E.S.	CRediT	Conceptualization|methodology|formal analysis|investigation|writing--original draft preparation|writing--review and editing	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6321319	30400577	M.E.S.	CRediT	Conceptualization|methodology|formal analysis|investigation|writing--original draft preparation|writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6321319	30400577	S.M.	CRediT	formal analysis|investigation|writing--original draft preparation	formal analysis	Analyzed the data	Formal analysis	YES
6321319	30400577	S.M.	CRediT	formal analysis|investigation|writing--original draft preparation	investigation	Performed the experiments	Investigation	YES
6321319	30400577	S.M.	CRediT	formal analysis|investigation|writing--original draft preparation	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
3154853	21762499	AHPH	2	participated in impedance and xafs data measurements, respectively	participated in impedance and xafs data measurements, respectively	Performed the experiments	Investigation	YES
3154853	21762499	MH	2	performed the sample preparation and nitrogen analysis	performed the sample preparation and nitrogen analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3154853	21762499	ML	2	performed the sample preparation and nitrogen analysis	performed the sample preparation and nitrogen analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3154853	21762499	PSZ	2	participated in impedance and xafs data measurements, respectively	participated in impedance and xafs data measurements, respectively	Performed the experiments	Investigation	YES
3154853	21762499	SK	2	participated in sample characterization and data analysis, and drafted the manuscript	participated in sample characterization and data analysis, and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3154853	21762499	TR	2	participated in sample characterization and data analysis, and design and coordination of the study	participated in sample characterization and data analysis, and design and coordination of the study	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology|Project administration	YES
6023471	29677098	A.J.D.	2	contributed and analyzed the long-term follow-up data	contributed and analyzed the long-term follow-up data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6023471	29677098	H.H.	2	conceived and wrote the paper|contributed and analyzed the long-term follow-up data	conceived and wrote the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
6023471	29677098	H.H.	2	conceived and wrote the paper|contributed and analyzed the long-term follow-up data	contributed and analyzed the long-term follow-up data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6023471	29677098	J.Y.	2	conceived and wrote the paper	conceived and wrote the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
6023471	29677098	M.C.	2	contributed and analyzed the long-term follow-up data	contributed and analyzed the long-term follow-up data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6023471	29677098	R.C.	2	contributed and analyzed the long-term follow-up data	contributed and analyzed the long-term follow-up data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5423900	28539934	C-FY	2	designed the study|analyzed the results and wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5423900	28539934	C-FY	2	designed the study|analyzed the results and wrote the manuscript	analyzed the results and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5423900	28539934	GA	2	analyzed the results and wrote the manuscript	analyzed the results and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5423900	28539934	Q-FW	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5423900	28539934	X-FJ	2	designed the study|carried out the fieldwork|analyzed the results and wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5423900	28539934	X-FJ	2	designed the study|carried out the fieldwork|analyzed the results and wrote the manuscript	carried out the fieldwork	Performed the experiments	Investigation	YES
5423900	28539934	X-FJ	2	designed the study|carried out the fieldwork|analyzed the results and wrote the manuscript	analyzed the results and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5423900	28539934	Z-MY	2	carried out the fieldwork|analyzed the results and wrote the manuscript	carried out the fieldwork	Performed the experiments	Investigation	YES
5423900	28539934	Z-MY	2	carried out the fieldwork|analyzed the results and wrote the manuscript	analyzed the results and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6377920	30936786	A.D.N.	2	had role in drafting the work and revising it critically for important intellectual content	had role in drafting the work and revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6377920	30936786	E.J.	2	had role in drafting the work and revising it critically for important intellectual content	had role in drafting the work and revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6377920	30936786	Each author	2	gave final approval of the version to be published and they are agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	gave final approval of the version to be published and they are agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	-	-	NO
6377920	30936786	F.Z.	2	had role in drafting the work and revising it critically for important intellectual content	had role in drafting the work and revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6377920	30936786	J.H.	2	gave substantial contribution to the conception or design of the work and in the acquisition, analysis and interpretation of data for the work	gave substantial contribution to the conception or design of the work and in the acquisition, analysis and interpretation of data for the work	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
6377920	30936786	M.V.	2	gave substantial contribution to the conception or design of the work and in the acquisition, analysis and interpretation of data for the work	gave substantial contribution to the conception or design of the work and in the acquisition, analysis and interpretation of data for the work	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
6377920	30936786	N.R.	2	had role in drafting the work and revising it critically for important intellectual content	had role in drafting the work and revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4397063	25875648	GV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the software used in analysis	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397063	25875648	GV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the software used in analysis	Analyzed the data	Analyzed the data	Formal analysis	YES
4397063	25875648	GV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the software used in analysis	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397063	25875648	GV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the software used in analysis	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397063	25875648	GV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the software used in analysis	Designed the software used in analysis	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
4397063	25875648	IMvdW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397063	25875648	IMvdW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397063	25875648	IMvdW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397063	25875648	IMvdW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397063	25875648	RFK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397063	25875648	RFK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397063	25875648	RFK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6023473	29751499	C.M.	2	followed the patients and collected clinical and laboratory data	followed the patients and collected clinical and laboratory data	Performed the experiments	Investigation	YES
6023473	29751499	E.M.	2	followed the patients and collected clinical and laboratory data	followed the patients and collected clinical and laboratory data	Performed the experiments	Investigation	YES
6023473	29751499	F.Z.	2	followed the patients and collected clinical and laboratory data	followed the patients and collected clinical and laboratory data	Performed the experiments	Investigation	YES
6023473	29751499	G.G.	2	contributed to planning the research and to the revision of the manuscript	contributed to planning the research and to the revision of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
6023473	29751499	G.M.	2	followed the patients and collected clinical and laboratory data	followed the patients and collected clinical and laboratory data	Performed the experiments	Investigation	YES
6023473	29751499	G.P.	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6023473	29751499	L.D.M.	2	contributed to the statistical analyses and to the revision of the manuscript	contributed to the statistical analyses and to the revision of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
6023473	29751499	M.G.	2	contributed to the statistical analyses and to the revision of the manuscript	contributed to the statistical analyses and to the revision of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
6023473	29751499	P.B.	2	contributed to planning the research and to the revision of the manuscript	contributed to planning the research and to the revision of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
6023473	29751499	V.G.	2	contributed to planning the research and to the revision of the manuscript	contributed to planning the research and to the revision of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
3155476	21777420	FC	2	index and drafted the manuscript	index and drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
3155476	21777420	MS	2	measurements, and conducted the final data analysis including statistics and drafted the manuscript	measurements, and conducted the final data analysis including statistics and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3155476	21777420	TK	2	revised the paper draft	revised the paper draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3155476	21777420	WS	2	revised the paper draft	revised the paper draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6321321	30308982	All authors	2	analyzed and discussed the results and reviewed the manuscript	analyzed and discussed the results and reviewed the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
6321321	30308982	H.O.	2	conducted in vitro cytotoxicity examinations and transcellular transport assays	conducted in vitro cytotoxicity examinations and transcellular transport assays	Performed the experiments	Investigation	YES
6321321	30308982	H.T.	2	conducted in situ loop absorption experiments|conducted in vivo oral absorption experiments|conducted in situ intestinal toxicity examinations	conducted in situ loop absorption experiments	Performed the experiments	Investigation	YES
6321321	30308982	H.T.	2	conducted in situ loop absorption experiments|conducted in vivo oral absorption experiments|conducted in situ intestinal toxicity examinations	conducted in vivo oral absorption experiments	Performed the experiments	Investigation	YES
6321321	30308982	H.T.	2	conducted in situ loop absorption experiments|conducted in vivo oral absorption experiments|conducted in situ intestinal toxicity examinations	conducted in situ intestinal toxicity examinations	Performed the experiments	Investigation	YES
6321321	30308982	K.H.	2	conducted in vivo oral absorption experiments	conducted in vivo oral absorption experiments	Performed the experiments	Investigation	YES
6321321	30308982	K.M.	2	conducted enzymatic degradation assays	conducted enzymatic degradation assays	Performed the experiments	Investigation	YES
6321321	30308982	M.M.	2	conducted in situ loop absorption experiments|conducted in vivo oral absorption experiments|conducted spr-binding assays	conducted in situ loop absorption experiments	Performed the experiments	Investigation	YES
6321321	30308982	M.M.	2	conducted in situ loop absorption experiments|conducted in vivo oral absorption experiments|conducted spr-binding assays	conducted in vivo oral absorption experiments	Performed the experiments	Investigation	YES
6321321	30308982	M.M.	2	conducted in situ loop absorption experiments|conducted in vivo oral absorption experiments|conducted spr-binding assays	conducted spr-binding assays	Performed the experiments	Investigation	YES
6321321	30308982	M.T.-M.	2	conceived the study and acquired research grants|designed the study	conceived the study and acquired research grants	Conceived and designed the experiments	Conceptualization	YES
6321321	30308982	M.T.-M.	2	conceived the study and acquired research grants|designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
6321321	30308982	N.K.	2	designed the study|prepared the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
6321321	30308982	N.K.	2	designed the study|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
6321321	30308982	S.H.	2	conducted in vitro cytotoxicity examinations and transcellular transport assays	conducted in vitro cytotoxicity examinations and transcellular transport assays	Performed the experiments	Investigation	YES
6321321	30308982	Y.H.	2	conducted enzymatic degradation assays	conducted enzymatic degradation assays	Performed the experiments	Investigation	YES
6377921	30936790	A.H.	2	gave substantial contribution to the conception or design of the work and in the acquisition, analysis and interpretation of data for the work, each author had role in drafting the work and revising it critically for important intellectual content	gave substantial contribution to the conception or design of the work and in the acquisition, analysis and interpretation of data for the work, each author had role in drafting the work and revising it critically for important intellectual content	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
6377921	30936790	E.S.	2	gave substantial contribution to the conception or design of the work and in the acquisition, analysis and interpretation of data for the work, each author had role in drafting the work and revising it critically for important intellectual content	gave substantial contribution to the conception or design of the work and in the acquisition, analysis and interpretation of data for the work, each author had role in drafting the work and revising it critically for important intellectual content	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
6377921	30936790	Each author	2	gave final approval of the version to be published and they are agreeing to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	gave final approval of the version to be published and they are agreeing to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	-	-	NO
3158111	21791053	JKS	5	collected the x-ray data and solved the crystal structures under the guidance of SN	collected the x-ray data and solved the crystal structures under the guidance of SN	Performed the experiments	Investigation|Supervision	YES
3158111	21791053	JS	5	synthesized the title compounds under the guidance of SP	synthesized the title compounds under the guidance of SP	Performed the experiments	Investigation|Supervision	YES
3158111	21791053	SMR	5	synthesized the title compounds under the guidance of SP	synthesized the title compounds under the guidance of SP	Performed the experiments	Investigation|Supervision	YES
4397064	25876027	AD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397064	25876027	AD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397064	25876027	AD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397064	25876027	CB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397064	25876027	CB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397064	25876027	CB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397064	25876027	CB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397064	25876027	CB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397064	25876027	EM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397064	25876027	EM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397064	25876027	EM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397064	25876027	KZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397064	25876027	KZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4397064	25876027	KZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5423904	28539932	B. Authors	2	equally contributed to the experimental designs	equally contributed to the experimental designs	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5423904	28539932	ES	2	conducted experiments under primary|critically reviewed the manuscript	conducted experiments under primary	Performed the experiments	Investigation	YES
5423904	28539932	ES	2	conducted experiments under primary|critically reviewed the manuscript	critically reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5423904	28539932	SB	2	supervised es conducted experiments under primary|who also critically reviewed the manuscript	supervised es conducted experiments under primary	Performed the experiments	Investigation|Supervision	YES
5423904	28539932	SB	2	supervised es conducted experiments under primary|who also critically reviewed the manuscript	who also critically reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5423904	28539932	VB	2	supervised es conducted experiments under primary|who also critically reviewed the manuscript	supervised es conducted experiments under primary	Performed the experiments	Investigation|Supervision	YES
5423904	28539932	VB	2	supervised es conducted experiments under primary|who also critically reviewed the manuscript	who also critically reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
6377922	30936785	All authors	2	gave substantial contribution to the acquisition, analysis, or interpretation of data for the work|had a part in article preparing for drafting or revising it critically for important intellectual content, and all authors gave final approval of the version to be published and agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	gave substantial contribution to the acquisition, analysis, or interpretation of data for the work	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
6377922	30936785	All authors	2	gave substantial contribution to the acquisition, analysis, or interpretation of data for the work|had a part in article preparing for drafting or revising it critically for important intellectual content, and all authors gave final approval of the version to be published and agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	had a part in article preparing for drafting or revising it critically for important intellectual content, and all authors gave final approval of the version to be published and agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6377922	30936785	KL	2	gave substantial contribution to the conception or design of the work	gave substantial contribution to the conception or design of the work	Conceived and designed the experiments	Conceptualization	YES
6377922	30936785	MI	2	gave substantial contribution to the conception or design of the work|gave substantial contribution of data	gave substantial contribution to the conception or design of the work	Conceived and designed the experiments	Conceptualization	YES
6377922	30936785	MI	2	gave substantial contribution to the conception or design of the work|gave substantial contribution of data	gave substantial contribution of data	Contributed reagents/materials/analysis tools	Resources	YES
6377922	30936785	PP	2	gave substantial contribution to the conception or design of the work	gave substantial contribution to the conception or design of the work	Conceived and designed the experiments	Conceptualization	YES
6377922	30936785	ST	2	gave substantial contribution to the conception or design of the work|gave substantial contribution of data	gave substantial contribution to the conception or design of the work	Conceived and designed the experiments	Conceptualization	YES
6377922	30936785	ST	2	gave substantial contribution to the conception or design of the work|gave substantial contribution of data	gave substantial contribution of data	Contributed reagents/materials/analysis tools	Resources	YES
6321337	30544534	A.L.-C.	CRediT	Conceptualization|funding acquisition|writing--review and editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6321337	30544534	A.L.-C.	CRediT	Conceptualization|funding acquisition|writing--review and editing	funding acquisition	-	Funding acquisition	YES
6321337	30544534	A.L.-C.	CRediT	Conceptualization|funding acquisition|writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6321337	30544534	C.B.-F.	CRediT	investigation	investigation	Performed the experiments	Investigation	YES
6321337	30544534	M.A.C.-P.	CRediT	Conceptualization|investigation|writing--original draft preparation	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6321337	30544534	M.A.C.-P.	CRediT	Conceptualization|investigation|writing--original draft preparation	investigation	Performed the experiments	Investigation	YES
6321337	30544534	M.A.C.-P.	CRediT	Conceptualization|investigation|writing--original draft preparation	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6321337	30544534	M.B.D.-C.	CRediT	Conceptualization|writing--review and editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6321337	30544534	M.B.D.-C.	CRediT	Conceptualization|writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6321337	30544534	M.S.-M.	CRediT	investigation	investigation	Performed the experiments	Investigation	YES
6321337	30544534	V.M.	CRediT	Conceptualization|writing--review and editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6321337	30544534	V.M.	CRediT	Conceptualization|writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6023479	29789451	All authors	2	contributed to the drafting of the paper and approved of the final manuscript	contributed to the drafting of the paper and approved of the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3159096	21801445	BS	2	is involved in the characterization of catalyst	is involved in the characterization of catalyst	Performed the experiments	Investigation	YES
3159096	21801445	MS	2	conceived of the study and participated in its design and coordination	conceived of the study and participated in its design and coordination	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
3159096	21801445	RV	2	carried out all the experiments used in this study	carried out all the experiments used in this study	Performed the experiments	Investigation	YES
4989536	27535656	All coauthors	2	were involved in study design and data interpretation	were involved in study design and data interpretation	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
4989536	27535656	CLA	2	conceived of the study|collected a	conceived of the study	Conceived and designed the experiments	Conceptualization	YES
4989536	27535656	CLA	2	conceived of the study|collected a	collected a	Performed the experiments	Investigation	YES
4989536	27535656	PC	2	conceived of the study|helped to generate rna seq data	conceived of the study	Conceived and designed the experiments	Conceptualization	YES
4989536	27535656	PC	2	conceived of the study|helped to generate rna seq data	helped to generate rna seq data	Performed the experiments	Investigation	YES
4397065	25875282	FM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397065	25875282	FM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397065	25875282	FM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397065	25875282	FM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397065	25875282	HM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397065	25875282	HM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397065	25875282	HM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397065	25875282	HM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397065	25875282	HM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397065	25875282	MF	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397065	25875282	MF	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397065	25875282	TM	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397065	25875282	TM	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397065	25875282	TT	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397065	25875282	TT	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6377923	30936788	Each author	2	gave final approval of the version to be published and they are agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	gave final approval of the version to be published and they are agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	-	-	NO
6377923	30936788	S.P.	2	gave substantial contribution to the conception or design of the work and in the acquisition, analysis and interpretation of data for the work|had role in drafting the work and revising it critically for important intellectual content	gave substantial contribution to the conception or design of the work and in the acquisition, analysis and interpretation of data for the work	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
6377923	30936788	S.P.	2	gave substantial contribution to the conception or design of the work and in the acquisition, analysis and interpretation of data for the work|had role in drafting the work and revising it critically for important intellectual content	had role in drafting the work and revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6023489	29652794	All authors	2	reviewed the final the manuscript and made important intellectual contributions to the final version	reviewed the final the manuscript and made important intellectual contributions to the final version	Wrote the paper	Writing - Review & Editing	YES
6023489	29652794	D.S.	2	analyzed the acoustic data|performed the statistical analysis	analyzed the acoustic data	Analyzed the data	Formal analysis	YES
6023489	29652794	D.S.	2	analyzed the acoustic data|performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
6023489	29652794	I.A.	2	collected the phonocardiographic and hemodynamic data and reviewed and analyzed the clinical data|performed the cardiac catheterizations|wrote the first draft of the manuscript	collected the phonocardiographic and hemodynamic data and reviewed and analyzed the clinical data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6023489	29652794	I.A.	2	collected the phonocardiographic and hemodynamic data and reviewed and analyzed the clinical data|performed the cardiac catheterizations|wrote the first draft of the manuscript	performed the cardiac catheterizations	Performed the experiments	Investigation	YES
6023489	29652794	I.A.	2	collected the phonocardiographic and hemodynamic data and reviewed and analyzed the clinical data|performed the cardiac catheterizations|wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
6023489	29652794	J.R.	2	collected the phonocardiographic and hemodynamic data and reviewed and analyzed the clinical data|collected the phonocardiographic and hemodynamic data and reviewed and analyzed the clinical data|collected the phonocardiographic and hemodynamic data and reviewed and analyzed the clinical data|performed the cardiac catheterizations	collected the phonocardiographic and hemodynamic data and reviewed and analyzed the clinical data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6023489	29652794	J.R.	2	collected the phonocardiographic and hemodynamic data and reviewed and analyzed the clinical data|collected the phonocardiographic and hemodynamic data and reviewed and analyzed the clinical data|collected the phonocardiographic and hemodynamic data and reviewed and analyzed the clinical data|performed the cardiac catheterizations	collected the phonocardiographic and hemodynamic data and reviewed and analyzed the clinical data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6023489	29652794	J.R.	2	collected the phonocardiographic and hemodynamic data and reviewed and analyzed the clinical data|collected the phonocardiographic and hemodynamic data and reviewed and analyzed the clinical data|collected the phonocardiographic and hemodynamic data and reviewed and analyzed the clinical data|performed the cardiac catheterizations	collected the phonocardiographic and hemodynamic data and reviewed and analyzed the clinical data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6023489	29652794	J.R.	2	collected the phonocardiographic and hemodynamic data and reviewed and analyzed the clinical data|collected the phonocardiographic and hemodynamic data and reviewed and analyzed the clinical data|collected the phonocardiographic and hemodynamic data and reviewed and analyzed the clinical data|performed the cardiac catheterizations	performed the cardiac catheterizations	Performed the experiments	Investigation	YES
6023489	29652794	L.G.	2	collected the phonocardiographic and hemodynamic data and reviewed and analyzed the clinical data|collected the phonocardiographic and hemodynamic data and reviewed and analyzed the clinical data	collected the phonocardiographic and hemodynamic data and reviewed and analyzed the clinical data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6023489	29652794	L.G.	2	collected the phonocardiographic and hemodynamic data and reviewed and analyzed the clinical data|collected the phonocardiographic and hemodynamic data and reviewed and analyzed the clinical data	collected the phonocardiographic and hemodynamic data and reviewed and analyzed the clinical data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6023489	29652794	M.E.	2	collected the phonocardiographic and hemodynamic data and reviewed and analyzed the clinical data|analyzed the acoustic data|wrote the first draft of the manuscript|prepared the figures|performed the statistical analysis	collected the phonocardiographic and hemodynamic data and reviewed and analyzed the clinical data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6023489	29652794	M.E.	2	collected the phonocardiographic and hemodynamic data and reviewed and analyzed the clinical data|analyzed the acoustic data|wrote the first draft of the manuscript|prepared the figures|performed the statistical analysis	analyzed the acoustic data	Analyzed the data	Formal analysis	YES
6023489	29652794	M.E.	2	collected the phonocardiographic and hemodynamic data and reviewed and analyzed the clinical data|analyzed the acoustic data|wrote the first draft of the manuscript|prepared the figures|performed the statistical analysis	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
6023489	29652794	M.E.	2	collected the phonocardiographic and hemodynamic data and reviewed and analyzed the clinical data|analyzed the acoustic data|wrote the first draft of the manuscript|prepared the figures|performed the statistical analysis	prepared the figures	-	Visualization	YES
6023489	29652794	M.E.	2	collected the phonocardiographic and hemodynamic data and reviewed and analyzed the clinical data|analyzed the acoustic data|wrote the first draft of the manuscript|prepared the figures|performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
6023489	29652794	P.B.	2	collected the phonocardiographic and hemodynamic data and reviewed and analyzed the clinical data|collected the phonocardiographic and hemodynamic data and reviewed and analyzed the clinical data	collected the phonocardiographic and hemodynamic data and reviewed and analyzed the clinical data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6023489	29652794	P.B.	2	collected the phonocardiographic and hemodynamic data and reviewed and analyzed the clinical data|collected the phonocardiographic and hemodynamic data and reviewed and analyzed the clinical data	collected the phonocardiographic and hemodynamic data and reviewed and analyzed the clinical data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6023489	29652794	R.Z.	2	analyzed the acoustic data	analyzed the acoustic data	Analyzed the data	Formal analysis	YES
6023489	29652794	S.J.	2	collected the phonocardiographic and hemodynamic data and reviewed and analyzed the clinical data	collected the phonocardiographic and hemodynamic data and reviewed and analyzed the clinical data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6023489	29652794	Y.C.	2	collected the phonocardiographic and hemodynamic data and reviewed and analyzed the clinical data|performed the cardiac catheterizations	collected the phonocardiographic and hemodynamic data and reviewed and analyzed the clinical data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6023489	29652794	Y.C.	2	collected the phonocardiographic and hemodynamic data and reviewed and analyzed the clinical data|performed the cardiac catheterizations	performed the cardiac catheterizations	Performed the experiments	Investigation	YES
4397066	25875470	MI	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397066	25875470	MI	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397066	25875470	MI	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397066	25875470	MPA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397066	25875470	MPA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397066	25875470	MPA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397066	25875470	MPA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397066	25875470	OEO	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4397066	25875470	WBM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397066	25875470	WBM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397066	25875470	WBM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397066	25875470	WBM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6321346	30551629	E.B.	CRediT	writing--review & editing	writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6321346	30551629	G.J.	CRediT	Conceptualization|data curation|writing--original draft	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6321346	30551629	G.J.	CRediT	Conceptualization|data curation|writing--original draft	data curation	Analyzed the data	Data curation	YES
6321346	30551629	G.J.	CRediT	Conceptualization|data curation|writing--original draft	writing--original draft	Wrote the paper	Writing - Original Draft	YES
6321346	30551629	I.A.	CRediT	Conceptualization|resources|supervision|writing--review & editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6321346	30551629	I.A.	CRediT	Conceptualization|resources|supervision|writing--review & editing	resources	Contributed reagents/materials/analysis tools	Resources	YES
6321346	30551629	I.A.	CRediT	Conceptualization|resources|supervision|writing--review & editing	supervision	-	Supervision	YES
6321346	30551629	I.A.	CRediT	Conceptualization|resources|supervision|writing--review & editing	writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6321346	30551629	M.K.	CRediT	formal analysis|methodology	formal analysis	Analyzed the data	Formal analysis	YES
6321346	30551629	M.K.	CRediT	formal analysis|methodology	methodology	Performed the experiments	Methodology	YES
6321346	30551629	T.B.	CRediT	visualization	visualization	Analyzed the data	Visualization	YES
6321346	30551629	V.F.	CRediT	methodology|project administration	methodology	Performed the experiments	Methodology	YES
6321346	30551629	V.F.	CRediT	methodology|project administration	project administration	-	Project administration	YES
6377924	30936793	Each author	2	had role in drafting the work and revising it critically for important intellectual content|gave final approval of the version to be published and they are agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	had role in drafting the work and revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6377924	30936793	Each author	2	had role in drafting the work and revising it critically for important intellectual content|gave final approval of the version to be published and they are agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	gave final approval of the version to be published and they are agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	-	-	NO
6377924	30936793	S.S.	2	gave substantial contribution to the conception or design of the work and in the acquisition, analysis and interpretation of data for the work|gave substantial contribution to the conception or design of the work and in the acquisition, analysis and interpretation of data for the work	gave substantial contribution to the conception or design of the work and in the acquisition, analysis and interpretation of data for the work	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
6377924	30936793	S.S.	2	gave substantial contribution to the conception or design of the work and in the acquisition, analysis and interpretation of data for the work|gave substantial contribution to the conception or design of the work and in the acquisition, analysis and interpretation of data for the work	gave substantial contribution to the conception or design of the work and in the acquisition, analysis and interpretation of data for the work	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
5423905	28539927	C-TY	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5423905	28539927	JS	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5423905	28539927	NS	PLoS52	designed the work	designed the work	Conceived and designed the experiments	-	YES
5423905	28539927	PS	PLoS52	designed the work	designed the work	Conceived and designed the experiments	-	YES
5423905	28539927	SL	PLoS52	designed the work|analyzed the data	designed the work	Conceived and designed the experiments	-	YES
5423905	28539927	SL	PLoS52	designed the work|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5423905	28539927	WB	PLoS52	designed the work|analyzed the data	designed the work	Conceived and designed the experiments	-	YES
5423905	28539927	WB	PLoS52	designed the work|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5423905	28539927	WM	PLoS52	designed the work|analyzed the data	designed the work	Conceived and designed the experiments	-	YES
5423905	28539927	WM	PLoS52	designed the work|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
3162878	21762513	AK	2	carried out the kinetic studies and participated in the design of the study	carried out the kinetic studies and participated in the design of the study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3162878	21762513	AOG	2	carried ot the synthesis of the starting metarials	carried ot the synthesis of the starting metarials	Performed the experiments	Investigation	YES
3162878	21762513	HKA	2	carried out the kinetic studies and participated in the design of the study	carried out the kinetic studies and participated in the design of the study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3162878	21762513	MA	2	carried ot the synthesis of the starting metarials	carried ot the synthesis of the starting metarials	Performed the experiments	Investigation	YES
3162878	21762513	MK	2	has coordinated the study and characterization of the compound 1	has coordinated the study and characterization of the compound 1	Performed the experiments	Investigation|Project administration	YES
3162878	21762513	NA	2	carried out the synthesis of the compound 1	carried out the synthesis of the compound 1	Performed the experiments	Investigation	YES
4990864	27538502	CW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4990864	27538502	CW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4990864	27538502	CW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4990864	27538502	CW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4990864	27538502	JG	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4990864	27538502	JG	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4990864	27538502	JG	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4990864	27538502	RJ	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4990864	27538502	RJ	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4990864	27538502	SA	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4990864	27538502	SA	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4990864	27538502	SS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4397068	25875095	AT	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4397068	25875095	HK	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4397068	25875095	HM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397068	25875095	HM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4397068	25875095	HM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397068	25875095	HO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397068	25875095	HO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397068	25875095	HO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397068	25875095	HO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397068	25875095	HO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397068	25875095	HT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397068	25875095	HT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397068	25875095	HT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397068	25875095	HT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397068	25875095	HT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397068	25875095	MI	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397068	25875095	MI	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4397068	25875095	MI	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397068	25875095	MO	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397068	25875095	MO	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4397068	25875095	MO	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397068	25875095	MW	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4397068	25875095	NG	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397068	25875095	NG	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4397068	25875095	NG	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397068	25875095	NN	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4397068	25875095	TT	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4397068	25875095	YK	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397068	25875095	YK	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4397068	25875095	YK	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397068	25875095	YM	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
3169447	21846387	HSS	2	designed the study, analyzed the data and drafted the manuscript	designed the study, analyzed the data and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3169447	21846387	MAM	2	prepared the organic ligand and its complexes	prepared the organic ligand and its complexes	-	-	NO
6377925	30936791	E.S.	2	gave substantial contribution to the conception or design of the work and in the acquisition, analysis and interpretation of data for the work	gave substantial contribution to the conception or design of the work and in the acquisition, analysis and interpretation of data for the work	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
6377925	30936791	Each author	2	gave final approval of the version to be published and they are agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	gave final approval of the version to be published and they are agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	-	-	NO
6377925	30936791	J.C.	2	had role in drafting the work and revising it critically for important intellectual content	had role in drafting the work and revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6377925	30936791	R.G.	2	had role in drafting the work and revising it critically for important intellectual content	had role in drafting the work and revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6377925	30936791	T.C.	2	gave substantial contribution to the conception or design of the work and in the acquisition, analysis and interpretation of data for the work|had role in drafting the work and revising it critically for important intellectual content	gave substantial contribution to the conception or design of the work and in the acquisition, analysis and interpretation of data for the work	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
6377925	30936791	T.C.	2	gave substantial contribution to the conception or design of the work and in the acquisition, analysis and interpretation of data for the work|had role in drafting the work and revising it critically for important intellectual content	had role in drafting the work and revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6023493	29794992	All authors	2	reviewed the manuscript and approved the final version	reviewed the manuscript and approved the final version	Wrote the paper	Writing - Review & Editing	YES
6023493	29794992	K.S.	2	contributed to data interpretation and wrote the first draft of the manuscript	contributed to data interpretation and wrote the first draft of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6023493	29794992	Y.S.	2	conceptualized the study	conceptualized the study	Conceived and designed the experiments	Conceptualization	YES
6321354	30388756	A.A.	2	worked on conceptualization, analyzed the data, and outlined the manuscript|contributed to the writing-review and editing of the full version	worked on conceptualization, analyzed the data, and outlined the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
6321354	30388756	A.A.	2	worked on conceptualization, analyzed the data, and outlined the manuscript|contributed to the writing-review and editing of the full version	contributed to the writing-review and editing of the full version	Wrote the paper	Writing - Review & Editing	YES
6321354	30388756	A.D.	2	worked on conceptualization, analyzed the data, and outlined the manuscript	worked on conceptualization, analyzed the data, and outlined the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
6321354	30388756	E.M.Z.	2	worked on conceptualization, analyzed the data, and outlined the manuscript|contributed to the writing-review and editing of the full version	worked on conceptualization, analyzed the data, and outlined the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
6321354	30388756	E.M.Z.	2	worked on conceptualization, analyzed the data, and outlined the manuscript|contributed to the writing-review and editing of the full version	contributed to the writing-review and editing of the full version	Wrote the paper	Writing - Review & Editing	YES
6321354	30388756	M.M.	2	worked on conceptualization, analyzed the data, and outlined the manuscript	worked on conceptualization, analyzed the data, and outlined the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
6321354	30388756	S.B.-S.	2	worked on conceptualization, analyzed the data, and outlined the manuscript|contributed to the writing-review and editing of the full version	worked on conceptualization, analyzed the data, and outlined the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
6321354	30388756	S.B.-S.	2	worked on conceptualization, analyzed the data, and outlined the manuscript|contributed to the writing-review and editing of the full version	contributed to the writing-review and editing of the full version	Wrote the paper	Writing - Review & Editing	YES
6321354	30388756	S.K.	2	worked on conceptualization, analyzed the data, and outlined the manuscript|contributed to the writing-review and editing of the full version	worked on conceptualization, analyzed the data, and outlined the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
6321354	30388756	S.K.	2	worked on conceptualization, analyzed the data, and outlined the manuscript|contributed to the writing-review and editing of the full version	contributed to the writing-review and editing of the full version	Wrote the paper	Writing - Review & Editing	YES
5423917	28539930	All authors	2	agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	-	-	NO
5423917	28539930	ET	2	is responsible for article writing, model creation and adaptation, computational code creation, results, analysis, article editing and revision	is responsible for article writing, model creation and adaptation, computational code creation, results, analysis, article editing and revision	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5423917	28539930	SP	2	is responsible for computational code editing, article editing and revision	is responsible for computational code editing, article editing and revision	Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5423917	28539930	TF	2	is responsible for model creation and adaptation, results, analysis, article editing and revision	is responsible for model creation and adaptation, results, analysis, article editing and revision	Performed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5423917	28539930	WF	2	is responsible for motivating the project, the biological and agrochemical consultation, article editing and revision	is responsible for motivating the project, the biological and agrochemical consultation, article editing and revision	Wrote the paper	Writing - Review & Editing	YES
4397070	25875935	AL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397070	25875935	AL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397070	25875935	AL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397070	25875935	AL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397070	25875935	AL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397070	25875935	CA	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4397070	25875935	CA	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397070	25875935	CP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4397070	25875935	CS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4397070	25875935	CS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4397070	25875935	EGG	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4397070	25875935	EGG	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4397070	25875935	EGG	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397070	25875935	EP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4397070	25875935	FP	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4397070	25875935	FP	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4397070	25875935	LC	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4397070	25875935	LC	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4397070	25875935	LS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397070	25875935	LS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397070	25875935	LS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397070	25875935	LS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397070	25875935	MG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397070	25875935	MG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397070	25875935	MG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397070	25875935	MG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397070	25875935	PA	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4397070	25875935	PA	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4397070	25875935	RS	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397070	25875935	RS	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397070	25875935	RV	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4397070	25875935	SR	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4397070	25875935	TS	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397070	25875935	TS	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397070	25875935	VG	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4397070	25875935	VG	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4397070	25875935	VG	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
6377926	30936784	All the authors	2	were involved during data collection, analysis, documentation of the collection and writing the publication	were involved during data collection, analysis, documentation of the collection and writing the publication	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Formal analysis|Investigation	YES
4990865	27538518	All authors	2	discussed the results and commented on the manuscript	discussed the results and commented on the manuscript	-	-	NO
4990865	27538518	BY	2	designed the experiments and wrote the manuscript	designed the experiments and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4990865	27538518	DTL	2	helped to perform the experiments	helped to perform the experiments	Performed the experiments	Investigation	YES
4990865	27538518	JBL	2	helped to perform the experiments	helped to perform the experiments	Performed the experiments	Investigation	YES
4990865	27538518	ZCX	2	conceived the experiments	conceived the experiments	Conceived and designed the experiments	Conceptualization	YES
4990865	27538518	ZWX	2	helped to perform the experiments	helped to perform the experiments	Performed the experiments	Investigation	YES
3178480	21861904	HT	2	helped to draft the manuscript	helped to draft the manuscript	Wrote the paper	Writing - Original Draft	YES
3178480	21861904	YF	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
6321357	30453503	C.W.	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
6321357	30453503	G.Z.	CRediT	Data curation	Data curation	Analyzed the data	Data curation	YES
6321357	30453503	J.Z.	CRediT	Writing--original draft	Writing--original draft	Wrote the paper	Writing - Original Draft	YES
6321357	30453503	T.T.	CRediT	Software	Software	Contributed reagents/materials/analysis tools	Software	YES
6321357	30453503	W.D.	CRediT	Writing--original draft	Writing--original draft	Wrote the paper	Writing - Original Draft	YES
6321357	30453503	X.C.	CRediT	Data curation	Data curation	Analyzed the data	Data curation	YES
6321357	30453503	X.L.	CRediT	Conceptualization|Project administration|Resources	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6321357	30453503	X.L.	CRediT	Conceptualization|Project administration|Resources	Project administration	-	Project administration	YES
6321357	30453503	X.L.	CRediT	Conceptualization|Project administration|Resources	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6321357	30453503	Z.L.	CRediT	Supervision	Supervision	-	Supervision	YES
5423943	28539928	AH	2	provided valuable input for improving the manuscript	provided valuable input for improving the manuscript	Wrote the paper	Writing - Review & Editing	YES
5423943	28539928	AK	2	provided support in discussion of the results	provided support in discussion of the results	-	-	NO
5423943	28539928	CN	2	provided valuable input for improving the manuscript	provided valuable input for improving the manuscript	Wrote the paper	Writing - Review & Editing	YES
5423943	28539928	IL	2	added valuable contribution to each chapter and in manifold discussions	added valuable contribution to each chapter and in manifold discussions	-	-	NO
5423943	28539928	JC-B	2	provided valuable input for improving the manuscript	provided valuable input for improving the manuscript	Wrote the paper	Writing - Review & Editing	YES
5423943	28539928	MW	2	provided valuable input for improving the manuscript	provided valuable input for improving the manuscript	Wrote the paper	Writing - Review & Editing	YES
5423943	28539928	OK	2	provided valuable input for improving the manuscript	provided valuable input for improving the manuscript	Wrote the paper	Writing - Review & Editing	YES
5423943	28539928	YI	2	was leading the writing process	was leading the writing process	Wrote the paper	-	YES
6377927	30936789	A.Z.	2	conceived the idea, acquisition and coordination, contributed to design, drafting of the manuscript	conceived the idea, acquisition and coordination, contributed to design, drafting of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Project administration|Writing - Original Draft	YES
6377927	30936789	E.B.	2	contributed to acquisition of data	contributed to acquisition of data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
6377927	30936789	E.H.	2	data collection, managed database	data collection, managed database	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Investigation|Software	YES
6377927	30936789	E.N.	2	contributed to design, drafting of the final manuscript	contributed to design, drafting of the final manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6377927	30936789	J.H.	2	recruitment of patients, data collection and statistical analyses	recruitment of patients, data collection and statistical analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6377927	30936789	M.A.	2	contributed to conception and design	contributed to conception and design	Conceived and designed the experiments	Conceptualization	YES
6023499	29772649	All authors	2	were involved in the drafting of the manuscript|agreed with the final version of this manuscript	were involved in the drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
6023499	29772649	All authors	2	were involved in the drafting of the manuscript|agreed with the final version of this manuscript	agreed with the final version of this manuscript	-	-	NO
4397071	25875914	HM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397071	25875914	HM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397071	25875914	HM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397071	25875914	HM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397071	25875914	HM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397071	25875914	K. Sato	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4397071	25875914	K. Suda	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397071	25875914	K. Suda	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397071	25875914	K. Suda	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397071	25875914	K. Suda	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397071	25875914	KN	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397071	25875914	ST	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4397071	25875914	ST	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397071	25875914	TM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397071	25875914	TM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397071	25875914	TM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397071	25875914	YF	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4397071	25875914	YK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4397071	25875914	YM	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397071	25875914	YS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
3180263	21867559	CD	2	participated in the design, operation and data analysis of smoke transfer efficiency studies	participated in the design, operation and data analysis of smoke transfer efficiency studies	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
3180263	21867559	DA	2	performed fluorometric deposition assessments	performed fluorometric deposition assessments	Performed the experiments	Investigation	YES
3180263	21867559	GA	2	participated in the experimental design of the study and performed statistical analysis	participated in the experimental design of the study and performed statistical analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
3180263	21867559	JA	2	carried out cell culture, whole smoke exposure, cytotoxicity assays, syringe validation, smoke transfer efficiency studies and drafted the manuscript	carried out cell culture, whole smoke exposure, cytotoxicity assays, syringe validation, smoke transfer efficiency studies and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Validation|Writing - Original Draft	YES
3180263	21867559	JMcA	2	participated in the design, operation and data analysis of smoke transfer efficiency studies	participated in the design, operation and data analysis of smoke transfer efficiency studies	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
3180263	21867559	MG	2	conceived the study, participated in its design and coordination and drafted the manuscript	conceived the study, participated in its design and coordination and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
6377928	30936792	A.S-N	2	had role in drafting the work and revising it critically for important intellectual content	had role in drafting the work and revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6377928	30936792	D.P.	2	had role in drafting the work and revising it critically for important intellectual content	had role in drafting the work and revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6377928	30936792	Each author	2	gave final approval of the version to be published and they are agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	gave final approval of the version to be published and they are agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	-	-	NO
6377928	30936792	H.P-J	2	had role in drafting the work and revising it critically for important intellectual content	had role in drafting the work and revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6377928	30936792	J.P.	2	gave substantial contribution to the conception or design of the work and in the acquisition, analysis and interpretation of data for the work|had role in drafting the work and revising it critically for important intellectual content	gave substantial contribution to the conception or design of the work and in the acquisition, analysis and interpretation of data for the work	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
6377928	30936792	J.P.	2	gave substantial contribution to the conception or design of the work and in the acquisition, analysis and interpretation of data for the work|had role in drafting the work and revising it critically for important intellectual content	had role in drafting the work and revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6377928	30936792	M.H.	2	also gave the contribution in the acquisition of the data	also gave the contribution in the acquisition of the data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
6377928	30936792	N.S.	2	gave substantial contribution to the conception or design of the work and in the acquisition, analysis and interpretation of data for the work|had role in drafting the work and revising it critically for important intellectual content	gave substantial contribution to the conception or design of the work and in the acquisition, analysis and interpretation of data for the work	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
6377928	30936792	N.S.	2	gave substantial contribution to the conception or design of the work and in the acquisition, analysis and interpretation of data for the work|had role in drafting the work and revising it critically for important intellectual content	had role in drafting the work and revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6377928	30936792	R.J.	2	also gave the contribution in the acquisition of the data	also gave the contribution in the acquisition of the data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
6377928	30936792	S.A.	2	also gave the contribution in the acquisition of the data|had role in drafting the work and revising it critically for important intellectual content	also gave the contribution in the acquisition of the data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
6377928	30936792	S.A.	2	also gave the contribution in the acquisition of the data|had role in drafting the work and revising it critically for important intellectual content	had role in drafting the work and revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6321358	30275390	J.Z.	CRediT	Conceptualization|Methodology|Methodology|Software|Validation|Formal analysis|Data curation|Writing-original draft preparation|Supervision|Project administration|Funding acquisition	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6321358	30275390	J.Z.	CRediT	Conceptualization|Methodology|Methodology|Software|Validation|Formal analysis|Data curation|Writing-original draft preparation|Supervision|Project administration|Funding acquisition	Methodology	Performed the experiments	Methodology	YES
6321358	30275390	J.Z.	CRediT	Conceptualization|Methodology|Methodology|Software|Validation|Formal analysis|Data curation|Writing-original draft preparation|Supervision|Project administration|Funding acquisition	Methodology	Performed the experiments	Methodology	YES
6321358	30275390	J.Z.	CRediT	Conceptualization|Methodology|Methodology|Software|Validation|Formal analysis|Data curation|Writing-original draft preparation|Supervision|Project administration|Funding acquisition	Software	Contributed reagents/materials/analysis tools	Software	YES
6321358	30275390	J.Z.	CRediT	Conceptualization|Methodology|Methodology|Software|Validation|Formal analysis|Data curation|Writing-original draft preparation|Supervision|Project administration|Funding acquisition	Validation	Performed the experiments	Validation	YES
6321358	30275390	J.Z.	CRediT	Conceptualization|Methodology|Methodology|Software|Validation|Formal analysis|Data curation|Writing-original draft preparation|Supervision|Project administration|Funding acquisition	Formal analysis	Analyzed the data	Formal analysis	YES
6321358	30275390	J.Z.	CRediT	Conceptualization|Methodology|Methodology|Software|Validation|Formal analysis|Data curation|Writing-original draft preparation|Supervision|Project administration|Funding acquisition	Data curation	Analyzed the data	Data curation	YES
6321358	30275390	J.Z.	CRediT	Conceptualization|Methodology|Methodology|Software|Validation|Formal analysis|Data curation|Writing-original draft preparation|Supervision|Project administration|Funding acquisition	Writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
6321358	30275390	J.Z.	CRediT	Conceptualization|Methodology|Methodology|Software|Validation|Formal analysis|Data curation|Writing-original draft preparation|Supervision|Project administration|Funding acquisition	Supervision	-	Supervision	YES
6321358	30275390	J.Z.	CRediT	Conceptualization|Methodology|Methodology|Software|Validation|Formal analysis|Data curation|Writing-original draft preparation|Supervision|Project administration|Funding acquisition	Project administration	-	Project administration	YES
6321358	30275390	J.Z.	CRediT	Conceptualization|Methodology|Methodology|Software|Validation|Formal analysis|Data curation|Writing-original draft preparation|Supervision|Project administration|Funding acquisition	Funding acquisition	-	Funding acquisition	YES
6321358	30275390	S.W.	CRediT	Methodology|Software|Formal analysis|Resources	Methodology	Performed the experiments	Methodology	YES
6321358	30275390	S.W.	CRediT	Methodology|Software|Formal analysis|Resources	Software	Contributed reagents/materials/analysis tools	Software	YES
6321358	30275390	S.W.	CRediT	Methodology|Software|Formal analysis|Resources	Formal analysis	Analyzed the data	Formal analysis	YES
6321358	30275390	S.W.	CRediT	Methodology|Software|Formal analysis|Resources	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6321358	30275390	T.Y.	CRediT	Conceptualization|Writing-review & editing|Supervision|Project administration|Funding acquisition	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6321358	30275390	T.Y.	CRediT	Conceptualization|Writing-review & editing|Supervision|Project administration|Funding acquisition	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6321358	30275390	T.Y.	CRediT	Conceptualization|Writing-review & editing|Supervision|Project administration|Funding acquisition	Supervision	-	Supervision	YES
6321358	30275390	T.Y.	CRediT	Conceptualization|Writing-review & editing|Supervision|Project administration|Funding acquisition	Project administration	-	Project administration	YES
6321358	30275390	T.Y.	CRediT	Conceptualization|Writing-review & editing|Supervision|Project administration|Funding acquisition	Funding acquisition	-	Funding acquisition	YES
4991007	27538394	BL	2	revised the manuscript for several times	revised the manuscript for several times	Wrote the paper	Writing - Review & Editing	YES
4991007	27538394	JD	2	provided the plant samples for sequencing	provided the plant samples for sequencing	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4991007	27538394	LD	2	revised the manuscript for several times	revised the manuscript for several times	Wrote the paper	Writing - Review & Editing	YES
4991007	27538394	YJ	2	performed the rna seq data analysis|wrote the manuscript	performed the rna seq data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4991007	27538394	YJ	2	performed the rna seq data analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4991007	27538394	YS	2	revised the manuscript for several times	revised the manuscript for several times	Wrote the paper	Writing - Review & Editing	YES
4991007	27538394	YZ	2	provided the plant samples for sequencing|did the validation experiments in the study|wrote the manuscript	provided the plant samples for sequencing	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4991007	27538394	YZ	2	provided the plant samples for sequencing|did the validation experiments in the study|wrote the manuscript	did the validation experiments in the study	Performed the experiments	Investigation|Validation	YES
4991007	27538394	YZ	2	provided the plant samples for sequencing|did the validation experiments in the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4991007	27538394	ZL	2	designed and supervised all aspects of the study|revised the manuscript for several times	designed and supervised all aspects of the study	Conceived and designed the experiments	Methodology|Supervision	YES
4991007	27538394	ZL	2	designed and supervised all aspects of the study|revised the manuscript for several times	revised the manuscript for several times	Wrote the paper	Writing - Review & Editing	YES
4397072	25875297	BG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397072	25875297	BG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397072	25875297	BG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397072	25875297	BG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397072	25875297	CS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397072	25875297	CS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397072	25875297	CS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397072	25875297	CS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397072	25875297	DM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397072	25875297	DM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397072	25875297	DM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397072	25875297	DM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397072	25875297	GGA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397072	25875297	GGA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397072	25875297	GGA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397072	25875297	GGA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397072	25875297	HR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397072	25875297	HR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397072	25875297	HR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397072	25875297	HR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397072	25875297	JR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397072	25875297	JR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397072	25875297	JR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397072	25875297	JR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397072	25875297	MCO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397072	25875297	MCO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397072	25875297	MCO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397072	25875297	MCO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397072	25875297	MYS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397072	25875297	MYS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397072	25875297	MYS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397072	25875297	MYS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397072	25875297	MYS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397072	25875297	RCH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397072	25875297	RCH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397072	25875297	RCH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397072	25875297	RCH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397072	25875297	RMH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397072	25875297	RMH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397072	25875297	RMH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397072	25875297	RMH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397072	25875297	SC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397072	25875297	SC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397072	25875297	SC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397072	25875297	SC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397072	25875297	SC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397072	25875297	VSP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397072	25875297	VSP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397072	25875297	VSP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397072	25875297	VSP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5423983	28539933	AD	2	designed the study|performed the transmission experiment and sampled the material	designed the study	Conceived and designed the experiments	Methodology	YES
5423983	28539933	AD	2	designed the study|performed the transmission experiment and sampled the material	performed the transmission experiment and sampled the material	Performed the experiments	Investigation	YES
5423983	28539933	DZ	2	analyzed and interpreted data|contributed with bioinformatics assistance	analyzed and interpreted data	Analyzed the data	Formal analysis	YES
5423983	28539933	DZ	2	analyzed and interpreted data|contributed with bioinformatics assistance	contributed with bioinformatics assistance	-	Formal analysis	YES
5423983	28539933	EA	2	performed the transmission experiment and sampled the material	performed the transmission experiment and sampled the material	Performed the experiments	Investigation	YES
5423983	28539933	GL	2	performed the transmission experiment and sampled the material	performed the transmission experiment and sampled the material	Performed the experiments	Investigation	YES
5423983	28539933	GT	2	performed the transmission experiment and sampled the material	performed the transmission experiment and sampled the material	Performed the experiments	Investigation	YES
5423983	28539933	HB	2	prepared the d	prepared the d	-	-	NO
5423983	28539933	LdH	2	designed the study|conducted all bioinformatics analysis and performed sample processing and qpcr experiments|analyzed and interpreted data|performed the transmission experiment and sampled the material|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5423983	28539933	LdH	2	designed the study|conducted all bioinformatics analysis and performed sample processing and qpcr experiments|analyzed and interpreted data|performed the transmission experiment and sampled the material|wrote the manuscript	conducted all bioinformatics analysis and performed sample processing and qpcr experiments	Performed the experiments	Data curation|Formal analysis|Investigation	YES
5423983	28539933	LdH	2	designed the study|conducted all bioinformatics analysis and performed sample processing and qpcr experiments|analyzed and interpreted data|performed the transmission experiment and sampled the material|wrote the manuscript	analyzed and interpreted data	Analyzed the data	Formal analysis	YES
5423983	28539933	LdH	2	designed the study|conducted all bioinformatics analysis and performed sample processing and qpcr experiments|analyzed and interpreted data|performed the transmission experiment and sampled the material|wrote the manuscript	performed the transmission experiment and sampled the material	Performed the experiments	Investigation	YES
5423983	28539933	LdH	2	designed the study|conducted all bioinformatics analysis and performed sample processing and qpcr experiments|analyzed and interpreted data|performed the transmission experiment and sampled the material|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5423983	28539933	M-CS	2	designed the study|analyzed and interpreted data	designed the study	Conceived and designed the experiments	Methodology	YES
5423983	28539933	M-CS	2	designed the study|analyzed and interpreted data	analyzed and interpreted data	Analyzed the data	Formal analysis	YES
5423983	28539933	MM	2	designed the study|performed the transmission experiment and sampled the material	designed the study	Conceived and designed the experiments	Methodology	YES
5423983	28539933	MM	2	designed the study|performed the transmission experiment and sampled the material	performed the transmission experiment and sampled the material	Performed the experiments	Investigation	YES
5423983	28539933	MdV	2	designed the study|analyzed and interpreted data|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5423983	28539933	MdV	2	designed the study|analyzed and interpreted data|wrote the manuscript	analyzed and interpreted data	Analyzed the data	Formal analysis	YES
5423983	28539933	MdV	2	designed the study|analyzed and interpreted data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5423983	28539933	SA	2	designed the study|analyzed and interpreted data	designed the study	Conceived and designed the experiments	Methodology	YES
5423983	28539933	SA	2	designed the study|analyzed and interpreted data	analyzed and interpreted data	Analyzed the data	Formal analysis	YES
5423983	28539933	VM	2	designed the study|analyzed and interpreted data	designed the study	Conceived and designed the experiments	Methodology	YES
5423983	28539933	VM	2	designed the study|analyzed and interpreted data	analyzed and interpreted data	Analyzed the data	Formal analysis	YES
6377929	30936796	M.J.	2	gave substantial contribution to the conception or design of the work and in the acquisition, analysis and interpretation of data for the work|had role in drafting the work and revising it critically for important intellectual content|gave final approval of the version to be published and agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	gave substantial contribution to the conception or design of the work and in the acquisition, analysis and interpretation of data for the work	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
6377929	30936796	M.J.	2	gave substantial contribution to the conception or design of the work and in the acquisition, analysis and interpretation of data for the work|had role in drafting the work and revising it critically for important intellectual content|gave final approval of the version to be published and agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	had role in drafting the work and revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6377929	30936796	M.J.	2	gave substantial contribution to the conception or design of the work and in the acquisition, analysis and interpretation of data for the work|had role in drafting the work and revising it critically for important intellectual content|gave final approval of the version to be published and agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	gave final approval of the version to be published and agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	-	-	NO
6321360	30562981	A.A.	CRediT	Visualization	Visualization	Analyzed the data	Visualization	YES
6321360	30562981	A.M.	CRediT	Project administration|Supervision	Project administration	-	Project administration	YES
6321360	30562981	A.M.	CRediT	Project administration|Supervision	Supervision	-	Supervision	YES
6321360	30562981	A.S.	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
6321360	30562981	E.P.	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
6321360	30562981	M.A.	CRediT	Funding acquisition|Project administration|Writing--original draft	Funding acquisition	-	Funding acquisition	YES
6321360	30562981	M.A.	CRediT	Funding acquisition|Project administration|Writing--original draft	Project administration	-	Project administration	YES
6321360	30562981	M.A.	CRediT	Funding acquisition|Project administration|Writing--original draft	Writing--original draft	Wrote the paper	Writing - Original Draft	YES
6321360	30562981	M.G.	CRediT	Funding acquisition|Supervision|Writing--original draft	Funding acquisition	-	Funding acquisition	YES
6321360	30562981	M.G.	CRediT	Funding acquisition|Supervision|Writing--original draft	Supervision	-	Supervision	YES
6321360	30562981	M.G.	CRediT	Funding acquisition|Supervision|Writing--original draft	Writing--original draft	Wrote the paper	Writing - Original Draft	YES
6321360	30562981	P.O.	CRediT	Investigation|Writing--original draft	Investigation	Performed the experiments	Investigation	YES
6321360	30562981	P.O.	CRediT	Investigation|Writing--original draft	Writing--original draft	Wrote the paper	Writing - Original Draft	YES
6321360	30562981	R.Y.	CRediT	Project administration|Supervision	Project administration	-	Project administration	YES
6321360	30562981	R.Y.	CRediT	Project administration|Supervision	Supervision	-	Supervision	YES
6321360	30562981	S.V.	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
6321360	30562981	V.C.	CRediT	Funding acquisition|Project administration|Supervision	Funding acquisition	-	Funding acquisition	YES
6321360	30562981	V.C.	CRediT	Funding acquisition|Project administration|Supervision	Project administration	-	Project administration	YES
6321360	30562981	V.C.	CRediT	Funding acquisition|Project administration|Supervision	Supervision	-	Supervision	YES
6321360	30562981	V.N.	CRediT	Visualization	Visualization	Analyzed the data	Visualization	YES
3180689	21867548	All authors	2	discussed the results and commented on the manuscript	discussed the results and commented on the manuscript	-	-	NO
3180689	21867548	KH	2	wrote the manuscript|supervised the project	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3180689	21867548	KH	2	wrote the manuscript|supervised the project	supervised the project	-	Supervision	YES
4397074	25874937	CWX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397074	25874937	CWX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397074	25874937	CWX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397074	25874937	CWX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397074	25874937	CWX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397074	25874937	GLB	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397074	25874937	LJP	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397074	25874937	QAJ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397074	25874937	QW	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4397074	25874937	YL	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4991039	27538483	CT	PLoS52	conceived and designed the experiments|performed the data analyses|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4991039	27538483	CT	PLoS52	conceived and designed the experiments|performed the data analyses|wrote the paper	performed the data analyses	Analyzed the data	Formal analysis	YES
4991039	27538483	CT	PLoS52	conceived and designed the experiments|performed the data analyses|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4991039	27538483	FL	PLoS52	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
4991039	27538483	HL	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4991039	27538483	JS	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4991039	27538483	JW	PLoS52	carried out the experiments|performed the data analyses	carried out the experiments	Performed the experiments	Investigation	YES
4991039	27538483	JW	PLoS52	carried out the experiments|performed the data analyses	performed the data analyses	Analyzed the data	Formal analysis	YES
4991039	27538483	MM	PLoS52	carried out the experiments|performed the data analyses|wrote the paper	carried out the experiments	Performed the experiments	Investigation	YES
4991039	27538483	MM	PLoS52	carried out the experiments|performed the data analyses|wrote the paper	performed the data analyses	Analyzed the data	Formal analysis	YES
4991039	27538483	MM	PLoS52	carried out the experiments|performed the data analyses|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4991039	27538483	ST	PLoS52	carried out the experiments|performed the data analyses	carried out the experiments	Performed the experiments	Investigation	YES
4991039	27538483	ST	PLoS52	carried out the experiments|performed the data analyses	performed the data analyses	Analyzed the data	Formal analysis	YES
6023512	29695061	Alessandro Crisci	1	The main framework of the paper	The main framework of the paper	-	-	NO
6023512	29695061	Anna Licito	1	Manuscript correction	Manuscript correction	Wrote the paper	Writing - Review & Editing	YES
6023512	29695061	Edda Serra	1	The main framework of the paper	The main framework of the paper	-	-	NO
6023512	29695061	Giulio Benincasa	1	Preparation of the manuscript	Preparation of the manuscript	Wrote the paper	Writing - Original Draft	YES
6023512	29695061	Giuseppe Marotta	1	Manuscript correction	Manuscript correction	Wrote the paper	Writing - Review & Editing	YES
6023512	29695061	Michela Crisci	1	Preparation of the manuscript	Preparation of the manuscript	Wrote the paper	Writing - Original Draft	YES
6377930	30936797	Each author	2	gave final approval of the version to be published and they are agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	gave final approval of the version to be published and they are agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	-	-	NO
6377930	30936797	N.S.	2	gave substantial contribution to the conception or design of the work and in the acquisition, analysis and interpretation of data for the work	gave substantial contribution to the conception or design of the work and in the acquisition, analysis and interpretation of data for the work	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
6377930	30936797	R.J.	2	had role in drafting the work and revising it critically for important intellectual content	had role in drafting the work and revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6377930	30936797	T.C.	2	had role in drafting the work and revising it critically for important intellectual content	had role in drafting the work and revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6377930	30936797	V.G.	2	gave substantial contribution to the conception or design of the work and in the acquisition, analysis and interpretation of data for the work|had role in drafting the work and revising it critically for important intellectual content	gave substantial contribution to the conception or design of the work and in the acquisition, analysis and interpretation of data for the work	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
6377930	30936797	V.G.	2	gave substantial contribution to the conception or design of the work and in the acquisition, analysis and interpretation of data for the work|had role in drafting the work and revising it critically for important intellectual content	had role in drafting the work and revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6321364	30513750	E.-J.C.	2	carried out experimental work and wrote the manuscript	carried out experimental work and wrote the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6321364	30513750	G.-W.C.	2	carried out experimental work and wrote the manuscript	carried out experimental work and wrote the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6321364	30513750	H.-Y.C.	2	designed and supervised this research|contributed to the final preparation of this paper and submission	designed and supervised this research	Conceived and designed the experiments	Methodology|Supervision	YES
6321364	30513750	H.-Y.C.	2	designed and supervised this research|contributed to the final preparation of this paper and submission	contributed to the final preparation of this paper and submission	-	-	NO
6321364	30513750	S.-J.Y.	2	performed the clinical trials	performed the clinical trials	Performed the experiments	Investigation	YES
6321364	30513750	Y.-B.L.	2	designed and supervised this research	designed and supervised this research	Conceived and designed the experiments	Methodology|Supervision	YES
5424304	28539929	ED	2	conducted the simulations and analysed the data|structured and wrote the manuscript|edited the manuscript	conducted the simulations and analysed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5424304	28539929	ED	2	conducted the simulations and analysed the data|structured and wrote the manuscript|edited the manuscript	structured and wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5424304	28539929	ED	2	conducted the simulations and analysed the data|structured and wrote the manuscript|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5424304	28539929	EM	2	conducted the simulations and analysed the data|structured and wrote the manuscript|edited the manuscript	conducted the simulations and analysed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5424304	28539929	EM	2	conducted the simulations and analysed the data|structured and wrote the manuscript|edited the manuscript	structured and wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5424304	28539929	EM	2	conducted the simulations and analysed the data|structured and wrote the manuscript|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5424304	28539929	JB	2	conducted the simulations and analysed the data|structured and wrote the manuscript|edited the manuscript	conducted the simulations and analysed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5424304	28539929	JB	2	conducted the simulations and analysed the data|structured and wrote the manuscript|edited the manuscript	structured and wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5424304	28539929	JB	2	conducted the simulations and analysed the data|structured and wrote the manuscript|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5424304	28539929	JL	2	conceived and designed the study|edited the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5424304	28539929	JL	2	conceived and designed the study|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5424304	28539929	JP	2	conceived and designed the study|conducted the simulations and analysed the data|structured and wrote the manuscript|edited the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5424304	28539929	JP	2	conceived and designed the study|conducted the simulations and analysed the data|structured and wrote the manuscript|edited the manuscript	conducted the simulations and analysed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5424304	28539929	JP	2	conceived and designed the study|conducted the simulations and analysed the data|structured and wrote the manuscript|edited the manuscript	structured and wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5424304	28539929	JP	2	conceived and designed the study|conducted the simulations and analysed the data|structured and wrote the manuscript|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5424304	28539929	MD	2	conducted the simulations and analysed the data|structured and wrote the manuscript|edited the manuscript	conducted the simulations and analysed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5424304	28539929	MD	2	conducted the simulations and analysed the data|structured and wrote the manuscript|edited the manuscript	structured and wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5424304	28539929	MD	2	conducted the simulations and analysed the data|structured and wrote the manuscript|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5424304	28539929	MP	2	conceived and designed the study|structured and wrote the manuscript|edited the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5424304	28539929	MP	2	conceived and designed the study|structured and wrote the manuscript|edited the manuscript	structured and wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5424304	28539929	MP	2	conceived and designed the study|structured and wrote the manuscript|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5424304	28539929	NH	2	conceived and designed the study|edited the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5424304	28539929	NH	2	conceived and designed the study|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5424304	28539929	PT	2	conceived and designed the study|structured and wrote the manuscript|edited the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5424304	28539929	PT	2	conceived and designed the study|structured and wrote the manuscript|edited the manuscript	structured and wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5424304	28539929	PT	2	conceived and designed the study|structured and wrote the manuscript|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5424304	28539929	VS	2	conceived and designed the study|edited the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5424304	28539929	VS	2	conceived and designed the study|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5424304	28539929	WP	2	conceived and designed the study|edited the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5424304	28539929	WP	2	conceived and designed the study|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
4397075	25875531	CCH	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397075	25875531	CCH	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397075	25875531	CCH	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397075	25875531	CKL	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397075	25875531	CKL	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397075	25875531	CYP	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397075	25875531	CYP	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397075	25875531	EC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4397075	25875531	EC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397075	25875531	TSHL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397075	25875531	TSHL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397075	25875531	TSHL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6023516	29783726	A.A.	CRediT	Conceptualization|Investigation|Writing-original draft preparation|Writing-review & editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6023516	29783726	A.A.	CRediT	Conceptualization|Investigation|Writing-original draft preparation|Writing-review & editing	Investigation	Performed the experiments	Investigation	YES
6023516	29783726	A.A.	CRediT	Conceptualization|Investigation|Writing-original draft preparation|Writing-review & editing	Writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
6023516	29783726	A.A.	CRediT	Conceptualization|Investigation|Writing-original draft preparation|Writing-review & editing	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6023516	29783726	A.A.L.	CRediT	Conceptualization|Investigation|Writing-original draft preparation	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6023516	29783726	A.A.L.	CRediT	Conceptualization|Investigation|Writing-original draft preparation	Investigation	Performed the experiments	Investigation	YES
6023516	29783726	A.A.L.	CRediT	Conceptualization|Investigation|Writing-original draft preparation	Writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
6023516	29783726	D.K.	CRediT	Investigation|Writing-review & editing	Investigation	Performed the experiments	Investigation	YES
6023516	29783726	D.K.	CRediT	Investigation|Writing-review & editing	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6023516	29783726	G.C.	CRediT	Investigation|Writing-original draft preparation|Writing-review & editing	Investigation	Performed the experiments	Investigation	YES
6023516	29783726	G.C.	CRediT	Investigation|Writing-original draft preparation|Writing-review & editing	Writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
6023516	29783726	G.C.	CRediT	Investigation|Writing-original draft preparation|Writing-review & editing	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6023516	29783726	P.D.	CRediT	Conceptualization|Investigation|Writing-original draft preparation	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6023516	29783726	P.D.	CRediT	Conceptualization|Investigation|Writing-original draft preparation	Investigation	Performed the experiments	Investigation	YES
6023516	29783726	P.D.	CRediT	Conceptualization|Investigation|Writing-original draft preparation	Writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
6023516	29783726	X.X.	CRediT	Visualization	Visualization	Analyzed the data	Visualization	YES
6377931	30936795	Anis Cerovac	2	gave substantial contributions to the conception or design of the work in acquisition, analysis, or interpretation of data for the work	gave substantial contributions to the conception or design of the work in acquisition, analysis, or interpretation of data for the work	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
6377931	30936795	Each author	2	had a part in article preparing for drafting or revising it critically for important intellectual content|gave final approval of the version to be published and agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	had a part in article preparing for drafting or revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6377931	30936795	Each author	2	had a part in article preparing for drafting or revising it critically for important intellectual content|gave final approval of the version to be published and agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	gave final approval of the version to be published and agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	-	-	NO
6191392	30333954	FZ	2	contributed equally to this work	contributed equally to this work	-	-	NO
6191392	30333954	ZZ	2	contributed equally to this work	contributed equally to this work	-	-	NO
3184049	21906282	INP	2	carried out the nmr analyses and drafted the manuscript	carried out the nmr analyses and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3184049	21906282	IR	2	spectroscopic characterization, element analysis interpretation	spectroscopic characterization, element analysis interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3184049	21906282	JI	2	performed the synthetic procedures, purification	performed the synthetic procedures, purification	Performed the experiments	Investigation	YES
3184049	21906282	KO	2	performed the fab-ms measurements	performed the fab-ms measurements	Performed the experiments	Investigation	YES
3184049	21906282	MT	2	performed the fab-ms measurements	performed the fab-ms measurements	Performed the experiments	Investigation	YES
3184049	21906282	SS	2	carried out the nmr analyses and drafted the manuscript	carried out the nmr analyses and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4991082	27538446	All authors	2	contributed to the analysis of data and writing of the manuscript and approved the final manuscript	contributed to the analysis of data and writing of the manuscript and approved the final manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft|Writing - Review & Editing	YES
4991082	27538446	B.Y.	2	performed all network-based analyses of the data	performed all network-based analyses of the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4991082	27538446	C.D.C.A.	2	collected and prepared the biological material|generated and processed the microarray data|generated and processed the qrt-pcr data	collected and prepared the biological material	Performed the experiments	Investigation	YES
4991082	27538446	C.D.C.A.	2	collected and prepared the biological material|generated and processed the microarray data|generated and processed the qrt-pcr data	generated and processed the microarray data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
4991082	27538446	C.D.C.A.	2	collected and prepared the biological material|generated and processed the microarray data|generated and processed the qrt-pcr data	generated and processed the qrt-pcr data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
4991082	27538446	E.Z.	2	generated and processed the microarray data	generated and processed the microarray data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
4991082	27538446	G.E.D.	2	collected and prepared the biological material|generated and processed the qrt-pcr data|conceived and designed the study	collected and prepared the biological material	Performed the experiments	Investigation	YES
4991082	27538446	G.E.D.	2	collected and prepared the biological material|generated and processed the qrt-pcr data|conceived and designed the study	generated and processed the qrt-pcr data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
4991082	27538446	G.E.D.	2	collected and prepared the biological material|generated and processed the qrt-pcr data|conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4991082	27538446	G.F.G.	2	generated and processed the qrt-pcr data	generated and processed the qrt-pcr data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
4991082	27538446	M.E.P.	2	collected and prepared the biological material|conceived and designed the study	collected and prepared the biological material	Performed the experiments	Investigation	YES
4991082	27538446	M.E.P.	2	collected and prepared the biological material|conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4991082	27538446	M.T.S.	2	generated and processed the microarray data	generated and processed the microarray data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
4991082	27538446	S.S.C.R.	2	collected and prepared the biological material|generated and processed the qrt-pcr data	collected and prepared the biological material	Performed the experiments	Investigation	YES
4991082	27538446	S.S.C.R.	2	collected and prepared the biological material|generated and processed the qrt-pcr data	generated and processed the qrt-pcr data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
4991082	27538446	T.G.	2	performed all network-based analyses of the data	performed all network-based analyses of the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4991082	27538446	T.M.	2	designed and supervised all aspects of the network-based analyses|conceived and designed the study	designed and supervised all aspects of the network-based analyses	Conceived and designed the experiments|Analyzed the data	Formal analysis|Supervision	YES
4991082	27538446	T.M.	2	designed and supervised all aspects of the network-based analyses|conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3184625	21929780	AR	2	participated in the experimental design and coordination and helped to draft the manuscript	participated in the experimental design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Project administration|Writing - Original Draft	YES
3184625	21929780	CHW	2	participated in the experimental design and coordination and helped to draft the manuscript	participated in the experimental design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Project administration|Writing - Original Draft	YES
3184625	21929780	ME	2	carried out the calorimetric measurements and participated in the design of the experiments and helped to draft the manuscript	carried out the calorimetric measurements and participated in the design of the experiments and helped to draft the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
3184625	21929780	RP	2	participated in the experimental design and coordination and helped to draft the manuscript	participated in the experimental design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Project administration|Writing - Original Draft	YES
3184625	21929780	SK	2	drafted the manuscript, synthesized the samples, and performed the data analysis	drafted the manuscript, synthesized the samples, and performed the data analysis	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3184625	21929780	WH	2	carried out the calorimetric measurements and participated in the design of the experiments and helped to draft the manuscript	carried out the calorimetric measurements and participated in the design of the experiments and helped to draft the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
6321372	30340346	B.G.R.	CRediT	Conceptualization|Writing--original draft preparation|Writing--review and editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6321372	30340346	B.G.R.	CRediT	Conceptualization|Writing--original draft preparation|Writing--review and editing	Writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6321372	30340346	B.G.R.	CRediT	Conceptualization|Writing--original draft preparation|Writing--review and editing	Writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6321372	30340346	J.Y.	CRediT	Conceptualization|Writing--original draft preparation|Writing--review and editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6321372	30340346	J.Y.	CRediT	Conceptualization|Writing--original draft preparation|Writing--review and editing	Writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6321372	30340346	J.Y.	CRediT	Conceptualization|Writing--original draft preparation|Writing--review and editing	Writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6321372	30340346	P.T.R.	CRediT	Conceptualization|Writing--original draft preparation|Writing--review and editing|Funding acquisition	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6321372	30340346	P.T.R.	CRediT	Conceptualization|Writing--original draft preparation|Writing--review and editing|Funding acquisition	Writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6321372	30340346	P.T.R.	CRediT	Conceptualization|Writing--original draft preparation|Writing--review and editing|Funding acquisition	Writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6321372	30340346	P.T.R.	CRediT	Conceptualization|Writing--original draft preparation|Writing--review and editing|Funding acquisition	Funding acquisition	-	Funding acquisition	YES
6321372	30340346	T.P.D.	CRediT	Writing--original draft preparation|Writing--review and editing|Funding acquisition	Writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6321372	30340346	T.P.D.	CRediT	Writing--original draft preparation|Writing--review and editing|Funding acquisition	Writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6321372	30340346	T.P.D.	CRediT	Writing--original draft preparation|Writing--review and editing|Funding acquisition	Funding acquisition	-	Funding acquisition	YES
6377932	30936787	A.S.	2	gave substantial contribution to the conception or design of the work and in the acquisition, analysis and interpretation of data for the work	gave substantial contribution to the conception or design of the work and in the acquisition, analysis and interpretation of data for the work	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
6377932	30936787	B.P.	2	gave substantial contribution to the conception or design of the work and in the acquisition, analysis and interpretation of data for the work	gave substantial contribution to the conception or design of the work and in the acquisition, analysis and interpretation of data for the work	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
6377932	30936787	D.I.	2	had role in drafting the work and revising it critically for important intellectual content	had role in drafting the work and revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6377932	30936787	D.L.	2	gave substantial contribution to the conception or design of the work and in the acquisition, analysis and interpretation of data for the work	gave substantial contribution to the conception or design of the work and in the acquisition, analysis and interpretation of data for the work	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
6377932	30936787	Each author	2	gave final approval of the version to be published and they are agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	gave final approval of the version to be published and they are agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	-	-	NO
6377932	30936787	G.P.	2	had role in drafting the work and revising it critically for important intellectual content	had role in drafting the work and revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6377932	30936787	I.G.	2	had role in drafting the work and revising it critically for important intellectual content	had role in drafting the work and revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6377932	30936787	R.F.	2	gave substantial contribution to the conception or design of the work and in the acquisition, analysis and interpretation of data for the work	gave substantial contribution to the conception or design of the work and in the acquisition, analysis and interpretation of data for the work	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
6377932	30936787	V.J.	2	gave substantial contribution to the conception or design of the work and in the acquisition, analysis and interpretation of data for the work	gave substantial contribution to the conception or design of the work and in the acquisition, analysis and interpretation of data for the work	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
6377932	30936787	Z.K.	2	had role in drafting the work and revising it critically for important intellectual content	had role in drafting the work and revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4397076	25875160	AL	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397076	25875160	AL	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397076	25875160	AL	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397076	25875160	AL	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397076	25875160	FC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397076	25875160	FC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397076	25875160	FC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397076	25875160	JC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397076	25875160	JC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397076	25875160	JC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397076	25875160	JC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397076	25875160	JS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397076	25875160	JS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397076	25875160	JS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397076	25875160	JW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397076	25875160	JW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397076	25875160	JW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397076	25875160	MW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397076	25875160	MW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397076	25875160	MW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397076	25875160	MW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397076	25875160	RB	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397076	25875160	RB	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397076	25875160	RB	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397076	25875160	RB	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397076	25875160	TL	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397076	25875160	TL	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397076	25875160	TL	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397076	25875160	TL	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397076	25875160	VC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397076	25875160	VC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397076	25875160	VC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397076	25875160	VC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397076	25875160	VC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5425484	28553301	MW	2	wrote the article|provided the majority of the photographs	wrote the article	Wrote the paper	Writing - Original Draft	YES
5425484	28553301	MW	2	wrote the article|provided the majority of the photographs	provided the majority of the photographs	-	Visualization	YES
5425484	28553301	TC	2	wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
6212373	30402369	AK	2	designed the experiments|analyzed the data and drafted the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
6212373	30402369	AK	2	designed the experiments|analyzed the data and drafted the manuscript	analyzed the data and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6212373	30402369	All authors	2	approve the final version of the draft	approve the final version of the draft	Wrote the paper	Writing - Original Draft	YES
6212373	30402369	PG	2	supervised the work	supervised the work	-	Supervision	YES
6212373	30402369	SPS	2	designed the experiments|carried out all the qpcrs|analyzed the data and drafted the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
6212373	30402369	SPS	2	designed the experiments|carried out all the qpcrs|analyzed the data and drafted the manuscript	carried out all the qpcrs	Performed the experiments	Investigation	YES
6212373	30402369	SPS	2	designed the experiments|carried out all the qpcrs|analyzed the data and drafted the manuscript	analyzed the data and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4992203	27542359	AH	2	secured funding, oversaw the project, analyzed data and edited manuscript	secured funding, oversaw the project, analyzed data and edited manuscript	Analyzed the data|Wrote the paper	Formal analysis|Funding acquisition|Supervision|Writing - Review & Editing	YES
4992203	27542359	LA	2	conducted experiments and edited manuscript	conducted experiments and edited manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4992203	27542359	RA	2	analyzed data and edited manuscript	analyzed data and edited manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4992203	27542359	RG	2	conducted experiments, analyzed data and drafted manuscript	conducted experiments, analyzed data and drafted manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6023542	29751497	A.B.	2	conception, design of perspectives, wrote, read and approved the manuscript	conception, design of perspectives, wrote, read and approved the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
6023542	29751497	M.Z.	2	conception, design of perspectives, wrote, read and approved the manuscript	conception, design of perspectives, wrote, read and approved the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
6321376	30355980	C.P.	CRediT	Conceptualization|Validation|Investigation|Data curation|Writing-original draft preparation	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6321376	30355980	C.P.	CRediT	Conceptualization|Validation|Investigation|Data curation|Writing-original draft preparation	Validation	Performed the experiments	Validation	YES
6321376	30355980	C.P.	CRediT	Conceptualization|Validation|Investigation|Data curation|Writing-original draft preparation	Investigation	Performed the experiments	Investigation	YES
6321376	30355980	C.P.	CRediT	Conceptualization|Validation|Investigation|Data curation|Writing-original draft preparation	Data curation	Analyzed the data	Data curation	YES
6321376	30355980	C.P.	CRediT	Conceptualization|Validation|Investigation|Data curation|Writing-original draft preparation	Writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
6321376	30355980	P.S.	CRediT	Conceptualization|Writing-review & editing|Visualization|Supervision|Project administration|Funding acquisition	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6321376	30355980	P.S.	CRediT	Conceptualization|Writing-review & editing|Visualization|Supervision|Project administration|Funding acquisition	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6321376	30355980	P.S.	CRediT	Conceptualization|Writing-review & editing|Visualization|Supervision|Project administration|Funding acquisition	Visualization	Analyzed the data	Visualization	YES
6321376	30355980	P.S.	CRediT	Conceptualization|Writing-review & editing|Visualization|Supervision|Project administration|Funding acquisition	Supervision	-	Supervision	YES
6321376	30355980	P.S.	CRediT	Conceptualization|Writing-review & editing|Visualization|Supervision|Project administration|Funding acquisition	Project administration	-	Project administration	YES
6321376	30355980	P.S.	CRediT	Conceptualization|Writing-review & editing|Visualization|Supervision|Project administration|Funding acquisition	Funding acquisition	-	Funding acquisition	YES
6321376	30355980	S.N.	CRediT	Methodology|Validation	Methodology	Performed the experiments	Methodology	YES
6321376	30355980	S.N.	CRediT	Methodology|Validation	Validation	Performed the experiments	Validation	YES
6321376	30355980	S.P.	CRediT	Software|Formal analysis|Resources	Software	Contributed reagents/materials/analysis tools	Software	YES
6321376	30355980	S.P.	CRediT	Software|Formal analysis|Resources	Formal analysis	Analyzed the data	Formal analysis	YES
6321376	30355980	S.P.	CRediT	Software|Formal analysis|Resources	Resources	Contributed reagents/materials/analysis tools	Resources	YES
3189110	21933409	JR-M	5	synthesized the title compounds under the guidance of AR	synthesized the title compounds under the guidance of AR	Performed the experiments	Investigation|Supervision	YES
3189110	21933409	JS-B	5	synthesized the title compounds under the guidance of AR	synthesized the title compounds under the guidance of AR	Performed the experiments	Investigation|Supervision	YES
3189110	21933409	LP	5	collected the x-ray data and solved the crystal structures under the guidance of MD	collected the x-ray data and solved the crystal structures under the guidance of MD	Performed the experiments	Investigation|Supervision	YES
3201894	21982269	EB	2	prepared a first draft, which was discussed with all authors|further developed the article in the light of external peer reviews	prepared a first draft, which was discussed with all authors	Wrote the paper	Writing - Original Draft	YES
3201894	21982269	EB	2	prepared a first draft, which was discussed with all authors|further developed the article in the light of external peer reviews	further developed the article in the light of external peer reviews	Wrote the paper	Writing - Original Draft	YES
3201894	21982269	SP	2	further developed the article in the light of external peer reviews	further developed the article in the light of external peer reviews	Wrote the paper	Writing - Original Draft	YES
4397077	25876040	DH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397077	25876040	DH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397077	25876040	DH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397077	25876040	DH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397077	25876040	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397077	25876040	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397077	25876040	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397077	25876040	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397077	25876040	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397077	25876040	RS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397077	25876040	RS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397077	25876040	RS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397077	25876040	RS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6385058	30800609	Paredes Lopez Octavio	2	all contributed equally in this research	all contributed equally in this research	-	-	NO
6385058	30800609	Sharma Ashutosh	2	all contributed equally in this research	all contributed equally in this research	-	-	NO
5779801	22188875	AN	PLoS52	analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
5779801	22188875	MEC	PLoS52	analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
5779801	22188875	VLC	PLoS52	analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
5425610	28553310	BH	2	performed the experiments and data analysis	performed the experiments and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5425610	28553310	C-BD	2	performed the experiments and data analysis	performed the experiments and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5425610	28553310	CH	2	performed the experiments and data analysis	performed the experiments and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5425610	28553310	J-QL	2	performed the experiments and data analysis	performed the experiments and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5425610	28553310	L-JZ	2	performed the experiments and data analysis	performed the experiments and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5425610	28553310	MY	2	designed the experiments|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5425610	28553310	MY	2	designed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5425610	28553310	Q-HH	2	performed the experiments and data analysis|wrote the manuscript	performed the experiments and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5425610	28553310	Q-HH	2	performed the experiments and data analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5425610	28553310	SY	2	designed the experiments|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5425610	28553310	SY	2	designed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5425610	28553310	Y-EC	2	performed the experiments and data analysis	performed the experiments and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5425610	28553310	YH	2	performed the experiments and data analysis	performed the experiments and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5425610	28553310	Z-WZ	2	performed the experiments and data analysis	performed the experiments and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6321380	30441802	D.R.d.A.	2	contributed to the design of the experiments	contributed to the design of the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6321380	30441802	E.d.P.	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6321380	30441802	EPR	2	analgesia tests, respectively	analgesia tests, respectively	-	-	NO
6321380	30441802	L.N.M.R.	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6321380	30441802	N.D.	2	contributed to the design of the experiments	contributed to the design of the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6321380	30441802	P.S.	2	contributed to the design of the experiments	contributed to the design of the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6321380	30441802	R.d.M.B.	2	conducted all experiments|wrote the manuscript	conducted all experiments	Performed the experiments	Investigation	YES
6321380	30441802	R.d.M.B.	2	conducted all experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6321380	30441802	TEM	2	analgesia tests, respectively	analgesia tests, respectively	-	-	NO
6163291	30046022	A.S.J.C.	CRediT	Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6163291	30046022	F.A.	CRediT	Conceptualization|Writing--original draft preparation	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6163291	30046022	F.A.	CRediT	Conceptualization|Writing--original draft preparation	Writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6163291	30046022	M.A.	CRediT	Conceptualization	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6163291	30046022	P.M.	CRediT	Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
3206829	21999747	All authors	2	contributed to data analyses and to finalizing the manuscript	contributed to data analyses and to finalizing the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
3206829	21999747	DPN	2	initiated and all authors designed the study	initiated and all authors designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3206829	21999747	NIKD	2	who prepared the draft paper	who prepared the draft paper	Wrote the paper	Writing - Original Draft	YES
4397079	25875081	ALB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397079	25875081	ALB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397079	25875081	ALB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397079	25875081	CAB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397079	25875081	CAB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397079	25875081	CAB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397079	25875081	CAB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397079	25875081	MAP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397079	25875081	MAP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397079	25875081	MAP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397079	25875081	RML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397079	25875081	RML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397079	25875081	RML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397079	25875081	RML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397079	25875081	RML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397079	25875081	SAK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397079	25875081	SAK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397079	25875081	SAK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4992247	27542599	BP	2	designed the research program|performed the analyses	designed the research program	Conceived and designed the experiments	Methodology	YES
4992247	27542599	BP	2	designed the research program|performed the analyses	performed the analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4992247	27542599	FG	2	wrote the manuscript, figures, additional files and captions	wrote the manuscript, figures, additional files and captions	Wrote the paper	Visualization|Writing - Original Draft	YES
4992247	27542599	PA	2	wrote the manuscript, figures, additional files and captions	wrote the manuscript, figures, additional files and captions	Wrote the paper	Visualization|Writing - Original Draft	YES
4992247	27542599	SG	2	designed the research program|performed the analyses|wrote the manuscript, figures, additional files and captions	designed the research program	Conceived and designed the experiments	Methodology	YES
4992247	27542599	SG	2	designed the research program|performed the analyses|wrote the manuscript, figures, additional files and captions	performed the analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4992247	27542599	SG	2	designed the research program|performed the analyses|wrote the manuscript, figures, additional files and captions	wrote the manuscript, figures, additional files and captions	Wrote the paper	Visualization|Writing - Original Draft	YES
4992247	27542599	YB	2	designed the research program|performed the analyses|wrote the manuscript, figures, additional files and captions	designed the research program	Conceived and designed the experiments	Methodology	YES
4992247	27542599	YB	2	designed the research program|performed the analyses|wrote the manuscript, figures, additional files and captions	performed the analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4992247	27542599	YB	2	designed the research program|performed the analyses|wrote the manuscript, figures, additional files and captions	wrote the manuscript, figures, additional files and captions	Wrote the paper	Visualization|Writing - Original Draft	YES
5426280	28553297	CZ	2	collected the materials and measured the traits of fruit, leaf and flower	collected the materials and measured the traits of fruit, leaf and flower	Performed the experiments	Investigation	YES
5426280	28553297	DL	2	conceived and planned the study|tested the ploidy levels|wrote the manuscript	conceived and planned the study	Conceived and designed the experiments	Conceptualization	YES
5426280	28553297	DL	2	conceived and planned the study|tested the ploidy levels|wrote the manuscript	tested the ploidy levels	Performed the experiments	Investigation	YES
5426280	28553297	DL	2	conceived and planned the study|tested the ploidy levels|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5426280	28553297	QZ	2	tested the ploidy levels	tested the ploidy levels	Performed the experiments	Investigation	YES
5426280	28553297	YL	2	tested the ploidy levels	tested the ploidy levels	Performed the experiments	Investigation	YES
5426280	28553297	YZ	2	conceived and planned the study|collected the materials and measured the traits of fruit, leaf and flower	conceived and planned the study	Conceived and designed the experiments	Conceptualization	YES
5426280	28553297	YZ	2	conceived and planned the study|collected the materials and measured the traits of fruit, leaf and flower	collected the materials and measured the traits of fruit, leaf and flower	Performed the experiments	Investigation	YES
6439133	30944805	BP	2	did molecular analysis|analyzed the data and wrote the manuscript	did molecular analysis	Performed the experiments	Investigation	YES
6439133	30944805	BP	2	did molecular analysis|analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6439133	30944805	MM	2	participated in experimental design	participated in experimental design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6439133	30944805	SZ	2	did rice transformations	did rice transformations	-	-	NO
6439133	30944805	VS	2	analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4397080	25875218	BC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397080	25875218	BC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397080	25875218	BC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397080	25875218	DRR	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397080	25875218	DRR	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397080	25875218	IMC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397080	25875218	IMC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397080	25875218	IMC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397080	25875218	LAF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397080	25875218	LAF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397080	25875218	LAF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397080	25875218	LAF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397080	25875218	MJP	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397080	25875218	MJP	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5427086	28553309	BW	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5427086	28553309	FX	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5427086	28553309	JZ	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5427086	28553309	KD	PLoS52	designed the experiments|performed the experiments|wrote the manuscript text	designed the experiments	Conceived and designed the experiments	Methodology	YES
5427086	28553309	KD	PLoS52	designed the experiments|performed the experiments|wrote the manuscript text	performed the experiments	Performed the experiments	Investigation	YES
5427086	28553309	KD	PLoS52	designed the experiments|performed the experiments|wrote the manuscript text	wrote the manuscript text	Wrote the paper	Writing - Original Draft	YES
5427086	28553309	KW	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5427086	28553309	LF	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5427086	28553309	MR	PLoS52	designed the experiments|analyzed the data|wrote the manuscript text	designed the experiments	Conceived and designed the experiments	Methodology	YES
5427086	28553309	MR	PLoS52	designed the experiments|analyzed the data|wrote the manuscript text	analyzed the data	Analyzed the data	Formal analysis	YES
5427086	28553309	MR	PLoS52	designed the experiments|analyzed the data|wrote the manuscript text	wrote the manuscript text	Wrote the paper	Writing - Original Draft	YES
5427086	28553309	PD	PLoS52	analyzed the data|wrote the manuscript text	analyzed the data	Analyzed the data	Formal analysis	YES
5427086	28553309	PD	PLoS52	analyzed the data|wrote the manuscript text	wrote the manuscript text	Wrote the paper	Writing - Original Draft	YES
5427086	28553309	SF	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5427086	28553309	SZ	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5427086	28553309	WW	PLoS52	designed the experiments|performed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5427086	28553309	WW	PLoS52	designed the experiments|performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
3212809	21978386	AA	2	carried out the experimental work	carried out the experimental work	Performed the experiments	Investigation	YES
3212809	21978386	FB	2	proposed, planned and supervised the whole work	proposed, planned and supervised the whole work	Conceived and designed the experiments	Conceptualization|Supervision	YES
3212809	21978386	NME	2	designed the proposed method, analysed the data stastistically and wrote the manuscript and collect the literature review	designed the proposed method, analysed the data stastistically and wrote the manuscript and collect the literature review	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
6163461	30081504	A.B.S.	CRediT	Conceptualization|Methodology|Validation|Writing-original draft preparation|Writing-review & editing|Visualization|Supervision|Project administration	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6163461	30081504	A.B.S.	CRediT	Conceptualization|Methodology|Validation|Writing-original draft preparation|Writing-review & editing|Visualization|Supervision|Project administration	Methodology	Performed the experiments	Methodology	YES
6163461	30081504	A.B.S.	CRediT	Conceptualization|Methodology|Validation|Writing-original draft preparation|Writing-review & editing|Visualization|Supervision|Project administration	Validation	Performed the experiments	Validation	YES
6163461	30081504	A.B.S.	CRediT	Conceptualization|Methodology|Validation|Writing-original draft preparation|Writing-review & editing|Visualization|Supervision|Project administration	Writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
6163461	30081504	A.B.S.	CRediT	Conceptualization|Methodology|Validation|Writing-original draft preparation|Writing-review & editing|Visualization|Supervision|Project administration	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6163461	30081504	A.B.S.	CRediT	Conceptualization|Methodology|Validation|Writing-original draft preparation|Writing-review & editing|Visualization|Supervision|Project administration	Visualization	Analyzed the data	Visualization	YES
6163461	30081504	A.B.S.	CRediT	Conceptualization|Methodology|Validation|Writing-original draft preparation|Writing-review & editing|Visualization|Supervision|Project administration	Supervision	-	Supervision	YES
6163461	30081504	A.B.S.	CRediT	Conceptualization|Methodology|Validation|Writing-original draft preparation|Writing-review & editing|Visualization|Supervision|Project administration	Project administration	-	Project administration	YES
6163461	30081504	C.L.B.	CRediT	Validation|Resources|Writing-review & editing|Visualization|Supervision|Funding acquisition	Validation	Performed the experiments	Validation	YES
6163461	30081504	C.L.B.	CRediT	Validation|Resources|Writing-review & editing|Visualization|Supervision|Funding acquisition	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6163461	30081504	C.L.B.	CRediT	Validation|Resources|Writing-review & editing|Visualization|Supervision|Funding acquisition	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6163461	30081504	C.L.B.	CRediT	Validation|Resources|Writing-review & editing|Visualization|Supervision|Funding acquisition	Visualization	Analyzed the data	Visualization	YES
6163461	30081504	C.L.B.	CRediT	Validation|Resources|Writing-review & editing|Visualization|Supervision|Funding acquisition	Supervision	-	Supervision	YES
6163461	30081504	C.L.B.	CRediT	Validation|Resources|Writing-review & editing|Visualization|Supervision|Funding acquisition	Funding acquisition	-	Funding acquisition	YES
6163461	30081504	K.A.C.	CRediT	Conceptualization|Methodology|Validation|Writing-original draft preparation|Writing-review & editing|Visualization|Supervision	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6163461	30081504	K.A.C.	CRediT	Conceptualization|Methodology|Validation|Writing-original draft preparation|Writing-review & editing|Visualization|Supervision	Methodology	Performed the experiments	Methodology	YES
6163461	30081504	K.A.C.	CRediT	Conceptualization|Methodology|Validation|Writing-original draft preparation|Writing-review & editing|Visualization|Supervision	Validation	Performed the experiments	Validation	YES
6163461	30081504	K.A.C.	CRediT	Conceptualization|Methodology|Validation|Writing-original draft preparation|Writing-review & editing|Visualization|Supervision	Writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
6163461	30081504	K.A.C.	CRediT	Conceptualization|Methodology|Validation|Writing-original draft preparation|Writing-review & editing|Visualization|Supervision	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6163461	30081504	K.A.C.	CRediT	Conceptualization|Methodology|Validation|Writing-original draft preparation|Writing-review & editing|Visualization|Supervision	Visualization	Analyzed the data	Visualization	YES
6163461	30081504	K.A.C.	CRediT	Conceptualization|Methodology|Validation|Writing-original draft preparation|Writing-review & editing|Visualization|Supervision	Supervision	-	Supervision	YES
6163461	30081504	S.R.	CRediT	Methodology|Formal analysis|Investigation|Data curation|Writing-original draft preparation|Writing-review & editing|Visualization	Methodology	Performed the experiments	Methodology	YES
6163461	30081504	S.R.	CRediT	Methodology|Formal analysis|Investigation|Data curation|Writing-original draft preparation|Writing-review & editing|Visualization	Formal analysis	Analyzed the data	Formal analysis	YES
6163461	30081504	S.R.	CRediT	Methodology|Formal analysis|Investigation|Data curation|Writing-original draft preparation|Writing-review & editing|Visualization	Investigation	Performed the experiments	Investigation	YES
6163461	30081504	S.R.	CRediT	Methodology|Formal analysis|Investigation|Data curation|Writing-original draft preparation|Writing-review & editing|Visualization	Data curation	Analyzed the data	Data curation	YES
6163461	30081504	S.R.	CRediT	Methodology|Formal analysis|Investigation|Data curation|Writing-original draft preparation|Writing-review & editing|Visualization	Writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
6163461	30081504	S.R.	CRediT	Methodology|Formal analysis|Investigation|Data curation|Writing-original draft preparation|Writing-review & editing|Visualization	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6163461	30081504	S.R.	CRediT	Methodology|Formal analysis|Investigation|Data curation|Writing-original draft preparation|Writing-review & editing|Visualization	Visualization	Analyzed the data	Visualization	YES
6321408	30572649	C.G.	CRediT	methodology|validation|supervision	methodology	Performed the experiments	Methodology	YES
6321408	30572649	C.G.	CRediT	methodology|validation|supervision	validation	Performed the experiments	Validation	YES
6321408	30572649	C.G.	CRediT	methodology|validation|supervision	supervision	-	Supervision	YES
6321408	30572649	F.M.	CRediT	formal analysis|data curation|writing--review and editing	formal analysis	Analyzed the data	Formal analysis	YES
6321408	30572649	F.M.	CRediT	formal analysis|data curation|writing--review and editing	data curation	Analyzed the data	Data curation	YES
6321408	30572649	F.M.	CRediT	formal analysis|data curation|writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6321408	30572649	L.D.C.M.	CRediT	software|validation|visualization	software	Contributed reagents/materials/analysis tools	Software	YES
6321408	30572649	L.D.C.M.	CRediT	software|validation|visualization	validation	Performed the experiments	Validation	YES
6321408	30572649	L.D.C.M.	CRediT	software|validation|visualization	visualization	Analyzed the data	Visualization	YES
6321408	30572649	M.C.	CRediT	Conceptualization|investigation|writing--original draft preparation	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6321408	30572649	M.C.	CRediT	Conceptualization|investigation|writing--original draft preparation	investigation	Performed the experiments	Investigation	YES
6321408	30572649	M.C.	CRediT	Conceptualization|investigation|writing--original draft preparation	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6321408	30572649	P.M.	CRediT	Conceptualization|methodology|software|validation|resources|project administration|funding acquisition	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6321408	30572649	P.M.	CRediT	Conceptualization|methodology|software|validation|resources|project administration|funding acquisition	methodology	Performed the experiments	Methodology	YES
6321408	30572649	P.M.	CRediT	Conceptualization|methodology|software|validation|resources|project administration|funding acquisition	software	Contributed reagents/materials/analysis tools	Software	YES
6321408	30572649	P.M.	CRediT	Conceptualization|methodology|software|validation|resources|project administration|funding acquisition	validation	Performed the experiments	Validation	YES
6321408	30572649	P.M.	CRediT	Conceptualization|methodology|software|validation|resources|project administration|funding acquisition	resources	Contributed reagents/materials/analysis tools	Resources	YES
6321408	30572649	P.M.	CRediT	Conceptualization|methodology|software|validation|resources|project administration|funding acquisition	project administration	-	Project administration	YES
6321408	30572649	P.M.	CRediT	Conceptualization|methodology|software|validation|resources|project administration|funding acquisition	funding acquisition	-	Funding acquisition	YES
3212923	21982201	DDQ	2	charge-transfer complex	charge-transfer complex	-	-	NO
3212923	21982201	ID	2	designed the study, participated in the results discussion and prepared the manuscript	designed the study, participated in the results discussion and prepared the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3212923	21982201	NK	2	participated in the assay design and conducted the assay validation and analysis of dosage forms	participated in the assay design and conducted the assay validation and analysis of dosage forms	Conceived and designed the experiments|Performed the experiments	Investigation|Validation	YES
3212923	21982201	TW	2	participated in the design of the study and conducting the optimization of the assay conditions and validation	participated in the design of the study and conducting the optimization of the assay conditions and validation	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Validation	YES
4476998	25896304	A.P.	2	was involved in designing the research, pathology analysis, and analysis of results and wrote the manuscript	was involved in designing the research, pathology analysis, and analysis of results and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4476998	25896304	B.K.M.	2	was involved in designing the research and analysis of results and wrote the manuscript	was involved in designing the research and analysis of results and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4476998	25896304	D.S.	2	analyzed the results, provided technical advice, and wrote the manuscript	analyzed the results, provided technical advice, and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4476998	25896304	L.F.	2	performed research studies and analyzed the results	performed research studies and analyzed the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4476998	25896304	M.H.	2	provided intellectual contribution and technical advice	provided intellectual contribution and technical advice	-	-	NO
4476998	25896304	M.J.L.	2	performed research studies and analyzed the results	performed research studies and analyzed the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4476998	25896304	P.B.	2	designed the research, performed research studies, analyzed the results, made the figures, and wrote the manuscript	designed the research, performed research studies, analyzed the results, made the figures, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Visualization|Writing - Original Draft	YES
4992253	27543050	BRS	2	performed bioinformatic analyses and wrote the manuscript	performed bioinformatic analyses and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4992253	27543050	EVR	2	performed ms experiments and analysis and wrote the manuscript	performed ms experiments and analysis and wrote the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4992253	27543050	ISH	2	experiments, and bioinformatic analyses, and wrote the manuscript	experiments, and bioinformatic analyses, and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4992253	27543050	JVS	2	contributed to experimental design, data analysis, and wrote the manuscript	contributed to experimental design, data analysis, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
4992253	27543050	KPM	2	performed ish experiments and analysis and wrote the manuscript	performed ish experiments and analysis and wrote the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4992253	27543050	RDF	2	contributed to experimental design, data analysis, and wrote the manuscript	contributed to experimental design, data analysis, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
4397082	25875528	ALB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397082	25875528	ALB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397082	25875528	ALB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397082	25875528	CBJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397082	25875528	CBJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397082	25875528	CBJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397082	25875528	CBJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397082	25875528	PJAD	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397082	25875528	PJAD	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397082	25875528	PJAD	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397082	25875528	RWB	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397082	25875528	RWB	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397082	25875528	RWB	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397082	25875528	TK	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397082	25875528	TK	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5427108	28553299	BirAG	2	function in rice protoplasts and protein identification	function in rice protoplasts and protein identification	Performed the experiments	Investigation	YES
5427108	28553299	HL	2	designed and carried out the project|wrote the manuscript	designed and carried out the project	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5427108	28553299	HL	2	designed and carried out the project|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5427108	28553299	MF	2	performed gene cloning and rice protoplasts transformation	performed gene cloning and rice protoplasts transformation	Performed the experiments	Investigation	YES
5427108	28553299	ML	2	directed the study|wrote the manuscript	directed the study	-	Supervision	YES
5427108	28553299	ML	2	directed the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5427108	28553299	WL	2	performed gene cloning and rice protoplasts transformation	performed gene cloning and rice protoplasts transformation	Performed the experiments	Investigation	YES
5427108	28553299	ZZ	2	performed the bifc analysis	performed the bifc analysis	Performed the experiments	Investigation	YES
6163507	30200574	J.F.C.	CRediT	Validation	Validation	Performed the experiments	Validation	YES
6163507	30200574	M.S.	CRediT	Conceptualization|Writing-original draft preparation|Visualization	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6163507	30200574	M.S.	CRediT	Conceptualization|Writing-original draft preparation|Visualization	Writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
6163507	30200574	M.S.	CRediT	Conceptualization|Writing-original draft preparation|Visualization	Visualization	Analyzed the data	Visualization	YES
6163507	30200574	M.W.	CRediT	Resources	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6163507	30200574	T.G.D.	CRediT	Conceptualization|Methodology|Validation|Investigation|Writing-review & editing|Supervision|Project administration	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6163507	30200574	T.G.D.	CRediT	Conceptualization|Methodology|Validation|Investigation|Writing-review & editing|Supervision|Project administration	Methodology	Performed the experiments	Methodology	YES
6163507	30200574	T.G.D.	CRediT	Conceptualization|Methodology|Validation|Investigation|Writing-review & editing|Supervision|Project administration	Validation	Performed the experiments	Validation	YES
6163507	30200574	T.G.D.	CRediT	Conceptualization|Methodology|Validation|Investigation|Writing-review & editing|Supervision|Project administration	Investigation	Performed the experiments	Investigation	YES
6163507	30200574	T.G.D.	CRediT	Conceptualization|Methodology|Validation|Investigation|Writing-review & editing|Supervision|Project administration	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6163507	30200574	T.G.D.	CRediT	Conceptualization|Methodology|Validation|Investigation|Writing-review & editing|Supervision|Project administration	Supervision	-	Supervision	YES
6163507	30200574	T.G.D.	CRediT	Conceptualization|Methodology|Validation|Investigation|Writing-review & editing|Supervision|Project administration	Project administration	-	Project administration	YES
6321412	30241371	A.O.	CRediT	Software|Validation	Software	Contributed reagents/materials/analysis tools	Software	YES
6321412	30241371	A.O.	CRediT	Software|Validation	Validation	Performed the experiments	Validation	YES
6321412	30241371	C.Y.	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
6321412	30241371	H.T.	CRediT	Conceptualization|Methodology|Writing-original draft preparation|Writing-review & editing|Funding acquisition	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6321412	30241371	H.T.	CRediT	Conceptualization|Methodology|Writing-original draft preparation|Writing-review & editing|Funding acquisition	Methodology	Performed the experiments	Methodology	YES
6321412	30241371	H.T.	CRediT	Conceptualization|Methodology|Writing-original draft preparation|Writing-review & editing|Funding acquisition	Writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
6321412	30241371	H.T.	CRediT	Conceptualization|Methodology|Writing-original draft preparation|Writing-review & editing|Funding acquisition	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6321412	30241371	H.T.	CRediT	Conceptualization|Methodology|Writing-original draft preparation|Writing-review & editing|Funding acquisition	Funding acquisition	-	Funding acquisition	YES
6321412	30241371	K.S.	CRediT	Conceptualization|Writing-review & editing|Supervision|Funding acquisition	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6321412	30241371	K.S.	CRediT	Conceptualization|Writing-review & editing|Supervision|Funding acquisition	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6321412	30241371	K.S.	CRediT	Conceptualization|Writing-review & editing|Supervision|Funding acquisition	Supervision	-	Supervision	YES
6321412	30241371	K.S.	CRediT	Conceptualization|Writing-review & editing|Supervision|Funding acquisition	Funding acquisition	-	Funding acquisition	YES
6321412	30241371	M.F.	CRediT	Software|Validation|Visualization	Software	Contributed reagents/materials/analysis tools	Software	YES
6321412	30241371	M.F.	CRediT	Software|Validation|Visualization	Validation	Performed the experiments	Validation	YES
6321412	30241371	M.F.	CRediT	Software|Validation|Visualization	Visualization	Analyzed the data	Visualization	YES
6321412	30241371	S.D.	CRediT	Methodology|Software|Investigation|Data curation|Writing-original draft preparation|Writing-review & editing	Methodology	Performed the experiments	Methodology	YES
6321412	30241371	S.D.	CRediT	Methodology|Software|Investigation|Data curation|Writing-original draft preparation|Writing-review & editing	Software	Contributed reagents/materials/analysis tools	Software	YES
6321412	30241371	S.D.	CRediT	Methodology|Software|Investigation|Data curation|Writing-original draft preparation|Writing-review & editing	Investigation	Performed the experiments	Investigation	YES
6321412	30241371	S.D.	CRediT	Methodology|Software|Investigation|Data curation|Writing-original draft preparation|Writing-review & editing	Data curation	Analyzed the data	Data curation	YES
6321412	30241371	S.D.	CRediT	Methodology|Software|Investigation|Data curation|Writing-original draft preparation|Writing-review & editing	Writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
6321412	30241371	S.D.	CRediT	Methodology|Software|Investigation|Data curation|Writing-original draft preparation|Writing-review & editing	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
3215931	21917164	DAS	2	directing research and preparing the draft manuscript	directing research and preparing the draft manuscript	Wrote the paper	Writing - Original Draft	YES
3215931	21917164	SCB	2	collecting, reviewing and organizing data	collecting, reviewing and organizing data	Performed the experiments	Investigation	YES
3215931	21917164	WJH	2	designed the experiment and prepared the final paper	designed the experiment and prepared the final paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3223136	22059735	FFB	2	proposed, planned and supervised the whole work	proposed, planned and supervised the whole work	Conceived and designed the experiments	Conceptualization|Supervision	YES
3223136	22059735	MHE	2	carried out the experimental work	carried out the experimental work	Performed the experiments	Investigation	YES
3223136	22059735	MIW	2	designed the proposed method and analyzed the data statistically	designed the proposed method and analyzed the data statistically	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
3223136	22059735	NME	2	coordinated the study and modified the text	coordinated the study and modified the text	-	Project administration	YES
6163595	30011814	B.D.F.	CRediT	Methodology|Resources|Writing--review & editing	Methodology	Performed the experiments	Methodology	YES
6163595	30011814	B.D.F.	CRediT	Methodology|Resources|Writing--review & editing	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6163595	30011814	B.D.F.	CRediT	Methodology|Resources|Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6163595	30011814	C.A.S.	CRediT	Data curation|Investigation|Methodology|Resources|Writing--review & editing	Data curation	Analyzed the data	Data curation	YES
6163595	30011814	C.A.S.	CRediT	Data curation|Investigation|Methodology|Resources|Writing--review & editing	Investigation	Performed the experiments	Investigation	YES
6163595	30011814	C.A.S.	CRediT	Data curation|Investigation|Methodology|Resources|Writing--review & editing	Methodology	Performed the experiments	Methodology	YES
6163595	30011814	C.A.S.	CRediT	Data curation|Investigation|Methodology|Resources|Writing--review & editing	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6163595	30011814	C.A.S.	CRediT	Data curation|Investigation|Methodology|Resources|Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6163595	30011814	C.T.B.	CRediT	Data curation|Investigation|Writing--review & editing	Data curation	Analyzed the data	Data curation	YES
6163595	30011814	C.T.B.	CRediT	Data curation|Investigation|Writing--review & editing	Investigation	Performed the experiments	Investigation	YES
6163595	30011814	C.T.B.	CRediT	Data curation|Investigation|Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6163595	30011814	G.R.	CRediT	Data curation|Investigation|Methodology|Resources|Software|Writing--review & editing	Data curation	Analyzed the data	Data curation	YES
6163595	30011814	G.R.	CRediT	Data curation|Investigation|Methodology|Resources|Software|Writing--review & editing	Investigation	Performed the experiments	Investigation	YES
6163595	30011814	G.R.	CRediT	Data curation|Investigation|Methodology|Resources|Software|Writing--review & editing	Methodology	Performed the experiments	Methodology	YES
6163595	30011814	G.R.	CRediT	Data curation|Investigation|Methodology|Resources|Software|Writing--review & editing	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6163595	30011814	G.R.	CRediT	Data curation|Investigation|Methodology|Resources|Software|Writing--review & editing	Software	Contributed reagents/materials/analysis tools	Software	YES
6163595	30011814	G.R.	CRediT	Data curation|Investigation|Methodology|Resources|Software|Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6163595	30011814	J.L.	CRediT	Investigation|Methodology|Writing--review & editing	Investigation	Performed the experiments	Investigation	YES
6163595	30011814	J.L.	CRediT	Investigation|Methodology|Writing--review & editing	Methodology	Performed the experiments	Methodology	YES
6163595	30011814	J.L.	CRediT	Investigation|Methodology|Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6163595	30011814	M.P.S.	CRediT	Data curation|Investigation|Methodology|Writing--review & editing	Data curation	Analyzed the data	Data curation	YES
6163595	30011814	M.P.S.	CRediT	Data curation|Investigation|Methodology|Writing--review & editing	Investigation	Performed the experiments	Investigation	YES
6163595	30011814	M.P.S.	CRediT	Data curation|Investigation|Methodology|Writing--review & editing	Methodology	Performed the experiments	Methodology	YES
6163595	30011814	M.P.S.	CRediT	Data curation|Investigation|Methodology|Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6163595	30011814	M.S.	CRediT	Methodology|Resources|Writing--review & editing	Methodology	Performed the experiments	Methodology	YES
6163595	30011814	M.S.	CRediT	Methodology|Resources|Writing--review & editing	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6163595	30011814	M.S.	CRediT	Methodology|Resources|Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6163595	30011814	M.T.B.	CRediT	Funding acquisition|Methodology|Resources|Writing--review & editing	Funding acquisition	-	Funding acquisition	YES
6163595	30011814	M.T.B.	CRediT	Funding acquisition|Methodology|Resources|Writing--review & editing	Methodology	Performed the experiments	Methodology	YES
6163595	30011814	M.T.B.	CRediT	Funding acquisition|Methodology|Resources|Writing--review & editing	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6163595	30011814	M.T.B.	CRediT	Funding acquisition|Methodology|Resources|Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6163595	30011814	P.H.	CRediT	Data curation|Investigation|Writing--review & editing	Data curation	Analyzed the data	Data curation	YES
6163595	30011814	P.H.	CRediT	Data curation|Investigation|Writing--review & editing	Investigation	Performed the experiments	Investigation	YES
6163595	30011814	P.H.	CRediT	Data curation|Investigation|Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6163595	30011814	R.N.H.	CRediT	Conceptualization|Funding acquisition|Methodology|Project administration|Resources|Supervision|Writing--review & editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6163595	30011814	R.N.H.	CRediT	Conceptualization|Funding acquisition|Methodology|Project administration|Resources|Supervision|Writing--review & editing	Funding acquisition	-	Funding acquisition	YES
6163595	30011814	R.N.H.	CRediT	Conceptualization|Funding acquisition|Methodology|Project administration|Resources|Supervision|Writing--review & editing	Methodology	Performed the experiments	Methodology	YES
6163595	30011814	R.N.H.	CRediT	Conceptualization|Funding acquisition|Methodology|Project administration|Resources|Supervision|Writing--review & editing	Project administration	-	Project administration	YES
6163595	30011814	R.N.H.	CRediT	Conceptualization|Funding acquisition|Methodology|Project administration|Resources|Supervision|Writing--review & editing	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6163595	30011814	R.N.H.	CRediT	Conceptualization|Funding acquisition|Methodology|Project administration|Resources|Supervision|Writing--review & editing	Supervision	-	Supervision	YES
6163595	30011814	R.N.H.	CRediT	Conceptualization|Funding acquisition|Methodology|Project administration|Resources|Supervision|Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6163595	30011814	S.S.S.	CRediT	Methodology|Resources|Writing--review & editing	Methodology	Performed the experiments	Methodology	YES
6163595	30011814	S.S.S.	CRediT	Methodology|Resources|Writing--review & editing	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6163595	30011814	S.S.S.	CRediT	Methodology|Resources|Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6163595	30011814	Z.H.	CRediT	Data curation|Investigation|Methodology|Writing--review & editing	Data curation	Analyzed the data	Data curation	YES
6163595	30011814	Z.H.	CRediT	Data curation|Investigation|Methodology|Writing--review & editing	Investigation	Performed the experiments	Investigation	YES
6163595	30011814	Z.H.	CRediT	Data curation|Investigation|Methodology|Writing--review & editing	Methodology	Performed the experiments	Methodology	YES
6163595	30011814	Z.H.	CRediT	Data curation|Investigation|Methodology|Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
4390612	25883941	All authors	2	approved the final version of the paper	approved the final version of the paper	-	-	NO
4390612	25883941	Martin Canis	2	contributed equally to this work	contributed equally to this work	-	-	NO
4390612	25883941	Steffen Dietzel	2	contributed equally to this work	contributed equally to this work	-	-	NO
5427111	28553304	AT	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5427111	28553304	HC	PLoS52	performed the experiments|prepared reagents/materials	performed the experiments	Performed the experiments	Investigation	YES
5427111	28553304	HC	PLoS52	performed the experiments|prepared reagents/materials	prepared reagents/materials	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5427111	28553304	JQ	PLoS52	initiated and designed the research|revised paper	initiated and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5427111	28553304	JQ	PLoS52	initiated and designed the research|revised paper	revised paper	Wrote the paper	Writing - Review & Editing	YES
5427111	28553304	JX	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5427111	28553304	MC	PLoS52	performed the experiments|prepared reagents/materials	performed the experiments	Performed the experiments	Investigation	YES
5427111	28553304	MC	PLoS52	performed the experiments|prepared reagents/materials	prepared reagents/materials	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5427111	28553304	The authors	PLoS52	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	Performed the experiments	Investigation	YES
5427111	28553304	XH	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5427111	28553304	XN	PLoS52	initiated and designed the research|performed the experiments|analyzed the data|prepared reagents/materials|wrote the paper|revised paper	initiated and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5427111	28553304	XN	PLoS52	initiated and designed the research|performed the experiments|analyzed the data|prepared reagents/materials|wrote the paper|revised paper	performed the experiments	Performed the experiments	Investigation	YES
5427111	28553304	XN	PLoS52	initiated and designed the research|performed the experiments|analyzed the data|prepared reagents/materials|wrote the paper|revised paper	analyzed the data	Analyzed the data	Formal analysis	YES
5427111	28553304	XN	PLoS52	initiated and designed the research|performed the experiments|analyzed the data|prepared reagents/materials|wrote the paper|revised paper	prepared reagents/materials	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5427111	28553304	XN	PLoS52	initiated and designed the research|performed the experiments|analyzed the data|prepared reagents/materials|wrote the paper|revised paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5427111	28553304	XN	PLoS52	initiated and designed the research|performed the experiments|analyzed the data|prepared reagents/materials|wrote the paper|revised paper	revised paper	Wrote the paper	Writing - Review & Editing	YES
4397083	25875836	BM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397083	25875836	BM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397083	25875836	BM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397083	25875836	KK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397083	25875836	KK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397083	25875836	KK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397083	25875836	KK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397083	25875836	RD	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397083	25875836	RD	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397083	25875836	SK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397083	25875836	SK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397083	25875836	SK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397083	25875836	SP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397083	25875836	SP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397083	25875836	SP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397083	25875836	SP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397083	25875836	TS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397083	25875836	TS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397083	25875836	TS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397083	25875836	UW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397083	25875836	UW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397083	25875836	UW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397083	25875836	UW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397083	25875836	UW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4992267	27542721	LES	PLoS52	performed the laboratory experiments	performed the laboratory experiments	Performed the experiments	Investigation	YES
4992267	27542721	NB	PLoS52	conceived and designed the experiment|wrote the manuscript	conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
4992267	27542721	NB	PLoS52	conceived and designed the experiment|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4992267	27542721	RB	PLoS52	analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
4992267	27542721	RB	PLoS52	analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4992267	27542721	SS	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
4992267	27542721	VRM	PLoS52	performed the laboratory experiments	performed the laboratory experiments	Performed the experiments	Investigation	YES
3226436	22067118	BL	2	conceived of the study and its design and coordination of the scientific teams	conceived of the study and its design and coordination of the scientific teams	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
3226436	22067118	SW	2	carried out the chemical and biological studies	carried out the chemical and biological studies	Performed the experiments	Investigation	YES
6321429	30513738	C.W.	CRediT	Funding acquisition|Supervision	Funding acquisition	-	Funding acquisition	YES
6321429	30513738	C.W.	CRediT	Funding acquisition|Supervision	Supervision	-	Supervision	YES
6321429	30513738	G.W.	CRediT	Methodology	Methodology	Performed the experiments	Methodology	YES
6321429	30513738	H.J.	CRediT	Data curation	Data curation	Analyzed the data	Data curation	YES
6321429	30513738	S.C.	CRediT	Methodology	Methodology	Performed the experiments	Methodology	YES
6321429	30513738	W.W.	CRediT	Conceptualization	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6321429	30513738	X.P.	CRediT	Supervision	Supervision	-	Supervision	YES
6321429	30513738	X.Z.	CRediT	Conceptualization|Data curation|Writing--review and editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6321429	30513738	X.Z.	CRediT	Conceptualization|Data curation|Writing--review and editing	Data curation	Analyzed the data	Data curation	YES
6321429	30513738	X.Z.	CRediT	Conceptualization|Data curation|Writing--review and editing	Writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6321429	30513738	Y.C.	CRediT	Conceptualization|Data curation|Writing--original draft	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6321429	30513738	Y.C.	CRediT	Conceptualization|Data curation|Writing--original draft	Data curation	Analyzed the data	Data curation	YES
6321429	30513738	Y.C.	CRediT	Conceptualization|Data curation|Writing--original draft	Writing--original draft	Wrote the paper	Writing - Original Draft	YES
6321429	30513738	Y.H.	CRediT	Funding acquisition|Writing--review and editing	Funding acquisition	-	Funding acquisition	YES
6321429	30513738	Y.H.	CRediT	Funding acquisition|Writing--review and editing	Writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6321429	30513738	Z.H.	CRediT	Writing--review and editing	Writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6321429	30513738	Z.Z.	CRediT	Methodology	Methodology	Performed the experiments	Methodology	YES
5779808	22118532	AM	2	assisted with the study design, data collection, analysis, interpretation and writing of the manuscript	assisted with the study design, data collection, analysis, interpretation and writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5779808	22118532	GDS	2	conceived and designed the epidemiological study, gathered the initial data, assisted in the analysis, and wrote the first draft of the manuscript	conceived and designed the epidemiological study, gathered the initial data, assisted in the analysis, and wrote the first draft of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5779808	22118532	JB	2	assisted with the study design, data collection, analysis, interpretation and writing of the manuscript	assisted with the study design, data collection, analysis, interpretation and writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5779808	22118532	MW	2	assisted with the study design, data collection, analysis, interpretation and writing of the manuscript	assisted with the study design, data collection, analysis, interpretation and writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
6321434	30544966	A.M.G.	2	wrote the manuscript and contributed in conceptualization of the work|provided ideas and critically edited the entire composition of the manuscript	wrote the manuscript and contributed in conceptualization of the work	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
6321434	30544966	A.M.G.	2	wrote the manuscript and contributed in conceptualization of the work|provided ideas and critically edited the entire composition of the manuscript	provided ideas and critically edited the entire composition of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
6321434	30544966	A.V.	2	wrote the manuscript and contributed in conceptualization of the work|provided ideas and critically edited the entire composition of the manuscript	wrote the manuscript and contributed in conceptualization of the work	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
6321434	30544966	A.V.	2	wrote the manuscript and contributed in conceptualization of the work|provided ideas and critically edited the entire composition of the manuscript	provided ideas and critically edited the entire composition of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
6321434	30544966	C.C.	2	wrote the manuscript and contributed in conceptualization of the work|provided ideas and critically edited the entire composition of the manuscript	wrote the manuscript and contributed in conceptualization of the work	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
6321434	30544966	C.C.	2	wrote the manuscript and contributed in conceptualization of the work|provided ideas and critically edited the entire composition of the manuscript	provided ideas and critically edited the entire composition of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
6321434	30544966	D.M.T.	2	wrote the manuscript and contributed in conceptualization of the work|provided ideas and critically edited the entire composition of the manuscript	wrote the manuscript and contributed in conceptualization of the work	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
6321434	30544966	D.M.T.	2	wrote the manuscript and contributed in conceptualization of the work|provided ideas and critically edited the entire composition of the manuscript	provided ideas and critically edited the entire composition of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
6321434	30544966	R.I.T.	2	wrote the manuscript and contributed in conceptualization of the work|provided ideas and critically edited the entire composition of the manuscript	wrote the manuscript and contributed in conceptualization of the work	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
6321434	30544966	R.I.T.	2	wrote the manuscript and contributed in conceptualization of the work|provided ideas and critically edited the entire composition of the manuscript	provided ideas and critically edited the entire composition of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
6163692	30227643	A.B.	2	conceived and wrote the manuscript	conceived and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
6163692	30227643	J.I.	2	conceived and wrote the manuscript	conceived and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
6163692	30227643	Z.J.	2	collected materials and edited the manuscript	collected materials and edited the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
6163809	30200288	C.C.O.	CRediT	Conceptualization|Writing-review & editing|Visualization|Supervision	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6163809	30200288	C.C.O.	CRediT	Conceptualization|Writing-review & editing|Visualization|Supervision	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6163809	30200288	C.C.O.	CRediT	Conceptualization|Writing-review & editing|Visualization|Supervision	Visualization	Analyzed the data	Visualization	YES
6163809	30200288	C.C.O.	CRediT	Conceptualization|Writing-review & editing|Visualization|Supervision	Supervision	-	Supervision	YES
6163809	30200288	D.Z.O.	CRediT	Conceptualization|Writing-original draft preparation|Writing-review & editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6163809	30200288	D.Z.O.	CRediT	Conceptualization|Writing-original draft preparation|Writing-review & editing	Writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
6163809	30200288	D.Z.O.	CRediT	Conceptualization|Writing-original draft preparation|Writing-review & editing	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6163809	30200288	L.P.	CRediT	Visualization|Supervision	Visualization	Analyzed the data	Visualization	YES
6163809	30200288	L.P.	CRediT	Visualization|Supervision	Supervision	-	Supervision	YES
4397085	25874449	DFG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397085	25874449	DFG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397085	25874449	DFG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397085	25874449	DFG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397085	25874449	GHH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4397085	25874449	GY	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4397085	25874449	NN	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397085	25874449	NN	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397085	25874449	XD	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397085	25874449	XLN	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397085	25874449	ZM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4397085	25874449	ZWL	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4992276	27544903	AR	2	carried out the bioinformatic analysis of the data and wrote the paper	carried out the bioinformatic analysis of the data and wrote the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4992276	27544903	AS-C	2	prepared the biological material for chip-seq	prepared the biological material for chip-seq	Performed the experiments	Investigation	YES
4992276	27544903	JA	2	carried out the bioinformatic analysis of the data and wrote the paper|also designed and supervised the project	carried out the bioinformatic analysis of the data and wrote the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4992276	27544903	JA	2	carried out the bioinformatic analysis of the data and wrote the paper|also designed and supervised the project	also designed and supervised the project	Conceived and designed the experiments	Methodology|Supervision	YES
4992276	27544903	SP	2	prepared the biological material for chip-seq	prepared the biological material for chip-seq	Performed the experiments	Investigation	YES
6321437	30275413	A.N.K.	CRediT	Formal analysis|Investigation|Software|Writing-review & editing	Formal analysis	Analyzed the data	Formal analysis	YES
6321437	30275413	A.N.K.	CRediT	Formal analysis|Investigation|Software|Writing-review & editing	Investigation	Performed the experiments	Investigation	YES
6321437	30275413	A.N.K.	CRediT	Formal analysis|Investigation|Software|Writing-review & editing	Software	Contributed reagents/materials/analysis tools	Software	YES
6321437	30275413	A.N.K.	CRediT	Formal analysis|Investigation|Software|Writing-review & editing	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6321437	30275413	C.L.	CRediT	Data curation|Formal analysis|Writing-review & editing	Data curation	Analyzed the data	Data curation	YES
6321437	30275413	C.L.	CRediT	Data curation|Formal analysis|Writing-review & editing	Formal analysis	Analyzed the data	Formal analysis	YES
6321437	30275413	C.L.	CRediT	Data curation|Formal analysis|Writing-review & editing	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6321437	30275413	C.W.P.	CRediT	Funding acquisition|Project administration|Resources|Validation|Writing-review & editing	Funding acquisition	-	Funding acquisition	YES
6321437	30275413	C.W.P.	CRediT	Funding acquisition|Project administration|Resources|Validation|Writing-review & editing	Project administration	-	Project administration	YES
6321437	30275413	C.W.P.	CRediT	Funding acquisition|Project administration|Resources|Validation|Writing-review & editing	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6321437	30275413	C.W.P.	CRediT	Funding acquisition|Project administration|Resources|Validation|Writing-review & editing	Validation	Performed the experiments	Validation	YES
6321437	30275413	C.W.P.	CRediT	Funding acquisition|Project administration|Resources|Validation|Writing-review & editing	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6321437	30275413	H.C.R.	CRediT	Funding acquisition|Investigation	Funding acquisition	-	Funding acquisition	YES
6321437	30275413	H.C.R.	CRediT	Funding acquisition|Investigation	Investigation	Performed the experiments	Investigation	YES
6321437	30275413	J.-H.A.	CRediT	Conceptualization|Data curation|Formal analysis|Investigation|Methodology|Project administration|Software|Supervision|Writing-original draft|Writing-review & editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6321437	30275413	J.-H.A.	CRediT	Conceptualization|Data curation|Formal analysis|Investigation|Methodology|Project administration|Software|Supervision|Writing-original draft|Writing-review & editing	Data curation	Analyzed the data	Data curation	YES
6321437	30275413	J.-H.A.	CRediT	Conceptualization|Data curation|Formal analysis|Investigation|Methodology|Project administration|Software|Supervision|Writing-original draft|Writing-review & editing	Formal analysis	Analyzed the data	Formal analysis	YES
6321437	30275413	J.-H.A.	CRediT	Conceptualization|Data curation|Formal analysis|Investigation|Methodology|Project administration|Software|Supervision|Writing-original draft|Writing-review & editing	Investigation	Performed the experiments	Investigation	YES
6321437	30275413	J.-H.A.	CRediT	Conceptualization|Data curation|Formal analysis|Investigation|Methodology|Project administration|Software|Supervision|Writing-original draft|Writing-review & editing	Methodology	Performed the experiments	Methodology	YES
6321437	30275413	J.-H.A.	CRediT	Conceptualization|Data curation|Formal analysis|Investigation|Methodology|Project administration|Software|Supervision|Writing-original draft|Writing-review & editing	Project administration	-	Project administration	YES
6321437	30275413	J.-H.A.	CRediT	Conceptualization|Data curation|Formal analysis|Investigation|Methodology|Project administration|Software|Supervision|Writing-original draft|Writing-review & editing	Software	Contributed reagents/materials/analysis tools	Software	YES
6321437	30275413	J.-H.A.	CRediT	Conceptualization|Data curation|Formal analysis|Investigation|Methodology|Project administration|Software|Supervision|Writing-original draft|Writing-review & editing	Supervision	-	Supervision	YES
6321437	30275413	J.-H.A.	CRediT	Conceptualization|Data curation|Formal analysis|Investigation|Methodology|Project administration|Software|Supervision|Writing-original draft|Writing-review & editing	Writing-original draft	Wrote the paper	Writing - Original Draft	YES
6321437	30275413	J.-H.A.	CRediT	Conceptualization|Data curation|Formal analysis|Investigation|Methodology|Project administration|Software|Supervision|Writing-original draft|Writing-review & editing	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6321437	30275413	J.S.K.	CRediT	Funding acquisition|Investigation	Funding acquisition	-	Funding acquisition	YES
6321437	30275413	J.S.K.	CRediT	Funding acquisition|Investigation	Investigation	Performed the experiments	Investigation	YES
6321437	30275413	K.J.	CRediT	Funding acquisition|Methodology|Resources|Supervision|Validation|Writing-review & editing	Funding acquisition	-	Funding acquisition	YES
6321437	30275413	K.J.	CRediT	Funding acquisition|Methodology|Resources|Supervision|Validation|Writing-review & editing	Methodology	Performed the experiments	Methodology	YES
6321437	30275413	K.J.	CRediT	Funding acquisition|Methodology|Resources|Supervision|Validation|Writing-review & editing	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6321437	30275413	K.J.	CRediT	Funding acquisition|Methodology|Resources|Supervision|Validation|Writing-review & editing	Supervision	-	Supervision	YES
6321437	30275413	K.J.	CRediT	Funding acquisition|Methodology|Resources|Supervision|Validation|Writing-review & editing	Validation	Performed the experiments	Validation	YES
6321437	30275413	K.J.	CRediT	Funding acquisition|Methodology|Resources|Supervision|Validation|Writing-review & editing	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6321437	30275413	M.P.	CRediT	Data curation|Formal analysis|Investigation|Writing-review & editing	Data curation	Analyzed the data	Data curation	YES
6321437	30275413	M.P.	CRediT	Data curation|Formal analysis|Investigation|Writing-review & editing	Formal analysis	Analyzed the data	Formal analysis	YES
6321437	30275413	M.P.	CRediT	Data curation|Formal analysis|Investigation|Writing-review & editing	Investigation	Performed the experiments	Investigation	YES
6321437	30275413	M.P.	CRediT	Data curation|Formal analysis|Investigation|Writing-review & editing	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6321437	30275413	W.Y.	CRediT	Conceptualization|Data curation|Formal analysis|Investigation|Writing-original draft	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6321437	30275413	W.Y.	CRediT	Conceptualization|Data curation|Formal analysis|Investigation|Writing-original draft	Data curation	Analyzed the data	Data curation	YES
6321437	30275413	W.Y.	CRediT	Conceptualization|Data curation|Formal analysis|Investigation|Writing-original draft	Formal analysis	Analyzed the data	Formal analysis	YES
6321437	30275413	W.Y.	CRediT	Conceptualization|Data curation|Formal analysis|Investigation|Writing-original draft	Investigation	Performed the experiments	Investigation	YES
6321437	30275413	W.Y.	CRediT	Conceptualization|Data curation|Formal analysis|Investigation|Writing-original draft	Writing-original draft	Wrote the paper	Writing - Original Draft	YES
6321437	30275413	Y.-G.S.	CRediT	Project administration	Project administration	-	Project administration	YES
3236305	22047220	DS	2	assisted in the fischer-tropsch reaction study	assisted in the fischer-tropsch reaction study	-	-	NO
3236305	22047220	NAMZ	2	participated in the conception, design of study and revision of the manuscript	participated in the conception, design of study and revision of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
3236305	22047220	SA	2	performed the experiments and drafted the manuscript	performed the experiments and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6163875	29986480	A.C.	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6163875	29986480	G.C.	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6163875	29986480	I.K.	PLoS52	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
6163875	29986480	P.-L.T.	PLoS52	conceived and designed the experiments|revised and approved the final version of the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6163875	29986480	P.-L.T.	PLoS52	conceived and designed the experiments|revised and approved the final version of the manuscript	revised and approved the final version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
6163875	29986480	Z.R.-P.	PLoS52	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5427113	28553298	S. Authors	5	contributed as follows: introduction and conclusion - all authors	contributed as follows: introduction and conclusion - all authors	-	-	NO
4397086	25874611	JS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397086	25874611	JS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397086	25874611	RB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397086	25874611	RB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397086	25874611	RB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397086	25874611	RW	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4397086	25874611	RW	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4397086	25874611	ST	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397086	25874611	ST	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397086	25874611	ST	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397086	25874611	WC	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4397086	25874611	WC	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4397086	25874611	YJ	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4397086	25874611	YJ	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4992315	27543103	DF	2	conceived the experiments and obtained the financial supports	conceived the experiments and obtained the financial supports	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
4992315	27543103	NMH	2	generated the mutants and performed the conjugation experiments|wrote the manuscript that was approved by all authors	generated the mutants and performed the conjugation experiments	Performed the experiments	Investigation	YES
4992315	27543103	NMH	2	generated the mutants and performed the conjugation experiments|wrote the manuscript that was approved by all authors	wrote the manuscript that was approved by all authors	Wrote the paper	Writing - Original Draft	YES
4992315	27543103	YD	2	conceived the experiments and obtained the financial supports|wrote the manuscript that was approved by all authors	conceived the experiments and obtained the financial supports	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
4992315	27543103	YD	2	conceived the experiments and obtained the financial supports|wrote the manuscript that was approved by all authors	wrote the manuscript that was approved by all authors	Wrote the paper	Writing - Original Draft	YES
3236309	21996025	FFB	2	proposed, planned and supervised the whole work	proposed, planned and supervised the whole work	Conceived and designed the experiments	Conceptualization|Supervision	YES
3236309	21996025	HE	2	carried out the experimental work	carried out the experimental work	Performed the experiments	Investigation	YES
3236309	21996025	MIW	2	designed the proposed method and analyzed the data statistically	designed the proposed method and analyzed the data statistically	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
3236309	21996025	NME	2	coordinated the study and modified the text	coordinated the study and modified the text	-	Project administration	YES
4397087	25874696	APB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397087	25874696	APB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397087	25874696	APB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397087	25874696	APB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397087	25874696	CPM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397087	25874696	CPM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397087	25874696	CPM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397087	25874696	CPM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397087	25874696	CS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4397087	25874696	JMH	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397087	25874696	KV	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4397087	25874696	PN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397087	25874696	PN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4397087	25874696	PN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
6164009	29954050	All	2	the authors	the authors	-	-	NO
6164009	29954050	E.C.	2	have contributed to conceptualization, writing and supervisioning it	have contributed to conceptualization, writing and supervisioning it	Conceived and designed the experiments|Wrote the paper	Conceptualization|Supervision	YES
6164009	29954050	F.C.	2	have contributed to conceptualization, writing and supervisioning it	have contributed to conceptualization, writing and supervisioning it	Conceived and designed the experiments|Wrote the paper	Conceptualization|Supervision	YES
6164009	29954050	J.L.P.	2	have contributed to conceptualization, writing and supervisioning it	have contributed to conceptualization, writing and supervisioning it	Conceived and designed the experiments|Wrote the paper	Conceptualization|Supervision	YES
6164009	29954050	L.P.	2	have contributed to conceptualization, writing and supervisioning it	have contributed to conceptualization, writing and supervisioning it	Conceived and designed the experiments|Wrote the paper	Conceptualization|Supervision	YES
6164009	29954050	M.F.	2	have contributed to conceptualization, writing and supervisioning it	have contributed to conceptualization, writing and supervisioning it	Conceived and designed the experiments|Wrote the paper	Conceptualization|Supervision	YES
6164009	29954050	P.R.	2	have contributed to conceptualization, writing and supervisioning it	have contributed to conceptualization, writing and supervisioning it	Conceived and designed the experiments|Wrote the paper	Conceptualization|Supervision	YES
5427120	28553308	FW	2	designed the study, performed experiment, ran data analysis and prepared the draft of manuscript	designed the study, performed experiment, ran data analysis and prepared the draft of manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5427120	28553308	MW	2	performed some of experiments	performed some of experiments	Performed the experiments	Investigation	YES
5427120	28553308	SZ	2	participated in some of experiments and assisted in the preparation of manuscript	participated in some of experiments and assisted in the preparation of manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5427120	28553308	WS	2	participated in some of experiments and assisted in the preparation of manuscript	participated in some of experiments and assisted in the preparation of manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5427120	28553308	XL	2	performed some of experiments	performed some of experiments	Performed the experiments	Investigation	YES
5427120	28553308	XZ	2	is responsible for overall supervision of the study and revised subsequent versions of the manuscript	is responsible for overall supervision of the study and revised subsequent versions of the manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
5427120	28553308	YX	2	performed some of experiments	performed some of experiments	Performed the experiments	Investigation	YES
3238223	21982305	AB	2	conceived and supervised this research work, participated in the data analysis and drafted the manuscript	conceived and supervised this research work, participated in the data analysis and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Supervision|Writing - Original Draft	YES
3238223	21982305	PG	2	carried out the drug analysis and the validation studies	carried out the drug analysis and the validation studies	Performed the experiments	Investigation|Validation	YES
6321443	30388786	A.B.	2	set-up and performed the high-speed imaging experiments	set-up and performed the high-speed imaging experiments	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
6321443	30388786	B.H.v.O.	2	designed and fabricated the applicator	designed and fabricated the applicator	Conceived and designed the experiments|Performed the experiments	Investigation	YES
6321443	30388786	C.O.	2	contributed to the scientific content/discussions during the construction of the manuscript|provided the equipment for high-speed imaging and interpreting this data	contributed to the scientific content/discussions during the construction of the manuscript	Performed the experiments	Investigation	YES
6321443	30388786	C.O.	2	contributed to the scientific content/discussions during the construction of the manuscript|provided the equipment for high-speed imaging and interpreting this data	provided the equipment for high-speed imaging and interpreting this data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources|Visualization	YES
6321443	30388786	G.K.	2	contributed to the scientific content/discussions during the construction of the manuscript|supported in reagents, materials and tools to quantify the penetration efficiency and the delivery of the fluorescently labelled protein into skin	contributed to the scientific content/discussions during the construction of the manuscript	Performed the experiments	Investigation	YES
6321443	30388786	G.K.	2	contributed to the scientific content/discussions during the construction of the manuscript|supported in reagents, materials and tools to quantify the penetration efficiency and the delivery of the fluorescently labelled protein into skin	supported in reagents, materials and tools to quantify the penetration efficiency and the delivery of the fluorescently labelled protein into skin	Performed the experiments	Investigation	YES
6321443	30388786	J.B.	2	contributed to the scientific content/discussions during the construction of the manuscript|supported in reagents, materials and tools to quantify the penetration efficiency and the delivery of the fluorescently labelled protein into skin	contributed to the scientific content/discussions during the construction of the manuscript	Performed the experiments	Investigation	YES
6321443	30388786	J.B.	2	contributed to the scientific content/discussions during the construction of the manuscript|supported in reagents, materials and tools to quantify the penetration efficiency and the delivery of the fluorescently labelled protein into skin	supported in reagents, materials and tools to quantify the penetration efficiency and the delivery of the fluorescently labelled protein into skin	Performed the experiments	Investigation	YES
6321443	30388786	K.v.d.M.	2	conceived, designed and performed the experiments, analysed the data and wrote the paper	conceived, designed and performed the experiments, analysed the data and wrote the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
6321443	30388786	M.L.	2	conceived, designed and performed the experiments, analysed the data and wrote the paper	conceived, designed and performed the experiments, analysed the data and wrote the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
6321443	30388786	M.R.	2	set-up and performed the high-speed imaging experiments	set-up and performed the high-speed imaging experiments	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
6321443	30388786	M.R.N.	2	performed the sem imaging	performed the sem imaging	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
4397088	25875230	CB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397088	25875230	CB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397088	25875230	CB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397088	25875230	CB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397088	25875230	CB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397088	25875230	GS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397088	25875230	GS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397088	25875230	GS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397088	25875230	MO	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397088	25875230	OO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397088	25875230	OO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397088	25875230	OO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397088	25875230	OO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397088	25875230	OO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397088	25875230	PL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397088	25875230	PL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397088	25875230	PL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397088	25875230	PL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397088	25875230	PL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3238293	21982341	FFB	2	proposed, planned and supervised the whole work	proposed, planned and supervised the whole work	Conceived and designed the experiments	Conceptualization|Supervision	YES
3238293	21982341	MIE	2	coordinated the study and modified the text	coordinated the study and modified the text	-	Project administration	YES
3238293	21982341	MIW	2	designed the proposed method and analyzed the data statistically	designed the proposed method and analyzed the data statistically	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
3238293	21982341	SAE	2	carried out the experimental work	carried out the experimental work	Performed the experiments	Investigation	YES
4992570	27544770	All authors	2	critically reviewed and approved the final manuscript	critically reviewed and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4992570	27544770	FX	2	measured phenotype data|drafted the manuscript	measured phenotype data	Performed the experiments	Investigation	YES
4992570	27544770	FX	2	measured phenotype data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4992570	27544770	JB	2	conceived and designed the study|drafted the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4992570	27544770	JB	2	conceived and designed the study|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4992570	27544770	QH	2	performed data analysis	performed data analysis	Analyzed the data	Formal analysis	YES
4992570	27544770	YP	2	conceived and designed the study|drafted the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4992570	27544770	YP	2	conceived and designed the study|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
6321461	30558366	G.B.	CRediT	Supervision|Writing--original draft	Supervision	-	Supervision	YES
6321461	30558366	G.B.	CRediT	Supervision|Writing--original draft	Writing--original draft	Wrote the paper	Writing - Original Draft	YES
6321461	30558366	G.F.P.	CRediT	Writing--review and editing	Writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6321461	30558366	I.G.	CRediT	Writing--review and editing	Writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6321461	30558366	L.F.	CRediT	Conceptualization	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6321461	30558366	M.C.	CRediT	Formal analysis|Writing--original draft	Formal analysis	Analyzed the data	Formal analysis	YES
6321461	30558366	M.C.	CRediT	Formal analysis|Writing--original draft	Writing--original draft	Wrote the paper	Writing - Original Draft	YES
6321461	30558366	M.S.	CRediT	Formal analysis|Methodology	Formal analysis	Analyzed the data	Formal analysis	YES
6321461	30558366	M.S.	CRediT	Formal analysis|Methodology	Methodology	Performed the experiments	Methodology	YES
6321461	30558366	P.B.	CRediT	Supervision|Writing--original draft	Supervision	-	Supervision	YES
6321461	30558366	P.B.	CRediT	Supervision|Writing--original draft	Writing--original draft	Wrote the paper	Writing - Original Draft	YES
6321461	30558366	R.G.	CRediT	Conceptualization|Supervision	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6321461	30558366	R.G.	CRediT	Conceptualization|Supervision	Supervision	-	Supervision	YES
6321461	30558366	S.B.	CRediT	Writing--review and editing	Writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6321461	30558366	S.L.	CRediT	Formal analysis|Methodology	Formal analysis	Analyzed the data	Formal analysis	YES
6321461	30558366	S.L.	CRediT	Formal analysis|Methodology	Methodology	Performed the experiments	Methodology	YES
5427124	28553300	All the authors	2	contributed to the analysis of the results and the writing of the manuscript	contributed to the analysis of the results and the writing of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5427124	28553300	CS	2	contributed to the marker-assisted selection standardization and analysis	contributed to the marker-assisted selection standardization and analysis	-	-	NO
5427124	28553300	ES	2	contributed to replicate some experiments	contributed to replicate some experiments	Performed the experiments	Investigation|Validation	YES
5427124	28553300	GA	2	conducted the experiments	conducted the experiments	Performed the experiments	Investigation	YES
5427124	28553300	GZ	2	contributed to the physiological analysis	contributed to the physiological analysis	-	-	NO
5427124	28553300	MA	2	conducted the experiments	conducted the experiments	Performed the experiments	Investigation	YES
5427124	28553300	RC	2	contributed to the physiological analysis	contributed to the physiological analysis	-	-	NO
5427124	28553300	RS	2	conducted the experiments	conducted the experiments	Performed the experiments	Investigation	YES
3239311	22032335	MIW	2	designed the proposed method	designed the proposed method	Conceived and designed the experiments|Performed the experiments	Conceptualization|Methodology	YES
3239311	22032335	NME	2	coordinated the study and modified the text	coordinated the study and modified the text	-	Project administration	YES
3239311	22032335	SS	2	carried out the experimental work and analyzed the data statistically	carried out the experimental work and analyzed the data statistically	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6164110	30029549	A.K.L.	PLoS52	conceived and designed the experiments|performed the experiments|analyzed and interpreted the data|contributed reagents/materials/analysis tools|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6164110	30029549	A.K.L.	PLoS52	conceived and designed the experiments|performed the experiments|analyzed and interpreted the data|contributed reagents/materials/analysis tools|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
6164110	30029549	A.K.L.	PLoS52	conceived and designed the experiments|performed the experiments|analyzed and interpreted the data|contributed reagents/materials/analysis tools|wrote the paper	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
6164110	30029549	A.K.L.	PLoS52	conceived and designed the experiments|performed the experiments|analyzed and interpreted the data|contributed reagents/materials/analysis tools|wrote the paper	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
6164110	30029549	A.K.L.	PLoS52	conceived and designed the experiments|performed the experiments|analyzed and interpreted the data|contributed reagents/materials/analysis tools|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6164110	30029549	E.S.D.	PLoS52	conceived and designed the experiments|performed the experiments|analyzed and interpreted the data|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6164110	30029549	E.S.D.	PLoS52	conceived and designed the experiments|performed the experiments|analyzed and interpreted the data|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
6164110	30029549	E.S.D.	PLoS52	conceived and designed the experiments|performed the experiments|analyzed and interpreted the data|wrote the paper	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
6164110	30029549	E.S.D.	PLoS52	conceived and designed the experiments|performed the experiments|analyzed and interpreted the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6164110	30029549	J.E.M.	PLoS52	conceived and designed the experiments|recruited the study participants|analyzed and interpreted the data|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6164110	30029549	J.E.M.	PLoS52	conceived and designed the experiments|recruited the study participants|analyzed and interpreted the data|wrote the paper	recruited the study participants	Performed the experiments	Investigation	YES
6164110	30029549	J.E.M.	PLoS52	conceived and designed the experiments|recruited the study participants|analyzed and interpreted the data|wrote the paper	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
6164110	30029549	J.E.M.	PLoS52	conceived and designed the experiments|recruited the study participants|analyzed and interpreted the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6164110	30029549	K.A.A.	PLoS52	conceived and designed the experiments|recruited the study participants|performed the experiments|analyzed and interpreted the data|contributed reagents/materials/analysis tools|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6164110	30029549	K.A.A.	PLoS52	conceived and designed the experiments|recruited the study participants|performed the experiments|analyzed and interpreted the data|contributed reagents/materials/analysis tools|wrote the paper	recruited the study participants	Performed the experiments	Investigation	YES
6164110	30029549	K.A.A.	PLoS52	conceived and designed the experiments|recruited the study participants|performed the experiments|analyzed and interpreted the data|contributed reagents/materials/analysis tools|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
6164110	30029549	K.A.A.	PLoS52	conceived and designed the experiments|recruited the study participants|performed the experiments|analyzed and interpreted the data|contributed reagents/materials/analysis tools|wrote the paper	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
6164110	30029549	K.A.A.	PLoS52	conceived and designed the experiments|recruited the study participants|performed the experiments|analyzed and interpreted the data|contributed reagents/materials/analysis tools|wrote the paper	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
6164110	30029549	K.A.A.	PLoS52	conceived and designed the experiments|recruited the study participants|performed the experiments|analyzed and interpreted the data|contributed reagents/materials/analysis tools|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6164110	30029549	N.K.T.D.D.	PLoS52	conceived and designed the experiments|performed the experiments|analyzed and interpreted the data|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6164110	30029549	N.K.T.D.D.	PLoS52	conceived and designed the experiments|performed the experiments|analyzed and interpreted the data|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
6164110	30029549	N.K.T.D.D.	PLoS52	conceived and designed the experiments|performed the experiments|analyzed and interpreted the data|wrote the paper	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
6164110	30029549	N.K.T.D.D.	PLoS52	conceived and designed the experiments|performed the experiments|analyzed and interpreted the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397089	25874712	JLB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397089	25874712	JLB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397089	25874712	JLB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397089	25874712	JLB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397089	25874712	LAFBL	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4397089	25874712	LAFBL	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4397089	25874712	NMF	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397089	25874712	NOMP	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397089	25874712	NOMP	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4397089	25874712	OGC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397089	25874712	OGC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4397089	25874712	OGC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4397089	25874712	RVS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397089	25874712	RVS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397089	25874712	RVS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397089	25874712	RVS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6321466	30487449	D.-J.J.	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6321466	30487449	H.-J.M.	PLoS52	conceived and designed the experiments|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6321466	30487449	H.-J.M.	PLoS52	conceived and designed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6321466	30487449	J.-H.Y.	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
6321466	30487449	K.A.M.	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6321466	30487449	K.H.C.	PLoS52	conceived and designed the experiments|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6321466	30487449	K.H.C.	PLoS52	conceived and designed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6321466	30487449	R.M.K.	PLoS52	performed the experiments|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
6321466	30487449	R.M.K.	PLoS52	performed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6321466	30487449	Y.C.K.	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5427127	28553302	All authors	2	contributed equally to the writing of this manuscript	contributed equally to the writing of this manuscript	Wrote the paper	Writing - Original Draft	YES
5427127	28553302	BT	2	supervised the project and assisted with analysis of all data	supervised the project and assisted with analysis of all data	Analyzed the data	Formal analysis|Supervision	YES
5427127	28553302	FW	2	supervised the project and assisted with analysis of all data	supervised the project and assisted with analysis of all data	Analyzed the data	Formal analysis|Supervision	YES
5427127	28553302	GC	2	supervised the bioinformatics analysis	supervised the bioinformatics analysis	-	Formal analysis|Supervision	YES
5427127	28553302	GS	2	supervised the bioinformatics analysis	supervised the bioinformatics analysis	-	Formal analysis|Supervision	YES
5427127	28553302	JB	2	carried out all of the rna seq data analysis, conduct chromosomal distribution experiment, and analysis of chromosomal spread results	carried out all of the rna seq data analysis, conduct chromosomal distribution experiment, and analysis of chromosomal spread results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5427127	28553302	XW	2	supervised the project and assisted with analysis of all data	supervised the project and assisted with analysis of all data	Analyzed the data	Formal analysis|Supervision	YES
5427127	28553302	YY	2	carried out all of the rna seq data analysis, conduct chromosomal distribution experiment, and analysis of chromosomal spread results	carried out all of the rna seq data analysis, conduct chromosomal distribution experiment, and analysis of chromosomal spread results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5427127	28553302	ZW	2	assist with rna preparation for rna seq	assist with rna preparation for rna seq	Performed the experiments	Investigation	YES
4779111	26821801	CH	2	contributed to data interpretation and manuscript writing	contributed to data interpretation and manuscript writing	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4779111	26821801	JPGP	2	contributed to data collection, data analysis, data interpretation, and proof reading of the manuscript	contributed to data collection, data analysis, data interpretation, and proof reading of the manuscript	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4779111	26821801	KJ	2	contributed to data collection, data analysis, data interpretation, and proof reading of the manuscript	contributed to data collection, data analysis, data interpretation, and proof reading of the manuscript	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4779111	26821801	MJS	2	contributed to data collection, data analysis, data interpretation, and proof reading of the manuscript	contributed to data collection, data analysis, data interpretation, and proof reading of the manuscript	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4779111	26821801	MJW	2	performed experimental design, data interpretation, and contributed to manuscript writing	performed experimental design, data interpretation, and contributed to manuscript writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4779111	26821801	MR	2	contributed to data collection, data analysis, data interpretation, and proof reading of the manuscript	contributed to data collection, data analysis, data interpretation, and proof reading of the manuscript	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4779111	26821801	NS	2	contributed to data collection, data analysis, data interpretation, and proof reading of the manuscript	contributed to data collection, data analysis, data interpretation, and proof reading of the manuscript	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4779111	26821801	RM	2	performed experimental design, data interpretation, and contributed to manuscript writing	performed experimental design, data interpretation, and contributed to manuscript writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4779111	26821801	RW	2	contributed to data collection, data analysis, data interpretation, and proof reading of the manuscript	contributed to data collection, data analysis, data interpretation, and proof reading of the manuscript	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4779111	26821801	TKvdM	2	contributed to data collection, data analysis, data interpretation, and proof reading of the manuscript	contributed to data collection, data analysis, data interpretation, and proof reading of the manuscript	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4779111	26821801	TTGN	2	contributed to the experimental design, data collection, and data analysis and performed manuscript writing	contributed to the experimental design, data collection, and data analysis and performed manuscript writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
4397090	25875169	ALR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397090	25875169	ALR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397090	25875169	ALR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397090	25875169	ALR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397090	25875169	ALR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397090	25875169	GL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397090	25875169	GL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397090	25875169	GL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397090	25875169	GL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397090	25875169	GL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397090	25875169	SEB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397090	25875169	SEB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397090	25875169	SEB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397090	25875169	SEB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397090	25875169	SEB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3247183	22035035	SAE	2	contributed to data analyses and to finalizing the manuscript	contributed to data analyses and to finalizing the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
3247183	22035035	SGA	2	contributed to data analyses and to finalizing the manuscript	contributed to data analyses and to finalizing the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4994203	27550217	A-MC	2	conducted experiments	conducted experiments	Performed the experiments	Investigation	YES
4994203	27550217	AH	2	designed experiments	designed experiments	Conceived and designed the experiments	Methodology	YES
4994203	27550217	AN	2	conducted experiments	conducted experiments	Performed the experiments	Investigation	YES
4994203	27550217	CA	2	designed experiments|conducted experiments|wrote scripts for computational analysis	designed experiments	Conceived and designed the experiments	Methodology	YES
4994203	27550217	CA	2	designed experiments|conducted experiments|wrote scripts for computational analysis	conducted experiments	Performed the experiments	Investigation	YES
4994203	27550217	CA	2	designed experiments|conducted experiments|wrote scripts for computational analysis	wrote scripts for computational analysis	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Software|Writing - Original Draft	YES
4994203	27550217	CJ	2	wrote scripts for computational analysis	wrote scripts for computational analysis	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Software|Writing - Original Draft	YES
4994203	27550217	DJ	2	designed experiments	designed experiments	Conceived and designed the experiments	Methodology	YES
4994203	27550217	GL	2	designed experiments|conducted experiments	designed experiments	Conceived and designed the experiments	Methodology	YES
4994203	27550217	GL	2	designed experiments|conducted experiments	conducted experiments	Performed the experiments	Investigation	YES
4994203	27550217	J. All	2	authors edited and approved the manuscript	authors edited and approved the manuscript	Wrote the paper	Writing - Review & Editing	YES
4994203	27550217	JE	2	designed experiments	designed experiments	Conceived and designed the experiments	Methodology	YES
4994203	27550217	MAK	2	conducted experiments	conducted experiments	Performed the experiments	Investigation	YES
4994203	27550217	NU	2	conducted experiments	conducted experiments	Performed the experiments	Investigation	YES
4994203	27550217	PD	2	designed experiments	designed experiments	Conceived and designed the experiments	Methodology	YES
6321467	30513791	A.F.	2	conceived the study|designed and performed the experiments, acquired, analyzed, and interpreted the data	conceived the study	Conceived and designed the experiments	Conceptualization	YES
6321467	30513791	A.F.	2	conceived the study|designed and performed the experiments, acquired, analyzed, and interpreted the data	designed and performed the experiments, acquired, analyzed, and interpreted the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
6321467	30513791	All authors	2	have given approval to the final version of the manuscript	have given approval to the final version of the manuscript	-	-	NO
6321467	30513791	S.M.	2	conceived the study|participated in the interpretation of the results	conceived the study	Conceived and designed the experiments	Conceptualization	YES
6321467	30513791	S.M.	2	conceived the study|participated in the interpretation of the results	participated in the interpretation of the results	Analyzed the data	Formal analysis	YES
6321467	30513791	S.V.	2	contributed to revise the manuscript	contributed to revise the manuscript	Wrote the paper	Writing - Review & Editing	YES
6321467	30513791	U.R.C.	2	contributed to revise the manuscript	contributed to revise the manuscript	Wrote the paper	Writing - Review & Editing	YES
3248850	22145711	AA	7	Contributed and participated in the design of the study. He carried out the synthesis of the methyl 9, 10-dihydroxyoctadecanoate and drafted the manuscript	Contributed and participated in the design of the study. He carried out the synthesis of the methyl 9, 10-dihydroxyoctadecanoate and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
3248850	22145711	BR	7	Contributed and participated in the design of the study and co-supervised it	Contributed and participated in the design of the study and co-supervised it	Conceived and designed the experiments	Methodology|Supervision	YES
3248850	22145711	MN	7	Participated in the gc and gc-ms analysis	Participated in the gc and gc-ms analysis	-	-	NO
3248850	22145711	RO	7	Contributed in the design of the study	Contributed in the design of the study	Conceived and designed the experiments	Methodology	YES
3248850	22145711	RP	7	Contributed in the design of the study and coordination. He also provided a laboratory space for the research work	Contributed in the design of the study and coordination. He also provided a laboratory space for the research work	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Project administration	YES
6164221	30200654	A.L.	CRediT	writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6164221	30200654	A.O.	CRediT	writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6164221	30200654	F.A.	CRediT	Conceptualization|writing--original draft preparation|writing--review and editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6164221	30200654	F.A.	CRediT	Conceptualization|writing--original draft preparation|writing--review and editing	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6164221	30200654	F.A.	CRediT	Conceptualization|writing--original draft preparation|writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
4994206	27552804	AV	PLoS52	conceived and designed the study|performed genome analysis|analyzed the data|wrote the paper	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4994206	27552804	AV	PLoS52	conceived and designed the study|performed genome analysis|analyzed the data|wrote the paper	performed genome analysis	Performed the experiments	Investigation	YES
4994206	27552804	AV	PLoS52	conceived and designed the study|performed genome analysis|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
4994206	27552804	AV	PLoS52	conceived and designed the study|performed genome analysis|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4994206	27552804	CW	PLoS52	conceived and designed the study|analyzed the data|wrote the paper	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4994206	27552804	CW	PLoS52	conceived and designed the study|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
4994206	27552804	CW	PLoS52	conceived and designed the study|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4994206	27552804	ES	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4994206	27552804	GH	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4994206	27552804	HvdG	PLoS52	performed assembly|wrote the paper	performed assembly	Performed the experiments	Investigation	YES
4994206	27552804	HvdG	PLoS52	performed assembly|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4994206	27552804	KA	PLoS52	conceived and designed the study|wrote the paper	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4994206	27552804	KA	PLoS52	conceived and designed the study|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4994206	27552804	MH	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4994206	27552804	SDS	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4994206	27552804	SW	PLoS52	performed annotation|analyzed the data|wrote the paper	performed annotation	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
4994206	27552804	SW	PLoS52	performed annotation|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
4994206	27552804	SW	PLoS52	performed annotation|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4994206	27552804	TvdL	PLoS52	conceived and designed the study|analyzed the data|wrote the paper	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4994206	27552804	TvdL	PLoS52	conceived and designed the study|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
4994206	27552804	TvdL	PLoS52	conceived and designed the study|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3253695	22067202	VSP	5	contributed for synthesis and spectral analysis under the guidance NS|contributed bioconjugation study and photophysical study under the guidance NS|contributed bioconjugation study and photophysical study under the guidance NS	contributed for synthesis and spectral analysis under the guidance NS	-	Supervision	YES
3253695	22067202	VSP	5	contributed for synthesis and spectral analysis under the guidance NS|contributed bioconjugation study and photophysical study under the guidance NS|contributed bioconjugation study and photophysical study under the guidance NS	contributed bioconjugation study and photophysical study under the guidance NS	-	Supervision	YES
3253695	22067202	VSP	5	contributed for synthesis and spectral analysis under the guidance NS|contributed bioconjugation study and photophysical study under the guidance NS|contributed bioconjugation study and photophysical study under the guidance NS	contributed bioconjugation study and photophysical study under the guidance NS	-	Supervision	YES
4397091	25874956	AC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397091	25874956	DP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397091	25874956	DP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397091	25874956	DP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397091	25874956	DP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397091	25874956	GJS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397091	25874956	PJR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397091	25874956	PJR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397091	25874956	PJR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397091	25874956	PJR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397091	25874956	RS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397091	25874956	S. Sinha	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4397091	25874956	S. Sinha	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4397091	25874956	S. Srivastava	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397091	25874956	S. Srivastava	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397091	25874956	S. Srivastava	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397091	25874956	S. Srivastava	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397091	25874956	SD	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397091	25874956	SR	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397091	25874956	SR	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397091	25874956	TSKP	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5427129	28553296	AF	2	designed the perspective and all the authors wrote the manuscript	designed the perspective and all the authors wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
5427129	28553296	AG	2	designed the perspective and all the authors wrote the manuscript	designed the perspective and all the authors wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
5427129	28553296	QG	2	designed the perspective and all the authors wrote the manuscript	designed the perspective and all the authors wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
6321471	30445705	A.J.N.	2	conceptualized the project, suggested methodology and reviewed the manuscript	conceptualized the project, suggested methodology and reviewed the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
6321471	30445705	G.C.	2	supervised the project, conceptualized it and reviewed the original manuscript	supervised the project, conceptualized it and reviewed the original manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Supervision|Writing - Review & Editing	YES
6321471	30445705	L.I.	2	performed experiments and wrote the original manuscript	performed experiments and wrote the original manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6321471	30445705	M.A.	2	performed experiments, suggested methodology and wrote the original draft	performed experiments, suggested methodology and wrote the original draft	Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
6321471	30445705	O.M.M.	2	conceptualized the project, suggested methodology, provided resources and funding, and edited the manuscript	conceptualized the project, suggested methodology, provided resources and funding, and edited the manuscript	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Funding acquisition|Methodology|Resources|Writing - Review & Editing	YES
6321471	30445705	S.D.	2	conceptualized the project, suggested methodology and reviewed the manuscript	conceptualized the project, suggested methodology and reviewed the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
4994242	27549615	BWD	2	provided unrelated golden retrievers for comparison analyses and feedback on the methods and manuscript	provided unrelated golden retrievers for comparison analyses and feedback on the methods and manuscript	Performed the experiments|Analyzed the data	Formal analysis	YES
4994242	27549615	CB-A	2	performed qrt-pcr experiments	performed qrt-pcr experiments	Performed the experiments	Investigation	YES
4994242	27549615	CB-L	2	carried out the association studies, evaluated snp effects, performed haplotyping and linear regression analyses as well as all statistics, and drafted the manuscript	carried out the association studies, evaluated snp effects, performed haplotyping and linear regression analyses as well as all statistics, and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4994242	27549615	JC	2	provided assistance with all association studies and feedback while drafting the manuscript	provided assistance with all association studies and feedback while drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
4994242	27549615	JNK	2	provided grmd colony samples and phenotype data	provided grmd colony samples and phenotype data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
3260099	22185578	GZ	2	performed the experiments and drafted the manuscript	performed the experiments and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3260099	22185578	HL	2	synthesized the standards of oh-pcb3 and revised the manuscript	synthesized the standards of oh-pcb3 and revised the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
3260099	22185578	JS	2	participated in the conception, design of study and revision of the manuscript	participated in the conception, design of study and revision of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
6164475	30110885	J.B.C.	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6164475	30110885	J.C.G.	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6164475	30110885	S.A.	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5427144	28553303	AP	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5427144	28553303	EB	2	conducted the experiments	conducted the experiments	Performed the experiments	Investigation	YES
5427144	28553303	EL	2	interpreted and prepared the manuscript	interpreted and prepared the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5427144	28553303	GG	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5427144	28553303	MO	2	designed the experiments|conducted the experiments|interpreted and prepared the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5427144	28553303	MO	2	designed the experiments|conducted the experiments|interpreted and prepared the manuscript	conducted the experiments	Performed the experiments	Investigation	YES
5427144	28553303	MO	2	designed the experiments|conducted the experiments|interpreted and prepared the manuscript	interpreted and prepared the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5427144	28553303	MO-S	2	designed the experiments|interpreted and prepared the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5427144	28553303	MO-S	2	designed the experiments|interpreted and prepared the manuscript	interpreted and prepared the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5427144	28553303	RO	2	conducted the experiments	conducted the experiments	Performed the experiments	Investigation	YES
6321472	30424501	B.D.	CRediT	Methodology|Formal analysis|investigation|Resources|Writing--original draft preparation	Methodology	Performed the experiments	Methodology	YES
6321472	30424501	B.D.	CRediT	Methodology|Formal analysis|investigation|Resources|Writing--original draft preparation	Formal analysis	Analyzed the data	Formal analysis	YES
6321472	30424501	B.D.	CRediT	Methodology|Formal analysis|investigation|Resources|Writing--original draft preparation	investigation	Performed the experiments	Investigation	YES
6321472	30424501	B.D.	CRediT	Methodology|Formal analysis|investigation|Resources|Writing--original draft preparation	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6321472	30424501	B.D.	CRediT	Methodology|Formal analysis|investigation|Resources|Writing--original draft preparation	Writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6321472	30424501	H.M.A.	CRediT	Methodology|Resources|Writing--review and editing	Methodology	Performed the experiments	Methodology	YES
6321472	30424501	H.M.A.	CRediT	Methodology|Resources|Writing--review and editing	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6321472	30424501	H.M.A.	CRediT	Methodology|Resources|Writing--review and editing	Writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6321472	30424501	S.M.B.	CRediT	Conceptualization|Methodology|Writing--review and editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6321472	30424501	S.M.B.	CRediT	Conceptualization|Methodology|Writing--review and editing	Methodology	Performed the experiments	Methodology	YES
6321472	30424501	S.M.B.	CRediT	Conceptualization|Methodology|Writing--review and editing	Writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
5204062	28077975	All the authors	2	contributed to the study concept and design|have read and approved every part of the work|accept the responsibility of the content of the paper	contributed to the study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5204062	28077975	All the authors	2	contributed to the study concept and design|have read and approved every part of the work|accept the responsibility of the content of the paper	have read and approved every part of the work	-	-	NO
5204062	28077975	All the authors	2	contributed to the study concept and design|have read and approved every part of the work|accept the responsibility of the content of the paper	accept the responsibility of the content of the paper	-	-	NO
4397092	25875597	CS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4397092	25875597	CS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397092	25875597	DV	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397092	25875597	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397092	25875597	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397092	25875597	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397092	25875597	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397092	25875597	JMA	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397092	25875597	JMA	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397092	25875597	JMA	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397092	25875597	LJ	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4397092	25875597	LJ	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397092	25875597	MG	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397092	25875597	MG	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397092	25875597	SB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4397092	25875597	VG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
3262757	22152108	AJCB	2	carried out growth experiments	carried out growth experiments	Performed the experiments	Investigation	YES
3262757	22152108	CSW	2	helped with inhibitor synthesis	helped with inhibitor synthesis	-	-	NO
3262757	22152108	DK	2	conceived the study, participated in its design and coordination and helped to draft the manuscript	conceived the study, participated in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
3262757	22152108	MCB	2	participated in study design, helped synthesise the jnk inhibitors, and helped to draft the manuscript	participated in study design, helped synthesise the jnk inhibitors, and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3262757	22152108	MCD	2	synthesised the inhibitors	synthesised the inhibitors	-	-	NO
3262757	22152108	MJR	2	carried out the immunoassays and elisa assays	carried out the immunoassays and elisa assays	Performed the experiments	Investigation	YES
3262757	22152108	TD	2	participated in study design and coordination, manuscript preparation, and carried out growth experiments	participated in study design and coordination, manuscript preparation, and carried out growth experiments	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Project administration|Writing - Original Draft	YES
6321473	30326564	I.-h.B.	PLoS52	conceived and designed the experiments|analyzed the data and wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6321473	30326564	I.-h.B.	PLoS52	conceived and designed the experiments|analyzed the data and wrote the paper	analyzed the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6321473	30326564	J.-S.K.	PLoS52	performed the experiments|analyzed the data and wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
6321473	30326564	J.-S.K.	PLoS52	performed the experiments|analyzed the data and wrote the paper	analyzed the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6321473	30326564	M.-S.K.	PLoS52	conceived and designed the experiments|analyzed the data and wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6321473	30326564	M.-S.K.	PLoS52	conceived and designed the experiments|analyzed the data and wrote the paper	analyzed the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6164477	29973489	A.C.	CRediT	Conceptualization	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6164477	29973489	G.F.	CRediT	Validation|Data curation	Validation	Performed the experiments	Validation	YES
6164477	29973489	G.F.	CRediT	Validation|Data curation	Data curation	Analyzed the data	Data curation	YES
6164477	29973489	G.G.	CRediT	Validation|Writing--review & editing	Validation	Performed the experiments	Validation	YES
6164477	29973489	G.G.	CRediT	Validation|Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6164477	29973489	G.M.	CRediT	Formal analysis|Visualization|Supervision	Formal analysis	Analyzed the data	Formal analysis	YES
6164477	29973489	G.M.	CRediT	Formal analysis|Visualization|Supervision	Visualization	Analyzed the data	Visualization	YES
6164477	29973489	G.M.	CRediT	Formal analysis|Visualization|Supervision	Supervision	-	Supervision	YES
6164477	29973489	L.B.	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
6164477	29973489	M.F.	CRediT	Formal analysis	Formal analysis	Analyzed the data	Formal analysis	YES
6164477	29973489	P.S.	CRediT	Conceptualization|Methodology|Resources|Writing--original draft preparation	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6164477	29973489	P.S.	CRediT	Conceptualization|Methodology|Resources|Writing--original draft preparation	Methodology	Performed the experiments	Methodology	YES
6164477	29973489	P.S.	CRediT	Conceptualization|Methodology|Resources|Writing--original draft preparation	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6164477	29973489	P.S.	CRediT	Conceptualization|Methodology|Resources|Writing--original draft preparation	Writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6164477	29973489	S.M.	CRediT	Validation	Validation	Performed the experiments	Validation	YES
6164477	29973489	W.D.I.	CRediT	Conceptualization	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
4391522	25883981	Duo Mao	2	contributed equally to this work	contributed equally to this work	-	-	NO
4391522	25883981	Xinpeng Yao	2	contributed equally to this work	contributed equally to this work	-	-	NO
4994258	27552843	AA	2	post-doctoral position employed on this project, did all microarrays experiments and interpretations|carried out the molecular genetic studies, participated in the sequence alignment and drafted the manuscript	post-doctoral position employed on this project, did all microarrays experiments and interpretations	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4994258	27552843	AA	2	post-doctoral position employed on this project, did all microarrays experiments and interpretations|carried out the molecular genetic studies, participated in the sequence alignment and drafted the manuscript	carried out the molecular genetic studies, participated in the sequence alignment and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4994258	27552843	AB	2	to prepare all the rna extraction and microarrays experiments	to prepare all the rna extraction and microarrays experiments	Performed the experiments	Investigation	YES
4994258	27552843	AL	2	did the chemical analyses, enzyme activity assays and characterization of wheat straw degradation by consortium	did the chemical analyses, enzyme activity assays and characterization of wheat straw degradation by consortium	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4994258	27552843	CD	2	are the project coordinators, conceived the study, and participated in its design and coordination and helped to draft the manuscript	are the project coordinators, conceived the study, and participated in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
4994258	27552843	GA	2	did all the gene cloning and prepared the termite and rumen libraries	did all the gene cloning and prepared the termite and rumen libraries	Performed the experiments	Investigation	YES
4994258	27552843	GHR	2	revised the manuscript critically for important intellectual content	revised the manuscript critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4994258	27552843	LA	2	did the chemical analyses, enzyme activity assays and characterization of wheat straw degradation by consortium	did the chemical analyses, enzyme activity assays and characterization of wheat straw degradation by consortium	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4994258	27552843	MOD	2	revised the manuscript critically for important intellectual content	revised the manuscript critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4994258	27552843	VAL	2	are the project coordinators, conceived the study, and participated in its design and coordination and helped to draft the manuscript	are the project coordinators, conceived the study, and participated in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
3264508	22222098	CF	2	performed the research including data collection, test and analysis	performed the research including data collection, test and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3264508	22222098	FLL	2	performed the research including data collection, test and analysis	performed the research including data collection, test and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3264508	22222098	HYW	2	performed the research including data collection, test and analysis	performed the research including data collection, test and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3264508	22222098	JK	2	suggested extension and modifications to the research	suggested extension and modifications to the research	-	-	NO
3264508	22222098	LGS	2	carefully proofread the manuscript	carefully proofread the manuscript	-	-	NO
3264508	22222098	YLB	2	suggested extension and modifications to the research	suggested extension and modifications to the research	-	-	NO
3264508	22222098	YXH	2	conceived and designed the research	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
3264508	22222098	YXL	2	supervised the whole research and revised the manuscript critically	supervised the whole research and revised the manuscript critically	Wrote the paper	Supervision|Writing - Review & Editing	YES
3264508	22222098	YXS	2	conceived and designed the research|performed the research including data collection, test and analysis	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
3264508	22222098	YXS	2	conceived and designed the research|performed the research including data collection, test and analysis	performed the research including data collection, test and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3264508	22222098	ZQM	2	carefully proofread the manuscript	carefully proofread the manuscript	-	-	NO
5427154	28553307	DH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5427154	28553307	FM	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5427154	28553307	FZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5427154	28553307	JW	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5427154	28553307	LD	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5427154	28553307	LJ	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5427154	28553307	PX	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5427154	28553307	PX	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5427154	28553307	QC	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5427154	28553307	RL	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5427154	28553307	SF	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5427154	28553307	SZ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5427154	28553307	SZ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5427154	28553307	WL	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
6321492	30373187	A.D.	CRediT	Resources|Writing--original draft preparation|Writing--review & editing	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6321492	30373187	A.D.	CRediT	Resources|Writing--original draft preparation|Writing--review & editing	Writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6321492	30373187	A.D.	CRediT	Resources|Writing--original draft preparation|Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6321492	30373187	E.G.	CRediT	Conceptualization|Project administration|Writing--review & editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6321492	30373187	E.G.	CRediT	Conceptualization|Project administration|Writing--review & editing	Project administration	-	Project administration	YES
6321492	30373187	E.G.	CRediT	Conceptualization|Project administration|Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6321492	30373187	G.R.	CRediT	Investigation|Writing--original draft preparation|Writing--review & editing	Investigation	Performed the experiments	Investigation	YES
6321492	30373187	G.R.	CRediT	Investigation|Writing--original draft preparation|Writing--review & editing	Writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6321492	30373187	G.R.	CRediT	Investigation|Writing--original draft preparation|Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6321492	30373187	L.F.	CRediT	Resources|Writing--original draft preparation	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6321492	30373187	L.F.	CRediT	Resources|Writing--original draft preparation	Writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6321492	30373187	P.G.	CRediT	Conceptualization|Resources	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6321492	30373187	P.G.	CRediT	Conceptualization|Resources	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6164700	29966270	K.H.	2	searched the bibliography and made critical revisions	searched the bibliography and made critical revisions	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
6164700	29966270	N.Y.	2	conceived and wrote the manuscript	conceived and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
6164700	29966270	T.Y.	2	conceived and wrote the manuscript and made critical revisions	conceived and wrote the manuscript and made critical revisions	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
3268747	22152033	AJWS	2	conceived the experiments	conceived the experiments	Conceived and designed the experiments	Conceptualization	YES
3268747	22152033	ALJ	2	conceived the experiments|performed crystallographic studies	conceived the experiments	Conceived and designed the experiments	Conceptualization	YES
3268747	22152033	ALJ	2	conceived the experiments|performed crystallographic studies	performed crystallographic studies	Performed the experiments	Investigation	YES
3268747	22152033	DvdW	2	synthesised all reported compounds	synthesised all reported compounds	Performed the experiments	Investigation	YES
3268747	22152033	MAK	2	synthesised all reported compounds	synthesised all reported compounds	Performed the experiments	Investigation	YES
3268747	22152033	SEL	2	conceived the experiments|wrote the manuscript	conceived the experiments	Conceived and designed the experiments	Conceptualization	YES
3268747	22152033	SEL	2	conceived the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3268747	22152033	TP	2	synthesised all reported compounds	synthesised all reported compounds	Performed the experiments	Investigation	YES
4397094	25874457	HU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Analyzed results|Manuscript preparation	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397094	25874457	HU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Analyzed results|Manuscript preparation	Performed the experiments	Performed the experiments	Investigation	YES
4397094	25874457	HU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Analyzed results|Manuscript preparation	Analyzed the data	Analyzed the data	Formal analysis	YES
4397094	25874457	HU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Analyzed results|Manuscript preparation	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397094	25874457	HU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Analyzed results|Manuscript preparation	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397094	25874457	HU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Analyzed results|Manuscript preparation	Analyzed results	Analyzed the data	Formal analysis	YES
4397094	25874457	HU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Analyzed results|Manuscript preparation	Manuscript preparation	Wrote the paper	Writing - Original Draft	YES
4397094	25874457	IK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Analyzed results|Manuscript preparation	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397094	25874457	IK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Analyzed results|Manuscript preparation	Performed the experiments	Performed the experiments	Investigation	YES
4397094	25874457	IK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Analyzed results|Manuscript preparation	Analyzed the data	Analyzed the data	Formal analysis	YES
4397094	25874457	IK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Analyzed results|Manuscript preparation	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397094	25874457	IK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Analyzed results|Manuscript preparation	Analyzed results	Analyzed the data	Formal analysis	YES
4397094	25874457	IK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Analyzed results|Manuscript preparation	Manuscript preparation	Wrote the paper	Writing - Original Draft	YES
4397094	25874457	MF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Analyzed results|Manuscript preparation	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397094	25874457	MF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Analyzed results|Manuscript preparation	Analyzed the data	Analyzed the data	Formal analysis	YES
4397094	25874457	MF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Analyzed results|Manuscript preparation	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397094	25874457	MF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Analyzed results|Manuscript preparation	Analyzed results	Analyzed the data	Formal analysis	YES
4397094	25874457	MF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Analyzed results|Manuscript preparation	Manuscript preparation	Wrote the paper	Writing - Original Draft	YES
4397094	25874457	SI	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Analyzed results|Manuscript preparation	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397094	25874457	SI	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Analyzed results|Manuscript preparation	Performed the experiments	Performed the experiments	Investigation	YES
4397094	25874457	SI	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Analyzed results|Manuscript preparation	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397094	25874457	SI	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Analyzed results|Manuscript preparation	Analyzed results	Analyzed the data	Formal analysis	YES
4397094	25874457	SI	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Analyzed results|Manuscript preparation	Manuscript preparation	Wrote the paper	Writing - Original Draft	YES
4397094	25874457	SS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Analyzed results|Manuscript preparation	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397094	25874457	SS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Analyzed results|Manuscript preparation	Analyzed the data	Analyzed the data	Formal analysis	YES
4397094	25874457	SS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Analyzed results|Manuscript preparation	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397094	25874457	SS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Analyzed results|Manuscript preparation	Analyzed results	Analyzed the data	Formal analysis	YES
4397094	25874457	SS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Analyzed results|Manuscript preparation	Manuscript preparation	Wrote the paper	Writing - Original Draft	YES
5427459	28553305	B-GK	2	wrote the manuscript, analyzed data and designed experiments	wrote the manuscript, analyzed data and designed experiments	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5427459	28553305	HK	2	wrote the manuscript, analyzed data and designed experiments	wrote the manuscript, analyzed data and designed experiments	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5427459	28553305	S-JM	2	wrote the manuscript, analyzed data and designed experiments	wrote the manuscript, analyzed data and designed experiments	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5427459	28553305	YL	2	measured the stomata conductance	measured the stomata conductance	Performed the experiments	Investigation	YES
4994294	27549794	LoSVP	2	and lovrn1, arabidopsis transformation and transgenic plants analysis and drafted the manuscript and revised it critically for important intellectual content	and lovrn1, arabidopsis transformation and transgenic plants analysis and drafted the manuscript and revised it critically for important intellectual content	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
4994294	27549794	WL	2	carried out transcriptome sequencing and interpreted data together|contributed equally to this study and should be regarded as co-first authors	carried out transcriptome sequencing and interpreted data together	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4994294	27549794	WL	2	carried out transcriptome sequencing and interpreted data together|contributed equally to this study and should be regarded as co-first authors	contributed equally to this study and should be regarded as co-first authors	-	-	NO
4994294	27549794	XL	2	have made substantial contributions to conception and design, carried out the study of identification and bioinformatics annotation of different genes, and participated in drafting the manuscript|carried out transcriptome sequencing and interpreted data together|contributed equally to this study and should be regarded as co-first authors	have made substantial contributions to conception and design, carried out the study of identification and bioinformatics annotation of different genes, and participated in drafting the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Data curation|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4994294	27549794	XL	2	have made substantial contributions to conception and design, carried out the study of identification and bioinformatics annotation of different genes, and participated in drafting the manuscript|carried out transcriptome sequencing and interpreted data together|contributed equally to this study and should be regarded as co-first authors	carried out transcriptome sequencing and interpreted data together	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4994294	27549794	XL	2	have made substantial contributions to conception and design, carried out the study of identification and bioinformatics annotation of different genes, and participated in drafting the manuscript|carried out transcriptome sequencing and interpreted data together|contributed equally to this study and should be regarded as co-first authors	contributed equally to this study and should be regarded as co-first authors	-	-	NO
4994294	27549794	YL	2	conceived of the study, participated in its design and coordination and have given final approval of the version to be published	conceived of the study, participated in its design and coordination and have given final approval of the version to be published	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
6164850	29970866	Each author	2	contributed equally to the substance of this article and takes responsibility for the content	contributed equally to the substance of this article and takes responsibility for the content	-	-	NO
6394649	30815754	M.C.K.	PLoS52	wrote the manuscript|designed the research|analyzed the data	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6394649	30815754	M.C.K.	PLoS52	wrote the manuscript|designed the research|analyzed the data	designed the research	Conceived and designed the experiments	Methodology	YES
6394649	30815754	M.C.K.	PLoS52	wrote the manuscript|designed the research|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
6394649	30815754	M.M.A.I.	PLoS52	wrote the manuscript|designed the research|performed the research|analyzed the data	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6394649	30815754	M.M.A.I.	PLoS52	wrote the manuscript|designed the research|performed the research|analyzed the data	designed the research	Conceived and designed the experiments	Methodology	YES
6394649	30815754	M.M.A.I.	PLoS52	wrote the manuscript|designed the research|performed the research|analyzed the data	performed the research	Performed the experiments	Investigation	YES
6394649	30815754	M.M.A.I.	PLoS52	wrote the manuscript|designed the research|performed the research|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
6394649	30815754	M.O.K.	PLoS52	wrote the manuscript|designed the research|analyzed the data	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6394649	30815754	M.O.K.	PLoS52	wrote the manuscript|designed the research|analyzed the data	designed the research	Conceived and designed the experiments	Methodology	YES
6394649	30815754	M.O.K.	PLoS52	wrote the manuscript|designed the research|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
6394649	30815754	S.F.	PLoS52	wrote the manuscript|designed the research|analyzed the data	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6394649	30815754	S.F.	PLoS52	wrote the manuscript|designed the research|analyzed the data	designed the research	Conceived and designed the experiments	Methodology	YES
6394649	30815754	S.F.	PLoS52	wrote the manuscript|designed the research|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
6394649	30815754	S.U.	PLoS52	wrote the manuscript|designed the research|analyzed the data	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6394649	30815754	S.U.	PLoS52	wrote the manuscript|designed the research|analyzed the data	designed the research	Conceived and designed the experiments	Methodology	YES
6394649	30815754	S.U.	PLoS52	wrote the manuscript|designed the research|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
3268752	22112283	MW	2	carried out most experiments and drafted the manuscript	carried out most experiments and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3268752	22112283	QZ	2	carried out the measurement of acid base titration	carried out the measurement of acid base titration	Performed the experiments	Investigation	YES
3268752	22112283	WH	2	assisted to the equilibrium calculations	assisted to the equilibrium calculations	Analyzed the data	Formal analysis	YES
3268752	22112283	ZS	2	has formulated the research idea and finalized the manuscript	has formulated the research idea and finalized the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
6321496	30360519	B.L.T.	2	contributed to the study design, conducted the lab work, data acquisition, data analysis and interpretation, and wrote the manuscript	contributed to the study design, conducted the lab work, data acquisition, data analysis and interpretation, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
6321496	30360519	L.C.C.	2	participated in flow cytometry analysis and data interpretation	participated in flow cytometry analysis and data interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6321496	30360519	M.E.N.	2	participated in the study design, data acquisition, advised lab work, and commented final version of the manuscript	participated in the study design, data acquisition, advised lab work, and commented final version of the manuscript	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4397095	25875280	CX	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397095	25875280	CX	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397095	25875280	CYX	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397095	25875280	CYX	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397095	25875280	CYX	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397095	25875280	CYX	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397095	25875280	DGL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4397095	25875280	HZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397095	25875280	HZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397095	25875280	HZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397095	25875280	HZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397095	25875280	NFZ	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4397095	25875280	NFZ	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4397095	25875280	SLZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397095	25875280	SLZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397095	25875280	SLZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397095	25875280	SLZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6164892	30060547	All the authors	2	have critically discussed, read and approved the final manuscript	have critically discussed, read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6164892	30060547	J.A.G.Z.	2	were involved in direct patient care and wrote the manuscript	were involved in direct patient care and wrote the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6164892	30060547	Y.V.	2	were involved in direct patient care and wrote the manuscript	were involved in direct patient care and wrote the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3269999	22152156	MIW	2	designed the proposed method and analyzed the data statistically	designed the proposed method and analyzed the data statistically	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
3269999	22152156	MMS	2	carried out the experimental work	carried out the experimental work	Performed the experiments	Investigation	YES
3269999	22152156	MSR	2	proposed, planned and supervised the whole work	proposed, planned and supervised the whole work	Conceived and designed the experiments	Conceptualization|Supervision	YES
3269999	22152156	ZAS	2	coordinated the study and modified the text	coordinated the study and modified the text	-	Project administration	YES
5427679	28553306	HZ	2	conducted the phenotyping experiments|edited the manuscript	conducted the phenotyping experiments	Performed the experiments	Investigation	YES
5427679	28553306	HZ	2	conducted the phenotyping experiments|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5427679	28553306	MM	2	genotyped the population|provided the materials|edited the manuscript	genotyped the population	Performed the experiments	Investigation	YES
5427679	28553306	MM	2	genotyped the population|provided the materials|edited the manuscript	provided the materials	Contributed reagents/materials/analysis tools	Resources	YES
5427679	28553306	MM	2	genotyped the population|provided the materials|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5427679	28553306	MP	2	designed the study|provided the materials|edited the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5427679	28553306	MP	2	designed the study|provided the materials|edited the manuscript	provided the materials	Contributed reagents/materials/analysis tools	Resources	YES
5427679	28553306	MP	2	designed the study|provided the materials|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5427679	28553306	RT	2	provided the materials|edited the manuscript	provided the materials	Contributed reagents/materials/analysis tools	Resources	YES
5427679	28553306	RT	2	provided the materials|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5427679	28553306	SR	2	genotyped the population|edited the manuscript	genotyped the population	Performed the experiments	Investigation	YES
5427679	28553306	SR	2	genotyped the population|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5427679	28553306	TL	2	provided the materials	provided the materials	Contributed reagents/materials/analysis tools	Resources	YES
5427679	28553306	WL	2	designed the study|conducted the phenotyping experiments|performed the data analysis and wrote the manuscript|genotyped the population	designed the study	Conceived and designed the experiments	Methodology	YES
5427679	28553306	WL	2	designed the study|conducted the phenotyping experiments|performed the data analysis and wrote the manuscript|genotyped the population	conducted the phenotyping experiments	Performed the experiments	Investigation	YES
5427679	28553306	WL	2	designed the study|conducted the phenotyping experiments|performed the data analysis and wrote the manuscript|genotyped the population	performed the data analysis and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5427679	28553306	WL	2	designed the study|conducted the phenotyping experiments|performed the data analysis and wrote the manuscript|genotyped the population	genotyped the population	Performed the experiments	Investigation	YES
5427679	28553306	XC	2	provided the materials|edited the manuscript	provided the materials	Contributed reagents/materials/analysis tools	Resources	YES
5427679	28553306	XC	2	provided the materials|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
4994306	27549765	GMW	2	conceived of project, provided project oversight and direction|provided biological interpretation and prepared figures and tables|wrote the manuscript	conceived of project, provided project oversight and direction	Conceived and designed the experiments	Conceptualization|Supervision	YES
4994306	27549765	GMW	2	conceived of project, provided project oversight and direction|provided biological interpretation and prepared figures and tables|wrote the manuscript	provided biological interpretation and prepared figures and tables	Analyzed the data	Formal analysis|Visualization	YES
4994306	27549765	GMW	2	conceived of project, provided project oversight and direction|provided biological interpretation and prepared figures and tables|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4994306	27549765	JY	2	conceived of project, provided project oversight and direction|developed and ran the machine learning framework, prepared figures and tables|wrote the manuscript	conceived of project, provided project oversight and direction	Conceived and designed the experiments	Conceptualization|Supervision	YES
4994306	27549765	JY	2	conceived of project, provided project oversight and direction|developed and ran the machine learning framework, prepared figures and tables|wrote the manuscript	developed and ran the machine learning framework, prepared figures and tables	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
4994306	27549765	JY	2	conceived of project, provided project oversight and direction|developed and ran the machine learning framework, prepared figures and tables|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4994306	27549765	LY	2	provided biological interpretation and prepared figures and tables|performed ipa analysis|wrote the manuscript	provided biological interpretation and prepared figures and tables	Analyzed the data	Formal analysis|Visualization	YES
4994306	27549765	LY	2	provided biological interpretation and prepared figures and tables|performed ipa analysis|wrote the manuscript	performed ipa analysis	Performed the experiments	Investigation	YES
4994306	27549765	LY	2	provided biological interpretation and prepared figures and tables|performed ipa analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4994306	27549765	PP	2	initiated the case/control study design and coordinated the metabolomic data collection	initiated the case/control study design and coordinated the metabolomic data collection	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology|Project administration	YES
4994306	27549765	TS	2	initiated the case/control study design and coordinated the metabolomic data collection	initiated the case/control study design and coordinated the metabolomic data collection	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology|Project administration	YES
4994306	27549765	TY	2	developed and ran the machine learning framework, prepared figures and tables	developed and ran the machine learning framework, prepared figures and tables	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
4994306	27549765	VN	2	conceived of project, provided project oversight and direction	conceived of project, provided project oversight and direction	Conceived and designed the experiments	Conceptualization|Supervision	YES
4994306	27549765	WD	2	initiated the case/control study design and coordinated the metabolomic data collection	initiated the case/control study design and coordinated the metabolomic data collection	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology|Project administration	YES
4994306	27549765	YL	2	developed and ran the machine learning framework, prepared figures and tables|wrote the manuscript	developed and ran the machine learning framework, prepared figures and tables	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
4994306	27549765	YL	2	developed and ran the machine learning framework, prepared figures and tables|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3271044	22152091	JZ	2	participated in its design and coordination	participated in its design and coordination	Conceived and designed the experiments	Project administration	YES
6321502	30513888	C.M.S.	CRediT	methodology	methodology	Performed the experiments	Methodology	YES
6321502	30513888	G.K.	CRediT	Conceptualization	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6321502	30513888	M.P.	CRediT	software|data curation|writing--review and editing	software	Contributed reagents/materials/analysis tools	Software	YES
6321502	30513888	M.P.	CRediT	software|data curation|writing--review and editing	data curation	Analyzed the data	Data curation	YES
6321502	30513888	M.P.	CRediT	software|data curation|writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6321502	30513888	R.Y.	CRediT	Conceptualization|methodology|data curation|writing--original draft preparation	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6321502	30513888	R.Y.	CRediT	Conceptualization|methodology|data curation|writing--original draft preparation	methodology	Performed the experiments	Methodology	YES
6321502	30513888	R.Y.	CRediT	Conceptualization|methodology|data curation|writing--original draft preparation	data curation	Analyzed the data	Data curation	YES
6321502	30513888	R.Y.	CRediT	Conceptualization|methodology|data curation|writing--original draft preparation	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
4397096	25875863	AG	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397096	25875863	AG	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397096	25875863	AMS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397096	25875863	AMS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397096	25875863	AMS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397096	25875863	AMS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397096	25875863	GH	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397096	25875863	GH	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397096	25875863	JO	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397096	25875863	JO	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397096	25875863	JWF	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397096	25875863	JWF	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397096	25875863	MK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397096	25875863	MK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397096	25875863	MK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397096	25875863	MMC	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397096	25875863	MMC	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397096	25875863	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397096	25875863	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397096	25875863	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397096	25875863	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397096	25875863	MWM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397096	25875863	MWM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397096	25875863	MWM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397096	25875863	SG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4397096	25875863	SG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4397096	25875863	SG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4397096	25875863	SG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397096	25875863	TR	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4397096	25875863	TR	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6421559	30957011	AD	2	was involved partly in the experimental design and drafting the manuscript and revising it critically for important intellectual content	was involved partly in the experimental design and drafting the manuscript and revising it critically for important intellectual content	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft|Writing - Review & Editing	YES
6421559	30957011	BV	2	were instrumental in optimizing the fluid bed coating process parameters for the coating trials of potassium chloride and also the analysis of the coated potassium chloride	were instrumental in optimizing the fluid bed coating process parameters for the coating trials of potassium chloride and also the analysis of the coated potassium chloride	-	-	NO
6421559	30957011	MC	2	conceptualized the research work, designed the formulation development strategy and overall supervised the project	conceptualized the research work, designed the formulation development strategy and overall supervised the project	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology|Supervision	YES
6421559	30957011	SA	2	worked on the taste masking trials of potassium chloride, dry syrup dosage form development and analysis of the formulation including stability studies	worked on the taste masking trials of potassium chloride, dry syrup dosage form development and analysis of the formulation including stability studies	Conceived and designed the experiments|Performed the experiments	Conceptualization	YES
6421559	30957011	SS	2	were instrumental in optimizing the fluid bed coating process parameters for the coating trials of potassium chloride and also the analysis of the coated potassium chloride	were instrumental in optimizing the fluid bed coating process parameters for the coating trials of potassium chloride and also the analysis of the coated potassium chloride	-	-	NO
4994377	27549916	DPC	2	conducted qpcr analysis	conducted qpcr analysis	Performed the experiments	Investigation	YES
4994377	27549916	FKW	2	conducted qpcr analysis	conducted qpcr analysis	Performed the experiments	Investigation	YES
4994377	27549916	NXJ	2	designed the study and supervised the experiment|revised and improved the draft	designed the study and supervised the experiment	Conceived and designed the experiments	Methodology|Supervision	YES
4994377	27549916	NXJ	2	designed the study and supervised the experiment|revised and improved the draft	revised and improved the draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4994377	27549916	SWN	2	designed the study and supervised the experiment	designed the study and supervised the experiment	Conceived and designed the experiments	Methodology|Supervision	YES
4994377	27549916	WM	2	performed the bioinformatic analysis and prepared the manuscript	performed the bioinformatic analysis and prepared the manuscript	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4994377	27549916	YH	2	collected experimental materials	collected experimental materials	Performed the experiments	Investigation	YES
6164989	30049986	All	2	of them state that they have actively contributed to its elaboration both in the concept and in its design, as well as in the bibliographic review and its final revision	of them state that they have actively contributed to its elaboration both in the concept and in its design, as well as in the bibliographic review and its final revision	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Review & Editing	YES
4398053	25875198	AV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398053	25875198	AV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398053	25875198	AV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398053	25875198	AV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398053	25875198	AV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398053	25875198	JB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398053	25875198	JJF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398053	25875198	JJF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398053	25875198	JJF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398053	25875198	JJF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398053	25875198	KKWC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398053	25875198	KKWC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398053	25875198	LKH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398053	25875198	LKH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398053	25875198	LKH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398053	25875198	PM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
3275491	22264225	MFE	2	carried out the practical studies and write the manuscript	carried out the practical studies and write the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6321508	30513734	A.Y.	CRediT	formal analysis|resources	formal analysis	Analyzed the data	Formal analysis	YES
6321508	30513734	A.Y.	CRediT	formal analysis|resources	resources	Contributed reagents/materials/analysis tools	Resources	YES
6321508	30513734	H.K.	CRediT	Conceptualization|methodology|validation|formal analysis|resources|data curation|writing--original draft preparation|writing--review and editing|visualization|supervision|project administration|funding acquisition	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6321508	30513734	H.K.	CRediT	Conceptualization|methodology|validation|formal analysis|resources|data curation|writing--original draft preparation|writing--review and editing|visualization|supervision|project administration|funding acquisition	methodology	Performed the experiments	Methodology	YES
6321508	30513734	H.K.	CRediT	Conceptualization|methodology|validation|formal analysis|resources|data curation|writing--original draft preparation|writing--review and editing|visualization|supervision|project administration|funding acquisition	validation	Performed the experiments	Validation	YES
6321508	30513734	H.K.	CRediT	Conceptualization|methodology|validation|formal analysis|resources|data curation|writing--original draft preparation|writing--review and editing|visualization|supervision|project administration|funding acquisition	formal analysis	Analyzed the data	Formal analysis	YES
6321508	30513734	H.K.	CRediT	Conceptualization|methodology|validation|formal analysis|resources|data curation|writing--original draft preparation|writing--review and editing|visualization|supervision|project administration|funding acquisition	resources	Contributed reagents/materials/analysis tools	Resources	YES
6321508	30513734	H.K.	CRediT	Conceptualization|methodology|validation|formal analysis|resources|data curation|writing--original draft preparation|writing--review and editing|visualization|supervision|project administration|funding acquisition	data curation	Analyzed the data	Data curation	YES
6321508	30513734	H.K.	CRediT	Conceptualization|methodology|validation|formal analysis|resources|data curation|writing--original draft preparation|writing--review and editing|visualization|supervision|project administration|funding acquisition	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6321508	30513734	H.K.	CRediT	Conceptualization|methodology|validation|formal analysis|resources|data curation|writing--original draft preparation|writing--review and editing|visualization|supervision|project administration|funding acquisition	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6321508	30513734	H.K.	CRediT	Conceptualization|methodology|validation|formal analysis|resources|data curation|writing--original draft preparation|writing--review and editing|visualization|supervision|project administration|funding acquisition	visualization	Analyzed the data	Visualization	YES
6321508	30513734	H.K.	CRediT	Conceptualization|methodology|validation|formal analysis|resources|data curation|writing--original draft preparation|writing--review and editing|visualization|supervision|project administration|funding acquisition	supervision	-	Supervision	YES
6321508	30513734	H.K.	CRediT	Conceptualization|methodology|validation|formal analysis|resources|data curation|writing--original draft preparation|writing--review and editing|visualization|supervision|project administration|funding acquisition	project administration	-	Project administration	YES
6321508	30513734	H.K.	CRediT	Conceptualization|methodology|validation|formal analysis|resources|data curation|writing--original draft preparation|writing--review and editing|visualization|supervision|project administration|funding acquisition	funding acquisition	-	Funding acquisition	YES
6321508	30513734	H.S.	CRediT	investigation	investigation	Performed the experiments	Investigation	YES
6321508	30513734	M.M.	CRediT	formal analysis	formal analysis	Analyzed the data	Formal analysis	YES
6321508	30513734	N.H.	CRediT	investigation	investigation	Performed the experiments	Investigation	YES
6321508	30513734	R.T.	CRediT	investigation	investigation	Performed the experiments	Investigation	YES
6321508	30513734	S.M.	CRediT	methodology|validation|formal analysis|investigation|data curation|writing--original draft preparation	methodology	Performed the experiments	Methodology	YES
6321508	30513734	S.M.	CRediT	methodology|validation|formal analysis|investigation|data curation|writing--original draft preparation	validation	Performed the experiments	Validation	YES
6321508	30513734	S.M.	CRediT	methodology|validation|formal analysis|investigation|data curation|writing--original draft preparation	formal analysis	Analyzed the data	Formal analysis	YES
6321508	30513734	S.M.	CRediT	methodology|validation|formal analysis|investigation|data curation|writing--original draft preparation	investigation	Performed the experiments	Investigation	YES
6321508	30513734	S.M.	CRediT	methodology|validation|formal analysis|investigation|data curation|writing--original draft preparation	data curation	Analyzed the data	Data curation	YES
6321508	30513734	S.M.	CRediT	methodology|validation|formal analysis|investigation|data curation|writing--original draft preparation	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6321508	30513734	T.S.	CRediT	formal analysis	formal analysis	Analyzed the data	Formal analysis	YES
6214209	30393779	AUTHOR	2	designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
6214209	30393779	CONTRIBUTIONS	2	designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
6214209	30393779	ELN	2	designed the research|supervised data collection|wrote the article	designed the research	Conceived and designed the experiments	Methodology	YES
6214209	30393779	ELN	2	designed the research|supervised data collection|wrote the article	supervised data collection	Performed the experiments	Investigation|Supervision	YES
6214209	30393779	ELN	2	designed the research|supervised data collection|wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
6214209	30393779	JC	2	designed the research|analyzed data|wrote the article	designed the research	Conceived and designed the experiments	Methodology	YES
6214209	30393779	JC	2	designed the research|analyzed data|wrote the article	analyzed data	Analyzed the data	Formal analysis	YES
6214209	30393779	JC	2	designed the research|analyzed data|wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
4391645	25883973	Guo-Yi Zhang	2	contributed equally to this work	contributed equally to this work	-	-	NO
4391645	25883973	Ying Huang	2	contributed equally to this work	contributed equally to this work	-	-	NO
5430029	28555150	All authors	2	listed, have made substantial, direct and intellectual contribution to the work, and approved it for publication	listed, have made substantial, direct and intellectual contribution to the work, and approved it for publication	-	-	NO
3275501	22152129	AR	2	provided the x-ray studies and related hygroscopicity and structures	provided the x-ray studies and related hygroscopicity and structures	-	-	NO
3275501	22152129	JO	2	provided the hygroscopicity measurements including syntheses of the necessary amounts of all samples and revised the study	provided the hygroscopicity measurements including syntheses of the necessary amounts of all samples and revised the study	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Resources|Writing - Review & Editing	YES
3275501	22152129	RM	2	synthesised compound 8, prepared its crystal for x-ray analysis, provided dta and revised the study	synthesised compound 8, prepared its crystal for x-ray analysis, provided dta and revised the study	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
3275501	22152129	ZJ	2	has coordinated the study, carried out the synthesis of compounds 2-7, 9, prepared a single crystal of 7 for x-ray analysis and drafted the manuscript	has coordinated the study, carried out the synthesis of compounds 2-7, 9, prepared a single crystal of 7 for x-ray analysis and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Project administration|Writing - Original Draft	YES
6165057	29986388	F.G.D.	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6165057	29986388	F.G.D.	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
6165057	29986388	F.G.D.	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
6165057	29986388	F.G.D.	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6165057	29986388	J.E.C.	PLoS52	conceived and designed the experiments|analyzed the data|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6165057	29986388	J.E.C.	PLoS52	conceived and designed the experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
6165057	29986388	J.E.C.	PLoS52	conceived and designed the experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6165057	29986388	P.C.	PLoS52	performed the experiments|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
6165057	29986388	P.C.	PLoS52	performed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4994410	27550073	HPZ	2	provided the experimental environment and edited the manuscript	provided the experimental environment and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
4994410	27550073	JZG	2	performed part of the data analysis	performed part of the data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4994410	27550073	LJW	2	participated in the experimental design and surgical processes	participated in the experimental design and surgical processes	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4994410	27550073	LL	2	performed part of the data analysis	performed part of the data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4994410	27550073	SYZ	2	conceived the research, performed data analysis, and drafted the manuscript	conceived the research, performed data analysis, and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
4994410	27550073	TZ	2	participated in the experimental design and surgical processes	participated in the experimental design and surgical processes	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4994410	27550073	WZ	2	conducted the qpcr validation	conducted the qpcr validation	Performed the experiments	Investigation|Validation	YES
4994410	27550073	YD	2	conducted the animal experiments and sampling	conducted the animal experiments and sampling	Performed the experiments	Investigation	YES
4398054	25875921	C-CL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Interpretation of the results	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398054	25875921	C-CL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Interpretation of the results	Analyzed the data	Analyzed the data	Formal analysis	YES
4398054	25875921	C-CL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Interpretation of the results	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398054	25875921	C-CL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Interpretation of the results	Interpretation of the results	Analyzed the data	Formal analysis	YES
4398054	25875921	C-LC	PLoS5	Analyzed the data|Wrote the paper|Interpretation of the results	Analyzed the data	Analyzed the data	Formal analysis	YES
4398054	25875921	C-LC	PLoS5	Analyzed the data|Wrote the paper|Interpretation of the results	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398054	25875921	C-LC	PLoS5	Analyzed the data|Wrote the paper|Interpretation of the results	Interpretation of the results	Analyzed the data	Formal analysis	YES
4398054	25875921	C-PW	PLoS5	Interpretation of the results|Supervision over the project	Interpretation of the results	Analyzed the data	Formal analysis	YES
4398054	25875921	C-PW	PLoS5	Interpretation of the results|Supervision over the project	Supervision over the project	-	Supervision	YES
4398054	25875921	CYW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Interpretation of the results	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398054	25875921	CYW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Interpretation of the results	Analyzed the data	Analyzed the data	Formal analysis	YES
4398054	25875921	CYW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Interpretation of the results	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398054	25875921	CYW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Interpretation of the results	Interpretation of the results	Analyzed the data	Formal analysis	YES
4398054	25875921	J-YH	PLoS5	Interpretation of the results|Supervision over the project	Interpretation of the results	Analyzed the data	Formal analysis	YES
4398054	25875921	J-YH	PLoS5	Interpretation of the results|Supervision over the project	Supervision over the project	-	Supervision	YES
4398054	25875921	J-YW	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398054	25875921	J-YW	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4398054	25875921	LC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Interpretation of the results|Supervision over the project	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398054	25875921	LC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Interpretation of the results|Supervision over the project	Performed the experiments	Performed the experiments	Investigation	YES
4398054	25875921	LC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Interpretation of the results|Supervision over the project	Analyzed the data	Analyzed the data	Formal analysis	YES
4398054	25875921	LC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Interpretation of the results|Supervision over the project	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398054	25875921	LC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Interpretation of the results|Supervision over the project	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398054	25875921	LC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Interpretation of the results|Supervision over the project	Interpretation of the results	Analyzed the data	Formal analysis	YES
4398054	25875921	LC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Interpretation of the results|Supervision over the project	Supervision over the project	-	Supervision	YES
4398054	25875921	N-CT	PLoS5	Performed the experiments|Analyzed the data|Interpretation of the results	Performed the experiments	Performed the experiments	Investigation	YES
4398054	25875921	N-CT	PLoS5	Performed the experiments|Analyzed the data|Interpretation of the results	Analyzed the data	Analyzed the data	Formal analysis	YES
4398054	25875921	N-CT	PLoS5	Performed the experiments|Analyzed the data|Interpretation of the results	Interpretation of the results	Analyzed the data	Formal analysis	YES
4398054	25875921	S-LT	PLoS5	Contributed reagents/materials/analysis tools|Interpretation of the results|Supervision over the project	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398054	25875921	S-LT	PLoS5	Contributed reagents/materials/analysis tools|Interpretation of the results|Supervision over the project	Interpretation of the results	Analyzed the data	Formal analysis	YES
4398054	25875921	S-LT	PLoS5	Contributed reagents/materials/analysis tools|Interpretation of the results|Supervision over the project	Supervision over the project	-	Supervision	YES
4398054	25875921	T-TC	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6321516	30563073	J.R.	CRediT	Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6321516	30563073	L.M.	CRediT	Resources	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6321516	30563073	M.C.	CRediT	Data curation|Formal analysis|Writing--original draft	Data curation	Analyzed the data	Data curation	YES
6321516	30563073	M.C.	CRediT	Data curation|Formal analysis|Writing--original draft	Formal analysis	Analyzed the data	Formal analysis	YES
6321516	30563073	M.C.	CRediT	Data curation|Formal analysis|Writing--original draft	Writing--original draft	Wrote the paper	Writing - Original Draft	YES
6321516	30563073	X.L.	CRediT	Conceptualization|Methodology	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6321516	30563073	X.L.	CRediT	Conceptualization|Methodology	Methodology	Performed the experiments	Methodology	YES
6321516	30563073	X.W.	CRediT	Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
5430036	28555145	CWT	PLoS52	conceived and designed the experiments, analyzed the data and wrote the manuscript	conceived and designed the experiments, analyzed the data and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
5430036	28555145	SKH	PLoS52	performed the experiments|conceived and designed the experiments, analyzed the data and wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5430036	28555145	SKH	PLoS52	performed the experiments|conceived and designed the experiments, analyzed the data and wrote the manuscript	conceived and designed the experiments, analyzed the data and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
4398316	25875812	EDB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Formulated research question and selection criteria|Performed the literature search and study selection	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398316	25875812	EDB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Formulated research question and selection criteria|Performed the literature search and study selection	Analyzed the data	Analyzed the data	Formal analysis	YES
4398316	25875812	EDB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Formulated research question and selection criteria|Performed the literature search and study selection	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398316	25875812	EDB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Formulated research question and selection criteria|Performed the literature search and study selection	Formulated research question and selection criteria	Conceived and designed the experiments	Conceptualization	YES
4398316	25875812	EDB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Formulated research question and selection criteria|Performed the literature search and study selection	Performed the literature search and study selection	Performed the experiments	Formal analysis|Investigation	YES
4398316	25875812	PV	PLoS5	Conceived and designed the experiments|Wrote the paper|Formulated research question and selection criteria	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398316	25875812	PV	PLoS5	Conceived and designed the experiments|Wrote the paper|Formulated research question and selection criteria	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398316	25875812	PV	PLoS5	Conceived and designed the experiments|Wrote the paper|Formulated research question and selection criteria	Formulated research question and selection criteria	Conceived and designed the experiments	Conceptualization	YES
4398316	25875812	TD	PLoS5	Conceived and designed the experiments|Analyzed the data|Formulated research question and selection criteria|Performed the literature search and study selection	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398316	25875812	TD	PLoS5	Conceived and designed the experiments|Analyzed the data|Formulated research question and selection criteria|Performed the literature search and study selection	Analyzed the data	Analyzed the data	Formal analysis	YES
4398316	25875812	TD	PLoS5	Conceived and designed the experiments|Analyzed the data|Formulated research question and selection criteria|Performed the literature search and study selection	Formulated research question and selection criteria	Conceived and designed the experiments	Conceptualization	YES
4398316	25875812	TD	PLoS5	Conceived and designed the experiments|Analyzed the data|Formulated research question and selection criteria|Performed the literature search and study selection	Performed the literature search and study selection	Performed the experiments	Formal analysis|Investigation	YES
4398316	25875812	VC	PLoS5	Conceived and designed the experiments|Formulated research question and selection criteria	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398316	25875812	VC	PLoS5	Conceived and designed the experiments|Formulated research question and selection criteria	Formulated research question and selection criteria	Conceived and designed the experiments	Conceptualization	YES
6165110	29933556	All authors	2	reviewed and approved the final version of the manuscript	reviewed and approved the final version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
6165110	29933556	B.R.G.B.	2	provided care to the patient	provided care to the patient	Performed the experiments	Investigation	YES
6165110	29933556	E.S.P.	2	collected data and biological samples for arbovirus infection diagnosis and patient follow up	collected data and biological samples for arbovirus infection diagnosis and patient follow up	Performed the experiments	Investigation	YES
6165110	29933556	K.R.S.	2	provided care to the patient	provided care to the patient	Performed the experiments	Investigation	YES
6165110	29933556	M.G.C.	2	collected data and biological samples for arbovirus infection diagnosis and patient follow up	collected data and biological samples for arbovirus infection diagnosis and patient follow up	Performed the experiments	Investigation	YES
6165110	29933556	M.M.A.	2	provided care to the patient	provided care to the patient	Performed the experiments	Investigation	YES
6165110	29933556	R.B.S.	2	provided care to the patient	provided care to the patient	Performed the experiments	Investigation	YES
3275514	22185518	BBS	2	designed the study, carried out the synthesis, characterization, interpretation and drafted the manuscript	designed the study, carried out the synthesis, characterization, interpretation and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
3275514	22185518	SPS	2	participated in the design of the study, synthesis, characterization and carried out pharmacological and statistical work	participated in the design of the study, synthesis, characterization and carried out pharmacological and statistical work	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
6321522	30551601	E.C.-G.	2	participated in the study design, performed most experiments and wrote the original draft	participated in the study design, performed most experiments and wrote the original draft	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
6321522	30551601	F.J.O.-E.	2	participated in the conceptualization, design of experiments, data analysis, supervision, writing and editing	participated in the conceptualization, design of experiments, data analysis, supervision, writing and editing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Supervision|Writing - Review & Editing	YES
6321522	30551601	J.L.G.-A.	2	participated in the conceptualization, design of experiments, data analysis, supervision, writing and editing	participated in the conceptualization, design of experiments, data analysis, supervision, writing and editing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Supervision|Writing - Review & Editing	YES
6321522	30551601	M.B.D.-C.	2	participated in the data analysis and the review and editing of the manuscript	participated in the data analysis and the review and editing of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
6321522	30551601	S.A.-I.	2	participated in the study design, performed most experiments and wrote the original draft	participated in the study design, performed most experiments and wrote the original draft	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
4995656	27552984	BD	2	helped with rna extraction and qrt pcr	helped with rna extraction and qrt pcr	Performed the experiments	Investigation	YES
4995656	27552984	FC	2	conceived the study, participated in its design and contributed to revisions of the manuscript	conceived the study, participated in its design and contributed to revisions of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
4995656	27552984	JG	2	helped with rna extraction and qrt pcr	helped with rna extraction and qrt pcr	Performed the experiments	Investigation	YES
4995656	27552984	JJ	2	conceived the study, participated in its design and contributed to revisions of the manuscript	conceived the study, participated in its design and contributed to revisions of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
4995656	27552984	JS	2	participated in experiment materials preparation	participated in experiment materials preparation	Performed the experiments	Investigation	YES
4995656	27552984	LR	2	contributed to bioinformatics analysis and writing of the manuscript	contributed to bioinformatics analysis and writing of the manuscript	Wrote the paper	Formal analysis|Writing - Original Draft	YES
4995656	27552984	SC	2	conceived the study, participated in its design and contributed to revisions of the manuscript	conceived the study, participated in its design and contributed to revisions of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
4995656	27552984	TL	2	contributed to bioinformatics analysis and writing of the manuscript	contributed to bioinformatics analysis and writing of the manuscript	Wrote the paper	Formal analysis|Writing - Original Draft	YES
4995656	27552984	YC	2	participated in experiment materials preparation	participated in experiment materials preparation	Performed the experiments	Investigation	YES
4398317	25876154	AD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398317	25876154	AD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398317	25876154	AD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398317	25876154	AD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398317	25876154	AD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398317	25876154	AM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398317	25876154	AM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398317	25876154	AM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398317	25876154	SKR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398317	25876154	SKR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398317	25876154	SKR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398317	25876154	SKR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398317	25876154	SKR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398317	25876154	SPR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398317	25876154	SPR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398317	25876154	SPR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398317	25876154	SPR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398317	25876154	SPR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6321530	30463290	All authors	2	reviewed the final manuscript	reviewed the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6321530	30463290	M.T.	2	prepared and drafted the article	prepared and drafted the article	Wrote the paper	Writing - Original Draft	YES
3275517	22214530	AA	2	participated in optimizing of the assay conditions and its validation	participated in optimizing of the assay conditions and its validation	Performed the experiments	Investigation|Validation	YES
3275517	22214530	ID	2	designed the study, participated in the results discussion and prepared the manuscript	designed the study, participated in the results discussion and prepared the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3275517	22214530	NA	2	participated in optimizing of the assay conditions and its validation	participated in optimizing of the assay conditions and its validation	Performed the experiments	Investigation|Validation	YES
3275517	22214530	NK	2	participated in conducting the assay validation and analysis of dosage forms	participated in conducting the assay validation and analysis of dosage forms	Performed the experiments	Investigation|Validation	YES
3275517	22214530	TW	2	participated in conducting the assay validation and analysis of dosage forms	participated in conducting the assay validation and analysis of dosage forms	Performed the experiments	Investigation|Validation	YES
5430052	28555142	All authors	PLoS52	reviewed and approved the manuscript	reviewed and approved the manuscript	Wrote the paper	Writing - Review & Editing	YES
5430052	28555142	JS	PLoS52	supervised the work and revised the manuscript	supervised the work and revised the manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
5430052	28555142	MD	PLoS52	conceived and designed the experiments, analyzed the data and wrote the manuscript|performed the experiments	conceived and designed the experiments, analyzed the data and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
5430052	28555142	MD	PLoS52	conceived and designed the experiments, analyzed the data and wrote the manuscript|performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5430052	28555142	MZ	PLoS52	conceived and designed the experiments, analyzed the data and wrote the manuscript|supervised the work and revised the manuscript	conceived and designed the experiments, analyzed the data and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
5430052	28555142	MZ	PLoS52	conceived and designed the experiments, analyzed the data and wrote the manuscript|supervised the work and revised the manuscript	supervised the work and revised the manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
5430052	28555142	TC	PLoS52	performed the bioinformatic in situ analysis	performed the bioinformatic in situ analysis	Performed the experiments	Formal analysis|Investigation	YES
6165210	29996536	A.A.	2	was responsible for study concept and design, analysis and interpretation of data, critical revision of the manuscript for important intellectual content, and supervision of the research project	was responsible for study concept and design, analysis and interpretation of data, critical revision of the manuscript for important intellectual content, and supervision of the research project	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Supervision|Writing - Review & Editing	YES
6165210	29996536	A.A.L.	2	was responsible for study concept and design, acquisition of data, analysis and interpretation of data, drafting of the manuscript, critical revision of the manuscript for important intellectual content, and statistical analysis	was responsible for study concept and design, acquisition of data, analysis and interpretation of data, drafting of the manuscript, critical revision of the manuscript for important intellectual content, and statistical analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
6165210	29996536	A.E.T.	2	was responsible for study concept, acquisition of data, analysis and interpretation of data, and statistical analysis	was responsible for study concept, acquisition of data, analysis and interpretation of data, and statistical analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation	YES
6165210	29996536	D.H.	2	was responsible for analysis and interpretation of data and critical revision of the manuscript for important intellectual content	was responsible for analysis and interpretation of data and critical revision of the manuscript for important intellectual content	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
6165210	29996536	G.C.	2	were responsible for study concept and design, analysis and interpretation of data, drafting, critical revision of the manuscript for important intellectual content, and statistical analysis	were responsible for study concept and design, analysis and interpretation of data, drafting, critical revision of the manuscript for important intellectual content, and statistical analysis	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
6165210	29996536	J.C.T.	2	were responsible for study concept and design, analysis and interpretation of data, drafting, critical revision of the manuscript for important intellectual content, and statistical analysis	were responsible for study concept and design, analysis and interpretation of data, drafting, critical revision of the manuscript for important intellectual content, and statistical analysis	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
6165210	29996536	S.N.	2	was responsible for study concept and design, analysis and interpretation of data, drafting, critical revision of the manuscript for important intellectual content, and statistical analysis	was responsible for study concept and design, analysis and interpretation of data, drafting, critical revision of the manuscript for important intellectual content, and statistical analysis	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
6165210	29996536	X.S.C.	2	were responsible for study concept and design, analysis and interpretation of data, drafting, critical revision of the manuscript for important intellectual content, and statistical analysis	were responsible for study concept and design, analysis and interpretation of data, drafting, critical revision of the manuscript for important intellectual content, and statistical analysis	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
4995758	27554097	DM	2	reviewed the manuscript and designed the simulation study	reviewed the manuscript and designed the simulation study	Conceived and designed the experiments|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
4995758	27554097	FG	2	did the data preprocessing, the lr analysis, simulation study and drafted the manuscript	did the data preprocessing, the lr analysis, simulation study and drafted the manuscript	Analyzed the data|Wrote the paper	Data curation|Formal analysis|Writing - Original Draft	YES
4995758	27554097	HH	2	adviced on the study design and helped to draft the manuscript	adviced on the study design and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4995758	27554097	JRH	2	participated in the study design and coordination	participated in the study design and coordination	Conceived and designed the experiments	Methodology|Project administration	YES
4995758	27554097	PLSR	2	and bayz	and bayz	-	-	NO
3277491	22142453	VSP	5	contributed for synthesis|contributed for photophysical study under the guidance NS|contributed for photophysical study under the guidance NS	contributed for synthesis	-	-	NO
3277491	22142453	VSP	5	contributed for synthesis|contributed for photophysical study under the guidance NS|contributed for photophysical study under the guidance NS	contributed for photophysical study under the guidance NS	-	Supervision	YES
3277491	22142453	VSP	5	contributed for synthesis|contributed for photophysical study under the guidance NS|contributed for photophysical study under the guidance NS	contributed for photophysical study under the guidance NS	-	Supervision	YES
4398318	25875656	JB	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398318	25875656	JB	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398318	25875656	JH	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4398318	25875656	KK	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4398318	25875656	KKK	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398318	25875656	KKK	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6321545	30423797	A.B.	CRediT	investigation	investigation	Performed the experiments	Investigation	YES
6321545	30423797	A.M.	CRediT	investigation	investigation	Performed the experiments	Investigation	YES
6321545	30423797	D.B.	CRediT	investigation	investigation	Performed the experiments	Investigation	YES
6321545	30423797	E.M.C.-C.	CRediT	methodology|validation|formal analysis|investigation|data curation|writing--original draft preparation|writing--review and editing|visualization|supervision	methodology	Performed the experiments	Methodology	YES
6321545	30423797	E.M.C.-C.	CRediT	methodology|validation|formal analysis|investigation|data curation|writing--original draft preparation|writing--review and editing|visualization|supervision	validation	Performed the experiments	Validation	YES
6321545	30423797	E.M.C.-C.	CRediT	methodology|validation|formal analysis|investigation|data curation|writing--original draft preparation|writing--review and editing|visualization|supervision	formal analysis	Analyzed the data	Formal analysis	YES
6321545	30423797	E.M.C.-C.	CRediT	methodology|validation|formal analysis|investigation|data curation|writing--original draft preparation|writing--review and editing|visualization|supervision	investigation	Performed the experiments	Investigation	YES
6321545	30423797	E.M.C.-C.	CRediT	methodology|validation|formal analysis|investigation|data curation|writing--original draft preparation|writing--review and editing|visualization|supervision	data curation	Analyzed the data	Data curation	YES
6321545	30423797	E.M.C.-C.	CRediT	methodology|validation|formal analysis|investigation|data curation|writing--original draft preparation|writing--review and editing|visualization|supervision	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6321545	30423797	E.M.C.-C.	CRediT	methodology|validation|formal analysis|investigation|data curation|writing--original draft preparation|writing--review and editing|visualization|supervision	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6321545	30423797	E.M.C.-C.	CRediT	methodology|validation|formal analysis|investigation|data curation|writing--original draft preparation|writing--review and editing|visualization|supervision	visualization	Analyzed the data	Visualization	YES
6321545	30423797	E.M.C.-C.	CRediT	methodology|validation|formal analysis|investigation|data curation|writing--original draft preparation|writing--review and editing|visualization|supervision	supervision	-	Supervision	YES
6321545	30423797	E.R.	CRediT	Conceptualization|resources|supervision|funding acquisition	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6321545	30423797	E.R.	CRediT	Conceptualization|resources|supervision|funding acquisition	resources	Contributed reagents/materials/analysis tools	Resources	YES
6321545	30423797	E.R.	CRediT	Conceptualization|resources|supervision|funding acquisition	supervision	-	Supervision	YES
6321545	30423797	E.R.	CRediT	Conceptualization|resources|supervision|funding acquisition	funding acquisition	-	Funding acquisition	YES
6321545	30423797	I.S.-K.	CRediT	resources|supervision	resources	Contributed reagents/materials/analysis tools	Resources	YES
6321545	30423797	I.S.-K.	CRediT	resources|supervision	supervision	-	Supervision	YES
6321545	30423797	J.J.V.-D.	CRediT	investigation|resources	investigation	Performed the experiments	Investigation	YES
6321545	30423797	J.J.V.-D.	CRediT	investigation|resources	resources	Contributed reagents/materials/analysis tools	Resources	YES
6321545	30423797	J.M.	CRediT	investigation	investigation	Performed the experiments	Investigation	YES
6321545	30423797	K.P.	CRediT	resources|supervision	resources	Contributed reagents/materials/analysis tools	Resources	YES
6321545	30423797	K.P.	CRediT	resources|supervision	supervision	-	Supervision	YES
6321545	30423797	L.C.	CRediT	investigation	investigation	Performed the experiments	Investigation	YES
6321545	30423797	L.S.	CRediT	investigation	investigation	Performed the experiments	Investigation	YES
6321545	30423797	M.C.R.	CRediT	resources|supervision	resources	Contributed reagents/materials/analysis tools	Resources	YES
6321545	30423797	M.C.R.	CRediT	resources|supervision	supervision	-	Supervision	YES
6321545	30423797	M.D.	CRediT	resources|supervision	resources	Contributed reagents/materials/analysis tools	Resources	YES
6321545	30423797	M.D.	CRediT	resources|supervision	supervision	-	Supervision	YES
6321545	30423797	M.R.	CRediT	resources|supervision	resources	Contributed reagents/materials/analysis tools	Resources	YES
6321545	30423797	M.R.	CRediT	resources|supervision	supervision	-	Supervision	YES
6321545	30423797	P.F.	CRediT	Conceptualization|funding acquisition	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6321545	30423797	P.F.	CRediT	Conceptualization|funding acquisition	funding acquisition	-	Funding acquisition	YES
6321545	30423797	P.P.	CRediT	investigation	investigation	Performed the experiments	Investigation	YES
6321545	30423797	P.U.	CRediT	methodology|investigation	methodology	Performed the experiments	Methodology	YES
6321545	30423797	P.U.	CRediT	methodology|investigation	investigation	Performed the experiments	Investigation	YES
6321545	30423797	R.E.S.	CRediT	resources|supervision	resources	Contributed reagents/materials/analysis tools	Resources	YES
6321545	30423797	R.E.S.	CRediT	resources|supervision	supervision	-	Supervision	YES
6321545	30423797	X.F.-B.	CRediT	Conceptualization|formal analysis|resources|writing--review and editing|supervision|project administration|funding acquisition	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6321545	30423797	X.F.-B.	CRediT	Conceptualization|formal analysis|resources|writing--review and editing|supervision|project administration|funding acquisition	formal analysis	Analyzed the data	Formal analysis	YES
6321545	30423797	X.F.-B.	CRediT	Conceptualization|formal analysis|resources|writing--review and editing|supervision|project administration|funding acquisition	resources	Contributed reagents/materials/analysis tools	Resources	YES
6321545	30423797	X.F.-B.	CRediT	Conceptualization|formal analysis|resources|writing--review and editing|supervision|project administration|funding acquisition	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6321545	30423797	X.F.-B.	CRediT	Conceptualization|formal analysis|resources|writing--review and editing|supervision|project administration|funding acquisition	supervision	-	Supervision	YES
6321545	30423797	X.F.-B.	CRediT	Conceptualization|formal analysis|resources|writing--review and editing|supervision|project administration|funding acquisition	project administration	-	Project administration	YES
6321545	30423797	X.F.-B.	CRediT	Conceptualization|formal analysis|resources|writing--review and editing|supervision|project administration|funding acquisition	funding acquisition	-	Funding acquisition	YES
6373418	30631964	A.H.	PLoS52	performed all uv-vis spectroscopy, optical cryomicroscopy|wrote the paper	performed all uv-vis spectroscopy, optical cryomicroscopy	Performed the experiments	Investigation	YES
6373418	30631964	A.H.	PLoS52	performed all uv-vis spectroscopy, optical cryomicroscopy|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6373418	30631964	G.H.	PLoS52	supported the sample preparation|supervised the work	supported the sample preparation	Performed the experiments	Investigation	YES
6373418	30631964	G.H.	PLoS52	supported the sample preparation|supervised the work	supervised the work	-	Supervision	YES
6373418	30631964	SEC	PLoS52	alc measurements	alc measurements	Performed the experiments	Investigation	YES
6373418	30631964	T.L.	PLoS52	wrote the paper|supervised the work	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6373418	30631964	T.L.	PLoS52	wrote the paper|supervised the work	supervised the work	-	Supervision	YES
6165230	30096779	A.F.	2	helped search pubmed database for studies	helped search pubmed database for studies	Contributed reagents/materials/analysis tools	Software	YES
6165230	30096779	C.G.	2	reviewed the studies and the paper	reviewed the studies and the paper	Wrote the paper	Writing - Review & Editing	YES
6165230	30096779	C.T.	2	helped search pubmed database for studies	helped search pubmed database for studies	Contributed reagents/materials/analysis tools	Software	YES
6165230	30096779	D.P.	2	reviewed the studies and the paper	reviewed the studies and the paper	Wrote the paper	Writing - Review & Editing	YES
5430053	28555144	MK	2	conceived and conducted the research, performed the statistical analyses, and wrote the manuscript	conceived and conducted the research, performed the statistical analyses, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
3284442	22206681	All three authors	2	initiated and designed the study	initiated and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3284442	22206681	DMC	2	contributed equally to data analyses and to finalizing the manuscript	contributed equally to data analyses and to finalizing the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
3284442	22206681	MMP	2	contributed equally to data analyses and to finalizing the manuscript	contributed equally to data analyses and to finalizing the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
3284442	22206681	VSK	2	contributed equally to data analyses and to finalizing the manuscript	contributed equally to data analyses and to finalizing the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
4997668	27558469	AX	2	gave the genetic and biological statistical analysis	gave the genetic and biological statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4997668	27558469	DY	2	performed the data analysis	performed the data analysis	Analyzed the data	Formal analysis	YES
4997668	27558469	HZ	2	conceived the study|performed the data analysis|coordinated the sampling of material	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4997668	27558469	HZ	2	conceived the study|performed the data analysis|coordinated the sampling of material	performed the data analysis	Analyzed the data	Formal analysis	YES
4997668	27558469	HZ	2	conceived the study|performed the data analysis|coordinated the sampling of material	coordinated the sampling of material	Performed the experiments	Investigation|Project administration	YES
4997668	27558469	JS	2	conceived the study|carried out the manuscript and writing work	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4997668	27558469	JS	2	conceived the study|carried out the manuscript and writing work	carried out the manuscript and writing work	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4997668	27558469	QQ	2	performed the data analysis	performed the data analysis	Analyzed the data	Formal analysis	YES
4997668	27558469	YZ	2	conceived the study|carried out the manuscript and writing work|performed the data analysis	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4997668	27558469	YZ	2	conceived the study|carried out the manuscript and writing work|performed the data analysis	carried out the manuscript and writing work	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4997668	27558469	YZ	2	conceived the study|carried out the manuscript and writing work|performed the data analysis	performed the data analysis	Analyzed the data	Formal analysis	YES
4997668	27558469	ZJ	2	performed the data analysis	performed the data analysis	Analyzed the data	Formal analysis	YES
6165240	30200449	A.A.	2	contributed to data collection	contributed to data collection	Performed the experiments	Investigation	YES
6165240	30200449	A.B.	2	contributed to the study conception and design|contributed to project administration	contributed to the study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6165240	30200449	A.B.	2	contributed to the study conception and design|contributed to project administration	contributed to project administration	-	Project administration	YES
6165240	30200449	A.D.	2	contributed to data collection	contributed to data collection	Performed the experiments	Investigation	YES
6165240	30200449	A.L.	2	contributed to data collection	contributed to data collection	Performed the experiments	Investigation	YES
6165240	30200449	All authors	2	contributed to the writing and critical review of the manuscript	contributed to the writing and critical review of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6165240	30200449	B.A.	2	contributed to project administration	contributed to project administration	-	Project administration	YES
6165240	30200449	C.S.	2	contributed to data collection	contributed to data collection	Performed the experiments	Investigation	YES
6165240	30200449	D.M.D.	2	contributed to data collection	contributed to data collection	Performed the experiments	Investigation	YES
6165240	30200449	D.P.	2	contributed to data collection	contributed to data collection	Performed the experiments	Investigation	YES
6165240	30200449	L.M.P.	2	contributed to data collection	contributed to data collection	Performed the experiments	Investigation	YES
6165240	30200449	N.G.	2	contributed to data collection	contributed to data collection	Performed the experiments	Investigation	YES
6165240	30200449	R.L.S.	2	contributed to project administration|contributed to data collection	contributed to project administration	-	Project administration	YES
6165240	30200449	R.L.S.	2	contributed to project administration|contributed to data collection	contributed to data collection	Performed the experiments	Investigation	YES
6165240	30200449	S.C.	2	contributed to data collection	contributed to data collection	Performed the experiments	Investigation	YES
6165240	30200449	S.G.	2	contributed to data collection	contributed to data collection	Performed the experiments	Investigation	YES
6165240	30200449	S.H.	2	contributed to the study conception and design|contributed to project administration|contributed to the analysis and interpretation of the data	contributed to the study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6165240	30200449	S.H.	2	contributed to the study conception and design|contributed to project administration|contributed to the analysis and interpretation of the data	contributed to project administration	-	Project administration	YES
6165240	30200449	S.H.	2	contributed to the study conception and design|contributed to project administration|contributed to the analysis and interpretation of the data	contributed to the analysis and interpretation of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6165240	30200449	W.H.	2	contributed to the analysis and interpretation of the data	contributed to the analysis and interpretation of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6321552	30322148	A.S.	1	Conducted experiments|Performed data analysis	Conducted experiments	Performed the experiments	Investigation	YES
6321552	30322148	A.S.	1	Conducted experiments|Performed data analysis	Performed data analysis	Analyzed the data	Formal analysis	YES
6321552	30322148	B.O.-A.	1	Participated in research design|Conducted experiments|Performed data analysis|Wrote or contributed to the writing of the manuscript	Participated in research design	Conceived and designed the experiments	-	YES
6321552	30322148	B.O.-A.	1	Participated in research design|Conducted experiments|Performed data analysis|Wrote or contributed to the writing of the manuscript	Conducted experiments	Performed the experiments	Investigation	YES
6321552	30322148	B.O.-A.	1	Participated in research design|Conducted experiments|Performed data analysis|Wrote or contributed to the writing of the manuscript	Performed data analysis	Analyzed the data	Formal analysis	YES
6321552	30322148	B.O.-A.	1	Participated in research design|Conducted experiments|Performed data analysis|Wrote or contributed to the writing of the manuscript	Wrote or contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
6321552	30322148	K.W.T.	1	Conducted experiments|Performed data analysis	Conducted experiments	Performed the experiments	Investigation	YES
6321552	30322148	K.W.T.	1	Conducted experiments|Performed data analysis	Performed data analysis	Analyzed the data	Formal analysis	YES
6321552	30322148	S.H.I.	1	Participated in research design|Conducted experiments|Contributed new reagents or analytic tools|Performed data analysis|Wrote or contributed to the writing of the manuscript	Participated in research design	Conceived and designed the experiments	-	YES
6321552	30322148	S.H.I.	1	Participated in research design|Conducted experiments|Contributed new reagents or analytic tools|Performed data analysis|Wrote or contributed to the writing of the manuscript	Conducted experiments	Performed the experiments	Investigation	YES
6321552	30322148	S.H.I.	1	Participated in research design|Conducted experiments|Contributed new reagents or analytic tools|Performed data analysis|Wrote or contributed to the writing of the manuscript	Contributed new reagents or analytic tools	Contributed reagents/materials/analysis tools	Resources	YES
6321552	30322148	S.H.I.	1	Participated in research design|Conducted experiments|Contributed new reagents or analytic tools|Performed data analysis|Wrote or contributed to the writing of the manuscript	Performed data analysis	Analyzed the data	Formal analysis	YES
6321552	30322148	S.H.I.	1	Participated in research design|Conducted experiments|Contributed new reagents or analytic tools|Performed data analysis|Wrote or contributed to the writing of the manuscript	Wrote or contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
3284456	22122971	AM	2	participated in the sequence alignment, carried out the chemical constitution assays and drafted the manuscript	participated in the sequence alignment, carried out the chemical constitution assays and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3284456	22122971	DM	2	conceived and participated in the design of the study	conceived and participated in the design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3284456	22122971	SK	2	carried out the practical works and drafted the manuscript	carried out the practical works and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4398319	25875012	ASK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398319	25875012	ASK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398319	25875012	ASK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398319	25875012	ASK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398319	25875012	GM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398319	25875012	GM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398319	25875012	GM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398319	25875012	GM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398319	25875012	GM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398319	25875012	GN	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398319	25875012	GN	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398319	25875012	GN	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398319	25875012	LCK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398319	25875012	LCK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398319	25875012	LCK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398319	25875012	PNB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398319	25875012	PNB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398319	25875012	PNB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5430056	28555152	BY	2	did the field work	did the field work	Performed the experiments	Investigation	YES
5430056	28555152	FT	2	did the field work	did the field work	Performed the experiments	Investigation	YES
5430056	28555152	SF	2	did the mc-fish	did the mc-fish	-	-	NO
5430056	28555152	TR	2	designed this work|did the mc-fish|did the resistance analyze|did the field work|wrote the manuscript	designed this work	Conceived and designed the experiments	-	YES
5430056	28555152	TR	2	designed this work|did the mc-fish|did the resistance analyze|did the field work|wrote the manuscript	did the mc-fish	-	-	NO
5430056	28555152	TR	2	designed this work|did the mc-fish|did the resistance analyze|did the field work|wrote the manuscript	did the resistance analyze	Analyzed the data	Formal analysis	YES
5430056	28555152	TR	2	designed this work|did the mc-fish|did the resistance analyze|did the field work|wrote the manuscript	did the field work	Performed the experiments	Investigation	YES
5430056	28555152	TR	2	designed this work|did the mc-fish|did the resistance analyze|did the field work|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5430056	28555152	ZL	2	designed this work|wrote the manuscript	designed this work	Conceived and designed the experiments	-	YES
5430056	28555152	ZL	2	designed this work|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5430056	28555152	ZR	2	did the resistance analyze|did the field work	did the resistance analyze	Analyzed the data	Formal analysis	YES
5430056	28555152	ZR	2	did the resistance analyze|did the field work	did the field work	Performed the experiments	Investigation	YES
5430056	28555152	ZT	2	did the mc-fish	did the mc-fish	-	-	NO
6165367	30227612	G.S.	CRediT	Conceptualization|Writing-review & editing|Supervision	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6165367	30227612	G.S.	CRediT	Conceptualization|Writing-review & editing|Supervision	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6165367	30227612	G.S.	CRediT	Conceptualization|Writing-review & editing|Supervision	Supervision	-	Supervision	YES
6165367	30227612	J.A.	CRediT	Conceptualization|Methodology|Data curation|Software|Resources|Validation|Writing-review & editing|Supervision	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6165367	30227612	J.A.	CRediT	Conceptualization|Methodology|Data curation|Software|Resources|Validation|Writing-review & editing|Supervision	Methodology	Performed the experiments	Methodology	YES
6165367	30227612	J.A.	CRediT	Conceptualization|Methodology|Data curation|Software|Resources|Validation|Writing-review & editing|Supervision	Data curation	Analyzed the data	Data curation	YES
6165367	30227612	J.A.	CRediT	Conceptualization|Methodology|Data curation|Software|Resources|Validation|Writing-review & editing|Supervision	Software	Contributed reagents/materials/analysis tools	Software	YES
6165367	30227612	J.A.	CRediT	Conceptualization|Methodology|Data curation|Software|Resources|Validation|Writing-review & editing|Supervision	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6165367	30227612	J.A.	CRediT	Conceptualization|Methodology|Data curation|Software|Resources|Validation|Writing-review & editing|Supervision	Validation	Performed the experiments	Validation	YES
6165367	30227612	J.A.	CRediT	Conceptualization|Methodology|Data curation|Software|Resources|Validation|Writing-review & editing|Supervision	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6165367	30227612	J.A.	CRediT	Conceptualization|Methodology|Data curation|Software|Resources|Validation|Writing-review & editing|Supervision	Supervision	-	Supervision	YES
6165367	30227612	M.B.	CRediT	Validation|Formal analysis|Investigation|Writing-original draft preparation	Validation	Performed the experiments	Validation	YES
6165367	30227612	M.B.	CRediT	Validation|Formal analysis|Investigation|Writing-original draft preparation	Formal analysis	Analyzed the data	Formal analysis	YES
6165367	30227612	M.B.	CRediT	Validation|Formal analysis|Investigation|Writing-original draft preparation	Investigation	Performed the experiments	Investigation	YES
6165367	30227612	M.B.	CRediT	Validation|Formal analysis|Investigation|Writing-original draft preparation	Writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
4997765	27558348	AV	2	wrote or critically revised the manuscript|produced or analyzed data, or interpreted results	wrote or critically revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4997765	27558348	AV	2	wrote or critically revised the manuscript|produced or analyzed data, or interpreted results	produced or analyzed data, or interpreted results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4997765	27558348	All authors	2	made substantial contributions to the conception and design of this study|gave approval for the submission of this manuscript	made substantial contributions to the conception and design of this study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4997765	27558348	All authors	2	made substantial contributions to the conception and design of this study|gave approval for the submission of this manuscript	gave approval for the submission of this manuscript	-	-	NO
4997765	27558348	BB	2	wrote or critically revised the manuscript|produced or analyzed data, or interpreted results	wrote or critically revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4997765	27558348	BB	2	wrote or critically revised the manuscript|produced or analyzed data, or interpreted results	produced or analyzed data, or interpreted results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4997765	27558348	BF	2	wrote or critically revised the manuscript|produced or analyzed data, or interpreted results	wrote or critically revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4997765	27558348	BF	2	wrote or critically revised the manuscript|produced or analyzed data, or interpreted results	produced or analyzed data, or interpreted results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4997765	27558348	ES	2	produced or analyzed data, or interpreted results	produced or analyzed data, or interpreted results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4997765	27558348	JL	2	produced or analyzed data, or interpreted results	produced or analyzed data, or interpreted results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4997765	27558348	KN	2	produced or analyzed data, or interpreted results	produced or analyzed data, or interpreted results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4997765	27558348	LC	2	wrote or critically revised the manuscript|produced or analyzed data, or interpreted results	wrote or critically revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4997765	27558348	LC	2	wrote or critically revised the manuscript|produced or analyzed data, or interpreted results	produced or analyzed data, or interpreted results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4997765	27558348	MR	2	produced or analyzed data, or interpreted results	produced or analyzed data, or interpreted results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4997765	27558348	RCJ	2	wrote or critically revised the manuscript	wrote or critically revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6321554	30388840	E.P.	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper|revised and edited the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6321554	30388840	E.P.	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper|revised and edited the paper	performed the experiments	Performed the experiments	Investigation	YES
6321554	30388840	E.P.	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper|revised and edited the paper	analyzed the data	Analyzed the data	Formal analysis	YES
6321554	30388840	E.P.	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper|revised and edited the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6321554	30388840	E.P.	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper|revised and edited the paper	revised and edited the paper	Wrote the paper	Writing - Review & Editing	YES
6321554	30388840	J.L.R.S.	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|revised and edited the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6321554	30388840	J.L.R.S.	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|revised and edited the paper	performed the experiments	Performed the experiments	Investigation	YES
6321554	30388840	J.L.R.S.	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|revised and edited the paper	analyzed the data	Analyzed the data	Formal analysis	YES
6321554	30388840	J.L.R.S.	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|revised and edited the paper	revised and edited the paper	Wrote the paper	Writing - Review & Editing	YES
6321554	30388840	M.J.	PLoS52	performed the experiments|revised and edited the paper	performed the experiments	Performed the experiments	Investigation	YES
6321554	30388840	M.J.	PLoS52	performed the experiments|revised and edited the paper	revised and edited the paper	Wrote the paper	Writing - Review & Editing	YES
6321554	30388840	M.K.	PLoS52	performed the experiments|revised and edited the paper	performed the experiments	Performed the experiments	Investigation	YES
6321554	30388840	M.K.	PLoS52	performed the experiments|revised and edited the paper	revised and edited the paper	Wrote the paper	Writing - Review & Editing	YES
6321554	30388840	M.S.	PLoS52	contributed reagents/materials/analysis tools|revised and edited the paper	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
6321554	30388840	M.S.	PLoS52	contributed reagents/materials/analysis tools|revised and edited the paper	revised and edited the paper	Wrote the paper	Writing - Review & Editing	YES
3285059	22145683	MP	2	carried out the work described in the paper, under|read and approved the final manuscript	carried out the work described in the paper, under	Performed the experiments	Investigation	YES
3285059	22145683	MP	2	carried out the work described in the paper, under|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
3285059	22145683	SM	2	supervised the under|read and approved the final manuscript	supervised the under	-	Supervision	YES
3285059	22145683	SM	2	supervised the under|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
3287153	22293530	All authors	2	contributed to data analyses and to finalizing the manuscript	contributed to data analyses and to finalizing the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
3287153	22293530	GPL	2	who drafted the manuscript	who drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
3287153	22293530	SPL	2	initiated and all authors designed the study	initiated and all authors designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6321556	30297674	F.-Y.H.	CRediT	Data curation|Formal analysis|Project administration|Writing-original draft	Data curation	Analyzed the data	Data curation	YES
6321556	30297674	F.-Y.H.	CRediT	Data curation|Formal analysis|Project administration|Writing-original draft	Formal analysis	Analyzed the data	Formal analysis	YES
6321556	30297674	F.-Y.H.	CRediT	Data curation|Formal analysis|Project administration|Writing-original draft	Project administration	-	Project administration	YES
6321556	30297674	F.-Y.H.	CRediT	Data curation|Formal analysis|Project administration|Writing-original draft	Writing-original draft	Wrote the paper	Writing - Original Draft	YES
6321556	30297674	H.-M.L.	CRediT	Methodology	Methodology	Performed the experiments	Methodology	YES
6321556	30297674	P.-A.H.	CRediT	Formal analysis|Methodology	Formal analysis	Analyzed the data	Formal analysis	YES
6321556	30297674	P.-A.H.	CRediT	Formal analysis|Methodology	Methodology	Performed the experiments	Methodology	YES
6321556	30297674	S.-S.H.	CRediT	Formal analysis|Methodology	Formal analysis	Analyzed the data	Formal analysis	YES
6321556	30297674	S.-S.H.	CRediT	Formal analysis|Methodology	Methodology	Performed the experiments	Methodology	YES
6321556	30297674	S.-W.T.	CRediT	Data curation|Formal analysis|Writing-original draft	Data curation	Analyzed the data	Data curation	YES
6321556	30297674	S.-W.T.	CRediT	Data curation|Formal analysis|Writing-original draft	Formal analysis	Analyzed the data	Formal analysis	YES
6321556	30297674	S.-W.T.	CRediT	Data curation|Formal analysis|Writing-original draft	Writing-original draft	Wrote the paper	Writing - Original Draft	YES
6321556	30297674	W.-X.Y.	CRediT	Formal analysis|Methodology	Formal analysis	Analyzed the data	Formal analysis	YES
6321556	30297674	W.-X.Y.	CRediT	Formal analysis|Methodology	Methodology	Performed the experiments	Methodology	YES
6321556	30297674	Y.-W.H.	CRediT	Methodology	Methodology	Performed the experiments	Methodology	YES
4398320	25875176	AL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398320	25875176	AL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398320	25875176	AL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398320	25875176	AL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398320	25875176	KB	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4398320	25875176	KI	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398320	25875176	MG	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4398320	25875176	NS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398320	25875176	SN	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4398320	25875176	SN	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
6165409	30037152	A.N.	2	carried out part of the statistical analyses	carried out part of the statistical analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6165409	30037152	H.H.	2	carried out part of the statistical analyses	carried out part of the statistical analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6165409	30037152	T.N.	2	carried out part of the statistical analyses	carried out part of the statistical analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5430057	28555151	AX	PLoS52	analyzed the evaluation of disease resistance	analyzed the evaluation of disease resistance	Analyzed the data	Formal analysis	YES
5430057	28555151	DC	PLoS52	performed hybridization	performed hybridization	Performed the experiments	Investigation	YES
5430057	28555151	GF	PLoS52	participated in the study conception and design|wrote the manuscript	participated in the study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5430057	28555151	GF	PLoS52	participated in the study conception and design|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5430057	28555151	HL	PLoS52	contributed to dna extraction and molecular marker identification|analyzed the evaluation of disease resistance	contributed to dna extraction and molecular marker identification	Performed the experiments	Investigation	YES
5430057	28555151	HL	PLoS52	contributed to dna extraction and molecular marker identification|analyzed the evaluation of disease resistance	analyzed the evaluation of disease resistance	Analyzed the data	Formal analysis	YES
5430057	28555151	JC	PLoS52	participated in the study conception and design|wrote the manuscript	participated in the study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5430057	28555151	JC	PLoS52	participated in the study conception and design|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5430057	28555151	WC	PLoS52	performed hybridization	performed hybridization	Performed the experiments	Investigation	YES
5430057	28555151	YD	PLoS52	participated in the study conception and design|contributed to dna extraction and molecular marker identification|performed hybridization|analyzed the evaluation of disease resistance|analyzed the data|wrote the manuscript	participated in the study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5430057	28555151	YD	PLoS52	participated in the study conception and design|contributed to dna extraction and molecular marker identification|performed hybridization|analyzed the evaluation of disease resistance|analyzed the data|wrote the manuscript	contributed to dna extraction and molecular marker identification	Performed the experiments	Investigation	YES
5430057	28555151	YD	PLoS52	participated in the study conception and design|contributed to dna extraction and molecular marker identification|performed hybridization|analyzed the evaluation of disease resistance|analyzed the data|wrote the manuscript	performed hybridization	Performed the experiments	Investigation	YES
5430057	28555151	YD	PLoS52	participated in the study conception and design|contributed to dna extraction and molecular marker identification|performed hybridization|analyzed the evaluation of disease resistance|analyzed the data|wrote the manuscript	analyzed the evaluation of disease resistance	Analyzed the data	Formal analysis	YES
5430057	28555151	YD	PLoS52	participated in the study conception and design|contributed to dna extraction and molecular marker identification|performed hybridization|analyzed the evaluation of disease resistance|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5430057	28555151	YD	PLoS52	participated in the study conception and design|contributed to dna extraction and molecular marker identification|performed hybridization|analyzed the evaluation of disease resistance|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5430057	28555151	YG	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5430057	28555151	YaD	PLoS52	contributed to dna extraction and molecular marker identification|analyzed the data	contributed to dna extraction and molecular marker identification	Performed the experiments	Investigation	YES
5430057	28555151	YaD	PLoS52	contributed to dna extraction and molecular marker identification|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
3292812	22305477	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
3292812	22305477	MA	2	participated in the design and collection of data and experimental work and analysis	participated in the design and collection of data and experimental work and analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
3292812	22305477	MRK	2	has made a substantial contribution to conception and design, interpretation of data, drafting and revising the manuscript for intellectual content	has made a substantial contribution to conception and design, interpretation of data, drafting and revising the manuscript for intellectual content	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Resources|Writing - Original Draft|Writing - Review & Editing	YES
3292812	22305477	RAK	2	made a significant contribution to acquisition of data, analysis, drafting of the manuscript	made a significant contribution to acquisition of data, analysis, drafting of the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft	YES
3292812	22305477	SS	2	participated in the design and collection of data and analysis	participated in the design and collection of data and analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6165478	30200425	A.B.	2	analyzed the samples|wrote the manuscript	analyzed the samples	Analyzed the data	Formal analysis	YES
6165478	30200425	A.B.	2	analyzed the samples|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6165478	30200425	A.C.	2	analyzed the samples	analyzed the samples	Analyzed the data	Formal analysis	YES
6165478	30200425	M.M.-H.	2	analyzed the samples|wrote the manuscript	analyzed the samples	Analyzed the data	Formal analysis	YES
6165478	30200425	M.M.-H.	2	analyzed the samples|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6165478	30200425	R.d.l.T.	2	conceived the experiment, and wrote and critically revised the manuscript	conceived the experiment, and wrote and critically revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
4398323	25874951	KF	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398323	25874951	KH	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398323	25874951	MS	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4398323	25874951	OH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398323	25874951	T. Takeuchi	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398323	25874951	T. Tanigawa	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4398323	25874951	T. Tanigawa	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398323	25874951	TA	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398323	25874951	TA	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398323	25874951	TW	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398323	25874951	TW	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398323	25874951	TW	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398323	25874951	TW	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398323	25874951	TY	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398323	25874951	YN	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398323	25874951	YS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4997766	27558222	CM	2	conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4997766	27558222	FG	2	conceived the study|performed pathway analysis and interpreted the pathway and rna seq data	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4997766	27558222	FG	2	conceived the study|performed pathway analysis and interpreted the pathway and rna seq data	performed pathway analysis and interpreted the pathway and rna seq data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4997766	27558222	SS	2	performed the lamprey parasitism on the lake trout and obtained the liver samples for transcriptomic analysis	performed the lamprey parasitism on the lake trout and obtained the liver samples for transcriptomic analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6321570	30423822	J.K.	CRediT	Conceptualization|Methodology|Formal analysis|Investigation|Data curation|Writing-original draft preparation|Writing-review & editing|Project administration	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6321570	30423822	J.K.	CRediT	Conceptualization|Methodology|Formal analysis|Investigation|Data curation|Writing-original draft preparation|Writing-review & editing|Project administration	Methodology	Performed the experiments	Methodology	YES
6321570	30423822	J.K.	CRediT	Conceptualization|Methodology|Formal analysis|Investigation|Data curation|Writing-original draft preparation|Writing-review & editing|Project administration	Formal analysis	Analyzed the data	Formal analysis	YES
6321570	30423822	J.K.	CRediT	Conceptualization|Methodology|Formal analysis|Investigation|Data curation|Writing-original draft preparation|Writing-review & editing|Project administration	Investigation	Performed the experiments	Investigation	YES
6321570	30423822	J.K.	CRediT	Conceptualization|Methodology|Formal analysis|Investigation|Data curation|Writing-original draft preparation|Writing-review & editing|Project administration	Data curation	Analyzed the data	Data curation	YES
6321570	30423822	J.K.	CRediT	Conceptualization|Methodology|Formal analysis|Investigation|Data curation|Writing-original draft preparation|Writing-review & editing|Project administration	Writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
6321570	30423822	J.K.	CRediT	Conceptualization|Methodology|Formal analysis|Investigation|Data curation|Writing-original draft preparation|Writing-review & editing|Project administration	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6321570	30423822	J.K.	CRediT	Conceptualization|Methodology|Formal analysis|Investigation|Data curation|Writing-original draft preparation|Writing-review & editing|Project administration	Project administration	-	Project administration	YES
6321570	30423822	P.R.	CRediT	Conceptualization|Supervision|Funding acquisition	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6321570	30423822	P.R.	CRediT	Conceptualization|Supervision|Funding acquisition	Supervision	-	Supervision	YES
6321570	30423822	P.R.	CRediT	Conceptualization|Supervision|Funding acquisition	Funding acquisition	-	Funding acquisition	YES
6321570	30423822	R.J.	CRediT	Conceptualization|Data curation|Writing-review & editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6321570	30423822	R.J.	CRediT	Conceptualization|Data curation|Writing-review & editing	Data curation	Analyzed the data	Data curation	YES
6321570	30423822	R.J.	CRediT	Conceptualization|Data curation|Writing-review & editing	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
5430062	28555147	GH	2	contributed to editing manuscript	contributed to editing manuscript	Wrote the paper	Writing - Review & Editing	YES
5430062	28555147	MA	2	supervised development of work, provided guidance throughout the project, and edited manuscript	supervised development of work, provided guidance throughout the project, and edited manuscript	Wrote the paper	Supervision|Writing - Original Draft|Writing - Review & Editing	YES
5430062	28555147	TT	2	prepared input data, performed models and interpreted results, wrote manuscript and acted as corresponding author	prepared input data, performed models and interpreted results, wrote manuscript and acted as corresponding author	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4398324	25874640	CF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398324	25874640	CF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398324	25874640	CF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398324	25874640	CF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398324	25874640	CF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398324	25874640	JMY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398324	25874640	JMY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398324	25874640	JMY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398324	25874640	JMY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398324	25874640	JMY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398324	25874640	JY	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4398324	25874640	JY	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4398324	25874640	JY	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398324	25874640	KKS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398324	25874640	LVW	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398324	25874640	LVW	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398324	25874640	QZ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398324	25874640	RC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
3114697	21592368	All authors	2	contributed to the manuscript and approved the final version	contributed to the manuscript and approved the final version	-	-	NO
3114697	21592368	CC	2	were involved in conducting the literature search, data extraction, data synthesis and analysis	were involved in conducting the literature search, data extraction, data synthesis and analysis	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
3114697	21592368	DO	2	conceptualized the review and led the writing	conceptualized the review and led the writing	Conceived and designed the experiments|Wrote the paper	Conceptualization	YES
3114697	21592368	KU	2	were involved in conducting the literature search, data extraction, data synthesis and analysis	were involved in conducting the literature search, data extraction, data synthesis and analysis	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
3114697	21592368	LC	2	was involved in interpreting the findings	was involved in interpreting the findings	Analyzed the data	Formal analysis	YES
6165515	30201879	A.A.	2	supervised the project	supervised the project	-	Supervision	YES
6165515	30201879	A.A.L.	2	contributed significantly to data collection, compilation	contributed significantly to data collection, compilation	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
6165515	30201879	B.J.P.	2	prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
6165515	30201879	D.K.	2	contributed significantly to data collection, compilation	contributed significantly to data collection, compilation	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
6165515	30201879	G.C.	2	contributed significantly to data collection, compilation	contributed significantly to data collection, compilation	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
6165515	30201879	N.D.S.	2	contributed significantly to data collection, compilation	contributed significantly to data collection, compilation	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
6165515	30201879	S.S.	2	contributed significantly to data collection, compilation	contributed significantly to data collection, compilation	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
6165515	30201879	U.I.	2	contributed significantly to data collection, compilation	contributed significantly to data collection, compilation	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
6165515	30201879	W.K.	2	contributed significantly to data collection, compilation	contributed significantly to data collection, compilation	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
3292994	22277722	AA	2	carried out the experimental work	carried out the experimental work	Performed the experiments	Investigation	YES
3292994	22277722	FB	2	proposed, planned and supervised the whole work	proposed, planned and supervised the whole work	Conceived and designed the experiments	Conceptualization|Supervision	YES
3292994	22277722	MN	2	carried out the experimental work	carried out the experimental work	Performed the experiments	Investigation	YES
3292994	22277722	NE	2	designed the proposed method, analysed the data stastistically and wrote the manuscript and collect the literature review	designed the proposed method, analysed the data stastistically and wrote the manuscript and collect the literature review	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
3292994	22277722	YI	2	carried out the experimental work	carried out the experimental work	Performed the experiments	Investigation	YES
5000459	27561606	ATW	2	made further modifications to the phamerator code, edited the phamerator instructions, gathered and analyzed data, and generated figures|created the phamerator database used in this analysis	made further modifications to the phamerator code, edited the phamerator instructions, gathered and analyzed data, and generated figures	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Formal analysis|Investigation|Supervision|Visualization|Writing - Review & Editing	YES
5000459	27561606	ATW	2	made further modifications to the phamerator code, edited the phamerator instructions, gathered and analyzed data, and generated figures|created the phamerator database used in this analysis	created the phamerator database used in this analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Software	YES
5000459	27561606	All authors	2	contributed to editing of the manuscript	contributed to editing of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5000459	27561606	BDM	2	were responsible for the design and coordination of the research|drafted the manuscript and wrote the phamerator instructions|made further modifications to the phamerator code, edited the phamerator instructions, gathered and analyzed data, and generated figures	were responsible for the design and coordination of the research	Conceived and designed the experiments	Methodology|Project administration	YES
5000459	27561606	BDM	2	were responsible for the design and coordination of the research|drafted the manuscript and wrote the phamerator instructions|made further modifications to the phamerator code, edited the phamerator instructions, gathered and analyzed data, and generated figures	drafted the manuscript and wrote the phamerator instructions	Wrote the paper	Supervision|Writing - Original Draft	YES
5000459	27561606	BDM	2	were responsible for the design and coordination of the research|drafted the manuscript and wrote the phamerator instructions|made further modifications to the phamerator code, edited the phamerator instructions, gathered and analyzed data, and generated figures	made further modifications to the phamerator code, edited the phamerator instructions, gathered and analyzed data, and generated figures	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Formal analysis|Investigation|Supervision|Visualization|Writing - Review & Editing	YES
5000459	27561606	JHG	2	were responsible for the design and coordination of the research|edited extensively	were responsible for the design and coordination of the research	Conceived and designed the experiments	Methodology|Project administration	YES
5000459	27561606	JHG	2	were responsible for the design and coordination of the research|edited extensively	edited extensively	Wrote the paper	Writing - Review & Editing	YES
5000459	27561606	SH	2	were responsible for the design and coordination of the research|edited extensively	were responsible for the design and coordination of the research	Conceived and designed the experiments	Methodology|Project administration	YES
5000459	27561606	SH	2	were responsible for the design and coordination of the research|edited extensively	edited extensively	Wrote the paper	Writing - Review & Editing	YES
6321573	30332804	Both authors	2	contributed equally in all phases of this manuscript preparation and have approved its final version	contributed equally in all phases of this manuscript preparation and have approved its final version	Wrote the paper	Writing - Original Draft	YES
3295732	22305461	IAD	2	proposed the subject, designed the study, participated in the results discussion and revised the manuscript	proposed the subject, designed the study, participated in the results discussion and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
3295732	22305461	MAE	2	conducted the optimization of the assay conditions and its validation and prepared the draft version of the manuscript	conducted the optimization of the assay conditions and its validation and prepared the draft version of the manuscript	Performed the experiments|Wrote the paper	Investigation|Validation|Writing - Original Draft	YES
3295732	22305461	MMA	2	participated in the assay design, results discussion, and preparing the manuscript	participated in the assay design, results discussion, and preparing the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3115833	21548988	All authors	2	contributed to the concept of the work and reviewed the paper	contributed to the concept of the work and reviewed the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
3115833	21548988	DLT	2	chiefly wrote the paper	chiefly wrote the paper	Wrote the paper	Writing - Original Draft	YES
3115833	21548988	DT	2	performed the research that contributed to the figures cited	performed the research that contributed to the figures cited	Performed the experiments	Investigation|Visualization	YES
3115833	21548988	MSK	2	performed the research that contributed to the figures cited	performed the research that contributed to the figures cited	Performed the experiments	Investigation|Visualization	YES
4398325	25874551	B. White	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Discussed results|Edited the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398325	25874551	B. White	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Discussed results|Edited the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398325	25874551	B. White	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Discussed results|Edited the paper	Discussed results	-	-	NO
4398325	25874551	B. White	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Discussed results|Edited the paper	Edited the paper	Wrote the paper	Writing - Review & Editing	YES
4398325	25874551	B. Wilson	PLoS5	Conceived and designed the experiments|Discussed results|Edited the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398325	25874551	B. Wilson	PLoS5	Conceived and designed the experiments|Discussed results|Edited the paper	Discussed results	-	-	NO
4398325	25874551	B. Wilson	PLoS5	Conceived and designed the experiments|Discussed results|Edited the paper	Edited the paper	Wrote the paper	Writing - Review & Editing	YES
4398325	25874551	CJY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Discussed results|Edited the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398325	25874551	CJY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Discussed results|Edited the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398325	25874551	CJY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Discussed results|Edited the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398325	25874551	CJY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Discussed results|Edited the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398325	25874551	CJY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Discussed results|Edited the paper	Discussed results	-	-	NO
4398325	25874551	CJY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Discussed results|Edited the paper	Edited the paper	Wrote the paper	Writing - Review & Editing	YES
4398325	25874551	GER	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Discussed results|Edited the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398325	25874551	GER	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Discussed results|Edited the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398325	25874551	GER	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Discussed results|Edited the paper	Discussed results	-	-	NO
4398325	25874551	GER	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Discussed results|Edited the paper	Edited the paper	Wrote the paper	Writing - Review & Editing	YES
4398325	25874551	KMK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Discussed results|Edited the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398325	25874551	KMK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Discussed results|Edited the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398325	25874551	KMK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Discussed results|Edited the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398325	25874551	KMK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Discussed results|Edited the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398325	25874551	KMK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Discussed results|Edited the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398325	25874551	KMK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Discussed results|Edited the paper	Discussed results	-	-	NO
4398325	25874551	KMK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Discussed results|Edited the paper	Edited the paper	Wrote the paper	Writing - Review & Editing	YES
4398325	25874551	NG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Discussed results|Edited the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398325	25874551	NG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Discussed results|Edited the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398325	25874551	NG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Discussed results|Edited the paper	Discussed results	-	-	NO
4398325	25874551	NG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Discussed results|Edited the paper	Edited the paper	Wrote the paper	Writing - Review & Editing	YES
4398325	25874551	VDR	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Discussed results|Edited the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398325	25874551	VDR	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Discussed results|Edited the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398325	25874551	VDR	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Discussed results|Edited the paper	Discussed results	-	-	NO
4398325	25874551	VDR	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Discussed results|Edited the paper	Edited the paper	Wrote the paper	Writing - Review & Editing	YES
6313317	30274355	All the authors	2	included in this study contributed to data collection, review of the literature in the pubmed dataset and in drawing conclusions about the best clinical therapies in the prevention of myopia	included in this study contributed to data collection, review of the literature in the pubmed dataset and in drawing conclusions about the best clinical therapies in the prevention of myopia	Performed the experiments	Formal analysis|Investigation	YES
5000498	27561358	AR	2	performed the statistical analyses on the gene set and wrote the manuscript	performed the statistical analyses on the gene set and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5000498	27561358	JHC	2	modeled, evaluated and annotated gene constructions, and performed summary analyses	modeled, evaluated and annotated gene constructions, and performed summary analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5000498	27561358	JHW	2	conceived the study, provided scientific guidance and participated in the writing of the manuscript	conceived the study, provided scientific guidance and participated in the writing of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Supervision|Writing - Original Draft	YES
5000498	27561358	JKC	2	conceived the study, provided scientific guidance and participated in the writing of the manuscript	conceived the study, provided scientific guidance and participated in the writing of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Supervision|Writing - Original Draft	YES
5000498	27561358	TS	2	provided the sequencing data and assisted in drafting the manuscript	provided the sequencing data and assisted in drafting the manuscript	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Resources|Writing - Original Draft	YES
3389716	22792084	Jia Qin	2	contributed equally to this work	contributed equally to this work	-	-	NO
3389716	22792084	Roberto Reif	2	contributed equally to this work	contributed equally to this work	-	-	NO
3389716	22792084	The authors	2	contributed equally to this work	contributed equally to this work	-	-	NO
3116452	21569393	CM	2	contributed to the study conception and design|reviewed the paper	contributed to the study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
3116452	21569393	CM	2	contributed to the study conception and design|reviewed the paper	reviewed the paper	Wrote the paper	Writing - Review & Editing	YES
3116452	21569393	DK	2	contributed to the study conception and design|collected and analyzed data|contributed to the writing of the paper	contributed to the study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
3116452	21569393	DK	2	contributed to the study conception and design|collected and analyzed data|contributed to the writing of the paper	collected and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3116452	21569393	DK	2	contributed to the study conception and design|collected and analyzed data|contributed to the writing of the paper	contributed to the writing of the paper	Wrote the paper	Writing - Original Draft	YES
3116452	21569393	DOB	2	contributed to the study conception and design|collected and analyzed data|wrote the first draft of the paper	contributed to the study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
3116452	21569393	DOB	2	contributed to the study conception and design|collected and analyzed data|wrote the first draft of the paper	collected and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3116452	21569393	DOB	2	contributed to the study conception and design|collected and analyzed data|wrote the first draft of the paper	wrote the first draft of the paper	Wrote the paper	Writing - Original Draft	YES
3116452	21569393	JG	2	contributed to the study conception and design|collected and analyzed data|wrote the first draft of the paper	contributed to the study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
3116452	21569393	JG	2	contributed to the study conception and design|collected and analyzed data|wrote the first draft of the paper	collected and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3116452	21569393	JG	2	contributed to the study conception and design|collected and analyzed data|wrote the first draft of the paper	wrote the first draft of the paper	Wrote the paper	Writing - Original Draft	YES
3116452	21569393	PDC	2	contributed to the study conception and design|contributed to the writing of the paper	contributed to the study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
3116452	21569393	PDC	2	contributed to the study conception and design|contributed to the writing of the paper	contributed to the writing of the paper	Wrote the paper	Writing - Original Draft	YES
3116452	21569393	PRH	2	reviewed the paper	reviewed the paper	Wrote the paper	Writing - Review & Editing	YES
3116452	21569393	SJ	2	reviewed the paper	reviewed the paper	Wrote the paper	Writing - Review & Editing	YES
3296636	22353684	AA	2	participated in the design of the study, carried out the experimental work and manuscript drafting	participated in the design of the study, carried out the experimental work and manuscript drafting	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
3296636	22353684	AM	2	coordinated the study and modified the text	coordinated the study and modified the text	-	Project administration	YES
3296636	22353684	FB	2	participated in the design of this study and analyzed the experimental data	participated in the design of this study and analyzed the experimental data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
3296636	22353684	MH	2	proposed and supervised the program, and participated in data analysis and draft revision	proposed and supervised the program, and participated in data analysis and draft revision	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
4398326	25874695	CD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398326	25874695	CD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398326	25874695	CD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398326	25874695	CD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398326	25874695	CD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398326	25874695	JL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398326	25874695	JL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4398326	25874695	JL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398326	25874695	ZS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4398326	25874695	ZS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
6313319	30249980	A.A.	CRediT	Writing-original draft preparation|Writing-review & editing|Supervision	Writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
6313319	30249980	A.A.	CRediT	Writing-original draft preparation|Writing-review & editing|Supervision	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6313319	30249980	A.A.	CRediT	Writing-original draft preparation|Writing-review & editing|Supervision	Supervision	-	Supervision	YES
6313319	30249980	B.J.P.	CRediT	Writing-original draft preparation	Writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
6313319	30249980	D.K.	CRediT	Writing-review & editing	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6313319	30249980	G.C.	CRediT	Writing-original draft preparation	Writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
6313319	30249980	N.D.S.	CRediT	Writing-original draft preparation	Writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
6313319	30249980	N.J.	CRediT	Writing-original draft preparation	Writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
6313319	30249980	S.S.	CRediT	Writing-original draft preparation	Writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
6313319	30249980	U.I.	CRediT	Writing-original draft preparation	Writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
6313319	30249980	W.K.	CRediT	Writing-original draft preparation	Writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
5000506	27561422	BJB	CRediT	Methodology|Software|Resources	Methodology	Performed the experiments	Methodology	YES
5000506	27561422	BJB	CRediT	Methodology|Software|Resources	Software	Contributed reagents/materials/analysis tools	Software	YES
5000506	27561422	BJB	CRediT	Methodology|Software|Resources	Resources	Contributed reagents/materials/analysis tools	Resources	YES
5000506	27561422	CM	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
5000506	27561422	DJP	CRediT	Resources|Supervision|Funding acquisition	Resources	Contributed reagents/materials/analysis tools	Resources	YES
5000506	27561422	DJP	CRediT	Resources|Supervision|Funding acquisition	Supervision	-	Supervision	YES
5000506	27561422	DJP	CRediT	Resources|Supervision|Funding acquisition	Funding acquisition	-	Funding acquisition	YES
5000506	27561422	IT	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
5000506	27561422	JT	CRediT	Conceptualization|Validation|Investigation|Visualization	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
5000506	27561422	JT	CRediT	Conceptualization|Validation|Investigation|Visualization	Validation	Performed the experiments	Validation	YES
5000506	27561422	JT	CRediT	Conceptualization|Validation|Investigation|Visualization	Investigation	Performed the experiments	Investigation	YES
5000506	27561422	JT	CRediT	Conceptualization|Validation|Investigation|Visualization	Visualization	Analyzed the data	Visualization	YES
5000506	27561422	QP	CRediT	Methodology|Software|Validation	Methodology	Performed the experiments	Methodology	YES
5000506	27561422	QP	CRediT	Methodology|Software|Validation	Software	Contributed reagents/materials/analysis tools	Software	YES
5000506	27561422	QP	CRediT	Methodology|Software|Validation	Validation	Performed the experiments	Validation	YES
5000506	27561422	SEG	CRediT	Conceptualization|Resources|Visualization|Supervision|Funding acquisition	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
5000506	27561422	SEG	CRediT	Conceptualization|Resources|Visualization|Supervision|Funding acquisition	Resources	Contributed reagents/materials/analysis tools	Resources	YES
5000506	27561422	SEG	CRediT	Conceptualization|Resources|Visualization|Supervision|Funding acquisition	Visualization	Analyzed the data	Visualization	YES
5000506	27561422	SEG	CRediT	Conceptualization|Resources|Visualization|Supervision|Funding acquisition	Supervision	-	Supervision	YES
5000506	27561422	SEG	CRediT	Conceptualization|Resources|Visualization|Supervision|Funding acquisition	Funding acquisition	-	Funding acquisition	YES
6321592	30445768	A.C.	2	analyzed the data and wrote the paper	analyzed the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6321592	30445768	A.C.B.	2	performed the nmr experiments	performed the nmr experiments	Performed the experiments	Investigation	YES
6321592	30445768	A.D.	2	performed the nmr experiments	performed the nmr experiments	Performed the experiments	Investigation	YES
6321592	30445768	A.R.	2	performed the synthesis and the preliminary characterization	performed the synthesis and the preliminary characterization	Performed the experiments	Investigation	YES
6321592	30445768	C.B.	2	performed the nmr experiments	performed the nmr experiments	Performed the experiments	Investigation	YES
6321592	30445768	C.S.	2	performed the dls analyses and the cytotoxicity evaluation	performed the dls analyses and the cytotoxicity evaluation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6321592	30445768	D.P.	2	performed the mwd characterization	performed the mwd characterization	Performed the experiments	Investigation	YES
6321592	30445768	E.P.	2	performed the tem analyses	performed the tem analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6321592	30445768	F.C.	2	performed the synthesis and the preliminary characterization	performed the synthesis and the preliminary characterization	Performed the experiments	Investigation	YES
6321592	30445768	F.S.	2	performed the maldi-tof experiments	performed the maldi-tof experiments	Performed the experiments	Investigation	YES
6321592	30445768	Germano Giuliani	2	performed the synthesis and the preliminary characterization	performed the synthesis and the preliminary characterization	Performed the experiments	Investigation	YES
6321592	30445768	Gianluca Giorgi	2	performed the crystallography studies	performed the crystallography studies	Performed the experiments	Investigation	YES
6321592	30445768	Giorgio Grisci	2	performed the synthesis and the preliminary characterization	performed the synthesis and the preliminary characterization	Performed the experiments	Investigation	YES
6321592	30445768	M.C.	2	performed the wide-angle x-ray diffraction experiments	performed the wide-angle x-ray diffraction experiments	Performed the experiments	Investigation	YES
6321592	30445768	M.G.	2	performed the tem analyses	performed the tem analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6321592	30445768	M.L.	2	performed the dls analyses and the cytotoxicity evaluation	performed the dls analyses and the cytotoxicity evaluation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6321592	30445768	M.P.	2	performed the synthesis and the preliminary characterization	performed the synthesis and the preliminary characterization	Performed the experiments	Investigation	YES
6321592	30445768	R.M.	2	performed the mwd characterization	performed the mwd characterization	Performed the experiments	Investigation	YES
6321592	30445768	S.D.	2	performed the maldi-tof experiments	performed the maldi-tof experiments	Performed the experiments	Investigation	YES
3119176	21575155	All authors	2	read, commented on and approved the final manuscript	read, commented on and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
3119176	21575155	IS	2	conceived of the analysis|provided the data	conceived of the analysis	Conceived and designed the experiments	Conceptualization	YES
3119176	21575155	IS	2	conceived of the analysis|provided the data	provided the data	Contributed reagents/materials/analysis tools	Resources	YES
3119176	21575155	LL	2	estimated the parameters	estimated the parameters	Analyzed the data	Formal analysis	YES
3119176	21575155	MF	2	conceived of the analysis|estimated the parameters	conceived of the analysis	Conceived and designed the experiments	Conceptualization	YES
3119176	21575155	MF	2	conceived of the analysis|estimated the parameters	estimated the parameters	Analyzed the data	Formal analysis	YES
3119176	21575155	SR	2	conceived of the analysis|designed the model, performed the analysis, and drafted the manuscript	conceived of the analysis	Conceived and designed the experiments	Conceptualization	YES
3119176	21575155	SR	2	conceived of the analysis|designed the model, performed the analysis, and drafted the manuscript	designed the model, performed the analysis, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
3119176	21575155	WS	2	conceived of the analysis	conceived of the analysis	Conceived and designed the experiments	Conceptualization	YES
3296642	22339759	BS	2	carried out under his guidance and consultation	carried out under his guidance and consultation	Performed the experiments	Investigation|Supervision	YES
3296642	22339759	FA	2	carried out experimental work	carried out experimental work	Performed the experiments	Investigation	YES
5430072	28555143	MR	PLoS52	conceived and designed the experiments|approved the final version of the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5430072	28555143	MR	PLoS52	conceived and designed the experiments|approved the final version of the manuscript	approved the final version of the manuscript	-	-	NO
5430072	28555143	PM	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the results and wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5430072	28555143	PM	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the results and wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5430072	28555143	PM	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the results and wrote the manuscript	analyzed the results and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5430072	28555143	RP	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5430072	28555143	SRK	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
4398327	25874623	GC	CRediT	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Supervision	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398327	25874623	GC	CRediT	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Supervision	Analyzed the data	Analyzed the data	Formal analysis	YES
4398327	25874623	GC	CRediT	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Supervision	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398327	25874623	GC	CRediT	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Supervision	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398327	25874623	GC	CRediT	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Supervision	Supervision	-	Supervision	YES
4398327	25874623	GD	CRediT	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Radioactive data|Mathematical modeling|Supervision	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398327	25874623	GD	CRediT	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Radioactive data|Mathematical modeling|Supervision	Performed the experiments	Performed the experiments	Investigation	YES
4398327	25874623	GD	CRediT	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Radioactive data|Mathematical modeling|Supervision	Analyzed the data	Analyzed the data	Formal analysis	YES
4398327	25874623	GD	CRediT	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Radioactive data|Mathematical modeling|Supervision	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398327	25874623	GD	CRediT	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Radioactive data|Mathematical modeling|Supervision	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398327	25874623	GD	CRediT	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Radioactive data|Mathematical modeling|Supervision	Radioactive data	-	-	NO
4398327	25874623	GD	CRediT	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Radioactive data|Mathematical modeling|Supervision	Mathematical modeling	Performed the experiments	Formal analysis|Methodology	YES
4398327	25874623	GD	CRediT	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Radioactive data|Mathematical modeling|Supervision	Supervision	-	Supervision	YES
4398327	25874623	SS	CRediT	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398327	25874623	SS	CRediT	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398327	25874623	SS	CRediT	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398327	25874623	SS	CRediT	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3305897	22152051	AI	2	has suggested the problem, monitored the progress of the work and finalised the manuscript	has suggested the problem, monitored the progress of the work and finalised the manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
3305897	22152051	SMa	2	carried out most of the experimental work and contributed to the preparation of the manuscript	carried out most of the experimental work and contributed to the preparation of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3305897	22152051	SMar	2	helped characterisation of the compounds prepared	helped characterisation of the compounds prepared	Performed the experiments	Investigation	YES
3305897	22152051	SMu	2	carried out most of the experimental work and contributed to the preparation of the manuscript	carried out most of the experimental work and contributed to the preparation of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3123257	21595957	MD	2	was involved in all discussions of the article and provided extensive comments that were integrated in the final version of the article	was involved in all discussions of the article and provided extensive comments that were integrated in the final version of the article	-	-	NO
5001198	27557119	AM	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5001198	27557119	BK	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5001198	27557119	CG	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5001198	27557119	CM	PLoS52	designed and performed the experiments, analyzed the data, and wrote the paper	designed and performed the experiments, analyzed the data, and wrote the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5001198	27557119	CMK	PLoS52	involved in the whole genome sequencing and analyzed the data	involved in the whole genome sequencing and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5001198	27557119	ENM	PLoS52	performed the phylogenetic analyses	performed the phylogenetic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5001198	27557119	JDL	PLoS52	designed and performed the experiments	designed and performed the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5001198	27557119	JR	PLoS52	conceived and designed the study, coordinated the workflow, and wrote the paper	conceived and designed the study, coordinated the workflow, and wrote the paper	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
5001198	27557119	RGB	PLoS52	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5001198	27557119	RHB	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5001198	27557119	TP	PLoS52	performed maldi analysis	performed maldi analysis	Performed the experiments	Investigation	YES
5001198	27557119	TPLS	PLoS52	sequenced the whole genome and analyzed the data	sequenced the whole genome and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3313904	22185600	AAG	2	participated in design and coordination of the study and edited the manuscript for publication	participated in design and coordination of the study and edited the manuscript for publication	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Review & Editing	YES
3313904	22185600	AVS	2	participated in coordination and design of the study	participated in coordination and design of the study	Conceived and designed the experiments	Methodology|Project administration	YES
3313904	22185600	MVK	2	participated in coordination and design of the study	participated in coordination and design of the study	Conceived and designed the experiments	Methodology|Project administration	YES
3313904	22185600	NUA	2	carried out biological experiments, participated in design of the study, and drafted the manuscript	carried out biological experiments, participated in design of the study, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
6313394	30400643	A.A.I.	2	contributed equally to the actualization of the work	contributed equally to the actualization of the work	-	-	NO
6313394	30400643	A.A.S.	2	contributed equally to the actualization of the work	contributed equally to the actualization of the work	-	-	NO
6313394	30400643	J.I.O.	2	contributed equally to the actualization of the work	contributed equally to the actualization of the work	-	-	NO
4398328	25875735	BWJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398328	25875735	BWJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398328	25875735	BWJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398328	25875735	BWJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398328	25875735	DJH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398328	25875735	DJH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398328	25875735	DJH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398328	25875735	KK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398328	25875735	KK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398328	25875735	KK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398328	25875735	SBP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398328	25875735	SBP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398328	25875735	SBP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398328	25875735	SJK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398328	25875735	SJK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398328	25875735	SJK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398328	25875735	SJK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3123616	21612619	JA	2	wrote the initial draft of the paper, which then underwent revision and final approval by all authors	wrote the initial draft of the paper, which then underwent revision and final approval by all authors	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4393923	25893191	Bill Chang	2	contribute equally to this paper	contribute equally to this paper	-	-	NO
4393923	25893191	Kuo-Wang Tsai	2	contribute equally to this paper|performed most of the experiments	contribute equally to this paper	-	-	NO
4393923	25893191	Kuo-Wang Tsai	2	contribute equally to this paper|performed most of the experiments	performed most of the experiments	Performed the experiments	Investigation	YES
4393923	25893191	Sung-Chou Li	2	supervised this study and wrote this paper	supervised this study and wrote this paper	Wrote the paper	Supervision|Writing - Original Draft	YES
5430074	28555146	AD	PLoS52	curated the experiment and data collection|wrote the manuscript	curated the experiment and data collection	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5430074	28555146	AD	PLoS52	curated the experiment and data collection|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5430074	28555146	All authors	PLoS52	contributed to the development, design, and initial analysis of the experiment	contributed to the development, design, and initial analysis of the experiment	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5430074	28555146	DM	PLoS52	curated the experiment and data collection|wrote the manuscript	curated the experiment and data collection	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5430074	28555146	DM	PLoS52	curated the experiment and data collection|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5430074	28555146	GS	PLoS52	curated the experiment and data collection|wrote the manuscript	curated the experiment and data collection	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5430074	28555146	GS	PLoS52	curated the experiment and data collection|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5430074	28555146	JF	PLoS52	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5430074	28555146	NJ	PLoS52	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5430074	28555146	NW	PLoS52	curated the experiment and data collection|analyzed the data|wrote the manuscript	curated the experiment and data collection	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5430074	28555146	NW	PLoS52	curated the experiment and data collection|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5430074	28555146	NW	PLoS52	curated the experiment and data collection|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5430074	28555146	RM	PLoS52	curated the experiment and data collection|wrote the manuscript	curated the experiment and data collection	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5430074	28555146	RM	PLoS52	curated the experiment and data collection|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5001199	27557137	BL	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5001199	27557137	WZ	PLoS52	conceived and designed the experiments|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5001199	27557137	WZ	PLoS52	conceived and designed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5001199	27557137	XB	PLoS52	performed the experiments|analyzed the data|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5001199	27557137	XB	PLoS52	performed the experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5001199	27557137	XB	PLoS52	performed the experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5001199	27557137	XJ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5001199	27557137	YB	PLoS52	conceived and designed the experiments|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5001199	27557137	YB	PLoS52	conceived and designed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5001199	27557137	ZZ	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
6321593	30304861	A.P.	2	contributed to the writing and editing of the paper	contributed to the writing and editing of the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6321593	30304861	C.V.	2	contributed to the writing and editing of the paper	contributed to the writing and editing of the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6321593	30304861	J.J.S.	2	contributed to the writing and editing of the paper	contributed to the writing and editing of the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6321593	30304861	M.M.	2	contributed to the writing and editing of the paper	contributed to the writing and editing of the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3319420	22244351	HH	2	synthesized the modified oligonucleotides	synthesized the modified oligonucleotides	Performed the experiments	Investigation	YES
3319420	22244351	Jagruti Rana	2	carried out the melting studies	carried out the melting studies	Performed the experiments	Investigation	YES
3319420	22244351	Jyoti Roy	2	carried out the rna cleavage assays	carried out the rna cleavage assays	Performed the experiments	Investigation	YES
3319420	22244351	SP	2	carried out the rna cleavage assays	carried out the rna cleavage assays	Performed the experiments	Investigation	YES
3125306	21663632	AM	2	enrolled patients and collected data on patient history	enrolled patients and collected data on patient history	Performed the experiments	Investigation	YES
3125306	21663632	AP	2	enrolled patients and collected data on patient history	enrolled patients and collected data on patient history	Performed the experiments	Investigation	YES
3125306	21663632	AS	2	participated in the design of the study	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
3125306	21663632	AYD	2	carried out the viral load assays, genotypic drug-resistance test and phylogentic analysis|participated in the design of the study|coordinated the study|drafted the manuscript	carried out the viral load assays, genotypic drug-resistance test and phylogentic analysis	Performed the experiments	Investigation	YES
3125306	21663632	AYD	2	carried out the viral load assays, genotypic drug-resistance test and phylogentic analysis|participated in the design of the study|coordinated the study|drafted the manuscript	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
3125306	21663632	AYD	2	carried out the viral load assays, genotypic drug-resistance test and phylogentic analysis|participated in the design of the study|coordinated the study|drafted the manuscript	coordinated the study	-	Project administration	YES
3125306	21663632	AYD	2	carried out the viral load assays, genotypic drug-resistance test and phylogentic analysis|participated in the design of the study|coordinated the study|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
3125306	21663632	ED	2	participated in the design of the study|drafted the manuscript	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
3125306	21663632	ED	2	participated in the design of the study|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
3125306	21663632	KO	2	enrolled patients and collected data on patient history	enrolled patients and collected data on patient history	Performed the experiments	Investigation	YES
3125306	21663632	MM	2	organized quality assurance for viral load between different sites	organized quality assurance for viral load between different sites	Performed the experiments	Validation	YES
3125306	21663632	MP	2	participated in the design of the study|drafted the manuscript	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
3125306	21663632	MP	2	participated in the design of the study|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
3125306	21663632	MPD	2	participated in the design of the study|coordinated the study	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
3125306	21663632	MPD	2	participated in the design of the study|coordinated the study	coordinated the study	-	Project administration	YES
3125306	21663632	MS	2	enrolled patients and collected data on patient history	enrolled patients and collected data on patient history	Performed the experiments	Investigation	YES
3125306	21663632	NV	2	carried out the viral load assays, genotypic drug-resistance test and phylogentic analysis|drafted the manuscript	carried out the viral load assays, genotypic drug-resistance test and phylogentic analysis	Performed the experiments	Investigation	YES
3125306	21663632	NV	2	carried out the viral load assays, genotypic drug-resistance test and phylogentic analysis|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
3125306	21663632	PP	2	participated in the design of the study|coordinated the study	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
3125306	21663632	PP	2	participated in the design of the study|coordinated the study	coordinated the study	-	Project administration	YES
4398329	25874767	CHW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398329	25874767	LY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398329	25874767	LY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398329	25874767	LY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398329	25874767	LY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398329	25874767	LY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398329	25874767	XDL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398329	25874767	XJL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4398329	25874767	XJL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4398329	25874767	XJL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398329	25874767	XMT	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398329	25874767	YZZ	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
3319428	22269394	MH	2	study paper design develops the forage sampling and the comparative researches, analyses and performs the statistical interpretation of results	study paper design develops the forage sampling and the comparative researches, analyses and performs the statistical interpretation of results	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5001200	27557330	QW	2	jointly designed, implemented, and performed the experiments, and wrote the paper	jointly designed, implemented, and performed the experiments, and wrote the paper	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5001200	27557330	RX	2	jointly designed, implemented, and performed the experiments, and wrote the paper	jointly designed, implemented, and performed the experiments, and wrote the paper	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
6313487	30384469	A.B.	CRediT	Conceptualization|methodology|software|validation|formal analysis|investigation|resources|data curation|writing--original draft preparation|writing--review and editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6313487	30384469	A.B.	CRediT	Conceptualization|methodology|software|validation|formal analysis|investigation|resources|data curation|writing--original draft preparation|writing--review and editing	methodology	Performed the experiments	Methodology	YES
6313487	30384469	A.B.	CRediT	Conceptualization|methodology|software|validation|formal analysis|investigation|resources|data curation|writing--original draft preparation|writing--review and editing	software	Contributed reagents/materials/analysis tools	Software	YES
6313487	30384469	A.B.	CRediT	Conceptualization|methodology|software|validation|formal analysis|investigation|resources|data curation|writing--original draft preparation|writing--review and editing	validation	Performed the experiments	Validation	YES
6313487	30384469	A.B.	CRediT	Conceptualization|methodology|software|validation|formal analysis|investigation|resources|data curation|writing--original draft preparation|writing--review and editing	formal analysis	Analyzed the data	Formal analysis	YES
6313487	30384469	A.B.	CRediT	Conceptualization|methodology|software|validation|formal analysis|investigation|resources|data curation|writing--original draft preparation|writing--review and editing	investigation	Performed the experiments	Investigation	YES
6313487	30384469	A.B.	CRediT	Conceptualization|methodology|software|validation|formal analysis|investigation|resources|data curation|writing--original draft preparation|writing--review and editing	resources	Contributed reagents/materials/analysis tools	Resources	YES
6313487	30384469	A.B.	CRediT	Conceptualization|methodology|software|validation|formal analysis|investigation|resources|data curation|writing--original draft preparation|writing--review and editing	data curation	Analyzed the data	Data curation	YES
6313487	30384469	A.B.	CRediT	Conceptualization|methodology|software|validation|formal analysis|investigation|resources|data curation|writing--original draft preparation|writing--review and editing	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6313487	30384469	A.B.	CRediT	Conceptualization|methodology|software|validation|formal analysis|investigation|resources|data curation|writing--original draft preparation|writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6313487	30384469	A.M.	CRediT	Conceptualization|software|validation|investigation|resources|data curation|writing--original draft preparation|writing--review and editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6313487	30384469	A.M.	CRediT	Conceptualization|software|validation|investigation|resources|data curation|writing--original draft preparation|writing--review and editing	software	Contributed reagents/materials/analysis tools	Software	YES
6313487	30384469	A.M.	CRediT	Conceptualization|software|validation|investigation|resources|data curation|writing--original draft preparation|writing--review and editing	validation	Performed the experiments	Validation	YES
6313487	30384469	A.M.	CRediT	Conceptualization|software|validation|investigation|resources|data curation|writing--original draft preparation|writing--review and editing	investigation	Performed the experiments	Investigation	YES
6313487	30384469	A.M.	CRediT	Conceptualization|software|validation|investigation|resources|data curation|writing--original draft preparation|writing--review and editing	resources	Contributed reagents/materials/analysis tools	Resources	YES
6313487	30384469	A.M.	CRediT	Conceptualization|software|validation|investigation|resources|data curation|writing--original draft preparation|writing--review and editing	data curation	Analyzed the data	Data curation	YES
6313487	30384469	A.M.	CRediT	Conceptualization|software|validation|investigation|resources|data curation|writing--original draft preparation|writing--review and editing	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6313487	30384469	A.M.	CRediT	Conceptualization|software|validation|investigation|resources|data curation|writing--original draft preparation|writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6313487	30384469	J.S.	CRediT	Conceptualization|methodology|software|validation|formal analysis|investigation|resources|data curation|writing--original draft preparation|writing--review and editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6313487	30384469	J.S.	CRediT	Conceptualization|methodology|software|validation|formal analysis|investigation|resources|data curation|writing--original draft preparation|writing--review and editing	methodology	Performed the experiments	Methodology	YES
6313487	30384469	J.S.	CRediT	Conceptualization|methodology|software|validation|formal analysis|investigation|resources|data curation|writing--original draft preparation|writing--review and editing	software	Contributed reagents/materials/analysis tools	Software	YES
6313487	30384469	J.S.	CRediT	Conceptualization|methodology|software|validation|formal analysis|investigation|resources|data curation|writing--original draft preparation|writing--review and editing	validation	Performed the experiments	Validation	YES
6313487	30384469	J.S.	CRediT	Conceptualization|methodology|software|validation|formal analysis|investigation|resources|data curation|writing--original draft preparation|writing--review and editing	formal analysis	Analyzed the data	Formal analysis	YES
6313487	30384469	J.S.	CRediT	Conceptualization|methodology|software|validation|formal analysis|investigation|resources|data curation|writing--original draft preparation|writing--review and editing	investigation	Performed the experiments	Investigation	YES
6313487	30384469	J.S.	CRediT	Conceptualization|methodology|software|validation|formal analysis|investigation|resources|data curation|writing--original draft preparation|writing--review and editing	resources	Contributed reagents/materials/analysis tools	Resources	YES
6313487	30384469	J.S.	CRediT	Conceptualization|methodology|software|validation|formal analysis|investigation|resources|data curation|writing--original draft preparation|writing--review and editing	data curation	Analyzed the data	Data curation	YES
6313487	30384469	J.S.	CRediT	Conceptualization|methodology|software|validation|formal analysis|investigation|resources|data curation|writing--original draft preparation|writing--review and editing	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6313487	30384469	J.S.	CRediT	Conceptualization|methodology|software|validation|formal analysis|investigation|resources|data curation|writing--original draft preparation|writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6313487	30384469	M.S.	CRediT	Conceptualization|software|validation|investigation|resources|data curation|writing--original draft preparation|writing--review and editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6313487	30384469	M.S.	CRediT	Conceptualization|software|validation|investigation|resources|data curation|writing--original draft preparation|writing--review and editing	software	Contributed reagents/materials/analysis tools	Software	YES
6313487	30384469	M.S.	CRediT	Conceptualization|software|validation|investigation|resources|data curation|writing--original draft preparation|writing--review and editing	validation	Performed the experiments	Validation	YES
6313487	30384469	M.S.	CRediT	Conceptualization|software|validation|investigation|resources|data curation|writing--original draft preparation|writing--review and editing	investigation	Performed the experiments	Investigation	YES
6313487	30384469	M.S.	CRediT	Conceptualization|software|validation|investigation|resources|data curation|writing--original draft preparation|writing--review and editing	resources	Contributed reagents/materials/analysis tools	Resources	YES
6313487	30384469	M.S.	CRediT	Conceptualization|software|validation|investigation|resources|data curation|writing--original draft preparation|writing--review and editing	data curation	Analyzed the data	Data curation	YES
6313487	30384469	M.S.	CRediT	Conceptualization|software|validation|investigation|resources|data curation|writing--original draft preparation|writing--review and editing	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6313487	30384469	M.S.	CRediT	Conceptualization|software|validation|investigation|resources|data curation|writing--original draft preparation|writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6313487	30384469	P.A.	CRediT	Conceptualization|methodology|software|validation|formal analysis|investigation|resources|data curation|writing--original draft preparation|writing--review and editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6313487	30384469	P.A.	CRediT	Conceptualization|methodology|software|validation|formal analysis|investigation|resources|data curation|writing--original draft preparation|writing--review and editing	methodology	Performed the experiments	Methodology	YES
6313487	30384469	P.A.	CRediT	Conceptualization|methodology|software|validation|formal analysis|investigation|resources|data curation|writing--original draft preparation|writing--review and editing	software	Contributed reagents/materials/analysis tools	Software	YES
6313487	30384469	P.A.	CRediT	Conceptualization|methodology|software|validation|formal analysis|investigation|resources|data curation|writing--original draft preparation|writing--review and editing	validation	Performed the experiments	Validation	YES
6313487	30384469	P.A.	CRediT	Conceptualization|methodology|software|validation|formal analysis|investigation|resources|data curation|writing--original draft preparation|writing--review and editing	formal analysis	Analyzed the data	Formal analysis	YES
6313487	30384469	P.A.	CRediT	Conceptualization|methodology|software|validation|formal analysis|investigation|resources|data curation|writing--original draft preparation|writing--review and editing	investigation	Performed the experiments	Investigation	YES
6313487	30384469	P.A.	CRediT	Conceptualization|methodology|software|validation|formal analysis|investigation|resources|data curation|writing--original draft preparation|writing--review and editing	resources	Contributed reagents/materials/analysis tools	Resources	YES
6313487	30384469	P.A.	CRediT	Conceptualization|methodology|software|validation|formal analysis|investigation|resources|data curation|writing--original draft preparation|writing--review and editing	data curation	Analyzed the data	Data curation	YES
6313487	30384469	P.A.	CRediT	Conceptualization|methodology|software|validation|formal analysis|investigation|resources|data curation|writing--original draft preparation|writing--review and editing	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6313487	30384469	P.A.	CRediT	Conceptualization|methodology|software|validation|formal analysis|investigation|resources|data curation|writing--original draft preparation|writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6313487	30384469	S.B.	CRediT	Conceptualization|software|validation|investigation|resources|data curation|writing--original draft preparation|writing--review and editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6313487	30384469	S.B.	CRediT	Conceptualization|software|validation|investigation|resources|data curation|writing--original draft preparation|writing--review and editing	software	Contributed reagents/materials/analysis tools	Software	YES
6313487	30384469	S.B.	CRediT	Conceptualization|software|validation|investigation|resources|data curation|writing--original draft preparation|writing--review and editing	validation	Performed the experiments	Validation	YES
6313487	30384469	S.B.	CRediT	Conceptualization|software|validation|investigation|resources|data curation|writing--original draft preparation|writing--review and editing	investigation	Performed the experiments	Investigation	YES
6313487	30384469	S.B.	CRediT	Conceptualization|software|validation|investigation|resources|data curation|writing--original draft preparation|writing--review and editing	resources	Contributed reagents/materials/analysis tools	Resources	YES
6313487	30384469	S.B.	CRediT	Conceptualization|software|validation|investigation|resources|data curation|writing--original draft preparation|writing--review and editing	data curation	Analyzed the data	Data curation	YES
6313487	30384469	S.B.	CRediT	Conceptualization|software|validation|investigation|resources|data curation|writing--original draft preparation|writing--review and editing	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6313487	30384469	S.B.	CRediT	Conceptualization|software|validation|investigation|resources|data curation|writing--original draft preparation|writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6321597	30352986	A.C.	CRediT	Methodology|Writing--review and editing	Methodology	Performed the experiments	Methodology	YES
6321597	30352986	A.C.	CRediT	Methodology|Writing--review and editing	Writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6321597	30352986	C.P.O.	CRediT	Conceptualization|Data curation|Formal analysis|Investigation|Validation|Writing--original draft	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6321597	30352986	C.P.O.	CRediT	Conceptualization|Data curation|Formal analysis|Investigation|Validation|Writing--original draft	Data curation	Analyzed the data	Data curation	YES
6321597	30352986	C.P.O.	CRediT	Conceptualization|Data curation|Formal analysis|Investigation|Validation|Writing--original draft	Formal analysis	Analyzed the data	Formal analysis	YES
6321597	30352986	C.P.O.	CRediT	Conceptualization|Data curation|Formal analysis|Investigation|Validation|Writing--original draft	Investigation	Performed the experiments	Investigation	YES
6321597	30352986	C.P.O.	CRediT	Conceptualization|Data curation|Formal analysis|Investigation|Validation|Writing--original draft	Validation	Performed the experiments	Validation	YES
6321597	30352986	C.P.O.	CRediT	Conceptualization|Data curation|Formal analysis|Investigation|Validation|Writing--original draft	Writing--original draft	Wrote the paper	Writing - Original Draft	YES
6321597	30352986	E.R.	CRediT	Writing--review and editing	Writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6321597	30352986	F.F.F.	CRediT	Validation	Validation	Performed the experiments	Validation	YES
6321597	30352986	G.L.	CRediT	Investigation|Validation	Investigation	Performed the experiments	Investigation	YES
6321597	30352986	G.L.	CRediT	Investigation|Validation	Validation	Performed the experiments	Validation	YES
6321597	30352986	G.T.	CRediT	Conceptualization|Formal analysis|Software|Writing--original draft	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6321597	30352986	G.T.	CRediT	Conceptualization|Formal analysis|Software|Writing--original draft	Formal analysis	Analyzed the data	Formal analysis	YES
6321597	30352986	G.T.	CRediT	Conceptualization|Formal analysis|Software|Writing--original draft	Software	Contributed reagents/materials/analysis tools	Software	YES
6321597	30352986	G.T.	CRediT	Conceptualization|Formal analysis|Software|Writing--original draft	Writing--original draft	Wrote the paper	Writing - Original Draft	YES
6321597	30352986	L.d.G.	CRediT	Conceptualization|Funding acquisition|Methodology|Project administration|Resources|Supervision|Writing--review and editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6321597	30352986	L.d.G.	CRediT	Conceptualization|Funding acquisition|Methodology|Project administration|Resources|Supervision|Writing--review and editing	Funding acquisition	-	Funding acquisition	YES
6321597	30352986	L.d.G.	CRediT	Conceptualization|Funding acquisition|Methodology|Project administration|Resources|Supervision|Writing--review and editing	Methodology	Performed the experiments	Methodology	YES
6321597	30352986	L.d.G.	CRediT	Conceptualization|Funding acquisition|Methodology|Project administration|Resources|Supervision|Writing--review and editing	Project administration	-	Project administration	YES
6321597	30352986	L.d.G.	CRediT	Conceptualization|Funding acquisition|Methodology|Project administration|Resources|Supervision|Writing--review and editing	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6321597	30352986	L.d.G.	CRediT	Conceptualization|Funding acquisition|Methodology|Project administration|Resources|Supervision|Writing--review and editing	Supervision	-	Supervision	YES
6321597	30352986	L.d.G.	CRediT	Conceptualization|Funding acquisition|Methodology|Project administration|Resources|Supervision|Writing--review and editing	Writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6321597	30352986	M.L.T.	CRediT	Funding acquisition|Methodology|Resources|Supervision|Writing--review and editing	Funding acquisition	-	Funding acquisition	YES
6321597	30352986	M.L.T.	CRediT	Funding acquisition|Methodology|Resources|Supervision|Writing--review and editing	Methodology	Performed the experiments	Methodology	YES
6321597	30352986	M.L.T.	CRediT	Funding acquisition|Methodology|Resources|Supervision|Writing--review and editing	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6321597	30352986	M.L.T.	CRediT	Funding acquisition|Methodology|Resources|Supervision|Writing--review and editing	Supervision	-	Supervision	YES
6321597	30352986	M.L.T.	CRediT	Funding acquisition|Methodology|Resources|Supervision|Writing--review and editing	Writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6321597	30352986	M.M.	CRediT	Supervision|Visualization	Supervision	-	Supervision	YES
6321597	30352986	M.M.	CRediT	Supervision|Visualization	Visualization	Analyzed the data	Visualization	YES
6321597	30352986	M.V.	CRediT	Data curation|Formal analysis|Writing--original draft	Data curation	Analyzed the data	Data curation	YES
6321597	30352986	M.V.	CRediT	Data curation|Formal analysis|Writing--original draft	Formal analysis	Analyzed the data	Formal analysis	YES
6321597	30352986	M.V.	CRediT	Data curation|Formal analysis|Writing--original draft	Writing--original draft	Wrote the paper	Writing - Original Draft	YES
6321597	30352986	P.D.L.	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
6321597	30352986	S.P.	CRediT	Data curation|Formal analysis	Data curation	Analyzed the data	Data curation	YES
6321597	30352986	S.P.	CRediT	Data curation|Formal analysis	Formal analysis	Analyzed the data	Formal analysis	YES
5430076	28555153	EH	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5430076	28555153	LZ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5430076	28555153	WS	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5430076	28555153	YK	PLoS52	conceived and designed the experiments|analyzed the data|wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5430076	28555153	YK	PLoS52	conceived and designed the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5430076	28555153	YK	PLoS52	conceived and designed the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5430076	28555153	YX	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5430076	28555153	YX	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
3125307	21663693	BM	2	assisted with the data analysis, assisted in interpretation of the results and provided final approval of the manuscript	assisted with the data analysis, assisted in interpretation of the results and provided final approval of the manuscript	Analyzed the data	Formal analysis	YES
3125307	21663693	CS	2	performed the data analysis, assisted in interpretation of the results and provided final approval of the manuscript	performed the data analysis, assisted in interpretation of the results and provided final approval of the manuscript	Analyzed the data	Formal analysis	YES
3125307	21663693	KWK	2	assisted with the conceptualization and design of the study, interpretation of the data and drafting of the manuscript	assisted with the conceptualization and design of the study, interpretation of the data and drafting of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
3125307	21663693	MG	2	assisted in interpretation of the results and provided final approval of the manuscript	assisted in interpretation of the results and provided final approval of the manuscript	Analyzed the data	Formal analysis	YES
3125307	21663693	SKG	2	conceptualized and designed the study, had primary responsibility for interpretation of the data and drafted the manuscript	conceptualized and designed the study, had primary responsibility for interpretation of the data and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
3125307	21663693	WOO	2	assisted in interpretation of the results and provided final approval of the manuscript	assisted in interpretation of the results and provided final approval of the manuscript	Analyzed the data	Formal analysis	YES
4398330	25875766	AAR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398330	25875766	AAR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398330	25875766	AAR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398330	25875766	AAR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398330	25875766	JDM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398330	25875766	JJ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398330	25875766	JR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398330	25875766	JR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398330	25875766	JR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398330	25875766	SB	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398330	25875766	SB	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398330	25875766	VN	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
3325881	22424056	MK	2	provided the cell line, some technical facilities, and participated in the manuscript preparation	provided the cell line, some technical facilities, and participated in the manuscript preparation	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Resources|Writing - Original Draft	YES
3325881	22424056	SAL	2	participated in the study design, performed all experiments, and prepared the draft versions of the manuscript	participated in the study design, performed all experiments, and prepared the draft versions of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
3325881	22424056	SISR	2	proposed the subject, supervised the study, participated in the study design, and in the manuscript preparation	proposed the subject, supervised the study, participated in the study design, and in the manuscript preparation	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Supervision|Writing - Original Draft	YES
5430159	28555148	All the authors	2	have revised the final draft of the manuscript	have revised the final draft of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5430159	28555148	GA	2	conceived and designed the experiment	conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5430159	28555148	GC	2	conceived and designed the experiment	conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5430159	28555148	MD	2	maintained plant materials and has done the nutritional analysis and wet lab validation	maintained plant materials and has done the nutritional analysis and wet lab validation	Performed the experiments	Investigation|Validation	YES
4398348	25875003	DL	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398348	25875003	DL	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398348	25875003	DL	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398348	25875003	DL	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398348	25875003	JL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398348	25875003	JW	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4398348	25875003	JW	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398348	25875003	JX	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398348	25875003	JX	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398348	25875003	JX	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398348	25875003	JX	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398348	25875003	YY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398348	25875003	YY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398348	25875003	YY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398348	25875003	YY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398348	25875003	YY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6321619	30282960	A.-H.L.	2	wrote the manuscript|participated in planning and performing the experiments|made substantial contributions to the conception and design of the research, data collection, and the editing of the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6321619	30282960	A.-H.L.	2	wrote the manuscript|participated in planning and performing the experiments|made substantial contributions to the conception and design of the research, data collection, and the editing of the manuscript	participated in planning and performing the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6321619	30282960	A.-H.L.	2	wrote the manuscript|participated in planning and performing the experiments|made substantial contributions to the conception and design of the research, data collection, and the editing of the manuscript	made substantial contributions to the conception and design of the research, data collection, and the editing of the manuscript	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Investigation|Methodology|Resources|Writing - Review & Editing	YES
6321619	30282960	All authors	2	reviewed the manuscript and approved its final version	reviewed the manuscript and approved its final version	Wrote the paper	Writing - Review & Editing	YES
6321619	30282960	B.-Y.C.	2	participated in data analysis and interpretation	participated in data analysis and interpretation	Analyzed the data	Formal analysis	YES
6321619	30282960	C.-H.W.	2	participated in planning and performing the experiments	participated in planning and performing the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6321619	30282960	C.-P.C.	2	participated in planning and performing the experiments|participated in data analysis and interpretation|made substantial contributions to the conception and design of the research, data collection, and the editing of the manuscript	participated in planning and performing the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6321619	30282960	C.-P.C.	2	participated in planning and performing the experiments|participated in data analysis and interpretation|made substantial contributions to the conception and design of the research, data collection, and the editing of the manuscript	participated in data analysis and interpretation	Analyzed the data	Formal analysis	YES
6321619	30282960	C.-P.C.	2	participated in planning and performing the experiments|participated in data analysis and interpretation|made substantial contributions to the conception and design of the research, data collection, and the editing of the manuscript	made substantial contributions to the conception and design of the research, data collection, and the editing of the manuscript	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Investigation|Methodology|Resources|Writing - Review & Editing	YES
6321619	30282960	H.-C.C.	2	participated in planning and performing the experiments|made substantial contributions to the conception and design of the research, data collection, and the editing of the manuscript	participated in planning and performing the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6321619	30282960	H.-C.C.	2	participated in planning and performing the experiments|made substantial contributions to the conception and design of the research, data collection, and the editing of the manuscript	made substantial contributions to the conception and design of the research, data collection, and the editing of the manuscript	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Investigation|Methodology|Resources|Writing - Review & Editing	YES
6321619	30282960	H.-W.G.	2	participated in data analysis and interpretation	participated in data analysis and interpretation	Analyzed the data	Formal analysis	YES
6321619	30282960	W.-C.K.	2	participated in planning and performing the experiments	participated in planning and performing the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3126756	21609449	All authors	2	actively participated in the analysis and interpretation of the data and critical revision of the draft article	actively participated in the analysis and interpretation of the data and critical revision of the draft article	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
3126756	21609449	CAD	2	originally conceived of and designed the analysis and drafted the article	originally conceived of and designed the analysis and drafted the article	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
3126756	21609449	CAN	2	originally conceived of and designed the analysis and drafted the article|contributed to the collection and assembly of the data	originally conceived of and designed the analysis and drafted the article	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
3126756	21609449	CAN	2	originally conceived of and designed the analysis and drafted the article|contributed to the collection and assembly of the data	contributed to the collection and assembly of the data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
3126756	21609449	EM	2	contributed to the collection and assembly of the data	contributed to the collection and assembly of the data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
3126756	21609449	JMGC	2	originally conceived of and designed the analysis and drafted the article	originally conceived of and designed the analysis and drafted the article	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
3126756	21609449	PM	2	contributed to the collection and assembly of the data	contributed to the collection and assembly of the data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
3126756	21609449	SG	2	originally conceived of and designed the analysis and drafted the article|contributed to the collection and assembly of the data	originally conceived of and designed the analysis and drafted the article	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
3126756	21609449	SG	2	originally conceived of and designed the analysis and drafted the article|contributed to the collection and assembly of the data	contributed to the collection and assembly of the data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5001201	27556637	All authors	2	wrote and approve the manuscript	wrote and approve the manuscript	Wrote the paper	Writing - Original Draft	YES
5001201	27556637	MM	2	analysed the networks and biological significance	analysed the networks and biological significance	-	-	NO
5001201	27556637	NC	2	generated the idea and supervised the whole project	generated the idea and supervised the whole project	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Supervision	YES
5001201	27556637	NS	2	developed and implemented the algorithm	developed and implemented the algorithm	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
3334710	22248151	CM	2	contributed to the color analysis, performed statistical analyses and helped to interpretation of data	contributed to the color analysis, performed statistical analyses and helped to interpretation of data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
3334710	22248151	EA	2	contributed to jam processing, performed extractions	contributed to jam processing, performed extractions	Performed the experiments	Investigation	YES
3334710	22248151	FRAP	2	color analysis, results interpretation and manuscript preparation	color analysis, results interpretation and manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3334710	22248151	MAP	2	conceived the research design, performed jam processing	conceived the research design, performed jam processing	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
3334710	22248151	TMA	2	color analysis, results interpretation and manuscript preparation	color analysis, results interpretation and manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3334710	22248151	TP	2	l-asac analysis	l-asac analysis	-	-	NO
3127801	21658260	All authors	2	were involved in the write-up and approved the final submission of the article and its contents	were involved in the write-up and approved the final submission of the article and its contents	Wrote the paper	Writing - Original Draft	YES
3127801	21658260	CC	2	supervised the data collection and analysis	supervised the data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Supervision	YES
3127801	21658260	CN	2	managed and conducted the fieldwork	managed and conducted the fieldwork	Performed the experiments	Investigation	YES
3127801	21658260	MS	2	managed the data set, conducted the data analysis, and wrote the first draft of the article	managed the data set, conducted the data analysis, and wrote the first draft of the article	Analyzed the data|Wrote the paper	Data curation|Formal analysis|Writing - Original Draft	YES
3127801	21658260	Manicaland Project	2	which hosted this research	which hosted this research	-	-	NO
6313508	30262779	C.F.	CRediT7	data curation	data curation	Analyzed the data	Data curation	YES
6313508	30262779	G.L.R.	CRediT7	formal analysis	formal analysis	Analyzed the data	Formal analysis	YES
6313508	30262779	M.F.	CRediT7	supervision and writing-review	supervision and writing-review	Wrote the paper	Supervision|Writing - Review & Editing	YES
6313508	30262779	M.T.	CRediT7	writing-original draft and methodology	writing-original draft and methodology	Performed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4398350	25875758	AF	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398350	25875758	AF	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398350	25875758	DEO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398350	25875758	DEO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398350	25875758	DEO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398350	25875758	DEO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398350	25875758	DEO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398350	25875758	JDEG	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398350	25875758	JDEG	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398350	25875758	KK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398350	25875758	KK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398350	25875758	KK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398350	25875758	KK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398350	25875758	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398350	25875758	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398350	25875758	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398350	25875758	REM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398350	25875758	REM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398350	25875758	REM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398350	25875758	RS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398350	25875758	RS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398350	25875758	ZMS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398350	25875758	ZMS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398350	25875758	ZMS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398350	25875758	ZMS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398350	25875758	ZMS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3133533	21689437	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
3133533	21689437	JDS	2	collaborated equally in writing the article	collaborated equally in writing the article	Wrote the paper	Writing - Original Draft	YES
3133533	21689437	TLM	2	collaborated equally in writing the article	collaborated equally in writing the article	Wrote the paper	Writing - Original Draft	YES
5430163	28555149	FW	PLoS52	performed the colletotrichum gloeosporioides culture, infection and rna isolation and quality assessment|analyzed the data|drafted the manuscript	performed the colletotrichum gloeosporioides culture, infection and rna isolation and quality assessment	Performed the experiments	Investigation|Validation	YES
5430163	28555149	FW	PLoS52	performed the colletotrichum gloeosporioides culture, infection and rna isolation and quality assessment|analyzed the data|drafted the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5430163	28555149	FW	PLoS52	performed the colletotrichum gloeosporioides culture, infection and rna isolation and quality assessment|analyzed the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5430163	28555149	FZ	PLoS52	performed qrt-pcr measurements|analyzed the data|drafted the manuscript	performed qrt-pcr measurements	Performed the experiments	Investigation	YES
5430163	28555149	FZ	PLoS52	performed qrt-pcr measurements|analyzed the data|drafted the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5430163	28555149	FZ	PLoS52	performed qrt-pcr measurements|analyzed the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5430163	28555149	JF	PLoS52	planned and organized the study	planned and organized the study	Conceived and designed the experiments	Conceptualization|Project administration	YES
5430163	28555149	MC	PLoS52	performed the colletotrichum gloeosporioides culture, infection and rna isolation and quality assessment|drafted the manuscript	performed the colletotrichum gloeosporioides culture, infection and rna isolation and quality assessment	Performed the experiments	Investigation|Validation	YES
5430163	28555149	MC	PLoS52	performed the colletotrichum gloeosporioides culture, infection and rna isolation and quality assessment|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5430163	28555149	YM	PLoS52	planned and organized the study|analyzed the data|drafted the manuscript	planned and organized the study	Conceived and designed the experiments	Conceptualization|Project administration	YES
5430163	28555149	YM	PLoS52	planned and organized the study|analyzed the data|drafted the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5430163	28555149	YM	PLoS52	planned and organized the study|analyzed the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5430163	28555149	ZL	PLoS52	planned and organized the study	planned and organized the study	Conceived and designed the experiments	Conceptualization|Project administration	YES
5430163	28555149	ZZ	PLoS52	provided the plant material	provided the plant material	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
3337232	22429523	DSS	2	contributed equally to the study design, collection of data, development of the animals and vegetables sampling, analyses, interpretation of results and preparation of the paper	contributed equally to the study design, collection of data, development of the animals and vegetables sampling, analyses, interpretation of results and preparation of the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
3337232	22429523	IG	2	contributed equally to the study design, collection of data, development of the animals and vegetables sampling, analyses, interpretation of results and preparation of the paper	contributed equally to the study design, collection of data, development of the animals and vegetables sampling, analyses, interpretation of results and preparation of the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
3136398	21718524	All authors	2	participated in the design of the study and development of the questionnaires	participated in the design of the study and development of the questionnaires	Conceived and designed the experiments	Methodology	YES
3136398	21718524	FM	2	conducted the data analysis	conducted the data analysis	Analyzed the data	Formal analysis	YES
3136398	21718524	LA	2	conducted the data analysis	conducted the data analysis	Analyzed the data	Formal analysis	YES
3136398	21718524	NMT	2	conducted the data analysis	conducted the data analysis	Analyzed the data	Formal analysis	YES
3136398	21718524	RW	2	conducted the data analysis	conducted the data analysis	Analyzed the data	Formal analysis	YES
3136398	21718524	SN	2	conducted the data analysis	conducted the data analysis	Analyzed the data	Formal analysis	YES
4398351	25875961	ABFCP	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398351	25875961	ACCA	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4398351	25875961	ATC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398351	25875961	ATC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398351	25875961	ATC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398351	25875961	ATC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398351	25875961	CRCF	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4398351	25875961	CRCF	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4398351	25875961	DMVA	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4398351	25875961	DMVA	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4398351	25875961	ECS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398351	25875961	EML	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398351	25875961	FFA	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398351	25875961	FFA	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398351	25875961	FMFC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398351	25875961	FMFC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398351	25875961	FMFC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398351	25875961	MCA	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398351	25875961	MSSA	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398351	25875961	OAMF	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398351	25875961	OAMF	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398351	25875961	RDR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398351	25875961	RDR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4398351	25875961	RDR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4398351	25875961	RGC	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4398351	25875961	RGC	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4398351	25875961	SMES	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398351	25875961	SMES	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398351	25875961	SMG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398351	25875961	SMG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398351	25875961	SMG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398351	25875961	SMG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6321636	30558378	C.M.L.	CRediT	Methodology|Validation|Data curation	Methodology	Performed the experiments	Methodology	YES
6321636	30558378	C.M.L.	CRediT	Methodology|Validation|Data curation	Validation	Performed the experiments	Validation	YES
6321636	30558378	C.M.L.	CRediT	Methodology|Validation|Data curation	Data curation	Analyzed the data	Data curation	YES
6321636	30558378	E.F.	CRediT	Methodology|Validation|Data curation	Methodology	Performed the experiments	Methodology	YES
6321636	30558378	E.F.	CRediT	Methodology|Validation|Data curation	Validation	Performed the experiments	Validation	YES
6321636	30558378	E.F.	CRediT	Methodology|Validation|Data curation	Data curation	Analyzed the data	Data curation	YES
6321636	30558378	M.E.C.D.R.O.	CRediT	Funding acquisition	Funding acquisition	-	Funding acquisition	YES
6321636	30558378	M.L.	CRediT	Conceptualization|Methodology|Validation|Formal analysis|Data curation|Writing--original draft preparation|Writing--review & editing|Visualization|Supervision|Project administration|Funding acquisition	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6321636	30558378	M.L.	CRediT	Conceptualization|Methodology|Validation|Formal analysis|Data curation|Writing--original draft preparation|Writing--review & editing|Visualization|Supervision|Project administration|Funding acquisition	Methodology	Performed the experiments	Methodology	YES
6321636	30558378	M.L.	CRediT	Conceptualization|Methodology|Validation|Formal analysis|Data curation|Writing--original draft preparation|Writing--review & editing|Visualization|Supervision|Project administration|Funding acquisition	Validation	Performed the experiments	Validation	YES
6321636	30558378	M.L.	CRediT	Conceptualization|Methodology|Validation|Formal analysis|Data curation|Writing--original draft preparation|Writing--review & editing|Visualization|Supervision|Project administration|Funding acquisition	Formal analysis	Analyzed the data	Formal analysis	YES
6321636	30558378	M.L.	CRediT	Conceptualization|Methodology|Validation|Formal analysis|Data curation|Writing--original draft preparation|Writing--review & editing|Visualization|Supervision|Project administration|Funding acquisition	Data curation	Analyzed the data	Data curation	YES
6321636	30558378	M.L.	CRediT	Conceptualization|Methodology|Validation|Formal analysis|Data curation|Writing--original draft preparation|Writing--review & editing|Visualization|Supervision|Project administration|Funding acquisition	Writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6321636	30558378	M.L.	CRediT	Conceptualization|Methodology|Validation|Formal analysis|Data curation|Writing--original draft preparation|Writing--review & editing|Visualization|Supervision|Project administration|Funding acquisition	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6321636	30558378	M.L.	CRediT	Conceptualization|Methodology|Validation|Formal analysis|Data curation|Writing--original draft preparation|Writing--review & editing|Visualization|Supervision|Project administration|Funding acquisition	Visualization	Analyzed the data	Visualization	YES
6321636	30558378	M.L.	CRediT	Conceptualization|Methodology|Validation|Formal analysis|Data curation|Writing--original draft preparation|Writing--review & editing|Visualization|Supervision|Project administration|Funding acquisition	Supervision	-	Supervision	YES
6321636	30558378	M.L.	CRediT	Conceptualization|Methodology|Validation|Formal analysis|Data curation|Writing--original draft preparation|Writing--review & editing|Visualization|Supervision|Project administration|Funding acquisition	Project administration	-	Project administration	YES
6321636	30558378	M.L.	CRediT	Conceptualization|Methodology|Validation|Formal analysis|Data curation|Writing--original draft preparation|Writing--review & editing|Visualization|Supervision|Project administration|Funding acquisition	Funding acquisition	-	Funding acquisition	YES
6321636	30558378	T.V.	CRediT	Methodology|Validation|Data curation|Writing--review & editing	Methodology	Performed the experiments	Methodology	YES
6321636	30558378	T.V.	CRediT	Methodology|Validation|Data curation|Writing--review & editing	Validation	Performed the experiments	Validation	YES
6321636	30558378	T.V.	CRediT	Methodology|Validation|Data curation|Writing--review & editing	Data curation	Analyzed the data	Data curation	YES
6321636	30558378	T.V.	CRediT	Methodology|Validation|Data curation|Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
3338092	22436305	MMNZ	2	carried out the experiment and drafted the manuscript	carried out the experiment and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3338092	22436305	YTL	2	prepared the manuscript for submission and coordinated final formulation	prepared the manuscript for submission and coordinated final formulation	Conceived and designed the experiments|Wrote the paper	Conceptualization|Project administration|Writing - Original Draft	YES
3338092	22436305	ZD	2	formulated the research idea and prepared the manuscript draft version	formulated the research idea and prepared the manuscript draft version	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4398352	25876105	BY	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4398352	25876105	BY	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398352	25876105	CG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398352	25876105	DJ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398352	25876105	DJ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398352	25876105	DJ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398352	25876105	JM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398352	25876105	JW	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398352	25876105	JW	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398352	25876105	MT	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398352	25876105	ND	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398352	25876105	ND	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398352	25876105	WH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5432532	28559899	CP	2	planned and designed the research|analyzed and interpreted the data and wrote the manuscript	planned and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5432532	28559899	CP	2	planned and designed the research|analyzed and interpreted the data and wrote the manuscript	analyzed and interpreted the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5432532	28559899	IV-V	2	contributed to data analysis and improved the manuscript	contributed to data analysis and improved the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5432532	28559899	RS	2	provided hormone analysis	provided hormone analysis	-	-	NO
5432532	28559899	SVW	2	planned and designed the research|analyzed and interpreted the data and wrote the manuscript	planned and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5432532	28559899	SVW	2	planned and designed the research|analyzed and interpreted the data and wrote the manuscript	analyzed and interpreted the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5432532	28559899	YZ	2	planned and designed the research|conducted the laboratory work|analyzed and interpreted the data and wrote the manuscript	planned and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5432532	28559899	YZ	2	planned and designed the research|conducted the laboratory work|analyzed and interpreted the data and wrote the manuscript	conducted the laboratory work	Performed the experiments	Investigation	YES
5432532	28559899	YZ	2	planned and designed the research|conducted the laboratory work|analyzed and interpreted the data and wrote the manuscript	analyzed and interpreted the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3338369	22264235	RS	7	Involved in the useful discussion and participated in designing experiment	Involved in the useful discussion and participated in designing experiment	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3338369	22264235	SGM	7	Participated in the experimental designing and method optimization	Participated in the experimental designing and method optimization	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3338369	22264235	UF	7	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5001203	27556923	All authors	2	contribute to the manuscript	contribute to the manuscript	-	-	NO
5001203	27556923	DW	2	conceived and designed the study|contributed to the initial design of the algorithm|contributed mbdcap-seq datasets for prostate samples	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5001203	27556923	DW	2	conceived and designed the study|contributed to the initial design of the algorithm|contributed mbdcap-seq datasets for prostate samples	contributed to the initial design of the algorithm	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
5001203	27556923	DW	2	conceived and designed the study|contributed to the initial design of the algorithm|contributed mbdcap-seq datasets for prostate samples	contributed mbdcap-seq datasets for prostate samples	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5001203	27556923	RL	2	conceived and designed the study|contributed mbdcap-seq datasets for prostate samples	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5001203	27556923	RL	2	conceived and designed the study|contributed mbdcap-seq datasets for prostate samples	contributed mbdcap-seq datasets for prostate samples	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5001203	27556923	YC	2	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5001203	27556923	YL	2	conceived and designed the study|contributed to the initial design of the algorithm|implemented the algorithm carried out the simulation procedure	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5001203	27556923	YL	2	conceived and designed the study|contributed to the initial design of the algorithm|implemented the algorithm carried out the simulation procedure	contributed to the initial design of the algorithm	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
5001203	27556923	YL	2	conceived and designed the study|contributed to the initial design of the algorithm|implemented the algorithm carried out the simulation procedure	implemented the algorithm carried out the simulation procedure	Performed the experiments|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Software	YES
3143073	21679416	AJA	2	helped in acquisition of data, participated in critical data organization, cleaning and preliminary analysis, and helped to draft the manuscript	helped in acquisition of data, participated in critical data organization, cleaning and preliminary analysis, and helped to draft the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Formal analysis|Investigation|Writing - Original Draft	YES
3143073	21679416	JJM	2	conceived and designed the study, drafted the manuscript, and participated in data analysis and interpretation	conceived and designed the study, drafted the manuscript, and participated in data analysis and interpretation	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
3143073	21679416	JTB	2	helped to draft the manuscript, revising it critically for important intellectual content, and participated in statistical analysis and interpretation	helped to draft the manuscript, revising it critically for important intellectual content, and participated in statistical analysis and interpretation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
3143073	21679416	PJW	2	helped to conceive and design the study, helped to draft the manuscript, revising it critically for important intellectual content, and participated in statistical analysis and interpretation	helped to conceive and design the study, helped to draft the manuscript, revising it critically for important intellectual content, and participated in statistical analysis and interpretation	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
3143073	21679416	PLR	2	provided significant input in conceiving and designing the study, participated in drafting the manuscript, revising it critically for important intellectual content, and participated in data analysis and interpretation	provided significant input in conceiving and designing the study, participated in drafting the manuscript, revising it critically for important intellectual content, and participated in data analysis and interpretation	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
3143073	21679416	SP	2	participated in drafting the manuscript and performed statistical analysis	participated in drafting the manuscript and performed statistical analysis	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3143073	21679416	TNK	2	helped to conceive and design the study, and to draft the manuscript, revising it critically for important intellectual content	helped to conceive and design the study, and to draft the manuscript, revising it critically for important intellectual content	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
3143073	21679416	WA	2	participated in the design of the study, performed acquisition of data, and helped to draft the manuscript	participated in the design of the study, performed acquisition of data, and helped to draft the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
6313542	30373250	B.O.-G.	2	contributed to the analysis of the data and the writing of the paper	contributed to the analysis of the data and the writing of the paper	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
6313542	30373250	E.O.-G.	2	conceived the idea for this article, wrote it, and performed the analysis	conceived the idea for this article, wrote it, and performed the analysis	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
4398353	25875631	HJY	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4398353	25875631	KKK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398353	25875631	KKK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398353	25875631	KKK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398353	25875631	KOC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4398353	25875631	KOC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398353	25875631	PNK	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398353	25875631	PNK	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398353	25875631	PNK	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398353	25875631	SL	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398353	25875631	SL	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398353	25875631	SL	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398353	25875631	YDJ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398353	25875631	YDJ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398353	25875631	YDJ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398353	25875631	YEJ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398353	25875631	YX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398353	25875631	YX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398353	25875631	YX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398353	25875631	YX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398353	25875631	YX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5432542	28559901	All authors	2	participated the discussion of experiment design	participated the discussion of experiment design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5432542	28559901	BA	2	also read and improved the final manuscript	also read and improved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5432542	28559901	FB	2	made very significant revisions	made very significant revisions	Wrote the paper	Writing - Review & Editing	YES
3344677	22475262	EAA	2	carried out all the experimental work, designed the proposed methods and analyzed the data statistically together	carried out all the experimental work, designed the proposed methods and analyzed the data statistically together	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation|Methodology	YES
3344677	22475262	NSA	2	carried out all the experimental work, designed the proposed methods and analyzed the data statistically together	carried out all the experimental work, designed the proposed methods and analyzed the data statistically together	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation|Methodology	YES
4398354	25875609	AMS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398354	25875609	BMB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398354	25875609	BMB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4398354	25875609	BMB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4398354	25875609	BS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398354	25875609	CL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398354	25875609	FS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398354	25875609	HHS	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398354	25875609	HS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398354	25875609	HS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4398354	25875609	HS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4398354	25875609	HS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4398354	25875609	MN	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398354	25875609	SG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398354	25875609	SOB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398354	25875609	TM	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4398354	25875609	TM	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4398354	25875609	TWB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398354	25875609	TWB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398354	25875609	TWB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398354	25875609	TWB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398354	25875609	WB	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5001204	27557147	CZX	2	contributed to the computational analyses	contributed to the computational analyses	Analyzed the data	Formal analysis	YES
5001204	27557147	HL	2	conceived and directed the project, arranged the sampling, provided advice on analysis, and contributed to writing of the manuscript	conceived and directed the project, arranged the sampling, provided advice on analysis, and contributed to writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Supervision|Writing - Original Draft	YES
5001204	27557147	JL	2	developed the programs and workflows, analysed the data, and wrote the manuscript	developed the programs and workflows, analysed the data, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Software|Writing - Original Draft	YES
5001204	27557147	LW	2	contributed to the data analysis	contributed to the data analysis	Analyzed the data	Formal analysis	YES
5001204	27557147	TCS	2	was responsible for sample collection and processing for analysis	was responsible for sample collection and processing for analysis	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5001204	27557147	WC	2	provided some advice on analysis and contributed partly to writing of the manuscript	provided some advice on analysis and contributed partly to writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5001204	27557147	WXF	2	contributed to the computational analyses	contributed to the computational analyses	Analyzed the data	Formal analysis	YES
5001204	27557147	WY	2	developed the programs and workflows, analysed the data, and wrote the manuscript	developed the programs and workflows, analysed the data, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Software|Writing - Original Draft	YES
5001204	27557147	XFD	2	contributed to the data analysis	contributed to the data analysis	Analyzed the data	Formal analysis	YES
5001204	27557147	YLD	2	was responsible for sample collection and processing for analysis	was responsible for sample collection and processing for analysis	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5001204	27557147	YLL	2	conceived and directed the project, arranged the sampling, provided advice on analysis, and contributed to writing of the manuscript	conceived and directed the project, arranged the sampling, provided advice on analysis, and contributed to writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Supervision|Writing - Original Draft	YES
5001204	27557147	YW	2	contributed to the data analysis	contributed to the data analysis	Analyzed the data	Formal analysis	YES
3146892	21726457	AW	2	participated in study design and coordination, and helped revise the manuscript for intellectual content	participated in study design and coordination, and helped revise the manuscript for intellectual content	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Review & Editing	YES
3146892	21726457	BK	2	carried out data collection activities, participated in the analysis and interpretation of the data, and helped draft the manuscript	carried out data collection activities, participated in the analysis and interpretation of the data, and helped draft the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3146892	21726457	CB	2	participated in study design and coordination, and helped revise the manuscript for intellectual content	participated in study design and coordination, and helped revise the manuscript for intellectual content	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Review & Editing	YES
3146892	21726457	DA	2	carried out data collection activities, participated in the analysis and interpretation of the data, and helped draft the manuscript	carried out data collection activities, participated in the analysis and interpretation of the data, and helped draft the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3146892	21726457	JL	2	carried out data collection activities, participated in the analysis and interpretation of the data, and helped draft the manuscript	carried out data collection activities, participated in the analysis and interpretation of the data, and helped draft the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3146892	21726457	PL	2	participated in study design and coordination, and helped revise the manuscript for intellectual content	participated in study design and coordination, and helped revise the manuscript for intellectual content	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Review & Editing	YES
3146892	21726457	RT	2	participated in study design and coordination, and helped revise the manuscript for intellectual content	participated in study design and coordination, and helped revise the manuscript for intellectual content	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Review & Editing	YES
3146892	21726457	SB	2	participated in the design and coordination of the study, participated in data analysis, and helped draft the manuscript	participated in the design and coordination of the study, participated in data analysis, and helped draft the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Project administration|Writing - Original Draft	YES
4395993	25918725	Andrea Glutz	2	equally contributed to this study and are considered first authors	equally contributed to this study and are considered first authors	-	-	NO
4395993	25918725	Katharina Leitmeyer	2	equally contributed to this study and are considered first authors	equally contributed to this study and are considered first authors	-	-	NO
6358724	30669330	M.T.H.	CRediT	Conceptualization|methodology|validation|formal analysis|investigation|data curation|writing--original draft preparation|writing--review and editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6358724	30669330	M.T.H.	CRediT	Conceptualization|methodology|validation|formal analysis|investigation|data curation|writing--original draft preparation|writing--review and editing	methodology	Performed the experiments	Methodology	YES
6358724	30669330	M.T.H.	CRediT	Conceptualization|methodology|validation|formal analysis|investigation|data curation|writing--original draft preparation|writing--review and editing	validation	Performed the experiments	Validation	YES
6358724	30669330	M.T.H.	CRediT	Conceptualization|methodology|validation|formal analysis|investigation|data curation|writing--original draft preparation|writing--review and editing	formal analysis	Analyzed the data	Formal analysis	YES
6358724	30669330	M.T.H.	CRediT	Conceptualization|methodology|validation|formal analysis|investigation|data curation|writing--original draft preparation|writing--review and editing	investigation	Performed the experiments	Investigation	YES
6358724	30669330	M.T.H.	CRediT	Conceptualization|methodology|validation|formal analysis|investigation|data curation|writing--original draft preparation|writing--review and editing	data curation	Analyzed the data	Data curation	YES
6358724	30669330	M.T.H.	CRediT	Conceptualization|methodology|validation|formal analysis|investigation|data curation|writing--original draft preparation|writing--review and editing	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6358724	30669330	M.T.H.	CRediT	Conceptualization|methodology|validation|formal analysis|investigation|data curation|writing--original draft preparation|writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6358724	30669330	N.F.	CRediT	Conceptualization|methodology|validation|formal analysis|investigation|data curation|writing--original draft preparation|writing--review and editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6358724	30669330	N.F.	CRediT	Conceptualization|methodology|validation|formal analysis|investigation|data curation|writing--original draft preparation|writing--review and editing	methodology	Performed the experiments	Methodology	YES
6358724	30669330	N.F.	CRediT	Conceptualization|methodology|validation|formal analysis|investigation|data curation|writing--original draft preparation|writing--review and editing	validation	Performed the experiments	Validation	YES
6358724	30669330	N.F.	CRediT	Conceptualization|methodology|validation|formal analysis|investigation|data curation|writing--original draft preparation|writing--review and editing	formal analysis	Analyzed the data	Formal analysis	YES
6358724	30669330	N.F.	CRediT	Conceptualization|methodology|validation|formal analysis|investigation|data curation|writing--original draft preparation|writing--review and editing	investigation	Performed the experiments	Investigation	YES
6358724	30669330	N.F.	CRediT	Conceptualization|methodology|validation|formal analysis|investigation|data curation|writing--original draft preparation|writing--review and editing	data curation	Analyzed the data	Data curation	YES
6358724	30669330	N.F.	CRediT	Conceptualization|methodology|validation|formal analysis|investigation|data curation|writing--original draft preparation|writing--review and editing	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6358724	30669330	N.F.	CRediT	Conceptualization|methodology|validation|formal analysis|investigation|data curation|writing--original draft preparation|writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6358724	30669330	Y.P.	CRediT	Conceptualization|methodology|validation|formal analysis|resources|writing--review and editing|supervision|project administration	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6358724	30669330	Y.P.	CRediT	Conceptualization|methodology|validation|formal analysis|resources|writing--review and editing|supervision|project administration	methodology	Performed the experiments	Methodology	YES
6358724	30669330	Y.P.	CRediT	Conceptualization|methodology|validation|formal analysis|resources|writing--review and editing|supervision|project administration	validation	Performed the experiments	Validation	YES
6358724	30669330	Y.P.	CRediT	Conceptualization|methodology|validation|formal analysis|resources|writing--review and editing|supervision|project administration	formal analysis	Analyzed the data	Formal analysis	YES
6358724	30669330	Y.P.	CRediT	Conceptualization|methodology|validation|formal analysis|resources|writing--review and editing|supervision|project administration	resources	Contributed reagents/materials/analysis tools	Resources	YES
6358724	30669330	Y.P.	CRediT	Conceptualization|methodology|validation|formal analysis|resources|writing--review and editing|supervision|project administration	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6358724	30669330	Y.P.	CRediT	Conceptualization|methodology|validation|formal analysis|resources|writing--review and editing|supervision|project administration	supervision	-	Supervision	YES
6358724	30669330	Y.P.	CRediT	Conceptualization|methodology|validation|formal analysis|resources|writing--review and editing|supervision|project administration	project administration	-	Project administration	YES
6313579	30469323	DOPS	2	adjuvants and revising the manuscript	adjuvants and revising the manuscript	Wrote the paper	Writing - Review & Editing	YES
6313579	30469323	G.C.-M.	2	contributed in writing and revision of the paper	contributed in writing and revision of the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3348029	22439648	CMG	2	reviewed the literature on carboxylic acids and how their indoor concentration might be estimated	reviewed the literature on carboxylic acids and how their indoor concentration might be estimated	Analyzed the data	Formal analysis	YES
5432546	28559908	HL	2	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5432546	28559908	XS	2	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5432546	28559908	XW	2	conducted gene sequence and wrote the manuscript|analyzed data	conducted gene sequence and wrote the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5432546	28559908	XW	2	conducted gene sequence and wrote the manuscript|analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5432546	28559908	XX	2	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5432546	28559908	XZ	2	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5432546	28559908	YJ	2	designed the experiments and led analyzing data and writing of the manuscript	designed the experiments and led analyzing data and writing of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5432546	28559908	ZP	2	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
4398355	25874938	CZ	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398355	25874938	CZ	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398355	25874938	GS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4398355	25874938	GS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398355	25874938	LY	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398355	25874938	LY	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398355	25874938	QL	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398355	25874938	SC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4398355	25874938	SC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398355	25874938	XG	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4398355	25874938	XL	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398355	25874938	XW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398355	25874938	YW	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398355	25874938	YW	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3152504	21714943	DKM	2	participated in implementation of the study and performed the hpsa tests	participated in implementation of the study and performed the hpsa tests	Performed the experiments	Investigation	YES
3152504	21714943	EH	2	participated in the conception, design and implementation of the study, statistical analysis, interpretation and writing of the manuscript	participated in the conception, design and implementation of the study, statistical analysis, interpretation and writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
3152504	21714943	EO	2	participated in the conception and design of the study, statistical analysis, interpretation and writing of the manuscript	participated in the conception and design of the study, statistical analysis, interpretation and writing of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
3152504	21714943	GN	2	participated in design and implementation of the study	participated in design and implementation of the study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3152504	21714943	JKT	2	participated in conception, design and implementation of the study	participated in conception, design and implementation of the study	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
3152504	21714943	LG	2	participated in design of the study, interpretation and writing of the manuscript	participated in design of the study, interpretation and writing of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3152504	21714943	TT	2	participated in the conception and design of the study, statistical analysis, interpretation and writing of the manuscript	participated in the conception and design of the study, statistical analysis, interpretation and writing of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
6358745	30669500	All authors	PLoS52	contributed to this work	contributed to this work	-	-	NO
6358745	30669500	D.J.	PLoS52	conducted the study	conducted the study	Performed the experiments	Investigation	YES
6358745	30669500	G.Z.	PLoS52	designed the study|conducted the study|prepared the original draft	designed the study	Conceived and designed the experiments	Methodology	YES
6358745	30669500	G.Z.	PLoS52	designed the study|conducted the study|prepared the original draft	conducted the study	Performed the experiments	Investigation	YES
6358745	30669500	G.Z.	PLoS52	designed the study|conducted the study|prepared the original draft	prepared the original draft	Wrote the paper	Writing - Original Draft	YES
6358745	30669500	J.Q.	PLoS52	also organized and supervised this work	also organized and supervised this work	-	Supervision	YES
6358745	30669500	J.W.	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
6358745	30669500	L.H.	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
6358745	30669500	Q.G.	PLoS52	designed the study|revised the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
6358745	30669500	Q.G.	PLoS52	designed the study|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
6358745	30669500	X.L.	PLoS52	performed the experiments|also organized and supervised this work	performed the experiments	Performed the experiments	Investigation	YES
6358745	30669500	X.L.	PLoS52	performed the experiments|also organized and supervised this work	also organized and supervised this work	-	Supervision	YES
6358745	30669500	Y.L.	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5001205	27556924	All authors	2	contribute to the manuscript	contribute to the manuscript	-	-	NO
5001205	27556924	HHC	2	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5001205	27556924	YC	2	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5001205	27556924	YH	2	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5001205	27556924	YJ	2	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3348867	22462726	RZ	2	participated in the synthesis of samples and collection of data and experimental work and analysis	participated in the synthesis of samples and collection of data and experimental work and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5432559	28559897	AV	2	contributed to the conception of the work, conducted the experiments and analyzed the data	contributed to the conception of the work, conducted the experiments and analyzed the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
5432559	28559897	DP	2	conducted the experiments and contributed to the design of the work	conducted the experiments and contributed to the design of the work	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5432559	28559897	ED	2	conducted the statistical analysis, contributed to data interpretation and edited the manuscript	conducted the statistical analysis, contributed to data interpretation and edited the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5432559	28559897	ES	2	conducted the experiments	conducted the experiments	Performed the experiments	Investigation	YES
5432559	28559897	GA	2	conducted the experiments	conducted the experiments	Performed the experiments	Investigation	YES
5432559	28559897	JH	2	planned the study, analyzed and interpreted the data, drafted the manuscript and ultimately approved the version to be published	planned the study, analyzed and interpreted the data, drafted the manuscript and ultimately approved the version to be published	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
3161340	20836882	ES	2	read the articles, books and papers reviewed here and collaborated in writing the article	read the articles, books and papers reviewed here and collaborated in writing the article	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3161340	20836882	LS	2	read the articles, books and papers reviewed here and collaborated in writing the article	read the articles, books and papers reviewed here and collaborated in writing the article	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4398356	25875476	AF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398356	25875476	AF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398356	25875476	AF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398356	25875476	AF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398356	25875476	AF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398356	25875476	CS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398356	25875476	CS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4398356	25875476	CS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398356	25875476	GR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398356	25875476	GR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4398356	25875476	GR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398356	25875476	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398356	25875476	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398356	25875476	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398356	25875476	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398356	25875476	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398356	25875476	SJL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398356	25875476	SJL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4398356	25875476	SJL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398356	25875476	TK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398356	25875476	TK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398356	25875476	TK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398356	25875476	TK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398356	25875476	VD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398356	25875476	VD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4398356	25875476	VD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
3351364	22452882	All authors	2	designed the study|contributed to data analyses and to finalizing the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
3351364	22452882	All authors	2	designed the study|contributed to data analyses and to finalizing the manuscript	contributed to data analyses and to finalizing the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
3351364	22452882	HSS	2	initiated and prepared the draft	initiated and prepared the draft	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
3351364	22452882	JAO	2	conducted the extraction and method developments	conducted the extraction and method developments	Performed the experiments	Investigation|Methodology	YES
6313602	30545015	D.V.-F.	2	conceptualized this review	conceptualized this review	Conceived and designed the experiments	Conceptualization	YES
6313602	30545015	N.L.	2	conceptualized this review	conceptualized this review	Conceived and designed the experiments	Conceptualization	YES
5001206	27556158	GLJ	2	design and drafted the manuscript	design and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
5001206	27556158	LJC	2	design and drafted the manuscript	design and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
6358751	30650541	A.L.C.	CRediT	investigation	investigation	Performed the experiments	Investigation	YES
6358751	30650541	D.C.	CRediT	Conceptualization|resources|writing--review and editing|supervision|funding acquisition	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6358751	30650541	D.C.	CRediT	Conceptualization|resources|writing--review and editing|supervision|funding acquisition	resources	Contributed reagents/materials/analysis tools	Resources	YES
6358751	30650541	D.C.	CRediT	Conceptualization|resources|writing--review and editing|supervision|funding acquisition	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6358751	30650541	D.C.	CRediT	Conceptualization|resources|writing--review and editing|supervision|funding acquisition	supervision	-	Supervision	YES
6358751	30650541	D.C.	CRediT	Conceptualization|resources|writing--review and editing|supervision|funding acquisition	funding acquisition	-	Funding acquisition	YES
6358751	30650541	D.P.	CRediT	Conceptualization|methodology|resources|writing--review and editing|supervision|project administration|funding acquisition	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6358751	30650541	D.P.	CRediT	Conceptualization|methodology|resources|writing--review and editing|supervision|project administration|funding acquisition	methodology	Performed the experiments	Methodology	YES
6358751	30650541	D.P.	CRediT	Conceptualization|methodology|resources|writing--review and editing|supervision|project administration|funding acquisition	resources	Contributed reagents/materials/analysis tools	Resources	YES
6358751	30650541	D.P.	CRediT	Conceptualization|methodology|resources|writing--review and editing|supervision|project administration|funding acquisition	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6358751	30650541	D.P.	CRediT	Conceptualization|methodology|resources|writing--review and editing|supervision|project administration|funding acquisition	supervision	-	Supervision	YES
6358751	30650541	D.P.	CRediT	Conceptualization|methodology|resources|writing--review and editing|supervision|project administration|funding acquisition	project administration	-	Project administration	YES
6358751	30650541	D.P.	CRediT	Conceptualization|methodology|resources|writing--review and editing|supervision|project administration|funding acquisition	funding acquisition	-	Funding acquisition	YES
6358751	30650541	G.C.	CRediT	Conceptualization|methodology|resources|writing--original draft preparation|writing--review and editing|supervision|project administration|funding acquisition	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6358751	30650541	G.C.	CRediT	Conceptualization|methodology|resources|writing--original draft preparation|writing--review and editing|supervision|project administration|funding acquisition	methodology	Performed the experiments	Methodology	YES
6358751	30650541	G.C.	CRediT	Conceptualization|methodology|resources|writing--original draft preparation|writing--review and editing|supervision|project administration|funding acquisition	resources	Contributed reagents/materials/analysis tools	Resources	YES
6358751	30650541	G.C.	CRediT	Conceptualization|methodology|resources|writing--original draft preparation|writing--review and editing|supervision|project administration|funding acquisition	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6358751	30650541	G.C.	CRediT	Conceptualization|methodology|resources|writing--original draft preparation|writing--review and editing|supervision|project administration|funding acquisition	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6358751	30650541	G.C.	CRediT	Conceptualization|methodology|resources|writing--original draft preparation|writing--review and editing|supervision|project administration|funding acquisition	supervision	-	Supervision	YES
6358751	30650541	G.C.	CRediT	Conceptualization|methodology|resources|writing--original draft preparation|writing--review and editing|supervision|project administration|funding acquisition	project administration	-	Project administration	YES
6358751	30650541	G.C.	CRediT	Conceptualization|methodology|resources|writing--original draft preparation|writing--review and editing|supervision|project administration|funding acquisition	funding acquisition	-	Funding acquisition	YES
6358751	30650541	L.D.	CRediT	software|formal analysis|investigation|data curation|visualization	software	Contributed reagents/materials/analysis tools	Software	YES
6358751	30650541	L.D.	CRediT	software|formal analysis|investigation|data curation|visualization	formal analysis	Analyzed the data	Formal analysis	YES
6358751	30650541	L.D.	CRediT	software|formal analysis|investigation|data curation|visualization	investigation	Performed the experiments	Investigation	YES
6358751	30650541	L.D.	CRediT	software|formal analysis|investigation|data curation|visualization	data curation	Analyzed the data	Data curation	YES
6358751	30650541	L.D.	CRediT	software|formal analysis|investigation|data curation|visualization	visualization	Analyzed the data	Visualization	YES
6358751	30650541	R.C.	CRediT	Conceptualization|resources|writing--review and editing|supervision	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6358751	30650541	R.C.	CRediT	Conceptualization|resources|writing--review and editing|supervision	resources	Contributed reagents/materials/analysis tools	Resources	YES
6358751	30650541	R.C.	CRediT	Conceptualization|resources|writing--review and editing|supervision	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6358751	30650541	R.C.	CRediT	Conceptualization|resources|writing--review and editing|supervision	supervision	-	Supervision	YES
6358751	30650541	S.P.	CRediT	validation|investigation|writing--review and editing|visualization	validation	Performed the experiments	Validation	YES
6358751	30650541	S.P.	CRediT	validation|investigation|writing--review and editing|visualization	investigation	Performed the experiments	Investigation	YES
6358751	30650541	S.P.	CRediT	validation|investigation|writing--review and editing|visualization	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6358751	30650541	S.P.	CRediT	validation|investigation|writing--review and editing|visualization	visualization	Analyzed the data	Visualization	YES
3353163	22410001	AD	2	conceived the experiments	conceived the experiments	Conceived and designed the experiments	Conceptualization	YES
3353163	22410001	DP	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3353163	22410001	KL	2	conceived the experiments	conceived the experiments	Conceived and designed the experiments	Conceptualization	YES
3353163	22410001	MC	2	conceived the experiments	conceived the experiments	Conceived and designed the experiments	Conceptualization	YES
3353163	22410001	MR	2	reported all biological experiments	reported all biological experiments	-	-	NO
3353163	22410001	PLC	2	performed structural studies	performed structural studies	Performed the experiments	Investigation	YES
3353163	22410001	SLI	2	synthesised the iron oxide ferofluid	synthesised the iron oxide ferofluid	-	-	NO
3161341	20840784	All authors	2	participated in the design and planning of the study	participated in the design and planning of the study	Conceived and designed the experiments	Methodology	YES
4398357	25875659	DCR	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4398357	25875659	DCR	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398357	25875659	NML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398357	25875659	NML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398357	25875659	NML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398357	25875659	NML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398357	25875659	NT	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398357	25875659	PWN	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398357	25875659	SPF	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398357	25875659	SPF	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5432562	28559912	GN	PLoS52	performed the experiments|analyzed the data|finalized the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5432562	28559912	GN	PLoS52	performed the experiments|analyzed the data|finalized the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5432562	28559912	GN	PLoS52	performed the experiments|analyzed the data|finalized the manuscript	finalized the manuscript	Wrote the paper	Writing - Review & Editing	YES
5432562	28559912	LH	PLoS52	conceived the project and designed the experiments	conceived the project and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5432562	28559912	LP	PLoS52	finalized the manuscript	finalized the manuscript	Wrote the paper	Writing - Review & Editing	YES
5432562	28559912	LT	PLoS52	performed the experiments|finalized the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5432562	28559912	LT	PLoS52	performed the experiments|finalized the manuscript	finalized the manuscript	Wrote the paper	Writing - Review & Editing	YES
5432562	28559912	XC	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5432562	28559912	XM	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5432562	28559912	XiZ	PLoS52	conceived the project and designed the experiments	conceived the project and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5432562	28559912	XuZ	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5432562	28559912	YZ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
6358759	30586876	F.T.	2	conceived the review	conceived the review	Conceived and designed the experiments	Conceptualization	YES
6358759	30586876	T.U.	2	conceived the review|analyzed the references and wrote the manuscript|revised and reviewed the manuscript	conceived the review	Conceived and designed the experiments	Conceptualization	YES
6358759	30586876	T.U.	2	conceived the review|analyzed the references and wrote the manuscript|revised and reviewed the manuscript	analyzed the references and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6358759	30586876	T.U.	2	conceived the review|analyzed the references and wrote the manuscript|revised and reviewed the manuscript	revised and reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
3353240	22524792	FYL	PLoS52	initiated and designed the study and finalized the manuscript	initiated and designed the study and finalized the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
3353240	22524792	HFL	PLoS52	initiated and designed the study and finalized the manuscript	initiated and designed the study and finalized the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
3353240	22524792	HYC	PLoS52	performed all the calcuations	performed all the calcuations	Performed the experiments	Investigation	YES
3353240	22524792	JYC	PLoS52	performed all the calcuations	performed all the calcuations	Performed the experiments	Investigation	YES
3353240	22524792	SJ	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
3353240	22524792	TRJ	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5001207	27556419	CM	PLoS52	developed the algorithms and performed the tests|wrote the paper	developed the algorithms and performed the tests	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5001207	27556419	CM	PLoS52	developed the algorithms and performed the tests|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5001207	27556419	ES	PLoS52	conceived the idea of the paper	conceived the idea of the paper	Conceived and designed the experiments	Conceptualization	YES
5001207	27556419	IA	PLoS52	collected samples from qatar population and performed microarray	collected samples from qatar population and performed microarray	Performed the experiments	Investigation	YES
5001207	27556419	KSS	PLoS52	collected samples from qatar population and performed microarray	collected samples from qatar population and performed microarray	Performed the experiments	Investigation	YES
5001207	27556419	LC	PLoS52	conceived the idea of the paper|collected samples from qatar population and performed microarray	conceived the idea of the paper	Conceived and designed the experiments	Conceptualization	YES
5001207	27556419	LC	PLoS52	conceived the idea of the paper|collected samples from qatar population and performed microarray	collected samples from qatar population and performed microarray	Performed the experiments	Investigation	YES
5001207	27556419	MF	PLoS52	developed the algorithms and performed the tests	developed the algorithms and performed the tests	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5001207	27556419	SG	PLoS52	collected samples from qatar population and performed microarray	collected samples from qatar population and performed microarray	Performed the experiments	Investigation	YES
5001207	27556419	YC	PLoS52	conceived the idea of the paper|wrote the paper	conceived the idea of the paper	Conceived and designed the experiments	Conceptualization	YES
5001207	27556419	YC	PLoS52	conceived the idea of the paper|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5001207	27556419	YF	PLoS52	developed the algorithms and performed the tests|wrote the paper	developed the algorithms and performed the tests	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5001207	27556419	YF	PLoS52	developed the algorithms and performed the tests|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5001207	27556419	YH	PLoS52	conceived the idea of the paper|wrote the paper	conceived the idea of the paper	Conceived and designed the experiments	Conceptualization	YES
5001207	27556419	YH	PLoS52	conceived the idea of the paper|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3163172	21843356	AC	2	participated in study design	participated in study design	Conceived and designed the experiments	Methodology	YES
3163172	21843356	HR	2	participated in study design|wrote and edited the manuscript	participated in study design	Conceived and designed the experiments	Methodology	YES
3163172	21843356	HR	2	participated in study design|wrote and edited the manuscript	wrote and edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3163172	21843356	KV	2	conceived of the study|participated in study design|collected data|analyzed data|wrote and edited the manuscript	conceived of the study	Conceived and designed the experiments	Conceptualization	YES
3163172	21843356	KV	2	conceived of the study|participated in study design|collected data|analyzed data|wrote and edited the manuscript	participated in study design	Conceived and designed the experiments	Methodology	YES
3163172	21843356	KV	2	conceived of the study|participated in study design|collected data|analyzed data|wrote and edited the manuscript	collected data	Performed the experiments	Investigation	YES
3163172	21843356	KV	2	conceived of the study|participated in study design|collected data|analyzed data|wrote and edited the manuscript	analyzed data	Analyzed the data	Formal analysis	YES
3163172	21843356	KV	2	conceived of the study|participated in study design|collected data|analyzed data|wrote and edited the manuscript	wrote and edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3163172	21843356	MC	2	participated in study design|performed the statistical analysis|analyzed data|wrote and edited the manuscript	participated in study design	Conceived and designed the experiments	Methodology	YES
3163172	21843356	MC	2	participated in study design|performed the statistical analysis|analyzed data|wrote and edited the manuscript	performed the statistical analysis	Analyzed the data	Formal analysis	YES
3163172	21843356	MC	2	participated in study design|performed the statistical analysis|analyzed data|wrote and edited the manuscript	analyzed data	Analyzed the data	Formal analysis	YES
3163172	21843356	MC	2	participated in study design|performed the statistical analysis|analyzed data|wrote and edited the manuscript	wrote and edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3163172	21843356	RH	2	analyzed data|wrote and edited the manuscript	analyzed data	Analyzed the data	Formal analysis	YES
3163172	21843356	RH	2	analyzed data|wrote and edited the manuscript	wrote and edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3163172	21843356	VB	2	participated in study design|collected data|wrote and edited the manuscript	participated in study design	Conceived and designed the experiments	Methodology	YES
3163172	21843356	VB	2	participated in study design|collected data|wrote and edited the manuscript	collected data	Performed the experiments	Investigation	YES
3163172	21843356	VB	2	participated in study design|collected data|wrote and edited the manuscript	wrote and edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3354339	22333299	MIW	2	designed the proposed method and analyzed the data statistically	designed the proposed method and analyzed the data statistically	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
3354339	22333299	MKS	2	proposed, planned and supervised the whole work	proposed, planned and supervised the whole work	Conceived and designed the experiments	Conceptualization|Supervision	YES
3354339	22333299	NME	2	proposed, planned and supervised the whole work|coordinated the study and modified the text	proposed, planned and supervised the whole work	Conceived and designed the experiments	Conceptualization|Supervision	YES
3354339	22333299	NME	2	proposed, planned and supervised the whole work|coordinated the study and modified the text	coordinated the study and modified the text	-	Project administration	YES
3354339	22333299	SMS	2	carried out the experimental work	carried out the experimental work	Performed the experiments	Investigation	YES
6358822	30621300	A.L.-A.	2	provided constructive instructions in the methodology used for the preparation of this study, supervision of the manuscript, and funding acquisition	provided constructive instructions in the methodology used for the preparation of this study, supervision of the manuscript, and funding acquisition	Performed the experiments|Wrote the paper	Funding acquisition|Investigation|Methodology|Supervision|Writing - Original Draft	YES
6358822	30621300	C.R.-S.	2	provided the resources, conceived, and designed the experiments	provided the resources, conceived, and designed the experiments	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceptualization|Methodology|Resources	YES
6358822	30621300	F.J.B.	2	provided the resources, conceived, and designed the experiments	provided the resources, conceived, and designed the experiments	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceptualization|Methodology|Resources	YES
6358822	30621300	I.A.	2	developed the experiments and made the formal analysis|also wrote the manuscript	developed the experiments and made the formal analysis	Analyzed the data	Formal analysis	YES
6358822	30621300	I.A.	2	developed the experiments and made the formal analysis|also wrote the manuscript	also wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6358822	30621300	J.S.	2	provided constructive instructions in the methodology used for the preparation of this study, supervision of the manuscript, and funding acquisition	provided constructive instructions in the methodology used for the preparation of this study, supervision of the manuscript, and funding acquisition	Performed the experiments|Wrote the paper	Funding acquisition|Investigation|Methodology|Supervision|Writing - Original Draft	YES
6358822	30621300	M.A.G.-S.	2	provided constructive instructions in the methodology used for the preparation of this study, supervision of the manuscript, and funding acquisition	provided constructive instructions in the methodology used for the preparation of this study, supervision of the manuscript, and funding acquisition	Performed the experiments|Wrote the paper	Funding acquisition|Investigation|Methodology|Supervision|Writing - Original Draft	YES
6358822	30621300	U.F.-G.	2	developed the experiments and made the formal analysis|also wrote the manuscript	developed the experiments and made the formal analysis	Analyzed the data	Formal analysis	YES
6358822	30621300	U.F.-G.	2	developed the experiments and made the formal analysis|also wrote the manuscript	also wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6358822	30621300	V.M.	2	provided the resources, conceived, and designed the experiments	provided the resources, conceived, and designed the experiments	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceptualization|Methodology|Resources	YES
5432564	28559913	All authors	2	commented on the manuscript and consent with the submitted version	commented on the manuscript and consent with the submitted version	-	-	NO
5432564	28559913	DY	2	carried out the fieldwork and lab analyses	carried out the fieldwork and lab analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5432564	28559913	GL	2	carried out the fieldwork and lab analyses	carried out the fieldwork and lab analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5432564	28559913	SZ	2	did the data analysis and wrote the first manuscript draft	did the data analysis and wrote the first manuscript draft	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5432564	28559913	XHY	2	carried out the fieldwork and lab analyses	carried out the fieldwork and lab analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5432564	28559913	XJY	2	carried out the fieldwork and lab analyses	carried out the fieldwork and lab analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4398358	25875019	KY	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398358	25875019	LMH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Software programming|Noise mapping strategy	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398358	25875019	LMH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Software programming|Noise mapping strategy	Performed the experiments	Performed the experiments	Investigation	YES
4398358	25875019	LMH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Software programming|Noise mapping strategy	Analyzed the data	Analyzed the data	Formal analysis	YES
4398358	25875019	LMH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Software programming|Noise mapping strategy	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398358	25875019	LMH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Software programming|Noise mapping strategy	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398358	25875019	LMH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Software programming|Noise mapping strategy	Software programming	Contributed reagents/materials/analysis tools	Software	YES
4398358	25875019	LMH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Software programming|Noise mapping strategy	Noise mapping strategy	-	-	NO
4398358	25875019	MND	PLoS5	Noise mapping strategy	Noise mapping strategy	-	-	NO
4398358	25875019	SAB	PLoS5	Software programming	Software programming	Contributed reagents/materials/analysis tools	Software	YES
4398358	25875019	ZH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398358	25875019	ZH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398358	25875019	ZH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3163506	21801351	ASF	2	supervised the statistical analysis, and contributed to data discussion and manuscript preparation	supervised the statistical analysis, and contributed to data discussion and manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Supervision|Writing - Original Draft	YES
3163506	21801351	CF	2	was responsible for clinical coordination and patient interaction, and contributed to data discussion and manuscript revision	was responsible for clinical coordination and patient interaction, and contributed to data discussion and manuscript revision	Wrote the paper	Project administration|Writing - Review & Editing	YES
3163506	21801351	DG	2	was responsible for flow cytometry supervision, and contributed to data discussion and manuscript revision	was responsible for flow cytometry supervision, and contributed to data discussion and manuscript revision	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Review & Editing	YES
3163506	21801351	DL	2	was responsible for flow cytometry analysis and cd4 assessment, and contributed to manuscript revision	was responsible for flow cytometry analysis and cd4 assessment, and contributed to manuscript revision	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
3163506	21801351	EP	2	contributed to data discussion and manuscript revision	contributed to data discussion and manuscript revision	Wrote the paper	Writing - Review & Editing	YES
3163506	21801351	IS	2	was responsible for supervising clinical coordination and patient interaction, and contributed to data discussion and manuscript preparation	was responsible for supervising clinical coordination and patient interaction, and contributed to data discussion and manuscript preparation	Wrote the paper	Project administration|Supervision|Writing - Original Draft	YES
3163506	21801351	LA	2	was responsible for study design, data management, data analysis, and manuscript and illustration preparation	was responsible for study design, data management, data analysis, and manuscript and illustration preparation	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Data curation|Formal analysis|Methodology|Visualization|Writing - Original Draft	YES
3163506	21801351	LJM	2	was responsible for supervising immunology laboratory assessments, and contributed to study design, critical analysis and manuscript preparation	was responsible for supervising immunology laboratory assessments, and contributed to study design, critical analysis and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Supervision|Writing - Original Draft	YES
3163506	21801351	NJC	2	was responsible for lipid assessment, and contributed to critical analysis, data discussion and manuscript preparation	was responsible for lipid assessment, and contributed to critical analysis, data discussion and manuscript preparation	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft	YES
3163506	21801351	WS	2	was responsible for clinical laboratory supervision, and contributed to data discussion and manuscript preparation	was responsible for clinical laboratory supervision, and contributed to data discussion and manuscript preparation	Wrote the paper	Supervision|Writing - Original Draft	YES
3163506	21801351	XY	2	was responsible for statistical analysis, and contributed to data discussion and manuscript revision	was responsible for statistical analysis, and contributed to data discussion and manuscript revision	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
3359168	22462769	JG	2	produced samples, carried out acquisition of data, performed data analysis and data interpretation	produced samples, carried out acquisition of data, performed data analysis and data interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3359168	22462769	JH	2	designed and built the experimental equipment and contributed to the acquisition of the data	designed and built the experimental equipment and contributed to the acquisition of the data	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources	YES
3359168	22462769	KT	2	produced samples, carried out acquisition of data, performed data analysis and data interpretation	produced samples, carried out acquisition of data, performed data analysis and data interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3359168	22462769	LG	2	conceived the study, participated in the design and co-ordination of the experiments and data interpretation and helped draft the manuscript	conceived the study, participated in the design and co-ordination of the experiments and data interpretation and helped draft the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Project administration|Writing - Original Draft	YES
3359168	22462769	NJT	2	designed and built the experimental equipment and contributed to the acquisition of the data	designed and built the experimental equipment and contributed to the acquisition of the data	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources	YES
3359168	22462769	TJW	2	conceived the study, participated in the design and co-ordination of the experiments and data interpretation and helped draft the manuscript	conceived the study, participated in the design and co-ordination of the experiments and data interpretation and helped draft the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Project administration|Writing - Original Draft	YES
5001210	27556295	JR	2	managed and participated in the peer-review of icibm15 manuscripts, excluding those on which they were authors, and handled the editorial process of this supplement|wrote the article, which was read and approved by all authors	managed and participated in the peer-review of icibm15 manuscripts, excluding those on which they were authors, and handled the editorial process of this supplement	Wrote the paper	Writing - Review & Editing	YES
5001210	27556295	JR	2	managed and participated in the peer-review of icibm15 manuscripts, excluding those on which they were authors, and handled the editorial process of this supplement|wrote the article, which was read and approved by all authors	wrote the article, which was read and approved by all authors	Wrote the paper	Writing - Original Draft	YES
5001210	27556295	KH	2	managed and participated in the peer-review of icibm15 manuscripts, excluding those on which they were authors, and handled the editorial process of this supplement|wrote the article, which was read and approved by all authors	managed and participated in the peer-review of icibm15 manuscripts, excluding those on which they were authors, and handled the editorial process of this supplement	Wrote the paper	Writing - Review & Editing	YES
5001210	27556295	KH	2	managed and participated in the peer-review of icibm15 manuscripts, excluding those on which they were authors, and handled the editorial process of this supplement|wrote the article, which was read and approved by all authors	wrote the article, which was read and approved by all authors	Wrote the paper	Writing - Original Draft	YES
5001210	27556295	LC	2	supported the post-acceptance manuscript processing	supported the post-acceptance manuscript processing	-	-	NO
5001210	27556295	LL	2	supported the post-acceptance manuscript processing	supported the post-acceptance manuscript processing	-	-	NO
5001210	27556295	YH	2	supported the post-acceptance manuscript processing	supported the post-acceptance manuscript processing	-	-	NO
5001210	27556295	YL	2	managed and participated in the peer-review of icibm15 manuscripts, excluding those on which they were authors, and handled the editorial process of this supplement|wrote the article, which was read and approved by all authors	managed and participated in the peer-review of icibm15 manuscripts, excluding those on which they were authors, and handled the editorial process of this supplement	Wrote the paper	Writing - Review & Editing	YES
5001210	27556295	YL	2	managed and participated in the peer-review of icibm15 manuscripts, excluding those on which they were authors, and handled the editorial process of this supplement|wrote the article, which was read and approved by all authors	wrote the article, which was read and approved by all authors	Wrote the paper	Writing - Original Draft	YES
5001210	27556295	ZZ	2	managed and participated in the peer-review of icibm15 manuscripts, excluding those on which they were authors, and handled the editorial process of this supplement|wrote the article, which was read and approved by all authors	managed and participated in the peer-review of icibm15 manuscripts, excluding those on which they were authors, and handled the editorial process of this supplement	Wrote the paper	Writing - Review & Editing	YES
5001210	27556295	ZZ	2	managed and participated in the peer-review of icibm15 manuscripts, excluding those on which they were authors, and handled the editorial process of this supplement|wrote the article, which was read and approved by all authors	wrote the article, which was read and approved by all authors	Wrote the paper	Writing - Original Draft	YES
6313677	30274269	A. Analyzed	2	data and reviewed the manuscript	data and reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
6313677	30274269	B.D.	2	supervised the collection of data and revised the draft manuscript	supervised the collection of data and revised the draft manuscript	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
6313677	30274269	C.A.-B.	2	conceived the idea, designed the experiments and analyzed the data	conceived the idea, designed the experiments and analyzed the data	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
6313677	30274269	C.A.D.	2	analyzed and interpreted the data collected	analyzed and interpreted the data collected	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6313677	30274269	E.T.A.	2	drafted the first manuscript	drafted the first manuscript	Wrote the paper	Writing - Original Draft	YES
6313677	30274269	F.S.	2	recruited the patients and collected data	recruited the patients and collected data	Performed the experiments	Investigation	YES
6313677	30274269	I.E.	2	supervised the clinical characterization and ensured quality of the laboratory	supervised the clinical characterization and ensured quality of the laboratory	Performed the experiments	Investigation|Supervision	YES
6313677	30274269	K.H.O.	2	entered and analyzed data and revised the manuscript	entered and analyzed data and revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5432567	28559898	JD	PLoS52	performed the experiments|revised manuscript	performed the experiments	Performed the experiments	Investigation	YES
5432567	28559898	JD	PLoS52	performed the experiments|revised manuscript	revised manuscript	Wrote the paper	Writing - Review & Editing	YES
5432567	28559898	JF	PLoS52	designed the study|provided experimental materials	designed the study	Conceived and designed the experiments	Methodology	YES
5432567	28559898	JF	PLoS52	designed the study|provided experimental materials	provided experimental materials	Contributed reagents/materials/analysis tools	Resources	YES
5432567	28559898	MM	PLoS52	performed the experiments|revised manuscript	performed the experiments	Performed the experiments	Investigation	YES
5432567	28559898	MM	PLoS52	performed the experiments|revised manuscript	revised manuscript	Wrote the paper	Writing - Review & Editing	YES
5432567	28559898	MV	PLoS52	designed the study|performed the experiments|analyzed results and wrote manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5432567	28559898	MV	PLoS52	designed the study|performed the experiments|analyzed results and wrote manuscript	performed the experiments	Performed the experiments	Investigation	YES
5432567	28559898	MV	PLoS52	designed the study|performed the experiments|analyzed results and wrote manuscript	analyzed results and wrote manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5432567	28559898	ZZ	PLoS52	conceived and supervised the study|designed the study|revised manuscript	conceived and supervised the study	Conceived and designed the experiments	Conceptualization|Supervision	YES
5432567	28559898	ZZ	PLoS52	conceived and supervised the study|designed the study|revised manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5432567	28559898	ZZ	PLoS52	conceived and supervised the study|designed the study|revised manuscript	revised manuscript	Wrote the paper	Writing - Review & Editing	YES
6358859	30650593	G.Q.	CRediT	writing--review and editing|supervision|funding acquisition	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6358859	30650593	G.Q.	CRediT	writing--review and editing|supervision|funding acquisition	supervision	-	Supervision	YES
6358859	30650593	G.Q.	CRediT	writing--review and editing|supervision|funding acquisition	funding acquisition	-	Funding acquisition	YES
6358859	30650593	J.H.	CRediT	writing--review and editing|funding acquisition	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6358859	30650593	J.H.	CRediT	writing--review and editing|funding acquisition	funding acquisition	-	Funding acquisition	YES
6358859	30650593	J.S.	CRediT	resources	resources	Contributed reagents/materials/analysis tools	Resources	YES
6358859	30650593	M.F.	CRediT	Conceptualization|methodology|formal analysis|investigation|writing--original draft preparation|visualization	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6358859	30650593	M.F.	CRediT	Conceptualization|methodology|formal analysis|investigation|writing--original draft preparation|visualization	methodology	Performed the experiments	Methodology	YES
6358859	30650593	M.F.	CRediT	Conceptualization|methodology|formal analysis|investigation|writing--original draft preparation|visualization	formal analysis	Analyzed the data	Formal analysis	YES
6358859	30650593	M.F.	CRediT	Conceptualization|methodology|formal analysis|investigation|writing--original draft preparation|visualization	investigation	Performed the experiments	Investigation	YES
6358859	30650593	M.F.	CRediT	Conceptualization|methodology|formal analysis|investigation|writing--original draft preparation|visualization	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6358859	30650593	M.F.	CRediT	Conceptualization|methodology|formal analysis|investigation|writing--original draft preparation|visualization	visualization	Analyzed the data	Visualization	YES
6358859	30650593	M.P.	CRediT	writing--review and editing|supervision|project administration|funding acquisition	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6358859	30650593	M.P.	CRediT	writing--review and editing|supervision|project administration|funding acquisition	supervision	-	Supervision	YES
6358859	30650593	M.P.	CRediT	writing--review and editing|supervision|project administration|funding acquisition	project administration	-	Project administration	YES
6358859	30650593	M.P.	CRediT	writing--review and editing|supervision|project administration|funding acquisition	funding acquisition	-	Funding acquisition	YES
6358859	30650593	R.R.	CRediT	Conceptualization|methodology|formal analysis|investigation|writing--original draft preparation|visualization	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6358859	30650593	R.R.	CRediT	Conceptualization|methodology|formal analysis|investigation|writing--original draft preparation|visualization	methodology	Performed the experiments	Methodology	YES
6358859	30650593	R.R.	CRediT	Conceptualization|methodology|formal analysis|investigation|writing--original draft preparation|visualization	formal analysis	Analyzed the data	Formal analysis	YES
6358859	30650593	R.R.	CRediT	Conceptualization|methodology|formal analysis|investigation|writing--original draft preparation|visualization	investigation	Performed the experiments	Investigation	YES
6358859	30650593	R.R.	CRediT	Conceptualization|methodology|formal analysis|investigation|writing--original draft preparation|visualization	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6358859	30650593	R.R.	CRediT	Conceptualization|methodology|formal analysis|investigation|writing--original draft preparation|visualization	visualization	Analyzed the data	Visualization	YES
4398359	25875026	MEL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398359	25875026	MEL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398359	25875026	MEL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398359	25875026	MEL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398359	25875026	MEL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398359	25875026	MPP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398359	25875026	MPP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398359	25875026	MPP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3359257	22483270	BAS	2	were involved in revising the manuscript	were involved in revising the manuscript	Wrote the paper	Writing - Review & Editing	YES
3359257	22483270	JW	2	to carry out their synthesis and characterization experiments|were also involved in the drafting of the manuscript	to carry out their synthesis and characterization experiments	Performed the experiments	Investigation	YES
3359257	22483270	JW	2	to carry out their synthesis and characterization experiments|were also involved in the drafting of the manuscript	were also involved in the drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
3359257	22483270	MH	2	performed the antibacterial tests	performed the antibacterial tests	Performed the experiments	Investigation	YES
3359257	22483270	NMR	2	spectral analyses and elemental analysis	spectral analyses and elemental analysis	Analyzed the data	Formal analysis	YES
3359257	22483270	SHK	2	to carry out their synthesis and characterization experiments|were also involved in the drafting of the manuscript	to carry out their synthesis and characterization experiments	Performed the experiments	Investigation	YES
3359257	22483270	SHK	2	to carry out their synthesis and characterization experiments|were also involved in the drafting of the manuscript	were also involved in the drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
3359257	22483270	SY	2	were involved in revising the manuscript	were involved in revising the manuscript	Wrote the paper	Writing - Review & Editing	YES
3163507	21801434	BM	2	acquired and/or interpreted the data	acquired and/or interpreted the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3163507	21801434	CTY	2	acquired and/or interpreted the data|revised the manuscript	acquired and/or interpreted the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3163507	21801434	CTY	2	acquired and/or interpreted the data|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
3163507	21801434	KN	2	programmed the model	programmed the model	Performed the experiments|Contributed reagents/materials/analysis tools	Methodology|Software	YES
3163507	21801434	KWK	2	acquired and/or interpreted the data|revised the manuscript	acquired and/or interpreted the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3163507	21801434	KWK	2	acquired and/or interpreted the data|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
3163507	21801434	LD	2	acquired and/or interpreted the data|revised the manuscript	acquired and/or interpreted the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3163507	21801434	LD	2	acquired and/or interpreted the data|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
3163507	21801434	MCB	2	acquired and/or interpreted the data|revised the manuscript	acquired and/or interpreted the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3163507	21801434	MCB	2	acquired and/or interpreted the data|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
3163507	21801434	RSB	2	designed the study concept|analyzed results and wrote the manuscript|revised the manuscript	designed the study concept	Conceived and designed the experiments	Conceptualization|Methodology	YES
3163507	21801434	RSB	2	designed the study concept|analyzed results and wrote the manuscript|revised the manuscript	analyzed results and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3163507	21801434	RSB	2	designed the study concept|analyzed results and wrote the manuscript|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
3163507	21801434	SK	2	acquired and/or interpreted the data	acquired and/or interpreted the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5001211	27556636	SCJ	2	conceived study|supervised the study|wrote the manuscript	conceived study	Conceived and designed the experiments	Conceptualization	YES
5001211	27556636	SCJ	2	conceived study|supervised the study|wrote the manuscript	supervised the study	-	Supervision	YES
5001211	27556636	SCJ	2	conceived study|supervised the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5001211	27556636	YC	2	conceived study|performed the analysis|wrote the manuscript	conceived study	Conceived and designed the experiments	Conceptualization	YES
5001211	27556636	YC	2	conceived study|performed the analysis|wrote the manuscript	performed the analysis	Performed the experiments	Investigation	YES
5001211	27556636	YC	2	conceived study|performed the analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6313719	30249972	A.A.	2	supervised the project	supervised the project	-	Supervision	YES
6313719	30249972	All authors	2	contributed significantly to data collection and compilation	contributed significantly to data collection and compilation	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
6313719	30249972	B.J.P.	2	prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
4398360	25875444	MR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398360	25875444	MR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398360	25875444	MR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398360	25875444	RH	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398360	25875444	RS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398360	25875444	RS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3365867	22390207	NGH	2	carried out all experiments and prepared the final manuscript	carried out all experiments and prepared the final manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5432568	28559896	CP	2	guided the analyses	guided the analyses	Analyzed the data	Formal analysis|Supervision	YES
5432568	28559896	JD	2	provided the experimental framework	provided the experimental framework	Performed the experiments	Investigation	YES
5432568	28559896	NT	2	contributed to the conceptualization of the project and design of the experiment|guided the analyses	contributed to the conceptualization of the project and design of the experiment	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
5432568	28559896	NT	2	contributed to the conceptualization of the project and design of the experiment|guided the analyses	guided the analyses	Analyzed the data	Formal analysis|Supervision	YES
5432568	28559896	ST	2	contributed to the conceptualization of the project and design of the experiment|collected and analyzed the data|drafted the article	contributed to the conceptualization of the project and design of the experiment	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
5432568	28559896	ST	2	contributed to the conceptualization of the project and design of the experiment|collected and analyzed the data|drafted the article	collected and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5432568	28559896	ST	2	contributed to the conceptualization of the project and design of the experiment|collected and analyzed the data|drafted the article	drafted the article	Wrote the paper	Writing - Original Draft	YES
5432568	28559896	all authors	2	contributed to the critical revision of the article	contributed to the critical revision of the article	Wrote the paper	Writing - Review & Editing	YES
6313724	30336607	All the authors	2	have critically discussed, read and approved the final manuscript	have critically discussed, read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6313724	30336607	J.A.G.Z.	2	were involved in direct patient care|wrote the manuscript	were involved in direct patient care	Performed the experiments	Investigation	YES
6313724	30336607	J.A.G.Z.	2	were involved in direct patient care|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6313724	30336607	M.C.-P.	2	were involved in direct patient care	were involved in direct patient care	Performed the experiments	Investigation	YES
6313724	30336607	M.R.A.	2	were involved in direct patient care	were involved in direct patient care	Performed the experiments	Investigation	YES
6313724	30336607	O.V.M.	2	performed microbiological tests	performed microbiological tests	Performed the experiments	Investigation	YES
3163508	21843351	DH	2	conceived of the study, helped implement and collect data, and reviewed and revised the manuscript	conceived of the study, helped implement and collect data, and reviewed and revised the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Review & Editing	YES
3163508	21843351	FS	2	helped design and implement the study and also helped to draft the manuscript	helped design and implement the study and also helped to draft the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
3163508	21843351	MKK	2	performed all statistical analyses and reviewed the manuscript	performed all statistical analyses and reviewed the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
3163508	21843351	NF	2	reviewed and revised the manuscript	reviewed and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
3163508	21843351	NJSL	2	collected data and drafted the manuscript	collected data and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3163508	21843351	NNT	2	helped design and implement the study	helped design and implement the study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3163508	21843351	SL	2	helped implement the study and also helped draft the manuscript	helped implement the study and also helped draft the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3163508	21843351	TM	2	reviewed and revised the manuscript	reviewed and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
3163508	21843351	WLD	2	reviewed and revised the manuscript	reviewed and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4398361	25875493	EAS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398361	25875493	EAS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398361	25875493	EAS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398361	25875493	KW	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4398361	25875493	KW	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4398361	25875493	LT	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4398361	25875493	LT	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4398361	25875493	PAW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398361	25875493	PAW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398361	25875493	PAW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398361	25875493	PAW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398361	25875493	RS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4398361	25875493	RS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4398361	25875493	VT	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4398361	25875493	VT	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
6358885	30646496	D.C.D.	CRediT	methodology|formal analysis|investigation|data curation|writing--review and editing	methodology	Performed the experiments	Methodology	YES
6358885	30646496	D.C.D.	CRediT	methodology|formal analysis|investigation|data curation|writing--review and editing	formal analysis	Analyzed the data	Formal analysis	YES
6358885	30646496	D.C.D.	CRediT	methodology|formal analysis|investigation|data curation|writing--review and editing	investigation	Performed the experiments	Investigation	YES
6358885	30646496	D.C.D.	CRediT	methodology|formal analysis|investigation|data curation|writing--review and editing	data curation	Analyzed the data	Data curation	YES
6358885	30646496	D.C.D.	CRediT	methodology|formal analysis|investigation|data curation|writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6358885	30646496	M.C.D.	CRediT	conceptualization|methodology|investigation|resources|data curation|writing--original draft preparation|writing--review and editing|supervision	conceptualization	Conceived and designed the experiments	Conceptualization	YES
6358885	30646496	M.C.D.	CRediT	conceptualization|methodology|investigation|resources|data curation|writing--original draft preparation|writing--review and editing|supervision	methodology	Performed the experiments	Methodology	YES
6358885	30646496	M.C.D.	CRediT	conceptualization|methodology|investigation|resources|data curation|writing--original draft preparation|writing--review and editing|supervision	investigation	Performed the experiments	Investigation	YES
6358885	30646496	M.C.D.	CRediT	conceptualization|methodology|investigation|resources|data curation|writing--original draft preparation|writing--review and editing|supervision	resources	Contributed reagents/materials/analysis tools	Resources	YES
6358885	30646496	M.C.D.	CRediT	conceptualization|methodology|investigation|resources|data curation|writing--original draft preparation|writing--review and editing|supervision	data curation	Analyzed the data	Data curation	YES
6358885	30646496	M.C.D.	CRediT	conceptualization|methodology|investigation|resources|data curation|writing--original draft preparation|writing--review and editing|supervision	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6358885	30646496	M.C.D.	CRediT	conceptualization|methodology|investigation|resources|data curation|writing--original draft preparation|writing--review and editing|supervision	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6358885	30646496	M.C.D.	CRediT	conceptualization|methodology|investigation|resources|data curation|writing--original draft preparation|writing--review and editing|supervision	supervision	-	Supervision	YES
6358885	30646496	M.E.L.I.	CRediT	methodology|formal analysis|investigation|data curation|writing--review and editing	methodology	Performed the experiments	Methodology	YES
6358885	30646496	M.E.L.I.	CRediT	methodology|formal analysis|investigation|data curation|writing--review and editing	formal analysis	Analyzed the data	Formal analysis	YES
6358885	30646496	M.E.L.I.	CRediT	methodology|formal analysis|investigation|data curation|writing--review and editing	investigation	Performed the experiments	Investigation	YES
6358885	30646496	M.E.L.I.	CRediT	methodology|formal analysis|investigation|data curation|writing--review and editing	data curation	Analyzed the data	Data curation	YES
6358885	30646496	M.E.L.I.	CRediT	methodology|formal analysis|investigation|data curation|writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6358885	30646496	R.B.d.B.V.	CRediT	conceptualization|methodology|investigation|resources|data curation|writing--original draft preparation|writing--review and editing|supervision	conceptualization	Conceived and designed the experiments	Conceptualization	YES
6358885	30646496	R.B.d.B.V.	CRediT	conceptualization|methodology|investigation|resources|data curation|writing--original draft preparation|writing--review and editing|supervision	methodology	Performed the experiments	Methodology	YES
6358885	30646496	R.B.d.B.V.	CRediT	conceptualization|methodology|investigation|resources|data curation|writing--original draft preparation|writing--review and editing|supervision	investigation	Performed the experiments	Investigation	YES
6358885	30646496	R.B.d.B.V.	CRediT	conceptualization|methodology|investigation|resources|data curation|writing--original draft preparation|writing--review and editing|supervision	resources	Contributed reagents/materials/analysis tools	Resources	YES
6358885	30646496	R.B.d.B.V.	CRediT	conceptualization|methodology|investigation|resources|data curation|writing--original draft preparation|writing--review and editing|supervision	data curation	Analyzed the data	Data curation	YES
6358885	30646496	R.B.d.B.V.	CRediT	conceptualization|methodology|investigation|resources|data curation|writing--original draft preparation|writing--review and editing|supervision	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6358885	30646496	R.B.d.B.V.	CRediT	conceptualization|methodology|investigation|resources|data curation|writing--original draft preparation|writing--review and editing|supervision	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6358885	30646496	R.B.d.B.V.	CRediT	conceptualization|methodology|investigation|resources|data curation|writing--original draft preparation|writing--review and editing|supervision	supervision	-	Supervision	YES
6313726	30423855	K.S.	2	acquired data	acquired data	Performed the experiments	Investigation	YES
6313726	30423855	M.S.	2	drafted the article	drafted the article	Wrote the paper	Writing - Original Draft	YES
6313726	30423855	N.M.	2	approved the manuscript	approved the manuscript	-	-	NO
6313726	30423855	O.R.	2	acquired data	acquired data	Performed the experiments	Investigation	YES
6313726	30423855	S.Y.	2	acquired data	acquired data	Performed the experiments	Investigation	YES
6313726	30423855	T.K.	2	designed the study and analyzed data|acquired data|drafted the article	designed the study and analyzed data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
6313726	30423855	T.K.	2	designed the study and analyzed data|acquired data|drafted the article	acquired data	Performed the experiments	Investigation	YES
6313726	30423855	T.K.	2	designed the study and analyzed data|acquired data|drafted the article	drafted the article	Wrote the paper	Writing - Original Draft	YES
6313726	30423855	T.S.	2	designed the study and analyzed data|acquired data|drafted the article	designed the study and analyzed data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
6313726	30423855	T.S.	2	designed the study and analyzed data|acquired data|drafted the article	acquired data	Performed the experiments	Investigation	YES
6313726	30423855	T.S.	2	designed the study and analyzed data|acquired data|drafted the article	drafted the article	Wrote the paper	Writing - Original Draft	YES
6313726	30423855	Y.S.	2	drafted the article	drafted the article	Wrote the paper	Writing - Original Draft	YES
5001229	27557078	AZ	2	designed the study, conducted the analysis, and drafted the manuscript	designed the study, conducted the analysis, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5001229	27557078	BL	2	participated design of the study, and drafting of the manuscript	participated design of the study, and drafting of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5001229	27557078	BX	2	participated design of the study, and drafting of the manuscript	participated design of the study, and drafting of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5001229	27557078	CB	2	participated design of the study, and drafting of the manuscript	participated design of the study, and drafting of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5001229	27557078	ML	2	contributed in functional analysis of alternative splicing events	contributed in functional analysis of alternative splicing events	-	-	NO
5001229	27557078	MoRF	2	in alternatively spliced regions	in alternatively spliced regions	-	-	NO
5001229	27557078	WF	2	participated design of the study, and drafting of the manuscript	participated design of the study, and drafting of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5001229	27557078	YL	2	designed the study, conducted the analysis, and drafted the manuscript	designed the study, conducted the analysis, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5001229	27557078	YW	2	designed the study, conducted the analysis, and drafted the manuscript	designed the study, conducted the analysis, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
4396065	25918715	Detu Zhu	2	are equal contributors	are equal contributors	-	-	NO
4396065	25918715	Yumei Luo	2	are equal contributors	are equal contributors	-	-	NO
3169441	21827673	All authors	2	provided critical review of the manuscript and approved the final version to be published	provided critical review of the manuscript and approved the final version to be published	Wrote the paper	Writing - Review & Editing	YES
3169441	21827673	DAC	2	conceived and designed the study|drafted the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3169441	21827673	DAC	2	conceived and designed the study|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
3169441	21827673	DH	2	extracted and analyzed the case surveillance data	extracted and analyzed the case surveillance data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3169441	21827673	EW	2	extracted and analyzed the case surveillance data	extracted and analyzed the case surveillance data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3169441	21827673	HIV	2	subtyping and analyzed the data	subtyping and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3169441	21827673	MG	2	conceived and designed the study|extracted and analyzed the case surveillance data	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3169441	21827673	MG	2	conceived and designed the study|extracted and analyzed the case surveillance data	extracted and analyzed the case surveillance data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3169441	21827673	MK	2	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3169441	21827673	MLR	2	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3169441	21827673	MS	2	conceived and designed the study|drafted the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3169441	21827673	MS	2	conceived and designed the study|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
3169441	21827673	PT	2	performed the hiv screen testing and confirmation	performed the hiv screen testing and confirmation	Performed the experiments	Investigation	YES
5432570	28559904	AB	2	participated in the experimental design	participated in the experimental design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5432570	28559904	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5432570	28559904	JB	2	participated in data analysis	participated in data analysis	Analyzed the data	Formal analysis	YES
5432570	28559904	KP	2	participated in the experimental design	participated in the experimental design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5432570	28559904	MR	2	participated in the experimental design|conceived the idea and participated in the interpretation of results and preparation of manuscript	participated in the experimental design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5432570	28559904	MR	2	participated in the experimental design|conceived the idea and participated in the interpretation of results and preparation of manuscript	conceived the idea and participated in the interpretation of results and preparation of manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
5432570	28559904	QM	2	performed the data and genome-wide association analyses and prepared the manuscript	performed the data and genome-wide association analyses and prepared the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4398362	25875918	JP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398362	25875918	JP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398362	25875918	JP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398362	25875918	MP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398362	25875918	MP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398362	25875918	MP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398362	25875918	RA	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398362	25875918	RA	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398362	25875918	TF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398362	25875918	TF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398362	25875918	TF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398362	25875918	TF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3377924	22044685	BMA	2	performed the hydrolysis reaction optimization and its characterization study	performed the hydrolysis reaction optimization and its characterization study	Performed the experiments	Investigation	YES
3377924	22044685	JS	2	developed the concept, analyzed the data and drafted the manuscript	developed the concept, analyzed the data and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
3377924	22044685	NS	2	advised on the methods of tests	advised on the methods of tests	Performed the experiments	-	YES
3179691	21831310	AK	2	revised the manuscript critically for important intellectual content	revised the manuscript critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
3179691	21831310	All authors	2	participated in data collection, and revised and approved the final manuscript	participated in data collection, and revised and approved the final manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
3179691	21831310	CC	2	revised the manuscript critically for important intellectual content	revised the manuscript critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
3179691	21831310	MES	2	designed the study, and analyzed and interpreted the data|also wrote the first draft of the manuscript|revised the manuscript critically for important intellectual content	designed the study, and analyzed and interpreted the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
3179691	21831310	MES	2	designed the study, and analyzed and interpreted the data|also wrote the first draft of the manuscript|revised the manuscript critically for important intellectual content	also wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
3179691	21831310	MES	2	designed the study, and analyzed and interpreted the data|also wrote the first draft of the manuscript|revised the manuscript critically for important intellectual content	revised the manuscript critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
3179691	21831310	NL	2	designed the study, and analyzed and interpreted the data|revised the manuscript critically for important intellectual content	designed the study, and analyzed and interpreted the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
3179691	21831310	NL	2	designed the study, and analyzed and interpreted the data|revised the manuscript critically for important intellectual content	revised the manuscript critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
3179691	21831310	OS	2	designed the study, and analyzed and interpreted the data|revised the manuscript critically for important intellectual content	designed the study, and analyzed and interpreted the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
3179691	21831310	OS	2	designed the study, and analyzed and interpreted the data|revised the manuscript critically for important intellectual content	revised the manuscript critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
3179691	21831310	PC	2	designed the study, and analyzed and interpreted the data|revised the manuscript critically for important intellectual content	designed the study, and analyzed and interpreted the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
3179691	21831310	PC	2	designed the study, and analyzed and interpreted the data|revised the manuscript critically for important intellectual content	revised the manuscript critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
3179691	21831310	RV	2	contributed to the design of the study	contributed to the design of the study	Conceived and designed the experiments	Methodology	YES
6313749	30347791	A.P.R.	CRediT	Methodology|Investigation|Writing - review & editing	Methodology	Performed the experiments	Methodology	YES
6313749	30347791	A.P.R.	CRediT	Methodology|Investigation|Writing - review & editing	Investigation	Performed the experiments	Investigation	YES
6313749	30347791	A.P.R.	CRediT	Methodology|Investigation|Writing - review & editing	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
6313749	30347791	A.R.M.	CRediT	Methodology|Investigation|Writing - review & editing	Methodology	Performed the experiments	Methodology	YES
6313749	30347791	A.R.M.	CRediT	Methodology|Investigation|Writing - review & editing	Investigation	Performed the experiments	Investigation	YES
6313749	30347791	A.R.M.	CRediT	Methodology|Investigation|Writing - review & editing	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
6313749	30347791	A.Y.C.	CRediT	Conceptualization|Methodology|Validation|Formal analysis|Investigation|Resources|Data curation|Writing - original draft|Writing - review & editing|Supervision|Funding acquisition	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6313749	30347791	A.Y.C.	CRediT	Conceptualization|Methodology|Validation|Formal analysis|Investigation|Resources|Data curation|Writing - original draft|Writing - review & editing|Supervision|Funding acquisition	Methodology	Performed the experiments	Methodology	YES
6313749	30347791	A.Y.C.	CRediT	Conceptualization|Methodology|Validation|Formal analysis|Investigation|Resources|Data curation|Writing - original draft|Writing - review & editing|Supervision|Funding acquisition	Validation	Performed the experiments	Validation	YES
6313749	30347791	A.Y.C.	CRediT	Conceptualization|Methodology|Validation|Formal analysis|Investigation|Resources|Data curation|Writing - original draft|Writing - review & editing|Supervision|Funding acquisition	Formal analysis	Analyzed the data	Formal analysis	YES
6313749	30347791	A.Y.C.	CRediT	Conceptualization|Methodology|Validation|Formal analysis|Investigation|Resources|Data curation|Writing - original draft|Writing - review & editing|Supervision|Funding acquisition	Investigation	Performed the experiments	Investigation	YES
6313749	30347791	A.Y.C.	CRediT	Conceptualization|Methodology|Validation|Formal analysis|Investigation|Resources|Data curation|Writing - original draft|Writing - review & editing|Supervision|Funding acquisition	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6313749	30347791	A.Y.C.	CRediT	Conceptualization|Methodology|Validation|Formal analysis|Investigation|Resources|Data curation|Writing - original draft|Writing - review & editing|Supervision|Funding acquisition	Data curation	Analyzed the data	Data curation	YES
6313749	30347791	A.Y.C.	CRediT	Conceptualization|Methodology|Validation|Formal analysis|Investigation|Resources|Data curation|Writing - original draft|Writing - review & editing|Supervision|Funding acquisition	Writing - original draft	Wrote the paper	Writing - Original Draft	YES
6313749	30347791	A.Y.C.	CRediT	Conceptualization|Methodology|Validation|Formal analysis|Investigation|Resources|Data curation|Writing - original draft|Writing - review & editing|Supervision|Funding acquisition	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
6313749	30347791	A.Y.C.	CRediT	Conceptualization|Methodology|Validation|Formal analysis|Investigation|Resources|Data curation|Writing - original draft|Writing - review & editing|Supervision|Funding acquisition	Supervision	-	Supervision	YES
6313749	30347791	A.Y.C.	CRediT	Conceptualization|Methodology|Validation|Formal analysis|Investigation|Resources|Data curation|Writing - original draft|Writing - review & editing|Supervision|Funding acquisition	Funding acquisition	-	Funding acquisition	YES
6313749	30347791	G.F.	CRediT	Conceptualization|Investigation|Writing - review & editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6313749	30347791	G.F.	CRediT	Conceptualization|Investigation|Writing - review & editing	Investigation	Performed the experiments	Investigation	YES
6313749	30347791	G.F.	CRediT	Conceptualization|Investigation|Writing - review & editing	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
6313749	30347791	G.L.	CRediT	Methodology|Validation|Formal analysis|Investigation|Data curation|Writing - review & editing	Methodology	Performed the experiments	Methodology	YES
6313749	30347791	G.L.	CRediT	Methodology|Validation|Formal analysis|Investigation|Data curation|Writing - review & editing	Validation	Performed the experiments	Validation	YES
6313749	30347791	G.L.	CRediT	Methodology|Validation|Formal analysis|Investigation|Data curation|Writing - review & editing	Formal analysis	Analyzed the data	Formal analysis	YES
6313749	30347791	G.L.	CRediT	Methodology|Validation|Formal analysis|Investigation|Data curation|Writing - review & editing	Investigation	Performed the experiments	Investigation	YES
6313749	30347791	G.L.	CRediT	Methodology|Validation|Formal analysis|Investigation|Data curation|Writing - review & editing	Data curation	Analyzed the data	Data curation	YES
6313749	30347791	G.L.	CRediT	Methodology|Validation|Formal analysis|Investigation|Data curation|Writing - review & editing	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
6313749	30347791	G.L.S.	CRediT	Conceptualization|Methodology|Investigation|Writing - review & editing|Supervision	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6313749	30347791	G.L.S.	CRediT	Conceptualization|Methodology|Investigation|Writing - review & editing|Supervision	Methodology	Performed the experiments	Methodology	YES
6313749	30347791	G.L.S.	CRediT	Conceptualization|Methodology|Investigation|Writing - review & editing|Supervision	Investigation	Performed the experiments	Investigation	YES
6313749	30347791	G.L.S.	CRediT	Conceptualization|Methodology|Investigation|Writing - review & editing|Supervision	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
6313749	30347791	G.L.S.	CRediT	Conceptualization|Methodology|Investigation|Writing - review & editing|Supervision	Supervision	-	Supervision	YES
6313749	30347791	J.M.B.	CRediT	Conceptualization|Methodology|Validation|Formal analysis|Investigation|Resources|Data curation|Writing - review & editing|Supervision|Funding acquisition	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6313749	30347791	J.M.B.	CRediT	Conceptualization|Methodology|Validation|Formal analysis|Investigation|Resources|Data curation|Writing - review & editing|Supervision|Funding acquisition	Methodology	Performed the experiments	Methodology	YES
6313749	30347791	J.M.B.	CRediT	Conceptualization|Methodology|Validation|Formal analysis|Investigation|Resources|Data curation|Writing - review & editing|Supervision|Funding acquisition	Validation	Performed the experiments	Validation	YES
6313749	30347791	J.M.B.	CRediT	Conceptualization|Methodology|Validation|Formal analysis|Investigation|Resources|Data curation|Writing - review & editing|Supervision|Funding acquisition	Formal analysis	Analyzed the data	Formal analysis	YES
6313749	30347791	J.M.B.	CRediT	Conceptualization|Methodology|Validation|Formal analysis|Investigation|Resources|Data curation|Writing - review & editing|Supervision|Funding acquisition	Investigation	Performed the experiments	Investigation	YES
6313749	30347791	J.M.B.	CRediT	Conceptualization|Methodology|Validation|Formal analysis|Investigation|Resources|Data curation|Writing - review & editing|Supervision|Funding acquisition	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6313749	30347791	J.M.B.	CRediT	Conceptualization|Methodology|Validation|Formal analysis|Investigation|Resources|Data curation|Writing - review & editing|Supervision|Funding acquisition	Data curation	Analyzed the data	Data curation	YES
6313749	30347791	J.M.B.	CRediT	Conceptualization|Methodology|Validation|Formal analysis|Investigation|Resources|Data curation|Writing - review & editing|Supervision|Funding acquisition	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
6313749	30347791	J.M.B.	CRediT	Conceptualization|Methodology|Validation|Formal analysis|Investigation|Resources|Data curation|Writing - review & editing|Supervision|Funding acquisition	Supervision	-	Supervision	YES
6313749	30347791	J.M.B.	CRediT	Conceptualization|Methodology|Validation|Formal analysis|Investigation|Resources|Data curation|Writing - review & editing|Supervision|Funding acquisition	Funding acquisition	-	Funding acquisition	YES
6313749	30347791	J.P.	CRediT	Methodology|Validation|Investigation|Data curation|Writing - review & editing	Methodology	Performed the experiments	Methodology	YES
6313749	30347791	J.P.	CRediT	Methodology|Validation|Investigation|Data curation|Writing - review & editing	Validation	Performed the experiments	Validation	YES
6313749	30347791	J.P.	CRediT	Methodology|Validation|Investigation|Data curation|Writing - review & editing	Investigation	Performed the experiments	Investigation	YES
6313749	30347791	J.P.	CRediT	Methodology|Validation|Investigation|Data curation|Writing - review & editing	Data curation	Analyzed the data	Data curation	YES
6313749	30347791	J.P.	CRediT	Methodology|Validation|Investigation|Data curation|Writing - review & editing	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
6313749	30347791	K.M.	CRediT	Methodology|Investigation|Resources|Data curation|Writing - review & editing	Methodology	Performed the experiments	Methodology	YES
6313749	30347791	K.M.	CRediT	Methodology|Investigation|Resources|Data curation|Writing - review & editing	Investigation	Performed the experiments	Investigation	YES
6313749	30347791	K.M.	CRediT	Methodology|Investigation|Resources|Data curation|Writing - review & editing	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6313749	30347791	K.M.	CRediT	Methodology|Investigation|Resources|Data curation|Writing - review & editing	Data curation	Analyzed the data	Data curation	YES
6313749	30347791	K.M.	CRediT	Methodology|Investigation|Resources|Data curation|Writing - review & editing	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
6313749	30347791	L.E.	CRediT	Methodology|Investigation|Resources|Data curation|Writing - review & editing	Methodology	Performed the experiments	Methodology	YES
6313749	30347791	L.E.	CRediT	Methodology|Investigation|Resources|Data curation|Writing - review & editing	Investigation	Performed the experiments	Investigation	YES
6313749	30347791	L.E.	CRediT	Methodology|Investigation|Resources|Data curation|Writing - review & editing	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6313749	30347791	L.E.	CRediT	Methodology|Investigation|Resources|Data curation|Writing - review & editing	Data curation	Analyzed the data	Data curation	YES
6313749	30347791	L.E.	CRediT	Methodology|Investigation|Resources|Data curation|Writing - review & editing	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
6313749	30347791	N.P.	CRediT	Methodology|Investigation|Resources|Data curation|Writing - review & editing	Methodology	Performed the experiments	Methodology	YES
6313749	30347791	N.P.	CRediT	Methodology|Investigation|Resources|Data curation|Writing - review & editing	Investigation	Performed the experiments	Investigation	YES
6313749	30347791	N.P.	CRediT	Methodology|Investigation|Resources|Data curation|Writing - review & editing	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6313749	30347791	N.P.	CRediT	Methodology|Investigation|Resources|Data curation|Writing - review & editing	Data curation	Analyzed the data	Data curation	YES
6313749	30347791	N.P.	CRediT	Methodology|Investigation|Resources|Data curation|Writing - review & editing	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
6313749	30347791	R.L.A.	CRediT	Methodology|Validation|Formal analysis|Investigation|Data curation|Writing - original draft|Writing - review & editing	Methodology	Performed the experiments	Methodology	YES
6313749	30347791	R.L.A.	CRediT	Methodology|Validation|Formal analysis|Investigation|Data curation|Writing - original draft|Writing - review & editing	Validation	Performed the experiments	Validation	YES
6313749	30347791	R.L.A.	CRediT	Methodology|Validation|Formal analysis|Investigation|Data curation|Writing - original draft|Writing - review & editing	Formal analysis	Analyzed the data	Formal analysis	YES
6313749	30347791	R.L.A.	CRediT	Methodology|Validation|Formal analysis|Investigation|Data curation|Writing - original draft|Writing - review & editing	Investigation	Performed the experiments	Investigation	YES
6313749	30347791	R.L.A.	CRediT	Methodology|Validation|Formal analysis|Investigation|Data curation|Writing - original draft|Writing - review & editing	Data curation	Analyzed the data	Data curation	YES
6313749	30347791	R.L.A.	CRediT	Methodology|Validation|Formal analysis|Investigation|Data curation|Writing - original draft|Writing - review & editing	Writing - original draft	Wrote the paper	Writing - Original Draft	YES
6313749	30347791	R.L.A.	CRediT	Methodology|Validation|Formal analysis|Investigation|Data curation|Writing - original draft|Writing - review & editing	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
6313749	30347791	S.P.R.	CRediT	Methodology|Investigation|Resources|Data curation|Writing - review & editing	Methodology	Performed the experiments	Methodology	YES
6313749	30347791	S.P.R.	CRediT	Methodology|Investigation|Resources|Data curation|Writing - review & editing	Investigation	Performed the experiments	Investigation	YES
6313749	30347791	S.P.R.	CRediT	Methodology|Investigation|Resources|Data curation|Writing - review & editing	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6313749	30347791	S.P.R.	CRediT	Methodology|Investigation|Resources|Data curation|Writing - review & editing	Data curation	Analyzed the data	Data curation	YES
6313749	30347791	S.P.R.	CRediT	Methodology|Investigation|Resources|Data curation|Writing - review & editing	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
6313749	30347791	S.T.	CRediT	Methodology|Validation|Formal analysis|Investigation|Data curation|Writing - review & editing	Methodology	Performed the experiments	Methodology	YES
6313749	30347791	S.T.	CRediT	Methodology|Validation|Formal analysis|Investigation|Data curation|Writing - review & editing	Validation	Performed the experiments	Validation	YES
6313749	30347791	S.T.	CRediT	Methodology|Validation|Formal analysis|Investigation|Data curation|Writing - review & editing	Formal analysis	Analyzed the data	Formal analysis	YES
6313749	30347791	S.T.	CRediT	Methodology|Validation|Formal analysis|Investigation|Data curation|Writing - review & editing	Investigation	Performed the experiments	Investigation	YES
6313749	30347791	S.T.	CRediT	Methodology|Validation|Formal analysis|Investigation|Data curation|Writing - review & editing	Data curation	Analyzed the data	Data curation	YES
6313749	30347791	S.T.	CRediT	Methodology|Validation|Formal analysis|Investigation|Data curation|Writing - review & editing	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
5780666	21668677	AB	2	all collected and contributed data from their countries to the analysis	all collected and contributed data from their countries to the analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5780666	21668677	AC	2	all collected and contributed data from their countries to the analysis	all collected and contributed data from their countries to the analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5780666	21668677	AF	2	all collected and contributed data from their countries to the analysis	all collected and contributed data from their countries to the analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5780666	21668677	AO	2	all collected and contributed data from their countries to the analysis	all collected and contributed data from their countries to the analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5780666	21668677	AP	2	all collected and contributed data from their countries to the analysis	all collected and contributed data from their countries to the analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5780666	21668677	AWM	2	analysed the data and drafted the manuscript	analysed the data and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5780666	21668677	All authors	2	reviewed and edited drafts of the manuscript, and all authors read and approved the final manuscript	reviewed and edited drafts of the manuscript, and all authors read and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5780666	21668677	BA	2	all collected and contributed data from their countries to the analysis	all collected and contributed data from their countries to the analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5780666	21668677	BP	2	all collected and contributed data from their countries to the analysis	all collected and contributed data from their countries to the analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5780666	21668677	BS	2	all collected and contributed data from their countries to the analysis	all collected and contributed data from their countries to the analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5780666	21668677	CC	2	all collected and contributed data from their countries to the analysis	all collected and contributed data from their countries to the analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5780666	21668677	CG	2	all collected and contributed data from their countries to the analysis	all collected and contributed data from their countries to the analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5780666	21668677	CM	2	all collected and contributed data from their countries to the analysis|all collected and contributed data from their countries to the analysis	all collected and contributed data from their countries to the analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5780666	21668677	CM	2	all collected and contributed data from their countries to the analysis|all collected and contributed data from their countries to the analysis	all collected and contributed data from their countries to the analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5780666	21668677	DH	2	all collected and contributed data from their countries to the analysis	all collected and contributed data from their countries to the analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5780666	21668677	DN	2	all collected and contributed data from their countries to the analysis	all collected and contributed data from their countries to the analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5780666	21668677	EB	2	all collected and contributed data from their countries to the analysis	all collected and contributed data from their countries to the analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5780666	21668677	FG	2	all collected and contributed data from their countries to the analysis	all collected and contributed data from their countries to the analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5780666	21668677	GT	2	all collected and contributed data from their countries to the analysis	all collected and contributed data from their countries to the analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5780666	21668677	JM	2	all collected and contributed data from their countries to the analysis|all collected and contributed data from their countries to the analysis|drafted sections of the manuscript	all collected and contributed data from their countries to the analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5780666	21668677	JM	2	all collected and contributed data from their countries to the analysis|all collected and contributed data from their countries to the analysis|drafted sections of the manuscript	all collected and contributed data from their countries to the analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5780666	21668677	JM	2	all collected and contributed data from their countries to the analysis|all collected and contributed data from their countries to the analysis|drafted sections of the manuscript	drafted sections of the manuscript	Wrote the paper	Writing - Original Draft	YES
5780666	21668677	JT	2	all collected and contributed data from their countries to the analysis	all collected and contributed data from their countries to the analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5780666	21668677	LB	2	all collected and contributed data from their countries to the analysis	all collected and contributed data from their countries to the analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5780666	21668677	LCJ	2	all collected and contributed data from their countries to the analysis	all collected and contributed data from their countries to the analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5780666	21668677	LDL	2	all collected and contributed data from their countries to the analysis	all collected and contributed data from their countries to the analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5780666	21668677	LOC	2	all collected and contributed data from their countries to the analysis	all collected and contributed data from their countries to the analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5780666	21668677	LQ	2	all collected and contributed data from their countries to the analysis	all collected and contributed data from their countries to the analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5780666	21668677	MM	2	all collected and contributed data from their countries to the analysis	all collected and contributed data from their countries to the analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5780666	21668677	MNDF	2	all collected and contributed data from their countries to the analysis	all collected and contributed data from their countries to the analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5780666	21668677	MV	2	all collected and contributed data from their countries to the analysis	all collected and contributed data from their countries to the analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5780666	21668677	MVK	2	analysed the data and drafted the manuscript	analysed the data and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5780666	21668677	OU	2	all collected and contributed data from their countries to the analysis	all collected and contributed data from their countries to the analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5780666	21668677	PB	2	all collected and contributed data from their countries to the analysis	all collected and contributed data from their countries to the analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5780666	21668677	QSH	2	all collected and contributed data from their countries to the analysis	all collected and contributed data from their countries to the analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5780666	21668677	RF	2	all collected and contributed data from their countries to the analysis	all collected and contributed data from their countries to the analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5780666	21668677	RO	2	all collected and contributed data from their countries to the analysis	all collected and contributed data from their countries to the analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5780666	21668677	SM	2	analysed the data and drafted the manuscript	analysed the data and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5780666	21668677	VM	2	all collected and contributed data from their countries to the analysis	all collected and contributed data from their countries to the analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5780666	21668677	VS	2	all collected and contributed data from their countries to the analysis|all collected and contributed data from their countries to the analysis	all collected and contributed data from their countries to the analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5780666	21668677	VS	2	all collected and contributed data from their countries to the analysis|all collected and contributed data from their countries to the analysis	all collected and contributed data from their countries to the analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5780666	21668677	WA	2	all collected and contributed data from their countries to the analysis	all collected and contributed data from their countries to the analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
3182950	21914208	AI	2	collaborated in posing the research topic, developing the modelling strategy, parameterizing the model, and drafting the manuscript|wrote the python simulation code and managed the simulations	collaborated in posing the research topic, developing the modelling strategy, parameterizing the model, and drafting the manuscript	Performed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3182950	21914208	AI	2	collaborated in posing the research topic, developing the modelling strategy, parameterizing the model, and drafting the manuscript|wrote the python simulation code and managed the simulations	wrote the python simulation code and managed the simulations	Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Software|Writing - Original Draft	YES
3182950	21914208	ES	2	collaborated in posing the research topic, developing the modelling strategy, parameterizing the model, and drafting the manuscript	collaborated in posing the research topic, developing the modelling strategy, parameterizing the model, and drafting the manuscript	Performed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3182950	21914208	LS	2	collaborated in posing the research topic, developing the modelling strategy, parameterizing the model, and drafting the manuscript	collaborated in posing the research topic, developing the modelling strategy, parameterizing the model, and drafting the manuscript	Performed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3379942	22472190	ME	2	participated in the assay design, results discussion, and preparing the manuscript	participated in the assay design, results discussion, and preparing the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3379942	22472190	RNE	2	suggested the idea of the assay, conducted practical work and prepared the draft version of the manuscript	suggested the idea of the assay, conducted practical work and prepared the draft version of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
3379942	22472190	SM	2	participated in supervision	participated in supervision	-	Supervision	YES
4398363	25875826	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398363	25875826	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398363	25875826	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398363	25875826	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398363	25875826	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398363	25875826	RG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398363	25875826	RG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4398363	25875826	RG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4398363	25875826	RG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398363	25875826	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398363	25875826	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4398363	25875826	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4398363	25875826	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398363	25875826	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398363	25875826	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398363	25875826	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398363	25875826	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398363	25875826	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6358949	30634423	G.K.	2	contributed to the conception and design of the study|carried out the experiments|contributed to the data analysis and modeling	contributed to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6358949	30634423	G.K.	2	contributed to the conception and design of the study|carried out the experiments|contributed to the data analysis and modeling	carried out the experiments	Performed the experiments	Investigation	YES
6358949	30634423	G.K.	2	contributed to the conception and design of the study|carried out the experiments|contributed to the data analysis and modeling	contributed to the data analysis and modeling	Performed the experiments|Analyzed the data	Formal analysis|Methodology	YES
6358949	30634423	H.G.	2	contributed to the conception and design of the study|contributed to the data analysis and modeling	contributed to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6358949	30634423	H.G.	2	contributed to the conception and design of the study|contributed to the data analysis and modeling	contributed to the data analysis and modeling	Performed the experiments|Analyzed the data	Formal analysis|Methodology	YES
6358949	30634423	I.D.	2	contributed to the conception and design of the study	contributed to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6358949	30634423	K.L.	2	contributed to the conception and design of the study	contributed to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6358949	30634423	M.P.	2	contributed to the data analysis and modeling	contributed to the data analysis and modeling	Performed the experiments|Analyzed the data	Formal analysis|Methodology	YES
6358949	30634423	T.R.	2	contributed to the conception and design of the study	contributed to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6358949	30634423	all of the authors	2	contributed to the preparation of the manuscript	contributed to the preparation of the manuscript	Wrote the paper	Writing - Original Draft	YES
5432574	28559910	AQ	2	prepared some phenotypic data and prepared some tables and figures	prepared some phenotypic data and prepared some tables and figures	Performed the experiments	Investigation|Visualization	YES
5432574	28559910	DL	2	led the design and coordination of this study	led the design and coordination of this study	Conceived and designed the experiments	Methodology|Project administration	YES
5432574	28559910	FG	2	prepared genotypic data	prepared genotypic data	Performed the experiments	Investigation	YES
5432574	28559910	GY	2	prepared some phenotypic data and prepared some tables and figures	prepared some phenotypic data and prepared some tables and figures	Performed the experiments	Investigation|Visualization	YES
5432574	28559910	PZ	2	prepared phenotypic data in the field and drafted the initial manuscript	prepared phenotypic data in the field and drafted the initial manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5432574	28559910	XX	2	played a major role in planning this study and drafted some sections of the manuscript	played a major role in planning this study and drafted some sections of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5432574	28559910	YZ	2	prepared some phenotypic data and prepared some tables and figures	prepared some phenotypic data and prepared some tables and figures	Performed the experiments	Investigation|Visualization	YES
5432574	28559910	ZH	2	played a major role in planning this study and drafted some sections of the manuscript	played a major role in planning this study and drafted some sections of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5432574	28559910	ZL	2	led the design and coordination of this study	led the design and coordination of this study	Conceived and designed the experiments	Methodology|Project administration	YES
6313784	30249005	J.L.G.	2	contributed to the review and editing of this manuscript	contributed to the review and editing of this manuscript	Wrote the paper	Writing - Review & Editing	YES
6313784	30249005	M.A.B.	2	contributed to the review and editing of this manuscript|contributed to the review and editing of this manuscript	contributed to the review and editing of this manuscript	Wrote the paper	Writing - Review & Editing	YES
6313784	30249005	M.A.B.	2	contributed to the review and editing of this manuscript|contributed to the review and editing of this manuscript	contributed to the review and editing of this manuscript	Wrote the paper	Writing - Review & Editing	YES
6313784	30249005	M.M.R.	2	contributed to the review and editing of this manuscript	contributed to the review and editing of this manuscript	Wrote the paper	Writing - Review & Editing	YES
5001231	27556416	GL	2	conducted data analysis	conducted data analysis	Analyzed the data	Formal analysis	YES
5001231	27556416	GS	2	conducted data analysis	conducted data analysis	Analyzed the data	Formal analysis	YES
5001231	27556416	JZ	2	conceived of the study and collected the data|conducted data analysis|edited the manuscript	conceived of the study and collected the data	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5001231	27556416	JZ	2	conceived of the study and collected the data|conducted data analysis|edited the manuscript	conducted data analysis	Analyzed the data	Formal analysis	YES
5001231	27556416	JZ	2	conceived of the study and collected the data|conducted data analysis|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5001231	27556416	KH	2	conceived of the study and collected the data|drafted the manuscript	conceived of the study and collected the data	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5001231	27556416	KH	2	conceived of the study and collected the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5001231	27556416	ZH	2	performed the computational coding and implementation|conducted data analysis|edited the manuscript	performed the computational coding and implementation	Performed the experiments	Formal analysis|Investigation	YES
5001231	27556416	ZH	2	performed the computational coding and implementation|conducted data analysis|edited the manuscript	conducted data analysis	Analyzed the data	Formal analysis	YES
5001231	27556416	ZH	2	performed the computational coding and implementation|conducted data analysis|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
3353553	22629183	The authors	2	also declare that they all have contributed significantly to the study and that they all are in agreement with the contents of the paper	also declare that they all have contributed significantly to the study and that they all are in agreement with the contents of the paper	-	-	NO
3379952	22540963	CZC	2	produced samples, performed data analysis and data interpretation	produced samples, performed data analysis and data interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3379952	22540963	MB	2	conceived the study, participated in the design and co-ordination of the experiments and data interpretation and helped draft the manuscript	conceived the study, participated in the design and co-ordination of the experiments and data interpretation and helped draft the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Project administration|Writing - Original Draft	YES
3192699	21914207	ANA	2	participated in interpretation of data and the drafting of the manuscript	participated in interpretation of data and the drafting of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3192699	21914207	CASK	2	participated in interpretation of data and the drafting of the manuscript	participated in interpretation of data and the drafting of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3192699	21914207	GN	2	participated in the design of the trial, interpretation of data and drafting of the manuscript	participated in the design of the trial, interpretation of data and drafting of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3192699	21914207	JKT	2	participated in the design and implementation of the trial, interpretation of data and drafting of the manuscript	participated in the design and implementation of the trial, interpretation of data and drafting of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
3192699	21914207	RB	2	participated in the conception, design and implementation of the trial, statistical analysis, interpretation of data and drafting of the manuscript	participated in the conception, design and implementation of the trial, statistical analysis, interpretation of data and drafting of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
3192699	21914207	TT	2	participated in the conception and design of the trial, interpretation of data and drafting the manuscript	participated in the conception and design of the trial, interpretation of data and drafting the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
6358952	30609647	H.A.A.-G.	CRediT	Investigation|Methodology	Investigation	Performed the experiments	Investigation	YES
6358952	30609647	H.A.A.-G.	CRediT	Investigation|Methodology	Methodology	Performed the experiments	Methodology	YES
6358952	30609647	K.M.E.-S.	CRediT	Conceptualization|Investigation|Resources|Software|Supervision|Validation|Writing--review & editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6358952	30609647	K.M.E.-S.	CRediT	Conceptualization|Investigation|Resources|Software|Supervision|Validation|Writing--review & editing	Investigation	Performed the experiments	Investigation	YES
6358952	30609647	K.M.E.-S.	CRediT	Conceptualization|Investigation|Resources|Software|Supervision|Validation|Writing--review & editing	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6358952	30609647	K.M.E.-S.	CRediT	Conceptualization|Investigation|Resources|Software|Supervision|Validation|Writing--review & editing	Software	Contributed reagents/materials/analysis tools	Software	YES
6358952	30609647	K.M.E.-S.	CRediT	Conceptualization|Investigation|Resources|Software|Supervision|Validation|Writing--review & editing	Supervision	-	Supervision	YES
6358952	30609647	K.M.E.-S.	CRediT	Conceptualization|Investigation|Resources|Software|Supervision|Validation|Writing--review & editing	Validation	Performed the experiments	Validation	YES
6358952	30609647	K.M.E.-S.	CRediT	Conceptualization|Investigation|Resources|Software|Supervision|Validation|Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6358952	30609647	N.A.A.	CRediT	Data curation|Investigation|Supervision	Data curation	Analyzed the data	Data curation	YES
6358952	30609647	N.A.A.	CRediT	Data curation|Investigation|Supervision	Investigation	Performed the experiments	Investigation	YES
6358952	30609647	N.A.A.	CRediT	Data curation|Investigation|Supervision	Supervision	-	Supervision	YES
6358952	30609647	O.A.A.	CRediT	Data curation|Investigation|Supervision|Writing--original draft	Data curation	Analyzed the data	Data curation	YES
6358952	30609647	O.A.A.	CRediT	Data curation|Investigation|Supervision|Writing--original draft	Investigation	Performed the experiments	Investigation	YES
6358952	30609647	O.A.A.	CRediT	Data curation|Investigation|Supervision|Writing--original draft	Supervision	-	Supervision	YES
6358952	30609647	O.A.A.	CRediT	Data curation|Investigation|Supervision|Writing--original draft	Writing--original draft	Wrote the paper	Writing - Original Draft	YES
6358952	30609647	U.A.F.	CRediT	Data curation|Methodology	Data curation	Analyzed the data	Data curation	YES
6358952	30609647	U.A.F.	CRediT	Data curation|Methodology	Methodology	Performed the experiments	Methodology	YES
4398365	25874633	FQ	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398365	25874633	JHQ	PLoS5	Conceived and designed the experiments|Designed and revised the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398365	25874633	JHQ	PLoS5	Conceived and designed the experiments|Designed and revised the paper	Designed and revised the paper	Conceived and designed the experiments|Wrote the paper	Writing - Review & Editing	YES
4398365	25874633	JW	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398365	25874633	WJM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398365	25874633	XC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398365	25874633	XC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398365	25874633	XC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398365	25874633	XDC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4398365	25874633	XDC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398365	25874633	XW	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398365	25874633	XW	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398365	25874633	XXT	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4398365	25874633	XXT	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398365	25874633	YL	PLoS5	Analyzed the data|Wrote the paper|Designed and revised the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398365	25874633	YL	PLoS5	Analyzed the data|Wrote the paper|Designed and revised the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398365	25874633	YL	PLoS5	Analyzed the data|Wrote the paper|Designed and revised the paper	Designed and revised the paper	Conceived and designed the experiments|Wrote the paper	Writing - Review & Editing	YES
4398365	25874633	YLS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4398365	25874633	YLS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398365	25874633	ZJD	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398365	25874633	ZJD	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398365	25874633	ZJD	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5432576	28559909	All the authors	2	have revised this manuscript critically before the submission and agreed with all aspects of the work	have revised this manuscript critically before the submission and agreed with all aspects of the work	Wrote the paper	Writing - Review & Editing	YES
5432576	28559909	JC	2	carried out the experiment and participated in data analysis	carried out the experiment and participated in data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5432576	28559909	ML	2	carried out the experiment and participated in data analysis	carried out the experiment and participated in data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5432576	28559909	SL	2	designed the experiment, analyzed the data, and drafted the manuscript	designed the experiment, analyzed the data, and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5432576	28559909	ZG	2	designed the experiment, analyzed the data, and drafted the manuscript	designed the experiment, analyzed the data, and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3386892	22490336	CP	2	carried out recombinant protein expression and biochemical characterizations	carried out recombinant protein expression and biochemical characterizations	Performed the experiments	Investigation	YES
3386892	22490336	KW	2	performed large scale protein expression and purification	performed large scale protein expression and purification	Performed the experiments	Investigation	YES
3386892	22490336	NR	2	carried out recombinant protein expression and biochemical characterizations	carried out recombinant protein expression and biochemical characterizations	Performed the experiments	Investigation	YES
3386892	22490336	TB	2	performed large scale protein expression and purification	performed large scale protein expression and purification	Performed the experiments	Investigation	YES
3386892	22490336	YP	2	carried out plasmid construction	carried out plasmid construction	Performed the experiments	Investigation	YES
3386892	22490336	ZW	2	carried out plasmid construction	carried out plasmid construction	Performed the experiments	Investigation	YES
5001232	27535545	AS	2	designed the evolutionary algorithm and the path computation techniques and designed the experiments|wrote the manuscript|edited the final version	designed the evolutionary algorithm and the path computation techniques and designed the experiments	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Formal analysis|Methodology|Software	YES
5001232	27535545	AS	2	designed the evolutionary algorithm and the path computation techniques and designed the experiments|wrote the manuscript|edited the final version	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5001232	27535545	AS	2	designed the evolutionary algorithm and the path computation techniques and designed the experiments|wrote the manuscript|edited the final version	edited the final version	Wrote the paper	Writing - Review & Editing	YES
5001232	27535545	DC	2	designed and implemented the visual statistical analysis|wrote the manuscript	designed and implemented the visual statistical analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
5001232	27535545	DC	2	designed and implemented the visual statistical analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5001232	27535545	ES	2	designed the evolutionary algorithm and the path computation techniques and designed the experiments|implemented the evolutionary algorithm and the path computation techniques|wrote the manuscript	designed the evolutionary algorithm and the path computation techniques and designed the experiments	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Formal analysis|Methodology|Software	YES
5001232	27535545	ES	2	designed the evolutionary algorithm and the path computation techniques and designed the experiments|implemented the evolutionary algorithm and the path computation techniques|wrote the manuscript	implemented the evolutionary algorithm and the path computation techniques	Performed the experiments|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Software	YES
5001232	27535545	ES	2	designed the evolutionary algorithm and the path computation techniques and designed the experiments|implemented the evolutionary algorithm and the path computation techniques|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5001232	27535545	KD	2	designed the evolutionary algorithm and the path computation techniques and designed the experiments|wrote the manuscript|edited the final version	designed the evolutionary algorithm and the path computation techniques and designed the experiments	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Formal analysis|Methodology|Software	YES
5001232	27535545	KD	2	designed the evolutionary algorithm and the path computation techniques and designed the experiments|wrote the manuscript|edited the final version	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5001232	27535545	KD	2	designed the evolutionary algorithm and the path computation techniques and designed the experiments|wrote the manuscript|edited the final version	edited the final version	Wrote the paper	Writing - Review & Editing	YES
3192700	21936945	DS	7	Design of the study, data analysis	Design of the study, data analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
3192700	21936945	ES	7	Design of the study	Design of the study	Conceived and designed the experiments	Methodology	YES
3192700	21936945	JF	7	Molecular virology laboratory assistance	Molecular virology laboratory assistance	Performed the experiments	Investigation	YES
3192700	21936945	LI	7	Design of the study	Design of the study	Conceived and designed the experiments	Methodology	YES
3192700	21936945	MS	7	Molecular virology laboratory assistance, data analysis	Molecular virology laboratory assistance, data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3192700	21936945	RB	7	Virology laboratory assistance	Virology laboratory assistance	-	-	NO
3192700	21936945	RD	7	Design of the study, Manuscript preparation	Design of the study, Manuscript preparation	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4398366	25874625	CHY	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4398366	25874625	KCT	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4398366	25874625	KCT	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398366	25874625	LHY	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398366	25874625	YCC	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398366	25874625	YCC	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398366	25874625	YCC	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398366	25874625	YCC	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398366	25874625	YLH	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398366	25874625	YLH	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5518762	28781572	A.G.	PLoS52	analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
5518762	28781572	G.K.	PLoS52	conceived the ideas|analysed the data|led the writing of the manuscript	conceived the ideas	Conceived and designed the experiments	Conceptualization	YES
5518762	28781572	G.K.	PLoS52	conceived the ideas|analysed the data|led the writing of the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
5518762	28781572	G.K.	PLoS52	conceived the ideas|analysed the data|led the writing of the manuscript	led the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5518762	28781572	I.D.	PLoS52	contributed to the analyses	contributed to the analyses	Analyzed the data	Formal analysis	YES
5518762	28781572	J.W.	PLoS52	contributed to the analyses	contributed to the analyses	Analyzed the data	Formal analysis	YES
5518762	28781572	S.D.	PLoS52	conceived the ideas|led the writing of the manuscript	conceived the ideas	Conceived and designed the experiments	Conceptualization	YES
5518762	28781572	S.D.	PLoS52	conceived the ideas|led the writing of the manuscript	led the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5518762	28781572	all authors	PLoS52	contributed to the discussion of ideas and revised the text	contributed to the discussion of ideas and revised the text	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
5432612	28559911	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5432612	28559911	CY	2	analyzed and interpreted the data	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5432612	28559911	HW	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5432612	28559911	LH	2	performed experiments|analyzed and interpreted the data|wrote the manuscript	performed experiments	Performed the experiments	Investigation	YES
5432612	28559911	LH	2	performed experiments|analyzed and interpreted the data|wrote the manuscript	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5432612	28559911	LH	2	performed experiments|analyzed and interpreted the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5432612	28559911	SJ	2	collected materials	collected materials	Performed the experiments	Investigation	YES
5432612	28559911	SS	2	collected materials	collected materials	Performed the experiments	Investigation	YES
5432612	28559911	WG	2	performed experiments|analyzed and interpreted the data|wrote the manuscript	performed experiments	Performed the experiments	Investigation	YES
5432612	28559911	WG	2	performed experiments|analyzed and interpreted the data|wrote the manuscript	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5432612	28559911	WG	2	performed experiments|analyzed and interpreted the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5432612	28559911	XS	2	collected materials	collected materials	Performed the experiments	Investigation	YES
5432612	28559911	YH	2	designed the study|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5432612	28559911	YH	2	designed the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5432612	28559911	ZZ	2	analyzed and interpreted the data	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
6358969	30602683	A.M.N.D.	PLoS52	performed the synthesis and structural characterization of magnetic/plasmonic nanoparticles, liposomes, and magnetoliposomes, and the photo physical studies	performed the synthesis and structural characterization of magnetic/plasmonic nanoparticles, liposomes, and magnetoliposomes, and the photo physical studies	Performed the experiments	Investigation	YES
6358969	30602683	A.M.P.	PLoS52	performed the experimental magnetic measurements|performed the analysis of the magnetic properties and the corresponding discussion	performed the experimental magnetic measurements	Performed the experiments	Investigation	YES
6358969	30602683	A.M.P.	PLoS52	performed the experimental magnetic measurements|performed the analysis of the magnetic properties and the corresponding discussion	performed the analysis of the magnetic properties and the corresponding discussion	Performed the experiments	Investigation	YES
6358969	30602683	A.P.	PLoS52	performed the experimental magnetic measurements	performed the experimental magnetic measurements	Performed the experiments	Investigation	YES
6358969	30602683	A.R.O.R.	PLoS52	performed the synthesis and structural characterization of magnetic/plasmonic nanoparticles, liposomes, and magnetoliposomes, and the photo physical studies|participated in the draft of the manuscript	performed the synthesis and structural characterization of magnetic/plasmonic nanoparticles, liposomes, and magnetoliposomes, and the photo physical studies	Performed the experiments	Investigation	YES
6358969	30602683	A.R.O.R.	PLoS52	performed the synthesis and structural characterization of magnetic/plasmonic nanoparticles, liposomes, and magnetoliposomes, and the photo physical studies|participated in the draft of the manuscript	participated in the draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
6358969	30602683	All the authors	PLoS52	revised and approved the manuscript	revised and approved the manuscript	Wrote the paper	Writing - Review & Editing	YES
6358969	30602683	B.G.A.	PLoS52	performed the analysis of the magnetic properties and the corresponding discussion	performed the analysis of the magnetic properties and the corresponding discussion	Performed the experiments	Investigation	YES
6358969	30602683	E.M.S.C.	PLoS52	conceived and designed the experiments|supervised the photo physical measurements and the interpretation of the results|participated in the draft of the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6358969	30602683	E.M.S.C.	PLoS52	conceived and designed the experiments|supervised the photo physical measurements and the interpretation of the results|participated in the draft of the manuscript	supervised the photo physical measurements and the interpretation of the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Supervision	YES
6358969	30602683	E.M.S.C.	PLoS52	conceived and designed the experiments|supervised the photo physical measurements and the interpretation of the results|participated in the draft of the manuscript	participated in the draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
6358969	30602683	J.O.G.M.	PLoS52	performed the synthesis and structural characterization of magnetic/plasmonic nanoparticles, liposomes, and magnetoliposomes, and the photo physical studies	performed the synthesis and structural characterization of magnetic/plasmonic nanoparticles, liposomes, and magnetoliposomes, and the photo physical studies	Performed the experiments	Investigation	YES
6358969	30602683	J.P.A.	PLoS52	performed the experimental magnetic measurements	performed the experimental magnetic measurements	Performed the experiments	Investigation	YES
6358969	30602683	M.J.R.P.Q.	PLoS52	synthesized the anti-tumor compound and contributed to the interpretation of the results	synthesized the anti-tumor compound and contributed to the interpretation of the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6358969	30602683	P.J.G.C.	PLoS52	conceived and designed the experiments|supervised the structural characterization and analysis of the results|wrote the final manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6358969	30602683	P.J.G.C.	PLoS52	conceived and designed the experiments|supervised the structural characterization and analysis of the results|wrote the final manuscript	supervised the structural characterization and analysis of the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Supervision	YES
6358969	30602683	P.J.G.C.	PLoS52	conceived and designed the experiments|supervised the structural characterization and analysis of the results|wrote the final manuscript	wrote the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3556092	23256754	All authors	2	participated on drafting of the manuscript	participated on drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
3556092	23256754	JH	2	carried out the in vitro cytotoxicity experiments on thp-1 cells and in vitro anti-inflammatory assays	carried out the in vitro cytotoxicity experiments on thp-1 cells and in vitro anti-inflammatory assays	Performed the experiments	Investigation	YES
3556092	23256754	JV	2	carried out the interaction studies with sulfur-containing biomolecules	carried out the interaction studies with sulfur-containing biomolecules	Performed the experiments	Investigation	YES
3556092	23256754	RB	2	prepared the tested compounds in sufficient quantities	prepared the tested compounds in sufficient quantities	Performed the experiments	Investigation	YES
3556092	23256754	ZD	2	carried out the in vitro cytotoxicity experiments and experiments involving the human hepatocytes	carried out the in vitro cytotoxicity experiments and experiments involving the human hepatocytes	Performed the experiments	Investigation	YES
3556092	23256754	ZT	2	provided critical results evaluation and coordinated all works, contributed to the manuscript preparation, including the final approval of the manuscript before submitting	provided critical results evaluation and coordinated all works, contributed to the manuscript preparation, including the final approval of the manuscript before submitting	Wrote the paper	Project administration|Writing - Original Draft	YES
3194147	21967783	ADH	2	conceived the idea of this study and designed the tool to be used|reviewed extensively	conceived the idea of this study and designed the tool to be used	Conceived and designed the experiments	Conceptualization|Methodology	YES
3194147	21967783	ADH	2	conceived the idea of this study and designed the tool to be used|reviewed extensively	reviewed extensively	-	-	NO
3194147	21967783	PIF	2	reviewed the manuscript critically	reviewed the manuscript critically	Wrote the paper	Writing - Review & Editing	YES
3194147	21967783	RAD	2	conceived the idea of this study and designed the tool to be used	conceived the idea of this study and designed the tool to be used	Conceived and designed the experiments	Conceptualization|Methodology	YES
3194147	21967783	SM	2	reviewed the manuscript critically	reviewed the manuscript critically	Wrote the paper	Writing - Review & Editing	YES
3194147	21967783	ZEH	2	reviewed the manuscript critically	reviewed the manuscript critically	Wrote the paper	Writing - Review & Editing	YES
5780670	21668662	A Amendola	1	Study concept and design|Analysis and interpretation of data|Critical revision of the manuscript for important intellectual content	Study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5780670	21668662	A Amendola	1	Study concept and design|Analysis and interpretation of data|Critical revision of the manuscript for important intellectual content	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
5780670	21668662	A Amendola	1	Study concept and design|Analysis and interpretation of data|Critical revision of the manuscript for important intellectual content	Critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5780670	21668662	A Zappa	1	Analysis and interpretation of data|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content|Statistical analysis	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
5780670	21668662	A Zappa	1	Analysis and interpretation of data|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content|Statistical analysis	Drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
5780670	21668662	A Zappa	1	Analysis and interpretation of data|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content|Statistical analysis	Critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5780670	21668662	A Zappa	1	Analysis and interpretation of data|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content|Statistical analysis	Statistical analysis	Analyzed the data	Formal analysis	YES
5780670	21668662	D Dilillo	1	Acquisition of data|Critical revision of the manuscript for important intellectual content	Acquisition of data	Performed the experiments	Investigation	YES
5780670	21668662	D Dilillo	1	Acquisition of data|Critical revision of the manuscript for important intellectual content	Critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5780670	21668662	E Galli	1	Acquisition of data|Analysis and interpretation of data|Drafting of the manuscript|Statistical analysis	Acquisition of data	Performed the experiments	Investigation	YES
5780670	21668662	E Galli	1	Acquisition of data|Analysis and interpretation of data|Drafting of the manuscript|Statistical analysis	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
5780670	21668662	E Galli	1	Acquisition of data|Analysis and interpretation of data|Drafting of the manuscript|Statistical analysis	Drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
5780670	21668662	E Galli	1	Acquisition of data|Analysis and interpretation of data|Drafting of the manuscript|Statistical analysis	Statistical analysis	Analyzed the data	Formal analysis	YES
5780670	21668662	E Pariani	1	Analysis and interpretation of data	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
5780670	21668662	E Riva	1	Study concept and design|Final approval of the version to be published	Study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5780670	21668662	E Riva	1	Study concept and design|Final approval of the version to be published	Final approval of the version to be published	-	-	NO
5780670	21668662	E Tanzi	1	Study concept and design|Final approval of the version to be published	Study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5780670	21668662	E Tanzi	1	Study concept and design|Final approval of the version to be published	Final approval of the version to be published	-	-	NO
5780670	21668662	F Salvini	1	Acquisition of data	Acquisition of data	Performed the experiments	Investigation	YES
5780670	21668662	G Zuccotti	1	Study concept and design|Final approval of the version to be published	Study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5780670	21668662	G Zuccotti	1	Study concept and design|Final approval of the version to be published	Final approval of the version to be published	-	-	NO
5780670	21668662	M Giovannini	1	Study concept and design|Final approval of the version to be published	Study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5780670	21668662	M Giovannini	1	Study concept and design|Final approval of the version to be published	Final approval of the version to be published	-	-	NO
5780670	21668662	M Martinelli	1	Analysis and interpretation of data|Statistical analysis	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
5780670	21668662	M Martinelli	1	Analysis and interpretation of data|Statistical analysis	Statistical analysis	Analyzed the data	Formal analysis	YES
4398367	25875843	AB	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398367	25875843	AB	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398367	25875843	AJ	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398367	25875843	AJ	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398367	25875843	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398367	25875843	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398367	25875843	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398367	25875843	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398367	25875843	BK	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398367	25875843	BM	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398367	25875843	BM	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398367	25875843	BW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398367	25875843	BW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398367	25875843	CG	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398367	25875843	CG	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398367	25875843	CM	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398367	25875843	CM	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398367	25875843	CN	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398367	25875843	CN	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398367	25875843	CN	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398367	25875843	EL	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398367	25875843	EL	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398367	25875843	ES	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398367	25875843	ES	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398367	25875843	FG	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398367	25875843	FG	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398367	25875843	FM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398367	25875843	FM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398367	25875843	FM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398367	25875843	FM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398367	25875843	GB	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398367	25875843	GB	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398367	25875843	GB	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398367	25875843	KGR	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398367	25875843	KGR	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398367	25875843	LM	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398367	25875843	LM	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398367	25875843	LP	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398367	25875843	LP	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398367	25875843	M. Marovich	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398367	25875843	M. Marovich	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398367	25875843	M. Missanga	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398367	25875843	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398367	25875843	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398367	25875843	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398367	25875843	MH	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398367	25875843	MH	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398367	25875843	MR	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398367	25875843	MR	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398367	25875843	PJM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398367	25875843	PJM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398367	25875843	PJM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398367	25875843	PM	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398367	25875843	PM	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398367	25875843	RS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398367	25875843	RS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398367	25875843	S. Cormack	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398367	25875843	S. Mfinanga	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398367	25875843	SA	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398367	25875843	SA	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398367	25875843	SA	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398367	25875843	WS	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398367	25875843	WS	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5001233	27556805	BD	2	wrote the software code, ran the pipeline, and provided the human data results	wrote the software code, ran the pipeline, and provided the human data results	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Data curation|Investigation|Resources|Software|Writing - Original Draft	YES
5001233	27556805	JK	2	wrote the software code, performed the analysis, and wrote the manuscript	wrote the software code, performed the analysis, and wrote the manuscript	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Software|Writing - Original Draft	YES
5001233	27556805	JRH	2	performed the experiments and provided biological interpretation	performed the experiments and provided biological interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5001233	27556805	RJK	2	designed the experiments and wrote the manuscript	designed the experiments and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5001233	27556805	RSR	2	other tools	other tools	-	-	NO
5001233	27556805	YB	2	designed and supervised the project, performed the analysis, provided biological interpretation, and wrote the manuscript	designed and supervised the project, performed the analysis, provided biological interpretation, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Supervision|Writing - Original Draft	YES
3750111	21999701	GU	2	conceived of the study and participated in its design and coordination	conceived of the study and participated in its design and coordination	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
3750111	21999701	NT	2	carried out the synthesis and characterization of the compounds	carried out the synthesis and characterization of the compounds	Performed the experiments	Investigation	YES
3750111	21999701	NV	2	performed the calculations of molecular descriptors and the statistical analysis	performed the calculations of molecular descriptors and the statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5432617	28559905	CW	2	were performed the sample collection, analyzed the data and wrote the manuscript	were performed the sample collection, analyzed the data and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5432617	28559905	JL	2	designed the project and revised the manuscript	designed the project and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5432617	28559905	LT	2	were performed the sample collection, analyzed the data and wrote the manuscript	were performed the sample collection, analyzed the data and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5432617	28559905	WQ	2	were performed the sample collection, analyzed the data and wrote the manuscript	were performed the sample collection, analyzed the data and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5432617	28559905	WZ	2	were performed the sample collection, analyzed the data and wrote the manuscript	were performed the sample collection, analyzed the data and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5432617	28559905	XH	2	were performed the sample collection, analyzed the data and wrote the manuscript	were performed the sample collection, analyzed the data and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5432617	28559905	XZ	2	designed the project and revised the manuscript	designed the project and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
6358973	30621127	A.M.F.	CRediT	writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6358973	30621127	C.C.	CRediT	formal analysis|writing--review and editing	formal analysis	Analyzed the data	Formal analysis	YES
6358973	30621127	C.C.	CRediT	formal analysis|writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6358973	30621127	E.E.-F.	CRediT	formal analysis	formal analysis	Analyzed the data	Formal analysis	YES
6358973	30621127	I.U.	CRediT	investigation	investigation	Performed the experiments	Investigation	YES
6358973	30621127	J.E.P.	CRediT	investigation	investigation	Performed the experiments	Investigation	YES
6358973	30621127	M.L.M.	CRediT	writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6358973	30621127	M.M.	CRediT	supervision	supervision	-	Supervision	YES
6358973	30621127	M.R.	CRediT	Writing--original draft preparation|investigation	Writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6358973	30621127	M.R.	CRediT	Writing--original draft preparation|investigation	investigation	Performed the experiments	Investigation	YES
6358973	30621127	O.D.-S.	CRediT	formal analysis	formal analysis	Analyzed the data	Formal analysis	YES
3194148	21967809	ES	2	assisted with country-specific data collection	assisted with country-specific data collection	Performed the experiments	Investigation	YES
3194148	21967809	FR	2	conceptualized the study and wrote a first draft, which was edited by all authors|finalized the manuscript	conceptualized the study and wrote a first draft, which was edited by all authors	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
3194148	21967809	FR	2	conceptualized the study and wrote a first draft, which was edited by all authors|finalized the manuscript	finalized the manuscript	Wrote the paper	Writing - Review & Editing	YES
3194148	21967809	MP	2	checked scientific soundness and reviewed the manuscript several times|finalized the manuscript	checked scientific soundness and reviewed the manuscript several times	Wrote the paper	Writing - Review & Editing	YES
3194148	21967809	MP	2	checked scientific soundness and reviewed the manuscript several times|finalized the manuscript	finalized the manuscript	Wrote the paper	Writing - Review & Editing	YES
3194148	21967809	MPP	2	checked scientific soundness and reviewed the manuscript several times	checked scientific soundness and reviewed the manuscript several times	Wrote the paper	Writing - Review & Editing	YES
3194148	21967809	WVD	2	checked scientific soundness and reviewed the manuscript several times	checked scientific soundness and reviewed the manuscript several times	Wrote the paper	Writing - Review & Editing	YES
3194148	21967809	YA	2	assisted with country-specific data collection	assisted with country-specific data collection	Performed the experiments	Investigation	YES
6358979	30577564	E.K.K.	CRediT	methodology	methodology	Performed the experiments	Methodology	YES
6358979	30577564	H.C.K.	CRediT	methodology	methodology	Performed the experiments	Methodology	YES
6358979	30577564	H.K.	CRediT	writing-original draft preparation	writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
6358979	30577564	H.L.	CRediT	methodology	methodology	Performed the experiments	Methodology	YES
6358979	30577564	J.L.	CRediT	Conceptualization|writing-original draft preparation|funding acquisition|supervision	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6358979	30577564	J.L.	CRediT	Conceptualization|writing-original draft preparation|funding acquisition|supervision	writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
6358979	30577564	J.L.	CRediT	Conceptualization|writing-original draft preparation|funding acquisition|supervision	funding acquisition	-	Funding acquisition	YES
6358979	30577564	J.L.	CRediT	Conceptualization|writing-original draft preparation|funding acquisition|supervision	supervision	-	Supervision	YES
6358979	30577564	J.M.C.	CRediT	Conceptualization|methodology|writing-original draft preparation	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6358979	30577564	J.M.C.	CRediT	Conceptualization|methodology|writing-original draft preparation	methodology	Performed the experiments	Methodology	YES
6358979	30577564	J.M.C.	CRediT	Conceptualization|methodology|writing-original draft preparation	writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
6358979	30577564	K.J.	CRediT	Conceptualization|methodology|writing-original draft preparation	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6358979	30577564	K.J.	CRediT	Conceptualization|methodology|writing-original draft preparation	methodology	Performed the experiments	Methodology	YES
6358979	30577564	K.J.	CRediT	Conceptualization|methodology|writing-original draft preparation	writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
4398368	25874364	DG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398368	25874364	DG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398368	25874364	DG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398368	25874364	DG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398368	25874364	DG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398368	25874364	RF	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398368	25874364	RF	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398368	25874364	RF	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398368	25874364	RM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398368	25874364	RM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398368	25874364	RM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398368	25874364	RM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398368	25874364	RM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398368	25874364	TROF	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398368	25874364	TROF	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398368	25874364	TROF	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3194149	21967844	ABS	2	wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
3194149	21967844	AJ	2	wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
3194149	21967844	All authors	2	were involved in the revision of the manuscript and approved the document for publication	were involved in the revision of the manuscript and approved the document for publication	Wrote the paper	Writing - Review & Editing	YES
3194149	21967844	EJS	2	wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
5001234	27557423	All authors	2	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5001234	27557423	PX	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5001234	27557423	SP	2	conceived the study|analyzed the results and wrote the paper	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5001234	27557423	SP	2	conceived the study|analyzed the results and wrote the paper	analyzed the results and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5001234	27557423	SR	2	conceived the study|analyzed the results and wrote the paper	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5001234	27557423	SR	2	conceived the study|analyzed the results and wrote the paper	analyzed the results and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4396140	25918724	Aileen I. Tsai	2	contributed equally to cocorrespondence	contributed equally to cocorrespondence	-	-	NO
4396140	25918724	Tzung-Hai Yen	2	contributed equally to cocorrespondence	contributed equally to cocorrespondence	-	-	NO
6358986	30669623	A.A.	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
6358986	30669623	A.P.	2	wrote the main manuscript text	wrote the main manuscript text	Wrote the paper	Writing - Original Draft	YES
6358986	30669623	A.T.B.	2	prepared figures	prepared figures	-	Visualization	YES
6358986	30669623	C.C.	2	prepared figures|revised the manuscript	prepared figures	-	Visualization	YES
6358986	30669623	C.C.	2	prepared figures|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
6358986	30669623	E.P.	2	prepared figures	prepared figures	-	Visualization	YES
6358986	30669623	G.A.	2	prepared figures	prepared figures	-	Visualization	YES
6358986	30669623	G.B.	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
6358986	30669623	H.E.M.	2	wrote the main manuscript text	wrote the main manuscript text	Wrote the paper	Writing - Original Draft	YES
6358986	30669623	P.C.	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
6358986	30669623	V.C.	2	prepared figures	prepared figures	-	Visualization	YES
3194150	21967874	CL	2	were involved in revising the manuscript for important intellectual content	were involved in revising the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
3194150	21967874	DS	2	was involved in drafting the manuscript	was involved in drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
3194150	21967874	HG	2	were involved in revising the manuscript for important intellectual content	were involved in revising the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4398369	25874612	AC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398369	25874612	AC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398369	25874612	AC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398369	25874612	AC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398369	25874612	CC	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4398369	25874612	CG	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398369	25874612	CG	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398369	25874612	FDC	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4398369	25874612	GP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398369	25874612	MB	PLoS5	Performed the experiments|Wrote the paper|Statistical analysis	Performed the experiments	Performed the experiments	Investigation	YES
4398369	25874612	MB	PLoS5	Performed the experiments|Wrote the paper|Statistical analysis	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398369	25874612	MB	PLoS5	Performed the experiments|Wrote the paper|Statistical analysis	Statistical analysis	Analyzed the data	Formal analysis	YES
4398369	25874612	MCA	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4398369	25874612	MCM	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4398369	25874612	MP	PLoS5	Performed the experiments|Wrote the paper|Statistical analysis	Performed the experiments	Performed the experiments	Investigation	YES
4398369	25874612	MP	PLoS5	Performed the experiments|Wrote the paper|Statistical analysis	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398369	25874612	MP	PLoS5	Performed the experiments|Wrote the paper|Statistical analysis	Statistical analysis	Analyzed the data	Formal analysis	YES
4398369	25874612	SM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398369	25874612	SR	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5432621	28559906	CC	2	took part in the experimental work	took part in the experimental work	Performed the experiments	Investigation	YES
5432621	28559906	CK	2	contributed to the project design|performed the statistical and bioinformatic analyses|were involved in data interpretation	contributed to the project design	Conceived and designed the experiments	Methodology	YES
5432621	28559906	CK	2	contributed to the project design|performed the statistical and bioinformatic analyses|were involved in data interpretation	performed the statistical and bioinformatic analyses	Analyzed the data	Formal analysis	YES
5432621	28559906	CK	2	contributed to the project design|performed the statistical and bioinformatic analyses|were involved in data interpretation	were involved in data interpretation	Analyzed the data	Formal analysis	YES
5432621	28559906	FE	2	contributed to the project design|took part in the experimental work	contributed to the project design	Conceived and designed the experiments	Methodology	YES
5432621	28559906	FE	2	contributed to the project design|took part in the experimental work	took part in the experimental work	Performed the experiments	Investigation	YES
5432621	28559906	JB	2	contributed to the project design|took part in the experimental work	contributed to the project design	Conceived and designed the experiments	Methodology	YES
5432621	28559906	JB	2	contributed to the project design|took part in the experimental work	took part in the experimental work	Performed the experiments	Investigation	YES
5432621	28559906	LC	2	contributed to the project design|took part in the experimental work|performed the statistical and bioinformatic analyses|were involved in data interpretation|wrote the manuscript	contributed to the project design	Conceived and designed the experiments	Methodology	YES
5432621	28559906	LC	2	contributed to the project design|took part in the experimental work|performed the statistical and bioinformatic analyses|were involved in data interpretation|wrote the manuscript	took part in the experimental work	Performed the experiments	Investigation	YES
5432621	28559906	LC	2	contributed to the project design|took part in the experimental work|performed the statistical and bioinformatic analyses|were involved in data interpretation|wrote the manuscript	performed the statistical and bioinformatic analyses	Analyzed the data	Formal analysis	YES
5432621	28559906	LC	2	contributed to the project design|took part in the experimental work|performed the statistical and bioinformatic analyses|were involved in data interpretation|wrote the manuscript	were involved in data interpretation	Analyzed the data	Formal analysis	YES
5432621	28559906	LC	2	contributed to the project design|took part in the experimental work|performed the statistical and bioinformatic analyses|were involved in data interpretation|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5432621	28559906	MG	2	contributed to the project design	contributed to the project design	Conceived and designed the experiments	Methodology	YES
5432621	28559906	MM	2	performed the statistical and bioinformatic analyses	performed the statistical and bioinformatic analyses	Analyzed the data	Formal analysis	YES
5432621	28559906	MS	2	took part in the experimental work	took part in the experimental work	Performed the experiments	Investigation	YES
5432621	28559906	MT	2	took part in the experimental work	took part in the experimental work	Performed the experiments	Investigation	YES
5432621	28559906	RL	2	provided the metabolic analysis	provided the metabolic analysis	-	-	NO
5432621	28559906	SD	2	contributed to the project design	contributed to the project design	Conceived and designed the experiments	Methodology	YES
6359009	30646534	A.R.-D.	CRediT	methodology	methodology	Performed the experiments	Methodology	YES
6359009	30646534	D.D.-G.	CRediT	methodology|investigation|writing--original draft preparation|writing--review and editing	methodology	Performed the experiments	Methodology	YES
6359009	30646534	D.D.-G.	CRediT	methodology|investigation|writing--original draft preparation|writing--review and editing	investigation	Performed the experiments	Investigation	YES
6359009	30646534	D.D.-G.	CRediT	methodology|investigation|writing--original draft preparation|writing--review and editing	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6359009	30646534	D.D.-G.	CRediT	methodology|investigation|writing--original draft preparation|writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6359009	30646534	P.L.P.	CRediT	Conceptualization|resources|writing--original draft preparation|writing--review and editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6359009	30646534	P.L.P.	CRediT	Conceptualization|resources|writing--original draft preparation|writing--review and editing	resources	Contributed reagents/materials/analysis tools	Resources	YES
6359009	30646534	P.L.P.	CRediT	Conceptualization|resources|writing--original draft preparation|writing--review and editing	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6359009	30646534	P.L.P.	CRediT	Conceptualization|resources|writing--original draft preparation|writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6359009	30646534	P.R.A.	CRediT	methodology|investigation|writing--original draft preparation|writing--review and editing	methodology	Performed the experiments	Methodology	YES
6359009	30646534	P.R.A.	CRediT	methodology|investigation|writing--original draft preparation|writing--review and editing	investigation	Performed the experiments	Investigation	YES
6359009	30646534	P.R.A.	CRediT	methodology|investigation|writing--original draft preparation|writing--review and editing	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6359009	30646534	P.R.A.	CRediT	methodology|investigation|writing--original draft preparation|writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6359009	30646534	S.G.-R.	CRediT	Conceptualization|resources|writing--original draft preparation|writing--review and editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6359009	30646534	S.G.-R.	CRediT	Conceptualization|resources|writing--original draft preparation|writing--review and editing	resources	Contributed reagents/materials/analysis tools	Resources	YES
6359009	30646534	S.G.-R.	CRediT	Conceptualization|resources|writing--original draft preparation|writing--review and editing	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6359009	30646534	S.G.-R.	CRediT	Conceptualization|resources|writing--original draft preparation|writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6359009	30646534	S.P.	CRediT	writing--original draft preparation|writing--review and editing	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6359009	30646534	S.P.	CRediT	writing--original draft preparation|writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
3194151	21967920	All authors	2	have contributed substantially to the development of the ideas discussed in this paper, have contributed to drafting and writing the manuscript, and have approved the final version	have contributed substantially to the development of the ideas discussed in this paper, have contributed to drafting and writing the manuscript, and have approved the final version	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5001235	27556157	JP	2	collected the data|participated the design of the method	collected the data	Performed the experiments	Investigation	YES
5001235	27556157	JP	2	collected the data|participated the design of the method	participated the design of the method	Conceived and designed the experiments|Performed the experiments	Methodology	YES
5001235	27556157	JZ	2	collected the data|performed the computational coding and conducted data analysis|drafted the manuscript	collected the data	Performed the experiments	Investigation	YES
5001235	27556157	JZ	2	collected the data|performed the computational coding and conducted data analysis|drafted the manuscript	performed the computational coding and conducted data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5001235	27556157	JZ	2	collected the data|performed the computational coding and conducted data analysis|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5001235	27556157	KH	2	conceived of the study|drafted the manuscript	conceived of the study	Conceived and designed the experiments	Conceptualization	YES
5001235	27556157	KH	2	conceived of the study|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5001235	27556157	ZA	2	collected the data	collected the data	Performed the experiments	Investigation	YES
4398371	25875594	ANH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398371	25875594	ANH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398371	25875594	ANH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398371	25875594	ANH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398371	25875594	BB	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398371	25875594	BB	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4398371	25875594	BW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398371	25875594	BW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398371	25875594	BW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398371	25875594	MB	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
3194152	21967983	All	2	co-authors were involved with the final version and have approved it	co-authors were involved with the final version and have approved it	-	-	NO
3194152	21967983	JCS	2	co-authors were involved with the final version and have approved it	co-authors were involved with the final version and have approved it	-	-	NO
3194152	21967983	VA	2	co-authors were involved with the final version and have approved it	co-authors were involved with the final version and have approved it	-	-	NO
3194152	21967983	WvD	2	co-authors were involved with the final version and have approved it	co-authors were involved with the final version and have approved it	-	-	NO
5432644	28559907	FB	2	conceived the project	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5432644	28559907	J-ZW	2	contributed the mutant screening and mapping	contributed the mutant screening and mapping	Performed the experiments	Investigation	YES
5432644	28559907	JD	2	helped with the performed all experiments with the	helped with the performed all experiments with the	Performed the experiments	Investigation	YES
5432644	28559907	LW	2	designed the experiments|helped with the performed all experiments with the	designed the experiments	Conceived and designed the experiments	Methodology	YES
5432644	28559907	LW	2	designed the experiments|helped with the performed all experiments with the	helped with the performed all experiments with the	Performed the experiments	Investigation	YES
5432644	28559907	PL	2	helped with the performed all experiments with the	helped with the performed all experiments with the	Performed the experiments	Investigation	YES
5432644	28559907	QL	2	designed the experiments|performed all experiments with the|analyzed the data and wrote the article	designed the experiments	Conceived and designed the experiments	Methodology	YES
5432644	28559907	QL	2	designed the experiments|performed all experiments with the|analyzed the data and wrote the article	performed all experiments with the	Performed the experiments	Investigation	YES
5432644	28559907	QL	2	designed the experiments|performed all experiments with the|analyzed the data and wrote the article	analyzed the data and wrote the article	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5432644	28559907	Y-KH	2	conceived the project	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5432644	28559907	Y-LC	2	helped with the performed all experiments with the	helped with the performed all experiments with the	Performed the experiments	Investigation	YES
6359037	30626065	A.R.O.	CRediT	Writing--original draft preparation|Visualization|Funding acquisition	Writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6359037	30626065	A.R.O.	CRediT	Writing--original draft preparation|Visualization|Funding acquisition	Visualization	Analyzed the data	Visualization	YES
6359037	30626065	A.R.O.	CRediT	Writing--original draft preparation|Visualization|Funding acquisition	Funding acquisition	-	Funding acquisition	YES
6359037	30626065	H.-Y.P.C.	CRediT	Investigation|Resources	Investigation	Performed the experiments	Investigation	YES
6359037	30626065	H.-Y.P.C.	CRediT	Investigation|Resources	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6359037	30626065	H.J.L.	CRediT	Conceptualization|Methodology|Formal analysis|Investigation|Data curation|Writing--original draft preparation|Writing--review & editing|Supervision|Project administration|Funding acquisition	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6359037	30626065	H.J.L.	CRediT	Conceptualization|Methodology|Formal analysis|Investigation|Data curation|Writing--original draft preparation|Writing--review & editing|Supervision|Project administration|Funding acquisition	Methodology	Performed the experiments	Methodology	YES
6359037	30626065	H.J.L.	CRediT	Conceptualization|Methodology|Formal analysis|Investigation|Data curation|Writing--original draft preparation|Writing--review & editing|Supervision|Project administration|Funding acquisition	Formal analysis	Analyzed the data	Formal analysis	YES
6359037	30626065	H.J.L.	CRediT	Conceptualization|Methodology|Formal analysis|Investigation|Data curation|Writing--original draft preparation|Writing--review & editing|Supervision|Project administration|Funding acquisition	Investigation	Performed the experiments	Investigation	YES
6359037	30626065	H.J.L.	CRediT	Conceptualization|Methodology|Formal analysis|Investigation|Data curation|Writing--original draft preparation|Writing--review & editing|Supervision|Project administration|Funding acquisition	Data curation	Analyzed the data	Data curation	YES
6359037	30626065	H.J.L.	CRediT	Conceptualization|Methodology|Formal analysis|Investigation|Data curation|Writing--original draft preparation|Writing--review & editing|Supervision|Project administration|Funding acquisition	Writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6359037	30626065	H.J.L.	CRediT	Conceptualization|Methodology|Formal analysis|Investigation|Data curation|Writing--original draft preparation|Writing--review & editing|Supervision|Project administration|Funding acquisition	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6359037	30626065	H.J.L.	CRediT	Conceptualization|Methodology|Formal analysis|Investigation|Data curation|Writing--original draft preparation|Writing--review & editing|Supervision|Project administration|Funding acquisition	Supervision	-	Supervision	YES
6359037	30626065	H.J.L.	CRediT	Conceptualization|Methodology|Formal analysis|Investigation|Data curation|Writing--original draft preparation|Writing--review & editing|Supervision|Project administration|Funding acquisition	Project administration	-	Project administration	YES
6359037	30626065	H.J.L.	CRediT	Conceptualization|Methodology|Formal analysis|Investigation|Data curation|Writing--original draft preparation|Writing--review & editing|Supervision|Project administration|Funding acquisition	Funding acquisition	-	Funding acquisition	YES
6359037	30626065	J.H.Y.	CRediT	Resources	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6359037	30626065	J.L.	CRediT	Conceptualization|Methodology|Formal analysis|Investigation|Data curation|Writing--original draft preparation|Writing--review & editing|Funding acquisition	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6359037	30626065	J.L.	CRediT	Conceptualization|Methodology|Formal analysis|Investigation|Data curation|Writing--original draft preparation|Writing--review & editing|Funding acquisition	Methodology	Performed the experiments	Methodology	YES
6359037	30626065	J.L.	CRediT	Conceptualization|Methodology|Formal analysis|Investigation|Data curation|Writing--original draft preparation|Writing--review & editing|Funding acquisition	Formal analysis	Analyzed the data	Formal analysis	YES
6359037	30626065	J.L.	CRediT	Conceptualization|Methodology|Formal analysis|Investigation|Data curation|Writing--original draft preparation|Writing--review & editing|Funding acquisition	Investigation	Performed the experiments	Investigation	YES
6359037	30626065	J.L.	CRediT	Conceptualization|Methodology|Formal analysis|Investigation|Data curation|Writing--original draft preparation|Writing--review & editing|Funding acquisition	Data curation	Analyzed the data	Data curation	YES
6359037	30626065	J.L.	CRediT	Conceptualization|Methodology|Formal analysis|Investigation|Data curation|Writing--original draft preparation|Writing--review & editing|Funding acquisition	Writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6359037	30626065	J.L.	CRediT	Conceptualization|Methodology|Formal analysis|Investigation|Data curation|Writing--original draft preparation|Writing--review & editing|Funding acquisition	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6359037	30626065	J.L.	CRediT	Conceptualization|Methodology|Formal analysis|Investigation|Data curation|Writing--original draft preparation|Writing--review & editing|Funding acquisition	Funding acquisition	-	Funding acquisition	YES
6359037	30626065	S.J.R.	CRediT	Writing--original draft preparation|Writing--review & editing	Writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6359037	30626065	S.J.R.	CRediT	Writing--original draft preparation|Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6359037	30626065	S.W.C.	CRediT	Conceptualization|Methodology|Formal analysis|Investigation|Writing--original draft preparation	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6359037	30626065	S.W.C.	CRediT	Conceptualization|Methodology|Formal analysis|Investigation|Writing--original draft preparation	Methodology	Performed the experiments	Methodology	YES
6359037	30626065	S.W.C.	CRediT	Conceptualization|Methodology|Formal analysis|Investigation|Writing--original draft preparation	Formal analysis	Analyzed the data	Formal analysis	YES
6359037	30626065	S.W.C.	CRediT	Conceptualization|Methodology|Formal analysis|Investigation|Writing--original draft preparation	Investigation	Performed the experiments	Investigation	YES
6359037	30626065	S.W.C.	CRediT	Conceptualization|Methodology|Formal analysis|Investigation|Writing--original draft preparation	Writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
4396142	25918705	Chao Xu	2	contributed equally to this work as co-first authors	contributed equally to this work as co-first authors	-	-	NO
4396142	25918705	Xin-Xin Wen	2	contributed equally to this work as co-first authors	contributed equally to this work as co-first authors	-	-	NO
5001236	27556417	BH	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5001236	27556417	DC	2	performed the computational coding and implementation	performed the computational coding and implementation	Performed the experiments	Formal analysis|Investigation	YES
5001236	27556417	DX	2	performed the computational coding and implementation	performed the computational coding and implementation	Performed the experiments	Formal analysis|Investigation	YES
5001236	27556417	FS	2	performed the computational coding and implementation	performed the computational coding and implementation	Performed the experiments	Formal analysis|Investigation	YES
5001236	27556417	SZ	2	performed the computational coding and implementation	performed the computational coding and implementation	Performed the experiments	Formal analysis|Investigation	YES
5001236	27556417	WF	2	designed the model|drafted the manuscript	designed the model	Conceived and designed the experiments|Performed the experiments	Methodology	YES
5001236	27556417	WF	2	designed the model|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5001236	27556417	YH	2	conducted data analysis	conducted data analysis	Analyzed the data	Formal analysis	YES
5001236	27556417	YL	2	designed the study|drafted the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5001236	27556417	YL	2	designed the study|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5001236	27556417	YW	2	designed the model	designed the model	Conceived and designed the experiments|Performed the experiments	Methodology	YES
5001236	27556417	ZL	2	performed the computational coding and implementation	performed the computational coding and implementation	Performed the experiments	Formal analysis|Investigation	YES
5433092	28559903	AL	PLoS52	designed research|performed research|analyzed data and discussed results|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
5433092	28559903	AL	PLoS52	designed research|performed research|analyzed data and discussed results|wrote the paper	performed research	Performed the experiments	Investigation	YES
5433092	28559903	AL	PLoS52	designed research|performed research|analyzed data and discussed results|wrote the paper	analyzed data and discussed results	Analyzed the data	Formal analysis	YES
5433092	28559903	AL	PLoS52	designed research|performed research|analyzed data and discussed results|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5433092	28559903	All authors	PLoS52	contributed to improving the paper and approved the final manuscript	contributed to improving the paper and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5433092	28559903	JX	PLoS52	analyzed data and discussed results	analyzed data and discussed results	Analyzed the data	Formal analysis	YES
5433092	28559903	NF	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
5433092	28559903	PZ	PLoS52	designed research|revised the paper	designed research	Conceived and designed the experiments	Methodology	YES
5433092	28559903	PZ	PLoS52	designed research|revised the paper	revised the paper	Wrote the paper	Writing - Review & Editing	YES
5433092	28559903	SY	PLoS52	analyzed data and discussed results	analyzed data and discussed results	Analyzed the data	Formal analysis	YES
5433092	28559903	YA	PLoS52	designed research|revised the paper	designed research	Conceived and designed the experiments	Methodology	YES
5433092	28559903	YA	PLoS52	designed research|revised the paper	revised the paper	Wrote the paper	Writing - Review & Editing	YES
4398372	25874772	CCZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398372	25874772	HC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398372	25874772	HC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398372	25874772	HC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398372	25874772	HF	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398372	25874772	HF	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398372	25874772	KZ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398372	25874772	LW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398372	25874772	PHG	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4398372	25874772	RPZ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398372	25874772	SDZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398372	25874772	ZJZ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5780725	22443176	FH	2	took care of this patient	took care of this patient	Performed the experiments	Investigation	YES
5780725	22443176	HLC	2	significantly helped to revise this letter	significantly helped to revise this letter	Wrote the paper	Writing - Review & Editing	YES
5780725	22443176	JF	2	took care of this patient	took care of this patient	Performed the experiments	Investigation	YES
5780725	22443176	MT	2	took care of this patient|took care of this patient	took care of this patient	Performed the experiments	Investigation	YES
5780725	22443176	MT	2	took care of this patient|took care of this patient	took care of this patient	Performed the experiments	Investigation	YES
5780725	22443176	SH	2	took care of this patient	took care of this patient	Performed the experiments	Investigation	YES
6359056	30597930	A.O.	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
6359056	30597930	E.G.	CRediT	Conceptualization|Project administration|Writing--review & editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6359056	30597930	E.G.	CRediT	Conceptualization|Project administration|Writing--review & editing	Project administration	-	Project administration	YES
6359056	30597930	E.G.	CRediT	Conceptualization|Project administration|Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6359056	30597930	E.P.P.	CRediT	Conceptualization|Investigation|Writing--original draft preparation	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6359056	30597930	E.P.P.	CRediT	Conceptualization|Investigation|Writing--original draft preparation	Investigation	Performed the experiments	Investigation	YES
6359056	30597930	E.P.P.	CRediT	Conceptualization|Investigation|Writing--original draft preparation	Writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6359056	30597930	G.G.	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
6359056	30597930	G.R.	CRediT	Investigation|Writing--original draft preparation	Investigation	Performed the experiments	Investigation	YES
6359056	30597930	G.R.	CRediT	Investigation|Writing--original draft preparation	Writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6359056	30597930	N.S.	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
6359056	30597930	P.G.	CRediT	Resources	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6359056	30597930	R.M.	CRediT	Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6359056	30597930	S.F.	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
3194162	21968079	KM	2	contributed to the conception, design, interpretation and drafting of this manuscript and is sole author	contributed to the conception, design, interpretation and drafting of this manuscript and is sole author	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
4396818	25918720	Hong Bu	2	provided financial support for this work and final approval of the paper	provided financial support for this work and final approval of the paper	-	Funding acquisition	YES
4396818	25918720	Ji Bao	2	contributed equally to this work|designed the study, edited the paper, and provided financial support	contributed equally to this work	-	-	NO
4396818	25918720	Ji Bao	2	contributed equally to this work|designed the study, edited the paper, and provided financial support	designed the study, edited the paper, and provided financial support	Conceived and designed the experiments|Wrote the paper	Funding acquisition|Methodology|Writing - Review & Editing	YES
4396818	25918720	Li Li	2	were responsible for data collection and analysis	were responsible for data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4396818	25918720	Qiong Wu	2	contributed equally to this work|performed the majority of experiments and wrote the paper	contributed equally to this work	-	-	NO
4396818	25918720	Qiong Wu	2	contributed equally to this work|performed the majority of experiments and wrote the paper	performed the majority of experiments and wrote the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5001237	27557108	NS	2	performed data analysis	performed data analysis	Analyzed the data	Formal analysis	YES
5001237	27557108	SW	2	performed data analysis	performed data analysis	Analyzed the data	Formal analysis	YES
5001237	27557108	YQL	2	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5001237	27557108	YW	2	conceived and designed the study|performed data analysis|drafted the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5001237	27557108	YW	2	conceived and designed the study|performed data analysis|drafted the manuscript	performed data analysis	Analyzed the data	Formal analysis	YES
5001237	27557108	YW	2	conceived and designed the study|performed data analysis|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5001237	27557108	ZZ	2	conceived and designed the study|performed data analysis|drafted the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5001237	27557108	ZZ	2	conceived and designed the study|performed data analysis|drafted the manuscript	performed data analysis	Analyzed the data	Formal analysis	YES
5001237	27557108	ZZ	2	conceived and designed the study|performed data analysis|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5433297	28559900	JW	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5433297	28559900	JZ	2	planned and designed the research|wrote the manuscript	planned and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5433297	28559900	JZ	2	planned and designed the research|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5433297	28559900	MA	2	performed experiments|conducted metabolite analyses|wrote the manuscript	performed experiments	Performed the experiments	Investigation	YES
5433297	28559900	MA	2	performed experiments|conducted metabolite analyses|wrote the manuscript	conducted metabolite analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5433297	28559900	MA	2	performed experiments|conducted metabolite analyses|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5433297	28559900	NR	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5433297	28559900	PL	2	performed experiments|conducted metabolite analyses	performed experiments	Performed the experiments	Investigation	YES
5433297	28559900	PL	2	performed experiments|conducted metabolite analyses	conducted metabolite analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6359069	30634643	A.S.	2	designed the work|performed the biological experiments	designed the work	Conceived and designed the experiments	-	YES
6359069	30634643	A.S.	2	designed the work|performed the biological experiments	performed the biological experiments	Performed the experiments	Investigation	YES
6359069	30634643	E.F.	2	synthesized dendrimers	synthesized dendrimers	Performed the experiments	Investigation	YES
6359069	30634643	E.K.A.	2	designed the work|performed the biophysical experiments	designed the work	Conceived and designed the experiments	-	YES
6359069	30634643	E.K.A.	2	designed the work|performed the biophysical experiments	performed the biophysical experiments	Performed the experiments	Investigation	YES
6359069	30634643	M.I.	2	designed the work	designed the work	Conceived and designed the experiments	-	YES
6359069	30634643	O.A.K.	2	designed the work|synthesized dendrimers|performed the biophysical experiments	designed the work	Conceived and designed the experiments	-	YES
6359069	30634643	O.A.K.	2	designed the work|synthesized dendrimers|performed the biophysical experiments	synthesized dendrimers	Performed the experiments	Investigation	YES
6359069	30634643	O.A.K.	2	designed the work|synthesized dendrimers|performed the biophysical experiments	performed the biophysical experiments	Performed the experiments	Investigation	YES
6359069	30634643	all other authors	2	revised it critically	revised it critically	Wrote the paper	Writing - Review & Editing	YES
4398373	25875306	GYW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398373	25875306	GYW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398373	25875306	GYW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398373	25875306	GYW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398373	25875306	GYW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398373	25875306	JRX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398373	25875306	JRX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398373	25875306	JRX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398373	25875306	JRX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398373	25875306	JRX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398373	25875306	JZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398373	25875306	STS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398373	25875306	WQZ	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
3194163	21968091	CM	2	participated in the design of the study, was responsible for its day-to-day coordination, and drafted the manuscript	participated in the design of the study, was responsible for its day-to-day coordination, and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft	YES
3194163	21968091	RP	2	conceived of the study, participated in its coordination, and provided critical input into the manuscript	conceived of the study, participated in its coordination, and provided critical input into the manuscript	Conceived and designed the experiments	Conceptualization|Project administration	YES
4398374	25875653	KTH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398374	25875653	KTH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398374	25875653	KTH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398374	25875653	MPR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398374	25875653	MPR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398374	25875653	MPR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398374	25875653	MPR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5433298	28559902	All	2	authors contributed to the writing of the manuscript, approved the final version, and agree to be accountable to all aspects of the work	authors contributed to the writing of the manuscript, approved the final version, and agree to be accountable to all aspects of the work	Wrote the paper	Writing - Original Draft	YES
5433298	28559902	DN	2	carried out the laboratory work and methodological development on live and dead seeds, and drafted the initial version of the manuscript	carried out the laboratory work and methodological development on live and dead seeds, and drafted the initial version of the manuscript	Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5433298	28559902	LL	2	performed the final assessment of the method we present and led the final drafting of the manuscript	performed the final assessment of the method we present and led the final drafting of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5433298	28559902	PPMI	2	was pivotal in developing and conceptualisation the data for peer-review	was pivotal in developing and conceptualisation the data for peer-review	Conceived and designed the experiments	Conceptualization	YES
5433298	28559902	SOP	2	authors contributed to the writing of the manuscript, approved the final version, and agree to be accountable to all aspects of the work	authors contributed to the writing of the manuscript, approved the final version, and agree to be accountable to all aspects of the work	Wrote the paper	Writing - Original Draft	YES
5433298	28559902	VM	2	is a research assistant who had a working knowledge of barley seed testing and supported dn in the execution of the laboratory based tasks	is a research assistant who had a working knowledge of barley seed testing and supported dn in the execution of the laboratory based tasks	Performed the experiments	Investigation	YES
5780730	22329841	A.S.	2	carried out the laboratory assays	carried out the laboratory assays	Performed the experiments	Investigation	YES
5780730	22329841	C.D.	2	carried out the laboratory assays	carried out the laboratory assays	Performed the experiments	Investigation	YES
5780730	22329841	C.P.	2	statistically analyzed the data	statistically analyzed the data	Analyzed the data	Formal analysis	YES
5780730	22329841	C.T.	2	collected the swabs and entered the data in the database	collected the swabs and entered the data in the database	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5780730	22329841	E.F.	2	examined the patients	examined the patients	Performed the experiments	Investigation	YES
5780730	22329841	G.P.	2	collected the swabs and entered the data in the database	collected the swabs and entered the data in the database	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5780730	22329841	N.P.	2	designed the study and co-wrote the manuscript	designed the study and co-wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5780730	22329841	S.E.	2	designed the study and co-wrote the manuscript	designed the study and co-wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3194164	21968231	All authors	2	contributed to the conception, design, writing and revision of this manuscript, and have given final approval of the version to be published	contributed to the conception, design, writing and revision of this manuscript, and have given final approval of the version to be published	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
6359070	30621174	C.-I.L.	2	led the project and wrote the manuscript	led the project and wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6359070	30621174	C.-P.J.	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
6359070	30621174	K.-H.Y.	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
6359070	30621174	W.-C.C.	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5001238	27557118	All authors	2	have participated study discussion and manuscript preparation	have participated study discussion and manuscript preparation	Wrote the paper	Writing - Original Draft	YES
5001238	27557118	RX	2	conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5001238	27557118	YC	2	designed the methods, performed the experiments and wrote the manuscript	designed the methods, performed the experiments and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
6359103	30669539	B.F.	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
6359103	30669539	H.F.	CRediT	Funding acquisition|Supervision	Funding acquisition	-	Funding acquisition	YES
6359103	30669539	H.F.	CRediT	Funding acquisition|Supervision	Supervision	-	Supervision	YES
6359103	30669539	L.E.	CRediT	Conceptualization|Investigation|Writing--original draft|Writing--review and editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6359103	30669539	L.E.	CRediT	Conceptualization|Investigation|Writing--original draft|Writing--review and editing	Investigation	Performed the experiments	Investigation	YES
6359103	30669539	L.E.	CRediT	Conceptualization|Investigation|Writing--original draft|Writing--review and editing	Writing--original draft	Wrote the paper	Writing - Original Draft	YES
6359103	30669539	L.E.	CRediT	Conceptualization|Investigation|Writing--original draft|Writing--review and editing	Writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6359103	30669539	M.L.B.	CRediT	Funding acquisition|Supervision|Writing--review and editing	Funding acquisition	-	Funding acquisition	YES
6359103	30669539	M.L.B.	CRediT	Funding acquisition|Supervision|Writing--review and editing	Supervision	-	Supervision	YES
6359103	30669539	M.L.B.	CRediT	Funding acquisition|Supervision|Writing--review and editing	Writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6359103	30669539	S.B.	CRediT	Formal analysis|Methodology|Supervision	Formal analysis	Analyzed the data	Formal analysis	YES
6359103	30669539	S.B.	CRediT	Formal analysis|Methodology|Supervision	Methodology	Performed the experiments	Methodology	YES
6359103	30669539	S.B.	CRediT	Formal analysis|Methodology|Supervision	Supervision	-	Supervision	YES
6359103	30669539	Z.S.-L.	CRediT	Conceptualization|Investigation|Writing--original draft|Writing--review and editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6359103	30669539	Z.S.-L.	CRediT	Conceptualization|Investigation|Writing--original draft|Writing--review and editing	Investigation	Performed the experiments	Investigation	YES
6359103	30669539	Z.S.-L.	CRediT	Conceptualization|Investigation|Writing--original draft|Writing--review and editing	Writing--original draft	Wrote the paper	Writing - Original Draft	YES
6359103	30669539	Z.S.-L.	CRediT	Conceptualization|Investigation|Writing--original draft|Writing--review and editing	Writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
4398375	25875018	ARL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398375	25875018	ARL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398375	25875018	ARL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398375	25875018	ARL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398375	25875018	FJF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398375	25875018	FJF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398375	25875018	FJF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398375	25875018	FJF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398375	25875018	JSLP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398375	25875018	JSLP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398375	25875018	JSLP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398375	25875018	JSLP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398375	25875018	MAJ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398375	25875018	MWHP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398375	25875018	MWHP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4398375	25875018	MWHP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4398375	25875018	MWHP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398375	25875018	PDEMV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398375	25875018	PDEMV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398375	25875018	PDEMV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398375	25875018	PDEMV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5001239	27556922	MJB	2	collected the data|drafted the manuscript	collected the data	Performed the experiments	Investigation	YES
5001239	27556922	MJB	2	collected the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5001239	27556922	XG	2	designed the project|performed the experiments and analyzed the data|drafted the manuscript	designed the project	Conceived and designed the experiments	Methodology	YES
5001239	27556922	XG	2	designed the project|performed the experiments and analyzed the data|drafted the manuscript	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5001239	27556922	XG	2	designed the project|performed the experiments and analyzed the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5001239	27556922	YW	2	designed the project|collected the data|performed the experiments and analyzed the data|drafted the manuscript	designed the project	Conceived and designed the experiments	Methodology	YES
5001239	27556922	YW	2	designed the project|collected the data|performed the experiments and analyzed the data|drafted the manuscript	collected the data	Performed the experiments	Investigation	YES
5001239	27556922	YW	2	designed the project|collected the data|performed the experiments and analyzed the data|drafted the manuscript	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5001239	27556922	YW	2	designed the project|collected the data|performed the experiments and analyzed the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5001239	27556922	ZZ	2	designed the project|drafted the manuscript	designed the project	Conceived and designed the experiments	Methodology	YES
5001239	27556922	ZZ	2	designed the project|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4397470	25922836	Afsaneh Shirani	2	designed the study|managed the data linkage, ensured the data integrity, carried out the statistical analyses, and wrote the first draft of the paper	designed the study	Conceived and designed the experiments	Methodology	YES
4397470	25922836	Afsaneh Shirani	2	designed the study|managed the data linkage, ensured the data integrity, carried out the statistical analyses, and wrote the first draft of the paper	managed the data linkage, ensured the data integrity, carried out the statistical analyses, and wrote the first draft of the paper	Analyzed the data|Wrote the paper	Data curation|Formal analysis|Writing - Original Draft	YES
4397470	25922836	Helen Tremlett	2	designed the study|supervised the study, revised the paper, and obtained funding for the study	designed the study	Conceived and designed the experiments	Methodology	YES
4397470	25922836	Helen Tremlett	2	designed the study|supervised the study, revised the paper, and obtained funding for the study	supervised the study, revised the paper, and obtained funding for the study	Wrote the paper	Funding acquisition|Supervision|Writing - Review & Editing	YES
4397470	25922836	Joel Oger	2	read the paper, provided comments, and approved the final version of the paper	read the paper, provided comments, and approved the final version of the paper	-	-	NO
4397470	25922836	John Petkau	2	provided statistical advice	provided statistical advice	Analyzed the data	Formal analysis	YES
4397470	25922836	Mohammad Ehsanul Karim	2	provided statistical advice	provided statistical advice	Analyzed the data	Formal analysis	YES
4397470	25922836	Paul Gustafson	2	provided statistical advice	provided statistical advice	Analyzed the data	Formal analysis	YES
4397470	25922836	Yinshan Zhao	2	designed the study|provided statistical advice	designed the study	Conceived and designed the experiments	Methodology	YES
4397470	25922836	Yinshan Zhao	2	designed the study|provided statistical advice	provided statistical advice	Analyzed the data	Formal analysis	YES
3194165	21968262	RSR	2	as the sole author|approved the final version of this manuscript	as the sole author	-	-	NO
3194165	21968262	RSR	2	as the sole author|approved the final version of this manuscript	approved the final version of this manuscript	-	-	NO
5434104	28567048	AM	7	Designed the work, revised it critically for intellectual content and approval of final version to be published	Designed the work, revised it critically for intellectual content and approval of final version to be published	Conceived and designed the experiments|Wrote the paper	Writing - Review & Editing	YES
5434104	28567048	FB	7	Acquisition of data, analysis and interpretation of both phenotypic and molecular aspects of the work, and drafted the work	Acquisition of data, analysis and interpretation of both phenotypic and molecular aspects of the work, and drafted the work	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5434104	28567048	GO	7	Supervision of the field and quantitative genetics aspect of the work, contributed to revising it critically for intellectual content and approval of final version to be published	Supervision of the field and quantitative genetics aspect of the work, contributed to revising it critically for intellectual content and approval of final version to be published	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Review & Editing	YES
5434104	28567048	JC	7	Analysis of the molecular data during the development of the population, designed the form of selection to be used, revised and approved the final version to be published	Analysis of the molecular data during the development of the population, designed the form of selection to be used, revised and approved the final version to be published	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
5434104	28567048	MG	7	Designed and supervised the molecular aspect of the work, revised the aspect of the work critically for intellectual content and also approved the final version to be published	Designed and supervised the molecular aspect of the work, revised the aspect of the work critically for intellectual content and also approved the final version to be published	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Review & Editing	YES
5434104	28567048	NU	7	Acquisition, analysis, and interpretation of molecular data	Acquisition, analysis, and interpretation of molecular data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5434104	28567048	SH	7	Substantial contribution to the design, analysis and interpretation of molecular data while developing the population	Substantial contribution to the design, analysis and interpretation of molecular data while developing the population	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5001240	27556418	LZ	2	developed cbdn and procedure of experiment|implemented the cbdn method in matlab|did the experiments on simulation and real data|wrote the manuscript	developed cbdn and procedure of experiment	Performed the experiments	Investigation	YES
5001240	27556418	LZ	2	developed cbdn and procedure of experiment|implemented the cbdn method in matlab|did the experiments on simulation and real data|wrote the manuscript	implemented the cbdn method in matlab	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5001240	27556418	LZ	2	developed cbdn and procedure of experiment|implemented the cbdn method in matlab|did the experiments on simulation and real data|wrote the manuscript	did the experiments on simulation and real data	Performed the experiments	Formal analysis|Investigation	YES
5001240	27556418	LZ	2	developed cbdn and procedure of experiment|implemented the cbdn method in matlab|did the experiments on simulation and real data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5001240	27556418	SL	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5001240	27556418	XK	2	did the experiments on simulation and real data	did the experiments on simulation and real data	Performed the experiments	Formal analysis|Investigation	YES
5001240	27556418	YK	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4398376	25874547	BM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4398376	25874547	BM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398376	25874547	CJU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398376	25874547	CJU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398376	25874547	CJU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398376	25874547	CJU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398376	25874547	CJU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398376	25874547	GJF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398376	25874547	GJF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398376	25874547	GJF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398376	25874547	GJF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398376	25874547	GJF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398376	25874547	LJR	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398376	25874547	LJR	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398376	25874547	LJR	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398376	25874547	LJR	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398376	25874547	MMS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398376	25874547	MMS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398376	25874547	MMS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398376	25874547	MMS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398376	25874547	MMS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398376	25874547	MW	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398376	25874547	MW	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398376	25874547	MW	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398376	25874547	MW	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398376	25874547	ZJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398376	25874547	ZJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398376	25874547	ZJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398376	25874547	ZJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398376	25874547	ZJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3194166	21968292	DK	2	was responsible for the study design|contributed to final writing and editing	was responsible for the study design	Conceived and designed the experiments	Methodology	YES
3194166	21968292	DK	2	was responsible for the study design|contributed to final writing and editing	contributed to final writing and editing	Wrote the paper	Writing - Review & Editing	YES
3194166	21968292	KF	2	carried out the data collection, performed the analysis, and led the writing of the manuscript	carried out the data collection, performed the analysis, and led the writing of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4397480	25922835	Jane Kim	PLoS52	performed laboratory assays	performed laboratory assays	Performed the experiments	Investigation	YES
4397480	25922835	Linda Xiao	PLoS52	performed laboratory assays	performed laboratory assays	Performed the experiments	Investigation	YES
4397480	25922835	Weiguo Lao	PLoS52	performed laboratory assays	performed laboratory assays	Performed the experiments	Investigation	YES
4397480	25922835	Xianqin Qu	PLoS52	designed research|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
4397480	25922835	Xianqin Qu	PLoS52	designed research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397480	25922835	Xing Liang Jin	PLoS52	designed research|performed laboratory assays	designed research	Conceived and designed the experiments	Methodology	YES
4397480	25922835	Xing Liang Jin	PLoS52	designed research|performed laboratory assays	performed laboratory assays	Performed the experiments	Investigation	YES
5434136	28567052	AM	2	conceived the article|wrote the first draft of the manuscript	conceived the article	Conceived and designed the experiments	Conceptualization	YES
5434136	28567052	AM	2	conceived the article|wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
5434136	28567052	BG	2	wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
5434136	28567052	DC	2	conceived the article|wrote the first draft of the manuscript|revised and finalized	conceived the article	Conceived and designed the experiments	Conceptualization	YES
5434136	28567052	DC	2	conceived the article|wrote the first draft of the manuscript|revised and finalized	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
5434136	28567052	DC	2	conceived the article|wrote the first draft of the manuscript|revised and finalized	revised and finalized	Wrote the paper	Writing - Review & Editing	YES
5434136	28567052	JL	2	wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
6359116	30621136	A.F.	CRediT	Conceptualization|methodology|software|formal analysis|investigation|data curation|writing--original draft preparation|writing--review and editing|visualization|supervision	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6359116	30621136	A.F.	CRediT	Conceptualization|methodology|software|formal analysis|investigation|data curation|writing--original draft preparation|writing--review and editing|visualization|supervision	methodology	Performed the experiments	Methodology	YES
6359116	30621136	A.F.	CRediT	Conceptualization|methodology|software|formal analysis|investigation|data curation|writing--original draft preparation|writing--review and editing|visualization|supervision	software	Contributed reagents/materials/analysis tools	Software	YES
6359116	30621136	A.F.	CRediT	Conceptualization|methodology|software|formal analysis|investigation|data curation|writing--original draft preparation|writing--review and editing|visualization|supervision	formal analysis	Analyzed the data	Formal analysis	YES
6359116	30621136	A.F.	CRediT	Conceptualization|methodology|software|formal analysis|investigation|data curation|writing--original draft preparation|writing--review and editing|visualization|supervision	investigation	Performed the experiments	Investigation	YES
6359116	30621136	A.F.	CRediT	Conceptualization|methodology|software|formal analysis|investigation|data curation|writing--original draft preparation|writing--review and editing|visualization|supervision	data curation	Analyzed the data	Data curation	YES
6359116	30621136	A.F.	CRediT	Conceptualization|methodology|software|formal analysis|investigation|data curation|writing--original draft preparation|writing--review and editing|visualization|supervision	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6359116	30621136	A.F.	CRediT	Conceptualization|methodology|software|formal analysis|investigation|data curation|writing--original draft preparation|writing--review and editing|visualization|supervision	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6359116	30621136	A.F.	CRediT	Conceptualization|methodology|software|formal analysis|investigation|data curation|writing--original draft preparation|writing--review and editing|visualization|supervision	visualization	Analyzed the data	Visualization	YES
6359116	30621136	A.F.	CRediT	Conceptualization|methodology|software|formal analysis|investigation|data curation|writing--original draft preparation|writing--review and editing|visualization|supervision	supervision	-	Supervision	YES
6359116	30621136	A.F.-C.	CRediT	methodology|validation|writing--review and editing	methodology	Performed the experiments	Methodology	YES
6359116	30621136	A.F.-C.	CRediT	methodology|validation|writing--review and editing	validation	Performed the experiments	Validation	YES
6359116	30621136	A.F.-C.	CRediT	methodology|validation|writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6359116	30621136	A.M.	CRediT	methodology|investigation	methodology	Performed the experiments	Methodology	YES
6359116	30621136	A.M.	CRediT	methodology|investigation	investigation	Performed the experiments	Investigation	YES
6359116	30621136	C.R.M.	CRediT	resources|writing--review and editing|project administration|funding acquisition	resources	Contributed reagents/materials/analysis tools	Resources	YES
6359116	30621136	C.R.M.	CRediT	resources|writing--review and editing|project administration|funding acquisition	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6359116	30621136	C.R.M.	CRediT	resources|writing--review and editing|project administration|funding acquisition	project administration	-	Project administration	YES
6359116	30621136	C.R.M.	CRediT	resources|writing--review and editing|project administration|funding acquisition	funding acquisition	-	Funding acquisition	YES
6359116	30621136	L.M.-O.	CRediT	methodology|software|investigation	methodology	Performed the experiments	Methodology	YES
6359116	30621136	L.M.-O.	CRediT	methodology|software|investigation	software	Contributed reagents/materials/analysis tools	Software	YES
6359116	30621136	L.M.-O.	CRediT	methodology|software|investigation	investigation	Performed the experiments	Investigation	YES
6359116	30621136	R.M.	CRediT	Conceptualization|formal analysis|resources|writing--review and editing|supervision|project administration|funding acquisition	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6359116	30621136	R.M.	CRediT	Conceptualization|formal analysis|resources|writing--review and editing|supervision|project administration|funding acquisition	formal analysis	Analyzed the data	Formal analysis	YES
6359116	30621136	R.M.	CRediT	Conceptualization|formal analysis|resources|writing--review and editing|supervision|project administration|funding acquisition	resources	Contributed reagents/materials/analysis tools	Resources	YES
6359116	30621136	R.M.	CRediT	Conceptualization|formal analysis|resources|writing--review and editing|supervision|project administration|funding acquisition	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6359116	30621136	R.M.	CRediT	Conceptualization|formal analysis|resources|writing--review and editing|supervision|project administration|funding acquisition	supervision	-	Supervision	YES
6359116	30621136	R.M.	CRediT	Conceptualization|formal analysis|resources|writing--review and editing|supervision|project administration|funding acquisition	project administration	-	Project administration	YES
6359116	30621136	R.M.	CRediT	Conceptualization|formal analysis|resources|writing--review and editing|supervision|project administration|funding acquisition	funding acquisition	-	Funding acquisition	YES
3197468	21988905	BW	2	participated in study design, coordination, data collection, data analysis and drafting of the manuscript	participated in study design, coordination, data collection, data analysis and drafting of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Project administration|Writing - Original Draft	YES
3197468	21988905	DF	2	contributed to data analysis and drafting of the manuscript	contributed to data analysis and drafting of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3197468	21988905	JD	2	contributed to data analysis and drafting of the manuscript	contributed to data analysis and drafting of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3197468	21988905	RP	2	participated in study design, coordination, data collection, data analysis and drafting of the manuscript	participated in study design, coordination, data collection, data analysis and drafting of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Project administration|Writing - Original Draft	YES
3197468	21988905	SK	2	participated in study design, coordination and drafting of the manuscript	participated in study design, coordination and drafting of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft	YES
3197468	21988905	WJ	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5434141	28567050	AB	2	designed the study|performed the genetic analyses|drafted the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5434141	28567050	AB	2	designed the study|performed the genetic analyses|drafted the manuscript	performed the genetic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5434141	28567050	AB	2	designed the study|performed the genetic analyses|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5434141	28567050	AF	2	designed the study|collected samples	designed the study	Conceived and designed the experiments	Methodology	YES
5434141	28567050	AF	2	designed the study|collected samples	collected samples	Performed the experiments	Investigation	YES
5434141	28567050	All authors	2	contributed to the final version	contributed to the final version	-	-	NO
5434141	28567050	BD	2	collected samples	collected samples	Performed the experiments	Investigation	YES
5434141	28567050	CB-S	2	performed the genetic analyses|drafted the manuscript	performed the genetic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5434141	28567050	CB-S	2	performed the genetic analyses|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5434141	28567050	DD	2	designed the study|drafted the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5434141	28567050	DD	2	designed the study|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5434141	28567050	HT	2	collected samples	collected samples	Performed the experiments	Investigation	YES
5434141	28567050	LZ	2	performed dna extraction	performed dna extraction	Performed the experiments	Investigation	YES
5434141	28567050	MC	2	performed dna extraction	performed dna extraction	Performed the experiments	Investigation	YES
5434141	28567050	MG	2	designed the study|collected samples	designed the study	Conceived and designed the experiments	Methodology	YES
5434141	28567050	MG	2	designed the study|collected samples	collected samples	Performed the experiments	Investigation	YES
5434141	28567050	MP	2	collected samples|performed dna extraction	collected samples	Performed the experiments	Investigation	YES
5434141	28567050	MP	2	collected samples|performed dna extraction	performed dna extraction	Performed the experiments	Investigation	YES
5434141	28567050	NK	2	designed the study|drafted the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5434141	28567050	NK	2	designed the study|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5434141	28567050	OD	2	collected samples|performed dna extraction|performed the genetic analyses|drafted the manuscript	collected samples	Performed the experiments	Investigation	YES
5434141	28567050	OD	2	collected samples|performed dna extraction|performed the genetic analyses|drafted the manuscript	performed dna extraction	Performed the experiments	Investigation	YES
5434141	28567050	OD	2	collected samples|performed dna extraction|performed the genetic analyses|drafted the manuscript	performed the genetic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5434141	28567050	OD	2	collected samples|performed dna extraction|performed the genetic analyses|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5434141	28567050	OS	2	collected samples	collected samples	Performed the experiments	Investigation	YES
5434141	28567050	PCR	2	and sequencing	and sequencing	Performed the experiments	Investigation	YES
5434141	28567050	YV	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5001241	27535360	AJM	2	who is also a main contibutor to this manuscript, envisioned and developed large components of the software	who is also a main contibutor to this manuscript, envisioned and developed large components of the software	Contributed reagents/materials/analysis tools	Software	YES
5001241	27535360	JWP	2	is a main contributor to design of the project and author of this manuscript	is a main contributor to design of the project and author of this manuscript	Conceived and designed the experiments	Methodology	YES
5001241	27535360	TJR	2	is the current lead developer for the project and a contributor to the manuscript	is the current lead developer for the project and a contributor to the manuscript	Wrote the paper	Writing - Original Draft	YES
6359122	30654435	A.R.B.	CRediT	resources|writing--original draft preparation|writing--review and editing	resources	Contributed reagents/materials/analysis tools	Resources	YES
6359122	30654435	A.R.B.	CRediT	resources|writing--original draft preparation|writing--review and editing	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6359122	30654435	A.R.B.	CRediT	resources|writing--original draft preparation|writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6359122	30654435	F.R.	CRediT	resources|writing--review and editing	resources	Contributed reagents/materials/analysis tools	Resources	YES
6359122	30654435	F.R.	CRediT	resources|writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6359122	30654435	F.T.	CRediT	data curation|writing--original draft preparation	data curation	Analyzed the data	Data curation	YES
6359122	30654435	F.T.	CRediT	data curation|writing--original draft preparation	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6359122	30654435	M.C.B.	CRediT	data curation|resources	data curation	Analyzed the data	Data curation	YES
6359122	30654435	M.C.B.	CRediT	data curation|resources	resources	Contributed reagents/materials/analysis tools	Resources	YES
6359122	30654435	V.P.	CRediT	data curation|writing--original draft preparation	data curation	Analyzed the data	Data curation	YES
6359122	30654435	V.P.	CRediT	data curation|writing--original draft preparation	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
3199227	21970719	TWM	2	is responsible for writing and authorizing this manuscript	is responsible for writing and authorizing this manuscript	Wrote the paper	Writing - Original Draft	YES
4398378	25874886	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Searching literature	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398378	25874886	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Searching literature	Performed the experiments	Performed the experiments	Investigation	YES
4398378	25874886	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Searching literature	Analyzed the data	Analyzed the data	Formal analysis	YES
4398378	25874886	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Searching literature	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398378	25874886	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Searching literature	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398378	25874886	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Searching literature	Searching literature	-	Formal analysis	YES
4398378	25874886	HY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Searching literature	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398378	25874886	HY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Searching literature	Performed the experiments	Performed the experiments	Investigation	YES
4398378	25874886	HY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Searching literature	Analyzed the data	Analyzed the data	Formal analysis	YES
4398378	25874886	HY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Searching literature	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398378	25874886	HY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Searching literature	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398378	25874886	HY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Searching literature	Searching literature	-	Formal analysis	YES
4398378	25874886	MA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Searching literature	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398378	25874886	MA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Searching literature	Performed the experiments	Performed the experiments	Investigation	YES
4398378	25874886	MA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Searching literature	Analyzed the data	Analyzed the data	Formal analysis	YES
4398378	25874886	MA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Searching literature	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398378	25874886	MA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Searching literature	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398378	25874886	MA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Searching literature	Searching literature	-	Formal analysis	YES
3204275	21955541	BE	2	contributed to acquisition of data, interpretation of data, and critical revisions of the manuscript	contributed to acquisition of data, interpretation of data, and critical revisions of the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Review & Editing	YES
3204275	21955541	CRC	2	contributed to acquisition of data, interpretation of data, and critical revisions of the manuscript	contributed to acquisition of data, interpretation of data, and critical revisions of the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Review & Editing	YES
3204275	21955541	CTY	2	contributed to conception and design of the study, acquisition of data, interpretation of data, drafting the manuscript, and critical revisions of the manuscript	contributed to conception and design of the study, acquisition of data, interpretation of data, drafting the manuscript, and critical revisions of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
3204275	21955541	DN	2	contributed to conception and design of the study, acquisition of data, interpretation of data, drafting the manuscript, and critical revisions of the manuscript	contributed to conception and design of the study, acquisition of data, interpretation of data, drafting the manuscript, and critical revisions of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
3204275	21955541	DRB	2	contributed to acquisition of data, interpretation of data, and critical revisions of the manuscript	contributed to acquisition of data, interpretation of data, and critical revisions of the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Review & Editing	YES
3204275	21955541	DW	2	contributed to acquisition of data, data analysis, interpretation of data, drafting the manuscript, and critical revisions of the manuscript	contributed to acquisition of data, data analysis, interpretation of data, drafting the manuscript, and critical revisions of the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
3204275	21955541	EHG	2	contributed to conception and design of the study, acquisition of data, data analysis, interpretation of data, drafting the manuscript, and critical revisions of the manuscript	contributed to conception and design of the study, acquisition of data, data analysis, interpretation of data, drafting the manuscript, and critical revisions of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
3204275	21955541	GRS	2	contributed to conception and design of the study, acquisition of data, interpretation of data, drafting the manuscript, and critical revisions of the manuscript	contributed to conception and design of the study, acquisition of data, interpretation of data, drafting the manuscript, and critical revisions of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
3204275	21955541	JAO	2	contributed to acquisition of data, interpretation of data, drafting the manuscript, and critical revisions of the manuscript	contributed to acquisition of data, interpretation of data, drafting the manuscript, and critical revisions of the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
3204275	21955541	JNM	2	contributed to conception and design of the study, acquisition of data, data analysis, interpretation of data, drafting the manuscript, and critical revisions of the manuscript	contributed to conception and design of the study, acquisition of data, data analysis, interpretation of data, drafting the manuscript, and critical revisions of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
3204275	21955541	KWK	2	contributed to conception and design of the study, acquisition of data, data analysis, interpretation of data, drafting the manuscript and critical revisions of the manuscript	contributed to conception and design of the study, acquisition of data, data analysis, interpretation of data, drafting the manuscript and critical revisions of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
3204275	21955541	MBB	2	contributed to acquisition of data, interpretation of data, and critical revisions of the manuscript	contributed to acquisition of data, interpretation of data, and critical revisions of the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Review & Editing	YES
3204275	21955541	PB	2	contributed to acquisition of data, interpretation of data, and critical revisions of the manuscript	contributed to acquisition of data, interpretation of data, and critical revisions of the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Review & Editing	YES
3204275	21955541	PJE	2	contributed to acquisition of data, data analysis, interpretation of data, drafting the manuscript, and critical revisions of the manuscript	contributed to acquisition of data, data analysis, interpretation of data, drafting the manuscript, and critical revisions of the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
3204275	21955541	PO	2	contributed to acquisition of data, interpretation of data, and critical revisions of the manuscript	contributed to acquisition of data, interpretation of data, and critical revisions of the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Review & Editing	YES
3204275	21955541	PWH	2	contributed to conception and design of the study, data analysis, interpretation of data, drafting the manuscript, and critical revisions of the manuscript	contributed to conception and design of the study, data analysis, interpretation of data, drafting the manuscript, and critical revisions of the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
3204275	21955541	SK	2	contributed to acquisition of data, and critical revisions of the manuscript	contributed to acquisition of data, and critical revisions of the manuscript	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Resources|Writing - Review & Editing	YES
5001242	27556597	CY	2	provided biological interpretation of results on real data	provided biological interpretation of results on real data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5001242	27556597	JM	2	help design the validation experiments	help design the validation experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Validation	YES
5001242	27556597	MKR	2	provided biological interpretation of results on real data	provided biological interpretation of results on real data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5001242	27556597	SZ	2	help design the validation experiments	help design the validation experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Validation	YES
5001242	27556597	XC	2	designed the method and drafted the manuscript	designed the method and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5001242	27556597	YH	2	supervised the work, made critical revisions of the paper, and approved the submission of the manuscript	supervised the work, made critical revisions of the paper, and approved the submission of the manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
5434148	28567047	RD	2	revised the article	revised the article	Wrote the paper	Writing - Review & Editing	YES
5434148	28567047	XR	2	collected data from literature and wrote the manuscript	collected data from literature and wrote the manuscript	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6359179	30634665	A.K.R.	CRediT	Conceptualization	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6359179	30634665	A.S.T.	CRediT	Data curation	Data curation	Analyzed the data	Data curation	YES
6359179	30634665	N.A.A.	CRediT	Writing-original draft preparation|Writing-review & editing	Writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
6359179	30634665	N.A.A.	CRediT	Writing-original draft preparation|Writing-review & editing	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6359179	30634665	S.K.B.	CRediT	Conceptualization|Methodology|Supervision|Funding acquisition	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6359179	30634665	S.K.B.	CRediT	Conceptualization|Methodology|Supervision|Funding acquisition	Methodology	Performed the experiments	Methodology	YES
6359179	30634665	S.K.B.	CRediT	Conceptualization|Methodology|Supervision|Funding acquisition	Supervision	-	Supervision	YES
6359179	30634665	S.K.B.	CRediT	Conceptualization|Methodology|Supervision|Funding acquisition	Funding acquisition	-	Funding acquisition	YES
6359179	30634665	S.M.	CRediT	Conceptualization|Methodology|Resources|Writing-original draft preparation|Writing-review & editing|Supervision|Funding acquisition	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6359179	30634665	S.M.	CRediT	Conceptualization|Methodology|Resources|Writing-original draft preparation|Writing-review & editing|Supervision|Funding acquisition	Methodology	Performed the experiments	Methodology	YES
6359179	30634665	S.M.	CRediT	Conceptualization|Methodology|Resources|Writing-original draft preparation|Writing-review & editing|Supervision|Funding acquisition	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6359179	30634665	S.M.	CRediT	Conceptualization|Methodology|Resources|Writing-original draft preparation|Writing-review & editing|Supervision|Funding acquisition	Writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
6359179	30634665	S.M.	CRediT	Conceptualization|Methodology|Resources|Writing-original draft preparation|Writing-review & editing|Supervision|Funding acquisition	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6359179	30634665	S.M.	CRediT	Conceptualization|Methodology|Resources|Writing-original draft preparation|Writing-review & editing|Supervision|Funding acquisition	Supervision	-	Supervision	YES
6359179	30634665	S.M.	CRediT	Conceptualization|Methodology|Resources|Writing-original draft preparation|Writing-review & editing|Supervision|Funding acquisition	Funding acquisition	-	Funding acquisition	YES
6359179	30634665	T.M.	CRediT	Methodology	Methodology	Performed the experiments	Methodology	YES
4398379	25875862	AGP	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398379	25875862	AGP	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398379	25875862	CM	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398379	25875862	EE	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398379	25875862	EE	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398379	25875862	EM	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398379	25875862	EV	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398379	25875862	FA	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398379	25875862	FA	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398379	25875862	FA	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398379	25875862	IGO	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398379	25875862	IGO	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398379	25875862	IGO	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398379	25875862	SA	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398379	25875862	SA	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398379	25875862	SA	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3753761	23997760	Alexander Heidrich	2	conceived the study, carried out ct measurements, participated in rule set development, and drafted the paper	conceived the study, carried out ct measurements, participated in rule set development, and drafted the paper	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
3753761	23997760	Hans Peter Saluz	2	participated in the design of the study and helped drafting the paper	participated in the design of the study and helped drafting the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3753761	23997760	Jana Schmidt	2	performed data analysis and helped drafting the paper	performed data analysis and helped drafting the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3753761	23997760	Johannes Zimmermann	2	participated in rule set development and helped drafting the paper	participated in rule set development and helped drafting the paper	Wrote the paper	Writing - Original Draft	YES
3207867	22014096	ADW	2	were involved in the early iteration of the manuscript and reviewed and made substantive contributions to the drafts	were involved in the early iteration of the manuscript and reviewed and made substantive contributions to the drafts	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3207867	22014096	All authors	2	have contributed substantively in critically revising the content of the manuscript	have contributed substantively in critically revising the content of the manuscript	Wrote the paper	Writing - Review & Editing	YES
3207867	22014096	BJM	2	conceptualized the manuscript|did extensive reviews of subsequent drafts	conceptualized the manuscript	Conceived and designed the experiments	Conceptualization	YES
3207867	22014096	BJM	2	conceptualized the manuscript|did extensive reviews of subsequent drafts	did extensive reviews of subsequent drafts	Wrote the paper	Writing - Original Draft	YES
3207867	22014096	DAC	2	were involved in the early iteration of the manuscript and reviewed and made substantive contributions to the drafts	were involved in the early iteration of the manuscript and reviewed and made substantive contributions to the drafts	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3207867	22014096	DS	2	were involved in the early iteration of the manuscript and reviewed and made substantive contributions to the drafts|provided crucial data on male circumcision implementation	were involved in the early iteration of the manuscript and reviewed and made substantive contributions to the drafts	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3207867	22014096	DS	2	were involved in the early iteration of the manuscript and reviewed and made substantive contributions to the drafts|provided crucial data on male circumcision implementation	provided crucial data on male circumcision implementation	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
3207867	22014096	GB	2	were involved in the early iteration of the manuscript and reviewed and made substantive contributions to the drafts	were involved in the early iteration of the manuscript and reviewed and made substantive contributions to the drafts	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3207867	22014096	JB	2	were involved in the early iteration of the manuscript and reviewed and made substantive contributions to the drafts	were involved in the early iteration of the manuscript and reviewed and made substantive contributions to the drafts	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3207867	22014096	JBE	2	read and provided insightful comments in the final revisions	read and provided insightful comments in the final revisions	Wrote the paper	Writing - Review & Editing	YES
3207867	22014096	JDK	2	were involved in the early iteration of the manuscript and reviewed and made substantive contributions to the drafts	were involved in the early iteration of the manuscript and reviewed and made substantive contributions to the drafts	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3207867	22014096	NS	2	were involved in the early iteration of the manuscript and reviewed and made substantive contributions to the drafts	were involved in the early iteration of the manuscript and reviewed and made substantive contributions to the drafts	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3207867	22014096	RA	2	was involved in editing and formatting the manuscript in various stages	was involved in editing and formatting the manuscript in various stages	Wrote the paper	Writing - Review & Editing	YES
3207867	22014096	RGW	2	conceptualized the manuscript|drafted and developed the manuscript	conceptualized the manuscript	Conceived and designed the experiments	Conceptualization	YES
3207867	22014096	RGW	2	conceptualized the manuscript|drafted and developed the manuscript	drafted and developed the manuscript	Wrote the paper	Writing - Original Draft	YES
3207867	22014096	SAB	2	were involved in the early iteration of the manuscript and reviewed and made substantive contributions to the drafts	were involved in the early iteration of the manuscript and reviewed and made substantive contributions to the drafts	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5434153	28567053	FW	2	performed research and conducted data analyses	performed research and conducted data analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5434153	28567053	XS	2	performed research and conducted data analyses	performed research and conducted data analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5434153	28567053	YH	2	performed research and conducted data analyses	performed research and conducted data analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5434153	28567053	ZX	2	designed the research|performed research and conducted data analyses|wrote and revised the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
5434153	28567053	ZX	2	designed the research|performed research and conducted data analyses|wrote and revised the manuscript	performed research and conducted data analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5434153	28567053	ZX	2	designed the research|performed research and conducted data analyses|wrote and revised the manuscript	wrote and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5780756	22487301	BMS	2	assisted with the animal experiments	assisted with the animal experiments	Performed the experiments	Investigation	YES
5780756	22487301	HMK	2	assisted with the animal experiments	assisted with the animal experiments	Performed the experiments	Investigation	YES
5780756	22487301	HSK	2	assisted with the animal experiments	assisted with the animal experiments	Performed the experiments	Investigation	YES
5780756	22487301	NTN	2	drafted the manuscript and performed experiments on the development of the vaccine strain and its protective efficacy in chickens	drafted the manuscript and performed experiments on the development of the vaccine strain and its protective efficacy in chickens	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5780756	22487301	SHS	2	conceived the study and participated in its design and coordination	conceived the study and participated in its design and coordination	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
5780756	22487301	YMK	2	assisted with the animal experiments	assisted with the animal experiments	Performed the experiments	Investigation	YES
3214767	22017821	AHM	2	prepared the study proposal, collected and analyzed the data, interpreted the findings and wrote the manuscript	prepared the study proposal, collected and analyzed the data, interpreted the findings and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3214767	22017821	KMM	2	was involved in developing the study proposal and reviewing the manuscript	was involved in developing the study proposal and reviewing the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3214767	22017821	MMS	2	was involved in supervising the data collection and reviewing the manuscript	was involved in supervising the data collection and reviewing the manuscript	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Review & Editing	YES
3214767	22017821	OM	2	was involved in developing the study proposal, supervising the data collection and reviewing the manuscript	was involved in developing the study proposal, supervising the data collection and reviewing the manuscript	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
3214767	22017821	SGH	2	was involved in developing the study proposal and reviewing the manuscript	was involved in developing the study proposal and reviewing the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4398380	25875647	CAC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398380	25875647	CAC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398380	25875647	CAC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398380	25875647	CAC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398380	25875647	NP	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398380	25875647	NP	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4398380	25875647	NP	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398380	25875647	WCT	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398380	25875647	WCT	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398380	25875647	WMG	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398380	25875647	WMG	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5001243	27535232	AF	2	performed the sample collection, preparation, and data acquisition	performed the sample collection, preparation, and data acquisition	Performed the experiments	Investigation	YES
5001243	27535232	CDP	2	performed the sample collection, preparation, and data acquisition	performed the sample collection, preparation, and data acquisition	Performed the experiments	Investigation	YES
5001243	27535232	GY	2	supervised the analysis	supervised the analysis	-	Supervision	YES
5001243	27535232	HWR	2	designed the study|supervised the analysis|wrote the manuscript with contributions from all other authors	designed the study	Conceived and designed the experiments	Methodology	YES
5001243	27535232	HWR	2	designed the study|supervised the analysis|wrote the manuscript with contributions from all other authors	supervised the analysis	-	Supervision	YES
5001243	27535232	HWR	2	designed the study|supervised the analysis|wrote the manuscript with contributions from all other authors	wrote the manuscript with contributions from all other authors	Wrote the paper	Writing - Original Draft	YES
5001243	27535232	MW	2	developed the methods and implemented the algorithms|designed the study|wrote the manuscript with contributions from all other authors	developed the methods and implemented the algorithms	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Software	YES
5001243	27535232	MW	2	developed the methods and implemented the algorithms|designed the study|wrote the manuscript with contributions from all other authors	designed the study	Conceived and designed the experiments	Methodology	YES
5001243	27535232	MW	2	developed the methods and implemented the algorithms|designed the study|wrote the manuscript with contributions from all other authors	wrote the manuscript with contributions from all other authors	Wrote the paper	Writing - Original Draft	YES
5001243	27535232	THT	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
4398921	25922843	Anshuman Verma	2	carried out ngs experiment, conducted data analysis, and revised the paper	carried out ngs experiment, conducted data analysis, and revised the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
4398921	25922843	Aparna Ganapathy	2	carried out ngs experiment, conducted data analysis, and revised the paper	carried out ngs experiment, conducted data analysis, and revised the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
4398921	25922843	Arkasubhra Ghosh	2	conceptualized and designed the study, enrolled patients and collected data, and drafted the paper	conceptualized and designed the study, enrolled patients and collected data, and drafted the paper	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Writing - Original Draft	YES
4398921	25922843	Govindasamy Kumaramanickavel	2	critically revised the paper	critically revised the paper	Wrote the paper	Writing - Review & Editing	YES
4398921	25922843	Jemima Jacob	2	carried out ngs experiment, conducted data analysis, and revised the paper	carried out ngs experiment, conducted data analysis, and revised the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
4398921	25922843	Nallathambi Jeyabalan	2	conceptualized and designed the study, enrolled patients and collected data, and drafted the paper	conceptualized and designed the study, enrolled patients and collected data, and drafted the paper	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Writing - Original Draft	YES
4398921	25922843	Rajani Battu	2	enrolled patients and collected clinical data	enrolled patients and collected clinical data	Performed the experiments	Investigation	YES
4398921	25922843	Ramesh Hariharan	2	carried out ngs experiment, conducted data analysis, and revised the paper	carried out ngs experiment, conducted data analysis, and revised the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
4398921	25922843	Ravi Kiran	2	carried out ngs experiment, conducted data analysis, and revised the paper	carried out ngs experiment, conducted data analysis, and revised the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
4398921	25922843	Shuba Krishna	2	carried out ngs experiment, conducted data analysis, and revised the paper	carried out ngs experiment, conducted data analysis, and revised the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
4398921	25922843	Vedam L. Ramprasad	2	carried out ngs experiment, conducted data analysis, and revised the paper	carried out ngs experiment, conducted data analysis, and revised the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
6359194	30654429	B.P.	CRediT	writing-original draft preparation|writing-review and editing	writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
6359194	30654429	B.P.	CRediT	writing-original draft preparation|writing-review and editing	writing-review and editing	Wrote the paper	Writing - Review & Editing	YES
6359194	30654429	C.G.	CRediT	writing-original draft preparation	writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
6359194	30654429	J.D.S.	CRediT	writing-original draft preparation|supervision	writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
6359194	30654429	J.D.S.	CRediT	writing-original draft preparation|supervision	supervision	-	Supervision	YES
6359194	30654429	J.H.H.	CRediT	Conceptualization|writing-original draft preparation|writing-review and editing|supervision	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6359194	30654429	J.H.H.	CRediT	Conceptualization|writing-original draft preparation|writing-review and editing|supervision	writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
6359194	30654429	J.H.H.	CRediT	Conceptualization|writing-original draft preparation|writing-review and editing|supervision	writing-review and editing	Wrote the paper	Writing - Review & Editing	YES
6359194	30654429	J.H.H.	CRediT	Conceptualization|writing-original draft preparation|writing-review and editing|supervision	supervision	-	Supervision	YES
6359194	30654429	J.H.S.	CRediT	writing-original draft preparation|supervision	writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
6359194	30654429	J.H.S.	CRediT	writing-original draft preparation|supervision	supervision	-	Supervision	YES
6359194	30654429	M.W.	CRediT	writing-original draft preparation	writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
5434157	28567045	AB	2	assisted with the performed the initial screening experiment with the|performed the second in depth study|performed all imaging and reconstruction plus most of the modeling work with the|wrote the article with the contributions of the other authors	assisted with the performed the initial screening experiment with the	Performed the experiments	Investigation	YES
5434157	28567045	AB	2	assisted with the performed the initial screening experiment with the|performed the second in depth study|performed all imaging and reconstruction plus most of the modeling work with the|wrote the article with the contributions of the other authors	performed the second in depth study	Performed the experiments	Investigation	YES
5434157	28567045	AB	2	assisted with the performed the initial screening experiment with the|performed the second in depth study|performed all imaging and reconstruction plus most of the modeling work with the|wrote the article with the contributions of the other authors	performed all imaging and reconstruction plus most of the modeling work with the	Performed the experiments|Analyzed the data	Investigation|Methodology|Visualization	YES
5434157	28567045	AB	2	assisted with the performed the initial screening experiment with the|performed the second in depth study|performed all imaging and reconstruction plus most of the modeling work with the|wrote the article with the contributions of the other authors	wrote the article with the contributions of the other authors	Wrote the paper	Writing - Original Draft	YES
5434157	28567045	EM	2	wrote the article with the contributions of the other authors	wrote the article with the contributions of the other authors	Wrote the paper	Writing - Original Draft	YES
5434157	28567045	RR	2	assisted with the performed all imaging and reconstruction plus most of the modeling work with the	assisted with the performed all imaging and reconstruction plus most of the modeling work with the	Performed the experiments|Analyzed the data	Investigation|Methodology|Visualization	YES
5434157	28567045	TH	2	performed the initial screening experiment with the	performed the initial screening experiment with the	Performed the experiments	Investigation	YES
3220631	22050673	CB	2	conceived the study design, analyzed and interpreted the data and wrote the manuscript|contributed to the design of the study and revised the manuscript	conceived the study design, analyzed and interpreted the data and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
3220631	22050673	CB	2	conceived the study design, analyzed and interpreted the data and wrote the manuscript|contributed to the design of the study and revised the manuscript	contributed to the design of the study and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
3220631	22050673	CC	2	participated in the analysis and interpretation of the data and revised the manuscript	participated in the analysis and interpretation of the data and revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
3220631	22050673	EM	2	conceived the study design, analyzed and interpreted the data and wrote the manuscript|contributed to the design of the study and revised the manuscript	conceived the study design, analyzed and interpreted the data and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
3220631	22050673	EM	2	conceived the study design, analyzed and interpreted the data and wrote the manuscript|contributed to the design of the study and revised the manuscript	contributed to the design of the study and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
3220631	22050673	JB	2	conceived the study design, analyzed and interpreted the data and wrote the manuscript|contributed to the design of the study and revised the manuscript	conceived the study design, analyzed and interpreted the data and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
3220631	22050673	JB	2	conceived the study design, analyzed and interpreted the data and wrote the manuscript|contributed to the design of the study and revised the manuscript	contributed to the design of the study and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
3220631	22050673	JN	2	participated in the analysis and interpretation of the data and revised the manuscript	participated in the analysis and interpretation of the data and revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
3220631	22050673	KC	2	conceived the study design, analyzed and interpreted the data and wrote the manuscript|participated in the analysis and interpretation of the data and revised the manuscript	conceived the study design, analyzed and interpreted the data and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
3220631	22050673	KC	2	conceived the study design, analyzed and interpreted the data and wrote the manuscript|participated in the analysis and interpretation of the data and revised the manuscript	participated in the analysis and interpretation of the data and revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
3220631	22050673	NF	2	participated in the analysis and interpretation of the data and revised the manuscript	participated in the analysis and interpretation of the data and revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
3220631	22050673	RH	2	participated in the analysis and interpretation of the data and revised the manuscript	participated in the analysis and interpretation of the data and revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
3223126	22029667	JVL	2	made substantial contributions to data interpretation and revising of the manuscript	made substantial contributions to data interpretation and revising of the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
3223126	22029667	MAA	2	was involved in the drafting of the manuscript and substantially contributed to data interpretation	was involved in the drafting of the manuscript and substantially contributed to data interpretation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3223126	22029667	OA	2	contributed to the conception and design of the study, data collection, analysis and its interpretation, as well as drafting of the initial manuscript	contributed to the conception and design of the study, data collection, analysis and its interpretation, as well as drafting of the initial manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
3223126	22029667	RA	2	substantially contributed to the conception and design of the study, as well as to data interpretation	substantially contributed to the conception and design of the study, as well as to data interpretation	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Methodology|Resources	YES
4398381	25874883	AA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398381	25874883	AA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398381	25874883	AA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398381	25874883	AA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398381	25874883	AG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398381	25874883	AG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398381	25874883	AG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398381	25874883	CF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398381	25874883	CF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398381	25874883	CF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398381	25874883	CF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398381	25874883	EL	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398381	25874883	EL	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5001245	27556804	All authors	2	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5001245	27556804	HE	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5001245	27556804	LL	2	conceived the project|provided statistical support	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5001245	27556804	LL	2	conceived the project|provided statistical support	provided statistical support	Analyzed the data	Formal analysis	YES
5001245	27556804	PZ	2	conducted the analysis	conducted the analysis	Performed the experiments	Investigation	YES
5001245	27556804	XX	2	performed the sequencing experiment	performed the sequencing experiment	Performed the experiments	Investigation	YES
5001245	27556804	YH	2	conducted the analysis|wrote the manuscript	conducted the analysis	Performed the experiments	Investigation	YES
5001245	27556804	YH	2	conducted the analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5001245	27556804	YL	2	conceived the project|wrote the manuscript	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5001245	27556804	YL	2	conceived the project|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5606940	28779336	ABP	2	contributed to the collection of data from diabetes mellitus patients, carried out the retinographies, interpreted the research data, assisted in writing the manuscript and contributed to the final approval of the version sent for publication	contributed to the collection of data from diabetes mellitus patients, carried out the retinographies, interpreted the research data, assisted in writing the manuscript and contributed to the final approval of the version sent for publication	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft	YES
5606940	28779336	JM	2	contributed to the study design and the statistical analysis, assisted in the research data interpretation, contributed to the interpretation of the study findings and contributed to the final approval of the version sent for publication	contributed to the study design and the statistical analysis, assisted in the research data interpretation, contributed to the interpretation of the study findings and contributed to the final approval of the version sent for publication	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Methodology|Resources	YES
5606940	28779336	MBB	2	contributed to study conception and design, contributed to the ophthalmological data collection, diagnosed diabetic macular edema, performed the electrophysiology procedures, elaborated on the discussion, conducted a critical review and contributed to the final approval of the version sent for publication	contributed to study conception and design, contributed to the ophthalmological data collection, diagnosed diabetic macular edema, performed the electrophysiology procedures, elaborated on the discussion, conducted a critical review and contributed to the final approval of the version sent for publication	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceptualization|Investigation|Methodology|Resources	YES
5606940	28779336	PRA	2	contributed to the study conception and design, collected research data, reviewed the statistical analyses, elaborated on the discussion, wrote and edited the manuscript and contributed to the final approval of the version sent for publication	contributed to the study conception and design, collected research data, reviewed the statistical analyses, elaborated on the discussion, wrote and edited the manuscript and contributed to the final approval of the version sent for publication	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
6359235	30641992	C.S.	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
6359235	30641992	F.G.	CRediT	Resources|Writing-review & editing	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6359235	30641992	F.G.	CRediT	Resources|Writing-review & editing	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6359235	30641992	G.I.	CRediT	Conceptualization|Methodology|Formal analysis|Investigation|Resources|Data curation|Writing-original draft preparation|Writing-review & editing|Visualization|Supervision	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6359235	30641992	G.I.	CRediT	Conceptualization|Methodology|Formal analysis|Investigation|Resources|Data curation|Writing-original draft preparation|Writing-review & editing|Visualization|Supervision	Methodology	Performed the experiments	Methodology	YES
6359235	30641992	G.I.	CRediT	Conceptualization|Methodology|Formal analysis|Investigation|Resources|Data curation|Writing-original draft preparation|Writing-review & editing|Visualization|Supervision	Formal analysis	Analyzed the data	Formal analysis	YES
6359235	30641992	G.I.	CRediT	Conceptualization|Methodology|Formal analysis|Investigation|Resources|Data curation|Writing-original draft preparation|Writing-review & editing|Visualization|Supervision	Investigation	Performed the experiments	Investigation	YES
6359235	30641992	G.I.	CRediT	Conceptualization|Methodology|Formal analysis|Investigation|Resources|Data curation|Writing-original draft preparation|Writing-review & editing|Visualization|Supervision	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6359235	30641992	G.I.	CRediT	Conceptualization|Methodology|Formal analysis|Investigation|Resources|Data curation|Writing-original draft preparation|Writing-review & editing|Visualization|Supervision	Data curation	Analyzed the data	Data curation	YES
6359235	30641992	G.I.	CRediT	Conceptualization|Methodology|Formal analysis|Investigation|Resources|Data curation|Writing-original draft preparation|Writing-review & editing|Visualization|Supervision	Writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
6359235	30641992	G.I.	CRediT	Conceptualization|Methodology|Formal analysis|Investigation|Resources|Data curation|Writing-original draft preparation|Writing-review & editing|Visualization|Supervision	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6359235	30641992	G.I.	CRediT	Conceptualization|Methodology|Formal analysis|Investigation|Resources|Data curation|Writing-original draft preparation|Writing-review & editing|Visualization|Supervision	Visualization	Analyzed the data	Visualization	YES
6359235	30641992	G.I.	CRediT	Conceptualization|Methodology|Formal analysis|Investigation|Resources|Data curation|Writing-original draft preparation|Writing-review & editing|Visualization|Supervision	Supervision	-	Supervision	YES
6359235	30641992	G.R.	CRediT	Data curation|Writing-review & editing|Supervision	Data curation	Analyzed the data	Data curation	YES
6359235	30641992	G.R.	CRediT	Data curation|Writing-review & editing|Supervision	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6359235	30641992	G.R.	CRediT	Data curation|Writing-review & editing|Supervision	Supervision	-	Supervision	YES
6359235	30641992	M.D.L.	CRediT	Software|Validation|Data curation	Software	Contributed reagents/materials/analysis tools	Software	YES
6359235	30641992	M.D.L.	CRediT	Software|Validation|Data curation	Validation	Performed the experiments	Validation	YES
6359235	30641992	M.D.L.	CRediT	Software|Validation|Data curation	Data curation	Analyzed the data	Data curation	YES
6359235	30641992	M.G.G.	CRediT	Conceptualization|Investigation|Writing-original draft preparation|Writing-review & editing|Visualization	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6359235	30641992	M.G.G.	CRediT	Conceptualization|Investigation|Writing-original draft preparation|Writing-review & editing|Visualization	Investigation	Performed the experiments	Investigation	YES
6359235	30641992	M.G.G.	CRediT	Conceptualization|Investigation|Writing-original draft preparation|Writing-review & editing|Visualization	Writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
6359235	30641992	M.G.G.	CRediT	Conceptualization|Investigation|Writing-original draft preparation|Writing-review & editing|Visualization	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6359235	30641992	M.G.G.	CRediT	Conceptualization|Investigation|Writing-original draft preparation|Writing-review & editing|Visualization	Visualization	Analyzed the data	Visualization	YES
3228661	22078415	AK	2	reviewed the protocol, interpreted data, and participated in the revisions of the paper	reviewed the protocol, interpreted data, and participated in the revisions of the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
3228661	22078415	JE	2	reviewed the protocol, interpreted data, and participated in the revisions of the paper	reviewed the protocol, interpreted data, and participated in the revisions of the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
3228661	22078415	JW	2	reviewed the protocol, interpreted data, and participated in the revisions of the paper	reviewed the protocol, interpreted data, and participated in the revisions of the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
3228661	22078415	PJ	2	developed the protocol, conducted the field study, interpreted data, and revised the paper	developed the protocol, conducted the field study, interpreted data, and revised the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
3228661	22078415	PP	2	assisted with protocol development and approval, participant recruitment and paper revision	assisted with protocol development and approval, participant recruitment and paper revision	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
3228661	22078415	RD	2	supervised statistical analysis, interpretation of data and revisions of the paper	supervised statistical analysis, interpretation of data and revisions of the paper	Analyzed the data|Wrote the paper	Formal analysis|Supervision|Writing - Review & Editing	YES
3228661	22078415	YJ	2	conducted lab analyses, interpreted lab data, and revised the paper	conducted lab analyses, interpreted lab data, and revised the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
5434160	28567046	All authors	PLoS52	have read and approved the final draft	have read and approved the final draft	Wrote the paper	Writing - Original Draft	YES
5434160	28567046	BZ	PLoS52	contribute reagents/materials and interpretation of the results	contribute reagents/materials and interpretation of the results	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5434160	28567046	CX	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5434160	28567046	FW	PLoS52	conceived and designed the research|performed the experiments|generated the pictures|wrote and revised the manuscript	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5434160	28567046	FW	PLoS52	conceived and designed the research|performed the experiments|generated the pictures|wrote and revised the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5434160	28567046	FW	PLoS52	conceived and designed the research|performed the experiments|generated the pictures|wrote and revised the manuscript	generated the pictures	Performed the experiments	Investigation|Visualization	YES
5434160	28567046	FW	PLoS52	conceived and designed the research|performed the experiments|generated the pictures|wrote and revised the manuscript	wrote and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5434160	28567046	HS	PLoS52	generated the pictures	generated the pictures	Performed the experiments	Investigation|Visualization	YES
5434160	28567046	JD	PLoS52	contribute reagents/materials and interpretation of the results	contribute reagents/materials and interpretation of the results	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5434160	28567046	JZ	PLoS52	conceived and designed the research|performed the experiments|wrote and revised the manuscript	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5434160	28567046	JZ	PLoS52	conceived and designed the research|performed the experiments|wrote and revised the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5434160	28567046	JZ	PLoS52	conceived and designed the research|performed the experiments|wrote and revised the manuscript	wrote and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5434160	28567046	LG	PLoS52	contribute reagents/materials and interpretation of the results	contribute reagents/materials and interpretation of the results	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5434160	28567046	LW	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5434160	28567046	ML	PLoS52	generated the pictures	generated the pictures	Performed the experiments	Investigation|Visualization	YES
5434160	28567046	YS	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5434160	28567046	ZZ	PLoS52	conceived and designed the research|wrote and revised the manuscript	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5434160	28567046	ZZ	PLoS52	conceived and designed the research|wrote and revised the manuscript	wrote and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4398382	25876178	FY	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4398382	25876178	FY	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4398382	25876178	FY	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398382	25876178	SYJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398382	25876178	SYJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4398382	25876178	SYJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398382	25876178	WJ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4398382	25876178	WJ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4398382	25876178	WJ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398382	25876178	WXJ	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4398382	25876178	WXJ	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398382	25876178	XH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398382	25876178	XH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398382	25876178	XH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398382	25876178	XH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398382	25876178	XH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3228719	22085598	GUvZ	2	wrote the draft manuscript	wrote the draft manuscript	Wrote the paper	Writing - Original Draft	YES
3228719	22085598	HR	2	assisted with patient selection and recruitment|assisted with writing, contextualizing and revising the final manuscript	assisted with patient selection and recruitment	Performed the experiments	Investigation	YES
3228719	22085598	HR	2	assisted with patient selection and recruitment|assisted with writing, contextualizing and revising the final manuscript	assisted with writing, contextualizing and revising the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3228719	22085598	JJN	2	assisted with patient selection and recruitment|assisted with writing, contextualizing and revising the final manuscript	assisted with patient selection and recruitment	Performed the experiments	Investigation	YES
3228719	22085598	JJN	2	assisted with patient selection and recruitment|assisted with writing, contextualizing and revising the final manuscript	assisted with writing, contextualizing and revising the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3228719	22085598	MFC	2	provided oversight over the study|assisted with writing, contextualizing and revising the final manuscript	provided oversight over the study	-	Supervision	YES
3228719	22085598	MFC	2	provided oversight over the study|assisted with writing, contextualizing and revising the final manuscript	assisted with writing, contextualizing and revising the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5001246	27556634	MZ	2	conceived the project|collected the data and carried out all the analyses|finalized the manuscript	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5001246	27556634	MZ	2	conceived the project|collected the data and carried out all the analyses|finalized the manuscript	collected the data and carried out all the analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5001246	27556634	MZ	2	conceived the project|collected the data and carried out all the analyses|finalized the manuscript	finalized the manuscript	Wrote the paper	Writing - Review & Editing	YES
5001246	27556634	ZZ	2	conceived the project|finalized the manuscript	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5001246	27556634	ZZ	2	conceived the project|finalized the manuscript	finalized the manuscript	Wrote the paper	Writing - Review & Editing	YES
6359248	30669699	C.A.C.	CRediT	formal analysis|investigation|resources|data curation|writing--original draft preparation|visualization	formal analysis	Analyzed the data	Formal analysis	YES
6359248	30669699	C.A.C.	CRediT	formal analysis|investigation|resources|data curation|writing--original draft preparation|visualization	investigation	Performed the experiments	Investigation	YES
6359248	30669699	C.A.C.	CRediT	formal analysis|investigation|resources|data curation|writing--original draft preparation|visualization	resources	Contributed reagents/materials/analysis tools	Resources	YES
6359248	30669699	C.A.C.	CRediT	formal analysis|investigation|resources|data curation|writing--original draft preparation|visualization	data curation	Analyzed the data	Data curation	YES
6359248	30669699	C.A.C.	CRediT	formal analysis|investigation|resources|data curation|writing--original draft preparation|visualization	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6359248	30669699	C.A.C.	CRediT	formal analysis|investigation|resources|data curation|writing--original draft preparation|visualization	visualization	Analyzed the data	Visualization	YES
6359248	30669699	D.R.	CRediT	investigation|resources	investigation	Performed the experiments	Investigation	YES
6359248	30669699	D.R.	CRediT	investigation|resources	resources	Contributed reagents/materials/analysis tools	Resources	YES
6359248	30669699	E.V.F.	CRediT	investigation|resources|writing--original draft preparation	investigation	Performed the experiments	Investigation	YES
6359248	30669699	E.V.F.	CRediT	investigation|resources|writing--original draft preparation	resources	Contributed reagents/materials/analysis tools	Resources	YES
6359248	30669699	E.V.F.	CRediT	investigation|resources|writing--original draft preparation	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6359248	30669699	G.V.	CRediT	investigation	investigation	Performed the experiments	Investigation	YES
6359248	30669699	I.M.	CRediT	validation|supervision|funding acquisition	validation	Performed the experiments	Validation	YES
6359248	30669699	I.M.	CRediT	validation|supervision|funding acquisition	supervision	-	Supervision	YES
6359248	30669699	I.M.	CRediT	validation|supervision|funding acquisition	funding acquisition	-	Funding acquisition	YES
6359248	30669699	M.C.	CRediT	The following statements should be used conceptualization|methodology|validation|writing--original draft preparation|writing--review and editing|visualization|supervision|project administration|funding acquisition	The following statements should be used conceptualization	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
6359248	30669699	M.C.	CRediT	The following statements should be used conceptualization|methodology|validation|writing--original draft preparation|writing--review and editing|visualization|supervision|project administration|funding acquisition	methodology	Performed the experiments	Methodology	YES
6359248	30669699	M.C.	CRediT	The following statements should be used conceptualization|methodology|validation|writing--original draft preparation|writing--review and editing|visualization|supervision|project administration|funding acquisition	validation	Performed the experiments	Validation	YES
6359248	30669699	M.C.	CRediT	The following statements should be used conceptualization|methodology|validation|writing--original draft preparation|writing--review and editing|visualization|supervision|project administration|funding acquisition	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6359248	30669699	M.C.	CRediT	The following statements should be used conceptualization|methodology|validation|writing--original draft preparation|writing--review and editing|visualization|supervision|project administration|funding acquisition	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6359248	30669699	M.C.	CRediT	The following statements should be used conceptualization|methodology|validation|writing--original draft preparation|writing--review and editing|visualization|supervision|project administration|funding acquisition	visualization	Analyzed the data	Visualization	YES
6359248	30669699	M.C.	CRediT	The following statements should be used conceptualization|methodology|validation|writing--original draft preparation|writing--review and editing|visualization|supervision|project administration|funding acquisition	supervision	-	Supervision	YES
6359248	30669699	M.C.	CRediT	The following statements should be used conceptualization|methodology|validation|writing--original draft preparation|writing--review and editing|visualization|supervision|project administration|funding acquisition	project administration	-	Project administration	YES
6359248	30669699	M.C.	CRediT	The following statements should be used conceptualization|methodology|validation|writing--original draft preparation|writing--review and editing|visualization|supervision|project administration|funding acquisition	funding acquisition	-	Funding acquisition	YES
6359248	30669699	M.D.	CRediT	investigation	investigation	Performed the experiments	Investigation	YES
6359248	30669699	M.S.	CRediT	validation|writing--review and editing|funding acquisition	validation	Performed the experiments	Validation	YES
6359248	30669699	M.S.	CRediT	validation|writing--review and editing|funding acquisition	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6359248	30669699	M.S.	CRediT	validation|writing--review and editing|funding acquisition	funding acquisition	-	Funding acquisition	YES
6359248	30669699	V.E.	CRediT	writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6359248	30669699	V.S.	CRediT	investigation|writing--review and editing|funding acquisition	investigation	Performed the experiments	Investigation	YES
6359248	30669699	V.S.	CRediT	investigation|writing--review and editing|funding acquisition	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6359248	30669699	V.S.	CRediT	investigation|writing--review and editing|funding acquisition	funding acquisition	-	Funding acquisition	YES
3248834	22098625	CH	2	wrote the section on cervical cancer, as well as compiling references	wrote the section on cervical cancer, as well as compiling references	Wrote the paper	Writing - Original Draft	YES
3248834	22098625	JG	2	conducted the literature search, summarized the articles and wrote the initial draft	conducted the literature search, summarized the articles and wrote the initial draft	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5434166	28567049	All authors	2	approved the manuscript	approved the manuscript	-	-	NO
5434166	28567049	DG	2	developed the mapping population and participated in interpreting results and writing the manuscript	developed the mapping population and participated in interpreting results and writing the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5434166	28567049	HL	2	analyzed sequence data and performed qtl analysis	analyzed sequence data and performed qtl analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5434166	28567049	NL	2	analyzed sequence data and performed qtl analysis	analyzed sequence data and performed qtl analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5434166	28567049	XW	2	collected phenotypic data|analyzed sequence data and performed qtl analysis	collected phenotypic data	Performed the experiments	Investigation	YES
5434166	28567049	XW	2	collected phenotypic data|analyzed sequence data and performed qtl analysis	analyzed sequence data and performed qtl analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5434166	28567049	XY	2	analyzed sequence data and performed qtl analysis	analyzed sequence data and performed qtl analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5434166	28567049	XZ	2	collected phenotypic data|analyzed sequence data and performed qtl analysis	collected phenotypic data	Performed the experiments	Investigation	YES
5434166	28567049	XZ	2	collected phenotypic data|analyzed sequence data and performed qtl analysis	analyzed sequence data and performed qtl analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5434166	28567049	YJ	2	designed the experiments and led writing of the manuscript	designed the experiments and led writing of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5434166	28567049	ZP	2	analyzed sequence data and performed qtl analysis	analyzed sequence data and performed qtl analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5780760	22498052	AR	2	were involved in developing diary cards, consent forms and information sheets and collation and review of data	were involved in developing diary cards, consent forms and information sheets and collation and review of data	-	-	NO
5780760	22498052	All authors	2	were involved in the development of the study design|revised the manuscript critically and approved the final version that was submitted	were involved in the development of the study design	Conceived and designed the experiments	Methodology	YES
5780760	22498052	All authors	2	were involved in the development of the study design|revised the manuscript critically and approved the final version that was submitted	revised the manuscript critically and approved the final version that was submitted	Wrote the paper	Writing - Review & Editing	YES
5780760	22498052	BF	2	cleaned and analyzed the data and led the writing of the manuscript	cleaned and analyzed the data and led the writing of the manuscript	Analyzed the data|Wrote the paper	Data curation|Formal analysis|Writing - Original Draft	YES
5780760	22498052	CJ	2	were involved in developing diary cards, consent forms and information sheets and collation and review of data	were involved in developing diary cards, consent forms and information sheets and collation and review of data	-	-	NO
5780760	22498052	FWT	2	cleaned and analyzed the data and led the writing of the manuscript	cleaned and analyzed the data and led the writing of the manuscript	Analyzed the data|Wrote the paper	Data curation|Formal analysis|Writing - Original Draft	YES
5780760	22498052	GF	2	cleaned and analyzed the data and led the writing of the manuscript	cleaned and analyzed the data and led the writing of the manuscript	Analyzed the data|Wrote the paper	Data curation|Formal analysis|Writing - Original Draft	YES
5780760	22498052	JVB	2	were involved in developing diary cards, consent forms and information sheets and collation and review of data	were involved in developing diary cards, consent forms and information sheets and collation and review of data	-	-	NO
5780760	22498052	PVB	2	cleaned and analyzed the data and led the writing of the manuscript	cleaned and analyzed the data and led the writing of the manuscript	Analyzed the data|Wrote the paper	Data curation|Formal analysis|Writing - Original Draft	YES
6359283	30621239	H.H.	CRediT	software	software	Contributed reagents/materials/analysis tools	Software	YES
6359283	30621239	J.W.	CRediT	writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6359283	30621239	L.L.	CRediT	methodology|writing--original draft preparation	methodology	Performed the experiments	Methodology	YES
6359283	30621239	L.L.	CRediT	methodology|writing--original draft preparation	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6359283	30621239	L.Y.	CRediT	Conceptualization|methodology|writing--original draft preparation	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6359283	30621239	L.Y.	CRediT	Conceptualization|methodology|writing--original draft preparation	methodology	Performed the experiments	Methodology	YES
6359283	30621239	L.Y.	CRediT	Conceptualization|methodology|writing--original draft preparation	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6359283	30621239	P.L.	CRediT	Conceptualization|writing--review and editing|supervision|project administration	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6359283	30621239	P.L.	CRediT	Conceptualization|writing--review and editing|supervision|project administration	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6359283	30621239	P.L.	CRediT	Conceptualization|writing--review and editing|supervision|project administration	supervision	-	Supervision	YES
6359283	30621239	P.L.	CRediT	Conceptualization|writing--review and editing|supervision|project administration	project administration	-	Project administration	YES
4398383	25874375	CLL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398383	25874375	CLL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398383	25874375	CLL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398383	25874375	JJJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398383	25874375	JJJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398383	25874375	JJJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398383	25874375	JJJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398383	25874375	KGB	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398383	25874375	MDF	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398383	25874375	MDF	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398383	25874375	MDF	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398383	25874375	SWG	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5001247	27557076	All authors	2	are involved in the drafting and revisions of the manuscript	are involved in the drafting and revisions of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5001247	27557076	FZ	2	developed the distance method and performed the statistical analyses	developed the distance method and performed the statistical analyses	Performed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5001247	27557076	JYC	2	conceived the initial work and designed the method	conceived the initial work and designed the method	Conceived and designed the experiments|Performed the experiments	Conceptualization|Methodology	YES
3253672	22078463	DC	2	reviewed the drafts and gave comments	reviewed the drafts and gave comments	Wrote the paper	Writing - Original Draft	YES
3253672	22078463	HB	2	reviewed the drafts and gave comments	reviewed the drafts and gave comments	Wrote the paper	Writing - Original Draft	YES
3253672	22078463	JGM	2	reviewed the drafts and gave comments	reviewed the drafts and gave comments	Wrote the paper	Writing - Original Draft	YES
3253672	22078463	MdB	2	reviewed the drafts and gave comments	reviewed the drafts and gave comments	Wrote the paper	Writing - Original Draft	YES
3253672	22078463	PO	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
3253672	22078463	RB	2	reviewed the drafts and gave comments	reviewed the drafts and gave comments	Wrote the paper	Writing - Original Draft	YES
4398939	25922842	Liang Liang	2	contributed equally to this work	contributed equally to this work	-	-	NO
4398939	25922842	Runguang Li	2	contributed equally to this work	contributed equally to this work	-	-	NO
5434454	28567051	AG-V	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5434454	28567051	AH-E	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5434454	28567051	JL-B	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5434454	28567051	RP-F	2	designed and performed experiments, collected, and interpreted data|wrote the manuscript	designed and performed experiments, collected, and interpreted data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5434454	28567051	RP-F	2	designed and performed experiments, collected, and interpreted data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5434454	28567051	SE-R	2	performed experiments and provided technical support	performed experiments and provided technical support	Performed the experiments	Investigation	YES
6359315	30583524	A.D.	CRediT	Resources|Writing--review & editing	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6359315	30583524	A.D.	CRediT	Resources|Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6359315	30583524	A.F.	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
6359315	30583524	B.S.	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
6359315	30583524	F.I.	CRediT	Supervision|Writing--review & editing	Supervision	-	Supervision	YES
6359315	30583524	F.I.	CRediT	Supervision|Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6359315	30583524	F.P.N.	CRediT	Formal analysis|Validation|Writing--review & editing	Formal analysis	Analyzed the data	Formal analysis	YES
6359315	30583524	F.P.N.	CRediT	Formal analysis|Validation|Writing--review & editing	Validation	Performed the experiments	Validation	YES
6359315	30583524	F.P.N.	CRediT	Formal analysis|Validation|Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6359315	30583524	F.V.	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
6359315	30583524	G.C.	CRediT	Conceptualization|Methodology|Validation|Writing--original draft	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6359315	30583524	G.C.	CRediT	Conceptualization|Methodology|Validation|Writing--original draft	Methodology	Performed the experiments	Methodology	YES
6359315	30583524	G.C.	CRediT	Conceptualization|Methodology|Validation|Writing--original draft	Validation	Performed the experiments	Validation	YES
6359315	30583524	G.C.	CRediT	Conceptualization|Methodology|Validation|Writing--original draft	Writing--original draft	Wrote the paper	Writing - Original Draft	YES
6359315	30583524	G.F.G.	CRediT	Resources|Supervision|Writing--review & editing	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6359315	30583524	G.F.G.	CRediT	Resources|Supervision|Writing--review & editing	Supervision	-	Supervision	YES
6359315	30583524	G.F.G.	CRediT	Resources|Supervision|Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6359315	30583524	L.L.	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
6359315	30583524	M.C.	CRediT	Investigation|Visualization	Investigation	Performed the experiments	Investigation	YES
6359315	30583524	M.C.	CRediT	Investigation|Visualization	Visualization	Analyzed the data	Visualization	YES
6359315	30583524	M.L.G.	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
6359315	30583524	O.V.	CRediT	Conceptualization|Formal analysis|Methodology|Visualization	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6359315	30583524	O.V.	CRediT	Conceptualization|Formal analysis|Methodology|Visualization	Formal analysis	Analyzed the data	Formal analysis	YES
6359315	30583524	O.V.	CRediT	Conceptualization|Formal analysis|Methodology|Visualization	Methodology	Performed the experiments	Methodology	YES
6359315	30583524	O.V.	CRediT	Conceptualization|Formal analysis|Methodology|Visualization	Visualization	Analyzed the data	Visualization	YES
6359315	30583524	S.H.	CRediT	Resources|Writing--review & editing	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6359315	30583524	S.H.	CRediT	Resources|Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
3267676	22182532	CM	2	participated in the design and coordination of the study and critically reviewed the manuscript	participated in the design and coordination of the study and critically reviewed the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Review & Editing	YES
3267676	22182532	IC	2	participated in the design and coordination of the study and critically reviewed the manuscript	participated in the design and coordination of the study and critically reviewed the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Review & Editing	YES
3267676	22182532	JJD	2	contributed to the design of the study, performed the statistical analysis and wrote the first draft of the manuscript	contributed to the design of the study, performed the statistical analysis and wrote the first draft of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3267676	22182532	MP	2	contributed to the design of the study, performed the statistical analysis and wrote the first draft of the manuscript	contributed to the design of the study, performed the statistical analysis and wrote the first draft of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4398385	25874750	AB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398385	25874750	DP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398385	25874750	DP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398385	25874750	DP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398385	25874750	FB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398385	25874750	FB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398385	25874750	FB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398385	25874750	FB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398385	25874750	JH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398385	25874750	JH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398385	25874750	JH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398385	25874750	JPS	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4398385	25874750	ND	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5001248	27556803	AF	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5001248	27556803	All authors	PLoS52	contributed to the core elements of this work	contributed to the core elements of this work	-	-	NO
5001248	27556803	DA	PLoS52	initiated the project|developed the lcs algorithm|developed the compression algorithm|coordinated the overall project|prepared the final manuscript	initiated the project	Conceived and designed the experiments	Conceptualization	YES
5001248	27556803	DA	PLoS52	initiated the project|developed the lcs algorithm|developed the compression algorithm|coordinated the overall project|prepared the final manuscript	developed the lcs algorithm	Contributed reagents/materials/analysis tools	Software	YES
5001248	27556803	DA	PLoS52	initiated the project|developed the lcs algorithm|developed the compression algorithm|coordinated the overall project|prepared the final manuscript	developed the compression algorithm	Contributed reagents/materials/analysis tools	Software	YES
5001248	27556803	DA	PLoS52	initiated the project|developed the lcs algorithm|developed the compression algorithm|coordinated the overall project|prepared the final manuscript	coordinated the overall project	-	Project administration	YES
5001248	27556803	DA	PLoS52	initiated the project|developed the lcs algorithm|developed the compression algorithm|coordinated the overall project|prepared the final manuscript	prepared the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5001248	27556803	RB	PLoS52	developed the lcs algorithm|developed the compression algorithm|implemented the lpf and compression methods|performed the experiments|prepared the final manuscript	developed the lcs algorithm	Contributed reagents/materials/analysis tools	Software	YES
5001248	27556803	RB	PLoS52	developed the lcs algorithm|developed the compression algorithm|implemented the lpf and compression methods|performed the experiments|prepared the final manuscript	developed the compression algorithm	Contributed reagents/materials/analysis tools	Software	YES
5001248	27556803	RB	PLoS52	developed the lcs algorithm|developed the compression algorithm|implemented the lpf and compression methods|performed the experiments|prepared the final manuscript	implemented the lpf and compression methods	Performed the experiments	Investigation	YES
5001248	27556803	RB	PLoS52	developed the lcs algorithm|developed the compression algorithm|implemented the lpf and compression methods|performed the experiments|prepared the final manuscript	performed the experiments	Performed the experiments	Investigation	YES
5001248	27556803	RB	PLoS52	developed the lcs algorithm|developed the compression algorithm|implemented the lpf and compression methods|performed the experiments|prepared the final manuscript	prepared the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5001248	27556803	TA	PLoS52	developed the lcs algorithm	developed the lcs algorithm	Contributed reagents/materials/analysis tools	Software	YES
5435750	28572813	NC	PLoS52	planned and designed the studies|performed experiments|analyzed the data|wrote the manuscript	planned and designed the studies	Conceived and designed the experiments	Conceptualization|Methodology	YES
5435750	28572813	NC	PLoS52	planned and designed the studies|performed experiments|analyzed the data|wrote the manuscript	performed experiments	Performed the experiments	Investigation	YES
5435750	28572813	NC	PLoS52	planned and designed the studies|performed experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5435750	28572813	NC	PLoS52	planned and designed the studies|performed experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5435750	28572813	X-GX	PLoS52	planned and designed the studies|analyzed the data|wrote the manuscript	planned and designed the studies	Conceived and designed the experiments	Conceptualization|Methodology	YES
5435750	28572813	X-GX	PLoS52	planned and designed the studies|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5435750	28572813	X-GX	PLoS52	planned and designed the studies|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5435750	28572813	Z-HY	PLoS52	planned and designed the studies|performed experiments|analyzed the data	planned and designed the studies	Conceived and designed the experiments	Conceptualization|Methodology	YES
5435750	28572813	Z-HY	PLoS52	planned and designed the studies|performed experiments|analyzed the data	performed experiments	Performed the experiments	Investigation	YES
5435750	28572813	Z-HY	PLoS52	planned and designed the studies|performed experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
6359353	30621141	F.-m.L.	2	substantially helped in the animal experiments	substantially helped in the animal experiments	Performed the experiments	Investigation	YES
6359353	30621141	F.S.	2	helped in the analysis of data	helped in the analysis of data	Analyzed the data	Formal analysis	YES
6359353	30621141	G.W.	2	substantively revised it	substantively revised it	Wrote the paper	Writing - Review & Editing	YES
6359353	30621141	J.W.	2	substantially helped in the animal experiments	substantially helped in the animal experiments	Performed the experiments	Investigation	YES
6359353	30621141	L.-l.F.	2	helped in the analysis of data	helped in the analysis of data	Analyzed the data	Formal analysis	YES
6359353	30621141	L.-q.C.	2	were responsible for the acquisition of data	were responsible for the acquisition of data	Performed the experiments	Investigation	YES
6359353	30621141	S.-j.C.	2	established the tumor-bearing animal model	established the tumor-bearing animal model	Performed the experiments	Methodology	YES
6359353	30621141	W.-y.L.	2	substantively revised it	substantively revised it	Wrote the paper	Writing - Review & Editing	YES
6359353	30621141	Y.L.	2	designed the work	designed the work	Conceived and designed the experiments	-	YES
6359353	30621141	Z.-g.H.	2	were responsible for the acquisition of data	were responsible for the acquisition of data	Performed the experiments	Investigation	YES
6359353	30621141	Z.-p.L.	2	drafted the work	drafted the work	Wrote the paper	Writing - Original Draft	YES
3271988	22182588	BL	2	developed the method, completed data analysis, and drafted and revised the manuscript	developed the method, completed data analysis, and drafted and revised the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
3271988	22182588	NW	2	contributed to developing the method, developing data for the bidii case study, and revising the report	contributed to developing the method, developing data for the bidii case study, and revising the report	Performed the experiments|Contributed reagents/materials/analysis tools	Methodology|Resources	YES
4398947	25922834	Allen F. Ryan	2	supported editing the paper and assisted with data analysis and interpretation	supported editing the paper and assisted with data analysis and interpretation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4398947	25922834	Anke Leichtle	2	supervised the project, designed experiments, performed experiments, and contributed to writing the paper	supervised the project, designed experiments, performed experiments, and contributed to writing the paper	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Supervision|Writing - Original Draft	YES
4398947	25922834	Anna Sophie Hoffmann	2	contributed to analyzing data	contributed to analyzing data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
4398947	25922834	Barbara Wollenberg	2	supported editing the paper and assisted with data analysis and interpretation	supported editing the paper and assisted with data analysis and interpretation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4398947	25922834	Christin Klenke	2	performed microarray and protein interaction data	performed microarray and protein interaction data	Performed the experiments	Investigation	YES
4398947	25922834	Holger Sudhoff	2	supported editing the paper and assisted with data analysis and interpretation	supported editing the paper and assisted with data analysis and interpretation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4398947	25922834	Joerg Ebmeyer	2	contributed to writing the paper	contributed to writing the paper	Wrote the paper	Writing - Original Draft	YES
4398947	25922834	Karl-Ludwig Bruchhage	2	contributed to analyzing data	contributed to analyzing data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
4398947	25922834	Markus Daerr	2	performed qpcr	performed qpcr	Performed the experiments	Investigation	YES
4398386	25874643	HCK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Conducted field surveillance	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398386	25874643	HCK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Conducted field surveillance	Analyzed the data	Analyzed the data	Formal analysis	YES
4398386	25874643	HCK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Conducted field surveillance	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398386	25874643	HCK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Conducted field surveillance	Conducted field surveillance	Performed the experiments	Investigation	YES
4398386	25874643	JAK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398386	25874643	JWS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398386	25874643	JWS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398386	25874643	JWS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398386	25874643	JWS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398386	25874643	PVN	PLoS5	Conducted field surveillance	Conducted field surveillance	Performed the experiments	Investigation	YES
4398386	25874643	STC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398386	25874643	SYL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398386	25874643	TAK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Conducted field surveillance	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398386	25874643	TAK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Conducted field surveillance	Analyzed the data	Analyzed the data	Formal analysis	YES
4398386	25874643	TAK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Conducted field surveillance	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398386	25874643	TAK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Conducted field surveillance	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398386	25874643	TAK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Conducted field surveillance	Conducted field surveillance	Performed the experiments	Investigation	YES
4398386	25874643	WKK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
3281784	22177276	BC	2	wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
3281784	22177276	FN	2	designed the study, evaluated interim findings, and assisted in revising subsequent versions of the manuscript	designed the study, evaluated interim findings, and assisted in revising subsequent versions of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
3281784	22177276	HGK	2	designed the study, evaluated interim findings, and assisted in revising subsequent versions of the manuscript	designed the study, evaluated interim findings, and assisted in revising subsequent versions of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
3281784	22177276	LS	2	wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
3281784	22177276	TB	2	designed the study, evaluated interim findings, and assisted in revising subsequent versions of the manuscript	designed the study, evaluated interim findings, and assisted in revising subsequent versions of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5002099	27565432	AJS	2	characterized the clinical and genetic data of the icf patient	characterized the clinical and genetic data of the icf patient	Performed the experiments	Investigation	YES
5002099	27565432	AL	2	characterized the clinical and genetic data of the icf patient	characterized the clinical and genetic data of the icf patient	Performed the experiments	Investigation	YES
5002099	27565432	EE	2	conceived the methodology and designed the website architecture|wrote the code for the website|wrote the manuscript and the documentation pages	conceived the methodology and designed the website architecture	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceptualization|Methodology|Software	YES
5002099	27565432	EE	2	conceived the methodology and designed the website architecture|wrote the code for the website|wrote the manuscript and the documentation pages	wrote the code for the website	Contributed reagents/materials/analysis tools|Wrote the paper	Software|Writing - Original Draft	YES
5002099	27565432	EE	2	conceived the methodology and designed the website architecture|wrote the code for the website|wrote the manuscript and the documentation pages	wrote the manuscript and the documentation pages	Wrote the paper	Writing - Original Draft	YES
5002099	27565432	GR	2	conceived the methodology and designed the website architecture	conceived the methodology and designed the website architecture	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceptualization|Methodology|Software	YES
5002099	27565432	NA	2	conceived the methodology and designed the website architecture	conceived the methodology and designed the website architecture	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceptualization|Methodology|Software	YES
5002099	27565432	NK	2	performed the exome sequencing analysis	performed the exome sequencing analysis	Performed the experiments	Investigation	YES
5002099	27565432	OB	2	performed the exome sequencing analysis	performed the exome sequencing analysis	Performed the experiments	Investigation	YES
5002099	27565432	OS	2	wrote the code for the website	wrote the code for the website	Contributed reagents/materials/analysis tools|Wrote the paper	Software|Writing - Original Draft	YES
5002099	27565432	RS	2	characterized the clinical and genetic data of the icf patient	characterized the clinical and genetic data of the icf patient	Performed the experiments	Investigation	YES
5002099	27565432	VK	2	wrote the code for the website	wrote the code for the website	Contributed reagents/materials/analysis tools|Wrote the paper	Software|Writing - Original Draft	YES
5435751	28572812	All authors	2	approved this mini-review for the publication	approved this mini-review for the publication	-	-	NO
6359407	30577686	A.U.	2	conceptualized the work and organized it within their groups|are the leading scientists of the megagrant from the government of the russian federation, which allowed the experiments|participated in all discussions and corrected the manuscript at each stage of its preparation|prepared the manuscript	conceptualized the work and organized it within their groups	Conceived and designed the experiments	Conceptualization	YES
6359407	30577686	A.U.	2	conceptualized the work and organized it within their groups|are the leading scientists of the megagrant from the government of the russian federation, which allowed the experiments|participated in all discussions and corrected the manuscript at each stage of its preparation|prepared the manuscript	are the leading scientists of the megagrant from the government of the russian federation, which allowed the experiments	-	-	NO
6359407	30577686	A.U.	2	conceptualized the work and organized it within their groups|are the leading scientists of the megagrant from the government of the russian federation, which allowed the experiments|participated in all discussions and corrected the manuscript at each stage of its preparation|prepared the manuscript	participated in all discussions and corrected the manuscript at each stage of its preparation	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6359407	30577686	A.U.	2	conceptualized the work and organized it within their groups|are the leading scientists of the megagrant from the government of the russian federation, which allowed the experiments|participated in all discussions and corrected the manuscript at each stage of its preparation|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
6359407	30577686	Dmitry Polyakov	2	performed the in vitro phagocytosis evaluation and confocal microscopy measurements	performed the in vitro phagocytosis evaluation and confocal microscopy measurements	Performed the experiments	Investigation	YES
6359407	30577686	IgG	2	attachment to the particle surface|separation and purification	attachment to the particle surface	Performed the experiments	Investigation	YES
6359407	30577686	IgG	2	attachment to the particle surface|separation and purification	separation and purification	Performed the experiments	Investigation	YES
6359407	30577686	L.C.	2	conceptualized the work and organized it within their groups|planned the animal experiments and controlled their processing|participated in euthanized mice dissection and analysis of pathomorphological data|prepared the manuscript	conceptualized the work and organized it within their groups	Conceived and designed the experiments	Conceptualization	YES
6359407	30577686	L.C.	2	conceptualized the work and organized it within their groups|planned the animal experiments and controlled their processing|participated in euthanized mice dissection and analysis of pathomorphological data|prepared the manuscript	planned the animal experiments and controlled their processing	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
6359407	30577686	L.C.	2	conceptualized the work and organized it within their groups|planned the animal experiments and controlled their processing|participated in euthanized mice dissection and analysis of pathomorphological data|prepared the manuscript	participated in euthanized mice dissection and analysis of pathomorphological data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6359407	30577686	L.C.	2	conceptualized the work and organized it within their groups|planned the animal experiments and controlled their processing|participated in euthanized mice dissection and analysis of pathomorphological data|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
6359407	30577686	M.P.	2	were the main performers of all animal experiments in vivarium|also participated in the preparation of slices for analysis	were the main performers of all animal experiments in vivarium	Performed the experiments	Investigation	YES
6359407	30577686	M.P.	2	were the main performers of all animal experiments in vivarium|also participated in the preparation of slices for analysis	also participated in the preparation of slices for analysis	-	-	NO
6359407	30577686	N.Z.	2	were the main performers of all animal experiments in vivarium|also participated in the preparation of slices for analysis	were the main performers of all animal experiments in vivarium	Performed the experiments	Investigation	YES
6359407	30577686	N.Z.	2	were the main performers of all animal experiments in vivarium|also participated in the preparation of slices for analysis	also participated in the preparation of slices for analysis	-	-	NO
6359407	30577686	O.D.	2	conceptualized the work and organized it within their groups|planned the animal experiments and controlled their processing|participated in lc-ms analysis of the drug in the slices of the mice and discussion of results	conceptualized the work and organized it within their groups	Conceived and designed the experiments	Conceptualization	YES
6359407	30577686	O.D.	2	conceptualized the work and organized it within their groups|planned the animal experiments and controlled their processing|participated in lc-ms analysis of the drug in the slices of the mice and discussion of results	planned the animal experiments and controlled their processing	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
6359407	30577686	O.D.	2	conceptualized the work and organized it within their groups|planned the animal experiments and controlled their processing|participated in lc-ms analysis of the drug in the slices of the mice and discussion of results	participated in lc-ms analysis of the drug in the slices of the mice and discussion of results	Analyzed the data	Formal analysis	YES
6359407	30577686	P.Y.	2	conceptualized the work and organized it within their groups|managed this work as director of the institute and participated in discussions	conceptualized the work and organized it within their groups	Conceived and designed the experiments	Conceptualization	YES
6359407	30577686	P.Y.	2	conceptualized the work and organized it within their groups|managed this work as director of the institute and participated in discussions	managed this work as director of the institute and participated in discussions	-	-	NO
6359407	30577686	T.T.	2	conceptualized the work and organized it within their groups|are the leading scientists of the megagrant from the government of the russian federation, which allowed the experiments|participated in all discussions and corrected the manuscript at each stage of its preparation|prepared the manuscript	conceptualized the work and organized it within their groups	Conceived and designed the experiments	Conceptualization	YES
6359407	30577686	T.T.	2	conceptualized the work and organized it within their groups|are the leading scientists of the megagrant from the government of the russian federation, which allowed the experiments|participated in all discussions and corrected the manuscript at each stage of its preparation|prepared the manuscript	are the leading scientists of the megagrant from the government of the russian federation, which allowed the experiments	-	-	NO
6359407	30577686	T.T.	2	conceptualized the work and organized it within their groups|are the leading scientists of the megagrant from the government of the russian federation, which allowed the experiments|participated in all discussions and corrected the manuscript at each stage of its preparation|prepared the manuscript	participated in all discussions and corrected the manuscript at each stage of its preparation	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6359407	30577686	T.T.	2	conceptualized the work and organized it within their groups|are the leading scientists of the megagrant from the government of the russian federation, which allowed the experiments|participated in all discussions and corrected the manuscript at each stage of its preparation|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
6359407	30577686	T.V.	2	were the main performers of all animal experiments in vivarium|also participated in the preparation of slices for analysis	were the main performers of all animal experiments in vivarium	Performed the experiments	Investigation	YES
6359407	30577686	T.V.	2	were the main performers of all animal experiments in vivarium|also participated in the preparation of slices for analysis	also participated in the preparation of slices for analysis	-	-	NO
6359407	30577686	V.K.-V.	2	suggested the particles for idea implementation, prepared the drug-loaded micro- and nanoparticles, and performed the characterization of particles|prepared the manuscript	suggested the particles for idea implementation, prepared the drug-loaded micro- and nanoparticles, and performed the characterization of particles	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
6359407	30577686	V.K.-V.	2	suggested the particles for idea implementation, prepared the drug-loaded micro- and nanoparticles, and performed the characterization of particles|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
6359407	30577686	V.U.	2	performed the histological pathomorphological studies	performed the histological pathomorphological studies	Performed the experiments	Investigation	YES
6359407	30577686	V.Z.	2	performed the histological pathomorphological studies	performed the histological pathomorphological studies	Performed the experiments	Investigation	YES
3287109	22192455	BC	2	read and approved the final manuscript|participated in research and survey design, conducted the data collection, provided input in data analysis and reviewed the manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
3287109	22192455	BC	2	read and approved the final manuscript|participated in research and survey design, conducted the data collection, provided input in data analysis and reviewed the manuscript	participated in research and survey design, conducted the data collection, provided input in data analysis and reviewed the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Review & Editing	YES
3287109	22192455	DHdV	2	carried out the research and survey design, led the data analysis and drafted the manuscript	carried out the research and survey design, led the data analysis and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3287109	22192455	MM	2	read and approved the final manuscript|participated in research and survey design, conducted the data collection, provided input in data analysis and reviewed the manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
3287109	22192455	MM	2	read and approved the final manuscript|participated in research and survey design, conducted the data collection, provided input in data analysis and reviewed the manuscript	participated in research and survey design, conducted the data collection, provided input in data analysis and reviewed the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Review & Editing	YES
3287109	22192455	SG	2	conceived the study, participated in its design and coordination and helped draft the manuscript	conceived the study, participated in its design and coordination and helped draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
3287109	22192455	TD	2	read and approved the final manuscript|participated in research and survey design, conducted the data collection, provided input in data analysis and reviewed the manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
3287109	22192455	TD	2	read and approved the final manuscript|participated in research and survey design, conducted the data collection, provided input in data analysis and reviewed the manuscript	participated in research and survey design, conducted the data collection, provided input in data analysis and reviewed the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Review & Editing	YES
4398387	25874928	ADD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398387	25874928	ADD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398387	25874928	ADD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398387	25874928	DAC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398387	25874928	DAC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398387	25874928	DAC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398387	25874928	DAC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398387	25874928	DG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398387	25874928	DG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398387	25874928	DG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398387	25874928	DG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398387	25874928	DG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398387	25874928	GLC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398387	25874928	GLC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398387	25874928	GLC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398387	25874928	GLC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398387	25874928	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398387	25874928	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398387	25874928	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398387	25874928	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398387	25874928	LBN	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398387	25874928	LBN	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398387	25874928	LBN	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398387	25874928	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398387	25874928	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398387	25874928	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398387	25874928	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398387	25874928	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398387	25874928	PA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398387	25874928	PA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398387	25874928	PA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398387	25874928	PA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3292983	22289654	AB	2	commented on the study concept and analysis plan, helped interpretation of results and edited the manuscript	commented on the study concept and analysis plan, helped interpretation of results and edited the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Review & Editing	YES
3292983	22289654	AJ	2	commented on the study concept and analysis plan, helped interpretation of results and edited the manuscript	commented on the study concept and analysis plan, helped interpretation of results and edited the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Review & Editing	YES
3292983	22289654	BM	2	commented on the study concept and analysis plan, helped interpretation of results and edited the manuscript	commented on the study concept and analysis plan, helped interpretation of results and edited the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Review & Editing	YES
3292983	22289654	DM	2	commented on the study concept and analysis plan, helped interpretation of results and edited the manuscript	commented on the study concept and analysis plan, helped interpretation of results and edited the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Review & Editing	YES
3292983	22289654	EB	2	commented on the study concept and analysis plan, helped interpretation of results and edited the manuscript	commented on the study concept and analysis plan, helped interpretation of results and edited the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Review & Editing	YES
3292983	22289654	FW	2	commented on the study concept and analysis plan, helped interpretation of results and edited the manuscript	commented on the study concept and analysis plan, helped interpretation of results and edited the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Review & Editing	YES
3292983	22289654	JH	2	commented on the study concept and analysis plan, helped interpretation of results and edited the manuscript	commented on the study concept and analysis plan, helped interpretation of results and edited the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Review & Editing	YES
3292983	22289654	JI	2	commented on the study concept and analysis plan, helped interpretation of results and edited the manuscript	commented on the study concept and analysis plan, helped interpretation of results and edited the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Review & Editing	YES
3292983	22289654	JZ	2	originated the study concept and detailed the analysis plan|performed the data manipulation, statistical analysis, interpretation of results and drafted the manuscript	originated the study concept and detailed the analysis plan	Conceived and designed the experiments	Conceptualization	YES
3292983	22289654	JZ	2	originated the study concept and detailed the analysis plan|performed the data manipulation, statistical analysis, interpretation of results and drafted the manuscript	performed the data manipulation, statistical analysis, interpretation of results and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3292983	22289654	KW	2	commented on the study concept and analysis plan, helped interpretation of results and edited the manuscript	commented on the study concept and analysis plan, helped interpretation of results and edited the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Review & Editing	YES
3292983	22289654	ML	2	originated the study concept and detailed the analysis plan	originated the study concept and detailed the analysis plan	Conceived and designed the experiments	Conceptualization	YES
3292983	22289654	NM	2	commented on the study concept and analysis plan, helped interpretation of results and edited the manuscript	commented on the study concept and analysis plan, helped interpretation of results and edited the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Review & Editing	YES
5002109	27565572	AA	2	assisted in data analysis and the generation of figures	assisted in data analysis and the generation of figures	Analyzed the data	Formal analysis|Visualization	YES
5002109	27565572	CMB	2	assisted in data analysis and the generation of figures	assisted in data analysis and the generation of figures	Analyzed the data	Formal analysis|Visualization	YES
5002109	27565572	EL	2	performed pcr validations	performed pcr validations	Performed the experiments	Investigation|Validation	YES
5002109	27565572	JPP	2	contributed to experimental design and analysis	contributed to experimental design and analysis	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5002109	27565572	MB	2	contributed to experimental design, data analysis and wrote the manuscript with contributions from all the authors	contributed to experimental design, data analysis and wrote the manuscript with contributions from all the authors	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
5002109	27565572	MD	2	performed pcr validations	performed pcr validations	Performed the experiments	Investigation|Validation	YES
5002109	27565572	MPT	2	contributed to experimental design and analysis of the data, performed validation and co-immunoprecipitation experiments, and helped in writing the manuscript	contributed to experimental design and analysis of the data, performed validation and co-immunoprecipitation experiments, and helped in writing the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Validation|Writing - Original Draft	YES
5002109	27565572	MS	2	contributed to experimental design and analysis	contributed to experimental design and analysis	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5002109	27565572	MTL	2	contributed to experimental design and analysis	contributed to experimental design and analysis	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5002109	27565572	PT	2	performed informatics analyses	performed informatics analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5002109	27565572	SB	2	assisted in data analysis and the generation of figures	assisted in data analysis and the generation of figures	Analyzed the data	Formal analysis|Visualization	YES
5002109	27565572	VESA	2	assisted in data analysis and the generation of figures	assisted in data analysis and the generation of figures	Analyzed the data	Formal analysis|Visualization	YES
4398389	25875231	ABN	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398389	25875231	ABN	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398389	25875231	ABN	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398389	25875231	JACG	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398389	25875231	JACG	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398389	25875231	JPS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398389	25875231	JPS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398389	25875231	JPS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398389	25875231	JPS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5435766	28572809	All authors	PLoS52	revised, read, and approved the final manuscript	revised, read, and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5435766	28572809	DH	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5435766	28572809	GL	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5435766	28572809	JH	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5435766	28572809	JM	PLoS52	provided plant materials, the previous published data and suggestions	provided plant materials, the previous published data and suggestions	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5435766	28572809	JR	PLoS52	designed the research, analyzed the data, and wrote the manuscript	designed the research, analyzed the data, and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5435766	28572809	JZ	PLoS52	designed the research, analyzed the data, and wrote the manuscript	designed the research, analyzed the data, and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5435766	28572809	MW	PLoS52	analyzed the data|helped the genotyping and phenotyping of new hybrids	analyzed the data	Analyzed the data	Formal analysis	YES
5435766	28572809	MW	PLoS52	analyzed the data|helped the genotyping and phenotyping of new hybrids	helped the genotyping and phenotyping of new hybrids	Performed the experiments	Investigation	YES
5435766	28572809	PL	PLoS52	performed the research, analyzed the data, and wrote the manuscript	performed the research, analyzed the data, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5435766	28572809	YZ	PLoS52	performed the research, analyzed the data, and wrote the manuscript	performed the research, analyzed the data, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6359436	30658451	D.M.	CRediT	investigation|data curation|writing--original draft preparation	investigation	Performed the experiments	Investigation	YES
6359436	30658451	D.M.	CRediT	investigation|data curation|writing--original draft preparation	data curation	Analyzed the data	Data curation	YES
6359436	30658451	D.M.	CRediT	investigation|data curation|writing--original draft preparation	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6359436	30658451	E.B.	CRediT	investigation|data curation	investigation	Performed the experiments	Investigation	YES
6359436	30658451	E.B.	CRediT	investigation|data curation	data curation	Analyzed the data	Data curation	YES
6359436	30658451	F.S.	CRediT	investigation|data curation|writing--original draft preparation	investigation	Performed the experiments	Investigation	YES
6359436	30658451	F.S.	CRediT	investigation|data curation|writing--original draft preparation	data curation	Analyzed the data	Data curation	YES
6359436	30658451	F.S.	CRediT	investigation|data curation|writing--original draft preparation	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6359436	30658451	G.A.	CRediT	investigation|data curation	investigation	Performed the experiments	Investigation	YES
6359436	30658451	G.A.	CRediT	investigation|data curation	data curation	Analyzed the data	Data curation	YES
6359436	30658451	G.C.	CRediT	Conceptualization	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6359436	30658451	M.Z.	CRediT	Conceptualization	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6359436	30658451	V.D.C.	CRediT	Conceptualization|supervision|writing--review and editing|funding acquisition	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6359436	30658451	V.D.C.	CRediT	Conceptualization|supervision|writing--review and editing|funding acquisition	supervision	-	Supervision	YES
6359436	30658451	V.D.C.	CRediT	Conceptualization|supervision|writing--review and editing|funding acquisition	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6359436	30658451	V.D.C.	CRediT	Conceptualization|supervision|writing--review and editing|funding acquisition	funding acquisition	-	Funding acquisition	YES
4402183	25945328	Jianrui Li	2	contributed equally to this study	contributed equally to this study	-	-	NO
4402183	25945328	Yuankai Lin	2	contributed equally to this study	contributed equally to this study	-	-	NO
4398392	25875467	GR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398392	25875467	GR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398392	25875467	GR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398392	25875467	GR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398392	25875467	GR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398392	25875467	RP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398392	25875467	RP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398392	25875467	RP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398392	25875467	RP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398392	25875467	RP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3293013	22289641	AB	2	contributed to the data analysis, interpretation and the concept of this manuscript|wrote the manuscript and provided substantial intellectual content	contributed to the data analysis, interpretation and the concept of this manuscript	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
3293013	22289641	AB	2	contributed to the data analysis, interpretation and the concept of this manuscript|wrote the manuscript and provided substantial intellectual content	wrote the manuscript and provided substantial intellectual content	Wrote the paper	Writing - Original Draft	YES
3293013	22289641	AL	2	contributed to the design of the study|contributed to conducting the survey, data collection and management|contributed to the data analysis, interpretation and the concept of this manuscript|wrote the manuscript and provided substantial intellectual content	contributed to the design of the study	Conceived and designed the experiments	Methodology	YES
3293013	22289641	AL	2	contributed to the design of the study|contributed to conducting the survey, data collection and management|contributed to the data analysis, interpretation and the concept of this manuscript|wrote the manuscript and provided substantial intellectual content	contributed to conducting the survey, data collection and management	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
3293013	22289641	AL	2	contributed to the design of the study|contributed to conducting the survey, data collection and management|contributed to the data analysis, interpretation and the concept of this manuscript|wrote the manuscript and provided substantial intellectual content	contributed to the data analysis, interpretation and the concept of this manuscript	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
3293013	22289641	AL	2	contributed to the design of the study|contributed to conducting the survey, data collection and management|contributed to the data analysis, interpretation and the concept of this manuscript|wrote the manuscript and provided substantial intellectual content	wrote the manuscript and provided substantial intellectual content	Wrote the paper	Writing - Original Draft	YES
3293013	22289641	All the authors	2	reviewed the final manuscript	reviewed the final manuscript	Wrote the paper	Writing - Review & Editing	YES
3293013	22289641	CK	2	contributed to the data analysis, interpretation and the concept of this manuscript|wrote the manuscript and provided substantial intellectual content	contributed to the data analysis, interpretation and the concept of this manuscript	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
3293013	22289641	CK	2	contributed to the data analysis, interpretation and the concept of this manuscript|wrote the manuscript and provided substantial intellectual content	wrote the manuscript and provided substantial intellectual content	Wrote the paper	Writing - Original Draft	YES
3293013	22289641	CMW	2	wrote the manuscript and provided substantial intellectual content	wrote the manuscript and provided substantial intellectual content	Wrote the paper	Writing - Original Draft	YES
3293013	22289641	EN	2	contributed to the design of the study|contributed to conducting the survey, data collection and management|contributed to the data analysis, interpretation and the concept of this manuscript|wrote the manuscript and provided substantial intellectual content	contributed to the design of the study	Conceived and designed the experiments	Methodology	YES
3293013	22289641	EN	2	contributed to the design of the study|contributed to conducting the survey, data collection and management|contributed to the data analysis, interpretation and the concept of this manuscript|wrote the manuscript and provided substantial intellectual content	contributed to conducting the survey, data collection and management	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
3293013	22289641	EN	2	contributed to the design of the study|contributed to conducting the survey, data collection and management|contributed to the data analysis, interpretation and the concept of this manuscript|wrote the manuscript and provided substantial intellectual content	contributed to the data analysis, interpretation and the concept of this manuscript	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
3293013	22289641	EN	2	contributed to the design of the study|contributed to conducting the survey, data collection and management|contributed to the data analysis, interpretation and the concept of this manuscript|wrote the manuscript and provided substantial intellectual content	wrote the manuscript and provided substantial intellectual content	Wrote the paper	Writing - Original Draft	YES
3293013	22289641	HR	2	contributed to the design of the study|contributed to conducting the survey, data collection and management|contributed to the data analysis, interpretation and the concept of this manuscript|wrote the manuscript and provided substantial intellectual content	contributed to the design of the study	Conceived and designed the experiments	Methodology	YES
3293013	22289641	HR	2	contributed to the design of the study|contributed to conducting the survey, data collection and management|contributed to the data analysis, interpretation and the concept of this manuscript|wrote the manuscript and provided substantial intellectual content	contributed to conducting the survey, data collection and management	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
3293013	22289641	HR	2	contributed to the design of the study|contributed to conducting the survey, data collection and management|contributed to the data analysis, interpretation and the concept of this manuscript|wrote the manuscript and provided substantial intellectual content	contributed to the data analysis, interpretation and the concept of this manuscript	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
3293013	22289641	HR	2	contributed to the design of the study|contributed to conducting the survey, data collection and management|contributed to the data analysis, interpretation and the concept of this manuscript|wrote the manuscript and provided substantial intellectual content	wrote the manuscript and provided substantial intellectual content	Wrote the paper	Writing - Original Draft	YES
3293013	22289641	JDB	2	contributed to the design of the study|contributed to conducting the survey, data collection and management|contributed to the data analysis, interpretation and the concept of this manuscript|wrote the manuscript and provided substantial intellectual content	contributed to the design of the study	Conceived and designed the experiments	Methodology	YES
3293013	22289641	JDB	2	contributed to the design of the study|contributed to conducting the survey, data collection and management|contributed to the data analysis, interpretation and the concept of this manuscript|wrote the manuscript and provided substantial intellectual content	contributed to conducting the survey, data collection and management	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
3293013	22289641	JDB	2	contributed to the design of the study|contributed to conducting the survey, data collection and management|contributed to the data analysis, interpretation and the concept of this manuscript|wrote the manuscript and provided substantial intellectual content	contributed to the data analysis, interpretation and the concept of this manuscript	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
3293013	22289641	JDB	2	contributed to the design of the study|contributed to conducting the survey, data collection and management|contributed to the data analysis, interpretation and the concept of this manuscript|wrote the manuscript and provided substantial intellectual content	wrote the manuscript and provided substantial intellectual content	Wrote the paper	Writing - Original Draft	YES
3293013	22289641	JPN	2	contributed to the design of the study|contributed to conducting the survey, data collection and management|contributed to the data analysis, interpretation and the concept of this manuscript|wrote the manuscript and provided substantial intellectual content	contributed to the design of the study	Conceived and designed the experiments	Methodology	YES
3293013	22289641	JPN	2	contributed to the design of the study|contributed to conducting the survey, data collection and management|contributed to the data analysis, interpretation and the concept of this manuscript|wrote the manuscript and provided substantial intellectual content	contributed to conducting the survey, data collection and management	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
3293013	22289641	JPN	2	contributed to the design of the study|contributed to conducting the survey, data collection and management|contributed to the data analysis, interpretation and the concept of this manuscript|wrote the manuscript and provided substantial intellectual content	contributed to the data analysis, interpretation and the concept of this manuscript	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
3293013	22289641	JPN	2	contributed to the design of the study|contributed to conducting the survey, data collection and management|contributed to the data analysis, interpretation and the concept of this manuscript|wrote the manuscript and provided substantial intellectual content	wrote the manuscript and provided substantial intellectual content	Wrote the paper	Writing - Original Draft	YES
3293013	22289641	LT	2	contributed to the design of the study|contributed to conducting the survey, data collection and management|contributed to the data analysis, interpretation and the concept of this manuscript|wrote the manuscript and provided substantial intellectual content	contributed to the design of the study	Conceived and designed the experiments	Methodology	YES
3293013	22289641	LT	2	contributed to the design of the study|contributed to conducting the survey, data collection and management|contributed to the data analysis, interpretation and the concept of this manuscript|wrote the manuscript and provided substantial intellectual content	contributed to conducting the survey, data collection and management	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
3293013	22289641	LT	2	contributed to the design of the study|contributed to conducting the survey, data collection and management|contributed to the data analysis, interpretation and the concept of this manuscript|wrote the manuscript and provided substantial intellectual content	contributed to the data analysis, interpretation and the concept of this manuscript	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
3293013	22289641	LT	2	contributed to the design of the study|contributed to conducting the survey, data collection and management|contributed to the data analysis, interpretation and the concept of this manuscript|wrote the manuscript and provided substantial intellectual content	wrote the manuscript and provided substantial intellectual content	Wrote the paper	Writing - Original Draft	YES
3293013	22289641	NS	2	contributed to the design of the study|contributed to conducting the survey, data collection and management|contributed to the data analysis, interpretation and the concept of this manuscript|wrote the manuscript and provided substantial intellectual content	contributed to the design of the study	Conceived and designed the experiments	Methodology	YES
3293013	22289641	NS	2	contributed to the design of the study|contributed to conducting the survey, data collection and management|contributed to the data analysis, interpretation and the concept of this manuscript|wrote the manuscript and provided substantial intellectual content	contributed to conducting the survey, data collection and management	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
3293013	22289641	NS	2	contributed to the design of the study|contributed to conducting the survey, data collection and management|contributed to the data analysis, interpretation and the concept of this manuscript|wrote the manuscript and provided substantial intellectual content	contributed to the data analysis, interpretation and the concept of this manuscript	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
3293013	22289641	NS	2	contributed to the design of the study|contributed to conducting the survey, data collection and management|contributed to the data analysis, interpretation and the concept of this manuscript|wrote the manuscript and provided substantial intellectual content	wrote the manuscript and provided substantial intellectual content	Wrote the paper	Writing - Original Draft	YES
3293013	22289641	PM	2	contributed to the design of the study|contributed to conducting the survey, data collection and management|contributed to the data analysis, interpretation and the concept of this manuscript|wrote the manuscript and provided substantial intellectual content	contributed to the design of the study	Conceived and designed the experiments	Methodology	YES
3293013	22289641	PM	2	contributed to the design of the study|contributed to conducting the survey, data collection and management|contributed to the data analysis, interpretation and the concept of this manuscript|wrote the manuscript and provided substantial intellectual content	contributed to conducting the survey, data collection and management	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
3293013	22289641	PM	2	contributed to the design of the study|contributed to conducting the survey, data collection and management|contributed to the data analysis, interpretation and the concept of this manuscript|wrote the manuscript and provided substantial intellectual content	contributed to the data analysis, interpretation and the concept of this manuscript	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
3293013	22289641	PM	2	contributed to the design of the study|contributed to conducting the survey, data collection and management|contributed to the data analysis, interpretation and the concept of this manuscript|wrote the manuscript and provided substantial intellectual content	wrote the manuscript and provided substantial intellectual content	Wrote the paper	Writing - Original Draft	YES
3293013	22289641	SN	2	contributed to the design of the study|contributed to the data analysis, interpretation and the concept of this manuscript|wrote the manuscript and provided substantial intellectual content	contributed to the design of the study	Conceived and designed the experiments	Methodology	YES
3293013	22289641	SN	2	contributed to the design of the study|contributed to the data analysis, interpretation and the concept of this manuscript|wrote the manuscript and provided substantial intellectual content	contributed to the data analysis, interpretation and the concept of this manuscript	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
3293013	22289641	SN	2	contributed to the design of the study|contributed to the data analysis, interpretation and the concept of this manuscript|wrote the manuscript and provided substantial intellectual content	wrote the manuscript and provided substantial intellectual content	Wrote the paper	Writing - Original Draft	YES
3293013	22289641	VM	2	contributed to the design of the study|contributed to conducting the survey, data collection and management|contributed to the data analysis, interpretation and the concept of this manuscript|wrote the manuscript and provided substantial intellectual content	contributed to the design of the study	Conceived and designed the experiments	Methodology	YES
3293013	22289641	VM	2	contributed to the design of the study|contributed to conducting the survey, data collection and management|contributed to the data analysis, interpretation and the concept of this manuscript|wrote the manuscript and provided substantial intellectual content	contributed to conducting the survey, data collection and management	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
3293013	22289641	VM	2	contributed to the design of the study|contributed to conducting the survey, data collection and management|contributed to the data analysis, interpretation and the concept of this manuscript|wrote the manuscript and provided substantial intellectual content	contributed to the data analysis, interpretation and the concept of this manuscript	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
3293013	22289641	VM	2	contributed to the design of the study|contributed to conducting the survey, data collection and management|contributed to the data analysis, interpretation and the concept of this manuscript|wrote the manuscript and provided substantial intellectual content	wrote the manuscript and provided substantial intellectual content	Wrote the paper	Writing - Original Draft	YES
5002119	27566279	A.Ca	2	performed gdna extractions	performed gdna extractions	Performed the experiments	Investigation	YES
5002119	27566279	A.Cl	2	also contributed analysis|wrote the main text	also contributed analysis	-	-	NO
5002119	27566279	A.Cl	2	also contributed analysis|wrote the main text	wrote the main text	Wrote the paper	Writing - Original Draft	YES
5002119	27566279	A.Cl.and	2	designed the experiment	designed the experiment	Conceived and designed the experiments	Methodology	YES
5002119	27566279	A.M.	2	did the genotyping using the openarray technology	did the genotyping using the openarray technology	Performed the experiments	Investigation	YES
5002119	27566279	A.Sa	2	designed the experiment	designed the experiment	Conceived and designed the experiments	Methodology	YES
5002119	27566279	AR	2	exonic regions	exonic regions	-	-	NO
5002119	27566279	All authors	2	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5002119	27566279	M.F.	2	generated the f 2 animals and obtained the phenotypic data	generated the f 2 animals and obtained the phenotypic data	Performed the experiments	Investigation	YES
5002119	27566279	S.B.	2	contributed the sequencing steps from wetlab library prep to all the bioinformatic analysis until variant calling	contributed the sequencing steps from wetlab library prep to all the bioinformatic analysis until variant calling	Performed the experiments|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5002119	27566279	S.C.	2	generated the f 2 animals and obtained the phenotypic data	generated the f 2 animals and obtained the phenotypic data	Performed the experiments	Investigation	YES
5002119	27566279	S.D.	2	contributed the sequencing steps from wetlab library prep to all the bioinformatic analysis until variant calling	contributed the sequencing steps from wetlab library prep to all the bioinformatic analysis until variant calling	Performed the experiments|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5002119	27566279	TASR	2	exonic regions	exonic regions	-	-	NO
5435767	28572810	DW	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5435767	28572810	PJ	2	revised and checked the manuscript	revised and checked the manuscript	Wrote the paper	Writing - Review & Editing	YES
5435767	28572810	SL	2	conceived the manuscript|wrote the manuscript	conceived the manuscript	Conceived and designed the experiments	Conceptualization	YES
5435767	28572810	SL	2	conceived the manuscript|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5435767	28572810	YL	2	conceived the manuscript|revised and checked the manuscript	conceived the manuscript	Conceived and designed the experiments	Conceptualization	YES
5435767	28572810	YL	2	conceived the manuscript|revised and checked the manuscript	revised and checked the manuscript	Wrote the paper	Writing - Review & Editing	YES
6359449	30669485	A.B.	CRediT	Methodology|Software	Methodology	Performed the experiments	Methodology	YES
6359449	30669485	A.B.	CRediT	Methodology|Software	Software	Contributed reagents/materials/analysis tools	Software	YES
6359449	30669485	A.K.V.	CRediT	Methodology|Software|Funding acquisition	Methodology	Performed the experiments	Methodology	YES
6359449	30669485	A.K.V.	CRediT	Methodology|Software|Funding acquisition	Software	Contributed reagents/materials/analysis tools	Software	YES
6359449	30669485	A.K.V.	CRediT	Methodology|Software|Funding acquisition	Funding acquisition	-	Funding acquisition	YES
6359449	30669485	F.Y.	CRediT	Methodology|Data curation	Methodology	Performed the experiments	Methodology	YES
6359449	30669485	F.Y.	CRediT	Methodology|Data curation	Data curation	Analyzed the data	Data curation	YES
6359449	30669485	H.I.	CRediT	Methodology|Data curation	Methodology	Performed the experiments	Methodology	YES
6359449	30669485	H.I.	CRediT	Methodology|Data curation	Data curation	Analyzed the data	Data curation	YES
6359449	30669485	K.N.	CRediT	Conceptualization|Methodology|Validation|Investigation|Data curation|Writing--original draft preparation	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6359449	30669485	K.N.	CRediT	Conceptualization|Methodology|Validation|Investigation|Data curation|Writing--original draft preparation	Methodology	Performed the experiments	Methodology	YES
6359449	30669485	K.N.	CRediT	Conceptualization|Methodology|Validation|Investigation|Data curation|Writing--original draft preparation	Validation	Performed the experiments	Validation	YES
6359449	30669485	K.N.	CRediT	Conceptualization|Methodology|Validation|Investigation|Data curation|Writing--original draft preparation	Investigation	Performed the experiments	Investigation	YES
6359449	30669485	K.N.	CRediT	Conceptualization|Methodology|Validation|Investigation|Data curation|Writing--original draft preparation	Data curation	Analyzed the data	Data curation	YES
6359449	30669485	K.N.	CRediT	Conceptualization|Methodology|Validation|Investigation|Data curation|Writing--original draft preparation	Writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6359449	30669485	N.C.	CRediT	Methodology|Software	Methodology	Performed the experiments	Methodology	YES
6359449	30669485	N.C.	CRediT	Methodology|Software	Software	Contributed reagents/materials/analysis tools	Software	YES
6359449	30669485	N.K.	CRediT	Resources|Writing--review & editing|Supervision|Project administration|Funding acquisition	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6359449	30669485	N.K.	CRediT	Resources|Writing--review & editing|Supervision|Project administration|Funding acquisition	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6359449	30669485	N.K.	CRediT	Resources|Writing--review & editing|Supervision|Project administration|Funding acquisition	Supervision	-	Supervision	YES
6359449	30669485	N.K.	CRediT	Resources|Writing--review & editing|Supervision|Project administration|Funding acquisition	Project administration	-	Project administration	YES
6359449	30669485	N.K.	CRediT	Resources|Writing--review & editing|Supervision|Project administration|Funding acquisition	Funding acquisition	-	Funding acquisition	YES
6359449	30669485	R.T.	CRediT	Resources|Writing--review & editing|Supervision|Project administration|Funding acquisition	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6359449	30669485	R.T.	CRediT	Resources|Writing--review & editing|Supervision|Project administration|Funding acquisition	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6359449	30669485	R.T.	CRediT	Resources|Writing--review & editing|Supervision|Project administration|Funding acquisition	Supervision	-	Supervision	YES
6359449	30669485	R.T.	CRediT	Resources|Writing--review & editing|Supervision|Project administration|Funding acquisition	Project administration	-	Project administration	YES
6359449	30669485	R.T.	CRediT	Resources|Writing--review & editing|Supervision|Project administration|Funding acquisition	Funding acquisition	-	Funding acquisition	YES
6359449	30669485	S.S.	CRediT	Data curation	Data curation	Analyzed the data	Data curation	YES
6359449	30669485	T.K.	CRediT	Software	Software	Contributed reagents/materials/analysis tools	Software	YES
6359449	30669485	T.M.	CRediT	Methodology	Methodology	Performed the experiments	Methodology	YES
6359449	30669485	Y.T.	CRediT	Conceptualization|Methodology|Investigation|Data curation	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6359449	30669485	Y.T.	CRediT	Conceptualization|Methodology|Investigation|Data curation	Methodology	Performed the experiments	Methodology	YES
6359449	30669485	Y.T.	CRediT	Conceptualization|Methodology|Investigation|Data curation	Investigation	Performed the experiments	Investigation	YES
6359449	30669485	Y.T.	CRediT	Conceptualization|Methodology|Investigation|Data curation	Data curation	Analyzed the data	Data curation	YES
4398395	25874868	AP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398395	25874868	AP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398395	25874868	AP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398395	25874868	AP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398395	25874868	AW	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398395	25874868	AW	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398395	25874868	AW	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398395	25874868	CRB	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398395	25874868	CRB	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398395	25874868	DS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398395	25874868	DS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398395	25874868	GB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398395	25874868	GB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398395	25874868	GB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398395	25874868	GB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3297518	22340703	AK	2	was the analyst for the study	was the analyst for the study	-	-	NO
3297518	22340703	AS	2	are practicing physicians in kenya who developed the express care programme and contributed significantly to the generation of hypotheses and interpretation of results for the manuscript	are practicing physicians in kenya who developed the express care programme and contributed significantly to the generation of hypotheses and interpretation of results for the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Software|Writing - Original Draft	YES
3297518	22340703	ES	2	was the data manager responsible for providing and overseeing the data	was the data manager responsible for providing and overseeing the data	Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Project administration|Resources|Supervision	YES
3297518	22340703	JH	2	is the biostatistician on record for this analysis and provided significant input and technical assistance in the methodological approaches used	is the biostatistician on record for this analysis and provided significant input and technical assistance in the methodological approaches used	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
3297518	22340703	JM	2	are practicing physicians in kenya who developed the express care programme and contributed significantly to the generation of hypotheses and interpretation of results for the manuscript	are practicing physicians in kenya who developed the express care programme and contributed significantly to the generation of hypotheses and interpretation of results for the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Software|Writing - Original Draft	YES
3297518	22340703	JS	2	are practicing physicians in kenya who developed the express care programme and contributed significantly to the generation of hypotheses and interpretation of results for the manuscript	are practicing physicians in kenya who developed the express care programme and contributed significantly to the generation of hypotheses and interpretation of results for the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Software|Writing - Original Draft	YES
3297518	22340703	KWK	2	critically reviewed the manuscript for issues of design and interpretation	critically reviewed the manuscript for issues of design and interpretation	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
3297518	22340703	PB	2	was primarily responsible for the writing of the manuscript	was primarily responsible for the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
3297518	22340703	RK	2	are practicing physicians in kenya who developed the express care programme and contributed significantly to the generation of hypotheses and interpretation of results for the manuscript	are practicing physicians in kenya who developed the express care programme and contributed significantly to the generation of hypotheses and interpretation of results for the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Software|Writing - Original Draft	YES
3297518	22340703	SK	2	are practicing physicians in kenya who developed the express care programme and contributed significantly to the generation of hypotheses and interpretation of results for the manuscript	are practicing physicians in kenya who developed the express care programme and contributed significantly to the generation of hypotheses and interpretation of results for the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Software|Writing - Original Draft	YES
5435809	28572811	AM	2	conceptualized the research and designed the study|conducted the experiments and collected the data|analyzed the data with the|wrote the first version of the manuscript	conceptualized the research and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5435809	28572811	AM	2	conceptualized the research and designed the study|conducted the experiments and collected the data|analyzed the data with the|wrote the first version of the manuscript	conducted the experiments and collected the data	Performed the experiments	Investigation	YES
5435809	28572811	AM	2	conceptualized the research and designed the study|conducted the experiments and collected the data|analyzed the data with the|wrote the first version of the manuscript	analyzed the data with the	Analyzed the data	Formal analysis	YES
5435809	28572811	AM	2	conceptualized the research and designed the study|conducted the experiments and collected the data|analyzed the data with the|wrote the first version of the manuscript	wrote the first version of the manuscript	Wrote the paper	Writing - Original Draft	YES
5435809	28572811	AP	2	conceptualized the research and designed the study	conceptualized the research and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5435809	28572811	All authors	2	contributed substantially to revisions	contributed substantially to revisions	Wrote the paper	Writing - Review & Editing	YES
5435809	28572811	DW	2	conceptualized the research and designed the study|conducted the experiments and collected the data|assisted with the analyzed the data with the	conceptualized the research and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5435809	28572811	DW	2	conceptualized the research and designed the study|conducted the experiments and collected the data|assisted with the analyzed the data with the	conducted the experiments and collected the data	Performed the experiments	Investigation	YES
5435809	28572811	DW	2	conceptualized the research and designed the study|conducted the experiments and collected the data|assisted with the analyzed the data with the	assisted with the analyzed the data with the	Analyzed the data	Formal analysis	YES
5435809	28572811	JS	2	conceptualized the research and designed the study|wrote the first version of the manuscript	conceptualized the research and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5435809	28572811	JS	2	conceptualized the research and designed the study|wrote the first version of the manuscript	wrote the first version of the manuscript	Wrote the paper	Writing - Original Draft	YES
5435809	28572811	LM	2	conceptualized the research and designed the study|conducted the experiments and collected the data|assisted with the analyzed the data with the	conceptualized the research and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5435809	28572811	LM	2	conceptualized the research and designed the study|conducted the experiments and collected the data|assisted with the analyzed the data with the	conducted the experiments and collected the data	Performed the experiments	Investigation	YES
5435809	28572811	LM	2	conceptualized the research and designed the study|conducted the experiments and collected the data|assisted with the analyzed the data with the	assisted with the analyzed the data with the	Analyzed the data	Formal analysis	YES
5435809	28572811	PE	2	assisted with the analyzed the data with the	assisted with the analyzed the data with the	Analyzed the data	Formal analysis	YES
5435809	28572811	RG	2	conceptualized the research and designed the study	conceptualized the research and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398396	25875606	AFW	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4398396	25875606	AFW	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398396	25875606	ANA	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398396	25875606	ANA	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398396	25875606	ANA	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398396	25875606	ANA	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398396	25875606	EWT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398396	25875606	EWT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398396	25875606	EWT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398396	25875606	EWT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398396	25875606	EWT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398396	25875606	HJB	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398396	25875606	HJB	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4398396	25875606	HJB	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398396	25875606	JCD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398396	25875606	JCD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398396	25875606	JCD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398396	25875606	JCD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398396	25875606	JCD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398396	25875606	KCR	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398396	25875606	KCR	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4398396	25875606	KCR	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398396	25875606	MR	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398396	25875606	MR	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398396	25875606	MWO	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398396	25875606	MWO	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4398396	25875606	MWO	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398396	25875606	PRS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4398396	25875606	PRS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398396	25875606	SGG	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4398396	25875606	SGG	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
3298508	22281097	AG	2	conducted statistical analyses of study data	conducted statistical analyses of study data	Analyzed the data	Formal analysis	YES
3298508	22281097	AK	2	participated in study design, enrolled study subjects and collected clinical samples for analysis	participated in study design, enrolled study subjects and collected clinical samples for analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
3298508	22281097	All authors	2	reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
3298508	22281097	LAN	2	led and performed the standard and optimized primer data analysis	led and performed the standard and optimized primer data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3298508	22281097	QA	2	conducted analyses of clinical samples and led manuscript preparation	conducted analyses of clinical samples and led manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3298508	22281097	RT	2	conceived of the study, and participated in its design and in data interpretation	conceived of the study, and participated in its design and in data interpretation	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
3298508	22281097	RW	2	participated in study design, enrolled study subjects and collected clinical samples for analysis	participated in study design, enrolled study subjects and collected clinical samples for analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
3298508	22281097	SBF	2	participated in study design, enrolled study subjects and collected clinical samples for analysis	participated in study design, enrolled study subjects and collected clinical samples for analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
3298508	22281097	SE	2	participated in data interpretation	participated in data interpretation	Analyzed the data	Formal analysis	YES
3298508	22281097	SP	2	participated in data interpretation	participated in data interpretation	Analyzed the data	Formal analysis	YES
6359455	30621192	All authors	2	contributed to the writing of the manuscript and thoroughly reviewed the article including a joint approval of the final manuscript version	contributed to the writing of the manuscript and thoroughly reviewed the article including a joint approval of the final manuscript version	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6359455	30621192	C.P.	2	prepared the thermodynamic part of the work|conceived the study design and reviewed the results	prepared the thermodynamic part of the work	-	-	NO
6359455	30621192	C.P.	2	prepared the thermodynamic part of the work|conceived the study design and reviewed the results	conceived the study design and reviewed the results	Conceived and designed the experiments	Conceptualization|Methodology	YES
6359455	30621192	M.K.	2	conceived the study design and reviewed the results	conceived the study design and reviewed the results	Conceived and designed the experiments	Conceptualization|Methodology	YES
4402190	25945329	Guan Liu	2	contributed equally to this study	contributed equally to this study	-	-	NO
4402190	25945329	Hongfei Duan	2	contributed equally to this study	contributed equally to this study	-	-	NO
5002175	27565736	JHH	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5002175	27565736	JHH	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5002175	27565736	JHH	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5002175	27565736	JHH	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5002175	27565736	JJ	PLoS52	performed the experiments|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5002175	27565736	JJ	PLoS52	performed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5002175	27565736	KKH	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5002175	27565736	QQ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5002175	27565736	YD	PLoS52	conceived and designed the experiments|supervised the progress of the project|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5002175	27565736	YD	PLoS52	conceived and designed the experiments|supervised the progress of the project|wrote the paper	supervised the progress of the project	-	Supervision	YES
5002175	27565736	YD	PLoS52	conceived and designed the experiments|supervised the progress of the project|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5435811	28572814	CO	PLoS52	conducted experiments|analyzed data and interpreted the results|mounted images|wrote the manuscript and all the authors reviewed it and approved the final version	conducted experiments	Performed the experiments	Investigation	YES
5435811	28572814	CO	PLoS52	conducted experiments|analyzed data and interpreted the results|mounted images|wrote the manuscript and all the authors reviewed it and approved the final version	analyzed data and interpreted the results	Analyzed the data	Formal analysis	YES
5435811	28572814	CO	PLoS52	conducted experiments|analyzed data and interpreted the results|mounted images|wrote the manuscript and all the authors reviewed it and approved the final version	mounted images	Analyzed the data	Visualization	YES
5435811	28572814	CO	PLoS52	conducted experiments|analyzed data and interpreted the results|mounted images|wrote the manuscript and all the authors reviewed it and approved the final version	wrote the manuscript and all the authors reviewed it and approved the final version	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5435811	28572814	LM	PLoS52	conceived and designed the experiments|conducted experiments|analyzed data and interpreted the results|contributed materials, equipment and analysis tools|wrote the manuscript and all the authors reviewed it and approved the final version	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5435811	28572814	LM	PLoS52	conceived and designed the experiments|conducted experiments|analyzed data and interpreted the results|contributed materials, equipment and analysis tools|wrote the manuscript and all the authors reviewed it and approved the final version	conducted experiments	Performed the experiments	Investigation	YES
5435811	28572814	LM	PLoS52	conceived and designed the experiments|conducted experiments|analyzed data and interpreted the results|contributed materials, equipment and analysis tools|wrote the manuscript and all the authors reviewed it and approved the final version	analyzed data and interpreted the results	Analyzed the data	Formal analysis	YES
5435811	28572814	LM	PLoS52	conceived and designed the experiments|conducted experiments|analyzed data and interpreted the results|contributed materials, equipment and analysis tools|wrote the manuscript and all the authors reviewed it and approved the final version	contributed materials, equipment and analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5435811	28572814	LM	PLoS52	conceived and designed the experiments|conducted experiments|analyzed data and interpreted the results|contributed materials, equipment and analysis tools|wrote the manuscript and all the authors reviewed it and approved the final version	wrote the manuscript and all the authors reviewed it and approved the final version	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5435811	28572814	MB	PLoS52	conceived and designed the experiments|contributed materials, equipment and analysis tools	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5435811	28572814	MB	PLoS52	conceived and designed the experiments|contributed materials, equipment and analysis tools	contributed materials, equipment and analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5435811	28572814	MP	PLoS52	conceived and designed the experiments|conducted experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5435811	28572814	MP	PLoS52	conceived and designed the experiments|conducted experiments	conducted experiments	Performed the experiments	Investigation	YES
3298805	22353553	AOO	2	oversaw data collection and conducted statistical analysis	oversaw data collection and conducted statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Supervision	YES
3298805	22353553	CCB	2	provided statistical analysis consultation	provided statistical analysis consultation	Analyzed the data	Formal analysis	YES
3298805	22353553	CRC	2	conceived the programme and the study and helped draft and review the manuscript	conceived the programme and the study and helped draft and review the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
3298805	22353553	CWM	2	helped draft and review the manuscript	helped draft and review the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3298805	22353553	EAB	2	participated in the programme and evaluation design and helped draft the manuscript	participated in the programme and evaluation design and helped draft the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
3298805	22353553	HCM	2	provided a technical review of the draft manuscript	provided a technical review of the draft manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3298805	22353553	JAP	2	participated in the programme and evaluation design and provided technical expertise on manuscript review, coordination and editing	participated in the programme and evaluation design and provided technical expertise on manuscript review, coordination and editing	Conceived and designed the experiments|Wrote the paper	Project administration|Writing - Review & Editing	YES
3298805	22353553	JLK	2	participated in the evaluation design and took the lead in drafting the manuscript	participated in the evaluation design and took the lead in drafting the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
3298805	22353553	LN	2	helped draft and review the manuscript	helped draft and review the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3298805	22353553	PO	2	provided programme technical expertise	provided programme technical expertise	-	-	NO
3298805	22353553	RM	2	helped draft and edit the manuscript	helped draft and edit the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3298805	22353553	SBS	2	provided technical review of the evaluation design and data analysis	provided technical review of the evaluation design and data analysis	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
4398400	25875592	BZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398400	25875592	JQ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398400	25875592	JQ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398400	25875592	JQ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398400	25875592	JQ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398400	25875592	JQ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398400	25875592	LW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398400	25875592	PX	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398400	25875592	QY	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4398400	25875592	XW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398400	25875592	XZ	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
6359467	30669281	Albert Mihranyan	CRediT	Conceptualization|Funding acquisition|Investigation|Methodology|Project administration|Resources|Supervision|Writing--original draft|Writing--review & editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6359467	30669281	Albert Mihranyan	CRediT	Conceptualization|Funding acquisition|Investigation|Methodology|Project administration|Resources|Supervision|Writing--original draft|Writing--review & editing	Funding acquisition	-	Funding acquisition	YES
6359467	30669281	Albert Mihranyan	CRediT	Conceptualization|Funding acquisition|Investigation|Methodology|Project administration|Resources|Supervision|Writing--original draft|Writing--review & editing	Investigation	Performed the experiments	Investigation	YES
6359467	30669281	Albert Mihranyan	CRediT	Conceptualization|Funding acquisition|Investigation|Methodology|Project administration|Resources|Supervision|Writing--original draft|Writing--review & editing	Methodology	Performed the experiments	Methodology	YES
6359467	30669281	Albert Mihranyan	CRediT	Conceptualization|Funding acquisition|Investigation|Methodology|Project administration|Resources|Supervision|Writing--original draft|Writing--review & editing	Project administration	-	Project administration	YES
6359467	30669281	Albert Mihranyan	CRediT	Conceptualization|Funding acquisition|Investigation|Methodology|Project administration|Resources|Supervision|Writing--original draft|Writing--review & editing	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6359467	30669281	Albert Mihranyan	CRediT	Conceptualization|Funding acquisition|Investigation|Methodology|Project administration|Resources|Supervision|Writing--original draft|Writing--review & editing	Supervision	-	Supervision	YES
6359467	30669281	Albert Mihranyan	CRediT	Conceptualization|Funding acquisition|Investigation|Methodology|Project administration|Resources|Supervision|Writing--original draft|Writing--review & editing	Writing--original draft	Wrote the paper	Writing - Original Draft	YES
6359467	30669281	Albert Mihranyan	CRediT	Conceptualization|Funding acquisition|Investigation|Methodology|Project administration|Resources|Supervision|Writing--original draft|Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6359467	30669281	Athanasios Mantas	CRediT	Data curation|Formal analysis|Investigation|Writing--original draft	Data curation	Analyzed the data	Data curation	YES
6359467	30669281	Athanasios Mantas	CRediT	Data curation|Formal analysis|Investigation|Writing--original draft	Formal analysis	Analyzed the data	Formal analysis	YES
6359467	30669281	Athanasios Mantas	CRediT	Data curation|Formal analysis|Investigation|Writing--original draft	Investigation	Performed the experiments	Investigation	YES
6359467	30669281	Athanasios Mantas	CRediT	Data curation|Formal analysis|Investigation|Writing--original draft	Writing--original draft	Wrote the paper	Writing - Original Draft	YES
5002191	27567672	All authors	2	participated in discussions and read and approved the final manuscript	participated in discussions and read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5002191	27567672	EM	2	co-developed the project idea, designed and performed the analyses, interpreted the biological significance of the results, and wrote the manuscript|also coordinated the study	co-developed the project idea, designed and performed the analyses, interpreted the biological significance of the results, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5002191	27567672	EM	2	co-developed the project idea, designed and performed the analyses, interpreted the biological significance of the results, and wrote the manuscript|also coordinated the study	also coordinated the study	-	Project administration	YES
5002191	27567672	MLT	2	assisted in the biological interpretation of the results	assisted in the biological interpretation of the results	Analyzed the data	Formal analysis	YES
5002191	27567672	MP	2	co-developed the project idea, designed and performed the analyses, interpreted the biological significance of the results, and wrote the manuscript	co-developed the project idea, designed and performed the analyses, interpreted the biological significance of the results, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5002191	27567672	PO	2	co-developed the project idea, designed and performed the analyses, interpreted the biological significance of the results, and wrote the manuscript	co-developed the project idea, designed and performed the analyses, interpreted the biological significance of the results, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5781005	22974174	CM	2	assisted with the statistical analysis and reviewed final draft	assisted with the statistical analysis and reviewed final draft	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5781005	22974174	FM	2	designed the study, extracted the data, and reviewed the selected papers|drafted the manuscript and approved the final manuscript	designed the study, extracted the data, and reviewed the selected papers	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
5781005	22974174	FM	2	designed the study, extracted the data, and reviewed the selected papers|drafted the manuscript and approved the final manuscript	drafted the manuscript and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5781005	22974174	FY	2	designed the study, extracted the data, and reviewed the selected papers|drafted the manuscript and approved the final manuscript	designed the study, extracted the data, and reviewed the selected papers	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
5781005	22974174	FY	2	designed the study, extracted the data, and reviewed the selected papers|drafted the manuscript and approved the final manuscript	drafted the manuscript and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5781005	22974174	KR	2	did the statistical analyses|drafted the manuscript and approved the final manuscript	did the statistical analyses	Analyzed the data	Formal analysis	YES
5781005	22974174	KR	2	did the statistical analyses|drafted the manuscript and approved the final manuscript	drafted the manuscript and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3298806	22353579	AMcN	2	participated in the design and coordination of the study, and participated in the data analysis	participated in the design and coordination of the study, and participated in the data analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology|Project administration	YES
3298806	22353579	EG	2	participated in the design and coordination of the study, and participated in the data analysis	participated in the design and coordination of the study, and participated in the data analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology|Project administration	YES
3298806	22353579	FWW	2	participated in the design and coordination of the study, and participated in the data analysis	participated in the design and coordination of the study, and participated in the data analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology|Project administration	YES
3298806	22353579	GvR	2	participated in the design and coordination of the study, and participated in the data analysis	participated in the design and coordination of the study, and participated in the data analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology|Project administration	YES
3298806	22353579	HCG	2	participated in the data analysis, performed the statistical analysis, and drafted the manuscript	participated in the data analysis, performed the statistical analysis, and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3298806	22353579	IHdB	2	designed and coordinated the study, participated in the data analysis, and drafted the manuscript	designed and coordinated the study, participated in the data analysis, and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Project administration|Writing - Original Draft	YES
3298806	22353579	OS	2	participated in the design and coordination of the study, and helped draft the manuscript	participated in the design and coordination of the study, and helped draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft	YES
3298806	22353579	TFRdW	2	conceived of the study, participated in its design and coordination, and helped draft the manuscript	conceived of the study, participated in its design and coordination, and helped draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
5435993	28572808	DZ	2	carried out experiments and analyzed experimental results	carried out experiments and analyzed experimental results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5435993	28572808	GJ	2	designed experiments	designed experiments	Conceived and designed the experiments	Methodology	YES
5435993	28572808	HH	2	modified the manuscript	modified the manuscript	Wrote the paper	Writing - Review & Editing	YES
5435993	28572808	QC	2	carried out experiments and analyzed experimental results	carried out experiments and analyzed experimental results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5435993	28572808	QL	2	designed experiments	designed experiments	Conceived and designed the experiments	Methodology	YES
5435993	28572808	QzC	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5435993	28572808	XG	2	designed experiments|carried out experiments and analyzed experimental results|wrote the manuscript|modified the manuscript	designed experiments	Conceived and designed the experiments	Methodology	YES
5435993	28572808	XG	2	designed experiments|carried out experiments and analyzed experimental results|wrote the manuscript|modified the manuscript	carried out experiments and analyzed experimental results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5435993	28572808	XG	2	designed experiments|carried out experiments and analyzed experimental results|wrote the manuscript|modified the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5435993	28572808	XG	2	designed experiments|carried out experiments and analyzed experimental results|wrote the manuscript|modified the manuscript	modified the manuscript	Wrote the paper	Writing - Review & Editing	YES
4398401	25876036	AA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398401	25876036	AA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398401	25876036	AA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398401	25876036	AA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398401	25876036	CWR	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398401	25876036	CWR	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398401	25876036	FCD	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398401	25876036	FCD	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398401	25876036	JS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398401	25876036	JS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398401	25876036	LA	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398401	25876036	PP	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398401	25876036	PP	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398401	25876036	RC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
6359489	30598037	A.-K.R.	CRediT	Methodology|Software|Validation|Formal analysis|Investigation|Data curation|Writing-review & editing|Visualization	Methodology	Performed the experiments	Methodology	YES
6359489	30598037	A.-K.R.	CRediT	Methodology|Software|Validation|Formal analysis|Investigation|Data curation|Writing-review & editing|Visualization	Software	Contributed reagents/materials/analysis tools	Software	YES
6359489	30598037	A.-K.R.	CRediT	Methodology|Software|Validation|Formal analysis|Investigation|Data curation|Writing-review & editing|Visualization	Validation	Performed the experiments	Validation	YES
6359489	30598037	A.-K.R.	CRediT	Methodology|Software|Validation|Formal analysis|Investigation|Data curation|Writing-review & editing|Visualization	Formal analysis	Analyzed the data	Formal analysis	YES
6359489	30598037	A.-K.R.	CRediT	Methodology|Software|Validation|Formal analysis|Investigation|Data curation|Writing-review & editing|Visualization	Investigation	Performed the experiments	Investigation	YES
6359489	30598037	A.-K.R.	CRediT	Methodology|Software|Validation|Formal analysis|Investigation|Data curation|Writing-review & editing|Visualization	Data curation	Analyzed the data	Data curation	YES
6359489	30598037	A.-K.R.	CRediT	Methodology|Software|Validation|Formal analysis|Investigation|Data curation|Writing-review & editing|Visualization	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6359489	30598037	A.-K.R.	CRediT	Methodology|Software|Validation|Formal analysis|Investigation|Data curation|Writing-review & editing|Visualization	Visualization	Analyzed the data	Visualization	YES
6359489	30598037	A.U.	CRediT	Conceptualization|Methodology|Formal analysis|Resources|Writing-original draft preparation|Writing-review & editing|Visualization|Supervision|Project administration|Funding acquisition	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6359489	30598037	A.U.	CRediT	Conceptualization|Methodology|Formal analysis|Resources|Writing-original draft preparation|Writing-review & editing|Visualization|Supervision|Project administration|Funding acquisition	Methodology	Performed the experiments	Methodology	YES
6359489	30598037	A.U.	CRediT	Conceptualization|Methodology|Formal analysis|Resources|Writing-original draft preparation|Writing-review & editing|Visualization|Supervision|Project administration|Funding acquisition	Formal analysis	Analyzed the data	Formal analysis	YES
6359489	30598037	A.U.	CRediT	Conceptualization|Methodology|Formal analysis|Resources|Writing-original draft preparation|Writing-review & editing|Visualization|Supervision|Project administration|Funding acquisition	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6359489	30598037	A.U.	CRediT	Conceptualization|Methodology|Formal analysis|Resources|Writing-original draft preparation|Writing-review & editing|Visualization|Supervision|Project administration|Funding acquisition	Writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
6359489	30598037	A.U.	CRediT	Conceptualization|Methodology|Formal analysis|Resources|Writing-original draft preparation|Writing-review & editing|Visualization|Supervision|Project administration|Funding acquisition	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6359489	30598037	A.U.	CRediT	Conceptualization|Methodology|Formal analysis|Resources|Writing-original draft preparation|Writing-review & editing|Visualization|Supervision|Project administration|Funding acquisition	Visualization	Analyzed the data	Visualization	YES
6359489	30598037	A.U.	CRediT	Conceptualization|Methodology|Formal analysis|Resources|Writing-original draft preparation|Writing-review & editing|Visualization|Supervision|Project administration|Funding acquisition	Supervision	-	Supervision	YES
6359489	30598037	A.U.	CRediT	Conceptualization|Methodology|Formal analysis|Resources|Writing-original draft preparation|Writing-review & editing|Visualization|Supervision|Project administration|Funding acquisition	Project administration	-	Project administration	YES
6359489	30598037	A.U.	CRediT	Conceptualization|Methodology|Formal analysis|Resources|Writing-original draft preparation|Writing-review & editing|Visualization|Supervision|Project administration|Funding acquisition	Funding acquisition	-	Funding acquisition	YES
6359489	30598037	F.D.	CRediT	Conceptualization|Methodology|Software|Investigation|Writing-review & editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6359489	30598037	F.D.	CRediT	Conceptualization|Methodology|Software|Investigation|Writing-review & editing	Methodology	Performed the experiments	Methodology	YES
6359489	30598037	F.D.	CRediT	Conceptualization|Methodology|Software|Investigation|Writing-review & editing	Software	Contributed reagents/materials/analysis tools	Software	YES
6359489	30598037	F.D.	CRediT	Conceptualization|Methodology|Software|Investigation|Writing-review & editing	Investigation	Performed the experiments	Investigation	YES
6359489	30598037	F.D.	CRediT	Conceptualization|Methodology|Software|Investigation|Writing-review & editing	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6359489	30598037	H.K.	CRediT	Resources|Writing-review & editing|Supervision|Project administration	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6359489	30598037	H.K.	CRediT	Resources|Writing-review & editing|Supervision|Project administration	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6359489	30598037	H.K.	CRediT	Resources|Writing-review & editing|Supervision|Project administration	Supervision	-	Supervision	YES
6359489	30598037	H.K.	CRediT	Resources|Writing-review & editing|Supervision|Project administration	Project administration	-	Project administration	YES
6359489	30598037	I.K.	CRediT	Conceptualization|Methodology|Software|Formal analysis|Investigation|Writing-review & editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6359489	30598037	I.K.	CRediT	Conceptualization|Methodology|Software|Formal analysis|Investigation|Writing-review & editing	Methodology	Performed the experiments	Methodology	YES
6359489	30598037	I.K.	CRediT	Conceptualization|Methodology|Software|Formal analysis|Investigation|Writing-review & editing	Software	Contributed reagents/materials/analysis tools	Software	YES
6359489	30598037	I.K.	CRediT	Conceptualization|Methodology|Software|Formal analysis|Investigation|Writing-review & editing	Formal analysis	Analyzed the data	Formal analysis	YES
6359489	30598037	I.K.	CRediT	Conceptualization|Methodology|Software|Formal analysis|Investigation|Writing-review & editing	Investigation	Performed the experiments	Investigation	YES
6359489	30598037	I.K.	CRediT	Conceptualization|Methodology|Software|Formal analysis|Investigation|Writing-review & editing	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
3305561	22340659	ABG	2	participated in the data collection, the data analysis and the writing of the paper	participated in the data collection, the data analysis and the writing of the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3305561	22340659	EAM	2	participated in the data collection, the data analysis and the writing of the paper	participated in the data collection, the data analysis and the writing of the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3305561	22340659	MMDP	2	participated in the data collection, the data analysis and the writing of the paper|has taken the main lead in the revision of the paper	participated in the data collection, the data analysis and the writing of the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3305561	22340659	MMDP	2	participated in the data collection, the data analysis and the writing of the paper|has taken the main lead in the revision of the paper	has taken the main lead in the revision of the paper	Wrote the paper	Writing - Review & Editing	YES
5437146	28579993	All authors	PLoS52	read and approved the manuscript	read and approved the manuscript	-	-	NO
5437146	28579993	DS	PLoS52	partially revised the manuscript	partially revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5437146	28579993	GW	PLoS52	performed experiments and analyzed data	performed experiments and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5437146	28579993	LZ	PLoS52	performed experiments and analyzed data	performed experiments and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5437146	28579993	WL	PLoS52	conceived and designed the work|wrote the paper	conceived and designed the work	Conceived and designed the experiments	Conceptualization	YES
5437146	28579993	WL	PLoS52	conceived and designed the work|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5437146	28579993	YDZ	PLoS52	performed experiments and analyzed data	performed experiments and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5437146	28579993	YWZ	PLoS52	conceived and designed the work	conceived and designed the work	Conceived and designed the experiments	Conceptualization	YES
5002200	27565139	HW	2	supervised research and contributed to data analysis, discussion and writing of the manuscript	supervised research and contributed to data analysis, discussion and writing of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Supervision|Writing - Original Draft	YES
5002200	27565139	IE	2	designed and supervised research, contributed to data analysis, discussion and writing of the manuscript	designed and supervised research, contributed to data analysis, discussion and writing of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Supervision|Writing - Original Draft	YES
5002200	27565139	MH	2	processed and analyzed data, discussed data and drafted the manuscript	processed and analyzed data, discussed data and drafted the manuscript	Analyzed the data|Wrote the paper	Data curation|Formal analysis|Writing - Original Draft	YES
5002200	27565139	TAW	2	contributed to writing of the manuscript	contributed to writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
4402196	25945327	Chang-Ro Lee	2	contributed equally to this work	contributed equally to this work	-	-	NO
4402196	25945327	Jung Hun Lee	2	contributed equally to this work	contributed equally to this work	-	-	NO
4398402	25875769	FT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398402	25875769	FT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398402	25875769	FT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398402	25875769	FT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398402	25875769	GG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398402	25875769	GG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398402	25875769	GG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398402	25875769	GG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398402	25875769	JBM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4398402	25875769	JBM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398402	25875769	SA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398402	25875769	SA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398402	25875769	SA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398402	25875769	SA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398402	25875769	SA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398402	25875769	SH	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398402	25875769	SO	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398402	25875769	SO	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398402	25875769	SO	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398402	25875769	VA	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398402	25875769	XC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398402	25875769	XC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398402	25875769	XC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6359514	30621307	A.M.-I.	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
6359514	30621307	A.T.	CRediT	Writing--original draft	Writing--original draft	Wrote the paper	Writing - Original Draft	YES
6359514	30621307	F.N.-P.	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
6359514	30621307	J.R.	CRediT	Writing--original draft	Writing--original draft	Wrote the paper	Writing - Original Draft	YES
6359514	30621307	M.D.V.	CRediT	Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6359514	30621307	R.C.-L.	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
6359514	30621307	R.R.-C.	CRediT	Writing--original draft	Writing--original draft	Wrote the paper	Writing - Original Draft	YES
3306203	22360788	All authors	2	participated in the conception, design and administration of the study	participated in the conception, design and administration of the study	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
3306203	22360788	BA	2	performed statistical analyses	performed statistical analyses	Analyzed the data	Formal analysis	YES
3306203	22360788	RW	2	performed statistical analyses|wrote the initial draft of the manuscript	performed statistical analyses	Analyzed the data	Formal analysis	YES
3306203	22360788	RW	2	performed statistical analyses|wrote the initial draft of the manuscript	wrote the initial draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
5781195	23136977	MG	2	participated in the design, laboratory testing, and helped to write the manuscript	participated in the design, laboratory testing, and helped to write the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5781195	23136977	MLB	2	participated in the design, laboratory testing, and helped to write the manuscript	participated in the design, laboratory testing, and helped to write the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5781195	23136977	MRA	2	conceived of the study, participated in its design and coordination, and drafted the manuscript	conceived of the study, participated in its design and coordination, and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
5006273	27580854	BC	2	initiated the study and contributed to its design|prepared the manuscript	initiated the study and contributed to its design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5006273	27580854	BC	2	initiated the study and contributed to its design|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5006273	27580854	DH	2	initiated the study and contributed to its design|prepared the manuscript	initiated the study and contributed to its design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5006273	27580854	DH	2	initiated the study and contributed to its design|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5006273	27580854	SR	2	contributed to the design of the statistical analysis	contributed to the design of the statistical analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis	YES
5006273	27580854	SS	2	carried out the numerical data analysis	carried out the numerical data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4402467	25945347	Rumyana Dimova	2	contributed equally to this work	contributed equally to this work	-	-	NO
4402467	25945347	Tsvetalina Tankova	2	contributed equally to this work	contributed equally to this work	-	-	NO
5437152	28579998	FP	7	planning, design of experiments, and writing of the manuscript	planning, design of experiments, and writing of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5437152	28579998	HP	7	collaborated with experiments carried-out in GSE	collaborated with experiments carried-out in GSE	Performed the experiments	Investigation	YES
5437152	28579998	KA	7	performed aba determinations	performed aba determinations	Performed the experiments	Investigation	YES
5437152	28579998	RV	7	planification and revision of the manuscript and performed most of the experiments	planification and revision of the manuscript and performed most of the experiments	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5437152	28579998	XN	7	performed rt-qpcr experiments	performed rt-qpcr experiments	Performed the experiments	Investigation	YES
4398403	25875472	AWT	PLoS5	Wrote the paper|Critical revision of the manuscript for important intellectual content	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398403	25875472	AWT	PLoS5	Wrote the paper|Critical revision of the manuscript for important intellectual content	Critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4398403	25875472	GAW	PLoS5	Conceived and designed the experiments|Wrote the paper|Critical revision of the manuscript for important intellectual content	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398403	25875472	GAW	PLoS5	Conceived and designed the experiments|Wrote the paper|Critical revision of the manuscript for important intellectual content	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398403	25875472	GAW	PLoS5	Conceived and designed the experiments|Wrote the paper|Critical revision of the manuscript for important intellectual content	Critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4398403	25875472	PYB	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398403	25875472	PYB	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398403	25875472	RWM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4398403	25875472	RWM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398403	25875472	SAM	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398403	25875472	SAM	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398403	25875472	ZS	PLoS5	Wrote the paper|Critical revision of the manuscript for important intellectual content	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398403	25875472	ZS	PLoS5	Wrote the paper|Critical revision of the manuscript for important intellectual content	Critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
6359528	30609825	All authors	2	were involved in revising and final approval of the manuscript	were involved in revising and final approval of the manuscript	Wrote the paper	Writing - Review & Editing	YES
6359528	30609825	D.T.	2	were part of the project administration|conceptualized the work and obtained the funding	were part of the project administration	-	Project administration	YES
6359528	30609825	D.T.	2	were part of the project administration|conceptualized the work and obtained the funding	conceptualized the work and obtained the funding	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
6359528	30609825	L.G.d.R.	2	planned and designed the experiments and analysed the data|wrote the manuscript	planned and designed the experiments and analysed the data	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
6359528	30609825	L.G.d.R.	2	planned and designed the experiments and analysed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6359528	30609825	L.M.M.	2	helped with the methodology used in the paper	helped with the methodology used in the paper	Performed the experiments	Methodology	YES
6359528	30609825	M.S.	2	planned and designed the experiments and analysed the data	planned and designed the experiments and analysed the data	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
6359528	30609825	N.W.	2	were part of the project administration|conceptualized the work and obtained the funding	were part of the project administration	-	Project administration	YES
6359528	30609825	N.W.	2	were part of the project administration|conceptualized the work and obtained the funding	conceptualized the work and obtained the funding	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
6359528	30609825	P.M.Y.	2	were part of the project administration|conceptualized the work and obtained the funding	were part of the project administration	-	Project administration	YES
6359528	30609825	P.M.Y.	2	were part of the project administration|conceptualized the work and obtained the funding	conceptualized the work and obtained the funding	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
6359528	30609825	R.J.	2	were part of the project administration	were part of the project administration	-	Project administration	YES
6359528	30609825	W.-H.L.	2	helped with the methodology used in the paper	helped with the methodology used in the paper	Performed the experiments	Methodology	YES
3310849	22284546	All authors	2	gave their final approval of the version to be published	gave their final approval of the version to be published	-	-	NO
3310849	22284546	DKG	2	undertook project conception and design, was involved in the analysis and interpretation of data and drafted and critically revised the manuscript	undertook project conception and design, was involved in the analysis and interpretation of data and drafted and critically revised the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
3310849	22284546	MF	2	were local study coordinators and were responsible for organizing patients and collating data	were local study coordinators and were responsible for organizing patients and collating data	-	Project administration	YES
3310849	22284546	MS	2	were local study coordinators and were responsible for organizing patients and collating data	were local study coordinators and were responsible for organizing patients and collating data	-	Project administration	YES
3310849	22284546	RO	2	gave input into the conception and design of the project and critically revised the manuscript|additionally organized ethics clearance for this study	gave input into the conception and design of the project and critically revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
3310849	22284546	RO	2	gave input into the conception and design of the project and critically revised the manuscript|additionally organized ethics clearance for this study	additionally organized ethics clearance for this study	-	Project administration	YES
3310849	22284546	WDFV	2	gave input into the conception and design of the project and critically revised the manuscript	gave input into the conception and design of the project and critically revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
3310849	22284546	WSS	2	gave input into the conception and design of the project and critically revised the manuscript	gave input into the conception and design of the project and critically revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
3313880	22400977	All other authors	2	contributed equally to the manuscript by providing comments on subsequent drafts	contributed equally to the manuscript by providing comments on subsequent drafts	Wrote the paper	Writing - Original Draft	YES
3313880	22400977	SH	2	wrote the first draft of the article	wrote the first draft of the article	Wrote the paper	Writing - Original Draft	YES
4398404	25874867	ADJ	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398404	25874867	ADJ	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398404	25874867	BC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398404	25874867	BC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398404	25874867	BC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398404	25874867	BTK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398404	25874867	BTK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398404	25874867	BTK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398404	25874867	CK	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398404	25874867	CK	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398404	25874867	CW	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398404	25874867	CW	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398404	25874867	GB	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398404	25874867	GB	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398404	25874867	JJN	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398404	25874867	JJN	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398404	25874867	JJN	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398404	25874867	MS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398404	25874867	MS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398404	25874867	MS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398404	25874867	PG	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398404	25874867	PG	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398404	25874867	TO	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398404	25874867	TO	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6359546	30669292	G.L.	2	designed and supervised this research	designed and supervised this research	Conceived and designed the experiments	Methodology|Supervision	YES
6359546	30669292	G.X.	2	performed the pk study	performed the pk study	Performed the experiments	Investigation	YES
6359546	30669292	H.L.	2	performed the pk study	performed the pk study	Performed the experiments	Investigation	YES
6359546	30669292	J.H.	2	designed and supervised this research	designed and supervised this research	Conceived and designed the experiments	Methodology|Supervision	YES
6359546	30669292	L.S.	2	designed and supervised this research|contributed to the final preparation of this paper and submission	designed and supervised this research	Conceived and designed the experiments	Methodology|Supervision	YES
6359546	30669292	L.S.	2	designed and supervised this research|contributed to the final preparation of this paper and submission	contributed to the final preparation of this paper and submission	-	-	NO
6359546	30669292	Q.L.	2	performed the pk study	performed the pk study	Performed the experiments	Investigation	YES
6359546	30669292	W.L.	2	performed the pk study	performed the pk study	Performed the experiments	Investigation	YES
6359546	30669292	W.Z.	2	carried out experimental work, analyzed the data, and wrote the manuscript	carried out experimental work, analyzed the data, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5437156	28580004	AD	2	designed the experiment, assisted with data analysis, wrote and edited the manuscript	designed the experiment, assisted with data analysis, wrote and edited the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5437156	28580004	BT	2	designed the experiment, assisted with data analysis, wrote and edited the manuscript|conceived and directed the project	designed the experiment, assisted with data analysis, wrote and edited the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5437156	28580004	BT	2	designed the experiment, assisted with data analysis, wrote and edited the manuscript|conceived and directed the project	conceived and directed the project	Conceived and designed the experiments	Conceptualization|Supervision	YES
5437156	28580004	MS	2	conducted the experiments, analyzed the data and wrote the manuscript	conducted the experiments, analyzed the data and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5006276	27576376	BG	2	participated in the data collection and analyses	participated in the data collection and analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5006276	27576376	CY	2	participated in the data collection and analyses|tested the software	participated in the data collection and analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5006276	27576376	CY	2	participated in the data collection and analyses|tested the software	tested the software	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5006276	27576376	HJW	2	conceived the study|derived formulas/implemented the algorithm, wrote the software, collected data, and performed the analyses|wrote the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5006276	27576376	HJW	2	conceived the study|derived formulas/implemented the algorithm, wrote the software, collected data, and performed the analyses|wrote the manuscript	derived formulas/implemented the algorithm, wrote the software, collected data, and performed the analyses	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Software|Writing - Original Draft	YES
5006276	27576376	HJW	2	conceived the study|derived formulas/implemented the algorithm, wrote the software, collected data, and performed the analyses|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5006276	27576376	JR	2	conceived the study|participated in the data collection and analyses|wrote the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5006276	27576376	JR	2	conceived the study|participated in the data collection and analyses|wrote the manuscript	participated in the data collection and analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5006276	27576376	JR	2	conceived the study|participated in the data collection and analyses|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5006276	27576376	KK	2	participated in the data collection and analyses|tested the software	participated in the data collection and analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5006276	27576376	KK	2	participated in the data collection and analyses|tested the software	tested the software	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
3313883	22204313	BR	2	assisted with statistical analyses and manuscript writing	assisted with statistical analyses and manuscript writing	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3313883	22204313	CF	2	assisted with data interpretation and manuscript drafting	assisted with data interpretation and manuscript drafting	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3313883	22204313	DMN	2	assisted with study design and data interpretation	assisted with study design and data interpretation	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
3313883	22204313	JK	2	undertook conception and design of the study, data acquisition, analysis, interpretation and drafting of the manuscript|oversight of study conception and design, data analysis, manuscript writing and obtained grant funding	undertook conception and design of the study, data acquisition, analysis, interpretation and drafting of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
3313883	22204313	JK	2	undertook conception and design of the study, data acquisition, analysis, interpretation and drafting of the manuscript|oversight of study conception and design, data analysis, manuscript writing and obtained grant funding	oversight of study conception and design, data analysis, manuscript writing and obtained grant funding	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Funding acquisition|Methodology|Supervision|Writing - Original Draft	YES
3313883	22204313	JNK	2	assisted with study design, implementation, analysis and manuscript drafting	assisted with study design, implementation, analysis and manuscript drafting	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
3313883	22204313	RN	2	assisted with study design, data interpretation and manuscript drafting	assisted with study design, data interpretation and manuscript drafting	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4398405	25875011	AB	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398405	25875011	AK	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398405	25875011	BJ	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398405	25875011	BJ	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398405	25875011	BP	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4398405	25875011	BP	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398405	25875011	NH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398405	25875011	NH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398405	25875011	NH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398405	25875011	NH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398405	25875011	NH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5006282	27576892	GM	2	inititated the idea, supervised the studies, measured the lc-ms data and revised the manuscript	inititated the idea, supervised the studies, measured the lc-ms data and revised the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Supervision|Writing - Review & Editing	YES
3313885	22410312	All authors	2	contributed to the conception and design of the study|revised the manuscript critically for intellectual content and have approved the submitted version for publication	contributed to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3313885	22410312	All authors	2	contributed to the conception and design of the study|revised the manuscript critically for intellectual content and have approved the submitted version for publication	revised the manuscript critically for intellectual content and have approved the submitted version for publication	Wrote the paper	Writing - Review & Editing	YES
3313885	22410312	DW	2	performed the statistical analysis|interpreted the analysis and drafted the manuscript	performed the statistical analysis	Analyzed the data	Formal analysis	YES
3313885	22410312	DW	2	performed the statistical analysis|interpreted the analysis and drafted the manuscript	interpreted the analysis and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3313885	22410312	IS	2	contributed to acquisition of data	contributed to acquisition of data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
3313885	22410312	MF	2	interpreted the analysis and drafted the manuscript	interpreted the analysis and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3313885	22410312	MM	2	contributed to acquisition of data|interpreted the analysis and drafted the manuscript	contributed to acquisition of data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
3313885	22410312	MM	2	contributed to acquisition of data|interpreted the analysis and drafted the manuscript	interpreted the analysis and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3313885	22410312	TM	2	contributed to acquisition of data	contributed to acquisition of data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5437170	28579995	TP	2	conceived the experiments|ordered and attached the accessory components|wrote the manuscript	conceived the experiments	Conceived and designed the experiments	Conceptualization	YES
5437170	28579995	TP	2	conceived the experiments|ordered and attached the accessory components|wrote the manuscript	ordered and attached the accessory components	-	-	NO
5437170	28579995	TP	2	conceived the experiments|ordered and attached the accessory components|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5437170	28579995	ZN	2	conceived the experiments|wrote the manuscript	conceived the experiments	Conceived and designed the experiments	Conceptualization	YES
5437170	28579995	ZN	2	conceived the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5781198	23575174	Marnie Levine	2	contributed to pyrosequencing assay design and analysis of influenza viruses and clinical specimens	contributed to pyrosequencing assay design and analysis of influenza viruses and clinical specimens	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5781198	23575174	Rebecca J. Garten	2	contributed to analysis of sanger sequencing data	contributed to analysis of sanger sequencing data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5781198	23575174	Vasiliy P. Mishin	2	facilitated development of the second version of the jaspr curve-fitting software	facilitated development of the second version of the jaspr curve-fitting software	Contributed reagents/materials/analysis tools	Software	YES
4398406	25876004	BHJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398406	25876004	BHJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398406	25876004	BHJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398406	25876004	BHJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398406	25876004	BHJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398406	25876004	CRC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398406	25876004	CRC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398406	25876004	CRC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398406	25876004	GYS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398406	25876004	GYS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398406	25876004	GYS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398406	25876004	HY	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398406	25876004	HY	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398406	25876004	HY	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398406	25876004	JN	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398406	25876004	JN	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398406	25876004	JN	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398406	25876004	JN	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398406	25876004	KJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398406	25876004	KJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398406	25876004	KJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398406	25876004	KJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398406	25876004	KJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398406	25876004	MGK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398406	25876004	MGK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398406	25876004	MGK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398406	25876004	MGK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398406	25876004	MGK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5437204	28579997	GJ	2	designed research|performed research and analyzed data	designed research	Conceived and designed the experiments	Methodology	YES
5437204	28579997	GJ	2	designed research|performed research and analyzed data	performed research and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5437204	28579997	JA	2	performed research and analyzed data	performed research and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5437204	28579997	TF	2	designed research|performed research and analyzed data	designed research	Conceived and designed the experiments	Methodology	YES
5437204	28579997	TF	2	designed research|performed research and analyzed data	performed research and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3334674	22424402	FB-S	2	designed and co-chaired the conference satellite session on which this paper is based, and co-authored this paper	designed and co-chaired the conference satellite session on which this paper is based, and co-authored this paper	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
3334674	22424402	RJ	2	designed and co-chaired the conference satellite session on which this paper is based, and co-authored this paper	designed and co-chaired the conference satellite session on which this paper is based, and co-authored this paper	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
6359586	30669246	A.H.	CRediT	Methodology|Validation|Investigation|Writing-original draft preparation|Visualization	Methodology	Performed the experiments	Methodology	YES
6359586	30669246	A.H.	CRediT	Methodology|Validation|Investigation|Writing-original draft preparation|Visualization	Validation	Performed the experiments	Validation	YES
6359586	30669246	A.H.	CRediT	Methodology|Validation|Investigation|Writing-original draft preparation|Visualization	Investigation	Performed the experiments	Investigation	YES
6359586	30669246	A.H.	CRediT	Methodology|Validation|Investigation|Writing-original draft preparation|Visualization	Writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
6359586	30669246	A.H.	CRediT	Methodology|Validation|Investigation|Writing-original draft preparation|Visualization	Visualization	Analyzed the data	Visualization	YES
6359586	30669246	C.W.	CRediT	Methodology|Validation|Investigation|Writing-review & editing	Methodology	Performed the experiments	Methodology	YES
6359586	30669246	C.W.	CRediT	Methodology|Validation|Investigation|Writing-review & editing	Validation	Performed the experiments	Validation	YES
6359586	30669246	C.W.	CRediT	Methodology|Validation|Investigation|Writing-review & editing	Investigation	Performed the experiments	Investigation	YES
6359586	30669246	C.W.	CRediT	Methodology|Validation|Investigation|Writing-review & editing	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6359586	30669246	J.H.	CRediT	Conceptualization|Methodology|Supervision|Writing-review & editing|Funding acquisition	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6359586	30669246	J.H.	CRediT	Conceptualization|Methodology|Supervision|Writing-review & editing|Funding acquisition	Methodology	Performed the experiments	Methodology	YES
6359586	30669246	J.H.	CRediT	Conceptualization|Methodology|Supervision|Writing-review & editing|Funding acquisition	Supervision	-	Supervision	YES
6359586	30669246	J.H.	CRediT	Conceptualization|Methodology|Supervision|Writing-review & editing|Funding acquisition	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6359586	30669246	J.H.	CRediT	Conceptualization|Methodology|Supervision|Writing-review & editing|Funding acquisition	Funding acquisition	-	Funding acquisition	YES
6359586	30669246	L.d.P.	CRediT	Conceptualization|Supervision|Writing-review & editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6359586	30669246	L.d.P.	CRediT	Conceptualization|Supervision|Writing-review & editing	Supervision	-	Supervision	YES
6359586	30669246	L.d.P.	CRediT	Conceptualization|Supervision|Writing-review & editing	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6359586	30669246	M.G.	CRediT	Methodology|Investigation|Writing-review & editing|Visualization	Methodology	Performed the experiments	Methodology	YES
6359586	30669246	M.G.	CRediT	Methodology|Investigation|Writing-review & editing|Visualization	Investigation	Performed the experiments	Investigation	YES
6359586	30669246	M.G.	CRediT	Methodology|Investigation|Writing-review & editing|Visualization	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6359586	30669246	M.G.	CRediT	Methodology|Investigation|Writing-review & editing|Visualization	Visualization	Analyzed the data	Visualization	YES
4398407	25874906	AMF	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398407	25874906	CE	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398407	25874906	CM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398407	25874906	DB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398407	25874906	DB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398407	25874906	DB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398407	25874906	DB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398407	25874906	DB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398407	25874906	ES	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398407	25874906	GV	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398407	25874906	LDB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398407	25874906	LDB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398407	25874906	LDB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398407	25874906	LDB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398407	25874906	LDB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398407	25874906	PS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398407	25874906	VG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398407	25874906	VG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398407	25874906	VG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398407	25874906	VG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398407	25874906	VG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5781199	23552014	Chun-Kwok Wong	1	Concept and design	Concept and design	Conceived and designed the experiments	Conceptualization	YES
5781199	23552014	Nelson Lee	1	Concept and design|Drafting of the article	Concept and design	Conceived and designed the experiments	Conceptualization	YES
5781199	23552014	Nelson Lee	1	Concept and design|Drafting of the article	Drafting of the article	Wrote the paper	Writing - Original Draft	YES
5006322	27576563	AS	2	conceived of the experiment|managed the project	conceived of the experiment	Conceived and designed the experiments	Conceptualization	YES
5006322	27576563	AS	2	conceived of the experiment|managed the project	managed the project	-	Project administration	YES
5006322	27576563	CF	2	conducted the dog mirna body atlas experiment and collaborated with eli lilly to share the rat and dog sequencing data	conducted the dog mirna body atlas experiment and collaborated with eli lilly to share the rat and dog sequencing data	Performed the experiments	Investigation	YES
5006322	27576563	DH	2	provided guidance on which portions of organs pathologists normally investigate and detailed how the brain and other large organs were dissected	provided guidance on which portions of organs pathologists normally investigate and detailed how the brain and other large organs were dissected	Performed the experiments	Investigation|Supervision	YES
5006322	27576563	DW	2	managed the project	managed the project	-	Project administration	YES
5006322	27576563	EK	2	conducted the dog mirna body atlas experiment and collaborated with eli lilly to share the rat and dog sequencing data	conducted the dog mirna body atlas experiment and collaborated with eli lilly to share the rat and dog sequencing data	Performed the experiments	Investigation	YES
5006322	27576563	FC	2	performed independent analysis of the mirna sequencing data	performed independent analysis of the mirna sequencing data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5006322	27576563	HQ	2	contributed to experimental design, read mapping and statistical analysis of the data	contributed to experimental design, read mapping and statistical analysis of the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Methodology|Resources	YES
5006322	27576563	HW	2	contributed to experimental design, read mapping and statistical analysis of the data	contributed to experimental design, read mapping and statistical analysis of the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Methodology|Resources	YES
5006322	27576563	JC	2	contributed to experimental design, read mapping and statistical analysis of the data	contributed to experimental design, read mapping and statistical analysis of the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Methodology|Resources	YES
5006322	27576563	JL	2	performed independent analysis of the mirna sequencing data	performed independent analysis of the mirna sequencing data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5006322	27576563	MF	2	contributed to experimental design, read mapping and statistical analysis of the data	contributed to experimental design, read mapping and statistical analysis of the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Methodology|Resources	YES
5006322	27576563	PB	2	performed independent analysis of the mirna sequencing data	performed independent analysis of the mirna sequencing data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5006322	27576563	PK	2	conducted the dog mirna body atlas experiment and collaborated with eli lilly to share the rat and dog sequencing data	conducted the dog mirna body atlas experiment and collaborated with eli lilly to share the rat and dog sequencing data	Performed the experiments	Investigation	YES
5006322	27576563	SM	2	contributed to experimental design, read mapping and statistical analysis of the data	contributed to experimental design, read mapping and statistical analysis of the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Methodology|Resources	YES
3334679	22417404	DM	2	contributed to conception and design of the study|also participated in data analysis and interpretation|critically revised the manuscript	contributed to conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3334679	22417404	DM	2	contributed to conception and design of the study|also participated in data analysis and interpretation|critically revised the manuscript	also participated in data analysis and interpretation	Analyzed the data	Formal analysis	YES
3334679	22417404	DM	2	contributed to conception and design of the study|also participated in data analysis and interpretation|critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
3334679	22417404	FB	2	participated in study design, statistical analysis and interpretation of data|critically revised the manuscript	participated in study design, statistical analysis and interpretation of data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
3334679	22417404	FB	2	participated in study design, statistical analysis and interpretation of data|critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
3334679	22417404	JO	2	contributed to conception and design of the study|also carried out acquisition, analysis and interpretation of data|participated in drafting the manuscript and revising it	contributed to conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3334679	22417404	JO	2	contributed to conception and design of the study|also carried out acquisition, analysis and interpretation of data|participated in drafting the manuscript and revising it	also carried out acquisition, analysis and interpretation of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3334679	22417404	JO	2	contributed to conception and design of the study|also carried out acquisition, analysis and interpretation of data|participated in drafting the manuscript and revising it	participated in drafting the manuscript and revising it	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3334679	22417404	MRK	2	contributed to conception and design of the study with crucial critics|carried out data analysis and interpretation|critically revised the manuscript	contributed to conception and design of the study with crucial critics	Conceived and designed the experiments	Conceptualization|Methodology	YES
3334679	22417404	MRK	2	contributed to conception and design of the study with crucial critics|carried out data analysis and interpretation|critically revised the manuscript	carried out data analysis and interpretation	Analyzed the data	Formal analysis	YES
3334679	22417404	MRK	2	contributed to conception and design of the study with crucial critics|carried out data analysis and interpretation|critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4398409	25874718	GW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398409	25874718	GW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398409	25874718	GW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398409	25874718	JD	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398409	25874718	JD	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398409	25874718	JD	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398409	25874718	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398409	25874718	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398409	25874718	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398409	25874718	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398409	25874718	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398409	25874718	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398409	25874718	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398409	25874718	MP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398409	25874718	MP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398409	25874718	MP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398409	25874718	PM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398409	25874718	PM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398409	25874718	PM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398409	25874718	RB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398409	25874718	RB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398409	25874718	RB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398409	25874718	RB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5437206	28580006	BZ	2	participated in trait investigations, data analysis, and field experiments	participated in trait investigations, data analysis, and field experiments	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5437206	28580006	CC	2	analyzed the phylogenetic tree	analyzed the phylogenetic tree	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5437206	28580006	JJ	2	performed qtl analyses	performed qtl analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5437206	28580006	KY	2	performed qtl analyses|identified candidate flowering time genes|contributed helpful suggestions	performed qtl analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5437206	28580006	KY	2	performed qtl analyses|identified candidate flowering time genes|contributed helpful suggestions	identified candidate flowering time genes	Performed the experiments	Investigation	YES
5437206	28580006	KY	2	performed qtl analyses|identified candidate flowering time genes|contributed helpful suggestions	contributed helpful suggestions	-	-	NO
5437206	28580006	LC	2	mapped qualitative traits and identified relevant candidate genes	mapped qualitative traits and identified relevant candidate genes	Performed the experiments	Investigation	YES
5437206	28580006	PW	2	designed and managed the project and wrote the manuscript	designed and managed the project and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft	YES
5437206	28580006	TW	2	participated in trait investigations, data analysis, and field experiments	participated in trait investigations, data analysis, and field experiments	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5437206	28580006	WY	2	performed qtl analyses	performed qtl analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5437206	28580006	YL	2	prepared dna samples for rad sequencing, and engaged in data investigation and analysis|performed qtl analyses|identified candidate flowering time genes	prepared dna samples for rad sequencing, and engaged in data investigation and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5437206	28580006	YL	2	prepared dna samples for rad sequencing, and engaged in data investigation and analysis|performed qtl analyses|identified candidate flowering time genes	performed qtl analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5437206	28580006	YL	2	prepared dna samples for rad sequencing, and engaged in data investigation and analysis|performed qtl analyses|identified candidate flowering time genes	identified candidate flowering time genes	Performed the experiments	Investigation	YES
5437206	28580006	YSL	2	participated in trait investigations, data analysis, and field experiments	participated in trait investigations, data analysis, and field experiments	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5437206	28580006	ZY	2	mapped qualitative traits and identified relevant candidate genes	mapped qualitative traits and identified relevant candidate genes	Performed the experiments	Investigation	YES
5781200	23551933	All authors	2	contributed to critical revision of the manuscript and have seen and approved the final version of the manuscript	contributed to critical revision of the manuscript and have seen and approved the final version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5781200	23551933	Graham Reynolds	2	were responsible for data acquisition	were responsible for data acquisition	Performed the experiments	Investigation	YES
5781200	23551933	Gunter Hartel	2	were responsible for study concept and design|were responsible for data analysis, and all authors were responsible for data interpretation	were responsible for study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5781200	23551933	Gunter Hartel	2	were responsible for study concept and design|were responsible for data analysis, and all authors were responsible for data interpretation	were responsible for data analysis, and all authors were responsible for data interpretation	Analyzed the data	Formal analysis	YES
5781200	23551933	Helen Marshall	2	were responsible for data acquisition	were responsible for data acquisition	Performed the experiments	Investigation	YES
5781200	23551933	Jodie McVernon	2	were responsible for data acquisition	were responsible for data acquisition	Performed the experiments	Investigation	YES
5781200	23551933	Leon Heron	2	were responsible for data acquisition	were responsible for data acquisition	Performed the experiments	Investigation	YES
5781200	23551933	Michael Lai	2	were responsible for study concept and design|were responsible for data analysis, and all authors were responsible for data interpretation|was medical monitor for the study	were responsible for study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5781200	23551933	Michael Lai	2	were responsible for study concept and design|were responsible for data analysis, and all authors were responsible for data interpretation|was medical monitor for the study	were responsible for data analysis, and all authors were responsible for data interpretation	Analyzed the data	Formal analysis	YES
5781200	23551933	Michael Lai	2	were responsible for study concept and design|were responsible for data analysis, and all authors were responsible for data interpretation|was medical monitor for the study	was medical monitor for the study	-	Supervision	YES
5781200	23551933	Michael Nissen	2	were responsible for data acquisition	were responsible for data acquisition	Performed the experiments	Investigation	YES
5781200	23551933	Peter Richmond	2	were responsible for data acquisition	were responsible for data acquisition	Performed the experiments	Investigation	YES
5781200	23551933	Raymond Chuk	2	were responsible for data acquisition	were responsible for data acquisition	Performed the experiments	Investigation	YES
5781200	23551933	Robert Booy	2	were responsible for data acquisition	were responsible for data acquisition	Performed the experiments	Investigation	YES
5781200	23551933	Stephen Lambert	2	were responsible for study concept and design|were responsible for data acquisition|were responsible for data analysis, and all authors were responsible for data interpretation|drafted the manuscript	were responsible for study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5781200	23551933	Stephen Lambert	2	were responsible for study concept and design|were responsible for data acquisition|were responsible for data analysis, and all authors were responsible for data interpretation|drafted the manuscript	were responsible for data acquisition	Performed the experiments	Investigation	YES
5781200	23551933	Stephen Lambert	2	were responsible for study concept and design|were responsible for data acquisition|were responsible for data analysis, and all authors were responsible for data interpretation|drafted the manuscript	were responsible for data analysis, and all authors were responsible for data interpretation	Analyzed the data	Formal analysis	YES
5781200	23551933	Stephen Lambert	2	were responsible for study concept and design|were responsible for data acquisition|were responsible for data analysis, and all authors were responsible for data interpretation|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5781200	23551933	Terry Nolan	2	were responsible for data acquisition	were responsible for data acquisition	Performed the experiments	Investigation	YES
5781200	23551933	Tony Walls	2	were responsible for data acquisition	were responsible for data acquisition	Performed the experiments	Investigation	YES
5781200	23551933	Wilson Hu	2	were responsible for study concept and design|were responsible for data analysis, and all authors were responsible for data interpretation	were responsible for study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5781200	23551933	Wilson Hu	2	were responsible for study concept and design|were responsible for data analysis, and all authors were responsible for data interpretation	were responsible for data analysis, and all authors were responsible for data interpretation	Analyzed the data	Formal analysis	YES
6359607	30641932	A.L.	CRediT	Methodology	Methodology	Performed the experiments	Methodology	YES
6359607	30641932	I.T.	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
6359607	30641932	M.A.	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
6359607	30641932	N.Z.	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
6359607	30641932	T.T.	CRediT	Methodology|writing--review and editing	Methodology	Performed the experiments	Methodology	YES
6359607	30641932	T.T.	CRediT	Methodology|writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6359607	30641932	V.S.	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
6359607	30641932	Y.A.	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
3334685	22410286	CS	2	carried out the viral load assays, genotypic drug-resistance test, and subtype analysis	carried out the viral load assays, genotypic drug-resistance test, and subtype analysis	Performed the experiments	Investigation	YES
3334685	22410286	EP	2	carried out the viral load assays, genotypic drug-resistance test, and subtype analysis	carried out the viral load assays, genotypic drug-resistance test, and subtype analysis	Performed the experiments	Investigation	YES
3334685	22410286	SK	2	participated in the design of the study, enrolled patients, collected data on patient history, and drafted the manuscript	participated in the design of the study, enrolled patients, collected data on patient history, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
3334685	22410286	SS	2	participated in the design of the study, enrolled patients, collected data on patient history, and drafted the manuscript	participated in the design of the study, enrolled patients, collected data on patient history, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
3334685	22410286	WC	2	carried out the viral load assays, genotypic drug-resistance test, and subtype analysis	carried out the viral load assays, genotypic drug-resistance test, and subtype analysis	Performed the experiments	Investigation	YES
5006380	27576702	MED	PLoS52	planned the experiments|analyzed the data|wrote the manuscript	planned the experiments	Conceived and designed the experiments	Conceptualization	YES
5006380	27576702	MED	PLoS52	planned the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5006380	27576702	MED	PLoS52	planned the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5006380	27576702	RDN	PLoS52	conceived the study|planned the experiments|did the laboratory work|analyzed the data|wrote the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5006380	27576702	RDN	PLoS52	conceived the study|planned the experiments|did the laboratory work|analyzed the data|wrote the manuscript	planned the experiments	Conceived and designed the experiments	Conceptualization	YES
5006380	27576702	RDN	PLoS52	conceived the study|planned the experiments|did the laboratory work|analyzed the data|wrote the manuscript	did the laboratory work	Performed the experiments	Investigation	YES
5006380	27576702	RDN	PLoS52	conceived the study|planned the experiments|did the laboratory work|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5006380	27576702	RDN	PLoS52	conceived the study|planned the experiments|did the laboratory work|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4398410	25874872	CV	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398410	25874872	DV	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398410	25874872	EM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398410	25874872	ES	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398410	25874872	JP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398410	25874872	JP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398410	25874872	JP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398410	25874872	JR	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398410	25874872	KK	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398410	25874872	KV	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398410	25874872	LV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398410	25874872	LV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398410	25874872	LV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398410	25874872	LV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398410	25874872	MK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398410	25874872	MPE	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398410	25874872	MPE	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398410	25874872	MPE	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398410	25874872	PB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398410	25874872	PC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398410	25874872	PC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398410	25874872	PC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398410	25874872	PVA	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398410	25874872	SC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398410	25874872	SDW	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398410	25874872	VVS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398410	25874872	WDS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398410	25874872	WDS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398410	25874872	WDS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398410	25874872	WT	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5437209	28579990	HC	2	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5437209	28579990	KZ	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5437209	28579990	MZ	2	conducted the experiments	conducted the experiments	Performed the experiments	Investigation	YES
5437209	28579990	QH	2	designed the experiments|revised the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5437209	28579990	QH	2	designed the experiments|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5437209	28579990	ZC	2	conducted the experiments|designed the experiments|analyzed the data and drafted the manuscript	conducted the experiments	Performed the experiments	Investigation	YES
5437209	28579990	ZC	2	conducted the experiments|designed the experiments|analyzed the data and drafted the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5437209	28579990	ZC	2	conducted the experiments|designed the experiments|analyzed the data and drafted the manuscript	analyzed the data and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5437209	28579990	ZY	2	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
3354658	22281054	AK	2	were responsible for data acquisition and interpretation and critical revision of the manuscript	were responsible for data acquisition and interpretation and critical revision of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
3354658	22281054	CKCL	2	were responsible for data acquisition and interpretation and critical revision of the manuscript	were responsible for data acquisition and interpretation and critical revision of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
3354658	22281054	EY	2	were responsible for data acquisition and interpretation and critical revision of the manuscript	were responsible for data acquisition and interpretation and critical revision of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
3354658	22281054	FZ	2	were responsible for data acquisition and interpretation and critical revision of the manuscript	were responsible for data acquisition and interpretation and critical revision of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
3354658	22281054	JYC	2	were responsible for data acquisition and interpretation and critical revision of the manuscript	were responsible for data acquisition and interpretation and critical revision of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
3354658	22281054	JZ	2	was responsible for study design and data analysis	was responsible for study design and data analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
3354658	22281054	LM	2	were responsible for data acquisition and interpretation and critical revision of the manuscript	were responsible for data acquisition and interpretation and critical revision of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
3354658	22281054	MGL	2	undertook study design, data interpretation and critical revision of the manuscript	undertook study design, data interpretation and critical revision of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Review & Editing	YES
3354658	22281054	NK	2	were responsible for data acquisition and interpretation and critical revision of the manuscript	were responsible for data acquisition and interpretation and critical revision of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
3354658	22281054	PCKL	2	were responsible for data acquisition and interpretation and critical revision of the manuscript	were responsible for data acquisition and interpretation and critical revision of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
3354658	22281054	PLL	2	undertook study conception, data interpretation and drafting of the manuscript	undertook study conception, data interpretation and drafting of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
3354658	22281054	PP	2	were responsible for data acquisition and interpretation and critical revision of the manuscript	were responsible for data acquisition and interpretation and critical revision of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
3354658	22281054	RD	2	was responsible for data acquisition and interpretation and critical revision of the manuscript	was responsible for data acquisition and interpretation and critical revision of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
3354658	22281054	SO	2	were responsible for data acquisition and interpretation and critical revision of the manuscript	were responsible for data acquisition and interpretation and critical revision of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
3354658	22281054	SP	2	were responsible for data acquisition and interpretation and critical revision of the manuscript	were responsible for data acquisition and interpretation and critical revision of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
3354658	22281054	SS	2	were responsible for data acquisition and interpretation and critical revision of the manuscript	were responsible for data acquisition and interpretation and critical revision of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
3354658	22281054	TPM	2	were responsible for data acquisition and interpretation and critical revision of the manuscript	were responsible for data acquisition and interpretation and critical revision of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
3354658	22281054	TS	2	were responsible for data acquisition and interpretation and critical revision of the manuscript	were responsible for data acquisition and interpretation and critical revision of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
3354658	22281054	VS	2	were responsible for data acquisition and interpretation and critical revision of the manuscript	were responsible for data acquisition and interpretation and critical revision of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
3354658	22281054	YMAC	2	were responsible for data acquisition and interpretation and critical revision of the manuscript	were responsible for data acquisition and interpretation and critical revision of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
4398411	25875080	AWHC	PLoS5	Initiated this study|Facilitated outbreak control|Leadership and administration support	Initiated this study	Conceived and designed the experiments	Conceptualization	YES
4398411	25875080	AWHC	PLoS5	Initiated this study|Facilitated outbreak control|Leadership and administration support	Facilitated outbreak control	-	-	NO
4398411	25875080	AWHC	PLoS5	Initiated this study|Facilitated outbreak control|Leadership and administration support	Leadership and administration support	-	Project administration|Supervision	YES
4398411	25875080	CCK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Initiated this study|Revised this manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398411	25875080	CCK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Initiated this study|Revised this manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4398411	25875080	CCK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Initiated this study|Revised this manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398411	25875080	CCK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Initiated this study|Revised this manuscript	Initiated this study	Conceived and designed the experiments	Conceptualization	YES
4398411	25875080	CCK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Initiated this study|Revised this manuscript	Revised this manuscript	Wrote the paper	Writing - Review & Editing	YES
4398411	25875080	CKJC	PLoS5	Analyzed the data|Tables figures and structure of this paper|Exchanges|Concerns on public health informatics	Analyzed the data	Analyzed the data	Formal analysis	YES
4398411	25875080	CKJC	PLoS5	Analyzed the data|Tables figures and structure of this paper|Exchanges|Concerns on public health informatics	Tables figures and structure of this paper	-	Visualization	YES
4398411	25875080	CKJC	PLoS5	Analyzed the data|Tables figures and structure of this paper|Exchanges|Concerns on public health informatics	Exchanges	-	-	NO
4398411	25875080	CKJC	PLoS5	Analyzed the data|Tables figures and structure of this paper|Exchanges|Concerns on public health informatics	Concerns on public health informatics	-	Formal analysis	YES
4398411	25875080	HTL	PLoS5	Leadership and administration support	Leadership and administration support	-	Project administration|Supervision	YES
4398411	25875080	HYC	PLoS5	Exchanges|Concerns on public health informatics	Exchanges	-	-	NO
4398411	25875080	HYC	PLoS5	Exchanges|Concerns on public health informatics	Concerns on public health informatics	-	Formal analysis	YES
4398411	25875080	MYY	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Initiated this study|Facilitated outbreak control|Leadership and administration support|Applied general control measures	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398411	25875080	MYY	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Initiated this study|Facilitated outbreak control|Leadership and administration support|Applied general control measures	Analyzed the data	Analyzed the data	Formal analysis	YES
4398411	25875080	MYY	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Initiated this study|Facilitated outbreak control|Leadership and administration support|Applied general control measures	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398411	25875080	MYY	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Initiated this study|Facilitated outbreak control|Leadership and administration support|Applied general control measures	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398411	25875080	MYY	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Initiated this study|Facilitated outbreak control|Leadership and administration support|Applied general control measures	Initiated this study	Conceived and designed the experiments	Conceptualization	YES
4398411	25875080	MYY	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Initiated this study|Facilitated outbreak control|Leadership and administration support|Applied general control measures	Facilitated outbreak control	-	-	NO
4398411	25875080	MYY	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Initiated this study|Facilitated outbreak control|Leadership and administration support|Applied general control measures	Leadership and administration support	-	Project administration|Supervision	YES
4398411	25875080	MYY	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Initiated this study|Facilitated outbreak control|Leadership and administration support|Applied general control measures	Applied general control measures	Performed the experiments	Investigation	YES
4398411	25875080	TCC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Tables figures and structure of this paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398411	25875080	TCC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Tables figures and structure of this paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398411	25875080	TCC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Tables figures and structure of this paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398411	25875080	TCC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Tables figures and structure of this paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398411	25875080	TCC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Tables figures and structure of this paper	Tables figures and structure of this paper	-	Visualization	YES
4398411	25875080	TCW	PLoS5	Analyzed the data|Wrote the paper|Tables figures and structure of this paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398411	25875080	TCW	PLoS5	Analyzed the data|Wrote the paper|Tables figures and structure of this paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398411	25875080	TCW	PLoS5	Analyzed the data|Wrote the paper|Tables figures and structure of this paper	Tables figures and structure of this paper	-	Visualization	YES
4398411	25875080	WWW	PLoS5	Analyzed the data|Tables figures and structure of this paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398411	25875080	WWW	PLoS5	Analyzed the data|Tables figures and structure of this paper	Tables figures and structure of this paper	-	Visualization	YES
4398411	25875080	YRC	PLoS5	Facilitated outbreak control|Leadership and administration support|Applied general control measures	Facilitated outbreak control	-	-	NO
4398411	25875080	YRC	PLoS5	Facilitated outbreak control|Leadership and administration support|Applied general control measures	Leadership and administration support	-	Project administration|Supervision	YES
4398411	25875080	YRC	PLoS5	Facilitated outbreak control|Leadership and administration support|Applied general control measures	Applied general control measures	Performed the experiments	Investigation	YES
4398411	25875080	YTL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398411	25875080	ZRTL	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
3494158	23078769	KP	2	designed the current study concept|conducted the statistical analyses and drafted the manuscript	designed the current study concept	Conceived and designed the experiments	Conceptualization|Methodology	YES
3494158	23078769	KP	2	designed the current study concept|conducted the statistical analyses and drafted the manuscript	conducted the statistical analyses and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3494158	23078769	ML	2	designed the current study concept	designed the current study concept	Conceived and designed the experiments	Conceptualization|Methodology	YES
5437210	28580002	All the authors	2	participated in writing and approved the manuscript for publication	participated in writing and approved the manuscript for publication	Wrote the paper	Writing - Original Draft	YES
5437210	28580002	NPs	2	secondary metabolism	secondary metabolism	-	-	NO
4123554	25132843	Jean Francois Pelletier	2	contributed equally to this work	contributed equally to this work	-	-	NO
4123554	25132843	William E. Thong	2	contributed equally to this work	contributed equally to this work	-	-	NO
5006418	27576499	All authors	2	contributed to the interpretation of the results	contributed to the interpretation of the results	Analyzed the data	Formal analysis	YES
5006418	27576499	CBS	2	designed the study|drafted the manuscript, and all authors contributed to, read, and approved the final manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5006418	27576499	CBS	2	designed the study|drafted the manuscript, and all authors contributed to, read, and approved the final manuscript	drafted the manuscript, and all authors contributed to, read, and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5006418	27576499	CVH	2	designed the study|drafted the manuscript, and all authors contributed to, read, and approved the final manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5006418	27576499	CVH	2	designed the study|drafted the manuscript, and all authors contributed to, read, and approved the final manuscript	drafted the manuscript, and all authors contributed to, read, and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5006418	27576499	FDB	2	drafted the manuscript, and all authors contributed to, read, and approved the final manuscript	drafted the manuscript, and all authors contributed to, read, and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5006418	27576499	PFS	2	drafted the manuscript, and all authors contributed to, read, and approved the final manuscript	drafted the manuscript, and all authors contributed to, read, and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3494160	23078767	All authors	2	contributed and have read and approved the final manuscript	contributed and have read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4398412	25875371	FT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398412	25875371	FT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398412	25875371	FT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398412	25875371	FT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398412	25875371	FT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398412	25875371	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398412	25875371	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398412	25875371	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398412	25875371	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398412	25875371	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398412	25875371	VL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398412	25875371	VL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398412	25875371	VL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398412	25875371	VL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398412	25875371	VL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398412	25875371	VS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398412	25875371	VS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398412	25875371	VS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398412	25875371	VS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398412	25875371	VS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3354554	22629172	Hong-Ren Yu	2	have equally contributed to this paper	have equally contributed to this paper	-	-	NO
3354554	22629172	Wei-Pin Chang	2	have equally contributed to this paper	have equally contributed to this paper	-	-	NO
5437220	28580001	BR	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5437220	28580001	CJ	2	performed bioinformatics analyses|contributed to writing and finalizing the paper	performed bioinformatics analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5437220	28580001	CJ	2	performed bioinformatics analyses|contributed to writing and finalizing the paper	contributed to writing and finalizing the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5437220	28580001	CS	2	performed transcriptomic experiments|performed bioinformatics analyses|contributed to writing and finalizing the paper	performed transcriptomic experiments	Performed the experiments	Investigation	YES
5437220	28580001	CS	2	performed transcriptomic experiments|performed bioinformatics analyses|contributed to writing and finalizing the paper	performed bioinformatics analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5437220	28580001	CS	2	performed transcriptomic experiments|performed bioinformatics analyses|contributed to writing and finalizing the paper	contributed to writing and finalizing the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5437220	28580001	EW	2	designed the study|contributed to writing and finalizing the paper	designed the study	Conceived and designed the experiments	Methodology	YES
5437220	28580001	EW	2	designed the study|contributed to writing and finalizing the paper	contributed to writing and finalizing the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5437220	28580001	JD	2	designed the study|contributed to writing and finalizing the paper	designed the study	Conceived and designed the experiments	Methodology	YES
5437220	28580001	JD	2	designed the study|contributed to writing and finalizing the paper	contributed to writing and finalizing the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5437220	28580001	M-CD	2	designed the study|produced the mapping population seeds|contributed to writing and finalizing the paper	designed the study	Conceived and designed the experiments	Methodology	YES
5437220	28580001	M-CD	2	designed the study|produced the mapping population seeds|contributed to writing and finalizing the paper	produced the mapping population seeds	-	-	NO
5437220	28580001	M-CD	2	designed the study|produced the mapping population seeds|contributed to writing and finalizing the paper	contributed to writing and finalizing the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5437220	28580001	SS	2	carried out the phenotyping experiments|performed bioinformatics analyses|put together the linkage map and conducted the qtl analysis|drafted the manuscript	carried out the phenotyping experiments	Performed the experiments	Investigation	YES
5437220	28580001	SS	2	carried out the phenotyping experiments|performed bioinformatics analyses|put together the linkage map and conducted the qtl analysis|drafted the manuscript	performed bioinformatics analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5437220	28580001	SS	2	carried out the phenotyping experiments|performed bioinformatics analyses|put together the linkage map and conducted the qtl analysis|drafted the manuscript	put together the linkage map and conducted the qtl analysis	Performed the experiments	Investigation	YES
5437220	28580001	SS	2	carried out the phenotyping experiments|performed bioinformatics analyses|put together the linkage map and conducted the qtl analysis|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
3494163	23305651	AH	2	performed data manipulation, statistical analysis, interpretation of results and drafted the manuscript	performed data manipulation, statistical analysis, interpretation of results and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3494163	23305651	PAC	2	originated the study concept and detailed the analysis plan|performed data manipulation, statistical analysis, interpretation of results and drafted the manuscript	originated the study concept and detailed the analysis plan	Conceived and designed the experiments	Conceptualization	YES
3494163	23305651	PAC	2	originated the study concept and detailed the analysis plan|performed data manipulation, statistical analysis, interpretation of results and drafted the manuscript	performed data manipulation, statistical analysis, interpretation of results and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3494163	23305651	RK	2	originated the study concept and detailed the analysis plan|performed data manipulation, statistical analysis, interpretation of results and drafted the manuscript	originated the study concept and detailed the analysis plan	Conceived and designed the experiments	Conceptualization	YES
3494163	23305651	RK	2	originated the study concept and detailed the analysis plan|performed data manipulation, statistical analysis, interpretation of results and drafted the manuscript	performed data manipulation, statistical analysis, interpretation of results and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4402487	25945324	F. Mussano	2	equally contributed to the paper	equally contributed to the paper	-	-	NO
4402487	25945324	G. Schierano	2	equally contributed to the paper	equally contributed to the paper	-	-	NO
4402487	25945324	M. G. Faga	2	equally contributed to the paper	equally contributed to the paper	-	-	NO
5006539	27576450	BL	PLoS52	conducted the field trial to evaluate early maturity traits	conducted the field trial to evaluate early maturity traits	Performed the experiments	Investigation	YES
5006539	27576450	CSW	PLoS52	designed and supervised the research	designed and supervised the research	Conceived and designed the experiments	Methodology|Supervision	YES
5006539	27576450	CXW	PLoS52	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5006539	27576450	CYP	PLoS52	analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5006539	27576450	CYP	PLoS52	analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5006539	27576450	DDG	PLoS52	performed genome sequencing	performed genome sequencing	Performed the experiments	Investigation	YES
5006539	27576450	GZM	PLoS52	conducted the field trial to evaluate early maturity traits	conducted the field trial to evaluate early maturity traits	Performed the experiments	Investigation	YES
5006539	27576450	HLW	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5006539	27576450	HTW	PLoS52	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5006539	27576450	JJS	PLoS52	analyzed the data|conducted the field trial to evaluate early maturity traits|analyzed gene expression by rt pcr|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5006539	27576450	JJS	PLoS52	analyzed the data|conducted the field trial to evaluate early maturity traits|analyzed gene expression by rt pcr|wrote the manuscript	conducted the field trial to evaluate early maturity traits	Performed the experiments	Investigation	YES
5006539	27576450	JJS	PLoS52	analyzed the data|conducted the field trial to evaluate early maturity traits|analyzed gene expression by rt pcr|wrote the manuscript	analyzed gene expression by rt pcr	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5006539	27576450	JJS	PLoS52	analyzed the data|conducted the field trial to evaluate early maturity traits|analyzed gene expression by rt pcr|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5006539	27576450	LBL	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5006539	27576450	LH	PLoS52	performed genome sequencing	performed genome sequencing	Performed the experiments	Investigation	YES
5006539	27576450	MZS	PLoS52	conducted the field trial to evaluate early maturity traits	conducted the field trial to evaluate early maturity traits	Performed the experiments	Investigation	YES
5006539	27576450	SLF	PLoS52	conducted the field trial to evaluate early maturity traits	conducted the field trial to evaluate early maturity traits	Performed the experiments	Investigation	YES
5006539	27576450	SQZ	PLoS52	analyzed gene expression by rt pcr	analyzed gene expression by rt pcr	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5006539	27576450	SXY	PLoS52	designed and supervised the research	designed and supervised the research	Conceived and designed the experiments	Methodology|Supervision	YES
5006539	27576450	XYJ	PLoS52	conducted the field trial to evaluate early maturity traits	conducted the field trial to evaluate early maturity traits	Performed the experiments	Investigation	YES
4398413	25875499	KP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Field research	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398413	25875499	KP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Field research	Performed the experiments	Performed the experiments	Investigation	YES
4398413	25875499	KP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Field research	Analyzed the data	Analyzed the data	Formal analysis	YES
4398413	25875499	KP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Field research	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398413	25875499	KP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Field research	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398413	25875499	KP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Field research	Field research	-	-	NO
4398413	25875499	WP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Field research	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398413	25875499	WP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Field research	Performed the experiments	Performed the experiments	Investigation	YES
4398413	25875499	WP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Field research	Analyzed the data	Analyzed the data	Formal analysis	YES
4398413	25875499	WP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Field research	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398413	25875499	WP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Field research	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398413	25875499	WP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Field research	Field research	-	-	NO
3494173	23305650	ABH	2	designed and performed the statistical analysis of the data	designed and performed the statistical analysis of the data	Conceived and designed the experiments|Analyzed the data	Formal analysis	YES
3494173	23305650	AM	2	participated in data collection	participated in data collection	Performed the experiments	Investigation	YES
3494173	23305650	DP	2	participated in the design of the study, data collection and statistical analysis and drafted the manuscript	participated in the design of the study, data collection and statistical analysis and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
3494173	23305650	IB	2	participated in data collection	participated in data collection	Performed the experiments	Investigation	YES
3494173	23305650	LS	2	participated in the design of the study and helped to draft the manuscript	participated in the design of the study and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3494173	23305650	NM	2	coordinated the study and critically revised the manuscript	coordinated the study and critically revised the manuscript	Wrote the paper	Project administration|Writing - Review & Editing	YES
3494173	23305650	OT	2	participated in data collection	participated in data collection	Performed the experiments	Investigation	YES
3494173	23305650	PM	2	coordinated the study and critically revised the manuscript	coordinated the study and critically revised the manuscript	Wrote the paper	Project administration|Writing - Review & Editing	YES
3494173	23305650	PN	2	coordinated the study and critically revised the manuscript	coordinated the study and critically revised the manuscript	Wrote the paper	Project administration|Writing - Review & Editing	YES
3494173	23305650	SM	2	conceived the study, participated in its design and drafted the manuscript	conceived the study, participated in its design and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
3494173	23305650	TC	2	participated in data collection	participated in data collection	Performed the experiments	Investigation	YES
3494173	23305650	ZA	2	participated in data collection	participated in data collection	Performed the experiments	Investigation	YES
5437370	28579999	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5437370	28579999	GZ	PLoS52	designed the research|revised the paper	designed the research	Conceived and designed the experiments	Methodology	YES
5437370	28579999	GZ	PLoS52	designed the research|revised the paper	revised the paper	Wrote the paper	Writing - Review & Editing	YES
5437370	28579999	HL	PLoS52	performed the experiments|contributed materials and data analysis	performed the experiments	Performed the experiments	Investigation	YES
5437370	28579999	HL	PLoS52	performed the experiments|contributed materials and data analysis	contributed materials and data analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5437370	28579999	HZ	PLoS52	contributed materials and data analysis	contributed materials and data analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5437370	28579999	JY	PLoS52	designed the research|performed the experiments|contributed materials and data analysis|wrote the paper	designed the research	Conceived and designed the experiments	Methodology	YES
5437370	28579999	JY	PLoS52	designed the research|performed the experiments|contributed materials and data analysis|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5437370	28579999	JY	PLoS52	designed the research|performed the experiments|contributed materials and data analysis|wrote the paper	contributed materials and data analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5437370	28579999	JY	PLoS52	designed the research|performed the experiments|contributed materials and data analysis|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5437370	28579999	LV	PLoS52	wrote the paper|revised the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5437370	28579999	LV	PLoS52	wrote the paper|revised the paper	revised the paper	Wrote the paper	Writing - Review & Editing	YES
5437370	28579999	XC	PLoS52	performed the experiments|contributed materials and data analysis	performed the experiments	Performed the experiments	Investigation	YES
5437370	28579999	XC	PLoS52	performed the experiments|contributed materials and data analysis	contributed materials and data analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5437370	28579999	ZL	PLoS52	revised the paper	revised the paper	Wrote the paper	Writing - Review & Editing	YES
6359642	30625999	A.J.A.	2	contributed to the writing and editing of the paper	contributed to the writing and editing of the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6359642	30625999	C.O.S.	2	contributed to the writing and editing of the paper	contributed to the writing and editing of the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6359642	30625999	C.R.	2	contributed to the writing and editing of the paper	contributed to the writing and editing of the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6359642	30625999	J.L.	2	contributed to the writing and editing of the paper	contributed to the writing and editing of the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6359642	30625999	J.O.P.	2	contributed to the writing and editing of the paper	contributed to the writing and editing of the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6359642	30625999	M.M.G.	2	contributed to the writing and editing of the paper	contributed to the writing and editing of the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5006594	27577050	ALG	2	together conceived and designed the study|performed data analyses and drafted the manuscript	together conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5006594	27577050	ALG	2	together conceived and designed the study|performed data analyses and drafted the manuscript	performed data analyses and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5006594	27577050	All authors	2	contributed to and approved content comprising the final manuscript	contributed to and approved content comprising the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5006594	27577050	CJR	2	provided samples from which data were analysed	provided samples from which data were analysed	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5006594	27577050	ES	2	together conceived and designed the study	together conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398416	25874801	AD	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398416	25874801	BSP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398416	25874801	BSP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398416	25874801	BSP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398416	25874801	BSP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398416	25874801	GS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398416	25874801	HW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398416	25874801	HW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398416	25874801	HW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398416	25874801	HW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398416	25874801	LB	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4398416	25874801	LB	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4398416	25874801	ML	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398416	25874801	ST	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398416	25874801	ST	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398416	25874801	ST	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398416	25874801	ST	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398416	25874801	ST	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3494174	23078768	AK	2	analysed data and wrote first draft of the manuscript	analysed data and wrote first draft of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3494174	23078768	All authors	2	have read and approved the final version	have read and approved the final version	-	-	NO
3494174	23078768	MM	2	developed study protocol, advised on data analysis, interpretation and outlined manuscript concept and substantially reviewed the manuscript	developed study protocol, advised on data analysis, interpretation and outlined manuscript concept and substantially reviewed the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
3494174	23078768	RH	2	prepared the study proposal, collected data and interpreted the findings, and reviewed the manuscript	prepared the study proposal, collected data and interpreted the findings, and reviewed the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
3494174	23078768	RL	2	interpreted data, substantially reviewed and provided technical inputs to the manuscript	interpreted data, substantially reviewed and provided technical inputs to the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
3494174	23078768	TN	2	developed study protocol, supervised data collection, analysed data and interpreted the findings, complied authors and reviewers comments and revised the manuscript	developed study protocol, supervised data collection, analysed data and interpreted the findings, complied authors and reviewers comments and revised the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
3494174	23078768	VT	2	performed data management and analysis and reviewing of the manuscript	performed data management and analysis and reviewing of the manuscript	Analyzed the data|Wrote the paper	Data curation|Formal analysis|Writing - Review & Editing	YES
3494174	23078768	WF	2	involved in supervising data collection, interpreting findings and reviewing of the manuscript	involved in supervising data collection, interpreting findings and reviewing of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Supervision|Writing - Review & Editing	YES
6359657	30583601	L.C.	CRediT	Methodology	Methodology	Performed the experiments	Methodology	YES
6359657	30583601	L.X.	CRediT	Resources|Project administration|Writing-review & editing|Funding acquisition	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6359657	30583601	L.X.	CRediT	Resources|Project administration|Writing-review & editing|Funding acquisition	Project administration	-	Project administration	YES
6359657	30583601	L.X.	CRediT	Resources|Project administration|Writing-review & editing|Funding acquisition	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6359657	30583601	L.X.	CRediT	Resources|Project administration|Writing-review & editing|Funding acquisition	Funding acquisition	-	Funding acquisition	YES
6359657	30583601	M.C.	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
6359657	30583601	N.Z.	CRediT	Conceptualization|Data curation	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6359657	30583601	N.Z.	CRediT	Conceptualization|Data curation	Data curation	Analyzed the data	Data curation	YES
6359657	30583601	S.L.	CRediT	Writing-review & editing	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6359657	30583601	W.Z.	CRediT	Conceptualization|Formal analysis|Writing-original draft preparation	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6359657	30583601	W.Z.	CRediT	Conceptualization|Formal analysis|Writing-original draft preparation	Formal analysis	Analyzed the data	Formal analysis	YES
6359657	30583601	W.Z.	CRediT	Conceptualization|Formal analysis|Writing-original draft preparation	Writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
5437371	28579991	QY	2	collected population samples	collected population samples	Performed the experiments	Investigation	YES
5437371	28579991	ST	2	designed the study and wrote and revised the manuscript	designed the study and wrote and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5437371	28579991	SW	2	performed experiments, analyzed the data, and wrote the manuscript	performed experiments, analyzed the data, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5437371	28579991	YL	2	collected population samples	collected population samples	Performed the experiments	Investigation	YES
5006608	27577199	AC	2	conceived and designed the project	conceived and designed the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5006608	27577199	DZ	2	conceived and designed the project|drafted and revised the manuscript	conceived and designed the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5006608	27577199	DZ	2	conceived and designed the project|drafted and revised the manuscript	drafted and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5006608	27577199	JW	2	cultured bacteria and extracted genomic dna	cultured bacteria and extracted genomic dna	Performed the experiments	Investigation	YES
5006608	27577199	KS	2	assembled and annotated the genomes	assembled and annotated the genomes	-	-	NO
5006608	27577199	ML	2	assembled and annotated the genomes	assembled and annotated the genomes	-	-	NO
5006608	27577199	MW	2	cultured bacteria and extracted genomic dna	cultured bacteria and extracted genomic dna	Performed the experiments	Investigation	YES
5006608	27577199	QY	2	performed comparative genomics analysis	performed comparative genomics analysis	Performed the experiments	Investigation	YES
5006608	27577199	RJ	2	assembled and annotated the genomes	assembled and annotated the genomes	-	-	NO
5006608	27577199	SC	2	assembled and annotated the genomes	assembled and annotated the genomes	-	-	NO
5006608	27577199	WZ	2	cultured bacteria and extracted genomic dna	cultured bacteria and extracted genomic dna	Performed the experiments	Investigation	YES
5006608	27577199	XC	2	cultured bacteria and extracted genomic dna	cultured bacteria and extracted genomic dna	Performed the experiments	Investigation	YES
5006608	27577199	XS	2	cultured bacteria and extracted genomic dna	cultured bacteria and extracted genomic dna	Performed the experiments	Investigation	YES
5006608	27577199	XY	2	performed comparative genomics analysis|drafted and revised the manuscript	performed comparative genomics analysis	Performed the experiments	Investigation	YES
5006608	27577199	XY	2	performed comparative genomics analysis|drafted and revised the manuscript	drafted and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5006608	27577199	YH	2	cultured bacteria and extracted genomic dna	cultured bacteria and extracted genomic dna	Performed the experiments	Investigation	YES
5006608	27577199	YW	2	performed comparative genomics analysis	performed comparative genomics analysis	Performed the experiments	Investigation	YES
5006608	27577199	YZ	2	performed comparative genomics analysis	performed comparative genomics analysis	Performed the experiments	Investigation	YES
4398417	25875335	GY	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4398417	25875335	JD	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398417	25875335	JY	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398417	25875335	JY	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398417	25875335	JY	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398417	25875335	LC	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4398417	25875335	ML	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4398417	25875335	ML	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398417	25875335	RF	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398417	25875335	TL	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398417	25875335	WR	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398417	25875335	YY	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398417	25875335	YZ	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5437372	28579992	CS	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5437372	28579992	CS	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5437372	28579992	CY	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5437372	28579992	ES	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5437372	28579992	TY	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5437372	28579992	XJ	PLoS5	Conceived and designed the experiments, performed the experiments, and analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments, performed the experiments, and analyzed the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation|Methodology	YES
5437372	28579992	XJ	PLoS5	Conceived and designed the experiments, performed the experiments, and analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5437372	28579992	XJ	PLoS5	Conceived and designed the experiments, performed the experiments, and analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398419	25874452	EKM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398419	25874452	EKM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398419	25874452	EKM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398419	25874452	EM	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398419	25874452	JPC	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398419	25874452	JPC	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398419	25874452	JS	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398419	25874452	NM	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398419	25874452	NM	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398419	25874452	NR	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398419	25874452	NR	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398419	25874452	RH	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398419	25874452	RH	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5781208	23122369	AO	2	wrote the first draft of the manuscript|were the chief members of collaborative study group and conducted the study, interpreted the data, and made consensus regarding the cause of death	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
5781208	23122369	AO	2	wrote the first draft of the manuscript|were the chief members of collaborative study group and conducted the study, interpreted the data, and made consensus regarding the cause of death	were the chief members of collaborative study group and conducted the study, interpreted the data, and made consensus regarding the cause of death	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5781208	23122369	CT	2	were the members of the collaborative study group|visited the hospital and interviewed the attending pediatricians of the patient in cooperation with the chief members	were the members of the collaborative study group	-	-	NO
5781208	23122369	CT	2	were the members of the collaborative study group|visited the hospital and interviewed the attending pediatricians of the patient in cooperation with the chief members	visited the hospital and interviewed the attending pediatricians of the patient in cooperation with the chief members	Performed the experiments	Investigation	YES
5781208	23122369	HK	2	were the chief members of collaborative study group and conducted the study, interpreted the data, and made consensus regarding the cause of death	were the chief members of collaborative study group and conducted the study, interpreted the data, and made consensus regarding the cause of death	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5781208	23122369	JF	2	were the members of the collaborative study group|visited the hospital and interviewed the attending pediatricians of the patient in cooperation with the chief members	were the members of the collaborative study group	-	-	NO
5781208	23122369	JF	2	were the members of the collaborative study group|visited the hospital and interviewed the attending pediatricians of the patient in cooperation with the chief members	visited the hospital and interviewed the attending pediatricians of the patient in cooperation with the chief members	Performed the experiments	Investigation	YES
5781208	23122369	NK	2	supervised the study and corrected the manuscript	supervised the study and corrected the manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
5781208	23122369	OS	2	were the members of the collaborative study group|visited the hospital and interviewed the attending pediatricians of the patient in cooperation with the chief members	were the members of the collaborative study group	-	-	NO
5781208	23122369	OS	2	were the members of the collaborative study group|visited the hospital and interviewed the attending pediatricians of the patient in cooperation with the chief members	visited the hospital and interviewed the attending pediatricians of the patient in cooperation with the chief members	Performed the experiments	Investigation	YES
5781208	23122369	SK	2	were the members of the collaborative study group|visited the hospital and interviewed the attending pediatricians of the patient in cooperation with the chief members	were the members of the collaborative study group	-	-	NO
5781208	23122369	SK	2	were the members of the collaborative study group|visited the hospital and interviewed the attending pediatricians of the patient in cooperation with the chief members	visited the hospital and interviewed the attending pediatricians of the patient in cooperation with the chief members	Performed the experiments	Investigation	YES
5781208	23122369	SN	2	were the chief members of collaborative study group and conducted the study, interpreted the data, and made consensus regarding the cause of death	were the chief members of collaborative study group and conducted the study, interpreted the data, and made consensus regarding the cause of death	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5781208	23122369	ST	2	supervised the study and corrected the manuscript	supervised the study and corrected the manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
5781208	23122369	TI	2	were the members of the collaborative study group|visited the hospital and interviewed the attending pediatricians of the patient in cooperation with the chief members	were the members of the collaborative study group	-	-	NO
5781208	23122369	TI	2	were the members of the collaborative study group|visited the hospital and interviewed the attending pediatricians of the patient in cooperation with the chief members	visited the hospital and interviewed the attending pediatricians of the patient in cooperation with the chief members	Performed the experiments	Investigation	YES
5781208	23122369	TM	2	were the members of the collaborative study group|visited the hospital and interviewed the attending pediatricians of the patient in cooperation with the chief members|supervised the study and corrected the manuscript	were the members of the collaborative study group	-	-	NO
5781208	23122369	TM	2	were the members of the collaborative study group|visited the hospital and interviewed the attending pediatricians of the patient in cooperation with the chief members|supervised the study and corrected the manuscript	visited the hospital and interviewed the attending pediatricians of the patient in cooperation with the chief members	Performed the experiments	Investigation	YES
5781208	23122369	TM	2	were the members of the collaborative study group|visited the hospital and interviewed the attending pediatricians of the patient in cooperation with the chief members|supervised the study and corrected the manuscript	supervised the study and corrected the manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
5006616	27577548	ASM	2	participated in the design of the study|performed annotation, distribution analysis, expression quantification, lineage analysis and prepared the manuscript	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
5006616	27577548	ASM	2	participated in the design of the study|performed annotation, distribution analysis, expression quantification, lineage analysis and prepared the manuscript	performed annotation, distribution analysis, expression quantification, lineage analysis and prepared the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Formal analysis|Investigation|Writing - Original Draft	YES
5006616	27577548	All authors	2	critically reviewed and approved the final revision of the manuscript	critically reviewed and approved the final revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5006616	27577548	DWB	2	supervised the work, design and initial concept of the study	supervised the work, design and initial concept of the study	Conceived and designed the experiments	Conceptualization|Methodology|Supervision	YES
5006616	27577548	JEF	2	participated in the design of the study	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
5006616	27577548	PMH	2	participated in the design of the study	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
6409530	30781728	C.D.	CRediT	Conceptualization|data curation|writing--original draft preparation	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6409530	30781728	C.D.	CRediT	Conceptualization|data curation|writing--original draft preparation	data curation	Analyzed the data	Data curation	YES
6409530	30781728	C.D.	CRediT	Conceptualization|data curation|writing--original draft preparation	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6409530	30781728	L.A.	CRediT	supervision|funding acquisition	supervision	-	Supervision	YES
6409530	30781728	L.A.	CRediT	supervision|funding acquisition	funding acquisition	-	Funding acquisition	YES
6409530	30781728	P.C.	CRediT	methodology|validation|investigation	methodology	Performed the experiments	Methodology	YES
6409530	30781728	P.C.	CRediT	methodology|validation|investigation	validation	Performed the experiments	Validation	YES
6409530	30781728	P.C.	CRediT	methodology|validation|investigation	investigation	Performed the experiments	Investigation	YES
6409530	30781728	R.A.	CRediT	methodology|validation|investigation	methodology	Performed the experiments	Methodology	YES
6409530	30781728	R.A.	CRediT	methodology|validation|investigation	validation	Performed the experiments	Validation	YES
6409530	30781728	R.A.	CRediT	methodology|validation|investigation	investigation	Performed the experiments	Investigation	YES
6409530	30781728	S.C.	CRediT	Conceptualization|formal analysis|data curation|writing--original draft preparation	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6409530	30781728	S.C.	CRediT	Conceptualization|formal analysis|data curation|writing--original draft preparation	formal analysis	Analyzed the data	Formal analysis	YES
6409530	30781728	S.C.	CRediT	Conceptualization|formal analysis|data curation|writing--original draft preparation	data curation	Analyzed the data	Data curation	YES
6409530	30781728	S.C.	CRediT	Conceptualization|formal analysis|data curation|writing--original draft preparation	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6409530	30781728	T.C.	CRediT	methodology|validation|investigation	methodology	Performed the experiments	Methodology	YES
6409530	30781728	T.C.	CRediT	methodology|validation|investigation	validation	Performed the experiments	Validation	YES
6409530	30781728	T.C.	CRediT	methodology|validation|investigation	investigation	Performed the experiments	Investigation	YES
6409530	30781728	V.G.	CRediT	Conceptualization|formal analysis|resources|data curation|writing--original draft preparation|writing--review and editing|supervision|funding acquisition	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6409530	30781728	V.G.	CRediT	Conceptualization|formal analysis|resources|data curation|writing--original draft preparation|writing--review and editing|supervision|funding acquisition	formal analysis	Analyzed the data	Formal analysis	YES
6409530	30781728	V.G.	CRediT	Conceptualization|formal analysis|resources|data curation|writing--original draft preparation|writing--review and editing|supervision|funding acquisition	resources	Contributed reagents/materials/analysis tools	Resources	YES
6409530	30781728	V.G.	CRediT	Conceptualization|formal analysis|resources|data curation|writing--original draft preparation|writing--review and editing|supervision|funding acquisition	data curation	Analyzed the data	Data curation	YES
6409530	30781728	V.G.	CRediT	Conceptualization|formal analysis|resources|data curation|writing--original draft preparation|writing--review and editing|supervision|funding acquisition	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6409530	30781728	V.G.	CRediT	Conceptualization|formal analysis|resources|data curation|writing--original draft preparation|writing--review and editing|supervision|funding acquisition	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6409530	30781728	V.G.	CRediT	Conceptualization|formal analysis|resources|data curation|writing--original draft preparation|writing--review and editing|supervision|funding acquisition	supervision	-	Supervision	YES
6409530	30781728	V.G.	CRediT	Conceptualization|formal analysis|resources|data curation|writing--original draft preparation|writing--review and editing|supervision|funding acquisition	funding acquisition	-	Funding acquisition	YES
6409530	30781728	VG	CRediT	methodology	methodology	Performed the experiments	Methodology	YES
5437378	28580000	AC	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5437378	28580000	AC	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5437378	28580000	DR	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5437378	28580000	JS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5437378	28580000	LP	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5437378	28580000	LP	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5437378	28580000	NM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5437378	28580000	RN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5437378	28580000	RN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
5437378	28580000	RN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5437378	28580000	RN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5437378	28580000	SP	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5437378	28580000	SP	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5437378	28580000	WN	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4402576	25945338	Xingxiao Lu	2	contributed equally to this work	contributed equally to this work	-	-	NO
4402576	25945338	Yuqun Shan	2	contributed equally to this work	contributed equally to this work	-	-	NO
5781209	23279922	AF	2	have made substantial contribution to conception and design, or acquisition of data, or analysis and interpretation of data|have drafted the submitted article or revised it critically for important intellectual content|have provided final approval of the version to be published	have made substantial contribution to conception and design, or acquisition of data, or analysis and interpretation of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
5781209	23279922	AF	2	have made substantial contribution to conception and design, or acquisition of data, or analysis and interpretation of data|have drafted the submitted article or revised it critically for important intellectual content|have provided final approval of the version to be published	have drafted the submitted article or revised it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5781209	23279922	AF	2	have made substantial contribution to conception and design, or acquisition of data, or analysis and interpretation of data|have drafted the submitted article or revised it critically for important intellectual content|have provided final approval of the version to be published	have provided final approval of the version to be published	-	-	NO
5781209	23279922	DMB	2	have made substantial contribution to conception and design, or acquisition of data, or analysis and interpretation of data|have provided final approval of the version to be published	have made substantial contribution to conception and design, or acquisition of data, or analysis and interpretation of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
5781209	23279922	DMB	2	have made substantial contribution to conception and design, or acquisition of data, or analysis and interpretation of data|have provided final approval of the version to be published	have provided final approval of the version to be published	-	-	NO
5781209	23279922	EDK	2	have made substantial contribution to conception and design, or acquisition of data, or analysis and interpretation of data|have drafted the submitted article or revised it critically for important intellectual content|have provided final approval of the version to be published|is guarantor of the study	have made substantial contribution to conception and design, or acquisition of data, or analysis and interpretation of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
5781209	23279922	EDK	2	have made substantial contribution to conception and design, or acquisition of data, or analysis and interpretation of data|have drafted the submitted article or revised it critically for important intellectual content|have provided final approval of the version to be published|is guarantor of the study	have drafted the submitted article or revised it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5781209	23279922	EDK	2	have made substantial contribution to conception and design, or acquisition of data, or analysis and interpretation of data|have drafted the submitted article or revised it critically for important intellectual content|have provided final approval of the version to be published|is guarantor of the study	have provided final approval of the version to be published	-	-	NO
5781209	23279922	EDK	2	have made substantial contribution to conception and design, or acquisition of data, or analysis and interpretation of data|have drafted the submitted article or revised it critically for important intellectual content|have provided final approval of the version to be published|is guarantor of the study	is guarantor of the study	-	-	NO
5781209	23279922	JN	2	have made substantial contribution to conception and design, or acquisition of data, or analysis and interpretation of data|have provided final approval of the version to be published	have made substantial contribution to conception and design, or acquisition of data, or analysis and interpretation of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
5781209	23279922	JN	2	have made substantial contribution to conception and design, or acquisition of data, or analysis and interpretation of data|have provided final approval of the version to be published	have provided final approval of the version to be published	-	-	NO
5781209	23279922	KW	2	have made substantial contribution to conception and design, or acquisition of data, or analysis and interpretation of data|have provided final approval of the version to be published	have made substantial contribution to conception and design, or acquisition of data, or analysis and interpretation of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
5781209	23279922	KW	2	have made substantial contribution to conception and design, or acquisition of data, or analysis and interpretation of data|have provided final approval of the version to be published	have provided final approval of the version to be published	-	-	NO
5781209	23279922	LF	2	have made substantial contribution to conception and design, or acquisition of data, or analysis and interpretation of data|have drafted the submitted article or revised it critically for important intellectual content|have provided final approval of the version to be published	have made substantial contribution to conception and design, or acquisition of data, or analysis and interpretation of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
5781209	23279922	LF	2	have made substantial contribution to conception and design, or acquisition of data, or analysis and interpretation of data|have drafted the submitted article or revised it critically for important intellectual content|have provided final approval of the version to be published	have drafted the submitted article or revised it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5781209	23279922	LF	2	have made substantial contribution to conception and design, or acquisition of data, or analysis and interpretation of data|have drafted the submitted article or revised it critically for important intellectual content|have provided final approval of the version to be published	have provided final approval of the version to be published	-	-	NO
5781209	23279922	LK	2	have made substantial contribution to conception and design, or acquisition of data, or analysis and interpretation of data|have provided final approval of the version to be published	have made substantial contribution to conception and design, or acquisition of data, or analysis and interpretation of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
5781209	23279922	LK	2	have made substantial contribution to conception and design, or acquisition of data, or analysis and interpretation of data|have provided final approval of the version to be published	have provided final approval of the version to be published	-	-	NO
5781209	23279922	MAJ	2	have made substantial contribution to conception and design, or acquisition of data, or analysis and interpretation of data|have drafted the submitted article or revised it critically for important intellectual content|have provided final approval of the version to be published	have made substantial contribution to conception and design, or acquisition of data, or analysis and interpretation of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
5781209	23279922	MAJ	2	have made substantial contribution to conception and design, or acquisition of data, or analysis and interpretation of data|have drafted the submitted article or revised it critically for important intellectual content|have provided final approval of the version to be published	have drafted the submitted article or revised it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5781209	23279922	MAJ	2	have made substantial contribution to conception and design, or acquisition of data, or analysis and interpretation of data|have drafted the submitted article or revised it critically for important intellectual content|have provided final approval of the version to be published	have provided final approval of the version to be published	-	-	NO
5781209	23279922	MK	2	have made substantial contribution to conception and design, or acquisition of data, or analysis and interpretation of data|have provided final approval of the version to be published	have made substantial contribution to conception and design, or acquisition of data, or analysis and interpretation of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
5781209	23279922	MK	2	have made substantial contribution to conception and design, or acquisition of data, or analysis and interpretation of data|have provided final approval of the version to be published	have provided final approval of the version to be published	-	-	NO
5781209	23279922	MR	2	have made substantial contribution to conception and design, or acquisition of data, or analysis and interpretation of data|have drafted the submitted article or revised it critically for important intellectual content|have provided final approval of the version to be published	have made substantial contribution to conception and design, or acquisition of data, or analysis and interpretation of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
5781209	23279922	MR	2	have made substantial contribution to conception and design, or acquisition of data, or analysis and interpretation of data|have drafted the submitted article or revised it critically for important intellectual content|have provided final approval of the version to be published	have drafted the submitted article or revised it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5781209	23279922	MR	2	have made substantial contribution to conception and design, or acquisition of data, or analysis and interpretation of data|have drafted the submitted article or revised it critically for important intellectual content|have provided final approval of the version to be published	have provided final approval of the version to be published	-	-	NO
5781209	23279922	SRZ	2	have made substantial contribution to conception and design, or acquisition of data, or analysis and interpretation of data|have provided final approval of the version to be published	have made substantial contribution to conception and design, or acquisition of data, or analysis and interpretation of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
5781209	23279922	SRZ	2	have made substantial contribution to conception and design, or acquisition of data, or analysis and interpretation of data|have provided final approval of the version to be published	have provided final approval of the version to be published	-	-	NO
5781209	23279922	W-JS	2	have made substantial contribution to conception and design, or acquisition of data, or analysis and interpretation of data|have provided final approval of the version to be published	have made substantial contribution to conception and design, or acquisition of data, or analysis and interpretation of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
5781209	23279922	W-JS	2	have made substantial contribution to conception and design, or acquisition of data, or analysis and interpretation of data|have provided final approval of the version to be published	have provided final approval of the version to be published	-	-	NO
4398420	25874715	HI	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398420	25874715	HI	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398420	25874715	HM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398420	25874715	HM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398420	25874715	HM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398420	25874715	HT	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398420	25874715	HT	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398420	25874715	KA	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398420	25874715	KF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398420	25874715	KF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398420	25874715	KF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398420	25874715	KF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398420	25874715	KF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398420	25874715	KY	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Wrote the paper|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398420	25874715	KY	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Wrote the paper|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398420	25874715	KY	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Wrote the paper|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398420	25874715	KY	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Wrote the paper|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398420	25874715	KY	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Wrote the paper|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398420	25874715	KY	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Wrote the paper|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398420	25874715	KY	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Wrote the paper|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398420	25874715	KY	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Wrote the paper|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398420	25874715	KY	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Wrote the paper|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398420	25874715	KY	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Wrote the paper|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398420	25874715	SN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398420	25874715	SN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398420	25874715	SN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398420	25874715	SN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398420	25874715	SN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398420	25874715	TK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398420	25874715	TK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398420	25874715	TK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398420	25874715	TK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398420	25874715	TK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6409538	30736486	F.R.	2	revised and edited the manuscript	revised and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
6409538	30736486	P.E.	2	contributed to revision of the manuscript	contributed to revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
6409538	30736486	S.F.	2	conceived and wrote the manuscript	conceived and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5007679	27581076	JFP	2	participated in its design and help to draft the manuscript	participated in its design and help to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
5007679	27581076	JS	2	conceived of study, participated in its design and coordination, and wrote the manuscript	conceived of study, participated in its design and coordination, and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
5007679	27581076	LGS	2	participated in the irradiation of samples, and in its preparation for microarray and western blot analysis	participated in the irradiation of samples, and in its preparation for microarray and western blot analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5007679	27581076	MM	2	participated in the irradiation of samples, and in its preparation for microarray and western blot analysis	participated in the irradiation of samples, and in its preparation for microarray and western blot analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5007679	27581076	PFN	2	carried out all statistical analyses	carried out all statistical analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5007679	27581076	PLN	2	carried out western blot and quantitative real-time rt pcr experiments	carried out western blot and quantitative real-time rt pcr experiments	Performed the experiments	Investigation	YES
5437379	28580003	AB	2	drafted the manuscript|collected background information	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5437379	28580003	AB	2	drafted the manuscript|collected background information	collected background information	Performed the experiments	Investigation	YES
5437379	28580003	AD	2	critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5437379	28580003	AS	2	drafted the manuscript|critically revised the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5437379	28580003	AS	2	drafted the manuscript|critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5437379	28580003	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5437379	28580003	OG	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5437379	28580003	PJ	2	critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5437379	28580003	SB	2	drafted the manuscript|collected background information	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5437379	28580003	SB	2	drafted the manuscript|collected background information	collected background information	Performed the experiments	Investigation	YES
5437379	28580003	SG	2	drafted the manuscript|critically revised the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5437379	28580003	SG	2	drafted the manuscript|critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
6409561	30781880	B.L.	CRediT	Conceptualization|methodology|writing-original draft preparation	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6409561	30781880	B.L.	CRediT	Conceptualization|methodology|writing-original draft preparation	methodology	Performed the experiments	Methodology	YES
6409561	30781880	B.L.	CRediT	Conceptualization|methodology|writing-original draft preparation	writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
6409561	30781880	C.M.	CRediT	Conceptualization|methodology|writing-original draft preparation|Writing-review & editing|Funding acquisition	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6409561	30781880	C.M.	CRediT	Conceptualization|methodology|writing-original draft preparation|Writing-review & editing|Funding acquisition	methodology	Performed the experiments	Methodology	YES
6409561	30781880	C.M.	CRediT	Conceptualization|methodology|writing-original draft preparation|Writing-review & editing|Funding acquisition	writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
6409561	30781880	C.M.	CRediT	Conceptualization|methodology|writing-original draft preparation|Writing-review & editing|Funding acquisition	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6409561	30781880	C.M.	CRediT	Conceptualization|methodology|writing-original draft preparation|Writing-review & editing|Funding acquisition	Funding acquisition	-	Funding acquisition	YES
6409561	30781880	E.O.	CRediT	Conceptualization|methodology|writing-original draft preparation|Writing-review & editing|Funding acquisition	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6409561	30781880	E.O.	CRediT	Conceptualization|methodology|writing-original draft preparation|Writing-review & editing|Funding acquisition	methodology	Performed the experiments	Methodology	YES
6409561	30781880	E.O.	CRediT	Conceptualization|methodology|writing-original draft preparation|Writing-review & editing|Funding acquisition	writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
6409561	30781880	E.O.	CRediT	Conceptualization|methodology|writing-original draft preparation|Writing-review & editing|Funding acquisition	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6409561	30781880	E.O.	CRediT	Conceptualization|methodology|writing-original draft preparation|Writing-review & editing|Funding acquisition	Funding acquisition	-	Funding acquisition	YES
6409561	30781880	U.K.	CRediT	methodology|writing-original draft preparation	methodology	Performed the experiments	Methodology	YES
6409561	30781880	U.K.	CRediT	methodology|writing-original draft preparation	writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
5007699	27580945	AS	2	authors participated in editing the manuscript	authors participated in editing the manuscript	Wrote the paper	Writing - Review & Editing	YES
5007699	27580945	All	2	authors participated in editing the manuscript	authors participated in editing the manuscript	Wrote the paper	Writing - Review & Editing	YES
5007699	27580945	JGC	2	authors participated in editing the manuscript	authors participated in editing the manuscript	Wrote the paper	Writing - Review & Editing	YES
5007699	27580945	JJ	2	authors participated in editing the manuscript	authors participated in editing the manuscript	Wrote the paper	Writing - Review & Editing	YES
5007699	27580945	MK	2	authors participated in editing the manuscript	authors participated in editing the manuscript	Wrote the paper	Writing - Review & Editing	YES
5007699	27580945	SJ	2	authors participated in editing the manuscript	authors participated in editing the manuscript	Wrote the paper	Writing - Review & Editing	YES
5007699	27580945	YY	2	authors participated in editing the manuscript	authors participated in editing the manuscript	Wrote the paper	Writing - Review & Editing	YES
4398421	25875084	CS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398421	25875084	CS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398421	25875084	CS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398421	25875084	EL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398421	25875084	EL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398421	25875084	EL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398421	25875084	EL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398421	25875084	FT	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398421	25875084	FT	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398421	25875084	FT	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398421	25875084	GB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398421	25875084	GB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398421	25875084	GB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398421	25875084	GVW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398421	25875084	GVW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398421	25875084	GVW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398421	25875084	GVW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398421	25875084	JG	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398421	25875084	JG	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398421	25875084	JG	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398421	25875084	MAS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398421	25875084	MAS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398421	25875084	MAS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398421	25875084	MAS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398421	25875084	SR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398421	25875084	SR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398421	25875084	SR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398421	25875084	SR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398421	25875084	SR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5437697	28580005	JL	2	contributed to materials collection, dna extraction, and manuscript revision	contributed to materials collection, dna extraction, and manuscript revision	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Resources|Writing - Review & Editing	YES
5437697	28580005	XF	2	was in charge of finishing the molecular genetic studies, performing the data analysis and writing the manuscript	was in charge of finishing the molecular genetic studies, performing the data analysis and writing the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5437697	28580005	XG	2	designed the study, collected research materials and drafted the manuscript	designed the study, collected research materials and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5437697	28580005	Y-CC	2	designed the study, collected research materials and drafted the manuscript	designed the study, collected research materials and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
6409563	30781383	A.M.	CRediT	Funding acquisition	Funding acquisition	-	Funding acquisition	YES
6409563	30781383	D.I.	CRediT	Investigation|Project administration	Investigation	Performed the experiments	Investigation	YES
6409563	30781383	D.I.	CRediT	Investigation|Project administration	Project administration	-	Project administration	YES
6409563	30781383	D.K.	CRediT	Funding acquisition	Funding acquisition	-	Funding acquisition	YES
6409563	30781383	F.H.	CRediT	Conceptualization|Writing-review and editing|Supervision	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6409563	30781383	F.H.	CRediT	Conceptualization|Writing-review and editing|Supervision	Writing-review and editing	Wrote the paper	Writing - Review & Editing	YES
6409563	30781383	F.H.	CRediT	Conceptualization|Writing-review and editing|Supervision	Supervision	-	Supervision	YES
6409563	30781383	M.A.	CRediT	Conceptualization|Investigation|Writing-review and editing|Project administration	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6409563	30781383	M.A.	CRediT	Conceptualization|Investigation|Writing-review and editing|Project administration	Investigation	Performed the experiments	Investigation	YES
6409563	30781383	M.A.	CRediT	Conceptualization|Investigation|Writing-review and editing|Project administration	Writing-review and editing	Wrote the paper	Writing - Review & Editing	YES
6409563	30781383	M.A.	CRediT	Conceptualization|Investigation|Writing-review and editing|Project administration	Project administration	-	Project administration	YES
6409563	30781383	M.G.	CRediT	Visualization	Visualization	Analyzed the data	Visualization	YES
6409563	30781383	M.O.	CRediT	Visualization	Visualization	Analyzed the data	Visualization	YES
6409563	30781383	R.T.	CRediT	Project administration	Project administration	-	Project administration	YES
6409563	30781383	Yasuyuki Mizukai	CRediT	Supervision	Supervision	-	Supervision	YES
6409563	30781383	Yuji Maezaki	CRediT	Supervision	Supervision	-	Supervision	YES
5007717	27581193	BL	2	performed the maize 56 k chip genotyping|conceived the project	performed the maize 56 k chip genotyping	Performed the experiments	Investigation	YES
5007717	27581193	BL	2	performed the maize 56 k chip genotyping|conceived the project	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5007717	27581193	DL	2	participated in sample collection	participated in sample collection	Performed the experiments	Investigation	YES
5007717	27581193	GP	2	conceived the project	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5007717	27581193	HZ	2	participated in project design and provided some of the inbred lines	participated in project design and provided some of the inbred lines	Conceived and designed the experiments	Methodology	YES
5007717	27581193	Hai Lan	2	managed the field work and provided pedigree information	managed the field work and provided pedigree information	Performed the experiments	Investigation	YES
5007717	27581193	Hailan Liu	2	supervised manuscript discussion and writing	supervised manuscript discussion and writing	Wrote the paper	Supervision|Writing - Original Draft	YES
5007717	27581193	JJ	2	performed the maize 56 k chip genotyping|helped draft the manuscript	performed the maize 56 k chip genotyping	Performed the experiments	Investigation	YES
5007717	27581193	JJ	2	performed the maize 56 k chip genotyping|helped draft the manuscript	helped draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5007717	27581193	LL	2	managed the field work and provided pedigree information	managed the field work and provided pedigree information	Performed the experiments	Investigation	YES
5007717	27581193	LW	2	participated in sample collection	participated in sample collection	Performed the experiments	Investigation	YES
5007717	27581193	SG	2	supervised manuscript discussion and writing|conceived the project	supervised manuscript discussion and writing	Wrote the paper	Supervision|Writing - Original Draft	YES
5007717	27581193	SG	2	supervised manuscript discussion and writing|conceived the project	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5007717	27581193	XZ	2	performed all bioinformatic analysis, collected samples, and wrote the manuscript	performed all bioinformatic analysis, collected samples, and wrote the manuscript	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5007717	27581193	ZR	2	participated in sample collection	participated in sample collection	Performed the experiments	Investigation	YES
4398422	25875358	GV	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398422	25875358	GV	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398422	25875358	JK	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398422	25875358	JK	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398422	25875358	KJS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398422	25875358	KJS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398422	25875358	KJS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398422	25875358	MJMF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398422	25875358	MJMF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398422	25875358	MJMF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398422	25875358	MJMF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398422	25875358	PWR	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398422	25875358	PWR	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398422	25875358	SKS	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398422	25875358	SKS	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6409573	30717471	F.H.	CRediT	Conceptualization|writing--original draft preparation	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6409573	30717471	F.H.	CRediT	Conceptualization|writing--original draft preparation	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6409573	30717471	L.C.	CRediT	validation	validation	Performed the experiments	Validation	YES
6409573	30717471	L.X.	CRediT	Conceptualization|writing--original draft preparation|writing--review and editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6409573	30717471	L.X.	CRediT	Conceptualization|writing--original draft preparation|writing--review and editing	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6409573	30717471	L.X.	CRediT	Conceptualization|writing--original draft preparation|writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6409573	30717471	S.L.	CRediT	writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6409573	30717471	W.Z.	CRediT	methodology|validation	methodology	Performed the experiments	Methodology	YES
6409573	30717471	W.Z.	CRediT	methodology|validation	validation	Performed the experiments	Validation	YES
6409573	30717471	Y.W.	CRediT	software	software	Contributed reagents/materials/analysis tools	Software	YES
6409573	30717471	Z.X.	CRediT	validation	validation	Performed the experiments	Validation	YES
5437698	28579996	BM	2	designed experiments and wrote the manuscript	designed experiments and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5437698	28579996	CO	2	conducted the lc-ms analysis	conducted the lc-ms analysis	Performed the experiments	Investigation	YES
5437698	28579996	FD	2	conducted almond flower bud sampling and the evaluation of the flower bud development	conducted almond flower bud sampling and the evaluation of the flower bud development	Performed the experiments	Investigation	YES
5437698	28579996	II	2	designed and conducted the main experiments and wrote the manuscript	designed and conducted the main experiments and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5437698	28579996	JD	2	designed and conducted the main experiments and wrote the manuscript|assisted with the sweet cherry experiments	designed and conducted the main experiments and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5437698	28579996	JD	2	designed and conducted the main experiments and wrote the manuscript|assisted with the sweet cherry experiments	assisted with the sweet cherry experiments	Performed the experiments	Investigation	YES
5437698	28579996	MM	2	synthesized most of the reference compounds and contributed to the manuscript	synthesized most of the reference compounds and contributed to the manuscript	Performed the experiments	Investigation	YES
5437698	28579996	MP	2	conducted lc-ms data analysis and contributed to the manuscript	conducted lc-ms data analysis and contributed to the manuscript	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5437698	28579996	OG	2	performed the qrt-pcr experiments and wrote the manuscript	performed the qrt-pcr experiments and wrote the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5437698	28579996	RS-P	2	designed and coordinated experiments, conducted lc-ms data analysis and wrote the manuscript	designed and coordinated experiments, conducted lc-ms data analysis and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Project administration|Writing - Original Draft	YES
5009518	27586129	BH	2	collected and analyzed the data, performed all the experiments|designed the seed-extension strategy	collected and analyzed the data, performed all the experiments	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5009518	27586129	BH	2	collected and analyzed the data, performed all the experiments|designed the seed-extension strategy	designed the seed-extension strategy	Conceived and designed the experiments	-	YES
5009518	27586129	HF	2	reviewed and edited the paper	reviewed and edited the paper	Wrote the paper	Writing - Review & Editing	YES
5009518	27586129	RB	2	initiated this project|designed the seed-extension strategy	initiated this project	Conceived and designed the experiments	Conceptualization	YES
5009518	27586129	RB	2	initiated this project|designed the seed-extension strategy	designed the seed-extension strategy	Conceived and designed the experiments	-	YES
5009518	27586129	SM	2	reviewed and edited the paper	reviewed and edited the paper	Wrote the paper	Writing - Review & Editing	YES
5009518	27586129	Section Methods	2	of the paper	of the paper	-	-	NO
5009518	27586129	TW	2	initiated this project|reviewed and edited the paper	initiated this project	Conceived and designed the experiments	Conceptualization	YES
5009518	27586129	TW	2	initiated this project|reviewed and edited the paper	reviewed and edited the paper	Wrote the paper	Writing - Review & Editing	YES
5009518	27586129	YR	2	initiated this project	initiated this project	Conceived and designed the experiments	Conceptualization	YES
6409574	30781584	G.I.	2	conducted the literature review and wrote the manuscript	conducted the literature review and wrote the manuscript	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
6409574	30781584	G.R.	2	conceived the review|conducted the literature review and wrote the manuscript	conceived the review	Conceived and designed the experiments	Conceptualization	YES
6409574	30781584	G.R.	2	conceived the review|conducted the literature review and wrote the manuscript	conducted the literature review and wrote the manuscript	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
6409574	30781584	M.D.L.	2	conducted the literature review and wrote the manuscript	conducted the literature review and wrote the manuscript	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
6409574	30781584	all the authors	2	critically reviewed the manuscript	critically reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
4398423	25874799	EJA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398423	25874799	EJA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398423	25874799	EJA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398423	25874799	EJA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398423	25874799	LS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398423	25874799	LS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398423	25874799	LS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398423	25874799	LS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398423	25874799	MMT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398423	25874799	MMT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398423	25874799	MMT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398423	25874799	MMT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398423	25874799	SDH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398423	25874799	SDH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398423	25874799	SDH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398423	25874799	SGW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398423	25874799	SGW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398423	25874799	SGW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5437873	28579994	AS	4	The experimental work was done by	The experimental work was done by	Performed the experiments	Investigation	YES
5437873	28579994	HN	4	was written by	was written by	Wrote the paper	Writing - Original Draft	YES
5437873	28579994	JK	4	The germplasm was provided by	The germplasm was provided by	-	-	NO
5437873	28579994	KHMS	4	was edited by	was edited by	Wrote the paper	Writing - Review & Editing	YES
5437873	28579994	KS	4	The experimental work was done by	The experimental work was done by	Performed the experiments	Investigation	YES
5437873	28579994	SK	4	The germplasm was provided by	The germplasm was provided by	-	-	NO
5437873	28579994	SS	4	The germplasm was provided by	The germplasm was provided by	-	-	NO
6409575	30704034	A.F.-D.	CRediT	Methodology	Methodology	Performed the experiments	Methodology	YES
6409575	30704034	C.C.	CRediT	Methodology	Methodology	Performed the experiments	Methodology	YES
6409575	30704034	E.B.	CRediT	Methodology	Methodology	Performed the experiments	Methodology	YES
6409575	30704034	M.L.-L.	CRediT	Methodology|writing-original draft preparation|supervision	Methodology	Performed the experiments	Methodology	YES
6409575	30704034	M.L.-L.	CRediT	Methodology|writing-original draft preparation|supervision	writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
6409575	30704034	M.L.-L.	CRediT	Methodology|writing-original draft preparation|supervision	supervision	-	Supervision	YES
6409575	30704034	M.L.M.	CRediT	Methodology|writing-original draft preparation|supervision|funding acquisition	Methodology	Performed the experiments	Methodology	YES
6409575	30704034	M.L.M.	CRediT	Methodology|writing-original draft preparation|supervision|funding acquisition	writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
6409575	30704034	M.L.M.	CRediT	Methodology|writing-original draft preparation|supervision|funding acquisition	supervision	-	Supervision	YES
6409575	30704034	M.L.M.	CRediT	Methodology|writing-original draft preparation|supervision|funding acquisition	funding acquisition	-	Funding acquisition	YES
6409575	30704034	P.L.-C.	CRediT	writing-original draft preparation|funding acquisition	writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
6409575	30704034	P.L.-C.	CRediT	writing-original draft preparation|funding acquisition	funding acquisition	-	Funding acquisition	YES
5009520	27586503	Both authors	2	have participated study discussion and manuscript preparation	have participated study discussion and manuscript preparation	Wrote the paper	Writing - Original Draft	YES
5009520	27586503	RX	2	conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5009520	27586503	YC	2	designed the methods, performed the experiments and wrote the manuscript	designed the methods, performed the experiments and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
4407398	25949999	Si-Yuan Qin	2	contributed equally to this work	contributed equally to this work	-	-	NO
4407398	25949999	Xiao-Xuan Zhang	2	contributed equally to this work	contributed equally to this work	-	-	NO
4398424	25875897	AR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398424	25875897	AR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398424	25875897	AR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398424	25875897	CG	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398424	25875897	CG	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398424	25875897	FR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398424	25875897	FR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398424	25875897	FR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398424	25875897	FR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398424	25875897	JK	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398424	25875897	PA	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5438964	28588589	DC	2	analyzed data and wrote the manuscript|critically evaluated the manuscript	analyzed data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5438964	28588589	DC	2	analyzed data and wrote the manuscript|critically evaluated the manuscript	critically evaluated the manuscript	-	-	NO
5438964	28588589	DT	2	designed experiments|analyzed data and wrote the manuscript|critically evaluated the manuscript	designed experiments	Conceived and designed the experiments	Methodology	YES
5438964	28588589	DT	2	designed experiments|analyzed data and wrote the manuscript|critically evaluated the manuscript	analyzed data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5438964	28588589	DT	2	designed experiments|analyzed data and wrote the manuscript|critically evaluated the manuscript	critically evaluated the manuscript	-	-	NO
5438964	28588589	JS	2	designed experiments|performed experiments	designed experiments	Conceived and designed the experiments	Methodology	YES
5438964	28588589	JS	2	designed experiments|performed experiments	performed experiments	Performed the experiments	Investigation	YES
5438964	28588589	KV	2	designed experiments|performed experiments|analyzed data and wrote the manuscript	designed experiments	Conceived and designed the experiments	Methodology	YES
5438964	28588589	KV	2	designed experiments|performed experiments|analyzed data and wrote the manuscript	performed experiments	Performed the experiments	Investigation	YES
5438964	28588589	KV	2	designed experiments|performed experiments|analyzed data and wrote the manuscript	analyzed data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5438964	28588589	MM	2	designed experiments	designed experiments	Conceived and designed the experiments	Methodology	YES
5438964	28588589	NU	2	designed experiments|performed experiments|analyzed data and wrote the manuscript	designed experiments	Conceived and designed the experiments	Methodology	YES
5438964	28588589	NU	2	designed experiments|performed experiments|analyzed data and wrote the manuscript	performed experiments	Performed the experiments	Investigation	YES
5438964	28588589	NU	2	designed experiments|performed experiments|analyzed data and wrote the manuscript	analyzed data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5438964	28588589	RM	2	designed experiments|performed experiments|analyzed data and wrote the manuscript	designed experiments	Conceived and designed the experiments	Methodology	YES
5438964	28588589	RM	2	designed experiments|performed experiments|analyzed data and wrote the manuscript	performed experiments	Performed the experiments	Investigation	YES
5438964	28588589	RM	2	designed experiments|performed experiments|analyzed data and wrote the manuscript	analyzed data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5438964	28588589	RR	2	analyzed data and wrote the manuscript	analyzed data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5438964	28588589	SS	2	designed experiments|critically evaluated the manuscript	designed experiments	Conceived and designed the experiments	Methodology	YES
5438964	28588589	SS	2	designed experiments|critically evaluated the manuscript	critically evaluated the manuscript	-	-	NO
5438964	28588589	VK	2	analyzed data and wrote the manuscript	analyzed data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4787313	27014392	C.R.S.	2	all co-authors provided comments on this	all co-authors provided comments on this	-	-	NO
5009525	27585456	AR	2	implemented and ran the qpcr experiment, from the selection of the genes to the lab analysis	implemented and ran the qpcr experiment, from the selection of the genes to the lab analysis	Performed the experiments	Investigation	YES
5009525	27585456	AZ	2	contributed to designing the algorithms and the experiments, writing the manuscript and supervised the project	contributed to designing the algorithms and the experiments, writing the manuscript and supervised the project	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Methodology|Software|Supervision|Writing - Original Draft	YES
5009525	27585456	KB	2	implemented and ran the qpcr experiment, from the selection of the genes to the lab analysis	implemented and ran the qpcr experiment, from the selection of the genes to the lab analysis	Performed the experiments	Investigation	YES
5009525	27585456	KEGG	2	pathway to graph	pathway to graph	-	-	NO
5009525	27585456	MM	2	implemented and ran the qpcr experiment, from the selection of the genes to the lab analysis	implemented and ran the qpcr experiment, from the selection of the genes to the lab analysis	Performed the experiments	Investigation	YES
5009525	27585456	NL	2	provided the data and designed and supervised the qpcr analysis|also wrote part of the manuscript	provided the data and designed and supervised the qpcr analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources|Supervision	YES
5009525	27585456	NL	2	provided the data and designed and supervised the qpcr analysis|also wrote part of the manuscript	also wrote part of the manuscript	Wrote the paper	Writing - Original Draft	YES
5009525	27585456	OG	2	participated in validating the xpathway algorithms	participated in validating the xpathway algorithms	Performed the experiments|Contributed reagents/materials/analysis tools	Software|Validation	YES
5009525	27585456	SS	2	ran the isode to compute transcript differential expression and wrote part of the manuscript	ran the isode to compute transcript differential expression and wrote part of the manuscript	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5009525	27585456	YTT	2	also contributed to designing the algorithms and wrote part of the manuscript	also contributed to designing the algorithms and wrote part of the manuscript	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Software|Writing - Original Draft	YES
4398425	25874552	CH	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398425	25874552	CH	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398425	25874552	CZ	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4398425	25874552	CZ	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398425	25874552	HJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the software used in analysis	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398425	25874552	HJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the software used in analysis	Performed the experiments	Performed the experiments	Investigation	YES
4398425	25874552	HJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the software used in analysis	Analyzed the data	Analyzed the data	Formal analysis	YES
4398425	25874552	HJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the software used in analysis	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398425	25874552	HJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the software used in analysis	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398425	25874552	HJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the software used in analysis	Designed the software used in analysis	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
4398425	25874552	LS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398425	25874552	LS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398425	25874552	TY	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the software used in analysis	Performed the experiments	Performed the experiments	Investigation	YES
4398425	25874552	TY	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the software used in analysis	Analyzed the data	Analyzed the data	Formal analysis	YES
4398425	25874552	TY	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the software used in analysis	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398425	25874552	TY	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the software used in analysis	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398425	25874552	TY	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the software used in analysis	Designed the software used in analysis	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
4398425	25874552	YW	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398425	25874552	YW	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398425	25874552	YW	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398425	25874552	YW	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398425	25874552	ZT	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398425	25874552	ZT	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6409650	30736430	G.M.	CRediT	Conceptualization|resources|writing--review and editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6409650	30736430	G.M.	CRediT	Conceptualization|resources|writing--review and editing	resources	Contributed reagents/materials/analysis tools	Resources	YES
6409650	30736430	G.M.	CRediT	Conceptualization|resources|writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6409650	30736430	I.R.-J.	CRediT	Conceptualization|methodology|formal analysis|investigation|visualization|writing--original draft|writing--review and editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6409650	30736430	I.R.-J.	CRediT	Conceptualization|methodology|formal analysis|investigation|visualization|writing--original draft|writing--review and editing	methodology	Performed the experiments	Methodology	YES
6409650	30736430	I.R.-J.	CRediT	Conceptualization|methodology|formal analysis|investigation|visualization|writing--original draft|writing--review and editing	formal analysis	Analyzed the data	Formal analysis	YES
6409650	30736430	I.R.-J.	CRediT	Conceptualization|methodology|formal analysis|investigation|visualization|writing--original draft|writing--review and editing	investigation	Performed the experiments	Investigation	YES
6409650	30736430	I.R.-J.	CRediT	Conceptualization|methodology|formal analysis|investigation|visualization|writing--original draft|writing--review and editing	visualization	Analyzed the data	Visualization	YES
6409650	30736430	I.R.-J.	CRediT	Conceptualization|methodology|formal analysis|investigation|visualization|writing--original draft|writing--review and editing	writing--original draft	Wrote the paper	Writing - Original Draft	YES
6409650	30736430	I.R.-J.	CRediT	Conceptualization|methodology|formal analysis|investigation|visualization|writing--original draft|writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6409650	30736430	J.T.	CRediT	Conceptualization|resources|supervision|writing--review and editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6409650	30736430	J.T.	CRediT	Conceptualization|resources|supervision|writing--review and editing	resources	Contributed reagents/materials/analysis tools	Resources	YES
6409650	30736430	J.T.	CRediT	Conceptualization|resources|supervision|writing--review and editing	supervision	-	Supervision	YES
6409650	30736430	J.T.	CRediT	Conceptualization|resources|supervision|writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6409650	30736430	L.C.	CRediT	Conceptualization|methodology|project administration|supervision|writing--original draft|writing--review and editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6409650	30736430	L.C.	CRediT	Conceptualization|methodology|project administration|supervision|writing--original draft|writing--review and editing	methodology	Performed the experiments	Methodology	YES
6409650	30736430	L.C.	CRediT	Conceptualization|methodology|project administration|supervision|writing--original draft|writing--review and editing	project administration	-	Project administration	YES
6409650	30736430	L.C.	CRediT	Conceptualization|methodology|project administration|supervision|writing--original draft|writing--review and editing	supervision	-	Supervision	YES
6409650	30736430	L.C.	CRediT	Conceptualization|methodology|project administration|supervision|writing--original draft|writing--review and editing	writing--original draft	Wrote the paper	Writing - Original Draft	YES
6409650	30736430	L.C.	CRediT	Conceptualization|methodology|project administration|supervision|writing--original draft|writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6409650	30736430	M.K.	CRediT	investigation|writing--review and editing	investigation	Performed the experiments	Investigation	YES
6409650	30736430	M.K.	CRediT	investigation|writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6409650	30736430	M.T.	CRediT	Conceptualization|methodology|project administration|supervision|writing--review and editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6409650	30736430	M.T.	CRediT	Conceptualization|methodology|project administration|supervision|writing--review and editing	methodology	Performed the experiments	Methodology	YES
6409650	30736430	M.T.	CRediT	Conceptualization|methodology|project administration|supervision|writing--review and editing	project administration	-	Project administration	YES
6409650	30736430	M.T.	CRediT	Conceptualization|methodology|project administration|supervision|writing--review and editing	supervision	-	Supervision	YES
6409650	30736430	M.T.	CRediT	Conceptualization|methodology|project administration|supervision|writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6409650	30736430	N.E.	CRediT	project administration|resources|writing--review and editing	project administration	-	Project administration	YES
6409650	30736430	N.E.	CRediT	project administration|resources|writing--review and editing	resources	Contributed reagents/materials/analysis tools	Resources	YES
6409650	30736430	N.E.	CRediT	project administration|resources|writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6409650	30736430	N.W.	CRediT	Conceptualization|investigation|resources|visualization|writing--review and editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6409650	30736430	N.W.	CRediT	Conceptualization|investigation|resources|visualization|writing--review and editing	investigation	Performed the experiments	Investigation	YES
6409650	30736430	N.W.	CRediT	Conceptualization|investigation|resources|visualization|writing--review and editing	resources	Contributed reagents/materials/analysis tools	Resources	YES
6409650	30736430	N.W.	CRediT	Conceptualization|investigation|resources|visualization|writing--review and editing	visualization	Analyzed the data	Visualization	YES
6409650	30736430	N.W.	CRediT	Conceptualization|investigation|resources|visualization|writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6409650	30736430	P.E.	CRediT	supervision|writing--review and editing	supervision	-	Supervision	YES
6409650	30736430	P.E.	CRediT	supervision|writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6409650	30736430	S.V.	CRediT	investigation|writing--review and editing	investigation	Performed the experiments	Investigation	YES
6409650	30736430	S.V.	CRediT	investigation|writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6409650	30736430	S.d.J.	CRediT	investigation|visualization|writing--review and editing	investigation	Performed the experiments	Investigation	YES
6409650	30736430	S.d.J.	CRediT	investigation|visualization|writing--review and editing	visualization	Analyzed the data	Visualization	YES
6409650	30736430	S.d.J.	CRediT	investigation|visualization|writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
5438981	28588587	HDKD	2	carried out the genomic experiment and drafted the manuscript|participated in the design of the study and revised the manuscript	carried out the genomic experiment and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5438981	28588587	HDKD	2	carried out the genomic experiment and drafted the manuscript|participated in the design of the study and revised the manuscript	participated in the design of the study and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5438981	28588587	J-HK	2	participated in the design of the study and revised the manuscript	participated in the design of the study and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5009526	27585810	KZ	2	performed algorithm design and implementations|analyzed the data and wrote the manuscript	performed algorithm design and implementations	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5009526	27585810	KZ	2	performed algorithm design and implementations|analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5009526	27585810	RMW	2	analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5009526	27585810	YL	2	provided the experimental data|analyzed the data and wrote the manuscript	provided the experimental data	Contributed reagents/materials/analysis tools	Resources	YES
5009526	27585810	YL	2	provided the experimental data|analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4398426	25875015	JI	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4398426	25875015	JL	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4398426	25875015	JL	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4398426	25875015	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398426	25875015	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398426	25875015	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398426	25875015	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398426	25875015	RS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398426	25875015	RS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398426	25875015	RS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6409699	30717104	A.B.G.	CRediT	Supervision|Funding acquisition	Supervision	-	Supervision	YES
6409699	30717104	A.B.G.	CRediT	Supervision|Funding acquisition	Funding acquisition	-	Funding acquisition	YES
6409699	30717104	A.P.	CRediT	Conceptualization|Data curation|Writing--review & editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6409699	30717104	A.P.	CRediT	Conceptualization|Data curation|Writing--review & editing	Data curation	Analyzed the data	Data curation	YES
6409699	30717104	A.P.	CRediT	Conceptualization|Data curation|Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6409699	30717104	A.T.B.	CRediT	Supervision|Funding acquisition	Supervision	-	Supervision	YES
6409699	30717104	A.T.B.	CRediT	Supervision|Funding acquisition	Funding acquisition	-	Funding acquisition	YES
6409699	30717104	E.C.	CRediT	Methodology	Methodology	Performed the experiments	Methodology	YES
6409699	30717104	F.C.	CRediT	Conceptualization|Data curation|Writing--review & editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6409699	30717104	F.C.	CRediT	Conceptualization|Data curation|Writing--review & editing	Data curation	Analyzed the data	Data curation	YES
6409699	30717104	F.C.	CRediT	Conceptualization|Data curation|Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6409699	30717104	G.A.	CRediT	Conceptualization	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6409699	30717104	G.F.	CRediT	Supervision|Funding acquisition	Supervision	-	Supervision	YES
6409699	30717104	G.F.	CRediT	Supervision|Funding acquisition	Funding acquisition	-	Funding acquisition	YES
6409699	30717104	L.C.	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
6409699	30717104	L.P.	CRediT	Methodology|Investigation	Methodology	Performed the experiments	Methodology	YES
6409699	30717104	L.P.	CRediT	Methodology|Investigation	Investigation	Performed the experiments	Investigation	YES
6409699	30717104	M.C.D.	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
6409699	30717104	R.P.	CRediT	Supervision	Supervision	-	Supervision	YES
6409699	30717104	S.F.	CRediT	Methodology|Formal analysis|Investigation	Methodology	Performed the experiments	Methodology	YES
6409699	30717104	S.F.	CRediT	Methodology|Formal analysis|Investigation	Formal analysis	Analyzed the data	Formal analysis	YES
6409699	30717104	S.F.	CRediT	Methodology|Formal analysis|Investigation	Investigation	Performed the experiments	Investigation	YES
6409699	30717104	V.C.	CRediT	Methodology|Formal analysis|Investigation|Data curation	Methodology	Performed the experiments	Methodology	YES
6409699	30717104	V.C.	CRediT	Methodology|Formal analysis|Investigation|Data curation	Formal analysis	Analyzed the data	Formal analysis	YES
6409699	30717104	V.C.	CRediT	Methodology|Formal analysis|Investigation|Data curation	Investigation	Performed the experiments	Investigation	YES
6409699	30717104	V.C.	CRediT	Methodology|Formal analysis|Investigation|Data curation	Data curation	Analyzed the data	Data curation	YES
6409699	30717104	V.S.	CRediT	Methodology	Methodology	Performed the experiments	Methodology	YES
3499928	22713354	All authors	2	have given final approval of the version to be published	have given final approval of the version to be published	-	-	NO
3499928	22713354	MM	2	conceptualized the study, did the data collection and analysis and wrote the first draft of the manuscript	conceptualized the study, did the data collection and analysis and wrote the first draft of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
3499928	22713354	SM	2	contributed towards the conceptualization of the study, participated in the analysis and interpretation of the findings and writing of the manuscript	contributed towards the conceptualization of the study, participated in the analysis and interpretation of the findings and writing of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
3499928	22713354	VB	2	contributed towards the conceptualization of the study, participated in the analysis and interpretation of the findings and writing of the manuscript	contributed towards the conceptualization of the study, participated in the analysis and interpretation of the findings and writing of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
4320865	25685142	Jie Shen	2	helped with ct scan for all the patients	helped with ct scan for all the patients	-	-	NO
4398427	25874569	CD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398427	25874569	CD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398427	25874569	CD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398427	25874569	JA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398427	25874569	JA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398427	25874569	JA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398427	25874569	JJG	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398427	25874569	JJG	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398427	25874569	LY	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398427	25874569	RBH	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398427	25874569	RBH	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398427	25874569	RS	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398427	25874569	RS	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398427	25874569	ZP	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5438988	28588598	AM	2	contributed in the breeding conception of the work, edited, critically reviewed, and gave final approval of the version of the manuscript	contributed in the breeding conception of the work, edited, critically reviewed, and gave final approval of the version of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Review & Editing	YES
5438988	28588598	DA	2	also reviewed the manuscript	also reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5438988	28588598	GEBV	2	selection as well as review of the manuscript	selection as well as review of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5438988	28588598	JO	2	also reviewed the manuscript	also reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5438988	28588598	NU	2	contributed in the genotypic selection of the work	contributed in the genotypic selection of the work	Performed the experiments	Investigation	YES
5438988	28588598	RA	2	analyzed, interpreted the data, and wrote the manuscript	analyzed, interpreted the data, and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5438988	28588598	SA	2	also reviewed the manuscript	also reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5438988	28588598	SH	2	designed and optimized the experiment	designed and optimized the experiment	Conceived and designed the experiments	Methodology	YES
5438988	28588598	SM	2	also reviewed the manuscript	also reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
3500456	23199798	All	2	other co-authors contributed intellectually to the content, gave input and approved the final version	other co-authors contributed intellectually to the content, gave input and approved the final version	-	-	NO
3500456	23199798	MFC	2	conceived and drafted the manuscript	conceived and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
6409701	30691070	C.-R.Y.	CRediT	Conceptualization|Funding acquisition	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6409701	30691070	C.-R.Y.	CRediT	Conceptualization|Funding acquisition	Funding acquisition	-	Funding acquisition	YES
6409701	30691070	C.-S.W.	CRediT	Conceptualization|Data curation|Funding acquisition|Writing--review & editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6409701	30691070	C.-S.W.	CRediT	Conceptualization|Data curation|Funding acquisition|Writing--review & editing	Data curation	Analyzed the data	Data curation	YES
6409701	30691070	C.-S.W.	CRediT	Conceptualization|Data curation|Funding acquisition|Writing--review & editing	Funding acquisition	-	Funding acquisition	YES
6409701	30691070	C.-S.W.	CRediT	Conceptualization|Data curation|Funding acquisition|Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6409701	30691070	C.-Y.Z.	CRediT	Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6409701	30691070	L.-Y.H.	CRediT	Conceptualization|Data curation|Formal analysis|Methodology|Writing--original draft	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6409701	30691070	L.-Y.H.	CRediT	Conceptualization|Data curation|Formal analysis|Methodology|Writing--original draft	Data curation	Analyzed the data	Data curation	YES
6409701	30691070	L.-Y.H.	CRediT	Conceptualization|Data curation|Formal analysis|Methodology|Writing--original draft	Formal analysis	Analyzed the data	Formal analysis	YES
6409701	30691070	L.-Y.H.	CRediT	Conceptualization|Data curation|Formal analysis|Methodology|Writing--original draft	Methodology	Performed the experiments	Methodology	YES
6409701	30691070	L.-Y.H.	CRediT	Conceptualization|Data curation|Formal analysis|Methodology|Writing--original draft	Writing--original draft	Wrote the paper	Writing - Original Draft	YES
6409701	30691070	Y.-L.W.	CRediT	Conceptualization|Writing--review & editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6409701	30691070	Y.-L.W.	CRediT	Conceptualization|Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
4398428	25874711	RE	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398428	25874711	RE	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398428	25874711	RE	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398428	25874711	RE	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5009542	27590805	JGG	2	designed the study, performed the bioinformatics analysis, and wrote the manuscript	designed the study, performed the bioinformatics analysis, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5009542	27590805	JLS	2	designed the study, performed the bioinformatics analysis, and wrote the manuscript	designed the study, performed the bioinformatics analysis, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5009542	27590805	JRP	2	contributed data	contributed data	Contributed reagents/materials/analysis tools	Resources	YES
6409705	30736357	Athanasios Mantas	2	performed dissolution experiments in biorelevant media	performed dissolution experiments in biorelevant media	Performed the experiments	Investigation	YES
6409705	30736357	I.L.	2	performed the pk data analysis	performed the pk data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6409705	30736357	V.L.	2	performed most of the solid state characterizations	performed most of the solid state characterizations	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5438989	28588597	QISH	2	wrote the first draft of the manuscript and participated in later revisions|participated in the writing and revision of the manuscript	wrote the first draft of the manuscript and participated in later revisions	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5438989	28588597	QISH	2	wrote the first draft of the manuscript and participated in later revisions|participated in the writing and revision of the manuscript	participated in the writing and revision of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5781221	23331969	AB	PLoS5	Agree with the manuscripts results and conclusions|Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript|Reviewed and edited versions of the manuscript	Agree with the manuscripts results and conclusions	-	-	NO
5781221	23331969	AB	PLoS5	Agree with the manuscripts results and conclusions|Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript|Reviewed and edited versions of the manuscript	Agree with the manuscripts results and conclusions	-	-	NO
5781221	23331969	AB	PLoS5	Agree with the manuscripts results and conclusions|Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript|Reviewed and edited versions of the manuscript	Reviewed and edited versions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5781221	23331969	AB	PLoS5	Agree with the manuscripts results and conclusions|Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript|Reviewed and edited versions of the manuscript	Reviewed and edited versions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5781221	23331969	ACM	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Agree with the manuscripts results and conclusions	-	-	NO
5781221	23331969	ACM	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Reviewed and edited versions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5781221	23331969	AK	PLoS5	Analyzed the data|Agree with the manuscripts results and conclusions|Wrote the first draft of the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5781221	23331969	AK	PLoS5	Analyzed the data|Agree with the manuscripts results and conclusions|Wrote the first draft of the paper	Agree with the manuscripts results and conclusions	-	-	NO
5781221	23331969	AK	PLoS5	Analyzed the data|Agree with the manuscripts results and conclusions|Wrote the first draft of the paper	Wrote the first draft of the paper	Wrote the paper	Writing - Original Draft	YES
5781221	23331969	AL	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Agree with the manuscripts results and conclusions	-	-	NO
5781221	23331969	AL	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Reviewed and edited versions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5781221	23331969	AMF	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Agree with the manuscripts results and conclusions	-	-	NO
5781221	23331969	AMF	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Reviewed and edited versions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5781221	23331969	AS	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Agree with the manuscripts results and conclusions	-	-	NO
5781221	23331969	AS	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Reviewed and edited versions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5781221	23331969	AWM	PLoS5	Conceived and designed the experiments|Analyzed the data|Agree with the manuscripts results and conclusions|Wrote the first draft of the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5781221	23331969	AWM	PLoS5	Conceived and designed the experiments|Analyzed the data|Agree with the manuscripts results and conclusions|Wrote the first draft of the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5781221	23331969	AWM	PLoS5	Conceived and designed the experiments|Analyzed the data|Agree with the manuscripts results and conclusions|Wrote the first draft of the paper	Agree with the manuscripts results and conclusions	-	-	NO
5781221	23331969	AWM	PLoS5	Conceived and designed the experiments|Analyzed the data|Agree with the manuscripts results and conclusions|Wrote the first draft of the paper	Wrote the first draft of the paper	Wrote the paper	Writing - Original Draft	YES
5781221	23331969	BVT	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Agree with the manuscripts results and conclusions	-	-	NO
5781221	23331969	BVT	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Reviewed and edited versions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5781221	23331969	CAD	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Agree with the manuscripts results and conclusions	-	-	NO
5781221	23331969	CAD	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Reviewed and edited versions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5781221	23331969	CMC	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Agree with the manuscripts results and conclusions	-	-	NO
5781221	23331969	CMC	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Reviewed and edited versions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5781221	23331969	CR	PLoS5	Agree with the manuscripts results and conclusions|Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript|Reviewed and edited versions of the manuscript	Agree with the manuscripts results and conclusions	-	-	NO
5781221	23331969	CR	PLoS5	Agree with the manuscripts results and conclusions|Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript|Reviewed and edited versions of the manuscript	Agree with the manuscripts results and conclusions	-	-	NO
5781221	23331969	CR	PLoS5	Agree with the manuscripts results and conclusions|Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript|Reviewed and edited versions of the manuscript	Reviewed and edited versions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5781221	23331969	CR	PLoS5	Agree with the manuscripts results and conclusions|Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript|Reviewed and edited versions of the manuscript	Reviewed and edited versions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5781221	23331969	CX	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Agree with the manuscripts results and conclusions	-	-	NO
5781221	23331969	CX	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Reviewed and edited versions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5781221	23331969	CYC	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Agree with the manuscripts results and conclusions	-	-	NO
5781221	23331969	CYC	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Reviewed and edited versions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5781221	23331969	DB	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Agree with the manuscripts results and conclusions	-	-	NO
5781221	23331969	DB	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Reviewed and edited versions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5781221	23331969	DLB	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Agree with the manuscripts results and conclusions	-	-	NO
5781221	23331969	DLB	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Reviewed and edited versions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5781221	23331969	DS	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Agree with the manuscripts results and conclusions	-	-	NO
5781221	23331969	DS	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Reviewed and edited versions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5781221	23331969	EM	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Agree with the manuscripts results and conclusions	-	-	NO
5781221	23331969	EM	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Reviewed and edited versions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5781221	23331969	FB	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Agree with the manuscripts results and conclusions	-	-	NO
5781221	23331969	FB	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Reviewed and edited versions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5781221	23331969	GD	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Agree with the manuscripts results and conclusions	-	-	NO
5781221	23331969	GD	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Reviewed and edited versions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5781221	23331969	GLG	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Agree with the manuscripts results and conclusions	-	-	NO
5781221	23331969	GLG	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Reviewed and edited versions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5781221	23331969	HCM	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Agree with the manuscripts results and conclusions	-	-	NO
5781221	23331969	HCM	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Reviewed and edited versions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5781221	23331969	IJ	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Agree with the manuscripts results and conclusions	-	-	NO
5781221	23331969	IJ	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Reviewed and edited versions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5781221	23331969	JC	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Agree with the manuscripts results and conclusions	-	-	NO
5781221	23331969	JC	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Reviewed and edited versions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5781221	23331969	JMK	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Agree with the manuscripts results and conclusions	-	-	NO
5781221	23331969	JMK	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Reviewed and edited versions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5781221	23331969	JMV	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Agree with the manuscripts results and conclusions	-	-	NO
5781221	23331969	JMV	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Reviewed and edited versions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5781221	23331969	JRW	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Agree with the manuscripts results and conclusions	-	-	NO
5781221	23331969	JRW	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Reviewed and edited versions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5781221	23331969	JTW	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Agree with the manuscripts results and conclusions	-	-	NO
5781221	23331969	JTW	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Reviewed and edited versions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5781221	23331969	KD	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Agree with the manuscripts results and conclusions	-	-	NO
5781221	23331969	KD	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Reviewed and edited versions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5781221	23331969	KIH	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Agree with the manuscripts results and conclusions	-	-	NO
5781221	23331969	KIH	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Reviewed and edited versions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5781221	23331969	KW	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Agree with the manuscripts results and conclusions	-	-	NO
5781221	23331969	KW	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Reviewed and edited versions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5781221	23331969	LR	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Agree with the manuscripts results and conclusions	-	-	NO
5781221	23331969	LR	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Reviewed and edited versions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5781221	23331969	MC	PLoS5	Agree with the manuscripts results and conclusions|Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript|Reviewed and edited versions of the manuscript	Agree with the manuscripts results and conclusions	-	-	NO
5781221	23331969	MC	PLoS5	Agree with the manuscripts results and conclusions|Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript|Reviewed and edited versions of the manuscript	Agree with the manuscripts results and conclusions	-	-	NO
5781221	23331969	MC	PLoS5	Agree with the manuscripts results and conclusions|Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript|Reviewed and edited versions of the manuscript	Reviewed and edited versions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5781221	23331969	MC	PLoS5	Agree with the manuscripts results and conclusions|Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript|Reviewed and edited versions of the manuscript	Reviewed and edited versions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5781221	23331969	MDVK	PLoS5	Conceived and designed the experiments|Analyzed the data|Agree with the manuscripts results and conclusions|Wrote the first draft of the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5781221	23331969	MDVK	PLoS5	Conceived and designed the experiments|Analyzed the data|Agree with the manuscripts results and conclusions|Wrote the first draft of the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5781221	23331969	MDVK	PLoS5	Conceived and designed the experiments|Analyzed the data|Agree with the manuscripts results and conclusions|Wrote the first draft of the paper	Agree with the manuscripts results and conclusions	-	-	NO
5781221	23331969	MDVK	PLoS5	Conceived and designed the experiments|Analyzed the data|Agree with the manuscripts results and conclusions|Wrote the first draft of the paper	Wrote the first draft of the paper	Wrote the paper	Writing - Original Draft	YES
5781221	23331969	MM	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Agree with the manuscripts results and conclusions	-	-	NO
5781221	23331969	MM	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Reviewed and edited versions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5781221	23331969	MSC	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Agree with the manuscripts results and conclusions	-	-	NO
5781221	23331969	MSC	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Reviewed and edited versions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5781221	23331969	MT	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Agree with the manuscripts results and conclusions	-	-	NO
5781221	23331969	MT	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Reviewed and edited versions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5781221	23331969	MvB	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Agree with the manuscripts results and conclusions	-	-	NO
5781221	23331969	MvB	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Reviewed and edited versions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5781221	23331969	NC	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Agree with the manuscripts results and conclusions	-	-	NO
5781221	23331969	NC	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Reviewed and edited versions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5781221	23331969	NI	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Agree with the manuscripts results and conclusions	-	-	NO
5781221	23331969	NI	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Reviewed and edited versions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5781221	23331969	NJ	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Agree with the manuscripts results and conclusions	-	-	NO
5781221	23331969	NJ	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Reviewed and edited versions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5781221	23331969	NMF	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Agree with the manuscripts results and conclusions	-	-	NO
5781221	23331969	NMF	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Reviewed and edited versions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5781221	23331969	OH	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Agree with the manuscripts results and conclusions	-	-	NO
5781221	23331969	OH	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Reviewed and edited versions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5781221	23331969	PH	PLoS5	Agree with the manuscripts results and conclusions|Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript|Reviewed and edited versions of the manuscript	Agree with the manuscripts results and conclusions	-	-	NO
5781221	23331969	PH	PLoS5	Agree with the manuscripts results and conclusions|Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript|Reviewed and edited versions of the manuscript	Agree with the manuscripts results and conclusions	-	-	NO
5781221	23331969	PH	PLoS5	Agree with the manuscripts results and conclusions|Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript|Reviewed and edited versions of the manuscript	Reviewed and edited versions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5781221	23331969	PH	PLoS5	Agree with the manuscripts results and conclusions|Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript|Reviewed and edited versions of the manuscript	Reviewed and edited versions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5781221	23331969	QSH	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Agree with the manuscripts results and conclusions	-	-	NO
5781221	23331969	QSH	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Reviewed and edited versions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5781221	23331969	RA	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Agree with the manuscripts results and conclusions	-	-	NO
5781221	23331969	RA	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Reviewed and edited versions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5781221	23331969	SD	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Agree with the manuscripts results and conclusions	-	-	NO
5781221	23331969	SD	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Reviewed and edited versions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5781221	23331969	SH	PLoS5	Conceived and designed the experiments|Analyzed the data|Agree with the manuscripts results and conclusions|Wrote the first draft of the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5781221	23331969	SH	PLoS5	Conceived and designed the experiments|Analyzed the data|Agree with the manuscripts results and conclusions|Wrote the first draft of the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5781221	23331969	SH	PLoS5	Conceived and designed the experiments|Analyzed the data|Agree with the manuscripts results and conclusions|Wrote the first draft of the paper	Agree with the manuscripts results and conclusions	-	-	NO
5781221	23331969	SH	PLoS5	Conceived and designed the experiments|Analyzed the data|Agree with the manuscripts results and conclusions|Wrote the first draft of the paper	Wrote the first draft of the paper	Wrote the paper	Writing - Original Draft	YES
5781221	23331969	SHP	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Agree with the manuscripts results and conclusions	-	-	NO
5781221	23331969	SHP	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Reviewed and edited versions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5781221	23331969	SR	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Agree with the manuscripts results and conclusions	-	-	NO
5781221	23331969	SR	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Reviewed and edited versions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5781221	23331969	SS	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Agree with the manuscripts results and conclusions	-	-	NO
5781221	23331969	SS	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Reviewed and edited versions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5781221	23331969	SZ	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Agree with the manuscripts results and conclusions	-	-	NO
5781221	23331969	SZ	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Reviewed and edited versions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5781221	23331969	TMR	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Agree with the manuscripts results and conclusions	-	-	NO
5781221	23331969	TMR	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Reviewed and edited versions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5781221	23331969	WH	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Agree with the manuscripts results and conclusions	-	-	NO
5781221	23331969	WH	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Reviewed and edited versions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5781221	23331969	XdL	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Agree with the manuscripts results and conclusions	-	-	NO
5781221	23331969	XdL	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Reviewed and edited versions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5781221	23331969	YK	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Agree with the manuscripts results and conclusions	-	-	NO
5781221	23331969	YK	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Reviewed and edited versions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5781221	23331969	YS	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Agree with the manuscripts results and conclusions	-	-	NO
5781221	23331969	YS	PLoS5	Agree with the manuscripts results and conclusions|Reviewed and edited versions of the manuscript	Reviewed and edited versions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4398429	25875790	CC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398429	25875790	CC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398429	25875790	CC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398429	25875790	CC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398429	25875790	CC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398429	25875790	DK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398429	25875790	DK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398429	25875790	DK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398429	25875790	DK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398429	25875790	DK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398429	25875790	KM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398429	25875790	KM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398429	25875790	KM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398429	25875790	KM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398429	25875790	KM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5009557	27585926	BR	2	sequenced and performed data analysis on the bean magic population|wrote the manuscript	sequenced and performed data analysis on the bean magic population	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5009557	27585926	BR	2	sequenced and performed data analysis on the bean magic population|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5009557	27585926	CP	2	contributed software development|performed analysis on the cassava f1 populations|wrote the manuscript	contributed software development	Contributed reagents/materials/analysis tools	Software	YES
5009557	27585926	CP	2	contributed software development|performed analysis on the cassava f1 populations|wrote the manuscript	performed analysis on the cassava f1 populations	Performed the experiments	Investigation	YES
5009557	27585926	CP	2	contributed software development|performed analysis on the cassava f1 populations|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5009557	27585926	DFC	2	contributed software development|wrote the manuscript	contributed software development	Contributed reagents/materials/analysis tools	Software	YES
5009557	27585926	DFC	2	contributed software development|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5009557	27585926	JCQ	2	contributed software development	contributed software development	Contributed reagents/materials/analysis tools	Software	YES
5009557	27585926	JD	2	conceived the study|contributed software development|wrote the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5009557	27585926	JD	2	conceived the study|contributed software development|wrote the manuscript	contributed software development	Contributed reagents/materials/analysis tools	Software	YES
5009557	27585926	JD	2	conceived the study|contributed software development|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5009557	27585926	JDL	2	sequenced and performed data analysis on the bean magic population	sequenced and performed data analysis on the bean magic population	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5009557	27585926	JFD	2	contributed software development|performed analysis on the cassava f1 populations|wrote the manuscript	contributed software development	Contributed reagents/materials/analysis tools	Software	YES
5009557	27585926	JFD	2	contributed software development|performed analysis on the cassava f1 populations|wrote the manuscript	performed analysis on the cassava f1 populations	Performed the experiments	Investigation	YES
5009557	27585926	JFD	2	contributed software development|performed analysis on the cassava f1 populations|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5009557	27585926	PI	2	sequenced and performed data analysis on the bean magic population	sequenced and performed data analysis on the bean magic population	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6409706	30744102	D.B.	CRediT	Conceptualization|investigation|writing--original draft preparation|writing--review and editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6409706	30744102	D.B.	CRediT	Conceptualization|investigation|writing--original draft preparation|writing--review and editing	investigation	Performed the experiments	Investigation	YES
6409706	30744102	D.B.	CRediT	Conceptualization|investigation|writing--original draft preparation|writing--review and editing	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6409706	30744102	D.B.	CRediT	Conceptualization|investigation|writing--original draft preparation|writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6409706	30744102	F.L.	CRediT	investigation	investigation	Performed the experiments	Investigation	YES
6409706	30744102	O.B.	CRediT	Conceptualization|writing--review and editing|funding acquisition	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6409706	30744102	O.B.	CRediT	Conceptualization|writing--review and editing|funding acquisition	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6409706	30744102	O.B.	CRediT	Conceptualization|writing--review and editing|funding acquisition	funding acquisition	-	Funding acquisition	YES
6409706	30744102	S.J.	CRediT	investigation	investigation	Performed the experiments	Investigation	YES
6409706	30744102	T.G.	CRediT	writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
5438991	28588599	ABe	2	contributed in field design and implementation|provided materials and laboratory equipment	contributed in field design and implementation	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5438991	28588599	ABe	2	contributed in field design and implementation|provided materials and laboratory equipment	provided materials and laboratory equipment	Contributed reagents/materials/analysis tools	Resources	YES
5438991	28588599	ABo	2	provided materials and laboratory equipment	provided materials and laboratory equipment	Contributed reagents/materials/analysis tools	Resources	YES
5438991	28588599	BC	2	contributed in field design and implementation|reviewed and discussed the final version of the manuscript	contributed in field design and implementation	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5438991	28588599	BC	2	contributed in field design and implementation|reviewed and discussed the final version of the manuscript	reviewed and discussed the final version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5438991	28588599	CM	2	contributed in field design and implementation|reviewed and discussed the final version of the manuscript	contributed in field design and implementation	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5438991	28588599	CM	2	contributed in field design and implementation|reviewed and discussed the final version of the manuscript	reviewed and discussed the final version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5438991	28588599	CS	2	contributed in field design and implementation|reviewed and discussed the final version of the manuscript	contributed in field design and implementation	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5438991	28588599	CS	2	contributed in field design and implementation|reviewed and discussed the final version of the manuscript	reviewed and discussed the final version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5438991	28588599	DB	2	provided materials and laboratory equipment	provided materials and laboratory equipment	Contributed reagents/materials/analysis tools	Resources	YES
5438991	28588599	DS	2	provided materials and laboratory equipment|reviewed and discussed the final version of the manuscript	provided materials and laboratory equipment	Contributed reagents/materials/analysis tools	Resources	YES
5438991	28588599	DS	2	provided materials and laboratory equipment|reviewed and discussed the final version of the manuscript	reviewed and discussed the final version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5438991	28588599	LF	2	contributed in field design and implementation|provided materials and laboratory equipment	contributed in field design and implementation	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5438991	28588599	LF	2	contributed in field design and implementation|provided materials and laboratory equipment	provided materials and laboratory equipment	Contributed reagents/materials/analysis tools	Resources	YES
5438991	28588599	MF-A	2	designed, implemented the studies, collected and analyzed the data and wrote the manuscript	designed, implemented the studies, collected and analyzed the data and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5438991	28588599	MV	2	provided materials and laboratory equipment|reviewed and discussed the final version of the manuscript	provided materials and laboratory equipment	Contributed reagents/materials/analysis tools	Resources	YES
5438991	28588599	MV	2	provided materials and laboratory equipment|reviewed and discussed the final version of the manuscript	reviewed and discussed the final version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5438991	28588599	PM	2	contributed in field design and implementation|provided materials and laboratory equipment	contributed in field design and implementation	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5438991	28588599	PM	2	contributed in field design and implementation|provided materials and laboratory equipment	provided materials and laboratory equipment	Contributed reagents/materials/analysis tools	Resources	YES
5438991	28588599	SG-L	2	provided materials and laboratory equipment	provided materials and laboratory equipment	Contributed reagents/materials/analysis tools	Resources	YES
5438991	28588599	XR	2	contributed in field design and implementation|provided materials and laboratory equipment|reviewed and discussed the final version of the manuscript	contributed in field design and implementation	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5438991	28588599	XR	2	contributed in field design and implementation|provided materials and laboratory equipment|reviewed and discussed the final version of the manuscript	provided materials and laboratory equipment	Contributed reagents/materials/analysis tools	Resources	YES
5438991	28588599	XR	2	contributed in field design and implementation|provided materials and laboratory equipment|reviewed and discussed the final version of the manuscript	reviewed and discussed the final version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5009558	27585593	LZ	PLoS52	participated in the design of the tool and supervised the project|wrote the paper	participated in the design of the tool and supervised the project	Conceived and designed the experiments	Methodology|Supervision	YES
5009558	27585593	LZ	PLoS52	participated in the design of the tool and supervised the project|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5009558	27585593	MSH	PLoS52	conceived the idea and performed the coding and computational experiments|wrote the paper	conceived the idea and performed the coding and computational experiments	Conceived and designed the experiments|Performed the experiments	Conceptualization|Formal analysis|Investigation	YES
5009558	27585593	MSH	PLoS52	conceived the idea and performed the coding and computational experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6409713	30708963	B.R.C.	2	carried out all experiments and measurements and participated in the draft writing	carried out all experiments and measurements and participated in the draft writing	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6409713	30708963	C.H.K.	2	assisted with the animal experiments	assisted with the animal experiments	Performed the experiments	Investigation	YES
6409713	30708963	D.J.S.	2	carried out all experiments and measurements and participated in the draft writing	carried out all experiments and measurements and participated in the draft writing	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6409713	30708963	Y.W.C.	2	carried out all experiments and measurements and participated in the draft writing|was responsible for paper supervision and writing	carried out all experiments and measurements and participated in the draft writing	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6409713	30708963	Y.W.C.	2	carried out all experiments and measurements and participated in the draft writing|was responsible for paper supervision and writing	was responsible for paper supervision and writing	Wrote the paper	Supervision	YES
4398430	25874930	BL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398430	25874930	CL	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4398430	25874930	DK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398430	25874930	HW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398430	25874930	HW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398430	25874930	SC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398430	25874930	SC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398430	25874930	SC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398430	25874930	SC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398430	25874930	SC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398430	25874930	SL	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4398430	25874930	YS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398430	25874930	YS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5438992	28588591	BG	PLoS5	Interpreted results	Interpreted results	Analyzed the data	Formal analysis	YES
5438992	28588591	MKP	PLoS5	Conceived and designed the experiment|Analyzed data|Interpreted results|Wrote the manuscript	Conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5438992	28588591	MKP	PLoS5	Conceived and designed the experiment|Analyzed data|Interpreted results|Wrote the manuscript	Analyzed data	Analyzed the data	Formal analysis	YES
5438992	28588591	MKP	PLoS5	Conceived and designed the experiment|Analyzed data|Interpreted results|Wrote the manuscript	Interpreted results	Analyzed the data	Formal analysis	YES
5438992	28588591	MKP	PLoS5	Conceived and designed the experiment|Analyzed data|Interpreted results|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5438992	28588591	MKV	PLoS5	Performed the experiments|Analyzed data|Interpreted results|Wrote the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
5438992	28588591	MKV	PLoS5	Performed the experiments|Analyzed data|Interpreted results|Wrote the manuscript	Analyzed data	Analyzed the data	Formal analysis	YES
5438992	28588591	MKV	PLoS5	Performed the experiments|Analyzed data|Interpreted results|Wrote the manuscript	Interpreted results	Analyzed the data	Formal analysis	YES
5438992	28588591	MKV	PLoS5	Performed the experiments|Analyzed data|Interpreted results|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5438992	28588591	MTV	PLoS5	Population development and phenotyping	Population development and phenotyping	Performed the experiments	Investigation	YES
5438992	28588591	PJ	PLoS5	Population development and phenotyping	Population development and phenotyping	Performed the experiments	Investigation	YES
5438992	28588591	RKV	PLoS5	Conceived and designed the experiment|Interpreted results	Conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5438992	28588591	RKV	PLoS5	Conceived and designed the experiment|Interpreted results	Interpreted results	Analyzed the data	Formal analysis	YES
5438992	28588591	SM	PLoS5	Population development and phenotyping	Population development and phenotyping	Performed the experiments	Investigation	YES
5438992	28588591	SN	PLoS5	Population development and phenotyping	Population development and phenotyping	Performed the experiments	Investigation	YES
5438992	28588591	YS	PLoS5	Performed the experiments|Analyzed data|Interpreted results|Wrote the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
5438992	28588591	YS	PLoS5	Performed the experiments|Analyzed data|Interpreted results|Wrote the manuscript	Analyzed data	Analyzed the data	Formal analysis	YES
5438992	28588591	YS	PLoS5	Performed the experiments|Analyzed data|Interpreted results|Wrote the manuscript	Interpreted results	Analyzed the data	Formal analysis	YES
5438992	28588591	YS	PLoS5	Performed the experiments|Analyzed data|Interpreted results|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5009561	27585692	BX	2	designed the experiment, analyzed the data, and wrote the manuscript	designed the experiment, analyzed the data, and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5009561	27585692	BZ	2	designed the experiment, analyzed the data, and wrote the manuscript	designed the experiment, analyzed the data, and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
6409735	30823607	A.P.S.	CRediT	Conceptualization|Methodology|Software|Writing-review & editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6409735	30823607	A.P.S.	CRediT	Conceptualization|Methodology|Software|Writing-review & editing	Methodology	Performed the experiments	Methodology	YES
6409735	30823607	A.P.S.	CRediT	Conceptualization|Methodology|Software|Writing-review & editing	Software	Contributed reagents/materials/analysis tools	Software	YES
6409735	30823607	A.P.S.	CRediT	Conceptualization|Methodology|Software|Writing-review & editing	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6409735	30823607	A.V.	CRediT	Methodology	Methodology	Performed the experiments	Methodology	YES
6409735	30823607	D.K.S.	CRediT	Conceptualization|Software|Resources|Writing-review & editing|Funding acquisition	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6409735	30823607	D.K.S.	CRediT	Conceptualization|Software|Resources|Writing-review & editing|Funding acquisition	Software	Contributed reagents/materials/analysis tools	Software	YES
6409735	30823607	D.K.S.	CRediT	Conceptualization|Software|Resources|Writing-review & editing|Funding acquisition	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6409735	30823607	D.K.S.	CRediT	Conceptualization|Software|Resources|Writing-review & editing|Funding acquisition	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6409735	30823607	D.K.S.	CRediT	Conceptualization|Software|Resources|Writing-review & editing|Funding acquisition	Funding acquisition	-	Funding acquisition	YES
6409735	30823607	G.G.-L.W.	CRediT	Methodology	Methodology	Performed the experiments	Methodology	YES
6409735	30823607	L.G.	CRediT	Methodology	Methodology	Performed the experiments	Methodology	YES
4398431	25876106	JCS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398431	25876106	JCS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398431	25876106	JFD	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398431	25876106	KYC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398431	25876106	LPL	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4398431	25876106	LPL	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4398431	25876106	MHL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398431	25876106	MHL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398431	25876106	MHL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398431	25876106	STL	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398431	25876106	STL	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398431	25876106	YWC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
3504932	23199800	AB	2	participated in data collection and critically revised the manuscript	participated in data collection and critically revised the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
3504932	23199800	BMM	2	participated in data collection and critically revised the manuscript	participated in data collection and critically revised the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
3504932	23199800	CD	2	participated in data collection and critically revised the manuscript	participated in data collection and critically revised the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
3504932	23199800	DN	2	participated in data collection and critically revised the manuscript	participated in data collection and critically revised the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
3504932	23199800	GW	2	conceived the analysis and critically revised the manuscript	conceived the analysis and critically revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
3504932	23199800	HM	2	participated in data collection and critically revised the manuscript	participated in data collection and critically revised the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
3504932	23199800	IA	2	participated in data collection and critically revised the manuscript	participated in data collection and critically revised the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
3504932	23199800	JA	2	participated in data collection and critically revised the manuscript	participated in data collection and critically revised the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
3504932	23199800	JHF	2	oversaw the data collection, data analysis and critically revised the manuscript	oversaw the data collection, data analysis and critically revised the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Supervision|Writing - Review & Editing	YES
3504932	23199800	JN	2	oversaw the data collection, data analysis and critically revised the manuscript	oversaw the data collection, data analysis and critically revised the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Supervision|Writing - Review & Editing	YES
3504932	23199800	KD	2	conducted the data analysis and wrote the first draft of the manuscript	conducted the data analysis and wrote the first draft of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3504932	23199800	LK	2	participated in data collection and critically revised the manuscript	participated in data collection and critically revised the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
3504932	23199800	MK	2	participated in data collection and critically revised the manuscript	participated in data collection and critically revised the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
3504932	23199800	MM	2	participated in data collection and critically revised the manuscript	participated in data collection and critically revised the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
3504932	23199800	TN	2	participated in data collection and critically revised the manuscript	participated in data collection and critically revised the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
3504932	23199800	VM	2	participated in data collection and critically revised the manuscript	participated in data collection and critically revised the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
3504932	23199800	WA	2	participated in data collection and critically revised the manuscript	participated in data collection and critically revised the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5438995	28588596	MD	2	originally formulated the idea and designed the experiments|performed the field experiment and hyperspectral measurements and did the laboratory analyses|performed the statistical analyses and wrote the manuscript	originally formulated the idea and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5438995	28588596	MD	2	originally formulated the idea and designed the experiments|performed the field experiment and hyperspectral measurements and did the laboratory analyses|performed the statistical analyses and wrote the manuscript	performed the field experiment and hyperspectral measurements and did the laboratory analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5438995	28588596	MD	2	originally formulated the idea and designed the experiments|performed the field experiment and hyperspectral measurements and did the laboratory analyses|performed the statistical analyses and wrote the manuscript	performed the statistical analyses and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5438995	28588596	MR	2	provided editorial support and advice	provided editorial support and advice	Wrote the paper	Writing - Review & Editing	YES
5438995	28588596	SW	2	originally formulated the idea and designed the experiments|performed the statistical analyses and wrote the manuscript	originally formulated the idea and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5438995	28588596	SW	2	originally formulated the idea and designed the experiments|performed the statistical analyses and wrote the manuscript	performed the statistical analyses and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5438995	28588596	WZ	2	performed the field experiment and hyperspectral measurements and did the laboratory analyses	performed the field experiment and hyperspectral measurements and did the laboratory analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5438995	28588596	ZS	2	provided editorial support and advice	provided editorial support and advice	Wrote the paper	Writing - Review & Editing	YES
4398432	25874764	AD	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote matlab scripts for tracking algorithm	Performed the experiments	Performed the experiments	Investigation	YES
4398432	25874764	AD	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote matlab scripts for tracking algorithm	Analyzed the data	Analyzed the data	Formal analysis	YES
4398432	25874764	AD	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote matlab scripts for tracking algorithm	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398432	25874764	AD	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote matlab scripts for tracking algorithm	Wrote matlab scripts for tracking algorithm	Contributed reagents/materials/analysis tools|Wrote the paper	Software|Writing - Original Draft	YES
4398432	25874764	AP	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Wrote matlab scripts for tracking algorithm	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398432	25874764	AP	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Wrote matlab scripts for tracking algorithm	Performed the experiments	Performed the experiments	Investigation	YES
4398432	25874764	AP	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Wrote matlab scripts for tracking algorithm	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398432	25874764	AP	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Wrote matlab scripts for tracking algorithm	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398432	25874764	AP	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Wrote matlab scripts for tracking algorithm	Wrote matlab scripts for tracking algorithm	Contributed reagents/materials/analysis tools|Wrote the paper	Software|Writing - Original Draft	YES
4398432	25874764	DG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Wrote matlab scripts for tracking algorithm	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398432	25874764	DG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Wrote matlab scripts for tracking algorithm	Performed the experiments	Performed the experiments	Investigation	YES
4398432	25874764	DG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Wrote matlab scripts for tracking algorithm	Analyzed the data	Analyzed the data	Formal analysis	YES
4398432	25874764	DG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Wrote matlab scripts for tracking algorithm	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398432	25874764	DG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Wrote matlab scripts for tracking algorithm	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398432	25874764	DG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Wrote matlab scripts for tracking algorithm	Wrote matlab scripts for tracking algorithm	Contributed reagents/materials/analysis tools|Wrote the paper	Software|Writing - Original Draft	YES
4398432	25874764	PG	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398432	25874764	PG	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398432	25874764	PG	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398432	25874764	PG	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3510650	23199801	ADM	2	were in charge of the patients medical follow-up	were in charge of the patients medical follow-up	-	-	NO
3510650	23199801	AMO	2	performed the virological analyses	performed the virological analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3510650	23199801	CB	2	performed the virological analyses	performed the virological analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3510650	23199801	CV	2	contributed to the data collection	contributed to the data collection	Performed the experiments	Investigation	YES
3510650	23199801	ED	2	conceived and designed the study protocol	conceived and designed the study protocol	Conceived and designed the experiments	Conceptualization|Methodology	YES
3510650	23199801	FL	2	conceived and designed the study protocol|performed the virological analyses	conceived and designed the study protocol	Conceived and designed the experiments	Conceptualization|Methodology	YES
3510650	23199801	FL	2	conceived and designed the study protocol|performed the virological analyses	performed the virological analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3510650	23199801	FR	2	conceived and designed the study protocol|wrote the initial manuscript	conceived and designed the study protocol	Conceived and designed the experiments	Conceptualization|Methodology	YES
3510650	23199801	FR	2	conceived and designed the study protocol|wrote the initial manuscript	wrote the initial manuscript	Wrote the paper	Writing - Original Draft	YES
3510650	23199801	JPG	2	conceived and designed the study protocol	conceived and designed the study protocol	Conceived and designed the experiments	Conceptualization|Methodology	YES
3510650	23199801	JS	2	were in charge of the patients medical follow-up	were in charge of the patients medical follow-up	-	-	NO
3510650	23199801	LM	2	contributed to the data collection	contributed to the data collection	Performed the experiments	Investigation	YES
3510650	23199801	MP	2	conceived and designed the study protocol	conceived and designed the study protocol	Conceived and designed the experiments	Conceptualization|Methodology	YES
3510650	23199801	SED	2	realized the statistical analysis	realized the statistical analysis	Analyzed the data	Formal analysis	YES
3510650	23199801	VB	2	performed the virological analyses	performed the virological analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3510650	23199801	all authors	2	participated in its final writing and editing	participated in its final writing and editing	Wrote the paper	Writing - Review & Editing	YES
5009568	27589953	All authors	2	agree with the contents of the manuscript	agree with the contents of the manuscript	-	-	NO
5009568	27589953	DS	2	assisted with analysis of green ash data	assisted with analysis of green ash data	Analyzed the data	Formal analysis	YES
5009568	27589953	EAB	2	testing and performed eab testing	testing and performed eab testing	Performed the experiments	Investigation	YES
5009568	27589953	HL	2	performed heat, cold and drought treatments	performed heat, cold and drought treatments	Performed the experiments	Investigation	YES
5009568	27589953	JC	2	conceived of the study and directed the research	conceived of the study and directed the research	Conceived and designed the experiments	Conceptualization|Supervision	YES
5009568	27589953	JD	2	assisted with analysis of green ash data	assisted with analysis of green ash data	Analyzed the data	Formal analysis	YES
5009568	27589953	MC	2	sampled tissues from the adult green ash tree, collected and germinated seed for the full sibling green ash	sampled tissues from the adult green ash tree, collected and germinated seed for the full sibling green ash	Performed the experiments	Investigation	YES
5009568	27589953	MS	2	performed sequence quality trimming and assembly, directed further informatic data analysis and completed writing of the study	performed sequence quality trimming and assembly, directed further informatic data analysis and completed writing of the study	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Supervision	YES
5009568	27589953	NCBI	2	uploaded data to the hardwood genomics website	uploaded data to the hardwood genomics website	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5009568	27589953	NZ	2	performed rna extractions	performed rna extractions	Performed the experiments	Investigation	YES
5009568	27589953	TB	2	performed rna extractions and ozone treatments of seedlings	performed rna extractions and ozone treatments of seedlings	Performed the experiments	Investigation	YES
5009568	27589953	TL	2	performed gene functional characterization and differential expression analysis and wrote part of the manuscript	performed gene functional characterization and differential expression analysis and wrote part of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5009568	27589953	YX	2	performed heat, cold and drought treatments	performed heat, cold and drought treatments	Performed the experiments	Investigation	YES
5439002	28588594	CL	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5439002	28588594	CL	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5439002	28588594	GZ	PLoS52	designed and supervised the study|analyzed the data|prepared the manuscript and all authors read, and approved the manuscript	designed and supervised the study	Conceived and designed the experiments	Methodology|Supervision	YES
5439002	28588594	GZ	PLoS52	designed and supervised the study|analyzed the data|prepared the manuscript and all authors read, and approved the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5439002	28588594	GZ	PLoS52	designed and supervised the study|analyzed the data|prepared the manuscript and all authors read, and approved the manuscript	prepared the manuscript and all authors read, and approved the manuscript	Wrote the paper	Writing - Original Draft	YES
5439002	28588594	HL	PLoS52	designed and supervised the study|analyzed the data|prepared the manuscript and all authors read, and approved the manuscript	designed and supervised the study	Conceived and designed the experiments	Methodology|Supervision	YES
5439002	28588594	HL	PLoS52	designed and supervised the study|analyzed the data|prepared the manuscript and all authors read, and approved the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5439002	28588594	HL	PLoS52	designed and supervised the study|analyzed the data|prepared the manuscript and all authors read, and approved the manuscript	prepared the manuscript and all authors read, and approved the manuscript	Wrote the paper	Writing - Original Draft	YES
5439002	28588594	JW	PLoS52	designed and supervised the study|performed the experiments	designed and supervised the study	Conceived and designed the experiments	Methodology|Supervision	YES
5439002	28588594	JW	PLoS52	designed and supervised the study|performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5439002	28588594	LZ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5439002	28588594	ML	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5439002	28588594	SH	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5439002	28588594	SL	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5439002	28588594	SX	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5439002	28588594	TL	PLoS52	designed and supervised the study|prepared the manuscript and all authors read, and approved the manuscript	designed and supervised the study	Conceived and designed the experiments	Methodology|Supervision	YES
5439002	28588594	TL	PLoS52	designed and supervised the study|prepared the manuscript and all authors read, and approved the manuscript	prepared the manuscript and all authors read, and approved the manuscript	Wrote the paper	Writing - Original Draft	YES
5439002	28588594	XZ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5439002	28588594	YZ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
6409755	30704026	J.L.	CRediT	Data curation|Methodology	Data curation	Analyzed the data	Data curation	YES
6409755	30704026	J.L.	CRediT	Data curation|Methodology	Methodology	Performed the experiments	Methodology	YES
6409755	30704026	J.Q.	CRediT	Data curation|Software	Data curation	Analyzed the data	Data curation	YES
6409755	30704026	J.Q.	CRediT	Data curation|Software	Software	Contributed reagents/materials/analysis tools	Software	YES
6409755	30704026	J.X.	CRediT	Methodology	Methodology	Performed the experiments	Methodology	YES
6409755	30704026	Q.C.	CRediT	Data curation|Formal analysis|Writing--original draft	Data curation	Analyzed the data	Data curation	YES
6409755	30704026	Q.C.	CRediT	Data curation|Formal analysis|Writing--original draft	Formal analysis	Analyzed the data	Formal analysis	YES
6409755	30704026	Q.C.	CRediT	Data curation|Formal analysis|Writing--original draft	Writing--original draft	Wrote the paper	Writing - Original Draft	YES
6409755	30704026	Y.D.	CRediT	Funding acquisition|Investigation|Methodology|Project administration|Writing--review and editing	Funding acquisition	-	Funding acquisition	YES
6409755	30704026	Y.D.	CRediT	Funding acquisition|Investigation|Methodology|Project administration|Writing--review and editing	Investigation	Performed the experiments	Investigation	YES
6409755	30704026	Y.D.	CRediT	Funding acquisition|Investigation|Methodology|Project administration|Writing--review and editing	Methodology	Performed the experiments	Methodology	YES
6409755	30704026	Y.D.	CRediT	Funding acquisition|Investigation|Methodology|Project administration|Writing--review and editing	Project administration	-	Project administration	YES
6409755	30704026	Y.D.	CRediT	Funding acquisition|Investigation|Methodology|Project administration|Writing--review and editing	Writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6409755	30704026	Z.Z.	CRediT	Data curation|Formal analysis|Writing--original draft	Data curation	Analyzed the data	Data curation	YES
6409755	30704026	Z.Z.	CRediT	Data curation|Formal analysis|Writing--original draft	Formal analysis	Analyzed the data	Formal analysis	YES
6409755	30704026	Z.Z.	CRediT	Data curation|Formal analysis|Writing--original draft	Writing--original draft	Wrote the paper	Writing - Original Draft	YES
4398433	25875510	ADA	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398433	25875510	ADM	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4398433	25875510	ALN	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398433	25875510	ALN	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398433	25875510	ALW	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398433	25875510	ALW	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398433	25875510	BLR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398433	25875510	BLR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398433	25875510	BLR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398433	25875510	BLR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398433	25875510	BZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398433	25875510	BZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398433	25875510	BZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398433	25875510	DM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398433	25875510	DM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398433	25875510	DM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398433	25875510	RJO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398433	25875510	RJO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398433	25875510	RJO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398433	25875510	RJO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398433	25875510	TAS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398433	25875510	TAS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398433	25875510	TAS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398433	25875510	TAS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398433	25875510	TYC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5439006	28588602	AF	PLoS52	performed the experiments and analyzed the data|wrote the manuscript	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5439006	28588602	AF	PLoS52	performed the experiments and analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5439006	28588602	All authors	PLoS52	discussed, revised, and approved the manuscript	discussed, revised, and approved the manuscript	Wrote the paper	Writing - Review & Editing	YES
5439006	28588602	CL	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5439006	28588602	FN	PLoS52	conceived and designed the experiments|performed the experiments and analyzed the data|wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5439006	28588602	FN	PLoS52	conceived and designed the experiments|performed the experiments and analyzed the data|wrote the manuscript	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5439006	28588602	FN	PLoS52	conceived and designed the experiments|performed the experiments and analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5439006	28588602	GAS	PLoS52	conceived and designed the experiments|acquired the funds	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5439006	28588602	GAS	PLoS52	conceived and designed the experiments|acquired the funds	acquired the funds	-	Funding acquisition	YES
5439006	28588602	GL	PLoS52	performed the icp-ms analysis	performed the icp-ms analysis	Performed the experiments	Investigation	YES
5439006	28588602	MM	PLoS52	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6409770	30717376	C.R.	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
6409770	30717376	Elisabetta Marini	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
6409770	30717376	Elisabetta Muntoni	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
6409770	30717376	I.C.S.	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
6409770	30717376	K.M.	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
6409770	30717376	L.B.	CRediT	supervision	supervision	-	Supervision	YES
6409770	30717376	L.L.	CRediT	resources	resources	Contributed reagents/materials/analysis tools	Resources	YES
6409770	30717376	M.G.	CRediT	writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6409770	30717376	M.L.	CRediT	funding acquisition	funding acquisition	-	Funding acquisition	YES
5009668	27586631	KK	2	proposed the statistical model and implemented the program for evaluation|developed fundamental environments for the evaluation using simulation and real data studies|carefully checked equations and other contents in this manuscript	proposed the statistical model and implemented the program for evaluation	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation|Methodology	YES
5009668	27586631	KK	2	proposed the statistical model and implemented the program for evaluation|developed fundamental environments for the evaluation using simulation and real data studies|carefully checked equations and other contents in this manuscript	developed fundamental environments for the evaluation using simulation and real data studies	-	Formal analysis	YES
5009668	27586631	KK	2	proposed the statistical model and implemented the program for evaluation|developed fundamental environments for the evaluation using simulation and real data studies|carefully checked equations and other contents in this manuscript	carefully checked equations and other contents in this manuscript	Wrote the paper	Writing - Review & Editing	YES
5009668	27586631	MN	2	developed fundamental environments for the evaluation using simulation and real data studies|carefully checked equations and other contents in this manuscript	developed fundamental environments for the evaluation using simulation and real data studies	-	Formal analysis	YES
5009668	27586631	MN	2	developed fundamental environments for the evaluation using simulation and real data studies|carefully checked equations and other contents in this manuscript	carefully checked equations and other contents in this manuscript	Wrote the paper	Writing - Review & Editing	YES
5009668	27586631	NN	2	developed fundamental environments for the evaluation using simulation and real data studies|carefully checked equations and other contents in this manuscript	developed fundamental environments for the evaluation using simulation and real data studies	-	Formal analysis	YES
5009668	27586631	NN	2	developed fundamental environments for the evaluation using simulation and real data studies|carefully checked equations and other contents in this manuscript	carefully checked equations and other contents in this manuscript	Wrote the paper	Writing - Review & Editing	YES
5009668	27586631	TH	2	carefully checked equations and other contents in this manuscript	carefully checked equations and other contents in this manuscript	Wrote the paper	Writing - Review & Editing	YES
5009668	27586631	TM	2	developed fundamental environments for the evaluation using simulation and real data studies|carefully checked equations and other contents in this manuscript	developed fundamental environments for the evaluation using simulation and real data studies	-	Formal analysis	YES
5009668	27586631	TM	2	developed fundamental environments for the evaluation using simulation and real data studies|carefully checked equations and other contents in this manuscript	carefully checked equations and other contents in this manuscript	Wrote the paper	Writing - Review & Editing	YES
5009668	27586631	YK	2	provided the knowledge and advice about coalescent theory and computational techniques on the field|carefully checked equations and other contents in this manuscript	provided the knowledge and advice about coalescent theory and computational techniques on the field	-	Formal analysis	YES
5009668	27586631	YK	2	provided the knowledge and advice about coalescent theory and computational techniques on the field|carefully checked equations and other contents in this manuscript	carefully checked equations and other contents in this manuscript	Wrote the paper	Writing - Review & Editing	YES
4398434	25874563	EMM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4398434	25874563	EMM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398434	25874563	EV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398434	25874563	EV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398434	25874563	EV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398434	25874563	EV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398434	25874563	JDFF	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398434	25874563	JDFF	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398434	25874563	LPR	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398434	25874563	LRS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398434	25874563	LRS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398434	25874563	LRS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398434	25874563	MMG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398434	25874563	PA	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4398434	25874563	PA	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398434	25874563	PFM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4398434	25874563	PFM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398434	25874563	PGF	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398434	25874563	RR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398434	25874563	RR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398434	25874563	RR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398434	25874563	RR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6409784	30717083	B.B.R.	CRediT	Formal analysis|Investigation|Data curation|Writing-review & editing	Formal analysis	Analyzed the data	Formal analysis	YES
6409784	30717083	B.B.R.	CRediT	Formal analysis|Investigation|Data curation|Writing-review & editing	Investigation	Performed the experiments	Investigation	YES
6409784	30717083	B.B.R.	CRediT	Formal analysis|Investigation|Data curation|Writing-review & editing	Data curation	Analyzed the data	Data curation	YES
6409784	30717083	B.B.R.	CRediT	Formal analysis|Investigation|Data curation|Writing-review & editing	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6409784	30717083	G.N.K.	CRediT	Methodology|Writing-review & editing	Methodology	Performed the experiments	Methodology	YES
6409784	30717083	G.N.K.	CRediT	Methodology|Writing-review & editing	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6409784	30717083	I.M.	CRediT	Formal analysis|Investigation|Data curation|Writing-review & editing|Visualization	Formal analysis	Analyzed the data	Formal analysis	YES
6409784	30717083	I.M.	CRediT	Formal analysis|Investigation|Data curation|Writing-review & editing|Visualization	Investigation	Performed the experiments	Investigation	YES
6409784	30717083	I.M.	CRediT	Formal analysis|Investigation|Data curation|Writing-review & editing|Visualization	Data curation	Analyzed the data	Data curation	YES
6409784	30717083	I.M.	CRediT	Formal analysis|Investigation|Data curation|Writing-review & editing|Visualization	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6409784	30717083	I.M.	CRediT	Formal analysis|Investigation|Data curation|Writing-review & editing|Visualization	Visualization	Analyzed the data	Visualization	YES
6409784	30717083	L.A.W.	CRediT	Conceptualization|Methodology|Resources|Writing-review & editing|Supervision	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6409784	30717083	L.A.W.	CRediT	Conceptualization|Methodology|Resources|Writing-review & editing|Supervision	Methodology	Performed the experiments	Methodology	YES
6409784	30717083	L.A.W.	CRediT	Conceptualization|Methodology|Resources|Writing-review & editing|Supervision	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6409784	30717083	L.A.W.	CRediT	Conceptualization|Methodology|Resources|Writing-review & editing|Supervision	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6409784	30717083	L.A.W.	CRediT	Conceptualization|Methodology|Resources|Writing-review & editing|Supervision	Supervision	-	Supervision	YES
6409784	30717083	N.S.	CRediT	Formal analysis|Investigation|Data curation|Writing-review & editing|Visualization	Formal analysis	Analyzed the data	Formal analysis	YES
6409784	30717083	N.S.	CRediT	Formal analysis|Investigation|Data curation|Writing-review & editing|Visualization	Investigation	Performed the experiments	Investigation	YES
6409784	30717083	N.S.	CRediT	Formal analysis|Investigation|Data curation|Writing-review & editing|Visualization	Data curation	Analyzed the data	Data curation	YES
6409784	30717083	N.S.	CRediT	Formal analysis|Investigation|Data curation|Writing-review & editing|Visualization	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6409784	30717083	N.S.	CRediT	Formal analysis|Investigation|Data curation|Writing-review & editing|Visualization	Visualization	Analyzed the data	Visualization	YES
5009708	27590662	ATG	2	conceived and developed the carp organ viewer	conceived and developed the carp organ viewer	Conceived and designed the experiments	Conceptualization	YES
5009708	27590662	All authors	2	assisted with editing of the manuscript and approved the final version	assisted with editing of the manuscript and approved the final version	Wrote the paper	Writing - Review & Editing	YES
5009708	27590662	BL	2	all contributed to the experiments and their setup	all contributed to the experiments and their setup	Performed the experiments	Investigation	YES
5009708	27590662	CVH	2	designed and supervised the study|contributed to the genome assembly, annotation and analyzed the transcriptomic and proteomic data	designed and supervised the study	Conceived and designed the experiments	Methodology|Supervision	YES
5009708	27590662	CVH	2	designed and supervised the study|contributed to the genome assembly, annotation and analyzed the transcriptomic and proteomic data	contributed to the genome assembly, annotation and analyzed the transcriptomic and proteomic data	Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Formal analysis|Resources	YES
5009708	27590662	DYT	2	conceived and developed the carp organ viewer	conceived and developed the carp organ viewer	Conceived and designed the experiments	Conceptualization	YES
5009708	27590662	GFW	2	all contributed to the experiments and their setup	all contributed to the experiments and their setup	Performed the experiments	Investigation	YES
5009708	27590662	GT	2	contributed to the genome assembly, annotation and analyzed the transcriptomic and proteomic data	contributed to the genome assembly, annotation and analyzed the transcriptomic and proteomic data	Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Formal analysis|Resources	YES
5009708	27590662	HJ	2	all contributed to the experiments and their setup	all contributed to the experiments and their setup	Performed the experiments	Investigation	YES
5009708	27590662	HJJ	2	all contributed to the experiments and their setup	all contributed to the experiments and their setup	Performed the experiments	Investigation	YES
5009708	27590662	HPS	2	designed and supervised the study|contributed to the genome assembly, annotation and analyzed the transcriptomic and proteomic data|wrote the first versions of the manuscript	designed and supervised the study	Conceived and designed the experiments	Methodology|Supervision	YES
5009708	27590662	HPS	2	designed and supervised the study|contributed to the genome assembly, annotation and analyzed the transcriptomic and proteomic data|wrote the first versions of the manuscript	contributed to the genome assembly, annotation and analyzed the transcriptomic and proteomic data	Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Formal analysis|Resources	YES
5009708	27590662	HPS	2	designed and supervised the study|contributed to the genome assembly, annotation and analyzed the transcriptomic and proteomic data|wrote the first versions of the manuscript	wrote the first versions of the manuscript	Wrote the paper	Writing - Original Draft	YES
5009708	27590662	ICRMK	2	contributed to the genome assembly, annotation and analyzed the transcriptomic and proteomic data|wrote the first versions of the manuscript	contributed to the genome assembly, annotation and analyzed the transcriptomic and proteomic data	Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Formal analysis|Resources	YES
5009708	27590662	ICRMK	2	contributed to the genome assembly, annotation and analyzed the transcriptomic and proteomic data|wrote the first versions of the manuscript	wrote the first versions of the manuscript	Wrote the paper	Writing - Original Draft	YES
5009708	27590662	II	2	all contributed to the experiments and their setup	all contributed to the experiments and their setup	Performed the experiments	Investigation	YES
5009708	27590662	JTD	2	all contributed to the experiments and their setup	all contributed to the experiments and their setup	Performed the experiments	Investigation	YES
5009708	27590662	MF	2	all contributed to the experiments and their setup	all contributed to the experiments and their setup	Performed the experiments	Investigation	YES
5009708	27590662	MN	2	all contributed to the experiments and their setup	all contributed to the experiments and their setup	Performed the experiments	Investigation	YES
5009708	27590662	MP	2	contributed to the genome assembly, annotation and analyzed the transcriptomic and proteomic data|conceived and developed the carp organ viewer	contributed to the genome assembly, annotation and analyzed the transcriptomic and proteomic data	Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Formal analysis|Resources	YES
5009708	27590662	MP	2	contributed to the genome assembly, annotation and analyzed the transcriptomic and proteomic data|conceived and developed the carp organ viewer	conceived and developed the carp organ viewer	Conceived and designed the experiments	Conceptualization	YES
5009708	27590662	RD	2	all contributed to the experiments and their setup	all contributed to the experiments and their setup	Performed the experiments	Investigation	YES
5009708	27590662	SJPD	2	contributed to the genome assembly, annotation and analyzed the transcriptomic and proteomic data|all contributed to the experiments and their setup|wrote the first versions of the manuscript	contributed to the genome assembly, annotation and analyzed the transcriptomic and proteomic data	Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Formal analysis|Resources	YES
5009708	27590662	SJPD	2	contributed to the genome assembly, annotation and analyzed the transcriptomic and proteomic data|all contributed to the experiments and their setup|wrote the first versions of the manuscript	all contributed to the experiments and their setup	Performed the experiments	Investigation	YES
5009708	27590662	SJPD	2	contributed to the genome assembly, annotation and analyzed the transcriptomic and proteomic data|all contributed to the experiments and their setup|wrote the first versions of the manuscript	wrote the first versions of the manuscript	Wrote the paper	Writing - Original Draft	YES
5009708	27590662	SYA	2	all contributed to the experiments and their setup	all contributed to the experiments and their setup	Performed the experiments	Investigation	YES
5009708	27590662	TM	2	all contributed to the experiments and their setup	all contributed to the experiments and their setup	Performed the experiments	Investigation	YES
4398435	25874407	AC	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398435	25874407	AC	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398435	25874407	KL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398435	25874407	KL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398435	25874407	KL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398435	25874407	KL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398435	25874407	NR	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398435	25874407	NR	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398435	25874407	RK	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398435	25874407	RK	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398435	25874407	WIM	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398435	25874407	WIM	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5440519	28588592	GC	2	refine and approved the manuscript	refine and approved the manuscript	-	-	NO
5440519	28588592	HR	2	proposed and wrote the manuscript	proposed and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5440519	28588592	ID	2	refine and approved the manuscript	refine and approved the manuscript	-	-	NO
5440519	28588592	MN	2	proposed and wrote the manuscript	proposed and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5440519	28588592	SK	2	managed the graphics	managed the graphics	-	-	NO
5440519	28588592	SY	2	refine and approved the manuscript	refine and approved the manuscript	-	-	NO
5440519	28588592	ZS	2	managed the graphics	managed the graphics	-	-	NO
6409804	30744157	C.W.	CRediT	Writing--review and editing	Writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6409804	30744157	G.Z.	CRediT	Conceptualization|Project administration|Resources	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6409804	30744157	G.Z.	CRediT	Conceptualization|Project administration|Resources	Project administration	-	Project administration	YES
6409804	30744157	G.Z.	CRediT	Conceptualization|Project administration|Resources	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6409804	30744157	L.O.	CRediT	Software	Software	Contributed reagents/materials/analysis tools	Software	YES
6409804	30744157	Q.Z.	CRediT	Conceptualization|Writing--original draft	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6409804	30744157	Q.Z.	CRediT	Conceptualization|Writing--original draft	Writing--original draft	Wrote the paper	Writing - Original Draft	YES
6409804	30744157	S.Z.	CRediT	Data curation	Data curation	Analyzed the data	Data curation	YES
6409804	30744157	Y.C.	CRediT	Supervision	Supervision	-	Supervision	YES
6409804	30744157	Y.Z.	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
6409804	30744157	Z.L.	CRediT	Software	Software	Contributed reagents/materials/analysis tools	Software	YES
4398436	25874411	BO	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398436	25874411	BO	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398436	25874411	BO	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398436	25874411	CCW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Responsible for final content	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398436	25874411	CCW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Responsible for final content	Analyzed the data	Analyzed the data	Formal analysis	YES
4398436	25874411	CCW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Responsible for final content	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398436	25874411	CCW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Responsible for final content	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398436	25874411	CCW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Responsible for final content	Responsible for final content	-	-	NO
4398436	25874411	EK	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398436	25874411	EK	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398436	25874411	EK	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398436	25874411	EK	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398436	25874411	EM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Responsible for final content	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398436	25874411	EM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Responsible for final content	Performed the experiments	Performed the experiments	Investigation	YES
4398436	25874411	EM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Responsible for final content	Analyzed the data	Analyzed the data	Formal analysis	YES
4398436	25874411	EM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Responsible for final content	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398436	25874411	EM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Responsible for final content	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398436	25874411	EM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Responsible for final content	Responsible for final content	-	-	NO
4398436	25874411	FAK	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398436	25874411	FAK	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398436	25874411	FAK	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398436	25874411	FAK	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398436	25874411	HMB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398436	25874411	HMB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398436	25874411	HMB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398436	25874411	HMB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398436	25874411	HMB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398436	25874411	MLJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398436	25874411	MLJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398436	25874411	MLJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398436	25874411	MLJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398436	25874411	MO	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398436	25874411	MO	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398436	25874411	MO	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398436	25874411	MO	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398436	25874411	PMM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Responsible for final content	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398436	25874411	PMM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Responsible for final content	Performed the experiments	Performed the experiments	Investigation	YES
4398436	25874411	PMM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Responsible for final content	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398436	25874411	PMM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Responsible for final content	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398436	25874411	PMM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Responsible for final content	Responsible for final content	-	-	NO
4398436	25874411	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Responsible for final content	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398436	25874411	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Responsible for final content	Performed the experiments	Performed the experiments	Investigation	YES
4398436	25874411	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Responsible for final content	Analyzed the data	Analyzed the data	Formal analysis	YES
4398436	25874411	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Responsible for final content	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398436	25874411	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Responsible for final content	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398436	25874411	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Responsible for final content	Responsible for final content	-	-	NO
4398436	25874411	VK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Responsible for final content	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398436	25874411	VK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Responsible for final content	Performed the experiments	Performed the experiments	Investigation	YES
4398436	25874411	VK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Responsible for final content	Analyzed the data	Analyzed the data	Formal analysis	YES
4398436	25874411	VK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Responsible for final content	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398436	25874411	VK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Responsible for final content	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398436	25874411	VK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Responsible for final content	Responsible for final content	-	-	NO
5009821	27586009	HL	2	implemented the web tool|wrote this manuscript	implemented the web tool	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5009821	27586009	HL	2	implemented the web tool|wrote this manuscript	wrote this manuscript	Wrote the paper	Writing - Original Draft	YES
5009821	27586009	JC	2	designed the web tool framework|wrote this manuscript	designed the web tool framework	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
5009821	27586009	JC	2	designed the web tool framework|wrote this manuscript	wrote this manuscript	Wrote the paper	Writing - Original Draft	YES
5009821	27586009	JP	2	implemented the web tool|wrote this manuscript	implemented the web tool	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5009821	27586009	JP	2	implemented the web tool|wrote this manuscript	wrote this manuscript	Wrote the paper	Writing - Original Draft	YES
5009821	27586009	LJ	2	helped design the visualization interface	helped design the visualization interface	Conceived and designed the experiments|Analyzed the data	Visualization	YES
5009821	27586009	QJ	2	helped design the input interface	helped design the input interface	Conceived and designed the experiments	-	YES
5009821	27586009	YL	2	helped design the visualization interface	helped design the visualization interface	Conceived and designed the experiments|Analyzed the data	Visualization	YES
5009821	27586009	YW	2	designed the web tool framework	designed the web tool framework	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
5440559	28588600	BA	2	extracted data from literature and helped in draw the chemical structures of the compounds	extracted data from literature and helped in draw the chemical structures of the compounds	Performed the experiments	Investigation	YES
5440559	28588600	JHA	2	extracted data from literature and helped in draw the chemical structures of the compounds	extracted data from literature and helped in draw the chemical structures of the compounds	Performed the experiments	Investigation	YES
5440559	28588600	JSA	2	extracted data from literature and helped in draw the chemical structures of the compounds	extracted data from literature and helped in draw the chemical structures of the compounds	Performed the experiments	Investigation	YES
5440559	28588600	RA	2	extracted data from literature and helped in draw the chemical structures of the compounds	extracted data from literature and helped in draw the chemical structures of the compounds	Performed the experiments	Investigation	YES
5440559	28588600	YB	2	wrote and finalized the manuscript	wrote and finalized the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6409818	30717419	A.B.-M.	CRediT	Conceptualization|Writing - review & editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6409818	30717419	A.B.-M.	CRediT	Conceptualization|Writing - review & editing	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
6409818	30717419	A.C.-C.	CRediT	Conceptualization|Writing - review & editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6409818	30717419	A.C.-C.	CRediT	Conceptualization|Writing - review & editing	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
6409818	30717419	B.C.-N.	CRediT	Conceptualization	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6409818	30717419	E.B.	CRediT	investigation|writing-original draft preparation	investigation	Performed the experiments	Investigation	YES
6409818	30717419	E.B.	CRediT	investigation|writing-original draft preparation	writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
6409818	30717419	J.S.-C.	CRediT	Conceptualization|investigation|Writing - review & editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6409818	30717419	J.S.-C.	CRediT	Conceptualization|investigation|Writing - review & editing	investigation	Performed the experiments	Investigation	YES
6409818	30717419	J.S.-C.	CRediT	Conceptualization|investigation|Writing - review & editing	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
6409818	30717419	J.Z.-L.	CRediT	investigation|writing-original draft preparation	investigation	Performed the experiments	Investigation	YES
6409818	30717419	J.Z.-L.	CRediT	investigation|writing-original draft preparation	writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
6409818	30717419	L.H.-B.	CRediT	Writing - review & editing|funding acquisition	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
6409818	30717419	L.H.-B.	CRediT	Writing - review & editing|funding acquisition	funding acquisition	-	Funding acquisition	YES
6409818	30717419	M.J.R.-L.	CRediT	investigation	investigation	Performed the experiments	Investigation	YES
4398438	25875252	ASM	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398438	25875252	ASM	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398438	25875252	JC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Screening review of maternal and neonatal health program assessment protocols, clinical standards, and process of care guidelines	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398438	25875252	JC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Screening review of maternal and neonatal health program assessment protocols, clinical standards, and process of care guidelines	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398438	25875252	JC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Screening review of maternal and neonatal health program assessment protocols, clinical standards, and process of care guidelines	Screening review of maternal and neonatal health program assessment protocols, clinical standards, and process of care guidelines	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4398438	25875252	MDA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398438	25875252	MDA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398438	25875252	MDA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398438	25875252	MS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398438	25875252	MS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398438	25875252	SB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Screening review of maternal and neonatal health program assessment protocols, clinical standards, and process of care guidelines	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398438	25875252	SB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Screening review of maternal and neonatal health program assessment protocols, clinical standards, and process of care guidelines	Analyzed the data	Analyzed the data	Formal analysis	YES
4398438	25875252	SB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Screening review of maternal and neonatal health program assessment protocols, clinical standards, and process of care guidelines	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398438	25875252	SB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Screening review of maternal and neonatal health program assessment protocols, clinical standards, and process of care guidelines	Screening review of maternal and neonatal health program assessment protocols, clinical standards, and process of care guidelines	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4398438	25875252	SG	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6409859	30781722	A.B.	CRediT	Supervision	Supervision	-	Supervision	YES
6409859	30781722	A.R.P.	CRediT	Conceptualization|Resources	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6409859	30781722	A.R.P.	CRediT	Conceptualization|Resources	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6409859	30781722	F.A.B.	CRediT	Methodology|Investigation|Writing--original draft preparation|Writing--review & editing	Methodology	Performed the experiments	Methodology	YES
6409859	30781722	F.A.B.	CRediT	Methodology|Investigation|Writing--original draft preparation|Writing--review & editing	Investigation	Performed the experiments	Investigation	YES
6409859	30781722	F.A.B.	CRediT	Methodology|Investigation|Writing--original draft preparation|Writing--review & editing	Writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6409859	30781722	F.A.B.	CRediT	Methodology|Investigation|Writing--original draft preparation|Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6409859	30781722	F.S.	CRediT	Conceptualization|Writing--review & editing|Supervision	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6409859	30781722	F.S.	CRediT	Conceptualization|Writing--review & editing|Supervision	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6409859	30781722	F.S.	CRediT	Conceptualization|Writing--review & editing|Supervision	Supervision	-	Supervision	YES
6409859	30781722	G.C.	CRediT	Supervision	Supervision	-	Supervision	YES
6409859	30781722	G.D.S.	CRediT	Methodology	Methodology	Performed the experiments	Methodology	YES
6409859	30781722	G.G.P.	CRediT	Methodology	Methodology	Performed the experiments	Methodology	YES
6409859	30781722	L.T.F.	CRediT	Methodology	Methodology	Performed the experiments	Methodology	YES
6409859	30781722	M.M.	CRediT	Methodology	Methodology	Performed the experiments	Methodology	YES
6409859	30781722	S.P.	CRediT	Methodology|Investigation|Writing--original draft preparation	Methodology	Performed the experiments	Methodology	YES
6409859	30781722	S.P.	CRediT	Methodology|Investigation|Writing--original draft preparation	Investigation	Performed the experiments	Investigation	YES
6409859	30781722	S.P.	CRediT	Methodology|Investigation|Writing--original draft preparation	Writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6409859	30781722	S.S.G.	CRediT	Conceptualization|Resources	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6409859	30781722	S.S.G.	CRediT	Conceptualization|Resources	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6409859	30781722	T.A.	CRediT	Methodology	Methodology	Performed the experiments	Methodology	YES
5440560	28588595	AG-F	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5440560	28588595	CFe	PLoS52	performed the experiments|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5440560	28588595	CFe	PLoS52	performed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5440560	28588595	CFo	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5440560	28588595	VS-G	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5009874	27586787	AB	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5009874	27586787	AO	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5009874	27586787	CL	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5009874	27586787	DKPK	PLoS52	performed the experiments|analyzed the data|prepared the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5009874	27586787	DKPK	PLoS52	performed the experiments|analyzed the data|prepared the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5009874	27586787	DKPK	PLoS52	performed the experiments|analyzed the data|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5009874	27586787	IIM	PLoS52	developed the bioinformatics pipeline used for the analysis	developed the bioinformatics pipeline used for the analysis	-	Formal analysis	YES
5009874	27586787	MB	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5009874	27586787	RNK	PLoS52	designed the experiment|performed the experiments|analyzed the data|prepared the manuscript	designed the experiment	Conceived and designed the experiments	Methodology	YES
5009874	27586787	RNK	PLoS52	designed the experiment|performed the experiments|analyzed the data|prepared the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5009874	27586787	RNK	PLoS52	designed the experiment|performed the experiments|analyzed the data|prepared the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5009874	27586787	RNK	PLoS52	designed the experiment|performed the experiments|analyzed the data|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5009874	27586787	SA	PLoS52	developed the bioinformatics pipeline used for the analysis|analyzed the data|prepared the manuscript	developed the bioinformatics pipeline used for the analysis	-	Formal analysis	YES
5009874	27586787	SA	PLoS52	developed the bioinformatics pipeline used for the analysis|analyzed the data|prepared the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5009874	27586787	SA	PLoS52	developed the bioinformatics pipeline used for the analysis|analyzed the data|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
6409895	30759879	A.O.	CRediT	Conceptualization|Data curation|Formal analysis|Methodology|Resources|Writing--original draft	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6409895	30759879	A.O.	CRediT	Conceptualization|Data curation|Formal analysis|Methodology|Resources|Writing--original draft	Data curation	Analyzed the data	Data curation	YES
6409895	30759879	A.O.	CRediT	Conceptualization|Data curation|Formal analysis|Methodology|Resources|Writing--original draft	Formal analysis	Analyzed the data	Formal analysis	YES
6409895	30759879	A.O.	CRediT	Conceptualization|Data curation|Formal analysis|Methodology|Resources|Writing--original draft	Methodology	Performed the experiments	Methodology	YES
6409895	30759879	A.O.	CRediT	Conceptualization|Data curation|Formal analysis|Methodology|Resources|Writing--original draft	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6409895	30759879	A.O.	CRediT	Conceptualization|Data curation|Formal analysis|Methodology|Resources|Writing--original draft	Writing--original draft	Wrote the paper	Writing - Original Draft	YES
6409895	30759879	C.O.	CRediT	Formal analysis|Writing--review & editing	Formal analysis	Analyzed the data	Formal analysis	YES
6409895	30759879	C.O.	CRediT	Formal analysis|Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6409895	30759879	G.B.	CRediT	Resources|Validation|Writing--review & editing	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6409895	30759879	G.B.	CRediT	Resources|Validation|Writing--review & editing	Validation	Performed the experiments	Validation	YES
6409895	30759879	G.B.	CRediT	Resources|Validation|Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6409895	30759879	J.A.M.	CRediT	Conceptualization|Data curation|Formal analysis|Funding acquisition|Investigation|Methodology|Project administration|Writing--original draft|Writing--review & editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6409895	30759879	J.A.M.	CRediT	Conceptualization|Data curation|Formal analysis|Funding acquisition|Investigation|Methodology|Project administration|Writing--original draft|Writing--review & editing	Data curation	Analyzed the data	Data curation	YES
6409895	30759879	J.A.M.	CRediT	Conceptualization|Data curation|Formal analysis|Funding acquisition|Investigation|Methodology|Project administration|Writing--original draft|Writing--review & editing	Formal analysis	Analyzed the data	Formal analysis	YES
6409895	30759879	J.A.M.	CRediT	Conceptualization|Data curation|Formal analysis|Funding acquisition|Investigation|Methodology|Project administration|Writing--original draft|Writing--review & editing	Funding acquisition	-	Funding acquisition	YES
6409895	30759879	J.A.M.	CRediT	Conceptualization|Data curation|Formal analysis|Funding acquisition|Investigation|Methodology|Project administration|Writing--original draft|Writing--review & editing	Investigation	Performed the experiments	Investigation	YES
6409895	30759879	J.A.M.	CRediT	Conceptualization|Data curation|Formal analysis|Funding acquisition|Investigation|Methodology|Project administration|Writing--original draft|Writing--review & editing	Methodology	Performed the experiments	Methodology	YES
6409895	30759879	J.A.M.	CRediT	Conceptualization|Data curation|Formal analysis|Funding acquisition|Investigation|Methodology|Project administration|Writing--original draft|Writing--review & editing	Project administration	-	Project administration	YES
6409895	30759879	J.A.M.	CRediT	Conceptualization|Data curation|Formal analysis|Funding acquisition|Investigation|Methodology|Project administration|Writing--original draft|Writing--review & editing	Writing--original draft	Wrote the paper	Writing - Original Draft	YES
6409895	30759879	J.A.M.	CRediT	Conceptualization|Data curation|Formal analysis|Funding acquisition|Investigation|Methodology|Project administration|Writing--original draft|Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6409895	30759879	M.A.B.	CRediT	Conceptualization|Investigation|Project administration|Resources|Writing--review & editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6409895	30759879	M.A.B.	CRediT	Conceptualization|Investigation|Project administration|Resources|Writing--review & editing	Investigation	Performed the experiments	Investigation	YES
6409895	30759879	M.A.B.	CRediT	Conceptualization|Investigation|Project administration|Resources|Writing--review & editing	Project administration	-	Project administration	YES
6409895	30759879	M.A.B.	CRediT	Conceptualization|Investigation|Project administration|Resources|Writing--review & editing	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6409895	30759879	M.A.B.	CRediT	Conceptualization|Investigation|Project administration|Resources|Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6409895	30759879	M.J.	CRediT	Resources|Validation|Writing--review & editing	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6409895	30759879	M.J.	CRediT	Resources|Validation|Writing--review & editing	Validation	Performed the experiments	Validation	YES
6409895	30759879	M.J.	CRediT	Resources|Validation|Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6409895	30759879	R.M.	CRediT	Conceptualization|Funding acquisition|Investigation|Project administration|Resources|Writing--original draft|Writing--review & editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6409895	30759879	R.M.	CRediT	Conceptualization|Funding acquisition|Investigation|Project administration|Resources|Writing--original draft|Writing--review & editing	Funding acquisition	-	Funding acquisition	YES
6409895	30759879	R.M.	CRediT	Conceptualization|Funding acquisition|Investigation|Project administration|Resources|Writing--original draft|Writing--review & editing	Investigation	Performed the experiments	Investigation	YES
6409895	30759879	R.M.	CRediT	Conceptualization|Funding acquisition|Investigation|Project administration|Resources|Writing--original draft|Writing--review & editing	Project administration	-	Project administration	YES
6409895	30759879	R.M.	CRediT	Conceptualization|Funding acquisition|Investigation|Project administration|Resources|Writing--original draft|Writing--review & editing	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6409895	30759879	R.M.	CRediT	Conceptualization|Funding acquisition|Investigation|Project administration|Resources|Writing--original draft|Writing--review & editing	Writing--original draft	Wrote the paper	Writing - Original Draft	YES
6409895	30759879	R.M.	CRediT	Conceptualization|Funding acquisition|Investigation|Project administration|Resources|Writing--original draft|Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
4441279	24602075	Both authors	2	were involved in revising drafts to publication and approved the decision to submit	were involved in revising drafts to publication and approved the decision to submit	Wrote the paper	Writing - Original Draft	YES
4441279	24602075	J.M.	2	produced the first draft of this paper	produced the first draft of this paper	Wrote the paper	Writing - Original Draft	YES
4410749	25954756	Florian G. Metzger	2	designed the study and drafted it	designed the study and drafted it	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4410749	25954756	Janina Geib	2	designed the study and drafted it	designed the study and drafted it	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4398439	25875200	CYT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398439	25875200	CYT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4398439	25875200	CYT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4398439	25875200	JDG	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398439	25875200	JMJ	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398439	25875200	JMJ	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398439	25875200	JRM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398439	25875200	JRM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398439	25875200	JRM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398439	25875200	JRM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398439	25875200	KPC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398439	25875200	LRC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398439	25875200	LRC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4398439	25875200	LRC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4398439	25875200	MMM	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398439	25875200	MMM	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398439	25875200	MPK	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398439	25875200	PHF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398439	25875200	PHF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398439	25875200	PHF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398439	25875200	PHF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398439	25875200	RMV	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398439	25875200	RMV	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398439	25875200	TRM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5010666	27590916	CN	2	edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5010666	27590916	HY	2	performed the analysis	performed the analysis	Performed the experiments	Investigation	YES
5010666	27590916	SLS	2	designed the study and wrote the manuscript|performed the analysis	designed the study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5010666	27590916	SLS	2	designed the study and wrote the manuscript|performed the analysis	performed the analysis	Performed the experiments	Investigation	YES
5010666	27590916	ST	2	designed the study and wrote the manuscript|performed the analysis	designed the study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5010666	27590916	ST	2	designed the study and wrote the manuscript|performed the analysis	performed the analysis	Performed the experiments	Investigation	YES
5440562	28588590	CT	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5440562	28588590	EG-G	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5440562	28588590	JO	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5440562	28588590	MN	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5440562	28588590	PC	2	performed experiments, and wrote the manuscript	performed experiments, and wrote the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6409946	30795589	C.Y.	CRediT	methodology	methodology	Performed the experiments	Methodology	YES
6409946	30795589	F.H.	CRediT	Conceptualization|methodology|formal analysis|investigation|data curation|writing--original draft preparation|visualization	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6409946	30795589	F.H.	CRediT	Conceptualization|methodology|formal analysis|investigation|data curation|writing--original draft preparation|visualization	methodology	Performed the experiments	Methodology	YES
6409946	30795589	F.H.	CRediT	Conceptualization|methodology|formal analysis|investigation|data curation|writing--original draft preparation|visualization	formal analysis	Analyzed the data	Formal analysis	YES
6409946	30795589	F.H.	CRediT	Conceptualization|methodology|formal analysis|investigation|data curation|writing--original draft preparation|visualization	investigation	Performed the experiments	Investigation	YES
6409946	30795589	F.H.	CRediT	Conceptualization|methodology|formal analysis|investigation|data curation|writing--original draft preparation|visualization	data curation	Analyzed the data	Data curation	YES
6409946	30795589	F.H.	CRediT	Conceptualization|methodology|formal analysis|investigation|data curation|writing--original draft preparation|visualization	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6409946	30795589	F.H.	CRediT	Conceptualization|methodology|formal analysis|investigation|data curation|writing--original draft preparation|visualization	visualization	Analyzed the data	Visualization	YES
6409946	30795589	J.L.	CRediT	validation|project administration	validation	Performed the experiments	Validation	YES
6409946	30795589	J.L.	CRediT	validation|project administration	project administration	-	Project administration	YES
6409946	30795589	J.X.	CRediT	Conceptualization	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6409946	30795589	L.T.	CRediT	Conceptualization|resources|supervision|project administration|project administration	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6409946	30795589	L.T.	CRediT	Conceptualization|resources|supervision|project administration|project administration	resources	Contributed reagents/materials/analysis tools	Resources	YES
6409946	30795589	L.T.	CRediT	Conceptualization|resources|supervision|project administration|project administration	supervision	-	Supervision	YES
6409946	30795589	L.T.	CRediT	Conceptualization|resources|supervision|project administration|project administration	project administration	-	Project administration	YES
6409946	30795589	L.T.	CRediT	Conceptualization|resources|supervision|project administration|project administration	project administration	-	Project administration	YES
6409946	30795589	L.Z.	CRediT	methodology	methodology	Performed the experiments	Methodology	YES
6409946	30795589	Q.M.	CRediT	validation|supervision	validation	Performed the experiments	Validation	YES
6409946	30795589	Q.M.	CRediT	validation|supervision	supervision	-	Supervision	YES
6409946	30795589	R.J.L.	CRediT	writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6409946	30795589	S.D.	CRediT	software	software	Contributed reagents/materials/analysis tools	Software	YES
6409946	30795589	Y.S.	CRediT	methodology	methodology	Performed the experiments	Methodology	YES
6409946	30795589	Z.C.	CRediT	validation	validation	Performed the experiments	Validation	YES
4398440	25875815	AW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398440	25875815	AW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398440	25875815	AW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398440	25875815	AW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398440	25875815	DOF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398440	25875815	DOF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398440	25875815	DOF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398440	25875815	DOF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398440	25875815	FW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398440	25875815	FW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4398440	25875815	FW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4398440	25875815	GH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398440	25875815	GH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398440	25875815	GH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398440	25875815	JD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398440	25875815	JD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4398440	25875815	JD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4398440	25875815	VKP	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5010698	27589862	All authors	2	participated in the drafting of the manuscript, and read and approved the final manuscript	participated in the drafting of the manuscript, and read and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5010698	27589862	CAH	2	conceived of the study, designed the study and participated in the analysis of the data	conceived of the study, designed the study and participated in the analysis of the data	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
5010698	27589862	GFB	2	conceived of the study, designed the study and participated in the analysis of the data	conceived of the study, designed the study and participated in the analysis of the data	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
5010698	27589862	JH	2	carried out the experiments, including sample collection, sample preparation, genome assembly and annotation and the molecular genetic studies discussed	carried out the experiments, including sample collection, sample preparation, genome assembly and annotation and the molecular genetic studies discussed	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5010698	27589862	JMD	2	conceived of the study, designed the study and participated in the analysis of the data	conceived of the study, designed the study and participated in the analysis of the data	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
5010698	27589862	JRG	2	carried out the experiments, including sample collection, sample preparation, genome assembly and annotation and the molecular genetic studies discussed|conceived of the study, designed the study and participated in the analysis of the data	carried out the experiments, including sample collection, sample preparation, genome assembly and annotation and the molecular genetic studies discussed	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5010698	27589862	JRG	2	carried out the experiments, including sample collection, sample preparation, genome assembly and annotation and the molecular genetic studies discussed|conceived of the study, designed the study and participated in the analysis of the data	conceived of the study, designed the study and participated in the analysis of the data	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
5010698	27589862	MJS	2	carried out the experiments, including sample collection, sample preparation, genome assembly and annotation and the molecular genetic studies discussed	carried out the experiments, including sample collection, sample preparation, genome assembly and annotation and the molecular genetic studies discussed	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5010698	27589862	NF	2	carried out the experiments, including sample collection, sample preparation, genome assembly and annotation and the molecular genetic studies discussed	carried out the experiments, including sample collection, sample preparation, genome assembly and annotation and the molecular genetic studies discussed	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5010698	27589862	NJ	2	carried out the experiments, including sample collection, sample preparation, genome assembly and annotation and the molecular genetic studies discussed	carried out the experiments, including sample collection, sample preparation, genome assembly and annotation and the molecular genetic studies discussed	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5010698	27589862	PKV	2	carried out the experiments, including sample collection, sample preparation, genome assembly and annotation and the molecular genetic studies discussed	carried out the experiments, including sample collection, sample preparation, genome assembly and annotation and the molecular genetic studies discussed	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5440745	28588601	All authors	2	listed, have made substantial, direct and intellectual contribution to the work, and approved it for publication	listed, have made substantial, direct and intellectual contribution to the work, and approved it for publication	-	-	NO
6409996	30678207	B.W.	CRediT	Funding acquisition|Project administration|Supervision|Writing--original draft	Funding acquisition	-	Funding acquisition	YES
6409996	30678207	B.W.	CRediT	Funding acquisition|Project administration|Supervision|Writing--original draft	Project administration	-	Project administration	YES
6409996	30678207	B.W.	CRediT	Funding acquisition|Project administration|Supervision|Writing--original draft	Supervision	-	Supervision	YES
6409996	30678207	B.W.	CRediT	Funding acquisition|Project administration|Supervision|Writing--original draft	Writing--original draft	Wrote the paper	Writing - Original Draft	YES
6409996	30678207	H.W.	CRediT	Data curation	Data curation	Analyzed the data	Data curation	YES
6409996	30678207	M.L.	CRediT	Methodology	Methodology	Performed the experiments	Methodology	YES
6409996	30678207	M.W.	CRediT	Resources|Validation|Writing--review & editing	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6409996	30678207	M.W.	CRediT	Resources|Validation|Writing--review & editing	Validation	Performed the experiments	Validation	YES
6409996	30678207	M.W.	CRediT	Resources|Validation|Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6409996	30678207	W.Y.	CRediT	Validation	Validation	Performed the experiments	Validation	YES
6409996	30678207	Y.W.	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
4398441	25874690	JY	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4398441	25874690	QCZ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398441	25874690	QCZ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398441	25874690	QCZ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398441	25874690	WCY	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398441	25874690	XKM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398441	25874690	XRC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398441	25874690	XRC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398441	25874690	XRC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398441	25874690	YZF	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4398441	25874690	ZHX	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4811091	27066068	Jianfei Yang	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
4811091	27066068	Jiquan Yang	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
4811091	27066068	Yudong Zhang	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
5440749	28588603	All authors	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5440749	28588603	MB	2	has participated in the design of the experiments, the analytical determinations and the writing and discussion of the manuscript	has participated in the design of the experiments, the analytical determinations and the writing and discussion of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5440749	28588603	MG-L	2	has participated in the design of the experiments and the analytical determinations	has participated in the design of the experiments and the analytical determinations	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5440749	28588603	MP	2	has participated in the design of the experiments, the analytical determinations and the writing and discussion of the manuscript	has participated in the design of the experiments, the analytical determinations and the writing and discussion of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5440749	28588603	MS	2	has participated in the design of the experiments, the analytical determinations and the writing and discussion of the manuscript	has participated in the design of the experiments, the analytical determinations and the writing and discussion of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5440749	28588603	PZ	2	has participated in the design of the experiments and the analytical determinations	has participated in the design of the experiments and the analytical determinations	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6409998	30759886	A.J.A.	2	designed and supervised the experiments	designed and supervised the experiments	Conceived and designed the experiments	Methodology|Supervision	YES
6409998	30759886	A.M.-G.	2	designed and supervised the experiments	designed and supervised the experiments	Conceived and designed the experiments	Methodology|Supervision	YES
6409998	30759886	A.S.	2	developed the hplc method	developed the hplc method	Performed the experiments	Investigation|Methodology	YES
6409998	30759886	All authors	2	contributed for the manuscript preparation	contributed for the manuscript preparation	Wrote the paper	Writing - Original Draft	YES
6409998	30759886	D.M.	2	prepared the formulations and performed the stability studies	prepared the formulations and performed the stability studies	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
6409998	30759886	H.G.	2	performed the in vitro characterisation studies	performed the in vitro characterisation studies	Performed the experiments	Investigation	YES
6409998	30759886	H.M.R.	2	designed and supervised the experiments	designed and supervised the experiments	Conceived and designed the experiments	Methodology|Supervision	YES
6409998	30759886	J.M.	2	performed the in vitro characterisation studies	performed the in vitro characterisation studies	Performed the experiments	Investigation	YES
6409998	30759886	P.M.	2	performed the sterility studies	performed the sterility studies	Performed the experiments	Investigation	YES
6409998	30759886	P.T.	2	performed the in vitro characterisation studies	performed the in vitro characterisation studies	Performed the experiments	Investigation	YES
4398442	25875965	KB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398442	25875965	KB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398442	25875965	KB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398442	25875965	KB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398442	25875965	KB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398442	25875965	NN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398442	25875965	NN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398442	25875965	NN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398442	25875965	NN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398442	25875965	SC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398442	25875965	SC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398442	25875965	SC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398442	25875965	SC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5011782	27595844	AH	PLoS5	Contributed reagents/materials	Contributed reagents/materials	Contributed reagents/materials/analysis tools	Resources	YES
5011782	27595844	AL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5011782	27595844	CG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5011782	27595844	IC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5011782	27595844	IC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5011782	27595844	IC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5011782	27595844	JC	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5011782	27595844	JC	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5011782	27595844	JR	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5011782	27595844	LH	PLoS5	Contributed reagents/materials	Contributed reagents/materials	Contributed reagents/materials/analysis tools	Resources	YES
5011782	27595844	MM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5011782	27595844	PS	PLoS5	Contributed reagents/materials	Contributed reagents/materials	Contributed reagents/materials/analysis tools	Resources	YES
5011782	27595844	SG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5011782	27595844	SW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411446	25954752	All authors	2	contributed to the analysis of the results and the preparation of the paper	contributed to the analysis of the results and the preparation of the paper	Analyzed the data	Formal analysis	YES
4411446	25954752	Sabina Islam	2	performed the biofilm experiments	performed the biofilm experiments	Performed the experiments	Investigation	YES
4411446	25954752	Zhaobin Xu	2	contributed to the design and coordination of the study|performed the computational implementations	contributed to the design and coordination of the study	Conceived and designed the experiments	Methodology|Project administration	YES
4411446	25954752	Zhaobin Xu	2	contributed to the design and coordination of the study|performed the computational implementations	performed the computational implementations	Performed the experiments	Formal analysis|Investigation	YES
4411446	25954752	Zuyi Huang	2	contributed to the design and coordination of the study|supervised the computational aspects of the work	contributed to the design and coordination of the study	Conceived and designed the experiments	Methodology|Project administration	YES
4411446	25954752	Zuyi Huang	2	contributed to the design and coordination of the study|supervised the computational aspects of the work	supervised the computational aspects of the work	-	Formal analysis|Supervision	YES
5440764	28588604	LS	2	assisted in the main part of the experiment	assisted in the main part of the experiment	Performed the experiments	Investigation	YES
5440764	28588604	MW	2	mainly assisted in the cultivation of experimental samples	mainly assisted in the cultivation of experimental samples	Performed the experiments	Investigation	YES
5440764	28588604	MX	2	assisted in the main part of the experiment	assisted in the main part of the experiment	Performed the experiments	Investigation	YES
5440764	28588604	QS	2	provides experimental guidance	provides experimental guidance	-	Supervision	YES
5440764	28588604	SL	2	assisted in the main part of the experiment	assisted in the main part of the experiment	Performed the experiments	Investigation	YES
5440764	28588604	SY	2	is responsible for the whole process of experimenting and writing the paper	is responsible for the whole process of experimenting and writing the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5440764	28588604	XT	2	assisted in the main part of the experiment	assisted in the main part of the experiment	Performed the experiments	Investigation	YES
4398443	25876057	AH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398443	25876057	AH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398443	25876057	AH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398443	25876057	AH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398443	25876057	AH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398443	25876057	AO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398443	25876057	AO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398443	25876057	AO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398443	25876057	AO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398443	25876057	AO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398443	25876057	HO	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4398443	25876057	HO	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4398443	25876057	HU	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4398443	25876057	JM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4398443	25876057	JM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4398443	25876057	JM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398443	25876057	KN	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4398443	25876057	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398443	25876057	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4398443	25876057	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4398443	25876057	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398443	25876057	TS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398443	25876057	TS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398443	25876057	TS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398443	25876057	TS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398443	25876057	TS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398443	25876057	WN	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4398443	25876057	YM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4398443	25876057	YM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4398443	25876057	YM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5011828	27595709	ATHU	2	conceived and designed the study|performed the analyses|wrote the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5011828	27595709	ATHU	2	conceived and designed the study|performed the analyses|wrote the manuscript	performed the analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5011828	27595709	ATHU	2	conceived and designed the study|performed the analyses|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5011828	27595709	All authors	2	have agreed on the content of the manuscript	have agreed on the content of the manuscript	-	-	NO
5011828	27595709	DJAS	2	performed the analyses	performed the analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5011828	27595709	DMB	2	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5011828	27595709	JFG	2	conceived and designed the study|provided the genotypes	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5011828	27595709	JFG	2	conceived and designed the study|provided the genotypes	provided the genotypes	Performed the experiments	Investigation	YES
5011828	27595709	JS	2	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5011828	27595709	MM	2	performed the analyses|wrote the manuscript	performed the analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5011828	27595709	MM	2	performed the analyses|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5011828	27595709	MVGBS	2	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5011828	27595709	PAM	2	conceived and designed the study|provided the genotypes	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5011828	27595709	PAM	2	conceived and designed the study|provided the genotypes	provided the genotypes	Performed the experiments	Investigation	YES
5011828	27595709	RF	2	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5011828	27595709	SAB	2	performed the analyses	performed the analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5011828	27595709	YTU	2	performed the analyses|wrote the manuscript	performed the analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5011828	27595709	YTU	2	performed the analyses|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6410001	30769846	Chunhong Gao	PLoS52	helped perform the analysis with constructive discussions	helped perform the analysis with constructive discussions	Performed the experiments	Investigation	YES
6410001	30769846	Chunsheng Gao	PLoS52	performed manuscript review	performed manuscript review	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
6410001	30769846	G.Y.	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
6410001	30769846	L.C.	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
6410001	30769846	Lu Chen	PLoS52	performed the data analyses and wrote the manuscript	performed the data analyses and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6410001	30769846	M.Y.	PLoS52	performed manuscript review	performed manuscript review	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
6410001	30769846	W.G.	PLoS52	provided assistance for data acquisition and statistical analysis	provided assistance for data acquisition and statistical analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
6410001	30769846	X.C.	PLoS52	helped perform the analysis with constructive discussions	helped perform the analysis with constructive discussions	Performed the experiments	Investigation	YES
6410001	30769846	Y.W.	PLoS52	helped perform the analysis with constructive discussions	helped perform the analysis with constructive discussions	Performed the experiments	Investigation	YES
6410001	30769846	Y.Y.	PLoS52	provided assistance for data acquisition and statistical analysis	provided assistance for data acquisition and statistical analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
6410001	30769846	Z.L.	PLoS52	provided assistance for data acquisition and statistical analysis	provided assistance for data acquisition and statistical analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5378751	27289370	AERB	2	participated in the design of the study and contributed to the writing of the manuscript	participated in the design of the study and contributed to the writing of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5378751	27289370	CM	2	participated in the design of the study and contributed to the writing of the manuscript	participated in the design of the study and contributed to the writing of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5378751	27289370	HdV	2	participated in the design of the study and contributed to the writing of the manuscript	participated in the design of the study and contributed to the writing of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5378751	27289370	LEA	2	participated in the design of the study and contributed to the writing of the manuscript	participated in the design of the study and contributed to the writing of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5378751	27289370	SME	2	participated in the design of the study, conducted the analysis and drafted the manuscript	participated in the design of the study, conducted the analysis and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5378751	27289370	TM-A	2	participated in the design of the study and contributed to the writing of the manuscript	participated in the design of the study and contributed to the writing of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5440801	28588605	All authors	2	wrote and edited the manuscript	wrote and edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5440801	28588605	HZ	2	performed the experimental work|performed the data analysis	performed the experimental work	Performed the experiments	Investigation	YES
5440801	28588605	HZ	2	performed the experimental work|performed the data analysis	performed the data analysis	Analyzed the data	Formal analysis	YES
5440801	28588605	LB	2	performed the data analysis	performed the data analysis	Analyzed the data	Formal analysis	YES
5440801	28588605	LD	2	designed the experiments|performed the data analysis|supervised the research and manuscript preparation	designed the experiments	Conceived and designed the experiments	Methodology	YES
5440801	28588605	LD	2	designed the experiments|performed the data analysis|supervised the research and manuscript preparation	performed the data analysis	Analyzed the data	Formal analysis	YES
5440801	28588605	LD	2	designed the experiments|performed the data analysis|supervised the research and manuscript preparation	supervised the research and manuscript preparation	Wrote the paper	Supervision|Writing - Original Draft	YES
5440801	28588605	LP	2	designed the experiments|performed the experimental work|performed the data analysis	designed the experiments	Conceived and designed the experiments	Methodology	YES
5440801	28588605	LP	2	designed the experiments|performed the experimental work|performed the data analysis	performed the experimental work	Performed the experiments	Investigation	YES
5440801	28588605	LP	2	designed the experiments|performed the experimental work|performed the data analysis	performed the data analysis	Analyzed the data	Formal analysis	YES
5440801	28588605	QY	2	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
4411448	25954750	Guo Wei	2	contributed equally to this work	contributed equally to this work	-	-	NO
4411448	25954750	Jialin Duan	2	contributed equally to this work	contributed equally to this work	-	-	NO
4411448	25954750	Yan Cheng	2	contributed equally to this work	contributed equally to this work	-	-	NO
4411448	25954750	Ying Yin	2	contributed equally to this work	contributed equally to this work	-	-	NO
4411448	25954750	Yue Guan	2	contributed equally to this work	contributed equally to this work	-	-	NO
4398444	25874989	KN	PLoS5	Conceived and designed the experiments|Wrote the paper|Discussed the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398444	25874989	KN	PLoS5	Conceived and designed the experiments|Wrote the paper|Discussed the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398444	25874989	KN	PLoS5	Conceived and designed the experiments|Wrote the paper|Discussed the paper	Discussed the paper	-	-	NO
4398444	25874989	MK	PLoS5	Discussed the paper	Discussed the paper	-	-	NO
4398444	25874989	NF	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398444	25874989	NO	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4398444	25874989	NO	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4398444	25874989	NS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4398444	25874989	NS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4398444	25874989	NT	PLoS5	Discussed the paper	Discussed the paper	-	-	NO
4398444	25874989	TK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398444	25874989	TO	PLoS5	Conceived and designed the experiments|Wrote the paper|Discussed the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398444	25874989	TO	PLoS5	Conceived and designed the experiments|Wrote the paper|Discussed the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398444	25874989	TO	PLoS5	Conceived and designed the experiments|Wrote the paper|Discussed the paper	Discussed the paper	-	-	NO
4398444	25874989	YH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Discussed the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398444	25874989	YH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Discussed the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398444	25874989	YH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Discussed the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398444	25874989	YH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Discussed the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398444	25874989	YH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Discussed the paper	Discussed the paper	-	-	NO
4398444	25874989	YS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4398444	25874989	YS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398444	25874989	YU	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4398444	25874989	YU	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5011893	27595750	ATB	2	performed the experiments and analysis, and wrote the main manuscript	performed the experiments and analysis, and wrote the main manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5011893	27595750	All authors	2	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5011893	27595750	NLB	2	contributed to analysis and prepared fig	contributed to analysis and prepared fig	-	Visualization	YES
6410004	30717144	C.M.	CRediT	Writing-original draft preparation	Writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
6410004	30717144	D.P.	CRediT	Formal analysis|Investigation	Formal analysis	Analyzed the data	Formal analysis	YES
6410004	30717144	D.P.	CRediT	Formal analysis|Investigation	Investigation	Performed the experiments	Investigation	YES
6410004	30717144	F.M.	CRediT	Investigation|Writing-original draft preparation	Investigation	Performed the experiments	Investigation	YES
6410004	30717144	F.M.	CRediT	Investigation|Writing-original draft preparation	Writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
6410004	30717144	F.R.	CRediT	Investigation|Visualization	Investigation	Performed the experiments	Investigation	YES
6410004	30717144	F.R.	CRediT	Investigation|Visualization	Visualization	Analyzed the data	Visualization	YES
6410004	30717144	M.C.	CRediT	Conceptualization|Methodology	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6410004	30717144	M.C.	CRediT	Conceptualization|Methodology	Methodology	Performed the experiments	Methodology	YES
6410004	30717144	M.R.	CRediT	Methodology	Methodology	Performed the experiments	Methodology	YES
6410004	30717144	P.M.	CRediT	Formal analysis|Investigation|Visualization	Formal analysis	Analyzed the data	Formal analysis	YES
6410004	30717144	P.M.	CRediT	Formal analysis|Investigation|Visualization	Investigation	Performed the experiments	Investigation	YES
6410004	30717144	P.M.	CRediT	Formal analysis|Investigation|Visualization	Visualization	Analyzed the data	Visualization	YES
6410004	30717144	S.P.	CRediT	Conceptualization|Methodology|Writing-original draft preparation	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6410004	30717144	S.P.	CRediT	Conceptualization|Methodology|Writing-original draft preparation	Methodology	Performed the experiments	Methodology	YES
6410004	30717144	S.P.	CRediT	Conceptualization|Methodology|Writing-original draft preparation	Writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
5378753	27900502	All authors	2	provided feedback on drafts of the manuscript and approved of the final version	provided feedback on drafts of the manuscript and approved of the final version	Wrote the paper	Writing - Original Draft	YES
5378753	27900502	CK	2	conceived the review, including developing the research question, outcomes of interest, and inclusion criteria|conducted the literature search and screening|provided feedback on the analysis	conceived the review, including developing the research question, outcomes of interest, and inclusion criteria	Conceived and designed the experiments	Conceptualization	YES
5378753	27900502	CK	2	conceived the review, including developing the research question, outcomes of interest, and inclusion criteria|conducted the literature search and screening|provided feedback on the analysis	conducted the literature search and screening	Performed the experiments	Formal analysis|Investigation	YES
5378753	27900502	CK	2	conceived the review, including developing the research question, outcomes of interest, and inclusion criteria|conducted the literature search and screening|provided feedback on the analysis	provided feedback on the analysis	-	-	NO
5378753	27900502	FK	2	conceived the review, including developing the research question, outcomes of interest, and inclusion criteria|conducted the literature search and screening|conducted the data abstraction and data analysis|wrote the first draft of this manuscript	conceived the review, including developing the research question, outcomes of interest, and inclusion criteria	Conceived and designed the experiments	Conceptualization	YES
5378753	27900502	FK	2	conceived the review, including developing the research question, outcomes of interest, and inclusion criteria|conducted the literature search and screening|conducted the data abstraction and data analysis|wrote the first draft of this manuscript	conducted the literature search and screening	Performed the experiments	Formal analysis|Investigation	YES
5378753	27900502	FK	2	conceived the review, including developing the research question, outcomes of interest, and inclusion criteria|conducted the literature search and screening|conducted the data abstraction and data analysis|wrote the first draft of this manuscript	conducted the data abstraction and data analysis	Analyzed the data	Formal analysis	YES
5378753	27900502	FK	2	conceived the review, including developing the research question, outcomes of interest, and inclusion criteria|conducted the literature search and screening|conducted the data abstraction and data analysis|wrote the first draft of this manuscript	wrote the first draft of this manuscript	Wrote the paper	Writing - Original Draft	YES
5378753	27900502	KO	2	conceived the review, including developing the research question, outcomes of interest, and inclusion criteria	conceived the review, including developing the research question, outcomes of interest, and inclusion criteria	Conceived and designed the experiments	Conceptualization	YES
5378753	27900502	KR	2	provided feedback on the analysis	provided feedback on the analysis	-	-	NO
5378753	27900502	RB	2	conceived the review, including developing the research question, outcomes of interest, and inclusion criteria	conceived the review, including developing the research question, outcomes of interest, and inclusion criteria	Conceived and designed the experiments	Conceptualization	YES
5378753	27900502	SD	2	conducted the literature search and screening	conducted the literature search and screening	Performed the experiments	Formal analysis|Investigation	YES
5378753	27900502	VF	2	conducted the literature search and screening	conducted the literature search and screening	Performed the experiments	Formal analysis|Investigation	YES
4398445	25874859	AL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Principal investigators	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398445	25874859	AL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Principal investigators	Performed the experiments	Performed the experiments	Investigation	YES
4398445	25874859	AL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Principal investigators	Analyzed the data	Analyzed the data	Formal analysis	YES
4398445	25874859	AL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Principal investigators	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398445	25874859	AL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Principal investigators	Principal investigators	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
4398445	25874859	CRM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Principal investigators	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398445	25874859	CRM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Principal investigators	Analyzed the data	Analyzed the data	Formal analysis	YES
4398445	25874859	CRM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Principal investigators	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398445	25874859	CRM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Principal investigators	Principal investigators	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
4398445	25874859	DJS	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398445	25874859	ECM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398445	25874859	ECM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398445	25874859	ECM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398445	25874859	ECM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398445	25874859	JG	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4398445	25874859	JG	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4398445	25874859	SV	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4398445	25874859	SV	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5441063	28588588	CB	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5441063	28588588	FR	2	supervised the project|wrote the manuscript	supervised the project	-	Supervision	YES
5441063	28588588	FR	2	supervised the project|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5011910	27595771	AHS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
5011910	27595771	AHS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5011910	27595771	AHS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5011910	27595771	CGG	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
5011910	27595771	CGG	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5011910	27595771	CGG	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5011910	27595771	JD	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools and acquired funding|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5011910	27595771	JD	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools and acquired funding|Wrote the paper	Contributed reagents/materials/analysis tools and acquired funding	Contributed reagents/materials/analysis tools	Funding acquisition|Resources	YES
5011910	27595771	JD	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools and acquired funding|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6410025	30769938	A.J.M.V.	CRediT	writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6410025	30769938	B.F.O.N.	CRediT	Writing--original draft preparation	Writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6410025	30769938	M.P.	CRediT	Writing--original draft preparation|writing--review and editing	Writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6410025	30769938	M.P.	CRediT	Writing--original draft preparation|writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6410025	30769938	N.A.M.P.	CRediT	Writing--original draft preparation	Writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6410025	30769938	T.M.V.D.P.e.M.	CRediT	writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
4398446	25874957	CC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398446	25874957	CZ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398446	25874957	CZ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398446	25874957	CZ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398446	25874957	CZ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398446	25874957	HC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4398446	25874957	HC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398446	25874957	HL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398446	25874957	HL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398446	25874957	HL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398446	25874957	HL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398446	25874957	JH	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398446	25874957	ZW	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4398446	25874957	ZW	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5422450	27613646	DNB	2	designed the intervention package and conceptualized the study, designed the protocol, coordinated and managed all the aspects of study procedures, reviewed study data, analyzed and interpreted the data, and drafted the manuscript	designed the intervention package and conceptualized the study, designed the protocol, coordinated and managed all the aspects of study procedures, reviewed study data, analyzed and interpreted the data, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Data curation|Formal analysis|Investigation|Methodology|Project administration|Writing - Original Draft|Writing - Review & Editing	YES
5422450	27613646	TL	2	participated in designing the protocol, designed the study, reviewed study data, and reviewed and edited the final manuscript	participated in designing the protocol, designed the study, reviewed study data, and reviewed and edited the final manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5441111	28588593	CS	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
5441111	28588593	CZ	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
5441111	28588593	HZ	PLoS52	contributed new reagents or analytic tools	contributed new reagents or analytic tools	Contributed reagents/materials/analysis tools	Resources	YES
5441111	28588593	JM	PLoS52	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5441111	28588593	KC	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
5441111	28588593	MY	PLoS52	contributed new reagents or analytic tools	contributed new reagents or analytic tools	Contributed reagents/materials/analysis tools	Resources	YES
5441111	28588593	QZ	PLoS52	performed research|analyzed data	performed research	Performed the experiments	Investigation	YES
5441111	28588593	QZ	PLoS52	performed research|analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5441111	28588593	SC	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5441111	28588593	SD	PLoS52	designed research|performed research|analyzed data|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
5441111	28588593	SD	PLoS52	designed research|performed research|analyzed data|wrote the paper	performed research	Performed the experiments	Investigation	YES
5441111	28588593	SD	PLoS52	designed research|performed research|analyzed data|wrote the paper	analyzed data	Analyzed the data	Formal analysis	YES
5441111	28588593	SD	PLoS52	designed research|performed research|analyzed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5441111	28588593	SW	PLoS52	designed research|performed research|analyzed data|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
5441111	28588593	SW	PLoS52	designed research|performed research|analyzed data|wrote the paper	performed research	Performed the experiments	Investigation	YES
5441111	28588593	SW	PLoS52	designed research|performed research|analyzed data|wrote the paper	analyzed data	Analyzed the data	Formal analysis	YES
5441111	28588593	SW	PLoS52	designed research|performed research|analyzed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5441111	28588593	WM	PLoS52	contributed new reagents or analytic tools	contributed new reagents or analytic tools	Contributed reagents/materials/analysis tools	Resources	YES
5441111	28588593	YB	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
5441111	28588593	ZX	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
5011921	27601031	AA	2	performed the computational analyses	performed the computational analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5011921	27601031	All authors	2	contributed with the revision of the work	contributed with the revision of the work	Wrote the paper	Writing - Review & Editing	YES
5011921	27601031	CV-L	2	participated in the characterization of the strains	participated in the characterization of the strains	Performed the experiments	Investigation	YES
5011921	27601031	EM	2	contributed with interpretation and discussion of the results	contributed with interpretation and discussion of the results	Analyzed the data	Formal analysis	YES
5011921	27601031	ES	2	participated in the characterization of the strains	participated in the characterization of the strains	Performed the experiments	Investigation	YES
5011921	27601031	GM-B	2	performed the proteomic analyses	performed the proteomic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5011921	27601031	HP	2	designed the study|performed the computational analyses|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5011921	27601031	HP	2	designed the study|performed the computational analyses|wrote the manuscript	performed the computational analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5011921	27601031	HP	2	designed the study|performed the computational analyses|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5011921	27601031	JM	2	designed the study|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5011921	27601031	JM	2	designed the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5011921	27601031	LG	2	contributed with interpretation and discussion of the results	contributed with interpretation and discussion of the results	Analyzed the data	Formal analysis	YES
5011921	27601031	RD	2	participated in the characterization of the strains	participated in the characterization of the strains	Performed the experiments	Investigation	YES
5011921	27601031	SE	2	performed the proteomic analyses	performed the proteomic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5011921	27601031	YM	2	participated in the characterization of the strains	participated in the characterization of the strains	Performed the experiments	Investigation	YES
4411451	25954747	Bin Wang	2	contributed equally to this work	contributed equally to this work	-	-	NO
4411451	25954747	Weiling Hu	2	contributed equally to this work	contributed equally to this work	-	-	NO
6410046	30791612	A.B.	2	supervised the under	supervised the under	-	Supervision	YES
6410046	30791612	E.H.C.	2	supervised the under|is the principal investigator and the main supervisor	supervised the under	-	Supervision	YES
6410046	30791612	E.H.C.	2	supervised the under|is the principal investigator and the main supervisor	is the principal investigator and the main supervisor	Conceived and designed the experiments	Conceptualization|Funding acquisition|Supervision	YES
6410046	30791612	J.S.	2	helped with the carried out experiments with technical	helped with the carried out experiments with technical	Performed the experiments	Investigation	YES
6410046	30791612	M.E.K.	2	carried out experiments with technical	carried out experiments with technical	Performed the experiments	Investigation	YES
4398447	25875179	HK	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398447	25875179	HK	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398447	25875179	HT	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4398447	25875179	HT	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398447	25875179	KA	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398447	25875179	KS	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4398447	25875179	MK	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398447	25875179	MO	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4398447	25875179	MO	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4398447	25875179	NM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4398447	25875179	NM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398447	25875179	RM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398447	25875179	SC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398447	25875179	SC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398447	25875179	SC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398447	25875179	SC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398447	25875179	SY	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398447	25875179	TW	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398447	25875179	TW	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398447	25875179	TY	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398447	25875179	TY	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4398447	25875179	TY	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398447	25875179	YM	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398447	25875179	YM	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5442176	28596778	AL	2	carried out metabolite analyses	carried out metabolite analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5442176	28596778	CM	2	conceived and planned research|carried out all enzymatic analyses|carried out metabolite analyses|drafted the manuscript	conceived and planned research	Conceived and designed the experiments	Conceptualization	YES
5442176	28596778	CM	2	conceived and planned research|carried out all enzymatic analyses|carried out metabolite analyses|drafted the manuscript	carried out all enzymatic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5442176	28596778	CM	2	conceived and planned research|carried out all enzymatic analyses|carried out metabolite analyses|drafted the manuscript	carried out metabolite analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5442176	28596778	CM	2	conceived and planned research|carried out all enzymatic analyses|carried out metabolite analyses|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5442176	28596778	ED	2	provided technical assistance and assisted with manuscript revision	provided technical assistance and assisted with manuscript revision	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5442176	28596778	EL	2	provided technical assistance and assisted with manuscript revision	provided technical assistance and assisted with manuscript revision	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5442176	28596778	FF	2	conceived and planned research|provided technical assistance and assisted with manuscript revision	conceived and planned research	Conceived and designed the experiments	Conceptualization	YES
5442176	28596778	FF	2	conceived and planned research|provided technical assistance and assisted with manuscript revision	provided technical assistance and assisted with manuscript revision	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5442176	28596778	JF	2	carried out metabolite analyses	carried out metabolite analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5442176	28596778	KF	2	conceived and planned research|drafted the manuscript	conceived and planned research	Conceived and designed the experiments	Conceptualization	YES
5442176	28596778	KF	2	conceived and planned research|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5442176	28596778	LC	2	assisted with statistical analyses	assisted with statistical analyses	Analyzed the data	Formal analysis	YES
5011931	27595578	EN	2	guided software feature enrichment|additionally helped revise computational experiments|helped draft the manuscript	guided software feature enrichment	Contributed reagents/materials/analysis tools	Software|Supervision	YES
5011931	27595578	EN	2	guided software feature enrichment|additionally helped revise computational experiments|helped draft the manuscript	additionally helped revise computational experiments	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
5011931	27595578	EN	2	guided software feature enrichment|additionally helped revise computational experiments|helped draft the manuscript	helped draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5011931	27595578	MW	2	performed the h3 wet lab protocol	performed the h3 wet lab protocol	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5011931	27595578	SM	2	developed and performed the h7 wet lab protocol|provided help with the initial requirements of the project	developed and performed the h7 wet lab protocol	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5011931	27595578	SM	2	developed and performed the h7 wet lab protocol|provided help with the initial requirements of the project	provided help with the initial requirements of the project	-	-	NO
5011931	27595578	SSS	2	developed the software, wrote the manuscript, and carried out the computational analyses|curated the influenza datasets	developed the software, wrote the manuscript, and carried out the computational analyses	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Software|Writing - Original Draft	YES
5011931	27595578	SSS	2	developed the software, wrote the manuscript, and carried out the computational analyses|curated the influenza datasets	curated the influenza datasets	Analyzed the data	Data curation	YES
6410052	30813270	J.S.	2	participated in the conceptualization, data analysis, and reviewing and editing of the manuscript, and acquired the funding	participated in the conceptualization, data analysis, and reviewing and editing of the manuscript, and acquired the funding	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Funding acquisition|Writing - Review & Editing	YES
6410052	30813270	M.Q.	2	as corresponding author, acquired the funding, participated in the study conceptualization, data analysis, and reviewing and editing of the manuscript, and finalized this manuscript	as corresponding author, acquired the funding, participated in the study conceptualization, data analysis, and reviewing and editing of the manuscript, and finalized this manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Funding acquisition|Investigation|Writing - Review & Editing	YES
6410052	30813270	R.Z.	2	participated in the experiment, including the investigation, methodology, data co-relation, formal analysis of data, research administration, and drafting of the original manuscript	participated in the experiment, including the investigation, methodology, data co-relation, formal analysis of data, research administration, and drafting of the original manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
6410052	30813270	Y.L.	2	participated in research administration and revising the manuscript	participated in research administration and revising the manuscript	Wrote the paper	Writing - Review & Editing	YES
6410052	30813270	Y.Q.	2	participated in research administration and revising the manuscript	participated in research administration and revising the manuscript	Wrote the paper	Writing - Review & Editing	YES
6410052	30813270	Z.C.	2	participated in research administration and revising the manuscript	participated in research administration and revising the manuscript	Wrote the paper	Writing - Review & Editing	YES
6410052	30813270	Z.K.	2	participated in research administration and revising the manuscript	participated in research administration and revising the manuscript	Wrote the paper	Writing - Review & Editing	YES
4398448	25875361	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398448	25875361	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398448	25875361	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398448	25875361	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398448	25875361	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398448	25875361	KR	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398448	25875361	KR	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398448	25875361	KR	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398448	25875361	KR	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398448	25875361	LB	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398448	25875361	LB	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398448	25875361	LB	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398448	25875361	LB	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6410054	30700021	All authors	2	contributed to substantial enhancement of the manuscript	contributed to substantial enhancement of the manuscript	-	-	NO
6410054	30700021	M.W.	2	revise the manuscript	revise the manuscript	Wrote the paper	Writing - Review & Editing	YES
6410054	30700021	S.H.	2	revise the manuscript	revise the manuscript	Wrote the paper	Writing - Review & Editing	YES
6410054	30700021	W.-E.Y.	2	revise the manuscript	revise the manuscript	Wrote the paper	Writing - Review & Editing	YES
5442205	28596777	All authors	2	have contributed to, seen and approved the manuscript	have contributed to, seen and approved the manuscript	-	-	NO
5442205	28596777	CW	2	defined the research theme and co-designed experiments, and discussed analyses	defined the research theme and co-designed experiments, and discussed analyses	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5442205	28596777	DM	2	designed the methods, experiments and wrote the manuscript	designed the methods, experiments and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5442205	28596777	DS	2	carried out the experiments and analyzed the data	carried out the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5442205	28596777	HD	2	co-worked on laboratory analysis	co-worked on laboratory analysis	Performed the experiments	Investigation	YES
5442205	28596777	HQ	2	co-worked on laboratory analysis	co-worked on laboratory analysis	Performed the experiments	Investigation	YES
5442205	28596777	JH	2	contributed the zn element analysis	contributed the zn element analysis	-	-	NO
5442205	28596777	TG	2	defined the research theme and co-designed experiments, and discussed analyses	defined the research theme and co-designed experiments, and discussed analyses	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5442205	28596777	XH	2	contributed the zn element analysis	contributed the zn element analysis	-	-	NO
5442205	28596777	YX	2	co-worked on associated data collection and their interpretation	co-worked on associated data collection and their interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5011991	27595608	ABP	2	provided comments and discussion	provided comments and discussion	-	-	NO
5011991	27595608	AMVB	2	provided comments and discussion	provided comments and discussion	-	-	NO
5011991	27595608	DKH	2	provided comments and discussion|constructed the illumina miseq library and performed an initial sequence assembly	provided comments and discussion	-	-	NO
5011991	27595608	DKH	2	provided comments and discussion|constructed the illumina miseq library and performed an initial sequence assembly	constructed the illumina miseq library and performed an initial sequence assembly	Performed the experiments	Investigation	YES
5011991	27595608	DRD	2	provided comments and discussion	provided comments and discussion	-	-	NO
5011991	27595608	IAZ	2	provided comments and discussion|supervised the study	provided comments and discussion	-	-	NO
5011991	27595608	IAZ	2	provided comments and discussion|supervised the study	supervised the study	-	Supervision	YES
5011991	27595608	VCB	2	provided comments and discussion	provided comments and discussion	-	-	NO
5011991	27595608	WSP	2	performed all subsequent computational analyses, molecular experiments, and data analyses and prepared the manuscript with comments from all authors	performed all subsequent computational analyses, molecular experiments, and data analyses and prepared the manuscript with comments from all authors	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4398449	25874769	EK	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4398449	25874769	HH	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398449	25874769	HY	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398449	25874769	JO	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398449	25874769	K. Obata	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398449	25874769	K. Okumoto	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398449	25874769	MF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398449	25874769	MF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398449	25874769	MF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398449	25874769	MF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398449	25874769	MM	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398449	25874769	MS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4398449	25874769	MS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398449	25874769	SM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398449	25874769	SN	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398449	25874769	ST-K	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398449	25874769	ST-K	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398449	25874769	TM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398449	25874769	TS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398449	25874769	TS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398449	25874769	TU	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398449	25874769	YK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4398449	25874769	YK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398449	25874769	YY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398449	25874769	YY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398449	25874769	YY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398449	25874769	YY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5909400	24034492	AZ	1	Execution of search strategy & screening	Execution of search strategy & screening	Performed the experiments	Investigation	YES
5909400	24034492	GD	1	Execution of search strategy & screening|Risk of bias assessment & acquisition of data|Analysis & interpretation of data	Execution of search strategy & screening	Performed the experiments	Investigation	YES
5909400	24034492	GD	1	Execution of search strategy & screening|Risk of bias assessment & acquisition of data|Analysis & interpretation of data	Risk of bias assessment & acquisition of data	Performed the experiments	Investigation	YES
5909400	24034492	GD	1	Execution of search strategy & screening|Risk of bias assessment & acquisition of data|Analysis & interpretation of data	Analysis & interpretation of data	Analyzed the data	Formal analysis	YES
5909400	24034492	GM	1	Risk of bias assessment & acquisition of data	Risk of bias assessment & acquisition of data	Performed the experiments	Investigation	YES
5909400	24034492	HH	1	Execution of search strategy & screening|Risk of bias assessment & acquisition of data	Execution of search strategy & screening	Performed the experiments	Investigation	YES
5909400	24034492	HH	1	Execution of search strategy & screening|Risk of bias assessment & acquisition of data	Risk of bias assessment & acquisition of data	Performed the experiments	Investigation	YES
5909400	24034492	JP	1	Execution of search strategy & screening	Execution of search strategy & screening	Performed the experiments	Investigation	YES
5909400	24034492	JT	1	Execution of search strategy & screening	Execution of search strategy & screening	Performed the experiments	Investigation	YES
5909400	24034492	JVT	1	Analysis & interpretation of data	Analysis & interpretation of data	Analyzed the data	Formal analysis	YES
5909400	24034492	LB	1	Execution of search strategy & screening	Execution of search strategy & screening	Performed the experiments	Investigation	YES
5909400	24034492	LS	1	Risk of bias assessment & acquisition of data	Risk of bias assessment & acquisition of data	Performed the experiments	Investigation	YES
5909400	24034492	MC	1	Risk of bias assessment & acquisition of data	Risk of bias assessment & acquisition of data	Performed the experiments	Investigation	YES
5909400	24034492	MM	1	Execution of search strategy & screening|Risk of bias assessment & acquisition of data	Execution of search strategy & screening	Performed the experiments	Investigation	YES
5909400	24034492	MM	1	Execution of search strategy & screening|Risk of bias assessment & acquisition of data	Risk of bias assessment & acquisition of data	Performed the experiments	Investigation	YES
5909400	24034492	RCH	1	Execution of search strategy & screening|Risk of bias assessment & acquisition of data	Execution of search strategy & screening	Performed the experiments	Investigation	YES
5909400	24034492	RCH	1	Execution of search strategy & screening|Risk of bias assessment & acquisition of data	Risk of bias assessment & acquisition of data	Performed the experiments	Investigation	YES
5909400	24034492	RH	1	Execution of search strategy & screening	Execution of search strategy & screening	Performed the experiments	Investigation	YES
5909400	24034492	RS	1	Risk of bias assessment & acquisition of data	Risk of bias assessment & acquisition of data	Performed the experiments	Investigation	YES
5909400	24034492	SE	1	Execution of search strategy & screening	Execution of search strategy & screening	Performed the experiments	Investigation	YES
5909400	24034492	SM	1	Execution of search strategy & screening	Execution of search strategy & screening	Performed the experiments	Investigation	YES
5909400	24034492	YC	1	Execution of search strategy & screening	Execution of search strategy & screening	Performed the experiments	Investigation	YES
4398450	25874864	CX	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398450	25874864	FH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398450	25874864	FH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398450	25874864	FH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398450	25874864	FH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398450	25874864	HL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398450	25874864	HL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398450	25874864	HL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398450	25874864	LZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398450	25874864	SL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4398450	25874864	SL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398450	25874864	WD	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4398450	25874864	WD	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398450	25874864	XL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4398450	25874864	XL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398450	25874864	YL	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398450	25874864	YL	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5442206	28596774	FC	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5442206	28596774	GC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5442206	28596774	GC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
5442206	28596774	GC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5442206	28596774	GC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5442206	28596774	GC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5442206	28596774	IR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5442206	28596774	IR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5442206	28596774	IR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5442206	28596774	IR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5442206	28596774	PP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5442206	28596774	PP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5442206	28596774	PP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5442206	28596774	SA	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
5442206	28596774	SA	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5012078	27600936	LB	2	performed the analysis on the rated of evolution of the de transcripts	performed the analysis on the rated of evolution of the de transcripts	Performed the experiments	Investigation	YES
5012078	27600936	MES	2	conceived the study, designed the research and wrote the manuscript	conceived the study, designed the research and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
5012078	27600936	NB	2	helped with the macrops with the	helped with the macrops with the	-	-	NO
5012078	27600936	WS	2	conceived the study, designed the research and wrote the manuscript	conceived the study, designed the research and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
5012078	27600936	ZM	2	performed the clustering analyses of the gene expression data	performed the clustering analyses of the gene expression data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4398451	25875091	AR	PLoS5	Performed the experiments|Wrote the paper|Interacted with the patients as part of their routine outpatient clinical practice	Performed the experiments	Performed the experiments	Investigation	YES
4398451	25875091	AR	PLoS5	Performed the experiments|Wrote the paper|Interacted with the patients as part of their routine outpatient clinical practice	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398451	25875091	AR	PLoS5	Performed the experiments|Wrote the paper|Interacted with the patients as part of their routine outpatient clinical practice	Interacted with the patients as part of their routine outpatient clinical practice	-	-	NO
4398451	25875091	CG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Interacted with the patients as part of their routine outpatient clinical practice	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398451	25875091	CG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Interacted with the patients as part of their routine outpatient clinical practice	Performed the experiments	Performed the experiments	Investigation	YES
4398451	25875091	CG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Interacted with the patients as part of their routine outpatient clinical practice	Analyzed the data	Analyzed the data	Formal analysis	YES
4398451	25875091	CG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Interacted with the patients as part of their routine outpatient clinical practice	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398451	25875091	CG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Interacted with the patients as part of their routine outpatient clinical practice	Interacted with the patients as part of their routine outpatient clinical practice	-	-	NO
4398451	25875091	DC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398451	25875091	DC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398451	25875091	DC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398451	25875091	DC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398451	25875091	DC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398451	25875091	DM	PLoS5	Performed the experiments|Interacted with the patients as part of their routine outpatient clinical practice	Performed the experiments	Performed the experiments	Investigation	YES
4398451	25875091	DM	PLoS5	Performed the experiments|Interacted with the patients as part of their routine outpatient clinical practice	Interacted with the patients as part of their routine outpatient clinical practice	-	-	NO
4398451	25875091	EC	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398451	25875091	EC	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398451	25875091	GR	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398451	25875091	GR	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398451	25875091	LF	PLoS5	Performed the experiments|Interacted with the patients as part of their routine outpatient clinical practice	Performed the experiments	Performed the experiments	Investigation	YES
4398451	25875091	LF	PLoS5	Performed the experiments|Interacted with the patients as part of their routine outpatient clinical practice	Interacted with the patients as part of their routine outpatient clinical practice	-	-	NO
4398451	25875091	LM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398451	25875091	MG	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398451	25875091	MG	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398451	25875091	NC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4398451	25875091	NC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398451	25875091	PM	PLoS5	Performed the experiments|Interacted with the patients as part of their routine outpatient clinical practice	Performed the experiments	Performed the experiments	Investigation	YES
4398451	25875091	PM	PLoS5	Performed the experiments|Interacted with the patients as part of their routine outpatient clinical practice	Interacted with the patients as part of their routine outpatient clinical practice	-	-	NO
4398451	25875091	SL	PLoS5	Performed the experiments|Interacted with the patients as part of their routine outpatient clinical practice	Performed the experiments	Performed the experiments	Investigation	YES
4398451	25875091	SL	PLoS5	Performed the experiments|Interacted with the patients as part of their routine outpatient clinical practice	Interacted with the patients as part of their routine outpatient clinical practice	-	-	NO
4398451	25875091	VC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4398451	25875091	VC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
6410067	30691225	E.S.L.	2	contributed to the conduct of the experiments, data analyses, and the preparation of the manuscript	contributed to the conduct of the experiments, data analyses, and the preparation of the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft	YES
6410067	30691225	H.L.	2	contributed equally to this work as first authors|contributed to the conduct of the experiments, data analyses, and the preparation of the manuscript	contributed equally to this work as first authors	-	-	NO
6410067	30691225	H.L.	2	contributed equally to this work as first authors|contributed to the conduct of the experiments, data analyses, and the preparation of the manuscript	contributed to the conduct of the experiments, data analyses, and the preparation of the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft	YES
6410067	30691225	H.P.	2	contributed equally to this work as first authors|contributed to the conduct of the experiments, data analyses, and the preparation of the manuscript	contributed equally to this work as first authors	-	-	NO
6410067	30691225	H.P.	2	contributed equally to this work as first authors|contributed to the conduct of the experiments, data analyses, and the preparation of the manuscript	contributed to the conduct of the experiments, data analyses, and the preparation of the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft	YES
6410067	30691225	H.S.Y.	2	contributed to the conduct of the experiments, data analyses, and the preparation of the manuscript	contributed to the conduct of the experiments, data analyses, and the preparation of the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft	YES
6410067	30691225	K.N.	2	contributed to the conduct of the experiments, data analyses, and the preparation of the manuscript	contributed to the conduct of the experiments, data analyses, and the preparation of the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft	YES
6410067	30691225	K.T.O.	2	contributed to the conduct of the experiments, data analyses, and the preparation of the manuscript	contributed to the conduct of the experiments, data analyses, and the preparation of the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft	YES
4398452	25875283	BB	PLoS5	Performed the experiments|Trained subjects	Performed the experiments	Performed the experiments	Investigation	YES
4398452	25875283	BB	PLoS5	Performed the experiments|Trained subjects	Trained subjects	-	-	NO
4398452	25875283	DS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398452	25875283	DS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398452	25875283	DS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398452	25875283	DS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398452	25875283	EH	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398452	25875283	EH	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398452	25875283	NK	PLoS5	Performed the experiments|Trained subjects|Analyzed experimental artifacts	Performed the experiments	Performed the experiments	Investigation	YES
4398452	25875283	NK	PLoS5	Performed the experiments|Trained subjects|Analyzed experimental artifacts	Trained subjects	-	-	NO
4398452	25875283	NK	PLoS5	Performed the experiments|Trained subjects|Analyzed experimental artifacts	Analyzed experimental artifacts	Analyzed the data	Formal analysis	YES
4398452	25875283	TC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398452	25875283	TC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398452	25875283	TC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3531330	23273267	A. Tiam	2	conceived of the study and participated in its organization and coordination	conceived of the study and participated in its organization and coordination	Conceived and designed the experiments	Conceptualization|Project administration	YES
3531330	23273267	All authors	2	contributed to the interpretation of data, manuscript revisions, and read and approved the final manuscript	contributed to the interpretation of data, manuscript revisions, and read and approved the final manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
3531330	23273267	B. Montaung	2	contributed to the acquisition of data	contributed to the acquisition of data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
3531330	23273267	C. Luo	2	conceived of the study and participated in its organization and coordination	conceived of the study and participated in its organization and coordination	Conceived and designed the experiments	Conceptualization|Project administration	YES
3531330	23273267	C. Lure	2	conceived of the study and participated in its organization and coordination	conceived of the study and participated in its organization and coordination	Conceived and designed the experiments	Conceptualization|Project administration	YES
3531330	23273267	F. Mohai	2	contributed to the acquisition of data	contributed to the acquisition of data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
3531330	23273267	L. Dougal	2	conceived of the study and participated in its organization and coordination|contributed to the acquisition of data|analysed the data and drafted the manuscript	conceived of the study and participated in its organization and coordination	Conceived and designed the experiments	Conceptualization|Project administration	YES
3531330	23273267	L. Dougal	2	conceived of the study and participated in its organization and coordination|contributed to the acquisition of data|analysed the data and drafted the manuscript	contributed to the acquisition of data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
3531330	23273267	L. Dougal	2	conceived of the study and participated in its organization and coordination|contributed to the acquisition of data|analysed the data and drafted the manuscript	analysed the data and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3531330	23273267	M. Moteetee	2	contributed to the acquisition of data	contributed to the acquisition of data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
3531330	23273267	M. Mphale	2	contributed to the acquisition of data	contributed to the acquisition of data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
3531330	23273267	M. Reynolds	2	contributed to the acquisition of data	contributed to the acquisition of data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
3531330	23273267	N. Binkin	2	conceived of the study and participated in its organization and coordination|contributed to the acquisition of data|analysed the data and drafted the manuscript	conceived of the study and participated in its organization and coordination	Conceived and designed the experiments	Conceptualization|Project administration	YES
3531330	23273267	N. Binkin	2	conceived of the study and participated in its organization and coordination|contributed to the acquisition of data|analysed the data and drafted the manuscript	contributed to the acquisition of data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
3531330	23273267	N. Binkin	2	conceived of the study and participated in its organization and coordination|contributed to the acquisition of data|analysed the data and drafted the manuscript	analysed the data and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3531330	23273267	V. Ankrah	2	conceived of the study and participated in its organization and coordination	conceived of the study and participated in its organization and coordination	Conceived and designed the experiments	Conceptualization|Project administration	YES
5964543	20629771	All authors	2	contributed to the development of the study protocol|revised the manuscript critically and approved the final version that was submitted	contributed to the development of the study protocol	Conceived and designed the experiments	Methodology	YES
5964543	20629771	All authors	2	contributed to the development of the study protocol|revised the manuscript critically and approved the final version that was submitted	revised the manuscript critically and approved the final version that was submitted	Wrote the paper	Writing - Review & Editing	YES
5964543	20629771	C Couturier	2	managed the data collection	managed the data collection	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5964543	20629771	R Garceau	2	managed the diagnostic processes and authored this component of the methods	managed the diagnostic processes and authored this component of the methods	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5964543	20629771	Van Buynder	2	managed the data collection	managed the data collection	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5964543	20629771	W Tremblay	2	were involved in the analysis of the data and led the writing of the manuscript	were involved in the analysis of the data and led the writing of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5442208	28596776	LY	1	Conceived and designed the experiments and reviewed the manuscript	Conceived and designed the experiments and reviewed the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
5442208	28596776	XL	1	Performed the phenotyping association mapping and writing the manuscript	Performed the phenotyping association mapping and writing the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5013568	27604083	ARL	PLoS5	Transcriptome design and analysis|Contributed reagents/materials/analysis tools|Wrote the paper	Transcriptome design and analysis	Conceived and designed the experiments	-	YES
5013568	27604083	ARL	PLoS5	Transcriptome design and analysis|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5013568	27604083	ARL	PLoS5	Transcriptome design and analysis|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5013568	27604083	FJF	PLoS5	Transcriptome design and analysis|Wrote the paper	Transcriptome design and analysis	Conceived and designed the experiments	-	YES
5013568	27604083	FJF	PLoS5	Transcriptome design and analysis|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5013568	27604083	JSLP	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5013568	27604083	MWHP	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5013568	27604083	PDEMV	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5013568	27604083	PDEMV	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398453	25875203	CAC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398453	25875203	CAC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398453	25875203	CAC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398453	25875203	CAC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398453	25875203	CAC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398453	25875203	CPL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4398453	25875203	CPL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398453	25875203	JDW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398453	25875203	JDW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4398453	25875203	JDW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398453	25875203	JPS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398453	25875203	JPS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398453	25875203	JW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398453	25875203	JW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398453	25875203	MBD	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4398453	25875203	MBM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398453	25875203	MBM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398453	25875203	PLG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398453	25875203	PLG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4398453	25875203	PLG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
3535694	23336700	DGL	PLoS5	Designed the study	Designed the study	Conceived and designed the experiments	Methodology	YES
3535694	23336700	DM	PLoS5	Collected data|Analysed the data|Contributed to the writing of the manuscript	Collected data	Performed the experiments	Investigation	YES
3535694	23336700	DM	PLoS5	Collected data|Analysed the data|Contributed to the writing of the manuscript	Analysed the data	Analyzed the data	Formal analysis	YES
3535694	23336700	DM	PLoS5	Collected data|Analysed the data|Contributed to the writing of the manuscript	Contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
3535694	23336700	EEM	PLoS5	Designed the study|Analysed the data|Contributed to the writing of the manuscript	Designed the study	Conceived and designed the experiments	Methodology	YES
3535694	23336700	EEM	PLoS5	Designed the study|Analysed the data|Contributed to the writing of the manuscript	Analysed the data	Analyzed the data	Formal analysis	YES
3535694	23336700	EEM	PLoS5	Designed the study|Analysed the data|Contributed to the writing of the manuscript	Contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
3535694	23336700	ELC	PLoS5	Designed the study|Analysed the data|Contributed to the writing of the manuscript	Designed the study	Conceived and designed the experiments	Methodology	YES
3535694	23336700	ELC	PLoS5	Designed the study|Analysed the data|Contributed to the writing of the manuscript	Analysed the data	Analyzed the data	Formal analysis	YES
3535694	23336700	ELC	PLoS5	Designed the study|Analysed the data|Contributed to the writing of the manuscript	Contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
3535694	23336700	ND	PLoS5	Designed the study|Analysed the data|Contributed to the writing of the manuscript	Designed the study	Conceived and designed the experiments	Methodology	YES
3535694	23336700	ND	PLoS5	Designed the study|Analysed the data|Contributed to the writing of the manuscript	Analysed the data	Analyzed the data	Formal analysis	YES
3535694	23336700	ND	PLoS5	Designed the study|Analysed the data|Contributed to the writing of the manuscript	Contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
3535694	23336700	PM	PLoS5	Designed the study|Analysed the data|Contributed to the writing of the manuscript	Designed the study	Conceived and designed the experiments	Methodology	YES
3535694	23336700	PM	PLoS5	Designed the study|Analysed the data|Contributed to the writing of the manuscript	Analysed the data	Analyzed the data	Formal analysis	YES
3535694	23336700	PM	PLoS5	Designed the study|Analysed the data|Contributed to the writing of the manuscript	Contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
3535694	23336700	SBS	PLoS5	Designed the study|Contributed to the writing of the manuscript	Designed the study	Conceived and designed the experiments	Methodology	YES
3535694	23336700	SBS	PLoS5	Designed the study|Contributed to the writing of the manuscript	Contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
3535694	23336700	SDM	PLoS5	Contributed to the writing of the manuscript	Contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
6410084	30717264	A.C.C.	2	conceived and designed all the experiments	conceived and designed all the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6410084	30717264	B.C.	2	analyzed the data/results	analyzed the data/results	Analyzed the data	Formal analysis	YES
6410084	30717264	L.C.E.	2	carried out all the experiments, analyzed the data/results and wrote the paper	carried out all the experiments, analyzed the data/results and wrote the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6410084	30717264	L.H.	2	carried out the rheological studies	carried out the rheological studies	Performed the experiments	Investigation	YES
6410084	30717264	M.J.R.-L.	2	analyzed histologically the samples of in vivo experiments	analyzed histologically the samples of in vivo experiments	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6410084	30717264	M.S.-A.	2	carried out in vivo experiments and analyzed the data/results	carried out in vivo experiments and analyzed the data/results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5533821	28299518	AC	2	drafted and reviewed sections of the article	drafted and reviewed sections of the article	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5533821	28299518	CB	2	drafted and reviewed sections of the article	drafted and reviewed sections of the article	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5533821	28299518	CK	2	drafted the article|conducted the statistics for the article	drafted the article	Wrote the paper	Writing - Original Draft	YES
5533821	28299518	CK	2	drafted the article|conducted the statistics for the article	conducted the statistics for the article	Analyzed the data	Formal analysis	YES
5533821	28299518	EM	2	drafted and reviewed sections of the article	drafted and reviewed sections of the article	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5533821	28299518	KC	2	drafted and reviewed sections of the article	drafted and reviewed sections of the article	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5533821	28299518	MN	2	conducted the statistics for the article|reviewed findings for accuracy in fieldwork	conducted the statistics for the article	Analyzed the data	Formal analysis	YES
5533821	28299518	MN	2	conducted the statistics for the article|reviewed findings for accuracy in fieldwork	reviewed findings for accuracy in fieldwork	Performed the experiments	Investigation	YES
5533821	28299518	MP	2	drafted the article	drafted the article	Wrote the paper	Writing - Original Draft	YES
5533821	28299518	RK	2	drafted and reviewed sections of the article	drafted and reviewed sections of the article	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5533821	28299518	RL	2	reviewed findings for accuracy in fieldwork	reviewed findings for accuracy in fieldwork	Performed the experiments	Investigation	YES
5533821	28299518	VW	2	drafted and reviewed sections of the article	drafted and reviewed sections of the article	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5533821	28299518	WM	2	drafted and reviewed sections of the article	drafted and reviewed sections of the article	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5442209	28596775	AA	2	contributed to the conception and design of the work|involved in acquisition and analysis of data|were involved in drafting the manuscript	contributed to the conception and design of the work	Conceived and designed the experiments	Conceptualization	YES
5442209	28596775	AA	2	contributed to the conception and design of the work|involved in acquisition and analysis of data|were involved in drafting the manuscript	involved in acquisition and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5442209	28596775	AA	2	contributed to the conception and design of the work|involved in acquisition and analysis of data|were involved in drafting the manuscript	were involved in drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
5442209	28596775	AL	2	contributed to the conception and design of the work|were involved in drafting the manuscript	contributed to the conception and design of the work	Conceived and designed the experiments	Conceptualization	YES
5442209	28596775	AL	2	contributed to the conception and design of the work|were involved in drafting the manuscript	were involved in drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
5442209	28596775	All authors	2	were involved in final approval of version submitted|are accountable for all aspects of the work relating to accuracy and integrity	were involved in final approval of version submitted	-	-	NO
5442209	28596775	All authors	2	were involved in final approval of version submitted|are accountable for all aspects of the work relating to accuracy and integrity	are accountable for all aspects of the work relating to accuracy and integrity	-	-	NO
5442209	28596775	CZ	2	involved in acquisition and analysis of data	involved in acquisition and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5442209	28596775	EO	2	contributed to the conception and design of the work|were involved in drafting the manuscript	contributed to the conception and design of the work	Conceived and designed the experiments	Conceptualization	YES
5442209	28596775	EO	2	contributed to the conception and design of the work|were involved in drafting the manuscript	were involved in drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
5442209	28596775	LG	2	involved in acquisition and analysis of data|were involved in drafting the manuscript	involved in acquisition and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5442209	28596775	LG	2	involved in acquisition and analysis of data|were involved in drafting the manuscript	were involved in drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
5442209	28596775	TH	2	involved in acquisition and analysis of data	involved in acquisition and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5442209	28596775	YJ	2	involved in acquisition and analysis of data|were involved in drafting the manuscript	involved in acquisition and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5442209	28596775	YJ	2	involved in acquisition and analysis of data|were involved in drafting the manuscript	were involved in drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
5442209	28596775	YK	2	involved in acquisition and analysis of data	involved in acquisition and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5442209	28596775	YT	2	involved in acquisition and analysis of data	involved in acquisition and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5013579	27599479	AZ	PLoS52	conceived this study|performed the experiments|analyzed the data|were involved in discussions of the work and manuscript revision	conceived this study	Conceived and designed the experiments	Conceptualization	YES
5013579	27599479	AZ	PLoS52	conceived this study|performed the experiments|analyzed the data|were involved in discussions of the work and manuscript revision	performed the experiments	Performed the experiments	Investigation	YES
5013579	27599479	AZ	PLoS52	conceived this study|performed the experiments|analyzed the data|were involved in discussions of the work and manuscript revision	analyzed the data	Analyzed the data	Formal analysis	YES
5013579	27599479	AZ	PLoS52	conceived this study|performed the experiments|analyzed the data|were involved in discussions of the work and manuscript revision	were involved in discussions of the work and manuscript revision	Wrote the paper	Writing - Review & Editing	YES
5013579	27599479	BD	PLoS52	conceived this study|analyzed the data|were involved in discussions of the work and manuscript revision	conceived this study	Conceived and designed the experiments	Conceptualization	YES
5013579	27599479	BD	PLoS52	conceived this study|analyzed the data|were involved in discussions of the work and manuscript revision	analyzed the data	Analyzed the data	Formal analysis	YES
5013579	27599479	BD	PLoS52	conceived this study|analyzed the data|were involved in discussions of the work and manuscript revision	were involved in discussions of the work and manuscript revision	Wrote the paper	Writing - Review & Editing	YES
5013579	27599479	JW	PLoS52	conceived this study|analyzed the data|were involved in discussions of the work and manuscript revision	conceived this study	Conceived and designed the experiments	Conceptualization	YES
5013579	27599479	JW	PLoS52	conceived this study|analyzed the data|were involved in discussions of the work and manuscript revision	analyzed the data	Analyzed the data	Formal analysis	YES
5013579	27599479	JW	PLoS52	conceived this study|analyzed the data|were involved in discussions of the work and manuscript revision	were involved in discussions of the work and manuscript revision	Wrote the paper	Writing - Review & Editing	YES
5013579	27599479	KF	PLoS52	performed the experiments|were involved in discussions of the work and manuscript revision	performed the experiments	Performed the experiments	Investigation	YES
5013579	27599479	KF	PLoS52	performed the experiments|were involved in discussions of the work and manuscript revision	were involved in discussions of the work and manuscript revision	Wrote the paper	Writing - Review & Editing	YES
5013579	27599479	LG	PLoS52	conceived this study|performed the experiments|analyzed the data|wrote the manuscript	conceived this study	Conceived and designed the experiments	Conceptualization	YES
5013579	27599479	LG	PLoS52	conceived this study|performed the experiments|analyzed the data|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5013579	27599479	LG	PLoS52	conceived this study|performed the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5013579	27599479	LG	PLoS52	conceived this study|performed the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5013579	27599479	WG	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5013579	27599479	WM	PLoS52	were involved in discussions of the work and manuscript revision	were involved in discussions of the work and manuscript revision	Wrote the paper	Writing - Review & Editing	YES
4398454	25874560	FMA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398454	25874560	FMA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398454	25874560	FMA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398454	25874560	FMA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398454	25874560	FMA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398454	25874560	HM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398454	25874560	HM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398454	25874560	HM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398454	25874560	HM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398454	25874560	HM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398454	25874560	MAH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398454	25874560	MAH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398454	25874560	MAH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398454	25874560	MAH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398454	25874560	MAH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398454	25874560	SA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398454	25874560	SA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398454	25874560	SA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398454	25874560	SA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398454	25874560	SA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398454	25874560	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398454	25874560	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398454	25874560	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398454	25874560	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398454	25874560	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4413253	25961030	Tianyu Zhou	2	contribute equally as the co-first authors of the paper	contribute equally as the co-first authors of the paper	-	-	NO
4413253	25961030	Xiping Yan	2	contribute equally as the co-first authors of the paper	contribute equally as the co-first authors of the paper	-	-	NO
6410124	30736367	M.L.-L.	CRediT	Methodology|supervision	Methodology	Performed the experiments	Methodology	YES
6410124	30736367	M.L.-L.	CRediT	Methodology|supervision	supervision	-	Supervision	YES
6410124	30736367	M.L.M.	CRediT	Methodology|supervision|funding acquisition	Methodology	Performed the experiments	Methodology	YES
6410124	30736367	M.L.M.	CRediT	Methodology|supervision|funding acquisition	supervision	-	Supervision	YES
6410124	30736367	M.L.M.	CRediT	Methodology|supervision|funding acquisition	funding acquisition	-	Funding acquisition	YES
6410124	30736367	P.L.-C.	CRediT	Methodology|supervision|funding acquisition	Methodology	Performed the experiments	Methodology	YES
6410124	30736367	P.L.-C.	CRediT	Methodology|supervision|funding acquisition	supervision	-	Supervision	YES
6410124	30736367	P.L.-C.	CRediT	Methodology|supervision|funding acquisition	funding acquisition	-	Funding acquisition	YES
5442247	28596782	GN	2	contributed equally writing the review	contributed equally writing the review	Wrote the paper	Writing - Review & Editing	YES
5442247	28596782	HK	2	contributed equally writing the review	contributed equally writing the review	Wrote the paper	Writing - Review & Editing	YES
3536941	23336727	AG	2	contributed to conceptualization of the study, interpretation of the day, critical revision of the manuscript and final approval of the manuscript	contributed to conceptualization of the study, interpretation of the day, critical revision of the manuscript and final approval of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Review & Editing	YES
3536941	23336727	All authors	2	have read and approved the final version	have read and approved the final version	-	-	NO
3536941	23336727	BM	2	contributed to analysis and interpretation of the data, critical revision of the manuscript and final approval of the manuscript	contributed to analysis and interpretation of the data, critical revision of the manuscript and final approval of the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
3536941	23336727	BON	2	contributed to conceptualization of the study, interpretation of the day, critical revision of the manuscript and final approval of the manuscript	contributed to conceptualization of the study, interpretation of the day, critical revision of the manuscript and final approval of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Review & Editing	YES
3536941	23336727	HL	2	contributed to analysis and interpretation of the data, critical revision of the manuscript and final approval of the manuscript	contributed to analysis and interpretation of the data, critical revision of the manuscript and final approval of the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
3536941	23336727	KWK	2	contributed to conceptualization of the study, acquisition of data, analysis and interpretation of the data, drafting of the manuscript and final approval of the manuscript	contributed to conceptualization of the study, acquisition of data, analysis and interpretation of the data, drafting of the manuscript and final approval of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Resources|Writing - Original Draft	YES
3536941	23336727	PA	2	contributed to conceptualization of the study, acquisition of data, interpretation of the data, critical revision of the manuscript and final approval of the manuscript	contributed to conceptualization of the study, acquisition of data, interpretation of the data, critical revision of the manuscript and final approval of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Resources|Writing - Review & Editing	YES
3536941	23336727	PB	2	contributed to conceptualization of the study, critical revision of the manuscript and final approval of the manuscript	contributed to conceptualization of the study, critical revision of the manuscript and final approval of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
3536941	23336727	WN	2	contributed to conceptualization of the study, acquisition of data, interpretation of the data, critical revision of the manuscript and final approval of the manuscript	contributed to conceptualization of the study, acquisition of data, interpretation of the data, critical revision of the manuscript and final approval of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Resources|Writing - Review & Editing	YES
5964546	20836797	D Division	2	of pediatric infectious diseases dr	of pediatric infectious diseases dr	-	-	NO
5443144	28596781	JL	PLoS52	designed the experiments|carried out the experiments|analyzed the data|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5443144	28596781	JL	PLoS52	designed the experiments|carried out the experiments|analyzed the data|wrote the manuscript	carried out the experiments	Performed the experiments	Investigation	YES
5443144	28596781	JL	PLoS52	designed the experiments|carried out the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5443144	28596781	JL	PLoS52	designed the experiments|carried out the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5443144	28596781	LM	PLoS52	designed the experiments|wrote the manuscript|supervised the project	designed the experiments	Conceived and designed the experiments	Methodology	YES
5443144	28596781	LM	PLoS52	designed the experiments|wrote the manuscript|supervised the project	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5443144	28596781	LM	PLoS52	designed the experiments|wrote the manuscript|supervised the project	supervised the project	-	Supervision	YES
5443144	28596781	YC	PLoS52	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5443144	28596781	YH	PLoS52	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5443144	28596781	ZW	PLoS52	designed the experiments|carried out the experiments|analyzed the data|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5443144	28596781	ZW	PLoS52	designed the experiments|carried out the experiments|analyzed the data|wrote the manuscript	carried out the experiments	Performed the experiments	Investigation	YES
5443144	28596781	ZW	PLoS52	designed the experiments|carried out the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5443144	28596781	ZW	PLoS52	designed the experiments|carried out the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5015234	27604219	AP	2	analyzed the data under the	analyzed the data under the	Analyzed the data	Formal analysis	YES
5015234	27604219	SB	2	supervised ap analyzed the data under the	supervised ap analyzed the data under the	Analyzed the data	Formal analysis|Supervision	YES
3905933	24489435	All authors	2	have given approval to the final version of the manuscript	have given approval to the final version of the manuscript	-	-	NO
3905933	24489435	J.S.	2	also carried out the experiments and analyzed the data	also carried out the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3905933	24489435	all authors	2	also carried out the experiments and analyzed the data	also carried out the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3354680	22629151	All the authors	2	contributed in all aspects of the study ranging from the design of the study, experimental procedures, to writing of manuscript	contributed in all aspects of the study ranging from the design of the study, experimental procedures, to writing of manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
4398455	25875839	AB	PLoS5	Conceived and designed the experiments|Provided input in the final revision of the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398455	25875839	AB	PLoS5	Conceived and designed the experiments|Provided input in the final revision of the manuscript	Provided input in the final revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4398455	25875839	FN	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398455	25875839	FN	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398455	25875839	FN	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398455	25875839	GMT	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398455	25875839	GMT	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398455	25875839	JAE	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398455	25875839	KH	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4398455	25875839	KH	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398455	25875839	VS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4398455	25875839	VS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398455	25875839	YS	PLoS5	Conceived and designed the experiments|Provided input in the final revision of the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398455	25875839	YS	PLoS5	Conceived and designed the experiments|Provided input in the final revision of the manuscript	Provided input in the final revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
6410172	30781867	All authors	2	contributed conceptually, to drafting, to figure and table designs, and to the final editing	contributed conceptually, to drafting, to figure and table designs, and to the final editing	Conceived and designed the experiments|Wrote the paper	Conceptualization|Visualization|Writing - Original Draft|Writing - Review & Editing	YES
4413255	25961014	All authors	2	conceptualised and wrote the paper together	conceptualised and wrote the paper together	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4413255	25961014	Menghan Liu	2	contributed equally to this work	contributed equally to this work	-	-	NO
4413255	25961014	Sanket Joshi	2	contributed equally to this work	contributed equally to this work	-	-	NO
3545202	23336726	AW	2	provided technical and intellectual input into the study design, data collection tools, fieldwork, and data analysis, and reviewed multiple drafts of the manuscript	provided technical and intellectual input into the study design, data collection tools, fieldwork, and data analysis, and reviewed multiple drafts of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
3545202	23336726	DS	2	contributed to the study design and reviewed drafts of the manuscript	contributed to the study design and reviewed drafts of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft|Writing - Review & Editing	YES
3545202	23336726	JK	2	contributed to the design of the survey instrument, coordinated the client survey and reviewed drafts of the manuscript	contributed to the design of the survey instrument, coordinated the client survey and reviewed drafts of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Project administration|Writing - Original Draft|Writing - Review & Editing	YES
3545202	23336726	KC	2	led the study design, development of data collection tools, data collection and analysis, and drafted and finalized the manuscript	led the study design, development of data collection tools, data collection and analysis, and drafted and finalized the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
3545202	23336726	PF	2	contributed to the design of data collection tools, conducted interviews with clients at the clinics, contributed to data analysis and reviewed the manuscript	contributed to the design of data collection tools, conducted interviews with clients at the clinics, contributed to data analysis and reviewed the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Review & Editing	YES
3545202	23336726	RN	2	contributed to the study design and reviewed drafts of the manuscript	contributed to the study design and reviewed drafts of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft|Writing - Review & Editing	YES
3545202	23336726	SM	2	provided technical and intellectual input into the study design, data collection tools, fieldwork, and data analysis, and reviewed multiple drafts of the manuscript	provided technical and intellectual input into the study design, data collection tools, fieldwork, and data analysis, and reviewed multiple drafts of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5443146	28596773	JT	2	revised and finalized the paper	revised and finalized the paper	Wrote the paper	Writing - Review & Editing	YES
5443146	28596773	KS	2	did the data analyses	did the data analyses	Analyzed the data	Formal analysis	YES
5443146	28596773	LS	2	designed the experiment	designed the experiment	Conceived and designed the experiments	Methodology	YES
5443146	28596773	NK	2	revised and finalized the paper	revised and finalized the paper	Wrote the paper	Writing - Review & Editing	YES
5443146	28596773	QM	2	carried out most of the experiments and drafted manuscript	carried out most of the experiments and drafted manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5443146	28596773	XL	2	designed the experiment	designed the experiment	Conceived and designed the experiments	Methodology	YES
5443146	28596773	YY	2	did the data analyses	did the data analyses	Analyzed the data	Formal analysis	YES
5443146	28596773	ZZ	2	did the data analyses	did the data analyses	Analyzed the data	Formal analysis	YES
5964547	20629773	A Dixon	2	managed the data collection	managed the data collection	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5964547	20629773	All authors	2	contributed to developing waive study protocol|revised the manuscript critically and approved the final version for submission	contributed to developing waive study protocol	Conceived and designed the experiments	Methodology	YES
5964547	20629773	All authors	2	contributed to developing waive study protocol|revised the manuscript critically and approved the final version for submission	revised the manuscript critically and approved the final version for submission	Wrote the paper	Writing - Review & Editing	YES
5964547	20629773	C Moore	2	led the writing of the manuscript	led the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5964547	20629773	D Carcione	2	managed the data collection|were involved in data analysis	managed the data collection	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5964547	20629773	D Carcione	2	managed the data collection|were involved in data analysis	were involved in data analysis	Analyzed the data	Formal analysis	YES
5964547	20629773	D Keil	2	were involved in the laboratory testing of samples and interpretation of results	were involved in the laboratory testing of samples and interpretation of results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5964547	20629773	P Jacoby	2	were involved in data analysis	were involved in data analysis	Analyzed the data	Formal analysis	YES
5964547	20629773	P Richmond	2	managed the data collection	managed the data collection	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5964547	20629773	S Williams	2	managed the data collection|were involved in the laboratory testing of samples and interpretation of results	managed the data collection	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5964547	20629773	S Williams	2	managed the data collection|were involved in the laboratory testing of samples and interpretation of results	were involved in the laboratory testing of samples and interpretation of results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3914394	24511184	All authors	2	contributed equally	contributed equally	-	-	NO
5015259	27604148	KM	2	contributed to the development of the project and edited the manuscript	contributed to the development of the project and edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5015259	27604148	MM	2	conceived and designed the study|contributed to the development of the project and edited the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5015259	27604148	MM	2	conceived and designed the study|contributed to the development of the project and edited the manuscript	contributed to the development of the project and edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5015259	27604148	MN	2	conceived and designed the study|coordinated the study and helped to draft the manuscript|contributed to the development of the project and edited the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5015259	27604148	MN	2	conceived and designed the study|coordinated the study and helped to draft the manuscript|contributed to the development of the project and edited the manuscript	coordinated the study and helped to draft the manuscript	Wrote the paper	Project administration|Writing - Original Draft	YES
5015259	27604148	MN	2	conceived and designed the study|coordinated the study and helped to draft the manuscript|contributed to the development of the project and edited the manuscript	contributed to the development of the project and edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5015259	27604148	TPS	2	conceived and designed the study|conducted the molecular work and data analysis and drafted the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5015259	27604148	TPS	2	conceived and designed the study|conducted the molecular work and data analysis and drafted the manuscript	conducted the molecular work and data analysis and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6410174	30795556	E.A.	5	prepared section 1	prepared section 1	-	-	NO
6410174	30795556	E.P.	5	prepared section 2	prepared section 2	-	-	NO
6410174	30795556	N.K.	5	prepared section 3	prepared section 3	-	-	NO
4398456	25875357	CT	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398456	25875357	HN	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398456	25875357	KS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398456	25875357	KS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398456	25875357	KS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398456	25875357	KS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398456	25875357	MD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398456	25875357	MD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398456	25875357	MD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398456	25875357	OK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398456	25875357	OK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398456	25875357	OK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398456	25875357	OK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6410185	30691114	A.C.	CRediT	Conceptualization|writing--review and editing|supervision	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6410185	30691114	A.C.	CRediT	Conceptualization|writing--review and editing|supervision	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6410185	30691114	A.C.	CRediT	Conceptualization|writing--review and editing|supervision	supervision	-	Supervision	YES
6410185	30691114	C.A.-L.	CRediT	Conceptualization|methodology|resources|writing--review and editing|supervision	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6410185	30691114	C.A.-L.	CRediT	Conceptualization|methodology|resources|writing--review and editing|supervision	methodology	Performed the experiments	Methodology	YES
6410185	30691114	C.A.-L.	CRediT	Conceptualization|methodology|resources|writing--review and editing|supervision	resources	Contributed reagents/materials/analysis tools	Resources	YES
6410185	30691114	C.A.-L.	CRediT	Conceptualization|methodology|resources|writing--review and editing|supervision	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6410185	30691114	C.A.-L.	CRediT	Conceptualization|methodology|resources|writing--review and editing|supervision	supervision	-	Supervision	YES
6410185	30691114	P.T.	CRediT	Conceptualization|validation|resources|writing--review and editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6410185	30691114	P.T.	CRediT	Conceptualization|validation|resources|writing--review and editing	validation	Performed the experiments	Validation	YES
6410185	30691114	P.T.	CRediT	Conceptualization|validation|resources|writing--review and editing	resources	Contributed reagents/materials/analysis tools	Resources	YES
6410185	30691114	P.T.	CRediT	Conceptualization|validation|resources|writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6410185	30691114	S.B.	CRediT	Conceptualization|validation|writing--review and editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6410185	30691114	S.B.	CRediT	Conceptualization|validation|writing--review and editing	validation	Performed the experiments	Validation	YES
6410185	30691114	S.B.	CRediT	Conceptualization|validation|writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6410185	30691114	S.C.-M.	CRediT	methodology|validation|writing--original draft preparation	methodology	Performed the experiments	Methodology	YES
6410185	30691114	S.C.-M.	CRediT	methodology|validation|writing--original draft preparation	validation	Performed the experiments	Validation	YES
6410185	30691114	S.C.-M.	CRediT	methodology|validation|writing--original draft preparation	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
3545274	23336725	AC	2	critically reviewed and revised the manuscript for intellectual content	critically reviewed and revised the manuscript for intellectual content	Wrote the paper	Writing - Review & Editing	YES
3545274	23336725	AD	2	critically reviewed and revised the manuscript for intellectual content	critically reviewed and revised the manuscript for intellectual content	Wrote the paper	Writing - Review & Editing	YES
3545274	23336725	AJC	2	conducted the augmented search for literature in the reference lists of eligible articles and the grey literature|analyzed the data, interpreted the results and wrote the first draft of the article	conducted the augmented search for literature in the reference lists of eligible articles and the grey literature	Performed the experiments	Formal analysis|Investigation	YES
3545274	23336725	AJC	2	conducted the augmented search for literature in the reference lists of eligible articles and the grey literature|analyzed the data, interpreted the results and wrote the first draft of the article	analyzed the data, interpreted the results and wrote the first draft of the article	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3545274	23336725	AK	2	critically reviewed and revised the manuscript for intellectual content	critically reviewed and revised the manuscript for intellectual content	Wrote the paper	Writing - Review & Editing	YES
3545274	23336725	AP	2	critically reviewed and revised the manuscript for intellectual content	critically reviewed and revised the manuscript for intellectual content	Wrote the paper	Writing - Review & Editing	YES
3545274	23336725	All authors	2	contributed to the conceptualization and design of the review	contributed to the conceptualization and design of the review	Conceived and designed the experiments	Conceptualization	YES
3545274	23336725	CHIWOS	2	reviewed, edited and approved the final draft	reviewed, edited and approved the final draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3545274	23336725	KA	2	critically reviewed and revised the manuscript for intellectual content	critically reviewed and revised the manuscript for intellectual content	Wrote the paper	Writing - Review & Editing	YES
3545274	23336725	ML	2	critically reviewed and revised the manuscript for intellectual content	critically reviewed and revised the manuscript for intellectual content	Wrote the paper	Writing - Review & Editing	YES
3545274	23336725	MS	2	critically reviewed and revised the manuscript for intellectual content	critically reviewed and revised the manuscript for intellectual content	Wrote the paper	Writing - Review & Editing	YES
3545274	23336725	NO	2	critically reviewed and revised the manuscript for intellectual content	critically reviewed and revised the manuscript for intellectual content	Wrote the paper	Writing - Review & Editing	YES
3545274	23336725	Research Team	2	reviewed, edited and approved the final draft	reviewed, edited and approved the final draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3545274	23336725	SB	2	carried out the initial literature search in online databases	carried out the initial literature search in online databases	Performed the experiments|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Software	YES
3545274	23336725	SG	2	critically reviewed and revised the manuscript for intellectual content	critically reviewed and revised the manuscript for intellectual content	Wrote the paper	Writing - Review & Editing	YES
3545274	23336725	SM	2	critically reviewed and revised the manuscript for intellectual content	critically reviewed and revised the manuscript for intellectual content	Wrote the paper	Writing - Review & Editing	YES
3545274	23336725	WT	2	critically reviewed and revised the manuscript for intellectual content	critically reviewed and revised the manuscript for intellectual content	Wrote the paper	Writing - Review & Editing	YES
5015328	27605362	AS	2	conceived and designed the rna seq screen|performed the bioinformatics analyses|analyzed the results|wrote the manuscript and all authors read and approved the contents	conceived and designed the rna seq screen	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5015328	27605362	AS	2	conceived and designed the rna seq screen|performed the bioinformatics analyses|analyzed the results|wrote the manuscript and all authors read and approved the contents	performed the bioinformatics analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5015328	27605362	AS	2	conceived and designed the rna seq screen|performed the bioinformatics analyses|analyzed the results|wrote the manuscript and all authors read and approved the contents	analyzed the results	Analyzed the data	Formal analysis	YES
5015328	27605362	AS	2	conceived and designed the rna seq screen|performed the bioinformatics analyses|analyzed the results|wrote the manuscript and all authors read and approved the contents	wrote the manuscript and all authors read and approved the contents	Wrote the paper	Writing - Original Draft	YES
5015328	27605362	KL	2	performed some of the qpcr studies	performed some of the qpcr studies	Performed the experiments	Investigation	YES
5015328	27605362	MB	2	analyzed the results	analyzed the results	Analyzed the data	Formal analysis	YES
5015328	27605362	UG	2	conceived and designed the rna seq screen|analyzed the results|wrote the manuscript and all authors read and approved the contents	conceived and designed the rna seq screen	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5015328	27605362	UG	2	conceived and designed the rna seq screen|analyzed the results|wrote the manuscript and all authors read and approved the contents	analyzed the results	Analyzed the data	Formal analysis	YES
5015328	27605362	UG	2	conceived and designed the rna seq screen|analyzed the results|wrote the manuscript and all authors read and approved the contents	wrote the manuscript and all authors read and approved the contents	Wrote the paper	Writing - Original Draft	YES
5015328	27605362	VC	2	performed the bioinformatics analyses	performed the bioinformatics analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5443152	28596779	AB	2	designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
5443152	28596779	AG	2	designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
5443152	28596779	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5443152	28596779	IM	2	performed the research	performed the research	Performed the experiments	Investigation	YES
5443152	28596779	ML	2	performed the research	performed the research	Performed the experiments	Investigation	YES
5443152	28596779	PC	2	designed the research|wrote the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
5443152	28596779	PC	2	designed the research|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5443152	28596779	RS	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4398458	25875098	DEB	PLoS5	Platform development work	Platform development work	-	-	NO
4398458	25875098	DR	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4398458	25875098	DR	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4398458	25875098	DSW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398458	25875098	DSW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4398458	25875098	DSW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4398458	25875098	EWM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398458	25875098	EWM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398458	25875098	EWM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398458	25875098	FB	PLoS5	Platform development work	Platform development work	-	-	NO
4398458	25875098	JW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398458	25875098	JW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398458	25875098	JW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398458	25875098	KWF	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398458	25875098	KWF	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398458	25875098	LDA	PLoS5	Conceived and designed the experiments|Platform development work	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398458	25875098	LDA	PLoS5	Conceived and designed the experiments|Platform development work	Platform development work	-	-	NO
4398458	25875098	MP	PLoS5	Conceived and designed the experiments|Wrote the paper|Platform development work	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398458	25875098	MP	PLoS5	Conceived and designed the experiments|Wrote the paper|Platform development work	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398458	25875098	MP	PLoS5	Conceived and designed the experiments|Wrote the paper|Platform development work	Platform development work	-	-	NO
4398458	25875098	RS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4398458	25875098	RS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4398458	25875098	SR	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4398458	25875098	SR	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4398458	25875098	ST	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398458	25875098	ST	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398458	25875098	ST	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398458	25875098	YP	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4398458	25875098	YP	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4166460	25065293	All authors	2	contributed to manuscript review	contributed to manuscript review	Wrote the paper	Writing - Review & Editing	YES
4166460	25065293	D Cameron	2	was responsible for the design of the ql sub-study and manuscript writing and contributed to data interpretation	was responsible for the design of the ql sub-study and manuscript writing and contributed to data interpretation	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4166460	25065293	E Hall	2	was responsible for study design, trial management, statistical data interpretation, manuscript writing and oversaw all statistical analyses	was responsible for study design, trial management, statistical data interpretation, manuscript writing and oversaw all statistical analyses	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Data curation|Formal analysis|Methodology|Project administration|Supervision|Writing - Original Draft	YES
4166460	25065293	J M Bliss	2	was responsible for study design, trial management, data interpretation, contributed to manuscript writing and oversaw all statistical analyses	was responsible for study design, trial management, data interpretation, contributed to manuscript writing and oversaw all statistical analyses	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Data curation|Formal analysis|Methodology|Project administration|Supervision|Writing - Original Draft	YES
4166460	25065293	P Hopwood	2	was responsible for the design and management of the ql sub-study, clinical data interpretation and manuscript writing	was responsible for the design and management of the ql sub-study, clinical data interpretation and manuscript writing	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Data curation|Formal analysis|Methodology|Project administration|Writing - Original Draft	YES
4166460	25065293	R Waters	2	conducted the statistical analyses	conducted the statistical analyses	Analyzed the data	Formal analysis	YES
4166460	25065293	S Crawford	2	was responsible for trial management and data collection	was responsible for trial management and data collection	Performed the experiments|Analyzed the data	Data curation|Investigation|Project administration	YES
4166460	25065293	TACT	2	trial and contributed to study design, data interpretation and manuscript writing	trial and contributed to study design, data interpretation and manuscript writing	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Original Draft	YES
6410192	30823545	A.A.K.	CRediT	Conceptualization|methodology|software|validation|formal analysis|investigation|resources|writing--original draft preparation|writing--review and editing|supervision	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6410192	30823545	A.A.K.	CRediT	Conceptualization|methodology|software|validation|formal analysis|investigation|resources|writing--original draft preparation|writing--review and editing|supervision	methodology	Performed the experiments	Methodology	YES
6410192	30823545	A.A.K.	CRediT	Conceptualization|methodology|software|validation|formal analysis|investigation|resources|writing--original draft preparation|writing--review and editing|supervision	software	Contributed reagents/materials/analysis tools	Software	YES
6410192	30823545	A.A.K.	CRediT	Conceptualization|methodology|software|validation|formal analysis|investigation|resources|writing--original draft preparation|writing--review and editing|supervision	validation	Performed the experiments	Validation	YES
6410192	30823545	A.A.K.	CRediT	Conceptualization|methodology|software|validation|formal analysis|investigation|resources|writing--original draft preparation|writing--review and editing|supervision	formal analysis	Analyzed the data	Formal analysis	YES
6410192	30823545	A.A.K.	CRediT	Conceptualization|methodology|software|validation|formal analysis|investigation|resources|writing--original draft preparation|writing--review and editing|supervision	investigation	Performed the experiments	Investigation	YES
6410192	30823545	A.A.K.	CRediT	Conceptualization|methodology|software|validation|formal analysis|investigation|resources|writing--original draft preparation|writing--review and editing|supervision	resources	Contributed reagents/materials/analysis tools	Resources	YES
6410192	30823545	A.A.K.	CRediT	Conceptualization|methodology|software|validation|formal analysis|investigation|resources|writing--original draft preparation|writing--review and editing|supervision	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6410192	30823545	A.A.K.	CRediT	Conceptualization|methodology|software|validation|formal analysis|investigation|resources|writing--original draft preparation|writing--review and editing|supervision	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6410192	30823545	A.A.K.	CRediT	Conceptualization|methodology|software|validation|formal analysis|investigation|resources|writing--original draft preparation|writing--review and editing|supervision	supervision	-	Supervision	YES
6410192	30823545	J.M.	CRediT	software|investigation|writing--original draft preparation|writing--review and editing	software	Contributed reagents/materials/analysis tools	Software	YES
6410192	30823545	J.M.	CRediT	software|investigation|writing--original draft preparation|writing--review and editing	investigation	Performed the experiments	Investigation	YES
6410192	30823545	J.M.	CRediT	software|investigation|writing--original draft preparation|writing--review and editing	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6410192	30823545	J.M.	CRediT	software|investigation|writing--original draft preparation|writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6410192	30823545	S.A.	CRediT	software|investigation|writing--original draft preparation|writing--review and editing	software	Contributed reagents/materials/analysis tools	Software	YES
6410192	30823545	S.A.	CRediT	software|investigation|writing--original draft preparation|writing--review and editing	investigation	Performed the experiments	Investigation	YES
6410192	30823545	S.A.	CRediT	software|investigation|writing--original draft preparation|writing--review and editing	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6410192	30823545	S.A.	CRediT	software|investigation|writing--original draft preparation|writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6410192	30823545	V.M.	CRediT	software|investigation|writing--original draft preparation|writing--review and editing	software	Contributed reagents/materials/analysis tools	Software	YES
6410192	30823545	V.M.	CRediT	software|investigation|writing--original draft preparation|writing--review and editing	investigation	Performed the experiments	Investigation	YES
6410192	30823545	V.M.	CRediT	software|investigation|writing--original draft preparation|writing--review and editing	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6410192	30823545	V.M.	CRediT	software|investigation|writing--original draft preparation|writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6410192	30823545	Y.D.	CRediT	Conceptualization|methodology|validation|formal analysis|investigation|resources|writing--original draft preparation|writing--review and editing|project administration	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6410192	30823545	Y.D.	CRediT	Conceptualization|methodology|validation|formal analysis|investigation|resources|writing--original draft preparation|writing--review and editing|project administration	methodology	Performed the experiments	Methodology	YES
6410192	30823545	Y.D.	CRediT	Conceptualization|methodology|validation|formal analysis|investigation|resources|writing--original draft preparation|writing--review and editing|project administration	validation	Performed the experiments	Validation	YES
6410192	30823545	Y.D.	CRediT	Conceptualization|methodology|validation|formal analysis|investigation|resources|writing--original draft preparation|writing--review and editing|project administration	formal analysis	Analyzed the data	Formal analysis	YES
6410192	30823545	Y.D.	CRediT	Conceptualization|methodology|validation|formal analysis|investigation|resources|writing--original draft preparation|writing--review and editing|project administration	investigation	Performed the experiments	Investigation	YES
6410192	30823545	Y.D.	CRediT	Conceptualization|methodology|validation|formal analysis|investigation|resources|writing--original draft preparation|writing--review and editing|project administration	resources	Contributed reagents/materials/analysis tools	Resources	YES
6410192	30823545	Y.D.	CRediT	Conceptualization|methodology|validation|formal analysis|investigation|resources|writing--original draft preparation|writing--review and editing|project administration	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6410192	30823545	Y.D.	CRediT	Conceptualization|methodology|validation|formal analysis|investigation|resources|writing--original draft preparation|writing--review and editing|project administration	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6410192	30823545	Y.D.	CRediT	Conceptualization|methodology|validation|formal analysis|investigation|resources|writing--original draft preparation|writing--review and editing|project administration	project administration	-	Project administration	YES
3547123	23336728	All	2	writing committee members have read and approved the final manuscript|regional cohorts have received and approved the final manuscript	writing committee members have read and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3547123	23336728	All	2	writing committee members have read and approved the final manuscript|regional cohorts have received and approved the final manuscript	regional cohorts have received and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5016863	27608714	DL	2	carried out rna extraction, globin depletion, and qpcr analyses and participated in cosinor analyses	carried out rna extraction, globin depletion, and qpcr analyses and participated in cosinor analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5016863	27608714	FVD	2	conceived of the study, participated in the design of the study, carried out wgcna analyses and participated in writing the manuscript	conceived of the study, participated in the design of the study, carried out wgcna analyses and participated in writing the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5016863	27608714	JSM	2	participated in rna extraction and globin depletion, carried out rna seq data analysis, de novo transcriptome assembly, differential expression, enrichment, and cosinor analyses and drafted the manuscript	participated in rna extraction and globin depletion, carried out rna seq data analysis, de novo transcriptome assembly, differential expression, enrichment, and cosinor analyses and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5016863	27608714	LHS	2	participated in the design of the study	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
5016863	27608714	MC	2	participated in the design of the study and provided samples and corresponding hematological and environmental data	participated in the design of the study and provided samples and corresponding hematological and environmental data	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Methodology|Resources	YES
5016863	27608714	MGN	2	carried out pca analyses	carried out pca analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5016863	27608714	PEA	2	provided computational support and assisted in data analysis	provided computational support and assisted in data analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5683943	28501964	All co-authors	2	gave feedback on the draft statement and participated in refining the document	gave feedback on the draft statement and participated in refining the document	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5683943	28501964	LTM	2	drafted the statement|incorporated their feedback to develop a penultimate draft of the manuscript	drafted the statement	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5683943	28501964	LTM	2	drafted the statement|incorporated their feedback to develop a penultimate draft of the manuscript	incorporated their feedback to develop a penultimate draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
6410193	30781442	A.K.	7	contributed to the initial planning and experimental design	contributed to the initial planning and experimental design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6410193	30781442	A.R.	7	Led, interpret and revised SDS-PAGE work	Led, interpret and revised SDS-PAGE work	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
6410193	30781442	H.K.G.S.	7	experimental work	experimental work	Performed the experiments	Investigation	YES
6410193	30781442	M.K.	7	initial planning, experimental design, data analysis, supervision and wrote the first draft and led the submission	initial planning, experimental design, data analysis, supervision and wrote the first draft and led the submission	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Supervision|Writing - Original Draft	YES
6410193	30781442	R.G.A.	7	supervision, contributed to the data interpretation and edited the drafts	supervision, contributed to the data interpretation and edited the drafts	Analyzed the data|Wrote the paper	Formal analysis|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
4398459	25874630	BJS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398459	25874630	BJS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398459	25874630	BJS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398459	25874630	BJS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398459	25874630	CTH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398459	25874630	CTH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398459	25874630	CTH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398459	25874630	CTH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398459	25874630	CTH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398459	25874630	JAF	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398459	25874630	JAF	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398459	25874630	JAF	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398459	25874630	KMH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398459	25874630	KMH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398459	25874630	KMH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398459	25874630	MEH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398459	25874630	MEH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398459	25874630	MEH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398459	25874630	MEH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398459	25874630	MEH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398459	25874630	RMD	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398459	25874630	RMD	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398459	25874630	RMD	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398459	25874630	RNR	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398459	25874630	RNR	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398459	25874630	SJO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398459	25874630	SJO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398459	25874630	SJO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398459	25874630	SJO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398459	25874630	SJO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5443154	28596783	EP	2	participated in the data analysis	participated in the data analysis	Analyzed the data	Formal analysis	YES
5443154	28596783	HZ	2	conceived and designed the study, and wrote the manuscript|performed the bioinformatic analysis and the experiments	conceived and designed the study, and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
5443154	28596783	HZ	2	conceived and designed the study, and wrote the manuscript|performed the bioinformatic analysis and the experiments	performed the bioinformatic analysis and the experiments	Performed the experiments	Formal analysis|Investigation	YES
5443154	28596783	XZ	2	performed the bioinformatic analysis and the experiments	performed the bioinformatic analysis and the experiments	Performed the experiments	Formal analysis|Investigation	YES
5443154	28596783	YxZ	2	performed the bioinformatic analysis and the experiments	performed the bioinformatic analysis and the experiments	Performed the experiments	Formal analysis|Investigation	YES
5443154	28596783	YyZ	2	participated in the data analysis	participated in the data analysis	Analyzed the data	Formal analysis	YES
3551982	23336724	AK	PLoS5	Conceptualized and designed the study|Analyzed the data	Conceptualized and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3551982	23336724	AK	PLoS5	Conceptualized and designed the study|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
3551982	23336724	BM	PLoS5	Conceptualized and designed the study|Collected existing data records|Analyzed the data	Conceptualized and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3551982	23336724	BM	PLoS5	Conceptualized and designed the study|Collected existing data records|Analyzed the data	Collected existing data records	Performed the experiments	Investigation	YES
3551982	23336724	BM	PLoS5	Conceptualized and designed the study|Collected existing data records|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
3551982	23336724	JG	PLoS5	Conceptualized and designed the study	Conceptualized and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4413514	25960998	Gang Wang	2	contributed equally to the work	contributed equally to the work	-	-	NO
4413514	25960998	Yue Huang	2	contributed equally to the work	contributed equally to the work	-	-	NO
5016927	27612452	AB	2	designed the web server|implemented the web server	designed the web server	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
5016927	27612452	AB	2	designed the web server|implemented the web server	implemented the web server	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5016927	27612452	DA	2	designed the web server|implemented the web server	designed the web server	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
5016927	27612452	DA	2	designed the web server|implemented the web server	implemented the web server	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5016927	27612452	XY	2	designed the web server	designed the web server	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
3982936	24741204	All authors	2	were involved in the discussions and commented on and revised successive drafts of the manuscript	were involved in the discussions and commented on and revised successive drafts of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3982936	24741204	C.R.S.	2	performed and analyzed the temperature dependent resistivity and mr measurements	performed and analyzed the temperature dependent resistivity and mr measurements	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3982936	24741204	J.H.	2	planned and performed the thin film depositions|were involved in the discussions and commented on and revised successive drafts of the manuscript	planned and performed the thin film depositions	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
3982936	24741204	J.H.	2	planned and performed the thin film depositions|were involved in the discussions and commented on and revised successive drafts of the manuscript	were involved in the discussions and commented on and revised successive drafts of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3982936	24741204	K.M.C.	2	measured and analyzed the optical transmittance properties	measured and analyzed the optical transmittance properties	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3982936	24741204	L.H.	2	conceived and initiated the research|supervised the work	conceived and initiated the research	Conceived and designed the experiments	Conceptualization	YES
3982936	24741204	L.H.	2	conceived and initiated the research|supervised the work	supervised the work	-	Supervision	YES
3982936	24741204	M.R.L.	2	performed the intercalation and deintercalation experiments	performed the intercalation and deintercalation experiments	Performed the experiments	Investigation	YES
3982936	24741204	M.W.B.	2	conceived and initiated the research|supervised the work	conceived and initiated the research	Conceived and designed the experiments	Conceptualization	YES
3982936	24741204	M.W.B.	2	conceived and initiated the research|supervised the work	supervised the work	-	Supervision	YES
3982936	24741204	P.E.	2	were involved in the discussions and commented on and revised successive drafts of the manuscript|supervised the work	were involved in the discussions and commented on and revised successive drafts of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3982936	24741204	P.E.	2	were involved in the discussions and commented on and revised successive drafts of the manuscript|supervised the work	supervised the work	-	Supervision	YES
3982936	24741204	S.J.M.	2	performed and analyzed the temperature dependent resistivity and mr measurements	performed and analyzed the temperature dependent resistivity and mr measurements	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3982936	24741204	Y.G.	2	conceived and initiated the research|supervised the work	conceived and initiated the research	Conceived and designed the experiments	Conceptualization	YES
3982936	24741204	Y.G.	2	conceived and initiated the research|supervised the work	supervised the work	-	Supervision	YES
6410202	30744154	A.B.	CRediT	Conceptualization|methodology|formal analysis|investigation|data curation|writing--original draft preparation|writing--review and editing|visualization	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6410202	30744154	A.B.	CRediT	Conceptualization|methodology|formal analysis|investigation|data curation|writing--original draft preparation|writing--review and editing|visualization	methodology	Performed the experiments	Methodology	YES
6410202	30744154	A.B.	CRediT	Conceptualization|methodology|formal analysis|investigation|data curation|writing--original draft preparation|writing--review and editing|visualization	formal analysis	Analyzed the data	Formal analysis	YES
6410202	30744154	A.B.	CRediT	Conceptualization|methodology|formal analysis|investigation|data curation|writing--original draft preparation|writing--review and editing|visualization	investigation	Performed the experiments	Investigation	YES
6410202	30744154	A.B.	CRediT	Conceptualization|methodology|formal analysis|investigation|data curation|writing--original draft preparation|writing--review and editing|visualization	data curation	Analyzed the data	Data curation	YES
6410202	30744154	A.B.	CRediT	Conceptualization|methodology|formal analysis|investigation|data curation|writing--original draft preparation|writing--review and editing|visualization	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6410202	30744154	A.B.	CRediT	Conceptualization|methodology|formal analysis|investigation|data curation|writing--original draft preparation|writing--review and editing|visualization	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6410202	30744154	A.B.	CRediT	Conceptualization|methodology|formal analysis|investigation|data curation|writing--original draft preparation|writing--review and editing|visualization	visualization	Analyzed the data	Visualization	YES
6410202	30744154	A.K.	CRediT	investigation|writing--review and editing|visualization	investigation	Performed the experiments	Investigation	YES
6410202	30744154	A.K.	CRediT	investigation|writing--review and editing|visualization	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6410202	30744154	A.K.	CRediT	investigation|writing--review and editing|visualization	visualization	Analyzed the data	Visualization	YES
6410202	30744154	C.P.	CRediT	resources|writing--review and editing|supervision|funding acquisition	resources	Contributed reagents/materials/analysis tools	Resources	YES
6410202	30744154	C.P.	CRediT	resources|writing--review and editing|supervision|funding acquisition	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6410202	30744154	C.P.	CRediT	resources|writing--review and editing|supervision|funding acquisition	supervision	-	Supervision	YES
6410202	30744154	C.P.	CRediT	resources|writing--review and editing|supervision|funding acquisition	funding acquisition	-	Funding acquisition	YES
6410202	30744154	F.O.	CRediT	formal analysis|writing--review and editing|visualization	formal analysis	Analyzed the data	Formal analysis	YES
6410202	30744154	F.O.	CRediT	formal analysis|writing--review and editing|visualization	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6410202	30744154	F.O.	CRediT	formal analysis|writing--review and editing|visualization	visualization	Analyzed the data	Visualization	YES
6410202	30744154	I.G.	CRediT	methodology|investigation|data curation|writing--review and editing	methodology	Performed the experiments	Methodology	YES
6410202	30744154	I.G.	CRediT	methodology|investigation|data curation|writing--review and editing	investigation	Performed the experiments	Investigation	YES
6410202	30744154	I.G.	CRediT	methodology|investigation|data curation|writing--review and editing	data curation	Analyzed the data	Data curation	YES
6410202	30744154	I.G.	CRediT	methodology|investigation|data curation|writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6410202	30744154	L.D.	CRediT	investigation|writing--review and editing	investigation	Performed the experiments	Investigation	YES
6410202	30744154	L.D.	CRediT	investigation|writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6410202	30744154	L.F.	CRediT	resources|writing--review and editing	resources	Contributed reagents/materials/analysis tools	Resources	YES
6410202	30744154	L.F.	CRediT	resources|writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6410202	30744154	L.K.	CRediT	methodology|investigation|writing--review and editing	methodology	Performed the experiments	Methodology	YES
6410202	30744154	L.K.	CRediT	methodology|investigation|writing--review and editing	investigation	Performed the experiments	Investigation	YES
6410202	30744154	L.K.	CRediT	methodology|investigation|writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6410202	30744154	M.A.D.	CRediT	Conceptualization|resources|writing--original draft preparation|writing--review and editing|supervision|funding acquisition	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6410202	30744154	M.A.D.	CRediT	Conceptualization|resources|writing--original draft preparation|writing--review and editing|supervision|funding acquisition	resources	Contributed reagents/materials/analysis tools	Resources	YES
6410202	30744154	M.A.D.	CRediT	Conceptualization|resources|writing--original draft preparation|writing--review and editing|supervision|funding acquisition	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6410202	30744154	M.A.D.	CRediT	Conceptualization|resources|writing--original draft preparation|writing--review and editing|supervision|funding acquisition	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6410202	30744154	M.A.D.	CRediT	Conceptualization|resources|writing--original draft preparation|writing--review and editing|supervision|funding acquisition	supervision	-	Supervision	YES
6410202	30744154	M.A.D.	CRediT	Conceptualization|resources|writing--original draft preparation|writing--review and editing|supervision|funding acquisition	funding acquisition	-	Funding acquisition	YES
6410202	30744154	M.V.	CRediT	investigation|writing--review and editing|funding acquisition	investigation	Performed the experiments	Investigation	YES
6410202	30744154	M.V.	CRediT	investigation|writing--review and editing|funding acquisition	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6410202	30744154	M.V.	CRediT	investigation|writing--review and editing|funding acquisition	funding acquisition	-	Funding acquisition	YES
6410202	30744154	N.I.	CRediT	resources|writing--review and editing	resources	Contributed reagents/materials/analysis tools	Resources	YES
6410202	30744154	N.I.	CRediT	resources|writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6410202	30744154	O.Z.	CRediT	investigation|writing--review and editing	investigation	Performed the experiments	Investigation	YES
6410202	30744154	O.Z.	CRediT	investigation|writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6410202	30744154	P.S.-R.	CRediT	resources|writing--review and editing|supervision	resources	Contributed reagents/materials/analysis tools	Resources	YES
6410202	30744154	P.S.-R.	CRediT	resources|writing--review and editing|supervision	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6410202	30744154	P.S.-R.	CRediT	resources|writing--review and editing|supervision	supervision	-	Supervision	YES
6410202	30744154	T.A.M.	CRediT	Conceptualization|resources|writing--review and editing|supervision|funding acquisition	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6410202	30744154	T.A.M.	CRediT	Conceptualization|resources|writing--review and editing|supervision|funding acquisition	resources	Contributed reagents/materials/analysis tools	Resources	YES
6410202	30744154	T.A.M.	CRediT	Conceptualization|resources|writing--review and editing|supervision|funding acquisition	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6410202	30744154	T.A.M.	CRediT	Conceptualization|resources|writing--review and editing|supervision|funding acquisition	supervision	-	Supervision	YES
6410202	30744154	T.A.M.	CRediT	Conceptualization|resources|writing--review and editing|supervision|funding acquisition	funding acquisition	-	Funding acquisition	YES
5443160	28596780	DS	2	generated material pertinent to this study	generated material pertinent to this study	Performed the experiments	Investigation	YES
5443160	28596780	GK	2	conducted all live cell imaging|wrote first draft of the manuscript with input from all co-authors	conducted all live cell imaging	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
5443160	28596780	GK	2	conducted all live cell imaging|wrote first draft of the manuscript with input from all co-authors	wrote first draft of the manuscript with input from all co-authors	Wrote the paper	Writing - Original Draft	YES
5443160	28596780	IL	2	generated material pertinent to this study	generated material pertinent to this study	Performed the experiments	Investigation	YES
5443160	28596780	JS	2	conceived and supervised study, helped to interpret data and finalized manuscript	conceived and supervised study, helped to interpret data and finalized manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Supervision|Writing - Review & Editing	YES
5443160	28596780	MO	2	conducted all live cell imaging|generated material pertinent to this study	conducted all live cell imaging	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
5443160	28596780	MO	2	conducted all live cell imaging|generated material pertinent to this study	generated material pertinent to this study	Performed the experiments	Investigation	YES
5443160	28596780	OS	2	helped with quantitative evaluations	helped with quantitative evaluations	-	-	NO
4398460	25875595	AB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398460	25875595	AB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398460	25875595	AB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398460	25875595	AB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398460	25875595	BD	PLoS5	Data collection, patient recruitment	Data collection, patient recruitment	Performed the experiments	Investigation	YES
4398460	25875595	DH	PLoS5	Data collection, patient recruitment	Data collection, patient recruitment	Performed the experiments	Investigation	YES
4398460	25875595	GH	PLoS5	Data collection, patient recruitment	Data collection, patient recruitment	Performed the experiments	Investigation	YES
4398460	25875595	JK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398460	25875595	JK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398460	25875595	JK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398460	25875595	JK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398460	25875595	JS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398460	25875595	JS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398460	25875595	JS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398460	25875595	LU	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398460	25875595	SD	PLoS5	Data collection, patient recruitment	Data collection, patient recruitment	Performed the experiments	Investigation	YES
4398460	25875595	SJ	PLoS5	Data collection, patient recruitment	Data collection, patient recruitment	Performed the experiments	Investigation	YES
4398460	25875595	VA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398460	25875595	VA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4398460	25875595	VA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
3562358	23374858	AFA	2	contributed to the study concept and design|conducted on-field activities|technically conducted and/or supervised the technical aspects including experiments and quality controls	contributed to the study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
3562358	23374858	AFA	2	contributed to the study concept and design|conducted on-field activities|technically conducted and/or supervised the technical aspects including experiments and quality controls	conducted on-field activities	Performed the experiments	Investigation	YES
3562358	23374858	AFA	2	contributed to the study concept and design|conducted on-field activities|technically conducted and/or supervised the technical aspects including experiments and quality controls	technically conducted and/or supervised the technical aspects including experiments and quality controls	Performed the experiments	Investigation|Supervision|Validation	YES
3562358	23374858	All	2	investigators participated in the paper writing and editing and approved the final manuscript	investigators participated in the paper writing and editing and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3562358	23374858	CB	2	conducted on-field activities	conducted on-field activities	Performed the experiments	Investigation	YES
3562358	23374858	CK	2	contributed to the study concept and design|technically conducted and/or supervised the technical aspects including experiments and quality controls	contributed to the study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
3562358	23374858	CK	2	contributed to the study concept and design|technically conducted and/or supervised the technical aspects including experiments and quality controls	technically conducted and/or supervised the technical aspects including experiments and quality controls	Performed the experiments	Investigation|Supervision|Validation	YES
3562358	23374858	CL	2	conducted on-field activities	conducted on-field activities	Performed the experiments	Investigation	YES
3562358	23374858	ED	2	contributed to the study concept and design|technically conducted and/or supervised the technical aspects including experiments and quality controls	contributed to the study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
3562358	23374858	ED	2	contributed to the study concept and design|technically conducted and/or supervised the technical aspects including experiments and quality controls	technically conducted and/or supervised the technical aspects including experiments and quality controls	Performed the experiments	Investigation|Supervision|Validation	YES
3562358	23374858	EMN	2	conducted on-field activities	conducted on-field activities	Performed the experiments	Investigation	YES
3562358	23374858	GEE	2	conducted on-field activities	conducted on-field activities	Performed the experiments	Investigation	YES
3562358	23374858	MP	2	contributed to the study concept and design|technically conducted and/or supervised the technical aspects including experiments and quality controls	contributed to the study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
3562358	23374858	MP	2	contributed to the study concept and design|technically conducted and/or supervised the technical aspects including experiments and quality controls	technically conducted and/or supervised the technical aspects including experiments and quality controls	Performed the experiments	Investigation|Supervision|Validation	YES
3562358	23374858	SED	2	technically conducted and/or supervised the technical aspects including experiments and quality controls	technically conducted and/or supervised the technical aspects including experiments and quality controls	Performed the experiments	Investigation|Supervision|Validation	YES
3562358	23374858	SKS	2	technically conducted and/or supervised the technical aspects including experiments and quality controls	technically conducted and/or supervised the technical aspects including experiments and quality controls	Performed the experiments	Investigation|Supervision|Validation	YES
4413515	25961021	All authors	2	revised the paper critically and read and approved the final version	revised the paper critically and read and approved the final version	Wrote the paper	Writing - Review & Editing	YES
4413515	25961021	Gloria P. Monterrubio-Lopez	2	performed experiments and contributed in the areas of data collection, analysis, and interpretation	performed experiments and contributed in the areas of data collection, analysis, and interpretation	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
4413515	25961021	Maria Ribas-Aparicio	2	contributed equally to the original concept and design described in the paper|supervised the overall project, providing essential guidance|drafted the paper	contributed equally to the original concept and design described in the paper	Conceived and designed the experiments	Conceptualization	YES
4413515	25961021	Maria Ribas-Aparicio	2	contributed equally to the original concept and design described in the paper|supervised the overall project, providing essential guidance|drafted the paper	supervised the overall project, providing essential guidance	-	Supervision	YES
4413515	25961021	Maria Ribas-Aparicio	2	contributed equally to the original concept and design described in the paper|supervised the overall project, providing essential guidance|drafted the paper	drafted the paper	Wrote the paper	Writing - Original Draft	YES
3106352	21660110	EB	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
3106352	21660110	EF	PLoS52	analyzed the data and elaborated the statistical calculations	analyzed the data and elaborated the statistical calculations	Analyzed the data	Formal analysis	YES
3106352	21660110	MI	PLoS52	analyzed the data and collaborated in writing the article	analyzed the data and collaborated in writing the article	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3106352	21660110	PDP	PLoS52	conceived the work, collected and analysed the data as well as collaborated in writing the article	conceived the work, collected and analysed the data as well as collaborated in writing the article	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
3106352	21660110	PZ	PLoS52	analyzed the data and collaborated in writing the article	analyzed the data and collaborated in writing the article	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5016932	27613601	CdV	2	generated the experimental data	generated the experimental data	Performed the experiments	Investigation	YES
5016932	27613601	GeR	2	designed and coordinated the study|contributed to the writing of the manuscript	designed and coordinated the study	Conceived and designed the experiments	Methodology|Project administration	YES
5016932	27613601	GeR	2	designed and coordinated the study|contributed to the writing of the manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5016932	27613601	GuR	2	designed and coordinated the study|performed the computational analysis of the data|contributed to the writing of the manuscript	designed and coordinated the study	Conceived and designed the experiments	Methodology|Project administration	YES
5016932	27613601	GuR	2	designed and coordinated the study|performed the computational analysis of the data|contributed to the writing of the manuscript	performed the computational analysis of the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5016932	27613601	GuR	2	designed and coordinated the study|performed the computational analysis of the data|contributed to the writing of the manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5016932	27613601	JK	2	generated the experimental data	generated the experimental data	Performed the experiments	Investigation	YES
5016932	27613601	JT	2	generated the experimental data	generated the experimental data	Performed the experiments	Investigation	YES
5016932	27613601	KS	2	contributed to the writing of the manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5016932	27613601	MB	2	performed the computational analysis of the data|contributed to the writing of the manuscript	performed the computational analysis of the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5016932	27613601	MB	2	performed the computational analysis of the data|contributed to the writing of the manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5016932	27613601	MKK	2	designed and coordinated the study|generated the experimental data|performed the computational analysis of the data|contributed to the writing of the manuscript	designed and coordinated the study	Conceived and designed the experiments	Methodology|Project administration	YES
5016932	27613601	MKK	2	designed and coordinated the study|generated the experimental data|performed the computational analysis of the data|contributed to the writing of the manuscript	generated the experimental data	Performed the experiments	Investigation	YES
5016932	27613601	MKK	2	designed and coordinated the study|generated the experimental data|performed the computational analysis of the data|contributed to the writing of the manuscript	performed the computational analysis of the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5016932	27613601	MKK	2	designed and coordinated the study|generated the experimental data|performed the computational analysis of the data|contributed to the writing of the manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5016932	27613601	SB	2	performed the computational analysis of the data|contributed to the writing of the manuscript	performed the computational analysis of the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5016932	27613601	SB	2	performed the computational analysis of the data|contributed to the writing of the manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5016932	27613601	SiS	2	generated the experimental data	generated the experimental data	Performed the experiments	Investigation	YES
5016932	27613601	SvS	2	performed the computational analysis of the data|contributed to the writing of the manuscript	performed the computational analysis of the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5016932	27613601	SvS	2	performed the computational analysis of the data|contributed to the writing of the manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5016932	27613601	TB	2	contributed to the writing of the manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5016932	27613601	WC	2	generated the experimental data	generated the experimental data	Performed the experiments	Investigation	YES
4398461	25875598	AF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Approved the final version of the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398461	25875598	AF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Approved the final version of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4398461	25875598	AF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Approved the final version of the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398461	25875598	AF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Approved the final version of the manuscript	Approved the final version of the manuscript	-	-	NO
4398461	25875598	AH	PLoS5	Conceived and designed the experiments|Wrote the paper|Approved the final version of the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398461	25875598	AH	PLoS5	Conceived and designed the experiments|Wrote the paper|Approved the final version of the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398461	25875598	AH	PLoS5	Conceived and designed the experiments|Wrote the paper|Approved the final version of the manuscript	Approved the final version of the manuscript	-	-	NO
4398461	25875598	AP	PLoS5	Conceived and designed the experiments|Wrote the paper|Approved the final version of the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398461	25875598	AP	PLoS5	Conceived and designed the experiments|Wrote the paper|Approved the final version of the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398461	25875598	AP	PLoS5	Conceived and designed the experiments|Wrote the paper|Approved the final version of the manuscript	Approved the final version of the manuscript	-	-	NO
4398461	25875598	CCS	PLoS5	Conceived and designed the experiments|Wrote the paper|Approved the final version of the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398461	25875598	CCS	PLoS5	Conceived and designed the experiments|Wrote the paper|Approved the final version of the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398461	25875598	CCS	PLoS5	Conceived and designed the experiments|Wrote the paper|Approved the final version of the manuscript	Approved the final version of the manuscript	-	-	NO
4398461	25875598	CR	PLoS5	Analyzed the data|Wrote the paper|Approved the final version of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4398461	25875598	CR	PLoS5	Analyzed the data|Wrote the paper|Approved the final version of the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398461	25875598	CR	PLoS5	Analyzed the data|Wrote the paper|Approved the final version of the manuscript	Approved the final version of the manuscript	-	-	NO
4398461	25875598	DP	PLoS5	Analyzed the data|Wrote the paper|Approved the final version of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4398461	25875598	DP	PLoS5	Analyzed the data|Wrote the paper|Approved the final version of the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398461	25875598	DP	PLoS5	Analyzed the data|Wrote the paper|Approved the final version of the manuscript	Approved the final version of the manuscript	-	-	NO
4398461	25875598	EK	PLoS5	Analyzed the data|Wrote the paper|Approved the final version of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4398461	25875598	EK	PLoS5	Analyzed the data|Wrote the paper|Approved the final version of the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398461	25875598	EK	PLoS5	Analyzed the data|Wrote the paper|Approved the final version of the manuscript	Approved the final version of the manuscript	-	-	NO
4398461	25875598	GKN	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Approved the final version of the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398461	25875598	GKN	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Approved the final version of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4398461	25875598	GKN	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Approved the final version of the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398461	25875598	GKN	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Approved the final version of the manuscript	Approved the final version of the manuscript	-	-	NO
4398461	25875598	JCS	PLoS5	Conceived and designed the experiments|Wrote the paper|Approved the final version of the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398461	25875598	JCS	PLoS5	Conceived and designed the experiments|Wrote the paper|Approved the final version of the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398461	25875598	JCS	PLoS5	Conceived and designed the experiments|Wrote the paper|Approved the final version of the manuscript	Approved the final version of the manuscript	-	-	NO
4398461	25875598	JES	PLoS5	Conceived and designed the experiments|Wrote the paper|Approved the final version of the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398461	25875598	JES	PLoS5	Conceived and designed the experiments|Wrote the paper|Approved the final version of the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398461	25875598	JES	PLoS5	Conceived and designed the experiments|Wrote the paper|Approved the final version of the manuscript	Approved the final version of the manuscript	-	-	NO
4398461	25875598	MD	PLoS5	Analyzed the data|Wrote the paper|Approved the final version of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4398461	25875598	MD	PLoS5	Analyzed the data|Wrote the paper|Approved the final version of the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398461	25875598	MD	PLoS5	Analyzed the data|Wrote the paper|Approved the final version of the manuscript	Approved the final version of the manuscript	-	-	NO
4398461	25875598	MMM	PLoS5	Conceived and designed the experiments|Wrote the paper|Approved the final version of the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398461	25875598	MMM	PLoS5	Conceived and designed the experiments|Wrote the paper|Approved the final version of the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398461	25875598	MMM	PLoS5	Conceived and designed the experiments|Wrote the paper|Approved the final version of the manuscript	Approved the final version of the manuscript	-	-	NO
4398461	25875598	SRF	PLoS5	Conceived and designed the experiments|Wrote the paper|Approved the final version of the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398461	25875598	SRF	PLoS5	Conceived and designed the experiments|Wrote the paper|Approved the final version of the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398461	25875598	SRF	PLoS5	Conceived and designed the experiments|Wrote the paper|Approved the final version of the manuscript	Approved the final version of the manuscript	-	-	NO
4398461	25875598	VS	PLoS5	Analyzed the data|Wrote the paper|Approved the final version of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4398461	25875598	VS	PLoS5	Analyzed the data|Wrote the paper|Approved the final version of the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398461	25875598	VS	PLoS5	Analyzed the data|Wrote the paper|Approved the final version of the manuscript	Approved the final version of the manuscript	-	-	NO
3564972	23394900	All authors	2	were involved in on-going discussions of the research and write-up	were involved in on-going discussions of the research and write-up	Wrote the paper	-	YES
3564972	23394900	CC	2	conceptualized the overarching community response study	conceptualized the overarching community response study	Conceived and designed the experiments	Conceptualization	YES
3564972	23394900	CN	2	managed the research and supervised data collection	managed the research and supervised data collection	Performed the experiments|Analyzed the data	Data curation|Investigation|Supervision	YES
3564972	23394900	MS	2	managed the data set, conducted the data analysis and wrote the article	managed the data set, conducted the data analysis and wrote the article	Analyzed the data|Wrote the paper	Data curation|Formal analysis|Writing - Original Draft	YES
3564972	23394900	Manicaland Project	2	which hosted this research	which hosted this research	-	-	NO
3564972	23394900	SMZ	2	conducted the interviews and supervised field teams assisting with data collection and transcription	conducted the interviews and supervised field teams assisting with data collection and transcription	Performed the experiments	Investigation|Supervision	YES
5445106	28603529	AE	2	conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5445106	28603529	AG-F	2	collected data	collected data	Performed the experiments	Investigation	YES
5445106	28603529	MLRT	2	collected data	collected data	Performed the experiments	Investigation	YES
5445106	28603529	SM	2	conceived the study|collected data|analyzed data and wrote the manuscript, with input from all other authors	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5445106	28603529	SM	2	conceived the study|collected data|analyzed data and wrote the manuscript, with input from all other authors	collected data	Performed the experiments	Investigation	YES
5445106	28603529	SM	2	conceived the study|collected data|analyzed data and wrote the manuscript, with input from all other authors	analyzed data and wrote the manuscript, with input from all other authors	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3111720	21673981	AG	2	contributed to data collection|analyzed data	contributed to data collection	Performed the experiments	Investigation	YES
3111720	21673981	AG	2	contributed to data collection|analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
3111720	21673981	AR	2	contributed to data collection	contributed to data collection	Performed the experiments	Investigation	YES
3111720	21673981	All authors	2	contributed to manuscript drafting and revision and approved the final manuscript	contributed to manuscript drafting and revision and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3111720	21673981	CMW	2	contributed to study design	contributed to study design	Conceived and designed the experiments	Methodology	YES
3111720	21673981	GSK	2	contributed to study design	contributed to study design	Conceived and designed the experiments	Methodology	YES
3111720	21673981	HJH	2	contributed to study design|contributed to data collection|wrote the analysis plan|analyzed data|was principal author of the paper, had full access to all data, and is a guarantor	contributed to study design	Conceived and designed the experiments	Methodology	YES
3111720	21673981	HJH	2	contributed to study design|contributed to data collection|wrote the analysis plan|analyzed data|was principal author of the paper, had full access to all data, and is a guarantor	contributed to data collection	Performed the experiments	Investigation	YES
3111720	21673981	HJH	2	contributed to study design|contributed to data collection|wrote the analysis plan|analyzed data|was principal author of the paper, had full access to all data, and is a guarantor	wrote the analysis plan	Wrote the paper	Writing - Original Draft	YES
3111720	21673981	HJH	2	contributed to study design|contributed to data collection|wrote the analysis plan|analyzed data|was principal author of the paper, had full access to all data, and is a guarantor	analyzed data	Analyzed the data	Formal analysis	YES
3111720	21673981	HJH	2	contributed to study design|contributed to data collection|wrote the analysis plan|analyzed data|was principal author of the paper, had full access to all data, and is a guarantor	was principal author of the paper, had full access to all data, and is a guarantor	Wrote the paper	Writing - Original Draft	YES
3111720	21673981	HK	2	contributed to study design|contributed to data collection|wrote the analysis plan	contributed to study design	Conceived and designed the experiments	Methodology	YES
3111720	21673981	HK	2	contributed to study design|contributed to data collection|wrote the analysis plan	contributed to data collection	Performed the experiments	Investigation	YES
3111720	21673981	HK	2	contributed to study design|contributed to data collection|wrote the analysis plan	wrote the analysis plan	Wrote the paper	Writing - Original Draft	YES
3111720	21673981	RZ	2	wrote the analysis plan	wrote the analysis plan	Wrote the paper	Writing - Original Draft	YES
3111720	21673981	SNW	2	contributed to study design	contributed to study design	Conceived and designed the experiments	Methodology	YES
4398462	25875675	BMF	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4398462	25875675	KMP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398462	25875675	MAS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398462	25875675	MAS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398462	25875675	MDP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398462	25875675	MDP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398462	25875675	MDP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398462	25875675	MDP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398462	25875675	MSC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4398462	25875675	MSC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398462	25875675	MU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398462	25875675	MU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398462	25875675	MU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398462	25875675	MU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398462	25875675	MU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398462	25875675	NLBZ	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4398462	25875675	SAB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398462	25875675	SAB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398462	25875675	SAB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398462	25875675	SH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398462	25875675	SS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5016959	27613513	KH	2	designed the study|collected samples and analyzed the clinical and pedigree data|performed the functional analyses|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5016959	27613513	KH	2	designed the study|collected samples and analyzed the clinical and pedigree data|performed the functional analyses|wrote the manuscript	collected samples and analyzed the clinical and pedigree data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5016959	27613513	KH	2	designed the study|collected samples and analyzed the clinical and pedigree data|performed the functional analyses|wrote the manuscript	performed the functional analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5016959	27613513	KH	2	designed the study|collected samples and analyzed the clinical and pedigree data|performed the functional analyses|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5016959	27613513	SSasaki	2	designed the study|performed the genotyping, autozygosity mapping, haplotype analysis, and cnv analysis|performed exome sequencing and analysis|performed the functional analyses|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5016959	27613513	SSasaki	2	designed the study|performed the genotyping, autozygosity mapping, haplotype analysis, and cnv analysis|performed exome sequencing and analysis|performed the functional analyses|wrote the manuscript	performed the genotyping, autozygosity mapping, haplotype analysis, and cnv analysis	Performed the experiments	Investigation	YES
5016959	27613513	SSasaki	2	designed the study|performed the genotyping, autozygosity mapping, haplotype analysis, and cnv analysis|performed exome sequencing and analysis|performed the functional analyses|wrote the manuscript	performed exome sequencing and analysis	Performed the experiments	Investigation	YES
5016959	27613513	SSasaki	2	designed the study|performed the genotyping, autozygosity mapping, haplotype analysis, and cnv analysis|performed exome sequencing and analysis|performed the functional analyses|wrote the manuscript	performed the functional analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5016959	27613513	SSasaki	2	designed the study|performed the genotyping, autozygosity mapping, haplotype analysis, and cnv analysis|performed exome sequencing and analysis|performed the functional analyses|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5016959	27613513	SSugano	2	performed exome sequencing and analysis	performed exome sequencing and analysis	Performed the experiments	Investigation	YES
5016959	27613513	TH	2	performed pathological examination	performed pathological examination	Performed the experiments	Investigation	YES
5016959	27613513	YSugimoto	2	designed the study|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5016959	27613513	YSugimoto	2	designed the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5016959	27613513	YSusuki	2	performed exome sequencing and analysis	performed exome sequencing and analysis	Performed the experiments	Investigation	YES
5016959	27613513	YY	2	designed the study|collected samples and analyzed the clinical and pedigree data	designed the study	Conceived and designed the experiments	Methodology	YES
5016959	27613513	YY	2	designed the study|collected samples and analyzed the clinical and pedigree data	collected samples and analyzed the clinical and pedigree data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6410212	30717084	D.C.H.	PLoS52	conceived and designed the experiments|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6410212	30717084	D.C.H.	PLoS52	conceived and designed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6410212	30717084	D.I.K.	PLoS52	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6410212	30717084	G.D.M.	PLoS52	conceived and designed the experiments|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6410212	30717084	G.D.M.	PLoS52	conceived and designed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6410212	30717084	H.S.	PLoS52	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6410212	30717084	J.B.K.	PLoS52	reviewed the data	reviewed the data	-	-	NO
6410212	30717084	J.H.C.	PLoS52	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6410212	30717084	J.H.P.	PLoS52	performed the experiments and analyzed the data|wrote the paper	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6410212	30717084	J.H.P.	PLoS52	performed the experiments and analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6410212	30717084	J.H.S.	PLoS52	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5978629	23279893	CRB	2	involved in critical appraisal and acquisition of data	involved in critical appraisal and acquisition of data	Performed the experiments	Investigation	YES
5978629	23279893	GA	2	involved in critical appraisal and acquisition of data	involved in critical appraisal and acquisition of data	Performed the experiments	Investigation	YES
5978629	23279893	JE	2	involved in critical appraisal and acquisition of data	involved in critical appraisal and acquisition of data	Performed the experiments	Investigation	YES
5978629	23279893	NA	2	involved in critical appraisal and acquisition of data	involved in critical appraisal and acquisition of data	Performed the experiments	Investigation	YES
5978629	23279893	RC	2	involved in critical appraisal and acquisition of data	involved in critical appraisal and acquisition of data	Performed the experiments	Investigation	YES
5978629	23279893	RH	2	involved in critical appraisal and acquisition of data	involved in critical appraisal and acquisition of data	Performed the experiments	Investigation	YES
5978629	23279893	RP	2	involved in critical appraisal and acquisition of data	involved in critical appraisal and acquisition of data	Performed the experiments	Investigation	YES
5978629	23279893	RS	2	involved in critical appraisal and acquisition of data	involved in critical appraisal and acquisition of data	Performed the experiments	Investigation	YES
5978629	23279893	SK	2	involved in critical appraisal and acquisition of data	involved in critical appraisal and acquisition of data	Performed the experiments	Investigation	YES
5978629	23279893	SL	2	involved in critical appraisal and acquisition of data	involved in critical appraisal and acquisition of data	Performed the experiments	Investigation	YES
5978629	23279893	V-T	2	involved in review concept and design|involved in analysis and interpretation of data|involved in manuscript preparation and contribution of intellectual content	involved in review concept and design	Conceived and designed the experiments	Conceptualization	YES
5978629	23279893	V-T	2	involved in review concept and design|involved in analysis and interpretation of data|involved in manuscript preparation and contribution of intellectual content	involved in analysis and interpretation of data	Analyzed the data	Formal analysis	YES
5978629	23279893	V-T	2	involved in review concept and design|involved in analysis and interpretation of data|involved in manuscript preparation and contribution of intellectual content	involved in manuscript preparation and contribution of intellectual content	Wrote the paper	Writing - Original Draft	YES
6410246	30717256	C.S.Y.	CRediT	Supervision|Writing--review & editing	Supervision	-	Supervision	YES
6410246	30717256	C.S.Y.	CRediT	Supervision|Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6410246	30717256	H.-G.C.	CRediT	Formal analysis	Formal analysis	Analyzed the data	Formal analysis	YES
6410246	30717256	H.T.N.	CRediT	Methodology	Methodology	Performed the experiments	Methodology	YES
6410246	30717256	J.B.K.	CRediT	Conceptualization|Writing--original draft	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6410246	30717256	J.B.K.	CRediT	Conceptualization|Writing--original draft	Writing--original draft	Wrote the paper	Writing - Original Draft	YES
6410246	30717256	J.O.K.	CRediT	Supervision|Writing--review & editing	Supervision	-	Supervision	YES
6410246	30717256	J.O.K.	CRediT	Supervision|Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6410246	30717256	K.T.O.	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
6410246	30717256	M.G.	CRediT	Methodology	Methodology	Performed the experiments	Methodology	YES
6410246	30717256	R.K.T.	CRediT	Data curation	Data curation	Analyzed the data	Data curation	YES
6410246	30717256	S.K.K.	CRediT	Visualization|Writing--review & editing	Visualization	Analyzed the data	Visualization	YES
6410246	30717256	S.K.K.	CRediT	Visualization|Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6410246	30717256	W.O.	CRediT	Formal analysis	Formal analysis	Analyzed the data	Formal analysis	YES
6410246	30717256	Z.C.S.	CRediT	Conceptualization|Writing--original draft	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6410246	30717256	Z.C.S.	CRediT	Conceptualization|Writing--original draft	Writing--original draft	Wrote the paper	Writing - Original Draft	YES
5445127	28603531	All authors	PLoS52	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5445127	28603531	BA	PLoS52	conceived the project|executed all the experiments|analyzed the structural data|wrote the paper	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5445127	28603531	BA	PLoS52	conceived the project|executed all the experiments|analyzed the structural data|wrote the paper	executed all the experiments	Performed the experiments	Investigation	YES
5445127	28603531	BA	PLoS52	conceived the project|executed all the experiments|analyzed the structural data|wrote the paper	analyzed the structural data	Analyzed the data	Formal analysis	YES
5445127	28603531	BA	PLoS52	conceived the project|executed all the experiments|analyzed the structural data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5445127	28603531	KM	PLoS52	helped coordinate the project	helped coordinate the project	-	Project administration	YES
5445127	28603531	LF	PLoS52	performed the phylogenetic analyses	performed the phylogenetic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5445127	28603531	OG	PLoS52	helped coordinate the project	helped coordinate the project	-	Project administration	YES
5445127	28603531	PA	PLoS52	conceived the project|wrote the paper|helped coordinate the project	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5445127	28603531	PA	PLoS52	conceived the project|wrote the paper|helped coordinate the project	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5445127	28603531	PA	PLoS52	conceived the project|wrote the paper|helped coordinate the project	helped coordinate the project	-	Project administration	YES
5445127	28603531	RC	PLoS52	helped prepare the protein crystal, collected the x-ray diffraction data and solved the protein structure|analyzed the structural data|wrote the paper	helped prepare the protein crystal, collected the x-ray diffraction data and solved the protein structure	Performed the experiments	Investigation	YES
5445127	28603531	RC	PLoS52	helped prepare the protein crystal, collected the x-ray diffraction data and solved the protein structure|analyzed the structural data|wrote the paper	analyzed the structural data	Analyzed the data	Formal analysis	YES
5445127	28603531	RC	PLoS52	helped prepare the protein crystal, collected the x-ray diffraction data and solved the protein structure|analyzed the structural data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398463	25875333	FRL	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398463	25875333	FRL	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398463	25875333	PW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398463	25875333	PW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4398463	25875333	PW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4398463	25875333	PW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398463	25875333	WHH	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398463	25875333	WHH	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398463	25875333	YXL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398463	25875333	YXL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398463	25875333	YXL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3564973	23374857	JMSJR	2	conceived this study, participated in its design, performed the statistical analysis and drafted the manuscript	conceived this study, participated in its design, performed the statistical analysis and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
3564973	23374857	SSS	2	conceived this study, participated in its design, performed the statistical analysis and drafted the manuscript	conceived this study, participated in its design, performed the statistical analysis and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
3985768	24803724	G.K.D.	2	contributed equally	contributed equally	-	-	NO
3985768	24803724	L.S.	2	contributed equally	contributed equally	-	-	NO
6410276	30795565	A.U.	CRediT	Conceptualization|writing--review and editing|funding acquisition	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6410276	30795565	A.U.	CRediT	Conceptualization|writing--review and editing|funding acquisition	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6410276	30795565	A.U.	CRediT	Conceptualization|writing--review and editing|funding acquisition	funding acquisition	-	Funding acquisition	YES
6410276	30795565	E.M.	CRediT	Conceptualization|methodology|writing--review and editing|supervision|funding acquisition	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6410276	30795565	E.M.	CRediT	Conceptualization|methodology|writing--review and editing|supervision|funding acquisition	methodology	Performed the experiments	Methodology	YES
6410276	30795565	E.M.	CRediT	Conceptualization|methodology|writing--review and editing|supervision|funding acquisition	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6410276	30795565	E.M.	CRediT	Conceptualization|methodology|writing--review and editing|supervision|funding acquisition	supervision	-	Supervision	YES
6410276	30795565	E.M.	CRediT	Conceptualization|methodology|writing--review and editing|supervision|funding acquisition	funding acquisition	-	Funding acquisition	YES
6410276	30795565	J.v.d.D.	CRediT	investigation	investigation	Performed the experiments	Investigation	YES
6410276	30795565	L.-S.K.	CRediT	Conceptualization|methodology|validation|formal analysis|investigation|data curation|writing--original draft preparation|visualization|funding acquisition	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6410276	30795565	L.-S.K.	CRediT	Conceptualization|methodology|validation|formal analysis|investigation|data curation|writing--original draft preparation|visualization|funding acquisition	methodology	Performed the experiments	Methodology	YES
6410276	30795565	L.-S.K.	CRediT	Conceptualization|methodology|validation|formal analysis|investigation|data curation|writing--original draft preparation|visualization|funding acquisition	validation	Performed the experiments	Validation	YES
6410276	30795565	L.-S.K.	CRediT	Conceptualization|methodology|validation|formal analysis|investigation|data curation|writing--original draft preparation|visualization|funding acquisition	formal analysis	Analyzed the data	Formal analysis	YES
6410276	30795565	L.-S.K.	CRediT	Conceptualization|methodology|validation|formal analysis|investigation|data curation|writing--original draft preparation|visualization|funding acquisition	investigation	Performed the experiments	Investigation	YES
6410276	30795565	L.-S.K.	CRediT	Conceptualization|methodology|validation|formal analysis|investigation|data curation|writing--original draft preparation|visualization|funding acquisition	data curation	Analyzed the data	Data curation	YES
6410276	30795565	L.-S.K.	CRediT	Conceptualization|methodology|validation|formal analysis|investigation|data curation|writing--original draft preparation|visualization|funding acquisition	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6410276	30795565	L.-S.K.	CRediT	Conceptualization|methodology|validation|formal analysis|investigation|data curation|writing--original draft preparation|visualization|funding acquisition	visualization	Analyzed the data	Visualization	YES
6410276	30795565	L.-S.K.	CRediT	Conceptualization|methodology|validation|formal analysis|investigation|data curation|writing--original draft preparation|visualization|funding acquisition	funding acquisition	-	Funding acquisition	YES
6410276	30795565	W.E.H.	CRediT	writing--review and editing|supervision|funding acquisition	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6410276	30795565	W.E.H.	CRediT	writing--review and editing|supervision|funding acquisition	supervision	-	Supervision	YES
6410276	30795565	W.E.H.	CRediT	writing--review and editing|supervision|funding acquisition	funding acquisition	-	Funding acquisition	YES
3568174	23394899	All the authors	2	were involved in the conception and design of the project of which this paper is an outcome|have critically reviewed various drafts and have approved the final version submitted for publication	were involved in the conception and design of the project of which this paper is an outcome	Conceived and designed the experiments	Conceptualization|Methodology	YES
3568174	23394899	All the authors	2	were involved in the conception and design of the project of which this paper is an outcome|have critically reviewed various drafts and have approved the final version submitted for publication	have critically reviewed various drafts and have approved the final version submitted for publication	Wrote the paper	Writing - Original Draft	YES
4398464	25874910	EC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398464	25874910	EC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398464	25874910	EC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398464	25874910	JDL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398464	25874910	JDL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398464	25874910	JDL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398464	25874910	KC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398464	25874910	KC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398464	25874910	KC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398464	25874910	KH	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398464	25874910	KH	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398464	25874910	MJL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398464	25874910	MJL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398464	25874910	MJL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398464	25874910	TM	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398464	25874910	TM	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5020489	27619017	DBW	2	designed the study, conducted the analyses and wrote the manuscript	designed the study, conducted the analyses and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5020489	27619017	DP	2	designed the study, conducted the analyses and wrote the manuscript	designed the study, conducted the analyses and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5020489	27619017	RLT	2	designed the study and wrote the manuscript	designed the study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5445130	28603530	AT	2	were involved in collection and assembly of data|were involved in the analysis and interpretation of the data	were involved in collection and assembly of data	Performed the experiments	Investigation	YES
5445130	28603530	AT	2	were involved in collection and assembly of data|were involved in the analysis and interpretation of the data	were involved in the analysis and interpretation of the data	Analyzed the data	Formal analysis	YES
5445130	28603530	All authors	2	were involved in the drafting of this article|were involved in final approval of the article	were involved in the drafting of this article	Wrote the paper	Writing - Original Draft	YES
5445130	28603530	All authors	2	were involved in the drafting of this article|were involved in final approval of the article	were involved in final approval of the article	-	-	NO
5445130	28603530	CM	2	were involved in the conception and design of this project|were involved in collection and assembly of data|were involved in the analysis and interpretation of the data|were responsible for critical revision of the article for important intellectual content	were involved in the conception and design of this project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5445130	28603530	CM	2	were involved in the conception and design of this project|were involved in collection and assembly of data|were involved in the analysis and interpretation of the data|were responsible for critical revision of the article for important intellectual content	were involved in collection and assembly of data	Performed the experiments	Investigation	YES
5445130	28603530	CM	2	were involved in the conception and design of this project|were involved in collection and assembly of data|were involved in the analysis and interpretation of the data|were responsible for critical revision of the article for important intellectual content	were involved in the analysis and interpretation of the data	Analyzed the data	Formal analysis	YES
5445130	28603530	CM	2	were involved in the conception and design of this project|were involved in collection and assembly of data|were involved in the analysis and interpretation of the data|were responsible for critical revision of the article for important intellectual content	were responsible for critical revision of the article for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5445130	28603530	CZ	2	were involved in collection and assembly of data|were involved in the analysis and interpretation of the data	were involved in collection and assembly of data	Performed the experiments	Investigation	YES
5445130	28603530	CZ	2	were involved in collection and assembly of data|were involved in the analysis and interpretation of the data	were involved in the analysis and interpretation of the data	Analyzed the data	Formal analysis	YES
5445130	28603530	DY	2	were involved in collection and assembly of data	were involved in collection and assembly of data	Performed the experiments	Investigation	YES
5445130	28603530	GP	2	were involved in the conception and design of this project|were involved in the analysis and interpretation of the data|were responsible for critical revision of the article for important intellectual content	were involved in the conception and design of this project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5445130	28603530	GP	2	were involved in the conception and design of this project|were involved in the analysis and interpretation of the data|were responsible for critical revision of the article for important intellectual content	were involved in the analysis and interpretation of the data	Analyzed the data	Formal analysis	YES
5445130	28603530	GP	2	were involved in the conception and design of this project|were involved in the analysis and interpretation of the data|were responsible for critical revision of the article for important intellectual content	were responsible for critical revision of the article for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5445130	28603530	HS	2	were involved in the conception and design of this project|were involved in the analysis and interpretation of the data|were responsible for critical revision of the article for important intellectual content	were involved in the conception and design of this project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5445130	28603530	HS	2	were involved in the conception and design of this project|were involved in the analysis and interpretation of the data|were responsible for critical revision of the article for important intellectual content	were involved in the analysis and interpretation of the data	Analyzed the data	Formal analysis	YES
5445130	28603530	HS	2	were involved in the conception and design of this project|were involved in the analysis and interpretation of the data|were responsible for critical revision of the article for important intellectual content	were responsible for critical revision of the article for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5445130	28603530	JD	2	were involved in collection and assembly of data|were responsible for critical revision of the article for important intellectual content	were involved in collection and assembly of data	Performed the experiments	Investigation	YES
5445130	28603530	JD	2	were involved in collection and assembly of data|were responsible for critical revision of the article for important intellectual content	were responsible for critical revision of the article for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5445130	28603530	JM	2	were involved in the conception and design of this project|were involved in the analysis and interpretation of the data|were responsible for critical revision of the article for important intellectual content	were involved in the conception and design of this project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5445130	28603530	JM	2	were involved in the conception and design of this project|were involved in the analysis and interpretation of the data|were responsible for critical revision of the article for important intellectual content	were involved in the analysis and interpretation of the data	Analyzed the data	Formal analysis	YES
5445130	28603530	JM	2	were involved in the conception and design of this project|were involved in the analysis and interpretation of the data|were responsible for critical revision of the article for important intellectual content	were responsible for critical revision of the article for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5445130	28603530	NK	2	were involved in collection and assembly of data	were involved in collection and assembly of data	Performed the experiments	Investigation	YES
5445130	28603530	SJ	2	were involved in collection and assembly of data	were involved in collection and assembly of data	Performed the experiments	Investigation	YES
6410284	30691199	M.J.T.	2	conducted part of the experiments and contributed to discussions	conducted part of the experiments and contributed to discussions	Performed the experiments	Investigation	YES
6410284	30691199	M.W.J.	2	is the main author of the manuscript|planned and conducted most of the experiments and significantly contributed to the manuscript preparation	is the main author of the manuscript	Wrote the paper	Writing - Original Draft	YES
6410284	30691199	M.W.J.	2	is the main author of the manuscript|planned and conducted most of the experiments and significantly contributed to the manuscript preparation	planned and conducted most of the experiments and significantly contributed to the manuscript preparation	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
6410284	30691199	N.S.-B.	2	is the project leader and supervised the presented work, as well as the manuscript preparation	is the project leader and supervised the presented work, as well as the manuscript preparation	Wrote the paper	Supervision|Writing - Original Draft	YES
6410284	30691199	P.B.	2	planned and supervised all cell experiments and contributed to the relevant discussions on findings	planned and supervised all cell experiments and contributed to the relevant discussions on findings	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Supervision	YES
6410284	30691199	S.M.	2	conducted part of the experiments and contributed to discussions	conducted part of the experiments and contributed to discussions	Performed the experiments	Investigation	YES
4398465	25875177	AR	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398465	25875177	AR	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398465	25875177	AR	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398465	25875177	IK	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398465	25875177	IK	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398465	25875177	IK	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398465	25875177	JJLC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398465	25875177	JJLC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398465	25875177	JJLC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398465	25875177	PW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398465	25875177	PW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398465	25875177	PW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398465	25875177	PW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3568677	23394898	BJP	PLoS52	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
3568677	23394898	TJA	PLoS52	designed the study|undertook fieldwork and data collection|analyzed the data	designed the study	Conceived and designed the experiments	Methodology	YES
3568677	23394898	TJA	PLoS52	designed the study|undertook fieldwork and data collection|analyzed the data	undertook fieldwork and data collection	Performed the experiments	Investigation	YES
3568677	23394898	TJA	PLoS52	designed the study|undertook fieldwork and data collection|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
3568677	23394898	TME	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5758678	29090397	AC	2	assisted drafting the qualitative analysis|drafted and reviewed sections of the article	assisted drafting the qualitative analysis	Wrote the paper	Writing - Original Draft	YES
5758678	29090397	AC	2	assisted drafting the qualitative analysis|drafted and reviewed sections of the article	drafted and reviewed sections of the article	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5758678	29090397	CK	2	drafted the article|conducted the qualitative analysis	drafted the article	Wrote the paper	Writing - Original Draft	YES
5758678	29090397	CK	2	drafted the article|conducted the qualitative analysis	conducted the qualitative analysis	Performed the experiments	Investigation	YES
5758678	29090397	DO	2	conducted the qualitative analysis	conducted the qualitative analysis	Performed the experiments	Investigation	YES
5758678	29090397	EK	2	reviewed findings for accuracy in fieldwork	reviewed findings for accuracy in fieldwork	Performed the experiments	Investigation	YES
5758678	29090397	EM	2	drafted and reviewed sections of the article	drafted and reviewed sections of the article	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5758678	29090397	KC	2	drafted and reviewed sections of the article	drafted and reviewed sections of the article	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5758678	29090397	MB	2	assisted drafting the qualitative analysis|drafted and reviewed sections of the article	assisted drafting the qualitative analysis	Wrote the paper	Writing - Original Draft	YES
5758678	29090397	MB	2	assisted drafting the qualitative analysis|drafted and reviewed sections of the article	drafted and reviewed sections of the article	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5758678	29090397	MD	2	assisted drafting the qualitative analysis	assisted drafting the qualitative analysis	Wrote the paper	Writing - Original Draft	YES
5758678	29090397	MN	2	reviewed findings for accuracy in fieldwork	reviewed findings for accuracy in fieldwork	Performed the experiments	Investigation	YES
5758678	29090397	MP	2	drafted the article|conducted the qualitative analysis	drafted the article	Wrote the paper	Writing - Original Draft	YES
5758678	29090397	MP	2	drafted the article|conducted the qualitative analysis	conducted the qualitative analysis	Performed the experiments	Investigation	YES
5758678	29090397	RK	2	drafted and reviewed sections of the article	drafted and reviewed sections of the article	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5758678	29090397	VW	2	drafted and reviewed sections of the article	drafted and reviewed sections of the article	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5758678	29090397	WM	2	drafted and reviewed sections of the article	drafted and reviewed sections of the article	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5022155	27624183	CAL	2	conceived and designed the study, coordinated the research and participated in the drafting of the manuscript	conceived and designed the study, coordinated the research and participated in the drafting of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
5022155	27624183	CDN	2	helped with sampling and interpretation	helped with sampling and interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5022155	27624183	KVK	2	conceived and designed the study, coordinated the research and participated in the drafting of the manuscript	conceived and designed the study, coordinated the research and participated in the drafting of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
5022155	27624183	ML	2	performed the sequence data mining and analysis, snps genotyping and wrote the manuscript	performed the sequence data mining and analysis, snps genotyping and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5022155	27624183	TDB	2	helped with sampling and interpretation	helped with sampling and interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5022155	27624183	TEK	2	participated in the probe design and helped with data analysis	participated in the probe design and helped with data analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis	YES
5445156	28603539	Both authors	2	approved it for publication	approved it for publication	-	-	NO
5445156	28603539	JE	2	initiated this research topic|revised and prepared the final version	initiated this research topic	Conceived and designed the experiments	Conceptualization	YES
5445156	28603539	JE	2	initiated this research topic|revised and prepared the final version	revised and prepared the final version	Wrote the paper	Writing - Review & Editing	YES
5445156	28603539	RS	2	revised and prepared the final version	revised and prepared the final version	Wrote the paper	Writing - Review & Editing	YES
4398466	25874388	HdP	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398466	25874388	MDN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398466	25874388	MDN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398466	25874388	MDN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398466	25874388	MDN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398466	25874388	S. Helm	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398466	25874388	S. Helm	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4398466	25874388	S. Helm	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4398466	25874388	S. Horstmann	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398466	25874388	SK	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398466	25874388	SK	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398466	25874388	TA	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398466	25874388	TA	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398466	25874388	VH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398466	25874388	VH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398466	25874388	VH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6202675	30196989	All authors	2	have agreed to the final version of the manuscript	have agreed to the final version of the manuscript	-	-	NO
6202675	30196989	C.v.W.	2	conceived the study|contributed to the data analysis	conceived the study	Conceived and designed the experiments	Conceptualization	YES
6202675	30196989	C.v.W.	2	conceived the study|contributed to the data analysis	contributed to the data analysis	Analyzed the data	Formal analysis	YES
6202675	30196989	G.B.	2	contributed to the data analysis	contributed to the data analysis	Analyzed the data	Formal analysis	YES
6202675	30196989	S.S.	2	contributed to the data analysis	contributed to the data analysis	Analyzed the data	Formal analysis	YES
6202675	30196989	Y.H.	2	conceived the study|contributed to the data analysis|completed the first draft of the manuscript, and all other authors have contributed to the further documents	conceived the study	Conceived and designed the experiments	Conceptualization	YES
6202675	30196989	Y.H.	2	conceived the study|contributed to the data analysis|completed the first draft of the manuscript, and all other authors have contributed to the further documents	contributed to the data analysis	Analyzed the data	Formal analysis	YES
6202675	30196989	Y.H.	2	conceived the study|contributed to the data analysis|completed the first draft of the manuscript, and all other authors have contributed to the further documents	completed the first draft of the manuscript, and all other authors have contributed to the further documents	Wrote the paper	Writing - Original Draft	YES
5025555	27633377	All authors	PLoS52	analysed the data and contributed to the manuscript preparation	analysed the data and contributed to the manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5025555	27633377	FL	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5025555	27633377	HC	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5025555	27633377	HL	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5025555	27633377	SW	PLoS52	designed all experiments	designed all experiments	Conceived and designed the experiments	Methodology	YES
5025555	27633377	WS	PLoS52	conceived the project|designed all experiments|wrote the manuscript	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5025555	27633377	WS	PLoS52	conceived the project|designed all experiments|wrote the manuscript	designed all experiments	Conceived and designed the experiments	Methodology	YES
5025555	27633377	WS	PLoS52	conceived the project|designed all experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5025555	27633377	XB	PLoS52	designed all experiments	designed all experiments	Conceived and designed the experiments	Methodology	YES
3572217	23406964	LS	2	was the sole author for the manuscript	was the sole author for the manuscript	-	-	NO
6470475	30857331	A.M.A.-S.	CRediT	Conceptualization|methodology|formal analysis|data curation|writing--original draft preparation|funding acquisition	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6470475	30857331	A.M.A.-S.	CRediT	Conceptualization|methodology|formal analysis|data curation|writing--original draft preparation|funding acquisition	methodology	Performed the experiments	Methodology	YES
6470475	30857331	A.M.A.-S.	CRediT	Conceptualization|methodology|formal analysis|data curation|writing--original draft preparation|funding acquisition	formal analysis	Analyzed the data	Formal analysis	YES
6470475	30857331	A.M.A.-S.	CRediT	Conceptualization|methodology|formal analysis|data curation|writing--original draft preparation|funding acquisition	data curation	Analyzed the data	Data curation	YES
6470475	30857331	A.M.A.-S.	CRediT	Conceptualization|methodology|formal analysis|data curation|writing--original draft preparation|funding acquisition	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6470475	30857331	A.M.A.-S.	CRediT	Conceptualization|methodology|formal analysis|data curation|writing--original draft preparation|funding acquisition	funding acquisition	-	Funding acquisition	YES
6470475	30857331	J.R.V.-B.	CRediT	resources|writing--review and editing|project administration|funding acquisition	resources	Contributed reagents/materials/analysis tools	Resources	YES
6470475	30857331	J.R.V.-B.	CRediT	resources|writing--review and editing|project administration|funding acquisition	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6470475	30857331	J.R.V.-B.	CRediT	resources|writing--review and editing|project administration|funding acquisition	project administration	-	Project administration	YES
6470475	30857331	J.R.V.-B.	CRediT	resources|writing--review and editing|project administration|funding acquisition	funding acquisition	-	Funding acquisition	YES
6470475	30857331	M.N.-H.	CRediT	resources|writing--review and editing|project administration|funding acquisition	resources	Contributed reagents/materials/analysis tools	Resources	YES
6470475	30857331	M.N.-H.	CRediT	resources|writing--review and editing|project administration|funding acquisition	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6470475	30857331	M.N.-H.	CRediT	resources|writing--review and editing|project administration|funding acquisition	project administration	-	Project administration	YES
6470475	30857331	M.N.-H.	CRediT	resources|writing--review and editing|project administration|funding acquisition	funding acquisition	-	Funding acquisition	YES
6470475	30857331	S.L.C.	CRediT	Conceptualization|methodology|writing--review and editing|supervision	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6470475	30857331	S.L.C.	CRediT	Conceptualization|methodology|writing--review and editing|supervision	methodology	Performed the experiments	Methodology	YES
6470475	30857331	S.L.C.	CRediT	Conceptualization|methodology|writing--review and editing|supervision	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6470475	30857331	S.L.C.	CRediT	Conceptualization|methodology|writing--review and editing|supervision	supervision	-	Supervision	YES
6470475	30857331	T.G.-G.	CRediT	resources|writing--review and editing|supervision|project administration|funding acquisition	resources	Contributed reagents/materials/analysis tools	Resources	YES
6470475	30857331	T.G.-G.	CRediT	resources|writing--review and editing|supervision|project administration|funding acquisition	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6470475	30857331	T.G.-G.	CRediT	resources|writing--review and editing|supervision|project administration|funding acquisition	supervision	-	Supervision	YES
6470475	30857331	T.G.-G.	CRediT	resources|writing--review and editing|supervision|project administration|funding acquisition	project administration	-	Project administration	YES
6470475	30857331	T.G.-G.	CRediT	resources|writing--review and editing|supervision|project administration|funding acquisition	funding acquisition	-	Funding acquisition	YES
3988683	24748722	D.S.	2	contributed equally	contributed equally	-	-	NO
3988683	24748722	H.C.	2	contributed equally	contributed equally	-	-	NO
4398478	25876033	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398478	25876033	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398478	25876033	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398478	25876033	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398478	25876033	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398478	25876033	WCS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398478	25876033	WCS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398478	25876033	WCS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398478	25876033	WCS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398478	25876033	WCS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5758696	28063075	AM	2	provided overall study guidance	provided overall study guidance	-	Supervision	YES
5758696	28063075	All authors	2	have commented on drafts of the manuscript and approved the final version	have commented on drafts of the manuscript and approved the final version	Wrote the paper	Writing - Original Draft	YES
5758696	28063075	CC	2	conceived the design of the study|helped write the second draft|analysed data and reviewed the academic literature|provided overall study guidance	conceived the design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5758696	28063075	CC	2	conceived the design of the study|helped write the second draft|analysed data and reviewed the academic literature|provided overall study guidance	helped write the second draft	Wrote the paper	Writing - Original Draft	YES
5758696	28063075	CC	2	conceived the design of the study|helped write the second draft|analysed data and reviewed the academic literature|provided overall study guidance	analysed data and reviewed the academic literature	Analyzed the data	Formal analysis	YES
5758696	28063075	CC	2	conceived the design of the study|helped write the second draft|analysed data and reviewed the academic literature|provided overall study guidance	provided overall study guidance	-	Supervision	YES
5758696	28063075	DC	2	helped write the second draft|provided overall study guidance	helped write the second draft	Wrote the paper	Writing - Original Draft	YES
5758696	28063075	DC	2	helped write the second draft|provided overall study guidance	provided overall study guidance	-	Supervision	YES
5758696	28063075	ES	2	collected data	collected data	Performed the experiments	Investigation	YES
5758696	28063075	JM	2	provided overall study guidance	provided overall study guidance	-	Supervision	YES
5758696	28063075	KM	2	helped write the second draft|analysed data and reviewed the academic literature	helped write the second draft	Wrote the paper	Writing - Original Draft	YES
5758696	28063075	KM	2	helped write the second draft|analysed data and reviewed the academic literature	analysed data and reviewed the academic literature	Analyzed the data	Formal analysis	YES
5758696	28063075	MA	2	wrote the first draft of the manuscript|collected data|analysed data and reviewed the academic literature	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
5758696	28063075	MA	2	wrote the first draft of the manuscript|collected data|analysed data and reviewed the academic literature	collected data	Performed the experiments	Investigation	YES
5758696	28063075	MA	2	wrote the first draft of the manuscript|collected data|analysed data and reviewed the academic literature	analysed data and reviewed the academic literature	Analyzed the data	Formal analysis	YES
5758696	28063075	NC	2	helped write the second draft|analysed data and reviewed the academic literature	helped write the second draft	Wrote the paper	Writing - Original Draft	YES
5758696	28063075	NC	2	helped write the second draft|analysed data and reviewed the academic literature	analysed data and reviewed the academic literature	Analyzed the data	Formal analysis	YES
5758696	28063075	NM	2	collected data	collected data	Performed the experiments	Investigation	YES
5758696	28063075	PN	2	helped write the second draft|collected data	helped write the second draft	Wrote the paper	Writing - Original Draft	YES
5758696	28063075	PN	2	helped write the second draft|collected data	collected data	Performed the experiments	Investigation	YES
5758696	28063075	SS	2	conceived the design of the study	conceived the design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5758696	28063075	TB	2	collected data	collected data	Performed the experiments	Investigation	YES
5758696	28063075	VS	2	analysed data and reviewed the academic literature	analysed data and reviewed the academic literature	Analyzed the data	Formal analysis	YES
5758696	28063075	WM	2	collected data|provided overall study guidance	collected data	Performed the experiments	Investigation	YES
5758696	28063075	WM	2	collected data|provided overall study guidance	provided overall study guidance	-	Supervision	YES
5445162	28603535	HJ	2	conducted fieldwork	conducted fieldwork	Performed the experiments	Investigation	YES
5445162	28603535	HW	2	conducted fieldwork	conducted fieldwork	Performed the experiments	Investigation	YES
5445162	28603535	PL	2	conducted fieldwork	conducted fieldwork	Performed the experiments	Investigation	YES
5445162	28603535	SN	2	conducted fieldwork	conducted fieldwork	Performed the experiments	Investigation	YES
5445162	28603535	YC	2	developed methodology|performed statistical analyses and wrote the manuscript	developed methodology	Performed the experiments	Methodology	YES
5445162	28603535	YC	2	developed methodology|performed statistical analyses and wrote the manuscript	performed statistical analyses and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5445162	28603535	YY	2	conducted fieldwork	conducted fieldwork	Performed the experiments	Investigation	YES
5445162	28603535	ZY	2	originally formulated the idea	originally formulated the idea	Conceived and designed the experiments	Conceptualization	YES
3574170	23406965	All authors	2	have read and approved the final version	have read and approved the final version	-	-	NO
3574170	23406965	CG	2	contributed to take the hpv cervical samples during gynaecological examinations of the patients and to critical revision of the manuscript	contributed to take the hpv cervical samples during gynaecological examinations of the patients and to critical revision of the manuscript	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Resources|Writing - Review & Editing	YES
3574170	23406965	DK	2	contributed to conceptualization of the study, acquisition of the data, interpretation of the data, drafting, revising and final approval of the manuscript	contributed to conceptualization of the study, acquisition of the data, interpretation of the data, drafting, revising and final approval of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
3574170	23406965	DL	2	contributed to analysis the cytology and histology of the cervical samples and to critical revision of the manuscript	contributed to analysis the cytology and histology of the cervical samples and to critical revision of the manuscript	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Resources|Writing - Review & Editing	YES
3574170	23406965	FF	2	contributed to analysis the cytology and histology of the cervical samples and to critical revision of the manuscript	contributed to analysis the cytology and histology of the cervical samples and to critical revision of the manuscript	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Resources|Writing - Review & Editing	YES
3574170	23406965	JdM	2	contributed to perfom hybrid captur analysis and to critical revision of the manuscript	contributed to perfom hybrid captur analysis and to critical revision of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
3574170	23406965	MD	2	contributed to build the database, to perform the statistical analysis and to critical revision of the manuscript	contributed to build the database, to perform the statistical analysis and to critical revision of the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Software|Writing - Review & Editing	YES
3574170	23406965	NC	2	contributed to conceptualization of the study, interpretation of the data, to critical revision and final approval of the manuscript	contributed to conceptualization of the study, interpretation of the data, to critical revision and final approval of the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Resources|Writing - Review & Editing	YES
3574170	23406965	PB	2	contributed to take the hpv cervical samples during gynaecological examinations of the patients and to critical revision of the manuscript	contributed to take the hpv cervical samples during gynaecological examinations of the patients and to critical revision of the manuscript	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Resources|Writing - Review & Editing	YES
3574170	23406965	SDW	2	contributed to conceptualization of the study, interpretation of the data, to critical revision and final approval of the manuscript	contributed to conceptualization of the study, interpretation of the data, to critical revision and final approval of the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Resources|Writing - Review & Editing	YES
3574170	23406965	YM	2	contributed to take the hpv cervical samples during gynaecological examinations of the patients and to critical revision of the manuscript	contributed to take the hpv cervical samples during gynaecological examinations of the patients and to critical revision of the manuscript	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Resources|Writing - Review & Editing	YES
6470535	30866418	A.M.	2	performed the experiments as part of his msc degree, analyzed the data and wrote the article	performed the experiments as part of his msc degree, analyzed the data and wrote the article	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6470535	30866418	R.B.W.	2	contributed to the bibliographical research and proof reading	contributed to the bibliographical research and proof reading	-	Formal analysis	YES
6470535	30866418	S.M.M.K.	2	supervised, conceptualized the project, introduced the use of design of experiments ann and analyzed the data	supervised, conceptualized the project, introduced the use of design of experiments ann and analyzed the data	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology|Supervision	YES
5025611	27634541	AA	2	conceived of the study, and participated in its design and helped to draft the manuscript	conceived of the study, and participated in its design and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
5025611	27634541	AH	2	carried out the systematic methodology	carried out the systematic methodology	Performed the experiments	Investigation|Methodology	YES
5025611	27634541	AN	2	participated in analysis of results and drafting of the manuscript	participated in analysis of results and drafting of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5025611	27634541	AO	2	participated in analysis and drafting of the manuscript	participated in analysis and drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
5025611	27634541	FMA	2	participated in drafting of the manuscript	participated in drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
5025611	27634541	HAJ	2	contributed in the critical revision of the manuscript	contributed in the critical revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5025611	27634541	JA	2	participated in drafting of the manuscript	participated in drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
5025611	27634541	KN	2	participated in the analysis and interpretation of the results	participated in the analysis and interpretation of the results	Analyzed the data	Formal analysis	YES
5025611	27634541	RZP	2	participated in drafting of the manuscript	participated in drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
5025611	27634541	SAM	2	helped in drafting of the manuscript	helped in drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
4398479	25874798	MWB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398479	25874798	MWB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398479	25874798	MWB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398479	25874798	MWB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398479	25874798	RAP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398479	25874798	RAP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398479	25874798	RAP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398479	25874798	XEB	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398479	25874798	XEB	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4208687	23895457	All authors	2	were involved in the conception, design, writing and final approval of the manuscript	were involved in the conception, design, writing and final approval of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4414229	25961013	Hongwu Wang	2	performed the mathematical models and methods of this study	performed the mathematical models and methods of this study	Performed the experiments	Formal analysis|Investigation|Methodology	YES
4414229	25961013	Hongyu Liu	2	validated health information for all subjects	validated health information for all subjects	Performed the experiments	Validation	YES
4414229	25961013	Liqun Yin	2	validated health information for all subjects	validated health information for all subjects	Performed the experiments	Validation	YES
4414229	25961013	Wenhua Wang	2	validated health information for all subjects	validated health information for all subjects	Performed the experiments	Validation	YES
4299403	25620849	All authors	2	have given approval to the final version of the manuscript	have given approval to the final version of the manuscript	-	-	NO
5818562	28439755	AM	PLoS5	Conceived and designed the study|Contributed materials/analysis tools	Conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5818562	28439755	AM	PLoS5	Conceived and designed the study|Contributed materials/analysis tools	Contributed materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5818562	28439755	All authors	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5818562	28439755	All authors	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5818562	28439755	CG	PLoS5	Conducted the study|Contributed materials/analysis tools	Conducted the study	Performed the experiments	Investigation	YES
5818562	28439755	CG	PLoS5	Conducted the study|Contributed materials/analysis tools	Contributed materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5818562	28439755	CJ	PLoS5	Conducted the study|Contributed materials/analysis tools	Conducted the study	Performed the experiments	Investigation	YES
5818562	28439755	CJ	PLoS5	Conducted the study|Contributed materials/analysis tools	Contributed materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5818562	28439755	DG	PLoS5	Conceived and designed the study|Conducted the study|Contributed materials/analysis tools	Conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5818562	28439755	DG	PLoS5	Conceived and designed the study|Conducted the study|Contributed materials/analysis tools	Conducted the study	Performed the experiments	Investigation	YES
5818562	28439755	DG	PLoS5	Conceived and designed the study|Conducted the study|Contributed materials/analysis tools	Contributed materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5818562	28439755	JK	PLoS5	Conceived and designed the study|Conducted the study|Contributed materials/analysis tools	Conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5818562	28439755	JK	PLoS5	Conceived and designed the study|Conducted the study|Contributed materials/analysis tools	Conducted the study	Performed the experiments	Investigation	YES
5818562	28439755	JK	PLoS5	Conceived and designed the study|Conducted the study|Contributed materials/analysis tools	Contributed materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5818562	28439755	MS	PLoS5	Conceived and designed the study|Conducted the study|Conducted the study|Contributed materials/analysis tools	Conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5818562	28439755	MS	PLoS5	Conceived and designed the study|Conducted the study|Conducted the study|Contributed materials/analysis tools	Conducted the study	Performed the experiments	Investigation	YES
5818562	28439755	MS	PLoS5	Conceived and designed the study|Conducted the study|Conducted the study|Contributed materials/analysis tools	Conducted the study	Performed the experiments	Investigation	YES
5818562	28439755	MS	PLoS5	Conceived and designed the study|Conducted the study|Conducted the study|Contributed materials/analysis tools	Contributed materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5818562	28439755	NE	PLoS5	Conceived and designed the study|Conducted the study|Contributed materials/analysis tools	Conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5818562	28439755	NE	PLoS5	Conceived and designed the study|Conducted the study|Contributed materials/analysis tools	Conducted the study	Performed the experiments	Investigation	YES
5818562	28439755	NE	PLoS5	Conceived and designed the study|Conducted the study|Contributed materials/analysis tools	Contributed materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5818562	28439755	NL	PLoS5	Conceived and designed the study|Conducted the study	Conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5818562	28439755	NL	PLoS5	Conceived and designed the study|Conducted the study	Conducted the study	Performed the experiments	Investigation	YES
5818562	28439755	NPP	PLoS5	Conceived and designed the study|Conducted the study|Contributed materials/analysis tools	Conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5818562	28439755	NPP	PLoS5	Conceived and designed the study|Conducted the study|Contributed materials/analysis tools	Conducted the study	Performed the experiments	Investigation	YES
5818562	28439755	NPP	PLoS5	Conceived and designed the study|Conducted the study|Contributed materials/analysis tools	Contributed materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5818562	28439755	TW	PLoS5	Conducted the study|Contributed materials/analysis tools	Conducted the study	Performed the experiments	Investigation	YES
5818562	28439755	TW	PLoS5	Conducted the study|Contributed materials/analysis tools	Contributed materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5445170	28603537	MR	2	performed the gs analyses and revised the manuscript	performed the gs analyses and revised the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
5445170	28603537	MS	2	led the experiments and revised the paper and figures	led the experiments and revised the paper and figures	Wrote the paper	Visualization|Writing - Review & Editing	YES
5445170	28603537	MvW	2	conducted the qtl experiments	conducted the qtl experiments	Performed the experiments	Investigation	YES
5445170	28603537	SM	2	conducted the gs through development experiment, did all the analyses and wrote the paper	conducted the gs through development experiment, did all the analyses and wrote the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5445170	28603537	T-PN	2	revised the manuscript and helped with the qtl analyses	revised the manuscript and helped with the qtl analyses	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4398480	25874636	HM	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398480	25874636	HM	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398480	25874636	KH	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398480	25874636	KH	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398480	25874636	KH	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398480	25874636	KH	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398480	25874636	KP	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398480	25874636	MAL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398480	25874636	MAL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4398480	25874636	MAL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4398480	25874636	MK	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398480	25874636	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398480	25874636	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398480	25874636	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398480	25874636	MU	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398480	25874636	MU	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398480	25874636	SA	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398480	25874636	SA	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4398480	25874636	SA	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398480	25874636	US	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6470558	30884757	All authors	2	reviewed and approved the manuscript	reviewed and approved the manuscript	Wrote the paper	Writing - Review & Editing	YES
6470558	30884757	Guilin Chen	2	performed the research, analyzed the data, and wrote the paper	performed the research, analyzed the data, and wrote the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6470558	30884757	Guofang Chen	2	conceived and designed the research	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
6470558	30884757	J.D.	2	performed the research, analyzed the data, and wrote the paper	performed the research, analyzed the data, and wrote the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6470558	30884757	M.G.	2	conceived and designed the research	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5025612	27633252	AR	2	analysed the genome distribution of small rnas	analysed the genome distribution of small rnas	-	-	NO
5025612	27633252	BS	2	conceived the study, designed and performed the research, analysed and interpreted the data, and wrote the manuscript with input from all authors	conceived the study, designed and performed the research, analysed and interpreted the data, and wrote the manuscript with input from all authors	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5025612	27633252	MH	2	analysed and interpreted the data	analysed and interpreted the data	Analyzed the data	Formal analysis	YES
3582697	23443042	A. Shet	PLoS52	contributed with reagents/materials/analysis tools|reviewed the paper	contributed with reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
3582697	23443042	A. Shet	PLoS52	contributed with reagents/materials/analysis tools|reviewed the paper	reviewed the paper	Wrote the paper	Writing - Review & Editing	YES
3582697	23443042	A. Sonnerborg	PLoS52	conceived and designed the experiments|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
3582697	23443042	A. Sonnerborg	PLoS52	conceived and designed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3582697	23443042	ACB	PLoS52	conceived and designed the experiments|contributed with reagents/materials/analysis tools|reviewed the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
3582697	23443042	ACB	PLoS52	conceived and designed the experiments|contributed with reagents/materials/analysis tools|reviewed the paper	contributed with reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
3582697	23443042	ACB	PLoS52	conceived and designed the experiments|contributed with reagents/materials/analysis tools|reviewed the paper	reviewed the paper	Wrote the paper	Writing - Review & Editing	YES
3582697	23443042	IB	PLoS52	performed the experiments|analyzed the data|reviewed the paper	performed the experiments	Performed the experiments	Investigation	YES
3582697	23443042	IB	PLoS52	performed the experiments|analyzed the data|reviewed the paper	analyzed the data	Analyzed the data	Formal analysis	YES
3582697	23443042	IB	PLoS52	performed the experiments|analyzed the data|reviewed the paper	reviewed the paper	Wrote the paper	Writing - Review & Editing	YES
3582697	23443042	MLE	PLoS52	contributed with reagents/materials/analysis tools|reviewed the paper	contributed with reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
3582697	23443042	MLE	PLoS52	contributed with reagents/materials/analysis tools|reviewed the paper	reviewed the paper	Wrote the paper	Writing - Review & Editing	YES
3582697	23443042	PNS	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
3582697	23443042	PNS	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
3582697	23443042	UN	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
3582697	23443042	UN	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
3582697	23443042	UN	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
3582697	23443042	UN	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5445173	28603538	All authors	2	listed have made substantial, direct and intellectual contribution to the work, and approved it for publication	listed have made substantial, direct and intellectual contribution to the work, and approved it for publication	-	-	NO
5445173	28603538	FA	2	designed the experiment|contributed reagents, materials and analysis tools|were involved in the results interpretation and finalization of the manuscript	designed the experiment	Conceived and designed the experiments	Methodology	YES
5445173	28603538	FA	2	designed the experiment|contributed reagents, materials and analysis tools|were involved in the results interpretation and finalization of the manuscript	contributed reagents, materials and analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5445173	28603538	FA	2	designed the experiment|contributed reagents, materials and analysis tools|were involved in the results interpretation and finalization of the manuscript	were involved in the results interpretation and finalization of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5445173	28603538	KF	2	contributed to parts of the data collection and conducted the statistical analyses|drafted the manuscript	contributed to parts of the data collection and conducted the statistical analyses	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5445173	28603538	KF	2	contributed to parts of the data collection and conducted the statistical analyses|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5445173	28603538	MW	2	designed the experiment|contributed reagents, materials and analysis tools|were involved in the results interpretation and finalization of the manuscript	designed the experiment	Conceived and designed the experiments	Methodology	YES
5445173	28603538	MW	2	designed the experiment|contributed reagents, materials and analysis tools|were involved in the results interpretation and finalization of the manuscript	contributed reagents, materials and analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5445173	28603538	MW	2	designed the experiment|contributed reagents, materials and analysis tools|were involved in the results interpretation and finalization of the manuscript	were involved in the results interpretation and finalization of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5445173	28603538	PP	2	designed the experiment|contributed reagents, materials and analysis tools|were involved in the results interpretation and finalization of the manuscript	designed the experiment	Conceived and designed the experiments	Methodology	YES
5445173	28603538	PP	2	designed the experiment|contributed reagents, materials and analysis tools|were involved in the results interpretation and finalization of the manuscript	contributed reagents, materials and analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5445173	28603538	PP	2	designed the experiment|contributed reagents, materials and analysis tools|were involved in the results interpretation and finalization of the manuscript	were involved in the results interpretation and finalization of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5445173	28603538	RL	2	designed the experiment|collected the data|drafted the manuscript	designed the experiment	Conceived and designed the experiments	Methodology	YES
5445173	28603538	RL	2	designed the experiment|collected the data|drafted the manuscript	collected the data	Performed the experiments	Investigation	YES
5445173	28603538	RL	2	designed the experiment|collected the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5025617	27632983	AG	2	performed experiments and sequencing	performed experiments and sequencing	Performed the experiments	Investigation	YES
5025617	27632983	AS	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5025617	27632983	GM	2	designed the study|wrote the manuscript and all co-authors reviewed the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5025617	27632983	GM	2	designed the study|wrote the manuscript and all co-authors reviewed the manuscript	wrote the manuscript and all co-authors reviewed the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5025617	27632983	HB	2	performed experiments and sequencing	performed experiments and sequencing	Performed the experiments	Investigation	YES
5025617	27632983	NB	2	designed the study|analyzed data|wrote the manuscript and all co-authors reviewed the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5025617	27632983	NB	2	designed the study|analyzed data|wrote the manuscript and all co-authors reviewed the manuscript	analyzed data	Analyzed the data	Formal analysis	YES
5025617	27632983	NB	2	designed the study|analyzed data|wrote the manuscript and all co-authors reviewed the manuscript	wrote the manuscript and all co-authors reviewed the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5025617	27632983	RS	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5025617	27632983	SCR	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5025617	27632983	SK	2	performed experiments and sequencing	performed experiments and sequencing	Performed the experiments	Investigation	YES
5025617	27632983	VF	2	designed the study|wrote the manuscript and all co-authors reviewed the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5025617	27632983	VF	2	designed the study|wrote the manuscript and all co-authors reviewed the manuscript	wrote the manuscript and all co-authors reviewed the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4398482	25876074	AEP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398482	25876074	AEP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398482	25876074	MC	PLoS5	Wrote the paper|Critically reviewed the submission	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398482	25876074	MC	PLoS5	Wrote the paper|Critically reviewed the submission	Critically reviewed the submission	-	-	NO
4398482	25876074	MF	PLoS5	Conceived and designed the experiments|Wrote the paper|Critically reviewed the submission	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398482	25876074	MF	PLoS5	Conceived and designed the experiments|Wrote the paper|Critically reviewed the submission	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398482	25876074	MF	PLoS5	Conceived and designed the experiments|Wrote the paper|Critically reviewed the submission	Critically reviewed the submission	-	-	NO
4398482	25876074	RP	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398482	25876074	RP	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398482	25876074	SV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398482	25876074	SV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398482	25876074	SV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398482	25876074	SV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398482	25876074	SV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398482	25876074	TF	PLoS5	Conceived and designed the experiments|Wrote the paper|Critically reviewed the submission	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398482	25876074	TF	PLoS5	Conceived and designed the experiments|Wrote the paper|Critically reviewed the submission	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398482	25876074	TF	PLoS5	Conceived and designed the experiments|Wrote the paper|Critically reviewed the submission	Critically reviewed the submission	-	-	NO
4398482	25876074	TT	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6470589	30871041	A.P.	PLoS52	conceived and designed the experiments|analysed the data|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6470589	30871041	A.P.	PLoS52	conceived and designed the experiments|analysed the data|wrote the paper	analysed the data	Analyzed the data	Formal analysis	YES
6470589	30871041	A.P.	PLoS52	conceived and designed the experiments|analysed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6470589	30871041	A.S.	PLoS52	conceived and designed the experiments|contributed reagents/materials tools|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6470589	30871041	A.S.	PLoS52	conceived and designed the experiments|contributed reagents/materials tools|wrote the paper	contributed reagents/materials tools	Contributed reagents/materials/analysis tools	Resources	YES
6470589	30871041	A.S.	PLoS52	conceived and designed the experiments|contributed reagents/materials tools|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6470589	30871041	D.T.	PLoS52	analysed the data|contributed reagents/materials tools	analysed the data	Analyzed the data	Formal analysis	YES
6470589	30871041	D.T.	PLoS52	analysed the data|contributed reagents/materials tools	contributed reagents/materials tools	Contributed reagents/materials/analysis tools	Resources	YES
6470589	30871041	I.D.	PLoS52	analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
6470589	30871041	J.L.	PLoS52	performed the toxicity tests on microorganisms|analysed the data	performed the toxicity tests on microorganisms	Performed the experiments	Investigation	YES
6470589	30871041	J.L.	PLoS52	performed the toxicity tests on microorganisms|analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
6470589	30871041	K.S.	PLoS52	registered the tem images	registered the tem images	Analyzed the data	Visualization	YES
6470589	30871041	Karlis Pajuste	PLoS52	analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
6470589	30871041	Klavs Pajuste	PLoS52	performed the re-synthesis of compounds	performed the re-synthesis of compounds	Performed the experiments	Investigation	YES
6470589	30871041	M.P.	PLoS52	performed the re-synthesis of compounds|analysed the data	performed the re-synthesis of compounds	Performed the experiments	Investigation	YES
6470589	30871041	M.P.	PLoS52	performed the re-synthesis of compounds|analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
6470589	30871041	M.R.	PLoS52	performed the re-synthesis of compounds	performed the re-synthesis of compounds	Performed the experiments	Investigation	YES
6470589	30871041	P.D.	PLoS52	performed the phospholipid binding assay|analysed the data	performed the phospholipid binding assay	Performed the experiments	Investigation	YES
6470589	30871041	P.D.	PLoS52	performed the phospholipid binding assay|analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
6470589	30871041	S.K.	PLoS52	performed the toxicity tests on microorganisms	performed the toxicity tests on microorganisms	Performed the experiments	Investigation	YES
4398483	25875482	HR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398483	25875482	HR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398483	25875482	HR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398483	25875482	HR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398483	25875482	RCN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398483	25875482	RCN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398483	25875482	RCN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398483	25875482	RCN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5445174	28603532	BW	2	designed the experiments and edited the manuscript	designed the experiments and edited the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5445174	28603532	CD	2	helped in seedling planting and sample preparation	helped in seedling planting and sample preparation	Performed the experiments	Investigation	YES
5445174	28603532	MZ	2	performed most of the experiments	performed most of the experiments	Performed the experiments	Investigation	YES
5445174	28603532	PL	2	helped design the experiments and revise the manuscript	helped design the experiments and revise the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
5445174	28603532	RF	2	performed most of the experiments	performed most of the experiments	Performed the experiments	Investigation	YES
5445174	28603532	SW	2	helped in seedling planting and sample preparation	helped in seedling planting and sample preparation	Performed the experiments	Investigation	YES
5445174	28603532	XH	2	performed most of the experiments	performed most of the experiments	Performed the experiments	Investigation	YES
5445174	28603532	XS	2	helped analyze the results	helped analyze the results	Analyzed the data	Formal analysis	YES
5445174	28603532	YF	2	helped in seedling planting and sample preparation	helped in seedling planting and sample preparation	Performed the experiments	Investigation	YES
5445174	28603532	YZ	2	performed most of the experiments	performed most of the experiments	Performed the experiments	Investigation	YES
3586663	23458102	All authors	PLoS52	contributed to the writing of the final version	contributed to the writing of the final version	Wrote the paper	-	YES
3586663	23458102	D.H.	PLoS52	conceived the study|wrote the first draft of the manuscript|analyzed the data	conceived the study	Conceived and designed the experiments	Conceptualization	YES
3586663	23458102	D.H.	PLoS52	conceived the study|wrote the first draft of the manuscript|analyzed the data	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
3586663	23458102	D.H.	PLoS52	conceived the study|wrote the first draft of the manuscript|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
3586663	23458102	J.K.	PLoS52	conceived the study|wrote the first draft of the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
3586663	23458102	J.K.	PLoS52	conceived the study|wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
3586663	23458102	J.L.	PLoS52	wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
3586663	23458102	J.O.	PLoS52	collected the data and confirmed accuracy	collected the data and confirmed accuracy	Performed the experiments	Investigation	YES
3586663	23458102	J.R.	PLoS52	conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
3586663	23458102	P.C.	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
3586663	23458102	P.M.	PLoS52	collected the data and confirmed accuracy	collected the data and confirmed accuracy	Performed the experiments	Investigation	YES
4414265	25961016	Anna Krzywonos-Zawadzka	2	was responsible for experimental work	was responsible for experimental work	Performed the experiments	Investigation	YES
4414265	25961016	Dariusz Bialy	2	was responsible for hypothesis generation, experimental design, experimental work, and paper writing	was responsible for hypothesis generation, experimental design, experimental work, and paper writing	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology	YES
4414265	25961016	Grzegorz Sawicki	2	was responsible for hypothesis generation, experimental design, and paper writing	was responsible for hypothesis generation, experimental design, and paper writing	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology	YES
4414265	25961016	Iwona Bil-Lula	2	was responsible for experimental work	was responsible for experimental work	Performed the experiments	Investigation	YES
4414265	25961016	J. J. Cadete	2	was responsible for experimental design and paper writing	was responsible for experimental design and paper writing	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology	YES
4414265	25961016	Magdalena Wawrzynska	2	was responsible for experimental design, experimental work, and paper writing	was responsible for experimental design, experimental work, and paper writing	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology	YES
4414265	25961016	Mieczyslaw Wozniak	2	was responsible for experimental design and paper writing	was responsible for experimental design and paper writing	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology	YES
5847222	28643242	All authors	2	critically revised the manuscript for important intellectual content and approved the final draft	critically revised the manuscript for important intellectual content and approved the final draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5847222	28643242	DJ	2	provided technical guidance on study implementation and write up of the drph dissertation	provided technical guidance on study implementation and write up of the drph dissertation	Performed the experiments|Wrote the paper	Investigation|Supervision	YES
5847222	28643242	EJ	2	served as a second reader for the transcripts, helped determine the key themes emerging from the data, and reviewed initial write ups of the findings	served as a second reader for the transcripts, helped determine the key themes emerging from the data, and reviewed initial write ups of the findings	Wrote the paper	-	YES
5847222	28643242	FA	2	updated the literature review and drafted the manuscript using content from the drph dissertation	updated the literature review and drafted the manuscript using content from the drph dissertation	Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5847222	28643242	FF	2	provided technical guidance on study implementation and write up of the drph dissertation	provided technical guidance on study implementation and write up of the drph dissertation	Performed the experiments|Wrote the paper	Investigation|Supervision	YES
5847222	28643242	HT	2	provided technical guidance on study implementation and write up of the drph dissertation	provided technical guidance on study implementation and write up of the drph dissertation	Performed the experiments|Wrote the paper	Investigation|Supervision	YES
5847222	28643242	TD	2	provided technical guidance on study implementation and write up of the drph dissertation	provided technical guidance on study implementation and write up of the drph dissertation	Performed the experiments|Wrote the paper	Investigation|Supervision	YES
5847222	28643242	WZ	2	provided input on the interview guide, assisted with training of the interviewer, ensured quality control on the translation of transcripts, and provided technical input on the manuscript	provided input on the interview guide, assisted with training of the interviewer, ensured quality control on the translation of transcripts, and provided technical input on the manuscript	Performed the experiments	Investigation|Validation	YES
5684615	29225613	Abdalla Salama	PLoS52	conceived the idea and designed and performed the experiments presented in this manuscript|wrote the paper	conceived the idea and designed and performed the experiments presented in this manuscript	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
5684615	29225613	Abdalla Salama	PLoS52	conceived the idea and designed and performed the experiments presented in this manuscript|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5684615	29225613	Amin Malekmohammadi	PLoS52	wrote the paper|provided advice on the revisions of the manuscript and the experiment parts	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5684615	29225613	Amin Malekmohammadi	PLoS52	wrote the paper|provided advice on the revisions of the manuscript and the experiment parts	provided advice on the revisions of the manuscript and the experiment parts	Wrote the paper	Writing - Review & Editing	YES
5684615	29225613	Rajprasad Rajkumar	PLoS52	provided advice on the revisions of the manuscript and the experiment parts	provided advice on the revisions of the manuscript and the experiment parts	Wrote the paper	Writing - Review & Editing	YES
5684615	29225613	Shahram Mohanna	PLoS52	provided advice on the revisions of the manuscript and the experiment parts	provided advice on the revisions of the manuscript and the experiment parts	Wrote the paper	Writing - Review & Editing	YES
6470605	30897790	A.M.-I.	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
6470605	30897790	F.N.-P.	CRediT	Investigation|Writing--original draft	Investigation	Performed the experiments	Investigation	YES
6470605	30897790	F.N.-P.	CRediT	Investigation|Writing--original draft	Writing--original draft	Wrote the paper	Writing - Original Draft	YES
6470605	30897790	J.P.	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
6470605	30897790	M.-D.V.	CRediT	Writing--review and editing	Writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6470605	30897790	R.C.-L.	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
6470605	30897790	R.R.-C.	CRediT	Writing--review and editing	Writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
4311938	25673920	All authors	2	have given approval to the final version of the manuscript	have given approval to the final version of the manuscript	-	-	NO
5695078	29234351	Jacopo Biasetti	2	contributed equally to this work	contributed equally to this work	-	-	NO
5695078	29234351	Kaushik Sampath	2	contributed equally to this work	contributed equally to this work	-	-	NO
3386501	22754596	FK	2	helped to draft the manuscript	helped to draft the manuscript	Wrote the paper	Writing - Original Draft	YES
3386501	22754596	HK	2	helped to draft the manuscript	helped to draft the manuscript	Wrote the paper	Writing - Original Draft	YES
3386501	22754596	HN	2	performed analyses, collected data and wrote the manuscript	performed analyses, collected data and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3386501	22754596	KU	2	helped to draft the manuscript and collected data	helped to draft the manuscript and collected data	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3386501	22754596	TI	2	helped to draft the manuscript	helped to draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5445185	28603536	CE	CRediT	Conceptualization|Writing - original draft|Writing - review & editing|Funding acquisition|Resources|Supervision	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
5445185	28603536	CE	CRediT	Conceptualization|Writing - original draft|Writing - review & editing|Funding acquisition|Resources|Supervision	Writing - original draft	Wrote the paper	Writing - Original Draft	YES
5445185	28603536	CE	CRediT	Conceptualization|Writing - original draft|Writing - review & editing|Funding acquisition|Resources|Supervision	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
5445185	28603536	CE	CRediT	Conceptualization|Writing - original draft|Writing - review & editing|Funding acquisition|Resources|Supervision	Funding acquisition	-	Funding acquisition	YES
5445185	28603536	CE	CRediT	Conceptualization|Writing - original draft|Writing - review & editing|Funding acquisition|Resources|Supervision	Resources	Contributed reagents/materials/analysis tools	Resources	YES
5445185	28603536	CE	CRediT	Conceptualization|Writing - original draft|Writing - review & editing|Funding acquisition|Resources|Supervision	Supervision	-	Supervision	YES
5445185	28603536	CF	CRediT	Writing - review & editing|Funding acquisition|Resources	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
5445185	28603536	CF	CRediT	Writing - review & editing|Funding acquisition|Resources	Funding acquisition	-	Funding acquisition	YES
5445185	28603536	CF	CRediT	Writing - review & editing|Funding acquisition|Resources	Resources	Contributed reagents/materials/analysis tools	Resources	YES
5445185	28603536	HF	CRediT	Writing - review & editing	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
5445185	28603536	JC	CRediT	Conceptualization|Methodology|Investigation|Writing - original draft|Writing - review & editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
5445185	28603536	JC	CRediT	Conceptualization|Methodology|Investigation|Writing - original draft|Writing - review & editing	Methodology	Performed the experiments	Methodology	YES
5445185	28603536	JC	CRediT	Conceptualization|Methodology|Investigation|Writing - original draft|Writing - review & editing	Investigation	Performed the experiments	Investigation	YES
5445185	28603536	JC	CRediT	Conceptualization|Methodology|Investigation|Writing - original draft|Writing - review & editing	Writing - original draft	Wrote the paper	Writing - Original Draft	YES
5445185	28603536	JC	CRediT	Conceptualization|Methodology|Investigation|Writing - original draft|Writing - review & editing	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
5445185	28603536	MM-R	CRediT	Writing - review & editing	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
5445185	28603536	RO	CRediT	Conceptualization|Methodology|Investigation|Writing - original draft	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
5445185	28603536	RO	CRediT	Conceptualization|Methodology|Investigation|Writing - original draft	Methodology	Performed the experiments	Methodology	YES
5445185	28603536	RO	CRediT	Conceptualization|Methodology|Investigation|Writing - original draft	Investigation	Performed the experiments	Investigation	YES
5445185	28603536	RO	CRediT	Conceptualization|Methodology|Investigation|Writing - original draft	Writing - original draft	Wrote the paper	Writing - Original Draft	YES
4398484	25875922	CJC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398484	25875922	CJC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398484	25875922	CJC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398484	25875922	CPL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398484	25875922	CPL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398484	25875922	CPL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398484	25875922	CYL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398484	25875922	CYL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398484	25875922	CYL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398484	25875922	CYL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398484	25875922	LSW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398484	25875922	PHC	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398484	25875922	PHC	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398484	25875922	YSL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5027104	27639974	AMB	2	designed the study|secured funding	designed the study	Conceived and designed the experiments	Methodology	YES
5027104	27639974	AMB	2	designed the study|secured funding	secured funding	-	Funding acquisition	YES
5027104	27639974	AO	2	designed the study|conducted the experiment|secured funding	designed the study	Conceived and designed the experiments	Methodology	YES
5027104	27639974	AO	2	designed the study|conducted the experiment|secured funding	conducted the experiment	Performed the experiments	Investigation	YES
5027104	27639974	AO	2	designed the study|conducted the experiment|secured funding	secured funding	-	Funding acquisition	YES
5027104	27639974	PW	2	designed the study|performed the statistical analysis of microarray data	designed the study	Conceived and designed the experiments	Methodology	YES
5027104	27639974	PW	2	designed the study|performed the statistical analysis of microarray data	performed the statistical analysis of microarray data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5027104	27639974	RK	2	interpreted the microarray data and wrote the manuscript	interpreted the microarray data and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3589546	23462140	AG	PLoS5	Conceived of and designed the study|Wrote the paper	Conceived of and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3589546	23462140	AG	PLoS5	Conceived of and designed the study|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3589546	23462140	FS	PLoS5	Screened rticles and extracted data|Analysed the data|Wrote the paper	Screened rticles and extracted data	Performed the experiments	Investigation	YES
3589546	23462140	FS	PLoS5	Screened rticles and extracted data|Analysed the data|Wrote the paper	Analysed the data	Analyzed the data	Formal analysis	YES
3589546	23462140	FS	PLoS5	Screened rticles and extracted data|Analysed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3589546	23462140	IN	PLoS5	Conceived of and designed the study|Wrote the paper	Conceived of and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3589546	23462140	IN	PLoS5	Conceived of and designed the study|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3589546	23462140	MC	PLoS5	Conceived of and designed the study|Screened rticles and extracted data|Analysed the data|Wrote the paper	Conceived of and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3589546	23462140	MC	PLoS5	Conceived of and designed the study|Screened rticles and extracted data|Analysed the data|Wrote the paper	Screened rticles and extracted data	Performed the experiments	Investigation	YES
3589546	23462140	MC	PLoS5	Conceived of and designed the study|Screened rticles and extracted data|Analysed the data|Wrote the paper	Analysed the data	Analyzed the data	Formal analysis	YES
3589546	23462140	MC	PLoS5	Conceived of and designed the study|Screened rticles and extracted data|Analysed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3589546	23462140	RS	PLoS5	Conceived of and designed the study|Analysed the data|Wrote the paper	Conceived of and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3589546	23462140	RS	PLoS5	Conceived of and designed the study|Analysed the data|Wrote the paper	Analysed the data	Analyzed the data	Formal analysis	YES
3589546	23462140	RS	PLoS5	Conceived of and designed the study|Analysed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3589546	23462140	SL	PLoS5	Screened rticles and extracted data|Analysed the data|Wrote the paper	Screened rticles and extracted data	Performed the experiments	Investigation	YES
3589546	23462140	SL	PLoS5	Screened rticles and extracted data|Analysed the data|Wrote the paper	Analysed the data	Analyzed the data	Formal analysis	YES
3589546	23462140	SL	PLoS5	Screened rticles and extracted data|Analysed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3589546	23462140	YRL	PLoS5	Conceived of and designed the study|Analysed the data	Conceived of and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3589546	23462140	YRL	PLoS5	Conceived of and designed the study|Analysed the data	Analysed the data	Analyzed the data	Formal analysis	YES
6470607	30875977	A.K.	CRediT	supervision	supervision	-	Supervision	YES
6470607	30875977	I.W.	CRediT	formal analysis|investigation|data curation|writing-original draft preparation|visualization	formal analysis	Analyzed the data	Formal analysis	YES
6470607	30875977	I.W.	CRediT	formal analysis|investigation|data curation|writing-original draft preparation|visualization	investigation	Performed the experiments	Investigation	YES
6470607	30875977	I.W.	CRediT	formal analysis|investigation|data curation|writing-original draft preparation|visualization	data curation	Analyzed the data	Data curation	YES
6470607	30875977	I.W.	CRediT	formal analysis|investigation|data curation|writing-original draft preparation|visualization	writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
6470607	30875977	I.W.	CRediT	formal analysis|investigation|data curation|writing-original draft preparation|visualization	visualization	Analyzed the data	Visualization	YES
6470607	30875977	all authors	CRediT	Conceptualization|methodology|writing-review and editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6470607	30875977	all authors	CRediT	Conceptualization|methodology|writing-review and editing	methodology	Performed the experiments	Methodology	YES
6470607	30875977	all authors	CRediT	Conceptualization|methodology|writing-review and editing	writing-review and editing	Wrote the paper	Writing - Review & Editing	YES
4398485	25875356	BJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398485	25875356	BJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398485	25875356	BJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398485	25875356	GF	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398485	25875356	GF	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398485	25875356	HM	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398485	25875356	HM	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4398485	25875356	HP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398485	25875356	HP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398485	25875356	HP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398485	25875356	HP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398485	25875356	HP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398485	25875356	JC	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398485	25875356	JC	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4398485	25875356	KS	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398485	25875356	KS	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4398485	25875356	KS	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398485	25875356	PW	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398485	25875356	PW	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398485	25875356	XW	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398485	25875356	XW	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398485	25875356	YW	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398485	25875356	YW	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5445233	28603533	CT	2	was involved in gamma-ray irradiation and producing m2 seeds and initial screening of the mutant	was involved in gamma-ray irradiation and producing m2 seeds and initial screening of the mutant	Performed the experiments	Investigation	YES
5445233	28603533	HY	2	were also involved greenhouse and field evaluation of the mutant	were also involved greenhouse and field evaluation of the mutant	Performed the experiments	Investigation	YES
5445233	28603533	JI	2	provided advices on characterization of the mutant and manuscript editing	provided advices on characterization of the mutant and manuscript editing	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Resources|Writing - Review & Editing	YES
5445233	28603533	JW	2	provided advices on transcriptome data analysis and manuscript editing	provided advices on transcriptome data analysis and manuscript editing	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
5445233	28603533	KG	2	provided advices on characterization of the mutant and manuscript editing	provided advices on characterization of the mutant and manuscript editing	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Resources|Writing - Review & Editing	YES
5445233	28603533	LK-G	2	are equally contributed and did most of the work for mutant characterization|were responsible for analysis of degs|were involved in manuscript writing and editing	are equally contributed and did most of the work for mutant characterization	Performed the experiments	Investigation	YES
5445233	28603533	LK-G	2	are equally contributed and did most of the work for mutant characterization|were responsible for analysis of degs|were involved in manuscript writing and editing	were responsible for analysis of degs	-	-	NO
5445233	28603533	LK-G	2	are equally contributed and did most of the work for mutant characterization|were responsible for analysis of degs|were involved in manuscript writing and editing	were involved in manuscript writing and editing	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5445233	28603533	RE-T	2	were responsible for analysis of degs|were also involved greenhouse and field evaluation of the mutant	were responsible for analysis of degs	-	-	NO
5445233	28603533	RE-T	2	were responsible for analysis of degs|were also involved greenhouse and field evaluation of the mutant	were also involved greenhouse and field evaluation of the mutant	Performed the experiments	Investigation	YES
5445233	28603533	RM	2	provided advices on characterization of the mutant and manuscript editing	provided advices on characterization of the mutant and manuscript editing	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Resources|Writing - Review & Editing	YES
5445233	28603533	TG	2	designed experiments for the mutant characterization and transcriptome analysis	designed experiments for the mutant characterization and transcriptome analysis	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5445233	28603533	WL	2	are equally contributed and did most of the work for mutant characterization|were responsible for analysis of degs|were involved in manuscript writing and editing	are equally contributed and did most of the work for mutant characterization	Performed the experiments	Investigation	YES
5445233	28603533	WL	2	are equally contributed and did most of the work for mutant characterization|were responsible for analysis of degs|were involved in manuscript writing and editing	were responsible for analysis of degs	-	-	NO
5445233	28603533	WL	2	are equally contributed and did most of the work for mutant characterization|were responsible for analysis of degs|were involved in manuscript writing and editing	were involved in manuscript writing and editing	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5445233	28603533	XG	2	were responsible for mapping of transcriptome data|were responsible for analysis of degs	were responsible for mapping of transcriptome data	-	-	NO
5445233	28603533	XG	2	were responsible for mapping of transcriptome data|were responsible for analysis of degs	were responsible for analysis of degs	-	-	NO
5445233	28603533	XW	2	were responsible for mapping of transcriptome data|were responsible for analysis of degs	were responsible for mapping of transcriptome data	-	-	NO
5445233	28603533	XW	2	were responsible for mapping of transcriptome data|were responsible for analysis of degs	were responsible for analysis of degs	-	-	NO
5445233	28603533	YL	2	designed experiments for the mutant characterization and transcriptome analysis|were involved in manuscript writing and editing	designed experiments for the mutant characterization and transcriptome analysis	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5445233	28603533	YL	2	designed experiments for the mutant characterization and transcriptome analysis|were involved in manuscript writing and editing	were involved in manuscript writing and editing	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5027110	27640124	GAR	2	contributed to the writing of the manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5027110	27640124	KH	2	conceived of the study and designed the experiments|performed the experiments and analyzed the data|contributed to the writing of the manuscript	conceived of the study and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5027110	27640124	KH	2	conceived of the study and designed the experiments|performed the experiments and analyzed the data|contributed to the writing of the manuscript	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5027110	27640124	KH	2	conceived of the study and designed the experiments|performed the experiments and analyzed the data|contributed to the writing of the manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5027110	27640124	MS	2	conceived of the study and designed the experiments|performed the experiments and analyzed the data|contributed to the writing of the manuscript	conceived of the study and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5027110	27640124	MS	2	conceived of the study and designed the experiments|performed the experiments and analyzed the data|contributed to the writing of the manuscript	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5027110	27640124	MS	2	conceived of the study and designed the experiments|performed the experiments and analyzed the data|contributed to the writing of the manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5027110	27640124	SKH	2	contributed to the writing of the manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5027110	27640124	WS	2	conceived of the study and designed the experiments|contributed to the writing of the manuscript	conceived of the study and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5027110	27640124	WS	2	conceived of the study and designed the experiments|contributed to the writing of the manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
3593140	23473096	MAW	2	critically read and revised subsequent versions	critically read and revised subsequent versions	Wrote the paper	Writing - Review & Editing	YES
3593140	23473096	PSS	2	critically read and revised subsequent versions	critically read and revised subsequent versions	Wrote the paper	Writing - Review & Editing	YES
3593140	23473096	SH	2	wrote the first draft	wrote the first draft	Wrote the paper	Writing - Original Draft	YES
3593140	23473096	SK	2	critically read and revised subsequent versions	critically read and revised subsequent versions	Wrote the paper	Writing - Review & Editing	YES
5878835	28699018	All authors	2	critically reviewed the manuscript	critically reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5878835	28699018	ITE	2	developed the research questions for this study|conducted the statistical analyses, interpreted results and wrote the manuscript	developed the research questions for this study	Conceived and designed the experiments	Conceptualization	YES
5878835	28699018	ITE	2	developed the research questions for this study|conducted the statistical analyses, interpreted results and wrote the manuscript	conducted the statistical analyses, interpreted results and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5878835	28699018	MCB	2	developed the research questions for this study	developed the research questions for this study	Conceived and designed the experiments	Conceptualization	YES
5878835	28699018	MMG	2	conducted the statistical analyses, interpreted results and wrote the manuscript	conducted the statistical analyses, interpreted results and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4398486	25876075	CRW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398486	25876075	CRW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398486	25876075	CRW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398486	25876075	CRW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398486	25876075	EK	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4398486	25876075	EK	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4398486	25876075	JM	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4398486	25876075	JS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4398486	25876075	JS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4398486	25876075	MCFC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398486	25876075	MCFC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398486	25876075	MCFC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398486	25876075	MCFC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398486	25876075	NHP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398486	25876075	NHP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4398486	25876075	NHP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5445427	28603534	HY	2	performed experiments with metabolic profiling analyses and gene expression analyses	performed experiments with metabolic profiling analyses and gene expression analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5445427	28603534	L-wQ	2	designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
5445427	28603534	NW	2	wrote and revised the article	wrote and revised the article	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5445427	28603534	PL	2	designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
5445427	28603534	QS	2	wrote and revised the article	wrote and revised the article	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5445427	28603534	XGL	2	performed experiments with metabolic profiling analyses and gene expression analyses	performed experiments with metabolic profiling analyses and gene expression analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5445427	28603534	XL	2	designed the research|performed experiments with metabolic profiling analyses and gene expression analyses|wrote and revised the article	designed the research	Conceived and designed the experiments	Methodology	YES
5445427	28603534	XL	2	designed the research|performed experiments with metabolic profiling analyses and gene expression analyses|wrote and revised the article	performed experiments with metabolic profiling analyses and gene expression analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5445427	28603534	XL	2	designed the research|performed experiments with metabolic profiling analyses and gene expression analyses|wrote and revised the article	wrote and revised the article	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3595419	23481130	BT	2	contributed to the design of the study, collected and analyzed data and wrote the first draft of the manuscript	contributed to the design of the study, collected and analyzed data and wrote the first draft of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
3595419	23481130	HK	2	coordinated the study and critically reviewed the manuscript	coordinated the study and critically reviewed the manuscript	Wrote the paper	Project administration|Writing - Review & Editing	YES
3595419	23481130	JS	2	coordinated the study and critically reviewed the manuscript	coordinated the study and critically reviewed the manuscript	Wrote the paper	Project administration|Writing - Review & Editing	YES
3595419	23481130	MHOR	2	participated in the designing of the study, analysis of data and revising of the manuscript	participated in the designing of the study, analysis of data and revising of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
5027121	27640184	AL	2	carried out experiments in diploid cells	carried out experiments in diploid cells	Performed the experiments	Investigation	YES
5027121	27640184	SA	2	carried out experiments in diploid cells	carried out experiments in diploid cells	Performed the experiments	Investigation	YES
5027121	27640184	SL	2	designed the study, interpreted data, and wrote the manuscript|carried out all experiments, except the ones in diploid cells	designed the study, interpreted data, and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5027121	27640184	SL	2	designed the study, interpreted data, and wrote the manuscript|carried out all experiments, except the ones in diploid cells	carried out all experiments, except the ones in diploid cells	Performed the experiments	Investigation	YES
5027121	27640184	TB	2	designed the study, interpreted data, and wrote the manuscript	designed the study, interpreted data, and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
6470662	30813634	C.J.	CRediT	resources	resources	Contributed reagents/materials/analysis tools	Resources	YES
6470662	30813634	K.L.	CRediT	Conceptualization|writing--original draft preparation|writing--review and editing|data curation|visualization|project administration	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6470662	30813634	K.L.	CRediT	Conceptualization|writing--original draft preparation|writing--review and editing|data curation|visualization|project administration	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6470662	30813634	K.L.	CRediT	Conceptualization|writing--original draft preparation|writing--review and editing|data curation|visualization|project administration	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6470662	30813634	K.L.	CRediT	Conceptualization|writing--original draft preparation|writing--review and editing|data curation|visualization|project administration	data curation	Analyzed the data	Data curation	YES
6470662	30813634	K.L.	CRediT	Conceptualization|writing--original draft preparation|writing--review and editing|data curation|visualization|project administration	visualization	Analyzed the data	Visualization	YES
6470662	30813634	K.L.	CRediT	Conceptualization|writing--original draft preparation|writing--review and editing|data curation|visualization|project administration	project administration	-	Project administration	YES
6470662	30813634	S.H.P.	CRediT	writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6470662	30813634	W.R.	CRediT	Conceptualization|resources|writing--review and editing|supervision|project administration|funding acquisition	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6470662	30813634	W.R.	CRediT	Conceptualization|resources|writing--review and editing|supervision|project administration|funding acquisition	resources	Contributed reagents/materials/analysis tools	Resources	YES
6470662	30813634	W.R.	CRediT	Conceptualization|resources|writing--review and editing|supervision|project administration|funding acquisition	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6470662	30813634	W.R.	CRediT	Conceptualization|resources|writing--review and editing|supervision|project administration|funding acquisition	supervision	-	Supervision	YES
6470662	30813634	W.R.	CRediT	Conceptualization|resources|writing--review and editing|supervision|project administration|funding acquisition	project administration	-	Project administration	YES
6470662	30813634	W.R.	CRediT	Conceptualization|resources|writing--review and editing|supervision|project administration|funding acquisition	funding acquisition	-	Funding acquisition	YES
5445667	28603528	BA	2	analyzed and discussed the results	analyzed and discussed the results	Analyzed the data	Formal analysis	YES
5445667	28603528	CL	2	performed the experiments with|analyzed and discussed the results|wrote the manuscript	performed the experiments with	Performed the experiments	Investigation	YES
5445667	28603528	CL	2	performed the experiments with|analyzed and discussed the results|wrote the manuscript	analyzed and discussed the results	Analyzed the data	Formal analysis	YES
5445667	28603528	CL	2	performed the experiments with|analyzed and discussed the results|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5445667	28603528	HL	2	assisted with the performed the experiments with	assisted with the performed the experiments with	Performed the experiments	Investigation	YES
5445667	28603528	WZ	2	designed the experiments|analyzed and discussed the results|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5445667	28603528	WZ	2	designed the experiments|analyzed and discussed the results|wrote the manuscript	analyzed and discussed the results	Analyzed the data	Formal analysis	YES
5445667	28603528	WZ	2	designed the experiments|analyzed and discussed the results|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5445667	28603528	XW	2	performed the experiments with|analyzed and discussed the results|wrote the manuscript	performed the experiments with	Performed the experiments	Investigation	YES
5445667	28603528	XW	2	performed the experiments with|analyzed and discussed the results|wrote the manuscript	analyzed and discussed the results	Analyzed the data	Formal analysis	YES
5445667	28603528	XW	2	performed the experiments with|analyzed and discussed the results|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5445667	28603528	ZQ	2	performed the experiments with|analyzed and discussed the results|wrote the manuscript	performed the experiments with	Performed the experiments	Investigation	YES
5445667	28603528	ZQ	2	performed the experiments with|analyzed and discussed the results|wrote the manuscript	analyzed and discussed the results	Analyzed the data	Formal analysis	YES
5445667	28603528	ZQ	2	performed the experiments with|analyzed and discussed the results|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4398487	25875813	EB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398487	25875813	EB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4398487	25875813	EB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4398487	25875813	EB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398487	25875813	GS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398487	25875813	GS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398487	25875813	GS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398487	25875813	GS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398487	25875813	GS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398487	25875813	GV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398487	25875813	GV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398487	25875813	GV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398487	25875813	GV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398487	25875813	GV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398487	25875813	HS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398487	25875813	HS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4398487	25875813	HS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4398487	25875813	MK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398487	25875813	MK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398487	25875813	MK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398487	25875813	MK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398487	25875813	PH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398487	25875813	PH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398487	25875813	PH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398487	25875813	PH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398487	25875813	PH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398487	25875813	RZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398487	25875813	RZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4398487	25875813	RZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4398487	25875813	RZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398487	25875813	S. Klein	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398487	25875813	S. Klein	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4398487	25875813	S. Klein	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4398487	25875813	S. Klein	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398487	25875813	S. Korkmaz	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398487	25875813	S. Korkmaz	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398487	25875813	S. Korkmaz	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398487	25875813	S. Korkmaz	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398487	25875813	S. Korkmaz	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398487	25875813	TR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398487	25875813	TR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398487	25875813	TR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398487	25875813	TR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398487	25875813	TR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3604364	23517716	ADP	2	was lead researcher, designing and coordinating all aspects of the data collection and analysis as well as writing the first draft of the article	was lead researcher, designing and coordinating all aspects of the data collection and analysis as well as writing the first draft of the article	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Project administration|Writing - Original Draft	YES
3604364	23517716	AKC	2	provided input and support throughout the design, collection and analysis of the data, and reviewed the transcript providing helpful comments	provided input and support throughout the design, collection and analysis of the data, and reviewed the transcript providing helpful comments	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
3604364	23517716	BR	2	helped conduct data collection and analysis and provided an extensive review of the manuscript	helped conduct data collection and analysis and provided an extensive review of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
3604364	23517716	DC	2	programme in zomba district	programme in zomba district	-	-	NO
3604364	23517716	MvL	2	provided extensive support during the design of the study as well as during the data collection and analysis and also providing an extensive review of the final manuscript	provided extensive support during the design of the study as well as during the data collection and analysis and also providing an extensive review of the final manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Review & Editing	YES
3604364	23517716	SS	2	provided input and support throughout the design, collection and analysis of the data, and reviewed the transcript providing helpful comments	provided input and support throughout the design, collection and analysis of the data, and reviewed the transcript providing helpful comments	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
3354720	22629212	Both authors	2	equally contributed to this work	equally contributed to this work	-	-	NO
5029015	27645563	BYC	PLoS52	contributed reagents/materials/analysis tools	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5029015	27645563	DDD	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5029015	27645563	DDD	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5029015	27645563	DDD	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5029015	27645563	DDD	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5029015	27645563	FY	PLoS52	contributed reagents/materials/analysis tools	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5029015	27645563	HJ	PLoS52	contributed reagents/materials/analysis tools	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5029015	27645563	JLK	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5029015	27645563	LLT	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5029015	27645563	LX	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5029015	27645563	NB	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5029015	27645563	QZ	PLoS52	contributed reagents/materials/analysis tools	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5029015	27645563	WXF	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5029015	27645563	XM	PLoS52	conceived and designed the experiments|wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5029015	27645563	XM	PLoS52	conceived and designed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5029015	27645563	XPY	PLoS52	contributed reagents/materials/analysis tools	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5029015	27645563	YY	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5029015	27645563	YYH	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
4398488	25875949	BW	PLoS5	Analyzed the data|Responsible for data collection	Analyzed the data	Analyzed the data	Formal analysis	YES
4398488	25875949	BW	PLoS5	Analyzed the data|Responsible for data collection	Responsible for data collection	Performed the experiments	Investigation	YES
4398488	25875949	CV	PLoS5	Analyzed the data|Responsible for data collection	Analyzed the data	Analyzed the data	Formal analysis	YES
4398488	25875949	CV	PLoS5	Analyzed the data|Responsible for data collection	Responsible for data collection	Performed the experiments	Investigation	YES
4398488	25875949	HM	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398488	25875949	HM	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398488	25875949	JFB	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398488	25875949	JFB	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398488	25875949	RW	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398488	25875949	RW	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398488	25875949	SM	PLoS5	Analyzed the data|Responsible for data collection	Analyzed the data	Analyzed the data	Formal analysis	YES
4398488	25875949	SM	PLoS5	Analyzed the data|Responsible for data collection	Responsible for data collection	Performed the experiments	Investigation	YES
5446985	28611808	HL	2	designed the study, performed the analyses and drafted the manuscript	designed the study, performed the analyses and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5446985	28611808	YZ	2	initiated, designed and supervised the study, and revised the manuscript	initiated, designed and supervised the study, and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Supervision|Writing - Review & Editing	YES
5446985	28611808	ZZ	2	initiated, designed and supervised the study, and revised the manuscript	initiated, designed and supervised the study, and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Supervision|Writing - Review & Editing	YES
3605405	23517715	All authors	PLoS52	participated in the design of the study|participated in the drafting and approval of the manuscript	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
3605405	23517715	All authors	PLoS52	participated in the design of the study|participated in the drafting and approval of the manuscript	participated in the drafting and approval of the manuscript	Wrote the paper	Writing - Original Draft	YES
3605405	23517715	LO	PLoS52	participated in the data collection and follow-up|analyzed the data	participated in the data collection and follow-up	Performed the experiments	Investigation	YES
3605405	23517715	LO	PLoS52	participated in the data collection and follow-up|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
3605405	23517715	YB	PLoS52	participated in the data collection and follow-up	participated in the data collection and follow-up	Performed the experiments	Investigation	YES
5029033	27650568	RMR	PLoS52	performed the study|analysed the data|wrote the first draft of the manuscript	performed the study	Performed the experiments	Investigation	YES
5029033	27650568	RMR	PLoS52	performed the study|analysed the data|wrote the first draft of the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
5029033	27650568	RMR	PLoS52	performed the study|analysed the data|wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
5029033	27650568	RS	PLoS52	conceived and designed the study|analysed the data|revised the final version of the text	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5029033	27650568	RS	PLoS52	conceived and designed the study|analysed the data|revised the final version of the text	analysed the data	Analyzed the data	Formal analysis	YES
5029033	27650568	RS	PLoS52	conceived and designed the study|analysed the data|revised the final version of the text	revised the final version of the text	Wrote the paper	Writing - Review & Editing	YES
5029033	27650568	SNP	PLoS52	performed the study|analysed the data	performed the study	Performed the experiments	Investigation	YES
5029033	27650568	SNP	PLoS52	performed the study|analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
3608854	23531276	AV	2	contributed to the interpretation of data and made critical revisions	contributed to the interpretation of data and made critical revisions	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
3608854	23531276	CM	2	drafted and revised the manuscript	drafted and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3608854	23531276	JV	2	contributed to the conception and design and made critical revisions	contributed to the conception and design and made critical revisions	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
3608854	23531276	MS	2	contributed critical revisions to the manuscript for intellectual content	contributed critical revisions to the manuscript for intellectual content	Wrote the paper	Writing - Review & Editing	YES
3608854	23531276	PR	2	contributed to the conception and design and made critical revisions	contributed to the conception and design and made critical revisions	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
3608854	23531276	PV	2	contributed to the conception and design and made critical revisions	contributed to the conception and design and made critical revisions	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
4398489	25875852	AR	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398489	25875852	AR	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398489	25875852	CK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398489	25875852	CK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398489	25875852	CK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398489	25875852	EA	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398489	25875852	HMH	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398489	25875852	KS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398489	25875852	PW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398489	25875852	PW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398489	25875852	PW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398489	25875852	PW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398489	25875852	RW	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398489	25875852	RW	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6470752	30845761	C.S.	CRediT	methodology	methodology	Performed the experiments	Methodology	YES
6470752	30845761	H.Z.	CRediT	methodology|data curation|writing--original draft preparation	methodology	Performed the experiments	Methodology	YES
6470752	30845761	H.Z.	CRediT	methodology|data curation|writing--original draft preparation	data curation	Analyzed the data	Data curation	YES
6470752	30845761	H.Z.	CRediT	methodology|data curation|writing--original draft preparation	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6470752	30845761	J.C.	CRediT	data curation	data curation	Analyzed the data	Data curation	YES
6470752	30845761	J.Y.	CRediT	Conceptualization|writing--review and editing|supervision	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6470752	30845761	J.Y.	CRediT	Conceptualization|writing--review and editing|supervision	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6470752	30845761	J.Y.	CRediT	Conceptualization|writing--review and editing|supervision	supervision	-	Supervision	YES
6470752	30845761	M.A.-F.	CRediT	writing--original draft preparation	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6470752	30845761	Qilong Wang	CRediT	methodology	methodology	Performed the experiments	Methodology	YES
6470752	30845761	W.D.	CRediT	writing--original draft preparation	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6470752	30845761	X.X.	CRediT	Conceptualization|writing--review and editing|supervision	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6470752	30845761	X.X.	CRediT	Conceptualization|writing--review and editing|supervision	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6470752	30845761	X.X.	CRediT	Conceptualization|writing--review and editing|supervision	supervision	-	Supervision	YES
6470752	30845761	Y.Z.	CRediT	data curation	data curation	Analyzed the data	Data curation	YES
5446987	28611796	HL	PLoS52	performed the experiment	performed the experiment	Performed the experiments	Investigation	YES
5446987	28611796	JL	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5446987	28611796	QC	PLoS52	designed the experiment|performed the experiment	designed the experiment	Conceived and designed the experiments	Methodology	YES
5446987	28611796	QC	PLoS52	designed the experiment|performed the experiment	performed the experiment	Performed the experiments	Investigation	YES
5446987	28611796	YC	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5446987	28611796	YM	PLoS52	designed the experiment|performed the experiment|analyzed the data|wrote the paper	designed the experiment	Conceived and designed the experiments	Methodology	YES
5446987	28611796	YM	PLoS52	designed the experiment|performed the experiment|analyzed the data|wrote the paper	performed the experiment	Performed the experiments	Investigation	YES
5446987	28611796	YM	PLoS52	designed the experiment|performed the experiment|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5446987	28611796	YM	PLoS52	designed the experiment|performed the experiment|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5446987	28611796	ZC	PLoS52	designed the experiment|wrote the paper	designed the experiment	Conceived and designed the experiments	Methodology	YES
5446987	28611796	ZC	PLoS52	designed the experiment|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5902521	28194585	AT	2	acquired the data	acquired the data	Performed the experiments	Investigation	YES
5902521	28194585	All authors	2	reviewed and contributed to the final manuscript	reviewed and contributed to the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5902521	28194585	CN	2	were involved in the study concept and design|acquired the data	were involved in the study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5902521	28194585	CN	2	were involved in the study concept and design|acquired the data	acquired the data	Performed the experiments	Investigation	YES
5902521	28194585	JE	2	supervised the analysis and assisted with interpretation of the results	supervised the analysis and assisted with interpretation of the results	Analyzed the data	Formal analysis|Supervision	YES
5902521	28194585	LS	2	were involved in the study concept and design	were involved in the study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5902521	28194585	MT	2	did the statistical analysis|drafted the article	did the statistical analysis	Analyzed the data	Formal analysis	YES
5902521	28194585	MT	2	did the statistical analysis|drafted the article	drafted the article	Wrote the paper	Writing - Original Draft	YES
5902521	28194585	NS	2	were involved in the study concept and design	were involved in the study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5902521	28194585	RM	2	acquired the data	acquired the data	Performed the experiments	Investigation	YES
5902521	28194585	RR	2	supervised the analysis and assisted with interpretation of the results	supervised the analysis and assisted with interpretation of the results	Analyzed the data	Formal analysis|Supervision	YES
5902521	28194585	SG	2	were involved in the study concept and design|supervised the analysis and assisted with interpretation of the results|drafted the article	were involved in the study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5902521	28194585	SG	2	were involved in the study concept and design|supervised the analysis and assisted with interpretation of the results|drafted the article	supervised the analysis and assisted with interpretation of the results	Analyzed the data	Formal analysis|Supervision	YES
5902521	28194585	SG	2	were involved in the study concept and design|supervised the analysis and assisted with interpretation of the results|drafted the article	drafted the article	Wrote the paper	Writing - Original Draft	YES
5446989	28611798	EK	2	planned and conducted the analyses, and wrote the paper	planned and conducted the analyses, and wrote the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
5446989	28611798	WL	2	conducted preliminary analyses and participated in early planning discussions	conducted preliminary analyses and participated in early planning discussions	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
3612273	23541090	DA	2	participated in the study design and helped draft the manuscript	participated in the study design and helped draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3612273	23541090	MHD	2	conceived of the study, participated in its design, coordinated the collection and analysis of data and helped draft the manuscript	conceived of the study, participated in its design, coordinated the collection and analysis of data and helped draft the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Project administration|Writing - Original Draft	YES
4398490	25875093	AH	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398490	25875093	AT	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398490	25875093	ED	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398490	25875093	MGS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398490	25875093	MR	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398490	25875093	MR	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398490	25875093	PAF	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398490	25875093	RK	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398490	25875093	SG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398490	25875093	SG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398490	25875093	SG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398490	25875093	SG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398490	25875093	SS	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4398490	25875093	TA	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398490	25875093	WA	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4398490	25875093	YE	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5031250	27654331	AL	2	carried out all laboratory work including sample collection	carried out all laboratory work including sample collection	Performed the experiments	Investigation	YES
5031250	27654331	AM	2	designed, initiated and supervised the project	designed, initiated and supervised the project	Conceived and designed the experiments	Conceptualization|Methodology|Supervision	YES
5031250	27654331	All authors	2	agreed with the final draft of the manuscript	agreed with the final draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
5031250	27654331	FM	2	designed, initiated and supervised the project	designed, initiated and supervised the project	Conceived and designed the experiments	Conceptualization|Methodology|Supervision	YES
5031250	27654331	GD	2	performed the bioinformatics analysis at different stages of the project	performed the bioinformatics analysis at different stages of the project	Performed the experiments	Formal analysis|Investigation	YES
5031250	27654331	MR	2	prepared the manuscript for publication|performed the bioinformatics analysis at different stages of the project	prepared the manuscript for publication	Wrote the paper	Writing - Original Draft	YES
5031250	27654331	MR	2	prepared the manuscript for publication|performed the bioinformatics analysis at different stages of the project	performed the bioinformatics analysis at different stages of the project	Performed the experiments	Formal analysis|Investigation	YES
5031250	27654331	PM	2	performed the bioinformatics analysis at different stages of the project	performed the bioinformatics analysis at different stages of the project	Performed the experiments	Formal analysis|Investigation	YES
5031250	27654331	RNA	2	purification and gene quantification	purification and gene quantification	Performed the experiments	Investigation	YES
5031250	27654331	SP	2	performed the bioinformatics analysis at different stages of the project	performed the bioinformatics analysis at different stages of the project	Performed the experiments	Formal analysis|Investigation	YES
5031250	27654331	TS	2	designed, initiated and supervised the project|prepared the manuscript for publication	designed, initiated and supervised the project	Conceived and designed the experiments	Conceptualization|Methodology|Supervision	YES
5031250	27654331	TS	2	designed, initiated and supervised the project|prepared the manuscript for publication	prepared the manuscript for publication	Wrote the paper	Writing - Original Draft	YES
4398491	25874997	DC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398491	25874997	DC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398491	25874997	DC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398491	25874997	DC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398491	25874997	DMB	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398491	25874997	DMB	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398491	25874997	SRC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398491	25874997	SRC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398491	25874997	SRC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398491	25874997	SRC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3615176	23547778	DMM	2	participated in the design and management of study implementation, reviewed and edited the manuscript	participated in the design and management of study implementation, reviewed and edited the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Project administration|Writing - Review & Editing	YES
3615176	23547778	JC	2	implemented study procedures, reviewed and edited the manuscript	implemented study procedures, reviewed and edited the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
3615176	23547778	JM	2	participated in the design and management of study implementation, reviewed and edited the manuscript	participated in the design and management of study implementation, reviewed and edited the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Project administration|Writing - Review & Editing	YES
3615176	23547778	JPE	2	analyzed the data and wrote the paper	analyzed the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3615176	23547778	SM	2	reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
3615176	23547778	WW	2	implemented study procedures, reviewed and edited the manuscript	implemented study procedures, reviewed and edited the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5446994	28611802	CU	2	interpreted the data and revised the manuscript	interpreted the data and revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5446994	28611802	EV	2	performed the experimental design, laboratory experiments, bioinformatics analysis, and drafted the manuscript	performed the experimental design, laboratory experiments, bioinformatics analysis, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5446994	28611802	RC	2	interpreted the data and revised the manuscript	interpreted the data and revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5446994	28611802	RS	2	designed the project, supervised the research study, interpreted the data, and drafted and revised the manuscript	designed the project, supervised the research study, interpreted the data, and drafted and revised the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
5446994	28611802	SG	2	designed the project, supervised the research study, interpreted the data, and drafted and revised the manuscript	designed the project, supervised the research study, interpreted the data, and drafted and revised the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
6097720	29464430	AT	PLoS5	Conceived the study|Developed the search strategy|Conducted online database searches and screened data|Extracted and analyzed the data|Wrote the paper|Approved the final version of the manuscript	Conceived the study	Conceived and designed the experiments	Conceptualization	YES
6097720	29464430	AT	PLoS5	Conceived the study|Developed the search strategy|Conducted online database searches and screened data|Extracted and analyzed the data|Wrote the paper|Approved the final version of the manuscript	Developed the search strategy	-	-	NO
6097720	29464430	AT	PLoS5	Conceived the study|Developed the search strategy|Conducted online database searches and screened data|Extracted and analyzed the data|Wrote the paper|Approved the final version of the manuscript	Conducted online database searches and screened data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
6097720	29464430	AT	PLoS5	Conceived the study|Developed the search strategy|Conducted online database searches and screened data|Extracted and analyzed the data|Wrote the paper|Approved the final version of the manuscript	Extracted and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6097720	29464430	AT	PLoS5	Conceived the study|Developed the search strategy|Conducted online database searches and screened data|Extracted and analyzed the data|Wrote the paper|Approved the final version of the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6097720	29464430	AT	PLoS5	Conceived the study|Developed the search strategy|Conducted online database searches and screened data|Extracted and analyzed the data|Wrote the paper|Approved the final version of the manuscript	Approved the final version of the manuscript	-	-	NO
6097720	29464430	JB	PLoS5	Provided critical comments on the manuscript|Approved the final version of the manuscript	Provided critical comments on the manuscript	-	-	NO
6097720	29464430	JB	PLoS5	Provided critical comments on the manuscript|Approved the final version of the manuscript	Approved the final version of the manuscript	-	-	NO
6097720	29464430	JEB	PLoS5	Provided critical comments on the manuscript|Approved the final version of the manuscript	Provided critical comments on the manuscript	-	-	NO
6097720	29464430	JEB	PLoS5	Provided critical comments on the manuscript|Approved the final version of the manuscript	Approved the final version of the manuscript	-	-	NO
6097720	29464430	MR	PLoS5	Conceived the study|Developed the search strategy|Contributed to writing the paper|Provided critical comments on the manuscript|Approved the final version of the manuscript	Conceived the study	Conceived and designed the experiments	Conceptualization	YES
6097720	29464430	MR	PLoS5	Conceived the study|Developed the search strategy|Contributed to writing the paper|Provided critical comments on the manuscript|Approved the final version of the manuscript	Developed the search strategy	-	-	NO
6097720	29464430	MR	PLoS5	Conceived the study|Developed the search strategy|Contributed to writing the paper|Provided critical comments on the manuscript|Approved the final version of the manuscript	Contributed to writing the paper	Wrote the paper	Writing - Original Draft	YES
6097720	29464430	MR	PLoS5	Conceived the study|Developed the search strategy|Contributed to writing the paper|Provided critical comments on the manuscript|Approved the final version of the manuscript	Provided critical comments on the manuscript	-	-	NO
6097720	29464430	MR	PLoS5	Conceived the study|Developed the search strategy|Contributed to writing the paper|Provided critical comments on the manuscript|Approved the final version of the manuscript	Approved the final version of the manuscript	-	-	NO
5484333	27739138	AE	2	contributed to the design of the study and edited the manuscript for important intellectual content	contributed to the design of the study and edited the manuscript for important intellectual content	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5484333	27739138	GO	2	contributed to the design of the study and edited the manuscript for important intellectual content|contributed to the data analysis	contributed to the design of the study and edited the manuscript for important intellectual content	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5484333	27739138	GO	2	contributed to the design of the study and edited the manuscript for important intellectual content|contributed to the data analysis	contributed to the data analysis	Analyzed the data	Formal analysis	YES
5484333	27739138	PW	2	was responsible for conceiving and designing the study, collecting and analysing the data, and writing the manuscript	was responsible for conceiving and designing the study, collecting and analysing the data, and writing the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5031335	27654840	KK	2	provided valuable advises in developing the proposed procedure from the point of view of statistics and bioinformatics	provided valuable advises in developing the proposed procedure from the point of view of statistics and bioinformatics	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation	YES
5031335	27654840	KM	2	assisted in constructing experimental design, collecting data and preparing the manuscript	assisted in constructing experimental design, collecting data and preparing the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5031335	27654840	MN	2	supervised the whole project	supervised the whole project	-	Supervision	YES
5031335	27654840	TH	2	conceived and designed the study, and wrote the manuscript	conceived and designed the study, and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
5031335	27654840	TM	2	assisted in constructing experimental design, collecting data and preparing the manuscript	assisted in constructing experimental design, collecting data and preparing the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5031335	27654840	YK	2	provided valuable advises in developing the proposed procedure from the point of view of statistics and bioinformatics	provided valuable advises in developing the proposed procedure from the point of view of statistics and bioinformatics	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation	YES
4398492	25874948	CP	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398492	25874948	CP	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398492	25874948	FB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398492	25874948	FKT	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4398492	25874948	FKT	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4398492	25874948	FKT	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398492	25874948	J. Plant	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398492	25874948	J. Poitras	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398492	25874948	JGM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398492	25874948	JM	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398492	25874948	JM	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398492	25874948	JMG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398492	25874948	LDA	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398492	25874948	PA	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398492	25874948	RF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398492	25874948	RF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398492	25874948	RF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398492	25874948	RF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6470807	30893859	A.A.	CRediT	investigation	investigation	Performed the experiments	Investigation	YES
6470807	30893859	J.K.-K.	CRediT	investigation|writing--original draft preparation|visualization	investigation	Performed the experiments	Investigation	YES
6470807	30893859	J.K.-K.	CRediT	investigation|writing--original draft preparation|visualization	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6470807	30893859	J.K.-K.	CRediT	investigation|writing--original draft preparation|visualization	visualization	Analyzed the data	Visualization	YES
6470807	30893859	J.O.	CRediT	investigation	investigation	Performed the experiments	Investigation	YES
6470807	30893859	J.S.	CRediT	Conceptualization|investigation|writing--original draft preparation|visualization	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6470807	30893859	J.S.	CRediT	Conceptualization|investigation|writing--original draft preparation|visualization	investigation	Performed the experiments	Investigation	YES
6470807	30893859	J.S.	CRediT	Conceptualization|investigation|writing--original draft preparation|visualization	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6470807	30893859	J.S.	CRediT	Conceptualization|investigation|writing--original draft preparation|visualization	visualization	Analyzed the data	Visualization	YES
6470807	30893859	K.C.	CRediT	investigation	investigation	Performed the experiments	Investigation	YES
6470807	30893859	K.G.	CRediT	investigation	investigation	Performed the experiments	Investigation	YES
6470807	30893859	M.K.	CRediT	investigation	investigation	Performed the experiments	Investigation	YES
6470807	30893859	M.P.	CRediT	writing--review and editing|supervision	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6470807	30893859	M.P.	CRediT	writing--review and editing|supervision	supervision	-	Supervision	YES
6470807	30893859	R.J.	CRediT	writing--review and editing|supervision	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6470807	30893859	R.J.	CRediT	writing--review and editing|supervision	supervision	-	Supervision	YES
3619032	23561044	All authors	2	contributed to the development of the manuscript|served on at least one of the research teams conducting the clinical trials discussed in this paper	contributed to the development of the manuscript	Wrote the paper	Writing - Original Draft	YES
3619032	23561044	All authors	2	contributed to the development of the manuscript|served on at least one of the research teams conducting the clinical trials discussed in this paper	served on at least one of the research teams conducting the clinical trials discussed in this paper	Performed the experiments	Investigation	YES
3619032	23561044	SM	2	convened the workshop that provided the impetus for the paper	convened the workshop that provided the impetus for the paper	-	-	NO
4419286	25960604	F.C.S.	2	contributed equally	contributed equally	-	-	NO
4419286	25960604	R.J.C.	2	contributed equally	contributed equally	-	-	NO
5447001	28611791	AD	2	written the manuscript and performed all analysis	written the manuscript and performed all analysis	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5447001	28611791	AS	2	conceptualized and guided the study	conceptualized and guided the study	Conceived and designed the experiments	Conceptualization|Supervision	YES
5447001	28611791	AT	2	conceptualized and guided the study	conceptualized and guided the study	Conceived and designed the experiments	Conceptualization|Supervision	YES
5447001	28611791	RS	2	helped in data analysis	helped in data analysis	Analyzed the data	Formal analysis	YES
5447001	28611791	SP	2	conceptualized and guided the study	conceptualized and guided the study	Conceived and designed the experiments	Conceptualization|Supervision	YES
6470818	30934535	N.K.	2	designed the experiments, performed the experimental work, analyzed the results, and wrote the manuscript	designed the experiments, performed the experimental work, analyzed the results, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
6470818	30934535	S.M.	2	performed part of the experimental work and/or analyzed the results	performed part of the experimental work and/or analyzed the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6470818	30934535	W.K.	2	conceptualized the study, wrote, and revised the manuscript	conceptualized the study, wrote, and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
4398493	25874453	DK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398493	25874453	DK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398493	25874453	DK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398493	25874453	DK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398493	25874453	HPB	PLoS5	Contributed reagents/materials/analysis tools|Helped with designing methods for preserving the emission and photoswitching properties of dye molecules embedded in resins	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398493	25874453	HPB	PLoS5	Contributed reagents/materials/analysis tools|Helped with designing methods for preserving the emission and photoswitching properties of dye molecules embedded in resins	Helped with designing methods for preserving the emission and photoswitching properties of dye molecules embedded in resins	Conceived and designed the experiments|Performed the experiments	Methodology	YES
4398493	25874453	MHE	PLoS5	Provided advice on the sample preparation for correlative fluorescence and electron microscopy	Provided advice on the sample preparation for correlative fluorescence and electron microscopy	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4398493	25874453	TJD	PLoS5	Provided advice on the sample preparation for correlative fluorescence and electron microscopy	Provided advice on the sample preparation for correlative fluorescence and electron microscopy	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4398493	25874453	XZ	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398493	25874453	XZ	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398493	25874453	YS	PLoS5	Contributed reagents/materials/analysis tools|Helped with designing methods for preserving the emission and photoswitching properties of dye molecules embedded in resins	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398493	25874453	YS	PLoS5	Contributed reagents/materials/analysis tools|Helped with designing methods for preserving the emission and photoswitching properties of dye molecules embedded in resins	Helped with designing methods for preserving the emission and photoswitching properties of dye molecules embedded in resins	Conceived and designed the experiments|Performed the experiments	Methodology	YES
3636421	23618365	AW	2	jointly designed the acasi survey	jointly designed the acasi survey	Conceived and designed the experiments|Performed the experiments	Investigation	YES
3636421	23618365	All authors	2	contributed during the editing process and approved the final, submitted manuscript	contributed during the editing process and approved the final, submitted manuscript	Wrote the paper	Writing - Review & Editing	YES
3636421	23618365	FM	2	conducted the statistical analysis	conducted the statistical analysis	Analyzed the data	Formal analysis	YES
3636421	23618365	MT	2	jointly designed the acasi survey	jointly designed the acasi survey	Conceived and designed the experiments|Performed the experiments	Investigation	YES
3636421	23618365	ND	2	jointly designed the acasi survey	jointly designed the acasi survey	Conceived and designed the experiments|Performed the experiments	Investigation	YES
3636421	23618365	NH	2	jointly designed the acasi survey|supervised the data analysis	jointly designed the acasi survey	Conceived and designed the experiments|Performed the experiments	Investigation	YES
3636421	23618365	NH	2	jointly designed the acasi survey|supervised the data analysis	supervised the data analysis	Analyzed the data	Formal analysis|Supervision	YES
3636421	23618365	RB	2	jointly designed the acasi survey|coordinated data collection|conducted the statistical analysis|wrote the first draft manuscript	jointly designed the acasi survey	Conceived and designed the experiments|Performed the experiments	Investigation	YES
3636421	23618365	RB	2	jointly designed the acasi survey|coordinated data collection|conducted the statistical analysis|wrote the first draft manuscript	coordinated data collection	Performed the experiments	Investigation|Project administration	YES
3636421	23618365	RB	2	jointly designed the acasi survey|coordinated data collection|conducted the statistical analysis|wrote the first draft manuscript	conducted the statistical analysis	Analyzed the data	Formal analysis	YES
3636421	23618365	RB	2	jointly designed the acasi survey|coordinated data collection|conducted the statistical analysis|wrote the first draft manuscript	wrote the first draft manuscript	Wrote the paper	Writing - Original Draft	YES
3636421	23618365	WD	2	jointly designed the acasi survey|wrote the first draft manuscript	jointly designed the acasi survey	Conceived and designed the experiments|Performed the experiments	Investigation	YES
3636421	23618365	WD	2	jointly designed the acasi survey|wrote the first draft manuscript	wrote the first draft manuscript	Wrote the paper	Writing - Original Draft	YES
6470838	30893910	B.S.S.	CRediT	Conceptualization|writing--original draft preparation	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6470838	30893910	B.S.S.	CRediT	Conceptualization|writing--original draft preparation	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6470838	30893910	E.K.	CRediT	methodology	methodology	Performed the experiments	Methodology	YES
6470838	30893910	H.S.	CRediT	methodology|visualization	methodology	Performed the experiments	Methodology	YES
6470838	30893910	H.S.	CRediT	methodology|visualization	visualization	Analyzed the data	Visualization	YES
6470838	30893910	K.N.	CRediT	Conceptualization	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6470838	30893910	M.K.	CRediT	Conceptualization|investigation|visualization	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6470838	30893910	M.K.	CRediT	Conceptualization|investigation|visualization	investigation	Performed the experiments	Investigation	YES
6470838	30893910	M.K.	CRediT	Conceptualization|investigation|visualization	visualization	Analyzed the data	Visualization	YES
6470838	30893910	W.K.	CRediT	Conceptualization|writing--original draft preparation	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6470838	30893910	W.K.	CRediT	Conceptualization|writing--original draft preparation	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
5447034	28611790	BC	2	contributed to the development of the initial miniaturized test and to the analysis of the enzymatic hydrolysis of cellulose	contributed to the development of the initial miniaturized test and to the analysis of the enzymatic hydrolysis of cellulose	Performed the experiments	Investigation	YES
5447034	28611790	JPC	2	coordinated the corresponding project and he supervised the development of the miniaturized tests	coordinated the corresponding project and he supervised the development of the miniaturized tests	-	Project administration|Supervision	YES
5447034	28611790	MB	2	contributed to the development of the initial project	contributed to the development of the initial project	-	-	NO
5447034	28611790	NB	2	developed the miniaturized test and performed the corresponding analyses|wrote the first draft of the manuscript and all authors contributed to the final version	developed the miniaturized test and performed the corresponding analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5447034	28611790	NB	2	developed the miniaturized test and performed the corresponding analyses|wrote the first draft of the manuscript and all authors contributed to the final version	wrote the first draft of the manuscript and all authors contributed to the final version	Wrote the paper	Writing - Original Draft	YES
5447034	28611790	SA	2	analyzed the data from the pilot tests|wrote the first draft of the manuscript and all authors contributed to the final version	analyzed the data from the pilot tests	Analyzed the data	Formal analysis	YES
5447034	28611790	SA	2	analyzed the data from the pilot tests|wrote the first draft of the manuscript and all authors contributed to the final version	wrote the first draft of the manuscript and all authors contributed to the final version	Wrote the paper	Writing - Original Draft	YES
5031345	27654580	BJH	2	supervised this project|gave important instructions on organizing and revising the manuscript	supervised this project	-	Supervision	YES
5031345	27654580	BJH	2	supervised this project|gave important instructions on organizing and revising the manuscript	gave important instructions on organizing and revising the manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
5031345	27654580	BR	2	algorithm, analysed the data and drafted the manuscript	algorithm, analysed the data and drafted the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Software|Writing - Original Draft	YES
5031345	27654580	MEG	2	contributed the valuable idea about hybrid scheme	contributed the valuable idea about hybrid scheme	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5031345	27654580	Y-PPC	2	supervised this project	supervised this project	-	Supervision	YES
5516244	27072626	Ana Casas	2	critically analysed the data, contributed to the drafting and review of the manuscript, and approved the final version for submission	critically analysed the data, contributed to the drafting and review of the manuscript, and approved the final version for submission	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5516244	27072626	Caroline Kennedy	2	critically analysed the data, contributed to the drafting and review of the manuscript, and approved the final version for submission	critically analysed the data, contributed to the drafting and review of the manuscript, and approved the final version for submission	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5516244	27072626	Catherine Deleplace	2	contributed to the design of this study|contributed to the collection of data|critically analysed the data, contributed to the drafting and review of the manuscript, and approved the final version for submission	contributed to the design of this study	Conceived and designed the experiments	Methodology	YES
5516244	27072626	Catherine Deleplace	2	contributed to the design of this study|contributed to the collection of data|critically analysed the data, contributed to the drafting and review of the manuscript, and approved the final version for submission	contributed to the collection of data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5516244	27072626	Catherine Deleplace	2	contributed to the design of this study|contributed to the collection of data|critically analysed the data, contributed to the drafting and review of the manuscript, and approved the final version for submission	critically analysed the data, contributed to the drafting and review of the manuscript, and approved the final version for submission	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5516244	27072626	Christian Jackisch	2	critically analysed the data, contributed to the drafting and review of the manuscript, and approved the final version for submission	critically analysed the data, contributed to the drafting and review of the manuscript, and approved the final version for submission	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5516244	27072626	Michele Cavo	2	critically analysed the data, contributed to the drafting and review of the manuscript, and approved the final version for submission	critically analysed the data, contributed to the drafting and review of the manuscript, and approved the final version for submission	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5516244	27072626	Paul Schoen	2	contributed to the design of this study|contributed to the collection of data|critically analysed the data, contributed to the drafting and review of the manuscript, and approved the final version for submission	contributed to the design of this study	Conceived and designed the experiments	Methodology	YES
5516244	27072626	Paul Schoen	2	contributed to the design of this study|contributed to the collection of data|critically analysed the data, contributed to the drafting and review of the manuscript, and approved the final version for submission	contributed to the collection of data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5516244	27072626	Paul Schoen	2	contributed to the design of this study|contributed to the collection of data|critically analysed the data, contributed to the drafting and review of the manuscript, and approved the final version for submission	critically analysed the data, contributed to the drafting and review of the manuscript, and approved the final version for submission	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5516244	27072626	Penella J. Woll	2	critically analysed the data, contributed to the drafting and review of the manuscript, and approved the final version for submission	critically analysed the data, contributed to the drafting and review of the manuscript, and approved the final version for submission	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5516244	27072626	Thierry Lebret	2	contributed to the design of this study|critically analysed the data, contributed to the drafting and review of the manuscript, and approved the final version for submission	contributed to the design of this study	Conceived and designed the experiments	Methodology	YES
5516244	27072626	Thierry Lebret	2	contributed to the design of this study|critically analysed the data, contributed to the drafting and review of the manuscript, and approved the final version for submission	critically analysed the data, contributed to the drafting and review of the manuscript, and approved the final version for submission	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
4398494	25875304	AB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398494	25875304	AB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398494	25875304	AB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398494	25875304	CG	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4398494	25875304	CG	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4398494	25875304	CG	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398494	25875304	GL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398494	25875304	GL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398494	25875304	GL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398494	25875304	GL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398494	25875304	GL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398494	25875304	KB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4398494	25875304	KB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4398494	25875304	KB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398494	25875304	OA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398494	25875304	OA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398494	25875304	OA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398494	25875304	OA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398494	25875304	OA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398494	25875304	PR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398494	25875304	PR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398494	25875304	PR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398494	25875304	RG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398494	25875304	RG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398494	25875304	RG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398494	25875304	RG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398494	25875304	RG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398494	25875304	SC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398494	25875304	SC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398494	25875304	SC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398494	25875304	SD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398494	25875304	SD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398494	25875304	SD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398494	25875304	SD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398494	25875304	SD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398494	25875304	TK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398494	25875304	TK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398494	25875304	TK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398494	25875304	TK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398494	25875304	TK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398494	25875304	VP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398494	25875304	VP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398494	25875304	VP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398494	25875304	VP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398494	25875304	VP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3638120	23621903	DR	2	have all read and approved the final manuscript	have all read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
3638120	23621903	GP	2	have all read and approved the final manuscript	have all read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
3638120	23621903	LF	2	have all read and approved the final manuscript	have all read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
3638120	23621903	SG	2	took the lead in all aspects of the paper writing	took the lead in all aspects of the paper writing	Wrote the paper	-	YES
3638120	23621903	TA	2	have all read and approved the final manuscript	have all read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5034428	27663193	AH	2	contributed to rna seq and genotyping analyses	contributed to rna seq and genotyping analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5034428	27663193	AK	2	performed phenotyping analysis	performed phenotyping analysis	Performed the experiments	Investigation	YES
5034428	27663193	AWS	2	designed the study and performed the interpretation	designed the study and performed the interpretation	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5034428	27663193	AZ	2	contributed to rna seq and genotyping analyses	contributed to rna seq and genotyping analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5034428	27663193	BD	2	performed phenotyping analysis	performed phenotyping analysis	Performed the experiments	Investigation	YES
5034428	27663193	DC	2	contributed to rna seq and genotyping analyses	contributed to rna seq and genotyping analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5034428	27663193	DPS	2	performed phenotyping analysis	performed phenotyping analysis	Performed the experiments	Investigation	YES
5034428	27663193	HW	2	contributed to rna seq and genotyping analyses	contributed to rna seq and genotyping analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5034428	27663193	J-JL	2	designed the study and performed the interpretation|drafted the manuscript	designed the study and performed the interpretation	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5034428	27663193	J-JL	2	designed the study and performed the interpretation|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5034428	27663193	RAS	2	designed the study and performed the interpretation	designed the study and performed the interpretation	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5034428	27663193	RNS	2	designed the study and performed the interpretation	designed the study and performed the interpretation	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5447041	28611805	AV	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5447041	28611805	All authors	PLoS52	contribute to data analysis and the writing of the manuscript	contribute to data analysis and the writing of the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
5447041	28611805	CP	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5447041	28611805	EE-J	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5447041	28611805	FC	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5447041	28611805	JB	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5447041	28611805	JS-S	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5447041	28611805	JV	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5447041	28611805	MB	PLoS52	planned, designed and supervised the research	planned, designed and supervised the research	Conceived and designed the experiments	Conceptualization|Methodology|Supervision	YES
5447041	28611805	NM-E	PLoS52	planned, designed and supervised the research	planned, designed and supervised the research	Conceived and designed the experiments	Conceptualization|Methodology|Supervision	YES
5447041	28611805	SO	PLoS52	planned, designed and supervised the research|performed the experiments	planned, designed and supervised the research	Conceived and designed the experiments	Conceptualization|Methodology|Supervision	YES
5447041	28611805	SO	PLoS52	planned, designed and supervised the research|performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5447041	28611805	VV	PLoS52	conceived the project|planned, designed and supervised the research	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5447041	28611805	VV	PLoS52	conceived the project|planned, designed and supervised the research	planned, designed and supervised the research	Conceived and designed the experiments	Conceptualization|Methodology|Supervision	YES
5447041	28611805	YK	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
4398495	25876061	BLH	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398495	25876061	BLH	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398495	25876061	FBW	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398495	25876061	FBW	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398495	25876061	NDFO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398495	25876061	NDFO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398495	25876061	NDFO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398495	25876061	NDFO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398495	25876061	NDFO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398495	25876061	RKR	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398495	25876061	RKR	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398495	25876061	VS	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398495	25876061	VS	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5447056	28611812	LR	2	designed the study, collected and analyzed the data and wrote the manuscript	designed the study, collected and analyzed the data and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
6470842	30845766	A.B.	PLoS52	performed the experiments|analyzed the data|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
6470842	30845766	A.B.	PLoS52	performed the experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
6470842	30845766	A.B.	PLoS52	performed the experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6470842	30845766	H.-J.M.	PLoS52	conceived and designed the experiments|analyzed the data|contributed reagents/materials|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6470842	30845766	H.-J.M.	PLoS52	conceived and designed the experiments|analyzed the data|contributed reagents/materials|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
6470842	30845766	H.-J.M.	PLoS52	conceived and designed the experiments|analyzed the data|contributed reagents/materials|wrote the paper	contributed reagents/materials	Contributed reagents/materials/analysis tools	Resources	YES
6470842	30845766	H.-J.M.	PLoS52	conceived and designed the experiments|analyzed the data|contributed reagents/materials|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6470842	30845766	K.-H.C.	PLoS52	contributed reagents/materials|wrote the paper	contributed reagents/materials	Contributed reagents/materials/analysis tools	Resources	YES
6470842	30845766	K.-H.C.	PLoS52	contributed reagents/materials|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6470842	30845766	S.-J.C.	PLoS52	conceived and designed the experiments|analyzed the data|contributed reagents/materials|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6470842	30845766	S.-J.C.	PLoS52	conceived and designed the experiments|analyzed the data|contributed reagents/materials|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
6470842	30845766	S.-J.C.	PLoS52	conceived and designed the experiments|analyzed the data|contributed reagents/materials|wrote the paper	contributed reagents/materials	Contributed reagents/materials/analysis tools	Resources	YES
6470842	30845766	S.-J.C.	PLoS52	conceived and designed the experiments|analyzed the data|contributed reagents/materials|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6470842	30845766	Y.-S.J.	PLoS52	performed the experiments|analyzed the data|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
6470842	30845766	Y.-S.J.	PLoS52	performed the experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
6470842	30845766	Y.-S.J.	PLoS52	performed the experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4547501	26321792	All authors	2	have given approval to the final version of the manuscript	have given approval to the final version of the manuscript	-	-	NO
4398496	25875959	DB	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398496	25875959	DB	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398496	25875959	HM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398496	25875959	HM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398496	25875959	HM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398496	25875959	HM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398496	25875959	HM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398496	25875959	MAM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398496	25875959	MAM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398496	25875959	MAM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398496	25875959	MAM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398496	25875959	MAM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398496	25875959	SW	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398496	25875959	SW	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5037627	27671088	AD	2	designed the algorithmic extensions to the set covering machine algorithm|conducted the experiments|evaluated the biological relevance of the models|wrote the manuscript	designed the algorithmic extensions to the set covering machine algorithm	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
5037627	27671088	AD	2	designed the algorithmic extensions to the set covering machine algorithm|conducted the experiments|evaluated the biological relevance of the models|wrote the manuscript	conducted the experiments	Performed the experiments	Investigation	YES
5037627	27671088	AD	2	designed the algorithmic extensions to the set covering machine algorithm|conducted the experiments|evaluated the biological relevance of the models|wrote the manuscript	evaluated the biological relevance of the models	Performed the experiments	Methodology	YES
5037627	27671088	AD	2	designed the algorithmic extensions to the set covering machine algorithm|conducted the experiments|evaluated the biological relevance of the models|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5037627	27671088	AMB	2	acquired and provided the c	acquired and provided the c	-	-	NO
5037627	27671088	FL	2	designed the algorithmic extensions to the set covering machine algorithm|wrote the manuscript	designed the algorithmic extensions to the set covering machine algorithm	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
5037627	27671088	FL	2	designed the algorithmic extensions to the set covering machine algorithm|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5037627	27671088	JC	2	evaluated the biological relevance of the models|wrote the manuscript	evaluated the biological relevance of the models	Performed the experiments	Methodology	YES
5037627	27671088	JC	2	evaluated the biological relevance of the models|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5037627	27671088	MD	2	evaluated the biological relevance of the models|acquired the data and prepared it for analysis|wrote the manuscript	evaluated the biological relevance of the models	Performed the experiments	Methodology	YES
5037627	27671088	MD	2	evaluated the biological relevance of the models|acquired the data and prepared it for analysis|wrote the manuscript	acquired the data and prepared it for analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5037627	27671088	MD	2	evaluated the biological relevance of the models|acquired the data and prepared it for analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5037627	27671088	MM	2	designed the algorithmic extensions to the set covering machine algorithm|wrote the manuscript	designed the algorithmic extensions to the set covering machine algorithm	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
5037627	27671088	MM	2	designed the algorithmic extensions to the set covering machine algorithm|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5037627	27671088	MT	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5037627	27671088	SG	2	designed the algorithmic extensions to the set covering machine algorithm|evaluated the biological relevance of the models|wrote the manuscript	designed the algorithmic extensions to the set covering machine algorithm	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
5037627	27671088	SG	2	designed the algorithmic extensions to the set covering machine algorithm|evaluated the biological relevance of the models|wrote the manuscript	evaluated the biological relevance of the models	Performed the experiments	Methodology	YES
5037627	27671088	SG	2	designed the algorithmic extensions to the set covering machine algorithm|evaluated the biological relevance of the models|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5037627	27671088	VL	2	acquired and provided the c	acquired and provided the c	-	-	NO
4415657	25961038	Galindo Garre	2	has performed the statistical analyses	has performed the statistical analyses	Analyzed the data	Formal analysis	YES
4415657	25961038	R. A. Goldbohm	2	have drafted the paper	have drafted the paper	Wrote the paper	Writing - Original Draft	YES
3651516	23663441	GB	2	made contributions to the study design, data collection tools, pilot study and participated in the acquisition of data	made contributions to the study design, data collection tools, pilot study and participated in the acquisition of data	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources	YES
3651516	23663441	HIV	2	made contributions to the study design, data collection tools, pilot study and participated in the acquisition of data	made contributions to the study design, data collection tools, pilot study and participated in the acquisition of data	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources	YES
3651516	23663441	JH	2	designed the study and wrote the protocol|did the analysis and interpretation of data|wrote the manuscript	designed the study and wrote the protocol	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3651516	23663441	JH	2	designed the study and wrote the protocol|did the analysis and interpretation of data|wrote the manuscript	did the analysis and interpretation of data	Analyzed the data	Formal analysis	YES
3651516	23663441	JH	2	designed the study and wrote the protocol|did the analysis and interpretation of data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3651516	23663441	LF	2	designed the study and wrote the protocol|took overall responsibility for the project|wrote the manuscript	designed the study and wrote the protocol	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3651516	23663441	LF	2	designed the study and wrote the protocol|took overall responsibility for the project|wrote the manuscript	took overall responsibility for the project	-	-	NO
3651516	23663441	LF	2	designed the study and wrote the protocol|took overall responsibility for the project|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3651516	23663441	LS	2	made contributions to the study design, data collection tools, pilot study and participated in the acquisition of data	made contributions to the study design, data collection tools, pilot study and participated in the acquisition of data	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources	YES
3651516	23663441	MJB	2	designed the study and wrote the protocol|took overall responsibility for the project|critically revised the manuscript and contributed important intellectual content	designed the study and wrote the protocol	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3651516	23663441	MJB	2	designed the study and wrote the protocol|took overall responsibility for the project|critically revised the manuscript and contributed important intellectual content	took overall responsibility for the project	-	-	NO
3651516	23663441	MJB	2	designed the study and wrote the protocol|took overall responsibility for the project|critically revised the manuscript and contributed important intellectual content	critically revised the manuscript and contributed important intellectual content	Wrote the paper	Writing - Review & Editing	YES
3651516	23663441	MR	2	made contributions to the study design, data collection tools, pilot study and participated in the acquisition of data	made contributions to the study design, data collection tools, pilot study and participated in the acquisition of data	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources	YES
3651516	23663441	Madrid Rapid	2	made contributions to the study design, data collection tools, pilot study and participated in the acquisition of data	made contributions to the study design, data collection tools, pilot study and participated in the acquisition of data	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources	YES
3651516	23663441	SFB	2	made contributions to the study design, data collection tools, pilot study and participated in the acquisition of data|did the analysis and interpretation of data|wrote the manuscript	made contributions to the study design, data collection tools, pilot study and participated in the acquisition of data	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources	YES
3651516	23663441	SFB	2	made contributions to the study design, data collection tools, pilot study and participated in the acquisition of data|did the analysis and interpretation of data|wrote the manuscript	did the analysis and interpretation of data	Analyzed the data	Formal analysis	YES
3651516	23663441	SFB	2	made contributions to the study design, data collection tools, pilot study and participated in the acquisition of data|did the analysis and interpretation of data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3651516	23663441	Testing Group	2	made contributions to the study design, data collection tools, pilot study and participated in the acquisition of data	made contributions to the study design, data collection tools, pilot study and participated in the acquisition of data	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources	YES
5447062	28611813	AM	2	organized and prepared some of the parts of this review, gave intellectual inputs and contributed to designing of the model|also approved the writeup	organized and prepared some of the parts of this review, gave intellectual inputs and contributed to designing of the model	Conceived and designed the experiments|Performed the experiments	Methodology	YES
5447062	28611813	AM	2	organized and prepared some of the parts of this review, gave intellectual inputs and contributed to designing of the model|also approved the writeup	also approved the writeup	Wrote the paper	-	YES
5447062	28611813	AR	2	did a substantial contribution to the design of this work outlay and important intellectual input in drafting of the work and final approval from all others	did a substantial contribution to the design of this work outlay and important intellectual input in drafting of the work and final approval from all others	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
5447062	28611813	GD	2	contributed for writing and editing the major part of the review and was involved in approving the final version that is to be published	contributed for writing and editing the major part of the review and was involved in approving the final version that is to be published	Wrote the paper	Writing - Review & Editing	YES
4398497	25875677	CWL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Read and approved the final manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4398497	25875677	CWL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Read and approved the final manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398497	25875677	CWL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Read and approved the final manuscript	Read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4398497	25875677	HRH	PLoS5	Conceived and designed the experiments|Read and approved the final manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398497	25875677	HRH	PLoS5	Conceived and designed the experiments|Read and approved the final manuscript	Read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4398497	25875677	JFH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Read and approved the final manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398497	25875677	JFH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Read and approved the final manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4398497	25875677	JFH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Read and approved the final manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4398497	25875677	JFH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Read and approved the final manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398497	25875677	JFH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Read and approved the final manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398497	25875677	JFH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Read and approved the final manuscript	Read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4398497	25875677	MCC	PLoS5	Performed the experiments|Read and approved the final manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4398497	25875677	MCC	PLoS5	Performed the experiments|Read and approved the final manuscript	Read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4398497	25875677	MHT	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Critically reviewed the manuscript, revised the manuscript, and approved the final manuscript as submitted|Read and approved the final manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4398497	25875677	MHT	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Critically reviewed the manuscript, revised the manuscript, and approved the final manuscript as submitted|Read and approved the final manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398497	25875677	MHT	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Critically reviewed the manuscript, revised the manuscript, and approved the final manuscript as submitted|Read and approved the final manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398497	25875677	MHT	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Critically reviewed the manuscript, revised the manuscript, and approved the final manuscript as submitted|Read and approved the final manuscript	Critically reviewed the manuscript, revised the manuscript, and approved the final manuscript as submitted	Wrote the paper	Writing - Review & Editing	YES
4398497	25875677	MHT	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Critically reviewed the manuscript, revised the manuscript, and approved the final manuscript as submitted|Read and approved the final manuscript	Read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4398497	25875677	PHY	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Read and approved the final manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4398497	25875677	PHY	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Read and approved the final manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398497	25875677	PHY	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Read and approved the final manuscript	Read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4398497	25875677	RHF	PLoS5	Performed the experiments|Read and approved the final manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4398497	25875677	RHF	PLoS5	Performed the experiments|Read and approved the final manuscript	Read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4398497	25875677	RL	PLoS5	Conceived and designed the experiments|Read and approved the final manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398497	25875677	RL	PLoS5	Conceived and designed the experiments|Read and approved the final manuscript	Read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4398497	25875677	SMC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Read and approved the final manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398497	25875677	SMC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Read and approved the final manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4398497	25875677	SMC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Read and approved the final manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398497	25875677	SMC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Read and approved the final manuscript	Read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
3656196	23680303	All authors	2	have contributed to the ideas discussed in this article and to the editing of this article	have contributed to the ideas discussed in this article and to the editing of this article	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
6470925	30823628	C.A.S.	CRediT	methodology|resources	methodology	Performed the experiments	Methodology	YES
6470925	30823628	C.A.S.	CRediT	methodology|resources	resources	Contributed reagents/materials/analysis tools	Resources	YES
6470925	30823628	C.V.	CRediT	validation|formal analysis|investigation	validation	Performed the experiments	Validation	YES
6470925	30823628	C.V.	CRediT	validation|formal analysis|investigation	formal analysis	Analyzed the data	Formal analysis	YES
6470925	30823628	C.V.	CRediT	validation|formal analysis|investigation	investigation	Performed the experiments	Investigation	YES
6470925	30823628	H.F.F.	CRediT	validation|formal analysis|investigation|writing--original draft preparation	validation	Performed the experiments	Validation	YES
6470925	30823628	H.F.F.	CRediT	validation|formal analysis|investigation|writing--original draft preparation	formal analysis	Analyzed the data	Formal analysis	YES
6470925	30823628	H.F.F.	CRediT	validation|formal analysis|investigation|writing--original draft preparation	investigation	Performed the experiments	Investigation	YES
6470925	30823628	H.F.F.	CRediT	validation|formal analysis|investigation|writing--original draft preparation	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6470925	30823628	J.O.M.	CRediT	Conceptualization|methodology|validation|resources|data curation|writing--review and editing|visualization|supervision|project administration|funding acquisition	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6470925	30823628	J.O.M.	CRediT	Conceptualization|methodology|validation|resources|data curation|writing--review and editing|visualization|supervision|project administration|funding acquisition	methodology	Performed the experiments	Methodology	YES
6470925	30823628	J.O.M.	CRediT	Conceptualization|methodology|validation|resources|data curation|writing--review and editing|visualization|supervision|project administration|funding acquisition	validation	Performed the experiments	Validation	YES
6470925	30823628	J.O.M.	CRediT	Conceptualization|methodology|validation|resources|data curation|writing--review and editing|visualization|supervision|project administration|funding acquisition	resources	Contributed reagents/materials/analysis tools	Resources	YES
6470925	30823628	J.O.M.	CRediT	Conceptualization|methodology|validation|resources|data curation|writing--review and editing|visualization|supervision|project administration|funding acquisition	data curation	Analyzed the data	Data curation	YES
6470925	30823628	J.O.M.	CRediT	Conceptualization|methodology|validation|resources|data curation|writing--review and editing|visualization|supervision|project administration|funding acquisition	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6470925	30823628	J.O.M.	CRediT	Conceptualization|methodology|validation|resources|data curation|writing--review and editing|visualization|supervision|project administration|funding acquisition	visualization	Analyzed the data	Visualization	YES
6470925	30823628	J.O.M.	CRediT	Conceptualization|methodology|validation|resources|data curation|writing--review and editing|visualization|supervision|project administration|funding acquisition	supervision	-	Supervision	YES
6470925	30823628	J.O.M.	CRediT	Conceptualization|methodology|validation|resources|data curation|writing--review and editing|visualization|supervision|project administration|funding acquisition	project administration	-	Project administration	YES
6470925	30823628	J.O.M.	CRediT	Conceptualization|methodology|validation|resources|data curation|writing--review and editing|visualization|supervision|project administration|funding acquisition	funding acquisition	-	Funding acquisition	YES
6470925	30823628	S.S.-R.	CRediT	Conceptualization|methodology|software|validation|formal analysis|investigation|resources|data curation|writing--original draft preparation|writing--review and editing|visualization	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6470925	30823628	S.S.-R.	CRediT	Conceptualization|methodology|software|validation|formal analysis|investigation|resources|data curation|writing--original draft preparation|writing--review and editing|visualization	methodology	Performed the experiments	Methodology	YES
6470925	30823628	S.S.-R.	CRediT	Conceptualization|methodology|software|validation|formal analysis|investigation|resources|data curation|writing--original draft preparation|writing--review and editing|visualization	software	Contributed reagents/materials/analysis tools	Software	YES
6470925	30823628	S.S.-R.	CRediT	Conceptualization|methodology|software|validation|formal analysis|investigation|resources|data curation|writing--original draft preparation|writing--review and editing|visualization	validation	Performed the experiments	Validation	YES
6470925	30823628	S.S.-R.	CRediT	Conceptualization|methodology|software|validation|formal analysis|investigation|resources|data curation|writing--original draft preparation|writing--review and editing|visualization	formal analysis	Analyzed the data	Formal analysis	YES
6470925	30823628	S.S.-R.	CRediT	Conceptualization|methodology|software|validation|formal analysis|investigation|resources|data curation|writing--original draft preparation|writing--review and editing|visualization	investigation	Performed the experiments	Investigation	YES
6470925	30823628	S.S.-R.	CRediT	Conceptualization|methodology|software|validation|formal analysis|investigation|resources|data curation|writing--original draft preparation|writing--review and editing|visualization	resources	Contributed reagents/materials/analysis tools	Resources	YES
6470925	30823628	S.S.-R.	CRediT	Conceptualization|methodology|software|validation|formal analysis|investigation|resources|data curation|writing--original draft preparation|writing--review and editing|visualization	data curation	Analyzed the data	Data curation	YES
6470925	30823628	S.S.-R.	CRediT	Conceptualization|methodology|software|validation|formal analysis|investigation|resources|data curation|writing--original draft preparation|writing--review and editing|visualization	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6470925	30823628	S.S.-R.	CRediT	Conceptualization|methodology|software|validation|formal analysis|investigation|resources|data curation|writing--original draft preparation|writing--review and editing|visualization	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6470925	30823628	S.S.-R.	CRediT	Conceptualization|methodology|software|validation|formal analysis|investigation|resources|data curation|writing--original draft preparation|writing--review and editing|visualization	visualization	Analyzed the data	Visualization	YES
6154010	29948336	All authors	2	have reviewed and approved the final text	have reviewed and approved the final text	Wrote the paper	Writing - Review & Editing	YES
6154010	29948336	CS	2	conceived the study, led the quantitative study design, data collection, analysis, and writing	conceived the study, led the quantitative study design, data collection, analysis, and writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology	YES
6154010	29948336	TS	2	contributed to the conceptualization of the paper and advised on statistical analyses	contributed to the conceptualization of the paper and advised on statistical analyses	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
5037629	27671213	AH	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
5037629	27671213	AH	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5037629	27671213	AT	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
5037629	27671213	AT	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5037629	27671213	EA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5037629	27671213	EA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
5037629	27671213	EA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5037629	27671213	EA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5037629	27671213	EA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5037629	27671213	EM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5037629	27671213	EM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5037629	27671213	EM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5037629	27671213	GA	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5037629	27671213	GY	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
5037629	27671213	GY	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5037629	27671213	GYAH	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5037629	27671213	ISK	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5037629	27671213	MK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5037629	27671213	MK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5037629	27671213	MK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5037629	27671213	MTML	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5037629	27671213	MTML	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5037629	27671213	MTML	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5037629	27671213	MTML	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5037629	27671213	TM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5037629	27671213	TM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5037629	27671213	TM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5037629	27671213	WA	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5037629	27671213	YZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5037629	27671213	ZP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5037629	27671213	ZP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
5037629	27671213	ZP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5037629	27671213	ZP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5447063	28611807	ID	PLoS52	performed the research|analyzed the data|wrote the paper	performed the research	Performed the experiments	Investigation	YES
5447063	28611807	ID	PLoS52	performed the research|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5447063	28611807	ID	PLoS52	performed the research|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5447063	28611807	JG	PLoS52	conceived and designed the study|wrote the paper	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5447063	28611807	JG	PLoS52	conceived and designed the study|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5447063	28611807	MK	PLoS52	conceived and designed the study|wrote the paper	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5447063	28611807	MK	PLoS52	conceived and designed the study|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5447063	28611807	PL	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5447063	28611807	RD	PLoS52	performed the research	performed the research	Performed the experiments	Investigation	YES
4398498	25874409	FA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398498	25874409	FA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398498	25874409	FA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398498	25874409	FA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398498	25874409	FA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398498	25874409	FRT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398498	25874409	FRT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398498	25874409	FRT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398498	25874409	FRT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398498	25874409	FRT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398498	25874409	MBK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398498	25874409	MBK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398498	25874409	MBK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398498	25874409	MBK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398498	25874409	MBK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398498	25874409	MF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398498	25874409	MF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398498	25874409	MF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398498	25874409	MF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398498	25874409	MF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398498	25874409	SH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398498	25874409	SH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398498	25874409	SH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398498	25874409	SH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398498	25874409	SH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6470926	30823389	B.-J.L.	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6470926	30823389	C.P.	PLoS52	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6470926	30823389	E.O.	PLoS52	assisted the interpretation of data and gave comments to revise this manuscript	assisted the interpretation of data and gave comments to revise this manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
6470926	30823389	J.-B.P.	PLoS52	assisted the interpretation of data and gave comments to revise this manuscript	assisted the interpretation of data and gave comments to revise this manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
6470926	30823389	J.-H.C.	PLoS52	assisted the interpretation of data and gave comments to revise this manuscript	assisted the interpretation of data and gave comments to revise this manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
6470926	30823389	N.M.M.	PLoS52	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6470926	30823389	P.H.-L.T.	PLoS52	contributed materials and analysis tools and advised the experimental design	contributed materials and analysis tools and advised the experimental design	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources	YES
6470926	30823389	Q.-R.C.	PLoS52	assisted the interpretation of data and gave comments to revise this manuscript	assisted the interpretation of data and gave comments to revise this manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
6470926	30823389	T.T.-D.T.	PLoS52	contributed materials and analysis tools and advised the experimental design	contributed materials and analysis tools and advised the experimental design	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources	YES
6470926	30823389	Y.S.	PLoS52	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3664300	23706178	JJA	2	conceptualized the article and all authors contributed to revisions and approved the final article	conceptualized the article and all authors contributed to revisions and approved the final article	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
6470966	30875948	D.-H.N.T.	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
6470966	30875948	D.C.N.	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
6470966	30875948	D.H.N.	CRediT	Original idea and supervision	Original idea and supervision	Conceived and designed the experiments	Conceptualization|Supervision	YES
6470966	30875948	H.V.-Q.	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
6470966	30875948	K.D.P.	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
6470966	30875948	L.G.B.	CRediT	Original idea and supervision	Original idea and supervision	Conceived and designed the experiments	Conceptualization|Supervision	YES
4398499	25875850	JK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398499	25875850	JK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398499	25875850	JK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398499	25875850	JP	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4398499	25875850	JP	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4398499	25875850	JV	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398499	25875850	JV	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398499	25875850	JV	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398499	25875850	PS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398499	25875850	PS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398499	25875850	PS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398499	25875850	PS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398499	25875850	TR	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4398499	25875850	TR	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4398499	25875850	ZD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398499	25875850	ZD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398499	25875850	ZD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398499	25875850	ZT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398499	25875850	ZT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398499	25875850	ZT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5447065	28611800	LC	PLoS52	designed research|provided samples|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
5447065	28611800	LC	PLoS52	designed research|provided samples|wrote the paper	provided samples	Contributed reagents/materials/analysis tools	Resources	YES
5447065	28611800	LC	PLoS52	designed research|provided samples|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5447065	28611800	TL	PLoS52	designed research	designed research	Conceived and designed the experiments	Methodology	YES
5447065	28611800	XG	PLoS52	designed research|performed research|performed bioinformatic analysis|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
5447065	28611800	XG	PLoS52	designed research|performed research|performed bioinformatic analysis|wrote the paper	performed research	Performed the experiments	Investigation	YES
5447065	28611800	XG	PLoS52	designed research|performed research|performed bioinformatic analysis|wrote the paper	performed bioinformatic analysis	Performed the experiments	Formal analysis|Investigation	YES
5447065	28611800	XG	PLoS52	designed research|performed research|performed bioinformatic analysis|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5447065	28611800	XZ	PLoS52	designed research|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
5447065	28611800	XZ	PLoS52	designed research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5447065	28611800	ZM	PLoS52	performed bioinformatic analysis	performed bioinformatic analysis	Performed the experiments	Formal analysis|Investigation	YES
5447065	28611800	ZZ	PLoS52	performed research|performed bioinformatic analysis	performed research	Performed the experiments	Investigation	YES
5447065	28611800	ZZ	PLoS52	performed research|performed bioinformatic analysis	performed bioinformatic analysis	Performed the experiments	Formal analysis|Investigation	YES
5037894	27671367	LMJS	2	conceived and supervised the work and wrote the manuscript	conceived and supervised the work and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Supervision|Writing - Original Draft	YES
5037894	27671367	LS	2	conceived and supervised the work, performed some of the analyses and wrote the manuscript	conceived and supervised the work, performed some of the analyses and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Supervision|Writing - Original Draft	YES
5037894	27671367	MJH	2	performed some of the bioinformatics analysis and led the sequencing	performed some of the bioinformatics analysis and led the sequencing	Performed the experiments	Formal analysis|Investigation	YES
5037894	27671367	MJV	2	carried out the bioinformatics analysis	carried out the bioinformatics analysis	Performed the experiments	Formal analysis|Investigation	YES
5037894	27671367	MMO	2	conceived, designed and performed the experiment, analysed some of the data and wrote the manuscript	conceived, designed and performed the experiment, analysed some of the data and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5037894	27671367	MTS	2	carried out the bioinformatics analysis	carried out the bioinformatics analysis	Performed the experiments	Formal analysis|Investigation	YES
5037894	27671367	RK	2	did some of the rna extraction and cdna library preparation	did some of the rna extraction and cdna library preparation	Performed the experiments	Investigation	YES
3665848	23714198	AMG	2	contributed significantly to the design and conduct of the systematic search and review of articles, extraction and analysis of data, and preparation of the manuscript	contributed significantly to the design and conduct of the systematic search and review of articles, extraction and analysis of data, and preparation of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
3665848	23714198	MLS	2	contributed to the review of articles, extraction and analysis of data, and contributed significantly to the preparation and writing of the manuscript	contributed to the review of articles, extraction and analysis of data, and contributed significantly to the preparation and writing of the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft|Writing - Review & Editing	YES
3665848	23714198	POG	2	contributed to the systematic search and review of articles and the preparation and writing of the manuscript	contributed to the systematic search and review of articles and the preparation and writing of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3665848	23714198	RCV	2	designed the systematic review, contributed significantly to the systematic search and review of articles and was the primary writer of the manuscript	designed the systematic review, contributed significantly to the systematic search and review of articles and was the primary writer of the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3665848	23714198	WMN	2	contributed to the systematic review of articles and the preparation and writing of the manuscript	contributed to the systematic review of articles and the preparation and writing of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3672445	23735817	EH	2	contributed to analysis and interpretation of data	contributed to analysis and interpretation of data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
3672445	23735817	ME	2	contributed to conception and design|contributed to analysis and interpretation of data|revised this article critically for important intellectual content	contributed to conception and design	Conceived and designed the experiments	Conceptualization	YES
3672445	23735817	ME	2	contributed to conception and design|contributed to analysis and interpretation of data|revised this article critically for important intellectual content	contributed to analysis and interpretation of data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
3672445	23735817	ME	2	contributed to conception and design|contributed to analysis and interpretation of data|revised this article critically for important intellectual content	revised this article critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
3672445	23735817	SC	2	contributed to conception and design|contributed to analysis and interpretation of data|revised this article critically for important intellectual content	contributed to conception and design	Conceived and designed the experiments	Conceptualization	YES
3672445	23735817	SC	2	contributed to conception and design|contributed to analysis and interpretation of data|revised this article critically for important intellectual content	contributed to analysis and interpretation of data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
3672445	23735817	SC	2	contributed to conception and design|contributed to analysis and interpretation of data|revised this article critically for important intellectual content	revised this article critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
3672445	23735817	SV	2	contributed to conception and design|contributed to analysis and interpretation of data	contributed to conception and design	Conceived and designed the experiments	Conceptualization	YES
3672445	23735817	SV	2	contributed to conception and design|contributed to analysis and interpretation of data	contributed to analysis and interpretation of data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5447073	28611793	DZ	2	performed the experiment of gene function identification|wrote and critically reviewed this article	performed the experiment of gene function identification	Performed the experiments	Investigation	YES
5447073	28611793	DZ	2	performed the experiment of gene function identification|wrote and critically reviewed this article	wrote and critically reviewed this article	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5447073	28611793	JC	2	performed the microarray analysis and gene cloning|wrote and critically reviewed this article	performed the microarray analysis and gene cloning	Performed the experiments	Investigation	YES
5447073	28611793	JC	2	performed the microarray analysis and gene cloning|wrote and critically reviewed this article	wrote and critically reviewed this article	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5447073	28611793	NL	2	performed the experiment of gene function identification	performed the experiment of gene function identification	Performed the experiments	Investigation	YES
5447073	28611793	TL	2	performed the experiment of gene function identification	performed the experiment of gene function identification	Performed the experiments	Investigation	YES
5447073	28611793	VG	2	wrote and critically reviewed this article	wrote and critically reviewed this article	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5447073	28611793	XD	2	designed the experiments and revised the paper	designed the experiments and revised the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5447073	28611793	XM	2	performed the experiment of gene function identification	performed the experiment of gene function identification	Performed the experiments	Investigation	YES
4398500	25874795	HVC	PLoS5	Conceived and designed the experiments|Read, commented on and approved manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398500	25874795	HVC	PLoS5	Conceived and designed the experiments|Read, commented on and approved manuscript	Read, commented on and approved manuscript	-	-	NO
4398500	25874795	KMK	PLoS5	Conceived and designed the experiments|Performed the experiments|Read, commented on and approved manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398500	25874795	KMK	PLoS5	Conceived and designed the experiments|Performed the experiments|Read, commented on and approved manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4398500	25874795	KMK	PLoS5	Conceived and designed the experiments|Performed the experiments|Read, commented on and approved manuscript	Read, commented on and approved manuscript	-	-	NO
4398500	25874795	SKK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Read, commented on and approved manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398500	25874795	SKK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Read, commented on and approved manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4398500	25874795	SKK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Read, commented on and approved manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398500	25874795	SKK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Read, commented on and approved manuscript	Read, commented on and approved manuscript	-	-	NO
4806310	27019548	All authors	2	have given approval to the final version of the manuscript	have given approval to the final version of the manuscript	-	-	NO
6471061	30893796	A.A.	CRediT	Methodology|Software|Validation|Formal analysis|Investigation|Data curation|Writing-original draft preparation	Methodology	Performed the experiments	Methodology	YES
6471061	30893796	A.A.	CRediT	Methodology|Software|Validation|Formal analysis|Investigation|Data curation|Writing-original draft preparation	Software	Contributed reagents/materials/analysis tools	Software	YES
6471061	30893796	A.A.	CRediT	Methodology|Software|Validation|Formal analysis|Investigation|Data curation|Writing-original draft preparation	Validation	Performed the experiments	Validation	YES
6471061	30893796	A.A.	CRediT	Methodology|Software|Validation|Formal analysis|Investigation|Data curation|Writing-original draft preparation	Formal analysis	Analyzed the data	Formal analysis	YES
6471061	30893796	A.A.	CRediT	Methodology|Software|Validation|Formal analysis|Investigation|Data curation|Writing-original draft preparation	Investigation	Performed the experiments	Investigation	YES
6471061	30893796	A.A.	CRediT	Methodology|Software|Validation|Formal analysis|Investigation|Data curation|Writing-original draft preparation	Data curation	Analyzed the data	Data curation	YES
6471061	30893796	A.A.	CRediT	Methodology|Software|Validation|Formal analysis|Investigation|Data curation|Writing-original draft preparation	Writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
6471061	30893796	B.R.-A.	CRediT	Methodology|Writing-original draft preparation	Methodology	Performed the experiments	Methodology	YES
6471061	30893796	B.R.-A.	CRediT	Methodology|Writing-original draft preparation	Writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
6471061	30893796	D.V.	CRediT	Conceptualization|Methodology|Software|Formal analysis|Resources|Writing-original draft preparation|Writing-review & editing|Supervision	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6471061	30893796	D.V.	CRediT	Conceptualization|Methodology|Software|Formal analysis|Resources|Writing-original draft preparation|Writing-review & editing|Supervision	Methodology	Performed the experiments	Methodology	YES
6471061	30893796	D.V.	CRediT	Conceptualization|Methodology|Software|Formal analysis|Resources|Writing-original draft preparation|Writing-review & editing|Supervision	Software	Contributed reagents/materials/analysis tools	Software	YES
6471061	30893796	D.V.	CRediT	Conceptualization|Methodology|Software|Formal analysis|Resources|Writing-original draft preparation|Writing-review & editing|Supervision	Formal analysis	Analyzed the data	Formal analysis	YES
6471061	30893796	D.V.	CRediT	Conceptualization|Methodology|Software|Formal analysis|Resources|Writing-original draft preparation|Writing-review & editing|Supervision	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6471061	30893796	D.V.	CRediT	Conceptualization|Methodology|Software|Formal analysis|Resources|Writing-original draft preparation|Writing-review & editing|Supervision	Writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
6471061	30893796	D.V.	CRediT	Conceptualization|Methodology|Software|Formal analysis|Resources|Writing-original draft preparation|Writing-review & editing|Supervision	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6471061	30893796	D.V.	CRediT	Conceptualization|Methodology|Software|Formal analysis|Resources|Writing-original draft preparation|Writing-review & editing|Supervision	Supervision	-	Supervision	YES
6471061	30893796	J.M.	CRediT	Methodology|Validation|Formal analysis|Investigation|Data curation	Methodology	Performed the experiments	Methodology	YES
6471061	30893796	J.M.	CRediT	Methodology|Validation|Formal analysis|Investigation|Data curation	Validation	Performed the experiments	Validation	YES
6471061	30893796	J.M.	CRediT	Methodology|Validation|Formal analysis|Investigation|Data curation	Formal analysis	Analyzed the data	Formal analysis	YES
6471061	30893796	J.M.	CRediT	Methodology|Validation|Formal analysis|Investigation|Data curation	Investigation	Performed the experiments	Investigation	YES
6471061	30893796	J.M.	CRediT	Methodology|Validation|Formal analysis|Investigation|Data curation	Data curation	Analyzed the data	Data curation	YES
4898166	27160659	Annette Dalrymple	2	designed the study|drafted the manuscript and prepared the figures	designed the study	Conceived and designed the experiments	Methodology	YES
4898166	27160659	Annette Dalrymple	2	designed the study|drafted the manuscript and prepared the figures	drafted the manuscript and prepared the figures	Wrote the paper	Visualization|Writing - Original Draft	YES
4898166	27160659	Ansgar Buttner	2	analyzed the histopathology data and prepared the corresponding tables and figures	analyzed the histopathology data and prepared the corresponding tables and figures	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
4898166	27160659	Clive Meredith	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
4898166	27160659	David Thorne	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
4898166	27160659	David Walker	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
4898166	27160659	Debbie Dillon	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
4898166	27160659	Patricia Ordonez	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
3676535	23746302	ACD	PLoS52	conceived and designed the study|wrote the paper	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3676535	23746302	ACD	PLoS52	conceived and designed the study|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3676535	23746302	CD	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
3676535	23746302	ICB	PLoS52	conceived and designed the study|wrote the paper	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3676535	23746302	ICB	PLoS52	conceived and designed the study|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3676535	23746302	MAP	PLoS52	conceived and designed the study|analyzed the data|wrote the paper	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3676535	23746302	MAP	PLoS52	conceived and designed the study|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
3676535	23746302	MAP	PLoS52	conceived and designed the study|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3676535	23746302	MMA	PLoS52	conceived and designed the study|wrote the paper	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3676535	23746302	MMA	PLoS52	conceived and designed the study|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3676535	23746302	RM	PLoS52	conceived and designed the study|coordinated participants recruitment	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3676535	23746302	RM	PLoS52	conceived and designed the study|coordinated participants recruitment	coordinated participants recruitment	Performed the experiments	Investigation|Project administration	YES
3676535	23746302	VB	PLoS52	conceived and designed the study|coordinated participants recruitment	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3676535	23746302	VB	PLoS52	conceived and designed the study|coordinated participants recruitment	coordinated participants recruitment	Performed the experiments	Investigation|Project administration	YES
5447074	28611794	All authors	2	approved the final manuscript	approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5447074	28611794	CR	2	revised manuscript and polish language	revised manuscript and polish language	Wrote the paper	Writing - Review & Editing	YES
5447074	28611794	HW	2	planned and designed the research|revised manuscript and polish language	planned and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5447074	28611794	HW	2	planned and designed the research|revised manuscript and polish language	revised manuscript and polish language	Wrote the paper	Writing - Review & Editing	YES
5447074	28611794	JL	2	planned and designed the research	planned and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5447074	28611794	YZ	2	planned and designed the research|performed the experiment, analyzed the data and wrote the manuscript	planned and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5447074	28611794	YZ	2	planned and designed the research|performed the experiment, analyzed the data and wrote the manuscript	performed the experiment, analyzed the data and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5039799	27678067	GMG	2	interpreted the data and critically revised the manuscript	interpreted the data and critically revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5039799	27678067	LV	2	interpreted the data and critically revised the manuscript	interpreted the data and critically revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5039799	27678067	MY	2	supervised the project|interpreted the data and critically revised the manuscript	supervised the project	-	Supervision	YES
5039799	27678067	MY	2	supervised the project|interpreted the data and critically revised the manuscript	interpreted the data and critically revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5039799	27678067	MZ	2	designed and/or performed experiments	designed and/or performed experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5039799	27678067	WC	2	designed and/or performed experiments	designed and/or performed experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5039799	27678067	WH	2	carried out the bioinformatics analysis|interpreted the data and critically revised the manuscript	carried out the bioinformatics analysis	Performed the experiments	Formal analysis|Investigation	YES
5039799	27678067	WH	2	carried out the bioinformatics analysis|interpreted the data and critically revised the manuscript	interpreted the data and critically revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5039799	27678067	WQ	2	designed and/or performed experiments|drafted the manuscript|carried out the bioinformatics analysis|interpreted the data and critically revised the manuscript	designed and/or performed experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5039799	27678067	WQ	2	designed and/or performed experiments|drafted the manuscript|carried out the bioinformatics analysis|interpreted the data and critically revised the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5039799	27678067	WQ	2	designed and/or performed experiments|drafted the manuscript|carried out the bioinformatics analysis|interpreted the data and critically revised the manuscript	carried out the bioinformatics analysis	Performed the experiments	Formal analysis|Investigation	YES
5039799	27678067	WQ	2	designed and/or performed experiments|drafted the manuscript|carried out the bioinformatics analysis|interpreted the data and critically revised the manuscript	interpreted the data and critically revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5039799	27678067	XM	2	carried out the bioinformatics analysis|interpreted the data and critically revised the manuscript	carried out the bioinformatics analysis	Performed the experiments	Formal analysis|Investigation	YES
5039799	27678067	XM	2	carried out the bioinformatics analysis|interpreted the data and critically revised the manuscript	interpreted the data and critically revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4398515	25874963	CL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398515	25874963	CL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398515	25874963	CL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398515	25874963	EKT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398515	25874963	EKT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398515	25874963	EKT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398515	25874963	EKT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398515	25874963	EKT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398515	25874963	ICE	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398515	25874963	ICE	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6471120	30934594	A.B.-D.	CRediT	Conceptualization|formal analysis|resources|data curation|writing--original draft preparation|writing--review and editing|supervision|project administration	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6471120	30934594	A.B.-D.	CRediT	Conceptualization|formal analysis|resources|data curation|writing--original draft preparation|writing--review and editing|supervision|project administration	formal analysis	Analyzed the data	Formal analysis	YES
6471120	30934594	A.B.-D.	CRediT	Conceptualization|formal analysis|resources|data curation|writing--original draft preparation|writing--review and editing|supervision|project administration	resources	Contributed reagents/materials/analysis tools	Resources	YES
6471120	30934594	A.B.-D.	CRediT	Conceptualization|formal analysis|resources|data curation|writing--original draft preparation|writing--review and editing|supervision|project administration	data curation	Analyzed the data	Data curation	YES
6471120	30934594	A.B.-D.	CRediT	Conceptualization|formal analysis|resources|data curation|writing--original draft preparation|writing--review and editing|supervision|project administration	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6471120	30934594	A.B.-D.	CRediT	Conceptualization|formal analysis|resources|data curation|writing--original draft preparation|writing--review and editing|supervision|project administration	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6471120	30934594	A.B.-D.	CRediT	Conceptualization|formal analysis|resources|data curation|writing--original draft preparation|writing--review and editing|supervision|project administration	supervision	-	Supervision	YES
6471120	30934594	A.B.-D.	CRediT	Conceptualization|formal analysis|resources|data curation|writing--original draft preparation|writing--review and editing|supervision|project administration	project administration	-	Project administration	YES
6471120	30934594	D.L.P.	CRediT	Conceptualization|formal analysis|resources|writing--original draft preparation|writing--review and editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6471120	30934594	D.L.P.	CRediT	Conceptualization|formal analysis|resources|writing--original draft preparation|writing--review and editing	formal analysis	Analyzed the data	Formal analysis	YES
6471120	30934594	D.L.P.	CRediT	Conceptualization|formal analysis|resources|writing--original draft preparation|writing--review and editing	resources	Contributed reagents/materials/analysis tools	Resources	YES
6471120	30934594	D.L.P.	CRediT	Conceptualization|formal analysis|resources|writing--original draft preparation|writing--review and editing	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6471120	30934594	D.L.P.	CRediT	Conceptualization|formal analysis|resources|writing--original draft preparation|writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6471120	30934594	D.T.-M.	CRediT	Conceptualization|methodology|formal analysis|investigation|resources|writing--review and editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6471120	30934594	D.T.-M.	CRediT	Conceptualization|methodology|formal analysis|investigation|resources|writing--review and editing	methodology	Performed the experiments	Methodology	YES
6471120	30934594	D.T.-M.	CRediT	Conceptualization|methodology|formal analysis|investigation|resources|writing--review and editing	formal analysis	Analyzed the data	Formal analysis	YES
6471120	30934594	D.T.-M.	CRediT	Conceptualization|methodology|formal analysis|investigation|resources|writing--review and editing	investigation	Performed the experiments	Investigation	YES
6471120	30934594	D.T.-M.	CRediT	Conceptualization|methodology|formal analysis|investigation|resources|writing--review and editing	resources	Contributed reagents/materials/analysis tools	Resources	YES
6471120	30934594	D.T.-M.	CRediT	Conceptualization|methodology|formal analysis|investigation|resources|writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6471120	30934594	D.T.M.	CRediT	writing--original draft preparation	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6471120	30934594	I.Z.	CRediT	writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6471120	30934594	I.Z.C.	CRediT	project administration|funding acquisition	project administration	-	Project administration	YES
6471120	30934594	I.Z.C.	CRediT	project administration|funding acquisition	funding acquisition	-	Funding acquisition	YES
4836877	27110064	All authors	2	have given approval to the final version of the manuscript	have given approval to the final version of the manuscript	-	-	NO
5039875	27678198	All authors	2	tested the software and web portal	tested the software and web portal	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5039875	27678198	QZ	2	contributed to portal development	contributed to portal development	-	-	NO
5039875	27678198	RAR	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5039875	27678198	RWL	2	conceived the project	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5039875	27678198	WL	2	conceived the project|implemented the system|wrote the manuscript	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5039875	27678198	WL	2	conceived the project|implemented the system|wrote the manuscript	implemented the system	Performed the experiments	Investigation	YES
5039875	27678198	WL	2	conceived the project|implemented the system|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5039875	27678198	YJ	2	contributed to portal development	contributed to portal development	-	-	NO
3679527	23755857	All	2	investigators contributed to concept of the study	investigators contributed to concept of the study	Conceived and designed the experiments	Conceptualization	YES
3679527	23755857	All other authors	2	critically read and approved the final manuscript	critically read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
3679527	23755857	BS	2	participated in study design and edited the manuscript	participated in study design and edited the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
3679527	23755857	DN	2	supervised data analysis and revised the manuscript	supervised data analysis and revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Supervision|Writing - Review & Editing	YES
3679527	23755857	HB	2	conducted statistical analysis and edited the manuscript	conducted statistical analysis and edited the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
3679527	23755857	ML	2	supervised data analysis and revised the manuscript	supervised data analysis and revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Supervision|Writing - Review & Editing	YES
3679527	23755857	RP	2	analyzed data and wrote the manuscript	analyzed data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4398536	25875210	ES	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398536	25875210	ES	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398536	25875210	ES	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398536	25875210	MC	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398536	25875210	MC	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398536	25875210	PB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398536	25875210	PB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398536	25875210	PB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5447075	28611809	CB	2	performed most of the experiments|supervised the experiments|designed the experiments and analyzed the data|conceived and supervised the project|wrote the article with contributions of all the authors	performed most of the experiments	Performed the experiments	Investigation	YES
5447075	28611809	CB	2	performed most of the experiments|supervised the experiments|designed the experiments and analyzed the data|conceived and supervised the project|wrote the article with contributions of all the authors	supervised the experiments	-	Supervision	YES
5447075	28611809	CB	2	performed most of the experiments|supervised the experiments|designed the experiments and analyzed the data|conceived and supervised the project|wrote the article with contributions of all the authors	designed the experiments and analyzed the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5447075	28611809	CB	2	performed most of the experiments|supervised the experiments|designed the experiments and analyzed the data|conceived and supervised the project|wrote the article with contributions of all the authors	conceived and supervised the project	Conceived and designed the experiments	Conceptualization|Supervision	YES
5447075	28611809	CB	2	performed most of the experiments|supervised the experiments|designed the experiments and analyzed the data|conceived and supervised the project|wrote the article with contributions of all the authors	wrote the article with contributions of all the authors	Wrote the paper	Writing - Original Draft	YES
5447075	28611809	DC	2	performed most of the experiments	performed most of the experiments	Performed the experiments	Investigation	YES
5447075	28611809	FI	2	performed most of the experiments|designed the experiments and analyzed the data|wrote the article with contributions of all the authors	performed most of the experiments	Performed the experiments	Investigation	YES
5447075	28611809	FI	2	performed most of the experiments|designed the experiments and analyzed the data|wrote the article with contributions of all the authors	designed the experiments and analyzed the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5447075	28611809	FI	2	performed most of the experiments|designed the experiments and analyzed the data|wrote the article with contributions of all the authors	wrote the article with contributions of all the authors	Wrote the paper	Writing - Original Draft	YES
5447075	28611809	JB	2	designed the experiments and analyzed the data	designed the experiments and analyzed the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5447075	28611809	KT	2	provided technical assistance to lb, fi, and cb	provided technical assistance to lb, fi, and cb	Performed the experiments	Investigation	YES
5447075	28611809	LB	2	performed most of the experiments|supervised the experiments|designed the experiments and analyzed the data	performed most of the experiments	Performed the experiments	Investigation	YES
5447075	28611809	LB	2	performed most of the experiments|supervised the experiments|designed the experiments and analyzed the data	supervised the experiments	-	Supervision	YES
5447075	28611809	LB	2	performed most of the experiments|supervised the experiments|designed the experiments and analyzed the data	designed the experiments and analyzed the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5447075	28611809	LF	2	supervised the experiments	supervised the experiments	-	Supervision	YES
5447075	28611809	NE	2	performed most of the experiments|provided technical assistance to lb, fi, and cb	performed most of the experiments	Performed the experiments	Investigation	YES
5447075	28611809	NE	2	performed most of the experiments|provided technical assistance to lb, fi, and cb	provided technical assistance to lb, fi, and cb	Performed the experiments	Investigation	YES
5447075	28611809	SC	2	supervised the experiments|provided technical assistance to lb, fi, and cb	supervised the experiments	-	Supervision	YES
5447075	28611809	SC	2	supervised the experiments|provided technical assistance to lb, fi, and cb	provided technical assistance to lb, fi, and cb	Performed the experiments	Investigation	YES
5447075	28611809	SP	2	provided technical assistance to lb, fi, and cb	provided technical assistance to lb, fi, and cb	Performed the experiments	Investigation	YES
4398537	25874447	CLB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398537	25874447	CLB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398537	25874447	CLB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398537	25874447	CLB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398537	25874447	CLB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398537	25874447	CLM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398537	25874447	CLM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398537	25874447	CLM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398537	25874447	CLM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398537	25874447	CLM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4862384	27182110	A.B.	2	performed the eht experiment|contributed to manuscript writing	performed the eht experiment	Performed the experiments	Investigation	YES
4862384	27182110	A.B.	2	performed the eht experiment|contributed to manuscript writing	contributed to manuscript writing	Wrote the paper	Writing - Original Draft	YES
4862384	27182110	A.F.-P.	2	contributed to the preparation of the sample|contributed to manuscript writing	contributed to the preparation of the sample	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4862384	27182110	A.F.-P.	2	contributed to the preparation of the sample|contributed to manuscript writing	contributed to manuscript writing	Wrote the paper	Writing - Original Draft	YES
4862384	27182110	A.L.	2	performed the magnetic stray field reconstruction|contributed to manuscript writing	performed the magnetic stray field reconstruction	Performed the experiments	Investigation	YES
4862384	27182110	A.L.	2	performed the magnetic stray field reconstruction|contributed to manuscript writing	contributed to manuscript writing	Wrote the paper	Writing - Original Draft	YES
4862384	27182110	All the authors	2	discussed the results and commented on the manuscript	discussed the results and commented on the manuscript	-	-	NO
4862384	27182110	D.W.	2	performed the eht experiment|aligned, reconstructed, and evaluated the 3d data|wrote the manuscript	performed the eht experiment	Performed the experiments	Investigation	YES
4862384	27182110	D.W.	2	performed the eht experiment|aligned, reconstructed, and evaluated the 3d data|wrote the manuscript	aligned, reconstructed, and evaluated the 3d data	Performed the experiments	Investigation	YES
4862384	27182110	D.W.	2	performed the eht experiment|aligned, reconstructed, and evaluated the 3d data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4862384	27182110	E.J.	2	performed the eht experiment	performed the eht experiment	Performed the experiments	Investigation	YES
4862384	27182110	E.S.	2	contributed to manuscript writing|initiated the eht study	contributed to manuscript writing	Wrote the paper	Writing - Original Draft	YES
4862384	27182110	E.S.	2	contributed to manuscript writing|initiated the eht study	initiated the eht study	Conceived and designed the experiments	Conceptualization	YES
4862384	27182110	H.L.	2	initiated the eht study	initiated the eht study	Conceived and designed the experiments	Conceptualization	YES
4862384	27182110	J.M.D.T.	2	contributed to the preparation of the sample	contributed to the preparation of the sample	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4862384	27182110	L.A.R.	2	performed the eht experiment|performed the micromagnetic simulation|contributed to manuscript writing	performed the eht experiment	Performed the experiments	Investigation	YES
4862384	27182110	L.A.R.	2	performed the eht experiment|performed the micromagnetic simulation|contributed to manuscript writing	performed the micromagnetic simulation	Performed the experiments	Formal analysis|Investigation	YES
4862384	27182110	L.A.R.	2	performed the eht experiment|performed the micromagnetic simulation|contributed to manuscript writing	contributed to manuscript writing	Wrote the paper	Writing - Original Draft	YES
4862384	27182110	L.S.	2	prepared the sample|contributed to manuscript writing	prepared the sample	Performed the experiments	Investigation	YES
4862384	27182110	L.S.	2	prepared the sample|contributed to manuscript writing	contributed to manuscript writing	Wrote the paper	Writing - Original Draft	YES
4862384	27182110	S.B.	2	contributed to manuscript writing|initiated the eht study	contributed to manuscript writing	Wrote the paper	Writing - Original Draft	YES
4862384	27182110	S.B.	2	contributed to manuscript writing|initiated the eht study	initiated the eht study	Conceived and designed the experiments	Conceptualization	YES
3687072	23782480	All authors	2	contributed to the content and design of this review and have read and approved the final version	contributed to the content and design of this review and have read and approved the final version	Conceived and designed the experiments	-	YES
6471170	30832339	K.E.F.	CRediT	Conceptualization|Formal analysis|Investigation|Visualization|Writing--original draft|Writing--review & editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6471170	30832339	K.E.F.	CRediT	Conceptualization|Formal analysis|Investigation|Visualization|Writing--original draft|Writing--review & editing	Formal analysis	Analyzed the data	Formal analysis	YES
6471170	30832339	K.E.F.	CRediT	Conceptualization|Formal analysis|Investigation|Visualization|Writing--original draft|Writing--review & editing	Investigation	Performed the experiments	Investigation	YES
6471170	30832339	K.E.F.	CRediT	Conceptualization|Formal analysis|Investigation|Visualization|Writing--original draft|Writing--review & editing	Visualization	Analyzed the data	Visualization	YES
6471170	30832339	K.E.F.	CRediT	Conceptualization|Formal analysis|Investigation|Visualization|Writing--original draft|Writing--review & editing	Writing--original draft	Wrote the paper	Writing - Original Draft	YES
6471170	30832339	K.E.F.	CRediT	Conceptualization|Formal analysis|Investigation|Visualization|Writing--original draft|Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6471170	30832339	M.E.M.	CRediT	Conceptualization|Funding acquisition|Investigation|Project administration|Resources|Supervision|Visualization|Writing--review & editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6471170	30832339	M.E.M.	CRediT	Conceptualization|Funding acquisition|Investigation|Project administration|Resources|Supervision|Visualization|Writing--review & editing	Funding acquisition	-	Funding acquisition	YES
6471170	30832339	M.E.M.	CRediT	Conceptualization|Funding acquisition|Investigation|Project administration|Resources|Supervision|Visualization|Writing--review & editing	Investigation	Performed the experiments	Investigation	YES
6471170	30832339	M.E.M.	CRediT	Conceptualization|Funding acquisition|Investigation|Project administration|Resources|Supervision|Visualization|Writing--review & editing	Project administration	-	Project administration	YES
6471170	30832339	M.E.M.	CRediT	Conceptualization|Funding acquisition|Investigation|Project administration|Resources|Supervision|Visualization|Writing--review & editing	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6471170	30832339	M.E.M.	CRediT	Conceptualization|Funding acquisition|Investigation|Project administration|Resources|Supervision|Visualization|Writing--review & editing	Supervision	-	Supervision	YES
6471170	30832339	M.E.M.	CRediT	Conceptualization|Funding acquisition|Investigation|Project administration|Resources|Supervision|Visualization|Writing--review & editing	Visualization	Analyzed the data	Visualization	YES
6471170	30832339	M.E.M.	CRediT	Conceptualization|Funding acquisition|Investigation|Project administration|Resources|Supervision|Visualization|Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
5041501	27681232	AK	2	cultivated the fungus and performed genomic & transcription analyses	cultivated the fungus and performed genomic & transcription analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5041501	27681232	CO	2	evaluated the classification and phylogeny of peroxidases & catalases and finalized the manuscript	evaluated the classification and phylogeny of peroxidases & catalases and finalized the manuscript	Wrote the paper	Writing - Review & Editing	YES
5041501	27681232	HT	2	performed the sequencing and assembled the contigs	performed the sequencing and assembled the contigs	Performed the experiments	Investigation	YES
5041501	27681232	KC	2	optimised the isolation of fungal dna and performed genomic & transcription analysis	optimised the isolation of fungal dna and performed genomic & transcription analysis	Performed the experiments	Investigation	YES
5041501	27681232	KL	2	prepared the genomic dna for sequencing and contributed to the discussion	prepared the genomic dna for sequencing and contributed to the discussion	Performed the experiments	Investigation	YES
5041501	27681232	MZ	2	selected the fungus, designed all experiments, performed all molecular phylogeny analyses and wrote the manuscript	selected the fungus, designed all experiments, performed all molecular phylogeny analyses and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4398538	25875816	AL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398538	25875816	AL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398538	25875816	AL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398538	25875816	AQ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398538	25875816	AQ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398538	25875816	AQ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398538	25875816	AQ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398538	25875816	NR	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398538	25875816	NR	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398538	25875816	NR	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398538	25875816	NR	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398538	25875816	SHAC	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398538	25875816	TAT	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4398538	25875816	TAT	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4869608	27212793	All authors	PLoS52	have read, commented, and approved the final version of the paper	have read, commented, and approved the final version of the paper	-	-	NO
4869608	27212793	D.Z.	PLoS52	conceived the idea and designed the experiments|analyzed data|wrote the paper	conceived the idea and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4869608	27212793	D.Z.	PLoS52	conceived the idea and designed the experiments|analyzed data|wrote the paper	analyzed data	Analyzed the data	Formal analysis	YES
4869608	27212793	D.Z.	PLoS52	conceived the idea and designed the experiments|analyzed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4869608	27212793	G.H.	PLoS52	performed the research	performed the research	Performed the experiments	Investigation	YES
4869608	27212793	H.F.	PLoS52	performed the research	performed the research	Performed the experiments	Investigation	YES
4869608	27212793	J.C.	PLoS52	conceived the idea and designed the experiments|performed the research|contributed equally	conceived the idea and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4869608	27212793	J.C.	PLoS52	conceived the idea and designed the experiments|performed the research|contributed equally	performed the research	Performed the experiments	Investigation	YES
4869608	27212793	J.C.	PLoS52	conceived the idea and designed the experiments|performed the research|contributed equally	contributed equally	-	-	NO
4869608	27212793	W.W.	PLoS52	performed the research	performed the research	Performed the experiments	Investigation	YES
4869608	27212793	Y.K.	PLoS52	conceived the idea and designed the experiments|performed the research|analyzed data|wrote the paper|contributed equally	conceived the idea and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4869608	27212793	Y.K.	PLoS52	conceived the idea and designed the experiments|performed the research|analyzed data|wrote the paper|contributed equally	performed the research	Performed the experiments	Investigation	YES
4869608	27212793	Y.K.	PLoS52	conceived the idea and designed the experiments|performed the research|analyzed data|wrote the paper|contributed equally	analyzed data	Analyzed the data	Formal analysis	YES
4869608	27212793	Y.K.	PLoS52	conceived the idea and designed the experiments|performed the research|analyzed data|wrote the paper|contributed equally	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4869608	27212793	Y.K.	PLoS52	conceived the idea and designed the experiments|performed the research|analyzed data|wrote the paper|contributed equally	contributed equally	-	-	NO
3687073	23782482	All authors	2	contributed to the content of the manuscript and all authors have read and approved the final version	contributed to the content of the manuscript and all authors have read and approved the final version	-	-	NO
6345259	30687846	C.H.L.	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
6345259	30687846	Contributions	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6345259	30687846	G.I.	PLoS52	conceived and designed the experiments|analyzed the data and wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6345259	30687846	G.I.	PLoS52	conceived and designed the experiments|analyzed the data and wrote the paper	analyzed the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6345259	30687846	N.G.	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
6345259	30687846	S.P.	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data and wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6345259	30687846	S.P.	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data and wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
6345259	30687846	S.P.	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data and wrote the paper	analyzed the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6471177	30897775	K.L.	CRediT	Conceptualization|resources|writing--original draft preparation|writing--review and editing|supervision	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6471177	30897775	K.L.	CRediT	Conceptualization|resources|writing--original draft preparation|writing--review and editing|supervision	resources	Contributed reagents/materials/analysis tools	Resources	YES
6471177	30897775	K.L.	CRediT	Conceptualization|resources|writing--original draft preparation|writing--review and editing|supervision	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6471177	30897775	K.L.	CRediT	Conceptualization|resources|writing--original draft preparation|writing--review and editing|supervision	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6471177	30897775	K.L.	CRediT	Conceptualization|resources|writing--original draft preparation|writing--review and editing|supervision	supervision	-	Supervision	YES
6471177	30897775	Q.L.	CRediT	resources	resources	Contributed reagents/materials/analysis tools	Resources	YES
6471177	30897775	S.Y.H.	CRediT	investigation|writing--original draft preparation|writing--review and editing	investigation	Performed the experiments	Investigation	YES
6471177	30897775	S.Y.H.	CRediT	investigation|writing--original draft preparation|writing--review and editing	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6471177	30897775	S.Y.H.	CRediT	investigation|writing--original draft preparation|writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6471177	30897775	Y.H.C.	CRediT	Conceptualization|methodology|writing--original draft preparation|writing--review and editing|supervision	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6471177	30897775	Y.H.C.	CRediT	Conceptualization|methodology|writing--original draft preparation|writing--review and editing|supervision	methodology	Performed the experiments	Methodology	YES
6471177	30897775	Y.H.C.	CRediT	Conceptualization|methodology|writing--original draft preparation|writing--review and editing|supervision	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6471177	30897775	Y.H.C.	CRediT	Conceptualization|methodology|writing--original draft preparation|writing--review and editing|supervision	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6471177	30897775	Y.H.C.	CRediT	Conceptualization|methodology|writing--original draft preparation|writing--review and editing|supervision	supervision	-	Supervision	YES
5447077	28611792	MA	2	designed and planned the experiment	designed and planned the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5447077	28611792	MM	2	assisted in verifying and editing the final version of the manuscript and prepared the manuscript as required by the journal guidelines	assisted in verifying and editing the final version of the manuscript and prepared the manuscript as required by the journal guidelines	Performed the experiments|Wrote the paper	Validation|Writing - Original Draft|Writing - Review & Editing	YES
5447077	28611792	RU	2	helped in reformulating the manuscript and drafted the manuscript more informative	helped in reformulating the manuscript and drafted the manuscript more informative	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5447077	28611792	SS	2	helped in the manuscript writing data evaluation, analysis of results, and resolving critical questions related to the manuscript	helped in the manuscript writing data evaluation, analysis of results, and resolving critical questions related to the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5447077	28611792	VG	2	assisted in manuscript editing, data evaluation	assisted in manuscript editing, data evaluation	Wrote the paper	Writing - Review & Editing	YES
5447077	28611792	VS	2	assisted in some experimental sections and did the computational analysis of the results	assisted in some experimental sections and did the computational analysis of the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5043600	27687780	BL	PLoS52	conceived the project|analyzed the data and contributed to scientific discussions|wrote the paper	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5043600	27687780	BL	PLoS52	conceived the project|analyzed the data and contributed to scientific discussions|wrote the paper	analyzed the data and contributed to scientific discussions	Analyzed the data	Formal analysis	YES
5043600	27687780	BL	PLoS52	conceived the project|analyzed the data and contributed to scientific discussions|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5043600	27687780	DL	PLoS52	developed the rna editing detection pipeline	developed the rna editing detection pipeline	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5043600	27687780	HX	PLoS52	developed the rna editing detection pipeline	developed the rna editing detection pipeline	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5043600	27687780	HY	PLoS52	provided project management	provided project management	-	Project administration	YES
5043600	27687780	KM	PLoS52	analyzed the data and contributed to scientific discussions|wrote the paper	analyzed the data and contributed to scientific discussions	Analyzed the data	Formal analysis	YES
5043600	27687780	KM	PLoS52	analyzed the data and contributed to scientific discussions|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5043600	27687780	KW	PLoS52	provided project management	provided project management	-	Project administration	YES
5043600	27687780	SQ	PLoS52	contributed equally to this work|conceived the project|analyzed the data and contributed to scientific discussions|wrote the paper	contributed equally to this work	-	-	NO
5043600	27687780	SQ	PLoS52	contributed equally to this work|conceived the project|analyzed the data and contributed to scientific discussions|wrote the paper	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5043600	27687780	SQ	PLoS52	contributed equally to this work|conceived the project|analyzed the data and contributed to scientific discussions|wrote the paper	analyzed the data and contributed to scientific discussions	Analyzed the data	Formal analysis	YES
5043600	27687780	SQ	PLoS52	contributed equally to this work|conceived the project|analyzed the data and contributed to scientific discussions|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5043600	27687780	WL	PLoS52	contributed equally to this work|analyzed the data and contributed to scientific discussions	contributed equally to this work	-	-	NO
5043600	27687780	WL	PLoS52	contributed equally to this work|analyzed the data and contributed to scientific discussions	analyzed the data and contributed to scientific discussions	Analyzed the data	Formal analysis	YES
5043600	27687780	XZ	PLoS52	provided project management	provided project management	-	Project administration	YES
5043600	27687780	YB	PLoS52	analyzed the data and contributed to scientific discussions	analyzed the data and contributed to scientific discussions	Analyzed the data	Formal analysis	YES
4398539	25874701	DXY	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398539	25874701	JJL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398539	25874701	JJL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398539	25874701	WL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398539	25874701	WL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398539	25874701	WL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398539	25874701	WL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398539	25874701	XWZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5447082	28611801	The authors	2	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	Performed the experiments	Investigation	YES
4417575	25961048	Hagen Frickmann	2	equally contributed to this work	equally contributed to this work	-	-	NO
4417575	25961048	Ulrike Loderstaedt	2	equally contributed to this work	equally contributed to this work	-	-	NO
5045587	27716057	AG	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5045587	27716057	AP	PLoS5	Conceived and designed the study/experiments	Conceived and designed the study/experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5045587	27716057	BL	PLoS5	Conceived and designed the study/experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the study/experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5045587	27716057	BL	PLoS5	Conceived and designed the study/experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
5045587	27716057	BL	PLoS5	Conceived and designed the study/experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5045587	27716057	BL	PLoS5	Conceived and designed the study/experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5045587	27716057	ETH	PLoS5	Conceived and designed the study/experiments|Wrote the paper	Conceived and designed the study/experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5045587	27716057	ETH	PLoS5	Conceived and designed the study/experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5045587	27716057	JP	PLoS5	Conceived and designed the study/experiments	Conceived and designed the study/experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5045587	27716057	KBR	PLoS5	Conceived and designed the study/experiments	Conceived and designed the study/experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5045587	27716057	LB	PLoS5	Conceived and designed the study/experiments|Performed the experiments|Analyzed the data	Conceived and designed the study/experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5045587	27716057	LB	PLoS5	Conceived and designed the study/experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
5045587	27716057	LB	PLoS5	Conceived and designed the study/experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5045587	27716057	LL	PLoS5	Conceived and designed the study/experiments|Performed the experiments|Analyzed the data	Conceived and designed the study/experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5045587	27716057	LL	PLoS5	Conceived and designed the study/experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
5045587	27716057	LL	PLoS5	Conceived and designed the study/experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5045587	27716057	LLG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5045587	27716057	MK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5045587	27716057	NF	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5045587	27716057	SH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5045587	27716057	TLN	PLoS5	Conceived and designed the study/experiments	Conceived and designed the study/experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5045587	27716057	YVI	PLoS5	Conceived and designed the study/experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the study/experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5045587	27716057	YVI	PLoS5	Conceived and designed the study/experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
5045587	27716057	YVI	PLoS5	Conceived and designed the study/experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5045587	27716057	YVI	PLoS5	Conceived and designed the study/experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3687076	23782484	Both authors	2	contributed to the writing of the manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
3687076	23782484	LMM	2	finalized the draft and all authors approved this version for publication	finalized the draft and all authors approved this version for publication	Wrote the paper	Writing - Original Draft	YES
4398541	25875300	AG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398541	25875300	AG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398541	25875300	AG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398541	25875300	AG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398541	25875300	AG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398541	25875300	IRE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398541	25875300	IRE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4398541	25875300	IRE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4398541	25875300	IRE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398541	25875300	MM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398541	25875300	MM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398541	25875300	MM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398541	25875300	MM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398541	25875300	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398541	25875300	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4398541	25875300	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4398541	25875300	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398541	25875300	RP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398541	25875300	RP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398541	25875300	RP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398541	25875300	RP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398541	25875300	VC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398541	25875300	VC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398541	25875300	VC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398541	25875300	VC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4417578	25961012	Birte Svensson	2	helped write and revise the paper	helped write and revise the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4417578	25961012	Sampo J. Lahtinen	2	helped write and revise the paper	helped write and revise the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4417578	25961012	Susanne Jacobsen	2	helped write and revise the paper	helped write and revise the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5447229	28611799	AK	PLoS52	conceived and designed the experiments|analyzed the data|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5447229	28611799	AK	PLoS52	conceived and designed the experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5447229	28611799	AK	PLoS52	conceived and designed the experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5447229	28611799	I-JL	PLoS52	analyzed the data|contributed reagents/materials/analysis tools	analyzed the data	Analyzed the data	Formal analysis	YES
5447229	28611799	I-JL	PLoS52	analyzed the data|contributed reagents/materials/analysis tools	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5447229	28611799	RS	PLoS52	conceived and designed the experiments|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5447229	28611799	RS	PLoS52	conceived and designed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5447229	28611799	S-MK	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5447229	28611799	SA	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5447229	28611799	SB	PLoS52	conceived and designed the experiments|performed the experiments|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5447229	28611799	SB	PLoS52	conceived and designed the experiments|performed the experiments|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5447229	28611799	SB	PLoS52	conceived and designed the experiments|performed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3687077	23782476	Both authors	2	contributed equally to conceiving, writing and editing of this manuscript	contributed equally to conceiving, writing and editing of this manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
5045590	27716052	LT	2	analyzed rna seq data	analyzed rna seq data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5045590	27716052	LX	2	collected samples|analyzed rna seq data	collected samples	Performed the experiments	Investigation	YES
5045590	27716052	LX	2	collected samples|analyzed rna seq data	analyzed rna seq data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5045590	27716052	TC	2	conceived and designed the experiment	conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5045590	27716052	WY	2	conceived and designed the experiment|collected samples|extracted rna for sequencing|analyzed rna seq data|wrote the manuscript	conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5045590	27716052	WY	2	conceived and designed the experiment|collected samples|extracted rna for sequencing|analyzed rna seq data|wrote the manuscript	collected samples	Performed the experiments	Investigation	YES
5045590	27716052	WY	2	conceived and designed the experiment|collected samples|extracted rna for sequencing|analyzed rna seq data|wrote the manuscript	extracted rna for sequencing	Performed the experiments	Investigation	YES
5045590	27716052	WY	2	conceived and designed the experiment|collected samples|extracted rna for sequencing|analyzed rna seq data|wrote the manuscript	analyzed rna seq data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5045590	27716052	WY	2	conceived and designed the experiment|collected samples|extracted rna for sequencing|analyzed rna seq data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5045590	27716052	ZW	2	analyzed rna seq data	analyzed rna seq data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6471246	30893852	B.H.	CRediT	Conceptualization|Wring|Editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6471246	30893852	B.H.	CRediT	Conceptualization|Wring|Editing	Wring	-	-	NO
6471246	30893852	B.H.	CRediT	Conceptualization|Wring|Editing	Editing	Wrote the paper	Writing - Review & Editing	YES
6471246	30893852	H.-J.C.	CRediT	Conceptualization|Wring|Editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6471246	30893852	H.-J.C.	CRediT	Conceptualization|Wring|Editing	Wring	-	-	NO
6471246	30893852	H.-J.C.	CRediT	Conceptualization|Wring|Editing	Editing	Wrote the paper	Writing - Review & Editing	YES
6471246	30893852	X.L.	CRediT	Wring	Wring	-	-	NO
4398542	25875774	GHK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398542	25875774	GHK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398542	25875774	GHK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398542	25875774	GHK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398542	25875774	GL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4398542	25875774	GL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398542	25875774	JMB	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4398542	25875774	JMB	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398542	25875774	NYC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4398542	25875774	NYC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398542	25875774	YK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398542	25875774	YK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398542	25875774	YK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398542	25875774	YK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398542	25875774	YK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5447670	28611804	JC	PLoS52	improved the language	improved the language	-	-	NO
5447670	28611804	JY	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5447670	28611804	QT	PLoS52	improved the language|analyzed the data	improved the language	-	-	NO
5447670	28611804	QT	PLoS52	improved the language|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5447670	28611804	XJ	PLoS52	constructed the plant transformation vector and performed the rice transformation	constructed the plant transformation vector and performed the rice transformation	Performed the experiments	Investigation	YES
5447670	28611804	XL	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5447670	28611804	XiaZ	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5447670	28611804	XinZ	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5447670	28611804	YD	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5045647	27716062	AC	7	Participated in the analysis of gbs data and advice in installation of uneak pipeline in the server	Participated in the analysis of gbs data and advice in installation of uneak pipeline in the server	Analyzed the data	Formal analysis	YES
5045647	27716062	AD	7	Participated in the study design	Participated in the study design	Conceived and designed the experiments	Methodology	YES
5045647	27716062	AN	7	Did the sampling and speciation of the midges	Did the sampling and speciation of the midges	Performed the experiments	Investigation	YES
5045647	27716062	CJ	7	Participated in the analysis of gbs data	Participated in the analysis of gbs data	Analyzed the data	Formal analysis	YES
5045647	27716062	GB	7	Did the sampling and speciation of the midges	Did the sampling and speciation of the midges	Performed the experiments	Investigation	YES
5045647	27716062	JBD	7	Involved in the study design, participated in the writing of the paper	Involved in the study design, participated in the writing of the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5045647	27716062	JO	7	Participated in the experimental design of the gbs experiment and in the installation of uneak pipeline at ILRIs server	Participated in the experimental design of the gbs experiment and in the installation of uneak pipeline at ILRIs server	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5045647	27716062	MGO	7	Designed, conducted the experiments, analysed results and drafted the paper	Designed, conducted the experiments, analysed results and drafted the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5045647	27716062	NCA	7	Participated in the experimental design of the gbs experiment and advice on experimental plans	Participated in the experimental design of the gbs experiment and advice on experimental plans	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5045647	27716062	PJW	7	Involved in the study design, participated in the writing of the paper	Involved in the study design, participated in the writing of the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5045647	27716062	SK	7	Participated in the study design	Participated in the study design	Conceived and designed the experiments	Methodology	YES
3687078	23782478	CAM	2	have made substantial contributions to the review process and analyses of studies	have made substantial contributions to the review process and analyses of studies	Analyzed the data	Formal analysis	YES
3687078	23782478	KMM	2	have made substantial contributions to the review process and analyses of studies	have made substantial contributions to the review process and analyses of studies	Analyzed the data	Formal analysis	YES
4398543	25875837	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398543	25875837	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398543	25875837	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398543	25875837	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398543	25875837	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398543	25875837	AS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398543	25875837	AS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398543	25875837	AS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398543	25875837	FY	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4398543	25875837	FY	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4398543	25875837	JS	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4398543	25875837	KN	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398543	25875837	MM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398543	25875837	MM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398543	25875837	MM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398543	25875837	MM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398543	25875837	MM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398543	25875837	RO	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398543	25875837	ST	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398543	25875837	ST	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398543	25875837	TK	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398543	25875837	TK	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398543	25875837	YM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
6471263	30884782	A.W.Y.L.	CRediT	Conceptualization|Writing--original draft preparation|Writing--review & editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6471263	30884782	A.W.Y.L.	CRediT	Conceptualization|Writing--original draft preparation|Writing--review & editing	Writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6471263	30884782	A.W.Y.L.	CRediT	Conceptualization|Writing--original draft preparation|Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6471263	30884782	C.A.	CRediT	Writing--original draft preparation|Writing--review & editing	Writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6471263	30884782	C.A.	CRediT	Writing--original draft preparation|Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6471263	30884782	L.C.W.	CRediT	Writing--original draft preparation|Writing--review & editing	Writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6471263	30884782	L.C.W.	CRediT	Writing--original draft preparation|Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6471263	30884782	M.B.B.	CRediT	Conceptualization|Writing--review & editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6471263	30884782	M.B.B.	CRediT	Conceptualization|Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6471263	30884782	U.V.M.	CRediT	Writing--original draft preparation|Writing--review & editing	Writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6471263	30884782	U.V.M.	CRediT	Writing--original draft preparation|Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
5045658	27716053	BFP	2	designed and completed wet lab experiments, performed bioinformatic analyses, and wrote and revised the manuscript|have read and approve the final manuscript	designed and completed wet lab experiments, performed bioinformatic analyses, and wrote and revised the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5045658	27716053	BFP	2	designed and completed wet lab experiments, performed bioinformatic analyses, and wrote and revised the manuscript|have read and approve the final manuscript	have read and approve the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5045658	27716053	MES	2	designed experiments, provided input on analyses, and wrote and revised the manuscript|have read and approve the final manuscript	designed experiments, provided input on analyses, and wrote and revised the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5045658	27716053	MES	2	designed experiments, provided input on analyses, and wrote and revised the manuscript|have read and approve the final manuscript	have read and approve the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5447673	28611797	AA	7	participated in experiment setup and measurements	participated in experiment setup and measurements	Performed the experiments	Investigation	YES
5447673	28611797	AD	7	participated in the data analysis	participated in the data analysis	Analyzed the data	Formal analysis	YES
5447673	28611797	FF	7	designed and supervised the research and contributed to the writing of the manuscript	designed and supervised the research and contributed to the writing of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Original Draft	YES
5447673	28611797	RK	7	participated in experiment setup and measurements	participated in experiment setup and measurements	Performed the experiments	Investigation	YES
5447673	28611797	SJ	7	participated in the design and editing of the manuscript	participated in the design and editing of the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Review & Editing	YES
5447673	28611797	SK	7	Designed the study, performed data analysis, and wrote the manuscript	Designed the study, performed data analysis, and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5447673	28611797	WV	7	participated in the design and editing of the manuscript	participated in the design and editing of the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Review & Editing	YES
4398544	25875024	GP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Assisted surgery and testing|Contributed to final version	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398544	25875024	GP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Assisted surgery and testing|Contributed to final version	Performed the experiments	Performed the experiments	Investigation	YES
4398544	25875024	GP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Assisted surgery and testing|Contributed to final version	Analyzed the data	Analyzed the data	Formal analysis	YES
4398544	25875024	GP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Assisted surgery and testing|Contributed to final version	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398544	25875024	GP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Assisted surgery and testing|Contributed to final version	Assisted surgery and testing	Performed the experiments	Investigation	YES
4398544	25875024	GP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Assisted surgery and testing|Contributed to final version	Contributed to final version	-	-	NO
4398544	25875024	SJR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Surgery and testing|Wrote first draft|Contributed to final version	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398544	25875024	SJR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Surgery and testing|Wrote first draft|Contributed to final version	Performed the experiments	Performed the experiments	Investigation	YES
4398544	25875024	SJR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Surgery and testing|Wrote first draft|Contributed to final version	Analyzed the data	Analyzed the data	Formal analysis	YES
4398544	25875024	SJR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Surgery and testing|Wrote first draft|Contributed to final version	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398544	25875024	SJR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Surgery and testing|Wrote first draft|Contributed to final version	Surgery and testing	Performed the experiments	Investigation	YES
4398544	25875024	SJR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Surgery and testing|Wrote first draft|Contributed to final version	Wrote first draft	Wrote the paper	Writing - Original Draft	YES
4398544	25875024	SJR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Surgery and testing|Wrote first draft|Contributed to final version	Contributed to final version	-	-	NO
3687079	23782483	HCW	2	wrote the initial draft and undertook the literature search	wrote the initial draft and undertook the literature search	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3687079	23782483	MFC	2	contributed to the literature search and co-wrote this article	contributed to the literature search and co-wrote this article	Wrote the paper	Formal analysis|Writing - Original Draft	YES
3687079	23782483	RPG	2	co-wrote this article and gave important advice	co-wrote this article and gave important advice	Wrote the paper	Writing - Original Draft	YES
6471271	30884755	A.G.-A.	2	contributed to the writing of this manuscript and the analyses and interpretation of the data	contributed to the writing of this manuscript and the analyses and interpretation of the data	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
6471271	30884755	A.R.-P.	2	contributed to the writing of this manuscript and the analyses and interpretation of the data	contributed to the writing of this manuscript and the analyses and interpretation of the data	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
6471271	30884755	B.H.	2	contributed to the writing of this manuscript and the analyses and interpretation of the data	contributed to the writing of this manuscript and the analyses and interpretation of the data	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
6471271	30884755	D.M.	2	contributed to the writing of this manuscript and the analyses and interpretation of the data	contributed to the writing of this manuscript and the analyses and interpretation of the data	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
6471271	30884755	G.E.A.	2	designed and experimentally conducted the in vitro experiments	designed and experimentally conducted the in vitro experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6471271	30884755	G.K.	2	designed and experimentally conducted the in vitro experiments	designed and experimentally conducted the in vitro experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6471271	30884755	G.L.A.	2	designed and experimentally conducted the in vitro experiments	designed and experimentally conducted the in vitro experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6471271	30884755	I.G.-A.	2	designed and experimentally conducted the in vitro experiments	designed and experimentally conducted the in vitro experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6471271	30884755	J.A.-G.	2	designed and experimentally conducted the in vitro experiments	designed and experimentally conducted the in vitro experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6471271	30884755	M.B.	2	designed and experimentally conducted the in vitro experiments	designed and experimentally conducted the in vitro experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6471271	30884755	N.R.-H.	2	designed and experimentally conducted the in vitro experiments	designed and experimentally conducted the in vitro experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6471271	30884755	Y.T.	2	contributed to the writing of this manuscript and the analyses and interpretation of the data	contributed to the writing of this manuscript and the analyses and interpretation of the data	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
5045660	27716056	JX	PLoS52	performed the data analysis and interpreted the results	performed the data analysis and interpreted the results	Analyzed the data	Formal analysis	YES
5045660	27716056	LW	PLoS52	performed the chip-seq experiments	performed the chip-seq experiments	Performed the experiments	Investigation	YES
5045660	27716056	QY	PLoS52	performed the data analysis and interpreted the results	performed the data analysis and interpreted the results	Analyzed the data	Formal analysis	YES
5045660	27716056	WZ	PLoS52	conceived and designed the study|performed the data analysis and interpreted the results|wrote the paper	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5045660	27716056	WZ	PLoS52	conceived and designed the study|performed the data analysis and interpreted the results|wrote the paper	performed the data analysis and interpreted the results	Analyzed the data	Formal analysis	YES
5045660	27716056	WZ	PLoS52	conceived and designed the study|performed the data analysis and interpreted the results|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5045660	27716056	XMW	PLoS52	performed the chip-seq experiments	performed the chip-seq experiments	Performed the experiments	Investigation	YES
5045660	27716056	XP	PLoS52	performed the chip-seq experiments	performed the chip-seq experiments	Performed the experiments	Investigation	YES
5045660	27716056	XW	PLoS52	supervised the experiments	supervised the experiments	-	Supervision	YES
5045660	27716056	YF	PLoS52	performed the data analysis and interpreted the results	performed the data analysis and interpreted the results	Analyzed the data	Formal analysis	YES
5045660	27716056	YW	PLoS52	performed the data analysis and interpreted the results	performed the data analysis and interpreted the results	Analyzed the data	Formal analysis	YES
5045660	27716056	ZS	PLoS52	performed the data analysis and interpreted the results	performed the data analysis and interpreted the results	Analyzed the data	Formal analysis	YES
5447678	28611795	DI	2	contributed to a general revision of the manuscript	contributed to a general revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5447678	28611795	JM-A	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4398546	25875359	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398546	25875359	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398546	25875359	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398546	25875359	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398546	25875359	FS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398546	25875359	FS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398546	25875359	FS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398546	25875359	FS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398546	25875359	GV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398546	25875359	GV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398546	25875359	GV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398546	25875359	GV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398546	25875359	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398546	25875359	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398546	25875359	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398546	25875359	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6471285	30897776	D.-J.J.	PLoS52	conceived of and designed the experiments|analyzed the data|wrote the paper	conceived of and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6471285	30897776	D.-J.J.	PLoS52	conceived of and designed the experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
6471285	30897776	D.-J.J.	PLoS52	conceived of and designed the experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6471285	30897776	D.Y.K.	PLoS52	contributed reagents/materials|wrote the paper	contributed reagents/materials	Contributed reagents/materials/analysis tools	Resources	YES
6471285	30897776	D.Y.K.	PLoS52	contributed reagents/materials|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6471285	30897776	E.-J.H.	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
6471285	30897776	H.-J.M.	PLoS52	conceived of and designed the experiments|analyzed the data|wrote the paper	conceived of and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6471285	30897776	H.-J.M.	PLoS52	conceived of and designed the experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
6471285	30897776	H.-J.M.	PLoS52	conceived of and designed the experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6471285	30897776	H.J.K.	PLoS52	performed the experiments|analyzed the data|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
6471285	30897776	H.J.K.	PLoS52	performed the experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
6471285	30897776	H.J.K.	PLoS52	performed the experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6471285	30897776	J.-M.B.	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
6471285	30897776	K.H.C.	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6471285	30897776	S.H.P.	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
6471285	30897776	S.K.	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
6471285	30897776	S.Y.P.	PLoS52	analyzed the data|contributed reagents/materials	analyzed the data	Analyzed the data	Formal analysis	YES
6471285	30897776	S.Y.P.	PLoS52	analyzed the data|contributed reagents/materials	contributed reagents/materials	Contributed reagents/materials/analysis tools	Resources	YES
6471285	30897776	Y.-H.H.	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
6471285	30897776	Y.-H.K.	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5447703	28611819	GU	1	Acquisition of data|Analysis and interpretation of data|Drafting of manuscript	Acquisition of data	Performed the experiments	Investigation	YES
5447703	28611819	GU	1	Acquisition of data|Analysis and interpretation of data|Drafting of manuscript	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
5447703	28611819	GU	1	Acquisition of data|Analysis and interpretation of data|Drafting of manuscript	Drafting of manuscript	Wrote the paper	Writing - Original Draft	YES
5447703	28611819	SR	1	Study conception and design|Drafting of manuscript|Critical revision	Study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5447703	28611819	SR	1	Study conception and design|Drafting of manuscript|Critical revision	Drafting of manuscript	Wrote the paper	Writing - Original Draft	YES
5447703	28611819	SR	1	Study conception and design|Drafting of manuscript|Critical revision	Critical revision	Wrote the paper	Writing - Review & Editing	YES
5447703	28611819	TH	1	Study conception and design|Acquisition of data|Analysis and interpretation of data|Drafting of manuscript	Study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5447703	28611819	TH	1	Study conception and design|Acquisition of data|Analysis and interpretation of data|Drafting of manuscript	Acquisition of data	Performed the experiments	Investigation	YES
5447703	28611819	TH	1	Study conception and design|Acquisition of data|Analysis and interpretation of data|Drafting of manuscript	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
5447703	28611819	TH	1	Study conception and design|Acquisition of data|Analysis and interpretation of data|Drafting of manuscript	Drafting of manuscript	Wrote the paper	Writing - Original Draft	YES
3687339	23782479	All authors	2	have contributed equally to the work	have contributed equally to the work	-	-	NO
4398547	25876071	AJ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398547	25876071	AJ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398547	25876071	BGF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398547	25876071	BGF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398547	25876071	BGF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398547	25876071	BGF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398547	25876071	HY	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398547	25876071	HY	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398547	25876071	HY	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398547	25876071	HY	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398547	25876071	JE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398547	25876071	JE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398547	25876071	JE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398547	25876071	JE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398547	25876071	JE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398547	25876071	JFG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398547	25876071	JFG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398547	25876071	JFG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398547	25876071	JFG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398547	25876071	JN	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398547	25876071	JN	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398547	25876071	MAM	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398547	25876071	MCP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398547	25876071	MCP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398547	25876071	MCP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398547	25876071	PN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398547	25876071	PN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398547	25876071	PN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398547	25876071	PN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398547	25876071	RFS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398547	25876071	TA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398547	25876071	TA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398547	25876071	TA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398547	25876071	TA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398547	25876071	XL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398547	25876071	XL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398547	25876071	XL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398547	25876071	XL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5050567	27716061	All authors	2	reviewed and contributed to draft the manuscript	reviewed and contributed to draft the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5050567	27716061	FL	2	conducted the experimental work and performed data analysis	conducted the experimental work and performed data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5050567	27716061	PP	2	supervised the experimental work and participated in data interpretation	supervised the experimental work and participated in data interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Supervision	YES
5050567	27716061	SH	2	supervised the experimental work and participated in data interpretation	supervised the experimental work and participated in data interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Supervision	YES
6471382	30897794	A.H.	2	prepared and characterized the imq inclusion complexes	prepared and characterized the imq inclusion complexes	Performed the experiments	Investigation	YES
6471382	30897794	C.B.	2	designed the experiments and gave the intellectual rationale to the work	designed the experiments and gave the intellectual rationale to the work	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6471382	30897794	C.C.	2	designed the experiments and gave the intellectual rationale to the work	designed the experiments and gave the intellectual rationale to the work	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6471382	30897794	D.A.	2	performed the biological experiments	performed the biological experiments	Performed the experiments	Investigation	YES
6471382	30897794	F.C.	2	synthetized the nanosponges	synthetized the nanosponges	-	-	NO
6471382	30897794	F.T.	2	synthetized the nanosponges	synthetized the nanosponges	-	-	NO
6471382	30897794	L.J.	2	prepared and characterized the imq inclusion complexes	prepared and characterized the imq inclusion complexes	Performed the experiments	Investigation	YES
6471382	30897794	M.A.	2	formulated and in vitro characterized the nanosponge nanoformulations	formulated and in vitro characterized the nanosponge nanoformulations	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
6471382	30897794	M.F.	2	performed the biological experiments	performed the biological experiments	Performed the experiments	Investigation	YES
6471382	30897794	R.C.	2	designed the experiments and gave the intellectual rationale to the work	designed the experiments and gave the intellectual rationale to the work	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6471382	30897794	S.S.	2	performed the biological experiments	performed the biological experiments	Performed the experiments	Investigation	YES
6471382	30897794	T.M.	2	performed the biological experiments	performed the biological experiments	Performed the experiments	Investigation	YES
5447709	28611810	FC	2	collected and analyzed the data|wrote, revised, and approved the manuscript	collected and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5447709	28611810	FC	2	collected and analyzed the data|wrote, revised, and approved the manuscript	wrote, revised, and approved the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5447709	28611810	LZ	2	designed the research|collected and analyzed the data|wrote, revised, and approved the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
5447709	28611810	LZ	2	designed the research|collected and analyzed the data|wrote, revised, and approved the manuscript	collected and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5447709	28611810	LZ	2	designed the research|collected and analyzed the data|wrote, revised, and approved the manuscript	wrote, revised, and approved the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5447709	28611810	XL	2	wrote, revised, and approved the manuscript	wrote, revised, and approved the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5447709	28611810	XZ	2	wrote, revised, and approved the manuscript	wrote, revised, and approved the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4417590	25961011	Siew Ching Ngai	2	are equal contributors	are equal contributors	-	-	NO
4417590	25961011	Syahril Abdullah	2	are equal contributors	are equal contributors	-	-	NO
3691550	23782481	ARE	2	participated in the writing of the manuscript	participated in the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
3691550	23782481	GAM	2	participated in the writing of the manuscript	participated in the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
3691550	23782481	LBM	2	participated in the writing of the manuscript	participated in the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
3691550	23782481	PM	2	participated in the writing of the manuscript	participated in the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
6471415	30889846	E.A.-P.	CRediT	methodology|data curation|writing--review and editing	methodology	Performed the experiments	Methodology	YES
6471415	30889846	E.A.-P.	CRediT	methodology|data curation|writing--review and editing	data curation	Analyzed the data	Data curation	YES
6471415	30889846	E.A.-P.	CRediT	methodology|data curation|writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6471415	30889846	E.O.	CRediT	conceptualization|methodology|writing--original draft preparation|funding acquisition	conceptualization	Conceived and designed the experiments	Conceptualization	YES
6471415	30889846	E.O.	CRediT	conceptualization|methodology|writing--original draft preparation|funding acquisition	methodology	Performed the experiments	Methodology	YES
6471415	30889846	E.O.	CRediT	conceptualization|methodology|writing--original draft preparation|funding acquisition	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6471415	30889846	E.O.	CRediT	conceptualization|methodology|writing--original draft preparation|funding acquisition	funding acquisition	-	Funding acquisition	YES
6471415	30889846	L.N.	CRediT	methodology	methodology	Performed the experiments	Methodology	YES
6471415	30889846	T.O.	CRediT	methodology|data curation|writing--review and editing	methodology	Performed the experiments	Methodology	YES
6471415	30889846	T.O.	CRediT	methodology|data curation|writing--review and editing	data curation	Analyzed the data	Data curation	YES
6471415	30889846	T.O.	CRediT	methodology|data curation|writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6471415	30889846	T.S.-F.	CRediT	methodology|data curation|writing--review and editing	methodology	Performed the experiments	Methodology	YES
6471415	30889846	T.S.-F.	CRediT	methodology|data curation|writing--review and editing	data curation	Analyzed the data	Data curation	YES
6471415	30889846	T.S.-F.	CRediT	methodology|data curation|writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
4398548	25875943	CH	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398548	25875943	CH	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398548	25875943	CH	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398548	25875943	CH	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398548	25875943	CL	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398548	25875943	CL	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398548	25875943	CL	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398548	25875943	CL	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398548	25875943	DI	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398548	25875943	DI	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398548	25875943	HT	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398548	25875943	HT	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398548	25875943	KM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398548	25875943	KM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398548	25875943	KM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398548	25875943	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398548	25875943	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398548	25875943	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398548	25875943	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398548	25875943	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5050613	27716126	CP	2	carried out the field phenotyping, multivariate and bioinformatics analysis|carried out enzyme assay work|drafted the manuscript	carried out the field phenotyping, multivariate and bioinformatics analysis	Performed the experiments	Formal analysis|Investigation	YES
5050613	27716126	CP	2	carried out the field phenotyping, multivariate and bioinformatics analysis|carried out enzyme assay work|drafted the manuscript	carried out enzyme assay work	Performed the experiments	Investigation	YES
5050613	27716126	CP	2	carried out the field phenotyping, multivariate and bioinformatics analysis|carried out enzyme assay work|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5050613	27716126	NKS	2	edited and approved the manuscript and supervised the work	edited and approved the manuscript and supervised the work	Wrote the paper	Supervision|Writing - Review & Editing	YES
5050613	27716126	PKS	2	carried out enzyme assay work	carried out enzyme assay work	Performed the experiments	Investigation	YES
5050613	27716126	SVAM	2	conceived the experiment, compiled and interpreted the results and coordinated the entire work|drafted the manuscript	conceived the experiment, compiled and interpreted the results and coordinated the entire work	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation|Project administration	YES
5050613	27716126	SVAM	2	conceived the experiment, compiled and interpreted the results and coordinated the entire work|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5050613	27716126	TM	2	developed the mapping population and guided phenotyping under drought	developed the mapping population and guided phenotyping under drought	Performed the experiments	Investigation|Supervision	YES
5447715	28611815	All authors	PLoS52	contributed substantially to revisions|gave final approval for publication	contributed substantially to revisions	Wrote the paper	Writing - Review & Editing	YES
5447715	28611815	All authors	PLoS52	contributed substantially to revisions|gave final approval for publication	gave final approval for publication	-	-	NO
5447715	28611815	KV	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5447715	28611815	PK	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5447715	28611815	XL	PLoS52	performed the experiments and analyzed the data and wrote the first draft of the manuscript	performed the experiments and analyzed the data and wrote the first draft of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3356720	22645447	N. Sugimoto	2	contributed equally to this work	contributed equally to this work	-	-	NO
3356720	22645447	T. Saito	2	contributed equally to this work	contributed equally to this work	-	-	NO
5024651	27656042	A.A.-S.	2	contributed equally	contributed equally	-	-	NO
5024651	27656042	D.M.	2	contributed equally	contributed equally	-	-	NO
3699697	23819908	All authors	2	contributed to revising and commenting on subsequent drafts, and approved the final manuscript	contributed to revising and commenting on subsequent drafts, and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3699697	23819908	PJE	2	wrote the first draft	wrote the first draft	Wrote the paper	Writing - Original Draft	YES
6471433	30934537	A.G.	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
6471433	30934537	A.K.	CRediT	writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6471433	30934537	A.L.	CRediT	Investigation|writing--original draft	Investigation	Performed the experiments	Investigation	YES
6471433	30934537	A.L.	CRediT	Investigation|writing--original draft	writing--original draft	Wrote the paper	Writing - Original Draft	YES
6471433	30934537	E.C.	CRediT	writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6471433	30934537	E.U.	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
6471433	30934537	M.B.-S.	CRediT	writing--original draft	writing--original draft	Wrote the paper	Writing - Original Draft	YES
6471433	30934537	P.V.	CRediT	writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6471433	30934537	S.B.	CRediT	writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
4398549	25875374	GNK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398549	25875374	GNK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398549	25875374	GNK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398549	25875374	GNK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398549	25875374	HZ	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398549	25875374	HZ	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398549	25875374	JF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398549	25875374	JF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398549	25875374	JF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398549	25875374	JF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398549	25875374	JLJ	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398549	25875374	JLJ	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398549	25875374	LR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Revised the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398549	25875374	LR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Revised the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4398549	25875374	LR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Revised the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398549	25875374	LR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Revised the manuscript	Revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4398549	25875374	RT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398549	25875374	RT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398549	25875374	RT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398549	25875374	RT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5050639	27716058	AAFG	PLoS52	designed the hypothesis, methodology and conducted statistical analysis	designed the hypothesis, methodology and conducted statistical analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5050639	27716058	AGR	PLoS52	designed the hypothesis, methodology and conducted statistical analysis|wrote the paper	designed the hypothesis, methodology and conducted statistical analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5050639	27716058	AGR	PLoS52	designed the hypothesis, methodology and conducted statistical analysis|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5050639	27716058	AJC	PLoS52	was in charge of the barley project	was in charge of the barley project	-	-	NO
5050639	27716058	AdP	PLoS52	created the wheat project|conducted phenotyping in wheat	created the wheat project	-	-	NO
5050639	27716058	AdP	PLoS52	created the wheat project|conducted phenotyping in wheat	conducted phenotyping in wheat	Performed the experiments	Investigation	YES
5050639	27716058	BL	PLoS52	conducted the genotyping in wheat|wrote the paper	conducted the genotyping in wheat	Performed the experiments	Investigation	YES
5050639	27716058	BL	PLoS52	conducted the genotyping in wheat|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5050639	27716058	IM	PLoS52	created the wheat project|conducted phenotyping in wheat	created the wheat project	-	-	NO
5050639	27716058	IM	PLoS52	created the wheat project|conducted phenotyping in wheat	conducted phenotyping in wheat	Performed the experiments	Investigation	YES
5050639	27716058	JvZ	PLoS52	created the wheat project|conducted the genotyping in wheat	created the wheat project	-	-	NO
5050639	27716058	JvZ	PLoS52	created the wheat project|conducted the genotyping in wheat	conducted the genotyping in wheat	Performed the experiments	Investigation	YES
5050639	27716058	LG	PLoS52	designed the hypothesis, methodology and conducted statistical analysis|wrote the paper	designed the hypothesis, methodology and conducted statistical analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5050639	27716058	LG	PLoS52	designed the hypothesis, methodology and conducted statistical analysis|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5050639	27716058	MC	PLoS52	created the wheat project	created the wheat project	-	-	NO
5050639	27716058	MM	PLoS52	designed the hypothesis, methodology and conducted statistical analysis	designed the hypothesis, methodology and conducted statistical analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5050639	27716058	MQ	PLoS52	created the wheat project	created the wheat project	-	-	NO
5050639	27716058	SB	PLoS52	designed the hypothesis, methodology and conducted statistical analysis|wrote the paper	designed the hypothesis, methodology and conducted statistical analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5050639	27716058	SB	PLoS52	designed the hypothesis, methodology and conducted statistical analysis|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5447739	28611803	CD	PLoS5	Provided good advice	Provided good advice	-	-	NO
5447739	28611803	EC	PLoS5	Collected samples	Collected samples	Performed the experiments	Investigation	YES
5447739	28611803	FW	PLoS5	Collected samples	Collected samples	Performed the experiments	Investigation	YES
5447739	28611803	GL	PLoS5	Conceived and designed the experiments|Analyzed the data|Revised the manuscript and gave final approval of the version to be published	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5447739	28611803	GL	PLoS5	Conceived and designed the experiments|Analyzed the data|Revised the manuscript and gave final approval of the version to be published	Analyzed the data	Analyzed the data	Formal analysis	YES
5447739	28611803	GL	PLoS5	Conceived and designed the experiments|Analyzed the data|Revised the manuscript and gave final approval of the version to be published	Revised the manuscript and gave final approval of the version to be published	Wrote the paper	Writing - Review & Editing	YES
5447739	28611803	JZ	PLoS5	Performed the experiments|Collected samples|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
5447739	28611803	JZ	PLoS5	Performed the experiments|Collected samples|Analyzed the data	Collected samples	Performed the experiments	Investigation	YES
5447739	28611803	JZ	PLoS5	Performed the experiments|Collected samples|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5447739	28611803	LC	PLoS5	Provided good advice	Provided good advice	-	-	NO
5447739	28611803	LW	PLoS5	Conceived and designed the experiments|Performed the experiments|Collected samples|Analyzed the data|Drafted the manuscript|Revised the manuscript and gave final approval of the version to be published	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5447739	28611803	LW	PLoS5	Conceived and designed the experiments|Performed the experiments|Collected samples|Analyzed the data|Drafted the manuscript|Revised the manuscript and gave final approval of the version to be published	Performed the experiments	Performed the experiments	Investigation	YES
5447739	28611803	LW	PLoS5	Conceived and designed the experiments|Performed the experiments|Collected samples|Analyzed the data|Drafted the manuscript|Revised the manuscript and gave final approval of the version to be published	Collected samples	Performed the experiments	Investigation	YES
5447739	28611803	LW	PLoS5	Conceived and designed the experiments|Performed the experiments|Collected samples|Analyzed the data|Drafted the manuscript|Revised the manuscript and gave final approval of the version to be published	Analyzed the data	Analyzed the data	Formal analysis	YES
5447739	28611803	LW	PLoS5	Conceived and designed the experiments|Performed the experiments|Collected samples|Analyzed the data|Drafted the manuscript|Revised the manuscript and gave final approval of the version to be published	Drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5447739	28611803	LW	PLoS5	Conceived and designed the experiments|Performed the experiments|Collected samples|Analyzed the data|Drafted the manuscript|Revised the manuscript and gave final approval of the version to be published	Revised the manuscript and gave final approval of the version to be published	Wrote the paper	Writing - Review & Editing	YES
5447739	28611803	ST	PLoS5	Provided good advice	Provided good advice	-	-	NO
5447739	28611803	SW	PLoS5	Provided good advice	Provided good advice	-	-	NO
5447739	28611803	WZ	PLoS5	Performed the experiments|Collected samples|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
5447739	28611803	WZ	PLoS5	Performed the experiments|Collected samples|Analyzed the data	Collected samples	Performed the experiments	Investigation	YES
5447739	28611803	WZ	PLoS5	Performed the experiments|Collected samples|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5447739	28611803	YD	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5447739	28611803	ZL	PLoS5	Provided good advice	Provided good advice	-	-	NO
6471441	30893873	A.G.	2	performed the in vitro characterization studies	performed the in vitro characterization studies	Performed the experiments	Investigation	YES
6471441	30893873	All authors	2	contributed for the manuscript preparation	contributed for the manuscript preparation	Wrote the paper	Writing - Original Draft	YES
6471441	30893873	C.C.	2	prepared the formulations and performed the optimization and stability studies	prepared the formulations and performed the optimization and stability studies	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
6471441	30893873	H.M.R.	2	designed and supervised the experiments	designed and supervised the experiments	Conceived and designed the experiments	Methodology|Supervision	YES
6471441	30893873	J.M.	2	designed and supervised the experiments	designed and supervised the experiments	Conceived and designed the experiments	Methodology|Supervision	YES
6471441	30893873	L.M.G.	2	performed the in vitro characterization studies	performed the in vitro characterization studies	Performed the experiments	Investigation	YES
6471441	30893873	P.P.	2	performed the in vivo studies	performed the in vivo studies	Performed the experiments	Investigation	YES
4398550	25875173	AA	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4398550	25875173	AC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398550	25875173	CS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398550	25875173	ED	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398550	25875173	ED	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398550	25875173	FHM	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4398550	25875173	IC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398550	25875173	LC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4398550	25875173	LC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398550	25875173	M. Mistrangelo	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4398550	25875173	M. Morino	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398550	25875173	MP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398550	25875173	MP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398550	25875173	MR	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398550	25875173	MR	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398550	25875173	PC	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398550	25875173	PC	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398550	25875173	PR	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398550	25875173	R. Senetta	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398550	25875173	R. Senetta	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398550	25875173	R. Senetta	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398550	25875173	R. Spadi	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398550	25875173	UR	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398550	25875173	UR	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5089058	27818575	A.J.M.	2	equally contributed to this work	equally contributed to this work	-	-	NO
5089058	27818575	C.G.	2	equally contributed to this work	equally contributed to this work	-	-	NO
5089058	27818575	SS	2	equally contributed to this work	equally contributed to this work	-	-	NO
5050705	27716060	FJ	2	carried out whole-cell recordings	carried out whole-cell recordings	Performed the experiments	Investigation	YES
5050705	27716060	MEA	2	setup and provided expertise in mea recordings	setup and provided expertise in mea recordings	-	-	NO
5050705	27716060	MF	2	analysed data|wrote the manuscript	analysed data	Analyzed the data	Formal analysis	YES
5050705	27716060	MF	2	analysed data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5050705	27716060	MG	2	performed all biochemical and mea experiments|analysed data	performed all biochemical and mea experiments	Performed the experiments	Investigation	YES
5050705	27716060	MG	2	performed all biochemical and mea experiments|analysed data	analysed data	Analyzed the data	Formal analysis	YES
5050705	27716060	VYP	2	performed all biochemical and mea experiments|analysed data	performed all biochemical and mea experiments	Performed the experiments	Investigation	YES
5050705	27716060	VYP	2	performed all biochemical and mea experiments|analysed data	analysed data	Analyzed the data	Formal analysis	YES
3702014	23827470	Connor Emdin	2	conceived of the study, contributed to the design of the study, performed the systematic search and data analysis and contributed to the final manuscript	conceived of the study, contributed to the design of the study, performed the systematic search and data analysis and contributed to the final manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Resources|Writing - Review & Editing	YES
3702014	23827470	Nicholas Chong	2	performed the systematic search and contributed to the final manuscript	performed the systematic search and contributed to the final manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
3702014	23827470	Peggy Millson	2	contributed to the design of the study and the final manuscript	contributed to the design of the study and the final manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
6471462	30871056	A.D.M.	CRediT	Conceptualization|Data curation|Formal analysis|Investigation|Methodology|Writing--original draft|Writing--review & editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6471462	30871056	A.D.M.	CRediT	Conceptualization|Data curation|Formal analysis|Investigation|Methodology|Writing--original draft|Writing--review & editing	Data curation	Analyzed the data	Data curation	YES
6471462	30871056	A.D.M.	CRediT	Conceptualization|Data curation|Formal analysis|Investigation|Methodology|Writing--original draft|Writing--review & editing	Formal analysis	Analyzed the data	Formal analysis	YES
6471462	30871056	A.D.M.	CRediT	Conceptualization|Data curation|Formal analysis|Investigation|Methodology|Writing--original draft|Writing--review & editing	Investigation	Performed the experiments	Investigation	YES
6471462	30871056	A.D.M.	CRediT	Conceptualization|Data curation|Formal analysis|Investigation|Methodology|Writing--original draft|Writing--review & editing	Methodology	Performed the experiments	Methodology	YES
6471462	30871056	A.D.M.	CRediT	Conceptualization|Data curation|Formal analysis|Investigation|Methodology|Writing--original draft|Writing--review & editing	Writing--original draft	Wrote the paper	Writing - Original Draft	YES
6471462	30871056	A.D.M.	CRediT	Conceptualization|Data curation|Formal analysis|Investigation|Methodology|Writing--original draft|Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6471462	30871056	E.B.	CRediT	Supervision|Writing--review & editing	Supervision	-	Supervision	YES
6471462	30871056	E.B.	CRediT	Supervision|Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6471462	30871056	E.G.	CRediT	Supervision	Supervision	-	Supervision	YES
6471462	30871056	G.C.	CRediT	Formal analysis	Formal analysis	Analyzed the data	Formal analysis	YES
6471462	30871056	G.T.	CRediT	Resources|Supervision	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6471462	30871056	G.T.	CRediT	Resources|Supervision	Supervision	-	Supervision	YES
6471462	30871056	M.C.	CRediT	Resources|Supervision	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6471462	30871056	M.C.	CRediT	Resources|Supervision	Supervision	-	Supervision	YES
6471462	30871056	M.H.	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
6471462	30871056	M.R.	CRediT	Conceptualization|Data curation|Formal analysis|Funding acquisition|Project administration|Resources|Supervision|Writing--original draft|Writing--review & editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6471462	30871056	M.R.	CRediT	Conceptualization|Data curation|Formal analysis|Funding acquisition|Project administration|Resources|Supervision|Writing--original draft|Writing--review & editing	Data curation	Analyzed the data	Data curation	YES
6471462	30871056	M.R.	CRediT	Conceptualization|Data curation|Formal analysis|Funding acquisition|Project administration|Resources|Supervision|Writing--original draft|Writing--review & editing	Formal analysis	Analyzed the data	Formal analysis	YES
6471462	30871056	M.R.	CRediT	Conceptualization|Data curation|Formal analysis|Funding acquisition|Project administration|Resources|Supervision|Writing--original draft|Writing--review & editing	Funding acquisition	-	Funding acquisition	YES
6471462	30871056	M.R.	CRediT	Conceptualization|Data curation|Formal analysis|Funding acquisition|Project administration|Resources|Supervision|Writing--original draft|Writing--review & editing	Project administration	-	Project administration	YES
6471462	30871056	M.R.	CRediT	Conceptualization|Data curation|Formal analysis|Funding acquisition|Project administration|Resources|Supervision|Writing--original draft|Writing--review & editing	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6471462	30871056	M.R.	CRediT	Conceptualization|Data curation|Formal analysis|Funding acquisition|Project administration|Resources|Supervision|Writing--original draft|Writing--review & editing	Supervision	-	Supervision	YES
6471462	30871056	M.R.	CRediT	Conceptualization|Data curation|Formal analysis|Funding acquisition|Project administration|Resources|Supervision|Writing--original draft|Writing--review & editing	Writing--original draft	Wrote the paper	Writing - Original Draft	YES
6471462	30871056	M.R.	CRediT	Conceptualization|Data curation|Formal analysis|Funding acquisition|Project administration|Resources|Supervision|Writing--original draft|Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6471462	30871056	N.M.	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
6471462	30871056	R.R.D.	CRediT	Resources|Supervision|Writing--review & editing	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6471462	30871056	R.R.D.	CRediT	Resources|Supervision|Writing--review & editing	Supervision	-	Supervision	YES
6471462	30871056	R.R.D.	CRediT	Resources|Supervision|Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6471462	30871056	R.Y.	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
4398551	25874697	BG	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398551	25874697	DTN	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398551	25874697	DTN	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398551	25874697	DTN	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398551	25874697	DV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398551	25874697	DV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398551	25874697	DV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398551	25874697	DV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398551	25874697	JA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398551	25874697	JA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398551	25874697	JA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398551	25874697	LT	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398551	25874697	PDC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398551	25874697	PDC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398551	25874697	PDC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398551	25874697	RV	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5447745	28611814	FL	2	revised the manuscript critically for important intellectual content	revised the manuscript critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5447745	28611814	PJ	2	interpreted and prepared all the figures and tables	interpreted and prepared all the figures and tables	Analyzed the data	Formal analysis|Visualization	YES
5447745	28611814	SJ	2	mapped genetic male sterility traits and collected and analyzed all the data	mapped genetic male sterility traits and collected and analyzed all the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5447745	28611814	YJ	2	analyzed the qrt-pcr data	analyzed the qrt-pcr data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5447745	28611814	YS	2	contributed to the conception and design of the work and created the draft of the manuscript	contributed to the conception and design of the work and created the draft of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5447745	28611814	YW	2	constructed the genetic map for the work	constructed the genetic map for the work	Performed the experiments	Investigation	YES
3702919	23830642	All other authors	2	contributed to the design of the project, data analysis and subsequent drafts	contributed to the design of the project, data analysis and subsequent drafts	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Original Draft	YES
3702919	23830642	GP	2	designed, implemented, analyzed and wrote the first and subsequent drafts of this article	designed, implemented, analyzed and wrote the first and subsequent drafts of this article	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5050850	27716130	AD	2	conceived of the study	conceived of the study	Conceived and designed the experiments	Conceptualization	YES
5050850	27716130	AL	2	conceived of the study	conceived of the study	Conceived and designed the experiments	Conceptualization	YES
5050850	27716130	KHA	2	final manuscript was read and approved by all authors	final manuscript was read and approved by all authors	Wrote the paper	Writing - Review & Editing	YES
5050850	27716130	RHM	2	conceived of the study	conceived of the study	Conceived and designed the experiments	Conceptualization	YES
6471481	30866489	A.D.H.	CRediT	Investigation|Writing-review & editing|Project administration	Investigation	Performed the experiments	Investigation	YES
6471481	30866489	A.D.H.	CRediT	Investigation|Writing-review & editing|Project administration	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6471481	30866489	A.D.H.	CRediT	Investigation|Writing-review & editing|Project administration	Project administration	-	Project administration	YES
6471481	30866489	A.P.	CRediT	Conceptualization|Methodology|Software|Validation|Investigation|Writing-review & editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6471481	30866489	A.P.	CRediT	Conceptualization|Methodology|Software|Validation|Investigation|Writing-review & editing	Methodology	Performed the experiments	Methodology	YES
6471481	30866489	A.P.	CRediT	Conceptualization|Methodology|Software|Validation|Investigation|Writing-review & editing	Software	Contributed reagents/materials/analysis tools	Software	YES
6471481	30866489	A.P.	CRediT	Conceptualization|Methodology|Software|Validation|Investigation|Writing-review & editing	Validation	Performed the experiments	Validation	YES
6471481	30866489	A.P.	CRediT	Conceptualization|Methodology|Software|Validation|Investigation|Writing-review & editing	Investigation	Performed the experiments	Investigation	YES
6471481	30866489	A.P.	CRediT	Conceptualization|Methodology|Software|Validation|Investigation|Writing-review & editing	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6471481	30866489	B.G.	CRediT	Conceptualization|Methodology|Software|Validation|Investigation|Data curation|Writing-original draft preparation|Writing-review & editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6471481	30866489	B.G.	CRediT	Conceptualization|Methodology|Software|Validation|Investigation|Data curation|Writing-original draft preparation|Writing-review & editing	Methodology	Performed the experiments	Methodology	YES
6471481	30866489	B.G.	CRediT	Conceptualization|Methodology|Software|Validation|Investigation|Data curation|Writing-original draft preparation|Writing-review & editing	Software	Contributed reagents/materials/analysis tools	Software	YES
6471481	30866489	B.G.	CRediT	Conceptualization|Methodology|Software|Validation|Investigation|Data curation|Writing-original draft preparation|Writing-review & editing	Validation	Performed the experiments	Validation	YES
6471481	30866489	B.G.	CRediT	Conceptualization|Methodology|Software|Validation|Investigation|Data curation|Writing-original draft preparation|Writing-review & editing	Investigation	Performed the experiments	Investigation	YES
6471481	30866489	B.G.	CRediT	Conceptualization|Methodology|Software|Validation|Investigation|Data curation|Writing-original draft preparation|Writing-review & editing	Data curation	Analyzed the data	Data curation	YES
6471481	30866489	B.G.	CRediT	Conceptualization|Methodology|Software|Validation|Investigation|Data curation|Writing-original draft preparation|Writing-review & editing	Writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
6471481	30866489	B.G.	CRediT	Conceptualization|Methodology|Software|Validation|Investigation|Data curation|Writing-original draft preparation|Writing-review & editing	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6471481	30866489	C.L.	CRediT	Investigation|Writing-review & editing|Project administration	Investigation	Performed the experiments	Investigation	YES
6471481	30866489	C.L.	CRediT	Investigation|Writing-review & editing|Project administration	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6471481	30866489	C.L.	CRediT	Investigation|Writing-review & editing|Project administration	Project administration	-	Project administration	YES
6471481	30866489	R.C.	CRediT	Investigation|Writing-review & editing|Project administration|Funding acquisition	Investigation	Performed the experiments	Investigation	YES
6471481	30866489	R.C.	CRediT	Investigation|Writing-review & editing|Project administration|Funding acquisition	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6471481	30866489	R.C.	CRediT	Investigation|Writing-review & editing|Project administration|Funding acquisition	Project administration	-	Project administration	YES
6471481	30866489	R.C.	CRediT	Investigation|Writing-review & editing|Project administration|Funding acquisition	Funding acquisition	-	Funding acquisition	YES
6471481	30866489	S.A.T.	CRediT	Investigation|Writing-review & editing|Project administration|Funding acquisition	Investigation	Performed the experiments	Investigation	YES
6471481	30866489	S.A.T.	CRediT	Investigation|Writing-review & editing|Project administration|Funding acquisition	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6471481	30866489	S.A.T.	CRediT	Investigation|Writing-review & editing|Project administration|Funding acquisition	Project administration	-	Project administration	YES
6471481	30866489	S.A.T.	CRediT	Investigation|Writing-review & editing|Project administration|Funding acquisition	Funding acquisition	-	Funding acquisition	YES
6471481	30866489	X.Y.X.	CRediT	Conceptualization|Methodology|Validation|Investigation|Resources|Data curation|Writing-review & editing|Supervision|Project administration|Funding acquisition	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6471481	30866489	X.Y.X.	CRediT	Conceptualization|Methodology|Validation|Investigation|Resources|Data curation|Writing-review & editing|Supervision|Project administration|Funding acquisition	Methodology	Performed the experiments	Methodology	YES
6471481	30866489	X.Y.X.	CRediT	Conceptualization|Methodology|Validation|Investigation|Resources|Data curation|Writing-review & editing|Supervision|Project administration|Funding acquisition	Validation	Performed the experiments	Validation	YES
6471481	30866489	X.Y.X.	CRediT	Conceptualization|Methodology|Validation|Investigation|Resources|Data curation|Writing-review & editing|Supervision|Project administration|Funding acquisition	Investigation	Performed the experiments	Investigation	YES
6471481	30866489	X.Y.X.	CRediT	Conceptualization|Methodology|Validation|Investigation|Resources|Data curation|Writing-review & editing|Supervision|Project administration|Funding acquisition	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6471481	30866489	X.Y.X.	CRediT	Conceptualization|Methodology|Validation|Investigation|Resources|Data curation|Writing-review & editing|Supervision|Project administration|Funding acquisition	Data curation	Analyzed the data	Data curation	YES
6471481	30866489	X.Y.X.	CRediT	Conceptualization|Methodology|Validation|Investigation|Resources|Data curation|Writing-review & editing|Supervision|Project administration|Funding acquisition	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6471481	30866489	X.Y.X.	CRediT	Conceptualization|Methodology|Validation|Investigation|Resources|Data curation|Writing-review & editing|Supervision|Project administration|Funding acquisition	Supervision	-	Supervision	YES
6471481	30866489	X.Y.X.	CRediT	Conceptualization|Methodology|Validation|Investigation|Resources|Data curation|Writing-review & editing|Supervision|Project administration|Funding acquisition	Project administration	-	Project administration	YES
6471481	30866489	X.Y.X.	CRediT	Conceptualization|Methodology|Validation|Investigation|Resources|Data curation|Writing-review & editing|Supervision|Project administration|Funding acquisition	Funding acquisition	-	Funding acquisition	YES
6471481	30866489	Y.H.	CRediT	Investigation|Writing-review & editing	Investigation	Performed the experiments	Investigation	YES
6471481	30866489	Y.H.	CRediT	Investigation|Writing-review & editing	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
5447751	28611818	All authors	PLoS52	reviewed and approved the final manuscript	reviewed and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5447751	28611818	LZ	PLoS52	conceived and designed the experiments|performed the experiments, analyzed the data and drafted the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5447751	28611818	LZ	PLoS52	conceived and designed the experiments|performed the experiments, analyzed the data and drafted the manuscript	performed the experiments, analyzed the data and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5447751	28611818	MV	PLoS52	conceived and designed the experiments|critically revised the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5447751	28611818	MV	PLoS52	conceived and designed the experiments|critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
3706634	23838151	All the authors	2	contributed equally for this study	contributed equally for this study	-	-	NO
4398553	25874792	JS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398553	25874792	JS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398553	25874792	JS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398553	25874792	JS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398553	25874792	PH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398553	25874792	PH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398553	25874792	PH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398553	25874792	PH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398553	25874792	TV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398553	25874792	TV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398553	25874792	TV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398553	25874792	TV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6471532	30901927	J.T.	CRediT	Conceptualization|methodology	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6471532	30901927	J.T.	CRediT	Conceptualization|methodology	methodology	Performed the experiments	Methodology	YES
6471532	30901927	S.B.	CRediT	Conceptualization|methodology|resources	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6471532	30901927	S.B.	CRediT	Conceptualization|methodology|resources	methodology	Performed the experiments	Methodology	YES
6471532	30901927	S.B.	CRediT	Conceptualization|methodology|resources	resources	Contributed reagents/materials/analysis tools	Resources	YES
6471532	30901927	Y.E.A.	CRediT	Conceptualization|methodology|validation|formal analysis|investigation|writing--original draft preparation|visualization|supervision|project administration	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6471532	30901927	Y.E.A.	CRediT	Conceptualization|methodology|validation|formal analysis|investigation|writing--original draft preparation|visualization|supervision|project administration	methodology	Performed the experiments	Methodology	YES
6471532	30901927	Y.E.A.	CRediT	Conceptualization|methodology|validation|formal analysis|investigation|writing--original draft preparation|visualization|supervision|project administration	validation	Performed the experiments	Validation	YES
6471532	30901927	Y.E.A.	CRediT	Conceptualization|methodology|validation|formal analysis|investigation|writing--original draft preparation|visualization|supervision|project administration	formal analysis	Analyzed the data	Formal analysis	YES
6471532	30901927	Y.E.A.	CRediT	Conceptualization|methodology|validation|formal analysis|investigation|writing--original draft preparation|visualization|supervision|project administration	investigation	Performed the experiments	Investigation	YES
6471532	30901927	Y.E.A.	CRediT	Conceptualization|methodology|validation|formal analysis|investigation|writing--original draft preparation|visualization|supervision|project administration	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6471532	30901927	Y.E.A.	CRediT	Conceptualization|methodology|validation|formal analysis|investigation|writing--original draft preparation|visualization|supervision|project administration	visualization	Analyzed the data	Visualization	YES
6471532	30901927	Y.E.A.	CRediT	Conceptualization|methodology|validation|formal analysis|investigation|writing--original draft preparation|visualization|supervision|project administration	supervision	-	Supervision	YES
6471532	30901927	Y.E.A.	CRediT	Conceptualization|methodology|validation|formal analysis|investigation|writing--original draft preparation|visualization|supervision|project administration	project administration	-	Project administration	YES
6471532	30901927	Y.N.K.	CRediT	Conceptualization|methodology|formal analysis|resources|writing--original draft preparation|visualization|supervision|project administration|funding acquisition	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6471532	30901927	Y.N.K.	CRediT	Conceptualization|methodology|formal analysis|resources|writing--original draft preparation|visualization|supervision|project administration|funding acquisition	methodology	Performed the experiments	Methodology	YES
6471532	30901927	Y.N.K.	CRediT	Conceptualization|methodology|formal analysis|resources|writing--original draft preparation|visualization|supervision|project administration|funding acquisition	formal analysis	Analyzed the data	Formal analysis	YES
6471532	30901927	Y.N.K.	CRediT	Conceptualization|methodology|formal analysis|resources|writing--original draft preparation|visualization|supervision|project administration|funding acquisition	resources	Contributed reagents/materials/analysis tools	Resources	YES
6471532	30901927	Y.N.K.	CRediT	Conceptualization|methodology|formal analysis|resources|writing--original draft preparation|visualization|supervision|project administration|funding acquisition	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6471532	30901927	Y.N.K.	CRediT	Conceptualization|methodology|formal analysis|resources|writing--original draft preparation|visualization|supervision|project administration|funding acquisition	visualization	Analyzed the data	Visualization	YES
6471532	30901927	Y.N.K.	CRediT	Conceptualization|methodology|formal analysis|resources|writing--original draft preparation|visualization|supervision|project administration|funding acquisition	supervision	-	Supervision	YES
6471532	30901927	Y.N.K.	CRediT	Conceptualization|methodology|formal analysis|resources|writing--original draft preparation|visualization|supervision|project administration|funding acquisition	project administration	-	Project administration	YES
6471532	30901927	Y.N.K.	CRediT	Conceptualization|methodology|formal analysis|resources|writing--original draft preparation|visualization|supervision|project administration|funding acquisition	funding acquisition	-	Funding acquisition	YES
5053085	27716141	DG	2	conceived and planned the study|wrote the manuscript	conceived and planned the study	Conceived and designed the experiments	Conceptualization	YES
5053085	27716141	DG	2	conceived and planned the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5053085	27716141	JC	2	conceived and planned the study|collected and extracted total rnas for next-generation sequencing|analyzed the sequencing data|carried out the experimental work|wrote the manuscript	conceived and planned the study	Conceived and designed the experiments	Conceptualization	YES
5053085	27716141	JC	2	conceived and planned the study|collected and extracted total rnas for next-generation sequencing|analyzed the sequencing data|carried out the experimental work|wrote the manuscript	collected and extracted total rnas for next-generation sequencing	Performed the experiments	Investigation	YES
5053085	27716141	JC	2	conceived and planned the study|collected and extracted total rnas for next-generation sequencing|analyzed the sequencing data|carried out the experimental work|wrote the manuscript	analyzed the sequencing data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5053085	27716141	JC	2	conceived and planned the study|collected and extracted total rnas for next-generation sequencing|analyzed the sequencing data|carried out the experimental work|wrote the manuscript	carried out the experimental work	Performed the experiments	Investigation	YES
5053085	27716141	JC	2	conceived and planned the study|collected and extracted total rnas for next-generation sequencing|analyzed the sequencing data|carried out the experimental work|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5053085	27716141	JQ	2	analyzed the sequencing data	analyzed the sequencing data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5053085	27716141	KK	2	carried out the experimental work	carried out the experimental work	Performed the experiments	Investigation	YES
5053085	27716141	LL	2	conceived and planned the study	conceived and planned the study	Conceived and designed the experiments	Conceptualization	YES
5053085	27716141	XC	2	carried out the experimental work	carried out the experimental work	Performed the experiments	Investigation	YES
5053085	27716141	YL	2	carried out the experimental work	carried out the experimental work	Performed the experiments	Investigation	YES
5053085	27716141	ZQ	2	collected and extracted total rnas for next-generation sequencing	collected and extracted total rnas for next-generation sequencing	Performed the experiments	Investigation	YES
3708353	23841994	SG	2	was the sole author of this article	was the sole author of this article	-	-	NO
4398554	25876153	AB	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4398554	25876153	AB	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4398554	25876153	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398554	25876153	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398554	25876153	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398554	25876153	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398554	25876153	BRP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398554	25876153	BRP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4398554	25876153	BRP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4398554	25876153	PA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398554	25876153	PA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398554	25876153	PA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398554	25876153	PA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5447759	28611817	AK	2	analyzed the data and wrote the manuscript|revised the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5447759	28611817	AK	2	analyzed the data and wrote the manuscript|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5447759	28611817	DT	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5447759	28611817	HL	2	initiated and designed the experiment|revised the manuscript	initiated and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5447759	28611817	HL	2	initiated and designed the experiment|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5447759	28611817	HZ	2	performed the experiments and collected the data|analyzed the data and wrote the manuscript	performed the experiments and collected the data	Performed the experiments	Investigation	YES
5447759	28611817	HZ	2	performed the experiments and collected the data|analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4398555	25875096	AM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4398555	25875096	AM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398555	25875096	KM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398555	25875096	KO	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398555	25875096	KO	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398555	25875096	KO	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398555	25875096	MA	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398555	25875096	MA	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398555	25875096	MA	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398555	25875096	ST	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398555	25875096	TH	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398555	25875096	TH	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398555	25875096	TH	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398555	25875096	TK	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4398555	25875096	TK	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398555	25875096	TN	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398555	25875096	TN	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398555	25875096	TY	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398555	25875096	TY	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398555	25875096	YS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4398555	25875096	YS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
6471564	30813646	A.M.G.	2	designed and wrote the paper	designed and wrote the paper	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
6471564	30813646	C.C.	2	designed and wrote the paper	designed and wrote the paper	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
6471564	30813646	D.M.T.	2	designed and wrote the paper	designed and wrote the paper	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
6471564	30813646	R.I.T.	2	designed and wrote the paper	designed and wrote the paper	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
4419220	25977922	Zhijian Cai	5	provided the same effort as Jianzhang Wu	provided the same effort as Jianzhang Wu	-	-	NO
5447769	28611811	AA	2	formulated the idea|wrote the manuscript	formulated the idea	Conceived and designed the experiments	Conceptualization	YES
5447769	28611811	AA	2	formulated the idea|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5447769	28611811	TS	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5447769	28611811	The authors	2	confirmed their contribution of this work and prepared it for publication|declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	confirmed their contribution of this work and prepared it for publication	-	-	NO
5447769	28611811	The authors	2	confirmed their contribution of this work and prepared it for publication|declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	Performed the experiments	Investigation	YES
3709369	23845227	David Katzenstein	2	conceived and designed the study protocol|provided expert training to participants|critically revised the manuscript	conceived and designed the study protocol	Conceived and designed the experiments	Conceptualization|Methodology	YES
3709369	23845227	David Katzenstein	2	conceived and designed the study protocol|provided expert training to participants|critically revised the manuscript	provided expert training to participants	-	-	NO
3709369	23845227	David Katzenstein	2	conceived and designed the study protocol|provided expert training to participants|critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
3709369	23845227	David Sayer	2	provided expert training to participants|undertook phylogenetic and sequence analyses	provided expert training to participants	-	-	NO
3709369	23845227	David Sayer	2	provided expert training to participants|undertook phylogenetic and sequence analyses	undertook phylogenetic and sequence analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3709369	23845227	H Sohn	2	conceived and designed the study protocol|critically revised the manuscript	conceived and designed the study protocol	Conceived and designed the experiments	Conceptualization|Methodology	YES
3709369	23845227	H Sohn	2	conceived and designed the study protocol|critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
3709369	23845227	Julian Zhou	2	realized the statistical analysis	realized the statistical analysis	Analyzed the data	Formal analysis	YES
3709369	23845227	Marita Mann	2	undertook phylogenetic and sequence analyses	undertook phylogenetic and sequence analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3709369	23845227	Philip Cunningham	2	provided expert training to participants	provided expert training to participants	-	-	NO
3709369	23845227	Rami Kantor	2	conceived and designed the study protocol|provided expert training to participants|undertook phylogenetic and sequence analyses|to finalize the writing	conceived and designed the study protocol	Conceived and designed the experiments	Conceptualization|Methodology	YES
3709369	23845227	Rami Kantor	2	conceived and designed the study protocol|provided expert training to participants|undertook phylogenetic and sequence analyses|to finalize the writing	provided expert training to participants	-	-	NO
3709369	23845227	Rami Kantor	2	conceived and designed the study protocol|provided expert training to participants|undertook phylogenetic and sequence analyses|to finalize the writing	undertook phylogenetic and sequence analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3709369	23845227	Rami Kantor	2	conceived and designed the study protocol|provided expert training to participants|undertook phylogenetic and sequence analyses|to finalize the writing	to finalize the writing	Wrote the paper	-	YES
3709369	23845227	Thida Singtoroj	2	coordinated panel and workshop logistics	coordinated panel and workshop logistics	-	Project administration	YES
5053184	27716143	CPVT	PLoS52	collected samples and/or generated ngs data	collected samples and/or generated ngs data	Performed the experiments	Investigation	YES
5053184	27716143	DMB	PLoS52	performed in silico prediction and computational analyses	performed in silico prediction and computational analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5053184	27716143	EEC	PLoS52	collected samples and/or generated ngs data	collected samples and/or generated ngs data	Performed the experiments	Investigation	YES
5053184	27716143	EHH	PLoS52	performed in silico prediction and computational analyses	performed in silico prediction and computational analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5053184	27716143	GEL	PLoS52	conceived and designed the experiments|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5053184	27716143	GEL	PLoS52	conceived and designed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5053184	27716143	HC	PLoS52	collected samples and/or generated ngs data	collected samples and/or generated ngs data	Performed the experiments	Investigation	YES
5053184	27716143	LJA	PLoS52	collected samples and/or generated ngs data	collected samples and/or generated ngs data	Performed the experiments	Investigation	YES
5053184	27716143	LX	PLoS52	performed in silico prediction and computational analyses	performed in silico prediction and computational analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5053184	27716143	SGS	PLoS52	performed in silico prediction and computational analyses	performed in silico prediction and computational analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5053184	27716143	TSS	PLoS52	collected samples and/or generated ngs data	collected samples and/or generated ngs data	Performed the experiments	Investigation	YES
5053184	27716143	YZ	PLoS52	conceived and designed the experiments|performed in silico prediction and computational analyses|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5053184	27716143	YZ	PLoS52	conceived and designed the experiments|performed in silico prediction and computational analyses|wrote the paper	performed in silico prediction and computational analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5053184	27716143	YZ	PLoS52	conceived and designed the experiments|performed in silico prediction and computational analyses|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398559	25875338	IK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398559	25875338	IK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398559	25875338	IK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398559	25875338	IK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398559	25875338	JV	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398559	25875338	JV	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398559	25875338	JV	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398559	25875338	LB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398559	25875338	LB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398559	25875338	LB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398559	25875338	LB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398559	25875338	VL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4419221	25977915	Baofa Jiang	2	participated in the design of the study and interpreted the results	participated in the design of the study and interpreted the results	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
4419221	25977915	Baoxiu Jia	2	carried out circular dichroism spectra and data analysis	carried out circular dichroism spectra and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4419221	25977915	Xiaojun Yao	2	carried out molecular modeling and data analysis	carried out molecular modeling and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
4419221	25977915	Xiaolan Qu	2	carried out steady-state fluorescence spectra and data analysis	carried out steady-state fluorescence spectra and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4419221	25977915	Yueyue Kong	2	carried out uv-vis spectroscopy and helped to draft the paper	carried out uv-vis spectroscopy and helped to draft the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4419221	25977915	Yuqin Li	2	conceived and designed the study, carried out data analysis, interpreted the entire results, and drafted the paper	conceived and designed the study, carried out data analysis, interpreted the entire results, and drafted the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
5447773	28611816	AA	7	data collection	data collection	Performed the experiments	Investigation	YES
5447773	28611816	AH	7	data analysis and manuscript editing	data analysis and manuscript editing	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5447773	28611816	AK	7	data analysis and manuscript editing	data analysis and manuscript editing	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5447773	28611816	CN	7	corresponding author	corresponding author	-	-	NO
5447773	28611816	HM	7	germplasm supply	germplasm supply	-	-	NO
5447773	28611816	HS	7	data collection	data collection	Performed the experiments	Investigation	YES
5447773	28611816	IL	7	project leader	project leader	-	Supervision	YES
5447773	28611816	IT	7	data collection	data collection	Performed the experiments	Investigation	YES
5447773	28611816	JC	7	project coordinator and manuscript editing	project coordinator and manuscript editing	Wrote the paper	Project administration|Writing - Review & Editing	YES
5447773	28611816	JM	7	data collection	data collection	Performed the experiments	Investigation	YES
5447773	28611816	KS	7	germplasm supply	germplasm supply	-	-	NO
5447773	28611816	LT	7	data collection	data collection	Performed the experiments	Investigation	YES
5447773	28611816	MM	7	data collection	data collection	Performed the experiments	Investigation	YES
5447773	28611816	MO	7	data collection	data collection	Performed the experiments	Investigation	YES
5447773	28611816	NK	7	data collection	data collection	Performed the experiments	Investigation	YES
5447773	28611816	OK	7	data collection	data collection	Performed the experiments	Investigation	YES
5447773	28611816	TV	7	data collection	data collection	Performed the experiments	Investigation	YES
5447773	28611816	YI	7	data analysis	data analysis	Analyzed the data	Formal analysis	YES
5055659	27717327	BA	5	proposed that ConsNets accuracy was due to the region near the splice site	proposed that ConsNets accuracy was due to the region near the splice site	Conceived and designed the experiments	Conceptualization	YES
5055659	27717327	BJF	5	proposed ConsNet	proposed ConsNet	Conceived and designed the experiments	Conceptualization	YES
5055659	27717327	MW	5	performed the computational analysis	performed the computational analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3717402	23870277	AW	2	appraised the quality of most included papers, and wrote the manuscript|appraised the quality of a portion of the included studies for quality control|double-screened a proportion of the downloaded abstracts and consulted on decisions to include/exclude articles	appraised the quality of most included papers, and wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3717402	23870277	AW	2	appraised the quality of most included papers, and wrote the manuscript|appraised the quality of a portion of the included studies for quality control|double-screened a proportion of the downloaded abstracts and consulted on decisions to include/exclude articles	appraised the quality of a portion of the included studies for quality control	Performed the experiments	Validation	YES
3717402	23870277	AW	2	appraised the quality of most included papers, and wrote the manuscript|appraised the quality of a portion of the included studies for quality control|double-screened a proportion of the downloaded abstracts and consulted on decisions to include/exclude articles	double-screened a proportion of the downloaded abstracts and consulted on decisions to include/exclude articles	Performed the experiments	Investigation	YES
3717402	23870277	All authors	2	critically reviewed drafts and approved the final manuscript	critically reviewed drafts and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3717402	23870277	GM	2	advised on programmatic and policy implications of the findings	advised on programmatic and policy implications of the findings	-	-	NO
3717402	23870277	IB	2	appraised the quality of most included papers, and wrote the manuscript|appraised the quality of a portion of the included studies for quality control	appraised the quality of most included papers, and wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3717402	23870277	IB	2	appraised the quality of most included papers, and wrote the manuscript|appraised the quality of a portion of the included studies for quality control	appraised the quality of a portion of the included studies for quality control	Performed the experiments	Validation	YES
3717402	23870277	KI	2	advised on programmatic and policy implications of the findings	advised on programmatic and policy implications of the findings	-	-	NO
4398560	25875108	AE	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398560	25875108	BA	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398560	25875108	EDJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398560	25875108	EDJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398560	25875108	EDJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398560	25875108	EDJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398560	25875108	EDJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398560	25875108	JC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398560	25875108	KA	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4398560	25875108	KCM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398560	25875108	KCM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398560	25875108	KCM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398560	25875108	KCM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398560	25875108	KCM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398560	25875108	MS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4398560	25875108	MS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4398560	25875108	RG	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398560	25875108	TH	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4398560	25875108	TH	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
6471727	30893842	G.M.G.	CRediT	Writing--original draft|Writing--review & editing	Writing--original draft	Wrote the paper	Writing - Original Draft	YES
6471727	30893842	G.M.G.	CRediT	Writing--original draft|Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6471727	30893842	L.L.S.-B.	CRediT	Conceptualization|Funding acquisition	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6471727	30893842	L.L.S.-B.	CRediT	Conceptualization|Funding acquisition	Funding acquisition	-	Funding acquisition	YES
6471727	30893842	M.C.-F.	CRediT	Conceptualization|Funding acquisition|Data curation|Supervision|Writing--original draft	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6471727	30893842	M.C.-F.	CRediT	Conceptualization|Funding acquisition|Data curation|Supervision|Writing--original draft	Funding acquisition	-	Funding acquisition	YES
6471727	30893842	M.C.-F.	CRediT	Conceptualization|Funding acquisition|Data curation|Supervision|Writing--original draft	Data curation	Analyzed the data	Data curation	YES
6471727	30893842	M.C.-F.	CRediT	Conceptualization|Funding acquisition|Data curation|Supervision|Writing--original draft	Supervision	-	Supervision	YES
6471727	30893842	M.C.-F.	CRediT	Conceptualization|Funding acquisition|Data curation|Supervision|Writing--original draft	Writing--original draft	Wrote the paper	Writing - Original Draft	YES
6471727	30893842	M.R.P.A.	CRediT	Conceptualization|Data curation|Writing--original draft	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6471727	30893842	M.R.P.A.	CRediT	Conceptualization|Data curation|Writing--original draft	Data curation	Analyzed the data	Data curation	YES
6471727	30893842	M.R.P.A.	CRediT	Conceptualization|Data curation|Writing--original draft	Writing--original draft	Wrote the paper	Writing - Original Draft	YES
6471727	30893842	T.G.	CRediT	Data curation|Writing--review & editing	Data curation	Analyzed the data	Data curation	YES
6471727	30893842	T.G.	CRediT	Data curation|Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
3720985	23880102	AN	2	contributed to coordination of the study including regulatory aspects, interpretation of results and manuscript writing|contributed to data management, analysis and interpretation of results, and manuscript writing	contributed to coordination of the study including regulatory aspects, interpretation of results and manuscript writing	Analyzed the data|Wrote the paper	Formal analysis|Project administration|Writing - Original Draft	YES
3720985	23880102	AN	2	contributed to coordination of the study including regulatory aspects, interpretation of results and manuscript writing|contributed to data management, analysis and interpretation of results, and manuscript writing	contributed to data management, analysis and interpretation of results, and manuscript writing	Analyzed the data|Wrote the paper	Data curation|Formal analysis|Writing - Original Draft	YES
3720985	23880102	AS	2	coordinated the field implementation of study, and participated in peer writing, and interpretation of results	coordinated the field implementation of study, and participated in peer writing, and interpretation of results	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Project administration	YES
3720985	23880102	JM	2	contributed to study coordination, interpretation of results and manuscript writing	contributed to study coordination, interpretation of results and manuscript writing	Analyzed the data|Wrote the paper	Formal analysis|Project administration|Writing - Original Draft	YES
3720985	23880102	JN	2	contributed to the study design and field implementation, data analysis and results interpretation, and manuscript writing	contributed to the study design and field implementation, data analysis and results interpretation, and manuscript writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
3720985	23880102	LN	2	contributed to the study design and application for funding	contributed to the study design and application for funding	Conceived and designed the experiments	Funding acquisition|Methodology	YES
3720985	23880102	MW	2	contributed to field data collection and cleaning	contributed to field data collection and cleaning	Performed the experiments|Contributed reagents/materials/analysis tools	Data curation|Investigation|Resources	YES
3720985	23880102	NK	2	contributed to the study design and application for funding, general coordination of the study, conducted data analysis and interpretation of results, wrote the initial draft of the manuscript, received comments and edited the final submitted version	contributed to the study design and application for funding, general coordination of the study, conducted data analysis and interpretation of results, wrote the initial draft of the manuscript, received comments and edited the final submitted version	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Funding acquisition|Methodology|Project administration|Resources|Writing - Original Draft|Writing - Review & Editing	YES
3720985	23880102	NKS	2	contributed to the study design, interpretation of results and manuscript writing	contributed to the study design, interpretation of results and manuscript writing	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3720985	23880102	PK	2	contributed to study design, laboratory testing of specimens, and manuscript writing|contributed to the study design and application for funding, interpretation of results and manuscript writing	contributed to study design, laboratory testing of specimens, and manuscript writing	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
3720985	23880102	PK	2	contributed to study design, laboratory testing of specimens, and manuscript writing|contributed to the study design and application for funding, interpretation of results and manuscript writing	contributed to the study design and application for funding, interpretation of results and manuscript writing	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Funding acquisition|Methodology|Writing - Original Draft	YES
3720985	23880102	SS	2	contributed to study design and data collection, reviewed the draft manuscript and provided useful comments	contributed to study design and data collection, reviewed the draft manuscript and provided useful comments	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5447865	28611806	ES	2	conceived of and planned out this study|performed the field data collection|contributed to interpretation of the results and manuscript editing	conceived of and planned out this study	Conceived and designed the experiments	Conceptualization	YES
5447865	28611806	ES	2	conceived of and planned out this study|performed the field data collection|contributed to interpretation of the results and manuscript editing	performed the field data collection	Performed the experiments	Investigation	YES
5447865	28611806	ES	2	conceived of and planned out this study|performed the field data collection|contributed to interpretation of the results and manuscript editing	contributed to interpretation of the results and manuscript editing	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5447865	28611806	ID	2	conceived of and planned out this study|performed the field data collection|performed the analysis of remote sensing data and wrote the manuscript	conceived of and planned out this study	Conceived and designed the experiments	Conceptualization	YES
5447865	28611806	ID	2	conceived of and planned out this study|performed the field data collection|performed the analysis of remote sensing data and wrote the manuscript	performed the field data collection	Performed the experiments	Investigation	YES
5447865	28611806	ID	2	conceived of and planned out this study|performed the field data collection|performed the analysis of remote sensing data and wrote the manuscript	performed the analysis of remote sensing data and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5447865	28611806	KS	2	conceived of and planned out this study|contributed to interpretation of the results and manuscript editing	conceived of and planned out this study	Conceived and designed the experiments	Conceptualization	YES
5447865	28611806	KS	2	conceived of and planned out this study|contributed to interpretation of the results and manuscript editing	contributed to interpretation of the results and manuscript editing	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5055730	27717312	ASX	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Revised the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5055730	27717312	ASX	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Revised the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5055730	27717312	ASX	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Revised the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5055730	27717312	ASX	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Revised the paper	Revised the paper	Wrote the paper	Writing - Review & Editing	YES
5055730	27717312	FQ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5055730	27717312	FW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5055730	27717312	LMY	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5055730	27717312	MYL	PLoS5	Revised the paper	Revised the paper	Wrote the paper	Writing - Review & Editing	YES
5055730	27717312	PW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5055730	27717312	YH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Revised the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5055730	27717312	YH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Revised the paper	Performed the experiments	Performed the experiments	Investigation	YES
5055730	27717312	YH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Revised the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5055730	27717312	YH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Revised the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5055730	27717312	YH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Revised the paper	Revised the paper	Wrote the paper	Writing - Review & Editing	YES
5055730	27717312	ZSX	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4419225	25977916	Coline Ple	2	contributed equally to this work	contributed equally to this work	-	-	NO
4419225	25977916	Jerome Breton	2	contributed equally to this work	contributed equally to this work	-	-	NO
4398561	25874694	LK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398561	25874694	LK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398561	25874694	LK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398561	25874694	LK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398561	25874694	LK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6471740	30871264	All authors	2	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
6471740	30871264	D.J.B.	2	also contributed in the literature search	also contributed in the literature search	-	Formal analysis	YES
6471740	30871264	S.C.C.N.	2	equally contributed to the writing and editing of the paper	equally contributed to the writing and editing of the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6471740	30871264	T.F.G.G.C.	2	equally contributed to the writing and editing of the paper	equally contributed to the writing and editing of the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3722415	23883539	AQ	5	who conducted the data collection and analysis as part of their masters of Science of Physical Therapy degree	who conducted the data collection and analysis as part of their masters of Science of Physical Therapy degree	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3722415	23883539	DC	5	who conducted the data collection and analysis as part of their masters of Science of Physical Therapy degree	who conducted the data collection and analysis as part of their masters of Science of Physical Therapy degree	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3722415	23883539	LB	5	who conducted the data collection and analysis as part of their masters of Science of Physical Therapy degree	who conducted the data collection and analysis as part of their masters of Science of Physical Therapy degree	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3722415	23883539	MS	5	who conducted the data collection and analysis as part of their masters of Science of Physical Therapy degree	who conducted the data collection and analysis as part of their masters of Science of Physical Therapy degree	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3722415	23883539	SBR	5	provided supervision to LH	provided supervision to LH	-	Supervision	YES
3722415	23883539	SN	5	conceived and planned the study with SBR|provided supervision to LH	conceived and planned the study with SBR	Conceived and designed the experiments	Conceptualization	YES
3722415	23883539	SN	5	conceived and planned the study with SBR|provided supervision to LH	provided supervision to LH	-	Supervision	YES
4398562	25875127	KAA	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398562	25875127	KAA	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398562	25875127	KAA	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398562	25875127	KAA	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398562	25875127	OA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Proved mathematical theorems	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398562	25875127	OA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Proved mathematical theorems	Performed the experiments	Performed the experiments	Investigation	YES
4398562	25875127	OA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Proved mathematical theorems	Analyzed the data	Analyzed the data	Formal analysis	YES
4398562	25875127	OA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Proved mathematical theorems	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398562	25875127	OA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Proved mathematical theorems	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398562	25875127	OA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Proved mathematical theorems	Proved mathematical theorems	Analyzed the data	Formal analysis	YES
4398562	25875127	PS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4398562	25875127	PS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4398562	25875127	PS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398562	25875127	PS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398562	25875127	TES	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Proved mathematical theorems	Performed the experiments	Performed the experiments	Investigation	YES
4398562	25875127	TES	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Proved mathematical theorems	Analyzed the data	Analyzed the data	Formal analysis	YES
4398562	25875127	TES	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Proved mathematical theorems	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398562	25875127	TES	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Proved mathematical theorems	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398562	25875127	TES	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Proved mathematical theorems	Proved mathematical theorems	Analyzed the data	Formal analysis	YES
6471811	30832244	J.B.	CRediT	Conceptualization|Writing-original draft preparation|Supervision	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6471811	30832244	J.B.	CRediT	Conceptualization|Writing-original draft preparation|Supervision	Writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
6471811	30832244	J.B.	CRediT	Conceptualization|Writing-original draft preparation|Supervision	Supervision	-	Supervision	YES
6471811	30832244	O.O.	CRediT	Methodology|Formal analysis|Data curation|Writing-review & editing	Methodology	Performed the experiments	Methodology	YES
6471811	30832244	O.O.	CRediT	Methodology|Formal analysis|Data curation|Writing-review & editing	Formal analysis	Analyzed the data	Formal analysis	YES
6471811	30832244	O.O.	CRediT	Methodology|Formal analysis|Data curation|Writing-review & editing	Data curation	Analyzed the data	Data curation	YES
6471811	30832244	O.O.	CRediT	Methodology|Formal analysis|Data curation|Writing-review & editing	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
3732386	23911116	All authors	2	contributed to data analysis, interpretation and approved the final article	contributed to data analysis, interpretation and approved the final article	Analyzed the data	Formal analysis	YES
3732386	23911116	PN	2	conceptualized and designed the study and wrote this article	conceptualized and designed the study and wrote this article	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
3732386	23911116	SR	2	assisted with data collection and designed the qualitative database	assisted with data collection and designed the qualitative database	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
3732386	23911116	ST	2	led data collection	led data collection	Performed the experiments	Investigation	YES
4419226	25977914	Carmen Andrade	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
4419226	25977914	Francisco-Javier Ortega	PLoS52	designed the study|performed the experiments	designed the study	Conceived and designed the experiments	Methodology	YES
4419226	25977914	Francisco-Javier Ortega	PLoS52	designed the study|performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
4419226	25977914	Jose M. Vidal-Taboada	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4419226	25977914	Lorenzo Ferri	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
4419226	25977914	Manuel J. Rodriguez	PLoS52	designed the study|analyzed the data|wrote the paper	designed the study	Conceived and designed the experiments	Methodology	YES
4419226	25977914	Manuel J. Rodriguez	PLoS52	designed the study|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
4419226	25977914	Manuel J. Rodriguez	PLoS52	designed the study|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4419226	25977914	Marco Pugliese	PLoS52	participated in the design of the study and helped draft the paper	participated in the design of the study and helped draft the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4419226	25977914	Montserrat Batlle	PLoS52	designed the study|performed the experiments|analyzed the data|wrote the paper	designed the study	Conceived and designed the experiments	Methodology	YES
4419226	25977914	Montserrat Batlle	PLoS52	designed the study|performed the experiments|analyzed the data|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
4419226	25977914	Montserrat Batlle	PLoS52	designed the study|performed the experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
4419226	25977914	Montserrat Batlle	PLoS52	designed the study|performed the experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4419226	25977914	Nicole Mahy	PLoS52	analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
4419226	25977914	Nicole Mahy	PLoS52	analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5057266	27724849	AW	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5057266	27724849	DLI	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5057266	27724849	JDS	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5057266	27724849	MDMA	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5384477	28405058	All authors	2	have given approval to the final version of the manuscript	have given approval to the final version of the manuscript	-	-	NO
5449466	28620406	JS	PLoS52	performed the experiments|analyzed data|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5449466	28620406	JS	PLoS52	performed the experiments|analyzed data|wrote the manuscript	analyzed data	Analyzed the data	Formal analysis	YES
5449466	28620406	JS	PLoS52	performed the experiments|analyzed data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5449466	28620406	L-JQ	PLoS52	conceived and designed the experiments|wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5449466	28620406	L-JQ	PLoS52	conceived and designed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5449466	28620406	YG	PLoS52	conceived and designed the experiments|analyzed data|wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5449466	28620406	YG	PLoS52	conceived and designed the experiments|analyzed data|wrote the manuscript	analyzed data	Analyzed the data	Formal analysis	YES
5449466	28620406	YG	PLoS52	conceived and designed the experiments|analyzed data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5449466	28620406	ZLi	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5449466	28620406	ZLiu	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
6471858	30832389	A.D.	CRediT	Conceptualization|data curation|writing--original draft preparation|writing--review and editing|supervision	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6471858	30832389	A.D.	CRediT	Conceptualization|data curation|writing--original draft preparation|writing--review and editing|supervision	data curation	Analyzed the data	Data curation	YES
6471858	30832389	A.D.	CRediT	Conceptualization|data curation|writing--original draft preparation|writing--review and editing|supervision	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6471858	30832389	A.D.	CRediT	Conceptualization|data curation|writing--original draft preparation|writing--review and editing|supervision	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6471858	30832389	A.D.	CRediT	Conceptualization|data curation|writing--original draft preparation|writing--review and editing|supervision	supervision	-	Supervision	YES
6471858	30832389	B.P.	CRediT	methodology	methodology	Performed the experiments	Methodology	YES
6471858	30832389	L.F.	CRediT	methodology|data curation|writing--original draft preparation	methodology	Performed the experiments	Methodology	YES
6471858	30832389	L.F.	CRediT	methodology|data curation|writing--original draft preparation	data curation	Analyzed the data	Data curation	YES
6471858	30832389	L.F.	CRediT	methodology|data curation|writing--original draft preparation	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6471858	30832389	M.C.B.	CRediT	Conceptualization|writing--original draft preparation|supervision	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6471858	30832389	M.C.B.	CRediT	Conceptualization|writing--original draft preparation|supervision	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6471858	30832389	M.C.B.	CRediT	Conceptualization|writing--original draft preparation|supervision	supervision	-	Supervision	YES
6471858	30832389	P.G.	CRediT	writing--original draft preparation|writing--review and editing	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6471858	30832389	P.G.	CRediT	writing--original draft preparation|writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6471858	30832389	S.B.	CRediT	methodology	methodology	Performed the experiments	Methodology	YES
3736456	23920209	All authors	2	contributed to study design and writing the manuscript	contributed to study design and writing the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3736456	23920209	NM	2	led study design, conduct of the study, analysis and writing	led study design, conduct of the study, analysis and writing	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology	YES
5449467	28620407	GZ	2	designed experiments, supervised all experiments and edited the manuscript	designed experiments, supervised all experiments and edited the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Review & Editing	YES
5449467	28620407	HK	2	designed and performed the experiments, and was the main contributor in writing the manuscript	designed and performed the experiments, and was the main contributor in writing the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5449467	28620407	MP	2	performed some experiments	performed some experiments	Performed the experiments	Investigation	YES
5449467	28620407	RC	2	designed and performed the experiments, produced the figures and performed the statistical analyses	designed and performed the experiments, produced the figures and performed the statistical analyses	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology|Visualization	YES
5449467	28620407	RC-A	2	performed some experiments	performed some experiments	Performed the experiments	Investigation	YES
5384478	28405059	All authors	2	have given approval to the final version of the manuscript	have given approval to the final version of the manuscript	-	-	NO
6471907	30897738	A.A.	CRediT	Conceptualization|methodology|Writing - original draft|Writing - review & editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6471907	30897738	A.A.	CRediT	Conceptualization|methodology|Writing - original draft|Writing - review & editing	methodology	Performed the experiments	Methodology	YES
6471907	30897738	A.A.	CRediT	Conceptualization|methodology|Writing - original draft|Writing - review & editing	Writing - original draft	Wrote the paper	Writing - Original Draft	YES
6471907	30897738	A.A.	CRediT	Conceptualization|methodology|Writing - original draft|Writing - review & editing	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
6471907	30897738	A.S.Y.	CRediT	methodology|Writing - original draft	methodology	Performed the experiments	Methodology	YES
6471907	30897738	A.S.Y.	CRediT	methodology|Writing - original draft	Writing - original draft	Wrote the paper	Writing - Original Draft	YES
6471907	30897738	N.C.	CRediT	methodology|Writing - original draft	methodology	Performed the experiments	Methodology	YES
6471907	30897738	N.C.	CRediT	methodology|Writing - original draft	Writing - original draft	Wrote the paper	Writing - Original Draft	YES
6471907	30897738	S.S.	CRediT	Conceptualization|methodology|Writing - original draft|Writing - review & editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6471907	30897738	S.S.	CRediT	Conceptualization|methodology|Writing - original draft|Writing - review & editing	methodology	Performed the experiments	Methodology	YES
6471907	30897738	S.S.	CRediT	Conceptualization|methodology|Writing - original draft|Writing - review & editing	Writing - original draft	Wrote the paper	Writing - Original Draft	YES
6471907	30897738	S.S.	CRediT	Conceptualization|methodology|Writing - original draft|Writing - review & editing	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
6471907	30897738	Tan Suwandecha	CRediT	methodology|Writing - original draft	methodology	Performed the experiments	Methodology	YES
6471907	30897738	Tan Suwandecha	CRediT	methodology|Writing - original draft	Writing - original draft	Wrote the paper	Writing - Original Draft	YES
6471907	30897738	Teerapol Srichana	CRediT	methodology|Writing - original draft|Writing - review & editing	methodology	Performed the experiments	Methodology	YES
6471907	30897738	Teerapol Srichana	CRediT	methodology|Writing - original draft|Writing - review & editing	Writing - original draft	Wrote the paper	Writing - Original Draft	YES
6471907	30897738	Teerapol Srichana	CRediT	methodology|Writing - original draft|Writing - review & editing	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
3744818	23948440	all of the authors	4	This article was critically reviewed and approved by	This article was critically reviewed and approved by	-	-	NO
5449470	28620399	JB	2	contributed substantially to the data acquisition, processing, analysis and interpretation, and composing the manuscript	contributed substantially to the data acquisition, processing, analysis and interpretation, and composing the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Formal analysis|Investigation|Resources	YES
5449470	28620399	JM	2	contributed substantially to the conception of the work, data acquisition, processing, analysis and interpretation, and composing the manuscript	contributed substantially to the conception of the work, data acquisition, processing, analysis and interpretation, and composing the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Data curation|Formal analysis|Investigation|Resources	YES
5449470	28620399	MV	2	contributed to the field data acquisition, interpretation, and composing the manuscript	contributed to the field data acquisition, interpretation, and composing the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5449470	28620399	PD	2	contributed to the data acquisition and processing, and composing the manuscript	contributed to the data acquisition and processing, and composing the manuscript	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5449470	28620399	PP	2	contributed to the conception of the work and composing the manuscript	contributed to the conception of the work and composing the manuscript	Conceived and designed the experiments	Conceptualization	YES
5449470	28620399	TB	2	contributed to the data acquisition and processing, and composing the manuscript	contributed to the data acquisition and processing, and composing the manuscript	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
6472048	30917532	B.S.	CRediT	writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6472048	30917532	J.G.	CRediT	writing--original draft preparation|writing--review and editing	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6472048	30917532	J.G.	CRediT	writing--original draft preparation|writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6472048	30917532	J.d.N.	CRediT	Conceptualization|writing--original draft preparation|writing--review and editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6472048	30917532	J.d.N.	CRediT	Conceptualization|writing--original draft preparation|writing--review and editing	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6472048	30917532	J.d.N.	CRediT	Conceptualization|writing--original draft preparation|writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6472048	30917532	L.M.	CRediT	writing--original draft preparation|writing--review and editing	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6472048	30917532	L.M.	CRediT	writing--original draft preparation|writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6472048	30917532	R.N.	CRediT	writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
5057432	27724857	AN	2	conceived of and designed the experiments|analysed the raw rna sequencing data|drafted the manuscript	conceived of and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5057432	27724857	AN	2	conceived of and designed the experiments|analysed the raw rna sequencing data|drafted the manuscript	analysed the raw rna sequencing data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5057432	27724857	AN	2	conceived of and designed the experiments|analysed the raw rna sequencing data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5057432	27724857	LM	2	analysed the raw rna sequencing data	analysed the raw rna sequencing data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5057432	27724857	MGM	2	conceived of and designed the experiments|performed cell culturing, rna isolation, qpcr and northern blot analyses	conceived of and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5057432	27724857	MGM	2	conceived of and designed the experiments|performed cell culturing, rna isolation, qpcr and northern blot analyses	performed cell culturing, rna isolation, qpcr and northern blot analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5057432	27724857	RNA	2	with their potential targets	with their potential targets	-	-	NO
5057432	27724857	SAF	2	conceived of and designed the experiments	conceived of and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5057432	27724857	SVB	2	conceived of and designed the experiments|performed cell culturing, rna isolation, qpcr and northern blot analyses|drafted the manuscript	conceived of and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5057432	27724857	SVB	2	conceived of and designed the experiments|performed cell culturing, rna isolation, qpcr and northern blot analyses|drafted the manuscript	performed cell culturing, rna isolation, qpcr and northern blot analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5057432	27724857	SVB	2	conceived of and designed the experiments|performed cell culturing, rna isolation, qpcr and northern blot analyses|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5057432	27724857	TR	2	analysed the raw rna sequencing data	analysed the raw rna sequencing data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5057432	27724857	TT	2	conceived of and designed the experiments	conceived of and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398568	25874860	GL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the software used in analysis|Revised the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4398568	25874860	GL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the software used in analysis|Revised the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4398568	25874860	GL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the software used in analysis|Revised the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4398568	25874860	GL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the software used in analysis|Revised the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398568	25874860	GL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the software used in analysis|Revised the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4398568	25874860	GL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the software used in analysis|Revised the manuscript	Designed the software used in analysis	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
4398568	25874860	GL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the software used in analysis|Revised the manuscript	Revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4398568	25874860	JL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Designed the software used in analysis	Performed the experiments	Performed the experiments	Investigation	YES
4398568	25874860	JL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Designed the software used in analysis	Analyzed the data	Analyzed the data	Formal analysis	YES
4398568	25874860	JL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Designed the software used in analysis	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398568	25874860	JL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Designed the software used in analysis	Designed the software used in analysis	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
4398568	25874860	TZH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Designed the software used in analysis|Revised the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4398568	25874860	TZH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Designed the software used in analysis|Revised the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4398568	25874860	TZH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Designed the software used in analysis|Revised the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398568	25874860	TZH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Designed the software used in analysis|Revised the manuscript	Designed the software used in analysis	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
4398568	25874860	TZH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Designed the software used in analysis|Revised the manuscript	Revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4398568	25874860	XGL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Designed the software used in analysis|Revised the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4398568	25874860	XGL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Designed the software used in analysis|Revised the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4398568	25874860	XGL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Designed the software used in analysis|Revised the manuscript	Designed the software used in analysis	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
4398568	25874860	XGL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Designed the software used in analysis|Revised the manuscript	Revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
3752431	23972159	All authors	2	have read and approved the submitted manuscript	have read and approved the submitted manuscript	-	-	NO
3752431	23972159	BL	2	wrote the initial draft|contributed equally in this work	wrote the initial draft	Wrote the paper	Writing - Original Draft	YES
3752431	23972159	BL	2	wrote the initial draft|contributed equally in this work	contributed equally in this work	-	-	NO
3752431	23972159	CW	2	providing overall guidance|contributed equally in this work	providing overall guidance	-	Supervision	YES
3752431	23972159	CW	2	providing overall guidance|contributed equally in this work	contributed equally in this work	-	-	NO
3752431	23972159	MR	2	wrote the initial draft|contributed equally in this work	wrote the initial draft	Wrote the paper	Writing - Original Draft	YES
3752431	23972159	MR	2	wrote the initial draft|contributed equally in this work	contributed equally in this work	-	-	NO
3752431	23972159	The authors	2	contributed equally in this work	contributed equally in this work	-	-	NO
5390506	28413261	A.I.	2	supervised the research	supervised the research	-	Supervision	YES
5390506	28413261	A.v.B.	2	supervised the research	supervised the research	-	Supervision	YES
5390506	28413261	All authors	2	have given approval to the final version of the manuscript	have given approval to the final version of the manuscript	-	-	NO
5390506	28413261	C.R.	2	performed the synthesis of the spherical particles|performed the etching of the spherical particles	performed the synthesis of the spherical particles	Performed the experiments	Investigation	YES
5390506	28413261	C.R.	2	performed the synthesis of the spherical particles|performed the etching of the spherical particles	performed the etching of the spherical particles	Performed the experiments	Investigation	YES
5390506	28413261	F.H.	2	wrote the manuscript and performed the synthesis and analysis of rod-shaped particles|performed the etching of the rod-shaped particles|performed the etching of the spherical particles	wrote the manuscript and performed the synthesis and analysis of rod-shaped particles	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5390506	28413261	F.H.	2	wrote the manuscript and performed the synthesis and analysis of rod-shaped particles|performed the etching of the rod-shaped particles|performed the etching of the spherical particles	performed the etching of the rod-shaped particles	Performed the experiments	Investigation	YES
5390506	28413261	F.H.	2	wrote the manuscript and performed the synthesis and analysis of rod-shaped particles|performed the etching of the rod-shaped particles|performed the etching of the spherical particles	performed the etching of the spherical particles	Performed the experiments	Investigation	YES
5390506	28413261	W.V.	2	performed the synthesis of the spherical particles|performed the etching of the spherical particles	performed the synthesis of the spherical particles	Performed the experiments	Investigation	YES
5390506	28413261	W.V.	2	performed the synthesis of the spherical particles|performed the etching of the spherical particles	performed the etching of the spherical particles	Performed the experiments	Investigation	YES
6249199	29446055	Chris P. Gale	2	contributed to the initial concept of the paper and provided comments on previous draft versions of the manuscript	contributed to the initial concept of the paper and provided comments on previous draft versions of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
6249199	29446055	Gerry Richardson	2	contributed to the initial concept of the paper and drafted parts of the manuscript, provided extensive comments on previous draft versions and contributed to the interpretation of the results	contributed to the initial concept of the paper and drafted parts of the manuscript, provided extensive comments on previous draft versions and contributed to the interpretation of the results	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
6249199	29446055	James Lomas	2	led the drafting of the manuscript and produced the summaries of results of the analysis, as well as contributing to the production and interpretation of the results	led the drafting of the manuscript and produced the summaries of results of the analysis, as well as contributing to the production and interpretation of the results	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6249199	29446055	Laura Bojke	2	contributed to the initial concept of the paper and drafted parts of the manuscript, provided extensive comments on previous draft versions and contributed to the interpretation of the results	contributed to the initial concept of the paper and drafted parts of the manuscript, provided extensive comments on previous draft versions and contributed to the interpretation of the results	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
6249199	29446055	Miqdad Asaria	2	provided comments on several draft versions of the manuscript, contributed to the conceptualisation of the analysis and produced the code for the analysis undertaken	provided comments on several draft versions of the manuscript, contributed to the conceptualisation of the analysis and produced the code for the analysis undertaken	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Software|Writing - Original Draft	YES
6249199	29446055	Simon Walker	2	drafted parts of the manuscript, provided extensive comments on several draft versions of the manuscript, contributed to the conceptualisation of the analysis as well as contributing to the production and interpretation of the results	drafted parts of the manuscript, provided extensive comments on several draft versions of the manuscript, contributed to the conceptualisation of the analysis as well as contributing to the production and interpretation of the results	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
5057473	27724860	HJL	PLoS52	conceived the idea and designed the experiments|carried out the experiments	conceived the idea and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5057473	27724860	HJL	PLoS52	conceived the idea and designed the experiments|carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5057473	27724860	HSP	PLoS52	analyzed the data|drafted the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5057473	27724860	HSP	PLoS52	analyzed the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5057473	27724860	KL	PLoS52	conceived the idea and designed the experiments|analyzed the data|drafted the manuscript	conceived the idea and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5057473	27724860	KL	PLoS52	conceived the idea and designed the experiments|analyzed the data|drafted the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5057473	27724860	KL	PLoS52	conceived the idea and designed the experiments|analyzed the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5057473	27724860	SK	PLoS52	conceived the idea and designed the experiments|carried out the experiments|analyzed the data|drafted the manuscript	conceived the idea and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5057473	27724860	SK	PLoS52	conceived the idea and designed the experiments|carried out the experiments|analyzed the data|drafted the manuscript	carried out the experiments	Performed the experiments	Investigation	YES
5057473	27724860	SK	PLoS52	conceived the idea and designed the experiments|carried out the experiments|analyzed the data|drafted the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5057473	27724860	SK	PLoS52	conceived the idea and designed the experiments|carried out the experiments|analyzed the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4399832	25880908	JPB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399832	25880908	JPB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399832	25880908	JPB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399832	25880908	JPB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399832	25880908	SL	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4399832	25880908	SL	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4399832	25880908	ZTW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399832	25880908	ZTW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399832	25880908	ZTW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399832	25880908	ZTW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399832	25880908	ZTW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5449476	28620404	HC	2	conducted experiments	conducted experiments	Performed the experiments	Investigation	YES
5449476	28620404	HF	2	conducted experiments|analyzed data and wrote the manuscript	conducted experiments	Performed the experiments	Investigation	YES
5449476	28620404	HF	2	conducted experiments|analyzed data and wrote the manuscript	analyzed data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5449476	28620404	JD	2	conceived and designed research	conceived and designed research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5449476	28620404	MD	2	conducted experiments	conducted experiments	Performed the experiments	Investigation	YES
5449476	28620404	TW	2	conceived and designed research	conceived and designed research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5449476	28620404	WS	2	conducted experiments	conducted experiments	Performed the experiments	Investigation	YES
5449476	28620404	XL	2	conducted experiments	conducted experiments	Performed the experiments	Investigation	YES
3756231	23985346	ADH	2	contributed to the study conception and design	contributed to the study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
3756231	23985346	AMVK	2	contributed to the study conception and design|contributed to the data analysis	contributed to the study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
3756231	23985346	AMVK	2	contributed to the study conception and design|contributed to the data analysis	contributed to the data analysis	Analyzed the data	Formal analysis	YES
3756231	23985346	BR	2	contributed to the study conception and design	contributed to the study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
3756231	23985346	SBN	2	contributed to the study conception and design|contributed to the data analysis	contributed to the study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
3756231	23985346	SBN	2	contributed to the study conception and design|contributed to the data analysis	contributed to the data analysis	Analyzed the data	Formal analysis	YES
3756231	23985346	SS	2	contributed to the study conception and design|did the data collection|contributed to the data analysis	contributed to the study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
3756231	23985346	SS	2	contributed to the study conception and design|did the data collection|contributed to the data analysis	did the data collection	Performed the experiments	Investigation	YES
3756231	23985346	SS	2	contributed to the study conception and design|did the data collection|contributed to the data analysis	contributed to the data analysis	Analyzed the data	Formal analysis	YES
3756231	23985346	SSN	2	contributed to the study conception and design|contributed to the data analysis	contributed to the study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
3756231	23985346	SSN	2	contributed to the study conception and design|contributed to the data analysis	contributed to the data analysis	Analyzed the data	Formal analysis	YES
3756231	23985346	Z. All	2	coauthors further reviewed the paper critically and contributed to the various revisions	coauthors further reviewed the paper critically and contributed to the various revisions	Wrote the paper	Writing - Review & Editing	YES
3356737	22645448	E. Kousi	2	contributed equally to the paper	contributed equally to the paper	-	-	NO
3356737	22645448	I. Tsougos	2	contributed equally to the paper	contributed equally to the paper	-	-	NO
5012081	27651846	Andrew T. Tsin	2	co-designed experiment|analyzed data, interpreted results, wrote manuscript and provided other related support	co-designed experiment	Conceived and designed the experiments	Methodology	YES
5012081	27651846	Andrew T. Tsin	2	co-designed experiment|analyzed data, interpreted results, wrote manuscript and provided other related support	analyzed data, interpreted results, wrote manuscript and provided other related support	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5012081	27651846	Brandi S. Betts-Obregon	2	provided technical support|analyzed data, interpreted results, wrote manuscript and provided other related support	provided technical support	Performed the experiments	Investigation	YES
5012081	27651846	Brandi S. Betts-Obregon	2	provided technical support|analyzed data, interpreted results, wrote manuscript and provided other related support	analyzed data, interpreted results, wrote manuscript and provided other related support	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5012081	27651846	George Perry	2	analyzed data, interpreted results, wrote manuscript and provided other related support	analyzed data, interpreted results, wrote manuscript and provided other related support	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5012081	27651846	Nona Aryan	2	conceived, designed and performed experiments|analyzed data, interpreted results, wrote manuscript and provided other related support	conceived, designed and performed experiments	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
5012081	27651846	Nona Aryan	2	conceived, designed and performed experiments|analyzed data, interpreted results, wrote manuscript and provided other related support	analyzed data, interpreted results, wrote manuscript and provided other related support	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4399833	25879929	BMK	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399833	25879929	DIK	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399833	25879929	DJK	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399833	25879929	DS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399833	25879929	DS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399833	25879929	DS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399833	25879929	DS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399833	25879929	HSL	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4399833	25879929	HSN	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399833	25879929	JHH	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399833	25879929	JHH	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399833	25879929	JY	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399833	25879929	KL	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399833	25879929	YDK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399833	25879929	YDK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399833	25879929	YDK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399833	25879929	YDK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5059895	27729006	DLG	2	conceived and designed the experiment, analyzed and interpreted the data and wrote the manuscript	conceived and designed the experiment, analyzed and interpreted the data and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
5059895	27729006	GHZ	2	participated in berry sample collection, rna extraction and qrt-pcr analysis	participated in berry sample collection, rna extraction and qrt-pcr analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5059895	27729006	GYZ	2	conceived and designed the experiment, analyzed and interpreted the data and wrote the manuscript	conceived and designed the experiment, analyzed and interpreted the data and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
5059895	27729006	XXF	2	participated in berry sample collection, rna extraction and qrt-pcr analysis	participated in berry sample collection, rna extraction and qrt-pcr analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5059895	27729006	XYZ	2	participated in berry sample collection, rna extraction and qrt-pcr analysis	participated in berry sample collection, rna extraction and qrt-pcr analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5059895	27729006	YYY	2	participated in berry sample collection, rna extraction and qrt-pcr analysis	participated in berry sample collection, rna extraction and qrt-pcr analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5449477	28620402	All authors	PLoS52	reviewed and approved the final manuscript	reviewed and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5449477	28620402	J-MW	PLoS52	conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5449477	28620402	J-ZH	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5449477	28620402	MJ	PLoS52	conducted the rt-q pcr experiments	conducted the rt-q pcr experiments	Performed the experiments	Investigation	YES
5449477	28620402	Q-YS	PLoS52	conceived the study|analyzed the data|prepared the final version	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5449477	28620402	Q-YS	PLoS52	conceived the study|analyzed the data|prepared the final version	analyzed the data	Analyzed the data	Formal analysis	YES
5449477	28620402	Q-YS	PLoS52	conceived the study|analyzed the data|prepared the final version	prepared the final version	-	-	NO
5449477	28620402	R-QL	PLoS52	conducted the rt-q pcr experiments|completed the bioinformatic analyses|analyzed the data	conducted the rt-q pcr experiments	Performed the experiments	Investigation	YES
5449477	28620402	R-QL	PLoS52	conducted the rt-q pcr experiments|completed the bioinformatic analyses|analyzed the data	completed the bioinformatic analyses	Analyzed the data	Formal analysis	YES
5449477	28620402	R-QL	PLoS52	conducted the rt-q pcr experiments|completed the bioinformatic analyses|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5449477	28620402	Y-CZ	PLoS52	completed the bioinformatic analyses	completed the bioinformatic analyses	Analyzed the data	Formal analysis	YES
3763046	24004854	AK	2	helped in reading the pathology slides	helped in reading the pathology slides	Performed the experiments	Investigation	YES
3763046	24004854	BR	2	helped in the design and coordination of the study	helped in the design and coordination of the study	Conceived and designed the experiments	Methodology|Project administration	YES
3763046	24004854	CC	2	helped in the design and coordination of the study	helped in the design and coordination of the study	Conceived and designed the experiments	Methodology|Project administration	YES
3763046	24004854	KL	2	was a blind reviewer of the pathology slides and in making diagnoses	was a blind reviewer of the pathology slides and in making diagnoses	Performed the experiments	Investigation	YES
3763046	24004854	MR	2	read the pathology slides and interpretation of the data	read the pathology slides and interpretation of the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3763046	24004854	PN	2	participated in the design of the study and performed the statistical analysis	participated in the design of the study and performed the statistical analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
3763046	24004854	SJT	2	participated in the design of the study and helped analyze the data	participated in the design of the study and helped analyze the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
3763046	24004854	SK	2	participated in the design of the study and helped in recruiting study participants	participated in the design of the study and helped in recruiting study participants	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3763046	24004854	TAM	2	helped create, design, and coordinate the study	helped create, design, and coordinate the study	Conceived and designed the experiments	Methodology|Project administration	YES
3763046	24004854	TTF	2	participated in designing the study, performing data analysis, and writing the paper	participated in designing the study, performing data analysis, and writing the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5390509	28413259	All authors	2	have given approval to the final version of the manuscript	have given approval to the final version of the manuscript	-	-	NO
5073110	27484822	George Davey Smith	2	contributed to the development of paper structure, identification of relevant literature, commentary on methodologies and consideration of practical issues	contributed to the development of paper structure, identification of relevant literature, commentary on methodologies and consideration of practical issues	Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5073110	27484822	Neil Davies	2	contributed to the development of paper structure, identification of relevant literature, commentary on methodologies and consideration of practical issues	contributed to the development of paper structure, identification of relevant literature, commentary on methodologies and consideration of practical issues	Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5073110	27484822	Padraig Dixon	2	conceived and designed the study|contributed to the development of paper structure, identification of relevant literature, commentary on methodologies and consideration of practical issues|wrote the first draft, and all authors contributed to subsequent revisions	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5073110	27484822	Padraig Dixon	2	conceived and designed the study|contributed to the development of paper structure, identification of relevant literature, commentary on methodologies and consideration of practical issues|wrote the first draft, and all authors contributed to subsequent revisions	contributed to the development of paper structure, identification of relevant literature, commentary on methodologies and consideration of practical issues	Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5073110	27484822	Padraig Dixon	2	conceived and designed the study|contributed to the development of paper structure, identification of relevant literature, commentary on methodologies and consideration of practical issues|wrote the first draft, and all authors contributed to subsequent revisions	wrote the first draft, and all authors contributed to subsequent revisions	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5073110	27484822	Stephanie von Hinke	2	contributed to the development of paper structure, identification of relevant literature, commentary on methodologies and consideration of practical issues	contributed to the development of paper structure, identification of relevant literature, commentary on methodologies and consideration of practical issues	Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5073110	27484822	William Hollingworth	2	contributed to the development of paper structure, identification of relevant literature, commentary on methodologies and consideration of practical issues	contributed to the development of paper structure, identification of relevant literature, commentary on methodologies and consideration of practical issues	Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
4399835	25879666	AB	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4399835	25879666	AB	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399835	25879666	HM	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399835	25879666	HT	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4399835	25879666	MK	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4399835	25879666	MK	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399835	25879666	MS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399835	25879666	MS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399835	25879666	TK	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4399835	25879666	TK	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399835	25879666	TO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399835	25879666	TO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399835	25879666	TO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399835	25879666	TO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399835	25879666	TT	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4399835	25879666	YS	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5393911	28435185	J.-H.L.	2	contributed equally to this work	contributed equally to this work	-	-	NO
5393911	28435185	Y.-K.J.	2	contributed equally to this work	contributed equally to this work	-	-	NO
5449478	28620401	GZ	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5449478	28620401	GZ	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5449478	28620401	JZ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5449478	28620401	L. All	PLoS52	authors reviewed the manuscript	authors reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5449478	28620401	MS	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5449478	28620401	TM	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5449478	28620401	YZ	PLoS52	designed the experiments|performed the experiments|analyzed the data	designed the experiments	Conceived and designed the experiments	Methodology	YES
5449478	28620401	YZ	PLoS52	designed the experiments|performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5449478	28620401	YZ	PLoS52	designed the experiments|performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5449478	28620401	YaL	PLoS52	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5449478	28620401	YuL	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
3764307	24008177	All authors	2	participated in writing the paper and approved the final version of the manuscript	participated in writing the paper and approved the final version of the manuscript	Wrote the paper	Writing - Original Draft	YES
5385191	28110382	All authors	2	commented on and contributed to all parts of the paper	commented on and contributed to all parts of the paper	-	-	NO
5385191	28110382	Matthew Franklin	2	led the drafting and writing of the paper, contributed to the design of the economic analysis and undertook the economic analysis in stata	led the drafting and writing of the paper, contributed to the design of the economic analysis and undertook the economic analysis in stata	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5385191	28110382	Michelle Horspool	2	informed the overall design of the pleasant trial	informed the overall design of the pleasant trial	Conceived and designed the experiments	Methodology	YES
5385191	28110382	Sarah Davis	2	was the lead health economist for the pleasant trial and led the initial design of the economic analysis	was the lead health economist for the pleasant trial and led the initial design of the economic analysis	Conceived and designed the experiments	-	YES
5385191	28110382	Steven Julious	2	was chief investigator of the pleasant trial	was chief investigator of the pleasant trial	-	-	NO
5385191	28110382	Wei Sun Kua	2	conducted the systematic review of the utility values and sourced the unit costs used for the economic analysis	conducted the systematic review of the utility values and sourced the unit costs used for the economic analysis	Performed the experiments	Investigation	YES
5059910	27729004	AF	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5059910	27729004	All authors	2	revised the manuscript and approved the final version of the manuscript	revised the manuscript and approved the final version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5059910	27729004	GB	2	conceived and designed this study|wrote the manuscript	conceived and designed this study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5059910	27729004	GB	2	conceived and designed this study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5059910	27729004	ML	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4399836	25880808	CL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399836	25880808	EC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399836	25880808	EC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399836	25880808	EC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399836	25880808	FD	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399836	25880808	GP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399836	25880808	GP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399836	25880808	GP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399836	25880808	IV	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4399836	25880808	JP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399836	25880808	JP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399836	25880808	JP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399836	25880808	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399836	25880808	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399836	25880808	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399836	25880808	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399836	25880808	MG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4399836	25880808	MJS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399836	25880808	MJS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399836	25880808	MJS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399836	25880808	MJS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399836	25880808	ML	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399836	25880808	MUM	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399836	25880808	MUM	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399836	25880808	SF	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4399836	25880808	SO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399836	25880808	SO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399836	25880808	SO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399836	25880808	SO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399836	25880808	TI	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4399836	25880808	TI	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4399836	25880808	TI	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399836	25880808	VB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4399836	25880808	VB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4399836	25880808	VB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5449480	28620408	JJ	PLoS52	designed the study|performed experiments|analyzed the data|drafted the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5449480	28620408	JJ	PLoS52	designed the study|performed experiments|analyzed the data|drafted the manuscript	performed experiments	Performed the experiments	Investigation	YES
5449480	28620408	JJ	PLoS52	designed the study|performed experiments|analyzed the data|drafted the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5449480	28620408	JJ	PLoS52	designed the study|performed experiments|analyzed the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5449480	28620408	JS	PLoS52	designed the study|drafted the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5449480	28620408	JS	PLoS52	designed the study|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5449480	28620408	LS	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5449480	28620408	TX	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5449480	28620408	ZX	PLoS52	designed the study|analyzed the data|drafted the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5449480	28620408	ZX	PLoS52	designed the study|analyzed the data|drafted the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5449480	28620408	ZX	PLoS52	designed the study|analyzed the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4399837	25880762	JLC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399837	25880762	JLC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399837	25880762	KJC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399837	25880762	KJC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399837	25880762	KJC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399837	25880762	KJC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399837	25880762	MRC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399837	25880762	MRC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399837	25880762	MRC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399837	25880762	MRC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3772323	24029015	GM	2	conceptualized the review and drafted manuscripts|contributed to the screening, quality assessment and writing of the manuscript	conceptualized the review and drafted manuscripts	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
3772323	24029015	GM	2	conceptualized the review and drafted manuscripts|contributed to the screening, quality assessment and writing of the manuscript	contributed to the screening, quality assessment and writing of the manuscript	Performed the experiments|Wrote the paper	Investigation|Validation|Writing - Original Draft	YES
3772323	24029015	JS	2	contributed to the literature search and the critical review of the manuscript	contributed to the literature search and the critical review of the manuscript	Wrote the paper	Formal analysis|Writing - Review & Editing	YES
3772323	24029015	KT	2	contributed to the literature search and the critical review of the manuscript	contributed to the literature search and the critical review of the manuscript	Wrote the paper	Formal analysis|Writing - Review & Editing	YES
3772323	24029015	NF	2	contributed to the literature search and the critical review of the manuscript	contributed to the literature search and the critical review of the manuscript	Wrote the paper	Formal analysis|Writing - Review & Editing	YES
3772323	24029015	PF	2	contributed to the literature search and the critical review of the manuscript	contributed to the literature search and the critical review of the manuscript	Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5427089	28238151	AI	2	developed the study design|led the data collection|supported the data analysis and interpretation of the results, and provided detailed revisions of earlier versions of the manuscript	developed the study design	Conceived and designed the experiments	Methodology	YES
5427089	28238151	AI	2	developed the study design|led the data collection|supported the data analysis and interpretation of the results, and provided detailed revisions of earlier versions of the manuscript	led the data collection	Performed the experiments	Investigation	YES
5427089	28238151	AI	2	developed the study design|led the data collection|supported the data analysis and interpretation of the results, and provided detailed revisions of earlier versions of the manuscript	supported the data analysis and interpretation of the results, and provided detailed revisions of earlier versions of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5427089	28238151	JC	2	developed the study design|supported the data analysis and interpretation of the results, and provided detailed revisions of earlier versions of the manuscript	developed the study design	Conceived and designed the experiments	Methodology	YES
5427089	28238151	JC	2	developed the study design|supported the data analysis and interpretation of the results, and provided detailed revisions of earlier versions of the manuscript	supported the data analysis and interpretation of the results, and provided detailed revisions of earlier versions of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5427089	28238151	JR	2	developed the study design|led the data collection|supported the data analysis and interpretation of the results, and provided detailed revisions of earlier versions of the manuscript	developed the study design	Conceived and designed the experiments	Methodology	YES
5427089	28238151	JR	2	developed the study design|led the data collection|supported the data analysis and interpretation of the results, and provided detailed revisions of earlier versions of the manuscript	led the data collection	Performed the experiments	Investigation	YES
5427089	28238151	JR	2	developed the study design|led the data collection|supported the data analysis and interpretation of the results, and provided detailed revisions of earlier versions of the manuscript	supported the data analysis and interpretation of the results, and provided detailed revisions of earlier versions of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5427089	28238151	PM	2	developed the study design|conducted the analysis and drafted the first version of the manuscript	developed the study design	Conceived and designed the experiments	Methodology	YES
5427089	28238151	PM	2	developed the study design|conducted the analysis and drafted the first version of the manuscript	conducted the analysis and drafted the first version of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5427089	28238151	SV	2	developed the study design|supported the data analysis and interpretation of the results, and provided detailed revisions of earlier versions of the manuscript	developed the study design	Conceived and designed the experiments	Methodology	YES
5427089	28238151	SV	2	developed the study design|supported the data analysis and interpretation of the results, and provided detailed revisions of earlier versions of the manuscript	supported the data analysis and interpretation of the results, and provided detailed revisions of earlier versions of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
3356741	22645456	F. Noacks	2	have contributed equally to this work	have contributed equally to this work	-	-	NO
3356741	22645456	S. A. Mohamed	2	have contributed equally to this work	have contributed equally to this work	-	-	NO
5059922	27729005	AMB	2	performed the genome analysis|wrote the manuscript	performed the genome analysis	Performed the experiments	Investigation	YES
5059922	27729005	AMB	2	performed the genome analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5059922	27729005	BVH	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5059922	27729005	DW	2	were responsible for sequencing and assembly|performed the genome analysis|wrote the manuscript	were responsible for sequencing and assembly	Performed the experiments	Investigation	YES
5059922	27729005	DW	2	were responsible for sequencing and assembly|performed the genome analysis|wrote the manuscript	performed the genome analysis	Performed the experiments	Investigation	YES
5059922	27729005	DW	2	were responsible for sequencing and assembly|performed the genome analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5059922	27729005	JB	2	performed the genome analysis	performed the genome analysis	Performed the experiments	Investigation	YES
5059922	27729005	JK	2	were responsible for sequencing and assembly|performed the genome analysis	were responsible for sequencing and assembly	Performed the experiments	Investigation	YES
5059922	27729005	JK	2	were responsible for sequencing and assembly|performed the genome analysis	performed the genome analysis	Performed the experiments	Investigation	YES
5059922	27729005	KB	2	performed the genome analysis|wrote the manuscript	performed the genome analysis	Performed the experiments	Investigation	YES
5059922	27729005	KB	2	performed the genome analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5059922	27729005	KP	2	conceived and designed the study|performed the genome analysis|wrote the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5059922	27729005	KP	2	conceived and designed the study|performed the genome analysis|wrote the manuscript	performed the genome analysis	Performed the experiments	Investigation	YES
5059922	27729005	KP	2	conceived and designed the study|performed the genome analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5059922	27729005	TVN	2	conceived and designed the study|isolated the dna|performed the genome analysis|wrote the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5059922	27729005	TVN	2	conceived and designed the study|isolated the dna|performed the genome analysis|wrote the manuscript	isolated the dna	Performed the experiments	Investigation	YES
5059922	27729005	TVN	2	conceived and designed the study|isolated the dna|performed the genome analysis|wrote the manuscript	performed the genome analysis	Performed the experiments	Investigation	YES
5059922	27729005	TVN	2	conceived and designed the study|isolated the dna|performed the genome analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3776134	23849225	All authors	2	contributed to the editing process and approved the final version of the manuscript as submitted	contributed to the editing process and approved the final version of the manuscript as submitted	Wrote the paper	Writing - Review & Editing	YES
3776134	23849225	WD	2	wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
5449717	28620403	AMD	2	conceived, designed and developed the concepts expressed in this article	conceived, designed and developed the concepts expressed in this article	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5449717	28620403	All authors	2	listed, have made substantial, direct and intellectual contribution to the work, and approved it for publication	listed, have made substantial, direct and intellectual contribution to the work, and approved it for publication	-	-	NO
5449717	28620403	FM	2	mainly wrote the article|conceived, designed and developed the concepts expressed in this article	mainly wrote the article	Wrote the paper	Writing - Original Draft	YES
5449717	28620403	FM	2	mainly wrote the article|conceived, designed and developed the concepts expressed in this article	conceived, designed and developed the concepts expressed in this article	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4423002	26000297	Klaus Tiroch	2	shared senior author contribution	shared senior author contribution	-	-	NO
4423002	26000297	Marc Vorpahl	2	shared senior author contribution	shared senior author contribution	-	-	NO
4423002	26000297	Michael Buege	2	contributed equally to this work	contributed equally to this work	-	-	NO
4423002	26000297	Till Koehler	2	contributed equally to this work	contributed equally to this work	-	-	NO
5445715	28572703	A.M.	2	revised the manuscript and supervised the project	revised the manuscript and supervised the project	Wrote the paper	Supervision|Writing - Review & Editing	YES
5445715	28572703	C.C.L.	2	contributed to tem measurement	contributed to tem measurement	Performed the experiments	Investigation	YES
5445715	28572703	K.Y.X.	2	designed the synthesis method and performed the synthesis and characterization|wrote the first version of the manuscript, and all authors discussed the results and contributed to the final version of the manuscript	designed the synthesis method and performed the synthesis and characterization	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5445715	28572703	K.Y.X.	2	designed the synthesis method and performed the synthesis and characterization|wrote the first version of the manuscript, and all authors discussed the results and contributed to the final version of the manuscript	wrote the first version of the manuscript, and all authors discussed the results and contributed to the final version of the manuscript	Wrote the paper	Writing - Original Draft	YES
5445715	28572703	X.B.X.	2	contributed to tem measurement	contributed to tem measurement	Performed the experiments	Investigation	YES
4399838	25880220	AFJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399838	25880220	AFJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399838	25880220	AFJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399838	25880220	AFJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399838	25880220	CF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399838	25880220	CF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399838	25880220	CF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399838	25880220	CF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399838	25880220	CHC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399838	25880220	CHC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399838	25880220	CHC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399838	25880220	CHC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399838	25880220	CHC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399838	25880220	DD	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399838	25880220	DD	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399838	25880220	FB	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399838	25880220	MA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399838	25880220	MA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399838	25880220	MA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399838	25880220	MA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399838	25880220	MA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399838	25880220	TW	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399838	25880220	TW	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5548817	28455834	All authors	2	reviewed the final manuscript	reviewed the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5548817	28455834	Liz Morrell	2	designed and executed the search strategy, carried out the review, and wrote the manuscript|acts as overall guarantor	designed and executed the search strategy, carried out the review, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5548817	28455834	Liz Morrell	2	designed and executed the search strategy, carried out the review, and wrote the manuscript|acts as overall guarantor	acts as overall guarantor	-	-	NO
5548817	28455834	Richard Barker	2	commented on the manuscript	commented on the manuscript	-	-	NO
5548817	28455834	Sarah Wordsworth	2	provided overall guidance, reviewed the extracted data, and commented on the manuscript	provided overall guidance, reviewed the extracted data, and commented on the manuscript	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Resources|Supervision|Writing - Review & Editing	YES
5548817	28455834	Sian Rees	2	commented on the manuscript	commented on the manuscript	-	-	NO
5059965	27729028	ACS	2	help, worked on sequence analysis, and drafted the manuscript|helped in laboratory work and drafted the manuscript	help, worked on sequence analysis, and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5059965	27729028	ACS	2	help, worked on sequence analysis, and drafted the manuscript|helped in laboratory work and drafted the manuscript	helped in laboratory work and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5059965	27729028	JLC	2	helped in the design of the study and to draft the manuscript	helped in the design of the study and to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5059965	27729028	MF	2	participated in all bioinformatic work, and helped to draft the manuscript	participated in all bioinformatic work, and helped to draft the manuscript	Wrote the paper	Formal analysis|Writing - Original Draft	YES
5059965	27729028	MR	2	participated in all bioinformatic work, and helped to draft the manuscript	participated in all bioinformatic work, and helped to draft the manuscript	Wrote the paper	Formal analysis|Writing - Original Draft	YES
5059965	27729028	SBL	2	designed the study and the analysis, wrote the manuscript	designed the study and the analysis, wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5059965	27729028	SG	2	participated in all bioinformatic work, and helped to draft the manuscript	participated in all bioinformatic work, and helped to draft the manuscript	Wrote the paper	Formal analysis|Writing - Original Draft	YES
5450013	28620396	SF	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5450013	28620396	TA	2	designed the study|revised the manuscript critically	designed the study	Conceived and designed the experiments	Methodology	YES
5450013	28620396	TA	2	designed the study|revised the manuscript critically	revised the manuscript critically	Wrote the paper	Writing - Review & Editing	YES
3776301	24044627	All authors	2	contributed to the writing of the manuscript and approved the final version	contributed to the writing of the manuscript and approved the final version	Wrote the paper	Writing - Original Draft	YES
3776301	24044627	JM	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
3776301	24044627	KD	2	collected data and conducted data analysis	collected data and conducted data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3776301	24044627	LM	2	designed the study|collected data and conducted data analysis|drafted the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
3776301	24044627	LM	2	designed the study|collected data and conducted data analysis|drafted the manuscript	collected data and conducted data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3776301	24044627	LM	2	designed the study|collected data and conducted data analysis|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4399839	25880062	HG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399839	25880062	HG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399839	25880062	HG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399839	25880062	NM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399839	25880062	NM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399839	25880062	NM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399839	25880062	SB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399839	25880062	SB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399839	25880062	SB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399839	25880062	SB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5450224	28620398	CU	2	helped in genome-wide association mapping, manuscript preparation, and candidate gene search	helped in genome-wide association mapping, manuscript preparation, and candidate gene search	Wrote the paper	Writing - Original Draft	YES
5450224	28620398	NB	2	helped in the selection of the panel, analysis, and interpretation of the results	helped in the selection of the panel, analysis, and interpretation of the results	Analyzed the data	Formal analysis	YES
5450224	28620398	NS	2	helped in the snp detection and diversity analysis	helped in the snp detection and diversity analysis	Performed the experiments	Investigation	YES
5450224	28620398	PC	2	conceived the idea, designed and supervised the study, prepared the draft of the manuscript, and submitted it	conceived the idea, designed and supervised the study, prepared the draft of the manuscript, and submitted it	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Supervision|Writing - Original Draft	YES
5450224	28620398	SA	2	carried out the phenotyping of the germplasm, analyzed both genotype and phenotype data, and wrote the draft of the manuscript	carried out the phenotyping of the germplasm, analyzed both genotype and phenotype data, and wrote the draft of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5450224	28620398	SK	2	maintained the germplasm in the field and helped in the phenotyping	maintained the germplasm in the field and helped in the phenotyping	Performed the experiments	Investigation	YES
3776924	24047928	AA	2	contributed to data acquisition, critically revising article	contributed to data acquisition, critically revising article	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
3776924	24047928	All authors	2	have read and approved the final article	have read and approved the final article	-	-	NO
3776924	24047928	DKE	2	contributed to concept and design, critically revising article	contributed to concept and design, critically revising article	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
3776924	24047928	EA	2	contributed to data acquisition, critically revising article	contributed to data acquisition, critically revising article	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
3776924	24047928	FD	2	contributed to conception and design, data acquisition, critically revising article	contributed to conception and design, data acquisition, critically revising article	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Investigation|Resources|Writing - Review & Editing	YES
3776924	24047928	FK	2	contributed to data acquisition, critically revising article	contributed to data acquisition, critically revising article	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
3776924	24047928	HIV	2	cohort study group	cohort study group	-	-	NO
3776924	24047928	Joao Paulo	2	cohort study group	cohort study group	-	-	NO
3776924	24047928	KM	2	contributed to conception and design, data acquisition, statistical analysis, data interpretation	contributed to conception and design, data acquisition, statistical analysis, data interpretation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
3776924	24047928	LAR	2	contributed to conception and design, data acquisition, data interpretation and drafting article	contributed to conception and design, data acquisition, data interpretation and drafting article	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Resources|Writing - Original Draft	YES
3776924	24047928	PT	2	contributed to data acquisition, critically revising article	contributed to data acquisition, critically revising article	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
3776924	24047928	RDG	2	contributed to data acquisition, critically revising article	contributed to data acquisition, critically revising article	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
3776924	24047928	TKE	2	contributed to data acquisition, critically revising article	contributed to data acquisition, critically revising article	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
3776924	24047928	The Bissau	2	cohort study group	cohort study group	-	-	NO
3776924	24047928	UO	2	contributed to data acquisition, critically revising article	contributed to data acquisition, critically revising article	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
3776924	24047928	VL	2	contributed to conception and design, data acquisition, interpretation, drafting article	contributed to conception and design, data acquisition, interpretation, drafting article	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Resources|Writing - Original Draft	YES
5062822	27733120	LPX	2	conceived, designed and initiated the project|helped to revise the manuscript	conceived, designed and initiated the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5062822	27733120	LPX	2	conceived, designed and initiated the project|helped to revise the manuscript	helped to revise the manuscript	Wrote the paper	Writing - Review & Editing	YES
5062822	27733120	QP	2	performed experiments and contributed to data analysis and validation	performed experiments and contributed to data analysis and validation	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Validation	YES
5062822	27733120	YC	2	performed experiments and contributed to data analysis and validation	performed experiments and contributed to data analysis and validation	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Validation	YES
5062822	27733120	YCS	2	conceived, designed and initiated the project|prepared materials|performed experiments and contributed to data analysis and validation|drafted the manuscript	conceived, designed and initiated the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5062822	27733120	YCS	2	conceived, designed and initiated the project|prepared materials|performed experiments and contributed to data analysis and validation|drafted the manuscript	prepared materials	Performed the experiments	Investigation	YES
5062822	27733120	YCS	2	conceived, designed and initiated the project|prepared materials|performed experiments and contributed to data analysis and validation|drafted the manuscript	performed experiments and contributed to data analysis and validation	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Validation	YES
5062822	27733120	YCS	2	conceived, designed and initiated the project|prepared materials|performed experiments and contributed to data analysis and validation|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5062822	27733120	YTY	2	performed experiments and contributed to data analysis and validation	performed experiments and contributed to data analysis and validation	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Validation	YES
5062822	27733120	YXQ	2	conceived, designed and initiated the project|helped to revise the manuscript	conceived, designed and initiated the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5062822	27733120	YXQ	2	conceived, designed and initiated the project|helped to revise the manuscript	helped to revise the manuscript	Wrote the paper	Writing - Review & Editing	YES
5062822	27733120	ZQW	2	prepared materials|performed experiments and contributed to data analysis and validation	prepared materials	Performed the experiments	Investigation	YES
5062822	27733120	ZQW	2	prepared materials|performed experiments and contributed to data analysis and validation	performed experiments and contributed to data analysis and validation	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Validation	YES
5548825	28762015	AS	2	assisted with the design of the study and interpretation of the results, and reviewed and modified the manuscript for important intellectual content	assisted with the design of the study and interpretation of the results, and reviewed and modified the manuscript for important intellectual content	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
5548825	28762015	JB	2	initiated and led the study, designed and parameterised the model, conducted the analysis, interpreted the results and drafted the manuscript|acts as the overall guarantor for this work	initiated and led the study, designed and parameterised the model, conducted the analysis, interpreted the results and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5548825	28762015	JB	2	initiated and led the study, designed and parameterised the model, conducted the analysis, interpreted the results and drafted the manuscript|acts as the overall guarantor for this work	acts as the overall guarantor for this work	-	-	NO
5548825	28762015	JCT	2	assisted with the design of the study and interpretation of the results, and reviewed and modified the manuscript for important intellectual content	assisted with the design of the study and interpretation of the results, and reviewed and modified the manuscript for important intellectual content	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
5548825	28762015	PR	2	assisted with the parameterisation of the model and reviewed and modified the manuscript for important intellectual content	assisted with the parameterisation of the model and reviewed and modified the manuscript for important intellectual content	Performed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5548825	28762015	RC	2	assisted with the parameterisation of the model and reviewed and modified the manuscript for important intellectual content	assisted with the parameterisation of the model and reviewed and modified the manuscript for important intellectual content	Performed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5548825	28762015	SJLK	2	assisted with the design of the study and interpretation of the results, and reviewed and modified the manuscript for important intellectual content	assisted with the design of the study and interpretation of the results, and reviewed and modified the manuscript for important intellectual content	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
5548825	28762015	SW	2	assisted with the design of the study and interpretation of the results, and reviewed and modified the manuscript for important intellectual content	assisted with the design of the study and interpretation of the results, and reviewed and modified the manuscript for important intellectual content	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
5445716	28572705	A.L.	2	contributed equally to this work	contributed equally to this work	-	-	NO
5445716	28572705	T.A.G.	2	contributed equally to this work	contributed equally to this work	-	-	NO
4399840	25880982	HH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4399840	25880982	JZ	PLoS5	Literature review	Literature review	-	Formal analysis	YES
4399840	25880982	KW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399840	25880982	KW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399840	25880982	KW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399840	25880982	KW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399840	25880982	LZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399840	25880982	LZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399840	25880982	LZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399840	25880982	QZ	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399840	25880982	XC	PLoS5	Literature review	Literature review	-	Formal analysis	YES
4399840	25880982	YC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399840	25880982	YC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399840	25880982	YC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399840	25880982	ZZ	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5062840	27733115	All authors	PLoS52	contributed to the biological insight, read and approved the final manuscript	contributed to the biological insight, read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5062840	27733115	CS	PLoS52	provided additional test samples	provided additional test samples	Contributed reagents/materials/analysis tools	Resources	YES
5062840	27733115	HC	PLoS52	collected and labeled the data	collected and labeled the data	Performed the experiments	Investigation	YES
5062840	27733115	MB	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5062840	27733115	NA	PLoS52	conceived the study and developed computational methods|wrote the paper	conceived the study and developed computational methods	Conceived and designed the experiments|Performed the experiments	Conceptualization|Formal analysis|Methodology	YES
5062840	27733115	NA	PLoS52	conceived the study and developed computational methods|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3778210	24050252	AI	2	planned the experimental design|were responsible for the patient care and provided clinical information|wrote the article	planned the experimental design	Conceived and designed the experiments	Conceptualization|Methodology	YES
3778210	24050252	AI	2	planned the experimental design|were responsible for the patient care and provided clinical information|wrote the article	were responsible for the patient care and provided clinical information	Performed the experiments	Investigation	YES
3778210	24050252	AI	2	planned the experimental design|were responsible for the patient care and provided clinical information|wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
3778210	24050252	AK-T	2	joined the discussion	joined the discussion	-	-	NO
3778210	24050252	GFG	2	joined the discussion	joined the discussion	-	-	NO
3778210	24050252	HH	2	provided the materials|joined the discussion	provided the materials	Contributed reagents/materials/analysis tools	Resources	YES
3778210	24050252	HH	2	provided the materials|joined the discussion	joined the discussion	-	-	NO
3778210	24050252	HN	2	were responsible for the patient care and provided clinical information	were responsible for the patient care and provided clinical information	Performed the experiments	Investigation	YES
3778210	24050252	MK	2	were responsible for the patient care and provided clinical information	were responsible for the patient care and provided clinical information	Performed the experiments	Investigation	YES
3778210	24050252	NH	2	planned the experimental design|did the experiments|wrote the article|contributed equally to the work	planned the experimental design	Conceived and designed the experiments	Conceptualization|Methodology	YES
3778210	24050252	NH	2	planned the experimental design|did the experiments|wrote the article|contributed equally to the work	did the experiments	Performed the experiments	Investigation	YES
3778210	24050252	NH	2	planned the experimental design|did the experiments|wrote the article|contributed equally to the work	wrote the article	Wrote the paper	Writing - Original Draft	YES
3778210	24050252	NH	2	planned the experimental design|did the experiments|wrote the article|contributed equally to the work	contributed equally to the work	-	-	NO
3778210	24050252	NK	2	provided the materials	provided the materials	Contributed reagents/materials/analysis tools	Resources	YES
3778210	24050252	PT	2	planned the experimental design|did the experiments|wrote the article|contributed equally to the work	planned the experimental design	Conceived and designed the experiments	Conceptualization|Methodology	YES
3778210	24050252	PT	2	planned the experimental design|did the experiments|wrote the article|contributed equally to the work	did the experiments	Performed the experiments	Investigation	YES
3778210	24050252	PT	2	planned the experimental design|did the experiments|wrote the article|contributed equally to the work	wrote the article	Wrote the paper	Writing - Original Draft	YES
3778210	24050252	PT	2	planned the experimental design|did the experiments|wrote the article|contributed equally to the work	contributed equally to the work	-	-	NO
3778210	24050252	TF	2	were responsible for the patient care and provided clinical information	were responsible for the patient care and provided clinical information	Performed the experiments	Investigation	YES
3778210	24050252	TK	2	were responsible for the patient care and provided clinical information	were responsible for the patient care and provided clinical information	Performed the experiments	Investigation	YES
3778210	24050252	ZM	2	provided the materials|joined the discussion	provided the materials	Contributed reagents/materials/analysis tools	Resources	YES
3778210	24050252	ZM	2	provided the materials|joined the discussion	joined the discussion	-	-	NO
5450380	28620397	CC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Provided expertise and editing	Analyzed the data	Analyzed the data	Formal analysis	YES
5450380	28620397	CC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Provided expertise and editing	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5450380	28620397	CC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Provided expertise and editing	Provided expertise and editing	Wrote the paper	Writing - Review & Editing	YES
5450380	28620397	CL	PLoS5	Contributed reagents/materials/analysis tools|Provided expertise and editing	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5450380	28620397	CL	PLoS5	Contributed reagents/materials/analysis tools|Provided expertise and editing	Provided expertise and editing	Wrote the paper	Writing - Review & Editing	YES
5450380	28620397	CM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Provided expertise and editing	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5450380	28620397	CM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Provided expertise and editing	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5450380	28620397	CM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Provided expertise and editing	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5450380	28620397	CM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Provided expertise and editing	Provided expertise and editing	Wrote the paper	Writing - Review & Editing	YES
5450380	28620397	LP	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
5450380	28620397	LP	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5450380	28620397	PS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5450380	28620397	PS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
5450380	28620397	PS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5450380	28620397	PS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5450380	28620397	TC	PLoS5	Performed the experiments|Analyzed the data|Provided expertise and editing	Performed the experiments	Performed the experiments	Investigation	YES
5450380	28620397	TC	PLoS5	Performed the experiments|Analyzed the data|Provided expertise and editing	Analyzed the data	Analyzed the data	Formal analysis	YES
5450380	28620397	TC	PLoS5	Performed the experiments|Analyzed the data|Provided expertise and editing	Provided expertise and editing	Wrote the paper	Writing - Review & Editing	YES
4399841	25880223	GCE	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Reviewed and approved the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4399841	25880223	GCE	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Reviewed and approved the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4399841	25880223	GCE	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Reviewed and approved the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399841	25880223	GCE	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Reviewed and approved the manuscript	Reviewed and approved the manuscript	Wrote the paper	Writing - Review & Editing	YES
4399841	25880223	JRR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399841	25880223	JRR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399841	25880223	JRR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399841	25880223	JRR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399841	25880223	MSH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Reviewed and approved the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4399841	25880223	MSH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Reviewed and approved the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4399841	25880223	MSH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Reviewed and approved the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399841	25880223	MSH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Reviewed and approved the manuscript	Reviewed and approved the manuscript	Wrote the paper	Writing - Review & Editing	YES
4399841	25880223	TT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399841	25880223	TT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399841	25880223	TT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399841	25880223	TT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4423012	25984530	Margita Marton	2	are equally contributing authors	are equally contributing authors	-	-	NO
4423012	25984530	Marianna Holczer	2	are equally contributing authors	are equally contributing authors	-	-	NO
5445717	28572702	F. Palazon	2	contributed equally to this work	contributed equally to this work	-	-	NO
5445717	28572702	G. Almeida	2	contributed equally to this work	contributed equally to this work	-	-	NO
3789211	24088395	ML	2	with contributions from all authors	with contributions from all authors	-	-	NO
5563360	28342114	All authors	2	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5563360	28342114	Howard Thom	2	conducted the model comparison|drafted the paper and all authors critically reviewed and agreed to it as submitted	conducted the model comparison	Performed the experiments	Investigation|Methodology	YES
5563360	28342114	Howard Thom	2	conducted the model comparison|drafted the paper and all authors critically reviewed and agreed to it as submitted	drafted the paper and all authors critically reviewed and agreed to it as submitted	Wrote the paper	Writing - Original Draft	YES
5450411	28620409	AF	2	conceived and planned the experiment|set up and monitored the canopy gas exchange system|performed the experimental work, data analysis and drafted the manuscript	conceived and planned the experiment	Conceived and designed the experiments	Conceptualization	YES
5450411	28620409	AF	2	conceived and planned the experiment|set up and monitored the canopy gas exchange system|performed the experimental work, data analysis and drafted the manuscript	set up and monitored the canopy gas exchange system	Performed the experiments	Methodology|Supervision	YES
5450411	28620409	AF	2	conceived and planned the experiment|set up and monitored the canopy gas exchange system|performed the experimental work, data analysis and drafted the manuscript	performed the experimental work, data analysis and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5450411	28620409	AM	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5450411	28620409	All the authors	2	have read and approved the final manuscript	have read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5450411	28620409	EM	2	set up and monitored the canopy gas exchange system	set up and monitored the canopy gas exchange system	Performed the experiments	Methodology|Supervision	YES
5450411	28620409	SA	2	conceived and planned the experiment|revised the manuscript|supervised the research	conceived and planned the experiment	Conceived and designed the experiments	Conceptualization	YES
5450411	28620409	SA	2	conceived and planned the experiment|revised the manuscript|supervised the research	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5450411	28620409	SA	2	conceived and planned the experiment|revised the manuscript|supervised the research	supervised the research	-	Supervision	YES
5062844	27733118	CHG	2	contributed with valuable discussions	contributed with valuable discussions	-	-	NO
5062844	27733118	EHW	2	helped to carried out experiments and analyzed data	helped to carried out experiments and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5062844	27733118	LCL	2	provided reagents	provided reagents	Contributed reagents/materials/analysis tools	Resources	YES
5062844	27733118	LQH	2	helped to carried out experiments and analyzed data	helped to carried out experiments and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5062844	27733118	LZ	2	helped to carried out experiments and analyzed data	helped to carried out experiments and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5062844	27733118	MC	2	conceived and designed experiments, and edited the manuscript	conceived and designed experiments, and edited the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
5062844	27733118	MH	2	participated in the study design and helped to draft the manuscript	participated in the study design and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5062844	27733118	YBZ	2	provided reagents	provided reagents	Contributed reagents/materials/analysis tools	Resources	YES
5062844	27733118	YZM	2	contributed with valuable discussions	contributed with valuable discussions	-	-	NO
5062844	27733118	ZC	2	helped to carried out experiments and analyzed data	helped to carried out experiments and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5062844	27733118	ZSX	2	provided reagents	provided reagents	Contributed reagents/materials/analysis tools	Resources	YES
4399842	25879443	AR	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4399842	25879443	JFC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399842	25879443	JFC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399842	25879443	JFC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399842	25879443	JFC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399842	25879443	LF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399842	25879443	LF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399842	25879443	LF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399842	25879443	LF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399842	25879443	LT	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4399842	25879443	LT	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4399842	25879443	RB	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399842	25879443	SMR	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399842	25879443	SMR	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399842	25879443	SMR	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399842	25879443	ZB	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399842	25879443	ZB	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3790908	24093951	AD	PLoS5	Designed the sampling method|Analyzed the data	Designed the sampling method	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3790908	24093951	AD	PLoS5	Designed the sampling method|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
3790908	24093951	DAD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
3790908	24093951	DAD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
3790908	24093951	DAD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3790908	24093951	DI	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
3790908	24093951	EB	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
3790908	24093951	HS	PLoS5	Designed the sampling method|Conceived and designed the experiments|Analyzed the data	Designed the sampling method	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3790908	24093951	HS	PLoS5	Designed the sampling method|Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
3790908	24093951	HS	PLoS5	Designed the sampling method|Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
3790908	24093951	IZ	PLoS5	Identified recent infections|Analyzed the data	Identified recent infections	Performed the experiments	Investigation	YES
3790908	24093951	IZ	PLoS5	Identified recent infections|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
3790908	24093951	MBB	PLoS5	Identified recent infections|Analyzed the data	Identified recent infections	Performed the experiments	Investigation	YES
3790908	24093951	MBB	PLoS5	Identified recent infections|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
3790908	24093951	MV	PLoS5	Designed the sampling method|Analyzed the data	Designed the sampling method	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3790908	24093951	MV	PLoS5	Designed the sampling method|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
3790908	24093951	NRR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
3790908	24093951	NRR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
3790908	24093951	NRR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
3790908	24093951	NRR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399843	25880869	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399843	25880869	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399843	25880869	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399843	25880869	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399843	25880869	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399843	25880869	AR	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399843	25880869	AR	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399843	25880869	AR	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399843	25880869	AV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399843	25880869	AV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399843	25880869	AV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399843	25880869	AV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399843	25880869	AV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399843	25880869	EM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399843	25880869	EM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399843	25880869	EM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399843	25880869	EM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399843	25880869	FG	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399843	25880869	FG	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399843	25880869	FG	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399843	25880869	GV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399843	25880869	GV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399843	25880869	GV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399843	25880869	GV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399843	25880869	GV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5450422	28620405	FL	PLoS52	wrote the computer codes|analyzed the data|wrote the manuscript	wrote the computer codes	Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Software|Writing - Original Draft	YES
5450422	28620405	FL	PLoS52	wrote the computer codes|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5450422	28620405	FL	PLoS52	wrote the computer codes|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5450422	28620405	JP	PLoS52	performed experiments|analyzed the data|wrote the manuscript	performed experiments	Performed the experiments	Investigation	YES
5450422	28620405	JP	PLoS52	performed experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5450422	28620405	JP	PLoS52	performed experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5450422	28620405	RC	PLoS52	planned and designed the research|analyzed the data|wrote the manuscript	planned and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5450422	28620405	RC	PLoS52	planned and designed the research|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5450422	28620405	RC	PLoS52	planned and designed the research|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5450422	28620405	The authors	PLoS52	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	Performed the experiments	Investigation	YES
3794079	24107652	Alan Whiteside	2	provided expert counsel on the major concerns of the manuscript and contributed substantial intellectual review of content for the duration of the article preparation	provided expert counsel on the major concerns of the manuscript and contributed substantial intellectual review of content for the duration of the article preparation	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3794079	24107652	MPH	2	was a co-principal investigator on the project, and as such formulated the research design, designed the research instruments, managed data collection in the field, executed data analysis and drafted this article	was a co-principal investigator on the project, and as such formulated the research design, designed the research instruments, managed data collection in the field, executed data analysis and drafted this article	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Data curation|Formal analysis|Funding acquisition|Investigation|Methodology|Project administration|Writing - Original Draft	YES
3794079	24107652	PhD	2	was a co-principal investigator on the project, and as such formulated the research design, designed the research instruments, managed data collection in the field, executed data analysis and drafted this article	was a co-principal investigator on the project, and as such formulated the research design, designed the research instruments, managed data collection in the field, executed data analysis and drafted this article	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Data curation|Formal analysis|Funding acquisition|Investigation|Methodology|Project administration|Writing - Original Draft	YES
3794079	24107652	Robin Root	2	was a co-principal investigator on the project, and as such formulated the research design, designed the research instruments, managed data collection in the field, executed data analysis and drafted this article	was a co-principal investigator on the project, and as such formulated the research design, designed the research instruments, managed data collection in the field, executed data analysis and drafted this article	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Data curation|Formal analysis|Funding acquisition|Investigation|Methodology|Project administration|Writing - Original Draft	YES
5062943	27733113	BMN	2	participated in the data analysis and draft preparation	participated in the data analysis and draft preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5062943	27733113	CBW	2	co-concieved the study, participated in the design and draft preparation	co-concieved the study, participated in the design and draft preparation	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5062943	27733113	DRR	2	co-concieved the study, participated in the design, metabolic analysis, and draft preparation	co-concieved the study, participated in the design, metabolic analysis, and draft preparation	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5062943	27733113	IH	2	participated in the design and performance of the storage experiment	participated in the design and performance of the storage experiment	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5062943	27733113	JJG	2	participated in the rna seq and data analysis	participated in the rna seq and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5062943	27733113	JPM	2	co-concieved the study, participated in the design and performed the storage experiment and fruit quality analysis	co-concieved the study, participated in the design and performed the storage experiment and fruit quality analysis	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5062943	27733113	JWJ	2	co-concieved the study, participated in the design, and draft preparation	co-concieved the study, participated in the design, and draft preparation	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5062943	27733113	MLATMH	2	participated in the data analysis and draft preparation	participated in the data analysis and draft preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5062943	27733113	NEG	2	participated in the design and performed the rna seq analysis	participated in the design and performed the rna seq analysis	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5062943	27733113	NLS	2	participated in the metabolic profiling portion and data analysis	participated in the metabolic profiling portion and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5062943	27733113	RJS	2	co-concieved the study, participated in the design, and draft preparation	co-concieved the study, participated in the design, and draft preparation	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5062943	27733113	RSL	2	participated in the design, performed the storage experiment, performed the metabolic profiling portions, and drafted the manuscript	participated in the design, performed the storage experiment, performed the metabolic profiling portions, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
4399844	25881158	AE	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399844	25881158	AE	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399844	25881158	AE	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399844	25881158	BB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399844	25881158	BB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399844	25881158	BB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399844	25881158	BB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399844	25881158	BB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399844	25881158	DG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399844	25881158	DG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399844	25881158	DG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399844	25881158	PR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399844	25881158	PR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399844	25881158	PR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399844	25881158	PR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399844	25881158	PR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399844	25881158	PS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399844	25881158	PS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399844	25881158	PS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399844	25881158	PS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399844	25881158	PS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5840199	29222670	All authors	2	commented on the manuscript and approved the final version	commented on the manuscript and approved the final version	-	-	NO
5840199	29222670	CN	2	all formed part of the erg report that this paper describes|drafted the manuscript	all formed part of the erg report that this paper describes	-	-	NO
5840199	29222670	CN	2	all formed part of the erg report that this paper describes|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5840199	29222670	EL	2	all formed part of the erg report that this paper describes	all formed part of the erg report that this paper describes	-	-	NO
5840199	29222670	HM	2	all formed part of the erg report that this paper describes|drafted the manuscript	all formed part of the erg report that this paper describes	-	-	NO
5840199	29222670	HM	2	all formed part of the erg report that this paper describes|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5840199	29222670	JC	2	all formed part of the erg report that this paper describes	all formed part of the erg report that this paper describes	-	-	NO
5840199	29222670	JM	2	all formed part of the erg report that this paper describes	all formed part of the erg report that this paper describes	-	-	NO
5840199	29222670	MC	2	all formed part of the erg report that this paper describes|drafted the manuscript	all formed part of the erg report that this paper describes	-	-	NO
5840199	29222670	MC	2	all formed part of the erg report that this paper describes|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5840199	29222670	RW	2	all formed part of the erg report that this paper describes	all formed part of the erg report that this paper describes	-	-	NO
5840199	29222670	TM	2	all formed part of the erg report that this paper describes	all formed part of the erg report that this paper describes	-	-	NO
3796216	24119708	AM	2	designed the study, collected and analyzed the data, and reviewed the article	designed the study, collected and analyzed the data, and reviewed the article	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Review & Editing	YES
3796216	24119708	All authors	2	read and approved the final draft of the article	read and approved the final draft of the article	Wrote the paper	Writing - Original Draft	YES
3796216	24119708	EJM	2	designed the study, oversaw its conduct, data analysis, and interpretation and drafted the original article and reviewed the final draft	designed the study, oversaw its conduct, data analysis, and interpretation and drafted the original article and reviewed the final draft	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Supervision|Writing - Original Draft	YES
3796216	24119708	GHL	2	assisted in the drafting of the article, data analysis, interpretation and review of the article	assisted in the drafting of the article, data analysis, interpretation and review of the article	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
4399875	25879570	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399875	25879570	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399875	25879570	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399875	25879570	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399875	25879570	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399875	25879570	DE	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399875	25879570	DE	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399875	25879570	DE	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399875	25879570	IJ	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399875	25879570	IJ	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399875	25879570	MO	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4399875	25879570	OO	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399875	25879570	OO	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399875	25879570	SS	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399875	25879570	SS	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399875	25879570	ZK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399875	25879570	ZK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399875	25879570	ZK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399875	25879570	ZK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399875	25879570	ZK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5450510	28620410	CD	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5450510	28620410	CS	PLoS52	performed the experiments|analyzed the data|contributed reagents/materials/analysis tools|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5450510	28620410	CS	PLoS52	performed the experiments|analyzed the data|contributed reagents/materials/analysis tools|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5450510	28620410	CS	PLoS52	performed the experiments|analyzed the data|contributed reagents/materials/analysis tools|wrote the paper	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5450510	28620410	CS	PLoS52	performed the experiments|analyzed the data|contributed reagents/materials/analysis tools|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5450510	28620410	CX	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5450510	28620410	JW	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5450510	28620410	LP	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5450510	28620410	QS	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5450510	28620410	XS	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5450510	28620410	YK	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5450510	28620410	YX	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5906516	29445964	All	2	authours contributed to interpretation of the analysis and editing and revising the manuscript	authours contributed to interpretation of the analysis and editing and revising the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5906516	29445964	DD	2	contributed to the study rationale and design	contributed to the study rationale and design	Conceived and designed the experiments	Methodology	YES
5906516	29445964	EK	2	carried out the analysis of the data and prepared the draft of the manuscript	carried out the analysis of the data and prepared the draft of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5906516	29445964	SD	2	contributed to the study rationale and design	contributed to the study rationale and design	Conceived and designed the experiments	Methodology	YES
5503176	28706347	All authors	2	have given approval to the final version of the manuscript	have given approval to the final version of the manuscript	-	-	NO
4399876	25879759	GQL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399876	25879759	GQL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399876	25879759	GQL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399876	25879759	JWS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399876	25879759	LJL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4399876	25879759	PH	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399876	25879759	PH	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399876	25879759	QZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399876	25879759	QZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399876	25879759	QZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399876	25879759	QZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399876	25879759	QZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399876	25879759	WZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399876	25879759	WZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399876	25879759	WZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399876	25879759	XBW	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4426654	26000291	De-Wang Wang	2	contributed equally	contributed equally	-	-	NO
4426654	26000291	Yu-Jiao Guo	2	contributed equally	contributed equally	-	-	NO
5450565	28620400	CT	2	helped in devising the rs methodology, and in pre-processing of the satellite data, as well as some of the mapping work	helped in devising the rs methodology, and in pre-processing of the satellite data, as well as some of the mapping work	Performed the experiments|Analyzed the data	Data curation|Methodology	YES
5450565	28620400	HN	2	helped in refining conceptualization of the study, supervised the rs and field work, and co-wrote the manuscript	helped in refining conceptualization of the study, supervised the rs and field work, and co-wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Supervision|Writing - Original Draft	YES
5450565	28620400	MA	2	helped in devising the rs methodology, and in pre-processing of the satellite data, as well as some of the mapping work	helped in devising the rs methodology, and in pre-processing of the satellite data, as well as some of the mapping work	Performed the experiments|Analyzed the data	Data curation|Methodology	YES
5450565	28620400	MN	2	conceptualized part of the study, did field work	conceptualized part of the study, did field work	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5450565	28620400	PB	2	helped in conceptualization, facilitation and supervision of the rs work	helped in conceptualization, facilitation and supervision of the rs work	Conceived and designed the experiments	Conceptualization|Supervision	YES
5450565	28620400	RS	2	statistical analysis, and wrote the manuscript	statistical analysis, and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5069875	27756228	AG	PLoS5	Performed the in vitro validation experiments	Performed the in vitro validation experiments	Performed the experiments	Investigation|Validation	YES
5069875	27756228	ALL	PLoS5	Manuscript	Manuscript	-	-	NO
5069875	27756228	BLF	PLoS5	Conceived and designed the study|Wrote the paper	Conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5069875	27756228	BLF	PLoS5	Conceived and designed the study|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5069875	27756228	CW	PLoS5	Performed gene expression studies in tumors|Analyses	Performed gene expression studies in tumors	Performed the experiments	Investigation	YES
5069875	27756228	CW	PLoS5	Performed gene expression studies in tumors|Analyses	Analyses	Analyzed the data	Formal analysis	YES
5069875	27756228	ELG	PLoS5	Performed gene expression studies in tumors	Performed gene expression studies in tumors	Performed the experiments	Investigation	YES
5069875	27756228	GK	PLoS5	Performed gene expression studies in tumors	Performed gene expression studies in tumors	Performed the experiments	Investigation	YES
5069875	27756228	HP	PLoS5	Performed the in vitro validation experiments|Wrote the paper	Performed the in vitro validation experiments	Performed the experiments	Investigation|Validation	YES
5069875	27756228	HP	PLoS5	Performed the in vitro validation experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5069875	27756228	RR	PLoS5	Conceived and designed the study|Analyses|Wrote the paper	Conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5069875	27756228	RR	PLoS5	Conceived and designed the study|Analyses|Wrote the paper	Analyses	Analyzed the data	Formal analysis	YES
5069875	27756228	RR	PLoS5	Conceived and designed the study|Analyses|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5069875	27756228	SH	PLoS5	Performed the in vitro validation experiments|Wrote the paper	Performed the in vitro validation experiments	Performed the experiments	Investigation|Validation	YES
5069875	27756228	SH	PLoS5	Performed the in vitro validation experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6021473	29679317	All authors	2	critically reviewed the manuscript and approved its final content	critically reviewed the manuscript and approved its final content	Wrote the paper	Writing - Review & Editing	YES
6021473	29679317	BL	2	had the original idea of the tutorial|conducted the statistical analysis, wrote the first draft of the manuscript and developed the implementation code in stata|acts as the overall guarantor	had the original idea of the tutorial	Conceived and designed the experiments	Conceptualization	YES
6021473	29679317	BL	2	had the original idea of the tutorial|conducted the statistical analysis, wrote the first draft of the manuscript and developed the implementation code in stata|acts as the overall guarantor	conducted the statistical analysis, wrote the first draft of the manuscript and developed the implementation code in stata	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Software|Writing - Original Draft	YES
6021473	29679317	BL	2	had the original idea of the tutorial|conducted the statistical analysis, wrote the first draft of the manuscript and developed the implementation code in stata|acts as the overall guarantor	acts as the overall guarantor	-	-	NO
6021473	29679317	JC	2	had the original idea of the tutorial	had the original idea of the tutorial	Conceived and designed the experiments	Conceptualization	YES
6021473	29679317	MG	2	had the original idea of the tutorial	had the original idea of the tutorial	Conceived and designed the experiments	Conceptualization	YES
3827457	24225350	CB	2	critically read and revised subsequent versions	critically read and revised subsequent versions	Wrote the paper	Writing - Review & Editing	YES
3827457	24225350	MM	2	wrote the first draft|critically read and revised subsequent versions	wrote the first draft	Wrote the paper	Writing - Original Draft	YES
3827457	24225350	MM	2	wrote the first draft|critically read and revised subsequent versions	critically read and revised subsequent versions	Wrote the paper	Writing - Review & Editing	YES
4399877	25879453	AA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399877	25879453	AA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399877	25879453	AA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399877	25879453	AA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399877	25879453	AK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399877	25879453	AK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399877	25879453	AK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399877	25879453	AK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399877	25879453	AN	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4399877	25879453	ARN	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4399877	25879453	CA	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4399877	25879453	CA	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399877	25879453	CM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399877	25879453	CM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399877	25879453	CM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399877	25879453	CM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399877	25879453	CM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399877	25879453	LA	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399877	25879453	LA	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4399877	25879453	LA	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399877	25879453	MA	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4399877	25879453	NS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4399877	25879453	PNA	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4399877	25879453	PSSR	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399877	25879453	PSSR	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399877	25879453	PSSR	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399877	25879453	SK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399877	25879453	SK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399877	25879453	SK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399877	25879453	SK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399877	25879453	SS	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399877	25879453	SS	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2698421	19543548	GRW	1	Study design|Data analysis|Manuscript preparation	Study design	Conceived and designed the experiments	Methodology	YES
2698421	19543548	GRW	1	Study design|Data analysis|Manuscript preparation	Data analysis	Analyzed the data	Formal analysis	YES
2698421	19543548	GRW	1	Study design|Data analysis|Manuscript preparation	Manuscript preparation	Wrote the paper	Writing - Original Draft	YES
2698421	19543548	IM	1	Study design|Data collection|Data analysis|Manuscript preparation	Study design	Conceived and designed the experiments	Methodology	YES
2698421	19543548	IM	1	Study design|Data collection|Data analysis|Manuscript preparation	Data collection	Performed the experiments	Investigation	YES
2698421	19543548	IM	1	Study design|Data collection|Data analysis|Manuscript preparation	Data analysis	Analyzed the data	Formal analysis	YES
2698421	19543548	IM	1	Study design|Data collection|Data analysis|Manuscript preparation	Manuscript preparation	Wrote the paper	Writing - Original Draft	YES
2698421	19543548	JM	1	Study design|Data analysis|Manuscript preparation	Study design	Conceived and designed the experiments	Methodology	YES
2698421	19543548	JM	1	Study design|Data analysis|Manuscript preparation	Data analysis	Analyzed the data	Formal analysis	YES
2698421	19543548	JM	1	Study design|Data analysis|Manuscript preparation	Manuscript preparation	Wrote the paper	Writing - Original Draft	YES
2698421	19543548	RJ	1	Data analysis|Manuscript preparation	Data analysis	Analyzed the data	Formal analysis	YES
2698421	19543548	RJ	1	Data analysis|Manuscript preparation	Manuscript preparation	Wrote the paper	Writing - Original Draft	YES
6132447	29785689	James Buchanan	2	contributed to the design of the study and the interpretation of the results, and drafted the manuscript	contributed to the design of the study and the interpretation of the results, and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
6132447	29785689	Jose Leal	2	initiated, designed and led the study, contributed to the analysis and interpretation of the results, and drafted the manuscript|acts as the overall guarantor for this work	initiated, designed and led the study, contributed to the analysis and interpretation of the results, and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
6132447	29785689	Jose Leal	2	initiated, designed and led the study, contributed to the analysis and interpretation of the results, and drafted the manuscript|acts as the overall guarantor for this work	acts as the overall guarantor for this work	-	-	NO
6132447	29785689	Stefania Manetti	2	conducted the analysis and contributed to the interpretation of the results	conducted the analysis and contributed to the interpretation of the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5070092	27756226	HD	2	raised the specimens, collected the fin clips and editing of the manuscript	raised the specimens, collected the fin clips and editing of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5070092	27756226	J-FB	2	raised the specimens and collected the fin clips	raised the specimens and collected the fin clips	Performed the experiments	Investigation	YES
5070092	27756226	MAC	2	was involved in computational analyses and editing of the manuscript	was involved in computational analyses and editing of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5070092	27756226	TDK	2	helped conceive the study, constructed the pooled dna libraries, guided the analysis and helped draft the manuscript	helped conceive the study, constructed the pooled dna libraries, guided the analysis and helped draft the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Supervision|Writing - Original Draft	YES
5070092	27756226	WJG	2	helped conceive the study and was involved in dna extraction, dna quantification, computational analyses and drafting of the manuscript	helped conceive the study and was involved in dna extraction, dna quantification, computational analyses and drafting of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
5452422	28620395	AG	2	designed and performed the experiments, analyzed the data and wrote the manuscript	designed and performed the experiments, analyzed the data and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
2705066	19587795	Both authors	2	have written several drafts and approved the final manuscript	have written several drafts and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
2705066	19587795	EvT	2	was a joint supervisor of this research project at the university of aberdeen and participated in most stages of the study	was a joint supervisor of this research project at the university of aberdeen and participated in most stages of the study	-	Supervision	YES
2705066	19587795	PK	2	contributed to the questionnaire design, carried out the data collection, input and analysis for this study as part of her msc in health services and public health research	contributed to the questionnaire design, carried out the data collection, input and analysis for this study as part of her msc in health services and public health research	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Methodology|Resources	YES
3830054	24241957	All authors	2	contributed to editing and have approved the manuscript	contributed to editing and have approved the manuscript	Wrote the paper	Writing - Review & Editing	YES
3830054	24241957	DJ	2	originally conceptualized the study and wrote the study protocol|conducted the data analysis|wrote the first draft and serves as corresponding author for the manuscript	originally conceptualized the study and wrote the study protocol	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
3830054	24241957	DJ	2	originally conceptualized the study and wrote the study protocol|conducted the data analysis|wrote the first draft and serves as corresponding author for the manuscript	conducted the data analysis	Analyzed the data	Formal analysis	YES
3830054	24241957	DJ	2	originally conceptualized the study and wrote the study protocol|conducted the data analysis|wrote the first draft and serves as corresponding author for the manuscript	wrote the first draft and serves as corresponding author for the manuscript	Wrote the paper	Writing - Original Draft	YES
3830054	24241957	HT	2	managed the fieldwork and supervised conduct of the study	managed the fieldwork and supervised conduct of the study	Performed the experiments	Investigation|Project administration|Supervision	YES
3830054	24241957	MP	2	conducted the laboratory analysis	conducted the laboratory analysis	Performed the experiments	Investigation	YES
3830054	24241957	RN	2	managed the fieldwork and supervised conduct of the study|conducted the data analysis	managed the fieldwork and supervised conduct of the study	Performed the experiments	Investigation|Project administration|Supervision	YES
3830054	24241957	RN	2	managed the fieldwork and supervised conduct of the study|conducted the data analysis	conducted the data analysis	Analyzed the data	Formal analysis	YES
3830054	24241957	SM	2	conducted the laboratory analysis	conducted the laboratory analysis	Performed the experiments	Investigation	YES
3830054	24241957	TD	2	originally conceptualized the study and wrote the study protocol|was overall principal investigator of the study	originally conceptualized the study and wrote the study protocol	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
3830054	24241957	TD	2	originally conceptualized the study and wrote the study protocol|was overall principal investigator of the study	was overall principal investigator of the study	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
3830054	24241957	WZ	2	managed the fieldwork and supervised conduct of the study	managed the fieldwork and supervised conduct of the study	Performed the experiments	Investigation|Project administration|Supervision	YES
6380198	30328051	AB	2	provided critical appraisal of the clinical and economic evidence	provided critical appraisal of the clinical and economic evidence	-	-	NO
6380198	30328051	All authors	2	read and commented on draft versions of this paper	read and commented on draft versions of this paper	Wrote the paper	Writing - Original Draft	YES
6380198	30328051	EK	2	provided critical appraisal of the companys search strategies	provided critical appraisal of the companys search strategies	-	-	NO
6380198	30328051	IP	2	provided clinical advice and critical appraisal of the report	provided clinical advice and critical appraisal of the report	-	-	NO
6380198	30328051	JG	2	provided critical appraisal of the clinical evidence	provided critical appraisal of the clinical evidence	-	-	NO
6380198	30328051	JM	2	provided critical appraisal of the economic evidence/model|provided critical appraisal of the company submission	provided critical appraisal of the economic evidence/model	Performed the experiments	Methodology	YES
6380198	30328051	JM	2	provided critical appraisal of the economic evidence/model|provided critical appraisal of the company submission	provided critical appraisal of the company submission	-	-	NO
6380198	30328051	RD	2	provided critical appraisal of the clinical evidence and supervised the production of the final report	provided critical appraisal of the clinical evidence and supervised the production of the final report	-	Supervision	YES
6380198	30328051	SB	2	provided critical appraisal of the economic evidence	provided critical appraisal of the economic evidence	-	-	NO
6380198	30328051	SN	2	provided critical appraisal of the statistical evidence	provided critical appraisal of the statistical evidence	Analyzed the data	Formal analysis	YES
6380198	30328051	TL	2	drafted versions of this paper	drafted versions of this paper	Wrote the paper	Writing - Original Draft	YES
4399878	25880668	AS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4399878	25880668	AS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4399878	25880668	CKP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399878	25880668	CKP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4399878	25880668	CKP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4399878	25880668	CKP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399878	25880668	CN	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4399878	25880668	CN	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4399878	25880668	JB	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4399878	25880668	JB	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399878	25880668	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399878	25880668	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4399878	25880668	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399878	25880668	MMP	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399878	25880668	MMP	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4399878	25880668	MMP	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399878	25880668	NCH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399878	25880668	NCH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399878	25880668	NCH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399878	25880668	NCH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399878	25880668	RC	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399878	25880668	RC	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4399878	25880668	RC	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399878	25880668	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399878	25880668	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399878	25880668	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399878	25880668	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399878	25880668	VW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399878	25880668	VW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4399878	25880668	VW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399878	25880668	XM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399878	25880668	XM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4399878	25880668	XM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4399878	25880668	XM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5454049	28626465	All authors	2	contributed to the writing	contributed to the writing	Wrote the paper	-	YES
5454049	28626465	KM	2	designed the experiments|performed the experiments and analyzed the data	designed the experiments	Conceived and designed the experiments	Methodology	YES
5454049	28626465	KM	2	designed the experiments|performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5454049	28626465	KR	2	designed the experiments|performed the experiments and analyzed the data	designed the experiments	Conceived and designed the experiments	Methodology	YES
5454049	28626465	KR	2	designed the experiments|performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5454049	28626465	SR	2	designed the experiments|supervised the experiments|conceived the project	designed the experiments	Conceived and designed the experiments	Methodology	YES
5454049	28626465	SR	2	designed the experiments|supervised the experiments|conceived the project	supervised the experiments	-	Supervision	YES
5454049	28626465	SR	2	designed the experiments|supervised the experiments|conceived the project	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5454049	28626465	SZ	2	designed the experiments|performed the experiments and analyzed the data	designed the experiments	Conceived and designed the experiments	Methodology	YES
5454049	28626465	SZ	2	designed the experiments|performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5454049	28626465	Y-MB	2	designed the experiments|supervised the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5454049	28626465	Y-MB	2	designed the experiments|supervised the experiments	supervised the experiments	-	Supervision	YES
5070125	27756225	AL	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5070125	27756225	JCG	PLoS52	conceived and designed the experiment|performed the experiments	conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5070125	27756225	JCG	PLoS52	conceived and designed the experiment|performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5070125	27756225	JM	PLoS52	analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
5070125	27756225	PYR	PLoS52	conceived and designed the experiment|analysed the data|wrote the paper	conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5070125	27756225	PYR	PLoS52	conceived and designed the experiment|analysed the data|wrote the paper	analysed the data	Analyzed the data	Formal analysis	YES
5070125	27756225	PYR	PLoS52	conceived and designed the experiment|analysed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399880	25879541	GRL	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399880	25879541	GRL	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4399880	25879541	JD	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399880	25879541	JD	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399880	25879541	JPH	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399880	25879541	JPH	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399880	25879541	XHY	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399880	25879541	XHY	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399880	25879541	XHY	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5627989	28989232	All authors	2	have given approval to the final version of the manuscript	have given approval to the final version of the manuscript	-	-	NO
3833102	24242260	All authors	2	have read and approved the final manuscript	have read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
3833102	24242260	Literature Review Process	2	and editing	and editing	Wrote the paper	Writing - Review & Editing	YES
4399882	25881302	GL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Acquired data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399882	25881302	GL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Acquired data	Performed the experiments	Performed the experiments	Investigation	YES
4399882	25881302	GL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Acquired data	Analyzed the data	Analyzed the data	Formal analysis	YES
4399882	25881302	GL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Acquired data	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399882	25881302	GL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Acquired data	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399882	25881302	GL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Acquired data	Acquired data	Performed the experiments	Investigation	YES
4399882	25881302	LG	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Acquired data	Performed the experiments	Performed the experiments	Investigation	YES
4399882	25881302	LG	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Acquired data	Analyzed the data	Analyzed the data	Formal analysis	YES
4399882	25881302	LG	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Acquired data	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399882	25881302	LG	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Acquired data	Acquired data	Performed the experiments	Investigation	YES
4399882	25881302	LLP	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Acquired data	Performed the experiments	Performed the experiments	Investigation	YES
4399882	25881302	LLP	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Acquired data	Analyzed the data	Analyzed the data	Formal analysis	YES
4399882	25881302	LLP	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Acquired data	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399882	25881302	LLP	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Acquired data	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399882	25881302	LLP	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Acquired data	Acquired data	Performed the experiments	Investigation	YES
4399882	25881302	NB	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Acquired data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399882	25881302	NB	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Acquired data	Performed the experiments	Performed the experiments	Investigation	YES
4399882	25881302	NB	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Acquired data	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399882	25881302	NB	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Acquired data	Acquired data	Performed the experiments	Investigation	YES
4399882	25881302	OC	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Acquired data	Performed the experiments	Performed the experiments	Investigation	YES
4399882	25881302	OC	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Acquired data	Analyzed the data	Analyzed the data	Formal analysis	YES
4399882	25881302	OC	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Acquired data	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399882	25881302	OC	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Acquired data	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399882	25881302	OC	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Acquired data	Acquired data	Performed the experiments	Investigation	YES
4399882	25881302	RMBH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Acquired data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399882	25881302	RMBH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Acquired data	Performed the experiments	Performed the experiments	Investigation	YES
4399882	25881302	RMBH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Acquired data	Analyzed the data	Analyzed the data	Formal analysis	YES
4399882	25881302	RMBH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Acquired data	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399882	25881302	RMBH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Acquired data	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399882	25881302	RMBH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Acquired data	Acquired data	Performed the experiments	Investigation	YES
5454058	28626464	Both authors	2	have made substantial, direct, and intellectual contribution to the work, and approved it for publication	have made substantial, direct, and intellectual contribution to the work, and approved it for publication	-	-	NO
5070165	27760519	CJS	1	Design of experiment	Design of experiment	Conceived and designed the experiments	Methodology	YES
5070165	27760519	CMA	1	Design of experiment	Design of experiment	Conceived and designed the experiments	Methodology	YES
5070165	27760519	DSF	1	Design of experiment|Analysis tools|Data analysis|Drafting of manuscript	Design of experiment	Conceived and designed the experiments	Methodology	YES
5070165	27760519	DSF	1	Design of experiment|Analysis tools|Data analysis|Drafting of manuscript	Analysis tools	-	-	NO
5070165	27760519	DSF	1	Design of experiment|Analysis tools|Data analysis|Drafting of manuscript	Data analysis	Analyzed the data	Formal analysis	YES
5070165	27760519	DSF	1	Design of experiment|Analysis tools|Data analysis|Drafting of manuscript	Drafting of manuscript	Wrote the paper	Writing - Original Draft	YES
5070165	27760519	ERF	1	Design of experiment|Analysis tools	Design of experiment	Conceived and designed the experiments	Methodology	YES
5070165	27760519	ERF	1	Design of experiment|Analysis tools	Analysis tools	-	-	NO
5070165	27760519	JEK	1	Design of experiment|Analysis tools	Design of experiment	Conceived and designed the experiments	Methodology	YES
5070165	27760519	JEK	1	Design of experiment|Analysis tools	Analysis tools	-	-	NO
5070165	27760519	JMR	1	Design of experiment|Drafting of manuscript	Design of experiment	Conceived and designed the experiments	Methodology	YES
5070165	27760519	JMR	1	Design of experiment|Drafting of manuscript	Drafting of manuscript	Wrote the paper	Writing - Original Draft	YES
5070165	27760519	MEP	1	Design of experiment	Design of experiment	Conceived and designed the experiments	Methodology	YES
5070165	27760519	MFR	1	Design of experiment	Design of experiment	Conceived and designed the experiments	Methodology	YES
5070165	27760519	SJL	1	Design of experiment|Drafting of manuscript	Design of experiment	Conceived and designed the experiments	Methodology	YES
5070165	27760519	SJL	1	Design of experiment|Drafting of manuscript	Drafting of manuscript	Wrote the paper	Writing - Original Draft	YES
2737120	19738913	MK	2	drafted manuscript versions	drafted manuscript versions	Wrote the paper	Writing - Original Draft	YES
4399883	25881086	AT	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399883	25881086	AT	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399883	25881086	CTX	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399883	25881086	CTX	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399883	25881086	PFG	PLoS5	Analyzed the data|Wrote the paper|Carried out the statistical analysis and created the figures	Analyzed the data	Analyzed the data	Formal analysis	YES
4399883	25881086	PFG	PLoS5	Analyzed the data|Wrote the paper|Carried out the statistical analysis and created the figures	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399883	25881086	PFG	PLoS5	Analyzed the data|Wrote the paper|Carried out the statistical analysis and created the figures	Carried out the statistical analysis and created the figures	Analyzed the data	Formal analysis|Visualization	YES
4399883	25881086	TO	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399883	25881086	TO	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399883	25881086	YWH	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399883	25881086	YWH	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3833104	24242262	AB	2	participated in data analysis, data cleaning and the data collection process	participated in data analysis, data cleaning and the data collection process	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
3833104	24242262	AJ	2	led the data analysis of the stigma measures and developed the manuscript	led the data analysis of the stigma measures and developed the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3833104	24242262	KR	2	participated in data analysis, training and report writing	participated in data analysis, training and report writing	Analyzed the data|Wrote the paper	Formal analysis	YES
3833104	24242262	NM	2	participated in data analysis, data cleaning and the data collection process	participated in data analysis, data cleaning and the data collection process	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
3833104	24242262	PO	2	participated in data analysis and supported the implementation of project activities	participated in data analysis and supported the implementation of project activities	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3833104	24242262	RN	2	led and coordinated the data collection process and participated in data analysis	led and coordinated the data collection process and participated in data analysis	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation|Project administration	YES
3833104	24242262	RT	2	participated in data analysis, data cleaning and the data collection process	participated in data analysis, data cleaning and the data collection process	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
4399884	25880993	ALM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399884	25880993	ALM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399884	25880993	ALM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399884	25880993	ALM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399884	25880993	ALM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399884	25880993	FEP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399884	25880993	FEP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399884	25880993	FEP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399884	25880993	FEP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399884	25880993	FEP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399884	25880993	GWA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399884	25880993	GWA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399884	25880993	GWA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399884	25880993	GWA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399884	25880993	GWA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399884	25880993	LB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399884	25880993	LB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399884	25880993	LB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399884	25880993	LB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399884	25880993	LB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399884	25880993	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399884	25880993	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399884	25880993	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399884	25880993	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399884	25880993	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5454074	28626463	AG	2	conceived and wrote the manuscript	conceived and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5454074	28626463	PC	2	conceived and wrote the manuscript	conceived and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5454074	28626463	WW	2	conceived and wrote the manuscript	conceived and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5070194	27756219	DL	2	performed qpcr analysis and participated in the sequence alignment	performed qpcr analysis and participated in the sequence alignment	Performed the experiments	Investigation	YES
5070194	27756219	JP	2	conceived the study|carried out bioinformatics data analysis|wrote the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5070194	27756219	JP	2	conceived the study|carried out bioinformatics data analysis|wrote the manuscript	carried out bioinformatics data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5070194	27756219	JP	2	conceived the study|carried out bioinformatics data analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5070194	27756219	PC	2	critically reviewed the manuscript	critically reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5070194	27756219	WW	2	conceived the study|carried out bioinformatics data analysis|critically reviewed the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5070194	27756219	WW	2	conceived the study|carried out bioinformatics data analysis|critically reviewed the manuscript	carried out bioinformatics data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5070194	27756219	WW	2	conceived the study|carried out bioinformatics data analysis|critically reviewed the manuscript	critically reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5070194	27756219	XY	2	performed qpcr analysis and participated in the sequence alignment	performed qpcr analysis and participated in the sequence alignment	Performed the experiments	Investigation	YES
5070194	27756219	YW	2	conceived the study|wrote the manuscript|critically reviewed the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5070194	27756219	YW	2	conceived the study|wrote the manuscript|critically reviewed the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5070194	27756219	YW	2	conceived the study|wrote the manuscript|critically reviewed the manuscript	critically reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5070194	27756219	ZS	2	performed qpcr analysis and participated in the sequence alignment	performed qpcr analysis and participated in the sequence alignment	Performed the experiments	Investigation	YES
3833105	24242263	BS	2	led the implementation as well as authoring sections of the manuscript	led the implementation as well as authoring sections of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3833105	24242263	CK	2	led the study development and provided a critical review of the manuscript	led the study development and provided a critical review of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3833105	24242263	DA	2	led the implementation as well as authoring sections of the manuscript	led the implementation as well as authoring sections of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3833105	24242263	SDB	2	led the study development and provided a critical review of the manuscript	led the study development and provided a critical review of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3833105	24242263	SK	2	consulted on analyses and provided a review of the manuscript	consulted on analyses and provided a review of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
3833105	24242263	XM	2	led the implementation as well as authoring sections of the manuscript	led the implementation as well as authoring sections of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3833105	24242263	ZM	2	led the study development and provided a critical review of the manuscript	led the study development and provided a critical review of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4426775	26000303	Shui-Juan Zhang	2	contributed equally to this work	contributed equally to this work	-	-	NO
4426775	26000303	Zhi-Cheng Zhang	2	contributed equally to this work	contributed equally to this work	-	-	NO
2771264	19888432	DDK	1	Manuscript preparation	Manuscript preparation	Wrote the paper	Writing - Original Draft	YES
2771264	19888432	DJP	1	Study design|Manuscript preparation	Study design	Conceived and designed the experiments	Methodology	YES
2771264	19888432	DJP	1	Study design|Manuscript preparation	Manuscript preparation	Wrote the paper	Writing - Original Draft	YES
2771264	19888432	RAK	1	Study design|Manuscript preparation	Study design	Conceived and designed the experiments	Methodology	YES
2771264	19888432	RAK	1	Study design|Manuscript preparation	Manuscript preparation	Wrote the paper	Writing - Original Draft	YES
4399885	25881231	AA	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4399885	25881231	AH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399885	25881231	AH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399885	25881231	AH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399885	25881231	AH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399885	25881231	AM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4399885	25881231	AT	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4399885	25881231	AU	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4399885	25881231	AU	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399885	25881231	HF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399885	25881231	HF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399885	25881231	HF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399885	25881231	HF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399885	25881231	KH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399885	25881231	KH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399885	25881231	KN	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4399885	25881231	LM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4399885	25881231	MS	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399885	25881231	MS	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399885	25881231	SS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4399885	25881231	TK	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399885	25881231	TK	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5454077	28626467	ADG	2	designed the experiments, carried the drought stress experiment, generated the physiological data, analyzed and interpreted the microarray data, interpreted the morphological, physiological and molecular results, conducted the in silico analysis of the genomic and protein sequence of hvcbp20, performed the 3d modeling of the hvcbp20 protein and wrote the manuscript	designed the experiments, carried the drought stress experiment, generated the physiological data, analyzed and interpreted the microarray data, interpreted the morphological, physiological and molecular results, conducted the in silico analysis of the genomic and protein sequence of hvcbp20, performed the 3d modeling of the hvcbp20 protein and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5454077	28626467	AP	2	identified the hvcbp20 genomic sequence	identified the hvcbp20 genomic sequence	Performed the experiments	Investigation	YES
5454077	28626467	AS	2	performed the drought experiment and prepared the material for the microarrays	performed the drought experiment and prepared the material for the microarrays	Performed the experiments	Investigation	YES
5454077	28626467	IS	2	designed the study, contributed to the development of the tilling mutants and participated in writing the manuscript	designed the study, contributed to the development of the tilling mutants and participated in writing the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5454077	28626467	KS	2	participated in the photosynthesis analysis	participated in the photosynthesis analysis	-	-	NO
5454077	28626467	MG	2	performed the tilling screen	performed the tilling screen	Performed the experiments	Investigation	YES
5454077	28626467	MK	2	performed the drought experiment and prepared the material for the microarrays	performed the drought experiment and prepared the material for the microarrays	Performed the experiments	Investigation	YES
5454077	28626467	MM	2	performed the sem analyses	performed the sem analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5454077	28626467	MS	2	performed the image analyses	performed the image analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
5454077	28626467	PG	2	performed the tilling screen	performed the tilling screen	Performed the experiments	Investigation	YES
5454077	28626467	TP	2	performed the analysis of the aba level	performed the analysis of the aba level	Performed the experiments	Investigation	YES
5454077	28626467	ZSK	2	identified the hvcbp20 genomic sequence	identified the hvcbp20 genomic sequence	Performed the experiments	Investigation	YES
5070307	27756224	DH	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5070307	27756224	LG	PLoS52	generated samples for rna seq|wrote the paper	generated samples for rna seq	Performed the experiments	Investigation	YES
5070307	27756224	LG	PLoS52	generated samples for rna seq|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5070307	27756224	SH	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3833106	24242268	ALS	2	conceptualized the study, led the systematic review process and drafted the first version of this article	conceptualized the study, led the systematic review process and drafted the first version of this article	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
3833106	24242268	CEH	2	contributed to the title, abstract, and full-text reviews and the data abstraction|also authored sections of this article|conducted the quality assessment	contributed to the title, abstract, and full-text reviews and the data abstraction	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Original Draft|Writing - Review & Editing	YES
3833106	24242268	CEH	2	contributed to the title, abstract, and full-text reviews and the data abstraction|also authored sections of this article|conducted the quality assessment	also authored sections of this article	Wrote the paper	Writing - Original Draft	YES
3833106	24242268	CEH	2	contributed to the title, abstract, and full-text reviews and the data abstraction|also authored sections of this article|conducted the quality assessment	conducted the quality assessment	Performed the experiments	Investigation|Validation	YES
3833106	24242268	JKL	2	developed and implemented the search strategy, led the title, abstract, full-text review and data abstraction processes, and authored sections of this article|conducted the quality assessment	developed and implemented the search strategy, led the title, abstract, full-text review and data abstraction processes, and authored sections of this article	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
3833106	24242268	JKL	2	developed and implemented the search strategy, led the title, abstract, full-text review and data abstraction processes, and authored sections of this article|conducted the quality assessment	conducted the quality assessment	Performed the experiments	Investigation|Validation	YES
3833106	24242268	LMB	2	contributed to the title, abstract, and full-text reviews and the data abstraction|also authored sections of this article	contributed to the title, abstract, and full-text reviews and the data abstraction	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Original Draft|Writing - Review & Editing	YES
3833106	24242268	LMB	2	contributed to the title, abstract, and full-text reviews and the data abstraction|also authored sections of this article	also authored sections of this article	Wrote the paper	Writing - Original Draft	YES
3833106	24242268	SB	2	contributed to the development of the search protocol, provided guidance on the quality assessment and provided critical review of this article	contributed to the development of the search protocol, provided guidance on the quality assessment and provided critical review of this article	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Validation|Writing - Original Draft|Writing - Review & Editing	YES
4399887	25879867	AK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399887	25879867	AK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399887	25879867	AK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399887	25879867	EZ	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399887	25879867	EZ	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399887	25879867	FS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399887	25879867	FS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399887	25879867	FS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399887	25879867	FS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399887	25879867	GV	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399887	25879867	GV	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399887	25879867	JV	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399887	25879867	JV	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399887	25879867	JV	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399887	25879867	NA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399887	25879867	NA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399887	25879867	NA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399887	25879867	NU	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399887	25879867	NU	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399887	25879867	NU	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399887	25879867	PC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399887	25879867	PC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399887	25879867	PC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399887	25879867	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399887	25879867	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399887	25879867	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399887	25879867	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399887	25879867	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4426782	26000300	Guang Yang	2	contributed equally to this work	contributed equally to this work	-	-	NO
4426782	26000300	Minjie Gao	2	contributed equally to this work	contributed equally to this work	-	-	NO
5070370	27756223	All the authors	2	wrote, reviewed and approved the final manuscript	wrote, reviewed and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5070370	27756223	SG	2	assisted in the implementation of methods	assisted in the implementation of methods	Performed the experiments	Investigation	YES
5070370	27756223	SJ	2	under the supervision of ag carried out the analysis and reviewed the results	under the supervision of ag carried out the analysis and reviewed the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Supervision	YES
5454542	28626466	All authors	2	contributed to manuscript preparation|have read and approved the final manuscript	contributed to manuscript preparation	Wrote the paper	Writing - Original Draft	YES
5454542	28626466	All authors	2	contributed to manuscript preparation|have read and approved the final manuscript	have read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
3833107	24242258	ACT	2	conceived the study|acquired the data|analyzed the data and prepared the initial draft of the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
3833107	24242258	ACT	2	conceived the study|acquired the data|analyzed the data and prepared the initial draft of the manuscript	acquired the data	Performed the experiments	Investigation	YES
3833107	24242258	ACT	2	conceived the study|acquired the data|analyzed the data and prepared the initial draft of the manuscript	analyzed the data and prepared the initial draft of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3833107	24242258	AER	2	acquired the data	acquired the data	Performed the experiments	Investigation	YES
3833107	24242258	AGO	2	acquired the data	acquired the data	Performed the experiments	Investigation	YES
3833107	24242258	All authors	2	assisted in interpretation of the data, revised the manuscript for important intellectual content, and approved the final version of the manuscript	assisted in interpretation of the data, revised the manuscript for important intellectual content, and approved the final version of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
3833107	24242258	ITK	2	analyzed the data and prepared the initial draft of the manuscript	analyzed the data and prepared the initial draft of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4399890	25879934	AN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399890	25879934	AN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399890	25879934	AN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399890	25879934	AN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399890	25879934	AN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399890	25879934	MW	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4399890	25879934	MW	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4399890	25879934	SDM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399890	25879934	SDM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399890	25879934	SDM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399890	25879934	SDM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4426894	26000290	All the authors	2	have read and approved the content of the final paper	have read and approved the content of the final paper	-	-	NO
4426894	26000290	Chih-Hao Lu	2	developed and implemented the methods|carried out the analysis|drafted the paper|supervised the work|contributed equally to this work	developed and implemented the methods	Performed the experiments	Investigation|Methodology	YES
4426894	26000290	Chih-Hao Lu	2	developed and implemented the methods|carried out the analysis|drafted the paper|supervised the work|contributed equally to this work	carried out the analysis	Performed the experiments	Investigation	YES
4426894	26000290	Chih-Hao Lu	2	developed and implemented the methods|carried out the analysis|drafted the paper|supervised the work|contributed equally to this work	drafted the paper	Wrote the paper	Writing - Original Draft	YES
4426894	26000290	Chih-Hao Lu	2	developed and implemented the methods|carried out the analysis|drafted the paper|supervised the work|contributed equally to this work	supervised the work	-	Supervision	YES
4426894	26000290	Chih-Hao Lu	2	developed and implemented the methods|carried out the analysis|drafted the paper|supervised the work|contributed equally to this work	contributed equally to this work	-	-	NO
4426894	26000290	Chin-Sheng Yu	2	developed and implemented the methods|carried out the analysis|contributed equally to this work	developed and implemented the methods	Performed the experiments	Investigation|Methodology	YES
4426894	26000290	Chin-Sheng Yu	2	developed and implemented the methods|carried out the analysis|contributed equally to this work	carried out the analysis	Performed the experiments	Investigation	YES
4426894	26000290	Chin-Sheng Yu	2	developed and implemented the methods|carried out the analysis|contributed equally to this work	contributed equally to this work	-	-	NO
4426894	26000290	Jin-Yi Chen	2	carried out the analysis	carried out the analysis	Performed the experiments	Investigation	YES
4426894	26000290	Yu-Feng Lin	2	carried out the analysis|drafted the paper	carried out the analysis	Performed the experiments	Investigation	YES
4426894	26000290	Yu-Feng Lin	2	carried out the analysis|drafted the paper	drafted the paper	Wrote the paper	Writing - Original Draft	YES
5072325	27765019	AM	2	provided samples, performed sample preparation, degradation and sequencing experiments|performed bioinformatics analysis and created scripts used in the paper	provided samples, performed sample preparation, degradation and sequencing experiments	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5072325	27765019	AM	2	provided samples, performed sample preparation, degradation and sequencing experiments|performed bioinformatics analysis and created scripts used in the paper	performed bioinformatics analysis and created scripts used in the paper	Performed the experiments	Formal analysis|Investigation	YES
5072325	27765019	BC	2	provided samples, performed sample preparation, degradation and sequencing experiments	provided samples, performed sample preparation, degradation and sequencing experiments	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5072325	27765019	BK	2	conceived the study|oversaw the project and wrote the paper	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5072325	27765019	BK	2	conceived the study|oversaw the project and wrote the paper	oversaw the project and wrote the paper	Wrote the paper	Supervision|Writing - Original Draft	YES
5072325	27765019	EK	2	conceived the study|oversaw the project and wrote the paper	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5072325	27765019	EK	2	conceived the study|oversaw the project and wrote the paper	oversaw the project and wrote the paper	Wrote the paper	Supervision|Writing - Original Draft	YES
5072325	27765019	JB	2	provided samples, performed sample preparation, degradation and sequencing experiments	provided samples, performed sample preparation, degradation and sequencing experiments	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5072325	27765019	JD	2	performed bioinformatics analysis and created scripts used in the paper|conceived the study|oversaw the project and wrote the paper	performed bioinformatics analysis and created scripts used in the paper	Performed the experiments	Formal analysis|Investigation	YES
5072325	27765019	JD	2	performed bioinformatics analysis and created scripts used in the paper|conceived the study|oversaw the project and wrote the paper	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5072325	27765019	JD	2	performed bioinformatics analysis and created scripts used in the paper|conceived the study|oversaw the project and wrote the paper	oversaw the project and wrote the paper	Wrote the paper	Supervision|Writing - Original Draft	YES
5072325	27765019	JJ	2	provided samples, performed sample preparation, degradation and sequencing experiments	provided samples, performed sample preparation, degradation and sequencing experiments	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5072325	27765019	KH	2	conceived the study|oversaw the project and wrote the paper	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5072325	27765019	KH	2	conceived the study|oversaw the project and wrote the paper	oversaw the project and wrote the paper	Wrote the paper	Supervision|Writing - Original Draft	YES
5072325	27765019	KR	2	provided samples, performed sample preparation, degradation and sequencing experiments	provided samples, performed sample preparation, degradation and sequencing experiments	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5072325	27765019	NF	2	performed bioinformatics analysis and created scripts used in the paper	performed bioinformatics analysis and created scripts used in the paper	Performed the experiments	Formal analysis|Investigation	YES
5072325	27765019	RJ	2	oversaw the project and wrote the paper	oversaw the project and wrote the paper	Wrote the paper	Supervision|Writing - Original Draft	YES
5072325	27765019	UA	2	provided samples, performed sample preparation, degradation and sequencing experiments	provided samples, performed sample preparation, degradation and sequencing experiments	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5072325	27765019	XW	2	provided samples, performed sample preparation, degradation and sequencing experiments|provided samples, performed sample preparation, degradation and sequencing experiments	provided samples, performed sample preparation, degradation and sequencing experiments	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5072325	27765019	XW	2	provided samples, performed sample preparation, degradation and sequencing experiments|provided samples, performed sample preparation, degradation and sequencing experiments	provided samples, performed sample preparation, degradation and sequencing experiments	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5459896	28634485	GH	PLoS52	conducted the experiments and collected the data|analyzed the data|wrote the paper	conducted the experiments and collected the data	Performed the experiments	Investigation	YES
5459896	28634485	GH	PLoS52	conducted the experiments and collected the data|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5459896	28634485	GH	PLoS52	conducted the experiments and collected the data|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5459896	28634485	QZ	PLoS52	conducted the experiments and collected the data	conducted the experiments and collected the data	Performed the experiments	Investigation	YES
5459896	28634485	SP	PLoS52	commented and revised the paper	commented and revised the paper	Wrote the paper	Writing - Review & Editing	YES
5459896	28634485	XW	PLoS52	conducted the experiments and collected the data	conducted the experiments and collected the data	Performed the experiments	Investigation	YES
5459896	28634485	YL	PLoS52	conceived and designed the research|analyzed the data|wrote the paper	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5459896	28634485	YL	PLoS52	conceived and designed the research|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5459896	28634485	YL	PLoS52	conceived and designed the research|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5828705	29503508	All authors	2	have given approval to the final version of the manuscript	have given approval to the final version of the manuscript	-	-	NO
3833108	24242267	AG	2	have all read and approved the final manuscript	have all read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
3833108	24242267	JC	2	have all read and approved the final manuscript	have all read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
3833108	24242267	KH	2	have all read and approved the final manuscript	have all read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
3833108	24242267	PM	2	have all read and approved the final manuscript	have all read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
3833108	24242267	SG	2	took the lead in all aspects of the article writing	took the lead in all aspects of the article writing	Wrote the paper	-	YES
3833108	24242267	TE	2	have all read and approved the final manuscript	have all read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4399906	25880329	CFK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Revised manuscript critically for important intellectual content	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399906	25880329	CFK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Revised manuscript critically for important intellectual content	Performed the experiments	Performed the experiments	Investigation	YES
4399906	25880329	CFK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Revised manuscript critically for important intellectual content	Analyzed the data	Analyzed the data	Formal analysis	YES
4399906	25880329	CFK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Revised manuscript critically for important intellectual content	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399906	25880329	CFK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Revised manuscript critically for important intellectual content	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399906	25880329	CFK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Revised manuscript critically for important intellectual content	Revised manuscript critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4399906	25880329	HH	PLoS5	Conceived and designed the experiments|Performed the experiments|Revised manuscript critically for important intellectual content	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399906	25880329	HH	PLoS5	Conceived and designed the experiments|Performed the experiments|Revised manuscript critically for important intellectual content	Performed the experiments	Performed the experiments	Investigation	YES
4399906	25880329	HH	PLoS5	Conceived and designed the experiments|Performed the experiments|Revised manuscript critically for important intellectual content	Revised manuscript critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4399906	25880329	JRL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Revised manuscript critically for important intellectual content	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399906	25880329	JRL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Revised manuscript critically for important intellectual content	Performed the experiments	Performed the experiments	Investigation	YES
4399906	25880329	JRL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Revised manuscript critically for important intellectual content	Analyzed the data	Analyzed the data	Formal analysis	YES
4399906	25880329	JRL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Revised manuscript critically for important intellectual content	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399906	25880329	JRL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Revised manuscript critically for important intellectual content	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399906	25880329	JRL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Revised manuscript critically for important intellectual content	Revised manuscript critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4399906	25880329	PHK	PLoS5	Conceived and designed the experiments|Performed the experiments|Revised manuscript critically for important intellectual content	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399906	25880329	PHK	PLoS5	Conceived and designed the experiments|Performed the experiments|Revised manuscript critically for important intellectual content	Performed the experiments	Performed the experiments	Investigation	YES
4399906	25880329	PHK	PLoS5	Conceived and designed the experiments|Performed the experiments|Revised manuscript critically for important intellectual content	Revised manuscript critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5459913	28634483	AS	2	conceptualized, initiated and designed the research work, and wrote the manuscript	conceptualized, initiated and designed the research work, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Writing - Original Draft	YES
5459913	28634483	AT	2	helped in critical assessment and execution of experimental plan	helped in critical assessment and execution of experimental plan	Performed the experiments	Investigation	YES
5459913	28634483	MA	2	carried out the biochemical and molecular studies, data collection and their analysis	carried out the biochemical and molecular studies, data collection and their analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5459913	28634483	MKS	2	carried out the biochemical and molecular studies, data collection and their analysis	carried out the biochemical and molecular studies, data collection and their analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5459913	28634483	MS	2	carried out the biochemical and molecular studies, data collection and their analysis	carried out the biochemical and molecular studies, data collection and their analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5459913	28634483	OY	2	helped in maintaining experimental materials, conducting the experiments under controlled conditions, sample collection, etc	helped in maintaining experimental materials, conducting the experiments under controlled conditions, sample collection, etc	Performed the experiments	Investigation	YES
5459913	28634483	SAM	2	helped in critical assessment and execution of experimental plan	helped in critical assessment and execution of experimental plan	Performed the experiments	Investigation	YES
5459913	28634483	SK	2	conceptualized, initiated and designed the research work, and wrote the manuscript	conceptualized, initiated and designed the research work, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Writing - Original Draft	YES
5073745	27769163	AE	PLoS52	conceived the study and designed experiments	conceived the study and designed experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5073745	27769163	ASD	PLoS52	performed the experiments|performed microarray experiments|carried out analysis and interpretation of experimental data including bioinformatics analyses|read and revised by all other authors	performed the experiments	Performed the experiments	Investigation	YES
5073745	27769163	ASD	PLoS52	performed the experiments|performed microarray experiments|carried out analysis and interpretation of experimental data including bioinformatics analyses|read and revised by all other authors	performed microarray experiments	Performed the experiments	Investigation	YES
5073745	27769163	ASD	PLoS52	performed the experiments|performed microarray experiments|carried out analysis and interpretation of experimental data including bioinformatics analyses|read and revised by all other authors	carried out analysis and interpretation of experimental data including bioinformatics analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5073745	27769163	ASD	PLoS52	performed the experiments|performed microarray experiments|carried out analysis and interpretation of experimental data including bioinformatics analyses|read and revised by all other authors	read and revised by all other authors	Wrote the paper	Writing - Review & Editing	YES
5073745	27769163	DB	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5073745	27769163	DM	PLoS52	performed the experiments|read and revised by all other authors	performed the experiments	Performed the experiments	Investigation	YES
5073745	27769163	DM	PLoS52	performed the experiments|read and revised by all other authors	read and revised by all other authors	Wrote the paper	Writing - Review & Editing	YES
5073745	27769163	EB	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5073745	27769163	GR	PLoS52	carried out anova analysis on microarray data	carried out anova analysis on microarray data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5073745	27769163	LT	PLoS52	performed microarray experiments	performed microarray experiments	Performed the experiments	Investigation	YES
5073745	27769163	MS	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5073745	27769163	OC	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5073745	27769163	RB	PLoS52	conceived the study and designed experiments|carried out analysis and interpretation of experimental data including bioinformatics analyses|read and revised by all other authors	conceived the study and designed experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5073745	27769163	RB	PLoS52	conceived the study and designed experiments|carried out analysis and interpretation of experimental data including bioinformatics analyses|read and revised by all other authors	carried out analysis and interpretation of experimental data including bioinformatics analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5073745	27769163	RB	PLoS52	conceived the study and designed experiments|carried out analysis and interpretation of experimental data including bioinformatics analyses|read and revised by all other authors	read and revised by all other authors	Wrote the paper	Writing - Review & Editing	YES
3833117	24242261	All authors	2	contributed to the preparation of the manuscript and approved the final draft	contributed to the preparation of the manuscript and approved the final draft	Wrote the paper	Writing - Original Draft	YES
3833117	24242261	C. Lin	2	conducted statistical analysis and participated in writing the paper	conducted statistical analysis and participated in writing the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3833117	24242261	J. Guan	2	was responsible for study implementation in the field	was responsible for study implementation in the field	Performed the experiments	Investigation	YES
3833117	24242261	L. Li	2	oversaw the design and implementation of the trial and the writing of the article	oversaw the design and implementation of the trial and the writing of the article	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Supervision|Writing - Original Draft	YES
3833117	24242261	Z. Wu	2	oversaw the design and implementation of the trial and the writing of the article	oversaw the design and implementation of the trial and the writing of the article	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Supervision|Writing - Original Draft	YES
4399908	25879665	JZ	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4399908	25879665	JZ	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4399908	25879665	LC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399908	25879665	LC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399908	25879665	LC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399908	25879665	LC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399908	25879665	SC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4399908	25879665	WH	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4399908	25879665	WH	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399908	25879665	XS	PLoS5	Conceived and designed the experiments|Wrote the paper|Provided instruments used in the experiment	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399908	25879665	XS	PLoS5	Conceived and designed the experiments|Wrote the paper|Provided instruments used in the experiment	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399908	25879665	XS	PLoS5	Conceived and designed the experiments|Wrote the paper|Provided instruments used in the experiment	Provided instruments used in the experiment	Contributed reagents/materials/analysis tools	Resources	YES
4399908	25879665	YL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4399908	25879665	YL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399908	25879665	YZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4916501	26248609	All authors	2	contributed to the study conception and design	contributed to the study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4916501	26248609	RB	2	performed the data extraction and raw data analysis for the case only design studies|wrote the first draft and all authors contributed with critical comments to the final version	performed the data extraction and raw data analysis for the case only design studies	Conceived and designed the experiments|Analyzed the data	Data curation|Formal analysis|Methodology	YES
4916501	26248609	RB	2	performed the data extraction and raw data analysis for the case only design studies|wrote the first draft and all authors contributed with critical comments to the final version	wrote the first draft and all authors contributed with critical comments to the final version	Wrote the paper	Writing - Original Draft	YES
5459925	28634481	D-HM	2	provided reagents	provided reagents	Contributed reagents/materials/analysis tools	Resources	YES
5459925	28634481	MC	2	provided reagents	provided reagents	Contributed reagents/materials/analysis tools	Resources	YES
5459925	28634481	S-CC	2	contributed with valuable discussions	contributed with valuable discussions	-	-	NO
5459925	28634481	S-PZ	2	conducted the bioinformatic work, generated and analyzed data, and wrote the manuscript	conducted the bioinformatic work, generated and analyzed data, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5459925	28634481	T-FY	2	performed experiments and analyzed data	performed experiments and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5459925	28634481	W-JZ	2	performed experiments and analyzed data	performed experiments and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5459925	28634481	WZ	2	performed experiments and analyzed data	performed experiments and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5459925	28634481	X-HZ	2	contributed with valuable discussions	contributed with valuable discussions	-	-	NO
5459925	28634481	Y-BZ	2	performed experiments and analyzed data	performed experiments and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5459925	28634481	Y-XW	2	provided reagents	provided reagents	Contributed reagents/materials/analysis tools	Resources	YES
5459925	28634481	Z-SX	2	coordinated the project, conceived and designed experiments, and edited the manuscript	coordinated the project, conceived and designed experiments, and edited the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Review & Editing	YES
5073746	27765014	AP	2	performed physiological experiments and measurements, analyzed and interpreted the data|conceived the study and helped drafting the manuscript	performed physiological experiments and measurements, analyzed and interpreted the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5073746	27765014	AP	2	performed physiological experiments and measurements, analyzed and interpreted the data|conceived the study and helped drafting the manuscript	conceived the study and helped drafting the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5073746	27765014	CO	2	measured xanthophyll and chlorophyll levels, and analyzed the data	measured xanthophyll and chlorophyll levels, and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5073746	27765014	FM	2	measured xanthophyll and chlorophyll levels, and analyzed the data	measured xanthophyll and chlorophyll levels, and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5073746	27765014	GBT	2	helped to design the experimental plan and interpret the transcriptomic data	helped to design the experimental plan and interpret the transcriptomic data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5073746	27765014	MF	2	helped with the microarray hybridizations and data analysis	helped with the microarray hybridizations and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5073746	27765014	MG	2	performed physiological experiments and measurements, analyzed and interpreted the data	performed physiological experiments and measurements, analyzed and interpreted the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5073746	27765014	MP	2	provided supervision and coordination	provided supervision and coordination	-	Project administration|Supervision	YES
5073746	27765014	OS	2	performed physiological experiments and measurements, analyzed and interpreted the data	performed physiological experiments and measurements, analyzed and interpreted the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5073746	27765014	PP	2	performed the correlation network and switch genes analysis	performed the correlation network and switch genes analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5073746	27765014	SDS	2	performed microarray hybridizations, analyzed and interpreted transcriptomic data and wrote the manuscript	performed microarray hybridizations, analyzed and interpreted transcriptomic data and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5073746	27765014	SP	2	conceived the study and helped drafting the manuscript	conceived the study and helped drafting the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5073746	27765014	ST	2	performed physiological experiments and measurements, analyzed and interpreted the data	performed physiological experiments and measurements, analyzed and interpreted the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5073746	27765014	SZ	2	helped to design the experimental plan and interpret the transcriptomic data	helped to design the experimental plan and interpret the transcriptomic data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5073746	27765014	TF	2	performed physiological experiments and measurements, analyzed and interpreted the data	performed physiological experiments and measurements, analyzed and interpreted the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3833188	24242256	CS	2	critically reviewed drafts and contributed to the content	critically reviewed drafts and contributed to the content	Wrote the paper	Writing - Original Draft	YES
3833188	24242256	DB	2	coordinated data collection	coordinated data collection	Performed the experiments	Investigation|Project administration	YES
3833188	24242256	GM	2	participated in coding and/or interpreting data	participated in coding and/or interpreting data	Analyzed the data	Formal analysis	YES
3833188	24242256	GWM	2	participated in coding and/or interpreting data	participated in coding and/or interpreting data	Analyzed the data	Formal analysis	YES
3833188	24242256	IH	2	participated in coding and/or interpreting data	participated in coding and/or interpreting data	Analyzed the data	Formal analysis	YES
3833188	24242256	JS	2	critically reviewed drafts and contributed to the content	critically reviewed drafts and contributed to the content	Wrote the paper	Writing - Original Draft	YES
3833188	24242256	MR	2	participated in coding and/or interpreting data	participated in coding and/or interpreting data	Analyzed the data	Formal analysis	YES
3833188	24242256	MS	2	critically reviewed drafts and contributed to the content	critically reviewed drafts and contributed to the content	Wrote the paper	Writing - Original Draft	YES
4399910	25879682	ADA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399910	25879682	ADA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399910	25879682	ADA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399910	25879682	ADA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399910	25879682	AET	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399910	25879682	CC	PLoS5	Contributed to the study design and revised the manuscript	Contributed to the study design and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
4399910	25879682	EA	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399910	25879682	EA	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399910	25879682	EP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4399910	25879682	FG	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399910	25879682	FL	PLoS5	Contributed to the study design and revised the manuscript	Contributed to the study design and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
4399910	25879682	LR	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4399910	25879682	PM	PLoS5	Contributed to the study design and revised the manuscript	Contributed to the study design and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
4399910	25879682	RB	PLoS5	Contributed to the study design and revised the manuscript	Contributed to the study design and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5460295	28634482	CP	2	performed the rna extraction, contributed to the enzymatic and hplc analyses and wrote the manuscript	performed the rna extraction, contributed to the enzymatic and hplc analyses and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5460295	28634482	GA	2	sampled the material and contributed to the enzymatic and hplc analysis	sampled the material and contributed to the enzymatic and hplc analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5460295	28634482	GT	2	designed the microarray experiments and critically revised the manuscript	designed the microarray experiments and critically revised the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
5460295	28634482	GV	2	sampled the material and contributed to the enzymatic and hplc analysis	sampled the material and contributed to the enzymatic and hplc analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5460295	28634482	IF	2	conceived and supervised the study, wrote and critically revised the manuscript	conceived and supervised the study, wrote and critically revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
5460295	28634482	NM	2	sampled the material and contributed to the enzymatic and hplc analysis	sampled the material and contributed to the enzymatic and hplc analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5460295	28634482	SDS	2	conducted the microarray experiments, interpreted the microarray data and wrote the manuscript	conducted the microarray experiments, interpreted the microarray data and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5460295	28634482	SZ	2	designed the microarray experiments and critically revised the manuscript	designed the microarray experiments and critically revised the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
4399911	25881188	EB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399911	25881188	EB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4399911	25881188	EB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4399911	25881188	JC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399911	25881188	JC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399911	25881188	JC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399911	25881188	KJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399911	25881188	KJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399911	25881188	KJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399911	25881188	KJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4949640	26112821	All authors	2	contributed to the study conception and design	contributed to the study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4949640	26112821	DB	2	performed data extraction and raw data analysis	performed data extraction and raw data analysis	Analyzed the data	Data curation|Formal analysis	YES
4949640	26112821	GR	2	wrote the first draft, and all authors contributed with critical comments to the final version	wrote the first draft, and all authors contributed with critical comments to the final version	Wrote the paper	Writing - Original Draft	YES
4949640	26112821	IJD	2	wrote the first draft, and all authors contributed with critical comments to the final version	wrote the first draft, and all authors contributed with critical comments to the final version	Wrote the paper	Writing - Original Draft	YES
4949640	26112821	JL	2	wrote the first draft, and all authors contributed with critical comments to the final version	wrote the first draft, and all authors contributed with critical comments to the final version	Wrote the paper	Writing - Original Draft	YES
3833189	24242266	AJ	2	holds the primary responsibility for cross-site data analysis and drafting of manuscript	holds the primary responsibility for cross-site data analysis and drafting of manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3833189	24242266	LN	2	holds the primary responsibility for conceptualization and coordination of the multi-site process and drafting of the manuscript	holds the primary responsibility for conceptualization and coordination of the multi-site process and drafting of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Project administration|Writing - Original Draft	YES
3833189	24242266	Puerto Rico	2	individual site and cross-site analysis and manuscript review|individual site analysis and manuscript review	individual site and cross-site analysis and manuscript review	Wrote the paper	Writing - Review & Editing	YES
3833189	24242266	Puerto Rico	2	individual site and cross-site analysis and manuscript review|individual site analysis and manuscript review	individual site analysis and manuscript review	Wrote the paper	Writing - Review & Editing	YES
4426909	26000283	Chen-Xia Xu	2	contribute equally	contribute equally	-	-	NO
4426909	26000283	Miao-Lian Zhang	2	contribute equally	contribute equally	-	-	NO
5460589	28634484	CZ	PLoS52	designed and wrote the paper	designed and wrote the paper	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
5460589	28634484	LJ	PLoS52	designed and wrote the paper	designed and wrote the paper	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
5460589	28634484	TL	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5460589	28634484	WW	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399912	25879218	HK	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399912	25879218	HK	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399912	25879218	JAS	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399912	25879218	JAS	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399912	25879218	KS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399912	25879218	KS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399912	25879218	KS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399912	25879218	KS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399912	25879218	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399912	25879218	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399912	25879218	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399912	25879218	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399912	25879218	ON	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399912	25879218	ON	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399912	25879218	ON	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399912	25879218	RS	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399912	25879218	RS	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399912	25879218	SO	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399912	25879218	SO	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399912	25879218	SO	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5073747	27769166	BN	2	had a contribution in the general concept of the research scheme and participated in manuscript drafting	had a contribution in the general concept of the research scheme and participated in manuscript drafting	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5073747	27769166	BW	2	had a contribution in the general concept of the research scheme and participated in manuscript drafting	had a contribution in the general concept of the research scheme and participated in manuscript drafting	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5073747	27769166	KW	2	performed bac-fish analysis and prepared fig	performed bac-fish analysis and prepared fig	Performed the experiments	Investigation|Visualization	YES
5073747	27769166	MK	2	carried out sequence annotation, synteny analysis, phylogenetic inference, drafted a manuscript and prepared all figures but one|had a contribution in the general concept of the research scheme and participated in manuscript drafting	carried out sequence annotation, synteny analysis, phylogenetic inference, drafted a manuscript and prepared all figures but one	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Formal analysis|Investigation|Visualization|Writing - Original Draft	YES
5073747	27769166	MK	2	carried out sequence annotation, synteny analysis, phylogenetic inference, drafted a manuscript and prepared all figures but one|had a contribution in the general concept of the research scheme and participated in manuscript drafting	had a contribution in the general concept of the research scheme and participated in manuscript drafting	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5073747	27769166	MN	2	had a contribution in the general concept of the research scheme and participated in manuscript drafting	had a contribution in the general concept of the research scheme and participated in manuscript drafting	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5073747	27769166	SR	2	participated in identification of pebp sequence homologs in analyzed species and assignment of scaffolds to linkage groups	participated in identification of pebp sequence homologs in analyzed species and assignment of scaffolds to linkage groups	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4399913	25881057	SG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399913	25881057	SG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399913	25881057	SG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399913	25881057	SW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399913	25881057	SW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399913	25881057	SW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399913	25881057	SW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5073808	27766957	AGC	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5073808	27766957	FA	2	edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5073808	27766957	FTA	2	performed the array cgh experiments	performed the array cgh experiments	Performed the experiments	Investigation	YES
5073808	27766957	GK	2	edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5073808	27766957	MA	2	edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5073808	27766957	MHQ	2	edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5073808	27766957	MIN	2	designed the study|performed the array cgh experiments|analyzed the data and wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5073808	27766957	MIN	2	designed the study|performed the array cgh experiments|analyzed the data and wrote the manuscript	performed the array cgh experiments	Performed the experiments	Investigation	YES
5073808	27766957	MIN	2	designed the study|performed the array cgh experiments|analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5073808	27766957	MMJ	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5073808	27766957	MR	2	designed the study|analyzed the data and wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5073808	27766957	MR	2	designed the study|analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5073808	27766957	SAA	2	analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5073808	27766957	SKZ	2	analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3833190	24242257	CF	2	gave substantive feedback on the manuscript direction and data interpretation, and were involved in the original conception and operational setup of the main study	gave substantive feedback on the manuscript direction and data interpretation, and were involved in the original conception and operational setup of the main study	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation|Supervision	YES
3833190	24242257	CL	2	gave substantive feedback on the manuscript direction and data interpretation, and were involved in the original conception and operational setup of the main study	gave substantive feedback on the manuscript direction and data interpretation, and were involved in the original conception and operational setup of the main study	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation|Supervision	YES
3833190	24242257	CZ	2	gave substantive feedback on the manuscript direction and data interpretation, and were involved in the original conception and operational setup of the main study	gave substantive feedback on the manuscript direction and data interpretation, and were involved in the original conception and operational setup of the main study	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation|Supervision	YES
3833190	24242257	HVT	2	coordinated the collection and cleaning of data	coordinated the collection and cleaning of data	Performed the experiments	Investigation|Project administration	YES
3833190	24242257	NLM	2	provided local contextual information and advice in the design and implementation of the main study	provided local contextual information and advice in the design and implementation of the main study	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
3833190	24242257	TL	2	devised the analysis, analyzed the data and wrote the manuscript	devised the analysis, analyzed the data and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
3833190	24242257	VFG	2	gave substantive feedback on the manuscript direction and data interpretation, and were involved in the original conception and operational setup of the main study	gave substantive feedback on the manuscript direction and data interpretation, and were involved in the original conception and operational setup of the main study	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation|Supervision	YES
3833190	24242257	VMQ	2	provided local contextual information and advice in the design and implementation of the main study	provided local contextual information and advice in the design and implementation of the main study	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5461256	28638395	AG	2	wrote the manuscript and prepared figures	wrote the manuscript and prepared figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5461256	28638395	AG-C	2	supervised the project and provided funding|revised the final version	supervised the project and provided funding	-	Funding acquisition|Supervision	YES
5461256	28638395	AG-C	2	supervised the project and provided funding|revised the final version	revised the final version	Wrote the paper	Writing - Review & Editing	YES
5461256	28638395	DB	2	performed the research|wrote the manuscript and prepared figures|revised the final version	performed the research	Performed the experiments	Investigation	YES
5461256	28638395	DB	2	performed the research|wrote the manuscript and prepared figures|revised the final version	wrote the manuscript and prepared figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5461256	28638395	DB	2	performed the research|wrote the manuscript and prepared figures|revised the final version	revised the final version	Wrote the paper	Writing - Review & Editing	YES
5461256	28638395	SZ	2	performed the research|wrote the manuscript and prepared figures|revised the final version	performed the research	Performed the experiments	Investigation	YES
5461256	28638395	SZ	2	performed the research|wrote the manuscript and prepared figures|revised the final version	wrote the manuscript and prepared figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5461256	28638395	SZ	2	performed the research|wrote the manuscript and prepared figures|revised the final version	revised the final version	Wrote the paper	Writing - Review & Editing	YES
5461256	28638395	VA	2	supervised the project and provided funding|revised the final version	supervised the project and provided funding	-	Funding acquisition|Supervision	YES
5461256	28638395	VA	2	supervised the project and provided funding|revised the final version	revised the final version	Wrote the paper	Writing - Review & Editing	YES
4399914	25879844	AMG	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Critical revision of the paper for important intellectual content|Administrative, technical, material support, and study supervision	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399914	25879844	AMG	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Critical revision of the paper for important intellectual content|Administrative, technical, material support, and study supervision	Performed the experiments	Performed the experiments	Investigation	YES
4399914	25879844	AMG	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Critical revision of the paper for important intellectual content|Administrative, technical, material support, and study supervision	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399914	25879844	AMG	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Critical revision of the paper for important intellectual content|Administrative, technical, material support, and study supervision	Critical revision of the paper for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4399914	25879844	AMG	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Critical revision of the paper for important intellectual content|Administrative, technical, material support, and study supervision	Administrative, technical, material support, and study supervision	Performed the experiments	Investigation|Project administration|Supervision	YES
4399914	25879844	HRY	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Critical revision of the paper for important intellectual content	Performed the experiments	Performed the experiments	Investigation	YES
4399914	25879844	HRY	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Critical revision of the paper for important intellectual content	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399914	25879844	HRY	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Critical revision of the paper for important intellectual content	Critical revision of the paper for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4399914	25879844	JT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Critical revision of the paper for important intellectual content	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399914	25879844	JT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Critical revision of the paper for important intellectual content	Performed the experiments	Performed the experiments	Investigation	YES
4399914	25879844	JT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Critical revision of the paper for important intellectual content	Analyzed the data	Analyzed the data	Formal analysis	YES
4399914	25879844	JT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Critical revision of the paper for important intellectual content	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399914	25879844	JT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Critical revision of the paper for important intellectual content	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399914	25879844	JT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Critical revision of the paper for important intellectual content	Critical revision of the paper for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4399914	25879844	LCR	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Critical revision of the paper for important intellectual content|Administrative, technical, material support, and study supervision	Performed the experiments	Performed the experiments	Investigation	YES
4399914	25879844	LCR	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Critical revision of the paper for important intellectual content|Administrative, technical, material support, and study supervision	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399914	25879844	LCR	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Critical revision of the paper for important intellectual content|Administrative, technical, material support, and study supervision	Critical revision of the paper for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4399914	25879844	LCR	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Critical revision of the paper for important intellectual content|Administrative, technical, material support, and study supervision	Administrative, technical, material support, and study supervision	Performed the experiments	Investigation|Project administration|Supervision	YES
4399914	25879844	MGB	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Critical revision of the paper for important intellectual content	Performed the experiments	Performed the experiments	Investigation	YES
4399914	25879844	MGB	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Critical revision of the paper for important intellectual content	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399914	25879844	MGB	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Critical revision of the paper for important intellectual content	Critical revision of the paper for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4399914	25879844	SDG	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Critical revision of the paper for important intellectual content	Performed the experiments	Performed the experiments	Investigation	YES
4399914	25879844	SDG	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Critical revision of the paper for important intellectual content	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399914	25879844	SDG	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Critical revision of the paper for important intellectual content	Critical revision of the paper for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5461257	28638397	All the authors	2	discussed the results and contributed to the manuscripts	discussed the results and contributed to the manuscripts	-	-	NO
5461257	28638397	FL	2	help to analyze the ests data	help to analyze the ests data	Analyzed the data	Formal analysis	YES
5461257	28638397	JL	2	help to analyze the ests data	help to analyze the ests data	Analyzed the data	Formal analysis	YES
5461257	28638397	LY	2	analyzed the ests data	analyzed the ests data	Analyzed the data	Formal analysis	YES
5461257	28638397	XH	2	conceived and designed the experiments and performed the cdna clones sequencing experiments|wrote the manuscript	conceived and designed the experiments and performed the cdna clones sequencing experiments	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
5461257	28638397	XH	2	conceived and designed the experiments and performed the cdna clones sequencing experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5461257	28638397	YJ	2	performed the gene expression experiments	performed the gene expression experiments	Performed the experiments	Investigation	YES
5073829	27769162	AYMS	2	authors contributed to the manuscript and approved it for publication	authors contributed to the manuscript and approved it for publication	-	-	NO
5073829	27769162	All	2	authors contributed to the manuscript and approved it for publication	authors contributed to the manuscript and approved it for publication	-	-	NO
5073829	27769162	GDG	2	authors contributed to the manuscript and approved it for publication	authors contributed to the manuscript and approved it for publication	-	-	NO
3833191	24242264	CCM	2	designed and conducted formative research that guided message development and the psychological form and content of the game	designed and conducted formative research that guided message development and the psychological form and content of the game	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Supervision	YES
3833191	24242264	CGG	2	wrote up drafts of sections of the manuscript	wrote up drafts of sections of the manuscript	Wrote the paper	Writing - Original Draft	YES
3833191	24242264	JLC	2	designed and conducted formative research that guided message development and the psychological form and content of the game|worked on conceptualizing shame and how to reduce it|conducted the main statistical analyses with|wrote up drafts of sections of the manuscript	designed and conducted formative research that guided message development and the psychological form and content of the game	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Supervision	YES
3833191	24242264	JLC	2	designed and conducted formative research that guided message development and the psychological form and content of the game|worked on conceptualizing shame and how to reduce it|conducted the main statistical analyses with|wrote up drafts of sections of the manuscript	worked on conceptualizing shame and how to reduce it	Conceived and designed the experiments|Performed the experiments	Conceptualization	YES
3833191	24242264	JLC	2	designed and conducted formative research that guided message development and the psychological form and content of the game|worked on conceptualizing shame and how to reduce it|conducted the main statistical analyses with|wrote up drafts of sections of the manuscript	conducted the main statistical analyses with	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3833191	24242264	JLC	2	designed and conducted formative research that guided message development and the psychological form and content of the game|worked on conceptualizing shame and how to reduce it|conducted the main statistical analyses with|wrote up drafts of sections of the manuscript	wrote up drafts of sections of the manuscript	Wrote the paper	Writing - Original Draft	YES
3833191	24242264	LCM	2	designed and conducted formative research that guided message development and the psychological form and content of the game|worked on conceptualizing shame and how to reduce it|assisted with the conducted the main statistical analyses with|wrote up drafts of sections of the manuscript	designed and conducted formative research that guided message development and the psychological form and content of the game	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Supervision	YES
3833191	24242264	LCM	2	designed and conducted formative research that guided message development and the psychological form and content of the game|worked on conceptualizing shame and how to reduce it|assisted with the conducted the main statistical analyses with|wrote up drafts of sections of the manuscript	worked on conceptualizing shame and how to reduce it	Conceived and designed the experiments|Performed the experiments	Conceptualization	YES
3833191	24242264	LCM	2	designed and conducted formative research that guided message development and the psychological form and content of the game|worked on conceptualizing shame and how to reduce it|assisted with the conducted the main statistical analyses with|wrote up drafts of sections of the manuscript	assisted with the conducted the main statistical analyses with	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3833191	24242264	LCM	2	designed and conducted formative research that guided message development and the psychological form and content of the game|worked on conceptualizing shame and how to reduce it|assisted with the conducted the main statistical analyses with|wrote up drafts of sections of the manuscript	wrote up drafts of sections of the manuscript	Wrote the paper	Writing - Original Draft	YES
3833191	24242264	PRA	2	designed and conducted formative research that guided message development and the psychological form and content of the game|wrote up drafts of sections of the manuscript	designed and conducted formative research that guided message development and the psychological form and content of the game	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Supervision	YES
3833191	24242264	PRA	2	designed and conducted formative research that guided message development and the psychological form and content of the game|wrote up drafts of sections of the manuscript	wrote up drafts of sections of the manuscript	Wrote the paper	Writing - Original Draft	YES
3833191	24242264	SCM	2	designed and conducted formative research that guided message development and the psychological form and content of the game|supervised technical aspects of game and intelligent agent development and animation	designed and conducted formative research that guided message development and the psychological form and content of the game	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Supervision	YES
3833191	24242264	SCM	2	designed and conducted formative research that guided message development and the psychological form and content of the game|supervised technical aspects of game and intelligent agent development and animation	supervised technical aspects of game and intelligent agent development and animation	-	Supervision	YES
3833191	24242264	SJR	2	designed and conducted formative research that guided message development and the psychological form and content of the game	designed and conducted formative research that guided message development and the psychological form and content of the game	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Supervision	YES
3833191	24242264	The authors	2	all designed the study together	all designed the study together	Conceived and designed the experiments	Methodology	YES
4399916	25880065	BRR	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4399916	25880065	DM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399916	25880065	DM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4399916	25880065	DM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4399916	25880065	EBV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399916	25880065	EBV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399916	25880065	EBV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399916	25880065	EBV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399916	25880065	MAC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4399916	25880065	MEM	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4399916	25880065	MM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5871337	29606798	All authors	2	have given approval to the final version of the manuscript	have given approval to the final version of the manuscript	-	-	NO
3109739	21660183	JgS	2	wrote the manuscript|developed the study design and revised the manuscript critically for important intellectual content	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3109739	21660183	JgS	2	wrote the manuscript|developed the study design and revised the manuscript critically for important intellectual content	developed the study design and revised the manuscript critically for important intellectual content	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft|Writing - Review & Editing	YES
3109739	21660183	SMB	2	wrote the manuscript|developed the study design and revised the manuscript critically for important intellectual content	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3109739	21660183	SMB	2	wrote the manuscript|developed the study design and revised the manuscript critically for important intellectual content	developed the study design and revised the manuscript critically for important intellectual content	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft|Writing - Review & Editing	YES
3109739	21660183	WS	2	developed the study design and revised the manuscript critically for important intellectual content	developed the study design and revised the manuscript critically for important intellectual content	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5461258	28638386	AL	2	contributed to metabolite analysis	contributed to metabolite analysis	-	-	NO
5461258	28638386	BW	2	made experiment and finished manuscript	made experiment and finished manuscript	-	-	NO
5461258	28638386	CS	2	were responsible for designing this project as corresponding authors	were responsible for designing this project as corresponding authors	Conceived and designed the experiments	Methodology	YES
5461258	28638386	JY	2	contributed to co-expression analysis	contributed to co-expression analysis	Performed the experiments	Investigation	YES
5461258	28638386	LL	2	contributed to co-expression analysis	contributed to co-expression analysis	Performed the experiments	Investigation	YES
5461258	28638386	LX	2	collected samples	collected samples	Performed the experiments	Investigation	YES
5461258	28638386	SC	2	were responsible for designing this project as corresponding authors	were responsible for designing this project as corresponding authors	Conceived and designed the experiments	Methodology	YES
5461258	28638386	WS	2	made experiment and finished manuscript	made experiment and finished manuscript	-	-	NO
5461258	28638386	WW	2	contributed to metabolite analysis	contributed to metabolite analysis	-	-	NO
5073849	27769165	AAL	PLoS52	conceived the study|designed the study|grew and phenotyped erythroid cells|isolated and prepared rna|performed additional molecular and cell biology experiments|wrote the paper	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5073849	27769165	AAL	PLoS52	conceived the study|designed the study|grew and phenotyped erythroid cells|isolated and prepared rna|performed additional molecular and cell biology experiments|wrote the paper	designed the study	Conceived and designed the experiments	Methodology	YES
5073849	27769165	AAL	PLoS52	conceived the study|designed the study|grew and phenotyped erythroid cells|isolated and prepared rna|performed additional molecular and cell biology experiments|wrote the paper	grew and phenotyped erythroid cells	Performed the experiments	Investigation	YES
5073849	27769165	AAL	PLoS52	conceived the study|designed the study|grew and phenotyped erythroid cells|isolated and prepared rna|performed additional molecular and cell biology experiments|wrote the paper	isolated and prepared rna	Performed the experiments	Investigation	YES
5073849	27769165	AAL	PLoS52	conceived the study|designed the study|grew and phenotyped erythroid cells|isolated and prepared rna|performed additional molecular and cell biology experiments|wrote the paper	performed additional molecular and cell biology experiments	Performed the experiments	Investigation	YES
5073849	27769165	AAL	PLoS52	conceived the study|designed the study|grew and phenotyped erythroid cells|isolated and prepared rna|performed additional molecular and cell biology experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5073849	27769165	AJT	PLoS52	designed the study|grew and phenotyped erythroid cells|analysed microarray data|conducted bioinformatic and genomic analyses|performed additional molecular and cell biology experiments|wrote the paper	designed the study	Conceived and designed the experiments	Methodology	YES
5073849	27769165	AJT	PLoS52	designed the study|grew and phenotyped erythroid cells|analysed microarray data|conducted bioinformatic and genomic analyses|performed additional molecular and cell biology experiments|wrote the paper	grew and phenotyped erythroid cells	Performed the experiments	Investigation	YES
5073849	27769165	AJT	PLoS52	designed the study|grew and phenotyped erythroid cells|analysed microarray data|conducted bioinformatic and genomic analyses|performed additional molecular and cell biology experiments|wrote the paper	analysed microarray data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5073849	27769165	AJT	PLoS52	designed the study|grew and phenotyped erythroid cells|analysed microarray data|conducted bioinformatic and genomic analyses|performed additional molecular and cell biology experiments|wrote the paper	conducted bioinformatic and genomic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5073849	27769165	AJT	PLoS52	designed the study|grew and phenotyped erythroid cells|analysed microarray data|conducted bioinformatic and genomic analyses|performed additional molecular and cell biology experiments|wrote the paper	performed additional molecular and cell biology experiments	Performed the experiments	Investigation	YES
5073849	27769165	AJT	PLoS52	designed the study|grew and phenotyped erythroid cells|analysed microarray data|conducted bioinformatic and genomic analyses|performed additional molecular and cell biology experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5073849	27769165	AKN	PLoS52	conceived the study|designed clustering algorithms and carried out computational clustering analyses	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5073849	27769165	AKN	PLoS52	conceived the study|designed clustering algorithms and carried out computational clustering analyses	designed clustering algorithms and carried out computational clustering analyses	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Software	YES
5073849	27769165	ATMC	PLoS52	conceived the study|designed the study|grew and phenotyped erythroid cells|isolated and prepared rna|processed rna, prepared target and hybridised microarrays, and pre-processed and normalised microarray data|analysed microarray data|conducted bioinformatic and genomic analyses|performed additional molecular and cell biology experiments|wrote the paper	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5073849	27769165	ATMC	PLoS52	conceived the study|designed the study|grew and phenotyped erythroid cells|isolated and prepared rna|processed rna, prepared target and hybridised microarrays, and pre-processed and normalised microarray data|analysed microarray data|conducted bioinformatic and genomic analyses|performed additional molecular and cell biology experiments|wrote the paper	designed the study	Conceived and designed the experiments	Methodology	YES
5073849	27769165	ATMC	PLoS52	conceived the study|designed the study|grew and phenotyped erythroid cells|isolated and prepared rna|processed rna, prepared target and hybridised microarrays, and pre-processed and normalised microarray data|analysed microarray data|conducted bioinformatic and genomic analyses|performed additional molecular and cell biology experiments|wrote the paper	grew and phenotyped erythroid cells	Performed the experiments	Investigation	YES
5073849	27769165	ATMC	PLoS52	conceived the study|designed the study|grew and phenotyped erythroid cells|isolated and prepared rna|processed rna, prepared target and hybridised microarrays, and pre-processed and normalised microarray data|analysed microarray data|conducted bioinformatic and genomic analyses|performed additional molecular and cell biology experiments|wrote the paper	isolated and prepared rna	Performed the experiments	Investigation	YES
5073849	27769165	ATMC	PLoS52	conceived the study|designed the study|grew and phenotyped erythroid cells|isolated and prepared rna|processed rna, prepared target and hybridised microarrays, and pre-processed and normalised microarray data|analysed microarray data|conducted bioinformatic and genomic analyses|performed additional molecular and cell biology experiments|wrote the paper	processed rna, prepared target and hybridised microarrays, and pre-processed and normalised microarray data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5073849	27769165	ATMC	PLoS52	conceived the study|designed the study|grew and phenotyped erythroid cells|isolated and prepared rna|processed rna, prepared target and hybridised microarrays, and pre-processed and normalised microarray data|analysed microarray data|conducted bioinformatic and genomic analyses|performed additional molecular and cell biology experiments|wrote the paper	analysed microarray data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5073849	27769165	ATMC	PLoS52	conceived the study|designed the study|grew and phenotyped erythroid cells|isolated and prepared rna|processed rna, prepared target and hybridised microarrays, and pre-processed and normalised microarray data|analysed microarray data|conducted bioinformatic and genomic analyses|performed additional molecular and cell biology experiments|wrote the paper	conducted bioinformatic and genomic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5073849	27769165	ATMC	PLoS52	conceived the study|designed the study|grew and phenotyped erythroid cells|isolated and prepared rna|processed rna, prepared target and hybridised microarrays, and pre-processed and normalised microarray data|analysed microarray data|conducted bioinformatic and genomic analyses|performed additional molecular and cell biology experiments|wrote the paper	performed additional molecular and cell biology experiments	Performed the experiments	Investigation	YES
5073849	27769165	ATMC	PLoS52	conceived the study|designed the study|grew and phenotyped erythroid cells|isolated and prepared rna|processed rna, prepared target and hybridised microarrays, and pre-processed and normalised microarray data|analysed microarray data|conducted bioinformatic and genomic analyses|performed additional molecular and cell biology experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5073849	27769165	BAJ	PLoS52	analysed microarray data|conducted bioinformatic and genomic analyses|designed clustering algorithms and carried out computational clustering analyses	analysed microarray data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5073849	27769165	BAJ	PLoS52	analysed microarray data|conducted bioinformatic and genomic analyses|designed clustering algorithms and carried out computational clustering analyses	conducted bioinformatic and genomic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5073849	27769165	BAJ	PLoS52	analysed microarray data|conducted bioinformatic and genomic analyses|designed clustering algorithms and carried out computational clustering analyses	designed clustering algorithms and carried out computational clustering analyses	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Software	YES
5073849	27769165	DJR	PLoS52	conceived the study|designed the study|wrote the paper	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5073849	27769165	DJR	PLoS52	conceived the study|designed the study|wrote the paper	designed the study	Conceived and designed the experiments	Methodology	YES
5073849	27769165	DJR	PLoS52	conceived the study|designed the study|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5073849	27769165	HPT	PLoS52	grew and phenotyped erythroid cells|isolated and prepared rna|performed additional molecular and cell biology experiments	grew and phenotyped erythroid cells	Performed the experiments	Investigation	YES
5073849	27769165	HPT	PLoS52	grew and phenotyped erythroid cells|isolated and prepared rna|performed additional molecular and cell biology experiments	isolated and prepared rna	Performed the experiments	Investigation	YES
5073849	27769165	HPT	PLoS52	grew and phenotyped erythroid cells|isolated and prepared rna|performed additional molecular and cell biology experiments	performed additional molecular and cell biology experiments	Performed the experiments	Investigation	YES
5073849	27769165	KJHR	PLoS52	conceived the study|designed the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5073849	27769165	KJHR	PLoS52	conceived the study|designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5073849	27769165	RF	PLoS52	analysed microarray data|conducted bioinformatic and genomic analyses|designed clustering algorithms and carried out computational clustering analyses	analysed microarray data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5073849	27769165	RF	PLoS52	analysed microarray data|conducted bioinformatic and genomic analyses|designed clustering algorithms and carried out computational clustering analyses	conducted bioinformatic and genomic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5073849	27769165	RF	PLoS52	analysed microarray data|conducted bioinformatic and genomic analyses|designed clustering algorithms and carried out computational clustering analyses	designed clustering algorithms and carried out computational clustering analyses	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Software	YES
5073849	27769165	all authors	PLoS52	discussed and reviewed data|reviewed and edited the paper	discussed and reviewed data	-	-	NO
5073849	27769165	all authors	PLoS52	discussed and reviewed data|reviewed and edited the paper	reviewed and edited the paper	Wrote the paper	Writing - Review & Editing	YES
5461261	28638389	AC	7	performed greenhouse measurements, data analysis, and writing the manuscript	performed greenhouse measurements, data analysis, and writing the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5461261	28638389	AK	7	support in data analysis and writing	support in data analysis and writing	Analyzed the data|Wrote the paper	Formal analysis	YES
5461261	28638389	HE	7	head of the lab on parasitic weeds	head of the lab on parasitic weeds	Performed the experiments	Investigation	YES
5461261	28638389	JE	7	support in data analysis and writing	support in data analysis and writing	Analyzed the data|Wrote the paper	Formal analysis	YES
5461261	28638389	SR	7	support in data analysis and writing	support in data analysis and writing	Analyzed the data|Wrote the paper	Formal analysis	YES
5461261	28638389	TG	7	performed anatomic cross-sections	performed anatomic cross-sections	Performed the experiments	Investigation	YES
5461261	28638389	TR	7	performed greenhouse spectral measurements and pls-r analysis	performed greenhouse spectral measurements and pls-r analysis	Performed the experiments	Investigation	YES
3833192	24242259	CBT	PLoS52	have all contributed equally|conceptualized and designed the study|collected the data|edited and contributed to further development/writing this article	have all contributed equally	-	-	NO
3833192	24242259	CBT	PLoS52	have all contributed equally|conceptualized and designed the study|collected the data|edited and contributed to further development/writing this article	conceptualized and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3833192	24242259	CBT	PLoS52	have all contributed equally|conceptualized and designed the study|collected the data|edited and contributed to further development/writing this article	collected the data	Performed the experiments	Investigation	YES
3833192	24242259	CBT	PLoS52	have all contributed equally|conceptualized and designed the study|collected the data|edited and contributed to further development/writing this article	edited and contributed to further development/writing this article	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3833192	24242259	EM	PLoS52	have all contributed equally|collected the data|analyzed the data|were responsible for writing the first draft of this article	have all contributed equally	-	-	NO
3833192	24242259	EM	PLoS52	have all contributed equally|collected the data|analyzed the data|were responsible for writing the first draft of this article	collected the data	Performed the experiments	Investigation	YES
3833192	24242259	EM	PLoS52	have all contributed equally|collected the data|analyzed the data|were responsible for writing the first draft of this article	analyzed the data	Analyzed the data	Formal analysis	YES
3833192	24242259	EM	PLoS52	have all contributed equally|collected the data|analyzed the data|were responsible for writing the first draft of this article	were responsible for writing the first draft of this article	Wrote the paper	Writing - Original Draft	YES
3833192	24242259	JBP	PLoS52	conceptualized and designed the study|collected the data|were responsible for writing the first draft of this article	conceptualized and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3833192	24242259	JBP	PLoS52	conceptualized and designed the study|collected the data|were responsible for writing the first draft of this article	collected the data	Performed the experiments	Investigation	YES
3833192	24242259	JBP	PLoS52	conceptualized and designed the study|collected the data|were responsible for writing the first draft of this article	were responsible for writing the first draft of this article	Wrote the paper	Writing - Original Draft	YES
3833192	24242259	MB	PLoS52	have all contributed equally|collected the data|analyzed the data|were responsible for writing the first draft of this article	have all contributed equally	-	-	NO
3833192	24242259	MB	PLoS52	have all contributed equally|collected the data|analyzed the data|were responsible for writing the first draft of this article	collected the data	Performed the experiments	Investigation	YES
3833192	24242259	MB	PLoS52	have all contributed equally|collected the data|analyzed the data|were responsible for writing the first draft of this article	analyzed the data	Analyzed the data	Formal analysis	YES
3833192	24242259	MB	PLoS52	have all contributed equally|collected the data|analyzed the data|were responsible for writing the first draft of this article	were responsible for writing the first draft of this article	Wrote the paper	Writing - Original Draft	YES
3833192	24242259	SDS	PLoS52	have all contributed equally	have all contributed equally	-	-	NO
3833192	24242259	SH	PLoS52	collected the data|provided additional edits for this article	collected the data	Performed the experiments	Investigation	YES
3833192	24242259	SH	PLoS52	collected the data|provided additional edits for this article	provided additional edits for this article	Wrote the paper	Writing - Review & Editing	YES
3833192	24242259	SS	PLoS52	analyzed the data|edited and contributed to further development/writing this article	analyzed the data	Analyzed the data	Formal analysis	YES
3833192	24242259	SS	PLoS52	analyzed the data|edited and contributed to further development/writing this article	edited and contributed to further development/writing this article	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3833192	24242259	TS	PLoS52	collected the data|were responsible for writing the first draft of this article	collected the data	Performed the experiments	Investigation	YES
3833192	24242259	TS	PLoS52	collected the data|were responsible for writing the first draft of this article	were responsible for writing the first draft of this article	Wrote the paper	Writing - Original Draft	YES
3833192	24242259	The authors	PLoS52	have all contributed equally	have all contributed equally	-	-	NO
3833192	24242259	YJB-P	PLoS52	have all contributed equally	have all contributed equally	-	-	NO
5298009	27670755	Both authors	2	participated in revising the manuscript and approving the final version	participated in revising the manuscript and approving the final version	Wrote the paper	Writing - Review & Editing	YES
5298009	27670755	GR	2	contributed to the conception of the study, designed the study, performed statistical analyses, and drafted the manuscript	contributed to the conception of the study, designed the study, performed statistical analyses, and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
5298009	27670755	LS	2	contributed to the design of the study and to statistical analyses	contributed to the design of the study and to statistical analyses	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
4399920	25880079	TAS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399920	25880079	TAS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399920	25880079	TAS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399920	25880079	TAS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399920	25880079	TAS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5871342	29606797	All authors	2	have given approval to the final version of the manuscript	have given approval to the final version of the manuscript	-	-	NO
5073857	27766955	EA	2	were involved in the web interface creation, tested the web interface and provided feedback	were involved in the web interface creation, tested the web interface and provided feedback	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5073857	27766955	HA	2	were involved in the web interface creation, tested the web interface and provided feedback	were involved in the web interface creation, tested the web interface and provided feedback	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5073857	27766955	HN	2	were involved in the web interface creation, tested the web interface and provided feedback	were involved in the web interface creation, tested the web interface and provided feedback	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5073857	27766955	JD	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5073857	27766955	LBS	2	were involved in the web interface creation, tested the web interface and provided feedback|wrote the manuscript	were involved in the web interface creation, tested the web interface and provided feedback	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5073857	27766955	LBS	2	were involved in the web interface creation, tested the web interface and provided feedback|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5073857	27766955	MS	2	performed data collection and designed and constructed the database|wrote the manuscript	performed data collection and designed and constructed the database	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5073857	27766955	MS	2	performed data collection and designed and constructed the database|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5073857	27766955	NS	2	were involved in the web interface creation, tested the web interface and provided feedback	were involved in the web interface creation, tested the web interface and provided feedback	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5073857	27766955	SKareem	2	guided the development of the web interface|wrote the manuscript	guided the development of the web interface	Contributed reagents/materials/analysis tools	Software|Supervision	YES
5073857	27766955	SKareem	2	guided the development of the web interface|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5073857	27766955	SKumar	2	conceived the project|guided the development of the web interface|wrote the manuscript	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5073857	27766955	SKumar	2	conceived the project|guided the development of the web interface|wrote the manuscript	guided the development of the web interface	Contributed reagents/materials/analysis tools	Software|Supervision	YES
5073857	27766955	SKumar	2	conceived the project|guided the development of the web interface|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5347861	27804174	C. Harvey	2	reviewed all safety data in-stream and adapted the protocol for collection of additional details and analysis of events of pneumonia	reviewed all safety data in-stream and adapted the protocol for collection of additional details and analysis of events of pneumonia	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5347861	27804174	C. Williams	2	was involved in streamlining and improving safety processes, including the creation of the safety alert form and new ways of working for the safety nurse team	was involved in streamlining and improving safety processes, including the creation of the safety alert form and new ways of working for the safety nurse team	-	-	NO
5347861	27804174	D. Leather	2	conceived the concept for the trial and was involved in setting up the salford lung study and approval of the paper	conceived the concept for the trial and was involved in setting up the salford lung study and approval of the paper	Conceived and designed the experiments|Performed the experiments	Conceptualization|Methodology	YES
5347861	27804174	H. F. Elkhenini	2	was the safety physician in the studies|was involved in developing the clinical safety alerts, safety monitoring process, testing of the system, discussion about the paper, writing and review	was the safety physician in the studies	-	-	NO
5347861	27804174	H. F. Elkhenini	2	was the safety physician in the studies|was involved in developing the clinical safety alerts, safety monitoring process, testing of the system, discussion about the paper, writing and review	was involved in developing the clinical safety alerts, safety monitoring process, testing of the system, discussion about the paper, writing and review	Performed the experiments|Wrote the paper	Investigation|Methodology|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
5347861	27804174	J. Brereton	2	led the implementation of primary and secondary care safety process and supported the transition of both primary and secondary sites	led the implementation of primary and secondary care safety process and supported the transition of both primary and secondary sites	Performed the experiments	Investigation	YES
5347861	27804174	J. Brewster	2	was involved in developing safety processes and in collection and review of sae data into the safety database	was involved in developing safety processes and in collection and review of sae data into the safety database	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Investigation|Software	YES
5347861	27804174	J. Crae	2	led the implementation of the it infrastructure in the salford lung study and was involved in the initial writing of paper and subsequent review	led the implementation of the it infrastructure in the salford lung study and was involved in the initial writing of paper and subsequent review	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5347861	27804174	R. Stanciu	2	participated in developing the collection form for pneumonia and the testing of the alerts system in secondary care|contributed to writing and review	participated in developing the collection form for pneumonia and the testing of the alerts system in secondary care	Performed the experiments	Investigation|Methodology	YES
5347861	27804174	R. Stanciu	2	participated in developing the collection form for pneumonia and the testing of the alerts system in secondary care|contributed to writing and review	contributed to writing and review	Wrote the paper	Writing - Review & Editing	YES
5347861	27804174	S. Corkindale	2	as the gp representative, was involved in discussions about the development of safety alerts and initial discussion about the paper and review	as the gp representative, was involved in discussions about the development of safety alerts and initial discussion about the paper and review	Wrote the paper	Writing - Original Draft	YES
5347861	27804174	Salford Lung Study	2	developing the clinical safety alerts, the initial discussion about the paper and subsequent review|the initial writing of paper and subsequent review	developing the clinical safety alerts, the initial discussion about the paper and subsequent review	Wrote the paper	Writing - Original Draft	YES
5347861	27804174	Salford Lung Study	2	developing the clinical safety alerts, the initial discussion about the paper and subsequent review|the initial writing of paper and subsequent review	the initial writing of paper and subsequent review	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3833193	24242265	EH	2	conducted the data analyses presented in this article and prepared the tables	conducted the data analyses presented in this article and prepared the tables	Analyzed the data	Formal analysis	YES
3833193	24242265	JR	2	collaborated on the design of the study as well as the collection and interpretation of data|read the article and provided critical feedback	collaborated on the design of the study as well as the collection and interpretation of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
3833193	24242265	JR	2	collaborated on the design of the study as well as the collection and interpretation of data|read the article and provided critical feedback	read the article and provided critical feedback	-	-	NO
3833193	24242265	ME	2	collaborated on the design of the study as well as the collection and interpretation of data	collaborated on the design of the study as well as the collection and interpretation of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
3833193	24242265	SB	2	collaborated on the design of the study as well as the collection and interpretation of data|read the article and provided critical feedback	collaborated on the design of the study as well as the collection and interpretation of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
3833193	24242265	SB	2	collaborated on the design of the study as well as the collection and interpretation of data|read the article and provided critical feedback	read the article and provided critical feedback	-	-	NO
4399934	25880200	JB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399934	25880200	JB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399934	25880200	JB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399934	25880200	JB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399934	25880200	KG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399934	25880200	KG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399934	25880200	KG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399934	25880200	KG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399934	25880200	KG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5461291	28638396	All authors	2	agreed on the final version of the manuscript	agreed on the final version of the manuscript	-	-	NO
5461291	28638396	HR	2	contributed the irms analyses and ideas to the study and the manuscript	contributed the irms analyses and ideas to the study and the manuscript	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
5461291	28638396	The authors	2	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	Performed the experiments	Investigation	YES
5073859	27766952	All authors	2	contributed to the writing up and revision of the manuscript	contributed to the writing up and revision of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4399936	25879203	PL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4399936	25879203	PL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399936	25879203	ZCS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4399936	25879203	ZHL	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399936	25879203	ZHL	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5461292	28638394	AB	7	Instrumental in the preparation of samples for tem analysis	Instrumental in the preparation of samples for tem analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5461292	28638394	BN	7	provided lab infrastructure and funding in support of the experimental worked performed, in particular the amino acid analyses costs, and extensive editing and scientific input into the preparation of the final manuscript	provided lab infrastructure and funding in support of the experimental worked performed, in particular the amino acid analyses costs, and extensive editing and scientific input into the preparation of the final manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Funding acquisition|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5461292	28638394	JeK	7	provided lab infrastructure and funding in support of the experimental work performed at Stellenbosch	provided lab infrastructure and funding in support of the experimental work performed at Stellenbosch	Performed the experiments	Funding acquisition|Investigation	YES
5461292	28638394	JoK	7	Responsible for the anti-nutrient experiments, gave scientific input on the structure and form of the manuscript, edited as necessary	Responsible for the anti-nutrient experiments, gave scientific input on the structure and form of the manuscript, edited as necessary	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5461292	28638394	LM	7	Provided access to the gm material, grew the plants at the containment facility, collected the samples, prepared material for the experiments, gave scientific input into the structure and form of the manuscript	Provided access to the gm material, grew the plants at the containment facility, collected the samples, prepared material for the experiments, gave scientific input into the structure and form of the manuscript	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Resources|Writing - Original Draft	YES
5461292	28638394	RN	7	Carried out the bulk of the experimental work, compiled the results, drafted the manuscript	Carried out the bulk of the experimental work, compiled the results, drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6204570	30027754	A.F.Y.P.	3	Planning of analyses	Planning of analyses	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
6204570	30027754	A.M.D.	3	Planning of analyses|Data assembly and review|Phylogenetic analyses|Statistical analyses|Drafting article	Planning of analyses	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
6204570	30027754	A.M.D.	3	Planning of analyses|Data assembly and review|Phylogenetic analyses|Statistical analyses|Drafting article	Data assembly and review	-	-	NO
6204570	30027754	A.M.D.	3	Planning of analyses|Data assembly and review|Phylogenetic analyses|Statistical analyses|Drafting article	Phylogenetic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6204570	30027754	A.M.D.	3	Planning of analyses|Data assembly and review|Phylogenetic analyses|Statistical analyses|Drafting article	Statistical analyses	Analyzed the data	Formal analysis	YES
6204570	30027754	A.M.D.	3	Planning of analyses|Data assembly and review|Phylogenetic analyses|Statistical analyses|Drafting article	Drafting article	Wrote the paper	Writing - Original Draft	YES
6204570	30027754	A.S.M.M.H.	3	Data assembly and review	Data assembly and review	-	-	NO
6204570	30027754	E.V.	3	Planning of analyses|Phylodynamic analyses|Statistical analyses|Drafting article	Planning of analyses	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
6204570	30027754	E.V.	3	Planning of analyses|Phylodynamic analyses|Statistical analyses|Drafting article	Phylodynamic analyses	Analyzed the data	Formal analysis	YES
6204570	30027754	E.V.	3	Planning of analyses|Phylodynamic analyses|Statistical analyses|Drafting article	Statistical analyses	Analyzed the data	Formal analysis	YES
6204570	30027754	E.V.	3	Planning of analyses|Phylodynamic analyses|Statistical analyses|Drafting article	Drafting article	Wrote the paper	Writing - Original Draft	YES
6204570	30027754	M.L.K.	3	Planning of analyses|Securing grant funding and specimens	Planning of analyses	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
6204570	30027754	M.L.K.	3	Planning of analyses|Securing grant funding and specimens	Securing grant funding and specimens	Performed the experiments	Funding acquisition|Investigation	YES
6204570	30027754	P.F.R.	3	Data assembly and review|Securing grant funding and specimens	Data assembly and review	-	-	NO
6204570	30027754	P.F.R.	3	Data assembly and review|Securing grant funding and specimens	Securing grant funding and specimens	Performed the experiments	Funding acquisition|Investigation	YES
6204570	30027754	S.D.W.F.	3	Planning of analyses|Data assembly and review|Phylogenetic analyses|Drafting article	Planning of analyses	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
6204570	30027754	S.D.W.F.	3	Planning of analyses|Data assembly and review|Phylogenetic analyses|Drafting article	Data assembly and review	-	-	NO
6204570	30027754	S.D.W.F.	3	Planning of analyses|Data assembly and review|Phylogenetic analyses|Drafting article	Phylogenetic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6204570	30027754	S.D.W.F.	3	Planning of analyses|Data assembly and review|Phylogenetic analyses|Drafting article	Drafting article	Wrote the paper	Writing - Original Draft	YES
6204570	30027754	S.H.V.	3	Securing grant funding and specimens	Securing grant funding and specimens	Performed the experiments	Funding acquisition|Investigation	YES
6204570	30027754	T.R.S.	3	Securing grant funding and specimens	Securing grant funding and specimens	Performed the experiments	Funding acquisition|Investigation	YES
6204570	30027754	all authors	3	And article review and edit	And article review and edit	Wrote the paper	Writing - Review & Editing	YES
5073890	27769168	AA	2	performed specialized analysis of whole genome assemblies	performed specialized analysis of whole genome assemblies	Performed the experiments	Investigation	YES
5073890	27769168	AME	2	participated in the design of the study and oversaw sequencing and primary analysis of genomic data	participated in the design of the study and oversaw sequencing and primary analysis of genomic data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology|Supervision	YES
5073890	27769168	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5073890	27769168	CD	2	conceived of the strategy of data analysis, participated in analysis and in coordination and drafted the manuscript	conceived of the strategy of data analysis, participated in analysis and in coordination and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Project administration|Writing - Original Draft	YES
5073890	27769168	JCM	2	performed laboratory experiments|participated in the design of this study and helped to draft the manuscript	performed laboratory experiments	Performed the experiments	Investigation	YES
5073890	27769168	JCM	2	performed laboratory experiments|participated in the design of this study and helped to draft the manuscript	participated in the design of this study and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5073890	27769168	PD	2	performed the sequence analyses and helped to draft the manuscript	performed the sequence analyses and helped to draft the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5073890	27769168	TL	2	performed laboratory experiments|participated in the design of this study and helped to draft the manuscript	performed laboratory experiments	Performed the experiments	Investigation	YES
5073890	27769168	TL	2	performed laboratory experiments|participated in the design of this study and helped to draft the manuscript	participated in the design of this study and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4427062	26000288	Jhih-Wei Huang	2	contributed equally to the work	contributed equally to the work	-	-	NO
4427062	26000288	Tzu-Ching Sung	2	contributed equally to the work	contributed equally to the work	-	-	NO
5973779	29861547	J.A.B.	2	contributed equally	contributed equally	-	-	NO
5973779	29861547	J.T.	2	contributed equally	contributed equally	-	-	NO
4399937	25880904	AG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399937	25880904	AG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399937	25880904	AG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399937	25880904	AG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399937	25880904	CGG	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399937	25880904	CGG	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399937	25880904	CGG	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399937	25880904	CGG	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399937	25880904	DE	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399937	25880904	DE	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399937	25880904	DE	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399937	25880904	DE	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399937	25880904	DWW	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399937	25880904	DWW	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399937	25880904	DWW	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399937	25880904	DWW	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399937	25880904	KK	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399937	25880904	RG	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399937	25880904	SL	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399937	25880904	SL	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399937	25880904	SL	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399937	25880904	SSA	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399937	25880904	SSA	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5461294	28638390	FY	PLoS52	analyzed the results	analyzed the results	Analyzed the data	Formal analysis	YES
5461294	28638390	JW	PLoS52	designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
5461294	28638390	LL	PLoS52	performed the experiments|analyzed the results	performed the experiments	Performed the experiments	Investigation	YES
5461294	28638390	LL	PLoS52	performed the experiments|analyzed the results	analyzed the results	Analyzed the data	Formal analysis	YES
5461294	28638390	MZ	PLoS52	analyzed the results|wrote and revised the manuscript, and all authors read and approved the final manuscript	analyzed the results	Analyzed the data	Formal analysis	YES
5461294	28638390	MZ	PLoS52	analyzed the results|wrote and revised the manuscript, and all authors read and approved the final manuscript	wrote and revised the manuscript, and all authors read and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5461294	28638390	RC	PLoS52	analyzed the results	analyzed the results	Analyzed the data	Formal analysis	YES
5461294	28638390	XH	PLoS52	performed the experiments|analyzed the results	performed the experiments	Performed the experiments	Investigation	YES
5461294	28638390	XH	PLoS52	performed the experiments|analyzed the results	analyzed the results	Analyzed the data	Formal analysis	YES
5461294	28638390	YH	PLoS52	designed the research|performed the experiments|analyzed the results|wrote and revised the manuscript, and all authors read and approved the final manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
5461294	28638390	YH	PLoS52	designed the research|performed the experiments|analyzed the results|wrote and revised the manuscript, and all authors read and approved the final manuscript	performed the experiments	Performed the experiments	Investigation	YES
5461294	28638390	YH	PLoS52	designed the research|performed the experiments|analyzed the results|wrote and revised the manuscript, and all authors read and approved the final manuscript	analyzed the results	Analyzed the data	Formal analysis	YES
5461294	28638390	YH	PLoS52	designed the research|performed the experiments|analyzed the results|wrote and revised the manuscript, and all authors read and approved the final manuscript	wrote and revised the manuscript, and all authors read and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5461294	28638390	YY	PLoS52	analyzed the results	analyzed the results	Analyzed the data	Formal analysis	YES
5461294	28638390	ZD	PLoS52	designed the research|wrote and revised the manuscript, and all authors read and approved the final manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
5461294	28638390	ZD	PLoS52	designed the research|wrote and revised the manuscript, and all authors read and approved the final manuscript	wrote and revised the manuscript, and all authors read and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5485080	28370746	Both authors	2	participated in revising the manuscript and approving the final version	participated in revising the manuscript and approving the final version	Wrote the paper	Writing - Review & Editing	YES
5485080	28370746	G.R.	2	contributed to the conception of the study, designed the study, performed statistical analyses and drafted the manuscript	contributed to the conception of the study, designed the study, performed statistical analyses and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
5485080	28370746	L.S.	2	contributed to the design of the study and to statistical analyses	contributed to the design of the study and to statistical analyses	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5073903	27766947	AB	2	wrote the first draft of the manuscript and was responsible for the genetic analysis, the statistical analysis and interpretation of the data	wrote the first draft of the manuscript and was responsible for the genetic analysis, the statistical analysis and interpretation of the data	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5073903	27766947	FHB	2	contributed to the original data collection	contributed to the original data collection	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5073903	27766947	FJ	2	contributed to the biological and immunoassay	contributed to the biological and immunoassay	Performed the experiments	Investigation	YES
5073903	27766947	FM	2	contributed to the biological and immunoassay	contributed to the biological and immunoassay	Performed the experiments	Investigation	YES
5073903	27766947	MA	2	contributed to the original data collection|have read the manuscript, revised it, agreed that the work is ready for publication	contributed to the original data collection	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5073903	27766947	MA	2	contributed to the original data collection|have read the manuscript, revised it, agreed that the work is ready for publication	have read the manuscript, revised it, agreed that the work is ready for publication	Wrote the paper	Writing - Review & Editing	YES
5073903	27766947	MAE	2	have read the manuscript, revised it, agreed that the work is ready for publication	have read the manuscript, revised it, agreed that the work is ready for publication	Wrote the paper	Writing - Review & Editing	YES
5073903	27766947	MHAQ	2	have read the manuscript, revised it, agreed that the work is ready for publication	have read the manuscript, revised it, agreed that the work is ready for publication	Wrote the paper	Writing - Review & Editing	YES
5073903	27766947	MS	2	contributed to the biological and immunoassay	contributed to the biological and immunoassay	Performed the experiments	Investigation	YES
5073903	27766947	OK	2	contributed to the original data collection	contributed to the original data collection	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5073903	27766947	SH	2	contributed to the biological and immunoassay	contributed to the biological and immunoassay	Performed the experiments	Investigation	YES
5073903	27766947	TM	2	initiated and designed the study, and is responsible for the facility in which the study is conducted	initiated and designed the study, and is responsible for the facility in which the study is conducted	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
4427084	26000292	Guang Yang	2	contributed equally to this work	contributed equally to this work	-	-	NO
4427084	26000292	Lu Gao	2	contributed equally to this work	contributed equally to this work	-	-	NO
4427084	26000292	Minjie Gao	2	contributed equally to this work	contributed equally to this work	-	-	NO
4399938	25879210	GA	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399938	25879210	H. Kanetaka	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399938	25879210	H. Kanetaka	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399938	25879210	H. Kanetaka	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399938	25879210	H. Kosukegawa	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399938	25879210	HM	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4399938	25879210	K. Mochizuki	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399938	25879210	K. Mori	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399938	25879210	KT	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4399938	25879210	KT	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4399938	25879210	SI	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399938	25879210	SI	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399938	25879210	SN	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4399938	25879210	SN	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4399938	25879210	TA	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4399938	25879210	TK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399938	25879210	TK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399938	25879210	TK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399938	25879210	TK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399938	25879210	TK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399938	25879210	TT	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5461296	28638391	GY	2	carried out experiments	carried out experiments	Performed the experiments	Investigation	YES
5461296	28638391	HQ	2	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5461296	28638391	LH	2	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5461296	28638391	MC	2	analyzed data|completed the manuscript|designed the experiments	analyzed data	Analyzed the data	Formal analysis	YES
5461296	28638391	MC	2	analyzed data|completed the manuscript|designed the experiments	completed the manuscript	-	-	NO
5461296	28638391	MC	2	analyzed data|completed the manuscript|designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5461296	28638391	PL	2	carried out experiments	carried out experiments	Performed the experiments	Investigation	YES
5461296	28638391	XZ	2	carried out experiments	carried out experiments	Performed the experiments	Investigation	YES
5461296	28638391	YS	2	carried out experiments	carried out experiments	Performed the experiments	Investigation	YES
5461296	28638391	ZC	2	completed the manuscript|designed the experiments	completed the manuscript	-	-	NO
5461296	28638391	ZC	2	completed the manuscript|designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5516175	28266092	All authors	2	participated in the design or implementation or analysis, and interpretation of the study and in the development of this manuscript|had full access to the data and gave final approval before submission	participated in the design or implementation or analysis, and interpretation of the study and in the development of this manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5516175	28266092	All authors	2	participated in the design or implementation or analysis, and interpretation of the study and in the development of this manuscript|had full access to the data and gave final approval before submission	had full access to the data and gave final approval before submission	-	-	NO
6434599	30585733	A.T.	2	performed the analysis on the ectocervical tissue samples, participated in the overall data analysis, and wrote the article	performed the analysis on the ectocervical tissue samples, participated in the overall data analysis, and wrote the article	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6434599	30585733	G.B.-L.	2	performed experiments and data analyses	performed experiments and data analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6434599	30585733	G.E.	2	performed experiments and data analyses	performed experiments and data analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6434599	30585733	J.C.	2	was the clinical coordinator	was the clinical coordinator	-	Project administration	YES
6434599	30585733	J.K.	2	managed the clinical cohort	managed the clinical cohort	-	-	NO
6434599	30585733	J.L.	2	participated in the study design, acted as the study coordinator, performed analyses, and wrote the article	participated in the study design, acted as the study coordinator, performed analyses, and wrote the article	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Project administration|Writing - Original Draft	YES
6434599	30585733	K.B.	2	were the principal investigators of the study and wrote the article	were the principal investigators of the study and wrote the article	Conceived and designed the experiments|Wrote the paper	Conceptualization|Funding acquisition|Writing - Original Draft	YES
6434599	30585733	K.O.	2	performed some of the flow cytometry experiments	performed some of the flow cytometry experiments	Performed the experiments	Investigation	YES
6434599	30585733	K.R.F.	2	were the principal investigators of the study and wrote the article	were the principal investigators of the study and wrote the article	Conceived and designed the experiments|Wrote the paper	Conceptualization|Funding acquisition|Writing - Original Draft	YES
6434599	30585733	M.K.	2	was the medical doctor who proceeded and supervised the collection of samples	was the medical doctor who proceeded and supervised the collection of samples	Performed the experiments	Investigation|Supervision	YES
6434599	30585733	M.R.	2	performed experiments and data analyses	performed experiments and data analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4427085	26000286	Catia Duarte	2	has done data collection, critical revision, and final approval of the paper	has done data collection, critical revision, and final approval of the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4427085	26000286	Claudia Miguel	2	has done data collection, critical revision, and final approval of the paper	has done data collection, critical revision, and final approval of the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4427085	26000286	Fernando M. Pimentel-Santos	2	has done data collection, critical revision, and final approval of the paper	has done data collection, critical revision, and final approval of the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4427085	26000286	Filipe Barcelos	2	has done data collection, critical revision, and final approval of the paper	has done data collection, critical revision, and final approval of the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4427085	26000286	Helena Canhao	2	has done study conception and design, data collection, data and statistical analysis, paper drafting, critical revision, and final approval of paper	has done study conception and design, data collection, data and statistical analysis, paper drafting, critical revision, and final approval of paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
4427085	26000286	Jaime Cunha Branco	2	has done data collection, critical revision, and final approval of the paper	has done data collection, critical revision, and final approval of the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4427085	26000286	Joao Eurico Fonseca	2	has done study conception and design, data collection, data analysis, paper drafting, critical revision, and final approval of paper	has done study conception and design, data collection, data analysis, paper drafting, critical revision, and final approval of paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
4427085	26000286	Joaquim Polido-Pereira	2	has done data collection, critical revision, and final approval of the paper	has done data collection, critical revision, and final approval of the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4427085	26000286	Jose Antonio Costa	2	has done data collection, critical revision, and final approval of the paper	has done data collection, critical revision, and final approval of the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4427085	26000286	Jose Antonio Melo	2	has done data collection, critical revision, and final approval of the paper	has done data collection, critical revision, and final approval of the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4427085	26000286	Lucia Costa	2	has done data collection, critical revision, and final approval of the paper	has done data collection, critical revision, and final approval of the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4427085	26000286	Maria Jose Santos	2	has done data collection, critical revision, and final approval of the paper	has done data collection, critical revision, and final approval of the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4427085	26000286	Miguel Bernardes	2	has done data collection, critical revision, and final approval of the paper	has done data collection, critical revision, and final approval of the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4427085	26000286	Patricia Nero	2	has done data collection, critical revision, and final approval of the paper	has done data collection, critical revision, and final approval of the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4427085	26000286	Vasco C. Romao	2	has done study conception and design, data collection, data and statistical analysis, paper drafting, critical revision, and final approval of paper	has done study conception and design, data collection, data and statistical analysis, paper drafting, critical revision, and final approval of paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5073925	27766960	AMA	2	participated in manuscript preparation, drafting, critical review and revision	participated in manuscript preparation, drafting, critical review and revision	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5073925	27766960	EA	2	participated in manuscript preparation, drafting, critical review and revision	participated in manuscript preparation, drafting, critical review and revision	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5073925	27766960	GAD	2	participated in manuscript preparation, drafting, critical review and revision	participated in manuscript preparation, drafting, critical review and revision	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5073925	27766960	IAS	2	conducted literature search, prepared manuscript outline, and revision	conducted literature search, prepared manuscript outline, and revision	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5073925	27766960	IAT	2	participated in manuscript preparation, drafting, critical review and revision	participated in manuscript preparation, drafting, critical review and revision	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5073925	27766960	MA	2	participated in manuscript preparation, drafting, critical review and revision|participated in manuscript preparation, drafting, critical review and revision	participated in manuscript preparation, drafting, critical review and revision	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5073925	27766960	MA	2	participated in manuscript preparation, drafting, critical review and revision|participated in manuscript preparation, drafting, critical review and revision	participated in manuscript preparation, drafting, critical review and revision	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5073925	27766960	MAB	2	conducted literature search, prepared manuscript outline, and revision	conducted literature search, prepared manuscript outline, and revision	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5073925	27766960	MR	2	participated in manuscript preparation, drafting, critical review and revision	participated in manuscript preparation, drafting, critical review and revision	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5073925	27766960	MSJ	2	participated in manuscript preparation, drafting, critical review and revision	participated in manuscript preparation, drafting, critical review and revision	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5073925	27766960	OSB	2	participated in manuscript preparation, drafting, critical review and revision	participated in manuscript preparation, drafting, critical review and revision	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5073925	27766960	RFT	2	participated in manuscript preparation, drafting, critical review and revision	participated in manuscript preparation, drafting, critical review and revision	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5073925	27766960	SFA	2	participated in manuscript preparation, drafting, critical review and revision	participated in manuscript preparation, drafting, critical review and revision	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4399939	25880554	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399939	25880554	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399939	25880554	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399939	25880554	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399939	25880554	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399939	25880554	BH	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399939	25880554	BH	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4399939	25880554	DD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399939	25880554	DD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399939	25880554	DD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399939	25880554	DG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399939	25880554	DG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399939	25880554	DG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399939	25880554	DG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399939	25880554	DG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399939	25880554	DP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399939	25880554	DP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4399939	25880554	DP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4399939	25880554	DP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399939	25880554	MMD	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399939	25880554	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399939	25880554	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4399939	25880554	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4399939	25880554	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399939	25880554	RC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399939	25880554	RC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4399939	25880554	RC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4399939	25880554	RC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399939	25880554	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399939	25880554	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399939	25880554	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399939	25880554	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5461300	28638387	EC	2	planned and designed the research|interpreted the results and wrote the manuscript	planned and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5461300	28638387	EC	2	planned and designed the research|interpreted the results and wrote the manuscript	interpreted the results and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5461300	28638387	MB	2	performed qtl detection	performed qtl detection	Performed the experiments	Investigation	YES
5461300	28638387	Therefore Marco Bink	2	have no competing interests to declare	have no competing interests to declare	-	-	NO
5461300	28638387	all other authors	2	have no competing interests to declare	have no competing interests to declare	-	-	NO
5516188	28397412	D.N.	2	contributed substantially to the study design, interpretation of the results, and writing of the manuscript	contributed substantially to the study design, interpretation of the results, and writing of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5516188	28397412	H.M.	2	supported the data processing and writing of the manuscript	supported the data processing and writing of the manuscript	Analyzed the data|Wrote the paper	Data curation|Writing - Original Draft	YES
5516188	28397412	K.M.	2	supported the data processing and writing of the manuscript	supported the data processing and writing of the manuscript	Analyzed the data|Wrote the paper	Data curation|Writing - Original Draft	YES
5516188	28397412	L.S.	2	was involved in discussions of the analytical approach to this study and made comments on the results	was involved in discussions of the analytical approach to this study and made comments on the results	Analyzed the data	Formal analysis	YES
5516188	28397412	L.T.	2	contributed substantially to the study design, interpretation of the results, and writing of the manuscript	contributed substantially to the study design, interpretation of the results, and writing of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5516188	28397412	M.I.	2	planned the study, carried out the data extraction, processing and analysis, and drafted the manuscript	planned the study, carried out the data extraction, processing and analysis, and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Data curation|Formal analysis|Writing - Original Draft	YES
3835788	24256692	ATB	2	contributed to the study concept and design, analysis and interpretation of the data, in addition to drafting and critical revision of the manuscript for important intellectual content	contributed to the study concept and design, analysis and interpretation of the data, in addition to drafting and critical revision of the manuscript for important intellectual content	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
3835788	24256692	All authors	2	contributed to and approved the final manuscript	contributed to and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
3835788	24256692	IS	2	contributed to the acquisition of data, provided critical revision of the manuscript and obtained funding	contributed to the acquisition of data, provided critical revision of the manuscript and obtained funding	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Funding acquisition|Investigation|Resources|Writing - Review & Editing	YES
3835788	24256692	KS	2	contributed to the analysis and interpretation of the data and critical revision of the manuscript	contributed to the analysis and interpretation of the data and critical revision of the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
3835788	24256692	LL	2	provided critical revision of the manuscript and obtained funding	provided critical revision of the manuscript and obtained funding	Wrote the paper	Funding acquisition|Writing - Review & Editing	YES
3835788	24256692	MM	2	contributed to the analysis and interpretation of the data and critical revision of the manuscript	contributed to the analysis and interpretation of the data and critical revision of the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
3835788	24256692	MPF	2	contributed to the study concept and design, analysis and interpretation of the data, in addition to drafting and critical revision of the manuscript for important intellectual content	contributed to the study concept and design, analysis and interpretation of the data, in addition to drafting and critical revision of the manuscript for important intellectual content	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
3835788	24256692	PI	2	contributed to the analysis and interpretation of the data and critical revision of the manuscript	contributed to the analysis and interpretation of the data and critical revision of the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
3227871	22135716	JgS	2	carried out the data collection and analysis, and wrote the manuscript|developed the study design and revised the manuscript critically for important intellectual content	carried out the data collection and analysis, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3227871	22135716	JgS	2	carried out the data collection and analysis, and wrote the manuscript|developed the study design and revised the manuscript critically for important intellectual content	developed the study design and revised the manuscript critically for important intellectual content	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft|Writing - Review & Editing	YES
3227871	22135716	SM	2	developed the study design and revised the manuscript critically for important intellectual content	developed the study design and revised the manuscript critically for important intellectual content	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft|Writing - Review & Editing	YES
3227871	22135716	SS	2	carried out the interviews with the staff members and offered an alternative perspective during the analyzation and interpretation process	carried out the interviews with the staff members and offered an alternative perspective during the analyzation and interpretation process	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3227871	22135716	WS	2	developed the study design and revised the manuscript critically for important intellectual content	developed the study design and revised the manuscript critically for important intellectual content	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5073957	27766959	AR	2	coordination of the work and critical revision of the manuscript	coordination of the work and critical revision of the manuscript	Wrote the paper	Project administration|Writing - Review & Editing	YES
5073957	27766959	MA	2	contributed in manuscript drafting and editing	contributed in manuscript drafting and editing	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5073957	27766959	MHA	2	participated in manuscript drafting	participated in manuscript drafting	Wrote the paper	Writing - Original Draft	YES
5073957	27766959	NK	2	study conception, data analysis and manuscript drafting	study conception, data analysis and manuscript drafting	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
5073957	27766959	RA	2	involved in data analysis and manuscript editing	involved in data analysis and manuscript editing	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5073957	27766959	RBM	2	participated in data analysis	participated in data analysis	Analyzed the data	Formal analysis	YES
5073957	27766959	SB	2	contributed in data acquisition and analysis	contributed in data acquisition and analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
4399940	25880764	GZ	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399940	25880764	HH	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399940	25880764	HH	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399940	25880764	HH	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399940	25880764	LS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399940	25880764	SL	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399940	25880764	SL	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5573984	28370596	A.F.C.	2	performed the study	performed the study	Performed the experiments	Investigation	YES
5573984	28370596	A.M.	2	performed the study	performed the study	Performed the experiments	Investigation	YES
5573984	28370596	All authors	2	were involved in the conception or the design of the study, participated in the collection or generation of the data, contributed to the materials/analysis tools and were involved in the analyses and interpretation of the data|reviewed and commented on manuscript drafts and gave final approval for it to be submitted for publication	were involved in the conception or the design of the study, participated in the collection or generation of the data, contributed to the materials/analysis tools and were involved in the analyses and interpretation of the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Methodology|Resources	YES
5573984	28370596	All authors	2	were involved in the conception or the design of the study, participated in the collection or generation of the data, contributed to the materials/analysis tools and were involved in the analyses and interpretation of the data|reviewed and commented on manuscript drafts and gave final approval for it to be submitted for publication	reviewed and commented on manuscript drafts and gave final approval for it to be submitted for publication	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5573984	28370596	M.E.J.	2	performed the study	performed the study	Performed the experiments	Investigation	YES
5461335	28638399	AS	2	conceived the research|performed data analysis|wrote the manuscript	conceived the research	Conceived and designed the experiments	Conceptualization	YES
5461335	28638399	AS	2	conceived the research|performed data analysis|wrote the manuscript	performed data analysis	Analyzed the data	Formal analysis	YES
5461335	28638399	AS	2	conceived the research|performed data analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5461335	28638399	BW	2	conceived the research	conceived the research	Conceived and designed the experiments	Conceptualization	YES
5461335	28638399	MF	2	performed data analysis	performed data analysis	Analyzed the data	Formal analysis	YES
5461335	28638399	RS	2	conceived the research|wrote the manuscript	conceived the research	Conceived and designed the experiments	Conceptualization	YES
5461335	28638399	RS	2	conceived the research|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
1074340	15813990	JA	2	carried out all of the experiments	carried out all of the experiments	Performed the experiments	Investigation	YES
1074340	15813990	RA	2	was responsible for the overall experimental design and implementation of the project	was responsible for the overall experimental design and implementation of the project	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3838571	24267671	GW	2	designed the study, performed statistical analyses and wrote the first draft of the manuscript	designed the study, performed statistical analyses and wrote the first draft of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3838571	24267671	JE	2	contributed to the study design and commented on the manuscript	contributed to the study design and commented on the manuscript	Conceived and designed the experiments	Methodology	YES
3838571	24267671	KP	2	contributed to the study design and commented on the manuscript	contributed to the study design and commented on the manuscript	Conceived and designed the experiments	Methodology	YES
3838571	24267671	MD	2	contributed to the study design and commented on the manuscript	contributed to the study design and commented on the manuscript	Conceived and designed the experiments	Methodology	YES
3838571	24267671	ME	2	contributed to the study design and commented on the manuscript	contributed to the study design and commented on the manuscript	Conceived and designed the experiments	Methodology	YES
3838571	24267671	NDL	2	designed the study, performed statistical analyses and wrote the first draft of the manuscript	designed the study, performed statistical analyses and wrote the first draft of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3838571	24267671	OK	2	contributed to the study design and commented on the manuscript	contributed to the study design and commented on the manuscript	Conceived and designed the experiments	Methodology	YES
3838571	24267671	SM	2	contributed to the study design and commented on the manuscript|was responsible for data collection from 2008 to 2011	contributed to the study design and commented on the manuscript	Conceived and designed the experiments	Methodology	YES
3838571	24267671	SM	2	contributed to the study design and commented on the manuscript|was responsible for data collection from 2008 to 2011	was responsible for data collection from 2008 to 2011	Performed the experiments	Investigation	YES
3838571	24267671	TL	2	contributed to the study design and commented on the manuscript	contributed to the study design and commented on the manuscript	Conceived and designed the experiments	Methodology	YES
5073958	27766962	AJF	2	were responsible for sample collection and of clinical databases	were responsible for sample collection and of clinical databases	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5073958	27766962	AMA	2	were involved in expression arrays and data interpretation	were involved in expression arrays and data interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5073958	27766962	AS	2	were responsible for sample collection and of clinical databases	were responsible for sample collection and of clinical databases	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5073958	27766962	EIA	2	were involved in expression arrays and data interpretation	were involved in expression arrays and data interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5073958	27766962	FB	2	made substantial contributions to design the study|drafted the manuscript	made substantial contributions to design the study	Conceived and designed the experiments	Methodology	YES
5073958	27766962	FB	2	made substantial contributions to design the study|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5073958	27766962	MHA	2	were involved in expression arrays and data interpretation	were involved in expression arrays and data interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5073958	27766962	MIN	2	made substantial contributions to design the study|drafted the manuscript	made substantial contributions to design the study	Conceived and designed the experiments	Methodology	YES
5073958	27766962	MIN	2	made substantial contributions to design the study|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5073958	27766962	MY	2	were involved in expression arrays and data interpretation	were involved in expression arrays and data interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5073958	27766962	SA	2	were involved in expression arrays and data interpretation	were involved in expression arrays and data interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4399941	25880806	ABYH	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399941	25880806	AF	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399941	25880806	BAC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399941	25880806	CH	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399941	25880806	CH	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399941	25880806	CH	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399941	25880806	DH	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399941	25880806	DW	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399941	25880806	FFL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399941	25880806	FFL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399941	25880806	JPB	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4399941	25880806	MM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399941	25880806	MP	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4399941	25880806	PCB	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399941	25880806	PW	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4399941	25880806	RPH	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399941	25880806	RY	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4399941	25880806	SY	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4399942	25881015	ATPP	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399942	25881015	ATPP	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399942	25881015	ATPP	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399942	25881015	JJE	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399942	25881015	JJE	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399942	25881015	JJE	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399942	25881015	JJE	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399942	25881015	JRC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399942	25881015	JRC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399942	25881015	JRC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399942	25881015	LS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399942	25881015	LS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399942	25881015	LS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399942	25881015	LS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399942	25881015	MN	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399942	25881015	MN	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399942	25881015	MN	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399942	25881015	VS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399942	25881015	VS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399942	25881015	VS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399942	25881015	ZML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399942	25881015	ZML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399942	25881015	ZML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399942	25881015	ZML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3841298	24280372	GR	2	was the principal investigator at the mira durban clinical research sites|interpreted and drafted the manuscript	was the principal investigator at the mira durban clinical research sites	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
3841298	24280372	GR	2	was the principal investigator at the mira durban clinical research sites|interpreted and drafted the manuscript	interpreted and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3841298	24280372	HW	2	formulated the research question and performed the statistical analysis|interpreted and drafted the manuscript	formulated the research question and performed the statistical analysis	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
3841298	24280372	HW	2	formulated the research question and performed the statistical analysis|interpreted and drafted the manuscript	interpreted and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5073984	27766953	AMA	2	provided clinical specimens	provided clinical specimens	Performed the experiments	Investigation	YES
5073984	27766953	BH	2	conducted experiments, wrote manuscript	conducted experiments, wrote manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5073984	27766953	FSA	2	provided clinical specimens	provided clinical specimens	Performed the experiments	Investigation	YES
5073984	27766953	HH	2	helped with screening of candidate	helped with screening of candidate	Performed the experiments	Investigation	YES
5073984	27766953	JWS	2	coordinated research, edited paper	coordinated research, edited paper	Wrote the paper	Project administration|Writing - Review & Editing	YES
5073984	27766953	MSM	2	provided clinical specimens	provided clinical specimens	Performed the experiments	Investigation	YES
5073984	27766953	NZ	2	analyzed telomere length	analyzed telomere length	Analyzed the data	Formal analysis	YES
5073984	27766953	T-PL	2	conducted experiments telomere length	conducted experiments telomere length	Performed the experiments	Investigation	YES
5073984	27766953	WEW	2	conceived some ideas behind the experiments	conceived some ideas behind the experiments	Conceived and designed the experiments	Conceptualization	YES
5073984	27766953	WK	2	conducted experiments	conducted experiments	Performed the experiments	Investigation	YES
5461349	28638398	AR	2	edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5461349	28638398	All co-authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5461349	28638398	DK	2	conceived theme of the study|drafted the manuscript	conceived theme of the study	Conceived and designed the experiments	Conceptualization	YES
5461349	28638398	DK	2	conceived theme of the study|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5461349	28638398	DS	2	did the computational analysis of generated data	did the computational analysis of generated data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5461349	28638398	KA	2	collected sample	collected sample	Performed the experiments	Investigation	YES
5461349	28638398	KS	2	collected sample|drafted the manuscript	collected sample	Performed the experiments	Investigation	YES
5461349	28638398	KS	2	collected sample|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5461349	28638398	MI	2	did the computational analysis of generated data|drafted the manuscript	did the computational analysis of generated data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5461349	28638398	MI	2	did the computational analysis of generated data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5461349	28638398	NS	2	edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5461349	28638398	PG	2	collected sample	collected sample	Performed the experiments	Investigation	YES
5461349	28638398	PS	2	collected sample	collected sample	Performed the experiments	Investigation	YES
5461349	28638398	RJ	2	did the computational analysis of generated data	did the computational analysis of generated data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5461349	28638398	RV	2	edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5461349	28638398	SC	2	conceived theme of the study|edited the manuscript	conceived theme of the study	Conceived and designed the experiments	Conceptualization	YES
5461349	28638398	SC	2	conceived theme of the study|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5461349	28638398	SJ	2	did the computational analysis of generated data|drafted the manuscript	did the computational analysis of generated data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5461349	28638398	SJ	2	did the computational analysis of generated data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
1074342	15813986	AB	2	carried out most of the experiments	carried out most of the experiments	Performed the experiments	Investigation	YES
1074342	15813986	JR	2	were responsible for vector design and preparation	were responsible for vector design and preparation	Conceived and designed the experiments	-	YES
1074342	15813986	LR	2	assisted in scid-hu mice generation, cd34 cell reconstitutions into mice	assisted in scid-hu mice generation, cd34 cell reconstitutions into mice	Performed the experiments	Investigation	YES
1074342	15813986	M Li	2	were responsible for vector design and preparation	were responsible for vector design and preparation	Conceived and designed the experiments	-	YES
1074342	15813986	PCR	2	facs analysis	facs analysis	-	-	NO
1074342	15813986	RA	2	was responsible for the overall experimental design and implementation of the project	was responsible for the overall experimental design and implementation of the project	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3361162	22654588	G. Nocentini	2	equally contributed to the paper	equally contributed to the paper	-	-	NO
3361162	22654588	S. Ronchetti	2	equally contributed to the paper	equally contributed to the paper	-	-	NO
4399946	25880228	BV	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399946	25880228	BV	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399946	25880228	DH	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399946	25880228	DH	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399946	25880228	JF	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399946	25880228	JF	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399946	25880228	MAT	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399946	25880228	STRR	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399946	25880228	STRR	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399946	25880228	STRR	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3843110	24286556	MBP	2	both contributed to the conception, design, acquisition of data, analysis and interpretation of data and have been involved in drafting the manuscript	both contributed to the conception, design, acquisition of data, analysis and interpretation of data and have been involved in drafting the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Resources|Writing - Original Draft	YES
3843110	24286556	MOP	2	both contributed to the conception, design, acquisition of data, analysis and interpretation of data and have been involved in drafting the manuscript	both contributed to the conception, design, acquisition of data, analysis and interpretation of data and have been involved in drafting the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Resources|Writing - Original Draft	YES
1087826	15826302	A.J.M.	2	performed the laboratory work presented in this paper	performed the laboratory work presented in this paper	Performed the experiments	Investigation	YES
1087826	15826302	D.M.	2	was the statistician for a5014 and 5036	was the statistician for a5014 and 5036	Analyzed the data	Formal analysis	YES
1087826	15826302	D.R.K.	2	was the protocol virologist for a5014	was the protocol virologist for a5014	Conceived and designed the experiments	Methodology	YES
1087826	15826302	E.J.A.	2	supervised the laboratory work	supervised the laboratory work	Performed the experiments	Investigation|Supervision	YES
1087826	15826302	H.B.	2	performed the laboratory work presented in this paper	performed the laboratory work presented in this paper	Performed the experiments	Investigation	YES
1087826	15826302	PIs	2	of the parent study a5014	of the parent study a5014	-	-	NO
5073988	27766958	AB	2	contributed to review of the data and preparation of the manuscript	contributed to review of the data and preparation of the manuscript	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Original Draft|Writing - Review & Editing	YES
5073988	27766958	ADA	2	was the lead scientist who processed the bones, typed samples, analyzed the data, and prepared the manuscript	was the lead scientist who processed the bones, typed samples, analyzed the data, and prepared the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Formal analysis|Investigation|Writing - Original Draft	YES
5073988	27766958	BB	2	designed the study, performed data analyses, and contributed to manuscript preparation	designed the study, performed data analyses, and contributed to manuscript preparation	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5073988	27766958	G-K	2	facilitated acquisition of the samples and contributed to the design of the study	facilitated acquisition of the samples and contributed to the design of the study	Conceived and designed the experiments	Methodology	YES
5073988	27766958	JDC	2	generated sequencing data	generated sequencing data	Performed the experiments	Investigation	YES
5073988	27766958	JLK	2	performed data analyses	performed data analyses	Analyzed the data	Formal analysis	YES
5073988	27766958	MA	2	contributed to review of the data and preparation of the manuscript	contributed to review of the data and preparation of the manuscript	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Original Draft|Writing - Review & Editing	YES
5073988	27766958	MA-E	2	contributed to review of the data and preparation of the manuscript	contributed to review of the data and preparation of the manuscript	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Original Draft|Writing - Review & Editing	YES
5073988	27766958	MA-Q	2	contributed to review of the data and preparation of the manuscript	contributed to review of the data and preparation of the manuscript	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Original Draft|Writing - Review & Editing	YES
5073988	27766958	MK	2	generated sequencing data	generated sequencing data	Performed the experiments	Investigation	YES
5461362	28638393	DP	2	acquired and analyzed the data for which they were responsible, are accountable for its accuracy, and reviewed the manuscript for accuracy	acquired and analyzed the data for which they were responsible, are accountable for its accuracy, and reviewed the manuscript for accuracy	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
5461362	28638393	EG	2	was responsible for conceiving the research project, results analysis and interpretation, drafting, revising and approving the manuscript, and is accountable for the data reported inside	was responsible for conceiving the research project, results analysis and interpretation, drafting, revising and approving the manuscript, and is accountable for the data reported inside	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5461362	28638393	HE	2	was the lead designer of the experiments, and an integral part of result analysis and interpretation, drafting, revising and approving the manuscript, and is accountable for the accuracy of the reported experimental data	was the lead designer of the experiments, and an integral part of result analysis and interpretation, drafting, revising and approving the manuscript, and is accountable for the accuracy of the reported experimental data	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5461362	28638393	HZ	2	acquired and analyzed the data for which they were responsible, are accountable for its accuracy, and reviewed the manuscript for accuracy	acquired and analyzed the data for which they were responsible, are accountable for its accuracy, and reviewed the manuscript for accuracy	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
5461362	28638393	LT	2	was responsible for performing the physical and chemical characterization of the biochars|acquired and analyzed the data for which they were responsible, are accountable for its accuracy, and reviewed the manuscript for accuracy	was responsible for performing the physical and chemical characterization of the biochars	Performed the experiments	Investigation	YES
5461362	28638393	LT	2	was responsible for performing the physical and chemical characterization of the biochars|acquired and analyzed the data for which they were responsible, are accountable for its accuracy, and reviewed the manuscript for accuracy	acquired and analyzed the data for which they were responsible, are accountable for its accuracy, and reviewed the manuscript for accuracy	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
4399949	25880082	DB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399949	25880082	DB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399949	25880082	DB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399949	25880082	GMB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399949	25880082	GMB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399949	25880082	GMB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399949	25880082	GMB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399949	25880082	MZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399949	25880082	MZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399949	25880082	MZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399949	25880082	MZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399949	25880082	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399949	25880082	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399949	25880082	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399949	25880082	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399949	25880082	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3852123	24321112	All authors	2	were involved in study implementation|provided insight into key themes and interpretations, and all authors read and approved the final article	were involved in study implementation	Performed the experiments	Investigation	YES
3852123	24321112	All authors	2	were involved in study implementation|provided insight into key themes and interpretations, and all authors read and approved the final article	provided insight into key themes and interpretations, and all authors read and approved the final article	Analyzed the data	Formal analysis	YES
3852123	24321112	BS	2	assisted with participant recruitment and community sensitization	assisted with participant recruitment and community sensitization	Performed the experiments	Investigation	YES
3852123	24321112	CEK	2	conceptualized and designed the study|drafted the article	conceptualized and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3852123	24321112	CEK	2	conceptualized and designed the study|drafted the article	drafted the article	Wrote the paper	Writing - Original Draft	YES
3852123	24321112	DA	2	assisted with coding transcripts	assisted with coding transcripts	-	-	NO
3852123	24321112	DK	2	conceptualized and designed the study	conceptualized and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3852123	24321112	PD	2	assisted with participant recruitment and community sensitization|conducted interviews	assisted with participant recruitment and community sensitization	Performed the experiments	Investigation	YES
3852123	24321112	PD	2	assisted with participant recruitment and community sensitization|conducted interviews	conducted interviews	Performed the experiments	Investigation	YES
3852123	24321112	RF-M	2	conducted interviews|assisted with coding transcripts	conducted interviews	Performed the experiments	Investigation	YES
3852123	24321112	RF-M	2	conducted interviews|assisted with coding transcripts	assisted with coding transcripts	-	-	NO
3852123	24321112	SDB	2	conceptualized and designed the study	conceptualized and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3852123	24321112	VAF	2	assisted with coding transcripts	assisted with coding transcripts	-	-	NO
3852123	24321112	ZM	2	conceptualized and designed the study	conceptualized and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5461368	28638400	All authors	2	read and approved the manuscript	read and approved the manuscript	-	-	NO
5461368	28638400	DL	2	conceived and designed research|analyzed data and prepared the manuscript	conceived and designed research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5461368	28638400	DL	2	conceived and designed research|analyzed data and prepared the manuscript	analyzed data and prepared the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5461368	28638400	HL	2	provided plant materials	provided plant materials	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5461368	28638400	HW	2	conceived and designed research|conduced the laboratory works	conceived and designed research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5461368	28638400	HW	2	conceived and designed research|conduced the laboratory works	conduced the laboratory works	Performed the experiments	Investigation	YES
5461368	28638400	JH	2	conceived and designed research|analyzed data and prepared the manuscript	conceived and designed research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5461368	28638400	JH	2	conceived and designed research|analyzed data and prepared the manuscript	analyzed data and prepared the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5461368	28638400	JZ	2	conceived and designed research|conduced the laboratory works|analyzed data and prepared the manuscript	conceived and designed research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5461368	28638400	JZ	2	conceived and designed research|conduced the laboratory works|analyzed data and prepared the manuscript	conduced the laboratory works	Performed the experiments	Investigation	YES
5461368	28638400	JZ	2	conceived and designed research|conduced the laboratory works|analyzed data and prepared the manuscript	analyzed data and prepared the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4399977	25881129	HMB	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399977	25881129	JMV	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399977	25881129	JMV	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399977	25881129	JPS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399977	25881129	NT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399977	25881129	NT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399977	25881129	NT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399977	25881129	NT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3852125	24321118	AC	2	all contributed to the preparation of the first draft	all contributed to the preparation of the first draft	Wrote the paper	Writing - Original Draft	YES
3852125	24321118	DC	2	all contributed to the preparation of the first draft	all contributed to the preparation of the first draft	Wrote the paper	Writing - Original Draft	YES
3852125	24321118	LK	2	all contributed to the preparation of the first draft	all contributed to the preparation of the first draft	Wrote the paper	Writing - Original Draft	YES
3852125	24321118	RCW	2	all contributed to the preparation of the first draft	all contributed to the preparation of the first draft	Wrote the paper	Writing - Original Draft	YES
1131887	15877818	DS	1	Data searching and abstraction|Data analysis|Manuscript drafts|Approval of final manuscript	Data searching and abstraction	-	-	NO
1131887	15877818	DS	1	Data searching and abstraction|Data analysis|Manuscript drafts|Approval of final manuscript	Data analysis	Analyzed the data	Formal analysis	YES
1131887	15877818	DS	1	Data searching and abstraction|Data analysis|Manuscript drafts|Approval of final manuscript	Manuscript drafts	Wrote the paper	Writing - Original Draft	YES
1131887	15877818	DS	1	Data searching and abstraction|Data analysis|Manuscript drafts|Approval of final manuscript	Approval of final manuscript	Wrote the paper	Writing - Review & Editing	YES
1131887	15877818	EM	1	Concept, protocol|Data searching and abstraction|Data analysis|Manuscript drafts|Approval of final manuscript	Concept, protocol	Conceived and designed the experiments	Conceptualization|Methodology	YES
1131887	15877818	EM	1	Concept, protocol|Data searching and abstraction|Data analysis|Manuscript drafts|Approval of final manuscript	Data searching and abstraction	-	-	NO
1131887	15877818	EM	1	Concept, protocol|Data searching and abstraction|Data analysis|Manuscript drafts|Approval of final manuscript	Data analysis	Analyzed the data	Formal analysis	YES
1131887	15877818	EM	1	Concept, protocol|Data searching and abstraction|Data analysis|Manuscript drafts|Approval of final manuscript	Manuscript drafts	Wrote the paper	Writing - Original Draft	YES
1131887	15877818	EM	1	Concept, protocol|Data searching and abstraction|Data analysis|Manuscript drafts|Approval of final manuscript	Approval of final manuscript	Wrote the paper	Writing - Review & Editing	YES
1131887	15877818	GG	1	Concept, protocol|Data analysis|Manuscript drafts|Approval of final manuscript	Concept, protocol	Conceived and designed the experiments	Conceptualization|Methodology	YES
1131887	15877818	GG	1	Concept, protocol|Data analysis|Manuscript drafts|Approval of final manuscript	Data analysis	Analyzed the data	Formal analysis	YES
1131887	15877818	GG	1	Concept, protocol|Data analysis|Manuscript drafts|Approval of final manuscript	Manuscript drafts	Wrote the paper	Writing - Original Draft	YES
1131887	15877818	GG	1	Concept, protocol|Data analysis|Manuscript drafts|Approval of final manuscript	Approval of final manuscript	Wrote the paper	Writing - Review & Editing	YES
1131887	15877818	PW	1	Concept, protocol|Data searching and abstraction|Data analysis|Manuscript drafts|Approval of final manuscript	Concept, protocol	Conceived and designed the experiments	Conceptualization|Methodology	YES
1131887	15877818	PW	1	Concept, protocol|Data searching and abstraction|Data analysis|Manuscript drafts|Approval of final manuscript	Data searching and abstraction	-	-	NO
1131887	15877818	PW	1	Concept, protocol|Data searching and abstraction|Data analysis|Manuscript drafts|Approval of final manuscript	Data analysis	Analyzed the data	Formal analysis	YES
1131887	15877818	PW	1	Concept, protocol|Data searching and abstraction|Data analysis|Manuscript drafts|Approval of final manuscript	Manuscript drafts	Wrote the paper	Writing - Original Draft	YES
1131887	15877818	PW	1	Concept, protocol|Data searching and abstraction|Data analysis|Manuscript drafts|Approval of final manuscript	Approval of final manuscript	Wrote the paper	Writing - Review & Editing	YES
5075209	27769169	AKM	2	analyzed ngs data	analyzed ngs data	Analyzed the data	Formal analysis	YES
5075209	27769169	BG	2	performed ngs experiments	performed ngs experiments	Performed the experiments	Investigation	YES
5075209	27769169	JHW	2	designed the study and prepared the manuscript|performed experiments to collect dna samples	designed the study and prepared the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5075209	27769169	JHW	2	designed the study and prepared the manuscript|performed experiments to collect dna samples	performed experiments to collect dna samples	Performed the experiments	Investigation	YES
5075209	27769169	KD	2	performed ngs experiments	performed ngs experiments	Performed the experiments	Investigation	YES
5075209	27769169	KG	2	analyzed ngs data	analyzed ngs data	Analyzed the data	Formal analysis	YES
5075209	27769169	KJ	2	analyzed ngs data	analyzed ngs data	Analyzed the data	Formal analysis	YES
5075209	27769169	SML	2	analyzed ngs data	analyzed ngs data	Analyzed the data	Formal analysis	YES
5075209	27769169	SSV	2	performed experiments to collect dna samples	performed experiments to collect dna samples	Performed the experiments	Investigation	YES
5075209	27769169	TK	2	performed experiments to collect dna samples	performed experiments to collect dna samples	Performed the experiments	Investigation	YES
5075209	27769169	ZC	2	designed the study and prepared the manuscript|performed experiments to collect dna samples	designed the study and prepared the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5075209	27769169	ZC	2	designed the study and prepared the manuscript|performed experiments to collect dna samples	performed experiments to collect dna samples	Performed the experiments	Investigation	YES
4399978	25880496	HZ	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4399978	25880496	HZ	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399978	25880496	JS	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399978	25880496	JS	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4399978	25880496	LL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Clinical data collection	Performed the experiments	Performed the experiments	Investigation	YES
4399978	25880496	LL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Clinical data collection	Analyzed the data	Analyzed the data	Formal analysis	YES
4399978	25880496	LL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Clinical data collection	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399978	25880496	LL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Clinical data collection	Clinical data collection	Performed the experiments	Investigation	YES
4399978	25880496	LQ	PLoS5	Contributed reagents/materials/analysis tools|Clinical data collection	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399978	25880496	LQ	PLoS5	Contributed reagents/materials/analysis tools|Clinical data collection	Clinical data collection	Performed the experiments	Investigation	YES
4399978	25880496	RY	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4399978	25880496	SJ	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399978	25880496	SJ	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399978	25880496	XL	PLoS5	Performed the experiments|Clinical data collection	Performed the experiments	Performed the experiments	Investigation	YES
4399978	25880496	XL	PLoS5	Performed the experiments|Clinical data collection	Clinical data collection	Performed the experiments	Investigation	YES
5461369	28638401	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5461369	28638401	FF	2	designed the research|performed molecular and field experiments|analyzed data and wrote the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
5461369	28638401	FF	2	designed the research|performed molecular and field experiments|analyzed data and wrote the manuscript	performed molecular and field experiments	Performed the experiments	Investigation	YES
5461369	28638401	FF	2	designed the research|performed molecular and field experiments|analyzed data and wrote the manuscript	analyzed data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5461369	28638401	GH	2	designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
5461369	28638401	HS	2	performed molecular and field experiments	performed molecular and field experiments	Performed the experiments	Investigation	YES
5461369	28638401	JW	2	performed molecular and field experiments	performed molecular and field experiments	Performed the experiments	Investigation	YES
5461369	28638401	NL	2	performed molecular and field experiments	performed molecular and field experiments	Performed the experiments	Investigation	YES
5461369	28638401	SL	2	designed the research|analyzed data and wrote the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
5461369	28638401	SL	2	designed the research|analyzed data and wrote the manuscript	analyzed data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5461369	28638401	XL	2	performed molecular and field experiments	performed molecular and field experiments	Performed the experiments	Investigation	YES
5461369	28638401	YC	2	performed molecular and field experiments	performed molecular and field experiments	Performed the experiments	Investigation	YES
5461369	28638401	YZ	2	designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
1156864	15907202	HIV	2	testing for the vcct counsellors, and contributed to acquisition of data from the laboratory	testing for the vcct counsellors, and contributed to acquisition of data from the laboratory	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
1156864	15907202	K Kakimoto	2	carried out data analysis and drafted this manuscript	carried out data analysis and drafted this manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
1156864	15907202	K. Kakimoto	2	conceived of the design of this study with intellectual contribution	conceived of the design of this study with intellectual contribution	Conceived and designed the experiments	Conceptualization|Methodology	YES
1156864	15907202	K. Kanal	2	carried out data analysis and drafted this manuscript	carried out data analysis and drafted this manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
1156864	15907202	PMTCT	2	in this study	in this study	-	-	NO
3852126	24321109	ADS	PLoS52	conceived and designed the focus group discussions	conceived and designed the focus group discussions	Conceived and designed the experiments	Conceptualization	YES
3852126	24321109	AO	PLoS52	conceived and designed the focus group discussions	conceived and designed the focus group discussions	Conceived and designed the experiments	Conceptualization	YES
3852126	24321109	DO	PLoS52	conceived and designed the focus group discussions|analyzed the data|wrote this article	conceived and designed the focus group discussions	Conceived and designed the experiments	Conceptualization	YES
3852126	24321109	DO	PLoS52	conceived and designed the focus group discussions|analyzed the data|wrote this article	analyzed the data	Analyzed the data	Formal analysis	YES
3852126	24321109	DO	PLoS52	conceived and designed the focus group discussions|analyzed the data|wrote this article	wrote this article	Wrote the paper	Writing - Original Draft	YES
3852126	24321109	EG	PLoS52	conceived and designed the focus group discussions|conducted the focus group discussions	conceived and designed the focus group discussions	Conceived and designed the experiments	Conceptualization	YES
3852126	24321109	EG	PLoS52	conceived and designed the focus group discussions|conducted the focus group discussions	conducted the focus group discussions	Performed the experiments	Investigation	YES
3852126	24321109	EJS	PLoS52	conceived and designed the focus group discussions	conceived and designed the focus group discussions	Conceived and designed the experiments	Conceptualization	YES
3852126	24321109	EMvdE	PLoS52	conceived and designed the focus group discussions|conducted the focus group discussions|analyzed the data|wrote this article	conceived and designed the focus group discussions	Conceived and designed the experiments	Conceptualization	YES
3852126	24321109	EMvdE	PLoS52	conceived and designed the focus group discussions|conducted the focus group discussions|analyzed the data|wrote this article	conducted the focus group discussions	Performed the experiments	Investigation	YES
3852126	24321109	EMvdE	PLoS52	conceived and designed the focus group discussions|conducted the focus group discussions|analyzed the data|wrote this article	analyzed the data	Analyzed the data	Formal analysis	YES
3852126	24321109	EMvdE	PLoS52	conceived and designed the focus group discussions|conducted the focus group discussions|analyzed the data|wrote this article	wrote this article	Wrote the paper	Writing - Original Draft	YES
3852126	24321109	JK	PLoS52	conceived and designed the focus group discussions|conducted the focus group discussions	conceived and designed the focus group discussions	Conceived and designed the experiments	Conceptualization	YES
3852126	24321109	JK	PLoS52	conceived and designed the focus group discussions|conducted the focus group discussions	conducted the focus group discussions	Performed the experiments	Investigation	YES
3852126	24321109	MM	PLoS52	analyzed the data|wrote this article	analyzed the data	Analyzed the data	Formal analysis	YES
3852126	24321109	MM	PLoS52	analyzed the data|wrote this article	wrote this article	Wrote the paper	Writing - Original Draft	YES
3852126	24321109	SMG	PLoS52	conceived and designed the focus group discussions	conceived and designed the focus group discussions	Conceived and designed the experiments	Conceptualization	YES
3852126	24321109	SS	PLoS52	analyzed the data|wrote this article	analyzed the data	Analyzed the data	Formal analysis	YES
3852126	24321109	SS	PLoS52	analyzed the data|wrote this article	wrote this article	Wrote the paper	Writing - Original Draft	YES
3852126	24321109	ZD	PLoS52	conceived and designed the focus group discussions	conceived and designed the focus group discussions	Conceived and designed the experiments	Conceptualization	YES
1198215	16109178	LH	2	contributed to the conception of the study, data interpretation, and writing of the paper	contributed to the conception of the study, data interpretation, and writing of the paper	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Resources|Writing - Original Draft	YES
1198215	16109178	LR	2	contributed to the conception of the study, data interpretation, and writing of the paper	contributed to the conception of the study, data interpretation, and writing of the paper	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Resources|Writing - Original Draft	YES
1198215	16109178	MG	2	contributed to the conception of the study, data interpretation, and writing of the paper	contributed to the conception of the study, data interpretation, and writing of the paper	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Resources|Writing - Original Draft	YES
1198215	16109178	RWP	2	contributed to the conception of the study, data interpretation, and writing of the paper	contributed to the conception of the study, data interpretation, and writing of the paper	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Resources|Writing - Original Draft	YES
1198215	16109178	SGD	2	contributed to the establishment of the clinical study and writing the paper	contributed to the establishment of the clinical study and writing the paper	Wrote the paper	Writing - Original Draft	YES
4399980	25881304	DZ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399980	25881304	GZN	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4399980	25881304	LC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399980	25881304	LXC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399980	25881304	LXC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399980	25881304	LXC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399980	25881304	QLW	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399980	25881304	SQF	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399980	25881304	TSZ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399980	25881304	YLL	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4399980	25881304	ZRZ	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
3852127	24321114	All authors	2	collaborated in writing sections of the manuscript, gave critical input and assisted with data analysis	collaborated in writing sections of the manuscript, gave critical input and assisted with data analysis	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3852127	24321114	IM	2	led the implementation	led the implementation	Performed the experiments	Investigation	YES
3852127	24321114	JE	2	led the implementation	led the implementation	Performed the experiments	Investigation	YES
3852127	24321114	JNP	2	developed the analytic plan|performed the statistical analysis and wrote the first draft of the article	developed the analytic plan	-	-	NO
3852127	24321114	JNP	2	developed the analytic plan|performed the statistical analysis and wrote the first draft of the article	performed the statistical analysis and wrote the first draft of the article	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3852127	24321114	LM	2	led the implementation	led the implementation	Performed the experiments	Investigation	YES
3852127	24321114	ML	2	supervised sample collection and immunoassays	supervised sample collection and immunoassays	Performed the experiments	Investigation|Supervision	YES
3852127	24321114	NN	2	led the implementation	led the implementation	Performed the experiments	Investigation	YES
3852127	24321114	SB	2	developed the analytic plan	developed the analytic plan	-	-	NO
3852127	24321114	SK	2	led the implementation	led the implementation	Performed the experiments	Investigation	YES
3852127	24321114	UT	2	supervised sample collection and immunoassays	supervised sample collection and immunoassays	Performed the experiments	Investigation|Supervision	YES
3852127	24321114	YRY	2	led the implementation	led the implementation	Performed the experiments	Investigation	YES
5075214	27769171	BDW	PLoS52	participated in experiment materials preparation|participated in rna extraction	participated in experiment materials preparation	Performed the experiments	Investigation	YES
5075214	27769171	BDW	PLoS52	participated in experiment materials preparation|participated in rna extraction	participated in rna extraction	Performed the experiments	Investigation	YES
5075214	27769171	CYH	PLoS52	participated in experiment materials preparation|participated in rna extraction	participated in experiment materials preparation	Performed the experiments	Investigation	YES
5075214	27769171	CYH	PLoS52	participated in experiment materials preparation|participated in rna extraction	participated in rna extraction	Performed the experiments	Investigation	YES
5075214	27769171	HSW	PLoS52	conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5075214	27769171	LHT	PLoS52	participated in experiment materials preparation	participated in experiment materials preparation	Performed the experiments	Investigation	YES
5075214	27769171	LSH	PLoS52	participated in experiment materials preparation|performed qrt pcr	participated in experiment materials preparation	Performed the experiments	Investigation	YES
5075214	27769171	LSH	PLoS52	participated in experiment materials preparation|performed qrt pcr	performed qrt pcr	Performed the experiments	Investigation	YES
5075214	27769171	RF	PLoS52	participated in experiment materials preparation|participated in rna extraction|wrote the paper	participated in experiment materials preparation	Performed the experiments	Investigation	YES
5075214	27769171	RF	PLoS52	participated in experiment materials preparation|participated in rna extraction|wrote the paper	participated in rna extraction	Performed the experiments	Investigation	YES
5075214	27769171	RF	PLoS52	participated in experiment materials preparation|participated in rna extraction|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5075214	27769171	ZQX	PLoS52	participated in experiment materials preparation	participated in experiment materials preparation	Performed the experiments	Investigation	YES
6156089	30270985	A.M.	2	revised the manuscript and supervised the project	revised the manuscript and supervised the project	Wrote the paper	Supervision|Writing - Review & Editing	YES
6156089	30270985	K.Y.X.	2	designed the synthesis method and performed the synthesis and characterization|wrote the first version of the manuscript, and all authors discussed the results and contributed to the final version of the manuscript	designed the synthesis method and performed the synthesis and characterization	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6156089	30270985	K.Y.X.	2	designed the synthesis method and performed the synthesis and characterization|wrote the first version of the manuscript, and all authors discussed the results and contributed to the final version of the manuscript	wrote the first version of the manuscript, and all authors discussed the results and contributed to the final version of the manuscript	Wrote the paper	Writing - Original Draft	YES
4399981	25880730	ARL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399981	25880730	ARL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399981	25880730	ARL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399981	25880730	ARM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399981	25880730	ARM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399981	25880730	ARM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399981	25880730	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399981	25880730	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399981	25880730	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399981	25880730	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399981	25880730	FSM	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399981	25880730	FSM	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399981	25880730	HDLF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399981	25880730	HDLF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399981	25880730	HDLF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399981	25880730	HDLF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399981	25880730	MM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399981	25880730	MM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399981	25880730	MM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399981	25880730	MM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399981	25880730	MSN	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399981	25880730	MSN	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399981	25880730	MSN	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399981	25880730	RGA	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399981	25880730	RGA	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399981	25880730	SL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399981	25880730	SL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399981	25880730	SL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399981	25880730	SL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1215470	16156891	Barbara Schnierle	2	oversaw the conduction of the experiments and the interpretation of the results	oversaw the conduction of the experiments and the interpretation of the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Supervision	YES
5461430	28638392	AC	2	integration of the experimental setup for multi-view imaging of plants, imagery data acquisition and processing, and drafting of the manuscript	integration of the experimental setup for multi-view imaging of plants, imagery data acquisition and processing, and drafting of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Investigation|Visualization|Writing - Original Draft	YES
5461430	28638392	AF	2	experimental design and coordination of the work, interpretation of data, drafting and critical revision of the manuscript	experimental design and coordination of the work, interpretation of data, drafting and critical revision of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Project administration|Writing - Original Draft|Writing - Review & Editing	YES
5461430	28638392	AS	2	carried out the ethylene production study and analysis of the data, and participated in the experimental design, critically reading the manuscript drafts	carried out the ethylene production study and analysis of the data, and participated in the experimental design, critically reading the manuscript drafts	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5461430	28638392	EF	2	integration of the experimental setup for multi-view imaging of plants, imagery data acquisition and processing, and drafting of the manuscript	integration of the experimental setup for multi-view imaging of plants, imagery data acquisition and processing, and drafting of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Investigation|Visualization|Writing - Original Draft	YES
5461430	28638392	GC	2	elaboration and critical interpretation of data, drafting of the manuscript	elaboration and critical interpretation of data, drafting of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5461430	28638392	IM	2	carried out the ethylene production study and analysis of the data, and participated in the experimental design, critically reading the manuscript drafts	carried out the ethylene production study and analysis of the data, and participated in the experimental design, critically reading the manuscript drafts	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5461430	28638392	NN	2	substantial contribution to the biochemical work, interpretation of data, drafting and critical revision of the manuscript	substantial contribution to the biochemical work, interpretation of data, drafting and critical revision of the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5461430	28638392	RB	2	substantial contribution to the experimental work, interpretation of data, and drafting of the manuscript	substantial contribution to the experimental work, interpretation of data, and drafting of the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft	YES
5461430	28638392	RO	2	integration of the experimental setup for multi-view imaging of plants, imagery data acquisition and processing, and drafting of the manuscript	integration of the experimental setup for multi-view imaging of plants, imagery data acquisition and processing, and drafting of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Investigation|Visualization|Writing - Original Draft	YES
5461430	28638392	SF	2	designed and carried out the experiments on the coated plastic films	designed and carried out the experiments on the coated plastic films	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5461430	28638392	SM	2	substantial contribution to the biochemical work, interpretation of data, drafting and critical revision of the manuscript	substantial contribution to the biochemical work, interpretation of data, drafting and critical revision of the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5078898	27776477	AT	7	Acquisition, analysis, and interpretation of data, drafting, revising, and final approval of the manuscript, and agreement to be accountable for all aspects of the work	Acquisition, analysis, and interpretation of data, drafting, revising, and final approval of the manuscript, and agreement to be accountable for all aspects of the work	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5078898	27776477	BS	7	Acquisition, analysis, and interpretation of data, drafting, revising, and final approval of the manuscript, and agreement to be accountable for all aspects of the work	Acquisition, analysis, and interpretation of data, drafting, revising, and final approval of the manuscript, and agreement to be accountable for all aspects of the work	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5078898	27776477	CZ	7	Acquisition, analysis, and interpretation of data, drafting, revising, and final approval of the manuscript, and agreement to be accountable for all aspects of the work	Acquisition, analysis, and interpretation of data, drafting, revising, and final approval of the manuscript, and agreement to be accountable for all aspects of the work	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5078898	27776477	DZ	7	Acquisition, analysis, and interpretation of data, drafting, revising, and final approval of the manuscript, and agreement to be accountable for all aspects of the work	Acquisition, analysis, and interpretation of data, drafting, revising, and final approval of the manuscript, and agreement to be accountable for all aspects of the work	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5078898	27776477	FF	7	Acquisition, analysis, and interpretation of data, drafting, revising, and final approval of the manuscript, and agreement to be accountable for all aspects of the work	Acquisition, analysis, and interpretation of data, drafting, revising, and final approval of the manuscript, and agreement to be accountable for all aspects of the work	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5078898	27776477	JR	7	substantial contributions to conception and design, analysis, and interpretation of data, drafting, revising, and final approval of the manuscript, and agreement to be accountable for all aspects of the work	substantial contributions to conception and design, analysis, and interpretation of data, drafting, revising, and final approval of the manuscript, and agreement to be accountable for all aspects of the work	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5078898	27776477	LKA	7	Acquisition, analysis, and interpretation of data, drafting, revising, and final approval of the manuscript, and agreement to be accountable for all aspects of the work	Acquisition, analysis, and interpretation of data, drafting, revising, and final approval of the manuscript, and agreement to be accountable for all aspects of the work	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5078898	27776477	MST	7	substantial contributions to conception and design, analysis, and interpretation of data, drafting, revising, and final approval of the manuscript, and agreement to be accountable for all aspects of the work	substantial contributions to conception and design, analysis, and interpretation of data, drafting, revising, and final approval of the manuscript, and agreement to be accountable for all aspects of the work	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5078898	27776477	SI	7	substantial contributions to conception and design, analysis, and interpretation of data, drafting, revising, and final approval of the manuscript, and agreement to be accountable for all aspects of the work	substantial contributions to conception and design, analysis, and interpretation of data, drafting, revising, and final approval of the manuscript, and agreement to be accountable for all aspects of the work	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5078898	27776477	SR	7	substantial contributions to conception and design, analysis, and interpretation of data, drafting, revising, and final approval of the manuscript, and agreement to be accountable for all aspects of the work	substantial contributions to conception and design, analysis, and interpretation of data, drafting, revising, and final approval of the manuscript, and agreement to be accountable for all aspects of the work	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5078898	27776477	TJ	7	Acquisition, analysis, and interpretation of data, drafting, revising, and final approval of the manuscript, and agreement to be accountable for all aspects of the work	Acquisition, analysis, and interpretation of data, drafting, revising, and final approval of the manuscript, and agreement to be accountable for all aspects of the work	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5078898	27776477	TM	7	Acquisition, analysis, and interpretation of data, drafting, revising, and final approval of the manuscript, and agreement to be accountable for all aspects of the work	Acquisition, analysis, and interpretation of data, drafting, revising, and final approval of the manuscript, and agreement to be accountable for all aspects of the work	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
3852128	24321110	AW	2	collaborated in the design and oversight of the study|developed survey instruments|conducted statistical analysis|wrote the initial drafts of this manuscript	collaborated in the design and oversight of the study	Conceived and designed the experiments	Methodology|Supervision	YES
3852128	24321110	AW	2	collaborated in the design and oversight of the study|developed survey instruments|conducted statistical analysis|wrote the initial drafts of this manuscript	developed survey instruments	Performed the experiments	Investigation	YES
3852128	24321110	AW	2	collaborated in the design and oversight of the study|developed survey instruments|conducted statistical analysis|wrote the initial drafts of this manuscript	conducted statistical analysis	Analyzed the data	Formal analysis	YES
3852128	24321110	AW	2	collaborated in the design and oversight of the study|developed survey instruments|conducted statistical analysis|wrote the initial drafts of this manuscript	wrote the initial drafts of this manuscript	Wrote the paper	Writing - Original Draft	YES
3852128	24321110	All authors	2	had full access to the data and reviewed and edited the manuscript, and all take responsibility for its integrity as well as the accuracy of the analysis	had full access to the data and reviewed and edited the manuscript, and all take responsibility for its integrity as well as the accuracy of the analysis	Analyzed the data|Wrote the paper	Data curation|Formal analysis|Writing - Review & Editing	YES
3852128	24321110	CB	2	collaborated in the design and oversight of the study	collaborated in the design and oversight of the study	Conceived and designed the experiments	Methodology|Supervision	YES
3852128	24321110	DK	2	oversaw data collection	oversaw data collection	Performed the experiments	Investigation|Supervision	YES
3852128	24321110	EU	2	collaborated in the design and oversight of the study	collaborated in the design and oversight of the study	Conceived and designed the experiments	Methodology|Supervision	YES
3852128	24321110	GT	2	collaborated in the design and oversight of the study	collaborated in the design and oversight of the study	Conceived and designed the experiments	Methodology|Supervision	YES
3852128	24321110	MB	2	developed survey instruments	developed survey instruments	Performed the experiments	Investigation	YES
3852128	24321110	SB	2	collaborated in the design and oversight of the study|developed survey instruments	collaborated in the design and oversight of the study	Conceived and designed the experiments	Methodology|Supervision	YES
3852128	24321110	SB	2	collaborated in the design and oversight of the study|developed survey instruments	developed survey instruments	Performed the experiments	Investigation	YES
3852128	24321110	SK	2	conducted statistical analysis	conducted statistical analysis	Analyzed the data	Formal analysis	YES
3852128	24321110	VJ	2	developed survey instruments|oversaw data collection	developed survey instruments	Performed the experiments	Investigation	YES
3852128	24321110	VJ	2	developed survey instruments|oversaw data collection	oversaw data collection	Performed the experiments	Investigation|Supervision	YES
3362856	22655002	CK	1	Study design|Data collection	Study design	Conceived and designed the experiments	Methodology	YES
3362856	22655002	CK	1	Study design|Data collection	Data collection	Performed the experiments	Investigation	YES
4399982	25880729	AF	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399982	25880729	AF	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399982	25880729	AF	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399982	25880729	AS	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399982	25880729	DS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399982	25880729	DS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399982	25880729	DUT	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399982	25880729	FG	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399982	25880729	FG	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399982	25880729	FG	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399982	25880729	GT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399982	25880729	GT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399982	25880729	GT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399982	25880729	GT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399982	25880729	GT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399982	25880729	JS	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399982	25880729	LI	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399982	25880729	MP	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399982	25880729	VA	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399982	25880729	VA	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399982	25880729	YI	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399982	25880729	YI	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399982	25880729	YI	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1266348	16207371	RTs	2	that he previously purified, performed rnase h assays and prepared the initial draft of the manuscript	that he previously purified, performed rnase h assays and prepared the initial draft of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
1266348	16207371	VP	2	conceived of the study, participated in its design and coordination and helped to generate the final manuscript	conceived of the study, participated in its design and coordination and helped to generate the final manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Project administration|Writing - Review & Editing	YES
6156094	30270984	All authors	2	have given approval to the final version of the manuscript	have given approval to the final version of the manuscript	-	-	NO
5461763	28638388	HH	2	conducted experiments	conducted experiments	Performed the experiments	Investigation	YES
5461763	28638388	JCS	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5461763	28638388	JYG	2	designed experiments|conducted experiments|wrote the manuscript	designed experiments	Conceived and designed the experiments	Methodology	YES
5461763	28638388	JYG	2	designed experiments|conducted experiments|wrote the manuscript	conducted experiments	Performed the experiments	Investigation	YES
5461763	28638388	JYG	2	designed experiments|conducted experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5461763	28638388	KB	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5461763	28638388	QL	2	conducted experiments	conducted experiments	Performed the experiments	Investigation	YES
5461763	28638388	SCS	2	designed experiments|conducted experiments|wrote the manuscript	designed experiments	Conceived and designed the experiments	Methodology	YES
5461763	28638388	SCS	2	designed experiments|conducted experiments|wrote the manuscript	conducted experiments	Performed the experiments	Investigation	YES
5461763	28638388	SCS	2	designed experiments|conducted experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5461763	28638388	XLF	2	conducted experiments	conducted experiments	Performed the experiments	Investigation	YES
5078923	27776481	HH	PLoS52	conducted experiments|wrote the paper	conducted experiments	Performed the experiments	Investigation	YES
5078923	27776481	HH	PLoS52	conducted experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5078923	27776481	HY	PLoS52	conducted experiments	conducted experiments	Performed the experiments	Investigation	YES
5078923	27776481	KS	PLoS52	designed the research|wrote the paper	designed the research	Conceived and designed the experiments	Methodology	YES
5078923	27776481	KS	PLoS52	designed the research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5078923	27776481	MT	PLoS52	conducted experiments	conducted experiments	Performed the experiments	Investigation	YES
5078923	27776481	TT	PLoS52	designed the research|wrote the paper	designed the research	Conceived and designed the experiments	Methodology	YES
5078923	27776481	TT	PLoS52	designed the research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3852129	24321111	AS	1	Conceived and designed the study|Conducted data analysis|Contributed to draft of the paper	Conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3852129	24321111	AS	1	Conceived and designed the study|Conducted data analysis|Contributed to draft of the paper	Conducted data analysis	Analyzed the data	Formal analysis	YES
3852129	24321111	AS	1	Conceived and designed the study|Conducted data analysis|Contributed to draft of the paper	Contributed to draft of the paper	Wrote the paper	Writing - Original Draft	YES
3852129	24321111	DO	1	Conceived and designed the study	Conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3852129	24321111	EJS	1	Conceived and designed the study|Conducted data analysis|Contributed to draft of the paper	Conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3852129	24321111	EJS	1	Conceived and designed the study|Conducted data analysis|Contributed to draft of the paper	Conducted data analysis	Analyzed the data	Formal analysis	YES
3852129	24321111	EJS	1	Conceived and designed the study|Conducted data analysis|Contributed to draft of the paper	Contributed to draft of the paper	Wrote the paper	Writing - Original Draft	YES
3852129	24321111	EW	1	Conducted data analysis	Conducted data analysis	Analyzed the data	Formal analysis	YES
3852129	24321111	EvdE	1	Conceived and designed the study|Conducted data analysis|Contributed to draft of the paper	Conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3852129	24321111	EvdE	1	Conceived and designed the study|Conducted data analysis|Contributed to draft of the paper	Conducted data analysis	Analyzed the data	Formal analysis	YES
3852129	24321111	EvdE	1	Conceived and designed the study|Conducted data analysis|Contributed to draft of the paper	Contributed to draft of the paper	Wrote the paper	Writing - Original Draft	YES
3852129	24321111	GF	1	Conducted data analysis|Contributed to draft of the paper	Conducted data analysis	Analyzed the data	Formal analysis	YES
3852129	24321111	GF	1	Conducted data analysis|Contributed to draft of the paper	Contributed to draft of the paper	Wrote the paper	Writing - Original Draft	YES
3852129	24321111	NM	1	Conceived and designed the study	Conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3852129	24321111	SG	1	Contributed to draft of the paper	Contributed to draft of the paper	Wrote the paper	Writing - Original Draft	YES
1277814	16255776	FB	1	Concept protocol|Data analysis|Manuscript draft	Concept protocol	Conceived and designed the experiments	Conceptualization|Methodology	YES
1277814	16255776	FB	1	Concept protocol|Data analysis|Manuscript draft	Data analysis	Analyzed the data	Formal analysis	YES
1277814	16255776	FB	1	Concept protocol|Data analysis|Manuscript draft	Manuscript draft	Wrote the paper	Writing - Original Draft	YES
1277814	16255776	MM	1	Concept protocol|Data collection|Manuscript draft	Concept protocol	Conceived and designed the experiments	Conceptualization|Methodology	YES
1277814	16255776	MM	1	Concept protocol|Data collection|Manuscript draft	Data collection	Performed the experiments	Investigation	YES
1277814	16255776	MM	1	Concept protocol|Data collection|Manuscript draft	Manuscript draft	Wrote the paper	Writing - Original Draft	YES
4399983	25879658	EC	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399983	25879658	EC	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4399983	25879658	JC	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399983	25879658	JCK	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399983	25879658	JCK	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399983	25879658	JU	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4399983	25879658	KS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4399983	25879658	LKM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399983	25879658	LKM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399983	25879658	LKM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399983	25879658	LTMM	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399983	25879658	LTMM	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399983	25879658	MI	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4399983	25879658	PAB	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399983	25879658	PAB	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399983	25879658	PAB	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399983	25879658	SSVW	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399983	25879658	SSVW	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1277815	16219101	All authors	2	contributed to the writing of the manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
1277815	16219101	CX	2	performed all molecular assays	performed all molecular assays	Performed the experiments	Investigation	YES
1277815	16219101	DJA	2	was responsible for the overall experimental design and implementation of the project	was responsible for the overall experimental design and implementation of the project	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
1277815	16219101	JAP	2	processed samples, performed semen and wbc analyses and maintained databases	processed samples, performed semen and wbc analyses and maintained databases	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Formal analysis|Investigation|Software	YES
1277815	16219101	KHM	2	coordinated the procurement of semen and clinical information	coordinated the procurement of semen and clinical information	-	Project administration	YES
5078956	27776492	MMK	2	made substantial contributions to conception and design|acquired, interpreted and analyzed data|wrote the manuscript	made substantial contributions to conception and design	Conceived and designed the experiments	Conceptualization	YES
5078956	27776492	MMK	2	made substantial contributions to conception and design|acquired, interpreted and analyzed data|wrote the manuscript	acquired, interpreted and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5078956	27776492	MMK	2	made substantial contributions to conception and design|acquired, interpreted and analyzed data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5078956	27776492	MRW	2	made substantial contributions to conception and design|wrote the manuscript	made substantial contributions to conception and design	Conceived and designed the experiments	Conceptualization	YES
5078956	27776492	MRW	2	made substantial contributions to conception and design|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5078956	27776492	ZC	2	made substantial contributions to conception and design|acquired, interpreted and analyzed data|wrote the manuscript	made substantial contributions to conception and design	Conceived and designed the experiments	Conceptualization	YES
5078956	27776492	ZC	2	made substantial contributions to conception and design|acquired, interpreted and analyzed data|wrote the manuscript	acquired, interpreted and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5078956	27776492	ZC	2	made substantial contributions to conception and design|acquired, interpreted and analyzed data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3852130	24321113	CH	2	reviewed the final databases versions	reviewed the final databases versions	Contributed reagents/materials/analysis tools	Software	YES
3852130	24321113	EP	2	developed the conceptual framework and conducted the overall analysis of the study|led the execution of these methods|reviewed and extracted data from all studies obtained|led the writing of the manuscript|reviewed the final databases versions	developed the conceptual framework and conducted the overall analysis of the study	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
3852130	24321113	EP	2	developed the conceptual framework and conducted the overall analysis of the study|led the execution of these methods|reviewed and extracted data from all studies obtained|led the writing of the manuscript|reviewed the final databases versions	led the execution of these methods	Performed the experiments	Investigation	YES
3852130	24321113	EP	2	developed the conceptual framework and conducted the overall analysis of the study|led the execution of these methods|reviewed and extracted data from all studies obtained|led the writing of the manuscript|reviewed the final databases versions	reviewed and extracted data from all studies obtained	Performed the experiments	Investigation	YES
3852130	24321113	EP	2	developed the conceptual framework and conducted the overall analysis of the study|led the execution of these methods|reviewed and extracted data from all studies obtained|led the writing of the manuscript|reviewed the final databases versions	led the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
3852130	24321113	EP	2	developed the conceptual framework and conducted the overall analysis of the study|led the execution of these methods|reviewed and extracted data from all studies obtained|led the writing of the manuscript|reviewed the final databases versions	reviewed the final databases versions	Contributed reagents/materials/analysis tools	Software	YES
3852130	24321113	LA	2	reviewed and extracted data from all studies obtained	reviewed and extracted data from all studies obtained	Performed the experiments	Investigation	YES
3852130	24321113	SB	2	developed the conceptual framework and conducted the overall analysis of the study	developed the conceptual framework and conducted the overall analysis of the study	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
3852130	24321113	WCA	2	were instrumental in the interpretations of the results	were instrumental in the interpretations of the results	Analyzed the data	Formal analysis	YES
5462928	28642764	Both authors	2	have made substantial, direct and intellectual contribution to the work, and approved it for publication	have made substantial, direct and intellectual contribution to the work, and approved it for publication	-	-	NO
4399984	25880067	BL	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4399984	25880067	JL	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4399984	25880067	JN	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4399984	25880067	JZ	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399984	25880067	XW	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399984	25880067	XW	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399984	25880067	XW	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399984	25880067	XZ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
6001476	29457309	Claudio Ripellino	2	designed the research study, performed the research, collected and analyzed the data, and wrote the paper	designed the research study, performed the research, collected and analyzed the data, and wrote the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
6001476	29457309	Nazarena Cataldo	2	is acting as the submissions guarantor and takes responsibility for the integrity of the work as a whole, from inception to published article|designed the research study, performed the research, collected and analyzed the data, and wrote the paper	is acting as the submissions guarantor and takes responsibility for the integrity of the work as a whole, from inception to published article	-	-	NO
6001476	29457309	Nazarena Cataldo	2	is acting as the submissions guarantor and takes responsibility for the integrity of the work as a whole, from inception to published article|designed the research study, performed the research, collected and analyzed the data, and wrote the paper	designed the research study, performed the research, collected and analyzed the data, and wrote the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
6001476	29457309	Peter Malfertheiner	2	was responsible for clinical validation of the study and review of the manuscript	was responsible for clinical validation of the study and review of the manuscript	Performed the experiments|Wrote the paper	Validation|Writing - Review & Editing	YES
5080715	27782804	GGB	2	supervised the study and assisted in the preparation of the text and figures	supervised the study and assisted in the preparation of the text and figures	-	Supervision|Visualization	YES
5080715	27782804	LG	2	was responsible for the analysis of the bac sequence, all bioinformatic analysis, the analysis of gene expression, assembly of the tables and she assisted in the preparation of the text and figures	was responsible for the analysis of the bac sequence, all bioinformatic analysis, the analysis of gene expression, assembly of the tables and she assisted in the preparation of the text and figures	Performed the experiments	Formal analysis|Investigation|Visualization	YES
4399985	25879750	AN	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399985	25879750	AN	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399985	25879750	AN	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399985	25879750	CH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399985	25879750	CH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399985	25879750	CH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399985	25879750	CH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399985	25879750	CL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399985	25879750	CL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399985	25879750	CL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399985	25879750	JPS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399985	25879750	JPS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399985	25879750	JPS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399985	25879750	JPS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399985	25879750	MD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399985	25879750	MD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399985	25879750	MD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399985	25879750	MS	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399985	25879750	MS	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4399985	25879750	NG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399985	25879750	NG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4399985	25879750	NG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4399985	25879750	SB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399985	25879750	SB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399985	25879750	SB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5462932	28642761	AA	PLoS52	conceived and designed the experiments|contributed to the discussion of the results	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5462932	28642761	AA	PLoS52	conceived and designed the experiments|contributed to the discussion of the results	contributed to the discussion of the results	-	-	NO
5462932	28642761	AK	PLoS52	conceived and designed the experiments|performed hematoxylin assay|provided intellectual input and revised the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5462932	28642761	AK	PLoS52	conceived and designed the experiments|performed hematoxylin assay|provided intellectual input and revised the manuscript	performed hematoxylin assay	Performed the experiments	Investigation	YES
5462932	28642761	AK	PLoS52	conceived and designed the experiments|performed hematoxylin assay|provided intellectual input and revised the manuscript	provided intellectual input and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5462932	28642761	AR	PLoS52	conceived and designed the experiments|performed the in silico analysis|performed the abiotic stress assays|carried out the rt-qpcr assays and analyzed the data|performed hematoxylin assay|wrote the manuscript|contributed to the discussion of the results	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5462932	28642761	AR	PLoS52	conceived and designed the experiments|performed the in silico analysis|performed the abiotic stress assays|carried out the rt-qpcr assays and analyzed the data|performed hematoxylin assay|wrote the manuscript|contributed to the discussion of the results	performed the in silico analysis	Performed the experiments	Formal analysis|Investigation	YES
5462932	28642761	AR	PLoS52	conceived and designed the experiments|performed the in silico analysis|performed the abiotic stress assays|carried out the rt-qpcr assays and analyzed the data|performed hematoxylin assay|wrote the manuscript|contributed to the discussion of the results	performed the abiotic stress assays	Performed the experiments	Investigation	YES
5462932	28642761	AR	PLoS52	conceived and designed the experiments|performed the in silico analysis|performed the abiotic stress assays|carried out the rt-qpcr assays and analyzed the data|performed hematoxylin assay|wrote the manuscript|contributed to the discussion of the results	carried out the rt-qpcr assays and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5462932	28642761	AR	PLoS52	conceived and designed the experiments|performed the in silico analysis|performed the abiotic stress assays|carried out the rt-qpcr assays and analyzed the data|performed hematoxylin assay|wrote the manuscript|contributed to the discussion of the results	performed hematoxylin assay	Performed the experiments	Investigation	YES
5462932	28642761	AR	PLoS52	conceived and designed the experiments|performed the in silico analysis|performed the abiotic stress assays|carried out the rt-qpcr assays and analyzed the data|performed hematoxylin assay|wrote the manuscript|contributed to the discussion of the results	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5462932	28642761	AR	PLoS52	conceived and designed the experiments|performed the in silico analysis|performed the abiotic stress assays|carried out the rt-qpcr assays and analyzed the data|performed hematoxylin assay|wrote the manuscript|contributed to the discussion of the results	contributed to the discussion of the results	-	-	NO
5462932	28642761	BC	PLoS52	carried out the rt-qpcr assays and analyzed the data	carried out the rt-qpcr assays and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5462932	28642761	CS	PLoS52	contributed to the discussion of the results	contributed to the discussion of the results	-	-	NO
5462932	28642761	DC	PLoS52	performed and analyzed the organic acids	performed and analyzed the organic acids	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5462932	28642761	FV	PLoS52	performed the abiotic stress assays|carried out the rt-qpcr assays and analyzed the data	performed the abiotic stress assays	Performed the experiments	Investigation	YES
5462932	28642761	FV	PLoS52	performed the abiotic stress assays|carried out the rt-qpcr assays and analyzed the data	carried out the rt-qpcr assays and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5462932	28642761	GC	PLoS52	contributed to the discussion of the results|provided intellectual input and revised the manuscript	contributed to the discussion of the results	-	-	NO
5462932	28642761	GC	PLoS52	contributed to the discussion of the results|provided intellectual input and revised the manuscript	provided intellectual input and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5462932	28642761	HM	PLoS52	conceived and designed the experiments|performed and analyzed the organic acids|provided intellectual input and revised the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5462932	28642761	HM	PLoS52	conceived and designed the experiments|performed and analyzed the organic acids|provided intellectual input and revised the manuscript	performed and analyzed the organic acids	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5462932	28642761	HM	PLoS52	conceived and designed the experiments|performed and analyzed the organic acids|provided intellectual input and revised the manuscript	provided intellectual input and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5462932	28642761	JVM	PLoS52	contributed to the discussion of the results	contributed to the discussion of the results	-	-	NO
5462932	28642761	KD	PLoS52	performed the abiotic stress assays	performed the abiotic stress assays	Performed the experiments	Investigation	YES
5462932	28642761	MB	PLoS52	performed and analyzed the organic acids|contributed to the discussion of the results	performed and analyzed the organic acids	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5462932	28642761	MB	PLoS52	performed and analyzed the organic acids|contributed to the discussion of the results	contributed to the discussion of the results	-	-	NO
5462932	28642761	PAO	PLoS52	performed and analyzed the organic acids	performed and analyzed the organic acids	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5462932	28642761	PM	PLoS52	conceived and designed the experiments|performed the in silico analysis|performed hematoxylin assay	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5462932	28642761	PM	PLoS52	conceived and designed the experiments|performed the in silico analysis|performed hematoxylin assay	performed the in silico analysis	Performed the experiments	Formal analysis|Investigation	YES
5462932	28642761	PM	PLoS52	conceived and designed the experiments|performed the in silico analysis|performed hematoxylin assay	performed hematoxylin assay	Performed the experiments	Investigation	YES
5462932	28642761	RC	PLoS52	performed and analyzed the organic acids	performed and analyzed the organic acids	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5462932	28642761	WRS	PLoS52	conceived and designed the experiments|performed the abiotic stress assays|performed hematoxylin assay|performed and analyzed the organic acids|wrote the manuscript|contributed to the discussion of the results	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5462932	28642761	WRS	PLoS52	conceived and designed the experiments|performed the abiotic stress assays|performed hematoxylin assay|performed and analyzed the organic acids|wrote the manuscript|contributed to the discussion of the results	performed the abiotic stress assays	Performed the experiments	Investigation	YES
5462932	28642761	WRS	PLoS52	conceived and designed the experiments|performed the abiotic stress assays|performed hematoxylin assay|performed and analyzed the organic acids|wrote the manuscript|contributed to the discussion of the results	performed hematoxylin assay	Performed the experiments	Investigation	YES
5462932	28642761	WRS	PLoS52	conceived and designed the experiments|performed the abiotic stress assays|performed hematoxylin assay|performed and analyzed the organic acids|wrote the manuscript|contributed to the discussion of the results	performed and analyzed the organic acids	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5462932	28642761	WRS	PLoS52	conceived and designed the experiments|performed the abiotic stress assays|performed hematoxylin assay|performed and analyzed the organic acids|wrote the manuscript|contributed to the discussion of the results	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5462932	28642761	WRS	PLoS52	conceived and designed the experiments|performed the abiotic stress assays|performed hematoxylin assay|performed and analyzed the organic acids|wrote the manuscript|contributed to the discussion of the results	contributed to the discussion of the results	-	-	NO
1395319	16480525	ACvdK	2	participated in the design of the study, carried out the statistical analyses and drafted the manuscript	participated in the design of the study, carried out the statistical analyses and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5462948	28642768	AG	2	involved in planning the field and greenhouse experiments	involved in planning the field and greenhouse experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5462948	28642768	CL	2	participated in greenhouse experiment and silicon quantification|involved in data analysis	participated in greenhouse experiment and silicon quantification	Performed the experiments	Investigation	YES
5462948	28642768	CL	2	participated in greenhouse experiment and silicon quantification|involved in data analysis	involved in data analysis	Analyzed the data	Formal analysis	YES
5462948	28642768	JL	2	involved in data analysis	involved in data analysis	Analyzed the data	Formal analysis	YES
5462948	28642768	LG	2	involved in planning the field and greenhouse experiments	involved in planning the field and greenhouse experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5462948	28642768	MD	2	involved in planning the field and greenhouse experiments	involved in planning the field and greenhouse experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5462948	28642768	MG	2	performed all the greenhouse and field experiments	performed all the greenhouse and field experiments	Performed the experiments	Investigation	YES
5462948	28642768	RB	2	designed and directed the project	designed and directed the project	Conceived and designed the experiments	Methodology|Supervision	YES
5462948	28642768	RD	2	performed the bioinformatic analysis	performed the bioinformatic analysis	Performed the experiments	Formal analysis|Investigation	YES
5462948	28642768	SO	2	performed all the greenhouse and field experiments	performed all the greenhouse and field experiments	Performed the experiments	Investigation	YES
5080751	27784286	AQR	2	performed molecular biology and genetic mapping experiments	performed molecular biology and genetic mapping experiments	Performed the experiments	Investigation	YES
5080751	27784286	BLD	2	wrote the manuscript|performed comparative genomics|interpreted mapping data	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5080751	27784286	BLD	2	wrote the manuscript|performed comparative genomics|interpreted mapping data	performed comparative genomics	Performed the experiments	Investigation	YES
5080751	27784286	BLD	2	wrote the manuscript|performed comparative genomics|interpreted mapping data	interpreted mapping data	Analyzed the data	Formal analysis	YES
5080751	27784286	KPC	2	analyzed ddradseq data|interpreted mapping data	analyzed ddradseq data	Analyzed the data	Formal analysis	YES
5080751	27784286	KPC	2	analyzed ddradseq data|interpreted mapping data	interpreted mapping data	Analyzed the data	Formal analysis	YES
5080751	27784286	MKS	2	performed animal husbandry and dissections|performed molecular biology and genetic mapping experiments	performed animal husbandry and dissections	Performed the experiments	Investigation	YES
5080751	27784286	MKS	2	performed animal husbandry and dissections|performed molecular biology and genetic mapping experiments	performed molecular biology and genetic mapping experiments	Performed the experiments	Investigation	YES
5080751	27784286	NBR	2	designed the study|wrote the manuscript|performed animal husbandry and dissections|performed molecular biology and genetic mapping experiments|produced ddradseq libraries|interpreted mapping data	designed the study	Conceived and designed the experiments	Methodology	YES
5080751	27784286	NBR	2	designed the study|wrote the manuscript|performed animal husbandry and dissections|performed molecular biology and genetic mapping experiments|produced ddradseq libraries|interpreted mapping data	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5080751	27784286	NBR	2	designed the study|wrote the manuscript|performed animal husbandry and dissections|performed molecular biology and genetic mapping experiments|produced ddradseq libraries|interpreted mapping data	performed animal husbandry and dissections	Performed the experiments	Investigation	YES
5080751	27784286	NBR	2	designed the study|wrote the manuscript|performed animal husbandry and dissections|performed molecular biology and genetic mapping experiments|produced ddradseq libraries|interpreted mapping data	performed molecular biology and genetic mapping experiments	Performed the experiments	Investigation	YES
5080751	27784286	NBR	2	designed the study|wrote the manuscript|performed animal husbandry and dissections|performed molecular biology and genetic mapping experiments|produced ddradseq libraries|interpreted mapping data	produced ddradseq libraries	-	-	NO
5080751	27784286	NBR	2	designed the study|wrote the manuscript|performed animal husbandry and dissections|performed molecular biology and genetic mapping experiments|produced ddradseq libraries|interpreted mapping data	interpreted mapping data	Analyzed the data	Formal analysis	YES
5080751	27784286	RBR	2	designed the study|wrote the manuscript|interpreted mapping data	designed the study	Conceived and designed the experiments	Methodology	YES
5080751	27784286	RBR	2	designed the study|wrote the manuscript|interpreted mapping data	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5080751	27784286	RBR	2	designed the study|wrote the manuscript|interpreted mapping data	interpreted mapping data	Analyzed the data	Formal analysis	YES
5080751	27784286	RDF	2	designed the study|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5080751	27784286	RDF	2	designed the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5080751	27784286	SAJ	2	designed the study|wrote the manuscript|performed animal husbandry and dissections	designed the study	Conceived and designed the experiments	Methodology	YES
5080751	27784286	SAJ	2	designed the study|wrote the manuscript|performed animal husbandry and dissections	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5080751	27784286	SAJ	2	designed the study|wrote the manuscript|performed animal husbandry and dissections	performed animal husbandry and dissections	Performed the experiments	Investigation	YES
4399987	25880732	JC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Participated in data interpretation|Contributed substantially to the scientific process leading up to the writing of the submitted manuscript|Approved of the final version	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399987	25880732	JC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Participated in data interpretation|Contributed substantially to the scientific process leading up to the writing of the submitted manuscript|Approved of the final version	Performed the experiments	Performed the experiments	Investigation	YES
4399987	25880732	JC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Participated in data interpretation|Contributed substantially to the scientific process leading up to the writing of the submitted manuscript|Approved of the final version	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399987	25880732	JC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Participated in data interpretation|Contributed substantially to the scientific process leading up to the writing of the submitted manuscript|Approved of the final version	Participated in data interpretation	Analyzed the data	Formal analysis	YES
4399987	25880732	JC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Participated in data interpretation|Contributed substantially to the scientific process leading up to the writing of the submitted manuscript|Approved of the final version	Contributed substantially to the scientific process leading up to the writing of the submitted manuscript	Wrote the paper	Writing - Original Draft	YES
4399987	25880732	JC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Participated in data interpretation|Contributed substantially to the scientific process leading up to the writing of the submitted manuscript|Approved of the final version	Approved of the final version	-	-	NO
4399987	25880732	LA	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Participated in data interpretation|Contributed substantially to the scientific process leading up to the writing of the submitted manuscript|Approved of the final version	Analyzed the data	Analyzed the data	Formal analysis	YES
4399987	25880732	LA	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Participated in data interpretation|Contributed substantially to the scientific process leading up to the writing of the submitted manuscript|Approved of the final version	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399987	25880732	LA	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Participated in data interpretation|Contributed substantially to the scientific process leading up to the writing of the submitted manuscript|Approved of the final version	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399987	25880732	LA	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Participated in data interpretation|Contributed substantially to the scientific process leading up to the writing of the submitted manuscript|Approved of the final version	Participated in data interpretation	Analyzed the data	Formal analysis	YES
4399987	25880732	LA	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Participated in data interpretation|Contributed substantially to the scientific process leading up to the writing of the submitted manuscript|Approved of the final version	Contributed substantially to the scientific process leading up to the writing of the submitted manuscript	Wrote the paper	Writing - Original Draft	YES
4399987	25880732	LA	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Participated in data interpretation|Contributed substantially to the scientific process leading up to the writing of the submitted manuscript|Approved of the final version	Approved of the final version	-	-	NO
4399987	25880732	NCS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Participated in data interpretation|Contributed substantially to the scientific process leading up to the writing of the submitted manuscript|Approved of the final version	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399987	25880732	NCS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Participated in data interpretation|Contributed substantially to the scientific process leading up to the writing of the submitted manuscript|Approved of the final version	Performed the experiments	Performed the experiments	Investigation	YES
4399987	25880732	NCS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Participated in data interpretation|Contributed substantially to the scientific process leading up to the writing of the submitted manuscript|Approved of the final version	Analyzed the data	Analyzed the data	Formal analysis	YES
4399987	25880732	NCS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Participated in data interpretation|Contributed substantially to the scientific process leading up to the writing of the submitted manuscript|Approved of the final version	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399987	25880732	NCS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Participated in data interpretation|Contributed substantially to the scientific process leading up to the writing of the submitted manuscript|Approved of the final version	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399987	25880732	NCS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Participated in data interpretation|Contributed substantially to the scientific process leading up to the writing of the submitted manuscript|Approved of the final version	Participated in data interpretation	Analyzed the data	Formal analysis	YES
4399987	25880732	NCS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Participated in data interpretation|Contributed substantially to the scientific process leading up to the writing of the submitted manuscript|Approved of the final version	Contributed substantially to the scientific process leading up to the writing of the submitted manuscript	Wrote the paper	Writing - Original Draft	YES
4399987	25880732	NCS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Participated in data interpretation|Contributed substantially to the scientific process leading up to the writing of the submitted manuscript|Approved of the final version	Approved of the final version	-	-	NO
4399987	25880732	NS	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Participated in data interpretation|Contributed substantially to the scientific process leading up to the writing of the submitted manuscript|Approved of the final version	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399987	25880732	NS	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Participated in data interpretation|Contributed substantially to the scientific process leading up to the writing of the submitted manuscript|Approved of the final version	Performed the experiments	Performed the experiments	Investigation	YES
4399987	25880732	NS	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Participated in data interpretation|Contributed substantially to the scientific process leading up to the writing of the submitted manuscript|Approved of the final version	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399987	25880732	NS	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Participated in data interpretation|Contributed substantially to the scientific process leading up to the writing of the submitted manuscript|Approved of the final version	Participated in data interpretation	Analyzed the data	Formal analysis	YES
4399987	25880732	NS	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Participated in data interpretation|Contributed substantially to the scientific process leading up to the writing of the submitted manuscript|Approved of the final version	Contributed substantially to the scientific process leading up to the writing of the submitted manuscript	Wrote the paper	Writing - Original Draft	YES
4399987	25880732	NS	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Participated in data interpretation|Contributed substantially to the scientific process leading up to the writing of the submitted manuscript|Approved of the final version	Approved of the final version	-	-	NO
4399987	25880732	PC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Participated in data interpretation|Contributed substantially to the scientific process leading up to the writing of the submitted manuscript|Approved of the final version	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399987	25880732	PC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Participated in data interpretation|Contributed substantially to the scientific process leading up to the writing of the submitted manuscript|Approved of the final version	Performed the experiments	Performed the experiments	Investigation	YES
4399987	25880732	PC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Participated in data interpretation|Contributed substantially to the scientific process leading up to the writing of the submitted manuscript|Approved of the final version	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399987	25880732	PC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Participated in data interpretation|Contributed substantially to the scientific process leading up to the writing of the submitted manuscript|Approved of the final version	Participated in data interpretation	Analyzed the data	Formal analysis	YES
4399987	25880732	PC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Participated in data interpretation|Contributed substantially to the scientific process leading up to the writing of the submitted manuscript|Approved of the final version	Contributed substantially to the scientific process leading up to the writing of the submitted manuscript	Wrote the paper	Writing - Original Draft	YES
4399987	25880732	PC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Participated in data interpretation|Contributed substantially to the scientific process leading up to the writing of the submitted manuscript|Approved of the final version	Approved of the final version	-	-	NO
4399987	25880732	PSC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Participated in data interpretation|Contributed substantially to the scientific process leading up to the writing of the submitted manuscript|Approved of the final version	Analyzed the data	Analyzed the data	Formal analysis	YES
4399987	25880732	PSC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Participated in data interpretation|Contributed substantially to the scientific process leading up to the writing of the submitted manuscript|Approved of the final version	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399987	25880732	PSC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Participated in data interpretation|Contributed substantially to the scientific process leading up to the writing of the submitted manuscript|Approved of the final version	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399987	25880732	PSC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Participated in data interpretation|Contributed substantially to the scientific process leading up to the writing of the submitted manuscript|Approved of the final version	Participated in data interpretation	Analyzed the data	Formal analysis	YES
4399987	25880732	PSC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Participated in data interpretation|Contributed substantially to the scientific process leading up to the writing of the submitted manuscript|Approved of the final version	Contributed substantially to the scientific process leading up to the writing of the submitted manuscript	Wrote the paper	Writing - Original Draft	YES
4399987	25880732	PSC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Participated in data interpretation|Contributed substantially to the scientific process leading up to the writing of the submitted manuscript|Approved of the final version	Approved of the final version	-	-	NO
4399987	25880732	PSM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Participated in data interpretation|Contributed substantially to the scientific process leading up to the writing of the submitted manuscript|Approved of the final version	Analyzed the data	Analyzed the data	Formal analysis	YES
4399987	25880732	PSM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Participated in data interpretation|Contributed substantially to the scientific process leading up to the writing of the submitted manuscript|Approved of the final version	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399987	25880732	PSM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Participated in data interpretation|Contributed substantially to the scientific process leading up to the writing of the submitted manuscript|Approved of the final version	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399987	25880732	PSM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Participated in data interpretation|Contributed substantially to the scientific process leading up to the writing of the submitted manuscript|Approved of the final version	Participated in data interpretation	Analyzed the data	Formal analysis	YES
4399987	25880732	PSM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Participated in data interpretation|Contributed substantially to the scientific process leading up to the writing of the submitted manuscript|Approved of the final version	Contributed substantially to the scientific process leading up to the writing of the submitted manuscript	Wrote the paper	Writing - Original Draft	YES
4399987	25880732	PSM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Participated in data interpretation|Contributed substantially to the scientific process leading up to the writing of the submitted manuscript|Approved of the final version	Approved of the final version	-	-	NO
6251563	30487664	S These	2	authors contributed equally to this work	authors contributed equally to this work	-	-	NO
4429214	26064928	Inga Potapova	2	contributed equally	contributed equally	-	-	NO
4429214	26064928	Vincent A. Stadelmann	2	contributed equally	contributed equally	-	-	NO
3852353	24321117	AG	2	developed the analytic strategy and completed data analysis	developed the analytic strategy and completed data analysis	Analyzed the data	Formal analysis	YES
3852353	24321117	CEK	2	conceptualized and designed the study|developed the analytic strategy and completed data analysis|drafted the manuscript, with all authors providing critical inputs for the interpretation of the results	conceptualized and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3852353	24321117	CEK	2	conceptualized and designed the study|developed the analytic strategy and completed data analysis|drafted the manuscript, with all authors providing critical inputs for the interpretation of the results	developed the analytic strategy and completed data analysis	Analyzed the data	Formal analysis	YES
3852353	24321117	CEK	2	conceptualized and designed the study|developed the analytic strategy and completed data analysis|drafted the manuscript, with all authors providing critical inputs for the interpretation of the results	drafted the manuscript, with all authors providing critical inputs for the interpretation of the results	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3852353	24321117	DA	2	conceptualized and designed the study|drafted the manuscript, with all authors providing critical inputs for the interpretation of the results	conceptualized and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3852353	24321117	DA	2	conceptualized and designed the study|drafted the manuscript, with all authors providing critical inputs for the interpretation of the results	drafted the manuscript, with all authors providing critical inputs for the interpretation of the results	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3852353	24321117	DLK	2	conceptualized and designed the study	conceptualized and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3852353	24321117	JLG	2	conceptualized and designed the study|developed the analytic strategy and completed data analysis	conceptualized and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3852353	24321117	JLG	2	conceptualized and designed the study|developed the analytic strategy and completed data analysis	developed the analytic strategy and completed data analysis	Analyzed the data	Formal analysis	YES
3852353	24321117	SDB	2	conceptualized and designed the study|developed the analytic strategy and completed data analysis|drafted the manuscript, with all authors providing critical inputs for the interpretation of the results	conceptualized and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3852353	24321117	SDB	2	conceptualized and designed the study|developed the analytic strategy and completed data analysis|drafted the manuscript, with all authors providing critical inputs for the interpretation of the results	developed the analytic strategy and completed data analysis	Analyzed the data	Formal analysis	YES
3852353	24321117	SDB	2	conceptualized and designed the study|developed the analytic strategy and completed data analysis|drafted the manuscript, with all authors providing critical inputs for the interpretation of the results	drafted the manuscript, with all authors providing critical inputs for the interpretation of the results	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3852353	24321117	SK	2	developed the analytic strategy and completed data analysis	developed the analytic strategy and completed data analysis	Analyzed the data	Formal analysis	YES
3852353	24321117	ZM	2	conceptualized and designed the study	conceptualized and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399989	25880318	CAML	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399989	25880318	CAML	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399989	25880318	CAML	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399989	25880318	CAML	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399989	25880318	FO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399989	25880318	FO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399989	25880318	FO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399989	25880318	FO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399989	25880318	MBA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399989	25880318	MBA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399989	25880318	MBA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399989	25880318	MBA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399989	25880318	MBA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399989	25880318	VSM	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5462954	28642771	AC-L	PLoS52	provided the idea of the work|designed the experiments|participated in the interpretation of results and critically reviewed the manuscript	provided the idea of the work	Conceived and designed the experiments	Conceptualization	YES
5462954	28642771	AC-L	PLoS52	provided the idea of the work|designed the experiments|participated in the interpretation of results and critically reviewed the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5462954	28642771	AC-L	PLoS52	provided the idea of the work|designed the experiments|participated in the interpretation of results and critically reviewed the manuscript	participated in the interpretation of results and critically reviewed the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5462954	28642771	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5462954	28642771	EC	PLoS52	performed the identification of the phytopathogen	performed the identification of the phytopathogen	Performed the experiments	Investigation	YES
5462954	28642771	JV	PLoS52	performed the bioinformatics analysis|performed qrt pcr assays|participated in the interpretation of results and critically reviewed the manuscript	performed the bioinformatics analysis	Performed the experiments	Formal analysis|Investigation	YES
5462954	28642771	JV	PLoS52	performed the bioinformatics analysis|performed qrt pcr assays|participated in the interpretation of results and critically reviewed the manuscript	performed qrt pcr assays	Performed the experiments	Investigation	YES
5462954	28642771	JV	PLoS52	performed the bioinformatics analysis|performed qrt pcr assays|participated in the interpretation of results and critically reviewed the manuscript	participated in the interpretation of results and critically reviewed the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5462954	28642771	LH	PLoS52	contributed in the sequencing and generation of libraries|participated in the interpretation of results and critically reviewed the manuscript	contributed in the sequencing and generation of libraries	Performed the experiments	Investigation	YES
5462954	28642771	LH	PLoS52	contributed in the sequencing and generation of libraries|participated in the interpretation of results and critically reviewed the manuscript	participated in the interpretation of results and critically reviewed the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5462954	28642771	LX	PLoS52	designed the experiments|performed the bioinformatics analysis|performed qrt pcr assays|participated in the interpretation of results and critically reviewed the manuscript|wrote the paper	designed the experiments	Conceived and designed the experiments	Methodology	YES
5462954	28642771	LX	PLoS52	designed the experiments|performed the bioinformatics analysis|performed qrt pcr assays|participated in the interpretation of results and critically reviewed the manuscript|wrote the paper	performed the bioinformatics analysis	Performed the experiments	Formal analysis|Investigation	YES
5462954	28642771	LX	PLoS52	designed the experiments|performed the bioinformatics analysis|performed qrt pcr assays|participated in the interpretation of results and critically reviewed the manuscript|wrote the paper	performed qrt pcr assays	Performed the experiments	Investigation	YES
5462954	28642771	LX	PLoS52	designed the experiments|performed the bioinformatics analysis|performed qrt pcr assays|participated in the interpretation of results and critically reviewed the manuscript|wrote the paper	participated in the interpretation of results and critically reviewed the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5462954	28642771	LX	PLoS52	designed the experiments|performed the bioinformatics analysis|performed qrt pcr assays|participated in the interpretation of results and critically reviewed the manuscript|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5462954	28642771	PG	PLoS52	contributed with the in vivo assays in fruit	contributed with the in vivo assays in fruit	Performed the experiments	Investigation	YES
5462954	28642771	SG	PLoS52	performed the bioinformatics analysis	performed the bioinformatics analysis	Performed the experiments	Formal analysis|Investigation	YES
5462954	28642771	The authors	PLoS52	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	Performed the experiments	Investigation	YES
5462954	28642771	UL	PLoS52	contributed with the in vivo assays in fruit	contributed with the in vivo assays in fruit	Performed the experiments	Investigation	YES
4399992	25879926	APF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4399992	25879926	APF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4399992	25879926	APF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4399992	25879926	APF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399992	25879926	APF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399992	25879926	HMA	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399992	25879926	HMA	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4399992	25879926	JCS	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4399992	25879926	JCS	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3852354	24321115	CB	2	provided technical oversight for the implementation, data analysis and manuscript development	provided technical oversight for the implementation, data analysis and manuscript development	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources|Supervision	YES
3852354	24321115	DD	2	conceptualized the study|provided management of the research implementation and field teams and supported writing sections of the manuscript	conceptualized the study	Conceived and designed the experiments	Conceptualization	YES
3852354	24321115	DD	2	conceptualized the study|provided management of the research implementation and field teams and supported writing sections of the manuscript	provided management of the research implementation and field teams and supported writing sections of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3852354	24321115	EC	2	conducted the data analysis and led the writing of the manuscript	conducted the data analysis and led the writing of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3852354	24321115	FD	2	provided management of the research implementation and field teams and supported writing sections of the manuscript	provided management of the research implementation and field teams and supported writing sections of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3852354	24321115	FM	2	conceptualized the study	conceptualized the study	Conceived and designed the experiments	Conceptualization	YES
3852354	24321115	MN	2	conceptualized the study	conceptualized the study	Conceived and designed the experiments	Conceptualization	YES
3852354	24321115	SB	2	conceptualized the study|provided technical oversight for the implementation, data analysis and manuscript development	conceptualized the study	Conceived and designed the experiments	Conceptualization	YES
3852354	24321115	SB	2	conceptualized the study|provided technical oversight for the implementation, data analysis and manuscript development	provided technical oversight for the implementation, data analysis and manuscript development	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources|Supervision	YES
1435917	16504023	BB	2	were involved in study design, conduct and manuscript writing	were involved in study design, conduct and manuscript writing	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
1435917	16504023	CM	2	were involved in data analysis, interpretation and manuscript writing	were involved in data analysis, interpretation and manuscript writing	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
1435917	16504023	DS	2	contributed to data collection and manuscript preparation	contributed to data collection and manuscript preparation	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
1435917	16504023	GF	2	were involved in data analysis, interpretation and manuscript writing	were involved in data analysis, interpretation and manuscript writing	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
1435917	16504023	JS	2	contributed to study design, data collection, data interpretation and manuscript preparation	contributed to study design, data collection, data interpretation and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
1435917	16504023	KJ	2	were involved in study design, conduct and manuscript writing	were involved in study design, conduct and manuscript writing	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
1435917	16504023	MS	2	contributed to study design and critical revising for important intellectual content	contributed to study design and critical revising for important intellectual content	Conceived and designed the experiments	Methodology	YES
1435917	16504023	PA	2	contributed to study design and critical revising for important intellectual content|were involved in laboratory procedures and manuscript writing	contributed to study design and critical revising for important intellectual content	Conceived and designed the experiments	Methodology	YES
1435917	16504023	PA	2	contributed to study design and critical revising for important intellectual content|were involved in laboratory procedures and manuscript writing	were involved in laboratory procedures and manuscript writing	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
1435917	16504023	RA	2	were involved in laboratory procedures and manuscript writing	were involved in laboratory procedures and manuscript writing	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
1435917	16504023	RSJ	2	was involved in study design, conduct and critical review of the manuscript for its intellectual contents	was involved in study design, conduct and critical review of the manuscript for its intellectual contents	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
1435917	16504023	SL	2	was involved in study design, conduct and manuscript writing	was involved in study design, conduct and manuscript writing	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5462955	28642784	AH	2	provided data and contributed to the material and method parts and thus supporting the creation of the life cycle inventory	provided data and contributed to the material and method parts and thus supporting the creation of the life cycle inventory	Performed the experiments|Contributed reagents/materials/analysis tools	Resources	YES
5462955	28642784	AK	2	provided data and contributed to the material and method parts and thus supporting the creation of the life cycle inventory|the discussion of the results	provided data and contributed to the material and method parts and thus supporting the creation of the life cycle inventory	Performed the experiments|Contributed reagents/materials/analysis tools	Resources	YES
5462955	28642784	AK	2	provided data and contributed to the material and method parts and thus supporting the creation of the life cycle inventory|the discussion of the results	the discussion of the results	-	-	NO
5462955	28642784	IL	2	added valuable contribution to each chapter and in manifold discussions	added valuable contribution to each chapter and in manifold discussions	-	-	NO
5462955	28642784	MW	2	was performing the lca modeling and was leading the writing process	was performing the lca modeling and was leading the writing process	Performed the experiments|Wrote the paper	Investigation|Methodology	YES
5462955	28642784	YI	2	provided data and contributed to the material and method parts and thus supporting the creation of the life cycle inventory	provided data and contributed to the material and method parts and thus supporting the creation of the life cycle inventory	Performed the experiments|Contributed reagents/materials/analysis tools	Resources	YES
6345103	30686858	A.I.	2	performed the viscosity measurements	performed the viscosity measurements	Performed the experiments	Investigation	YES
6345103	30686858	A.v.B.	2	performed the viscosity measurements	performed the viscosity measurements	Performed the experiments	Investigation	YES
6345103	30686858	All authors	2	have given approval to the final version of the manuscript	have given approval to the final version of the manuscript	-	-	NO
6345103	30686858	D.T.W.	2	performed the viscosity measurements	performed the viscosity measurements	Performed the experiments	Investigation	YES
6345103	30686858	F.H.	2	authors contributed equally|performed the viscosity measurements|performed the cryo-sem and cryo-tem experiments	authors contributed equally	-	-	NO
6345103	30686858	F.H.	2	authors contributed equally|performed the viscosity measurements|performed the cryo-sem and cryo-tem experiments	performed the viscosity measurements	Performed the experiments	Investigation	YES
6345103	30686858	F.H.	2	authors contributed equally|performed the viscosity measurements|performed the cryo-sem and cryo-tem experiments	performed the cryo-sem and cryo-tem experiments	Performed the experiments	Investigation	YES
6345103	30686858	J.D.M.	2	performed the cryo-sem and cryo-tem experiments	performed the cryo-sem and cryo-tem experiments	Performed the experiments	Investigation	YES
6345103	30686858	M.d.W.	2	performed the cryo-sem and cryo-tem experiments	performed the cryo-sem and cryo-tem experiments	Performed the experiments	Investigation	YES
6345103	30686858	R.K.P.	2	authors contributed equally	authors contributed equally	-	-	NO
4400006	25879533	MK	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400006	25879533	MM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400006	25879533	MM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400006	25879533	MM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400006	25879533	MM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400006	25879533	MM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400006	25879533	NM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4400006	25879533	TH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400006	25879533	TH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400006	25879533	TH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400006	25879533	TH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400006	25879533	YH	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400006	25879533	YH	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3551235	23346266	Anneke L. Francke	2	contributed to the conception and design of the study and the manuscript, supervision of analysis of the data and drafting the manuscript|reviewed the paper	contributed to the conception and design of the study and the manuscript, supervision of analysis of the data and drafting the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Methodology|Resources|Supervision|Writing - Original Draft	YES
3551235	23346266	Anneke L. Francke	2	contributed to the conception and design of the study and the manuscript, supervision of analysis of the data and drafting the manuscript|reviewed the paper	reviewed the paper	Wrote the paper	Writing - Review & Editing	YES
3551235	23346266	H.C.M.	2	did the acquisition of subjects and commentated on the findings of the study	did the acquisition of subjects and commentated on the findings of the study	-	-	NO
3551235	23346266	Marieke Zwaanswijk	2	conducted the conception and design of the study, data analysis and interpretation on the data, drafting and preparation of the manuscript	conducted the conception and design of the study, data analysis and interpretation on the data, drafting and preparation of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5080790	27782803	BKW	2	did site-directed mutagenesis and contributed to atro-box peptide design for the array	did site-directed mutagenesis and contributed to atro-box peptide design for the array	Conceived and designed the experiments|Performed the experiments	Investigation|Supervision	YES
5080790	27782803	CDL	2	generated nr2e1 wild-type construct and contributed to statistical analysis	generated nr2e1 wild-type construct and contributed to statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5080790	27782803	DM	2	performed marconi experiments	performed marconi experiments	Performed the experiments	Investigation	YES
5080790	27782803	EMS	2	conceived the study|participated in the study design|helped with the drafted the paper with	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5080790	27782803	EMS	2	conceived the study|participated in the study design|helped with the drafted the paper with	participated in the study design	Conceived and designed the experiments	Methodology	YES
5080790	27782803	EMS	2	conceived the study|participated in the study design|helped with the drafted the paper with	helped with the drafted the paper with	Wrote the paper	Writing - Original Draft	YES
5080790	27782803	RH	2	performed marconi experiments	performed marconi experiments	Performed the experiments	Investigation	YES
5080790	27782803	VA	2	performed pull-down experiments	performed pull-down experiments	Performed the experiments	Investigation	YES
5080790	27782803	XCD	2	participated in the study design|performed pull-down experiments|performed all other experiments|drafted the paper with	participated in the study design	Conceived and designed the experiments	Methodology	YES
5080790	27782803	XCD	2	participated in the study design|performed pull-down experiments|performed all other experiments|drafted the paper with	performed pull-down experiments	Performed the experiments	Investigation	YES
5080790	27782803	XCD	2	participated in the study design|performed pull-down experiments|performed all other experiments|drafted the paper with	performed all other experiments	Performed the experiments	Investigation	YES
5080790	27782803	XCD	2	participated in the study design|performed pull-down experiments|performed all other experiments|drafted the paper with	drafted the paper with	Wrote the paper	Writing - Original Draft	YES
3852355	24321116	AS	2	were the implementers of this work under	were the implementers of this work under	Performed the experiments	Investigation	YES
3852355	24321116	BB	2	were the implementers of this work under|led the analysis	were the implementers of this work under	Performed the experiments	Investigation	YES
3852355	24321116	BB	2	were the implementers of this work under|led the analysis	led the analysis	-	-	NO
3852355	24321116	EB	2	were the implementers of this work under|led the analysis	were the implementers of this work under	Performed the experiments	Investigation	YES
3852355	24321116	EB	2	were the implementers of this work under|led the analysis	led the analysis	-	-	NO
3852355	24321116	L-GB	2	supervised the were the implementers of this work under|provided ongoing support throughout the process of the entire project	supervised the were the implementers of this work under	Performed the experiments	Investigation|Supervision	YES
3852355	24321116	L-GB	2	supervised the were the implementers of this work under|provided ongoing support throughout the process of the entire project	provided ongoing support throughout the process of the entire project	-	-	NO
3852355	24321116	SB	2	supervised the were the implementers of this work under|provided ongoing support throughout the process of the entire project	supervised the were the implementers of this work under	Performed the experiments	Investigation|Supervision	YES
3852355	24321116	SB	2	supervised the were the implementers of this work under|provided ongoing support throughout the process of the entire project	provided ongoing support throughout the process of the entire project	-	-	NO
1448187	16573838	GJC	PLoS52	designed the experiments|performed the experiments|analyzed the data|wrote, edited, and reviewed the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
1448187	16573838	GJC	PLoS52	designed the experiments|performed the experiments|analyzed the data|wrote, edited, and reviewed the manuscript	performed the experiments	Performed the experiments	Investigation	YES
1448187	16573838	GJC	PLoS52	designed the experiments|performed the experiments|analyzed the data|wrote, edited, and reviewed the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
1448187	16573838	GJC	PLoS52	designed the experiments|performed the experiments|analyzed the data|wrote, edited, and reviewed the manuscript	wrote, edited, and reviewed the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
1448187	16573838	JWS	PLoS52	wrote, edited, and reviewed the manuscript	wrote, edited, and reviewed the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
1448187	16573838	MBP	PLoS52	performed the experiments|analyzed the data|wrote, edited, and reviewed the manuscript	performed the experiments	Performed the experiments	Investigation	YES
1448187	16573838	MBP	PLoS52	performed the experiments|analyzed the data|wrote, edited, and reviewed the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
1448187	16573838	MBP	PLoS52	performed the experiments|analyzed the data|wrote, edited, and reviewed the manuscript	wrote, edited, and reviewed the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
1448187	16573838	NKD	PLoS52	designed the experiments|analyzed the data|wrote, edited, and reviewed the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
1448187	16573838	NKD	PLoS52	designed the experiments|analyzed the data|wrote, edited, and reviewed the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
1448187	16573838	NKD	PLoS52	designed the experiments|analyzed the data|wrote, edited, and reviewed the manuscript	wrote, edited, and reviewed the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
1448187	16573838	NT	PLoS52	analyzed the data|wrote, edited, and reviewed the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
1448187	16573838	NT	PLoS52	analyzed the data|wrote, edited, and reviewed the manuscript	wrote, edited, and reviewed the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
1448187	16573838	SH	PLoS52	designed the experiments|performed the experiments|analyzed the data|wrote, edited, and reviewed the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
1448187	16573838	SH	PLoS52	designed the experiments|performed the experiments|analyzed the data|wrote, edited, and reviewed the manuscript	performed the experiments	Performed the experiments	Investigation	YES
1448187	16573838	SH	PLoS52	designed the experiments|performed the experiments|analyzed the data|wrote, edited, and reviewed the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
1448187	16573838	SH	PLoS52	designed the experiments|performed the experiments|analyzed the data|wrote, edited, and reviewed the manuscript	wrote, edited, and reviewed the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
1448187	16573838	SP	PLoS52	wrote, edited, and reviewed the manuscript	wrote, edited, and reviewed the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
1448187	16573838	SS	PLoS52	designed the experiments|analyzed the data|wrote, edited, and reviewed the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
1448187	16573838	SS	PLoS52	designed the experiments|analyzed the data|wrote, edited, and reviewed the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
1448187	16573838	SS	PLoS52	designed the experiments|analyzed the data|wrote, edited, and reviewed the manuscript	wrote, edited, and reviewed the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
1448187	16573838	WK	PLoS52	performed the experiments|analyzed the data|wrote, edited, and reviewed the manuscript	performed the experiments	Performed the experiments	Investigation	YES
1448187	16573838	WK	PLoS52	performed the experiments|analyzed the data|wrote, edited, and reviewed the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
1448187	16573838	WK	PLoS52	performed the experiments|analyzed the data|wrote, edited, and reviewed the manuscript	wrote, edited, and reviewed the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4400007	25879855	KHC	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400007	25879855	KHC	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400007	25879855	KHK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4400007	25879855	KHK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400007	25879855	KSL	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4400007	25879855	KSL	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4400007	25879855	SCY	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400007	25879855	SCY	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400007	25879855	WKH	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400007	25879855	WKH	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400007	25879855	WKH	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400007	25879855	WKH	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400007	25879855	YEY	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400007	25879855	YEY	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400007	25879855	YEY	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400007	25879855	YEY	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5462956	28642765	CC	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5462956	28642765	CL	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5462956	28642765	CW	PLoS52	designed the project, analyzed the data and wrote the manuscript	designed the project, analyzed the data and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5462956	28642765	HL	PLoS52	performed the experiments, analyzed the data and wrote the manuscript	performed the experiments, analyzed the data and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5462956	28642765	JY	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5462956	28642765	LL	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5462956	28642765	MW	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5462956	28642765	WS	PLoS52	analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5462956	28642765	YW	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5462956	28642765	ZH	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
3854118	24314398	All authors	2	contributed to subsequent drafts and approved the final version	contributed to subsequent drafts and approved the final version	Wrote the paper	Writing - Original Draft	YES
3854118	24314398	Andrew Ball	2	for providing insightful comments to an earlier draft	for providing insightful comments to an earlier draft	Wrote the paper	Writing - Original Draft	YES
3854118	24314398	NF	2	wrote the first draft	wrote the first draft	Wrote the paper	Writing - Original Draft	YES
5080794	27782820	HM	2	participated in genomic analyses	participated in genomic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5080794	27782820	KA	2	participated in genomic analyses	participated in genomic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5080794	27782820	KO	2	participated in genomic analyses	participated in genomic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5080794	27782820	MO	2	participated in genomic analyses|was involved in the final editing	participated in genomic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5080794	27782820	MO	2	participated in genomic analyses|was involved in the final editing	was involved in the final editing	Wrote the paper	Writing - Review & Editing	YES
5080794	27782820	YH	2	wrote the manuscript|participated in genomic analyses	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5080794	27782820	YH	2	wrote the manuscript|participated in genomic analyses	participated in genomic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5080794	27782820	YK	2	performed endoscopic submucosal dissection and tumor biopsies	performed endoscopic submucosal dissection and tumor biopsies	Performed the experiments	Investigation	YES
3854119	24314399	EG	2	critically read and revised subsequest versions	critically read and revised subsequest versions	Wrote the paper	Writing - Review & Editing	YES
3854119	24314399	MTGG	2	critically read and revised subsequest versions	critically read and revised subsequest versions	Wrote the paper	Writing - Review & Editing	YES
3854119	24314399	RKR	2	write originally conceptioalized the view point and was principal author	write originally conceptioalized the view point and was principal author	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4400008	25880849	AAD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400008	25880849	AAD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400008	25880849	AAD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400008	25880849	KVD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400008	25880849	KVD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400008	25880849	KVD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400008	25880849	KVD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400008	25880849	KVD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400008	25880849	WMH	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400008	25880849	WMH	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6416790	30894784	All the authors	2	have given approval to the final version of the manuscript	have given approval to the final version of the manuscript	-	-	NO
5080802	27782799	AP	PLoS52	conceived and designed the experiments|performed the experiments|analysed the data|wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5080802	27782799	AP	PLoS52	conceived and designed the experiments|performed the experiments|analysed the data|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5080802	27782799	AP	PLoS52	conceived and designed the experiments|performed the experiments|analysed the data|wrote the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
5080802	27782799	AP	PLoS52	conceived and designed the experiments|performed the experiments|analysed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5080802	27782799	AV	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5080802	27782799	EB	PLoS52	conceived and designed the experiments|wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5080802	27782799	EB	PLoS52	conceived and designed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5080802	27782799	LS	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5080802	27782799	NM	PLoS52	analysed the data|wrote the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
5080802	27782799	NM	PLoS52	analysed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5080802	27782799	TL	PLoS52	conceived and designed the experiments|wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5080802	27782799	TL	PLoS52	conceived and designed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5080802	27782799	VG	PLoS52	conceived and designed the experiments|wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5080802	27782799	VG	PLoS52	conceived and designed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5080802	27782799	VJ	PLoS52	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5080802	27782799	XM	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
3854120	24314400	IZ	2	has prepared the manuscript and approved its final version	has prepared the manuscript and approved its final version	Wrote the paper	Writing - Original Draft	YES
1468418	16603057	AK	2	made substantial contributions to content of the paper	made substantial contributions to content of the paper	-	-	NO
1468418	16603057	DL	2	made substantial contributions to content of the paper	made substantial contributions to content of the paper	-	-	NO
1468418	16603057	GG	2	made substantial contributions to content of the paper	made substantial contributions to content of the paper	-	-	NO
1468418	16603057	MU	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
1468418	16603057	SL	2	made substantial contributions to content of the paper	made substantial contributions to content of the paper	-	-	NO
1468418	16603057	TW	2	made substantial contributions to content of the paper	made substantial contributions to content of the paper	-	-	NO
1468418	16603057	WV	2	wrote sections of the review	wrote sections of the review	Wrote the paper	Writing - Original Draft	YES
5462957	28642762	All authors	2	reviewed and approved the manuscript	reviewed and approved the manuscript	Wrote the paper	Writing - Review & Editing	YES
5462957	28642762	GA	2	executed some of the experiments and helped in the preparation of the manuscript	executed some of the experiments and helped in the preparation of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5462957	28642762	NS	2	executed some of the experiments and helped in the preparation of the manuscript	executed some of the experiments and helped in the preparation of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5462957	28642762	RK	2	designed the work, analyzed and interpreted the data, wrote the main manuscript	designed the work, analyzed and interpreted the data, wrote the main manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5462957	28642762	SS	2	executed the experiments	executed the experiments	Performed the experiments	Investigation	YES
1468419	16600028	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
1468419	16600028	HAART	2	treatment 0	treatment 0	-	-	NO
5081680	27784279	HJM	2	carried out the rna seq experiments	carried out the rna seq experiments	Performed the experiments	Investigation	YES
5081680	27784279	JCSC	2	carried out the rna seq analyses	carried out the rna seq analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5081680	27784279	MG	2	carried out the rna seq experiments	carried out the rna seq experiments	Performed the experiments	Investigation	YES
5081680	27784279	MLW	2	conceived the project and designed the strategy|carried out all the experiments except rna seq|analyzed the data and wrote the manuscript	conceived the project and designed the strategy	Conceived and designed the experiments	Conceptualization|Methodology	YES
5081680	27784279	MLW	2	conceived the project and designed the strategy|carried out all the experiments except rna seq|analyzed the data and wrote the manuscript	carried out all the experiments except rna seq	Performed the experiments	Investigation	YES
5081680	27784279	MLW	2	conceived the project and designed the strategy|carried out all the experiments except rna seq|analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5081680	27784279	SC	2	carried out the rna seq analyses	carried out the rna seq analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5081680	27784279	SHEK	2	carried out the rna seq experiments	carried out the rna seq experiments	Performed the experiments	Investigation	YES
5081680	27784279	TD	2	conceived the project and designed the strategy|analyzed the data and wrote the manuscript	conceived the project and designed the strategy	Conceived and designed the experiments	Conceptualization|Methodology	YES
5081680	27784279	TD	2	conceived the project and designed the strategy|analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4400009	25879440	ESG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400009	25879440	ESG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400009	25879440	ESG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400009	25879440	ESG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400009	25879440	ESG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400009	25879440	TEM	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400009	25879440	TEM	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3862978	24331754	ADR	PLoS52	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
3862978	24331754	AM	PLoS52	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
3862978	24331754	BVDG	PLoS52	contributed to the acquisition and collection of the data	contributed to the acquisition and collection of the data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
3862978	24331754	CV	PLoS52	designed the study|drafted the manuscript, which was revised and approved by all of the other authors	designed the study	Conceived and designed the experiments	Methodology	YES
3862978	24331754	CV	PLoS52	designed the study|drafted the manuscript, which was revised and approved by all of the other authors	drafted the manuscript, which was revised and approved by all of the other authors	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3862978	24331754	DMV	PLoS52	designed the study|drafted the manuscript, which was revised and approved by all of the other authors	designed the study	Conceived and designed the experiments	Methodology	YES
3862978	24331754	DMV	PLoS52	designed the study|drafted the manuscript, which was revised and approved by all of the other authors	drafted the manuscript, which was revised and approved by all of the other authors	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3862978	24331754	DPV	PLoS52	designed the study|drafted the manuscript, which was revised and approved by all of the other authors	designed the study	Conceived and designed the experiments	Methodology	YES
3862978	24331754	DPV	PLoS52	designed the study|drafted the manuscript, which was revised and approved by all of the other authors	drafted the manuscript, which was revised and approved by all of the other authors	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3862978	24331754	FVW	PLoS52	contributed to the acquisition and collection of the data	contributed to the acquisition and collection of the data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
3862978	24331754	JP	PLoS52	contributed to the acquisition and collection of the data	contributed to the acquisition and collection of the data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
3862978	24331754	SD	PLoS52	designed the study|analyzed the data|drafted the manuscript, which was revised and approved by all of the other authors	designed the study	Conceived and designed the experiments	Methodology	YES
3862978	24331754	SD	PLoS52	designed the study|analyzed the data|drafted the manuscript, which was revised and approved by all of the other authors	analyzed the data	Analyzed the data	Formal analysis	YES
3862978	24331754	SD	PLoS52	designed the study|analyzed the data|drafted the manuscript, which was revised and approved by all of the other authors	drafted the manuscript, which was revised and approved by all of the other authors	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4430652	26064945	Shaohua Wang	2	contributed equally to the preparation of this paper	contributed equally to the preparation of this paper	-	-	NO
4430652	26064945	Wenqing Xia	2	contributed equally to the preparation of this paper	contributed equally to the preparation of this paper	-	-	NO
5462958	28642770	AH	2	analyzed hormone levels in the plant tissues	analyzed hormone levels in the plant tissues	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5462958	28642770	GG	2	designed the study and the experimental set-up	designed the study and the experimental set-up	Conceived and designed the experiments	Methodology	YES
5462958	28642770	KD	2	analyzed hormone levels in the plant tissues	analyzed hormone levels in the plant tissues	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5462958	28642770	KN	2	designed the study and the experimental set-up|executed the experiments	designed the study and the experimental set-up	Conceived and designed the experiments	Methodology	YES
5462958	28642770	KN	2	designed the study and the experimental set-up|executed the experiments	executed the experiments	Performed the experiments	Investigation	YES
5462958	28642770	RV	2	executed the experiments	executed the experiments	Performed the experiments	Investigation	YES
5462958	28642770	TK	2	designed the study and the experimental set-up|executed the experiments|wrote the manuscript, with input from all other authors	designed the study and the experimental set-up	Conceived and designed the experiments	Methodology	YES
5462958	28642770	TK	2	designed the study and the experimental set-up|executed the experiments|wrote the manuscript, with input from all other authors	executed the experiments	Performed the experiments	Investigation	YES
5462958	28642770	TK	2	designed the study and the experimental set-up|executed the experiments|wrote the manuscript, with input from all other authors	wrote the manuscript, with input from all other authors	Wrote the paper	Writing - Original Draft	YES
1475602	16600050	AN	PLoS52	designed the study|drafted the manuscript and approved the final version	designed the study	Conceived and designed the experiments	Methodology	YES
1475602	16600050	AN	PLoS52	designed the study|drafted the manuscript and approved the final version	drafted the manuscript and approved the final version	Wrote the paper	Writing - Original Draft	YES
1475602	16600050	BL	PLoS52	designed the study|analyzed the data|drafted the manuscript and approved the final version	designed the study	Conceived and designed the experiments	Methodology	YES
1475602	16600050	BL	PLoS52	designed the study|analyzed the data|drafted the manuscript and approved the final version	analyzed the data	Analyzed the data	Formal analysis	YES
1475602	16600050	BL	PLoS52	designed the study|analyzed the data|drafted the manuscript and approved the final version	drafted the manuscript and approved the final version	Wrote the paper	Writing - Original Draft	YES
1475602	16600050	DJ	PLoS52	designed the study|recruited and followed the patients|analyzed the data|drafted the manuscript and approved the final version	designed the study	Conceived and designed the experiments	Methodology	YES
1475602	16600050	DJ	PLoS52	designed the study|recruited and followed the patients|analyzed the data|drafted the manuscript and approved the final version	recruited and followed the patients	Performed the experiments	Investigation	YES
1475602	16600050	DJ	PLoS52	designed the study|recruited and followed the patients|analyzed the data|drafted the manuscript and approved the final version	analyzed the data	Analyzed the data	Formal analysis	YES
1475602	16600050	DJ	PLoS52	designed the study|recruited and followed the patients|analyzed the data|drafted the manuscript and approved the final version	drafted the manuscript and approved the final version	Wrote the paper	Writing - Original Draft	YES
5462968	28642776	AK	2	designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
5462968	28642776	KH	2	performed experiments and analyzed data	performed experiments and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5462968	28642776	KK	2	designed the research, performed experiments, analyzed data, and wrote the manuscript	designed the research, performed experiments, analyzed data, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5462968	28642776	KO	2	designed the research, analyzed data, and wrote the manuscript	designed the research, analyzed data, and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5462968	28642776	SI	2	performed experiments and analyzed data	performed experiments and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5462968	28642776	YH	2	designed the research, performed experiments, analyzed data, and wrote the manuscript	designed the research, performed experiments, analyzed data, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5462968	28642776	YM	2	performed experiments and analyzed data	performed experiments and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5081961	27784266	AP	2	carried out the simplified soil microcosm experiments, sample collection and rna extraction	carried out the simplified soil microcosm experiments, sample collection and rna extraction	Performed the experiments	Investigation	YES
5081961	27784266	GP	2	contributed to data interpretation and manuscript writing	contributed to data interpretation and manuscript writing	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5081961	27784266	IP	2	contributed to data interpretation and manuscript writing|conceived the study, designed the experiment and coordinated all research activities	contributed to data interpretation and manuscript writing	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5081961	27784266	IP	2	contributed to data interpretation and manuscript writing|conceived the study, designed the experiment and coordinated all research activities	conceived the study, designed the experiment and coordinated all research activities	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
5081961	27784266	LL	2	carried out the rt-qpcr experiments	carried out the rt-qpcr experiments	Performed the experiments	Investigation	YES
5081961	27784266	LS	2	analysed the rna seq data through mapping, gene expression estimation, annotation and statistical analysis	analysed the rna seq data through mapping, gene expression estimation, annotation and statistical analysis	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5081961	27784266	MP	2	analysed the rna seq data through mapping, gene expression estimation, annotation and statistical analysis|carried out the rt-qpcr experiments|contributed to data interpretation and manuscript writing	analysed the rna seq data through mapping, gene expression estimation, annotation and statistical analysis	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5081961	27784266	MP	2	analysed the rna seq data through mapping, gene expression estimation, annotation and statistical analysis|carried out the rt-qpcr experiments|contributed to data interpretation and manuscript writing	carried out the rt-qpcr experiments	Performed the experiments	Investigation	YES
5081961	27784266	MP	2	analysed the rna seq data through mapping, gene expression estimation, annotation and statistical analysis|carried out the rt-qpcr experiments|contributed to data interpretation and manuscript writing	contributed to data interpretation and manuscript writing	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5081961	27784266	NH	2	carried out the simplified soil microcosm experiments, sample collection and rna extraction	carried out the simplified soil microcosm experiments, sample collection and rna extraction	Performed the experiments	Investigation	YES
5081961	27784266	YVdP	2	analysed the rna seq data through mapping, gene expression estimation, annotation and statistical analysis	analysed the rna seq data through mapping, gene expression estimation, annotation and statistical analysis	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
4400010	25881233	HH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4400010	25881233	JU	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4400010	25881233	KT	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4400010	25881233	KW	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400010	25881233	KW	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400010	25881233	KW	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400010	25881233	MF	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4400010	25881233	RK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4400010	25881233	SN	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4400010	25881233	SN	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4400010	25881233	SO	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400010	25881233	SO	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400010	25881233	TY	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4400010	25881233	YM	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1481599	16725040	DYWL	PLoS52	participated in the design of experiments|participated in the interpretation of the results	participated in the design of experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
1481599	16725040	DYWL	PLoS52	participated in the design of experiments|participated in the interpretation of the results	participated in the interpretation of the results	Analyzed the data	Formal analysis	YES
1481599	16725040	EEP	PLoS52	participated in the design of experiments|participated in the interpretation of the results|prepared the manuscript|performed the experiments	participated in the design of experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
1481599	16725040	EEP	PLoS52	participated in the design of experiments|participated in the interpretation of the results|prepared the manuscript|performed the experiments	participated in the interpretation of the results	Analyzed the data	Formal analysis	YES
1481599	16725040	EEP	PLoS52	participated in the design of experiments|participated in the interpretation of the results|prepared the manuscript|performed the experiments	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
1481599	16725040	EEP	PLoS52	participated in the design of experiments|participated in the interpretation of the results|prepared the manuscript|performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
1481599	16725040	EKY	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
1481599	16725040	ER	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
1481599	16725040	JCV	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
1481599	16725040	MC	PLoS52	participated in the design of experiments|participated in the interpretation of the results|prepared the manuscript	participated in the design of experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
1481599	16725040	MC	PLoS52	participated in the design of experiments|participated in the interpretation of the results|prepared the manuscript	participated in the interpretation of the results	Analyzed the data	Formal analysis	YES
1481599	16725040	MC	PLoS52	participated in the design of experiments|participated in the interpretation of the results|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
1481599	16725040	RC	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
1481599	16725040	WBC	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
1481599	16725040	WL	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
1481599	16725040	XL	PLoS52	participated in the interpretation of the results|performed the experiments	participated in the interpretation of the results	Analyzed the data	Formal analysis	YES
1481599	16725040	XL	PLoS52	participated in the interpretation of the results|performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
1481599	16725040	YL	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
3871830	24369739	A.J.	2	designed the study|supervised and conducted the study|supervised and/or performed the data management and data entry|for submission	designed the study	Conceived and designed the experiments	Methodology	YES
3871830	24369739	A.J.	2	designed the study|supervised and conducted the study|supervised and/or performed the data management and data entry|for submission	supervised and conducted the study	Performed the experiments	Investigation|Supervision	YES
3871830	24369739	A.J.	2	designed the study|supervised and conducted the study|supervised and/or performed the data management and data entry|for submission	supervised and/or performed the data management and data entry	Analyzed the data	Data curation|Supervision	YES
3871830	24369739	A.J.	2	designed the study|supervised and conducted the study|supervised and/or performed the data management and data entry|for submission	for submission	-	-	NO
3871830	24369739	D.K.E.	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
3871830	24369739	E.B.	2	supervised and/or performed the data management and data entry	supervised and/or performed the data management and data entry	Analyzed the data	Data curation|Supervision	YES
3871830	24369739	E.D.	2	supervised and/or performed the data acquisition	supervised and/or performed the data acquisition	Performed the experiments	Investigation|Supervision	YES
3871830	24369739	F.D.	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
3871830	24369739	F.G.	2	supervised and conducted the study|supervised and/or performed the data acquisition|supervised and/or performed the data management and data entry	supervised and conducted the study	Performed the experiments	Investigation|Supervision	YES
3871830	24369739	F.G.	2	supervised and conducted the study|supervised and/or performed the data acquisition|supervised and/or performed the data management and data entry	supervised and/or performed the data acquisition	Performed the experiments	Investigation|Supervision	YES
3871830	24369739	F.G.	2	supervised and conducted the study|supervised and/or performed the data acquisition|supervised and/or performed the data management and data entry	supervised and/or performed the data management and data entry	Analyzed the data	Data curation|Supervision	YES
3871830	24369739	J.C.A.	2	supervised and/or performed the data management and data entry	supervised and/or performed the data management and data entry	Analyzed the data	Data curation|Supervision	YES
3871830	24369739	J.C.K.	2	supervised and/or performed the data acquisition	supervised and/or performed the data acquisition	Performed the experiments	Investigation|Supervision	YES
3871830	24369739	J.D.	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
3871830	24369739	R.B.	2	supervised and/or performed the data acquisition	supervised and/or performed the data acquisition	Performed the experiments	Investigation|Supervision	YES
5462972	28642783	CJ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5462972	28642783	H-SL	PLoS52	contributed reagents/materials/analysis tools	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5462972	28642783	HK	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5462972	28642783	HK	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5462972	28642783	HK	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5462972	28642783	HK	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5462972	28642783	LK	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5462972	28642783	LK	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5462972	28642783	LK	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5462972	28642783	LK	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5462972	28642783	QK	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5462972	28642783	QK	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5462972	28642783	S-CP	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5462972	28642783	S-SK	PLoS52	conceived and designed the experiments|contributed reagents/materials/analysis tools|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5462972	28642783	S-SK	PLoS52	conceived and designed the experiments|contributed reagents/materials/analysis tools|wrote the paper	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5462972	28642783	S-SK	PLoS52	conceived and designed the experiments|contributed reagents/materials/analysis tools|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5462972	28642783	YK	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5084323	27793086	DKS	1	Conceived the project|Wrote the manuscript	Conceived the project	Conceived and designed the experiments	Conceptualization	YES
5084323	27793086	DKS	1	Conceived the project|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5084323	27793086	MRL	1	Conceived the project|Collected specimens and samples|Analyzed sequence data|Wrote the manuscript	Conceived the project	Conceived and designed the experiments	Conceptualization	YES
5084323	27793086	MRL	1	Conceived the project|Collected specimens and samples|Analyzed sequence data|Wrote the manuscript	Collected specimens and samples	Performed the experiments	Investigation	YES
5084323	27793086	MRL	1	Conceived the project|Collected specimens and samples|Analyzed sequence data|Wrote the manuscript	Analyzed sequence data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5084323	27793086	MRL	1	Conceived the project|Collected specimens and samples|Analyzed sequence data|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5084323	27793086	TEZ	1	Conceived the project|Analyzed sequence data|Wrote the manuscript	Conceived the project	Conceived and designed the experiments	Conceptualization	YES
5084323	27793086	TEZ	1	Conceived the project|Analyzed sequence data|Wrote the manuscript	Analyzed sequence data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5084323	27793086	TEZ	1	Conceived the project|Analyzed sequence data|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4430676	26064965	Ji Hee Oh	2	contributed equally to this work	contributed equally to this work	-	-	NO
4430676	26064965	Yun Kyoung Kim	2	contributed equally to this work	contributed equally to this work	-	-	NO
5462977	28642763	all authors	2	agree to be accountable for the content of the work	agree to be accountable for the content of the work	-	-	NO
3871831	24369738	GDM	7	Assisted in designing the review protocol, screened search results, extracted data, rated evidence, and assisted with analysis and interpretation, and writing of the manuscript	Assisted in designing the review protocol, screened search results, extracted data, rated evidence, and assisted with analysis and interpretation, and writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
3871831	24369738	LT	7	Revised manuscript, gave input on statistical analysis and interpretation	Revised manuscript, gave input on statistical analysis and interpretation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
3871831	24369738	MC	7	Contributed in conception and design of review, edited the manuscript and gave input on interpretation	Contributed in conception and design of review, edited the manuscript and gave input on interpretation	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Review & Editing	YES
3871831	24369738	ME	7	Contributed in conception of review, edited the manuscript and gave input on interpretation	Contributed in conception of review, edited the manuscript and gave input on interpretation	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Review & Editing	YES
3871831	24369738	MZ	7	Contributed in conception and design of review, screened search results, data extraction, analysis and interpretation, and writing of the manuscript	Contributed in conception and design of review, screened search results, data extraction, analysis and interpretation, and writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Data curation|Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
3680992	23802030	KB	1	Data collection and analysis|Manuscript preparation	Data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3680992	23802030	KB	1	Data collection and analysis|Manuscript preparation	Manuscript preparation	Wrote the paper	Writing - Original Draft	YES
3680992	23802030	KH	1	Study design|Data collection and analysis|Manuscript preparation	Study design	Conceived and designed the experiments	Methodology	YES
3680992	23802030	KH	1	Study design|Data collection and analysis|Manuscript preparation	Data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3680992	23802030	KH	1	Study design|Data collection and analysis|Manuscript preparation	Manuscript preparation	Wrote the paper	Writing - Original Draft	YES
1481600	16635263	HIV	2	general toxicity studies	general toxicity studies	-	-	NO
4400011	25879758	MHJS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Interpreted the data|Approved the final version of the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400011	25879758	MHJS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Interpreted the data|Approved the final version of the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4400011	25879758	MHJS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Interpreted the data|Approved the final version of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4400011	25879758	MHJS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Interpreted the data|Approved the final version of the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400011	25879758	MHJS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Interpreted the data|Approved the final version of the manuscript	Interpreted the data	Analyzed the data	Formal analysis	YES
4400011	25879758	MHJS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Interpreted the data|Approved the final version of the manuscript	Approved the final version of the manuscript	-	-	NO
4400011	25879758	PF	PLoS5	Conceived and designed the experiments|Interpreted the data|Revised the article critically for important intellectual content|Approved the final version of the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400011	25879758	PF	PLoS5	Conceived and designed the experiments|Interpreted the data|Revised the article critically for important intellectual content|Approved the final version of the manuscript	Interpreted the data	Analyzed the data	Formal analysis	YES
4400011	25879758	PF	PLoS5	Conceived and designed the experiments|Interpreted the data|Revised the article critically for important intellectual content|Approved the final version of the manuscript	Revised the article critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4400011	25879758	PF	PLoS5	Conceived and designed the experiments|Interpreted the data|Revised the article critically for important intellectual content|Approved the final version of the manuscript	Approved the final version of the manuscript	-	-	NO
4400011	25879758	SRD	PLoS5	Conceived and designed the experiments|Interpreted the data|Revised the article critically for important intellectual content|Approved the final version of the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400011	25879758	SRD	PLoS5	Conceived and designed the experiments|Interpreted the data|Revised the article critically for important intellectual content|Approved the final version of the manuscript	Interpreted the data	Analyzed the data	Formal analysis	YES
4400011	25879758	SRD	PLoS5	Conceived and designed the experiments|Interpreted the data|Revised the article critically for important intellectual content|Approved the final version of the manuscript	Revised the article critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4400011	25879758	SRD	PLoS5	Conceived and designed the experiments|Interpreted the data|Revised the article critically for important intellectual content|Approved the final version of the manuscript	Approved the final version of the manuscript	-	-	NO
4400011	25879758	SWS	PLoS5	Conceived and designed the experiments|Wrote the paper|Interpreted the data|Revised the article critically for important intellectual content|Approved the final version of the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400011	25879758	SWS	PLoS5	Conceived and designed the experiments|Wrote the paper|Interpreted the data|Revised the article critically for important intellectual content|Approved the final version of the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400011	25879758	SWS	PLoS5	Conceived and designed the experiments|Wrote the paper|Interpreted the data|Revised the article critically for important intellectual content|Approved the final version of the manuscript	Interpreted the data	Analyzed the data	Formal analysis	YES
4400011	25879758	SWS	PLoS5	Conceived and designed the experiments|Wrote the paper|Interpreted the data|Revised the article critically for important intellectual content|Approved the final version of the manuscript	Revised the article critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4400011	25879758	SWS	PLoS5	Conceived and designed the experiments|Wrote the paper|Interpreted the data|Revised the article critically for important intellectual content|Approved the final version of the manuscript	Approved the final version of the manuscript	-	-	NO
4400011	25879758	TBH	PLoS5	Conceived and designed the experiments|Interpreted the data|Revised the article critically for important intellectual content|Approved the final version of the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400011	25879758	TBH	PLoS5	Conceived and designed the experiments|Interpreted the data|Revised the article critically for important intellectual content|Approved the final version of the manuscript	Interpreted the data	Analyzed the data	Formal analysis	YES
4400011	25879758	TBH	PLoS5	Conceived and designed the experiments|Interpreted the data|Revised the article critically for important intellectual content|Approved the final version of the manuscript	Revised the article critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4400011	25879758	TBH	PLoS5	Conceived and designed the experiments|Interpreted the data|Revised the article critically for important intellectual content|Approved the final version of the manuscript	Approved the final version of the manuscript	-	-	NO
5084355	27793094	KL	PLoS52	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5084355	27793094	NC	PLoS52	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5084355	27793094	RA	PLoS52	analyzed data|wrote the paper	analyzed data	Analyzed the data	Formal analysis	YES
5084355	27793094	RA	PLoS52	analyzed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5084355	27793094	RG	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5084355	27793094	WL	PLoS52	conceived and designed the experiments|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5084355	27793094	WL	PLoS52	conceived and designed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5462980	28642785	Both authors	2	approved the final manuscript	approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5462980	28642785	SS	2	conceived the experiment|designed and conducted the experiment, collected and analyzed the data, and wrote the manuscript	conceived the experiment	Conceived and designed the experiments	Conceptualization	YES
5462980	28642785	SS	2	conceived the experiment|designed and conducted the experiment, collected and analyzed the data, and wrote the manuscript	designed and conducted the experiment, collected and analyzed the data, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5462980	28642785	VR	2	conceived the experiment	conceived the experiment	Conceived and designed the experiments	Conceptualization	YES
3873114	29874325	All authors	2	have read and approved the final manuscript	have read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
3873114	29874325	Literature Review Process	2	and editing	and editing	Wrote the paper	Writing - Review & Editing	YES
4400012	25881083	AAFG	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4400012	25881083	FTRS	PLoS5	The data compilation	The data compilation	-	-	NO
4400012	25881083	MDBC	PLoS5	The data compilation	The data compilation	-	-	NO
4400012	25881083	RAFP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4400012	25881083	RBLS	PLoS5	The data compilation	The data compilation	-	-	NO
4400012	25881083	RCM	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4400012	25881083	RFC	PLoS5	Wrote the paper|The data compilation	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400012	25881083	RFC	PLoS5	Wrote the paper|The data compilation	The data compilation	-	-	NO
4400012	25881083	SCCSM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|The data compilation	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400012	25881083	SCCSM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|The data compilation	Performed the experiments	Performed the experiments	Investigation	YES
4400012	25881083	SCCSM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|The data compilation	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400012	25881083	SCCSM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|The data compilation	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400012	25881083	SCCSM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|The data compilation	The data compilation	-	-	NO
4400012	25881083	SMP	PLoS5	Conceived and designed the experiments|Wrote the paper|The data compilation	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400012	25881083	SMP	PLoS5	Conceived and designed the experiments|Wrote the paper|The data compilation	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400012	25881083	SMP	PLoS5	Conceived and designed the experiments|Wrote the paper|The data compilation	The data compilation	-	-	NO
4400012	25881083	VLDS	PLoS5	The data compilation	The data compilation	-	-	NO
5084403	27793078	CHG	2	contributed with valuable discussions	contributed with valuable discussions	-	-	NO
5084403	27793078	JML	2	performed experiments, analyzed data and wrote the first draft of the manuscript	performed experiments, analyzed data and wrote the first draft of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5084403	27793078	MC	2	provided analytical tools and managed reagents	provided analytical tools and managed reagents	Contributed reagents/materials/analysis tools	Resources	YES
5084403	27793078	PPL	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5084403	27793078	WWL	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5084403	27793078	YZM	2	coordinated the project and contributed with valuable discussions	coordinated the project and contributed with valuable discussions	-	Project administration	YES
5084403	27793078	ZSX	2	coordinated the project, conceived and designed experiments, and edited the manuscript	coordinated the project, conceived and designed experiments, and edited the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Review & Editing	YES
4433627	26064900	Chiara Toniolo	2	was responsible for collection and/or assembly of chemical data, data analysis and interpretation, critical revision of the paper, and final approval of the paper	was responsible for collection and/or assembly of chemical data, data analysis and interpretation, critical revision of the paper, and final approval of the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
4433627	26064900	Marcello Nicoletti	2	carried out collection and/or assembly of chemical data, data analysis and interpretation, writing the paper, critical revision of the paper, and final approval of the paper	carried out collection and/or assembly of chemical data, data analysis and interpretation, writing the paper, critical revision of the paper, and final approval of the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
4433627	26064900	Paola Del Serrone	2	carried out research concept and design, collection and/or assembly of biological assay data, collection and/or assembly of molecular biology assay data, data analysis and interpretation, statistical analysis, writing the paper, critical revision of the paper, and the final approval of the paper	carried out research concept and design, collection and/or assembly of biological assay data, collection and/or assembly of molecular biology assay data, data analysis and interpretation, statistical analysis, writing the paper, critical revision of the paper, and the final approval of the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
3875389	24378223	A.O.	2	were in charge of patient recruitment|were in charge of manuscript elaboration	were in charge of patient recruitment	Performed the experiments	Investigation	YES
3875389	24378223	A.O.	2	were in charge of patient recruitment|were in charge of manuscript elaboration	were in charge of manuscript elaboration	-	-	NO
3875389	24378223	A.R.	2	contributed to the experimental performance	contributed to the experimental performance	Performed the experiments	Investigation	YES
3875389	24378223	All authors	2	significantly contributed to the design and revision of this study and all have read and approved the final version of this manuscript	significantly contributed to the design and revision of this study and all have read and approved the final version of this manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
3875389	24378223	E.R.	2	were deeply involved in data analysis	were deeply involved in data analysis	Analyzed the data	Formal analysis	YES
3875389	24378223	L.H.	2	contributed to the experimental performance	contributed to the experimental performance	Performed the experiments	Investigation	YES
3875389	24378223	L.P-M	2	contributed to the experimental performance	contributed to the experimental performance	Performed the experiments	Investigation	YES
3875389	24378223	P.P-M	2	contributed to the experimental performance|were deeply involved in data analysis	contributed to the experimental performance	Performed the experiments	Investigation	YES
3875389	24378223	P.P-M	2	contributed to the experimental performance|were deeply involved in data analysis	were deeply involved in data analysis	Analyzed the data	Formal analysis	YES
3875389	24378223	S.M.	2	contributed to the experimental performance	contributed to the experimental performance	Performed the experiments	Investigation	YES
5462982	28642775	HL	2	conducted experiments	conducted experiments	Performed the experiments	Investigation	YES
5462982	28642775	KC	2	conducted experiments|drafted the manuscript	conducted experiments	Performed the experiments	Investigation	YES
5462982	28642775	KC	2	conducted experiments|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5462982	28642775	QL	2	critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5462982	28642775	YL	2	conceived and designed the research	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
3361225	22654582	A. Graber	2	guided the design of the study|participated in discussion of the results and coordination to draft the paper	guided the design of the study	Conceived and designed the experiments	Methodology|Supervision	YES
3361225	22654582	A. Graber	2	guided the design of the study|participated in discussion of the results and coordination to draft the paper	participated in discussion of the results and coordination to draft the paper	Wrote the paper	Project administration|Writing - Original Draft	YES
3361225	22654582	C. Baumgartner	2	participated in discussion of the results and coordination to draft the paper	participated in discussion of the results and coordination to draft the paper	Wrote the paper	Project administration|Writing - Original Draft	YES
3361225	22654582	K. Kusonmano	2	carried out the data simulation, established framework for feature selection and classification, analyzed the results, and drafted the paper|participated in discussion of the results and coordination to draft the paper	carried out the data simulation, established framework for feature selection and classification, analyzed the results, and drafted the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3361225	22654582	K. Kusonmano	2	carried out the data simulation, established framework for feature selection and classification, analyzed the results, and drafted the paper|participated in discussion of the results and coordination to draft the paper	participated in discussion of the results and coordination to draft the paper	Wrote the paper	Project administration|Writing - Original Draft	YES
3361225	22654582	K. Liedl	2	participated in discussion of the results and coordination to draft the paper	participated in discussion of the results and coordination to draft the paper	Wrote the paper	Project administration|Writing - Original Draft	YES
3361225	22654582	M. Dehmer	2	participated in discussion of the results and coordination to draft the paper	participated in discussion of the results and coordination to draft the paper	Wrote the paper	Project administration|Writing - Original Draft	YES
3361225	22654582	M. Netzer	2	participated in implementation of the framework for feature selection and classification|participated in discussion of the results and coordination to draft the paper	participated in implementation of the framework for feature selection and classification	Performed the experiments	Investigation	YES
3361225	22654582	M. Netzer	2	participated in implementation of the framework for feature selection and classification|participated in discussion of the results and coordination to draft the paper	participated in discussion of the results and coordination to draft the paper	Wrote the paper	Project administration|Writing - Original Draft	YES
4400014	25881082	AD	PLoS5	Performed the experiments|Analyzed the data|Interpreted the data	Performed the experiments	Performed the experiments	Investigation	YES
4400014	25881082	AD	PLoS5	Performed the experiments|Analyzed the data|Interpreted the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4400014	25881082	AD	PLoS5	Performed the experiments|Analyzed the data|Interpreted the data	Interpreted the data	Analyzed the data	Formal analysis	YES
4400014	25881082	EB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Interpreted the data	Performed the experiments	Performed the experiments	Investigation	YES
4400014	25881082	EB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Interpreted the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4400014	25881082	EB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Interpreted the data	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400014	25881082	EB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Interpreted the data	Interpreted the data	Analyzed the data	Formal analysis	YES
4400014	25881082	LK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Interpreted the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400014	25881082	LK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Interpreted the data	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400014	25881082	LK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Interpreted the data	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400014	25881082	LK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Interpreted the data	Interpreted the data	Analyzed the data	Formal analysis	YES
4400014	25881082	RC	PLoS5	Conceived and designed the experiments|Interpreted the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400014	25881082	RC	PLoS5	Conceived and designed the experiments|Interpreted the data	Interpreted the data	Analyzed the data	Formal analysis	YES
4400014	25881082	ZKM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Interpreted the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400014	25881082	ZKM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Interpreted the data	Performed the experiments	Performed the experiments	Investigation	YES
4400014	25881082	ZKM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Interpreted the data	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400014	25881082	ZKM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Interpreted the data	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400014	25881082	ZKM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Interpreted the data	Interpreted the data	Analyzed the data	Formal analysis	YES
3880941	24388495	All authors	2	have significantly contributed to this study|have seen and approved the final version of the manuscript	have significantly contributed to this study	-	-	NO
3880941	24388495	All authors	2	have significantly contributed to this study|have seen and approved the final version of the manuscript	have seen and approved the final version of the manuscript	-	-	NO
3880941	24388495	AvdV	2	were responsible for the conception and design of this study|wrote the first draft of the manuscript	were responsible for the conception and design of this study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3880941	24388495	AvdV	2	were responsible for the conception and design of this study|wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
3880941	24388495	BA	2	were responsible for the conception and design of this study|collected and assembled the data in indonesia	were responsible for the conception and design of this study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3880941	24388495	BA	2	were responsible for the conception and design of this study|collected and assembled the data in indonesia	collected and assembled the data in indonesia	Performed the experiments	Investigation	YES
3880941	24388495	H. All	2	authors had an opportunity to contribute to the interpretation of the results	authors had an opportunity to contribute to the interpretation of the results	Analyzed the data	Formal analysis	YES
3880941	24388495	HM	2	were responsible for the conception and design of this study|wrote the first draft of the manuscript	were responsible for the conception and design of this study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3880941	24388495	HM	2	were responsible for the conception and design of this study|wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
3880941	24388495	RW	2	collected and assembled the data in indonesia	collected and assembled the data in indonesia	Performed the experiments	Investigation	YES
3880941	24388495	RvC	2	were responsible for the conception and design of this study|wrote the first draft of the manuscript	were responsible for the conception and design of this study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3880941	24388495	RvC	2	were responsible for the conception and design of this study|wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
3880941	24388495	SI	2	collected and assembled the data in indonesia	collected and assembled the data in indonesia	Performed the experiments	Investigation	YES
3880941	24388495	all other authors	2	contributed to further drafts, and all authors approved the final manuscript	contributed to further drafts, and all authors approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5462996	28642769	B-CW	2	conceived and designed this work|wrote the article	conceived and designed this work	Conceived and designed the experiments	Conceptualization	YES
5462996	28642769	B-CW	2	conceived and designed this work|wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
5462996	28642769	FJ	2	performed morphological and anatomic experiments	performed morphological and anatomic experiments	Performed the experiments	Investigation	YES
5462996	28642769	QC	2	provided technical help and suggestions	provided technical help and suggestions	-	-	NO
5462996	28642769	X-MD	2	performed the chip experiment	performed the chip experiment	Performed the experiments	Investigation	YES
5462996	28642769	YL	2	conceived and designed this work|performed the chip experiment|wrote the article	conceived and designed this work	Conceived and designed the experiments	Conceptualization	YES
5462996	28642769	YL	2	conceived and designed this work|performed the chip experiment|wrote the article	performed the chip experiment	Performed the experiments	Investigation	YES
5462996	28642769	YL	2	conceived and designed this work|performed the chip experiment|wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
5462996	28642769	ZS	2	provided technical help and suggestions	provided technical help and suggestions	-	-	NO
4400015	25880317	DW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4400015	25880317	GZ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400015	25880317	JZ	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400015	25880317	JZ	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4400015	25880317	LL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400015	25880317	LL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400015	25880317	LL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400015	25880317	LL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400015	25880317	TL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4400015	25880317	TL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400015	25880317	YC	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5084406	27793082	AS	PLoS52	conceived and designed the experiments|analyzed the data|wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5084406	27793082	AS	PLoS52	conceived and designed the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5084406	27793082	AS	PLoS52	conceived and designed the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5084406	27793082	BJD	PLoS52	conceived and designed the experiments|analyzed the data	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5084406	27793082	BJD	PLoS52	conceived and designed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5084406	27793082	BWD	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5084406	27793082	FGvS	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5084406	27793082	GRM	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5084406	27793082	IH	PLoS52	conceived and designed the experiments|contributed materials	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5084406	27793082	IH	PLoS52	conceived and designed the experiments|contributed materials	contributed materials	Contributed reagents/materials/analysis tools	Resources	YES
5084406	27793082	IJB	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5084406	27793082	IJN	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5084406	27793082	JWMB	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5084406	27793082	LHvdG	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5084406	27793082	MV-L	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5084406	27793082	PAL	PLoS52	conceived and designed the experiments|analyzed the data|wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5084406	27793082	PAL	PLoS52	conceived and designed the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5084406	27793082	PAL	PLoS52	conceived and designed the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5084406	27793082	WB	PLoS52	conceived and designed the experiments|contributed materials	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5084406	27793082	WB	PLoS52	conceived and designed the experiments|contributed materials	contributed materials	Contributed reagents/materials/analysis tools	Resources	YES
1538994	16723028	AP	7	design and statistical analysis	design and statistical analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis	YES
1538994	16723028	DM	7	design, and write-up	design, and write-up	Conceived and designed the experiments|Wrote the paper	-	YES
1538994	16723028	JSGM	7	design, and write-up	design, and write-up	Conceived and designed the experiments|Wrote the paper	-	YES
1538994	16723028	MD	7	design, and write-up	design, and write-up	Conceived and designed the experiments|Wrote the paper	-	YES
1538994	16723028	PK	7	design and write-up	design and write-up	Conceived and designed the experiments|Wrote the paper	-	YES
1538994	16723028	RSH	7	design, data gathering, and write-up	design, data gathering, and write-up	Conceived and designed the experiments|Wrote the paper	-	YES
1538994	16723028	SB	7	design and statistical analysis	design and statistical analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis	YES
1538994	16723028	TK	7	design, and write-up	design, and write-up	Conceived and designed the experiments|Wrote the paper	-	YES
1538994	16723028	VDL	7	design, statistical analysis, write-up	design, statistical analysis, write-up	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis	YES
5463050	28642777	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5463050	28642777	JZ	PLoS52	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5463050	28642777	KT	PLoS52	conceived and designed the project|revised the manuscript	conceived and designed the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5463050	28642777	KT	PLoS52	conceived and designed the project|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5463050	28642777	LL	PLoS52	conceived and designed the project|revised the manuscript	conceived and designed the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5463050	28642777	LL	PLoS52	conceived and designed the project|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5463050	28642777	MC	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5463050	28642777	PS	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5463050	28642777	QS	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5463050	28642777	TY	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5463050	28642777	XF	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5463050	28642777	XH	PLoS52	conceived and designed the project|performed the experiments|analyzed the data|wrote the manuscript	conceived and designed the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5463050	28642777	XH	PLoS52	conceived and designed the project|performed the experiments|analyzed the data|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5463050	28642777	XH	PLoS52	conceived and designed the project|performed the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5463050	28642777	XH	PLoS52	conceived and designed the project|performed the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5463050	28642777	XL	PLoS52	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5463050	28642777	XS	PLoS52	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5463050	28642777	YM	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5463050	28642777	YZ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5463050	28642777	ZL	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5463050	28642777	ZW	PLoS52	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4400016	25879437	ALD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400016	25879437	ALD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400016	25879437	ALD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400016	25879437	ALD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400016	25879437	ALD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400016	25879437	ALK	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4400016	25879437	CLK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400016	25879437	CLK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400016	25879437	CLK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400016	25879437	CLK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400016	25879437	CLK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400016	25879437	DBB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4400016	25879437	DL	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4400016	25879437	PAN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400016	25879437	PAN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400016	25879437	PAN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400016	25879437	PAN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400016	25879437	PAN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400016	25879437	PC	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4400016	25879437	PC	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4400016	25879437	PC	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400016	25879437	ZZ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1553466	16824226	DL	2	participated in subject recruitment, physician evaluations, and helped to draft the manuscript	participated in subject recruitment, physician evaluations, and helped to draft the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
1553466	16824226	JSH	2	conceived of the study, participated in its design and performance, and drafted the manuscript	conceived of the study, participated in its design and performance, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Writing - Original Draft	YES
1553466	16824226	KB	2	participated in questionnaire performance, data collection, and data analysis	participated in questionnaire performance, data collection, and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
1553466	16824226	RS	2	participated in questionnaire performance, data collection, and data analysis	participated in questionnaire performance, data collection, and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
1553466	16824226	SH	2	participated in subject recruitment, physician evaluations, and helped to draft the manuscript	participated in subject recruitment, physician evaluations, and helped to draft the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
1553466	16824226	WCM	2	participated in subject recruitment, physician evaluations, and helped to draft the manuscript	participated in subject recruitment, physician evaluations, and helped to draft the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5463057	28642773	All of the authors	2	participated in the conception and design of the experiments	participated in the conception and design of the experiments	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
5463057	28642773	CB	2	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5463057	28642773	FF	2	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5463057	28642773	FL	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5463057	28642773	GM	2	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5463057	28642773	GS	2	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5463057	28642773	LE	2	performed the experiments and analyzed the data|wrote the manuscript	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5463057	28642773	LE	2	performed the experiments and analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5463057	28642773	MC	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5463057	28642773	SP	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5463057	28642773	all authors	2	interpreted the results and revised the manuscript	interpreted the results and revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
3888902	24433984	All	2	investigators contributed to the concept of this study	investigators contributed to the concept of this study	Conceived and designed the experiments	Conceptualization	YES
3888902	24433984	All other authors	2	critically read and approved the final manuscript	critically read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
3888902	24433984	CPG	2	recruited patients and performed medical interviews|analyzed the data and wrote the paper	recruited patients and performed medical interviews	Performed the experiments	Investigation	YES
3888902	24433984	CPG	2	recruited patients and performed medical interviews|analyzed the data and wrote the paper	analyzed the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3888902	24433984	HJC	2	analyzed the data and wrote the paper	analyzed the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3888902	24433984	NJK	2	recruited patients and performed medical interviews|supervised data analysis and revised the manuscript	recruited patients and performed medical interviews	Performed the experiments	Investigation	YES
3888902	24433984	NJK	2	recruited patients and performed medical interviews|supervised data analysis and revised the manuscript	supervised data analysis and revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Supervision|Writing - Review & Editing	YES
3888902	24433984	OMD	2	recruited patients and performed medical interviews	recruited patients and performed medical interviews	Performed the experiments	Investigation	YES
3888902	24433984	WBP	2	recruited patients and performed medical interviews	recruited patients and performed medical interviews	Performed the experiments	Investigation	YES
5084420	27793085	AAA	2	carried out the de novo assembly, analyzed and interpreted the data, and drafted the manuscript	carried out the de novo assembly, analyzed and interpreted the data, and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5084420	27793085	CJP	2	conceived and designed the study, participated in coordination and contributed to draft manuscript writing and revisions	conceived and designed the study, participated in coordination and contributed to draft manuscript writing and revisions	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft|Writing - Review & Editing	YES
5084420	27793085	DAR	2	participated in analysis and interpretation of data, and critically revised the draft manuscript	participated in analysis and interpretation of data, and critically revised the draft manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5084420	27793085	RNP	2	performed the repetitive element analysis, contributed to writing and editing the manuscript	performed the repetitive element analysis, contributed to writing and editing the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
4400017	25879751	AB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400017	25879751	AB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400017	25879751	AB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400017	25879751	AB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400017	25879751	AMV	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4400017	25879751	LAP	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4400017	25879751	LAP	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400017	25879751	MAP	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4400017	25879751	MAP	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4400017	25879751	MEP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400017	25879751	MEP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400017	25879751	MEP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400017	25879751	MPA	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4400017	25879751	MPA	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400017	25879751	MV	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4400017	25879751	MV	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400021	25880669	KK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400021	25880669	KK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400021	25880669	KK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400021	25880669	KK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400021	25880669	KK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400021	25880669	MW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400021	25880669	MW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400021	25880669	MW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400021	25880669	MW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3889223	24433985	AC	PLoS52	analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
3889223	24433985	AP	PLoS52	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
3889223	24433985	NP	PLoS52	analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
3889223	24433985	PD	PLoS52	analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
3889223	24433985	RM	PLoS52	drafted the manuscript|analysed the data	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
3889223	24433985	RM	PLoS52	drafted the manuscript|analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
3889223	24433985	SC	PLoS52	drafted the manuscript|conceived the study design and critically revised the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
3889223	24433985	SC	PLoS52	drafted the manuscript|conceived the study design and critically revised the manuscript	conceived the study design and critically revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
5084427	27793092	DM	2	participated in the design and coordination and helped to draft the manuscript	participated in the design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Project administration|Writing - Original Draft	YES
5084427	27793092	DR	2	carried out the gene and protein domains functional annotation	carried out the gene and protein domains functional annotation	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5084427	27793092	ERM	2	participated in the study design	participated in the study design	Conceived and designed the experiments	Methodology	YES
5084427	27793092	ES	2	carried out the genome comparative analysis, participated in the study design and drafted the manuscript	carried out the genome comparative analysis, participated in the study design and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5084427	27793092	GT	2	worked at the illumina sequencing data generation and data preprocessing	worked at the illumina sequencing data generation and data preprocessing	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5084427	27793092	RD	2	worked at the illumina sequencing data generation and data preprocessing	worked at the illumina sequencing data generation and data preprocessing	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5084427	27793092	SG	2	worked at the illumina sequencing data generation and data preprocessing	worked at the illumina sequencing data generation and data preprocessing	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5084427	27793092	TH	2	carried out the gene and protein domains functional annotation	carried out the gene and protein domains functional annotation	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5463059	28642779	All authors	PLoS52	discussed the results	discussed the results	-	-	NO
5463059	28642779	LM	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
5463059	28642779	MZ	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
5463059	28642779	PS	PLoS52	designed research|performed research	designed research	Conceived and designed the experiments	Methodology	YES
5463059	28642779	PS	PLoS52	designed research|performed research	performed research	Performed the experiments	Investigation	YES
5463059	28642779	SP	PLoS52	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5463059	28642779	TS	PLoS52	analyzed data|wrote the paper	analyzed data	Analyzed the data	Formal analysis	YES
5463059	28642779	TS	PLoS52	analyzed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5463059	28642779	W-SG	PLoS52	designed research	designed research	Conceived and designed the experiments	Methodology	YES
5463059	28642779	X-LY	PLoS52	designed research|performed research|analyzed data|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
5463059	28642779	X-LY	PLoS52	designed research|performed research|analyzed data|wrote the paper	performed research	Performed the experiments	Investigation	YES
5463059	28642779	X-LY	PLoS52	designed research|performed research|analyzed data|wrote the paper	analyzed data	Analyzed the data	Formal analysis	YES
5463059	28642779	X-LY	PLoS52	designed research|performed research|analyzed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5463059	28642779	Y-QC	PLoS52	designed research|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
5463059	28642779	Y-QC	PLoS52	designed research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
1562434	16859558	DN	2	created and managed the scope study and helped to edit the manuscript	created and managed the scope study and helped to edit the manuscript	Wrote the paper	Project administration|Writing - Review & Editing	YES
1562434	16859558	HM	2	conceived of the study, oversaw its design and coordination, and drafted the manuscript	conceived of the study, oversaw its design and coordination, and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Supervision|Writing - Original Draft	YES
1562434	16859558	JMM	2	created and managed the scope study and helped to edit the manuscript	created and managed the scope study and helped to edit the manuscript	Wrote the paper	Project administration|Writing - Review & Editing	YES
1562434	16859558	JNM	2	created and managed the scope study and helped to edit the manuscript	created and managed the scope study and helped to edit the manuscript	Wrote the paper	Project administration|Writing - Review & Editing	YES
1562434	16859558	LN	2	carried out all sample processing and analysis of data, and helped to draft the mauscript	carried out all sample processing and analysis of data, and helped to draft the mauscript	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Formal analysis|Investigation|Writing - Original Draft	YES
1562434	16859558	PH	2	carried out anova and other statistical analyses	carried out anova and other statistical analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
1562434	16859558	SD	2	created and managed the scope study and helped to edit the manuscript	created and managed the scope study and helped to edit the manuscript	Wrote the paper	Project administration|Writing - Review & Editing	YES
4433632	26064885	A. Robbe	2	contributed equally as first authors	contributed equally as first authors	-	-	NO
4433632	26064885	A. Tassin	2	contributed equally as first authors	contributed equally as first authors	-	-	NO
3895257	24439027	Abou Abdallah Malick	2	contributed with the carried out molecular analysis with the	contributed with the carried out molecular analysis with the	Performed the experiments	Investigation	YES
3895257	24439027	Coumba Toure Kane	2	have conceived and designed the research|drafted the manuscript	have conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
3895257	24439027	Coumba Toure Kane	2	have conceived and designed the research|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
3895257	24439027	Haby Signate Sy	2	are the pediatricians for children care	are the pediatricians for children care	-	-	NO
3895257	24439027	Khady Kebe	2	carried out molecular analysis with the|drafted the manuscript	carried out molecular analysis with the	Performed the experiments	Investigation	YES
3895257	24439027	Khady Kebe	2	carried out molecular analysis with the|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
3895257	24439027	Laurent Belec	2	have conceived and designed the research|drafted the manuscript	have conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
3895257	24439027	Laurent Belec	2	have conceived and designed the research|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
3895257	24439027	Ndeye Rama Diagne	2	are the pediatricians for children care	are the pediatricians for children care	-	-	NO
3895257	24439027	Ngagne Mbaye	2	are the pediatricians for children care	are the pediatricians for children care	-	-	NO
3895257	24439027	Safietou Ngom	2	carried out molecular analysis with the	carried out molecular analysis with the	Performed the experiments	Investigation	YES
3895257	24439027	Sokhna Bousso Gueye	2	contributed with the carried out molecular analysis with the	contributed with the carried out molecular analysis with the	Performed the experiments	Investigation	YES
3895257	24439027	Souleymane Mboup	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4400035	25879852	CKP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400035	25879852	CKP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4400035	25879852	CKP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4400035	25879852	HJJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400035	25879852	HJJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4400035	25879852	HJJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4400035	25879852	HYP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400035	25879852	HYP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400035	25879852	HYP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400035	25879852	HYP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400035	25879852	HYP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400035	25879852	YHK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4400035	25879852	YHK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1592103	16999868	CB	2	participated in its design and coordination and helped to draft the manuscript	participated in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Project administration|Writing - Original Draft	YES
1592103	16999868	EMT	2	carried out the molecular genetic studies	carried out the molecular genetic studies	Performed the experiments	Investigation	YES
1592103	16999868	ET	2	participated in the collection of the blood samples and conception of the study	participated in the collection of the blood samples and conception of the study	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
1592103	16999868	FDT	2	conceived of the study, and participated in its design and coordination	conceived of the study, and participated in its design and coordination	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
1592103	16999868	KDGD	2	participated in the collection of the blood samples and conception of the study	participated in the collection of the blood samples and conception of the study	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
1592103	16999868	MT	2	participated in the design of the study and performed the statistical analysis	participated in the design of the study and performed the statistical analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
1592103	16999868	RC	2	participated in its design and coordination and helped to draft the manuscript	participated in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Project administration|Writing - Original Draft	YES
5463126	28642778	EV	2	performed all the phenotypic evaluation	performed all the phenotypic evaluation	Performed the experiments	Investigation	YES
5463126	28642778	J-LX	2	designed the experiment	designed the experiment	Conceived and designed the experiments	Methodology	YES
5463126	28642778	JD	2	performed all the phenotypic evaluation	performed all the phenotypic evaluation	Performed the experiments	Investigation	YES
5463126	28642778	ML	2	performed analysis and interpretation of the data|drafted the manuscript	performed analysis and interpretation of the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5463126	28642778	ML	2	performed analysis and interpretation of the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5463126	28642778	W-SW	2	performed all the phenotypic evaluation|performed analysis and interpretation of the data|drafted the manuscript	performed all the phenotypic evaluation	Performed the experiments	Investigation	YES
5463126	28642778	W-SW	2	performed all the phenotypic evaluation|performed analysis and interpretation of the data|drafted the manuscript	performed analysis and interpretation of the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5463126	28642778	W-SW	2	performed all the phenotypic evaluation|performed analysis and interpretation of the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5463126	28642778	Y-LP	2	performed all the phenotypic evaluation|drafted the manuscript	performed all the phenotypic evaluation	Performed the experiments	Investigation	YES
5463126	28642778	Y-LP	2	performed all the phenotypic evaluation|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5463126	28642778	Z-KL	2	designed the experiment	designed the experiment	Conceived and designed the experiments	Methodology	YES
5463126	28642778	all authors	2	revised the paper and approved the final version to be published	revised the paper and approved the final version to be published	Wrote the paper	Writing - Review & Editing	YES
5086072	27793091	All authors	2	contributed to preparation of the manuscript	contributed to preparation of the manuscript	Wrote the paper	Writing - Original Draft	YES
5086072	27793091	DA	2	developed cosplicenet and performed all computational analyses	developed cosplicenet and performed all computational analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5086072	27793091	EC	2	designed the study, mined the data, and interpreted the biological findings	designed the study, mined the data, and interpreted the biological findings	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5086072	27793091	RG	2	designed the study, mined the data, and interpreted the biological findings	designed the study, mined the data, and interpreted the biological findings	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
4400037	25879535	ASL	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400037	25879535	ASL	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400037	25879535	EJF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400037	25879535	EJF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400037	25879535	EJF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400037	25879535	EJF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400037	25879535	EJF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400037	25879535	GT	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400037	25879535	GT	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400037	25879535	GT	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400037	25879535	JL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400037	25879535	JL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400037	25879535	JL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400037	25879535	KY	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400037	25879535	KY	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400037	25879535	KY	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400037	25879535	NS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400037	25879535	NS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400037	25879535	NS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400037	25879535	NS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4433633	26064887	Chien-Jung Chen	2	contributed equally to this work	contributed equally to this work	-	-	NO
4433633	26064887	Kang-Chiao Tsai	2	contributed equally to this work	contributed equally to this work	-	-	NO
3895258	24433983	ABS	2	coordinated the fieldwork	coordinated the fieldwork	Performed the experiments	Investigation|Project administration	YES
3895258	24433983	AH	2	contributed to data collection	contributed to data collection	Performed the experiments	Investigation	YES
3895258	24433983	All authors	2	contributed to the interpretation of data, and reviewed and approved the final manuscript	contributed to the interpretation of data, and reviewed and approved the final manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
3895258	24433983	CL	2	designed and coordinated the study and wrote the first draft of the manuscript	designed and coordinated the study and wrote the first draft of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft	YES
3895258	24433983	DS	2	contributed to data collection	contributed to data collection	Performed the experiments	Investigation	YES
3895258	24433983	FK	2	contributed to data collection	contributed to data collection	Performed the experiments	Investigation	YES
3895258	24433983	GB	2	contributed to data collection	contributed to data collection	Performed the experiments	Investigation	YES
3895258	24433983	IS	2	contributed to data collection	contributed to data collection	Performed the experiments	Investigation	YES
3895258	24433983	JRT	2	contributed to data collection	contributed to data collection	Performed the experiments	Investigation	YES
3895258	24433983	PP	2	designed the study, contributed to data collection, did the statistical analysis and wrote the first draft of the manuscript	designed the study, contributed to data collection, did the statistical analysis and wrote the first draft of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
3772566	24044032	AK	1	Study design|Data collection and analysis|Manuscript preparation	Study design	Conceived and designed the experiments	Methodology	YES
3772566	24044032	AK	1	Study design|Data collection and analysis|Manuscript preparation	Data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3772566	24044032	AK	1	Study design|Data collection and analysis|Manuscript preparation	Manuscript preparation	Wrote the paper	Writing - Original Draft	YES
3772566	24044032	IJ	1	Study design|Data collection and analysis|Manuscript preparation	Study design	Conceived and designed the experiments	Methodology	YES
3772566	24044032	IJ	1	Study design|Data collection and analysis|Manuscript preparation	Data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3772566	24044032	IJ	1	Study design|Data collection and analysis|Manuscript preparation	Manuscript preparation	Wrote the paper	Writing - Original Draft	YES
3772566	24044032	KB	1	Study design|Data collection and analysis|Manuscript preparation	Study design	Conceived and designed the experiments	Methodology	YES
3772566	24044032	KB	1	Study design|Data collection and analysis|Manuscript preparation	Data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3772566	24044032	KB	1	Study design|Data collection and analysis|Manuscript preparation	Manuscript preparation	Wrote the paper	Writing - Original Draft	YES
4400038	25880585	JT	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400038	25880585	JT	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400038	25880585	JT	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400038	25880585	JW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400038	25880585	JW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400038	25880585	JW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400038	25880585	JW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400038	25880585	LH	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4400038	25880585	LH	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400038	25880585	LJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400038	25880585	LJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400038	25880585	LJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400038	25880585	LJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400038	25880585	LJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400038	25880585	VB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400038	25880585	VB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400038	25880585	VB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400038	25880585	VB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1609176	16970827	DC	2	assisted in study design and data analysis	assisted in study design and data analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
1609176	16970827	LM	2	conceived of the study, designed the protocol, obtained institutional review board approval, collected and processed samples, performed immunoassays and analyzed the results	conceived of the study, designed the protocol, obtained institutional review board approval, collected and processed samples, performed immunoassays and analyzed the results	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Data curation|Formal analysis|Investigation|Methodology|Project administration	YES
5463179	28642767	BB	2	contribute to writing	contribute to writing	Wrote the paper	-	YES
5463179	28642767	JJR	2	contribute to writing	contribute to writing	Wrote the paper	-	YES
5463179	28642767	JMR	2	contribute to writing	contribute to writing	Wrote the paper	-	YES
5463179	28642767	MC	2	contribute to writing, correction and production of figures	contribute to writing, correction and production of figures	Wrote the paper	Visualization	YES
5463179	28642767	MM-B	2	contribute to writing	contribute to writing	Wrote the paper	-	YES
5088515	27801292	All authors	2	contributed to the manuscripts preparation	contributed to the manuscripts preparation	Wrote the paper	Writing - Original Draft	YES
5088515	27801292	JAM	2	contributed in the conception of the work and software development	contributed in the conception of the work and software development	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceptualization|Software	YES
5088515	27801292	OT	2	supervised the work and provided ideas	supervised the work and provided ideas	Conceived and designed the experiments	Conceptualization|Supervision	YES
3898050	24447595	EW	2	conducted the literature searches and data extraction|wrote the first draft with input from all the authors who then also contributed to, read, and approved the final paper	conducted the literature searches and data extraction	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
3898050	24447595	EW	2	conducted the literature searches and data extraction|wrote the first draft with input from all the authors who then also contributed to, read, and approved the final paper	wrote the first draft with input from all the authors who then also contributed to, read, and approved the final paper	Wrote the paper	Writing - Original Draft	YES
3898050	24447595	GC	2	conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
3898050	24447595	NF	2	conceived the study|conducted the literature searches and data extraction	conceived the study	Conceived and designed the experiments	Conceptualization	YES
3898050	24447595	NF	2	conceived the study|conducted the literature searches and data extraction	conducted the literature searches and data extraction	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
4400039	25879931	BH	CRediT	Contributed reagents/materials/analysis tools|Wrote the paper|Searched the database and screened the relevant papers	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400039	25879931	BH	CRediT	Contributed reagents/materials/analysis tools|Wrote the paper|Searched the database and screened the relevant papers	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400039	25879931	BH	CRediT	Contributed reagents/materials/analysis tools|Wrote the paper|Searched the database and screened the relevant papers	Searched the database and screened the relevant papers	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
4400039	25879931	CWT	CRediT	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Searched the database and screened the relevant papers|supervision	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400039	25879931	CWT	CRediT	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Searched the database and screened the relevant papers|supervision	Performed the experiments	Performed the experiments	Investigation	YES
4400039	25879931	CWT	CRediT	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Searched the database and screened the relevant papers|supervision	Analyzed the data	Analyzed the data	Formal analysis	YES
4400039	25879931	CWT	CRediT	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Searched the database and screened the relevant papers|supervision	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400039	25879931	CWT	CRediT	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Searched the database and screened the relevant papers|supervision	Searched the database and screened the relevant papers	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
4400039	25879931	CWT	CRediT	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Searched the database and screened the relevant papers|supervision	supervision	-	Supervision	YES
4400039	25879931	HW	CRediT	Contributed reagents/materials/analysis tools|Wrote the paper|Searched the database and screened the relevant papers	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400039	25879931	HW	CRediT	Contributed reagents/materials/analysis tools|Wrote the paper|Searched the database and screened the relevant papers	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400039	25879931	HW	CRediT	Contributed reagents/materials/analysis tools|Wrote the paper|Searched the database and screened the relevant papers	Searched the database and screened the relevant papers	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
4400039	25879931	HZ	CRediT	Contributed reagents/materials/analysis tools|Wrote the paper|Searched the database and screened the relevant papers	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400039	25879931	HZ	CRediT	Contributed reagents/materials/analysis tools|Wrote the paper|Searched the database and screened the relevant papers	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400039	25879931	HZ	CRediT	Contributed reagents/materials/analysis tools|Wrote the paper|Searched the database and screened the relevant papers	Searched the database and screened the relevant papers	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
4400039	25879931	KD	CRediT	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Searched the database and screened the relevant papers	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400039	25879931	KD	CRediT	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Searched the database and screened the relevant papers	Performed the experiments	Performed the experiments	Investigation	YES
4400039	25879931	KD	CRediT	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Searched the database and screened the relevant papers	Analyzed the data	Analyzed the data	Formal analysis	YES
4400039	25879931	KD	CRediT	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Searched the database and screened the relevant papers	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400039	25879931	KD	CRediT	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Searched the database and screened the relevant papers	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400039	25879931	KD	CRediT	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Searched the database and screened the relevant papers	Searched the database and screened the relevant papers	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
4400039	25879931	LY	CRediT	Conceived and designed the experiments|Wrote the paper|Searched the database and screened the relevant papers|supervision	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400039	25879931	LY	CRediT	Conceived and designed the experiments|Wrote the paper|Searched the database and screened the relevant papers|supervision	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400039	25879931	LY	CRediT	Conceived and designed the experiments|Wrote the paper|Searched the database and screened the relevant papers|supervision	Searched the database and screened the relevant papers	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
4400039	25879931	LY	CRediT	Conceived and designed the experiments|Wrote the paper|Searched the database and screened the relevant papers|supervision	supervision	-	Supervision	YES
5463184	28642774	All authors	2	listed have made a substantial, direct and intellectual contribution to the work, and approved it for publication	listed have made a substantial, direct and intellectual contribution to the work, and approved it for publication	-	-	NO
5088516	27801294	ACVA	2	analyzed genomic data and wrote the manuscript	analyzed genomic data and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5088516	27801294	ATRV	2	provided bioinformatics resources	provided bioinformatics resources	Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5088516	27801294	All authors	2	gave final approval for publication	gave final approval for publication	-	-	NO
5088516	27801294	DAB	2	designed and coordinated the study, and wrote the manuscript	designed and coordinated the study, and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft	YES
5088516	27801294	FA	2	analyzed genomic data and wrote the manuscript|designed and coordinated the study, and wrote the manuscript	analyzed genomic data and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5088516	27801294	FA	2	analyzed genomic data and wrote the manuscript|designed and coordinated the study, and wrote the manuscript	designed and coordinated the study, and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft	YES
5088516	27801294	JC	2	performed crystallographic characterization and contributed to the manuscript	performed crystallographic characterization and contributed to the manuscript	Performed the experiments	Investigation	YES
5088516	27801294	LCRST	2	contributed data and performed genomic annotation	contributed data and performed genomic annotation	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Formal analysis|Investigation|Resources	YES
5088516	27801294	LGA	2	provided bioinformatics resources	provided bioinformatics resources	Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5088516	27801294	PL	2	contributed data and performed genomic annotation	contributed data and performed genomic annotation	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Formal analysis|Investigation|Resources	YES
5088516	27801294	SL	2	contributed data and performed genomic annotation	contributed data and performed genomic annotation	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Formal analysis|Investigation|Resources	YES
5088516	27801294	UL	2	processed samples, acquired high-speed imaging and electron microscopy data|designed and coordinated the study, and wrote the manuscript	processed samples, acquired high-speed imaging and electron microscopy data	Performed the experiments|Analyzed the data	Data curation|Investigation|Visualization	YES
5088516	27801294	UL	2	processed samples, acquired high-speed imaging and electron microscopy data|designed and coordinated the study, and wrote the manuscript	designed and coordinated the study, and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft	YES
5088516	27801294	VM	2	analyzed genomic data, processed and analyzed microscopy experiments	analyzed genomic data, processed and analyzed microscopy experiments	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
3902178	24461466	AS	2	was the principal investigator, and he coordinated and financially supported the study	was the principal investigator, and he coordinated and financially supported the study	Conceived and designed the experiments	Conceptualization|Funding acquisition|Project administration	YES
3902178	24461466	All authors	2	were involved in the study plan and in reviewing the manuscript	were involved in the study plan and in reviewing the manuscript	Wrote the paper	Writing - Review & Editing	YES
3902178	24461466	BB	2	performed laboratory testing of specimens	performed laboratory testing of specimens	Performed the experiments	Investigation	YES
3902178	24461466	DDC	2	conceived the study, provided the clinical linkage to the study, reviewed the manuscript and provided comments	conceived the study, provided the clinical linkage to the study, reviewed the manuscript and provided comments	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
3902178	24461466	GM	2	contributed to the statistical data analysis, reviewed the manuscript and provided useful comments	contributed to the statistical data analysis, reviewed the manuscript and provided useful comments	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
3902178	24461466	LL	2	conceived the study, provided the clinical linkage to the study, reviewed the manuscript and provided comments	conceived the study, provided the clinical linkage to the study, reviewed the manuscript and provided comments	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
3902178	24461466	ML	2	conceived the study, provided the clinical linkage to the study, reviewed the manuscript and provided comments	conceived the study, provided the clinical linkage to the study, reviewed the manuscript and provided comments	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
3902178	24461466	PN	2	conceived the study, provided the clinical linkage to the study, reviewed the manuscript and provided comments	conceived the study, provided the clinical linkage to the study, reviewed the manuscript and provided comments	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
3902178	24461466	WA	2	conceived the study, provided the clinical linkage to the study, reviewed the manuscript and provided comments	conceived the study, provided the clinical linkage to the study, reviewed the manuscript and provided comments	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
1626477	17044932	AH	7	Designed the study, interpreted and analyzed the data, reviewed the drafted manuscript	Designed the study, interpreted and analyzed the data, reviewed the drafted manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
1626477	17044932	BSP	7	Designed and coordinated the study, interpreted the data, reviewed the drafted manuscript	Designed and coordinated the study, interpreted the data, reviewed the drafted manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Project administration|Writing - Original Draft|Writing - Review & Editing	YES
1626477	17044932	EM	7	Designed the study, participated in data analysis, and reviewed the drafted manuscript	Designed the study, participated in data analysis, and reviewed the drafted manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
1626477	17044932	JU	7	Participated in data collection, laboratory testing and data analysis, also reviewed the drafted manuscript	Participated in data collection, laboratory testing and data analysis, also reviewed the drafted manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
1626477	17044932	NES	7	Designed the study, supervised laboratory testing, reviewed the drafted manuscript	Designed the study, supervised laboratory testing, reviewed the drafted manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
1626477	17044932	SEM	7	Designed the study, coordinated recruitment of patients, collected and entered data, analyzed data and drafted the manuscript	Designed the study, coordinated recruitment of patients, collected and entered data, analyzed data and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Project administration|Writing - Original Draft	YES
4400040	25879219	ACHY	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400040	25879219	ACHY	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400040	25879219	ACHY	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400040	25879219	AHYT	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4400040	25879219	AHYT	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4400040	25879219	GV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400040	25879219	GV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400040	25879219	GV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400040	25879219	GV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400040	25879219	JGC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400040	25879219	JGC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400040	25879219	JGC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400040	25879219	JLT	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4400040	25879219	JLT	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400040	25879219	JW	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4400040	25879219	JW	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400040	25879219	QHC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400040	25879219	QHC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400040	25879219	ZZW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400040	25879219	ZZW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400040	25879219	ZZW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400040	25879219	ZZW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3906483	24476751	ARG	2	contributed to the conception and design of the study, analysis, and interpretation of data|also developed the first draft of the article	contributed to the conception and design of the study, analysis, and interpretation of data	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Methodology|Resources	YES
3906483	24476751	ARG	2	contributed to the conception and design of the study, analysis, and interpretation of data|also developed the first draft of the article	also developed the first draft of the article	Wrote the paper	Writing - Original Draft	YES
3906483	24476751	ARI	2	carried out the lfa test	carried out the lfa test	Performed the experiments	Investigation	YES
3906483	24476751	All authors	2	contributed to data analysis and interpretation	contributed to data analysis and interpretation	Analyzed the data	Formal analysis	YES
3906483	24476751	HM	2	contributed to statistical analysis and interpretation	contributed to statistical analysis and interpretation	Analyzed the data	Formal analysis	YES
3906483	24476751	RW	2	was responsible for the whole hiv cohort and contributed to patient data collection and analysis	was responsible for the whole hiv cohort and contributed to patient data collection and analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
3906483	24476751	RvC	2	contributed to the conception and design of the study, analysis, and interpretation of data|also developed the first draft of the article	contributed to the conception and design of the study, analysis, and interpretation of data	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Methodology|Resources	YES
3906483	24476751	RvC	2	contributed to the conception and design of the study, analysis, and interpretation of data|also developed the first draft of the article	also developed the first draft of the article	Wrote the paper	Writing - Original Draft	YES
5463273	28642780	XY	2	designed and performed experiments, and prepared the figures|wrote the manuscript	designed and performed experiments, and prepared the figures	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Visualization	YES
5463273	28642780	XY	2	designed and performed experiments, and prepared the figures|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5463273	28642780	YH	2	conceived the research, supervised the experiment|wrote the manuscript	conceived the research, supervised the experiment	Conceived and designed the experiments	Conceptualization|Supervision	YES
5463273	28642780	YH	2	conceived the research, supervised the experiment|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5463273	28642780	ZY	2	provided technical assistance	provided technical assistance	Performed the experiments	Investigation	YES
5088517	27801298	DJM	2	critically analyzed data	critically analyzed data	Analyzed the data	Formal analysis	YES
5088517	27801298	GAO	2	handled clone collection and manufactured microarrays	handled clone collection and manufactured microarrays	Performed the experiments	Investigation	YES
5088517	27801298	KFR	2	designed the transformation procedure, performed cell culture and nucleic acids isolation	designed the transformation procedure, performed cell culture and nucleic acids isolation	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5088517	27801298	SA	2	critically analyzed data	critically analyzed data	Analyzed the data	Formal analysis	YES
5088517	27801298	UU	2	conceived the study, performed microarray experiments, analyzed data and wrote the manuscript	conceived the study, performed microarray experiments, analyzed data and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
4400043	25879848	DJ	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4400043	25879848	DJ	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4400043	25879848	HWC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400043	25879848	HWC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400043	25879848	HWC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400043	25879848	LFD	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400043	25879848	LWL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400043	25879848	QW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400043	25879848	QW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400043	25879848	QW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400043	25879848	QW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1634865	17059603	FOA	2	conceived, designed the study and carried out the molecular genetic studies, participated in the sequence alignment and drafted the manuscript	conceived, designed the study and carried out the molecular genetic studies, participated in the sequence alignment and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Writing - Original Draft	YES
1634865	17059603	FS	2	performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
1634865	17059603	KK	2	participated in acquisition of data, sequence alignment, drafted and reviewed the manuscript	participated in acquisition of data, sequence alignment, drafted and reviewed the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
1634865	17059603	VB	2	participated in the design and helped to review the manuscript	participated in the design and helped to review the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Review & Editing	YES
3916671	24499779	All authors	2	participated in the design of the study and manuscript preparation	participated in the design of the study and manuscript preparation	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3916671	24499779	OM	2	performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
5463276	28642781	AU	PLoS52	revised and edited the manuscript and also provided advice on the experiments	revised and edited the manuscript and also provided advice on the experiments	Wrote the paper	Writing - Review & Editing	YES
5463276	28642781	CY	PLoS52	initiated and designed the research|revised and edited the manuscript and also provided advice on the experiments	initiated and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5463276	28642781	CY	PLoS52	initiated and designed the research|revised and edited the manuscript and also provided advice on the experiments	revised and edited the manuscript and also provided advice on the experiments	Wrote the paper	Writing - Review & Editing	YES
5463276	28642781	HA	PLoS52	revised and edited the manuscript and also provided advice on the experiments	revised and edited the manuscript and also provided advice on the experiments	Wrote the paper	Writing - Review & Editing	YES
5463276	28642781	HH	PLoS52	revised and edited the manuscript and also provided advice on the experiments	revised and edited the manuscript and also provided advice on the experiments	Wrote the paper	Writing - Review & Editing	YES
5463276	28642781	MA	PLoS52	revised and edited the manuscript and also provided advice on the experiments	revised and edited the manuscript and also provided advice on the experiments	Wrote the paper	Writing - Review & Editing	YES
5463276	28642781	MI	PLoS52	revised and edited the manuscript and also provided advice on the experiments	revised and edited the manuscript and also provided advice on the experiments	Wrote the paper	Writing - Review & Editing	YES
5463276	28642781	SF	PLoS52	revised and edited the manuscript and also provided advice on the experiments	revised and edited the manuscript and also provided advice on the experiments	Wrote the paper	Writing - Review & Editing	YES
5463276	28642781	SS	PLoS52	initiated and designed the research|performed the experiments	initiated and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5463276	28642781	SS	PLoS52	initiated and designed the research|performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5463276	28642781	WN	PLoS52	revised and edited the manuscript and also provided advice on the experiments	revised and edited the manuscript and also provided advice on the experiments	Wrote the paper	Writing - Review & Editing	YES
4400046	25879774	HMV	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400046	25879774	HMV	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400046	25879774	MFM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400046	25879774	MFM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400046	25879774	MFM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400046	25879774	MFM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400046	25879774	MVP	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400046	25879774	MVP	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400046	25879774	MVP	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400046	25879774	TCT	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400046	25879774	TCT	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400046	25879774	TCT	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400046	25879774	WRW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400046	25879774	WRW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400046	25879774	WRW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400046	25879774	WRW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5088518	27801290	ATRV	7	designed the experiment, supervised the research, revised the manuscript and serve as corresponding authors	designed the experiment, supervised the research, revised the manuscript and serve as corresponding authors	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Review & Editing	YES
5088518	27801290	AZ	7	designed the experiment, supervised the research, revised the manuscript and serve as corresponding authors	designed the experiment, supervised the research, revised the manuscript and serve as corresponding authors	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Review & Editing	YES
5088518	27801290	CPSG	7	in silico analysis and read the manuscript	in silico analysis and read the manuscript	-	Formal analysis	YES
5088518	27801290	FMS	7	designed the experiment, performed the in silico analysis, rt pcr experiments, data analysis, interpreting the results and drafting and writing the manuscript	designed the experiment, performed the in silico analysis, rt pcr experiments, data analysis, interpreting the results and drafting and writing the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5088518	27801290	GLM	7	performed target predictions analysis, read the manuscript	performed target predictions analysis, read the manuscript	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5088518	27801290	GMB	7	performed the rt-pcr experiments, data analysis and read the manuscript	performed the rt-pcr experiments, data analysis and read the manuscript	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5088518	27801290	ISS	7	supervised the research interpreting the results, wrote and corrected the manuscript	supervised the research interpreting the results, wrote and corrected the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
5088518	27801290	LSB	7	performed the rt-pcr experiments, data analysis and read the manuscript	performed the rt-pcr experiments, data analysis and read the manuscript	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5088518	27801290	MFS	7	supervised the work, interpreting the results and corrected the manuscript	supervised the work, interpreting the results and corrected the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Supervision|Writing - Review & Editing	YES
5088518	27801290	SH	7	performed the target predictions analysis and read the manuscript	performed the target predictions analysis and read the manuscript	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5463277	28642782	CX	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5463277	28642782	HW	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5463277	28642782	JH	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5463277	28642782	LW	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5463277	28642782	PL	PLoS52	designed and supervised this study	designed and supervised this study	Conceived and designed the experiments	Methodology|Supervision	YES
5463277	28642782	RS	PLoS52	supervised this study	supervised this study	-	Supervision	YES
5463277	28642782	WS	PLoS52	polished the writing	polished the writing	Wrote the paper	-	YES
1636060	17042936	BK	2	participated in the design of the study and performed the statistical analysis	participated in the design of the study and performed the statistical analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
1636060	17042936	MT	2	conceived of the study, and participated in its design, coordination and drafted the manuscript	conceived of the study, and participated in its design, coordination and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
1636060	17042936	RP	2	participated in design of the study, monitored the progress and reviewed the draft of the manuscript	participated in design of the study, monitored the progress and reviewed the draft of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
1636060	17042936	SM	2	participated in design of the study, monitored the progress and reviewed the draft of the manuscript	participated in design of the study, monitored the progress and reviewed the draft of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
3925800	24560342	Annabelle Nunuz	2	facilitated the literature search	facilitated the literature search	-	Formal analysis	YES
3925800	24560342	Caitlin Marshall	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
3925800	24560342	Echezona Ezeanolue	2	reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
3925800	24560342	Hilary Rees	2	facilitated the literature search	facilitated the literature search	-	Formal analysis	YES
3925800	24560342	John Ehiri	2	collected, analyzed and interpreted the data|drafted the manuscript|reviewed and edited the manuscript	collected, analyzed and interpreted the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3925800	24560342	John Ehiri	2	collected, analyzed and interpreted the data|drafted the manuscript|reviewed and edited the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
3925800	24560342	John Ehiri	2	collected, analyzed and interpreted the data|drafted the manuscript|reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
3925800	24560342	Ying Li	2	facilitated the literature search|collected, analyzed and interpreted the data|drafted the manuscript	facilitated the literature search	-	Formal analysis	YES
3925800	24560342	Ying Li	2	facilitated the literature search|collected, analyzed and interpreted the data|drafted the manuscript	collected, analyzed and interpreted the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3925800	24560342	Ying Li	2	facilitated the literature search|collected, analyzed and interpreted the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4400066	25879933	AM	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400066	25879933	AM	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400066	25879933	AR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400066	25879933	AR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400066	25879933	AR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400066	25879933	AR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400066	25879933	AR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400066	25879933	BW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400066	25879933	BW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400066	25879933	BW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400066	25879933	BW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400066	25879933	FP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400066	25879933	FP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400066	25879933	FP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400066	25879933	FP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400066	25879933	JY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400066	25879933	JY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400066	25879933	JY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400066	25879933	JY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400066	25879933	JY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400066	25879933	KK	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400066	25879933	KK	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400066	25879933	SvdW	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400066	25879933	SvdW	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400066	25879933	SvdW	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3927729	24560340	CAR	PLoS52	performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
3927729	24560340	CMC	PLoS52	designed the cytotoxicity assays and wrote the manuscript|performed the cytotoxicity assays|analyzed the data	designed the cytotoxicity assays and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3927729	24560340	CMC	PLoS52	designed the cytotoxicity assays and wrote the manuscript|performed the cytotoxicity assays|analyzed the data	performed the cytotoxicity assays	Performed the experiments	Investigation	YES
3927729	24560340	CMC	PLoS52	designed the cytotoxicity assays and wrote the manuscript|performed the cytotoxicity assays|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
3927729	24560340	GC	PLoS52	classified the patients and designed the study|performed the elisas|designed the cytotoxicity assays and wrote the manuscript|performed the cytotoxicity assays|analyzed the data|wrote the manuscript, which was reviewed and accepted by all authors	classified the patients and designed the study	Conceived and designed the experiments	Methodology	YES
3927729	24560340	GC	PLoS52	classified the patients and designed the study|performed the elisas|designed the cytotoxicity assays and wrote the manuscript|performed the cytotoxicity assays|analyzed the data|wrote the manuscript, which was reviewed and accepted by all authors	performed the elisas	Performed the experiments	Investigation	YES
3927729	24560340	GC	PLoS52	classified the patients and designed the study|performed the elisas|designed the cytotoxicity assays and wrote the manuscript|performed the cytotoxicity assays|analyzed the data|wrote the manuscript, which was reviewed and accepted by all authors	designed the cytotoxicity assays and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3927729	24560340	GC	PLoS52	classified the patients and designed the study|performed the elisas|designed the cytotoxicity assays and wrote the manuscript|performed the cytotoxicity assays|analyzed the data|wrote the manuscript, which was reviewed and accepted by all authors	performed the cytotoxicity assays	Performed the experiments	Investigation	YES
3927729	24560340	GC	PLoS52	classified the patients and designed the study|performed the elisas|designed the cytotoxicity assays and wrote the manuscript|performed the cytotoxicity assays|analyzed the data|wrote the manuscript, which was reviewed and accepted by all authors	analyzed the data	Analyzed the data	Formal analysis	YES
3927729	24560340	GC	PLoS52	classified the patients and designed the study|performed the elisas|designed the cytotoxicity assays and wrote the manuscript|performed the cytotoxicity assays|analyzed the data|wrote the manuscript, which was reviewed and accepted by all authors	wrote the manuscript, which was reviewed and accepted by all authors	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3927729	24560340	LS	PLoS52	classified the patients and designed the study	classified the patients and designed the study	Conceived and designed the experiments	Methodology	YES
3927729	24560340	SAM	PLoS52	performed the elisas|designed the cytotoxicity assays and wrote the manuscript|analyzed the data	performed the elisas	Performed the experiments	Investigation	YES
3927729	24560340	SAM	PLoS52	performed the elisas|designed the cytotoxicity assays and wrote the manuscript|analyzed the data	designed the cytotoxicity assays and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3927729	24560340	SAM	PLoS52	performed the elisas|designed the cytotoxicity assays and wrote the manuscript|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5088519	27801296	P. All	2	authors approve of the final version of this manuscript	authors approve of the final version of this manuscript	-	-	NO
4433640	26064938	Zaoxian Mei	2	contributed equally to this work	contributed equally to this work	-	-	NO
4433640	26064938	Zhaogang Sun	2	contributed equally to this work	contributed equally to this work	-	-	NO
1687192	17132170	BT	2	helped with laboratory and animal experiments and data analysis	helped with laboratory and animal experiments and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
1687192	17132170	CCT	2	was responsible for the overall experimental design, data interpretation and implementation of the project	was responsible for the overall experimental design, data interpretation and implementation of the project	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
1687192	17132170	GB	2	assisted with animal experiments	assisted with animal experiments	Performed the experiments	Investigation	YES
1687192	17132170	MA	2	helped with experimental design and data interpretation	helped with experimental design and data interpretation	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
1687192	17132170	PE	2	carried out the experiments, performed data analysis and wrote the initial drafts of the manuscript	carried out the experiments, performed data analysis and wrote the initial drafts of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
1687192	17132170	YJ	2	helped with laboratory experiments and data interpretation	helped with laboratory experiments and data interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5463297	28642772	AJ	PLoS52	performed the gwas mapping analyses and helped ms analyze the results	performed the gwas mapping analyses and helped ms analyze the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5463297	28642772	AW	PLoS52	performed most of the phenotyping trials	performed most of the phenotyping trials	Performed the experiments	Investigation	YES
5463297	28642772	All authors	PLoS52	contributed to improving the manuscript	contributed to improving the manuscript	Wrote the paper	Writing - Review & Editing	YES
5463297	28642772	CC	PLoS52	suggested experiments and provided resources	suggested experiments and provided resources	Contributed reagents/materials/analysis tools	Resources	YES
5463297	28642772	DB	PLoS52	performed statistical analyses	performed statistical analyses	Analyzed the data	Formal analysis	YES
5463297	28642772	GE	PLoS52	wrote the paper|helped interpret the data	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5463297	28642772	GE	PLoS52	wrote the paper|helped interpret the data	helped interpret the data	Analyzed the data	Formal analysis	YES
5463297	28642772	MS	PLoS52	conceived the study|wrote the paper|performed most of the phenotyping trials	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5463297	28642772	MS	PLoS52	conceived the study|wrote the paper|performed most of the phenotyping trials	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5463297	28642772	MS	PLoS52	conceived the study|wrote the paper|performed most of the phenotyping trials	performed most of the phenotyping trials	Performed the experiments	Investigation	YES
5463297	28642772	NS	PLoS52	performed most of the phenotyping trials	performed most of the phenotyping trials	Performed the experiments	Investigation	YES
5463297	28642772	YS	PLoS52	helped interpret the data	helped interpret the data	Analyzed the data	Formal analysis	YES
3929068	24560341	AM	2	designed the study|wrote the first draft of the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
3929068	24560341	AM	2	designed the study|wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
3929068	24560341	All authors	2	had full access to the data and contributed to and have approved the final manuscript	had full access to the data and contributed to and have approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
3929068	24560341	LAM	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
3929068	24560341	TA	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
4400067	25879752	CNN	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400067	25879752	CNN	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400067	25879752	CNN	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400067	25879752	RYW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400067	25879752	RYW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400067	25879752	RYW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400067	25879752	RYW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400067	25879752	RYW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5088520	27801297	CD	2	developed and documented the r package including the integration of all the databases and resources that this tool uses|also carried out the data collection for several analyses, trials and comparisons using the package|also helped to write the manuscript	developed and documented the r package including the integration of all the databases and resources that this tool uses	Contributed reagents/materials/analysis tools	Resources|Software	YES
5088520	27801297	CD	2	developed and documented the r package including the integration of all the databases and resources that this tool uses|also carried out the data collection for several analyses, trials and comparisons using the package|also helped to write the manuscript	also carried out the data collection for several analyses, trials and comparisons using the package	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5088520	27801297	CD	2	developed and documented the r package including the integration of all the databases and resources that this tool uses|also carried out the data collection for several analyses, trials and comparisons using the package|also helped to write the manuscript	also helped to write the manuscript	Wrote the paper	Writing - Original Draft	YES
5088520	27801297	JDLR	2	designed the study, coordinated the trials along the software developed, supervised the data analysis and wrote the manuscript	designed the study, coordinated the trials along the software developed, supervised the data analysis and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Project administration|Software|Supervision|Writing - Original Draft	YES
5463364	28642766	All authors	2	contributed to write the manuscript	contributed to write the manuscript	Wrote the paper	Writing - Original Draft	YES
5463364	28642766	BB	2	supervised all facets of the project	supervised all facets of the project	-	Supervision	YES
5463364	28642766	DT	2	performed the experiments, and analyzed data	performed the experiments, and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5463364	28642766	LG	2	created compound library, designed and performed the validation step	created compound library, designed and performed the validation step	Conceived and designed the experiments|Performed the experiments	Investigation|Validation	YES
5463364	28642766	LS	2	designed the research and interpreted data	designed the research and interpreted data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5463364	28642766	PK	2	performed the experiments, and analyzed data	performed the experiments, and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5463364	28642766	PM	2	invented the method, designed the research and analyzed data	invented the method, designed the research and analyzed data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Methodology	YES
3929991	24560338	All authors	2	have read and approved the final manuscript|made substantial contributions to concept and design, analysis and interpretation of data, were involved in drafting and revising the manuscript and gave final approval	have read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
3929991	24560338	All authors	2	have read and approved the final manuscript|made substantial contributions to concept and design, analysis and interpretation of data, were involved in drafting and revising the manuscript and gave final approval	made substantial contributions to concept and design, analysis and interpretation of data, were involved in drafting and revising the manuscript and gave final approval	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Resources|Writing - Original Draft|Writing - Review & Editing	YES
4400068	25880426	BGL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400068	25880426	BGL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400068	25880426	BGL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400068	25880426	DSR	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400068	25880426	DSR	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400068	25880426	DSR	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400068	25880426	JS	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400068	25880426	JS	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400068	25880426	KJK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400068	25880426	KJK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400068	25880426	KJK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400068	25880426	KJK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400068	25880426	SAN	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400068	25880426	SAN	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400068	25880426	SCW	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400068	25880426	SCW	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4433642	26064906	Alexa A. Yrineo	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
4433642	26064906	Evan H. Phillips	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
5465253	28649258	All authors	2	listed, have made substantial, direct and intellectual contribution to the work, and approved it for publication	listed, have made substantial, direct and intellectual contribution to the work, and approved it for publication	-	-	NO
4168648	25246997	AK	1	Study design|Manuscript preparation	Study design	Conceived and designed the experiments	Methodology	YES
4168648	25246997	AK	1	Study design|Manuscript preparation	Manuscript preparation	Wrote the paper	Writing - Original Draft	YES
4168648	25246997	CF	1	Manuscript preparation	Manuscript preparation	Wrote the paper	Writing - Original Draft	YES
4168648	25246997	CW	1	Manuscript preparation	Manuscript preparation	Wrote the paper	Writing - Original Draft	YES
4168648	25246997	IJ	1	Study design|Manuscript preparation	Study design	Conceived and designed the experiments	Methodology	YES
4168648	25246997	IJ	1	Study design|Manuscript preparation	Manuscript preparation	Wrote the paper	Writing - Original Draft	YES
4168648	25246997	KB	1	Study design|Manuscript preparation	Study design	Conceived and designed the experiments	Methodology	YES
4168648	25246997	KB	1	Study design|Manuscript preparation	Manuscript preparation	Wrote the paper	Writing - Original Draft	YES
5088521	27801293	ACG	2	conceived and coordinated the project|supervised experimental procedures	conceived and coordinated the project	Conceived and designed the experiments	Conceptualization|Project administration	YES
5088521	27801293	ACG	2	conceived and coordinated the project|supervised experimental procedures	supervised experimental procedures	Performed the experiments	Investigation|Supervision	YES
5088521	27801293	ATRV	2	supervised the sequencing experiments	supervised the sequencing experiments	Performed the experiments	Investigation|Supervision	YES
5088521	27801293	EF	2	performed data analysis and wrote bioinformatics scripts	performed data analysis and wrote bioinformatics scripts	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Software|Writing - Original Draft	YES
5088521	27801293	GB	2	carried out experimental procedures	carried out experimental procedures	Performed the experiments	Investigation	YES
5088521	27801293	GLS	2	performed data analysis and wrote bioinformatics scripts	performed data analysis and wrote bioinformatics scripts	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Software|Writing - Original Draft	YES
5088521	27801293	GRQS	2	performed data analysis and wrote bioinformatics scripts	performed data analysis and wrote bioinformatics scripts	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Software|Writing - Original Draft	YES
5088521	27801293	MFN	2	conceived and coordinated the project|drafted the paper with input from the other authors	conceived and coordinated the project	Conceived and designed the experiments	Conceptualization|Project administration	YES
5088521	27801293	MFN	2	conceived and coordinated the project|drafted the paper with input from the other authors	drafted the paper with input from the other authors	Wrote the paper	Writing - Original Draft	YES
5088521	27801293	MGFC	2	performed data analysis and wrote bioinformatics scripts	performed data analysis and wrote bioinformatics scripts	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Software|Writing - Original Draft	YES
5088521	27801293	PIPR	2	performed data analysis and wrote bioinformatics scripts|drafted the paper with input from the other authors	performed data analysis and wrote bioinformatics scripts	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Software|Writing - Original Draft	YES
5088521	27801293	PIPR	2	performed data analysis and wrote bioinformatics scripts|drafted the paper with input from the other authors	drafted the paper with input from the other authors	Wrote the paper	Writing - Original Draft	YES
5088521	27801293	RG	2	carried out experimental procedures	carried out experimental procedures	Performed the experiments	Investigation	YES
5088521	27801293	TC	2	performed data analysis and wrote bioinformatics scripts	performed data analysis and wrote bioinformatics scripts	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Software|Writing - Original Draft	YES
5088521	27801293	WMBSM	2	carried out experimental procedures	carried out experimental procedures	Performed the experiments	Investigation	YES
6328706	30648160	D. Yeatts	2	contributed to multiple revisions of the article	contributed to multiple revisions of the article	Wrote the paper	Writing - Review & Editing	YES
6328706	30648160	G. Seckin	2	planned the study, performed the data analysis, and wrote the article	planned the study, performed the data analysis, and wrote the article	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
6328706	30648160	S. Hughes	2	contributed to multiple revisions of the article	contributed to multiple revisions of the article	Wrote the paper	Writing - Review & Editing	YES
6328706	30648160	T. Degreve	2	contributed to multiple revisions of the article	contributed to multiple revisions of the article	Wrote the paper	Writing - Review & Editing	YES
3935448	24560339	All authors	2	contributed to the conduct of the study, the interpretation of the results and the writing of the article	contributed to the conduct of the study, the interpretation of the results and the writing of the article	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3935448	24560339	HC	2	managed the dhs databases, conducted the bulk of the statistical and mathematical modelling analyses, and wrote the first draft of the paper	managed the dhs databases, conducted the bulk of the statistical and mathematical modelling analyses, and wrote the first draft of the paper	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Data curation|Formal analysis|Investigation|Methodology|Software|Writing - Original Draft	YES
3935448	24560339	JDS	2	conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
3935448	24560339	LJA-R	2	conceived the study|led the design of the study, mathematical modelling analyses and drafting of the article	conceived the study	Conceived and designed the experiments	Conceptualization	YES
3935448	24560339	LJA-R	2	conceived the study|led the design of the study, mathematical modelling analyses and drafting of the article	led the design of the study, mathematical modelling analyses and drafting of the article	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3935448	24560339	SFA	2	contributed to the mathematical modelling analyses	contributed to the mathematical modelling analyses	Performed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5465258	28649261	AD	2	did the field measurements and sample collection	did the field measurements and sample collection	Performed the experiments	Investigation	YES
5465258	28649261	All	2	auhors discussed the results and contributed to the manuscript writing	auhors discussed the results and contributed to the manuscript writing	Wrote the paper	Writing - Original Draft	YES
5465258	28649261	DO	2	designed the experiment	designed the experiment	Conceived and designed the experiments	Methodology	YES
5465258	28649261	SL	2	designed the experiment	designed the experiment	Conceived and designed the experiments	Methodology	YES
5465258	28649261	UR	2	designed the experiment|did the field measurements and sample collection|performed the leaf carbohydrates and nitrogen analysis and analyzed the data	designed the experiment	Conceived and designed the experiments	Methodology	YES
5465258	28649261	UR	2	designed the experiment|did the field measurements and sample collection|performed the leaf carbohydrates and nitrogen analysis and analyzed the data	did the field measurements and sample collection	Performed the experiments	Investigation	YES
5465258	28649261	UR	2	designed the experiment|did the field measurements and sample collection|performed the leaf carbohydrates and nitrogen analysis and analyzed the data	performed the leaf carbohydrates and nitrogen analysis and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5088522	27801289	FJCL	2	helped in the rna seq data analysis and in the coexpression study	helped in the rna seq data analysis and in the coexpression study	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5088522	27801289	JDLR	2	designed the study|supervised the data analysis, coordinated the study and corrected the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5088522	27801289	JDLR	2	designed the study|supervised the data analysis, coordinated the study and corrected the manuscript	supervised the data analysis, coordinated the study and corrected the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Project administration|Supervision|Writing - Review & Editing	YES
5088522	27801289	JMO	2	participated in the coordination of the study and helped to draft the manuscript	participated in the coordination of the study and helped to draft the manuscript	Wrote the paper	Project administration|Writing - Original Draft	YES
5088522	27801289	KPL	2	carried out the data collection, the databases construction and the computational analyses and comparisons|also helped to write the manuscript|designed the study	carried out the data collection, the databases construction and the computational analyses and comparisons	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Software	YES
5088522	27801289	KPL	2	carried out the data collection, the databases construction and the computational analyses and comparisons|also helped to write the manuscript|designed the study	also helped to write the manuscript	Wrote the paper	Writing - Original Draft	YES
5088522	27801289	KPL	2	carried out the data collection, the databases construction and the computational analyses and comparisons|also helped to write the manuscript|designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5088522	27801289	RAV	2	helped in the reconstruction of the human gene time-scale	helped in the reconstruction of the human gene time-scale	Performed the experiments	Investigation	YES
4400069	25880552	DM	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400069	25880552	EG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400069	25880552	EG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400069	25880552	EG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400069	25880552	GR	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4400069	25880552	GV	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400069	25880552	GV	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400069	25880552	KB	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4400069	25880552	KB	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4400069	25880552	LS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4400069	25880552	MP	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400069	25880552	PM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4400069	25880552	PP	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400069	25880552	RM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4400069	25880552	SF	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4400069	25880552	SF	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4400069	25880552	VDG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1802955	17280617	AAW	2	conceived, designed and implemented the primary study, upon which this secondary resistance study was based	conceived, designed and implemented the primary study, upon which this secondary resistance study was based	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
1802955	17280617	All	2	authors provided review comments and textual modifications during manuscript development	authors provided review comments and textual modifications during manuscript development	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
1802955	17280617	CH	2	performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
1802955	17280617	KES	2	conceived, designed and implemented the primary study, upon which this secondary resistance study was based|authors provided review comments and textual modifications during manuscript development	conceived, designed and implemented the primary study, upon which this secondary resistance study was based	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
1802955	17280617	KES	2	conceived, designed and implemented the primary study, upon which this secondary resistance study was based|authors provided review comments and textual modifications during manuscript development	authors provided review comments and textual modifications during manuscript development	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
1802955	17280617	KM	2	conceived, designed and implemented the primary study, upon which this secondary resistance study was based	conceived, designed and implemented the primary study, upon which this secondary resistance study was based	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
1802955	17280617	LMF	2	conceived, designed and implemented the primary study, upon which this secondary resistance study was based	conceived, designed and implemented the primary study, upon which this secondary resistance study was based	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
1802955	17280617	RY	2	conceived, designed and implemented the primary study, upon which this secondary resistance study was based	conceived, designed and implemented the primary study, upon which this secondary resistance study was based	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
1802955	17280617	SAN	2	conceived, designed and implemented the primary study, upon which this secondary resistance study was based	conceived, designed and implemented the primary study, upon which this secondary resistance study was based	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
1802955	17280617	SIP	2	conceived, designed and implemented the primary study, upon which this secondary resistance study was based	conceived, designed and implemented the primary study, upon which this secondary resistance study was based	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
3936108	24572053	APC	2	jointly planned the search strategy, conducted the literature searches and wrote the manuscript	jointly planned the search strategy, conducted the literature searches and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
3936108	24572053	DPW	2	jointly planned the search strategy and the reporting method, edited the manuscript and initiated and led the review	jointly planned the search strategy and the reporting method, edited the manuscript and initiated and led the review	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
3936108	24572053	DW	2	jointly planned the reporting method and contributed to the discussion	jointly planned the reporting method and contributed to the discussion	Conceived and designed the experiments|Performed the experiments	Conceptualization	YES
3936108	24572053	HHT	2	jointly planned the search strategy and the reporting method, conducted the literature searches, chose the method for processing the cost-effectiveness results for comparison and edited the manuscript	jointly planned the search strategy and the reporting method, conducted the literature searches, chose the method for processing the cost-effectiveness results for comparison and edited the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Review & Editing	YES
3936108	24572053	KH	2	jointly planned the reporting method and contributed to the discussion and edited the manuscript	jointly planned the reporting method and contributed to the discussion and edited the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
3936108	24572053	LZ	2	jointly planned the search strategy and the reporting method	jointly planned the search strategy and the reporting method	Conceived and designed the experiments|Performed the experiments	Conceptualization	YES
3936108	24572053	MG	2	jointly planned the reporting method and contributed to the discussion and edited the manuscript	jointly planned the reporting method and contributed to the discussion and edited the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
3936108	24572053	RTG	2	led the collation and interpretation of the spending data for the case-study countries and edited the manuscript	led the collation and interpretation of the spending data for the case-study countries and edited the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5465259	28649253	All authors	2	contributed to manuscript preparation|have read and approved the final manuscript	contributed to manuscript preparation	Wrote the paper	Writing - Original Draft	YES
5465259	28649253	All authors	2	contributed to manuscript preparation|have read and approved the final manuscript	have read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4400076	25881016	CL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400076	25881016	LX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400076	25881016	LX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400076	25881016	LX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400076	25881016	LX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400076	25881016	LX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400076	25881016	QF	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400076	25881016	SG	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4400076	25881016	SXX	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400076	25881016	SXX	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400076	25881016	SXX	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4433644	26064958	Guanghui Zhu	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
4433644	26064958	Yuan He	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
1808059	17316455	MG	2	contributed to the patient care, data interpretation, and writing of the paper	contributed to the patient care, data interpretation, and writing of the paper	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft	YES
1808059	17316455	VF	2	contributed to the patient care, data interpretation, and writing of the paper	contributed to the patient care, data interpretation, and writing of the paper	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft	YES
4400079	25879662	CW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400079	25879662	CW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400079	25879662	CW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400079	25879662	CW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400079	25879662	CW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400079	25879662	QZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400079	25879662	QZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400079	25879662	QZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400079	25879662	QZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5088523	27801295	AJ	PLoS5	Wrote the article	Wrote the article	Wrote the paper	Writing - Original Draft	YES
5088523	27801295	AS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the article	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5088523	27801295	AS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the article	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5088523	27801295	AS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the article	Wrote the article	Wrote the paper	Writing - Original Draft	YES
5088523	27801295	ATRV	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5088523	27801295	ATRV	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5088523	27801295	FCA	PLoS5	Phylogenetic analyses|Wrote the article	Phylogenetic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5088523	27801295	FCA	PLoS5	Phylogenetic analyses|Wrote the article	Wrote the article	Wrote the paper	Writing - Original Draft	YES
5088523	27801295	GLM	PLoS5	Transcriptome analysis	Transcriptome analysis	-	-	NO
5088523	27801295	MHV	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the article	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5088523	27801295	MHV	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the article	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5088523	27801295	MHV	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the article	Wrote the article	Wrote the paper	Writing - Original Draft	YES
5088523	27801295	NS	PLoS5	Conceived and designed the experiments|Transcriptome analysis|Phylogenetic analyses|Wrote the article	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5088523	27801295	NS	PLoS5	Conceived and designed the experiments|Transcriptome analysis|Phylogenetic analyses|Wrote the article	Transcriptome analysis	-	-	NO
5088523	27801295	NS	PLoS5	Conceived and designed the experiments|Transcriptome analysis|Phylogenetic analyses|Wrote the article	Phylogenetic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5088523	27801295	NS	PLoS5	Conceived and designed the experiments|Transcriptome analysis|Phylogenetic analyses|Wrote the article	Wrote the article	Wrote the paper	Writing - Original Draft	YES
5088523	27801295	RLMG	PLoS5	Conceived and designed the experiments|Transcriptome analysis|Wrote the article	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5088523	27801295	RLMG	PLoS5	Conceived and designed the experiments|Transcriptome analysis|Wrote the article	Transcriptome analysis	-	-	NO
5088523	27801295	RLMG	PLoS5	Conceived and designed the experiments|Transcriptome analysis|Wrote the article	Wrote the article	Wrote the paper	Writing - Original Draft	YES
3942566	24594114	AB	2	performed the statistical analysis|interpreted the analysis and drafted the manuscript	performed the statistical analysis	Analyzed the data	Formal analysis	YES
3942566	24594114	AB	2	performed the statistical analysis|interpreted the analysis and drafted the manuscript	interpreted the analysis and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3942566	24594114	All authors	2	contributed to the conception and design of the study|revised the manuscript critically for intellectual content and have approved the submitted version for publication	contributed to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3942566	24594114	All authors	2	contributed to the conception and design of the study|revised the manuscript critically for intellectual content and have approved the submitted version for publication	revised the manuscript critically for intellectual content and have approved the submitted version for publication	Wrote the paper	Writing - Review & Editing	YES
3942566	24594114	IS	2	contributed to acquisition of data	contributed to acquisition of data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
3942566	24594114	LL	2	contributed to acquisition of data|interpreted the analysis and drafted the manuscript	contributed to acquisition of data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
3942566	24594114	LL	2	contributed to acquisition of data|interpreted the analysis and drafted the manuscript	interpreted the analysis and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3942566	24594114	MF	2	interpreted the analysis and drafted the manuscript	interpreted the analysis and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3942566	24594114	MM	2	contributed to acquisition of data|interpreted the analysis and drafted the manuscript	contributed to acquisition of data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
3942566	24594114	MM	2	contributed to acquisition of data|interpreted the analysis and drafted the manuscript	interpreted the analysis and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3942566	24594114	ST	2	contributed to acquisition of data|performed the statistical analysis|interpreted the analysis and drafted the manuscript	contributed to acquisition of data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
3942566	24594114	ST	2	contributed to acquisition of data|performed the statistical analysis|interpreted the analysis and drafted the manuscript	performed the statistical analysis	Analyzed the data	Formal analysis	YES
3942566	24594114	ST	2	contributed to acquisition of data|performed the statistical analysis|interpreted the analysis and drafted the manuscript	interpreted the analysis and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5222900	27928713	AM	2	conceived the study, drafted the manuscript, participated in the design of the study and data collection, and performed the statistical analysis	conceived the study, drafted the manuscript, participated in the design of the study and data collection, and performed the statistical analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5222900	27928713	BP	2	conceived the study, drafted the manuscript, participated in the design of the study and data collection, and performed the statistical analysis|coordinated the study	conceived the study, drafted the manuscript, participated in the design of the study and data collection, and performed the statistical analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5222900	27928713	BP	2	conceived the study, drafted the manuscript, participated in the design of the study and data collection, and performed the statistical analysis|coordinated the study	coordinated the study	-	Project administration	YES
5222900	27928713	CL	2	conceived the study, drafted the manuscript, participated in the design of the study and data collection, and performed the statistical analysis	conceived the study, drafted the manuscript, participated in the design of the study and data collection, and performed the statistical analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5222900	27928713	MFM	2	conceived the study, drafted the manuscript, participated in the design of the study and data collection, and performed the statistical analysis	conceived the study, drafted the manuscript, participated in the design of the study and data collection, and performed the statistical analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5222900	27928713	TI	2	conceived the study, drafted the manuscript, participated in the design of the study and data collection, and performed the statistical analysis	conceived the study, drafted the manuscript, participated in the design of the study and data collection, and performed the statistical analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4262795	25538796	BK	2	all contributed to the proposal development	all contributed to the proposal development	-	-	NO
4262795	25538796	CC	2	all contributed to the proposal development|collected and analysed the data, contributed to the manuscript|contributed to data analysis and wrote the manuscript|contributed to manuscript preparation	all contributed to the proposal development	-	-	NO
4262795	25538796	CC	2	all contributed to the proposal development|collected and analysed the data, contributed to the manuscript|contributed to data analysis and wrote the manuscript|contributed to manuscript preparation	collected and analysed the data, contributed to the manuscript	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4262795	25538796	CC	2	all contributed to the proposal development|collected and analysed the data, contributed to the manuscript|contributed to data analysis and wrote the manuscript|contributed to manuscript preparation	contributed to data analysis and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4262795	25538796	CC	2	all contributed to the proposal development|collected and analysed the data, contributed to the manuscript|contributed to data analysis and wrote the manuscript|contributed to manuscript preparation	contributed to manuscript preparation	Wrote the paper	Writing - Original Draft	YES
4262795	25538796	DH	2	all contributed to the proposal development|contributed to manuscript preparation	all contributed to the proposal development	-	-	NO
4262795	25538796	DH	2	all contributed to the proposal development|contributed to manuscript preparation	contributed to manuscript preparation	Wrote the paper	Writing - Original Draft	YES
4262795	25538796	GW	2	all contributed to the proposal development	all contributed to the proposal development	-	-	NO
4262795	25538796	MD	2	all contributed to the proposal development	all contributed to the proposal development	-	-	NO
5465263	28649262	DaL	2	gave positive suggestion about this article	gave positive suggestion about this article	-	-	NO
5465263	28649262	DeL	2	revised the paper and gave positive suggestion	revised the paper and gave positive suggestion	Wrote the paper	Writing - Review & Editing	YES
5465263	28649262	QS	2	gave positive suggestion about this article	gave positive suggestion about this article	-	-	NO
5465263	28649262	XY	2	revised the paper and gave positive suggestion	revised the paper and gave positive suggestion	Wrote the paper	Writing - Review & Editing	YES
5465263	28649262	YL	2	wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
4433645	26064929	Brandon H. Cline	2	equally contributed to this work	equally contributed to this work	-	-	NO
4433645	26064929	Joao P. Costa-Nunes	2	equally contributed to this work	equally contributed to this work	-	-	NO
4400080	25881019	GF	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400080	25881019	HB	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400080	25881019	JB	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400080	25881019	JB	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400080	25881019	MH	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400080	25881019	MH	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400080	25881019	PC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400080	25881019	PC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400080	25881019	PC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400080	25881019	RG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400080	25881019	RG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400080	25881019	RG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400080	25881019	RG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3944639	24598459	CKL	2	contributed the patients data	contributed the patients data	Contributed reagents/materials/analysis tools	Resources	YES
3944639	24598459	DB	2	performed the data analysis	performed the data analysis	Analyzed the data	Formal analysis	YES
3944639	24598459	EY	2	contributed the patients data	contributed the patients data	Contributed reagents/materials/analysis tools	Resources	YES
3944639	24598459	FZ	2	contributed the patients data	contributed the patients data	Contributed reagents/materials/analysis tools	Resources	YES
3944639	24598459	JT	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
3944639	24598459	JYC	2	contributed the patients data	contributed the patients data	Contributed reagents/materials/analysis tools	Resources	YES
3944639	24598459	MM	2	contributed the patients data	contributed the patients data	Contributed reagents/materials/analysis tools	Resources	YES
3944639	24598459	ND	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
3944639	24598459	NK	2	contributed the patients data	contributed the patients data	Contributed reagents/materials/analysis tools	Resources	YES
3944639	24598459	OTN	2	drafted the manuscript|contributed the patients data	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
3944639	24598459	OTN	2	drafted the manuscript|contributed the patients data	contributed the patients data	Contributed reagents/materials/analysis tools	Resources	YES
3944639	24598459	PK	2	contributed the patients data	contributed the patients data	Contributed reagents/materials/analysis tools	Resources	YES
3944639	24598459	PP	2	contributed the patients data	contributed the patients data	Contributed reagents/materials/analysis tools	Resources	YES
3944639	24598459	RC	2	contributed the patients data	contributed the patients data	Contributed reagents/materials/analysis tools	Resources	YES
3944639	24598459	RD	2	contributed the patients data	contributed the patients data	Contributed reagents/materials/analysis tools	Resources	YES
3944639	24598459	SK	2	participated in the design of the study|drafted the manuscript|contributed the patients data	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
3944639	24598459	SK	2	participated in the design of the study|drafted the manuscript|contributed the patients data	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
3944639	24598459	SK	2	participated in the design of the study|drafted the manuscript|contributed the patients data	contributed the patients data	Contributed reagents/materials/analysis tools	Resources	YES
3944639	24598459	SP	2	contributed the patients data	contributed the patients data	Contributed reagents/materials/analysis tools	Resources	YES
3944639	24598459	SS	2	participated in the design of the study|drafted the manuscript	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
3944639	24598459	SS	2	participated in the design of the study|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
3944639	24598459	TPM	2	contributed the patients data	contributed the patients data	Contributed reagents/materials/analysis tools	Resources	YES
3944639	24598459	TTP	2	contributed the patients data	contributed the patients data	Contributed reagents/materials/analysis tools	Resources	YES
3944639	24598459	VS	2	contributed the patients data	contributed the patients data	Contributed reagents/materials/analysis tools	Resources	YES
3944639	24598459	WR	2	contributed the patients data	contributed the patients data	Contributed reagents/materials/analysis tools	Resources	YES
3944639	24598459	YAC	2	contributed the patients data	contributed the patients data	Contributed reagents/materials/analysis tools	Resources	YES
1828164	17343729	AK	2	designed the study, carried out analysis and writing the manuscript	designed the study, carried out analysis and writing the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
1828164	17343729	KRK	2	helped with the design of the study, entered the date into the computer database and cross checked the manuscript	helped with the design of the study, entered the date into the computer database and cross checked the manuscript	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Software|Validation|Writing - Review & Editing	YES
1828164	17343729	SF	2	helped with the collection of data	helped with the collection of data	Performed the experiments	Investigation	YES
1828164	17343729	SS	2	helped with the collection of data	helped with the collection of data	Performed the experiments	Investigation	YES
4400084	25879845	BS	PLoS5	Wrote the paper|Developed the software	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400084	25879845	BS	PLoS5	Wrote the paper|Developed the software	Developed the software	Contributed reagents/materials/analysis tools	Software	YES
4400084	25879845	EF	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400084	25879845	EH	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400084	25879845	EH	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400084	25879845	GKS	PLoS5	Conceived and designed the experiments|Wrote the paper|Developed the software	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400084	25879845	GKS	PLoS5	Conceived and designed the experiments|Wrote the paper|Developed the software	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400084	25879845	GKS	PLoS5	Conceived and designed the experiments|Wrote the paper|Developed the software	Developed the software	Contributed reagents/materials/analysis tools	Software	YES
4400084	25879845	HR	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper|Developed the biological example|Provided the gene ontology data	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400084	25879845	HR	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper|Developed the biological example|Provided the gene ontology data	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400084	25879845	HR	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper|Developed the biological example|Provided the gene ontology data	Developed the biological example	-	-	NO
4400084	25879845	HR	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper|Developed the biological example|Provided the gene ontology data	Provided the gene ontology data	Contributed reagents/materials/analysis tools	Resources	YES
4400084	25879845	MR	PLoS5	Wrote the paper|Provided the histone methylation data	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400084	25879845	MR	PLoS5	Wrote the paper|Provided the histone methylation data	Provided the histone methylation data	Contributed reagents/materials/analysis tools	Resources	YES
5465268	28649254	All of the authors	2	read and approved the manuscript	read and approved the manuscript	-	-	NO
5465268	28649254	DW	2	collected the data and assisted with data analysis	collected the data and assisted with data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5465268	28649254	HC	2	collected the data and assisted with data analysis	collected the data and assisted with data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5465268	28649254	JD	2	collected the data and assisted with data analysis	collected the data and assisted with data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5465268	28649254	MY	2	performed the experiments, analyzed the data and drafted the manuscript	performed the experiments, analyzed the data and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5465268	28649254	NG	2	collected the data and assisted with data analysis	collected the data and assisted with data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5465268	28649254	SR	2	designed the project and amended the manuscript	designed the project and amended the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5465268	28649254	SW	2	designed the project and amended the manuscript	designed the project and amended the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5465268	28649254	XG	2	designed the project and amended the manuscript	designed the project and amended the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5088524	27801291	All of the authors	2	contributed to the manuscripts preparation	contributed to the manuscripts preparation	Wrote the paper	Writing - Original Draft	YES
5088524	27801291	EP-W	2	contributed in the software development	contributed in the software development	Contributed reagents/materials/analysis tools	Software	YES
5088524	27801291	EU	2	contributed with the biological aspects of the paper	contributed with the biological aspects of the paper	-	-	NO
5088524	27801291	JA-M	2	contributed in the software development	contributed in the software development	Contributed reagents/materials/analysis tools	Software	YES
5088524	27801291	OT	2	supervised and coordinated the work and provided ideas for the development of new tools|supervised and coordinated the work and provided ideas for the development of new tools	supervised and coordinated the work and provided ideas for the development of new tools	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceptualization|Project administration|Resources|Supervision	YES
5088524	27801291	OT	2	supervised and coordinated the work and provided ideas for the development of new tools|supervised and coordinated the work and provided ideas for the development of new tools	supervised and coordinated the work and provided ideas for the development of new tools	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceptualization|Project administration|Resources|Supervision	YES
4293736	25598856	ABS	2	contributed to the drafting of the manuscript and the final critical revision	contributed to the drafting of the manuscript and the final critical revision	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4293736	25598856	GR	2	is the main author and responsible for the study conception as well as the design of the introduction and method sections|collected and analyzed the data in addition to drafting the manuscript and carrying out critical revisions	is the main author and responsible for the study conception as well as the design of the introduction and method sections	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
4293736	25598856	GR	2	is the main author and responsible for the study conception as well as the design of the introduction and method sections|collected and analyzed the data in addition to drafting the manuscript and carrying out critical revisions	collected and analyzed the data in addition to drafting the manuscript and carrying out critical revisions	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
4293736	25598856	IB	2	collected and analyzed data , drafted the manuscript and made critical revisions	collected and analyzed data , drafted the manuscript and made critical revisions	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
1828738	17352834	SC	2	participated in the design of the study	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
1828738	17352834	SL	2	participated in the design of the study	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
1828738	17352834	SS	2	participated in the design of the study and statistical analysis	participated in the design of the study and statistical analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
1828738	17352834	WM	2	participated in the design of the study and statistical analysis	participated in the design of the study and statistical analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
3946505	24629842	CA	PLoS52	designed the study|contributed to the data analysis and subsequent drafts of the article	designed the study	Conceived and designed the experiments	Methodology	YES
3946505	24629842	CA	PLoS52	designed the study|contributed to the data analysis and subsequent drafts of the article	contributed to the data analysis and subsequent drafts of the article	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3946505	24629842	CDS	PLoS52	designed the study|coordinated and monitored the study and wrote the first and subsequent drafts of the article|analysed the data	designed the study	Conceived and designed the experiments	Methodology	YES
3946505	24629842	CDS	PLoS52	designed the study|coordinated and monitored the study and wrote the first and subsequent drafts of the article|analysed the data	coordinated and monitored the study and wrote the first and subsequent drafts of the article	Wrote the paper	Project administration|Supervision|Writing - Original Draft	YES
3946505	24629842	CDS	PLoS52	designed the study|coordinated and monitored the study and wrote the first and subsequent drafts of the article|analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
3946505	24629842	HH	PLoS52	analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
3946505	24629842	IS	PLoS52	supervised study sites	supervised study sites	-	Supervision	YES
3946505	24629842	IVJ	PLoS52	contributed to the data analysis and subsequent drafts of the article	contributed to the data analysis and subsequent drafts of the article	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3946505	24629842	LG	PLoS52	contributed to the data analysis and subsequent drafts of the article	contributed to the data analysis and subsequent drafts of the article	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3946505	24629842	NC	PLoS52	supervised study sites	supervised study sites	-	Supervision	YES
3946505	24629842	NI	PLoS52	coordinated the laboratory testing	coordinated the laboratory testing	Performed the experiments	Investigation|Project administration	YES
3946505	24629842	NM	PLoS52	coordinated the laboratory testing	coordinated the laboratory testing	Performed the experiments	Investigation|Project administration	YES
3946505	24629842	OCJ	PLoS52	contributed to the data analysis and subsequent drafts of the article	contributed to the data analysis and subsequent drafts of the article	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4400096	25881205	CH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400096	25881205	CH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400096	25881205	CH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400096	25881205	JR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400096	25881205	JR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400096	25881205	JR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400096	25881205	JR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400096	25881205	JR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400096	25881205	JSJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400096	25881205	JSJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400096	25881205	JSJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400096	25881205	JSJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400096	25881205	JSJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400096	25881205	K. Seedorf	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400096	25881205	K. Seedorf	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400096	25881205	K. Strauss	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400096	25881205	K. Strauss	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5465270	28649259	CD	2	performed the experiment, processed the data, and wrote the manuscript|revised the manuscript	performed the experiment, processed the data, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Investigation|Writing - Original Draft	YES
5465270	28649259	CD	2	performed the experiment, processed the data, and wrote the manuscript|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5465270	28649259	JL	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5465270	28649259	ZC	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
509241	15260889	DHM	2	performed the statistical analysis of data	performed the statistical analysis of data	Analyzed the data	Formal analysis	YES
509241	15260889	SHD	2	conceived the study, provided overall direction and coordination to the research, and drafted the manuscript	conceived the study, provided overall direction and coordination to the research, and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Project administration|Supervision|Writing - Original Draft	YES
509241	15260889	SSJ	2	participated in the design and analysis of microarray-based experiments and in editing portions of the manuscript	participated in the design and analysis of microarray-based experiments and in editing portions of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
509241	15260889	YJ	2	carried out the microarray analysis	carried out the microarray analysis	Performed the experiments	Investigation	YES
509241	15260889	ZM	2	performed the pathology review and tissue dissection	performed the pathology review and tissue dissection	Performed the experiments	Investigation	YES
1832204	17359528	JEM	2	worked on the study grant and protocol, as well as provided reviews and input into the paper	worked on the study grant and protocol, as well as provided reviews and input into the paper	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
1832204	17359528	JM	2	assisted with the review and writing of the paper|also facilitated the data collection process, contacted the service providers and set appointmenets for the data collection	assisted with the review and writing of the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
1832204	17359528	JM	2	assisted with the review and writing of the paper|also facilitated the data collection process, contacted the service providers and set appointmenets for the data collection	also facilitated the data collection process, contacted the service providers and set appointmenets for the data collection	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Investigation|Resources	YES
1832204	17359528	NSM	2	assisted in writing the paper, protocol writing, data analysis, provided training and managed the team	assisted in writing the paper, protocol writing, data analysis, provided training and managed the team	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
1832204	17359528	VG	2	assisted with the data analysis, drafting of the paper and cleaning of the data sets	assisted with the data analysis, drafting of the paper and cleaning of the data sets	Analyzed the data|Wrote the paper	Data curation|Formal analysis|Writing - Original Draft	YES
3955761	24629847	QAK	2	jointly conceptualized and prepared this manuscript	jointly conceptualized and prepared this manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
3955761	24629847	RD	2	jointly conceptualized and prepared this manuscript	jointly conceptualized and prepared this manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4433648	26064941	David Aguilar	2	analyzed the morphology and immunohistochemical data	analyzed the morphology and immunohistochemical data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4433648	26064941	Elena Gonzalez-Rey	2	conceived, designed, and performed the mouse model, coordinated in the study, and drafted the paper	conceived, designed, and performed the mouse model, coordinated in the study, and drafted the paper	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Project administration|Writing - Original Draft	YES
4433648	26064941	Francisco Mesa	2	analyzed the clinical and biochemical data and drafted the paper	analyzed the clinical and biochemical data and drafted the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4433648	26064941	Jose Aneiros Fernandez	2	analyzed the morphology and immunohistochemical data	analyzed the morphology and immunohistochemical data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4433648	26064941	Magdalena Peregrina	2	analyzed the clinical and biochemical data and drafted the paper	analyzed the clinical and biochemical data and drafted the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4433648	26064941	Maria Roman	2	analyzed the clinical and biochemical data and drafted the paper	analyzed the clinical and biochemical data and drafted the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4433648	26064941	Mario Delgado	2	conceived, designed, and performed the mouse model, coordinated in the study, and drafted the paper	conceived, designed, and performed the mouse model, coordinated in the study, and drafted the paper	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Project administration|Writing - Original Draft	YES
4433648	26064941	Miguel Padial-Molina	2	analyzed the clinical and biochemical data and drafted the paper	analyzed the clinical and biochemical data and drafted the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4433648	26064941	OValle	2	conceived, designed, and performed the mouse model, coordinated in the study, and drafted the paper	conceived, designed, and performed the mouse model, coordinated in the study, and drafted the paper	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Project administration|Writing - Original Draft	YES
4433648	26064941	Pablo Galindo-Moreno	2	analyzed the clinical and biochemical data and drafted the paper	analyzed the clinical and biochemical data and drafted the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4433648	26064941	Pedro Hernandez-Cortes	2	conceived, designed, and performed the mouse model, coordinated in the study, and drafted the paper	conceived, designed, and performed the mouse model, coordinated in the study, and drafted the paper	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Project administration|Writing - Original Draft	YES
4433648	26064941	Vicente Crespo	2	analyzed the morphology and immunohistochemical data	analyzed the morphology and immunohistochemical data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5093950	27809787	ELN	2	helped with data analysis|participated in the discussions throughout the work and in writing parts of the paper	helped with data analysis	Analyzed the data	Formal analysis	YES
5093950	27809787	ELN	2	helped with data analysis|participated in the discussions throughout the work and in writing parts of the paper	participated in the discussions throughout the work and in writing parts of the paper	Wrote the paper	Writing - Original Draft	YES
5093950	27809787	FB	2	conceived the study, took care of most of the statistical analysis of data and writing of the manuscript	conceived the study, took care of most of the statistical analysis of data and writing of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
5093950	27809787	HP	2	contributed data for the analysis and information and insights on the mutation used as case study|participated in the discussions throughout the work and in writing parts of the paper	contributed data for the analysis and information and insights on the mutation used as case study	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5093950	27809787	HP	2	contributed data for the analysis and information and insights on the mutation used as case study|participated in the discussions throughout the work and in writing parts of the paper	participated in the discussions throughout the work and in writing parts of the paper	Wrote the paper	Writing - Original Draft	YES
5093950	27809787	HS	2	contributed data for the analysis and information and insights on the mutation used as case study|participated in the discussions throughout the work and in writing parts of the paper	contributed data for the analysis and information and insights on the mutation used as case study	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5093950	27809787	HS	2	contributed data for the analysis and information and insights on the mutation used as case study|participated in the discussions throughout the work and in writing parts of the paper	participated in the discussions throughout the work and in writing parts of the paper	Wrote the paper	Writing - Original Draft	YES
5093950	27809787	SB	2	conceived the study, took care of most of the statistical analysis of data and writing of the manuscript	conceived the study, took care of most of the statistical analysis of data and writing of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
5093950	27809787	YP	2	participated in the discussions throughout the work and in writing parts of the paper	participated in the discussions throughout the work and in writing parts of the paper	Wrote the paper	Writing - Original Draft	YES
1868754	17472747	AB	2	performed the western immunoblot analyses	performed the western immunoblot analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
1868754	17472747	AR	2	treated and monitored the animals and collected food and water data	treated and monitored the animals and collected food and water data	Performed the experiments	Investigation|Supervision	YES
1868754	17472747	DJ	2	treated and monitored the animals and collected food and water data	treated and monitored the animals and collected food and water data	Performed the experiments	Investigation|Supervision	YES
1868754	17472747	EK	2	treated and monitored the animals and collected food and water data	treated and monitored the animals and collected food and water data	Performed the experiments	Investigation|Supervision	YES
1868754	17472747	KA	2	performed the elisas and blood work	performed the elisas and blood work	Performed the experiments	Investigation	YES
1868754	17472747	MW	2	conceived the study and participated in its design and coordination|wrote the manuscript	conceived the study and participated in its design and coordination	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
1868754	17472747	MW	2	conceived the study and participated in its design and coordination|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3955762	24629844	All authors	2	contributed to the conceptualization of this study|contributed to the analysis|contributed to the critical revision of the manuscript and approved the final version	contributed to the conceptualization of this study	Conceived and designed the experiments	Conceptualization	YES
3955762	24629844	All authors	2	contributed to the conceptualization of this study|contributed to the analysis|contributed to the critical revision of the manuscript and approved the final version	contributed to the analysis	-	-	NO
3955762	24629844	All authors	2	contributed to the conceptualization of this study|contributed to the analysis|contributed to the critical revision of the manuscript and approved the final version	contributed to the critical revision of the manuscript and approved the final version	Wrote the paper	Writing - Review & Editing	YES
3955762	24629844	RM	2	conducted the interviews|wrote the first draft of the manuscript	conducted the interviews	Performed the experiments	Investigation	YES
3955762	24629844	RM	2	conducted the interviews|wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
5465300	28649264	AZ	2	drafted the work and revised the manuscript	drafted the work and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5465300	28649264	BX	2	substantial contributed to the conception and design of the work	substantial contributed to the conception and design of the work	Conceived and designed the experiments	Conceptualization	YES
5465300	28649264	GX	2	drafted the work and revised the manuscript	drafted the work and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5465300	28649264	HY	2	drafted the work and revised the manuscript	drafted the work and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5465300	28649264	JC	2	drafted the work and revised the manuscript	drafted the work and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5465300	28649264	LH	2	substantial contributed to the conception and design of the work	substantial contributed to the conception and design of the work	Conceived and designed the experiments	Conceptualization	YES
5465300	28649264	XH	2	drafted the work and revised the manuscript	drafted the work and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5465300	28649264	XZ	2	substantial contributed to the conception and design of the work	substantial contributed to the conception and design of the work	Conceived and designed the experiments	Conceptualization	YES
5465300	28649264	ZM	2	drafted the work and revised the manuscript	drafted the work and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4400097	25880684	BIT	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400097	25880684	BIT	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400097	25880684	BIT	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400097	25880684	HKN	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400097	25880684	JFS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400097	25880684	JFS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400097	25880684	MAV	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4400097	25880684	MAV	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4400097	25880684	MAV	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400097	25880684	SG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400097	25880684	SG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400097	25880684	SG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400097	25880684	SG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400097	25880684	SG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4382558	25852785	AK	1	Study design|Manuscript preparation	Study design	Conceived and designed the experiments	Methodology	YES
4382558	25852785	AK	1	Study design|Manuscript preparation	Manuscript preparation	Wrote the paper	Writing - Original Draft	YES
4382558	25852785	IJ	1	Study design|Manuscript preparation	Study design	Conceived and designed the experiments	Methodology	YES
4382558	25852785	IJ	1	Study design|Manuscript preparation	Manuscript preparation	Wrote the paper	Writing - Original Draft	YES
4382558	25852785	RAM	1	Data collection|Manuscript preparation	Data collection	Performed the experiments	Investigation	YES
4382558	25852785	RAM	1	Data collection|Manuscript preparation	Manuscript preparation	Wrote the paper	Writing - Original Draft	YES
3955763	24629846	The authors	2	had discussions on the manuscript and came up with action items to be explored in the viewpoint|jointly wrote and edited the manuscript	had discussions on the manuscript and came up with action items to be explored in the viewpoint	-	-	NO
3955763	24629846	The authors	2	had discussions on the manuscript and came up with action items to be explored in the viewpoint|jointly wrote and edited the manuscript	jointly wrote and edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4400099	25880638	AAT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400099	25880638	AAT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4400099	25880638	AAT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4400099	25880638	GAC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400099	25880638	JJR	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400099	25880638	JJR	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400099	25880638	KH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400099	25880638	KH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400099	25880638	KH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400099	25880638	KH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400099	25880638	KK	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1871602	17488505	All authors	2	participated in the drafting of the manuscript	participated in the drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
3956311	24629843	CM	2	contributed to data collection and to critical comments on the final manuscript	contributed to data collection and to critical comments on the final manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
3956311	24629843	DM	2	contributed vision, design, implementation, data analysis, and manuscript writing	contributed vision, design, implementation, data analysis, and manuscript writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft	YES
3956311	24629843	PM	2	contributed to design, implementation, and to critical manuscript comments	contributed to design, implementation, and to critical manuscript comments	Conceived and designed the experiments|Performed the experiments	Investigation	YES
3956311	24629843	TC	2	contributed to the implementation, data analysis, and manuscript writing	contributed to the implementation, data analysis, and manuscript writing	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft	YES
3956311	24629843	TL	2	contributed to data collection and to critical comments on the final manuscript	contributed to data collection and to critical comments on the final manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5093955	27809782	AF	2	carried out diagnostics and experiments	carried out diagnostics and experiments	Performed the experiments	Investigation	YES
5093955	27809782	CE	2	conceived the study|conducted the data analysis	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5093955	27809782	CE	2	conceived the study|conducted the data analysis	conducted the data analysis	Analyzed the data	Formal analysis	YES
5093955	27809782	TE	2	conceived the study|carried out diagnostics and experiments|conducted the data analysis|wrote the manuscript and all the authors read and approved the final manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5093955	27809782	TE	2	conceived the study|carried out diagnostics and experiments|conducted the data analysis|wrote the manuscript and all the authors read and approved the final manuscript	carried out diagnostics and experiments	Performed the experiments	Investigation	YES
5093955	27809782	TE	2	conceived the study|carried out diagnostics and experiments|conducted the data analysis|wrote the manuscript and all the authors read and approved the final manuscript	conducted the data analysis	Analyzed the data	Formal analysis	YES
5093955	27809782	TE	2	conceived the study|carried out diagnostics and experiments|conducted the data analysis|wrote the manuscript and all the authors read and approved the final manuscript	wrote the manuscript and all the authors read and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5093955	27809782	TS	2	conceived the study|carried out diagnostics and experiments|conducted the data analysis	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5093955	27809782	TS	2	conceived the study|carried out diagnostics and experiments|conducted the data analysis	carried out diagnostics and experiments	Performed the experiments	Investigation	YES
5093955	27809782	TS	2	conceived the study|carried out diagnostics and experiments|conducted the data analysis	conducted the data analysis	Analyzed the data	Formal analysis	YES
5093955	27809782	WN	2	carried out diagnostics and experiments	carried out diagnostics and experiments	Performed the experiments	Investigation	YES
4400100	25881059	AK	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400100	25881059	AK	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400100	25881059	BM	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400100	25881059	BM	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400100	25881059	GJW	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400100	25881059	GJW	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400100	25881059	HH	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400100	25881059	HH	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400100	25881059	HT	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400100	25881059	HT	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400100	25881059	JH	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400100	25881059	JH	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400100	25881059	PW	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400100	25881059	PW	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400100	25881059	PW	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400100	25881059	PW	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400100	25881059	SL	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400100	25881059	SL	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400100	25881059	SL	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400100	25881059	YR	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400100	25881059	YR	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400100	25881059	YR	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5465302	28649263	KS	PLoS52	analyzed the data|finalized the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5465302	28649263	KS	PLoS52	analyzed the data|finalized the manuscript	finalized the manuscript	Wrote the paper	Writing - Review & Editing	YES
5465302	28649263	MT	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5465302	28649263	MT	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5465302	28649263	SKU	PLoS52	conceived the idea and designed the experiments|finalized the manuscript	conceived the idea and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5465302	28649263	SKU	PLoS52	conceived the idea and designed the experiments|finalized the manuscript	finalized the manuscript	Wrote the paper	Writing - Review & Editing	YES
5465302	28649263	ST	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5465302	28649263	ST	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
3062932	21291287	Both authors	2	contributed equally to this work	contributed equally to this work	-	-	NO
4400104	25881064	AB	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400104	25881064	AB	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400104	25881064	AI	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4400104	25881064	DB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4400104	25881064	FF	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4400104	25881064	GCP	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400104	25881064	GJG	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400104	25881064	GMG	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4400104	25881064	IS	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4400104	25881064	MD	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4400104	25881064	MP	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400104	25881064	MV	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400104	25881064	PP	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400104	25881064	PP	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400104	25881064	SE	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4400104	25881064	VV	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
3956312	24629845	CH	2	coordinated data collection	coordinated data collection	Performed the experiments	Investigation|Project administration	YES
3956312	24629845	DR	2	critically reviewed drafts and contributed to the content	critically reviewed drafts and contributed to the content	Wrote the paper	Writing - Original Draft	YES
3956312	24629845	EDL	2	critically reviewed drafts and contributed to the content	critically reviewed drafts and contributed to the content	Wrote the paper	Writing - Original Draft	YES
3956312	24629845	FC	2	designed the protocol|critically reviewed drafts and contributed to the content	designed the protocol	Conceived and designed the experiments	Methodology	YES
3956312	24629845	FC	2	designed the protocol|critically reviewed drafts and contributed to the content	critically reviewed drafts and contributed to the content	Wrote the paper	Writing - Original Draft	YES
3956312	24629845	GM	2	coordinated data collection|participated in coding and interpreting data	coordinated data collection	Performed the experiments	Investigation|Project administration	YES
3956312	24629845	GM	2	coordinated data collection|participated in coding and interpreting data	participated in coding and interpreting data	Analyzed the data	Formal analysis	YES
3956312	24629845	IH	2	coordinated data collection|participated in coding and interpreting data	coordinated data collection	Performed the experiments	Investigation|Project administration	YES
3956312	24629845	IH	2	coordinated data collection|participated in coding and interpreting data	participated in coding and interpreting data	Analyzed the data	Formal analysis	YES
3956312	24629845	SK	2	critically reviewed drafts and contributed to the content	critically reviewed drafts and contributed to the content	Wrote the paper	Writing - Original Draft	YES
5093961	27809775	AS	2	wrote and deployed the algorithms used for statistical testing	wrote and deployed the algorithms used for statistical testing	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Software|Writing - Original Draft	YES
5093961	27809775	CJM	2	collated and analyzed published data on recombination breakpoints|mapped and analyzed pqss in plasmodium genomes|made and analyzed the helicase alignments|designed the study and wrote the manuscript	collated and analyzed published data on recombination breakpoints	Analyzed the data	Data curation|Formal analysis	YES
5093961	27809775	CJM	2	collated and analyzed published data on recombination breakpoints|mapped and analyzed pqss in plasmodium genomes|made and analyzed the helicase alignments|designed the study and wrote the manuscript	mapped and analyzed pqss in plasmodium genomes	Analyzed the data	Formal analysis	YES
5093961	27809775	CJM	2	collated and analyzed published data on recombination breakpoints|mapped and analyzed pqss in plasmodium genomes|made and analyzed the helicase alignments|designed the study and wrote the manuscript	made and analyzed the helicase alignments	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5093961	27809775	CJM	2	collated and analyzed published data on recombination breakpoints|mapped and analyzed pqss in plasmodium genomes|made and analyzed the helicase alignments|designed the study and wrote the manuscript	designed the study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5093961	27809775	GG	2	collated and analyzed published data on recombination breakpoints	collated and analyzed published data on recombination breakpoints	Analyzed the data	Data curation|Formal analysis	YES
5093961	27809775	LH	2	collated and analyzed published data on recombination breakpoints|mapped and analyzed pqss in plasmodium genomes	collated and analyzed published data on recombination breakpoints	Analyzed the data	Data curation|Formal analysis	YES
5093961	27809775	LH	2	collated and analyzed published data on recombination breakpoints|mapped and analyzed pqss in plasmodium genomes	mapped and analyzed pqss in plasmodium genomes	Analyzed the data	Formal analysis	YES
4400105	25881132	AK	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400105	25881132	AK	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400105	25881132	AK	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400105	25881132	CNM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400105	25881132	CNM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400105	25881132	CNM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400105	25881132	CNM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400105	25881132	DM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400105	25881132	DM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400105	25881132	DM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400105	25881132	MESB	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400105	25881132	MESB	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400105	25881132	RHW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400105	25881132	RHW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400105	25881132	RHW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400105	25881132	SLW	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400105	25881132	SLW	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400105	25881132	SLW	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400105	25881132	TV	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400105	25881132	TV	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400105	25881132	TV	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400105	25881132	TV	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5465304	28659934	AB	2	conceived, wrote, and organized the manuscript	conceived, wrote, and organized the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5465304	28659934	All authors	2	contributed to writing the manuscript	contributed to writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5465304	28659934	DC	2	conceived, wrote, and organized the manuscript	conceived, wrote, and organized the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
3959275	24647205	CMO	PLoS5	Conceived and designed the study|Analyzed the data|Wrote the first draft of the manuscript|Revised and finalized the manuscript	Conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3959275	24647205	CMO	PLoS5	Conceived and designed the study|Analyzed the data|Wrote the first draft of the manuscript|Revised and finalized the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
3959275	24647205	CMO	PLoS5	Conceived and designed the study|Analyzed the data|Wrote the first draft of the manuscript|Revised and finalized the manuscript	Wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
3959275	24647205	CMO	PLoS5	Conceived and designed the study|Analyzed the data|Wrote the first draft of the manuscript|Revised and finalized the manuscript	Revised and finalized the manuscript	Wrote the paper	Writing - Review & Editing	YES
3959275	24647205	CV	PLoS5	Analyzed the data|Wrote the first draft of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
3959275	24647205	CV	PLoS5	Analyzed the data|Wrote the first draft of the manuscript	Wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
3959275	24647205	KA	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5093966	27806685	AH	2	designed the study and participated in its coordination	designed the study and participated in its coordination	Conceived and designed the experiments	Methodology|Project administration	YES
5093966	27806685	CGW	2	designed the study and participated in its coordination	designed the study and participated in its coordination	Conceived and designed the experiments	Methodology|Project administration	YES
5093966	27806685	CRB	2	designed the study and participated in its coordination	designed the study and participated in its coordination	Conceived and designed the experiments	Methodology|Project administration	YES
5093966	27806685	JKK	2	designed the study and participated in its coordination	designed the study and participated in its coordination	Conceived and designed the experiments	Methodology|Project administration	YES
5093966	27806685	MAC	2	extracted and quality-assessed the rna from the biopsy samples	extracted and quality-assessed the rna from the biopsy samples	Performed the experiments	Investigation|Validation	YES
5093966	27806685	MDM	2	designed the study and participated in its coordination	designed the study and participated in its coordination	Conceived and designed the experiments	Methodology|Project administration	YES
5093966	27806685	SLRZ	2	handled the statistical analysis of the array results	handled the statistical analysis of the array results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5093966	27806685	SM	2	designed the study and participated in its coordination	designed the study and participated in its coordination	Conceived and designed the experiments	Methodology|Project administration	YES
4400106	25881269	CCS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400106	25881269	CCS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400106	25881269	DAW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400106	25881269	DAW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400106	25881269	DAW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400106	25881269	JWH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400106	25881269	JWH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400106	25881269	JWH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400106	25881269	JWH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400106	25881269	RMK	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400106	25881269	RMK	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1896176	17559655	ACP	2	was in charge of the inpatient/outpatient care, supervised the study, drafted the manuscript, analyzed the data, and made critical intellectual contributions	was in charge of the inpatient/outpatient care, supervised the study, drafted the manuscript, analyzed the data, and made critical intellectual contributions	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Supervision|Writing - Original Draft	YES
1896176	17559655	BKV	2	proteins, and drafted the manuscript|proteins, and drafted the manuscript	proteins, and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
1896176	17559655	BKV	2	proteins, and drafted the manuscript|proteins, and drafted the manuscript	proteins, and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
1896176	17559655	CSF	2	drafted the manuscript|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
1896176	17559655	CSF	2	drafted the manuscript|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
1896176	17559655	EEC	2	performed the morphological analysis and histopathological studies	performed the morphological analysis and histopathological studies	Performed the experiments	Investigation	YES
1896176	17559655	FBF	2	was in charge of the inpatient management of the patient, and collected the data and analyzed it	was in charge of the inpatient management of the patient, and collected the data and analyzed it	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
1896176	17559655	FCD	2	participated in the design and drafting of manuscript, collected the data, and made critical intellectual contributions	participated in the design and drafting of manuscript, collected the data, and made critical intellectual contributions	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
1896176	17559655	JCV	2	proteins, and drafted the manuscript|proteins, and drafted the manuscript	proteins, and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
1896176	17559655	JCV	2	proteins, and drafted the manuscript|proteins, and drafted the manuscript	proteins, and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
1896176	17559655	JEV	2	was in charge of the inpatient/outpatient care, management collected and analyzed all the data, drafted the manuscript, and made critical intellectual contributions	was in charge of the inpatient/outpatient care, management collected and analyzed all the data, drafted the manuscript, and made critical intellectual contributions	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Formal analysis|Investigation|Writing - Original Draft	YES
1896176	17559655	JRT	2	designed and drafted the manuscript, supervised the study, and made critical intellectual contributions	designed and drafted the manuscript, supervised the study, and made critical intellectual contributions	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Original Draft	YES
1896176	17559655	RD	2	performed the stereotactic biopsy and made intellectual contributions to the manuscript	performed the stereotactic biopsy and made intellectual contributions to the manuscript	Performed the experiments	Investigation	YES
1896176	17559655	RSN	2	was in charge of the inpatient management of the patient, collected the data and analyzed it	was in charge of the inpatient management of the patient, collected the data and analyzed it	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
3962027	24650763	CES	PLoS5	Contributed to drafting the manuscript	Contributed to drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
3962027	24650763	KLD	PLoS5	Conceptualized and designed this study|Analyzed the data|Contributed to drafting the manuscript	Conceptualized and designed this study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3962027	24650763	KLD	PLoS5	Conceptualized and designed this study|Analyzed the data|Contributed to drafting the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
3962027	24650763	KLD	PLoS5	Conceptualized and designed this study|Analyzed the data|Contributed to drafting the manuscript	Contributed to drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
3962027	24650763	MN	PLoS5	Participated in the design of the study, the data collection, and contributed to the manuscript draft	Participated in the design of the study, the data collection, and contributed to the manuscript draft	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
3962027	24650763	NJC	PLoS5	Conceptualized and designed this study|Wrote the first draft of the manuscript|Analyzed the data	Conceptualized and designed this study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3962027	24650763	NJC	PLoS5	Conceptualized and designed this study|Wrote the first draft of the manuscript|Analyzed the data	Wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
3962027	24650763	NJC	PLoS5	Conceptualized and designed this study|Wrote the first draft of the manuscript|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
3962027	24650763	NJS	PLoS5	Participated in the design of the study, the data collection, and contributed to the manuscript draft	Participated in the design of the study, the data collection, and contributed to the manuscript draft	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
3962027	24650763	RKJ	PLoS5	Conceptualized and designed this study	Conceptualized and designed this study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5465369	28649256	BS	2	collected maintained and genotyped wild rice	collected maintained and genotyped wild rice	Performed the experiments	Investigation	YES
5465369	28649256	NKS	2	conceptualized, supervised the study, edited and finalized the manuscript	conceptualized, supervised the study, edited and finalized the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Supervision|Writing - Review & Editing	YES
5465369	28649256	NS	2	conceptualized, designed and conducted the experiments and prepared the manuscript	conceptualized, designed and conducted the experiments and prepared the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Writing - Original Draft	YES
5093967	27809788	AF	2	optimised the facs procedure and protoplast collection for rna isolation and analysed the rna seq data	optimised the facs procedure and protoplast collection for rna isolation and analysed the rna seq data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5093967	27809788	ATA	2	processed the deep-sequencing data and performed quality control and anchoring of sequence reads to the arabidopsis genome	processed the deep-sequencing data and performed quality control and anchoring of sequence reads to the arabidopsis genome	Performed the experiments|Analyzed the data	Data curation|Investigation|Validation	YES
5093967	27809788	JWC	2	conceived the study, co-wrote the manuscript and analysed the rna seq data	conceived the study, co-wrote the manuscript and analysed the rna seq data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
5093967	27809788	PF	2	processed the deep-sequencing data and performed quality control and anchoring of sequence reads to the arabidopsis genome	processed the deep-sequencing data and performed quality control and anchoring of sequence reads to the arabidopsis genome	Performed the experiments|Analyzed the data	Data curation|Investigation|Validation	YES
5093967	27809788	RT	2	established the facs methodology	established the facs methodology	Performed the experiments	Methodology	YES
5093967	27809788	WW	2	supervised facs experiments and rna isolation and co-wrote the manuscript	supervised facs experiments and rna isolation and co-wrote the manuscript	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Original Draft	YES
1934375	17597538	All authors	2	were involved in drafting the manuscript and provided extensive comments and review|performed analysis and interpretation of data	were involved in drafting the manuscript and provided extensive comments and review	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
1934375	17597538	All authors	2	were involved in drafting the manuscript and provided extensive comments and review|performed analysis and interpretation of data	performed analysis and interpretation of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4400109	25880431	JS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400109	25880431	JS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400109	25880431	JS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400109	25880431	MH	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400109	25880431	MH	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400109	25880431	OD	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400109	25880431	OD	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4400109	25880431	PT	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400109	25880431	PT	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400109	25880431	PT	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400109	25880431	SV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400109	25880431	SV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400109	25880431	SV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400109	25880431	SV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400109	25880431	VM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4400109	25880431	VT	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5465376	28649255	DQ	2	designed experiments	designed experiments	Conceived and designed the experiments	Methodology	YES
5465376	28649255	FS	2	carried out experiments and analyzed experimental results|wrote the manuscript	carried out experiments and analyzed experimental results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5465376	28649255	FS	2	carried out experiments and analyzed experimental results|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5465376	28649255	XY	2	designed experiments	designed experiments	Conceived and designed the experiments	Methodology	YES
3965711	24666594	AR	2	contributed to analysis	contributed to analysis	-	-	NO
3965711	24666594	BZ	2	contributed to interpreting findings	contributed to interpreting findings	Analyzed the data	Formal analysis	YES
3965711	24666594	FC	2	contributed to interpreting findings	contributed to interpreting findings	Analyzed the data	Formal analysis	YES
3965711	24666594	JC	2	contributed to data collection	contributed to data collection	Performed the experiments	Investigation	YES
3965711	24666594	JV	2	originated the study|supervised all aspects of its implementation|contributed to data collection|contributed to interpreting findings	originated the study	Conceived and designed the experiments	Conceptualization	YES
3965711	24666594	JV	2	originated the study|supervised all aspects of its implementation|contributed to data collection|contributed to interpreting findings	supervised all aspects of its implementation	Performed the experiments	Investigation|Supervision	YES
3965711	24666594	JV	2	originated the study|supervised all aspects of its implementation|contributed to data collection|contributed to interpreting findings	contributed to data collection	Performed the experiments	Investigation	YES
3965711	24666594	JV	2	originated the study|supervised all aspects of its implementation|contributed to data collection|contributed to interpreting findings	contributed to interpreting findings	Analyzed the data	Formal analysis	YES
3965711	24666594	KS	2	originated the study|supervised all aspects of its implementation|contributed to analysis|contributed to interpreting findings	originated the study	Conceived and designed the experiments	Conceptualization	YES
3965711	24666594	KS	2	originated the study|supervised all aspects of its implementation|contributed to analysis|contributed to interpreting findings	supervised all aspects of its implementation	Performed the experiments	Investigation|Supervision	YES
3965711	24666594	KS	2	originated the study|supervised all aspects of its implementation|contributed to analysis|contributed to interpreting findings	contributed to analysis	-	-	NO
3965711	24666594	KS	2	originated the study|supervised all aspects of its implementation|contributed to analysis|contributed to interpreting findings	contributed to interpreting findings	Analyzed the data	Formal analysis	YES
3965711	24666594	MM	2	contributed to interpreting findings	contributed to interpreting findings	Analyzed the data	Formal analysis	YES
3965711	24666594	S Gimbel	2	originated the study|supervised all aspects of its implementation|contributed to analysis|contributed to interpreting findings|wrote the manuscript and is its guarantor	originated the study	Conceived and designed the experiments	Conceptualization	YES
3965711	24666594	S Gimbel	2	originated the study|supervised all aspects of its implementation|contributed to analysis|contributed to interpreting findings|wrote the manuscript and is its guarantor	supervised all aspects of its implementation	Performed the experiments	Investigation|Supervision	YES
3965711	24666594	S Gimbel	2	originated the study|supervised all aspects of its implementation|contributed to analysis|contributed to interpreting findings|wrote the manuscript and is its guarantor	contributed to analysis	-	-	NO
3965711	24666594	S Gimbel	2	originated the study|supervised all aspects of its implementation|contributed to analysis|contributed to interpreting findings|wrote the manuscript and is its guarantor	contributed to interpreting findings	Analyzed the data	Formal analysis	YES
3965711	24666594	S Gimbel	2	originated the study|supervised all aspects of its implementation|contributed to analysis|contributed to interpreting findings|wrote the manuscript and is its guarantor	wrote the manuscript and is its guarantor	Wrote the paper	Writing - Original Draft	YES
3965711	24666594	S Gloyd	2	contributed to interpreting findings	contributed to interpreting findings	Analyzed the data	Formal analysis	YES
3965711	24666594	SG	2	contributed to data collection	contributed to data collection	Performed the experiments	Investigation	YES
1959238	17620130	AM	2	participated in study design and coordination, data collection and preparation of manuscript	participated in study design and coordination, data collection and preparation of manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Project administration|Writing - Original Draft	YES
1959238	17620130	AP	2	participated in study design, statistical analysis, and preparation of manuscript	participated in study design, statistical analysis, and preparation of manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
1959238	17620130	CL	2	carried out the data collection	carried out the data collection	Performed the experiments	Investigation	YES
1959238	17620130	PWW	2	participated in study design and coordination	participated in study design and coordination	Conceived and designed the experiments	Methodology|Project administration	YES
1959238	17620130	SG	2	participated in study design and coordination	participated in study design and coordination	Conceived and designed the experiments	Methodology|Project administration	YES
4400117	25879540	AN	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4400117	25879540	BV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400117	25879540	BV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400117	25879540	BV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400117	25879540	BV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400117	25879540	CR	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400117	25879540	GB	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400117	25879540	KM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400117	25879540	KM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400117	25879540	KM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400117	25879540	MH	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400117	25879540	RM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400117	25879540	RM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400117	25879540	RM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400117	25879540	RM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400117	25879540	RM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5465953	28649260	AB	2	conceived and designed the research	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5465953	28649260	AF	2	conceived and designed the research|performed data collection, analysis and interpretation, and wrote the manuscript	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5465953	28649260	AF	2	conceived and designed the research|performed data collection, analysis and interpretation, and wrote the manuscript	performed data collection, analysis and interpretation, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5465953	28649260	JL	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5465953	28649260	KR-E	2	carried out the experiments|performed data collection, analysis and interpretation, and wrote the manuscript	carried out the experiments	Performed the experiments	Investigation	YES
5465953	28649260	KR-E	2	carried out the experiments|performed data collection, analysis and interpretation, and wrote the manuscript	performed data collection, analysis and interpretation, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5465953	28649260	MA	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5465953	28649260	NC	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5465953	28649260	TA	2	conceived and designed the research|performed data collection, analysis and interpretation, and wrote the manuscript	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5465953	28649260	TA	2	conceived and designed the research|performed data collection, analysis and interpretation, and wrote the manuscript	performed data collection, analysis and interpretation, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5093975	27806710	AD	2	conceived the study and designed experiments|performed experiments|analyzed and discussed data|wrote the manuscript	conceived the study and designed experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5093975	27806710	AD	2	conceived the study and designed experiments|performed experiments|analyzed and discussed data|wrote the manuscript	performed experiments	Performed the experiments	Investigation	YES
5093975	27806710	AD	2	conceived the study and designed experiments|performed experiments|analyzed and discussed data|wrote the manuscript	analyzed and discussed data	Analyzed the data	Formal analysis	YES
5093975	27806710	AD	2	conceived the study and designed experiments|performed experiments|analyzed and discussed data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5093975	27806710	DW	2	analyzed and discussed data|wrote the manuscript	analyzed and discussed data	Analyzed the data	Formal analysis	YES
5093975	27806710	DW	2	analyzed and discussed data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5093975	27806710	EB	2	performed computational analyses	performed computational analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5093975	27806710	GM	2	conceived the study and designed experiments|analyzed and discussed data|wrote the manuscript	conceived the study and designed experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5093975	27806710	GM	2	conceived the study and designed experiments|analyzed and discussed data|wrote the manuscript	analyzed and discussed data	Analyzed the data	Formal analysis	YES
5093975	27806710	GM	2	conceived the study and designed experiments|analyzed and discussed data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5093975	27806710	JCE	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5093975	27806710	KU	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5093975	27806710	ME	2	performed computational analyses|wrote the manuscript	performed computational analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5093975	27806710	ME	2	performed computational analyses|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5093975	27806710	NE	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5093975	27806710	RM	2	performed computational analyses	performed computational analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5093975	27806710	SRH	2	performed computational analyses	performed computational analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5093975	27806710	SW	2	performed experiments|analyzed and discussed data|wrote the manuscript	performed experiments	Performed the experiments	Investigation	YES
5093975	27806710	SW	2	performed experiments|analyzed and discussed data|wrote the manuscript	analyzed and discussed data	Analyzed the data	Formal analysis	YES
5093975	27806710	SW	2	performed experiments|analyzed and discussed data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3969508	24679634	BM	2	provided guidance during the conception of the study, and provided substantive and editorial assistance for subsequent drafts	provided guidance during the conception of the study, and provided substantive and editorial assistance for subsequent drafts	Conceived and designed the experiments|Wrote the paper	Conceptualization|Supervision|Writing - Original Draft	YES
3969508	24679634	CH	2	provided guidance during the conception of the study, and provided substantive and editorial assistance for subsequent drafts	provided guidance during the conception of the study, and provided substantive and editorial assistance for subsequent drafts	Conceived and designed the experiments|Wrote the paper	Conceptualization|Supervision|Writing - Original Draft	YES
3969508	24679634	DE	2	conceived and drafted the original version of the manuscript	conceived and drafted the original version of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
3969508	24679634	ML	2	provided assistance in the interpretation of the current literature and review that gave rise to this manuscript, and contributed to revisions of earlier drafts	provided assistance in the interpretation of the current literature and review that gave rise to this manuscript, and contributed to revisions of earlier drafts	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
3969508	24679634	TK	2	provided assistance in the interpretation of the current literature and review that gave rise to this manuscript, and contributed to revisions of earlier drafts	provided assistance in the interpretation of the current literature and review that gave rise to this manuscript, and contributed to revisions of earlier drafts	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
1988803	17634130	All authors	2	were involved in drafting the manuscript and provided extensive comments and review|performed analysis and interpretation of data	were involved in drafting the manuscript and provided extensive comments and review	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
1988803	17634130	All authors	2	were involved in drafting the manuscript and provided extensive comments and review|performed analysis and interpretation of data	performed analysis and interpretation of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4400123	25880985	AC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400123	25880985	AC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400123	25880985	AC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400123	25880985	AC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400123	25880985	AC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400123	25880985	AG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400123	25880985	AG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400123	25880985	AG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400123	25880985	AG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400123	25880985	AG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400123	25880985	AJ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400123	25880985	AJ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400123	25880985	AJ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400123	25880985	AJ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400123	25880985	LC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400123	25880985	LC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400123	25880985	LC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400123	25880985	LC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400123	25880985	LC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400123	25880985	ODG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400123	25880985	ODG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400123	25880985	ODG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400123	25880985	ODG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400123	25880985	ODG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400123	25880985	OG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400123	25880985	OG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400123	25880985	OG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400123	25880985	OG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400123	25880985	OG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400123	25880985	RC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400123	25880985	RC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400123	25880985	RC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400123	25880985	RC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400123	25880985	RC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400123	25880985	VG	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400123	25880985	VG	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400123	25880985	VG	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400123	25880985	VG	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4894944	27347252	AO	1	Study design|Data analysis|Writing of the manuscript	Study design	Conceived and designed the experiments	Methodology	YES
4894944	27347252	AO	1	Study design|Data analysis|Writing of the manuscript	Data analysis	Analyzed the data	Formal analysis	YES
4894944	27347252	AO	1	Study design|Data analysis|Writing of the manuscript	Writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
4894944	27347252	ER	1	Study design|Data collection|Data analysis|Writing of the manuscript	Study design	Conceived and designed the experiments	Methodology	YES
4894944	27347252	ER	1	Study design|Data collection|Data analysis|Writing of the manuscript	Data collection	Performed the experiments	Investigation	YES
4894944	27347252	ER	1	Study design|Data collection|Data analysis|Writing of the manuscript	Data analysis	Analyzed the data	Formal analysis	YES
4894944	27347252	ER	1	Study design|Data collection|Data analysis|Writing of the manuscript	Writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
4894944	27347252	LJ	1	Study design|Data analysis|Writing of the manuscript	Study design	Conceived and designed the experiments	Methodology	YES
4894944	27347252	LJ	1	Study design|Data analysis|Writing of the manuscript	Data analysis	Analyzed the data	Formal analysis	YES
4894944	27347252	LJ	1	Study design|Data analysis|Writing of the manuscript	Writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
4894944	27347252	RF	1	Study design|Data analysis|Writing of the manuscript	Study design	Conceived and designed the experiments	Methodology	YES
4894944	27347252	RF	1	Study design|Data analysis|Writing of the manuscript	Data analysis	Analyzed the data	Formal analysis	YES
4894944	27347252	RF	1	Study design|Data analysis|Writing of the manuscript	Writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5093977	27806686	EX	2	designed the study|designed the pipeline|wrote the python script|designed and implemented the method for determination of potential rd markers|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5093977	27806686	EX	2	designed the study|designed the pipeline|wrote the python script|designed and implemented the method for determination of potential rd markers|wrote the manuscript	designed the pipeline	Conceived and designed the experiments	-	YES
5093977	27806686	EX	2	designed the study|designed the pipeline|wrote the python script|designed and implemented the method for determination of potential rd markers|wrote the manuscript	wrote the python script	Contributed reagents/materials/analysis tools|Wrote the paper	Software|Writing - Original Draft	YES
5093977	27806686	EX	2	designed the study|designed the pipeline|wrote the python script|designed and implemented the method for determination of potential rd markers|wrote the manuscript	designed and implemented the method for determination of potential rd markers	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5093977	27806686	EX	2	designed the study|designed the pipeline|wrote the python script|designed and implemented the method for determination of potential rd markers|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5093977	27806686	KF	2	designed the study|prepared the rd and lus sequences and designed the decision rule for prediction|designed the pipeline|wrote the manuscript|edited the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5093977	27806686	KF	2	designed the study|prepared the rd and lus sequences and designed the decision rule for prediction|designed the pipeline|wrote the manuscript|edited the manuscript	prepared the rd and lus sequences and designed the decision rule for prediction	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5093977	27806686	KF	2	designed the study|prepared the rd and lus sequences and designed the decision rule for prediction|designed the pipeline|wrote the manuscript|edited the manuscript	designed the pipeline	Conceived and designed the experiments	-	YES
5093977	27806686	KF	2	designed the study|prepared the rd and lus sequences and designed the decision rule for prediction|designed the pipeline|wrote the manuscript|edited the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5093977	27806686	KF	2	designed the study|prepared the rd and lus sequences and designed the decision rule for prediction|designed the pipeline|wrote the manuscript|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5093977	27806686	RTH	2	designed the study|edited the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5093977	27806686	RTH	2	designed the study|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5093977	27806686	TYY	2	coordinated the study	coordinated the study	-	Project administration	YES
5466143	28649257	AA	2	participated in the insect feeding assays	participated in the insect feeding assays	Performed the experiments	Investigation	YES
5466143	28649257	All authors	2	contributed to final version of the manuscript	contributed to final version of the manuscript	-	-	NO
5466143	28649257	FO	2	participated in the insect feeding assays	participated in the insect feeding assays	Performed the experiments	Investigation	YES
5466143	28649257	ID	2	conceived the research|participated in the design, the acquisition, analysis, or interpretation of data for the work	conceived the research	Conceived and designed the experiments	Conceptualization	YES
5466143	28649257	ID	2	conceived the research|participated in the design, the acquisition, analysis, or interpretation of data for the work	participated in the design, the acquisition, analysis, or interpretation of data for the work	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5466143	28649257	MM	2	conceived the research|participated in the design, the acquisition, analysis, or interpretation of data for the work	conceived the research	Conceived and designed the experiments	Conceptualization	YES
5466143	28649257	MM	2	conceived the research|participated in the design, the acquisition, analysis, or interpretation of data for the work	participated in the design, the acquisition, analysis, or interpretation of data for the work	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5466143	28649257	MS	2	performed most of the experimental research|participated in the design, the acquisition, analysis, or interpretation of data for the work	performed most of the experimental research	Performed the experiments	Investigation	YES
5466143	28649257	MS	2	performed most of the experimental research|participated in the design, the acquisition, analysis, or interpretation of data for the work	participated in the design, the acquisition, analysis, or interpretation of data for the work	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5466143	28649257	VG	2	conceived the research|participated in the design, the acquisition, analysis, or interpretation of data for the work	conceived the research	Conceived and designed the experiments	Conceptualization	YES
5466143	28649257	VG	2	conceived the research|participated in the design, the acquisition, analysis, or interpretation of data for the work	participated in the design, the acquisition, analysis, or interpretation of data for the work	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3974166	24695243	AA	PLoS52	designed the study|organized and supported data collection|analysed the data|drafted the initial manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
3974166	24695243	AA	PLoS52	designed the study|organized and supported data collection|analysed the data|drafted the initial manuscript	organized and supported data collection	Performed the experiments	Investigation	YES
3974166	24695243	AA	PLoS52	designed the study|organized and supported data collection|analysed the data|drafted the initial manuscript	analysed the data	Analyzed the data	Formal analysis	YES
3974166	24695243	AA	PLoS52	designed the study|organized and supported data collection|analysed the data|drafted the initial manuscript	drafted the initial manuscript	Wrote the paper	Writing - Original Draft	YES
3974166	24695243	CS	PLoS52	analysed the data|critically reviewed the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
3974166	24695243	CS	PLoS52	analysed the data|critically reviewed the manuscript	critically reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
3974166	24695243	MGW	PLoS52	designed the study|critically reviewed the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
3974166	24695243	MGW	PLoS52	designed the study|critically reviewed the manuscript	critically reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
3974166	24695243	ML	PLoS52	organized and supported data collection	organized and supported data collection	Performed the experiments	Investigation	YES
4400131	25880774	DA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400131	25880774	DA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400131	25880774	DA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400131	25880774	DA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400131	25880774	DA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400131	25880774	DR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400131	25880774	DR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400131	25880774	DR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400131	25880774	DR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400131	25880774	FM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400131	25880774	FM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400131	25880774	FM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400131	25880774	FM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2042983	17850671	AM	2	had responsibility for oversight of study operations, and participated in the drafting of the manuscript	had responsibility for oversight of study operations, and participated in the drafting of the manuscript	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Original Draft	YES
2042983	17850671	EM	2	contributed to the development of the study methods, was responsible for overseeing the collection of data in the michigan site, and participated in drafting of the manuscript	contributed to the development of the study methods, was responsible for overseeing the collection of data in the michigan site, and participated in drafting of the manuscript	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Methodology|Resources|Supervision|Writing - Original Draft	YES
2042983	17850671	MD	2	had responsibility for data management and for the analysis of the data, and participated in drafting the manuscript	had responsibility for data management and for the analysis of the data, and participated in drafting the manuscript	Analyzed the data|Wrote the paper	Data curation|Formal analysis|Writing - Original Draft	YES
2042983	17850671	PS	2	had primary responsibility for design of the study, for developing the analysis concept, and for writing the manuscript	had primary responsibility for design of the study, for developing the analysis concept, and for writing the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
2042983	17850671	SEB	2	contributed to the development of the study methods, was responsible for overseeing the collection of data in the king county site, and participated in drafting of the manuscript	contributed to the development of the study methods, was responsible for overseeing the collection of data in the king county site, and participated in drafting of the manuscript	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Methodology|Resources|Supervision|Writing - Original Draft	YES
2042983	17850671	STB	2	contributed to the development of the study methods, was responsible for overseeing the collection of data in the louisiana site, and participated in drafting of the manuscript	contributed to the development of the study methods, was responsible for overseeing the collection of data in the louisiana site, and participated in drafting of the manuscript	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Methodology|Resources|Supervision|Writing - Original Draft	YES
5466985	28659931	MM	2	work leader	work leader	-	Supervision	YES
5093994	27806688	FY	2	planned the work|supervised the study and revised the manuscript	planned the work	Conceived and designed the experiments	Conceptualization	YES
5093994	27806688	FY	2	planned the work|supervised the study and revised the manuscript	supervised the study and revised the manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
5093994	27806688	GJ	2	implemented the web version of the pipeline	implemented the web version of the pipeline	Performed the experiments	Investigation	YES
5093994	27806688	JX	2	provided insights and revised the manuscript	provided insights and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5093994	27806688	PL	2	carried out the research, command line pipeline implementation, web user interface design, and drafted the manuscript	carried out the research, command line pipeline implementation, web user interface design, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Software|Writing - Original Draft	YES
5093994	27806688	SC	2	planned the work|revised the manuscript	planned the work	Conceived and designed the experiments	Conceptualization	YES
5093994	27806688	SC	2	planned the work|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5093994	27806688	XQ	2	implemented the web version of the pipeline	implemented the web version of the pipeline	Performed the experiments	Investigation	YES
3976531	24702797	FB	2	conceived, designed and performed the experiments	conceived, designed and performed the experiments	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
4400132	25880634	DH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400132	25880634	DH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400132	25880634	DH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400132	25880634	DH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400132	25880634	EM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Applied and obtained rwandan ethical approvals	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400132	25880634	EM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Applied and obtained rwandan ethical approvals	Performed the experiments	Performed the experiments	Investigation	YES
4400132	25880634	EM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Applied and obtained rwandan ethical approvals	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400132	25880634	EM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Applied and obtained rwandan ethical approvals	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400132	25880634	EM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Applied and obtained rwandan ethical approvals	Applied and obtained rwandan ethical approvals	-	Project administration	YES
4400132	25880634	JCD	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400132	25880634	JDS	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400132	25880634	KA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Applied and obtained rwandan ethical approvals	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400132	25880634	KA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Applied and obtained rwandan ethical approvals	Performed the experiments	Performed the experiments	Investigation	YES
4400132	25880634	KA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Applied and obtained rwandan ethical approvals	Analyzed the data	Analyzed the data	Formal analysis	YES
4400132	25880634	KA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Applied and obtained rwandan ethical approvals	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400132	25880634	KA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Applied and obtained rwandan ethical approvals	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400132	25880634	KA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Applied and obtained rwandan ethical approvals	Applied and obtained rwandan ethical approvals	-	Project administration	YES
4400132	25880634	MC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Applied and obtained rwandan ethical approvals	Performed the experiments	Performed the experiments	Investigation	YES
4400132	25880634	MC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Applied and obtained rwandan ethical approvals	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400132	25880634	MC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Applied and obtained rwandan ethical approvals	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400132	25880634	MC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Applied and obtained rwandan ethical approvals	Applied and obtained rwandan ethical approvals	-	Project administration	YES
4400132	25880634	QS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400132	25880634	QS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400132	25880634	QS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400132	25880634	QS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5466986	28659945	AAD	PLoS52	revised the paper critically	revised the paper critically	Wrote the paper	Writing - Review & Editing	YES
5466986	28659945	AH	PLoS52	revised the paper critically	revised the paper critically	Wrote the paper	Writing - Review & Editing	YES
5466986	28659945	AP	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5466986	28659945	All authors	PLoS52	revised and approved the final manuscript	revised and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5466986	28659945	DF	PLoS52	revised the paper critically	revised the paper critically	Wrote the paper	Writing - Review & Editing	YES
5466986	28659945	DM	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5466986	28659945	EG	PLoS52	conceptualized and wrote the manuscript	conceptualized and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5466986	28659945	JT	PLoS52	revised the paper critically	revised the paper critically	Wrote the paper	Writing - Review & Editing	YES
5466986	28659945	MI	PLoS52	revised the paper critically	revised the paper critically	Wrote the paper	Writing - Review & Editing	YES
5466986	28659945	MR	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5466986	28659945	MS	PLoS52	revised the paper critically	revised the paper critically	Wrote the paper	Writing - Review & Editing	YES
5466986	28659945	RB	PLoS52	revised the paper critically	revised the paper critically	Wrote the paper	Writing - Review & Editing	YES
5466986	28659945	SO	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5466986	28659945	TG-H	PLoS52	conceptualized and wrote the manuscript|performed the experiments	conceptualized and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5466986	28659945	TG-H	PLoS52	conceptualized and wrote the manuscript|performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5466986	28659945	WB	PLoS52	revised the paper critically	revised the paper critically	Wrote the paper	Writing - Review & Editing	YES
2075499	17877798	All authors	2	had equal responsibility for the decision to submit for publication	had equal responsibility for the decision to submit for publication	-	-	NO
5094011	27809783	AD	1	Contributed data|Performed data analysis	Contributed data	Contributed reagents/materials/analysis tools	Resources	YES
5094011	27809783	AD	1	Contributed data|Performed data analysis	Performed data analysis	Analyzed the data	Formal analysis	YES
5094011	27809783	BM	1	Participated in the design of the study|Contributed data	Participated in the design of the study	Conceived and designed the experiments	Methodology	YES
5094011	27809783	BM	1	Participated in the design of the study|Contributed data	Contributed data	Contributed reagents/materials/analysis tools	Resources	YES
5094011	27809783	CM	1	Contributed data|Performed data analysis	Contributed data	Contributed reagents/materials/analysis tools	Resources	YES
5094011	27809783	CM	1	Contributed data|Performed data analysis	Performed data analysis	Analyzed the data	Formal analysis	YES
5094011	27809783	DD	1	Performed data analysis	Performed data analysis	Analyzed the data	Formal analysis	YES
5094011	27809783	GM	1	Contributed data	Contributed data	Contributed reagents/materials/analysis tools	Resources	YES
5094011	27809783	KM	1	Contributed data|Performed data analysis	Contributed data	Contributed reagents/materials/analysis tools	Resources	YES
5094011	27809783	KM	1	Contributed data|Performed data analysis	Performed data analysis	Analyzed the data	Formal analysis	YES
5094011	27809783	LH	1	Contributed data	Contributed data	Contributed reagents/materials/analysis tools	Resources	YES
5094011	27809783	LP	1	Contributed data|Performed data analysis	Contributed data	Contributed reagents/materials/analysis tools	Resources	YES
5094011	27809783	LP	1	Contributed data|Performed data analysis	Performed data analysis	Analyzed the data	Formal analysis	YES
5094011	27809783	LV	1	Performed data analysis	Performed data analysis	Analyzed the data	Formal analysis	YES
5094011	27809783	MP	1	Contributed data|Performed data analysis	Contributed data	Contributed reagents/materials/analysis tools	Resources	YES
5094011	27809783	MP	1	Contributed data|Performed data analysis	Performed data analysis	Analyzed the data	Formal analysis	YES
5094011	27809783	ON	1	Participated in the design of the study|Contributed data	Participated in the design of the study	Conceived and designed the experiments	Methodology	YES
5094011	27809783	ON	1	Participated in the design of the study|Contributed data	Contributed data	Contributed reagents/materials/analysis tools	Resources	YES
5094011	27809783	PH	1	Contributed data	Contributed data	Contributed reagents/materials/analysis tools	Resources	YES
5094011	27809783	RSP	1	Contributed data	Contributed data	Contributed reagents/materials/analysis tools	Resources	YES
5094011	27809783	SL	1	Contributed data	Contributed data	Contributed reagents/materials/analysis tools	Resources	YES
5094011	27809783	TP	1	Participated in the design of the study|Performed data analysis	Participated in the design of the study	Conceived and designed the experiments	Methodology	YES
5094011	27809783	TP	1	Participated in the design of the study|Performed data analysis	Performed data analysis	Analyzed the data	Formal analysis	YES
5094011	27809783	TW	1	Contributed data	Contributed data	Contributed reagents/materials/analysis tools	Resources	YES
5094011	27809783	XZ	1	Contributed data	Contributed data	Contributed reagents/materials/analysis tools	Resources	YES
3980465	24713375	All authors	2	contributed to interpretation of the data	contributed to interpretation of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
3980465	24713375	CL	2	developed the protocol, to which all authors then contributed|developed the analysis plan and performed statistical analyses|wrote the report, to which all authors then contributed	developed the protocol, to which all authors then contributed	Conceived and designed the experiments	Methodology	YES
3980465	24713375	CL	2	developed the protocol, to which all authors then contributed|developed the analysis plan and performed statistical analyses|wrote the report, to which all authors then contributed	developed the analysis plan and performed statistical analyses	Analyzed the data	Formal analysis	YES
3980465	24713375	CL	2	developed the protocol, to which all authors then contributed|developed the analysis plan and performed statistical analyses|wrote the report, to which all authors then contributed	wrote the report, to which all authors then contributed	Wrote the paper	Writing - Original Draft	YES
3980465	24713375	FD	2	edited the final version of the manuscript	edited the final version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
3980465	24713375	JD	2	developed the protocol, to which all authors then contributed	developed the protocol, to which all authors then contributed	Conceived and designed the experiments	Methodology	YES
3980465	24713375	SE	2	developed the protocol, to which all authors then contributed	developed the protocol, to which all authors then contributed	Conceived and designed the experiments	Methodology	YES
4400134	25880483	AMBM	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400134	25880483	AMBM	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400134	25880483	BLH	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400134	25880483	BLH	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400134	25880483	DPG	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400134	25880483	DPG	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400134	25880483	FCB	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400134	25880483	FCB	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400134	25880483	FCW	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400134	25880483	FCW	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400134	25880483	FCW	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400134	25880483	HG	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400134	25880483	HG	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400134	25880483	JMM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400134	25880483	JMM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400134	25880483	JMM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400134	25880483	LCM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400134	25880483	LCM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400134	25880483	LCM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400134	25880483	LCM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400134	25880483	LCM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400134	25880483	MCFA	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400134	25880483	MCFA	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400134	25880483	MRD	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400134	25880483	MRD	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5466987	28659932	AA	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5466987	28659932	HE	2	designed the experiment|performed experiments	designed the experiment	Conceived and designed the experiments	Methodology	YES
5466987	28659932	HE	2	designed the experiment|performed experiments	performed experiments	Performed the experiments	Investigation	YES
5466987	28659932	KY	2	designed the experiment	designed the experiment	Conceived and designed the experiments	Methodology	YES
5466987	28659932	ME	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5466987	28659932	all authors	2	contributed in validating, writing, and approving the final version of the manuscript	contributed in validating, writing, and approving the final version of the manuscript	Performed the experiments|Wrote the paper	Validation|Writing - Original Draft	YES
3983475	24721464	CDR	2	contributed to the interpretation of the data, and critically reviewed and provided substantial input to the intellectual content of the manuscript	contributed to the interpretation of the data, and critically reviewed and provided substantial input to the intellectual content of the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
3983475	24721464	JAD	2	conceived the study concept and design, provided overall oversight and revised the manuscript	conceived the study concept and design, provided overall oversight and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Supervision|Writing - Review & Editing	YES
3983475	24721464	LAM	2	conceived the study concept and design, provided overall oversight and revised the manuscript	conceived the study concept and design, provided overall oversight and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Supervision|Writing - Review & Editing	YES
3983475	24721464	LS	2	contributed to data acquisition and drafting of the manuscript	contributed to data acquisition and drafting of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3983475	24721464	MS	2	contributed to data acquisition and drafting of the manuscript	contributed to data acquisition and drafting of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3983475	24721464	NC	2	contributed to the study concept and design, analysed the data and prepared the first draft of the manuscript	contributed to the study concept and design, analysed the data and prepared the first draft of the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Methodology|Resources|Writing - Original Draft	YES
3983475	24721464	NR	2	contributed to data acquisition and drafting of the manuscript	contributed to data acquisition and drafting of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3983475	24721464	TT	2	conceived the study concept and design, provided overall oversight and revised the manuscript	conceived the study concept and design, provided overall oversight and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Supervision|Writing - Review & Editing	YES
5094014	27806696	AB	2	involved in the coordination and implementation of the study and helped draft the manuscript	involved in the coordination and implementation of the study and helped draft the manuscript	Performed the experiments|Wrote the paper	Investigation|Project administration|Writing - Original Draft	YES
5094014	27806696	AM	2	helped in microarray data analysis and network construction and drafted the manuscript	helped in microarray data analysis and network construction and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5094014	27806696	ANJ	2	involved in the coordination and implementation of the study and helped draft the manuscript	involved in the coordination and implementation of the study and helped draft the manuscript	Performed the experiments|Wrote the paper	Investigation|Project administration|Writing - Original Draft	YES
5094014	27806696	HB	2	carried out the analyses and drafted the manuscript	carried out the analyses and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5094014	27806696	JMR	2	conceived the analyses, processed the data, involved in the coordination and implementation of the study, and drafted the manuscript	conceived the analyses, processed the data, involved in the coordination and implementation of the study, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Data curation|Formal analysis|Investigation|Project administration|Writing - Original Draft	YES
5094014	27806696	ZLH	2	helped in database design and development	helped in database design and development	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
2089066	17900337	BF	2	worked on the original draft of the protocol, informed consent forms and study instruments as the first coordinator of this study at the population council|advised on the qualitative data analysis for the study, and contributed editorial comments on several versions of this paper	worked on the original draft of the protocol, informed consent forms and study instruments as the first coordinator of this study at the population council	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft	YES
2089066	17900337	BF	2	worked on the original draft of the protocol, informed consent forms and study instruments as the first coordinator of this study at the population council|advised on the qualitative data analysis for the study, and contributed editorial comments on several versions of this paper	advised on the qualitative data analysis for the study, and contributed editorial comments on several versions of this paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
2089066	17900337	GR	2	was the principle investigator at the mrc for the study and worked with the population council to develop the protocol and systems for study implementation|wrote the paper following data analysis	was the principle investigator at the mrc for the study and worked with the population council to develop the protocol and systems for study implementation	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
2089066	17900337	GR	2	was the principle investigator at the mrc for the study and worked with the population council to develop the protocol and systems for study implementation|wrote the paper following data analysis	wrote the paper following data analysis	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
2089066	17900337	HJ	2	was the data manager for this study at the population council, and worked on data analysis|contributed editorial comments on several versions of this paper	was the data manager for this study at the population council, and worked on data analysis	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Project administration	YES
2089066	17900337	HJ	2	was the data manager for this study at the population council, and worked on data analysis|contributed editorial comments on several versions of this paper	contributed editorial comments on several versions of this paper	Wrote the paper	Writing - Review & Editing	YES
2089066	17900337	JvdW	2	was the principle investigator of this study at the population council|developed the original protocol and study instruments	was the principle investigator of this study at the population council	-	-	NO
2089066	17900337	JvdW	2	was the principle investigator of this study at the population council|developed the original protocol and study instruments	developed the original protocol and study instruments	Conceived and designed the experiments	Methodology	YES
2089066	17900337	SB	2	was the coordinator of this study at the population council	was the coordinator of this study at the population council	-	Project administration	YES
4400136	25880807	AMD	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400136	25880807	AMD	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400136	25880807	AMD	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400136	25880807	JTB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400136	25880807	JTB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400136	25880807	JTB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400136	25880807	JTB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400136	25880807	JTB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5466989	28659955	CL	2	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5466989	28659955	HW	2	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5466989	28659955	JX	2	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5466989	28659955	MW	2	contributed to the experimental design|performed the experiments and analyzed the data	contributed to the experimental design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5466989	28659955	MW	2	contributed to the experimental design|performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5466989	28659955	YW	2	contributed to the experimental design|performed the experiments and analyzed the data	contributed to the experimental design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5466989	28659955	YW	2	contributed to the experimental design|performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5466989	28659955	ZW	2	contributed to the experimental design|revised it	contributed to the experimental design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5466989	28659955	ZW	2	contributed to the experimental design|revised it	revised it	Wrote the paper	Writing - Review & Editing	YES
3991830	24746179	AB	2	provided input into the study protocol and revised the manuscript for important intellectual content	provided input into the study protocol and revised the manuscript for important intellectual content	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
3991830	24746179	AK	2	provided input into the study protocol and revised the manuscript for important intellectual content	provided input into the study protocol and revised the manuscript for important intellectual content	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
3991830	24746179	HB	2	conceptualized and designed the study protocol, collected and analysed all data and was the primary author of the manuscript	conceptualized and designed the study protocol, collected and analysed all data and was the primary author of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
3991830	24746179	HBs	2	thesis committee, provided ongoing scientific input and mentorship throughout the study and revised the manuscript for important intellectual content	thesis committee, provided ongoing scientific input and mentorship throughout the study and revised the manuscript for important intellectual content	Wrote the paper	Supervision|Writing - Review & Editing	YES
3991830	24746179	JR	2	provided input into the study protocol and revised the manuscript for important intellectual content	provided input into the study protocol and revised the manuscript for important intellectual content	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5094019	27806699	All authors	2	read, contributed to, and approved the final manuscript	read, contributed to, and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5094019	27806699	CF	2	conducted histopathological examinations of kidney and muscle tissues	conducted histopathological examinations of kidney and muscle tissues	Performed the experiments	Investigation	YES
5094019	27806699	JCB	2	participated in fish challenge and maintenance, sample collection, performed rna extractions, reverse transcription, and viral rt qpcr diagnostic screening	participated in fish challenge and maintenance, sample collection, performed rna extractions, reverse transcription, and viral rt qpcr diagnostic screening	Performed the experiments	Investigation	YES
5094019	27806699	JR	2	aided with dissections, injections, and fish care	aided with dissections, injections, and fish care	Performed the experiments	Investigation	YES
5094019	27806699	KAG	2	conceived the study, participated in its design, and aided in the collection of samples	conceived the study, participated in its design, and aided in the collection of samples	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
5094019	27806699	MLR	2	conceived the study, participated in its design, and aided in the collection of samples	conceived the study, participated in its design, and aided in the collection of samples	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
5094019	27806699	MPP	2	participated in study design, carried out data interpretation, performed differential expression and qpcr analyses, and drafted the manuscript	participated in study design, carried out data interpretation, performed differential expression and qpcr analyses, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5094019	27806699	SCJ	2	conceived the study, participated in its design, and aided in the collection of samples	conceived the study, participated in its design, and aided in the collection of samples	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
5094019	27806699	SMI	2	performed qpcr expression validation on early time point samples	performed qpcr expression validation on early time point samples	Performed the experiments	Investigation|Validation	YES
5094019	27806699	TTP	2	conducted histopathological examinations of kidney and muscle tissues	conducted histopathological examinations of kidney and muscle tissues	Performed the experiments	Investigation	YES
5466992	28659939	GE	2	have conceived and designed the paper|have analyzed the data|have contributed with reagents/materials/analysis tools|have written the paper	have conceived and designed the paper	Conceived and designed the experiments	Conceptualization	YES
5466992	28659939	GE	2	have conceived and designed the paper|have analyzed the data|have contributed with reagents/materials/analysis tools|have written the paper	have analyzed the data	Analyzed the data	Formal analysis	YES
5466992	28659939	GE	2	have conceived and designed the paper|have analyzed the data|have contributed with reagents/materials/analysis tools|have written the paper	have contributed with reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5466992	28659939	GE	2	have conceived and designed the paper|have analyzed the data|have contributed with reagents/materials/analysis tools|have written the paper	have written the paper	Wrote the paper	Writing - Original Draft	YES
5466992	28659939	JDASJ	2	have conceived and designed the paper|have performed the experiments|have analyzed the data|have written the paper	have conceived and designed the paper	Conceived and designed the experiments	Conceptualization	YES
5466992	28659939	JDASJ	2	have conceived and designed the paper|have performed the experiments|have analyzed the data|have written the paper	have performed the experiments	Performed the experiments	Investigation	YES
5466992	28659939	JDASJ	2	have conceived and designed the paper|have performed the experiments|have analyzed the data|have written the paper	have analyzed the data	Analyzed the data	Formal analysis	YES
5466992	28659939	JDASJ	2	have conceived and designed the paper|have performed the experiments|have analyzed the data|have written the paper	have written the paper	Wrote the paper	Writing - Original Draft	YES
5466992	28659939	JdA	2	have conceived and designed the paper|have analyzed the data|have contributed with reagents/materials/analysis tools|have written the paper	have conceived and designed the paper	Conceived and designed the experiments	Conceptualization	YES
5466992	28659939	JdA	2	have conceived and designed the paper|have analyzed the data|have contributed with reagents/materials/analysis tools|have written the paper	have analyzed the data	Analyzed the data	Formal analysis	YES
5466992	28659939	JdA	2	have conceived and designed the paper|have analyzed the data|have contributed with reagents/materials/analysis tools|have written the paper	have contributed with reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5466992	28659939	JdA	2	have conceived and designed the paper|have analyzed the data|have contributed with reagents/materials/analysis tools|have written the paper	have written the paper	Wrote the paper	Writing - Original Draft	YES
5466992	28659939	OP	2	have conceived and designed the paper|have performed the experiments|have analyzed the data	have conceived and designed the paper	Conceived and designed the experiments	Conceptualization	YES
5466992	28659939	OP	2	have conceived and designed the paper|have performed the experiments|have analyzed the data	have performed the experiments	Performed the experiments	Investigation	YES
5466992	28659939	OP	2	have conceived and designed the paper|have performed the experiments|have analyzed the data	have analyzed the data	Analyzed the data	Formal analysis	YES
5466992	28659939	RC	2	have performed the experiments|have analyzed the data	have performed the experiments	Performed the experiments	Investigation	YES
5466992	28659939	RC	2	have performed the experiments|have analyzed the data	have analyzed the data	Analyzed the data	Formal analysis	YES
2147021	17937821	All five authors	PLoS52	drafted and approved this version of the manuscript	drafted and approved this version of the manuscript	Wrote the paper	Writing - Original Draft	YES
2147021	17937821	CMLK	PLoS52	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
2147021	17937821	JJG	PLoS52	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
2147021	17937821	PK	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
2147021	17937821	XL	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
2147021	17937821	YJ	PLoS52	designed the study|analyzed the data	designed the study	Conceived and designed the experiments	Methodology	YES
2147021	17937821	YJ	PLoS52	designed the study|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
4400137	25881125	IH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400137	25881125	IH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400137	25881125	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400137	25881125	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400137	25881125	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400137	25881125	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400137	25881125	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400137	25881125	MT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400137	25881125	MT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400137	25881125	MT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400137	25881125	MT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400137	25881125	MT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3991831	24746180	AU	2	performed the sequencing and phylogenetic analyses	performed the sequencing and phylogenetic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3991831	24746180	KM	2	collected patient data and prepared the manuscript	collected patient data and prepared the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3991831	24746180	MLP	2	collected patient data and prepared the manuscript	collected patient data and prepared the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3991831	24746180	MP	2	designed the study, analysed the data, performed statistics and phylogenetic analyses and wrote the manuscript	designed the study, analysed the data, performed statistics and phylogenetic analyses and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
3991831	24746180	MWJ	2	collected patient data and prepared the manuscript	collected patient data and prepared the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4400139	25881289	HCM	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400139	25881289	JC	PLoS5	Coordinated the record linkage	Coordinated the record linkage	-	Project administration	YES
4400139	25881289	JEN	PLoS5	Proposed the design of the follow-up study	Proposed the design of the follow-up study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400139	25881289	RW	PLoS5	Coordinated the record linkage	Coordinated the record linkage	-	Project administration	YES
5094043	27809761	BJH	2	oversaw the research	oversaw the research	-	Supervision	YES
5094043	27809761	PVM	2	oversaw the research	oversaw the research	-	Supervision	YES
5466993	28659935	JH	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5466993	28659935	JN	PLoS52	conceived and designed the experiments|analyzed the data|wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5466993	28659935	JN	PLoS52	conceived and designed the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5466993	28659935	JN	PLoS52	conceived and designed the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5466993	28659935	LD	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5466993	28659935	MX	PLoS52	conceived and designed the experiments|analyzed the data	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5466993	28659935	MX	PLoS52	conceived and designed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5466993	28659935	WX	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5466993	28659935	XY	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5466993	28659935	XZ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5466993	28659935	ZJ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5466993	28659935	ZS	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5466993	28659935	ZW	PLoS52	analyzed the data|contributed reagents/materials/analytical tools	analyzed the data	Analyzed the data	Formal analysis	YES
5466993	28659935	ZW	PLoS52	analyzed the data|contributed reagents/materials/analytical tools	contributed reagents/materials/analytical tools	Contributed reagents/materials/analysis tools	Resources	YES
2174928	17939856	AH	2	designed the study, interpreted the data and reviewed the manuscript	designed the study, interpreted the data and reviewed the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
2174928	17939856	CHH	2	participated in data collection, laboratory testing, interpreted the data and reviewed the manuscript	participated in data collection, laboratory testing, interpreted the data and reviewed the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
2174928	17939856	EJM	2	conceived the study, coordinated data collection and analysis, interpreted the results and drafted the manuscript	conceived the study, coordinated data collection and analysis, interpreted the results and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Project administration|Writing - Original Draft	YES
2174928	17939856	EK	2	participated in data collection, laboratory testing, interpreted the data and reviewed the manuscript	participated in data collection, laboratory testing, interpreted the data and reviewed the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
2174928	17939856	GHL	2	designed the study, collected the data, analyzed and interpreted the data and reviewed the manuscript	designed the study, collected the data, analyzed and interpreted the data and reviewed the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Review & Editing	YES
2174928	17939856	KIK	2	coordinated the design and protocol, analyzed and interpreted the data and reviewed the manuscript	coordinated the design and protocol, analyzed and interpreted the data and reviewed the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Project administration|Writing - Review & Editing	YES
2174928	17939856	KSM	2	participated in data collection, laboratory testing, interpreted the data and reviewed the manuscript	participated in data collection, laboratory testing, interpreted the data and reviewed the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
2174928	17939856	NES	2	participated in data collection, laboratory testing, interpreted the data and reviewed the manuscript	participated in data collection, laboratory testing, interpreted the data and reviewed the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
3999943	24763078	CL	2	contributed to the study design|contributed to critical revision of the manuscript for important intellectual content	contributed to the study design	Conceived and designed the experiments	Methodology	YES
3999943	24763078	CL	2	contributed to the study design|contributed to critical revision of the manuscript for important intellectual content	contributed to critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
3999943	24763078	DY	2	provided data from their health facilities	provided data from their health facilities	Contributed reagents/materials/analysis tools	Resources	YES
3999943	24763078	FD	2	managed the study and data collected the data|contributed to the study design|provided data from their health facilities|contributed to critical revision of the manuscript for important intellectual content	managed the study and data collected the data	Performed the experiments|Analyzed the data	Data curation|Investigation|Project administration	YES
3999943	24763078	FD	2	managed the study and data collected the data|contributed to the study design|provided data from their health facilities|contributed to critical revision of the manuscript for important intellectual content	contributed to the study design	Conceived and designed the experiments	Methodology	YES
3999943	24763078	FD	2	managed the study and data collected the data|contributed to the study design|provided data from their health facilities|contributed to critical revision of the manuscript for important intellectual content	provided data from their health facilities	Contributed reagents/materials/analysis tools	Resources	YES
3999943	24763078	FD	2	managed the study and data collected the data|contributed to the study design|provided data from their health facilities|contributed to critical revision of the manuscript for important intellectual content	contributed to critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
3999943	24763078	FK	2	provided data from their health facilities	provided data from their health facilities	Contributed reagents/materials/analysis tools	Resources	YES
3999943	24763078	HDM	2	provided data from their health facilities	provided data from their health facilities	Contributed reagents/materials/analysis tools	Resources	YES
3999943	24763078	HSS	2	provided data from their health facilities	provided data from their health facilities	Contributed reagents/materials/analysis tools	Resources	YES
3999943	24763078	JA	2	provided data from their health facilities	provided data from their health facilities	Contributed reagents/materials/analysis tools	Resources	YES
3999943	24763078	LR	2	provided data from their health facilities	provided data from their health facilities	Contributed reagents/materials/analysis tools	Resources	YES
3999943	24763078	NB	2	provided data from their health facilities	provided data from their health facilities	Contributed reagents/materials/analysis tools	Resources	YES
3999943	24763078	NK	2	provided data from their health facilities	provided data from their health facilities	Contributed reagents/materials/analysis tools	Resources	YES
3999943	24763078	SD	2	performed statistical analyses and wrote the manuscript|contributed to critical revision of the manuscript for important intellectual content	performed statistical analyses and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3999943	24763078	SD	2	performed statistical analyses and wrote the manuscript|contributed to critical revision of the manuscript for important intellectual content	contributed to critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
3999943	24763078	SK	2	provided data from their health facilities	provided data from their health facilities	Contributed reagents/materials/analysis tools	Resources	YES
3999943	24763078	VL	2	contributed to the study design|contributed to critical revision of the manuscript for important intellectual content	contributed to the study design	Conceived and designed the experiments	Methodology	YES
3999943	24763078	VL	2	contributed to the study design|contributed to critical revision of the manuscript for important intellectual content	contributed to critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4400140	25879532	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400140	25879532	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4400140	25879532	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4400140	25879532	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400140	25879532	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400140	25879532	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400140	25879532	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400140	25879532	CC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4400140	25879532	CC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400140	25879532	DG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400140	25879532	DG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400140	25879532	DG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400140	25879532	FM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400140	25879532	FM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400140	25879532	FM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400140	25879532	FM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400140	25879532	FNL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400140	25879532	MT	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4400140	25879532	SED	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400140	25879532	SED	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400140	25879532	SED	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400140	25879532	SED	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400140	25879532	VC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400140	25879532	VC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4400140	25879532	VC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400140	25879532	VV	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5466995	28659937	NSK	2	conducted the research experiments as part of his msc thesis, he contributed to the data analyses and to drafting the manuscript	conducted the research experiments as part of his msc thesis, he contributed to the data analyses and to drafting the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5466995	28659937	SB	2	was the principal investigator of this research project, supervised nsk, contributed to data analyses and the drafting of the manuscript	was the principal investigator of this research project, supervised nsk, contributed to data analyses and the drafting of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Funding acquisition|Supervision|Writing - Original Draft	YES
2211285	17941994	PPJ	2	participated in the design of and created the retroviral vectors	participated in the design of and created the retroviral vectors	Conceived and designed the experiments	-	YES
2211285	17941994	RPJ	2	participated in the design of the vectors and the subsequent study, and edited the manuscript	participated in the design of the vectors and the subsequent study, and edited the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
2211285	17941994	SEB	2	participated in the design of the vectors and the subsequent study, coordinated the study, performed the sequence alignment, matched the consensus sequences and wrote the manuscript	participated in the design of the vectors and the subsequent study, coordinated the study, performed the sequence alignment, matched the consensus sequences and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Project administration|Writing - Original Draft	YES
2211285	17941994	VRP	2	participated in the design of the vectors and the subsequent study	participated in the design of the vectors and the subsequent study	Conceived and designed the experiments	Methodology	YES
2211285	17941994	XS	2	performed the northern blots and quantified expression	performed the northern blots and quantified expression	Performed the experiments	Investigation	YES
4000430	24763077	AM	2	assisted with analysis and helped write drafts of the manuscript	assisted with analysis and helped write drafts of the manuscript	Wrote the paper	Writing - Original Draft	YES
4000430	24763077	CC	2	was coordinator of the study and helped write drafts of the manuscript	was coordinator of the study and helped write drafts of the manuscript	Wrote the paper	Project administration|Writing - Original Draft	YES
4000430	24763077	ER	2	assisted with analysis and helped write drafts of the manuscript	assisted with analysis and helped write drafts of the manuscript	Wrote the paper	Writing - Original Draft	YES
4000430	24763077	EZ	2	helped conceive of the study, and contributed to analysis	helped conceive of the study, and contributed to analysis	Conceived and designed the experiments	Conceptualization	YES
4000430	24763077	JHH	2	helped conceive of and plan the study, and helped write drafts of the manuscript	helped conceive of and plan the study, and helped write drafts of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4000430	24763077	MS	2	assisted with analysis and helped write drafts of the manuscript	assisted with analysis and helped write drafts of the manuscript	Wrote the paper	Writing - Original Draft	YES
4000430	24763077	PSim	2	helped conceive of and plan the study, and helped write drafts of the manuscript	helped conceive of and plan the study, and helped write drafts of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4000430	24763077	PSol	2	helped conceive of and plan the study, and helped write drafts of the manuscript	helped conceive of and plan the study, and helped write drafts of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4000430	24763077	SAN	2	was principal investigator of the study and led writing of this manuscript	was principal investigator of the study and led writing of this manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Funding acquisition|Writing - Original Draft	YES
4000430	24763077	VB	2	assisted with analysis and helped write drafts of the manuscript	assisted with analysis and helped write drafts of the manuscript	Wrote the paper	Writing - Original Draft	YES
5094076	27806689	AN	2	contributed reagents, materials, and methods for dna sequencing|contributed to data interpretation	contributed reagents, materials, and methods for dna sequencing	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5094076	27806689	AN	2	contributed reagents, materials, and methods for dna sequencing|contributed to data interpretation	contributed to data interpretation	Analyzed the data	Formal analysis	YES
5094076	27806689	BR	2	performed rna seq and follow-up data analyses|contributed to data interpretation	performed rna seq and follow-up data analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5094076	27806689	BR	2	performed rna seq and follow-up data analyses|contributed to data interpretation	contributed to data interpretation	Analyzed the data	Formal analysis	YES
5094076	27806689	IZ	2	designed and carried out the 3d organotypic skin culturing experiments|contributed reagents, materials, and methods for culturing experiments|contributed to data interpretation|having considerable input into the writing	designed and carried out the 3d organotypic skin culturing experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5094076	27806689	IZ	2	designed and carried out the 3d organotypic skin culturing experiments|contributed reagents, materials, and methods for culturing experiments|contributed to data interpretation|having considerable input into the writing	contributed reagents, materials, and methods for culturing experiments	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5094076	27806689	IZ	2	designed and carried out the 3d organotypic skin culturing experiments|contributed reagents, materials, and methods for culturing experiments|contributed to data interpretation|having considerable input into the writing	contributed to data interpretation	Analyzed the data	Formal analysis	YES
5094076	27806689	IZ	2	designed and carried out the 3d organotypic skin culturing experiments|contributed reagents, materials, and methods for culturing experiments|contributed to data interpretation|having considerable input into the writing	having considerable input into the writing	Wrote the paper	-	YES
5094076	27806689	JB	2	performed rna seq and follow-up data analyses|contributed to data interpretation	performed rna seq and follow-up data analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5094076	27806689	JB	2	performed rna seq and follow-up data analyses|contributed to data interpretation	contributed to data interpretation	Analyzed the data	Formal analysis	YES
5094076	27806689	PL	2	designed and carried out the 3d organotypic skin culturing experiments|contributed reagents, materials, and methods for culturing experiments|contributed to data interpretation	designed and carried out the 3d organotypic skin culturing experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5094076	27806689	PL	2	designed and carried out the 3d organotypic skin culturing experiments|contributed reagents, materials, and methods for culturing experiments|contributed to data interpretation	contributed reagents, materials, and methods for culturing experiments	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5094076	27806689	PL	2	designed and carried out the 3d organotypic skin culturing experiments|contributed reagents, materials, and methods for culturing experiments|contributed to data interpretation	contributed to data interpretation	Analyzed the data	Formal analysis	YES
5094076	27806689	RJ	2	designed and carried out the 3d organotypic skin culturing experiments|performed rna seq and follow-up data analyses|performed dna-seq and follow-up analyses|contributed to data interpretation	designed and carried out the 3d organotypic skin culturing experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5094076	27806689	RJ	2	designed and carried out the 3d organotypic skin culturing experiments|performed rna seq and follow-up data analyses|performed dna-seq and follow-up analyses|contributed to data interpretation	performed rna seq and follow-up data analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5094076	27806689	RJ	2	designed and carried out the 3d organotypic skin culturing experiments|performed rna seq and follow-up data analyses|performed dna-seq and follow-up analyses|contributed to data interpretation	performed dna-seq and follow-up analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5094076	27806689	RJ	2	designed and carried out the 3d organotypic skin culturing experiments|performed rna seq and follow-up data analyses|performed dna-seq and follow-up analyses|contributed to data interpretation	contributed to data interpretation	Analyzed the data	Formal analysis	YES
5094076	27806689	SC	2	performed rna seq and follow-up data analyses|contributed to data interpretation	performed rna seq and follow-up data analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5094076	27806689	SC	2	performed rna seq and follow-up data analyses|contributed to data interpretation	contributed to data interpretation	Analyzed the data	Formal analysis	YES
5094076	27806689	SL	2	performed dna-seq and follow-up analyses|contributed to data interpretation	performed dna-seq and follow-up analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5094076	27806689	SL	2	performed dna-seq and follow-up analyses|contributed to data interpretation	contributed to data interpretation	Analyzed the data	Formal analysis	YES
5094076	27806689	WF	2	contributed to data interpretation	contributed to data interpretation	Analyzed the data	Formal analysis	YES
3361298	22654585	I. Weig	2	participated in the study design and helped to draft the paper	participated in the study design and helped to draft the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3361298	22654585	J. Briegel	2	conceived, designed, and supervised the study	conceived, designed, and supervised the study	Conceived and designed the experiments	Conceptualization|Methodology|Supervision	YES
3361298	22654585	J. Polasek	2	designed and conducted the analysis for the years 1995-1997	designed and conducted the analysis for the years 1995-1997	Conceived and designed the experiments|Performed the experiments	Investigation	YES
3361298	22654585	P. Mohnle	2	conceived, designed, and supervised the study	conceived, designed, and supervised the study	Conceived and designed the experiments	Conceptualization|Methodology|Supervision	YES
3361298	22654585	R. Atzinger	2	designed and conducted the analysis for the years 1995-1997	designed and conducted the analysis for the years 1995-1997	Conceived and designed the experiments|Performed the experiments	Investigation	YES
3361298	22654585	U. Kreimeier	2	participated in the study design and helped to draft the paper|designed and conducted the analysis for the years 1995-1997	participated in the study design and helped to draft the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3361298	22654585	U. Kreimeier	2	participated in the study design and helped to draft the paper|designed and conducted the analysis for the years 1995-1997	designed and conducted the analysis for the years 1995-1997	Conceived and designed the experiments|Performed the experiments	Investigation	YES
3361298	22654585	V. Huge	2	participated in the study design and helped to draft the paper	participated in the study design and helped to draft the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4400141	25879446	BC	PLoS5	Performed the experiments|Analyzed the data|Conceptualized and designed the empirical data study and contributed significantly to the overall analysis|Read and approved the text	Performed the experiments	Performed the experiments	Investigation	YES
4400141	25879446	BC	PLoS5	Performed the experiments|Analyzed the data|Conceptualized and designed the empirical data study and contributed significantly to the overall analysis|Read and approved the text	Analyzed the data	Analyzed the data	Formal analysis	YES
4400141	25879446	BC	PLoS5	Performed the experiments|Analyzed the data|Conceptualized and designed the empirical data study and contributed significantly to the overall analysis|Read and approved the text	Conceptualized and designed the empirical data study and contributed significantly to the overall analysis	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
4400141	25879446	BC	PLoS5	Performed the experiments|Analyzed the data|Conceptualized and designed the empirical data study and contributed significantly to the overall analysis|Read and approved the text	Read and approved the text	-	-	NO
4400141	25879446	EK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Conducted the analysis of the empirical data, contributed conceptually and analytically to the overall paper and was the main co-author|Read and approved the text	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400141	25879446	EK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Conducted the analysis of the empirical data, contributed conceptually and analytically to the overall paper and was the main co-author|Read and approved the text	Analyzed the data	Analyzed the data	Formal analysis	YES
4400141	25879446	EK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Conducted the analysis of the empirical data, contributed conceptually and analytically to the overall paper and was the main co-author|Read and approved the text	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400141	25879446	EK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Conducted the analysis of the empirical data, contributed conceptually and analytically to the overall paper and was the main co-author|Read and approved the text	Conducted the analysis of the empirical data, contributed conceptually and analytically to the overall paper and was the main co-author	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation	YES
4400141	25879446	EK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Conducted the analysis of the empirical data, contributed conceptually and analytically to the overall paper and was the main co-author|Read and approved the text	Read and approved the text	-	-	NO
4400141	25879446	EP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Conceptualized, designed and analysed the national data study and was the lead writer|Read and approved the text	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400141	25879446	EP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Conceptualized, designed and analysed the national data study and was the lead writer|Read and approved the text	Analyzed the data	Analyzed the data	Formal analysis	YES
4400141	25879446	EP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Conceptualized, designed and analysed the national data study and was the lead writer|Read and approved the text	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400141	25879446	EP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Conceptualized, designed and analysed the national data study and was the lead writer|Read and approved the text	Conceptualized, designed and analysed the national data study and was the lead writer	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology	YES
4400141	25879446	EP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Conceptualized, designed and analysed the national data study and was the lead writer|Read and approved the text	Read and approved the text	-	-	NO
4400141	25879446	HHS	PLoS5	Analyzed the data|Wrote the paper|Contributed to data analysis of the national data and critically reviewed the paper|Read and approved the text	Analyzed the data	Analyzed the data	Formal analysis	YES
4400141	25879446	HHS	PLoS5	Analyzed the data|Wrote the paper|Contributed to data analysis of the national data and critically reviewed the paper|Read and approved the text	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400141	25879446	HHS	PLoS5	Analyzed the data|Wrote the paper|Contributed to data analysis of the national data and critically reviewed the paper|Read and approved the text	Contributed to data analysis of the national data and critically reviewed the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4400141	25879446	HHS	PLoS5	Analyzed the data|Wrote the paper|Contributed to data analysis of the national data and critically reviewed the paper|Read and approved the text	Read and approved the text	-	-	NO
4400141	25879446	NM	PLoS5	Performed the experiments|Analyzed the data|Conceptualized and designed the empirical data study and contributed significantly to the overall analysis|Read and approved the text	Performed the experiments	Performed the experiments	Investigation	YES
4400141	25879446	NM	PLoS5	Performed the experiments|Analyzed the data|Conceptualized and designed the empirical data study and contributed significantly to the overall analysis|Read and approved the text	Analyzed the data	Analyzed the data	Formal analysis	YES
4400141	25879446	NM	PLoS5	Performed the experiments|Analyzed the data|Conceptualized and designed the empirical data study and contributed significantly to the overall analysis|Read and approved the text	Conceptualized and designed the empirical data study and contributed significantly to the overall analysis	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
4400141	25879446	NM	PLoS5	Performed the experiments|Analyzed the data|Conceptualized and designed the empirical data study and contributed significantly to the overall analysis|Read and approved the text	Read and approved the text	-	-	NO
4400141	25879446	WN	PLoS5	Wrote the paper|Critically reviewed the paper|Read and approved the text	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400141	25879446	WN	PLoS5	Wrote the paper|Critically reviewed the paper|Read and approved the text	Critically reviewed the paper	Wrote the paper	Writing - Review & Editing	YES
4400141	25879446	WN	PLoS5	Wrote the paper|Critically reviewed the paper|Read and approved the text	Read and approved the text	-	-	NO
4400141	25879446	YA	PLoS5	Wrote the paper|Critically reviewed the paper|Read and approved the text	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400141	25879446	YA	PLoS5	Wrote the paper|Critically reviewed the paper|Read and approved the text	Critically reviewed the paper	Wrote the paper	Writing - Review & Editing	YES
4400141	25879446	YA	PLoS5	Wrote the paper|Critically reviewed the paper|Read and approved the text	Read and approved the text	-	-	NO
4434168	26064911	Han-Yi Xu	2	have the same contribution in this paper	have the same contribution in this paper	-	-	NO
4434168	26064911	Ju Cao	2	have the same contribution in this paper	have the same contribution in this paper	-	-	NO
4434168	26064911	Rui Tang	2	have the same contribution in this paper	have the same contribution in this paper	-	-	NO
5467002	28659946	J-FK	PLoS52	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5467002	28659946	J-YC	PLoS52	designed the research|wrote the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
5467002	28659946	J-YC	PLoS52	designed the research|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5467002	28659946	W-JL	PLoS52	designed the research|wrote the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
5467002	28659946	W-JL	PLoS52	designed the research|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5467002	28659946	WS	PLoS52	designed the research|performed the experiments|wrote the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
5467002	28659946	WS	PLoS52	designed the research|performed the experiments|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5467002	28659946	WS	PLoS52	designed the research|performed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5467002	28659946	Z-QF	PLoS52	performed the experiments|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5467002	28659946	Z-QF	PLoS52	performed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4400143	25880204	AB	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4400143	25880204	AKR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400143	25880204	AKR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400143	25880204	AKR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400143	25880204	AKR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400143	25880204	DB	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4400143	25880204	DB	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4400143	25880204	HLR	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400143	25880204	HLR	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400143	25880204	LB	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4400143	25880204	LB	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4400143	25880204	PAH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400143	25880204	PAH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400143	25880204	PAH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2211500	18031583	AA	2	participated in drafting the manuscript	participated in drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
2211500	18031583	BS	2	participated in clinical assessment of patients and drafting the manuscript	participated in clinical assessment of patients and drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
2211500	18031583	KM	2	participated in clinical assessment of study patients	participated in clinical assessment of study patients	-	-	NO
2211500	18031583	SK	2	participated in clinical assessment of patients and drafting the manuscript	participated in clinical assessment of patients and drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
2211500	18031583	SS	2	participated in the design of the study, clinical assessment of study patients, performed statistical analysis, and drafting the manuscript	participated in the design of the study, clinical assessment of study patients, performed statistical analysis, and drafting the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
2211500	18031583	SW	2	participated in clinical assessment of patients and drafting the manuscript	participated in clinical assessment of patients and drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
4005043	24780511	AB	2	wrote the first draft of the paper	wrote the first draft of the paper	Wrote the paper	Writing - Original Draft	YES
4005043	24780511	All authors	2	have contributed to subsequent drafts of the paper and have approved the final version	have contributed to subsequent drafts of the paper and have approved the final version	Wrote the paper	Writing - Original Draft	YES
4005043	24780511	MO	2	wrote the first draft of the paper	wrote the first draft of the paper	Wrote the paper	Writing - Original Draft	YES
5094078	27806695	AP	PLoS52	conceived and designed the project|wrote and edited the manuscript	conceived and designed the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5094078	27806695	AP	PLoS52	conceived and designed the project|wrote and edited the manuscript	wrote and edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5094078	27806695	CVDB	PLoS52	conceived and designed the project|assembled and annotated the transcriptomes|analysed the data|wrote and edited the manuscript	conceived and designed the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5094078	27806695	CVDB	PLoS52	conceived and designed the project|assembled and annotated the transcriptomes|analysed the data|wrote and edited the manuscript	assembled and annotated the transcriptomes	-	-	NO
5094078	27806695	CVDB	PLoS52	conceived and designed the project|assembled and annotated the transcriptomes|analysed the data|wrote and edited the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
5094078	27806695	CVDB	PLoS52	conceived and designed the project|assembled and annotated the transcriptomes|analysed the data|wrote and edited the manuscript	wrote and edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5094078	27806695	JS	PLoS52	conceived and designed the project|assembled and annotated the transcriptomes|wrote and edited the manuscript	conceived and designed the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5094078	27806695	JS	PLoS52	conceived and designed the project|assembled and annotated the transcriptomes|wrote and edited the manuscript	assembled and annotated the transcriptomes	-	-	NO
5094078	27806695	JS	PLoS52	conceived and designed the project|assembled and annotated the transcriptomes|wrote and edited the manuscript	wrote and edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5094078	27806695	PP	PLoS52	conceived and designed the project|wrote and edited the manuscript	conceived and designed the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5094078	27806695	PP	PLoS52	conceived and designed the project|wrote and edited the manuscript	wrote and edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5467005	28659938	D-YX	2	designed the experiments, discussed the results, edited the manuscript and supervised the project	designed the experiments, discussed the results, edited the manuscript and supervised the project	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Review & Editing	YES
5467005	28659938	LGa	2	designed the experiments, discussed the results, edited the manuscript and supervised the project	designed the experiments, discussed the results, edited the manuscript and supervised the project	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Review & Editing	YES
5467005	28659938	LGu	2	contributed to the plant genetic transformation	contributed to the plant genetic transformation	Performed the experiments	Investigation	YES
5467005	28659938	LZ	2	participated in the race cloning	participated in the race cloning	Performed the experiments	Investigation	YES
5467005	28659938	ML	2	designed the study, performed the experiments, interpreted the results, and wrote the manuscript	designed the study, performed the experiments, interpreted the results, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5467005	28659938	NG	2	contributed to the plant genetic transformation	contributed to the plant genetic transformation	Performed the experiments	Investigation	YES
5467005	28659938	TX	2	designed the experiments, discussed the results, edited the manuscript and supervised the project	designed the experiments, discussed the results, edited the manuscript and supervised the project	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Review & Editing	YES
5467005	28659938	WJ	2	participated in the dual-luciferase essays	participated in the dual-luciferase essays	-	-	NO
5467005	28659938	XJ	2	contributed to the hplc and uplc-ms analysis	contributed to the hplc and uplc-ms analysis	Performed the experiments	Investigation	YES
5467005	28659938	YP	2	participated in the dual-luciferase essays	participated in the dual-luciferase essays	-	-	NO
5467005	28659938	YW	2	participated in the cloning of the promoters	participated in the cloning of the promoters	Performed the experiments	Investigation	YES
5467005	28659938	YjL	2	contributed to the hplc and uplc-ms analysis	contributed to the hplc and uplc-ms analysis	Performed the experiments	Investigation	YES
5467005	28659938	YzL	2	participated in the cloning of the promoters	participated in the cloning of the promoters	Performed the experiments	Investigation	YES
4400145	25880632	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Carried out coding, verification and calculation using matlab	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400145	25880632	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Carried out coding, verification and calculation using matlab	Performed the experiments	Performed the experiments	Investigation	YES
4400145	25880632	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Carried out coding, verification and calculation using matlab	Analyzed the data	Analyzed the data	Formal analysis	YES
4400145	25880632	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Carried out coding, verification and calculation using matlab	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400145	25880632	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Carried out coding, verification and calculation using matlab	Carried out coding, verification and calculation using matlab	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Software|Validation	YES
4400145	25880632	ARMP	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400145	25880632	ARMP	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400145	25880632	ARMP	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400145	25880632	RUG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400145	25880632	RUG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400145	25880632	RUG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400145	25880632	ZRY	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4400145	25880632	ZRY	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4009484	24802716	AK	2	wrote the background section	wrote the background section	Wrote the paper	Writing - Original Draft	YES
4009484	24802716	All authors	2	have read and approved the final manuscript draft for journal submission|contributed to the study design and interpretation of the analysis results and commented on drafts of the manuscript	have read and approved the final manuscript draft for journal submission	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4009484	24802716	All authors	2	have read and approved the final manuscript draft for journal submission|contributed to the study design and interpretation of the analysis results and commented on drafts of the manuscript	contributed to the study design and interpretation of the analysis results and commented on drafts of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4009484	24802716	DW	2	revised the document for important intellectual content	revised the document for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4009484	24802716	HW	2	conceived the study and wrote the abstract and conclusions sections|wrote the background section	conceived the study and wrote the abstract and conclusions sections	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4009484	24802716	HW	2	conceived the study and wrote the abstract and conclusions sections|wrote the background section	wrote the background section	Wrote the paper	Writing - Original Draft	YES
4009484	24802716	PS	2	revised the document for important intellectual content	revised the document for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4009484	24802716	WM	2	conducted the statistical data analysis and interpretation of data and wrote the results section	conducted the statistical data analysis and interpretation of data and wrote the results section	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4400149	25880847	JB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400149	25880847	JB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400149	25880847	JB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400149	25880847	JB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400149	25880847	JLN	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400149	25880847	JLN	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400149	25880847	JLN	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400149	25880847	JLN	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400149	25880847	MW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400149	25880847	MW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400149	25880847	MW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400149	25880847	MW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5467580	28659948	KK	2	reviewed the literature and wrote the paper	reviewed the literature and wrote the paper	Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
2216023	18053126	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
2216023	18053126	CAL	2	provided additional inputs to further develop the scientific concept	provided additional inputs to further develop the scientific concept	Conceived and designed the experiments	Conceptualization	YES
2216023	18053126	EMS	2	conceived and proposed the hypothesis|drafted the manuscript|are the guarantors of the paper	conceived and proposed the hypothesis	Conceived and designed the experiments	Conceptualization	YES
2216023	18053126	EMS	2	conceived and proposed the hypothesis|drafted the manuscript|are the guarantors of the paper	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
2216023	18053126	EMS	2	conceived and proposed the hypothesis|drafted the manuscript|are the guarantors of the paper	are the guarantors of the paper	-	-	NO
2216023	18053126	KGM	2	provided additional inputs to further develop the scientific concept	provided additional inputs to further develop the scientific concept	Conceived and designed the experiments	Conceptualization	YES
2216023	18053126	NK	2	conceived and proposed the hypothesis|provided additional inputs to further develop the scientific concept|shared their clinical expertise and critically revised the manuscript|are the guarantors of the paper	conceived and proposed the hypothesis	Conceived and designed the experiments	Conceptualization	YES
2216023	18053126	NK	2	conceived and proposed the hypothesis|provided additional inputs to further develop the scientific concept|shared their clinical expertise and critically revised the manuscript|are the guarantors of the paper	provided additional inputs to further develop the scientific concept	Conceived and designed the experiments	Conceptualization	YES
2216023	18053126	NK	2	conceived and proposed the hypothesis|provided additional inputs to further develop the scientific concept|shared their clinical expertise and critically revised the manuscript|are the guarantors of the paper	shared their clinical expertise and critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
2216023	18053126	NK	2	conceived and proposed the hypothesis|provided additional inputs to further develop the scientific concept|shared their clinical expertise and critically revised the manuscript|are the guarantors of the paper	are the guarantors of the paper	-	-	NO
2216023	18053126	PB	2	provided additional inputs to further develop the scientific concept|drafted the manuscript	provided additional inputs to further develop the scientific concept	Conceived and designed the experiments	Conceptualization	YES
2216023	18053126	PB	2	provided additional inputs to further develop the scientific concept|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
2216023	18053126	RS	2	provided additional inputs to further develop the scientific concept	provided additional inputs to further develop the scientific concept	Conceived and designed the experiments	Conceptualization	YES
2216023	18053126	RV	2	conceived and proposed the hypothesis|provided additional inputs to further develop the scientific concept|drafted the manuscript|are the guarantors of the paper	conceived and proposed the hypothesis	Conceived and designed the experiments	Conceptualization	YES
2216023	18053126	RV	2	conceived and proposed the hypothesis|provided additional inputs to further develop the scientific concept|drafted the manuscript|are the guarantors of the paper	provided additional inputs to further develop the scientific concept	Conceived and designed the experiments	Conceptualization	YES
2216023	18053126	RV	2	conceived and proposed the hypothesis|provided additional inputs to further develop the scientific concept|drafted the manuscript|are the guarantors of the paper	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
2216023	18053126	RV	2	conceived and proposed the hypothesis|provided additional inputs to further develop the scientific concept|drafted the manuscript|are the guarantors of the paper	are the guarantors of the paper	-	-	NO
2216023	18053126	SS	2	provided additional inputs to further develop the scientific concept|shared their clinical expertise and critically revised the manuscript	provided additional inputs to further develop the scientific concept	Conceived and designed the experiments	Conceptualization	YES
2216023	18053126	SS	2	provided additional inputs to further develop the scientific concept|shared their clinical expertise and critically revised the manuscript	shared their clinical expertise and critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
3775444	23947567	G.S.	2	contributed equally to this work	contributed equally to this work	-	-	NO
3775444	23947567	I.G.M.	2	contributed equally to this work	contributed equally to this work	-	-	NO
3775444	23947567	S.B.	2	contributed equally to this work	contributed equally to this work	-	-	NO
5094085	27809762	AW	2	conducted fom experiments|processed and mapped the rna seq data|analysed the rna seq and deg data	conducted fom experiments	Performed the experiments	Investigation	YES
5094085	27809762	AW	2	conducted fom experiments|processed and mapped the rna seq data|analysed the rna seq and deg data	processed and mapped the rna seq data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5094085	27809762	AW	2	conducted fom experiments|processed and mapped the rna seq data|analysed the rna seq and deg data	analysed the rna seq and deg data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5094085	27809762	All authors	2	contributed to the draft and read and approved the final version	contributed to the draft and read and approved the final version	Wrote the paper	Writing - Original Draft	YES
5094085	27809762	GG	2	processed and mapped the rna seq data|performed deg analysis|analysed the rna seq and deg data	processed and mapped the rna seq data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5094085	27809762	GG	2	processed and mapped the rna seq data|performed deg analysis|analysed the rna seq and deg data	performed deg analysis	Performed the experiments	Investigation	YES
5094085	27809762	GG	2	processed and mapped the rna seq data|performed deg analysis|analysed the rna seq and deg data	analysed the rna seq and deg data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5094085	27809762	KS	2	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5094085	27809762	LT	2	conceived and designed the study|prepared rna and drafted the manuscript|conducted fom experiments|analysed the rna seq and deg data|conducted and analysed the qrt-pcr transcript data	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5094085	27809762	LT	2	conceived and designed the study|prepared rna and drafted the manuscript|conducted fom experiments|analysed the rna seq and deg data|conducted and analysed the qrt-pcr transcript data	prepared rna and drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5094085	27809762	LT	2	conceived and designed the study|prepared rna and drafted the manuscript|conducted fom experiments|analysed the rna seq and deg data|conducted and analysed the qrt-pcr transcript data	conducted fom experiments	Performed the experiments	Investigation	YES
5094085	27809762	LT	2	conceived and designed the study|prepared rna and drafted the manuscript|conducted fom experiments|analysed the rna seq and deg data|conducted and analysed the qrt-pcr transcript data	analysed the rna seq and deg data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5094085	27809762	LT	2	conceived and designed the study|prepared rna and drafted the manuscript|conducted fom experiments|analysed the rna seq and deg data|conducted and analysed the qrt-pcr transcript data	conducted and analysed the qrt-pcr transcript data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5094085	27809762	SB	2	conducted and analysed the qrt-pcr transcript data	conducted and analysed the qrt-pcr transcript data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4400151	25879442	AD	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400151	25879442	AD	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400151	25879442	AD	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400151	25879442	DT	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400151	25879442	GA	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400151	25879442	KS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400151	25879442	LM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400151	25879442	LNA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400151	25879442	LNA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400151	25879442	LNA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400151	25879442	LNA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400151	25879442	LNA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400151	25879442	NFT	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400151	25879442	NFT	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400151	25879442	NMB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
2222602	18047639	JSM	2	contributed to the design of the study and helped to draft the manuscript	contributed to the design of the study and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
2222602	18047639	KAF	2	contributed to the design of the study and helped to draft the manuscript	contributed to the design of the study and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
2222602	18047639	LCI	2	designed the study, collected the data and drafted the manuscript	designed the study, collected the data and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5467581	28659942	CC	2	interpreted the data	interpreted the data	Analyzed the data	Formal analysis	YES
5467581	28659942	CM	2	performed experiments|interpreted the data	performed experiments	Performed the experiments	Investigation	YES
5467581	28659942	CM	2	performed experiments|interpreted the data	interpreted the data	Analyzed the data	Formal analysis	YES
5467581	28659942	CR	2	designed the research|interpreted the data|wrote the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
5467581	28659942	CR	2	designed the research|interpreted the data|wrote the manuscript	interpreted the data	Analyzed the data	Formal analysis	YES
5467581	28659942	CR	2	designed the research|interpreted the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5467581	28659942	DJ	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5467581	28659942	FG	2	interpreted the data	interpreted the data	Analyzed the data	Formal analysis	YES
5467581	28659942	JJ	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5467581	28659942	LF	2	designed the research|performed experiments|interpreted the data|wrote the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
5467581	28659942	LF	2	designed the research|performed experiments|interpreted the data|wrote the manuscript	performed experiments	Performed the experiments	Investigation	YES
5467581	28659942	LF	2	designed the research|performed experiments|interpreted the data|wrote the manuscript	interpreted the data	Analyzed the data	Formal analysis	YES
5467581	28659942	LF	2	designed the research|performed experiments|interpreted the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5467581	28659942	ML-C	2	interpreted the data	interpreted the data	Analyzed the data	Formal analysis	YES
5094087	27809776	GZW	2	collected the samples	collected the samples	Performed the experiments	Investigation	YES
5094087	27809776	JMW	2	managed the project|designed the analyses	managed the project	-	Project administration	YES
5094087	27809776	JMW	2	managed the project|designed the analyses	designed the analyses	Conceived and designed the experiments|Analyzed the data	Formal analysis	YES
5094087	27809776	LH	2	designed the analyses|collected the samples	designed the analyses	Conceived and designed the experiments|Analyzed the data	Formal analysis	YES
5094087	27809776	LH	2	designed the analyses|collected the samples	collected the samples	Performed the experiments	Investigation	YES
5094087	27809776	TLC	2	carried out the bioinformatics analyses and other works of this study	carried out the bioinformatics analyses and other works of this study	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5094087	27809776	ZBJ	2	designed the analyses|collected the samples	designed the analyses	Conceived and designed the experiments|Analyzed the data	Formal analysis	YES
5094087	27809776	ZBJ	2	designed the analyses|collected the samples	collected the samples	Performed the experiments	Investigation	YES
5094087	27809776	ZHL	2	designed the analyses|carried out the bioinformatics analyses and other works of this study|collected the samples|wrote the manuscript	designed the analyses	Conceived and designed the experiments|Analyzed the data	Formal analysis	YES
5094087	27809776	ZHL	2	designed the analyses|carried out the bioinformatics analyses and other works of this study|collected the samples|wrote the manuscript	carried out the bioinformatics analyses and other works of this study	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5094087	27809776	ZHL	2	designed the analyses|carried out the bioinformatics analyses and other works of this study|collected the samples|wrote the manuscript	collected the samples	Performed the experiments	Investigation	YES
5094087	27809776	ZHL	2	designed the analyses|carried out the bioinformatics analyses and other works of this study|collected the samples|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4400152	25881241	AK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4400152	25881241	IP	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400152	25881241	RFW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400152	25881241	RFW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400152	25881241	RFW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400152	25881241	RFW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400152	25881241	RKM	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4400152	25881241	TJ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400152	25881241	TJ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400152	25881241	TJ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400152	25881241	YMK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400152	25881241	YMK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400152	25881241	YMK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4434173	26097844	Liehua Liu	2	contributed equally to this study	contributed equally to this study	-	-	NO
4434173	26097844	Yibo Gan	2	contributed equally to this study	contributed equally to this study	-	-	NO
3952113	24392701	S.W.	2	contributed equally to this work	contributed equally to this work	-	-	NO
3952113	24392701	V.P.	2	contributed equally to this work	contributed equally to this work	-	-	NO
2248203	18215326	RA	2	was responsible for the conception and overall implementation of the project	was responsible for the conception and overall implementation of the project	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5468386	28659936	All authors	2	contributed critically to the drafts and gave final approval for publication	contributed critically to the drafts and gave final approval for publication	Wrote the paper	Writing - Original Draft	YES
5468386	28659936	JB	2	collected and analyzed the data	collected and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5468386	28659936	JH	2	collected and analyzed the data	collected and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5468386	28659936	JS	2	collected and analyzed the data	collected and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5468386	28659936	PM	2	conceived the ideas and designed methodology	conceived the ideas and designed methodology	Conceived and designed the experiments|Performed the experiments	Conceptualization|Methodology	YES
5468386	28659936	PR	2	conceived the ideas and designed methodology	conceived the ideas and designed methodology	Conceived and designed the experiments|Performed the experiments	Conceptualization|Methodology	YES
5468386	28659936	ST	2	conceived the ideas and designed methodology|collected and analyzed the data|led the writing of the manuscript	conceived the ideas and designed methodology	Conceived and designed the experiments|Performed the experiments	Conceptualization|Methodology	YES
5468386	28659936	ST	2	conceived the ideas and designed methodology|collected and analyzed the data|led the writing of the manuscript	collected and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5468386	28659936	ST	2	conceived the ideas and designed methodology|collected and analyzed the data|led the writing of the manuscript	led the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
4016737	24815415	All authors	2	participated in the planning and conception of the manuscript	participated in the planning and conception of the manuscript	Conceived and designed the experiments	Conceptualization|Methodology	YES
4016737	24815415	IB	2	drafted the article, and all authors participated in interpreting the data and critically revised the manuscript	drafted the article, and all authors participated in interpreting the data and critically revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
4400155	25881157	AN	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4400155	25881157	AN	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400155	25881157	BV	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4400155	25881157	BV	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4400155	25881157	IM	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4400155	25881157	IM	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4400155	25881157	JJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400155	25881157	JJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400155	25881157	JJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400155	25881157	JJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400155	25881157	RB	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4400155	25881157	RM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400155	25881157	RM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400155	25881157	RM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400155	25881157	RT	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4400155	25881157	RV	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4400155	25881157	RV	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5094094	27809759	CS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5094094	27809759	CS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
5094094	27809759	CS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5094094	27809759	CS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5094094	27809759	FC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5094094	27809759	FRZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5094094	27809759	LJL	PLoS5	Collected the soil sample	Collected the soil sample	Performed the experiments	Investigation	YES
5094094	27809759	TJC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5094094	27809759	XQZ	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5094094	27809759	XRW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5094094	27809759	YBL	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5094094	27809759	YDZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5094094	27809759	YS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5094094	27809759	YS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5094094	27809759	ZJX	PLoS5	Collected the soil sample|Performed the experiments|Analyzed the data	Collected the soil sample	Performed the experiments	Investigation	YES
5094094	27809759	ZJX	PLoS5	Collected the soil sample|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
5094094	27809759	ZJX	PLoS5	Collected the soil sample|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5094094	27809759	ZL	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4017591	24815595	ED	2	supervised data collection, contributed to analysis and reviewed drafts of the paper	supervised data collection, contributed to analysis and reviewed drafts of the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
4017591	24815595	HM	2	facilitated research in a hospital setting, arranged recruitment of participants and reviewed drafts of the paper	facilitated research in a hospital setting, arranged recruitment of participants and reviewed drafts of the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
4017591	24815595	JB	2	designed the formative study, developed the protocol, and led data analysis and write-up	designed the formative study, developed the protocol, and led data analysis and write-up	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology	YES
4017591	24815595	RF	2	contributed to study design, data analysis, drafting the paper and leads the community-based trial for which this study comprised formative research	contributed to study design, data analysis, drafting the paper and leads the community-based trial for which this study comprised formative research	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Original Draft	YES
4017591	24815595	TB	2	was responsible for data management and reviewed drafts of the paper	was responsible for data management and reviewed drafts of the paper	Analyzed the data|Wrote the paper	Data curation|Writing - Original Draft|Writing - Review & Editing	YES
4434176	26064888	Geng Yin	2	contributed equally to this work	contributed equally to this work	-	-	NO
4434176	26064888	Yan Li	2	contributed equally to this work	contributed equally to this work	-	-	NO
5468418	28659944	DL	2	designed the experiments|performed the experiments and wrote the manuscript|analyzed the data and edited the article	designed the experiments	Conceived and designed the experiments	Methodology	YES
5468418	28659944	DL	2	designed the experiments|performed the experiments and wrote the manuscript|analyzed the data and edited the article	performed the experiments and wrote the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5468418	28659944	DL	2	designed the experiments|performed the experiments and wrote the manuscript|analyzed the data and edited the article	analyzed the data and edited the article	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5468418	28659944	DY	2	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5468418	28659944	GL	2	analyzed the data and edited the article	analyzed the data and edited the article	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5468418	28659944	HW	2	analyzed the data and edited the article	analyzed the data and edited the article	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4400157	25881166	BS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400157	25881166	BS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400157	25881166	BS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400157	25881166	BS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400157	25881166	BVLN	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4400157	25881166	BWF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400157	25881166	BWF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400157	25881166	BWF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400157	25881166	CHMK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400157	25881166	CHMK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400157	25881166	CHMK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400157	25881166	EJR	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4400157	25881166	FAS	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4400157	25881166	GAB	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4400157	25881166	KAK	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4400157	25881166	KAK	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4400157	25881166	RRG	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4400157	25881166	RRG	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4021989	24836607	All authors	2	reviewed the article for important intellectual content and final approval	reviewed the article for important intellectual content and final approval	Wrote the paper	Writing - Review & Editing	YES
5094136	27806702	JP	2	planned the in silico analyses|designed and performed the in silico analyses|wrote the manuscript	planned the in silico analyses	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
5094136	27806702	JP	2	planned the in silico analyses|designed and performed the in silico analyses|wrote the manuscript	designed and performed the in silico analyses	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5094136	27806702	JP	2	planned the in silico analyses|designed and performed the in silico analyses|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5094136	27806702	PL	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5094136	27806702	PR	2	designed and performed the experiments|planned the in silico analyses|wrote the manuscript	designed and performed the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5094136	27806702	PR	2	designed and performed the experiments|planned the in silico analyses|wrote the manuscript	planned the in silico analyses	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
5094136	27806702	PR	2	designed and performed the experiments|planned the in silico analyses|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5468422	28659947	SK	2	has assisted in consulting literature and preparing the manuscript	has assisted in consulting literature and preparing the manuscript	Wrote the paper	Writing - Original Draft	YES
5468422	28659947	SM	2	has conceptualized the idea, consulted the literature and prepared the manuscript	has conceptualized the idea, consulted the literature and prepared the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
2292208	18307778	All authors	2	reviewed drafts critically and contributed to ideas and writing on multiple occasions	reviewed drafts critically and contributed to ideas and writing on multiple occasions	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
2292208	18307778	SJ	2	wrote the first draft of the paper	wrote the first draft of the paper	Wrote the paper	Writing - Original Draft	YES
3997221	24490651	All authors	2	have given approval to the final version of the manuscript	have given approval to the final version of the manuscript	-	-	NO
4400158	25880452	BY	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400158	25880452	JN	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400158	25880452	KW	PLoS5	Reviewed the manuscript	Reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
4400158	25880452	PZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4400158	25880452	QH	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400158	25880452	RD	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400158	25880452	TW	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400158	25880452	TW	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400158	25880452	TW	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400158	25880452	ZJ	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5094146	27809765	All authors	2	provided input during the writing of the manuscript	provided input during the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5094146	27809765	KMS	2	designed the research|isolated dna and rna|performed the expression analysis|performed the methylation analysis|wrote the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
5094146	27809765	KMS	2	designed the research|isolated dna and rna|performed the expression analysis|performed the methylation analysis|wrote the manuscript	isolated dna and rna	Performed the experiments	Investigation	YES
5094146	27809765	KMS	2	designed the research|isolated dna and rna|performed the expression analysis|performed the methylation analysis|wrote the manuscript	performed the expression analysis	Performed the experiments	Investigation	YES
5094146	27809765	KMS	2	designed the research|isolated dna and rna|performed the expression analysis|performed the methylation analysis|wrote the manuscript	performed the methylation analysis	Performed the experiments	Investigation	YES
5094146	27809765	KMS	2	designed the research|isolated dna and rna|performed the expression analysis|performed the methylation analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5094146	27809765	LAR	2	designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
5094146	27809765	LBS	2	designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
5094146	27809765	MAMG	2	designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
5094146	27809765	OM	2	designed the research|performed the expression analysis|performed the methylation analysis	designed the research	Conceived and designed the experiments	Methodology	YES
5094146	27809765	OM	2	designed the research|performed the expression analysis|performed the methylation analysis	performed the expression analysis	Performed the experiments	Investigation	YES
5094146	27809765	OM	2	designed the research|performed the expression analysis|performed the methylation analysis	performed the methylation analysis	Performed the experiments	Investigation	YES
5094146	27809765	RWJ	2	designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
5094146	27809765	YL	2	performed the expression analysis|wrote the manuscript	performed the expression analysis	Performed the experiments	Investigation	YES
5094146	27809765	YL	2	performed the expression analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4024656	24836775	AJ	2	performed data management, statistical analysis, drafting and submission of final manuscript	performed data management, statistical analysis, drafting and submission of final manuscript	Analyzed the data|Wrote the paper	Data curation|Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
4024656	24836775	AK	2	have read and approved the final manuscript	have read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4024656	24836775	CL	2	have read and approved the final manuscript	have read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4024656	24836775	ML	2	initiated concept ideas and reviewed the statistical analysis and final manuscript	initiated concept ideas and reviewed the statistical analysis and final manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Review & Editing	YES
4024656	24836775	MM	2	have read and approved the final manuscript	have read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4024656	24836775	NK	2	have read and approved the final manuscript	have read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4024656	24836775	PC	2	have read and approved the final manuscript	have read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4024656	24836775	PL	2	have read and approved the final manuscript	have read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4024656	24836775	PP	2	have read and approved the final manuscript	have read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4024656	24836775	RD	2	have read and approved the final manuscript	have read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4024656	24836775	SS	2	have read and approved the final manuscript	have read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4024656	24836775	TM	2	have read and approved the final manuscript	have read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4024656	24836775	TS	2	have read and approved the final manuscript|have read and approved the final manuscript	have read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4024656	24836775	TS	2	have read and approved the final manuscript|have read and approved the final manuscript	have read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5468429	28659954	AA	2	carried out the field trials	carried out the field trials	Performed the experiments	Investigation	YES
5468429	28659954	BY	2	designed the study|carried out the field trials|interpreted the segregation pattern of the progenies	designed the study	Conceived and designed the experiments	Methodology	YES
5468429	28659954	BY	2	designed the study|carried out the field trials|interpreted the segregation pattern of the progenies	carried out the field trials	Performed the experiments	Investigation	YES
5468429	28659954	BY	2	designed the study|carried out the field trials|interpreted the segregation pattern of the progenies	interpreted the segregation pattern of the progenies	Analyzed the data	Formal analysis	YES
5468429	28659954	DF	2	interpreted the chemistry data	interpreted the chemistry data	Analyzed the data	Formal analysis	YES
5468429	28659954	GS	2	interpreted the segregation pattern of the progenies	interpreted the segregation pattern of the progenies	Analyzed the data	Formal analysis	YES
5468429	28659954	GY	2	designed the study|interpreted the segregation pattern of the progenies	designed the study	Conceived and designed the experiments	Methodology	YES
5468429	28659954	GY	2	designed the study|interpreted the segregation pattern of the progenies	interpreted the segregation pattern of the progenies	Analyzed the data	Formal analysis	YES
5468429	28659954	MA	2	designed the study|carried out the field trials|interpreted the chemistry data	designed the study	Conceived and designed the experiments	Methodology	YES
5468429	28659954	MA	2	designed the study|carried out the field trials|interpreted the chemistry data	carried out the field trials	Performed the experiments	Investigation	YES
5468429	28659954	MA	2	designed the study|carried out the field trials|interpreted the chemistry data	interpreted the chemistry data	Analyzed the data	Formal analysis	YES
5468429	28659954	PS	2	designed the study|interpreted the chemistry data	designed the study	Conceived and designed the experiments	Methodology	YES
5468429	28659954	PS	2	designed the study|interpreted the chemistry data	interpreted the chemistry data	Analyzed the data	Formal analysis	YES
5468429	28659954	RM	2	started the research which led to this and other studies|interpreted the segregation pattern of the progenies	started the research which led to this and other studies	-	-	NO
5468429	28659954	RM	2	started the research which led to this and other studies|interpreted the segregation pattern of the progenies	interpreted the segregation pattern of the progenies	Analyzed the data	Formal analysis	YES
2358919	18419808	AH	2	participated in the study design, the data analysis, and coordination	participated in the study design, the data analysis, and coordination	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology|Project administration	YES
2358919	18419808	PO	2	participated in the design of the study and carried out interviews	participated in the design of the study and carried out interviews	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
2358919	18419808	PW	2	conceived of the study and participated in its design and coordination	conceived of the study and participated in its design and coordination	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
2358919	18419808	TAN	2	participated in the design of the study, conduct the data collection and the dada analysis	participated in the design of the study, conduct the data collection and the dada analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
2358919	18419808	YPN	2	carried out the data collection and the data analysis	carried out the data collection and the data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3997223	24422464	All authors	2	have given approval to the final version of the manuscript	have given approval to the final version of the manuscript	-	-	NO
4400159	25879660	BZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400159	25879660	BZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400159	25879660	BZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400159	25879660	JC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4400159	25879660	JC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400159	25879660	QL	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400159	25879660	QL	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400159	25879660	TZ	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400159	25879660	YC	PLoS5	Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4400159	25879660	YC	PLoS5	Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4400159	25879660	YC	PLoS5	Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4400159	25879660	YC	PLoS5	Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4400159	25879660	YC	PLoS5	Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400159	25879660	YC	PLoS5	Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400159	25879660	YW	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4400159	25879660	YW	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4400159	25879660	YW	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5089648	27241582	A. Mitani	1	Final approval of the version to be submitted	Final approval of the version to be submitted	-	-	NO
5089648	27241582	H. Matsumoto	1	Drafting of the article or critical revision for important intellectual content|Final approval of the version to be submitted	Drafting of the article or critical revision for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5089648	27241582	H. Matsumoto	1	Drafting of the article or critical revision for important intellectual content|Final approval of the version to be submitted	Final approval of the version to be submitted	-	-	NO
5089648	27241582	M. Hori	1	Final approval of the version to be submitted	Final approval of the version to be submitted	-	-	NO
5089648	27241582	M. Sugimoto	1	Conception and design of the study|Drafting of the article or critical revision for important intellectual content|Final approval of the version to be submitted	Conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5089648	27241582	M. Sugimoto	1	Conception and design of the study|Drafting of the article or critical revision for important intellectual content|Final approval of the version to be submitted	Drafting of the article or critical revision for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5089648	27241582	M. Sugimoto	1	Conception and design of the study|Drafting of the article or critical revision for important intellectual content|Final approval of the version to be submitted	Final approval of the version to be submitted	-	-	NO
5089648	27241582	N. Otsuka	1	Conception and design of the study|Drafting of the article or critical revision for important intellectual content|Final approval of the version to be submitted	Conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5089648	27241582	N. Otsuka	1	Conception and design of the study|Drafting of the article or critical revision for important intellectual content|Final approval of the version to be submitted	Drafting of the article or critical revision for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5089648	27241582	N. Otsuka	1	Conception and design of the study|Drafting of the article or critical revision for important intellectual content|Final approval of the version to be submitted	Final approval of the version to be submitted	-	-	NO
5089648	27241582	S. Kaku	1	Conception and design of the study|Drafting of the article or critical revision for important intellectual content|Final approval of the version to be submitted	Conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5089648	27241582	S. Kaku	1	Conception and design of the study|Drafting of the article or critical revision for important intellectual content|Final approval of the version to be submitted	Drafting of the article or critical revision for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5089648	27241582	S. Kaku	1	Conception and design of the study|Drafting of the article or critical revision for important intellectual content|Final approval of the version to be submitted	Final approval of the version to be submitted	-	-	NO
5089648	27241582	S. Sekine	1	Final approval of the version to be submitted	Final approval of the version to be submitted	-	-	NO
5089648	27241582	T. Ichihara	1	Final approval of the version to be submitted	Final approval of the version to be submitted	-	-	NO
5089648	27241582	Y. Toda	1	Conception and design of the study|Drafting of the article or critical revision for important intellectual content|Final approval of the version to be submitted	Conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5089648	27241582	Y. Toda	1	Conception and design of the study|Drafting of the article or critical revision for important intellectual content|Final approval of the version to be submitted	Drafting of the article or critical revision for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5089648	27241582	Y. Toda	1	Conception and design of the study|Drafting of the article or critical revision for important intellectual content|Final approval of the version to be submitted	Final approval of the version to be submitted	-	-	NO
509418	15310388	DP	2	conceived of the project and participated in its design and coordination	conceived of the project and participated in its design and coordination	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
509418	15310388	PCR	2	gel electrophoresis	gel electrophoresis	Performed the experiments	Investigation	YES
509418	15310388	SV	2	conceived of the project and participated in its design and coordination	conceived of the project and participated in its design and coordination	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
5468436	28659956	C-GH	2	conceived the research plan and supervised the experiments	conceived the research plan and supervised the experiments	Conceived and designed the experiments	Conceptualization|Supervision	YES
5468436	28659956	C-XH	2	conceived the research plan and supervised the experiments	conceived the research plan and supervised the experiments	Conceived and designed the experiments	Conceptualization|Supervision	YES
5468436	28659956	H-BH	2	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5468436	28659956	J-JZ	2	conceived the research plan and supervised the experiments|drafted the manuscript	conceived the research plan and supervised the experiments	Conceived and designed the experiments	Conceptualization|Supervision	YES
5468436	28659956	J-JZ	2	conceived the research plan and supervised the experiments|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5468436	28659956	J-QY	2	conceived the research plan and supervised the experiments	conceived the research plan and supervised the experiments	Conceived and designed the experiments	Conceptualization|Supervision	YES
5468436	28659956	J-XL	2	conceived the research plan and supervised the experiments|drafted the manuscript	conceived the research plan and supervised the experiments	Conceived and designed the experiments	Conceptualization|Supervision	YES
5468436	28659956	J-XL	2	conceived the research plan and supervised the experiments|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5468436	28659956	J-YG	2	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5468436	28659956	J-ZZ	2	conceived the research plan and supervised the experiments	conceived the research plan and supervised the experiments	Conceived and designed the experiments	Conceptualization|Supervision	YES
5468436	28659956	JZ	2	conceived the research plan and supervised the experiments|performed the experiments and analyzed the data	conceived the research plan and supervised the experiments	Conceived and designed the experiments	Conceptualization|Supervision	YES
5468436	28659956	JZ	2	conceived the research plan and supervised the experiments|performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5468436	28659956	JZ-Z	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5468436	28659956	X-JH	2	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5468436	28659956	Y-XD	2	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4434189	26064964	Xiaomin Cen	2	contributed equally to this work	contributed equally to this work	-	-	NO
4434189	26064964	Yuan Liu	2	contributed equally to this work	contributed equally to this work	-	-	NO
4400161	25880905	BCCL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Supervision of study	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400161	25880905	BCCL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Supervision of study	Performed the experiments	Performed the experiments	Investigation	YES
4400161	25880905	BCCL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Supervision of study	Analyzed the data	Analyzed the data	Formal analysis	YES
4400161	25880905	BCCL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Supervision of study	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400161	25880905	BCCL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Supervision of study	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400161	25880905	BCCL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Supervision of study	Supervision of study	-	Supervision	YES
4400161	25880905	CC	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400161	25880905	CC	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400161	25880905	GCHK	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400161	25880905	GCHK	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400161	25880905	MTKW	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Supervision of study	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400161	25880905	MTKW	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Supervision of study	Performed the experiments	Performed the experiments	Investigation	YES
4400161	25880905	MTKW	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Supervision of study	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400161	25880905	MTKW	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Supervision of study	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400161	25880905	MTKW	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Supervision of study	Supervision of study	-	Supervision	YES
4400161	25880905	SJF	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper|Supervision of study	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400161	25880905	SJF	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper|Supervision of study	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400161	25880905	SJF	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper|Supervision of study	Supervision of study	-	Supervision	YES
4032505	24855985	CJH	1	Study design and implementation|Data analysis|Drafting manuscript and final approval	Study design and implementation	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4032505	24855985	CJH	1	Study design and implementation|Data analysis|Drafting manuscript and final approval	Data analysis	Analyzed the data	Formal analysis	YES
4032505	24855985	CJH	1	Study design and implementation|Data analysis|Drafting manuscript and final approval	Drafting manuscript and final approval	Wrote the paper	Writing - Original Draft	YES
4032505	24855985	FM	1	Study design and implementation|Drafting manuscript and final approval	Study design and implementation	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4032505	24855985	FM	1	Study design and implementation|Drafting manuscript and final approval	Drafting manuscript and final approval	Wrote the paper	Writing - Original Draft	YES
4032505	24855985	JDH	1	Study design and implementation|Drafting manuscript and final approval	Study design and implementation	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4032505	24855985	JDH	1	Study design and implementation|Drafting manuscript and final approval	Drafting manuscript and final approval	Wrote the paper	Writing - Original Draft	YES
4032505	24855985	NAM	1	Study design and implementation|Drafting manuscript and final approval	Study design and implementation	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4032505	24855985	NAM	1	Study design and implementation|Drafting manuscript and final approval	Drafting manuscript and final approval	Wrote the paper	Writing - Original Draft	YES
4032505	24855985	REC	1	Study design and implementation|Drafting manuscript and final approval	Study design and implementation	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4032505	24855985	REC	1	Study design and implementation|Drafting manuscript and final approval	Drafting manuscript and final approval	Wrote the paper	Writing - Original Draft	YES
4032505	24855985	SC	1	Data analysis|Drafting manuscript and final approval	Data analysis	Analyzed the data	Formal analysis	YES
4032505	24855985	SC	1	Data analysis|Drafting manuscript and final approval	Drafting manuscript and final approval	Wrote the paper	Writing - Original Draft	YES
4032505	24855985	SL	1	Study design and implementation|Drafting manuscript and final approval	Study design and implementation	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4032505	24855985	SL	1	Study design and implementation|Drafting manuscript and final approval	Drafting manuscript and final approval	Wrote the paper	Writing - Original Draft	YES
2365956	18439274	DMG	7	design, editorial support and contribution of important intellectual content, research fund collection	design, editorial support and contribution of important intellectual content, research fund collection	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
2365956	18439274	JSO	7	conception and design, data collection and analysis in cardiac and skeletal muscle tissues, figure and manuscript preparation	conception and design, data collection and analysis in cardiac and skeletal muscle tissues, figure and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Visualization|Writing - Original Draft	YES
2365956	18439274	LAB	7	hplc analyses of glutathione metabolites in cardiac and skeletal muscle tissues	hplc analyses of glutathione metabolites in cardiac and skeletal muscle tissues	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
2365956	18439274	YIA	7	real time pcr analyses, contribution of important intellectual content	real time pcr analyses, contribution of important intellectual content	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5095962	27809764	CSN	PLoS5	Conceived and designed experiments|Performed the experiments|Analyzed the data|Wrote the manuscript	Conceived and designed experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5095962	27809764	CSN	PLoS5	Conceived and designed experiments|Performed the experiments|Analyzed the data|Wrote the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
5095962	27809764	CSN	PLoS5	Conceived and designed experiments|Performed the experiments|Analyzed the data|Wrote the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
5095962	27809764	CSN	PLoS5	Conceived and designed experiments|Performed the experiments|Analyzed the data|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5095962	27809764	ERP	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5095962	27809764	JN	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5095962	27809764	JNB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5095962	27809764	KAW	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
5095962	27809764	KAW	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5095962	27809764	PK	PLoS5	Conceived and designed experiments|Wrote the manuscript	Conceived and designed experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5095962	27809764	PK	PLoS5	Conceived and designed experiments|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5095962	27809764	RBB	PLoS5	Conceived and designed experiments|Wrote the manuscript	Conceived and designed experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5095962	27809764	RBB	PLoS5	Conceived and designed experiments|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5468454	28659959	CB	2	conducted the experiment	conducted the experiment	Performed the experiments	Investigation	YES
5468454	28659959	ER	2	conducted the experiment	conducted the experiment	Performed the experiments	Investigation	YES
5468454	28659959	FL	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5468454	28659959	GA	2	conducted the experiment	conducted the experiment	Performed the experiments	Investigation	YES
5468454	28659959	GM	2	conducted the experiment	conducted the experiment	Performed the experiments	Investigation	YES
5468454	28659959	MC	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5468454	28659959	MH	2	conducted the experiment|wrote the manuscript	conducted the experiment	Performed the experiments	Investigation	YES
5468454	28659959	MH	2	conducted the experiment|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5468454	28659959	MM	2	conducted the experiment	conducted the experiment	Performed the experiments	Investigation	YES
5468454	28659959	SC	2	conducted the experiment	conducted the experiment	Performed the experiments	Investigation	YES
5468454	28659959	SLC	2	conducted the experiment	conducted the experiment	Performed the experiments	Investigation	YES
4400162	25881307	CG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400162	25881307	CG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400162	25881307	CG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400162	25881307	CG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400162	25881307	JMP	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400162	25881307	JMP	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400162	25881307	JMP	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400162	25881307	MC	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400162	25881307	MC	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400162	25881307	MS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400162	25881307	MS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400162	25881307	MS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2365957	18373851	CTL	2	conceived the study design, which was reviewed, revised, and approved by all of the authors|wrote, reviewed, and edited the protocol|was responsible for logistical issues and study conduct, such as ensuring accurate completion of data collection forms	conceived the study design, which was reviewed, revised, and approved by all of the authors	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
2365957	18373851	CTL	2	conceived the study design, which was reviewed, revised, and approved by all of the authors|wrote, reviewed, and edited the protocol|was responsible for logistical issues and study conduct, such as ensuring accurate completion of data collection forms	wrote, reviewed, and edited the protocol	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft|Writing - Review & Editing	YES
2365957	18373851	CTL	2	conceived the study design, which was reviewed, revised, and approved by all of the authors|wrote, reviewed, and edited the protocol|was responsible for logistical issues and study conduct, such as ensuring accurate completion of data collection forms	was responsible for logistical issues and study conduct, such as ensuring accurate completion of data collection forms	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
2365957	18373851	ED	2	enrolled study subjects	enrolled study subjects	Performed the experiments	Investigation	YES
2365957	18373851	GEP	2	wrote, reviewed, and edited the protocol|drafted the manuscript, which was reviewed and edited by all authors	wrote, reviewed, and edited the protocol	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft|Writing - Review & Editing	YES
2365957	18373851	GEP	2	wrote, reviewed, and edited the protocol|drafted the manuscript, which was reviewed and edited by all authors	drafted the manuscript, which was reviewed and edited by all authors	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
2365957	18373851	KAP	2	conceived the study design, which was reviewed, revised, and approved by all of the authors|wrote, reviewed, and edited the protocol	conceived the study design, which was reviewed, revised, and approved by all of the authors	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
2365957	18373851	KAP	2	conceived the study design, which was reviewed, revised, and approved by all of the authors|wrote, reviewed, and edited the protocol	wrote, reviewed, and edited the protocol	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft|Writing - Review & Editing	YES
2365957	18373851	KYS	2	was responsible for overall conduct and monitoring of safety parameters for the study|conceived the study design, which was reviewed, revised, and approved by all of the authors|wrote, reviewed, and edited the protocol|enrolled study subjects	was responsible for overall conduct and monitoring of safety parameters for the study	Performed the experiments	Investigation|Supervision	YES
2365957	18373851	KYS	2	was responsible for overall conduct and monitoring of safety parameters for the study|conceived the study design, which was reviewed, revised, and approved by all of the authors|wrote, reviewed, and edited the protocol|enrolled study subjects	conceived the study design, which was reviewed, revised, and approved by all of the authors	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
2365957	18373851	KYS	2	was responsible for overall conduct and monitoring of safety parameters for the study|conceived the study design, which was reviewed, revised, and approved by all of the authors|wrote, reviewed, and edited the protocol|enrolled study subjects	wrote, reviewed, and edited the protocol	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft|Writing - Review & Editing	YES
2365957	18373851	KYS	2	was responsible for overall conduct and monitoring of safety parameters for the study|conceived the study design, which was reviewed, revised, and approved by all of the authors|wrote, reviewed, and edited the protocol|enrolled study subjects	enrolled study subjects	Performed the experiments	Investigation	YES
2365957	18373851	MAF	2	enrolled study subjects	enrolled study subjects	Performed the experiments	Investigation	YES
2365957	18373851	QL	2	wrote, reviewed, and edited the protocol|performed the statistical analysis	wrote, reviewed, and edited the protocol	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft|Writing - Review & Editing	YES
2365957	18373851	QL	2	wrote, reviewed, and edited the protocol|performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
2365957	18373851	WGW	2	enrolled study subjects	enrolled study subjects	Performed the experiments	Investigation	YES
5468936	28659960	JR	2	wrote the first draft of the manuscript|revised and improved the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
5468936	28659960	JR	2	wrote the first draft of the manuscript|revised and improved the manuscript	revised and improved the manuscript	Wrote the paper	Writing - Review & Editing	YES
5468936	28659960	MB	2	revised and improved the manuscript	revised and improved the manuscript	Wrote the paper	Writing - Review & Editing	YES
5468936	28659960	The authors	2	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	Performed the experiments	Investigation	YES
5096308	27809760	AJN	1	Performed wet lab experiments|Data analysis|Interpretation of results|Wrote the manuscript	Performed wet lab experiments	Performed the experiments	Investigation	YES
5096308	27809760	AJN	1	Performed wet lab experiments|Data analysis|Interpretation of results|Wrote the manuscript	Data analysis	Analyzed the data	Formal analysis	YES
5096308	27809760	AJN	1	Performed wet lab experiments|Data analysis|Interpretation of results|Wrote the manuscript	Interpretation of results	Analyzed the data	Formal analysis	YES
5096308	27809760	AJN	1	Performed wet lab experiments|Data analysis|Interpretation of results|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5096308	27809760	BJL	1	Performed wet lab experiments	Performed wet lab experiments	Performed the experiments	Investigation	YES
5096308	27809760	CMD	1	Performed wet lab experiments	Performed wet lab experiments	Performed the experiments	Investigation	YES
5096308	27809760	DJS	1	Conceived the study|Design of rna seq|Data analysis|Interpretation of results|Wrote the manuscript	Conceived the study	Conceived and designed the experiments	Conceptualization	YES
5096308	27809760	DJS	1	Conceived the study|Design of rna seq|Data analysis|Interpretation of results|Wrote the manuscript	Design of rna seq	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5096308	27809760	DJS	1	Conceived the study|Design of rna seq|Data analysis|Interpretation of results|Wrote the manuscript	Data analysis	Analyzed the data	Formal analysis	YES
5096308	27809760	DJS	1	Conceived the study|Design of rna seq|Data analysis|Interpretation of results|Wrote the manuscript	Interpretation of results	Analyzed the data	Formal analysis	YES
5096308	27809760	DJS	1	Conceived the study|Design of rna seq|Data analysis|Interpretation of results|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5096308	27809760	EM	1	Conceived the study|Interpretation of results|Wrote the manuscript	Conceived the study	Conceived and designed the experiments	Conceptualization	YES
5096308	27809760	EM	1	Conceived the study|Interpretation of results|Wrote the manuscript	Interpretation of results	Analyzed the data	Formal analysis	YES
5096308	27809760	EM	1	Conceived the study|Interpretation of results|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5096308	27809760	KML	1	Performed wet lab experiments	Performed wet lab experiments	Performed the experiments	Investigation	YES
5096308	27809760	VBG	1	Performed wet lab experiments	Performed wet lab experiments	Performed the experiments	Investigation	YES
4048591	24894377	C Ndondoki	2	performed the analysis|was in charge of coordinating the paediatric procedures and of drafting the manuscript, which all authors subsequently reviewed, edited and approved	performed the analysis	Performed the experiments	Investigation	YES
4048591	24894377	C Ndondoki	2	performed the analysis|was in charge of coordinating the paediatric procedures and of drafting the manuscript, which all authors subsequently reviewed, edited and approved	was in charge of coordinating the paediatric procedures and of drafting the manuscript, which all authors subsequently reviewed, edited and approved	Performed the experiments|Wrote the paper	Investigation|Project administration|Writing - Original Draft|Writing - Review & Editing	YES
4048591	24894377	C. Ndondoki	2	were responsible for overall study coordination|was the study coordinator	were responsible for overall study coordination	-	Project administration	YES
4048591	24894377	C. Ndondoki	2	were responsible for overall study coordination|was the study coordinator	was the study coordinator	-	Project administration	YES
4048591	24894377	F Dabis	2	is the principal investigator of the west african iedea collaboration	is the principal investigator of the west african iedea collaboration	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
4048591	24894377	K Malateste	2	was in charge of managing the iedea west africa database	was in charge of managing the iedea west africa database	Contributed reagents/materials/analysis tools	Software	YES
4048591	24894377	V Leroy	2	sought funding for the study|were responsible for overall study coordination	sought funding for the study	-	Funding acquisition	YES
4048591	24894377	V Leroy	2	sought funding for the study|were responsible for overall study coordination	were responsible for overall study coordination	-	Project administration	YES
5468958	28659940	All the authors	2	agreed on the contents of the paper and declared no conflicting interest	agreed on the contents of the paper and declared no conflicting interest	-	-	NO
5468958	28659940	CA	2	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5468958	28659940	JJ	2	designed the research and wrote the manuscript	designed the research and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5468958	28659940	PP-D	2	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5468958	28659940	RC	2	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4400163	25880500	MFM	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400163	25880500	PR	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400163	25880500	PR	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400163	25880500	SL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4400163	25880500	SW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400163	25880500	SW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400163	25880500	SW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400163	25880500	SW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400163	25880500	XW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4400163	25880500	XZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
2377254	18416849	AT	2	conceived and designed the study, participated in the coordination, data collection, analysis and interpretation of the data, and the drafting and critical revision of the manuscript	conceived and designed the study, participated in the coordination, data collection, analysis and interpretation of the data, and the drafting and critical revision of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Project administration|Writing - Original Draft|Writing - Review & Editing	YES
2377254	18416849	All authors	2	revised the manuscript critically and read and approved the final version	revised the manuscript critically and read and approved the final version	Wrote the paper	Writing - Review & Editing	YES
2377254	18416849	CL	2	participated in the design of the study and the questionnaire and helped to collect the data and to draft the manuscript	participated in the design of the study and the questionnaire and helped to collect the data and to draft the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
2377254	18416849	FGW	2	assisted in the coordination of the study and carried out parts of the data collection from the medical files	assisted in the coordination of the study and carried out parts of the data collection from the medical files	Performed the experiments	Investigation|Project administration	YES
2377254	18416849	GM	2	participated in the design of the study and the questionnaire and assisted in the coordination of the study	participated in the design of the study and the questionnaire and assisted in the coordination of the study	Conceived and designed the experiments	Methodology|Project administration	YES
2377254	18416849	MAB	2	participated in the design of the study and the questionnaire, coordinated and carried out data collection, performed the statistical analysis, interpreted the data and drafted the manuscript	participated in the design of the study and the questionnaire, coordinated and carried out data collection, performed the statistical analysis, interpreted the data and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Project administration|Writing - Original Draft	YES
2377254	18416849	MC	2	participated in the design of the study and the questionnaire and assisted in the coordination of the study	participated in the design of the study and the questionnaire and assisted in the coordination of the study	Conceived and designed the experiments	Methodology|Project administration	YES
2377254	18416849	MM	2	participated in the design of the study and the questionnaire, assisted in the coordination of the study, carried out interviews and data collection, and interpreted the data	participated in the design of the study and the questionnaire, assisted in the coordination of the study, carried out interviews and data collection, and interpreted the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology|Project administration	YES
2377254	18416849	MZ	2	participated in the design of the study and the questionnaire and carried out interviews	participated in the design of the study and the questionnaire and carried out interviews	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
2377254	18416849	RNI	2	participated in the design and coordination of the study and critically revised the manuscript	participated in the design and coordination of the study and critically revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Review & Editing	YES
5469006	28659943	CH	2	helped in sampling and the measurements of physiological parameters	helped in sampling and the measurements of physiological parameters	Performed the experiments	Investigation	YES
5469006	28659943	CM	2	helped in drafting the manuscript and the interpretation of the results	helped in drafting the manuscript and the interpretation of the results	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5469006	28659943	DJ	2	helped in drafting the manuscript and the interpretation of the results	helped in drafting the manuscript and the interpretation of the results	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5469006	28659943	MA	2	helped in revising the manuscript and the responses to the comments	helped in revising the manuscript and the responses to the comments	Wrote the paper	Writing - Review & Editing	YES
5469006	28659943	TD	2	designed the experiment	designed the experiment	Conceived and designed the experiments	Methodology	YES
5469006	28659943	YF	2	designed the experiment|conducted the study, collected and analyzed the data, and prepared the draft	designed the experiment	Conceived and designed the experiments	Methodology	YES
5469006	28659943	YF	2	designed the experiment|conducted the study, collected and analyzed the data, and prepared the draft	conducted the study, collected and analyzed the data, and prepared the draft	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5469006	28659943	YY	2	helped in sampling and the measurements of physiological parameters	helped in sampling and the measurements of physiological parameters	Performed the experiments	Investigation	YES
5469006	28659943	ZH	2	designed the experiment	designed the experiment	Conceived and designed the experiments	Methodology	YES
5469006	28659943	ZT	2	designed the experiment	designed the experiment	Conceived and designed the experiments	Methodology	YES
4049128	24909561	AA	2	designed the study|performed the test with the immunoassay|drafted the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
4049128	24909561	AA	2	designed the study|performed the test with the immunoassay|drafted the manuscript	performed the test with the immunoassay	Performed the experiments	Investigation	YES
4049128	24909561	AA	2	designed the study|performed the test with the immunoassay|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4049128	24909561	ABA	2	conceived the study|designed the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4049128	24909561	ABA	2	conceived the study|designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
4049128	24909561	All authors	2	critically reviewed and approved the manuscript	critically reviewed and approved the manuscript	Wrote the paper	Writing - Review & Editing	YES
4049128	24909561	PK	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5096333	27809786	BTB	2	reviewed this manuscript for language improvement	reviewed this manuscript for language improvement	Wrote the paper	Writing - Review & Editing	YES
5096333	27809786	BY	2	generated the cdna libraries|participated in experiments and data analysis	generated the cdna libraries	Performed the experiments	Investigation	YES
5096333	27809786	BY	2	generated the cdna libraries|participated in experiments and data analysis	participated in experiments and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5096333	27809786	EL	2	designed the work and wrote the manuscript	designed the work and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
5096333	27809786	HS	2	designed the work and wrote the manuscript	designed the work and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
5096333	27809786	JZ	2	participated in experiments and data analysis	participated in experiments and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5096333	27809786	QX	2	participated in experiments and data analysis	participated in experiments and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5096333	27809786	QZ	2	participated in experiments and data analysis	participated in experiments and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5096333	27809786	SZ	2	participated in experiments and data analysis	participated in experiments and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5096333	27809786	WH	2	participated in experiments and data analysis	participated in experiments and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4434229	26097845	Alessia Finotti	2	was the principal investigator, took primary responsibility for the paper, performed experiments, contributed to analyzing data and to writing the paper, and finally approved the version to be published	was the principal investigator, took primary responsibility for the paper, performed experiments, contributed to analyzing data and to writing the paper, and finally approved the version to be published	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Funding acquisition|Investigation|Resources|Writing - Original Draft	YES
4434229	26097845	Cristina Zuccato	2	participated in performing the experiments	participated in performing the experiments	Performed the experiments	Investigation	YES
4434229	26097845	Enrica Fabbri	2	participated in performing the experiments	participated in performing the experiments	Performed the experiments	Investigation	YES
4434229	26097845	Fiorella Altruda	2	contributed to microinjection procedure and critically reviewed the paper	contributed to microinjection procedure and critically reviewed the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4434229	26097845	Francesca Salvatori	2	participated in performing the experiments	participated in performing the experiments	Performed the experiments	Investigation	YES
4434229	26097845	Gianni Carandina	2	participated in analyzing the mice hematological parameters	participated in analyzing the mice hematological parameters	Analyzed the data	Formal analysis	YES
4434229	26097845	Giulia Breveglieri	2	performed experiments and contributed to analyzing data and to writing the paper	performed experiments and contributed to analyzing data and to writing the paper	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft	YES
4434229	26097845	Giulia Montagner	2	participated in performing the experiments	participated in performing the experiments	Performed the experiments	Investigation	YES
4434229	26097845	Ilaria Lampronti	2	participated in performing the experiments	participated in performing the experiments	Performed the experiments	Investigation	YES
4434229	26097845	Irene Mancini	2	participated in performing the experiments	participated in performing the experiments	Performed the experiments	Investigation	YES
4434229	26097845	Laura Breda	2	produced the t9w lentiviral vector and critically reviewed the paper	produced the t9w lentiviral vector and critically reviewed the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4434229	26097845	Lucia C. Cosenza	2	participated in performing the experiments	participated in performing the experiments	Performed the experiments	Investigation	YES
4434229	26097845	Michele Rubini	2	collaborated for fish experiments	collaborated for fish experiments	-	-	NO
4434229	26097845	Monica Borgatti	2	participated in performing the experiments	participated in performing the experiments	Performed the experiments	Investigation	YES
4434229	26097845	Nicoletta Bianchi	2	participated in performing the experiments	participated in performing the experiments	Performed the experiments	Investigation	YES
4434229	26097845	Sharmila Fagoonee	2	contributed to microinjection procedure and critically reviewed the paper	contributed to microinjection procedure and critically reviewed the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4434229	26097845	Stefano Rivella	2	produced the t9w lentiviral vector and critically reviewed the paper	produced the t9w lentiviral vector and critically reviewed the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4434229	26097845	Vincenzo Aiello	2	collaborated for fish experiments	collaborated for fish experiments	-	-	NO
4400164	25880081	AO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400164	25880081	AO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400164	25880081	AO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400164	25880081	AO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400164	25880081	AO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400164	25880081	BF	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4400164	25880081	DB	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400164	25880081	HE	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400164	25880081	IM	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4400164	25880081	MS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400164	25880081	MVPG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4400164	25880081	RA	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4400164	25880081	UE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400164	25880081	UE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400164	25880081	UE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400164	25880081	UE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400164	25880081	UE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2391156	18442415	AL	2	carried out the labwork and drafted the manuscript	carried out the labwork and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
2391156	18442415	LD	2	prepared the clinical reports for the ird patients	prepared the clinical reports for the ird patients	-	-	NO
2391156	18442415	MAF	2	conceived and designed the study, and helped draft the manuscript	conceived and designed the study, and helped draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
2391156	18442415	PP	2	helped to draft the manuscript	helped to draft the manuscript	Wrote the paper	Writing - Original Draft	YES
4400165	25880369	BF	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400165	25880369	CC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400165	25880369	CC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400165	25880369	CC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400165	25880369	CMD	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400165	25880369	GD	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400165	25880369	GD	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400165	25880369	GD	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400165	25880369	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400165	25880369	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400165	25880369	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400165	25880369	MBP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400165	25880369	MBP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400165	25880369	MBP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400165	25880369	MBP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400165	25880369	RC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400165	25880369	RC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400165	25880369	RC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5469044	28659963	JL	2	contributed to study conception and design, collection and/or assembly of data, data analysis and interpretation, and manuscript writing	contributed to study conception and design, collection and/or assembly of data, data analysis and interpretation, and manuscript writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
5469044	28659963	JX	2	prepared samples, collected and/or assembled data, and analyzed and interpreted data	prepared samples, collected and/or assembled data, and analyzed and interpreted data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5469044	28659963	YC	2	contributed to study conception and design, collection and/or assembly of data, data analysis and interpretation, and manuscript writing	contributed to study conception and design, collection and/or assembly of data, data analysis and interpretation, and manuscript writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
5469044	28659963	YM	2	prepared samples, collected and/or assembled data, and analyzed and interpreted data	prepared samples, collected and/or assembled data, and analyzed and interpreted data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5469044	28659963	YS	2	prepared samples, collected and/or assembled data, and analyzed and interpreted data	prepared samples, collected and/or assembled data, and analyzed and interpreted data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5469044	28659963	YZ	2	prepared samples, collected and/or assembled data, and analyzed and interpreted data	prepared samples, collected and/or assembled data, and analyzed and interpreted data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
2426711	18522743	AM	2	provided c14, participated in the design of the study, and helped draft the manuscript	provided c14, participated in the design of the study, and helped draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
2426711	18522743	BG	2	provided c14, participated in the design of the study, and helped draft the manuscript	provided c14, participated in the design of the study, and helped draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
2426711	18522743	DNA	2	and p24 elisa	and p24 elisa	Performed the experiments	Investigation	YES
2426711	18522743	HS	2	carried out differentiation and infection of dendritic cells, macrophages and t cells, isolation of t cells, hiv-1 transfer assays, cytotoxicity assay, confocal microscopy assay, interpretation rabbit vaginal irritation model and helped draft the manuscript	carried out differentiation and infection of dendritic cells, macrophages and t cells, isolation of t cells, hiv-1 transfer assays, cytotoxicity assay, confocal microscopy assay, interpretation rabbit vaginal irritation model and helped draft the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
2426711	18522743	MAJ	2	carried out differentiation and infection of dendritic cells, macrophages and t cells, isolation of t cells, hiv-1 transfer assays, cytotoxicity assay, confocal microscopy assay, interpretation rabbit vaginal irritation model and helped draft the manuscript	carried out differentiation and infection of dendritic cells, macrophages and t cells, isolation of t cells, hiv-1 transfer assays, cytotoxicity assay, confocal microscopy assay, interpretation rabbit vaginal irritation model and helped draft the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5097350	27814678	AYL	PLoS52	helped with the field experiments|contributed reagents and materials	helped with the field experiments	Performed the experiments	Investigation	YES
5097350	27814678	AYL	PLoS52	helped with the field experiments|contributed reagents and materials	contributed reagents and materials	Contributed reagents/materials/analysis tools	Resources	YES
5097350	27814678	BCZ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5097350	27814678	GQ	PLoS52	contributed reagents and materials	contributed reagents and materials	Contributed reagents/materials/analysis tools	Resources	YES
5097350	27814678	HHS	PLoS52	contributed reagents and materials	contributed reagents and materials	Contributed reagents/materials/analysis tools	Resources	YES
5097350	27814678	HQZ	PLoS52	contributed reagents and materials	contributed reagents and materials	Contributed reagents/materials/analysis tools	Resources	YES
5097350	27814678	JWG	PLoS52	contributed reagents and materials	contributed reagents and materials	Contributed reagents/materials/analysis tools	Resources	YES
5097350	27814678	JWL	PLoS52	helped with the field experiments|contributed reagents and materials	helped with the field experiments	Performed the experiments	Investigation	YES
5097350	27814678	JWL	PLoS52	helped with the field experiments|contributed reagents and materials	contributed reagents and materials	Contributed reagents/materials/analysis tools	Resources	YES
5097350	27814678	LZ	PLoS52	contributed reagents and materials	contributed reagents and materials	Contributed reagents/materials/analysis tools	Resources	YES
5097350	27814678	QWL	PLoS52	helped with data analyses	helped with data analyses	Analyzed the data	Formal analysis	YES
5097350	27814678	SQL	PLoS52	helped with data analyses	helped with data analyses	Analyzed the data	Formal analysis	YES
5097350	27814678	TTC	PLoS52	contributed reagents and materials	contributed reagents and materials	Contributed reagents/materials/analysis tools	Resources	YES
5097350	27814678	TW	PLoS52	contributed reagents and materials	contributed reagents and materials	Contributed reagents/materials/analysis tools	Resources	YES
5097350	27814678	WKG	PLoS52	contributed reagents and materials	contributed reagents and materials	Contributed reagents/materials/analysis tools	Resources	YES
5097350	27814678	WTL	PLoS52	helped with data analyses	helped with data analyses	Analyzed the data	Formal analysis	YES
5097350	27814678	YLY	PLoS52	conceived the study|revised the manuscript|contributed reagents and materials	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5097350	27814678	YLY	PLoS52	conceived the study|revised the manuscript|contributed reagents and materials	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5097350	27814678	YLY	PLoS52	conceived the study|revised the manuscript|contributed reagents and materials	contributed reagents and materials	Contributed reagents/materials/analysis tools	Resources	YES
5097350	27814678	YZS	PLoS52	performed the experiments|conducted the data analysis and drafted the manuscript|contributed reagents and materials	performed the experiments	Performed the experiments	Investigation	YES
5097350	27814678	YZS	PLoS52	performed the experiments|conducted the data analysis and drafted the manuscript|contributed reagents and materials	conducted the data analysis and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5097350	27814678	YZS	PLoS52	performed the experiments|conducted the data analysis and drafted the manuscript|contributed reagents and materials	contributed reagents and materials	Contributed reagents/materials/analysis tools	Resources	YES
5097350	27814678	ZZ	PLoS52	helped with data analyses	helped with data analyses	Analyzed the data	Formal analysis	YES
4056161	24925044	AJvR	PLoS52	collected the data	collected the data	Performed the experiments	Investigation	YES
4056161	24925044	AL	PLoS52	collected the data	collected the data	Performed the experiments	Investigation	YES
4056161	24925044	All authors	PLoS52	contributed to interpretation of results and drafting of the manuscript	contributed to interpretation of results and drafting of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4056161	24925044	BE	PLoS52	collected the data	collected the data	Performed the experiments	Investigation	YES
4056161	24925044	EL	PLoS52	collected the data	collected the data	Performed the experiments	Investigation	YES
4056161	24925044	KO	PLoS52	collected the data|analyzed the data	collected the data	Performed the experiments	Investigation	YES
4056161	24925044	KO	PLoS52	collected the data|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
4056161	24925044	NG	PLoS52	collected the data	collected the data	Performed the experiments	Investigation	YES
4056161	24925044	RG	PLoS52	collected the data	collected the data	Performed the experiments	Investigation	YES
4056161	24925044	SI	PLoS52	collected the data|analyzed the data	collected the data	Performed the experiments	Investigation	YES
4056161	24925044	SI	PLoS52	collected the data|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
4056161	24925044	TH	PLoS52	collected the data	collected the data	Performed the experiments	Investigation	YES
3850244	24215616	All authors	2	have given approval to the final version of the manuscript	have given approval to the final version of the manuscript	-	-	NO
2438438	18534033	Margo Camel	2	in some of the experiments	in some of the experiments	-	-	NO
5469070	28659941	GD	2	collected literature and wrote the manuscript	collected literature and wrote the manuscript	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5469070	28659941	JP	2	collected literature and wrote the manuscript	collected literature and wrote the manuscript	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5469070	28659941	KB	2	edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5097351	27814670	CM	2	conceived the project idea	conceived the project idea	Conceived and designed the experiments	Conceptualization	YES
5097351	27814670	GM	2	conceived the project idea|wrote the manuscript	conceived the project idea	Conceived and designed the experiments	Conceptualization	YES
5097351	27814670	GM	2	conceived the project idea|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5097351	27814670	GS	2	edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5097351	27814670	LF	2	edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5097351	27814670	LL	2	conceived the project idea|performed data analysis|wrote the manuscript	conceived the project idea	Conceived and designed the experiments	Conceptualization	YES
5097351	27814670	LL	2	conceived the project idea|performed data analysis|wrote the manuscript	performed data analysis	Analyzed the data	Formal analysis	YES
5097351	27814670	LL	2	conceived the project idea|performed data analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5097351	27814670	NS	2	conceived the project idea|edited the manuscript	conceived the project idea	Conceived and designed the experiments	Conceptualization	YES
5097351	27814670	NS	2	conceived the project idea|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5097351	27814670	PS	2	edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5097351	27814670	RB	2	performed data analysis	performed data analysis	Analyzed the data	Formal analysis	YES
5097351	27814670	RS	2	performed data analysis	performed data analysis	Analyzed the data	Formal analysis	YES
4027954	24646070	M.W.L.	2	contributed equally to this work	contributed equally to this work	-	-	NO
4027954	24646070	Z.D.	2	contributed equally to this work	contributed equally to this work	-	-	NO
2443165	18570675	All authors	2	contributed to the writing, read and approved the final manuscript	contributed to the writing, read and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
2443165	18570675	BMN	2	conceived the study|coordinated data collection and performed laboratory, data analyses and interpretation of results	conceived the study	Conceived and designed the experiments	Conceptualization	YES
2443165	18570675	BMN	2	conceived the study|coordinated data collection and performed laboratory, data analyses and interpretation of results	coordinated data collection and performed laboratory, data analyses and interpretation of results	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Project administration	YES
2443165	18570675	CHH	2	conceived the study|participated in study design, interpretation of results	conceived the study	Conceived and designed the experiments	Conceptualization	YES
2443165	18570675	CHH	2	conceived the study|participated in study design, interpretation of results	participated in study design, interpretation of results	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
2443165	18570675	FM	2	conceived the study|participated in laboratory analysis|participated in study design, interpretation of results	conceived the study	Conceived and designed the experiments	Conceptualization	YES
2443165	18570675	FM	2	conceived the study|participated in laboratory analysis|participated in study design, interpretation of results	participated in laboratory analysis	Performed the experiments	Investigation	YES
2443165	18570675	FM	2	conceived the study|participated in laboratory analysis|participated in study design, interpretation of results	participated in study design, interpretation of results	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
2443165	18570675	GB	2	participated in study design	participated in study design	Conceived and designed the experiments	Methodology	YES
2443165	18570675	KIK	2	participated in laboratory analysis	participated in laboratory analysis	Performed the experiments	Investigation	YES
4400171	25879227	RT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400171	25879227	RT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400171	25879227	RT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400171	25879227	RT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400171	25879227	SKP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400171	25879227	SKP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400171	25879227	SKP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400171	25879227	SKP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4057784	24929097	CM	PLoS52	designed the study|undertook data collection|analyzed the data|wrote the first draft of the manuscript|reviewed and approved the final manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
4057784	24929097	CM	PLoS52	designed the study|undertook data collection|analyzed the data|wrote the first draft of the manuscript|reviewed and approved the final manuscript	undertook data collection	Performed the experiments	Investigation	YES
4057784	24929097	CM	PLoS52	designed the study|undertook data collection|analyzed the data|wrote the first draft of the manuscript|reviewed and approved the final manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
4057784	24929097	CM	PLoS52	designed the study|undertook data collection|analyzed the data|wrote the first draft of the manuscript|reviewed and approved the final manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
4057784	24929097	CM	PLoS52	designed the study|undertook data collection|analyzed the data|wrote the first draft of the manuscript|reviewed and approved the final manuscript	reviewed and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4057784	24929097	DGL	PLoS52	reviewed and approved the final manuscript	reviewed and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4057784	24929097	ELC	PLoS52	reviewed and approved the final manuscript	reviewed and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4057784	24929097	MT	PLoS52	designed the study|reviewed and approved the final manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
4057784	24929097	MT	PLoS52	designed the study|reviewed and approved the final manuscript	reviewed and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4057784	24929097	NF	PLoS52	reviewed and approved the final manuscript	reviewed and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4057784	24929097	PGG	PLoS52	designed the study|reviewed and approved the final manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
4057784	24929097	PGG	PLoS52	designed the study|reviewed and approved the final manuscript	reviewed and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4057784	24929097	PM	PLoS52	designed the study|analyzed the data|reviewed and approved the final manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
4057784	24929097	PM	PLoS52	designed the study|analyzed the data|reviewed and approved the final manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
4057784	24929097	PM	PLoS52	designed the study|analyzed the data|reviewed and approved the final manuscript	reviewed and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4057784	24929097	SBS	PLoS52	reviewed and approved the final manuscript	reviewed and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
3856771	24007203	All authors	2	have given approval to the final version of the manuscript	have given approval to the final version of the manuscript	-	-	NO
5469071	28659933	CS	PLoS52	did the bioinformatics analysis	did the bioinformatics analysis	-	Formal analysis	YES
5469071	28659933	HW	PLoS52	did the bioinformatics analysis	did the bioinformatics analysis	-	Formal analysis	YES
5469071	28659933	JY	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5469071	28659933	LZ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5469071	28659933	WY	PLoS52	did the bioinformatics analysis	did the bioinformatics analysis	-	Formal analysis	YES
5469071	28659933	XL	PLoS52	conceived the study|designed the experiments|wrote the article	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5469071	28659933	XL	PLoS52	conceived the study|designed the experiments|wrote the article	designed the experiments	Conceived and designed the experiments	Methodology	YES
5469071	28659933	XL	PLoS52	conceived the study|designed the experiments|wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
5469071	28659933	XW	PLoS52	did the bioinformatics analysis	did the bioinformatics analysis	-	Formal analysis	YES
5469071	28659933	YW	PLoS52	conceived the study|designed the experiments|performed the experiments|wrote the article	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5469071	28659933	YW	PLoS52	conceived the study|designed the experiments|performed the experiments|wrote the article	designed the experiments	Conceived and designed the experiments	Methodology	YES
5469071	28659933	YW	PLoS52	conceived the study|designed the experiments|performed the experiments|wrote the article	performed the experiments	Performed the experiments	Investigation	YES
5469071	28659933	YW	PLoS52	conceived the study|designed the experiments|performed the experiments|wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
5469071	28659933	ZS	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5097354	27814679	EW	PLoS52	performed the experiments|designed the study, analyzed the data and wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5097354	27814679	EW	PLoS52	performed the experiments|designed the study, analyzed the data and wrote the manuscript	designed the study, analyzed the data and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5097354	27814679	KV	PLoS52	designed the study, analyzed the data and wrote the manuscript	designed the study, analyzed the data and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
2478721	18593479	DL	2	helped to draft and revise the manuscript	helped to draft and revise the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
2478721	18593479	JSH	2	conceived of the study, participated in its design and performance, and drafted the initial manuscript	conceived of the study, participated in its design and performance, and drafted the initial manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Writing - Original Draft	YES
2478721	18593479	KB	2	participated in study performance and data collection	participated in study performance and data collection	Performed the experiments	Investigation	YES
2478721	18593479	SF	2	participated in study performance and data collection	participated in study performance and data collection	Performed the experiments	Investigation	YES
2478721	18593479	WCM	2	helped to draft and revise the manuscript	helped to draft and revise the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3362016	22675272	All authors	2	have read and approved the final manuscript	have read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
3362016	22675272	EDW	2	executed the study, analysed the data, and drafted the paper	executed the study, analysed the data, and drafted the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3362016	22675272	H. Spapen	2	cowrote the paper	cowrote the paper	Wrote the paper	Writing - Original Draft	YES
3362016	22675272	L. Huyghens	2	was responsible for the provision of practical support	was responsible for the provision of practical support	-	-	NO
3362016	22675272	P. M. Honore	2	cowrote the paper	cowrote the paper	Wrote the paper	Writing - Original Draft	YES
3362016	22675272	S. Mattens	2	assisted with data collection	assisted with data collection	Performed the experiments	Investigation	YES
3362016	22675272	T. Rose	2	cowrote the paper	cowrote the paper	Wrote the paper	Writing - Original Draft	YES
3362016	22675272	The authors	2	declare no conflict of interest	declare no conflict of interest	-	-	NO
4400172	25880357	AM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4400172	25880357	AM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400172	25880357	AP	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400172	25880357	AP	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400172	25880357	MP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400172	25880357	MP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400172	25880357	MP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400172	25880357	MP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400172	25880357	MP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400172	25880357	RD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400172	25880357	RD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400172	25880357	RD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400172	25880357	RD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400172	25880357	RD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400172	25880357	RF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400172	25880357	RF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400172	25880357	RF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400172	25880357	RF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400172	25880357	RF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400172	25880357	TM	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400172	25880357	TM	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5097360	27814676	BSM	2	conceived and developed the algorithms for the preprocessing of chip-nexus data	conceived and developed the algorithms for the preprocessing of chip-nexus data	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Data curation|Software	YES
5097360	27814676	JH	2	assisted with the analysis in the paper and provided biological insights into the chip-nexus procedure	assisted with the analysis in the paper and provided biological insights into the chip-nexus procedure	Performed the experiments	Investigation	YES
5097360	27814676	JIS	2	assisted with the analysis in the paper and provided biological insights into the chip-nexus procedure	assisted with the analysis in the paper and provided biological insights into the chip-nexus procedure	Performed the experiments	Investigation	YES
5097360	27814676	MT	2	assisted with the analysis in the paper and provided biological insights into the chip-nexus procedure	assisted with the analysis in the paper and provided biological insights into the chip-nexus procedure	Performed the experiments	Investigation	YES
5097360	27814676	PH	2	conceived and developed the methods for the estimation of the protected-region width and chip-nexus peak calling, conducted the reproducibility analysis, and wrote the manuscript	conceived and developed the methods for the estimation of the protected-region width and chip-nexus peak calling, conducted the reproducibility analysis, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Validation|Writing - Original Draft	YES
5097360	27814676	PNR	2	helped develop the algorithm, supervised the analysis, and wrote the manuscript	helped develop the algorithm, supervised the analysis, and wrote the manuscript	Contributed reagents/materials/analysis tools|Wrote the paper	Software|Supervision|Writing - Original Draft	YES
5097360	27814676	SR	2	conceived and developed the algorithms for the preprocessing of chip-nexus data	conceived and developed the algorithms for the preprocessing of chip-nexus data	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Data curation|Software	YES
5469152	28659958	AJ	2	managed the project	managed the project	-	Project administration	YES
5469152	28659958	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5469152	28659958	YG	2	edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5469152	28659958	YL	2	designed experiments, collected the data, prepared the figures, and wrote the manuscript|edited the manuscript	designed experiments, collected the data, prepared the figures, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Visualization|Writing - Original Draft	YES
5469152	28659958	YL	2	designed experiments, collected the data, prepared the figures, and wrote the manuscript|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
4062879	24942364	AIDS	2	was responsible for the section entitled optimization of antiretroviral therapy after virologic suppression	was responsible for the section entitled optimization of antiretroviral therapy after virologic suppression	-	-	NO
4062879	24942364	AMT	2	was responsible for all pharmacological issues in the manuscript, was responsible for the section entitled generic drugs and medical and economic considerations, and drafted table 3	was responsible for all pharmacological issues in the manuscript, was responsible for the section entitled generic drugs and medical and economic considerations, and drafted table 3	Wrote the paper	Writing - Original Draft	YES
4062879	24942364	All authors	2	have been involved in drafting the manuscript and revising it critically for its whole content|all have read and approved the final manuscript	have been involved in drafting the manuscript and revising it critically for its whole content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4062879	24942364	All authors	2	have been involved in drafting the manuscript and revising it critically for its whole content|all have read and approved the final manuscript	all have read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4062879	24942364	BH	2	coordinated the writing group, drafted the when to start and what to start sections, was responsible for harmonizing the whole manuscript, and checked the accuracy of all literature sources|endorses responsibility for the article content	coordinated the writing group, drafted the when to start and what to start sections, was responsible for harmonizing the whole manuscript, and checked the accuracy of all literature sources	Wrote the paper	Project administration|Writing - Original Draft	YES
4062879	24942364	BH	2	coordinated the writing group, drafted the when to start and what to start sections, was responsible for harmonizing the whole manuscript, and checked the accuracy of all literature sources|endorses responsibility for the article content	endorses responsibility for the article content	-	-	NO
4062879	24942364	CD	2	were responsible for all virologic aspects of the manuscript	were responsible for all virologic aspects of the manuscript	-	-	NO
4062879	24942364	CG	2	was responsible for drafting the section entitled specific situations for the choice of the first antiretroviral therapy	was responsible for drafting the section entitled specific situations for the choice of the first antiretroviral therapy	Wrote the paper	Writing - Original Draft	YES
4062879	24942364	CR	2	were responsible for all virologic aspects of the manuscript	were responsible for all virologic aspects of the manuscript	-	-	NO
4062879	24942364	DR	2	was responsible for the section entitled optimization of antiretroviral therapy after virologic suppression	was responsible for the section entitled optimization of antiretroviral therapy after virologic suppression	-	-	NO
4062879	24942364	FB	2	drafted table 2 and was responsible for all aspects of the manuscript that were related to patients clinical management and follow-up	drafted table 2 and was responsible for all aspects of the manuscript that were related to patients clinical management and follow-up	Wrote the paper	Writing - Original Draft	YES
4062879	24942364	PD	2	was responsible for drafting the virologic failure section	was responsible for drafting the virologic failure section	Wrote the paper	Writing - Original Draft	YES
4062879	24942364	PM	2	supervised the finalization of the manuscript and endorses responsibility for its content	supervised the finalization of the manuscript and endorses responsibility for its content	Wrote the paper	Supervision|Writing - Review & Editing	YES
4436445	26075276	Agathe Goubard	2	provided the laboratory data	provided the laboratory data	Contributed reagents/materials/analysis tools	Resources	YES
4436445	26075276	All authors	2	participated in the writing of the final version of the paper	participated in the writing of the final version of the paper	Wrote the paper	Writing - Original Draft	YES
4436445	26075276	Catherine Cordonnier	2	designed the study|drafted the paper	designed the study	Conceived and designed the experiments	Methodology	YES
4436445	26075276	Catherine Cordonnier	2	designed the study|drafted the paper	drafted the paper	Wrote the paper	Writing - Original Draft	YES
4436445	26075276	Hicham El Maaroufi	2	collected the clinical data|drafted the paper	collected the clinical data	Performed the experiments	Investigation	YES
4436445	26075276	Hicham El Maaroufi	2	collected the clinical data|drafted the paper	drafted the paper	Wrote the paper	Writing - Original Draft	YES
4436445	26075276	Kamal Doghmi	2	participated in the result analysis and interpretation	participated in the result analysis and interpretation	Analyzed the data	Formal analysis	YES
4436445	26075276	Michael Schwarzinger	2	designed the study|run the statistical analysis|drafted the paper	designed the study	Conceived and designed the experiments	Methodology	YES
4436445	26075276	Michael Schwarzinger	2	designed the study|run the statistical analysis|drafted the paper	run the statistical analysis	Analyzed the data	Formal analysis	YES
4436445	26075276	Michael Schwarzinger	2	designed the study|run the statistical analysis|drafted the paper	drafted the paper	Wrote the paper	Writing - Original Draft	YES
4436445	26075276	Mohamed Mikdame	2	participated in the result analysis and interpretation	participated in the result analysis and interpretation	Analyzed the data	Formal analysis	YES
4436445	26075276	Patrick Legrand	2	designed the study|provided the laboratory data	designed the study	Conceived and designed the experiments	Methodology	YES
4436445	26075276	Patrick Legrand	2	designed the study|provided the laboratory data	provided the laboratory data	Contributed reagents/materials/analysis tools	Resources	YES
4436445	26075276	Sebastien Maury	2	participated in the result analysis and interpretation	participated in the result analysis and interpretation	Analyzed the data	Formal analysis	YES
2483717	18544167	FACS	2	as well as kinase assays	as well as kinase assays	Performed the experiments	Investigation	YES
2483717	18544167	FK	2	also provided the overall direction and the funding for the project	also provided the overall direction and the funding for the project	-	Funding acquisition|Supervision	YES
2483717	18544167	KKH	2	provided the day to day leadership and direction for the project	provided the day to day leadership and direction for the project	-	Supervision	YES
2483717	18544167	WW	2	provided the day to day leadership and direction for the project	provided the day to day leadership and direction for the project	-	Supervision	YES
4400173	25879956	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Critically revised the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400173	25879956	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Critically revised the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4400173	25879956	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Critically revised the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400173	25879956	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Critically revised the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400173	25879956	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Critically revised the manuscript	Critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4400173	25879956	EB	PLoS5	Conceived and designed the experiments|Performed the experiments|Critically revised the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400173	25879956	EB	PLoS5	Conceived and designed the experiments|Performed the experiments|Critically revised the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4400173	25879956	EB	PLoS5	Conceived and designed the experiments|Performed the experiments|Critically revised the manuscript	Critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4400173	25879956	EV	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Critically revised the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400173	25879956	EV	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Critically revised the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400173	25879956	EV	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Critically revised the manuscript	Critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4400173	25879956	FM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400173	25879956	FM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400173	25879956	FM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400173	25879956	FM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400173	25879956	HB	PLoS5	Conceived and designed the experiments|Critically revised the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400173	25879956	HB	PLoS5	Conceived and designed the experiments|Critically revised the manuscript	Critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4400173	25879956	ME	PLoS5	Performed the experiments|Critically revised the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4400173	25879956	ME	PLoS5	Performed the experiments|Critically revised the manuscript	Critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4400173	25879956	NV	PLoS5	Contributed reagents/materials/analysis tools|Critically revised the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400173	25879956	NV	PLoS5	Contributed reagents/materials/analysis tools|Critically revised the manuscript	Critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4400173	25879956	PO	PLoS5	Performed the experiments|Critically revised the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4400173	25879956	PO	PLoS5	Performed the experiments|Critically revised the manuscript	Critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4400173	25879956	RB	PLoS5	Performed the experiments|Critically revised the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4400173	25879956	RB	PLoS5	Performed the experiments|Critically revised the manuscript	Critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4400173	25879956	RC	PLoS5	Performed the experiments|Critically revised the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4400173	25879956	RC	PLoS5	Performed the experiments|Critically revised the manuscript	Critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4400173	25879956	RW	PLoS5	Performed the experiments|Critically revised the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4400173	25879956	RW	PLoS5	Performed the experiments|Critically revised the manuscript	Critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4400173	25879956	SA	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Critically revised the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400173	25879956	SA	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Critically revised the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400173	25879956	SA	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Critically revised the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400173	25879956	SA	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Critically revised the manuscript	Critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
2495004	18647392	KG	2	participated in the design of study, acquisition of data, analysis and interpretation of data, drafting the article, and final approval of this version	participated in the design of study, acquisition of data, analysis and interpretation of data, drafting the article, and final approval of this version	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
2495004	18647392	MMS	2	participated in the design of study, acquisition of data, interpretation of data, and drafting the article	participated in the design of study, acquisition of data, interpretation of data, and drafting the article	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
2495004	18647392	PK	2	participated in acquisition of data, analysis and interpretation of data, and drafting the article	participated in acquisition of data, analysis and interpretation of data, and drafting the article	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4065309	24950749	CC	2	acquired data|contributed to the writing and/or revision|agreed with manuscript results and conclusions	acquired data	Performed the experiments	Investigation	YES
4065309	24950749	CC	2	acquired data|contributed to the writing and/or revision|agreed with manuscript results and conclusions	contributed to the writing and/or revision	Wrote the paper	Writing - Review & Editing	YES
4065309	24950749	CC	2	acquired data|contributed to the writing and/or revision|agreed with manuscript results and conclusions	agreed with manuscript results and conclusions	-	-	NO
4065309	24950749	CS	2	acquired data|contributed to the writing and/or revision|agreed with manuscript results and conclusions	acquired data	Performed the experiments	Investigation	YES
4065309	24950749	CS	2	acquired data|contributed to the writing and/or revision|agreed with manuscript results and conclusions	contributed to the writing and/or revision	Wrote the paper	Writing - Review & Editing	YES
4065309	24950749	CS	2	acquired data|contributed to the writing and/or revision|agreed with manuscript results and conclusions	agreed with manuscript results and conclusions	-	-	NO
4065309	24950749	EW	2	acquired data|contributed to the writing and/or revision|agreed with manuscript results and conclusions	acquired data	Performed the experiments	Investigation	YES
4065309	24950749	EW	2	acquired data|contributed to the writing and/or revision|agreed with manuscript results and conclusions	contributed to the writing and/or revision	Wrote the paper	Writing - Review & Editing	YES
4065309	24950749	EW	2	acquired data|contributed to the writing and/or revision|agreed with manuscript results and conclusions	agreed with manuscript results and conclusions	-	-	NO
4065309	24950749	LF	2	acquired data|contributed to the writing and/or revision|agreed with manuscript results and conclusions	acquired data	Performed the experiments	Investigation	YES
4065309	24950749	LF	2	acquired data|contributed to the writing and/or revision|agreed with manuscript results and conclusions	contributed to the writing and/or revision	Wrote the paper	Writing - Review & Editing	YES
4065309	24950749	LF	2	acquired data|contributed to the writing and/or revision|agreed with manuscript results and conclusions	agreed with manuscript results and conclusions	-	-	NO
4065309	24950749	LV	2	acquired data|contributed to the writing and/or revision|agreed with manuscript results and conclusions	acquired data	Performed the experiments	Investigation	YES
4065309	24950749	LV	2	acquired data|contributed to the writing and/or revision|agreed with manuscript results and conclusions	contributed to the writing and/or revision	Wrote the paper	Writing - Review & Editing	YES
4065309	24950749	LV	2	acquired data|contributed to the writing and/or revision|agreed with manuscript results and conclusions	agreed with manuscript results and conclusions	-	-	NO
4065309	24950749	MCV	2	conceived and designed the manuscript|acquired data|contributed to the writing and/or revision|agreed with manuscript results and conclusions	conceived and designed the manuscript	Conceived and designed the experiments	Conceptualization	YES
4065309	24950749	MCV	2	conceived and designed the manuscript|acquired data|contributed to the writing and/or revision|agreed with manuscript results and conclusions	acquired data	Performed the experiments	Investigation	YES
4065309	24950749	MCV	2	conceived and designed the manuscript|acquired data|contributed to the writing and/or revision|agreed with manuscript results and conclusions	contributed to the writing and/or revision	Wrote the paper	Writing - Review & Editing	YES
4065309	24950749	MCV	2	conceived and designed the manuscript|acquired data|contributed to the writing and/or revision|agreed with manuscript results and conclusions	agreed with manuscript results and conclusions	-	-	NO
4065309	24950749	MF	2	conceived and designed the manuscript|acquired data|prepared the first draft of the manuscript|contributed to the writing and/or revision|agreed with manuscript results and conclusions	conceived and designed the manuscript	Conceived and designed the experiments	Conceptualization	YES
4065309	24950749	MF	2	conceived and designed the manuscript|acquired data|prepared the first draft of the manuscript|contributed to the writing and/or revision|agreed with manuscript results and conclusions	acquired data	Performed the experiments	Investigation	YES
4065309	24950749	MF	2	conceived and designed the manuscript|acquired data|prepared the first draft of the manuscript|contributed to the writing and/or revision|agreed with manuscript results and conclusions	prepared the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
4065309	24950749	MF	2	conceived and designed the manuscript|acquired data|prepared the first draft of the manuscript|contributed to the writing and/or revision|agreed with manuscript results and conclusions	contributed to the writing and/or revision	Wrote the paper	Writing - Review & Editing	YES
4065309	24950749	MF	2	conceived and designed the manuscript|acquired data|prepared the first draft of the manuscript|contributed to the writing and/or revision|agreed with manuscript results and conclusions	agreed with manuscript results and conclusions	-	-	NO
4065309	24950749	MTE	2	acquired data|contributed to the writing and/or revision|agreed with manuscript results and conclusions	acquired data	Performed the experiments	Investigation	YES
4065309	24950749	MTE	2	acquired data|contributed to the writing and/or revision|agreed with manuscript results and conclusions	contributed to the writing and/or revision	Wrote the paper	Writing - Review & Editing	YES
4065309	24950749	MTE	2	acquired data|contributed to the writing and/or revision|agreed with manuscript results and conclusions	agreed with manuscript results and conclusions	-	-	NO
4065309	24950749	OS	2	acquired data|contributed to the writing and/or revision|agreed with manuscript results and conclusions	acquired data	Performed the experiments	Investigation	YES
4065309	24950749	OS	2	acquired data|contributed to the writing and/or revision|agreed with manuscript results and conclusions	contributed to the writing and/or revision	Wrote the paper	Writing - Review & Editing	YES
4065309	24950749	OS	2	acquired data|contributed to the writing and/or revision|agreed with manuscript results and conclusions	agreed with manuscript results and conclusions	-	-	NO
4065309	24950749	RV	2	acquired data|contributed to the writing and/or revision|agreed with manuscript results and conclusions	acquired data	Performed the experiments	Investigation	YES
4065309	24950749	RV	2	acquired data|contributed to the writing and/or revision|agreed with manuscript results and conclusions	contributed to the writing and/or revision	Wrote the paper	Writing - Review & Editing	YES
4065309	24950749	RV	2	acquired data|contributed to the writing and/or revision|agreed with manuscript results and conclusions	agreed with manuscript results and conclusions	-	-	NO
4065309	24950749	S Sopheap	2	acquired data|contributed to the writing and/or revision|agreed with manuscript results and conclusions	acquired data	Performed the experiments	Investigation	YES
4065309	24950749	S Sopheap	2	acquired data|contributed to the writing and/or revision|agreed with manuscript results and conclusions	contributed to the writing and/or revision	Wrote the paper	Writing - Review & Editing	YES
4065309	24950749	S Sopheap	2	acquired data|contributed to the writing and/or revision|agreed with manuscript results and conclusions	agreed with manuscript results and conclusions	-	-	NO
4065309	24950749	S Sovannarith	2	acquired data|contributed to the writing and/or revision|agreed with manuscript results and conclusions	acquired data	Performed the experiments	Investigation	YES
4065309	24950749	S Sovannarith	2	acquired data|contributed to the writing and/or revision|agreed with manuscript results and conclusions	contributed to the writing and/or revision	Wrote the paper	Writing - Review & Editing	YES
4065309	24950749	S Sovannarith	2	acquired data|contributed to the writing and/or revision|agreed with manuscript results and conclusions	agreed with manuscript results and conclusions	-	-	NO
4065309	24950749	SB	2	acquired data|contributed to the writing and/or revision|agreed with manuscript results and conclusions	acquired data	Performed the experiments	Investigation	YES
4065309	24950749	SB	2	acquired data|contributed to the writing and/or revision|agreed with manuscript results and conclusions	contributed to the writing and/or revision	Wrote the paper	Writing - Review & Editing	YES
4065309	24950749	SB	2	acquired data|contributed to the writing and/or revision|agreed with manuscript results and conclusions	agreed with manuscript results and conclusions	-	-	NO
4065309	24950749	TR	2	acquired data|contributed to the writing and/or revision|agreed with manuscript results and conclusions	acquired data	Performed the experiments	Investigation	YES
4065309	24950749	TR	2	acquired data|contributed to the writing and/or revision|agreed with manuscript results and conclusions	contributed to the writing and/or revision	Wrote the paper	Writing - Review & Editing	YES
4065309	24950749	TR	2	acquired data|contributed to the writing and/or revision|agreed with manuscript results and conclusions	agreed with manuscript results and conclusions	-	-	NO
5097361	27814694	JF	2	designed the study, interpreted the data and wrote the manuscript|performed experimental work|did the bioinformatics analysis	designed the study, interpreted the data and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5097361	27814694	JF	2	designed the study, interpreted the data and wrote the manuscript|performed experimental work|did the bioinformatics analysis	performed experimental work	Performed the experiments	Investigation	YES
5097361	27814694	JF	2	designed the study, interpreted the data and wrote the manuscript|performed experimental work|did the bioinformatics analysis	did the bioinformatics analysis	-	Formal analysis	YES
5097361	27814694	LS	2	did the bioinformatics analysis	did the bioinformatics analysis	-	Formal analysis	YES
5097361	27814694	PY	2	designed the study, interpreted the data and wrote the manuscript	designed the study, interpreted the data and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5097361	27814694	TH	2	designed the study, interpreted the data and wrote the manuscript	designed the study, interpreted the data and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5097361	27814694	YM	2	provided the experimental materials and contributed to the experiments and discussion of results	provided the experimental materials and contributed to the experiments and discussion of results	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
3362018	22666132	D. Goncalves	2	participated equally to this paper	participated equally to this paper	-	-	NO
3362018	22666132	E. Xavier	2	participated equally to this paper	participated equally to this paper	-	-	NO
3362018	22666132	R. Prado	2	participated equally to this paper	participated equally to this paper	-	-	NO
5469197	28659951	HB	2	designed, planned and performed the experiments, analyzed the data and wrote the manuscript	designed, planned and performed the experiments, analyzed the data and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5469197	28659951	MH	2	supervised the project and wrote the manuscript	supervised the project and wrote the manuscript	Wrote the paper	Supervision|Writing - Original Draft	YES
4400174	25880375	BB	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400174	25880375	HC	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4400174	25880375	KK	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400174	25880375	KK	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4400174	25880375	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400174	25880375	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4400174	25880375	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4400174	25880375	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400174	25880375	SJ	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4400174	25880375	SR	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400174	25880375	SR	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4400174	25880375	WO	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4400174	25880375	WO	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4400174	25880375	WO	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2808049	20087439	AIP	7	Confocal expertise and image analysis	Confocal expertise and image analysis	Analyzed the data	Visualization	YES
2808049	20087439	GDK	7	Manuscript idea, critical revisions to manuscript	Manuscript idea, critical revisions to manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
2808049	20087439	IGP	7	Head of the department, revision of manuscript	Head of the department, revision of manuscript	Wrote the paper	Writing - Review & Editing	YES
2808049	20087439	MAG	7	Collection of clinical data, manuscript preparation	Collection of clinical data, manuscript preparation	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
2808049	20087439	VFD	7	Manuscript preparation, confocal microscopy image analysis	Manuscript preparation, confocal microscopy image analysis	Performed the experiments|Analyzed the data|Wrote the paper	Investigation|Visualization|Writing - Original Draft	YES
4069382	24962034	JF	2	extracted data|analysed and interpreted the results|edited subsequent versions and approved the final manuscript	extracted data	Performed the experiments	Investigation	YES
4069382	24962034	JF	2	extracted data|analysed and interpreted the results|edited subsequent versions and approved the final manuscript	analysed and interpreted the results	Analyzed the data	Formal analysis	YES
4069382	24962034	JF	2	extracted data|analysed and interpreted the results|edited subsequent versions and approved the final manuscript	edited subsequent versions and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4069382	24962034	MCB	2	analysed and interpreted the results|edited subsequent versions and approved the final manuscript	analysed and interpreted the results	Analyzed the data	Formal analysis	YES
4069382	24962034	MCB	2	analysed and interpreted the results|edited subsequent versions and approved the final manuscript	edited subsequent versions and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4069382	24962034	SM	2	extracted data|analysed and interpreted the results|edited subsequent versions and approved the final manuscript	extracted data	Performed the experiments	Investigation	YES
4069382	24962034	SM	2	extracted data|analysed and interpreted the results|edited subsequent versions and approved the final manuscript	analysed and interpreted the results	Analyzed the data	Formal analysis	YES
4069382	24962034	SM	2	extracted data|analysed and interpreted the results|edited subsequent versions and approved the final manuscript	edited subsequent versions and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4069382	24962034	ZS	2	extracted data|extracted data|analysed and interpreted the results|wrote the first manuscript|edited subsequent versions and approved the final manuscript	extracted data	Performed the experiments	Investigation	YES
4069382	24962034	ZS	2	extracted data|extracted data|analysed and interpreted the results|wrote the first manuscript|edited subsequent versions and approved the final manuscript	extracted data	Performed the experiments	Investigation	YES
4069382	24962034	ZS	2	extracted data|extracted data|analysed and interpreted the results|wrote the first manuscript|edited subsequent versions and approved the final manuscript	analysed and interpreted the results	Analyzed the data	Formal analysis	YES
4069382	24962034	ZS	2	extracted data|extracted data|analysed and interpreted the results|wrote the first manuscript|edited subsequent versions and approved the final manuscript	wrote the first manuscript	Wrote the paper	Writing - Original Draft	YES
4069382	24962034	ZS	2	extracted data|extracted data|analysed and interpreted the results|wrote the first manuscript|edited subsequent versions and approved the final manuscript	edited subsequent versions and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
2517064	18673571	AM	2	participated in study design and provided technical expertise|participated in study design and provided technical expertise	participated in study design and provided technical expertise	Conceived and designed the experiments	Methodology	YES
2517064	18673571	AM	2	participated in study design and provided technical expertise|participated in study design and provided technical expertise	participated in study design and provided technical expertise	Conceived and designed the experiments	Methodology	YES
2517064	18673571	AS	2	participated in the design, supervised study implementation and drafted the manuscript	participated in the design, supervised study implementation and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Supervision|Writing - Original Draft	YES
2517064	18673571	CM	2	participated in study implementation and data collection	participated in study implementation and data collection	Performed the experiments	Investigation	YES
2517064	18673571	EC	2	participated in study implementation and data collection	participated in study implementation and data collection	Performed the experiments	Investigation	YES
2517064	18673571	LS	2	participated in study implementation and data collection	participated in study implementation and data collection	Performed the experiments	Investigation	YES
2517064	18673571	MS	2	participated in study implementation and data collection	participated in study implementation and data collection	Performed the experiments	Investigation	YES
2517064	18673571	WC	2	participated in study implementation and data collection	participated in study implementation and data collection	Performed the experiments	Investigation	YES
2517064	18673571	YM	2	conceived the study, and participated in its design and coordination	conceived the study, and participated in its design and coordination	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
5469215	28659953	GQ	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5469215	28659953	JJ	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5469215	28659953	ML	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5469215	28659953	QH	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5469215	28659953	RZ	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5469215	28659953	XH	PLoS52	performed the experiments|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5469215	28659953	XH	PLoS52	performed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5469215	28659953	XS	PLoS52	performed the experiments|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5469215	28659953	XS	PLoS52	performed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5469215	28659953	YZ	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5469215	28659953	ZL	PLoS52	conceived and designed the experiments|performed the experiments|wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5469215	28659953	ZL	PLoS52	conceived and designed the experiments|performed the experiments|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5469215	28659953	ZL	PLoS52	conceived and designed the experiments|performed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4401436	25886207	CZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401436	25886207	CZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401436	25886207	CZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401436	25886207	CZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401436	25886207	FY	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401436	25886207	FY	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401436	25886207	JT	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401436	25886207	JT	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401436	25886207	SZ	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4436448	26075259	Huihui Yuan	PLoS52	conceived and designed the experiments|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4436448	26075259	Huihui Yuan	PLoS52	conceived and designed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4436448	26075259	Shentao Li	PLoS52	contributed reagents/materials/analysis tools	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4436448	26075259	Sibo Liu	PLoS52	performed the experiments|contributed equally to this work	performed the experiments	Performed the experiments	Investigation	YES
4436448	26075259	Sibo Liu	PLoS52	performed the experiments|contributed equally to this work	contributed equally to this work	-	-	NO
4436448	26075259	Wenming Zhao	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4436448	26075259	Xiaoqing Zhang	PLoS52	conceived and designed the experiments|performed the experiments|wrote the paper|contributed equally to this work	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4436448	26075259	Xiaoqing Zhang	PLoS52	conceived and designed the experiments|performed the experiments|wrote the paper|contributed equally to this work	performed the experiments	Performed the experiments	Investigation	YES
4436448	26075259	Xiaoqing Zhang	PLoS52	conceived and designed the experiments|performed the experiments|wrote the paper|contributed equally to this work	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4436448	26075259	Xiaoqing Zhang	PLoS52	conceived and designed the experiments|performed the experiments|wrote the paper|contributed equally to this work	contributed equally to this work	-	-	NO
4436448	26075259	Yunpeng Dou	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
4436448	26075259	Yuxuan Du	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
4436448	26075259	Zhanguo Li	PLoS52	contributed reagents/materials/analysis tools	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
3362020	22666095	M. T. Chou	3	The first two authors contributed equally to this work	The first two authors contributed equally to this work	-	-	NO
3362020	22666095	S. H. Lo	3	The first two authors contributed equally to this work	The first two authors contributed equally to this work	-	-	NO
2529329	18700986	EK	2	participated in the writing and editing of the manuscript	participated in the writing and editing of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
2529329	18700986	PC	2	participated in the research, writing, and editing of the manuscript	participated in the research, writing, and editing of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
2529329	18700986	RK	2	participated in the writing and editing of the manuscript	participated in the writing and editing of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
2529329	18700986	SC	2	participated in the writing and editing of the manuscript	participated in the writing and editing of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
2529329	18700986	SW	2	participated in the research, writing, and editing of the manuscript	participated in the research, writing, and editing of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
2529329	18700986	TF	2	participated in the writing and editing of the manuscript	participated in the writing and editing of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5097433	27814692	AAN	2	provided material, discussed the results and wrote the manuscript	provided material, discussed the results and wrote the manuscript	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Original Draft	YES
5097433	27814692	CS	2	provided the rna for library preparation|also made the ko mutants and analysed them	provided the rna for library preparation	Contributed reagents/materials/analysis tools	Resources	YES
5097433	27814692	CS	2	provided the rna for library preparation|also made the ko mutants and analysed them	also made the ko mutants and analysed them	Performed the experiments	Investigation	YES
5097433	27814692	GG	2	designed the study and wrote the manuscript	designed the study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5097433	27814692	HML	2	provided technical assistance throughout the work	provided technical assistance throughout the work	Performed the experiments	Investigation	YES
5097433	27814692	LE	2	provided material, discussed the results and wrote the manuscript	provided material, discussed the results and wrote the manuscript	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Original Draft	YES
5097433	27814692	PS	2	provided material, discussed the results and wrote the manuscript	provided material, discussed the results and wrote the manuscript	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Original Draft	YES
4401437	25885290	DS	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401437	25885290	DS	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401437	25885290	DS	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401437	25885290	FZ	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401437	25885290	JH	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401437	25885290	JH	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401437	25885290	PF	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401437	25885290	PF	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401437	25885290	PF	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401437	25885290	RE	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401437	25885290	RE	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401437	25885290	RE	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401437	25885290	UG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401437	25885290	UG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401437	25885290	UG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4074366	24973041	AC	2	provided scientific and content oversight	provided scientific and content oversight	-	Supervision	YES
4074366	24973041	All authors	2	made substantial contributions to the conception, data acquisition, analysis or interpretation of the data	made substantial contributions to the conception, data acquisition, analysis or interpretation of the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
4074366	24973041	BP	2	identified the research question	identified the research question	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
4074366	24973041	CO	2	provided thoughtful insights into data interpretation or a critical review of draft versions that have been incorporated into the final draft	provided thoughtful insights into data interpretation or a critical review of draft versions that have been incorporated into the final draft	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
4074366	24973041	CW	2	provided thoughtful insights into data interpretation or a critical review of draft versions that have been incorporated into the final draft	provided thoughtful insights into data interpretation or a critical review of draft versions that have been incorporated into the final draft	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
4074366	24973041	JO	2	provided thoughtful insights into data interpretation or a critical review of draft versions that have been incorporated into the final draft	provided thoughtful insights into data interpretation or a critical review of draft versions that have been incorporated into the final draft	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
4074366	24973041	KA	2	provided scientific and content oversight	provided scientific and content oversight	-	Supervision	YES
4074366	24973041	LOluoch	2	identified the research question	identified the research question	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
4074366	24973041	LOuma	2	provided thoughtful insights into data interpretation or a critical review of draft versions that have been incorporated into the final draft	provided thoughtful insights into data interpretation or a critical review of draft versions that have been incorporated into the final draft	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
2533343	18667075	RA	2	was responsible for the conception and overall implementation of the project	was responsible for the conception and overall implementation of the project	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5469908	28659966	AL-S	2	participated in the design of the study, carried out the experiments, collected and analyzed the data, and drafted the manuscript	participated in the design of the study, carried out the experiments, collected and analyzed the data, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5469908	28659966	JO	2	participated in the design of the study, discussion and interpretation of the results, and manuscript drafting	participated in the design of the study, discussion and interpretation of the results, and manuscript drafting	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5469908	28659966	OR	2	participated in the design of the study, discussion and interpretation of the results, and manuscript drafting	participated in the design of the study, discussion and interpretation of the results, and manuscript drafting	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5469908	28659966	SF	2	participated in the design of the study, discussion and interpretation of the results, and manuscript drafting	participated in the design of the study, discussion and interpretation of the results, and manuscript drafting	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5097439	27814695	All authors	PLoS52	reviewed and approved the final version of the manuscript	reviewed and approved the final version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5097439	27814695	LH	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5097439	27814695	MK	PLoS52	conceived and designed the experiments, performed data analysis and interpretation and wrote the manuscript|accept responsibility for the integrity of the data analysis	conceived and designed the experiments, performed data analysis and interpretation and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
5097439	27814695	MK	PLoS52	conceived and designed the experiments, performed data analysis and interpretation and wrote the manuscript|accept responsibility for the integrity of the data analysis	accept responsibility for the integrity of the data analysis	Analyzed the data	Data curation|Formal analysis	YES
5097439	27814695	MRW	PLoS52	conceived and designed the experiments, performed data analysis and interpretation and wrote the manuscript|accept responsibility for the integrity of the data analysis	conceived and designed the experiments, performed data analysis and interpretation and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
5097439	27814695	MRW	PLoS52	conceived and designed the experiments, performed data analysis and interpretation and wrote the manuscript|accept responsibility for the integrity of the data analysis	accept responsibility for the integrity of the data analysis	Analyzed the data	Data curation|Formal analysis	YES
5097439	27814695	NAT	PLoS52	conceived and designed the experiments, performed data analysis and interpretation and wrote the manuscript|accept responsibility for the integrity of the data analysis	conceived and designed the experiments, performed data analysis and interpretation and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
5097439	27814695	NAT	PLoS52	conceived and designed the experiments, performed data analysis and interpretation and wrote the manuscript|accept responsibility for the integrity of the data analysis	accept responsibility for the integrity of the data analysis	Analyzed the data	Data curation|Formal analysis	YES
4401438	25884830	AB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401438	25884830	ADM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401438	25884830	AH	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401438	25884830	AH	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401438	25884830	AL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401438	25884830	BS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401438	25884830	BS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401438	25884830	BS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401438	25884830	BS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401438	25884830	IRD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401438	25884830	IRD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401438	25884830	IRD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401438	25884830	JMK	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4401438	25884830	JMK	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401438	25884830	KK	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4401438	25884830	KK	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401438	25884830	MM	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401438	25884830	MM	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401438	25884830	NvR	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2543036	18759989	BC	2	contributed to design of the study and manuscript preparation	contributed to design of the study and manuscript preparation	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
2543036	18759989	CB	2	contributed to design of the study and manuscript preparation	contributed to design of the study and manuscript preparation	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
2543036	18759989	EB	2	conducted extensive medical record review and prepared preliminary analysis of the data	conducted extensive medical record review and prepared preliminary analysis of the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
2543036	18759989	EW	2	conducted extensive medical record review and prepared preliminary analysis of the data	conducted extensive medical record review and prepared preliminary analysis of the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
2543036	18759989	SM	2	advised on statistical analysis and contributed to the manuscript preparation	advised on statistical analysis and contributed to the manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
2543036	18759989	WCM	2	designed the study, conducted the final analysis, and prepared the manuscript	designed the study, conducted the final analysis, and prepared the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
4074603	24976436	ARZ	1	Analysis and interpretation of data|Critical revision of the manuscript for important intellectual content|Conceptual advice	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
4074603	24976436	ARZ	1	Analysis and interpretation of data|Critical revision of the manuscript for important intellectual content|Conceptual advice	Critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4074603	24976436	ARZ	1	Analysis and interpretation of data|Critical revision of the manuscript for important intellectual content|Conceptual advice	Conceptual advice	Conceived and designed the experiments	Conceptualization	YES
4074603	24976436	ETR	1	Study concept and design|Analysis and interpretation of data|Preparation of first manuscript	Study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4074603	24976436	ETR	1	Study concept and design|Analysis and interpretation of data|Preparation of first manuscript	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
4074603	24976436	ETR	1	Study concept and design|Analysis and interpretation of data|Preparation of first manuscript	Preparation of first manuscript	Wrote the paper	Writing - Original Draft	YES
4074603	24976436	JHJ	1	Analysis and interpretation of data|Critical revision of the manuscript for important intellectual content|Conceptual advice	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
4074603	24976436	JHJ	1	Analysis and interpretation of data|Critical revision of the manuscript for important intellectual content|Conceptual advice	Critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4074603	24976436	JHJ	1	Analysis and interpretation of data|Critical revision of the manuscript for important intellectual content|Conceptual advice	Conceptual advice	Conceived and designed the experiments	Conceptualization	YES
4074603	24976436	KHT	1	Analysis and interpretation of data|Critical revision of the manuscript for important intellectual content	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
4074603	24976436	KHT	1	Analysis and interpretation of data|Critical revision of the manuscript for important intellectual content	Critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4074603	24976436	LGB	1	Analysis and interpretation of data|Critical revision of the manuscript for important intellectual content|Conceptual advice	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
4074603	24976436	LGB	1	Analysis and interpretation of data|Critical revision of the manuscript for important intellectual content|Conceptual advice	Critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4074603	24976436	LGB	1	Analysis and interpretation of data|Critical revision of the manuscript for important intellectual content|Conceptual advice	Conceptual advice	Conceived and designed the experiments	Conceptualization	YES
4074603	24976436	SEC	1	Analysis and interpretation of data|Critical revision of the manuscript for important intellectual content	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
4074603	24976436	SEC	1	Analysis and interpretation of data|Critical revision of the manuscript for important intellectual content	Critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4074603	24976436	TK	1	Analysis and interpretation of data|Critical revision of the manuscript for important intellectual content	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
4074603	24976436	TK	1	Analysis and interpretation of data|Critical revision of the manuscript for important intellectual content	Critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4074603	24976436	VLB	1	Analysis and interpretation of data|Critical revision of the manuscript for important intellectual content	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
4074603	24976436	VLB	1	Analysis and interpretation of data|Critical revision of the manuscript for important intellectual content	Critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5469914	28659957	All authors	2	listed, have made substantial, direct and intellectual contribution to the work, and approved it for publication	listed, have made substantial, direct and intellectual contribution to the work, and approved it for publication	-	-	NO
2546423	18702834	EET	4	where written by	where written by	Wrote the paper	Writing - Original Draft	YES
2546423	18702834	GFD	4	where written by	where written by	Wrote the paper	Writing - Original Draft	YES
2546423	18702834	KD	4	where written by	where written by	Wrote the paper	Writing - Original Draft	YES
2546423	18702834	SM	4	where written by	where written by	Wrote the paper	Writing - Original Draft	YES
4401445	25886351	ATK	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401445	25886351	ATK	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401445	25886351	JS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401445	25886351	JS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401445	25886351	JWV	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401445	25886351	JWV	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401445	25886351	JWV	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401445	25886351	OPK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401445	25886351	OPK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401445	25886351	OPK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401445	25886351	RGJDOW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401445	25886351	RGJDOW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401445	25886351	RGJDOW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401445	25886351	RGJDOW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401445	25886351	SdJ	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4078101	24985779	AB	2	collected the data|contributed to the manuscripts review and edition	collected the data	Performed the experiments	Investigation	YES
4078101	24985779	AB	2	collected the data|contributed to the manuscripts review and edition	contributed to the manuscripts review and edition	Wrote the paper	Writing - Review & Editing	YES
4078101	24985779	ADL	2	designed the trial|contributed to the manuscripts review and edition	designed the trial	Conceived and designed the experiments	Methodology	YES
4078101	24985779	ADL	2	designed the trial|contributed to the manuscripts review and edition	contributed to the manuscripts review and edition	Wrote the paper	Writing - Review & Editing	YES
4078101	24985779	CD	2	designed the trial|collected the data|contributed to the manuscripts review and edition	designed the trial	Conceived and designed the experiments	Methodology	YES
4078101	24985779	CD	2	designed the trial|collected the data|contributed to the manuscripts review and edition	collected the data	Performed the experiments	Investigation	YES
4078101	24985779	CD	2	designed the trial|collected the data|contributed to the manuscripts review and edition	contributed to the manuscripts review and edition	Wrote the paper	Writing - Review & Editing	YES
4078101	24985779	DG	2	conceived and designed the analysis|contributed to the manuscripts review and edition	conceived and designed the analysis	Conceived and designed the experiments	Conceptualization	YES
4078101	24985779	DG	2	conceived and designed the analysis|contributed to the manuscripts review and edition	contributed to the manuscripts review and edition	Wrote the paper	Writing - Review & Editing	YES
4078101	24985779	FL	2	conceived and designed the analysis|wrote the first draft of the manuscript	conceived and designed the analysis	Conceived and designed the experiments	Conceptualization	YES
4078101	24985779	FL	2	conceived and designed the analysis|wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
4078101	24985779	JBN	2	collected the data|contributed to the manuscripts review and edition	collected the data	Performed the experiments	Investigation	YES
4078101	24985779	JBN	2	collected the data|contributed to the manuscripts review and edition	contributed to the manuscripts review and edition	Wrote the paper	Writing - Review & Editing	YES
4078101	24985779	JLC	2	collected the data|contributed to the manuscripts review and edition	collected the data	Performed the experiments	Investigation	YES
4078101	24985779	JLC	2	collected the data|contributed to the manuscripts review and edition	contributed to the manuscripts review and edition	Wrote the paper	Writing - Review & Editing	YES
4078101	24985779	KJ	2	conceived and designed the analysis|conducted the analysis|wrote the first draft of the manuscript	conceived and designed the analysis	Conceived and designed the experiments	Conceptualization	YES
4078101	24985779	KJ	2	conceived and designed the analysis|conducted the analysis|wrote the first draft of the manuscript	conducted the analysis	Performed the experiments	Investigation	YES
4078101	24985779	KJ	2	conceived and designed the analysis|conducted the analysis|wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
4078101	24985779	RDS	2	conceived and designed the analysis|wrote the first draft of the manuscript	conceived and designed the analysis	Conceived and designed the experiments	Conceptualization	YES
4078101	24985779	RDS	2	conceived and designed the analysis|wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
4078101	24985779	RM	2	designed the trial|collected the data|contributed to the manuscripts review and edition	designed the trial	Conceived and designed the experiments	Methodology	YES
4078101	24985779	RM	2	designed the trial|collected the data|contributed to the manuscripts review and edition	collected the data	Performed the experiments	Investigation	YES
4078101	24985779	RM	2	designed the trial|collected the data|contributed to the manuscripts review and edition	contributed to the manuscripts review and edition	Wrote the paper	Writing - Review & Editing	YES
4078101	24985779	SE	2	designed the trial|contributed to the manuscripts review and edition	designed the trial	Conceived and designed the experiments	Methodology	YES
4078101	24985779	SE	2	designed the trial|contributed to the manuscripts review and edition	contributed to the manuscripts review and edition	Wrote the paper	Writing - Review & Editing	YES
4078101	24985779	XA	2	designed the trial|collected the data|contributed to the manuscripts review and edition	designed the trial	Conceived and designed the experiments	Methodology	YES
4078101	24985779	XA	2	designed the trial|collected the data|contributed to the manuscripts review and edition	collected the data	Performed the experiments	Investigation	YES
4078101	24985779	XA	2	designed the trial|collected the data|contributed to the manuscripts review and edition	contributed to the manuscripts review and edition	Wrote the paper	Writing - Review & Editing	YES
5097440	27814671	AJL	2	provided the hmdp gwas and twas data|provided the hmdp ewas data	provided the hmdp gwas and twas data	Contributed reagents/materials/analysis tools	Resources	YES
5097440	27814671	AJL	2	provided the hmdp gwas and twas data|provided the hmdp ewas data	provided the hmdp ewas data	Contributed reagents/materials/analysis tools	Resources	YES
5097440	27814671	BZ	2	provided support for kda	provided support for kda	-	-	NO
5097440	27814671	JK	2	provided cholesterol genetic data and conducted genetic association analysis	provided cholesterol genetic data and conducted genetic association analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5097440	27814671	LDO	2	provided the hmdp ewas data	provided the hmdp ewas data	Contributed reagents/materials/analysis tools	Resources	YES
5097440	27814671	LS	2	modified the mergeomics pipeline and performed the statistical analyses, method comparisons and case studies|wrote the manuscript	modified the mergeomics pipeline and performed the statistical analyses, method comparisons and case studies	Performed the experiments|Analyzed the data	Formal analysis	YES
5097440	27814671	LS	2	modified the mergeomics pipeline and performed the statistical analyses, method comparisons and case studies|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5097440	27814671	MI	2	provided cholesterol genetic data and conducted genetic association analysis	provided cholesterol genetic data and conducted genetic association analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5097440	27814671	MP	2	provided the hmdp ewas data	provided the hmdp ewas data	Contributed reagents/materials/analysis tools	Resources	YES
5097440	27814671	SB	2	provided cholesterol genetic data and conducted genetic association analysis	provided cholesterol genetic data and conducted genetic association analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5097440	27814671	SR	2	provided cholesterol genetic data and conducted genetic association analysis	provided cholesterol genetic data and conducted genetic association analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5097440	27814671	TT	2	provided cholesterol genetic data and conducted genetic association analysis	provided cholesterol genetic data and conducted genetic association analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5097440	27814671	VPM	2	conceived the study|implemented the mergeomics algorithms|wrote the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5097440	27814671	VPM	2	conceived the study|implemented the mergeomics algorithms|wrote the manuscript	implemented the mergeomics algorithms	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5097440	27814671	VPM	2	conceived the study|implemented the mergeomics algorithms|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5097440	27814671	XY	2	conceived the study|wrote the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5097440	27814671	XY	2	conceived the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5097440	27814671	YZ	2	assisted in building the mergeomics r package and accessing hmdp data	assisted in building the mergeomics r package and accessing hmdp data	-	Software	YES
5097440	27814671	ZK	2	assisted in building the mergeomics r package and accessing hmdp data	assisted in building the mergeomics r package and accessing hmdp data	-	Software	YES
5097440	27814671	all authors	2	reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
4106691	24911113	SS	2	have equally contributed to this manuscript	have equally contributed to this manuscript	-	-	NO
4106691	24911113	The authors	2	have equally contributed to this manuscript	have equally contributed to this manuscript	-	-	NO
4436451	26075221	Maria Galuppo	2	contributed equally to this work	contributed equally to this work	-	-	NO
4436451	26075221	Sabrina Giacoppo	2	contributed equally to this work	contributed equally to this work	-	-	NO
3362024	22666099	G. Cancrini	2	conceived the study, participated in its design, and helped to draft the paper	conceived the study, participated in its design, and helped to draft the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
3362024	22666099	P. Calderini	2	gave substantial contribution to conception, design and coordination of the study and carried out parasitological analyses	gave substantial contribution to conception, design and coordination of the study and carried out parasitological analyses	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation|Methodology|Project administration	YES
3362024	22666099	S. Gabrielli	2	carried out the morphological analysis of the hooks collected and the molecular genetic studies and participated in the interpretation of the results	carried out the morphological analysis of the hooks collected and the molecular genetic studies and participated in the interpretation of the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4401446	25884638	ACV	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401446	25884638	ATA	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401446	25884638	ATL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401446	25884638	ATL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401446	25884638	ATL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401446	25884638	GLV	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401446	25884638	GLV	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401446	25884638	HRV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401446	25884638	HRV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401446	25884638	HRV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401446	25884638	HRV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401446	25884638	IGT	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401446	25884638	IMM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401446	25884638	IMM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4401446	25884638	IMM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401446	25884638	JMQ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401446	25884638	JOH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401446	25884638	JOH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401446	25884638	JOH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401446	25884638	JOH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401446	25884638	SEF	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4401446	25884638	SEF	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401446	25884638	SGM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401446	25884638	STM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5470051	28659962	AG	1	Plant material, experiment design, discussion writing, and manuscripts review	Plant material, experiment design, discussion writing, and manuscripts review	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5470051	28659962	CX	1	Plant material, experiment design, discussion writing, and manuscripts review	Plant material, experiment design, discussion writing, and manuscripts review	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5470051	28659962	GL	1	Chromosomal location and express level experiment	Chromosomal location and express level experiment	-	-	NO
5470051	28659962	HX	1	Plant material, experiment design, discussion writing, and manuscripts review	Plant material, experiment design, discussion writing, and manuscripts review	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5470051	28659962	XG	1	Chromosomal location and express level experiment	Chromosomal location and express level experiment	-	-	NO
5470051	28659962	XP	1	Plant material, experiment design, discussion writing, and manuscripts review	Plant material, experiment design, discussion writing, and manuscripts review	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5470051	28659962	XZ	1	Plant material, experiment design, discussion writing, and manuscripts review	Plant material, experiment design, discussion writing, and manuscripts review	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5470051	28659962	YT	1	Cultivating the wheat plants, sample collection, and mrna extraction	Cultivating the wheat plants, sample collection, and mrna extraction	Performed the experiments	Investigation	YES
5470051	28659962	YY	1	Cultivating the wheat plants, sample collection, and mrna extraction	Cultivating the wheat plants, sample collection, and mrna extraction	Performed the experiments	Investigation	YES
4082255	24993457	All authors	2	interpreted the data, revised the article and approved the final version	interpreted the data, revised the article and approved the final version	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4082255	24993457	JX	2	contributed to part of the analysis|drafted the paper	contributed to part of the analysis	-	-	NO
4082255	24993457	JX	2	contributed to part of the analysis|drafted the paper	drafted the paper	Wrote the paper	Writing - Original Draft	YES
4082255	24993457	WD	2	drafted the paper	drafted the paper	Wrote the paper	Writing - Original Draft	YES
4082255	24993457	XB	2	drafted the paper	drafted the paper	Wrote the paper	Writing - Original Draft	YES
5097849	27816055	JL	2	design and carried out the molecular genetic studies, bio-information analyses, data analyses and manuscript drafting	design and carried out the molecular genetic studies, bio-information analyses, data analyses and manuscript drafting	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5097849	27816055	JX	2	developed chicken dendritic cells and performed qrt-pcr analyses	developed chicken dendritic cells and performed qrt-pcr analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5097849	27816055	KZ	2	anticipated in the interpretations of the data and participated in its design and coordination experiment in the lab	anticipated in the interpretations of the data and participated in its design and coordination experiment in the lab	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology|Project administration	YES
5097849	27816055	QY	2	is the principal investigator of the project, who conceived the study, participated in its design and helped to draft the manuscript	is the principal investigator of the project, who conceived the study, participated in its design and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Funding acquisition|Methodology|Writing - Original Draft	YES
2563011	18799008	KGE	2	participated in the conception and design of the study, and the analysis and interpretation of the data	participated in the conception and design of the study, and the analysis and interpretation of the data	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
2563011	18799008	LWR	2	participated in the conception and design of the study, and the analysis and interpretation of the data	participated in the conception and design of the study, and the analysis and interpretation of the data	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
2563011	18799008	PP	2	participated in the conception and design of the study	participated in the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
2563011	18799008	SKC	2	participated in the conception and design of the study, analysis and interpretation of the data, and development of the manuscript	participated in the conception and design of the study, analysis and interpretation of the data, and development of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
2563011	18799008	SS	2	participated in the analysis and interpretation of the data and the development of the manuscript	participated in the analysis and interpretation of the data and the development of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4401450	25886557	JQZ	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401450	25886557	JZ	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401450	25886557	LL	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401450	25886557	LL	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401450	25886557	MY	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401450	25886557	XXZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401450	25886557	XXZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401450	25886557	XXZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401450	25886557	XXZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401450	25886557	XXZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401450	25886557	XZ	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
3979130	24617924	All authors	2	have given approval to the final version of the manuscript	have given approval to the final version of the manuscript	-	-	NO
3614780	23675152	DC	2	analyzed the data and wrote the paper	analyzed the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3614780	23675152	NL	2	analyzed the data and wrote the paper	analyzed the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3614780	23675152	YS	2	analyzed the data and wrote the paper	analyzed the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5470080	28659961	AL	PLoS52	analyze the rna seq data	analyze the rna seq data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5470080	28659961	BZ	PLoS52	analyzed the phenotype data	analyzed the phenotype data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5470080	28659961	HD	PLoS52	designed the study|wrote the paper	designed the study	Conceived and designed the experiments	Methodology	YES
5470080	28659961	HD	PLoS52	designed the study|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5470080	28659961	HS	PLoS52	performed maize waterlogging treatment and analyzed growth traits	performed maize waterlogging treatment and analyzed growth traits	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5470080	28659961	HW	PLoS52	analyze the rna seq data	analyze the rna seq data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5470080	28659961	JZ	PLoS52	performed maize waterlogging treatment and analyzed growth traits|isolated total rna from roots of maize, and performed qrt pcr	performed maize waterlogging treatment and analyzed growth traits	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5470080	28659961	JZ	PLoS52	performed maize waterlogging treatment and analyzed growth traits|isolated total rna from roots of maize, and performed qrt pcr	isolated total rna from roots of maize, and performed qrt pcr	Performed the experiments	Investigation	YES
5470080	28659961	MH	PLoS52	analyzed the phenotype data	analyzed the phenotype data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5470080	28659961	SD	PLoS52	analyze the rna seq data	analyze the rna seq data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5470080	28659961	SW	PLoS52	analyzed the phenotype data	analyzed the phenotype data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5470080	28659961	XT	PLoS52	analyzed the phenotype data	analyzed the phenotype data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5470080	28659961	YX	PLoS52	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
4083185	24998532	BM	1	Critical revision for content	Critical revision for content	Wrote the paper	Writing - Review & Editing	YES
4083185	24998532	JMC	1	Conception, data search, data abstraction|Data analyses and write up|Critical revision for content	Conception, data search, data abstraction	Conceived and designed the experiments	Conceptualization	YES
4083185	24998532	JMC	1	Conception, data search, data abstraction|Data analyses and write up|Critical revision for content	Data analyses and write up	Analyzed the data|Wrote the paper	Formal analysis	YES
4083185	24998532	JMC	1	Conception, data search, data abstraction|Data analyses and write up|Critical revision for content	Critical revision for content	Wrote the paper	Writing - Review & Editing	YES
4083185	24998532	MB	1	Conception, data search, data abstraction|Data analyses and write up	Conception, data search, data abstraction	Conceived and designed the experiments	Conceptualization	YES
4083185	24998532	MB	1	Conception, data search, data abstraction|Data analyses and write up	Data analyses and write up	Analyzed the data|Wrote the paper	Formal analysis	YES
4083185	24998532	MK	1	Conception, data search, data abstraction|Data analyses and write up|Critical revision for content	Conception, data search, data abstraction	Conceived and designed the experiments	Conceptualization	YES
4083185	24998532	MK	1	Conception, data search, data abstraction|Data analyses and write up|Critical revision for content	Data analyses and write up	Analyzed the data|Wrote the paper	Formal analysis	YES
4083185	24998532	MK	1	Conception, data search, data abstraction|Data analyses and write up|Critical revision for content	Critical revision for content	Wrote the paper	Writing - Review & Editing	YES
4083185	24998532	MW	1	Conception, data search, data abstraction|Data analyses and write up|Critical revision for content	Conception, data search, data abstraction	Conceived and designed the experiments	Conceptualization	YES
4083185	24998532	MW	1	Conception, data search, data abstraction|Data analyses and write up|Critical revision for content	Data analyses and write up	Analyzed the data|Wrote the paper	Formal analysis	YES
4083185	24998532	MW	1	Conception, data search, data abstraction|Data analyses and write up|Critical revision for content	Critical revision for content	Wrote the paper	Writing - Review & Editing	YES
4083185	24998532	NPP	1	Conception, data search, data abstraction|Data analyses and write up|Critical revision for content	Conception, data search, data abstraction	Conceived and designed the experiments	Conceptualization	YES
4083185	24998532	NPP	1	Conception, data search, data abstraction|Data analyses and write up|Critical revision for content	Data analyses and write up	Analyzed the data|Wrote the paper	Formal analysis	YES
4083185	24998532	NPP	1	Conception, data search, data abstraction|Data analyses and write up|Critical revision for content	Critical revision for content	Wrote the paper	Writing - Review & Editing	YES
5098276	27821074	HH	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5098276	27821074	KZ	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5098276	27821074	LB	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5098276	27821074	UB	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5098276	27821074	WB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5098276	27821074	XJ	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5098276	27821074	XZ	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
5098276	27821074	XZ	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5098276	27821074	YF	PLoS5	Performed the experiments|Analyzed the data|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
5098276	27821074	YF	PLoS5	Performed the experiments|Analyzed the data|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5098276	27821074	YF	PLoS5	Performed the experiments|Analyzed the data|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5098276	27821074	YF	PLoS5	Performed the experiments|Analyzed the data|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5098276	27821074	YW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5098276	27821074	ZW	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401451	25885435	APR	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401451	25885435	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401451	25885435	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4401451	25885435	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401451	25885435	MR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401451	25885435	MR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401451	25885435	MR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401451	25885435	MR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401451	25885435	NB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401451	25885435	NB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4401451	25885435	NB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401451	25885435	PMIAD	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4401451	25885435	PMIAD	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2569082	18837993	AC	PLoS52	conceived the study|analyzed data|wrote the paper	conceived the study	Conceived and designed the experiments	Conceptualization	YES
2569082	18837993	AC	PLoS52	conceived the study|analyzed data|wrote the paper	analyzed data	Analyzed the data	Formal analysis	YES
2569082	18837993	AC	PLoS52	conceived the study|analyzed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
2569082	18837993	All authors	PLoS52	provided editorial comments and assistance	provided editorial comments and assistance	-	-	NO
2569082	18837993	BS	PLoS52	performed experiments|analyzed data	performed experiments	Performed the experiments	Investigation	YES
2569082	18837993	BS	PLoS52	performed experiments|analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
2569082	18837993	CJD	PLoS52	performed experiments|analyzed data	performed experiments	Performed the experiments	Investigation	YES
2569082	18837993	CJD	PLoS52	performed experiments|analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
2569082	18837993	FDG	PLoS52	participated to the collection of patient samples	participated to the collection of patient samples	Performed the experiments	Investigation	YES
2569082	18837993	GP	PLoS52	participated to the collection of patient samples	participated to the collection of patient samples	Performed the experiments	Investigation	YES
2569082	18837993	GT	PLoS52	participated to the collection of patient samples	participated to the collection of patient samples	Performed the experiments	Investigation	YES
2569082	18837993	HJS	PLoS52	participated to the collection of patient samples	participated to the collection of patient samples	Performed the experiments	Investigation	YES
2569082	18837993	HP	PLoS52	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
2569082	18837993	JRB	PLoS52	participated to the collection of patient samples	participated to the collection of patient samples	Performed the experiments	Investigation	YES
2569082	18837993	MM	PLoS52	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
2569082	18837993	MT	PLoS52	participated to the collection of patient samples	participated to the collection of patient samples	Performed the experiments	Investigation	YES
2569082	18837993	PB	PLoS52	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
2569082	18837993	PL	PLoS52	contributed to research and critical discussion	contributed to research and critical discussion	-	-	NO
2569082	18837993	SA	PLoS52	performed experiments|analyzed data	performed experiments	Performed the experiments	Investigation	YES
2569082	18837993	SA	PLoS52	performed experiments|analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
2569082	18837993	SH	PLoS52	performed experiments|analyzed data	performed experiments	Performed the experiments	Investigation	YES
2569082	18837993	SH	PLoS52	performed experiments|analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
2569082	18837993	SK	PLoS52	conceived the study|performed experiments|analyzed data|wrote the paper	conceived the study	Conceived and designed the experiments	Conceptualization	YES
2569082	18837993	SK	PLoS52	conceived the study|performed experiments|analyzed data|wrote the paper	performed experiments	Performed the experiments	Investigation	YES
2569082	18837993	SK	PLoS52	conceived the study|performed experiments|analyzed data|wrote the paper	analyzed data	Analyzed the data	Formal analysis	YES
2569082	18837993	SK	PLoS52	conceived the study|performed experiments|analyzed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
2569082	18837993	SN	PLoS52	participated to the collection of patient samples	participated to the collection of patient samples	Performed the experiments	Investigation	YES
2569082	18837993	VE	PLoS52	contributed to research and critical discussion	contributed to research and critical discussion	-	-	NO
4087168	25005046	AK	2	provided field support supervision	provided field support supervision	-	Supervision	YES
4087168	25005046	All authors	2	participated in the conception and design of the study|reviewed, revised and approved the final manuscript	participated in the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4087168	25005046	All authors	2	participated in the conception and design of the study|reviewed, revised and approved the final manuscript	reviewed, revised and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4087168	25005046	DK	2	provided field support supervision	provided field support supervision	-	Supervision	YES
4087168	25005046	PK	2	took the lead role during the analysis|during the analysis and writing of the manuscript	took the lead role during the analysis	-	-	NO
4087168	25005046	PK	2	took the lead role during the analysis|during the analysis and writing of the manuscript	during the analysis and writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
4087168	25005046	SM	2	took the lead role during the analysis	took the lead role during the analysis	-	-	NO
4087168	25005046	SW	2	provided field support supervision	provided field support supervision	-	Supervision	YES
3362026	22666143	J. Zhou	2	contributed equally to this research	contributed equally to this research	-	-	NO
3362026	22666143	Y. Zhao	2	contributed equally to this research	contributed equally to this research	-	-	NO
5470089	28659964	PV	PLoS52	designed the experiments|analyzed data|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5470089	28659964	PV	PLoS52	designed the experiments|analyzed data|wrote the manuscript	analyzed data	Analyzed the data	Formal analysis	YES
5470089	28659964	PV	PLoS52	designed the experiments|analyzed data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5470089	28659964	RG	PLoS52	designed the experiments|performed bioinformatics analysis|analyzed data|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5470089	28659964	RG	PLoS52	designed the experiments|performed bioinformatics analysis|analyzed data|wrote the manuscript	performed bioinformatics analysis	Performed the experiments	Formal analysis|Investigation	YES
5470089	28659964	RG	PLoS52	designed the experiments|performed bioinformatics analysis|analyzed data|wrote the manuscript	analyzed data	Analyzed the data	Formal analysis	YES
5470089	28659964	RG	PLoS52	designed the experiments|performed bioinformatics analysis|analyzed data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5470089	28659964	SV	PLoS52	designed the experiments|performed bioinformatics analysis|performed the experiments|analyzed data|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5470089	28659964	SV	PLoS52	designed the experiments|performed bioinformatics analysis|performed the experiments|analyzed data|wrote the manuscript	performed bioinformatics analysis	Performed the experiments	Formal analysis|Investigation	YES
5470089	28659964	SV	PLoS52	designed the experiments|performed bioinformatics analysis|performed the experiments|analyzed data|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5470089	28659964	SV	PLoS52	designed the experiments|performed bioinformatics analysis|performed the experiments|analyzed data|wrote the manuscript	analyzed data	Analyzed the data	Formal analysis	YES
5470089	28659964	SV	PLoS52	designed the experiments|performed bioinformatics analysis|performed the experiments|analyzed data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4401452	25885582	DY	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401452	25885582	GH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401452	25885582	GL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401452	25885582	HY	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401452	25885582	JZ	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401452	25885582	JZ	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401452	25885582	QZ	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401452	25885582	XZ	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401452	25885582	YC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401452	25885582	YX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401452	25885582	YX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401452	25885582	YX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401452	25885582	YX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401452	25885582	YX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5100079	27821072	AG	2	designed and performed qrt pcr assays and contributed to qrt-pcr data analysis	designed and performed qrt pcr assays and contributed to qrt-pcr data analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5100079	27821072	AK	2	devised the study and contributed to experimental design and data interpretation	devised the study and contributed to experimental design and data interpretation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Methodology|Resources	YES
5100079	27821072	PB	2	performed rna extractions, analysed data, prepared figures and wrote the manuscript	performed rna extractions, analysed data, prepared figures and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Visualization|Writing - Original Draft	YES
4093768	25014321	All authors	2	contributed to the design of the study|provided feedback on drafts and approved its final version	contributed to the design of the study	Conceived and designed the experiments	Methodology	YES
4093768	25014321	All authors	2	contributed to the design of the study|provided feedback on drafts and approved its final version	provided feedback on drafts and approved its final version	Wrote the paper	Writing - Original Draft	YES
4093768	25014321	EB	2	oversaw data collection and management	oversaw data collection and management	Performed the experiments	Investigation|Supervision	YES
4093768	25014321	EK	2	oversaw data collection and management	oversaw data collection and management	Performed the experiments	Investigation|Supervision	YES
4093768	25014321	EQ	2	conducted the analysis	conducted the analysis	Performed the experiments	Investigation	YES
4093768	25014321	KL	2	drafted the article	drafted the article	Wrote the paper	Writing - Original Draft	YES
2584102	18957095	CE	2	were responsible for patients inclusion and follow up, and acquiring the data	were responsible for patients inclusion and follow up, and acquiring the data	Performed the experiments	Investigation	YES
2584102	18957095	CP	2	were responsible for patients inclusion and follow up, and acquiring the data	were responsible for patients inclusion and follow up, and acquiring the data	Performed the experiments	Investigation	YES
2584102	18957095	DAC	2	helped ja design and write the protocol, and provided oversight and advice through out the study	helped ja design and write the protocol, and provided oversight and advice through out the study	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision	YES
2584102	18957095	JA	2	designed the study, wrote the protocol, organized and coordinated the study, acquired the data and wrote the manuscript	designed the study, wrote the protocol, organized and coordinated the study, acquired the data and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Project administration|Writing - Original Draft	YES
2584102	18957095	JI	2	helped ja coordinate the study, acquire and monitor data at all sites	helped ja coordinate the study, acquire and monitor data at all sites	Performed the experiments	Investigation|Project administration|Supervision	YES
2584102	18957095	JL	2	helped ja design and write the protocol, and provided oversight and advice through out the study	helped ja design and write the protocol, and provided oversight and advice through out the study	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision	YES
2584102	18957095	PK	2	coordinated the study at one site, acquired the data and helped write the manuscript	coordinated the study at one site, acquired the data and helped write the manuscript	Performed the experiments|Wrote the paper	Investigation|Project administration|Writing - Original Draft	YES
2584102	18957095	PL	2	were responsible for patients inclusion and follow up, and acquiring the data	were responsible for patients inclusion and follow up, and acquiring the data	Performed the experiments	Investigation	YES
2584102	18957095	PP	2	helped ja design and write the protocol, and provided oversight and advice through out the study	helped ja design and write the protocol, and provided oversight and advice through out the study	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision	YES
2584102	18957095	SU	2	coordinated and defined strategies for analyzing all samples	coordinated and defined strategies for analyzing all samples	Analyzed the data	Formal analysis|Project administration	YES
2584102	18957095	TB	2	assisted ja in following patients, acquiring data and writing manuscript	assisted ja in following patients, acquiring data and writing manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
2584102	18957095	TC	2	helped ja coordinate the study, acquire and monitor data at all sites	helped ja coordinate the study, acquire and monitor data at all sites	Performed the experiments	Investigation|Project administration|Supervision	YES
2584102	18957095	US	2	analyzed the data and helped write the manuscript	analyzed the data and helped write the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
2584102	18957095	WA	2	helped ja coordinate the study, acquire and monitor data at all sites	helped ja coordinate the study, acquire and monitor data at all sites	Performed the experiments	Investigation|Project administration|Supervision	YES
5470093	28659965	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5470093	28659965	DG	2	conceived the study, participated in its design and assisted to draft the manuscript	conceived the study, participated in its design and assisted to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
5470093	28659965	PS	2	conceived the study, participated in its design and assisted to draft the manuscript	conceived the study, participated in its design and assisted to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
5470093	28659965	RD	2	conducted bioassays, wrote the manuscript and analyzed the data	conducted bioassays, wrote the manuscript and analyzed the data	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5470093	28659965	RF	2	conceived the study, participated in its design and assisted to draft the manuscript	conceived the study, participated in its design and assisted to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
5399648	28270564	C.D.A.	1	Contributed new reagents or analytic tools	Contributed new reagents or analytic tools	Contributed reagents/materials/analysis tools	Resources	YES
5399648	28270564	J. Brown	1	Contributed new reagents or analytic tools	Contributed new reagents or analytic tools	Contributed reagents/materials/analysis tools	Resources	YES
4401453	25884837	BH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401453	25884837	CQ	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4401453	25884837	CQ	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401453	25884837	DL	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4401453	25884837	DL	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401453	25884837	GH	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401453	25884837	GT	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401453	25884837	HY	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401453	25884837	HY	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401453	25884837	JC	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4401453	25884837	JC	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401453	25884837	JZ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401453	25884837	LZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401453	25884837	PL	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4401453	25884837	PL	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401453	25884837	SB	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401453	25884837	XZ	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4401453	25884837	XZ	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401453	25884837	YB	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4401453	25884837	YB	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401453	25884837	YZ	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4401453	25884837	YZ	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4437250	26075274	Manli Zhou	2	contributed equally to this work	contributed equally to this work	-	-	NO
4437250	26075274	Youxi Luo	2	contributed equally to this work	contributed equally to this work	-	-	NO
5470102	28659950	BW	2	planned and designed experiments|wrote the manuscript	planned and designed experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5470102	28659950	BW	2	planned and designed experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5470102	28659950	RR	2	planned and designed experiments|conducted experiments and performed statistical and bioinformatics analysis|wrote the manuscript	planned and designed experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5470102	28659950	RR	2	planned and designed experiments|conducted experiments and performed statistical and bioinformatics analysis|wrote the manuscript	conducted experiments and performed statistical and bioinformatics analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5470102	28659950	RR	2	planned and designed experiments|conducted experiments and performed statistical and bioinformatics analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4104297	25043381	MAW	2	all contributed to the preparation of the manuscript	all contributed to the preparation of the manuscript	Wrote the paper	Writing - Original Draft	YES
4104297	25043381	MB	2	all contributed to the preparation of the manuscript	all contributed to the preparation of the manuscript	Wrote the paper	Writing - Original Draft	YES
4104297	25043381	PSS	2	all contributed to the preparation of the manuscript	all contributed to the preparation of the manuscript	Wrote the paper	Writing - Original Draft	YES
4104297	25043381	SK	2	all contributed to the preparation of the manuscript	all contributed to the preparation of the manuscript	Wrote the paper	Writing - Original Draft	YES
5100175	27821048	All authors	2	reviewed and edited the manuscript before submission	reviewed and edited the manuscript before submission	Wrote the paper	Writing - Review & Editing	YES
5100175	27821048	BZhang	2	designed the research projects	designed the research projects	Conceived and designed the experiments	Methodology	YES
5100175	27821048	BZhao	2	designed the research projects|wrote the manuscript	designed the research projects	Conceived and designed the experiments	Methodology	YES
5100175	27821048	BZhao	2	designed the research projects|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5100175	27821048	DNA	2	did rna seq analysis and snp validation	did rna seq analysis and snp validation	Performed the experiments	Investigation|Validation	YES
5100175	27821048	GS	2	designed the research projects|wrote the manuscript	designed the research projects	Conceived and designed the experiments	Methodology	YES
5100175	27821048	GS	2	designed the research projects|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5100175	27821048	JJ	2	carried out sequencing, assembly, and annotation of the switchgrass genome	carried out sequencing, assembly, and annotation of the switchgrass genome	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5100175	27821048	JS	2	carried out sequencing, assembly, and annotation of the switchgrass genome	carried out sequencing, assembly, and annotation of the switchgrass genome	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5100175	27821048	NAP	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5100175	27821048	SS	2	carried out sequencing, assembly, and annotation of the switchgrass genome	carried out sequencing, assembly, and annotation of the switchgrass genome	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5100175	27821048	TPF	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3993889	24528178	P These	2	workers contributed equally to this work	workers contributed equally to this work	-	-	NO
2605744	18957083	AK	2	participated in the study design and statistical analysis	participated in the study design and statistical analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
2605744	18957083	BC	2	participated in the acquisition of data, coordination of the study and in revising the paper	participated in the acquisition of data, coordination of the study and in revising the paper	Performed the experiments|Wrote the paper	Investigation|Project administration|Writing - Review & Editing	YES
2605744	18957083	DN	2	conceived of the study, and participated in the design, data analysis, interpretation of data, drafting and revising the paper	conceived of the study, and participated in the design, data analysis, interpretation of data, drafting and revising the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
2605744	18957083	FI	2	participated in the statistical analysis	participated in the statistical analysis	Analyzed the data	Formal analysis	YES
2605744	18957083	MRK	2	made substantial contribution to the conception, design and coordination of the study	made substantial contribution to the conception, design and coordination of the study	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
2605744	18957083	PJE	2	made substantial contribution study design, statistical analysis and revision of the paper	made substantial contribution study design, statistical analysis and revision of the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
2615784	19102769	DD	2	wrote the proposal, secured the funding and organized the data collection	wrote the proposal, secured the funding and organized the data collection	Performed the experiments|Wrote the paper	Funding acquisition|Investigation|Writing - Original Draft	YES
2615784	19102769	EL	2	analysed and interpreted the data and developed the manuscript	analysed and interpreted the data and developed the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4438141	26064956	Jian Wang	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
4438141	26064956	Yong Du	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
4104298	25043380	B. The	2	other authors contributed to the overall manuscript edits and ideas	other authors contributed to the overall manuscript edits and ideas	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
4104298	25043380	CB	2	directed the writing and conceptualization of this version of the paper	directed the writing and conceptualization of this version of the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Supervision|Writing - Original Draft	YES
4104298	25043380	Key Affected Populations	2	conceptualized the idea for the longer, white paper version of this article	conceptualized the idea for the longer, white paper version of this article	Conceived and designed the experiments	Conceptualization	YES
4104298	25043380	Working Group	2	conceptualized the idea for the longer, white paper version of this article	conceptualized the idea for the longer, white paper version of this article	Conceived and designed the experiments	Conceptualization	YES
5100182	27821060	CMaher	2	provided supervision	provided supervision	-	Supervision	YES
5100182	27821060	CMiller	2	created the fishplot package|wrote the manuscript and created the figures	created the fishplot package	-	-	NO
5100182	27821060	CMiller	2	created the fishplot package|wrote the manuscript and created the figures	wrote the manuscript and created the figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5100182	27821060	EM	2	edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5100182	27821060	HD	2	contributed code and testing	contributed code and testing	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5100182	27821060	JM	2	designed the original fish plots	designed the original fish plots	Conceived and designed the experiments	-	YES
5100182	27821060	LD	2	designed the original fish plots|edited the manuscript	designed the original fish plots	Conceived and designed the experiments	-	YES
5100182	27821060	LD	2	designed the original fish plots|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5100182	27821060	RW	2	provided supervision|secured funding	provided supervision	-	Supervision	YES
5100182	27821060	RW	2	provided supervision|secured funding	secured funding	-	Funding acquisition	YES
5100182	27821060	TL	2	designed the original fish plots|edited the manuscript	designed the original fish plots	Conceived and designed the experiments	-	YES
5100182	27821060	TL	2	designed the original fish plots|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5470171	28659952	DB	2	provided assistance with crossing and genotyping experiments	provided assistance with crossing and genotyping experiments	Performed the experiments	Investigation	YES
5470171	28659952	EP	2	contributed with the and wrote the article with	contributed with the and wrote the article with	Wrote the paper	Writing - Original Draft	YES
5470171	28659952	GB	2	contributed with the and wrote the article with	contributed with the and wrote the article with	Wrote the paper	Writing - Original Draft	YES
5470171	28659952	KS	2	planned and performed most of the experiments, analyzed the data, and wrote the article with	planned and performed most of the experiments, analyzed the data, and wrote the article with	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
5470171	28659952	KV	2	contributed with the and wrote the article with|supervised the research	contributed with the and wrote the article with	Wrote the paper	Writing - Original Draft	YES
5470171	28659952	KV	2	contributed with the and wrote the article with|supervised the research	supervised the research	-	Supervision	YES
5470171	28659952	LV	2	contributed with the and wrote the article with	contributed with the and wrote the article with	Wrote the paper	Writing - Original Draft	YES
5470171	28659952	MM	2	performed next generation sequencing	performed next generation sequencing	Performed the experiments	Investigation	YES
5470171	28659952	MZ	2	provided assistance with crossing and genotyping experiments	provided assistance with crossing and genotyping experiments	Performed the experiments	Investigation	YES
5470171	28659952	TB	2	contributed with the and wrote the article with	contributed with the and wrote the article with	Wrote the paper	Writing - Original Draft	YES
3993899	24620710	G.R.A.W.	2	contributed equally to this work	contributed equally to this work	-	-	NO
3993899	24620710	N.J.S.	2	contributed equally to this work	contributed equally to this work	-	-	NO
4401454	25886133	EM	PLoS5	Conceived and designed the experiments|Wrote the paper|Interpreted the results	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401454	25886133	EM	PLoS5	Conceived and designed the experiments|Wrote the paper|Interpreted the results	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401454	25886133	EM	PLoS5	Conceived and designed the experiments|Wrote the paper|Interpreted the results	Interpreted the results	Analyzed the data	Formal analysis	YES
4401454	25886133	FNZ	PLoS5	Analyzed the data|Wrote the paper|Interpreted the results	Analyzed the data	Analyzed the data	Formal analysis	YES
4401454	25886133	FNZ	PLoS5	Analyzed the data|Wrote the paper|Interpreted the results	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401454	25886133	FNZ	PLoS5	Analyzed the data|Wrote the paper|Interpreted the results	Interpreted the results	Analyzed the data	Formal analysis	YES
4401454	25886133	IMZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Performed literature search|Quality analysis|Interpreted the results	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401454	25886133	IMZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Performed literature search|Quality analysis|Interpreted the results	Analyzed the data	Analyzed the data	Formal analysis	YES
4401454	25886133	IMZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Performed literature search|Quality analysis|Interpreted the results	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401454	25886133	IMZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Performed literature search|Quality analysis|Interpreted the results	Performed literature search	Performed the experiments	Formal analysis|Investigation	YES
4401454	25886133	IMZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Performed literature search|Quality analysis|Interpreted the results	Quality analysis	-	-	NO
4401454	25886133	IMZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Performed literature search|Quality analysis|Interpreted the results	Interpreted the results	Analyzed the data	Formal analysis	YES
4401454	25886133	PDZ	PLoS5	Wrote the paper|Interpreted the results	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401454	25886133	PDZ	PLoS5	Wrote the paper|Interpreted the results	Interpreted the results	Analyzed the data	Formal analysis	YES
4401454	25886133	SP	PLoS5	Conceived and designed the experiments|Wrote the paper|Performed literature search|Quality analysis|Interpreted the results	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401454	25886133	SP	PLoS5	Conceived and designed the experiments|Wrote the paper|Performed literature search|Quality analysis|Interpreted the results	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401454	25886133	SP	PLoS5	Conceived and designed the experiments|Wrote the paper|Performed literature search|Quality analysis|Interpreted the results	Performed literature search	Performed the experiments	Formal analysis|Investigation	YES
4401454	25886133	SP	PLoS5	Conceived and designed the experiments|Wrote the paper|Performed literature search|Quality analysis|Interpreted the results	Quality analysis	-	-	NO
4401454	25886133	SP	PLoS5	Conceived and designed the experiments|Wrote the paper|Performed literature search|Quality analysis|Interpreted the results	Interpreted the results	Analyzed the data	Formal analysis	YES
4401455	25886152	ECF	PLoS5	Performed the experiments|Took part in the concept and design of the study and critically reviewed the draft manuscript, providing a major intellectual contribution to the final version|Read and approved the final manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4401455	25886152	ECF	PLoS5	Performed the experiments|Took part in the concept and design of the study and critically reviewed the draft manuscript, providing a major intellectual contribution to the final version|Read and approved the final manuscript	Took part in the concept and design of the study and critically reviewed the draft manuscript, providing a major intellectual contribution to the final version	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
4401455	25886152	ECF	PLoS5	Performed the experiments|Took part in the concept and design of the study and critically reviewed the draft manuscript, providing a major intellectual contribution to the final version|Read and approved the final manuscript	Read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4401455	25886152	FJMS	PLoS5	Performed the experiments|Took part in the concept and design of the study and critically reviewed the draft manuscript, providing a major intellectual contribution to the final version|Read and approved the final manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4401455	25886152	FJMS	PLoS5	Performed the experiments|Took part in the concept and design of the study and critically reviewed the draft manuscript, providing a major intellectual contribution to the final version|Read and approved the final manuscript	Took part in the concept and design of the study and critically reviewed the draft manuscript, providing a major intellectual contribution to the final version	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
4401455	25886152	FJMS	PLoS5	Performed the experiments|Took part in the concept and design of the study and critically reviewed the draft manuscript, providing a major intellectual contribution to the final version|Read and approved the final manuscript	Read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4401455	25886152	FJNM	PLoS5	Took part in the concept and design of the study and critically reviewed the draft manuscript, providing a major intellectual contribution to the final version|Read and approved the final manuscript	Took part in the concept and design of the study and critically reviewed the draft manuscript, providing a major intellectual contribution to the final version	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
4401455	25886152	FJNM	PLoS5	Took part in the concept and design of the study and critically reviewed the draft manuscript, providing a major intellectual contribution to the final version|Read and approved the final manuscript	Read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4401455	25886152	ILP	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Took part in the original concept and design of this study and drafted the initial manuscript|Read and approved the final manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401455	25886152	ILP	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Took part in the original concept and design of this study and drafted the initial manuscript|Read and approved the final manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4401455	25886152	ILP	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Took part in the original concept and design of this study and drafted the initial manuscript|Read and approved the final manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401455	25886152	ILP	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Took part in the original concept and design of this study and drafted the initial manuscript|Read and approved the final manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401455	25886152	ILP	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Took part in the original concept and design of this study and drafted the initial manuscript|Read and approved the final manuscript	Took part in the original concept and design of this study and drafted the initial manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
4401455	25886152	ILP	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Took part in the original concept and design of this study and drafted the initial manuscript|Read and approved the final manuscript	Read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4401455	25886152	JCM	PLoS5	Took part in the concept and design of the study and critically reviewed the draft manuscript, providing a major intellectual contribution to the final version|Read and approved the final manuscript	Took part in the concept and design of the study and critically reviewed the draft manuscript, providing a major intellectual contribution to the final version	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
4401455	25886152	JCM	PLoS5	Took part in the concept and design of the study and critically reviewed the draft manuscript, providing a major intellectual contribution to the final version|Read and approved the final manuscript	Read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4401455	25886152	JCMH	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401455	25886152	JCMH	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401455	25886152	JCMH	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401455	25886152	JMMA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Took part in the concept and design of the study and critically reviewed the draft manuscript, providing a major intellectual contribution to the final version|Read and approved the final manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401455	25886152	JMMA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Took part in the concept and design of the study and critically reviewed the draft manuscript, providing a major intellectual contribution to the final version|Read and approved the final manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4401455	25886152	JMMA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Took part in the concept and design of the study and critically reviewed the draft manuscript, providing a major intellectual contribution to the final version|Read and approved the final manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401455	25886152	JMMA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Took part in the concept and design of the study and critically reviewed the draft manuscript, providing a major intellectual contribution to the final version|Read and approved the final manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401455	25886152	JMMA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Took part in the concept and design of the study and critically reviewed the draft manuscript, providing a major intellectual contribution to the final version|Read and approved the final manuscript	Took part in the concept and design of the study and critically reviewed the draft manuscript, providing a major intellectual contribution to the final version	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
4401455	25886152	JMMA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Took part in the concept and design of the study and critically reviewed the draft manuscript, providing a major intellectual contribution to the final version|Read and approved the final manuscript	Read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4401455	25886152	MCFG	PLoS5	Performed the experiments|Took part in the concept and design of the study and critically reviewed the draft manuscript, providing a major intellectual contribution to the final version|Read and approved the final manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4401455	25886152	MCFG	PLoS5	Performed the experiments|Took part in the concept and design of the study and critically reviewed the draft manuscript, providing a major intellectual contribution to the final version|Read and approved the final manuscript	Took part in the concept and design of the study and critically reviewed the draft manuscript, providing a major intellectual contribution to the final version	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
4401455	25886152	MCFG	PLoS5	Performed the experiments|Took part in the concept and design of the study and critically reviewed the draft manuscript, providing a major intellectual contribution to the final version|Read and approved the final manuscript	Read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4401455	25886152	SKU	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Took part in the concept and design of the study and critically reviewed the draft manuscript, providing a major intellectual contribution to the final version|Read and approved the final manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4401455	25886152	SKU	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Took part in the concept and design of the study and critically reviewed the draft manuscript, providing a major intellectual contribution to the final version|Read and approved the final manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401455	25886152	SKU	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Took part in the concept and design of the study and critically reviewed the draft manuscript, providing a major intellectual contribution to the final version|Read and approved the final manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401455	25886152	SKU	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Took part in the concept and design of the study and critically reviewed the draft manuscript, providing a major intellectual contribution to the final version|Read and approved the final manuscript	Took part in the concept and design of the study and critically reviewed the draft manuscript, providing a major intellectual contribution to the final version	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
4401455	25886152	SKU	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Took part in the concept and design of the study and critically reviewed the draft manuscript, providing a major intellectual contribution to the final version|Read and approved the final manuscript	Read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4401455	25886152	YLP	PLoS5	Performed the experiments|Took part in the concept and design of the study and critically reviewed the draft manuscript, providing a major intellectual contribution to the final version|Read and approved the final manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4401455	25886152	YLP	PLoS5	Performed the experiments|Took part in the concept and design of the study and critically reviewed the draft manuscript, providing a major intellectual contribution to the final version|Read and approved the final manuscript	Took part in the concept and design of the study and critically reviewed the draft manuscript, providing a major intellectual contribution to the final version	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
4401455	25886152	YLP	PLoS5	Performed the experiments|Took part in the concept and design of the study and critically reviewed the draft manuscript, providing a major intellectual contribution to the final version|Read and approved the final manuscript	Read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
3362036	22675271	E. B. Assayag	2	equally contributed to this work	equally contributed to this work	-	-	NO
3362036	22675271	M. Mijajlovic	2	equally contributed to this work	equally contributed to this work	-	-	NO
4107316	25053452	The authors	2	have equally been involved in drafting the viewpoint|jointly wrote and edited the manuscript	have equally been involved in drafting the viewpoint	Wrote the paper	Writing - Original Draft	YES
4107316	25053452	The authors	2	have equally been involved in drafting the viewpoint|jointly wrote and edited the manuscript	jointly wrote and edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
2637286	19102742	AA	2	participated in the conception and design, analysis and interpretation of data, critical revision of the manuscript, and supervision	participated in the conception and design, analysis and interpretation of data, critical revision of the manuscript, and supervision	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Supervision|Writing - Review & Editing	YES
2637286	19102742	AG	2	participated in the conception and design, analysis and interpretation of data, drafting of the manuscript, critical revision of the manuscript, administrative support and supervision	participated in the conception and design, analysis and interpretation of data, drafting of the manuscript, critical revision of the manuscript, administrative support and supervision	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Project administration|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
2637286	19102742	DQ	2	participated in analysis and interpretation of data, drafting the manuscript, and material support	participated in analysis and interpretation of data, drafting the manuscript, and material support	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
2637286	19102742	IC	2	participated in the conception and design, analysis and interpretation of data, drafting of the manuscript, critical revision of the manuscript and supervision	participated in the conception and design, analysis and interpretation of data, drafting of the manuscript, critical revision of the manuscript and supervision	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
2637286	19102742	WBJ	2	participated in the conception and design, analysis and interpretation of data, critical revision of the manuscript, obtaining funding and supervision	participated in the conception and design, analysis and interpretation of data, critical revision of the manuscript, obtaining funding and supervision	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Funding acquisition|Supervision|Writing - Review & Editing	YES
5100183	27821059	JFC	2	carried out the experiment, performed molecular work and data analysis|designed the study	carried out the experiment, performed molecular work and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5100183	27821059	JFC	2	carried out the experiment, performed molecular work and data analysis|designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5100183	27821059	KJFV	2	contributed to methylation data analysis|designed the study	contributed to methylation data analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5100183	27821059	KJFV	2	contributed to methylation data analysis|designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5100183	27821059	NW	2	prepared bisulfite libraries	prepared bisulfite libraries	-	-	NO
5100183	27821059	TvG	2	contributed to methylation data analysis	contributed to methylation data analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5100183	27821059	VdJ	2	helped with the bioinformatics analysis	helped with the bioinformatics analysis	-	Formal analysis	YES
5470526	28659949	AX	2	carried out gene cloning and expression	carried out gene cloning and expression	Performed the experiments	Investigation	YES
5470526	28659949	All authors	2	have read and approved the content of the manuscript	have read and approved the content of the manuscript	-	-	NO
5470526	28659949	BZ	2	collected important background information and provided assistance for data acquisition, data analysis and statistical analysis	collected important background information and provided assistance for data acquisition, data analysis and statistical analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5470526	28659949	FL	2	collected important background information and provided assistance for data acquisition, data analysis and statistical analysis	collected important background information and provided assistance for data acquisition, data analysis and statistical analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5470526	28659949	JaD	2	collected important background information and provided assistance for data acquisition, data analysis and statistical analysis	collected important background information and provided assistance for data acquisition, data analysis and statistical analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5470526	28659949	JuD	2	carried out the qtl mapping of salt tolerance	carried out the qtl mapping of salt tolerance	Performed the experiments	Investigation	YES
5470526	28659949	LL	2	carried out the qtl mapping of salt tolerance	carried out the qtl mapping of salt tolerance	Performed the experiments	Investigation	YES
5470526	28659949	MQ	2	collected important background information and provided assistance for data acquisition, data analysis and statistical analysis	collected important background information and provided assistance for data acquisition, data analysis and statistical analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5470526	28659949	NZ	2	carried out the data analysis and manuscript preparation	carried out the data analysis and manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5470526	28659949	XL	2	collected important background information and provided assistance for data acquisition, data analysis and statistical analysis	collected important background information and provided assistance for data acquisition, data analysis and statistical analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5470526	28659949	YL	2	carried out the data analysis and manuscript preparation	carried out the data analysis and manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5470526	28659949	YW	2	collected important background information and provided assistance for data acquisition, data analysis and statistical analysis	collected important background information and provided assistance for data acquisition, data analysis and statistical analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5470526	28659949	YZ	2	carried out the data analysis and manuscript preparation	carried out the data analysis and manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5470526	28659949	ZH	2	was responsible for designing this study and drafting the manuscript	was responsible for designing this study and drafting the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5470526	28659949	ZT	2	carried out the data analysis and manuscript preparation	carried out the data analysis and manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4110379	25059653	JJA	2	conceived and wrote the article	conceived and wrote the article	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4401456	25884205	BGD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401456	25884205	BGD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401456	25884205	BGD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401456	25884205	BGD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401456	25884205	BGD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401456	25884205	BW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401456	25884205	BW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401456	25884205	BW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401456	25884205	BW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401456	25884205	BW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401456	25884205	CTA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401456	25884205	CTA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401456	25884205	CTA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401456	25884205	GC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401456	25884205	GC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401456	25884205	GC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401456	25884205	GC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401456	25884205	JLP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401456	25884205	JLP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401456	25884205	JLP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401456	25884205	JLP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401456	25884205	TLR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401456	25884205	TLR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401456	25884205	TLR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2644707	19193217	BAJ	2	performed the studies that quantified oxidant stress in the hiv-1 transgenic rats	performed the studies that quantified oxidant stress in the hiv-1 transgenic rats	Performed the experiments	Investigation	YES
2644707	19193217	DPJ	2	performed the studies that quantified oxidant stress in the hiv-1 transgenic rats	performed the studies that quantified oxidant stress in the hiv-1 transgenic rats	Performed the experiments	Investigation	YES
2644707	19193217	MK	2	performed the immunocytochemistry for occludin and zo-1 protein localization in alveolar epithelial monolayers in vitro	performed the immunocytochemistry for occludin and zo-1 protein localization in alveolar epithelial monolayers in vitro	Performed the experiments	Investigation	YES
2644707	19193217	PCJ	2	determined alveolar epithelial cell permeability in vitro	determined alveolar epithelial cell permeability in vitro	Performed the experiments	Investigation	YES
2644707	19193217	RLS	2	performed the studies that quantified oxidant stress in the hiv-1 transgenic rats	performed the studies that quantified oxidant stress in the hiv-1 transgenic rats	Performed the experiments	Investigation	YES
2644707	19193217	XF	2	determined tight junction gene and protein expression	determined tight junction gene and protein expression	Performed the experiments	Investigation	YES
4116617	25079438	All authors	2	provided critical input to subsequent drafts and approved the final version	provided critical input to subsequent drafts and approved the final version	Wrote the paper	Writing - Original Draft	YES
4116617	25079438	NF	2	wrote the first draft	wrote the first draft	Wrote the paper	Writing - Original Draft	YES
5471298	28663754	FC	2	helped in the design of the study and the collection of plant materials	helped in the design of the study and the collection of plant materials	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5471298	28663754	HL	2	conducted the experiments and prepared the manuscript	conducted the experiments and prepared the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5471298	28663754	TY	2	participated in the design and helped to draft the manuscript	participated in the design and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
5471298	28663754	YC	2	participated in the design and helped to draft the manuscript	participated in the design and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
5100190	27821055	AC	PLoS52	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5100190	27821055	AD	PLoS52	contributed reagents/materials/analysis tools	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5100190	27821055	AK	PLoS52	generated and analyzed the data	generated and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5100190	27821055	All authors	PLoS52	read, edited and approved the manuscript for publication	read, edited and approved the manuscript for publication	Wrote the paper	Writing - Review & Editing	YES
5100190	27821055	CBM	PLoS52	contributed reagents/materials/analysis tools	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5100190	27821055	EC	PLoS52	contributed reagents/materials/analysis tools	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5100190	27821055	GC	PLoS52	conceived and designed the study|generated and analyzed the data|wrote the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5100190	27821055	GC	PLoS52	conceived and designed the study|generated and analyzed the data|wrote the manuscript	generated and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5100190	27821055	GC	PLoS52	conceived and designed the study|generated and analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5100190	27821055	KSW	PLoS52	conceived and designed the study|generated and analyzed the data	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5100190	27821055	KSW	PLoS52	conceived and designed the study|generated and analyzed the data	generated and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5100190	27821055	LT	PLoS52	contributed reagents/materials/analysis tools	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5100190	27821055	MD	PLoS52	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5100190	27821055	PJK	PLoS52	contributed reagents/materials/analysis tools	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4438154	26064961	P. Claes	2	is therefore a joint last author	is therefore a joint last author	-	-	NO
4116618	25079437	ACK	2	contributed to the concept and design of the study	contributed to the concept and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4116618	25079437	ADH	2	contributed to the concept and design of the study|contributed to data analysis and/or interpretation of the data|reviewed and suggested revisions	contributed to the concept and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4116618	25079437	ADH	2	contributed to the concept and design of the study|contributed to data analysis and/or interpretation of the data|reviewed and suggested revisions	contributed to data analysis and/or interpretation of the data	Analyzed the data	Formal analysis	YES
4116618	25079437	ADH	2	contributed to the concept and design of the study|contributed to data analysis and/or interpretation of the data|reviewed and suggested revisions	reviewed and suggested revisions	Wrote the paper	Writing - Review & Editing	YES
4116618	25079437	AKC	2	reviewed and suggested revisions	reviewed and suggested revisions	Wrote the paper	Writing - Review & Editing	YES
4116618	25079437	AM	2	contributed to data analysis and/or interpretation of the data|reviewed and suggested revisions	contributed to data analysis and/or interpretation of the data	Analyzed the data	Formal analysis	YES
4116618	25079437	AM	2	contributed to data analysis and/or interpretation of the data|reviewed and suggested revisions	reviewed and suggested revisions	Wrote the paper	Writing - Review & Editing	YES
4116618	25079437	All authors	2	reviewed and approved the final manuscript	reviewed and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4116618	25079437	GM	2	contributed to acquisition of data|reviewed and suggested revisions	contributed to acquisition of data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4116618	25079437	GM	2	contributed to acquisition of data|reviewed and suggested revisions	reviewed and suggested revisions	Wrote the paper	Writing - Review & Editing	YES
4116618	25079437	IM	2	contributed to acquisition of data|reviewed and suggested revisions	contributed to acquisition of data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4116618	25079437	IM	2	contributed to acquisition of data|reviewed and suggested revisions	reviewed and suggested revisions	Wrote the paper	Writing - Review & Editing	YES
4116618	25079437	JvO	2	contributed to data analysis and/or interpretation of the data|drafted the manuscript	contributed to data analysis and/or interpretation of the data	Analyzed the data	Formal analysis	YES
4116618	25079437	JvO	2	contributed to data analysis and/or interpretation of the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4116618	25079437	ML	2	contributed to the concept and design of the study|reviewed and suggested revisions	contributed to the concept and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4116618	25079437	ML	2	contributed to the concept and design of the study|reviewed and suggested revisions	reviewed and suggested revisions	Wrote the paper	Writing - Review & Editing	YES
4116618	25079437	MvL	2	contributed to the concept and design of the study|contributed to acquisition of data|contributed to data analysis and/or interpretation of the data|drafted the manuscript	contributed to the concept and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4116618	25079437	MvL	2	contributed to the concept and design of the study|contributed to acquisition of data|contributed to data analysis and/or interpretation of the data|drafted the manuscript	contributed to acquisition of data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4116618	25079437	MvL	2	contributed to the concept and design of the study|contributed to acquisition of data|contributed to data analysis and/or interpretation of the data|drafted the manuscript	contributed to data analysis and/or interpretation of the data	Analyzed the data	Formal analysis	YES
4116618	25079437	MvL	2	contributed to the concept and design of the study|contributed to acquisition of data|contributed to data analysis and/or interpretation of the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4116618	25079437	RB	2	contributed to the concept and design of the study|contributed to data analysis and/or interpretation of the data|drafted the manuscript	contributed to the concept and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4116618	25079437	RB	2	contributed to the concept and design of the study|contributed to data analysis and/or interpretation of the data|drafted the manuscript	contributed to data analysis and/or interpretation of the data	Analyzed the data	Formal analysis	YES
4116618	25079437	RB	2	contributed to the concept and design of the study|contributed to data analysis and/or interpretation of the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4116618	25079437	SC	2	reviewed and suggested revisions	reviewed and suggested revisions	Wrote the paper	Writing - Review & Editing	YES
4116618	25079437	TB	2	contributed to acquisition of data|reviewed and suggested revisions	contributed to acquisition of data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4116618	25079437	TB	2	contributed to acquisition of data|reviewed and suggested revisions	reviewed and suggested revisions	Wrote the paper	Writing - Review & Editing	YES
4116618	25079437	VvS	2	contributed to acquisition of data|reviewed and suggested revisions	contributed to acquisition of data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4116618	25079437	VvS	2	contributed to acquisition of data|reviewed and suggested revisions	reviewed and suggested revisions	Wrote the paper	Writing - Review & Editing	YES
2653546	19196474	BC	2	participated in drafting, critical review, and revision of the manuscript	participated in drafting, critical review, and revision of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
2653546	19196474	CC	2	participated in the study design and was involved in manuscript reviews	participated in the study design and was involved in manuscript reviews	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
2653546	19196474	CF	2	was involved in the study design, acquisition of data and the review of the manuscript	was involved in the study design, acquisition of data and the review of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
2653546	19196474	CKa	2	participated in the review of the manuscript	participated in the review of the manuscript	Wrote the paper	Writing - Review & Editing	YES
2653546	19196474	CKo	2	reviewed and critiqued the drafts of the manuscript	reviewed and critiqued the drafts of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
2653546	19196474	CT	2	provided substantial contribution to the study concepts, analyzed and interpreted data and assisted in drafting and revising the manuscript	provided substantial contribution to the study concepts, analyzed and interpreted data and assisted in drafting and revising the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Resources|Writing - Original Draft|Writing - Review & Editing	YES
2653546	19196474	JS	2	contributed to the study design, critically reviewed and revised the manuscript	contributed to the study design, critically reviewed and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
2653546	19196474	MF	2	contributed to the study concepts, interpretation of data and provided critical comment on drafts of the manuscript	contributed to the study concepts, interpretation of data and provided critical comment on drafts of the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Resources|Writing - Original Draft	YES
2653546	19196474	MY	2	contributed to the multi-disciplinary group that synthesized the data from the study into a cohesive form, gave oral presentations on the study and helped produce the written work	contributed to the multi-disciplinary group that synthesized the data from the study into a cohesive form, gave oral presentations on the study and helped produce the written work	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Resources|Writing - Original Draft	YES
2653546	19196474	PS	2	participated in the interpretation of data, critical review and revisions to the manuscript	participated in the interpretation of data, critical review and revisions to the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
2653546	19196474	RH	2	was the academic lead on the project|provided the conceptual basis for the development of study materials, interpreted data and critically revised the first draft of the manuscript	was the academic lead on the project	-	-	NO
2653546	19196474	RH	2	was the academic lead on the project|provided the conceptual basis for the development of study materials, interpreted data and critically revised the first draft of the manuscript	provided the conceptual basis for the development of study materials, interpreted data and critically revised the first draft of the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Resources|Writing - Original Draft|Writing - Review & Editing	YES
2653546	19196474	RK	2	contributed to the study design advisory board and reviewed drafts of the manuscript	contributed to the study design advisory board and reviewed drafts of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft|Writing - Review & Editing	YES
2653546	19196474	VC	2	performed the statistical analysis of the data and contributed to the drafting, critical review and revisions of the manuscript	performed the statistical analysis of the data and contributed to the drafting, critical review and revisions of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5471321	28663755	AS	2	discussed results and wrote the manuscript	discussed results and wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5471321	28663755	EG	2	discussed results and wrote the manuscript	discussed results and wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5471321	28663755	EL	2	discussed results and wrote the manuscript	discussed results and wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5471321	28663755	HN	2	provided rna seq expression data and discussed results	provided rna seq expression data and discussed results	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5471321	28663755	LS	2	provided rna seq expression data and discussed results	provided rna seq expression data and discussed results	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5100196	27821047	BA	PLoS52	designed, implemented the method, performed the experiments and analysed the result|wrote the paper	designed, implemented the method, performed the experiments and analysed the result	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5100196	27821047	BA	PLoS52	designed, implemented the method, performed the experiments and analysed the result|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5100196	27821047	JC	PLoS52	conceived the idea and supervised the project|wrote the paper	conceived the idea and supervised the project	Conceived and designed the experiments	Conceptualization|Supervision	YES
5100196	27821047	JC	PLoS52	conceived the idea and supervised the project|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5100196	27821047	TT	PLoS52	designed, implemented the method, performed the experiments and analysed the result|wrote the paper	designed, implemented the method, performed the experiments and analysed the result	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5100196	27821047	TT	PLoS52	designed, implemented the method, performed the experiments and analysed the result|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401457	25885272	EDL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401457	25885272	EDL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401457	25885272	EDL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401457	25885272	EDL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401457	25885272	NAC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401457	25885272	NAC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401457	25885272	NAC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401457	25885272	NAC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401457	25885272	NB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401457	25885272	NB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401457	25885272	NB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2672933	19358725	AF	2	participated in the conception and design of the study, analysis, and interpretation of the data, and development of the manuscript	participated in the conception and design of the study, analysis, and interpretation of the data, and development of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
2672933	19358725	AL	2	participated in the analysis of the data and development of the manuscript	participated in the analysis of the data and development of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
2672933	19358725	DM	2	participated in the conception and design of the study, analysis, and interpretation of the data, and development of the manuscript	participated in the conception and design of the study, analysis, and interpretation of the data, and development of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
2672933	19358725	ED	2	participated in the analysis of the data and development of the manuscript	participated in the analysis of the data and development of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
2672933	19358725	MS	2	participated in the conception and design of the study, analysis, and interpretation of the data, and development of the manuscript	participated in the conception and design of the study, analysis, and interpretation of the data, and development of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
2672933	19358725	PNK	2	participated in the analysis and interpretation of the data and the development of the manuscript	participated in the analysis and interpretation of the data and the development of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
2672933	19358725	PP	2	participated in the analysis and interpretation of the data and the development of the manuscript	participated in the analysis and interpretation of the data and the development of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
2672933	19358725	PS	2	participated in the analysis of the data and development of the manuscript	participated in the analysis of the data and development of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4119288	25085002	ACM	2	conceived and designed the study, were responsible for study coordination and data management, helped analyze data, interpreted findings and wrote the manuscript	conceived and designed the study, were responsible for study coordination and data management, helped analyze data, interpreted findings and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Data curation|Formal analysis|Methodology|Project administration|Writing - Original Draft	YES
4119288	25085002	AD	2	assisted in reviewing the protocol and study coordination in the field, contributed to data management and reviewed the manuscript	assisted in reviewing the protocol and study coordination in the field, contributed to data management and reviewed the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Data curation|Methodology|Project administration|Writing - Review & Editing	YES
4119288	25085002	CN	2	assisted in statistical analysis, interpretation and manuscript writing	assisted in statistical analysis, interpretation and manuscript writing	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4119288	25085002	CS	2	assisted in statistical analysis, interpretation and manuscript writing	assisted in statistical analysis, interpretation and manuscript writing	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4119288	25085002	MHK	2	conceived and designed the study, were responsible for study coordination and data management, helped analyze data, interpreted findings and wrote the manuscript	conceived and designed the study, were responsible for study coordination and data management, helped analyze data, interpreted findings and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Data curation|Formal analysis|Methodology|Project administration|Writing - Original Draft	YES
4119288	25085002	PNK	2	reviewed the study protocol, provided guidance on the conduct of the study and critically reviewed the manuscript for important intellectual content	reviewed the study protocol, provided guidance on the conduct of the study and critically reviewed the manuscript for important intellectual content	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Supervision|Writing - Review & Editing	YES
4119288	25085002	SA	2	reviewed the study protocol, provided guidance on the conduct of the study and critically reviewed the manuscript for important intellectual content	reviewed the study protocol, provided guidance on the conduct of the study and critically reviewed the manuscript for important intellectual content	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Supervision|Writing - Review & Editing	YES
4119288	25085002	XY	2	assisted in statistical analysis, interpretation and manuscript writing	assisted in statistical analysis, interpretation and manuscript writing	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5471329	28663752	AHP	2	helped in experimental setup	helped in experimental setup	Performed the experiments	Investigation	YES
5471329	28663752	HG	2	helped in experimental setup	helped in experimental setup	Performed the experiments	Investigation	YES
5471329	28663752	IA	2	did the analysis and finalized the manuscript	did the analysis and finalized the manuscript	Wrote the paper	Writing - Review & Editing	YES
5471329	28663752	MF	2	did the analysis and finalized the manuscript	did the analysis and finalized the manuscript	Wrote the paper	Writing - Review & Editing	YES
5471329	28663752	MKA	2	did the analysis and finalized the manuscript	did the analysis and finalized the manuscript	Wrote the paper	Writing - Review & Editing	YES
5471329	28663752	PC	2	helped in experimental setup	helped in experimental setup	Performed the experiments	Investigation	YES
5471329	28663752	SM	2	designed the experiment and isolated the rna|did the analysis and finalized the manuscript	designed the experiment and isolated the rna	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5471329	28663752	SM	2	designed the experiment and isolated the rna|did the analysis and finalized the manuscript	did the analysis and finalized the manuscript	Wrote the paper	Writing - Review & Editing	YES
4401508	25884398	CAK	PLoS5	Wrote the paper|Data|Data|Support	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401508	25884398	CAK	PLoS5	Wrote the paper|Data|Data|Support	Data	-	-	NO
4401508	25884398	CAK	PLoS5	Wrote the paper|Data|Data|Support	Data	-	-	NO
4401508	25884398	CAK	PLoS5	Wrote the paper|Data|Data|Support	Support	-	-	NO
4401508	25884398	DHK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Data|Data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401508	25884398	DHK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Data|Data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401508	25884398	DHK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Data|Data	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401508	25884398	DHK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Data|Data	Data	-	-	NO
4401508	25884398	DHK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Data|Data	Data	-	-	NO
4401508	25884398	DHS	PLoS5	Wrote the paper|Data	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401508	25884398	DHS	PLoS5	Wrote the paper|Data	Data	-	-	NO
4401508	25884398	JRR	PLoS5	Wrote the paper|Data|Data|Support	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401508	25884398	JRR	PLoS5	Wrote the paper|Data|Data|Support	Data	-	-	NO
4401508	25884398	JRR	PLoS5	Wrote the paper|Data|Data|Support	Data	-	-	NO
4401508	25884398	JRR	PLoS5	Wrote the paper|Data|Data|Support	Support	-	-	NO
4401508	25884398	LAF	PLoS5	Wrote the paper|Data|Data|Support	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401508	25884398	LAF	PLoS5	Wrote the paper|Data|Data|Support	Data	-	-	NO
4401508	25884398	LAF	PLoS5	Wrote the paper|Data|Data|Support	Data	-	-	NO
4401508	25884398	LAF	PLoS5	Wrote the paper|Data|Data|Support	Support	-	-	NO
4401508	25884398	SCK	PLoS5	Conceived and designed the experiments|Wrote the paper|Data|Data|Support	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401508	25884398	SCK	PLoS5	Conceived and designed the experiments|Wrote the paper|Data|Data|Support	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401508	25884398	SCK	PLoS5	Conceived and designed the experiments|Wrote the paper|Data|Data|Support	Data	-	-	NO
4401508	25884398	SCK	PLoS5	Conceived and designed the experiments|Wrote the paper|Data|Data|Support	Data	-	-	NO
4401508	25884398	SCK	PLoS5	Conceived and designed the experiments|Wrote the paper|Data|Data|Support	Support	-	-	NO
3993925	24559479	All authors	2	have given approval to the final version of the manuscript	have given approval to the final version of the manuscript	-	-	NO
3993925	24559479	M.L.	2	contributed equally	contributed equally	-	-	NO
3993925	24559479	Y.H.	2	contributed equally	contributed equally	-	-	NO
4164229	25157679	B.I.F.	2	contributed equally to this work	contributed equally to this work	-	-	NO
4164229	25157679	D.L.	2	contributed equally to this work	contributed equally to this work	-	-	NO
4164229	25157679	V.S.	2	contributed equally to this work	contributed equally to this work	-	-	NO
2678152	19383117	ACB	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
2678152	19383117	CM	PLoS52	participated in developing the hypothesis and collaborated in the writing and reviewing of the article	participated in developing the hypothesis and collaborated in the writing and reviewing of the article	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
2678152	19383117	EvE	PLoS52	participated in developing the hypothesis and collaborated in the writing and reviewing of the article	participated in developing the hypothesis and collaborated in the writing and reviewing of the article	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
2678152	19383117	LK	PLoS52	participated in developing the hypothesis and collaborated in the writing and reviewing of the article	participated in developing the hypothesis and collaborated in the writing and reviewing of the article	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
2678152	19383117	LL	PLoS52	participated in developing the hypothesis and collaborated in the writing and reviewing of the article	participated in developing the hypothesis and collaborated in the writing and reviewing of the article	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
2678152	19383117	RC	PLoS52	participated in developing the hypothesis and collaborated in the writing and reviewing of the article	participated in developing the hypothesis and collaborated in the writing and reviewing of the article	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
2678152	19383117	RMR	PLoS52	participated in developing the hypothesis and collaborated in the writing and reviewing of the article	participated in developing the hypothesis and collaborated in the writing and reviewing of the article	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
5100198	27821073	LJ	2	designed the analysis for real data application	designed the analysis for real data application	Conceived and designed the experiments|Analyzed the data	Formal analysis	YES
5100198	27821073	MR	2	completed the simulations together	completed the simulations together	-	Formal analysis	YES
5100198	27821073	MX	2	proposed the model and drafted the manuscript|designed the analysis for real data application	proposed the model and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
5100198	27821073	MX	2	proposed the model and drafted the manuscript|designed the analysis for real data application	designed the analysis for real data application	Conceived and designed the experiments|Analyzed the data	Formal analysis	YES
5100198	27821073	PW	2	proposed the model and drafted the manuscript|implemented the model and carried out most of the real data analysis|completed the simulations together|designed the analysis for real data application	proposed the model and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
5100198	27821073	PW	2	proposed the model and drafted the manuscript|implemented the model and carried out most of the real data analysis|completed the simulations together|designed the analysis for real data application	implemented the model and carried out most of the real data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5100198	27821073	PW	2	proposed the model and drafted the manuscript|implemented the model and carried out most of the real data analysis|completed the simulations together|designed the analysis for real data application	completed the simulations together	-	Formal analysis	YES
5100198	27821073	PW	2	proposed the model and drafted the manuscript|implemented the model and carried out most of the real data analysis|completed the simulations together|designed the analysis for real data application	designed the analysis for real data application	Conceived and designed the experiments|Analyzed the data	Formal analysis	YES
4122815	25095830	ASP	2	conceived the study, acquired data and critically revised the manuscript	conceived the study, acquired data and critically revised the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Review & Editing	YES
4122815	25095830	DPW	2	conceived the study, contributed to study design and critically revised the manuscript	conceived the study, contributed to study design and critically revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
4122815	25095830	HCW	2	contributed to the interpretation of data and critically revised the manuscript	contributed to the interpretation of data and critically revised the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
4122815	25095830	KAM	2	contributed to study design, performed all analyses and wrote the manuscript	contributed to study design, performed all analyses and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4122815	25095830	SRG	2	conceived the study, acquired data and critically revised the manuscript	conceived the study, acquired data and critically revised the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Review & Editing	YES
5318336	28063021	A Hammel	2	made substantial contributions to the acquisition, analysis, and interpretation of the data	made substantial contributions to the acquisition, analysis, and interpretation of the data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5318336	28063021	All authors	2	participated in drafting the article or critical revision for important intellectual content, provided final approval of the version to be published, and agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the article are appropriately investigated and resolved	participated in drafting the article or critical revision for important intellectual content, provided final approval of the version to be published, and agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the article are appropriately investigated and resolved	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5318336	28063021	Each author	2	participated and contributed sufficiently to take public responsibility for appropriate portions of the content	participated and contributed sufficiently to take public responsibility for appropriate portions of the content	-	-	NO
5318336	28063021	N Wehr	2	made substantial contributions to the acquisition, analysis, and interpretation of the data	made substantial contributions to the acquisition, analysis, and interpretation of the data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5318336	28063021	P West	2	made substantial contributions to study conception and design as well as the acquisition, analysis, and interpretation of the data	made substantial contributions to study conception and design as well as the acquisition, analysis, and interpretation of the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Methodology|Resources	YES
5318336	28063021	R Arabyat	2	made substantial contributions to the acquisition, analysis, and interpretation of the data	made substantial contributions to the acquisition, analysis, and interpretation of the data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5471331	28663756	HA	PLoS52	processed the omics data and performed bioinformatics analysis|wrote the paper	processed the omics data and performed bioinformatics analysis	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5471331	28663756	HA	PLoS52	processed the omics data and performed bioinformatics analysis|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5471331	28663756	HK	PLoS52	designed the project|designed and conducted the drought experiments	designed the project	Conceived and designed the experiments	Methodology	YES
5471331	28663756	HK	PLoS52	designed the project|designed and conducted the drought experiments	designed and conducted the drought experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5471331	28663756	IJ	PLoS52	processed the omics data and performed bioinformatics analysis|wrote the paper	processed the omics data and performed bioinformatics analysis	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5471331	28663756	IJ	PLoS52	processed the omics data and performed bioinformatics analysis|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5471331	28663756	JK	PLoS52	provided oserf71 transgenic rice seeds	provided oserf71 transgenic rice seeds	Performed the experiments	Investigation	YES
5471331	28663756	SK	PLoS52	designed the project|wrote the paper	designed the project	Conceived and designed the experiments	Methodology	YES
5471331	28663756	SK	PLoS52	designed the project|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5471331	28663756	SR	PLoS52	performed mirna analysis	performed mirna analysis	Performed the experiments	Investigation	YES
5471331	28663756	SS	PLoS52	designed and conducted the drought experiments	designed and conducted the drought experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5471331	28663756	WJ	PLoS52	interpreted the network analysis results biologically|wrote the paper	interpreted the network analysis results biologically	Analyzed the data	Formal analysis	YES
5471331	28663756	WJ	PLoS52	interpreted the network analysis results biologically|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
2679059	19397788	AA	1	Conception and design|Final approval of the article	Conception and design	Conceived and designed the experiments	Conceptualization	YES
2679059	19397788	AA	1	Conception and design|Final approval of the article	Final approval of the article	-	-	NO
2679059	19397788	DS	1	Conception and design|Collection and assembly of data|Analysis and interpretation of the data	Conception and design	Conceived and designed the experiments	Conceptualization	YES
2679059	19397788	DS	1	Conception and design|Collection and assembly of data|Analysis and interpretation of the data	Collection and assembly of data	Performed the experiments	Investigation	YES
2679059	19397788	DS	1	Conception and design|Collection and assembly of data|Analysis and interpretation of the data	Analysis and interpretation of the data	Analyzed the data	Formal analysis	YES
2679059	19397788	EPM	1	Revision of the different versions of the study protocol|Quality control of the data	Revision of the different versions of the study protocol	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
2679059	19397788	EPM	1	Revision of the different versions of the study protocol|Quality control of the data	Quality control of the data	Performed the experiments	Validation	YES
2679059	19397788	FM	1	Quality control of the data|Analysis and interpretation of the data	Quality control of the data	Performed the experiments	Validation	YES
2679059	19397788	FM	1	Quality control of the data|Analysis and interpretation of the data	Analysis and interpretation of the data	Analyzed the data	Formal analysis	YES
2679059	19397788	JGA	1	Critical revision of the article for important intellectual contents	Critical revision of the article for important intellectual contents	Wrote the paper	Writing - Review & Editing	YES
2679059	19397788	JLP	1	Final approval of the article	Final approval of the article	-	-	NO
2679059	19397788	JO	1	Conception and design|Revision of the different versions of the study protocol|Quality control of the data|Analysis and interpretation of the data|Drafting of the article|Final approval of the article	Conception and design	Conceived and designed the experiments	Conceptualization	YES
2679059	19397788	JO	1	Conception and design|Revision of the different versions of the study protocol|Quality control of the data|Analysis and interpretation of the data|Drafting of the article|Final approval of the article	Revision of the different versions of the study protocol	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
2679059	19397788	JO	1	Conception and design|Revision of the different versions of the study protocol|Quality control of the data|Analysis and interpretation of the data|Drafting of the article|Final approval of the article	Quality control of the data	Performed the experiments	Validation	YES
2679059	19397788	JO	1	Conception and design|Revision of the different versions of the study protocol|Quality control of the data|Analysis and interpretation of the data|Drafting of the article|Final approval of the article	Analysis and interpretation of the data	Analyzed the data	Formal analysis	YES
2679059	19397788	JO	1	Conception and design|Revision of the different versions of the study protocol|Quality control of the data|Analysis and interpretation of the data|Drafting of the article|Final approval of the article	Drafting of the article	Wrote the paper	Writing - Original Draft	YES
2679059	19397788	JO	1	Conception and design|Revision of the different versions of the study protocol|Quality control of the data|Analysis and interpretation of the data|Drafting of the article|Final approval of the article	Final approval of the article	-	-	NO
2679059	19397788	JT	1	Conception and design|Final approval of the article	Conception and design	Conceived and designed the experiments	Conceptualization	YES
2679059	19397788	JT	1	Conception and design|Final approval of the article	Final approval of the article	-	-	NO
4401509	25885695	CY	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401509	25885695	CZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401509	25885695	JC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401509	25885695	JC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401509	25885695	JL	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401509	25885695	QX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401509	25885695	QX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401509	25885695	QX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401509	25885695	QX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401509	25885695	QX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4176387	25148906	H.C.	2	contributed equally to this work	contributed equally to this work	-	-	NO
4176387	25148906	J.F.	2	contributed equally to this work	contributed equally to this work	-	-	NO
4122816	25095831	DG	2	conceived the study design|conducted the searches, screening, data extraction and analysis|wrote the first draft|commented on all subsequent drafts	conceived the study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4122816	25095831	DG	2	conceived the study design|conducted the searches, screening, data extraction and analysis|wrote the first draft|commented on all subsequent drafts	conducted the searches, screening, data extraction and analysis	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
4122816	25095831	DG	2	conceived the study design|conducted the searches, screening, data extraction and analysis|wrote the first draft|commented on all subsequent drafts	wrote the first draft	Wrote the paper	Writing - Original Draft	YES
4122816	25095831	DG	2	conceived the study design|conducted the searches, screening, data extraction and analysis|wrote the first draft|commented on all subsequent drafts	commented on all subsequent drafts	Wrote the paper	Writing - Original Draft	YES
4122816	25095831	EKN	2	conceived the study design|commented on all subsequent drafts	conceived the study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4122816	25095831	EKN	2	conceived the study design|commented on all subsequent drafts	commented on all subsequent drafts	Wrote the paper	Writing - Original Draft	YES
4122816	25095831	JM	2	wrote the first draft|commented on all subsequent drafts	wrote the first draft	Wrote the paper	Writing - Original Draft	YES
4122816	25095831	JM	2	wrote the first draft|commented on all subsequent drafts	commented on all subsequent drafts	Wrote the paper	Writing - Original Draft	YES
4122816	25095831	KK	2	conceived the study design|conducted the searches, screening, data extraction and analysis|wrote the first draft|commented on all subsequent drafts	conceived the study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4122816	25095831	KK	2	conceived the study design|conducted the searches, screening, data extraction and analysis|wrote the first draft|commented on all subsequent drafts	conducted the searches, screening, data extraction and analysis	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
4122816	25095831	KK	2	conceived the study design|conducted the searches, screening, data extraction and analysis|wrote the first draft|commented on all subsequent drafts	wrote the first draft	Wrote the paper	Writing - Original Draft	YES
4122816	25095831	KK	2	conceived the study design|conducted the searches, screening, data extraction and analysis|wrote the first draft|commented on all subsequent drafts	commented on all subsequent drafts	Wrote the paper	Writing - Original Draft	YES
4122816	25095831	NF	2	commented on all subsequent drafts	commented on all subsequent drafts	Wrote the paper	Writing - Original Draft	YES
4122816	25095831	RCB	2	conceived the study design|commented on all subsequent drafts	conceived the study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4122816	25095831	RCB	2	conceived the study design|commented on all subsequent drafts	commented on all subsequent drafts	Wrote the paper	Writing - Original Draft	YES
5100228	27821044	BA	PLoS52	designed research and analyzed data	designed research and analyzed data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5100228	27821044	BM	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5100228	27821044	CP	PLoS52	conducted experiments	conducted experiments	Performed the experiments	Investigation	YES
5100228	27821044	ES	PLoS52	designed research and analyzed data	designed research and analyzed data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5100228	27821044	FI	PLoS52	conducted experiments	conducted experiments	Performed the experiments	Investigation	YES
5100228	27821044	MAF	PLoS52	conducted experiments	conducted experiments	Performed the experiments	Investigation	YES
5100228	27821044	RAG	PLoS52	designed research and analyzed data|conducted experiments|wrote the paper	designed research and analyzed data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5100228	27821044	RAG	PLoS52	designed research and analyzed data|conducted experiments|wrote the paper	conducted experiments	Performed the experiments	Investigation	YES
5100228	27821044	RAG	PLoS52	designed research and analyzed data|conducted experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5100228	27821044	SA	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5100228	27821044	WZ	PLoS52	designed research and analyzed data|wrote the paper	designed research and analyzed data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5100228	27821044	WZ	PLoS52	designed research and analyzed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5471333	28663753	AS	7	this author participated of the data analyses and manuscript writing	this author participated of the data analyses and manuscript writing	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5471333	28663753	JD	7	this author participated of the experimental design, laboratory work and data analyses	this author participated of the experimental design, laboratory work and data analyses	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5471333	28663753	LY	7	this author contributed with the experimental design, laboratory work, data analyses, result discussion and text writing	this author contributed with the experimental design, laboratory work, data analyses, result discussion and text writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
5471333	28663753	MS	7	this author contributed with data analyses, results discussion and manuscript writing	this author contributed with data analyses, results discussion and manuscript writing	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
5471333	28663753	PS	7	this author contributed with data analyses, results discussion and manuscript writing	this author contributed with data analyses, results discussion and manuscript writing	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
5471333	28663753	VR	7	this author contributed with the experimental design, data analyses, results discussion and text writing	this author contributed with the experimental design, data analyses, results discussion and text writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
2681471	19400929	BR	2	carried out the field work	carried out the field work	Performed the experiments	Investigation	YES
2681471	19400929	CM	2	created the database	created the database	Contributed reagents/materials/analysis tools	Software	YES
2681471	19400929	COC	2	carried out the statistical analysis|prepared the manuscript|prepared the study design	carried out the statistical analysis	Analyzed the data	Formal analysis	YES
2681471	19400929	COC	2	carried out the statistical analysis|prepared the manuscript|prepared the study design	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
2681471	19400929	COC	2	carried out the statistical analysis|prepared the manuscript|prepared the study design	prepared the study design	Conceived and designed the experiments	Methodology	YES
2681471	19400929	DM	2	carried out the field work	carried out the field work	Performed the experiments	Investigation	YES
2681471	19400929	GM	2	carried out the field work	carried out the field work	Performed the experiments	Investigation	YES
2681471	19400929	JS	2	carried out the statistical analysis	carried out the statistical analysis	Analyzed the data	Formal analysis	YES
2681471	19400929	KP	2	carried out the field work	carried out the field work	Performed the experiments	Investigation	YES
2681471	19400929	KS	2	carried out the field work|were guarantors of the study	carried out the field work	Performed the experiments	Investigation	YES
2681471	19400929	KS	2	carried out the field work|were guarantors of the study	were guarantors of the study	-	-	NO
2681471	19400929	MC	2	carried out the field work|prepared the manuscript|created the database|prepared the study design	carried out the field work	Performed the experiments	Investigation	YES
2681471	19400929	MC	2	carried out the field work|prepared the manuscript|created the database|prepared the study design	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
2681471	19400929	MC	2	carried out the field work|prepared the manuscript|created the database|prepared the study design	created the database	Contributed reagents/materials/analysis tools	Software	YES
2681471	19400929	MC	2	carried out the field work|prepared the manuscript|created the database|prepared the study design	prepared the study design	Conceived and designed the experiments	Methodology	YES
2681471	19400929	MOC	2	carried out the statistical analysis|prepared the manuscript	carried out the statistical analysis	Analyzed the data	Formal analysis	YES
2681471	19400929	MOC	2	carried out the statistical analysis|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
2681471	19400929	RL	2	were guarantors of the study	were guarantors of the study	-	-	NO
4127809	25109284	AAC	2	assisted with data collection, manuscript writing and patients care	assisted with data collection, manuscript writing and patients care	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4127809	25109284	DWF	2	assisted with study design, data analysis, and manuscript writing	assisted with study design, data analysis, and manuscript writing	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4127809	25109284	JAD	2	conceived, designed, and executed the study, analyzed the data, and wrote the manuscript	conceived, designed, and executed the study, analyzed the data, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4127809	25109284	JS	2	provided microbiological technical inputs, analyzed the data and wrote the manuscript	provided microbiological technical inputs, analyzed the data and wrote the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
4127809	25109284	KAM	2	conceived, designed, and executed the study, analyzed the data, and wrote the manuscript	conceived, designed, and executed the study, analyzed the data, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4127809	25109284	SEK	2	conceived, designed, and executed the study, analyzed the data, and wrote the manuscript	conceived, designed, and executed the study, analyzed the data, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4127809	25109284	SWK	2	assisted with data collection, manuscript writing and patients care	assisted with data collection, manuscript writing and patients care	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4401510	25885114	CHY	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401510	25885114	DHS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401510	25885114	DKK	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401510	25885114	ESK	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401510	25885114	GK	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401510	25885114	HJK	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401510	25885114	HKL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401510	25885114	Heebal Kim	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401510	25885114	Hyeongmin Kim	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401510	25885114	Hyeongmin Kim	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401510	25885114	Hyeongmin Kim	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401510	25885114	Hyunil Kim	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401510	25885114	JDO	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401510	25885114	JKH	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401510	25885114	Jaemin Kim	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401510	25885114	Jaemin Kim	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401510	25885114	Jiho Kim	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401510	25885114	KC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401510	25885114	KDS	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401510	25885114	KSS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401510	25885114	KTL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401510	25885114	KYE	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401510	25885114	NK	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401510	25885114	SC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401510	25885114	SM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401510	25885114	SP	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401510	25885114	SS	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401510	25885114	THK	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401510	25885114	TL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401510	25885114	WCP	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401510	25885114	WK	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4401510	25885114	WK	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401510	25885114	WKL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401510	25885114	YK	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5472673	28670323	CL	7	participated to design the work, interpreted seedling data for the work; and revised it critically for important intellectual content; and approved the final version to be published; and agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	participated to design the work, interpreted seedling data for the work; and revised it critically for important intellectual content; and approved the final version to be published; and agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Data curation|Formal analysis|Writing - Review & Editing	YES
5472673	28670323	EB	7	designed the work, analyzed, interpreted seedling data for the work; and drafted the work; and approved the final version to be published; and agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	designed the work, analyzed, interpreted seedling data for the work; and drafted the work; and approved the final version to be published; and agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Data curation|Formal analysis|Writing - Original Draft	YES
5472673	28670323	FV	7	acquisited, analyzed seedling data for the work; and revised critically for important intellectual content; and approved the final version to be published; and agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	acquisited, analyzed seedling data for the work; and revised critically for important intellectual content; and approved the final version to be published; and agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Analyzed the data|Wrote the paper	Data curation|Formal analysis|Writing - Review & Editing	YES
5100263	27821050	AA	2	wrote perl scripts to identify sox10 binding sites|designed, performed and analyzed all of the remaining data|wrote the manuscript	wrote perl scripts to identify sox10 binding sites	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Software|Writing - Original Draft	YES
5100263	27821050	AA	2	wrote perl scripts to identify sox10 binding sites|designed, performed and analyzed all of the remaining data|wrote the manuscript	designed, performed and analyzed all of the remaining data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5100263	27821050	AA	2	wrote perl scripts to identify sox10 binding sites|designed, performed and analyzed all of the remaining data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5100263	27821050	ABP	2	designed and wrote the exactplus program to examine multiple-species alignments	designed and wrote the exactplus program to examine multiple-species alignments	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Software|Writing - Original Draft	YES
5100263	27821050	CG	2	designed, performed and analyzed all of the remaining data|wrote the manuscript	designed, performed and analyzed all of the remaining data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5100263	27821050	CG	2	designed, performed and analyzed all of the remaining data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5100263	27821050	GC	2	designed and performed dnase-seq experiments	designed and performed dnase-seq experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5100263	27821050	JCM	2	designed and wrote the exactplus program to examine multiple-species alignments	designed and wrote the exactplus program to examine multiple-species alignments	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Software|Writing - Original Draft	YES
5100263	27821050	JFR-M	2	designed and performed qrt-pcr experiments	designed and performed qrt-pcr experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5100263	27821050	JS	2	designed and performed qrt-pcr experiments|wrote the manuscript	designed and performed qrt-pcr experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5100263	27821050	JS	2	designed and performed qrt-pcr experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5100263	27821050	LS	2	designed and performed dnase-seq experiments	designed and performed dnase-seq experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5100263	27821050	WDL	2	wrote perl scripts to identify sox10 binding sites|designed, performed and analyzed all of the remaining data|wrote the manuscript	wrote perl scripts to identify sox10 binding sites	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Software|Writing - Original Draft	YES
5100263	27821050	WDL	2	wrote perl scripts to identify sox10 binding sites|designed, performed and analyzed all of the remaining data|wrote the manuscript	designed, performed and analyzed all of the remaining data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5100263	27821050	WDL	2	wrote perl scripts to identify sox10 binding sites|designed, performed and analyzed all of the remaining data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
2684870	19386130	EP	7	Designed the study, participated in the experiments, interpreted and analyzed the data, and drafted the manuscript	Designed the study, participated in the experiments, interpreted and analyzed the data, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
2684870	19386130	GED	7	Designed the study, participated in the experiments, interpreted and analyzed the data, and reviewed the drafted manuscript	Designed the study, participated in the experiments, interpreted and analyzed the data, and reviewed the drafted manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
2684870	19386130	SPG	7	Designed the study, participated in the experiments, interpreted and analyzed the data, and reviewed the drafted manuscript	Designed the study, participated in the experiments, interpreted and analyzed the data, and reviewed the drafted manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
2684870	19386130	YCC	7	Designed the study, supervised the experiments, interpreted the data, and reviewed the drafted manuscript	Designed the study, supervised the experiments, interpreted the data, and reviewed the drafted manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
4401511	25885452	BW	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4401511	25885452	BW	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401511	25885452	IT	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401511	25885452	IT	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401511	25885452	JEG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401511	25885452	JEG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401511	25885452	JEG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401511	25885452	JEG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401511	25885452	KEH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401511	25885452	KEH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4401511	25885452	KEH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401511	25885452	NGC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401511	25885452	NGC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401511	25885452	NGC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401511	25885452	NGC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401511	25885452	SAC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401511	25885452	SAC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401511	25885452	SAC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401511	25885452	SAC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401511	25885452	SLC	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4439476	26064877	Jing Sun	2	contributed equally to this work	contributed equally to this work	-	-	NO
4439476	26064877	Yongsen Wang	2	contributed equally to this work	contributed equally to this work	-	-	NO
4203386	25250848	All authors	2	have given approval to the final version of the manuscript	have given approval to the final version of the manuscript	-	-	NO
5100273	27821053	AS	2	performed laboratory work	performed laboratory work	Performed the experiments	Investigation	YES
5100273	27821053	EFW	2	assisted with data analysis and interpretation	assisted with data analysis and interpretation	Analyzed the data	Formal analysis	YES
5100273	27821053	JEK	2	assisted with data analysis and interpretation	assisted with data analysis and interpretation	Analyzed the data	Formal analysis	YES
5100273	27821053	JR	2	conceived and coordinated the study	conceived and coordinated the study	Conceived and designed the experiments	Conceptualization|Project administration	YES
5100273	27821053	LK	2	performed data and statistical analyses	performed data and statistical analyses	Analyzed the data	Formal analysis	YES
5100273	27821053	LM	2	was instrumental in the utilization of the episnpmpi program	was instrumental in the utilization of the episnpmpi program	-	-	NO
5100273	27821053	MM	2	performed laboratory work	performed laboratory work	Performed the experiments	Investigation	YES
5100273	27821053	NW	2	performed data and statistical analyses	performed data and statistical analyses	Analyzed the data	Formal analysis	YES
5100273	27821053	all authors	2	reviewed and contributed to the draft of the manuscript	reviewed and contributed to the draft of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5472680	28670319	CB	PLoS52	conceived and designed the experiments|wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5472680	28670319	CB	PLoS52	conceived and designed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5472680	28670319	DC	PLoS52	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5472680	28670319	FY	PLoS52	conceived and designed the experiments|performed the experiments and analyzed the data|wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5472680	28670319	FY	PLoS52	conceived and designed the experiments|performed the experiments and analyzed the data|wrote the manuscript	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5472680	28670319	FY	PLoS52	conceived and designed the experiments|performed the experiments and analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5472680	28670319	JB	PLoS52	conceived and designed the experiments|wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5472680	28670319	JB	PLoS52	conceived and designed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5472680	28670319	XY	PLoS52	conceived and designed the experiments|performed the experiments and analyzed the data	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5472680	28670319	XY	PLoS52	conceived and designed the experiments|performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5472680	28670319	ZH	PLoS52	conceived and designed the experiments|wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5472680	28670319	ZH	PLoS52	conceived and designed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4134669	25128907	AI	2	performed the serological tests|contributed to writing the manuscript	performed the serological tests	Performed the experiments	Investigation	YES
4134669	25128907	AI	2	performed the serological tests|contributed to writing the manuscript	contributed to writing the manuscript	Wrote the paper	Writing - Original Draft	YES
4134669	25128907	AM	2	enrolled the patients and supervised the study on clinical sites	enrolled the patients and supervised the study on clinical sites	Performed the experiments	Investigation|Supervision	YES
4134669	25128907	All authors	2	contributed to the critical review of the manuscript	contributed to the critical review of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4134669	25128907	BT	2	performed the statistical analysis, interpreted the results and drafted the manuscript	performed the statistical analysis, interpreted the results and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4134669	25128907	CK	2	enrolled the patients and supervised the study on clinical sites|contributed to writing the manuscript	enrolled the patients and supervised the study on clinical sites	Performed the experiments	Investigation|Supervision	YES
4134669	25128907	CK	2	enrolled the patients and supervised the study on clinical sites|contributed to writing the manuscript	contributed to writing the manuscript	Wrote the paper	Writing - Original Draft	YES
4134669	25128907	DH	2	enrolled the patients and supervised the study on clinical sites	enrolled the patients and supervised the study on clinical sites	Performed the experiments	Investigation|Supervision	YES
4134669	25128907	DKE	2	designed the study|contributed to writing the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
4134669	25128907	DKE	2	designed the study|contributed to writing the manuscript	contributed to writing the manuscript	Wrote the paper	Writing - Original Draft	YES
4134669	25128907	DM	2	enrolled the patients and supervised the study on clinical sites	enrolled the patients and supervised the study on clinical sites	Performed the experiments	Investigation|Supervision	YES
4134669	25128907	EM	2	enrolled the patients and supervised the study on clinical sites	enrolled the patients and supervised the study on clinical sites	Performed the experiments	Investigation|Supervision	YES
4134669	25128907	FD	2	contributed to writing the manuscript	contributed to writing the manuscript	Wrote the paper	Writing - Original Draft	YES
4134669	25128907	GB	2	enrolled the patients and supervised the study on clinical sites	enrolled the patients and supervised the study on clinical sites	Performed the experiments	Investigation|Supervision	YES
4134669	25128907	PAC	2	helped for specific analysis and data interpretation|contributed to writing the manuscript	helped for specific analysis and data interpretation	Analyzed the data	Formal analysis	YES
4134669	25128907	PAC	2	helped for specific analysis and data interpretation|contributed to writing the manuscript	contributed to writing the manuscript	Wrote the paper	Writing - Original Draft	YES
4134669	25128907	SPE	2	contributed to writing the manuscript	contributed to writing the manuscript	Wrote the paper	Writing - Original Draft	YES
2686733	19439092	ASD	2	conceived of the study design and was responsible for its conduct	conceived of the study design and was responsible for its conduct	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
2686733	19439092	FJP	2	participated in the design of the study, assisted with its execution, and assisted with the interpretation of the data	participated in the design of the study, assisted with its execution, and assisted with the interpretation of the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
2686733	19439092	JBM	2	participated in the design of the study, assisted with its execution and provided administrative and intellectual support for the study	participated in the design of the study, assisted with its execution and provided administrative and intellectual support for the study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Project administration	YES
2686733	19439092	JS	2	helped draft the manuscript and assisted with database management	helped draft the manuscript and assisted with database management	Contributed reagents/materials/analysis tools|Wrote the paper	Software|Writing - Original Draft	YES
2686733	19439092	LAK	2	participated in the design of the study, assisted with its execution, and assisted with the interpretation of the data	participated in the design of the study, assisted with its execution, and assisted with the interpretation of the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
2686733	19439092	MDW	2	provided administrative and intellectual support for the study	provided administrative and intellectual support for the study	-	Project administration	YES
2686733	19439092	MJ	2	performed the statistical analysis and helped draft the manuscript	performed the statistical analysis and helped draft the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
2686733	19439092	TTB	2	drafted the manuscript and directed the statistical analysis	drafted the manuscript and directed the statistical analysis	Analyzed the data|Wrote the paper	Formal analysis|Supervision|Writing - Original Draft	YES
2686733	19439092	XX	2	performed the statistical analysis and helped draft the manuscript	performed the statistical analysis and helped draft the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4439479	26064905	Fangyan Wang	2	equally contributed to this work	equally contributed to this work	-	-	NO
4439479	26064905	Jing Sun	2	equally contributed to this work	equally contributed to this work	-	-	NO
4401513	25885092	ES	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401513	25885092	ES	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401513	25885092	ES	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401513	25885092	JR	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401513	25885092	JR	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401513	25885092	MF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401513	25885092	MF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401513	25885092	MF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401513	25885092	MF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401513	25885092	PM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401513	25885092	PM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401513	25885092	PM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401513	25885092	PM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401513	25885092	PM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401513	25885092	SG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401513	25885092	SG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401513	25885092	SG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401513	25885092	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401513	25885092	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401513	25885092	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401513	25885092	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401513	25885092	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5100337	27821061	AB	2	designed the study and drafted the manuscript|constructed rad-sequencing libraries|analyzed data	designed the study and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5100337	27821061	AB	2	designed the study and drafted the manuscript|constructed rad-sequencing libraries|analyzed data	constructed rad-sequencing libraries	Performed the experiments	Investigation	YES
5100337	27821061	AB	2	designed the study and drafted the manuscript|constructed rad-sequencing libraries|analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5100337	27821061	All authors	2	contributed to manuscript finalization and read and approved the final manuscript	contributed to manuscript finalization and read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5100337	27821061	CAW	2	constructed rad-sequencing libraries	constructed rad-sequencing libraries	Performed the experiments	Investigation	YES
4136415	25131801	AK	2	performed the statistical analyess	performed the statistical analyess	Analyzed the data	Formal analysis	YES
4136415	25131801	AM	2	contributed to the design of the study, the collection of data, and reviewed the manuscript	contributed to the design of the study, the collection of data, and reviewed the manuscript	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Methodology|Resources|Writing - Review & Editing	YES
4136415	25131801	BSM	2	conceptualized and constructed the database and reviewed the manuscript	conceptualized and constructed the database and reviewed the manuscript	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Investigation|Software|Writing - Review & Editing	YES
4136415	25131801	CTY	2	performed statistical analyses and wrote the manuscript	performed statistical analyses and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4136415	25131801	JJL	2	developed much of the underlying statistical theory and reviewed the manuscript	developed much of the underlying statistical theory and reviewed the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
4136415	25131801	KKW-K	2	lent clinical insight to the implications of the results	lent clinical insight to the implications of the results	-	-	NO
4136415	25131801	RJB	2	developed much of the underlying statistical theory and reviewed the manuscript	developed much of the underlying statistical theory and reviewed the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5472683	28670321	AG	2	contributed with experiment developing and critical review	contributed with experiment developing and critical review	Performed the experiments	Investigation	YES
5472683	28670321	CL	2	contributed with critical views	contributed with critical views	-	-	NO
5472683	28670321	DD	2	contributed in experimental planning and writing	contributed in experimental planning and writing	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology	YES
5472683	28670321	MG	2	evenly contributed to the manuscript in experiment developing and writing	evenly contributed to the manuscript in experiment developing and writing	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5472683	28670321	NM	2	evenly contributed to the manuscript in experiment developing and writing	evenly contributed to the manuscript in experiment developing and writing	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5472683	28670321	SD	2	contributed in experimental planning and writing	contributed in experimental planning and writing	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology	YES
2698819	19486507	All authors	2	have contributed to the hypothesis development, drafting and critically reviewing the manuscript	have contributed to the hypothesis development, drafting and critically reviewing the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
4401514	25885820	BET	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401514	25885820	BET	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401514	25885820	CL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401514	25885820	CL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401514	25885820	CL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401514	25885820	CL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401514	25885820	DZ	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401514	25885820	KW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401514	25885820	KW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401514	25885820	KW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401514	25885820	WC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401514	25885820	WC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401514	25885820	WC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401514	25885820	WC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401514	25885820	XL	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401514	25885820	XL	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401514	25885820	YX	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401514	25885820	YZ	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4139921	25141905	CL	2	have reviewed the manuscript	have reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
4139921	25141905	ML	2	reviewed the analysis plan and provided revisions to the manuscript	reviewed the analysis plan and provided revisions to the manuscript	Wrote the paper	Writing - Review & Editing	YES
4139921	25141905	MM	2	have reviewed the manuscript	have reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
4139921	25141905	PL	2	have reviewed the manuscript	have reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
4139921	25141905	PP	2	have reviewed the manuscript	have reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
4139921	25141905	RD	2	have reviewed the manuscript	have reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
4139921	25141905	RK	2	reviewed the analysis plan and provided revisions to the manuscript	reviewed the analysis plan and provided revisions to the manuscript	Wrote the paper	Writing - Review & Editing	YES
4139921	25141905	SK	2	originated concept ideas, reviewed the analysis plan and provided revisions to the manuscript	originated concept ideas, reviewed the analysis plan and provided revisions to the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
4139921	25141905	SS	2	reviewed the analysis plan and provided revisions to the manuscript	reviewed the analysis plan and provided revisions to the manuscript	Wrote the paper	Writing - Review & Editing	YES
4139921	25141905	TM	2	have reviewed the manuscript	have reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
4139921	25141905	TS	2	have reviewed the manuscript	have reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
4139921	25141905	WR	2	have reviewed the manuscript	have reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5472840	28670324	Both authors	2	reviewed litterature, contributed to writing the manuscript, and approved it for publication	reviewed litterature, contributed to writing the manuscript, and approved it for publication	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5100339	27821051	OPK	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5100339	27821051	XZ	2	collected and analyzed the genome mining data	collected and analyzed the genome mining data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4141908	24915468	AZ	PLoS52	carried out the in silico modelling	carried out the in silico modelling	Performed the experiments	Formal analysis|Investigation|Methodology	YES
4141908	24915468	All authors	PLoS52	commented on and made intellectual contributions to the manuscript at all stages of writing	commented on and made intellectual contributions to the manuscript at all stages of writing	Wrote the paper	Writing - Original Draft	YES
4141908	24915468	CS	PLoS52	carried out the in silico modelling	carried out the in silico modelling	Performed the experiments	Formal analysis|Investigation|Methodology	YES
4141908	24915468	DMT	PLoS52	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
4141908	24915468	HLB	PLoS52	carried out the experimental procedures|wrote the paper	carried out the experimental procedures	Performed the experiments	Investigation	YES
4141908	24915468	HLB	PLoS52	carried out the experimental procedures|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4141908	24915468	JBS	PLoS52	carried out the experimental procedures|carried out statistical analysis	carried out the experimental procedures	Performed the experiments	Investigation	YES
4141908	24915468	JBS	PLoS52	carried out the experimental procedures|carried out statistical analysis	carried out statistical analysis	Analyzed the data	Formal analysis	YES
4141908	24915468	LCG	PLoS52	designed the study|wrote the paper	designed the study	Conceived and designed the experiments	Methodology	YES
4141908	24915468	LCG	PLoS52	designed the study|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4141908	24915468	NGL	PLoS52	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
4141908	24915468	TBLK	PLoS52	carried out the in silico modelling	carried out the in silico modelling	Performed the experiments	Formal analysis|Investigation|Methodology	YES
1079909	15720727	Toshiyuki Homma	2	conceived the experimental design, carried out the experiment, and drafted the manuscript	conceived the experimental design, carried out the experiment, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Writing - Original Draft	YES
2701432	19505306	All authors	2	participated in the drafting of the manuscript	participated in the drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
4401515	25885288	BT	PLoS5	Conceived and designed the experiments|Manuscript review	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401515	25885288	BT	PLoS5	Conceived and designed the experiments|Manuscript review	Manuscript review	Wrote the paper	Writing - Review & Editing	YES
4401515	25885288	CO	PLoS5	Performed the experiments|Manuscript review	Performed the experiments	Performed the experiments	Investigation	YES
4401515	25885288	CO	PLoS5	Performed the experiments|Manuscript review	Manuscript review	Wrote the paper	Writing - Review & Editing	YES
4401515	25885288	CT	PLoS5	Performed the experiments|Manuscript review	Performed the experiments	Performed the experiments	Investigation	YES
4401515	25885288	CT	PLoS5	Performed the experiments|Manuscript review	Manuscript review	Wrote the paper	Writing - Review & Editing	YES
4401515	25885288	DK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Manuscript review	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401515	25885288	DK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Manuscript review	Analyzed the data	Analyzed the data	Formal analysis	YES
4401515	25885288	DK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Manuscript review	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401515	25885288	DK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Manuscript review	Manuscript review	Wrote the paper	Writing - Review & Editing	YES
4401515	25885288	EC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Quality control	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401515	25885288	EC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Quality control	Analyzed the data	Analyzed the data	Formal analysis	YES
4401515	25885288	EC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Quality control	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401515	25885288	EC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Quality control	Quality control	Performed the experiments	Validation	YES
4401515	25885288	HAL	PLoS5	Conceived and designed the experiments|Performed the experiments|Manuscript review	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401515	25885288	HAL	PLoS5	Conceived and designed the experiments|Performed the experiments|Manuscript review	Performed the experiments	Performed the experiments	Investigation	YES
4401515	25885288	HAL	PLoS5	Conceived and designed the experiments|Performed the experiments|Manuscript review	Manuscript review	Wrote the paper	Writing - Review & Editing	YES
4401515	25885288	QL	PLoS5	Analyzed the data|Wrote the paper|Quality control	Analyzed the data	Analyzed the data	Formal analysis	YES
4401515	25885288	QL	PLoS5	Analyzed the data|Wrote the paper|Quality control	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401515	25885288	QL	PLoS5	Analyzed the data|Wrote the paper|Quality control	Quality control	Performed the experiments	Validation	YES
4401515	25885288	TR	PLoS5	Conceived and designed the experiments|Manuscript review	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401515	25885288	TR	PLoS5	Conceived and designed the experiments|Manuscript review	Manuscript review	Wrote the paper	Writing - Review & Editing	YES
4401515	25885288	ZV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Quality control	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401515	25885288	ZV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Quality control	Performed the experiments	Performed the experiments	Investigation	YES
4401515	25885288	ZV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Quality control	Analyzed the data	Analyzed the data	Formal analysis	YES
4401515	25885288	ZV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Quality control	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401515	25885288	ZV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Quality control	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401515	25885288	ZV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Quality control	Quality control	Performed the experiments	Validation	YES
5472848	28670320	AL	2	contributed to analyses and manuscript production	contributed to analyses and manuscript production	Analyzed the data	Formal analysis	YES
5472848	28670320	CL	2	contributed to analyses and manuscript production	contributed to analyses and manuscript production	Analyzed the data	Formal analysis	YES
5472848	28670320	JB	2	contributed to analyses and manuscript production	contributed to analyses and manuscript production	Analyzed the data	Formal analysis	YES
5472848	28670320	JD	2	contributed to analyses and manuscript production	contributed to analyses and manuscript production	Analyzed the data	Formal analysis	YES
5472848	28670320	KH	2	contributed to analyses and manuscript production	contributed to analyses and manuscript production	Analyzed the data	Formal analysis	YES
5472848	28670320	KM	2	contributed to analyses and manuscript production	contributed to analyses and manuscript production	Analyzed the data	Formal analysis	YES
5472848	28670320	RF	2	supervised the research and edited the manuscript	supervised the research and edited the manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
5472848	28670320	SK	2	contributed to analyses and manuscript production	contributed to analyses and manuscript production	Analyzed the data	Formal analysis	YES
1079910	15790400	DCM	2	conceived the study and wrote the research grant	conceived the study and wrote the research grant	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
1079910	15790400	JPN	2	conceived the study and wrote the research grant|carried out the testing and data analysis of the study	conceived the study and wrote the research grant	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
1079910	15790400	JPN	2	conceived the study and wrote the research grant|carried out the testing and data analysis of the study	carried out the testing and data analysis of the study	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
1079910	15790400	YNB	2	participated in its design, coordination and provided the nirs equipment and expertise|carried out the testing and data analysis of the study	participated in its design, coordination and provided the nirs equipment and expertise	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Project administration|Resources	YES
1079910	15790400	YNB	2	participated in its design, coordination and provided the nirs equipment and expertise|carried out the testing and data analysis of the study	carried out the testing and data analysis of the study	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
2704235	19531211	All authors	2	critically reviewed and approved the final manuscript	critically reviewed and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
2704235	19531211	CV	2	assisted in designing the study and drafting the manuscript	assisted in designing the study and drafting the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
2704235	19531211	JP	2	provided substantial intellectual content to the manuscript	provided substantial intellectual content to the manuscript	-	-	NO
2704235	19531211	JR	2	performed viral loads and genotyping	performed viral loads and genotyping	Performed the experiments	Investigation	YES
2704235	19531211	JW	2	provided substantial intellectual content to the manuscript	provided substantial intellectual content to the manuscript	-	-	NO
2704235	19531211	KD	2	performed viral loads and genotyping	performed viral loads and genotyping	Performed the experiments	Investigation	YES
2704235	19531211	KS	2	designed the study, carried out molecular work and sequence analysis and prepared the manuscript	designed the study, carried out molecular work and sequence analysis and prepared the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
2704235	19531211	MT	2	provided substantial intellectual content to the manuscript	provided substantial intellectual content to the manuscript	-	-	NO
2704235	19531211	SL	2	assisted in designing the study and drafting the manuscript	assisted in designing the study and drafting the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4203393	25195494	L.X.	2	contributed equally to this work	contributed equally to this work	-	-	NO
4203393	25195494	V.G.V.	2	contributed equally to this work	contributed equally to this work	-	-	NO
3366219	22666170	A. A. Mutto	2	critically reviewed the paper	critically reviewed the paper	Wrote the paper	Writing - Review & Editing	YES
3366219	22666170	A. D. Barrera	2	critically reviewed the paper	critically reviewed the paper	Wrote the paper	Writing - Review & Editing	YES
3366219	22666170	D. Rodler	2	prepared the paper	prepared the paper	Wrote the paper	Writing - Original Draft	YES
3366219	22666170	F. Sinowatz	2	prepared the paper	prepared the paper	Wrote the paper	Writing - Original Draft	YES
3366219	22666170	G. A. Palma	2	prepared the paper	prepared the paper	Wrote the paper	Writing - Original Draft	YES
3366219	22666170	M. E. Arganaraz	2	collected and summarized articles	collected and summarized articles	Performed the experiments	Investigation	YES
5100661	27821058	DW	PLoS52	designed the research|performed the research|analyzed the data|wrote the article	designed the research	Conceived and designed the experiments	Methodology	YES
5100661	27821058	DW	PLoS52	designed the research|performed the research|analyzed the data|wrote the article	performed the research	Performed the experiments	Investigation	YES
5100661	27821058	DW	PLoS52	designed the research|performed the research|analyzed the data|wrote the article	analyzed the data	Analyzed the data	Formal analysis	YES
5100661	27821058	DW	PLoS52	designed the research|performed the research|analyzed the data|wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
5100661	27821058	FD	PLoS52	performed the research	performed the research	Performed the experiments	Investigation	YES
5100661	27821058	GZ	PLoS52	wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
5100661	27821058	LF	PLoS52	performed the research	performed the research	Performed the experiments	Investigation	YES
5100661	27821058	LJ	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5100661	27821058	QS	PLoS52	designed the research|performed the research|analyzed the data	designed the research	Conceived and designed the experiments	Methodology	YES
5100661	27821058	QS	PLoS52	designed the research|performed the research|analyzed the data	performed the research	Performed the experiments	Investigation	YES
5100661	27821058	QS	PLoS52	designed the research|performed the research|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5472854	28670322	HL	2	performed most of the experiments|designed the experiments and analyzed the data|conceived the project and wrote the article with contributions of all the authors	performed most of the experiments	Performed the experiments	Investigation	YES
5472854	28670322	HL	2	performed most of the experiments|designed the experiments and analyzed the data|conceived the project and wrote the article with contributions of all the authors	designed the experiments and analyzed the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5472854	28670322	HL	2	performed most of the experiments|designed the experiments and analyzed the data|conceived the project and wrote the article with contributions of all the authors	conceived the project and wrote the article with contributions of all the authors	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5472854	28670322	HZ	2	provided technical assistance to hl|conceived the project and wrote the article with contributions of all the authors	provided technical assistance to hl	Performed the experiments	Investigation	YES
5472854	28670322	HZ	2	provided technical assistance to hl|conceived the project and wrote the article with contributions of all the authors	conceived the project and wrote the article with contributions of all the authors	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5472854	28670322	LW	2	supervised and complemented the writing	supervised and complemented the writing	Wrote the paper	Supervision	YES
5472854	28670322	WX	2	conceived the original screening and research plans|supervised the experiment|designed the experiments and analyzed the data|conceived the project and wrote the article with contributions of all the authors|supervised and complemented the writing	conceived the original screening and research plans	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5472854	28670322	WX	2	conceived the original screening and research plans|supervised the experiment|designed the experiments and analyzed the data|conceived the project and wrote the article with contributions of all the authors|supervised and complemented the writing	supervised the experiment	-	Supervision	YES
5472854	28670322	WX	2	conceived the original screening and research plans|supervised the experiment|designed the experiments and analyzed the data|conceived the project and wrote the article with contributions of all the authors|supervised and complemented the writing	designed the experiments and analyzed the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5472854	28670322	WX	2	conceived the original screening and research plans|supervised the experiment|designed the experiments and analyzed the data|conceived the project and wrote the article with contributions of all the authors|supervised and complemented the writing	conceived the project and wrote the article with contributions of all the authors	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5472854	28670322	WX	2	conceived the original screening and research plans|supervised the experiment|designed the experiments and analyzed the data|conceived the project and wrote the article with contributions of all the authors|supervised and complemented the writing	supervised and complemented the writing	Wrote the paper	Supervision	YES
4141938	25148829	AMG	2	participated in the writing of the manuscript	participated in the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
4141938	25148829	EN	2	participated in the writing of the manuscript	participated in the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
4141938	25148829	LR	2	participated in the writing of the manuscript	participated in the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
4141938	25148829	PG	2	participated in the writing of the manuscript	participated in the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
1142518	15877822	AS	2	conceived, designed and coordinated the study, carried out the experiments, and drafted the manuscript	conceived, designed and coordinated the study, carried out the experiments, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Project administration|Writing - Original Draft	YES
1142518	15877822	JS	2	participated in the design and coordination of the study	participated in the design and coordination of the study	Conceived and designed the experiments	Methodology|Project administration	YES
1142518	15877822	MI	2	participated in the experiments	participated in the experiments	Performed the experiments	Investigation	YES
1142518	15877822	TY	2	participated in the design and coordination of the study, and directed it	participated in the design and coordination of the study, and directed it	Conceived and designed the experiments	Methodology|Project administration|Supervision	YES
4401516	25886477	CJZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401516	25886477	CJZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401516	25886477	CJZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401516	25886477	CJZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401516	25886477	DZQ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401516	25886477	HFC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401516	25886477	LMC	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401516	25886477	QNH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401516	25886477	SLY	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401516	25886477	WJH	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401516	25886477	XAZ	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401516	25886477	XJZ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401516	25886477	YQH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401516	25886477	ZHS	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401516	25886477	ZLY	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4060609	24901029	All authors	2	have given approval to the final version of the manuscript	have given approval to the final version of the manuscript	-	-	NO
1166570	15938748	AM	2	participated in the study design	participated in the study design	Conceived and designed the experiments	Methodology	YES
1166570	15938748	BB	2	participated in the coordination of the study	participated in the coordination of the study	-	Project administration	YES
1166570	15938748	CT	2	participated in the study design and coordinated the data collection	participated in the study design and coordinated the data collection	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Project administration	YES
1166570	15938748	EM	2	participated in the study design, performed the post-processing and statistical analysis	participated in the study design, performed the post-processing and statistical analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
1166570	15938748	RL	2	participated in the study design and coordinated the data collection	participated in the study design and coordinated the data collection	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Project administration	YES
1166570	15938748	SI	2	participated in the study design, coordinated the study, and drafted the manuscript	participated in the study design, coordinated the study, and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft	YES
5474485	28674548	All authors	2	listed have made a substantial, direct and intellectual contribution to the work, and approved it for publication	listed have made a substantial, direct and intellectual contribution to the work, and approved it for publication	-	-	NO
5474485	28674548	The authors	2	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	Performed the experiments	Investigation	YES
5101643	27825302	ASCz	2	prepared dna samples, performed mlpa and ddpcr assays, helped to analyze respective data and prepared input data for snp analysis	prepared dna samples, performed mlpa and ddpcr assays, helped to analyze respective data and prepared input data for snp analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5101643	27825302	AZ	2	conceived of the study, designed and oversaw all experiments	conceived of the study, designed and oversaw all experiments	Conceived and designed the experiments	Conceptualization|Methodology|Supervision	YES
5101643	27825302	MF	2	conceived of the study, interpreted the data, oversaw the research and finalized the manuscript	conceived of the study, interpreted the data, oversaw the research and finalized the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Supervision|Writing - Review & Editing	YES
5101643	27825302	MSz	2	carried out pcr assays and sanger sequencing experiments	carried out pcr assays and sanger sequencing experiments	Performed the experiments	Investigation	YES
5101643	27825302	PK	2	performed snp analysis and helped to draft the manuscript	performed snp analysis and helped to draft the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4145087	25160645	FC	2	jointly developed the initial conceptualization of the paper|refined the structure of the paper and its analytical strategy	jointly developed the initial conceptualization of the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4145087	25160645	FC	2	jointly developed the initial conceptualization of the paper|refined the structure of the paper and its analytical strategy	refined the structure of the paper and its analytical strategy	-	-	NO
4145087	25160645	JM	2	jointly developed the initial conceptualization of the paper|refined the structure of the paper and its analytical strategy	jointly developed the initial conceptualization of the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4145087	25160645	JM	2	jointly developed the initial conceptualization of the paper|refined the structure of the paper and its analytical strategy	refined the structure of the paper and its analytical strategy	-	-	NO
4145087	25160645	JR	2	jointly developed the initial conceptualization of the paper	jointly developed the initial conceptualization of the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4145087	25160645	R. All	2	authors agree to the final wording of the paper	authors agree to the final wording of the paper	-	-	NO
2708196	19519884	AO	2	made substantial contributions to manuscript content through subsequent drafts	made substantial contributions to manuscript content through subsequent drafts	Wrote the paper	Writing - Original Draft	YES
2708196	19519884	DE	2	made substantial contributions to manuscript content through subsequent drafts|participated in data collection at the various centers	made substantial contributions to manuscript content through subsequent drafts	Wrote the paper	Writing - Original Draft	YES
2708196	19519884	DE	2	made substantial contributions to manuscript content through subsequent drafts|participated in data collection at the various centers	participated in data collection at the various centers	Performed the experiments	Investigation	YES
2708196	19519884	EL	2	made substantial contributions to manuscript content through subsequent drafts|participated in data collection at the various centers	made substantial contributions to manuscript content through subsequent drafts	Wrote the paper	Writing - Original Draft	YES
2708196	19519884	EL	2	made substantial contributions to manuscript content through subsequent drafts|participated in data collection at the various centers	participated in data collection at the various centers	Performed the experiments	Investigation	YES
2708196	19519884	FS	2	made substantial contributions to manuscript content through subsequent drafts|participated in data collection at the various centers	made substantial contributions to manuscript content through subsequent drafts	Wrote the paper	Writing - Original Draft	YES
2708196	19519884	FS	2	made substantial contributions to manuscript content through subsequent drafts|participated in data collection at the various centers	participated in data collection at the various centers	Performed the experiments	Investigation	YES
2708196	19519884	HIV	2	vascular cohort study	vascular cohort study	-	-	NO
2708196	19519884	JB	2	made substantial contributions to manuscript content through subsequent drafts	made substantial contributions to manuscript content through subsequent drafts	Wrote the paper	Writing - Original Draft	YES
2708196	19519884	JG	2	made substantial contributions to manuscript content through subsequent drafts|participated in data collection at the various centers	made substantial contributions to manuscript content through subsequent drafts	Wrote the paper	Writing - Original Draft	YES
2708196	19519884	JG	2	made substantial contributions to manuscript content through subsequent drafts|participated in data collection at the various centers	participated in data collection at the various centers	Performed the experiments	Investigation	YES
2708196	19519884	KG	2	made substantial contributions to manuscript content through subsequent drafts|participated in data collection at the various centers	made substantial contributions to manuscript content through subsequent drafts	Wrote the paper	Writing - Original Draft	YES
2708196	19519884	KG	2	made substantial contributions to manuscript content through subsequent drafts|participated in data collection at the various centers	participated in data collection at the various centers	Performed the experiments	Investigation	YES
2708196	19519884	LT	2	made substantial contributions to manuscript content through subsequent drafts	made substantial contributions to manuscript content through subsequent drafts	Wrote the paper	Writing - Original Draft	YES
2708196	19519884	MS	2	made substantial contributions to manuscript content through subsequent drafts|participated in data collection at the various centers	made substantial contributions to manuscript content through subsequent drafts	Wrote the paper	Writing - Original Draft	YES
2708196	19519884	MS	2	made substantial contributions to manuscript content through subsequent drafts|participated in data collection at the various centers	participated in data collection at the various centers	Performed the experiments	Investigation	YES
2708196	19519884	SS	2	made substantial contributions to manuscript content through subsequent drafts|participated in data collection at the various centers	made substantial contributions to manuscript content through subsequent drafts	Wrote the paper	Writing - Original Draft	YES
2708196	19519884	SS	2	made substantial contributions to manuscript content through subsequent drafts|participated in data collection at the various centers	participated in data collection at the various centers	Performed the experiments	Investigation	YES
2708196	19519884	TA	2	made substantial contributions to manuscript content through subsequent drafts|participated in data collection at the various centers	made substantial contributions to manuscript content through subsequent drafts	Wrote the paper	Writing - Original Draft	YES
2708196	19519884	TA	2	made substantial contributions to manuscript content through subsequent drafts|participated in data collection at the various centers	participated in data collection at the various centers	Performed the experiments	Investigation	YES
5641923	28688576	DRJV	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5641923	28688576	GFM	2	contributed to vamp8-/- experiments	contributed to vamp8-/- experiments	Performed the experiments	Investigation	YES
5641923	28688576	GvdB	2	designed experiments|wrote the manuscript	designed experiments	Conceived and designed the experiments	Methodology	YES
5641923	28688576	GvdB	2	designed experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5641923	28688576	ID	2	designed experiments|performed experiments|analyzed data|wrote the manuscript	designed experiments	Conceived and designed the experiments	Methodology	YES
5641923	28688576	ID	2	designed experiments|performed experiments|analyzed data|wrote the manuscript	performed experiments	Performed the experiments	Investigation	YES
5641923	28688576	ID	2	designed experiments|performed experiments|analyzed data|wrote the manuscript	analyzed data	Analyzed the data	Formal analysis	YES
5641923	28688576	ID	2	designed experiments|performed experiments|analyzed data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5641923	28688576	LP	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5641923	28688576	MtB	2	designed experiments	designed experiments	Conceived and designed the experiments	Methodology	YES
4401517	25884674	CTR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401517	25884674	CTR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401517	25884674	CTR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401517	25884674	CTR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401517	25884674	DGS	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401517	25884674	DGS	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401517	25884674	MR	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1177975	15935097	Surface Muscles	5	studied during abdominal curl up exercise Rectus Abdominis External Oblique Internal Oblique Erector Spinae Ball 29|studied during bench press exercise Rectus Abdominis External Oblique Internal Oblique Erector Spinae Ball 7|studied during biceps curl exercise Rectus Abdominis External Oblique Internal Oblique Erector Spinae Ball 5|studied during lateral raise exercise Rectus Abdominis External Oblique Internal Oblique Erector Spinae Ball 5|studied during shoulder press exercise Rectus Abdominis External Oblique Internal Oblique Erector Spinae Ball 6	studied during abdominal curl up exercise Rectus Abdominis External Oblique Internal Oblique Erector Spinae Ball 29	-	-	NO
1177975	15935097	Surface Muscles	5	studied during abdominal curl up exercise Rectus Abdominis External Oblique Internal Oblique Erector Spinae Ball 29|studied during bench press exercise Rectus Abdominis External Oblique Internal Oblique Erector Spinae Ball 7|studied during biceps curl exercise Rectus Abdominis External Oblique Internal Oblique Erector Spinae Ball 5|studied during lateral raise exercise Rectus Abdominis External Oblique Internal Oblique Erector Spinae Ball 5|studied during shoulder press exercise Rectus Abdominis External Oblique Internal Oblique Erector Spinae Ball 6	studied during bench press exercise Rectus Abdominis External Oblique Internal Oblique Erector Spinae Ball 7	-	-	NO
1177975	15935097	Surface Muscles	5	studied during abdominal curl up exercise Rectus Abdominis External Oblique Internal Oblique Erector Spinae Ball 29|studied during bench press exercise Rectus Abdominis External Oblique Internal Oblique Erector Spinae Ball 7|studied during biceps curl exercise Rectus Abdominis External Oblique Internal Oblique Erector Spinae Ball 5|studied during lateral raise exercise Rectus Abdominis External Oblique Internal Oblique Erector Spinae Ball 5|studied during shoulder press exercise Rectus Abdominis External Oblique Internal Oblique Erector Spinae Ball 6	studied during biceps curl exercise Rectus Abdominis External Oblique Internal Oblique Erector Spinae Ball 5	-	-	NO
1177975	15935097	Surface Muscles	5	studied during abdominal curl up exercise Rectus Abdominis External Oblique Internal Oblique Erector Spinae Ball 29|studied during bench press exercise Rectus Abdominis External Oblique Internal Oblique Erector Spinae Ball 7|studied during biceps curl exercise Rectus Abdominis External Oblique Internal Oblique Erector Spinae Ball 5|studied during lateral raise exercise Rectus Abdominis External Oblique Internal Oblique Erector Spinae Ball 5|studied during shoulder press exercise Rectus Abdominis External Oblique Internal Oblique Erector Spinae Ball 6	studied during lateral raise exercise Rectus Abdominis External Oblique Internal Oblique Erector Spinae Ball 5	-	-	NO
1177975	15935097	Surface Muscles	5	studied during abdominal curl up exercise Rectus Abdominis External Oblique Internal Oblique Erector Spinae Ball 29|studied during bench press exercise Rectus Abdominis External Oblique Internal Oblique Erector Spinae Ball 7|studied during biceps curl exercise Rectus Abdominis External Oblique Internal Oblique Erector Spinae Ball 5|studied during lateral raise exercise Rectus Abdominis External Oblique Internal Oblique Erector Spinae Ball 5|studied during shoulder press exercise Rectus Abdominis External Oblique Internal Oblique Erector Spinae Ball 6	studied during shoulder press exercise Rectus Abdominis External Oblique Internal Oblique Erector Spinae Ball 6	-	-	NO
4150017	25174641	CC	PLoS52	conceived and designed the study|analyzed the data|drafted the manuscript|gave comments to and revised the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4150017	25174641	CC	PLoS52	conceived and designed the study|analyzed the data|drafted the manuscript|gave comments to and revised the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
4150017	25174641	CC	PLoS52	conceived and designed the study|analyzed the data|drafted the manuscript|gave comments to and revised the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4150017	25174641	CC	PLoS52	conceived and designed the study|analyzed the data|drafted the manuscript|gave comments to and revised the manuscript	gave comments to and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4150017	25174641	PY	PLoS52	collected the data	collected the data	Performed the experiments	Investigation	YES
5474486	28674540	BH	2	participated in data analysis and supported technically	participated in data analysis and supported technically	Analyzed the data	Formal analysis	YES
5474486	28674540	KH	2	carried out the experiment	carried out the experiment	Performed the experiments	Investigation	YES
5474486	28674540	KS	2	participated in data analysis and supported technically	participated in data analysis and supported technically	Analyzed the data	Formal analysis	YES
5474486	28674540	LZ	2	participated in the research design, analyzing the data and drafting the manuscript, and initiated the project, designed the research framework, coordinated the research and reviewed the manuscript	participated in the research design, analyzing the data and drafting the manuscript, and initiated the project, designed the research framework, coordinated the research and reviewed the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Project administration|Writing - Original Draft|Writing - Review & Editing	YES
5474486	28674540	RZ	2	participated in data analysis and supported technically	participated in data analysis and supported technically	Analyzed the data	Formal analysis	YES
5474486	28674540	ZJ	2	participated in data analysis and supported technically	participated in data analysis and supported technically	Analyzed the data	Formal analysis	YES
4441995	26064884	Qin Zhou	2	contributed equally as co-first authors of this work	contributed equally as co-first authors of this work	-	-	NO
4441995	26064884	Shun Chen	2	contributed equally as co-first authors of this work	contributed equally as co-first authors of this work	-	-	NO
5101690	27829354	CYF	2	contributed to oil extraction and rna extraction	contributed to oil extraction and rna extraction	Performed the experiments	Investigation	YES
5101690	27829354	DDY	2	contributed to oil extraction and rna extraction	contributed to oil extraction and rna extraction	Performed the experiments	Investigation	YES
5101690	27829354	HJZ	2	assisted with the sample collection	assisted with the sample collection	Performed the experiments	Investigation	YES
5101690	27829354	JW	2	contributed to manuscript revision	contributed to manuscript revision	Wrote the paper	Writing - Review & Editing	YES
5101690	27829354	QW	2	carried out sequence data analysis and drafted the manuscript	carried out sequence data analysis and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5101690	27829354	RYW	2	assisted with the sample collection	assisted with the sample collection	Performed the experiments	Investigation	YES
5101690	27829354	SSL	2	organized the manuscript	organized the manuscript	-	-	NO
2712469	19545433	AG	2	was responsible for the overall conduct of the study including conception and design of the study, data acquisition, data analysis, and drafting of the manuscript	was responsible for the overall conduct of the study including conception and design of the study, data acquisition, data analysis, and drafting of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
2712469	19545433	ETG	2	participated in the study design and the critical review of the manuscript	participated in the study design and the critical review of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
2712469	19545433	LB	2	was responsible for data analysis, drafting and critical review of the manuscript	was responsible for data analysis, drafting and critical review of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
2712469	19545433	LJ	2	participated in the study design and the critical review of the manuscript	participated in the study design and the critical review of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
2712469	19545433	MR	2	participated in the data analysis and the critical review of the manuscript	participated in the data analysis and the critical review of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
2712469	19545433	NCC	2	participated in the data collection and the critical review of the manuscript	participated in the data collection and the critical review of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
2712469	19545433	SG	2	participated in the study design, data analysis, drafting and critical review of the manuscript	participated in the study design, data analysis, drafting and critical review of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
2712469	19545433	ST	2	participated in the study design and the critical review of the manuscript	participated in the study design and the critical review of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
4061145	24874559	All authors	2	have given approval to the final version of the manuscript	have given approval to the final version of the manuscript	-	-	NO
4401518	25886649	KDG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401518	25886649	KDG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401518	25886649	KDG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401518	25886649	KDG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401518	25886649	KDG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401518	25886649	SLR	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5474487	28674550	FC	2	discussed the results and commented on the manuscript, and all the authors approved the final version of the article	discussed the results and commented on the manuscript, and all the authors approved the final version of the article	-	-	NO
5474487	28674550	GE	2	initiated the experiment and performed all the experimental measurements|wrote the manuscript	initiated the experiment and performed all the experimental measurements	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5474487	28674550	GE	2	initiated the experiment and performed all the experimental measurements|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5474487	28674550	GQ	2	initiated the experiment and performed all the experimental measurements|wrote the manuscript	initiated the experiment and performed all the experimental measurements	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5474487	28674550	GQ	2	initiated the experiment and performed all the experimental measurements|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5474487	28674550	JR-L	2	designed the experiment and analyzed all the results|wrote the manuscript	designed the experiment and analyzed all the results	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5474487	28674550	JR-L	2	designed the experiment and analyzed all the results|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5474487	28674550	RA	2	discussed the results and commented on the manuscript, and all the authors approved the final version of the article	discussed the results and commented on the manuscript, and all the authors approved the final version of the article	-	-	NO
1282585	16255773	RKJ	2	participated in the design of the study|participated in its design and coordination and helped to draft the manuscript	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
1282585	16255773	RKJ	2	participated in the design of the study|participated in its design and coordination and helped to draft the manuscript	participated in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Project administration|Writing - Original Draft	YES
1282585	16255773	VLC	2	carried out the data collection and data analysis	carried out the data collection and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4154142	25186918	ADC	1	Concept and design|Analysis|Manuscript	Concept and design	Conceived and designed the experiments	Conceptualization	YES
4154142	25186918	ADC	1	Concept and design|Analysis|Manuscript	Analysis	-	-	NO
4154142	25186918	ADC	1	Concept and design|Analysis|Manuscript	Manuscript	-	-	NO
4154142	25186918	AS	1	Concept and design|Data collection|Critical review	Concept and design	Conceived and designed the experiments	Conceptualization	YES
4154142	25186918	AS	1	Concept and design|Data collection|Critical review	Data collection	Performed the experiments	Investigation	YES
4154142	25186918	AS	1	Concept and design|Data collection|Critical review	Critical review	-	-	NO
4154142	25186918	LB	1	Concept and design|Analysis|Manuscript	Concept and design	Conceived and designed the experiments	Conceptualization	YES
4154142	25186918	LB	1	Concept and design|Analysis|Manuscript	Analysis	-	-	NO
4154142	25186918	LB	1	Concept and design|Analysis|Manuscript	Manuscript	-	-	NO
4154142	25186918	RR	1	Concept and design|Data collection|Analysis|Manuscript	Concept and design	Conceived and designed the experiments	Conceptualization	YES
4154142	25186918	RR	1	Concept and design|Data collection|Analysis|Manuscript	Data collection	Performed the experiments	Investigation	YES
4154142	25186918	RR	1	Concept and design|Data collection|Analysis|Manuscript	Analysis	-	-	NO
4154142	25186918	RR	1	Concept and design|Data collection|Analysis|Manuscript	Manuscript	-	-	NO
4154142	25186918	SK	1	Concept and design|Critical review	Concept and design	Conceived and designed the experiments	Conceptualization	YES
4154142	25186918	SK	1	Concept and design|Critical review	Critical review	-	-	NO
5101730	27825295	CL	2	analyzed the data and drafted the manuscript	analyzed the data and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5101730	27825295	ESB	2	conceived of the study, managed the project design and coordination, collected data, and helped to draft the manuscript	conceived of the study, managed the project design and coordination, collected data, and helped to draft the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Data curation|Investigation|Methodology|Project administration|Writing - Original Draft	YES
5101730	27825295	LC	2	provided phenotypic information	provided phenotypic information	Performed the experiments	Investigation	YES
5101730	27825295	SB	2	provided phenotypic information	provided phenotypic information	Performed the experiments	Investigation	YES
5101730	27825295	SY	2	participated in the data collection|participated in the data collection	participated in the data collection	Performed the experiments	Investigation	YES
5101730	27825295	SY	2	participated in the data collection|participated in the data collection	participated in the data collection	Performed the experiments	Investigation	YES
5101730	27825295	TW	2	conceived of the study, managed the project design and coordination, collected data, and helped to draft the manuscript	conceived of the study, managed the project design and coordination, collected data, and helped to draft the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Data curation|Investigation|Methodology|Project administration|Writing - Original Draft	YES
5101730	27825295	XW	2	participated in the data collection	participated in the data collection	Performed the experiments	Investigation	YES
5101730	27825295	YL	2	participated in the study design and analyzed the data|conceived of the study, managed the project design and coordination, collected data, and helped to draft the manuscript	participated in the study design and analyzed the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5101730	27825295	YL	2	participated in the study design and analyzed the data|conceived of the study, managed the project design and coordination, collected data, and helped to draft the manuscript	conceived of the study, managed the project design and coordination, collected data, and helped to draft the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Data curation|Investigation|Methodology|Project administration|Writing - Original Draft	YES
5101730	27825295	ZD	2	participated in the data collection	participated in the data collection	Performed the experiments	Investigation	YES
5101730	27825295	ZZ	2	conceived of the study, managed the project design and coordination, collected data, and helped to draft the manuscript	conceived of the study, managed the project design and coordination, collected data, and helped to draft the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Data curation|Investigation|Methodology|Project administration|Writing - Original Draft	YES
4744950	25995119	All authors	2	contributed equally to the development and design of the algorithm	contributed equally to the development and design of the algorithm	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
4744950	25995119	Dr Grant	2	were lead authors in drafting the submitted manuscript, to which all authors contributed	were lead authors in drafting the submitted manuscript, to which all authors contributed	Wrote the paper	Writing - Original Draft	YES
4744950	25995119	Professor Grossman	2	were lead authors in drafting the submitted manuscript, to which all authors contributed	were lead authors in drafting the submitted manuscript, to which all authors contributed	Wrote the paper	Writing - Original Draft	YES
2713257	19570221	ACK	2	also contributed to the design and data analyses of the study	also contributed to the design and data analyses of the study	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Methodology|Resources	YES
2713257	19570221	AE	2	also contributed to the design and data analyses of the study	also contributed to the design and data analyses of the study	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Methodology|Resources	YES
2713257	19570221	AL	2	performed the purification and quantification of memory cells and the cytokine analyses under the|also contributed to the design and data analyses of the study	performed the purification and quantification of memory cells and the cytokine analyses under the	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
2713257	19570221	AL	2	performed the purification and quantification of memory cells and the cytokine analyses under the|also contributed to the design and data analyses of the study	also contributed to the design and data analyses of the study	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Methodology|Resources	YES
2713257	19570221	AS	2	supervised the performed the purification and quantification of memory cells and the cytokine analyses under the|also contributed to the design and data analyses of the study	supervised the performed the purification and quantification of memory cells and the cytokine analyses under the	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Supervision	YES
2713257	19570221	AS	2	supervised the performed the purification and quantification of memory cells and the cytokine analyses under the|also contributed to the design and data analyses of the study	also contributed to the design and data analyses of the study	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Methodology|Resources	YES
2713257	19570221	All of the authors	2	contributed to the manuscript preparation and all have seen and approved the final version	contributed to the manuscript preparation and all have seen and approved the final version	Wrote the paper	Writing - Original Draft	YES
2713257	19570221	JKS	2	also contributed to the design and data analyses of the study	also contributed to the design and data analyses of the study	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Methodology|Resources	YES
2713257	19570221	MG	2	originated the idea, designed the study, recruited the participants, performed data analyses, and wrote the article	originated the idea, designed the study, recruited the participants, performed data analyses, and wrote the article	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
2713257	19570221	SN	2	handled the statistics	handled the statistics	Analyzed the data	Formal analysis	YES
2713257	19570221	VDG	2	conducted the t-cell analyses	conducted the t-cell analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4232737	25151399	J.W.	PLoS52	designed the experiments|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
4232737	25151399	J.W.	PLoS52	designed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4232737	25151399	R.P.	PLoS52	developed the matlab program for nuclear counting	developed the matlab program for nuclear counting	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
4232737	25151399	R.S.	PLoS52	designed the experiments|performed the experiments|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
4232737	25151399	R.S.	PLoS52	designed the experiments|performed the experiments|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
4232737	25151399	R.S.	PLoS52	designed the experiments|performed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4232737	25151399	S.H.	PLoS52	designed the experiments|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
4232737	25151399	S.H.	PLoS52	designed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4156595	25192857	AS	2	performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
4156595	25192857	All Authors	2	contributed to the concept, design of the study and the interpretation of the results	contributed to the concept, design of the study and the interpretation of the results	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
4156595	25192857	All authors	2	have reviewed and approved the final manuscript	have reviewed and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4401520	25886466	SY	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401520	25886466	XL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401520	25886466	XL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401520	25886466	XL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401520	25886466	XL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401520	25886466	XL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401520	25886466	XS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401520	25886466	YZ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401520	25886466	YZ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401520	25886466	YZ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401520	25886466	Yongping Yang	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401520	25886466	Yongping Yang	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401520	25886466	Yunqiang Yang	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5474488	28674549	All the authors	PLoS52	have read and approved the publication of the manuscript	have read and approved the publication of the manuscript	-	-	NO
5474488	28674549	BC	PLoS52	organized the implementation of field trials	organized the implementation of field trials	Performed the experiments	Investigation|Project administration	YES
5474488	28674549	FZ	PLoS52	performed the phenotyping measurements	performed the phenotyping measurements	Performed the experiments	Investigation	YES
5474488	28674549	GG	PLoS52	organized the implementation of field trials	organized the implementation of field trials	Performed the experiments	Investigation|Project administration	YES
5474488	28674549	HL	PLoS52	conceived and designed the study|performed the phenotyping measurements|wrote the paper	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5474488	28674549	HL	PLoS52	conceived and designed the study|performed the phenotyping measurements|wrote the paper	performed the phenotyping measurements	Performed the experiments	Investigation	YES
5474488	28674549	HL	PLoS52	conceived and designed the study|performed the phenotyping measurements|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5474488	28674549	JH	PLoS52	modified the manuscript	modified the manuscript	Wrote the paper	Writing - Review & Editing	YES
5474488	28674549	KX	PLoS52	organized the implementation of field trials	organized the implementation of field trials	Performed the experiments	Investigation|Project administration	YES
5474488	28674549	LZ	PLoS52	performed the phenotyping measurements	performed the phenotyping measurements	Performed the experiments	Investigation	YES
5474488	28674549	TZ	PLoS52	performed the phenotyping measurements	performed the phenotyping measurements	Performed the experiments	Investigation	YES
5474488	28674549	XW	PLoS52	conceived and designed the study|modified the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5474488	28674549	XW	PLoS52	conceived and designed the study|modified the manuscript	modified the manuscript	Wrote the paper	Writing - Review & Editing	YES
5474488	28674549	ZL	PLoS52	conceived and designed the study|modified the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5474488	28674549	ZL	PLoS52	conceived and designed the study|modified the manuscript	modified the manuscript	Wrote the paper	Writing - Review & Editing	YES
4159947	25204873	CB	2	all contributed to the preparation of the manuscript	all contributed to the preparation of the manuscript	Wrote the paper	Writing - Original Draft	YES
4159947	25204873	DAC	2	all contributed to the preparation of the manuscript	all contributed to the preparation of the manuscript	Wrote the paper	Writing - Original Draft	YES
4159947	25204873	SV	2	all contributed to the preparation of the manuscript	all contributed to the preparation of the manuscript	Wrote the paper	Writing - Original Draft	YES
2717984	19563676	AMS	2	provided overall direction and had primary responsibility for writing and finalizing the manuscript, which all authors have read and approved	provided overall direction and had primary responsibility for writing and finalizing the manuscript, which all authors have read and approved	Wrote the paper	Supervision|Writing - Original Draft|Writing - Review & Editing	YES
2717984	19563676	GM	2	conducted all of the optimization studies and performed all of the assays and some of the calculations included in the manuscript	conducted all of the optimization studies and performed all of the assays and some of the calculations included in the manuscript	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
2717984	19563676	JC	2	designed the assay and performed some of the preliminary experiments	designed the assay and performed some of the preliminary experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
2717984	19563676	MDA	2	supervised the work and data analysis, and contributed to writing and editing the manuscript	supervised the work and data analysis, and contributed to writing and editing the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
2717984	19563676	XZZ	2	synthesized and tested the hiv-1 inhibitors under the supervision of trb	synthesized and tested the hiv-1 inhibitors under the supervision of trb	Performed the experiments	Investigation|Supervision	YES
4401536	25884983	CC	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4401536	25884983	CC	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401536	25884983	CL	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4401536	25884983	CL	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401536	25884983	HD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401536	25884983	HD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4401536	25884983	HD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401536	25884983	MZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401536	25884983	MZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401536	25884983	MZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401536	25884983	MZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401536	25884983	SC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401536	25884983	SC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401536	25884983	SC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401536	25884983	XM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401536	25884983	XM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401536	25884983	XM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401536	25884983	XM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401536	25884983	YX	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401536	25884983	YX	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401536	25884983	YX	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5101800	27825301	RP	2	conceived and designed the study|wrote the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5101800	27825301	RP	2	conceived and designed the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5101800	27825301	YH	2	conceived and designed the study|performed the analysis|wrote the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5101800	27825301	YH	2	conceived and designed the study|performed the analysis|wrote the manuscript	performed the analysis	Performed the experiments	Investigation	YES
5101800	27825301	YH	2	conceived and designed the study|performed the analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4442013	26064912	Jingqi Chen	2	helped with the data analysis|helped in revising the paper	helped with the data analysis	Analyzed the data	Formal analysis	YES
4442013	26064912	Jingqi Chen	2	helped with the data analysis|helped in revising the paper	helped in revising the paper	Wrote the paper	Writing - Review & Editing	YES
4442013	26064912	Qi Ni	2	conducted the data analysis and drafted the paper|contributed equally to the work	conducted the data analysis and drafted the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4442013	26064912	Qi Ni	2	conducted the data analysis and drafted the paper|contributed equally to the work	contributed equally to the work	-	-	NO
4442013	26064912	Weidong Tian	2	conceived the idea|helped in revising the paper	conceived the idea	Conceived and designed the experiments	Conceptualization	YES
4442013	26064912	Weidong Tian	2	conceived the idea|helped in revising the paper	helped in revising the paper	Wrote the paper	Writing - Review & Editing	YES
4442013	26064912	Xianming Su	2	conducted the data analysis and drafted the paper|contributed equally to the work	conducted the data analysis and drafted the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4442013	26064912	Xianming Su	2	conducted the data analysis and drafted the paper|contributed equally to the work	contributed equally to the work	-	-	NO
4159948	25204872	JP	2	was the sole author for the manuscript	was the sole author for the manuscript	-	-	NO
2723132	19607684	AVR	2	conceived of the study and participated in its design and coordination and helped draft the manuscript	conceived of the study and participated in its design and coordination and helped draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
2723132	19607684	CF	2	conceived of the study and participated in its design and coordination and helped draft the manuscript	conceived of the study and participated in its design and coordination and helped draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
2723132	19607684	DG	2	supervised laboratory efforts, provided technical laboratory expertise, and contributed to manuscript writing	supervised laboratory efforts, provided technical laboratory expertise, and contributed to manuscript writing	Wrote the paper	Supervision|Writing - Original Draft	YES
2723132	19607684	DM	2	carried out the flow cytometry studies and drafted the manuscript|conceived of the study and participated in its design and coordination and helped draft the manuscript	carried out the flow cytometry studies and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
2723132	19607684	DM	2	carried out the flow cytometry studies and drafted the manuscript|conceived of the study and participated in its design and coordination and helped draft the manuscript	conceived of the study and participated in its design and coordination and helped draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
2723132	19607684	JO	2	supervised laboratory efforts, provided technical laboratory expertise, and contributed to manuscript writing	supervised laboratory efforts, provided technical laboratory expertise, and contributed to manuscript writing	Wrote the paper	Supervision|Writing - Original Draft	YES
2723132	19607684	KW	2	supervised laboratory efforts, provided technical laboratory expertise, and contributed to manuscript writing	supervised laboratory efforts, provided technical laboratory expertise, and contributed to manuscript writing	Wrote the paper	Supervision|Writing - Original Draft	YES
2723132	19607684	MS	2	carried out the flow cytometry studies and drafted the manuscript	carried out the flow cytometry studies and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
2723132	19607684	PM	2	coordinated laboratory investigations	coordinated laboratory investigations	Performed the experiments	Investigation|Project administration	YES
2723132	19607684	WDFV	2	conceived of the study and participated in its design and coordination and helped draft the manuscript	conceived of the study and participated in its design and coordination and helped draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
2723132	19607684	WS	2	supervised laboratory efforts, provided technical laboratory expertise, and contributed to manuscript writing	supervised laboratory efforts, provided technical laboratory expertise, and contributed to manuscript writing	Wrote the paper	Supervision|Writing - Original Draft	YES
5111733	27002914	ADP	2	interpreted the data	interpreted the data	Analyzed the data	Formal analysis	YES
5111733	27002914	All authors	2	intellectually contributed to the manuscript, helped drafting the manuscript and have read and approved the final version	intellectually contributed to the manuscript, helped drafting the manuscript and have read and approved the final version	Wrote the paper	Writing - Original Draft	YES
5111733	27002914	BHRW	2	conceived and designed the study|performed the statistical analysis and analysed the data|interpreted the data	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5111733	27002914	BHRW	2	conceived and designed the study|performed the statistical analysis and analysed the data|interpreted the data	performed the statistical analysis and analysed the data	Analyzed the data	Formal analysis	YES
5111733	27002914	BHRW	2	conceived and designed the study|performed the statistical analysis and analysed the data|interpreted the data	interpreted the data	Analyzed the data	Formal analysis	YES
5111733	27002914	HLL	2	interpreted the data	interpreted the data	Analyzed the data	Formal analysis	YES
5111733	27002914	JVO	2	interpreted the data	interpreted the data	Analyzed the data	Formal analysis	YES
5111733	27002914	MMvdK	2	conceived and designed the study|interpreted the data	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5111733	27002914	MMvdK	2	conceived and designed the study|interpreted the data	interpreted the data	Analyzed the data	Formal analysis	YES
5111733	27002914	RG	2	interpreted the data	interpreted the data	Analyzed the data	Formal analysis	YES
5111733	27002914	RPW	2	conceived and designed the study|performed the statistical analysis and analysed the data|interpreted the data|drafted the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5111733	27002914	RPW	2	conceived and designed the study|performed the statistical analysis and analysed the data|interpreted the data|drafted the manuscript	performed the statistical analysis and analysed the data	Analyzed the data	Formal analysis	YES
5111733	27002914	RPW	2	conceived and designed the study|performed the statistical analysis and analysed the data|interpreted the data|drafted the manuscript	interpreted the data	Analyzed the data	Formal analysis	YES
5111733	27002914	RPW	2	conceived and designed the study|performed the statistical analysis and analysed the data|interpreted the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5111733	27002914	SNS	2	interpreted the data	interpreted the data	Analyzed the data	Formal analysis	YES
5474491	28674542	EE	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5474491	28674542	EE	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5474491	28674542	QZ	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5474491	28674542	QZ	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5474491	28674542	WW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5474491	28674542	WW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
5474491	28674542	WW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5474491	28674542	WW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5474491	28674542	XZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5474491	28674542	XZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
5474491	28674542	XZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5474491	28674542	XZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5474491	28674542	ZY	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1456951	16597328	AAA	7	executed study design and contributed to the manuscript	executed study design and contributed to the manuscript	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
1456951	16597328	DAD	7	coordinated and executed study design and contributed to the manuscript	coordinated and executed study design and contributed to the manuscript	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Project administration	YES
1456951	16597328	JDA	7	executed study design, and contributed to the manuscript	executed study design, and contributed to the manuscript	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
1456951	16597328	MAW	7	conceived of study design and contributed to the manuscript	conceived of study design and contributed to the manuscript	Conceived and designed the experiments	Conceptualization|Methodology	YES
1456951	16597328	RHW	7	offered critique of final manuscript	offered critique of final manuscript	Wrote the paper	Writing - Review & Editing	YES
4442020	26090415	Qizhi Luo	2	contributed equally to this work	contributed equally to this work	-	-	NO
4442020	26090415	Wei Li	2	contributed equally to this work	contributed equally to this work	-	-	NO
5474533	28674551	All authors	2	read and approved the manuscript	read and approved the manuscript	-	-	NO
5474533	28674551	TW	2	prepared the plant materials and designed the experiments	prepared the plant materials and designed the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5474533	28674551	XH	2	conducted the experiments	conducted the experiments	Performed the experiments	Investigation	YES
5474533	28674551	XL	2	conducted the experiments	conducted the experiments	Performed the experiments	Investigation	YES
5474533	28674551	XZ	2	prepared the plant materials and designed the experiments	prepared the plant materials and designed the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5474533	28674551	XzX	2	prepared the plant materials and designed the experiments|conducted the experiments|took the photographs|wrote the manuscript	prepared the plant materials and designed the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5474533	28674551	XzX	2	prepared the plant materials and designed the experiments|conducted the experiments|took the photographs|wrote the manuscript	conducted the experiments	Performed the experiments	Investigation	YES
5474533	28674551	XzX	2	prepared the plant materials and designed the experiments|conducted the experiments|took the photographs|wrote the manuscript	took the photographs	-	Visualization	YES
5474533	28674551	XzX	2	prepared the plant materials and designed the experiments|conducted the experiments|took the photographs|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5474533	28674551	YW	2	prepared the plant materials and designed the experiments	prepared the plant materials and designed the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5474533	28674551	ZH	2	prepared the plant materials and designed the experiments	prepared the plant materials and designed the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
2731026	19630949	BKK	7	Study concept and design, data analysis, interpretation of the study findings and wrote-up the manuscript	Study concept and design, data analysis, interpretation of the study findings and wrote-up the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
2731026	19630949	BN	7	Assisted in the interpretation of study findings and the critical revision the manuscript	Assisted in the interpretation of study findings and the critical revision the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
2731026	19630949	CK	7	Assisted in the interpretation of study findings and the critical revision the manuscript	Assisted in the interpretation of study findings and the critical revision the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
2731026	19630949	EK	7	Assisted in the interpretation of study findings and the critical revision the manuscript	Assisted in the interpretation of study findings and the critical revision the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
2731026	19630949	FS	7	Assisted in the study concept and design, interpretation of the study findings and the critical revision of the manuscript	Assisted in the study concept and design, interpretation of the study findings and the critical revision of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Review & Editing	YES
2731026	19630949	JK	7	assisted in data analysis, interpretation of study findings and the critical revision of the final manuscript	assisted in data analysis, interpretation of study findings and the critical revision of the final manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
2731026	19630949	MO	7	Queried and extracted data from jcrc database	Queried and extracted data from jcrc database	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
2731026	19630949	MP	7	Assisted in the interpretation of study findings and the critical revision the manuscript	Assisted in the interpretation of study findings and the critical revision the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
2731026	19630949	PM	7	assisted in critical revision and the final approval of manuscript	assisted in critical revision and the final approval of manuscript	Wrote the paper	Writing - Review & Editing	YES
2731026	19630949	SS	7	Assisted in the interpretation of study findings and the critical revision the manuscript	Assisted in the interpretation of study findings and the critical revision the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4161962	25216073	FLA	1	Conceived and designed the study	Conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4161962	25216073	JAW	1	Conceived and designed the study	Conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4161962	25216073	LA	1	Conceived and designed the study	Conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4161962	25216073	SD	1	Conceived and designed the study	Conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4161962	25216073	YG	1	Conceived and designed the study	Conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
1489922	16734915	All authors	2	contributed equally to this research study	contributed equally to this research study	-	-	NO
1489922	16734915	MM	2	was a graduate student that collected and analyzed the physiological data	was a graduate student that collected and analyzed the physiological data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
1489922	16734915	PN	2	assisted in the research design, analysis and interpretation of the near infrared spectroscopy data, and edited and approved the final manuscript	assisted in the research design, analysis and interpretation of the near infrared spectroscopy data, and edited and approved the final manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
4401539	25886253	BAC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401539	25886253	BAC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401539	25886253	BAC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401539	25886253	BAC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401539	25886253	CDD	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401539	25886253	CDD	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401539	25886253	DLH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401539	25886253	DLH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401539	25886253	DLH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401539	25886253	DLH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401539	25886253	EA	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4401539	25886253	EA	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401539	25886253	HES	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401539	25886253	MHY	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401539	25886253	PAT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401539	25886253	PAT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401539	25886253	PAT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401539	25886253	PAT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401539	25886253	PAT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401539	25886253	SNS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401539	25886253	VNG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401539	25886253	VNG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401539	25886253	VNG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401539	25886253	WCR	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4401539	25886253	WCR	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401539	25886253	XMX	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401539	25886253	YH	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4401539	25886253	YH	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5101819	27825300	CSJ	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5101819	27825300	HY	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5101819	27825300	WB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
5101819	27825300	WB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5101819	27825300	WB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5101819	27825300	WB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5101819	27825300	WXT	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5101819	27825300	YE	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
5101819	27825300	YE	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
5101819	27825300	YE	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5101819	27825300	YN	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5101819	27825300	YQG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5101819	27825300	YQG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4442255	26078972	Cristian Levente Giuroiu	2	have equal contributions	have equal contributions	-	-	NO
4442255	26078972	Irina-Draga Caruntu	2	have equal contributions	have equal contributions	-	-	NO
4269404	25380349	H.W.	2	contributed equally to this work	contributed equally to this work	-	-	NO
4269404	25380349	J.G.	2	contributed equally to this work	contributed equally to this work	-	-	NO
2731786	19660105	AP	2	reviewed the study findings from a clinical standpoint and helped draft the manuscript	reviewed the study findings from a clinical standpoint and helped draft the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
2731786	19660105	DT	2	reviewed the study findings from a toxicological standpoint and helped draft the manuscript	reviewed the study findings from a toxicological standpoint and helped draft the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
2731786	19660105	JKJ	2	conceived of the study, and participated in its design and coordination and helped draft the manuscript	conceived of the study, and participated in its design and coordination and helped draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
2731786	19660105	LM	2	conceived of the study, and participated in its design and coordination and helped draft the manuscript	conceived of the study, and participated in its design and coordination and helped draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
2731786	19660105	MS	2	conceived of the study, and participated in its design and coordination and helped draft the manuscript	conceived of the study, and participated in its design and coordination and helped draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
2731786	19660105	PL	2	conceived of the study, and participated in its design and coordination and helped draft the manuscript	conceived of the study, and participated in its design and coordination and helped draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
5474874	28674546	All authors	2	reviewed the results and approved the final version of the manuscript	reviewed the results and approved the final version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5474874	28674546	D-LW	2	performed and analyzed the experiments	performed and analyzed the experiments	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5474874	28674546	EC	2	provided technical assistance and analysis and interpretation of data	provided technical assistance and analysis and interpretation of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5474874	28674546	HY	2	performed and analyzed the experiments	performed and analyzed the experiments	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5474874	28674546	JD	2	performed and analyzed the experiments	performed and analyzed the experiments	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5474874	28674546	JL	2	performed and analyzed the experiments	performed and analyzed the experiments	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5474874	28674546	JY	2	performed and analyzed the experiments	performed and analyzed the experiments	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5474874	28674546	KH	2	provided technical assistance and analysis and interpretation of data	provided technical assistance and analysis and interpretation of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5474874	28674546	MG	2	designed the study and wrote the paper	designed the study and wrote the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5474874	28674546	NC	2	designed the study and wrote the paper|performed and analyzed the experiments	designed the study and wrote the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5474874	28674546	NC	2	designed the study and wrote the paper|performed and analyzed the experiments	performed and analyzed the experiments	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5474874	28674546	PN	2	provided technical assistance and analysis and interpretation of data	provided technical assistance and analysis and interpretation of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5474874	28674546	SP	2	performed and analyzed the experiments	performed and analyzed the experiments	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5474874	28674546	ST	2	performed and analyzed the experiments	performed and analyzed the experiments	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5474874	28674546	TR	2	performed and analyzed the experiments	performed and analyzed the experiments	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5474874	28674546	YS	2	performed and analyzed the experiments	performed and analyzed the experiments	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3614819	23675215	DCG	2	contributed to the protocol development, laboratory animal management and analytical framework	contributed to the protocol development, laboratory animal management and analytical framework	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3614819	23675215	HJO	2	had primary responsibility for protocol development, animals screening, outcome assessment and development of lab methods	had primary responsibility for protocol development, animals screening, outcome assessment and development of lab methods	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3614819	23675215	JFH	2	supervised the design and execution of the study, performed the final data analysis and contributed to the writing of the manuscript	supervised the design and execution of the study, performed the final data analysis and contributed to the writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Supervision|Writing - Original Draft	YES
3614819	23675215	RAM	2	contributed to the protocol development, laboratory animal management and analytical framework	contributed to the protocol development, laboratory animal management and analytical framework	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
1508143	16762080	EMG	2	during three push ups with the hands on an exercise bench or a swiss ball for the triceps and pectoralis major muscle|on ball	during three push ups with the hands on an exercise bench or a swiss ball for the triceps and pectoralis major muscle	-	-	NO
1508143	16762080	EMG	2	during three push ups with the hands on an exercise bench or a swiss ball for the triceps and pectoralis major muscle|on ball	on ball	-	-	NO
1508143	16762080	Pectoralis Major	2	on ball	on ball	-	-	NO
4163992	25224619	AK	2	provided additional methodologies and specific examples as well as expert review	provided additional methodologies and specific examples as well as expert review	Performed the experiments	Methodology	YES
4163992	25224619	AL	2	developed the conceptual framework for this commentary on user research approaches, including identifying key themes and methodologies to include	developed the conceptual framework for this commentary on user research approaches, including identifying key themes and methodologies to include	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
4163992	25224619	CV	2	provided additional methodologies and specific examples as well as expert review	provided additional methodologies and specific examples as well as expert review	Performed the experiments	Methodology	YES
4163992	25224619	EH	2	developed the conceptual framework for this commentary on user research approaches, including identifying key themes and methodologies to include	developed the conceptual framework for this commentary on user research approaches, including identifying key themes and methodologies to include	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
4163992	25224619	MB	2	developed the conceptual framework for this commentary on user research approaches, including identifying key themes and methodologies to include	developed the conceptual framework for this commentary on user research approaches, including identifying key themes and methodologies to include	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
5113689	27208892	All authors	2	reviewed and edited the paper	reviewed and edited the paper	Wrote the paper	Writing - Review & Editing	YES
5113689	27208892	BD	2	participated in the analyses	participated in the analyses	Analyzed the data	Formal analysis	YES
5113689	27208892	CC	2	participated in the analyses	participated in the analyses	Analyzed the data	Formal analysis	YES
5113689	27208892	CRP	2	contributed to the design of the work|participated in the analyses	contributed to the design of the work	Conceived and designed the experiments	-	YES
5113689	27208892	CRP	2	contributed to the design of the work|participated in the analyses	participated in the analyses	Analyzed the data	Formal analysis	YES
5113689	27208892	EJGS	2	contributed to the design of the work|participated in the analyses	contributed to the design of the work	Conceived and designed the experiments	-	YES
5113689	27208892	EJGS	2	contributed to the design of the work|participated in the analyses	participated in the analyses	Analyzed the data	Formal analysis	YES
5113689	27208892	JB	2	lipoprotein profiles including apolipoprotein measurements|performed blood sampling	lipoprotein profiles including apolipoprotein measurements	Performed the experiments	Investigation	YES
5113689	27208892	JB	2	lipoprotein profiles including apolipoprotein measurements|performed blood sampling	performed blood sampling	Performed the experiments	Investigation	YES
5113689	27208892	JBvdN	2	approached potential participants and got informed consent|contributed to the design of the work|participated in the analyses	approached potential participants and got informed consent	-	-	NO
5113689	27208892	JBvdN	2	approached potential participants and got informed consent|contributed to the design of the work|participated in the analyses	contributed to the design of the work	Conceived and designed the experiments	-	YES
5113689	27208892	JBvdN	2	approached potential participants and got informed consent|contributed to the design of the work|participated in the analyses	participated in the analyses	Analyzed the data	Formal analysis	YES
5113689	27208892	JPK	2	contributed to the design of the work|participated in the analyses	contributed to the design of the work	Conceived and designed the experiments	-	YES
5113689	27208892	JPK	2	contributed to the design of the work|participated in the analyses	participated in the analyses	Analyzed the data	Formal analysis	YES
5113689	27208892	JV	2	contributed to the design of the work, performed part of the experiments and wrote the manuscript|approached potential participants and got informed consent|performed blood sampling|participated in the analyses	contributed to the design of the work, performed part of the experiments and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5113689	27208892	JV	2	contributed to the design of the work, performed part of the experiments and wrote the manuscript|approached potential participants and got informed consent|performed blood sampling|participated in the analyses	approached potential participants and got informed consent	-	-	NO
5113689	27208892	JV	2	contributed to the design of the work, performed part of the experiments and wrote the manuscript|approached potential participants and got informed consent|performed blood sampling|participated in the analyses	performed blood sampling	Performed the experiments	Investigation	YES
5113689	27208892	JV	2	contributed to the design of the work, performed part of the experiments and wrote the manuscript|approached potential participants and got informed consent|performed blood sampling|participated in the analyses	participated in the analyses	Analyzed the data	Formal analysis	YES
5113689	27208892	LvV	2	lipoprotein profiles including apolipoprotein measurements	lipoprotein profiles including apolipoprotein measurements	Performed the experiments	Investigation	YES
5113689	27208892	MM	2	contributed to the design of the work|participated in the analyses	contributed to the design of the work	Conceived and designed the experiments	-	YES
5113689	27208892	MM	2	contributed to the design of the work|participated in the analyses	participated in the analyses	Analyzed the data	Formal analysis	YES
5113689	27208892	RV	2	participated in the analyses	participated in the analyses	Analyzed the data	Formal analysis	YES
5113689	27208892	RY	2	participated in the analyses	participated in the analyses	Analyzed the data	Formal analysis	YES
4401540	25884982	JF	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401540	25884982	JF	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401540	25884982	JL	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401540	25884982	JL	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401540	25884982	NF	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401540	25884982	QM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401540	25884982	QM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401540	25884982	QM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401540	25884982	XR	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401540	25884982	XR	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401540	25884982	XR	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401540	25884982	YG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401540	25884982	YG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401540	25884982	YG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401540	25884982	YG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401540	25884982	YG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2736972	19698111	AF	2	was responsible for the collection and assembly of data, and drafting of the article	was responsible for the collection and assembly of data, and drafting of the article	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
2736972	19698111	CSY	2	was responsible for the study design, collection and assembly of data, analysis and interpretation of the data, drafting of the article, critical revision of the article, final approval of the article, and obtaining of funding	was responsible for the study design, collection and assembly of data, analysis and interpretation of the data, drafting of the article, critical revision of the article, final approval of the article, and obtaining of funding	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Funding acquisition|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
2736972	19698111	CZW	2	was responsible for the study design, collection and assembly of data, analysis and interpretation of the data, critical revision of the article, and final approval of the article	was responsible for the study design, collection and assembly of data, analysis and interpretation of the data, critical revision of the article, and final approval of the article	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Review & Editing	YES
2736972	19698111	HHA	2	was responsible for the collection and assembly of data, and analysis and interpretation of the data	was responsible for the collection and assembly of data, and analysis and interpretation of the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
2736972	19698111	RJI	2	was responsible for the study design, critical revision of the article, and final approval of the article	was responsible for the study design, critical revision of the article, and final approval of the article	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
2736972	19698111	SRM	2	was responsible for the analysis and interpretation of the data, and critical revision of the article	was responsible for the analysis and interpretation of the data, and critical revision of the article	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
1524724	16817964	BTE	2	participated in acquisition of data and coordination of the study	participated in acquisition of data and coordination of the study	Performed the experiments	Investigation|Project administration	YES
1524724	16817964	CAB	2	participated in the design of the study, interpretation of the results, and preparation of the manuscript	participated in the design of the study, interpretation of the results, and preparation of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
1524724	16817964	DEW	2	participated in coordination of the study, provided the equipment used in the study and provided important revisions to the manuscript	participated in coordination of the study, provided the equipment used in the study and provided important revisions to the manuscript	Contributed reagents/materials/analysis tools|Wrote the paper	Project administration|Resources|Writing - Review & Editing	YES
1524724	16817964	JMS	2	participated in acquisition of data and helped organize the study	participated in acquisition of data and helped organize the study	Performed the experiments	Investigation|Project administration	YES
1524724	16817964	MDK	2	designed the study, coordinated the study, acquired the data, performed the statistical analysis, and drafted the manuscript	designed the study, coordinated the study, acquired the data, performed the statistical analysis, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Project administration|Writing - Original Draft	YES
1524724	16817964	MJH	2	participated in the design of the study, interpretation of the results, and preparation of the manuscript	participated in the design of the study, interpretation of the results, and preparation of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5103334	27832764	DJ	PLoS52	conceived of the study|wrote, edited and approved the manuscript	conceived of the study	Conceived and designed the experiments	Conceptualization	YES
5103334	27832764	DJ	PLoS52	conceived of the study|wrote, edited and approved the manuscript	wrote, edited and approved the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5103334	27832764	ECT	PLoS52	conceived of the study|wrote, edited and approved the manuscript	conceived of the study	Conceived and designed the experiments	Conceptualization	YES
5103334	27832764	ECT	PLoS52	conceived of the study|wrote, edited and approved the manuscript	wrote, edited and approved the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5103334	27832764	ZH	PLoS52	conceived of the study|analyzed the data|wrote, edited and approved the manuscript	conceived of the study	Conceived and designed the experiments	Conceptualization	YES
5103334	27832764	ZH	PLoS52	conceived of the study|analyzed the data|wrote, edited and approved the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5103334	27832764	ZH	PLoS52	conceived of the study|analyzed the data|wrote, edited and approved the manuscript	wrote, edited and approved the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5474932	28674547	D-KL	2	conducted metabolome analysis|conducted analysis of integrated bioinformatics data	conducted metabolome analysis	Performed the experiments	Investigation	YES
5474932	28674547	D-KL	2	conducted metabolome analysis|conducted analysis of integrated bioinformatics data	conducted analysis of integrated bioinformatics data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5474932	28674547	H-SP	2	conducted adventitious root culture and transcriptome analysis|conducted analysis of integrated bioinformatics data|wrote and revised the manuscript	conducted adventitious root culture and transcriptome analysis	Performed the experiments	Investigation	YES
5474932	28674547	H-SP	2	conducted adventitious root culture and transcriptome analysis|conducted analysis of integrated bioinformatics data|wrote and revised the manuscript	conducted analysis of integrated bioinformatics data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5474932	28674547	H-SP	2	conducted adventitious root culture and transcriptome analysis|conducted analysis of integrated bioinformatics data|wrote and revised the manuscript	wrote and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5474932	28674547	HJK	2	conducted analysis of integrated bioinformatics data	conducted analysis of integrated bioinformatics data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5474932	28674547	MJ	2	conducted analysis of integrated bioinformatics data	conducted analysis of integrated bioinformatics data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5474932	28674547	N-HK	2	conducted analysis of integrated bioinformatics data	conducted analysis of integrated bioinformatics data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5474932	28674547	S-CL	2	conducted analysis of integrated bioinformatics data	conducted analysis of integrated bioinformatics data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5474932	28674547	SWK	2	conducted metabolome analysis	conducted metabolome analysis	Performed the experiments	Investigation	YES
5474932	28674547	T-JY	2	designed the research and organized the manuscript|wrote and revised the manuscript	designed the research and organized the manuscript	Conceived and designed the experiments	Methodology	YES
5474932	28674547	T-JY	2	designed the research and organized the manuscript|wrote and revised the manuscript	wrote and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5474932	28674547	YJK	2	conducted analysis of integrated bioinformatics data	conducted analysis of integrated bioinformatics data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5474932	28674547	YSL	2	conducted adventitious root culture and transcriptome analysis|conducted analysis of integrated bioinformatics data|wrote and revised the manuscript	conducted adventitious root culture and transcriptome analysis	Performed the experiments	Investigation	YES
5474932	28674547	YSL	2	conducted adventitious root culture and transcriptome analysis|conducted analysis of integrated bioinformatics data|wrote and revised the manuscript	conducted analysis of integrated bioinformatics data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5474932	28674547	YSL	2	conducted adventitious root culture and transcriptome analysis|conducted analysis of integrated bioinformatics data|wrote and revised the manuscript	wrote and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
2761414	19799780	CRR	2	participated in its design and coordination and helped to draft the manuscript	participated in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Project administration|Writing - Original Draft	YES
2761414	19799780	PG	2	participated in its design and coordination and helped to draft the manuscript	participated in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Project administration|Writing - Original Draft	YES
2761414	19799780	WB	2	participated in the design of the study and samples collection	participated in the design of the study and samples collection	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
2761414	19799780	YC	2	participated in its design and coordination and helped to draft the manuscript	participated in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Project administration|Writing - Original Draft	YES
4401541	25884407	DRH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401541	25884407	DRH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401541	25884407	DRH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401541	25884407	DRH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401541	25884407	DRH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401541	25884407	LHY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401541	25884407	LHY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401541	25884407	LHY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401541	25884407	LHY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401541	25884407	LHY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401541	25884407	MDW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401541	25884407	MDW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401541	25884407	MDW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401541	25884407	SP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4401541	25884407	SP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4163993	25224611	AK	2	conducted data collection, assisted with qualitative coding and quantitative data entry and queries	conducted data collection, assisted with qualitative coding and quantitative data entry and queries	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
4163993	25224611	AM	2	conducted data collection, assisted with qualitative coding and quantitative data entry and queries	conducted data collection, assisted with qualitative coding and quantitative data entry and queries	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
4163993	25224611	All authors	2	have reviewed and agreed to the content of the manuscript	have reviewed and agreed to the content of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4163993	25224611	EET	2	conceived of the study, led the analysis and drafted the manuscript	conceived of the study, led the analysis and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4163993	25224611	HK	2	conducted data collection, assisted with qualitative coding and quantitative data entry and queries	conducted data collection, assisted with qualitative coding and quantitative data entry and queries	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
4163993	25224611	JH	2	provided overall study coordination, managed the qualitative coding process and ran the quantitative analysis	provided overall study coordination, managed the qualitative coding process and ran the quantitative analysis	Performed the experiments	Investigation|Project administration	YES
4163993	25224611	JNB	2	made significant contributions to the study design, the analysis plan and gave extensive input into iterations of the manuscript	made significant contributions to the study design, the analysis plan and gave extensive input into iterations of the manuscript	Conceived and designed the experiments	Methodology	YES
4163993	25224611	SK	2	made significant contributions to the study design, the analysis plan and gave extensive input into iterations of the manuscript	made significant contributions to the study design, the analysis plan and gave extensive input into iterations of the manuscript	Conceived and designed the experiments	Methodology	YES
1579205	16965630	CDB	2	assisted with data collection, interpretation and the drafting of the manuscript	assisted with data collection, interpretation and the drafting of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
1579205	16965630	CPE	2	conceived of the study, participated in and managed all aspects of its design, coordination, data collection, and analysis, and drafted the manuscript	conceived of the study, participated in and managed all aspects of its design, coordination, data collection, and analysis, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Data curation|Formal analysis|Investigation|Methodology|Project administration|Writing - Original Draft	YES
1579205	16965630	ETM	2	participated in the study design, coordination, and data collection and assisted with the drafting of the manuscript	participated in the study design, coordination, and data collection and assisted with the drafting of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Project administration|Writing - Original Draft	YES
1579205	16965630	GAD	2	directed the laboratory and participated in all aspects of the study design, coordination, data analysis, and interpretation	directed the laboratory and participated in all aspects of the study design, coordination, data analysis, and interpretation	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology|Project administration|Supervision	YES
1579205	16965630	JMS	2	assisted with data collection and statistical analysis	assisted with data collection and statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4773404	26687096	All authors	2	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
4773404	26687096	D.W.	2	designed and directed different aspects of the study and wrote the paper	designed and directed different aspects of the study and wrote the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Original Draft	YES
4773404	26687096	F.G-M	2	designed and directed different aspects of the study and wrote the paper	designed and directed different aspects of the study and wrote the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Original Draft	YES
4773404	26687096	J.H.Y.	2	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
4773404	26687096	K.C.	2	designed and directed different aspects of the study and wrote the paper	designed and directed different aspects of the study and wrote the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Original Draft	YES
4773404	26687096	S.J.A.	2	designed and directed different aspects of the study and wrote the paper	designed and directed different aspects of the study and wrote the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Original Draft	YES
4773404	26687096	S.K.	2	designed and directed different aspects of the study and wrote the paper|reviewed the manuscript	designed and directed different aspects of the study and wrote the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Original Draft	YES
4773404	26687096	S.K.	2	designed and directed different aspects of the study and wrote the paper|reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
4773404	26687096	T.M.P.	2	designed and directed different aspects of the study and wrote the paper|reviewed the manuscript	designed and directed different aspects of the study and wrote the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Original Draft	YES
4773404	26687096	T.M.P.	2	designed and directed different aspects of the study and wrote the paper|reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5103432	27829352	AG	2	assisted mabh with	assisted mabh with	-	-	NO
5103432	27829352	BD	2	assisted mabh with	assisted mabh with	-	-	NO
5103432	27829352	JA	2	assisted mabh with	assisted mabh with	-	-	NO
4401542	25885113	JAF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Final approval	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401542	25885113	JAF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Final approval	Performed the experiments	Performed the experiments	Investigation	YES
4401542	25885113	JAF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Final approval	Analyzed the data	Analyzed the data	Formal analysis	YES
4401542	25885113	JAF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Final approval	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401542	25885113	JAF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Final approval	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401542	25885113	JAF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Final approval	Final approval	-	-	NO
4401542	25885113	LC	PLoS5	Analyzed the data|Wrote the paper|Final approval	Analyzed the data	Analyzed the data	Formal analysis	YES
4401542	25885113	LC	PLoS5	Analyzed the data|Wrote the paper|Final approval	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401542	25885113	LC	PLoS5	Analyzed the data|Wrote the paper|Final approval	Final approval	-	-	NO
4401542	25885113	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Acquisition of data|Final approval	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401542	25885113	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Acquisition of data|Final approval	Performed the experiments	Performed the experiments	Investigation	YES
4401542	25885113	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Acquisition of data|Final approval	Analyzed the data	Analyzed the data	Formal analysis	YES
4401542	25885113	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Acquisition of data|Final approval	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401542	25885113	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Acquisition of data|Final approval	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401542	25885113	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Acquisition of data|Final approval	Acquisition of data	Performed the experiments	Investigation	YES
4401542	25885113	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Acquisition of data|Final approval	Final approval	-	-	NO
4401542	25885113	MDM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Final approval	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401542	25885113	MDM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Final approval	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401542	25885113	MDM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Final approval	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401542	25885113	MDM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Final approval	Final approval	-	-	NO
4401542	25885113	MR	PLoS5	Conceived and designed the experiments|Wrote the paper|Final approval	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401542	25885113	MR	PLoS5	Conceived and designed the experiments|Wrote the paper|Final approval	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401542	25885113	MR	PLoS5	Conceived and designed the experiments|Wrote the paper|Final approval	Final approval	-	-	NO
4401542	25885113	MS	PLoS5	Performed the experiments|Wrote the paper|Acquisition of data|Final approval	Performed the experiments	Performed the experiments	Investigation	YES
4401542	25885113	MS	PLoS5	Performed the experiments|Wrote the paper|Acquisition of data|Final approval	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401542	25885113	MS	PLoS5	Performed the experiments|Wrote the paper|Acquisition of data|Final approval	Acquisition of data	Performed the experiments	Investigation	YES
4401542	25885113	MS	PLoS5	Performed the experiments|Wrote the paper|Acquisition of data|Final approval	Final approval	-	-	NO
4401542	25885113	OS	PLoS5	Conceived and designed the experiments|Wrote the paper|Final approval	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401542	25885113	OS	PLoS5	Conceived and designed the experiments|Wrote the paper|Final approval	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401542	25885113	OS	PLoS5	Conceived and designed the experiments|Wrote the paper|Final approval	Final approval	-	-	NO
4401542	25885113	RAS	PLoS5	Performed the experiments|Wrote the paper|Acquisition of data|Final approval	Performed the experiments	Performed the experiments	Investigation	YES
4401542	25885113	RAS	PLoS5	Performed the experiments|Wrote the paper|Acquisition of data|Final approval	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401542	25885113	RAS	PLoS5	Performed the experiments|Wrote the paper|Acquisition of data|Final approval	Acquisition of data	Performed the experiments	Investigation	YES
4401542	25885113	RAS	PLoS5	Performed the experiments|Wrote the paper|Acquisition of data|Final approval	Final approval	-	-	NO
5474966	28674553	AL	2	supervised the project	supervised the project	-	Supervision	YES
5474966	28674553	BB	2	designed the research, performed real time pcr and wrote the article	designed the research, performed real time pcr and wrote the article	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5474966	28674553	IL	2	enabled edx analyses	enabled edx analyses	Analyzed the data	Formal analysis	YES
5474966	28674553	JT	2	supervised the project	supervised the project	-	Supervision	YES
5474966	28674553	MV	2	performed edx analyses and contributed to the design of research and figure preparation	performed edx analyses and contributed to the design of research and figure preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology|Visualization	YES
5474966	28674553	MW	2	enabled edx analyses	enabled edx analyses	Analyzed the data	Formal analysis	YES
5474966	28674553	PCA	2	multivariate regression and network representation	multivariate regression and network representation	Analyzed the data	Formal analysis	YES
5474966	28674553	SB	2	considerably contributed to the real time pcr experiments and analysis	considerably contributed to the real time pcr experiments and analysis	Performed the experiments	Investigation	YES
5474966	28674553	all authors	2	discussed the results and commented on the article	discussed the results and commented on the article	-	-	NO
2770068	19821997	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
2770068	19821997	BES	2	contributed to the design and coordination of the study, contributed to data entering and cleaning, participated to interpreted and helped in drafting and revising the manuscript	contributed to the design and coordination of the study, contributed to data entering and cleaning, participated to interpreted and helped in drafting and revising the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Data curation|Formal analysis|Methodology|Project administration|Resources|Writing - Original Draft|Writing - Review & Editing	YES
2770068	19821997	MR	2	conceived the study, raised funds, participated in the design and coordination of the study, collected and cleaned data, interpreted data, drafted the manuscript	conceived the study, raised funds, participated in the design and coordination of the study, collected and cleaned data, interpreted data, drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Data curation|Formal analysis|Funding acquisition|Investigation|Methodology|Project administration|Writing - Original Draft	YES
2770068	19821997	NE	2	contributed to data cleaning, performed statistic analysis and interpretation, and helped in revising the manuscript	contributed to data cleaning, performed statistic analysis and interpretation, and helped in revising the manuscript	Analyzed the data|Wrote the paper	Data curation|Formal analysis|Writing - Review & Editing	YES
2770068	19821997	PN	2	conceived the study, participated in the design and coordination of the study, carried out data collection, coordinated laboratory sample processing, contributed to manuscript revision	conceived the study, participated in the design and coordination of the study, carried out data collection, coordinated laboratory sample processing, contributed to manuscript revision	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Data curation|Investigation|Methodology|Project administration|Writing - Review & Editing	YES
4332039	25536227	All authors	2	have given approval to the final version of the manuscript	have given approval to the final version of the manuscript	-	-	NO
4163994	25224612	All authors	2	contributed significantly to subsequent drafts and were also involved in project activities as discussed in the paper	contributed significantly to subsequent drafts and were also involved in project activities as discussed in the paper	Wrote the paper	Writing - Original Draft	YES
4163994	25224612	Allison Pack	2	also contributed to the literature review process	also contributed to the literature review process	-	Formal analysis	YES
4163994	25224612	Elizabeth Tolley	2	also contributed to the literature review process	also contributed to the literature review process	-	Formal analysis	YES
4163994	25224612	Sekou Sidibe	2	led the literature review process and wrote the first draft of the paper	led the literature review process and wrote the first draft of the paper	Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
1779772	17222342	MA	7	coordinated and executed study design and contributed to the manuscript	coordinated and executed study design and contributed to the manuscript	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Project administration	YES
1779772	17222342	MAW	7	conceived of study design and contributed to the manuscript	conceived of study design and contributed to the manuscript	Conceived and designed the experiments	Conceptualization|Methodology	YES
5103448	27832738	AK	2	sampled and expertly identified the specimens used in this analysis	sampled and expertly identified the specimens used in this analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5103448	27832738	ALD	2	designed the project|designed and executed the bioinformatics pipelines, performed the data analysis, and drafted the manuscript|jointly finalised the manuscript	designed the project	Conceived and designed the experiments	Methodology	YES
5103448	27832738	ALD	2	designed the project|designed and executed the bioinformatics pipelines, performed the data analysis, and drafted the manuscript|jointly finalised the manuscript	designed and executed the bioinformatics pipelines, performed the data analysis, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5103448	27832738	ALD	2	designed the project|designed and executed the bioinformatics pipelines, performed the data analysis, and drafted the manuscript|jointly finalised the manuscript	jointly finalised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5103448	27832738	AW	2	designed the project|jointly finalised the manuscript	designed the project	Conceived and designed the experiments	Methodology	YES
5103448	27832738	AW	2	designed the project|jointly finalised the manuscript	jointly finalised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5103448	27832738	All authors	2	read, commented on, and approved the final version of the manuscript	read, commented on, and approved the final version of the manuscript	-	-	NO
5103448	27832738	CB	2	contributed to the bioinformatics analysis and fine-tuning of the project	contributed to the bioinformatics analysis and fine-tuning of the project	-	Formal analysis	YES
5103448	27832738	CT	2	sampled and expertly identified the specimens used in this analysis	sampled and expertly identified the specimens used in this analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5103448	27832738	ER	2	sampled and expertly identified the specimens used in this analysis	sampled and expertly identified the specimens used in this analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5103448	27832738	MS	2	sampled and expertly identified the specimens used in this analysis	sampled and expertly identified the specimens used in this analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5103448	27832738	TW	2	sampled and expertly identified the specimens used in this analysis	sampled and expertly identified the specimens used in this analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3366242	22693432	M. L. Liou	2	contributed equally to this work	contributed equally to this work	-	-	NO
3366242	22693432	Y. J. Lin	2	contributed equally to this work	contributed equally to this work	-	-	NO
5475239	28674552	KN	PLoS52	performed the experiments|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5475239	28674552	KN	PLoS52	performed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5475239	28674552	MF	PLoS52	conceived and designed the experiments|contributed reagents/materials/analysis tools	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5475239	28674552	MF	PLoS52	conceived and designed the experiments|contributed reagents/materials/analysis tools	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5475239	28674552	MH	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5475239	28674552	MH	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5475239	28674552	MH	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5475239	28674552	MH	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5475239	28674552	TA	PLoS52	analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5475239	28674552	TA	PLoS52	analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4401544	25886576	CT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401544	25886576	CT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401544	25886576	CT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401544	25886576	CT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401544	25886576	SSC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401544	25886576	SSC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401544	25886576	SSC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401544	25886576	TR	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401544	25886576	TR	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401544	25886576	TR	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5767742	29171871	EH	2	conceived and designed the study|collected and compiled data|made substantial intellectual contributions to the work and commented and revised the report	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5767742	29171871	EH	2	conceived and designed the study|collected and compiled data|made substantial intellectual contributions to the work and commented and revised the report	collected and compiled data	Performed the experiments	Data curation|Investigation	YES
5767742	29171871	EH	2	conceived and designed the study|collected and compiled data|made substantial intellectual contributions to the work and commented and revised the report	made substantial intellectual contributions to the work and commented and revised the report	Wrote the paper	Writing - Review & Editing	YES
5767742	29171871	JCH	2	collected and compiled data|analysed and interpreted the data|wrote the report	collected and compiled data	Performed the experiments	Data curation|Investigation	YES
5767742	29171871	JCH	2	collected and compiled data|analysed and interpreted the data|wrote the report	analysed and interpreted the data	Analyzed the data	Formal analysis	YES
5767742	29171871	JCH	2	collected and compiled data|analysed and interpreted the data|wrote the report	wrote the report	Wrote the paper	Writing - Original Draft	YES
5767742	29171871	LH	2	conceived and designed the study|collected and compiled data|analysed and interpreted the data|wrote the report	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5767742	29171871	LH	2	conceived and designed the study|collected and compiled data|analysed and interpreted the data|wrote the report	collected and compiled data	Performed the experiments	Data curation|Investigation	YES
5767742	29171871	LH	2	conceived and designed the study|collected and compiled data|analysed and interpreted the data|wrote the report	analysed and interpreted the data	Analyzed the data	Formal analysis	YES
5767742	29171871	LH	2	conceived and designed the study|collected and compiled data|analysed and interpreted the data|wrote the report	wrote the report	Wrote the paper	Writing - Original Draft	YES
5767742	29171871	PA	2	conceived and designed the study|analysed and interpreted the data|made substantial intellectual contributions to the work and commented and revised the report	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5767742	29171871	PA	2	conceived and designed the study|analysed and interpreted the data|made substantial intellectual contributions to the work and commented and revised the report	analysed and interpreted the data	Analyzed the data	Formal analysis	YES
5767742	29171871	PA	2	conceived and designed the study|analysed and interpreted the data|made substantial intellectual contributions to the work and commented and revised the report	made substantial intellectual contributions to the work and commented and revised the report	Wrote the paper	Writing - Review & Editing	YES
5767742	29171871	SHN	2	performed statistical analysis|analysed and interpreted the data|made substantial intellectual contributions to the work and commented and revised the report	performed statistical analysis	Analyzed the data	Formal analysis	YES
5767742	29171871	SHN	2	performed statistical analysis|analysed and interpreted the data|made substantial intellectual contributions to the work and commented and revised the report	analysed and interpreted the data	Analyzed the data	Formal analysis	YES
5767742	29171871	SHN	2	performed statistical analysis|analysed and interpreted the data|made substantial intellectual contributions to the work and commented and revised the report	made substantial intellectual contributions to the work and commented and revised the report	Wrote the paper	Writing - Review & Editing	YES
5767742	29171871	TEM	2	conceived and designed the study|analysed and interpreted the data|made substantial intellectual contributions to the work and commented and revised the report	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5767742	29171871	TEM	2	conceived and designed the study|analysed and interpreted the data|made substantial intellectual contributions to the work and commented and revised the report	analysed and interpreted the data	Analyzed the data	Formal analysis	YES
5767742	29171871	TEM	2	conceived and designed the study|analysed and interpreted the data|made substantial intellectual contributions to the work and commented and revised the report	made substantial intellectual contributions to the work and commented and revised the report	Wrote the paper	Writing - Review & Editing	YES
5767742	29171871	TU	2	analysed and interpreted the data|made substantial intellectual contributions to the work and commented and revised the report	analysed and interpreted the data	Analyzed the data	Formal analysis	YES
5767742	29171871	TU	2	analysed and interpreted the data|made substantial intellectual contributions to the work and commented and revised the report	made substantial intellectual contributions to the work and commented and revised the report	Wrote the paper	Writing - Review & Editing	YES
5767742	29171871	WWS	2	performed statistical analysis|analysed and interpreted the data|wrote the report	performed statistical analysis	Analyzed the data	Formal analysis	YES
5767742	29171871	WWS	2	performed statistical analysis|analysed and interpreted the data|wrote the report	analysed and interpreted the data	Analyzed the data	Formal analysis	YES
5767742	29171871	WWS	2	performed statistical analysis|analysed and interpreted the data|wrote the report	wrote the report	Wrote the paper	Writing - Original Draft	YES
2774340	19845952	EEN	2	supervised genotyping, participated in study design and helped to draft the manuscript	supervised genotyping, participated in study design and helped to draft the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Supervision|Writing - Original Draft	YES
2774340	19845952	PT	2	participated in coordination of the study and helped to draft the manuscript	participated in coordination of the study and helped to draft the manuscript	Wrote the paper	Project administration|Writing - Original Draft	YES
2774340	19845952	SF	2	carried out genotyping and analysis of clinical data	carried out genotyping and analysis of clinical data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
2774340	19845952	SL	2	conceived of the study, participated in the design and coordination of the study, and drafted the manuscript	conceived of the study, participated in the design and coordination of the study, and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
2774340	19845952	SU	2	participated in coordination of the study and helped to draft the manuscript	participated in coordination of the study and helped to draft the manuscript	Wrote the paper	Project administration|Writing - Original Draft	YES
2774340	19845952	TR	2	carried out genotyping and analysis of clinical data	carried out genotyping and analysis of clinical data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
2774340	19845952	TS	2	participated in the design of the study, performed the statistical analysis, and helped to draft the manuscript	participated in the design of the study, performed the statistical analysis, and helped to draft the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
2774340	19845952	WP	2	participated in collection of clinical data and helped to draft the manuscript	participated in collection of clinical data and helped to draft the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4163995	25224610	AVDS	PLoS5	Conceived and designed the study|Implemented the study|Analyzed the data|Wrote the paper	Conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4163995	25224610	AVDS	PLoS5	Conceived and designed the study|Implemented the study|Analyzed the data|Wrote the paper	Implemented the study	Performed the experiments	Investigation	YES
4163995	25224610	AVDS	PLoS5	Conceived and designed the study|Implemented the study|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4163995	25224610	AVDS	PLoS5	Conceived and designed the study|Implemented the study|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4163995	25224610	EL	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4163995	25224610	EL	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4163995	25224610	ETM	PLoS5	Conceived and designed the study|Implemented the study|Analyzed the data	Conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4163995	25224610	ETM	PLoS5	Conceived and designed the study|Implemented the study|Analyzed the data	Implemented the study	Performed the experiments	Investigation	YES
4163995	25224610	ETM	PLoS5	Conceived and designed the study|Implemented the study|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4163995	25224610	JS	PLoS5	Conceived and designed the study|Implemented the study|Analyzed the data|Wrote the paper	Conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4163995	25224610	JS	PLoS5	Conceived and designed the study|Implemented the study|Analyzed the data|Wrote the paper	Implemented the study	Performed the experiments	Investigation	YES
4163995	25224610	JS	PLoS5	Conceived and designed the study|Implemented the study|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4163995	25224610	JS	PLoS5	Conceived and designed the study|Implemented the study|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4163995	25224610	MH	PLoS5	Implemented the study	Implemented the study	Performed the experiments	Investigation	YES
4163995	25224610	NL	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4163995	25224610	NL	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1831466	17359526	AAAE	7	participated, and assisted in the coordination of the study design	participated, and assisted in the coordination of the study design	Conceived and designed the experiments	Methodology|Project administration	YES
1831466	17359526	DAD	7	assisted in the coordination and execution of the study design	assisted in the coordination and execution of the study design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Project administration	YES
1831466	17359526	ET	7	assisted in the coordination and execution of the study design	assisted in the coordination and execution of the study design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Project administration	YES
1831466	17359526	MAW	7	conceived of the study, and participated in its design and coordination and helped to draft the manuscript	conceived of the study, and participated in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
1831466	17359526	ZB	7	participated, coordinated and executed the study design, and drafted the manuscript	participated, coordinated and executed the study design, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Project administration|Writing - Original Draft	YES
5103461	27829365	CTH	2	obtained the illumina reads|wrote the manuscript, with contributions from other authors	obtained the illumina reads	-	-	NO
5103461	27829365	CTH	2	obtained the illumina reads|wrote the manuscript, with contributions from other authors	wrote the manuscript, with contributions from other authors	Wrote the paper	Writing - Original Draft	YES
5103461	27829365	DL	2	designed the study|obtained the illumina reads|wrote the manuscript, with contributions from other authors	designed the study	Conceived and designed the experiments	Methodology	YES
5103461	27829365	DL	2	designed the study|obtained the illumina reads|wrote the manuscript, with contributions from other authors	obtained the illumina reads	-	-	NO
5103461	27829365	DL	2	designed the study|obtained the illumina reads|wrote the manuscript, with contributions from other authors	wrote the manuscript, with contributions from other authors	Wrote the paper	Writing - Original Draft	YES
5103461	27829365	JPS	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5103461	27829365	MAC	2	performed the annotation of specific genes|wrote the manuscript, with contributions from other authors	performed the annotation of specific genes	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5103461	27829365	MAC	2	performed the annotation of specific genes|wrote the manuscript, with contributions from other authors	wrote the manuscript, with contributions from other authors	Wrote the paper	Writing - Original Draft	YES
5103461	27829365	MDP	2	performed the annotation of specific genes|wrote the manuscript, with contributions from other authors	performed the annotation of specific genes	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5103461	27829365	MDP	2	performed the annotation of specific genes|wrote the manuscript, with contributions from other authors	wrote the manuscript, with contributions from other authors	Wrote the paper	Writing - Original Draft	YES
5103461	27829365	MM	2	carried out phylogenetic analyses|performed the annotation of specific genes|wrote the manuscript, with contributions from other authors	carried out phylogenetic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5103461	27829365	MM	2	carried out phylogenetic analyses|performed the annotation of specific genes|wrote the manuscript, with contributions from other authors	performed the annotation of specific genes	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5103461	27829365	MM	2	carried out phylogenetic analyses|performed the annotation of specific genes|wrote the manuscript, with contributions from other authors	wrote the manuscript, with contributions from other authors	Wrote the paper	Writing - Original Draft	YES
5103461	27829365	NB	2	designed the study|performed genome assembly, gene predictions and annotations, and orthology|carried out phylogenetic analyses|wrote the manuscript, with contributions from other authors	designed the study	Conceived and designed the experiments	Methodology	YES
5103461	27829365	NB	2	designed the study|performed genome assembly, gene predictions and annotations, and orthology|carried out phylogenetic analyses|wrote the manuscript, with contributions from other authors	performed genome assembly, gene predictions and annotations, and orthology	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5103461	27829365	NB	2	designed the study|performed genome assembly, gene predictions and annotations, and orthology|carried out phylogenetic analyses|wrote the manuscript, with contributions from other authors	carried out phylogenetic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5103461	27829365	NB	2	designed the study|performed genome assembly, gene predictions and annotations, and orthology|carried out phylogenetic analyses|wrote the manuscript, with contributions from other authors	wrote the manuscript, with contributions from other authors	Wrote the paper	Writing - Original Draft	YES
5103461	27829365	PG	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
4401545	25884400	AR	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401545	25884400	AVR	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401545	25884400	AVR	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401545	25884400	AVR	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401545	25884400	BS	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401545	25884400	DR	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401545	25884400	IM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401545	25884400	LS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401545	25884400	LS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401545	25884400	LS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5113919	27633407	C P Stanley	2	performed the research and approved the final version|designed the research study and approved the final version|analysed the data and approved the final version|wrote the paper and approved the final version	performed the research and approved the final version	Performed the experiments	Investigation	YES
5113919	27633407	C P Stanley	2	performed the research and approved the final version|designed the research study and approved the final version|analysed the data and approved the final version|wrote the paper and approved the final version	designed the research study and approved the final version	Conceived and designed the experiments	Methodology	YES
5113919	27633407	C P Stanley	2	performed the research and approved the final version|designed the research study and approved the final version|analysed the data and approved the final version|wrote the paper and approved the final version	analysed the data and approved the final version	Analyzed the data	Formal analysis	YES
5113919	27633407	C P Stanley	2	performed the research and approved the final version|designed the research study and approved the final version|analysed the data and approved the final version|wrote the paper and approved the final version	wrote the paper and approved the final version	Wrote the paper	Writing - Original Draft	YES
5113919	27633407	C Tufarelli	2	performed the research and approved the final version	performed the research and approved the final version	Performed the experiments	Investigation	YES
5113919	27633407	S E Osullivan	2	performed the research and approved the final version|designed the research study and approved the final version|analysed the data and approved the final version|wrote the paper and approved the final version	performed the research and approved the final version	Performed the experiments	Investigation	YES
5113919	27633407	S E Osullivan	2	performed the research and approved the final version|designed the research study and approved the final version|analysed the data and approved the final version|wrote the paper and approved the final version	designed the research study and approved the final version	Conceived and designed the experiments	Methodology	YES
5113919	27633407	S E Osullivan	2	performed the research and approved the final version|designed the research study and approved the final version|analysed the data and approved the final version|wrote the paper and approved the final version	analysed the data and approved the final version	Analyzed the data	Formal analysis	YES
5113919	27633407	S E Osullivan	2	performed the research and approved the final version|designed the research study and approved the final version|analysed the data and approved the final version|wrote the paper and approved the final version	wrote the paper and approved the final version	Wrote the paper	Writing - Original Draft	YES
5113919	27633407	W H Hind	2	performed the research and approved the final version	performed the research and approved the final version	Performed the experiments	Investigation	YES
1852303	17386093	ASF	2	assisted with data collection and manuscript revision	assisted with data collection and manuscript revision	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
1852303	17386093	AWG	2	conceived and designed the study, assisted with statistical analyses and their interpretation, and drafted the manuscript	conceived and designed the study, assisted with statistical analyses and their interpretation, and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
1852303	17386093	CF	2	assisted with data collection and manuscript revision	assisted with data collection and manuscript revision	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
1852303	17386093	KJN	2	assisted with data collection and manuscript revision	assisted with data collection and manuscript revision	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
1852303	17386093	LSA	2	conceived and designed the study, acquired data, performed the statistical analyses and their interpretation, and drafted each manuscript version	conceived and designed the study, acquired data, performed the statistical analyses and their interpretation, and drafted each manuscript version	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
1852303	17386093	PCC	2	assisted with subject recruitment and manuscript revision	assisted with subject recruitment and manuscript revision	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
1852303	17386093	PSM	2	assisted with subject recruitment and manuscript revision	assisted with subject recruitment and manuscript revision	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
1852303	17386093	TLW	2	assisted with subject recruitment and manuscript revision	assisted with subject recruitment and manuscript revision	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5771464	28981139	All authors	PLoS52	conceived of and designed the experimental protocol|read and approved the final manuscript	conceived of and designed the experimental protocol	Conceived and designed the experiments	Conceptualization|Methodology	YES
5771464	28981139	All authors	PLoS52	conceived of and designed the experimental protocol|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5771464	28981139	MY	PLoS52	analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
5771464	28981139	XX	PLoS52	collected the data|wrote the first draft of the manuscript|contributed equally to this work and should be considered co-first authors	collected the data	Performed the experiments	Investigation	YES
5771464	28981139	XX	PLoS52	collected the data|wrote the first draft of the manuscript|contributed equally to this work and should be considered co-first authors	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
5771464	28981139	XX	PLoS52	collected the data|wrote the first draft of the manuscript|contributed equally to this work and should be considered co-first authors	contributed equally to this work and should be considered co-first authors	-	-	NO
5475338	28674541	CC	2	conceived experiments	conceived experiments	Conceived and designed the experiments	Conceptualization	YES
5475338	28674541	CM	2	conceived experiments	conceived experiments	Conceived and designed the experiments	Conceptualization	YES
5475338	28674541	HK	2	conceived experiments|wrote the manuscript	conceived experiments	Conceived and designed the experiments	Conceptualization	YES
5475338	28674541	HK	2	conceived experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5475338	28674541	IF	2	analyzed data|secured funding	analyzed data	Analyzed the data	Formal analysis	YES
5475338	28674541	IF	2	analyzed data|secured funding	secured funding	-	Funding acquisition	YES
5475338	28674541	JL	2	conceived experiments|wrote the manuscript	conceived experiments	Conceived and designed the experiments	Conceptualization	YES
5475338	28674541	JL	2	conceived experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5475338	28674541	MA	2	conceived experiments	conceived experiments	Conceived and designed the experiments	Conceptualization	YES
5475338	28674541	MK	2	conceived experiments	conceived experiments	Conceived and designed the experiments	Conceptualization	YES
5475338	28674541	RP	2	conceived experiments|wrote the manuscript|secured funding	conceived experiments	Conceived and designed the experiments	Conceptualization	YES
5475338	28674541	RP	2	conceived experiments|wrote the manuscript|secured funding	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5475338	28674541	RP	2	conceived experiments|wrote the manuscript|secured funding	secured funding	-	Funding acquisition	YES
5475338	28674541	SB	2	provided expertise and feedback with the faire experiments	provided expertise and feedback with the faire experiments	-	-	NO
5475338	28674541	UC	2	provided expertise and feedback with the faire experiments|secured funding	provided expertise and feedback with the faire experiments	-	-	NO
5475338	28674541	UC	2	provided expertise and feedback with the faire experiments|secured funding	secured funding	-	Funding acquisition	YES
5475338	28674541	YB	2	conceived experiments|secured funding	conceived experiments	Conceived and designed the experiments	Conceptualization	YES
5475338	28674541	YB	2	conceived experiments|secured funding	secured funding	-	Funding acquisition	YES
2777914	19895691	AWH	2	grew and treated the cells and performed the cytotoxicity assays and immunoassays for virus titer	grew and treated the cells and performed the cytotoxicity assays and immunoassays for virus titer	Performed the experiments	Investigation	YES
2777914	19895691	DMW	2	provided essential information regarding the stability of wr1065 in culture, and funding to share the cost of the amifostine synthesis	provided essential information regarding the stability of wr1065 in culture, and funding to share the cost of the amifostine synthesis	Performed the experiments	Funding acquisition|Investigation	YES
2777914	19895691	GF	2	provided the monkey cells and was involved in the conceptual design of the siv experiments	provided the monkey cells and was involved in the conceptual design of the siv experiments	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceptualization|Investigation|Methodology|Resources	YES
2777914	19895691	GMS	2	who contributed labs with p3 containment where hiv-1 could be used|also provided critical conceptual input	who contributed labs with p3 containment where hiv-1 could be used	-	-	NO
2777914	19895691	GMS	2	who contributed labs with p3 containment where hiv-1 could be used|also provided critical conceptual input	also provided critical conceptual input	Conceived and designed the experiments	Conceptualization	YES
2777914	19895691	JB	2	grew and treated the cells and performed the cytotoxicity assays and immunoassays for virus titer	grew and treated the cells and performed the cytotoxicity assays and immunoassays for virus titer	Performed the experiments	Investigation	YES
2777914	19895691	MCP	2	wrote the protocols, calculated the data, prepared the graphs and tables and wrote the paper	wrote the protocols, calculated the data, prepared the graphs and tables and wrote the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
2777914	19895691	OAO	2	grew and treated the cells and performed the cytotoxicity assays and immunoassays for virus titer|provided important conceptual input regarding the cytotoxicity assays	grew and treated the cells and performed the cytotoxicity assays and immunoassays for virus titer	Performed the experiments	Investigation	YES
2777914	19895691	OAO	2	grew and treated the cells and performed the cytotoxicity assays and immunoassays for virus titer|provided important conceptual input regarding the cytotoxicity assays	provided important conceptual input regarding the cytotoxicity assays	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
2777914	19895691	VEW	2	provided essential information regarding the stability of wr1065 in culture, and funding to share the cost of the amifostine synthesis	provided essential information regarding the stability of wr1065 in culture, and funding to share the cost of the amifostine synthesis	Performed the experiments	Funding acquisition|Investigation	YES
3614831	23675240	AH	2	participated in the design of the study and helped to draft the manuscript	participated in the design of the study and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3614831	23675240	AM	2	participated in the execution of the study	participated in the execution of the study	Performed the experiments	Investigation	YES
3614831	23675240	GF	2	approved the design of the study and helped to draft the manuscript	approved the design of the study and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3614831	23675240	IS	2	participated in the design of the study and helped to draft the manuscript	participated in the design of the study and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3614831	23675240	KT	2	approved the design of the study and helped to draft the manuscript	approved the design of the study and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3614831	23675240	MO	2	participated in the execution of the study|participated in the execution of the study	participated in the execution of the study	Performed the experiments	Investigation	YES
3614831	23675240	MO	2	participated in the execution of the study|participated in the execution of the study	participated in the execution of the study	Performed the experiments	Investigation	YES
5113977	27565382	AP	2	conducted the experiments	conducted the experiments	Performed the experiments	Investigation	YES
5113977	27565382	All authors	2	contributed to proof reading and manuscript revision	contributed to proof reading and manuscript revision	Wrote the paper	Writing - Review & Editing	YES
5113977	27565382	DG	2	designed the experiments|conducted the experiments|analysed the data and wrote the first draft of the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5113977	27565382	DG	2	designed the experiments|conducted the experiments|analysed the data and wrote the first draft of the manuscript	conducted the experiments	Performed the experiments	Investigation	YES
5113977	27565382	DG	2	designed the experiments|conducted the experiments|analysed the data and wrote the first draft of the manuscript	analysed the data and wrote the first draft of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5113977	27565382	JLW	2	conducted the experiments	conducted the experiments	Performed the experiments	Investigation	YES
5113977	27565382	MEW	2	conducted the experiments	conducted the experiments	Performed the experiments	Investigation	YES
5113977	27565382	MW	2	designed the experiments|analysed the data and wrote the first draft of the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5113977	27565382	MW	2	designed the experiments|analysed the data and wrote the first draft of the manuscript	analysed the data and wrote the first draft of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5113977	27565382	RT	2	conducted the experiments	conducted the experiments	Performed the experiments	Investigation	YES
5113977	27565382	SL	2	conducted the experiments	conducted the experiments	Performed the experiments	Investigation	YES
4163996	25224618	BF	1	Study conception and design|Data collection|Data coding and analysis|Data interpretation and synthesis|Manuscript writing	Study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4163996	25224618	BF	1	Study conception and design|Data collection|Data coding and analysis|Data interpretation and synthesis|Manuscript writing	Data collection	Performed the experiments	Investigation	YES
4163996	25224618	BF	1	Study conception and design|Data collection|Data coding and analysis|Data interpretation and synthesis|Manuscript writing	Data coding and analysis	Analyzed the data	Formal analysis	YES
4163996	25224618	BF	1	Study conception and design|Data collection|Data coding and analysis|Data interpretation and synthesis|Manuscript writing	Data interpretation and synthesis	Analyzed the data	Formal analysis	YES
4163996	25224618	BF	1	Study conception and design|Data collection|Data coding and analysis|Data interpretation and synthesis|Manuscript writing	Manuscript writing	Wrote the paper	Writing - Original Draft	YES
4163996	25224618	EM	1	Study conception and design|Data collection|Data coding and analysis|Data interpretation and synthesis|Manuscript writing	Study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4163996	25224618	EM	1	Study conception and design|Data collection|Data coding and analysis|Data interpretation and synthesis|Manuscript writing	Data collection	Performed the experiments	Investigation	YES
4163996	25224618	EM	1	Study conception and design|Data collection|Data coding and analysis|Data interpretation and synthesis|Manuscript writing	Data coding and analysis	Analyzed the data	Formal analysis	YES
4163996	25224618	EM	1	Study conception and design|Data collection|Data coding and analysis|Data interpretation and synthesis|Manuscript writing	Data interpretation and synthesis	Analyzed the data	Formal analysis	YES
4163996	25224618	EM	1	Study conception and design|Data collection|Data coding and analysis|Data interpretation and synthesis|Manuscript writing	Manuscript writing	Wrote the paper	Writing - Original Draft	YES
4163996	25224618	ML	1	Study conception and design|Data collection|Data coding and analysis|Data interpretation and synthesis|Manuscript writing	Study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4163996	25224618	ML	1	Study conception and design|Data collection|Data coding and analysis|Data interpretation and synthesis|Manuscript writing	Data collection	Performed the experiments	Investigation	YES
4163996	25224618	ML	1	Study conception and design|Data collection|Data coding and analysis|Data interpretation and synthesis|Manuscript writing	Data coding and analysis	Analyzed the data	Formal analysis	YES
4163996	25224618	ML	1	Study conception and design|Data collection|Data coding and analysis|Data interpretation and synthesis|Manuscript writing	Data interpretation and synthesis	Analyzed the data	Formal analysis	YES
4163996	25224618	ML	1	Study conception and design|Data collection|Data coding and analysis|Data interpretation and synthesis|Manuscript writing	Manuscript writing	Wrote the paper	Writing - Original Draft	YES
4163996	25224618	RL	1	Study conception and design|Data collection|Data coding and analysis|Data interpretation and synthesis|Manuscript writing	Study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4163996	25224618	RL	1	Study conception and design|Data collection|Data coding and analysis|Data interpretation and synthesis|Manuscript writing	Data collection	Performed the experiments	Investigation	YES
4163996	25224618	RL	1	Study conception and design|Data collection|Data coding and analysis|Data interpretation and synthesis|Manuscript writing	Data coding and analysis	Analyzed the data	Formal analysis	YES
4163996	25224618	RL	1	Study conception and design|Data collection|Data coding and analysis|Data interpretation and synthesis|Manuscript writing	Data interpretation and synthesis	Analyzed the data	Formal analysis	YES
4163996	25224618	RL	1	Study conception and design|Data collection|Data coding and analysis|Data interpretation and synthesis|Manuscript writing	Manuscript writing	Wrote the paper	Writing - Original Draft	YES
4163996	25224618	RP	1	Study conception and design|Data collection|Data coding and analysis|Data interpretation and synthesis|Manuscript writing	Study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4163996	25224618	RP	1	Study conception and design|Data collection|Data coding and analysis|Data interpretation and synthesis|Manuscript writing	Data collection	Performed the experiments	Investigation	YES
4163996	25224618	RP	1	Study conception and design|Data collection|Data coding and analysis|Data interpretation and synthesis|Manuscript writing	Data coding and analysis	Analyzed the data	Formal analysis	YES
4163996	25224618	RP	1	Study conception and design|Data collection|Data coding and analysis|Data interpretation and synthesis|Manuscript writing	Data interpretation and synthesis	Analyzed the data	Formal analysis	YES
4163996	25224618	RP	1	Study conception and design|Data collection|Data coding and analysis|Data interpretation and synthesis|Manuscript writing	Manuscript writing	Wrote the paper	Writing - Original Draft	YES
4163996	25224618	RW	1	Study conception and design|Data interpretation and synthesis|Manuscript writing	Study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4163996	25224618	RW	1	Study conception and design|Data interpretation and synthesis|Manuscript writing	Data interpretation and synthesis	Analyzed the data	Formal analysis	YES
4163996	25224618	RW	1	Study conception and design|Data interpretation and synthesis|Manuscript writing	Manuscript writing	Wrote the paper	Writing - Original Draft	YES
4163996	25224618	SS	1	Study conception and design|Data collection|Data coding and analysis|Data interpretation and synthesis|Manuscript writing	Study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4163996	25224618	SS	1	Study conception and design|Data collection|Data coding and analysis|Data interpretation and synthesis|Manuscript writing	Data collection	Performed the experiments	Investigation	YES
4163996	25224618	SS	1	Study conception and design|Data collection|Data coding and analysis|Data interpretation and synthesis|Manuscript writing	Data coding and analysis	Analyzed the data	Formal analysis	YES
4163996	25224618	SS	1	Study conception and design|Data collection|Data coding and analysis|Data interpretation and synthesis|Manuscript writing	Data interpretation and synthesis	Analyzed the data	Formal analysis	YES
4163996	25224618	SS	1	Study conception and design|Data collection|Data coding and analysis|Data interpretation and synthesis|Manuscript writing	Manuscript writing	Wrote the paper	Writing - Original Draft	YES
4401546	25884405	CHH	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401546	25884405	CHH	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401546	25884405	CHT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401546	25884405	CHT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401546	25884405	CHT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401546	25884405	SHS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401546	25884405	TN	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401546	25884405	TSD	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401546	25884405	TSD	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401546	25884405	TW	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401546	25884405	TW	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401546	25884405	YCL	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401546	25884405	YCL	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5103508	27829355	CJ	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5103508	27829355	LW	PLoS52	conceived the study|performed most of the experiments|analyzed the data|wrote the article with contributions of all the authors	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5103508	27829355	LW	PLoS52	conceived the study|performed most of the experiments|analyzed the data|wrote the article with contributions of all the authors	performed most of the experiments	Performed the experiments	Investigation	YES
5103508	27829355	LW	PLoS52	conceived the study|performed most of the experiments|analyzed the data|wrote the article with contributions of all the authors	analyzed the data	Analyzed the data	Formal analysis	YES
5103508	27829355	LW	PLoS52	conceived the study|performed most of the experiments|analyzed the data|wrote the article with contributions of all the authors	wrote the article with contributions of all the authors	Wrote the paper	Writing - Original Draft	YES
5103508	27829355	XH	PLoS52	provided technical assistance	provided technical assistance	Performed the experiments	Investigation	YES
5103508	27829355	XW	PLoS52	conceived the study|supervised the experiments	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5103508	27829355	XW	PLoS52	conceived the study|supervised the experiments	supervised the experiments	-	Supervision	YES
5103508	27829355	XY	PLoS52	helped with the sample collecting	helped with the sample collecting	Performed the experiments	Investigation	YES
5103508	27829355	YW	PLoS52	supervised the experiments	supervised the experiments	-	Supervision	YES
5103508	27829355	ZF	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5103508	27829355	ZL	PLoS52	provided technical assistance	provided technical assistance	Performed the experiments	Investigation	YES
4095929	24922178	All authors	2	have given approval to the final version of the manuscript	have given approval to the final version of the manuscript	-	-	NO
4442281	26078976	Lional Rajappa	2	contributed equally to the review	contributed equally to the review	-	-	NO
4442281	26078976	Paola Munoz-Tello	2	contributed equally to the review	contributed equally to the review	-	-	NO
5475386	28674545	CeG	2	addressed the scientific direction of the evaluation to late blight resistance	addressed the scientific direction of the evaluation to late blight resistance	-	-	NO
5475386	28674545	ChG	2	provided scientific direction and access to the differential transcriptome analysis data base and contributed to the data analysis	provided scientific direction and access to the differential transcriptome analysis data base and contributed to the data analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources|Software	YES
5475386	28674545	JJ-G	2	carried out the data analysis of the differential transcriptome experiment and provided the list of candidate genes	carried out the data analysis of the differential transcriptome experiment and provided the list of candidate genes	Analyzed the data	Formal analysis	YES
5475386	28674545	MA	2	designed and carried out the phenotypic evaluation in field conditions	designed and carried out the phenotypic evaluation in field conditions	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5475386	28674545	MD	2	designed and carried out the phenotypic evaluation in field conditions	designed and carried out the phenotypic evaluation in field conditions	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5475386	28674545	MFA	2	designed, planned, and carried out the experiments for genotyping, snp data analysis, and association mapping|prepared the draft of the manuscript	designed, planned, and carried out the experiments for genotyping, snp data analysis, and association mapping	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation|Methodology	YES
5475386	28674545	MFA	2	designed, planned, and carried out the experiments for genotyping, snp data analysis, and association mapping|prepared the draft of the manuscript	prepared the draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
5475386	28674545	TM	2	generated the basic idea for the research in association analysis, planned and designed experiments for genotyping and supervised the project|designed the manuscript and corrected it	generated the basic idea for the research in association analysis, planned and designed experiments for genotyping and supervised the project	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology|Supervision	YES
5475386	28674545	TM	2	generated the basic idea for the research in association analysis, planned and designed experiments for genotyping and supervised the project|designed the manuscript and corrected it	designed the manuscript and corrected it	Conceived and designed the experiments|Wrote the paper	Writing - Review & Editing	YES
2780452	19891783	CCT	2	was responsible for the overall experimental design, implementation of the project, data interpretation and manuscript writing	was responsible for the overall experimental design, implementation of the project, data interpretation and manuscript writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
2780452	19891783	HIV	2	drugs and data interpretation	drugs and data interpretation	Analyzed the data	Formal analysis	YES
2780452	19891783	MBA	2	helped with data interpretation and manuscript review	helped with data interpretation and manuscript review	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
2780452	19891783	PE	2	helped with laboratory experiments and data analysis	helped with laboratory experiments and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
2780452	19891783	RT-SHIV	2	helped with discussion on the study progress and review of manuscript	helped with discussion on the study progress and review of manuscript	Wrote the paper	Writing - Review & Editing	YES
2780452	19891783	YJ	2	carried out the experiments, performed data analysis and wrote the initial draft of the manuscript	carried out the experiments, performed data analysis and wrote the initial draft of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
2783021	19930642	AR	PLoS52	collected data or performed various measurements for the study|helped in the data analysis and interpretation	collected data or performed various measurements for the study	Performed the experiments	Investigation	YES
2783021	19930642	AR	PLoS52	collected data or performed various measurements for the study|helped in the data analysis and interpretation	helped in the data analysis and interpretation	Analyzed the data	Formal analysis	YES
2783021	19930642	CA-V	PLoS52	designed the study|analyzed the data|wrote the first draft of the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
2783021	19930642	CA-V	PLoS52	designed the study|analyzed the data|wrote the first draft of the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
2783021	19930642	CA-V	PLoS52	designed the study|analyzed the data|wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
2783021	19930642	GA	PLoS52	analyzed the data|collected data or performed various measurements for the study|helped in the data analysis and interpretation	analyzed the data	Analyzed the data	Formal analysis	YES
2783021	19930642	GA	PLoS52	analyzed the data|collected data or performed various measurements for the study|helped in the data analysis and interpretation	collected data or performed various measurements for the study	Performed the experiments	Investigation	YES
2783021	19930642	GA	PLoS52	analyzed the data|collected data or performed various measurements for the study|helped in the data analysis and interpretation	helped in the data analysis and interpretation	Analyzed the data	Formal analysis	YES
2783021	19930642	JC	PLoS52	contributed to the final version of the manuscript|supervised the laboratory determinations	contributed to the final version of the manuscript	-	-	NO
2783021	19930642	JC	PLoS52	contributed to the final version of the manuscript|supervised the laboratory determinations	supervised the laboratory determinations	-	Supervision	YES
2783021	19930642	JJ	PLoS52	designed the study|contributed to the final version of the manuscript|supervised the laboratory determinations	designed the study	Conceived and designed the experiments	Methodology	YES
2783021	19930642	JJ	PLoS52	designed the study|contributed to the final version of the manuscript|supervised the laboratory determinations	contributed to the final version of the manuscript	-	-	NO
2783021	19930642	JJ	PLoS52	designed the study|contributed to the final version of the manuscript|supervised the laboratory determinations	supervised the laboratory determinations	-	Supervision	YES
2783021	19930642	JMA	PLoS52	contributed to the final version of the manuscript	contributed to the final version of the manuscript	-	-	NO
2783021	19930642	LF-S	PLoS52	collected data or performed various measurements for the study	collected data or performed various measurements for the study	Performed the experiments	Investigation	YES
2783021	19930642	RB-D	PLoS52	analyzed the data|collected data or performed various measurements for the study|helped in the data analysis and interpretation	analyzed the data	Analyzed the data	Formal analysis	YES
2783021	19930642	RB-D	PLoS52	analyzed the data|collected data or performed various measurements for the study|helped in the data analysis and interpretation	collected data or performed various measurements for the study	Performed the experiments	Investigation	YES
2783021	19930642	RB-D	PLoS52	analyzed the data|collected data or performed various measurements for the study|helped in the data analysis and interpretation	helped in the data analysis and interpretation	Analyzed the data	Formal analysis	YES
4401547	25884211	CQ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4401547	25884211	CQ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4401547	25884211	CQ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401547	25884211	YL	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5887888	29405291	LU	2	contributed to the data extraction and analysis process of this study	contributed to the data extraction and analysis process of this study	Analyzed the data	Data curation|Formal analysis	YES
5887888	29405291	S Shi	2	contributed to the design of the study and manuscript writing|contributed to the financial support of this study	contributed to the design of the study and manuscript writing	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5887888	29405291	S Shi	2	contributed to the design of the study and manuscript writing|contributed to the financial support of this study	contributed to the financial support of this study	-	Funding acquisition	YES
5887888	29405291	Y Zheng	2	contributed to the revision of the manuscript	contributed to the revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
1890280	17540028	LJ	2	both conceived of the study|participated in the design of the study and contributed to the writing of the manuscript	both conceived of the study	Conceived and designed the experiments	Conceptualization	YES
1890280	17540028	LJ	2	both conceived of the study|participated in the design of the study and contributed to the writing of the manuscript	participated in the design of the study and contributed to the writing of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
1890280	17540028	MB	2	both conceived of the study|carried out the statistical analyses and contributed to the writing of the manuscript	both conceived of the study	Conceived and designed the experiments	Conceptualization	YES
1890280	17540028	MB	2	both conceived of the study|carried out the statistical analyses and contributed to the writing of the manuscript	carried out the statistical analyses and contributed to the writing of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4163997	25224621	Cynthia Geary	2	led the writing process and wrote the first draft of the paper	led the writing process and wrote the first draft of the paper	Wrote the paper	Writing - Original Draft	YES
4163997	25224621	Elizabeth Bukusi	2	contributed significantly to the ideas and opinions set forth in the paper	contributed significantly to the ideas and opinions set forth in the paper	Conceived and designed the experiments	Conceptualization	YES
5103509	27829357	All authors	PLoS52	provided intellectual input and approved the final manuscript	provided intellectual input and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5103509	27829357	HZ	PLoS52	conceived and designed the research|performed the experiments|performed the bioinformatics analyses and edited the manuscript|wrote the manuscript	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5103509	27829357	HZ	PLoS52	conceived and designed the research|performed the experiments|performed the bioinformatics analyses and edited the manuscript|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5103509	27829357	HZ	PLoS52	conceived and designed the research|performed the experiments|performed the bioinformatics analyses and edited the manuscript|wrote the manuscript	performed the bioinformatics analyses and edited the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
5103509	27829357	HZ	PLoS52	conceived and designed the research|performed the experiments|performed the bioinformatics analyses and edited the manuscript|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5103509	27829357	LL	PLoS52	performed the bioinformatics analyses and edited the manuscript	performed the bioinformatics analyses and edited the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
5103509	27829357	NTC	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5103509	27829357	PA	PLoS52	conceived and designed the research	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5103509	27829357	WX	PLoS52	conceived and designed the research|wrote the manuscript	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5103509	27829357	WX	PLoS52	conceived and designed the research|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5103509	27829357	XZ	PLoS52	performed the bioinformatics analyses and edited the manuscript	performed the bioinformatics analyses and edited the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
2784795	19922674	PT	2	hypothesized and collected references|critically revised the manuscript	hypothesized and collected references	Performed the experiments	Investigation	YES
2784795	19922674	PT	2	hypothesized and collected references|critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
2784795	19922674	RM	2	hypothesized and collected references|drafted the first version	hypothesized and collected references	Performed the experiments	Investigation	YES
2784795	19922674	RM	2	hypothesized and collected references|drafted the first version	drafted the first version	Wrote the paper	Writing - Original Draft	YES
2784795	19922674	SS	2	hypothesized and collected references|drafted the first version	hypothesized and collected references	Performed the experiments	Investigation	YES
2784795	19922674	SS	2	hypothesized and collected references|drafted the first version	drafted the first version	Wrote the paper	Writing - Original Draft	YES
4401548	25886387	AR	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401548	25886387	AVSH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401548	25886387	AVSH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401548	25886387	AVSH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401548	25886387	DWC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401548	25886387	KSE	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401548	25886387	KSE	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401548	25886387	MKE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401548	25886387	MKE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401548	25886387	MKE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401548	25886387	MKE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401548	25886387	SJC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401548	25886387	SJC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401548	25886387	SJC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5475392	28674544	DZ	2	conceived and designed experiment|revised the manuscript|obtained funding and is responsible for this article	conceived and designed experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5475392	28674544	DZ	2	conceived and designed experiment|revised the manuscript|obtained funding and is responsible for this article	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5475392	28674544	DZ	2	conceived and designed experiment|revised the manuscript|obtained funding and is responsible for this article	obtained funding and is responsible for this article	-	Funding acquisition	YES
5475392	28674544	MQ	2	performed the experiments and data analysis|provided valuable advice on the manuscript	performed the experiments and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5475392	28674544	MQ	2	performed the experiments and data analysis|provided valuable advice on the manuscript	provided valuable advice on the manuscript	-	-	NO
5475392	28674544	QD	2	provided valuable advice on the manuscript|revised the manuscript	provided valuable advice on the manuscript	-	-	NO
5475392	28674544	QD	2	provided valuable advice on the manuscript|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5475392	28674544	WS	2	performed the experiments and data analysis|wrote the manuscript	performed the experiments and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5475392	28674544	WS	2	performed the experiments and data analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6001568	29578574	All authors	2	then contributed iteratively and equally to the development of ideas and refinement of the paper	then contributed iteratively and equally to the development of ideas and refinement of the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
6001568	29578574	EJCI	2	by the editor	by the editor	-	-	NO
6001568	29578574	KM	2	wrote an initial outline for the paper	wrote an initial outline for the paper	Wrote the paper	Writing - Original Draft	YES
6001568	29578574	ST	2	wrote an initial outline for the paper	wrote an initial outline for the paper	Wrote the paper	Writing - Original Draft	YES
4163998	25224620	MLN	5	equally contributed to the manuscript with inputs on the stakeholder consultation from EM	equally contributed to the manuscript with inputs on the stakeholder consultation from EM	-	-	NO
4163998	25224620	RK	5	equally contributed to the manuscript with inputs on the stakeholder consultation from EM	equally contributed to the manuscript with inputs on the stakeholder consultation from EM	-	-	NO
4163998	25224620	TF	5	equally contributed to the manuscript with inputs on the stakeholder consultation from EM	equally contributed to the manuscript with inputs on the stakeholder consultation from EM	-	-	NO
1945021	17610741	All authors	2	contributed collection of data and approved the final manuscript	contributed collection of data and approved the final manuscript	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Resources|Writing - Review & Editing	YES
1945021	17610741	MS	2	conceived of the study, and participated in its design and coordination, and performed the first draft of the manuscript	conceived of the study, and participated in its design and coordination, and performed the first draft of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Project administration|Writing - Original Draft	YES
4438938	25772370	C.T.Y.C.	2	contributed equally to this work	contributed equally to this work	-	-	NO
4438938	25772370	W.D.	2	contributed equally to this work	contributed equally to this work	-	-	NO
5103609	27829362	DK	PLoS52	developed the castin software|analyzed the data|wrote the paper	developed the castin software	Contributed reagents/materials/analysis tools	Software	YES
5103609	27829362	DK	PLoS52	developed the castin software|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5103609	27829362	DK	PLoS52	developed the castin software|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5103609	27829362	HA	PLoS52	contributed to the data generation|critically read the manuscript and discussed the results	contributed to the data generation	-	-	NO
5103609	27829362	HA	PLoS52	contributed to the data generation|critically read the manuscript and discussed the results	critically read the manuscript and discussed the results	-	-	NO
5103609	27829362	HK	PLoS52	performed histological analysis	performed histological analysis	Performed the experiments	Investigation	YES
5103609	27829362	KT	PLoS52	contributed to the data generation	contributed to the data generation	-	-	NO
5103609	27829362	MF	PLoS52	critically read the manuscript and discussed the results	critically read the manuscript and discussed the results	-	-	NO
5103609	27829362	MT	PLoS52	contributed to the manual curation of the database	contributed to the manual curation of the database	Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Resources|Software	YES
5103609	27829362	RSato	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5103609	27829362	RSuzuki	PLoS52	developed the castin software	developed the castin software	Contributed reagents/materials/analysis tools	Software	YES
5103609	27829362	SI	PLoS52	conceived and designed the experiments|performed the experiments|contributed to the manual curation of the database|critically read the manuscript and discussed the results	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5103609	27829362	SI	PLoS52	conceived and designed the experiments|performed the experiments|contributed to the manual curation of the database|critically read the manuscript and discussed the results	performed the experiments	Performed the experiments	Investigation	YES
5103609	27829362	SI	PLoS52	conceived and designed the experiments|performed the experiments|contributed to the manual curation of the database|critically read the manuscript and discussed the results	contributed to the manual curation of the database	Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Resources|Software	YES
5103609	27829362	SI	PLoS52	conceived and designed the experiments|performed the experiments|contributed to the manual curation of the database|critically read the manuscript and discussed the results	critically read the manuscript and discussed the results	-	-	NO
5103609	27829362	SY	PLoS52	contributed to the data generation	contributed to the data generation	-	-	NO
5103609	27829362	TI	PLoS52	performed the experiments|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5103609	27829362	TI	PLoS52	performed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4442410	26078964	Bo Peng	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
4442410	26078964	Chunya Bu	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|contributed reagents/materials/analysis tools|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4442410	26078964	Chunya Bu	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|contributed reagents/materials/analysis tools|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
4442410	26078964	Chunya Bu	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|contributed reagents/materials/analysis tools|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
4442410	26078964	Chunya Bu	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|contributed reagents/materials/analysis tools|wrote the paper	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4442410	26078964	Chunya Bu	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|contributed reagents/materials/analysis tools|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4442410	26078964	Guanglu Shia	PLoS52	contributed reagents/materials/analysis tools	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4442410	26078964	Jingyu Han	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
4442410	26078964	Jinling Li	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4442410	26078964	Jinling Li	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
4442410	26078964	Jinling Li	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
4442410	26078964	Pin Gao	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
4442410	26078964	Xiao-Qin Wang	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
4442410	26078964	Younian Wang	PLoS52	contributed reagents/materials/analysis tools	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2789748	19939258	IH	2	have been involved in drafting the manuscript or revising it critically for publication|provided supervision for the project	have been involved in drafting the manuscript or revising it critically for publication	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
2789748	19939258	IH	2	have been involved in drafting the manuscript or revising it critically for publication|provided supervision for the project	provided supervision for the project	-	Supervision	YES
2789748	19939258	JZ	2	helped with sequence data analysis	helped with sequence data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
2789748	19939258	OW	2	assisted with virus culture from stocks	assisted with virus culture from stocks	Performed the experiments	Investigation	YES
2789748	19939258	PN	2	provided the viruses for the work|have been involved in drafting the manuscript or revising it critically for publication	provided the viruses for the work	Contributed reagents/materials/analysis tools	Resources	YES
2789748	19939258	PN	2	provided the viruses for the work|have been involved in drafting the manuscript or revising it critically for publication	have been involved in drafting the manuscript or revising it critically for publication	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
2789748	19939258	SB	2	provided the viruses for the work	provided the viruses for the work	Contributed reagents/materials/analysis tools	Resources	YES
2789748	19939258	SL	2	assisted with virus culture from stocks	assisted with virus culture from stocks	Performed the experiments	Investigation	YES
2789748	19939258	VR	2	have made substantial contributions to conception, design, analysis and interpretation of data	have made substantial contributions to conception, design, analysis and interpretation of data	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Resources	YES
2789748	19939258	XW	2	with tissue culture work	with tissue culture work	Performed the experiments	Investigation	YES
4401549	25884949	AC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401549	25884949	AC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401549	25884949	AC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401549	25884949	AC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401549	25884949	ACC	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401549	25884949	ACC	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401549	25884949	BL	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401549	25884949	BL	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401549	25884949	CLW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401549	25884949	CLW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401549	25884949	CM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401549	25884949	CM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401549	25884949	CM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401549	25884949	DS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401549	25884949	DS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401549	25884949	EP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401549	25884949	EP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401549	25884949	EP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401549	25884949	FRA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401549	25884949	FRA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401549	25884949	FRA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401549	25884949	FRA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401549	25884949	JH	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401549	25884949	JH	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401549	25884949	JPR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401549	25884949	JPR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401549	25884949	JPR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401549	25884949	JS	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401549	25884949	KJK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401549	25884949	KJK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401549	25884949	KJK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401549	25884949	KJK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401549	25884949	LDC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401549	25884949	LDC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401549	25884949	LDC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401549	25884949	MST	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401549	25884949	MST	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401549	25884949	MST	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401549	25884949	MW	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4401549	25884949	MW	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401549	25884949	NP	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4401549	25884949	NP	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401549	25884949	SA	PLoS5	Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Wrote the paper|Review cytogenetic/molecular data and assign cytogenetic risk groups	Analyzed the data	Analyzed the data	Formal analysis	YES
4401549	25884949	SA	PLoS5	Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Wrote the paper|Review cytogenetic/molecular data and assign cytogenetic risk groups	Analyzed the data	Analyzed the data	Formal analysis	YES
4401549	25884949	SA	PLoS5	Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Wrote the paper|Review cytogenetic/molecular data and assign cytogenetic risk groups	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401549	25884949	SA	PLoS5	Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Wrote the paper|Review cytogenetic/molecular data and assign cytogenetic risk groups	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401549	25884949	SA	PLoS5	Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Wrote the paper|Review cytogenetic/molecular data and assign cytogenetic risk groups	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401549	25884949	SA	PLoS5	Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Wrote the paper|Review cytogenetic/molecular data and assign cytogenetic risk groups	Review cytogenetic/molecular data and assign cytogenetic risk groups	Performed the experiments	Investigation	YES
4401549	25884949	SP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401549	25884949	SP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401549	25884949	SP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401549	25884949	UG	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401549	25884949	ZS	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
6055760	29682728	FAK	2	collected data and managed the study with support and input from all other authors	collected data and managed the study with support and input from all other authors	Performed the experiments	Investigation|Project administration	YES
6055760	29682728	JSB	2	collected data and managed the study with support and input from all other authors	collected data and managed the study with support and input from all other authors	Performed the experiments	Investigation|Project administration	YES
6055760	29682728	JV	2	wrote the first draft of the manuscript, which was reviewed, modified and approved by all other authors	wrote the first draft of the manuscript, which was reviewed, modified and approved by all other authors	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6055760	29682728	LMvdP	2	collected data and managed the study with support and input from all other authors	collected data and managed the study with support and input from all other authors	Performed the experiments	Investigation|Project administration	YES
6055760	29682728	MJHAK	2	designed the study|wrote the first draft of the manuscript, which was reviewed, modified and approved by all other authors	designed the study	Conceived and designed the experiments	Methodology	YES
6055760	29682728	MJHAK	2	designed the study|wrote the first draft of the manuscript, which was reviewed, modified and approved by all other authors	wrote the first draft of the manuscript, which was reviewed, modified and approved by all other authors	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6055760	29682728	MVH	2	collected data and managed the study with support and input from all other authors	collected data and managed the study with support and input from all other authors	Performed the experiments	Investigation|Project administration	YES
6055760	29682728	S.S.	2	collected data and managed the study with support and input from all other authors|analysed the data, which were interpreted by all other authors|wrote the first draft of the manuscript, which was reviewed, modified and approved by all other authors	collected data and managed the study with support and input from all other authors	Performed the experiments	Investigation|Project administration	YES
6055760	29682728	S.S.	2	collected data and managed the study with support and input from all other authors|analysed the data, which were interpreted by all other authors|wrote the first draft of the manuscript, which was reviewed, modified and approved by all other authors	analysed the data, which were interpreted by all other authors	Analyzed the data	Formal analysis	YES
6055760	29682728	S.S.	2	collected data and managed the study with support and input from all other authors|analysed the data, which were interpreted by all other authors|wrote the first draft of the manuscript, which was reviewed, modified and approved by all other authors	wrote the first draft of the manuscript, which was reviewed, modified and approved by all other authors	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6055760	29682728	SS	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
6055760	29682728	TvG	2	wrote the first draft of the manuscript, which was reviewed, modified and approved by all other authors	wrote the first draft of the manuscript, which was reviewed, modified and approved by all other authors	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6055760	29682728	TvdH	2	collected data and managed the study with support and input from all other authors	collected data and managed the study with support and input from all other authors	Performed the experiments	Investigation|Project administration	YES
5475409	28674543	AT	2	designed methods, carried out laboratory experiments and analyzed the data	designed methods, carried out laboratory experiments and analyzed the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5475409	28674543	All authors	2	have contributed to, seen and approved the manuscript	have contributed to, seen and approved the manuscript	-	-	NO
5475409	28674543	CN	2	co-designed experiments, discussed analyses, interpreted the results, and wrote the paper	co-designed experiments, discussed analyses, interpreted the results, and wrote the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5475409	28674543	DR	2	designed methods, carried out laboratory experiments and analyzed the data	designed methods, carried out laboratory experiments and analyzed the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5475409	28674543	EP	2	designed methods, carried out laboratory experiments and analyzed the data	designed methods, carried out laboratory experiments and analyzed the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5475409	28674543	GL	2	defined the research theme and obtained funding	defined the research theme and obtained funding	-	Funding acquisition	YES
5475409	28674543	LC	2	designed methods, carried out laboratory experiments and analyzed the data	designed methods, carried out laboratory experiments and analyzed the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5475409	28674543	LG	2	co-designed experiments, discussed analyses, interpreted the results, and wrote the paper	co-designed experiments, discussed analyses, interpreted the results, and wrote the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5475409	28674543	ML	2	designed methods, carried out laboratory experiments and analyzed the data	designed methods, carried out laboratory experiments and analyzed the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5475409	28674543	MT	2	designed methods, carried out laboratory experiments and analyzed the data	designed methods, carried out laboratory experiments and analyzed the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5475409	28674543	PV	2	co-designed experiments, discussed analyses, interpreted the results, and wrote the paper	co-designed experiments, discussed analyses, interpreted the results, and wrote the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5475409	28674543	RM	2	defined the research theme and obtained funding	defined the research theme and obtained funding	-	Funding acquisition	YES
4164000	25224617	All authors	2	have reviewed and approved the final manuscript	have reviewed and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4164000	25224617	EET	2	provided extensive comments and edits	provided extensive comments and edits	Wrote the paper	Writing - Review & Editing	YES
4164000	25224617	KMM	2	drafted the initial manuscript|provided extensive comments and edits	drafted the initial manuscript	Wrote the paper	Writing - Original Draft	YES
4164000	25224617	KMM	2	drafted the initial manuscript|provided extensive comments and edits	provided extensive comments and edits	Wrote the paper	Writing - Review & Editing	YES
4164000	25224617	KRA	2	provided extensive comments and edits	provided extensive comments and edits	Wrote the paper	Writing - Review & Editing	YES
2794860	19954551	AC	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
2794860	19954551	ACB	2	is the principal investigator responsible for designing the work and writing the manuscript	is the principal investigator responsible for designing the work and writing the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Funding acquisition|Writing - Original Draft	YES
2794860	19954551	AW	2	were responsible for providing the blood samples and their clinical characteristics	were responsible for providing the blood samples and their clinical characteristics	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
2794860	19954551	NG	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
2794860	19954551	SD	2	were responsible for providing the blood samples and their clinical characteristics	were responsible for providing the blood samples and their clinical characteristics	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
2794860	19954551	UN	2	carried out the experiments|contributed equally to this work	carried out the experiments	Performed the experiments	Investigation	YES
2794860	19954551	UN	2	carried out the experiments|contributed equally to this work	contributed equally to this work	-	-	NO
2794860	19954551	VGR	2	were responsible for providing the blood samples and their clinical characteristics	were responsible for providing the blood samples and their clinical characteristics	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
2794860	19954551	VKS	2	were responsible for providing the blood samples and their clinical characteristics	were responsible for providing the blood samples and their clinical characteristics	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
2794860	19954551	VS	2	carried out the experiments|contributed equally to this work	carried out the experiments	Performed the experiments	Investigation	YES
2794860	19954551	VS	2	carried out the experiments|contributed equally to this work	contributed equally to this work	-	-	NO
5103610	27829353	CDD	2	was responsible for fiber property measurement	was responsible for fiber property measurement	Performed the experiments	Investigation	YES
5103610	27829353	DCJ	2	edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5103610	27829353	DDD	2	provided ncvt cultivar phenotypic data	provided ncvt cultivar phenotypic data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5103610	27829353	DDF	2	conceived the research and revised the manuscript	conceived the research and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5103610	27829353	DJH	2	grew the parent lines and isolated rnas	grew the parent lines and isolated rnas	Performed the experiments	Investigation	YES
5103610	27829353	GNT	2	analyzed wgs and rna seq data, and helped identify mutations in genes	analyzed wgs and rna seq data, and helped identify mutations in genes	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5103610	27829353	MSI	2	coordinated experiments	coordinated experiments	-	Project administration	YES
2186329	17996077	All	2	experiments were conducted at the institute of sports medicine, free university berlin	experiments were conducted at the institute of sports medicine, free university berlin	Performed the experiments	Investigation	YES
2186329	17996077	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
2186329	17996077	MDJ	2	conducted the experiments, analyzed the data and helped to draft the manuscript	conducted the experiments, analyzed the data and helped to draft the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
2186329	17996077	RB	2	designed and coordinated the study, helped to analyze the data and drafted the manuscript	designed and coordinated the study, helped to analyze the data and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Project administration|Writing - Original Draft	YES
2186329	17996077	RML	2	helped to develop the study design and to draft the manuscript	helped to develop the study design and to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
2805683	20030841	KR	2	participated in the design of the study and draft the manuscript	participated in the design of the study and draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
2805683	20030841	SK	2	participated in the design of the study and draft the manuscript	participated in the design of the study and draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
2805683	20030841	SN	2	participated in the design of the study	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
2805683	20030841	SS	2	participated in the design of the study and draft the manuscript	participated in the design of the study and draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
2805683	20030841	ST	2	participated in the design of the study and draft the manuscript	participated in the design of the study and draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
2805683	20030841	WA	2	participated in the design of the study and draft the manuscript	participated in the design of the study and draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
2805683	20030841	WM	2	participated in the design of the study, statistical analysis and draft the manuscript	participated in the design of the study, statistical analysis and draft the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
2805683	20030841	WP	2	participated in the design of the study and draft the manuscript	participated in the design of the study and draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4401550	25884493	AH	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401550	25884493	AH	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401550	25884493	AR	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401550	25884493	AR	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401550	25884493	GEE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401550	25884493	GEE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401550	25884493	GEE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401550	25884493	GEE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401550	25884493	GEE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401550	25884493	LB	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401550	25884493	LB	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401550	25884493	ME	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401550	25884493	ME	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401550	25884493	PB	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401550	25884493	PB	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401550	25884493	SB	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401550	25884493	SB	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401550	25884493	SZ	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401550	25884493	SZ	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401550	25884493	SZ	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401550	25884493	VF	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401550	25884493	VF	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401550	25884493	VS	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401550	25884493	VS	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401550	25884493	ZD	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401550	25884493	ZD	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401550	25884493	ZD	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401550	25884493	ZK	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401550	25884493	ZK	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4164013	25224614	NS	2	all contributed to the conceptualization, analysis and writing of the manuscript	all contributed to the conceptualization, analysis and writing of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4164013	25224614	QA-K	2	all contributed to the conceptualization, analysis and writing of the manuscript	all contributed to the conceptualization, analysis and writing of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4164013	25224614	TDM	2	all contributed to the conceptualization, analysis and writing of the manuscript	all contributed to the conceptualization, analysis and writing of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5476734	28676809	CF	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5476734	28676809	JC	PLoS52	designed research|performed research|analyzed data|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
5476734	28676809	JC	PLoS52	designed research|performed research|analyzed data|wrote the paper	performed research	Performed the experiments	Investigation	YES
5476734	28676809	JC	PLoS52	designed research|performed research|analyzed data|wrote the paper	analyzed data	Analyzed the data	Formal analysis	YES
5476734	28676809	JC	PLoS52	designed research|performed research|analyzed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5476734	28676809	JW	PLoS52	analyzed data|wrote the paper	analyzed data	Analyzed the data	Formal analysis	YES
5476734	28676809	JW	PLoS52	analyzed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5476734	28676809	YH	PLoS52	performed research|analyzed data|wrote the paper	performed research	Performed the experiments	Investigation	YES
5476734	28676809	YH	PLoS52	performed research|analyzed data|wrote the paper	analyzed data	Analyzed the data	Formal analysis	YES
5476734	28676809	YH	PLoS52	performed research|analyzed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5476734	28676809	YY	PLoS52	designed research|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
5476734	28676809	YY	PLoS52	designed research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
2254413	18194584	AH	2	examined the training method	examined the training method	Performed the experiments	-	YES
2254413	18194584	CU	2	also performed measurement and evaluation of nirs data	also performed measurement and evaluation of nirs data	Performed the experiments	Investigation	YES
2254413	18194584	FO	2	also performed measurement and evaluation of nirs data	also performed measurement and evaluation of nirs data	Performed the experiments	Investigation	YES
2254413	18194584	KE	2	performed measurement and evaluation of nirs data	performed measurement and evaluation of nirs data	Performed the experiments	Investigation	YES
2254413	18194584	KS	2	also performed measurement and evaluation of nirs data	also performed measurement and evaluation of nirs data	Performed the experiments	Investigation	YES
2254413	18194584	KY	2	also performed measurement and evaluation of nirs data	also performed measurement and evaluation of nirs data	Performed the experiments	Investigation	YES
2254413	18194584	MM	2	performed selection and medical checks of the experiment subjects as well as the measurement and evaluation of nirs data	performed selection and medical checks of the experiment subjects as well as the measurement and evaluation of nirs data	Performed the experiments	Data curation|Investigation	YES
2254413	18194584	NM	2	performed selection and medical checks of the experiment subjects	performed selection and medical checks of the experiment subjects	Performed the experiments	Investigation	YES
2254413	18194584	SI	2	also performed measurement and evaluation of nirs data	also performed measurement and evaluation of nirs data	Performed the experiments	Investigation	YES
2254413	18194584	TH	2	served as the general administrator for the experiment and performed the cast immobilization process	served as the general administrator for the experiment and performed the cast immobilization process	Performed the experiments	Investigation	YES
2254413	18194584	TK	2	examined the training method	examined the training method	Performed the experiments	-	YES
2254413	18194584	TO	2	performed selection and medical checks of the experiment subjects	performed selection and medical checks of the experiment subjects	Performed the experiments	Investigation	YES
2254413	18194584	YK	2	performed measurement and evaluation of nirs data	performed measurement and evaluation of nirs data	Performed the experiments	Investigation	YES
5106776	27835957	APS	PLoS5	Conceived and designed the experiments|Contributed material/reagents/analysis tools|Drafted the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5106776	27835957	APS	PLoS5	Conceived and designed the experiments|Contributed material/reagents/analysis tools|Drafted the manuscript	Contributed material/reagents/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5106776	27835957	APS	PLoS5	Conceived and designed the experiments|Contributed material/reagents/analysis tools|Drafted the manuscript	Drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5106776	27835957	BBZV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed material/reagents/analysis tools|Drafted the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5106776	27835957	BBZV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed material/reagents/analysis tools|Drafted the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
5106776	27835957	BBZV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed material/reagents/analysis tools|Drafted the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
5106776	27835957	BBZV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed material/reagents/analysis tools|Drafted the manuscript	Contributed material/reagents/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5106776	27835957	BBZV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed material/reagents/analysis tools|Drafted the manuscript	Drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5106776	27835957	CBV	PLoS5	Conceived and designed the experiments|Contributed material/reagents/analysis tools|Drafted the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5106776	27835957	CBV	PLoS5	Conceived and designed the experiments|Contributed material/reagents/analysis tools|Drafted the manuscript	Contributed material/reagents/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5106776	27835957	CBV	PLoS5	Conceived and designed the experiments|Contributed material/reagents/analysis tools|Drafted the manuscript	Drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5106776	27835957	CCS	PLoS5	Performed the experiments|Analyzed the data|Contributed material/reagents/analysis tools|Drafted the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
5106776	27835957	CCS	PLoS5	Performed the experiments|Analyzed the data|Contributed material/reagents/analysis tools|Drafted the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
5106776	27835957	CCS	PLoS5	Performed the experiments|Analyzed the data|Contributed material/reagents/analysis tools|Drafted the manuscript	Contributed material/reagents/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5106776	27835957	CCS	PLoS5	Performed the experiments|Analyzed the data|Contributed material/reagents/analysis tools|Drafted the manuscript	Drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5106776	27835957	FAO	PLoS5	Performed the experiments|Analyzed the data|Contributed material/reagents/analysis tools|Drafted the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
5106776	27835957	FAO	PLoS5	Performed the experiments|Analyzed the data|Contributed material/reagents/analysis tools|Drafted the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
5106776	27835957	FAO	PLoS5	Performed the experiments|Analyzed the data|Contributed material/reagents/analysis tools|Drafted the manuscript	Contributed material/reagents/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5106776	27835957	FAO	PLoS5	Performed the experiments|Analyzed the data|Contributed material/reagents/analysis tools|Drafted the manuscript	Drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5106776	27835957	GTS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed material/reagents/analysis tools|Drafted the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5106776	27835957	GTS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed material/reagents/analysis tools|Drafted the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
5106776	27835957	GTS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed material/reagents/analysis tools|Drafted the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
5106776	27835957	GTS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed material/reagents/analysis tools|Drafted the manuscript	Contributed material/reagents/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5106776	27835957	GTS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed material/reagents/analysis tools|Drafted the manuscript	Drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
2809072	20028544	All authors	2	contributed to interpretation of the data and provided critical review and approval of the manuscript	contributed to interpretation of the data and provided critical review and approval of the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
2809072	20028544	BS	2	carried out the statistical analyses	carried out the statistical analyses	Analyzed the data	Formal analysis	YES
2809072	20028544	IO	2	designed the study and protocol, conducted the study, and collected data	designed the study and protocol, conducted the study, and collected data	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4164014	25224616	CM	2	contributed to study design and data collection, and revised manuscript critically|contributed to study design, data collection, development of research instruments and interpretation of data, and revised manuscript critically	contributed to study design and data collection, and revised manuscript critically	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Methodology|Resources|Writing - Review & Editing	YES
4164014	25224616	CM	2	contributed to study design and data collection, and revised manuscript critically|contributed to study design, data collection, development of research instruments and interpretation of data, and revised manuscript critically	contributed to study design, data collection, development of research instruments and interpretation of data, and revised manuscript critically	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
4164014	25224616	EE	2	principal investigator, contributed to study design, development of research instruments, acquisition of data, data analysis, interpretation of data and manuscript writing	principal investigator, contributed to study design, development of research instruments, acquisition of data, data analysis, interpretation of data and manuscript writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Funding acquisition|Investigation|Methodology|Resources|Writing - Original Draft	YES
4164014	25224616	ET	2	conceptualized and designed study, provided input on data collection, co-developed research instruments, contributed to data analysis and provided critical input into manuscript	conceptualized and designed study, provided input on data collection, co-developed research instruments, contributed to data analysis and provided critical input into manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
4164014	25224616	JK	2	contributed to study design, data collection and revised manuscript critically	contributed to study design, data collection and revised manuscript critically	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Methodology|Resources|Writing - Review & Editing	YES
4164014	25224616	JS	2	contributed to study design, data collection, development of research instruments and interpretation of data, and revised manuscript critically	contributed to study design, data collection, development of research instruments and interpretation of data, and revised manuscript critically	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
4164014	25224616	KB	2	analysed and interpreted study data, and revised manuscript critically	analysed and interpreted study data, and revised manuscript critically	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4164014	25224616	NM	2	lead writer of the manuscript, contributed to study design, co-developed research instruments and contributed to interpretation of data	lead writer of the manuscript, contributed to study design, co-developed research instruments and contributed to interpretation of data	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Original Draft	YES
4139179	25068927	All authors	2	have given approval to the final version of the manuscript	have given approval to the final version of the manuscript	-	-	NO
2265701	18226247	CMD	2	conducted the experiments, performed initial data analysis, and drafted the manuscript	conducted the experiments, performed initial data analysis, and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
2265701	18226247	KKM	2	conceived of the study and participated in its design and coordination, and in writing the manuscript	conceived of the study and participated in its design and coordination, and in writing the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
2265701	18226247	MEC	2	participated in the preparation of the study design and in writing the manuscript	participated in the preparation of the study design and in writing the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5476739	28676815	GZ	PLoS52	conceived with the study|conducted most of the research|analyzed the data|wrote the manuscript	conceived with the study	Conceived and designed the experiments	Conceptualization	YES
5476739	28676815	GZ	PLoS52	conceived with the study|conducted most of the research|analyzed the data|wrote the manuscript	conducted most of the research	Performed the experiments	Investigation	YES
5476739	28676815	GZ	PLoS52	conceived with the study|conducted most of the research|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5476739	28676815	GZ	PLoS52	conceived with the study|conducted most of the research|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5476739	28676815	HW	PLoS52	conceived with the study|analyzed the data|wrote the manuscript|supervised the project	conceived with the study	Conceived and designed the experiments	Conceptualization	YES
5476739	28676815	HW	PLoS52	conceived with the study|analyzed the data|wrote the manuscript|supervised the project	analyzed the data	Analyzed the data	Formal analysis	YES
5476739	28676815	HW	PLoS52	conceived with the study|analyzed the data|wrote the manuscript|supervised the project	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5476739	28676815	HW	PLoS52	conceived with the study|analyzed the data|wrote the manuscript|supervised the project	supervised the project	-	Supervision	YES
5476739	28676815	QZ	PLoS52	conducted most of the research|analyzed the data	conducted most of the research	Performed the experiments	Investigation	YES
5476739	28676815	QZ	PLoS52	conducted most of the research|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5476739	28676815	YLi	PLoS52	conducted most of the research	conducted most of the research	Performed the experiments	Investigation	YES
5476739	28676815	YLiu	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
4401551	25886619	FW	PLoS5	Contributed reagents/materials/analysis tools|Radiation equipment setting and operation	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401551	25886619	FW	PLoS5	Contributed reagents/materials/analysis tools|Radiation equipment setting and operation	Radiation equipment setting and operation	Performed the experiments	Investigation	YES
4401551	25886619	HZW	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401551	25886619	JH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401551	25886619	JH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401551	25886619	JH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401551	25886619	JH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401551	25886619	PKNY	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401551	25886619	PZK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401551	25886619	WH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401551	25886619	WH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401551	25886619	WH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2821359	20051116	JB	2	conceived the study and wrote the manuscript	conceived the study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
2821359	20051116	MC	2	performed patient follow up and reviewed the manuscript	performed patient follow up and reviewed the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
2821359	20051116	MM	2	performed the data analysis and reviewed the manuscript	performed the data analysis and reviewed the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
2821359	20051116	VL	2	performed data abstraction and manuscript review	performed data abstraction and manuscript review	Wrote the paper	Writing - Review & Editing	YES
5106785	27835943	GJ	2	carried out biochemical experiments and analyzed the data|wrote the manuscript	carried out biochemical experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5106785	27835943	GJ	2	carried out biochemical experiments and analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5106785	27835943	YHL	2	carried out biochemical experiments and analyzed the data	carried out biochemical experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5106785	27835943	YKK	2	carried out biochemical experiments and analyzed the data|performed bioinformatics analyses|wrote the manuscript	carried out biochemical experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5106785	27835943	YKK	2	carried out biochemical experiments and analyzed the data|performed bioinformatics analyses|wrote the manuscript	performed bioinformatics analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5106785	27835943	YKK	2	carried out biochemical experiments and analyzed the data|performed bioinformatics analyses|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
2265702	18226263	AO	2	participated in the sequence alignment and draft the manuscript	participated in the sequence alignment and draft the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
2265702	18226263	AZ	2	participated in the design of the study and performed the statistical analysis	participated in the design of the study and performed the statistical analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
2265702	18226263	YM	2	conceived of the study and in its design and coordination and helped to draft the manuscript	conceived of the study and in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
4401553	25884924	LK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Obtained funding	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401553	25884924	LK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Obtained funding	Performed the experiments	Performed the experiments	Investigation	YES
4401553	25884924	LK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Obtained funding	Analyzed the data	Analyzed the data	Formal analysis	YES
4401553	25884924	LK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Obtained funding	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401553	25884924	LK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Obtained funding	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401553	25884924	LK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Obtained funding	Obtained funding	-	Funding acquisition	YES
4401553	25884924	ML	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Obtained funding	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401553	25884924	ML	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Obtained funding	Analyzed the data	Analyzed the data	Formal analysis	YES
4401553	25884924	ML	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Obtained funding	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401553	25884924	ML	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Obtained funding	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401553	25884924	ML	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Obtained funding	Obtained funding	-	Funding acquisition	YES
5476740	28676818	HZ	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
5476740	28676818	JG	PLoS52	designed the research|performed research|analyzed the data|wrote the paper	designed the research	Conceived and designed the experiments	Methodology	YES
5476740	28676818	JG	PLoS52	designed the research|performed research|analyzed the data|wrote the paper	performed research	Performed the experiments	Investigation	YES
5476740	28676818	JG	PLoS52	designed the research|performed research|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5476740	28676818	JG	PLoS52	designed the research|performed research|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5476740	28676818	JY	PLoS52	designed the research|analyzed the data|wrote the paper	designed the research	Conceived and designed the experiments	Methodology	YES
5476740	28676818	JY	PLoS52	designed the research|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5476740	28676818	JY	PLoS52	designed the research|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5476740	28676818	The authors	PLoS52	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	Performed the experiments	Investigation	YES
5476740	28676818	YC	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
5476740	28676818	ZL	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
5476740	28676818	ZW	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
5476740	28676818	ZZ	PLoS52	performed research|analyzed the data|wrote the paper	performed research	Performed the experiments	Investigation	YES
5476740	28676818	ZZ	PLoS52	performed research|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5476740	28676818	ZZ	PLoS52	performed research|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4164016	25224613	AC	2	identified the research topic, participated in the qualitative data analysis and wrote the manuscript	identified the research topic, participated in the qualitative data analysis and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4164016	25224613	All authors	2	made substantial contributions to the conception, acquisition, analysis or interpretation of the data	made substantial contributions to the conception, acquisition, analysis or interpretation of the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
4164016	25224613	JH	2	led the qualitative data analysis and contributed to the development of the manuscript	led the qualitative data analysis and contributed to the development of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4164016	25224613	JO	2	were actively engaged in the collection of the data, participated in a data interpretation meeting and provided critical insight into content of the manuscript	were actively engaged in the collection of the data, participated in a data interpretation meeting and provided critical insight into content of the manuscript	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4164016	25224613	JS	2	were actively engaged in the collection of the data, participated in a data interpretation meeting and provided critical insight into content of the manuscript	were actively engaged in the collection of the data, participated in a data interpretation meeting and provided critical insight into content of the manuscript	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4164016	25224613	KAgot	2	were actively engaged in the collection of the data, participated in a data interpretation meeting and provided critical insight into content of the manuscript	were actively engaged in the collection of the data, participated in a data interpretation meeting and provided critical insight into content of the manuscript	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4164016	25224613	KAhmed	2	were actively engaged in the collection of the data, participated in a data interpretation meeting and provided critical insight into content of the manuscript	were actively engaged in the collection of the data, participated in a data interpretation meeting and provided critical insight into content of the manuscript	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4164016	25224613	KM	2	led the qualitative data analysis and contributed to the development of the manuscript	led the qualitative data analysis and contributed to the development of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4164016	25224613	MW	2	conducted the descriptive statistics and provided beneficial feedback on draft versions	conducted the descriptive statistics and provided beneficial feedback on draft versions	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
2288598	18304350	ASF	2	all recruited subjects and revised the manuscript	all recruited subjects and revised the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
2288598	18304350	AWG	2	designed the study, assisted with both statistical analyses and the interpretation of it, and also drafted and revised the manuscript	designed the study, assisted with both statistical analyses and the interpretation of it, and also drafted and revised the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
2288598	18304350	CF	2	acquired the data, recruited subjects, worked on the statistical analyses of the manuscript and the interpretation of the data, as well as drafting and revising the manuscript	acquired the data, recruited subjects, worked on the statistical analyses of the manuscript and the interpretation of the data, as well as drafting and revising the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
2288598	18304350	KJN	2	all recruited subjects and revised the manuscript	all recruited subjects and revised the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
2288598	18304350	LSA	2	all recruited subjects and revised the manuscript	all recruited subjects and revised the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
2834596	20804564	CV	2	designed the initial study and were involved in the coordination, and interpretation of the results	designed the initial study and were involved in the coordination, and interpretation of the results	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology|Project administration	YES
2834596	20804564	DV	2	are consortium members who contributed in the design of the study, the collection of samples, and discussion on interpretation of results	are consortium members who contributed in the design of the study, the collection of samples, and discussion on interpretation of results	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Formal analysis|Investigation|Methodology|Resources	YES
2834596	20804564	EF	2	are consortium members who contributed in the design of the study, the collection of samples, and discussion on interpretation of results	are consortium members who contributed in the design of the study, the collection of samples, and discussion on interpretation of results	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Formal analysis|Investigation|Methodology|Resources	YES
2834596	20804564	ER	2	participated in the design of the assay, the performance of the experiments and interpretation of the results	participated in the design of the assay, the performance of the experiments and interpretation of the results	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
2834596	20804564	HVM	2	participated in the design of the assay, the performance of the experiments and interpretation of the results	participated in the design of the assay, the performance of the experiments and interpretation of the results	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
2834596	20804564	IVDB	2	participated in the design of the assay, the performance of the experiments and interpretation of the results	participated in the design of the assay, the performance of the experiments and interpretation of the results	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
2834596	20804564	KF	2	are consortium members who contributed in the design of the study, the collection of samples, and discussion on interpretation of results	are consortium members who contributed in the design of the study, the collection of samples, and discussion on interpretation of results	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Formal analysis|Investigation|Methodology|Resources	YES
2834596	20804564	KK	2	are consortium members who contributed in the design of the study, the collection of samples, and discussion on interpretation of results	are consortium members who contributed in the design of the study, the collection of samples, and discussion on interpretation of results	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Formal analysis|Investigation|Methodology|Resources	YES
2834596	20804564	KT	2	participated in the design of the assay, the performance of the experiments and interpretation of the results	participated in the design of the assay, the performance of the experiments and interpretation of the results	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
2834596	20804564	KVB	2	participated in the design of the assay, the performance of the experiments and interpretation of the results	participated in the design of the assay, the performance of the experiments and interpretation of the results	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
2834596	20804564	LJS	2	designed the initial study and were involved in the coordination, and interpretation of the results	designed the initial study and were involved in the coordination, and interpretation of the results	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology|Project administration	YES
2834596	20804564	LVDK	2	designed the initial study and were involved in the coordination, and interpretation of the results	designed the initial study and were involved in the coordination, and interpretation of the results	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology|Project administration	YES
2834596	20804564	MM	2	are consortium members who contributed in the design of the study, the collection of samples, and discussion on interpretation of results	are consortium members who contributed in the design of the study, the collection of samples, and discussion on interpretation of results	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Formal analysis|Investigation|Methodology|Resources	YES
2834596	20804564	SDW	2	are consortium members who contributed in the design of the study, the collection of samples, and discussion on interpretation of results	are consortium members who contributed in the design of the study, the collection of samples, and discussion on interpretation of results	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Formal analysis|Investigation|Methodology|Resources	YES
2834596	20804564	VVE	2	participated in the design of the assay, the performance of the experiments and interpretation of the results	participated in the design of the assay, the performance of the experiments and interpretation of the results	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
2834596	20804564	WM	2	participated in the design of the assay, the performance of the experiments and interpretation of the results	participated in the design of the assay, the performance of the experiments and interpretation of the results	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
6175474	30004123	D. Moertl	2	were involved in designing the study	were involved in designing the study	Conceived and designed the experiments	Methodology	YES
6175474	30004123	G. Goliasch	2	provided critical revisions to the manuscript draft	provided critical revisions to the manuscript draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6175474	30004123	I. Lang	2	provided critical revisions to the manuscript draft	provided critical revisions to the manuscript draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6175474	30004123	K. Distelmaier	2	were involved in designing the study	were involved in designing the study	Conceived and designed the experiments	Methodology	YES
6175474	30004123	KD	2	analysed and interpreted the data|drafted the manuscript	analysed and interpreted the data	Analyzed the data	Formal analysis	YES
6175474	30004123	KD	2	analysed and interpreted the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
6175474	30004123	M. Huelsmann	2	were involved in designing the study	were involved in designing the study	Conceived and designed the experiments	Methodology	YES
6175474	30004123	MH	2	analysed and interpreted the data	analysed and interpreted the data	Analyzed the data	Formal analysis	YES
6175474	30004123	N. Pavo	2	provided critical revisions to the manuscript draft	provided critical revisions to the manuscript draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6175474	30004123	R. Berger	2	were involved in designing the study	were involved in designing the study	Conceived and designed the experiments	Methodology	YES
6175474	30004123	R. Wurm	2	were involved in designing the study	were involved in designing the study	Conceived and designed the experiments	Methodology	YES
6175474	30004123	RW	2	analysed and interpreted the data|drafted the manuscript	analysed and interpreted the data	Analyzed the data	Formal analysis	YES
6175474	30004123	RW	2	analysed and interpreted the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5106808	27835940	DAP	2	designed the overall research project and drafted the manuscript, tables and figures	designed the overall research project and drafted the manuscript, tables and figures	Conceived and designed the experiments|Wrote the paper	Methodology|Visualization|Writing - Original Draft	YES
5106808	27835940	GB	2	prepared next-generation sequencing libraries and performed the sequencing|who died unexpectedly during the course of the study, read and approved the final manuscript	prepared next-generation sequencing libraries and performed the sequencing	Performed the experiments	Investigation	YES
5106808	27835940	GB	2	prepared next-generation sequencing libraries and performed the sequencing|who died unexpectedly during the course of the study, read and approved the final manuscript	who died unexpectedly during the course of the study, read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5106808	27835940	JD	2	designed the overall research project and drafted the manuscript, tables and figures	designed the overall research project and drafted the manuscript, tables and figures	Conceived and designed the experiments|Wrote the paper	Methodology|Visualization|Writing - Original Draft	YES
5106808	27835940	JF	2	prepared next-generation sequencing libraries and performed the sequencing	prepared next-generation sequencing libraries and performed the sequencing	Performed the experiments	Investigation	YES
5106808	27835940	JHK	2	designed the overall research project and drafted the manuscript, tables and figures	designed the overall research project and drafted the manuscript, tables and figures	Conceived and designed the experiments|Wrote the paper	Methodology|Visualization|Writing - Original Draft	YES
4401554	25884619	CP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401554	25884619	CP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401554	25884619	CP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401554	25884619	CP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401554	25884619	CP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401554	25884619	FC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401554	25884619	FC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401554	25884619	FC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401554	25884619	FP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401554	25884619	FP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4401554	25884619	FP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4401554	25884619	FP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401554	25884619	GC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4401554	25884619	GC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401554	25884619	MD	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4401554	25884619	MD	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401554	25884619	MP	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4401554	25884619	MP	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401554	25884619	RD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401554	25884619	RD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4401554	25884619	RD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4401554	25884619	RD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401554	25884619	SS	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401554	25884619	SS	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401554	25884619	TO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401554	25884619	TO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4401554	25884619	TO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4401554	25884619	TO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5476748	28676806	BD	2	designed and performed the experiments, and prepared the manuscript	designed and performed the experiments, and prepared the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5476748	28676806	HL	2	modified the manuscript	modified the manuscript	Wrote the paper	Writing - Review & Editing	YES
5476748	28676806	HY	2	performed anther microscopic observation	performed anther microscopic observation	Performed the experiments	Investigation	YES
5476748	28676806	HZ	2	performed starch staining	performed starch staining	Performed the experiments	Investigation	YES
5476748	28676806	JA	2	modified the manuscript	modified the manuscript	Wrote the paper	Writing - Review & Editing	YES
5476748	28676806	ML	2	supervised this project and prepared the manuscript	supervised this project and prepared the manuscript	Wrote the paper	Supervision|Writing - Original Draft	YES
5476748	28676806	MZ	2	measured photosynthetic and transpiration rate	measured photosynthetic and transpiration rate	Performed the experiments	Investigation	YES
5476748	28676806	XZ	2	performed gene expression analysis and prepared the manuscript	performed gene expression analysis and prepared the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5476748	28676806	YQ	2	measured photosynthetic and transpiration rate	measured photosynthetic and transpiration rate	Performed the experiments	Investigation	YES
5476748	28676806	YW	2	performed sugar measurement	performed sugar measurement	Performed the experiments	Investigation	YES
4164017	25224615	CW	2	wrote the manuscript and led the project work discussed in this paper for both trials	wrote the manuscript and led the project work discussed in this paper for both trials	Wrote the paper	Writing - Original Draft	YES
2836271	20180966	All authors	2	fulfill the criteria of authorship and contributed collaboratively to conception and design, analysis and interpretation of data, drafting the article, revising it critically for important intellectual content and final approval of the version to be published	fulfill the criteria of authorship and contributed collaboratively to conception and design, analysis and interpretation of data, drafting the article, revising it critically for important intellectual content and final approval of the version to be published	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Resources|Writing - Original Draft|Writing - Review & Editing	YES
2836271	20180966	BR	2	was a co-investigator and participated in the planning, analysis and writing of the paper	was a co-investigator and participated in the planning, analysis and writing of the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
2836271	20180966	KAJ	2	was principal investigator, designed the study, performed the systematic literature search, developed the markov model, led the analysis, and was lead author for the paper	was principal investigator, designed the study, performed the systematic literature search, developed the markov model, led the analysis, and was lead author for the paper	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Formal analysis|Funding acquisition|Investigation|Methodology|Writing - Original Draft	YES
2836271	20180966	OFN	2	sought funding for the study, contributed to design, planning, analysis and writing of the paper	sought funding for the study, contributed to design, planning, analysis and writing of the paper	Conceived and designed the experiments|Wrote the paper	Funding acquisition|Methodology|Writing - Original Draft	YES
4401557	25886283	CH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401557	25886283	CK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401557	25886283	FM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401557	25886283	HH	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401557	25886283	HQ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401557	25886283	JL	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401557	25886283	PS	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401557	25886283	XC	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401557	25886283	XC	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401557	25886283	YG	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401557	25886283	YZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401557	25886283	ZW	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2845546	20180959	AG	2	assisted in data collection and reviewed the initial and final drafts of the manuscript	assisted in data collection and reviewed the initial and final drafts of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
2845546	20180959	AM	2	assisted in data collection and reviewed the initial and final drafts of the manuscript	assisted in data collection and reviewed the initial and final drafts of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
2845546	20180959	BT	2	was the primary researcher, conceived the study, designed, conducted data analysis and drafted the manuscript for publication	was the primary researcher, conceived the study, designed, conducted data analysis and drafted the manuscript for publication	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
2845546	20180959	FB	2	assisted in data collection and reviewed the initial and final drafts of the manuscript	assisted in data collection and reviewed the initial and final drafts of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
2845546	20180959	FE	2	interpreted the results, and reviewed the initial and final drafts of the manuscript	interpreted the results, and reviewed the initial and final drafts of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
2845546	20180959	US	2	interpreted the results, and reviewed the initial and final drafts of the manuscript	interpreted the results, and reviewed the initial and final drafts of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5476749	28676803	EG	2	assisted with the statistical analysis and description	assisted with the statistical analysis and description	Analyzed the data	Formal analysis	YES
5476749	28676803	HE	2	contributed to the conception and design of the study, to the interpretation of the results and to all stages of the paper writing	contributed to the conception and design of the study, to the interpretation of the results and to all stages of the paper writing	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology	YES
5476749	28676803	LB	2	assisted with the statistical analysis and description	assisted with the statistical analysis and description	Analyzed the data	Formal analysis	YES
5476749	28676803	MA	2	research on this topic|was responsible for the data collection and contributed to the data analysis and interpretation	research on this topic	-	-	NO
5476749	28676803	MA	2	research on this topic|was responsible for the data collection and contributed to the data analysis and interpretation	was responsible for the data collection and contributed to the data analysis and interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5476749	28676803	YC	2	contributed to the conception and design of the study, to data acquisition and data analysis, to the interpretation of the results and to all stages of the paper writing	contributed to the conception and design of the study, to data acquisition and data analysis, to the interpretation of the results and to all stages of the paper writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Resources	YES
4443700	26064908	Chao-Long Chen	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4443700	26064908	Chih-Jen Chen	PLoS52	analyzed the data|contributed reagents/materials/analysis tools|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
4443700	26064908	Chih-Jen Chen	PLoS52	analyzed the data|contributed reagents/materials/analysis tools|wrote the paper	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4443700	26064908	Chih-Jen Chen	PLoS52	analyzed the data|contributed reagents/materials/analysis tools|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4443700	26064908	Jiin-Haur Chuang	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
4443700	26064908	Kuo-Shu Tang	PLoS52	performed the experiments|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
4443700	26064908	Kuo-Shu Tang	PLoS52	performed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4443700	26064908	Li-Tung Huang	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4443700	26064908	Mao-Meng Tiao	PLoS52	conceived and designed the experiments|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4443700	26064908	Mao-Meng Tiao	PLoS52	conceived and designed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4443700	26064908	Ying-Hsien Huang	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
2358885	18394155	JSH	2	was responsible for obtaining the data, training the research assistants, and revising the manuscript	was responsible for obtaining the data, training the research assistants, and revising the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
2358885	18394155	LDA	2	was responsible for the data analyses, revising and approving the final draft of the manuscript	was responsible for the data analyses, revising and approving the final draft of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
2358885	18394155	RGM	2	was responsible for the initial training of the research assistants to insure quality control, the design of the study, and was primary author of the manuscript	was responsible for the initial training of the research assistants to insure quality control, the design of the study, and was primary author of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Methodology|Validation|Writing - Original Draft	YES
2358885	18394155	SIB	2	designed the data management system, the analytical approach to the data and revising the manuscript	designed the data management system, the analytical approach to the data and revising the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Data curation|Formal analysis|Writing - Review & Editing	YES
5106812	27835941	All authors	PLoS52	have read, edited and approved the current version of the manuscript	have read, edited and approved the current version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5106812	27835941	CL	PLoS52	designed the experiments|wrote the paper	designed the experiments	Conceived and designed the experiments	Methodology	YES
5106812	27835941	CL	PLoS52	designed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5106812	27835941	CT	PLoS52	performed bioinformatic analysis of whole-genome shotgun sequence data	performed bioinformatic analysis of whole-genome shotgun sequence data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5106812	27835941	DM	PLoS52	developed dash/vb9104 population and hindmarsh/w1 population, respectively	developed dash/vb9104 population and hindmarsh/w1 population, respectively	-	-	NO
5106812	27835941	HL	PLoS52	mapped the markers in hindmarsh/w1	mapped the markers in hindmarsh/w1	-	-	NO
5106812	27835941	JW	PLoS52	genotyped markers of dash/vb9104 population	genotyped markers of dash/vb9104 population	Performed the experiments	Investigation	YES
5106812	27835941	JY	PLoS52	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5106812	27835941	JZ	PLoS52	contributed to phenotype dash/vb9104 population	contributed to phenotype dash/vb9104 population	Performed the experiments	Investigation	YES
5106812	27835941	QJ	PLoS52	designed the experiments|genotyped markers of dash/vb9104 population|wrote the paper	designed the experiments	Conceived and designed the experiments	Methodology	YES
5106812	27835941	QJ	PLoS52	designed the experiments|genotyped markers of dash/vb9104 population|wrote the paper	genotyped markers of dash/vb9104 population	Performed the experiments	Investigation	YES
5106812	27835941	QJ	PLoS52	designed the experiments|genotyped markers of dash/vb9104 population|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5106812	27835941	SB	PLoS52	developed dash/vb9104 population and hindmarsh/w1 population, respectively	developed dash/vb9104 population and hindmarsh/w1 population, respectively	-	-	NO
5106812	27835941	SW	PLoS52	mapped the markers in hindmarsh/w1	mapped the markers in hindmarsh/w1	-	-	NO
5106812	27835941	XZ	PLoS52	carried out whole-genome shotgun sequence data analysis and hindmarsh/w1 phenotyping	carried out whole-genome shotgun sequence data analysis and hindmarsh/w1 phenotyping	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
2847537	20236544	AMS	1	Provision of study materials or patients|Critical revision of the article for important intellectual content|Final approval of the article|Collection and assembly of data	Provision of study materials or patients	-	-	NO
2847537	20236544	AMS	1	Provision of study materials or patients|Critical revision of the article for important intellectual content|Final approval of the article|Collection and assembly of data	Critical revision of the article for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
2847537	20236544	AMS	1	Provision of study materials or patients|Critical revision of the article for important intellectual content|Final approval of the article|Collection and assembly of data	Final approval of the article	-	-	NO
2847537	20236544	AMS	1	Provision of study materials or patients|Critical revision of the article for important intellectual content|Final approval of the article|Collection and assembly of data	Collection and assembly of data	Performed the experiments	Investigation	YES
2847537	20236544	AR	1	Provision of study materials or patients|Critical revision of the article for important intellectual content|Final approval of the article|Collection and assembly of data	Provision of study materials or patients	-	-	NO
2847537	20236544	AR	1	Provision of study materials or patients|Critical revision of the article for important intellectual content|Final approval of the article|Collection and assembly of data	Critical revision of the article for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
2847537	20236544	AR	1	Provision of study materials or patients|Critical revision of the article for important intellectual content|Final approval of the article|Collection and assembly of data	Final approval of the article	-	-	NO
2847537	20236544	AR	1	Provision of study materials or patients|Critical revision of the article for important intellectual content|Final approval of the article|Collection and assembly of data	Collection and assembly of data	Performed the experiments	Investigation	YES
2847537	20236544	AT	1	Provision of study materials or patients|Critical revision of the article for important intellectual content|Final approval of the article|Collection and assembly of data	Provision of study materials or patients	-	-	NO
2847537	20236544	AT	1	Provision of study materials or patients|Critical revision of the article for important intellectual content|Final approval of the article|Collection and assembly of data	Critical revision of the article for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
2847537	20236544	AT	1	Provision of study materials or patients|Critical revision of the article for important intellectual content|Final approval of the article|Collection and assembly of data	Final approval of the article	-	-	NO
2847537	20236544	AT	1	Provision of study materials or patients|Critical revision of the article for important intellectual content|Final approval of the article|Collection and assembly of data	Collection and assembly of data	Performed the experiments	Investigation	YES
2847537	20236544	AV	1	Provision of study materials or patients|Critical revision of the article for important intellectual content|Final approval of the article|Collection and assembly of data	Provision of study materials or patients	-	-	NO
2847537	20236544	AV	1	Provision of study materials or patients|Critical revision of the article for important intellectual content|Final approval of the article|Collection and assembly of data	Critical revision of the article for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
2847537	20236544	AV	1	Provision of study materials or patients|Critical revision of the article for important intellectual content|Final approval of the article|Collection and assembly of data	Final approval of the article	-	-	NO
2847537	20236544	AV	1	Provision of study materials or patients|Critical revision of the article for important intellectual content|Final approval of the article|Collection and assembly of data	Collection and assembly of data	Performed the experiments	Investigation	YES
2847537	20236544	DM	1	Provision of study materials or patients|Critical revision of the article for important intellectual content|Final approval of the article|Collection and assembly of data	Provision of study materials or patients	-	-	NO
2847537	20236544	DM	1	Provision of study materials or patients|Critical revision of the article for important intellectual content|Final approval of the article|Collection and assembly of data	Critical revision of the article for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
2847537	20236544	DM	1	Provision of study materials or patients|Critical revision of the article for important intellectual content|Final approval of the article|Collection and assembly of data	Final approval of the article	-	-	NO
2847537	20236544	DM	1	Provision of study materials or patients|Critical revision of the article for important intellectual content|Final approval of the article|Collection and assembly of data	Collection and assembly of data	Performed the experiments	Investigation	YES
2847537	20236544	FL	1	Provision of study materials or patients|Final approval of the article|Collection and assembly of data	Provision of study materials or patients	-	-	NO
2847537	20236544	FL	1	Provision of study materials or patients|Final approval of the article|Collection and assembly of data	Final approval of the article	-	-	NO
2847537	20236544	FL	1	Provision of study materials or patients|Final approval of the article|Collection and assembly of data	Collection and assembly of data	Performed the experiments	Investigation	YES
2847537	20236544	FLo	1	Critical revision of the article for important intellectual content	Critical revision of the article for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
2847537	20236544	JP	1	Provision of study materials or patients|Critical revision of the article for important intellectual content|Final approval of the article|Collection and assembly of data	Provision of study materials or patients	-	-	NO
2847537	20236544	JP	1	Provision of study materials or patients|Critical revision of the article for important intellectual content|Final approval of the article|Collection and assembly of data	Critical revision of the article for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
2847537	20236544	JP	1	Provision of study materials or patients|Critical revision of the article for important intellectual content|Final approval of the article|Collection and assembly of data	Final approval of the article	-	-	NO
2847537	20236544	JP	1	Provision of study materials or patients|Critical revision of the article for important intellectual content|Final approval of the article|Collection and assembly of data	Collection and assembly of data	Performed the experiments	Investigation	YES
2847537	20236544	JR	1	Provision of study materials or patients|Critical revision of the article for important intellectual content|Final approval of the article|Collection and assembly of data	Provision of study materials or patients	-	-	NO
2847537	20236544	JR	1	Provision of study materials or patients|Critical revision of the article for important intellectual content|Final approval of the article|Collection and assembly of data	Critical revision of the article for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
2847537	20236544	JR	1	Provision of study materials or patients|Critical revision of the article for important intellectual content|Final approval of the article|Collection and assembly of data	Final approval of the article	-	-	NO
2847537	20236544	JR	1	Provision of study materials or patients|Critical revision of the article for important intellectual content|Final approval of the article|Collection and assembly of data	Collection and assembly of data	Performed the experiments	Investigation	YES
2847537	20236544	LFLC	1	Conception, design, analysis, interpretation of the data, drafting of the article and obtaining of funding|Provision of study materials or patients|Final approval of the article|Collection and assembly of data	Conception, design, analysis, interpretation of the data, drafting of the article and obtaining of funding	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Funding acquisition|Writing - Original Draft	YES
2847537	20236544	LFLC	1	Conception, design, analysis, interpretation of the data, drafting of the article and obtaining of funding|Provision of study materials or patients|Final approval of the article|Collection and assembly of data	Provision of study materials or patients	-	-	NO
2847537	20236544	LFLC	1	Conception, design, analysis, interpretation of the data, drafting of the article and obtaining of funding|Provision of study materials or patients|Final approval of the article|Collection and assembly of data	Final approval of the article	-	-	NO
2847537	20236544	LFLC	1	Conception, design, analysis, interpretation of the data, drafting of the article and obtaining of funding|Provision of study materials or patients|Final approval of the article|Collection and assembly of data	Collection and assembly of data	Performed the experiments	Investigation	YES
2847537	20236544	LG	1	Provision of study materials or patients|Critical revision of the article for important intellectual content|Final approval of the article|Collection and assembly of data	Provision of study materials or patients	-	-	NO
2847537	20236544	LG	1	Provision of study materials or patients|Critical revision of the article for important intellectual content|Final approval of the article|Collection and assembly of data	Critical revision of the article for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
2847537	20236544	LG	1	Provision of study materials or patients|Critical revision of the article for important intellectual content|Final approval of the article|Collection and assembly of data	Final approval of the article	-	-	NO
2847537	20236544	LG	1	Provision of study materials or patients|Critical revision of the article for important intellectual content|Final approval of the article|Collection and assembly of data	Collection and assembly of data	Performed the experiments	Investigation	YES
2847537	20236544	PV	1	Provision of study materials or patients|Critical revision of the article for important intellectual content|Final approval of the article|Collection and assembly of data	Provision of study materials or patients	-	-	NO
2847537	20236544	PV	1	Provision of study materials or patients|Critical revision of the article for important intellectual content|Final approval of the article|Collection and assembly of data	Critical revision of the article for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
2847537	20236544	PV	1	Provision of study materials or patients|Critical revision of the article for important intellectual content|Final approval of the article|Collection and assembly of data	Final approval of the article	-	-	NO
2847537	20236544	PV	1	Provision of study materials or patients|Critical revision of the article for important intellectual content|Final approval of the article|Collection and assembly of data	Collection and assembly of data	Performed the experiments	Investigation	YES
2847537	20236544	RRV	1	Determination of saquinavir plasma concentrations|Critical revision of the article for important intellectual content|Final approval of the article	Determination of saquinavir plasma concentrations	Performed the experiments	Investigation	YES
2847537	20236544	RRV	1	Determination of saquinavir plasma concentrations|Critical revision of the article for important intellectual content|Final approval of the article	Critical revision of the article for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
2847537	20236544	RRV	1	Determination of saquinavir plasma concentrations|Critical revision of the article for important intellectual content|Final approval of the article	Final approval of the article	-	-	NO
3373141	22701353	P. Liu	2	contributed equally to this work	contributed equally to this work	-	-	NO
3373141	22701353	S. Wang	2	contributed equally to this work	contributed equally to this work	-	-	NO
4401559	25884853	GY	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401559	25884853	GY	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401559	25884853	SC	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401559	25884853	SC	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401559	25884853	WS	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401559	25884853	XX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401559	25884853	XX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401559	25884853	XX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401559	25884853	XX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401559	25884853	XX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401559	25884853	YT	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401559	25884853	YT	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5476771	28676817	AM	2	provided the value comments and revised the grammar of the manuscript	provided the value comments and revised the grammar of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5476771	28676817	AZ	2	designed the study and provide guidance on the whole study	designed the study and provide guidance on the whole study	Conceived and designed the experiments	Methodology|Supervision	YES
5476771	28676817	DL	2	prepared plant materials|provided the value comments and revised the grammar of the manuscript	prepared plant materials	Performed the experiments	Investigation	YES
5476771	28676817	DL	2	prepared plant materials|provided the value comments and revised the grammar of the manuscript	provided the value comments and revised the grammar of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5476771	28676817	JL	2	carried out the plant materials culture, qrt pcr analysis, data analysis, and drafted the manuscript	carried out the plant materials culture, qrt pcr analysis, data analysis, and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5476771	28676817	JS	2	prepared plant materials	prepared plant materials	Performed the experiments	Investigation	YES
5476771	28676817	KZ	2	prepared plant materials	prepared plant materials	Performed the experiments	Investigation	YES
5476771	28676817	LH	2	prepared plant materials	prepared plant materials	Performed the experiments	Investigation	YES
5476771	28676817	MP	2	carried out the plant materials culture, qrt pcr analysis, data analysis, and drafted the manuscript	carried out the plant materials culture, qrt pcr analysis, data analysis, and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5476771	28676817	WY	2	designed the study and provide guidance on the whole study	designed the study and provide guidance on the whole study	Conceived and designed the experiments	Methodology|Supervision	YES
5476771	28676817	XL	2	carried out the plant materials culture, qrt pcr analysis, data analysis, and drafted the manuscript	carried out the plant materials culture, qrt pcr analysis, data analysis, and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4186668	25249443	All authors	2	have given approval to the final version of the manuscript	have given approval to the final version of the manuscript	-	-	NO
4165719	25227265	All authors	2	critically reviewed and revised the manuscript|contributed to the intellectual content of the manuscript and approved the final version of the manuscript	critically reviewed and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4165719	25227265	All authors	2	critically reviewed and revised the manuscript|contributed to the intellectual content of the manuscript and approved the final version of the manuscript	contributed to the intellectual content of the manuscript and approved the final version of the manuscript	-	-	NO
4165719	25227265	CM	2	provided input into the design and implementation of the study	provided input into the design and implementation of the study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4165719	25227265	DE	2	conceived and designed the study|undertook the data analysis and wrote the first draft of the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4165719	25227265	DE	2	conceived and designed the study|undertook the data analysis and wrote the first draft of the manuscript	undertook the data analysis and wrote the first draft of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4165719	25227265	IS	2	provided input into the design and implementation of the study	provided input into the design and implementation of the study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4165719	25227265	LM	2	was involved in the implementation of the study, supervised data collection and performed data management	was involved in the implementation of the study, supervised data collection and performed data management	Performed the experiments|Analyzed the data	Data curation|Investigation|Supervision	YES
4165719	25227265	MF	2	oversaw statistical analysis and interpretation of data	oversaw statistical analysis and interpretation of data	Analyzed the data	Formal analysis|Supervision	YES
4165719	25227265	MM	2	conceived and designed the study|oversaw statistical analysis and interpretation of data	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4165719	25227265	MM	2	conceived and designed the study|oversaw statistical analysis and interpretation of data	oversaw statistical analysis and interpretation of data	Analyzed the data	Formal analysis|Supervision	YES
4165719	25227265	PM	2	provided input into the design and implementation of the study	provided input into the design and implementation of the study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
2365941	18426582	AS	2	participated in data collection and analysis	participated in data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
2365941	18426582	AW	2	participated in data collection and analysis	participated in data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
2365941	18426582	CL	2	participated in data collection and analysis	participated in data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
2365941	18426582	ER	2	participated in data collection and analysis	participated in data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
2365941	18426582	JC	2	participated in the study design and helped draft the manuscript while aiding in data collection	participated in the study design and helped draft the manuscript while aiding in data collection	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
2365941	18426582	JM	2	participated in the study design and helped draft the manuscript while aiding in data collection	participated in the study design and helped draft the manuscript while aiding in data collection	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
2365941	18426582	JS	2	participated in the study design and helped draft the manuscript while aiding in data collection	participated in the study design and helped draft the manuscript while aiding in data collection	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
2365941	18426582	MR	2	participated in data collection and analysis	participated in data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
2365941	18426582	ST	2	participated in the study design and helped draft the manuscript while aiding in data collection	participated in the study design and helped draft the manuscript while aiding in data collection	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
2365941	18426582	TB	2	participated in the study design and helped draft the manuscript while aiding in data collection	participated in the study design and helped draft the manuscript while aiding in data collection	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
2365941	18426582	VD	2	participated in data collection and analysis	participated in data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
2365941	18426582	all authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
2852372	20334651	EA	2	share first authorship of the current manuscript|performed drug treatment studies, western blot analysis, cell cycle analysis, kinase assays and virus infections	share first authorship of the current manuscript	-	-	NO
2852372	20334651	EA	2	share first authorship of the current manuscript|performed drug treatment studies, western blot analysis, cell cycle analysis, kinase assays and virus infections	performed drug treatment studies, western blot analysis, cell cycle analysis, kinase assays and virus infections	Performed the experiments	Investigation	YES
2852372	20334651	FK	2	coordinated the research, experimental design and drafting of the manuscript	coordinated the research, experimental design and drafting of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft	YES
2852372	20334651	IG	2	share first authorship of the current manuscript|performed western blot analysis, transfections, mtt assays and luciferase assays	share first authorship of the current manuscript	-	-	NO
2852372	20334651	IG	2	share first authorship of the current manuscript|performed western blot analysis, transfections, mtt assays and luciferase assays	performed western blot analysis, transfections, mtt assays and luciferase assays	Performed the experiments	Investigation	YES
2852372	20334651	KK	2	aided in the preparation of the manuscript and in the experimental design	aided in the preparation of the manuscript and in the experimental design	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5106845	27835938	CP	2	performed the data collection	performed the data collection	Performed the experiments	Investigation	YES
5106845	27835938	HW	2	analyzed the sequence data|analyzed the phenotypic data	analyzed the sequence data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5106845	27835938	HW	2	analyzed the sequence data|analyzed the phenotypic data	analyzed the phenotypic data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5106845	27835938	JS	2	analyzed the phenotypic data	analyzed the phenotypic data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5106845	27835938	JY	2	performed the data collection|performed the ssr experiment	performed the data collection	Performed the experiments	Investigation	YES
5106845	27835938	JY	2	performed the data collection|performed the ssr experiment	performed the ssr experiment	Performed the experiments	Investigation	YES
5106845	27835938	MS	2	designed the experiment	designed the experiment	Conceived and designed the experiments	Methodology	YES
5106845	27835938	NW	2	performed the ssr experiment	performed the ssr experiment	Performed the experiments	Investigation	YES
5106845	27835938	QM	2	analyzed the sequence data	analyzed the sequence data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5106845	27835938	SC	2	conducted the qtl analysis and qrt-pcr analysis	conducted the qtl analysis and qrt-pcr analysis	Performed the experiments	Investigation	YES
5106845	27835938	SF	2	designed the experiment	designed the experiment	Conceived and designed the experiments	Methodology	YES
5106845	27835938	SY	2	designed the experiment	designed the experiment	Conceived and designed the experiments	Methodology	YES
5106845	27835938	XJ	2	performed the data collection|analyzed the phenotypic data|performed the ssr experiment|wrote and revised the manuscript	performed the data collection	Performed the experiments	Investigation	YES
5106845	27835938	XJ	2	performed the data collection|analyzed the phenotypic data|performed the ssr experiment|wrote and revised the manuscript	analyzed the phenotypic data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5106845	27835938	XJ	2	performed the data collection|analyzed the phenotypic data|performed the ssr experiment|wrote and revised the manuscript	performed the ssr experiment	Performed the experiments	Investigation	YES
5106845	27835938	XJ	2	performed the data collection|analyzed the phenotypic data|performed the ssr experiment|wrote and revised the manuscript	wrote and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
2853483	20298614	AM	2	made substantial contributions to interpretation of data, and was involved in revising the draft critically for important intellectual content	made substantial contributions to interpretation of data, and was involved in revising the draft critically for important intellectual content	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
2853483	20298614	FS	2	made substantial contributions to acquisition of data, and was involved in revising the draft critically for important intellectual content	made substantial contributions to acquisition of data, and was involved in revising the draft critically for important intellectual content	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Resources|Writing - Original Draft	YES
2853483	20298614	LT	2	made substantial contributions to analyze data, and was involved in revising the draft critically for important intellectual content	made substantial contributions to analyze data, and was involved in revising the draft critically for important intellectual content	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
2853483	20298614	MS	2	conceived of the study, participated in its design, made substantial contributions to acquisition of data, and helped to draft the manuscript	conceived of the study, participated in its design, made substantial contributions to acquisition of data, and helped to draft the manuscript	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Investigation|Methodology|Resources|Writing - Original Draft	YES
2853483	20298614	QC	2	wrote study protocol, designed the questionnaire, carried out medical chart review, performed the statistical analysis and drafted the manuscript	wrote study protocol, designed the questionnaire, carried out medical chart review, performed the statistical analysis and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
2853483	20298614	SC	2	performed the spirometry test, carried out the questionnaire survey and coordinated the study	performed the spirometry test, carried out the questionnaire survey and coordinated the study	Performed the experiments	Investigation|Project administration	YES
4401561	25884831	DZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401561	25884831	JD	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401561	25884831	JL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401561	25884831	JW	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401561	25884831	KW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401561	25884831	LZ	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401561	25884831	PG	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401561	25884831	QA	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401561	25884831	QA	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401561	25884831	QC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401561	25884831	RJ	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4401561	25884831	RJ	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401561	25884831	YJ	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401561	25884831	YJ	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
2397397	18442381	CL	2	collected all data except the accelerometer data and were involved in the drafting of the manuscript	collected all data except the accelerometer data and were involved in the drafting of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
2397397	18442381	GA	2	were involved in the statistical analysis, the interpretation of data and the writing of the manuscript	were involved in the statistical analysis, the interpretation of data and the writing of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
2397397	18442381	HA	2	were involved in the statistical analysis, the interpretation of data and the writing of the manuscript	were involved in the statistical analysis, the interpretation of data and the writing of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
2397397	18442381	JB	2	collected all data except the accelerometer data and were involved in the drafting of the manuscript	collected all data except the accelerometer data and were involved in the drafting of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
2397397	18442381	MD	2	collected and analyzed the accelerometer data	collected and analyzed the accelerometer data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
2397397	18442381	MK	2	designed the study, worked with the analysis and the interpretation of data and was in charge of writing the manuscript	designed the study, worked with the analysis and the interpretation of data and was in charge of writing the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
2397397	18442381	PG	2	designed the study and was involved in collecting the data	designed the study and was involved in collecting the data	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
2397397	18442381	SSL	2	collected all data except the accelerometer data and were involved in the drafting of the manuscript	collected all data except the accelerometer data and were involved in the drafting of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5476776	28676812	FK	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5476776	28676812	HS	PLoS52	developed the new methods	developed the new methods	Performed the experiments	Methodology	YES
5476776	28676812	JY	PLoS52	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5476776	28676812	QL	PLoS52	designed the study|performed the experiments|analyzed the data|wrote the paper	designed the study	Conceived and designed the experiments	Methodology	YES
5476776	28676812	QL	PLoS52	designed the study|performed the experiments|analyzed the data|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5476776	28676812	QL	PLoS52	designed the study|performed the experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5476776	28676812	QL	PLoS52	designed the study|performed the experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5476776	28676812	RJ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5476776	28676812	WC	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5476776	28676812	YK	PLoS52	developed the new methods	developed the new methods	Performed the experiments	Methodology	YES
5476776	28676812	YW	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
4169647	25239379	AM	2	made substantial contributions to the acquisition, analysis and interpretation of data, revised the paper for important intellectual content and gave final approval for submission of the manuscript	made substantial contributions to the acquisition, analysis and interpretation of data, revised the paper for important intellectual content and gave final approval for submission of the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Review & Editing	YES
4169647	25239379	DS	2	made substantial contributions to the conception and design of the study	made substantial contributions to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4169647	25239379	FWM	2	made substantial contributions to the conception and design of the study	made substantial contributions to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4169647	25239379	JKBM	2	conceived and designed the study, supervised data collection, led the analysis of data, wrote the first draft of the paper and revised the paper for substantial intellectual content|was responsible for the final submission of the paper	conceived and designed the study, supervised data collection, led the analysis of data, wrote the first draft of the paper and revised the paper for substantial intellectual content	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
4169647	25239379	JKBM	2	conceived and designed the study, supervised data collection, led the analysis of data, wrote the first draft of the paper and revised the paper for substantial intellectual content|was responsible for the final submission of the paper	was responsible for the final submission of the paper	-	-	NO
4169647	25239379	JT	2	made substantial contributions to the conception and design of the study	made substantial contributions to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4169647	25239379	RKW	2	made substantial contributions to the conception and design of the study	made substantial contributions to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4169647	25239379	RN	2	made substantial contributions to the acquisition, analysis and interpretation of data, revised the paper for important intellectual content and gave final approval for submission of the manuscript	made substantial contributions to the acquisition, analysis and interpretation of data, revised the paper for important intellectual content and gave final approval for submission of the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Review & Editing	YES
4169647	25239379	RS	2	made substantial contributions to the acquisition, analysis and interpretation of data, revised the paper for important intellectual content and gave final approval for submission of the manuscript	made substantial contributions to the acquisition, analysis and interpretation of data, revised the paper for important intellectual content and gave final approval for submission of the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Review & Editing	YES
5109649	27842490	AK	2	designed the project conceptually, developed experimental strategies and interpreted data|performed the molecular biology experiments and conducted next generation sequencing|wrote the manuscript|performed experiments, bioinformatics and statistical analysis	designed the project conceptually, developed experimental strategies and interpreted data	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
5109649	27842490	AK	2	designed the project conceptually, developed experimental strategies and interpreted data|performed the molecular biology experiments and conducted next generation sequencing|wrote the manuscript|performed experiments, bioinformatics and statistical analysis	performed the molecular biology experiments and conducted next generation sequencing	Performed the experiments	Investigation	YES
5109649	27842490	AK	2	designed the project conceptually, developed experimental strategies and interpreted data|performed the molecular biology experiments and conducted next generation sequencing|wrote the manuscript|performed experiments, bioinformatics and statistical analysis	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5109649	27842490	AK	2	designed the project conceptually, developed experimental strategies and interpreted data|performed the molecular biology experiments and conducted next generation sequencing|wrote the manuscript|performed experiments, bioinformatics and statistical analysis	performed experiments, bioinformatics and statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5109649	27842490	CB	2	performed the molecular biology experiments and conducted next generation sequencing	performed the molecular biology experiments and conducted next generation sequencing	Performed the experiments	Investigation	YES
5109649	27842490	CF	2	performed experiments, bioinformatics and statistical analysis	performed experiments, bioinformatics and statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5109649	27842490	JH	2	performed experiments, bioinformatics and statistical analysis	performed experiments, bioinformatics and statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5109649	27842490	KW	2	performed experiments, bioinformatics and statistical analysis	performed experiments, bioinformatics and statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5109649	27842490	LH	2	performed the molecular biology experiments and conducted next generation sequencing|supported construct generation	performed the molecular biology experiments and conducted next generation sequencing	Performed the experiments	Investigation	YES
5109649	27842490	LH	2	performed the molecular biology experiments and conducted next generation sequencing|supported construct generation	supported construct generation	Performed the experiments	Investigation	YES
5109649	27842490	MG	2	oversaw the project and gave advice on study design	oversaw the project and gave advice on study design	Conceived and designed the experiments	Methodology|Supervision	YES
5109649	27842490	MW	2	performed the molecular biology experiments and conducted next generation sequencing|supported construct generation	performed the molecular biology experiments and conducted next generation sequencing	Performed the experiments	Investigation	YES
5109649	27842490	MW	2	performed the molecular biology experiments and conducted next generation sequencing|supported construct generation	supported construct generation	Performed the experiments	Investigation	YES
5109649	27842490	SB	2	designed the project conceptually, developed experimental strategies and interpreted data|wrote the manuscript|oversaw the project and gave advice on study design	designed the project conceptually, developed experimental strategies and interpreted data	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
5109649	27842490	SB	2	designed the project conceptually, developed experimental strategies and interpreted data|wrote the manuscript|oversaw the project and gave advice on study design	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5109649	27842490	SB	2	designed the project conceptually, developed experimental strategies and interpreted data|wrote the manuscript|oversaw the project and gave advice on study design	oversaw the project and gave advice on study design	Conceived and designed the experiments	Methodology|Supervision	YES
5109649	27842490	SHS	2	designed the project conceptually, developed experimental strategies and interpreted data|performed the molecular biology experiments and conducted next generation sequencing|wrote the manuscript|oversaw the project and gave advice on study design	designed the project conceptually, developed experimental strategies and interpreted data	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
5109649	27842490	SHS	2	designed the project conceptually, developed experimental strategies and interpreted data|performed the molecular biology experiments and conducted next generation sequencing|wrote the manuscript|oversaw the project and gave advice on study design	performed the molecular biology experiments and conducted next generation sequencing	Performed the experiments	Investigation	YES
5109649	27842490	SHS	2	designed the project conceptually, developed experimental strategies and interpreted data|performed the molecular biology experiments and conducted next generation sequencing|wrote the manuscript|oversaw the project and gave advice on study design	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5109649	27842490	SHS	2	designed the project conceptually, developed experimental strategies and interpreted data|performed the molecular biology experiments and conducted next generation sequencing|wrote the manuscript|oversaw the project and gave advice on study design	oversaw the project and gave advice on study design	Conceived and designed the experiments	Methodology|Supervision	YES
5109649	27842490	VB	2	performed experiments, bioinformatics and statistical analysis	performed experiments, bioinformatics and statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
2859392	20338069	EEN	2	took part in genotyping	took part in genotyping	Performed the experiments	Investigation	YES
2859392	20338069	NW	2	participated in the study design|took part in genotyping	participated in the study design	Conceived and designed the experiments	Methodology	YES
2859392	20338069	NW	2	participated in the study design|took part in genotyping	took part in genotyping	Performed the experiments	Investigation	YES
2859392	20338069	SK	2	participated in the study design|revised and finalised the manuscript	participated in the study design	Conceived and designed the experiments	Methodology	YES
2859392	20338069	SK	2	participated in the study design|revised and finalised the manuscript	revised and finalised the manuscript	Wrote the paper	Writing - Review & Editing	YES
2859392	20338069	SL	2	participated in the study design|coordinated the study	participated in the study design	Conceived and designed the experiments	Methodology	YES
2859392	20338069	SL	2	participated in the study design|coordinated the study	coordinated the study	-	Project administration	YES
2859392	20338069	SU	2	participated in the study design|performed genotyping, cd4 counts and hiv-1 viral load determination, analysed the data and drafted the manuscript	participated in the study design	Conceived and designed the experiments	Methodology	YES
2859392	20338069	SU	2	participated in the study design|performed genotyping, cd4 counts and hiv-1 viral load determination, analysed the data and drafted the manuscript	performed genotyping, cd4 counts and hiv-1 viral load determination, analysed the data and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
2859392	20338069	TK	2	participated in the study design	participated in the study design	Conceived and designed the experiments	Methodology	YES
2859392	20338069	TS	2	revised and finalised the manuscript	revised and finalised the manuscript	Wrote the paper	Writing - Review & Editing	YES
2859392	20338069	WM	2	participated in the study design|coordinated the study	participated in the study design	Conceived and designed the experiments	Methodology	YES
2859392	20338069	WM	2	participated in the study design|coordinated the study	coordinated the study	-	Project administration	YES
4401562	25884835	BX	PLoS5	Analyzed the data|Edited the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4401562	25884835	BX	PLoS5	Analyzed the data|Edited the manuscript	Edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
4401562	25884835	LW	PLoS5	Analyzed the data|Edited the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4401562	25884835	LW	PLoS5	Analyzed the data|Edited the manuscript	Edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
4401562	25884835	LZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Edited the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401562	25884835	LZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Edited the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4401562	25884835	LZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Edited the manuscript	Edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
4401562	25884835	NW	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Edited the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4401562	25884835	NW	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Edited the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4401562	25884835	NW	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Edited the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401562	25884835	NW	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Edited the manuscript	Edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
4401562	25884835	ST	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Edited the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4401562	25884835	ST	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Edited the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401562	25884835	ST	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Edited the manuscript	Edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
4401562	25884835	XM	PLoS5	Interpreted the data|Edited the manuscript	Interpreted the data	Analyzed the data	Formal analysis	YES
4401562	25884835	XM	PLoS5	Interpreted the data|Edited the manuscript	Edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
4401562	25884835	YL	PLoS5	Conceived and designed the experiments|Edited the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401562	25884835	YL	PLoS5	Conceived and designed the experiments|Edited the manuscript	Edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
4401562	25884835	YX	PLoS5	Performed the experiments|Edited the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4401562	25884835	YX	PLoS5	Performed the experiments|Edited the manuscript	Edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
4401562	25884835	YZ	PLoS5	Interpreted the data|Edited the manuscript	Interpreted the data	Analyzed the data	Formal analysis	YES
4401562	25884835	YZ	PLoS5	Interpreted the data|Edited the manuscript	Edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
4401562	25884835	ZS	PLoS5	Conceived and designed the experiments|Edited the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401562	25884835	ZS	PLoS5	Conceived and designed the experiments|Edited the manuscript	Edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5476780	28676814	JL	2	designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
5476780	28676814	JY	2	performed the research	performed the research	Performed the experiments	Investigation	YES
5476780	28676814	WT	2	performed the research	performed the research	Performed the experiments	Investigation	YES
5476780	28676814	YC	2	designed the research|performed the research|drafted the article	designed the research	Conceived and designed the experiments	Methodology	YES
5476780	28676814	YC	2	designed the research|performed the research|drafted the article	performed the research	Performed the experiments	Investigation	YES
5476780	28676814	YC	2	designed the research|performed the research|drafted the article	drafted the article	Wrote the paper	Writing - Original Draft	YES
5476780	28676814	YLZ	2	designed the research|drafted the article	designed the research	Conceived and designed the experiments	Methodology	YES
5476780	28676814	YLZ	2	designed the research|drafted the article	drafted the article	Wrote the paper	Writing - Original Draft	YES
5476780	28676814	YYZ	2	performed the research	performed the research	Performed the experiments	Investigation	YES
5476780	28676814	ZX	2	performed the research	performed the research	Performed the experiments	Investigation	YES
2869332	20416063	HIV	2	prevalence and incidence	prevalence and incidence	-	-	NO
2869332	20416063	HPRU	2	oversaw implementation of all trials and studies mentioned, as well as drafting of the manuscript	oversaw implementation of all trials and studies mentioned, as well as drafting of the manuscript	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Original Draft	YES
2869332	20416063	JM	2	provided contraceptive data	provided contraceptive data	Contributed reagents/materials/analysis tools	Resources	YES
2869332	20416063	NM	2	provided information on community entry and interaction	provided information on community entry and interaction	-	-	NO
2869332	20416063	VG	2	provided the content of the sections on counselling in the south african context	provided the content of the sections on counselling in the south african context	Wrote the paper	Writing - Original Draft	YES
2443365	18582383	AYM	2	was responsible for significant reviewing and assistance with the writing and final formatting of the article	was responsible for significant reviewing and assistance with the writing and final formatting of the article	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
2443365	18582383	GRW	2	conceptualized the idea of the pre-diagnostic criteria, prehabilitation exercise protocol, and was the principal author of the manuscript	conceptualized the idea of the pre-diagnostic criteria, prehabilitation exercise protocol, and was the principal author of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Writing - Original Draft	YES
4172689	25249214	CS	2	performed the lab work	performed the lab work	Performed the experiments	Investigation	YES
4172689	25249214	LJ	2	data analysis	data analysis	Analyzed the data	Formal analysis	YES
4172689	25249214	MC	2	performed phylogenetic analysis	performed phylogenetic analysis	Performed the experiments	Investigation	YES
4172689	25249214	MS	2	data analysis and manuscript preparation	data analysis and manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4172689	25249214	RD	2	design the study, data analysis and manuscript preparation	design the study, data analysis and manuscript preparation	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4172689	25249214	SK	2	lab work and data analysis	lab work and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3614852	23675253	all authors	4	The paper was designed and implemented by	The paper was designed and implemented by	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5109656	27842516	DAC	2	conceived the study|wrote the original manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5109656	27842516	DAC	2	conceived the study|wrote the original manuscript	wrote the original manuscript	Wrote the paper	Writing - Original Draft	YES
5109656	27842516	PDM	2	conceived the study|performed experiments and analyses|wrote the original manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5109656	27842516	PDM	2	conceived the study|performed experiments and analyses|wrote the original manuscript	performed experiments and analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5109656	27842516	PDM	2	conceived the study|performed experiments and analyses|wrote the original manuscript	wrote the original manuscript	Wrote the paper	Writing - Original Draft	YES
2873236	20398387	CAS	2	carried out the hscrp and il-6 assays	carried out the hscrp and il-6 assays	Performed the experiments	Investigation	YES
2873236	20398387	ECMG	2	participated in the design of the study	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
2873236	20398387	EJ	2	participated in the design of the study|drafted the manuscript with input from the other authors	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
2873236	20398387	EJ	2	participated in the design of the study|drafted the manuscript with input from the other authors	drafted the manuscript with input from the other authors	Wrote the paper	Writing - Original Draft	YES
2873236	20398387	JCMM	2	carried out the coagulation assays	carried out the coagulation assays	Performed the experiments	Investigation	YES
2873236	20398387	JWM	2	participated in the design of the study	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
4401563	25884713	BZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401563	25884713	BZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401563	25884713	BZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401563	25884713	JZ	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401563	25884713	JZ	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401563	25884713	QW	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401563	25884713	QW	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401563	25884713	QW	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401563	25884713	XC	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401563	25884713	ZL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401563	25884713	ZL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401563	25884713	ZL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5476784	28676810	AB	2	as an expert in irrigation of fruit trees in arid and semi-arid conditions contributed on the methodology of thermal imaging, including experimental set-up and cwsi analysis|also added to the structuring and wording of the manuscript	as an expert in irrigation of fruit trees in arid and semi-arid conditions contributed on the methodology of thermal imaging, including experimental set-up and cwsi analysis	Performed the experiments|Analyzed the data	Investigation|Methodology|Visualization	YES
5476784	28676810	AB	2	as an expert in irrigation of fruit trees in arid and semi-arid conditions contributed on the methodology of thermal imaging, including experimental set-up and cwsi analysis|also added to the structuring and wording of the manuscript	also added to the structuring and wording of the manuscript	-	-	NO
5476784	28676810	AP	2	as an expert in geospatial information systems introduced and supported the spatial descriptive statistical analysis	as an expert in geospatial information systems introduced and supported the spatial descriptive statistical analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis	YES
5476784	28676810	JK	2	carried out the experiments and all statistical data analyses|prepared the figures and tables and made a recent literature search and proposed the text	carried out the experiments and all statistical data analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5476784	28676810	JK	2	carried out the experiments and all statistical data analyses|prepared the figures and tables and made a recent literature search and proposed the text	prepared the figures and tables and made a recent literature search and proposed the text	Conceived and designed the experiments	Conceptualization|Formal analysis|Visualization	YES
5476784	28676810	MZ	2	as a horticulturist provided the objectives of the experiments, supervised the methodology, added the red line in the manuscript and supported the writing	as a horticulturist provided the objectives of the experiments, supervised the methodology, added the red line in the manuscript and supported the writing	Performed the experiments|Wrote the paper	Methodology|Supervision|Writing - Original Draft	YES
5476784	28676810	RG	2	as an expert in soil science supported the measurements of apparent soil electrical conductivity and data analysis	as an expert in soil science supported the measurements of apparent soil electrical conductivity and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5476784	28676810	WH	2	as a plant physiologist with focus on produce quality and particularly plant water status supported the analysis of tree water status	as a plant physiologist with focus on produce quality and particularly plant water status supported the analysis of tree water status	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
2503955	18616829	AK	2	participated in the sequence alignment and drafts the manuscript|participated in the design of the study	participated in the sequence alignment and drafts the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
2503955	18616829	AK	2	participated in the sequence alignment and drafts the manuscript|participated in the design of the study	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
2503955	18616829	YM	2	conceived of the study and in its design and coordination and helped to draft the manuscript	conceived of the study and in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
4176690	25261780	All authors	PLoS52	were involved in the interpretation of the data, did critical revision of the manuscript and approved its final version	were involved in the interpretation of the data, did critical revision of the manuscript and approved its final version	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4176690	25261780	CP	PLoS52	included patients	included patients	-	-	NO
4176690	25261780	DC	PLoS52	proposed the study|wrote the manuscript	proposed the study	Conceived and designed the experiments	Conceptualization	YES
4176690	25261780	DC	PLoS52	proposed the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4176690	25261780	DR	PLoS52	included patients	included patients	-	-	NO
4176690	25261780	IPM	PLoS52	included patients	included patients	-	-	NO
4176690	25261780	SM	PLoS52	included patients	included patients	-	-	NO
4176690	25261780	VP	PLoS52	analysed the data|wrote the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
4176690	25261780	VP	PLoS52	analysed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4176690	25261780	WR	PLoS52	included patients	included patients	-	-	NO
2881872	20497520	ADP	2	carried out the record linkage procedure, data quality checks, and statistical analyses	carried out the record linkage procedure, data quality checks, and statistical analyses	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
2881872	20497520	AIDS	2	participated to the record-linkage phase of the study	participated to the record-linkage phase of the study	-	-	NO
2881872	20497520	AZ	2	carried out the record linkage procedure, data quality checks, and statistical analyses	carried out the record linkage procedure, data quality checks, and statistical analyses	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
2881872	20497520	All authors	2	contributed to a critical assessment of the manuscript, and they have read and approved the final version	contributed to a critical assessment of the manuscript, and they have read and approved the final version	-	-	NO
2881872	20497520	DS	2	designed the study, interpreted the data, and prepared the manuscript|reviewed the death certificates and coded the causes of death	designed the study, interpreted the data, and prepared the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
2881872	20497520	DS	2	designed the study, interpreted the data, and prepared the manuscript|reviewed the death certificates and coded the causes of death	reviewed the death certificates and coded the causes of death	-	-	NO
2881872	20497520	GR	2	designed the study, interpreted the data, and prepared the manuscript	designed the study, interpreted the data, and prepared the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
2881872	20497520	LDM	2	carried out the record linkage procedure, data quality checks, and statistical analyses	carried out the record linkage procedure, data quality checks, and statistical analyses	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
2881872	20497520	PDP	2	designed the study, interpreted the data, and prepared the manuscript	designed the study, interpreted the data, and prepared the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
2881872	20497520	SB	2	was in charge of the italian mortality data base and participated to the record linkage phase of the study	was in charge of the italian mortality data base and participated to the record linkage phase of the study	Contributed reagents/materials/analysis tools	Software	YES
2881872	20497520	SP	2	reviewed the death certificates and coded the causes of death	reviewed the death certificates and coded the causes of death	-	-	NO
5476920	28676820	AGPs	PLoS52	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5476920	28676820	EO	PLoS52	performed the experiments|conceived and supervised the study, wrote and critically revised the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5476920	28676820	EO	PLoS52	performed the experiments|conceived and supervised the study, wrote and critically revised the manuscript	conceived and supervised the study, wrote and critically revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
5476920	28676820	JG	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5476920	28676820	NF	PLoS52	performed the experiments|conceived and supervised the study, wrote and critically revised the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5476920	28676820	NF	PLoS52	performed the experiments|conceived and supervised the study, wrote and critically revised the manuscript	conceived and supervised the study, wrote and critically revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
4401564	25884216	AJFdH	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401564	25884216	CJAP	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401564	25884216	IDN	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401564	25884216	IDN	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401564	25884216	IDN	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401564	25884216	MG	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401564	25884216	MJL	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401564	25884216	MJL	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401564	25884216	MK	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401564	25884216	SV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401564	25884216	SV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401564	25884216	SV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401564	25884216	SV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401564	25884216	SV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401564	25884216	SVV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401564	25884216	SVV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401564	25884216	SVV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401564	25884216	SVV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2890503	20500898	All authors	2	fulfill the criteria of authorship	fulfill the criteria of authorship	-	-	NO
2890503	20500898	FZ	2	carried out critical revision of the manuscript for important intellectual content	carried out critical revision of the manuscript for important intellectual content	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
2890503	20500898	KS	2	performed the literature search and was the lead author for the paper	performed the literature search and was the lead author for the paper	Performed the experiments	Formal analysis|Investigation	YES
2890503	20500898	MSC	2	carried out critical revision of the manuscript for important intellectual content	carried out critical revision of the manuscript for important intellectual content	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
2890503	20500898	RYC	2	carried out critical revision of the manuscript for important intellectual content	carried out critical revision of the manuscript for important intellectual content	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
2890503	20500898	SZ	2	contributed to reviewing the literature as well as planning and drafting the manuscript	contributed to reviewing the literature as well as planning and drafting the manuscript	Conceived and designed the experiments|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5109690	27842494	CR	2	were involved in sample and library preparation for sequencing	were involved in sample and library preparation for sequencing	Performed the experiments	Investigation	YES
5109690	27842494	DS	2	is the principal investigator and takes primary responsibility for the paper|were involved in critical revision of the manuscript	is the principal investigator and takes primary responsibility for the paper	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
5109690	27842494	DS	2	is the principal investigator and takes primary responsibility for the paper|were involved in critical revision of the manuscript	were involved in critical revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5109690	27842494	JFS	2	designed the somatic variant caller and the study|drafted the paper and interpreted the data	designed the somatic variant caller and the study	Conceived and designed the experiments	Methodology	YES
5109690	27842494	JFS	2	designed the somatic variant caller and the study|drafted the paper and interpreted the data	drafted the paper and interpreted the data	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5109690	27842494	JH	2	were involved in critical revision of the manuscript	were involved in critical revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5109690	27842494	MO	2	were involved in sample and library preparation for sequencing	were involved in sample and library preparation for sequencing	Performed the experiments	Investigation	YES
5109690	27842494	PC	2	were involved in sample and library preparation for sequencing	were involved in sample and library preparation for sequencing	Performed the experiments	Investigation	YES
5109690	27842494	PM	2	were involved in revision of the code	were involved in revision of the code	Wrote the paper	Writing - Review & Editing	YES
5109690	27842494	RV	2	were involved in revision of the code	were involved in revision of the code	Wrote the paper	Writing - Review & Editing	YES
5109690	27842494	VS	2	were involved in revision of the code	were involved in revision of the code	Wrote the paper	Writing - Review & Editing	YES
2526084	18700024	BTE	2	participated in acquisition of data and coordination of the study	participated in acquisition of data and coordination of the study	Performed the experiments	Investigation|Project administration	YES
2526084	18700024	CAB	2	participated in the design of the study, interpretation of the results, and preparation of the manuscript	participated in the design of the study, interpretation of the results, and preparation of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
2526084	18700024	DEW	2	participated in coordination of the study, provided the equipment used in the study and provided important revisions to the manuscript	participated in coordination of the study, provided the equipment used in the study and provided important revisions to the manuscript	Contributed reagents/materials/analysis tools|Wrote the paper	Project administration|Resources|Writing - Review & Editing	YES
2526084	18700024	JMS	2	participated in acquisition of data and helped organize the study	participated in acquisition of data and helped organize the study	Performed the experiments	Investigation|Project administration	YES
2526084	18700024	MDK	2	designed the study, coordinated the study, acquired the data, performed the statistical analysis, and drafted the manuscript	designed the study, coordinated the study, acquired the data, performed the statistical analysis, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Project administration|Writing - Original Draft	YES
2526084	18700024	MJH	2	participated in the design of the study, interpretation of the results, and preparation of the manuscript	participated in the design of the study, interpretation of the results, and preparation of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4185085	25280865	ACG	2	contributed to the design of the clinical study|contributed to the immune analysis and interpretation of the immune data|contributed to the manuscript writing	contributed to the design of the clinical study	Conceived and designed the experiments	Methodology	YES
4185085	25280865	ACG	2	contributed to the design of the clinical study|contributed to the immune analysis and interpretation of the immune data|contributed to the manuscript writing	contributed to the immune analysis and interpretation of the immune data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
4185085	25280865	ACG	2	contributed to the design of the clinical study|contributed to the immune analysis and interpretation of the immune data|contributed to the manuscript writing	contributed to the manuscript writing	Wrote the paper	Writing - Original Draft	YES
4185085	25280865	AGC	2	contributed to the implementation of the clinical protocol	contributed to the implementation of the clinical protocol	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4185085	25280865	AL	2	contributed to the implementation of the clinical protocol	contributed to the implementation of the clinical protocol	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4185085	25280865	All authors	2	revised and approved the final manuscript	revised and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4185085	25280865	BT	2	contributed to the design of the clinical study|contributed to the implementation of the clinical protocol|contributed to the immune analysis and interpretation of the immune data|contributed to the manuscript writing	contributed to the design of the clinical study	Conceived and designed the experiments	Methodology	YES
4185085	25280865	BT	2	contributed to the design of the clinical study|contributed to the implementation of the clinical protocol|contributed to the immune analysis and interpretation of the immune data|contributed to the manuscript writing	contributed to the implementation of the clinical protocol	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4185085	25280865	BT	2	contributed to the design of the clinical study|contributed to the implementation of the clinical protocol|contributed to the immune analysis and interpretation of the immune data|contributed to the manuscript writing	contributed to the immune analysis and interpretation of the immune data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
4185085	25280865	BT	2	contributed to the design of the clinical study|contributed to the implementation of the clinical protocol|contributed to the immune analysis and interpretation of the immune data|contributed to the manuscript writing	contributed to the manuscript writing	Wrote the paper	Writing - Original Draft	YES
4185085	25280865	CL	2	contributed to the implementation of the clinical protocol	contributed to the implementation of the clinical protocol	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4185085	25280865	FG	2	contributed to the design of the clinical study|contributed to the implementation of the clinical protocol|contributed to the immune analysis and interpretation of the immune data|contributed to the manuscript writing	contributed to the design of the clinical study	Conceived and designed the experiments	Methodology	YES
4185085	25280865	FG	2	contributed to the design of the clinical study|contributed to the implementation of the clinical protocol|contributed to the immune analysis and interpretation of the immune data|contributed to the manuscript writing	contributed to the implementation of the clinical protocol	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4185085	25280865	FG	2	contributed to the design of the clinical study|contributed to the implementation of the clinical protocol|contributed to the immune analysis and interpretation of the immune data|contributed to the manuscript writing	contributed to the immune analysis and interpretation of the immune data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
4185085	25280865	FG	2	contributed to the design of the clinical study|contributed to the implementation of the clinical protocol|contributed to the immune analysis and interpretation of the immune data|contributed to the manuscript writing	contributed to the manuscript writing	Wrote the paper	Writing - Original Draft	YES
4185085	25280865	JMG	2	contributed to the design of the clinical study|contributed to the manuscript writing	contributed to the design of the clinical study	Conceived and designed the experiments	Methodology	YES
4185085	25280865	JMG	2	contributed to the design of the clinical study|contributed to the manuscript writing	contributed to the manuscript writing	Wrote the paper	Writing - Original Draft	YES
4185085	25280865	JV	2	contributed to the immune analysis and interpretation of the immune data	contributed to the immune analysis and interpretation of the immune data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
4185085	25280865	LL	2	contributed to the implementation of the clinical protocol	contributed to the implementation of the clinical protocol	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4185085	25280865	MJAM	2	contributed to the immune analysis and interpretation of the immune data	contributed to the immune analysis and interpretation of the immune data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
4185085	25280865	MM	2	contributed to the immune analysis and interpretation of the immune data	contributed to the immune analysis and interpretation of the immune data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
4185085	25280865	MMR	2	contributed to the implementation of the clinical protocol	contributed to the implementation of the clinical protocol	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4185085	25280865	MP	2	contributed to the design of the clinical study|contributed to the immune analysis and interpretation of the immune data|contributed to the manuscript writing	contributed to the design of the clinical study	Conceived and designed the experiments	Methodology	YES
4185085	25280865	MP	2	contributed to the design of the clinical study|contributed to the immune analysis and interpretation of the immune data|contributed to the manuscript writing	contributed to the immune analysis and interpretation of the immune data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
4185085	25280865	MP	2	contributed to the design of the clinical study|contributed to the immune analysis and interpretation of the immune data|contributed to the manuscript writing	contributed to the manuscript writing	Wrote the paper	Writing - Original Draft	YES
3373154	22701354	A. P. Mansur	2	made substantial contributions to conception, design, analysis and interpretation of data	made substantial contributions to conception, design, analysis and interpretation of data	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Resources	YES
3373154	22701354	All authors	2	were involved in revising the drafts critically for important intellectual content and gave final approval of the version to be published	were involved in revising the drafts critically for important intellectual content and gave final approval of the version to be published	Wrote the paper	Writing - Original Draft	YES
3373154	22701354	C. M. C. Strunz	2	made substantial contributions to the design of the study and drafted the first version of the paper	made substantial contributions to the design of the study and drafted the first version of the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3373154	22701354	J. A. F. Ramires	2	made substantial contributions to the design of the study and drafted the first version of the paper	made substantial contributions to the design of the study and drafted the first version of the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3373154	22701354	J. M. Aldrighi	2	made substantial contributions to the design of the study and drafted the first version of the paper	made substantial contributions to the design of the study and drafted the first version of the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3373154	22701354	J. Y. Takada	2	made substantial contributions to conception, design, analysis and interpretation of data	made substantial contributions to conception, design, analysis and interpretation of data	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Resources	YES
3373154	22701354	L. A. M. Cesar	2	made substantial contributions to the design of the study and drafted the first version of the paper	made substantial contributions to the design of the study and drafted the first version of the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3373154	22701354	S. D. Avakian	2	made substantial contributions to conception, design, analysis and interpretation of data	made substantial contributions to conception, design, analysis and interpretation of data	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Resources	YES
3373154	22701354	T. C. B. F.	2	made substantial contributions to conception, design, analysis and interpretation of data	made substantial contributions to conception, design, analysis and interpretation of data	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Resources	YES
4401566	25884221	AM	PLoS5	Analyzed the data|Critically revised the manuscript and approved the final version	Analyzed the data	Analyzed the data	Formal analysis	YES
4401566	25884221	AM	PLoS5	Analyzed the data|Critically revised the manuscript and approved the final version	Critically revised the manuscript and approved the final version	Wrote the paper	Writing - Review & Editing	YES
4401566	25884221	DP	PLoS5	Analyzed the data|Wrote the paper|Critically revised the manuscript and approved the final version	Analyzed the data	Analyzed the data	Formal analysis	YES
4401566	25884221	DP	PLoS5	Analyzed the data|Wrote the paper|Critically revised the manuscript and approved the final version	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401566	25884221	DP	PLoS5	Analyzed the data|Wrote the paper|Critically revised the manuscript and approved the final version	Critically revised the manuscript and approved the final version	Wrote the paper	Writing - Review & Editing	YES
4401566	25884221	GL	PLoS5	Analyzed the data|Critically revised the manuscript and approved the final version	Analyzed the data	Analyzed the data	Formal analysis	YES
4401566	25884221	GL	PLoS5	Analyzed the data|Critically revised the manuscript and approved the final version	Critically revised the manuscript and approved the final version	Wrote the paper	Writing - Review & Editing	YES
4401566	25884221	JMRG	PLoS5	Conceived and designed the experiments|Analyzed the data|Critically revised the manuscript and approved the final version	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401566	25884221	JMRG	PLoS5	Conceived and designed the experiments|Analyzed the data|Critically revised the manuscript and approved the final version	Analyzed the data	Analyzed the data	Formal analysis	YES
4401566	25884221	JMRG	PLoS5	Conceived and designed the experiments|Analyzed the data|Critically revised the manuscript and approved the final version	Critically revised the manuscript and approved the final version	Wrote the paper	Writing - Review & Editing	YES
4401566	25884221	JW	PLoS5	Performed the experiments|Critically revised the manuscript and approved the final version	Performed the experiments	Performed the experiments	Investigation	YES
4401566	25884221	JW	PLoS5	Performed the experiments|Critically revised the manuscript and approved the final version	Critically revised the manuscript and approved the final version	Wrote the paper	Writing - Review & Editing	YES
4401566	25884221	KAD	PLoS5	Analyzed the data|Critically revised the manuscript and approved the final version	Analyzed the data	Analyzed the data	Formal analysis	YES
4401566	25884221	KAD	PLoS5	Analyzed the data|Critically revised the manuscript and approved the final version	Critically revised the manuscript and approved the final version	Wrote the paper	Writing - Review & Editing	YES
4401566	25884221	NG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Critically revised the manuscript and approved the final version	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401566	25884221	NG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Critically revised the manuscript and approved the final version	Performed the experiments	Performed the experiments	Investigation	YES
4401566	25884221	NG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Critically revised the manuscript and approved the final version	Analyzed the data	Analyzed the data	Formal analysis	YES
4401566	25884221	NG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Critically revised the manuscript and approved the final version	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401566	25884221	NG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Critically revised the manuscript and approved the final version	Critically revised the manuscript and approved the final version	Wrote the paper	Writing - Review & Editing	YES
4401566	25884221	NS	PLoS5	Conceived and designed the experiments|Analyzed the data|Critically revised the manuscript and approved the final version	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401566	25884221	NS	PLoS5	Conceived and designed the experiments|Analyzed the data|Critically revised the manuscript and approved the final version	Analyzed the data	Analyzed the data	Formal analysis	YES
4401566	25884221	NS	PLoS5	Conceived and designed the experiments|Analyzed the data|Critically revised the manuscript and approved the final version	Critically revised the manuscript and approved the final version	Wrote the paper	Writing - Review & Editing	YES
2890504	20525234	AB	2	collected csf samples and made the subject evaluations	collected csf samples and made the subject evaluations	Performed the experiments	Investigation	YES
2890504	20525234	BJB	2	collected csf samples and made the subject evaluations	collected csf samples and made the subject evaluations	Performed the experiments	Investigation	YES
2890504	20525234	DF	2	were responsible for the biochemical analyses	were responsible for the biochemical analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
2890504	20525234	LH	2	collected csf samples and made the subject evaluations|prepared the manuscript	collected csf samples and made the subject evaluations	Performed the experiments	Investigation	YES
2890504	20525234	LH	2	collected csf samples and made the subject evaluations|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
2890504	20525234	MG	2	collected csf samples and made the subject evaluations	collected csf samples and made the subject evaluations	Performed the experiments	Investigation	YES
2890504	20525234	PC	2	collected csf samples and made the subject evaluations	collected csf samples and made the subject evaluations	Performed the experiments	Investigation	YES
2890504	20525234	RWP	2	collected csf samples and made the subject evaluations|were responsible for the biochemical analyses|prepared the manuscript	collected csf samples and made the subject evaluations	Performed the experiments	Investigation	YES
2890504	20525234	RWP	2	collected csf samples and made the subject evaluations|were responsible for the biochemical analyses|prepared the manuscript	were responsible for the biochemical analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
2890504	20525234	RWP	2	collected csf samples and made the subject evaluations|were responsible for the biochemical analyses|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
2890504	20525234	SS	2	collected csf samples and made the subject evaluations	collected csf samples and made the subject evaluations	Performed the experiments	Investigation	YES
5476930	28676804	CF	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
5476930	28676804	DH	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
5476930	28676804	JG	PLoS52	performed research|analyzed data	performed research	Performed the experiments	Investigation	YES
5476930	28676804	JG	PLoS52	performed research|analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5476930	28676804	LS	PLoS52	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5476930	28676804	SL	PLoS52	designed research|performed research|analyzed data|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
5476930	28676804	SL	PLoS52	designed research|performed research|analyzed data|wrote the paper	performed research	Performed the experiments	Investigation	YES
5476930	28676804	SL	PLoS52	designed research|performed research|analyzed data|wrote the paper	analyzed data	Analyzed the data	Formal analysis	YES
5476930	28676804	SL	PLoS52	designed research|performed research|analyzed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5476930	28676804	YZ	PLoS52	designed research|analyzed data|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
5476930	28676804	YZ	PLoS52	designed research|analyzed data|wrote the paper	analyzed data	Analyzed the data	Formal analysis	YES
5476930	28676804	YZ	PLoS52	designed research|analyzed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5476930	28676804	Z-YW	PLoS52	designed research|analyzed data|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
5476930	28676804	Z-YW	PLoS52	designed research|analyzed data|wrote the paper	analyzed data	Analyzed the data	Formal analysis	YES
5476930	28676804	Z-YW	PLoS52	designed research|analyzed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4186673	25226090	E.M.G.	2	contributed equally	contributed equally	-	-	NO
4186673	25226090	S.M.	2	contributed equally	contributed equally	-	-	NO
4444569	26075280	Changhong Ke	2	contributed equally	contributed equally	-	-	NO
4444569	26075280	Feng Chen	2	contributed equally	contributed equally	-	-	NO
4444569	26075280	Lin Chen	2	contributed equally	contributed equally	-	-	NO
4444569	26075280	Mengxin Zhao	2	contributed equally	contributed equally	-	-	NO
4444569	26075280	Xiandi Zhu	2	contributed equally	contributed equally	-	-	NO
5109742	27842489	BL	2	conceived the study|performed bioinformatics	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5109742	27842489	BL	2	conceived the study|performed bioinformatics	performed bioinformatics	Performed the experiments	Formal analysis|Investigation	YES
5109742	27842489	DO	2	conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5109742	27842489	GSP	2	conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5109742	27842489	MD	2	conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
2894737	20507622	ACW	1	The following authors were involved in study conception and design	The following authors were involved in study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
2894737	20507622	BKA	1	The following authors were involved in study conception and design	The following authors were involved in study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
2894737	20507622	GG	1	The following authors were involved in study conception and design	The following authors were involved in study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
2894737	20507622	VCM	1	The following authors were involved in study conception and design	The following authors were involved in study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
2526996	18700045	HW	2	conceived the study, participated in study design, data collection, calculation, and statistical analysis, drafted and revised manuscript	conceived the study, participated in study design, data collection, calculation, and statistical analysis, drafted and revised manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
2526996	18700045	KS	2	conceived the study, participated in study design, helped draft and revise the manuscript, gave final approval of the version to be published	conceived the study, participated in study design, helped draft and revise the manuscript, gave final approval of the version to be published	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
2526996	18700045	OM	2	conceived the study, participated in study design, recruited and assessed potential participants, and helped draft the manuscript	conceived the study, participated in study design, recruited and assessed potential participants, and helped draft the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Writing - Original Draft	YES
2526996	18700045	SC	2	participated in data acquisition and helped draft the manuscript	participated in data acquisition and helped draft the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
2526996	18700045	TK	2	participated in study design and coordination, recruited and assessed potential participants and helped draft the manuscript	participated in study design and coordination, recruited and assessed potential participants and helped draft the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Project administration|Writing - Original Draft	YES
4401567	25885260	CJK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Reviewed and approved the final manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401567	25885260	CJK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Reviewed and approved the final manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4401567	25885260	CJK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Reviewed and approved the final manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4401567	25885260	CJK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Reviewed and approved the final manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401567	25885260	CJK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Reviewed and approved the final manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401567	25885260	CJK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Reviewed and approved the final manuscript	Reviewed and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4401567	25885260	JLS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Reviewed and approved the final manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401567	25885260	JLS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Reviewed and approved the final manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4401567	25885260	JLS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Reviewed and approved the final manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4401567	25885260	JLS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Reviewed and approved the final manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401567	25885260	JLS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Reviewed and approved the final manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401567	25885260	JLS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Reviewed and approved the final manuscript	Reviewed and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4401567	25885260	WML	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper|Reviewed and approved the final manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401567	25885260	WML	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper|Reviewed and approved the final manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401567	25885260	WML	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper|Reviewed and approved the final manuscript	Reviewed and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5476934	28676819	All authors	2	were involved with the revision of the manuscript and approved the final manuscript	were involved with the revision of the manuscript and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5476934	28676819	QS	2	designed the study, and organized all the data and wrote the manuscript	designed the study, and organized all the data and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft	YES
5476934	28676819	RL	2	performed sample collection, mrna quantification and physiological experiments	performed sample collection, mrna quantification and physiological experiments	Performed the experiments	Investigation	YES
5476934	28676819	RW	2	performed sample collection, mrna quantification and physiological experiments	performed sample collection, mrna quantification and physiological experiments	Performed the experiments	Investigation	YES
5476934	28676819	SD	2	designed the study, and organized all the data and wrote the manuscript	designed the study, and organized all the data and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft	YES
5476934	28676819	ST	2	performed sample collection, mrna quantification and physiological experiments	performed sample collection, mrna quantification and physiological experiments	Performed the experiments	Investigation	YES
5476934	28676819	SX	2	performed proteomic data analysis|designed the study, and organized all the data and wrote the manuscript	performed proteomic data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5476934	28676819	SX	2	performed proteomic data analysis|designed the study, and organized all the data and wrote the manuscript	designed the study, and organized all the data and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft	YES
5476934	28676819	WZ	2	performed proteomic data analysis	performed proteomic data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5476934	28676819	XW	2	performed proteomic data analysis	performed proteomic data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5476934	28676819	YL	2	performed proteomic data analysis|performed sample collection, mrna quantification and physiological experiments|designed the study, and organized all the data and wrote the manuscript	performed proteomic data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5476934	28676819	YL	2	performed proteomic data analysis|performed sample collection, mrna quantification and physiological experiments|designed the study, and organized all the data and wrote the manuscript	performed sample collection, mrna quantification and physiological experiments	Performed the experiments	Investigation	YES
5476934	28676819	YL	2	performed proteomic data analysis|performed sample collection, mrna quantification and physiological experiments|designed the study, and organized all the data and wrote the manuscript	designed the study, and organized all the data and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft	YES
4444570	26075257	Fuminori Sakurai	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
4444570	26075257	Shunsuke Iizuka	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
2895573	20546571	CC	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
2895573	20546571	GV	PLoS52	participated in the design and coordination of the study and helped draft the manuscript	participated in the design and coordination of the study and helped draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft	YES
2895573	20546571	HB	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
2895573	20546571	HS	PLoS52	performed the experiments|analyzed data and wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
2895573	20546571	HS	PLoS52	performed the experiments|analyzed data and wrote the paper	analyzed data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
2895573	20546571	LB	PLoS52	analyzed data and wrote the paper|conceived the study, participated in its design and coordination, analyzed data and wrote the paper	analyzed data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
2895573	20546571	LB	PLoS52	analyzed data and wrote the paper|conceived the study, participated in its design and coordination, analyzed data and wrote the paper	conceived the study, participated in its design and coordination, analyzed data and wrote the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Project administration|Writing - Original Draft	YES
2895573	20546571	MAJ	PLoS52	performed the experiments|analyzed data and wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
2895573	20546571	MAJ	PLoS52	performed the experiments|analyzed data and wrote the paper	analyzed data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
2895573	20546571	TWB	PLoS52	provided cada and helped draft the manuscript	provided cada and helped draft the manuscript	Wrote the paper	Writing - Original Draft	YES
4401568	25885059	BH	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401568	25885059	BH	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401568	25885059	JF	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401568	25885059	JL	PLoS5	Provided constructive advice in manuscript preparation	Provided constructive advice in manuscript preparation	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4401568	25885059	WY	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401568	25885059	YC	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401568	25885059	YC	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401568	25885059	YL	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401568	25885059	YL	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401568	25885059	YZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
2542988	18783626	AS	2	contributed in writing and editing the manuscript along with concept and design, data acquisition, and data analysis and interpretation	contributed in writing and editing the manuscript along with concept and design, data acquisition, and data analysis and interpretation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
2542988	18783626	AW	2	contributed in concept and design, data acquisition, and data analysis and interpretation	contributed in concept and design, data acquisition, and data analysis and interpretation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
2542988	18783626	CL	2	contributed in concept and design, data acquisition, and data analysis and interpretation	contributed in concept and design, data acquisition, and data analysis and interpretation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
2542988	18783626	JC	2	contributed in writing and editing the manuscript, as well as concept and design	contributed in writing and editing the manuscript, as well as concept and design	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
2542988	18783626	JG	2	contributed in writing and editing the manuscript along with concept and design, data acquisition, and data analysis and interpretation	contributed in writing and editing the manuscript along with concept and design, data acquisition, and data analysis and interpretation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
2542988	18783626	JM	2	contributed in writing and editing the manuscript, as well as concept and design	contributed in writing and editing the manuscript, as well as concept and design	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
2542988	18783626	JS	2	contributed in writing and editing the manuscript, as well as concept and design	contributed in writing and editing the manuscript, as well as concept and design	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
2542988	18783626	KK	2	contributed in writing and editing the manuscript along with concept and design, data acquisition, and data analysis and interpretation	contributed in writing and editing the manuscript along with concept and design, data acquisition, and data analysis and interpretation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
2542988	18783626	TB	2	contributed in writing and editing the manuscript, as well as concept and design	contributed in writing and editing the manuscript, as well as concept and design	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
4188039	25103308	BXW	2	participated in study concept and design, interpretation of the results and supervision	participated in study concept and design, interpretation of the results and supervision	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology|Supervision	YES
4188039	25103308	BY	2	supervised the study procedures on site and provided data	supervised the study procedures on site and provided data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources|Supervision	YES
4188039	25103308	GJL	2	participated in study concept and design, interpretation of the results and supervision	participated in study concept and design, interpretation of the results and supervision	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology|Supervision	YES
4188039	25103308	NJ	2	is the coordinator of the project	is the coordinator of the project	-	Project administration	YES
4188039	25103308	QL	2	supervised the study procedures on site and provided data	supervised the study procedures on site and provided data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources|Supervision	YES
4188039	25103308	QQW	2	had full access to all of the data in the study and takes responsibility for the integrity of the data|participated in study concept and design, interpretation of the results and supervision|were responsible for data analysis and manuscript drafting	had full access to all of the data in the study and takes responsibility for the integrity of the data	-	Data curation	YES
4188039	25103308	QQW	2	had full access to all of the data in the study and takes responsibility for the integrity of the data|participated in study concept and design, interpretation of the results and supervision|were responsible for data analysis and manuscript drafting	participated in study concept and design, interpretation of the results and supervision	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology|Supervision	YES
4188039	25103308	QQW	2	had full access to all of the data in the study and takes responsibility for the integrity of the data|participated in study concept and design, interpretation of the results and supervision|were responsible for data analysis and manuscript drafting	were responsible for data analysis and manuscript drafting	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4188039	25103308	RLZ	2	were responsible for data analysis and manuscript drafting	were responsible for data analysis and manuscript drafting	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4188039	25103308	XPH	2	supervised the study procedures on site and provided data	supervised the study procedures on site and provided data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources|Supervision	YES
4188039	25103308	XSC	2	participated in study concept and design, interpretation of the results and supervision	participated in study concept and design, interpretation of the results and supervision	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology|Supervision	YES
4188039	25103308	YJZ	2	supervised the study procedures on site and provided data	supervised the study procedures on site and provided data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources|Supervision	YES
4188039	25103308	YPY	2	provided laboratory support for the project	provided laboratory support for the project	-	-	NO
5109749	27846797	A.K.M.	2	analysed the data and performed bioinformatics and experimental work|wrote the manuscript	analysed the data and performed bioinformatics and experimental work	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5109749	27846797	A.K.M.	2	analysed the data and performed bioinformatics and experimental work|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5109749	27846797	B.J.	2	provided the cbcvd-infected and healthy hop plant material|supervised the research work	provided the cbcvd-infected and healthy hop plant material	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5109749	27846797	B.J.	2	provided the cbcvd-infected and healthy hop plant material|supervised the research work	supervised the research work	Performed the experiments	Investigation|Supervision	YES
5109749	27846797	G.S.D.	2	analysed the data and performed bioinformatics and experimental work	analysed the data and performed bioinformatics and experimental work	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5109749	27846797	J.J.	2	analysed the data and performed bioinformatics and experimental work	analysed the data and performed bioinformatics and experimental work	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5109749	27846797	J.M.	2	supervised the research work	supervised the research work	Performed the experiments	Investigation|Supervision	YES
5109749	27846797	S.R.	2	provided the cbcvd-infected and healthy hop plant material	provided the cbcvd-infected and healthy hop plant material	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5476935	28676805	RC	2	wrote the review	wrote the review	Wrote the paper	Writing - Original Draft	YES
5476935	28676805	RDT	2	conceptualized the review	conceptualized the review	Conceived and designed the experiments	Conceptualization	YES
5476935	28676805	SA	2	wrote the review	wrote the review	Wrote the paper	Writing - Original Draft	YES
5476935	28676805	SS	2	conceptualized the review|wrote the review	conceptualized the review	Conceived and designed the experiments	Conceptualization	YES
5476935	28676805	SS	2	conceptualized the review|wrote the review	wrote the review	Wrote the paper	Writing - Original Draft	YES
2898658	20500901	ART	2	clinics, conducted statistical analysis and reviewed the manuscript|clinics, data analysis, and review of manuscript	clinics, conducted statistical analysis and reviewed the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
2898658	20500901	ART	2	clinics, conducted statistical analysis and reviewed the manuscript|clinics, data analysis, and review of manuscript	clinics, data analysis, and review of manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
2898658	20500901	CS	2	was involved in conceiving the study design, conducted data capture from clinical and laboratory records, analysed data and wrote the first draft of the manuscript	was involved in conceiving the study design, conducted data capture from clinical and laboratory records, analysed data and wrote the first draft of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
2898658	20500901	DS	2	was involved in conception of study design, data capturing, and review of manuscript	was involved in conception of study design, data capturing, and review of manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
2898658	20500901	GM	2	was responsible for conception of study design, supervised the study and reviewed the manuscript	was responsible for conception of study design, supervised the study and reviewed the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Supervision|Writing - Review & Editing	YES
2898658	20500901	KR	2	provided clinical support and advice and reviewed manuscript	provided clinical support and advice and reviewed manuscript	Wrote the paper	Writing - Review & Editing	YES
2551586	18775082	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
2551586	18775082	CVD	2	before and after training	before and after training	-	-	NO
2551586	18775082	EHS	2	participated in preparation of the study design, conducted experiments and exercise training, and participated in writing the manuscript	participated in preparation of the study design, conducted experiments and exercise training, and participated in writing the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
2551586	18775082	GS	2	maintained regulatory compliance and performed immunoassay of serum samples, and performed data analysis	maintained regulatory compliance and performed immunoassay of serum samples, and performed data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
2551586	18775082	JC	2	maintained regulatory compliance, administered the budget, and participated in data analysis and writing sections of the manuscript	maintained regulatory compliance, administered the budget, and participated in data analysis and writing sections of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
2551586	18775082	KM	2	conceived of the study and participated in its design and coordination, and in writing the manuscript	conceived of the study and participated in its design and coordination, and in writing the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
2551586	18775082	MJS	2	conceived of the study, conducted and coordinated the experiments, performed data analysis, and drafted the manuscript	conceived of the study, conducted and coordinated the experiments, performed data analysis, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Project administration|Writing - Original Draft	YES
2551586	18775082	RL	2	participated in the preparation of the study design and in writing the manuscript	participated in the preparation of the study design and in writing the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
2551586	18775082	SD	2	for the other data	for the other data	-	-	NO
4401569	25884705	AM-F	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401569	25884705	AM-F	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401569	25884705	AM-F	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401569	25884705	AM-F	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401569	25884705	CB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401569	25884705	CB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401569	25884705	CB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401569	25884705	JG-M	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401569	25884705	JG-M	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401569	25884705	JG-M	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401569	25884705	JP-O	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401569	25884705	JP-O	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401569	25884705	JP-O	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401569	25884705	JP-O	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4189018	25292158	BT	2	checked scientific soundness and reviewed the manuscript several times	checked scientific soundness and reviewed the manuscript several times	Wrote the paper	Writing - Review & Editing	YES
4189018	25292158	DR	2	checked scientific soundness and reviewed the manuscript several times	checked scientific soundness and reviewed the manuscript several times	Wrote the paper	Writing - Review & Editing	YES
4189018	25292158	FL	2	checked scientific soundness and reviewed the manuscript several times	checked scientific soundness and reviewed the manuscript several times	Wrote the paper	Writing - Review & Editing	YES
4189018	25292158	FR	2	conceptualized the study and wrote a first draft, which was edited by all authors|finalized the manuscript	conceptualized the study and wrote a first draft, which was edited by all authors	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
4189018	25292158	FR	2	conceptualized the study and wrote a first draft, which was edited by all authors|finalized the manuscript	finalized the manuscript	Wrote the paper	Writing - Review & Editing	YES
4189018	25292158	MB	2	checked scientific soundness and reviewed the manuscript several times	checked scientific soundness and reviewed the manuscript several times	Wrote the paper	Writing - Review & Editing	YES
4189018	25292158	TD	2	checked scientific soundness and reviewed the manuscript several times|finalized the manuscript	checked scientific soundness and reviewed the manuscript several times	Wrote the paper	Writing - Review & Editing	YES
4189018	25292158	TD	2	checked scientific soundness and reviewed the manuscript several times|finalized the manuscript	finalized the manuscript	Wrote the paper	Writing - Review & Editing	YES
4189018	25292158	WVD	2	checked scientific soundness and reviewed the manuscript several times	checked scientific soundness and reviewed the manuscript several times	Wrote the paper	Writing - Review & Editing	YES
5477006	28676813	CC	2	designed and wrote the manuscript	designed and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
5477006	28676813	CR	2	designed and wrote the manuscript	designed and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
5477006	28676813	PF	2	designed and wrote the manuscript	designed and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
5477006	28676813	TC	2	designed and wrote the manuscript	designed and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
4401571	25884947	AN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401571	25884947	AN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401571	25884947	AN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401571	25884947	AN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401571	25884947	AN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401571	25884947	CN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401571	25884947	CN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401571	25884947	CN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401571	25884947	CN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401571	25884947	CN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401571	25884947	KL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401571	25884947	KL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401571	25884947	KL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401571	25884947	KL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401571	25884947	KL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401571	25884947	PY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401571	25884947	PY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401571	25884947	PY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401571	25884947	PY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401571	25884947	PY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401571	25884947	VEK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401571	25884947	VEK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401571	25884947	VEK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401571	25884947	VEK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401571	25884947	VEK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5109768	27842493	CE	PLoS52	conceived and designed the experiments|analyzed the data|contributed reagents/materials/analysis tools|contributed to the writing of the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5109768	27842493	CE	PLoS52	conceived and designed the experiments|analyzed the data|contributed reagents/materials/analysis tools|contributed to the writing of the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5109768	27842493	CE	PLoS52	conceived and designed the experiments|analyzed the data|contributed reagents/materials/analysis tools|contributed to the writing of the manuscript	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5109768	27842493	CE	PLoS52	conceived and designed the experiments|analyzed the data|contributed reagents/materials/analysis tools|contributed to the writing of the manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5109768	27842493	FR	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5109768	27842493	LC	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|contributed to the writing of the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5109768	27842493	LC	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|contributed to the writing of the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5109768	27842493	LC	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|contributed to the writing of the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5109768	27842493	LC	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|contributed to the writing of the manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5109768	27842493	LP	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|contributed reagents/materials/analysis tools|contributed to the writing of the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5109768	27842493	LP	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|contributed reagents/materials/analysis tools|contributed to the writing of the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5109768	27842493	LP	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|contributed reagents/materials/analysis tools|contributed to the writing of the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5109768	27842493	LP	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|contributed reagents/materials/analysis tools|contributed to the writing of the manuscript	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5109768	27842493	LP	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|contributed reagents/materials/analysis tools|contributed to the writing of the manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5109768	27842493	MG	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
2551587	18782456	JAH	2	conceived the study and secured the research funding	conceived the study and secured the research funding	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
2551587	18782456	JMS	2	helped recruit the subjects and collect the data	helped recruit the subjects and collect the data	Performed the experiments	Investigation	YES
2551587	18782456	LCG	2	conceived the study and secured the research funding|analysed and interpreted the data	conceived the study and secured the research funding	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
2551587	18782456	LCG	2	conceived the study and secured the research funding|analysed and interpreted the data	analysed and interpreted the data	Analyzed the data	Formal analysis	YES
2551587	18782456	MC	2	conceived the study and secured the research funding	conceived the study and secured the research funding	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
2551587	18782456	MDM	2	conceived the study and secured the research funding	conceived the study and secured the research funding	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
2551587	18782456	SMG	2	analysed and interpreted the data|wrote the original draft of the manuscript which was then reviewed and edited by all authors	analysed and interpreted the data	Analyzed the data	Formal analysis	YES
2551587	18782456	SMG	2	analysed and interpreted the data|wrote the original draft of the manuscript which was then reviewed and edited by all authors	wrote the original draft of the manuscript which was then reviewed and edited by all authors	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3373177	22701359	F. Takatsu	2	performed data collection	performed data collection	Performed the experiments	Investigation	YES
3373177	22701359	H. Morimatsu	2	conceived the study, participated in its design, and drafted paper	conceived the study, participated in its design, and drafted paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
3373177	22701359	K. Morita	2	revised the paper for intellectual content	revised the paper for intellectual content	Wrote the paper	Writing - Review & Editing	YES
3373177	22701359	M. Tani	2	analysed the data and drafted the paper	analysed the data and drafted the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
2898659	20565763	AA	2	participated in the development of the methodology, analyzed the data, and developed the manuscript	participated in the development of the methodology, analyzed the data, and developed the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
2898659	20565763	CY	2	participated in the development of the methodology and collected data	participated in the development of the methodology and collected data	Performed the experiments	Investigation|Methodology	YES
2898659	20565763	GW	2	participated in the development of the methodology and collected data	participated in the development of the methodology and collected data	Performed the experiments	Investigation|Methodology	YES
2898659	20565763	JH	2	participated in the development of the methodology and collected data	participated in the development of the methodology and collected data	Performed the experiments	Investigation|Methodology	YES
2898659	20565763	LZ	2	participated in the development of the methodology, and collected and analyzed data|participated in the development of the methodology and collected data	participated in the development of the methodology, and collected and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
2898659	20565763	LZ	2	participated in the development of the methodology, and collected and analyzed data|participated in the development of the methodology and collected data	participated in the development of the methodology and collected data	Performed the experiments	Investigation|Methodology	YES
2898659	20565763	MX	2	participated in the development of the methodology, collected data, analyzed data, and developed the manuscript	participated in the development of the methodology, collected data, analyzed data, and developed the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
2898659	20565763	WL	2	participated in the development of the methodology and collected data	participated in the development of the methodology and collected data	Performed the experiments	Investigation|Methodology	YES
5477293	28676807	AW	2	wrote the manuscript|revised it	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5477293	28676807	AW	2	wrote the manuscript|revised it	revised it	Wrote the paper	Writing - Review & Editing	YES
5477293	28676807	RN	2	wrote the manuscript|revised it	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5477293	28676807	RN	2	wrote the manuscript|revised it	revised it	Wrote the paper	Writing - Review & Editing	YES
5477293	28676807	RS	2	wrote the manuscript|revised it	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5477293	28676807	RS	2	wrote the manuscript|revised it	revised it	Wrote the paper	Writing - Review & Editing	YES
5477293	28676807	SM	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5477293	28676807	VB	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4401572	25884801	CL	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401572	25884801	CW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401572	25884801	JZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401572	25884801	LX	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401572	25884801	LX	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401572	25884801	LZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401572	25884801	PY	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401572	25884801	PY	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401572	25884801	RC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401572	25884801	SZ	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401572	25884801	XW	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401572	25884801	XW	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401572	25884801	XY	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401572	25884801	YD	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401572	25884801	ZZ	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4401572	25884801	ZZ	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5109822	27842488	CL	2	performed the experiments and wrote the paper	performed the experiments and wrote the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5109822	27842488	CX	2	performed the experiments and wrote the paper|designed the experiments	performed the experiments and wrote the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5109822	27842488	CX	2	performed the experiments and wrote the paper|designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5109822	27842488	FL	2	performed the experiments and revised the paper	performed the experiments and revised the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5109822	27842488	HW	2	performed the experiments and revised the paper	performed the experiments and revised the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5109822	27842488	JW	2	performed the experiments and revised the paper	performed the experiments and revised the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5109822	27842488	LD	2	performed the experiments and wrote the paper	performed the experiments and wrote the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5109822	27842488	QZ	2	performed the experiments and wrote the paper	performed the experiments and wrote the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5109822	27842488	XL	2	performed the experiments and revised the paper	performed the experiments and revised the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
2898660	20569473	JA	2	gave scientific input and edited the manuscript	gave scientific input and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
2898660	20569473	RR	2	reviewed the literature and drafted the manuscript	reviewed the literature and drafted the manuscript	Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
4192834	25301494	All authors	2	contributed to the writing of the manuscript and approved the final version	contributed to the writing of the manuscript and approved the final version	Wrote the paper	Writing - Original Draft	YES
4192834	25301494	EJA	2	were involved in reviewing the manuscript	were involved in reviewing the manuscript	Wrote the paper	Writing - Review & Editing	YES
4192834	25301494	ET	2	was involved in data collection and reviewing the manuscript	was involved in data collection and reviewing the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4192834	25301494	JM	2	was involved in developing the study proposal and reviewing the manuscript	was involved in developing the study proposal and reviewing the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4192834	25301494	LGB	2	were involved in reviewing the manuscript	were involved in reviewing the manuscript	Wrote the paper	Writing - Review & Editing	YES
4192834	25301494	LM	2	was involved in developing the study proposal, supervising the data collection and analysis, and drafting the manuscript	was involved in developing the study proposal, supervising the data collection and analysis, and drafting the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Supervision|Writing - Original Draft	YES
4192834	25301494	TP	2	prepared the study proposal, collected and analyzed the data, interpreted the findings and drafted the manuscript	prepared the study proposal, collected and analyzed the data, interpreted the findings and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5363288	28207250	P These	2	authors contributed equally to this work	authors contributed equally to this work	-	-	NO
5477294	28676808	AL	2	helped with statistical analysis|edited the manuscript	helped with statistical analysis	Analyzed the data	Formal analysis	YES
5477294	28676808	AL	2	helped with statistical analysis|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5477294	28676808	DS	2	collected genotype and phenotype data for doubled haploids as a comparison	collected genotype and phenotype data for doubled haploids as a comparison	Performed the experiments	Investigation	YES
5477294	28676808	GA	2	inhibitor response	inhibitor response	-	-	NO
5477294	28676808	MB	2	edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5477294	28676808	PL	2	helped with statistical analysis|edited the manuscript	helped with statistical analysis	Analyzed the data	Formal analysis	YES
5477294	28676808	PL	2	helped with statistical analysis|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5477294	28676808	SH	2	conceived the study, designed the experiments, discussed the results and finalized the manuscript	conceived the study, designed the experiments, discussed the results and finalized the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
5477294	28676808	TL	2	conceived the study, designed the experiments, discussed the results and finalized the manuscript|edited the manuscript	conceived the study, designed the experiments, discussed the results and finalized the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
5477294	28676808	TL	2	conceived the study, designed the experiments, discussed the results and finalized the manuscript|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5477294	28676808	YY	2	edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5477294	28676808	all authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4401573	25884952	DX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401573	25884952	DX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401573	25884952	DX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401573	25884952	DX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401573	25884952	DX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401573	25884952	EYW	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401573	25884952	SPP	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401573	25884952	SPP	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2596786	18840293	GH	2	suggested applying the model to data from the minnesota study and discovered the regular relationship between change during weeks 1-12 and 13-24|used these equations to provide all estimates of rate parameters and steady state values by means of the 3 point method|jointly prepared the figures and tables and wrote the manuscript	suggested applying the model to data from the minnesota study and discovered the regular relationship between change during weeks 1-12 and 13-24	Performed the experiments	Methodology	YES
2596786	18840293	GH	2	suggested applying the model to data from the minnesota study and discovered the regular relationship between change during weeks 1-12 and 13-24|used these equations to provide all estimates of rate parameters and steady state values by means of the 3 point method|jointly prepared the figures and tables and wrote the manuscript	used these equations to provide all estimates of rate parameters and steady state values by means of the 3 point method	Performed the experiments|Analyzed the data	Formal analysis	YES
2596786	18840293	GH	2	suggested applying the model to data from the minnesota study and discovered the regular relationship between change during weeks 1-12 and 13-24|used these equations to provide all estimates of rate parameters and steady state values by means of the 3 point method|jointly prepared the figures and tables and wrote the manuscript	jointly prepared the figures and tables and wrote the manuscript	Wrote the paper	Visualization|Writing - Original Draft	YES
2596786	18840293	JLH	2	jointly prepared the figures and tables and wrote the manuscript	jointly prepared the figures and tables and wrote the manuscript	Wrote the paper	Visualization|Writing - Original Draft	YES
2596786	18840293	OH	2	derived equations 5 and 6 to solve for model parameters and contributed extensively to discussions of the model	derived equations 5 and 6 to solve for model parameters and contributed extensively to discussions of the model	Performed the experiments	Methodology	YES
5109826	27846794	LW	2	designed the experiments|performed the proteomic experiments and analyzed the data|prepared the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5109826	27846794	LW	2	designed the experiments|performed the proteomic experiments and analyzed the data|prepared the manuscript	performed the proteomic experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5109826	27846794	LW	2	designed the experiments|performed the proteomic experiments and analyzed the data|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5109826	27846794	MD	2	designed the experiments|performed the manual genome annotation|performed the proteomic experiments and analyzed the data|prepared the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5109826	27846794	MD	2	designed the experiments|performed the manual genome annotation|performed the proteomic experiments and analyzed the data|prepared the manuscript	performed the manual genome annotation	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5109826	27846794	MD	2	designed the experiments|performed the manual genome annotation|performed the proteomic experiments and analyzed the data|prepared the manuscript	performed the proteomic experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5109826	27846794	MD	2	designed the experiments|performed the manual genome annotation|performed the proteomic experiments and analyzed the data|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5109826	27846794	MK	2	performed the genome sequencing|provided bioinformatic expertise	performed the genome sequencing	Performed the experiments	Investigation	YES
5109826	27846794	MK	2	performed the genome sequencing|provided bioinformatic expertise	provided bioinformatic expertise	-	Formal analysis	YES
5109826	27846794	RRa	2	designed the experiments|prepared the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5109826	27846794	RRa	2	designed the experiments|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5109826	27846794	RRe	2	performed the genome sequencing	performed the genome sequencing	Performed the experiments	Investigation	YES
2903493	20579347	OOT	2	conceived the idea, designed the study and wrote the protocol|prepared the recording leaflets, took the digital pictures, entered them in to the computer and performed the analysis|participated in data collection and writing of the manuscript	conceived the idea, designed the study and wrote the protocol	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
2903493	20579347	OOT	2	conceived the idea, designed the study and wrote the protocol|prepared the recording leaflets, took the digital pictures, entered them in to the computer and performed the analysis|participated in data collection and writing of the manuscript	prepared the recording leaflets, took the digital pictures, entered them in to the computer and performed the analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
2903493	20579347	OOT	2	conceived the idea, designed the study and wrote the protocol|prepared the recording leaflets, took the digital pictures, entered them in to the computer and performed the analysis|participated in data collection and writing of the manuscript	participated in data collection and writing of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
2903493	20579347	ZH	2	did the overall supervision, patient coordination and follow - up|participated in data collection and writing of the manuscript	did the overall supervision, patient coordination and follow - up	-	Project administration|Supervision	YES
2903493	20579347	ZH	2	did the overall supervision, patient coordination and follow - up|participated in data collection and writing of the manuscript	participated in data collection and writing of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4401577	25886629	PJC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401577	25886629	PJC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401577	25886629	PJC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401577	25886629	PJC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401577	25886629	PRE	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401577	25886629	PRE	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401577	25886629	PRE	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401577	25886629	TTN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401577	25886629	TTN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401577	25886629	TTN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401577	25886629	TTN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401577	25886629	TTN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5477295	28676816	All authors	2	listed, have made substantial, direct and intellectual contribution to the work, and approved it for publication	listed, have made substantial, direct and intellectual contribution to the work, and approved it for publication	-	-	NO
4195174	25308903	CB	2	assisted in the design of the paper and played a substantial role in the analysis of data|also assisted in the revision of this paper	assisted in the design of the paper and played a substantial role in the analysis of data	Conceived and designed the experiments|Analyzed the data	Formal analysis	YES
4195174	25308903	CB	2	assisted in the design of the paper and played a substantial role in the analysis of data|also assisted in the revision of this paper	also assisted in the revision of this paper	Wrote the paper	Writing - Review & Editing	YES
4195174	25308903	JK	2	played a key role in the development of the design of the paper, guided the analysis and interpretation, and was integral in the revision process	played a key role in the development of the design of the paper, guided the analysis and interpretation, and was integral in the revision process	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
4195174	25308903	JV	2	was primarily responsible for the design of the paper and the acquisition, analysis and interpretation of data, and was the primary researcher involved in the drafting and revision of this manuscript	was primarily responsible for the design of the paper and the acquisition, analysis and interpretation of data, and was the primary researcher involved in the drafting and revision of this manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
2642810	19144121	RB	2	provided figure 1 and assisted with manuscript, as well as table preparation	provided figure 1 and assisted with manuscript, as well as table preparation	Wrote the paper	Visualization|Writing - Original Draft	YES
2908552	20604950	FK	2	provided overall direction and funding for the project	provided overall direction and funding for the project	-	Funding acquisition|Supervision	YES
2908552	20604950	HAART	2	responders, etc	responders, etc	-	-	NO
2908552	20604950	IG	2	performed serum depletion	performed serum depletion	Performed the experiments	Investigation	YES
2908552	20604950	KKH	2	performed the rt and mtt assays	performed the rt and mtt assays	Performed the experiments	Investigation	YES
2908552	20604950	LTNP	2	responders, etc	responders, etc	-	-	NO
2908552	20604950	MALDI	2	preparation, and mass spectrometry analysis as well as the drafting of the manuscript|preparation, and confirmatory western blots	preparation, and mass spectrometry analysis as well as the drafting of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
2908552	20604950	MALDI	2	preparation, and mass spectrometry analysis as well as the drafting of the manuscript|preparation, and confirmatory western blots	preparation, and confirmatory western blots	Performed the experiments	Investigation	YES
2908552	20604950	MY	2	is the wihs contact and provided support and information on patient samples	is the wihs contact and provided support and information on patient samples	Contributed reagents/materials/analysis tools	Resources	YES
2908552	20604950	RE	2	performed the maldi preparation and analysis	performed the maldi preparation and analysis	Performed the experiments	Investigation	YES
2908552	20604950	RVD	2	performed the serum depletion, 2d gel analysis	performed the serum depletion, 2d gel analysis	Performed the experiments	Investigation	YES
2908552	20604950	ZK	2	provided support in drafting the manuscript and maldi analysis	provided support in drafting the manuscript and maldi analysis	Wrote the paper	Writing - Original Draft	YES
5111228	27846799	LB	PLoS52	planned the experiments|provided the funding and helped with the writing	planned the experiments	Conceived and designed the experiments	Conceptualization	YES
5111228	27846799	LB	PLoS52	planned the experiments|provided the funding and helped with the writing	provided the funding and helped with the writing	Wrote the paper	Funding acquisition	YES
5111228	27846799	MN	PLoS52	planned the experiments|did the laboratory work and the analyses|wrote the paper	planned the experiments	Conceived and designed the experiments	Conceptualization	YES
5111228	27846799	MN	PLoS52	planned the experiments|did the laboratory work and the analyses|wrote the paper	did the laboratory work and the analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5111228	27846799	MN	PLoS52	planned the experiments|did the laboratory work and the analyses|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401579	25884501	ACZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401579	25884501	ACZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401579	25884501	ACZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401579	25884501	ACZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401579	25884501	CMF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401579	25884501	CMF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401579	25884501	CMF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401579	25884501	CMF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401579	25884501	KV	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401579	25884501	KV	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401579	25884501	LAG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401579	25884501	LAG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401579	25884501	LAG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401579	25884501	LAG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4446470	26075268	Guangying Qi	2	contributed equally to this work	contributed equally to this work	-	-	NO
4446470	26075268	Sien Zeng	2	contributed equally to this work	contributed equally to this work	-	-	NO
2909146	20598119	AC	PLoS52	conceived the study|established the flow cytometry based assays|participated to the collection of patient samples|analyzed data|wrote the paper	conceived the study	Conceived and designed the experiments	Conceptualization	YES
2909146	20598119	AC	PLoS52	conceived the study|established the flow cytometry based assays|participated to the collection of patient samples|analyzed data|wrote the paper	established the flow cytometry based assays	Performed the experiments	Investigation	YES
2909146	20598119	AC	PLoS52	conceived the study|established the flow cytometry based assays|participated to the collection of patient samples|analyzed data|wrote the paper	participated to the collection of patient samples	Performed the experiments	Investigation	YES
2909146	20598119	AC	PLoS52	conceived the study|established the flow cytometry based assays|participated to the collection of patient samples|analyzed data|wrote the paper	analyzed data	Analyzed the data	Formal analysis	YES
2909146	20598119	AC	PLoS52	conceived the study|established the flow cytometry based assays|participated to the collection of patient samples|analyzed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
2909146	20598119	CJD	PLoS52	established the flow cytometry based assays|performed experiments|analyzed data	established the flow cytometry based assays	Performed the experiments	Investigation	YES
2909146	20598119	CJD	PLoS52	established the flow cytometry based assays|performed experiments|analyzed data	performed experiments	Performed the experiments	Investigation	YES
2909146	20598119	CJD	PLoS52	established the flow cytometry based assays|performed experiments|analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
2909146	20598119	DH	PLoS52	performed experiments	performed experiments	Performed the experiments	Investigation	YES
2909146	20598119	ES	PLoS52	participated to the collection of patient samples	participated to the collection of patient samples	Performed the experiments	Investigation	YES
2909146	20598119	EV	PLoS52	participated to the collection of patient samples	participated to the collection of patient samples	Performed the experiments	Investigation	YES
2909146	20598119	FDG	PLoS52	participated to the collection of patient samples	participated to the collection of patient samples	Performed the experiments	Investigation	YES
2909146	20598119	GP	PLoS52	conceived the study|participated to the collection of patient samples	conceived the study	Conceived and designed the experiments	Conceptualization	YES
2909146	20598119	GP	PLoS52	conceived the study|participated to the collection of patient samples	participated to the collection of patient samples	Performed the experiments	Investigation	YES
2909146	20598119	GT	PLoS52	participated to the collection of patient samples	participated to the collection of patient samples	Performed the experiments	Investigation	YES
2909146	20598119	HJS	PLoS52	participated to the collection of patient samples	participated to the collection of patient samples	Performed the experiments	Investigation	YES
2909146	20598119	JRB	PLoS52	participated to the collection of patient samples	participated to the collection of patient samples	Performed the experiments	Investigation	YES
2909146	20598119	MM	PLoS52	conceived the study|analyzed data	conceived the study	Conceived and designed the experiments	Conceptualization	YES
2909146	20598119	MM	PLoS52	conceived the study|analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
2909146	20598119	MT	PLoS52	participated to the collection of patient samples	participated to the collection of patient samples	Performed the experiments	Investigation	YES
2909146	20598119	PB	PLoS52	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
2909146	20598119	PL	PLoS52	contributed to research and critical discussion	contributed to research and critical discussion	-	-	NO
2909146	20598119	PR	PLoS52	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
2909146	20598119	RD	PLoS52	participated to the collection of patient samples	participated to the collection of patient samples	Performed the experiments	Investigation	YES
2909146	20598119	SA	PLoS52	established the flow cytometry based assays|performed experiments|analyzed data	established the flow cytometry based assays	Performed the experiments	Investigation	YES
2909146	20598119	SA	PLoS52	established the flow cytometry based assays|performed experiments|analyzed data	performed experiments	Performed the experiments	Investigation	YES
2909146	20598119	SA	PLoS52	established the flow cytometry based assays|performed experiments|analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
2909146	20598119	SG	PLoS52	participated to the collection of patient samples	participated to the collection of patient samples	Performed the experiments	Investigation	YES
2909146	20598119	SH	PLoS52	performed experiments|analyzed data	performed experiments	Performed the experiments	Investigation	YES
2909146	20598119	SH	PLoS52	performed experiments|analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
2909146	20598119	SK	PLoS52	established the flow cytometry based assays|performed experiments|analyzed data	established the flow cytometry based assays	Performed the experiments	Investigation	YES
2909146	20598119	SK	PLoS52	established the flow cytometry based assays|performed experiments|analyzed data	performed experiments	Performed the experiments	Investigation	YES
2909146	20598119	SK	PLoS52	established the flow cytometry based assays|performed experiments|analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
2909146	20598119	TV	PLoS52	participated to the collection of patient samples	participated to the collection of patient samples	Performed the experiments	Investigation	YES
2909146	20598119	UP	PLoS52	contributed to research and critical discussion	contributed to research and critical discussion	-	-	NO
2909146	20598119	VE	PLoS52	conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
2647535	19099568	AW	2	has contributed to the conception and design of the study, interpretation of data, drafting and revising the manuscript and has given final approval of the version to be published	has contributed to the conception and design of the study, interpretation of data, drafting and revising the manuscript and has given final approval of the version to be published	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
2647535	19099568	KD	2	has contributed to the data acquisition and has given final approval of the version to be published	has contributed to the data acquisition and has given final approval of the version to be published	Performed the experiments	Investigation	YES
2647535	19099568	LN	2	has contributed to the interpretation of data, drafting and revising the manuscript and has given final approval of the version to be published	has contributed to the interpretation of data, drafting and revising the manuscript and has given final approval of the version to be published	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft|Writing - Review & Editing	YES
2647535	19099568	PJ	2	has contributed to the conception and design of the study, analysis and interpretation, drafting and revising the manuscript and has given final approval of the version to be published	has contributed to the conception and design of the study, analysis and interpretation, drafting and revising the manuscript and has given final approval of the version to be published	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5477562	28676811	AJ	2	identified and defined the lineages by molecular genotyping	identified and defined the lineages by molecular genotyping	Performed the experiments	Investigation	YES
5477562	28676811	All authors	2	read and contributed to the revision of the manuscript	read and contributed to the revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5477562	28676811	CS	2	assisted in recovery and multiplication of isolates and performed the race phenotyping	assisted in recovery and multiplication of isolates and performed the race phenotyping	Performed the experiments	Investigation	YES
5477562	28676811	DH	2	contributed to collection of isolates|compiled and uploaded data into the database	contributed to collection of isolates	Performed the experiments	Investigation	YES
5477562	28676811	DH	2	contributed to collection of isolates|compiled and uploaded data into the database	compiled and uploaded data into the database	Contributed reagents/materials/analysis tools	Data curation|Software	YES
5477562	28676811	JH	2	compiled and uploaded data into the database|analyzed the data and designed the research	compiled and uploaded data into the database	Contributed reagents/materials/analysis tools	Data curation|Software	YES
5477562	28676811	JH	2	compiled and uploaded data into the database|analyzed the data and designed the research	analyzed the data and designed the research	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5477562	28676811	JR	2	assisted in recovery and multiplication of isolates and performed the race phenotyping|interpreted and quality controlled the race phenotype data|compiled and uploaded data into the database	assisted in recovery and multiplication of isolates and performed the race phenotyping	Performed the experiments	Investigation	YES
5477562	28676811	JR	2	assisted in recovery and multiplication of isolates and performed the race phenotyping|interpreted and quality controlled the race phenotype data|compiled and uploaded data into the database	interpreted and quality controlled the race phenotype data	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Validation	YES
5477562	28676811	JR	2	assisted in recovery and multiplication of isolates and performed the race phenotyping|interpreted and quality controlled the race phenotype data|compiled and uploaded data into the database	compiled and uploaded data into the database	Contributed reagents/materials/analysis tools	Data curation|Software	YES
5477562	28676811	KN	2	contributed to collection of isolates	contributed to collection of isolates	Performed the experiments	Investigation	YES
5477562	28676811	MH	2	contributed to collection of isolates|assisted in recovery and multiplication of isolates and performed the race phenotyping|interpreted and quality controlled the race phenotype data|compiled and uploaded data into the database|analyzed the data and designed the research|identified and defined the lineages by molecular genotyping|wrote the manuscript	contributed to collection of isolates	Performed the experiments	Investigation	YES
5477562	28676811	MH	2	contributed to collection of isolates|assisted in recovery and multiplication of isolates and performed the race phenotyping|interpreted and quality controlled the race phenotype data|compiled and uploaded data into the database|analyzed the data and designed the research|identified and defined the lineages by molecular genotyping|wrote the manuscript	assisted in recovery and multiplication of isolates and performed the race phenotyping	Performed the experiments	Investigation	YES
5477562	28676811	MH	2	contributed to collection of isolates|assisted in recovery and multiplication of isolates and performed the race phenotyping|interpreted and quality controlled the race phenotype data|compiled and uploaded data into the database|analyzed the data and designed the research|identified and defined the lineages by molecular genotyping|wrote the manuscript	interpreted and quality controlled the race phenotype data	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Validation	YES
5477562	28676811	MH	2	contributed to collection of isolates|assisted in recovery and multiplication of isolates and performed the race phenotyping|interpreted and quality controlled the race phenotype data|compiled and uploaded data into the database|analyzed the data and designed the research|identified and defined the lineages by molecular genotyping|wrote the manuscript	compiled and uploaded data into the database	Contributed reagents/materials/analysis tools	Data curation|Software	YES
5477562	28676811	MH	2	contributed to collection of isolates|assisted in recovery and multiplication of isolates and performed the race phenotyping|interpreted and quality controlled the race phenotype data|compiled and uploaded data into the database|analyzed the data and designed the research|identified and defined the lineages by molecular genotyping|wrote the manuscript	analyzed the data and designed the research	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5477562	28676811	MH	2	contributed to collection of isolates|assisted in recovery and multiplication of isolates and performed the race phenotyping|interpreted and quality controlled the race phenotype data|compiled and uploaded data into the database|analyzed the data and designed the research|identified and defined the lineages by molecular genotyping|wrote the manuscript	identified and defined the lineages by molecular genotyping	Performed the experiments	Investigation	YES
5477562	28676811	MH	2	contributed to collection of isolates|assisted in recovery and multiplication of isolates and performed the race phenotyping|interpreted and quality controlled the race phenotype data|compiled and uploaded data into the database|analyzed the data and designed the research|identified and defined the lineages by molecular genotyping|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5477562	28676811	PL	2	compiled and uploaded data into the database	compiled and uploaded data into the database	Contributed reagents/materials/analysis tools	Data curation|Software	YES
5477562	28676811	SA	2	contributed to collection of isolates|compiled and uploaded data into the database|analyzed the data and designed the research|identified and defined the lineages by molecular genotyping|wrote the manuscript	contributed to collection of isolates	Performed the experiments	Investigation	YES
5477562	28676811	SA	2	contributed to collection of isolates|compiled and uploaded data into the database|analyzed the data and designed the research|identified and defined the lineages by molecular genotyping|wrote the manuscript	compiled and uploaded data into the database	Contributed reagents/materials/analysis tools	Data curation|Software	YES
5477562	28676811	SA	2	contributed to collection of isolates|compiled and uploaded data into the database|analyzed the data and designed the research|identified and defined the lineages by molecular genotyping|wrote the manuscript	analyzed the data and designed the research	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5477562	28676811	SA	2	contributed to collection of isolates|compiled and uploaded data into the database|analyzed the data and designed the research|identified and defined the lineages by molecular genotyping|wrote the manuscript	identified and defined the lineages by molecular genotyping	Performed the experiments	Investigation	YES
5477562	28676811	SA	2	contributed to collection of isolates|compiled and uploaded data into the database|analyzed the data and designed the research|identified and defined the lineages by molecular genotyping|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5477562	28676811	TT	2	assisted in recovery and multiplication of isolates and performed the race phenotyping|identified and defined the lineages by molecular genotyping	assisted in recovery and multiplication of isolates and performed the race phenotyping	Performed the experiments	Investigation	YES
5477562	28676811	TT	2	assisted in recovery and multiplication of isolates and performed the race phenotyping|identified and defined the lineages by molecular genotyping	identified and defined the lineages by molecular genotyping	Performed the experiments	Investigation	YES
4215701	25361827	AB	2	provided significant input in the design of the study, suggested additional analyses, and edited the manuscript	provided significant input in the design of the study, suggested additional analyses, and edited the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
4215701	25361827	IS	2	provided significant input in the design of the study, suggested additional analyses, and edited the manuscript	provided significant input in the design of the study, suggested additional analyses, and edited the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
4215701	25361827	KS	2	designed and conducted the analysis and drafted the manuscript	designed and conducted the analysis and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4215701	25361827	LL	2	provided significant input in the design of the study, suggested additional analyses, and edited the manuscript	provided significant input in the design of the study, suggested additional analyses, and edited the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
4215701	25361827	MM	2	provided significant input in the design of the study, suggested additional analyses, and edited the manuscript	provided significant input in the design of the study, suggested additional analyses, and edited the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
4215701	25361827	MPF	2	designed the study and drafted the manuscript	designed the study and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4215701	25361827	RB	2	provided significant input in the design of the study, suggested additional analyses, and edited the manuscript	provided significant input in the design of the study, suggested additional analyses, and edited the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
5111229	27846817	HSS	2	designed and supervised the next generation sequence experiments	designed and supervised the next generation sequence experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Supervision	YES
5111229	27846817	ICH	2	carried out the clock gene functional studies, participated in the data analysis and drafted the manuscript	carried out the clock gene functional studies, participated in the data analysis and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5111229	27846817	SJL	2	designed, analyzed, supervised all experiments, and revised the manuscript	designed, analyzed, supervised all experiments, and revised the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Supervision|Writing - Review & Editing	YES
5111229	27846817	TMC	2	designed, analyzed and supervised mirnaome and transcriptome experiments, and edited the manuscript	designed, analyzed and supervised mirnaome and transcriptome experiments, and edited the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Supervision|Writing - Review & Editing	YES
5111229	27846817	YCH	2	carried out cold shock scheme analysis, mirnaome and transcriptome analysis and drafted the manuscript	carried out cold shock scheme analysis, mirnaome and transcriptome analysis and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4401616	25884854	AA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Revised the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401616	25884854	AA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Revised the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4401616	25884854	AA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Revised the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4401616	25884854	AA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Revised the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401616	25884854	AA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Revised the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401616	25884854	AA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Revised the manuscript	Revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4401616	25884854	CSW	PLoS5	Contributed reagents/materials/analysis tools|Supervised the work	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401616	25884854	CSW	PLoS5	Contributed reagents/materials/analysis tools|Supervised the work	Supervised the work	-	Supervision	YES
4401616	25884854	RWI	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401616	25884854	SI	PLoS5	Contributed reagents/materials/analysis tools|Revised the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401616	25884854	SI	PLoS5	Contributed reagents/materials/analysis tools|Revised the manuscript	Revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
2913913	20618951	BES-B	2	also guided writing of the manuscript	also guided writing of the manuscript	Wrote the paper	Supervision|Writing - Original Draft	YES
2913913	20618951	BS	2	prepared the test articles and performed the attachment, fusion, cervico-vaginal cell line, and lactobacillus assays	prepared the test articles and performed the attachment, fusion, cervico-vaginal cell line, and lactobacillus assays	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
2913913	20618951	CLS	2	initiated the study, coordinated the technical team, wrote the first manuscript draft, and presented the data at meetings	initiated the study, coordinated the technical team, wrote the first manuscript draft, and presented the data at meetings	Conceived and designed the experiments|Wrote the paper	Conceptualization|Project administration|Writing - Original Draft	YES
2913913	20618951	KM	2	prepared the test articles and performed the attachment, fusion, cervico-vaginal cell line, and lactobacillus assays	prepared the test articles and performed the attachment, fusion, cervico-vaginal cell line, and lactobacillus assays	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
2913913	20618951	LND	2	carried out some of the lactobacillus assays	carried out some of the lactobacillus assays	Performed the experiments	Investigation	YES
2913913	20618951	MCO	2	performed the cell-associated and pbmc assays	performed the cell-associated and pbmc assays	Performed the experiments	Investigation	YES
2913913	20618951	MM	2	performed the cell-associated and pbmc assays	performed the cell-associated and pbmc assays	Performed the experiments	Investigation	YES
2913913	20618951	NRH	2	analyzed the data and generated publication-quality figures	analyzed the data and generated publication-quality figures	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation|Visualization	YES
2662816	19291290	AS	2	examined medical checks of the experiment subjects	examined medical checks of the experiment subjects	-	-	NO
2662816	19291290	KE	2	performed measurement and evaluation of nirs data	performed measurement and evaluation of nirs data	Performed the experiments	Investigation	YES
2662816	19291290	MN	2	performed measurement and evaluation of nirs data	performed measurement and evaluation of nirs data	Performed the experiments	Investigation	YES
2662816	19291290	MO	2	performed selection of the experiment subjects as well as the measurement and evaluation of nirs data	performed selection of the experiment subjects as well as the measurement and evaluation of nirs data	Performed the experiments	Investigation	YES
2662816	19291290	NM	2	performed selection and medical checks of the experiment subjects	performed selection and medical checks of the experiment subjects	Performed the experiments	Investigation	YES
2662816	19291290	TH	2	served as the general administrator for the experiment and performed the cast immobilization process	served as the general administrator for the experiment and performed the cast immobilization process	Performed the experiments	Investigation	YES
2662816	19291290	TK	2	examined medical checks of the experiment subjects	examined medical checks of the experiment subjects	-	-	NO
2662816	19291290	TO	2	performed selection and medical checks of the experiment subjects	performed selection and medical checks of the experiment subjects	Performed the experiments	Investigation	YES
2662816	19291290	YK	2	performed measurement and evaluation of nirs data	performed measurement and evaluation of nirs data	Performed the experiments	Investigation	YES
4220001	25371218	AMH	2	led the data collection, analysis and manuscript preparation|oversaw implementation of the research	led the data collection, analysis and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4220001	25371218	AMH	2	led the data collection, analysis and manuscript preparation|oversaw implementation of the research	oversaw implementation of the research	Performed the experiments	Investigation|Supervision	YES
4220001	25371218	CCP	2	designed the study|obtained the funding	designed the study	Conceived and designed the experiments	Methodology	YES
4220001	25371218	CCP	2	designed the study|obtained the funding	obtained the funding	-	Funding acquisition	YES
4220001	25371218	CGM	2	designed the study|obtained the funding	designed the study	Conceived and designed the experiments	Methodology	YES
4220001	25371218	CGM	2	designed the study|obtained the funding	obtained the funding	-	Funding acquisition	YES
4220001	25371218	CM	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
4220001	25371218	HS	2	contributed to data analysis and writing|designed the study	contributed to data analysis and writing	Analyzed the data|Wrote the paper	Formal analysis	YES
4220001	25371218	HS	2	contributed to data analysis and writing|designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
4220001	25371218	KM	2	contributed to data collection, analysis and manuscript preparation	contributed to data collection, analysis and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4220001	25371218	NW	2	contributed to data collection, analysis and manuscript preparation|designed the study|oversaw implementation of the research	contributed to data collection, analysis and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4220001	25371218	NW	2	contributed to data collection, analysis and manuscript preparation|designed the study|oversaw implementation of the research	designed the study	Conceived and designed the experiments	Methodology	YES
4220001	25371218	NW	2	contributed to data collection, analysis and manuscript preparation|designed the study|oversaw implementation of the research	oversaw implementation of the research	Performed the experiments	Investigation|Supervision	YES
4220001	25371218	SDM	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5477565	28676802	All authors	PLoS52	contributed to the discussion and approved the final manuscript	contributed to the discussion and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5477565	28676802	KF	PLoS52	conceived and designed the experiments|wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5477565	28676802	KF	PLoS52	conceived and designed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5477565	28676802	TA	PLoS52	conceived and designed the experiments|wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5477565	28676802	TA	PLoS52	conceived and designed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5111240	27846808	AJH	2	generated the gene sets for the five new species, designed and performed the bioinformatic analyses and drafted the manuscript	generated the gene sets for the five new species, designed and performed the bioinformatic analyses and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5111240	27846808	GC	2	conceived of the study, and participated in its design and coordination	conceived of the study, and participated in its design and coordination	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
5111240	27846808	LR	2	conceived of the study, and participated in its design and coordination	conceived of the study, and participated in its design and coordination	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
4401624	25884504	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the software	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401624	25884504	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the software	Performed the experiments	Performed the experiments	Investigation	YES
4401624	25884504	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the software	Analyzed the data	Analyzed the data	Formal analysis	YES
4401624	25884504	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the software	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401624	25884504	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the software	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401624	25884504	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the software	Designed the software	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
4401624	25884504	SD	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the software	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401624	25884504	SD	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the software	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401624	25884504	SD	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the software	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401624	25884504	SD	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the software	Designed the software	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
2914641	20630064	GM	2	conceived of the study, participated in study design, data interpretation, and critically revised manuscript	conceived of the study, participated in study design, data interpretation, and critically revised manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Review & Editing	YES
2914641	20630064	HMM	2	participated in study design, data interpretation, and critical revision of the manuscript	participated in study design, data interpretation, and critical revision of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
2914641	20630064	JAD	2	participated in study design, acquisition of data and critically revised the manuscript	participated in study design, acquisition of data and critically revised the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
2914641	20630064	JSvdW	2	participated in study design, population pharmacokinetic analysis and helped to draft and critically revise manuscript	participated in study design, population pharmacokinetic analysis and helped to draft and critically revise manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft|Writing - Review & Editing	YES
2914641	20630064	MB	2	performed statistical analysis and helped to draft and revise manuscript	performed statistical analysis and helped to draft and revise manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
2914641	20630064	NSL	2	participated in study design and acquisition of data	participated in study design and acquisition of data	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
2914641	20630064	PJS	2	performed analysis of the samples and helped to draft the manuscript	performed analysis of the samples and helped to draft the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
2914641	20630064	PZS	2	participated in the study design, acquisition of data, data analysis and interpretation, and drafted the manuscript	participated in the study design, acquisition of data, data analysis and interpretation, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
2684094	19389238	IS	2	conceived the study, participated in study design, and statistical analysis, revised manuscript and gave final approval of the version to be published	conceived the study, participated in study design, and statistical analysis, revised manuscript and gave final approval of the version to be published	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Review & Editing	YES
2684094	19389238	JB	2	conceived the study, participated in study design, data collection, calculation, and statistical analysis, drafted and revised manuscript	conceived the study, participated in study design, data collection, calculation, and statistical analysis, drafted and revised manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
2684094	19389238	RM	2	conceived the study, participated in study design and revised manuscript	conceived the study, participated in study design and revised manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
5478679	28680435	BC	PLoS5	Provided the materials	Provided the materials	Contributed reagents/materials/analysis tools	Resources	YES
5478679	28680435	GC	PLoS5	Provided the materials	Provided the materials	Contributed reagents/materials/analysis tools	Resources	YES
5478679	28680435	HC	PLoS5	Provided the materials	Provided the materials	Contributed reagents/materials/analysis tools	Resources	YES
5478679	28680435	JL	PLoS5	Designed the study|Wrote the paper	Designed the study	Conceived and designed the experiments	Methodology	YES
5478679	28680435	JL	PLoS5	Designed the study|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5478679	28680435	LY	PLoS5	Designed the study|Performed the experiment and analyzed the data|Wrote the paper	Designed the study	Conceived and designed the experiments	Methodology	YES
5478679	28680435	LY	PLoS5	Designed the study|Performed the experiment and analyzed the data|Wrote the paper	Performed the experiment and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5478679	28680435	LY	PLoS5	Designed the study|Performed the experiment and analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5112629	27852226	A. Copeland	2	made the library preps and assembled the genomes	made the library preps and assembled the genomes	-	-	NO
5112629	27852226	B. Sullivan	2	conceived the study|discussed the results	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5112629	27852226	B. Sullivan	2	conceived the study|discussed the results	discussed the results	-	-	NO
5112629	27852226	C. Gregory	2	isolated cyanophages, extracted the dna, and analyzed their genomes	isolated cyanophages, extracted the dna, and analyzed their genomes	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5112629	27852226	C. Ignacio-Espinoza	2	ran the whole genome comparisons with previously published viral-tagged metagenomic sequences	ran the whole genome comparisons with previously published viral-tagged metagenomic sequences	Performed the experiments	Investigation	YES
5112629	27852226	S. Solonenko	2	performed the automatic barcode gap discovery analyses	performed the automatic barcode gap discovery analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5112629	27852226	Z. Worden	2	put together the cruise to obtain the seawater samples and ran the 16s analyses|obtained funding for the project	put together the cruise to obtain the seawater samples and ran the 16s analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5112629	27852226	Z. Worden	2	put together the cruise to obtain the seawater samples and ran the 16s analyses|obtained funding for the project	obtained funding for the project	-	Funding acquisition	YES
4401641	25885810	CW	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401641	25885810	CW	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401641	25885810	CW	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401641	25885810	CW	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401641	25885810	TK	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401641	25885810	TK	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401641	25885810	VI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401641	25885810	VI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401641	25885810	VI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401641	25885810	VI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401641	25885810	VI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2917394	20659345	SJB	2	involved in data analysis and revision of the manuscript	involved in data analysis and revision of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
2917394	20659345	XZ	2	participated in its design and helped to draft the manuscript	participated in its design and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
2917394	20659345	YC	2	carried out the cd spectrometry study	carried out the cd spectrometry study	Performed the experiments	Investigation	YES
2917394	20659345	YJ	2	is the principal investigator in this study	is the principal investigator in this study	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
4221500	25373519	AV	2	contributed to the design of the analysis and writing of the manuscript	contributed to the design of the analysis and writing of the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
4221500	25373519	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4221500	25373519	CA	2	contributed to the conception and writing of the manuscript	contributed to the conception and writing of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4221500	25373519	CW	2	provided overall guidance for the study design, analysis and writing of the manuscript	provided overall guidance for the study design, analysis and writing of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Original Draft	YES
4221500	25373519	JJ	2	contributed to the conception and writing of the manuscript	contributed to the conception and writing of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4221500	25373519	LH	2	contributed to the design of the analysis and writing of the manuscript	contributed to the design of the analysis and writing of the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
4221500	25373519	MR	2	contributed significantly to the design of the systematic search, review of articles, analysis of data and drafting the manuscript	contributed significantly to the design of the systematic search, review of articles, analysis of data and drafting the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft|Writing - Review & Editing	YES
4221500	25373519	MS	2	contributed significantly to designing and conducting the systematic search, reviewing articles and extracting data	contributed significantly to designing and conducting the systematic search, reviewing articles and extracting data	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Resources|Writing - Review & Editing	YES
2780382	19900292	KE	2	performed measurement and evaluation of nirs data	performed measurement and evaluation of nirs data	Performed the experiments	Investigation	YES
2780382	19900292	KS	2	performed selection of the experiment subjects as well as the measurement and evaluation of nirs data	performed selection of the experiment subjects as well as the measurement and evaluation of nirs data	Performed the experiments	Investigation	YES
2780382	19900292	KShiroisi	2	performed measurement and evaluation of nirs data	performed measurement and evaluation of nirs data	Performed the experiments	Investigation	YES
2780382	19900292	MN	2	examined medical checks of the experiment subjects	examined medical checks of the experiment subjects	-	-	NO
2780382	19900292	NM	2	served as the general administrator for the experiment and performed the cast immobilization process	served as the general administrator for the experiment and performed the cast immobilization process	Performed the experiments	Investigation	YES
2780382	19900292	RK	2	performed measurement and evaluation of nirs data	performed measurement and evaluation of nirs data	Performed the experiments	Investigation	YES
2780382	19900292	TK	2	performed selection and medical checks of the experiment subjects|examined medical checks of the experiment subjects	performed selection and medical checks of the experiment subjects	Performed the experiments	Investigation	YES
2780382	19900292	TK	2	performed selection and medical checks of the experiment subjects|examined medical checks of the experiment subjects	examined medical checks of the experiment subjects	-	-	NO
2780382	19900292	TO	2	performed selection and medical checks of the experiment subjects|examined medical checks of the experiment subjects	performed selection and medical checks of the experiment subjects	Performed the experiments	Investigation	YES
2780382	19900292	TO	2	performed selection and medical checks of the experiment subjects|examined medical checks of the experiment subjects	examined medical checks of the experiment subjects	-	-	NO
2918521	20646329	ADC	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
2918521	20646329	AS	2	drafted the manuscript|obtained ethical approval and helped with subject recruitment	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
2918521	20646329	AS	2	drafted the manuscript|obtained ethical approval and helped with subject recruitment	obtained ethical approval and helped with subject recruitment	Performed the experiments	Investigation|Project administration	YES
2918521	20646329	GDS	2	obtained ethical approval and helped with subject recruitment	obtained ethical approval and helped with subject recruitment	Performed the experiments	Investigation|Project administration	YES
2918521	20646329	PBS	2	obtained ethical approval and helped with subject recruitment	obtained ethical approval and helped with subject recruitment	Performed the experiments	Investigation|Project administration	YES
2918521	20646329	UN	2	designed the study, performed all laboratory tests and bioinformatics analysis|drafted the manuscript|obtained ethical approval and helped with subject recruitment	designed the study, performed all laboratory tests and bioinformatics analysis	Conceived and designed the experiments|Performed the experiments	Formal analysis|Investigation|Methodology	YES
2918521	20646329	UN	2	designed the study, performed all laboratory tests and bioinformatics analysis|drafted the manuscript|obtained ethical approval and helped with subject recruitment	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
2918521	20646329	UN	2	designed the study, performed all laboratory tests and bioinformatics analysis|drafted the manuscript|obtained ethical approval and helped with subject recruitment	obtained ethical approval and helped with subject recruitment	Performed the experiments	Investigation|Project administration	YES
2918521	20646329	UR	2	provided scientific guidance	provided scientific guidance	-	Supervision	YES
4401647	25886460	CZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401647	25886460	HY	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401647	25886460	SS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401647	25886460	SS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401647	25886460	SS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401647	25886460	SS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401647	25886460	UND	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401647	25886460	UND	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401647	25886460	UND	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401647	25886460	UND	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401647	25886460	XN	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
2801477	20003509	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
2801477	20003509	KM	2	designed the study, supervised all aspects of the study, and performed all administrative tasks associated with the study, revised manuscript	designed the study, supervised all aspects of the study, and performed all administrative tasks associated with the study, revised manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Project administration|Supervision|Writing - Review & Editing	YES
2801477	20003509	MRS	2	data analysis, assisted with manuscript revision|data analysis, assisted with data interpretation, assisted with manuscript revision	data analysis, assisted with manuscript revision	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
2801477	20003509	MRS	2	data analysis, assisted with manuscript revision|data analysis, assisted with data interpretation, assisted with manuscript revision	data analysis, assisted with data interpretation, assisted with manuscript revision	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
2801477	20003509	TT	2	recruited subjects, conducted the testing, performed initial data analysis, wrote initial draft of manuscript	recruited subjects, conducted the testing, performed initial data analysis, wrote initial draft of manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5112662	27852220	RK	2	participated in the design of the study, performed the phylogenetic analyses and structural modeling	participated in the design of the study, performed the phylogenetic analyses and structural modeling	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5112662	27852220	WZ	2	conceived of the study, and participated in its design, carried out database searches and sequence alignments and drafted the manuscript	conceived of the study, and participated in its design, carried out database searches and sequence alignments and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Investigation|Methodology|Software|Writing - Original Draft	YES
5478681	28680437	All authors	5	contributed to manuscript writing and elaboration of figures and Tables	contributed to manuscript writing and elaboration of figures and Tables	Wrote the paper	Visualization|Writing - Original Draft	YES
2920229	20667109	CC	2	designed the experiments and wrote the manuscript	designed the experiments and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
2920229	20667109	LH	2	performed all the experiments	performed all the experiments	Performed the experiments	Investigation	YES
4223282	25377588	All authors	2	have commented on and offered edits to the original draft, and all have read and approved the final version	have commented on and offered edits to the original draft, and all have read and approved the final version	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4223282	25377588	CW	2	are principal investigators on the study, responsible for the overall conceptualisation, design and management of the study	are principal investigators on the study, responsible for the overall conceptualisation, design and management of the study	Conceived and designed the experiments	Conceptualization|Funding acquisition|Methodology|Project administration	YES
4223282	25377588	JN	2	had major input to the development and implementation of monitoring and evaluation instruments, the development of the follow-up questionnaire, and interviewer training, as well as being involved in baseline data collection and data management and implementation and supervision of the follow-up survey	had major input to the development and implementation of monitoring and evaluation instruments, the development of the follow-up questionnaire, and interviewer training, as well as being involved in baseline data collection and data management and implementation and supervision of the follow-up survey	Performed the experiments|Analyzed the data	Data curation|Investigation|Supervision	YES
4223282	25377588	KD	2	are social epidemiologists responsible for major aspects of study design, sampling, development of research instruments, interviewer training and supervision of the quantitative survey	are social epidemiologists responsible for major aspects of study design, sampling, development of research instruments, interviewer training and supervision of the quantitative survey	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Supervision	YES
4223282	25377588	LH	2	supported several aspects of the research particularly the interpretation of the qualitative findings	supported several aspects of the research particularly the interpretation of the qualitative findings	Analyzed the data	Formal analysis	YES
4223282	25377588	LM	2	are principal investigators on the study, responsible for the overall conceptualisation, design and management of the study	are principal investigators on the study, responsible for the overall conceptualisation, design and management of the study	Conceived and designed the experiments	Conceptualization|Funding acquisition|Methodology|Project administration	YES
4223282	25377588	TA	2	are social epidemiologists responsible for major aspects of study design, sampling, development of research instruments, interviewer training and supervision of the quantitative survey	are social epidemiologists responsible for major aspects of study design, sampling, development of research instruments, interviewer training and supervision of the quantitative survey	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Supervision	YES
4223282	25377588	TM	2	are principal investigators on the study, responsible for the overall conceptualisation, design and management of the study	are principal investigators on the study, responsible for the overall conceptualisation, design and management of the study	Conceived and designed the experiments	Conceptualization|Funding acquisition|Methodology|Project administration	YES
2807421	20034396	CMK	2	critically reviewed the manuscript	critically reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
2807421	20034396	CML	2	critically reviewed the manuscript	critically reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
2807421	20034396	MDR	2	contributed in writing the review and aided in the development of the tables	contributed in writing the review and aided in the development of the tables	Wrote the paper	Writing - Review & Editing	YES
2807421	20034396	PST	2	critically reviewed the manuscript	critically reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
2807421	20034396	RBK	2	critically reviewed the manuscript	critically reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
2807421	20034396	VJD	2	developed the concept and wrote the review paper	developed the concept and wrote the review paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
4401655	25884708	AT	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4401655	25884708	AT	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401655	25884708	HS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401655	25884708	HS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401655	25884708	HS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401655	25884708	HS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401655	25884708	HS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401655	25884708	HT	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4401655	25884708	HT	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5112684	27852242	FLL	2	tried the pilot build of the website	tried the pilot build of the website	Contributed reagents/materials/analysis tools	Software	YES
5112684	27852242	FT	2	helped the rna seq and clip-seq analysis, as well as all the lncpro related analysis	helped the rna seq and clip-seq analysis, as well as all the lncpro related analysis	Performed the experiments	Investigation	YES
5112684	27852242	FYS	2	helped arrange the meta data of clip-seq samples	helped arrange the meta data of clip-seq samples	-	Data curation	YES
5112684	27852242	GG	2	conceived and supervised this work|wrote the manuscript	conceived and supervised this work	Conceived and designed the experiments	Conceptualization|Supervision	YES
5112684	27852242	GG	2	conceived and supervised this work|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5112684	27852242	MH	2	designed the architecture and wrote the core code of most analysis modules|designed the annolnc website and wrote all the code of it|wrote the manuscript	designed the architecture and wrote the core code of most analysis modules	Conceived and designed the experiments|Wrote the paper	Software|Writing - Original Draft	YES
5112684	27852242	MH	2	designed the architecture and wrote the core code of most analysis modules|designed the annolnc website and wrote all the code of it|wrote the manuscript	designed the annolnc website and wrote all the code of it	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Software|Writing - Original Draft	YES
5112684	27852242	MH	2	designed the architecture and wrote the core code of most analysis modules|designed the annolnc website and wrote all the code of it|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5112684	27852242	XT	2	designed the architecture and wrote the core code of most analysis modules	designed the architecture and wrote the core code of most analysis modules	Conceived and designed the experiments|Wrote the paper	Software|Writing - Original Draft	YES
2920230	20682034	A. Wanchu	2	helped with clinical characterization of the infected samples	helped with clinical characterization of the infected samples	Performed the experiments	Investigation	YES
2920230	20682034	ACB	2	is the principal investigator responsible for designing the work and writing the manuscript	is the principal investigator responsible for designing the work and writing the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Funding acquisition|Writing - Original Draft	YES
2920230	20682034	S. Singh	2	helped with clinical characterization of the infected samples	helped with clinical characterization of the infected samples	Performed the experiments	Investigation	YES
2920230	20682034	SB	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
2920230	20682034	SS	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
2920230	20682034	UN	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
2920230	20682034	VS	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
2920230	20682034	YS	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5478685	28680434	BR	2	designed experiments and wrote the paper	designed experiments and wrote the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5478685	28680434	LS-M	2	analyzed the data and drafted the paper	analyzed the data and drafted the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5478685	28680434	MM	2	designed and conducted experiments|analyzed the data and drafted the paper	designed and conducted experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5478685	28680434	MM	2	designed and conducted experiments|analyzed the data and drafted the paper	analyzed the data and drafted the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5478685	28680434	ZP	2	designed experiments and wrote the paper	designed experiments and wrote the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
544848	15631633	KH	2	were responsible for conception and design of the study|were responsible for data interpretation, and manuscript preparation	were responsible for conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
544848	15631633	KH	2	were responsible for conception and design of the study|were responsible for data interpretation, and manuscript preparation	were responsible for data interpretation, and manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
544848	15631633	MS	2	were responsible for conception and design of the study|were responsible for data interpretation, and manuscript preparation	were responsible for conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
544848	15631633	MS	2	were responsible for conception and design of the study|were responsible for data interpretation, and manuscript preparation	were responsible for data interpretation, and manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
544848	15631633	PHH	2	were responsible for data interpretation, and manuscript preparation	were responsible for data interpretation, and manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4401659	25885791	HJJ	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401659	25885791	HJJ	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401659	25885791	HK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401659	25885791	HK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401659	25885791	HK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401659	25885791	HK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401659	25885791	HT	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401659	25885791	HT	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401659	25885791	MT	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401659	25885791	MT	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4303328	25541747	All of the authors	2	have given approval to the final version of the manuscript	have given approval to the final version of the manuscript	-	-	NO
2922076	20653950	All authors	2	have given final approval of the manuscript	have given final approval of the manuscript	-	-	NO
2922076	20653950	BL	2	contributed to the design and analysis of the data and drafted the manuscript	contributed to the design and analysis of the data and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
2922076	20653950	GC	2	contributed to the interpretation of the data and revising the manuscript	contributed to the interpretation of the data and revising the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
2922076	20653950	RDM	2	contributed to the acquisition and interpretation of the data and manuscript revisions	contributed to the acquisition and interpretation of the data and manuscript revisions	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Review & Editing	YES
2922076	20653950	SJG	2	contributed to the design and interpretation of the data and manuscript revisions	contributed to the design and interpretation of the data and manuscript revisions	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
4317054	25137441	All authors	2	have given approval to the final version of the manuscript	have given approval to the final version of the manuscript	-	-	NO
5112689	27852223	All authors	2	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5112689	27852223	KS	2	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5112689	27852223	L-YG	2	designed the experiments|were involved in writing the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5112689	27852223	L-YG	2	designed the experiments|were involved in writing the manuscript	were involved in writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5112689	27852223	MH	2	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5112689	27852223	X-WW	2	designed the experiments|performed the experiments and analyzed the data|were involved in writing the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5112689	27852223	X-WW	2	designed the experiments|performed the experiments and analyzed the data|were involved in writing the manuscript	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5112689	27852223	X-WW	2	designed the experiments|performed the experiments and analyzed the data|were involved in writing the manuscript	were involved in writing the manuscript	Wrote the paper	Writing - Original Draft	YES
4401664	25885533	CP	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401664	25885533	DB	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4401664	25885533	DB	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401664	25885533	LJS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Funded the project	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401664	25885533	LJS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Funded the project	Performed the experiments	Performed the experiments	Investigation	YES
4401664	25885533	LJS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Funded the project	Analyzed the data	Analyzed the data	Formal analysis	YES
4401664	25885533	LJS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Funded the project	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401664	25885533	LJS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Funded the project	Funded the project	-	Funding acquisition	YES
4401664	25885533	RCW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Funded the project	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401664	25885533	RCW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Funded the project	Analyzed the data	Analyzed the data	Formal analysis	YES
4401664	25885533	RCW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Funded the project	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401664	25885533	RCW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Funded the project	Funded the project	-	Funding acquisition	YES
5478703	28680436	All authors	2	critically revised and approved the manuscript	critically revised and approved the manuscript	Wrote the paper	Writing - Review & Editing	YES
5478703	28680436	CL	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5478703	28680436	JK	2	conceived and designed the study|wrote the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5478703	28680436	JK	2	conceived and designed the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5478703	28680436	LZ	2	conceived and designed the study|carried out all experiments and analyzed data|wrote the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5478703	28680436	LZ	2	conceived and designed the study|carried out all experiments and analyzed data|wrote the manuscript	carried out all experiments and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5478703	28680436	LZ	2	conceived and designed the study|carried out all experiments and analyzed data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5478703	28680436	MI	2	provided materials and methodology	provided materials and methodology	Performed the experiments|Contributed reagents/materials/analysis tools	Methodology|Resources	YES
5478703	28680436	PU	2	conceived and designed the study|wrote the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5478703	28680436	PU	2	conceived and designed the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
2922885	20682061	AMS	2	carried out data reconciliation by chart reviews	carried out data reconciliation by chart reviews	-	-	NO
2922885	20682061	All authors	2	review and approved final version of manuscript	review and approved final version of manuscript	Wrote the paper	Writing - Review & Editing	YES
2922885	20682061	ERC	2	carried out study design, data collection, statistical analysis and draft manuscript	carried out study design, data collection, statistical analysis and draft manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
2922885	20682061	HJ	2	performed data collection and filled case report forms	performed data collection and filled case report forms	Performed the experiments	Investigation	YES
2922885	20682061	JC	2	carried out data reconciliation by chart reviews	carried out data reconciliation by chart reviews	-	-	NO
2922885	20682061	SK	2	performed data collection and filled case report forms	performed data collection and filled case report forms	Performed the experiments	Investigation	YES
2922885	20682061	WCM	2	participated in every single step of study from conception, design, statistical analysis and drafting of manuscript	participated in every single step of study from conception, design, statistical analysis and drafting of manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
2924251	20687947	AL	2	conceived of the study, and participated in its design and implementation	conceived of the study, and participated in its design and implementation	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
2924251	20687947	All authors	2	contributed to and approved the final manuscript	contributed to and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
2924251	20687947	EA	2	performed the statistical analyses	performed the statistical analyses	Analyzed the data	Formal analysis	YES
2924251	20687947	LF	2	conceived of the study, and participated in its design and implementation	conceived of the study, and participated in its design and implementation	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
2924251	20687947	RBP	2	conceived of the study, and participated in its design and implementation	conceived of the study, and participated in its design and implementation	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
2924251	20687947	RJB	2	performed the statistical analyses	performed the statistical analyses	Analyzed the data	Formal analysis	YES
2924251	20687947	RM	2	conceived of the study, and participated in its design and implementation	conceived of the study, and participated in its design and implementation	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
4401665	25886067	BL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401665	25886067	BL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401665	25886067	GT	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401665	25886067	GT	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401665	25886067	GT	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401665	25886067	HH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401665	25886067	JP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401665	25886067	LM	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401665	25886067	QM	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401665	25886067	XY	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401665	25886067	ZZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401665	25886067	ZZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401665	25886067	ZZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401665	25886067	ZZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4331723	25492398	All authors	2	have given approval to the final version of the manuscript	have given approval to the final version of the manuscript	-	-	NO
5112694	27852217	JRP	PLoS52	designed the research|performed the simulations|analyzed the data	designed the research	Conceived and designed the experiments	Methodology	YES
5112694	27852217	JRP	PLoS52	designed the research|performed the simulations|analyzed the data	performed the simulations	Performed the experiments	Formal analysis|Investigation	YES
5112694	27852217	JRP	PLoS52	designed the research|performed the simulations|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5112694	27852217	LK	PLoS52	designed the research|performed the experiments	designed the research	Conceived and designed the experiments	Methodology	YES
5112694	27852217	LK	PLoS52	designed the research|performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5112694	27852217	PRAK	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5112694	27852217	ST	PLoS52	performed the simulations|analyzed the data	performed the simulations	Performed the experiments	Formal analysis|Investigation	YES
5112694	27852217	ST	PLoS52	performed the simulations|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5112694	27852217	WWM	PLoS52	designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
5112694	27852217	ZLS	PLoS52	designed the research|analyzed the data	designed the research	Conceived and designed the experiments	Methodology	YES
5112694	27852217	ZLS	PLoS52	designed the research|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5478704	28680428	all authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
2933580	20723214	A. Levin	2	designed and performed the experiments, analyzed data and contributed to writing the paper	designed and performed the experiments, analyzed data and contributed to writing the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
2933580	20723214	A. Loyter	2	designed the study, contributed to the writing of the paper and coordinated the study	designed the study, contributed to the writing of the paper and coordinated the study	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft	YES
2933580	20723214	AF	2	designed the study, and contributed to the writing	designed the study, and contributed to the writing	Conceived and designed the experiments|Wrote the paper	Methodology	YES
2933580	20723214	ZH	2	performed peptide synthesis and purification	performed peptide synthesis and purification	Performed the experiments	Investigation	YES
4401666	25885545	DMW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401666	25885545	DMW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401666	25885545	DMW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401666	25885545	FWW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401666	25885545	FWW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401666	25885545	FWW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401666	25885545	RLR	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401666	25885545	RLR	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4317222	25692009	A.V.N.	2	conducted experiments	conducted experiments	Performed the experiments	Investigation	YES
4317222	25692009	G.A.H.	2	participated in research design|performed data analysis|wrote or contributed to writing the manuscript	participated in research design	Conceived and designed the experiments	-	YES
4317222	25692009	G.A.H.	2	participated in research design|performed data analysis|wrote or contributed to writing the manuscript	performed data analysis	Analyzed the data	Formal analysis	YES
4317222	25692009	G.A.H.	2	participated in research design|performed data analysis|wrote or contributed to writing the manuscript	wrote or contributed to writing the manuscript	Wrote the paper	Writing - Original Draft	YES
4317222	25692009	H.D.	2	participated in research design|conducted experiments|performed data analysis|wrote or contributed to writing the manuscript	participated in research design	Conceived and designed the experiments	-	YES
4317222	25692009	H.D.	2	participated in research design|conducted experiments|performed data analysis|wrote or contributed to writing the manuscript	conducted experiments	Performed the experiments	Investigation	YES
4317222	25692009	H.D.	2	participated in research design|conducted experiments|performed data analysis|wrote or contributed to writing the manuscript	performed data analysis	Analyzed the data	Formal analysis	YES
4317222	25692009	H.D.	2	participated in research design|conducted experiments|performed data analysis|wrote or contributed to writing the manuscript	wrote or contributed to writing the manuscript	Wrote the paper	Writing - Original Draft	YES
4317222	25692009	I.A.M.D.	2	performed data analysis	performed data analysis	Analyzed the data	Formal analysis	YES
4317222	25692009	J.D.	2	conducted experiments|conducted experiments|performed data analysis|wrote or contributed to writing the manuscript	conducted experiments	Performed the experiments	Investigation	YES
4317222	25692009	J.D.	2	conducted experiments|conducted experiments|performed data analysis|wrote or contributed to writing the manuscript	conducted experiments	Performed the experiments	Investigation	YES
4317222	25692009	J.D.	2	conducted experiments|conducted experiments|performed data analysis|wrote or contributed to writing the manuscript	performed data analysis	Analyzed the data	Formal analysis	YES
4317222	25692009	J.D.	2	conducted experiments|conducted experiments|performed data analysis|wrote or contributed to writing the manuscript	wrote or contributed to writing the manuscript	Wrote the paper	Writing - Original Draft	YES
4317222	25692009	J.I.	2	conducted experiments	conducted experiments	Performed the experiments	Investigation	YES
4317222	25692009	L.B.S.	2	conducted experiments	conducted experiments	Performed the experiments	Investigation	YES
4317222	25692009	P.J.F.	2	wrote or contributed to writing the manuscript	wrote or contributed to writing the manuscript	Wrote the paper	Writing - Original Draft	YES
4317222	25692009	S.T.	2	performed data analysis	performed data analysis	Analyzed the data	Formal analysis	YES
4317222	25692009	W.L.	2	conducted experiments	conducted experiments	Performed the experiments	Investigation	YES
2933581	20723261	All authors	2	read, assisted in revision and approved the final manuscript	read, assisted in revision and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
2933581	20723261	CN	2	designed primers and optimized pcr for the exon|were involved in analysis of sequencing data	designed primers and optimized pcr for the exon	Conceived and designed the experiments|Performed the experiments	Investigation	YES
2933581	20723261	CN	2	designed primers and optimized pcr for the exon|were involved in analysis of sequencing data	were involved in analysis of sequencing data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
2933581	20723261	EFV	2	in plasma samples	in plasma samples	Performed the experiments	Investigation	YES
2933581	20723261	JG	2	conceived and designed the study helped to draft the manuscript	conceived and designed the study helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
2933581	20723261	TS	2	were both involved in running patients samples	were both involved in running patients samples	-	-	NO
2933581	20723261	VG	2	designed primers and optimized pcr for the exon|collected samples, extracted dna and performed pcr on patient samples|were involved in analysis of sequencing data|were both involved in running patients samples|performed the statistical analysis	designed primers and optimized pcr for the exon	Conceived and designed the experiments|Performed the experiments	Investigation	YES
2933581	20723261	VG	2	designed primers and optimized pcr for the exon|collected samples, extracted dna and performed pcr on patient samples|were involved in analysis of sequencing data|were both involved in running patients samples|performed the statistical analysis	collected samples, extracted dna and performed pcr on patient samples	Performed the experiments	Investigation	YES
2933581	20723261	VG	2	designed primers and optimized pcr for the exon|collected samples, extracted dna and performed pcr on patient samples|were involved in analysis of sequencing data|were both involved in running patients samples|performed the statistical analysis	were involved in analysis of sequencing data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
2933581	20723261	VG	2	designed primers and optimized pcr for the exon|collected samples, extracted dna and performed pcr on patient samples|were involved in analysis of sequencing data|were both involved in running patients samples|performed the statistical analysis	were both involved in running patients samples	-	-	NO
2933581	20723261	VG	2	designed primers and optimized pcr for the exon|collected samples, extracted dna and performed pcr on patient samples|were involved in analysis of sequencing data|were both involved in running patients samples|performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
5478712	28680427	GM	2	conducted the experiment and contributed to writing manuscript	conducted the experiment and contributed to writing manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5478712	28680427	IY	2	conducted economic analysis and contributed to writing manuscript	conducted economic analysis and contributed to writing manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5478712	28680427	JN	2	conceived, designed and conducted the experiment and wrote the manuscript	conceived, designed and conducted the experiment and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Writing - Original Draft	YES
5478712	28680427	PP	2	conceived and designed the experiment, and edited the manuscript	conceived and designed the experiment, and edited the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
5112721	27852222	All authors	2	edited and approved the final manuscript	edited and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5112721	27852222	DA	2	collected and provided the samples for this study	collected and provided the samples for this study	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5112721	27852222	GA	2	conceived the experiments, analyzed the data and drafted the manuscript	conceived the experiments, analyzed the data and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
5112721	27852222	GH	2	conceived the experiments and assisted in data analysis|assisted in drafting the manuscript	conceived the experiments and assisted in data analysis	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
5112721	27852222	GH	2	conceived the experiments and assisted in data analysis|assisted in drafting the manuscript	assisted in drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
5112721	27852222	JE	2	assisted in drafting the manuscript	assisted in drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
5112721	27852222	MG	2	assisted in data analysis and interpretation|assisted in drafting the manuscript	assisted in data analysis and interpretation	Analyzed the data	Formal analysis	YES
5112721	27852222	MG	2	assisted in data analysis and interpretation|assisted in drafting the manuscript	assisted in drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
4401667	25884955	ANS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401667	25884955	DIK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401667	25884955	JMG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401667	25884955	JMG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401667	25884955	JMG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401667	25884955	MHG	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401667	25884955	SYP	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401667	25884955	SYP	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4317228	25692015	Cid Nunez	2	performed data analysis and/or data interpretation|contributed to the discovery of the investigation compound|wrote or contributed to the writing of this manuscript	performed data analysis and/or data interpretation	Analyzed the data	Formal analysis	YES
4317228	25692015	Cid Nunez	2	performed data analysis and/or data interpretation|contributed to the discovery of the investigation compound|wrote or contributed to the writing of this manuscript	contributed to the discovery of the investigation compound	Performed the experiments	Investigation	YES
4317228	25692015	Cid Nunez	2	performed data analysis and/or data interpretation|contributed to the discovery of the investigation compound|wrote or contributed to the writing of this manuscript	wrote or contributed to the writing of this manuscript	Wrote the paper	Writing - Original Draft	YES
4317228	25692015	Le Poul	2	participated in study design	participated in study design	Conceived and designed the experiments	Methodology	YES
2940780	20796284	JGJ	2	contributed to the design of the study, analysis of the data and to writing the manuscript	contributed to the design of the study, analysis of the data and to writing the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Original Draft	YES
2940780	20796284	KAF	2	contributed to the design of the study, analysis of the data and to writing the manuscript	contributed to the design of the study, analysis of the data and to writing the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Original Draft	YES
2940780	20796284	LCI	2	contributed to the design of the study, analysis of the data and to writing the manuscript	contributed to the design of the study, analysis of the data and to writing the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Original Draft	YES
2940780	20796284	YC	2	contributed to analysis of data and writing of the manuscript	contributed to analysis of data and writing of the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
5698877	28985473	C.E.H.	2	contributed equally to this work	contributed equally to this work	-	-	NO
5698877	28985473	T.L.D.	2	contributed equally to this work	contributed equally to this work	-	-	NO
2940781	20796311	DL	2	performed data analysis	performed data analysis	Analyzed the data	Formal analysis	YES
2940781	20796311	EM	2	participated in manuscript writing and preparation	participated in manuscript writing and preparation	Wrote the paper	Writing - Original Draft	YES
2940781	20796311	FN	2	assisted in writing early drafts	assisted in writing early drafts	Wrote the paper	Writing - Original Draft	YES
2940781	20796311	JL	2	provided technical expertise and reviewed and revised manuscript	provided technical expertise and reviewed and revised manuscript	Wrote the paper	Writing - Review & Editing	YES
2940781	20796311	KA	2	obtained funding, designed and implemented the study, participated in data analysis, and wrote the manuscript	obtained funding, designed and implemented the study, participated in data analysis, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Funding acquisition|Investigation|Methodology|Writing - Original Draft	YES
2940781	20796311	MHC	2	helped with study implementation and reviewed and commented on manuscript	helped with study implementation and reviewed and commented on manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
2940781	20796311	VB	2	performed laboratory analyses, and reviewed and commented on manuscript	performed laboratory analyses, and reviewed and commented on manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
5478719	28680429	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5478719	28680429	DJ	2	performed the experiments and analyzed the data|lead rna seq analyses	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5478719	28680429	DJ	2	performed the experiments and analyzed the data|lead rna seq analyses	lead rna seq analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5478719	28680429	DL	2	performed the experiments and analyzed the data|led the orthomcl and snp polymorphism analyses	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5478719	28680429	DL	2	performed the experiments and analyzed the data|led the orthomcl and snp polymorphism analyses	led the orthomcl and snp polymorphism analyses	Analyzed the data	Formal analysis	YES
5478719	28680429	MT	2	contributed to the original concept	contributed to the original concept	Conceived and designed the experiments	Conceptualization	YES
5478719	28680429	RR	2	led the cnv analyses	led the cnv analyses	Analyzed the data	Formal analysis	YES
5478719	28680429	SS	2	performed the experiments and analyzed the data|led the physiological characterization of plants and drafted the manuscript	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5478719	28680429	SS	2	performed the experiments and analyzed the data|led the physiological characterization of plants and drafted the manuscript	led the physiological characterization of plants and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4401669	25885767	HB	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401669	25885767	JZQ	PLoS5	Contributed reagents/materials/analysis tools|Collected materials	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401669	25885767	JZQ	PLoS5	Contributed reagents/materials/analysis tools|Collected materials	Collected materials	Performed the experiments	Investigation	YES
4401669	25885767	LD	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401669	25885767	LL	PLoS5	Contributed reagents/materials/analysis tools|Collected materials	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401669	25885767	LL	PLoS5	Contributed reagents/materials/analysis tools|Collected materials	Collected materials	Performed the experiments	Investigation	YES
4401669	25885767	NW	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401669	25885767	NW	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401669	25885767	NW	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401669	25885767	ZPD	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401669	25885767	ZYL	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401669	25885767	ZYL	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401669	25885767	ZYL	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5112726	27852215	CZL	2	critically revised and modified the draft manuscript	critically revised and modified the draft manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5112726	27852215	GHN	2	critically revised and modified the draft manuscript	critically revised and modified the draft manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5112726	27852215	JZC	2	determined the oil content and fatty acids composition|carried out the cdna samples isolation and performed the sequence analysis	determined the oil content and fatty acids composition	-	-	NO
5112726	27852215	JZC	2	determined the oil content and fatty acids composition|carried out the cdna samples isolation and performed the sequence analysis	carried out the cdna samples isolation and performed the sequence analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5112726	27852215	LJJ	2	conceived and designed the research|contributed to the bioinformatics analysis	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5112726	27852215	LJJ	2	conceived and designed the research|contributed to the bioinformatics analysis	contributed to the bioinformatics analysis	-	Formal analysis	YES
5112726	27852215	PWL	2	determined the oil content and fatty acids composition|carried out the cdna samples isolation and performed the sequence analysis	determined the oil content and fatty acids composition	-	-	NO
5112726	27852215	PWL	2	determined the oil content and fatty acids composition|carried out the cdna samples isolation and performed the sequence analysis	carried out the cdna samples isolation and performed the sequence analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5112726	27852215	QL	2	conceived and designed the research|determined the oil content and fatty acids composition|carried out the cdna samples isolation and performed the sequence analysis|contributed to the bioinformatics analysis|drafted the manuscript and created all the bioinformatics scripts	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5112726	27852215	QL	2	conceived and designed the research|determined the oil content and fatty acids composition|carried out the cdna samples isolation and performed the sequence analysis|contributed to the bioinformatics analysis|drafted the manuscript and created all the bioinformatics scripts	determined the oil content and fatty acids composition	-	-	NO
5112726	27852215	QL	2	conceived and designed the research|determined the oil content and fatty acids composition|carried out the cdna samples isolation and performed the sequence analysis|contributed to the bioinformatics analysis|drafted the manuscript and created all the bioinformatics scripts	carried out the cdna samples isolation and performed the sequence analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5112726	27852215	QL	2	conceived and designed the research|determined the oil content and fatty acids composition|carried out the cdna samples isolation and performed the sequence analysis|contributed to the bioinformatics analysis|drafted the manuscript and created all the bioinformatics scripts	contributed to the bioinformatics analysis	-	Formal analysis	YES
5112726	27852215	QL	2	conceived and designed the research|determined the oil content and fatty acids composition|carried out the cdna samples isolation and performed the sequence analysis|contributed to the bioinformatics analysis|drafted the manuscript and created all the bioinformatics scripts	drafted the manuscript and created all the bioinformatics scripts	Wrote the paper	Formal analysis|Writing - Original Draft	YES
5112726	27852215	YPS	2	drafted the manuscript and created all the bioinformatics scripts|critically revised and modified the draft manuscript	drafted the manuscript and created all the bioinformatics scripts	Wrote the paper	Formal analysis|Writing - Original Draft	YES
5112726	27852215	YPS	2	drafted the manuscript and created all the bioinformatics scripts|critically revised and modified the draft manuscript	critically revised and modified the draft manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6268524	23085658	D.H.	2	contributed to the writing of the manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
6268524	23085658	W.X.	2	planned and designed the experiment|contributed to the writing of the manuscript	planned and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
6268524	23085658	W.X.	2	planned and designed the experiment|contributed to the writing of the manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
4449875	26075227	Ana Paula Grillo	PLoS52	contributed reagents, materials, and analysis tools	contributed reagents, materials, and analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4449875	26075227	Camila Andrea	PLoS52	conceived and designed the experiments|analyzed the data|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4449875	26075227	Camila Andrea	PLoS52	conceived and designed the experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
4449875	26075227	Camila Andrea	PLoS52	conceived and designed the experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4449875	26075227	Edi Lucia Sartorato	PLoS52	contributed reagents, materials, and analysis tools	contributed reagents, materials, and analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4449875	26075227	Flavia Marcorin	PLoS52	contributed reagents, materials, and analysis tools	contributed reagents, materials, and analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4449875	26075227	Gabriela Queila	PLoS52	contributed reagents, materials, and analysis tools	contributed reagents, materials, and analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2942790	20825677	CK	2	participated to the project design and to the coordination and helped drafting the manuscript	participated to the project design and to the coordination and helped drafting the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft	YES
2942790	20825677	EL	2	realized the software applications and participated into the project design	realized the software applications and participated into the project design	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Methodology|Software	YES
2942790	20825677	IdW	2	realized the software applications and participated into the project design	realized the software applications and participated into the project design	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Methodology|Software	YES
2942790	20825677	JE	2	participated to the project design and to the stakeholders involvement	participated to the project design and to the stakeholders involvement	Conceived and designed the experiments	Methodology	YES
2942790	20825677	LF	2	realized the software applications and participated into the project design	realized the software applications and participated into the project design	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Methodology|Software	YES
2942790	20825677	LL	2	conceived the principal idea and looked for funding opportunities	conceived the principal idea and looked for funding opportunities	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
2942790	20825677	MZ	2	wrote the grant proposal, contributed to the educational content development, wrote reports and drafted the manuscript	wrote the grant proposal, contributed to the educational content development, wrote reports and drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
2942790	20825677	VS	2	performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
2942790	20825677	WCL	2	realized the software applications and participated into the project design	realized the software applications and participated into the project design	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Methodology|Software	YES
5478720	28680439	AP	2	evaluated the data and drafted the skeleton of manuscript|revised and finalized the manuscript	evaluated the data and drafted the skeleton of manuscript	Wrote the paper	Writing - Original Draft	YES
5478720	28680439	AP	2	evaluated the data and drafted the skeleton of manuscript|revised and finalized the manuscript	revised and finalized the manuscript	Wrote the paper	Writing - Review & Editing	YES
5478720	28680439	AR	2	conceptualized the topic and designed the experiments|evaluated the data and drafted the skeleton of manuscript|revised and finalized the manuscript	conceptualized the topic and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5478720	28680439	AR	2	conceptualized the topic and designed the experiments|evaluated the data and drafted the skeleton of manuscript|revised and finalized the manuscript	evaluated the data and drafted the skeleton of manuscript	Wrote the paper	Writing - Original Draft	YES
5478720	28680439	AR	2	conceptualized the topic and designed the experiments|evaluated the data and drafted the skeleton of manuscript|revised and finalized the manuscript	revised and finalized the manuscript	Wrote the paper	Writing - Review & Editing	YES
5478720	28680439	GG	2	performed most of the experiments|revised and finalized the manuscript	performed most of the experiments	Performed the experiments	Investigation	YES
5478720	28680439	GG	2	performed most of the experiments|revised and finalized the manuscript	revised and finalized the manuscript	Wrote the paper	Writing - Review & Editing	YES
5478720	28680439	KA	2	conducted some experiments|revised and finalized the manuscript	conducted some experiments	Performed the experiments	Investigation	YES
5478720	28680439	KA	2	conducted some experiments|revised and finalized the manuscript	revised and finalized the manuscript	Wrote the paper	Writing - Review & Editing	YES
5478720	28680439	KK	2	conceptualized the topic and designed the experiments|evaluated the data and drafted the skeleton of manuscript|revised and finalized the manuscript	conceptualized the topic and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5478720	28680439	KK	2	conceptualized the topic and designed the experiments|evaluated the data and drafted the skeleton of manuscript|revised and finalized the manuscript	evaluated the data and drafted the skeleton of manuscript	Wrote the paper	Writing - Original Draft	YES
5478720	28680439	KK	2	conceptualized the topic and designed the experiments|evaluated the data and drafted the skeleton of manuscript|revised and finalized the manuscript	revised and finalized the manuscript	Wrote the paper	Writing - Review & Editing	YES
5478720	28680439	SA	2	conducted some experiments|revised and finalized the manuscript	conducted some experiments	Performed the experiments	Investigation	YES
5478720	28680439	SA	2	conducted some experiments|revised and finalized the manuscript	revised and finalized the manuscript	Wrote the paper	Writing - Review & Editing	YES
5112738	27852218	AO	2	helped with data analysis	helped with data analysis	Analyzed the data	Formal analysis	YES
5112738	27852218	CG	2	performed the bioinformatics experiments and analyzed the data	performed the bioinformatics experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5112738	27852218	KS	2	performed the animal work	performed the animal work	Performed the experiments	Investigation	YES
5112738	27852218	RR	2	performed the animal work|designed the experiments and provided intellectual input|wrote the manuscript	performed the animal work	Performed the experiments	Investigation	YES
5112738	27852218	RR	2	performed the animal work|designed the experiments and provided intellectual input|wrote the manuscript	designed the experiments and provided intellectual input	Conceived and designed the experiments	Methodology	YES
5112738	27852218	RR	2	performed the animal work|designed the experiments and provided intellectual input|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5112738	27852218	SM	2	helped with data analysis	helped with data analysis	Analyzed the data	Formal analysis	YES
5112738	27852218	SS	2	performed the animal work|designed the experiments and provided intellectual input|wrote the manuscript	performed the animal work	Performed the experiments	Investigation	YES
5112738	27852218	SS	2	performed the animal work|designed the experiments and provided intellectual input|wrote the manuscript	designed the experiments and provided intellectual input	Conceived and designed the experiments	Methodology	YES
5112738	27852218	SS	2	performed the animal work|designed the experiments and provided intellectual input|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
2984380	20950432	All authors	2	critically reviewed and approved the final manuscript	critically reviewed and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
2984380	20950432	BW	2	took care of the statistical analysis	took care of the statistical analysis	Analyzed the data	Formal analysis	YES
2984380	20950432	CW	2	assisted in designing the study and provided substantial intellectual content to the manuscript	assisted in designing the study and provided substantial intellectual content to the manuscript	Conceived and designed the experiments	Methodology	YES
2984380	20950432	EvC	2	performed the analysis	performed the analysis	Performed the experiments	Investigation	YES
2984380	20950432	KS	2	designed the study, performed the analysis and prepared the manuscript	designed the study, performed the analysis and prepared the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
2984380	20950432	KvdB	2	performed the analysis	performed the analysis	Performed the experiments	Investigation	YES
2984380	20950432	LS	2	assisted in designing the study and provided substantial intellectual content to the manuscript	assisted in designing the study and provided substantial intellectual content to the manuscript	Conceived and designed the experiments	Methodology	YES
2984380	20950432	MB	2	assisted in drafting the manuscript	assisted in drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
2984380	20950432	TRdW	2	assisted in designing the study and provided substantial intellectual content to the manuscript	assisted in designing the study and provided substantial intellectual content to the manuscript	Conceived and designed the experiments	Methodology	YES
2984380	20950432	WS	2	assisted in designing the study and provided substantial intellectual content to the manuscript	assisted in designing the study and provided substantial intellectual content to the manuscript	Conceived and designed the experiments	Methodology	YES
4401671	25886648	DFM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401671	25886648	DFM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401671	25886648	DFM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401671	25886648	DFM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401671	25886648	JP	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401671	25886648	JP	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401671	25886648	JP	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401671	25886648	JP	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401671	25886648	SD	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401671	25886648	SD	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401671	25886648	SD	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401671	25886648	SD	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4449876	26075235	Ryuichi Yamasaki	2	contributed equally to this work	contributed equally to this work	-	-	NO
4449876	26075235	Takero Otsuka	2	contributed equally to this work	contributed equally to this work	-	-	NO
4449876	26075235	Tateshi Shimazaki	2	contributed equally to this work	contributed equally to this work	-	-	NO
3385613	22761550	B. Bein	2	for conduct of the study	for conduct of the study	Performed the experiments	Investigation	YES
2988692	21034506	AT	2	conceived and designed the study, performed analysis and interpretation of data and drafted the manuscript	conceived and designed the study, performed analysis and interpretation of data and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
2988692	21034506	All authors	2	approved and read the final manuscript|participated in critical appraisal and revision of the manuscript	approved and read the final manuscript	Wrote the paper	Writing - Review & Editing	YES
2988692	21034506	All authors	2	approved and read the final manuscript|participated in critical appraisal and revision of the manuscript	participated in critical appraisal and revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
2988692	21034506	FA	2	assisted with the design, interpretation of data and the critical review of the manuscript	assisted with the design, interpretation of data and the critical review of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
2988692	21034506	SB	2	assisted with the design, interpretation of data and the critical review of the manuscript	assisted with the design, interpretation of data and the critical review of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
2988692	21034506	TB	2	assisted with the design, interpretation of data and the critical review of the manuscript	assisted with the design, interpretation of data and the critical review of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5478723	28680440	AS	PLoS52	performed the experiments, analyzed the data, and wrote the manuscript	performed the experiments, analyzed the data, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5478723	28680440	JT	PLoS52	conceived and designed the experiments|revised the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5478723	28680440	JT	PLoS52	conceived and designed the experiments|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5478723	28680440	KW	PLoS52	conceived and designed the experiments|performed the experiments, analyzed the data, and wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5478723	28680440	KW	PLoS52	conceived and designed the experiments|performed the experiments, analyzed the data, and wrote the manuscript	performed the experiments, analyzed the data, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5478723	28680440	SK	PLoS52	performed the experiments, analyzed the data, and wrote the manuscript	performed the experiments, analyzed the data, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5478723	28680440	SS	PLoS52	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5478723	28680440	TX	PLoS52	performed the experiments, analyzed the data, and wrote the manuscript	performed the experiments, analyzed the data, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5478723	28680440	WT	PLoS52	conceived and designed the experiments|performed the experiments, analyzed the data, and wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5478723	28680440	WT	PLoS52	conceived and designed the experiments|performed the experiments, analyzed the data, and wrote the manuscript	performed the experiments, analyzed the data, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5112743	27852224	AS	1	Research design|Research|Data analysis|Paper	Research design	Conceived and designed the experiments	-	YES
5112743	27852224	AS	1	Research design|Research|Data analysis|Paper	Research	-	-	NO
5112743	27852224	AS	1	Research design|Research|Data analysis|Paper	Data analysis	Analyzed the data	Formal analysis	YES
5112743	27852224	AS	1	Research design|Research|Data analysis|Paper	Paper	-	-	NO
5112743	27852224	EE	1	Research design|Research|Data analysis|Paper	Research design	Conceived and designed the experiments	-	YES
5112743	27852224	EE	1	Research design|Research|Data analysis|Paper	Research	-	-	NO
5112743	27852224	EE	1	Research design|Research|Data analysis|Paper	Data analysis	Analyzed the data	Formal analysis	YES
5112743	27852224	EE	1	Research design|Research|Data analysis|Paper	Paper	-	-	NO
5112743	27852224	FK	1	Research design|Research|Data analysis|Paper	Research design	Conceived and designed the experiments	-	YES
5112743	27852224	FK	1	Research design|Research|Data analysis|Paper	Research	-	-	NO
5112743	27852224	FK	1	Research design|Research|Data analysis|Paper	Data analysis	Analyzed the data	Formal analysis	YES
5112743	27852224	FK	1	Research design|Research|Data analysis|Paper	Paper	-	-	NO
5112743	27852224	MM	1	Paper	Paper	-	-	NO
4401672	25886360	AS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4401672	25886360	AS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401672	25886360	CM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401672	25886360	CM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401672	25886360	CM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401672	25886360	CM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401672	25886360	DYH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401672	25886360	DYH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401672	25886360	DYH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401672	25886360	EBK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401672	25886360	JA	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401672	25886360	JA	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401672	25886360	MA	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401672	25886360	PWS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401672	25886360	PWS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401672	25886360	PWS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401672	25886360	RDG	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401672	25886360	RDG	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401672	25886360	RDG	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401672	25886360	SCO	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401672	25886360	WL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401672	25886360	WL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401672	25886360	WL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401672	25886360	WL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401672	25886360	WZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
2992027	20929543	AVR	2	assisted with study design and reviewed the manuscript	assisted with study design and reviewed the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
2992027	20929543	CMW	2	performed all the laboratory work, statistical analysis, and prepared the manuscript	performed all the laboratory work, statistical analysis, and prepared the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
2992027	20929543	DMM	2	designed the study and cohort, and aided in preparing the manuscript	designed the study and cohort, and aided in preparing the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
2992027	20929543	MSS	2	aided in preparing the manuscript	aided in preparing the manuscript	Wrote the paper	Writing - Original Draft	YES
2992027	20929543	WSS	2	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5478725	28680426	BS	2	contributed to the design of the experiment|advised the studies and critically revised the manuscript	contributed to the design of the experiment	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5478725	28680426	BS	2	contributed to the design of the experiment|advised the studies and critically revised the manuscript	advised the studies and critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5478725	28680426	GV	2	provided the pipelines for sequencing data analysis and advised data analysis|advised the studies and critically revised the manuscript	provided the pipelines for sequencing data analysis and advised data analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5478725	28680426	GV	2	provided the pipelines for sequencing data analysis and advised data analysis|advised the studies and critically revised the manuscript	advised the studies and critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5478725	28680426	JE	2	designed the experiment, carried out the field work, laboratory experiments, data analysis and wrote the manuscript	designed the experiment, carried out the field work, laboratory experiments, data analysis and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5478725	28680426	JJ	2	advised the studies and critically revised the manuscript	advised the studies and critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5478725	28680426	MR	2	advised the studies and critically revised the manuscript	advised the studies and critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5478725	28680426	MS	2	advised the studies and critically revised the manuscript	advised the studies and critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5478725	28680426	PH	2	contributed to the field work and the laboratory experiments	contributed to the field work and the laboratory experiments	Performed the experiments	Investigation	YES
5478725	28680426	PS	2	contributed to the design of the experiment|advised the studies and critically revised the manuscript	contributed to the design of the experiment	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5478725	28680426	PS	2	contributed to the design of the experiment|advised the studies and critically revised the manuscript	advised the studies and critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4317234	25692021	B.M.S.	2	performed the 5-ct infusion and revised the manuscript	performed the 5-ct infusion and revised the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4317234	25692021	E.S.D.	2	performed western analyses and immunohistochemistry, and revised the manuscript	performed western analyses and immunohistochemistry, and revised the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
4317234	25692021	J.M.T.	2	performed real-time rt pcr, western analyses, and revised the manuscript	performed real-time rt pcr, western analyses, and revised the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
4317234	25692021	S.W.W.	2	performed all isolated tissue bath experiments, drafted and revised the manuscript	performed all isolated tissue bath experiments, drafted and revised the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
4401673	25886196	GG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401673	25886196	KX	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401673	25886196	WF	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401673	25886196	YF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401673	25886196	YF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401673	25886196	YF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401673	25886196	YF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401673	25886196	YL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401673	25886196	YX	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401673	25886196	ZD	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401673	25886196	ZD	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3385616	22778697	Chi-Neu Tsai	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
3385616	22778697	Chun-Tien Chang	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
3001414	21092280	CBA	2	extracted the data, performed the data analysis, and wrote the paper	extracted the data, performed the data analysis, and wrote the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3001414	21092280	MJ	2	collaborated to the statistical analysis	collaborated to the statistical analysis	Analyzed the data	Formal analysis	YES
5114726	27855634	AR	2	participated in the rna seq and ipa analyses, generated tables and figures, and drafted the initial manuscript	participated in the rna seq and ipa analyses, generated tables and figures, and drafted the initial manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Visualization|Writing - Original Draft	YES
5114726	27855634	AS	2	carried out the rna seq analysis, generated figures, performed the statistical and ipa analyses, and participated in drafting the manuscript	carried out the rna seq analysis, generated figures, performed the statistical and ipa analyses, and participated in drafting the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Visualization|Writing - Original Draft	YES
5114726	27855634	JTT	2	conceived and designed the study, analyzed and summarized processed data, and participated in drafting, editing, and revising the manuscript	conceived and designed the study, analyzed and summarized processed data, and participated in drafting, editing, and revising the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Data curation|Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5114726	27855634	YI	2	carried out the rna sequencing and participated in data processing, statistical analysis, and drafting the manuscript	carried out the rna sequencing and participated in data processing, statistical analysis, and drafting the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Formal analysis|Investigation|Writing - Original Draft	YES
5478728	28680430	AS	2	were involved in the design of the research idea and contributed in writing of the manuscript	were involved in the design of the research idea and contributed in writing of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
5478728	28680430	CH	2	conducted the n- glycan analysis	conducted the n- glycan analysis	Performed the experiments	Investigation	YES
5478728	28680430	DB	2	were involved in the design of the research idea and contributed in writing of the manuscript	were involved in the design of the research idea and contributed in writing of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
5478728	28680430	GM	2	supervised the purification procedures	supervised the purification procedures	Performed the experiments	Investigation|Supervision	YES
5478728	28680430	KK	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5478728	28680430	LW	2	helped in the design of plant expression vectors and plant infiltrations	helped in the design of plant expression vectors and plant infiltrations	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5478728	28680430	MF	2	contributed in the lipid analysis	contributed in the lipid analysis	Performed the experiments	Investigation	YES
5478728	28680430	MM	2	contributed in the lipid analysis	contributed in the lipid analysis	Performed the experiments	Investigation	YES
5478728	28680430	NG	2	supervised the purification procedures	supervised the purification procedures	Performed the experiments	Investigation|Supervision	YES
5478728	28680430	RB	2	made the hek293 constructs	made the hek293 constructs	Performed the experiments	Investigation	YES
4401674	25886563	CDB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401674	25886563	CDB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401674	25886563	CDB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401674	25886563	CDB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401674	25886563	DY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401674	25886563	DY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401674	25886563	DY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401674	25886563	DY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401674	25886563	PJL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401674	25886563	PJL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401674	25886563	PJL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3004805	21134247	EB	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
3004805	21134247	EJH	PLoS52	performed the experiments|wrote the manuscript and performed statistical analyses	performed the experiments	Performed the experiments	Investigation	YES
3004805	21134247	EJH	PLoS52	performed the experiments|wrote the manuscript and performed statistical analyses	wrote the manuscript and performed statistical analyses	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3004805	21134247	GP	PLoS52	supervised and reviewed the manuscript	supervised and reviewed the manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
3004805	21134247	MJG	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
3004805	21134247	RMvdS	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
3004805	21134247	WAP	PLoS52	supervised and reviewed the manuscript	supervised and reviewed the manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
5114764	27855649	BJ	2	carried out the molecular studies	carried out the molecular studies	Performed the experiments	Investigation	YES
5114764	27855649	BZ	2	conceived of the study, and participated in its design|acquired of funding and helped to draft the manuscript	conceived of the study, and participated in its design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5114764	27855649	BZ	2	conceived of the study, and participated in its design|acquired of funding and helped to draft the manuscript	acquired of funding and helped to draft the manuscript	Wrote the paper	Funding acquisition|Writing - Original Draft	YES
5114764	27855649	CS	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5114764	27855649	DY	2	conceived of the study, and participated in its design	conceived of the study, and participated in its design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5114764	27855649	JF	2	carried out the molecular studies	carried out the molecular studies	Performed the experiments	Investigation	YES
5114764	27855649	KY	2	performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
5114764	27855649	LQ	2	carried out the molecular studies	carried out the molecular studies	Performed the experiments	Investigation	YES
5114764	27855649	SK	2	took care the plants	took care the plants	Performed the experiments	Investigation	YES
5114764	27855649	YS	2	carried out the molecular studies	carried out the molecular studies	Performed the experiments	Investigation	YES
5114764	27855649	ZF	2	took care the plants	took care the plants	Performed the experiments	Investigation	YES
5478731	28680425	CP	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5478731	28680425	Dingyou Liu	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5478731	28680425	HQ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5478731	28680425	HS	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5478731	28680425	JCW	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5478731	28680425	JW	PLoS52	conceived this study|analyzed data|wrote the manuscript	conceived this study	Conceived and designed the experiments	Conceptualization	YES
5478731	28680425	JW	PLoS52	conceived this study|analyzed data|wrote the manuscript	analyzed data	Analyzed the data	Formal analysis	YES
5478731	28680425	JW	PLoS52	conceived this study|analyzed data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5478731	28680425	JY	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5478731	28680425	LZ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5478731	28680425	MH	PLoS52	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5478731	28680425	Sigui Li	PLoS52	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5478731	28680425	WL	PLoS52	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5478731	28680425	WM	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5478731	28680425	WW	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5478731	28680425	XC	PLoS52	conceived this study|analyzed data|wrote the manuscript	conceived this study	Conceived and designed the experiments	Conceptualization	YES
5478731	28680425	XC	PLoS52	conceived this study|analyzed data|wrote the manuscript	analyzed data	Analyzed the data	Formal analysis	YES
5478731	28680425	XC	PLoS52	conceived this study|analyzed data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5478731	28680425	XZ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
6103485	29947513	All authors	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
6103485	29947513	G.L.-M.	2	performed, analyzed, and interpreted the experiments	performed, analyzed, and interpreted the experiments	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6103485	29947513	S.K.	2	performed, analyzed, and interpreted the experiments	performed, analyzed, and interpreted the experiments	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6103485	29947513	S.R.-R.	2	performed, analyzed, and interpreted the experiments	performed, analyzed, and interpreted the experiments	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3385618	22792043	C. Huang	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
3009693	21118549	D Heider	2	contributed to data analysis and to drafting of the manuscript	contributed to data analysis and to drafting of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3009693	21118549	D Hoffmann	2	has devised research, analyzed data, and revised the manuscript	has devised research, analyzed data, and revised the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Review & Editing	YES
3009693	21118549	JND	2	devised and carried out the research, analyzed data, and drafted the manuscript	devised and carried out the research, analyzed data, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
4401675	25885664	AR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401675	25885664	AR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401675	25885664	AR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401675	25885664	AR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401675	25885664	AR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401675	25885664	CC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401675	25885664	CC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401675	25885664	CC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401675	25885664	CC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401675	25885664	CC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401675	25885664	DD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401675	25885664	DD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401675	25885664	DD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401675	25885664	DD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401675	25885664	DD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401675	25885664	EB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401675	25885664	EB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401675	25885664	EB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401675	25885664	EB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401675	25885664	EB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401675	25885664	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401675	25885664	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401675	25885664	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401675	25885664	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401675	25885664	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401675	25885664	KF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401675	25885664	KF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401675	25885664	KF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401675	25885664	KF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401675	25885664	KF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401675	25885664	LK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401675	25885664	LK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401675	25885664	LK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401675	25885664	LK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401675	25885664	LK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401675	25885664	PN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401675	25885664	PN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401675	25885664	PN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401675	25885664	PN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401675	25885664	PN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5114810	27855648	AB	2	conceived this project|undertook the experimental design, data analyses and prepared the figures|performed the majority of the bioinformatics analyses|drafted the manuscript, and all authors edited and approved the final manuscript	conceived this project	Conceived and designed the experiments	Conceptualization	YES
5114810	27855648	AB	2	conceived this project|undertook the experimental design, data analyses and prepared the figures|performed the majority of the bioinformatics analyses|drafted the manuscript, and all authors edited and approved the final manuscript	undertook the experimental design, data analyses and prepared the figures	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology|Visualization	YES
5114810	27855648	AB	2	conceived this project|undertook the experimental design, data analyses and prepared the figures|performed the majority of the bioinformatics analyses|drafted the manuscript, and all authors edited and approved the final manuscript	performed the majority of the bioinformatics analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5114810	27855648	AB	2	conceived this project|undertook the experimental design, data analyses and prepared the figures|performed the majority of the bioinformatics analyses|drafted the manuscript, and all authors edited and approved the final manuscript	drafted the manuscript, and all authors edited and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5114810	27855648	AF	2	contributed to experimental design, analyses and conceptual development of the work	contributed to experimental design, analyses and conceptual development of the work	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation|Methodology	YES
5114810	27855648	BB	2	contributed to experimental design, analyses and conceptual development of the work	contributed to experimental design, analyses and conceptual development of the work	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation|Methodology	YES
5114810	27855648	CN	2	conceived this project|undertook the experimental design, data analyses and prepared the figures|drafted the manuscript, and all authors edited and approved the final manuscript	conceived this project	Conceived and designed the experiments	Conceptualization	YES
5114810	27855648	CN	2	conceived this project|undertook the experimental design, data analyses and prepared the figures|drafted the manuscript, and all authors edited and approved the final manuscript	undertook the experimental design, data analyses and prepared the figures	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology|Visualization	YES
5114810	27855648	CN	2	conceived this project|undertook the experimental design, data analyses and prepared the figures|drafted the manuscript, and all authors edited and approved the final manuscript	drafted the manuscript, and all authors edited and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5114810	27855648	GK	2	conceived this project|contributed to experimental design, analyses and conceptual development of the work	conceived this project	Conceived and designed the experiments	Conceptualization	YES
5114810	27855648	GK	2	conceived this project|contributed to experimental design, analyses and conceptual development of the work	contributed to experimental design, analyses and conceptual development of the work	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation|Methodology	YES
5114810	27855648	RH	2	contributed to experimental design, analyses and conceptual development of the work	contributed to experimental design, analyses and conceptual development of the work	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation|Methodology	YES
3018377	21156070	AH	2	designed the sequence database, assembled and curated sequences, performed all bioinformatic analysis, and drafted the manuscript	designed the sequence database, assembled and curated sequences, performed all bioinformatic analysis, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Data curation|Formal analysis|Investigation|Software|Writing - Original Draft	YES
3018377	21156070	DG	2	conceived of the study, participated in its design and coordination, and helped to draft the manuscript	conceived of the study, participated in its design and coordination, and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
3018377	21156070	MM	2	assembled and curated sequences and clinical data	assembled and curated sequences and clinical data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
3018377	21156070	NO	2	designed and implemented the database interface	designed and implemented the database interface	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
3385619	22778695	All authors	2	contributed to the study design	contributed to the study design	Conceived and designed the experiments	Methodology	YES
3385619	22778695	Chao-Wen Chen	2	conceived the study|obtained research funding|drafted the article and all authors contributed substantially to its revision	conceived the study	Conceived and designed the experiments	Conceptualization	YES
3385619	22778695	Chao-Wen Chen	2	conceived the study|obtained research funding|drafted the article and all authors contributed substantially to its revision	obtained research funding	-	Funding acquisition	YES
3385619	22778695	Chao-Wen Chen	2	conceived the study|obtained research funding|drafted the article and all authors contributed substantially to its revision	drafted the article and all authors contributed substantially to its revision	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3385619	22778695	Chi-Ming Chu	2	performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
3385619	22778695	Hsing-Lin Lin	2	collected the data and reviewed the literature on the subject|performed the statistical analysis	collected the data and reviewed the literature on the subject	Performed the experiments	Formal analysis|Investigation	YES
3385619	22778695	Hsing-Lin Lin	2	collected the data and reviewed the literature on the subject|performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
3385619	22778695	Ke-Zong Ma	2	collected the data and reviewed the literature on the subject	collected the data and reviewed the literature on the subject	Performed the experiments	Formal analysis|Investigation	YES
3385619	22778695	Liang-Chi Kuo	2	collected the data and reviewed the literature on the subject	collected the data and reviewed the literature on the subject	Performed the experiments	Formal analysis|Investigation	YES
3385619	22778695	Wei-Che Lee	2	collected the data and reviewed the literature on the subject	collected the data and reviewed the literature on the subject	Performed the experiments	Formal analysis|Investigation	YES
3385619	22778695	Yun-Ting Lou	2	conceived the study|collected the data and reviewed the literature on the subject|drafted the article and all authors contributed substantially to its revision	conceived the study	Conceived and designed the experiments	Conceptualization	YES
3385619	22778695	Yun-Ting Lou	2	conceived the study|collected the data and reviewed the literature on the subject|drafted the article and all authors contributed substantially to its revision	collected the data and reviewed the literature on the subject	Performed the experiments	Formal analysis|Investigation	YES
3385619	22778695	Yun-Ting Lou	2	conceived the study|collected the data and reviewed the literature on the subject|drafted the article and all authors contributed substantially to its revision	drafted the article and all authors contributed substantially to its revision	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5478880	28680431	JT	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
5478880	28680431	JT	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5478880	28680431	KH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5478880	28680431	KW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5478880	28680431	KW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5478880	28680431	KW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5478880	28680431	TS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5478880	28680431	WZ	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5478880	28680431	WZ	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5478880	28680431	XD	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5478880	28680431	YL	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
5478880	28680431	YL	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
3020664	20937122	AL	2	participated in the design of the study and draft the manuscript	participated in the design of the study and draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3020664	20937122	AN	2	participated in the design of the study and draft the manuscript	participated in the design of the study and draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3020664	20937122	BS	2	participated in the design of the study and draft the manuscript	participated in the design of the study and draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3020664	20937122	PT	2	participated in the design of the study and draft the manuscript	participated in the design of the study and draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3020664	20937122	SN	2	participated in the design of the study and draft the manuscript	participated in the design of the study and draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3020664	20937122	SS	2	participated in the design of the study and draft the manuscript	participated in the design of the study and draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3020664	20937122	WM	2	participated in the design of the study, statistical analysis and draft the manuscript|participated in the design of the study and draft the manuscript	participated in the design of the study, statistical analysis and draft the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3020664	20937122	WM	2	participated in the design of the study, statistical analysis and draft the manuscript|participated in the design of the study and draft the manuscript	participated in the design of the study and draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3020664	20937122	WP	2	participated in the design of the study and draft the manuscript	participated in the design of the study and draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5116162	27863463	GA	2	implemented most methods, designed the web interface and participated in the writing	implemented most methods, designed the web interface and participated in the writing	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Software	YES
5116162	27863463	PB	2	conceived the main algorithms implemented in the chip-seq tools, coordinated all development efforts and wrote large parts of the manuscript	conceived the main algorithms implemented in the chip-seq tools, coordinated all development efforts and wrote large parts of the manuscript	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Investigation|Project administration|Software|Writing - Original Draft	YES
5116162	27863463	RD	2	created and populated the mga repository and contributed to some software components	created and populated the mga repository and contributed to some software components	Contributed reagents/materials/analysis tools	Software	YES
5116162	27863463	SK	2	carried out a comprehensive comparison with other resources	carried out a comprehensive comparison with other resources	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5116162	27863463	all authors	2	contributed to the online documentation and tutorials posted on the web site	contributed to the online documentation and tutorials posted on the web site	Contributed reagents/materials/analysis tools	Software	YES
4401676	25884711	A. Pal	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401676	25884711	A. Pal	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401676	25884711	A. Pal	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401676	25884711	A. Patel	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4401676	25884711	A. Patel	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401676	25884711	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401676	25884711	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401676	25884711	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401676	25884711	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401676	25884711	SP	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5478881	28680432	HK	1	The conception or design of the work|The acquisition, analysis	The conception or design of the work	Conceived and designed the experiments	Conceptualization	YES
5478881	28680432	HK	1	The conception or design of the work|The acquisition, analysis	The acquisition, analysis	-	-	NO
5478881	28680432	NS	1	The conception or design of the work|The acquisition, analysis|Drafting the work	The conception or design of the work	Conceived and designed the experiments	Conceptualization	YES
5478881	28680432	NS	1	The conception or design of the work|The acquisition, analysis|Drafting the work	The acquisition, analysis	-	-	NO
5478881	28680432	NS	1	The conception or design of the work|The acquisition, analysis|Drafting the work	Drafting the work	Wrote the paper	Writing - Original Draft	YES
5478881	28680432	PP-S	1	The conception or design of the work|The acquisition, analysis|Drafting the work	The conception or design of the work	Conceived and designed the experiments	Conceptualization	YES
5478881	28680432	PP-S	1	The conception or design of the work|The acquisition, analysis|Drafting the work	The acquisition, analysis	-	-	NO
5478881	28680432	PP-S	1	The conception or design of the work|The acquisition, analysis|Drafting the work	Drafting the work	Wrote the paper	Writing - Original Draft	YES
5478881	28680432	PS	1	The acquisition, analysis|Drafting the work	The acquisition, analysis	-	-	NO
5478881	28680432	PS	1	The acquisition, analysis|Drafting the work	Drafting the work	Wrote the paper	Writing - Original Draft	YES
3022662	21156072	AT	2	participated in the study concept and design, carried out acquisition of the data, submitted critical revisions of the manuscript for important intellectual content, and provided administrative, technical or material support for the study	participated in the study concept and design, carried out acquisition of the data, submitted critical revisions of the manuscript for important intellectual content, and provided administrative, technical or material support for the study	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Investigation|Methodology|Project administration|Resources|Writing - Review & Editing	YES
3022662	21156072	BM	2	participated in the study concept and design, carried out acquisition of the data, submitted critical revisions of the manuscript for important intellectual content, and provided administrative, technical or material support for the study	participated in the study concept and design, carried out acquisition of the data, submitted critical revisions of the manuscript for important intellectual content, and provided administrative, technical or material support for the study	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Investigation|Methodology|Project administration|Resources|Writing - Review & Editing	YES
3022662	21156072	BS	2	carried out acquisition of the data and submitted critical revisions of the manuscript for important intellectual content	carried out acquisition of the data and submitted critical revisions of the manuscript for important intellectual content	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
3022662	21156072	CC	2	carried out acquisition of the data and provided administrative, technical or material support for the study	carried out acquisition of the data and provided administrative, technical or material support for the study	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Project administration|Resources	YES
3022662	21156072	DB	2	participated in the study concept and design, carried out acquisition of the data, submitted critical revisions of the manuscript for important intellectual content, supervised the study, and provided administrative, technical or material support for the study	participated in the study concept and design, carried out acquisition of the data, submitted critical revisions of the manuscript for important intellectual content, supervised the study, and provided administrative, technical or material support for the study	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Investigation|Methodology|Project administration|Resources|Supervision|Writing - Review & Editing	YES
3022662	21156072	DS	2	carried out acquisition of the data and submitted critical revisions of the manuscript for important intellectual content	carried out acquisition of the data and submitted critical revisions of the manuscript for important intellectual content	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
3022662	21156072	FT	2	carried out acquisition of the data and provided administrative, technical or material support for the study	carried out acquisition of the data and provided administrative, technical or material support for the study	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Project administration|Resources	YES
3022662	21156072	GDH	2	participated in the study concept and design, had full access to all of the data, carried out acquisition, analysis, and interpretation of the data, drafted the manuscript, supervised the study, and takes responsibility for the integrity of the data and the accuracy of the data analysis	participated in the study concept and design, had full access to all of the data, carried out acquisition, analysis, and interpretation of the data, drafted the manuscript, supervised the study, and takes responsibility for the integrity of the data and the accuracy of the data analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Data curation|Formal analysis|Investigation|Methodology|Supervision|Writing - Original Draft	YES
3022662	21156072	HK	2	participated in the study concept and design, carried out analysis and interpretation of the data, submitted critical revisions of the manuscript for important intellectual content, supervised the study, and provided administrative, technical or material support for the study	participated in the study concept and design, carried out analysis and interpretation of the data, submitted critical revisions of the manuscript for important intellectual content, supervised the study, and provided administrative, technical or material support for the study	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Project administration|Resources|Supervision|Writing - Review & Editing	YES
3022662	21156072	OA	2	carried out acquisition of the data	carried out acquisition of the data	Performed the experiments	Investigation	YES
3022662	21156072	PH	2	carried out acquisition of the data	carried out acquisition of the data	Performed the experiments	Investigation	YES
3022662	21156072	RL	2	carried out acquisition, analysis, and interpretation of the data, submitted critical revisions of the manuscript for important intellectual content, and provided administrative, technical or material support for the study	carried out acquisition, analysis, and interpretation of the data, submitted critical revisions of the manuscript for important intellectual content, and provided administrative, technical or material support for the study	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Project administration|Resources|Writing - Review & Editing	YES
3022662	21156072	SM	2	participated in the study concept and design, carried out acquisition, analysis, and interpretation of the data, and provided administrative, technical or material support for the study	participated in the study concept and design, carried out acquisition, analysis, and interpretation of the data, and provided administrative, technical or material support for the study	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Methodology|Project administration|Resources	YES
3022662	21156072	SV	2	carried out acquisition of the data,and provided administrative, technical or material support for the study	carried out acquisition of the data,and provided administrative, technical or material support for the study	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Project administration|Resources	YES
4401677	25885097	DAG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to the development of the manuscript|Read the manuscript|Approved the final version of the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401677	25885097	DAG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to the development of the manuscript|Read the manuscript|Approved the final version of the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4401677	25885097	DAG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to the development of the manuscript|Read the manuscript|Approved the final version of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4401677	25885097	DAG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to the development of the manuscript|Read the manuscript|Approved the final version of the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401677	25885097	DAG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to the development of the manuscript|Read the manuscript|Approved the final version of the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401677	25885097	DAG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to the development of the manuscript|Read the manuscript|Approved the final version of the manuscript	Contributed to the development of the manuscript	Wrote the paper	Writing - Original Draft	YES
4401677	25885097	DAG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to the development of the manuscript|Read the manuscript|Approved the final version of the manuscript	Read the manuscript	-	-	NO
4401677	25885097	DAG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to the development of the manuscript|Read the manuscript|Approved the final version of the manuscript	Approved the final version of the manuscript	-	-	NO
4401677	25885097	DD	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to the development of the manuscript|Read the manuscript|Approved the final version of the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401677	25885097	DD	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to the development of the manuscript|Read the manuscript|Approved the final version of the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401677	25885097	DD	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to the development of the manuscript|Read the manuscript|Approved the final version of the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401677	25885097	DD	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to the development of the manuscript|Read the manuscript|Approved the final version of the manuscript	Contributed to the development of the manuscript	Wrote the paper	Writing - Original Draft	YES
4401677	25885097	DD	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to the development of the manuscript|Read the manuscript|Approved the final version of the manuscript	Read the manuscript	-	-	NO
4401677	25885097	DD	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to the development of the manuscript|Read the manuscript|Approved the final version of the manuscript	Approved the final version of the manuscript	-	-	NO
4401677	25885097	EM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to the development of the manuscript|Read the manuscript|Approved the final version of the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4401677	25885097	EM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to the development of the manuscript|Read the manuscript|Approved the final version of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4401677	25885097	EM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to the development of the manuscript|Read the manuscript|Approved the final version of the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401677	25885097	EM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to the development of the manuscript|Read the manuscript|Approved the final version of the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401677	25885097	EM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to the development of the manuscript|Read the manuscript|Approved the final version of the manuscript	Contributed to the development of the manuscript	Wrote the paper	Writing - Original Draft	YES
4401677	25885097	EM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to the development of the manuscript|Read the manuscript|Approved the final version of the manuscript	Read the manuscript	-	-	NO
4401677	25885097	EM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to the development of the manuscript|Read the manuscript|Approved the final version of the manuscript	Approved the final version of the manuscript	-	-	NO
4401677	25885097	GA	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to the development of the manuscript|Read the manuscript|Approved the final version of the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4401677	25885097	GA	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to the development of the manuscript|Read the manuscript|Approved the final version of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4401677	25885097	GA	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to the development of the manuscript|Read the manuscript|Approved the final version of the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401677	25885097	GA	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to the development of the manuscript|Read the manuscript|Approved the final version of the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401677	25885097	GA	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to the development of the manuscript|Read the manuscript|Approved the final version of the manuscript	Contributed to the development of the manuscript	Wrote the paper	Writing - Original Draft	YES
4401677	25885097	GA	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to the development of the manuscript|Read the manuscript|Approved the final version of the manuscript	Read the manuscript	-	-	NO
4401677	25885097	GA	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to the development of the manuscript|Read the manuscript|Approved the final version of the manuscript	Approved the final version of the manuscript	-	-	NO
4401677	25885097	KK	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to the development of the manuscript|Read the manuscript|Approved the final version of the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4401677	25885097	KK	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to the development of the manuscript|Read the manuscript|Approved the final version of the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401677	25885097	KK	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to the development of the manuscript|Read the manuscript|Approved the final version of the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401677	25885097	KK	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to the development of the manuscript|Read the manuscript|Approved the final version of the manuscript	Contributed to the development of the manuscript	Wrote the paper	Writing - Original Draft	YES
4401677	25885097	KK	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to the development of the manuscript|Read the manuscript|Approved the final version of the manuscript	Read the manuscript	-	-	NO
4401677	25885097	KK	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to the development of the manuscript|Read the manuscript|Approved the final version of the manuscript	Approved the final version of the manuscript	-	-	NO
4401677	25885097	KPA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Contributed to the development of the manuscript|Read the manuscript|Approved the final version of the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401677	25885097	KPA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Contributed to the development of the manuscript|Read the manuscript|Approved the final version of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4401677	25885097	KPA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Contributed to the development of the manuscript|Read the manuscript|Approved the final version of the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401677	25885097	KPA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Contributed to the development of the manuscript|Read the manuscript|Approved the final version of the manuscript	Contributed to the development of the manuscript	Wrote the paper	Writing - Original Draft	YES
4401677	25885097	KPA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Contributed to the development of the manuscript|Read the manuscript|Approved the final version of the manuscript	Read the manuscript	-	-	NO
4401677	25885097	KPA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Contributed to the development of the manuscript|Read the manuscript|Approved the final version of the manuscript	Approved the final version of the manuscript	-	-	NO
4401677	25885097	LA	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to the development of the manuscript|Read the manuscript|Approved the final version of the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4401677	25885097	LA	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to the development of the manuscript|Read the manuscript|Approved the final version of the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401677	25885097	LA	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to the development of the manuscript|Read the manuscript|Approved the final version of the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401677	25885097	LA	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to the development of the manuscript|Read the manuscript|Approved the final version of the manuscript	Contributed to the development of the manuscript	Wrote the paper	Writing - Original Draft	YES
4401677	25885097	LA	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to the development of the manuscript|Read the manuscript|Approved the final version of the manuscript	Read the manuscript	-	-	NO
4401677	25885097	LA	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to the development of the manuscript|Read the manuscript|Approved the final version of the manuscript	Approved the final version of the manuscript	-	-	NO
4401677	25885097	NA	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to the development of the manuscript|Read the manuscript|Approved the final version of the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401677	25885097	NA	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to the development of the manuscript|Read the manuscript|Approved the final version of the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401677	25885097	NA	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to the development of the manuscript|Read the manuscript|Approved the final version of the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401677	25885097	NA	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to the development of the manuscript|Read the manuscript|Approved the final version of the manuscript	Contributed to the development of the manuscript	Wrote the paper	Writing - Original Draft	YES
4401677	25885097	NA	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to the development of the manuscript|Read the manuscript|Approved the final version of the manuscript	Read the manuscript	-	-	NO
4401677	25885097	NA	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to the development of the manuscript|Read the manuscript|Approved the final version of the manuscript	Approved the final version of the manuscript	-	-	NO
4401677	25885097	SA	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to the development of the manuscript|Read the manuscript|Approved the final version of the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4401677	25885097	SA	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to the development of the manuscript|Read the manuscript|Approved the final version of the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401677	25885097	SA	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to the development of the manuscript|Read the manuscript|Approved the final version of the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401677	25885097	SA	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to the development of the manuscript|Read the manuscript|Approved the final version of the manuscript	Contributed to the development of the manuscript	Wrote the paper	Writing - Original Draft	YES
4401677	25885097	SA	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to the development of the manuscript|Read the manuscript|Approved the final version of the manuscript	Read the manuscript	-	-	NO
4401677	25885097	SA	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to the development of the manuscript|Read the manuscript|Approved the final version of the manuscript	Approved the final version of the manuscript	-	-	NO
4401677	25885097	SKT	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to the development of the manuscript|Read the manuscript|Approved the final version of the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4401677	25885097	SKT	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to the development of the manuscript|Read the manuscript|Approved the final version of the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401677	25885097	SKT	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to the development of the manuscript|Read the manuscript|Approved the final version of the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401677	25885097	SKT	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to the development of the manuscript|Read the manuscript|Approved the final version of the manuscript	Contributed to the development of the manuscript	Wrote the paper	Writing - Original Draft	YES
4401677	25885097	SKT	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to the development of the manuscript|Read the manuscript|Approved the final version of the manuscript	Read the manuscript	-	-	NO
4401677	25885097	SKT	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to the development of the manuscript|Read the manuscript|Approved the final version of the manuscript	Approved the final version of the manuscript	-	-	NO
4401677	25885097	SN	PLoS5	Conceived and designed the experiments|Wrote the paper|Contributed to the development of the manuscript|Read the manuscript|Approved the final version of the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401677	25885097	SN	PLoS5	Conceived and designed the experiments|Wrote the paper|Contributed to the development of the manuscript|Read the manuscript|Approved the final version of the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401677	25885097	SN	PLoS5	Conceived and designed the experiments|Wrote the paper|Contributed to the development of the manuscript|Read the manuscript|Approved the final version of the manuscript	Contributed to the development of the manuscript	Wrote the paper	Writing - Original Draft	YES
4401677	25885097	SN	PLoS5	Conceived and designed the experiments|Wrote the paper|Contributed to the development of the manuscript|Read the manuscript|Approved the final version of the manuscript	Read the manuscript	-	-	NO
4401677	25885097	SN	PLoS5	Conceived and designed the experiments|Wrote the paper|Contributed to the development of the manuscript|Read the manuscript|Approved the final version of the manuscript	Approved the final version of the manuscript	-	-	NO
4401677	25885097	SOA	PLoS5	Conceived and designed the experiments|Wrote the paper|Contributed to the development of the manuscript|Read the manuscript|Approved the final version of the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401677	25885097	SOA	PLoS5	Conceived and designed the experiments|Wrote the paper|Contributed to the development of the manuscript|Read the manuscript|Approved the final version of the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401677	25885097	SOA	PLoS5	Conceived and designed the experiments|Wrote the paper|Contributed to the development of the manuscript|Read the manuscript|Approved the final version of the manuscript	Contributed to the development of the manuscript	Wrote the paper	Writing - Original Draft	YES
4401677	25885097	SOA	PLoS5	Conceived and designed the experiments|Wrote the paper|Contributed to the development of the manuscript|Read the manuscript|Approved the final version of the manuscript	Read the manuscript	-	-	NO
4401677	25885097	SOA	PLoS5	Conceived and designed the experiments|Wrote the paper|Contributed to the development of the manuscript|Read the manuscript|Approved the final version of the manuscript	Approved the final version of the manuscript	-	-	NO
4401677	25885097	VA	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to the development of the manuscript|Read the manuscript|Approved the final version of the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4401677	25885097	VA	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to the development of the manuscript|Read the manuscript|Approved the final version of the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401677	25885097	VA	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to the development of the manuscript|Read the manuscript|Approved the final version of the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401677	25885097	VA	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to the development of the manuscript|Read the manuscript|Approved the final version of the manuscript	Contributed to the development of the manuscript	Wrote the paper	Writing - Original Draft	YES
4401677	25885097	VA	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to the development of the manuscript|Read the manuscript|Approved the final version of the manuscript	Read the manuscript	-	-	NO
4401677	25885097	VA	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to the development of the manuscript|Read the manuscript|Approved the final version of the manuscript	Approved the final version of the manuscript	-	-	NO
4449883	26075265	Jiao Ren	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
4449883	26075265	Jie Peng	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
4449883	26075265	Tongxing Song	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
3022663	21159161	ACC	2	oversee acquisition of data and revised the manuscript critically for important intellectual content	oversee acquisition of data and revised the manuscript critically for important intellectual content	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Review & Editing	YES
3022663	21159161	ACJ	2	designed the study, interpreted the data, and drafted the manuscript	designed the study, interpreted the data, and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3022663	21159161	AR	2	oversee acquisition of data and revised the manuscript critically for important intellectual content	oversee acquisition of data and revised the manuscript critically for important intellectual content	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Review & Editing	YES
3022663	21159161	BR	2	oversee acquisition of data and revised the manuscript critically for important intellectual content	oversee acquisition of data and revised the manuscript critically for important intellectual content	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Review & Editing	YES
3022663	21159161	CAB	2	oversee acquisition of data and revised the manuscript critically for important intellectual content	oversee acquisition of data and revised the manuscript critically for important intellectual content	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Review & Editing	YES
3022663	21159161	JJE	2	oversee acquisition of data and revised the manuscript critically for important intellectual content	oversee acquisition of data and revised the manuscript critically for important intellectual content	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Review & Editing	YES
3022663	21159161	JJG	2	oversee acquisition of data and revised the manuscript critically for important intellectual content	oversee acquisition of data and revised the manuscript critically for important intellectual content	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Review & Editing	YES
3022663	21159161	JNM	2	oversee acquisition of data and revised the manuscript critically for important intellectual content	oversee acquisition of data and revised the manuscript critically for important intellectual content	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Review & Editing	YES
3022663	21159161	JT	2	oversee acquisition of data and revised the manuscript critically for important intellectual content	oversee acquisition of data and revised the manuscript critically for important intellectual content	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Review & Editing	YES
3022663	21159161	JTB	2	made substantial contributions to the design of the study, interpretation of the data, and revised the manuscript critically for important intellectual content	made substantial contributions to the design of the study, interpretation of the data, and revised the manuscript critically for important intellectual content	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Review & Editing	YES
3022663	21159161	KAG	2	designed the study, interpreted the data, and drafted the manuscript	designed the study, interpreted the data, and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3022663	21159161	KNA	2	designed the study, interpreted the data, and drafted the manuscript|also conducted the analysis	designed the study, interpreted the data, and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3022663	21159161	KNA	2	designed the study, interpreted the data, and drafted the manuscript|also conducted the analysis	also conducted the analysis	Performed the experiments	Investigation	YES
3022663	21159161	LPJ	2	oversee acquisition of data and revised the manuscript critically for important intellectual content	oversee acquisition of data and revised the manuscript critically for important intellectual content	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Review & Editing	YES
3022663	21159161	MAH	2	made substantial contributions to the design of the study, interpretation of the data, and revised the manuscript critically for important intellectual content	made substantial contributions to the design of the study, interpretation of the data, and revised the manuscript critically for important intellectual content	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Review & Editing	YES
3022663	21159161	MBK	2	made substantial contributions to the design of the study, interpretation of the data, and revised the manuscript critically for important intellectual content	made substantial contributions to the design of the study, interpretation of the data, and revised the manuscript critically for important intellectual content	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Review & Editing	YES
3022663	21159161	MJG	2	oversee acquisition of data and revised the manuscript critically for important intellectual content	oversee acquisition of data and revised the manuscript critically for important intellectual content	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Review & Editing	YES
3022663	21159161	MJS	2	oversee acquisition of data and revised the manuscript critically for important intellectual content	oversee acquisition of data and revised the manuscript critically for important intellectual content	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Review & Editing	YES
3022663	21159161	MMK	2	oversee acquisition of data and revised the manuscript critically for important intellectual content	oversee acquisition of data and revised the manuscript critically for important intellectual content	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Review & Editing	YES
3022663	21159161	MSS	2	oversee acquisition of data and revised the manuscript critically for important intellectual content	oversee acquisition of data and revised the manuscript critically for important intellectual content	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Review & Editing	YES
3022663	21159161	RDM	2	designed the study, interpreted the data, and drafted the manuscript	designed the study, interpreted the data, and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3022663	21159161	RGM	2	oversee acquisition of data and revised the manuscript critically for important intellectual content	oversee acquisition of data and revised the manuscript critically for important intellectual content	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Review & Editing	YES
3022663	21159161	RJB	2	made substantial contributions to the design of the study, interpretation of the data, and revised the manuscript critically for important intellectual content	made substantial contributions to the design of the study, interpretation of the data, and revised the manuscript critically for important intellectual content	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Review & Editing	YES
3022663	21159161	RSH	2	made substantial contributions to the design of the study, interpretation of the data, and revised the manuscript critically for important intellectual content	made substantial contributions to the design of the study, interpretation of the data, and revised the manuscript critically for important intellectual content	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Review & Editing	YES
3022663	21159161	SBR	2	oversee acquisition of data and revised the manuscript critically for important intellectual content	oversee acquisition of data and revised the manuscript critically for important intellectual content	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Review & Editing	YES
3022663	21159161	SDK	2	oversee acquisition of data and revised the manuscript critically for important intellectual content	oversee acquisition of data and revised the manuscript critically for important intellectual content	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Review & Editing	YES
3022663	21159161	SGD	2	oversee acquisition of data and revised the manuscript critically for important intellectual content	oversee acquisition of data and revised the manuscript critically for important intellectual content	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Review & Editing	YES
3022663	21159161	SJG	2	designed the study, interpreted the data, and drafted the manuscript	designed the study, interpreted the data, and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3022663	21159161	SN	2	oversee acquisition of data and revised the manuscript critically for important intellectual content	oversee acquisition of data and revised the manuscript critically for important intellectual content	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Review & Editing	YES
3022663	21159161	TRS	2	oversee acquisition of data and revised the manuscript critically for important intellectual content	oversee acquisition of data and revised the manuscript critically for important intellectual content	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Review & Editing	YES
5116198	27863461	AG	2	contributed to acquisition of additional data, and critical revision of manuscript	contributed to acquisition of additional data, and critical revision of manuscript	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Resources|Writing - Review & Editing	YES
5116198	27863461	AR	2	contributed to data acquisition and critical manuscript revision	contributed to data acquisition and critical manuscript revision	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5116198	27863461	DS	2	contributed to data acquisition and critical manuscript revision	contributed to data acquisition and critical manuscript revision	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5116198	27863461	GWM	2	contributed to conception and design of the study, analysis and interpretation of data and draft revision	contributed to conception and design of the study, analysis and interpretation of data and draft revision	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5116198	27863461	JEC	2	contributed to conception and design of the study, analysis and interpretation of data and draft revision	contributed to conception and design of the study, analysis and interpretation of data and draft revision	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5116198	27863461	JJK	2	contributed to conception and design, acquisition, analysis and interpretation of data and manuscript draft preparation	contributed to conception and design, acquisition, analysis and interpretation of data and manuscript draft preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Resources|Writing - Original Draft	YES
5116198	27863461	JW	2	contributed to acquisition of additional data, and critical revision of manuscript	contributed to acquisition of additional data, and critical revision of manuscript	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Resources|Writing - Review & Editing	YES
5116198	27863461	KL	2	contributed to acquisition and processing of data	contributed to acquisition and processing of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Investigation|Resources	YES
5116198	27863461	KPB	2	contributed to conception and design of the study, analysis and interpretation of data and draft revision	contributed to conception and design of the study, analysis and interpretation of data and draft revision	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5116198	27863461	LL	2	contributed to acquisition and processing of data	contributed to acquisition and processing of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Investigation|Resources	YES
5116198	27863461	MD	2	contributed to data acquisition and critical manuscript revision	contributed to data acquisition and critical manuscript revision	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5116198	27863461	PNB	2	contributed to acquisition of additional data, and critical revision of manuscript	contributed to acquisition of additional data, and critical revision of manuscript	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Resources|Writing - Review & Editing	YES
5116198	27863461	PRE	2	contributed to data acquisition and critical manuscript revision	contributed to data acquisition and critical manuscript revision	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5116198	27863461	PSH	2	contributed to data acquisition and critical manuscript revision	contributed to data acquisition and critical manuscript revision	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5116198	27863461	RW	2	contributed to data acquisition and critical manuscript revision	contributed to data acquisition and critical manuscript revision	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5116198	27863461	SF	2	contributed to data acquisition and critical manuscript revision|contributed to data acquisition and critical manuscript revision	contributed to data acquisition and critical manuscript revision	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5116198	27863461	SF	2	contributed to data acquisition and critical manuscript revision|contributed to data acquisition and critical manuscript revision	contributed to data acquisition and critical manuscript revision	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5116198	27863461	SM	2	contributed to conception and design of the study, analysis and interpretation of data and draft revision	contributed to conception and design of the study, analysis and interpretation of data and draft revision	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5116198	27863461	SS	2	contributed to acquisition of additional data, and critical revision of manuscript	contributed to acquisition of additional data, and critical revision of manuscript	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Resources|Writing - Review & Editing	YES
5116198	27863461	YL	2	contributed to conception and design of the study, analysis and interpretation of data and draft revision	contributed to conception and design of the study, analysis and interpretation of data and draft revision	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5478899	28680433	DZ	2	conceived and designed the experiment|revised the manuscript|obtained funding and is responsible for this article	conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5478899	28680433	DZ	2	conceived and designed the experiment|revised the manuscript|obtained funding and is responsible for this article	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5478899	28680433	DZ	2	conceived and designed the experiment|revised the manuscript|obtained funding and is responsible for this article	obtained funding and is responsible for this article	-	Funding acquisition	YES
5478899	28680433	JC	2	provided valuable suggestions for the manuscript	provided valuable suggestions for the manuscript	-	-	NO
5478899	28680433	JX	2	provided valuable suggestions for the manuscript	provided valuable suggestions for the manuscript	-	-	NO
5478899	28680433	LX	2	collected the data and conducted statistical analysis|wrote the manuscript	collected the data and conducted statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5478899	28680433	LX	2	collected the data and conducted statistical analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5478899	28680433	MQ	2	collected the data and conducted statistical analysis|provided valuable suggestions for the manuscript|revised the manuscript	collected the data and conducted statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5478899	28680433	MQ	2	collected the data and conducted statistical analysis|provided valuable suggestions for the manuscript|revised the manuscript	provided valuable suggestions for the manuscript	-	-	NO
5478899	28680433	MQ	2	collected the data and conducted statistical analysis|provided valuable suggestions for the manuscript|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5478899	28680433	QD	2	provided valuable suggestions for the manuscript|revised the manuscript	provided valuable suggestions for the manuscript	-	-	NO
5478899	28680433	QD	2	provided valuable suggestions for the manuscript|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
3022664	21176160	AK	7	Data analysis and write up	Data analysis and write up	Analyzed the data|Wrote the paper	Formal analysis	YES
3022664	21176160	AM	7	Study design and write up	Study design and write up	Conceived and designed the experiments|Wrote the paper	Methodology	YES
3022664	21176160	KH	7	Study design, data collection, data analysis and write up	Study design, data collection, data analysis and write up	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology	YES
3022664	21176160	YW	7	write up	write up	Wrote the paper	-	YES
4401678	25885967	BJAP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401678	25885967	BJAP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401678	25885967	BJAP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401678	25885967	BMCG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401678	25885967	BMCG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401678	25885967	BMCG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401678	25885967	BMCG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401678	25885967	ESB	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401678	25885967	ESB	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401678	25885967	WCEPV	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5117502	27871228	BB	2	conceived the idea|designed the study|did the bio-informatic analysis|did the experimental part|prepared the manuscript	conceived the idea	Conceived and designed the experiments	Conceptualization	YES
5117502	27871228	BB	2	conceived the idea|designed the study|did the bio-informatic analysis|did the experimental part|prepared the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5117502	27871228	BB	2	conceived the idea|designed the study|did the bio-informatic analysis|did the experimental part|prepared the manuscript	did the bio-informatic analysis	-	Formal analysis	YES
5117502	27871228	BB	2	conceived the idea|designed the study|did the bio-informatic analysis|did the experimental part|prepared the manuscript	did the experimental part	Performed the experiments	Investigation	YES
5117502	27871228	BB	2	conceived the idea|designed the study|did the bio-informatic analysis|did the experimental part|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5117502	27871228	MK	2	did the experimental part	did the experimental part	Performed the experiments	Investigation	YES
5117502	27871228	PV	2	conceived the idea|designed the study|prepared the manuscript	conceived the idea	Conceived and designed the experiments	Conceptualization	YES
5117502	27871228	PV	2	conceived the idea|designed the study|prepared the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5117502	27871228	PV	2	conceived the idea|designed the study|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5117502	27871228	UKJ	2	did the bio-informatic analysis	did the bio-informatic analysis	-	Formal analysis	YES
3022665	21190572	All authors	2	contributed to the manuscript and approved its final version	contributed to the manuscript and approved its final version	-	-	NO
3022665	21190572	GCG	2	designed the study and participated in data collection	designed the study and participated in data collection	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3022665	21190572	HDM	2	analysed the data and wrote the first draft of the manuscript	analysed the data and wrote the first draft of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3022665	21190572	JH	2	analysed the data and wrote the first draft of the manuscript	analysed the data and wrote the first draft of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3022665	21190572	WM	2	designed the study and participated in data collection	designed the study and participated in data collection	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4401680	25885536	CQW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401680	25885536	HX	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401680	25885536	LB	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401680	25885536	LLD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401680	25885536	LLD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401680	25885536	LLD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401680	25885536	WS	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401680	25885536	XFW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401680	25885536	YM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401680	25885536	YYS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401680	25885536	YYS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401680	25885536	YYS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401680	25885536	YYS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5479058	28680438	ABA	2	lipid peroxidation analyses	lipid peroxidation analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5479058	28680438	All authors	2	revised and approved the final manuscript	revised and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5479058	28680438	CM	2	contributed to the design of the study and interpretation of the results, supervised all the study and revised the manuscript	contributed to the design of the study and interpretation of the results, supervised all the study and revised the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Supervision|Writing - Review & Editing	YES
5479058	28680438	CT	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5479058	28680438	DB	2	supervised all the analyses and drafted the manuscript	supervised all the analyses and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Supervision|Writing - Original Draft	YES
4324689	25729582	Kelsey L. Dillehay	2	conducted experiments|performed data analysis|wrote or contributed to the writing of the manuscript	conducted experiments	Performed the experiments	Investigation	YES
4324689	25729582	Kelsey L. Dillehay	2	conducted experiments|performed data analysis|wrote or contributed to the writing of the manuscript	performed data analysis	Analyzed the data	Formal analysis	YES
4324689	25729582	Kelsey L. Dillehay	2	conducted experiments|performed data analysis|wrote or contributed to the writing of the manuscript	wrote or contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
4324689	25729582	Shan Lu	2	participated in research design|performed data analysis|wrote or contributed to the writing of the manuscript	participated in research design	Conceived and designed the experiments	-	YES
4324689	25729582	Shan Lu	2	participated in research design|performed data analysis|wrote or contributed to the writing of the manuscript	performed data analysis	Analyzed the data	Formal analysis	YES
4324689	25729582	Shan Lu	2	participated in research design|performed data analysis|wrote or contributed to the writing of the manuscript	wrote or contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
4324689	25729582	William L. Seibel	2	conducted experiments|performed data analysis|wrote or contributed to the writing of the manuscript	conducted experiments	Performed the experiments	Investigation	YES
4324689	25729582	William L. Seibel	2	conducted experiments|performed data analysis|wrote or contributed to the writing of the manuscript	performed data analysis	Analyzed the data	Formal analysis	YES
4324689	25729582	William L. Seibel	2	conducted experiments|performed data analysis|wrote or contributed to the writing of the manuscript	wrote or contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
4324689	25729582	Zhongyun Dong	2	participated in research design|conducted experiments|performed data analysis|wrote or contributed to the writing of the manuscript	participated in research design	Conceived and designed the experiments	-	YES
4324689	25729582	Zhongyun Dong	2	participated in research design|conducted experiments|performed data analysis|wrote or contributed to the writing of the manuscript	conducted experiments	Performed the experiments	Investigation	YES
4324689	25729582	Zhongyun Dong	2	participated in research design|conducted experiments|performed data analysis|wrote or contributed to the writing of the manuscript	performed data analysis	Analyzed the data	Formal analysis	YES
4324689	25729582	Zhongyun Dong	2	participated in research design|conducted experiments|performed data analysis|wrote or contributed to the writing of the manuscript	wrote or contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5117530	27871224	BR	2	carried out the cellular cultures, flow cytometry and differentiation assays, sequencing and microarray steps, data analysis and drafted the manuscript|designed the study	carried out the cellular cultures, flow cytometry and differentiation assays, sequencing and microarray steps, data analysis and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5117530	27871224	BR	2	carried out the cellular cultures, flow cytometry and differentiation assays, sequencing and microarray steps, data analysis and drafted the manuscript|designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5117530	27871224	CC	2	procured the extraction of human samples, participated in the coordination of the study and helped draft the manuscript	procured the extraction of human samples, participated in the coordination of the study and helped draft the manuscript	Wrote the paper	Project administration|Writing - Original Draft	YES
5117530	27871224	FSG	2	procured the extraction of human samples, participated in the coordination of the study and helped draft the manuscript	procured the extraction of human samples, participated in the coordination of the study and helped draft the manuscript	Wrote the paper	Project administration|Writing - Original Draft	YES
5117530	27871224	JDLR	2	designed the study|supervised the experimental work and the data analysis, coordinated the study and corrected the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5117530	27871224	JDLR	2	designed the study|supervised the experimental work and the data analysis, coordinated the study and corrected the manuscript	supervised the experimental work and the data analysis, coordinated the study and corrected the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Project administration|Supervision|Writing - Review & Editing	YES
3033792	21226969	AT	2	constructed the plasmids and performed the fluorescent reporter assays	constructed the plasmids and performed the fluorescent reporter assays	Performed the experiments	Investigation	YES
3033792	21226969	GJM	2	conceived the experiments|constructed the plasmids and performed the fluorescent reporter assays|analyzed and interpreted the results	conceived the experiments	Conceived and designed the experiments	Conceptualization	YES
3033792	21226969	GJM	2	conceived the experiments|constructed the plasmids and performed the fluorescent reporter assays|analyzed and interpreted the results	constructed the plasmids and performed the fluorescent reporter assays	Performed the experiments	Investigation	YES
3033792	21226969	GJM	2	conceived the experiments|constructed the plasmids and performed the fluorescent reporter assays|analyzed and interpreted the results	analyzed and interpreted the results	Analyzed the data	Formal analysis	YES
3033792	21226969	JLG	2	constructed the plasmids and performed the fluorescent reporter assays	constructed the plasmids and performed the fluorescent reporter assays	Performed the experiments	Investigation	YES
3033792	21226969	TLA	2	conceived the experiments|analyzed and interpreted the results	conceived the experiments	Conceived and designed the experiments	Conceptualization	YES
3033792	21226969	TLA	2	conceived the experiments|analyzed and interpreted the results	analyzed and interpreted the results	Analyzed the data	Formal analysis	YES
3033792	21226969	YY	2	constructed the plasmids and performed the fluorescent reporter assays	constructed the plasmids and performed the fluorescent reporter assays	Performed the experiments	Investigation	YES
5479884	28690627	FH	PLoS52	designed the study|performed the experiments|analyzed the data|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5479884	28690627	FH	PLoS52	designed the study|performed the experiments|analyzed the data|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5479884	28690627	FH	PLoS52	designed the study|performed the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5479884	28690627	FH	PLoS52	designed the study|performed the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5479884	28690627	MS	PLoS52	designed the study|contributed reagents/materials/analysis tools|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5479884	28690627	MS	PLoS52	designed the study|contributed reagents/materials/analysis tools|wrote the manuscript	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5479884	28690627	MS	PLoS52	designed the study|contributed reagents/materials/analysis tools|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4401682	25885062	AKP	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401682	25885062	BHA	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401682	25885062	BHA	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401682	25885062	BHA	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401682	25885062	EAS	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401682	25885062	GMN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401682	25885062	GMN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401682	25885062	GMN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401682	25885062	GMN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401682	25885062	PKC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401682	25885062	PKC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401682	25885062	PKC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401682	25885062	VER	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401682	25885062	VSB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401682	25885062	VSB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401682	25885062	VSB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401682	25885062	VSB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3037838	21244701	AG	2	helped to implement the study, including data collection and oversight at the individual study sites at which participants were followed|participated in discussions concerning the design of this project, provided feedback and suggestions on interim analyses, and offered valuable input and recommendations on draft versions of this manuscript	helped to implement the study, including data collection and oversight at the individual study sites at which participants were followed	Performed the experiments	Investigation|Supervision	YES
3037838	21244701	AG	2	helped to implement the study, including data collection and oversight at the individual study sites at which participants were followed|participated in discussions concerning the design of this project, provided feedback and suggestions on interim analyses, and offered valuable input and recommendations on draft versions of this manuscript	participated in discussions concerning the design of this project, provided feedback and suggestions on interim analyses, and offered valuable input and recommendations on draft versions of this manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3037838	21244701	AL	2	was lead author on planning and coordinating the analysis, and drafting interim and final versions of the manuscript	was lead author on planning and coordinating the analysis, and drafting interim and final versions of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft	YES
3037838	21244701	AW	2	helped to implement the study, including data collection and oversight at the individual study sites at which participants were followed|participated in discussions concerning the design of this project, provided feedback and suggestions on interim analyses, and offered valuable input and recommendations on draft versions of this manuscript	helped to implement the study, including data collection and oversight at the individual study sites at which participants were followed	Performed the experiments	Investigation|Supervision	YES
3037838	21244701	AW	2	helped to implement the study, including data collection and oversight at the individual study sites at which participants were followed|participated in discussions concerning the design of this project, provided feedback and suggestions on interim analyses, and offered valuable input and recommendations on draft versions of this manuscript	participated in discussions concerning the design of this project, provided feedback and suggestions on interim analyses, and offered valuable input and recommendations on draft versions of this manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3037838	21244701	BA	2	helped to implement the study, including data collection and oversight at the individual study sites at which participants were followed|participated in discussions concerning the design of this project, provided feedback and suggestions on interim analyses, and offered valuable input and recommendations on draft versions of this manuscript	helped to implement the study, including data collection and oversight at the individual study sites at which participants were followed	Performed the experiments	Investigation|Supervision	YES
3037838	21244701	BA	2	helped to implement the study, including data collection and oversight at the individual study sites at which participants were followed|participated in discussions concerning the design of this project, provided feedback and suggestions on interim analyses, and offered valuable input and recommendations on draft versions of this manuscript	participated in discussions concerning the design of this project, provided feedback and suggestions on interim analyses, and offered valuable input and recommendations on draft versions of this manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3037838	21244701	EK	2	conducted and/or provided guidance with various aspects of the statistical analysis|participated in discussions concerning the design of this project, provided feedback and suggestions on interim analyses, and offered valuable input and recommendations on draft versions of this manuscript	conducted and/or provided guidance with various aspects of the statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Supervision	YES
3037838	21244701	EK	2	conducted and/or provided guidance with various aspects of the statistical analysis|participated in discussions concerning the design of this project, provided feedback and suggestions on interim analyses, and offered valuable input and recommendations on draft versions of this manuscript	participated in discussions concerning the design of this project, provided feedback and suggestions on interim analyses, and offered valuable input and recommendations on draft versions of this manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3037838	21244701	LE	2	conducted and/or provided guidance with various aspects of the statistical analysis|participated in discussions concerning the design of this project, provided feedback and suggestions on interim analyses, and offered valuable input and recommendations on draft versions of this manuscript	conducted and/or provided guidance with various aspects of the statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Supervision	YES
3037838	21244701	LE	2	conducted and/or provided guidance with various aspects of the statistical analysis|participated in discussions concerning the design of this project, provided feedback and suggestions on interim analyses, and offered valuable input and recommendations on draft versions of this manuscript	participated in discussions concerning the design of this project, provided feedback and suggestions on interim analyses, and offered valuable input and recommendations on draft versions of this manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3037838	21244701	MD	2	participated in discussions concerning the design of this project, provided feedback and suggestions on interim analyses, and offered valuable input and recommendations on draft versions of this manuscript	participated in discussions concerning the design of this project, provided feedback and suggestions on interim analyses, and offered valuable input and recommendations on draft versions of this manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3037838	21244701	NC	2	helped to implement the study, including data collection and oversight at the individual study sites at which participants were followed|participated in discussions concerning the design of this project, provided feedback and suggestions on interim analyses, and offered valuable input and recommendations on draft versions of this manuscript	helped to implement the study, including data collection and oversight at the individual study sites at which participants were followed	Performed the experiments	Investigation|Supervision	YES
3037838	21244701	NC	2	helped to implement the study, including data collection and oversight at the individual study sites at which participants were followed|participated in discussions concerning the design of this project, provided feedback and suggestions on interim analyses, and offered valuable input and recommendations on draft versions of this manuscript	participated in discussions concerning the design of this project, provided feedback and suggestions on interim analyses, and offered valuable input and recommendations on draft versions of this manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3037838	21244701	PG	2	conducted and/or provided guidance with various aspects of the statistical analysis|participated in discussions concerning the design of this project, provided feedback and suggestions on interim analyses, and offered valuable input and recommendations on draft versions of this manuscript	conducted and/or provided guidance with various aspects of the statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Supervision	YES
3037838	21244701	PG	2	conducted and/or provided guidance with various aspects of the statistical analysis|participated in discussions concerning the design of this project, provided feedback and suggestions on interim analyses, and offered valuable input and recommendations on draft versions of this manuscript	participated in discussions concerning the design of this project, provided feedback and suggestions on interim analyses, and offered valuable input and recommendations on draft versions of this manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3037838	21244701	VM	2	helped to implement the study, including data collection and oversight at the individual study sites at which participants were followed|participated in discussions concerning the design of this project, provided feedback and suggestions on interim analyses, and offered valuable input and recommendations on draft versions of this manuscript	helped to implement the study, including data collection and oversight at the individual study sites at which participants were followed	Performed the experiments	Investigation|Supervision	YES
3037838	21244701	VM	2	helped to implement the study, including data collection and oversight at the individual study sites at which participants were followed|participated in discussions concerning the design of this project, provided feedback and suggestions on interim analyses, and offered valuable input and recommendations on draft versions of this manuscript	participated in discussions concerning the design of this project, provided feedback and suggestions on interim analyses, and offered valuable input and recommendations on draft versions of this manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5117540	27871222	AZ	2	carried out the field experiments	carried out the field experiments	Performed the experiments	Investigation	YES
5117540	27871222	CQ	2	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5117540	27871222	JL	2	analyzed data|carried out the field experiments	analyzed data	Analyzed the data	Formal analysis	YES
5117540	27871222	JL	2	analyzed data|carried out the field experiments	carried out the field experiments	Performed the experiments	Investigation	YES
5117540	27871222	XY	2	designed the study and wrote the manuscript	designed the study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5117540	27871222	YH	2	designed the study and wrote the manuscript	designed the study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5117540	27871222	YR	2	carried out the field experiments	carried out the field experiments	Performed the experiments	Investigation	YES
5117540	27871222	ZC	2	analyzed data|carried out the field experiments	analyzed data	Analyzed the data	Formal analysis	YES
5117540	27871222	ZC	2	analyzed data|carried out the field experiments	carried out the field experiments	Performed the experiments	Investigation	YES
5479900	28690630	G-QZ	2	prepared the final datasets	prepared the final datasets	-	-	NO
5479900	28690630	J-YW	2	analyzed and acquired the data	analyzed and acquired the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5479900	28690630	JH	2	collected the plant materials	collected the plant materials	Performed the experiments	Investigation	YES
5479900	28690630	P-XL	2	collected the plant materials	collected the plant materials	Performed the experiments	Investigation	YES
5479900	28690630	QX	2	analyzed and acquired the data	analyzed and acquired the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5479900	28690630	S-CN	2	conceived and designed the study|prepared the final datasets|analyzed and acquired the data|collected the plant materials|wrote the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5479900	28690630	S-CN	2	conceived and designed the study|prepared the final datasets|analyzed and acquired the data|collected the plant materials|wrote the manuscript	prepared the final datasets	-	-	NO
5479900	28690630	S-CN	2	conceived and designed the study|prepared the final datasets|analyzed and acquired the data|collected the plant materials|wrote the manuscript	analyzed and acquired the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5479900	28690630	S-CN	2	conceived and designed the study|prepared the final datasets|analyzed and acquired the data|collected the plant materials|wrote the manuscript	collected the plant materials	Performed the experiments	Investigation	YES
5479900	28690630	S-CN	2	conceived and designed the study|prepared the final datasets|analyzed and acquired the data|collected the plant materials|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5479900	28690630	Y-BL	2	conceived and designed the study|wrote the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5479900	28690630	Y-BL	2	conceived and designed the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5479900	28690630	Y-QZ	2	analyzed and acquired the data	analyzed and acquired the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5479900	28690630	Z-JL	2	conceived and designed the study|wrote the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5479900	28690630	Z-JL	2	conceived and designed the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3038877	21255437	BES-B	2	designed and supervised the study	designed and supervised the study	Conceived and designed the experiments	Methodology|Supervision	YES
3038877	21255437	KM	2	conducted the histopathology evaluations and the correlations with serum chemistries	conducted the histopathology evaluations and the correlations with serum chemistries	Performed the experiments	Investigation	YES
3038877	21255437	LR	2	performed the veterinary supervision, clinical observations and therapeutic interventions on the animals	performed the veterinary supervision, clinical observations and therapeutic interventions on the animals	Performed the experiments	Investigation|Supervision	YES
3038877	21255437	RNA	2	viral loads	viral loads	-	-	NO
3038877	21255437	YES	2	designed and supervised the study	designed and supervised the study	Conceived and designed the experiments	Methodology|Supervision	YES
4401684	25885090	HF	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401684	25885090	LW	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401684	25885090	LW	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401684	25885090	SY	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401684	25885090	TW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401684	25885090	TW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401684	25885090	TW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401684	25885090	TW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3038878	21269430	AS	2	conceptualised the study, participated in the design and coordination and helped to draft the manuscript	conceptualised the study, participated in the design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
3038878	21269430	All authors	2	revised the script critically and read and approved the final manuscript	revised the script critically and read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
3038878	21269430	BC	2	participated in design and drafted the manuscript	participated in design and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
3038878	21269430	KC	2	made a contribution to conception and design|performed statistical analysis	made a contribution to conception and design	Conceived and designed the experiments	Conceptualization	YES
3038878	21269430	KC	2	made a contribution to conception and design|performed statistical analysis	performed statistical analysis	Analyzed the data	Formal analysis	YES
3038878	21269430	MB	2	made a contribution to conception and design	made a contribution to conception and design	Conceived and designed the experiments	Conceptualization	YES
5117568	27871227	BG	2	were involved in dna sample analysis	were involved in dna sample analysis	Analyzed the data	Formal analysis	YES
5117568	27871227	FT	2	carried out the genetic diversity analysis and drafted the manuscript|were involved in dna sample analysis	carried out the genetic diversity analysis and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5117568	27871227	FT	2	carried out the genetic diversity analysis and drafted the manuscript|were involved in dna sample analysis	were involved in dna sample analysis	Analyzed the data	Formal analysis	YES
5117568	27871227	NDA	2	performed part of the bioinformatic analysis|contributed to the writing of the manuscript and jointly supervised the work	performed part of the bioinformatic analysis	Performed the experiments	Formal analysis|Investigation	YES
5117568	27871227	NDA	2	performed part of the bioinformatic analysis|contributed to the writing of the manuscript and jointly supervised the work	contributed to the writing of the manuscript and jointly supervised the work	Wrote the paper	Supervision|Writing - Original Draft	YES
5117568	27871227	PT	2	contributed to the writing of the manuscript and jointly supervised the work|conceived and coordinated the work	contributed to the writing of the manuscript and jointly supervised the work	Wrote the paper	Supervision|Writing - Original Draft	YES
5117568	27871227	PT	2	contributed to the writing of the manuscript and jointly supervised the work|conceived and coordinated the work	conceived and coordinated the work	Conceived and designed the experiments	Conceptualization|Project administration	YES
5117568	27871227	TC	2	revised the manuscript and contributed to the interpretation of data	revised the manuscript and contributed to the interpretation of data	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
4448987	26038702	A.V.P.	PLoS52	performed the research	performed the research	Performed the experiments	Investigation	YES
4448987	26038702	C.R.G.	PLoS52	performed the research|wrote the paper	performed the research	Performed the experiments	Investigation	YES
4448987	26038702	C.R.G.	PLoS52	performed the research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4448987	26038702	I.K.	PLoS52	performed the research|designed the research study|analyzed the data|wrote the paper	performed the research	Performed the experiments	Investigation	YES
4448987	26038702	I.K.	PLoS52	performed the research|designed the research study|analyzed the data|wrote the paper	designed the research study	Conceived and designed the experiments	Methodology	YES
4448987	26038702	I.K.	PLoS52	performed the research|designed the research study|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
4448987	26038702	I.K.	PLoS52	performed the research|designed the research study|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4448987	26038702	J.F.P.	PLoS52	designed the research study|analyzed the data	designed the research study	Conceived and designed the experiments	Methodology	YES
4448987	26038702	J.F.P.	PLoS52	designed the research study|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
4448987	26038702	M.G.	PLoS52	performed the research	performed the research	Performed the experiments	Investigation	YES
4448987	26038702	S.O.	PLoS52	performed the research	performed the research	Performed the experiments	Investigation	YES
4448987	26038702	V.B.	PLoS52	designed the research study|analyzed the data|wrote the paper	designed the research study	Conceived and designed the experiments	Methodology	YES
4448987	26038702	V.B.	PLoS52	designed the research study|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
4448987	26038702	V.B.	PLoS52	designed the research study|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5479913	28690617	PV	1	Study was conceived and designed by|Manuscript prepared by	Study was conceived and designed by	Conceived and designed the experiments	Conceptualization|Methodology	YES
5479913	28690617	PV	1	Study was conceived and designed by|Manuscript prepared by	Manuscript prepared by	Wrote the paper	Writing - Original Draft	YES
5479913	28690617	SF	1	Manuscript prepared by	Manuscript prepared by	Wrote the paper	Writing - Original Draft	YES
5479913	28690617	SG	1	Study was conceived and designed by|Manuscript prepared by	Study was conceived and designed by	Conceived and designed the experiments	Conceptualization|Methodology	YES
5479913	28690617	SG	1	Study was conceived and designed by|Manuscript prepared by	Manuscript prepared by	Wrote the paper	Writing - Original Draft	YES
5479913	28690617	UR	1	Manuscript prepared by	Manuscript prepared by	Wrote the paper	Writing - Original Draft	YES
4401685	25884726	DKZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401685	25884726	DKZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401685	25884726	DKZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401685	25884726	GHC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401685	25884726	JLW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401685	25884726	LL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401685	25884726	MS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401685	25884726	MS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401685	25884726	MS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401685	25884726	QQ	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4401685	25884726	QQ	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401685	25884726	TL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4401685	25884726	TL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401685	25884726	ZWZ	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401685	25884726	ZWZ	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3038879	21272358	AI	2	conceived the design of the study, performed and interpreted the statistical analysis and helped to draft the manuscript	conceived the design of the study, performed and interpreted the statistical analysis and helped to draft the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
3038879	21272358	DE	2	participated in the coordination of the study, assisted with the statistical analysis and helped to draft the manuscript	participated in the coordination of the study, assisted with the statistical analysis and helped to draft the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Project administration|Writing - Original Draft	YES
3038879	21272358	EP	2	assisted with development and interpretation of the statistical analysis and helped to draft the manuscript	assisted with development and interpretation of the statistical analysis and helped to draft the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3038879	21272358	FS	2	participated in the design of the study and helped to draft the manuscript	participated in the design of the study and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3038879	21272358	MS	2	conceived the design of the study, performed and interpreted the statistical analysis and helped to draft the manuscript	conceived the design of the study, performed and interpreted the statistical analysis and helped to draft the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
3038879	21272358	WC	2	participated in the coordination of the study, assisted with the statistical analysis and helped to draft the manuscript	participated in the coordination of the study, assisted with the statistical analysis and helped to draft the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Project administration|Writing - Original Draft	YES
5479915	28690626	Agricultural Research	2	that provided the seeds and the experimental test	that provided the seeds and the experimental test	-	-	NO
5479915	28690626	The authors	2	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	Performed the experiments	Investigation	YES
4401687	25884725	BO	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401687	25884725	BO	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401687	25884725	KH	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401687	25884725	KH	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401687	25884725	KI	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401687	25884725	KI	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401687	25884725	KM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401687	25884725	KM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401687	25884725	KM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401687	25884725	KO	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401687	25884725	KO	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401687	25884725	OT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401687	25884725	OT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401687	25884725	OT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401687	25884725	OT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401687	25884725	OT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5117596	27871231	AG	2	provided all microscopic images used in fig	provided all microscopic images used in fig	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
5117596	27871231	All authors	2	reviewed and revised the final manuscript before submission	reviewed and revised the final manuscript before submission	Wrote the paper	Writing - Review & Editing	YES
5117596	27871231	CDS	2	from transcriptome data and did all transcriptome statistics and analyses	from transcriptome data and did all transcriptome statistics and analyses	Analyzed the data	Formal analysis	YES
5117596	27871231	CL	2	provided ideas and collected worms for proteomics and transcriptomics experiments and performed one of the starvation experiments	provided ideas and collected worms for proteomics and transcriptomics experiments and performed one of the starvation experiments	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5117596	27871231	JCY	2	provided ideas and ran 2d-lc-ms/ms experiments	provided ideas and ran 2d-lc-ms/ms experiments	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5117596	27871231	JW	2	contributed equally to this manuscript	contributed equally to this manuscript	-	-	NO
5117596	27871231	MK	2	contributed equally to this manuscript|conceived the study and the manuscript, edited the manuscript and provided ideas, conceived proteomics experiments, collected worms for proteomics experiments and performed two of the starvation experiments, compiled the protein reference database, did statistical analyses and processed and analyzed the proteomics data	contributed equally to this manuscript	-	-	NO
5117596	27871231	MK	2	contributed equally to this manuscript|conceived the study and the manuscript, edited the manuscript and provided ideas, conceived proteomics experiments, collected worms for proteomics experiments and performed two of the starvation experiments, compiled the protein reference database, did statistical analyses and processed and analyzed the proteomics data	conceived the study and the manuscript, edited the manuscript and provided ideas, conceived proteomics experiments, collected worms for proteomics experiments and performed two of the starvation experiments, compiled the protein reference database, did statistical analyses and processed and analyzed the proteomics data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Data curation|Formal analysis|Investigation|Resources|Software|Writing - Review & Editing	YES
5117596	27871231	ND	2	was involved in the organization and coordination of this study, provided ideas and commented on the manuscript	was involved in the organization and coordination of this study, provided ideas and commented on the manuscript	Conceived and designed the experiments	Conceptualization|Project administration	YES
5117596	27871231	PEA	2	processed proteomics data and commented on the manuscript	processed proteomics data and commented on the manuscript	Analyzed the data	Data curation	YES
5117596	27871231	RJG	2	processed proteomics data and commented on the manuscript	processed proteomics data and commented on the manuscript	Analyzed the data	Data curation	YES
3046910	21314914	AB	2	contributed to the study concept, and the writing of the project proposal and the paper	contributed to the study concept, and the writing of the project proposal and the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
3046910	21314914	EF	2	was responsible for the clinical aspects of the study|identified the patients, abstracted the clinical information and recruited the patients in the study	was responsible for the clinical aspects of the study	-	-	NO
3046910	21314914	EF	2	was responsible for the clinical aspects of the study|identified the patients, abstracted the clinical information and recruited the patients in the study	identified the patients, abstracted the clinical information and recruited the patients in the study	Performed the experiments	Investigation	YES
3046910	21314914	ELISAs	2	for immune activation, contributed to the study design, data analysis and interpretation of the data	for immune activation, contributed to the study design, data analysis and interpretation of the data	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Methodology|Resources	YES
3046910	21314914	GV	2	supervisor and principal investigator of the project, contributed to the study design, data analysis and interpretation of the data	supervisor and principal investigator of the project, contributed to the study design, data analysis and interpretation of the data	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Funding acquisition|Methodology|Resources|Supervision	YES
3046910	21314914	LH	2	was responsible for the molecular biological aspects of this study and performed all sequence analyses	was responsible for the molecular biological aspects of this study and performed all sequence analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3046910	21314914	PL	2	performed all the statistical data analyses	performed all the statistical data analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3046910	21314914	SC	2	performed all dna isolations and amplifications	performed all dna isolations and amplifications	Performed the experiments	Investigation	YES
4401688	25885258	AL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401688	25885258	AL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4401688	25885258	AL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401688	25885258	HH	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401688	25885258	MD	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401688	25885258	MFL	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401688	25885258	MG	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401688	25885258	MR	PLoS5	Analyzed the data|Wrote the paper|Literature research	Analyzed the data	Analyzed the data	Formal analysis	YES
4401688	25885258	MR	PLoS5	Analyzed the data|Wrote the paper|Literature research	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401688	25885258	MR	PLoS5	Analyzed the data|Wrote the paper|Literature research	Literature research	-	Formal analysis	YES
4401688	25885258	UWEP	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401688	25885258	UWEP	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4492750	26236482	Lamm Bergstrom	5	was responsible for modeling and simulation of the pk-pd data and Tunek for the pk evaluations	was responsible for modeling and simulation of the pk-pd data and Tunek for the pk evaluations	Performed the experiments	Formal analysis|Methodology	YES
5479923	28690631	SF	PLoS52	designed the experiment|analyzed the data|wrote the manuscript	designed the experiment	Conceived and designed the experiments	Methodology	YES
5479923	28690631	SF	PLoS52	designed the experiment|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5479923	28690631	SF	PLoS52	designed the experiment|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5479923	28690631	YF	PLoS52	carried out the experiment|analyzed the data|wrote the manuscript	carried out the experiment	Performed the experiments	Investigation	YES
5479923	28690631	YF	PLoS52	carried out the experiment|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5479923	28690631	YF	PLoS52	carried out the experiment|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5479923	28690631	YY	PLoS52	analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5479923	28690631	YY	PLoS52	analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3049128	21314993	AT	2	assissted in concept and design aspects and directed sample- and data acquisition	assissted in concept and design aspects and directed sample- and data acquisition	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Supervision	YES
3049128	21314993	FW	2	has made substantive intellectual contribution to the study including acquisition-, analysis- and interpretation of data and finally drafting the manuscript	has made substantive intellectual contribution to the study including acquisition-, analysis- and interpretation of data and finally drafting the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft	YES
3049128	21314993	GN	2	was responsible with genotyping processes as described in the manuscript	was responsible with genotyping processes as described in the manuscript	Performed the experiments	Investigation	YES
3049128	21314993	HK	2	were significantly involved in data acquisition, provision of samples and manuscript revision	were significantly involved in data acquisition, provision of samples and manuscript revision	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
3049128	21314993	HW	2	realized the phenotypic resistance analysis	realized the phenotypic resistance analysis	Performed the experiments	Investigation	YES
3049128	21314993	JV	2	assisted as consultant in patient-specific aspects and was involved in manuscript revision	assisted as consultant in patient-specific aspects and was involved in manuscript revision	Wrote the paper	Writing - Review & Editing	YES
3049128	21314993	MS	2	were significantly involved in data acquisition, provision of samples and manuscript revision	were significantly involved in data acquisition, provision of samples and manuscript revision	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
3049128	21314993	PB	2	assissted in concept and design aspects and directed sample- and data acquisition	assissted in concept and design aspects and directed sample- and data acquisition	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Supervision	YES
3049128	21314993	RE	2	was responsible for genotypic resistance interpretation and manuscript revision	was responsible for genotypic resistance interpretation and manuscript revision	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
3049128	21314993	RK	2	were significantly involved in data acquisition, provision of samples and manuscript revision	were significantly involved in data acquisition, provision of samples and manuscript revision	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
3049128	21314993	TB	2	were significantly involved in data acquisition, provision of samples and manuscript revision	were significantly involved in data acquisition, provision of samples and manuscript revision	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5608794	28550485	Chunqing Xie	2	conducted the treatment	conducted the treatment	Performed the experiments	Investigation	YES
5608794	28550485	Guifang Wan	2	supervised the recruitment and interventions for participants	supervised the recruitment and interventions for participants	Performed the experiments	Investigation|Supervision	YES
5608794	28550485	VFSS	2	advised on the preparation of the manuscript	advised on the preparation of the manuscript	Wrote the paper	Writing - Original Draft	YES
5608794	28550485	Xiaomei Wei	2	coordinated the project, conceptualized and conducted studies, recruited patients, wrote the manuscript, and analyzed mep data	coordinated the project, conceptualized and conducted studies, recruited patients, wrote the manuscript, and analyzed mep data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Project administration|Writing - Original Draft	YES
5608794	28550485	Yujue Wang	2	coordinated the project and helped to do data analysis	coordinated the project and helped to do data analysis	Analyzed the data	Formal analysis|Project administration	YES
5608794	28550485	Zulin Dou	2	directed the project, wrote original grant applications, supervised training and conduct of studies, and supervised the preparation of manuscript	directed the project, wrote original grant applications, supervised training and conduct of studies, and supervised the preparation of manuscript	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Original Draft	YES
4837960	27018719	All authors	2	have given approval to the final version of the manuscript	have given approval to the final version of the manuscript	-	-	NO
4401689	25884484	AWS	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401689	25884484	BA	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401689	25884484	BA	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401689	25884484	CSL	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401689	25884484	CSL	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401689	25884484	CWH	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401689	25884484	DMR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401689	25884484	DMR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401689	25884484	DMR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401689	25884484	DMR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401689	25884484	EM	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401689	25884484	EM	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401689	25884484	JCG	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401689	25884484	JCG	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401689	25884484	JPC	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401689	25884484	JPC	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401689	25884484	MSO	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401689	25884484	MSO	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401689	25884484	MSO	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5117602	27871240	AGC	2	supervised the study	supervised the study	-	Supervision	YES
5117602	27871240	ERD	2	performed the analysis|prepared the manuscript, with comments from all authors	performed the analysis	Performed the experiments	Investigation	YES
5117602	27871240	ERD	2	performed the analysis|prepared the manuscript, with comments from all authors	prepared the manuscript, with comments from all authors	Wrote the paper	Writing - Original Draft	YES
5117602	27871240	JKG	2	oversaw microbial data generation|performed the analysis	oversaw microbial data generation	Performed the experiments	Investigation|Supervision	YES
5117602	27871240	JKG	2	oversaw microbial data generation|performed the analysis	performed the analysis	Performed the experiments	Investigation	YES
5117602	27871240	JTB	2	oversaw the collection of samples and phenotype data	oversaw the collection of samples and phenotype data	Performed the experiments	Investigation|Supervision	YES
5117602	27871240	REL	2	supervised the study|oversaw microbial data generation	supervised the study	-	Supervision	YES
5117602	27871240	REL	2	supervised the study|oversaw microbial data generation	oversaw microbial data generation	Performed the experiments	Investigation|Supervision	YES
5117602	27871240	TDS	2	oversaw the collection of samples and phenotype data	oversaw the collection of samples and phenotype data	Performed the experiments	Investigation|Supervision	YES
5479926	28690621	BR	2	analyzed data and wrote the paper	analyzed data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5479926	28690621	MM	2	designed the experiments|conducted the experiment|analyzed data and wrote the paper	designed the experiments	Conceived and designed the experiments	Methodology	YES
5479926	28690621	MM	2	designed the experiments|conducted the experiment|analyzed data and wrote the paper	conducted the experiment	Performed the experiments	Investigation	YES
5479926	28690621	MM	2	designed the experiments|conducted the experiment|analyzed data and wrote the paper	analyzed data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5479926	28690621	OG	2	designed the experiments|conducted the experiment|analyzed data and wrote the paper	designed the experiments	Conceived and designed the experiments	Methodology	YES
5479926	28690621	OG	2	designed the experiments|conducted the experiment|analyzed data and wrote the paper	conducted the experiment	Performed the experiments	Investigation	YES
5479926	28690621	OG	2	designed the experiments|conducted the experiment|analyzed data and wrote the paper	analyzed data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5479926	28690621	ZP	2	designed the experiments|analyzed data and wrote the paper	designed the experiments	Conceived and designed the experiments	Methodology	YES
5479926	28690621	ZP	2	designed the experiments|analyzed data and wrote the paper	analyzed data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3058008	21371301	CS	2	carried out the interviews, conceived the study and drafted the first manuscript	carried out the interviews, conceived the study and drafted the first manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
3058008	21371301	MFC	2	assisted in drafting the manuscript and gave critical review	assisted in drafting the manuscript and gave critical review	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3058008	21371301	VB	2	participated in study conception, design, execution, coordination and helped to draft the manuscript	participated in study conception, design, execution, coordination and helped to draft the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Project administration|Writing - Original Draft	YES
4401690	25884637	JS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401690	25884637	JS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401690	25884637	JS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401690	25884637	KM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401690	25884637	KM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401690	25884637	KM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401690	25884637	KM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401690	25884637	MD	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401690	25884637	MD	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401690	25884637	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401690	25884637	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401690	25884637	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401690	25884637	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401690	25884637	RK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401690	25884637	RK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401690	25884637	RK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401690	25884637	RK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401690	25884637	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401690	25884637	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401690	25884637	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401690	25884637	VAH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401690	25884637	VAH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401690	25884637	VAH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401690	25884637	VAH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4492759	26236485	AA	2	performed and analyzed the data from the conscious animal studies	performed and analyzed the data from the conscious animal studies	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4492759	26236485	AL	2	performed and analyzed the data from the conscious animal studies	performed and analyzed the data from the conscious animal studies	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4492759	26236485	All authors	2	contributed to the drafting of the manuscript	contributed to the drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
4492759	26236485	ER	2	performed and analyzed the data from the conscious animal studies	performed and analyzed the data from the conscious animal studies	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4492759	26236485	SH	2	performed and analyzed the data from the conscious animal studies	performed and analyzed the data from the conscious animal studies	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5479929	28690629	DN	PLoS52	contributed to germplasm collection	contributed to germplasm collection	-	-	NO
5479929	28690629	HK	PLoS52	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5479929	28690629	JP	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5479929	28690629	JiC	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5479929	28690629	JuC	PLoS52	conceived and designed the experiments|performed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5479929	28690629	JuC	PLoS52	conceived and designed the experiments|performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5479929	28690629	KH	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5479929	28690629	ND	PLoS52	contributed to germplasm collection	contributed to germplasm collection	-	-	NO
5479929	28690629	QZ	PLoS52	contributed to germplasm collection	contributed to germplasm collection	-	-	NO
5479929	28690629	WH	PLoS52	performed the bioinformatics analyses	performed the bioinformatics analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5479929	28690629	YH	PLoS52	performed the bioinformatics analyses	performed the bioinformatics analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5117610	27871244	All authors	2	edited the draft, and read and approved the final manuscript	edited the draft, and read and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5117610	27871244	ERS	2	performed data analysis and further laboratory work|wrote the initial draft manuscript	performed data analysis and further laboratory work	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5117610	27871244	ERS	2	performed data analysis and further laboratory work|wrote the initial draft manuscript	wrote the initial draft manuscript	Wrote the paper	Writing - Original Draft	YES
5117610	27871244	HWC	2	were responsible for the initial design and co-ordination of the study	were responsible for the initial design and co-ordination of the study	Conceived and designed the experiments	Methodology|Project administration	YES
5117610	27871244	LA	2	were responsible for the initial design and co-ordination of the study	were responsible for the initial design and co-ordination of the study	Conceived and designed the experiments	Methodology|Project administration	YES
5117610	27871244	RNA	2	library preparations for sequencing	library preparations for sequencing	Performed the experiments	Investigation	YES
5117610	27871244	SMS	2	assisted with data analysis	assisted with data analysis	Analyzed the data	Formal analysis	YES
3058009	21356115	AD	2	conceived the study designed the study, analyzed the data and wrote the first draft	conceived the study designed the study, analyzed the data and wrote the first draft	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
3058009	21356115	All authors	2	contributed to the manuscript and approved its final version	contributed to the manuscript and approved its final version	-	-	NO
3058009	21356115	KD	2	analyzed the data and contributed to the draft manuscript	analyzed the data and contributed to the draft manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3058009	21356115	YA	2	conceived the study designed the study, analyzed the data and wrote the first draft	conceived the study designed the study, analyzed the data and wrote the first draft	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
4401691	25885345	AD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Final approval of the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401691	25885345	AD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Final approval of the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4401691	25885345	AD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Final approval of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4401691	25885345	AD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Final approval of the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401691	25885345	AD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Final approval of the manuscript	Final approval of the manuscript	-	-	NO
4401691	25885345	AdW	PLoS5	Performed the experiments|Analyzed the data|Revised the manuscript critically for important intellectual content|Final approval of the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4401691	25885345	AdW	PLoS5	Performed the experiments|Analyzed the data|Revised the manuscript critically for important intellectual content|Final approval of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4401691	25885345	AdW	PLoS5	Performed the experiments|Analyzed the data|Revised the manuscript critically for important intellectual content|Final approval of the manuscript	Revised the manuscript critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4401691	25885345	AdW	PLoS5	Performed the experiments|Analyzed the data|Revised the manuscript critically for important intellectual content|Final approval of the manuscript	Final approval of the manuscript	-	-	NO
4401691	25885345	BYDW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Final approval of the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401691	25885345	BYDW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Final approval of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4401691	25885345	BYDW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Final approval of the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401691	25885345	BYDW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Final approval of the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401691	25885345	BYDW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Final approval of the manuscript	Final approval of the manuscript	-	-	NO
4401691	25885345	HC	PLoS5	Performed the experiments|Analyzed the data|Revised the manuscript critically for important intellectual content|Final approval of the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4401691	25885345	HC	PLoS5	Performed the experiments|Analyzed the data|Revised the manuscript critically for important intellectual content|Final approval of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4401691	25885345	HC	PLoS5	Performed the experiments|Analyzed the data|Revised the manuscript critically for important intellectual content|Final approval of the manuscript	Revised the manuscript critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4401691	25885345	HC	PLoS5	Performed the experiments|Analyzed the data|Revised the manuscript critically for important intellectual content|Final approval of the manuscript	Final approval of the manuscript	-	-	NO
4401691	25885345	JGDM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Final approval of the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401691	25885345	JGDM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Final approval of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4401691	25885345	JGDM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Final approval of the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401691	25885345	JGDM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Final approval of the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401691	25885345	JGDM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Final approval of the manuscript	Final approval of the manuscript	-	-	NO
4401691	25885345	JPT	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Revised the manuscript critically for important intellectual content|Final approval of the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4401691	25885345	JPT	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Revised the manuscript critically for important intellectual content|Final approval of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4401691	25885345	JPT	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Revised the manuscript critically for important intellectual content|Final approval of the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401691	25885345	JPT	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Revised the manuscript critically for important intellectual content|Final approval of the manuscript	Revised the manuscript critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4401691	25885345	JPT	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Revised the manuscript critically for important intellectual content|Final approval of the manuscript	Final approval of the manuscript	-	-	NO
4401691	25885345	LdvL	PLoS5	Revised the manuscript critically for important intellectual content	Revised the manuscript critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4401691	25885345	LvdL	PLoS5	Performed the experiments|Analyzed the data|Final approval of the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4401691	25885345	LvdL	PLoS5	Performed the experiments|Analyzed the data|Final approval of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4401691	25885345	LvdL	PLoS5	Performed the experiments|Analyzed the data|Final approval of the manuscript	Final approval of the manuscript	-	-	NO
4401691	25885345	PAP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Revised the manuscript critically for important intellectual content|Final approval of the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401691	25885345	PAP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Revised the manuscript critically for important intellectual content|Final approval of the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401691	25885345	PAP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Revised the manuscript critically for important intellectual content|Final approval of the manuscript	Revised the manuscript critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4401691	25885345	PAP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Revised the manuscript critically for important intellectual content|Final approval of the manuscript	Final approval of the manuscript	-	-	NO
4401691	25885345	RB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Final approval of the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4401691	25885345	RB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Final approval of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4401691	25885345	RB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Final approval of the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401691	25885345	RB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Final approval of the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401691	25885345	RB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Final approval of the manuscript	Final approval of the manuscript	-	-	NO
4401691	25885345	TGM	PLoS5	Conceived and designed the experiments|Revised the manuscript critically for important intellectual content|Final approval of the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401691	25885345	TGM	PLoS5	Conceived and designed the experiments|Revised the manuscript critically for important intellectual content|Final approval of the manuscript	Revised the manuscript critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4401691	25885345	TGM	PLoS5	Conceived and designed the experiments|Revised the manuscript critically for important intellectual content|Final approval of the manuscript	Final approval of the manuscript	-	-	NO
4916484	27257848	All authors	2	have given approval to the final version of the manuscript	have given approval to the final version of the manuscript	-	-	NO
5117616	27871225	AN	PLoS5	Conducted the experiments|Analyzed the data	Conducted the experiments	Performed the experiments	Investigation	YES
5117616	27871225	AN	PLoS5	Conducted the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5117616	27871225	BM	PLoS5	Conceived and designed the experiments|Wrote the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5117616	27871225	BM	PLoS5	Conceived and designed the experiments|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5117616	27871225	BNK	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5117616	27871225	JRW	PLoS5	Conducted the experiments	Conducted the experiments	Performed the experiments	Investigation	YES
5117616	27871225	PJB	PLoS5	Conducted the experiments	Conducted the experiments	Performed the experiments	Investigation	YES
5117616	27871225	PJP	PLoS5	Conceived and designed the experiments|Wrote the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5117616	27871225	PJP	PLoS5	Conceived and designed the experiments|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5117616	27871225	SOK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5117616	27871225	SOK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
5117616	27871225	SOK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5117616	27871225	TSB	PLoS5	Analyzed the data|Wrote the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
5117616	27871225	TSB	PLoS5	Analyzed the data|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5479930	28690624	JB	2	conceived and designed the study|revised the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5479930	28690624	JB	2	conceived and designed the study|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5479930	28690624	JH	2	did the qpcr analysis experiments in hrs and developmental series|revised the manuscript	did the qpcr analysis experiments in hrs and developmental series	Performed the experiments	Investigation	YES
5479930	28690624	JH	2	did the qpcr analysis experiments in hrs and developmental series|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5479930	28690624	UV-B	2	greenhouse and field experiments	greenhouse and field experiments	Performed the experiments	Investigation	YES
4401692	25886290	MAG	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401692	25886290	MAG	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401692	25886290	MAG	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401692	25886290	MAG	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401692	25886290	MS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4401692	25886290	MS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401692	25886290	PKM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401692	25886290	PKM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401692	25886290	PKM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401692	25886290	PKM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401692	25886290	PMG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401692	25886290	PMG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401692	25886290	PMG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401692	25886290	PMG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401692	25886290	PMG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401692	25886290	REB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401692	25886290	REB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401692	25886290	REB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401692	25886290	REB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3060857	21375746	AO	7	Prepared the discussion section	Prepared the discussion section	-	-	NO
3060857	21375746	DU	7	prepared the background section	prepared the background section	-	-	NO
3060857	21375746	PN	7	Prepared the discussion section	Prepared the discussion section	-	-	NO
3060857	21375746	RO	7	Participated in the inception of the idea of this manuscript, with lead roles in conducting literature review, data analysis, writing the results and discussion sections	Participated in the inception of the idea of this manuscript, with lead roles in conducting literature review, data analysis, writing the results and discussion sections	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
3060857	21375746	SK	7	prepared the background section	prepared the background section	-	-	NO
5117676	27871234	BD	2	constructed and characterized bac library	constructed and characterized bac library	Performed the experiments	Investigation	YES
5117676	27871234	HZ	2	designed the experiments|constructed and characterized bac library|analyzed bess|analyzed data|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5117676	27871234	HZ	2	designed the experiments|constructed and characterized bac library|analyzed bess|analyzed data|wrote the manuscript	constructed and characterized bac library	Performed the experiments	Investigation	YES
5117676	27871234	HZ	2	designed the experiments|constructed and characterized bac library|analyzed bess|analyzed data|wrote the manuscript	analyzed bess	Analyzed the data	Formal analysis	YES
5117676	27871234	HZ	2	designed the experiments|constructed and characterized bac library|analyzed bess|analyzed data|wrote the manuscript	analyzed data	Analyzed the data	Formal analysis	YES
5117676	27871234	HZ	2	designed the experiments|constructed and characterized bac library|analyzed bess|analyzed data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5117676	27871234	JH	2	analyzed bess	analyzed bess	Analyzed the data	Formal analysis	YES
5117676	27871234	QL	2	designed the experiments|analyzed data|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5117676	27871234	QL	2	designed the experiments|analyzed data|wrote the manuscript	analyzed data	Analyzed the data	Formal analysis	YES
5117676	27871234	QL	2	designed the experiments|analyzed data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5117676	27871234	SH	2	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5117676	27871234	ZS	2	designed the experiments|constructed and characterized bac library|analyzed bess|analyzed data|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5117676	27871234	ZS	2	designed the experiments|constructed and characterized bac library|analyzed bess|analyzed data|wrote the manuscript	constructed and characterized bac library	Performed the experiments	Investigation	YES
5117676	27871234	ZS	2	designed the experiments|constructed and characterized bac library|analyzed bess|analyzed data|wrote the manuscript	analyzed bess	Analyzed the data	Formal analysis	YES
5117676	27871234	ZS	2	designed the experiments|constructed and characterized bac library|analyzed bess|analyzed data|wrote the manuscript	analyzed data	Analyzed the data	Formal analysis	YES
5117676	27871234	ZS	2	designed the experiments|constructed and characterized bac library|analyzed bess|analyzed data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4401694	25885796	ARV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401694	25885796	ARV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401694	25885796	ARV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401694	25885796	ARV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401694	25885796	CWG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Critically reviewed the submitted version of the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401694	25885796	CWG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Critically reviewed the submitted version of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4401694	25885796	CWG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Critically reviewed the submitted version of the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401694	25885796	CWG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Critically reviewed the submitted version of the manuscript	Critically reviewed the submitted version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4401694	25885796	HX	PLoS5	Performed the experiments|Analyzed the data|Critically reviewed the submitted version of the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4401694	25885796	HX	PLoS5	Performed the experiments|Analyzed the data|Critically reviewed the submitted version of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4401694	25885796	HX	PLoS5	Performed the experiments|Analyzed the data|Critically reviewed the submitted version of the manuscript	Critically reviewed the submitted version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4401694	25885796	KD	PLoS5	Performed the experiments|Analyzed the data|Critically reviewed the submitted version of the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4401694	25885796	KD	PLoS5	Performed the experiments|Analyzed the data|Critically reviewed the submitted version of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4401694	25885796	KD	PLoS5	Performed the experiments|Analyzed the data|Critically reviewed the submitted version of the manuscript	Critically reviewed the submitted version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4401694	25885796	YL	PLoS5	Performed the experiments|Analyzed the data|Critically reviewed the submitted version of the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4401694	25885796	YL	PLoS5	Performed the experiments|Analyzed the data|Critically reviewed the submitted version of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4401694	25885796	YL	PLoS5	Performed the experiments|Analyzed the data|Critically reviewed the submitted version of the manuscript	Critically reviewed the submitted version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5480015	28690616	CL	2	provided sweet potato varieties for the study and helped with plant management	provided sweet potato varieties for the study and helped with plant management	Performed the experiments	Investigation	YES
5480015	28690616	DT	2	assisted with field manipulation and plant management	assisted with field manipulation and plant management	Performed the experiments	Investigation	YES
5480015	28690616	HL	2	contributed to sr collection, trait measurement, and sample preparation	contributed to sr collection, trait measurement, and sample preparation	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5480015	28690616	JD	2	performed data analysis	performed data analysis	Analyzed the data	Formal analysis	YES
5480015	28690616	JW	2	provided sweet potato varieties for the study and helped with plant management	provided sweet potato varieties for the study and helped with plant management	Performed the experiments	Investigation	YES
5480015	28690616	KLu	2	performed data analysis	performed data analysis	Analyzed the data	Formal analysis	YES
5480015	28690616	KLuo	2	contributed to sr collection, trait measurement, and sample preparation	contributed to sr collection, trait measurement, and sample preparation	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5480015	28690616	KZ	2	wrote the paper, designed and led much of the experimental work, and carried out the transcriptome analysis	wrote the paper, designed and led much of the experimental work, and carried out the transcriptome analysis	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5480015	28690616	XW	2	contributed to sr collection, trait measurement, and sample preparation	contributed to sr collection, trait measurement, and sample preparation	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5480015	28690616	YL	2	contributed to sr collection, trait measurement, and sample preparation	contributed to sr collection, trait measurement, and sample preparation	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5480015	28690616	ZW	2	carried out much of the experimental work, performed trait measurements and qrt-pcr detection	carried out much of the experimental work, performed trait measurements and qrt-pcr detection	Performed the experiments	Investigation	YES
3061893	21385339	CD	2	conducted the colorectal explant experiments	conducted the colorectal explant experiments	Performed the experiments	Investigation	YES
3061893	21385339	LCR	2	served as principle investigator for the mdp program formulation core, guided and participated in study conception, design, data analysis and drafting of the manuscript	served as principle investigator for the mdp program formulation core, guided and participated in study conception, design, data analysis and drafting of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Supervision|Writing - Original Draft	YES
3061893	21385339	LW	2	carried out all the formulation compounding, testing and laboratory analysis, wrote reports and drafted the manuscript	carried out all the formulation compounding, testing and laboratory analysis, wrote reports and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
3061893	21385339	MDP	2	program principle investigator, oversaw project progress and reviewed and commented on the manuscript	program principle investigator, oversaw project progress and reviewed and commented on the manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
3061893	21385339	RLS	2	participated in project design, performed data and statistical analysis and helped draft the manuscript	participated in project design, performed data and statistical analysis and helped draft the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3063201	21385370	AA	2	conceived the study design, contributed to the demographic modeling methods, and wrote the first draft of the manuscript	conceived the study design, contributed to the demographic modeling methods, and wrote the first draft of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
3063201	21385370	AK	2	contributed to specialized knowledge on reproductive health issues specific countries under investigation	contributed to specialized knowledge on reproductive health issues specific countries under investigation	Performed the experiments	Investigation	YES
3063201	21385370	BRSH	2	provided critical feedback on study design and manuscript draft	provided critical feedback on study design and manuscript draft	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3063201	21385370	CA	2	ran the demographic projection software and contributed to the first draft of the paper	ran the demographic projection software and contributed to the first draft of the paper	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Software|Writing - Original Draft	YES
3063201	21385370	JSGM	2	provided critical feedback on study design and manuscript draft	provided critical feedback on study design and manuscript draft	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3063201	21385370	KV	2	provided critical feedback on study design and manuscript draft	provided critical feedback on study design and manuscript draft	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3063201	21385370	MJ	2	ran the demographic projection software and contributed to the first draft of the paper	ran the demographic projection software and contributed to the first draft of the paper	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Software|Writing - Original Draft	YES
3063201	21385370	SK	2	provided critical feedback on study design and manuscript draft	provided critical feedback on study design and manuscript draft	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5480306	28690618	DB	PLoS52	conceived and planned the work|analyzed the data|drafted the manuscript	conceived and planned the work	Conceived and designed the experiments	Conceptualization	YES
5480306	28690618	DB	PLoS52	conceived and planned the work|analyzed the data|drafted the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5480306	28690618	DB	PLoS52	conceived and planned the work|analyzed the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5480306	28690618	KA	PLoS52	performed phenotypic and genotypic screening	performed phenotypic and genotypic screening	Performed the experiments	Investigation	YES
5480306	28690618	MS	PLoS52	performed phenotypic and genotypic screening|analyzed the data|drafted the manuscript	performed phenotypic and genotypic screening	Performed the experiments	Investigation	YES
5480306	28690618	MS	PLoS52	performed phenotypic and genotypic screening|analyzed the data|drafted the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5480306	28690618	MS	PLoS52	performed phenotypic and genotypic screening|analyzed the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5480306	28690618	SM	PLoS52	performed phenotypic and genotypic screening	performed phenotypic and genotypic screening	Performed the experiments	Investigation	YES
5480306	28690618	SN	PLoS52	conceived and planned the work|drafted the manuscript	conceived and planned the work	Conceived and designed the experiments	Conceptualization	YES
5480306	28690618	SN	PLoS52	conceived and planned the work|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5480306	28690618	TV	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5480306	28690618	VY	PLoS52	performed phenotypic and genotypic screening	performed phenotypic and genotypic screening	Performed the experiments	Investigation	YES
5118885	27875983	CJS	2	participated in the design of the study and acquisition of funding	participated in the design of the study and acquisition of funding	Conceived and designed the experiments	Funding acquisition|Methodology	YES
5118885	27875983	JCH	2	participated in the analysis of the data and the drafting of the manuscript	participated in the analysis of the data and the drafting of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5118885	27875983	QZ	2	participated in the drafting of the manuscript	participated in the drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
5118885	27875983	SJL	2	participated in the design of the study, sample collection, acquisition of funding and helped to draft the manuscript	participated in the design of the study, sample collection, acquisition of funding and helped to draft the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Funding acquisition|Investigation|Methodology|Writing - Original Draft	YES
5118885	27875983	XL	2	performed the experiments, analyzed the data and drafted the manuscript	performed the experiments, analyzed the data and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4401695	25886645	AR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401695	25886645	AR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401695	25886645	AR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401695	25886645	AR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401695	25886645	AR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401695	25886645	BF	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4401695	25886645	BF	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401695	25886645	BWJ	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401695	25886645	CM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401695	25886645	EL	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401695	25886645	EL	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401695	25886645	JSR	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4401695	25886645	JSR	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401695	25886645	KPB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401695	25886645	LT	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401695	25886645	MJG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401695	25886645	MJG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401695	25886645	MJG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401695	25886645	MW	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4401695	25886645	MW	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401695	25886645	NKB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401695	25886645	PL	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401695	25886645	RS	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401695	25886645	SEG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4401695	25886645	SEG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401695	25886645	SN	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401695	25886645	SN	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401695	25886645	SN	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401695	25886645	SN	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401695	25886645	TS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401695	25886645	TS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4492765	26171228	J. Foucquier	2	performed bibliographic review and wrote the paper	performed bibliographic review and wrote the paper	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
4492765	26171228	M. Guedj	2	performed bibliographic review and wrote the paper	performed bibliographic review and wrote the paper	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
3065397	21388558	CS	2	conceived and designed the study|drafted the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3065397	21388558	CS	2	conceived and designed the study|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
3065397	21388558	EL	2	conceived and designed the study|provided critical revisions of the article for important intellectual content	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3065397	21388558	EL	2	conceived and designed the study|provided critical revisions of the article for important intellectual content	provided critical revisions of the article for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
3065397	21388558	JC	2	conceived and designed the study|drafted the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3065397	21388558	JC	2	conceived and designed the study|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
3065397	21388558	KF	2	provided critical revisions of the article for important intellectual content	provided critical revisions of the article for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
3065397	21388558	YY	2	provided critical revisions of the article for important intellectual content	provided critical revisions of the article for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5481357	28690619	CA	PLoS52	contributed in the design of some experiments	contributed in the design of some experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5481357	28690619	FMC	PLoS52	designed the experiments|analyzed the data and wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5481357	28690619	FMC	PLoS52	designed the experiments|analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5481357	28690619	FRC	PLoS52	designed the experiments|analyzed the data and wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5481357	28690619	FRC	PLoS52	designed the experiments|analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5481357	28690619	FdT	PLoS52	contributed in the design of some experiments|performed the experiments	contributed in the design of some experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5481357	28690619	FdT	PLoS52	contributed in the design of some experiments|performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5481357	28690619	RC	PLoS52	contributed in the design of some experiments	contributed in the design of some experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5481357	28690619	SVK	PLoS52	performed the experiments|analyzed the data and wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5481357	28690619	SVK	PLoS52	performed the experiments|analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3073867	21435275	HW	2	supervised and coordinated the study	supervised and coordinated the study	-	Project administration|Supervision	YES
3073867	21435275	HZ	2	conceived the study and participated in the data analysis	conceived the study and participated in the data analysis	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
3073867	21435275	TZ	2	followed up patients and collected samples	followed up patients and collected samples	Performed the experiments	Investigation	YES
3073867	21435275	WH	2	participated in flow cytometric analysis	participated in flow cytometric analysis	Performed the experiments	Investigation	YES
3073867	21435275	YJ	2	drafted the manuscript and statistical analyses|assisted with flow cytometric analysis and data acquisition	drafted the manuscript and statistical analyses	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3073867	21435275	YJ	2	drafted the manuscript and statistical analyses|assisted with flow cytometric analysis and data acquisition	assisted with flow cytometric analysis and data acquisition	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3073867	21435275	YZ	2	assisted with manuscript and data anlysis	assisted with manuscript and data anlysis	-	-	NO
5118889	27875982	AA	2	sequenced and assembled the 13-13 genome and transcriptome and made these data available	sequenced and assembled the 13-13 genome and transcriptome and made these data available	Performed the experiments	Investigation	YES
5118889	27875982	CW	2	carried out the bioinformatics analyses of secondary metabolism enzymes	carried out the bioinformatics analyses of secondary metabolism enzymes	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5118889	27875982	DP	2	carried out general lab work, inoculation experiments and phylogeny analyses and provided the rcsp gene expression data|participated in gene annotation and collected the nip2 gene data	carried out general lab work, inoculation experiments and phylogeny analyses and provided the rcsp gene expression data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5118889	27875982	DP	2	carried out general lab work, inoculation experiments and phylogeny analyses and provided the rcsp gene expression data|participated in gene annotation and collected the nip2 gene data	participated in gene annotation and collected the nip2 gene data	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5118889	27875982	ES	2	carried out the smurf- and mdm-based gene cluster analyses	carried out the smurf- and mdm-based gene cluster analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5118889	27875982	JG	2	generated and characterized the rcsp deletion mutants	generated and characterized the rcsp deletion mutants	Performed the experiments	Investigation	YES
5118889	27875982	JH	2	generated and characterized the rcsp deletion mutants	generated and characterized the rcsp deletion mutants	Performed the experiments	Investigation	YES
5118889	27875982	KA	2	sequenced and assembled the 13-13 genome and transcriptome and made these data available	sequenced and assembled the 13-13 genome and transcriptome and made these data available	Performed the experiments	Investigation	YES
5118889	27875982	KP	2	sequenced and assembled the 13-13 genome and transcriptome and made these data available	sequenced and assembled the 13-13 genome and transcriptome and made these data available	Performed the experiments	Investigation	YES
5118889	27875982	M. All	2	authors provided intellectual input, all principal investigators read and approved the manuscript	authors provided intellectual input, all principal investigators read and approved the manuscript	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
5118889	27875982	MF	2	performed the genome sequencing and assembly except for isolate 13-13	performed the genome sequencing and assembly except for isolate 13-13	Performed the experiments	Investigation	YES
5118889	27875982	MM	2	conducted the genome annotation and all large-scale genome analyses	conducted the genome annotation and all large-scale genome analyses	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5118889	27875982	MP	2	performed the genome sequencing and assembly except for isolate 13-13	performed the genome sequencing and assembly except for isolate 13-13	Performed the experiments	Investigation	YES
5118889	27875982	NW	2	generated and characterized the rcsp deletion mutants	generated and characterized the rcsp deletion mutants	Performed the experiments	Investigation	YES
5118889	27875982	SK	2	carried out general lab work, inoculation experiments and phylogeny analyses and provided the rcsp gene expression data|generated and characterized the rcsp deletion mutants	carried out general lab work, inoculation experiments and phylogeny analyses and provided the rcsp gene expression data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5118889	27875982	SK	2	carried out general lab work, inoculation experiments and phylogeny analyses and provided the rcsp gene expression data|generated and characterized the rcsp deletion mutants	generated and characterized the rcsp deletion mutants	Performed the experiments	Investigation	YES
5118889	27875982	ST	2	performed the genome sequencing and assembly except for isolate 13-13	performed the genome sequencing and assembly except for isolate 13-13	Performed the experiments	Investigation	YES
5118889	27875982	TW	2	carried out the smurf- and mdm-based gene cluster analyses	carried out the smurf- and mdm-based gene cluster analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5118889	27875982	UG	2	conducted the genome annotation and all large-scale genome analyses	conducted the genome annotation and all large-scale genome analyses	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5118889	27875982	WK	2	carried out the bioinformatics analyses of secondary metabolism enzymes	carried out the bioinformatics analyses of secondary metabolism enzymes	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3415154	22919313	H. R. Yu	2	have equal contribution to this paper	have equal contribution to this paper	-	-	NO
3415154	22919313	P. C. Hou	2	have equal contribution to this paper	have equal contribution to this paper	-	-	NO
3083326	21453452	AHB	7	Experimental design, data analysis, Interpretation of data, drafted manuscript	Experimental design, data analysis, Interpretation of data, drafted manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3083326	21453452	AKD	7	Case identifications, clinical Aspects of the study, drafted the manuscript	Case identifications, clinical Aspects of the study, drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3083326	21453452	SKJ	7	Experimental design, molecular biology experiments, DNA/rna isolations, Viral load, PCR, Interpretation of data, Sequence analysis	Experimental design, molecular biology experiments, DNA/rna isolations, Viral load, PCR, Interpretation of data, Sequence analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
4401696	25886489	AS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4401696	25886489	AS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401696	25886489	JH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401696	25886489	JH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401696	25886489	JH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401696	25886489	JH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401696	25886489	QW	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401696	25886489	QW	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401696	25886489	SR	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401696	25886489	TPU	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4401696	25886489	TPU	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401696	25886489	XC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401696	25886489	YH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401696	25886489	YH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401696	25886489	YH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401696	25886489	YH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5481364	28690622	CZ	2	collected the samples, analyzed the samples, and drafted the manuscript	collected the samples, analyzed the samples, and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5481364	28690622	JZ	2	analyzed the data and revised the manuscript	analyzed the data and revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5481364	28690622	JjH	2	collected the samples and analyzed the samples	collected the samples and analyzed the samples	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5481364	28690622	JlH	2	conceived and designed this work	conceived and designed this work	Conceived and designed the experiments	Conceptualization	YES
5481364	28690622	LZ	2	analyzed the data and revised the manuscript	analyzed the data and revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5481364	28690622	QJ	2	conceived and designed this work	conceived and designed this work	Conceived and designed the experiments	Conceptualization	YES
5481364	28690622	XC	2	made a contribution to design of the work and to draft the manuscript	made a contribution to design of the work and to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
4777244	27022465	A. J. Mogg	2	designed the research study|performed the research	designed the research study	Conceived and designed the experiments	Methodology	YES
4777244	27022465	A. J. Mogg	2	designed the research study|performed the research	performed the research	Performed the experiments	Investigation	YES
4777244	27022465	C. Gentry	2	performed the research	performed the research	Performed the experiments	Investigation	YES
4777244	27022465	L. M. Broad	2	designed the research study	designed the research study	Conceived and designed the experiments	Methodology	YES
4777244	27022465	S. Bevan	2	designed the research study	designed the research study	Conceived and designed the experiments	Methodology	YES
4777244	27022465	T. Quallo	2	designed the research study|performed the research|analyzed the data and wrote the paper	designed the research study	Conceived and designed the experiments	Methodology	YES
4777244	27022465	T. Quallo	2	designed the research study|performed the research|analyzed the data and wrote the paper	performed the research	Performed the experiments	Investigation	YES
4777244	27022465	T. Quallo	2	designed the research study|performed the research|analyzed the data and wrote the paper	analyzed the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5118896	27875986	LZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5118896	27875986	LZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
5118896	27875986	LZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5118896	27875986	LZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5118896	27875986	LZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5118896	27875986	MX	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
5118896	27875986	MX	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5118896	27875986	QS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5118896	27875986	XG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5118896	27875986	XG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5118896	27875986	XG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5118896	27875986	YL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
5118896	27875986	YL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
5118896	27875986	YL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
3117676	21569420	CSF	2	plasma neopterin	plasma neopterin	Performed the experiments	Investigation	YES
3117676	21569420	EL	2	served as the patient study coordinator, aided in the design of the study, performed the quantitative neurological performance testing and managed the data	served as the patient study coordinator, aided in the design of the study, performed the quantitative neurological performance testing and managed the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Data curation|Investigation|Methodology|Project administration	YES
3117676	21569420	ELH	2	examined study participants, performed lumbar punctures, and assisted with the analysis of the data and preparation of the manuscript	examined study participants, performed lumbar punctures, and assisted with the analysis of the data and preparation of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3117676	21569420	RWP	2	designed and oversaw the study, examined study participants, performed lumbar punctures, analysed and interpreted the data, and participated in preparation of the manuscript	designed and oversaw the study, examined study participants, performed lumbar punctures, analysed and interpreted the data, and participated in preparation of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Supervision|Writing - Original Draft	YES
3117676	21569420	SSS	2	examined study participants, performed lumbar punctures, and assisted in design of the study and reviewed the manuscript	examined study participants, performed lumbar punctures, and assisted in design of the study and reviewed the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
4401697	25886203	KO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401697	25886203	KO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401697	25886203	KO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401697	25886203	KO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401697	25886203	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401697	25886203	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401697	25886203	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401697	25886203	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401697	25886203	ST	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401697	25886203	TS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401697	25886203	TS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401697	25886203	TS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5120421	27881098	AJ	2	did the analysis and prepared the manuscript	did the analysis and prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5120421	27881098	AU	2	lead on analysis	lead on analysis	-	-	NO
5120421	27881098	BS	2	equally supervised the work and edited the manuscript	equally supervised the work and edited the manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
5120421	27881098	RB	2	prepared samples and manuscript	prepared samples and manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5120421	27881098	VC	2	equally supervised the work and edited the manuscript	equally supervised the work and edited the manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
4777245	27022466	AR	2	conducted experiments|contributed new reagents or analytic tools|wrote or contributed to the writing of the manuscript	conducted experiments	Performed the experiments	Investigation	YES
4777245	27022466	AR	2	conducted experiments|contributed new reagents or analytic tools|wrote or contributed to the writing of the manuscript	contributed new reagents or analytic tools	Contributed reagents/materials/analysis tools	Resources	YES
4777245	27022466	AR	2	conducted experiments|contributed new reagents or analytic tools|wrote or contributed to the writing of the manuscript	wrote or contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
4777245	27022466	EA	2	conducted experiments|wrote or contributed to the writing of the manuscript	conducted experiments	Performed the experiments	Investigation	YES
4777245	27022466	EA	2	conducted experiments|wrote or contributed to the writing of the manuscript	wrote or contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
4777245	27022466	HN	2	conducted experiments|contributed new reagents or analytic tools|wrote or contributed to the writing of the manuscript	conducted experiments	Performed the experiments	Investigation	YES
4777245	27022466	HN	2	conducted experiments|contributed new reagents or analytic tools|wrote or contributed to the writing of the manuscript	contributed new reagents or analytic tools	Contributed reagents/materials/analysis tools	Resources	YES
4777245	27022466	HN	2	conducted experiments|contributed new reagents or analytic tools|wrote or contributed to the writing of the manuscript	wrote or contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
4777245	27022466	IS	2	conducted experiments|contributed new reagents or analytic tools|wrote or contributed to the writing of the manuscript	conducted experiments	Performed the experiments	Investigation	YES
4777245	27022466	IS	2	conducted experiments|contributed new reagents or analytic tools|wrote or contributed to the writing of the manuscript	contributed new reagents or analytic tools	Contributed reagents/materials/analysis tools	Resources	YES
4777245	27022466	IS	2	conducted experiments|contributed new reagents or analytic tools|wrote or contributed to the writing of the manuscript	wrote or contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
4777245	27022466	LBB	2	participated in research design|performed data analysis|wrote or contributed to the writing of the manuscript	participated in research design	Conceived and designed the experiments	-	YES
4777245	27022466	LBB	2	participated in research design|performed data analysis|wrote or contributed to the writing of the manuscript	performed data analysis	Analyzed the data	Formal analysis	YES
4777245	27022466	LBB	2	participated in research design|performed data analysis|wrote or contributed to the writing of the manuscript	wrote or contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
4777245	27022466	LE	2	participated in research design|conducted experiments|contributed new reagents or analytic tools|performed data analysis|wrote or contributed to the writing of the manuscript	participated in research design	Conceived and designed the experiments	-	YES
4777245	27022466	LE	2	participated in research design|conducted experiments|contributed new reagents or analytic tools|performed data analysis|wrote or contributed to the writing of the manuscript	conducted experiments	Performed the experiments	Investigation	YES
4777245	27022466	LE	2	participated in research design|conducted experiments|contributed new reagents or analytic tools|performed data analysis|wrote or contributed to the writing of the manuscript	contributed new reagents or analytic tools	Contributed reagents/materials/analysis tools	Resources	YES
4777245	27022466	LE	2	participated in research design|conducted experiments|contributed new reagents or analytic tools|performed data analysis|wrote or contributed to the writing of the manuscript	performed data analysis	Analyzed the data	Formal analysis	YES
4777245	27022466	LE	2	participated in research design|conducted experiments|contributed new reagents or analytic tools|performed data analysis|wrote or contributed to the writing of the manuscript	wrote or contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
4777245	27022466	MLO	2	conducted experiments|contributed new reagents or analytic tools|wrote or contributed to the writing of the manuscript	conducted experiments	Performed the experiments	Investigation	YES
4777245	27022466	MLO	2	conducted experiments|contributed new reagents or analytic tools|wrote or contributed to the writing of the manuscript	contributed new reagents or analytic tools	Contributed reagents/materials/analysis tools	Resources	YES
4777245	27022466	MLO	2	conducted experiments|contributed new reagents or analytic tools|wrote or contributed to the writing of the manuscript	wrote or contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
4777245	27022466	UD	2	conducted experiments|contributed new reagents or analytic tools|wrote or contributed to the writing of the manuscript	conducted experiments	Performed the experiments	Investigation	YES
4777245	27022466	UD	2	conducted experiments|contributed new reagents or analytic tools|wrote or contributed to the writing of the manuscript	contributed new reagents or analytic tools	Contributed reagents/materials/analysis tools	Resources	YES
4777245	27022466	UD	2	conducted experiments|contributed new reagents or analytic tools|wrote or contributed to the writing of the manuscript	wrote or contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
3119192	21575228	All authors	2	participated in the design of the study and manuscript preparation	participated in the design of the study and manuscript preparation	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3119192	21575228	GAG	2	performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
5481370	28690628	All authors	PLoS52	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5481370	28690628	HZ	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5481370	28690628	LS	PLoS52	designed the research|wrote the paper	designed the research	Conceived and designed the experiments	Methodology	YES
5481370	28690628	LS	PLoS52	designed the research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5481370	28690628	ML	PLoS52	designed the research|performed the research|wrote the paper	designed the research	Conceived and designed the experiments	Methodology	YES
5481370	28690628	ML	PLoS52	designed the research|performed the research|wrote the paper	performed the research	Performed the experiments	Investigation	YES
5481370	28690628	ML	PLoS52	designed the research|performed the research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5481370	28690628	RG	PLoS52	designed the research|performed the research|wrote the paper	designed the research	Conceived and designed the experiments	Methodology	YES
5481370	28690628	RG	PLoS52	designed the research|performed the research|wrote the paper	performed the research	Performed the experiments	Investigation	YES
5481370	28690628	RG	PLoS52	designed the research|performed the research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5481370	28690628	The authors	PLoS52	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	Performed the experiments	Investigation	YES
5481370	28690628	XJ	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5481370	28690628	YJ	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401698	25885474	BCL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401698	25885474	BCL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401698	25885474	BCL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401698	25885474	DRD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401698	25885474	DRD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4401698	25885474	DRD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401698	25885474	DSK	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401698	25885474	DSK	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401698	25885474	LGA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401698	25885474	LGA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401698	25885474	LGA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401698	25885474	LGA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3123169	21631913	JA	2	gave scientific input and edited the manuscript	gave scientific input and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
3123169	21631913	NKL	2	reviewed the literature and drafted the manuscript	reviewed the literature and drafted the manuscript	Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
4259291	25506060	All authors	2	reviewed and revised the paper	reviewed and revised the paper	Wrote the paper	Writing - Review & Editing	YES
4259291	25506060	F.M.U.	2	directed this study, coordinated the research and wrote the final manuscript|have contributed to the design of the experiments and performed research	directed this study, coordinated the research and wrote the final manuscript	Wrote the paper	Project administration|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
4259291	25506060	F.M.U.	2	directed this study, coordinated the research and wrote the final manuscript|have contributed to the design of the experiments and performed research	have contributed to the design of the experiments and performed research	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4259291	25506060	H.M.	2	have contributed to the design of the experiments and performed research	have contributed to the design of the experiments and performed research	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4259291	25506060	J.Z.	2	have contributed to the design of the experiments and performed research|constructed the structural model for syk-cdc25c interactions	have contributed to the design of the experiments and performed research	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4259291	25506060	J.Z.	2	have contributed to the design of the experiments and performed research|constructed the structural model for syk-cdc25c interactions	constructed the structural model for syk-cdc25c interactions	Performed the experiments	Investigation|Methodology	YES
4259291	25506060	P.G.	2	have contributed to the design of the experiments and performed research	have contributed to the design of the experiments and performed research	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4259291	25506060	S.Q.	2	have contributed to the design of the experiments and performed research|performed the bioinformatics work and statistical analyses	have contributed to the design of the experiments and performed research	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4259291	25506060	S.Q.	2	have contributed to the design of the experiments and performed research|performed the bioinformatics work and statistical analyses	performed the bioinformatics work and statistical analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4259291	25506060	Z.O.	2	have contributed to the design of the experiments and performed research	have contributed to the design of the experiments and performed research	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5120471	27875993	CR-E	2	bioinformatics analysis of raw microarray data and bioinformatics guidance, critical review of the article	bioinformatics analysis of raw microarray data and bioinformatics guidance, critical review of the article	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Supervision|Writing - Review & Editing	YES
5120471	27875993	E. Conception	2	design, data analysis and interpretation, manuscript writing	design, data analysis and interpretation, manuscript writing	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5120471	27875993	II-R	2	bioinformatics analysis of raw microarray data and bioinformatics guidance, critical review of the article, manuscript writing	bioinformatics analysis of raw microarray data and bioinformatics guidance, critical review of the article, manuscript writing	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
5120471	27875993	JAV-P	2	guidance in pcr by high-throughput gene expression, critical review of the article	guidance in pcr by high-throughput gene expression, critical review of the article	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Review & Editing	YES
4401699	25884410	APG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401699	25884410	APG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401699	25884410	APG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401699	25884410	FM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401699	25884410	FM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401699	25884410	FM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401699	25884410	FM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401699	25884410	FM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401699	25884410	GL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401699	25884410	IAM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401699	25884410	IAM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401699	25884410	IAM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401699	25884410	IAM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401699	25884410	IAM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401699	25884410	LF	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401699	25884410	LF	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401699	25884410	LF	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401699	25884410	MM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4401699	25884410	MM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401699	25884410	NA	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4401699	25884410	NA	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401699	25884410	NF	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
3131237	21679427	BL	2	followed the elite controller subjects clinically and provided samples for this study	followed the elite controller subjects clinically and provided samples for this study	Contributed reagents/materials/analysis tools	Resources	YES
3131237	21679427	CC	2	followed the elite controller subjects clinically and provided samples for this study	followed the elite controller subjects clinically and provided samples for this study	Contributed reagents/materials/analysis tools	Resources	YES
3131237	21679427	CMS	2	followed the elite controller subjects clinically and provided samples for this study	followed the elite controller subjects clinically and provided samples for this study	Contributed reagents/materials/analysis tools	Resources	YES
3131237	21679427	CMT	2	aided in study design, and critical review of manuscript	aided in study design, and critical review of manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
3131237	21679427	CT	2	followed the elite controller subjects clinically and provided samples for this study	followed the elite controller subjects clinically and provided samples for this study	Contributed reagents/materials/analysis tools	Resources	YES
3131237	21679427	JPR	2	followed the elite controller subjects clinically and provided samples for this study	followed the elite controller subjects clinically and provided samples for this study	Contributed reagents/materials/analysis tools	Resources	YES
3131237	21679427	MO	2	followed the elite controller subjects clinically and provided samples for this study	followed the elite controller subjects clinically and provided samples for this study	Contributed reagents/materials/analysis tools	Resources	YES
3131237	21679427	MRB	2	followed the elite controller subjects clinically and provided samples for this study	followed the elite controller subjects clinically and provided samples for this study	Contributed reagents/materials/analysis tools	Resources	YES
3131237	21679427	NFB	2	designed the study and prepared manuscript	designed the study and prepared manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3131237	21679427	PC	2	followed the elite controller subjects clinically and provided samples for this study	followed the elite controller subjects clinically and provided samples for this study	Contributed reagents/materials/analysis tools	Resources	YES
3131237	21679427	PK	2	designed the study, designed and optimized the antibody panel, performed the experiments, analyzed the data and prepared the manuscript	designed the study, designed and optimized the antibody panel, performed the experiments, analyzed the data and prepared the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
3131237	21679427	RK	2	followed the elite controller subjects clinically and provided samples for this study	followed the elite controller subjects clinically and provided samples for this study	Contributed reagents/materials/analysis tools	Resources	YES
3131237	21679427	RT	2	followed the elite controller subjects clinically and provided samples for this study	followed the elite controller subjects clinically and provided samples for this study	Contributed reagents/materials/analysis tools	Resources	YES
3131237	21679427	SB	2	aided in study design, and critical review of manuscript	aided in study design, and critical review of manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5481406	28690620	DB	1	Contributed equally to this work|Contributions to the conception or design of the work|Drafting the work|Manuscript writing and critical review|Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Contributed equally to this work	-	-	NO
5481406	28690620	DB	1	Contributed equally to this work|Contributions to the conception or design of the work|Drafting the work|Manuscript writing and critical review|Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Contributions to the conception or design of the work	Conceived and designed the experiments	Conceptualization	YES
5481406	28690620	DB	1	Contributed equally to this work|Contributions to the conception or design of the work|Drafting the work|Manuscript writing and critical review|Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Drafting the work	Wrote the paper	Writing - Original Draft	YES
5481406	28690620	DB	1	Contributed equally to this work|Contributions to the conception or design of the work|Drafting the work|Manuscript writing and critical review|Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Manuscript writing and critical review	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5481406	28690620	DB	1	Contributed equally to this work|Contributions to the conception or design of the work|Drafting the work|Manuscript writing and critical review|Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	-	-	NO
5481406	28690620	GG	1	Contributions to the conception or design of the work|Drafting the work|Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Contributions to the conception or design of the work	Conceived and designed the experiments	Conceptualization	YES
5481406	28690620	GG	1	Contributions to the conception or design of the work|Drafting the work|Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Drafting the work	Wrote the paper	Writing - Original Draft	YES
5481406	28690620	GG	1	Contributions to the conception or design of the work|Drafting the work|Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	-	-	NO
5481406	28690620	GR	1	Contributions to the conception or design of the work|Drafting the work|Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Contributions to the conception or design of the work	Conceived and designed the experiments	Conceptualization	YES
5481406	28690620	GR	1	Contributions to the conception or design of the work|Drafting the work|Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Drafting the work	Wrote the paper	Writing - Original Draft	YES
5481406	28690620	GR	1	Contributions to the conception or design of the work|Drafting the work|Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	-	-	NO
5481406	28690620	LM	1	Contributions to the conception or design of the work|Drafting the work|Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Contributions to the conception or design of the work	Conceived and designed the experiments	Conceptualization	YES
5481406	28690620	LM	1	Contributions to the conception or design of the work|Drafting the work|Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Drafting the work	Wrote the paper	Writing - Original Draft	YES
5481406	28690620	LM	1	Contributions to the conception or design of the work|Drafting the work|Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	-	-	NO
5481406	28690620	MM	1	Manuscript writing and critical review|Final approval of the version to be published|Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Manuscript writing and critical review	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5481406	28690620	MM	1	Manuscript writing and critical review|Final approval of the version to be published|Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Final approval of the version to be published	-	-	NO
5481406	28690620	MM	1	Manuscript writing and critical review|Final approval of the version to be published|Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	-	-	NO
5481406	28690620	MT	1	Contributed equally to this work|Contributions to the conception or design of the work|Drafting the work|Manuscript writing and critical review|Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Contributed equally to this work	-	-	NO
5481406	28690620	MT	1	Contributed equally to this work|Contributions to the conception or design of the work|Drafting the work|Manuscript writing and critical review|Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Contributions to the conception or design of the work	Conceived and designed the experiments	Conceptualization	YES
5481406	28690620	MT	1	Contributed equally to this work|Contributions to the conception or design of the work|Drafting the work|Manuscript writing and critical review|Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Drafting the work	Wrote the paper	Writing - Original Draft	YES
5481406	28690620	MT	1	Contributed equally to this work|Contributions to the conception or design of the work|Drafting the work|Manuscript writing and critical review|Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Manuscript writing and critical review	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5481406	28690620	MT	1	Contributed equally to this work|Contributions to the conception or design of the work|Drafting the work|Manuscript writing and critical review|Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	-	-	NO
5481406	28690620	PA	1	Contributions to the conception or design of the work|Drafting the work|Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Contributions to the conception or design of the work	Conceived and designed the experiments	Conceptualization	YES
5481406	28690620	PA	1	Contributions to the conception or design of the work|Drafting the work|Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Drafting the work	Wrote the paper	Writing - Original Draft	YES
5481406	28690620	PA	1	Contributions to the conception or design of the work|Drafting the work|Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	-	-	NO
5481406	28690620	PL	1	Manuscript writing and critical review|Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Manuscript writing and critical review	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5481406	28690620	PL	1	Manuscript writing and critical review|Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	-	-	NO
5481406	28690620	TF	1	Contributed equally to this work|Contributions to the conception or design of the work|Drafting the work|Manuscript writing and critical review|Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Contributed equally to this work	-	-	NO
5481406	28690620	TF	1	Contributed equally to this work|Contributions to the conception or design of the work|Drafting the work|Manuscript writing and critical review|Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Contributions to the conception or design of the work	Conceived and designed the experiments	Conceptualization	YES
5481406	28690620	TF	1	Contributed equally to this work|Contributions to the conception or design of the work|Drafting the work|Manuscript writing and critical review|Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Drafting the work	Wrote the paper	Writing - Original Draft	YES
5481406	28690620	TF	1	Contributed equally to this work|Contributions to the conception or design of the work|Drafting the work|Manuscript writing and critical review|Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Manuscript writing and critical review	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5481406	28690620	TF	1	Contributed equally to this work|Contributions to the conception or design of the work|Drafting the work|Manuscript writing and critical review|Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	-	-	NO
5481406	28690620	VG	1	Contributions to the conception or design of the work|Drafting the work|Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Contributions to the conception or design of the work	Conceived and designed the experiments	Conceptualization	YES
5481406	28690620	VG	1	Contributions to the conception or design of the work|Drafting the work|Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Drafting the work	Wrote the paper	Writing - Original Draft	YES
5481406	28690620	VG	1	Contributions to the conception or design of the work|Drafting the work|Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	-	-	NO
4401700	25886510	AMZ	CRediT	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|methodology	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401700	25886510	AMZ	CRediT	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|methodology	Performed the experiments	Performed the experiments	Investigation	YES
4401700	25886510	AMZ	CRediT	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|methodology	Analyzed the data	Analyzed the data	Formal analysis	YES
4401700	25886510	AMZ	CRediT	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|methodology	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401700	25886510	AMZ	CRediT	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|methodology	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401700	25886510	AMZ	CRediT	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|methodology	methodology	Performed the experiments	Methodology	YES
4401700	25886510	BQK	CRediT	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401700	25886510	BQK	CRediT	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401700	25886510	GWL	CRediT	Contributed reagents/materials/analysis tools|methodology	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401700	25886510	GWL	CRediT	Contributed reagents/materials/analysis tools|methodology	methodology	Performed the experiments	Methodology	YES
4401700	25886510	YRG	CRediT	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401700	25886510	YRG	CRediT	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3136401	21708049	AE	2	contributed to the manuscript preparation and to data analyses of the study	contributed to the manuscript preparation and to data analyses of the study	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
3136401	21708049	AL	2	performed the purification and quantification of memory cells and the cytokine analyses under the	performed the purification and quantification of memory cells and the cytokine analyses under the	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3136401	21708049	AS	2	supervised the performed the purification and quantification of memory cells and the cytokine analyses under the	supervised the performed the purification and quantification of memory cells and the cytokine analyses under the	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Supervision	YES
3136401	21708049	All of the authors	2	contributed to the manuscript preparation and all have seen and approved the final version	contributed to the manuscript preparation and all have seen and approved the final version	Wrote the paper	Writing - Original Draft	YES
3136401	21708049	MG	2	originated the idea, designed the study, recruited the participants and performed data analysis|supervised the study including execution and interpretation and manuscript preparation	originated the idea, designed the study, recruited the participants and performed data analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation|Methodology	YES
3136401	21708049	MG	2	originated the idea, designed the study, recruited the participants and performed data analysis|supervised the study including execution and interpretation and manuscript preparation	supervised the study including execution and interpretation and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Supervision|Writing - Original Draft	YES
3136401	21708049	TM	2	performed data analyses and wrote the article	performed data analyses and wrote the article	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3136401	21708049	VDG	2	conducted the t-cell analysis	conducted the t-cell analysis	Performed the experiments	Investigation	YES
4286879	25580451	AHS	2	conceptualized and designed the mortality study|directed mortality data collection and coding of death certificates|drafted the paper|critically reviewed the manuscript and suggested revisions	conceptualized and designed the mortality study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4286879	25580451	AHS	2	conceptualized and designed the mortality study|directed mortality data collection and coding of death certificates|drafted the paper|critically reviewed the manuscript and suggested revisions	directed mortality data collection and coding of death certificates	Performed the experiments	Investigation|Supervision	YES
4286879	25580451	AHS	2	conceptualized and designed the mortality study|directed mortality data collection and coding of death certificates|drafted the paper|critically reviewed the manuscript and suggested revisions	drafted the paper	Wrote the paper	Writing - Original Draft	YES
4286879	25580451	AHS	2	conceptualized and designed the mortality study|directed mortality data collection and coding of death certificates|drafted the paper|critically reviewed the manuscript and suggested revisions	critically reviewed the manuscript and suggested revisions	Wrote the paper	Writing - Review & Editing	YES
4286879	25580451	CF	2	conceptualized and designed the mortality study|critically reviewed the manuscript and suggested revisions	conceptualized and designed the mortality study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4286879	25580451	CF	2	conceptualized and designed the mortality study|critically reviewed the manuscript and suggested revisions	critically reviewed the manuscript and suggested revisions	Wrote the paper	Writing - Review & Editing	YES
4286879	25580451	CS	2	conceptualized and designed the mortality study|critically reviewed the manuscript and suggested revisions	conceptualized and designed the mortality study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4286879	25580451	CS	2	conceptualized and designed the mortality study|critically reviewed the manuscript and suggested revisions	critically reviewed the manuscript and suggested revisions	Wrote the paper	Writing - Review & Editing	YES
4286879	25580451	GM	2	conceptualized and designed the mortality study|directed mortality data collection and coding of death certificates	conceptualized and designed the mortality study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4286879	25580451	GM	2	conceptualized and designed the mortality study|directed mortality data collection and coding of death certificates	directed mortality data collection and coding of death certificates	Performed the experiments	Investigation|Supervision	YES
4286879	25580451	JL	2	drafted the paper|critically reviewed the manuscript and suggested revisions	drafted the paper	Wrote the paper	Writing - Original Draft	YES
4286879	25580451	JL	2	drafted the paper|critically reviewed the manuscript and suggested revisions	critically reviewed the manuscript and suggested revisions	Wrote the paper	Writing - Review & Editing	YES
4286879	25580451	MTS	2	critically reviewed the manuscript and suggested revisions	critically reviewed the manuscript and suggested revisions	Wrote the paper	Writing - Review & Editing	YES
4286879	25580451	YY	2	drafted the paper|critically reviewed the manuscript and suggested revisions	drafted the paper	Wrote the paper	Writing - Original Draft	YES
4286879	25580451	YY	2	drafted the paper|critically reviewed the manuscript and suggested revisions	critically reviewed the manuscript and suggested revisions	Wrote the paper	Writing - Review & Editing	YES
5120500	27875980	BLAST	2	hits analysis	hits analysis	-	-	NO
5120500	27875980	NGS	2	data interpretation support and paper review	data interpretation support and paper review	Analyzed the data	Formal analysis	YES
5481850	28690623	AH	2	provided background data from their prior publications, recommended scientific approaches to the data set to help guide the discussion, and helped to edit various drafts	provided background data from their prior publications, recommended scientific approaches to the data set to help guide the discussion, and helped to edit various drafts	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Original Draft	YES
5481850	28690623	BG	2	helped with ideas and edits	helped with ideas and edits	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5481850	28690623	RO	2	acquired the background data where necessary, conducted the statistical analyses and helped write the paper	acquired the background data where necessary, conducted the statistical analyses and helped write the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5481850	28690623	TV	2	conceptualized the review and the pertinent relationships to explore, obtained the requisite funding, and helped write the paper	conceptualized the review and the pertinent relationships to explore, obtained the requisite funding, and helped write the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Funding acquisition|Writing - Original Draft|Writing - Review & Editing	YES
5481850	28690623	The authors	2	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	Performed the experiments	Investigation	YES
4401701	25885924	FG	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401701	25885924	FG	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401701	25885924	FG	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401701	25885924	FH	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4401701	25885924	FH	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401701	25885924	XW	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401701	25885924	XW	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401701	25885924	XW	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401701	25885924	XW	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3143919	21729332	AG	PLoS52	the hiv surveillance group collected data and notified the cases, and participated in writing and revised critically the manuscript	the hiv surveillance group collected data and notified the cases, and participated in writing and revised critically the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
3143919	21729332	AM	PLoS52	the hiv surveillance group collected data and notified the cases, and participated in writing and revised critically the manuscript	the hiv surveillance group collected data and notified the cases, and participated in writing and revised critically the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
3143919	21729332	All authors	PLoS52	have reviewed and approved the final manuscript	have reviewed and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
3143919	21729332	CM	PLoS52	the hiv surveillance group collected data and notified the cases, and participated in writing and revised critically the manuscript	the hiv surveillance group collected data and notified the cases, and participated in writing and revised critically the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
3143919	21729332	ER	PLoS52	the hiv surveillance group collected data and notified the cases, and participated in writing and revised critically the manuscript	the hiv surveillance group collected data and notified the cases, and participated in writing and revised critically the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
3143919	21729332	HK	PLoS52	the hiv surveillance group collected data and notified the cases, and participated in writing and revised critically the manuscript	the hiv surveillance group collected data and notified the cases, and participated in writing and revised critically the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
3143919	21729332	IO	PLoS52	the hiv surveillance group collected data and notified the cases, and participated in writing and revised critically the manuscript	the hiv surveillance group collected data and notified the cases, and participated in writing and revised critically the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
3143919	21729332	JAC	PLoS52	designed the study, interpreted the data, and drafted the manuscript	designed the study, interpreted the data, and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3143919	21729332	JMM	PLoS52	the hiv surveillance group collected data and notified the cases, and participated in writing and revised critically the manuscript	the hiv surveillance group collected data and notified the cases, and participated in writing and revised critically the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
3143919	21729332	MAS	PLoS52	the hiv surveillance group collected data and notified the cases, and participated in writing and revised critically the manuscript	the hiv surveillance group collected data and notified the cases, and participated in writing and revised critically the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
3143919	21729332	MJB	PLoS52	analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
3143919	21729332	PD	PLoS52	the hiv surveillance group collected data and notified the cases, and participated in writing and revised critically the manuscript	the hiv surveillance group collected data and notified the cases, and participated in writing and revised critically the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
3143919	21729332	PGdeO	PLoS52	designed the study, interpreted the data, and drafted the manuscript|analysed the data	designed the study, interpreted the data, and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3143919	21729332	PGdeO	PLoS52	designed the study, interpreted the data, and drafted the manuscript|analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
3143919	21729332	VH	PLoS52	the hiv surveillance group collected data and notified the cases, and participated in writing and revised critically the manuscript	the hiv surveillance group collected data and notified the cases, and participated in writing and revised critically the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
4292938	25599086	All authors	2	have made significant and substantive contributions to the study|reviewed and revised the paper	have made significant and substantive contributions to the study	-	-	NO
4292938	25599086	All authors	2	have made significant and substantive contributions to the study|reviewed and revised the paper	reviewed and revised the paper	Wrote the paper	Writing - Review & Editing	YES
4292938	25599086	F.M.U.	2	was the nih-funded principal investigator who directed and supervised this study, including the preparation of the nanoparticles and wrote the final manuscript	was the nih-funded principal investigator who directed and supervised this study, including the preparation of the nanoparticles and wrote the final manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Funding acquisition|Investigation|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
4292938	25599086	J.C.	2	provided the polypeptides	provided the polypeptides	Performed the experiments	Investigation	YES
4292938	25599086	L.Y.	2	provided the polypeptides	provided the polypeptides	Performed the experiments	Investigation	YES
4292938	25599086	PCR	2	rt pcr	rt pcr	Performed the experiments	Investigation	YES
4292938	25599086	RNA	2	rt pcr	rt pcr	Performed the experiments	Investigation	YES
4292938	25599086	S.Q.	2	performed the bioinformatics and statistical analyses	performed the bioinformatics and statistical analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3415160	22919330	Barboza Corona	2	contributed equally to this work	contributed equally to this work	-	-	NO
3415160	22919330	J. Eleazar	2	contributed equally to this work	contributed equally to this work	-	-	NO
3150241	21767368	ANRJ	2	participated in the study concept and design, had full access to all of the data, carried out acquisition, analysis, and interpretation of the data, drafted the manuscript	participated in the study concept and design, had full access to all of the data, carried out acquisition, analysis, and interpretation of the data, drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
3150241	21767368	JH	2	participated in the study concept and design, had full access to all of the data, carried out analysis, and interpretation of the data, drafted the manuscript	participated in the study concept and design, had full access to all of the data, carried out analysis, and interpretation of the data, drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
3150241	21767368	LHM	2	participated in the study conception and design, and acquisition of data	participated in the study conception and design, and acquisition of data	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
3150241	21767368	NH	2	carried out interpretation of the data, revising critically the manuscript	carried out interpretation of the data, revising critically the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
5481953	28690625	CH	PLoS52	designed the experiment	designed the experiment	Conceived and designed the experiments	Methodology	YES
5481953	28690625	QT	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5481953	28690625	SW	PLoS52	designed the experiment|performed the experiment|analyzed the data|wrote the manuscript	designed the experiment	Conceived and designed the experiments	Methodology	YES
5481953	28690625	SW	PLoS52	designed the experiment|performed the experiment|analyzed the data|wrote the manuscript	performed the experiment	Performed the experiments	Investigation	YES
5481953	28690625	SW	PLoS52	designed the experiment|performed the experiment|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5481953	28690625	SW	PLoS52	designed the experiment|performed the experiment|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5481953	28690625	SX	PLoS52	performed the experiment	performed the experiment	Performed the experiments	Investigation	YES
5481953	28690625	XS	PLoS52	designed the experiment|wrote the manuscript	designed the experiment	Conceived and designed the experiments	Methodology	YES
5481953	28690625	XS	PLoS52	designed the experiment|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4401702	25886402	ALS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401702	25886402	AMS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401702	25886402	AMS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401702	25886402	AMS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401702	25886402	BK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401702	25886402	BK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401702	25886402	BK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401702	25886402	BP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Recruited the participants	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401702	25886402	BP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Recruited the participants	Analyzed the data	Analyzed the data	Formal analysis	YES
4401702	25886402	BP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Recruited the participants	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401702	25886402	BP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Recruited the participants	Recruited the participants	Performed the experiments	Investigation	YES
4401702	25886402	HF	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401702	25886402	HF	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401702	25886402	HF	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401702	25886402	IK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401702	25886402	IL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401702	25886402	LK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401702	25886402	PS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401702	25886402	PS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401702	25886402	PS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401702	25886402	PS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401702	25886402	RGF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401702	25886402	RGF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401702	25886402	RGF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401702	25886402	RGF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401702	25886402	SR	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401702	25886402	SRD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Recruited the participants	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401702	25886402	SRD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Recruited the participants	Performed the experiments	Performed the experiments	Investigation	YES
4401702	25886402	SRD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Recruited the participants	Analyzed the data	Analyzed the data	Formal analysis	YES
4401702	25886402	SRD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Recruited the participants	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401702	25886402	SRD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Recruited the participants	Recruited the participants	Performed the experiments	Investigation	YES
4401702	25886402	WS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401702	25886402	WS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401702	25886402	WS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401702	25886402	WS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5120521	27875995	All authors	2	have read, corrected and approved the final manuscript	have read, corrected and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5120521	27875995	BD	2	participated in developing the microfluidic 96	participated in developing the microfluidic 96	-	-	NO
5120521	27875995	MFCC	2	conceived the study, participated in its design and coordination and helped to draft the manuscript	conceived the study, participated in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
5120521	27875995	NM	2	undertook bioinformatic research and carried out the primer design	undertook bioinformatic research and carried out the primer design	Conceived and designed the experiments|Performed the experiments	Formal analysis|Investigation	YES
5120521	27875995	SV	2	participated in developing the microfluidic 96	participated in developing the microfluidic 96	-	-	NO
4450213	26090383	Chen Wu	2	contributed equally to this study	contributed equally to this study	-	-	NO
3152879	21774813	AJ	2	gave overall support and helped to draft the manuscript	gave overall support and helped to draft the manuscript	Wrote the paper	Writing - Original Draft	YES
3152879	21774813	FO	2	participated in the clinical care of the patients	participated in the clinical care of the patients	Performed the experiments	Investigation	YES
3152879	21774813	IP	2	contributed to the design of the study	contributed to the design of the study	Conceived and designed the experiments	Methodology	YES
3152879	21774813	KP	2	participated in the clinical care of the patients	participated in the clinical care of the patients	Performed the experiments	Investigation	YES
3152879	21774813	SJ	2	conceived of the idea and participated in the study design	conceived of the idea and participated in the study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
3152879	21774813	TT	2	co-ordinated the hiv clinical and field activities, performed the statistical analysis and drafted the manuscript|participated in the clinical care of the patients	co-ordinated the hiv clinical and field activities, performed the statistical analysis and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Project administration|Writing - Original Draft	YES
3152879	21774813	TT	2	co-ordinated the hiv clinical and field activities, performed the statistical analysis and drafted the manuscript|participated in the clinical care of the patients	participated in the clinical care of the patients	Performed the experiments	Investigation	YES
3152879	21774813	UO	2	participated in the clinical care of the patients	participated in the clinical care of the patients	Performed the experiments	Investigation	YES
4401703	25884393	GDA	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401703	25884393	MTV	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401703	25884393	MTV	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401703	25884393	PHZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401703	25884393	PHZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401703	25884393	PHZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401703	25884393	RB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401703	25884393	RB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401703	25884393	RB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401703	25884393	RKP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401703	25884393	ZR	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5483447	28694814	AJ	PLoS52	provided access to the root hair mutants|wrote the manuscript	provided access to the root hair mutants	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5483447	28694814	AJ	PLoS52	provided access to the root hair mutants|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5483447	28694814	All authors	PLoS52	discussed the results and commented on the manuscript	discussed the results and commented on the manuscript	-	-	NO
5483447	28694814	BC	PLoS52	generated the microscopic images of wild-type and root hair mutant plants	generated the microscopic images of wild-type and root hair mutant plants	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
5483447	28694814	DB	PLoS52	conceived of and designed the experiments|analyzed the data|wrote the manuscript	conceived of and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5483447	28694814	DB	PLoS52	conceived of and designed the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5483447	28694814	DB	PLoS52	conceived of and designed the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5483447	28694814	IS	PLoS52	provided access to the root hair mutants	provided access to the root hair mutants	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5483447	28694814	JK	PLoS52	generated the microscopic images of wild-type and root hair mutant plants	generated the microscopic images of wild-type and root hair mutant plants	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
5483447	28694814	JM	PLoS52	generated the sequencing information	generated the sequencing information	Performed the experiments	Investigation	YES
5483447	28694814	KB	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5483447	28694814	MB	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5483447	28694814	PH	PLoS52	generated the sequencing information|wrote the manuscript	generated the sequencing information	Performed the experiments	Investigation	YES
5483447	28694814	PH	PLoS52	generated the sequencing information|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5483447	28694814	RAT	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5483447	28694814	SR-A	PLoS52	conceived of and designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	conceived of and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5483447	28694814	SR-A	PLoS52	conceived of and designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5483447	28694814	SR-A	PLoS52	conceived of and designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5483447	28694814	SR-A	PLoS52	conceived of and designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5483447	28694814	TG	PLoS52	provided access to the tayport soil|wrote the manuscript	provided access to the tayport soil	-	-	NO
5483447	28694814	TG	PLoS52	provided access to the tayport soil|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3154141	21787384	LAM	2	contributed to the design, statistical analysis, interpretation of the data and provided substantial input to the intellectual content of the manuscript	contributed to the design, statistical analysis, interpretation of the data and provided substantial input to the intellectual content of the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
3154141	21787384	NC	2	contributed to study design, data collection, statistical analysis, interpretation of the data, and drafted the manuscript	contributed to study design, data collection, statistical analysis, interpretation of the data, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
3154141	21787384	PFS	2	contributed to study design and provided revisions of the manuscript	contributed to study design and provided revisions of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
3154141	21787384	TT	2	contributed to study design, drafting of manuscript and provided valuable administrative support	contributed to study design, drafting of manuscript and provided valuable administrative support	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft	YES
4401704	25884946	FKC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401704	25884946	HYG	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401704	25884946	JL	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401704	25884946	KL	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401704	25884946	LFL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401704	25884946	XMS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401704	25884946	XPC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401704	25884946	YGL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401704	25884946	YTW	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401704	25884946	ZL	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401704	25884946	ZL	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401704	25884946	ZLS	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3162516	21794106	AA	2	assisted with database issues, interpretation of results, and insight into hiv-1 drug resistance and drug resistance testing	assisted with database issues, interpretation of results, and insight into hiv-1 drug resistance and drug resistance testing	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Software	YES
3162516	21794106	AS	2	participated in gathering the data and critically revised the manuscript	participated in gathering the data and critically revised the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
3162516	21794106	AT	2	assisted with literature suggestions, modifications to the methods, and interpret the results	assisted with literature suggestions, modifications to the methods, and interpret the results	Performed the experiments|Analyzed the data	Formal analysis	YES
3162516	21794106	GL	2	designed the study, performed the statistical analysis, and wrote the text	designed the study, performed the statistical analysis, and wrote the text	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3162516	21794106	MZ	2	participated in gathering the data and critically revised the manuscript	participated in gathering the data and critically revised the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
3162516	21794106	TL	2	provided scientific guidance, critically read the text, and suggested points of interpretation	provided scientific guidance, critically read the text, and suggested points of interpretation	Analyzed the data|Wrote the paper	Formal analysis|Supervision|Writing - Original Draft	YES
4326653	25685830	AL	2	was involved in retrieving the clinical data from the medical records and critiquing the manuscript	was involved in retrieving the clinical data from the medical records and critiquing the manuscript	-	-	NO
4326653	25685830	DGH	2	performed most of the final bioinformatics and participated in writing the manuscript	performed most of the final bioinformatics and participated in writing the manuscript	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4326653	25685830	JAR	2	was involved in discussing and critiquing the findings throughout the study and editing the manuscript	was involved in discussing and critiquing the findings throughout the study and editing the manuscript	Wrote the paper	Writing - Review & Editing	YES
4326653	25685830	JHB	2	was involved in discussing the initial concepts and conducting the in-house clinical study as well as editing the manuscript	was involved in discussing the initial concepts and conducting the in-house clinical study as well as editing the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Review & Editing	YES
4326653	25685830	JX	2	was involved in initial bioinformatic analyses, especially network analyses, and provided essential advice regarding determining diagnostic accuracy	was involved in initial bioinformatic analyses, especially network analyses, and provided essential advice regarding determining diagnostic accuracy	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4326653	25685830	NHL	2	was involved in retrieving the clinical data from the medical records and editing the manuscript	was involved in retrieving the clinical data from the medical records and editing the manuscript	Wrote the paper	Writing - Review & Editing	YES
4326653	25685830	OMP	2	was involved in defining the initial concept and designing the study, discovering the endotoxin tolerance signature, and writing the manuscript	was involved in defining the initial concept and designing the study, discovering the endotoxin tolerance signature, and writing the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
4326653	25685830	REWH	2	was involved in defining the initial concept and design of the study, supervising all aspects of the research, and in extensively editing the manuscript	was involved in defining the initial concept and design of the study, supervising all aspects of the research, and in extensively editing the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Supervision|Writing - Review & Editing	YES
3800718	24151452	JG	1	Data analyses, results writing, and critical revision of manuscript for its content	Data analyses, results writing, and critical revision of manuscript for its content	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
3800718	24151452	LL	1	Conception, design, manuscript drafting, and supervision of data collection	Conception, design, manuscript drafting, and supervision of data collection	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Supervision|Writing - Original Draft	YES
5120530	27875996	AMF	2	performed the qpcr validation	performed the qpcr validation	Performed the experiments	Investigation|Validation	YES
5120530	27875996	ASC	2	conducted animal experiments	conducted animal experiments	Performed the experiments	Investigation	YES
5120530	27875996	ASMC	2	conceived the idea of this research|participated in the experimental design and rna sequencing|performed the qpcr validation|performed data analysis|drafted the manuscript	conceived the idea of this research	Conceived and designed the experiments	Conceptualization	YES
5120530	27875996	ASMC	2	conceived the idea of this research|participated in the experimental design and rna sequencing|performed the qpcr validation|performed data analysis|drafted the manuscript	participated in the experimental design and rna sequencing	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5120530	27875996	ASMC	2	conceived the idea of this research|participated in the experimental design and rna sequencing|performed the qpcr validation|performed data analysis|drafted the manuscript	performed the qpcr validation	Performed the experiments	Investigation|Validation	YES
5120530	27875996	ASMC	2	conceived the idea of this research|participated in the experimental design and rna sequencing|performed the qpcr validation|performed data analysis|drafted the manuscript	performed data analysis	Analyzed the data	Formal analysis	YES
5120530	27875996	ASMC	2	conceived the idea of this research|participated in the experimental design and rna sequencing|performed the qpcr validation|performed data analysis|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5120530	27875996	AZN	2	provided the experimental environment and coordination	provided the experimental environment and coordination	-	Project administration	YES
5120530	27875996	DPDL	2	conceived the idea of this research	conceived the idea of this research	Conceived and designed the experiments	Conceptualization	YES
5120530	27875996	EFW	2	performed data analysis	performed data analysis	Analyzed the data	Formal analysis	YES
5120530	27875996	GBM	2	provided the experimental environment and coordination	provided the experimental environment and coordination	-	Project administration	YES
5120530	27875996	JEK	2	performed data analysis	performed data analysis	Analyzed the data	Formal analysis	YES
5120530	27875996	JMR	2	provided the experimental environment and coordination	provided the experimental environment and coordination	-	Project administration	YES
5120530	27875996	JR	2	conceived the idea of this research	conceived the idea of this research	Conceived and designed the experiments	Conceptualization	YES
5120530	27875996	LCAR	2	conceived the idea of this research|provided the experimental environment and coordination	conceived the idea of this research	Conceived and designed the experiments	Conceptualization	YES
5120530	27875996	LCAR	2	conceived the idea of this research|provided the experimental environment and coordination	provided the experimental environment and coordination	-	Project administration	YES
5120530	27875996	LLC	2	conceived the idea of this research|provided the experimental environment and coordination	conceived the idea of this research	Conceived and designed the experiments	Conceptualization	YES
5120530	27875996	LLC	2	conceived the idea of this research|provided the experimental environment and coordination	provided the experimental environment and coordination	-	Project administration	YES
5120530	27875996	MDP	2	participated in the experimental design and rna sequencing	participated in the experimental design and rna sequencing	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5120530	27875996	MLN	2	conducted animal experiments	conducted animal experiments	Performed the experiments	Investigation	YES
5120530	27875996	RRT	2	conceived the idea of this research|conducted animal experiments	conceived the idea of this research	Conceived and designed the experiments	Conceptualization	YES
5120530	27875996	RRT	2	conceived the idea of this research|conducted animal experiments	conducted animal experiments	Performed the experiments	Investigation	YES
5120530	27875996	RTN	2	conceived the idea of this research	conceived the idea of this research	Conceived and designed the experiments	Conceptualization	YES
5120530	27875996	SCSA	2	performed data analysis	performed data analysis	Analyzed the data	Formal analysis	YES
4450215	26090407	Goh Kobayashi	2	equally contributed to this paper	equally contributed to this paper	-	-	NO
4450215	26090407	Yumie Ono	2	equally contributed to this paper	equally contributed to this paper	-	-	NO
4777268	26977294	De Grassi	2	conducted experiments	conducted experiments	Performed the experiments	Investigation	YES
5483458	28694818	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5483458	28694818	BE	2	carried out such experiments and participated in data analysis	carried out such experiments and participated in data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5483458	28694818	LG	2	contributed to drafting the manuscript as well as to the design of the experiments and to data analysis	contributed to drafting the manuscript as well as to the design of the experiments and to data analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
5483458	28694818	ML	2	reviewed the literature and wrote the paper and designed the experiments leading to data shown	reviewed the literature and wrote the paper and designed the experiments leading to data shown	Conceived and designed the experiments|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
4401705	25885636	AIV	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401705	25885636	AIV	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401705	25885636	AIV	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401705	25885636	EJD	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401705	25885636	PPR	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401705	25885636	PPR	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401705	25885636	YCK	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401705	25885636	YCV	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3163174	21831314	BC	2	clinical care and sample collection	clinical care and sample collection	Performed the experiments	Investigation	YES
3163174	21831314	CB	2	clinical care and sample collection	clinical care and sample collection	Performed the experiments	Investigation	YES
3163174	21831314	DW	2	clinical care and sample collection	clinical care and sample collection	Performed the experiments	Investigation	YES
3163174	21831314	FT	2	clinical care and sample collection	clinical care and sample collection	Performed the experiments	Investigation	YES
3163174	21831314	G Implemented	2	modified version of symptom inventory used in present study and critical feed-back in redaction of manuscript	modified version of symptom inventory used in present study and critical feed-back in redaction of manuscript	Wrote the paper	Writing - Review & Editing	YES
3163174	21831314	M Clinical	2	care with sample collection, study design, data analyses and manuscript preparation	care with sample collection, study design, data analyses and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
3163174	21831314	MG	2	clinical care and sample collection	clinical care and sample collection	Performed the experiments	Investigation	YES
4450216	26090401	all authors	2	have made significant contribution to the content of this paper|have made significant contribution to the content of this paper	have made significant contribution to the content of this paper	-	-	NO
4450216	26090401	all authors	2	have made significant contribution to the content of this paper|have made significant contribution to the content of this paper	have made significant contribution to the content of this paper	-	-	NO
4337426	25717475	BT	2	performed and designed experiments, analyzed data and edited the manuscript	performed and designed experiments, analyzed data and edited the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Review & Editing	YES
4337426	25717475	DT	2	performed experiments and analyzed data	performed experiments and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4337426	25717475	EMZ	2	advised and edited the manuscript	advised and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
4337426	25717475	GAM	2	provided human samples	provided human samples	Contributed reagents/materials/analysis tools	Resources	YES
4337426	25717475	MK	2	provided human samples	provided human samples	Contributed reagents/materials/analysis tools	Resources	YES
4337426	25717475	MZ	2	designed, performed and supervised experiments, analyzed data and wrote the manuscript	designed, performed and supervised experiments, analyzed data and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Supervision|Writing - Original Draft	YES
4337426	25717475	RK	2	edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
4337426	25717475	WBW	2	performed experiments and analyzed data	performed experiments and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3170178	21846370	All authors	2	have provided editorial content and have approved this final manuscript	have provided editorial content and have approved this final manuscript	Wrote the paper	Writing - Review & Editing	YES
3170178	21846370	CC	2	was responsible for real time pcr and histology	was responsible for real time pcr and histology	Performed the experiments	Investigation	YES
3170178	21846370	DG	2	was responsible for tissue preparation, protein content analyses and data collection	was responsible for tissue preparation, protein content analyses and data collection	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3170178	21846370	JO	2	was responsible for study design, research fund collection, figures and manuscript preparations	was responsible for study design, research fund collection, figures and manuscript preparations	Conceived and designed the experiments|Wrote the paper	Methodology|Visualization|Writing - Original Draft	YES
3170178	21846370	MB	2	was responsible for western blot analyses	was responsible for western blot analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5483459	28694819	ACK	2	carried out the design of the experiment|conducted the field and laboratory measurements|analyzed the data and wrote the paper under the supervision of ak and with contributions from all the other authors	carried out the design of the experiment	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5483459	28694819	ACK	2	carried out the design of the experiment|conducted the field and laboratory measurements|analyzed the data and wrote the paper under the supervision of ak and with contributions from all the other authors	conducted the field and laboratory measurements	Performed the experiments	Investigation	YES
5483459	28694819	ACK	2	carried out the design of the experiment|conducted the field and laboratory measurements|analyzed the data and wrote the paper under the supervision of ak and with contributions from all the other authors	analyzed the data and wrote the paper under the supervision of ak and with contributions from all the other authors	Analyzed the data|Wrote the paper	Formal analysis|Supervision|Writing - Original Draft	YES
5483459	28694819	AK	2	carried out the design of the experiment	carried out the design of the experiment	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5483459	28694819	DS	2	carried out the uav flights and processed the aerial imageries	carried out the uav flights and processed the aerial imageries	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
5483459	28694819	GM	2	contributed to the data analysis	contributed to the data analysis	Analyzed the data	Formal analysis	YES
5483459	28694819	VV	2	carried out the uav flights and processed the aerial imageries	carried out the uav flights and processed the aerial imageries	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
5120533	27875998	DXZ	PLoS52	performed the experiment and analysed the data	performed the experiment and analysed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5120533	27875998	HCL	PLoS52	conceived and designed the experiments|supervised the project and revised the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5120533	27875998	HCL	PLoS52	conceived and designed the experiments|supervised the project and revised the manuscript	supervised the project and revised the manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
5120533	27875998	HXJ	PLoS52	conceived and designed the experiments|performed the experiment and analysed the data|interpreted the data and drafted the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5120533	27875998	HXJ	PLoS52	conceived and designed the experiments|performed the experiment and analysed the data|interpreted the data and drafted the manuscript	performed the experiment and analysed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5120533	27875998	HXJ	PLoS52	conceived and designed the experiments|performed the experiment and analysed the data|interpreted the data and drafted the manuscript	interpreted the data and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5120533	27875998	LK	PLoS52	provided helpful discussions on the manuscript	provided helpful discussions on the manuscript	-	-	NO
5120533	27875998	LQJ	PLoS52	provided helpful discussions on the manuscript	provided helpful discussions on the manuscript	-	-	NO
5120533	27875998	LZF	PLoS52	supervised the project and revised the manuscript	supervised the project and revised the manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
5120533	27875998	WH	PLoS52	provided helpful discussions on the manuscript	provided helpful discussions on the manuscript	-	-	NO
5120533	27875998	WHW	PLoS52	conceived and designed the experiments|performed the experiment and analysed the data|supervised the project and revised the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5120533	27875998	WHW	PLoS52	conceived and designed the experiments|performed the experiment and analysed the data|supervised the project and revised the manuscript	performed the experiment and analysed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5120533	27875998	WHW	PLoS52	conceived and designed the experiments|performed the experiment and analysed the data|supervised the project and revised the manuscript	supervised the project and revised the manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
5120533	27875998	WYJ	PLoS52	conducted the field experiments and collected the tissue samples	conducted the field experiments and collected the tissue samples	Performed the experiments	Investigation	YES
3173282	21810224	All	2	have approved the final manuscript	have approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
3173282	21810224	CP	2	have approved the final manuscript	have approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
3173282	21810224	ICB	2	have approved the final manuscript	have approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
3173282	21810224	JG	2	have approved the final manuscript	have approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
3173282	21810224	MGC	2	have approved the final manuscript	have approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
3173282	21810224	MML	2	have approved the final manuscript	have approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4376376	25825707	BL	2	contributed to the study design, data analysis, data interpretation and writing of the report	contributed to the study design, data analysis, data interpretation and writing of the report	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources	YES
4376376	25825707	CI	2	contributed to the study design and data interpretation	contributed to the study design and data interpretation	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Methodology|Resources	YES
4376376	25825707	GX	2	contributed to data analysis	contributed to data analysis	Analyzed the data	Formal analysis	YES
4376376	25825707	HH	2	contributed to the study design and data interpretation	contributed to the study design and data interpretation	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Methodology|Resources	YES
4376376	25825707	HT	2	contributed to the study design, data analysis, data interpretation and writing of the report	contributed to the study design, data analysis, data interpretation and writing of the report	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources	YES
4376376	25825707	MP	2	contributed to the study design, data analysis, data interpretation and writing of the report	contributed to the study design, data analysis, data interpretation and writing of the report	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources	YES
4376376	25825707	RT	2	contributed to the study design and data analysis	contributed to the study design and data analysis	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Methodology|Resources	YES
4376376	25825707	SS	2	contributed to the study design, data analysis, data interpretation and writing of the report	contributed to the study design, data analysis, data interpretation and writing of the report	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources	YES
4376376	25825707	TR	2	contributed to data interpretation and writing of the report	contributed to data interpretation and writing of the report	Analyzed the data|Wrote the paper	Formal analysis	YES
4376376	25825707	YX	2	contributed to the study design, data analysis, data interpretation and writing of the report	contributed to the study design, data analysis, data interpretation and writing of the report	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources	YES
4376376	25825707	YZ	2	contributed to data analysis	contributed to data analysis	Analyzed the data	Formal analysis	YES
5483462	28694813	HK	PLoS52	carried out the field and laboratory work	carried out the field and laboratory work	Performed the experiments	Investigation	YES
5483462	28694813	JM	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5483462	28694813	MK	PLoS52	guided the laboratory analyses|interpreted the data|developed the text	guided the laboratory analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Supervision	YES
5483462	28694813	MK	PLoS52	guided the laboratory analyses|interpreted the data|developed the text	interpreted the data	Analyzed the data	Formal analysis	YES
5483462	28694813	MK	PLoS52	guided the laboratory analyses|interpreted the data|developed the text	developed the text	-	-	NO
5483462	28694813	MR	PLoS52	arranged the plant material|developed the text	arranged the plant material	Performed the experiments	Investigation	YES
5483462	28694813	MR	PLoS52	arranged the plant material|developed the text	developed the text	-	-	NO
5483462	28694813	SK-S	PLoS52	guided the laboratory analyses|interpreted the data|analyzed the data|developed the text	guided the laboratory analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Supervision	YES
5483462	28694813	SK-S	PLoS52	guided the laboratory analyses|interpreted the data|analyzed the data|developed the text	interpreted the data	Analyzed the data	Formal analysis	YES
5483462	28694813	SK-S	PLoS52	guided the laboratory analyses|interpreted the data|analyzed the data|developed the text	analyzed the data	Analyzed the data	Formal analysis	YES
5483462	28694813	SK-S	PLoS52	guided the laboratory analyses|interpreted the data|analyzed the data|developed the text	developed the text	-	-	NO
5483462	28694813	TS	PLoS52	analyzed the data|developed the text	analyzed the data	Analyzed the data	Formal analysis	YES
5483462	28694813	TS	PLoS52	analyzed the data|developed the text	developed the text	-	-	NO
5483462	28694813	UP	PLoS52	carried out the field and laboratory work|interpreted the data|analyzed the data	carried out the field and laboratory work	Performed the experiments	Investigation	YES
5483462	28694813	UP	PLoS52	carried out the field and laboratory work|interpreted the data|analyzed the data	interpreted the data	Analyzed the data	Formal analysis	YES
5483462	28694813	UP	PLoS52	carried out the field and laboratory work|interpreted the data|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
4401708	25885414	AF	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401708	25885414	AF	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401708	25885414	AF	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401708	25885414	AS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401708	25885414	AS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401708	25885414	AS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401708	25885414	AS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401708	25885414	BM	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401708	25885414	BM	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401708	25885414	DG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401708	25885414	DG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401708	25885414	DG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401708	25885414	DG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401708	25885414	DSB	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401708	25885414	DSB	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401708	25885414	IJ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4401708	25885414	IJ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4401708	25885414	IJ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401708	25885414	IK	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401708	25885414	IK	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401708	25885414	IM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401708	25885414	IM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401708	25885414	IM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401708	25885414	IM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401708	25885414	JB	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401708	25885414	LK	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401708	25885414	LK	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401708	25885414	LV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401708	25885414	LV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401708	25885414	LV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401708	25885414	LV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401708	25885414	LV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401708	25885414	MH	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4401708	25885414	MH	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401708	25885414	MP	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401708	25885414	MP	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401708	25885414	MS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4401708	25885414	MS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4401708	25885414	MS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401708	25885414	PM	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4401708	25885414	PM	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401708	25885414	PS	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401708	25885414	PS	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401708	25885414	SA	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4401708	25885414	SA	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4401708	25885414	SA	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401708	25885414	SR	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401708	25885414	SR	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401708	25885414	SS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4401708	25885414	SS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401708	25885414	ZMA	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401708	25885414	ZMA	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5120557	27875984	JGD	2	designed, implemented, and tested the software|wrote the manuscript	designed, implemented, and tested the software	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5120557	27875984	JGD	2	designed, implemented, and tested the software|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5120557	27875984	JSW	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3180248	21892955	BY	2	supervised the data collection and the preparation of the dataset for analysis	supervised the data collection and the preparation of the dataset for analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Supervision	YES
3180248	21892955	DMM	2	conceived of the study, and participated in its design and coordination	conceived of the study, and participated in its design and coordination	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
3180248	21892955	JSGM	2	conceived of the study, and participated in its design and coordination	conceived of the study, and participated in its design and coordination	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
3180248	21892955	KC	2	conducted all of the data analysis	conducted all of the data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3180248	21892955	RSH	2	conceived of the study, and participated in its design and coordination|supervised the data collection and the preparation of the dataset for analysis	conceived of the study, and participated in its design and coordination	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
3180248	21892955	RSH	2	conceived of the study, and participated in its design and coordination|supervised the data collection and the preparation of the dataset for analysis	supervised the data collection and the preparation of the dataset for analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Supervision	YES
3180248	21892955	SJ	2	conceived of the study, and participated in its design and coordination	conceived of the study, and participated in its design and coordination	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
3180248	21892955	VL	2	supervised the data collection and the preparation of the dataset for analysis	supervised the data collection and the preparation of the dataset for analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Supervision	YES
4397954	25893206	AG	PLoS52	contributed new reagents/analytic tools	contributed new reagents/analytic tools	Contributed reagents/materials/analysis tools	Resources	YES
4397954	25893206	BRS	PLoS52	performed the research	performed the research	Performed the experiments	Investigation	YES
4397954	25893206	DHO	PLoS52	designed the research|performed the research|analyzed the data|wrote the paper	designed the research	Conceived and designed the experiments	Methodology	YES
4397954	25893206	DHO	PLoS52	designed the research|performed the research|analyzed the data|wrote the paper	performed the research	Performed the experiments	Investigation	YES
4397954	25893206	DHO	PLoS52	designed the research|performed the research|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
4397954	25893206	DHO	PLoS52	designed the research|performed the research|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397954	25893206	DJPF	PLoS52	designed the research|performed the research|contributed new reagents/analytic tools|analyzed the data|wrote the paper	designed the research	Conceived and designed the experiments	Methodology	YES
4397954	25893206	DJPF	PLoS52	designed the research|performed the research|contributed new reagents/analytic tools|analyzed the data|wrote the paper	performed the research	Performed the experiments	Investigation	YES
4397954	25893206	DJPF	PLoS52	designed the research|performed the research|contributed new reagents/analytic tools|analyzed the data|wrote the paper	contributed new reagents/analytic tools	Contributed reagents/materials/analysis tools	Resources	YES
4397954	25893206	DJPF	PLoS52	designed the research|performed the research|contributed new reagents/analytic tools|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
4397954	25893206	DJPF	PLoS52	designed the research|performed the research|contributed new reagents/analytic tools|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397954	25893206	HF	PLoS52	performed the research	performed the research	Performed the experiments	Investigation	YES
4397954	25893206	HO	PLoS52	performed the research	performed the research	Performed the experiments	Investigation	YES
4397954	25893206	JAR	PLoS52	designed the research|analyzed the data|wrote the paper	designed the research	Conceived and designed the experiments	Methodology	YES
4397954	25893206	JAR	PLoS52	designed the research|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
4397954	25893206	JAR	PLoS52	designed the research|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397954	25893206	LBO	PLoS52	designed the research|performed the research|wrote the paper	designed the research	Conceived and designed the experiments	Methodology	YES
4397954	25893206	LBO	PLoS52	designed the research|performed the research|wrote the paper	performed the research	Performed the experiments	Investigation	YES
4397954	25893206	LBO	PLoS52	designed the research|performed the research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4397954	25893206	MT	PLoS52	performed the research	performed the research	Performed the experiments	Investigation	YES
4397954	25893206	TNW	PLoS52	designed the research|analyzed the data|wrote the paper	designed the research	Conceived and designed the experiments	Methodology	YES
4397954	25893206	TNW	PLoS52	designed the research|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
4397954	25893206	TNW	PLoS52	designed the research|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3415178	22919317	P. Orlandi	2	equally contributed to the study	equally contributed to the study	-	-	NO
3415178	22919317	S. Lazzeri	2	equally contributed to the study	equally contributed to the study	-	-	NO
3809347	24170990	Min Chen	2	was responsible for foundation, conception, and design of the experiments, as well as analysis of experimental data and manuscript writing	was responsible for foundation, conception, and design of the experiments, as well as analysis of experimental data and manuscript writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5483469	28694815	BN	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5483469	28694815	BX	PLoS52	provided assistance on vector construction	provided assistance on vector construction	Performed the experiments	Investigation	YES
5483469	28694815	LX	PLoS52	designed the experiments and wrote the manuscript	designed the experiments and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5483469	28694815	NT	PLoS52	provided assistance on vector construction	provided assistance on vector construction	Performed the experiments	Investigation	YES
5483469	28694815	TM	PLoS52	provided vital advice on the article	provided vital advice on the article	-	-	NO
5483469	28694815	WZ	PLoS52	provided assistance on the drought pre-screening experiment	provided assistance on the drought pre-screening experiment	Performed the experiments	Investigation	YES
5483469	28694815	YC	PLoS52	generated the transgenic materials, designed the experiments, and wrote the manuscript	generated the transgenic materials, designed the experiments, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5483469	28694815	YX	PLoS52	analyzed rna seq data	analyzed rna seq data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4430826	25984558	DAC	2	designed the study|commented on the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
4430826	25984558	DAC	2	designed the study|commented on the manuscript	commented on the manuscript	-	-	NO
4430826	25984558	JEB	2	undertook the bioinformatic analysis|commented on the manuscript	undertook the bioinformatic analysis	Performed the experiments	Formal analysis|Investigation	YES
4430826	25984558	JEB	2	undertook the bioinformatic analysis|commented on the manuscript	commented on the manuscript	-	-	NO
4430826	25984558	MCJM	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
4430826	25984558	MJCM	2	commented on the manuscript	commented on the manuscript	-	-	NO
4430826	25984558	OBH	2	interpreted the data, performed the literature search, made the figures and wrote the manuscript	interpreted the data, performed the literature search, made the figures and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Visualization|Writing - Original Draft	YES
3186736	21939526	AD	2	contributed to the interpretation of the data, have been critically revising the manuscript and have given final approval for publication	contributed to the interpretation of the data, have been critically revising the manuscript and have given final approval for publication	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
3186736	21939526	AJD	2	designed the study, analyzed data and wrote the first draft	designed the study, analyzed data and wrote the first draft	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3186736	21939526	CS	2	contributed to the interpretation of the data, have been critically revising the manuscript and have given final approval for publication	contributed to the interpretation of the data, have been critically revising the manuscript and have given final approval for publication	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
3186736	21939526	FM	2	contributed to the interpretation of the data, have been critically revising the manuscript and have given final approval for publication	contributed to the interpretation of the data, have been critically revising the manuscript and have given final approval for publication	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
3186736	21939526	GO	2	contributed to the interpretation of the data, have been critically revising the manuscript and have given final approval for publication	contributed to the interpretation of the data, have been critically revising the manuscript and have given final approval for publication	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
3186736	21939526	HH	2	designed the study, analyzed data and wrote the first draft	designed the study, analyzed data and wrote the first draft	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3186736	21939526	IG	2	contributed to the interpretation of the data, have been critically revising the manuscript and have given final approval for publication	contributed to the interpretation of the data, have been critically revising the manuscript and have given final approval for publication	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
3186736	21939526	LV	2	designed the study, analyzed data and wrote the first draft	designed the study, analyzed data and wrote the first draft	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3186736	21939526	RV	2	contributed to the interpretation of the data, have been critically revising the manuscript and have given final approval for publication	contributed to the interpretation of the data, have been critically revising the manuscript and have given final approval for publication	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
3186736	21939526	SK	2	contributed to the interpretation of the data, have been critically revising the manuscript and have given final approval for publication	contributed to the interpretation of the data, have been critically revising the manuscript and have given final approval for publication	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
4401709	25884189	BG	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401709	25884189	BG	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401709	25884189	BG	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401709	25884189	GN	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401709	25884189	GY	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401709	25884189	GY	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401709	25884189	IG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401709	25884189	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401709	25884189	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401709	25884189	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401709	25884189	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401709	25884189	JM	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401709	25884189	JM	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401709	25884189	LH	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401709	25884189	LH	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401709	25884189	MC	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401709	25884189	MC	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401709	25884189	ME	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401709	25884189	ME	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401709	25884189	ME	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401709	25884189	ME	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401709	25884189	MP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401709	25884189	MP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401709	25884189	MP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401709	25884189	MP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401709	25884189	RB	PLoS5	Performed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4401709	25884189	RB	PLoS5	Performed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4401709	25884189	RB	PLoS5	Performed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4401709	25884189	RB	PLoS5	Performed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401709	25884189	RK	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401709	25884189	RK	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401709	25884189	RK	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401709	25884189	RK	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401709	25884189	RL	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401709	25884189	RS	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401709	25884189	RS	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4401709	25884189	RS	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401709	25884189	SS	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401709	25884189	SS	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401709	25884189	TT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401709	25884189	TT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401709	25884189	TT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401709	25884189	TT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401709	25884189	TT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401709	25884189	ZH	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5121958	27881075	EB	2	conceived the study and performed the analyses	conceived the study and performed the analyses	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation	YES
5121958	27881075	LP	2	participated in the discussion	participated in the discussion	-	-	NO
5121958	27881075	MF	2	conceived the study and performed the analyses|wrote the manuscript	conceived the study and performed the analyses	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation	YES
5121958	27881075	MF	2	conceived the study and performed the analyses|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5121958	27881075	RF	2	participated in the discussion	participated in the discussion	-	-	NO
5499099	28613074	A.F.H.	2	contributed equally	contributed equally	-	-	NO
5499099	28613074	A.K.P.	2	contributed equally	contributed equally	-	-	NO
3192656	21955517	All authors	2	contributed to the manuscript	contributed to the manuscript	-	-	NO
3192656	21955517	BM	2	was responsible for the final manuscript	was responsible for the final manuscript	Wrote the paper	Writing - Review & Editing	YES
3192656	21955517	CC	2	provided pet-ct images and interpretation	provided pet-ct images and interpretation	Analyzed the data	Formal analysis|Visualization	YES
3192656	21955517	JH	2	were responsible for the primary management of the patient|has given the final approval of the version to be published	were responsible for the primary management of the patient	Performed the experiments	Investigation	YES
3192656	21955517	JH	2	were responsible for the primary management of the patient|has given the final approval of the version to be published	has given the final approval of the version to be published	-	-	NO
3192656	21955517	SN	2	were responsible for the primary management of the patient	were responsible for the primary management of the patient	Performed the experiments	Investigation	YES
4450223	26090397	Jae Yong Lee	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
4450223	26090397	Young-Pil Yun	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
4444225	26023681	AET	2	participated in patient consent, sample acquisition and manuscript edits	participated in patient consent, sample acquisition and manuscript edits	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4444225	26023681	HLH	2	participated in patient consent, sample acquisition and manuscript edits	participated in patient consent, sample acquisition and manuscript edits	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4444225	26023681	JJR	2	interpreted the data and contributed to writing and editing of the manuscript	interpreted the data and contributed to writing and editing of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
4444225	26023681	LD	2	helped interpret the data and isolate dna from patient blood samples	helped interpret the data and isolate dna from patient blood samples	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4444225	26023681	LR	2	participated in patient consent, sample acquisition and manuscript edits	participated in patient consent, sample acquisition and manuscript edits	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4444225	26023681	SBF	2	interpreted the data and contributed to writing and editing of the manuscript	interpreted the data and contributed to writing and editing of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
4444225	26023681	TSR	2	interpreted the data, participated in patient consent and sample acquisition, wrote and edited the manuscript and led the project	interpreted the data, participated in patient consent and sample acquisition, wrote and edited the manuscript and led the project	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
4444225	26023681	VM	2	also interpreted the data and contributed to writing and editing of the manuscript	also interpreted the data and contributed to writing and editing of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5483475	28694817	AJ	2	participated data collection	participated data collection	Performed the experiments	Investigation	YES
5483475	28694817	FW	2	conceived and designed experiments	conceived and designed experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5483475	28694817	HC	2	participated data collection	participated data collection	Performed the experiments	Investigation	YES
5483475	28694817	HL	2	conceived and designed experiments|wrote the manuscript	conceived and designed experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5483475	28694817	HL	2	conceived and designed experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5483475	28694817	NW	2	participated data collection	participated data collection	Performed the experiments	Investigation	YES
5483475	28694817	NY	2	participated data collection	participated data collection	Performed the experiments	Investigation	YES
5483475	28694817	WL	2	conducted most of the experiments|wrote the manuscript	conducted most of the experiments	Performed the experiments	Investigation	YES
5483475	28694817	WL	2	conducted most of the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5483475	28694817	XC	2	participated data collection	participated data collection	Performed the experiments	Investigation	YES
5483475	28694817	XL	2	participated data collection|participated data collection	participated data collection	Performed the experiments	Investigation	YES
5483475	28694817	XL	2	participated data collection|participated data collection	participated data collection	Performed the experiments	Investigation	YES
5483475	28694817	XW	2	participated data collection	participated data collection	Performed the experiments	Investigation	YES
5483475	28694817	YD	2	participated data collection	participated data collection	Performed the experiments	Investigation	YES
5483475	28694817	YZ	2	participated rlm-race experiments	participated rlm-race experiments	Performed the experiments	Investigation	YES
4915515	27347421	A.S.W.	2	participated in research design|conducted experiments|wrote or contributed to the writing of the manuscript	participated in research design	Conceived and designed the experiments	-	YES
4915515	27347421	A.S.W.	2	participated in research design|conducted experiments|wrote or contributed to the writing of the manuscript	conducted experiments	Performed the experiments	Investigation	YES
4915515	27347421	A.S.W.	2	participated in research design|conducted experiments|wrote or contributed to the writing of the manuscript	wrote or contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
4915515	27347421	D.L.	2	participated in research design|wrote or contributed to the writing of the manuscript	participated in research design	Conceived and designed the experiments	-	YES
4915515	27347421	D.L.	2	participated in research design|wrote or contributed to the writing of the manuscript	wrote or contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
4915515	27347421	E.C.Y.W.	2	contributed new reagents or analytical tools|wrote or contributed to the writing of the manuscript	contributed new reagents or analytical tools	Contributed reagents/materials/analysis tools	Resources	YES
4915515	27347421	E.C.Y.W.	2	contributed new reagents or analytical tools|wrote or contributed to the writing of the manuscript	wrote or contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
4915515	27347421	J.O.W.	2	participated in research design|conducted experiments|performed data analysis|wrote or contributed to the writing of the manuscript	participated in research design	Conceived and designed the experiments	-	YES
4915515	27347421	J.O.W.	2	participated in research design|conducted experiments|performed data analysis|wrote or contributed to the writing of the manuscript	conducted experiments	Performed the experiments	Investigation	YES
4915515	27347421	J.O.W.	2	participated in research design|conducted experiments|performed data analysis|wrote or contributed to the writing of the manuscript	performed data analysis	Analyzed the data	Formal analysis	YES
4915515	27347421	J.O.W.	2	participated in research design|conducted experiments|performed data analysis|wrote or contributed to the writing of the manuscript	wrote or contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
3197472	21943115	AFB	2	assisted with the design, interpretation of data and the critical review of the manuscript	assisted with the design, interpretation of data and the critical review of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
3197472	21943115	APK	2	assisted with the design, interpretation of data and the critical review of the manuscript	assisted with the design, interpretation of data and the critical review of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
3197472	21943115	EWPY	2	conceived and designed the study, performed analysis and interpretation of data and drafted the manuscript	conceived and designed the study, performed analysis and interpretation of data and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
3197472	21943115	JFKF	2	performed critical review of the manuscript	performed critical review of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
3197472	21943115	JN	2	performed critical review of the manuscript	performed critical review of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5122016	27881084	AC	2	prepared and quality controlled rna seq samples, and performed preliminary processing of the sequence data	prepared and quality controlled rna seq samples, and performed preliminary processing of the sequence data	Performed the experiments|Analyzed the data	Data curation|Investigation|Validation	YES
5122016	27881084	AW	2	prepared and quality controlled rna seq samples, and performed preliminary processing of the sequence data	prepared and quality controlled rna seq samples, and performed preliminary processing of the sequence data	Performed the experiments|Analyzed the data	Data curation|Investigation|Validation	YES
5122016	27881084	BD	2	prepared and quality controlled rna seq samples, and performed preliminary processing of the sequence data	prepared and quality controlled rna seq samples, and performed preliminary processing of the sequence data	Performed the experiments|Analyzed the data	Data curation|Investigation|Validation	YES
5122016	27881084	CPW	2	prepared and quality controlled rna seq samples, and performed preliminary processing of the sequence data	prepared and quality controlled rna seq samples, and performed preliminary processing of the sequence data	Performed the experiments|Analyzed the data	Data curation|Investigation|Validation	YES
5122016	27881084	HD	2	designed and performed computational analysis|wrote the manuscript	designed and performed computational analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5122016	27881084	HD	2	designed and performed computational analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5122016	27881084	JAK	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5122016	27881084	JE	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5122016	27881084	JF	2	prepared and quality controlled rna seq samples, and performed preliminary processing of the sequence data	prepared and quality controlled rna seq samples, and performed preliminary processing of the sequence data	Performed the experiments|Analyzed the data	Data curation|Investigation|Validation	YES
5122016	27881084	JK	2	designed the study|designed and performed computational analysis|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5122016	27881084	JK	2	designed the study|designed and performed computational analysis|wrote the manuscript	designed and performed computational analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5122016	27881084	JK	2	designed the study|designed and performed computational analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5122016	27881084	JMK	2	prepared and quality controlled rna seq samples, and performed preliminary processing of the sequence data	prepared and quality controlled rna seq samples, and performed preliminary processing of the sequence data	Performed the experiments|Analyzed the data	Data curation|Investigation|Validation	YES
5122016	27881084	JMS	2	prepared and quality controlled rna seq samples, and performed preliminary processing of the sequence data	prepared and quality controlled rna seq samples, and performed preliminary processing of the sequence data	Performed the experiments|Analyzed the data	Data curation|Investigation|Validation	YES
5122016	27881084	JN	2	prepared and quality controlled rna seq samples, and performed preliminary processing of the sequence data	prepared and quality controlled rna seq samples, and performed preliminary processing of the sequence data	Performed the experiments|Analyzed the data	Data curation|Investigation|Validation	YES
5122016	27881084	JS	2	prepared and quality controlled rna seq samples, and performed preliminary processing of the sequence data	prepared and quality controlled rna seq samples, and performed preliminary processing of the sequence data	Performed the experiments|Analyzed the data	Data curation|Investigation|Validation	YES
5122016	27881084	JSH	2	prepared and quality controlled rna seq samples, and performed preliminary processing of the sequence data	prepared and quality controlled rna seq samples, and performed preliminary processing of the sequence data	Performed the experiments|Analyzed the data	Data curation|Investigation|Validation	YES
5122016	27881084	JW	2	prepared and quality controlled rna seq samples, and performed preliminary processing of the sequence data	prepared and quality controlled rna seq samples, and performed preliminary processing of the sequence data	Performed the experiments|Analyzed the data	Data curation|Investigation|Validation	YES
5122016	27881084	KW	2	prepared and quality controlled rna seq samples, and performed preliminary processing of the sequence data	prepared and quality controlled rna seq samples, and performed preliminary processing of the sequence data	Performed the experiments|Analyzed the data	Data curation|Investigation|Validation	YES
5122016	27881084	KZ	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5122016	27881084	LZ	2	prepared and quality controlled rna seq samples, and performed preliminary processing of the sequence data	prepared and quality controlled rna seq samples, and performed preliminary processing of the sequence data	Performed the experiments|Analyzed the data	Data curation|Investigation|Validation	YES
5122016	27881084	MYL	2	prepared and quality controlled rna seq samples, and performed preliminary processing of the sequence data	prepared and quality controlled rna seq samples, and performed preliminary processing of the sequence data	Performed the experiments|Analyzed the data	Data curation|Investigation|Validation	YES
5122016	27881084	NS	2	prepared and quality controlled rna seq samples, and performed preliminary processing of the sequence data	prepared and quality controlled rna seq samples, and performed preliminary processing of the sequence data	Performed the experiments|Analyzed the data	Data curation|Investigation|Validation	YES
5122016	27881084	OVE	2	prepared and quality controlled rna seq samples, and performed preliminary processing of the sequence data	prepared and quality controlled rna seq samples, and performed preliminary processing of the sequence data	Performed the experiments|Analyzed the data	Data curation|Investigation|Validation	YES
5122016	27881084	RA	2	prepared and quality controlled rna seq samples, and performed preliminary processing of the sequence data	prepared and quality controlled rna seq samples, and performed preliminary processing of the sequence data	Performed the experiments|Analyzed the data	Data curation|Investigation|Validation	YES
5122016	27881084	RD	2	prepared and quality controlled rna seq samples, and performed preliminary processing of the sequence data	prepared and quality controlled rna seq samples, and performed preliminary processing of the sequence data	Performed the experiments|Analyzed the data	Data curation|Investigation|Validation	YES
5122016	27881084	RHC	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5122016	27881084	RL	2	prepared and quality controlled rna seq samples, and performed preliminary processing of the sequence data	prepared and quality controlled rna seq samples, and performed preliminary processing of the sequence data	Performed the experiments|Analyzed the data	Data curation|Investigation|Validation	YES
5122016	27881084	SAF	2	prepared and quality controlled rna seq samples, and performed preliminary processing of the sequence data	prepared and quality controlled rna seq samples, and performed preliminary processing of the sequence data	Performed the experiments|Analyzed the data	Data curation|Investigation|Validation	YES
5122016	27881084	SM	2	prepared and quality controlled rna seq samples, and performed preliminary processing of the sequence data	prepared and quality controlled rna seq samples, and performed preliminary processing of the sequence data	Performed the experiments|Analyzed the data	Data curation|Investigation|Validation	YES
5122016	27881084	TKK	2	prepared and quality controlled rna seq samples, and performed preliminary processing of the sequence data	prepared and quality controlled rna seq samples, and performed preliminary processing of the sequence data	Performed the experiments|Analyzed the data	Data curation|Investigation|Validation	YES
5122016	27881084	TS	2	prepared and quality controlled rna seq samples, and performed preliminary processing of the sequence data	prepared and quality controlled rna seq samples, and performed preliminary processing of the sequence data	Performed the experiments|Analyzed the data	Data curation|Investigation|Validation	YES
5122016	27881084	WJM	2	prepared and quality controlled rna seq samples, and performed preliminary processing of the sequence data	prepared and quality controlled rna seq samples, and performed preliminary processing of the sequence data	Performed the experiments|Analyzed the data	Data curation|Investigation|Validation	YES
5122016	27881084	WW	2	prepared and quality controlled rna seq samples, and performed preliminary processing of the sequence data	prepared and quality controlled rna seq samples, and performed preliminary processing of the sequence data	Performed the experiments|Analyzed the data	Data curation|Investigation|Validation	YES
4401711	25886597	ASO	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401711	25886597	JKV	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401711	25886597	JKV	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401711	25886597	JKV	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401711	25886597	JM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401711	25886597	JM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401711	25886597	JM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401711	25886597	JM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401711	25886597	MKJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401711	25886597	MKJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401711	25886597	MKJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401711	25886597	MKJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401711	25886597	MP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401711	25886597	MP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401711	25886597	SB	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401711	25886597	SB	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401711	25886597	TSP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401711	25886597	TSP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401711	25886597	TSP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5483476	28694820	All authors	PLoS52	declared no conflicting interest on the contents of the manuscript	declared no conflicting interest on the contents of the manuscript	-	-	NO
5483476	28694820	CL	PLoS52	provided the technical assistance	provided the technical assistance	Performed the experiments	Investigation	YES
5483476	28694820	HZ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5483476	28694820	JW	PLoS52	conceived the research|provided the mutant material|provided the technical assistance	conceived the research	Conceived and designed the experiments	Conceptualization	YES
5483476	28694820	JW	PLoS52	conceived the research|provided the mutant material|provided the technical assistance	provided the mutant material	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5483476	28694820	JW	PLoS52	conceived the research|provided the mutant material|provided the technical assistance	provided the technical assistance	Performed the experiments	Investigation	YES
5483476	28694820	KZ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5483476	28694820	LL	PLoS52	analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5483476	28694820	LW	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5483476	28694820	LZ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5483476	28694820	WM	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5483476	28694820	XG	PLoS52	provided the technical assistance	provided the technical assistance	Performed the experiments	Investigation	YES
5483476	28694820	XZ	PLoS52	provided the technical assistance	provided the technical assistance	Performed the experiments	Investigation	YES
5483476	28694820	YR	PLoS52	performed the experiments|provided the technical assistance|analyzed the data and wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5483476	28694820	YR	PLoS52	performed the experiments|provided the technical assistance|analyzed the data and wrote the manuscript	provided the technical assistance	Performed the experiments	Investigation	YES
5483476	28694820	YR	PLoS52	performed the experiments|provided the technical assistance|analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5483476	28694820	YX	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5483476	28694820	YiW	PLoS52	conceived the research|performed the experiments|analyzed the data and wrote the manuscript	conceived the research	Conceived and designed the experiments	Conceptualization	YES
5483476	28694820	YiW	PLoS52	conceived the research|performed the experiments|analyzed the data and wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5483476	28694820	YiW	PLoS52	conceived the research|performed the experiments|analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5483476	28694820	YuW	PLoS52	provided the technical assistance	provided the technical assistance	Performed the experiments	Investigation	YES
5483476	28694820	ZC	PLoS52	provided the technical assistance	provided the technical assistance	Performed the experiments	Investigation	YES
5483476	28694820	ZF	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
3417170	22919331	C. Y. Huang	2	contributed equally to this work	contributed equally to this work	-	-	NO
3417170	22919331	K. C. Hung	2	contributed equally to this work	contributed equally to this work	-	-	NO
3198876	21967708	AD	2	carried out the flow cytometry and observed the quality control at the respective sites	carried out the flow cytometry and observed the quality control at the respective sites	Performed the experiments	Investigation|Validation	YES
3198876	21967708	AJ	2	implemented the study at the respective sites|carried out the flow cytometry and observed the quality control at the respective sites	implemented the study at the respective sites	Performed the experiments	Investigation	YES
3198876	21967708	AJ	2	implemented the study at the respective sites|carried out the flow cytometry and observed the quality control at the respective sites	carried out the flow cytometry and observed the quality control at the respective sites	Performed the experiments	Investigation|Validation	YES
3198876	21967708	BB	2	implemented the study at the respective sites	implemented the study at the respective sites	Performed the experiments	Investigation	YES
3198876	21967708	JM	2	carried out the flow cytometry and observed the quality control at the respective sites	carried out the flow cytometry and observed the quality control at the respective sites	Performed the experiments	Investigation|Validation	YES
3198876	21967708	KN	2	carried out the flow cytometry and observed the quality control at the respective sites	carried out the flow cytometry and observed the quality control at the respective sites	Performed the experiments	Investigation|Validation	YES
3198876	21967708	KR	2	implemented the study at the respective sites|implemented the study at the respective sites	implemented the study at the respective sites	Performed the experiments	Investigation	YES
3198876	21967708	KR	2	implemented the study at the respective sites|implemented the study at the respective sites	implemented the study at the respective sites	Performed the experiments	Investigation	YES
3198876	21967708	MT	2	designed the study, implemented at the respective site, performed the data analysis and drafted the manuscript	designed the study, implemented at the respective site, performed the data analysis and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
3198876	21967708	MV	2	implemented the study at the respective sites	implemented the study at the respective sites	Performed the experiments	Investigation	YES
3198876	21967708	PB	2	implemented the study at the respective sites	implemented the study at the respective sites	Performed the experiments	Investigation	YES
3198876	21967708	RP	2	participated in designing the study and writing the manuscript	participated in designing the study and writing the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3198876	21967708	RS	2	carried out the flow cytometry and observed the quality control at the respective sites	carried out the flow cytometry and observed the quality control at the respective sites	Performed the experiments	Investigation|Validation	YES
3198876	21967708	RV	2	implemented the study at the respective sites	implemented the study at the respective sites	Performed the experiments	Investigation	YES
3198876	21967708	SA	2	implemented the study at the respective sites	implemented the study at the respective sites	Performed the experiments	Investigation	YES
3198876	21967708	SP	2	carried out the flow cytometry and observed the quality control at the respective sites	carried out the flow cytometry and observed the quality control at the respective sites	Performed the experiments	Investigation|Validation	YES
4457348	26137522	Luming Chen	1	Conception and design|Collection and assembly of data|Data analysis and interpretation|Manuscript writing|Final approval of manuscript	Conception and design	Conceived and designed the experiments	Conceptualization	YES
4457348	26137522	Luming Chen	1	Conception and design|Collection and assembly of data|Data analysis and interpretation|Manuscript writing|Final approval of manuscript	Collection and assembly of data	Performed the experiments	Investigation	YES
4457348	26137522	Luming Chen	1	Conception and design|Collection and assembly of data|Data analysis and interpretation|Manuscript writing|Final approval of manuscript	Data analysis and interpretation	Analyzed the data	Formal analysis	YES
4457348	26137522	Luming Chen	1	Conception and design|Collection and assembly of data|Data analysis and interpretation|Manuscript writing|Final approval of manuscript	Manuscript writing	Wrote the paper	Writing - Original Draft	YES
4457348	26137522	Luming Chen	1	Conception and design|Collection and assembly of data|Data analysis and interpretation|Manuscript writing|Final approval of manuscript	Final approval of manuscript	-	-	NO
4457348	26137522	Tiehua Chen	1	Conception and design|Collection and assembly of data|Data analysis and interpretation|Manuscript writing|Final approval of manuscript	Conception and design	Conceived and designed the experiments	Conceptualization	YES
4457348	26137522	Tiehua Chen	1	Conception and design|Collection and assembly of data|Data analysis and interpretation|Manuscript writing|Final approval of manuscript	Collection and assembly of data	Performed the experiments	Investigation	YES
4457348	26137522	Tiehua Chen	1	Conception and design|Collection and assembly of data|Data analysis and interpretation|Manuscript writing|Final approval of manuscript	Data analysis and interpretation	Analyzed the data	Formal analysis	YES
4457348	26137522	Tiehua Chen	1	Conception and design|Collection and assembly of data|Data analysis and interpretation|Manuscript writing|Final approval of manuscript	Manuscript writing	Wrote the paper	Writing - Original Draft	YES
4457348	26137522	Tiehua Chen	1	Conception and design|Collection and assembly of data|Data analysis and interpretation|Manuscript writing|Final approval of manuscript	Final approval of manuscript	-	-	NO
5122032	27881090	A-MW	2	participated in the design of the study and performed the statistical analysis|coordinated the research and wrote the manuscript	participated in the design of the study and performed the statistical analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5122032	27881090	A-MW	2	participated in the design of the study and performed the statistical analysis|coordinated the research and wrote the manuscript	coordinated the research and wrote the manuscript	Wrote the paper	Project administration|Writing - Original Draft	YES
5122032	27881090	BZ	2	carried out the chromsomal localization	carried out the chromsomal localization	Performed the experiments	Investigation	YES
5122032	27881090	JW	2	carried out the chromsomal localization	carried out the chromsomal localization	Performed the experiments	Investigation	YES
5122032	27881090	MK	2	carried out the molecular genetic analysis, localization and expression pattern studies, participated in the sequence alignment, bioinformatics analysis and drafted the manuscript|participated in the design of the study and performed the statistical analysis	carried out the molecular genetic analysis, localization and expression pattern studies, participated in the sequence alignment, bioinformatics analysis and drafted the manuscript	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5122032	27881090	MK	2	carried out the molecular genetic analysis, localization and expression pattern studies, participated in the sequence alignment, bioinformatics analysis and drafted the manuscript|participated in the design of the study and performed the statistical analysis	participated in the design of the study and performed the statistical analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5122032	27881090	PD	2	carried out the molecular genetic analysis, localization and expression pattern studies, participated in the sequence alignment, bioinformatics analysis and drafted the manuscript	carried out the molecular genetic analysis, localization and expression pattern studies, participated in the sequence alignment, bioinformatics analysis and drafted the manuscript	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5122032	27881090	QX	2	carried out the molecular genetic analysis, localization and expression pattern studies, participated in the sequence alignment, bioinformatics analysis and drafted the manuscript	carried out the molecular genetic analysis, localization and expression pattern studies, participated in the sequence alignment, bioinformatics analysis and drafted the manuscript	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5122032	27881090	SG	2	participated in the design of the study and performed the statistical analysis|coordinated the research and wrote the manuscript	participated in the design of the study and performed the statistical analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5122032	27881090	SG	2	participated in the design of the study and performed the statistical analysis|coordinated the research and wrote the manuscript	coordinated the research and wrote the manuscript	Wrote the paper	Project administration|Writing - Original Draft	YES
5122032	27881090	YW	2	participated in the design of the study and performed the statistical analysis|coordinated the research and wrote the manuscript	participated in the design of the study and performed the statistical analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5122032	27881090	YW	2	participated in the design of the study and performed the statistical analysis|coordinated the research and wrote the manuscript	coordinated the research and wrote the manuscript	Wrote the paper	Project administration|Writing - Original Draft	YES
5122032	27881090	YY	2	carried out the molecular genetic analysis, localization and expression pattern studies, participated in the sequence alignment, bioinformatics analysis and drafted the manuscript	carried out the molecular genetic analysis, localization and expression pattern studies, participated in the sequence alignment, bioinformatics analysis and drafted the manuscript	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4401714	25885920	A. Rauco	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401714	25885920	A. Russo	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401714	25885920	AC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401714	25885920	AF	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401714	25885920	AL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401714	25885920	CO	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401714	25885920	CP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401714	25885920	DM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401714	25885920	DS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401714	25885920	DS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401714	25885920	EV	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401714	25885920	FMG	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401714	25885920	FMG	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401714	25885920	FP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401714	25885920	FP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401714	25885920	FP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401714	25885920	FP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401714	25885920	GC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401714	25885920	GP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401714	25885920	GS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401714	25885920	GT	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401714	25885920	LG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401714	25885920	M. Santoni	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401714	25885920	M. Silletta	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401714	25885920	MM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401714	25885920	MR	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401714	25885920	PC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401714	25885920	RI	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401714	25885920	SC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401714	25885920	VB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5483480	28694816	LF	PLoS52	conceived the design of this research|performed the bioinformatics data analysis|wrote the paper	conceived the design of this research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5483480	28694816	LF	PLoS52	conceived the design of this research|performed the bioinformatics data analysis|wrote the paper	performed the bioinformatics data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5483480	28694816	LF	PLoS52	conceived the design of this research|performed the bioinformatics data analysis|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5483480	28694816	QZ	PLoS52	performed the bioinformatics data analysis|contributed to the revising of the manuscript	performed the bioinformatics data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5483480	28694816	QZ	PLoS52	performed the bioinformatics data analysis|contributed to the revising of the manuscript	contributed to the revising of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5483480	28694816	SP	PLoS52	conceived the design of this research	conceived the design of this research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5483480	28694816	WD	PLoS52	contributed to the revising of the manuscript	contributed to the revising of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5483480	28694816	YS	PLoS52	contributed to the revising of the manuscript	contributed to the revising of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5483480	28694816	ZP	PLoS52	conceived the design of this research|contributed to the statistical analyses and in the revising of the manuscript	conceived the design of this research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5483480	28694816	ZP	PLoS52	conceived the design of this research|contributed to the statistical analyses and in the revising of the manuscript	contributed to the statistical analyses and in the revising of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
3199744	21801426	ABS	2	has designed the experimental study and drafted the fluid collection protocol, collected human samples, carried out the majority of the experiments, and drafted the manuscript	has designed the experimental study and drafted the fluid collection protocol, collected human samples, carried out the majority of the experiments, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
3199744	21801426	AMC	2	have participated in the conception and design of the study, and data interpretation	have participated in the conception and design of the study, and data interpretation	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
3199744	21801426	KEB	2	participated in writing the fluid collection protocol and has made substantial contribution in performing the human samples collection	participated in writing the fluid collection protocol and has made substantial contribution in performing the human samples collection	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Methodology|Resources	YES
3199744	21801426	LC	2	has made significant contributions to the overall concept of the study, experimental design, data interpretation, and final revision of the manuscript	has made significant contributions to the overall concept of the study, experimental design, data interpretation, and final revision of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Resources|Writing - Review & Editing	YES
3199744	21801426	MS	2	method for protein detection in biological fluids	method for protein detection in biological fluids	Performed the experiments	Investigation	YES
3199744	21801426	PG	2	have participated in the conception and design of the study, and data interpretation	have participated in the conception and design of the study, and data interpretation	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
4450226	26090417	Abu Bakar Salleh	2	conceptualized and designed the experiments|contributed materials, reagents, and analysis tools	conceptualized and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4450226	26090417	Abu Bakar Salleh	2	conceptualized and designed the experiments|contributed materials, reagents, and analysis tools	contributed materials, reagents, and analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4450226	26090417	Raja Abd Rahman	2	contributed materials, reagents, and analysis tools	contributed materials, reagents, and analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4450226	26090417	Raja Noor Zaliha	2	contributed materials, reagents, and analysis tools	contributed materials, reagents, and analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4450226	26090417	Siti Nurbaya Oslan	2	contributed with the wrote the paper with	contributed with the wrote the paper with	Wrote the paper	Writing - Original Draft	YES
4450226	26090417	Sivasangkary Gandhi	2	conceptualized and designed the experiments|performed the experiments and analyzed the data|wrote the paper with	conceptualized and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4450226	26090417	Sivasangkary Gandhi	2	conceptualized and designed the experiments|performed the experiments and analyzed the data|wrote the paper with	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4450226	26090417	Sivasangkary Gandhi	2	conceptualized and designed the experiments|performed the experiments and analyzed the data|wrote the paper with	wrote the paper with	Wrote the paper	Writing - Original Draft	YES
4450226	26090417	Thean Chor Leow	2	contributed materials, reagents, and analysis tools	contributed materials, reagents, and analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
3204218	21978457	DMG	7	design, intellectual content, and editorial support	design, intellectual content, and editorial support	Conceived and designed the experiments|Wrote the paper	Writing - Review & Editing	YES
3204218	21978457	PCJ	7	conception and design, data collection and analysis, figure and manuscript preparation	conception and design, data collection and analysis, figure and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Visualization|Writing - Original Draft	YES
5122153	27881083	MF	2	collected cattle tissue samples and expression analysis	collected cattle tissue samples and expression analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5122153	27881083	SS	2	designed the study|performed the cnv analysis, gwas, molecular analysis, expression analysis|performed mouse experiments and pathological examinations|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5122153	27881083	SS	2	designed the study|performed the cnv analysis, gwas, molecular analysis, expression analysis|performed mouse experiments and pathological examinations|wrote the manuscript	performed the cnv analysis, gwas, molecular analysis, expression analysis	Performed the experiments	Investigation	YES
5122153	27881083	SS	2	designed the study|performed the cnv analysis, gwas, molecular analysis, expression analysis|performed mouse experiments and pathological examinations|wrote the manuscript	performed mouse experiments and pathological examinations	Performed the experiments	Investigation	YES
5122153	27881083	SS	2	designed the study|performed the cnv analysis, gwas, molecular analysis, expression analysis|performed mouse experiments and pathological examinations|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5122153	27881083	TA	2	collected cattle tissue samples and expression analysis	collected cattle tissue samples and expression analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5122153	27881083	TI	2	designed the study|collected and analyzed the data|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5122153	27881083	TI	2	designed the study|collected and analyzed the data|wrote the manuscript	collected and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5122153	27881083	TI	2	designed the study|collected and analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5122153	27881083	YS	2	performed mouse experiments and pathological examinations|wrote the manuscript	performed mouse experiments and pathological examinations	Performed the experiments	Investigation	YES
5122153	27881083	YS	2	performed mouse experiments and pathological examinations|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4401716	25884495	AH	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401716	25884495	AMC	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401716	25884495	ATW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401716	25884495	DK	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401716	25884495	DL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401716	25884495	EL	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401716	25884495	HA	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401716	25884495	MH	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401716	25884495	MP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401716	25884495	MP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401716	25884495	MP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401716	25884495	MP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401716	25884495	SB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401716	25884495	SFL	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401716	25884495	SFL	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401716	25884495	TJE	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401716	25884495	UE	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4457350	26137510	E.A.	2	designed the study, reviewed and edited the manuscript	designed the study, reviewed and edited the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
4457350	26137510	H.K.	2	reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
4457350	26137510	H.M.	2	contributed to the discussion	contributed to the discussion	-	-	NO
4457350	26137510	J.K.	2	contributed to the discussion	contributed to the discussion	-	-	NO
4457350	26137510	K.O.	2	researched data, and contributed to discussion	researched data, and contributed to discussion	Analyzed the data	Formal analysis	YES
4457350	26137510	M.A.S.	2	contributed to the discussion	contributed to the discussion	-	-	NO
4457350	26137510	M.I.	2	contributed to the discussion	contributed to the discussion	-	-	NO
4457350	26137510	R.G.	2	researched data	researched data	Analyzed the data	Formal analysis	YES
4457350	26137510	R.M.	2	researched data	researched data	Analyzed the data	Formal analysis	YES
4457350	26137510	S.Ka	2	contributed to the discussion	contributed to the discussion	-	-	NO
4457350	26137510	S.Ki	2	researched data, and contributed to discussion	researched data, and contributed to discussion	Analyzed the data	Formal analysis	YES
4457350	26137510	T.K.	2	designed the study, researched data, contributed to discussion and wrote the manuscript	designed the study, researched data, contributed to discussion and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4457350	26137510	T.M.	2	contributed to the discussion	contributed to the discussion	-	-	NO
5487388	28702044	All co-authors	2	commented on and approved the final manuscript draft	commented on and approved the final manuscript draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5487388	28702044	JH	2	together designed and executed the research project|conducted the spectral reflectance measurements|assisted with the lead the reflectance data analysis and drafted the manuscript with the	together designed and executed the research project	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5487388	28702044	JH	2	together designed and executed the research project|conducted the spectral reflectance measurements|assisted with the lead the reflectance data analysis and drafted the manuscript with the	conducted the spectral reflectance measurements	Performed the experiments	Investigation	YES
5487388	28702044	JH	2	together designed and executed the research project|conducted the spectral reflectance measurements|assisted with the lead the reflectance data analysis and drafted the manuscript with the	assisted with the lead the reflectance data analysis and drafted the manuscript with the	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5487388	28702044	MD	2	together designed and executed the research project|conducted the spectral reflectance measurements|lead the reflectance data analysis and drafted the manuscript with the	together designed and executed the research project	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5487388	28702044	MD	2	together designed and executed the research project|conducted the spectral reflectance measurements|lead the reflectance data analysis and drafted the manuscript with the	conducted the spectral reflectance measurements	Performed the experiments	Investigation	YES
5487388	28702044	MD	2	together designed and executed the research project|conducted the spectral reflectance measurements|lead the reflectance data analysis and drafted the manuscript with the	lead the reflectance data analysis and drafted the manuscript with the	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3210087	22018282	AC	2	generated the research ideas, secured funding and co-ordinated the research programme	generated the research ideas, secured funding and co-ordinated the research programme	Conceived and designed the experiments|Performed the experiments	Conceptualization|Funding acquisition|Investigation|Project administration	YES
3210087	22018282	BA	2	wrote the first draft of the paper and all authors contributed comments and suggestions to various draft versions|were responsible for study implementation	wrote the first draft of the paper and all authors contributed comments and suggestions to various draft versions	Wrote the paper	Writing - Original Draft	YES
3210087	22018282	BA	2	wrote the first draft of the paper and all authors contributed comments and suggestions to various draft versions|were responsible for study implementation	were responsible for study implementation	Performed the experiments	Investigation	YES
3210087	22018282	GN	2	managed the data|were responsible for study implementation	managed the data	Analyzed the data	Data curation	YES
3210087	22018282	GN	2	managed the data|were responsible for study implementation	were responsible for study implementation	Performed the experiments	Investigation	YES
3210087	22018282	HG	2	generated the research ideas, secured funding and co-ordinated the research programme	generated the research ideas, secured funding and co-ordinated the research programme	Conceived and designed the experiments|Performed the experiments	Conceptualization|Funding acquisition|Investigation|Project administration	YES
3210087	22018282	JB	2	were responsible for study implementation	were responsible for study implementation	Performed the experiments	Investigation	YES
3210087	22018282	SJ	2	wrote the first draft of the paper and all authors contributed comments and suggestions to various draft versions|generated the research ideas, secured funding and co-ordinated the research programme	wrote the first draft of the paper and all authors contributed comments and suggestions to various draft versions	Wrote the paper	Writing - Original Draft	YES
3210087	22018282	SJ	2	wrote the first draft of the paper and all authors contributed comments and suggestions to various draft versions|generated the research ideas, secured funding and co-ordinated the research programme	generated the research ideas, secured funding and co-ordinated the research programme	Conceived and designed the experiments|Performed the experiments	Conceptualization|Funding acquisition|Investigation|Project administration	YES
3968236	24400809	D.D.	2	contributed equally to this review	contributed equally to this review	-	-	NO
3968236	24400809	S.E.R.	2	contributed equally to this review	contributed equally to this review	-	-	NO
5122169	27881081	H. All	2	authors contributed to interpreting the data and to writing the manuscript	authors contributed to interpreting the data and to writing the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
5122169	27881081	JH	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5122169	27881081	PFS	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
3215651	21995490	AC	2	participated in design of the study	participated in design of the study	Conceived and designed the experiments	Methodology	YES
3215651	21995490	BN	2	participated in design of the study	participated in design of the study	Conceived and designed the experiments	Methodology	YES
3215651	21995490	GM	2	conceived and supervised the study	conceived and supervised the study	Conceived and designed the experiments	Conceptualization|Supervision	YES
3215651	21995490	JG	2	participated in design of the study	participated in design of the study	Conceived and designed the experiments	Methodology	YES
3215651	21995490	NF	2	participated in design of the study	participated in design of the study	Conceived and designed the experiments	Methodology	YES
3215651	21995490	ST	2	conceived and supervised the study	conceived and supervised the study	Conceived and designed the experiments	Conceptualization|Supervision	YES
3215651	21995490	VB	2	carried out the molecular biology work and subsequent analysis	carried out the molecular biology work and subsequent analysis	Performed the experiments	Investigation	YES
4401717	25885821	ACB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401717	25885821	ACB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401717	25885821	ACB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401717	25885821	ACB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401717	25885821	ALS	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401717	25885821	ALS	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401717	25885821	BHC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401717	25885821	BHC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401717	25885821	BHC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401717	25885821	BV	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401717	25885821	BV	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401717	25885821	CC	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401717	25885821	CC	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401717	25885821	GM	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401717	25885821	GM	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401717	25885821	GPP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401717	25885821	GPP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401717	25885821	GPP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401717	25885821	GPP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401717	25885821	GPP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401717	25885821	JSS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401717	25885821	JSS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401717	25885821	JSS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401717	25885821	KSP	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401717	25885821	KSP	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401717	25885821	KSP	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401717	25885821	MB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401717	25885821	MB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401717	25885821	MB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401717	25885821	MB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401717	25885821	MHM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401717	25885821	MHM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401717	25885821	MHM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401717	25885821	MLH	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401717	25885821	MLH	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401717	25885821	MLH	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401717	25885821	RM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401717	25885821	RM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401717	25885821	RM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401717	25885821	RM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401717	25885821	RS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401717	25885821	RS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401717	25885821	RS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401717	25885821	RS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401717	25885821	RS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401717	25885821	SC	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401717	25885821	SC	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401717	25885821	SHV	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401717	25885821	SHV	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401717	25885821	SHV	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401717	25885821	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401717	25885821	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401717	25885821	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401717	25885821	VM	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401717	25885821	VM	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401717	25885821	VVS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401717	25885821	VVS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401717	25885821	VVS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401717	25885821	VVS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401717	25885821	VVS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5487394	28702035	BT	2	analyzed the data and results	analyzed the data and results	Analyzed the data	Formal analysis	YES
5487394	28702035	DZ	2	analyzed the data and results	analyzed the data and results	Analyzed the data	Formal analysis	YES
5487394	28702035	HM	2	conceived, designed and conducted the experiments|monitored the experiments and critically commented on the manuscript	conceived, designed and conducted the experiments	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
5487394	28702035	HM	2	conceived, designed and conducted the experiments|monitored the experiments and critically commented on the manuscript	monitored the experiments and critically commented on the manuscript	-	Supervision	YES
5487394	28702035	HS	2	conceived, designed and conducted the experiments|monitored the experiments and critically commented on the manuscript	conceived, designed and conducted the experiments	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
5487394	28702035	HS	2	conceived, designed and conducted the experiments|monitored the experiments and critically commented on the manuscript	monitored the experiments and critically commented on the manuscript	-	Supervision	YES
5487394	28702035	LX	2	analyzed the data and results	analyzed the data and results	Analyzed the data	Formal analysis	YES
5487394	28702035	XH	2	analyzed the data and results	analyzed the data and results	Analyzed the data	Formal analysis	YES
5487394	28702035	XL	2	conceived, designed and conducted the experiments	conceived, designed and conducted the experiments	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
5487394	28702035	YH	2	analyzed the data and results	analyzed the data and results	Analyzed the data	Formal analysis	YES
5487394	28702035	ZX	2	conceived, designed and conducted the experiments|wrote the manuscript	conceived, designed and conducted the experiments	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
5487394	28702035	ZX	2	conceived, designed and conducted the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4457352	26125048	A.E.S.	2	designed and supervised the clinical study	designed and supervised the clinical study	Conceived and designed the experiments	Methodology|Supervision	YES
4457352	26125048	D.J.S.	2	performed the in vivo experiments|analyzed data	performed the in vivo experiments	Performed the experiments	Investigation	YES
4457352	26125048	D.J.S.	2	performed the in vivo experiments|analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
4457352	26125048	G.C.H.	2	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
4457352	26125048	H.M.	2	performed in situ hybridization for ptgs2	performed in situ hybridization for ptgs2	Performed the experiments	Investigation	YES
4457352	26125048	J.M.B.	2	performed the in vivo experiments|extracted rna and performed qrt pcr|analyzed data	performed the in vivo experiments	Performed the experiments	Investigation	YES
4457352	26125048	J.M.B.	2	performed the in vivo experiments|extracted rna and performed qrt pcr|analyzed data	extracted rna and performed qrt pcr	Performed the experiments	Investigation	YES
4457352	26125048	J.M.B.	2	performed the in vivo experiments|extracted rna and performed qrt pcr|analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
4457352	26125048	M.C.	2	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
4457352	26125048	M.M.	2	provided the anti-ccr2 monoclonal antibody	provided the anti-ccr2 monoclonal antibody	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4457352	26125048	P.L.R.	2	performed the statistical analysis of the clinical data	performed the statistical analysis of the clinical data	Analyzed the data	Formal analysis	YES
4457352	26125048	PBS	2	encapsulated liposomes	encapsulated liposomes	-	-	NO
4457352	26125048	S.J.H.	2	designed the experiments|wrote the manuscript incorporating all of the authors editorial input	designed the experiments	Conceived and designed the experiments	Methodology	YES
4457352	26125048	S.J.H.	2	designed the experiments|wrote the manuscript incorporating all of the authors editorial input	wrote the manuscript incorporating all of the authors editorial input	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4457352	26125048	T.E.R.	2	performed immunofluorescence microscopy	performed immunofluorescence microscopy	Performed the experiments	Investigation	YES
4457352	26125048	T.J.H.	2	designed the experiments|performed the in vivo experiments|extracted rna and performed qrt pcr|performed histopathological analysis|performed immunofluorescence microscopy|wrote the manuscript incorporating all of the authors editorial input	designed the experiments	Conceived and designed the experiments	Methodology	YES
4457352	26125048	T.J.H.	2	designed the experiments|performed the in vivo experiments|extracted rna and performed qrt pcr|performed histopathological analysis|performed immunofluorescence microscopy|wrote the manuscript incorporating all of the authors editorial input	performed the in vivo experiments	Performed the experiments	Investigation	YES
4457352	26125048	T.J.H.	2	designed the experiments|performed the in vivo experiments|extracted rna and performed qrt pcr|performed histopathological analysis|performed immunofluorescence microscopy|wrote the manuscript incorporating all of the authors editorial input	extracted rna and performed qrt pcr	Performed the experiments	Investigation	YES
4457352	26125048	T.J.H.	2	designed the experiments|performed the in vivo experiments|extracted rna and performed qrt pcr|performed histopathological analysis|performed immunofluorescence microscopy|wrote the manuscript incorporating all of the authors editorial input	performed histopathological analysis	Performed the experiments	Investigation	YES
4457352	26125048	T.J.H.	2	designed the experiments|performed the in vivo experiments|extracted rna and performed qrt pcr|performed histopathological analysis|performed immunofluorescence microscopy|wrote the manuscript incorporating all of the authors editorial input	performed immunofluorescence microscopy	Performed the experiments	Investigation	YES
4457352	26125048	T.J.H.	2	designed the experiments|performed the in vivo experiments|extracted rna and performed qrt pcr|performed histopathological analysis|performed immunofluorescence microscopy|wrote the manuscript incorporating all of the authors editorial input	wrote the manuscript incorporating all of the authors editorial input	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4457352	26125048	T.M.H.	2	designed and supervised the clinical study	designed and supervised the clinical study	Conceived and designed the experiments	Methodology|Supervision	YES
4457352	26125048	T.S.S.	2	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
4457352	26125048	W.F.S.	2	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5549244	28240888	All authors	2	have given approval to the final version of the manuscript	have given approval to the final version of the manuscript	-	-	NO
5549244	28240888	The authors	2	contributed equally	contributed equally	-	-	NO
5045944	27713829	K. A. Shibany	1	Participated in research design|Conducted experiments|Performed data analysis|Contributed to writing manuscript	Participated in research design	Conceived and designed the experiments	-	YES
5045944	27713829	K. A. Shibany	1	Participated in research design|Conducted experiments|Performed data analysis|Contributed to writing manuscript	Conducted experiments	Performed the experiments	Investigation	YES
5045944	27713829	K. A. Shibany	1	Participated in research design|Conducted experiments|Performed data analysis|Contributed to writing manuscript	Performed data analysis	Analyzed the data	Formal analysis	YES
5045944	27713829	K. A. Shibany	1	Participated in research design|Conducted experiments|Performed data analysis|Contributed to writing manuscript	Contributed to writing manuscript	Wrote the paper	Writing - Original Draft	YES
5045944	27713829	S. L. Pratt	1	Participated in research design|Conducted experiments|Performed data analysis|Contributed to writing manuscript	Participated in research design	Conceived and designed the experiments	-	YES
5045944	27713829	S. L. Pratt	1	Participated in research design|Conducted experiments|Performed data analysis|Contributed to writing manuscript	Conducted experiments	Performed the experiments	Investigation	YES
5045944	27713829	S. L. Pratt	1	Participated in research design|Conducted experiments|Performed data analysis|Contributed to writing manuscript	Performed data analysis	Analyzed the data	Formal analysis	YES
5045944	27713829	S. L. Pratt	1	Participated in research design|Conducted experiments|Performed data analysis|Contributed to writing manuscript	Contributed to writing manuscript	Wrote the paper	Writing - Original Draft	YES
5045944	27713829	S. Totemeyer	1	Participated in research design|Contributed to writing manuscript	Participated in research design	Conceived and designed the experiments	-	YES
5045944	27713829	S. Totemeyer	1	Participated in research design|Contributed to writing manuscript	Contributed to writing manuscript	Wrote the paper	Writing - Original Draft	YES
5045944	27713829	S. W. Paine	1	Participated in research design|Contributed to writing manuscript	Participated in research design	Conceived and designed the experiments	-	YES
5045944	27713829	S. W. Paine	1	Participated in research design|Contributed to writing manuscript	Contributed to writing manuscript	Wrote the paper	Writing - Original Draft	YES
5122201	27881087	RWM	PLoS52	wrote the paper|finalized the manuscript	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5122201	27881087	RWM	PLoS52	wrote the paper|finalized the manuscript	finalized the manuscript	Wrote the paper	Writing - Review & Editing	YES
5122201	27881087	XZ	PLoS52	wrote the paper|finalized the manuscript	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5122201	27881087	XZ	PLoS52	wrote the paper|finalized the manuscript	finalized the manuscript	Wrote the paper	Writing - Review & Editing	YES
5122201	27881087	YX	PLoS52	carried out molecular lab work and conceived the project and analyzed the data|wrote the paper	carried out molecular lab work and conceived the project and analyzed the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation	YES
5122201	27881087	YX	PLoS52	carried out molecular lab work and conceived the project and analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5122201	27881087	YZ	PLoS52	wrote the perl script	wrote the perl script	Contributed reagents/materials/analysis tools|Wrote the paper	Software|Writing - Original Draft	YES
3215920	22026962	CPa	2	designed the study, collected data, reviewed and commented draft of manuscript before submission	designed the study, collected data, reviewed and commented draft of manuscript before submission	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
3215920	22026962	CPh	2	collected data, reviewed and commented draft of manuscript before submission	collected data, reviewed and commented draft of manuscript before submission	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
3215920	22026962	JA	2	designed the study, collected data, wrote the first draft, reviewed and commented draft of manuscript before submission	designed the study, collected data, wrote the first draft, reviewed and commented draft of manuscript before submission	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
3215920	22026962	KR	2	designed the study, collected data, reviewed and commented draft of manuscript before submission	designed the study, collected data, reviewed and commented draft of manuscript before submission	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
3215920	22026962	PB	2	analyzed, reviewed and commented draft of manuscript before submission	analyzed, reviewed and commented draft of manuscript before submission	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
3215920	22026962	PK	2	designed the study, collected data, wrote the first draft, reviewed and commented draft of manuscript before submission	designed the study, collected data, wrote the first draft, reviewed and commented draft of manuscript before submission	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
3215920	22026962	PL	2	designed the study, collected data, reviewed and commented draft of manuscript before submission	designed the study, collected data, reviewed and commented draft of manuscript before submission	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
3215920	22026962	SK	2	analyzed, reviewed and commented draft of manuscript before submission	analyzed, reviewed and commented draft of manuscript before submission	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
3215920	22026962	TB	2	designed the study, collected data, wrote the first draft, reviewed and commented draft of manuscript before submission	designed the study, collected data, wrote the first draft, reviewed and commented draft of manuscript before submission	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
3215920	22026962	TM	2	collected data, reviewed and commented draft of manuscript before submission	collected data, reviewed and commented draft of manuscript before submission	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
3215920	22026962	TP	2	designed the study, collected data, wrote the first draft, reviewed and commented draft of manuscript before submission	designed the study, collected data, wrote the first draft, reviewed and commented draft of manuscript before submission	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
3215920	22026962	WP	2	designed the study, collected data, reviewed and commented draft of manuscript before submission	designed the study, collected data, reviewed and commented draft of manuscript before submission	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
3220628	21992146	All authors	2	contributed to design of the study	contributed to design of the study	Conceived and designed the experiments	Methodology	YES
3220628	21992146	BW	2	performed the statistical analysis|helped to draft the initial manuscript	performed the statistical analysis	Analyzed the data	Formal analysis	YES
3220628	21992146	BW	2	performed the statistical analysis|helped to draft the initial manuscript	helped to draft the initial manuscript	Wrote the paper	Writing - Original Draft	YES
3220628	21992146	JGJ	2	coordinated data collection	coordinated data collection	Performed the experiments	Investigation|Project administration	YES
3220628	21992146	KAC	2	helped to draft the initial manuscript	helped to draft the initial manuscript	Wrote the paper	Writing - Original Draft	YES
3220628	21992146	LCI	2	coordinated data collection|helped to draft the initial manuscript	coordinated data collection	Performed the experiments	Investigation|Project administration	YES
3220628	21992146	LCI	2	coordinated data collection|helped to draft the initial manuscript	helped to draft the initial manuscript	Wrote the paper	Writing - Original Draft	YES
3220628	21992146	MSF	2	performed the statistical analysis|helped to draft the initial manuscript	performed the statistical analysis	Analyzed the data	Formal analysis	YES
3220628	21992146	MSF	2	performed the statistical analysis|helped to draft the initial manuscript	helped to draft the initial manuscript	Wrote the paper	Writing - Original Draft	YES
3220628	21992146	SCA	2	coordinated data collection	coordinated data collection	Performed the experiments	Investigation|Project administration	YES
4401718	25885410	BE	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401718	25885410	BE	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401718	25885410	BE	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401718	25885410	DZ	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401718	25885410	DZ	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401718	25885410	JB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401718	25885410	JB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401718	25885410	JB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401718	25885410	NZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401718	25885410	NZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401718	25885410	NZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401718	25885410	NZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401718	25885410	NZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401718	25885410	YN	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401718	25885410	YN	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401718	25885410	YN	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5114692	27891230	All authors	2	contributed to the analysis and interpretation of the data, and to the drafting of the manuscript	contributed to the analysis and interpretation of the data, and to the drafting of the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
5114692	27891230	EvS	2	were the primary authors involved in model development	were the primary authors involved in model development	Performed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5114692	27891230	MM	2	were the primary authors involved in model development	were the primary authors involved in model development	Performed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5487432	28702036	BL	2	designed the experiments and analyzed the data	designed the experiments and analyzed the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5487432	28702036	JL	2	provided technical assistance	provided technical assistance	Performed the experiments	Investigation	YES
5487432	28702036	LW	2	provided assistance with some of the experiments	provided assistance with some of the experiments	Performed the experiments	Investigation	YES
5487432	28702036	MJ	2	performed most of the experiments	performed most of the experiments	Performed the experiments	Investigation	YES
5487432	28702036	ND	2	provided assistance with some of the experiments	provided assistance with some of the experiments	Performed the experiments	Investigation	YES
5487432	28702036	PD	2	provided technical assistance	provided technical assistance	Performed the experiments	Investigation	YES
5487432	28702036	QZ	2	provided assistance with some of the experiments	provided assistance with some of the experiments	Performed the experiments	Investigation	YES
5487432	28702036	SX	2	provided assistance with some of the experiments	provided assistance with some of the experiments	Performed the experiments	Investigation	YES
5487432	28702036	WJ	2	conceived the project, supervised the experiments, and complemented the writing	conceived the project, supervised the experiments, and complemented the writing	Conceived and designed the experiments|Wrote the paper	Conceptualization|Supervision	YES
5487432	28702036	WM	2	provided technical assistance	provided technical assistance	Performed the experiments	Investigation	YES
5487432	28702036	YZ	2	provided technical assistance	provided technical assistance	Performed the experiments	Investigation	YES
512281	15268766	CES	2	designed and carried out the patient analysis	designed and carried out the patient analysis	Conceived and designed the experiments|Performed the experiments	Investigation	YES
512281	15268766	DBE	2	designed and carried out the patient analysis	designed and carried out the patient analysis	Conceived and designed the experiments|Performed the experiments	Investigation	YES
512281	15268766	MM	2	provided clones	provided clones	Contributed reagents/materials/analysis tools	Resources	YES
512281	15268766	MMN	2	provided the sd1 patient material	provided the sd1 patient material	Contributed reagents/materials/analysis tools	Resources	YES
512281	15268766	PGZ	2	contributed to the experimental design and subcloning	contributed to the experimental design and subcloning	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
512281	15268766	RCB	2	provided the sd1 patient material	provided the sd1 patient material	Contributed reagents/materials/analysis tools	Resources	YES
512281	15268766	RT	2	contributed to the experimental design	contributed to the experimental design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
512281	15268766	TO	2	contributed to the experimental design	contributed to the experimental design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3223494	22047185	AB	2	reviewed literature, and helped in interpreting data and writing the manuscript	reviewed literature, and helped in interpreting data and writing the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
3223494	22047185	AKR	2	conducted laboratory tests for nevirapine levels	conducted laboratory tests for nevirapine levels	Performed the experiments	Investigation	YES
3223494	22047185	HA	2	conducted laboratory tests for cd4 cell count and plasma viral load	conducted laboratory tests for cd4 cell count and plasma viral load	Performed the experiments	Investigation	YES
3223494	22047185	JCS	2	conducted laboratory tests for cd4 cell count and plasma viral load	conducted laboratory tests for cd4 cell count and plasma viral load	Performed the experiments	Investigation	YES
3223494	22047185	KC	2	reviewed literature, and helped in interpreting data and writing the manuscript	reviewed literature, and helped in interpreting data and writing the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
3223494	22047185	ME	2	reviewed literature, and helped in interpreting data and writing the manuscript	reviewed literature, and helped in interpreting data and writing the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
3223494	22047185	NB	2	reviewed literature, and helped in interpreting data and writing the manuscript	reviewed literature, and helped in interpreting data and writing the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
3223494	22047185	NK	2	conducted laboratory tests for cd4 cell count and plasma viral load	conducted laboratory tests for cd4 cell count and plasma viral load	Performed the experiments	Investigation	YES
3223494	22047185	NS	2	reviewed literature, and helped in interpreting data and writing the manuscript	reviewed literature, and helped in interpreting data and writing the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
3223494	22047185	RCS	2	reviewed literature, and helped in interpreting data and writing the manuscript	reviewed literature, and helped in interpreting data and writing the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
3223494	22047185	RLM	2	edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
3223494	22047185	SD	2	reviewed literature, and helped in interpreting data and writing the manuscript	reviewed literature, and helped in interpreting data and writing the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
3223494	22047185	SK	2	conducted laboratory tests for nevirapine levels	conducted laboratory tests for nevirapine levels	Performed the experiments	Investigation	YES
3223494	22047185	SKS	2	reviewed literature, and helped in interpreting data and writing the manuscript	reviewed literature, and helped in interpreting data and writing the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
3223494	22047185	SS	2	provided inputs to the study design, helped in data analysis and interpretation, wrote the manuscript, and did final editing	provided inputs to the study design, helped in data analysis and interpretation, wrote the manuscript, and did final editing	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
3223494	22047185	TV	2	conducted laboratory tests for nevirapine levels	conducted laboratory tests for nevirapine levels	Performed the experiments	Investigation	YES
3223494	22047185	VS	2	did data analysis	did data analysis	Analyzed the data	Formal analysis	YES
3417176	22919314	Yang-Dong Wang	2	contribute equally to the paper	contribute equally to the paper	-	-	NO
3417176	22919314	Yi-Cun Chen	2	contribute equally to the paper	contribute equally to the paper	-	-	NO
3238297	22060823	KS	2	revised manuscript critically for important intellectual content	revised manuscript critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
3238297	22060823	NK	2	participated in data collection, performed the statistical analysis, and drafted the manuscript	participated in data collection, performed the statistical analysis, and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3238297	22060823	RC	2	participated in the design of the study, performed the statistical analysis, and drafted the manuscript	participated in the design of the study, performed the statistical analysis, and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3238297	22060823	TS	2	revised manuscript critically for important intellectual content	revised manuscript critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4401719	25886169	BYX	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401719	25886169	BYX	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401719	25886169	CHJ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401719	25886169	HXM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401719	25886169	JHL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401719	25886169	JHL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401719	25886169	JHL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401719	25886169	JHL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401719	25886169	Jianbin Zhang	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401719	25886169	Jing Zhang	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401719	25886169	Jing Zhang	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401719	25886169	Jing Zhang	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401719	25886169	WH	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401719	25886169	ZQJ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401719	25886169	ZQJ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401719	25886169	ZW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5487440	28702037	AY	2	performed the plant growth trials and sample preparation|analyzed the data and drafted the manuscript	performed the plant growth trials and sample preparation	Performed the experiments	Investigation	YES
5487440	28702037	AY	2	performed the plant growth trials and sample preparation|analyzed the data and drafted the manuscript	analyzed the data and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5487440	28702037	All authors	2	edited the manuscript and approved the final manuscript	edited the manuscript and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5487440	28702037	EG	2	analyzed the data and drafted the manuscript	analyzed the data and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5487440	28702037	FP	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5487440	28702037	ML	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5487440	28702037	NB	2	analyzed the data and drafted the manuscript	analyzed the data and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5487440	28702037	SJ	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
512282	15283859	BHFW	2	was involved in all aspects of data assembly and prepared the manuscript	was involved in all aspects of data assembly and prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
512282	15283859	JK	2	carried out the statistical analyses and helped with the computational handling of data	carried out the statistical analyses and helped with the computational handling of data	Analyzed the data	Formal analysis	YES
512282	15283859	TG	2	conceptually developed the retinacentral database and is involved in the curation of the site	conceptually developed the retinacentral database and is involved in the curation of the site	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Data curation|Software	YES
4450232	26090392	All authors	2	read and approved the final paper	read and approved the final paper	-	-	NO
4450232	26090392	Danian Qin	2	conceived the study and helped to draft the paper	conceived the study and helped to draft the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4450232	26090392	Hanwei Wu	2	performed the qpcr	performed the qpcr	Performed the experiments	Investigation	YES
4450232	26090392	Lisha Mou	2	performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
4450232	26090392	Qiaoxia Zhang	2	performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
4450232	26090392	Ting Long	2	carried out the sirna transfection	carried out the sirna transfection	Performed the experiments	Investigation	YES
4450232	26090392	Weiren Huang	2	contributed equally to this work	contributed equally to this work	-	-	NO
4450232	26090392	Yaoting Gui	2	conceived the study and helped to draft the paper	conceived the study and helped to draft the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4450232	26090392	Yuanbin Chen	2	performed the mtt assays|contributed equally to this work	performed the mtt assays	Performed the experiments	Investigation	YES
4450232	26090392	Yuanbin Chen	2	performed the mtt assays|contributed equally to this work	contributed equally to this work	-	-	NO
4450232	26090392	Yuchen Liu	2	contributed equally to this work	contributed equally to this work	-	-	NO
4450232	26090392	Zhou Yu	2	carried out the western blot analysis	carried out the western blot analysis	Performed the experiments	Investigation	YES
3247823	22141425	All authors	2	contributed to the final report and approved the final manuscript	contributed to the final report and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
3247823	22141425	GGM	2	supervised and guided the student	supervised and guided the student	-	Supervision	YES
3247823	22141425	SNW	2	conceived, designed and conducted study, analysed data and interpreted findings	conceived, designed and conducted study, analysed data and interpreted findings	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation|Methodology	YES
3247823	22141425	ZWN	2	supervised and guided the student	supervised and guided the student	-	Supervision	YES
4401720	25886353	AET	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4401720	25886353	AET	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401720	25886353	BGH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401720	25886353	CH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401720	25886353	CSS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401720	25886353	CSS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401720	25886353	G. Wang	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401720	25886353	G. Wang	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401720	25886353	G. Want	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401720	25886353	G. Wolff	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4401720	25886353	G. Wolff	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401720	25886353	HB	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401720	25886353	HH	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4401720	25886353	HH	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401720	25886353	JA	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401720	25886353	JGM	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401720	25886353	JS	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401720	25886353	JSF	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401720	25886353	JSF	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401720	25886353	JYL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401720	25886353	MrS	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401720	25886353	RGC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401720	25886353	RGC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401720	25886353	RGC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401720	25886353	RJK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401720	25886353	RW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401720	25886353	RW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401720	25886353	RW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401720	25886353	SGP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4401720	25886353	SGP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401720	25886353	SS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4401720	25886353	SS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401720	25886353	SV	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401720	25886353	YSB	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401720	25886353	YSB	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3264517	22185294	AFF	2	conceived the study|participated in the study design, in the statistical analysis and in writing the result and coordination	conceived the study	Conceived and designed the experiments	Conceptualization	YES
3264517	22185294	AFF	2	conceived the study|participated in the study design, in the statistical analysis and in writing the result and coordination	participated in the study design, in the statistical analysis and in writing the result and coordination	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Project administration	YES
3264517	22185294	All authors	2	contributed to the discussion, proofread and approved the final manuscript	contributed to the discussion, proofread and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
3264517	22185294	BOA	2	participated in the study design and in writing the result	participated in the study design and in writing the result	Conceived and designed the experiments|Wrote the paper	Methodology	YES
3264517	22185294	EAB	2	participated in drafting the introduction	participated in drafting the introduction	Wrote the paper	Writing - Original Draft	YES
3264517	22185294	JOA	2	conceived the study|participated in drafting the introduction, in the study design and in the statistical analysis	conceived the study	Conceived and designed the experiments	Conceptualization	YES
3264517	22185294	JOA	2	conceived the study|participated in drafting the introduction, in the study design and in the statistical analysis	participated in drafting the introduction, in the study design and in the statistical analysis	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4457407	26137509	Swedish Government	1	Funding	Funding	-	Funding acquisition	YES
512283	15294027	JT	2	carried out the array fabrication and gene expression studies	carried out the array fabrication and gene expression studies	Performed the experiments	Investigation	YES
512283	15294027	LM	2	carried out the array fabrication and gene expression studies	carried out the array fabrication and gene expression studies	Performed the experiments	Investigation	YES
512283	15294027	MJH	2	conceived of the study, its design and coordination, and drafted the manuscript	conceived of the study, its design and coordination, and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
512283	15294027	SM	2	carried out the array fabrication and gene expression studies	carried out the array fabrication and gene expression studies	Performed the experiments	Investigation	YES
512283	15294027	XW	2	conceived of the study, its design and coordination, and drafted the manuscript|performed the statistical analysis	conceived of the study, its design and coordination, and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
512283	15294027	XW	2	conceived of the study, its design and coordination, and drafted the manuscript|performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
5487443	28702047	HL	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5487443	28702047	JJ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5487443	28702047	JX	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5487443	28702047	JY	PLoS52	conceived the study|designed the experiments|analyzed the data|wrote the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5487443	28702047	JY	PLoS52	conceived the study|designed the experiments|analyzed the data|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5487443	28702047	JY	PLoS52	conceived the study|designed the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5487443	28702047	JY	PLoS52	conceived the study|designed the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5487443	28702047	SZ	PLoS52	conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5487443	28702047	WC	PLoS52	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5487443	28702047	WF	PLoS52	performed the experiments|analyzed the data|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5487443	28702047	WF	PLoS52	performed the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5487443	28702047	WF	PLoS52	performed the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
2720517	19657462	BN	7	Data analysis and manuscript preparation	Data analysis and manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
2720517	19657462	PSVP	7	Data analysis and manuscript preparation	Data analysis and manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
2720517	19657462	TT	7	First author, initiation of project, data analysis and manuscript preparation	First author, initiation of project, data analysis and manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3884796	24711762	AAA	2	provided assistance in the study design and the write up	provided assistance in the study design and the write up	Conceived and designed the experiments|Wrote the paper	Methodology	YES
3884796	24711762	ASA	2	provided assistance in the design of the study, performed the laboratory measurement of biochemical parameters and also prepared the manuscript	provided assistance in the design of the study, performed the laboratory measurement of biochemical parameters and also prepared the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
3884796	24711762	DAA	2	carried out the design and coordinated the study, participated in most of the experiments	carried out the design and coordinated the study, participated in most of the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Project administration	YES
3884796	24711762	DPO	2	provided assistance in the design of the study, coordinated and carried out all the experiments	provided assistance in the design of the study, coordinated and carried out all the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Project administration	YES
3269361	22233928	AMC	2	oversaw quality assurance and laboratory management for hiv data	oversaw quality assurance and laboratory management for hiv data	Performed the experiments|Analyzed the data	Data curation|Supervision|Validation	YES
3269361	22233928	CC	2	managed the study and implemented the study protocol	managed the study and implemented the study protocol	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Project administration	YES
3269361	22233928	DW	2	conducted interviews and performed quality assurance for interview data	conducted interviews and performed quality assurance for interview data	Performed the experiments	Investigation|Validation	YES
3269361	22233928	MD	2	performed laboratory analyses hiv data	performed laboratory analyses hiv data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3269361	22233928	MJ	2	conducted interviews and performed quality assurance for interview data	conducted interviews and performed quality assurance for interview data	Performed the experiments	Investigation|Validation	YES
3269361	22233928	MOK	2	implemented the study protocol, managed the pill count data, and contributed to the study design	implemented the study protocol, managed the pill count data, and contributed to the study design	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Data curation|Investigation|Methodology|Project administration	YES
3269361	22233928	RFS	2	oversaw quality assurance and laboratory management of hiv data and contributed to the overall conceptualization of the study	oversaw quality assurance and laboratory management of hiv data and contributed to the overall conceptualization of the study	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Data curation|Investigation|Project administration|Supervision|Validation	YES
3269361	22233928	SCK	2	conceptualized the study, contributed to the data analyses, and prepared the manuscript	conceptualized the study, contributed to the data analyses, and prepared the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
4401721	25884623	CK	PLoS5	Aire instrument|Reviewing manuscript	Aire instrument	-	-	NO
4401721	25884623	CK	PLoS5	Aire instrument|Reviewing manuscript	Reviewing manuscript	Wrote the paper	Writing - Review & Editing	YES
4401721	25884623	EN	PLoS5	Aire instrument|Reviewing manuscript	Aire instrument	-	-	NO
4401721	25884623	EN	PLoS5	Aire instrument|Reviewing manuscript	Reviewing manuscript	Wrote the paper	Writing - Review & Editing	YES
4401721	25884623	HV	PLoS5	Conceived and designed the experiments|Literature selection and data extraction|Aire instrument|Selection of indicators|Reviewing manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401721	25884623	HV	PLoS5	Conceived and designed the experiments|Literature selection and data extraction|Aire instrument|Selection of indicators|Reviewing manuscript	Literature selection and data extraction	Analyzed the data	Data curation	YES
4401721	25884623	HV	PLoS5	Conceived and designed the experiments|Literature selection and data extraction|Aire instrument|Selection of indicators|Reviewing manuscript	Aire instrument	-	-	NO
4401721	25884623	HV	PLoS5	Conceived and designed the experiments|Literature selection and data extraction|Aire instrument|Selection of indicators|Reviewing manuscript	Selection of indicators	-	-	NO
4401721	25884623	HV	PLoS5	Conceived and designed the experiments|Literature selection and data extraction|Aire instrument|Selection of indicators|Reviewing manuscript	Reviewing manuscript	Wrote the paper	Writing - Review & Editing	YES
4401721	25884623	JM	PLoS5	Aire instrument|Reviewing manuscript	Aire instrument	-	-	NO
4401721	25884623	JM	PLoS5	Aire instrument|Reviewing manuscript	Reviewing manuscript	Wrote the paper	Writing - Review & Editing	YES
4401721	25884623	LV	PLoS5	Conceived and designed the experiments|Literature selection and data extraction|Aire instrument|Selection of indicators|Reviewing manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401721	25884623	LV	PLoS5	Conceived and designed the experiments|Literature selection and data extraction|Aire instrument|Selection of indicators|Reviewing manuscript	Literature selection and data extraction	Analyzed the data	Data curation	YES
4401721	25884623	LV	PLoS5	Conceived and designed the experiments|Literature selection and data extraction|Aire instrument|Selection of indicators|Reviewing manuscript	Aire instrument	-	-	NO
4401721	25884623	LV	PLoS5	Conceived and designed the experiments|Literature selection and data extraction|Aire instrument|Selection of indicators|Reviewing manuscript	Selection of indicators	-	-	NO
4401721	25884623	LV	PLoS5	Conceived and designed the experiments|Literature selection and data extraction|Aire instrument|Selection of indicators|Reviewing manuscript	Reviewing manuscript	Wrote the paper	Writing - Review & Editing	YES
4401721	25884623	MB	PLoS5	Aire instrument|Reviewing manuscript	Aire instrument	-	-	NO
4401721	25884623	MB	PLoS5	Aire instrument|Reviewing manuscript	Reviewing manuscript	Wrote the paper	Writing - Review & Editing	YES
4401721	25884623	MS	PLoS5	Conceived and designed the experiments|Wrote the paper|Literature selection and data extraction|Aire instrument|Selection of indicators	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401721	25884623	MS	PLoS5	Conceived and designed the experiments|Wrote the paper|Literature selection and data extraction|Aire instrument|Selection of indicators	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401721	25884623	MS	PLoS5	Conceived and designed the experiments|Wrote the paper|Literature selection and data extraction|Aire instrument|Selection of indicators	Literature selection and data extraction	Analyzed the data	Data curation	YES
4401721	25884623	MS	PLoS5	Conceived and designed the experiments|Wrote the paper|Literature selection and data extraction|Aire instrument|Selection of indicators	Aire instrument	-	-	NO
4401721	25884623	MS	PLoS5	Conceived and designed the experiments|Wrote the paper|Literature selection and data extraction|Aire instrument|Selection of indicators	Selection of indicators	-	-	NO
4457408	26137521	DPHN	PLoS5	Designed the study|Collected the patients samples	Designed the study	Conceived and designed the experiments	Methodology	YES
4457408	26137521	DPHN	PLoS5	Designed the study|Collected the patients samples	Collected the patients samples	Performed the experiments	Investigation	YES
4457408	26137521	KA	PLoS5	Designed the study|Performed the literature search, the comprehensive final data analysis and the data interpretation|Wrote the paper	Designed the study	Conceived and designed the experiments	Methodology	YES
4457408	26137521	KA	PLoS5	Designed the study|Performed the literature search, the comprehensive final data analysis and the data interpretation|Wrote the paper	Performed the literature search, the comprehensive final data analysis and the data interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4457408	26137521	KA	PLoS5	Designed the study|Performed the literature search, the comprehensive final data analysis and the data interpretation|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4457408	26137521	KHT	PLoS5	Collected the patients samples	Collected the patients samples	Performed the experiments	Investigation	YES
4457408	26137521	KNHM	PLoS5	Collected the patients samples|Analyzed the clinical data	Collected the patients samples	Performed the experiments	Investigation	YES
4457408	26137521	KNHM	PLoS5	Collected the patients samples|Analyzed the clinical data	Analyzed the clinical data	Analyzed the data	Formal analysis	YES
4457408	26137521	LVH	PLoS5	Performed the experiments and the data collection	Performed the experiments and the data collection	Performed the experiments	Investigation	YES
4457408	26137521	THTP	PLoS5	Performed the experiments and the data collection	Performed the experiments and the data collection	Performed the experiments	Investigation	YES
4457408	26137521	VHP	PLoS5	Designed the study|Performed the experiments and the data collection	Designed the study	Conceived and designed the experiments	Methodology	YES
4457408	26137521	VHP	PLoS5	Designed the study|Performed the experiments and the data collection	Performed the experiments and the data collection	Performed the experiments	Investigation	YES
5123246	28185554	AM	2	formulated the problem|developed this novel mathematical approach|designed this computational tool and the mysql relational database|implemented this computational tool in matlab|selected and extracted the data sets from the public databases, pre-process and loaded them into our mysql database|loaded the datasets into matlab|conducted the interpretation of the results|contributed equally to the writing of this manuscript	formulated the problem	Conceived and designed the experiments	Conceptualization	YES
5123246	28185554	AM	2	formulated the problem|developed this novel mathematical approach|designed this computational tool and the mysql relational database|implemented this computational tool in matlab|selected and extracted the data sets from the public databases, pre-process and loaded them into our mysql database|loaded the datasets into matlab|conducted the interpretation of the results|contributed equally to the writing of this manuscript	developed this novel mathematical approach	-	Formal analysis	YES
5123246	28185554	AM	2	formulated the problem|developed this novel mathematical approach|designed this computational tool and the mysql relational database|implemented this computational tool in matlab|selected and extracted the data sets from the public databases, pre-process and loaded them into our mysql database|loaded the datasets into matlab|conducted the interpretation of the results|contributed equally to the writing of this manuscript	designed this computational tool and the mysql relational database	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Formal analysis|Software	YES
5123246	28185554	AM	2	formulated the problem|developed this novel mathematical approach|designed this computational tool and the mysql relational database|implemented this computational tool in matlab|selected and extracted the data sets from the public databases, pre-process and loaded them into our mysql database|loaded the datasets into matlab|conducted the interpretation of the results|contributed equally to the writing of this manuscript	implemented this computational tool in matlab	Performed the experiments|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Software	YES
5123246	28185554	AM	2	formulated the problem|developed this novel mathematical approach|designed this computational tool and the mysql relational database|implemented this computational tool in matlab|selected and extracted the data sets from the public databases, pre-process and loaded them into our mysql database|loaded the datasets into matlab|conducted the interpretation of the results|contributed equally to the writing of this manuscript	selected and extracted the data sets from the public databases, pre-process and loaded them into our mysql database	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Investigation|Software	YES
5123246	28185554	AM	2	formulated the problem|developed this novel mathematical approach|designed this computational tool and the mysql relational database|implemented this computational tool in matlab|selected and extracted the data sets from the public databases, pre-process and loaded them into our mysql database|loaded the datasets into matlab|conducted the interpretation of the results|contributed equally to the writing of this manuscript	loaded the datasets into matlab	Contributed reagents/materials/analysis tools	Software	YES
5123246	28185554	AM	2	formulated the problem|developed this novel mathematical approach|designed this computational tool and the mysql relational database|implemented this computational tool in matlab|selected and extracted the data sets from the public databases, pre-process and loaded them into our mysql database|loaded the datasets into matlab|conducted the interpretation of the results|contributed equally to the writing of this manuscript	conducted the interpretation of the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5123246	28185554	AM	2	formulated the problem|developed this novel mathematical approach|designed this computational tool and the mysql relational database|implemented this computational tool in matlab|selected and extracted the data sets from the public databases, pre-process and loaded them into our mysql database|loaded the datasets into matlab|conducted the interpretation of the results|contributed equally to the writing of this manuscript	contributed equally to the writing of this manuscript	Wrote the paper	Writing - Original Draft	YES
5123246	28185554	AZ	2	loaded the datasets into matlab|contributed equally to the writing of this manuscript	loaded the datasets into matlab	Contributed reagents/materials/analysis tools	Software	YES
5123246	28185554	AZ	2	loaded the datasets into matlab|contributed equally to the writing of this manuscript	contributed equally to the writing of this manuscript	Wrote the paper	Writing - Original Draft	YES
5123246	28185554	All authors	2	read, revised and approved the final version of the manuscript	read, revised and approved the final version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5123246	28185554	DS	2	prepared figures and supplementary information	prepared figures and supplementary information	-	Visualization	YES
5123246	28185554	DSM	2	implemented this computational tool in matlab	implemented this computational tool in matlab	Performed the experiments|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Software	YES
5123246	28185554	JY	2	formulated the problem|developed this novel mathematical approach|conducted the interpretation of the results|contributed equally to the writing of this manuscript	formulated the problem	Conceived and designed the experiments	Conceptualization	YES
5123246	28185554	JY	2	formulated the problem|developed this novel mathematical approach|conducted the interpretation of the results|contributed equally to the writing of this manuscript	developed this novel mathematical approach	-	Formal analysis	YES
5123246	28185554	JY	2	formulated the problem|developed this novel mathematical approach|conducted the interpretation of the results|contributed equally to the writing of this manuscript	conducted the interpretation of the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5123246	28185554	JY	2	formulated the problem|developed this novel mathematical approach|conducted the interpretation of the results|contributed equally to the writing of this manuscript	contributed equally to the writing of this manuscript	Wrote the paper	Writing - Original Draft	YES
5487444	28702033	AA	2	carried out the experiments and analysis/interpretation of data|wrote the manuscript with contributions and discussion from all of the co-authors	carried out the experiments and analysis/interpretation of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5487444	28702033	AA	2	carried out the experiments and analysis/interpretation of data|wrote the manuscript with contributions and discussion from all of the co-authors	wrote the manuscript with contributions and discussion from all of the co-authors	Wrote the paper	Writing - Original Draft	YES
5487444	28702033	All authors	2	have given approval to the final version of the manuscript	have given approval to the final version of the manuscript	-	-	NO
5487444	28702033	EAB	2	designed the research|carried out the experiments and analysis/interpretation of data|wrote the manuscript with contributions and discussion from all of the co-authors	designed the research	Conceived and designed the experiments	Methodology	YES
5487444	28702033	EAB	2	designed the research|carried out the experiments and analysis/interpretation of data|wrote the manuscript with contributions and discussion from all of the co-authors	carried out the experiments and analysis/interpretation of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5487444	28702033	EAB	2	designed the research|carried out the experiments and analysis/interpretation of data|wrote the manuscript with contributions and discussion from all of the co-authors	wrote the manuscript with contributions and discussion from all of the co-authors	Wrote the paper	Writing - Original Draft	YES
5487444	28702033	HM	2	carried out the experiments and analysis/interpretation of data	carried out the experiments and analysis/interpretation of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5487444	28702033	MR	2	carried out the experiments and analysis/interpretation of data|wrote the manuscript with contributions and discussion from all of the co-authors	carried out the experiments and analysis/interpretation of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5487444	28702033	MR	2	carried out the experiments and analysis/interpretation of data|wrote the manuscript with contributions and discussion from all of the co-authors	wrote the manuscript with contributions and discussion from all of the co-authors	Wrote the paper	Writing - Original Draft	YES
5487444	28702033	PV-P	2	designed the research|carried out the experiments and analysis/interpretation of data|wrote the manuscript with contributions and discussion from all of the co-authors	designed the research	Conceived and designed the experiments	Methodology	YES
5487444	28702033	PV-P	2	designed the research|carried out the experiments and analysis/interpretation of data|wrote the manuscript with contributions and discussion from all of the co-authors	carried out the experiments and analysis/interpretation of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5487444	28702033	PV-P	2	designed the research|carried out the experiments and analysis/interpretation of data|wrote the manuscript with contributions and discussion from all of the co-authors	wrote the manuscript with contributions and discussion from all of the co-authors	Wrote the paper	Writing - Original Draft	YES
5487444	28702033	SV	2	carried out the experiments and analysis/interpretation of data	carried out the experiments and analysis/interpretation of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3305370	22296672	DP	7	study design, provision of significant clinical advice and manuscript preparation	study design, provision of significant clinical advice and manuscript preparation	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3305370	22296672	ET	7	study design and coordination, patients enrolment and follow-up, statistical analysis and data interpretation, manuscript preparation	study design and coordination, patients enrolment and follow-up, statistical analysis and data interpretation, manuscript preparation	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Project administration|Writing - Original Draft	YES
3305370	22296672	HB	7	hplc technique adaptation for human samples, serum analysis, data interpretation and manuscript preparation; SD-serum analysis, data interpretation, manuscript preparation	hplc technique adaptation for human samples, serum analysis, data interpretation and manuscript preparation; SD-serum analysis, data interpretation, manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3305370	22296672	ML	7	elaboration of patients consent forms and information for participants, healthy controls enrolment, study design, hplc analysis, data collection and interpretation, figures and manuscript preparation	elaboration of patients consent forms and information for participants, healthy controls enrolment, study design, hplc analysis, data collection and interpretation, figures and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Visualization|Writing - Original Draft	YES
3305370	22296672	PVB	7	overall laboratory supervision, hplc technique development, design of the study, data interpretation and manuscript preparation	overall laboratory supervision, hplc technique development, design of the study, data interpretation and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Supervision|Writing - Original Draft	YES
5698878	29120168	All authors	2	have given approval to the final version of the manuscript	have given approval to the final version of the manuscript	-	-	NO
4401722	25886591	AWT	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401722	25886591	BS	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401722	25886591	BVLN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401722	25886591	BVLN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401722	25886591	BVLN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401722	25886591	BVLN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401722	25886591	BWF	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401722	25886591	BWF	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401722	25886591	CHMK	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401722	25886591	CHMK	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401722	25886591	FAS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4401722	25886591	FAS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401722	25886591	GAB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401722	25886591	GAB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401722	25886591	GAB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401722	25886591	GAB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401722	25886591	ME	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5368956	28357118	A. Martinez	2	managed the study and involved in revision of the manuscript	managed the study and involved in revision of the manuscript	Wrote the paper	Project administration|Writing - Review & Editing	YES
5368956	28357118	F. Kobayashi	2	designed statistics involved in revision of the manuscript	designed statistics involved in revision of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5368956	28357118	L. He	2	led bioanalysis and developed the bioanalytical method and conducted the sample assay	led bioanalysis and developed the bioanalytical method and conducted the sample assay	Performed the experiments	Investigation|Methodology	YES
5368956	28357118	N. Tajima	2	designed the study and wrote manuscript	designed the study and wrote manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5368956	28357118	P. Dewland	2	is a medical advisor and contributed in revision of the manuscript	is a medical advisor and contributed in revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
3308922	22260499	AT	2	carried out most of the laboratory experiments	carried out most of the laboratory experiments	Performed the experiments	Investigation	YES
3308922	22260499	BH	2	carried out the transmission electron microscopy experiments	carried out the transmission electron microscopy experiments	Performed the experiments	Investigation	YES
3308922	22260499	HH	2	gave important input to the manuscript|carried out the transmission electron microscopy experiments	gave important input to the manuscript	-	-	NO
3308922	22260499	HH	2	gave important input to the manuscript|carried out the transmission electron microscopy experiments	carried out the transmission electron microscopy experiments	Performed the experiments	Investigation	YES
3308922	22260499	IH	2	carried out most of the laboratory experiments	carried out most of the laboratory experiments	Performed the experiments	Investigation	YES
3308922	22260499	JSzW	2	defined the research theme|conceived and designed the study|provided most of the funding|analyzed the data and interpreted the results|wrote the first draft	defined the research theme	-	-	NO
3308922	22260499	JSzW	2	defined the research theme|conceived and designed the study|provided most of the funding|analyzed the data and interpreted the results|wrote the first draft	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3308922	22260499	JSzW	2	defined the research theme|conceived and designed the study|provided most of the funding|analyzed the data and interpreted the results|wrote the first draft	provided most of the funding	-	Funding acquisition	YES
3308922	22260499	JSzW	2	defined the research theme|conceived and designed the study|provided most of the funding|analyzed the data and interpreted the results|wrote the first draft	analyzed the data and interpreted the results	Analyzed the data	Formal analysis	YES
3308922	22260499	JSzW	2	defined the research theme|conceived and designed the study|provided most of the funding|analyzed the data and interpreted the results|wrote the first draft	wrote the first draft	Wrote the paper	Writing - Original Draft	YES
3308922	22260499	JVL	2	gave important input to the manuscript	gave important input to the manuscript	-	-	NO
3308922	22260499	JvL	2	defined the research theme|conceived and designed the study|analyzed the data and interpreted the results	defined the research theme	-	-	NO
3308922	22260499	JvL	2	defined the research theme|conceived and designed the study|analyzed the data and interpreted the results	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3308922	22260499	JvL	2	defined the research theme|conceived and designed the study|analyzed the data and interpreted the results	analyzed the data and interpreted the results	Analyzed the data	Formal analysis	YES
3308922	22260499	PH	2	conceived and designed the study|carried out most of the laboratory experiments|analyzed the data and interpreted the results|wrote the first draft	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3308922	22260499	PH	2	conceived and designed the study|carried out most of the laboratory experiments|analyzed the data and interpreted the results|wrote the first draft	carried out most of the laboratory experiments	Performed the experiments	Investigation	YES
3308922	22260499	PH	2	conceived and designed the study|carried out most of the laboratory experiments|analyzed the data and interpreted the results|wrote the first draft	analyzed the data and interpreted the results	Analyzed the data	Formal analysis	YES
3308922	22260499	PH	2	conceived and designed the study|carried out most of the laboratory experiments|analyzed the data and interpreted the results|wrote the first draft	wrote the first draft	Wrote the paper	Writing - Original Draft	YES
3308922	22260499	SF	2	conceived and designed the study|carried out most of the laboratory experiments|analyzed the data and interpreted the results	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3308922	22260499	SF	2	conceived and designed the study|carried out most of the laboratory experiments|analyzed the data and interpreted the results	carried out most of the laboratory experiments	Performed the experiments	Investigation	YES
3308922	22260499	SF	2	conceived and designed the study|carried out most of the laboratory experiments|analyzed the data and interpreted the results	analyzed the data and interpreted the results	Analyzed the data	Formal analysis	YES
3308922	22260499	VM	2	carried out most of the laboratory experiments	carried out most of the laboratory experiments	Performed the experiments	Investigation	YES
3308922	22260499	WS	2	gave important input to the manuscript	gave important input to the manuscript	-	-	NO
5123250	28185558	DS	2	who also wrote the paper	who also wrote the paper	Wrote the paper	Writing - Original Draft	YES
5123250	28185558	DSM	2	helped to collect and handle the data, and to design and set up the website	helped to collect and handle the data, and to design and set up the website	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Software	YES
5123250	28185558	GCV	2	who also wrote the paper	who also wrote the paper	Wrote the paper	Writing - Original Draft	YES
5487450	28702040	CL	2	provided sapk10 and osabil2 transgenic plants	provided sapk10 and osabil2 transgenic plants	Performed the experiments	Investigation	YES
5487450	28702040	CM	2	provided ospin-gus transgenic plants	provided ospin-gus transgenic plants	Performed the experiments	Investigation	YES
5487450	28702040	HW	2	helped to prepare material for rna seq	helped to prepare material for rna seq	Performed the experiments	Investigation	YES
5487450	28702040	SS	2	put forward improvement advise	put forward improvement advise	-	-	NO
5487450	28702040	TW	2	conceived the research and planned the experiments|performed all of the experiments|wrote the manuscript	conceived the research and planned the experiments	Conceived and designed the experiments	Conceptualization	YES
5487450	28702040	TW	2	conceived the research and planned the experiments|performed all of the experiments|wrote the manuscript	performed all of the experiments	Performed the experiments	Investigation	YES
5487450	28702040	TW	2	conceived the research and planned the experiments|performed all of the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5487450	28702040	XW	2	conceived the research and planned the experiments|wrote the manuscript	conceived the research and planned the experiments	Conceived and designed the experiments	Conceptualization	YES
5487450	28702040	XW	2	conceived the research and planned the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5487450	28702040	YJ	2	helped to prepare material for rna seq	helped to prepare material for rna seq	Performed the experiments	Investigation	YES
5487450	28702040	ZW	2	performed the rna seq data analysis	performed the rna seq data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4401723	25886624	CEP	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401723	25886624	CEP	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401723	25886624	DEF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401723	25886624	DEF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401723	25886624	DEF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401723	25886624	DEF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401723	25886624	DEF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401723	25886624	EH	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401723	25886624	EH	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4401723	25886624	EH	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401723	25886624	JC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401723	25886624	JC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4401723	25886624	JC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401723	25886624	JV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401723	25886624	JV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401723	25886624	JV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401723	25886624	JV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401723	25886624	JV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401723	25886624	LP	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401723	25886624	LP	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4401723	25886624	LP	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401723	25886624	RJV	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401723	25886624	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401723	25886624	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4401723	25886624	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401723	25886624	VL	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401723	25886624	VL	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4457413	26137520	All authors	PLoS52	discussed the results and edited the manuscript	discussed the results and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
4457413	26137520	CCH	PLoS52	recruited hiv-1 patients	recruited hiv-1 patients	Performed the experiments	Investigation	YES
4457413	26137520	HMS	PLoS52	executed the yeast two-hybrid experiment	executed the yeast two-hybrid experiment	Performed the experiments	Investigation	YES
4457413	26137520	LMH	PLoS52	designed the study|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
4457413	26137520	LMH	PLoS52	designed the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4457413	26137520	PLS	PLoS52	performed the experiments|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
4457413	26137520	PLS	PLoS52	performed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4457413	26137520	SCC	PLoS52	recruited hiv-1 patients	recruited hiv-1 patients	Performed the experiments	Investigation	YES
4457413	26137520	SWH	PLoS52	recruited hiv-1 patients	recruited hiv-1 patients	Performed the experiments	Investigation	YES
4457413	26137520	WHS	PLoS52	performed the experiments|recruited hiv-1 patients|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
4457413	26137520	WHS	PLoS52	performed the experiments|recruited hiv-1 patients|wrote the manuscript	recruited hiv-1 patients	Performed the experiments	Investigation	YES
4457413	26137520	WHS	PLoS52	performed the experiments|recruited hiv-1 patients|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4457413	26137520	YHC	PLoS52	performed the experiments|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
4457413	26137520	YHC	PLoS52	performed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4457413	26137520	YMC	PLoS52	recruited hiv-1 patients	recruited hiv-1 patients	Performed the experiments	Investigation	YES
4457413	26137520	YPC	PLoS52	performed the experiments|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
4457413	26137520	YPC	PLoS52	performed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3308925	22333070	HIV	2	screening and confirmation, preparation of the manuscript	screening and confirmation, preparation of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5487464	28702048	HW	PLoS52	initiated and designed the project	initiated and designed the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5487464	28702048	JM	PLoS52	made the mitotic chromosome preparations followed by fish analysis	made the mitotic chromosome preparations followed by fish analysis	-	-	NO
5487464	28702048	MK	PLoS52	initiated and designed the project	initiated and designed the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5487464	28702048	MM	PLoS52	initiated and designed the study|made the mitotic chromosome preparations followed by fish analysis|performed the molecular marker analysis and analyzed the data|wrote the paper	initiated and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5487464	28702048	MM	PLoS52	initiated and designed the study|made the mitotic chromosome preparations followed by fish analysis|performed the molecular marker analysis and analyzed the data|wrote the paper	made the mitotic chromosome preparations followed by fish analysis	-	-	NO
5487464	28702048	MM	PLoS52	initiated and designed the study|made the mitotic chromosome preparations followed by fish analysis|performed the molecular marker analysis and analyzed the data|wrote the paper	performed the molecular marker analysis and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5487464	28702048	MM	PLoS52	initiated and designed the study|made the mitotic chromosome preparations followed by fish analysis|performed the molecular marker analysis and analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3317876	22409789	SM	2	participated in the design of the study and draft the manuscript	participated in the design of the study and draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3317876	22409789	SN	2	participated in the design of the study and draft the manuscript	participated in the design of the study and draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3317876	22409789	SS	2	participated in the design of the study and draft the manuscript	participated in the design of the study and draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3317876	22409789	ST	2	participated in the design of the study and draft the manuscript	participated in the design of the study and draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3317876	22409789	WM	2	participated in the design of the study, statistical analysis and draft the manuscript	participated in the design of the study, statistical analysis and draft the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5123294	28185551	AB	2	conceived the study, modeled the validation process, and analyzed the experiments|modeled the predictor|modeled the controller|wrote the manuscript	conceived the study, modeled the validation process, and analyzed the experiments	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology|Validation	YES
5123294	28185551	AB	2	conceived the study, modeled the validation process, and analyzed the experiments|modeled the predictor|modeled the controller|wrote the manuscript	modeled the predictor	Performed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5123294	28185551	AB	2	conceived the study, modeled the validation process, and analyzed the experiments|modeled the predictor|modeled the controller|wrote the manuscript	modeled the controller	Performed the experiments	Methodology	YES
5123294	28185551	AB	2	conceived the study, modeled the validation process, and analyzed the experiments|modeled the predictor|modeled the controller|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5123294	28185551	AP	2	wrote the draft code for constructing the gene models	wrote the draft code for constructing the gene models	Performed the experiments|Wrote the paper	Investigation|Methodology|Software|Writing - Original Draft	YES
5123294	28185551	JSV	2	conceived the study, modeled the validation process, and analyzed the experiments|modeled the predictor|wrote the final code for constructing the gene models|wrote the code for the predictor|revised the manuscript	conceived the study, modeled the validation process, and analyzed the experiments	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology|Validation	YES
5123294	28185551	JSV	2	conceived the study, modeled the validation process, and analyzed the experiments|modeled the predictor|wrote the final code for constructing the gene models|wrote the code for the predictor|revised the manuscript	modeled the predictor	Performed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5123294	28185551	JSV	2	conceived the study, modeled the validation process, and analyzed the experiments|modeled the predictor|wrote the final code for constructing the gene models|wrote the code for the predictor|revised the manuscript	wrote the final code for constructing the gene models	Performed the experiments|Wrote the paper	Investigation|Methodology|Software|Writing - Original Draft	YES
5123294	28185551	JSV	2	conceived the study, modeled the validation process, and analyzed the experiments|modeled the predictor|wrote the final code for constructing the gene models|wrote the code for the predictor|revised the manuscript	wrote the code for the predictor	Analyzed the data|Wrote the paper	Formal analysis|Software|Writing - Original Draft	YES
5123294	28185551	JSV	2	conceived the study, modeled the validation process, and analyzed the experiments|modeled the predictor|wrote the final code for constructing the gene models|wrote the code for the predictor|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5123294	28185551	KS	2	conceived the study, modeled the validation process, and analyzed the experiments|modeled the predictor|modeled the controller|wrote the code for the controller|revised the manuscript	conceived the study, modeled the validation process, and analyzed the experiments	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology|Validation	YES
5123294	28185551	KS	2	conceived the study, modeled the validation process, and analyzed the experiments|modeled the predictor|modeled the controller|wrote the code for the controller|revised the manuscript	modeled the predictor	Performed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5123294	28185551	KS	2	conceived the study, modeled the validation process, and analyzed the experiments|modeled the predictor|modeled the controller|wrote the code for the controller|revised the manuscript	modeled the controller	Performed the experiments	Methodology	YES
5123294	28185551	KS	2	conceived the study, modeled the validation process, and analyzed the experiments|modeled the predictor|modeled the controller|wrote the code for the controller|revised the manuscript	wrote the code for the controller	Wrote the paper	Software|Writing - Original Draft	YES
5123294	28185551	KS	2	conceived the study, modeled the validation process, and analyzed the experiments|modeled the predictor|modeled the controller|wrote the code for the controller|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5123294	28185551	PG	2	wrote the draft code for constructing the gene models	wrote the draft code for constructing the gene models	Performed the experiments|Wrote the paper	Investigation|Methodology|Software|Writing - Original Draft	YES
5123294	28185551	SB	2	conceived the study, modeled the validation process, and analyzed the experiments|modeled the predictor|wrote the final code for constructing the gene models|wrote the code for the predictor|revised the manuscript	conceived the study, modeled the validation process, and analyzed the experiments	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology|Validation	YES
5123294	28185551	SB	2	conceived the study, modeled the validation process, and analyzed the experiments|modeled the predictor|wrote the final code for constructing the gene models|wrote the code for the predictor|revised the manuscript	modeled the predictor	Performed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5123294	28185551	SB	2	conceived the study, modeled the validation process, and analyzed the experiments|modeled the predictor|wrote the final code for constructing the gene models|wrote the code for the predictor|revised the manuscript	wrote the final code for constructing the gene models	Performed the experiments|Wrote the paper	Investigation|Methodology|Software|Writing - Original Draft	YES
5123294	28185551	SB	2	conceived the study, modeled the validation process, and analyzed the experiments|modeled the predictor|wrote the final code for constructing the gene models|wrote the code for the predictor|revised the manuscript	wrote the code for the predictor	Analyzed the data|Wrote the paper	Formal analysis|Software|Writing - Original Draft	YES
5123294	28185551	SB	2	conceived the study, modeled the validation process, and analyzed the experiments|modeled the predictor|wrote the final code for constructing the gene models|wrote the code for the predictor|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4401724	25885665	CAC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4401724	25885665	CAC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401724	25885665	FR	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401724	25885665	JIRR	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401724	25885665	JIRR	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401724	25885665	JIRR	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401724	25885665	LGO	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401724	25885665	LGO	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401724	25885665	LGO	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401724	25885665	LGS	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401724	25885665	LGS	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401724	25885665	MAGM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401724	25885665	MAGM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401724	25885665	MAGM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401724	25885665	MCPA	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401724	25885665	RM	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401724	25885665	RM	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401724	25885665	RR	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401724	25885665	RR	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5368959	28357121	Adriana Mercado	1	Contributed new reagents or analytic tools	Contributed new reagents or analytic tools	Contributed reagents/materials/analysis tools	Resources	YES
5368959	28357121	Asim K. Mandal	1	Participated in research design|Conducted experiments|Performed data analysis|Wrote or contributed to the writing of the manuscript	Participated in research design	Conceived and designed the experiments	-	YES
5368959	28357121	Asim K. Mandal	1	Participated in research design|Conducted experiments|Performed data analysis|Wrote or contributed to the writing of the manuscript	Conducted experiments	Performed the experiments	Investigation	YES
5368959	28357121	Asim K. Mandal	1	Participated in research design|Conducted experiments|Performed data analysis|Wrote or contributed to the writing of the manuscript	Performed data analysis	Analyzed the data	Formal analysis	YES
5368959	28357121	Asim K. Mandal	1	Participated in research design|Conducted experiments|Performed data analysis|Wrote or contributed to the writing of the manuscript	Wrote or contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5368959	28357121	David B. Mount	1	Participated in research design|Performed data analysis|Wrote or contributed to the writing of the manuscript	Participated in research design	Conceived and designed the experiments	-	YES
5368959	28357121	David B. Mount	1	Participated in research design|Performed data analysis|Wrote or contributed to the writing of the manuscript	Performed data analysis	Analyzed the data	Formal analysis	YES
5368959	28357121	David B. Mount	1	Participated in research design|Performed data analysis|Wrote or contributed to the writing of the manuscript	Wrote or contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5368959	28357121	Kambiz Zandi-Nejad	1	Contributed new reagents or analytic tools	Contributed new reagents or analytic tools	Contributed reagents/materials/analysis tools	Resources	YES
3320559	22339893	AE	2	provided statistical support and assistance with various aspects of the analysis	provided statistical support and assistance with various aspects of the analysis	Analyzed the data	Formal analysis	YES
3320559	22339893	AG	2	had multiple responsibilities related to this cohort, including data collection and oversight at study sites at which participants were followed	had multiple responsibilities related to this cohort, including data collection and oversight at study sites at which participants were followed	Performed the experiments	Investigation|Supervision	YES
3320559	22339893	AL	2	was lead author on planning and coordinating the analysis, and drafting interim and final versions of the manuscript	was lead author on planning and coordinating the analysis, and drafting interim and final versions of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft	YES
3320559	22339893	BA	2	had multiple responsibilities related to this cohort, including data collection and oversight at study sites at which participants were followed	had multiple responsibilities related to this cohort, including data collection and oversight at study sites at which participants were followed	Performed the experiments	Investigation|Supervision	YES
3320559	22339893	EK	2	provided statistical support and assistance with various aspects of the analysis	provided statistical support and assistance with various aspects of the analysis	Analyzed the data	Formal analysis	YES
3320559	22339893	GM	2	had multiple responsibilities related to this cohort, including data collection and oversight at study sites at which participants were followed	had multiple responsibilities related to this cohort, including data collection and oversight at study sites at which participants were followed	Performed the experiments	Investigation|Supervision	YES
3320559	22339893	JO	2	had multiple responsibilities related to this cohort, including data collection and oversight at study sites at which participants were followed	had multiple responsibilities related to this cohort, including data collection and oversight at study sites at which participants were followed	Performed the experiments	Investigation|Supervision	YES
3320559	22339893	LE	2	provided statistical support and assistance with various aspects of the analysis	provided statistical support and assistance with various aspects of the analysis	Analyzed the data	Formal analysis	YES
3320559	22339893	NC	2	had multiple responsibilities related to this cohort, including data collection and oversight at study sites at which participants were followed	had multiple responsibilities related to this cohort, including data collection and oversight at study sites at which participants were followed	Performed the experiments	Investigation|Supervision	YES
3320559	22339893	PG	2	provided statistical support and assistance with various aspects of the analysis	provided statistical support and assistance with various aspects of the analysis	Analyzed the data	Formal analysis	YES
5487473	28702043	JR	PLoS52	provided the idea of the work and designed the experiments|conducted the experiments|participated in the interpretation of results and critically reviewed the manuscript|wrote the paper	provided the idea of the work and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5487473	28702043	JR	PLoS52	provided the idea of the work and designed the experiments|conducted the experiments|participated in the interpretation of results and critically reviewed the manuscript|wrote the paper	conducted the experiments	Performed the experiments	Investigation	YES
5487473	28702043	JR	PLoS52	provided the idea of the work and designed the experiments|conducted the experiments|participated in the interpretation of results and critically reviewed the manuscript|wrote the paper	participated in the interpretation of results and critically reviewed the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5487473	28702043	JR	PLoS52	provided the idea of the work and designed the experiments|conducted the experiments|participated in the interpretation of results and critically reviewed the manuscript|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5487473	28702043	RF	PLoS52	participated in the interpretation of results and critically reviewed the manuscript	participated in the interpretation of results and critically reviewed the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5487473	28702043	UC	PLoS52	provided the idea of the work and designed the experiments|participated in the interpretation of results and critically reviewed the manuscript	provided the idea of the work and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5487473	28702043	UC	PLoS52	provided the idea of the work and designed the experiments|participated in the interpretation of results and critically reviewed the manuscript	participated in the interpretation of results and critically reviewed the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5123299	28185563	All authors	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5123299	28185563	CJ	2	conceived of the study and designed it	conceived of the study and designed it	Conceived and designed the experiments	Conceptualization|Methodology	YES
5123299	28185563	LN	2	conceived of the study and designed it	conceived of the study and designed it	Conceived and designed the experiments	Conceptualization|Methodology	YES
5123299	28185563	YY	2	conceived of the study and designed it|implemented the method and conducted all the data analyses	conceived of the study and designed it	Conceived and designed the experiments	Conceptualization|Methodology	YES
5123299	28185563	YY	2	conceived of the study and designed it|implemented the method and conducted all the data analyses	implemented the method and conducted all the data analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4401725	25886502	CJ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401725	25886502	CJ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401725	25886502	CJ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401725	25886502	CJ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401725	25886502	CM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401725	25886502	CM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401725	25886502	CM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401725	25886502	CM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401725	25886502	DJN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401725	25886502	DJN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401725	25886502	DJN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401725	25886502	DJN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401725	25886502	JKG	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401725	25886502	JKG	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401725	25886502	JKG	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401725	25886502	PP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401725	25886502	TLY	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4450238	26090399	Da Silva	2	share equal contribution in authorship	share equal contribution in authorship	-	-	NO
4450238	26090399	Patricia Maria Lourenco	2	share equal contribution in authorship	share equal contribution in authorship	-	-	NO
4450238	26090399	Silvia Amaral Goncalves	2	share equal contribution in authorship	share equal contribution in authorship	-	-	NO
3324378	22405335	AA	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
3324378	22405335	All authors	2	participated in the design of the study	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
3324378	22405335	DAC	2	reviewed the paper	reviewed the paper	Wrote the paper	Writing - Review & Editing	YES
3324378	22405335	GJD	2	reviewed the paper	reviewed the paper	Wrote the paper	Writing - Review & Editing	YES
3324378	22405335	GVM	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
3324378	22405335	JS	2	performed the laboratory tests	performed the laboratory tests	Performed the experiments	Investigation	YES
3324378	22405335	KR	2	reviewed the paper	reviewed the paper	Wrote the paper	Writing - Review & Editing	YES
3324378	22405335	PM	2	reviewed the paper	reviewed the paper	Wrote the paper	Writing - Review & Editing	YES
3324378	22405335	SC	2	performed the laboratory tests	performed the laboratory tests	Performed the experiments	Investigation	YES
3324378	22405335	SL	2	performed the laboratory tests	performed the laboratory tests	Performed the experiments	Investigation	YES
3324378	22405335	SRL	2	reviewed the paper	reviewed the paper	Wrote the paper	Writing - Review & Editing	YES
2790148	19997538	Karageorgos Athanasios	2	participated in patient care and collected data	participated in patient care and collected data	Performed the experiments	Investigation	YES
2790148	19997538	Karanikolas Menelaos	2	wrote, edited and submitted the manuscript	wrote, edited and submitted the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
2790148	19997538	Marangos Markos	2	participated in patient care and directed antibiotic therapy	participated in patient care and directed antibiotic therapy	Performed the experiments	Investigation|Supervision	YES
2790148	19997538	Matzaroglou Charis	2	evaluated, treated and did follow-up on all patients	evaluated, treated and did follow-up on all patients	Performed the experiments	Investigation	YES
2790148	19997538	Panagiotopoulos Elias	2	supervised patient care and edited manuscript	supervised patient care and edited manuscript	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Review & Editing	YES
2790148	19997538	Velissaris Dimitrios	2	collected data and edited the manuscript	collected data and edited the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5487484	28702042	BZ	PLoS52	conceived and designed the experiments|analyzed the data|edited the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5487484	28702042	BZ	PLoS52	conceived and designed the experiments|analyzed the data|edited the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5487484	28702042	BZ	PLoS52	conceived and designed the experiments|analyzed the data|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5487484	28702042	DW	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5487484	28702042	FL	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5487484	28702042	ML	PLoS52	conceived and designed the experiments|edited the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5487484	28702042	ML	PLoS52	conceived and designed the experiments|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5487484	28702042	PC	PLoS52	conceived and designed the experiments|analyzed the data|edited the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5487484	28702042	PC	PLoS52	conceived and designed the experiments|analyzed the data|edited the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5487484	28702042	PC	PLoS52	conceived and designed the experiments|analyzed the data|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5487484	28702042	YB	PLoS52	conceived and designed the experiments|conducted bioinformatics analysis|performed the experiments|analyzed the data|drafted the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5487484	28702042	YB	PLoS52	conceived and designed the experiments|conducted bioinformatics analysis|performed the experiments|analyzed the data|drafted the manuscript	conducted bioinformatics analysis	Performed the experiments	Formal analysis|Investigation	YES
5487484	28702042	YB	PLoS52	conceived and designed the experiments|conducted bioinformatics analysis|performed the experiments|analyzed the data|drafted the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5487484	28702042	YB	PLoS52	conceived and designed the experiments|conducted bioinformatics analysis|performed the experiments|analyzed the data|drafted the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5487484	28702042	YB	PLoS52	conceived and designed the experiments|conducted bioinformatics analysis|performed the experiments|analyzed the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5487484	28702042	YL	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5123300	28185555	MN	2	implemented the methods, performed the analyses, and wrote the first draft of the paper	implemented the methods, performed the analyses, and wrote the first draft of the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5123300	28185555	TW	2	wrote the final draft of the paper	wrote the final draft of the paper	Wrote the paper	Writing - Original Draft	YES
5368961	28357123	AI	1	Data abstraction|Writing the manuscript	Data abstraction	-	-	NO
5368961	28357123	AI	1	Data abstraction|Writing the manuscript	Writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5368961	28357123	AOA	1	Conception and design of the study|Writing the manuscript	Conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5368961	28357123	AOA	1	Conception and design of the study|Writing the manuscript	Writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5368961	28357123	CS	1	Data abstraction|Writing the manuscript	Data abstraction	-	-	NO
5368961	28357123	CS	1	Data abstraction|Writing the manuscript	Writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5368961	28357123	IAO	1	Conception and design of the study|Data analysis|Writing the manuscript	Conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5368961	28357123	IAO	1	Conception and design of the study|Data analysis|Writing the manuscript	Data analysis	Analyzed the data	Formal analysis	YES
5368961	28357123	IAO	1	Conception and design of the study|Data analysis|Writing the manuscript	Writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5368961	28357123	KAO	1	Conception and design of the study|Data abstraction|Data analysis|Writing the manuscript	Conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5368961	28357123	KAO	1	Conception and design of the study|Data abstraction|Data analysis|Writing the manuscript	Data abstraction	-	-	NO
5368961	28357123	KAO	1	Conception and design of the study|Data abstraction|Data analysis|Writing the manuscript	Data analysis	Analyzed the data	Formal analysis	YES
5368961	28357123	KAO	1	Conception and design of the study|Data abstraction|Data analysis|Writing the manuscript	Writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5368961	28357123	OA	1	Writing the manuscript	Writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5368961	28357123	YO	1	Data abstraction|Writing the manuscript	Data abstraction	-	-	NO
5368961	28357123	YO	1	Data abstraction|Writing the manuscript	Writing the manuscript	Wrote the paper	Writing - Original Draft	YES
4401726	25884834	AA	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401726	25884834	AA	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401726	25884834	CD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401726	25884834	CD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401726	25884834	CD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401726	25884834	CD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401726	25884834	DPM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401726	25884834	DPM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401726	25884834	DPM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401726	25884834	EN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401726	25884834	EN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401726	25884834	EN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401726	25884834	EN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401726	25884834	GDS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401726	25884834	GDS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401726	25884834	JPC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401726	25884834	JPC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401726	25884834	JPC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401726	25884834	MC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401726	25884834	MC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401726	25884834	MC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401726	25884834	SE	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401726	25884834	SE	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401726	25884834	SE	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3338393	22409770	All the authors	2	contributed equally to the manuscre therapeutic session	contributed equally to the manuscre therapeutic session	-	-	NO
4457436	26137519	BG	2	performed and analyzed the experiments|performed the electron microscopy	performed and analyzed the experiments	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4457436	26137519	BG	2	performed and analyzed the experiments|performed the electron microscopy	performed the electron microscopy	Performed the experiments	Investigation	YES
4457436	26137519	CM	2	coordinated the project and planned the experiments|wrote the manuscript with input from the other authors	coordinated the project and planned the experiments	Conceived and designed the experiments	Conceptualization|Project administration	YES
4457436	26137519	CM	2	coordinated the project and planned the experiments|wrote the manuscript with input from the other authors	wrote the manuscript with input from the other authors	Wrote the paper	Writing - Original Draft	YES
4457436	26137519	HN	2	performed and analyzed the experiments|wrote the manuscript with input from the other authors	performed and analyzed the experiments	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4457436	26137519	HN	2	performed and analyzed the experiments|wrote the manuscript with input from the other authors	wrote the manuscript with input from the other authors	Wrote the paper	Writing - Original Draft	YES
4457436	26137519	JD	2	contributed to the interpretation of the obtained experimental data	contributed to the interpretation of the obtained experimental data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
4457436	26137519	KT	2	contributed to the interpretation of the obtained experimental data	contributed to the interpretation of the obtained experimental data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
4457436	26137519	SR	2	coordinated the project and planned the experiments	coordinated the project and planned the experiments	Conceived and designed the experiments	Conceptualization|Project administration	YES
4457436	26137519	UZ	2	coordinated the project and planned the experiments	coordinated the project and planned the experiments	Conceived and designed the experiments	Conceptualization|Project administration	YES
5487486	28702045	FS	2	designed the experiments and wrote the paper|performed all experiments and analyzed the data	designed the experiments and wrote the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5487486	28702045	FS	2	designed the experiments and wrote the paper|performed all experiments and analyzed the data	performed all experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5487486	28702045	GH	2	designed the experiments and wrote the paper	designed the experiments and wrote the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5487486	28702045	GY	2	designed the experiments and wrote the paper	designed the experiments and wrote the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5487486	28702045	JL	2	helped to conduct the experiments	helped to conduct the experiments	Performed the experiments	Investigation	YES
5487486	28702045	LJ	2	helped to construct the relevant vectors	helped to construct the relevant vectors	Performed the experiments	Investigation	YES
5487486	28702045	QW	2	helped to conduct the experiments	helped to conduct the experiments	Performed the experiments	Investigation	YES
5487486	28702045	TY	2	helped to construct the relevant vectors	helped to construct the relevant vectors	Performed the experiments	Investigation	YES
5487486	28702045	XL	2	performed all experiments and analyzed the data	performed all experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5487486	28702045	YW	2	participated in partial experiments	participated in partial experiments	Performed the experiments	Investigation	YES
4450242	26090390	Marianne Kramer	2	equally participated in the work	equally participated in the work	-	-	NO
4450242	26090390	Sandra Pierredon	2	equally participated in the work	equally participated in the work	-	-	NO
5368962	28357124	All authors	2	approved the final manuscript	approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5368962	28357124	SMB	2	participated in its design, implementation, statistical analysis, and drawing of inferences|took part in the manuscript writing process	participated in its design, implementation, statistical analysis, and drawing of inferences	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5368962	28357124	SMB	2	participated in its design, implementation, statistical analysis, and drawing of inferences|took part in the manuscript writing process	took part in the manuscript writing process	Wrote the paper	Writing - Original Draft	YES
3342087	22429560	AS	2	was the pi on the study	was the pi on the study	-	-	NO
3342087	22429560	JO	2	conducted field research and assisted with contextual data and result interpretation	conducted field research and assisted with contextual data and result interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3342087	22429560	MC	2	contributed substantially in reviewing the manuscript and guided data analysis	contributed substantially in reviewing the manuscript and guided data analysis	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Supervision|Writing - Review & Editing	YES
3342087	22429560	MP	2	conducted the statistical data analysis	conducted the statistical data analysis	Analyzed the data	Formal analysis	YES
3342087	22429560	MT	2	provided overall guidance for the research and manuscript preparation	provided overall guidance for the research and manuscript preparation	Wrote the paper	Supervision|Writing - Original Draft	YES
3342087	22429560	NK	2	conducted field research and assisted with contextual data and result interpretation	conducted field research and assisted with contextual data and result interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3342087	22429560	SG	2	set up the data collection using hand held computers and helped with data interpretation	set up the data collection using hand held computers and helped with data interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
3342087	22429560	SL	2	participated in the design of the study and contributed to the manuscript	participated in the design of the study and contributed to the manuscript	Conceived and designed the experiments	Methodology	YES
4401727	25886355	AM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401727	25886355	AM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401727	25886355	AM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401727	25886355	DTB	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401727	25886355	DTB	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401727	25886355	JV	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401727	25886355	JV	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401727	25886355	JV	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401727	25886355	PA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401727	25886355	PA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401727	25886355	PA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401727	25886355	SP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401727	25886355	SP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401727	25886355	SP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401727	25886355	SP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401727	25886355	SP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3417186	22919335	Chia-Cheng Tseng	2	contributed equally to the article	contributed equally to the article	-	-	NO
3417186	22919335	Kuo-Tung Huang	2	contributed equally to the article	contributed equally to the article	-	-	NO
3417186	22919335	Meng-Chih Lin	2	contributed equally to the article	contributed equally to the article	-	-	NO
3417186	22919335	Wen-Feng Fang	2	contributed equally to the article	contributed equally to the article	-	-	NO
5123309	28185574	ES	2	both designed the algorithm, proved theoretical results, analyzed the data, and wrote the manuscript|implemented the code and performed simulation studies	both designed the algorithm, proved theoretical results, analyzed the data, and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Software|Writing - Original Draft	YES
5123309	28185574	ES	2	both designed the algorithm, proved theoretical results, analyzed the data, and wrote the manuscript|implemented the code and performed simulation studies	implemented the code and performed simulation studies	Performed the experiments	Formal analysis|Investigation	YES
5123309	28185574	SM	2	both designed the algorithm, proved theoretical results, analyzed the data, and wrote the manuscript	both designed the algorithm, proved theoretical results, analyzed the data, and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Software|Writing - Original Draft	YES
5487487	28702041	HN	2	performed the research	performed the research	Performed the experiments	Investigation	YES
5487487	28702041	HW	2	designed the experiments|performed the research|drafted the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5487487	28702041	HW	2	designed the experiments|performed the research|drafted the manuscript	performed the research	Performed the experiments	Investigation	YES
5487487	28702041	HW	2	designed the experiments|performed the research|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5487487	28702041	LM	2	revised the paper and contributed reagents/materials/analysis tools	revised the paper and contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Review & Editing	YES
5487487	28702041	ML	2	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5487487	28702041	YZ	2	performed the research	performed the research	Performed the experiments	Investigation	YES
4471147	26097890	F.L.C.	2	prepared figures and tables	prepared figures and tables	-	Visualization	YES
4471147	26097890	H.K.	2	performed nmr and analysed the data	performed nmr and analysed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4471147	26097890	L.C.	2	prepared figures and tables	prepared figures and tables	-	Visualization	YES
4471147	26097890	M.K.	2	planned the project|prepared figures and tables|wrote the manuscript and all authors read, corrected, and approved the final manuscript	planned the project	Conceived and designed the experiments	Conceptualization	YES
4471147	26097890	M.K.	2	planned the project|prepared figures and tables|wrote the manuscript and all authors read, corrected, and approved the final manuscript	prepared figures and tables	-	Visualization	YES
4471147	26097890	M.K.	2	planned the project|prepared figures and tables|wrote the manuscript and all authors read, corrected, and approved the final manuscript	wrote the manuscript and all authors read, corrected, and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4471147	26097890	N.T.	2	prepared figures and tables	prepared figures and tables	-	Visualization	YES
4471147	26097890	P.A.	2	performed molecular docking	performed molecular docking	Performed the experiments	Investigation	YES
4471147	26097890	P.V.C.	2	planned the project	planned the project	Conceived and designed the experiments	Conceptualization	YES
4471147	26097890	S.V.W.	2	performed generation and analysis of stable cell lines	performed generation and analysis of stable cell lines	Performed the experiments	Investigation	YES
4471147	26097890	S.W.	2	performed computational calculations using multiple thermodynamic integration simulations|prepared figures and tables	performed computational calculations using multiple thermodynamic integration simulations	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4471147	26097890	S.W.	2	performed computational calculations using multiple thermodynamic integration simulations|prepared figures and tables	prepared figures and tables	-	Visualization	YES
4471147	26097890	T.D.B.	2	planned the project|prepared figures and tables	planned the project	Conceived and designed the experiments	Conceptualization	YES
4471147	26097890	T.D.B.	2	planned the project|prepared figures and tables	prepared figures and tables	-	Visualization	YES
3976449	24711751	CAAG	2	obtained the clinical data	obtained the clinical data	Performed the experiments	Investigation	YES
3976449	24711751	CAE	2	conceived and designed the study protocol, performed the data analysis, and wrote the manuscript	conceived and designed the study protocol, performed the data analysis, and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
3976449	24711751	ERS	2	performed the data analysis	performed the data analysis	Analyzed the data	Formal analysis	YES
3976449	24711751	JHT	2	performed the data analysis	performed the data analysis	Analyzed the data	Formal analysis	YES
3976449	24711751	LFME	2	obtained the clinical data	obtained the clinical data	Performed the experiments	Investigation	YES
3976449	24711751	LFSA	2	performed the data analysis	performed the data analysis	Analyzed the data	Formal analysis	YES
3348055	22490062	AA	2	wrote the first draft of the paper and all authors contributed comments and suggestions to various draft versions	wrote the first draft of the paper and all authors contributed comments and suggestions to various draft versions	Wrote the paper	Writing - Original Draft	YES
3348055	22490062	TB	2	participated in study design and data collection	participated in study design and data collection	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3348055	22490062	YM	2	participated in study design and coordinated the study	participated in study design and coordinated the study	Conceived and designed the experiments	Methodology|Project administration	YES
4401728	25885790	BK	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401728	25885790	BK	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401728	25885790	BO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401728	25885790	BO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401728	25885790	BO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401728	25885790	BO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401728	25885790	GJ	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401728	25885790	GJ	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3349607	22524486	All authors	2	contributed equally to the manuscript	contributed equally to the manuscript	-	-	NO
5368966	28357128	AO	2	were responsible for this study and designed the proposal and oversaw the work	were responsible for this study and designed the proposal and oversaw the work	Conceived and designed the experiments	Methodology|Supervision	YES
5368966	28357128	BNwankwo	2	performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
5368966	28357128	Casandra Elegbaje	2	were the research associates implementing the study, managing the data collections during the initial program	were the research associates implementing the study, managing the data collections during the initial program	Performed the experiments	Investigation	YES
5368966	28357128	Godwin N. Ntadom	2	were the research associates implementing the study, managing the data collections during the initial program	were the research associates implementing the study, managing the data collections during the initial program	Performed the experiments	Investigation	YES
5368966	28357128	O Isah	2	revised it critically for important intellectual content and all authors read and approved the final manuscript	revised it critically for important intellectual content and all authors read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5368966	28357128	Suku Comfort	2	were responsible for this study and designed the proposal and oversaw the work	were responsible for this study and designed the proposal and oversaw the work	Conceived and designed the experiments	Methodology|Supervision	YES
5368966	28357128	Sulayman T. Balogun	2	were the research associates implementing the study, managing the data collections during the initial program	were the research associates implementing the study, managing the data collections during the initial program	Performed the experiments	Investigation	YES
5368966	28357128	UP	2	was responsible for database extraction, data entry, and pre-analysis management	was responsible for database extraction, data entry, and pre-analysis management	Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Formal analysis|Software	YES
3352025	22472163	All authors	2	participated in the design of the study and manuscript preparation	participated in the design of the study and manuscript preparation	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3352025	22472163	GAG	2	performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
5123318	27884110	GC	2	provided critical inputs to the study and was involved in the drafting of the manuscript	provided critical inputs to the study and was involved in the drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
5123318	27884110	IM	2	participated in the study design, carried out laboratory work, performed the bioinformatic analysis and drafted the manuscript	participated in the study design, carried out laboratory work, performed the bioinformatic analysis and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5123318	27884110	JVDA	2	conceived and supervised the study and helped in the drafting of the manuscript	conceived and supervised the study and helped in the drafting of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Supervision|Writing - Original Draft	YES
3479377	22782438	B.P.	1	Study design	Study design	Conceived and designed the experiments	Methodology	YES
3479377	22782438	C.H.	1	Study design	Study design	Conceived and designed the experiments	Methodology	YES
3479377	22782438	J.C.	1	Guarantor for the entire manuscript|Study design|Principally responsible for manuscript writing	Guarantor for the entire manuscript	-	-	NO
3479377	22782438	J.C.	1	Guarantor for the entire manuscript|Study design|Principally responsible for manuscript writing	Study design	Conceived and designed the experiments	Methodology	YES
3479377	22782438	J.C.	1	Guarantor for the entire manuscript|Study design|Principally responsible for manuscript writing	Principally responsible for manuscript writing	Wrote the paper	Writing - Original Draft	YES
3479377	22782438	M.P.	1	Study design	Study design	Conceived and designed the experiments	Methodology	YES
3479377	22782438	P.G.	1	Study design	Study design	Conceived and designed the experiments	Methodology	YES
3479377	22782438	all authors	1	Critically reviewed/revised manuscript for all content|Approved final version of the submitted manuscript	Critically reviewed/revised manuscript for all content	Wrote the paper	Writing - Review & Editing	YES
3479377	22782438	all authors	1	Critically reviewed/revised manuscript for all content|Approved final version of the submitted manuscript	Approved final version of the submitted manuscript	-	-	NO
6106047	30085685	All authors	2	have given approval to the final version of the manuscript	have given approval to the final version of the manuscript	-	-	NO
4401729	25885271	AZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401729	25885271	AZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401729	25885271	AZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401729	25885271	JBE	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401729	25885271	JBE	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401729	25885271	JBE	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401729	25885271	JFG	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401729	25885271	JK	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4401729	25885271	JK	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401729	25885271	TB	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5487591	28702046	All authors	2	discussed and commented on the manuscript	discussed and commented on the manuscript	-	-	NO
5487591	28702046	JW	2	performed the qrt-pcr experiments and led the overall data analysis	performed the qrt-pcr experiments and led the overall data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5487591	28702046	ML	2	designed the primers and performed the qrt pcr	designed the primers and performed the qrt pcr	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5487591	28702046	TL	2	managed and organized the experimental studies	managed and organized the experimental studies	-	Project administration	YES
5487591	28702046	TZ	2	directed the abiotic stress treatments	directed the abiotic stress treatments	-	Supervision	YES
5487591	28702046	XQ	2	directed the abiotic stress treatments	directed the abiotic stress treatments	-	Supervision	YES
5487591	28702046	ZW	2	revised it	revised it	Wrote the paper	Writing - Review & Editing	YES
3403909	22606951	AAR	2	contributed significantly in the design, manuscript writing and review|conceived and designed the study, collected data in the field, performed the data analysis, interpreted the data, and drafted the manuscript and critically reviewed it	contributed significantly in the design, manuscript writing and review	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3403909	22606951	AAR	2	contributed significantly in the design, manuscript writing and review|conceived and designed the study, collected data in the field, performed the data analysis, interpreted the data, and drafted the manuscript and critically reviewed it	conceived and designed the study, collected data in the field, performed the data analysis, interpreted the data, and drafted the manuscript and critically reviewed it	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
3403909	22606951	SB	2	contributed significantly in the design, manuscript writing and review	contributed significantly in the design, manuscript writing and review	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3403909	22606951	TD	2	was significantly involved in data collection and has reviewed the manuscript	was significantly involved in data collection and has reviewed the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5123343	28185571	MN	2	further improved upon the algorithm|designed the experimental study|ran the experimental study|analyzed the experimental results|wrote the manuscript	further improved upon the algorithm	Contributed reagents/materials/analysis tools	Software	YES
5123343	28185571	MN	2	further improved upon the algorithm|designed the experimental study|ran the experimental study|analyzed the experimental results|wrote the manuscript	designed the experimental study	Conceived and designed the experiments	Methodology	YES
5123343	28185571	MN	2	further improved upon the algorithm|designed the experimental study|ran the experimental study|analyzed the experimental results|wrote the manuscript	ran the experimental study	Performed the experiments	Investigation	YES
5123343	28185571	MN	2	further improved upon the algorithm|designed the experimental study|ran the experimental study|analyzed the experimental results|wrote the manuscript	analyzed the experimental results	Analyzed the data	Formal analysis	YES
5123343	28185571	MN	2	further improved upon the algorithm|designed the experimental study|ran the experimental study|analyzed the experimental results|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5123343	28185571	NN	2	further improved upon the algorithm|implemented hippi|designed the experimental study|ran the experimental study|analyzed the experimental results|wrote the manuscript	further improved upon the algorithm	Contributed reagents/materials/analysis tools	Software	YES
5123343	28185571	NN	2	further improved upon the algorithm|implemented hippi|designed the experimental study|ran the experimental study|analyzed the experimental results|wrote the manuscript	implemented hippi	Performed the experiments	Investigation	YES
5123343	28185571	NN	2	further improved upon the algorithm|implemented hippi|designed the experimental study|ran the experimental study|analyzed the experimental results|wrote the manuscript	designed the experimental study	Conceived and designed the experiments	Methodology	YES
5123343	28185571	NN	2	further improved upon the algorithm|implemented hippi|designed the experimental study|ran the experimental study|analyzed the experimental results|wrote the manuscript	ran the experimental study	Performed the experiments	Investigation	YES
5123343	28185571	NN	2	further improved upon the algorithm|implemented hippi|designed the experimental study|ran the experimental study|analyzed the experimental results|wrote the manuscript	analyzed the experimental results	Analyzed the data	Formal analysis	YES
5123343	28185571	NN	2	further improved upon the algorithm|implemented hippi|designed the experimental study|ran the experimental study|analyzed the experimental results|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5123343	28185571	SM	2	further improved upon the algorithm|designed the experimental study|analyzed the experimental results	further improved upon the algorithm	Contributed reagents/materials/analysis tools	Software	YES
5123343	28185571	SM	2	further improved upon the algorithm|designed the experimental study|analyzed the experimental results	designed the experimental study	Conceived and designed the experiments	Methodology	YES
5123343	28185571	SM	2	further improved upon the algorithm|designed the experimental study|analyzed the experimental results	analyzed the experimental results	Analyzed the data	Formal analysis	YES
5123343	28185571	TW	2	further improved upon the algorithm|designed the experimental study|analyzed the experimental results|wrote the manuscript	further improved upon the algorithm	Contributed reagents/materials/analysis tools	Software	YES
5123343	28185571	TW	2	further improved upon the algorithm|designed the experimental study|analyzed the experimental results|wrote the manuscript	designed the experimental study	Conceived and designed the experiments	Methodology	YES
5123343	28185571	TW	2	further improved upon the algorithm|designed the experimental study|analyzed the experimental results|wrote the manuscript	analyzed the experimental results	Analyzed the data	Formal analysis	YES
5123343	28185571	TW	2	further improved upon the algorithm|designed the experimental study|analyzed the experimental results|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4002152	24758379	J.L.	2	contributed equally to this work	contributed equally to this work	-	-	NO
4002152	24758379	P.H.	2	contributed equally to this work	contributed equally to this work	-	-	NO
4002152	24758379	S.C.	2	contributed equally to this work	contributed equally to this work	-	-	NO
4002152	24758379	Y.Y.	2	contributed equally to this work	contributed equally to this work	-	-	NO
4401730	25886023	DR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401730	25886023	DR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4401730	25886023	DR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401730	25886023	FM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401730	25886023	FM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4401730	25886023	FM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401730	25886023	JFR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401730	25886023	JFR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401730	25886023	JFR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401730	25886023	JFR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401730	25886023	TG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401730	25886023	TG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4401730	25886023	TG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
3409064	22703595	CT	1	Study concept and design|Acquisition of data|Analysis and interpretation of data	Study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
3409064	22703595	CT	1	Study concept and design|Acquisition of data|Analysis and interpretation of data	Acquisition of data	Performed the experiments	Investigation	YES
3409064	22703595	CT	1	Study concept and design|Acquisition of data|Analysis and interpretation of data	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
3409064	22703595	DM	1	Study concept and design|Acquisition of data|Analysis and interpretation of data	Study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
3409064	22703595	DM	1	Study concept and design|Acquisition of data|Analysis and interpretation of data	Acquisition of data	Performed the experiments	Investigation	YES
3409064	22703595	DM	1	Study concept and design|Acquisition of data|Analysis and interpretation of data	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
3409064	22703595	EF	1	Acquisition of data|Analysis and interpretation of data|Critical revision of the manuscript for important intellectual content	Acquisition of data	Performed the experiments	Investigation	YES
3409064	22703595	EF	1	Acquisition of data|Analysis and interpretation of data|Critical revision of the manuscript for important intellectual content	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
3409064	22703595	EF	1	Acquisition of data|Analysis and interpretation of data|Critical revision of the manuscript for important intellectual content	Critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
3409064	22703595	FC	1	Acquisition of data|Critical revision of the manuscript for important intellectual content	Acquisition of data	Performed the experiments	Investigation	YES
3409064	22703595	FC	1	Acquisition of data|Critical revision of the manuscript for important intellectual content	Critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
3409064	22703595	FM	1	Acquisition of data|Critical revision of the manuscript for important intellectual content	Acquisition of data	Performed the experiments	Investigation	YES
3409064	22703595	FM	1	Acquisition of data|Critical revision of the manuscript for important intellectual content	Critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
3409064	22703595	GC	1	Acquisition of data|Critical revision of the manuscript for important intellectual content	Acquisition of data	Performed the experiments	Investigation	YES
3409064	22703595	GC	1	Acquisition of data|Critical revision of the manuscript for important intellectual content	Critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
3409064	22703595	LS	1	Acquisition of data|Critical revision of the manuscript for important intellectual content	Acquisition of data	Performed the experiments	Investigation	YES
3409064	22703595	LS	1	Acquisition of data|Critical revision of the manuscript for important intellectual content	Critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
3409064	22703595	MDP	1	Acquisition of data|Critical revision of the manuscript for important intellectual content	Acquisition of data	Performed the experiments	Investigation	YES
3409064	22703595	MDP	1	Acquisition of data|Critical revision of the manuscript for important intellectual content	Critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
3409064	22703595	MF	1	Acquisition of data|Critical revision of the manuscript for important intellectual content	Acquisition of data	Performed the experiments	Investigation	YES
3409064	22703595	MF	1	Acquisition of data|Critical revision of the manuscript for important intellectual content	Critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
3409064	22703595	NB	1	Study concept and design|Acquisition of data|Analysis and interpretation of data	Study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
3409064	22703595	NB	1	Study concept and design|Acquisition of data|Analysis and interpretation of data	Acquisition of data	Performed the experiments	Investigation	YES
3409064	22703595	NB	1	Study concept and design|Acquisition of data|Analysis and interpretation of data	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
3409064	22703595	NL	1	Acquisition of data|Critical revision of the manuscript for important intellectual content	Acquisition of data	Performed the experiments	Investigation	YES
3409064	22703595	NL	1	Acquisition of data|Critical revision of the manuscript for important intellectual content	Critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
3409064	22703595	PN	1	Acquisition of data|Critical revision of the manuscript for important intellectual content	Acquisition of data	Performed the experiments	Investigation	YES
3409064	22703595	PN	1	Acquisition of data|Critical revision of the manuscript for important intellectual content	Critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
3409064	22703595	SC	1	Acquisition of data|Critical revision of the manuscript for important intellectual content	Acquisition of data	Performed the experiments	Investigation	YES
3409064	22703595	SC	1	Acquisition of data|Critical revision of the manuscript for important intellectual content	Critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
3409064	22703595	SDG	1	Acquisition of data|Critical revision of the manuscript for important intellectual content	Acquisition of data	Performed the experiments	Investigation	YES
3409064	22703595	SDG	1	Acquisition of data|Critical revision of the manuscript for important intellectual content	Critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5487767	28702034	LQ	PLoS52	designed the study|performed the experiments	designed the study	Conceived and designed the experiments	Methodology	YES
5487767	28702034	LQ	PLoS52	designed the study|performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5487767	28702034	NM	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5487767	28702034	YL	PLoS52	designed the study|gave the final approval of the version	designed the study	Conceived and designed the experiments	Methodology	YES
5487767	28702034	YL	PLoS52	designed the study|gave the final approval of the version	gave the final approval of the version	-	-	NO
5487767	28702034	YangZ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
6106049	29446931	All authors	2	have given approval to the final version of the manuscript	have given approval to the final version of the manuscript	-	-	NO
5123380	28185556	KJL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5123380	28185556	KJL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5123380	28185556	KJL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5123380	28185556	ZWW	PLoS5	Conceived and designed the experiments|Implemented scripts for analyses and performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5123380	28185556	ZWW	PLoS5	Conceived and designed the experiments|Implemented scripts for analyses and performed the experiments|Analyzed the data|Wrote the paper	Implemented scripts for analyses and performed the experiments	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5123380	28185556	ZWW	PLoS5	Conceived and designed the experiments|Implemented scripts for analyses and performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5123380	28185556	ZWW	PLoS5	Conceived and designed the experiments|Implemented scripts for analyses and performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4484509	26137534	KA	PLoS5	Designed the study|Performed the autopsy and collected the patients samples|Performed the experiments|Performed the literature search, the comprehensive data analysis and the data interpretation|Wrote the paper	Designed the study	Conceived and designed the experiments	Methodology	YES
4484509	26137534	KA	PLoS5	Designed the study|Performed the autopsy and collected the patients samples|Performed the experiments|Performed the literature search, the comprehensive data analysis and the data interpretation|Wrote the paper	Performed the autopsy and collected the patients samples	Performed the experiments	Investigation	YES
4484509	26137534	KA	PLoS5	Designed the study|Performed the autopsy and collected the patients samples|Performed the experiments|Performed the literature search, the comprehensive data analysis and the data interpretation|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4484509	26137534	KA	PLoS5	Designed the study|Performed the autopsy and collected the patients samples|Performed the experiments|Performed the literature search, the comprehensive data analysis and the data interpretation|Wrote the paper	Performed the literature search, the comprehensive data analysis and the data interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4484509	26137534	KA	PLoS5	Designed the study|Performed the autopsy and collected the patients samples|Performed the experiments|Performed the literature search, the comprehensive data analysis and the data interpretation|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4484509	26137534	TVN	PLoS5	Designed the study|Performed the autopsy and collected the patients samples|Performed the experiments	Designed the study	Conceived and designed the experiments	Methodology	YES
4484509	26137534	TVN	PLoS5	Designed the study|Performed the autopsy and collected the patients samples|Performed the experiments	Performed the autopsy and collected the patients samples	Performed the experiments	Investigation	YES
4484509	26137534	TVN	PLoS5	Designed the study|Performed the autopsy and collected the patients samples|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4484509	26137534	VHP	PLoS5	Designed the study|Performed the experiments	Designed the study	Conceived and designed the experiments	Methodology	YES
4484509	26137534	VHP	PLoS5	Designed the study|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5415947	28480041	A-FS	1	Substantial contributions to study conception/design, or acquisition/analysis/interpretation of data|Drafting of publication, or revising it critically for important intellectual content|Publication	Substantial contributions to study conception/design, or acquisition/analysis/interpretation of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Methodology|Resources	YES
5415947	28480041	A-FS	1	Substantial contributions to study conception/design, or acquisition/analysis/interpretation of data|Drafting of publication, or revising it critically for important intellectual content|Publication	Drafting of publication, or revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5415947	28480041	A-FS	1	Substantial contributions to study conception/design, or acquisition/analysis/interpretation of data|Drafting of publication, or revising it critically for important intellectual content|Publication	Publication	-	-	NO
5415947	28480041	AC	1	Substantial contributions to study conception/design, or acquisition/analysis/interpretation of data|Drafting of publication, or revising it critically for important intellectual content|Publication	Substantial contributions to study conception/design, or acquisition/analysis/interpretation of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Methodology|Resources	YES
5415947	28480041	AC	1	Substantial contributions to study conception/design, or acquisition/analysis/interpretation of data|Drafting of publication, or revising it critically for important intellectual content|Publication	Drafting of publication, or revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5415947	28480041	AC	1	Substantial contributions to study conception/design, or acquisition/analysis/interpretation of data|Drafting of publication, or revising it critically for important intellectual content|Publication	Publication	-	-	NO
5415947	28480041	AD	1	Substantial contributions to study conception/design, or acquisition/analysis/interpretation of data|Drafting of publication, or revising it critically for important intellectual content|Publication	Substantial contributions to study conception/design, or acquisition/analysis/interpretation of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Methodology|Resources	YES
5415947	28480041	AD	1	Substantial contributions to study conception/design, or acquisition/analysis/interpretation of data|Drafting of publication, or revising it critically for important intellectual content|Publication	Drafting of publication, or revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5415947	28480041	AD	1	Substantial contributions to study conception/design, or acquisition/analysis/interpretation of data|Drafting of publication, or revising it critically for important intellectual content|Publication	Publication	-	-	NO
5415947	28480041	BC	1	Substantial contributions to study conception/design, or acquisition/analysis/interpretation of data|Drafting of publication, or revising it critically for important intellectual content|Publication	Substantial contributions to study conception/design, or acquisition/analysis/interpretation of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Methodology|Resources	YES
5415947	28480041	BC	1	Substantial contributions to study conception/design, or acquisition/analysis/interpretation of data|Drafting of publication, or revising it critically for important intellectual content|Publication	Drafting of publication, or revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5415947	28480041	BC	1	Substantial contributions to study conception/design, or acquisition/analysis/interpretation of data|Drafting of publication, or revising it critically for important intellectual content|Publication	Publication	-	-	NO
5415947	28480041	CP	1	Substantial contributions to study conception/design, or acquisition/analysis/interpretation of data|Drafting of publication, or revising it critically for important intellectual content|Publication	Substantial contributions to study conception/design, or acquisition/analysis/interpretation of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Methodology|Resources	YES
5415947	28480041	CP	1	Substantial contributions to study conception/design, or acquisition/analysis/interpretation of data|Drafting of publication, or revising it critically for important intellectual content|Publication	Drafting of publication, or revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5415947	28480041	CP	1	Substantial contributions to study conception/design, or acquisition/analysis/interpretation of data|Drafting of publication, or revising it critically for important intellectual content|Publication	Publication	-	-	NO
5415947	28480041	J-PV	1	Substantial contributions to study conception/design, or acquisition/analysis/interpretation of data|Drafting of publication, or revising it critically for important intellectual content|Publication	Substantial contributions to study conception/design, or acquisition/analysis/interpretation of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Methodology|Resources	YES
5415947	28480041	J-PV	1	Substantial contributions to study conception/design, or acquisition/analysis/interpretation of data|Drafting of publication, or revising it critically for important intellectual content|Publication	Drafting of publication, or revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5415947	28480041	J-PV	1	Substantial contributions to study conception/design, or acquisition/analysis/interpretation of data|Drafting of publication, or revising it critically for important intellectual content|Publication	Publication	-	-	NO
5415947	28480041	JB	1	Substantial contributions to study conception/design, or acquisition/analysis/interpretation of data|Drafting of publication, or revising it critically for important intellectual content|Publication	Substantial contributions to study conception/design, or acquisition/analysis/interpretation of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Methodology|Resources	YES
5415947	28480041	JB	1	Substantial contributions to study conception/design, or acquisition/analysis/interpretation of data|Drafting of publication, or revising it critically for important intellectual content|Publication	Drafting of publication, or revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5415947	28480041	JB	1	Substantial contributions to study conception/design, or acquisition/analysis/interpretation of data|Drafting of publication, or revising it critically for important intellectual content|Publication	Publication	-	-	NO
5415947	28480041	LC	1	Substantial contributions to study conception/design, or acquisition/analysis/interpretation of data|Drafting of publication, or revising it critically for important intellectual content|Publication	Substantial contributions to study conception/design, or acquisition/analysis/interpretation of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Methodology|Resources	YES
5415947	28480041	LC	1	Substantial contributions to study conception/design, or acquisition/analysis/interpretation of data|Drafting of publication, or revising it critically for important intellectual content|Publication	Drafting of publication, or revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5415947	28480041	LC	1	Substantial contributions to study conception/design, or acquisition/analysis/interpretation of data|Drafting of publication, or revising it critically for important intellectual content|Publication	Publication	-	-	NO
5415947	28480041	RB	1	Substantial contributions to study conception/design, or acquisition/analysis/interpretation of data|Drafting of publication, or revising it critically for important intellectual content|Publication	Substantial contributions to study conception/design, or acquisition/analysis/interpretation of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Methodology|Resources	YES
5415947	28480041	RB	1	Substantial contributions to study conception/design, or acquisition/analysis/interpretation of data|Drafting of publication, or revising it critically for important intellectual content|Publication	Drafting of publication, or revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5415947	28480041	RB	1	Substantial contributions to study conception/design, or acquisition/analysis/interpretation of data|Drafting of publication, or revising it critically for important intellectual content|Publication	Publication	-	-	NO
5415947	28480041	VSS	1	Substantial contributions to study conception/design, or acquisition/analysis/interpretation of data|Drafting of publication, or revising it critically for important intellectual content|Publication	Substantial contributions to study conception/design, or acquisition/analysis/interpretation of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Methodology|Resources	YES
5415947	28480041	VSS	1	Substantial contributions to study conception/design, or acquisition/analysis/interpretation of data|Drafting of publication, or revising it critically for important intellectual content|Publication	Drafting of publication, or revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5415947	28480041	VSS	1	Substantial contributions to study conception/design, or acquisition/analysis/interpretation of data|Drafting of publication, or revising it critically for important intellectual content|Publication	Publication	-	-	NO
4401731	25884401	AS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401731	25884401	AS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401731	25884401	AS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401731	25884401	BD	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401731	25884401	GL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401731	25884401	J. Wang	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401731	25884401	J. Wang	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401731	25884401	J. Wang	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401731	25884401	J. Wu	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401731	25884401	JT	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401731	25884401	JT	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401731	25884401	JT	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401731	25884401	JX	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401731	25884401	JXS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401731	25884401	JXS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401731	25884401	JXS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401731	25884401	JXS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401731	25884401	MH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401731	25884401	MJ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401731	25884401	RM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401731	25884401	XW	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
3439243	22897817	DTT	7	Laboratory analysis and have given final approval of the version to be published	Laboratory analysis and have given final approval of the version to be published	Performed the experiments	Investigation	YES
3439243	22897817	HFLW	7	conception and design, acquisition of data, interpretation of data, revising it critically for important intellectual content and have given final approval of the version to be published	conception and design, acquisition of data, interpretation of data, revising it critically for important intellectual content and have given final approval of the version to be published	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Review & Editing	YES
3439243	22897817	ML	7	Analysis and interpretation of data, has been involved in drafting the manuscript and have given final approval of the version to be published	Analysis and interpretation of data, has been involved in drafting the manuscript and have given final approval of the version to be published	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3439243	22897817	NTLH	7	conception and design, acquisition of data, analysis and interpretation of data, has been involved in drafting the manuscript and have given final approval of the version to be published	conception and design, acquisition of data, analysis and interpretation of data, has been involved in drafting the manuscript and have given final approval of the version to be published	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
3439243	22897817	NTMH	7	Acquisition of data and have given final approval of the version to be published	Acquisition of data and have given final approval of the version to be published	Performed the experiments	Investigation	YES
3439243	22897817	NVK	7	conception and design, acquisition of data and have given final approval of the version to be published	conception and design, acquisition of data and have given final approval of the version to be published	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
3439243	22897817	TL	7	Revising it critically for important intellectual content and have given final approval of the version to be published	Revising it critically for important intellectual content and have given final approval of the version to be published	Wrote the paper	Writing - Review & Editing	YES
3439243	22897817	WT	7	conception and design, acquisition of data, revising it critically for important intellectual content and have given final approval of the version to be published. PH -conception and design, acquisition of data, interpretation of data, revising it critically for important intellectual content and have given final approval of the version to be published. NVT- Laboratory analysis and have given final approval of the version to be published	conception and design, acquisition of data, revising it critically for important intellectual content and have given final approval of the version to be published. PH -conception and design, acquisition of data, interpretation of data, revising it critically for important intellectual content and have given final approval of the version to be published. NVT- Laboratory analysis and have given final approval of the version to be published	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Review & Editing	YES
5123390	28185557	All the authors	2	have participated in the conception of the algorithms, the conception of the experiments, the analysis of the results and the writing of the paper	have participated in the conception of the algorithms, the conception of the experiments, the analysis of the results and the writing of the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Software|Writing - Original Draft	YES
5123390	28185557	OT-S	2	implemented the algorithms|realized the experiments	implemented the algorithms	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5123390	28185557	OT-S	2	implemented the algorithms|realized the experiments	realized the experiments	-	-	NO
5123390	28185557	VR	2	implemented the simulated data generator|realized the experiments	implemented the simulated data generator	Performed the experiments	Formal analysis|Investigation	YES
5123390	28185557	VR	2	implemented the simulated data generator|realized the experiments	realized the experiments	-	-	NO
5487829	28702038	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5487829	28702038	DC	2	conceived the study|wrote the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5487829	28702038	DC	2	conceived the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5487829	28702038	DL	2	carried out the plant experiment	carried out the plant experiment	Performed the experiments	Investigation	YES
5487829	28702038	EG	2	carried out the plant experiment|analyzed the generated results	carried out the plant experiment	Performed the experiments	Investigation	YES
5487829	28702038	EG	2	carried out the plant experiment|analyzed the generated results	analyzed the generated results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5487829	28702038	KB	2	conceived the study|carried out the plant experiment	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5487829	28702038	KB	2	conceived the study|carried out the plant experiment	carried out the plant experiment	Performed the experiments	Investigation	YES
5487829	28702038	MM	2	carried out the computational analysis|conducted the rt-qpcr experiments|wrote the manuscript	carried out the computational analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5487829	28702038	MM	2	carried out the computational analysis|conducted the rt-qpcr experiments|wrote the manuscript	conducted the rt-qpcr experiments	Performed the experiments	Investigation	YES
5487829	28702038	MM	2	carried out the computational analysis|conducted the rt-qpcr experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5487829	28702038	QS	2	carried out the microscopy	carried out the microscopy	Performed the experiments	Investigation	YES
5487829	28702038	RF	2	performed the rna extraction and rna seq libraries	performed the rna extraction and rna seq libraries	Performed the experiments	Investigation	YES
5487829	28702038	SM	2	conducted the rt-qpcr experiments	conducted the rt-qpcr experiments	Performed the experiments	Investigation	YES
4484511	26137541	All authors	2	contributed to the refinement of the study report and approved the final version	contributed to the refinement of the study report and approved the final version	-	-	NO
4484511	26137541	EWZ	2	did the statistical analysis	did the statistical analysis	Analyzed the data	Formal analysis	YES
4484511	26137541	MCH	2	developed the mlpa probes and made them available|supervised laboratory analysis	developed the mlpa probes and made them available	-	-	NO
4484511	26137541	MCH	2	developed the mlpa probes and made them available|supervised laboratory analysis	supervised laboratory analysis	Performed the experiments	Investigation|Supervision	YES
4484511	26137541	MFSL	2	undertook, supervised, or monitored the study	undertook, supervised, or monitored the study	Performed the experiments	Investigation|Supervision	YES
4484511	26137541	MS	2	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4484511	26137541	MWB	2	conceived and designed the study|undertook, supervised, or monitored the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4484511	26137541	MWB	2	conceived and designed the study|undertook, supervised, or monitored the study	undertook, supervised, or monitored the study	Performed the experiments	Investigation|Supervision	YES
4484511	26137541	RS	2	conceived and designed the study|undertook, supervised, or monitored the study|obtained and analyzed the data|interpreted the data, designed figures and drafted the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4484511	26137541	RS	2	conceived and designed the study|undertook, supervised, or monitored the study|obtained and analyzed the data|interpreted the data, designed figures and drafted the manuscript	undertook, supervised, or monitored the study	Performed the experiments	Investigation|Supervision	YES
4484511	26137541	RS	2	conceived and designed the study|undertook, supervised, or monitored the study|obtained and analyzed the data|interpreted the data, designed figures and drafted the manuscript	obtained and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4484511	26137541	RS	2	conceived and designed the study|undertook, supervised, or monitored the study|obtained and analyzed the data|interpreted the data, designed figures and drafted the manuscript	interpreted the data, designed figures and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Visualization|Writing - Original Draft	YES
4484511	26137541	SAJ	2	conceived and designed the study|supervised laboratory analysis|undertook, supervised, or monitored the study|obtained and analyzed the data|interpreted the data, designed figures and drafted the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4484511	26137541	SAJ	2	conceived and designed the study|supervised laboratory analysis|undertook, supervised, or monitored the study|obtained and analyzed the data|interpreted the data, designed figures and drafted the manuscript	supervised laboratory analysis	Performed the experiments	Investigation|Supervision	YES
4484511	26137541	SAJ	2	conceived and designed the study|supervised laboratory analysis|undertook, supervised, or monitored the study|obtained and analyzed the data|interpreted the data, designed figures and drafted the manuscript	undertook, supervised, or monitored the study	Performed the experiments	Investigation|Supervision	YES
4484511	26137541	SAJ	2	conceived and designed the study|supervised laboratory analysis|undertook, supervised, or monitored the study|obtained and analyzed the data|interpreted the data, designed figures and drafted the manuscript	obtained and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4484511	26137541	SAJ	2	conceived and designed the study|supervised laboratory analysis|undertook, supervised, or monitored the study|obtained and analyzed the data|interpreted the data, designed figures and drafted the manuscript	interpreted the data, designed figures and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Visualization|Writing - Original Draft	YES
4484511	26137541	STK	2	undertook, supervised, or monitored the study	undertook, supervised, or monitored the study	Performed the experiments	Investigation|Supervision	YES
4484511	26137541	THMO	2	conceived and designed the study|undertook, supervised, or monitored the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4484511	26137541	THMO	2	conceived and designed the study|undertook, supervised, or monitored the study	undertook, supervised, or monitored the study	Performed the experiments	Investigation|Supervision	YES
3439255	22554313	ADL	2	collected and annotated the clinical data|also contributed to drafting the manuscript	collected and annotated the clinical data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
3439255	22554313	ADL	2	collected and annotated the clinical data|also contributed to drafting the manuscript	also contributed to drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
3439255	22554313	FI	2	created and implemented procedures for transferring data from clinical databases to the tce xml schema documents	created and implemented procedures for transferring data from clinical databases to the tce xml schema documents	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
3439255	22554313	IP	2	created and implemented procedures for transferring data from clinical databases to the tce xml schema documents	created and implemented procedures for transferring data from clinical databases to the tce xml schema documents	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
3439255	22554313	JG	2	collected and annotated the clinical data	collected and annotated the clinical data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
3439255	22554313	JLB	2	collected and annotated the clinical data	collected and annotated the clinical data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
3439255	22554313	MZ	2	collected and annotated the clinical data|also contributed to drafting the manuscript	collected and annotated the clinical data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
3439255	22554313	MZ	2	collected and annotated the clinical data|also contributed to drafting the manuscript	also contributed to drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
3439255	22554313	RK	2	collected and annotated the clinical data	collected and annotated the clinical data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
3439255	22554313	RWS	2	designed the study and wrote the manuscript	designed the study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3439255	22554313	SYR	2	designed the study and wrote the manuscript|created and implemented procedures for transferring data from clinical databases to the tce xml schema documents	designed the study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3439255	22554313	SYR	2	designed the study and wrote the manuscript|created and implemented procedures for transferring data from clinical databases to the tce xml schema documents	created and implemented procedures for transferring data from clinical databases to the tce xml schema documents	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
3439255	22554313	TFL	2	created and implemented procedures for transferring data from clinical databases to the tce xml schema documents	created and implemented procedures for transferring data from clinical databases to the tce xml schema documents	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
3439255	22554313	WJF	2	collected and annotated the clinical data|also contributed to drafting the manuscript	collected and annotated the clinical data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
3439255	22554313	WJF	2	collected and annotated the clinical data|also contributed to drafting the manuscript	also contributed to drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
3439255	22554313	WT	2	collected and annotated the clinical data	collected and annotated the clinical data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
4401733	25884444	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401733	25884444	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401733	25884444	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401733	25884444	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401733	25884444	JT	PLoS5	Conceived and designed the experiments|Wrote the paper|Reviewed and edited manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401733	25884444	JT	PLoS5	Conceived and designed the experiments|Wrote the paper|Reviewed and edited manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401733	25884444	JT	PLoS5	Conceived and designed the experiments|Wrote the paper|Reviewed and edited manuscript	Reviewed and edited manuscript	Wrote the paper	Writing - Review & Editing	YES
4401733	25884444	PA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Reviewed and edited manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401733	25884444	PA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Reviewed and edited manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4401733	25884444	PA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Reviewed and edited manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4401733	25884444	PA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Reviewed and edited manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401733	25884444	PA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Reviewed and edited manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401733	25884444	PA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Reviewed and edited manuscript	Reviewed and edited manuscript	Wrote the paper	Writing - Review & Editing	YES
6150666	29185723	All authors	2	have given approval to the final version of the manuscript	have given approval to the final version of the manuscript	-	-	NO
5461638	28596843	All authors	2	contributed equally in the design, data collection, and write up of this article	contributed equally in the design, data collection, and write up of this article	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Resources|Writing - Original Draft	YES
5488741	28702039	AA	2	conducted most of the field experiments as well as simulations in this publication as part of his master and doctorate research|was responsible for most of the manuscript preparation and is the lead author	conducted most of the field experiments as well as simulations in this publication as part of his master and doctorate research	Performed the experiments	Formal analysis|Investigation	YES
5488741	28702039	AA	2	conducted most of the field experiments as well as simulations in this publication as part of his master and doctorate research|was responsible for most of the manuscript preparation and is the lead author	was responsible for most of the manuscript preparation and is the lead author	Wrote the paper	Writing - Original Draft	YES
5488741	28702039	AAs	2	major supervisor and he helped in providing major insight into both experimental and simulated outputs|helped in manuscript preparation and provided major input into soil and weather information	major supervisor and he helped in providing major insight into both experimental and simulated outputs	Performed the experiments	Formal analysis|Investigation|Supervision	YES
5488741	28702039	AAs	2	major supervisor and he helped in providing major insight into both experimental and simulated outputs|helped in manuscript preparation and provided major input into soil and weather information	helped in manuscript preparation and provided major input into soil and weather information	Wrote the paper	Writing - Original Draft	YES
5488741	28702039	AK	2	is also a member of the supervisory team|gave major inputs into understanding the outcomes of experimental and modeled output	is also a member of the supervisory team	-	Supervision	YES
5488741	28702039	AK	2	is also a member of the supervisory team|gave major inputs into understanding the outcomes of experimental and modeled output	gave major inputs into understanding the outcomes of experimental and modeled output	Performed the experiments	Methodology	YES
5488741	28702039	AS	2	helped in field management, data analysis, and graphics|also helped in running the tools responsible for generation of genetic coefficients used in the research	helped in field management, data analysis, and graphics	Analyzed the data	Data curation|Formal analysis	YES
5488741	28702039	AS	2	helped in field management, data analysis, and graphics|also helped in running the tools responsible for generation of genetic coefficients used in the research	also helped in running the tools responsible for generation of genetic coefficients used in the research	Performed the experiments	Investigation	YES
5488741	28702039	BA	2	was involved in field management, data collection, soil analysis, and weather data generation and input|was responsible for most of the soil and weather information used in the research	was involved in field management, data collection, soil analysis, and weather data generation and input	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5488741	28702039	BA	2	was involved in field management, data collection, soil analysis, and weather data generation and input|was responsible for most of the soil and weather information used in the research	was responsible for most of the soil and weather information used in the research	-	-	NO
5488741	28702039	IG	2	was also involved in field data collection and generation of simulation runs|also helped in manuscript preparation and generation of graphs	was also involved in field data collection and generation of simulation runs	Performed the experiments	Formal analysis|Investigation	YES
5488741	28702039	IG	2	was also involved in field data collection and generation of simulation runs|also helped in manuscript preparation and generation of graphs	also helped in manuscript preparation and generation of graphs	Wrote the paper	Writing - Original Draft	YES
3443451	22703627	AC	2	wrote the manuscript, designed the study and analyzed the data	wrote the manuscript, designed the study and analyzed the data	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3443451	22703627	HL	2	participated in the design of the study	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
3443451	22703627	KL	2	participated in the collection of data	participated in the collection of data	Performed the experiments	Investigation	YES
3443451	22703627	PC	2	participated in the collection of data and analyzed the data	participated in the collection of data and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3443451	22703627	RL	2	participated in the collection of data	participated in the collection of data	Performed the experiments	Investigation	YES
4401734	25884707	DM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401734	25884707	DM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401734	25884707	DM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401734	25884707	FVA	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401734	25884707	GO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401734	25884707	GO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401734	25884707	GO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401734	25884707	GO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401734	25884707	GS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401734	25884707	GS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401734	25884707	GS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401734	25884707	GS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401734	25884707	KG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401734	25884707	KG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401734	25884707	KG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401734	25884707	LRB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401734	25884707	MKU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401734	25884707	MKU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401734	25884707	MKU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401734	25884707	MKU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401734	25884707	MS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401734	25884707	MS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401734	25884707	MS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5123393	27884102	AMF	2	conceived of the study, and participated in its design and coordination and helped to draft the manuscript	conceived of the study, and participated in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
5123393	27884102	ASCP	2	conceived of the study, and participated in its design and coordination and helped to draft the manuscript	conceived of the study, and participated in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
5123393	27884102	ASMC	2	conceived of the study, and participated in its design and coordination and helped to draft the manuscript	conceived of the study, and participated in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
5123393	27884102	BFO	2	participated in the design of the study and performed the statistical analysis	participated in the design of the study and performed the statistical analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5123393	27884102	BLU	2	carried out the molecular genetic studies, participated in the sequence alignment and drafted the manuscript	carried out the molecular genetic studies, participated in the sequence alignment and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5123393	27884102	CA	2	carried out the molecular genetic studies, participated in the sequence alignment and drafted the manuscript	carried out the molecular genetic studies, participated in the sequence alignment and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5123393	27884102	DFJG	2	carried out the molecular genetic studies, participated in the sequence alignment and drafted the manuscript	carried out the molecular genetic studies, participated in the sequence alignment and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5123393	27884102	DMG	2	participated in the design of the study and performed the statistical analysis	participated in the design of the study and performed the statistical analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5123393	27884102	EP	2	participated in the design of the study and performed the statistical analysis	participated in the design of the study and performed the statistical analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5123393	27884102	FB	2	participated in the design of the study and performed the statistical analysis|conceived of the study, and participated in its design and coordination and helped to draft the manuscript	participated in the design of the study and performed the statistical analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5123393	27884102	FB	2	participated in the design of the study and performed the statistical analysis|conceived of the study, and participated in its design and coordination and helped to draft the manuscript	conceived of the study, and participated in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
5123393	27884102	FLBF	2	participated in the design of the study and performed the statistical analysis	participated in the design of the study and performed the statistical analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5123393	27884102	HLJC	2	participated in the design of the study and performed the statistical analysis	participated in the design of the study and performed the statistical analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5123393	27884102	HNO	2	conceived of the study, and participated in its design and coordination and helped to draft the manuscript	conceived of the study, and participated in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
5123393	27884102	LFM	2	conceived of the study, and participated in its design and coordination and helped to draft the manuscript	conceived of the study, and participated in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
5123393	27884102	LFSF	2	carried out the molecular genetic studies, participated in the sequence alignment and drafted the manuscript	carried out the molecular genetic studies, participated in the sequence alignment and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5123393	27884102	LGA	2	conceived of the study, and participated in its design and coordination and helped to draft the manuscript	conceived of the study, and participated in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
5123393	27884102	LLC	2	conceived of the study, and participated in its design and coordination and helped to draft the manuscript	conceived of the study, and participated in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
5123393	27884102	MPB	2	carried out the molecular genetic studies, participated in the sequence alignment and drafted the manuscript|participated in the sequence alignment|conceived of the study, and participated in its design and coordination and helped to draft the manuscript	carried out the molecular genetic studies, participated in the sequence alignment and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5123393	27884102	MPB	2	carried out the molecular genetic studies, participated in the sequence alignment and drafted the manuscript|participated in the sequence alignment|conceived of the study, and participated in its design and coordination and helped to draft the manuscript	participated in the sequence alignment	Performed the experiments	Investigation	YES
5123393	27884102	MPB	2	carried out the molecular genetic studies, participated in the sequence alignment and drafted the manuscript|participated in the sequence alignment|conceived of the study, and participated in its design and coordination and helped to draft the manuscript	conceived of the study, and participated in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
5123393	27884102	MVAL	2	carried out the molecular genetic studies, participated in the sequence alignment and drafted the manuscript	carried out the molecular genetic studies, participated in the sequence alignment and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5123393	27884102	NBS	2	carried out the molecular genetic studies, participated in the sequence alignment and drafted the manuscript	carried out the molecular genetic studies, participated in the sequence alignment and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5123393	27884102	RE	2	participated in the design of the study and performed the statistical analysis	participated in the design of the study and performed the statistical analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5123393	27884102	RLT	2	participated in the design of the study and performed the statistical analysis	participated in the design of the study and performed the statistical analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5123393	27884102	RMOS	2	conceived of the study, and participated in its design and coordination and helped to draft the manuscript	conceived of the study, and participated in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
5123393	27884102	SD	2	conceived of the study, and participated in its design and coordination and helped to draft the manuscript	conceived of the study, and participated in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
5461640	28596839	Akira Mizuno	2	contributed new reagents or analytic tools	contributed new reagents or analytic tools	Contributed reagents/materials/analysis tools	Resources	YES
5461640	28596839	Anna A. Shabalova	2	performed data analysis	performed data analysis	Analyzed the data	Formal analysis	YES
5461640	28596839	B Salmina	2	conducted experiments	conducted experiments	Performed the experiments	Investigation	YES
5461640	28596839	Haruhiro Higashida	2	participated in research design|performed data analysis	participated in research design	Conceived and designed the experiments	-	YES
5461640	28596839	Haruhiro Higashida	2	participated in research design|performed data analysis	performed data analysis	Analyzed the data	Formal analysis	YES
5461640	28596839	Hiroshi Okamoto	2	conducted experiments	conducted experiments	Performed the experiments	Investigation	YES
5461640	28596839	Olga Lopatina	2	performed data analysis	performed data analysis	Analyzed the data	Formal analysis	YES
5461640	28596839	Satoshi Shuto	2	participated in research design|contributed new reagents or analytic tools	participated in research design	Conceived and designed the experiments	-	YES
5461640	28596839	Satoshi Shuto	2	participated in research design|contributed new reagents or analytic tools	contributed new reagents or analytic tools	Contributed reagents/materials/analysis tools	Resources	YES
5461640	28596839	Shigeru Yokoyama	2	participated in research design	participated in research design	Conceived and designed the experiments	-	YES
5461640	28596839	Stanislav M. Cherepanov	2	participated in research design|contributed new reagents or analytic tools|performed data analysis	participated in research design	Conceived and designed the experiments	-	YES
5461640	28596839	Stanislav M. Cherepanov	2	participated in research design|contributed new reagents or analytic tools|performed data analysis	contributed new reagents or analytic tools	Contributed reagents/materials/analysis tools	Resources	YES
5461640	28596839	Stanislav M. Cherepanov	2	participated in research design|contributed new reagents or analytic tools|performed data analysis	performed data analysis	Analyzed the data	Formal analysis	YES
5461640	28596839	Wataru Ichinose	2	contributed new reagents or analytic tools	contributed new reagents or analytic tools	Contributed reagents/materials/analysis tools	Resources	YES
5461640	28596839	Yasuhiko Yamamoto	2	conducted experiments	conducted experiments	Performed the experiments	Investigation	YES
3468370	22583930	AB	2	was immense in doing the meta-analysis and meta-regression	was immense in doing the meta-analysis and meta-regression	Analyzed the data	Formal analysis	YES
5489561	28706522	AB	2	conceived the idea and designed the experiments|supervised the experimentation|contributed to reviewing and editing the manuscript	conceived the idea and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5489561	28706522	AB	2	conceived the idea and designed the experiments|supervised the experimentation|contributed to reviewing and editing the manuscript	supervised the experimentation	Performed the experiments	Investigation|Supervision	YES
5489561	28706522	AB	2	conceived the idea and designed the experiments|supervised the experimentation|contributed to reviewing and editing the manuscript	contributed to reviewing and editing the manuscript	Wrote the paper	Writing - Review & Editing	YES
5489561	28706522	All authors	2	contributed in interpreting the data	contributed in interpreting the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5489561	28706522	EN	2	contributed to reviewing and editing the manuscript	contributed to reviewing and editing the manuscript	Wrote the paper	Writing - Review & Editing	YES
5489561	28706522	KM	2	conceived the idea and designed the experiments|performed the experiments and wrote the manuscript|contributed to reviewing and editing the manuscript	conceived the idea and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5489561	28706522	KM	2	conceived the idea and designed the experiments|performed the experiments and wrote the manuscript|contributed to reviewing and editing the manuscript	performed the experiments and wrote the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5489561	28706522	KM	2	conceived the idea and designed the experiments|performed the experiments and wrote the manuscript|contributed to reviewing and editing the manuscript	contributed to reviewing and editing the manuscript	Wrote the paper	Writing - Review & Editing	YES
5489561	28706522	LT	2	conceived the idea and designed the experiments|supervised the experimentation|contributed to reviewing and editing the manuscript	conceived the idea and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5489561	28706522	LT	2	conceived the idea and designed the experiments|supervised the experimentation|contributed to reviewing and editing the manuscript	supervised the experimentation	Performed the experiments	Investigation|Supervision	YES
5489561	28706522	LT	2	conceived the idea and designed the experiments|supervised the experimentation|contributed to reviewing and editing the manuscript	contributed to reviewing and editing the manuscript	Wrote the paper	Writing - Review & Editing	YES
5489561	28706522	NA	2	contributed to reviewing and editing the manuscript	contributed to reviewing and editing the manuscript	Wrote the paper	Writing - Review & Editing	YES
5489561	28706522	SC	2	conceived the idea and designed the experiments	conceived the idea and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4450267	26090422	Blanca E. Callejas	2	contributed equally to this work	contributed equally to this work	-	-	NO
4450267	26090422	Yadira Ledesma-Soto	2	contributed equally to this work	contributed equally to this work	-	-	NO
3417195	22919324	D. Baston-Bust	2	has equally contributed to this work	has equally contributed to this work	-	-	NO
3417195	22919324	N. Pfeifer	2	has equally contributed to this work	has equally contributed to this work	-	-	NO
3469338	22709957	GJ	2	designed the study, collected data, wrote the first draft, reviewed manuscript before submission	designed the study, collected data, wrote the first draft, reviewed manuscript before submission	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
3469338	22709957	JA	2	designed the study, collected data, wrote the first draft, reviewed manuscript before submission	designed the study, collected data, wrote the first draft, reviewed manuscript before submission	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
3469338	22709957	KC	2	designed the study, collected data, wrote the first draft, reviewed manuscript before submission	designed the study, collected data, wrote the first draft, reviewed manuscript before submission	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
3469338	22709957	NW	2	collected data, reviewed and commented of manuscript before submission	collected data, reviewed and commented of manuscript before submission	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
3469338	22709957	PK	2	collected data, reviewed and commented of manuscript before submission	collected data, reviewed and commented of manuscript before submission	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
3469338	22709957	PS	2	collected data, reviewed and commented of manuscript before submission	collected data, reviewed and commented of manuscript before submission	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
3469338	22709957	RH	2	collected data, reviewed and commented of manuscript before submission	collected data, reviewed and commented of manuscript before submission	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
3469338	22709957	TP	2	designed the study, collected data, wrote the first draft, reviewed manuscript before submission	designed the study, collected data, wrote the first draft, reviewed manuscript before submission	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
3469338	22709957	TS	2	collected data, reviewed and commented of manuscript before submission	collected data, reviewed and commented of manuscript before submission	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
3469338	22709957	US	2	analyzed, reviewed and commented draft of manuscript before submission	analyzed, reviewed and commented draft of manuscript before submission	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
3469338	22709957	VS	2	collected data, reviewed and commented of manuscript before submission	collected data, reviewed and commented of manuscript before submission	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
3469338	22709957	WP	2	collected data, reviewed and commented of manuscript before submission|collected data, reviewed and commented of manuscript before submission	collected data, reviewed and commented of manuscript before submission	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
3469338	22709957	WP	2	collected data, reviewed and commented of manuscript before submission|collected data, reviewed and commented of manuscript before submission	collected data, reviewed and commented of manuscript before submission	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5461642	28596835	All other authors	2	contributed to editing the manuscript	contributed to editing the manuscript	Wrote the paper	Writing - Review & Editing	YES
5461642	28596835	S.S.	2	collected and analyzed the data|analyzed the affymetrix microarray data|wrote the first and final drafts of the manuscript	collected and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5461642	28596835	S.S.	2	collected and analyzed the data|analyzed the affymetrix microarray data|wrote the first and final drafts of the manuscript	analyzed the affymetrix microarray data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5461642	28596835	S.S.	2	collected and analyzed the data|analyzed the affymetrix microarray data|wrote the first and final drafts of the manuscript	wrote the first and final drafts of the manuscript	Wrote the paper	Writing - Original Draft	YES
5461642	28596835	S.U.	2	organized and directed the study	organized and directed the study	-	Project administration|Supervision	YES
5461642	28596835	T.F.	2	developed the study concept|collected and analyzed the data|wrote the first and final drafts of the manuscript	developed the study concept	Conceived and designed the experiments	Conceptualization	YES
5461642	28596835	T.F.	2	developed the study concept|collected and analyzed the data|wrote the first and final drafts of the manuscript	collected and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5461642	28596835	T.F.	2	developed the study concept|collected and analyzed the data|wrote the first and final drafts of the manuscript	wrote the first and final drafts of the manuscript	Wrote the paper	Writing - Original Draft	YES
5461642	28596835	Y.M.	2	collected and analyzed the data	collected and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4401735	25885446	RL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Derived concepts and theory	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401735	25885446	RL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Derived concepts and theory	Performed the experiments	Performed the experiments	Investigation	YES
4401735	25885446	RL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Derived concepts and theory	Analyzed the data	Analyzed the data	Formal analysis	YES
4401735	25885446	RL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Derived concepts and theory	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401735	25885446	RL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Derived concepts and theory	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401735	25885446	RL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Derived concepts and theory	Derived concepts and theory	Conceived and designed the experiments	Conceptualization	YES
5489589	28706530	CK	PLoS52	planned and designed the research|wrote the paper	planned and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5489589	28706530	CK	PLoS52	planned and designed the research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5489589	28706530	JD	PLoS52	planned and designed the research|performed research	planned and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5489589	28706530	JD	PLoS52	planned and designed the research|performed research	performed research	Performed the experiments	Investigation	YES
5489589	28706530	KL	PLoS52	planned and designed the research|performed research	planned and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5489589	28706530	KL	PLoS52	planned and designed the research|performed research	performed research	Performed the experiments	Investigation	YES
5489589	28706530	RL	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5489589	28706530	SL	PLoS52	analyzed rna seq data	analyzed rna seq data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5489589	28706530	VD	PLoS52	planned and designed the research|performed research|analyzed rna seq data|wrote the paper	planned and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5489589	28706530	VD	PLoS52	planned and designed the research|performed research|analyzed rna seq data|wrote the paper	performed research	Performed the experiments	Investigation	YES
5489589	28706530	VD	PLoS52	planned and designed the research|performed research|analyzed rna seq data|wrote the paper	analyzed rna seq data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5489589	28706530	VD	PLoS52	planned and designed the research|performed research|analyzed rna seq data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5123417	27884105	DYN	2	performed research	performed research	Performed the experiments	Investigation	YES
5123417	27884105	IAI	2	analyzed data and wrote the paper	analyzed data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5123417	27884105	MSP	2	performed research	performed research	Performed the experiments	Investigation	YES
5123417	27884105	MVK	2	performed research	performed research	Performed the experiments	Investigation	YES
5123417	27884105	SLG	2	have given final approval of the version to be published	have given final approval of the version to be published	-	-	NO
5123417	27884105	YDN	2	performed research	performed research	Performed the experiments	Investigation	YES
3472290	22929124	DY	2	carried out all data analyses|interpreted results of statistical testing and made inferences	carried out all data analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3472290	22929124	DY	2	carried out all data analyses|interpreted results of statistical testing and made inferences	interpreted results of statistical testing and made inferences	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3472290	22929124	SLS	2	interpreted results of statistical testing and made inferences	interpreted results of statistical testing and made inferences	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3472290	22929124	SM	2	under the	under the	-	-	NO
3472290	22929124	SS	2	supervised sm under the	supervised sm under the	-	Supervision	YES
4450268	26090434	Haiwei Huang	2	had equal contribution in this paper	had equal contribution in this paper	-	-	NO
4450268	26090434	Hecheng Wang	2	had equal contribution in this paper	had equal contribution in this paper	-	-	NO
4484518	26137535	AdR	2	recruited patients and obtained consent, and carried out the human experimental infection study	recruited patients and obtained consent, and carried out the human experimental infection study	Performed the experiments	Investigation|Project administration	YES
4484518	26137535	BT-T	2	recruited patients and obtained consent, and carried out the human experimental infection study	recruited patients and obtained consent, and carried out the human experimental infection study	Performed the experiments	Investigation|Project administration	YES
4484518	26137535	CC	2	made technical contributions	made technical contributions	-	-	NO
4484518	26137535	DG	2	made technical contributions	made technical contributions	-	-	NO
4484518	26137535	DJJ	2	recruited patients and obtained consent, and carried out the human experimental infection study	recruited patients and obtained consent, and carried out the human experimental infection study	Performed the experiments	Investigation|Project administration	YES
4484518	26137535	KN	2	implemented the study, analysed data, and wrote the report	implemented the study, analysed data, and wrote the report	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4484518	26137535	PM	2	recruited patients and obtained consent, and carried out the human experimental infection study	recruited patients and obtained consent, and carried out the human experimental infection study	Performed the experiments	Investigation|Project administration	YES
4484518	26137535	RV	2	designed the study, interpreted data and wrote the report|were principal investigators and conceived the project	designed the study, interpreted data and wrote the report	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4484518	26137535	RV	2	designed the study, interpreted data and wrote the report|were principal investigators and conceived the project	were principal investigators and conceived the project	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
4484518	26137535	SLJ	2	recruited patients and obtained consent, and carried out the human experimental infection study|were principal investigators and conceived the project	recruited patients and obtained consent, and carried out the human experimental infection study	Performed the experiments	Investigation|Project administration	YES
4484518	26137535	SLJ	2	recruited patients and obtained consent, and carried out the human experimental infection study|were principal investigators and conceived the project	were principal investigators and conceived the project	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
4401736	25884227	EG	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401736	25884227	EG	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401736	25884227	JG	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401736	25884227	JG	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401736	25884227	NH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401736	25884227	NH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4401736	25884227	NH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401736	25884227	NJ	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4401736	25884227	NJ	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401736	25884227	ST	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401736	25884227	ST	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401736	25884227	ST	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401736	25884227	TP	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4401736	25884227	TP	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401736	25884227	WD	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401736	25884227	WD	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
3472320	22853692	AL	2	wrote the hiv reservoirs & search for a cure section|formatted the entire article	wrote the hiv reservoirs & search for a cure section	Wrote the paper	Writing - Original Draft	YES
3472320	22853692	AL	2	wrote the hiv reservoirs & search for a cure section|formatted the entire article	formatted the entire article	-	-	NO
3472320	22853692	HJS	2	wrote the clinical and therapeutic section	wrote the clinical and therapeutic section	Wrote the paper	Writing - Original Draft	YES
3472320	22853692	JI	2	wrote the hiv reservoirs & search for a cure section	wrote the hiv reservoirs & search for a cure section	Wrote the paper	Writing - Original Draft	YES
3472320	22853692	MS	2	wrote the hiv reservoirs & search for a cure section	wrote the hiv reservoirs & search for a cure section	Wrote the paper	Writing - Original Draft	YES
3472320	22853692	MSM	2	wrote the epidemic, prevention and universal access section	wrote the epidemic, prevention and universal access section	Wrote the paper	Writing - Original Draft	YES
3472320	22853692	VS	2	wrote the hepatitis section	wrote the hepatitis section	Wrote the paper	Writing - Original Draft	YES
5124223	27887572	AM	1	Project concept and design	Project concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5124223	27887572	BRJ	1	Data collection	Data collection	Performed the experiments	Investigation	YES
5124223	27887572	DMR	1	Project concept and design	Project concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5124223	27887572	PMU	1	Data collection	Data collection	Performed the experiments	Investigation	YES
5124223	27887572	RMN	1	Data collection	Data collection	Performed the experiments	Investigation	YES
5124223	27887572	SHE	1	Data collection	Data collection	Performed the experiments	Investigation	YES
5124223	27887572	SJL	1	Project concept and design|Data collection	Project concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5124223	27887572	SJL	1	Project concept and design|Data collection	Data collection	Performed the experiments	Investigation	YES
5124223	27887572	WN	1	Data collection	Data collection	Performed the experiments	Investigation	YES
5489591	28706529	CZ	PLoS52	conceived and designed the experiment|performed the experiment|analyzed the data|wrote the paper	conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5489591	28706529	CZ	PLoS52	conceived and designed the experiment|performed the experiment|analyzed the data|wrote the paper	performed the experiment	Performed the experiments	Investigation	YES
5489591	28706529	CZ	PLoS52	conceived and designed the experiment|performed the experiment|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5489591	28706529	CZ	PLoS52	conceived and designed the experiment|performed the experiment|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5489591	28706529	FL	PLoS52	performed the experiment	performed the experiment	Performed the experiments	Investigation	YES
5489591	28706529	JW	PLoS52	conceived and designed the experiment	conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5489591	28706529	LZ	PLoS52	performed the experiment	performed the experiment	Performed the experiments	Investigation	YES
5489591	28706529	XX	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5489591	28706529	YX	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5489591	28706529	ZM	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
3485617	23057423	ACB	2	helped design the analyses, and the aggregated dataset from which they were drawn	helped design the analyses, and the aggregated dataset from which they were drawn	Conceived and designed the experiments|Analyzed the data	Formal analysis	YES
3485617	23057423	All the authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
3485617	23057423	HHL	2	conducted the statistical analyses	conducted the statistical analyses	Analyzed the data	Formal analysis	YES
3485617	23057423	MR	2	designed the analyses and drafted the manuscript	designed the analyses and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3485617	23057423	YW	2	conducted the statistical analyses	conducted the statistical analyses	Analyzed the data	Formal analysis	YES
4401737	25885705	DW	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401737	25885705	LC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401737	25885705	XZ	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401737	25885705	YT	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401737	25885705	YY	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5461645	28596837	Atsushi Fujita	1	Conducted experiments	Conducted experiments	Performed the experiments	Investigation	YES
5461645	28596837	Hidehiko Narazaki	1	Conducted experiments	Conducted experiments	Performed the experiments	Investigation	YES
5461645	28596837	Takeshi Asano	1	Participated in research design|Conducted experiments|Contributed new reagents or analytic tools|Performed data analysis|Wrote or contributed to the writing of the manuscript	Participated in research design	Conceived and designed the experiments	-	YES
5461645	28596837	Takeshi Asano	1	Participated in research design|Conducted experiments|Contributed new reagents or analytic tools|Performed data analysis|Wrote or contributed to the writing of the manuscript	Conducted experiments	Performed the experiments	Investigation	YES
5461645	28596837	Takeshi Asano	1	Participated in research design|Conducted experiments|Contributed new reagents or analytic tools|Performed data analysis|Wrote or contributed to the writing of the manuscript	Contributed new reagents or analytic tools	Contributed reagents/materials/analysis tools	Resources	YES
5461645	28596837	Takeshi Asano	1	Participated in research design|Conducted experiments|Contributed new reagents or analytic tools|Performed data analysis|Wrote or contributed to the writing of the manuscript	Performed data analysis	Analyzed the data	Formal analysis	YES
5461645	28596837	Takeshi Asano	1	Participated in research design|Conducted experiments|Contributed new reagents or analytic tools|Performed data analysis|Wrote or contributed to the writing of the manuscript	Wrote or contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
4484814	26137553	ALA	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
4484814	26137553	DO	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
4484814	26137553	JA	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
4484814	26137553	JMD	PLoS52	generated the mbactgdyrk1a mouse model	generated the mbactgdyrk1a mouse model	Performed the experiments	Investigation|Methodology	YES
4484814	26137553	MJB	PLoS52	designed the experiments and analysed the data|interpreted the data	designed the experiments and analysed the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
4484814	26137553	MJB	PLoS52	designed the experiments and analysed the data|interpreted the data	interpreted the data	Analyzed the data	Formal analysis	YES
4484814	26137553	MLA	PLoS52	conceived the project|wrote the manuscript	conceived the project	Conceived and designed the experiments	Conceptualization	YES
4484814	26137553	MLA	PLoS52	conceived the project|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4484814	26137553	PAL	PLoS52	designed the experiments and analysed the data|performed the experiments	designed the experiments and analysed the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
4484814	26137553	PAL	PLoS52	designed the experiments and analysed the data|performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
4484814	26137553	SJC	PLoS52	designed the experiments and analysed the data|interpreted the data	designed the experiments and analysed the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
4484814	26137553	SJC	PLoS52	designed the experiments and analysed the data|interpreted the data	interpreted the data	Analyzed the data	Formal analysis	YES
4484814	26137553	SN	PLoS52	designed the experiments and analysed the data|performed the experiments|interpreted the data	designed the experiments and analysed the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
4484814	26137553	SN	PLoS52	designed the experiments and analysed the data|performed the experiments|interpreted the data	performed the experiments	Performed the experiments	Investigation	YES
4484814	26137553	SN	PLoS52	designed the experiments and analysed the data|performed the experiments|interpreted the data	interpreted the data	Analyzed the data	Formal analysis	YES
5124300	27887573	CK	2	was involved in the revision of the manuscript and provided technical advices and support for the molecular experiments	was involved in the revision of the manuscript and provided technical advices and support for the molecular experiments	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5124300	27887573	DO	2	carried out the functional characterization studies, participated in bioinformatics analysis and drafted the manuscript	carried out the functional characterization studies, participated in bioinformatics analysis and drafted the manuscript	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5124300	27887573	KY	2	participated in the collection of genetic material from patients and provided guidance in the drafting of the manuscript	participated in the collection of genetic material from patients and provided guidance in the drafting of the manuscript	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Original Draft	YES
5124300	27887573	SG	2	carried out the functional characterization studies, participated in bioinformatics analysis and drafted the manuscript	carried out the functional characterization studies, participated in bioinformatics analysis and drafted the manuscript	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5124300	27887573	YS	2	provided technical advices and support for the molecular experiments, participated in the drafting and revision of manuscript	provided technical advices and support for the molecular experiments, participated in the drafting and revision of manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5489598	28706527	JL	PLoS52	sampled the material and contributed to sphingolipid and sterol analysis	sampled the material and contributed to sphingolipid and sterol analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5489598	28706527	MG-J	PLoS52	conceived and supervised the study, wrote and critically revised the manuscript	conceived and supervised the study, wrote and critically revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
5489598	28706527	MG-R	PLoS52	contributed to analyze and discuss the results and prepare the manuscript	contributed to analyze and discuss the results and prepare the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5489598	28706527	MP	PLoS52	sampled the material and contributed to sphingolipid and sterol analysis	sampled the material and contributed to sphingolipid and sterol analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5489598	28706527	MP-L	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5489598	28706527	MS-G	PLoS52	contributed to analyze and discuss the results and prepare the manuscript	contributed to analyze and discuss the results and prepare the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3499183	23095661	AT	2	generated and designed the study, performed analysis and interpretation of data including with manuscript drafting	generated and designed the study, performed analysis and interpretation of data including with manuscript drafting	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
3499183	23095661	HA	2	assisted with the design, interpretation of data and the critical appraisal of the manuscript	assisted with the design, interpretation of data and the critical appraisal of the manuscript	Conceived and designed the experiments|Analyzed the data	Formal analysis	YES
3499183	23095661	SB	2	assisted with the design, interpretation of data and the critical appraisal of the manuscript	assisted with the design, interpretation of data and the critical appraisal of the manuscript	Conceived and designed the experiments|Analyzed the data	Formal analysis	YES
3499183	23095661	ZA	2	assisted with the design, interpretation of data and the critical appraisal of the manuscript	assisted with the design, interpretation of data and the critical appraisal of the manuscript	Conceived and designed the experiments|Analyzed the data	Formal analysis	YES
4401738	25885411	GXX	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4401738	25885411	GXX	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4401738	25885411	GXX	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401738	25885411	HTM	PLoS5	Performed statistical work	Performed statistical work	Analyzed the data	Formal analysis	YES
4401738	25885411	HYT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401738	25885411	HYT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401738	25885411	HYT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401738	25885411	HYT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401738	25885411	HYT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401738	25885411	JHW	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401738	25885411	JJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401738	25885411	JJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401738	25885411	JJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401738	25885411	JJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401738	25885411	JJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401738	25885411	LHC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401738	25885411	LHC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401738	25885411	LHC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401738	25885411	LHC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401738	25885411	LHC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401738	25885411	PL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401738	25885411	XYZ	PLoS5	Designed the software used in analysis	Designed the software used in analysis	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
4401738	25885411	YMT	PLoS5	Designed the software used in analysis	Designed the software used in analysis	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
3503578	22998738	BM	7	Execution of the study, data collection and training	Execution of the study, data collection and training	Performed the experiments	Investigation	YES
3503578	22998738	BR	7	Execution and manuscript writing	Execution and manuscript writing	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3503578	22998738	MS	7	Execution and manuscript writing	Execution and manuscript writing	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3503578	22998738	MT	7	Planning, execution, analysis of the data and manuscript writing	Planning, execution, analysis of the data and manuscript writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
3503578	22998738	NS	7	Execution of the study, data collection and training|Execution and manuscript writing	Execution of the study, data collection and training	Performed the experiments	Investigation	YES
3503578	22998738	NS	7	Execution of the study, data collection and training|Execution and manuscript writing	Execution and manuscript writing	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3503578	22998738	PT	7	Execution and manuscript writing	Execution and manuscript writing	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3503578	22998738	RP	7	Planning and manuscript writing	Planning and manuscript writing	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3503578	22998738	SB	7	Execution of the study, data collection and training	Execution of the study, data collection and training	Performed the experiments	Investigation	YES
3503578	22998738	SK	7	Execution and manuscript writing	Execution and manuscript writing	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3503578	22998738	SS	7	statistical analysis	statistical analysis	Analyzed the data	Formal analysis	YES
3417198	22919334	E. Kousi	2	contributed equally to this current study	contributed equally to this current study	-	-	NO
3417198	22919334	I. Tsougos	2	contributed equally to this current study	contributed equally to this current study	-	-	NO
5124311	27887564	AED	PLoS52	conceived the study|designed the study, wrote the paper and all agreed to the submitted version	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5124311	27887564	AED	PLoS52	conceived the study|designed the study, wrote the paper and all agreed to the submitted version	designed the study, wrote the paper and all agreed to the submitted version	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5124311	27887564	AJD	PLoS52	analysed the data|designed the study, wrote the paper and all agreed to the submitted version	analysed the data	Analyzed the data	Formal analysis	YES
5124311	27887564	AJD	PLoS52	analysed the data|designed the study, wrote the paper and all agreed to the submitted version	designed the study, wrote the paper and all agreed to the submitted version	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5124311	27887564	JMC	PLoS52	conducted the rna seq analysis|conceived the study|designed the study, wrote the paper and all agreed to the submitted version	conducted the rna seq analysis	Performed the experiments	Investigation	YES
5124311	27887564	JMC	PLoS52	conducted the rna seq analysis|conceived the study|designed the study, wrote the paper and all agreed to the submitted version	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5124311	27887564	JMC	PLoS52	conducted the rna seq analysis|conceived the study|designed the study, wrote the paper and all agreed to the submitted version	designed the study, wrote the paper and all agreed to the submitted version	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4401739	25885926	QZ	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401739	25885926	XGL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401739	25885926	ZYG	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401739	25885926	ZYG	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401739	25885926	ZYJ	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
3505473	23031736	AJ	2	conceived the idea, edited the manuscript and gave overall support	conceived the idea, edited the manuscript and gave overall support	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
3505473	23031736	FO	2	participated in the clinical care of the patients	participated in the clinical care of the patients	Performed the experiments	Investigation	YES
3505473	23031736	HIV	2	clinical activities, performed the statistical analysis and drafted the manuscript	clinical activities, performed the statistical analysis and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3505473	23031736	KP	2	participated in the clinical care of the patients	participated in the clinical care of the patients	Performed the experiments	Investigation	YES
3505473	23031736	TT	2	contributed to the study design, participated in the statistical analysis and helped to draft the manuscript|participated in the clinical care of the patients	contributed to the study design, participated in the statistical analysis and helped to draft the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3505473	23031736	TT	2	contributed to the study design, participated in the statistical analysis and helped to draft the manuscript|participated in the clinical care of the patients	participated in the clinical care of the patients	Performed the experiments	Investigation	YES
5489599	28706533	BIX	2	treatments, proembryo and embryo quantification	treatments, proembryo and embryo quantification	-	-	NO
5489599	28706533	MR	2	participated in the design of the work and in the discussion of the results	participated in the design of the work and in the discussion of the results	Conceived and designed the experiments	-	YES
5489599	28706533	PT	2	designed and supervised the experimental work, analyzed the results, elaborated the conclusions and wrote the manuscript	designed and supervised the experimental work, analyzed the results, elaborated the conclusions and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Supervision|Writing - Original Draft	YES
5489599	28706533	YP-P	2	performed the quantification of immunofluorescence signal intensities	performed the quantification of immunofluorescence signal intensities	Performed the experiments	Investigation	YES
4484820	26137532	AJR	2	conceived the idea of applying the roc analysis methodology to imaging data|provided advice on the clinical interpretation of findings	conceived the idea of applying the roc analysis methodology to imaging data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology|Visualization	YES
4484820	26137532	AJR	2	conceived the idea of applying the roc analysis methodology to imaging data|provided advice on the clinical interpretation of findings	provided advice on the clinical interpretation of findings	Analyzed the data	Formal analysis	YES
4484820	26137532	All authors	2	provided major edits and advice in the write up of manuscript	provided major edits and advice in the write up of manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4484820	26137532	CB	2	provided expertise on the implementation and interpretation of the roc analyses	provided expertise on the implementation and interpretation of the roc analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4484820	26137532	EG	2	conceived the idea of applying the roc analysis methodology to imaging data|provided advice on the clinical interpretation of findings	conceived the idea of applying the roc analysis methodology to imaging data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology|Visualization	YES
4484820	26137532	EG	2	conceived the idea of applying the roc analysis methodology to imaging data|provided advice on the clinical interpretation of findings	provided advice on the clinical interpretation of findings	Analyzed the data	Formal analysis	YES
4484820	26137532	LMW	2	conceived the idea of applying the roc analysis methodology to imaging data	conceived the idea of applying the roc analysis methodology to imaging data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology|Visualization	YES
4484820	26137532	MSK	2	conceived the idea of applying the roc analysis methodology to imaging data|performed the literature search, imaging data analyses, statistical analysis, and wrote the first draft of the manuscript	conceived the idea of applying the roc analysis methodology to imaging data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology|Visualization	YES
4484820	26137532	MSK	2	conceived the idea of applying the roc analysis methodology to imaging data|performed the literature search, imaging data analyses, statistical analysis, and wrote the first draft of the manuscript	performed the literature search, imaging data analyses, statistical analysis, and wrote the first draft of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Visualization|Writing - Original Draft	YES
4484820	26137532	PI	2	for the sydney site, and led the design of the overall ispot-d study	for the sydney site, and led the design of the overall ispot-d study	Conceived and designed the experiments	Methodology	YES
4484820	26137532	SMG	2	conceived the idea of applying the roc analysis methodology to imaging data|performed the literature search, imaging data analyses, statistical analysis, and wrote the first draft of the manuscript	conceived the idea of applying the roc analysis methodology to imaging data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology|Visualization	YES
4484820	26137532	SMG	2	conceived the idea of applying the roc analysis methodology to imaging data|performed the literature search, imaging data analyses, statistical analysis, and wrote the first draft of the manuscript	performed the literature search, imaging data analyses, statistical analysis, and wrote the first draft of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Visualization|Writing - Original Draft	YES
4484820	26137532	SPOT-D	2	conceived the idea of applying the roc analysis methodology to imaging data	conceived the idea of applying the roc analysis methodology to imaging data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology|Visualization	YES
4484820	26137532	WR	2	provided statistical advice and performed roc analysis of the test cohort	provided statistical advice and performed roc analysis of the test cohort	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5124321	27887567	GTB	2	helped with the designed the study with the	helped with the designed the study with the	Conceived and designed the experiments	Methodology	YES
5124321	27887567	HAA	2	designed the study with the|performed experiments, analysed the data and co-wrote the manuscript	designed the study with the	Conceived and designed the experiments	Methodology	YES
5124321	27887567	HAA	2	designed the study with the|performed experiments, analysed the data and co-wrote the manuscript	performed experiments, analysed the data and co-wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5124321	27887567	NWE	2	isolated the rdna and labelled all the probes for fish|provided major help in improving the manuscript	isolated the rdna and labelled all the probes for fish	Performed the experiments	Investigation	YES
5124321	27887567	NWE	2	isolated the rdna and labelled all the probes for fish|provided major help in improving the manuscript	provided major help in improving the manuscript	Wrote the paper	Writing - Review & Editing	YES
5124321	27887567	SAB	2	prepared genomic and cdna constructs for the lpgi gene to be used as probes for fish	prepared genomic and cdna constructs for the lpgi gene to be used as probes for fish	Performed the experiments	Investigation	YES
5124321	27887567	SWH	2	developed the haploid ryegrass plant and provided it for experimental use	developed the haploid ryegrass plant and provided it for experimental use	Performed the experiments	Investigation	YES
5124321	27887567	WMW	2	helped with the designed the study with the	helped with the designed the study with the	Conceived and designed the experiments	Methodology	YES
6257630	30365308	All authors	2	have given approval to the final version of the manuscript	have given approval to the final version of the manuscript	-	-	NO
4401740	25886464	DM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401740	25886464	DM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401740	25886464	DM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401740	25886464	HH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401740	25886464	HH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401740	25886464	HH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401740	25886464	HH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401740	25886464	IJK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401740	25886464	IJK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401740	25886464	IJK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401740	25886464	MWJJ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401740	25886464	MWJJ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401740	25886464	MWJJ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401740	25886464	NWHJ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401740	25886464	NWHJ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401740	25886464	NWHJ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5489631	28706524	LG	2	revised manuscript for publication	revised manuscript for publication	Wrote the paper	Writing - Review & Editing	YES
5126809	27894274	AO	2	performed the human cell experiments	performed the human cell experiments	Performed the experiments	Investigation	YES
5126809	27894274	HA	2	provided instructions	provided instructions	-	Supervision	YES
5126809	27894274	HI	2	performed the mouse experiments	performed the mouse experiments	Performed the experiments	Investigation	YES
5126809	27894274	KM	2	performed the human cell experiments	performed the human cell experiments	Performed the experiments	Investigation	YES
5126809	27894274	KT	2	wrote the manuscript|supervised the project	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5126809	27894274	KT	2	wrote the manuscript|supervised the project	supervised the project	-	Supervision	YES
5126809	27894274	SN	2	designed all the experiments and analyzed the data|performed the human cell experiments	designed all the experiments and analyzed the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5126809	27894274	SN	2	designed all the experiments and analyzed the data|performed the human cell experiments	performed the human cell experiments	Performed the experiments	Investigation	YES
5126809	27894274	TA	2	conceived the study|wrote the manuscript|designed all the experiments and analyzed the data|performed the mouse experiments	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5126809	27894274	TA	2	conceived the study|wrote the manuscript|designed all the experiments and analyzed the data|performed the mouse experiments	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5126809	27894274	TA	2	conceived the study|wrote the manuscript|designed all the experiments and analyzed the data|performed the mouse experiments	designed all the experiments and analyzed the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5126809	27894274	TA	2	conceived the study|wrote the manuscript|designed all the experiments and analyzed the data|performed the mouse experiments	performed the mouse experiments	Performed the experiments	Investigation	YES
5126809	27894274	TS	2	conceived the study|wrote the manuscript|designed all the experiments and analyzed the data|performed the human cell experiments	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5126809	27894274	TS	2	conceived the study|wrote the manuscript|designed all the experiments and analyzed the data|performed the human cell experiments	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5126809	27894274	TS	2	conceived the study|wrote the manuscript|designed all the experiments and analyzed the data|performed the human cell experiments	designed all the experiments and analyzed the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5126809	27894274	TS	2	conceived the study|wrote the manuscript|designed all the experiments and analyzed the data|performed the human cell experiments	performed the human cell experiments	Performed the experiments	Investigation	YES
5126809	27894274	TU	2	performed the mouse experiments	performed the mouse experiments	Performed the experiments	Investigation	YES
5126809	27894274	TY	2	supervised the project	supervised the project	-	Supervision	YES
5126809	27894274	YI	2	performed the mouse experiments	performed the mouse experiments	Performed the experiments	Investigation	YES
4484826	26137546	EE	2	was the sole contributor to this paper	was the sole contributor to this paper	-	-	NO
3522536	22793790	All authors	2	reviewed and approved the final manuscript	reviewed and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4401744	25885034	JS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401744	25885034	JS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401744	25885034	JS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401744	25885034	PW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401744	25885034	PW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401744	25885034	PW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401744	25885034	PW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5126826	27894252	EK	2	collected the samples and corrected the manuscript	collected the samples and corrected the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5126826	27894252	HW	2	conceived the experiments, participated in its design and corrected the manuscript	conceived the experiments, participated in its design and corrected the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
5126826	27894252	JL	2	collected the samples and corrected the manuscript	collected the samples and corrected the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5126826	27894252	LH	2	conducted the data analysis	conducted the data analysis	Analyzed the data	Formal analysis	YES
5126826	27894252	WZ	2	performed the experiments and wrote the manuscript|conducted the data analysis	performed the experiments and wrote the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5126826	27894252	WZ	2	performed the experiments and wrote the manuscript|conducted the data analysis	conducted the data analysis	Analyzed the data	Formal analysis	YES
5126826	27894252	YG	2	conducted the data analysis|collected the samples and corrected the manuscript	conducted the data analysis	Analyzed the data	Formal analysis	YES
5126826	27894252	YG	2	conducted the data analysis|collected the samples and corrected the manuscript	collected the samples and corrected the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
3526468	23181827	AM	2	were involved in the study design and collection of data	were involved in the study design and collection of data	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3526468	23181827	All authors	2	reviewed the draft of the manuscript before submission	reviewed the draft of the manuscript before submission	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3526468	23181827	JA	2	were involved in the study design and collection of data	were involved in the study design and collection of data	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3526468	23181827	JS	2	analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3526468	23181827	KM	2	were involved in the study design and collection of data	were involved in the study design and collection of data	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3526468	23181827	MI	2	were involved in the study design, collection of data, and writing of the manuscript	were involved in the study design, collection of data, and writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
3526468	23181827	PP	2	was involved in the study design and writing of the manuscript	was involved in the study design and writing of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3526468	23181827	SV	2	were involved in the study design and collection of data	were involved in the study design and collection of data	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3526468	23181827	TB	2	were involved in the study design, collection of data, and writing of the manuscript|analyzed the data and wrote the manuscript	were involved in the study design, collection of data, and writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
3526468	23181827	TB	2	were involved in the study design, collection of data, and writing of the manuscript|analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3526468	23181827	TI	2	collected the data and assisted in the writing of the manuscript	collected the data and assisted in the writing of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3526468	23181827	TN	2	was involved in the study design	was involved in the study design	Conceived and designed the experiments	Methodology	YES
3526468	23181827	TP	2	were involved in the study design and collection of data	were involved in the study design and collection of data	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3526468	23181827	WS	2	were involved in the study design, collection of data, and writing of the manuscript	were involved in the study design, collection of data, and writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
3526468	23181827	YI	2	were involved in the study design, collection of data, and writing of the manuscript	were involved in the study design, collection of data, and writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
3526564	23181440	BL	2	conceived of the study, participated in its design and draft the manuscript	conceived of the study, participated in its design and draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
3526564	23181440	GZ	2	conceived of the study, participated in its design and draft the manuscript	conceived of the study, participated in its design and draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
3526564	23181440	JS	2	participated in data collection	participated in data collection	Performed the experiments	Investigation	YES
3526564	23181440	LL	2	participated in data collection	participated in data collection	Performed the experiments	Investigation	YES
3526564	23181440	LZ	2	conceived of the study, participated in its design and draft the manuscript	conceived of the study, participated in its design and draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
4401745	25886074	EJB	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4401745	25886074	EJB	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401745	25886074	JC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401745	25886074	JC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401745	25886074	JC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401745	25886074	JC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401745	25886074	JC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401745	25886074	LC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4401745	25886074	LC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401745	25886074	MCH	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4401745	25886074	MCH	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401745	25886074	MCIO	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4401745	25886074	MCIO	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401745	25886074	MJGB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401745	25886074	MJGB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401745	25886074	MJGB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401745	25886074	MJGB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401745	25886074	MJGB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401745	25886074	SC	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4401745	25886074	SC	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401745	25886074	VSR	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4401745	25886074	VSR	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5489665	28706523	All of the authors	2	have read and approved the current manuscript	have read and approved the current manuscript	-	-	NO
4485482	26137540	AB	2	included and provided care to the patients	included and provided care to the patients	Performed the experiments	Investigation	YES
4485482	26137540	CA	2	included and provided care to the patients	included and provided care to the patients	Performed the experiments	Investigation	YES
4485482	26137540	CG	2	included and provided care to the patients	included and provided care to the patients	Performed the experiments	Investigation	YES
4485482	26137540	CL	2	performed the cytometry analysis	performed the cytometry analysis	Performed the experiments	Investigation	YES
4485482	26137540	CLVK	2	designed the study, wrote and edited the manuscript	designed the study, wrote and edited the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft|Writing - Review & Editing	YES
4485482	26137540	CP	2	performed the cytometry analysis	performed the cytometry analysis	Performed the experiments	Investigation	YES
4485482	26137540	JP	2	performed the cytometry analysis	performed the cytometry analysis	Performed the experiments	Investigation	YES
4485482	26137540	MHO	2	included and provided care to the patients	included and provided care to the patients	Performed the experiments	Investigation	YES
4485482	26137540	MdM	2	included and provided care to the patients	included and provided care to the patients	Performed the experiments	Investigation	YES
4485482	26137540	VB	2	is the principal investigator of the clinical study|designed the study, analysed data, wrote and edited the manuscript|included and provided care to the patients	is the principal investigator of the clinical study	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
4485482	26137540	VB	2	is the principal investigator of the clinical study|designed the study, analysed data, wrote and edited the manuscript|included and provided care to the patients	designed the study, analysed data, wrote and edited the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
4485482	26137540	VB	2	is the principal investigator of the clinical study|designed the study, analysed data, wrote and edited the manuscript|included and provided care to the patients	included and provided care to the patients	Performed the experiments	Investigation	YES
4485482	26137540	WEN	2	designed the study, analysed data, wrote and edited the manuscript	designed the study, analysed data, wrote and edited the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
4485482	26137540	YC	2	designed the study, wrote and edited the manuscript	designed the study, wrote and edited the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5126864	27894253	A.Q.	2	designed the experiment|collected the data|performed the bioinformatic analysis	designed the experiment	Conceived and designed the experiments	Methodology	YES
5126864	27894253	A.Q.	2	designed the experiment|collected the data|performed the bioinformatic analysis	collected the data	Performed the experiments	Investigation	YES
5126864	27894253	A.Q.	2	designed the experiment|collected the data|performed the bioinformatic analysis	performed the bioinformatic analysis	Performed the experiments	Formal analysis|Investigation	YES
5126864	27894253	F.M.J.	2	designed the experiment|analysed the data and wrote the paper	designed the experiment	Conceived and designed the experiments	Methodology	YES
5126864	27894253	F.M.J.	2	designed the experiment|analysed the data and wrote the paper	analysed the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5126864	27894253	P.J.	2	designed the experiment|performed the bioinformatic analysis|analysed the data and wrote the paper	designed the experiment	Conceived and designed the experiments	Methodology	YES
5126864	27894253	P.J.	2	designed the experiment|performed the bioinformatic analysis|analysed the data and wrote the paper	performed the bioinformatic analysis	Performed the experiments	Formal analysis|Investigation	YES
5126864	27894253	P.J.	2	designed the experiment|performed the bioinformatic analysis|analysed the data and wrote the paper	analysed the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3526567	23181417	All authors	2	agreed with the final manuscript to be submitted	agreed with the final manuscript to be submitted	Wrote the paper	Writing - Review & Editing	YES
3526567	23181417	BCNT	2	designed the study|collected and entered data|did data analysis and manuscript write-up	designed the study	Conceived and designed the experiments	Methodology	YES
3526567	23181417	BCNT	2	designed the study|collected and entered data|did data analysis and manuscript write-up	collected and entered data	Performed the experiments	Investigation	YES
3526567	23181417	BCNT	2	designed the study|collected and entered data|did data analysis and manuscript write-up	did data analysis and manuscript write-up	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3526567	23181417	ET	2	designed the study|did data analysis and manuscript write-up	designed the study	Conceived and designed the experiments	Methodology	YES
3526567	23181417	ET	2	designed the study|did data analysis and manuscript write-up	did data analysis and manuscript write-up	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3526567	23181417	HNL	2	designed the study|did data analysis and manuscript write-up	designed the study	Conceived and designed the experiments	Methodology	YES
3526567	23181417	HNL	2	designed the study|did data analysis and manuscript write-up	did data analysis and manuscript write-up	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3526567	23181417	MSD	2	designed the study|did manuscript proofreading and editing	designed the study	Conceived and designed the experiments	Methodology	YES
3526567	23181417	MSD	2	designed the study|did manuscript proofreading and editing	did manuscript proofreading and editing	Wrote the paper	Writing - Review & Editing	YES
3526567	23181417	VNKS	2	collected and entered data	collected and entered data	Performed the experiments	Investigation	YES
3526567	23181417	VPD	2	designed the study|did manuscript proofreading and editing	designed the study	Conceived and designed the experiments	Methodology	YES
3526567	23181417	VPD	2	designed the study|did manuscript proofreading and editing	did manuscript proofreading and editing	Wrote the paper	Writing - Review & Editing	YES
3526567	23181417	YNM	2	collected and entered data	collected and entered data	Performed the experiments	Investigation	YES
4401746	25886567	AFRP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401746	25886567	AFRP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401746	25886567	AFRP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401746	25886567	AFRP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401746	25886567	AHM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401746	25886567	AZS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4401746	25886567	AZS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401746	25886567	DERA	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4401746	25886567	DERA	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401746	25886567	KMM	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4401746	25886567	KMM	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401746	25886567	LAC	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401746	25886567	LAC	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401746	25886567	LYK	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4401746	25886567	LYK	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401746	25886567	MJE	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401746	25886567	MJE	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401746	25886567	MJE	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401746	25886567	SNS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401746	25886567	SNS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4450277	26090425	Feng Chen	2	contributed equally to the paper	contributed equally to the paper	-	-	NO
4450277	26090425	Tingting Ai	2	contributed equally to the paper	contributed equally to the paper	-	-	NO
3527298	22838398	EM	2	provided scientific guidance	provided scientific guidance	-	Supervision	YES
3527298	22838398	ES	2	conceived the experiment|performed bioinformatics and data analysis	conceived the experiment	Conceived and designed the experiments	Conceptualization	YES
3527298	22838398	ES	2	conceived the experiment|performed bioinformatics and data analysis	performed bioinformatics and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3527298	22838398	JK	2	performed bioinformatics and data analysis	performed bioinformatics and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3527298	22838398	MK	2	performed bioinformatics and data analysis	performed bioinformatics and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3527298	22838398	PK	2	provided scientific guidance	provided scientific guidance	-	Supervision	YES
3527298	22838398	PM	2	helped with patient recruitment and clinical follow-up	helped with patient recruitment and clinical follow-up	Performed the experiments	Investigation	YES
3527298	22838398	RL	2	performed bioinformatics and data analysis	performed bioinformatics and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3527298	22838398	VW	2	conceived the experiment|performed bioinformatics and data analysis	conceived the experiment	Conceived and designed the experiments	Conceptualization	YES
3527298	22838398	VW	2	conceived the experiment|performed bioinformatics and data analysis	performed bioinformatics and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5489684	28706528	All Authors	2	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5489684	28706528	ED	2	performed the heat-stress experiment, samples processing and lab work	performed the heat-stress experiment, samples processing and lab work	Performed the experiments	Data curation|Investigation	YES
5489684	28706528	GP	2	planned and designed the study	planned and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5489684	28706528	JR	2	planned and designed the study	planned and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5489684	28706528	LE	2	conducted bioinformatics and data analysis	conducted bioinformatics and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5489684	28706528	LM	2	planned and designed the study|performed the heat-stress experiment, samples processing and lab work|led the writing of the paper with contributions from the rest of authors	planned and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5489684	28706528	LM	2	planned and designed the study|performed the heat-stress experiment, samples processing and lab work|led the writing of the paper with contributions from the rest of authors	performed the heat-stress experiment, samples processing and lab work	Performed the experiments	Data curation|Investigation	YES
5489684	28706528	LM	2	planned and designed the study|performed the heat-stress experiment, samples processing and lab work|led the writing of the paper with contributions from the rest of authors	led the writing of the paper with contributions from the rest of authors	Wrote the paper	Writing - Original Draft	YES
5464344	28603634	Alison M. Bendele	1	Conducted Experiments|Analysis	Conducted Experiments	Performed the experiments	Investigation	YES
5464344	28603634	Alison M. Bendele	1	Conducted Experiments|Analysis	Analysis	-	-	NO
5464344	28603634	Anita K. Harvey	1	Conducted Experiments|Analysis	Conducted Experiments	Performed the experiments	Investigation	YES
5464344	28603634	Anita K. Harvey	1	Conducted Experiments|Analysis	Analysis	-	-	NO
5464344	28603634	Chaohua Lin	1	Conducted Experiments	Conducted Experiments	Performed the experiments	Investigation	YES
5464344	28603634	Jennifer L. Oskins	1	Conducted Experiments	Conducted Experiments	Performed the experiments	Investigation	YES
5464344	28603634	Mark G. Chambers	1	Analysis	Analysis	-	-	NO
5464344	28603634	Srinivasan Chandrasekhar	1	Analysis	Analysis	-	-	NO
5464344	28603634	Xiao-Peng Yu	1	Conducted Experiments|Analysis	Conducted Experiments	Performed the experiments	Investigation	YES
5464344	28603634	Xiao-Peng Yu	1	Conducted Experiments|Analysis	Analysis	-	-	NO
5464344	28603634	Xushan Wang	1	Conducted Experiments|Analysis	Conducted Experiments	Performed the experiments	Investigation	YES
5464344	28603634	Xushan Wang	1	Conducted Experiments|Analysis	Analysis	-	-	NO
4401748	25885273	APL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401748	25885273	APL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401748	25885273	APL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401748	25885273	APL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401748	25885273	APL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401748	25885273	AWS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401748	25885273	AWS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401748	25885273	AWS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401748	25885273	AWS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401748	25885273	AWS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401748	25885273	MRD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401748	25885273	MRD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401748	25885273	MRD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401748	25885273	MRD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401748	25885273	MRD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401748	25885273	PRR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401748	25885273	PRR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401748	25885273	PRR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401748	25885273	PRR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401748	25885273	PRR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401748	25885273	SV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401748	25885273	SV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401748	25885273	SV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401748	25885273	SV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401748	25885273	SV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5127058	27894259	AMD	PLoS52	analyzed the data|authors reviewed and approved the final manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5127058	27894259	AMD	PLoS52	analyzed the data|authors reviewed and approved the final manuscript	authors reviewed and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5127058	27894259	All	PLoS52	authors reviewed and approved the final manuscript	authors reviewed and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5127058	27894259	BJW	PLoS52	conceived and designed the project|participated in data acquisition	conceived and designed the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5127058	27894259	BJW	PLoS52	conceived and designed the project|participated in data acquisition	participated in data acquisition	Performed the experiments	Investigation	YES
5127058	27894259	BVL	PLoS52	conceived and designed the project|participated in data acquisition|authors reviewed and approved the final manuscript	conceived and designed the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5127058	27894259	BVL	PLoS52	conceived and designed the project|participated in data acquisition|authors reviewed and approved the final manuscript	participated in data acquisition	Performed the experiments	Investigation	YES
5127058	27894259	BVL	PLoS52	conceived and designed the project|participated in data acquisition|authors reviewed and approved the final manuscript	authors reviewed and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5127058	27894259	CGC-M	PLoS52	conceived and designed the project|authors reviewed and approved the final manuscript	conceived and designed the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5127058	27894259	CGC-M	PLoS52	conceived and designed the project|authors reviewed and approved the final manuscript	authors reviewed and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5127058	27894259	DMB-H	PLoS52	conceived and designed the project|participated in data acquisition|authors reviewed and approved the final manuscript	conceived and designed the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5127058	27894259	DMB-H	PLoS52	conceived and designed the project|participated in data acquisition|authors reviewed and approved the final manuscript	participated in data acquisition	Performed the experiments	Investigation	YES
5127058	27894259	DMB-H	PLoS52	conceived and designed the project|participated in data acquisition|authors reviewed and approved the final manuscript	authors reviewed and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5127058	27894259	GPH	PLoS52	conceived and designed the project|participated in data acquisition|authors reviewed and approved the final manuscript	conceived and designed the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5127058	27894259	GPH	PLoS52	conceived and designed the project|participated in data acquisition|authors reviewed and approved the final manuscript	participated in data acquisition	Performed the experiments	Investigation	YES
5127058	27894259	GPH	PLoS52	conceived and designed the project|participated in data acquisition|authors reviewed and approved the final manuscript	authors reviewed and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5127058	27894259	GS	PLoS52	participated in data acquisition|analyzed the data	participated in data acquisition	Performed the experiments	Investigation	YES
5127058	27894259	GS	PLoS52	participated in data acquisition|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5127058	27894259	JLB	PLoS52	participated in data acquisition	participated in data acquisition	Performed the experiments	Investigation	YES
5127058	27894259	KDD	PLoS52	conceived and designed the project|participated in data acquisition|authors reviewed and approved the final manuscript	conceived and designed the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5127058	27894259	KDD	PLoS52	conceived and designed the project|participated in data acquisition|authors reviewed and approved the final manuscript	participated in data acquisition	Performed the experiments	Investigation	YES
5127058	27894259	KDD	PLoS52	conceived and designed the project|participated in data acquisition|authors reviewed and approved the final manuscript	authors reviewed and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5127058	27894259	MDA	PLoS52	conceived and designed the project|participated in data acquisition	conceived and designed the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5127058	27894259	MDA	PLoS52	conceived and designed the project|participated in data acquisition	participated in data acquisition	Performed the experiments	Investigation	YES
5127058	27894259	MLC	PLoS52	conceived and designed the project|participated in data acquisition|analyzed the data	conceived and designed the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5127058	27894259	MLC	PLoS52	conceived and designed the project|participated in data acquisition|analyzed the data	participated in data acquisition	Performed the experiments	Investigation	YES
5127058	27894259	MLC	PLoS52	conceived and designed the project|participated in data acquisition|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5127058	27894259	MPH	PLoS52	conceived and designed the project|authors reviewed and approved the final manuscript	conceived and designed the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5127058	27894259	MPH	PLoS52	conceived and designed the project|authors reviewed and approved the final manuscript	authors reviewed and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5127058	27894259	MTS	PLoS52	participated in data acquisition|authors reviewed and approved the final manuscript	participated in data acquisition	Performed the experiments	Investigation	YES
5127058	27894259	MTS	PLoS52	participated in data acquisition|authors reviewed and approved the final manuscript	authors reviewed and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5127058	27894259	RLL	PLoS52	conceived and designed the project|participated in data acquisition|authors reviewed and approved the final manuscript	conceived and designed the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5127058	27894259	RLL	PLoS52	conceived and designed the project|participated in data acquisition|authors reviewed and approved the final manuscript	participated in data acquisition	Performed the experiments	Investigation	YES
5127058	27894259	RLL	PLoS52	conceived and designed the project|participated in data acquisition|authors reviewed and approved the final manuscript	authors reviewed and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5127058	27894259	RWM	PLoS52	conceived and designed the project|participated in data acquisition|authors reviewed and approved the final manuscript	conceived and designed the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5127058	27894259	RWM	PLoS52	conceived and designed the project|participated in data acquisition|authors reviewed and approved the final manuscript	participated in data acquisition	Performed the experiments	Investigation	YES
5127058	27894259	RWM	PLoS52	conceived and designed the project|participated in data acquisition|authors reviewed and approved the final manuscript	authors reviewed and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5127058	27894259	SFC	PLoS52	conceived and designed the project|participated in data acquisition|authors reviewed and approved the final manuscript	conceived and designed the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5127058	27894259	SFC	PLoS52	conceived and designed the project|participated in data acquisition|authors reviewed and approved the final manuscript	participated in data acquisition	Performed the experiments	Investigation	YES
5127058	27894259	SFC	PLoS52	conceived and designed the project|participated in data acquisition|authors reviewed and approved the final manuscript	authors reviewed and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5127058	27894259	TPLS	PLoS52	conceived and designed the project|participated in data acquisition|authors reviewed and approved the final manuscript	conceived and designed the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5127058	27894259	TPLS	PLoS52	conceived and designed the project|participated in data acquisition|authors reviewed and approved the final manuscript	participated in data acquisition	Performed the experiments	Investigation	YES
5127058	27894259	TPLS	PLoS52	conceived and designed the project|participated in data acquisition|authors reviewed and approved the final manuscript	authors reviewed and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5127058	27894259	TSK	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
3533776	23098156	GM	2	conceived of the study, participated in study design, data interpretation and critically revised the manuscript	conceived of the study, participated in study design, data interpretation and critically revised the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Review & Editing	YES
3533776	23098156	HMM	2	participated in the study design, data interpretation, and critically revised the manuscript	participated in the study design, data interpretation, and critically revised the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
3533776	23098156	JAD	2	participated in the study design, acquisition of data, and critically revised the manuscript	participated in the study design, acquisition of data, and critically revised the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
3533776	23098156	NSL	2	participated in study design and critically revised the manuscript	participated in study design and critically revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
3533776	23098156	PJS	2	performed the analysis of the samples and helped to draft the manuscript	performed the analysis of the samples and helped to draft the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3533776	23098156	PZS	2	participated in the study design, acquisition of data, data analysis and interpretation and drafted the manuscript	participated in the study design, acquisition of data, data analysis and interpretation and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4485486	26137533	A.O.	2	coordinated inclusion of patients and collected clinical data	coordinated inclusion of patients and collected clinical data	Performed the experiments	Investigation|Project administration	YES
4485486	26137533	A.P.	2	coordinated inclusion of patients and collected clinical data	coordinated inclusion of patients and collected clinical data	Performed the experiments	Investigation|Project administration	YES
4485486	26137533	B.A.P.	2	performed research	performed research	Performed the experiments	Investigation	YES
4485486	26137533	C.A.R.	2	coordinated inclusion of patients and collected clinical data	coordinated inclusion of patients and collected clinical data	Performed the experiments	Investigation|Project administration	YES
4485486	26137533	C.W.H.	2	provided guidance on entropy comparisons and performed statistical analyses|discussed results	provided guidance on entropy comparisons and performed statistical analyses	Analyzed the data	Formal analysis|Supervision	YES
4485486	26137533	C.W.H.	2	provided guidance on entropy comparisons and performed statistical analyses|discussed results	discussed results	-	-	NO
4485486	26137533	D.A.F.	2	provided guidance on entropy comparisons and performed statistical analyses	provided guidance on entropy comparisons and performed statistical analyses	Analyzed the data	Formal analysis|Supervision	YES
4485486	26137533	D.M.	2	performed research|analyzed and interpreted data|designed the research|wrote the manuscript	performed research	Performed the experiments	Investigation	YES
4485486	26137533	D.M.	2	performed research|analyzed and interpreted data|designed the research|wrote the manuscript	analyzed and interpreted data	Analyzed the data	Formal analysis	YES
4485486	26137533	D.M.	2	performed research|analyzed and interpreted data|designed the research|wrote the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
4485486	26137533	D.M.	2	performed research|analyzed and interpreted data|designed the research|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4485486	26137533	E.G.	2	performed research	performed research	Performed the experiments	Investigation	YES
4485486	26137533	E.P.K.	2	performed research	performed research	Performed the experiments	Investigation	YES
4485486	26137533	H.I.	2	performed research|analyzed and interpreted data|performed virus sequencing	performed research	Performed the experiments	Investigation	YES
4485486	26137533	H.I.	2	performed research|analyzed and interpreted data|performed virus sequencing	analyzed and interpreted data	Analyzed the data	Formal analysis	YES
4485486	26137533	H.I.	2	performed research|analyzed and interpreted data|performed virus sequencing	performed virus sequencing	Performed the experiments	Investigation	YES
4485486	26137533	K.M.M.	2	performed research|analyzed and interpreted data	performed research	Performed the experiments	Investigation	YES
4485486	26137533	K.M.M.	2	performed research|analyzed and interpreted data	analyzed and interpreted data	Analyzed the data	Formal analysis	YES
4485486	26137533	K.O.P.	2	performed research	performed research	Performed the experiments	Investigation	YES
4485486	26137533	M.C.	2	discussed results|designed the research|wrote the manuscript	discussed results	-	-	NO
4485486	26137533	M.C.	2	discussed results|designed the research|wrote the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
4485486	26137533	M.C.	2	discussed results|designed the research|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4485486	26137533	M.G.Z.	2	performed research|analyzed and interpreted data	performed research	Performed the experiments	Investigation	YES
4485486	26137533	M.G.Z.	2	performed research|analyzed and interpreted data	analyzed and interpreted data	Analyzed the data	Formal analysis	YES
4485486	26137533	S.A.J.	2	performed research	performed research	Performed the experiments	Investigation	YES
4485486	26137533	S.A.M.	2	performed research|analyzed and interpreted data|coordinated inclusion of patients and collected clinical data|discussed results|designed the research|wrote the manuscript	performed research	Performed the experiments	Investigation	YES
4485486	26137533	S.A.M.	2	performed research|analyzed and interpreted data|coordinated inclusion of patients and collected clinical data|discussed results|designed the research|wrote the manuscript	analyzed and interpreted data	Analyzed the data	Formal analysis	YES
4485486	26137533	S.A.M.	2	performed research|analyzed and interpreted data|coordinated inclusion of patients and collected clinical data|discussed results|designed the research|wrote the manuscript	coordinated inclusion of patients and collected clinical data	Performed the experiments	Investigation|Project administration	YES
4485486	26137533	S.A.M.	2	performed research|analyzed and interpreted data|coordinated inclusion of patients and collected clinical data|discussed results|designed the research|wrote the manuscript	discussed results	-	-	NO
4485486	26137533	S.A.M.	2	performed research|analyzed and interpreted data|coordinated inclusion of patients and collected clinical data|discussed results|designed the research|wrote the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
4485486	26137533	S.A.M.	2	performed research|analyzed and interpreted data|coordinated inclusion of patients and collected clinical data|discussed results|designed the research|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4485486	26137533	S.A.T.	2	performed research	performed research	Performed the experiments	Investigation	YES
4485486	26137533	S.J.	2	coordinated inclusion of patients and collected clinical data	coordinated inclusion of patients and collected clinical data	Performed the experiments	Investigation|Project administration	YES
5464345	28603635	All authors	2	were involved in the design of the study and all authors contributed to the intellectual content of the manuscript	were involved in the design of the study and all authors contributed to the intellectual content of the manuscript	Conceived and designed the experiments	Methodology	YES
5464345	28603635	MH	2	contributed to the critical revision of the data and results, and revised the manuscript	contributed to the critical revision of the data and results, and revised the manuscript	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Review & Editing	YES
5464345	28603635	SF	2	contributed to the critical revision of the data and results, and revised the manuscript	contributed to the critical revision of the data and results, and revised the manuscript	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Review & Editing	YES
5464345	28603635	TD	2	collected the data and developed the first draft of the manuscript|is the guarantor	collected the data and developed the first draft of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5464345	28603635	TD	2	collected the data and developed the first draft of the manuscript|is the guarantor	is the guarantor	-	-	NO
5464345	28603635	UL	2	contributed to the critical revision of the data and results, and revised the manuscript	contributed to the critical revision of the data and results, and revised the manuscript	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Review & Editing	YES
3537690	23253095	DY	2	provided intellectual content and revised several versions of the manuscript	provided intellectual content and revised several versions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
3537690	23253095	LD	2	provided intellectual content and revised several versions of the manuscript	provided intellectual content and revised several versions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
3537690	23253095	LM	2	conceived of the study|performed the searches and extracted the data|provided intellectual content and revised several versions of the manuscript	conceived of the study	Conceived and designed the experiments	Conceptualization	YES
3537690	23253095	LM	2	conceived of the study|performed the searches and extracted the data|provided intellectual content and revised several versions of the manuscript	performed the searches and extracted the data	Performed the experiments	Investigation	YES
3537690	23253095	LM	2	conceived of the study|performed the searches and extracted the data|provided intellectual content and revised several versions of the manuscript	provided intellectual content and revised several versions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
3537690	23253095	LT	2	conceived of the study|provided intellectual content and revised several versions of the manuscript	conceived of the study	Conceived and designed the experiments	Conceptualization	YES
3537690	23253095	LT	2	conceived of the study|provided intellectual content and revised several versions of the manuscript	provided intellectual content and revised several versions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
3537690	23253095	MS	2	provided intellectual content and revised several versions of the manuscript	provided intellectual content and revised several versions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
3537690	23253095	POZ	2	provided intellectual content and revised several versions of the manuscript	provided intellectual content and revised several versions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
3537690	23253095	SN	2	performed the searches and extracted the data|provided intellectual content and revised several versions of the manuscript	performed the searches and extracted the data	Performed the experiments	Investigation	YES
3537690	23253095	SN	2	performed the searches and extracted the data|provided intellectual content and revised several versions of the manuscript	provided intellectual content and revised several versions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4401749	25884951	HZ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401749	25884951	HZ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401749	25884951	HZ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401749	25884951	HZ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401749	25884951	JW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401749	25884951	JW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401749	25884951	JW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401749	25884951	LJ	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401749	25884951	LJ	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401749	25884951	LJ	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401749	25884951	NQ	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401749	25884951	NQ	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401749	25884951	NQ	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401749	25884951	WY	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401749	25884951	WY	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401749	25884951	WY	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401749	25884951	WY	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401749	25884951	XC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401749	25884951	XC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401749	25884951	XC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5489691	28706525	GA	2	involved part of the experiment and helped in revising the manuscript	involved part of the experiment and helped in revising the manuscript	Wrote the paper	Writing - Review & Editing	YES
5489691	28706525	JR	2	conceived and designed the experiment|involved in the development of cms lines	conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5489691	28706525	JR	2	conceived and designed the experiment|involved in the development of cms lines	involved in the development of cms lines	-	-	NO
5489691	28706525	PS	2	has performed the experiments	has performed the experiments	Performed the experiments	Investigation	YES
5489691	28706525	RC	2	prepared and approved the final version of the manuscript	prepared and approved the final version of the manuscript	Wrote the paper	Writing - Original Draft	YES
5489691	28706525	RS	2	involved in the development of cms lines	involved in the development of cms lines	-	-	NO
5489691	28706525	all authors	2	prepared and approved the final version of the manuscript	prepared and approved the final version of the manuscript	Wrote the paper	Writing - Original Draft	YES
5131402	27905879	BH	PLoS52	designed the study|jointly wrote and revised the paper	designed the study	Conceived and designed the experiments	Methodology	YES
5131402	27905879	BH	PLoS52	designed the study|jointly wrote and revised the paper	jointly wrote and revised the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5131402	27905879	MW	PLoS52	designed the study|collected samples|jointly wrote and revised the paper	designed the study	Conceived and designed the experiments	Methodology	YES
5131402	27905879	MW	PLoS52	designed the study|collected samples|jointly wrote and revised the paper	collected samples	Performed the experiments	Investigation	YES
5131402	27905879	MW	PLoS52	designed the study|collected samples|jointly wrote and revised the paper	jointly wrote and revised the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5131402	27905879	PC	PLoS52	analysed the data|jointly wrote and revised the paper	analysed the data	Analyzed the data	Formal analysis	YES
5131402	27905879	PC	PLoS52	analysed the data|jointly wrote and revised the paper	jointly wrote and revised the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3537734	23259683	All authors	2	read, gave input and approved the final manuscript	read, gave input and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
3537734	23259683	HVT	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
3537734	23259683	JA	2	designed the study|drafted the protocol and the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
3537734	23259683	JA	2	designed the study|drafted the protocol and the manuscript	drafted the protocol and the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3537734	23259683	MES	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
3537734	23259683	NEJ	2	performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
3537734	23259683	PP	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
4485489	26137562	J.L.D.	PLoS52	conceived and designed the study|analyzed the data and wrote the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4485489	26137562	J.L.D.	PLoS52	conceived and designed the study|analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4485489	26137562	S.K.L.	PLoS52	performed the experiments|conceived and designed the study	performed the experiments	Performed the experiments	Investigation	YES
4485489	26137562	S.K.L.	PLoS52	performed the experiments|conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4485489	26137562	S.Y.G.	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
4485489	26137562	Y.G.	PLoS52	analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4485489	26137562	Y.Q.W.	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
4401750	25885532	AM	PLoS5	Wrote the paper|Reviewed for critical content and approved final revision	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401750	25885532	AM	PLoS5	Wrote the paper|Reviewed for critical content and approved final revision	Reviewed for critical content and approved final revision	Wrote the paper	Writing - Review & Editing	YES
4401750	25885532	BN	PLoS5	Wrote the paper|Reviewed for critical content and approved final revision	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401750	25885532	BN	PLoS5	Wrote the paper|Reviewed for critical content and approved final revision	Reviewed for critical content and approved final revision	Wrote the paper	Writing - Review & Editing	YES
4401750	25885532	CO	PLoS5	Wrote the paper|Reviewed for critical content and approved final revision	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401750	25885532	CO	PLoS5	Wrote the paper|Reviewed for critical content and approved final revision	Reviewed for critical content and approved final revision	Wrote the paper	Writing - Review & Editing	YES
4401750	25885532	HC	PLoS5	Wrote the paper|Reviewed for critical content and approved final revision	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401750	25885532	HC	PLoS5	Wrote the paper|Reviewed for critical content and approved final revision	Reviewed for critical content and approved final revision	Wrote the paper	Writing - Review & Editing	YES
4401750	25885532	HTB	PLoS5	Wrote the paper|Reviewed for critical content and approved final revision	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401750	25885532	HTB	PLoS5	Wrote the paper|Reviewed for critical content and approved final revision	Reviewed for critical content and approved final revision	Wrote the paper	Writing - Review & Editing	YES
4401750	25885532	IS	PLoS5	Analyzed the data|Wrote the paper|Reviewed for critical content and approved final revision	Analyzed the data	Analyzed the data	Formal analysis	YES
4401750	25885532	IS	PLoS5	Analyzed the data|Wrote the paper|Reviewed for critical content and approved final revision	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401750	25885532	IS	PLoS5	Analyzed the data|Wrote the paper|Reviewed for critical content and approved final revision	Reviewed for critical content and approved final revision	Wrote the paper	Writing - Review & Editing	YES
4401750	25885532	NC	PLoS5	Wrote the paper|Reviewed for critical content and approved final revision	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401750	25885532	NC	PLoS5	Wrote the paper|Reviewed for critical content and approved final revision	Reviewed for critical content and approved final revision	Wrote the paper	Writing - Review & Editing	YES
4401750	25885532	PN	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Reviewed for critical content and approved final revision	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401750	25885532	PN	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Reviewed for critical content and approved final revision	Analyzed the data	Analyzed the data	Formal analysis	YES
4401750	25885532	PN	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Reviewed for critical content and approved final revision	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401750	25885532	PN	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Reviewed for critical content and approved final revision	Reviewed for critical content and approved final revision	Wrote the paper	Writing - Review & Editing	YES
4401750	25885532	RB	PLoS5	Wrote the paper|Reviewed for critical content and approved final revision	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401750	25885532	RB	PLoS5	Wrote the paper|Reviewed for critical content and approved final revision	Reviewed for critical content and approved final revision	Wrote the paper	Writing - Review & Editing	YES
4401750	25885532	RC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Reviewed for critical content and approved final revision	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401750	25885532	RC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Reviewed for critical content and approved final revision	Analyzed the data	Analyzed the data	Formal analysis	YES
4401750	25885532	RC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Reviewed for critical content and approved final revision	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401750	25885532	RC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Reviewed for critical content and approved final revision	Reviewed for critical content and approved final revision	Wrote the paper	Writing - Review & Editing	YES
4401750	25885532	SS	PLoS5	Wrote the paper|Reviewed for critical content and approved final revision	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401750	25885532	SS	PLoS5	Wrote the paper|Reviewed for critical content and approved final revision	Reviewed for critical content and approved final revision	Wrote the paper	Writing - Review & Editing	YES
4401750	25885532	TC	PLoS5	Wrote the paper|Reviewed for critical content and approved final revision	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401750	25885532	TC	PLoS5	Wrote the paper|Reviewed for critical content and approved final revision	Reviewed for critical content and approved final revision	Wrote the paper	Writing - Review & Editing	YES
4450280	26120583	Peifu Tang	2	have contributed equally to this work	have contributed equally to this work	-	-	NO
4450280	26120583	Qi Xiong	2	have contributed equally to this work	have contributed equally to this work	-	-	NO
3540004	23126233	ACLP	2	participated in study design and data acquisition	participated in study design and data acquisition	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3540004	23126233	BA	2	participated in manuscript writing	participated in manuscript writing	Wrote the paper	Writing - Original Draft	YES
3540004	23126233	LKL	2	participated in manuscript writing	participated in manuscript writing	Wrote the paper	Writing - Original Draft	YES
3540004	23126233	WCS	2	participated in manuscript writing	participated in manuscript writing	Wrote the paper	Writing - Original Draft	YES
3540004	23126233	WMK	2	performed data acquisition, data analysis and manuscript writing	performed data acquisition, data analysis and manuscript writing	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3540004	23126233	YSL	2	participated in manuscript writing	participated in manuscript writing	Wrote the paper	Writing - Original Draft	YES
5489703	28706532	The author	2	confirms being the sole contributor of this work and approved it for publication	confirms being the sole contributor of this work and approved it for publication	-	-	NO
2905774	20648223	Alkis Saridis	2	performed many operations, collected data and revised manuscript	performed many operations, collected data and revised manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
2905774	20648223	Charalambos Matzaroglou	2	performed many operations, collected data and drafted manuscript	performed many operations, collected data and drafted manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
2905774	20648223	Element Analysis	2	revised manuscript	revised manuscript	Wrote the paper	Writing - Review & Editing	YES
2905774	20648223	Elias Panagiotopoulos	2	supervised most operations, directed patient care and revised manuscript	supervised most operations, directed patient care and revised manuscript	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Review & Editing	YES
2905774	20648223	Menelaos Karanikolas	2	provided anesthesia for many procedures, organized, revised and submitted manuscript	provided anesthesia for many procedures, organized, revised and submitted manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
2905774	20648223	Panagiotis Bougas	2	assisted with most operations and collected data	assisted with most operations and collected data	Performed the experiments	Investigation	YES
5131501	27903243	CAW	2	performed the data analysis|wrote and edited the manuscript, and approved the final manuscript	performed the data analysis	Analyzed the data	Formal analysis	YES
5131501	27903243	CAW	2	performed the data analysis|wrote and edited the manuscript, and approved the final manuscript	wrote and edited the manuscript, and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5131501	27903243	TI	2	conceived the project idea and wrote necessary programs|performed the data analysis|wrote and edited the manuscript, and approved the final manuscript	conceived the project idea and wrote necessary programs	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Software|Writing - Original Draft	YES
5131501	27903243	TI	2	conceived the project idea and wrote necessary programs|performed the data analysis|wrote and edited the manuscript, and approved the final manuscript	performed the data analysis	Analyzed the data	Formal analysis	YES
5131501	27903243	TI	2	conceived the project idea and wrote necessary programs|performed the data analysis|wrote and edited the manuscript, and approved the final manuscript	wrote and edited the manuscript, and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4401751	25886041	ASW	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401751	25886041	DY	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401751	25886041	ML	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401751	25886041	SLY	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401751	25886041	XNZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401751	25886041	YL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401751	25886041	YL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401751	25886041	YL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401751	25886041	YY	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401751	25886041	ZGX	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4450281	26090457	Alejandro Saavedra Tascon	2	participated in data collection and interpretation of the findings	participated in data collection and interpretation of the findings	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4450281	26090457	Jose L. Hernandez	2	was responsible of performing diagnostic and follow up ultrasound	was responsible of performing diagnostic and follow up ultrasound	Performed the experiments	Investigation	YES
4450281	26090457	Julio Urresta Avila	2	participated in data collection and interpretation of the findings	participated in data collection and interpretation of the findings	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4450281	26090457	Maite Lopez-Yarto	2	participated in surgery of the myomas, paper writing, and revision	participated in surgery of the myomas, paper writing, and revision	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4450281	26090457	Ramon Carreras Collado	2	helped with paper writing and revision	helped with paper writing and revision	Wrote the paper	Writing - Review & Editing	YES
4450281	26090457	Sergio Haimovich	2	was responsible of the conception and design of the study, surgery of the myomas, supervision of data collection, data analysis, and interpretation of the findings of the study, as well as paper writing and revision	was responsible of the conception and design of the study, surgery of the myomas, supervision of data collection, data analysis, and interpretation of the findings of the study, as well as paper writing and revision	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Supervision|Writing - Review & Editing	YES
3544704	23020962	AC	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
3544704	23020962	AM	2	have contributed to study design, analysis and interpretation of data	have contributed to study design, analysis and interpretation of data	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Methodology|Resources	YES
3544704	23020962	HG	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
3544704	23020962	LL	2	have contributed to study design, analysis and interpretation of data	have contributed to study design, analysis and interpretation of data	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Methodology|Resources	YES
3544704	23020962	MV	2	has performed statistical analysis	has performed statistical analysis	Analyzed the data	Formal analysis	YES
3544704	23020962	NB	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
3544704	23020962	NV	2	has contributed to interpretation of data and has revised critically the manuscript	has contributed to interpretation of data and has revised critically the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
3544704	23020962	OL	2	have participated in data interpretation and manuscript drafting	have participated in data interpretation and manuscript drafting	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3544704	23020962	YY	2	have participated in data interpretation and manuscript drafting	have participated in data interpretation and manuscript drafting	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4485902	26137572	AC	PLoS52	performed confocal analysis	performed confocal analysis	Performed the experiments	Investigation	YES
4485902	26137572	AD	PLoS52	performed experiments on human samples	performed experiments on human samples	Performed the experiments	Investigation	YES
4485902	26137572	AM	PLoS52	designed the study, organized the experiments|wrote the paper	designed the study, organized the experiments	Conceived and designed the experiments	Methodology|Project administration	YES
4485902	26137572	AM	PLoS52	designed the study, organized the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4485902	26137572	All authors	PLoS52	contributed to acquisition, analysis and interpretation of data	contributed to acquisition, analysis and interpretation of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
4485902	26137572	CN	PLoS52	performed histological analysis and managed the mouse models	performed histological analysis and managed the mouse models	Performed the experiments	Investigation|Methodology	YES
4485902	26137572	EB	PLoS52	collected human biopsies and samples	collected human biopsies and samples	Performed the experiments	Investigation	YES
4485902	26137572	FB	PLoS52	designed the study, organized the experiments	designed the study, organized the experiments	Conceived and designed the experiments	Methodology|Project administration	YES
4485902	26137572	FC	PLoS52	performed histological analysis and managed the mouse models	performed histological analysis and managed the mouse models	Performed the experiments	Investigation|Methodology	YES
4485902	26137572	GM	PLoS52	performed treadmill functional analysis and cell culture experiments	performed treadmill functional analysis and cell culture experiments	Performed the experiments	Investigation	YES
4485902	26137572	LDP	PLoS52	performed experiments on human samples	performed experiments on human samples	Performed the experiments	Investigation	YES
4485902	26137572	LP	PLoS52	performed molecular and statistic analysis	performed molecular and statistic analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4485902	26137572	MGB	PLoS52	performed molecular and statistic analysis	performed molecular and statistic analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5131533	27905883	AND	2	made the genome survey, the correlations studies and prepared the manuscript	made the genome survey, the correlations studies and prepared the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5131533	27905883	HCS	2	made the genome survey, the correlations studies and prepared the manuscript	made the genome survey, the correlations studies and prepared the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5131533	27905883	MDL	2	designed experiments|made the genome survey, the correlations studies and prepared the manuscript	designed experiments	Conceived and designed the experiments	Methodology	YES
5131533	27905883	MDL	2	designed experiments|made the genome survey, the correlations studies and prepared the manuscript	made the genome survey, the correlations studies and prepared the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5489704	28706531	AAB	2	conceived the idea of the review and prepared the initial outline and wrote the first draft|had major and equal contribution in overall preparation of manuscript	conceived the idea of the review and prepared the initial outline and wrote the first draft	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5489704	28706531	AAB	2	conceived the idea of the review and prepared the initial outline and wrote the first draft|had major and equal contribution in overall preparation of manuscript	had major and equal contribution in overall preparation of manuscript	Wrote the paper	Writing - Original Draft	YES
5489704	28706531	AF	2	gathered the literature and contributed in writing the different sections	gathered the literature and contributed in writing the different sections	Wrote the paper	Writing - Original Draft	YES
5489704	28706531	AZ	2	gathered the literature and contributed in writing the different sections	gathered the literature and contributed in writing the different sections	Wrote the paper	Writing - Original Draft	YES
5489704	28706531	CW	2	gathered the literature and contributed in writing the different sections	gathered the literature and contributed in writing the different sections	Wrote the paper	Writing - Original Draft	YES
5489704	28706531	DW	2	gathered the literature and contributed in writing the different sections	gathered the literature and contributed in writing the different sections	Wrote the paper	Writing - Original Draft	YES
5489704	28706531	HA	2	gathered the literature and contributed in writing the different sections	gathered the literature and contributed in writing the different sections	Wrote the paper	Writing - Original Draft	YES
5489704	28706531	JH	2	provided the technical guidance and editing support	provided the technical guidance and editing support	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Review & Editing	YES
5489704	28706531	MI	2	gathered the literature and contributed in writing the different sections	gathered the literature and contributed in writing the different sections	Wrote the paper	Writing - Original Draft	YES
5489704	28706531	SA	2	gathered the literature and contributed in writing the different sections|provided the technical guidance and editing support	gathered the literature and contributed in writing the different sections	Wrote the paper	Writing - Original Draft	YES
5489704	28706531	SA	2	gathered the literature and contributed in writing the different sections|provided the technical guidance and editing support	provided the technical guidance and editing support	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Review & Editing	YES
5489704	28706531	SAA	2	gathered the literature and contributed in writing the different sections	gathered the literature and contributed in writing the different sections	Wrote the paper	Writing - Original Draft	YES
5489704	28706531	SF	2	conceived the idea of the review and prepared the initial outline and wrote the first draft|had major and equal contribution in overall preparation of manuscript|gathered the literature and contributed in writing the different sections	conceived the idea of the review and prepared the initial outline and wrote the first draft	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5489704	28706531	SF	2	conceived the idea of the review and prepared the initial outline and wrote the first draft|had major and equal contribution in overall preparation of manuscript|gathered the literature and contributed in writing the different sections	had major and equal contribution in overall preparation of manuscript	Wrote the paper	Writing - Original Draft	YES
5489704	28706531	SF	2	conceived the idea of the review and prepared the initial outline and wrote the first draft|had major and equal contribution in overall preparation of manuscript|gathered the literature and contributed in writing the different sections	gathered the literature and contributed in writing the different sections	Wrote the paper	Writing - Original Draft	YES
5489704	28706531	SeS	2	gathered the literature and contributed in writing the different sections	gathered the literature and contributed in writing the different sections	Wrote the paper	Writing - Original Draft	YES
5489704	28706531	ShS	2	gathered the literature and contributed in writing the different sections	gathered the literature and contributed in writing the different sections	Wrote the paper	Writing - Original Draft	YES
5489704	28706531	UN	2	conceived the idea of the review and prepared the initial outline and wrote the first draft|had major and equal contribution in overall preparation of manuscript	conceived the idea of the review and prepared the initial outline and wrote the first draft	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5489704	28706531	UN	2	conceived the idea of the review and prepared the initial outline and wrote the first draft|had major and equal contribution in overall preparation of manuscript	had major and equal contribution in overall preparation of manuscript	Wrote the paper	Writing - Original Draft	YES
5489704	28706531	WN	2	provided the technical guidance and editing support	provided the technical guidance and editing support	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Review & Editing	YES
3551669	23286206	DM	7	Participated in analysis and interpretations of the findings, reviewed the manuscript	Participated in analysis and interpretations of the findings, reviewed the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
3551669	23286206	FA	7	supervision of the study, consultation, follow up and reviewed the manuscript	supervision of the study, consultation, follow up and reviewed the manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
3551669	23286206	GF	7	Participated in conception and design of the study, analysis and interpretations of the findings, drafting the manuscript and write up	Participated in conception and design of the study, analysis and interpretations of the findings, drafting the manuscript and write up	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
3551669	23286206	GY	7	Supervision of the study, analysis and interpretations of the findings, reviewed the manuscript	Supervision of the study, analysis and interpretations of the findings, reviewed the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Supervision|Writing - Review & Editing	YES
3551669	23286206	MA	7	supervision of the study, consultation, follow up and reviewed the manuscript	supervision of the study, consultation, follow up and reviewed the manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
3551669	23286206	YW	7	Participated in conception and design of the study, data collection, analysis and interpretations of the findings, reviewed the manuscript	Participated in conception and design of the study, data collection, analysis and interpretations of the findings, reviewed the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Review & Editing	YES
4401752	25886273	SD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Code writing	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401752	25886273	SD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Code writing	Performed the experiments	Performed the experiments	Investigation	YES
4401752	25886273	SD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Code writing	Analyzed the data	Analyzed the data	Formal analysis	YES
4401752	25886273	SD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Code writing	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401752	25886273	SD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Code writing	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401752	25886273	SD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Code writing	Code writing	Wrote the paper	-	YES
4401752	25886273	SM	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401752	25886273	SM	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5508304	28713569	All authors	1	Participated in research design|Wrote or contributed to the writing of the manuscript	Participated in research design	Conceived and designed the experiments	-	YES
5508304	28713569	All authors	1	Participated in research design|Wrote or contributed to the writing of the manuscript	Wrote or contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
3551683	23035865	AB	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3551683	23035865	All authors	2	design the study	design the study	Conceived and designed the experiments	Methodology	YES
3551683	23035865	FHW	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3551683	23035865	MLI	2	collected and analyzed the data	collected and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3551683	23035865	NB	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3551683	23035865	PA	2	collected and analyzed the data|wrote the manuscript	collected and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3551683	23035865	PA	2	collected and analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3551683	23035865	RO	2	collected and analyzed the data	collected and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3551683	23035865	SF	2	analyzed the data, made substantial contribution to the discussion, and reviewed the final version of the manuscript	analyzed the data, made substantial contribution to the discussion, and reviewed the final version of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4485906	26137586	AA	2	conceived and designed the study|developed the methodology|acquired data|analyzed and/or interpreted data	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4485906	26137586	AA	2	conceived and designed the study|developed the methodology|acquired data|analyzed and/or interpreted data	developed the methodology	Performed the experiments	Methodology	YES
4485906	26137586	AA	2	conceived and designed the study|developed the methodology|acquired data|analyzed and/or interpreted data	acquired data	Performed the experiments	Investigation	YES
4485906	26137586	AA	2	conceived and designed the study|developed the methodology|acquired data|analyzed and/or interpreted data	analyzed and/or interpreted data	Analyzed the data	Formal analysis	YES
4485906	26137586	ALT	2	conceived and designed the study|developed the methodology|acquired data|analyzed and/or interpreted data	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4485906	26137586	ALT	2	conceived and designed the study|developed the methodology|acquired data|analyzed and/or interpreted data	developed the methodology	Performed the experiments	Methodology	YES
4485906	26137586	ALT	2	conceived and designed the study|developed the methodology|acquired data|analyzed and/or interpreted data	acquired data	Performed the experiments	Investigation	YES
4485906	26137586	ALT	2	conceived and designed the study|developed the methodology|acquired data|analyzed and/or interpreted data	analyzed and/or interpreted data	Analyzed the data	Formal analysis	YES
4485906	26137586	All authors	2	wrote and provided final approval of the manuscript	wrote and provided final approval of the manuscript	Wrote the paper	Writing - Original Draft	YES
4485906	26137586	BL	2	developed the methodology|acquired data	developed the methodology	Performed the experiments	Methodology	YES
4485906	26137586	BL	2	developed the methodology|acquired data	acquired data	Performed the experiments	Investigation	YES
4485906	26137586	CS	2	analyzed and/or interpreted data	analyzed and/or interpreted data	Analyzed the data	Formal analysis	YES
4485906	26137586	DF	2	developed the methodology|analyzed and/or interpreted data	developed the methodology	Performed the experiments	Methodology	YES
4485906	26137586	DF	2	developed the methodology|analyzed and/or interpreted data	analyzed and/or interpreted data	Analyzed the data	Formal analysis	YES
4485906	26137586	LB	2	conceived and designed the study|developed the methodology|acquired data|analyzed and/or interpreted data	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4485906	26137586	LB	2	conceived and designed the study|developed the methodology|acquired data|analyzed and/or interpreted data	developed the methodology	Performed the experiments	Methodology	YES
4485906	26137586	LB	2	conceived and designed the study|developed the methodology|acquired data|analyzed and/or interpreted data	acquired data	Performed the experiments	Investigation	YES
4485906	26137586	LB	2	conceived and designed the study|developed the methodology|acquired data|analyzed and/or interpreted data	analyzed and/or interpreted data	Analyzed the data	Formal analysis	YES
4485906	26137586	LG	2	developed the methodology|acquired data|analyzed and/or interpreted data	developed the methodology	Performed the experiments	Methodology	YES
4485906	26137586	LG	2	developed the methodology|acquired data|analyzed and/or interpreted data	acquired data	Performed the experiments	Investigation	YES
4485906	26137586	LG	2	developed the methodology|acquired data|analyzed and/or interpreted data	analyzed and/or interpreted data	Analyzed the data	Formal analysis	YES
4485906	26137586	NK	2	analyzed and/or interpreted data	analyzed and/or interpreted data	Analyzed the data	Formal analysis	YES
4485906	26137586	RAV	2	conceived and designed the study|developed the methodology|acquired data|analyzed and/or interpreted data	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4485906	26137586	RAV	2	conceived and designed the study|developed the methodology|acquired data|analyzed and/or interpreted data	developed the methodology	Performed the experiments	Methodology	YES
4485906	26137586	RAV	2	conceived and designed the study|developed the methodology|acquired data|analyzed and/or interpreted data	acquired data	Performed the experiments	Investigation	YES
4485906	26137586	RAV	2	conceived and designed the study|developed the methodology|acquired data|analyzed and/or interpreted data	analyzed and/or interpreted data	Analyzed the data	Formal analysis	YES
4485906	26137586	SS	2	analyzed and/or interpreted data	analyzed and/or interpreted data	Analyzed the data	Formal analysis	YES
5134283	27905873	BJZ	2	conceived the study and participated in its design and coordination|wrote the manuscript	conceived the study and participated in its design and coordination	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
5134283	27905873	BJZ	2	conceived the study and participated in its design and coordination|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5134283	27905873	CAVJ	2	conceived the study and participated in its design and coordination|carried out the laboratory work|performed the bioinformatics analysis|wrote the manuscript	conceived the study and participated in its design and coordination	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
5134283	27905873	CAVJ	2	conceived the study and participated in its design and coordination|carried out the laboratory work|performed the bioinformatics analysis|wrote the manuscript	carried out the laboratory work	Performed the experiments	Investigation	YES
5134283	27905873	CAVJ	2	conceived the study and participated in its design and coordination|carried out the laboratory work|performed the bioinformatics analysis|wrote the manuscript	performed the bioinformatics analysis	Performed the experiments	Formal analysis|Investigation	YES
5134283	27905873	CAVJ	2	conceived the study and participated in its design and coordination|carried out the laboratory work|performed the bioinformatics analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5134283	27905873	DSV	2	performed the bioinformatics analysis	performed the bioinformatics analysis	Performed the experiments	Formal analysis|Investigation	YES
5134283	27905873	JALvK	2	conceived the study and participated in its design and coordination|wrote the manuscript	conceived the study and participated in its design and coordination	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
5134283	27905873	JALvK	2	conceived the study and participated in its design and coordination|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5134283	27905873	LF	2	performed the bioinformatics analysis	performed the bioinformatics analysis	Performed the experiments	Formal analysis|Investigation	YES
5134283	27905873	SS	2	conceived the study and participated in its design and coordination	conceived the study and participated in its design and coordination	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
5489742	28706526	All authors	2	contributed to the manuscript text|read and approved the manuscript	contributed to the manuscript text	Wrote the paper	Writing - Original Draft	YES
5489742	28706526	All authors	2	contributed to the manuscript text|read and approved the manuscript	read and approved the manuscript	-	-	NO
5489742	28706526	JD	2	drafted the pathology section	drafted the pathology section	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5489742	28706526	JF	2	prepared the section on future prospects as well as edited the article	prepared the section on future prospects as well as edited the article	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5489742	28706526	MR	2	wrote the section on breeding aspects	wrote the section on breeding aspects	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5489742	28706526	SB	2	drafted the pathology section	drafted the pathology section	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5489742	28706526	SK	2	prepared the sections on introduction, molecular markers, and genomics	prepared the sections on introduction, molecular markers, and genomics	Performed the experiments	Investigation	YES
5489742	28706526	SS	2	contributed to the molecular markers and marker assisted selection	contributed to the molecular markers and marker assisted selection	Performed the experiments	Investigation	YES
4401753	25884630	CX	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401753	25884630	JS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401753	25884630	KS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401753	25884630	KS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401753	25884630	KS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401753	25884630	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401753	25884630	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401753	25884630	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401753	25884630	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3560153	23286882	AD	2	performed facs analysis	performed facs analysis	Performed the experiments	Investigation	YES
3560153	23286882	BE	2	adapted the system to large-scale screening	adapted the system to large-scale screening	Performed the experiments	Investigation	YES
3560153	23286882	BF	2	conceived and designed the experiments and drafted the manuscript	conceived and designed the experiments and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
3560153	23286882	CS	2	conceived and designed the experiments and drafted the manuscript	conceived and designed the experiments and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
3560153	23286882	DVY	2	performed small-scale experiments with lentiviral vectors and antiviral drugs	performed small-scale experiments with lentiviral vectors and antiviral drugs	Performed the experiments	Investigation	YES
3560153	23286882	KR	2	performed small-scale experiments with lentiviral vectors and antiviral drugs|adapted the system to large-scale screening	performed small-scale experiments with lentiviral vectors and antiviral drugs	Performed the experiments	Investigation	YES
3560153	23286882	KR	2	performed small-scale experiments with lentiviral vectors and antiviral drugs|adapted the system to large-scale screening	adapted the system to large-scale screening	Performed the experiments	Investigation	YES
3560153	23286882	MMP	2	performed small-scale experiments with lentiviral vectors and antiviral drugs	performed small-scale experiments with lentiviral vectors and antiviral drugs	Performed the experiments	Investigation	YES
3560153	23286882	PVS	2	performed small-scale experiments with lentiviral vectors and antiviral drugs	performed small-scale experiments with lentiviral vectors and antiviral drugs	Performed the experiments	Investigation	YES
3560153	23286882	VSP	2	conceived and designed the experiments and drafted the manuscript	conceived and designed the experiments and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
5625152	28971612	FH	1	Study conception and design|Data acquisition|Data analysis|Data interpretation|Manuscript drafting and revising	Study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5625152	28971612	FH	1	Study conception and design|Data acquisition|Data analysis|Data interpretation|Manuscript drafting and revising	Data acquisition	Performed the experiments	Investigation	YES
5625152	28971612	FH	1	Study conception and design|Data acquisition|Data analysis|Data interpretation|Manuscript drafting and revising	Data analysis	Analyzed the data	Formal analysis	YES
5625152	28971612	FH	1	Study conception and design|Data acquisition|Data analysis|Data interpretation|Manuscript drafting and revising	Data interpretation	Analyzed the data	Formal analysis	YES
5625152	28971612	FH	1	Study conception and design|Data acquisition|Data analysis|Data interpretation|Manuscript drafting and revising	Manuscript drafting and revising	Wrote the paper	Writing - Original Draft	YES
5625152	28971612	MH	1	Study conception and design|Data analysis|Data interpretation|Manuscript drafting and revising	Study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5625152	28971612	MH	1	Study conception and design|Data analysis|Data interpretation|Manuscript drafting and revising	Data analysis	Analyzed the data	Formal analysis	YES
5625152	28971612	MH	1	Study conception and design|Data analysis|Data interpretation|Manuscript drafting and revising	Data interpretation	Analyzed the data	Formal analysis	YES
5625152	28971612	MH	1	Study conception and design|Data analysis|Data interpretation|Manuscript drafting and revising	Manuscript drafting and revising	Wrote the paper	Writing - Original Draft	YES
5625152	28971612	TV	1	Study conception and design|Data analysis|Data interpretation|Manuscript drafting and revising	Study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5625152	28971612	TV	1	Study conception and design|Data analysis|Data interpretation|Manuscript drafting and revising	Data analysis	Analyzed the data	Formal analysis	YES
5625152	28971612	TV	1	Study conception and design|Data analysis|Data interpretation|Manuscript drafting and revising	Data interpretation	Analyzed the data	Formal analysis	YES
5625152	28971612	TV	1	Study conception and design|Data analysis|Data interpretation|Manuscript drafting and revising	Manuscript drafting and revising	Wrote the paper	Writing - Original Draft	YES
5491607	28713397	JD	2	initiated the study, supervised the study, provided laboratory and field materials needed for the study, review and edited manuscript drafts	initiated the study, supervised the study, provided laboratory and field materials needed for the study, review and edited manuscript drafts	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Investigation|Resources|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
5491607	28713397	OO	2	the first author|modified the study design, conducted the study, analyzed and interpreted the data, and drafted the manuscript	the first author	-	-	NO
5491607	28713397	OO	2	the first author|modified the study design, conducted the study, analyzed and interpreted the data, and drafted the manuscript	modified the study design, conducted the study, analyzed and interpreted the data, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
4236089	25431502	All authors	2	have given approval to the final version of the manuscript	have given approval to the final version of the manuscript	-	-	NO
4236089	25431502	The authors	2	declare no competing financial interest	declare no competing financial interest	-	-	NO
5625153	28971603	A.N.	2	participated in research design|conducted experiments|performed data analysis|wrote or contributed to the writing of the manuscript	participated in research design	Conceived and designed the experiments	-	YES
5625153	28971603	A.N.	2	participated in research design|conducted experiments|performed data analysis|wrote or contributed to the writing of the manuscript	conducted experiments	Performed the experiments	Investigation	YES
5625153	28971603	A.N.	2	participated in research design|conducted experiments|performed data analysis|wrote or contributed to the writing of the manuscript	performed data analysis	Analyzed the data	Formal analysis	YES
5625153	28971603	A.N.	2	participated in research design|conducted experiments|performed data analysis|wrote or contributed to the writing of the manuscript	wrote or contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5625153	28971603	B.B.	2	conducted experiments	conducted experiments	Performed the experiments	Investigation	YES
5625153	28971603	H.W.	2	participated in research design|conducted experiments	participated in research design	Conceived and designed the experiments	-	YES
5625153	28971603	H.W.	2	participated in research design|conducted experiments	conducted experiments	Performed the experiments	Investigation	YES
5625153	28971603	K.S.M.	2	participated in research design|conducted experiments|performed data analysis|wrote or contributed to the writing of the manuscript	participated in research design	Conceived and designed the experiments	-	YES
5625153	28971603	K.S.M.	2	participated in research design|conducted experiments|performed data analysis|wrote or contributed to the writing of the manuscript	conducted experiments	Performed the experiments	Investigation	YES
5625153	28971603	K.S.M.	2	participated in research design|conducted experiments|performed data analysis|wrote or contributed to the writing of the manuscript	performed data analysis	Analyzed the data	Formal analysis	YES
5625153	28971603	K.S.M.	2	participated in research design|conducted experiments|performed data analysis|wrote or contributed to the writing of the manuscript	wrote or contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5625153	28971603	S.B.	2	conducted experiments|wrote or contributed to the writing of the manuscript	conducted experiments	Performed the experiments	Investigation	YES
5625153	28971603	S.B.	2	conducted experiments|wrote or contributed to the writing of the manuscript	wrote or contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5135748	27912729	AP	2	provided bioinformatics support, wrote or edited sections of the manuscript associated with bioinformatics tools, and edited the manuscript	provided bioinformatics support, wrote or edited sections of the manuscript associated with bioinformatics tools, and edited the manuscript	Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5135748	27912729	AR	2	provided human and material resources for the work and reviewed the manuscript	provided human and material resources for the work and reviewed the manuscript	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Review & Editing	YES
5135748	27912729	CB	2	performed the hqsnv analysis|analyzed the content of the 93 kb invertible segment, obtained cog data, and prepared the figure|interpreted the data, wrote, and edited the manuscript	performed the hqsnv analysis	Performed the experiments	Investigation	YES
5135748	27912729	CB	2	performed the hqsnv analysis|analyzed the content of the 93 kb invertible segment, obtained cog data, and prepared the figure|interpreted the data, wrote, and edited the manuscript	analyzed the content of the 93 kb invertible segment, obtained cog data, and prepared the figure	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
5135748	27912729	CB	2	performed the hqsnv analysis|analyzed the content of the 93 kb invertible segment, obtained cog data, and prepared the figure|interpreted the data, wrote, and edited the manuscript	interpreted the data, wrote, and edited the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5135748	27912729	CG	2	performed pcr for chromosomal inversions and plasmid genes	performed pcr for chromosomal inversions and plasmid genes	Performed the experiments	Investigation	YES
5135748	27912729	CGC	2	designed the experiments|analyzed and annotated the genomes|performed the hqsnv analysis|performed pcr for chromosomal inversions and plasmid genes|interpreted the data, wrote, and edited the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5135748	27912729	CGC	2	designed the experiments|analyzed and annotated the genomes|performed the hqsnv analysis|performed pcr for chromosomal inversions and plasmid genes|interpreted the data, wrote, and edited the manuscript	analyzed and annotated the genomes	Analyzed the data	Formal analysis	YES
5135748	27912729	CGC	2	designed the experiments|analyzed and annotated the genomes|performed the hqsnv analysis|performed pcr for chromosomal inversions and plasmid genes|interpreted the data, wrote, and edited the manuscript	performed the hqsnv analysis	Performed the experiments	Investigation	YES
5135748	27912729	CGC	2	designed the experiments|analyzed and annotated the genomes|performed the hqsnv analysis|performed pcr for chromosomal inversions and plasmid genes|interpreted the data, wrote, and edited the manuscript	performed pcr for chromosomal inversions and plasmid genes	Performed the experiments	Investigation	YES
5135748	27912729	CGC	2	designed the experiments|analyzed and annotated the genomes|performed the hqsnv analysis|performed pcr for chromosomal inversions and plasmid genes|interpreted the data, wrote, and edited the manuscript	interpreted the data, wrote, and edited the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5135748	27912729	ENT	2	designed the experiments|interpreted the data, wrote, and edited the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5135748	27912729	ENT	2	designed the experiments|interpreted the data, wrote, and edited the manuscript	interpreted the data, wrote, and edited the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5135748	27912729	MW	2	designed the experiments|sequenced and closed the genomes|analyzed and annotated the genomes|performed the hqsnv analysis	designed the experiments	Conceived and designed the experiments	Methodology	YES
5135748	27912729	MW	2	designed the experiments|sequenced and closed the genomes|analyzed and annotated the genomes|performed the hqsnv analysis	sequenced and closed the genomes	Performed the experiments	Investigation	YES
5135748	27912729	MW	2	designed the experiments|sequenced and closed the genomes|analyzed and annotated the genomes|performed the hqsnv analysis	analyzed and annotated the genomes	Analyzed the data	Formal analysis	YES
5135748	27912729	MW	2	designed the experiments|sequenced and closed the genomes|analyzed and annotated the genomes|performed the hqsnv analysis	performed the hqsnv analysis	Performed the experiments	Investigation	YES
4401754	25885434	GZ	PLoS5	Performed the experiments|Read, commented and approved the final version of the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4401754	25885434	GZ	PLoS5	Performed the experiments|Read, commented and approved the final version of the manuscript	Read, commented and approved the final version of the manuscript	-	-	NO
4401754	25885434	JC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Read, commented and approved the final version of the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401754	25885434	JC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Read, commented and approved the final version of the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4401754	25885434	JC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Read, commented and approved the final version of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4401754	25885434	JC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Read, commented and approved the final version of the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401754	25885434	JC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Read, commented and approved the final version of the manuscript	Read, commented and approved the final version of the manuscript	-	-	NO
4401754	25885434	JDH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Read, commented and approved the final version of the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401754	25885434	JDH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Read, commented and approved the final version of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4401754	25885434	JDH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Read, commented and approved the final version of the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401754	25885434	JDH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Read, commented and approved the final version of the manuscript	Read, commented and approved the final version of the manuscript	-	-	NO
4401754	25885434	ML	PLoS5	Performed the experiments|Read, commented and approved the final version of the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4401754	25885434	ML	PLoS5	Performed the experiments|Read, commented and approved the final version of the manuscript	Read, commented and approved the final version of the manuscript	-	-	NO
4401754	25885434	RL	PLoS5	Read, commented and approved the final version of the manuscript	Read, commented and approved the final version of the manuscript	-	-	NO
4401754	25885434	SL	PLoS5	Performed the experiments|Read, commented and approved the final version of the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4401754	25885434	SL	PLoS5	Performed the experiments|Read, commented and approved the final version of the manuscript	Read, commented and approved the final version of the manuscript	-	-	NO
4401754	25885434	WX	PLoS5	Performed the experiments|Read, commented and approved the final version of the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4401754	25885434	WX	PLoS5	Performed the experiments|Read, commented and approved the final version of the manuscript	Read, commented and approved the final version of the manuscript	-	-	NO
4401754	25885434	XL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Read, commented and approved the final version of the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401754	25885434	XL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Read, commented and approved the final version of the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4401754	25885434	XL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Read, commented and approved the final version of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4401754	25885434	XL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Read, commented and approved the final version of the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401754	25885434	XL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Read, commented and approved the final version of the manuscript	Read, commented and approved the final version of the manuscript	-	-	NO
4401754	25885434	ZD	PLoS5	Performed the experiments|Analyzed the data|Read, commented and approved the final version of the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4401754	25885434	ZD	PLoS5	Performed the experiments|Analyzed the data|Read, commented and approved the final version of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4401754	25885434	ZD	PLoS5	Performed the experiments|Analyzed the data|Read, commented and approved the final version of the manuscript	Read, commented and approved the final version of the manuscript	-	-	NO
4401754	25885434	ZW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Read, commented and approved the final version of the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401754	25885434	ZW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Read, commented and approved the final version of the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4401754	25885434	ZW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Read, commented and approved the final version of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4401754	25885434	ZW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Read, commented and approved the final version of the manuscript	Read, commented and approved the final version of the manuscript	-	-	NO
3576311	23347647	AC	2	reviewed medical records and provided information to validate the use of the chosen analytical methods	reviewed medical records and provided information to validate the use of the chosen analytical methods	Performed the experiments	Validation	YES
3576311	23347647	AL	2	reviewed medical records and provided information to validate the use of the chosen analytical methods	reviewed medical records and provided information to validate the use of the chosen analytical methods	Performed the experiments	Validation	YES
3576311	23347647	AP	2	screened medical records and contributed important information to the methods section	screened medical records and contributed important information to the methods section	Performed the experiments	Investigation	YES
3576311	23347647	KR	2	prepared drafts of the report and reviewed and edited the final manuscript	prepared drafts of the report and reviewed and edited the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3576311	23347647	KW	2	reviewed medical records and provided information to validate the use of the chosen analytical methods	reviewed medical records and provided information to validate the use of the chosen analytical methods	Performed the experiments	Validation	YES
3576311	23347647	NH	2	reviewed medical records and provided information to validate the use of the chosen analytical methods	reviewed medical records and provided information to validate the use of the chosen analytical methods	Performed the experiments	Validation	YES
3576311	23347647	SN	2	screened medical records and contributed important information to the methods section	screened medical records and contributed important information to the methods section	Performed the experiments	Investigation	YES
3576311	23347647	WM	2	prepared drafts of the report and reviewed and edited the final manuscript	prepared drafts of the report and reviewed and edited the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5491614	28713401	FQ	2	designed and revised the manuscript	designed and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Review & Editing	YES
5491614	28713401	HW	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3598834	23442332	AA	2	assisted in data collection and reviewed the initial and final drafts of the manuscript|assisted in data collection and reviewed the initial and final drafts of the manuscript|interpreted the results, and reviewed the initial and final drafts of the manuscript|interpreted the results, and reviewed the initial and final drafts of the manuscript	assisted in data collection and reviewed the initial and final drafts of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
3598834	23442332	AA	2	assisted in data collection and reviewed the initial and final drafts of the manuscript|assisted in data collection and reviewed the initial and final drafts of the manuscript|interpreted the results, and reviewed the initial and final drafts of the manuscript|interpreted the results, and reviewed the initial and final drafts of the manuscript	assisted in data collection and reviewed the initial and final drafts of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
3598834	23442332	AA	2	assisted in data collection and reviewed the initial and final drafts of the manuscript|assisted in data collection and reviewed the initial and final drafts of the manuscript|interpreted the results, and reviewed the initial and final drafts of the manuscript|interpreted the results, and reviewed the initial and final drafts of the manuscript	interpreted the results, and reviewed the initial and final drafts of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
3598834	23442332	AA	2	assisted in data collection and reviewed the initial and final drafts of the manuscript|assisted in data collection and reviewed the initial and final drafts of the manuscript|interpreted the results, and reviewed the initial and final drafts of the manuscript|interpreted the results, and reviewed the initial and final drafts of the manuscript	interpreted the results, and reviewed the initial and final drafts of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
3598834	23442332	AM	2	was the primary researcher, conceived the study, designed, participated in data collection, conducted data analysis, drafted and finalized the manuscript for publication|interpreted the results, and reviewed the initial and final drafts of the manuscript	was the primary researcher, conceived the study, designed, participated in data collection, conducted data analysis, drafted and finalized the manuscript for publication	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
3598834	23442332	AM	2	was the primary researcher, conceived the study, designed, participated in data collection, conducted data analysis, drafted and finalized the manuscript for publication|interpreted the results, and reviewed the initial and final drafts of the manuscript	interpreted the results, and reviewed the initial and final drafts of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
3598834	23442332	MD	2	assisted in data collection and reviewed the initial and final drafts of the manuscript|interpreted the results, and reviewed the initial and final drafts of the manuscript	assisted in data collection and reviewed the initial and final drafts of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
3598834	23442332	MD	2	assisted in data collection and reviewed the initial and final drafts of the manuscript|interpreted the results, and reviewed the initial and final drafts of the manuscript	interpreted the results, and reviewed the initial and final drafts of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
4401755	25885680	AS	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401755	25885680	HK	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401755	25885680	KI	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401755	25885680	MH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401755	25885680	MH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401755	25885680	MH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401755	25885680	NA	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401755	25885680	PAJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401755	25885680	PAJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401755	25885680	PAJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401755	25885680	PAJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401755	25885680	PAJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401755	25885680	PS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401755	25885680	PS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401755	25885680	PS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401755	25885680	PS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401755	25885680	PS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401755	25885680	RRN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401755	25885680	RRN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401755	25885680	RRN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401755	25885680	RRN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401755	25885680	RRN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401755	25885680	SA	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401755	25885680	SA	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401755	25885680	SKS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401755	25885680	ST	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401755	25885680	ST	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401755	25885680	ST	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401755	25885680	ST	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401755	25885680	ST	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401755	25885680	TI	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401755	25885680	YO	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5135761	27914481	DG	2	performed all the calculations|analyzed results and wrote the manuscript	performed all the calculations	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5135761	27914481	DG	2	performed all the calculations|analyzed results and wrote the manuscript	analyzed results and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5135761	27914481	MP	2	conceived the study and supervised the first author|analyzed results and wrote the manuscript	conceived the study and supervised the first author	Conceived and designed the experiments	Conceptualization|Supervision	YES
5135761	27914481	MP	2	conceived the study and supervised the first author|analyzed results and wrote the manuscript	analyzed results and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4534682	26288841	A.H.	2	planned and designed the experiments|conducted the experiments|interpreted data	planned and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4534682	26288841	A.H.	2	planned and designed the experiments|conducted the experiments|interpreted data	conducted the experiments	Performed the experiments	Investigation	YES
4534682	26288841	A.H.	2	planned and designed the experiments|conducted the experiments|interpreted data	interpreted data	Analyzed the data	Formal analysis	YES
4534682	26288841	G.S.	2	planned and designed the experiments|interpreted data	planned and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4534682	26288841	G.S.	2	planned and designed the experiments|interpreted data	interpreted data	Analyzed the data	Formal analysis	YES
4534682	26288841	H.R.	2	improved the published synthesis and product analysis of nbd-azm	improved the published synthesis and product analysis of nbd-azm	-	-	NO
4534682	26288841	J.M.	2	planned and designed the experiments|conducted the experiments|interpreted data	planned and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4534682	26288841	J.M.	2	planned and designed the experiments|conducted the experiments|interpreted data	conducted the experiments	Performed the experiments	Investigation	YES
4534682	26288841	J.M.	2	planned and designed the experiments|conducted the experiments|interpreted data	interpreted data	Analyzed the data	Formal analysis	YES
4534682	26288841	J.O.	2	planned and designed the experiments|conducted the experiments|interpreted data	planned and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4534682	26288841	J.O.	2	planned and designed the experiments|conducted the experiments|interpreted data	conducted the experiments	Performed the experiments	Investigation	YES
4534682	26288841	J.O.	2	planned and designed the experiments|conducted the experiments|interpreted data	interpreted data	Analyzed the data	Formal analysis	YES
4534682	26288841	J.P.	2	planned and designed the experiments|interpreted data	planned and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4534682	26288841	J.P.	2	planned and designed the experiments|interpreted data	interpreted data	Analyzed the data	Formal analysis	YES
4534682	26288841	L.L.	2	planned and designed the experiments|conducted the experiments|interpreted data|drafted and revised the manuscript	planned and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4534682	26288841	L.L.	2	planned and designed the experiments|conducted the experiments|interpreted data|drafted and revised the manuscript	conducted the experiments	Performed the experiments	Investigation	YES
4534682	26288841	L.L.	2	planned and designed the experiments|conducted the experiments|interpreted data|drafted and revised the manuscript	interpreted data	Analyzed the data	Formal analysis	YES
4534682	26288841	L.L.	2	planned and designed the experiments|conducted the experiments|interpreted data|drafted and revised the manuscript	drafted and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4534682	26288841	M.D.B.	2	improved the published synthesis and product analysis of nbd-azm	improved the published synthesis and product analysis of nbd-azm	-	-	NO
4534682	26288841	M.E.H.	2	conducted the experiments|interpreted data	conducted the experiments	Performed the experiments	Investigation	YES
4534682	26288841	M.E.H.	2	conducted the experiments|interpreted data	interpreted data	Analyzed the data	Formal analysis	YES
4534682	26288841	M.K.	2	conducted the experiments	conducted the experiments	Performed the experiments	Investigation	YES
4534682	26288841	M.R.	2	interpreted the electron microscopy studies	interpreted the electron microscopy studies	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4534682	26288841	P.N.	2	planned and designed the experiments|conducted the experiments|interpreted data	planned and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4534682	26288841	P.N.	2	planned and designed the experiments|conducted the experiments|interpreted data	conducted the experiments	Performed the experiments	Investigation	YES
4534682	26288841	P.N.	2	planned and designed the experiments|conducted the experiments|interpreted data	interpreted data	Analyzed the data	Formal analysis	YES
4534682	26288841	Q.D.	2	conducted the experiments	conducted the experiments	Performed the experiments	Investigation	YES
4534682	26288841	R.C.	2	conducted the experiments	conducted the experiments	Performed the experiments	Investigation	YES
4534682	26288841	V.N.	2	planned and designed the experiments|interpreted data|drafted and revised the manuscript	planned and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4534682	26288841	V.N.	2	planned and designed the experiments|interpreted data|drafted and revised the manuscript	interpreted data	Analyzed the data	Formal analysis	YES
4534682	26288841	V.N.	2	planned and designed the experiments|interpreted data|drafted and revised the manuscript	drafted and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5491619	28713394	CJ	PLoS52	performed the experiments|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5491619	28713394	CJ	PLoS52	performed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5491619	28713394	HC	PLoS52	proofread this manuscript	proofread this manuscript	-	-	NO
5491619	28713394	HZ	PLoS52	proofread this manuscript	proofread this manuscript	-	-	NO
5491619	28713394	JH	PLoS52	proofread this manuscript	proofread this manuscript	-	-	NO
5491619	28713394	KL	PLoS52	proofread this manuscript	proofread this manuscript	-	-	NO
5491619	28713394	SZ	PLoS52	proofread this manuscript	proofread this manuscript	-	-	NO
5491619	28713394	XH	PLoS52	designed the research|performed the experiments|wrote the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
5491619	28713394	XH	PLoS52	designed the research|performed the experiments|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5491619	28713394	XH	PLoS52	designed the research|performed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5491619	28713394	XX	PLoS52	proofread this manuscript	proofread this manuscript	-	-	NO
5491619	28713394	YC	PLoS52	proofread this manuscript	proofread this manuscript	-	-	NO
5491619	28713394	YW	PLoS52	proofread this manuscript	proofread this manuscript	-	-	NO
3606211	23496891	AR	2	were involved in designing and conducting the study|were all involved in the analysis of results, writing and editing of the manuscript	were involved in designing and conducting the study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3606211	23496891	AR	2	were involved in designing and conducting the study|were all involved in the analysis of results, writing and editing of the manuscript	were all involved in the analysis of results, writing and editing of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
3606211	23496891	AT	2	were involved in designing and conducting the study|were all involved in the analysis of results, writing and editing of the manuscript	were involved in designing and conducting the study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3606211	23496891	AT	2	were involved in designing and conducting the study|were all involved in the analysis of results, writing and editing of the manuscript	were all involved in the analysis of results, writing and editing of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
3606211	23496891	JCB	2	were all involved in the analysis of results, writing and editing of the manuscript	were all involved in the analysis of results, writing and editing of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
3606211	23496891	JJV	2	were all involved in the analysis of results, writing and editing of the manuscript	were all involved in the analysis of results, writing and editing of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
3606211	23496891	NP	2	were involved in designing and conducting the study|were all involved in the analysis of results, writing and editing of the manuscript	were involved in designing and conducting the study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3606211	23496891	NP	2	were involved in designing and conducting the study|were all involved in the analysis of results, writing and editing of the manuscript	were all involved in the analysis of results, writing and editing of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
3606211	23496891	PAC	2	were all involved in the analysis of results, writing and editing of the manuscript	were all involved in the analysis of results, writing and editing of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
3606211	23496891	TPF	2	were involved in designing and conducting the study|were all involved in the analysis of results, writing and editing of the manuscript	were involved in designing and conducting the study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3606211	23496891	TPF	2	were involved in designing and conducting the study|were all involved in the analysis of results, writing and editing of the manuscript	were all involved in the analysis of results, writing and editing of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
4401756	25885221	AN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Sampled ant-plant-herbivore descriptors in the laboratory, greenhouse and field|Prepared the scripts used in the analyses	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401756	25885221	AN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Sampled ant-plant-herbivore descriptors in the laboratory, greenhouse and field|Prepared the scripts used in the analyses	Performed the experiments	Performed the experiments	Investigation	YES
4401756	25885221	AN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Sampled ant-plant-herbivore descriptors in the laboratory, greenhouse and field|Prepared the scripts used in the analyses	Analyzed the data	Analyzed the data	Formal analysis	YES
4401756	25885221	AN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Sampled ant-plant-herbivore descriptors in the laboratory, greenhouse and field|Prepared the scripts used in the analyses	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401756	25885221	AN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Sampled ant-plant-herbivore descriptors in the laboratory, greenhouse and field|Prepared the scripts used in the analyses	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401756	25885221	AN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Sampled ant-plant-herbivore descriptors in the laboratory, greenhouse and field|Prepared the scripts used in the analyses	Sampled ant-plant-herbivore descriptors in the laboratory, greenhouse and field	Performed the experiments	Investigation	YES
4401756	25885221	AN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Sampled ant-plant-herbivore descriptors in the laboratory, greenhouse and field|Prepared the scripts used in the analyses	Prepared the scripts used in the analyses	Analyzed the data	Formal analysis	YES
4401756	25885221	JMA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401756	25885221	JMA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401756	25885221	JMA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401756	25885221	LGL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401756	25885221	LGL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401756	25885221	LGL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401756	25885221	PJR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401756	25885221	PJR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401756	25885221	PJR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401756	25885221	RMF	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper|Identification of ant species	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401756	25885221	RMF	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper|Identification of ant species	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401756	25885221	RMF	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper|Identification of ant species	Identification of ant species	Performed the experiments	Investigation	YES
3610245	23347595	All authors	2	substantially contributed to development of all drafts of the manuscript and have read and approved the final draft	substantially contributed to development of all drafts of the manuscript and have read and approved the final draft	Wrote the paper	Writing - Original Draft	YES
4534683	26288847	H.Ka	2	performed the genetic analyses	performed the genetic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4534683	26288847	S.Na	2	designed the study, interpreted the data and wrote the manuscript	designed the study, interpreted the data and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5135796	27912743	KK	2	proposed the statistical model and implemented the program for evaluation|developed fundamental environments for the evaluation using simulation and real data studies|carefully checked equations and other contents in this manuscript	proposed the statistical model and implemented the program for evaluation	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation|Methodology	YES
5135796	27912743	KK	2	proposed the statistical model and implemented the program for evaluation|developed fundamental environments for the evaluation using simulation and real data studies|carefully checked equations and other contents in this manuscript	developed fundamental environments for the evaluation using simulation and real data studies	-	Formal analysis	YES
5135796	27912743	KK	2	proposed the statistical model and implemented the program for evaluation|developed fundamental environments for the evaluation using simulation and real data studies|carefully checked equations and other contents in this manuscript	carefully checked equations and other contents in this manuscript	Wrote the paper	Writing - Review & Editing	YES
5135796	27912743	KM	2	developed fundamental environments for the evaluation using simulation and real data studies|carefully checked equations and other contents in this manuscript	developed fundamental environments for the evaluation using simulation and real data studies	-	Formal analysis	YES
5135796	27912743	KM	2	developed fundamental environments for the evaluation using simulation and real data studies|carefully checked equations and other contents in this manuscript	carefully checked equations and other contents in this manuscript	Wrote the paper	Writing - Review & Editing	YES
5135796	27912743	MN	2	developed fundamental environments for the evaluation using simulation and real data studies|carefully checked equations and other contents in this manuscript	developed fundamental environments for the evaluation using simulation and real data studies	-	Formal analysis	YES
5135796	27912743	MN	2	developed fundamental environments for the evaluation using simulation and real data studies|carefully checked equations and other contents in this manuscript	carefully checked equations and other contents in this manuscript	Wrote the paper	Writing - Review & Editing	YES
5135796	27912743	TM	2	developed fundamental environments for the evaluation using simulation and real data studies|carefully checked equations and other contents in this manuscript	developed fundamental environments for the evaluation using simulation and real data studies	-	Formal analysis	YES
5135796	27912743	TM	2	developed fundamental environments for the evaluation using simulation and real data studies|carefully checked equations and other contents in this manuscript	carefully checked equations and other contents in this manuscript	Wrote the paper	Writing - Review & Editing	YES
5135796	27912743	YK	2	developed fundamental environments for the evaluation using simulation and real data studies|carefully checked equations and other contents in this manuscript	developed fundamental environments for the evaluation using simulation and real data studies	-	Formal analysis	YES
5135796	27912743	YK	2	developed fundamental environments for the evaluation using simulation and real data studies|carefully checked equations and other contents in this manuscript	carefully checked equations and other contents in this manuscript	Wrote the paper	Writing - Review & Editing	YES
5491620	28713399	All authors	2	assisted in critical revision of this manuscript, approve of the version submitted for publication, and have agreed to be accountable for all aspects of the work, including ensuring that all questions regarding the accuracy or integrity of the work are appropriately investigated and resolved	assisted in critical revision of this manuscript, approve of the version submitted for publication, and have agreed to be accountable for all aspects of the work, including ensuring that all questions regarding the accuracy or integrity of the work are appropriately investigated and resolved	Wrote the paper	Writing - Review & Editing	YES
3610248	23351618	BJB	2	conducted the study, interpreted the data, and edited the manuscript	conducted the study, interpreted the data, and edited the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
3610248	23351618	CO	2	conducted the study, interpreted the data, and edited the manuscript	conducted the study, interpreted the data, and edited the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
3610248	23351618	DMS	2	conducted the study, interpreted the data, and edited the manuscript	conducted the study, interpreted the data, and edited the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
3610248	23351618	GFV	2	designed the study, analyzed and interpreted the data, and prepared the manuscript	designed the study, analyzed and interpreted the data, and prepared the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3610248	23351618	GM	2	conducted the study, interpreted the data, and edited the manuscript	conducted the study, interpreted the data, and edited the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
3610248	23351618	GS	2	conducted the study, interpreted the data, and edited the manuscript	conducted the study, interpreted the data, and edited the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
3610248	23351618	JKT	2	designed the study, analyzed and interpreted the data, and prepared the manuscript	designed the study, analyzed and interpreted the data, and prepared the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3610248	23351618	MF	2	conducted the study, interpreted the data, and edited the manuscript	conducted the study, interpreted the data, and edited the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
3610248	23351618	NL	2	conducted the study, interpreted the data, and edited the manuscript	conducted the study, interpreted the data, and edited the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
3610248	23351618	SB	2	conducted the study, interpreted the data, and edited the manuscript	conducted the study, interpreted the data, and edited the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
5625159	28971618	All authors	2	contributed to the interpretation and discussion of the results either at the study analysis or manuscript-writing phase|critically commented on and revised the manuscript	contributed to the interpretation and discussion of the results either at the study analysis or manuscript-writing phase	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5625159	28971618	All authors	2	contributed to the interpretation and discussion of the results either at the study analysis or manuscript-writing phase|critically commented on and revised the manuscript	critically commented on and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5625159	28971618	C.C.	2	performed the statistical data analysis|critically commented on and revised the manuscript	performed the statistical data analysis	Analyzed the data	Formal analysis	YES
5625159	28971618	C.C.	2	performed the statistical data analysis|critically commented on and revised the manuscript	critically commented on and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5625159	28971618	P.M.	2	did the data collection	did the data collection	Performed the experiments	Investigation	YES
5625159	28971618	R.A.	2	designed the study|did the literature review|did the data collection|performed the statistical data analysis	designed the study	Conceived and designed the experiments	Methodology	YES
5625159	28971618	R.A.	2	designed the study|did the literature review|did the data collection|performed the statistical data analysis	did the literature review	-	Formal analysis	YES
5625159	28971618	R.A.	2	designed the study|did the literature review|did the data collection|performed the statistical data analysis	did the data collection	Performed the experiments	Investigation	YES
5625159	28971618	R.A.	2	designed the study|did the literature review|did the data collection|performed the statistical data analysis	performed the statistical data analysis	Analyzed the data	Formal analysis	YES
5625159	28971618	S.S.	2	designed the study|did the literature review|did the data collection|performed the statistical data analysis|critically commented on and revised the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5625159	28971618	S.S.	2	designed the study|did the literature review|did the data collection|performed the statistical data analysis|critically commented on and revised the manuscript	did the literature review	-	Formal analysis	YES
5625159	28971618	S.S.	2	designed the study|did the literature review|did the data collection|performed the statistical data analysis|critically commented on and revised the manuscript	did the data collection	Performed the experiments	Investigation	YES
5625159	28971618	S.S.	2	designed the study|did the literature review|did the data collection|performed the statistical data analysis|critically commented on and revised the manuscript	performed the statistical data analysis	Analyzed the data	Formal analysis	YES
5625159	28971618	S.S.	2	designed the study|did the literature review|did the data collection|performed the statistical data analysis|critically commented on and revised the manuscript	critically commented on and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4401757	25886472	DS	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401757	25886472	DS	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401757	25886472	DS	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401757	25886472	ELT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401757	25886472	ELT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401757	25886472	ELT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401757	25886472	FK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401757	25886472	FK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401757	25886472	FK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401757	25886472	FK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401757	25886472	HK	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401757	25886472	HK	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401757	25886472	HK	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401757	25886472	JE	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401757	25886472	JE	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401757	25886472	JE	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401757	25886472	JWS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401757	25886472	JWS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401757	25886472	JWS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401757	25886472	JWS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401757	25886472	NT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401757	25886472	NT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401757	25886472	NT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401757	25886472	OM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401757	25886472	OM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401757	25886472	OM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401757	25886472	UPD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401757	25886472	UPD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401757	25886472	UPD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401757	25886472	VM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401757	25886472	VM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401757	25886472	VM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3620560	23537147	BC	2	study design	study design	Conceived and designed the experiments	Methodology	YES
3620560	23537147	CB	2	study design	study design	Conceived and designed the experiments	Methodology	YES
3620560	23537147	CM	2	study design	study design	Conceived and designed the experiments	Methodology	YES
3620560	23537147	DW	2	clinical care	clinical care	-	-	NO
3620560	23537147	FT	2	clinical care	clinical care	-	-	NO
3620560	23537147	IRB	2	request supervision, study design, data collection, data analyses and manuscript preparation|preparation and submission, study design, data collection and data analyses|request supervision and clinical care|submission supervision and data analyses	request supervision, study design, data collection, data analyses and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Supervision|Writing - Original Draft	YES
3620560	23537147	IRB	2	request supervision, study design, data collection, data analyses and manuscript preparation|preparation and submission, study design, data collection and data analyses|request supervision and clinical care|submission supervision and data analyses	preparation and submission, study design, data collection and data analyses	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
3620560	23537147	IRB	2	request supervision, study design, data collection, data analyses and manuscript preparation|preparation and submission, study design, data collection and data analyses|request supervision and clinical care|submission supervision and data analyses	request supervision and clinical care	-	Supervision	YES
3620560	23537147	IRB	2	request supervision, study design, data collection, data analyses and manuscript preparation|preparation and submission, study design, data collection and data analyses|request supervision and clinical care|submission supervision and data analyses	submission supervision and data analyses	Analyzed the data	Formal analysis|Supervision	YES
4450297	26090459	Linfeng Xu	2	contributed equally to this work	contributed equally to this work	-	-	NO
4450297	26090459	Yuanzhi Lao	2	contributed equally to this work	contributed equally to this work	-	-	NO
5625160	28971615	All authors	2	contributed to the conception and design of the study, data analysis/interpretation and revision of the manuscript for intellectual content, and provided final approval of the manuscript	contributed to the conception and design of the study, data analysis/interpretation and revision of the manuscript for intellectual content, and provided final approval of the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Methodology|Resources|Writing - Review & Editing	YES
5625160	28971615	JB	2	was the principal investigator of the study	was the principal investigator of the study	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
5139010	27919223	CMM	2	designed the study, performed sample collection, and drafted the manuscript|processed samples|analyzed and interpreted the data	designed the study, performed sample collection, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5139010	27919223	CMM	2	designed the study, performed sample collection, and drafted the manuscript|processed samples|analyzed and interpreted the data	processed samples	Analyzed the data	Data curation	YES
5139010	27919223	CMM	2	designed the study, performed sample collection, and drafted the manuscript|processed samples|analyzed and interpreted the data	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5139010	27919223	CWC	2	analyzed and interpreted the data	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5139010	27919223	GPB	2	provided permission for and access to samples	provided permission for and access to samples	Contributed reagents/materials/analysis tools	Resources	YES
5139010	27919223	KK	2	analyzed and interpreted the data	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5139010	27919223	NDC	2	designed the study, performed sample collection, and drafted the manuscript|analyzed and interpreted the data	designed the study, performed sample collection, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5139010	27919223	NDC	2	designed the study, performed sample collection, and drafted the manuscript|analyzed and interpreted the data	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5139010	27919223	SVD	2	designed the study, performed sample collection, and drafted the manuscript|analyzed and interpreted the data	designed the study, performed sample collection, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5139010	27919223	SVD	2	designed the study, performed sample collection, and drafted the manuscript|analyzed and interpreted the data	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5491621	28713396	All the authors	PLoS52	approved the final manuscript	approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5491621	28713396	JW	PLoS52	analyzed the data|revised the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5491621	28713396	JW	PLoS52	analyzed the data|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5491621	28713396	LW	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5491621	28713396	LW	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5491621	28713396	LW	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5491621	28713396	LW	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5491621	28713396	WW	PLoS52	conceived and designed the experiments|analyzed the data|provided the reagents, materials and analytical tools|revised the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5491621	28713396	WW	PLoS52	conceived and designed the experiments|analyzed the data|provided the reagents, materials and analytical tools|revised the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5491621	28713396	WW	PLoS52	conceived and designed the experiments|analyzed the data|provided the reagents, materials and analytical tools|revised the manuscript	provided the reagents, materials and analytical tools	Contributed reagents/materials/analysis tools	Resources	YES
5491621	28713396	WW	PLoS52	conceived and designed the experiments|analyzed the data|provided the reagents, materials and analytical tools|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5491621	28713396	XS	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
3657294	23675734	All authors	2	have given final approval of the version to be published	have given final approval of the version to be published	-	-	NO
3657294	23675734	MM	2	conceptualized the study, conducted data collection and analysis and wrote the draft manuscript	conceptualized the study, conducted data collection and analysis and wrote the draft manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
3657294	23675734	SM	2	contributed towards the conceptualization of the study, provided input in the analysis, interpretation of the findings and drafting of the manuscript	contributed towards the conceptualization of the study, provided input in the analysis, interpretation of the findings and drafting of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
3657294	23675734	VB	2	contributed towards the conceptualization of the study, provided input in the analysis, interpretation of the findings and drafting of the manuscript	contributed towards the conceptualization of the study, provided input in the analysis, interpretation of the findings and drafting of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
4401759	25886641	LED	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401759	25886641	LED	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401759	25886641	LED	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401759	25886641	LED	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401759	25886641	LED	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401759	25886641	PRK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401759	25886641	PRK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401759	25886641	PRK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401759	25886641	PRK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401759	25886641	PRK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4534756	26287272	All authors	PLoS52	contributed to the discussion and the final draft of the paper	contributed to the discussion and the final draft of the paper	Wrote the paper	Writing - Original Draft	YES
4534756	26287272	B.T.S.	PLoS52	interpreted the results	interpreted the results	Analyzed the data	Formal analysis	YES
4534756	26287272	N.M.R.	PLoS52	conceived the research, conducted the literature search, designed and performed the experiments, compiled the figures and wrote the manuscript|interpreted the results	conceived the research, conducted the literature search, designed and performed the experiments, compiled the figures and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Visualization|Writing - Original Draft	YES
4534756	26287272	N.M.R.	PLoS52	conceived the research, conducted the literature search, designed and performed the experiments, compiled the figures and wrote the manuscript|interpreted the results	interpreted the results	Analyzed the data	Formal analysis	YES
4534756	26287272	P.C.	PLoS52	analysed the data|interpreted the results	analysed the data	Analyzed the data	Formal analysis	YES
4534756	26287272	P.C.	PLoS52	analysed the data|interpreted the results	interpreted the results	Analyzed the data	Formal analysis	YES
4534756	26287272	R.P.	PLoS52	interpreted the results	interpreted the results	Analyzed the data	Formal analysis	YES
4534756	26287272	S.C.	PLoS52	supervised the project	supervised the project	-	Supervision	YES
3658904	23680529	AB	2	carried out data collection, data entry and helped draft the manuscript	carried out data collection, data entry and helped draft the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Investigation|Writing - Original Draft	YES
3658904	23680529	AGC	2	carried out data collection, statistical analysis and drafted the manuscript	carried out data collection, statistical analysis and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3658904	23680529	CAS	2	designed the statistical methods, supervised the statistical analysis and helped draft the manuscript	designed the statistical methods, supervised the statistical analysis and helped draft the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Supervision|Writing - Original Draft	YES
3658904	23680529	GS	2	helped draft the manuscript	helped draft the manuscript	Wrote the paper	Writing - Original Draft	YES
3658904	23680529	JL	2	helped draft the manuscript	helped draft the manuscript	Wrote the paper	Writing - Original Draft	YES
3658904	23680529	PWGM	2	conceived the study, supervised the statistical analysis and helped draft the manuscript	conceived the study, supervised the statistical analysis and helped draft the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Supervision|Writing - Original Draft	YES
4311656	25337896	T.W.	2	contributed equally to this work	contributed equally to this work	-	-	NO
4311656	25337896	X.Y.	2	contributed equally to this work	contributed equally to this work	-	-	NO
5139114	27919227	All authors	2	approved the final manuscript	approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5139114	27919227	HPD	2	conceived and designed the study|wrote the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5139114	27919227	HPD	2	conceived and designed the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5139114	27919227	JG	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5139114	27919227	LC	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5139114	27919227	SB	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5139114	27919227	SHL	2	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5139114	27919227	TJ	2	performed the analysis of pigment data	performed the analysis of pigment data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5139114	27919227	YLD	2	conceived and designed the study|carried out the experiments	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5139114	27919227	YLD	2	conceived and designed the study|carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
4535124	26288810	CY	2	all contributed to the data interpretation and writing aspects of the manuscript|should be considered as making an equal and joint contribution as 1st authors	all contributed to the data interpretation and writing aspects of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4535124	26288810	CY	2	all contributed to the data interpretation and writing aspects of the manuscript|should be considered as making an equal and joint contribution as 1st authors	should be considered as making an equal and joint contribution as 1st authors	-	-	NO
4535124	26288810	KC	2	all contributed to the data interpretation and writing aspects of the manuscript|should be considered as making an equal and joint contribution as 1st authors	all contributed to the data interpretation and writing aspects of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4535124	26288810	KC	2	all contributed to the data interpretation and writing aspects of the manuscript|should be considered as making an equal and joint contribution as 1st authors	should be considered as making an equal and joint contribution as 1st authors	-	-	NO
4535124	26288810	KIM	2	all contributed to the data interpretation and writing aspects of the manuscript	all contributed to the data interpretation and writing aspects of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5491623	28713407	GP	2	helped bioreactor maintenance	helped bioreactor maintenance	-	-	NO
5491623	28713407	GS	2	lead and designed the experiments and performed the biorhizome biomanufacturing, bioprocess engineering and analytical studies	lead and designed the experiments and performed the biorhizome biomanufacturing, bioprocess engineering and analytical studies	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5491623	28713407	KA	2	performed the fluid mechanics	performed the fluid mechanics	Performed the experiments	Investigation	YES
3663662	23659629	All authors	2	have contributed to the acquisition, analysis and interpretation of data and have been involved in drafting and revising the manuscript	have contributed to the acquisition, analysis and interpretation of data and have been involved in drafting and revising the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
3663662	23659629	J. All	2	authors have given final approval of the version to be published and may take public responsibility of the content	authors have given final approval of the version to be published and may take public responsibility of the content	-	-	NO
3668251	23634877	CM	2	assisted in data collection, follow-up the hiv positive patients and reviewed the initial and final drafts of the manuscript	assisted in data collection, follow-up the hiv positive patients and reviewed the initial and final drafts of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
3668251	23634877	EA	2	was the primary researcher, conceived the study, designed, participated in data collection and drafted manuscript	was the primary researcher, conceived the study, designed, participated in data collection and drafted manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Writing - Original Draft	YES
3668251	23634877	FJ	2	assigned the randomization of patients and conducted statistical analysis	assigned the randomization of patients and conducted statistical analysis	Analyzed the data	Formal analysis	YES
3668251	23634877	MR	2	assisted in data collection, follow-up the hiv positive patients and reviewed the initial and final drafts of the manuscript	assisted in data collection, follow-up the hiv positive patients and reviewed the initial and final drafts of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
4401761	25885063	CG	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401761	25885063	CH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401761	25885063	CH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401761	25885063	CH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401761	25885063	CH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401761	25885063	HI	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401761	25885063	HI	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401761	25885063	HO	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401761	25885063	IK	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401761	25885063	LG	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4535158	26288816	CK-Y	2	initiated the research and planned most of the experiments|performed most of the experiments|contributed to the writing of the manuscript	initiated the research and planned most of the experiments	Conceived and designed the experiments	Conceptualization	YES
4535158	26288816	CK-Y	2	initiated the research and planned most of the experiments|performed most of the experiments|contributed to the writing of the manuscript	performed most of the experiments	Performed the experiments	Investigation	YES
4535158	26288816	CK-Y	2	initiated the research and planned most of the experiments|performed most of the experiments|contributed to the writing of the manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
4535158	26288816	CN	2	generated the mouse dkk1 flox/flox strain|contributed to the writing of the manuscript	generated the mouse dkk1 flox/flox strain	Performed the experiments	Investigation	YES
4535158	26288816	CN	2	generated the mouse dkk1 flox/flox strain|contributed to the writing of the manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
4535158	26288816	IM	2	initiated the research and planned most of the experiments|contributed to the writing of the manuscript	initiated the research and planned most of the experiments	Conceived and designed the experiments	Conceptualization	YES
4535158	26288816	IM	2	initiated the research and planned most of the experiments|contributed to the writing of the manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
4535158	26288816	KE	2	generated the mouse dkk1 flox/flox strain	generated the mouse dkk1 flox/flox strain	Performed the experiments	Investigation	YES
4535158	26288816	KM	2	performed most of the experiments	performed most of the experiments	Performed the experiments	Investigation	YES
5625163	28971619	A.O.	2	participated in experimental design|contributed to the editing of the manuscript|contributed to the editing of the manuscript	participated in experimental design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5625163	28971619	A.O.	2	participated in experimental design|contributed to the editing of the manuscript|contributed to the editing of the manuscript	contributed to the editing of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5625163	28971619	A.O.	2	participated in experimental design|contributed to the editing of the manuscript|contributed to the editing of the manuscript	contributed to the editing of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5625163	28971619	C.C.	2	wrote the manuscript|participated in experimental design|contributed to the editing of the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5625163	28971619	C.C.	2	wrote the manuscript|participated in experimental design|contributed to the editing of the manuscript	participated in experimental design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5625163	28971619	C.C.	2	wrote the manuscript|participated in experimental design|contributed to the editing of the manuscript	contributed to the editing of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5625163	28971619	L.A.	2	participated in experimental design|contributed to the editing of the manuscript	participated in experimental design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5625163	28971619	L.A.	2	participated in experimental design|contributed to the editing of the manuscript	contributed to the editing of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5625163	28971619	M.S.	2	participated in experimental design|contributed to the editing of the manuscript	participated in experimental design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5625163	28971619	M.S.	2	participated in experimental design|contributed to the editing of the manuscript	contributed to the editing of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5625163	28971619	N.J.L.	2	contributed to the editing of the manuscript	contributed to the editing of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5625163	28971619	P.M.	2	contributed to the editing of the manuscript	contributed to the editing of the manuscript	Wrote the paper	Writing - Review & Editing	YES
3680009	23721408	ACM	2	were involved in the conception, design and preparation of self-emulsifying oil formulations	were involved in the conception, design and preparation of self-emulsifying oil formulations	Conceived and designed the experiments	Conceptualization	YES
3680009	23721408	All the authors	2	were involved in the preparation and editing of the manuscript	were involved in the preparation and editing of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3680009	23721408	ECO	2	were involved in the conception, design and preparation of self-emulsifying oil formulations	were involved in the conception, design and preparation of self-emulsifying oil formulations	Conceived and designed the experiments	Conceptualization	YES
3680009	23721408	ONC	2	were involved in the conception, design and preparation of self-emulsifying oil formulations	were involved in the conception, design and preparation of self-emulsifying oil formulations	Conceived and designed the experiments	Conceptualization	YES
3680009	23721408	PMA	2	designed and carried out the bioactivity studies	designed and carried out the bioactivity studies	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3680009	23721408	RLC	2	were involved in the conception, design and preparation of self-emulsifying oil formulations	were involved in the conception, design and preparation of self-emulsifying oil formulations	Conceived and designed the experiments	Conceptualization	YES
5491648	28713411	AB	2	carried out the biochemical and molecular/epigenetic studies, data collection, and their analysis	carried out the biochemical and molecular/epigenetic studies, data collection, and their analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5491648	28713411	AS	2	helped in execution of the experimental plan, data analysis, and writing the manuscript	helped in execution of the experimental plan, data analysis, and writing the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5491648	28713411	MA	2	carried out the biochemical and molecular/epigenetic studies, data collection, and their analysis	carried out the biochemical and molecular/epigenetic studies, data collection, and their analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5491648	28713411	SK	2	conceptualized, designed and carried out the epigenetic/ionomic/bioinformatic studies, and wrote/revised the manuscript	conceptualized, designed and carried out the epigenetic/ionomic/bioinformatic studies, and wrote/revised the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5139131	27919246	AL	2	performed phylogenetic studies and the breakpoints distribution statistical analysis, participated in interpretation of results and in the manuscript preparation	performed phylogenetic studies and the breakpoints distribution statistical analysis, participated in interpretation of results and in the manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5139131	27919246	BM	2	participated in planning the work, interpretation of results and critical discussions	participated in planning the work, interpretation of results and critical discussions	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5139131	27919246	ES	2	designed and performed experimental parts, analyzed and interpreted obtained results and participated in critical discussions	designed and performed experimental parts, analyzed and interpreted obtained results and participated in critical discussions	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5139131	27919246	MP	2	designed and coordinated the work, interpreted and discussed results with all co-authors and wrote the manuscript	designed and coordinated the work, interpreted and discussed results with all co-authors and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Project administration|Writing - Original Draft	YES
5139131	27919246	TVZ	2	designed and performed analyses of sequences deposited in the genome database, interpreted obtained results and participated in critical discussions	designed and performed analyses of sequences deposited in the genome database, interpreted obtained results and participated in critical discussions	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Software	YES
4401762	25885671	CPK	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401762	25885671	DMA	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401762	25885671	ECR	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401762	25885671	HF	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401762	25885671	HF	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401762	25885671	HY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401762	25885671	HY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401762	25885671	HY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401762	25885671	HY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401762	25885671	JW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401762	25885671	KC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401762	25885671	KWG	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401762	25885671	LLB	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401762	25885671	LS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401762	25885671	TCS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401762	25885671	ZY	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
3686666	23758832	BCNT	2	designed the study|in the manuscript write up	designed the study	Conceived and designed the experiments	Methodology	YES
3686666	23758832	BCNT	2	designed the study|in the manuscript write up	in the manuscript write up	Wrote the paper	Writing - Original Draft	YES
3686666	23758832	ET	2	designed the study|they entered the data	designed the study	Conceived and designed the experiments	Methodology	YES
3686666	23758832	ET	2	designed the study|they entered the data	they entered the data	-	-	NO
3686666	23758832	HAJ	2	did the manuscript proof-reading and editing	did the manuscript proof-reading and editing	Wrote the paper	Writing - Review & Editing	YES
3686666	23758832	HNL	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
3686666	23758832	MPH	2	did the manuscript proof-reading and editing	did the manuscript proof-reading and editing	Wrote the paper	Writing - Review & Editing	YES
3686666	23758832	MSD	2	in the manuscript write up|did the manuscript proof-reading and editing	in the manuscript write up	Wrote the paper	Writing - Original Draft	YES
3686666	23758832	MSD	2	in the manuscript write up|did the manuscript proof-reading and editing	did the manuscript proof-reading and editing	Wrote the paper	Writing - Review & Editing	YES
3686666	23758832	SKS	2	did the manuscript proof-reading and editing	did the manuscript proof-reading and editing	Wrote the paper	Writing - Review & Editing	YES
4535308	26288817	A.J.C.	PLoS52	designed research	designed research	Conceived and designed the experiments	Methodology	YES
4535308	26288817	C.G.	PLoS52	performed gene expression profiling in placenta	performed gene expression profiling in placenta	Performed the experiments	Investigation	YES
4535308	26288817	D.C.K.	PLoS52	analyzed data|wrote the paper	analyzed data	Analyzed the data	Formal analysis	YES
4535308	26288817	D.C.K.	PLoS52	analyzed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4535308	26288817	D.J.R.	PLoS52	designed research|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
4535308	26288817	D.J.R.	PLoS52	designed research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4535308	26288817	D.L.F.	PLoS52	designed research|performed gene expression profiling in placenta|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
4535308	26288817	D.L.F.	PLoS52	designed research|performed gene expression profiling in placenta|wrote the paper	performed gene expression profiling in placenta	Performed the experiments	Investigation	YES
4535308	26288817	D.L.F.	PLoS52	designed research|performed gene expression profiling in placenta|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4535308	26288817	E.F.W.	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4535308	26288817	E.L.	PLoS52	designed research	designed research	Conceived and designed the experiments	Methodology	YES
4535308	26288817	E.W.	PLoS52	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
4535308	26288817	M.R.K.	PLoS52	designed research|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
4535308	26288817	M.R.K.	PLoS52	designed research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5491849	28713406	AM	2	planned and performed the experiments	planned and performed the experiments	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5491849	28713406	KT	2	planned and performed the experiments|wrote the manuscript	planned and performed the experiments	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5491849	28713406	KT	2	planned and performed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5491849	28713406	MH	2	planned and performed the experiments	planned and performed the experiments	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5491849	28713406	TSh	2	planned and performed the experiments	planned and performed the experiments	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5491849	28713406	TSu	2	planned and performed the experiments|wrote the manuscript	planned and performed the experiments	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5491849	28713406	TSu	2	planned and performed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5491849	28713406	all authors	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4401763	25885679	ABM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401763	25885679	ABM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401763	25885679	ABM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401763	25885679	ABM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401763	25885679	ABM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401763	25885679	SAM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401763	25885679	SAM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401763	25885679	SAM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401763	25885679	SAM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401763	25885679	SAM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401763	25885679	SR	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401763	25885679	SR	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401763	25885679	SR	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5142174	27923352	EZM	2	performed ssr-pcr and data analysis|assisted in writing and editing the manuscript	performed ssr-pcr and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5142174	27923352	EZM	2	performed ssr-pcr and data analysis|assisted in writing and editing the manuscript	assisted in writing and editing the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5142174	27923352	HG	2	performed sampling, dna extractions, and assisted with data analysis	performed sampling, dna extractions, and assisted with data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5142174	27923352	MK	2	performed sampling, dna extractions, and assisted with data analysis	performed sampling, dna extractions, and assisted with data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5142174	27923352	NC	2	performed sampling, dna extractions, and assisted with data analysis	performed sampling, dna extractions, and assisted with data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5142174	27923352	SK	2	coordinated and organized all research activities, and was responsible for the sequencing and assembly|assisted in writing and editing the manuscript	coordinated and organized all research activities, and was responsible for the sequencing and assembly	Performed the experiments	Investigation|Project administration	YES
5142174	27923352	SK	2	coordinated and organized all research activities, and was responsible for the sequencing and assembly|assisted in writing and editing the manuscript	assisted in writing and editing the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3699368	23805823	AF	2	oversaw the first stages of data analysis of the study and contributed to the drafting of the manuscript	oversaw the first stages of data analysis of the study and contributed to the drafting of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Supervision|Writing - Original Draft	YES
3699368	23805823	AK	2	designed the study, secured funding, oversaw data collection and data analysis, led the analysis of qualitative data, contributed to the drafting of the manuscript and revising it critically for important intellectual content and gave final approval of the version to be submitted	designed the study, secured funding, oversaw data collection and data analysis, led the analysis of qualitative data, contributed to the drafting of the manuscript and revising it critically for important intellectual content and gave final approval of the version to be submitted	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Funding acquisition|Investigation|Methodology|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
3699368	23805823	AM	2	collected data and participated in data analysis for the manuscript	collected data and participated in data analysis for the manuscript	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3699368	23805823	BC	2	collected data and participated in data analysis for the manuscript	collected data and participated in data analysis for the manuscript	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3699368	23805823	BK	2	collected data and participated in data analysis for the manuscript	collected data and participated in data analysis for the manuscript	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3699368	23805823	FA	2	collected data and participated in data analysis for the manuscript	collected data and participated in data analysis for the manuscript	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3699368	23805823	HW	2	assisted in securing funding for the study and overseeing the implementation of it and contributed to the drafting of the manuscript	assisted in securing funding for the study and overseeing the implementation of it and contributed to the drafting of the manuscript	Performed the experiments|Wrote the paper	Funding acquisition|Investigation|Supervision|Writing - Original Draft	YES
3699368	23805823	LP	2	collected data and participated in data analysis for the manuscript	collected data and participated in data analysis for the manuscript	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3699368	23805823	LW	2	collected data and participated in data analysis for the manuscript	collected data and participated in data analysis for the manuscript	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3699368	23805823	MK	2	collected data and participated in data analysis for the manuscript	collected data and participated in data analysis for the manuscript	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3699368	23805823	PMS	2	assisted in securing funding for the study, oversaw the implementation of the study and contributed to the drafting of the manuscript	assisted in securing funding for the study, oversaw the implementation of the study and contributed to the drafting of the manuscript	Performed the experiments|Wrote the paper	Funding acquisition|Investigation|Supervision|Writing - Original Draft	YES
3699368	23805823	PS	2	contributed to the drafting of the manuscript	contributed to the drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
3699368	23805823	RE	2	collected data and participated in data analysis for the manuscript	collected data and participated in data analysis for the manuscript	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3699368	23805823	SN	2	collected data and participated in data analysis for the manuscript	collected data and participated in data analysis for the manuscript	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3699368	23805823	TL	2	assisted in data analysis for this manuscript	assisted in data analysis for this manuscript	Analyzed the data	Formal analysis	YES
3699368	23805823	WYNM	2	led the analysis of quantitative data and drafting of the paper	led the analysis of quantitative data and drafting of the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4563120	26425690	AB	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
4563120	26425690	AJKW	PLoS52	performed the experiments|performed informatics analyses	performed the experiments	Performed the experiments	Investigation	YES
4563120	26425690	AJKW	PLoS52	performed the experiments|performed informatics analyses	performed informatics analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4563120	26425690	CFF	PLoS52	provided clinical material, helped design the study and reviewed the manuscript	provided clinical material, helped design the study and reviewed the manuscript	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Methodology|Resources|Writing - Review & Editing	YES
4563120	26425690	CZ	PLoS52	performed informatics analyses	performed informatics analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4563120	26425690	FHB	PLoS52	provided clinical material, helped design the study and reviewed the manuscript	provided clinical material, helped design the study and reviewed the manuscript	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Methodology|Resources|Writing - Review & Editing	YES
4563120	26425690	LJCP	PLoS52	provided clinical material, helped design the study and reviewed the manuscript	provided clinical material, helped design the study and reviewed the manuscript	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Methodology|Resources|Writing - Review & Editing	YES
4563120	26425690	MJW	PLoS52	performed the experiments|performed informatics analyses	performed the experiments	Performed the experiments	Investigation	YES
4563120	26425690	MJW	PLoS52	performed the experiments|performed informatics analyses	performed informatics analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4563120	26425690	MP	PLoS52	performed the experiments|performed informatics analyses	performed the experiments	Performed the experiments	Investigation	YES
4563120	26425690	MP	PLoS52	performed the experiments|performed informatics analyses	performed informatics analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4563120	26425690	PK	PLoS52	provided clinical material, helped design the study and reviewed the manuscript	provided clinical material, helped design the study and reviewed the manuscript	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Methodology|Resources|Writing - Review & Editing	YES
3419426	22919349	Benito Campos	2	contributed equally to the work	contributed equally to the work	-	-	NO
3419426	22919349	Christine Dictus	2	contributed equally to the work	contributed equally to the work	-	-	NO
3419426	22919349	Rebecca Schule	2	contributed equally to the work	contributed equally to the work	-	-	NO
3700831	23758814	AC	2	supervised the study, analyzed and interpreted the data, and reviewed the manuscript	supervised the study, analyzed and interpreted the data, and reviewed the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Supervision|Writing - Review & Editing	YES
3700831	23758814	AH	2	participated in data collection	participated in data collection	Performed the experiments	Investigation	YES
3700831	23758814	CT	2	participated in study conception and design, data analysis and interpretation, study supervision, and manuscript review	participated in study conception and design, data analysis and interpretation, study supervision, and manuscript review	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Supervision|Writing - Review & Editing	YES
3700831	23758814	MS	2	participated in data collection, analysis and interpretations	participated in data collection, analysis and interpretations	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3700831	23758814	OA-M	2	participated in study conception and design, data collection, analysis and interpretation as well as manuscript drafting	participated in study conception and design, data collection, analysis and interpretation as well as manuscript drafting	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
3700831	23758814	YW	2	participated in study conception and design	participated in study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401764	25884496	BF	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401764	25884496	BF	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4401764	25884496	BF	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401764	25884496	MAR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401764	25884496	MAR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401764	25884496	MAR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401764	25884496	MAR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401764	25884496	MAR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401764	25884496	SC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401764	25884496	SC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401764	25884496	SC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5142292	27908274	CS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5142292	27908274	KK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5142292	27908274	KK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
5142292	27908274	KK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5142292	27908274	MB	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5142292	27908274	MN	PLoS5	Conceived and designed the experiments|Wrote the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5142292	27908274	MN	PLoS5	Conceived and designed the experiments|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5142292	27908274	MWN	PLoS5	Performed the experiments|Analyzed the data|Wrote the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
5142292	27908274	MWN	PLoS5	Performed the experiments|Analyzed the data|Wrote the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
5142292	27908274	MWN	PLoS5	Performed the experiments|Analyzed the data|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5142292	27908274	PM	PLoS5	Analyzed the data|Wrote the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
5142292	27908274	PM	PLoS5	Analyzed the data|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5142292	27908274	TK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5142292	27908274	TP	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4614012	26508906	All authors	2	wrote the paper equally	wrote the paper equally	Wrote the paper	Writing - Original Draft	YES
5491850	28713404	K-HJ	2	design overall experimental schemes|wrote manuscript	design overall experimental schemes	Conceived and designed the experiments	Methodology	YES
5491850	28713404	K-HJ	2	design overall experimental schemes|wrote manuscript	wrote manuscript	Wrote the paper	Writing - Original Draft	YES
5491850	28713404	MK	2	design overall experimental schemes|performed experiments|wrote manuscript	design overall experimental schemes	Conceived and designed the experiments	Methodology	YES
5491850	28713404	MK	2	design overall experimental schemes|performed experiments|wrote manuscript	performed experiments	Performed the experiments	Investigation	YES
5491850	28713404	MK	2	design overall experimental schemes|performed experiments|wrote manuscript	wrote manuscript	Wrote the paper	Writing - Original Draft	YES
5491850	28713404	S-RK	2	design overall experimental schemes	design overall experimental schemes	Conceived and designed the experiments	Methodology	YES
5491850	28713404	Y-SG	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
4452219	26090394	Elmar W. Kuhn	2	contributed equally to this work	contributed equally to this work	-	-	NO
4452219	26090394	Yeong-Hoon Choi	2	contributed equally to this work	contributed equally to this work	-	-	NO
4563121	26425704	AS	4	laboratory data acquisition by	laboratory data acquisition by	Performed the experiments	Investigation	YES
4563121	26425704	HM	4	data analysis and interpretation by	data analysis and interpretation by	Analyzed the data	Formal analysis	YES
4563121	26425704	HT	4	laboratory data acquisition by|data analysis and interpretation by|manuscript drafting by	laboratory data acquisition by	Performed the experiments	Investigation	YES
4563121	26425704	HT	4	laboratory data acquisition by|data analysis and interpretation by|manuscript drafting by	data analysis and interpretation by	Analyzed the data	Formal analysis	YES
4563121	26425704	HT	4	laboratory data acquisition by|data analysis and interpretation by|manuscript drafting by	manuscript drafting by	Wrote the paper	Writing - Original Draft	YES
4563121	26425704	KA	4	laboratory data acquisition by|data analysis and interpretation by|manuscript drafting by	laboratory data acquisition by	Performed the experiments	Investigation	YES
4563121	26425704	KA	4	laboratory data acquisition by|data analysis and interpretation by|manuscript drafting by	data analysis and interpretation by	Analyzed the data	Formal analysis	YES
4563121	26425704	KA	4	laboratory data acquisition by|data analysis and interpretation by|manuscript drafting by	manuscript drafting by	Wrote the paper	Writing - Original Draft	YES
4563121	26425704	MM	4	data analysis and interpretation by|study supervision by	data analysis and interpretation by	Analyzed the data	Formal analysis	YES
4563121	26425704	MM	4	data analysis and interpretation by|study supervision by	study supervision by	-	Supervision	YES
4563121	26425704	NH	4	Study concept and design by|clinical data acquisition by|data analysis and interpretation by|manuscript drafting by	Study concept and design by	Conceived and designed the experiments	Conceptualization|Methodology	YES
4563121	26425704	NH	4	Study concept and design by|clinical data acquisition by|data analysis and interpretation by|manuscript drafting by	clinical data acquisition by	Performed the experiments	Investigation	YES
4563121	26425704	NH	4	Study concept and design by|clinical data acquisition by|data analysis and interpretation by|manuscript drafting by	data analysis and interpretation by	Analyzed the data	Formal analysis	YES
4563121	26425704	NH	4	Study concept and design by|clinical data acquisition by|data analysis and interpretation by|manuscript drafting by	manuscript drafting by	Wrote the paper	Writing - Original Draft	YES
4563121	26425704	SA	4	clinical data acquisition by	clinical data acquisition by	Performed the experiments	Investigation	YES
4563121	26425704	TH	4	laboratory data acquisition by	laboratory data acquisition by	Performed the experiments	Investigation	YES
4563121	26425704	TN	4	Study concept and design by|clinical data acquisition by|laboratory data acquisition by|data analysis and interpretation by|manuscript drafting by	Study concept and design by	Conceived and designed the experiments	Conceptualization|Methodology	YES
4563121	26425704	TN	4	Study concept and design by|clinical data acquisition by|laboratory data acquisition by|data analysis and interpretation by|manuscript drafting by	clinical data acquisition by	Performed the experiments	Investigation	YES
4563121	26425704	TN	4	Study concept and design by|clinical data acquisition by|laboratory data acquisition by|data analysis and interpretation by|manuscript drafting by	laboratory data acquisition by	Performed the experiments	Investigation	YES
4563121	26425704	TN	4	Study concept and design by|clinical data acquisition by|laboratory data acquisition by|data analysis and interpretation by|manuscript drafting by	data analysis and interpretation by	Analyzed the data	Formal analysis	YES
4563121	26425704	TN	4	Study concept and design by|clinical data acquisition by|laboratory data acquisition by|data analysis and interpretation by|manuscript drafting by	manuscript drafting by	Wrote the paper	Writing - Original Draft	YES
4563121	26425704	TT	4	Study concept and design by|data analysis and interpretation by	Study concept and design by	Conceived and designed the experiments	Conceptualization|Methodology	YES
4563121	26425704	TT	4	Study concept and design by|data analysis and interpretation by	data analysis and interpretation by	Analyzed the data	Formal analysis	YES
4563121	26425704	all authors	4	critical revision of the manuscript for important intellectual content by	critical revision of the manuscript for important intellectual content by	Wrote the paper	Writing - Review & Editing	YES
3716897	23849301	EM	2	participated in the conception and design of the study, data collection, results interpretation, and revision of the manuscript	participated in the conception and design of the study, data collection, results interpretation, and revision of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Review & Editing	YES
3716897	23849301	EP	2	participated in review of statistical methods, results interpretation, and revision of the manuscript	participated in review of statistical methods, results interpretation, and revision of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
3716897	23849301	JB	2	participated in review of statistical methods, results interpretation, and revision of the manuscript	participated in review of statistical methods, results interpretation, and revision of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
3716897	23849301	JBN	2	participated in results interpretation and revision of the manuscript	participated in results interpretation and revision of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
3716897	23849301	LT	2	participated in the conception and design of the study, results interpretation, and revision of the manuscript	participated in the conception and design of the study, results interpretation, and revision of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Review & Editing	YES
3716897	23849301	PJD	2	participated in results interpretation and revision of the manuscript	participated in results interpretation and revision of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
3716897	23849301	RC	2	participated in the conception and design of the study, data cleaning and analysis, results interpretation, and drafting and revision of the manuscript	participated in the conception and design of the study, data cleaning and analysis, results interpretation, and drafting and revision of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Data curation|Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
3716897	23849301	TASO	2	clinics and review of drafts	clinics and review of drafts	Wrote the paper	Writing - Original Draft	YES
4401765	25885811	SA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401765	25885811	SA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401765	25885811	SA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401765	25885811	SA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401765	25885811	SA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401765	25885811	YF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401765	25885811	YF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401765	25885811	YF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401765	25885811	YF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401765	25885811	YTC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5142323	27927181	AYL	2	prepared the cotton	prepared the cotton	-	-	NO
5142323	27927181	CSZ	2	provided the rna seq data	provided the rna seq data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5142323	27927181	DJW	2	helped to draft the manuscript	helped to draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5142323	27927181	HHS	2	designed the experiments|provided the rna seq data	designed the experiments	Conceived and designed the experiments	Methodology	YES
5142323	27927181	HHS	2	designed the experiments|provided the rna seq data	provided the rna seq data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5142323	27927181	JC	2	participated in the sequence alignment and pmes activity test	participated in the sequence alignment and pmes activity test	Performed the experiments	Investigation	YES
5142323	27927181	JWG	2	prepared the cotton	prepared the cotton	-	-	NO
5142323	27927181	JWL	2	helped to draft the manuscript	helped to draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5142323	27927181	MJ	2	performed phylogenetic analyses of pmes	performed phylogenetic analyses of pmes	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5142323	27927181	PKK	2	performed phylogenetic analyses of pmes	performed phylogenetic analyses of pmes	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5142323	27927181	PTL	2	performed phylogenetic analyses of pmes	performed phylogenetic analyses of pmes	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5142323	27927181	QG	2	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5142323	27927181	QWL	2	performed phylogenetic analyses of pmes	performed phylogenetic analyses of pmes	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5142323	27927181	SMF	2	participated in the sequence alignment and pmes activity test	participated in the sequence alignment and pmes activity test	Performed the experiments	Investigation	YES
5142323	27927181	TTC	2	helped to draft the manuscript	helped to draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5142323	27927181	WJL	2	conducted gene expression analyses and drafted the manuscript	conducted gene expression analyses and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5142323	27927181	WKG	2	helped to draft the manuscript	helped to draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5142323	27927181	WWS	2	performed phylogenetic analyses of pmes	performed phylogenetic analyses of pmes	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5142323	27927181	XYD	2	performed phylogenetic analyses of pmes	performed phylogenetic analyses of pmes	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5142323	27927181	YLY	2	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5142323	27927181	YNT	2	performed phylogenetic analyses of pmes	performed phylogenetic analyses of pmes	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5142323	27927181	YZS	2	helped to draft the manuscript	helped to draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5142323	27927181	ZZ	2	performed phylogenetic analyses of pmes	performed phylogenetic analyses of pmes	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4563141	26425692	AK	2	performed data collection and analysis|interpreted the data	performed data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4563141	26425692	AK	2	performed data collection and analysis|interpreted the data	interpreted the data	Analyzed the data	Formal analysis	YES
4563141	26425692	BK	2	performed data collection and analysis	performed data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4563141	26425692	HD	2	designed the study|performed data collection and analysis|interpreted the data	designed the study	Conceived and designed the experiments	Methodology	YES
4563141	26425692	HD	2	designed the study|performed data collection and analysis|interpreted the data	performed data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4563141	26425692	HD	2	designed the study|performed data collection and analysis|interpreted the data	interpreted the data	Analyzed the data	Formal analysis	YES
4563141	26425692	MM	2	designed the study|performed data collection and analysis|interpreted the data|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
4563141	26425692	MM	2	designed the study|performed data collection and analysis|interpreted the data|wrote the manuscript	performed data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4563141	26425692	MM	2	designed the study|performed data collection and analysis|interpreted the data|wrote the manuscript	interpreted the data	Analyzed the data	Formal analysis	YES
4563141	26425692	MM	2	designed the study|performed data collection and analysis|interpreted the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4563141	26425692	NG	2	designed the study|performed data collection and analysis|interpreted the data|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
4563141	26425692	NG	2	designed the study|performed data collection and analysis|interpreted the data|wrote the manuscript	performed data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4563141	26425692	NG	2	designed the study|performed data collection and analysis|interpreted the data|wrote the manuscript	interpreted the data	Analyzed the data	Formal analysis	YES
4563141	26425692	NG	2	designed the study|performed data collection and analysis|interpreted the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4563141	26425692	PK	2	designed the study|performed data collection and analysis|interpreted the data|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
4563141	26425692	PK	2	designed the study|performed data collection and analysis|interpreted the data|wrote the manuscript	performed data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4563141	26425692	PK	2	designed the study|performed data collection and analysis|interpreted the data|wrote the manuscript	interpreted the data	Analyzed the data	Formal analysis	YES
4563141	26425692	PK	2	designed the study|performed data collection and analysis|interpreted the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3718701	23842109	AA	2	participated in counseling the study participants, filling study questionnaires and sample collection	participated in counseling the study participants, filling study questionnaires and sample collection	Performed the experiments	Investigation	YES
3718701	23842109	DK	2	was a lead author on planning, implementation of the study, data analysis, and writing of the draft, interim and final version of the manuscript	was a lead author on planning, implementation of the study, data analysis, and writing of the draft, interim and final version of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
3718701	23842109	GG	2	participated in different laboratory tests	participated in different laboratory tests	Performed the experiments	Investigation	YES
3718701	23842109	YA	2	participated in different laboratory tests	participated in different laboratory tests	Performed the experiments	Investigation	YES
5491852	28713395	AH	2	made the data analysis|wrote and edited the text	made the data analysis	Analyzed the data	Formal analysis	YES
5491852	28713395	AH	2	made the data analysis|wrote and edited the text	wrote and edited the text	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5491852	28713395	CA	2	made the film trials and assisted with the plot trials	made the film trials and assisted with the plot trials	-	-	NO
5491852	28713395	CN	2	made the large scale plot measurements	made the large scale plot measurements	Performed the experiments	Investigation	YES
5491852	28713395	DS	2	produced the miscanthus seed	produced the miscanthus seed	-	-	NO
5491852	28713395	GS	2	produced the miscanthus seed	produced the miscanthus seed	-	-	NO
5491852	28713395	HS	2	made the large scale plot measurements	made the large scale plot measurements	Performed the experiments	Investigation	YES
5491852	28713395	JC-B	2	wrote and edited the text|conceived the study	wrote and edited the text	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5491852	28713395	JC-B	2	wrote and edited the text|conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5491852	28713395	JM	2	wrote and edited the text|made the commercial-scale trial measurements and established the plots	wrote and edited the text	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5491852	28713395	JM	2	wrote and edited the text|made the commercial-scale trial measurements and established the plots	made the commercial-scale trial measurements and established the plots	Performed the experiments	Investigation	YES
5491852	28713395	JY	2	constructed the economic model	constructed the economic model	Performed the experiments	Investigation|Methodology	YES
5491852	28713395	KS	2	conducted the in vitro cloning and clone selection	conducted the in vitro cloning and clone selection	Performed the experiments	Investigation	YES
5491852	28713395	MM	2	wrote and edited the text|made the commercial-scale trial measurements and established the plots	wrote and edited the text	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5491852	28713395	MM	2	wrote and edited the text|made the commercial-scale trial measurements and established the plots	made the commercial-scale trial measurements and established the plots	Performed the experiments	Investigation	YES
5491852	28713395	MW	2	made the large scale plot measurements	made the large scale plot measurements	Performed the experiments	Investigation	YES
5491852	28713395	RS	2	wrote and edited the text|conducted the elite seed trials|produced the miscanthus seed	wrote and edited the text	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5491852	28713395	RS	2	wrote and edited the text|conducted the elite seed trials|produced the miscanthus seed	conducted the elite seed trials	Performed the experiments	Investigation	YES
5491852	28713395	RS	2	wrote and edited the text|conducted the elite seed trials|produced the miscanthus seed	produced the miscanthus seed	-	-	NO
5491852	28713395	SC	2	produced the miscanthus seed	produced the miscanthus seed	-	-	NO
3092491	21566737	All authors	2	have read and approved the final manuscript	have read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
3092491	21566737	CS	2	participated in collection of data, data analysis and revision of the manuscript|participated in collection of data, data analysis and revision of the manuscript	participated in collection of data, data analysis and revision of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
3092491	21566737	CS	2	participated in collection of data, data analysis and revision of the manuscript|participated in collection of data, data analysis and revision of the manuscript	participated in collection of data, data analysis and revision of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
3092491	21566737	FM	2	participated in the design of the study, collection of data, and drafting the manuscript|participated in the design of the study, collection of data, and drafting the manuscript	participated in the design of the study, collection of data, and drafting the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
3092491	21566737	FM	2	participated in the design of the study, collection of data, and drafting the manuscript|participated in the design of the study, collection of data, and drafting the manuscript	participated in the design of the study, collection of data, and drafting the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
3092491	21566737	RKN	2	conceived and participated in the design of the study and revision of the manuscript|conceived and participated in the design of the study and revision of the manuscript	conceived and participated in the design of the study and revision of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
3092491	21566737	RKN	2	conceived and participated in the design of the study and revision of the manuscript|conceived and participated in the design of the study and revision of the manuscript	conceived and participated in the design of the study and revision of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
4401767	25884625	BS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401767	25884625	BS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401767	25884625	BS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401767	25884625	BS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401767	25884625	BS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401767	25884625	MC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4401767	25884625	MC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401767	25884625	OS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401767	25884625	OS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4401767	25884625	OS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401767	25884625	ST	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
3727961	23885958	AA	2	designed and conducted the study, interpreted the data, and prepared and edited the manuscript	designed and conducted the study, interpreted the data, and prepared and edited the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
3727961	23885958	JA	2	designed and conducted the study, interpreted the data, and prepared and edited the manuscript	designed and conducted the study, interpreted the data, and prepared and edited the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
3727961	23885958	NH	2	designed and conducted the study, interpreted the data, and prepared and edited the manuscript	designed and conducted the study, interpreted the data, and prepared and edited the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
3727961	23885958	PT	2	designed and conducted the study, interpreted the data, and prepared and edited the manuscript	designed and conducted the study, interpreted the data, and prepared and edited the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
3727961	23885958	SP	2	designed and conducted the study, interpreted the data, and prepared and edited the manuscript	designed and conducted the study, interpreted the data, and prepared and edited the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
3727961	23885958	TC	2	designed and conducted the study, interpreted the data, and prepared and edited the manuscript	designed and conducted the study, interpreted the data, and prepared and edited the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
4452233	26090389	Bo Liu	2	contributed equally to this work	contributed equally to this work	-	-	NO
4452233	26090389	Rolando A. Rebolledo	2	contributed equally to this work	contributed equally to this work	-	-	NO
4268480	25568777	AES	2	were responsible for study conception, design and acquisition of data|were responsible for analysis and interpretation of data	were responsible for study conception, design and acquisition of data	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
4268480	25568777	AES	2	were responsible for study conception, design and acquisition of data|were responsible for analysis and interpretation of data	were responsible for analysis and interpretation of data	Analyzed the data	Formal analysis	YES
4268480	25568777	All authors	2	were responsible for final approval of the version to be published	were responsible for final approval of the version to be published	-	-	NO
4268480	25568777	IAH	2	were responsible for study conception, design and acquisition of data|were responsible for drafting the article	were responsible for study conception, design and acquisition of data	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
4268480	25568777	IAH	2	were responsible for study conception, design and acquisition of data|were responsible for drafting the article	were responsible for drafting the article	Wrote the paper	Writing - Original Draft	YES
4268480	25568777	MJA	2	were responsible for study conception, design and acquisition of data	were responsible for study conception, design and acquisition of data	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
4268480	25568777	RKP	2	were responsible for study conception, design and acquisition of data|were responsible for analysis and interpretation of data|were responsible for drafting the article	were responsible for study conception, design and acquisition of data	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
4268480	25568777	RKP	2	were responsible for study conception, design and acquisition of data|were responsible for analysis and interpretation of data|were responsible for drafting the article	were responsible for analysis and interpretation of data	Analyzed the data	Formal analysis	YES
4268480	25568777	RKP	2	were responsible for study conception, design and acquisition of data|were responsible for analysis and interpretation of data|were responsible for drafting the article	were responsible for drafting the article	Wrote the paper	Writing - Original Draft	YES
4587998	26501106	B.A.R.	2	analyzed the data and prepared the figures and tables|wrote the manuscript	analyzed the data and prepared the figures and tables	Analyzed the data	Formal analysis|Visualization	YES
4587998	26501106	B.A.R.	2	analyzed the data and prepared the figures and tables|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4587998	26501106	D.P.J.	2	jointly conceived, designed and supervised the research|performed the experiments and provided the material|wrote the manuscript	jointly conceived, designed and supervised the research	Conceived and designed the experiments	Conceptualization|Methodology|Supervision	YES
4587998	26501106	D.P.J.	2	jointly conceived, designed and supervised the research|performed the experiments and provided the material|wrote the manuscript	performed the experiments and provided the material	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4587998	26501106	D.P.J.	2	jointly conceived, designed and supervised the research|performed the experiments and provided the material|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4587998	26501106	M.M.	2	jointly conceived, designed and supervised the research|wrote the manuscript	jointly conceived, designed and supervised the research	Conceived and designed the experiments	Conceptualization|Methodology|Supervision	YES
4587998	26501106	M.M.	2	jointly conceived, designed and supervised the research|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4587998	26501106	Q.W.	2	analyzed the data and prepared the figures and tables|wrote the manuscript	analyzed the data and prepared the figures and tables	Analyzed the data	Formal analysis|Visualization	YES
4587998	26501106	Q.W.	2	analyzed the data and prepared the figures and tables|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3765690	23870285	CM	2	contributed to conception and design, drafting and critical revision of the article|undertook acquisition, analysis and interpretation of data	contributed to conception and design, drafting and critical revision of the article	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
3765690	23870285	CM	2	contributed to conception and design, drafting and critical revision of the article|undertook acquisition, analysis and interpretation of data	undertook acquisition, analysis and interpretation of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3765690	23870285	JM	2	contributed to conception and design, drafting and critical revision of the article|undertook acquisition, analysis and interpretation of data	contributed to conception and design, drafting and critical revision of the article	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
3765690	23870285	JM	2	contributed to conception and design, drafting and critical revision of the article|undertook acquisition, analysis and interpretation of data	undertook acquisition, analysis and interpretation of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3765690	23870285	MLN	2	contributed to conception and design, drafting and critical revision of the article	contributed to conception and design, drafting and critical revision of the article	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
3765690	23870285	RE	2	contributed to conception and design, drafting and critical revision of the article	contributed to conception and design, drafting and critical revision of the article	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
3765690	23870285	RL	2	contributed to conception and design, drafting and critical revision of the article|undertook acquisition, analysis and interpretation of data	contributed to conception and design, drafting and critical revision of the article	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
3765690	23870285	RL	2	contributed to conception and design, drafting and critical revision of the article|undertook acquisition, analysis and interpretation of data	undertook acquisition, analysis and interpretation of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5142383	27927184	CM	2	helped with experimental design, supervised experiments, and edited the final version of the manuscript	helped with experimental design, supervised experiments, and edited the final version of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Supervision|Writing - Review & Editing	YES
5142383	27927184	LGG	2	designed and conducted the experiments, performed all analyses and wrote the manuscript	designed and conducted the experiments, performed all analyses and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5142383	27927184	MAG	2	helped with experimental design, supervised research and edited the final version of the manuscript	helped with experimental design, supervised research and edited the final version of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Supervision|Writing - Review & Editing	YES
5142383	27927184	MKD	2	supervised the research and edited the final version of the manuscript	supervised the research and edited the final version of the manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
5684858	28805973	All authors	1	Wrote and contributed to the writing of the manuscript	Wrote and contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5491900	28713403	C-CP	PLoS52	conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5491900	28713403	JL	PLoS52	conceived the study|analyzed the data|wrote the initial manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5491900	28713403	JL	PLoS52	conceived the study|analyzed the data|wrote the initial manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5491900	28713403	JL	PLoS52	conceived the study|analyzed the data|wrote the initial manuscript	wrote the initial manuscript	Wrote the paper	Writing - Original Draft	YES
5491900	28713403	RS	PLoS52	conceived the study|wrote the initial manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5491900	28713403	RS	PLoS52	conceived the study|wrote the initial manuscript	wrote the initial manuscript	Wrote the paper	Writing - Original Draft	YES
5491900	28713403	XG	PLoS52	conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5491900	28713403	all authors	PLoS52	reviewed and edited the final submission	reviewed and edited the final submission	Wrote the paper	Writing - Review & Editing	YES
4401770	25885861	JK	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401770	25885861	JK	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401770	25885861	JK	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401770	25885861	MT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401770	25885861	MT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401770	25885861	MT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401770	25885861	MT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401770	25885861	NE	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401770	25885861	NE	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401770	25885861	WW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401770	25885861	WW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401770	25885861	WW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3766273	24004690	AL	2	contribuited to the care of the patient	contribuited to the care of the patient	Performed the experiments	Investigation	YES
3766273	24004690	BC	2	contribuited to the care of the patient	contribuited to the care of the patient	Performed the experiments	Investigation	YES
3766273	24004690	DF	2	to laboratory analyses|made a substantial contribution to draft the manuscript and revised the draft	to laboratory analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3766273	24004690	DF	2	to laboratory analyses|made a substantial contribution to draft the manuscript and revised the draft	made a substantial contribution to draft the manuscript and revised the draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3766273	24004690	FF	2	contribuited to the care of the patient|drew up the first draft of the report	contribuited to the care of the patient	Performed the experiments	Investigation	YES
3766273	24004690	FF	2	contribuited to the care of the patient|drew up the first draft of the report	drew up the first draft of the report	Wrote the paper	Writing - Original Draft	YES
3766273	24004690	GB	2	to laboratory analyses	to laboratory analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3766273	24004690	MG	2	contribuited to the care of the patient	contribuited to the care of the patient	Performed the experiments	Investigation	YES
3766273	24004690	MT	2	to laboratory analyses	to laboratory analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3766273	24004690	PC	2	contribuited to the care of the patient|made a substantial contribution to draft the manuscript and revised the draft	contribuited to the care of the patient	Performed the experiments	Investigation	YES
3766273	24004690	PC	2	contribuited to the care of the patient|made a substantial contribution to draft the manuscript and revised the draft	made a substantial contribution to draft the manuscript and revised the draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3766273	24004690	SG	2	to neuroradiologic examination	to neuroradiologic examination	Performed the experiments	Investigation	YES
3425807	22927782	A. Isogawa	2	are outpatient clinic doctors who contributed to this study	are outpatient clinic doctors who contributed to this study	-	-	NO
3425807	22927782	H. Yoshida	2	is also the final corresponding author	is also the final corresponding author	-	-	NO
3425807	22927782	K. Tagawa	2	are outpatient clinic doctors who contributed to this study	are outpatient clinic doctors who contributed to this study	-	-	NO
3425807	22927782	M. Iwamoto	2	are outpatient clinic doctors who contributed to this study	are outpatient clinic doctors who contributed to this study	-	-	NO
3425807	22927782	M. Ohsugi	2	are outpatient clinic doctors who contributed to this study	are outpatient clinic doctors who contributed to this study	-	-	NO
3425807	22927782	M. Toda	2	are outpatient clinic doctors who contributed to this study	are outpatient clinic doctors who contributed to this study	-	-	NO
5492020	28713417	AG	1	Conceived and designed the experiments, contributed to the writing and revision of the manuscript|Performed the experiments and analyzed the results	Conceived and designed the experiments, contributed to the writing and revision of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5492020	28713417	AG	1	Conceived and designed the experiments, contributed to the writing and revision of the manuscript|Performed the experiments and analyzed the results	Performed the experiments and analyzed the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5492020	28713417	IK	1	Conceived and designed the experiments, contributed to the writing and revision of the manuscript	Conceived and designed the experiments, contributed to the writing and revision of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5492020	28713417	SM	1	Conceived and designed the experiments, contributed to the writing and revision of the manuscript	Conceived and designed the experiments, contributed to the writing and revision of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5492020	28713417	WS	1	Conceived and designed the experiments, contributed to the writing and revision of the manuscript|Performed the experiments and analyzed the results	Conceived and designed the experiments, contributed to the writing and revision of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5492020	28713417	WS	1	Conceived and designed the experiments, contributed to the writing and revision of the manuscript|Performed the experiments and analyzed the results	Performed the experiments and analyzed the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4401771	25885573	FR	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401771	25885573	FR	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401771	25885573	JLB	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401771	25885573	MD	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401771	25885573	MF	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401771	25885573	RC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401771	25885573	RC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401771	25885573	RC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5492162	28713405	GC	2	supervised to the preparation of the manuscript and gave a substantial contribution in improving the different parts	supervised to the preparation of the manuscript and gave a substantial contribution in improving the different parts	Wrote the paper	Supervision|Writing - Original Draft	YES
5492162	28713405	MC	2	improved the manuscript and especially the physiological part	improved the manuscript and especially the physiological part	Wrote the paper	Writing - Review & Editing	YES
5492162	28713405	PK	2	wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
4588396	26501111	ADL	2	conducted experimental work|were responsible for patient recruitment and sample collection|were responsible for clinical follow-up|contributed to study design|wrote the manuscript	conducted experimental work	Performed the experiments	Investigation	YES
4588396	26501111	ADL	2	conducted experimental work|were responsible for patient recruitment and sample collection|were responsible for clinical follow-up|contributed to study design|wrote the manuscript	were responsible for patient recruitment and sample collection	Performed the experiments	Investigation	YES
4588396	26501111	ADL	2	conducted experimental work|were responsible for patient recruitment and sample collection|were responsible for clinical follow-up|contributed to study design|wrote the manuscript	were responsible for clinical follow-up	-	-	NO
4588396	26501111	ADL	2	conducted experimental work|were responsible for patient recruitment and sample collection|were responsible for clinical follow-up|contributed to study design|wrote the manuscript	contributed to study design	Conceived and designed the experiments	Methodology	YES
4588396	26501111	ADL	2	conducted experimental work|were responsible for patient recruitment and sample collection|were responsible for clinical follow-up|contributed to study design|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4588396	26501111	AGL	2	performed analyses	performed analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4588396	26501111	ARM	2	conducted experimental work	conducted experimental work	Performed the experiments	Investigation	YES
4588396	26501111	AYW	2	performed histopathology	performed histopathology	Performed the experiments	Investigation	YES
4588396	26501111	CMM	2	performed analyses	performed analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4588396	26501111	CSC	2	were responsible for patient recruitment and sample collection	were responsible for patient recruitment and sample collection	Performed the experiments	Investigation	YES
4588396	26501111	DEN	2	were responsible for patient recruitment and sample collection|contributed to study design	were responsible for patient recruitment and sample collection	Performed the experiments	Investigation	YES
4588396	26501111	DEN	2	were responsible for patient recruitment and sample collection|contributed to study design	contributed to study design	Conceived and designed the experiments	Methodology	YES
4588396	26501111	HG	2	were responsible for patient recruitment and sample collection|contributed to study design	were responsible for patient recruitment and sample collection	Performed the experiments	Investigation	YES
4588396	26501111	HG	2	were responsible for patient recruitment and sample collection|contributed to study design	contributed to study design	Conceived and designed the experiments	Methodology	YES
4588396	26501111	HRA	2	conducted experimental work|were responsible for clinical follow-up|contributed to study design|performed analyses|wrote the manuscript	conducted experimental work	Performed the experiments	Investigation	YES
4588396	26501111	HRA	2	conducted experimental work|were responsible for clinical follow-up|contributed to study design|performed analyses|wrote the manuscript	were responsible for clinical follow-up	-	-	NO
4588396	26501111	HRA	2	conducted experimental work|were responsible for clinical follow-up|contributed to study design|performed analyses|wrote the manuscript	contributed to study design	Conceived and designed the experiments	Methodology	YES
4588396	26501111	HRA	2	conducted experimental work|were responsible for clinical follow-up|contributed to study design|performed analyses|wrote the manuscript	performed analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4588396	26501111	HRA	2	conducted experimental work|were responsible for clinical follow-up|contributed to study design|performed analyses|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4588396	26501111	HW	2	conducted experimental work	conducted experimental work	Performed the experiments	Investigation	YES
4588396	26501111	IGM	2	contributed to study design	contributed to study design	Conceived and designed the experiments	Methodology	YES
4588396	26501111	JC	2	conducted experimental work|performed histopathology	conducted experimental work	Performed the experiments	Investigation	YES
4588396	26501111	JC	2	conducted experimental work|performed histopathology	performed histopathology	Performed the experiments	Investigation	YES
4588396	26501111	JK	2	conducted experimental work	conducted experimental work	Performed the experiments	Investigation	YES
4588396	26501111	JL	2	were responsible for clinical follow-up	were responsible for clinical follow-up	-	-	NO
4588396	26501111	LAE	2	performed histopathology	performed histopathology	Performed the experiments	Investigation	YES
4588396	26501111	MJD	2	performed analyses|wrote the manuscript	performed analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4588396	26501111	MJD	2	performed analyses|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4588396	26501111	NCS	2	were responsible for patient recruitment and sample collection	were responsible for patient recruitment and sample collection	Performed the experiments	Investigation	YES
4588396	26501111	NLS	2	were responsible for patient recruitment and sample collection|were responsible for clinical follow-up	were responsible for patient recruitment and sample collection	Performed the experiments	Investigation	YES
4588396	26501111	NLS	2	were responsible for patient recruitment and sample collection|were responsible for clinical follow-up	were responsible for clinical follow-up	-	-	NO
4588396	26501111	RH	2	conducted experimental work	conducted experimental work	Performed the experiments	Investigation	YES
4588396	26501111	RR	2	performed analyses	performed analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4588396	26501111	RS	2	performed analyses|wrote the manuscript	performed analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4588396	26501111	RS	2	performed analyses|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4588396	26501111	SH	2	performed analyses	performed analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4588396	26501111	SLV	2	performed analyses	performed analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4588396	26501111	VG	2	were responsible for patient recruitment and sample collection	were responsible for patient recruitment and sample collection	Performed the experiments	Investigation	YES
4284439	25568793	CE	2	analyzed and interpreted the patient data regarding post-surgical outcome	analyzed and interpreted the patient data regarding post-surgical outcome	Analyzed the data	Formal analysis	YES
4284439	25568793	FD	2	performed the surgical procedures and were major contributors in writing the manuscript	performed the surgical procedures and were major contributors in writing the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4284439	25568793	FP	2	analyzed and interpreted the patient data regarding post-surgical outcome	analyzed and interpreted the patient data regarding post-surgical outcome	Analyzed the data	Formal analysis	YES
4284439	25568793	MW	2	performed the surgical procedures and were major contributors in writing the manuscript	performed the surgical procedures and were major contributors in writing the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3827884	24199645	AKN	2	helped in drafting and critically revising the manuscript	helped in drafting and critically revising the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3827884	24199645	EB	2	designed the study, collected samples, analysed them and drafted the manuscript	designed the study, collected samples, analysed them and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
3827884	24199645	MMG	2	helped in data analysis and interpretation and reviewed the manuscript	helped in data analysis and interpretation and reviewed the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
3827884	24199645	RL	2	helped in critically reviewing the manuscript	helped in critically reviewing the manuscript	Wrote the paper	Writing - Review & Editing	YES
3827884	24199645	SAK	2	conceptualized the idea, helped in designing experiment, analysis of the samples, interpretation of data and review of the manuscript	conceptualized the idea, helped in designing experiment, analysis of the samples, interpretation of data and review of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Review & Editing	YES
3827884	24199645	VO	2	helped in critical review of the paper	helped in critical review of the paper	Wrote the paper	Writing - Review & Editing	YES
5142436	27927182	BG	2	were responsible for the bioinformatics analysis of the data|wrote the manuscript	were responsible for the bioinformatics analysis of the data	Analyzed the data	Formal analysis	YES
5142436	27927182	BG	2	were responsible for the bioinformatics analysis of the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5142436	27927182	EH	2	conceived the project	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5142436	27927182	GT	2	were responsible for the bioinformatics analysis of the data	were responsible for the bioinformatics analysis of the data	Analyzed the data	Formal analysis	YES
5142436	27927182	MM	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5142436	27927182	NLR	2	conceived the project	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5142436	27927182	PVH	2	conceived the project	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5492192	28713418	DG	7	Contribute in compilation of concepts from individual articles of the research topic, manuscript write up and revision	Contribute in compilation of concepts from individual articles of the research topic, manuscript write up and revision	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
5492192	28713418	HH	7	Provided guidance during manuscript write up and contributed to the revision of the manuscript draft	Provided guidance during manuscript write up and contributed to the revision of the manuscript draft	Wrote the paper	Supervision|Writing - Original Draft|Writing - Review & Editing	YES
5492192	28713418	JX	7	Contributed to the revision of the manuscript write-up	Contributed to the revision of the manuscript write-up	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5492192	28713418	QL	7	Contributed to the revision of the manuscript write-up	Contributed to the revision of the manuscript write-up	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4401772	25886158	BK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401772	25886158	BK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401772	25886158	BK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401772	25886158	BK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401772	25886158	BK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401772	25886158	JD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401772	25886158	JD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401772	25886158	JD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401772	25886158	JD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401772	25886158	JD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3425810	22927780	J. Siegrist	2	revised the statistical analyses and helped to draft the paper	revised the statistical analyses and helped to draft the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
3425810	22927780	N. Magnavita	2	devised the study and collected and processed the data	devised the study and collected and processed the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Data curation|Investigation	YES
3832883	24215971	VM	2	was one of the paediatricians that offered care for the children at the study site	was one of the paediatricians that offered care for the children at the study site	-	-	NO
5684862	28805980	H. Suzuki	2	conducted experiments	conducted experiments	Performed the experiments	Investigation	YES
5684862	28805980	K. Muraki	2	participated in research design|conducted experiments|wrote or contributed to the writing of the manuscript	participated in research design	Conceived and designed the experiments	-	YES
5684862	28805980	K. Muraki	2	participated in research design|conducted experiments|wrote or contributed to the writing of the manuscript	conducted experiments	Performed the experiments	Investigation	YES
5684862	28805980	K. Muraki	2	participated in research design|conducted experiments|wrote or contributed to the writing of the manuscript	wrote or contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5684862	28805980	N. Hatano	2	contributed new reagents or analytic tools	contributed new reagents or analytic tools	Contributed reagents/materials/analysis tools	Resources	YES
5684862	28805980	T. Hirata	2	contributed new reagents or analytic tools	contributed new reagents or analytic tools	Contributed reagents/materials/analysis tools	Resources	YES
5684862	28805980	T. Sekine	2	contributed new reagents or analytic tools|wrote or contributed to the writing of the manuscript	contributed new reagents or analytic tools	Contributed reagents/materials/analysis tools	Resources	YES
5684862	28805980	T. Sekine	2	contributed new reagents or analytic tools|wrote or contributed to the writing of the manuscript	wrote or contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5684862	28805980	Y. Ando	2	conducted experiments	conducted experiments	Performed the experiments	Investigation	YES
5684862	28805980	Y. Muraki	2	conducted experiments	conducted experiments	Performed the experiments	Investigation	YES
4588398	26501104	AP	2	supervised the study	supervised the study	-	Supervision	YES
4588398	26501104	All authors	2	critically reviewed and approved the manuscript	critically reviewed and approved the manuscript	Wrote the paper	Writing - Review & Editing	YES
4588398	26501104	BM	2	performed sanger sequencing	performed sanger sequencing	Performed the experiments	Investigation	YES
4588398	26501104	CL	2	designed the study|analysed and interpreted data|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
4588398	26501104	CL	2	designed the study|analysed and interpreted data|wrote the manuscript	analysed and interpreted data	Analyzed the data	Formal analysis	YES
4588398	26501104	CL	2	designed the study|analysed and interpreted data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4588398	26501104	EHa	2	conducted and supervised exome sequencing and variant calling	conducted and supervised exome sequencing and variant calling	Performed the experiments	Investigation|Supervision	YES
4588398	26501104	EHu	2	contributed patient samples and collected clinical and genetic data	contributed patient samples and collected clinical and genetic data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4588398	26501104	ER	2	contributed patient samples and collected clinical and genetic data	contributed patient samples and collected clinical and genetic data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4588398	26501104	GLC	2	contributed patient samples and collected clinical and genetic data	contributed patient samples and collected clinical and genetic data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4588398	26501104	IES	2	contributed patient samples and collected clinical and genetic data	contributed patient samples and collected clinical and genetic data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4588398	26501104	JHC	2	contributed patient samples and collected clinical and genetic data	contributed patient samples and collected clinical and genetic data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4588398	26501104	JMM	2	contributed patient samples and collected clinical and genetic data	contributed patient samples and collected clinical and genetic data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4588398	26501104	JN	2	contributed patient samples and collected clinical and genetic data	contributed patient samples and collected clinical and genetic data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4588398	26501104	JW	2	contributed patient samples and collected clinical and genetic data	contributed patient samples and collected clinical and genetic data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4588398	26501104	JWS	2	contributed patient samples and collected clinical and genetic data	contributed patient samples and collected clinical and genetic data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4588398	26501104	KH	2	contributed patient samples and collected clinical and genetic data	contributed patient samples and collected clinical and genetic data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4588398	26501104	LGS	2	contributed patient samples and collected clinical and genetic data	contributed patient samples and collected clinical and genetic data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4588398	26501104	LHH	2	performed sanger sequencing	performed sanger sequencing	Performed the experiments	Investigation	YES
4588398	26501104	LN	2	contributed patient samples and collected clinical and genetic data	contributed patient samples and collected clinical and genetic data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4588398	26501104	MIR	2	contributed patient samples and collected clinical and genetic data	contributed patient samples and collected clinical and genetic data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4588398	26501104	MOR	2	contributed patient samples and collected clinical and genetic data	contributed patient samples and collected clinical and genetic data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4588398	26501104	ND	2	contributed patient samples and collected clinical and genetic data	contributed patient samples and collected clinical and genetic data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4588398	26501104	NS	2	contributed patient samples and collected clinical and genetic data	contributed patient samples and collected clinical and genetic data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4588398	26501104	PG	2	conducted and supervised exome sequencing and variant calling	conducted and supervised exome sequencing and variant calling	Performed the experiments	Investigation|Supervision	YES
4588398	26501104	RE	2	contributed patient samples and collected clinical and genetic data	contributed patient samples and collected clinical and genetic data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4588398	26501104	RHT	2	contributed patient samples and collected clinical and genetic data	contributed patient samples and collected clinical and genetic data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4588398	26501104	SB	2	contributed patient samples and collected clinical and genetic data|analysed and interpreted data|wrote the manuscript	contributed patient samples and collected clinical and genetic data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4588398	26501104	SB	2	contributed patient samples and collected clinical and genetic data|analysed and interpreted data|wrote the manuscript	analysed and interpreted data	Analyzed the data	Formal analysis	YES
4588398	26501104	SB	2	contributed patient samples and collected clinical and genetic data|analysed and interpreted data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4588398	26501104	SFB	2	contributed patient samples and collected clinical and genetic data	contributed patient samples and collected clinical and genetic data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4588398	26501104	SKC	2	contributed patient samples and collected clinical and genetic data	contributed patient samples and collected clinical and genetic data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4588398	26501104	SM	2	contributed patient samples and collected clinical and genetic data	contributed patient samples and collected clinical and genetic data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4588398	26501104	SMS	2	designed the study|contributed patient samples and collected clinical and genetic data|supervised the study|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
4588398	26501104	SMS	2	designed the study|contributed patient samples and collected clinical and genetic data|supervised the study|wrote the manuscript	contributed patient samples and collected clinical and genetic data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4588398	26501104	SMS	2	designed the study|contributed patient samples and collected clinical and genetic data|supervised the study|wrote the manuscript	supervised the study	-	Supervision	YES
4588398	26501104	SMS	2	designed the study|contributed patient samples and collected clinical and genetic data|supervised the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4588398	26501104	SMZ	2	contributed patient samples and collected clinical and genetic data	contributed patient samples and collected clinical and genetic data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4588398	26501104	VP	2	conducted and supervised exome sequencing and variant calling	conducted and supervised exome sequencing and variant calling	Performed the experiments	Investigation|Supervision	YES
4588398	26501104	WOP	2	contributed patient samples and collected clinical and genetic data	contributed patient samples and collected clinical and genetic data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4284441	25568797	All authors	2	contributed equally in this case report	contributed equally in this case report	-	-	NO
4401773	25884225	CW	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4401773	25884225	CW	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4401773	25884225	CW	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401773	25884225	DYC	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4401773	25884225	DYC	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4401773	25884225	DYC	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401773	25884225	HW	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401773	25884225	HW	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401773	25884225	HW	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401773	25884225	HW	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401773	25884225	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401773	25884225	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401773	25884225	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401773	25884225	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401773	25884225	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401773	25884225	MHZ	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401773	25884225	TTM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401773	25884225	TTM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401773	25884225	TTM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401773	25884225	TTM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5492466	28713408	D-ZY	PLoS52	conceived and designed the research|edited the manuscript	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5492466	28713408	D-ZY	PLoS52	conceived and designed the research|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5492466	28713408	F-SZ	PLoS52	conceived and designed the research|contributed to the development of material|analyzed the data|performed the pharmacological experiments and histological investigation|wrote the manuscript	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5492466	28713408	F-SZ	PLoS52	conceived and designed the research|contributed to the development of material|analyzed the data|performed the pharmacological experiments and histological investigation|wrote the manuscript	contributed to the development of material	Contributed reagents/materials/analysis tools	Resources	YES
5492466	28713408	F-SZ	PLoS52	conceived and designed the research|contributed to the development of material|analyzed the data|performed the pharmacological experiments and histological investigation|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5492466	28713408	F-SZ	PLoS52	conceived and designed the research|contributed to the development of material|analyzed the data|performed the pharmacological experiments and histological investigation|wrote the manuscript	performed the pharmacological experiments and histological investigation	Performed the experiments	Investigation	YES
5492466	28713408	F-SZ	PLoS52	conceived and designed the research|contributed to the development of material|analyzed the data|performed the pharmacological experiments and histological investigation|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5492466	28713408	FM	PLoS52	analyzed the data|edited the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5492466	28713408	FM	PLoS52	analyzed the data|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5492466	28713408	L-JY	PLoS52	contributed to the development of material	contributed to the development of material	Contributed reagents/materials/analysis tools	Resources	YES
5492466	28713408	M-FX	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5492466	28713408	S-JG	PLoS52	contributed to the development of material|performed the pharmacological experiments and histological investigation	contributed to the development of material	Contributed reagents/materials/analysis tools	Resources	YES
5492466	28713408	S-JG	PLoS52	contributed to the development of material|performed the pharmacological experiments and histological investigation	performed the pharmacological experiments and histological investigation	Performed the experiments	Investigation	YES
5492466	28713408	W-QS	PLoS52	contributed to the development of material	contributed to the development of material	Contributed reagents/materials/analysis tools	Resources	YES
5492466	28713408	X-JZ	PLoS52	contributed to the development of material	contributed to the development of material	Contributed reagents/materials/analysis tools	Resources	YES
3425811	22927783	S. L. Lee	2	contributed equally to the paper	contributed equally to the paper	-	-	NO
3425811	22927783	T. H. Lam	2	contributed equally to the paper	contributed equally to the paper	-	-	NO
3834523	24245779	CB	2	performed ccr5 genotyping	performed ccr5 genotyping	Performed the experiments	Investigation	YES
3834523	24245779	DN	2	performed the micro array	performed the micro array	Performed the experiments	Investigation	YES
3834523	24245779	GH	2	designed to study and wrote the manuscript	designed to study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3834523	24245779	HK	2	contributed to conception and design of the study and interpretation of the data	contributed to conception and design of the study and interpretation of the data	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Methodology|Resources	YES
3834523	24245779	MN	2	analyzed micro array data	analyzed micro array data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3834523	24245779	MR	2	contributed to conception and design of the study and interpretation of the data	contributed to conception and design of the study and interpretation of the data	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Methodology|Resources	YES
5143459	27927177	DHA	2	made substantial contributions to conception and design of the study|acquired and analyzed data|interpreted data|drafted the manuscript and revised it critically for important intellectual content|gave final approval of the version to be published, take public responsibility for appropriate portions of the content and agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	made substantial contributions to conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5143459	27927177	DHA	2	made substantial contributions to conception and design of the study|acquired and analyzed data|interpreted data|drafted the manuscript and revised it critically for important intellectual content|gave final approval of the version to be published, take public responsibility for appropriate portions of the content and agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	acquired and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5143459	27927177	DHA	2	made substantial contributions to conception and design of the study|acquired and analyzed data|interpreted data|drafted the manuscript and revised it critically for important intellectual content|gave final approval of the version to be published, take public responsibility for appropriate portions of the content and agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	interpreted data	Analyzed the data	Formal analysis	YES
5143459	27927177	DHA	2	made substantial contributions to conception and design of the study|acquired and analyzed data|interpreted data|drafted the manuscript and revised it critically for important intellectual content|gave final approval of the version to be published, take public responsibility for appropriate portions of the content and agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	drafted the manuscript and revised it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5143459	27927177	DHA	2	made substantial contributions to conception and design of the study|acquired and analyzed data|interpreted data|drafted the manuscript and revised it critically for important intellectual content|gave final approval of the version to be published, take public responsibility for appropriate portions of the content and agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	gave final approval of the version to be published, take public responsibility for appropriate portions of the content and agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	-	-	NO
5143459	27927177	YMH	2	made substantial contributions to conception and design of the study|interpreted data|drafted the manuscript and revised it critically for important intellectual content|gave final approval of the version to be published, take public responsibility for appropriate portions of the content and agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	made substantial contributions to conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5143459	27927177	YMH	2	made substantial contributions to conception and design of the study|interpreted data|drafted the manuscript and revised it critically for important intellectual content|gave final approval of the version to be published, take public responsibility for appropriate portions of the content and agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	interpreted data	Analyzed the data	Formal analysis	YES
5143459	27927177	YMH	2	made substantial contributions to conception and design of the study|interpreted data|drafted the manuscript and revised it critically for important intellectual content|gave final approval of the version to be published, take public responsibility for appropriate portions of the content and agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	drafted the manuscript and revised it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5143459	27927177	YMH	2	made substantial contributions to conception and design of the study|interpreted data|drafted the manuscript and revised it critically for important intellectual content|gave final approval of the version to be published, take public responsibility for appropriate portions of the content and agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	gave final approval of the version to be published, take public responsibility for appropriate portions of the content and agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	-	-	NO
4401774	25885897	JFZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401774	25885897	KW	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4401774	25885897	KW	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4401774	25885897	KW	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401774	25885897	MHY	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401774	25885897	XQJ	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401774	25885897	YF	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401774	25885897	YMZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401774	25885897	YYJ	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4588402	26498496	ACL	2	performed the statistical analysis|group members contributed to patient recruitment	performed the statistical analysis	Analyzed the data	Formal analysis	YES
4588402	26498496	ACL	2	performed the statistical analysis|group members contributed to patient recruitment	group members contributed to patient recruitment	Performed the experiments	Investigation	YES
4588402	26498496	AMG	2	designed the study|managed study governance and patient recruitment|wrote the manuscript, which was reviewed by all authors	designed the study	Conceived and designed the experiments	Methodology	YES
4588402	26498496	AMG	2	designed the study|managed study governance and patient recruitment|wrote the manuscript, which was reviewed by all authors	managed study governance and patient recruitment	Performed the experiments	Investigation|Project administration	YES
4588402	26498496	AMG	2	designed the study|managed study governance and patient recruitment|wrote the manuscript, which was reviewed by all authors	wrote the manuscript, which was reviewed by all authors	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4588402	26498496	AP	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
4588402	26498496	AR	2	wrote the manuscript, which was reviewed by all authors	wrote the manuscript, which was reviewed by all authors	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4588402	26498496	The Eras Study	2	group members contributed to patient recruitment	group members contributed to patient recruitment	Performed the experiments	Investigation	YES
4284445	25568796	JKHL	2	was involved in the study concept and design, data collection, data analysis and interpretation and writing of the paper	was involved in the study concept and design, data collection, data analysis and interpretation and writing of the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5684866	28805975	Fang Jung	2	conducted the experiments|performed data analysis	conducted the experiments	Performed the experiments	Investigation	YES
5684866	28805975	Fang Jung	2	conducted the experiments|performed data analysis	performed data analysis	Analyzed the data	Formal analysis	YES
5684866	28805975	Guey-Mei Jow	2	wrote or contributed to the writing of the manuscript	wrote or contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5684866	28805975	Hwei-Ling Chou	2	participated in research design	participated in research design	Conceived and designed the experiments	-	YES
5684866	28805975	Jau-Chen Lin	2	participated in research design|performed data analysis|wrote or contributed to the writing of the manuscript	participated in research design	Conceived and designed the experiments	-	YES
5684866	28805975	Jau-Chen Lin	2	participated in research design|performed data analysis|wrote or contributed to the writing of the manuscript	performed data analysis	Analyzed the data	Formal analysis	YES
5684866	28805975	Jau-Chen Lin	2	participated in research design|performed data analysis|wrote or contributed to the writing of the manuscript	wrote or contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5684866	28805975	Shao-Ting Chou	2	participated in research design	participated in research design	Conceived and designed the experiments	-	YES
5684866	28805975	Shih-Hsing Yang	2	conducted the experiments|performed data analysis	conducted the experiments	Performed the experiments	Investigation	YES
5684866	28805975	Shih-Hsing Yang	2	conducted the experiments|performed data analysis	performed data analysis	Analyzed the data	Formal analysis	YES
5492483	28713415	AB	2	carried out experimental work|wrote the main manuscript	carried out experimental work	Performed the experiments	Investigation	YES
5492483	28713415	AB	2	carried out experimental work|wrote the main manuscript	wrote the main manuscript	Wrote the paper	Writing - Original Draft	YES
5492483	28713415	AM	2	carried out experimental work	carried out experimental work	Performed the experiments	Investigation	YES
5492483	28713415	AS	2	conceived and coordinated the study|wrote the main manuscript	conceived and coordinated the study	Conceived and designed the experiments	Conceptualization|Project administration	YES
5492483	28713415	AS	2	conceived and coordinated the study|wrote the main manuscript	wrote the main manuscript	Wrote the paper	Writing - Original Draft	YES
5492483	28713415	All authors	2	contributed to discussing and interpreting the data at all stages	contributed to discussing and interpreting the data at all stages	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5492483	28713415	EA	2	carried out experimental work|wrote the main manuscript	carried out experimental work	Performed the experiments	Investigation	YES
5492483	28713415	EA	2	carried out experimental work|wrote the main manuscript	wrote the main manuscript	Wrote the paper	Writing - Original Draft	YES
5492483	28713415	SC	2	carried out experimental work	carried out experimental work	Performed the experiments	Investigation	YES
3847291	24010677	AB	2	carried out data collection, data entry and helped draft the manuscript	carried out data collection, data entry and helped draft the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Investigation|Writing - Original Draft	YES
3847291	24010677	CS	2	carried out data collection, statistical analysis and drafted the manuscript	carried out data collection, statistical analysis and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3847291	24010677	GS	2	helped conceive the study and draft the manuscript	helped conceive the study and draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
3847291	24010677	JL	2	helped draft the manuscript	helped draft the manuscript	Wrote the paper	Writing - Original Draft	YES
3847291	24010677	PWGM	2	conceived the study, supervised the statistical analysis and helped draft the manuscript	conceived the study, supervised the statistical analysis and helped draft the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Supervision|Writing - Original Draft	YES
4401775	25885547	ER	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401775	25885547	ER	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401775	25885547	ER	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401775	25885547	ER	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401775	25885547	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401775	25885547	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401775	25885547	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401775	25885547	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401775	25885547	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401775	25885547	JLW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401775	25885547	JLW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401775	25885547	JLW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401775	25885547	JLW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
514541	15287962	BL	2	carried out the phylogenetic analyses, the gene context study and drafted the manuscript which was further improved by all authors	carried out the phylogenetic analyses, the gene context study and drafted the manuscript which was further improved by all authors	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
514541	15287962	NG	2	dug up the ancient data on putrescine carbamoyltransferase, contributed his knowledge about carbamoyltransferases and made important additions to the manuscript	dug up the ancient data on putrescine carbamoyltransferase, contributed his knowledge about carbamoyltransferases and made important additions to the manuscript	-	-	NO
514541	15287962	YX	2	brought essential informations about the genetics and biochemistry of the enzymes involved in arginine metabolism and their evolution	brought essential informations about the genetics and biochemistry of the enzymes involved in arginine metabolism and their evolution	Performed the experiments	Investigation	YES
5684868	28805976	Paul Scowen	2	assisted in animal research ethics	assisted in animal research ethics	-	-	NO
5684868	28805976	Rajaraman Eri	2	proposed the idea and wrote the manuscript	proposed the idea and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5684868	28805976	Rajkumar Cheluvappa	2	wrote and submitted the manuscript	wrote and submitted the manuscript	Wrote the paper	Writing - Original Draft	YES
5492488	28713398	CY	PLoS5	Performed by	Performed by	Performed the experiments	Investigation	YES
5492488	28713398	GL	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5492488	28713398	GW	PLoS5	The experiments was conceived and designed|Performed by|Wrote the paper	The experiments was conceived and designed	Conceived and designed the experiments	Conceptualization|Methodology	YES
5492488	28713398	GW	PLoS5	The experiments was conceived and designed|Performed by|Wrote the paper	Performed by	Performed the experiments	Investigation	YES
5492488	28713398	GW	PLoS5	The experiments was conceived and designed|Performed by|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5492488	28713398	JH	PLoS5	Performed by	Performed by	Performed the experiments	Investigation	YES
5492488	28713398	JN	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5492488	28713398	JZ	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5492488	28713398	XC	PLoS5	Performed by	Performed by	Performed the experiments	Investigation	YES
5492488	28713398	XZ	PLoS5	The experiments was conceived and designed|Performed by|Wrote the paper	The experiments was conceived and designed	Conceived and designed the experiments	Conceptualization|Methodology	YES
5492488	28713398	XZ	PLoS5	The experiments was conceived and designed|Performed by|Wrote the paper	Performed by	Performed the experiments	Investigation	YES
5492488	28713398	XZ	PLoS5	The experiments was conceived and designed|Performed by|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5492488	28713398	ZW	PLoS5	The experiments was conceived and designed|Wrote the paper	The experiments was conceived and designed	Conceived and designed the experiments	Conceptualization|Methodology	YES
5492488	28713398	ZW	PLoS5	The experiments was conceived and designed|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401776	25884566	AM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401776	25884566	AN	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401776	25884566	BB	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401776	25884566	CEW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401776	25884566	CEW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401776	25884566	CEW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401776	25884566	CEW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401776	25884566	CN	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401776	25884566	CN	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4401776	25884566	CN	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401776	25884566	FM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401776	25884566	NM	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401776	25884566	RN	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401776	25884566	RN	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4401776	25884566	RN	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401776	25884566	TA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401776	25884566	TA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401776	25884566	TA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401776	25884566	TA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401776	25884566	TA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3874602	24252301	BP	2	conceived the study, performed the assays and drafted the manuscript	conceived the study, performed the assays and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
3874602	24252301	DAP	2	conceived and helped coordinate the study	conceived and helped coordinate the study	Conceived and designed the experiments	Conceptualization|Project administration	YES
3874602	24252301	PFC	2	conceived the study and drafted the manuscript	conceived the study and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4588424	26501105	ACA	2	anterior cerebral artery	anterior cerebral artery	-	-	NO
4588424	26501105	All authors	2	participated in the finalization of the report	participated in the finalization of the report	-	-	NO
4588424	26501105	BA	2	basilar artery	basilar artery	-	-	NO
4588424	26501105	CDR	2	clinical dementia rating	clinical dementia rating	-	-	NO
4588424	26501105	CY	2	are responsible for the conception and design of the study|participated in data collection|made the statistical analysis plan|made literature search	are responsible for the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4588424	26501105	CY	2	are responsible for the conception and design of the study|participated in data collection|made the statistical analysis plan|made literature search	participated in data collection	Performed the experiments	Investigation	YES
4588424	26501105	CY	2	are responsible for the conception and design of the study|participated in data collection|made the statistical analysis plan|made literature search	made the statistical analysis plan	Analyzed the data	Formal analysis	YES
4588424	26501105	CY	2	are responsible for the conception and design of the study|participated in data collection|made the statistical analysis plan|made literature search	made literature search	-	Formal analysis	YES
4588424	26501105	DBP	2	diastolic blood pressure	diastolic blood pressure	Performed the experiments	Investigation	YES
4588424	26501105	EM	2	made data interpretation	made data interpretation	Analyzed the data	Formal analysis	YES
4588424	26501105	HDL	2	high density lipoprotein	high density lipoprotein	Performed the experiments	Investigation	YES
4588424	26501105	HM	2	participated in data collection	participated in data collection	Performed the experiments	Investigation	YES
4588424	26501105	HO	2	made the statistical analysis plan|performed the statistical analysis	made the statistical analysis plan	Analyzed the data	Formal analysis	YES
4588424	26501105	HO	2	made the statistical analysis plan|performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
4588424	26501105	KK	2	are responsible for the conception and design of the study|participated in data collection|contributed to draft the report	are responsible for the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4588424	26501105	KK	2	are responsible for the conception and design of the study|participated in data collection|contributed to draft the report	participated in data collection	Performed the experiments	Investigation	YES
4588424	26501105	KK	2	are responsible for the conception and design of the study|participated in data collection|contributed to draft the report	contributed to draft the report	Wrote the paper	Writing - Original Draft	YES
4588424	26501105	KM	2	are responsible for the conception and design of the study|participated in data collection|made the statistical analysis plan|contributed to draft the report	are responsible for the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4588424	26501105	KM	2	are responsible for the conception and design of the study|participated in data collection|made the statistical analysis plan|contributed to draft the report	participated in data collection	Performed the experiments	Investigation	YES
4588424	26501105	KM	2	are responsible for the conception and design of the study|participated in data collection|made the statistical analysis plan|contributed to draft the report	made the statistical analysis plan	Analyzed the data	Formal analysis	YES
4588424	26501105	KM	2	are responsible for the conception and design of the study|participated in data collection|made the statistical analysis plan|contributed to draft the report	contributed to draft the report	Wrote the paper	Writing - Original Draft	YES
4588424	26501105	LDL	2	low density lipoprotein	low density lipoprotein	Performed the experiments	Investigation	YES
4588424	26501105	MCA	2	middle cerebral artery	middle cerebral artery	-	-	NO
4588424	26501105	MF	2	are responsible for the conception and design of the study|made the statistical analysis plan|performed the statistical analysis	are responsible for the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4588424	26501105	MF	2	are responsible for the conception and design of the study|made the statistical analysis plan|performed the statistical analysis	made the statistical analysis plan	Analyzed the data	Formal analysis	YES
4588424	26501105	MF	2	are responsible for the conception and design of the study|made the statistical analysis plan|performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
4588424	26501105	MM	2	is the principal investigator|are responsible for the conception and design of the study|participated in data collection|made the statistical analysis plan|made data interpretation|designed the figures|made literature search|contributed to draft the report	is the principal investigator	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
4588424	26501105	MM	2	is the principal investigator|are responsible for the conception and design of the study|participated in data collection|made the statistical analysis plan|made data interpretation|designed the figures|made literature search|contributed to draft the report	are responsible for the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4588424	26501105	MM	2	is the principal investigator|are responsible for the conception and design of the study|participated in data collection|made the statistical analysis plan|made data interpretation|designed the figures|made literature search|contributed to draft the report	participated in data collection	Performed the experiments	Investigation	YES
4588424	26501105	MM	2	is the principal investigator|are responsible for the conception and design of the study|participated in data collection|made the statistical analysis plan|made data interpretation|designed the figures|made literature search|contributed to draft the report	made the statistical analysis plan	Analyzed the data	Formal analysis	YES
4588424	26501105	MM	2	is the principal investigator|are responsible for the conception and design of the study|participated in data collection|made the statistical analysis plan|made data interpretation|designed the figures|made literature search|contributed to draft the report	made data interpretation	Analyzed the data	Formal analysis	YES
4588424	26501105	MM	2	is the principal investigator|are responsible for the conception and design of the study|participated in data collection|made the statistical analysis plan|made data interpretation|designed the figures|made literature search|contributed to draft the report	designed the figures	Conceived and designed the experiments	Visualization	YES
4588424	26501105	MM	2	is the principal investigator|are responsible for the conception and design of the study|participated in data collection|made the statistical analysis plan|made data interpretation|designed the figures|made literature search|contributed to draft the report	made literature search	-	Formal analysis	YES
4588424	26501105	MM	2	is the principal investigator|are responsible for the conception and design of the study|participated in data collection|made the statistical analysis plan|made data interpretation|designed the figures|made literature search|contributed to draft the report	contributed to draft the report	Wrote the paper	Writing - Original Draft	YES
4588424	26501105	MN	2	made data interpretation	made data interpretation	Analyzed the data	Formal analysis	YES
4588424	26501105	MT	2	participated in data collection	participated in data collection	Performed the experiments	Investigation	YES
4588424	26501105	NH	2	participated in data collection|made the statistical analysis plan|made data interpretation|designed the figures|made literature search|contributed to draft the report	participated in data collection	Performed the experiments	Investigation	YES
4588424	26501105	NH	2	participated in data collection|made the statistical analysis plan|made data interpretation|designed the figures|made literature search|contributed to draft the report	made the statistical analysis plan	Analyzed the data	Formal analysis	YES
4588424	26501105	NH	2	participated in data collection|made the statistical analysis plan|made data interpretation|designed the figures|made literature search|contributed to draft the report	made data interpretation	Analyzed the data	Formal analysis	YES
4588424	26501105	NH	2	participated in data collection|made the statistical analysis plan|made data interpretation|designed the figures|made literature search|contributed to draft the report	designed the figures	Conceived and designed the experiments	Visualization	YES
4588424	26501105	NH	2	participated in data collection|made the statistical analysis plan|made data interpretation|designed the figures|made literature search|contributed to draft the report	made literature search	-	Formal analysis	YES
4588424	26501105	NH	2	participated in data collection|made the statistical analysis plan|made data interpretation|designed the figures|made literature search|contributed to draft the report	contributed to draft the report	Wrote the paper	Writing - Original Draft	YES
4588424	26501105	NS	2	participated in data collection	participated in data collection	Performed the experiments	Investigation	YES
4588424	26501105	PCA	2	posterior cerebral artery	posterior cerebral artery	-	-	NO
4588424	26501105	SA	2	participated in data collection|made the statistical analysis plan	participated in data collection	Performed the experiments	Investigation	YES
4588424	26501105	SA	2	participated in data collection|made the statistical analysis plan	made the statistical analysis plan	Analyzed the data	Formal analysis	YES
4588424	26501105	SBP	2	systolic blood pressure	systolic blood pressure	Performed the experiments	Investigation	YES
4588424	26501105	SI	2	are responsible for the conception and design of the study|participated in data collection|made the statistical analysis plan	are responsible for the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4588424	26501105	SI	2	are responsible for the conception and design of the study|participated in data collection|made the statistical analysis plan	participated in data collection	Performed the experiments	Investigation	YES
4588424	26501105	SI	2	are responsible for the conception and design of the study|participated in data collection|made the statistical analysis plan	made the statistical analysis plan	Analyzed the data	Formal analysis	YES
4588424	26501105	SU	2	are responsible for the conception and design of the study|participated in data collection|made the statistical analysis plan|contributed to draft the report	are responsible for the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4588424	26501105	SU	2	are responsible for the conception and design of the study|participated in data collection|made the statistical analysis plan|contributed to draft the report	participated in data collection	Performed the experiments	Investigation	YES
4588424	26501105	SU	2	are responsible for the conception and design of the study|participated in data collection|made the statistical analysis plan|contributed to draft the report	made the statistical analysis plan	Analyzed the data	Formal analysis	YES
4588424	26501105	SU	2	are responsible for the conception and design of the study|participated in data collection|made the statistical analysis plan|contributed to draft the report	contributed to draft the report	Wrote the paper	Writing - Original Draft	YES
4588424	26501105	TIA	2	atherothrombotic infarction, lacunar infarction, and intracranial hemorrhage in pre-defined subgroups|transient ischemic attack	atherothrombotic infarction, lacunar infarction, and intracranial hemorrhage in pre-defined subgroups	-	-	NO
4588424	26501105	TIA	2	atherothrombotic infarction, lacunar infarction, and intracranial hemorrhage in pre-defined subgroups|transient ischemic attack	transient ischemic attack	-	-	NO
4588424	26501105	TK	2	are responsible for the conception and design of the study|participated in data collection|made literature search	are responsible for the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4588424	26501105	TK	2	are responsible for the conception and design of the study|participated in data collection|made literature search	participated in data collection	Performed the experiments	Investigation	YES
4588424	26501105	TK	2	are responsible for the conception and design of the study|participated in data collection|made literature search	made literature search	-	Formal analysis	YES
4588424	26501105	TN	2	participated in data collection	participated in data collection	Performed the experiments	Investigation	YES
4588424	26501105	TO	2	participated in data collection	participated in data collection	Performed the experiments	Investigation	YES
4588424	26501105	TY	2	made data interpretation	made data interpretation	Analyzed the data	Formal analysis	YES
4588424	26501105	VA	2	vertebral artery	vertebral artery	-	-	NO
4588424	26501105	YN	2	are responsible for the conception and design of the study|participated in data collection|made the statistical analysis plan|performed the statistical analysis|made data interpretation|designed the figures|made literature search|contributed to draft the report	are responsible for the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4588424	26501105	YN	2	are responsible for the conception and design of the study|participated in data collection|made the statistical analysis plan|performed the statistical analysis|made data interpretation|designed the figures|made literature search|contributed to draft the report	participated in data collection	Performed the experiments	Investigation	YES
4588424	26501105	YN	2	are responsible for the conception and design of the study|participated in data collection|made the statistical analysis plan|performed the statistical analysis|made data interpretation|designed the figures|made literature search|contributed to draft the report	made the statistical analysis plan	Analyzed the data	Formal analysis	YES
4588424	26501105	YN	2	are responsible for the conception and design of the study|participated in data collection|made the statistical analysis plan|performed the statistical analysis|made data interpretation|designed the figures|made literature search|contributed to draft the report	performed the statistical analysis	Analyzed the data	Formal analysis	YES
4588424	26501105	YN	2	are responsible for the conception and design of the study|participated in data collection|made the statistical analysis plan|performed the statistical analysis|made data interpretation|designed the figures|made literature search|contributed to draft the report	made data interpretation	Analyzed the data	Formal analysis	YES
4588424	26501105	YN	2	are responsible for the conception and design of the study|participated in data collection|made the statistical analysis plan|performed the statistical analysis|made data interpretation|designed the figures|made literature search|contributed to draft the report	designed the figures	Conceived and designed the experiments	Visualization	YES
4588424	26501105	YN	2	are responsible for the conception and design of the study|participated in data collection|made the statistical analysis plan|performed the statistical analysis|made data interpretation|designed the figures|made literature search|contributed to draft the report	made literature search	-	Formal analysis	YES
4588424	26501105	YN	2	are responsible for the conception and design of the study|participated in data collection|made the statistical analysis plan|performed the statistical analysis|made data interpretation|designed the figures|made literature search|contributed to draft the report	contributed to draft the report	Wrote the paper	Writing - Original Draft	YES
4588424	26501105	YS	2	participated in data collection	participated in data collection	Performed the experiments	Investigation	YES
4588424	26501105	YT	2	participated in data collection	participated in data collection	Performed the experiments	Investigation	YES
4284448	25568789	Claudia Filisetti	7	data collection and description of the clinical case	data collection and description of the clinical case	Performed the experiments	Investigation	YES
4284448	25568789	Giovanna Riccipetitoni	7	review and interpretation	review and interpretation	Analyzed the data	Formal analysis	YES
4284448	25568789	Lorenzo Cobianchi	7	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4284448	25568789	Mario Alessiani	7	general review	general review	-	-	NO
4284448	25568789	Paolo Dionigi	7	review and interpretation	review and interpretation	Analyzed the data	Formal analysis	YES
4284448	25568789	Sandro Zonta	7	data collection and description of the clinical case	data collection and description of the clinical case	Performed the experiments	Investigation	YES
4284448	25568789	Tommaso Dominioni	7	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5146858	27931189	AM	PLoS52	supervised the work	supervised the work	-	Supervision	YES
5146858	27931189	AN	PLoS52	performed the statistical analyses and ncrna detection and quantification	performed the statistical analyses and ncrna detection and quantification	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5146858	27931189	AT	PLoS52	participated in its compilation	participated in its compilation	-	-	NO
5146858	27931189	EB	PLoS52	quantified the amino acids, sugars and organic acids	quantified the amino acids, sugars and organic acids	-	-	NO
5146858	27931189	FA	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5146858	27931189	GH	PLoS52	quantified the amino acids, sugars and organic acids	quantified the amino acids, sugars and organic acids	-	-	NO
5146858	27931189	HF	PLoS52	wrote the paper|mapped the rna seq data and reconstructed the pathways	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5146858	27931189	HF	PLoS52	wrote the paper|mapped the rna seq data and reconstructed the pathways	mapped the rna seq data and reconstructed the pathways	Performed the experiments	Investigation	YES
5146858	27931189	HP	PLoS52	compiled the library and performed the sequencing	compiled the library and performed the sequencing	Performed the experiments	Investigation	YES
5146858	27931189	MBM	PLoS52	quantified the amino acids, sugars and organic acids	quantified the amino acids, sugars and organic acids	-	-	NO
5146858	27931189	MNM	PLoS52	cared for the strain	cared for the strain	Performed the experiments	Investigation	YES
5146858	27931189	MR	PLoS52	undertook the demultiplexing and quality control of the reads obtained	undertook the demultiplexing and quality control of the reads obtained	Performed the experiments	Investigation|Validation	YES
5146858	27931189	SMD	PLoS52	participated in its compilation	participated in its compilation	-	-	NO
5146858	27931189	SP	PLoS52	performed quantitative pcr	performed quantitative pcr	Performed the experiments	Investigation	YES
5146858	27931189	VA	PLoS52	supervised the work	supervised the work	-	Supervision	YES
5146858	27931189	YLL	PLoS52	supervised the work	supervised the work	-	Supervision	YES
5492558	28713410	BH	2	designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
5492558	28713410	KG	2	designed the research|performed the research|analyzed the data and prepared figures	designed the research	Conceived and designed the experiments	Methodology	YES
5492558	28713410	KG	2	designed the research|performed the research|analyzed the data and prepared figures	performed the research	Performed the experiments	Investigation	YES
5492558	28713410	KG	2	designed the research|performed the research|analyzed the data and prepared figures	analyzed the data and prepared figures	Analyzed the data	Formal analysis|Visualization	YES
5492558	28713410	LL	2	designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
5492558	28713410	XL	2	performed the research|analyzed the data and prepared figures	performed the research	Performed the experiments	Investigation	YES
5492558	28713410	XL	2	performed the research|analyzed the data and prepared figures	analyzed the data and prepared figures	Analyzed the data	Formal analysis|Visualization	YES
5492558	28713410	XyL	2	analyzed the data and prepared figures	analyzed the data and prepared figures	Analyzed the data	Formal analysis|Visualization	YES
5723698	29226628	A.T.	2	participated in the study design, performed the data analysis and interpretation of the results, and wrote the manuscript	participated in the study design, performed the data analysis and interpretation of the results, and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5723698	29226628	A.V.	2	participated in the study design, interpretation of the results, and approved the final manuscript	participated in the study design, interpretation of the results, and approved the final manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
5723698	29226628	D.R.H.H.	2	participated in the study design, interpretation of the results, and approved the final manuscript	participated in the study design, interpretation of the results, and approved the final manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
5723698	29226628	E.C.M.D.	2	participated in the study design, supervised the experimental procedures, participated in the interpretation of the results, and approved the final manuscript	participated in the study design, supervised the experimental procedures, participated in the interpretation of the results, and approved the final manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Supervision|Writing - Review & Editing	YES
5723698	29226628	J.H.P.	2	participated in the study design, performed the data analysis and interpretation of the results, and approved the final manuscript	participated in the study design, performed the data analysis and interpretation of the results, and approved the final manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
5723698	29226628	M.D.	2	participated in the study design, interpretation of the results, and approved the final manuscript	participated in the study design, interpretation of the results, and approved the final manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
3874610	24330597	AAP	7	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
3874610	24330597	AGP	7	conceived and drafted the manuscript	conceived and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
3874610	24330597	MCNF	7	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4401778	25886553	DP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401778	25886553	EBL	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401778	25886553	ELH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401778	25886553	ELH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401778	25886553	ELH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401778	25886553	ELH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401778	25886553	ELH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401778	25886553	LP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401778	25886553	MJB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401778	25886553	MJB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401778	25886553	MJB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401778	25886553	MJB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401778	25886553	MJB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401778	25886553	PFL	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401778	25886553	PGM	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401778	25886553	SER	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401778	25886553	SER	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4284449	25568791	DSN	2	did public health literature search	did public health literature search	-	Formal analysis	YES
4284449	25568791	EPW	2	is the main author	is the main author	Wrote the paper	Writing - Original Draft	YES
4284449	25568791	GE	2	made pathological research	made pathological research	Performed the experiments	Investigation	YES
4284449	25568791	HCC	2	in the absence of cirrhosis|in the setting of cirrhosis which is better treated by transplantation than resection|may remain poor because of late diagnosis	in the absence of cirrhosis	-	-	NO
4284449	25568791	HCC	2	in the absence of cirrhosis|in the setting of cirrhosis which is better treated by transplantation than resection|may remain poor because of late diagnosis	in the setting of cirrhosis which is better treated by transplantation than resection	Performed the experiments	Investigation	YES
4284449	25568791	HCC	2	in the absence of cirrhosis|in the setting of cirrhosis which is better treated by transplantation than resection|may remain poor because of late diagnosis	may remain poor because of late diagnosis	Performed the experiments	Investigation	YES
4284449	25568791	MNN	2	gave advice and performed some literature search	gave advice and performed some literature search	Performed the experiments	Formal analysis|Investigation	YES
4284449	25568791	TACE	2	may predict disease-free survival after liver transplantation	may predict disease-free survival after liver transplantation	Analyzed the data	Formal analysis	YES
3093813	21584207	CS	2	participated in collection and interpretation of data, and revising the manuscript addressing the reviewers comments	participated in collection and interpretation of data, and revising the manuscript addressing the reviewers comments	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
3093813	21584207	FM	2	participated in the design of the study, collection of data, and drafting the manuscript	participated in the design of the study, collection of data, and drafting the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
3093813	21584207	RKN	2	conceived and participated in the design of the study and revision of the manuscript	conceived and participated in the design of the study and revision of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
4378238	25094039	E.A.R.	4	The manuscript was written by	The manuscript was written by	Wrote the paper	Writing - Original Draft	YES
4378238	25094039	M.J.B.	4	The manuscript was written by	The manuscript was written by	Wrote the paper	Writing - Original Draft	YES
4378238	25094039	S.B.	4	The manuscript was written by	The manuscript was written by	Wrote the paper	Writing - Original Draft	YES
5146892	27931183	DMR	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5146892	27931183	KT	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5146892	27931183	LX	PLoS52	conceived and designed the experiments|analyzed the data|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5146892	27931183	LX	PLoS52	conceived and designed the experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5146892	27931183	LX	PLoS52	conceived and designed the experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5146892	27931183	LZ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5146892	27931183	MAF	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5146892	27931183	NL	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5146892	27931183	SL	PLoS52	performed the experiments|analyzed the data|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5146892	27931183	SL	PLoS52	performed the experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5146892	27931183	SL	PLoS52	performed the experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5146892	27931183	YF	PLoS52	conceived and designed the experiments|analyzed the data|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5146892	27931183	YF	PLoS52	conceived and designed the experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5146892	27931183	YF	PLoS52	conceived and designed the experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5146892	27931183	YG	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
3096051	21594002	CEN	7	performed surgery, revision of manuscript	performed surgery, revision of manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
3096051	21594002	PHR	7	conception of case report, writing the manuscript, literature search	conception of case report, writing the manuscript, literature search	Conceived and designed the experiments|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
4284450	25568800	Afrim Avdaj	2	contributed primarily to the design of the study, data collecting and drafted the manuscript	contributed primarily to the design of the study, data collecting and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Methodology|Resources|Writing - Original Draft	YES
4284450	25568800	Sadie Namani	2	made substantive intellectual contributions and participated in comparing the results with other publications, analysis and interpretation of data	made substantive intellectual contributions and participated in comparing the results with other publications, analysis and interpretation of data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5492635	28713400	AL	2	conceived and designed the research|wrote the manuscript	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5492635	28713400	AL	2	conceived and designed the research|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5492635	28713400	FW	2	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5492635	28713400	GA	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5492635	28713400	HZ	2	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5492635	28713400	JL	2	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5492635	28713400	MW	2	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5492635	28713400	SC	2	conceived and designed the research|performed the experiments and analyzed the data|wrote the manuscript	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5492635	28713400	SC	2	conceived and designed the research|performed the experiments and analyzed the data|wrote the manuscript	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5492635	28713400	SC	2	conceived and designed the research|performed the experiments and analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5492635	28713400	ZW	2	supervised the study	supervised the study	-	Supervision	YES
3874614	24330617	ACA	2	both performed the literature search and planned the structure of the review|conducted the review and wrote the first draft and subsequent changes to the manuscript	both performed the literature search and planned the structure of the review	Conceived and designed the experiments|Performed the experiments	Conceptualization|Formal analysis|Investigation	YES
3874614	24330617	ACA	2	both performed the literature search and planned the structure of the review|conducted the review and wrote the first draft and subsequent changes to the manuscript	conducted the review and wrote the first draft and subsequent changes to the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
3874614	24330617	MAB	2	conceived the idea|both performed the literature search and planned the structure of the review|provided key input to the contents and provided overall supervision of the project	conceived the idea	Conceived and designed the experiments	Conceptualization	YES
3874614	24330617	MAB	2	conceived the idea|both performed the literature search and planned the structure of the review|provided key input to the contents and provided overall supervision of the project	both performed the literature search and planned the structure of the review	Conceived and designed the experiments|Performed the experiments	Conceptualization|Formal analysis|Investigation	YES
3874614	24330617	MAB	2	conceived the idea|both performed the literature search and planned the structure of the review|provided key input to the contents and provided overall supervision of the project	provided key input to the contents and provided overall supervision of the project	-	Supervision	YES
4401779	25885257	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401779	25885257	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401779	25885257	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401779	25885257	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401779	25885257	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401779	25885257	KLK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401779	25885257	KLK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401779	25885257	KLK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401779	25885257	KS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401779	25885257	KS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401779	25885257	KS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401779	25885257	KS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401779	25885257	KS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5723704	29226623	C.E.W.	2	conceived the study and designed the protocol|collected and analyzed data|wrote the manuscript	conceived the study and designed the protocol	Conceived and designed the experiments	Conceptualization|Methodology	YES
5723704	29226623	C.E.W.	2	conceived the study and designed the protocol|collected and analyzed data|wrote the manuscript	collected and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5723704	29226623	C.E.W.	2	conceived the study and designed the protocol|collected and analyzed data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5723704	29226623	J.A.A.	2	conceived the study and designed the protocol|collected and analyzed data|wrote the manuscript	conceived the study and designed the protocol	Conceived and designed the experiments	Conceptualization|Methodology	YES
5723704	29226623	J.A.A.	2	conceived the study and designed the protocol|collected and analyzed data|wrote the manuscript	collected and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5723704	29226623	J.A.A.	2	conceived the study and designed the protocol|collected and analyzed data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5723704	29226623	R.J.A.H.	2	performed wire myography studies|collected and analyzed data|critically reviewed the manuscript	performed wire myography studies	Performed the experiments	Investigation	YES
5723704	29226623	R.J.A.H.	2	performed wire myography studies|collected and analyzed data|critically reviewed the manuscript	collected and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5723704	29226623	R.J.A.H.	2	performed wire myography studies|collected and analyzed data|critically reviewed the manuscript	critically reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5146901	27931190	All authors	2	were involved in preparing and writing the manuscript and approved the final version	were involved in preparing and writing the manuscript and approved the final version	Wrote the paper	Writing - Original Draft	YES
5146901	27931190	FZG	2	worked for fish husbandry, sample collecting and bioinformatics analysis	worked for fish husbandry, sample collecting and bioinformatics analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5146901	27931190	JC	2	were responsible for gene rhythmic expression analysis	were responsible for gene rhythmic expression analysis	Performed the experiments	Investigation	YES
5146901	27931190	JSZ	2	conceived and designed the study and wrote the paper	conceived and designed the study and wrote the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
5146901	27931190	LC	2	were responsible for gene rhythmic expression analysis	were responsible for gene rhythmic expression analysis	Performed the experiments	Investigation	YES
5146901	27931190	PW	2	performed the experiments including rna extraction, cdna synthesis, and bioinformatics analysis	performed the experiments including rna extraction, cdna synthesis, and bioinformatics analysis	Performed the experiments	Formal analysis|Investigation	YES
5146901	27931190	WYC	2	conceived and designed the study and wrote the paper	conceived and designed the study and wrote the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
5146901	27931190	XZ	2	worked for fish husbandry, sample collecting and bioinformatics analysis	worked for fish husbandry, sample collecting and bioinformatics analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5146901	27931190	YLL	2	worked for fish husbandry, sample collecting and bioinformatics analysis	worked for fish husbandry, sample collecting and bioinformatics analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4378457	25495456	All authors	2	have given approval to the final version of the manuscript	have given approval to the final version of the manuscript	-	-	NO
4634194	26629533	BS	2	contributed to the design of the study, and contributed significantly to the manuscript	contributed to the design of the study, and contributed significantly to the manuscript	Conceived and designed the experiments	Methodology	YES
4634194	26629533	CP	2	reviewed the paper and made a contribution to the discussion	reviewed the paper and made a contribution to the discussion	Wrote the paper	Writing - Review & Editing	YES
4634194	26629533	HC	2	read the paper and provided suggestions to the discussion	read the paper and provided suggestions to the discussion	-	-	NO
4634194	26629533	HD	2	contributed to the imputation dataset	contributed to the imputation dataset	Contributed reagents/materials/analysis tools	Resources	YES
4634194	26629533	NT	2	reviewed the paper and made a contribution to the discussion	reviewed the paper and made a contribution to the discussion	Wrote the paper	Writing - Review & Editing	YES
4634194	26629533	WM	2	analysed the data and prepared the manuscript	analysed the data and prepared the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4634194	26629533	YL	2	contributed to e-health linkage dataset	contributed to e-health linkage dataset	Contributed reagents/materials/analysis tools	Resources	YES
3104563	21633722	All authors	2	have made substantial contributions to conception and design of the review and the drafting and revising of the manuscript	have made substantial contributions to conception and design of the review and the drafting and revising of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
5492642	28713393	CF	PLoS52	conceived the ideas	conceived the ideas	Conceived and designed the experiments	Conceptualization	YES
5492642	28713393	JW	PLoS52	contributed to the sampling	contributed to the sampling	Performed the experiments	Investigation	YES
5492642	28713393	LL	PLoS52	conceived the ideas|contributed to the sampling|performed the experiment|analyzed the data	conceived the ideas	Conceived and designed the experiments	Conceptualization	YES
5492642	28713393	LL	PLoS52	conceived the ideas|contributed to the sampling|performed the experiment|analyzed the data	contributed to the sampling	Performed the experiments	Investigation	YES
5492642	28713393	LL	PLoS52	conceived the ideas|contributed to the sampling|performed the experiment|analyzed the data	performed the experiment	Performed the experiments	Investigation	YES
5492642	28713393	LL	PLoS52	conceived the ideas|contributed to the sampling|performed the experiment|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5492642	28713393	PL	PLoS52	conceived the ideas	conceived the ideas	Conceived and designed the experiments	Conceptualization	YES
5492642	28713393	RL	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5492642	28713393	XL	PLoS52	conceived the ideas	conceived the ideas	Conceived and designed the experiments	Conceptualization	YES
4401781	25884209	AH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401781	25884209	AH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401781	25884209	AH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401781	25884209	AH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401781	25884209	AJGH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401781	25884209	AJGH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401781	25884209	AJGH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401781	25884209	AvdL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401781	25884209	AvdL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401781	25884209	AvdL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401781	25884209	AvdL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401781	25884209	AvdL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401781	25884209	CD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401781	25884209	CD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401781	25884209	CD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401781	25884209	CY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401781	25884209	CY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401781	25884209	CY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401781	25884209	CY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401781	25884209	DV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401781	25884209	DV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401781	25884209	DV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401781	25884209	DV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401781	25884209	DV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401781	25884209	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401781	25884209	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401781	25884209	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401781	25884209	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401781	25884209	JGV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401781	25884209	JGV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401781	25884209	JGV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401781	25884209	JGV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401781	25884209	JGV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401781	25884209	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401781	25884209	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401781	25884209	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401781	25884209	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401781	25884209	MdeV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401781	25884209	MdeV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401781	25884209	MdeV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401781	25884209	MdeV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401781	25884209	MdeV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401781	25884209	NvR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401781	25884209	NvR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401781	25884209	NvR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401781	25884209	PQ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401781	25884209	PQ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401781	25884209	PQ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401781	25884209	PQ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401781	25884209	RF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401781	25884209	RF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401781	25884209	RF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401781	25884209	RF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401781	25884209	SN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401781	25884209	SN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401781	25884209	SN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401781	25884209	SN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401781	25884209	SN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401781	25884209	TvdPK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401781	25884209	TvdPK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401781	25884209	TvdPK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5146904	27931186	CB	2	realized the experiments	realized the experiments	-	-	NO
5146904	27931186	CMC	2	participated in the study design|realized the experiments|performed computational and data analysis, and drafted the manuscript with comments from all authors	participated in the study design	Conceived and designed the experiments	Methodology	YES
5146904	27931186	CMC	2	participated in the study design|realized the experiments|performed computational and data analysis, and drafted the manuscript with comments from all authors	realized the experiments	-	-	NO
5146904	27931186	CMC	2	participated in the study design|realized the experiments|performed computational and data analysis, and drafted the manuscript with comments from all authors	performed computational and data analysis, and drafted the manuscript with comments from all authors	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5146904	27931186	ITB	2	participated in the study design	participated in the study design	Conceived and designed the experiments	Methodology	YES
5146907	27931182	AMOD	2	performed pyrosequencing for candidates	performed pyrosequencing for candidates	Performed the experiments	Investigation	YES
5146907	27931182	AT	2	performed pyrosequencing for candidates	performed pyrosequencing for candidates	Performed the experiments	Investigation	YES
5146907	27931182	CPW	2	supervised the pyrosequencing work	supervised the pyrosequencing work	Performed the experiments	Investigation|Supervision	YES
5146907	27931182	DG	2	performed the microarray analysis	performed the microarray analysis	Performed the experiments	Investigation	YES
5146907	27931182	EF	2	performed bioinformatic analyses	performed bioinformatic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5146907	27931182	JLMRL	2	supervised the overall work|drafted the final manuscript	supervised the overall work	-	Supervision	YES
5146907	27931182	JLMRL	2	supervised the overall work|drafted the final manuscript	drafted the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5146907	27931182	KLJD	2	performed bovine in vitro embryo production and was involved in carrying out microarray and pyrosequencing|drafted the final manuscript	performed bovine in vitro embryo production and was involved in carrying out microarray and pyrosequencing	Performed the experiments	Investigation	YES
5146907	27931182	KLJD	2	performed bovine in vitro embryo production and was involved in carrying out microarray and pyrosequencing|drafted the final manuscript	drafted the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5146907	27931182	PEJB	2	supervised the overall work	supervised the overall work	-	Supervision	YES
5146907	27931182	VVH	2	drafted the final manuscript	drafted the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4634196	26629542	AEA	2	wrote the manuscript|conceived the study	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4634196	26629542	AEA	2	wrote the manuscript|conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4634196	26629542	AMP	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4634196	26629542	All authors	2	contributed to the design of the study	contributed to the design of the study	Conceived and designed the experiments	Methodology	YES
4634196	26629542	CKM	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4634196	26629542	HD	2	wrote the manuscript|conceived the study	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4634196	26629542	HD	2	wrote the manuscript|conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4634196	26629542	JGB	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4634196	26629542	PB	2	wrote the manuscript|performed all statistical analyses	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4634196	26629542	PB	2	wrote the manuscript|performed all statistical analyses	performed all statistical analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4634196	26629542	SHA	2	wrote the manuscript|conceived the study|performed all statistical analyses	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4634196	26629542	SHA	2	wrote the manuscript|conceived the study|performed all statistical analyses	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4634196	26629542	SHA	2	wrote the manuscript|conceived the study|performed all statistical analyses	performed all statistical analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4634196	26629542	SK	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4634196	26629542	SMU	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4634196	26629542	TNW	2	wrote the manuscript|conceived the study	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4634196	26629542	TNW	2	wrote the manuscript|conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4409634	25680316	AB	2	designed the study|performed the laboratory experiments|drafted the paper	designed the study	Conceived and designed the experiments	Methodology	YES
4409634	25680316	AB	2	designed the study|performed the laboratory experiments|drafted the paper	performed the laboratory experiments	Performed the experiments	Investigation	YES
4409634	25680316	AB	2	designed the study|performed the laboratory experiments|drafted the paper	drafted the paper	Wrote the paper	Writing - Original Draft	YES
4409634	25680316	CYP	2	designed the study|drafted the paper	designed the study	Conceived and designed the experiments	Methodology	YES
4409634	25680316	CYP	2	designed the study|drafted the paper	drafted the paper	Wrote the paper	Writing - Original Draft	YES
4409634	25680316	EvN	2	collected the clinical data	collected the clinical data	Performed the experiments	Investigation	YES
4409634	25680316	GRD	2	drafted the paper	drafted the paper	Wrote the paper	Writing - Original Draft	YES
4409634	25680316	NGR	2	collected the clinical data|performed the statistical analysis|drafted the paper	collected the clinical data	Performed the experiments	Investigation	YES
4409634	25680316	NGR	2	collected the clinical data|performed the statistical analysis|drafted the paper	performed the statistical analysis	Analyzed the data	Formal analysis	YES
4409634	25680316	NGR	2	collected the clinical data|performed the statistical analysis|drafted the paper	drafted the paper	Wrote the paper	Writing - Original Draft	YES
4409634	25680316	NV	2	performed the laboratory experiments	performed the laboratory experiments	Performed the experiments	Investigation	YES
4409634	25680316	PFdG	2	collected the clinical data	collected the clinical data	Performed the experiments	Investigation	YES
4409634	25680316	RK	2	collected the clinical data	collected the clinical data	Performed the experiments	Investigation	YES
4409634	25680316	TvG	2	designed the study|drafted the paper	designed the study	Conceived and designed the experiments	Methodology	YES
4409634	25680316	TvG	2	designed the study|drafted the paper	drafted the paper	Wrote the paper	Writing - Original Draft	YES
4409634	25680316	all authors	2	critically reviewed the manuscript	critically reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
4401783	25886537	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401783	25886537	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401783	25886537	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401783	25886537	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401783	25886537	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401783	25886537	MR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401783	25886537	MR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401783	25886537	MR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401783	25886537	MR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401783	25886537	MR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5492656	28713409	CX	2	performed the experiments, analyzed the data, wrote the paper, reviewed drafts of the paper	performed the experiments, analyzed the data, wrote the paper, reviewed drafts of the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5492656	28713409	WD	2	conceived and designed the experiments, performed the experiments, conducted the chloroplast genome assembling, analyzed the data, wrote the paper, prepared figures, and/or tables, reviewed drafts of the paper	conceived and designed the experiments, performed the experiments, conducted the chloroplast genome assembling, analyzed the data, wrote the paper, prepared figures, and/or tables, reviewed drafts of the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Visualization|Writing - Original Draft|Writing - Review & Editing	YES
5492656	28713409	WL	2	conceived and designed the experiments, contributed reagents/materials/analysis tools, wrote the paper, reviewed drafts of the paper	conceived and designed the experiments, contributed reagents/materials/analysis tools, wrote the paper, reviewed drafts of the paper	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5492656	28713409	XJ	2	wrote the paper, reviewed drafts of the paper	wrote the paper, reviewed drafts of the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5492656	28713409	XX	2	conceived and designed the experiments, contributed reagents/materials/analysis tools, wrote the paper, reviewed drafts of the paper	conceived and designed the experiments, contributed reagents/materials/analysis tools, wrote the paper, reviewed drafts of the paper	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5492656	28713409	YaL	2	performed the experiments, prepared figures and/or tables	performed the experiments, prepared figures and/or tables	Performed the experiments	Investigation|Visualization	YES
5492656	28713409	YiL	2	conceived and designed the experiments, contributed reagents/materials/analysis tools, wrote the paper, reviewed drafts of the paper	conceived and designed the experiments, contributed reagents/materials/analysis tools, wrote the paper, reviewed drafts of the paper	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5492656	28713409	ZS	2	conceived and designed the experiments, performed the experiments, analyzed the data, contributed reagents/materials/analysis tools, wrote the paper, reviewed drafts of the paper	conceived and designed the experiments, performed the experiments, analyzed the data, contributed reagents/materials/analysis tools, wrote the paper, reviewed drafts of the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
3874658	24330529	DH	2	contributed to the writing of the manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
3874658	24330529	IS	2	contributed to the writing of the manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
3874658	24330529	JA	2	contributed to the writing of the manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
4452251	26090410	Lucia Jimenez	2	contributed equally to this work	contributed equally to this work	-	-	NO
4452251	26090410	Oscar Rodriguez-Lima	2	contributed equally to this work	contributed equally to this work	-	-	NO
5148847	27938335	All authors	2	reviewed and approved the manuscript	reviewed and approved the manuscript	Wrote the paper	Writing - Review & Editing	YES
5148847	27938335	HSY	2	participated in the design of the study	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
5148847	27938335	JEM	2	provided the lycaon samples|participated in the design of the study	provided the lycaon samples	Contributed reagents/materials/analysis tools	Resources	YES
5148847	27938335	JEM	2	provided the lycaon samples|participated in the design of the study	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
5148847	27938335	KHM	2	conceived the study|participated in the design of the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5148847	27938335	KHM	2	conceived the study|participated in the design of the study	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
5148847	27938335	LDP	2	performed bioinformatics analyses and contributed to the manuscript	performed bioinformatics analyses and contributed to the manuscript	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5148847	27938335	MGC	2	performed the molecular genetic assays, carried out bioinformatics analyses, and wrote the manuscript	performed the molecular genetic assays, carried out bioinformatics analyses, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5148847	27938335	MSG	2	provided the lycaon samples	provided the lycaon samples	Contributed reagents/materials/analysis tools	Resources	YES
5148847	27938335	MTRH	2	performed bioinformatics analyses and contributed to the manuscript	performed bioinformatics analyses and contributed to the manuscript	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5148847	27938335	RFC	2	conceived the study|participated in the design of the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5148847	27938335	RFC	2	conceived the study|participated in the design of the study	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
5148847	27938335	RW	2	provided the lycaon samples|participated in the design of the study	provided the lycaon samples	Contributed reagents/materials/analysis tools	Resources	YES
5148847	27938335	RW	2	provided the lycaon samples|participated in the design of the study	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
3874682	24330537	BD	2	contributed to the drafting of the manuscript	contributed to the drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
3874682	24330537	GR	2	contributed to the drafting of the manuscript	contributed to the drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
4634197	26629551	CMR	2	participated in data collection|participated in data analysis and interpretation|did the final statistical analysis	participated in data collection	Performed the experiments	Investigation	YES
4634197	26629551	CMR	2	participated in data collection|participated in data analysis and interpretation|did the final statistical analysis	participated in data analysis and interpretation	Analyzed the data	Formal analysis	YES
4634197	26629551	CMR	2	participated in data collection|participated in data analysis and interpretation|did the final statistical analysis	did the final statistical analysis	Analyzed the data	Formal analysis	YES
4634197	26629551	HN	2	participated in data collection	participated in data collection	Performed the experiments	Investigation	YES
4634197	26629551	MS	2	participated in data analysis and interpretation|drafted the report	participated in data analysis and interpretation	Analyzed the data	Formal analysis	YES
4634197	26629551	MS	2	participated in data analysis and interpretation|drafted the report	drafted the report	Wrote the paper	Writing - Original Draft	YES
4634197	26629551	MT	2	participated in data collection|participated in data analysis and interpretation	participated in data collection	Performed the experiments	Investigation	YES
4634197	26629551	MT	2	participated in data collection|participated in data analysis and interpretation	participated in data analysis and interpretation	Analyzed the data	Formal analysis	YES
4634197	26629551	NH	2	conceived the study design	conceived the study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4634197	26629551	SK	2	conceived the study design|provided critical revision of the draft	conceived the study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4634197	26629551	SK	2	conceived the study design|provided critical revision of the draft	provided critical revision of the draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4634197	26629551	TT	2	conceived the study design|participated in data analysis and interpretation	conceived the study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4634197	26629551	TT	2	conceived the study design|participated in data analysis and interpretation	participated in data analysis and interpretation	Analyzed the data	Formal analysis	YES
4634197	26629551	TvZ	2	conceived the study design|participated in data analysis and interpretation|drafted the report	conceived the study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4634197	26629551	TvZ	2	conceived the study design|participated in data analysis and interpretation|drafted the report	participated in data analysis and interpretation	Analyzed the data	Formal analysis	YES
4634197	26629551	TvZ	2	conceived the study design|participated in data analysis and interpretation|drafted the report	drafted the report	Wrote the paper	Writing - Original Draft	YES
4634197	26629551	YA	2	conceived the study design|participated in data collection|participated in data analysis and interpretation|drafted the report	conceived the study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4634197	26629551	YA	2	conceived the study design|participated in data collection|participated in data analysis and interpretation|drafted the report	participated in data collection	Performed the experiments	Investigation	YES
4634197	26629551	YA	2	conceived the study design|participated in data collection|participated in data analysis and interpretation|drafted the report	participated in data analysis and interpretation	Analyzed the data	Formal analysis	YES
4634197	26629551	YA	2	conceived the study design|participated in data collection|participated in data analysis and interpretation|drafted the report	drafted the report	Wrote the paper	Writing - Original Draft	YES
4634197	26629551	YAbe	2	participated in data collection|participated in data analysis and interpretation|assisted with data preparation	participated in data collection	Performed the experiments	Investigation	YES
4634197	26629551	YAbe	2	participated in data collection|participated in data analysis and interpretation|assisted with data preparation	participated in data analysis and interpretation	Analyzed the data	Formal analysis	YES
4634197	26629551	YAbe	2	participated in data collection|participated in data analysis and interpretation|assisted with data preparation	assisted with data preparation	-	-	NO
5492659	28713413	HZ	2	performed the experimental work	performed the experimental work	Performed the experiments	Investigation	YES
5492659	28713413	JG	2	participated in the discussions, produced the first draft and the revised manuscript	participated in the discussions, produced the first draft and the revised manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5492659	28713413	JY	2	planned the project and designed the experiments|participated in the discussions, produced the first draft and the revised manuscript	planned the project and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5492659	28713413	JY	2	planned the project and designed the experiments|participated in the discussions, produced the first draft and the revised manuscript	participated in the discussions, produced the first draft and the revised manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5492659	28713413	XG	2	planned the project and designed the experiments|participated in the discussions, produced the first draft and the revised manuscript	planned the project and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5492659	28713413	XG	2	planned the project and designed the experiments|participated in the discussions, produced the first draft and the revised manuscript	participated in the discussions, produced the first draft and the revised manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5492659	28713413	XL	2	performed the experimental work	performed the experimental work	Performed the experiments	Investigation	YES
5492659	28713413	YL	2	planned the project and designed the experiments|participated in the discussions, produced the first draft and the revised manuscript	planned the project and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5492659	28713413	YL	2	planned the project and designed the experiments|participated in the discussions, produced the first draft and the revised manuscript	participated in the discussions, produced the first draft and the revised manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3892092	24373498	A.J.S.D.	2	is the responsable of the laboratory and revised the work critically	is the responsable of the laboratory and revised the work critically	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
3892092	24373498	A.P.	2	conceived of the study, coordinated its design, performed statistical analysis and wrote the manuscript	conceived of the study, coordinated its design, performed statistical analysis and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Project administration|Writing - Original Draft	YES
3892092	24373498	B.T.S.	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
3892092	24373498	T.M.H.	2	is the responsable of the work group, contributed in conceiving and designing the study, analysis and interpretation of data and drafting the manuscript	is the responsable of the work group, contributed in conceiving and designing the study, analysis and interpretation of data and drafting the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Methodology|Resources|Writing - Original Draft	YES
4401784	25884507	FLT	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401784	25884507	FLT	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401784	25884507	JSL	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401784	25884507	JSL	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401784	25884507	JSL	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401784	25884507	JSL	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401784	25884507	LCS	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401784	25884507	LCS	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401784	25884507	LCS	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401784	25884507	LCS	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401784	25884507	MJC	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4634199	26629536	Adeel Razi	1	Analysis of the imaging data	Analysis of the imaging data	Analyzed the data	Formal analysis|Visualization	YES
4634199	26629536	Alexandra Durr	1	Conception, organization and execution of the trackon-hd research project	Conception, organization and execution of the trackon-hd research project	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Project administration	YES
4634199	26629536	Bernhard Landwehrmeyer	1	Conception, organization and execution of the trackon-hd research project	Conception, organization and execution of the trackon-hd research project	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Project administration	YES
4634199	26629536	Beth Borowsky	1	Conception, organization and execution of the trackon-hd research project	Conception, organization and execution of the trackon-hd research project	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Project administration	YES
4634199	26629536	Blair Leavitt	1	Conception, organization and execution of the trackon-hd research project	Conception, organization and execution of the trackon-hd research project	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Project administration	YES
4634199	26629536	Elisa Scheller	1	Analysis of the imaging data	Analysis of the imaging data	Analyzed the data	Formal analysis|Visualization	YES
4634199	26629536	Gail Owen	1	Conception, organization and execution of the trackon-hd research project	Conception, organization and execution of the trackon-hd research project	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Project administration	YES
4634199	26629536	Geraint Rees	1	Conception, organization and execution of the trackon-hd research project|Analysis of the imaging data	Conception, organization and execution of the trackon-hd research project	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Project administration	YES
4634199	26629536	Geraint Rees	1	Conception, organization and execution of the trackon-hd research project|Analysis of the imaging data	Analysis of the imaging data	Analyzed the data	Formal analysis|Visualization	YES
4634199	26629536	Hans Johnson	1	Conception, organization and execution of the trackon-hd research project	Conception, organization and execution of the trackon-hd research project	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Project administration	YES
4634199	26629536	James Mills	1	Analyses	Analyses	Analyzed the data	Formal analysis	YES
4634199	26629536	Jeffrey Long	1	Analyses	Analyses	Analyzed the data	Formal analysis	YES
4634199	26629536	Julie Stout	1	Conception, organization and execution of the trackon-hd research project	Conception, organization and execution of the trackon-hd research project	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Project administration	YES
4634199	26629536	Lora Minkova	1	Analysis of the imaging data	Analysis of the imaging data	Analyzed the data	Formal analysis|Visualization	YES
4634199	26629536	Marina Papoutsi	1	Conception, organization and execution of the trackon-hd research project	Conception, organization and execution of the trackon-hd research project	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Project administration	YES
4634199	26629536	Rachael Scahill	1	Conception, organization and execution of the trackon-hd research project|Analysis of the imaging data	Conception, organization and execution of the trackon-hd research project	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Project administration	YES
4634199	26629536	Rachael Scahill	1	Conception, organization and execution of the trackon-hd research project|Analysis of the imaging data	Analysis of the imaging data	Analyzed the data	Formal analysis|Visualization	YES
4634199	26629536	Ralf Reilmann	1	Conception, organization and execution of the trackon-hd research project	Conception, organization and execution of the trackon-hd research project	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Project administration	YES
4634199	26629536	Raymund Roos	1	Conception, organization and execution of the trackon-hd research project	Conception, organization and execution of the trackon-hd research project	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Project administration	YES
4634199	26629536	Sarah Gregory	1	Analysis of the imaging data|Writing of the manuscript	Analysis of the imaging data	Analyzed the data	Formal analysis|Visualization	YES
4634199	26629536	Sarah Gregory	1	Analysis of the imaging data|Writing of the manuscript	Writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
4634199	26629536	Sarah Tabrizi	1	Conception, organization and execution of the trackon-hd research project	Conception, organization and execution of the trackon-hd research project	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Project administration	YES
4634199	26629536	Stefan Kloppel	1	Conception, organization and execution of the trackon-hd research project|Analysis of the imaging data|Writing of the manuscript	Conception, organization and execution of the trackon-hd research project	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Project administration	YES
4634199	26629536	Stefan Kloppel	1	Conception, organization and execution of the trackon-hd research project|Analysis of the imaging data|Writing of the manuscript	Analysis of the imaging data	Analyzed the data	Formal analysis|Visualization	YES
4634199	26629536	Stefan Kloppel	1	Conception, organization and execution of the trackon-hd research project|Analysis of the imaging data|Writing of the manuscript	Writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
3432353	22973175	J. Gu	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
3432353	22973175	J. Rong	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
5492763	28713412	BL	2	conceived and designed the paper	conceived and designed the paper	Conceived and designed the experiments	Conceptualization	YES
5492763	28713412	DD	2	conceived and designed the paper|collected and analyzed the literature|drafted the paper|prepared the figures|revised the manuscript	conceived and designed the paper	Conceived and designed the experiments	Conceptualization	YES
5492763	28713412	DD	2	conceived and designed the paper|collected and analyzed the literature|drafted the paper|prepared the figures|revised the manuscript	collected and analyzed the literature	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5492763	28713412	DD	2	conceived and designed the paper|collected and analyzed the literature|drafted the paper|prepared the figures|revised the manuscript	drafted the paper	Wrote the paper	Writing - Original Draft	YES
5492763	28713412	DD	2	conceived and designed the paper|collected and analyzed the literature|drafted the paper|prepared the figures|revised the manuscript	prepared the figures	-	Visualization	YES
5492763	28713412	DD	2	conceived and designed the paper|collected and analyzed the literature|drafted the paper|prepared the figures|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5492763	28713412	DF	2	collected and analyzed the literature|prepared the figures|revised the manuscript	collected and analyzed the literature	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5492763	28713412	DF	2	collected and analyzed the literature|prepared the figures|revised the manuscript	prepared the figures	-	Visualization	YES
5492763	28713412	DF	2	collected and analyzed the literature|prepared the figures|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5492763	28713412	JY	2	collected and analyzed the literature|prepared the figures	collected and analyzed the literature	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5492763	28713412	JY	2	collected and analyzed the literature|prepared the figures	prepared the figures	-	Visualization	YES
5492763	28713412	KD	2	conceived and designed the paper|collected and analyzed the literature|drafted the paper	conceived and designed the paper	Conceived and designed the experiments	Conceptualization	YES
5492763	28713412	KD	2	conceived and designed the paper|collected and analyzed the literature|drafted the paper	collected and analyzed the literature	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5492763	28713412	KD	2	conceived and designed the paper|collected and analyzed the literature|drafted the paper	drafted the paper	Wrote the paper	Writing - Original Draft	YES
5492763	28713412	LW	2	collected and analyzed the literature|prepared the figures|revised the manuscript	collected and analyzed the literature	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5492763	28713412	LW	2	collected and analyzed the literature|prepared the figures|revised the manuscript	prepared the figures	-	Visualization	YES
5492763	28713412	LW	2	collected and analyzed the literature|prepared the figures|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5492763	28713412	LY	2	collected and analyzed the literature|drafted the paper	collected and analyzed the literature	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5492763	28713412	LY	2	collected and analyzed the literature|drafted the paper	drafted the paper	Wrote the paper	Writing - Original Draft	YES
5492763	28713412	MM	2	collected and analyzed the literature|drafted the paper	collected and analyzed the literature	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5492763	28713412	MM	2	collected and analyzed the literature|drafted the paper	drafted the paper	Wrote the paper	Writing - Original Draft	YES
5492763	28713412	MN	2	collected and analyzed the literature|revised the manuscript	collected and analyzed the literature	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5492763	28713412	MN	2	collected and analyzed the literature|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5492763	28713412	NC	2	conceived and designed the paper|revised the manuscript	conceived and designed the paper	Conceived and designed the experiments	Conceptualization	YES
5492763	28713412	NC	2	conceived and designed the paper|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5492763	28713412	XW	2	collected and analyzed the literature|revised the manuscript	collected and analyzed the literature	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5492763	28713412	XW	2	collected and analyzed the literature|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5492763	28713412	XZ	2	conceived and designed the paper|revised the manuscript	conceived and designed the paper	Conceived and designed the experiments	Conceptualization	YES
5492763	28713412	XZ	2	conceived and designed the paper|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5492763	28713412	YZ	2	collected and analyzed the literature|revised the manuscript	collected and analyzed the literature	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5492763	28713412	YZ	2	collected and analyzed the literature|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
3899605	24428886	CAP	CRediT	Concept and design|Drafting|Revision	Concept and design	Conceived and designed the experiments	Conceptualization	YES
3899605	24428886	CAP	CRediT	Concept and design|Drafting|Revision	Drafting	Wrote the paper	Writing - Original Draft	YES
3899605	24428886	CAP	CRediT	Concept and design|Drafting|Revision	Revision	Wrote the paper	Writing - Review & Editing	YES
3899605	24428886	CT	CRediT	Concept and design|Revision	Concept and design	Conceived and designed the experiments	Conceptualization	YES
3899605	24428886	CT	CRediT	Concept and design|Revision	Revision	Wrote the paper	Writing - Review & Editing	YES
3899605	24428886	CTM	CRediT	Concept and design|Data collection and performing experiments|Drafting	Concept and design	Conceived and designed the experiments	Conceptualization	YES
3899605	24428886	CTM	CRediT	Concept and design|Data collection and performing experiments|Drafting	Data collection and performing experiments	Performed the experiments	Investigation	YES
3899605	24428886	CTM	CRediT	Concept and design|Data collection and performing experiments|Drafting	Drafting	Wrote the paper	Writing - Original Draft	YES
3899605	24428886	JNY	CRediT	Concept and design|Revision|Supervision	Concept and design	Conceived and designed the experiments	Conceptualization	YES
3899605	24428886	JNY	CRediT	Concept and design|Revision|Supervision	Revision	Wrote the paper	Writing - Review & Editing	YES
3899605	24428886	JNY	CRediT	Concept and design|Revision|Supervision	Supervision	-	Supervision	YES
3899605	24428886	JRNN	CRediT	Analysis|Drafting|Revision	Analysis	-	-	NO
3899605	24428886	JRNN	CRediT	Analysis|Drafting|Revision	Drafting	Wrote the paper	Writing - Original Draft	YES
3899605	24428886	JRNN	CRediT	Analysis|Drafting|Revision	Revision	Wrote the paper	Writing - Review & Editing	YES
3899605	24428886	TCM	CRediT	Revision	Revision	Wrote the paper	Writing - Review & Editing	YES
3899605	24428886	VJAM	CRediT	Concept and design|Data collection and performing experiments|Revision	Concept and design	Conceived and designed the experiments	Conceptualization	YES
3899605	24428886	VJAM	CRediT	Concept and design|Data collection and performing experiments|Revision	Data collection and performing experiments	Performed the experiments	Investigation	YES
3899605	24428886	VJAM	CRediT	Concept and design|Data collection and performing experiments|Revision	Revision	Wrote the paper	Writing - Review & Editing	YES
4306058	25628887	AA	7	Conception and design of study, acquisition and analysis of data, initial draft of the article	Conception and design of study, acquisition and analysis of data, initial draft of the article	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4306058	25628887	MA	7	Interpretation of data, draft and revising article for critical intellectual content	Interpretation of data, draft and revising article for critical intellectual content	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
4306058	25628887	MK	7	Interpretation of data, draft and revising article for critical intellectual content	Interpretation of data, draft and revising article for critical intellectual content	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
4306058	25628887	MMA	7	Interpretation of data, draft and revising article for critical intellectual content	Interpretation of data, draft and revising article for critical intellectual content	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
4306058	25628887	NS	7	Draft and revising article for critical intellectual content	Draft and revising article for critical intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5148876	27938347	AD	2	designed the research project|performed all experiments and collected sequence data	designed the research project	Conceived and designed the experiments	Methodology	YES
5148876	27938347	AD	2	designed the research project|performed all experiments and collected sequence data	performed all experiments and collected sequence data	Performed the experiments	Investigation	YES
5148876	27938347	BH	2	implemented analytical tools and performed analysis|wrote the manuscript	implemented analytical tools and performed analysis	Performed the experiments	Investigation	YES
5148876	27938347	BH	2	implemented analytical tools and performed analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5148876	27938347	CMKS	2	implemented analytical tools and performed analysis|wrote the manuscript	implemented analytical tools and performed analysis	Performed the experiments	Investigation	YES
5148876	27938347	CMKS	2	implemented analytical tools and performed analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5148876	27938347	CRG	2	designed the research project|performed all experiments and collected sequence data|implemented analytical tools and performed analysis|wrote the manuscript	designed the research project	Conceived and designed the experiments	Methodology	YES
5148876	27938347	CRG	2	designed the research project|performed all experiments and collected sequence data|implemented analytical tools and performed analysis|wrote the manuscript	performed all experiments and collected sequence data	Performed the experiments	Investigation	YES
5148876	27938347	CRG	2	designed the research project|performed all experiments and collected sequence data|implemented analytical tools and performed analysis|wrote the manuscript	implemented analytical tools and performed analysis	Performed the experiments	Investigation	YES
5148876	27938347	CRG	2	designed the research project|performed all experiments and collected sequence data|implemented analytical tools and performed analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5148876	27938347	DH	2	implemented analytical tools and performed analysis|wrote the manuscript	implemented analytical tools and performed analysis	Performed the experiments	Investigation	YES
5148876	27938347	DH	2	implemented analytical tools and performed analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5148876	27938347	MH	2	implemented analytical tools and performed analysis	implemented analytical tools and performed analysis	Performed the experiments	Investigation	YES
5148876	27938347	MM	2	implemented analytical tools and performed analysis	implemented analytical tools and performed analysis	Performed the experiments	Investigation	YES
5148876	27938347	MS	2	implemented analytical tools and performed analysis	implemented analytical tools and performed analysis	Performed the experiments	Investigation	YES
5148876	27938347	RB	2	implemented analytical tools and performed analysis	implemented analytical tools and performed analysis	Performed the experiments	Investigation	YES
5148876	27938347	UG	2	implemented analytical tools and performed analysis|wrote the manuscript	implemented analytical tools and performed analysis	Performed the experiments	Investigation	YES
5148876	27938347	UG	2	implemented analytical tools and performed analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4306064	25628889	AF	7	Performed surgery, drafting manuscript, final approval	Performed surgery, drafting manuscript, final approval	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4306064	25628889	NS	7	Assisted manuscript draft, critical revision, final approval	Assisted manuscript draft, critical revision, final approval	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4306064	25628889	TB	7	Performed surgery, project supervision, critical revision, final approval project, revision of manuscript	Performed surgery, project supervision, critical revision, final approval project, revision of manuscript	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Review & Editing	YES
4401785	25886063	FK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401785	25886063	FK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401785	25886063	FK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401785	25886063	FK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401785	25886063	FK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401785	25886063	HC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401785	25886063	HC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401785	25886063	YZ	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4401785	25886063	YZ	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
3899924	24422713	AF	2	conceived the study, and participated in its design and coordination and helped to draft the manuscript	conceived the study, and participated in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
3899924	24422713	AK	2	carried out fibril preperations	carried out fibril preperations	Performed the experiments	Investigation	YES
3899924	24422713	DW	2	conceived the study, and participated in its design and coordination and helped to draft the manuscript	conceived the study, and participated in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
3899924	24422713	HS	2	conceived the study, and participated in its design and coordination and helped to draft the manuscript	conceived the study, and participated in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
3899924	24422713	MW	2	conceived, designed, and performed hiv-related infection and readout experiments, performed the statistical analysis and drafted the manuscript	conceived, designed, and performed hiv-related infection and readout experiments, performed the statistical analysis and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
3899924	24422713	YC	2	carried out fibril preperations	carried out fibril preperations	Performed the experiments	Investigation	YES
4306093	25628888	AA	7	Conception and design of study, acquisition and analysis of data, initial draft of the article	Conception and design of study, acquisition and analysis of data, initial draft of the article	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4306093	25628888	MA	7	Interpretation of data, draft and revising article for critical intellectual content	Interpretation of data, draft and revising article for critical intellectual content	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
4306093	25628888	NS	7	Draft and revising article for critical intellectual content	Draft and revising article for critical intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4306093	25628888	OS	7	Interpretation of data, draft and revising article for critical intellectual content	Interpretation of data, draft and revising article for critical intellectual content	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
4634361	26629534	All authors	1	Study design and protocol development|Interpretation of data and drafting of the manuscript|Critical revision of the manuscript for important intellectual content	Study design and protocol development	Conceived and designed the experiments	Methodology	YES
4634361	26629534	All authors	1	Study design and protocol development|Interpretation of data and drafting of the manuscript|Critical revision of the manuscript for important intellectual content	Interpretation of data and drafting of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4634361	26629534	All authors	1	Study design and protocol development|Interpretation of data and drafting of the manuscript|Critical revision of the manuscript for important intellectual content	Critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
3900935	24450960	AKM	2	helped design the study|acquired, analysed and interpreted the data|drafted the manuscript	helped design the study	Conceived and designed the experiments	Methodology	YES
3900935	24450960	AKM	2	helped design the study|acquired, analysed and interpreted the data|drafted the manuscript	acquired, analysed and interpreted the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3900935	24450960	AKM	2	helped design the study|acquired, analysed and interpreted the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
3900935	24450960	ASD	2	have revised it critically for important intellectual content	have revised it critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
3900935	24450960	All authors	2	have given final approval of the version to be published	have given final approval of the version to be published	-	-	NO
3900935	24450960	FJP	2	have revised it critically for important intellectual content	have revised it critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
3900935	24450960	LAK	2	have revised it critically for important intellectual content	have revised it critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
3900935	24450960	MDW	2	have revised it critically for important intellectual content	have revised it critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
3900935	24450960	TTB	2	conceived of the study|helped design the study|acquired, analysed and interpreted the data|have revised it critically for important intellectual content	conceived of the study	Conceived and designed the experiments	Conceptualization	YES
3900935	24450960	TTB	2	conceived of the study|helped design the study|acquired, analysed and interpreted the data|have revised it critically for important intellectual content	helped design the study	Conceived and designed the experiments	Methodology	YES
3900935	24450960	TTB	2	conceived of the study|helped design the study|acquired, analysed and interpreted the data|have revised it critically for important intellectual content	acquired, analysed and interpreted the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3900935	24450960	TTB	2	conceived of the study|helped design the study|acquired, analysed and interpreted the data|have revised it critically for important intellectual content	have revised it critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5492765	28713416	AO	2	designed the greenhouse experiments|carried out the greenhouse experiments|designed the hydrolysis probe assay experiment|carried out the assay development|conducted out most of the analysis and wrote the manuscript	designed the greenhouse experiments	Conceived and designed the experiments	Methodology	YES
5492765	28713416	AO	2	designed the greenhouse experiments|carried out the greenhouse experiments|designed the hydrolysis probe assay experiment|carried out the assay development|conducted out most of the analysis and wrote the manuscript	carried out the greenhouse experiments	Performed the experiments	Investigation	YES
5492765	28713416	AO	2	designed the greenhouse experiments|carried out the greenhouse experiments|designed the hydrolysis probe assay experiment|carried out the assay development|conducted out most of the analysis and wrote the manuscript	designed the hydrolysis probe assay experiment	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5492765	28713416	AO	2	designed the greenhouse experiments|carried out the greenhouse experiments|designed the hydrolysis probe assay experiment|carried out the assay development|conducted out most of the analysis and wrote the manuscript	carried out the assay development	Performed the experiments	Investigation	YES
5492765	28713416	AO	2	designed the greenhouse experiments|carried out the greenhouse experiments|designed the hydrolysis probe assay experiment|carried out the assay development|conducted out most of the analysis and wrote the manuscript	conducted out most of the analysis and wrote the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5492765	28713416	BA	2	designed the hydrolysis probe assay experiment	designed the hydrolysis probe assay experiment	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5492765	28713416	MB	2	designed the greenhouse experiments	designed the greenhouse experiments	Conceived and designed the experiments	Methodology	YES
4401786	25885433	CH	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401786	25885433	DAN	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401786	25885433	DDS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401786	25885433	DDS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401786	25885433	DDS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401786	25885433	JAL	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401786	25885433	JB	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401786	25885433	JCYL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401786	25885433	JCYL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401786	25885433	JCYL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401786	25885433	JCYL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401786	25885433	JM	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401786	25885433	JML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401786	25885433	JML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401786	25885433	JML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401786	25885433	JML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401786	25885433	MH	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401786	25885433	NFN	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4401786	25885433	NFN	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401786	25885433	PRH	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401786	25885433	PRH	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401786	25885433	RR	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401786	25885433	SFPM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401786	25885433	SFPM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401786	25885433	SFPM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401786	25885433	SG	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401786	25885433	SJU	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401786	25885433	ST	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401786	25885433	TS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401786	25885433	VDL	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401786	25885433	WT	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401786	25885433	YL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5148886	27938326	OR	2	designed the project and wrote the manuscript	designed the project and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5148886	27938326	RS	2	designed the project and wrote the manuscript	designed the project and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5148886	27938326	SW	2	designed the project and wrote the manuscript|carried out data analysis and data interpretation	designed the project and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5148886	27938326	SW	2	designed the project and wrote the manuscript|carried out data analysis and data interpretation	carried out data analysis and data interpretation	Analyzed the data	Formal analysis	YES
3900936	24450933	FF	7	participated in data analysis and drafting first manuscript for this study	participated in data analysis and drafting first manuscript for this study	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3900936	24450933	GL	7	designing of the study, data collection, data analysis and review of manuscript	designing of the study, data collection, data analysis and review of manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Review & Editing	YES
3900936	24450933	GY	7	designed the study, prepared questionnaire, collected data, performed preliminary analysis and wrote the preliminary report for this study	designed the study, prepared questionnaire, collected data, performed preliminary analysis and wrote the preliminary report for this study	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5817830	29417765	Gwyn Gould	7	provided insight and expertise during the study	provided insight and expertise during the study	-	-	NO
5817830	29417765	Margaret Cunningham	7	provided valuable feedback and direction on the experimental work and contributed to the writing of the manuscript	provided valuable feedback and direction on the experimental work and contributed to the writing of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5817830	29417765	Mark Barbour	7	assisted with experimental work and proofread the manuscript	assisted with experimental work and proofread the manuscript	Performed the experiments	Investigation	YES
5817830	29417765	Rachel Wood	7	conceived the project, carried out the majority of the experimental work and wrote the manuscript	conceived the project, carried out the majority of the experimental work and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
5817830	29417765	Robin Plevin	7	conceived the project, provided primary supervision and read over the manuscript	conceived the project, provided primary supervision and read over the manuscript	Conceived and designed the experiments	Conceptualization|Supervision	YES
4306099	25628886	AA	7	Conception and design of study, acquisition and analysis of data, initial draft of the article	Conception and design of study, acquisition and analysis of data, initial draft of the article	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4306099	25628886	AG	7	Interpretation of data, draft and revising article for critical intellectual content	Interpretation of data, draft and revising article for critical intellectual content	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
4306099	25628886	NS	7	Draft and revising article for critical intellectual content	Draft and revising article for critical intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4306099	25628886	QR	7	Interpretation of data, draft and revising article for critical intellectual content	Interpretation of data, draft and revising article for critical intellectual content	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
4306099	25628886	SF	7	Interpretation of data, draft and revising article for critical intellectual content	Interpretation of data, draft and revising article for critical intellectual content	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
4401787	25886365	AS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401787	25886365	AS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401787	25886365	AS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401787	25886365	GKP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401787	25886365	GKP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401787	25886365	GKP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401787	25886365	JB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4401787	25886365	SKJ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
3900937	24450991	CN	2	carried out the study	carried out the study	Performed the experiments	Investigation	YES
3900937	24450991	JA	2	conceived and participated in the design and coordination of the study|carried out the study|analyzed the data and drafted the manuscript with input from all authors	conceived and participated in the design and coordination of the study	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
3900937	24450991	JA	2	conceived and participated in the design and coordination of the study|carried out the study|analyzed the data and drafted the manuscript with input from all authors	carried out the study	Performed the experiments	Investigation	YES
3900937	24450991	JA	2	conceived and participated in the design and coordination of the study|carried out the study|analyzed the data and drafted the manuscript with input from all authors	analyzed the data and drafted the manuscript with input from all authors	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3900937	24450991	JW	2	carried out the study	carried out the study	Performed the experiments	Investigation	YES
3900937	24450991	NNGH	2	coordinated the immunologic testing	coordinated the immunologic testing	Performed the experiments	Investigation|Project administration	YES
3900937	24450991	PB	2	conceived and participated in the design and coordination of the study	conceived and participated in the design and coordination of the study	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
3900937	24450991	PK	2	carried out the study	carried out the study	Performed the experiments	Investigation	YES
3900937	24450991	RH	2	carried out the study	carried out the study	Performed the experiments	Investigation	YES
3900937	24450991	SK	2	carried out the study|analyzed the data and drafted the manuscript with input from all authors	carried out the study	Performed the experiments	Investigation	YES
3900937	24450991	SK	2	carried out the study|analyzed the data and drafted the manuscript with input from all authors	analyzed the data and drafted the manuscript with input from all authors	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3900937	24450991	TA	2	analyzed the data and drafted the manuscript with input from all authors	analyzed the data and drafted the manuscript with input from all authors	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3900937	24450991	TB	2	carried out the study	carried out the study	Performed the experiments	Investigation	YES
3900937	24450991	TJ	2	coordinated the immunologic testing	coordinated the immunologic testing	Performed the experiments	Investigation|Project administration	YES
3900937	24450991	TP	2	conceived and participated in the design and coordination of the study|carried out the study	conceived and participated in the design and coordination of the study	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
3900937	24450991	TP	2	conceived and participated in the design and coordination of the study|carried out the study	carried out the study	Performed the experiments	Investigation	YES
3900937	24450991	WL	2	carried out the study	carried out the study	Performed the experiments	Investigation	YES
3900937	24450991	WTS	2	conceived and participated in the design and coordination of the study	conceived and participated in the design and coordination of the study	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
4323742	25685340	Bengt Anesten	7	data collection, participated in drafting the manuscript	data collection, participated in drafting the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4323742	25685340	Daniel Rydbeck	7	prepared the manuscript, data collection	prepared the manuscript, data collection	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4323742	25685340	Gabriel Sandblom	7	Desgined the study, analysed data, responsible for study design	Desgined the study, analysed data, responsible for study design	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
4323742	25685340	Johanna Osterberg	7	data collection, participated in drafting the manuscript	data collection, participated in drafting the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4323742	25685340	Peter Hajnal	7	data collection, participated in drafting the manuscript	data collection, participated in drafting the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4323742	25685340	Therese Barje	7	data collection, participated in drafting the manuscript	data collection, participated in drafting the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5492850	28713414	All	2	relevant authors and institutions have approved the submission for publication of this manuscript	relevant authors and institutions have approved the submission for publication of this manuscript	-	-	NO
5492850	28713414	EN	2	worked on revising and finalizing the manuscript	worked on revising and finalizing the manuscript	Performed the experiments|Wrote the paper	Writing - Review & Editing	YES
5492850	28713414	JP	2	took care of the whole project, i	took care of the whole project, i	-	-	NO
5492850	28713414	JR	2	were in charge of data collection, analyses, and manuscript drafting and finalizing	were in charge of data collection, analyses, and manuscript drafting and finalizing	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5492850	28713414	XJ	2	were in charge of data collection, analyses, and manuscript drafting and finalizing	were in charge of data collection, analyses, and manuscript drafting and finalizing	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5492850	28713414	XY	2	worked on revising and finalizing the manuscript	worked on revising and finalizing the manuscript	Performed the experiments|Wrote the paper	Writing - Review & Editing	YES
4634745	26629539	APSL	1	Acquisition and molecular characterization of meningococcal isolates|Meningococcal genome sequencing, data analysis and interpretation|Read and approved final manuscript	Acquisition and molecular characterization of meningococcal isolates	Performed the experiments	Investigation	YES
4634745	26629539	APSL	1	Acquisition and molecular characterization of meningococcal isolates|Meningococcal genome sequencing, data analysis and interpretation|Read and approved final manuscript	Meningococcal genome sequencing, data analysis and interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4634745	26629539	APSL	1	Acquisition and molecular characterization of meningococcal isolates|Meningococcal genome sequencing, data analysis and interpretation|Read and approved final manuscript	Read and approved final manuscript	Wrote the paper	Writing - Review & Editing	YES
4634745	26629539	JCDH	1	Meningococcal genome sequencing, data analysis and interpretation|Initial draft and revision of study manuscript|Read and approved final manuscript	Meningococcal genome sequencing, data analysis and interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4634745	26629539	JCDH	1	Meningococcal genome sequencing, data analysis and interpretation|Initial draft and revision of study manuscript|Read and approved final manuscript	Initial draft and revision of study manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4634745	26629539	JCDH	1	Meningococcal genome sequencing, data analysis and interpretation|Initial draft and revision of study manuscript|Read and approved final manuscript	Read and approved final manuscript	Wrote the paper	Writing - Review & Editing	YES
4634745	26629539	JGL	1	Conception of study hypothesis, aims and analytic plans|Meningococcal genome sequencing, data analysis and interpretation|Initial draft and revision of study manuscript|Read and approved final manuscript	Conception of study hypothesis, aims and analytic plans	Conceived and designed the experiments	Conceptualization	YES
4634745	26629539	JGL	1	Conception of study hypothesis, aims and analytic plans|Meningococcal genome sequencing, data analysis and interpretation|Initial draft and revision of study manuscript|Read and approved final manuscript	Meningococcal genome sequencing, data analysis and interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4634745	26629539	JGL	1	Conception of study hypothesis, aims and analytic plans|Meningococcal genome sequencing, data analysis and interpretation|Initial draft and revision of study manuscript|Read and approved final manuscript	Initial draft and revision of study manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4634745	26629539	JGL	1	Conception of study hypothesis, aims and analytic plans|Meningococcal genome sequencing, data analysis and interpretation|Initial draft and revision of study manuscript|Read and approved final manuscript	Read and approved final manuscript	Wrote the paper	Writing - Review & Editing	YES
4634745	26629539	JOF	1	Acquisition and molecular characterization of meningococcal isolates|Meningococcal genome sequencing, data analysis and interpretation|Read and approved final manuscript	Acquisition and molecular characterization of meningococcal isolates	Performed the experiments	Investigation	YES
4634745	26629539	JOF	1	Acquisition and molecular characterization of meningococcal isolates|Meningococcal genome sequencing, data analysis and interpretation|Read and approved final manuscript	Meningococcal genome sequencing, data analysis and interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4634745	26629539	JOF	1	Acquisition and molecular characterization of meningococcal isolates|Meningococcal genome sequencing, data analysis and interpretation|Read and approved final manuscript	Read and approved final manuscript	Wrote the paper	Writing - Review & Editing	YES
4634745	26629539	JWM	1	Conception of study hypothesis, aims and analytic plans|Acquisition and molecular characterization of meningococcal isolates|Meningococcal genome sequencing, data analysis and interpretation|Initial draft and revision of study manuscript|Read and approved final manuscript	Conception of study hypothesis, aims and analytic plans	Conceived and designed the experiments	Conceptualization	YES
4634745	26629539	JWM	1	Conception of study hypothesis, aims and analytic plans|Acquisition and molecular characterization of meningococcal isolates|Meningococcal genome sequencing, data analysis and interpretation|Initial draft and revision of study manuscript|Read and approved final manuscript	Acquisition and molecular characterization of meningococcal isolates	Performed the experiments	Investigation	YES
4634745	26629539	JWM	1	Conception of study hypothesis, aims and analytic plans|Acquisition and molecular characterization of meningococcal isolates|Meningococcal genome sequencing, data analysis and interpretation|Initial draft and revision of study manuscript|Read and approved final manuscript	Meningococcal genome sequencing, data analysis and interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4634745	26629539	JWM	1	Conception of study hypothesis, aims and analytic plans|Acquisition and molecular characterization of meningococcal isolates|Meningococcal genome sequencing, data analysis and interpretation|Initial draft and revision of study manuscript|Read and approved final manuscript	Initial draft and revision of study manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4634745	26629539	JWM	1	Conception of study hypothesis, aims and analytic plans|Acquisition and molecular characterization of meningococcal isolates|Meningococcal genome sequencing, data analysis and interpretation|Initial draft and revision of study manuscript|Read and approved final manuscript	Read and approved final manuscript	Wrote the paper	Writing - Review & Editing	YES
4634745	26629539	LHH	1	Conception of study hypothesis, aims and analytic plans|Acquisition and molecular characterization of meningococcal isolates|Meningococcal genome sequencing, data analysis and interpretation|Initial draft and revision of study manuscript|Read and approved final manuscript	Conception of study hypothesis, aims and analytic plans	Conceived and designed the experiments	Conceptualization	YES
4634745	26629539	LHH	1	Conception of study hypothesis, aims and analytic plans|Acquisition and molecular characterization of meningococcal isolates|Meningococcal genome sequencing, data analysis and interpretation|Initial draft and revision of study manuscript|Read and approved final manuscript	Acquisition and molecular characterization of meningococcal isolates	Performed the experiments	Investigation	YES
4634745	26629539	LHH	1	Conception of study hypothesis, aims and analytic plans|Acquisition and molecular characterization of meningococcal isolates|Meningococcal genome sequencing, data analysis and interpretation|Initial draft and revision of study manuscript|Read and approved final manuscript	Meningococcal genome sequencing, data analysis and interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4634745	26629539	LHH	1	Conception of study hypothesis, aims and analytic plans|Acquisition and molecular characterization of meningococcal isolates|Meningococcal genome sequencing, data analysis and interpretation|Initial draft and revision of study manuscript|Read and approved final manuscript	Initial draft and revision of study manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4634745	26629539	LHH	1	Conception of study hypothesis, aims and analytic plans|Acquisition and molecular characterization of meningococcal isolates|Meningococcal genome sequencing, data analysis and interpretation|Initial draft and revision of study manuscript|Read and approved final manuscript	Read and approved final manuscript	Wrote the paper	Writing - Review & Editing	YES
4634745	26629539	LWM	1	Acquisition and molecular characterization of meningococcal isolates|Meningococcal genome sequencing, data analysis and interpretation|Initial draft and revision of study manuscript|Read and approved final manuscript	Acquisition and molecular characterization of meningococcal isolates	Performed the experiments	Investigation	YES
4634745	26629539	LWM	1	Acquisition and molecular characterization of meningococcal isolates|Meningococcal genome sequencing, data analysis and interpretation|Initial draft and revision of study manuscript|Read and approved final manuscript	Meningococcal genome sequencing, data analysis and interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4634745	26629539	LWM	1	Acquisition and molecular characterization of meningococcal isolates|Meningococcal genome sequencing, data analysis and interpretation|Initial draft and revision of study manuscript|Read and approved final manuscript	Initial draft and revision of study manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4634745	26629539	LWM	1	Acquisition and molecular characterization of meningococcal isolates|Meningococcal genome sequencing, data analysis and interpretation|Initial draft and revision of study manuscript|Read and approved final manuscript	Read and approved final manuscript	Wrote the paper	Writing - Review & Editing	YES
4634745	26629539	MGK	1	Meningococcal genome sequencing, data analysis and interpretation|Initial draft and revision of study manuscript|Read and approved final manuscript	Meningococcal genome sequencing, data analysis and interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4634745	26629539	MGK	1	Meningococcal genome sequencing, data analysis and interpretation|Initial draft and revision of study manuscript|Read and approved final manuscript	Initial draft and revision of study manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4634745	26629539	MGK	1	Meningococcal genome sequencing, data analysis and interpretation|Initial draft and revision of study manuscript|Read and approved final manuscript	Read and approved final manuscript	Wrote the paper	Writing - Review & Editing	YES
4634745	26629539	MMM	1	Conception of study hypothesis, aims and analytic plans|Meningococcal genome sequencing, data analysis and interpretation|Initial draft and revision of study manuscript|Read and approved final manuscript	Conception of study hypothesis, aims and analytic plans	Conceived and designed the experiments	Conceptualization	YES
4634745	26629539	MMM	1	Conception of study hypothesis, aims and analytic plans|Meningococcal genome sequencing, data analysis and interpretation|Initial draft and revision of study manuscript|Read and approved final manuscript	Meningococcal genome sequencing, data analysis and interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4634745	26629539	MMM	1	Conception of study hypothesis, aims and analytic plans|Meningococcal genome sequencing, data analysis and interpretation|Initial draft and revision of study manuscript|Read and approved final manuscript	Initial draft and revision of study manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4634745	26629539	MMM	1	Conception of study hypothesis, aims and analytic plans|Meningococcal genome sequencing, data analysis and interpretation|Initial draft and revision of study manuscript|Read and approved final manuscript	Read and approved final manuscript	Wrote the paper	Writing - Review & Editing	YES
4634745	26629539	NLH	1	Conception of study hypothesis, aims and analytic plans|Meningococcal genome sequencing, data analysis and interpretation|Initial draft and revision of study manuscript|Read and approved final manuscript	Conception of study hypothesis, aims and analytic plans	Conceived and designed the experiments	Conceptualization	YES
4634745	26629539	NLH	1	Conception of study hypothesis, aims and analytic plans|Meningococcal genome sequencing, data analysis and interpretation|Initial draft and revision of study manuscript|Read and approved final manuscript	Meningococcal genome sequencing, data analysis and interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4634745	26629539	NLH	1	Conception of study hypothesis, aims and analytic plans|Meningococcal genome sequencing, data analysis and interpretation|Initial draft and revision of study manuscript|Read and approved final manuscript	Initial draft and revision of study manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4634745	26629539	NLH	1	Conception of study hypothesis, aims and analytic plans|Meningococcal genome sequencing, data analysis and interpretation|Initial draft and revision of study manuscript|Read and approved final manuscript	Read and approved final manuscript	Wrote the paper	Writing - Review & Editing	YES
4634745	26629539	XW	1	Acquisition and molecular characterization of meningococcal isolates|Meningococcal genome sequencing, data analysis and interpretation|Initial draft and revision of study manuscript|Read and approved final manuscript	Acquisition and molecular characterization of meningococcal isolates	Performed the experiments	Investigation	YES
4634745	26629539	XW	1	Acquisition and molecular characterization of meningococcal isolates|Meningococcal genome sequencing, data analysis and interpretation|Initial draft and revision of study manuscript|Read and approved final manuscript	Meningococcal genome sequencing, data analysis and interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4634745	26629539	XW	1	Acquisition and molecular characterization of meningococcal isolates|Meningococcal genome sequencing, data analysis and interpretation|Initial draft and revision of study manuscript|Read and approved final manuscript	Initial draft and revision of study manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4634745	26629539	XW	1	Acquisition and molecular characterization of meningococcal isolates|Meningococcal genome sequencing, data analysis and interpretation|Initial draft and revision of study manuscript|Read and approved final manuscript	Read and approved final manuscript	Wrote the paper	Writing - Review & Editing	YES
3902420	24447375	CG	2	reviewed and interpreted the data and edited the manuscript	reviewed and interpreted the data and edited the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
3902420	24447375	CH	2	reviewed all the radiological images	reviewed all the radiological images	Analyzed the data	Visualization	YES
3902420	24447375	DN	2	reviewed all the pathology and wrote the reports	reviewed all the pathology and wrote the reports	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3902420	24447375	IL	2	were the primary care physicians of the patients, analyzed and interpreted the data	were the primary care physicians of the patients, analyzed and interpreted the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3902420	24447375	JB	2	treated the oncology patient and interpreted the data	treated the oncology patient and interpreted the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3902420	24447375	MH	2	performed the surgical procedures or were part of the decision-making process	performed the surgical procedures or were part of the decision-making process	Performed the experiments	Investigation	YES
3902420	24447375	RS	2	performed the surgical procedures or were part of the decision-making process	performed the surgical procedures or were part of the decision-making process	Performed the experiments	Investigation	YES
3902420	24447375	VL	2	were the primary care physicians of the patients, analyzed and interpreted the data	were the primary care physicians of the patients, analyzed and interpreted the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3902420	24447375	ZRC	2	conducted the study, interpreted the data, and edited the manuscript|performed the surgical procedures or were part of the decision-making process	conducted the study, interpreted the data, and edited the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
3902420	24447375	ZRC	2	conducted the study, interpreted the data, and edited the manuscript|performed the surgical procedures or were part of the decision-making process	performed the surgical procedures or were part of the decision-making process	Performed the experiments	Investigation	YES
3902420	24447375	ZZ	2	conducted the study, interpreted the data, and edited the manuscript|performed the surgical procedures or were part of the decision-making process	conducted the study, interpreted the data, and edited the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
3902420	24447375	ZZ	2	conducted the study, interpreted the data, and edited the manuscript|performed the surgical procedures or were part of the decision-making process	performed the surgical procedures or were part of the decision-making process	Performed the experiments	Investigation	YES
4401790	25886375	ALP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Designed the study protocol|Performed the statistical analysis|Analyzed and interpreted the results|Drafted the manuscript|Reviewed and approved the final manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401790	25886375	ALP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Designed the study protocol|Performed the statistical analysis|Analyzed and interpreted the results|Drafted the manuscript|Reviewed and approved the final manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4401790	25886375	ALP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Designed the study protocol|Performed the statistical analysis|Analyzed and interpreted the results|Drafted the manuscript|Reviewed and approved the final manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401790	25886375	ALP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Designed the study protocol|Performed the statistical analysis|Analyzed and interpreted the results|Drafted the manuscript|Reviewed and approved the final manuscript	Designed the study protocol	Conceived and designed the experiments	Methodology	YES
4401790	25886375	ALP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Designed the study protocol|Performed the statistical analysis|Analyzed and interpreted the results|Drafted the manuscript|Reviewed and approved the final manuscript	Performed the statistical analysis	Analyzed the data	Formal analysis	YES
4401790	25886375	ALP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Designed the study protocol|Performed the statistical analysis|Analyzed and interpreted the results|Drafted the manuscript|Reviewed and approved the final manuscript	Analyzed and interpreted the results	Analyzed the data	Formal analysis	YES
4401790	25886375	ALP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Designed the study protocol|Performed the statistical analysis|Analyzed and interpreted the results|Drafted the manuscript|Reviewed and approved the final manuscript	Drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4401790	25886375	ALP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Designed the study protocol|Performed the statistical analysis|Analyzed and interpreted the results|Drafted the manuscript|Reviewed and approved the final manuscript	Reviewed and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4401790	25886375	AM	PLoS5	Performed the experiments|Wrote the paper|Carried out the test evaluation|Reviewed and approved the final manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4401790	25886375	AM	PLoS5	Performed the experiments|Wrote the paper|Carried out the test evaluation|Reviewed and approved the final manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401790	25886375	AM	PLoS5	Performed the experiments|Wrote the paper|Carried out the test evaluation|Reviewed and approved the final manuscript	Carried out the test evaluation	Performed the experiments	Investigation	YES
4401790	25886375	AM	PLoS5	Performed the experiments|Wrote the paper|Carried out the test evaluation|Reviewed and approved the final manuscript	Reviewed and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4401790	25886375	CSK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the study protocol|Analyzed and interpreted the results|Drafted the manuscript|Reviewed and approved the final manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401790	25886375	CSK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the study protocol|Analyzed and interpreted the results|Drafted the manuscript|Reviewed and approved the final manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4401790	25886375	CSK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the study protocol|Analyzed and interpreted the results|Drafted the manuscript|Reviewed and approved the final manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401790	25886375	CSK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the study protocol|Analyzed and interpreted the results|Drafted the manuscript|Reviewed and approved the final manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401790	25886375	CSK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the study protocol|Analyzed and interpreted the results|Drafted the manuscript|Reviewed and approved the final manuscript	Designed the study protocol	Conceived and designed the experiments	Methodology	YES
4401790	25886375	CSK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the study protocol|Analyzed and interpreted the results|Drafted the manuscript|Reviewed and approved the final manuscript	Analyzed and interpreted the results	Analyzed the data	Formal analysis	YES
4401790	25886375	CSK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the study protocol|Analyzed and interpreted the results|Drafted the manuscript|Reviewed and approved the final manuscript	Drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4401790	25886375	CSK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the study protocol|Analyzed and interpreted the results|Drafted the manuscript|Reviewed and approved the final manuscript	Reviewed and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4401790	25886375	KB	PLoS5	Performed the experiments|Wrote the paper|Carried out the test evaluation|Reviewed and approved the final manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4401790	25886375	KB	PLoS5	Performed the experiments|Wrote the paper|Carried out the test evaluation|Reviewed and approved the final manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401790	25886375	KB	PLoS5	Performed the experiments|Wrote the paper|Carried out the test evaluation|Reviewed and approved the final manuscript	Carried out the test evaluation	Performed the experiments	Investigation	YES
4401790	25886375	KB	PLoS5	Performed the experiments|Wrote the paper|Carried out the test evaluation|Reviewed and approved the final manuscript	Reviewed and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4401790	25886375	WDK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the study protocol|Organized the sample collection|Performed the statistical analysis|Analyzed and interpreted the results|Drafted the manuscript|Reviewed and approved the final manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401790	25886375	WDK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the study protocol|Organized the sample collection|Performed the statistical analysis|Analyzed and interpreted the results|Drafted the manuscript|Reviewed and approved the final manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4401790	25886375	WDK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the study protocol|Organized the sample collection|Performed the statistical analysis|Analyzed and interpreted the results|Drafted the manuscript|Reviewed and approved the final manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4401790	25886375	WDK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the study protocol|Organized the sample collection|Performed the statistical analysis|Analyzed and interpreted the results|Drafted the manuscript|Reviewed and approved the final manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401790	25886375	WDK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the study protocol|Organized the sample collection|Performed the statistical analysis|Analyzed and interpreted the results|Drafted the manuscript|Reviewed and approved the final manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401790	25886375	WDK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the study protocol|Organized the sample collection|Performed the statistical analysis|Analyzed and interpreted the results|Drafted the manuscript|Reviewed and approved the final manuscript	Designed the study protocol	Conceived and designed the experiments	Methodology	YES
4401790	25886375	WDK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the study protocol|Organized the sample collection|Performed the statistical analysis|Analyzed and interpreted the results|Drafted the manuscript|Reviewed and approved the final manuscript	Organized the sample collection	Performed the experiments	Investigation	YES
4401790	25886375	WDK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the study protocol|Organized the sample collection|Performed the statistical analysis|Analyzed and interpreted the results|Drafted the manuscript|Reviewed and approved the final manuscript	Performed the statistical analysis	Analyzed the data	Formal analysis	YES
4401790	25886375	WDK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the study protocol|Organized the sample collection|Performed the statistical analysis|Analyzed and interpreted the results|Drafted the manuscript|Reviewed and approved the final manuscript	Analyzed and interpreted the results	Analyzed the data	Formal analysis	YES
4401790	25886375	WDK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the study protocol|Organized the sample collection|Performed the statistical analysis|Analyzed and interpreted the results|Drafted the manuscript|Reviewed and approved the final manuscript	Drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4401790	25886375	WDK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the study protocol|Organized the sample collection|Performed the statistical analysis|Analyzed and interpreted the results|Drafted the manuscript|Reviewed and approved the final manuscript	Reviewed and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
514892	15285787	ANZ	2	carried out the bioinformatics studies and participated in the interpretation of its results	carried out the bioinformatics studies and participated in the interpretation of its results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
514892	15285787	Both authors	2	participated in writing the manuscript and approved its final form	participated in writing the manuscript and approved its final form	Wrote the paper	Writing - Original Draft	YES
514892	15285787	JEG	2	conceived the study and participated in the interpretation of its results	conceived the study and participated in the interpretation of its results	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
4555362	24913311	Bing Lu	PLoS52	collected the clinical samples, including the patients information, performed the experiments, and analyzed the data|wrote the article	collected the clinical samples, including the patients information, performed the experiments, and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4555362	24913311	Bing Lu	PLoS52	collected the clinical samples, including the patients information, performed the experiments, and analyzed the data|wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
4555362	24913311	Cha-Xiang Guan	PLoS52	conceived and designed the experiments|contributed reagents, materials, and analysis tools|wrote the article	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4555362	24913311	Cha-Xiang Guan	PLoS52	conceived and designed the experiments|contributed reagents, materials, and analysis tools|wrote the article	contributed reagents, materials, and analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4555362	24913311	Cha-Xiang Guan	PLoS52	conceived and designed the experiments|contributed reagents, materials, and analysis tools|wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
4555362	24913311	Charles Pan Jiao	PLoS52	collected the clinical samples, including the patients information, performed the experiments, and analyzed the data	collected the clinical samples, including the patients information, performed the experiments, and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4555362	24913311	Kanglin Wan	PLoS52	conceived and designed the experiments|contributed reagents, materials, and analysis tools|wrote the article	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4555362	24913311	Kanglin Wan	PLoS52	conceived and designed the experiments|contributed reagents, materials, and analysis tools|wrote the article	contributed reagents, materials, and analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4555362	24913311	Kanglin Wan	PLoS52	conceived and designed the experiments|contributed reagents, materials, and analysis tools|wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
4555362	24913311	Li Wan	PLoS52	collected the clinical samples, including the patients information, performed the experiments, and analyzed the data	collected the clinical samples, including the patients information, performed the experiments, and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4555362	24913311	Tongyang Xiao	PLoS52	collected the clinical samples, including the patients information, performed the experiments, and analyzed the data	collected the clinical samples, including the patients information, performed the experiments, and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4555362	24913311	Yansen Wang	PLoS52	collected the clinical samples, including the patients information, performed the experiments, and analyzed the data|wrote the article	collected the clinical samples, including the patients information, performed the experiments, and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4555362	24913311	Yansen Wang	PLoS52	collected the clinical samples, including the patients information, performed the experiments, and analyzed the data|wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
3438735	22973171	All authors	2	have participated and contributed in this paper	have participated and contributed in this paper	-	-	NO
3904465	24373482	AF	2	participated in drafting and improving manuscript	participated in drafting and improving manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3904465	24373482	CL	2	was responsible for study design, data interpretation and manuscript writing	was responsible for study design, data interpretation and manuscript writing	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3904465	24373482	CW	2	participated in study design and statistical analysis	participated in study design and statistical analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
3904465	24373482	GD	2	participated in drafting and improving manuscript	participated in drafting and improving manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3904465	24373482	HM	2	participated in drafting and improving manuscript	participated in drafting and improving manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3904465	24373482	MJG	2	participated in drafting and improving manuscript	participated in drafting and improving manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3904465	24373482	MY	2	participated in study design, coordination and drafting the manuscript	participated in study design, coordination and drafting the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft	YES
3904465	24373482	RK	2	participated in drafting and improving manuscript	participated in drafting and improving manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3904465	24373482	TM	2	participated in drafting and improving manuscript	participated in drafting and improving manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5821896	29484189	DB	2	analyzed and interpreted the data|drafted the manuscript|helped with the critical revision of the manuscript for important intellectual content	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5821896	29484189	DB	2	analyzed and interpreted the data|drafted the manuscript|helped with the critical revision of the manuscript for important intellectual content	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5821896	29484189	DB	2	analyzed and interpreted the data|drafted the manuscript|helped with the critical revision of the manuscript for important intellectual content	helped with the critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5821896	29484189	FPM	2	helped with the study concept and design|analyzed and interpreted the data|drafted the manuscript|helped with the critical revision of the manuscript for important intellectual content	helped with the study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5821896	29484189	FPM	2	helped with the study concept and design|analyzed and interpreted the data|drafted the manuscript|helped with the critical revision of the manuscript for important intellectual content	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5821896	29484189	FPM	2	helped with the study concept and design|analyzed and interpreted the data|drafted the manuscript|helped with the critical revision of the manuscript for important intellectual content	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5821896	29484189	FPM	2	helped with the study concept and design|analyzed and interpreted the data|drafted the manuscript|helped with the critical revision of the manuscript for important intellectual content	helped with the critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5821896	29484189	JK	2	helped with the study concept and design|helped in the acquisition of data	helped with the study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5821896	29484189	JK	2	helped with the study concept and design|helped in the acquisition of data	helped in the acquisition of data	Performed the experiments	Investigation	YES
5821896	29484189	JNB	2	helped with the study concept and design|helped in the acquisition of data|analyzed and interpreted the data|drafted the manuscript|helped with the critical revision of the manuscript for important intellectual content	helped with the study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5821896	29484189	JNB	2	helped with the study concept and design|helped in the acquisition of data|analyzed and interpreted the data|drafted the manuscript|helped with the critical revision of the manuscript for important intellectual content	helped in the acquisition of data	Performed the experiments	Investigation	YES
5821896	29484189	JNB	2	helped with the study concept and design|helped in the acquisition of data|analyzed and interpreted the data|drafted the manuscript|helped with the critical revision of the manuscript for important intellectual content	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5821896	29484189	JNB	2	helped with the study concept and design|helped in the acquisition of data|analyzed and interpreted the data|drafted the manuscript|helped with the critical revision of the manuscript for important intellectual content	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5821896	29484189	JNB	2	helped with the study concept and design|helped in the acquisition of data|analyzed and interpreted the data|drafted the manuscript|helped with the critical revision of the manuscript for important intellectual content	helped with the critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5821896	29484189	JRP	2	helped with the critical revision of the manuscript for important intellectual content|helped with the study supervision	helped with the critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5821896	29484189	JRP	2	helped with the critical revision of the manuscript for important intellectual content|helped with the study supervision	helped with the study supervision	-	Supervision	YES
5821896	29484189	RD	2	helped in the acquisition of data	helped in the acquisition of data	Performed the experiments	Investigation	YES
5821896	29484189	SH	2	helped with the critical revision of the manuscript for important intellectual content	helped with the critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5821896	29484189	SJ	2	helped in the acquisition of data	helped in the acquisition of data	Performed the experiments	Investigation	YES
5821896	29484189	TSD	2	helped with the study concept and design|helped in the acquisition of data|analyzed and interpreted the data|helped with the critical revision of the manuscript for important intellectual content|performed the statistical analysis	helped with the study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5821896	29484189	TSD	2	helped with the study concept and design|helped in the acquisition of data|analyzed and interpreted the data|helped with the critical revision of the manuscript for important intellectual content|performed the statistical analysis	helped in the acquisition of data	Performed the experiments	Investigation	YES
5821896	29484189	TSD	2	helped with the study concept and design|helped in the acquisition of data|analyzed and interpreted the data|helped with the critical revision of the manuscript for important intellectual content|performed the statistical analysis	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5821896	29484189	TSD	2	helped with the study concept and design|helped in the acquisition of data|analyzed and interpreted the data|helped with the critical revision of the manuscript for important intellectual content|performed the statistical analysis	helped with the critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5821896	29484189	TSD	2	helped with the study concept and design|helped in the acquisition of data|analyzed and interpreted the data|helped with the critical revision of the manuscript for important intellectual content|performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
5821896	29484189	VD	2	helped in the acquisition of data	helped in the acquisition of data	Performed the experiments	Investigation	YES
5492853	28713402	All authors	2	gave final approval for publication	gave final approval for publication	-	-	NO
5492853	28713402	CZ	2	conducted the literature survey and drafted the article	conducted the literature survey and drafted the article	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5492853	28713402	GY	2	conducted the literature survey and drafted the article	conducted the literature survey and drafted the article	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5492853	28713402	HL	2	gave valuable comments to the manuscript and carried out critical revisions	gave valuable comments to the manuscript and carried out critical revisions	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5492853	28713402	HY	2	gave valuable comments to the manuscript and carried out critical revisions	gave valuable comments to the manuscript and carried out critical revisions	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5492853	28713402	HYang	2	gave valuable comments to the manuscript and carried out critical revisions	gave valuable comments to the manuscript and carried out critical revisions	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5492853	28713402	JL	2	conducted the literature survey and drafted the article	conducted the literature survey and drafted the article	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5492853	28713402	Zhenhai Li	2	gave valuable comments to the manuscript and carried out critical revisions	gave valuable comments to the manuscript and carried out critical revisions	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5492853	28713402	Zhenhong Li	2	gave valuable comments to the manuscript and carried out critical revisions	gave valuable comments to the manuscript and carried out critical revisions	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
3922541	24506969	BTS	2	conceived the case report, did the literature research and drafted the manuscript	conceived the case report, did the literature research and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
3922541	24506969	MWP	2	helped to draft the manuscript and participated in the literature research and coordination	helped to draft the manuscript and participated in the literature research and coordination	Wrote the paper	Formal analysis|Project administration|Writing - Original Draft	YES
5842406	29541476	E. Shinozawa	2	designed and performed the experiments, analyzed and interpreted data, and wrote the manuscript	designed and performed the experiments, analyzed and interpreted data, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5842406	29541476	H. Yamakawa	2	designed and performed the experiments, and analyzed and interpreted data	designed and performed the experiments, and analyzed and interpreted data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5842406	29541476	M. Haba	2	designed and performed the experiments, and analyzed and interpreted data	designed and performed the experiments, and analyzed and interpreted data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5842406	29541476	M. Shimada	2	prepared the compound and supervised the study	prepared the compound and supervised the study	Performed the experiments	Investigation|Supervision	YES
5842406	29541476	R. Tozawa	2	supervised the study and wrote the manuscript	supervised the study and wrote the manuscript	Wrote the paper	Supervision|Writing - Original Draft	YES
5842406	29541476	Y. Amano	2	designed and performed the experiments, analyzed and interpreted data, and wrote the manuscript	designed and performed the experiments, analyzed and interpreted data, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4323753	25685344	GM	7	surgery, manuscript review	surgery, manuscript review	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4323753	25685344	SU	7	surgery, data collection, manuscript writing and review	surgery, data collection, manuscript writing and review	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
4323753	25685344	VB	7	surgery, manuscript review	surgery, manuscript review	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5148921	27938339	CLSJ	2	designed the experiment and provided molecular data	designed the experiment and provided molecular data	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources	YES
3922732	24456757	ASH	2	coordinated the data/sample collection, analyzed the data and prepared the draft manuscript	coordinated the data/sample collection, analyzed the data and prepared the draft manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Project administration|Writing - Original Draft	YES
3922732	24456757	All authors	2	reviewed and approved the final manuscript	reviewed and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
3922732	24456757	CAO	2	assisted with the coordination of the data and sample collection	assisted with the coordination of the data and sample collection	Performed the experiments	Investigation|Project administration	YES
3922732	24456757	ES	2	provided guidance and mentorship during the implementation of the study	provided guidance and mentorship during the implementation of the study	Performed the experiments	Investigation|Supervision	YES
3922732	24456757	HN	2	assisted with the coordination of the data and sample collection	assisted with the coordination of the data and sample collection	Performed the experiments	Investigation|Project administration	YES
3922732	24456757	JAB	2	conceived the study|provided guidance and mentorship during the implementation of the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
3922732	24456757	JAB	2	conceived the study|provided guidance and mentorship during the implementation of the study	provided guidance and mentorship during the implementation of the study	Performed the experiments	Investigation|Supervision	YES
3922732	24456757	PAC	2	conceived the study|provided guidance and mentorship during the implementation of the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
3922732	24456757	PAC	2	conceived the study|provided guidance and mentorship during the implementation of the study	provided guidance and mentorship during the implementation of the study	Performed the experiments	Investigation|Supervision	YES
3922732	24456757	SM	2	assisted with the coordination of the data and sample collection	assisted with the coordination of the data and sample collection	Performed the experiments	Investigation|Project administration	YES
3922732	24456757	TFRW	2	provided guidance and mentorship during the implementation of the study	provided guidance and mentorship during the implementation of the study	Performed the experiments	Investigation|Supervision	YES
4703710	26844283	BS	2	collected data for analysis and interpretation	collected data for analysis and interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4703710	26844283	CL	2	were for data interpretation, administrative, technical, or material support	were for data interpretation, administrative, technical, or material support	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Project administration	YES
4703710	26844283	ED	2	designed the trial and analyzed the data|collected data for analysis and interpretation	designed the trial and analyzed the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
4703710	26844283	ED	2	designed the trial and analyzed the data|collected data for analysis and interpretation	collected data for analysis and interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4703710	26844283	EG	2	were for data interpretation, administrative, technical, or material support	were for data interpretation, administrative, technical, or material support	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Project administration	YES
4703710	26844283	EM	2	were for data interpretation, administrative, technical, or material support	were for data interpretation, administrative, technical, or material support	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Project administration	YES
4703710	26844283	EMR	2	were for data interpretation, administrative, technical, or material support	were for data interpretation, administrative, technical, or material support	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Project administration	YES
4703710	26844283	HW	2	were for data interpretation, administrative, technical, or material support	were for data interpretation, administrative, technical, or material support	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Project administration	YES
4703710	26844283	HZ	2	were for data interpretation, administrative, technical, or material support	were for data interpretation, administrative, technical, or material support	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Project administration	YES
4703710	26844283	JG	2	were for data interpretation, administrative, technical, or material support	were for data interpretation, administrative, technical, or material support	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Project administration	YES
4703710	26844283	JO	2	designed the trial and analyzed the data|obtained the funding	designed the trial and analyzed the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
4703710	26844283	JO	2	designed the trial and analyzed the data|obtained the funding	obtained the funding	-	Funding acquisition	YES
4703710	26844283	MA	2	were for data interpretation, administrative, technical, or material support	were for data interpretation, administrative, technical, or material support	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Project administration	YES
4703710	26844283	MP	2	collected data for analysis and interpretation	collected data for analysis and interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4703710	26844283	RT	2	were for data interpretation, administrative, technical, or material support	were for data interpretation, administrative, technical, or material support	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Project administration	YES
4703710	26844283	SP	2	were for data interpretation, administrative, technical, or material support	were for data interpretation, administrative, technical, or material support	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Project administration	YES
4703710	26844283	TM	2	were for data interpretation, administrative, technical, or material support	were for data interpretation, administrative, technical, or material support	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Project administration	YES
4703710	26844283	YZ	2	designed the trial and analyzed the data|drafted the manuscript|obtained the funding|collected data for analysis and interpretation	designed the trial and analyzed the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
4703710	26844283	YZ	2	designed the trial and analyzed the data|drafted the manuscript|obtained the funding|collected data for analysis and interpretation	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4703710	26844283	YZ	2	designed the trial and analyzed the data|drafted the manuscript|obtained the funding|collected data for analysis and interpretation	obtained the funding	-	Funding acquisition	YES
4703710	26844283	YZ	2	designed the trial and analyzed the data|drafted the manuscript|obtained the funding|collected data for analysis and interpretation	collected data for analysis and interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4703710	26844283	ZZ	2	were for data interpretation, administrative, technical, or material support	were for data interpretation, administrative, technical, or material support	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Project administration	YES
5492869	28713419	CV-M	2	analyzed the data and reviewed drafts of the paper	analyzed the data and reviewed drafts of the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5492869	28713419	YS	2	conceived and designed the experiments, performed the experiments, analyzed the data, and wrote the paper	conceived and designed the experiments, performed the experiments, analyzed the data, and wrote the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4401794	25886011	BC	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401794	25886011	JH	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401794	25886011	JP	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401794	25886011	LZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401794	25886011	LZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401794	25886011	LZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401794	25886011	LZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401794	25886011	MF	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401794	25886011	PH	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4401794	25886011	XA	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4401794	25886011	XA	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4401794	25886011	YS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4401794	25886011	YS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4401794	25886011	YS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4401794	25886011	YS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4401794	25886011	ZZ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
3922737	24444369	All authors	2	contributed to the editing and production of the final manuscript	contributed to the editing and production of the final manuscript	Wrote the paper	Writing - Review & Editing	YES
3922737	24444369	JM	2	carried out the laboratory assays|performed sequence analysis	carried out the laboratory assays	Performed the experiments	Investigation	YES
3922737	24444369	JM	2	carried out the laboratory assays|performed sequence analysis	performed sequence analysis	Performed the experiments	Investigation	YES
3922737	24444369	RJL	2	formulated the design and coordinated the study	formulated the design and coordinated the study	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
3922737	24444369	RMB	2	formulated the design and coordinated the study	formulated the design and coordinated the study	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
3922737	24444369	SD	2	performed sequence analysis|performed the statistical analysis|produced the first draft of the manuscript|formulated the design and coordinated the study	performed sequence analysis	Performed the experiments	Investigation	YES
3922737	24444369	SD	2	performed sequence analysis|performed the statistical analysis|produced the first draft of the manuscript|formulated the design and coordinated the study	performed the statistical analysis	Analyzed the data	Formal analysis	YES
3922737	24444369	SD	2	performed sequence analysis|performed the statistical analysis|produced the first draft of the manuscript|formulated the design and coordinated the study	produced the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
3922737	24444369	SD	2	performed sequence analysis|performed the statistical analysis|produced the first draft of the manuscript|formulated the design and coordinated the study	formulated the design and coordinated the study	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
3922737	24444369	SP	2	carried out the laboratory assays|produced the first draft of the manuscript	carried out the laboratory assays	Performed the experiments	Investigation	YES
3922737	24444369	SP	2	carried out the laboratory assays|produced the first draft of the manuscript	produced the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
3922737	24444369	TdO	2	formulated the design and coordinated the study	formulated the design and coordinated the study	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
4452292	26090462	Baojun Wang	PLoS52	are the co-first authors|performed the experiments	are the co-first authors	-	-	NO
4452292	26090462	Baojun Wang	PLoS52	are the co-first authors|performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
4452292	26090462	Dazhuo Shi	PLoS52	conceived and designed the animal experiments and helped to draft the paper	conceived and designed the animal experiments and helped to draft the paper	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Writing - Original Draft	YES
4452292	26090462	Jiangang Liu	PLoS52	conceived and designed the animal experiments and helped to draft the paper	conceived and designed the animal experiments and helped to draft the paper	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Writing - Original Draft	YES
4452292	26090462	Lei Zhang	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
4452292	26090462	Qingxiang Zhang	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
4452292	26090462	Yue Liu	PLoS52	are the co-first authors	are the co-first authors	-	-	NO
4323756	25685339	Saran Shantikumar	2	study concept and design, data collection, analysis, interpretation, critical revision of manuscript	study concept and design, data collection, analysis, interpretation, critical revision of manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Review & Editing	YES
4323756	25685339	Waseem Hameed	2	study design, interpretation, critical revision of manuscript	study design, interpretation, critical revision of manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
515299	15310403	ALH	2	carried out the phylogenetic and molecular evolutionary analyses	carried out the phylogenetic and molecular evolutionary analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
515299	15310403	DSN	2	participated in tissue collection and preparation	participated in tissue collection and preparation	-	-	NO
515299	15310403	GZ	2	conceived of the study, carried out all computational analyses and annotation, drafted the manuscript, and participated in its design and coordination	conceived of the study, carried out all computational analyses and annotation, drafted the manuscript, and participated in its design and coordination	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Data curation|Formal analysis|Investigation|Methodology|Project administration|Writing - Original Draft	YES
515299	15310403	JA	2	carried out the fluorescence in situ hybridization	carried out the fluorescence in situ hybridization	Performed the experiments	Investigation	YES
515299	15310403	YM	2	carried out the fluorescence in situ hybridization	carried out the fluorescence in situ hybridization	Performed the experiments	Investigation	YES
515299	15310403	YX	2	carried out the tissue collection, rt pcr analysis of tissue expression patterns, and drafted the manuscript	carried out the tissue collection, rt pcr analysis of tissue expression patterns, and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3922739	24460764	ACW	2	assisted with study design, data interpretation, and editing the manuscript	assisted with study design, data interpretation, and editing the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
3922739	24460764	AG	2	assisted with study design, data interpretation, and editing the manuscript	assisted with study design, data interpretation, and editing the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
3922739	24460764	BKA	2	designed and conducted the study, interpreted the data, and prepared and edited the manuscript	designed and conducted the study, interpreted the data, and prepared and edited the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
3922739	24460764	ENJ	2	designed and conducted the study, interpreted the data, and prepared and edited the manuscript	designed and conducted the study, interpreted the data, and prepared and edited the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
3922739	24460764	GEM	2	assisted with study design, data interpretation, and editing the manuscript	assisted with study design, data interpretation, and editing the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
3922739	24460764	JFO	2	assisted with study design, data interpretation, and editing the manuscript	assisted with study design, data interpretation, and editing the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
3922739	24460764	MLL	2	assisted with study design, data interpretation, and editing the manuscript	assisted with study design, data interpretation, and editing the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
3922739	24460764	MPR	2	designed and conducted the study, interpreted the data, and prepared and edited the manuscript	designed and conducted the study, interpreted the data, and prepared and edited the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
3922739	24460764	NFC	2	assisted with study design, data interpretation, and editing the manuscript	assisted with study design, data interpretation, and editing the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
4703725	26844287	A.F.	2	assisted with bioinformatic work	assisted with bioinformatic work	-	Formal analysis	YES
4703725	26844287	A.J.P.	2	conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4703725	26844287	D.F.K.	2	conceived the study|interpreted data	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4703725	26844287	D.F.K.	2	conceived the study|interpreted data	interpreted data	Analyzed the data	Formal analysis	YES
4703725	26844287	E.A.C.	2	conceived the study|collected data	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4703725	26844287	E.A.C.	2	conceived the study|collected data	collected data	Performed the experiments	Investigation	YES
4703725	26844287	G.L.	2	assisted with bioinformatic work	assisted with bioinformatic work	-	Formal analysis	YES
4703725	26844287	J.D.G.	2	conceived the study|performed data analysis|wrote the manuscript, with input from all authors	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4703725	26844287	J.D.G.	2	conceived the study|performed data analysis|wrote the manuscript, with input from all authors	performed data analysis	Analyzed the data	Formal analysis	YES
4703725	26844287	J.D.G.	2	conceived the study|performed data analysis|wrote the manuscript, with input from all authors	wrote the manuscript, with input from all authors	Wrote the paper	Writing - Original Draft	YES
4703725	26844287	J.T.	2	conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4703725	26844287	M.M.	2	assisted with bioinformatic work	assisted with bioinformatic work	-	Formal analysis	YES
4703725	26844287	R.V.D.M.	2	conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4703725	26844287	V.C.	2	conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5494288	28717360	AM	PLoS52	designed the study|conducted the experiments|analyzed the data|reviewed the data and wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5494288	28717360	AM	PLoS52	designed the study|conducted the experiments|analyzed the data|reviewed the data and wrote the manuscript	conducted the experiments	Performed the experiments	Investigation	YES
5494288	28717360	AM	PLoS52	designed the study|conducted the experiments|analyzed the data|reviewed the data and wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5494288	28717360	AM	PLoS52	designed the study|conducted the experiments|analyzed the data|reviewed the data and wrote the manuscript	reviewed the data and wrote the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5494288	28717360	CH	PLoS52	conducted the experiments	conducted the experiments	Performed the experiments	Investigation	YES
5494288	28717360	HN	PLoS52	designed the study|conducted the experiments|analyzed the data|reviewed the data and wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5494288	28717360	HN	PLoS52	designed the study|conducted the experiments|analyzed the data|reviewed the data and wrote the manuscript	conducted the experiments	Performed the experiments	Investigation	YES
5494288	28717360	HN	PLoS52	designed the study|conducted the experiments|analyzed the data|reviewed the data and wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5494288	28717360	HN	PLoS52	designed the study|conducted the experiments|analyzed the data|reviewed the data and wrote the manuscript	reviewed the data and wrote the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5494288	28717360	KS	PLoS52	designed the study|conducted the experiments|analyzed the data|reviewed the data and wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5494288	28717360	KS	PLoS52	designed the study|conducted the experiments|analyzed the data|reviewed the data and wrote the manuscript	conducted the experiments	Performed the experiments	Investigation	YES
5494288	28717360	KS	PLoS52	designed the study|conducted the experiments|analyzed the data|reviewed the data and wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5494288	28717360	KS	PLoS52	designed the study|conducted the experiments|analyzed the data|reviewed the data and wrote the manuscript	reviewed the data and wrote the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5494288	28717360	LT	PLoS52	reviewed the data and wrote the manuscript	reviewed the data and wrote the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5494288	28717360	MM	PLoS52	conducted the experiments	conducted the experiments	Performed the experiments	Investigation	YES
5494288	28717360	MS	PLoS52	designed the study|reviewed the data and wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5494288	28717360	MS	PLoS52	designed the study|reviewed the data and wrote the manuscript	reviewed the data and wrote the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5494288	28717360	MT	PLoS52	conducted the experiments	conducted the experiments	Performed the experiments	Investigation	YES
5494288	28717360	YH	PLoS52	conducted the experiments|reviewed the data and wrote the manuscript	conducted the experiments	Performed the experiments	Investigation	YES
5494288	28717360	YH	PLoS52	conducted the experiments|reviewed the data and wrote the manuscript	reviewed the data and wrote the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5494288	28717360	YS	PLoS52	conducted the experiments	conducted the experiments	Performed the experiments	Investigation	YES
4323759	25685342	Brian O. Kloster	7	Study design, data collection, data analysis, interpretation and writing	Study design, data collection, data analysis, interpretation and writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology	YES
4323759	25685342	Gorm Soendergaard	7	Histological analysis	Histological analysis	Performed the experiments	Investigation	YES
4323759	25685342	Jes S. Lindholt	7	Study design, data analysis, interpretation and writing	Study design, data analysis, interpretation and writing	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology	YES
4323759	25685342	Lars Lund	7	Study design	Study design	Conceived and designed the experiments	Methodology	YES
4016570	24594071	CQ	2	participated in the design of the study	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
4016570	24594071	HJ	2	participated in the manipulation of animal	participated in the manipulation of animal	Performed the experiments	Investigation	YES
4016570	24594071	QW	2	participated in the design of the study	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
4016570	24594071	WW	2	wrote the manuscript, designed the study and analyzed the data	wrote the manuscript, designed the study and analyzed the data	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4016570	24594071	ZC	2	participated in the collection of data of plasma viral load and analyzed the data	participated in the collection of data of plasma viral load and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4403803	25893962	FF	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403803	25893962	FF	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403803	25893962	FF	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403803	25893962	MdD	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4403803	25893962	SJ	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4403803	25893962	SP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403803	25893962	SP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403803	25893962	SP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403803	25893962	SP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403803	25893962	SR	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403803	25893962	SR	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403803	25893962	SR	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403803	25893962	TW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5153868	27964708	CY	2	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5153868	27964708	LL	2	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5153868	27964708	QY	2	contributed equally to this research|conducted the experiments	contributed equally to this research	-	-	NO
5153868	27964708	QY	2	contributed equally to this research|conducted the experiments	conducted the experiments	Performed the experiments	Investigation	YES
5153868	27964708	SZ	2	contributed equally to this research|designed the work and wrote the manuscript	contributed equally to this research	-	-	NO
5153868	27964708	SZ	2	contributed equally to this research|designed the work and wrote the manuscript	designed the work and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
5153868	27964708	WL	2	designed the work and wrote the manuscript	designed the work and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
4323760	25685343	AC	2	contributed in the literature search	contributed in the literature search	-	Formal analysis	YES
4323760	25685343	DN	2	contributed in the public health and epidemiological issues	contributed in the public health and epidemiological issues	-	-	NO
4323760	25685343	EPW	2	substantially contributed to the conception, design and literature search	substantially contributed to the conception, design and literature search	Conceived and designed the experiments	Conceptualization|Formal analysis	YES
4323760	25685343	GE	2	reviewed the pathological aspects of the debate	reviewed the pathological aspects of the debate	Performed the experiments	Investigation	YES
4043700	24894206	All three authors	2	wrote sections of the manuscript	wrote sections of the manuscript	Wrote the paper	Writing - Original Draft	YES
4043700	24894206	VRP	2	was responsible for the integration of the sections	was responsible for the integration of the sections	-	-	NO
5495822	28725230	AK	2	wrote the virology part	wrote the virology part	Wrote the paper	Writing - Original Draft	YES
5495822	28725230	MI	2	wrote the genomic section	wrote the genomic section	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5495822	28725230	MR	2	prepared the outlines and edited extensively primary and subsequent draft of the article	prepared the outlines and edited extensively primary and subsequent draft of the article	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5495822	28725230	YZ	2	conceived the basic idea and gave suggestions to improve the article	conceived the basic idea and gave suggestions to improve the article	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5495822	28725230	ZR	2	wrote the host plant resistance section	wrote the host plant resistance section	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4403804	25894513	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403804	25894513	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4403804	25894513	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403804	25894513	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403804	25894513	LN	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4403804	25894513	MS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403804	25894513	MS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403804	25894513	MS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5878102	29610666	CAS	2	performed experiments and analyzed data	performed experiments and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5878102	29610666	DJS	2	designed the study, performed experiments, analyzed data, and wrote the paper	designed the study, performed experiments, analyzed data, and wrote the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5878102	29610666	FV	2	designed the study, performed experiments, analyzed data, and wrote the paper	designed the study, performed experiments, analyzed data, and wrote the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5878102	29610666	GI	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5878102	29610666	JWD	2	performed experiments and analyzed data	performed experiments and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5878102	29610666	PWB	2	designed the study and wrote the paper	designed the study and wrote the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5878102	29610666	RH	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
4703748	26844285	AM	1	Data analysis and interpretation	Data analysis and interpretation	Analyzed the data	Formal analysis	YES
4703748	26844285	BO	1	Data collection|Data analysis and interpretation	Data collection	Performed the experiments	Investigation	YES
4703748	26844285	BO	1	Data collection|Data analysis and interpretation	Data analysis and interpretation	Analyzed the data	Formal analysis	YES
4703748	26844285	HK	1	Study design|Drafting manuscript	Study design	Conceived and designed the experiments	Methodology	YES
4703748	26844285	HK	1	Study design|Drafting manuscript	Drafting manuscript	Wrote the paper	Writing - Original Draft	YES
4703748	26844285	KM	1	Study design|Data collection|Data analysis and interpretation|Drafting manuscript	Study design	Conceived and designed the experiments	Methodology	YES
4703748	26844285	KM	1	Study design|Data collection|Data analysis and interpretation|Drafting manuscript	Data collection	Performed the experiments	Investigation	YES
4703748	26844285	KM	1	Study design|Data collection|Data analysis and interpretation|Drafting manuscript	Data analysis and interpretation	Analyzed the data	Formal analysis	YES
4703748	26844285	KM	1	Study design|Data collection|Data analysis and interpretation|Drafting manuscript	Drafting manuscript	Wrote the paper	Writing - Original Draft	YES
4703748	26844285	KO	1	Study design|Drafting manuscript	Study design	Conceived and designed the experiments	Methodology	YES
4703748	26844285	KO	1	Study design|Drafting manuscript	Drafting manuscript	Wrote the paper	Writing - Original Draft	YES
4703748	26844285	MI	1	Data analysis and interpretation	Data analysis and interpretation	Analyzed the data	Formal analysis	YES
4703748	26844285	TO	1	Structural modeling	Structural modeling	Performed the experiments	Methodology	YES
4045881	24904682	AAR	1	Conception and design|Acquisition of data	Conception and design	Conceived and designed the experiments	Conceptualization	YES
4045881	24904682	AAR	1	Conception and design|Acquisition of data	Acquisition of data	Performed the experiments	Investigation	YES
4045881	24904682	BW	1	Conception and design|Analysis and interpretation of data|Drafting the manuscript or revising it critically for important intellectual content	Conception and design	Conceived and designed the experiments	Conceptualization	YES
4045881	24904682	BW	1	Conception and design|Analysis and interpretation of data|Drafting the manuscript or revising it critically for important intellectual content	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
4045881	24904682	BW	1	Conception and design|Analysis and interpretation of data|Drafting the manuscript or revising it critically for important intellectual content	Drafting the manuscript or revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4045881	24904682	HB	1	Conception and design|Analysis and interpretation of data|Drafting the manuscript or revising it critically for important intellectual content	Conception and design	Conceived and designed the experiments	Conceptualization	YES
4045881	24904682	HB	1	Conception and design|Analysis and interpretation of data|Drafting the manuscript or revising it critically for important intellectual content	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
4045881	24904682	HB	1	Conception and design|Analysis and interpretation of data|Drafting the manuscript or revising it critically for important intellectual content	Drafting the manuscript or revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4045881	24904682	JB	1	Acquisition of data|Analysis and interpretation of data|Drafting the manuscript or revising it critically for important intellectual content	Acquisition of data	Performed the experiments	Investigation	YES
4045881	24904682	JB	1	Acquisition of data|Analysis and interpretation of data|Drafting the manuscript or revising it critically for important intellectual content	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
4045881	24904682	JB	1	Acquisition of data|Analysis and interpretation of data|Drafting the manuscript or revising it critically for important intellectual content	Drafting the manuscript or revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4045881	24904682	LC	1	Acquisition of data|Drafting the manuscript or revising it critically for important intellectual content	Acquisition of data	Performed the experiments	Investigation	YES
4045881	24904682	LC	1	Acquisition of data|Drafting the manuscript or revising it critically for important intellectual content	Drafting the manuscript or revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4045881	24904682	RBP	1	Conception and design|Drafting the manuscript or revising it critically for important intellectual content	Conception and design	Conceived and designed the experiments	Conceptualization	YES
4045881	24904682	RBP	1	Conception and design|Drafting the manuscript or revising it critically for important intellectual content	Drafting the manuscript or revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4045881	24904682	REB	1	Conception and design|Acquisition of data	Conception and design	Conceived and designed the experiments	Conceptualization	YES
4045881	24904682	REB	1	Conception and design|Acquisition of data	Acquisition of data	Performed the experiments	Investigation	YES
4045881	24904682	RLP	1	Conception and design	Conception and design	Conceived and designed the experiments	Conceptualization	YES
4045881	24904682	RMK	1	Conception and design|Analysis and interpretation of data|Statistical analysis|Drafting the manuscript or revising it critically for important intellectual content	Conception and design	Conceived and designed the experiments	Conceptualization	YES
4045881	24904682	RMK	1	Conception and design|Analysis and interpretation of data|Statistical analysis|Drafting the manuscript or revising it critically for important intellectual content	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
4045881	24904682	RMK	1	Conception and design|Analysis and interpretation of data|Statistical analysis|Drafting the manuscript or revising it critically for important intellectual content	Statistical analysis	Analyzed the data	Formal analysis	YES
4045881	24904682	RMK	1	Conception and design|Analysis and interpretation of data|Statistical analysis|Drafting the manuscript or revising it critically for important intellectual content	Drafting the manuscript or revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4045881	24904682	XDL	1	Conception and design|Acquisition of data|Drafting the manuscript or revising it critically for important intellectual content	Conception and design	Conceived and designed the experiments	Conceptualization	YES
4045881	24904682	XDL	1	Conception and design|Acquisition of data|Drafting the manuscript or revising it critically for important intellectual content	Acquisition of data	Performed the experiments	Investigation	YES
4045881	24904682	XDL	1	Conception and design|Acquisition of data|Drafting the manuscript or revising it critically for important intellectual content	Drafting the manuscript or revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5153897	27955616	AC	2	developed the analysis tools and analyzed the sequence data	developed the analysis tools and analyzed the sequence data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5153897	27955616	GA	2	developed the analysis tools and analyzed the sequence data	developed the analysis tools and analyzed the sequence data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5153897	27955616	GG	2	developed the analysis tools and analyzed the sequence data|edited the manuscript	developed the analysis tools and analyzed the sequence data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5153897	27955616	GG	2	developed the analysis tools and analyzed the sequence data|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5153897	27955616	IP	2	designed the experiments and interpreted the results of all analyses|edited the manuscript	designed the experiments and interpreted the results of all analyses	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5153897	27955616	IP	2	designed the experiments and interpreted the results of all analyses|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5153897	27955616	KK	2	developed the analysis tools and analyzed the sequence data	developed the analysis tools and analyzed the sequence data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5153897	27955616	LA	2	designed the experiments and interpreted the results of all analyses|developed the analysis tools and analyzed the sequence data	designed the experiments and interpreted the results of all analyses	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5153897	27955616	LA	2	designed the experiments and interpreted the results of all analyses|developed the analysis tools and analyzed the sequence data	developed the analysis tools and analyzed the sequence data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5153897	27955616	MP	2	developed the analysis tools and analyzed the sequence data	developed the analysis tools and analyzed the sequence data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5153897	27955616	MR	2	developed the analysis tools and analyzed the sequence data|edited the manuscript	developed the analysis tools and analyzed the sequence data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5153897	27955616	MR	2	developed the analysis tools and analyzed the sequence data|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5153897	27955616	SC	2	designed the experiments and interpreted the results of all analyses	designed the experiments and interpreted the results of all analyses	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5153897	27955616	WW	2	designed the experiments and interpreted the results of all analyses	designed the experiments and interpreted the results of all analyses	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5153897	27955616	YF	2	designed the experiments and interpreted the results of all analyses	designed the experiments and interpreted the results of all analyses	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5495824	28725227	GW	PLoS52	designed the study|wrote the paper|collected the samples	designed the study	Conceived and designed the experiments	Methodology	YES
5495824	28725227	GW	PLoS52	designed the study|wrote the paper|collected the samples	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5495824	28725227	GW	PLoS52	designed the study|wrote the paper|collected the samples	collected the samples	Performed the experiments	Investigation	YES
5495824	28725227	YJ	PLoS52	collected the samples	collected the samples	Performed the experiments	Investigation	YES
5495824	28725227	ZC	PLoS52	wrote the paper|collected the samples|measured the data	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5495824	28725227	ZC	PLoS52	wrote the paper|collected the samples|measured the data	collected the samples	Performed the experiments	Investigation	YES
5495824	28725227	ZC	PLoS52	wrote the paper|collected the samples|measured the data	measured the data	Performed the experiments	Investigation	YES
4403805	25894543	AHL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403805	25894543	AHL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403805	25894543	AHL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403805	25894543	MDG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403805	25894543	MDG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4403805	25894543	MDG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403805	25894543	MDG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403805	25894543	RPC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403805	25894543	RPC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4403805	25894543	RPC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403805	25894543	RPC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403805	25894543	RPC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4566929	25835567	B.S.M.	2	contributed equally	contributed equally	-	-	NO
4566929	25835567	M.H.K.	2	contributed equally	contributed equally	-	-	NO
4061532	24944562	JS	2	collected and verified the data and provided critical revisions to the manuscript	collected and verified the data and provided critical revisions to the manuscript	Performed the experiments|Wrote the paper	Investigation|Validation|Writing - Review & Editing	YES
4061532	24944562	SAA	2	provided critical revisions to the manuscript	provided critical revisions to the manuscript	Wrote the paper	Writing - Review & Editing	YES
4061532	24944562	WHO	2	designed the study, analyzed the data, and prepared the manuscript	designed the study, analyzed the data, and prepared the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5891661	29638269	Sumner Burstein	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5495829	28725233	NK	2	wrote the review article|revised it critically|helped in literature search	wrote the review article	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5495829	28725233	NK	2	wrote the review article|revised it critically|helped in literature search	revised it critically	Wrote the paper	Writing - Review & Editing	YES
5495829	28725233	NK	2	wrote the review article|revised it critically|helped in literature search	helped in literature search	-	Formal analysis	YES
5495829	28725233	NT	2	revised it critically|helped in literature search	revised it critically	Wrote the paper	Writing - Review & Editing	YES
5495829	28725233	NT	2	revised it critically|helped in literature search	helped in literature search	-	Formal analysis	YES
5495829	28725233	PY	2	contributed to the conception of the review article|drafted the work|revised it critically|helped in literature search	contributed to the conception of the review article	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5495829	28725233	PY	2	contributed to the conception of the review article|drafted the work|revised it critically|helped in literature search	drafted the work	Wrote the paper	Writing - Original Draft	YES
5495829	28725233	PY	2	contributed to the conception of the review article|drafted the work|revised it critically|helped in literature search	revised it critically	Wrote the paper	Writing - Review & Editing	YES
5495829	28725233	PY	2	contributed to the conception of the review article|drafted the work|revised it critically|helped in literature search	helped in literature search	-	Formal analysis	YES
5495829	28725233	VY	2	contributed to the conception of the review article|drafted the work|revised it critically	contributed to the conception of the review article	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5495829	28725233	VY	2	contributed to the conception of the review article|drafted the work|revised it critically	drafted the work	Wrote the paper	Writing - Original Draft	YES
5495829	28725233	VY	2	contributed to the conception of the review article|drafted the work|revised it critically	revised it critically	Wrote the paper	Writing - Review & Editing	YES
4086688	25006340	BO	2	performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
4086688	25006340	CB	2	conceived and designed the study|analyzed the data and interpreted the results|wrote the first draft	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4086688	25006340	CB	2	conceived and designed the study|analyzed the data and interpreted the results|wrote the first draft	analyzed the data and interpreted the results	Analyzed the data	Formal analysis	YES
4086688	25006340	CB	2	conceived and designed the study|analyzed the data and interpreted the results|wrote the first draft	wrote the first draft	Wrote the paper	Writing - Original Draft	YES
4086688	25006340	JJ	2	analyzed the data and interpreted the results	analyzed the data and interpreted the results	Analyzed the data	Formal analysis	YES
4086688	25006340	JSzW	2	defined the research theme|conceived and designed the study|analyzed the data and interpreted the results|wrote the first draft	defined the research theme	-	-	NO
4086688	25006340	JSzW	2	defined the research theme|conceived and designed the study|analyzed the data and interpreted the results|wrote the first draft	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4086688	25006340	JSzW	2	defined the research theme|conceived and designed the study|analyzed the data and interpreted the results|wrote the first draft	analyzed the data and interpreted the results	Analyzed the data	Formal analysis	YES
4086688	25006340	JSzW	2	defined the research theme|conceived and designed the study|analyzed the data and interpreted the results|wrote the first draft	wrote the first draft	Wrote the paper	Writing - Original Draft	YES
4086688	25006340	JvL	2	defined the research theme|conceived and designed the study|analyzed the data and interpreted the results|gave important input to the manuscript	defined the research theme	-	-	NO
4086688	25006340	JvL	2	defined the research theme|conceived and designed the study|analyzed the data and interpreted the results|gave important input to the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4086688	25006340	JvL	2	defined the research theme|conceived and designed the study|analyzed the data and interpreted the results|gave important input to the manuscript	analyzed the data and interpreted the results	Analyzed the data	Formal analysis	YES
4086688	25006340	JvL	2	defined the research theme|conceived and designed the study|analyzed the data and interpreted the results|gave important input to the manuscript	gave important input to the manuscript	-	-	NO
4086688	25006340	MH	2	conceived and designed the study|analyzed the data and interpreted the results	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4086688	25006340	MH	2	conceived and designed the study|analyzed the data and interpreted the results	analyzed the data and interpreted the results	Analyzed the data	Formal analysis	YES
4086688	25006340	OD	2	were involved in patient treatment and patient follow-up	were involved in patient treatment and patient follow-up	Performed the experiments	Investigation	YES
4086688	25006340	SH	2	were involved in patient treatment and patient follow-up	were involved in patient treatment and patient follow-up	Performed the experiments	Investigation	YES
4086688	25006340	SL	2	were involved in patient treatment and patient follow-up	were involved in patient treatment and patient follow-up	Performed the experiments	Investigation	YES
4086688	25006340	SS	2	were involved in patient treatment and patient follow-up	were involved in patient treatment and patient follow-up	Performed the experiments	Investigation	YES
4452369	26078971	Saji Uthaman	2	contributed equally	contributed equally	-	-	NO
4452369	26078971	Sang Joon Lee	2	contributed equally	contributed equally	-	-	NO
5154133	27964731	AMT	2	performed the dna extractions	performed the dna extractions	Performed the experiments	Investigation	YES
5154133	27964731	All	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5154133	27964731	All authors	2	contributed to the writing of the manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5154133	27964731	BRJ	2	performed bioinformatics analyses and interpretations	performed bioinformatics analyses and interpretations	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5154133	27964731	KRH	2	conceived the study|performed bioinformatics analyses and interpretations	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5154133	27964731	KRH	2	conceived the study|performed bioinformatics analyses and interpretations	performed bioinformatics analyses and interpretations	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5154133	27964731	MO	2	performed bioinformatics analyses and interpretations	performed bioinformatics analyses and interpretations	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5154133	27964731	MRJC	2	conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4403806	25894078	EIP	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4403806	25894078	EIP	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403806	25894078	KAH	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4403806	25894078	KAH	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403806	25894078	KCC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4403806	25894078	KCC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403806	25894078	LAB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4403806	25894078	LAB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4403806	25894078	LAB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403806	25894078	SEKM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403806	25894078	SEKM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4403806	25894078	SEKM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403806	25894078	SEKM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403806	25894078	SEKM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5495832	28725231	FS	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5495832	28725231	JJPK	PLoS52	performed the experiments|carried out the bioinformatics analyses|analyzed the data|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5495832	28725231	JJPK	PLoS52	performed the experiments|carried out the bioinformatics analyses|analyzed the data|wrote the manuscript	carried out the bioinformatics analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5495832	28725231	JJPK	PLoS52	performed the experiments|carried out the bioinformatics analyses|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5495832	28725231	JJPK	PLoS52	performed the experiments|carried out the bioinformatics analyses|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5495832	28725231	M-RH	PLoS52	designed the experiments|analyzed the data|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5495832	28725231	M-RH	PLoS52	designed the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5495832	28725231	M-RH	PLoS52	designed the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5495832	28725231	MZ	PLoS52	designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5495832	28725231	MZ	PLoS52	designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5495832	28725231	MZ	PLoS52	designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5495832	28725231	MZ	PLoS52	designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5495832	28725231	NC	PLoS52	designed the experiments|analyzed the data|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5495832	28725231	NC	PLoS52	designed the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5495832	28725231	NC	PLoS52	designed the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5495832	28725231	SH	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5495832	28725231	SS	PLoS52	performed the experiments|analyzed the data|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5495832	28725231	SS	PLoS52	performed the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5495832	28725231	SS	PLoS52	performed the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5495832	28725231	US	PLoS52	designed the experiments|analyzed the data|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5495832	28725231	US	PLoS52	designed the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5495832	28725231	US	PLoS52	designed the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4091651	25013451	CS	2	conceived of the study and helped to draft the manuscript	conceived of the study and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4091651	25013451	EK	2	participated in the studys design and helped to draft the manuscript	participated in the studys design and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4091651	25013451	JP	2	conducted the study, performed the statistical analysis and is the main author of the manuscript	conducted the study, performed the statistical analysis and is the main author of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5542917	28824342	HOM	2	was the key individual that designed the study, collected maca from their origin, coordinated the conduct of the study, managed the literature searches and was the lead author of the manuscript	was the key individual that designed the study, collected maca from their origin, coordinated the conduct of the study, managed the literature searches and was the lead author of the manuscript	Conceived and designed the experiments|Performed the experiments	Formal analysis|Investigation|Methodology|Project administration	YES
5542917	28824342	MB	2	was the key individual that conducted laboratory work and managed statistical analyses	was the key individual that conducted laboratory work and managed statistical analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5542917	28824342	PM	2	contributed to genetic profiling work reported in the study	contributed to genetic profiling work reported in the study	Performed the experiments	Investigation	YES
5542917	28824342	PP	2	contributed to design and laboratory work	contributed to design and laboratory work	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5542917	28824342	TB-K	2	contributed to dna study conception and laboratory work	contributed to dna study conception and laboratory work	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
4326117	25973187	EE	7	Drafting and critical revision	Drafting and critical revision	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4326117	25973187	SGO	7	Drafting and critical revision	Drafting and critical revision	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4403807	25894397	AMY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403807	25894397	AMY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4403807	25894397	AMY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403807	25894397	AMY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403807	25894397	DS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403807	25894397	DS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403807	25894397	DS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403807	25894397	DS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4102034	25035708	LS	2	contributed to concept and study design, data interpretation and also critically reviewed the manuscript	contributed to concept and study design, data interpretation and also critically reviewed the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Methodology|Resources|Writing - Review & Editing	YES
4102034	25035708	MK	2	contributed to data acquisition and edited the manuscript	contributed to data acquisition and edited the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4102034	25035708	ML	2	contributed to data acquisition and edited the manuscript	contributed to data acquisition and edited the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4102034	25035708	NC	2	conducted statistical analysis and prepared the first draft of the manuscript	conducted statistical analysis and prepared the first draft of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4102034	25035708	ND	2	contributed to data acquisition and edited the manuscript	contributed to data acquisition and edited the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4102034	25035708	NR	2	contributed to data acquisition and edited the manuscript	contributed to data acquisition and edited the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4102034	25035708	OC	2	prepared study datasets and contributed to data analysis	prepared study datasets and contributed to data analysis	Analyzed the data	Formal analysis	YES
4102034	25035708	TT	2	contributed to concept and study design, data interpretation and also critically reviewed the manuscript	contributed to concept and study design, data interpretation and also critically reviewed the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Methodology|Resources|Writing - Review & Editing	YES
4326118	25973189	AJF	7	Writing, critical revision, final approval	Writing, critical revision, final approval	Wrote the paper	Writing - Review & Editing	YES
4326118	25973189	RAA	7	Concept, critical revision, final approval	Concept, critical revision, final approval	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5495835	28725237	CZ	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5495835	28725237	JW	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5495835	28725237	LD	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5495835	28725237	LW	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5495835	28725237	MZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5495835	28725237	NL	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
5495835	28725237	NL	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5495835	28725237	PX	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5495835	28725237	PX	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5495835	28725237	QC	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5495835	28725237	SZ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5495835	28725237	SZ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5495835	28725237	TL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5495835	28725237	WL	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5495835	28725237	XC	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5154151	27964718	BLM	PLoS52	conceived and designed the experiments|supervised and complemented the writing	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5154151	27964718	BLM	PLoS52	conceived and designed the experiments|supervised and complemented the writing	supervised and complemented the writing	Wrote the paper	Supervision	YES
5154151	27964718	JH	PLoS52	provided technical assistance to analysis of bioinformatic data	provided technical assistance to analysis of bioinformatic data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5154151	27964718	LJN	PLoS52	performed all experiments, analyzed the majority of the data and wrote the article|conceived and designed the experiments	performed all experiments, analyzed the majority of the data and wrote the article	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5154151	27964718	LJN	PLoS52	performed all experiments, analyzed the majority of the data and wrote the article|conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5154151	27964718	MP	PLoS52	metabolite analysis of dhurrin metabolites	metabolite analysis of dhurrin metabolites	-	-	NO
5154151	27964718	NB	PLoS52	conceived and designed the experiments|supervised and complemented the writing	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5154151	27964718	NB	PLoS52	conceived and designed the experiments|supervised and complemented the writing	supervised and complemented the writing	Wrote the paper	Supervision	YES
5154151	27964718	PS	PLoS52	grew and harvested plants	grew and harvested plants	Performed the experiments	Investigation	YES
5154151	27964718	SR	PLoS52	supervised analysis of bioinformatic data and provided computing facilities	supervised analysis of bioinformatic data and provided computing facilities	Analyzed the data	Formal analysis|Supervision	YES
4403808	25894554	AK	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4403808	25894554	AK	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403808	25894554	AK	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403808	25894554	AK	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403808	25894554	DB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4403808	25894554	DB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403808	25894554	DB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403808	25894554	DB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403808	25894554	RL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403808	25894554	RL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403808	25894554	RL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403808	25894554	RL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4102087	25035709	AL	2	participated in data interpretation and performed the statistical analysis	participated in data interpretation and performed the statistical analysis	Analyzed the data	Formal analysis	YES
4102087	25035709	BS	2	designed and conducted the study and prepared and edited the manuscript	designed and conducted the study and prepared and edited the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
4102087	25035709	JW	2	carried out the molecular genetic studies and drafted the manuscript	carried out the molecular genetic studies and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4102087	25035709	LJ	2	participated in data interpretation and performed the statistical analysis	participated in data interpretation and performed the statistical analysis	Analyzed the data	Formal analysis	YES
4102087	25035709	LM	2	participated in the molecular genetic studies and prepared and drafted the manuscript	participated in the molecular genetic studies and prepared and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4102087	25035709	XC	2	participated in data interpretation and performed the statistical analysis	participated in data interpretation and performed the statistical analysis	Analyzed the data	Formal analysis	YES
4102087	25035709	YQ	2	participated in the molecular genetic studies and prepared and drafted the manuscript	participated in the molecular genetic studies and prepared and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4102087	25035709	YS	2	designed and conducted the study and prepared and edited the manuscript	designed and conducted the study and prepared and edited the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
3444837	22997494	A. Amorim	2	conceived the study, and participated in its design and coordination and wrote the paper	conceived the study, and participated in its design and coordination and wrote the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
3444837	22997494	A. Goios	2	participated in the design of the study and wrote the paper	participated in the design of the study and wrote the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3444837	22997494	I. Soares	2	developed the algorithm, performed the tests, and wrote the paper	developed the algorithm, performed the tests, and wrote the paper	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Software|Writing - Original Draft	YES
4740301	26870787	AVSH	2	designed the study|supervised the analysis and conduct of this study	designed the study	Conceived and designed the experiments	Methodology	YES
4740301	26870787	AVSH	2	designed the study|supervised the analysis and conduct of this study	supervised the analysis and conduct of this study	Performed the experiments	Investigation|Supervision	YES
4740301	26870787	All the authors	2	had access to the data and the final decision to submit was made collectively by the authors	had access to the data and the final decision to submit was made collectively by the authors	Performed the experiments	Investigation	YES
4740301	26870787	BPF	2	designed the study|performed wet lab experiments for this study and/or provided expertise and reagents|supervised the analysis and conduct of this study	designed the study	Conceived and designed the experiments	Methodology	YES
4740301	26870787	BPF	2	designed the study|performed wet lab experiments for this study and/or provided expertise and reagents|supervised the analysis and conduct of this study	performed wet lab experiments for this study and/or provided expertise and reagents	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4740301	26870787	BPF	2	designed the study|performed wet lab experiments for this study and/or provided expertise and reagents|supervised the analysis and conduct of this study	supervised the analysis and conduct of this study	Performed the experiments	Investigation|Supervision	YES
4740301	26870787	HAF	2	performed wet lab experiments for this study and/or provided expertise and reagents	performed wet lab experiments for this study and/or provided expertise and reagents	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4740301	26870787	HMS	2	supervised the analysis and conduct of this study	supervised the analysis and conduct of this study	Performed the experiments	Investigation|Supervision	YES
4740301	26870787	JCK	2	designed the study|supervised the analysis and conduct of this study	designed the study	Conceived and designed the experiments	Methodology	YES
4740301	26870787	JCK	2	designed the study|supervised the analysis and conduct of this study	supervised the analysis and conduct of this study	Performed the experiments	Investigation|Supervision	YES
4740301	26870787	MOS	2	performed wet lab experiments for this study and/or provided expertise and reagents	performed wet lab experiments for this study and/or provided expertise and reagents	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4740301	26870787	RT	2	performed wet lab experiments for this study and/or provided expertise and reagents	performed wet lab experiments for this study and/or provided expertise and reagents	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4740301	26870787	VN	2	designed the study|conceived the idea for this study, conducted the analysis and wrote the first draft of the manuscript|performed wet lab experiments for this study and/or provided expertise and reagents	designed the study	Conceived and designed the experiments	Methodology	YES
4740301	26870787	VN	2	designed the study|conceived the idea for this study, conducted the analysis and wrote the first draft of the manuscript|performed wet lab experiments for this study and/or provided expertise and reagents	conceived the idea for this study, conducted the analysis and wrote the first draft of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
4740301	26870787	VN	2	designed the study|conceived the idea for this study, conducted the analysis and wrote the first draft of the manuscript|performed wet lab experiments for this study and/or provided expertise and reagents	performed wet lab experiments for this study and/or provided expertise and reagents	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5159964	27978816	All authors	2	reviewed and approved the manuscript	reviewed and approved the manuscript	Wrote the paper	Writing - Review & Editing	YES
5159964	27978816	EE	2	conceived the study|performed disease screening|performed qtl analysis|constructed linkage map and drafted the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5159964	27978816	EE	2	conceived the study|performed disease screening|performed qtl analysis|constructed linkage map and drafted the manuscript	performed disease screening	Performed the experiments	Investigation	YES
5159964	27978816	EE	2	conceived the study|performed disease screening|performed qtl analysis|constructed linkage map and drafted the manuscript	performed qtl analysis	Performed the experiments	Investigation	YES
5159964	27978816	EE	2	conceived the study|performed disease screening|performed qtl analysis|constructed linkage map and drafted the manuscript	constructed linkage map and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5159964	27978816	JP	2	prepared gbs library	prepared gbs library	-	-	NO
5159964	27978816	MR	2	conceived the study|performed disease screening|performed qtl analysis	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5159964	27978816	MR	2	conceived the study|performed disease screening|performed qtl analysis	performed disease screening	Performed the experiments	Investigation	YES
5159964	27978816	MR	2	conceived the study|performed disease screening|performed qtl analysis	performed qtl analysis	Performed the experiments	Investigation	YES
5159964	27978816	PO	2	conceived the study|developed the segregation population|performed disease screening	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5159964	27978816	PO	2	conceived the study|developed the segregation population|performed disease screening	developed the segregation population	-	-	NO
5159964	27978816	PO	2	conceived the study|developed the segregation population|performed disease screening	performed disease screening	Performed the experiments	Investigation	YES
5159964	27978816	YJ	2	conceived the study|developed the segregation population	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5159964	27978816	YJ	2	conceived the study|developed the segregation population	developed the segregation population	-	-	NO
5495837	28725238	AG	2	performed the gc-ms-based metabolomics approach	performed the gc-ms-based metabolomics approach	Performed the experiments	Investigation	YES
5495837	28725238	IR	2	prepared the figures|interpreted the results	prepared the figures	-	Visualization	YES
5495837	28725238	IR	2	prepared the figures|interpreted the results	interpreted the results	Analyzed the data	Formal analysis	YES
5495837	28725238	JLR	2	performed the gc-ms-based metabolomics approach	performed the gc-ms-based metabolomics approach	Performed the experiments	Investigation	YES
5495837	28725238	JMB	2	conceived and designed the study|interpreted the results|handled the literature	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5495837	28725238	JMB	2	conceived and designed the study|interpreted the results|handled the literature	interpreted the results	Analyzed the data	Formal analysis	YES
5495837	28725238	JMB	2	conceived and designed the study|interpreted the results|handled the literature	handled the literature	-	-	NO
5495837	28725238	LC	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5495837	28725238	MPL-G	2	conceived and designed the study|carried out the experiments|performed the gc-ms-based metabolomics approach|did the data processing and statistical analysis|interpreted the results|wrote the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5495837	28725238	MPL-G	2	conceived and designed the study|carried out the experiments|performed the gc-ms-based metabolomics approach|did the data processing and statistical analysis|interpreted the results|wrote the manuscript	carried out the experiments	Performed the experiments	Investigation	YES
5495837	28725238	MPL-G	2	conceived and designed the study|carried out the experiments|performed the gc-ms-based metabolomics approach|did the data processing and statistical analysis|interpreted the results|wrote the manuscript	performed the gc-ms-based metabolomics approach	Performed the experiments	Investigation	YES
5495837	28725238	MPL-G	2	conceived and designed the study|carried out the experiments|performed the gc-ms-based metabolomics approach|did the data processing and statistical analysis|interpreted the results|wrote the manuscript	did the data processing and statistical analysis	Analyzed the data	Data curation|Formal analysis	YES
5495837	28725238	MPL-G	2	conceived and designed the study|carried out the experiments|performed the gc-ms-based metabolomics approach|did the data processing and statistical analysis|interpreted the results|wrote the manuscript	interpreted the results	Analyzed the data	Formal analysis	YES
5495837	28725238	MPL-G	2	conceived and designed the study|carried out the experiments|performed the gc-ms-based metabolomics approach|did the data processing and statistical analysis|interpreted the results|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5495837	28725238	PL	2	carried out the experiments|did the data processing and statistical analysis|interpreted the results|wrote the manuscript	carried out the experiments	Performed the experiments	Investigation	YES
5495837	28725238	PL	2	carried out the experiments|did the data processing and statistical analysis|interpreted the results|wrote the manuscript	did the data processing and statistical analysis	Analyzed the data	Data curation|Formal analysis	YES
5495837	28725238	PL	2	carried out the experiments|did the data processing and statistical analysis|interpreted the results|wrote the manuscript	interpreted the results	Analyzed the data	Formal analysis	YES
5495837	28725238	PL	2	carried out the experiments|did the data processing and statistical analysis|interpreted the results|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5495837	28725238	VC	2	interpreted the results	interpreted the results	Analyzed the data	Formal analysis	YES
5927802	29736243	AP	2	participated in the design and execution of the trial	participated in the design and execution of the trial	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5927802	29736243	All authors	2	participated in the interpretation, critical review, and revision of the final manuscript	participated in the interpretation, critical review, and revision of the final manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5927802	29736243	CD	2	participated in the design and interpretation of the trial	participated in the design and interpretation of the trial	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5927802	29736243	CW	2	participated in the execution, oversight, and analysis of the trial and its data	participated in the execution, oversight, and analysis of the trial and its data	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Supervision	YES
5927802	29736243	DA	2	participated in the design and interpretation of the trial	participated in the design and interpretation of the trial	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5927802	29736243	DBS	2	participated in the design and interpretation of the trial	participated in the design and interpretation of the trial	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5927802	29736243	GP	2	participated in the design and interpretation of the trial	participated in the design and interpretation of the trial	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5927802	29736243	JF	2	participated in the design and execution of the trial	participated in the design and execution of the trial	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5927802	29736243	JH	2	participated in the design and interpretation of the trial	participated in the design and interpretation of the trial	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5927802	29736243	JV	2	participated in the design and execution of the trial	participated in the design and execution of the trial	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5927802	29736243	LV	2	participated in the design and interpretation of the trial	participated in the design and interpretation of the trial	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5927802	29736243	M-CH	2	participated in the design and execution of the trial	participated in the design and execution of the trial	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5927802	29736243	MWM	2	participated in the design and execution of the trial	participated in the design and execution of the trial	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5927802	29736243	QZ	2	oversaw the bioanalysis of the plasma samples from this study and reviewed the bioanalytical and pharmacokinetic data generated	oversaw the bioanalysis of the plasma samples from this study and reviewed the bioanalytical and pharmacokinetic data generated	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Supervision	YES
5927802	29736243	SMC	2	participated in the design and interpretation of the trial	participated in the design and interpretation of the trial	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5927802	29736243	TNK	2	participated in the design and execution of the trial	participated in the design and execution of the trial	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4107492	25057277	CB	2	contributed to neuroradiologic examinations, provided mri images and interpretation and revised the manuscript for publication	contributed to neuroradiologic examinations, provided mri images and interpretation and revised the manuscript for publication	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Visualization|Writing - Review & Editing	YES
4107492	25057277	ET	2	was responsible for the primary care of the patient, revised the draft, prepared the figure for publication and was responsible for the final manuscript	was responsible for the primary care of the patient, revised the draft, prepared the figure for publication and was responsible for the final manuscript	Performed the experiments|Wrote the paper	Investigation|Visualization|Writing - Original Draft|Writing - Review & Editing	YES
4107492	25057277	L-GL	2	contributed to the care of the patient and revised all versions of the manuscript	contributed to the care of the patient and revised all versions of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4107492	25057277	MA	2	drafted the manuscript and revised all versions	drafted the manuscript and revised all versions	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4107492	25057277	YR	2	performed the neuropathological examination, documented the cerebral microsporidiosis, provided the brain section images and interpretation, and revised the manuscript	performed the neuropathological examination, documented the cerebral microsporidiosis, provided the brain section images and interpretation, and revised the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Visualization|Writing - Review & Editing	YES
4403809	25894582	AATN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403809	25894582	AATN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4403809	25894582	AATN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403809	25894582	AATN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403809	25894582	AATN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403809	25894582	FA	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403809	25894582	FA	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403809	25894582	MIH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to workstation management	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403809	25894582	MIH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to workstation management	Performed the experiments	Performed the experiments	Investigation	YES
4403809	25894582	MIH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to workstation management	Analyzed the data	Analyzed the data	Formal analysis	YES
4403809	25894582	MIH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to workstation management	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403809	25894582	MIH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to workstation management	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403809	25894582	MIH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to workstation management	Contributed to workstation management	Analyzed the data	Formal analysis	YES
4403809	25894582	MS	PLoS5	Performed the experiments|Analyzed the data|Contributed to workstation management	Performed the experiments	Performed the experiments	Investigation	YES
4403809	25894582	MS	PLoS5	Performed the experiments|Analyzed the data|Contributed to workstation management	Analyzed the data	Analyzed the data	Formal analysis	YES
4403809	25894582	MS	PLoS5	Performed the experiments|Analyzed the data|Contributed to workstation management	Contributed to workstation management	Analyzed the data	Formal analysis	YES
4740302	26870799	JL	PLoS52	planned overall concepts|designed experiments|interpreted data	planned overall concepts	Conceived and designed the experiments	Conceptualization	YES
4740302	26870799	JL	PLoS52	planned overall concepts|designed experiments|interpreted data	designed experiments	Conceived and designed the experiments	Methodology	YES
4740302	26870799	JL	PLoS52	planned overall concepts|designed experiments|interpreted data	interpreted data	Analyzed the data	Formal analysis	YES
4740302	26870799	ML	PLoS52	planned overall concepts|designed experiments|interpreted data|wrote the paper	planned overall concepts	Conceived and designed the experiments	Conceptualization	YES
4740302	26870799	ML	PLoS52	planned overall concepts|designed experiments|interpreted data|wrote the paper	designed experiments	Conceived and designed the experiments	Methodology	YES
4740302	26870799	ML	PLoS52	planned overall concepts|designed experiments|interpreted data|wrote the paper	interpreted data	Analyzed the data	Formal analysis	YES
4740302	26870799	ML	PLoS52	planned overall concepts|designed experiments|interpreted data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4740302	26870799	MN	PLoS52	planned overall concepts|wrote the paper	planned overall concepts	Conceived and designed the experiments	Conceptualization	YES
4740302	26870799	MN	PLoS52	planned overall concepts|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403810	25894842	CC	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4403810	25894842	CW	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403810	25894842	LL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403810	25894842	SCL	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403810	25894842	TY	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403810	25894842	XY	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Designed the software used in analysis	Performed the experiments	Performed the experiments	Investigation	YES
4403810	25894842	XY	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Designed the software used in analysis	Analyzed the data	Analyzed the data	Formal analysis	YES
4403810	25894842	XY	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Designed the software used in analysis	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403810	25894842	XY	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Designed the software used in analysis	Designed the software used in analysis	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
4403810	25894842	YY	PLoS5	Performed the experiments|Designed the software used in analysis	Performed the experiments	Performed the experiments	Investigation	YES
4403810	25894842	YY	PLoS5	Performed the experiments|Designed the software used in analysis	Designed the software used in analysis	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
4403810	25894842	ZLL	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5542920	28824345	Hiroshi Shimoda	PLoS5	Analyzed and interpreted the data	Analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5542920	28824345	Kazuya Toda	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed and interpreted the data|Contributed reagents, materials, analysis tools, or data|Wrote the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5542920	28824345	Kazuya Toda	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed and interpreted the data|Contributed reagents, materials, analysis tools, or data|Wrote the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
5542920	28824345	Kazuya Toda	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed and interpreted the data|Contributed reagents, materials, analysis tools, or data|Wrote the manuscript	Analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5542920	28824345	Kazuya Toda	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed and interpreted the data|Contributed reagents, materials, analysis tools, or data|Wrote the manuscript	Contributed reagents, materials, analysis tools, or data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5542920	28824345	Kazuya Toda	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed and interpreted the data|Contributed reagents, materials, analysis tools, or data|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5542920	28824345	Norihito Shimizu	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5542920	28824345	Shogo Takeda	PLoS5	Performed the experiments|Analyzed and interpreted the data	Performed the experiments	Performed the experiments	Investigation	YES
5542920	28824345	Shogo Takeda	PLoS5	Performed the experiments|Analyzed and interpreted the data	Analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5542920	28824345	Shoketsu Hitoe	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5159998	27978833	JAP	2	performed the bioinformatics analyses	performed the bioinformatics analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5159998	27978833	JDW	2	prepared the dna and helped analyze the data and prepare the manuscript	prepared the dna and helped analyze the data and prepare the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5159998	27978833	KLC	2	performed the bioinformatics analyses	performed the bioinformatics analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5495857	28725236	XQH	2	did another part of the experiment	did another part of the experiment	Performed the experiments	Investigation	YES
5495857	28725236	XWH	2	made some comments in writing paper	made some comments in writing paper	Wrote the paper	Writing - Original Draft	YES
5495857	28725236	YL	2	did part of the experiment and write the paper	did part of the experiment and write the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5495857	28725236	YW	2	provided the guidelines and reversed the manuscript several times and provided the funding	provided the guidelines and reversed the manuscript several times and provided the funding	-	Funding acquisition	YES
4124773	25104967	HW	2	conceived the study and participated in the data analysis|supervised and coordinated the study	conceived the study and participated in the data analysis	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
4124773	25104967	HW	2	conceived the study and participated in the data analysis|supervised and coordinated the study	supervised and coordinated the study	-	Project administration|Supervision	YES
4124773	25104967	TZ	2	followed up patients and collected samples	followed up patients and collected samples	Performed the experiments	Investigation	YES
4124773	25104967	WL	2	assisted with flow cytometric analysis and data acquisition	assisted with flow cytometric analysis and data acquisition	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4124773	25104967	XH	2	assisted with manuscript and data anlysis	assisted with manuscript and data anlysis	-	-	NO
4124773	25104967	XS	2	participated in flow cytometric analysis|assisted with manuscript and data anlysis	participated in flow cytometric analysis	Performed the experiments	Investigation	YES
4124773	25104967	XS	2	participated in flow cytometric analysis|assisted with manuscript and data anlysis	assisted with manuscript and data anlysis	-	-	NO
4124773	25104967	YJ	2	drafted the manuscript and statistical analyses|assisted with flow cytometric analysis and data acquisition	drafted the manuscript and statistical analyses	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4124773	25104967	YJ	2	drafted the manuscript and statistical analyses|assisted with flow cytometric analysis and data acquisition	assisted with flow cytometric analysis and data acquisition	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5943670	29760929	FWD	2	designed the study|reviewed the paper and all authors approved the final version of the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5943670	29760929	FWD	2	designed the study|reviewed the paper and all authors approved the final version of the manuscript	reviewed the paper and all authors approved the final version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5943670	29760929	IS	2	designed the study|prepared the draft of the manuscript|had full access to all the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis	designed the study	Conceived and designed the experiments	Methodology	YES
5943670	29760929	IS	2	designed the study|prepared the draft of the manuscript|had full access to all the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis	prepared the draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
5943670	29760929	IS	2	designed the study|prepared the draft of the manuscript|had full access to all the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis	had full access to all the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis	Analyzed the data	Data curation|Formal analysis	YES
5943670	29760929	PI	2	designed the study|managed and analyzed the data|prepared the draft of the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5943670	29760929	PI	2	designed the study|managed and analyzed the data|prepared the draft of the manuscript	managed and analyzed the data	Analyzed the data	Data curation|Formal analysis	YES
5943670	29760929	PI	2	designed the study|managed and analyzed the data|prepared the draft of the manuscript	prepared the draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
4403811	25894337	AI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403811	25894337	AI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4403811	25894337	AI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403811	25894337	AI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403811	25894337	AKT	PLoS5	Contributed reagents/materials/analysis tools|Peptide preparation and coupling reactions|Revised the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403811	25894337	AKT	PLoS5	Contributed reagents/materials/analysis tools|Peptide preparation and coupling reactions|Revised the paper	Peptide preparation and coupling reactions	Performed the experiments	Investigation	YES
4403811	25894337	AKT	PLoS5	Contributed reagents/materials/analysis tools|Peptide preparation and coupling reactions|Revised the paper	Revised the paper	Wrote the paper	Writing - Review & Editing	YES
4403811	25894337	CK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Revised the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403811	25894337	CK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Revised the paper	Performed the experiments	Performed the experiments	Investigation	YES
4403811	25894337	CK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Revised the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403811	25894337	CK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Revised the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403811	25894337	CK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Revised the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403811	25894337	CK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Revised the paper	Revised the paper	Wrote the paper	Writing - Review & Editing	YES
4403811	25894337	MB	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403811	25894337	YZ	PLoS5	Peptide preparation and coupling reactions|Revised the paper	Peptide preparation and coupling reactions	Performed the experiments	Investigation	YES
4403811	25894337	YZ	PLoS5	Peptide preparation and coupling reactions|Revised the paper	Revised the paper	Wrote the paper	Writing - Review & Editing	YES
4124775	25104966	AS	2	managed the patients and helped to interpret the findings	managed the patients and helped to interpret the findings	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4124775	25104966	CM	2	interpreted the data and performed the statistical analysis	interpreted the data and performed the statistical analysis	Analyzed the data	Formal analysis	YES
4124775	25104966	GP	2	helped to design the study and write the paper	helped to design the study and write the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4124775	25104966	MB	2	collected the data, interpreted the findings, and wrote the paper	collected the data, interpreted the findings, and wrote the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4124775	25104966	MC	2	helped to interpret the findings and wrote the paper	helped to interpret the findings and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4124775	25104966	MF	2	managed the patients and interpret the findings|helped to interpret the findings and write the paper	managed the patients and interpret the findings	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4124775	25104966	MF	2	managed the patients and interpret the findings|helped to interpret the findings and write the paper	helped to interpret the findings and write the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4124775	25104966	RS	2	managed the patients and wrote the paper	managed the patients and wrote the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4124775	25104966	SGP	2	designed and coordinated the study, interpreted the findings, and wrote the paper	designed and coordinated the study, interpreted the findings, and wrote the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Project administration|Writing - Original Draft	YES
5495867	28725228	All authors	2	contributed to the final version of the manuscript	contributed to the final version of the manuscript	-	-	NO
5495867	28725228	FM	2	participated in samplings, as well as in the design of the photoinhibition experiment in growth chambers|determined pigment content, analyzed all the results and wrote the first draft of the manuscript	participated in samplings, as well as in the design of the photoinhibition experiment in growth chambers	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5495867	28725228	FM	2	participated in samplings, as well as in the design of the photoinhibition experiment in growth chambers|determined pigment content, analyzed all the results and wrote the first draft of the manuscript	determined pigment content, analyzed all the results and wrote the first draft of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5495867	28725228	JG	2	participated in the interpretation of the results, as well as in the preparation and editing of the manuscript	participated in the interpretation of the results, as well as in the preparation and editing of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5495867	28725228	LG	2	participated in samplings, as well as in the design of the photoinhibition experiment in growth chambers|determined sugar contents	participated in samplings, as well as in the design of the photoinhibition experiment in growth chambers	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5495867	28725228	LG	2	participated in samplings, as well as in the design of the photoinhibition experiment in growth chambers|determined sugar contents	determined sugar contents	-	-	NO
5495867	28725228	UK	2	participated in the interpretation of the results, as well as in the preparation and editing of the manuscript	participated in the interpretation of the results, as well as in the preparation and editing of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5495867	28725228	US	2	designed and participated in field expedition, determining sampling sites and collecting, identifying and maintaining the lichen species	designed and participated in field expedition, determining sampling sites and collecting, identifying and maintaining the lichen species	Conceived and designed the experiments|Performed the experiments	Investigation	YES
516027	15310404	DN	2	participated in the preparation and utilization of array experiments used for the identification of stably expressed genes	participated in the preparation and utilization of array experiments used for the identification of stably expressed genes	Performed the experiments	Investigation	YES
516027	15310404	EW	2	provided leadership for the development of cdna arrays, transcriptome array and for the overall conduct of the experiments	provided leadership for the development of cdna arrays, transcriptome array and for the overall conduct of the experiments	Performed the experiments	Investigation|Supervision	YES
516027	15310404	FMM	2	supervise the project as principal investigator	supervise the project as principal investigator	Conceived and designed the experiments	Conceptualization|Funding acquisition|Supervision	YES
516027	15310404	HS	2	provided a large library of samples necessary for the development of the transcriptome array	provided a large library of samples necessary for the development of the transcriptome array	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
516027	15310404	KS	2	participated in the preparation and utilization of array experiments used for the identification of stably expressed genes	participated in the preparation and utilization of array experiments used for the identification of stably expressed genes	Performed the experiments	Investigation	YES
516027	15310404	MCP	2	participated in the preparation and utilization of array experiments used for the identification of stably expressed genes	participated in the preparation and utilization of array experiments used for the identification of stably expressed genes	Performed the experiments	Investigation	YES
516027	15310404	NH	2	provided a large library of samples necessary for the development of the transcriptome array	provided a large library of samples necessary for the development of the transcriptome array	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
516027	15310404	PJ	2	validated the system combining high-throughput data with gene-directed analysis by quantitative real time pcr	validated the system combining high-throughput data with gene-directed analysis by quantitative real time pcr	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Supervision|Validation	YES
516027	15310404	PRT	2	provided a large library of samples necessary for the development of the transcriptome array	provided a large library of samples necessary for the development of the transcriptome array	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
516027	15310404	VM	2	participated in the preparation and utilization of array experiments used for the identification of stably expressed genes	participated in the preparation and utilization of array experiments used for the identification of stably expressed genes	Performed the experiments	Investigation	YES
516027	15310404	YN	2	participated in the preparation and utilization of array experiments used for the identification of stably expressed genes	participated in the preparation and utilization of array experiments used for the identification of stably expressed genes	Performed the experiments	Investigation	YES
516027	15310404	YZ	2	performed statistical analysis	performed statistical analysis	Analyzed the data	Formal analysis	YES
4740305	26870793	AH	PLoS52	collected samples and carried out experimental work|analysed the data|prepared the manuscript	collected samples and carried out experimental work	Performed the experiments	Investigation	YES
4740305	26870793	AH	PLoS52	collected samples and carried out experimental work|analysed the data|prepared the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
4740305	26870793	AH	PLoS52	collected samples and carried out experimental work|analysed the data|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
4740305	26870793	DCR	PLoS52	designed the study|prepared the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
4740305	26870793	DCR	PLoS52	designed the study|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
4740305	26870793	JSG	PLoS52	designed the study|prepared the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
4740305	26870793	JSG	PLoS52	designed the study|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
4740305	26870793	ST	PLoS52	collected samples and carried out experimental work	collected samples and carried out experimental work	Performed the experiments	Investigation	YES
4326125	25973186	CFC	7	Concept, Critical Revision, Final Approval	Concept, Critical Revision, Final Approval	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
4326125	25973186	PJT	7	Writing, Critical Revision, Final Approval	Writing, Critical Revision, Final Approval	Wrote the paper	Writing - Review & Editing	YES
4130425	25120580	AC	2	managed the case, and were involved in the interpretation of the data|helped in drafting the manuscript	managed the case, and were involved in the interpretation of the data	Analyzed the data	Data curation|Formal analysis	YES
4130425	25120580	AC	2	managed the case, and were involved in the interpretation of the data|helped in drafting the manuscript	helped in drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
4130425	25120580	All authors	2	were involved in critically revising the manuscript|all read and approved the final manuscript	were involved in critically revising the manuscript	Wrote the paper	Writing - Review & Editing	YES
4130425	25120580	All authors	2	were involved in critically revising the manuscript|all read and approved the final manuscript	all read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4130425	25120580	CS	2	managed the case, and were involved in the interpretation of the data|helped in drafting the manuscript	managed the case, and were involved in the interpretation of the data	Analyzed the data	Data curation|Formal analysis	YES
4130425	25120580	CS	2	managed the case, and were involved in the interpretation of the data|helped in drafting the manuscript	helped in drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
4130425	25120580	JD	2	managed the case, and were involved in the interpretation of the data	managed the case, and were involved in the interpretation of the data	Analyzed the data	Data curation|Formal analysis	YES
4130425	25120580	KIL	2	helped in drafting the manuscript	helped in drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
4130425	25120580	ME	2	managed the case, and were involved in the interpretation of the data|helped in drafting the manuscript	managed the case, and were involved in the interpretation of the data	Analyzed the data	Data curation|Formal analysis	YES
4130425	25120580	ME	2	managed the case, and were involved in the interpretation of the data|helped in drafting the manuscript	helped in drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
4130425	25120580	Marc Fathi	2	did the therapeutic drug monitoring	did the therapeutic drug monitoring	-	Supervision	YES
4130425	25120580	Michela Rebsamen	2	performed and interpreted cyp2c19 genotyping	performed and interpreted cyp2c19 genotyping	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4130425	25120580	SD	2	managed the case, and were involved in the interpretation of the data	managed the case, and were involved in the interpretation of the data	Analyzed the data	Data curation|Formal analysis	YES
4130425	25120580	YB	2	managed the case, and were involved in the interpretation of the data|drafted the manuscript	managed the case, and were involved in the interpretation of the data	Analyzed the data	Data curation|Formal analysis	YES
4130425	25120580	YB	2	managed the case, and were involved in the interpretation of the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4130425	25120580	YD	2	performed and interpreted the phenotype measurement for cyp2c19	performed and interpreted the phenotype measurement for cyp2c19	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4403819	25893523	AR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403819	25893523	AR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4403819	25893523	AR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403819	25893523	AR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403819	25893523	JT	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4403819	25893523	KB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403819	25893523	KB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4403819	25893523	KB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403819	25893523	MN	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4403819	25893523	OL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
516028	15318950	All the authors	2	reviewed and accepted the final version of the paper	reviewed and accepted the final version of the paper	Wrote the paper	Writing - Review & Editing	YES
516028	15318950	B.M.	2	reviewed and accepted the final version of the paper	reviewed and accepted the final version of the paper	Wrote the paper	Writing - Review & Editing	YES
516028	15318950	G.Z.	2	were actively involved in the programming, database construction, and testing of the software	were actively involved in the programming, database construction, and testing of the software	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
516028	15318950	H.L.	2	were actively involved in the programming, database construction, and testing of the software	were actively involved in the programming, database construction, and testing of the software	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
516028	15318950	M.P.	2	were actively involved in the programming, database construction, and testing of the software	were actively involved in the programming, database construction, and testing of the software	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
516028	15318950	M.S.	2	were actively involved in the programming, database construction, and testing of the software	were actively involved in the programming, database construction, and testing of the software	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
516028	15318950	M.W.D.	2	reviewed and accepted the final version of the paper	reviewed and accepted the final version of the paper	Wrote the paper	Writing - Review & Editing	YES
516028	15318950	P.J.T.	2	were actively involved in the programming, database construction, and testing of the software	were actively involved in the programming, database construction, and testing of the software	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
516028	15318950	R.D.	2	reviewed and accepted the final version of the paper	reviewed and accepted the final version of the paper	Wrote the paper	Writing - Review & Editing	YES
516028	15318950	T.B.	2	reviewed and accepted the final version of the paper	reviewed and accepted the final version of the paper	Wrote the paper	Writing - Review & Editing	YES
516028	15318950	X.W.	2	were actively involved in the programming, database construction, and testing of the software	were actively involved in the programming, database construction, and testing of the software	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
3444857	22997496	A. K. De	PLoS52	participated in the acquisition, analysis, and interpretation of the data|wrote the paper	participated in the acquisition, analysis, and interpretation of the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3444857	22997496	A. K. De	PLoS52	participated in the acquisition, analysis, and interpretation of the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3444857	22997496	All the authors	PLoS52	participated in the design of the experiment	participated in the design of the experiment	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3444857	22997496	C. Boulocher	PLoS52	participated in the acquisition, analysis, and interpretation of the data|wrote the paper	participated in the acquisition, analysis, and interpretation of the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3444857	22997496	C. Boulocher	PLoS52	participated in the acquisition, analysis, and interpretation of the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3444857	22997496	S. Sawaya	PLoS52	participated in the acquisition, analysis, and interpretation of the data	participated in the acquisition, analysis, and interpretation of the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5496946	28725234	AB	2	wrote the manuscript and contributed to the interpretation of the results	wrote the manuscript and contributed to the interpretation of the results	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5496946	28725234	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5496946	28725234	BM	2	performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
5496946	28725234	CL	2	wrote the manuscript and contributed to the interpretation of the results|designed the experiments|coordinated the project	wrote the manuscript and contributed to the interpretation of the results	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5496946	28725234	CL	2	wrote the manuscript and contributed to the interpretation of the results|designed the experiments|coordinated the project	designed the experiments	Conceived and designed the experiments	Methodology	YES
5496946	28725234	CL	2	wrote the manuscript and contributed to the interpretation of the results|designed the experiments|coordinated the project	coordinated the project	-	Project administration	YES
5496946	28725234	FG	2	performed the cdrgs analysis	performed the cdrgs analysis	Performed the experiments	Investigation	YES
5496946	28725234	JL	2	performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
5496946	28725234	JS	2	carried out the cbb phenotyping and qtl analysis|wrote the manuscript and contributed to the interpretation of the results|designed the experiments	carried out the cbb phenotyping and qtl analysis	Performed the experiments	Investigation	YES
5496946	28725234	JS	2	carried out the cbb phenotyping and qtl analysis|wrote the manuscript and contributed to the interpretation of the results|designed the experiments	wrote the manuscript and contributed to the interpretation of the results	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5496946	28725234	JS	2	carried out the cbb phenotyping and qtl analysis|wrote the manuscript and contributed to the interpretation of the results|designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5496946	28725234	RM	2	conducted part of the cbb phenotyping	conducted part of the cbb phenotyping	Performed the experiments	Investigation	YES
4130435	25120579	JD	2	assisted with study implementation and preparing the manuscript	assisted with study implementation and preparing the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4130435	25120579	JDL	2	assisted with study implementation and preparing the manuscript	assisted with study implementation and preparing the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4130435	25120579	JPC	2	assisted with study design	assisted with study design	Conceived and designed the experiments	Methodology	YES
4130435	25120579	JTC	2	designed and conducted the study, interpreted the data and prepared and edited the manuscript	designed and conducted the study, interpreted the data and prepared and edited the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
4130435	25120579	MC	2	provided statistical expertise, interpreted the data and edited the manuscript	provided statistical expertise, interpreted the data and edited the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
4130435	25120579	RBI	2	designed and conducted the study, interpreted the data and prepared and edited the manuscript	designed and conducted the study, interpreted the data and prepared and edited the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
4130435	25120579	VES	2	provided oversight of study design and manuscript preparation, and edited the manuscript	provided oversight of study design and manuscript preparation, and edited the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
4403820	25893896	QBS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403820	25893896	QBS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403820	25893896	QBS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403820	25893896	QBS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403820	25893896	XYZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403820	25893896	XYZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4403820	25893896	XYZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403820	25893896	XYZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403820	25893896	XYZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5980133	29864242	ERF	1	Wrote or contributed to the writing of the manuscript	Wrote or contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5980133	29864242	GL	1	Modeling and simulation|Wrote or contributed to the writing of the manuscript	Modeling and simulation	Performed the experiments	Formal analysis|Methodology	YES
5980133	29864242	GL	1	Modeling and simulation|Wrote or contributed to the writing of the manuscript	Wrote or contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5980133	29864242	GS	1	Participated in the design of monkey studies|Performed data analysis|Wrote or contributed to the writing of the manuscript	Participated in the design of monkey studies	Conceived and designed the experiments	Methodology	YES
5980133	29864242	GS	1	Participated in the design of monkey studies|Performed data analysis|Wrote or contributed to the writing of the manuscript	Performed data analysis	Analyzed the data	Formal analysis	YES
5980133	29864242	GS	1	Participated in the design of monkey studies|Performed data analysis|Wrote or contributed to the writing of the manuscript	Wrote or contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5980133	29864242	JY	1	Participated in the design of monkey studies|Performed data analysis|Wrote or contributed to the writing of the manuscript	Participated in the design of monkey studies	Conceived and designed the experiments	Methodology	YES
5980133	29864242	JY	1	Participated in the design of monkey studies|Performed data analysis|Wrote or contributed to the writing of the manuscript	Performed data analysis	Analyzed the data	Formal analysis	YES
5980133	29864242	JY	1	Participated in the design of monkey studies|Performed data analysis|Wrote or contributed to the writing of the manuscript	Wrote or contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5980133	29864242	LZ	1	Participated in the design of monkey studies|Performed data analysis|Wrote or contributed to the writing of the manuscript	Participated in the design of monkey studies	Conceived and designed the experiments	Methodology	YES
5980133	29864242	LZ	1	Participated in the design of monkey studies|Performed data analysis|Wrote or contributed to the writing of the manuscript	Performed data analysis	Analyzed the data	Formal analysis	YES
5980133	29864242	LZ	1	Participated in the design of monkey studies|Performed data analysis|Wrote or contributed to the writing of the manuscript	Wrote or contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5980133	29864242	NP	1	Modeling and simulation|Wrote or contributed to the writing of the manuscript	Modeling and simulation	Performed the experiments	Formal analysis|Methodology	YES
5980133	29864242	NP	1	Modeling and simulation|Wrote or contributed to the writing of the manuscript	Wrote or contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5980133	29864242	SR	1	Participated in the design of monkey studies|Modeling and simulation|Performed data analysis|Wrote or contributed to the writing of the manuscript	Participated in the design of monkey studies	Conceived and designed the experiments	Methodology	YES
5980133	29864242	SR	1	Participated in the design of monkey studies|Modeling and simulation|Performed data analysis|Wrote or contributed to the writing of the manuscript	Modeling and simulation	Performed the experiments	Formal analysis|Methodology	YES
5980133	29864242	SR	1	Participated in the design of monkey studies|Modeling and simulation|Performed data analysis|Wrote or contributed to the writing of the manuscript	Performed data analysis	Analyzed the data	Formal analysis	YES
5980133	29864242	SR	1	Participated in the design of monkey studies|Modeling and simulation|Performed data analysis|Wrote or contributed to the writing of the manuscript	Wrote or contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5162099	27986076	DDS	PLoS52	conceived, designed and conducted the experiments|wrote the manuscript	conceived, designed and conducted the experiments	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
5162099	27986076	DDS	PLoS52	conceived, designed and conducted the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5162099	27986076	KSM	PLoS52	covered the cost from their projects and edited the manuscript	covered the cost from their projects and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5162099	27986076	MCS	PLoS52	covered the cost from their projects and edited the manuscript	covered the cost from their projects and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5162099	27986076	NK	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5162099	27986076	SM	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5162099	27986076	SRU	PLoS52	conceived, designed and conducted the experiments	conceived, designed and conducted the experiments	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
5162099	27986076	YT	PLoS52	managed the sequencing	managed the sequencing	Performed the experiments	Investigation	YES
5496956	28725229	CW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5496956	28725229	GG	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5496956	28725229	JH	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5496956	28725229	JX	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5496956	28725229	MS	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5496956	28725229	WH	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
5496956	28725229	WH	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5496956	28725229	YH	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5496956	28725229	YL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5496956	28725229	YaG	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5496956	28725229	YaG	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5496956	28725229	YuG	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5496956	28725229	ZL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5496956	28725229	ZL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
5496956	28725229	ZL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5496956	28725229	ZL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4130436	25120578	JN	2	participated in the study design and drafting the manuscript	participated in the study design and drafting the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4740331	26870808	AH	2	collected, organized and interpreted data and edited the manuscript	collected, organized and interpreted data and edited the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
4740331	26870808	DE	2	interpreted data and edited the manuscript	interpreted data and edited the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4740331	26870808	JY	2	interpreted data and edited the manuscript	interpreted data and edited the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4740331	26870808	LSR	2	collected, organized and interpreted data and wrote the manuscript	collected, organized and interpreted data and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4740331	26870808	MP	2	collected, organized and interpreted data and edited the manuscript	collected, organized and interpreted data and edited the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
4740331	26870808	PR	2	collected data	collected data	Performed the experiments	Investigation	YES
4740331	26870808	SP	2	collected data	collected data	Performed the experiments	Investigation	YES
4740331	26870808	SPM	2	collected, organized and interpreted data and edited the manuscript	collected, organized and interpreted data and edited the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
4740331	26870808	TSR	2	collected, organized and interpreted data and wrote the manuscript	collected, organized and interpreted data and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4740331	26870808	XJX	2	interpreted data and edited the manuscript	interpreted data and edited the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4348450	25750727	Jasmine Ehsanullah	2	made substantial contributions to the study conception and design, data collection, data analysis and interpretation, write-up of the article and final approval for submission	made substantial contributions to the study conception and design, data collection, data analysis and interpretation, write-up of the article and final approval for submission	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
4348450	25750727	Justin Healy	2	made substantial contributions to the study conception and design, data collection, data analysis and interpretation, write-up of the article and final approval for submission	made substantial contributions to the study conception and design, data collection, data analysis and interpretation, write-up of the article and final approval for submission	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
4348450	25750727	Kohmal Solanki	2	made substantial contributions to data analysis and interpretation, write-up of the article and final approval for submission	made substantial contributions to data analysis and interpretation, write-up of the article and final approval for submission	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
4348450	25750727	Naim Kadoglou	2	made substantial contributions to the study conception and design, revising the article content and final approval for submission	made substantial contributions to the study conception and design, revising the article content and final approval for submission	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
4348450	25750727	Umar Ahmad	2	made substantial contributions to the study conception and design, data collection, data analysis and interpretation, write-up of the article and final approval for submission	made substantial contributions to the study conception and design, data collection, data analysis and interpretation, write-up of the article and final approval for submission	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
4403821	25894435	AJK	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4403821	25894435	AJK	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403821	25894435	CdG	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403821	25894435	HFV	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403821	25894435	HFV	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403821	25894435	HFV	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403821	25894435	JvO	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4403821	25894435	MJS	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403821	25894435	RL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403821	25894435	RL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403821	25894435	RL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403821	25894435	SMdM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403821	25894435	SMdM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4403821	25894435	SMdM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403821	25894435	SMdM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403821	25894435	SN	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4403821	25894435	SN	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4138415	25143778	GM	2	designed and conducted the study|edited the manuscript and drafted revisions	designed and conducted the study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4138415	25143778	GM	2	designed and conducted the study|edited the manuscript and drafted revisions	edited the manuscript and drafted revisions	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4138415	25143778	JD	2	designed and conducted the study|edited the manuscript and drafted revisions	designed and conducted the study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4138415	25143778	JD	2	designed and conducted the study|edited the manuscript and drafted revisions	edited the manuscript and drafted revisions	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4138415	25143778	ML	2	assisted with study design and data interpretation|edited the manuscript and drafted revisions	assisted with study design and data interpretation	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
4138415	25143778	ML	2	assisted with study design and data interpretation|edited the manuscript and drafted revisions	edited the manuscript and drafted revisions	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4138415	25143778	NL	2	designed and conducted the study|edited the manuscript and drafted revisions	designed and conducted the study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4138415	25143778	NL	2	designed and conducted the study|edited the manuscript and drafted revisions	edited the manuscript and drafted revisions	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4138415	25143778	ZA	2	conducted all statistical analyses, interpreted the findings and drafted the manuscript	conducted all statistical analyses, interpreted the findings and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5496959	28725232	AE	2	performed the experiments and wrote the ms	performed the experiments and wrote the ms	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5496959	28725232	MS	2	analyzed the data and wrote the ms	analyzed the data and wrote the ms	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5496959	28725232	SN	2	supervised the work and provided financial support	supervised the work and provided financial support	-	Funding acquisition|Supervision	YES
516769	15317656	EM	2	was responsible for mouse breeding and tissue preparation	was responsible for mouse breeding and tissue preparation	Performed the experiments	Investigation	YES
516769	15317656	ES	2	participated in the experimental design and analysis	participated in the experimental design and analysis	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
516769	15317656	GO	2	coordinated the study	coordinated the study	-	Project administration	YES
516769	15317656	JD	2	coordinated the study	coordinated the study	-	Project administration	YES
516769	15317656	JM	2	participated in experimental design	participated in experimental design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
516769	15317656	PCR	2	the drafting of the manuscript|study coordination	the drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
516769	15317656	PCR	2	the drafting of the manuscript|study coordination	study coordination	-	Project administration	YES
516769	15317656	RM	2	provided statistical support	provided statistical support	Analyzed the data	Formal analysis	YES
4355451	25830021	Adam Cristaudo	7	Study design, data collections, data analysis, writing. A/Prof. Pillay - Study design, writing	Study design, data collections, data analysis, writing. A/Prof. Pillay - Study design, writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology	YES
4355451	25830021	Sanjeev Naidu	7	Study design, writing	Study design, writing	Conceived and designed the experiments|Wrote the paper	Methodology	YES
4145833	25165483	All the authors	2	participated equally to the article	participated equally to the article	-	-	NO
4403822	25894574	GT	PLoS5	Conceived and designed the experiments|Wrote the paper|Performed theoretical analyses	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403822	25894574	GT	PLoS5	Conceived and designed the experiments|Wrote the paper|Performed theoretical analyses	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403822	25894574	GT	PLoS5	Conceived and designed the experiments|Wrote the paper|Performed theoretical analyses	Performed theoretical analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4403822	25894574	JA	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403822	25894574	JA	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403822	25894574	KA	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403822	25894574	KM	PLoS5	Wrote the paper|Performed theoretical analyses	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403822	25894574	KM	PLoS5	Wrote the paper|Performed theoretical analyses	Performed theoretical analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4403822	25894574	TS	PLoS5	Wrote the paper|Performed numerical experiments|Performed theoretical analyses	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403822	25894574	TS	PLoS5	Wrote the paper|Performed numerical experiments|Performed theoretical analyses	Performed numerical experiments	Performed the experiments	Formal analysis|Investigation	YES
4403822	25894574	TS	PLoS5	Wrote the paper|Performed numerical experiments|Performed theoretical analyses	Performed theoretical analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3249689	22216072	CS	2	participated in the design of the study, gathered data, and helped to draft and to revise the manuscript	participated in the design of the study, gathered data, and helped to draft and to revise the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
3249689	22216072	MBA	2	participated in the design of the study, gathered data, and helped to draft and to revise the manuscript	participated in the design of the study, gathered data, and helped to draft and to revise the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
3249689	22216072	PK	2	participated in the design of the study and helped to draft and to revise the manuscript	participated in the design of the study and helped to draft and to revise the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft|Writing - Review & Editing	YES
3249689	22216072	RKN	2	conceived the study, participated in the design of the study, and drafted and revised the manuscript	conceived the study, participated in the design of the study, and drafted and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5496963	28725235	ND	2	performed construction of vectors needed for the mutagenesis of two genes presented	performed construction of vectors needed for the mutagenesis of two genes presented	Performed the experiments	Investigation	YES
5496963	28725235	RS	2	performed construction of vectors needed for the mutagenesis of two genes presented	performed construction of vectors needed for the mutagenesis of two genes presented	Performed the experiments	Investigation	YES
5496963	28725235	SL	2	was involved in the analysis of t1 plants	was involved in the analysis of t1 plants	Performed the experiments	Investigation	YES
5496963	28725235	SO	2	designed and supervised the experiments, and wrote the manuscript	designed and supervised the experiments, and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Original Draft	YES
5496963	28725235	ZN	2	produced the gateway-compatible vector pmtn3164	produced the gateway-compatible vector pmtn3164	-	-	NO
516770	15333141	BJ	2	participated in development of concept and architecture and wrote the manuscript	participated in development of concept and architecture and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
516770	15333141	JA	2	programmed the perl objects and participated in development of concept and architecture of the software	programmed the perl objects and participated in development of concept and architecture of the software	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceptualization|Software	YES
516770	15333141	MG	2	supervised the project	supervised the project	-	Supervision	YES
4372641	25834731	DB	2	were involved in the clinical management, and in discussion of the case	were involved in the clinical management, and in discussion of the case	-	-	NO
4372641	25834731	JM	2	were involved in the clinical management, and in discussion of the case|was involved in the clinical management, undertook the review and prepared the manuscript	were involved in the clinical management, and in discussion of the case	-	-	NO
4372641	25834731	JM	2	were involved in the clinical management, and in discussion of the case|was involved in the clinical management, undertook the review and prepared the manuscript	was involved in the clinical management, undertook the review and prepared the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
4372641	25834731	SM	2	were involved in the clinical management, and in discussion of the case	were involved in the clinical management, and in discussion of the case	-	-	NO
4776057	26981580	A Staessen	2	constructed the flemengho database|wrote the first draft of the manuscript	constructed the flemengho database	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
4776057	26981580	A Staessen	2	constructed the flemengho database|wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
4776057	26981580	All authors	2	interpreted the results, commented on successive drafts of the manuscript, and approved the final version	interpreted the results, commented on successive drafts of the manuscript, and approved the final version	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4776057	26981580	E Lerut	2	advised on interpretation of the microcirculatory and renal phenotypes	advised on interpretation of the microcirculatory and renal phenotypes	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4776057	26981580	E Schutte	2	provided the south african data	provided the south african data	Contributed reagents/materials/analysis tools	Resources	YES
4776057	26981580	K Allegaert	2	advised on interpretation of the microcirculatory and renal phenotypes	advised on interpretation of the microcirculatory and renal phenotypes	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4776057	26981580	P Evenepoel	2	advised on interpretation of the microcirculatory and renal phenotypes	advised on interpretation of the microcirculatory and renal phenotypes	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4776057	26981580	P Verhamme	2	advised on interpretation of the microcirculatory and renal phenotypes	advised on interpretation of the microcirculatory and renal phenotypes	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4776057	26981580	R Schutte	2	provided the south african data	provided the south african data	Contributed reagents/materials/analysis tools	Resources	YES
4776057	26981580	W Smith	2	provided the south african data	provided the south african data	Contributed reagents/materials/analysis tools	Resources	YES
4403852	25893240	AG	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403852	25893240	BP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403852	25893240	BP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4403852	25893240	BP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403852	25893240	BP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403852	25893240	BP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403852	25893240	K. Bobrek	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4403852	25893240	K. Bobrek	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403852	25893240	K. Bobrek	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403852	25893240	K. Bobusia	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4403852	25893240	KM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4403852	25893240	LR	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403852	25893240	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403852	25893240	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4403852	25893240	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403852	25893240	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403852	25893240	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403852	25893240	TG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403852	25893240	TG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403852	25893240	TG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4452835	26078940	Bo Lin	2	contributed equally to this work	contributed equally to this work	-	-	NO
4452835	26078940	Mingyue Zhu	2	contributed equally to this work	contributed equally to this work	-	-	NO
4150425	25180041	GMO	2	carried out the immunological studies, acquired and performed the data analyses, and drafted the manuscript	carried out the immunological studies, acquired and performed the data analyses, and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4150425	25180041	JMM	2	conceived of the study, and participated in its design and coordination and drafted the manuscript	conceived of the study, and participated in its design and coordination and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
4150425	25180041	JNM	2	performed the clinical statistical analyses	performed the clinical statistical analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4150425	25180041	LS	2	carried out the immunological studies, acquired and performed the data analyses, and drafted the manuscript	carried out the immunological studies, acquired and performed the data analyses, and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4150425	25180041	SGD	2	performed the clinical design of the study	performed the clinical design of the study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4150425	25180041	TDB	2	participated in the design of the immunological studies, and provided technical expertise	participated in the design of the immunological studies, and provided technical expertise	Conceived and designed the experiments	Methodology	YES
4776071	26981578	A.B.	PLoS52	designed the study and wrote the manuscript|performed the experiments	designed the study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4776071	26981578	A.B.	PLoS52	designed the study and wrote the manuscript|performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
4776071	26981578	D.E.C.	PLoS52	performed the mouse transplantation experiments	performed the mouse transplantation experiments	Performed the experiments	Investigation	YES
4776071	26981578	I.C.M.	PLoS52	designed the study and wrote the manuscript	designed the study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4776071	26981578	L.G.	PLoS52	provided technical support and performed the automated microscope analysis	provided technical support and performed the automated microscope analysis	Performed the experiments	Investigation	YES
4776071	26981578	X.L.	PLoS52	performed the mouse transplantation experiments	performed the mouse transplantation experiments	Performed the experiments	Investigation	YES
5168813	27993127	LR	2	preparation of the manuscript	preparation of the manuscript	Wrote the paper	Writing - Original Draft	YES
5498472	28729876	AS	2	performed the experiment|contributed to analysis|designed the experiment and wrote and edit the manuscript	performed the experiment	Performed the experiments	Investigation	YES
5498472	28729876	AS	2	performed the experiment|contributed to analysis|designed the experiment and wrote and edit the manuscript	contributed to analysis	-	-	NO
5498472	28729876	AS	2	performed the experiment|contributed to analysis|designed the experiment and wrote and edit the manuscript	designed the experiment and wrote and edit the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5498472	28729876	DR	2	contributed to analysis	contributed to analysis	-	-	NO
5498472	28729876	JO	2	designed the experiment and wrote and edit the manuscript	designed the experiment and wrote and edit the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5498472	28729876	KW	2	performed the experiment	performed the experiment	Performed the experiments	Investigation	YES
5498472	28729876	PM	2	designed the experiment and wrote and edit the manuscript	designed the experiment and wrote and edit the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5498472	28729876	RL	2	performed the experiment	performed the experiment	Performed the experiments	Investigation	YES
5498472	28729876	SM	2	contributed to analysis	contributed to analysis	-	-	NO
5498472	28729876	SMM	2	contributed to analysis	contributed to analysis	-	-	NO
5498472	28729876	SS	2	performed the experiment	performed the experiment	Performed the experiments	Investigation	YES
4452836	26078942	Dan Xu	2	contributed equally to this work	contributed equally to this work	-	-	NO
4452836	26078942	Meng Wang	2	contributed equally to this work	contributed equally to this work	-	-	NO
4403853	25893426	AS	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403853	25893426	AS	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403853	25893426	BN	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4403853	25893426	BN	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4403853	25893426	CH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4403853	25893426	CH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403853	25893426	CH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403853	25893426	DZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403853	25893426	DZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4403853	25893426	DZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403853	25893426	DZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403853	25893426	JS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4403853	25893426	JS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4403853	25893426	KS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4403853	25893426	KS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403853	25893426	LZ	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4403853	25893426	LZ	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4403853	25893426	MCK	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4403853	25893426	MCK	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4403853	25893426	MR	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403853	25893426	MR	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403853	25893426	PJN	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403853	25893426	PJN	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4158765	25206924	BG	2	contributed to the conception and design of the study, coordinated efforts, drafted and revised the manuscript for important intellectual content	contributed to the conception and design of the study, coordinated efforts, drafted and revised the manuscript for important intellectual content	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft|Writing - Review & Editing	YES
4158765	25206924	KAF	2	participated in the studys design, discussed the results, helped to draft and revise the manuscript for important intellectual content	participated in the studys design, discussed the results, helped to draft and revise the manuscript for important intellectual content	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft|Writing - Review & Editing	YES
4158765	25206924	LC	2	acquired and revised the data	acquired and revised the data	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4158765	25206924	LV	2	contributed to the conception and design of the study, and performed the statistical analysis	contributed to the conception and design of the study, and performed the statistical analysis	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
4158765	25206924	PML	2	contributed to the conception and design of the study, and drafted the manuscript	contributed to the conception and design of the study, and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
4158765	25206924	RPW	2	participated in the studys design, discussed the results, helped to draft and revise the manuscript for important intellectual content	participated in the studys design, discussed the results, helped to draft and revise the manuscript for important intellectual content	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft|Writing - Review & Editing	YES
4158765	25206924	SWC	2	contributed to the conception and design of the study, acquired the data, and drafted the manuscript	contributed to the conception and design of the study, acquired the data, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Investigation|Methodology|Resources|Writing - Original Draft	YES
4158765	25206924	TT	2	acquired and revised the data	acquired and revised the data	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4158765	25206924	VGV	2	participated in the studys design and coordination and helped to draft the manuscript	participated in the studys design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft	YES
4776073	26981555	FK	7	acquisition and interpretation of c-triol data and revising the manuscript	acquisition and interpretation of c-triol data and revising the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
4776073	26981555	IDC	7	acquisition of data and revising the manuscript	acquisition of data and revising the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4776073	26981555	JR	7	acquisition and interpretation of data, drafting and revising the manuscript	acquisition and interpretation of data, drafting and revising the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
4776073	26981555	JW	7	acquisition of data and revising the manuscript	acquisition of data and revising the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4776073	26981555	MF	7	acquisition and interpretation of c-triol data and revising the manuscript	acquisition and interpretation of c-triol data and revising the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
4776073	26981555	MP	7	acquisition of data and revising the manuscript	acquisition of data and revising the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4776073	26981555	TM	7	supervising and design of the study, interpretation of data, and revising the manuscript	supervising and design of the study, interpretation of data, and revising the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Supervision|Writing - Review & Editing	YES
5168842	27993130	HCK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5168842	27993130	HCK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
5168842	27993130	HCK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5168842	27993130	HCK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5168842	27993130	LKY	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5168842	27993130	LKY	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5168842	27993130	LKY	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5168842	27993130	MLSS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5168842	27993130	MLSS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
5168842	27993130	MLSS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5168842	27993130	MLSS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5168842	27993130	PVL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5168842	27993130	PVL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
5168842	27993130	PVL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5168842	27993130	PVL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5168842	27993130	SBA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5168842	27993130	SBA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5168842	27993130	SBA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5168842	27993130	THH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5168842	27993130	THH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5168842	27993130	THH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5498473	28729868	AD	2	designed the study, interpreted data, wrote and revised manuscript	designed the study, interpreted data, wrote and revised manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5498473	28729868	JH	2	interpreted data, revised manuscript for intellectual content	interpreted data, revised manuscript for intellectual content	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5498473	28729868	JS	2	acquired and interpreted data, revised manuscript	acquired and interpreted data, revised manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
5498473	28729868	MM-H	2	designed experiment, acquired and interpreted data, revised manuscript	designed experiment, acquired and interpreted data, revised manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Review & Editing	YES
4403854	25894004	DK	PLoS5	Contributed reagents/materials/analysis tools|Analysis of evolutionary conservation data|Extraction of bacterial evolutionary conservation scores	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403854	25894004	DK	PLoS5	Contributed reagents/materials/analysis tools|Analysis of evolutionary conservation data|Extraction of bacterial evolutionary conservation scores	Analysis of evolutionary conservation data	Analyzed the data	Formal analysis	YES
4403854	25894004	DK	PLoS5	Contributed reagents/materials/analysis tools|Analysis of evolutionary conservation data|Extraction of bacterial evolutionary conservation scores	Extraction of bacterial evolutionary conservation scores	-	-	NO
4403854	25894004	ER	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403854	25894004	ER	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403854	25894004	OIA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403854	25894004	OIA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4403854	25894004	OIA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403854	25894004	OIA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403854	25894004	OIA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4167305	25237383	MDG	2	conceived and designed the study, directed the research, modified the figures for presentation and finalized the manuscript for submission	conceived and designed the study, directed the research, modified the figures for presentation and finalized the manuscript for submission	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Supervision|Visualization|Writing - Review & Editing	YES
4167305	25237383	MEG	2	processed samples, carried out the hla typing and collected some of the data presented in this manuscript	processed samples, carried out the hla typing and collected some of the data presented in this manuscript	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
4167305	25237383	SJP	2	carried out the research described in this manuscript, analyzed the data and contributed to drafting the manuscript	carried out the research described in this manuscript, analyzed the data and contributed to drafting the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4452837	26078974	All authors	2	have given approval to the final version of the paper	have given approval to the final version of the paper	-	-	NO
4388911	25859386	Emanuela Esposito	7	data collections, writing	data collections, writing	Performed the experiments|Wrote the paper	Investigation	YES
4388911	25859386	Emanuela Spadarella	7	data collections, writing	data collections, writing	Performed the experiments|Wrote the paper	Investigation	YES
4388911	25859386	Filomena Liccardo	7	data collection, reviewing draft	data collection, reviewing draft	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4388911	25859386	Gaetano Luglio	7	study design, data collections, data analysis, writing	study design, data collections, data analysis, writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology	YES
4388911	25859386	Giovanni Domenico De	7	study design, data analysis	study design, data analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
4388911	25859386	Luigi Bucci	7	study design, data collections, data analysis, writing	study design, data collections, data analysis, writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology	YES
4388911	25859386	Mariano Cesare Giglio	7	study design, data analysis, writing	study design, data analysis, writing	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology	YES
4388911	25859386	Rachele Tarquini	7	study design, data collections	study design, data collections	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4388911	25859386	Roberto Peltrini	7	data collection, reviewing draft	data collection, reviewing draft	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4388911	25859386	Viviana Sollazzo	7	data collection, data analysis, writing	data collection, data analysis, writing	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation	YES
517709	15331021	AKV	2	supervised and coordinated the computational and the experimental research as well as prepared the manuscript	supervised and coordinated the computational and the experimental research as well as prepared the manuscript	Wrote the paper	Formal analysis|Project administration|Supervision|Writing - Original Draft	YES
517709	15331021	AMS	2	supervised and coordinated the computational and the experimental research as well as prepared the manuscript	supervised and coordinated the computational and the experimental research as well as prepared the manuscript	Wrote the paper	Formal analysis|Project administration|Supervision|Writing - Original Draft	YES
517709	15331021	All authors	2	contributed to the manuscript and approved the final version	contributed to the manuscript and approved the final version	-	-	NO
517709	15331021	EMSA	2	beta-gal assays	beta-gal assays	Performed the experiments	Investigation	YES
517709	15331021	JRM	2	constructed the strains and contributed to the design of the chip experiment	constructed the strains and contributed to the design of the chip experiment	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
517709	15331021	RAO	2	did the bioinformatics analysis, and wrote programs facilitating primer design	did the bioinformatics analysis, and wrote programs facilitating primer design	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Software|Writing - Original Draft	YES
517709	15331021	VHN	2	carried out the chip experiments, and wrote parts of the first draft of the manuscript	carried out the chip experiments, and wrote parts of the first draft of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4228046	25391765	All authors	2	made significant contributions to the conception of the analyses, interpretation of the data and drafting of the manuscript	made significant contributions to the conception of the analyses, interpretation of the data and drafting of the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Resources|Writing - Original Draft	YES
4228046	25391765	E.W.	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
4228046	25391765	H.D.	2	conducted the statistical analyses	conducted the statistical analyses	Analyzed the data	Formal analysis	YES
4228046	25391765	K.H.	2	designed the study|drafted the first manuscript and incorporated suggestions from all co-authors	designed the study	Conceived and designed the experiments	Methodology	YES
4228046	25391765	K.H.	2	designed the study|drafted the first manuscript and incorporated suggestions from all co-authors	drafted the first manuscript and incorporated suggestions from all co-authors	Wrote the paper	Writing - Original Draft	YES
4228046	25391765	T.K.	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
4398819	25893094	A Royal	7	data collection, data analysis	data collection, data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4398819	25893094	B Collard	7	study design, writing	study design, writing	Conceived and designed the experiments|Wrote the paper	Methodology	YES
6066797	30073087	All authors	2	give their consent for publication	give their consent for publication	-	-	NO
6066797	30073087	All of the authors	2	played a key role in the analysis and interpretation of the cases	played a key role in the analysis and interpretation of the cases	Analyzed the data	Formal analysis	YES
6066797	30073087	MD	2	drafted the article and it was edited by the rest of the authors	drafted the article and it was edited by the rest of the authors	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6066797	30073087	MR	2	drafted the article and it was edited by the rest of the authors	drafted the article and it was edited by the rest of the authors	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6066797	30073087	MZ	2	drafted the article and it was edited by the rest of the authors	drafted the article and it was edited by the rest of the authors	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5498505	28729873	AS	2	have performed the experiments	have performed the experiments	Performed the experiments	Investigation	YES
5498505	28729873	LA	2	have performed the experiments	have performed the experiments	Performed the experiments	Investigation	YES
5498505	28729873	MJ	2	have performed the experiments	have performed the experiments	Performed the experiments	Investigation	YES
5498505	28729873	OS	2	have contributed in gc-ms analysis	have contributed in gc-ms analysis	-	-	NO
5498505	28729873	PCS	2	has done microscopy	has done microscopy	Performed the experiments	Investigation	YES
5498505	28729873	PSC	2	has done statistical analysis of the data	has done statistical analysis of the data	Analyzed the data	Formal analysis	YES
5498505	28729873	RD	2	have performed the experiments	have performed the experiments	Performed the experiments	Investigation	YES
5498505	28729873	RR	2	have performed the experiments	have performed the experiments	Performed the experiments	Investigation	YES
5498505	28729873	SG	2	have performed the experiments	have performed the experiments	Performed the experiments	Investigation	YES
5498505	28729873	SKR	2	conceived the idea for work	conceived the idea for work	Conceived and designed the experiments	Conceptualization	YES
5498505	28729873	SS	2	provided opium poppy plants and did hplc analysis	provided opium poppy plants and did hplc analysis	Performed the experiments	Investigation	YES
5498505	28729873	TT	2	have performed the experiments|have contributed in gc-ms analysis	have performed the experiments	Performed the experiments	Investigation	YES
5498505	28729873	TT	2	have performed the experiments|have contributed in gc-ms analysis	have contributed in gc-ms analysis	-	-	NO
4168991	25243015	GR	2	developed the concept	developed the concept	Conceived and designed the experiments	Conceptualization	YES
4168991	25243015	HW	2	developed the concept|conducted the statistical analysis	developed the concept	Conceived and designed the experiments	Conceptualization	YES
4168991	25243015	HW	2	developed the concept|conducted the statistical analysis	conducted the statistical analysis	Analyzed the data	Formal analysis	YES
4403856	25894652	AGC	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4403856	25894652	AGC	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4403856	25894652	BDM	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4403856	25894652	BDM	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4403856	25894652	JADA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403856	25894652	JADA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403856	25894652	JADA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403856	25894652	JWT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403856	25894652	JWT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4403856	25894652	JWT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403856	25894652	JWT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403856	25894652	ML	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4403856	25894652	ML	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4403856	25894652	NH	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4403856	25894652	NH	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4403856	25894652	SLC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403856	25894652	SLC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4403856	25894652	SLC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403856	25894652	SLC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403856	25894652	TL	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4403856	25894652	TL	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4403856	25894652	TW	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4403856	25894652	TW	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4816837	27077120	A.S.	2	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4816837	27077120	B.C.	2	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4816837	27077120	C.E.	2	performed the dietary assessment	performed the dietary assessment	Performed the experiments	Investigation	YES
4816837	27077120	G.S.	2	performed the proctology studies	performed the proctology studies	Performed the experiments	Investigation	YES
4816837	27077120	J.B.	2	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4816837	27077120	J.C.	2	performed the proctology studies	performed the proctology studies	Performed the experiments	Investigation	YES
4816837	27077120	M.N.	2	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4816837	27077120	P.B.	2	wrote the paper, which was reviewed, edited and approved by all authors	wrote the paper, which was reviewed, edited and approved by all authors	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4816837	27077120	P.N.	2	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4816837	27077120	R.P.	2	conceived and designed the study|wrote the paper, which was reviewed, edited and approved by all authors	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4816837	27077120	R.P.	2	conceived and designed the study|wrote the paper, which was reviewed, edited and approved by all authors	wrote the paper, which was reviewed, edited and approved by all authors	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5178093	28003017	DV	7	conceived and designed experimental study, made critical revisions on the manuscript	conceived and designed experimental study, made critical revisions on the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
5178093	28003017	EC	7	conceived and designed experimental study, made critical revisions on the manuscript	conceived and designed experimental study, made critical revisions on the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
5178093	28003017	EK	7	carried out experimental design and coordination, data analysis, drafted the manuscript	carried out experimental design and coordination, data analysis, drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Project administration|Writing - Original Draft	YES
5178093	28003017	JR	7	helped with animal handling and sample collection and revised the manuscript in a critical way	helped with animal handling and sample collection and revised the manuscript in a critical way	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5178093	28003017	RWL	7	carried out the rna seq study, collected raw data and performed statistical analysis, completed and revised the manuscript	carried out the rna seq study, collected raw data and performed statistical analysis, completed and revised the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
3458263	23028249	The authors	2	contributed equally to this work	contributed equally to this work	-	-	NO
4402385	25905016	JG	2	participated in the management of this patient, gained consent for use of images for publication of this case|also made large contributions to drafting this manuscript several times	participated in the management of this patient, gained consent for use of images for publication of this case	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
4402385	25905016	JG	2	participated in the management of this patient, gained consent for use of images for publication of this case|also made large contributions to drafting this manuscript several times	also made large contributions to drafting this manuscript several times	Wrote the paper	Writing - Original Draft	YES
4402385	25905016	KAS	2	lead initial drafts of the entire manuscript	lead initial drafts of the entire manuscript	Wrote the paper	Writing - Original Draft	YES
4402385	25905016	MMG	2	led the case write up and literature review overall	led the case write up and literature review overall	Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4402385	25905016	RB	2	led the care of this patient, advised on themes to cover for drafting and edited the manuscript on multiple occasions	led the care of this patient, advised on themes to cover for drafting and edited the manuscript on multiple occasions	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
4231462	25396724	EMF	2	wrote the first draft|critically read and revised subsequent versions	wrote the first draft	Wrote the paper	Writing - Original Draft	YES
4231462	25396724	EMF	2	wrote the first draft|critically read and revised subsequent versions	critically read and revised subsequent versions	Wrote the paper	Writing - Review & Editing	YES
4231462	25396724	FIB	2	critically read and revised subsequent versions	critically read and revised subsequent versions	Wrote the paper	Writing - Review & Editing	YES
5498511	28729875	BB	2	conducted the literature review and revised the paper	conducted the literature review and revised the paper	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
5498511	28729875	FZ	2	conducted the literature review and wrote the paper	conducted the literature review and wrote the paper	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5498511	28729875	M-HY	2	conducted the literature review, performed the computer simulation and revised the paper	conducted the literature review, performed the computer simulation and revised the paper	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
5498511	28729875	Y-BF	2	conceived of the research, conducted the literature review, performed the computer simulation and wrote the paper	conceived of the research, conducted the literature review, performed the computer simulation and wrote the paper	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
4403857	25894583	AM	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4403857	25894583	AM	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403857	25894583	ED	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4403857	25894583	ED	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403857	25894583	HP	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4403857	25894583	HP	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403857	25894583	JD	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403857	25894583	JD	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403857	25894583	JS	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4403857	25894583	JS	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403857	25894583	KW	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403857	25894583	KW	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403857	25894583	MB	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403857	25894583	MB	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403857	25894583	MK	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4403857	25894583	MK	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403857	25894583	MM	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403857	25894583	MM	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403857	25894583	SA	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403857	25894583	SA	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403857	25894583	TN	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403857	25894583	TN	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403857	25894583	TR	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403857	25894583	TR	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403857	25894583	WK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403857	25894583	WK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403857	25894583	WK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404414	25905017	AES	2	were responsible for analysis and interpretation of data|were responsible for drafting the article	were responsible for analysis and interpretation of data	Analyzed the data	Formal analysis	YES
4404414	25905017	AES	2	were responsible for analysis and interpretation of data|were responsible for drafting the article	were responsible for drafting the article	Wrote the paper	Writing - Original Draft	YES
4404414	25905017	All authors	2	were responsible for final approval of the version to be published	were responsible for final approval of the version to be published	-	-	NO
4404414	25905017	IAH	2	were responsible for drafting the article	were responsible for drafting the article	Wrote the paper	Writing - Original Draft	YES
4404414	25905017	RKP	2	were responsible for analysis and interpretation of data|were responsible for drafting the article	were responsible for analysis and interpretation of data	Analyzed the data	Formal analysis	YES
4404414	25905017	RKP	2	were responsible for analysis and interpretation of data|were responsible for drafting the article	were responsible for drafting the article	Wrote the paper	Writing - Original Draft	YES
517929	15345031	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
517929	15345031	CP	2	read the manuscript and provided comments	read the manuscript and provided comments	-	-	NO
517929	15345031	GW	2	helped with the experimental design and was responsible for generating all of the genechip data as well as editing the manuscript	helped with the experimental design and was responsible for generating all of the genechip data as well as editing the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
517929	15345031	HIC	2	protein isoform p32 0	protein isoform p32 0	Performed the experiments	Investigation	YES
517929	15345031	IX	2	alpha 3 2	alpha 3 2	-	-	NO
517929	15345031	JA	2	provided guidance with the statistical power analysis and additions to the manuscript	provided guidance with the statistical power analysis and additions to the manuscript	Analyzed the data	Formal analysis|Supervision	YES
517929	15345031	RL	2	designed, conducted, and analyzed the quantitative pcr experiments, performed bioinformatics support, and edited the manuscript	designed, conducted, and analyzed the quantitative pcr experiments, performed bioinformatics support, and edited the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Review & Editing	YES
517929	15345031	RS	2	planned and designed the study, conducted the micoarray experiments with the codelink platform, analyzed the data, generated all of the figures, and drafted the paper	planned and designed the study, conducted the micoarray experiments with the codelink platform, analyzed the data, generated all of the figures, and drafted the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Data curation|Formal analysis|Investigation|Methodology|Visualization|Writing - Original Draft	YES
517929	15345031	TJS	2	helped with writing of the paper, deriving the overlap between platforms, provided overall technical guidance and coordination	helped with writing of the paper, deriving the overlap between platforms, provided overall technical guidance and coordination	Wrote the paper	Project administration|Supervision|Writing - Original Draft	YES
517929	15345031	TK-K	2	edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
517929	15345031	VI	2	alpha 3, transcript variant 1 -4	alpha 3, transcript variant 1 -4	-	-	NO
517929	15345031	VIIa	2	polypeptide 2 like 1	polypeptide 2 like 1	Performed the experiments	Investigation	YES
6106189	30151212	All authors	2	revised and approved the final version of the manuscript and agreed to be accountable for all aspects of the work	revised and approved the final version of the manuscript and agreed to be accountable for all aspects of the work	Wrote the paper	Writing - Review & Editing	YES
6106189	30151212	C.H.	2	contributed to data acquisition, analysis, or interpretation|drafted the work or revised it critically	contributed to data acquisition, analysis, or interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6106189	30151212	C.H.	2	contributed to data acquisition, analysis, or interpretation|drafted the work or revised it critically	drafted the work or revised it critically	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6106189	30151212	H.Z.	2	designed the study|contributed to data acquisition, analysis, or interpretation|drafted the work or revised it critically	designed the study	Conceived and designed the experiments	Methodology	YES
6106189	30151212	H.Z.	2	designed the study|contributed to data acquisition, analysis, or interpretation|drafted the work or revised it critically	contributed to data acquisition, analysis, or interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6106189	30151212	H.Z.	2	designed the study|contributed to data acquisition, analysis, or interpretation|drafted the work or revised it critically	drafted the work or revised it critically	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6106189	30151212	J.M.	2	designed the study|contributed to data acquisition, analysis, or interpretation|drafted the work or revised it critically	designed the study	Conceived and designed the experiments	Methodology	YES
6106189	30151212	J.M.	2	designed the study|contributed to data acquisition, analysis, or interpretation|drafted the work or revised it critically	contributed to data acquisition, analysis, or interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6106189	30151212	J.M.	2	designed the study|contributed to data acquisition, analysis, or interpretation|drafted the work or revised it critically	drafted the work or revised it critically	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6106189	30151212	K.B.	2	designed the study|contributed to data acquisition, analysis, or interpretation|drafted the work or revised it critically	designed the study	Conceived and designed the experiments	Methodology	YES
6106189	30151212	K.B.	2	designed the study|contributed to data acquisition, analysis, or interpretation|drafted the work or revised it critically	contributed to data acquisition, analysis, or interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6106189	30151212	K.B.	2	designed the study|contributed to data acquisition, analysis, or interpretation|drafted the work or revised it critically	drafted the work or revised it critically	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6106189	30151212	L.H.	2	contributed to data acquisition, analysis, or interpretation	contributed to data acquisition, analysis, or interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6106189	30151212	S.O.	2	designed the study|contributed to data acquisition, analysis, or interpretation|drafted the work or revised it critically	designed the study	Conceived and designed the experiments	Methodology	YES
6106189	30151212	S.O.	2	designed the study|contributed to data acquisition, analysis, or interpretation|drafted the work or revised it critically	contributed to data acquisition, analysis, or interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6106189	30151212	S.O.	2	designed the study|contributed to data acquisition, analysis, or interpretation|drafted the work or revised it critically	drafted the work or revised it critically	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6106189	30151212	V.D.	2	designed the study|contributed to data acquisition, analysis, or interpretation|drafted the work or revised it critically	designed the study	Conceived and designed the experiments	Methodology	YES
6106189	30151212	V.D.	2	designed the study|contributed to data acquisition, analysis, or interpretation|drafted the work or revised it critically	contributed to data acquisition, analysis, or interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6106189	30151212	V.D.	2	designed the study|contributed to data acquisition, analysis, or interpretation|drafted the work or revised it critically	drafted the work or revised it critically	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6106189	30151212	V.W.	2	contributed to data acquisition, analysis, or interpretation|drafted the work or revised it critically	contributed to data acquisition, analysis, or interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6106189	30151212	V.W.	2	contributed to data acquisition, analysis, or interpretation|drafted the work or revised it critically	drafted the work or revised it critically	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4233212	25399543	AG	2	developed the methods for the trial and for completion of data collection	developed the methods for the trial and for completion of data collection	Performed the experiments	Investigation|Methodology	YES
4233212	25399543	CJCG	2	contributed to developing the methods, developing data collection protocols for baseline, and revising the report	contributed to developing the methods, developing data collection protocols for baseline, and revising the report	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources	YES
4233212	25399543	CK	2	developed the methods for the trial and for completion of data collection	developed the methods for the trial and for completion of data collection	Performed the experiments	Investigation|Methodology	YES
4233212	25399543	DO	2	developed the methods for the trial and for completion of data collection	developed the methods for the trial and for completion of data collection	Performed the experiments	Investigation|Methodology	YES
4233212	25399543	FBH	2	contributed to developing the methods, developing data collection protocols for baseline, and revising the report	contributed to developing the methods, developing data collection protocols for baseline, and revising the report	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources	YES
4233212	25399543	KHM	2	developed the methods for the trial and for completion of data collection	developed the methods for the trial and for completion of data collection	Performed the experiments	Investigation|Methodology	YES
4233212	25399543	LJF	2	contributed to developing the methods, developing data collection protocols for baseline, and revising the report	contributed to developing the methods, developing data collection protocols for baseline, and revising the report	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources	YES
4233212	25399543	OG	2	developed the original idea to conduct a randomized control pilot|developed the methods for the trial and for completion of data collection|conducted data analysis, and they drafted and revised the manuscript with comments from all authors	developed the original idea to conduct a randomized control pilot	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
4233212	25399543	OG	2	developed the original idea to conduct a randomized control pilot|developed the methods for the trial and for completion of data collection|conducted data analysis, and they drafted and revised the manuscript with comments from all authors	developed the methods for the trial and for completion of data collection	Performed the experiments	Investigation|Methodology	YES
4233212	25399543	OG	2	developed the original idea to conduct a randomized control pilot|developed the methods for the trial and for completion of data collection|conducted data analysis, and they drafted and revised the manuscript with comments from all authors	conducted data analysis, and they drafted and revised the manuscript with comments from all authors	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
4233212	25399543	SBA	2	contributed to developing the methods, developing data collection protocols for baseline, and revising the report	contributed to developing the methods, developing data collection protocols for baseline, and revising the report	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources	YES
4233212	25399543	SGSR	2	developed the original idea to conduct a randomized control pilot|developed the methods for the trial and for completion of data collection|conducted data analysis, and they drafted and revised the manuscript with comments from all authors	developed the original idea to conduct a randomized control pilot	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
4233212	25399543	SGSR	2	developed the original idea to conduct a randomized control pilot|developed the methods for the trial and for completion of data collection|conducted data analysis, and they drafted and revised the manuscript with comments from all authors	developed the methods for the trial and for completion of data collection	Performed the experiments	Investigation|Methodology	YES
4233212	25399543	SGSR	2	developed the original idea to conduct a randomized control pilot|developed the methods for the trial and for completion of data collection|conducted data analysis, and they drafted and revised the manuscript with comments from all authors	conducted data analysis, and they drafted and revised the manuscript with comments from all authors	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
4405003	25905014	Davut Akduman	2	author, study design, data collections, data analysis, writing	author, study design, data collections, data analysis, writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology	YES
4405003	25905014	Fevzi Solmaz	2	co-author data collections, writing, referring the patients	co-author data collections, writing, referring the patients	Performed the experiments|Wrote the paper	Investigation	YES
4405003	25905014	MD	2	author, study design, data collections, data analysis, writing|author, study design, data collections, data analysis, writing|co-author, data collections, writing|co-author, data collections, writing|co-author, data collections, referring the patients|co-author data collections, writing, referring the patients	author, study design, data collections, data analysis, writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology	YES
4405003	25905014	MD	2	author, study design, data collections, data analysis, writing|author, study design, data collections, data analysis, writing|co-author, data collections, writing|co-author, data collections, writing|co-author, data collections, referring the patients|co-author data collections, writing, referring the patients	author, study design, data collections, data analysis, writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology	YES
4405003	25905014	MD	2	author, study design, data collections, data analysis, writing|author, study design, data collections, data analysis, writing|co-author, data collections, writing|co-author, data collections, writing|co-author, data collections, referring the patients|co-author data collections, writing, referring the patients	co-author, data collections, writing	Performed the experiments|Wrote the paper	Investigation	YES
4405003	25905014	MD	2	author, study design, data collections, data analysis, writing|author, study design, data collections, data analysis, writing|co-author, data collections, writing|co-author, data collections, writing|co-author, data collections, referring the patients|co-author data collections, writing, referring the patients	co-author, data collections, writing	Performed the experiments|Wrote the paper	Investigation	YES
4405003	25905014	MD	2	author, study design, data collections, data analysis, writing|author, study design, data collections, data analysis, writing|co-author, data collections, writing|co-author, data collections, writing|co-author, data collections, referring the patients|co-author data collections, writing, referring the patients	co-author, data collections, referring the patients	Performed the experiments	Investigation	YES
4405003	25905014	MD	2	author, study design, data collections, data analysis, writing|author, study design, data collections, data analysis, writing|co-author, data collections, writing|co-author, data collections, writing|co-author, data collections, referring the patients|co-author data collections, writing, referring the patients	co-author data collections, writing, referring the patients	Performed the experiments|Wrote the paper	Investigation	YES
4405003	25905014	Mehmet Haksever	2	author, study design, data collections, data analysis, writing	author, study design, data collections, data analysis, writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology	YES
4405003	25905014	Muhammed Yanilmaz	2	co-author, data collections, referring the patients	co-author, data collections, referring the patients	Performed the experiments	Investigation	YES
4405003	25905014	Mustafa Demir	2	co-author, data collections, writing	co-author, data collections, writing	Performed the experiments|Wrote the paper	Investigation	YES
4405003	25905014	Sundus Aslan	2	co-author, data collections, writing	co-author, data collections, writing	Performed the experiments|Wrote the paper	Investigation	YES
5498513	28729869	CI	2	obtained and analyzed microsatellite data	obtained and analyzed microsatellite data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5498513	28729869	FP	2	conceived and designed the study, analyzed and interpreted data, and wrote the paper	conceived and designed the study, analyzed and interpreted data, and wrote the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
5498513	28729869	GP	2	obtained and analyzed microsatellite data	obtained and analyzed microsatellite data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5498513	28729869	LH	2	designed the study and interpreted data	designed the study and interpreted data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5498513	28729869	MC	2	obtained and analyzed microsatellite data	obtained and analyzed microsatellite data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5498513	28729869	PM	2	performed niche modeling analysis	performed niche modeling analysis	Performed the experiments	Investigation|Methodology	YES
4403863	25894202	EK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4403863	25894202	JK	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4403863	25894202	JK	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4403863	25894202	JK	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403863	25894202	LM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4403863	25894202	LM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4403863	25894202	LM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403863	25894202	LR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403863	25894202	LR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4403863	25894202	LR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403863	25894202	LR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403863	25894202	LR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403863	25894202	MS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4403863	25894202	MS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4403863	25894202	MT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403863	25894202	MT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4403863	25894202	MT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403863	25894202	MT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403863	25894202	MT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403863	25894202	VS	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403863	25894202	VS	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4403863	25894202	VS	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403863	25894202	ZK	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4403863	25894202	ZK	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4403863	25894202	ZK	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403863	25894202	ZW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405004	25905015	Hubert Schelzigand Mansur	2	helped to draft the manuscript|participated in conceiving and designing the manuscript	helped to draft the manuscript	Wrote the paper	Writing - Original Draft	YES
4405004	25905015	Hubert Schelzigand Mansur	2	helped to draft the manuscript|participated in conceiving and designing the manuscript	participated in conceiving and designing the manuscript	Conceived and designed the experiments	Conceptualization	YES
4405004	25905015	Katharina B. Herma	2	collected the data and analysed them|contributed substantially to the statistical analysis	collected the data and analysed them	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4405004	25905015	Katharina B. Herma	2	collected the data and analysed them|contributed substantially to the statistical analysis	contributed substantially to the statistical analysis	Analyzed the data	Formal analysis	YES
4405004	25905015	Markus U. Wagenhauser	2	contributed substantially to the conception and design of the manuscript|drafted the article and revised it critically	contributed substantially to the conception and design of the manuscript	Conceived and designed the experiments	Conceptualization	YES
4405004	25905015	Markus U. Wagenhauser	2	contributed substantially to the conception and design of the manuscript|drafted the article and revised it critically	drafted the article and revised it critically	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4405004	25905015	Philip Dueppers	2	helped to improve the quality of the manuscript by revising it critically, and contributed designing the figures and tables	helped to improve the quality of the manuscript by revising it critically, and contributed designing the figures and tables	Conceived and designed the experiments|Wrote the paper	Visualization|Writing - Review & Editing	YES
4405004	25905015	Tolga A. Sagban	2	helped to write the article and contributed to its design|participated in essential data interpretation	helped to write the article and contributed to its design	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
4405004	25905015	Tolga A. Sagban	2	helped to write the article and contributed to its design|participated in essential data interpretation	participated in essential data interpretation	Analyzed the data	Formal analysis	YES
4236629	25406951	ON	2	assisted with the data analysis and manuscript preparation	assisted with the data analysis and manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4236629	25406951	QAK	2	was responsible for the conceptualization, analysis and preparation of this manuscript	was responsible for the conceptualization, analysis and preparation of this manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4236629	25406951	RP	2	was responsible for the conceptualization, design, data collection, and analysis and manuscript preparation	was responsible for the conceptualization, design, data collection, and analysis and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
4403867	25894314	AK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403867	25894314	AK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403867	25894314	AK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403867	25894314	AK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403867	25894314	AS	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403867	25894314	DD	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Collected the samples	Performed the experiments	Performed the experiments	Investigation	YES
4403867	25894314	DD	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Collected the samples	Analyzed the data	Analyzed the data	Formal analysis	YES
4403867	25894314	DD	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Collected the samples	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403867	25894314	DD	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Collected the samples	Collected the samples	Performed the experiments	Investigation	YES
4403867	25894314	DS	PLoS5	Performed the experiments|Collected the samples	Performed the experiments	Performed the experiments	Investigation	YES
4403867	25894314	DS	PLoS5	Performed the experiments|Collected the samples	Collected the samples	Performed the experiments	Investigation	YES
4403867	25894314	GM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4403867	25894314	JR	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4403867	25894314	SL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4403867	25894314	SL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4403867	25894314	SL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
520745	15347431	AD	2	contributed to fish screening, line establishment and to scientific descriptions of these lines|to gfp expression and in situ analysis	contributed to fish screening, line establishment and to scientific descriptions of these lines	Performed the experiments	Investigation	YES
520745	15347431	AD	2	contributed to fish screening, line establishment and to scientific descriptions of these lines|to gfp expression and in situ analysis	to gfp expression and in situ analysis	Performed the experiments	Investigation	YES
520745	15347431	DB	2	contributed to fish screening, line establishment and to scientific descriptions of these lines|to molecular analysis|to gfp expression and in situ analysis|designed and built the transposons used in this study and was responsible for drafting the manuscript for publication	contributed to fish screening, line establishment and to scientific descriptions of these lines	Performed the experiments	Investigation	YES
520745	15347431	DB	2	contributed to fish screening, line establishment and to scientific descriptions of these lines|to molecular analysis|to gfp expression and in situ analysis|designed and built the transposons used in this study and was responsible for drafting the manuscript for publication	to molecular analysis	Performed the experiments	Investigation	YES
520745	15347431	DB	2	contributed to fish screening, line establishment and to scientific descriptions of these lines|to molecular analysis|to gfp expression and in situ analysis|designed and built the transposons used in this study and was responsible for drafting the manuscript for publication	to gfp expression and in situ analysis	Performed the experiments	Investigation	YES
520745	15347431	DB	2	contributed to fish screening, line establishment and to scientific descriptions of these lines|to molecular analysis|to gfp expression and in situ analysis|designed and built the transposons used in this study and was responsible for drafting the manuscript for publication	designed and built the transposons used in this study and was responsible for drafting the manuscript for publication	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
520745	15347431	SE	2	conceived and supervised the study and edited the manuscript	conceived and supervised the study and edited the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Supervision|Writing - Review & Editing	YES
520745	15347431	SH	2	contributed to fish screening, line establishment and to scientific descriptions of these lines	contributed to fish screening, line establishment and to scientific descriptions of these lines	Performed the experiments	Investigation	YES
520745	15347431	SS	2	to molecular analysis	to molecular analysis	Performed the experiments	Investigation	YES
520745	15347431	ZW	2	contributed to fish screening, line establishment and to scientific descriptions of these lines	contributed to fish screening, line establishment and to scientific descriptions of these lines	Performed the experiments	Investigation	YES
5498514	28729870	JE	2	collected measurements and wrote the article	collected measurements and wrote the article	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5498514	28729870	MK	2	collected and analyzed data	collected and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5498514	28729870	MS	2	collected data, analyzed data and supervised the writing of the manuscript	collected data, analyzed data and supervised the writing of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Supervision|Writing - Original Draft	YES
4412911	25941568	Carlos Alfredo Bautista	2	data collection and analysis	data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4412911	25941568	Eliseo Navarro Muniz	2	data collection and analysis	data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4901368	27074285	C.T.L.	2	contributed equally to this work	contributed equally to this work	-	-	NO
4901368	27074285	J.R.W.	2	contributed equally to this work	contributed equally to this work	-	-	NO
4421108	25973190	Caldeira Fradique	7	Reviewed the paper and data analysis	Reviewed the paper and data analysis	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4421108	25973190	Carlos Cardoso	7	Reviewed the paper, data analysis and provided expert advice regarding radiological examinations	Reviewed the paper, data analysis and provided expert advice regarding radiological examinations	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
4421108	25973190	Celso Nabais	7	Case report design, data analysis and wrote the paper. Raquel Salustio; Franciso V Sousa, Eusebio Porto	Case report design, data analysis and wrote the paper. Raquel Salustio; Franciso V Sousa, Eusebio Porto	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4403875	25894612	CL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403875	25894612	CL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4403875	25894612	CL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403875	25894612	CL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403875	25894612	CL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403875	25894612	DJK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403875	25894612	DJK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4403875	25894612	DJK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403875	25894612	DJK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403875	25894612	DJK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403875	25894612	GRM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403875	25894612	GRM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403875	25894612	GRM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403875	25894612	JWP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403875	25894612	JWP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403875	25894612	JWP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403875	25894612	JWP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403875	25894612	ZF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403875	25894612	ZF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4403875	25894612	ZF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4403875	25894612	ZF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4238965	25413893	ADL	2	conducted sequence and statistical analysis|critically revised the manuscript	conducted sequence and statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4238965	25413893	ADL	2	conducted sequence and statistical analysis|critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4238965	25413893	DK	2	supervised study procedures|critically revised the manuscript	supervised study procedures	Performed the experiments	Investigation|Supervision	YES
4238965	25413893	DK	2	supervised study procedures|critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4238965	25413893	FM	2	conducted laboratory assays	conducted laboratory assays	Performed the experiments	Investigation	YES
4238965	25413893	JH	2	conducted sequence and statistical analysis|critically revised the manuscript	conducted sequence and statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4238965	25413893	JH	2	conducted sequence and statistical analysis|critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4238965	25413893	LD	2	designed the study protocol|supervised study procedures|critically revised the manuscript	designed the study protocol	Conceived and designed the experiments	Methodology	YES
4238965	25413893	LD	2	designed the study protocol|supervised study procedures|critically revised the manuscript	supervised study procedures	Performed the experiments	Investigation|Supervision	YES
4238965	25413893	LD	2	designed the study protocol|supervised study procedures|critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4238965	25413893	LK	2	supervised study procedures	supervised study procedures	Performed the experiments	Investigation|Supervision	YES
4238965	25413893	LS	2	conducted laboratory assays|conducted sequence and statistical analysis	conducted laboratory assays	Performed the experiments	Investigation	YES
4238965	25413893	LS	2	conducted laboratory assays|conducted sequence and statistical analysis	conducted sequence and statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4238965	25413893	MB	2	conducted laboratory assays|conducted sequence and statistical analysis|critically revised the manuscript	conducted laboratory assays	Performed the experiments	Investigation	YES
4238965	25413893	MB	2	conducted laboratory assays|conducted sequence and statistical analysis|critically revised the manuscript	conducted sequence and statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4238965	25413893	MB	2	conducted laboratory assays|conducted sequence and statistical analysis|critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4238965	25413893	NB	2	supervised study procedures	supervised study procedures	Performed the experiments	Investigation|Supervision	YES
4238965	25413893	RK	2	conceived the study and was responsible for all its aspects|designed the study protocol|conducted sequence and statistical analysis|wrote the first draft of the manuscript and worked with co-authors to finalize the writing|critically revised the manuscript	conceived the study and was responsible for all its aspects	Conceived and designed the experiments	Conceptualization	YES
4238965	25413893	RK	2	conceived the study and was responsible for all its aspects|designed the study protocol|conducted sequence and statistical analysis|wrote the first draft of the manuscript and worked with co-authors to finalize the writing|critically revised the manuscript	designed the study protocol	Conceived and designed the experiments	Methodology	YES
4238965	25413893	RK	2	conceived the study and was responsible for all its aspects|designed the study protocol|conducted sequence and statistical analysis|wrote the first draft of the manuscript and worked with co-authors to finalize the writing|critically revised the manuscript	conducted sequence and statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4238965	25413893	RK	2	conceived the study and was responsible for all its aspects|designed the study protocol|conducted sequence and statistical analysis|wrote the first draft of the manuscript and worked with co-authors to finalize the writing|critically revised the manuscript	wrote the first draft of the manuscript and worked with co-authors to finalize the writing	Performed the experiments|Wrote the paper	Writing - Original Draft	YES
4238965	25413893	RK	2	conceived the study and was responsible for all its aspects|designed the study protocol|conducted sequence and statistical analysis|wrote the first draft of the manuscript and worked with co-authors to finalize the writing|critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4238965	25413893	RML	2	conducted laboratory assays|critically revised the manuscript	conducted laboratory assays	Performed the experiments	Investigation	YES
4238965	25413893	RML	2	conducted laboratory assays|critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4238965	25413893	SM	2	conducted laboratory assays	conducted laboratory assays	Performed the experiments	Investigation	YES
4238965	25413893	WI	2	supervised study procedures	supervised study procedures	Performed the experiments	Investigation|Supervision	YES
520746	15355549	BOP	2	conceived the study, participated in its design and coordination, and assisted with manuscript preparation	conceived the study, participated in its design and coordination, and assisted with manuscript preparation	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
520746	15355549	PF	2	designed the study and conducted the growth experiments and revised the manuscript	designed the study and conducted the growth experiments and revised the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
4454716	26078955	Chunlin Jiang	2	contributed equally to this study	contributed equally to this study	-	-	NO
4454716	26078955	Jianting Long	2	contributed equally to this study	contributed equally to this study	-	-	NO
4909368	27322477	AJ	2	were responsible in large part for performing the studies reported herein and participated in the design, execution, and interpretation of the data|were responsible for conception, design, oversight, execution, and interpretation of the data for this study	were responsible in large part for performing the studies reported herein and participated in the design, execution, and interpretation of the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
4909368	27322477	AJ	2	were responsible in large part for performing the studies reported herein and participated in the design, execution, and interpretation of the data|were responsible for conception, design, oversight, execution, and interpretation of the data for this study	were responsible for conception, design, oversight, execution, and interpretation of the data for this study	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation|Methodology|Supervision	YES
4909368	27322477	AMC	2	were responsible for conception, design, oversight, execution, and interpretation of the data for this study	were responsible for conception, design, oversight, execution, and interpretation of the data for this study	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation|Methodology|Supervision	YES
4909368	27322477	All authors	2	contributed to the drafts, writing, figure preparation and editing of the final manuscript	contributed to the drafts, writing, figure preparation and editing of the final manuscript	Wrote the paper	Visualization|Writing - Original Draft|Writing - Review & Editing	YES
4909368	27322477	DN	2	were responsible for the recruitment and classification of study subjects as well as the procurement of tissue samples	were responsible for the recruitment and classification of study subjects as well as the procurement of tissue samples	Performed the experiments	Investigation	YES
4909368	27322477	JCC	2	were responsible in large part for performing the studies reported herein and participated in the design, execution, and interpretation of the data	were responsible in large part for performing the studies reported herein and participated in the design, execution, and interpretation of the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
4909368	27322477	JEC	2	were responsible in large part for performing the studies reported herein and participated in the design, execution, and interpretation of the data	were responsible in large part for performing the studies reported herein and participated in the design, execution, and interpretation of the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
4909368	27322477	JMW	2	were responsible for the recruitment and classification of study subjects as well as the procurement of tissue samples	were responsible for the recruitment and classification of study subjects as well as the procurement of tissue samples	Performed the experiments	Investigation	YES
4909368	27322477	MD	2	were responsible for the recruitment and classification of study subjects as well as the procurement of tissue samples	were responsible for the recruitment and classification of study subjects as well as the procurement of tissue samples	Performed the experiments	Investigation	YES
4909368	27322477	MH	2	were responsible for the recruitment and classification of study subjects as well as the procurement of tissue samples	were responsible for the recruitment and classification of study subjects as well as the procurement of tissue samples	Performed the experiments	Investigation	YES
4909368	27322477	RC	2	were responsible for conception, design, oversight, execution, and interpretation of the data for this study	were responsible for conception, design, oversight, execution, and interpretation of the data for this study	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation|Methodology|Supervision	YES
4909368	27322477	VP	2	were responsible for the recruitment and classification of study subjects as well as the procurement of tissue samples	were responsible for the recruitment and classification of study subjects as well as the procurement of tissue samples	Performed the experiments	Investigation	YES
5498517	28729872	All of the authors	PLoS52	analyzed the results and approved the final version of the manuscript	analyzed the results and approved the final version of the manuscript	Analyzed the data	Formal analysis	YES
5498517	28729872	HQ	PLoS52	wrote paper and designed and analyzed the experiments	wrote paper and designed and analyzed the experiments	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5498517	28729872	SZ	PLoS52	designed the part of experiments	designed the part of experiments	Conceived and designed the experiments	Methodology	YES
5498517	28729872	YG	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5498517	28729872	YW	PLoS52	designed the experiment and collected the pollen and done the physiology experiments and revised the manuscript	designed the experiment and collected the pollen and done the physiology experiments and revised the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
4240851	25416416	F Cotton	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4240851	25416416	Helena Rabie	2	gave input, reviewed the manuscript and approved the final version	gave input, reviewed the manuscript and approved the final version	Wrote the paper	Writing - Review & Editing	YES
4421109	25973191	HB	2	participated in the writing of the manuscript	participated in the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
4421109	25973191	JBC	2	participated in the conception, design, writing and editing of this study	participated in the conception, design, writing and editing of this study	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
4421109	25973191	MJG	2	participated in the writing of the manuscript	participated in the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
4421109	25973191	NB	2	participated in the writing of the manuscript	participated in the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
4421109	25973191	RSV	2	participated in the conception, design, writing and editing of this study|participated in the statistical analysis|is the guarantor	participated in the conception, design, writing and editing of this study	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
4421109	25973191	RSV	2	participated in the conception, design, writing and editing of this study|participated in the statistical analysis|is the guarantor	participated in the statistical analysis	Analyzed the data	Formal analysis	YES
4421109	25973191	RSV	2	participated in the conception, design, writing and editing of this study|participated in the statistical analysis|is the guarantor	is the guarantor	-	-	NO
4403877	25893833	BL	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403877	25893833	HTY	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4403877	25893833	PZ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403877	25893833	PZ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403877	25893833	PZ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403877	25893833	ZHZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
6141511	30237892	Oguro A. Wrote	5	or contributed to the writing of the manuscript: Oguro A	or contributed to the writing of the manuscript: Oguro A	Wrote the paper	Writing - Original Draft	YES
4454717	26078961	Juanping Qiu	2	contributed equally to this work	contributed equally to this work	-	-	NO
4454717	26078961	Zhiliang Yu	2	contributed equally to this work	contributed equally to this work	-	-	NO
520814	15380028	ALK	2	were involved in the data analysis and the manuscript edition	were involved in the data analysis and the manuscript edition	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
520814	15380028	BG	2	were involved in the data analysis and the manuscript edition	were involved in the data analysis and the manuscript edition	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
520814	15380028	CCW	2	were involved in the microarray production and the manuscript edition	were involved in the microarray production and the manuscript edition	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
520814	15380028	CS	2	were involved in the microarray production and the manuscript edition	were involved in the microarray production and the manuscript edition	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
520814	15380028	DC	2	provided the tumor samples and patient information and were also involved in the manuscript edition	provided the tumor samples and patient information and were also involved in the manuscript edition	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Review & Editing	YES
520814	15380028	FB	2	provided the tumor samples and patient information and were also involved in the manuscript edition	provided the tumor samples and patient information and were also involved in the manuscript edition	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Review & Editing	YES
520814	15380028	FW	2	provided the tumor samples and patient information and were also involved in the manuscript edition	provided the tumor samples and patient information and were also involved in the manuscript edition	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Review & Editing	YES
520814	15380028	JK	2	principal investigator of the project, participated in its design and is the final editor of the manuscript	principal investigator of the project, participated in its design and is the final editor of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Funding acquisition|Methodology|Writing - Review & Editing	YES
520814	15380028	JSW	2	were involved in the microarray production and the manuscript edition	were involved in the microarray production and the manuscript edition	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
520814	15380028	MS	2	provided the tumor samples and patient information and were also involved in the manuscript edition	provided the tumor samples and patient information and were also involved in the manuscript edition	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Review & Editing	YES
520814	15380028	NC	2	were involved in the microarray production and the manuscript edition	were involved in the microarray production and the manuscript edition	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
520814	15380028	QC	2	carried out all experiments and participated in data analysis|drafted the manuscript	carried out all experiments and participated in data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
520814	15380028	QC	2	carried out all experiments and participated in data analysis|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
520814	15380028	SB	2	performed array cgh data analysis and statistical analysis|drafted the manuscript	performed array cgh data analysis and statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
520814	15380028	SB	2	performed array cgh data analysis and statistical analysis|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4423716	25973192	Alessandro Longheu	7	data collection, data analysis	data collection, data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4423716	25973192	Fabio Medas	7	data collection, data analysis	data collection, data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4423716	25973192	Francesco Podda	7	data collection, data analysis	data collection, data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4423716	25973192	Giuseppe Pisano	7	revising the article, data analysis	revising the article, data analysis	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4423716	25973192	Luca Gordini	7	study design, data interpretation, drafting the article	study design, data interpretation, drafting the article	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4423716	25973192	Maria Letizia Lai	7	drafting the article, histopathological analysis	drafting the article, histopathological analysis	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4423716	25973192	Pietro Giorgio Calo	7	study concept, revising the article, operation of the patient	study concept, revising the article, operation of the patient	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Review & Editing	YES
5498527	28729871	AK	2	were involved in dna isolation, genotyping, linkage maps construction and qtl analysis	were involved in dna isolation, genotyping, linkage maps construction and qtl analysis	Performed the experiments	Investigation	YES
5498527	28729871	AP	2	drafted the manuscript and all the authors reviewed and approved the final version of the manuscript	drafted the manuscript and all the authors reviewed and approved the final version of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5498527	28729871	BM	2	in planning and designing this study|were involved in developing mapping populations, designing field experiments, phenotyping and data analysis|were involved in dna isolation, genotyping, linkage maps construction and qtl analysis|drafted the manuscript and all the authors reviewed and approved the final version of the manuscript	in planning and designing this study	Conceived and designed the experiments	Methodology	YES
5498527	28729871	BM	2	in planning and designing this study|were involved in developing mapping populations, designing field experiments, phenotyping and data analysis|were involved in dna isolation, genotyping, linkage maps construction and qtl analysis|drafted the manuscript and all the authors reviewed and approved the final version of the manuscript	were involved in developing mapping populations, designing field experiments, phenotyping and data analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5498527	28729871	BM	2	in planning and designing this study|were involved in developing mapping populations, designing field experiments, phenotyping and data analysis|were involved in dna isolation, genotyping, linkage maps construction and qtl analysis|drafted the manuscript and all the authors reviewed and approved the final version of the manuscript	were involved in dna isolation, genotyping, linkage maps construction and qtl analysis	Performed the experiments	Investigation	YES
5498527	28729871	BM	2	in planning and designing this study|were involved in developing mapping populations, designing field experiments, phenotyping and data analysis|were involved in dna isolation, genotyping, linkage maps construction and qtl analysis|drafted the manuscript and all the authors reviewed and approved the final version of the manuscript	drafted the manuscript and all the authors reviewed and approved the final version of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5498527	28729871	KV	2	drafted the manuscript and all the authors reviewed and approved the final version of the manuscript	drafted the manuscript and all the authors reviewed and approved the final version of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5498527	28729871	MT	2	were involved in dna isolation, genotyping, linkage maps construction and qtl analysis|drafted the manuscript and all the authors reviewed and approved the final version of the manuscript	were involved in dna isolation, genotyping, linkage maps construction and qtl analysis	Performed the experiments	Investigation	YES
5498527	28729871	MT	2	were involved in dna isolation, genotyping, linkage maps construction and qtl analysis|drafted the manuscript and all the authors reviewed and approved the final version of the manuscript	drafted the manuscript and all the authors reviewed and approved the final version of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5498527	28729871	PG	2	coordinated this project|were involved in developing mapping populations, designing field experiments, phenotyping and data analysis|drafted the manuscript and all the authors reviewed and approved the final version of the manuscript	coordinated this project	-	Project administration	YES
5498527	28729871	PG	2	coordinated this project|were involved in developing mapping populations, designing field experiments, phenotyping and data analysis|drafted the manuscript and all the authors reviewed and approved the final version of the manuscript	were involved in developing mapping populations, designing field experiments, phenotyping and data analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5498527	28729871	PG	2	coordinated this project|were involved in developing mapping populations, designing field experiments, phenotyping and data analysis|drafted the manuscript and all the authors reviewed and approved the final version of the manuscript	drafted the manuscript and all the authors reviewed and approved the final version of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5498527	28729871	RV	2	were involved in dna isolation, genotyping, linkage maps construction and qtl analysis	were involved in dna isolation, genotyping, linkage maps construction and qtl analysis	Performed the experiments	Investigation	YES
5498527	28729871	SBS	2	were involved in developing mapping populations, designing field experiments, phenotyping and data analysis	were involved in developing mapping populations, designing field experiments, phenotyping and data analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5498527	28729871	SS	2	were involved in developing mapping populations, designing field experiments, phenotyping and data analysis|drafted the manuscript and all the authors reviewed and approved the final version of the manuscript	were involved in developing mapping populations, designing field experiments, phenotyping and data analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5498527	28729871	SS	2	were involved in developing mapping populations, designing field experiments, phenotyping and data analysis|drafted the manuscript and all the authors reviewed and approved the final version of the manuscript	drafted the manuscript and all the authors reviewed and approved the final version of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4403878	25894556	ACN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403878	25894556	ACN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4403878	25894556	ACN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403878	25894556	ACN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403878	25894556	ACN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403878	25894556	AS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4403878	25894556	AS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403878	25894556	MZ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4403878	25894556	MZ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4403878	25894556	MZ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403878	25894556	SJK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403878	25894556	SJK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4403878	25894556	SJK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4403878	25894556	SJK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4245448	25427633	HL	2	contributed to the design of the study, led statistical analyses and interpretation of results, and contributed to the drafting of the initial manuscript	contributed to the design of the study, led statistical analyses and interpretation of results, and contributed to the drafting of the initial manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4245448	25427633	JES	2	contributed significantly to the cleaning of data, statistical analyses and the drafting of the initial manuscript	contributed significantly to the cleaning of data, statistical analyses and the drafting of the initial manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
4245448	25427633	MLS	2	contributed significantly to carrying out study procedures, including coordination and supervision of data acquisition and interpretation of results, and to the drafting of the initial manuscript	contributed significantly to carrying out study procedures, including coordination and supervision of data acquisition and interpretation of results, and to the drafting of the initial manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Project administration|Resources|Supervision|Writing - Original Draft	YES
4245448	25427633	RCV	2	conceptualized and designed the study, oversaw statistical analyses and interpretation of results, and led the drafting of the manuscript	conceptualized and designed the study, oversaw statistical analyses and interpretation of results, and led the drafting of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Supervision|Writing - Original Draft	YES
4245448	25427633	SOA	2	contributed significantly to the initial conception and design of the study as well as to the critical review of the manuscript	contributed significantly to the initial conception and design of the study as well as to the critical review of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
4245448	25427633	TSI	2	contributed significantly to the initial conception and design of the study as well as to the critical review of the manuscript	contributed significantly to the initial conception and design of the study as well as to the critical review of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
4245448	25427633	WMN	2	conceptualized and designed the study, oversaw statistical analyses and interpretation of results, and led the drafting of the manuscript	conceptualized and designed the study, oversaw statistical analyses and interpretation of results, and led the drafting of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Supervision|Writing - Original Draft	YES
4245448	25427633	WT	2	contributed to the design of the study, led statistical analyses and interpretation of results, and contributed to the drafting of the initial manuscript	contributed to the design of the study, led statistical analyses and interpretation of results, and contributed to the drafting of the initial manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4430704	25984301	Cuneyt Kayaalp	1	Drafting of manuscript and/or critical revision|Approval of final version of manuscript	Drafting of manuscript and/or critical revision	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4430704	25984301	Cuneyt Kayaalp	1	Drafting of manuscript and/or critical revision|Approval of final version of manuscript	Approval of final version of manuscript	-	-	NO
4430704	25984301	Orhan Gozeneli	1	Drafting of manuscript and/or critical revision	Drafting of manuscript and/or critical revision	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4430704	25984301	Sertac Usta	1	Conception and design of study|Data analysis and/or interpretation	Conception and design of study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4430704	25984301	Sertac Usta	1	Conception and design of study|Data analysis and/or interpretation	Data analysis and/or interpretation	Analyzed the data	Formal analysis	YES
4454727	26090413	Danfeng Wei	2	contributed equally to this work	contributed equally to this work	-	-	NO
4454727	26090413	Qing Fan	2	contributed equally to this work	contributed equally to this work	-	-	NO
520820	15363096	AS	2	all contributed to the fish mapping aspects of the manuscript, including isolation of bac dna samples, generation of canine chromosome preparations, probe labeling and purification, fluorescence in situ hybridization, and microscopy	all contributed to the fish mapping aspects of the manuscript, including isolation of bac dna samples, generation of canine chromosome preparations, probe labeling and purification, fluorescence in situ hybridization, and microscopy	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Resources|Writing - Original Draft	YES
520820	15363096	CA	2	including analysis, quality control, supervision, and portions of manuscript production	including analysis, quality control, supervision, and portions of manuscript production	Performed the experiments	Supervision|Validation	YES
520820	15363096	CH	2	did the statistical analysis for the localization of the 4249 markers on the radiation hybrid map and the integration of the fish and rh maps	did the statistical analysis for the localization of the 4249 markers on the radiation hybrid map and the integration of the fish and rh maps	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
520820	15363096	EAO	2	including experimental design, quality control, supervision, and portions of manuscript production	including experimental design, quality control, supervision, and portions of manuscript production	Conceived and designed the experiments|Performed the experiments	Methodology|Supervision|Validation	YES
520820	15363096	FG	2	including analysis, quality control, supervision, and portions of manuscript production	including analysis, quality control, supervision, and portions of manuscript production	Performed the experiments	Supervision|Validation	YES
520820	15363096	MB	2	all contributed to the fish mapping aspects of the manuscript, including isolation of bac dna samples, generation of canine chromosome preparations, probe labeling and purification, fluorescence in situ hybridization, and microscopy|performed all the cytogenetic analysis to generate detailed probe ordering|also wrote and edited relevant sections of the manuscript	all contributed to the fish mapping aspects of the manuscript, including isolation of bac dna samples, generation of canine chromosome preparations, probe labeling and purification, fluorescence in situ hybridization, and microscopy	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Resources|Writing - Original Draft	YES
520820	15363096	MB	2	all contributed to the fish mapping aspects of the manuscript, including isolation of bac dna samples, generation of canine chromosome preparations, probe labeling and purification, fluorescence in situ hybridization, and microscopy|performed all the cytogenetic analysis to generate detailed probe ordering|also wrote and edited relevant sections of the manuscript	performed all the cytogenetic analysis to generate detailed probe ordering	Performed the experiments	Investigation	YES
520820	15363096	MB	2	all contributed to the fish mapping aspects of the manuscript, including isolation of bac dna samples, generation of canine chromosome preparations, probe labeling and purification, fluorescence in situ hybridization, and microscopy|performed all the cytogenetic analysis to generate detailed probe ordering|also wrote and edited relevant sections of the manuscript	also wrote and edited relevant sections of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
520820	15363096	RG	2	computed the marker sequences using blast software against the human sequence to identify orthologoussequences and synteny conservation|also drew some of the chromosomes for figures 1	computed the marker sequences using blast software against the human sequence to identify orthologoussequences and synteny conservation	Performed the experiments|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Software	YES
520820	15363096	RG	2	computed the marker sequences using blast software against the human sequence to identify orthologoussequences and synteny conservation|also drew some of the chromosomes for figures 1	also drew some of the chromosomes for figures 1	-	Visualization	YES
520820	15363096	RH	2	all contributed to the fish mapping aspects of the manuscript, including isolation of bac dna samples, generation of canine chromosome preparations, probe labeling and purification, fluorescence in situ hybridization, and microscopy|fish data, and prepared the drawing of figure 2 for both the manuscript and web sites	all contributed to the fish mapping aspects of the manuscript, including isolation of bac dna samples, generation of canine chromosome preparations, probe labeling and purification, fluorescence in situ hybridization, and microscopy	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Resources|Writing - Original Draft	YES
520820	15363096	RH	2	all contributed to the fish mapping aspects of the manuscript, including isolation of bac dna samples, generation of canine chromosome preparations, probe labeling and purification, fluorescence in situ hybridization, and microscopy|fish data, and prepared the drawing of figure 2 for both the manuscript and web sites	fish data, and prepared the drawing of figure 2 for both the manuscript and web sites	Contributed reagents/materials/analysis tools|Wrote the paper	Software|Visualization|Writing - Original Draft	YES
520820	15363096	RT	2	all contributed to the fish mapping aspects of the manuscript, including isolation of bac dna samples, generation of canine chromosome preparations, probe labeling and purification, fluorescence in situ hybridization, and microscopy	all contributed to the fish mapping aspects of the manuscript, including isolation of bac dna samples, generation of canine chromosome preparations, probe labeling and purification, fluorescence in situ hybridization, and microscopy	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Resources|Writing - Original Draft	YES
520820	15363096	TDL	2	also drafted portions of the methods section of the manuscript	also drafted portions of the methods section of the manuscript	Performed the experiments|Wrote the paper	Writing - Original Draft	YES
4430705	25984299	All	2	listed authors were involved in the article concept, development of article principles, critical review of the final article and approval of the final draft	listed authors were involved in the article concept, development of article principles, critical review of the final article and approval of the final draft	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
4252165	25466882	MAW	2	all contributed to the preparation of the manuscript	all contributed to the preparation of the manuscript	Wrote the paper	Writing - Original Draft	YES
4252165	25466882	MB	2	all contributed to the preparation of the manuscript	all contributed to the preparation of the manuscript	Wrote the paper	Writing - Original Draft	YES
4252165	25466882	PSS	2	all contributed to the preparation of the manuscript	all contributed to the preparation of the manuscript	Wrote the paper	Writing - Original Draft	YES
4252165	25466882	SK	2	all contributed to the preparation of the manuscript	all contributed to the preparation of the manuscript	Wrote the paper	Writing - Original Draft	YES
5498554	28729877	CC	2	performed the data analysis	performed the data analysis	Analyzed the data	Formal analysis	YES
5498554	28729877	HM	2	developed the association-mapping panel|performed the data analysis|revised the manuscript	developed the association-mapping panel	-	-	NO
5498554	28729877	HM	2	developed the association-mapping panel|performed the data analysis|revised the manuscript	performed the data analysis	Analyzed the data	Formal analysis	YES
5498554	28729877	HM	2	developed the association-mapping panel|performed the data analysis|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5498554	28729877	HZ	2	designed and supervised the study	designed and supervised the study	Conceived and designed the experiments	Methodology|Supervision	YES
5498554	28729877	YL	2	developed the association-mapping panel	developed the association-mapping panel	-	-	NO
5498554	28729877	YZ	2	designed and supervised the study	designed and supervised the study	Conceived and designed the experiments	Methodology|Supervision	YES
4403879	25894968	AP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403879	25894968	AP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4403879	25894968	AP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403879	25894968	DM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4403879	25894968	DM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403879	25894968	EVS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403879	25894968	EVS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403879	25894968	NMZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403879	25894968	NMZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4403879	25894968	NMZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403879	25894968	TR	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4403879	25894968	TR	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5209821	28052756	BL	2	carried out the bioinformatic analysis	carried out the bioinformatic analysis	Performed the experiments	Formal analysis|Investigation	YES
5209821	28052756	EC	2	conceived the study|performed the rna extraction, libraries preparation and sequencing|carried out pathway analysis|wrote the manuscript and generated the figures	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5209821	28052756	EC	2	conceived the study|performed the rna extraction, libraries preparation and sequencing|carried out pathway analysis|wrote the manuscript and generated the figures	performed the rna extraction, libraries preparation and sequencing	Performed the experiments	Investigation	YES
5209821	28052756	EC	2	conceived the study|performed the rna extraction, libraries preparation and sequencing|carried out pathway analysis|wrote the manuscript and generated the figures	carried out pathway analysis	Performed the experiments	Investigation	YES
5209821	28052756	EC	2	conceived the study|performed the rna extraction, libraries preparation and sequencing|carried out pathway analysis|wrote the manuscript and generated the figures	wrote the manuscript and generated the figures	Performed the experiments|Wrote the paper	Investigation|Visualization|Writing - Original Draft	YES
5209821	28052756	FP	2	conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5209821	28052756	FT	2	conceived the study|wrote the manuscript and generated the figures	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5209821	28052756	FT	2	conceived the study|wrote the manuscript and generated the figures	wrote the manuscript and generated the figures	Performed the experiments|Wrote the paper	Investigation|Visualization|Writing - Original Draft	YES
5209821	28052756	IF	2	carried out the bioinformatic analysis	carried out the bioinformatic analysis	Performed the experiments	Formal analysis|Investigation	YES
5209821	28052756	PC	2	performed the rna extraction, libraries preparation and sequencing	performed the rna extraction, libraries preparation and sequencing	Performed the experiments	Investigation	YES
4430706	25984300	JG	2	made large contributions to drafting this manuscript several times	made large contributions to drafting this manuscript several times	Wrote the paper	Writing - Original Draft	YES
4430706	25984300	KS	2	lead initial drafts of the entire manuscript	lead initial drafts of the entire manuscript	Wrote the paper	Writing - Original Draft	YES
4430706	25984300	MMG	2	led the case write up and literature review overall	led the case write up and literature review overall	Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4430706	25984300	MR	2	led the care of this patient, advised on themes to cover for drafting and edited the manuscript	led the care of this patient, advised on themes to cover for drafting and edited the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
4430706	25984300	OM	2	participated in the management of this patient, gained consent for use of images for publication of this case, advised on write up and edited the manuscript	participated in the management of this patient, gained consent for use of images for publication of this case, advised on write up and edited the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Investigation|Visualization|Writing - Original Draft|Writing - Review & Editing	YES
4256520	25477050	AM	2	contributed to the vision and design	contributed to the vision and design	Conceived and designed the experiments	-	YES
4256520	25477050	ES	2	contributed critical manuscript comments	contributed critical manuscript comments	-	-	NO
4256520	25477050	JM	2	contributed to the design and implementation	contributed to the design and implementation	Conceived and designed the experiments|Performed the experiments	Investigation	YES
4256520	25477050	KCP	2	contributed to the vision, design, implementation and critical manuscript comments	contributed to the vision, design, implementation and critical manuscript comments	Conceived and designed the experiments|Performed the experiments	Investigation	YES
4256520	25477050	KK	2	contributed to the implementation, data analysis and manuscript writing	contributed to the implementation, data analysis and manuscript writing	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft	YES
4256520	25477050	MJ	2	contributed to the design, implementation and critical comments on the final manuscript	contributed to the design, implementation and critical comments on the final manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4256520	25477050	RM	2	contributed to the vision and design	contributed to the vision and design	Conceived and designed the experiments	-	YES
4256520	25477050	SN	2	contributed to the vision and design	contributed to the vision and design	Conceived and designed the experiments	-	YES
4256520	25477050	TS	2	contributed to data analysis	contributed to data analysis	Analyzed the data	Formal analysis	YES
4256520	25477050	VM	2	contributed to the vision and design	contributed to the vision and design	Conceived and designed the experiments	-	YES
4403914	25894607	JHK	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403914	25894607	JWJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403914	25894607	JWJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403914	25894607	JWJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403914	25894607	JYC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403914	25894607	KWC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403914	25894607	SHB	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403914	25894607	SKY	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403914	25894607	SWL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403914	25894607	SWN	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403914	25894607	SWN	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4403914	25894607	YWK	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4434206	26005570	Ayman Alsebaey	7	Data collection and data analysis	Data collection and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4434206	26005570	Emad Hamdy Gad	7	Study design, data collection and writing	Study design, data collection and writing	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology	YES
4434206	26005570	Maha Lotfy	7	Data collection	Data collection	Performed the experiments	Investigation	YES
4434206	26005570	Mohamed Eltabbakh	7	Data collection	Data collection	Performed the experiments	Investigation	YES
4909611	27322480	AWS	2	contributed to the design and writing of the manuscript	contributed to the design and writing of the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
4909611	27322480	EM	2	assisted with the sensitivity analyses	assisted with the sensitivity analyses	Analyzed the data	Formal analysis	YES
4909611	27322480	HS	2	obtained temperature datasets, created the maps, developed program code and assisted with the calculations and drafting of the manuscript	obtained temperature datasets, created the maps, developed program code and assisted with the calculations and drafting of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Software|Writing - Original Draft	YES
4909611	27322480	JLH	2	carried out the modeling, generated the calculations, and drafted the manuscript	carried out the modeling, generated the calculations, and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4909611	27322480	JR	2	conceived the research, assisted with modeling and drafting of the manuscript	conceived the research, assisted with modeling and drafting of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
4909611	27322480	KE	2	provided scientific input into the manuscript and all authors discussed the results and contributed to the revision of the final manuscript	provided scientific input into the manuscript and all authors discussed the results and contributed to the revision of the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4909611	27322480	MQ	2	obtained temperature datasets, created the maps, developed program code and assisted with the calculations and drafting of the manuscript	obtained temperature datasets, created the maps, developed program code and assisted with the calculations and drafting of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Software|Writing - Original Draft	YES
5498556	28729874	CH	PLoS52	performed the experiments and bioinformatics|analyzed the data|wrote the manuscript	performed the experiments and bioinformatics	Performed the experiments	Formal analysis|Investigation	YES
5498556	28729874	CH	PLoS52	performed the experiments and bioinformatics|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5498556	28729874	CH	PLoS52	performed the experiments and bioinformatics|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5498556	28729874	HL	PLoS52	performed the experiments and bioinformatics	performed the experiments and bioinformatics	Performed the experiments	Formal analysis|Investigation	YES
5498556	28729874	JY	PLoS52	performed the experiments and bioinformatics	performed the experiments and bioinformatics	Performed the experiments	Formal analysis|Investigation	YES
5498556	28729874	LZ	PLoS52	performed the experiments and bioinformatics	performed the experiments and bioinformatics	Performed the experiments	Formal analysis|Investigation	YES
5498556	28729874	WH	PLoS52	conceived and designed the research	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5498556	28729874	XZ	PLoS52	conceived and designed the research|performed the experiments and bioinformatics|analyzed the data|wrote the manuscript	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5498556	28729874	XZ	PLoS52	conceived and designed the research|performed the experiments and bioinformatics|analyzed the data|wrote the manuscript	performed the experiments and bioinformatics	Performed the experiments	Formal analysis|Investigation	YES
5498556	28729874	XZ	PLoS52	conceived and designed the research|performed the experiments and bioinformatics|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5498556	28729874	XZ	PLoS52	conceived and designed the research|performed the experiments and bioinformatics|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5498556	28729874	ZH	PLoS52	performed the experiments and bioinformatics	performed the experiments and bioinformatics	Performed the experiments	Formal analysis|Investigation	YES
5209853	28049437	All authors	2	contributed to writing and revising the manuscript	contributed to writing and revising the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5209853	28049437	JT	2	were involved in study design, planning, analyses, and the interpretation of results	were involved in study design, planning, analyses, and the interpretation of results	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5209853	28049437	LN	2	developed the method, made the initial draft and implemented the software|were involved in study design, planning, analyses, and the interpretation of results	developed the method, made the initial draft and implemented the software	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Methodology|Software|Writing - Original Draft	YES
5209853	28049437	LN	2	developed the method, made the initial draft and implemented the software|were involved in study design, planning, analyses, and the interpretation of results	were involved in study design, planning, analyses, and the interpretation of results	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5209853	28049437	ZX	2	developed the method, made the initial draft and implemented the software|were involved in study design, planning, analyses, and the interpretation of results	developed the method, made the initial draft and implemented the software	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Methodology|Software|Writing - Original Draft	YES
5209853	28049437	ZX	2	developed the method, made the initial draft and implemented the software|were involved in study design, planning, analyses, and the interpretation of results	were involved in study design, planning, analyses, and the interpretation of results	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
4434207	26005566	Andrew Mavor	7	Study design and data collection assistance	Study design and data collection assistance	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4434207	26005566	Marina Yiasemidou	7	Study design, data collection, data analysis, writing up	Study design, data collection, data analysis, writing up	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology	YES
4434207	26005566	Patrick Kent	7	Study design, data analysis supervision and writing up	Study design, data analysis supervision and writing up	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Supervision	YES
4403916	25894395	HC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4403916	25894395	JDC	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4403916	25894395	NJA	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4403916	25894395	RZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4403916	25894395	TZZ	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403916	25894395	TZZ	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403916	25894395	WZG	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403916	25894395	YH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4403916	25894395	YKW	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4403916	25894395	YKW	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403916	25894395	YKW	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403916	25894395	ZYN	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4260459	25491351	BEN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the first draft of the manuscript|Contributed to the writing of the manuscript|Read and approved final manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4260459	25491351	BEN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the first draft of the manuscript|Contributed to the writing of the manuscript|Read and approved final manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4260459	25491351	BEN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the first draft of the manuscript|Contributed to the writing of the manuscript|Read and approved final manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4260459	25491351	BEN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the first draft of the manuscript|Contributed to the writing of the manuscript|Read and approved final manuscript	Wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
4260459	25491351	BEN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the first draft of the manuscript|Contributed to the writing of the manuscript|Read and approved final manuscript	Contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
4260459	25491351	BEN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the first draft of the manuscript|Contributed to the writing of the manuscript|Read and approved final manuscript	Read and approved final manuscript	Wrote the paper	Writing - Review & Editing	YES
4260459	25491351	CABB	PLoS5	Contributed to the writing of the manuscript|Read and approved final manuscript	Contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
4260459	25491351	CABB	PLoS5	Contributed to the writing of the manuscript|Read and approved final manuscript	Read and approved final manuscript	Wrote the paper	Writing - Review & Editing	YES
4260459	25491351	CK	PLoS5	Contributed to the writing of the manuscript|Read and approved final manuscript	Contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
4260459	25491351	CK	PLoS5	Contributed to the writing of the manuscript|Read and approved final manuscript	Read and approved final manuscript	Wrote the paper	Writing - Review & Editing	YES
4260459	25491351	DAMCvdV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the first draft of the manuscript|Contributed to the writing of the manuscript|Read and approved final manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4260459	25491351	DAMCvdV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the first draft of the manuscript|Contributed to the writing of the manuscript|Read and approved final manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4260459	25491351	DAMCvdV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the first draft of the manuscript|Contributed to the writing of the manuscript|Read and approved final manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4260459	25491351	DAMCvdV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the first draft of the manuscript|Contributed to the writing of the manuscript|Read and approved final manuscript	Wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
4260459	25491351	DAMCvdV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the first draft of the manuscript|Contributed to the writing of the manuscript|Read and approved final manuscript	Contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
4260459	25491351	DAMCvdV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the first draft of the manuscript|Contributed to the writing of the manuscript|Read and approved final manuscript	Read and approved final manuscript	Wrote the paper	Writing - Review & Editing	YES
4260459	25491351	KCES	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed to the writing of the manuscript|Read and approved final manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4260459	25491351	KCES	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed to the writing of the manuscript|Read and approved final manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4260459	25491351	KCES	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed to the writing of the manuscript|Read and approved final manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4260459	25491351	KCES	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed to the writing of the manuscript|Read and approved final manuscript	Contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
4260459	25491351	KCES	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed to the writing of the manuscript|Read and approved final manuscript	Read and approved final manuscript	Wrote the paper	Writing - Review & Editing	YES
4260459	25491351	MRJ	PLoS5	Contributed to the writing of the manuscript|Read and approved final manuscript	Contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
4260459	25491351	MRJ	PLoS5	Contributed to the writing of the manuscript|Read and approved final manuscript	Read and approved final manuscript	Wrote the paper	Writing - Review & Editing	YES
4260459	25491351	RB	PLoS5	Contributed to the writing of the manuscript|Read and approved final manuscript	Contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
4260459	25491351	RB	PLoS5	Contributed to the writing of the manuscript|Read and approved final manuscript	Read and approved final manuscript	Wrote the paper	Writing - Review & Editing	YES
4260459	25491351	RLH	PLoS5	Contributed to the writing of the manuscript|Read and approved final manuscript	Contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
4260459	25491351	RLH	PLoS5	Contributed to the writing of the manuscript|Read and approved final manuscript	Read and approved final manuscript	Wrote the paper	Writing - Review & Editing	YES
4260459	25491351	SB	PLoS5	Contributed to the writing of the manuscript|Read and approved final manuscript	Contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
4260459	25491351	SB	PLoS5	Contributed to the writing of the manuscript|Read and approved final manuscript	Read and approved final manuscript	Wrote the paper	Writing - Review & Editing	YES
4260459	25491351	TBH	PLoS5	Conceived and designed the experiments|Contributed to the writing of the manuscript|Read and approved final manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4260459	25491351	TBH	PLoS5	Conceived and designed the experiments|Contributed to the writing of the manuscript|Read and approved final manuscript	Contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
4260459	25491351	TBH	PLoS5	Conceived and designed the experiments|Contributed to the writing of the manuscript|Read and approved final manuscript	Read and approved final manuscript	Wrote the paper	Writing - Review & Editing	YES
4260459	25491351	TRW	PLoS5	Contributed to the writing of the manuscript|Read and approved final manuscript	Contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
4260459	25491351	TRW	PLoS5	Contributed to the writing of the manuscript|Read and approved final manuscript	Read and approved final manuscript	Wrote the paper	Writing - Review & Editing	YES
5209865	28049427	DO	2	conceived of, designed and coordinated the study, and edited the manuscript	conceived of, designed and coordinated the study, and edited the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Review & Editing	YES
5209865	28049427	EK	2	contributed to gene validation	contributed to gene validation	Performed the experiments	Validation	YES
5209865	28049427	IE	2	conceived of, designed and coordinated the study, and edited the manuscript	conceived of, designed and coordinated the study, and edited the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Review & Editing	YES
5209865	28049427	JMH	2	conceived of, designed and coordinated the study, and edited the manuscript	conceived of, designed and coordinated the study, and edited the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Review & Editing	YES
5209865	28049427	JV	2	participated in the study design, prepared the ijs and isolated the rna, analyzed the data, maintained the parasites and drafted the manuscript	participated in the study design, prepared the ijs and isolated the rna, analyzed the data, maintained the parasites and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5209865	28049427	MK	2	assisted with parasite husbandry	assisted with parasite husbandry	Performed the experiments	Investigation	YES
5209865	28049427	RR	2	participated in the study design	participated in the study design	Conceived and designed the experiments	Methodology	YES
4919474	27428418	AL	2	supervised and planned experiments|wrote the manuscript	supervised and planned experiments	Conceived and designed the experiments	Conceptualization|Supervision	YES
4919474	27428418	AL	2	supervised and planned experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4919474	27428418	BO	2	supervised and planned experiments|wrote the manuscript	supervised and planned experiments	Conceived and designed the experiments	Conceptualization|Supervision	YES
4919474	27428418	BO	2	supervised and planned experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4919474	27428418	CS	2	performed experiments, collected data, analyzed data and prepared figures|supervised and planned experiments|wrote the manuscript	performed experiments, collected data, analyzed data and prepared figures	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
4919474	27428418	CS	2	performed experiments, collected data, analyzed data and prepared figures|supervised and planned experiments|wrote the manuscript	supervised and planned experiments	Conceived and designed the experiments	Conceptualization|Supervision	YES
4919474	27428418	CS	2	performed experiments, collected data, analyzed data and prepared figures|supervised and planned experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4919474	27428418	DA	2	performed experiments, collected data, analyzed data and prepared figures|supervised and planned experiments|wrote the manuscript	performed experiments, collected data, analyzed data and prepared figures	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
4919474	27428418	DA	2	performed experiments, collected data, analyzed data and prepared figures|supervised and planned experiments|wrote the manuscript	supervised and planned experiments	Conceived and designed the experiments	Conceptualization|Supervision	YES
4919474	27428418	DA	2	performed experiments, collected data, analyzed data and prepared figures|supervised and planned experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4919474	27428418	HW	2	supervised and planned experiments|wrote the manuscript	supervised and planned experiments	Conceived and designed the experiments	Conceptualization|Supervision	YES
4919474	27428418	HW	2	supervised and planned experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4919474	27428418	JML	2	performed experiments, collected data, analyzed data and prepared figures	performed experiments, collected data, analyzed data and prepared figures	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
4919474	27428418	KG	2	performed experiments, collected data, analyzed data and prepared figures	performed experiments, collected data, analyzed data and prepared figures	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
4919474	27428418	KT	2	performed experiments, collected data, analyzed data and prepared figures|wrote the manuscript	performed experiments, collected data, analyzed data and prepared figures	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
4919474	27428418	KT	2	performed experiments, collected data, analyzed data and prepared figures|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4919474	27428418	LL	2	performed experiments, collected data, analyzed data and prepared figures	performed experiments, collected data, analyzed data and prepared figures	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
4919474	27428418	MB	2	performed experiments, collected data, analyzed data and prepared figures|supervised and planned experiments|wrote the manuscript	performed experiments, collected data, analyzed data and prepared figures	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
4919474	27428418	MB	2	performed experiments, collected data, analyzed data and prepared figures|supervised and planned experiments|wrote the manuscript	supervised and planned experiments	Conceived and designed the experiments	Conceptualization|Supervision	YES
4919474	27428418	MB	2	performed experiments, collected data, analyzed data and prepared figures|supervised and planned experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4919474	27428418	MBB	2	performed experiments, collected data, analyzed data and prepared figures|supervised and planned experiments|wrote the manuscript	performed experiments, collected data, analyzed data and prepared figures	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
4919474	27428418	MBB	2	performed experiments, collected data, analyzed data and prepared figures|supervised and planned experiments|wrote the manuscript	supervised and planned experiments	Conceived and designed the experiments	Conceptualization|Supervision	YES
4919474	27428418	MBB	2	performed experiments, collected data, analyzed data and prepared figures|supervised and planned experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4919474	27428418	MLN	2	performed experiments, collected data, analyzed data and prepared figures	performed experiments, collected data, analyzed data and prepared figures	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
4919474	27428418	MS	2	performed experiments, collected data, analyzed data and prepared figures|supervised and planned experiments|wrote the manuscript	performed experiments, collected data, analyzed data and prepared figures	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
4919474	27428418	MS	2	performed experiments, collected data, analyzed data and prepared figures|supervised and planned experiments|wrote the manuscript	supervised and planned experiments	Conceived and designed the experiments	Conceptualization|Supervision	YES
4919474	27428418	MS	2	performed experiments, collected data, analyzed data and prepared figures|supervised and planned experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4919474	27428418	SZ	2	supervised and planned experiments	supervised and planned experiments	Conceived and designed the experiments	Conceptualization|Supervision	YES
4919474	27428418	TOE	2	performed experiments, collected data, analyzed data and prepared figures|wrote the manuscript	performed experiments, collected data, analyzed data and prepared figures	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
4919474	27428418	TOE	2	performed experiments, collected data, analyzed data and prepared figures|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4919474	27428418	TS	2	performed experiments, collected data, analyzed data and prepared figures	performed experiments, collected data, analyzed data and prepared figures	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
4919474	27428418	US	2	performed experiments, collected data, analyzed data and prepared figures	performed experiments, collected data, analyzed data and prepared figures	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
4919474	27428418	YQZ	2	performed experiments, collected data, analyzed data and prepared figures	performed experiments, collected data, analyzed data and prepared figures	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
4919474	27428418	ZL	2	performed experiments, collected data, analyzed data and prepared figures|supervised and planned experiments|wrote the manuscript	performed experiments, collected data, analyzed data and prepared figures	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
4919474	27428418	ZL	2	performed experiments, collected data, analyzed data and prepared figures|supervised and planned experiments|wrote the manuscript	supervised and planned experiments	Conceived and designed the experiments	Conceptualization|Supervision	YES
4919474	27428418	ZL	2	performed experiments, collected data, analyzed data and prepared figures|supervised and planned experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6230926	30455960	HF	2	conceived, coordinated, designed, and analyzed the experiments as well as manuscript writing	conceived, coordinated, designed, and analyzed the experiments as well as manuscript writing	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Project administration|Writing - Original Draft	YES
6230926	30455960	HN	2	participated in the coordination of the experiments and draft manuscript writing	participated in the coordination of the experiments and draft manuscript writing	Performed the experiments|Wrote the paper	Investigation|Project administration|Writing - Original Draft	YES
6230926	30455960	JWR	2	participated in the coordination of the experiments and draft manuscript writing	participated in the coordination of the experiments and draft manuscript writing	Performed the experiments|Wrote the paper	Investigation|Project administration|Writing - Original Draft	YES
6230926	30455960	KF	2	carried out in silico computer analysis	carried out in silico computer analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6230926	30455960	KY	2	participated in the coordination of the experiments and draft manuscript writing	participated in the coordination of the experiments and draft manuscript writing	Performed the experiments|Wrote the paper	Investigation|Project administration|Writing - Original Draft	YES
6230926	30455960	MM	2	participated in the coordination of the experiments and draft manuscript writing	participated in the coordination of the experiments and draft manuscript writing	Performed the experiments|Wrote the paper	Investigation|Project administration|Writing - Original Draft	YES
6230926	30455960	NK	2	carried out luciferase assays and western blotting	carried out luciferase assays and western blotting	Performed the experiments	Investigation	YES
6230926	30455960	NS	2	carried out introducing mutations to the reporter vectors, luciferase assays, chip assay, western blotting, and cell imaging of hypoxia probe assays	carried out introducing mutations to the reporter vectors, luciferase assays, chip assay, western blotting, and cell imaging of hypoxia probe assays	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
6230926	30455960	NY	2	carried out luciferase assays and western blotting	carried out luciferase assays and western blotting	Performed the experiments	Investigation	YES
6230926	30455960	TM	2	participated in the coordination of the experiments and draft manuscript writing	participated in the coordination of the experiments and draft manuscript writing	Performed the experiments|Wrote the paper	Investigation|Project administration|Writing - Original Draft	YES
6230926	30455960	YA	2	carried out luciferase assays and western blotting	carried out luciferase assays and western blotting	Performed the experiments	Investigation	YES
4262765	25499123	GAU	2	conceived the study, participated in its design and statistical analysis, and drafted the manuscript	conceived the study, participated in its design and statistical analysis, and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
4262765	25499123	MM	2	participated in the acquisition of data	participated in the acquisition of data	Performed the experiments	Investigation	YES
4262765	25499123	PKN	2	participated in the acquisition of data	participated in the acquisition of data	Performed the experiments	Investigation	YES
4262765	25499123	RK	2	participated in the acquisition of data	participated in the acquisition of data	Performed the experiments	Investigation	YES
4403917	25894540	PT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403917	25894540	PT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4403917	25894540	PT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403917	25894540	PT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403917	25894540	SMPS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403917	25894540	SMPS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403917	25894540	SMPS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403917	25894540	SMPS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5500639	28736569	IS	4	The manuscript was written jointly by	The manuscript was written jointly by	Wrote the paper	Writing - Original Draft	YES
5500639	28736569	JU	4	The software and experiments were implemented by|The manuscript was written jointly by	The software and experiments were implemented by	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5500639	28736569	JU	4	The software and experiments were implemented by|The manuscript was written jointly by	The manuscript was written jointly by	Wrote the paper	Writing - Original Draft	YES
5209866	28049426	AD	2	conceived the research, interpreted the results and contributed to the preparation of the manuscript	conceived the research, interpreted the results and contributed to the preparation of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
5209866	28049426	FL	2	conceived the research, interpreted the results and contributed to the preparation of the manuscript	conceived the research, interpreted the results and contributed to the preparation of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
5209866	28049426	PG	2	conceived the research, interpreted the results and contributed to the preparation of the manuscript	conceived the research, interpreted the results and contributed to the preparation of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
5209866	28049426	QZ	2	performed the sample collection, library preparation, gene annotation and qpcr analyses, participated in the bioinformatics and statistical analyses and drafted the methods section|helped with the interpretation of the data directed toward the bioinformatics pipelines, designed and performed the statistical analyses and wrote the manuscript	performed the sample collection, library preparation, gene annotation and qpcr analyses, participated in the bioinformatics and statistical analyses and drafted the methods section	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Formal analysis|Investigation|Writing - Original Draft	YES
5209866	28049426	QZ	2	performed the sample collection, library preparation, gene annotation and qpcr analyses, participated in the bioinformatics and statistical analyses and drafted the methods section|helped with the interpretation of the data directed toward the bioinformatics pipelines, designed and performed the statistical analyses and wrote the manuscript	helped with the interpretation of the data directed toward the bioinformatics pipelines, designed and performed the statistical analyses and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Supervision|Writing - Original Draft	YES
5209866	28049426	SL	2	helped with the interpretation of the data directed toward the bioinformatics pipelines, designed and performed the statistical analyses and wrote the manuscript	helped with the interpretation of the data directed toward the bioinformatics pipelines, designed and performed the statistical analyses and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Supervision|Writing - Original Draft	YES
5209866	28049426	ZZ	2	helped with the interpretation of the data directed toward the bioinformatics pipelines, designed and performed the statistical analyses and wrote the manuscript	helped with the interpretation of the data directed toward the bioinformatics pipelines, designed and performed the statistical analyses and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Supervision|Writing - Original Draft	YES
4434209	26005567	Kiran Natarajan	7	Literature review. Dr.Sudhamaheswari - Literature review	Literature review. Dr.Sudhamaheswari - Literature review	-	Formal analysis	YES
4434209	26005567	Mohan Kameswaran	7	Study Concept, Manuscript review and interpretation of result	Study Concept, Manuscript review and interpretation of result	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Review & Editing	YES
4434209	26005567	Vijaya Krishnan	7	Data Collection, Preparation of Manuscript, Art work. Dr.SathiyaMurali - Preparation of Manuscript. Dr	Data Collection, Preparation of Manuscript, Art work. Dr.SathiyaMurali - Preparation of Manuscript. Dr	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4265114	25499456	CW	2	prepared the first draft of the paper|refined the draft and finalised the paper	prepared the first draft of the paper	Wrote the paper	Writing - Original Draft	YES
4265114	25499456	CW	2	prepared the first draft of the paper|refined the draft and finalised the paper	refined the draft and finalised the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4265114	25499456	JS	2	refined the draft and finalised the paper	refined the draft and finalised the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4919504	27428426	All authors	2	discussed the results and commented on the manuscript	discussed the results and commented on the manuscript	-	-	NO
4919504	27428426	BL	2	contributed to and supervised statistical analysis	contributed to and supervised statistical analysis	Analyzed the data	Formal analysis|Supervision	YES
4919504	27428426	MS	2	transfection and imaging experiments, analyzed microscopy data and designed and performed cell cycle experiments	transfection and imaging experiments, analyzed microscopy data and designed and performed cell cycle experiments	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology|Visualization	YES
4919504	27428426	SA	2	generated mutant constructs and performed wound-healing and flow cytometry experiments	generated mutant constructs and performed wound-healing and flow cytometry experiments	Performed the experiments	Investigation	YES
4436506	26005571	BK	2	were involved in the conception, design and interpretation|wrote the manuscript|collected data, reviewed relevant published reports and provided the images	were involved in the conception, design and interpretation	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
4436506	26005571	BK	2	were involved in the conception, design and interpretation|wrote the manuscript|collected data, reviewed relevant published reports and provided the images	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4436506	26005571	BK	2	were involved in the conception, design and interpretation|wrote the manuscript|collected data, reviewed relevant published reports and provided the images	collected data, reviewed relevant published reports and provided the images	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
4436506	26005571	BY	2	were involved in the conception, design and interpretation|wrote the manuscript	were involved in the conception, design and interpretation	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
4436506	26005571	BY	2	were involved in the conception, design and interpretation|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4436506	26005571	HM	2	were involved in the conception, design and interpretation	were involved in the conception, design and interpretation	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
4436506	26005571	SM	2	were involved in the conception, design and interpretation|wrote the manuscript|collected data, reviewed relevant published reports and provided the images	were involved in the conception, design and interpretation	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
4436506	26005571	SM	2	were involved in the conception, design and interpretation|wrote the manuscript|collected data, reviewed relevant published reports and provided the images	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4436506	26005571	SM	2	were involved in the conception, design and interpretation|wrote the manuscript|collected data, reviewed relevant published reports and provided the images	collected data, reviewed relevant published reports and provided the images	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
4436506	26005571	ST	2	wrote the manuscript|collected data, reviewed relevant published reports and provided the images	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4436506	26005571	ST	2	wrote the manuscript|collected data, reviewed relevant published reports and provided the images	collected data, reviewed relevant published reports and provided the images	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
4436506	26005571	TMD	2	were involved in the conception, design and interpretation|wrote the manuscript|collected data, reviewed relevant published reports and provided the images	were involved in the conception, design and interpretation	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
4436506	26005571	TMD	2	were involved in the conception, design and interpretation|wrote the manuscript|collected data, reviewed relevant published reports and provided the images	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4436506	26005571	TMD	2	were involved in the conception, design and interpretation|wrote the manuscript|collected data, reviewed relevant published reports and provided the images	collected data, reviewed relevant published reports and provided the images	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
4403918	25893438	AJC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403918	25893438	AJC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4403918	25893438	AJC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403918	25893438	AJC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403918	25893438	CL	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403918	25893438	CL	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403918	25893438	CR	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403918	25893438	CR	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403918	25893438	GH	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403918	25893438	GH	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403918	25893438	JAW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403918	25893438	JAW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4403918	25893438	JAW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403918	25893438	JAW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403918	25893438	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403918	25893438	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4403918	25893438	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403918	25893438	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403918	25893438	MvK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403918	25893438	MvK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403918	25893438	MvK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403918	25893438	OB	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403918	25893438	OB	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403918	25893438	SK	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403918	25893438	SK	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403918	25893438	SW	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403918	25893438	SW	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5500643	28736566	ADP	2	population development and phenotyping	population development and phenotyping	Performed the experiments	Investigation	YES
5500643	28736566	Ph.D.	2	genomics support	genomics support	Performed the experiments	Investigation	YES
5209871	28049436	JB	2	participated in the overall conceptual and experimental design of this study, analysis and interpretation of results, as well as in drafting the manuscript	participated in the overall conceptual and experimental design of this study, analysis and interpretation of results, as well as in drafting the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5209871	28049436	MJM	2	participated in its design and coordination and helped to draft the manuscript	participated in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Project administration|Writing - Original Draft	YES
4268491	25516092	AMF	2	performed the data analysis and interpretation|drafted the manuscript	performed the data analysis and interpretation	Analyzed the data	Formal analysis	YES
4268491	25516092	AMF	2	performed the data analysis and interpretation|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4268491	25516092	CCM	2	designed the survey and coordinated data collection|revised the manuscript	designed the survey and coordinated data collection	Conceived and designed the experiments|Performed the experiments	Investigation|Project administration	YES
4268491	25516092	CCM	2	designed the survey and coordinated data collection|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4268491	25516092	CWW	2	performed the data analysis and interpretation|drafted the manuscript	performed the data analysis and interpretation	Analyzed the data	Formal analysis	YES
4268491	25516092	CWW	2	performed the data analysis and interpretation|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4268491	25516092	DAC	2	designed the survey and coordinated data collection|revised the manuscript	designed the survey and coordinated data collection	Conceived and designed the experiments|Performed the experiments	Investigation|Project administration	YES
4268491	25516092	DAC	2	designed the survey and coordinated data collection|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4268491	25516092	DKE	2	designed the survey and coordinated data collection|revised the manuscript	designed the survey and coordinated data collection	Conceived and designed the experiments|Performed the experiments	Investigation|Project administration	YES
4268491	25516092	DKE	2	designed the survey and coordinated data collection|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4268491	25516092	DN	2	designed the survey and coordinated data collection|performed the data analysis and interpretation|drafted the manuscript	designed the survey and coordinated data collection	Conceived and designed the experiments|Performed the experiments	Investigation|Project administration	YES
4268491	25516092	DN	2	designed the survey and coordinated data collection|performed the data analysis and interpretation|drafted the manuscript	performed the data analysis and interpretation	Analyzed the data	Formal analysis	YES
4268491	25516092	DN	2	designed the survey and coordinated data collection|performed the data analysis and interpretation|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4268491	25516092	JH	2	designed the survey and coordinated data collection	designed the survey and coordinated data collection	Conceived and designed the experiments|Performed the experiments	Investigation|Project administration	YES
4268491	25516092	KW	2	designed the survey and coordinated data collection|revised the manuscript	designed the survey and coordinated data collection	Conceived and designed the experiments|Performed the experiments	Investigation|Project administration	YES
4268491	25516092	KW	2	designed the survey and coordinated data collection|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4268491	25516092	MB	2	performed the data analysis and interpretation|drafted the manuscript	performed the data analysis and interpretation	Analyzed the data	Formal analysis	YES
4268491	25516092	MB	2	performed the data analysis and interpretation|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4268491	25516092	ME	2	designed the survey and coordinated data collection	designed the survey and coordinated data collection	Conceived and designed the experiments|Performed the experiments	Investigation|Project administration	YES
4268491	25516092	MLL	2	performed the data analysis and interpretation|drafted the manuscript	performed the data analysis and interpretation	Analyzed the data	Formal analysis	YES
4268491	25516092	MLL	2	performed the data analysis and interpretation|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4268491	25516092	RDM	2	designed the survey and coordinated data collection|revised the manuscript	designed the survey and coordinated data collection	Conceived and designed the experiments|Performed the experiments	Investigation|Project administration	YES
4268491	25516092	RDM	2	designed the survey and coordinated data collection|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4268491	25516092	SND	2	designed the survey and coordinated data collection|performed the data analysis and interpretation|drafted the manuscript	designed the survey and coordinated data collection	Conceived and designed the experiments|Performed the experiments	Investigation|Project administration	YES
4268491	25516092	SND	2	designed the survey and coordinated data collection|performed the data analysis and interpretation|drafted the manuscript	performed the data analysis and interpretation	Analyzed the data	Formal analysis	YES
4268491	25516092	SND	2	designed the survey and coordinated data collection|performed the data analysis and interpretation|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4919537	27428442	A.L.	2	performed statistical analysis, prepared figures and tables	performed statistical analysis, prepared figures and tables	Analyzed the data	Formal analysis|Visualization	YES
4919537	27428442	All authors	2	provided critical comments on the manuscript content and approved the final version of the manuscript	provided critical comments on the manuscript content and approved the final version of the manuscript	-	-	NO
4919537	27428442	C.D.	2	provided input into the drosophila memory experiments	provided input into the drosophila memory experiments	-	-	NO
4919537	27428442	C.R.	2	performed the drosophila memory experiments and prepared the figures|helped with designing and executing the child neurodevelopmental testing	performed the drosophila memory experiments and prepared the figures	Performed the experiments	Investigation|Visualization	YES
4919537	27428442	C.R.	2	performed the drosophila memory experiments and prepared the figures|helped with designing and executing the child neurodevelopmental testing	helped with designing and executing the child neurodevelopmental testing	Conceived and designed the experiments|Performed the experiments	Investigation	YES
4919537	27428442	F.V.B.	2	conceptualized, analyzed, prepared figures for the drosophila experiments and co-wrote the manuscript	conceptualized, analyzed, prepared figures for the drosophila experiments and co-wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Visualization|Writing - Original Draft	YES
4919537	27428442	J.P.	2	helped with designing and executing the child neurodevelopmental testing	helped with designing and executing the child neurodevelopmental testing	Conceived and designed the experiments|Performed the experiments	Investigation	YES
4919537	27428442	L.L.	2	provided input into the drosophila memory experiments	provided input into the drosophila memory experiments	-	-	NO
4919537	27428442	L.S.	2	helped with manuscript development	helped with manuscript development	-	-	NO
4919537	27428442	N.W.	2	provided input into the drosophila memory experiments	provided input into the drosophila memory experiments	-	-	NO
4919537	27428442	P.M.	2	conceived the study, obtained funding for the study, wrote the first draft of the manuscript and drafted the final version of the manuscript	conceived the study, obtained funding for the study, wrote the first draft of the manuscript and drafted the final version of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Funding acquisition|Writing - Original Draft	YES
4919537	27428442	R.T.A.	2	provided input into the drosophila memory experiments	provided input into the drosophila memory experiments	-	-	NO
4919537	27428442	S.E.T.	2	helped obtain funding, advised on the child study design, and participated in data collection	helped obtain funding, advised on the child study design, and participated in data collection	Conceived and designed the experiments|Performed the experiments	Funding acquisition|Investigation|Methodology	YES
4919537	27428442	S.L.	2	performed the drosophila memory experiments and prepared the figures	performed the drosophila memory experiments and prepared the figures	Performed the experiments	Investigation|Visualization	YES
4403919	25894610	JHB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403919	25894610	JHB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4403919	25894610	JHB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403919	25894610	JHB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403919	25894610	JHB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403919	25894610	JMK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403919	25894610	JMK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4403919	25894610	JMK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403919	25894610	JMK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403919	25894610	JMK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4442693	26042185	Eiji Sunami	7	data collection	data collection	Performed the experiments	Investigation	YES
4442693	26042185	Hiroaki Nozawa	7	data collection	data collection	Performed the experiments	Investigation	YES
4442693	26042185	Hironori Yamaguchi	7	data collection	data collection	Performed the experiments	Investigation	YES
4442693	26042185	Joji Kitayama	7	data collection	data collection	Performed the experiments	Investigation	YES
4442693	26042185	Junichiro Tanaka	7	study design, data collections, data analysis, writing	study design, data collections, data analysis, writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology	YES
4442693	26042185	Kazushige Kawai	7	data collection	data collection	Performed the experiments	Investigation	YES
4442693	26042185	Keisuke Hata	7	data collection, data analysis, writing	data collection, data analysis, writing	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation	YES
4442693	26042185	Shinsuke Kazama	7	data collection	data collection	Performed the experiments	Investigation	YES
4442693	26042185	Soichiro Ishihara	7	data collection, writing	data collection, writing	Performed the experiments|Wrote the paper	Investigation	YES
4442693	26042185	Takeshi Nishikawa	7	data collection	data collection	Performed the experiments	Investigation	YES
4442693	26042185	Tomomichi Kiyomatsu	7	data collection	data collection	Performed the experiments	Investigation	YES
4442693	26042185	Toshiaki Tanaka	7	data collection	data collection	Performed the experiments	Investigation	YES
4442693	26042185	Toshiaki Watanabe	7	writing	writing	Wrote the paper	-	YES
5209891	28049423	AF	2	helped design the study and write the manuscript	helped design the study and write the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5209891	28049423	ATU	2	analysed all data and drafted manuscript	analysed all data and drafted manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5209891	28049423	IC	2	analysed all data and drafted manuscript	analysed all data and drafted manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5209891	28049423	NG	2	performed laboratory experiments	performed laboratory experiments	Performed the experiments	Investigation	YES
5209891	28049423	SD	2	designed the study and received funding	designed the study and received funding	Conceived and designed the experiments	Funding acquisition|Methodology	YES
4458275	26090432	Bruno do Valle Pinheiro	2	were responsible for the design and conduct of the project, interpretation of results, and composition of all sections of the paper	were responsible for the design and conduct of the project, interpretation of results, and composition of all sections of the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
4458275	26090432	Daniel Rodrigues Teixeira	2	carried out data collection for all the patients and analysis of the data	carried out data collection for all the patients and analysis of the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4458275	26090432	Edimar Pedrosa Gomes	2	were responsible for the design and conduct of the project, interpretation of results, and composition of all sections of the paper|drafted the paper and performed the literature reviews|carried out data collection for all the patients and analysis of the data|did the statistical analysis	were responsible for the design and conduct of the project, interpretation of results, and composition of all sections of the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
4458275	26090432	Edimar Pedrosa Gomes	2	were responsible for the design and conduct of the project, interpretation of results, and composition of all sections of the paper|drafted the paper and performed the literature reviews|carried out data collection for all the patients and analysis of the data|did the statistical analysis	drafted the paper and performed the literature reviews	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4458275	26090432	Edimar Pedrosa Gomes	2	were responsible for the design and conduct of the project, interpretation of results, and composition of all sections of the paper|drafted the paper and performed the literature reviews|carried out data collection for all the patients and analysis of the data|did the statistical analysis	carried out data collection for all the patients and analysis of the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4458275	26090432	Edimar Pedrosa Gomes	2	were responsible for the design and conduct of the project, interpretation of results, and composition of all sections of the paper|drafted the paper and performed the literature reviews|carried out data collection for all the patients and analysis of the data|did the statistical analysis	did the statistical analysis	Analyzed the data	Formal analysis	YES
4458275	26090432	Erich Vidal Carvalho	2	carried out data collection for all the patients and analysis of the data|did the statistical analysis	carried out data collection for all the patients and analysis of the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4458275	26090432	Erich Vidal Carvalho	2	carried out data collection for all the patients and analysis of the data|did the statistical analysis	did the statistical analysis	Analyzed the data	Formal analysis	YES
4458275	26090432	Gilberto Francisco Ferreira	2	carried out data collection for all the patients and analysis of the data	carried out data collection for all the patients and analysis of the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4458275	26090432	Helady Sanders Pinheiro	2	helped out with data analysis and provided intellectual content of critical importance to the work described	helped out with data analysis and provided intellectual content of critical importance to the work described	Analyzed the data	Formal analysis	YES
4458275	26090432	Julio Cesar Abreu	2	helped out with data analysis and provided intellectual content of critical importance to the work described	helped out with data analysis and provided intellectual content of critical importance to the work described	Analyzed the data	Formal analysis	YES
4458275	26090432	Julio Maria Fonseca	2	helped out with data analysis and provided intellectual content of critical importance to the work described	helped out with data analysis and provided intellectual content of critical importance to the work described	Analyzed the data	Formal analysis	YES
4458275	26090432	Lais Fernanda Caldi	2	carried out data collection for all the patients and analysis of the data	carried out data collection for all the patients and analysis of the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4458275	26090432	Maycon de Moura Reboredo	2	were responsible for the design and conduct of the project, interpretation of results, and composition of all sections of the paper	were responsible for the design and conduct of the project, interpretation of results, and composition of all sections of the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
4458275	26090432	Ornellas Carvalho	2	carried out data collection for all the patients and analysis of the data	carried out data collection for all the patients and analysis of the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4458275	26090432	Rogerio Baumgratz	2	helped out with data analysis and provided intellectual content of critical importance to the work described	helped out with data analysis and provided intellectual content of critical importance to the work described	Analyzed the data	Formal analysis	YES
4272405	25527333	AA	2	participated in its final writing and editing	participated in its final writing and editing	Wrote the paper	Writing - Review & Editing	YES
4272405	25527333	AAMD	2	conceived and designed the study protocol|performed the virological analyses|wrote the initial manuscript	conceived and designed the study protocol	Conceived and designed the experiments	Conceptualization|Methodology	YES
4272405	25527333	AAMD	2	conceived and designed the study protocol|performed the virological analyses|wrote the initial manuscript	performed the virological analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4272405	25527333	AAMD	2	conceived and designed the study protocol|performed the virological analyses|wrote the initial manuscript	wrote the initial manuscript	Wrote the paper	Writing - Original Draft	YES
4272405	25527333	CTK	2	conceived and designed the study protocol|participated in its final writing and editing	conceived and designed the study protocol	Conceived and designed the experiments	Conceptualization|Methodology	YES
4272405	25527333	CTK	2	conceived and designed the study protocol|participated in its final writing and editing	participated in its final writing and editing	Wrote the paper	Writing - Review & Editing	YES
4272405	25527333	FB	2	contributed materials and to data collection	contributed materials and to data collection	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4272405	25527333	HDN	2	conceived and designed the study protocol	conceived and designed the study protocol	Conceived and designed the experiments	Conceptualization|Methodology	YES
4272405	25527333	IB	2	performed the virological analyses	performed the virological analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4272405	25527333	MC	2	contributed materials and to data collection	contributed materials and to data collection	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4272405	25527333	NB	2	performed the virological analyses	performed the virological analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5500646	28736570	NX	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
5500646	28736570	NX	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5500646	28736570	QC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
5500646	28736570	QC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5500646	28736570	QW	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5500646	28736570	XY	PLoS5	Designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Designed the experiments	Conceived and designed the experiments	Methodology	YES
5500646	28736570	XY	PLoS5	Designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
5500646	28736570	XY	PLoS5	Designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5500646	28736570	XY	PLoS5	Designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5500646	28736570	XY	PLoS5	Designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5500646	28736570	YoY	PLoS5	Designed the experiments	Designed the experiments	Conceived and designed the experiments	Methodology	YES
5500646	28736570	YuY	PLoS5	Designed the experiments|Analyzed the data	Designed the experiments	Conceived and designed the experiments	Methodology	YES
5500646	28736570	YuY	PLoS5	Designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4919562	27428430	A.H.Q.N.	1	Acquisition of data	Acquisition of data	Performed the experiments	Investigation	YES
4919562	27428430	A.J.	1	Acquisition of data	Acquisition of data	Performed the experiments	Investigation	YES
4919562	27428430	A.W.	1	Acquisition of data	Acquisition of data	Performed the experiments	Investigation	YES
4919562	27428430	All authors	1	Critical revision of the manuscript for important intellectual content	Critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4919562	27428430	C.K.O.	1	Acquisition of data	Acquisition of data	Performed the experiments	Investigation	YES
4919562	27428430	C.L.	1	Acquisition of data|Analysis and interpretation of data|Statistical analysis	Acquisition of data	Performed the experiments	Investigation	YES
4919562	27428430	C.L.	1	Acquisition of data|Analysis and interpretation of data|Statistical analysis	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
4919562	27428430	C.L.	1	Acquisition of data|Analysis and interpretation of data|Statistical analysis	Statistical analysis	Analyzed the data	Formal analysis	YES
4919562	27428430	C.P.	1	Study concept and design|Acquisition of data|Analysis and interpretation of data|Drafting of the manuscript|Technical/material support	Study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4919562	27428430	C.P.	1	Study concept and design|Acquisition of data|Analysis and interpretation of data|Drafting of the manuscript|Technical/material support	Acquisition of data	Performed the experiments	Investigation	YES
4919562	27428430	C.P.	1	Study concept and design|Acquisition of data|Analysis and interpretation of data|Drafting of the manuscript|Technical/material support	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
4919562	27428430	C.P.	1	Study concept and design|Acquisition of data|Analysis and interpretation of data|Drafting of the manuscript|Technical/material support	Drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
4919562	27428430	C.P.	1	Study concept and design|Acquisition of data|Analysis and interpretation of data|Drafting of the manuscript|Technical/material support	Technical/material support	Performed the experiments	Investigation	YES
4919562	27428430	C.W.	1	Technical/material support	Technical/material support	Performed the experiments	Investigation	YES
4919562	27428430	D.B.	1	Acquisition of data	Acquisition of data	Performed the experiments	Investigation	YES
4919562	27428430	D.G.D.	1	Obtained funding|Technical/material support	Obtained funding	-	Funding acquisition	YES
4919562	27428430	D.G.D.	1	Obtained funding|Technical/material support	Technical/material support	Performed the experiments	Investigation	YES
4919562	27428430	D.M.Y.T.	1	Technical/material support	Technical/material support	Performed the experiments	Investigation	YES
4919562	27428430	I.P.	1	Technical/material support	Technical/material support	Performed the experiments	Investigation	YES
4919562	27428430	J.N.	1	Study concept and design|Acquisition of data|Analysis and interpretation of data|Drafting of the manuscript|Obtained funding	Study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4919562	27428430	J.N.	1	Study concept and design|Acquisition of data|Analysis and interpretation of data|Drafting of the manuscript|Obtained funding	Acquisition of data	Performed the experiments	Investigation	YES
4919562	27428430	J.N.	1	Study concept and design|Acquisition of data|Analysis and interpretation of data|Drafting of the manuscript|Obtained funding	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
4919562	27428430	J.N.	1	Study concept and design|Acquisition of data|Analysis and interpretation of data|Drafting of the manuscript|Obtained funding	Drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
4919562	27428430	J.N.	1	Study concept and design|Acquisition of data|Analysis and interpretation of data|Drafting of the manuscript|Obtained funding	Obtained funding	-	Funding acquisition	YES
4919562	27428430	K.G.Y.	1	Acquisition of data	Acquisition of data	Performed the experiments	Investigation	YES
4919562	27428430	K.H.L.	1	Technical/material support	Technical/material support	Performed the experiments	Investigation	YES
4919562	27428430	K.R.C.	1	Study concept and design|Acquisition of data|Analysis and interpretation of data|Drafting of the manuscript|Statistical analysis	Study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4919562	27428430	K.R.C.	1	Study concept and design|Acquisition of data|Analysis and interpretation of data|Drafting of the manuscript|Statistical analysis	Acquisition of data	Performed the experiments	Investigation	YES
4919562	27428430	K.R.C.	1	Study concept and design|Acquisition of data|Analysis and interpretation of data|Drafting of the manuscript|Statistical analysis	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
4919562	27428430	K.R.C.	1	Study concept and design|Acquisition of data|Analysis and interpretation of data|Drafting of the manuscript|Statistical analysis	Drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
4919562	27428430	K.R.C.	1	Study concept and design|Acquisition of data|Analysis and interpretation of data|Drafting of the manuscript|Statistical analysis	Statistical analysis	Analyzed the data	Formal analysis	YES
4919562	27428430	N.K.	1	Technical/material support	Technical/material support	Performed the experiments	Investigation	YES
4919562	27428430	N.N.	1	Study concept and design|Acquisition of data|Analysis and interpretation of data|Drafting of the manuscript|Obtained funding	Study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4919562	27428430	N.N.	1	Study concept and design|Acquisition of data|Analysis and interpretation of data|Drafting of the manuscript|Obtained funding	Acquisition of data	Performed the experiments	Investigation	YES
4919562	27428430	N.N.	1	Study concept and design|Acquisition of data|Analysis and interpretation of data|Drafting of the manuscript|Obtained funding	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
4919562	27428430	N.N.	1	Study concept and design|Acquisition of data|Analysis and interpretation of data|Drafting of the manuscript|Obtained funding	Drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
4919562	27428430	N.N.	1	Study concept and design|Acquisition of data|Analysis and interpretation of data|Drafting of the manuscript|Obtained funding	Obtained funding	-	Funding acquisition	YES
4919562	27428430	P.T.	1	Acquisition of data|Obtained funding	Acquisition of data	Performed the experiments	Investigation	YES
4919562	27428430	P.T.	1	Acquisition of data|Obtained funding	Obtained funding	-	Funding acquisition	YES
4919562	27428430	P.Y.	1	Technical/material support	Technical/material support	Performed the experiments	Investigation	YES
4919562	27428430	R.S.	1	Technical/material support	Technical/material support	Performed the experiments	Investigation	YES
4919562	27428430	S.D.	1	Technical/material support	Technical/material support	Performed the experiments	Investigation	YES
4919562	27428430	S.H.C.	1	Study concept and design|Acquisition of data|Analysis and interpretation of data|Drafting of the manuscript	Study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4919562	27428430	S.H.C.	1	Study concept and design|Acquisition of data|Analysis and interpretation of data|Drafting of the manuscript	Acquisition of data	Performed the experiments	Investigation	YES
4919562	27428430	S.H.C.	1	Study concept and design|Acquisition of data|Analysis and interpretation of data|Drafting of the manuscript	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
4919562	27428430	S.H.C.	1	Study concept and design|Acquisition of data|Analysis and interpretation of data|Drafting of the manuscript	Drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
4919562	27428430	S.P.C.	1	Acquisition of data	Acquisition of data	Performed the experiments	Investigation	YES
4919562	27428430	S.W.	1	Technical/material support	Technical/material support	Performed the experiments	Investigation	YES
4919562	27428430	T.B.T.	1	Obtained funding	Obtained funding	-	Funding acquisition	YES
4919562	27428430	V.B.	1	Technical/material support	Technical/material support	Performed the experiments	Investigation	YES
4919562	27428430	Z.F.	1	Acquisition of data	Acquisition of data	Performed the experiments	Investigation	YES
4403920	25893245	AZ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4403920	25893245	AZ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403920	25893245	AZ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403920	25893245	CC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403920	25893245	CC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403920	25893245	CC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403920	25893245	FB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403920	25893245	FB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403920	25893245	FB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403920	25893245	FB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403920	25893245	GGL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403920	25893245	GGL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403920	25893245	GGL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403920	25893245	GGL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403920	25893245	GM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403920	25893245	GM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403920	25893245	GM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403920	25893245	MGP	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4403920	25893245	MGP	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403920	25893245	SAN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403920	25893245	SAN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403920	25893245	SAN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403920	25893245	SAN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403920	25893245	SN	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403920	25893245	SN	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403920	25893245	SN	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403920	25893245	SS	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4403920	25893245	SS	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403920	25893245	VP	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4403920	25893245	VP	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403920	25893245	VS	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4403920	25893245	VS	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4446552	26029364	FAA	7	writing	writing	Wrote the paper	-	YES
4446552	26029364	MS	7	writing	writing	Wrote the paper	-	YES
4446552	26029364	SAA	7	writing	writing	Wrote the paper	-	YES
4403922	25894744	AV	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403922	25894744	AV	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403922	25894744	AV	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403922	25894744	CL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403922	25894744	LLV	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4403922	25894744	LLV	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4403922	25894744	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403922	25894744	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4403922	25894744	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403922	25894744	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403922	25894744	PL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403922	25894744	XC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403922	25894744	XMY	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403922	25894744	XMY	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403922	25894744	XMY	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403922	25894744	YF	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4403922	25894744	YG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4403922	25894744	ZY	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4273177	25529498	AD	2	were responsible for the conception and design of this study|supervised the undertook the primary data analyses under|wrote the first draft of the manuscript	were responsible for the conception and design of this study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4273177	25529498	AD	2	were responsible for the conception and design of this study|supervised the undertook the primary data analyses under|wrote the first draft of the manuscript	supervised the undertook the primary data analyses under	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Supervision	YES
4273177	25529498	AD	2	were responsible for the conception and design of this study|supervised the undertook the primary data analyses under|wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
4273177	25529498	All authors	2	have made significant contributions to this study|have seen and approved the final version of the manuscript	have made significant contributions to this study	-	-	NO
4273177	25529498	All authors	2	have made significant contributions to this study|have seen and approved the final version of the manuscript	have seen and approved the final version of the manuscript	-	-	NO
4273177	25529498	CP	2	were responsible for the conception and design of this study|were responsible for the questionnaire development and adaptation to the context of indonesia|were responsible for selecting the sampling method, and for collecting and assembling the data in indonesia|undertook the primary data analyses under|wrote the first draft of the manuscript	were responsible for the conception and design of this study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4273177	25529498	CP	2	were responsible for the conception and design of this study|were responsible for the questionnaire development and adaptation to the context of indonesia|were responsible for selecting the sampling method, and for collecting and assembling the data in indonesia|undertook the primary data analyses under|wrote the first draft of the manuscript	were responsible for the questionnaire development and adaptation to the context of indonesia	-	-	NO
4273177	25529498	CP	2	were responsible for the conception and design of this study|were responsible for the questionnaire development and adaptation to the context of indonesia|were responsible for selecting the sampling method, and for collecting and assembling the data in indonesia|undertook the primary data analyses under|wrote the first draft of the manuscript	were responsible for selecting the sampling method, and for collecting and assembling the data in indonesia	Performed the experiments	Investigation	YES
4273177	25529498	CP	2	were responsible for the conception and design of this study|were responsible for the questionnaire development and adaptation to the context of indonesia|were responsible for selecting the sampling method, and for collecting and assembling the data in indonesia|undertook the primary data analyses under|wrote the first draft of the manuscript	undertook the primary data analyses under	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4273177	25529498	CP	2	were responsible for the conception and design of this study|were responsible for the questionnaire development and adaptation to the context of indonesia|were responsible for selecting the sampling method, and for collecting and assembling the data in indonesia|undertook the primary data analyses under|wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
4273177	25529498	GH	2	were responsible for the questionnaire development and adaptation to the context of indonesia	were responsible for the questionnaire development and adaptation to the context of indonesia	-	-	NO
4273177	25529498	PR	2	were responsible for selecting the sampling method, and for collecting and assembling the data in indonesia	were responsible for selecting the sampling method, and for collecting and assembling the data in indonesia	Performed the experiments	Investigation	YES
4273177	25529498	all other authors	2	contributed to further drafts and approved the final manuscript	contributed to further drafts and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4454785	26052436	Chang Chun-Ming	1	Acquisition of data	Acquisition of data	Performed the experiments	Investigation	YES
4454785	26052436	Chen Jian-Han	1	Design|Acquisition of data|Analysis and interpretation|Manuscript drafted by	Design	Conceived and designed the experiments	-	YES
4454785	26052436	Chen Jian-Han	1	Design|Acquisition of data|Analysis and interpretation|Manuscript drafted by	Acquisition of data	Performed the experiments	Investigation	YES
4454785	26052436	Chen Jian-Han	1	Design|Acquisition of data|Analysis and interpretation|Manuscript drafted by	Analysis and interpretation	Analyzed the data	Formal analysis	YES
4454785	26052436	Chen Jian-Han	1	Design|Acquisition of data|Analysis and interpretation|Manuscript drafted by	Manuscript drafted by	Wrote the paper	Writing - Original Draft	YES
4454785	26052436	Hsu Ta-Wen	1	Acquisition of data	Acquisition of data	Performed the experiments	Investigation	YES
4454785	26052436	Lee Cheng-Hung	1	Design|Acquisition of data|Analysis and interpretation|Revision	Design	Conceived and designed the experiments	-	YES
4454785	26052436	Lee Cheng-Hung	1	Design|Acquisition of data|Analysis and interpretation|Revision	Acquisition of data	Performed the experiments	Investigation	YES
4454785	26052436	Lee Cheng-Hung	1	Design|Acquisition of data|Analysis and interpretation|Revision	Analysis and interpretation	Analyzed the data	Formal analysis	YES
4454785	26052436	Lee Cheng-Hung	1	Design|Acquisition of data|Analysis and interpretation|Revision	Revision	Wrote the paper	Writing - Review & Editing	YES
4454785	26052436	Wei Chang-Kuo	1	Acquisition of data	Acquisition of data	Performed the experiments	Investigation	YES
4454785	26052436	Yin Wen-Yao	1	Design|Revision	Design	Conceived and designed the experiments	-	YES
4454785	26052436	Yin Wen-Yao	1	Design|Revision	Revision	Wrote the paper	Writing - Review & Editing	YES
6277375	30534379	CR	1	Participated in research design|Conducted experiments|Performed data analysis|Wrote or contributed to the writing of the manuscript	Participated in research design	Conceived and designed the experiments	-	YES
6277375	30534379	CR	1	Participated in research design|Conducted experiments|Performed data analysis|Wrote or contributed to the writing of the manuscript	Conducted experiments	Performed the experiments	Investigation	YES
6277375	30534379	CR	1	Participated in research design|Conducted experiments|Performed data analysis|Wrote or contributed to the writing of the manuscript	Performed data analysis	Analyzed the data	Formal analysis	YES
6277375	30534379	CR	1	Participated in research design|Conducted experiments|Performed data analysis|Wrote or contributed to the writing of the manuscript	Wrote or contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
6277375	30534379	DP	1	Contributed new reagents or analytic tools	Contributed new reagents or analytic tools	Contributed reagents/materials/analysis tools	Resources	YES
6277375	30534379	EM	1	Contributed new reagents or analytic tools	Contributed new reagents or analytic tools	Contributed reagents/materials/analysis tools	Resources	YES
6277375	30534379	FF	1	Conducted experiments|Performed data analysis	Conducted experiments	Performed the experiments	Investigation	YES
6277375	30534379	FF	1	Conducted experiments|Performed data analysis	Performed data analysis	Analyzed the data	Formal analysis	YES
6277375	30534379	GC	1	Participated in research design|Wrote or contributed to the writing of the manuscript	Participated in research design	Conceived and designed the experiments	-	YES
6277375	30534379	GC	1	Participated in research design|Wrote or contributed to the writing of the manuscript	Wrote or contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
6277375	30534379	RG	1	Contributed new reagents or analytic tools|Wrote or contributed to the writing of the manuscript	Contributed new reagents or analytic tools	Contributed reagents/materials/analysis tools	Resources	YES
6277375	30534379	RG	1	Contributed new reagents or analytic tools|Wrote or contributed to the writing of the manuscript	Wrote or contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
6277375	30534379	RKR	1	Contributed new reagents or analytic tools|Wrote or contributed to the writing of the manuscript	Contributed new reagents or analytic tools	Contributed reagents/materials/analysis tools	Resources	YES
6277375	30534379	RKR	1	Contributed new reagents or analytic tools|Wrote or contributed to the writing of the manuscript	Wrote or contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
4403923	25894570	AK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4403923	25894570	HY	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4403923	25894570	KN	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403923	25894570	MM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403923	25894570	MM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403923	25894570	MM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403923	25894570	NH	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4403923	25894570	NH	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4403923	25894570	NO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403923	25894570	NO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4403923	25894570	NO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403923	25894570	NO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403923	25894570	RK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4403923	25894570	TH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4403923	25894570	TM	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403923	25894570	TM	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5209911	28049418	AR	2	helped with the wrote the manuscript with	helped with the wrote the manuscript with	Wrote the paper	Writing - Original Draft	YES
5209911	28049418	BA	2	helped with the wrote the manuscript with	helped with the wrote the manuscript with	Wrote the paper	Writing - Original Draft	YES
5209911	28049418	BR	2	wrote the manuscript with	wrote the manuscript with	Wrote the paper	Writing - Original Draft	YES
5209911	28049418	BRM	2	conducted the bioinformatics analyses	conducted the bioinformatics analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5209911	28049418	PR	2	helped with the wrote the manuscript with	helped with the wrote the manuscript with	Wrote the paper	Writing - Original Draft	YES
5209911	28049418	RG	2	provided useful comments about the chimpipe method and the biological results|helped with the wrote the manuscript with	provided useful comments about the chimpipe method and the biological results	Performed the experiments	-	YES
5209911	28049418	RG	2	provided useful comments about the chimpipe method and the biological results|helped with the wrote the manuscript with	helped with the wrote the manuscript with	Wrote the paper	Writing - Original Draft	YES
5209911	28049418	SD	2	conducted the bioinformatics analyses|supervised the project|wrote the manuscript with	conducted the bioinformatics analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5209911	28049418	SD	2	conducted the bioinformatics analyses|supervised the project|wrote the manuscript with	supervised the project	-	Supervision	YES
5209911	28049418	SD	2	conducted the bioinformatics analyses|supervised the project|wrote the manuscript with	wrote the manuscript with	Wrote the paper	Writing - Original Draft	YES
5500647	28736567	AC	2	contributed to the generation of experimental work	contributed to the generation of experimental work	Performed the experiments	Investigation	YES
5500647	28736567	AR	2	generated the experimental work, analyzed the results, and contributed to manuscript confection	generated the experimental work, analyzed the results, and contributed to manuscript confection	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5500647	28736567	JS	2	designed the experiments, supervised them, analyzed the results, and confectioned the manuscript	designed the experiments, supervised them, analyzed the results, and confectioned the manuscript	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology|Supervision	YES
4283027	25556374	JKBM	2	made substantial contributions to the conception and design of the study, revised the paper for important intellectual content, and gave the final approval for submission of the manuscript	made substantial contributions to the conception and design of the study, revised the paper for important intellectual content, and gave the final approval for submission of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
4283027	25556374	ME	2	conceived and led the design of the study protocol, supervised data collection and led the analysis of data|wrote the first draft of the paper and revised the paper for substantial intellectual content	conceived and led the design of the study protocol, supervised data collection and led the analysis of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation|Methodology|Supervision	YES
4283027	25556374	ME	2	conceived and led the design of the study protocol, supervised data collection and led the analysis of data|wrote the first draft of the paper and revised the paper for substantial intellectual content	wrote the first draft of the paper and revised the paper for substantial intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4283027	25556374	NMT	2	made substantial contributions to the conception and design of the study, revised the paper for important intellectual content, and gave the final approval for submission of the manuscript	made substantial contributions to the conception and design of the study, revised the paper for important intellectual content, and gave the final approval for submission of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
4283027	25556374	RB	2	made substantial contributions to the acquisition and interpretation of data, revised the paper for important intellectual content and gave final approval for submission of the manuscript	made substantial contributions to the acquisition and interpretation of data, revised the paper for important intellectual content and gave final approval for submission of the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Review & Editing	YES
4283027	25556374	RKW	2	made substantial contributions to the conception and design of the study, revised the paper for important intellectual content, and gave the final approval for submission of the manuscript	made substantial contributions to the conception and design of the study, revised the paper for important intellectual content, and gave the final approval for submission of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
4287633	25571857	AD	2	assisted in data collection, data management and reviewed the manuscript	assisted in data collection, data management and reviewed the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Investigation|Writing - Review & Editing	YES
4287633	25571857	EA	2	reviewed the study protocol, provided guidance on the conduct of the study and critically reviewed the manuscript for important intellectual content	reviewed the study protocol, provided guidance on the conduct of the study and critically reviewed the manuscript for important intellectual content	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Supervision|Writing - Review & Editing	YES
4287633	25571857	EC	2	critically reviewed the manuscript for important intellectual content	critically reviewed the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4287633	25571857	GP	2	assisted in statistical analysis, interpretation and manuscript writing	assisted in statistical analysis, interpretation and manuscript writing	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4287633	25571857	KK	2	assisted in data collection, data management and reviewed the manuscript	assisted in data collection, data management and reviewed the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Investigation|Writing - Review & Editing	YES
4287633	25571857	MH	2	critically reviewed the manuscript for important intellectual content	critically reviewed the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4287633	25571857	MHK	2	conceived and designed the study, were responsible for study coordination and data management, helped analyze the data, interpreted findings and wrote the manuscript	conceived and designed the study, were responsible for study coordination and data management, helped analyze the data, interpreted findings and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Data curation|Formal analysis|Methodology|Project administration|Writing - Original Draft	YES
4287633	25571857	PNK	2	reviewed the study protocol, provided guidance on the conduct of the study and critically reviewed the manuscript for important intellectual content	reviewed the study protocol, provided guidance on the conduct of the study and critically reviewed the manuscript for important intellectual content	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Supervision|Writing - Review & Editing	YES
4287633	25571857	RS	2	assisted in data collection, data management and reviewed the manuscript	assisted in data collection, data management and reviewed the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Investigation|Writing - Review & Editing	YES
4287633	25571857	SA	2	conceived and designed the study, were responsible for study coordination and data management, helped analyze the data, interpreted findings and wrote the manuscript	conceived and designed the study, were responsible for study coordination and data management, helped analyze the data, interpreted findings and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Data curation|Formal analysis|Methodology|Project administration|Writing - Original Draft	YES
4287633	25571857	TPG	2	critically reviewed the manuscript for important intellectual content	critically reviewed the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5209917	28049435	CX	2	developed the project idea|developed the barcode-aware variant caller and performed statistical analyses in the paper|evaluated the variant caller performance|performed various analyses and wrote the paper	developed the project idea	Conceived and designed the experiments	Conceptualization	YES
5209917	28049435	CX	2	developed the project idea|developed the barcode-aware variant caller and performed statistical analyses in the paper|evaluated the variant caller performance|performed various analyses and wrote the paper	developed the barcode-aware variant caller and performed statistical analyses in the paper	Analyzed the data|Wrote the paper	Formal analysis|Software|Writing - Original Draft	YES
5209917	28049435	CX	2	developed the project idea|developed the barcode-aware variant caller and performed statistical analyses in the paper|evaluated the variant caller performance|performed various analyses and wrote the paper	evaluated the variant caller performance	Performed the experiments	Investigation	YES
5209917	28049435	CX	2	developed the project idea|developed the barcode-aware variant caller and performed statistical analyses in the paper|evaluated the variant caller performance|performed various analyses and wrote the paper	performed various analyses and wrote the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5209917	28049435	JD	2	developed the project idea|selected the target list of variants|designed all the primers and wrote the read processing pipeline|performed various analyses and wrote the paper	developed the project idea	Conceived and designed the experiments	Conceptualization	YES
5209917	28049435	JD	2	developed the project idea|selected the target list of variants|designed all the primers and wrote the read processing pipeline|performed various analyses and wrote the paper	selected the target list of variants	-	-	NO
5209917	28049435	JD	2	developed the project idea|selected the target list of variants|designed all the primers and wrote the read processing pipeline|performed various analyses and wrote the paper	designed all the primers and wrote the read processing pipeline	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
5209917	28049435	JD	2	developed the project idea|selected the target list of variants|designed all the primers and wrote the read processing pipeline|performed various analyses and wrote the paper	performed various analyses and wrote the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5209917	28049435	MNR	2	selected the target list of variants|evaluated the variant caller performance|performed various analyses and wrote the paper	selected the target list of variants	-	-	NO
5209917	28049435	MNR	2	selected the target list of variants|evaluated the variant caller performance|performed various analyses and wrote the paper	evaluated the variant caller performance	Performed the experiments	Investigation	YES
5209917	28049435	MNR	2	selected the target list of variants|evaluated the variant caller performance|performed various analyses and wrote the paper	performed various analyses and wrote the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5209917	28049435	YW	2	developed the project idea|performed various analyses and wrote the paper	developed the project idea	Conceived and designed the experiments	Conceptualization	YES
5209917	28049435	YW	2	developed the project idea|performed various analyses and wrote the paper	performed various analyses and wrote the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5209917	28049435	ZW	2	carried out the enrichment and sequencing experiments	carried out the enrichment and sequencing experiments	Performed the experiments	Investigation	YES
4403924	25894562	AK	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403924	25894562	AK	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403924	25894562	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403924	25894562	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4403924	25894562	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4403924	25894562	AWA	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403924	25894562	EMS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403924	25894562	EMS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4403924	25894562	EMS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403924	25894562	EMS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403924	25894562	EMS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403924	25894562	HAA	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403924	25894562	HYT	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403924	25894562	MB	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403924	25894562	MB	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4403924	25894562	ML	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403924	25894562	RA	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4403924	25894562	SP	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403924	25894562	VDR	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403924	25894562	VL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403924	25894562	VL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4403924	25894562	VL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4403924	25894562	VV	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403924	25894562	YYK	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5500663	28736568	FZ	2	helped to perform the physiological experiments and promoter analysis	helped to perform the physiological experiments and promoter analysis	Performed the experiments	Investigation	YES
5500663	28736568	GH	2	conceived the study, designed experiments and wrote the manuscript	conceived the study, designed experiments and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
5500663	28736568	GY	2	conceived the study, designed experiments and wrote the manuscript	conceived the study, designed experiments and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
5500663	28736568	JF	2	helped to perform the physiological experiments and promoter analysis	helped to perform the physiological experiments and promoter analysis	Performed the experiments	Investigation	YES
5500663	28736568	QL	2	performed all the experiments, analyzed the data and wrote the manuscript	performed all the experiments, analyzed the data and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5500663	28736568	QW	2	generated the transgenic tobacco plants and helped to perform other experiments	generated the transgenic tobacco plants and helped to perform other experiments	Performed the experiments	Investigation	YES
5500663	28736568	RW	2	helped to perform the physiological experiments and promoter analysis	helped to perform the physiological experiments and promoter analysis	Performed the experiments	Investigation	YES
5500663	28736568	SZ	2	helped to perform the physiological experiments and promoter analysis	helped to perform the physiological experiments and promoter analysis	Performed the experiments	Investigation	YES
5500663	28736568	YH	2	helped to perform the physiological experiments and promoter analysis	helped to perform the physiological experiments and promoter analysis	Performed the experiments	Investigation	YES
5500663	28736568	YZ	2	helped to perform the physiological experiments and promoter analysis	helped to perform the physiological experiments and promoter analysis	Performed the experiments	Investigation	YES
6293176	30564368	H.J.A.	2	wrote or contributed to the writing of the manuscript	wrote or contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
6293176	30564368	I.T.	2	conducted experiments	conducted experiments	Performed the experiments	Investigation	YES
6293176	30564368	T.F.	2	participated in research design|conducted experiments|wrote or contributed to the writing of the manuscript	participated in research design	Conceived and designed the experiments	-	YES
6293176	30564368	T.F.	2	participated in research design|conducted experiments|wrote or contributed to the writing of the manuscript	conducted experiments	Performed the experiments	Investigation	YES
6293176	30564368	T.F.	2	participated in research design|conducted experiments|wrote or contributed to the writing of the manuscript	wrote or contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
6293176	30564368	T.T.	2	conducted experiments	conducted experiments	Performed the experiments	Investigation	YES
6293176	30564368	Y.H.	2	participated in research design|wrote or contributed to the writing of the manuscript	participated in research design	Conceived and designed the experiments	-	YES
6293176	30564368	Y.H.	2	participated in research design|wrote or contributed to the writing of the manuscript	wrote or contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
4455911	26052435	Harith M. Alkhateeb	7	surgery for Cases 1 and 2, writing of original text, design of fig. 1 , communication with editorial team	surgery for Cases 1 and 2, writing of original text, design of fig. 1 , communication with editorial team	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
4455911	26052435	Thaer J. Aljanabi	7	surgery for Case 3, surgical photography, preparation of references	surgery for Case 3, surgical photography, preparation of references	Performed the experiments	Investigation|Visualization	YES
4403925	25894517	DK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403925	25894517	DK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4403925	25894517	DK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403925	25894517	DK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403925	25894517	DK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403925	25894517	IM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403925	25894517	IM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4403925	25894517	IM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403925	25894517	IM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403925	25894517	IM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403925	25894517	JJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403925	25894517	JJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403925	25894517	JJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403925	25894517	JJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403925	25894517	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403925	25894517	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4403925	25894517	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403925	25894517	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403925	25894517	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4289674	25579801	CL	2	drafted and revised the manuscript	drafted and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4289674	25579801	JA	2	critically reviewed and revised the manuscript	critically reviewed and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4289674	25579801	JSC	2	critically reviewed and revised the manuscript	critically reviewed and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4289674	25579801	MW	2	drafted and revised the manuscript	drafted and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4486463	26150908	Abdulkadir Unsal	7	Revising article critically	Revising article critically	Wrote the paper	Writing - Review & Editing	YES
4486463	26150908	Canan Besleyici	7	The acquisition of data	The acquisition of data	Performed the experiments	Investigation	YES
4486463	26150908	Ebru Oran	7	Study design and writing article	Study design and writing article	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4486463	26150908	Hakan Seyit	7	The acquisition of data	The acquisition of data	Performed the experiments	Investigation	YES
4486463	26150908	Halil Alis	7	Final approval of the version to be submitted	Final approval of the version to be submitted	-	-	NO
3330760	22523526	All authors	2	were involved in the research reported and drafted and approved the final manuscript	were involved in the research reported and drafted and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5209944	28049421	All authors	2	reviewed and approved the manuscript	reviewed and approved the manuscript	Wrote the paper	Writing - Review & Editing	YES
5209944	28049421	CS	2	discussed the interpretation of the data	discussed the interpretation of the data	Analyzed the data	Formal analysis	YES
5209944	28049421	CTR	2	conceived the project and designed the components|discussed the interpretation of the data|contributed rna seq data|prepared the manuscript	conceived the project and designed the components	Conceived and designed the experiments	Conceptualization|Methodology	YES
5209944	28049421	CTR	2	conceived the project and designed the components|discussed the interpretation of the data|contributed rna seq data|prepared the manuscript	discussed the interpretation of the data	Analyzed the data	Formal analysis	YES
5209944	28049421	CTR	2	conceived the project and designed the components|discussed the interpretation of the data|contributed rna seq data|prepared the manuscript	contributed rna seq data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5209944	28049421	CTR	2	conceived the project and designed the components|discussed the interpretation of the data|contributed rna seq data|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5209944	28049421	GAD	2	discussed the interpretation of the data	discussed the interpretation of the data	Analyzed the data	Formal analysis	YES
5209944	28049421	KS	2	contributed rna seq data	contributed rna seq data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5209944	28049421	S.B.	2	carried out all bioinformatics and statistical analyses	carried out all bioinformatics and statistical analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5209944	28049421	SB	2	conceived the project and designed the components|discussed the interpretation of the data|prepared the manuscript	conceived the project and designed the components	Conceived and designed the experiments	Conceptualization|Methodology	YES
5209944	28049421	SB	2	conceived the project and designed the components|discussed the interpretation of the data|prepared the manuscript	discussed the interpretation of the data	Analyzed the data	Formal analysis	YES
5209944	28049421	SB	2	conceived the project and designed the components|discussed the interpretation of the data|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5209944	28049421	SJB	2	conceived the project and designed the components|discussed the interpretation of the data	conceived the project and designed the components	Conceived and designed the experiments	Conceptualization|Methodology	YES
5209944	28049421	SJB	2	conceived the project and designed the components|discussed the interpretation of the data	discussed the interpretation of the data	Analyzed the data	Formal analysis	YES
5209944	28049421	TB-M	2	conceived the project and designed the components|discussed the interpretation of the data|prepared the manuscript	conceived the project and designed the components	Conceived and designed the experiments	Conceptualization|Methodology	YES
5209944	28049421	TB-M	2	conceived the project and designed the components|discussed the interpretation of the data|prepared the manuscript	discussed the interpretation of the data	Analyzed the data	Formal analysis	YES
5209944	28049421	TB-M	2	conceived the project and designed the components|discussed the interpretation of the data|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5209944	28049421	VC	2	discussed the interpretation of the data	discussed the interpretation of the data	Analyzed the data	Formal analysis	YES
4972485	27333048	AG	7	Participant recruitment, acquisition of data, revising the manuscript and final approval of the article 13. Piscoya A: Participant recruitment, acquisition of data, revising the manuscript and final approval of the article 14. Fedorov E: Participant recruitment, acquisition of data, revising the manuscript and final approval of the article 15. Bialek	Participant recruitment, acquisition of data, revising the manuscript and final approval of the article 13. Piscoya A: Participant recruitment, acquisition of data, revising the manuscript and final approval of the article 14. Fedorov E: Participant recruitment, acquisition of data, revising the manuscript and final approval of the article 15. Bialek	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4972485	27333048	AP	7	Participant recruitment, acquisition of data, revising the manuscript and final approval of the article 16. Mitrakov A: Participant recruitment, acquisition of data, revising the manuscript and final approval of the article 17. Caro L: Participant recruitment, acquisition of data, revising the manuscript and final approval of the article 18. Gonen C: Participant recruitment, acquisition of data, revising the manuscript and final approval of the article 19. Dolwani S: Participant recruitment, acquisition of data, revising the manuscript and final approval of the article 20. Farca A: Participant recruitment, acquisition of data, revising the manuscript and final approval of the article 21. Cuaresma	Participant recruitment, acquisition of data, revising the manuscript and final approval of the article 16. Mitrakov A: Participant recruitment, acquisition of data, revising the manuscript and final approval of the article 17. Caro L: Participant recruitment, acquisition of data, revising the manuscript and final approval of the article 18. Gonen C: Participant recruitment, acquisition of data, revising the manuscript and final approval of the article 19. Dolwani S: Participant recruitment, acquisition of data, revising the manuscript and final approval of the article 20. Farca A: Participant recruitment, acquisition of data, revising the manuscript and final approval of the article 21. Cuaresma	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4972485	27333048	CA	7	Participant recruitment, acquisition of data, revising the manuscript and final approval of the article 37	Participant recruitment, acquisition of data, revising the manuscript and final approval of the article 37	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4972485	27333048	CM	7	Participant recruitment, acquisition of data, revising the manuscript and final approval of the article 39. Singh R: Participant recruitment, acquisition of data, revising the manuscript and final approval of the article 40. Banerjee R: Participant recruitment, acquisition of data, revising the manuscript and final approval of the article 41. Anagnostopoulos	Participant recruitment, acquisition of data, revising the manuscript and final approval of the article 39. Singh R: Participant recruitment, acquisition of data, revising the manuscript and final approval of the article 40. Banerjee R: Participant recruitment, acquisition of data, revising the manuscript and final approval of the article 41. Anagnostopoulos	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4972485	27333048	Cardona Castro Fiho	7	Participant recruitment, acquisition of data, revising the manuscript and final approval of the article 7. Pittayanon R: Participant recruitment, acquisition of data, revising the manuscript and final approval of the article 8. Olano C: Participant recruitment, acquisition of data, revising the manuscript and final approval of the article 9. Yao F: Participant recruitment, acquisition of data, revising the manuscript and final approval of the article 10. Parra-Blanco A: Participant recruitment, acquisition of data, revising the manuscript and final approval of the article 11. Ho	Participant recruitment, acquisition of data, revising the manuscript and final approval of the article 7. Pittayanon R: Participant recruitment, acquisition of data, revising the manuscript and final approval of the article 8. Olano C: Participant recruitment, acquisition of data, revising the manuscript and final approval of the article 9. Yao F: Participant recruitment, acquisition of data, revising the manuscript and final approval of the article 10. Parra-Blanco A: Participant recruitment, acquisition of data, revising the manuscript and final approval of the article 11. Ho	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4972485	27333048	DG	7	Participant recruitment, acquisition of data, revising the manuscript and final approval of the article 29. Piskorz	Participant recruitment, acquisition of data, revising the manuscript and final approval of the article 29. Piskorz	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4972485	27333048	DM	7	Participant recruitment, acquisition of data, revising the manuscript and final approval of the article 36. Waldbaum	Participant recruitment, acquisition of data, revising the manuscript and final approval of the article 36. Waldbaum	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4972485	27333048	EC	7	Participant recruitment, acquisition of data, revising the manuscript and final approval of the article 7. Pittayanon R: Participant recruitment, acquisition of data, revising the manuscript and final approval of the article 8. Olano C: Participant recruitment, acquisition of data, revising the manuscript and final approval of the article 9. Yao F: Participant recruitment, acquisition of data, revising the manuscript and final approval of the article 10. Parra-Blanco A: Participant recruitment, acquisition of data, revising the manuscript and final approval of the article 11. Ho	Participant recruitment, acquisition of data, revising the manuscript and final approval of the article 7. Pittayanon R: Participant recruitment, acquisition of data, revising the manuscript and final approval of the article 8. Olano C: Participant recruitment, acquisition of data, revising the manuscript and final approval of the article 9. Yao F: Participant recruitment, acquisition of data, revising the manuscript and final approval of the article 10. Parra-Blanco A: Participant recruitment, acquisition of data, revising the manuscript and final approval of the article 11. Ho	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4972485	27333048	GH	7	Participant recruitment, acquisition of data, revising the manuscript and final approval of the article 34. Ang	Participant recruitment, acquisition of data, revising the manuscript and final approval of the article 34. Ang	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4972485	27333048	GK	7	Participant recruitment, acquisition of data, revising the manuscript and final approval of the article 42. Takahashi Y: Engineering, acquisition of data, revising the manuscript and final approval of the article	Participant recruitment, acquisition of data, revising the manuscript and final approval of the article 42. Takahashi Y: Engineering, acquisition of data, revising the manuscript and final approval of the article	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4972485	27333048	HJ	7	Participant recruitment, acquisition of data, revising the manuscript and final approval of the article 6	Participant recruitment, acquisition of data, revising the manuscript and final approval of the article 6	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4972485	27333048	JB	7	Participant recruitment, acquisition of data, revising the manuscript and final approval of the article 32. Yamazaki K: Participant recruitment, acquisition of data, revising the manuscript and final approval of the article 33. Kim	Participant recruitment, acquisition of data, revising the manuscript and final approval of the article 32. Yamazaki K: Participant recruitment, acquisition of data, revising the manuscript and final approval of the article 33. Kim	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4972485	27333048	JJ	7	Participant recruitment, acquisition of data, revising the manuscript and final approval of the article 23. Kasetsermwiriya W: Participant recruitment, acquisition of data, revising the manuscript and final approval of the article 24. Ragunath K: Participant recruitment, acquisition of data, revising the manuscript and final approval of the article 25. Kim	Participant recruitment, acquisition of data, revising the manuscript and final approval of the article 23. Kasetsermwiriya W: Participant recruitment, acquisition of data, revising the manuscript and final approval of the article 24. Ragunath K: Participant recruitment, acquisition of data, revising the manuscript and final approval of the article 25. Kim	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4972485	27333048	LF	7	Participant recruitment, acquisition of data, revising the manuscript and final approval of the article 22. Bonilla	Participant recruitment, acquisition of data, revising the manuscript and final approval of the article 22. Bonilla	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4972485	27333048	MM	7	Participant recruitment, acquisition of data, revising the manuscript and final approval of the article 30. Iacopini F: Participant recruitment, acquisition of data, revising the manuscript and final approval of the article 31. So	Participant recruitment, acquisition of data, revising the manuscript and final approval of the article 30. Iacopini F: Participant recruitment, acquisition of data, revising the manuscript and final approval of the article 31. So	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4972485	27333048	Piedra Carvajal	7	Participant recruitment, acquisition of data, revising the manuscript and final approval of the article 38. Hayward	Participant recruitment, acquisition of data, revising the manuscript and final approval of the article 38. Hayward	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4972485	27333048	SE	7	Participant recruitment, acquisition of data, revising the manuscript and final approval of the article 26. Marini M: Participant recruitment, acquisition of data, revising the manuscript and final approval of the article 27. Li H: Participant recruitment, acquisition of data, revising the manuscript and final approval of the article 28. Cimmino	Participant recruitment, acquisition of data, revising the manuscript and final approval of the article 26. Marini M: Participant recruitment, acquisition of data, revising the manuscript and final approval of the article 27. Li H: Participant recruitment, acquisition of data, revising the manuscript and final approval of the article 28. Cimmino	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4972485	27333048	SH	7	Participant recruitment, acquisition of data, revising the manuscript and final approval of the article 12. Avendano	Participant recruitment, acquisition of data, revising the manuscript and final approval of the article 12. Avendano	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4972485	27333048	TL	7	Participant recruitment, acquisition of data, revising the manuscript and final approval of the article 35. Milhomem-Cardoso	Participant recruitment, acquisition of data, revising the manuscript and final approval of the article 35. Milhomem-Cardoso	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4972485	27333048	WA	7	Participant recruitment, acquisition of data, revising the manuscript and final approval of the article 38. Hayward	Participant recruitment, acquisition of data, revising the manuscript and final approval of the article 38. Hayward	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5502257	28740503	AJ	2	conceptualized and designed the research and edited manuscript	conceptualized and designed the research and edited manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
4403926	25894234	AKB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4403926	25894234	CRP	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4403926	25894234	CRP	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4403926	25894234	MK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4403926	25894234	PKB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4403926	25894234	PNCR	PLoS5	Clinical characteristic measurement	Clinical characteristic measurement	Performed the experiments	Investigation	YES
4403926	25894234	RA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Clinical characteristic measurement	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403926	25894234	RA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Clinical characteristic measurement	Performed the experiments	Performed the experiments	Investigation	YES
4403926	25894234	RA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Clinical characteristic measurement	Analyzed the data	Analyzed the data	Formal analysis	YES
4403926	25894234	RA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Clinical characteristic measurement	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403926	25894234	RA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Clinical characteristic measurement	Clinical characteristic measurement	Performed the experiments	Investigation	YES
4403926	25894234	SKB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403926	25894234	SKB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403926	25894234	SKB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403926	25894234	SKN	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4403926	25894234	SM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4296051	25591915	AD	2	coded and analyzed the data	coded and analyzed the data	Analyzed the data	Data curation|Formal analysis	YES
4296051	25591915	All authors	2	were involved in study implementation|provided critical interpretation of the data and approved the final manuscript	were involved in study implementation	Performed the experiments	Investigation	YES
4296051	25591915	All authors	2	were involved in study implementation|provided critical interpretation of the data and approved the final manuscript	provided critical interpretation of the data and approved the final manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
4296051	25591915	CP	2	coded and analyzed the data	coded and analyzed the data	Analyzed the data	Data curation|Formal analysis	YES
4296051	25591915	HB	2	coded and analyzed the data	coded and analyzed the data	Analyzed the data	Data curation|Formal analysis	YES
4296051	25591915	JAD	2	conceptualized and designed the study|coded and analyzed the data	conceptualized and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4296051	25591915	JAD	2	conceptualized and designed the study|coded and analyzed the data	coded and analyzed the data	Analyzed the data	Data curation|Formal analysis	YES
4972521	27333045	J.H.Y.	CRediT	Methodology|Investigation|Formal analysis|Writing-original draft|Funding acquisition	Methodology	Performed the experiments	Methodology	YES
4972521	27333045	J.H.Y.	CRediT	Methodology|Investigation|Formal analysis|Writing-original draft|Funding acquisition	Investigation	Performed the experiments	Investigation	YES
4972521	27333045	J.H.Y.	CRediT	Methodology|Investigation|Formal analysis|Writing-original draft|Funding acquisition	Formal analysis	Analyzed the data	Formal analysis	YES
4972521	27333045	J.H.Y.	CRediT	Methodology|Investigation|Formal analysis|Writing-original draft|Funding acquisition	Writing-original draft	Wrote the paper	Writing - Original Draft	YES
4972521	27333045	J.H.Y.	CRediT	Methodology|Investigation|Formal analysis|Writing-original draft|Funding acquisition	Funding acquisition	-	Funding acquisition	YES
4972521	27333045	J.W.E.	CRediT	Formal analysis	Formal analysis	Analyzed the data	Formal analysis	YES
4972521	27333045	J.Y.L.	CRediT	Writing-review & editing	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
4972521	27333045	O.K.	CRediT	Formal analysis	Formal analysis	Analyzed the data	Formal analysis	YES
4972521	27333045	S.W.N.	CRediT	Writing-review & editing	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
4972521	27333045	W.S.C.	CRediT	Formal analysis	Formal analysis	Analyzed the data	Formal analysis	YES
4972521	27333045	W.S.P.	CRediT	Methodology|Writing-original draft|Funding acquisition|Supervision	Methodology	Performed the experiments	Methodology	YES
4972521	27333045	W.S.P.	CRediT	Methodology|Writing-original draft|Funding acquisition|Supervision	Writing-original draft	Wrote the paper	Writing - Original Draft	YES
4972521	27333045	W.S.P.	CRediT	Methodology|Writing-original draft|Funding acquisition|Supervision	Funding acquisition	-	Funding acquisition	YES
4972521	27333045	W.S.P.	CRediT	Methodology|Writing-original draft|Funding acquisition|Supervision	Supervision	-	Supervision	YES
5084067	27198982	All authors	2	have given approval to the final version of the manuscript	have given approval to the final version of the manuscript	-	-	NO
5210266	28049478	All authors	2	contributed to and approved the final version of the manuscript	contributed to and approved the final version of the manuscript	-	-	NO
5210266	28049478	EPC	2	participated in study design, performed the rt-qpcr validation assay, carried out comparative data analysis, and drafted the manuscript	participated in study design, performed the rt-qpcr validation assay, carried out comparative data analysis, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Validation|Writing - Original Draft	YES
5210266	28049478	FSP	2	performed the sequence assembly, annotation, analysis of differential expression, phylogenetic analysis, and helped to draft the manuscript	performed the sequence assembly, annotation, analysis of differential expression, phylogenetic analysis, and helped to draft the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Formal analysis|Investigation|Writing - Original Draft	YES
5210266	28049478	JBLS	2	prepared samples and performed the rt-qpcr validation assay	prepared samples and performed the rt-qpcr validation assay	Performed the experiments	Investigation|Validation	YES
5210266	28049478	LAB	2	conceived and designed the study, prepared samples for sequencing, conducted the divergence analysis, and helped prepare the manuscript	conceived and designed the study, prepared samples for sequencing, conducted the divergence analysis, and helped prepare the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5210266	28049478	LAM	2	conceived and designed the study, drafted the manuscript and supervised the research	conceived and designed the study, drafted the manuscript and supervised the research	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Supervision|Writing - Original Draft	YES
5210266	28049478	MHFS	2	helped to design the study, and prepared rna libraries for sequencing	helped to design the study, and prepared rna libraries for sequencing	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5502268	28740500	JL	1	Revised the manuscript	Revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5502268	28740500	LZ	1	Revised the manuscript	Revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4403928	25893968	AB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403928	25893968	AB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403928	25893968	AB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403928	25893968	AB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403928	25893968	AD	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4403928	25893968	AD	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403928	25893968	DEM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4403928	25893968	DEM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403928	25893968	GSB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403928	25893968	GSB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403928	25893968	GSB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403928	25893968	GSB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403928	25893968	NV	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4403928	25893968	NV	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4403928	25893968	NV	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403928	25893968	PP	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4403928	25893968	PP	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4403928	25893968	PP	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403928	25893968	SH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4403928	25893968	SH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4403928	25893968	SH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403928	25893968	VN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403928	25893968	VN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4403928	25893968	VN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403928	25893968	VN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403928	25893968	VN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6333916	30675363	AM	2	involved in data acquisition|involved in data analysis/interpretation|involved in statistical analysis|drafted initial manuscript	involved in data acquisition	Performed the experiments	Investigation	YES
6333916	30675363	AM	2	involved in data acquisition|involved in data analysis/interpretation|involved in statistical analysis|drafted initial manuscript	involved in data analysis/interpretation	Analyzed the data	Formal analysis	YES
6333916	30675363	AM	2	involved in data acquisition|involved in data analysis/interpretation|involved in statistical analysis|drafted initial manuscript	involved in statistical analysis	Analyzed the data	Formal analysis	YES
6333916	30675363	AM	2	involved in data acquisition|involved in data analysis/interpretation|involved in statistical analysis|drafted initial manuscript	drafted initial manuscript	Wrote the paper	Writing - Original Draft	YES
6333916	30675363	DB	2	involved in statistical analysis|reviewed and revised manuscript	involved in statistical analysis	Analyzed the data	Formal analysis	YES
6333916	30675363	DB	2	involved in statistical analysis|reviewed and revised manuscript	reviewed and revised manuscript	Wrote the paper	Writing - Review & Editing	YES
6333916	30675363	EGL	2	contributed to research idea and study design	contributed to research idea and study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6333916	30675363	Each author	2	contributed important intellectual content during manuscript drafting or revision and accepts accountability for the overall work by ensuring that questions pertaining to the accuracy or integrity of any portion of the work are appropriately investigated and resolved	contributed important intellectual content during manuscript drafting or revision and accepts accountability for the overall work by ensuring that questions pertaining to the accuracy or integrity of any portion of the work are appropriately investigated and resolved	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6333916	30675363	HC	2	contributed to research idea and study design|involved in data analysis/interpretation|involved in statistical analysis|reviewed and revised manuscript|involved in supervision or mentorship	contributed to research idea and study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6333916	30675363	HC	2	contributed to research idea and study design|involved in data analysis/interpretation|involved in statistical analysis|reviewed and revised manuscript|involved in supervision or mentorship	involved in data analysis/interpretation	Analyzed the data	Formal analysis	YES
6333916	30675363	HC	2	contributed to research idea and study design|involved in data analysis/interpretation|involved in statistical analysis|reviewed and revised manuscript|involved in supervision or mentorship	involved in statistical analysis	Analyzed the data	Formal analysis	YES
6333916	30675363	HC	2	contributed to research idea and study design|involved in data analysis/interpretation|involved in statistical analysis|reviewed and revised manuscript|involved in supervision or mentorship	reviewed and revised manuscript	Wrote the paper	Writing - Review & Editing	YES
6333916	30675363	HC	2	contributed to research idea and study design|involved in data analysis/interpretation|involved in statistical analysis|reviewed and revised manuscript|involved in supervision or mentorship	involved in supervision or mentorship	-	Supervision	YES
6333916	30675363	LER	2	involved in data acquisition|involved in data analysis/interpretation|drafted initial manuscript	involved in data acquisition	Performed the experiments	Investigation	YES
6333916	30675363	LER	2	involved in data acquisition|involved in data analysis/interpretation|drafted initial manuscript	involved in data analysis/interpretation	Analyzed the data	Formal analysis	YES
6333916	30675363	LER	2	involved in data acquisition|involved in data analysis/interpretation|drafted initial manuscript	drafted initial manuscript	Wrote the paper	Writing - Original Draft	YES
6333916	30675363	LL	2	contributed to research idea and study design|involved in data analysis/interpretation|reviewed and revised manuscript	contributed to research idea and study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6333916	30675363	LL	2	contributed to research idea and study design|involved in data analysis/interpretation|reviewed and revised manuscript	involved in data analysis/interpretation	Analyzed the data	Formal analysis	YES
6333916	30675363	LL	2	contributed to research idea and study design|involved in data analysis/interpretation|reviewed and revised manuscript	reviewed and revised manuscript	Wrote the paper	Writing - Review & Editing	YES
6333916	30675363	NB	2	contributed to research idea and study design|involved in data analysis/interpretation|reviewed and revised manuscript|involved in supervision or mentorship	contributed to research idea and study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6333916	30675363	NB	2	contributed to research idea and study design|involved in data analysis/interpretation|reviewed and revised manuscript|involved in supervision or mentorship	involved in data analysis/interpretation	Analyzed the data	Formal analysis	YES
6333916	30675363	NB	2	contributed to research idea and study design|involved in data analysis/interpretation|reviewed and revised manuscript|involved in supervision or mentorship	reviewed and revised manuscript	Wrote the paper	Writing - Review & Editing	YES
6333916	30675363	NB	2	contributed to research idea and study design|involved in data analysis/interpretation|reviewed and revised manuscript|involved in supervision or mentorship	involved in supervision or mentorship	-	Supervision	YES
6333916	30675363	QD	2	involved in data acquisition|involved in data analysis/interpretation|involved in statistical analysis|drafted initial manuscript	involved in data acquisition	Performed the experiments	Investigation	YES
6333916	30675363	QD	2	involved in data acquisition|involved in data analysis/interpretation|involved in statistical analysis|drafted initial manuscript	involved in data analysis/interpretation	Analyzed the data	Formal analysis	YES
6333916	30675363	QD	2	involved in data acquisition|involved in data analysis/interpretation|involved in statistical analysis|drafted initial manuscript	involved in statistical analysis	Analyzed the data	Formal analysis	YES
6333916	30675363	QD	2	involved in data acquisition|involved in data analysis/interpretation|involved in statistical analysis|drafted initial manuscript	drafted initial manuscript	Wrote the paper	Writing - Original Draft	YES
6333916	30675363	SA	2	involved in data acquisition|involved in data analysis/interpretation|drafted initial manuscript	involved in data acquisition	Performed the experiments	Investigation	YES
6333916	30675363	SA	2	involved in data acquisition|involved in data analysis/interpretation|drafted initial manuscript	involved in data analysis/interpretation	Analyzed the data	Formal analysis	YES
6333916	30675363	SA	2	involved in data acquisition|involved in data analysis/interpretation|drafted initial manuscript	drafted initial manuscript	Wrote the paper	Writing - Original Draft	YES
4972528	27333041	BM	PLoS52	designed the study|analyzed data|developed the bioinformatics analysis pipeline|wrote the paper	designed the study	Conceived and designed the experiments	Methodology	YES
4972528	27333041	BM	PLoS52	designed the study|analyzed data|developed the bioinformatics analysis pipeline|wrote the paper	analyzed data	Analyzed the data	Formal analysis	YES
4972528	27333041	BM	PLoS52	designed the study|analyzed data|developed the bioinformatics analysis pipeline|wrote the paper	developed the bioinformatics analysis pipeline	-	Formal analysis	YES
4972528	27333041	BM	PLoS52	designed the study|analyzed data|developed the bioinformatics analysis pipeline|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4972528	27333041	CCB	PLoS52	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
4972528	27333041	GDC	PLoS52	designed the study|analyzed data|developed the bioinformatics analysis pipeline|prepared the figures|wrote the paper	designed the study	Conceived and designed the experiments	Methodology	YES
4972528	27333041	GDC	PLoS52	designed the study|analyzed data|developed the bioinformatics analysis pipeline|prepared the figures|wrote the paper	analyzed data	Analyzed the data	Formal analysis	YES
4972528	27333041	GDC	PLoS52	designed the study|analyzed data|developed the bioinformatics analysis pipeline|prepared the figures|wrote the paper	developed the bioinformatics analysis pipeline	-	Formal analysis	YES
4972528	27333041	GDC	PLoS52	designed the study|analyzed data|developed the bioinformatics analysis pipeline|prepared the figures|wrote the paper	prepared the figures	-	Visualization	YES
4972528	27333041	GDC	PLoS52	designed the study|analyzed data|developed the bioinformatics analysis pipeline|prepared the figures|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4972528	27333041	JRA	PLoS52	designed the study|obtained and organized clinical, radiological imaging and macrophotographic data|analyzed data|wrote the paper	designed the study	Conceived and designed the experiments	Methodology	YES
4972528	27333041	JRA	PLoS52	designed the study|obtained and organized clinical, radiological imaging and macrophotographic data|analyzed data|wrote the paper	obtained and organized clinical, radiological imaging and macrophotographic data	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
4972528	27333041	JRA	PLoS52	designed the study|obtained and organized clinical, radiological imaging and macrophotographic data|analyzed data|wrote the paper	analyzed data	Analyzed the data	Formal analysis	YES
4972528	27333041	JRA	PLoS52	designed the study|obtained and organized clinical, radiological imaging and macrophotographic data|analyzed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4972528	27333041	KPJ	PLoS52	designed the study|supervised the project|wrote the paper	designed the study	Conceived and designed the experiments	Methodology	YES
4972528	27333041	KPJ	PLoS52	designed the study|supervised the project|wrote the paper	supervised the project	-	Supervision	YES
4972528	27333041	KPJ	PLoS52	designed the study|supervised the project|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4972528	27333041	MEW	PLoS52	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
4972528	27333041	MM	PLoS52	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
4972528	27333041	NJS	PLoS52	designed the study|supervised the project|wrote the paper	designed the study	Conceived and designed the experiments	Methodology	YES
4972528	27333041	NJS	PLoS52	designed the study|supervised the project|wrote the paper	supervised the project	-	Supervision	YES
4972528	27333041	NJS	PLoS52	designed the study|supervised the project|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4972528	27333041	NML	PLoS52	developed the bioinformatics analysis pipeline|supervised the project|wrote the paper	developed the bioinformatics analysis pipeline	-	Formal analysis	YES
4972528	27333041	NML	PLoS52	developed the bioinformatics analysis pipeline|supervised the project|wrote the paper	supervised the project	-	Supervision	YES
4972528	27333041	NML	PLoS52	developed the bioinformatics analysis pipeline|supervised the project|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4972528	27333041	OEO	PLoS52	performed radiological imaging analyses	performed radiological imaging analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
4972528	27333041	RDW	PLoS52	designed the study|analyzed data|supervised the project|wrote the paper	designed the study	Conceived and designed the experiments	Methodology	YES
4972528	27333041	RDW	PLoS52	designed the study|analyzed data|supervised the project|wrote the paper	analyzed data	Analyzed the data	Formal analysis	YES
4972528	27333041	RDW	PLoS52	designed the study|analyzed data|supervised the project|wrote the paper	supervised the project	-	Supervision	YES
4972528	27333041	RDW	PLoS52	designed the study|analyzed data|supervised the project|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4972528	27333041	TC	PLoS52	extracted dna and carried out molecular analyses	extracted dna and carried out molecular analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4972528	27333041	WM	PLoS52	designed the study|took photomicrographs|analyzed data|developed the bioinformatics analysis pipeline|supervised the project|wrote the paper	designed the study	Conceived and designed the experiments	Methodology	YES
4972528	27333041	WM	PLoS52	designed the study|took photomicrographs|analyzed data|developed the bioinformatics analysis pipeline|supervised the project|wrote the paper	took photomicrographs	-	-	NO
4972528	27333041	WM	PLoS52	designed the study|took photomicrographs|analyzed data|developed the bioinformatics analysis pipeline|supervised the project|wrote the paper	analyzed data	Analyzed the data	Formal analysis	YES
4972528	27333041	WM	PLoS52	designed the study|took photomicrographs|analyzed data|developed the bioinformatics analysis pipeline|supervised the project|wrote the paper	developed the bioinformatics analysis pipeline	-	Formal analysis	YES
4972528	27333041	WM	PLoS52	designed the study|took photomicrographs|analyzed data|developed the bioinformatics analysis pipeline|supervised the project|wrote the paper	supervised the project	-	Supervision	YES
4972528	27333041	WM	PLoS52	designed the study|took photomicrographs|analyzed data|developed the bioinformatics analysis pipeline|supervised the project|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4297925	25598476	JLF	2	conducted the literature review and wrote the first draft of the manuscript	conducted the literature review and wrote the first draft of the manuscript	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
4297925	25598476	PG	2	updated the literature review and revised the manuscript	updated the literature review and revised the manuscript	Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4523151	26257905	CFC	7	Writing, Critical Revision, Final Approval	Writing, Critical Revision, Final Approval	Wrote the paper	Writing - Review & Editing	YES
4523151	26257905	EE	7	Critical Revision, Final Approval	Critical Revision, Final Approval	Wrote the paper	Writing - Review & Editing	YES
4523151	26257905	NB	7	Concept, Design, Critical Revision, Final Approval	Concept, Design, Critical Revision, Final Approval	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
4523151	26257905	RAA	7	Concept, Design, Critical Revision, Final Approval	Concept, Design, Critical Revision, Final Approval	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5210274	28049432	GK	2	designed, developed and validated the screening protocols used for analyses and verification of mutant phenotypes|participated in the transposon screen	designed, developed and validated the screening protocols used for analyses and verification of mutant phenotypes	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology|Validation	YES
5210274	28049432	GK	2	designed, developed and validated the screening protocols used for analyses and verification of mutant phenotypes|participated in the transposon screen	participated in the transposon screen	Performed the experiments	Investigation	YES
5210274	28049432	HE	2	supervised the strain and library construction and annotated the mutants to functions|participated in the initiation and design of the study and in the writing of the manuscript	supervised the strain and library construction and annotated the mutants to functions	Performed the experiments	Investigation|Supervision	YES
5210274	28049432	HE	2	supervised the strain and library construction and annotated the mutants to functions|participated in the initiation and design of the study and in the writing of the manuscript	participated in the initiation and design of the study and in the writing of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5210274	28049432	HS	2	designed, developed and validated the screening protocols used for analyses and verification of mutant phenotypes|participated in the transposon screen|participated in the initiation and design of the study and in the writing of the manuscript	designed, developed and validated the screening protocols used for analyses and verification of mutant phenotypes	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology|Validation	YES
5210274	28049432	HS	2	designed, developed and validated the screening protocols used for analyses and verification of mutant phenotypes|participated in the transposon screen|participated in the initiation and design of the study and in the writing of the manuscript	participated in the transposon screen	Performed the experiments	Investigation	YES
5210274	28049432	HS	2	designed, developed and validated the screening protocols used for analyses and verification of mutant phenotypes|participated in the transposon screen|participated in the initiation and design of the study and in the writing of the manuscript	participated in the initiation and design of the study and in the writing of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5210274	28049432	MS	2	constructed the strain, transposon vector and library|participated in the transposon screen	constructed the strain, transposon vector and library	Performed the experiments	Investigation	YES
5210274	28049432	MS	2	constructed the strain, transposon vector and library|participated in the transposon screen	participated in the transposon screen	Performed the experiments	Investigation	YES
5210274	28049432	SV	2	participated in the initiation and design of the study and in the writing of the manuscript	participated in the initiation and design of the study and in the writing of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5210274	28049432	TE	2	participated in the initiation and design of the study and in the writing of the manuscript	participated in the initiation and design of the study and in the writing of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5210274	28049432	TK	2	identified and complemented the phobr mutants	identified and complemented the phobr mutants	Performed the experiments	Investigation	YES
5210274	28049432	YQS	2	identified inactivated genes and complemented some mutants	identified inactivated genes and complemented some mutants	Performed the experiments	Investigation	YES
6343018	30693087	A.M.V.	1	Participated in research design|Performed data analysis	Participated in research design	Conceived and designed the experiments	-	YES
6343018	30693087	A.M.V.	1	Participated in research design|Performed data analysis	Performed data analysis	Analyzed the data	Formal analysis	YES
6343018	30693087	E.W.	1	Participated in research design|Performed data analysis|Wrote or contributed to the writing of the manuscript	Participated in research design	Conceived and designed the experiments	-	YES
6343018	30693087	E.W.	1	Participated in research design|Performed data analysis|Wrote or contributed to the writing of the manuscript	Performed data analysis	Analyzed the data	Formal analysis	YES
6343018	30693087	E.W.	1	Participated in research design|Performed data analysis|Wrote or contributed to the writing of the manuscript	Wrote or contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
6343018	30693087	I.T.	1	Participated in research design|Performed data analysis|Wrote or contributed to the writing of the manuscript	Participated in research design	Conceived and designed the experiments	-	YES
6343018	30693087	I.T.	1	Participated in research design|Performed data analysis|Wrote or contributed to the writing of the manuscript	Performed data analysis	Analyzed the data	Formal analysis	YES
6343018	30693087	I.T.	1	Participated in research design|Performed data analysis|Wrote or contributed to the writing of the manuscript	Wrote or contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
6343018	30693087	J.G.	1	Contributed new reagents or analytic tools	Contributed new reagents or analytic tools	Contributed reagents/materials/analysis tools	Resources	YES
6343018	30693087	S.K.	1	Participated in research design|Performed data analysis|Wrote or contributed to the writing of the manuscript	Participated in research design	Conceived and designed the experiments	-	YES
6343018	30693087	S.K.	1	Participated in research design|Performed data analysis|Wrote or contributed to the writing of the manuscript	Performed data analysis	Analyzed the data	Formal analysis	YES
6343018	30693087	S.K.	1	Participated in research design|Performed data analysis|Wrote or contributed to the writing of the manuscript	Wrote or contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
6343018	30693087	S.Z.	1	Participated in research design|Performed data analysis|Wrote or contributed to the writing of the manuscript	Participated in research design	Conceived and designed the experiments	-	YES
6343018	30693087	S.Z.	1	Participated in research design|Performed data analysis|Wrote or contributed to the writing of the manuscript	Performed data analysis	Analyzed the data	Formal analysis	YES
6343018	30693087	S.Z.	1	Participated in research design|Performed data analysis|Wrote or contributed to the writing of the manuscript	Wrote or contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
6343018	30693087	U.K.	1	Contributed new reagents or analytic tools	Contributed new reagents or analytic tools	Contributed reagents/materials/analysis tools	Resources	YES
4302168	25609215	All authors	2	contributed to the critical review of the manuscript	contributed to the critical review of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4302168	25609215	BLH	2	took initiative to write the manuscript|wrote the first draft of the manuscript	took initiative to write the manuscript	Wrote the paper	Writing - Original Draft	YES
4302168	25609215	BLH	2	took initiative to write the manuscript|wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
4302168	25609215	CE	2	took initiative to write the manuscript	took initiative to write the manuscript	Wrote the paper	Writing - Original Draft	YES
4302168	25609215	CW	2	took initiative to write the manuscript	took initiative to write the manuscript	Wrote the paper	Writing - Original Draft	YES
4302168	25609215	JSO	2	contributed to writing the manuscript	contributed to writing the manuscript	Wrote the paper	Writing - Original Draft	YES
4302168	25609215	SJ	2	contributed to writing the manuscript	contributed to writing the manuscript	Wrote the paper	Writing - Original Draft	YES
4403985	25893644	CHL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403985	25893644	CPW	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4403985	25893644	CPW	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403985	25893644	FMC	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403985	25893644	FMC	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403985	25893644	KTL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4403985	25893644	LFL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403985	25893644	LLHH	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4403985	25893644	PYC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4403985	25893644	THY	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403985	25893644	WCH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4403985	25893644	WHT	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403985	25893644	WHT	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4403985	25893644	WHT	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403985	25893644	WHT	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403985	25893644	WTL	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403985	25893644	YJL	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5502274	28740499	AD	2	carried out the central metabolite analysis	carried out the central metabolite analysis	Performed the experiments	Investigation	YES
5502274	28740499	AF	2	supervised the central metabolite analysis and critically revised the manuscript	supervised the central metabolite analysis and critically revised the manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
5502274	28740499	BB	2	performed the field experiment	performed the field experiment	Performed the experiments	Investigation	YES
5502274	28740499	DCJW	2	carried out part of the transcriptome data analysis, the network analysis, and drafted part of the manuscript	carried out part of the transcriptome data analysis, the network analysis, and drafted part of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5502274	28740499	EP	2	coordinated the field experiments	coordinated the field experiments	Performed the experiments	Investigation|Project administration	YES
5502274	28740499	FM	2	participated in the design of the study, supervised the metabolite analysis, and critically revised the manuscript	participated in the design of the study, supervised the metabolite analysis, and critically revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Review & Editing	YES
5502274	28740499	JCH	2	carried out the anthocyanin analysis	carried out the anthocyanin analysis	Performed the experiments	Investigation	YES
5502274	28740499	SDC	2	conceived the study, coordinated the experiments, supervised the field experiment, transcriptome analysis, and network analysis, interpreted the results, and drafted part of the manuscript	conceived the study, coordinated the experiments, supervised the field experiment, transcriptome analysis, and network analysis, interpreted the results, and drafted part of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Project administration|Supervision|Writing - Original Draft	YES
5502274	28740499	SS	2	participated in the design of the study, carried out the specialized metabolite analyses, rna extractions, part of the transcriptome data analysis, and drafted part of the manuscript	participated in the design of the study, carried out the specialized metabolite analyses, rna extractions, part of the transcriptome data analysis, and drafted part of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5210278	28049430	KP	2	performed data analyses and interpretations	performed data analyses and interpretations	Analyzed the data	Formal analysis	YES
5210278	28049430	MS	2	performed data analyses and interpretations	performed data analyses and interpretations	Analyzed the data	Formal analysis	YES
5210278	28049430	PSA	2	performed data analyses and interpretations	performed data analyses and interpretations	Analyzed the data	Formal analysis	YES
5210278	28049430	RHO	2	performed data analyses and interpretations	performed data analyses and interpretations	Analyzed the data	Formal analysis	YES
5210278	28049430	TR	2	performed data analyses and interpretations|wrote the manuscript which finally was edited and approved by all authors	performed data analyses and interpretations	Analyzed the data	Formal analysis	YES
5210278	28049430	TR	2	performed data analyses and interpretations|wrote the manuscript which finally was edited and approved by all authors	wrote the manuscript which finally was edited and approved by all authors	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6349072	30705757	A.B.	2	performed the simulations that concern the in vivo and in vitro cases, respectively	performed the simulations that concern the in vivo and in vitro cases, respectively	Performed the experiments	Formal analysis|Investigation	YES
6349072	30705757	A.S.	2	performed the simulations that concern the in vivo and in vitro cases, respectively	performed the simulations that concern the in vivo and in vitro cases, respectively	Performed the experiments	Formal analysis|Investigation	YES
6349072	30705757	Both authors	2	equally contributed in the writing of the manuscript	equally contributed in the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
4302169	25609214	Iryna Zablotska	2	provided oversight in the design, implementation and interpretation of findings and provided significant input into the preparation of this manuscript	provided oversight in the design, implementation and interpretation of findings and provided significant input into the preparation of this manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Supervision|Writing - Original Draft	YES
4302169	25609214	Lisa Maher	2	provided oversight in the design, implementation and interpretation of findings and provided significant input into the preparation of this manuscript	provided oversight in the design, implementation and interpretation of findings and provided significant input into the preparation of this manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Supervision|Writing - Original Draft	YES
4302169	25609214	Nga Thi Thu	2	contributed significant efforts in the development and conduct of the review, performance of the statistical analysis and drafting of the manuscript	contributed significant efforts in the development and conduct of the review, performance of the statistical analysis and drafting of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
4403986	25893248	KH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403986	25893248	KH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4403986	25893248	KH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403986	25893248	KH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403986	25893248	KH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403986	25893248	KK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403986	25893248	KK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4403986	25893248	KK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403986	25893248	KK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403986	25893248	KK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403986	25893248	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403986	25893248	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4403986	25893248	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403986	25893248	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403986	25893248	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403986	25893248	TH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403986	25893248	TH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4403986	25893248	TH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403986	25893248	TH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403986	25893248	TH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5210286	28049416	FW	2	assisted with the conducted the bulk of experiments with	assisted with the conducted the bulk of experiments with	Performed the experiments	Investigation	YES
5210286	28049416	GC	2	analysed data	analysed data	Analyzed the data	Formal analysis	YES
5210286	28049416	GS	2	analysed data	analysed data	Analyzed the data	Formal analysis	YES
5210286	28049416	GW	2	supervised the experiments	supervised the experiments	-	Supervision	YES
5210286	28049416	MB	2	conducted the bulk of experiments with|analysed data	conducted the bulk of experiments with	Performed the experiments	Investigation	YES
5210286	28049416	MB	2	conducted the bulk of experiments with|analysed data	analysed data	Analyzed the data	Formal analysis	YES
5210286	28049416	MM	2	conducted the bulk of experiments with|analysed data	conducted the bulk of experiments with	Performed the experiments	Investigation	YES
5210286	28049416	MM	2	conducted the bulk of experiments with|analysed data	analysed data	Analyzed the data	Formal analysis	YES
5210286	28049416	MZ	2	designed research|assisted with the conducted the bulk of experiments with|supervised the experiments|analysed data|wrote the article with contributions of all the authors	designed research	Conceived and designed the experiments	Methodology	YES
5210286	28049416	MZ	2	designed research|assisted with the conducted the bulk of experiments with|supervised the experiments|analysed data|wrote the article with contributions of all the authors	assisted with the conducted the bulk of experiments with	Performed the experiments	Investigation	YES
5210286	28049416	MZ	2	designed research|assisted with the conducted the bulk of experiments with|supervised the experiments|analysed data|wrote the article with contributions of all the authors	supervised the experiments	-	Supervision	YES
5210286	28049416	MZ	2	designed research|assisted with the conducted the bulk of experiments with|supervised the experiments|analysed data|wrote the article with contributions of all the authors	analysed data	Analyzed the data	Formal analysis	YES
5210286	28049416	MZ	2	designed research|assisted with the conducted the bulk of experiments with|supervised the experiments|analysed data|wrote the article with contributions of all the authors	wrote the article with contributions of all the authors	Wrote the paper	Writing - Original Draft	YES
5210286	28049416	PH	2	supervised the experiments|wrote the article with contributions of all the authors	supervised the experiments	-	Supervision	YES
5210286	28049416	PH	2	supervised the experiments|wrote the article with contributions of all the authors	wrote the article with contributions of all the authors	Wrote the paper	Writing - Original Draft	YES
5210286	28049416	SS	2	supervised the experiments|wrote the article with contributions of all the authors	supervised the experiments	-	Supervision	YES
5210286	28049416	SS	2	supervised the experiments|wrote the article with contributions of all the authors	wrote the article with contributions of all the authors	Wrote the paper	Writing - Original Draft	YES
5210286	28049416	XL	2	conducted the bulk of experiments with|analysed data|wrote the article with contributions of all the authors	conducted the bulk of experiments with	Performed the experiments	Investigation	YES
5210286	28049416	XL	2	conducted the bulk of experiments with|analysed data|wrote the article with contributions of all the authors	analysed data	Analyzed the data	Formal analysis	YES
5210286	28049416	XL	2	conducted the bulk of experiments with|analysed data|wrote the article with contributions of all the authors	wrote the article with contributions of all the authors	Wrote the paper	Writing - Original Draft	YES
5210286	28049416	YF	2	conducted the bulk of experiments with|analysed data|wrote the article with contributions of all the authors	conducted the bulk of experiments with	Performed the experiments	Investigation	YES
5210286	28049416	YF	2	conducted the bulk of experiments with|analysed data|wrote the article with contributions of all the authors	analysed data	Analyzed the data	Formal analysis	YES
5210286	28049416	YF	2	conducted the bulk of experiments with|analysed data|wrote the article with contributions of all the authors	wrote the article with contributions of all the authors	Wrote the paper	Writing - Original Draft	YES
5210286	28049416	ZHC	2	designed research|assisted with the conducted the bulk of experiments with|supervised the experiments|analysed data|wrote the article with contributions of all the authors	designed research	Conceived and designed the experiments	Methodology	YES
5210286	28049416	ZHC	2	designed research|assisted with the conducted the bulk of experiments with|supervised the experiments|analysed data|wrote the article with contributions of all the authors	assisted with the conducted the bulk of experiments with	Performed the experiments	Investigation	YES
5210286	28049416	ZHC	2	designed research|assisted with the conducted the bulk of experiments with|supervised the experiments|analysed data|wrote the article with contributions of all the authors	supervised the experiments	-	Supervision	YES
5210286	28049416	ZHC	2	designed research|assisted with the conducted the bulk of experiments with|supervised the experiments|analysed data|wrote the article with contributions of all the authors	analysed data	Analyzed the data	Formal analysis	YES
5210286	28049416	ZHC	2	designed research|assisted with the conducted the bulk of experiments with|supervised the experiments|analysed data|wrote the article with contributions of all the authors	wrote the article with contributions of all the authors	Wrote the paper	Writing - Original Draft	YES
5502275	28740501	FC	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5502275	28740501	FM	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5502275	28740501	JF	PLoS52	designed the experiments|performed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5502275	28740501	JF	PLoS52	designed the experiments|performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5502275	28740501	PC	PLoS52	designed the experiments|wrote the paper	designed the experiments	Conceived and designed the experiments	Methodology	YES
5502275	28740501	PC	PLoS52	designed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5502275	28740501	SR	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
4403988	25894341	CYL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403988	25894341	CYL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403988	25894341	CYL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403988	25894341	HGC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4403988	25894341	PZL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403988	25894341	PZL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4403988	25894341	PZL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403988	25894341	PZL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403988	25894341	PZL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403988	25894341	WO	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4308659	25623930	ELJ	2	designed the research|performed experiments|contributed to interpretation of results and discussion|analyzed the data, prepared figures and prepared the manuscript|revised the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
4308659	25623930	ELJ	2	designed the research|performed experiments|contributed to interpretation of results and discussion|analyzed the data, prepared figures and prepared the manuscript|revised the manuscript	performed experiments	Performed the experiments	Investigation	YES
4308659	25623930	ELJ	2	designed the research|performed experiments|contributed to interpretation of results and discussion|analyzed the data, prepared figures and prepared the manuscript|revised the manuscript	contributed to interpretation of results and discussion	Analyzed the data	Formal analysis	YES
4308659	25623930	ELJ	2	designed the research|performed experiments|contributed to interpretation of results and discussion|analyzed the data, prepared figures and prepared the manuscript|revised the manuscript	analyzed the data, prepared figures and prepared the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Visualization|Writing - Original Draft	YES
4308659	25623930	ELJ	2	designed the research|performed experiments|contributed to interpretation of results and discussion|analyzed the data, prepared figures and prepared the manuscript|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4308659	25623930	HC	2	designed the research|performed experiments|contributed to interpretation of results and discussion|revised the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
4308659	25623930	HC	2	designed the research|performed experiments|contributed to interpretation of results and discussion|revised the manuscript	performed experiments	Performed the experiments	Investigation	YES
4308659	25623930	HC	2	designed the research|performed experiments|contributed to interpretation of results and discussion|revised the manuscript	contributed to interpretation of results and discussion	Analyzed the data	Formal analysis	YES
4308659	25623930	HC	2	designed the research|performed experiments|contributed to interpretation of results and discussion|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4308659	25623930	PS	2	contributed to interpretation of results and discussion|revised the manuscript	contributed to interpretation of results and discussion	Analyzed the data	Formal analysis	YES
4308659	25623930	PS	2	contributed to interpretation of results and discussion|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4308659	25623930	RC	2	designed the research|contributed to interpretation of results and discussion|analyzed the data, prepared figures and prepared the manuscript|revised the manuscript|is the principal investigator	designed the research	Conceived and designed the experiments	Methodology	YES
4308659	25623930	RC	2	designed the research|contributed to interpretation of results and discussion|analyzed the data, prepared figures and prepared the manuscript|revised the manuscript|is the principal investigator	contributed to interpretation of results and discussion	Analyzed the data	Formal analysis	YES
4308659	25623930	RC	2	designed the research|contributed to interpretation of results and discussion|analyzed the data, prepared figures and prepared the manuscript|revised the manuscript|is the principal investigator	analyzed the data, prepared figures and prepared the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Visualization|Writing - Original Draft	YES
4308659	25623930	RC	2	designed the research|contributed to interpretation of results and discussion|analyzed the data, prepared figures and prepared the manuscript|revised the manuscript|is the principal investigator	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4308659	25623930	RC	2	designed the research|contributed to interpretation of results and discussion|analyzed the data, prepared figures and prepared the manuscript|revised the manuscript|is the principal investigator	is the principal investigator	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
4308659	25623930	SNB	2	designed the research|contributed to interpretation of results and discussion|revised the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
4308659	25623930	SNB	2	designed the research|contributed to interpretation of results and discussion|revised the manuscript	contributed to interpretation of results and discussion	Analyzed the data	Formal analysis	YES
4308659	25623930	SNB	2	designed the research|contributed to interpretation of results and discussion|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4972561	27333030	A.A.	2	designed and performed the experiment presented in fig	designed and performed the experiment presented in fig	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4972561	27333030	A.C.V.	2	performed experiments presented in fig	performed experiments presented in fig	Performed the experiments	Investigation	YES
4972561	27333030	A.M.	2	provided important insight into the clinical practice and possible confounding factors	provided important insight into the clinical practice and possible confounding factors	-	-	NO
4972561	27333030	A.M.E.	2	designed and performed most of the cell culture experiments, analyzed the data and contributed to the writing of the manuscript	designed and performed most of the cell culture experiments, analyzed the data and contributed to the writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4972561	27333030	All authors	2	contributed to the final text and approved it	contributed to the final text and approved it	Wrote the paper	Writing - Original Draft	YES
4972561	27333030	C.D.	2	designed and performed the analyses of all registry-based data	designed and performed the analyses of all registry-based data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4972561	27333030	J.N.	2	contributed to the design of cell culture experiments	contributed to the design of cell culture experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4972561	27333030	J.S.	2	designed the experiments and analyzed the data presented in fig	designed the experiments and analyzed the data presented in fig	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
4972561	27333030	K.O.	2	provided important insight into the clinical practice and possible confounding factors	provided important insight into the clinical practice and possible confounding factors	-	-	NO
4972561	27333030	L.C.	2	assisted in the design of the registry-based studies	assisted in the design of the registry-based studies	Conceived and designed the experiments	Methodology	YES
4972561	27333030	M.J.	2	designed the study, analyzed the biological data and wrote the first draft of the manuscript	designed the study, analyzed the biological data and wrote the first draft of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4972561	27333030	N.H.T.P.	2	contributed to the design of cell culture experiments	contributed to the design of cell culture experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4972561	27333030	S.F.	2	designed the epidemiological analyses, analyzed the data and contributed to the writing the manuscript	designed the epidemiological analyses, analyzed the data and contributed to the writing the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5210311	28049433	ADH	2	performed the neutron irradiations and x-ray dosimetry and irradiations	performed the neutron irradiations and x-ray dosimetry and irradiations	Performed the experiments	Investigation	YES
5210311	28049433	CGB	2	performed the experiments and analyzed the primary data, interpreted the results and wrote the manuscript	performed the experiments and analyzed the primary data, interpreted the results and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5210311	28049433	GG	2	assisted in the neutron irradiations and in writing the manuscript	assisted in the neutron irradiations and in writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5210311	28049433	SAA	2	designed the study and contributed to data analysis and interpretation, and writing the manuscript	designed the study and contributed to data analysis and interpretation, and writing the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5502289	28740502	F-NX	PLoS52	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5502289	28740502	HQ	PLoS52	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5502289	28740502	L-JX	PLoS52	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5502289	28740502	LC	PLoS52	carried out the experiments|analyzed the data|wrote the manuscript	carried out the experiments	Performed the experiments	Investigation	YES
5502289	28740502	LC	PLoS52	carried out the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5502289	28740502	LC	PLoS52	carried out the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5502289	28740502	LH	PLoS52	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5502289	28740502	Q-FC	PLoS52	designed the study|analyzed the data	designed the study	Conceived and designed the experiments	Methodology	YES
5502289	28740502	Q-FC	PLoS52	designed the study|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5502289	28740502	SX	PLoS52	designed the study|analyzed the data|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5502289	28740502	SX	PLoS52	designed the study|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5502289	28740502	SX	PLoS52	designed the study|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5502289	28740502	Z-ZS	PLoS52	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
4523158	26257897	CFC	7	editing, and critical revisions	editing, and critical revisions	Wrote the paper	Writing - Review & Editing	YES
4523158	26257897	EE	7	writing initial draft, editing, and critical revisions	writing initial draft, editing, and critical revisions	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4475332	26097493	AC	2	participated in the project study design	participated in the project study design	Conceived and designed the experiments	Methodology	YES
4475332	26097493	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4475332	26097493	CD	2	conducted statistical analysis	conducted statistical analysis	Analyzed the data	Formal analysis	YES
4475332	26097493	CV	2	participated in the project study design|conducted statistical analysis	participated in the project study design	Conceived and designed the experiments	Methodology	YES
4475332	26097493	CV	2	participated in the project study design|conducted statistical analysis	conducted statistical analysis	Analyzed the data	Formal analysis	YES
4475332	26097493	EB	2	were involved in data acquisition	were involved in data acquisition	Performed the experiments	Investigation	YES
4475332	26097493	LTT	2	were involved in data acquisition	were involved in data acquisition	Performed the experiments	Investigation	YES
4475332	26097493	MB	2	were involved in data acquisition	were involved in data acquisition	Performed the experiments	Investigation	YES
4475332	26097493	MS	2	were involved in data acquisition	were involved in data acquisition	Performed the experiments	Investigation	YES
4475332	26097493	ST	2	were involved in data acquisition	were involved in data acquisition	Performed the experiments	Investigation	YES
4475332	26097493	SZ	2	were involved in data acquisition	were involved in data acquisition	Performed the experiments	Investigation	YES
4403989	25894561	GAN	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper|Review and critical feedback on manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403989	25894561	GAN	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper|Review and critical feedback on manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403989	25894561	GAN	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper|Review and critical feedback on manuscript	Review and critical feedback on manuscript	Wrote the paper	Writing - Review & Editing	YES
4403989	25894561	MHC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Review and critical feedback on manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403989	25894561	MHC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Review and critical feedback on manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4403989	25894561	MHC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Review and critical feedback on manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4403989	25894561	MHC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Review and critical feedback on manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403989	25894561	MHC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Review and critical feedback on manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403989	25894561	MHC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Review and critical feedback on manuscript	Review and critical feedback on manuscript	Wrote the paper	Writing - Review & Editing	YES
4403989	25894561	PAS	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper|Review and critical feedback on manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403989	25894561	PAS	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper|Review and critical feedback on manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403989	25894561	PAS	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper|Review and critical feedback on manuscript	Review and critical feedback on manuscript	Wrote the paper	Writing - Review & Editing	YES
4403989	25894561	RPH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403989	25894561	RPH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4403989	25894561	RPH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403989	25894561	RPH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5504165	28744293	DB	2	designed the experiments|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5504165	28744293	DB	2	designed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5504165	28744293	XL	2	conducted the experiments and analyzed data	conducted the experiments and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5504165	28744293	YP	2	designed the experiments|conducted the experiments and analyzed data|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5504165	28744293	YP	2	designed the experiments|conducted the experiments and analyzed data|wrote the manuscript	conducted the experiments and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5504165	28744293	YP	2	designed the experiments|conducted the experiments and analyzed data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4309828	25630823	B Rourke	2	have contributed substantially to the design of the study, the data collection and analysis, and/or the preparation of the manuscript	have contributed substantially to the design of the study, the data collection and analysis, and/or the preparation of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
4309828	25630823	Shirin Heidari	2	have contributed substantially to the design of the study, the data collection and analysis, and/or the preparation of the manuscript	have contributed substantially to the design of the study, the data collection and analysis, and/or the preparation of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
4972562	27333026	AV	2	did the laboratory work and dna extraction|commented on the drafts of the paper	did the laboratory work and dna extraction	Performed the experiments	Investigation	YES
4972562	27333026	AV	2	did the laboratory work and dna extraction|commented on the drafts of the paper	commented on the drafts of the paper	Wrote the paper	Writing - Original Draft	YES
4972562	27333026	CR	2	did the laboratory work and dna extraction|interpreted the data, prepared the figures, and did the literature search|commented on the drafts of the paper	did the laboratory work and dna extraction	Performed the experiments	Investigation	YES
4972562	27333026	CR	2	did the laboratory work and dna extraction|interpreted the data, prepared the figures, and did the literature search|commented on the drafts of the paper	interpreted the data, prepared the figures, and did the literature search	Analyzed the data	Formal analysis|Visualization	YES
4972562	27333026	CR	2	did the laboratory work and dna extraction|interpreted the data, prepared the figures, and did the literature search|commented on the drafts of the paper	commented on the drafts of the paper	Wrote the paper	Writing - Original Draft	YES
4972562	27333026	ECB	2	designed the study|interpreted the data, prepared the figures, and did the literature search|wrote the report	designed the study	Conceived and designed the experiments	Methodology	YES
4972562	27333026	ECB	2	designed the study|interpreted the data, prepared the figures, and did the literature search|wrote the report	interpreted the data, prepared the figures, and did the literature search	Analyzed the data	Formal analysis|Visualization	YES
4972562	27333026	ECB	2	designed the study|interpreted the data, prepared the figures, and did the literature search|wrote the report	wrote the report	Wrote the paper	Writing - Original Draft	YES
4972562	27333026	GVB	2	collected epidemiological data|interpreted the data, prepared the figures, and did the literature search|wrote the report	collected epidemiological data	Performed the experiments	Investigation	YES
4972562	27333026	GVB	2	collected epidemiological data|interpreted the data, prepared the figures, and did the literature search|wrote the report	interpreted the data, prepared the figures, and did the literature search	Analyzed the data	Formal analysis|Visualization	YES
4972562	27333026	GVB	2	collected epidemiological data|interpreted the data, prepared the figures, and did the literature search|wrote the report	wrote the report	Wrote the paper	Writing - Original Draft	YES
4972562	27333026	PMK	2	collected epidemiological data|interpreted the data, prepared the figures, and did the literature search|commented on the drafts of the paper	collected epidemiological data	Performed the experiments	Investigation	YES
4972562	27333026	PMK	2	collected epidemiological data|interpreted the data, prepared the figures, and did the literature search|commented on the drafts of the paper	interpreted the data, prepared the figures, and did the literature search	Analyzed the data	Formal analysis|Visualization	YES
4972562	27333026	PMK	2	collected epidemiological data|interpreted the data, prepared the figures, and did the literature search|commented on the drafts of the paper	commented on the drafts of the paper	Wrote the paper	Writing - Original Draft	YES
4972562	27333026	RH	2	did the laboratory work and dna extraction|commented on the drafts of the paper	did the laboratory work and dna extraction	Performed the experiments	Investigation	YES
4972562	27333026	RH	2	did the laboratory work and dna extraction|commented on the drafts of the paper	commented on the drafts of the paper	Wrote the paper	Writing - Original Draft	YES
4972562	27333026	VD	2	collected epidemiological data|interpreted the data, prepared the figures, and did the literature search|wrote the report	collected epidemiological data	Performed the experiments	Investigation	YES
4972562	27333026	VD	2	collected epidemiological data|interpreted the data, prepared the figures, and did the literature search|wrote the report	interpreted the data, prepared the figures, and did the literature search	Analyzed the data	Formal analysis|Visualization	YES
4972562	27333026	VD	2	collected epidemiological data|interpreted the data, prepared the figures, and did the literature search|wrote the report	wrote the report	Wrote the paper	Writing - Original Draft	YES
521069	15357875	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
521069	15357875	ID	2	is used to identify steps where the problems, if any, are found	is used to identify steps where the problems, if any, are found	Performed the experiments	Investigation	YES
521069	15357875	IT	2	developed the heuristic and carried out analysis and implementation	developed the heuristic and carried out analysis and implementation	Performed the experiments	Investigation	YES
521069	15357875	MD	2	provided advice and checked our work with an alternative technique	provided advice and checked our work with an alternative technique	-	-	NO
521069	15357875	MF	2	developed the heuristic and carried out analysis and implementation	developed the heuristic and carried out analysis and implementation	Performed the experiments	Investigation	YES
521069	15357875	MS	2	brought this problem to our attention and provided test data	brought this problem to our attention and provided test data	Contributed reagents/materials/analysis tools	Resources	YES
521069	15357875	PCR	2	round at 96 level 2|round at 96 level 3	round at 96 level 2	-	-	NO
521069	15357875	PCR	2	round at 96 level 2|round at 96 level 3	round at 96 level 3	-	-	NO
4523163	26257910	Christian F. Camm	7	editing	editing	Wrote the paper	Writing - Review & Editing	YES
4523163	26257910	Eric Edison	7	wrote first draft	wrote first draft	Wrote the paper	Writing - Original Draft	YES
4523163	26257910	Riaz Agha	7	conception and editing	conception and editing	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
4483220	26120348	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4483220	26120348	CDCs	PLoS52	for their efforts and assistance with this study	for their efforts and assistance with this study	-	-	NO
4483220	26120348	CL	PLoS52	conducted research at sites	conducted research at sites	Performed the experiments	Investigation	YES
4483220	26120348	DS	PLoS52	performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
4483220	26120348	GS	PLoS52	conducted research at sites	conducted research at sites	Performed the experiments	Investigation	YES
4483220	26120348	JL	PLoS52	wrote the paper|conceived and designed the study|performed the statistical analysis|performed the experiments|carried out staff training and quality management|conducted research at sites	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4483220	26120348	JL	PLoS52	wrote the paper|conceived and designed the study|performed the statistical analysis|performed the experiments|carried out staff training and quality management|conducted research at sites	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4483220	26120348	JL	PLoS52	wrote the paper|conceived and designed the study|performed the statistical analysis|performed the experiments|carried out staff training and quality management|conducted research at sites	performed the statistical analysis	Analyzed the data	Formal analysis	YES
4483220	26120348	JL	PLoS52	wrote the paper|conceived and designed the study|performed the statistical analysis|performed the experiments|carried out staff training and quality management|conducted research at sites	performed the experiments	Performed the experiments	Investigation	YES
4483220	26120348	JL	PLoS52	wrote the paper|conceived and designed the study|performed the statistical analysis|performed the experiments|carried out staff training and quality management|conducted research at sites	carried out staff training and quality management	Performed the experiments	Investigation	YES
4483220	26120348	JL	PLoS52	wrote the paper|conceived and designed the study|performed the statistical analysis|performed the experiments|carried out staff training and quality management|conducted research at sites	conducted research at sites	Performed the experiments	Investigation	YES
4483220	26120348	QZ	PLoS52	performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
4483220	26120348	ST	PLoS52	conducted research at sites	conducted research at sites	Performed the experiments	Investigation	YES
4483220	26120348	WY	PLoS52	performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
4483220	26120348	XX	PLoS52	conducted research at sites	conducted research at sites	Performed the experiments	Investigation	YES
4483220	26120348	YW	PLoS52	performed the experiments|carried out staff training and quality management	performed the experiments	Performed the experiments	Investigation	YES
4483220	26120348	YW	PLoS52	performed the experiments|carried out staff training and quality management	carried out staff training and quality management	Performed the experiments	Investigation	YES
4483220	26120348	ZW	PLoS52	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403990	25893500	EL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4403990	25893500	HKK	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403990	25893500	HKK	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4403990	25893500	HKK	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403990	25893500	HKK	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403990	25893500	IUNS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403990	25893500	IUNS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4403990	25893500	IUNS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403990	25893500	IUNS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403990	25893500	IUNS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403990	25893500	JKAK	PLoS5	Supervision and revision of the manuscript	Supervision and revision of the manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
4403990	25893500	JLNN	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4403990	25893500	KN	PLoS5	Supervision and revision of the manuscript	Supervision and revision of the manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
4403990	25893500	LGL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403990	25893500	MN	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4403990	25893500	YN	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4523164	26257906	CB	7	Concept, Design, Critical Revision, final Approval	Concept, Design, Critical Revision, final Approval	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
4523164	26257906	CfC	7	Critical Revision, final Approval	Critical Revision, final Approval	Wrote the paper	Writing - Review & Editing	YES
4523164	26257906	EE	7	Writing, Critical Revision, final Approval	Writing, Critical Revision, final Approval	Wrote the paper	Writing - Review & Editing	YES
4523164	26257906	LC	7	Design, final Approval	Design, final Approval	Conceived and designed the experiments	-	YES
4523164	26257906	PG	7	Design, final Approval	Design, final Approval	Conceived and designed the experiments	-	YES
4523164	26257906	RAA	7	Concept, Design, Critical Revision, final Approval	Concept, Design, Critical Revision, final Approval	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5504168	28744289	DT	PLoS52	conducted the statistical analysis	conducted the statistical analysis	Analyzed the data	Formal analysis	YES
5504168	28744289	GD	PLoS52	designed the experiments and supervised the work	designed the experiments and supervised the work	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Supervision	YES
5504168	28744289	GL	PLoS52	supervised the work and finalized the manuscript	supervised the work and finalized the manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
5504168	28744289	JW	PLoS52	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5504168	28744289	JZ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5504168	28744289	QY	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5504168	28744289	XY	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5504168	28744289	YT	PLoS52	performed the experiments and data analysis	performed the experiments and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5504168	28744289	YaZ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5504168	28744289	YiW	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5504168	28744289	YoZ	PLoS52	conducted the statistical analysis and paper drafting	conducted the statistical analysis and paper drafting	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5504168	28744289	YuW	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
4312354	25636349	BT	2	performed the statistical analysis, interpreted the results and wrote the first draft of the manuscript	performed the statistical analysis, interpreted the results and wrote the first draft of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4312354	25636349	DKE	2	performed the statistical analysis, interpreted the results and wrote the first draft of the manuscript	performed the statistical analysis, interpreted the results and wrote the first draft of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4312354	25636349	SPE	2	contributed to critical reading and the final version of the manuscript	contributed to critical reading and the final version of the manuscript	-	-	NO
6408865	30899516	All authors	2	contributed to the drafting and review of the manuscript	contributed to the drafting and review of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6408865	30899516	CN	2	were involved in development of study concept, analysis, and interpretation of the data	were involved in development of study concept, analysis, and interpretation of the data	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
6408865	30899516	JY	2	were involved in development of study concept, analysis, and interpretation of the data	were involved in development of study concept, analysis, and interpretation of the data	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
6408865	30899516	PMG	2	were involved in development of study concept, analysis, and interpretation of the data	were involved in development of study concept, analysis, and interpretation of the data	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
6408865	30899516	SB	2	collected the animal data	collected the animal data	Performed the experiments	Investigation	YES
5408752	28135077	J.R.C.	2	contributed equally	contributed equally	-	-	NO
5408752	28135077	L.M.R.	2	contributed equally	contributed equally	-	-	NO
521070	15369602	AV	2	conceived the study, and participated in its design and coordination|finalised the manuscript	conceived the study, and participated in its design and coordination	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
521070	15369602	AV	2	conceived the study, and participated in its design and coordination|finalised the manuscript	finalised the manuscript	Wrote the paper	Writing - Review & Editing	YES
521070	15369602	BA	2	carried out most of the molecular studies	carried out most of the molecular studies	Performed the experiments	Investigation	YES
521070	15369602	FP	2	carried out most of the molecular studies|drafted the manuscript	carried out most of the molecular studies	Performed the experiments	Investigation	YES
521070	15369602	FP	2	carried out most of the molecular studies|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
521070	15369602	FV	2	were involved in the characterization of the panel	were involved in the characterization of the panel	Performed the experiments	Investigation	YES
521070	15369602	KF	2	were involved in the characterization of the panel	were involved in the characterization of the panel	Performed the experiments	Investigation	YES
521070	15369602	MD	2	conceived the study, and participated in its design and coordination	conceived the study, and participated in its design and coordination	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
521070	15369602	MG	2	were involved in the gga5 study	were involved in the gga5 study	-	-	NO
521070	15369602	MM	2	made the rh panel	made the rh panel	-	-	NO
521070	15369602	RC	2	were involved in the gga5 study	were involved in the gga5 study	-	-	NO
521070	15369602	SB	2	were involved in the characterization of the panel	were involved in the characterization of the panel	Performed the experiments	Investigation	YES
521070	15369602	SL	2	were involved in the characterization of the panel	were involved in the characterization of the panel	Performed the experiments	Investigation	YES
5006577	27349457	ES	2	wrote parts of and edited the manuscript	wrote parts of and edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5006577	27349457	FQ	2	conducted experiments and analyzed the data	conducted experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5006577	27349457	GEC	2	designed the study|conducted experiments, analyzed the data, and wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5006577	27349457	GEC	2	designed the study|conducted experiments, analyzed the data, and wrote the manuscript	conducted experiments, analyzed the data, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5006577	27349457	GPD	2	designed the study|conducted experiments, analyzed the data, and wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5006577	27349457	GPD	2	designed the study|conducted experiments, analyzed the data, and wrote the manuscript	conducted experiments, analyzed the data, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5006577	27349457	HPL	2	designed the study|conducted experiments, analyzed the data, and wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5006577	27349457	HPL	2	designed the study|conducted experiments, analyzed the data, and wrote the manuscript	conducted experiments, analyzed the data, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5006577	27349457	JAC	2	designed the study|wrote parts of and edited the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5006577	27349457	JAC	2	designed the study|wrote parts of and edited the manuscript	wrote parts of and edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5006577	27349457	JW	2	conducted experiments and analyzed the data	conducted experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4403991	25894755	BE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403991	25894755	BE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4403991	25894755	BE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4403991	25894755	CV	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4403991	25894755	CV	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4403991	25894755	IRM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4403991	25894755	IRM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403991	25894755	JAB	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403991	25894755	JAB	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403991	25894755	JG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403991	25894755	JG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403991	25894755	JG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403991	25894755	JM	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4403991	25894755	JM	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4403991	25894755	JV	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4403991	25894755	JV	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4403991	25894755	JV	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4323407	25669423	CVC	2	helped oversee study procedures and data collection	helped oversee study procedures and data collection	Performed the experiments	Investigation|Supervision	YES
4323407	25669423	DA	2	assisted with statistical analyses and interpretation of results	assisted with statistical analyses and interpretation of results	Analyzed the data	Formal analysis	YES
4323407	25669423	DG	2	was responsible for data collection|performed statistical analyses|contributed to study design, developed hypotheses and interpreted results	was responsible for data collection	Performed the experiments	Investigation	YES
4323407	25669423	DG	2	was responsible for data collection|performed statistical analyses|contributed to study design, developed hypotheses and interpreted results	performed statistical analyses	Analyzed the data	Formal analysis	YES
4323407	25669423	DG	2	was responsible for data collection|performed statistical analyses|contributed to study design, developed hypotheses and interpreted results	contributed to study design, developed hypotheses and interpreted results	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
4323407	25669423	EVP	2	wrote the manuscript|performed statistical analyses|contributed to study design, developed hypotheses and interpreted results	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4323407	25669423	EVP	2	wrote the manuscript|performed statistical analyses|contributed to study design, developed hypotheses and interpreted results	performed statistical analyses	Analyzed the data	Formal analysis	YES
4323407	25669423	EVP	2	wrote the manuscript|performed statistical analyses|contributed to study design, developed hypotheses and interpreted results	contributed to study design, developed hypotheses and interpreted results	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
4323407	25669423	JLG	2	helped oversee study procedures and data collection	helped oversee study procedures and data collection	Performed the experiments	Investigation|Supervision	YES
4323407	25669423	KT	2	helped oversee study procedures and data collection	helped oversee study procedures and data collection	Performed the experiments	Investigation|Supervision	YES
4323407	25669423	SAS	2	contributed to study design, developed hypotheses and interpreted results	contributed to study design, developed hypotheses and interpreted results	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
4323407	25669423	TLP	2	contributed to study design, developed hypotheses and interpreted results	contributed to study design, developed hypotheses and interpreted results	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
5504171	28744292	All authors	PLoS52	contributed critically to the drafts and gave final approval for publication	contributed critically to the drafts and gave final approval for publication	Wrote the paper	Writing - Original Draft	YES
5504171	28744292	BGG	PLoS52	collected the data	collected the data	Performed the experiments	Investigation	YES
5504171	28744292	GGI	PLoS52	conceived the ideas and designed methodology|collected the data	conceived the ideas and designed methodology	Conceived and designed the experiments|Performed the experiments	Conceptualization|Methodology	YES
5504171	28744292	GGI	PLoS52	conceived the ideas and designed methodology|collected the data	collected the data	Performed the experiments	Investigation	YES
5504171	28744292	IA	PLoS52	conceived the ideas and designed methodology|collected the data	conceived the ideas and designed methodology	Conceived and designed the experiments|Performed the experiments	Conceptualization|Methodology	YES
5504171	28744292	IA	PLoS52	conceived the ideas and designed methodology|collected the data	collected the data	Performed the experiments	Investigation	YES
5504171	28744292	IC	PLoS52	conceived the ideas and designed methodology	conceived the ideas and designed methodology	Conceived and designed the experiments|Performed the experiments	Conceptualization|Methodology	YES
5504171	28744292	LFU	PLoS52	conceived the ideas and designed methodology|collected the data|analyzed the data|led the writing of the manuscript	conceived the ideas and designed methodology	Conceived and designed the experiments|Performed the experiments	Conceptualization|Methodology	YES
5504171	28744292	LFU	PLoS52	conceived the ideas and designed methodology|collected the data|analyzed the data|led the writing of the manuscript	collected the data	Performed the experiments	Investigation	YES
5504171	28744292	LFU	PLoS52	conceived the ideas and designed methodology|collected the data|analyzed the data|led the writing of the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5504171	28744292	LFU	PLoS52	conceived the ideas and designed methodology|collected the data|analyzed the data|led the writing of the manuscript	led the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5504171	28744292	PF	PLoS52	conceived the ideas and designed methodology	conceived the ideas and designed methodology	Conceived and designed the experiments|Performed the experiments	Conceptualization|Methodology	YES
5504171	28744292	SR	PLoS52	conceived the ideas and designed methodology|analyzed the data	conceived the ideas and designed methodology	Conceived and designed the experiments|Performed the experiments	Conceptualization|Methodology	YES
5504171	28744292	SR	PLoS52	conceived the ideas and designed methodology|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
4501274	26175795	AM	2	drafted the manuscript and reviewed the literature	drafted the manuscript and reviewed the literature	Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
4501274	26175795	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4501274	26175795	CSF	2	blood sampling, and supervised the drafting of the manuscript	blood sampling, and supervised the drafting of the manuscript	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Original Draft	YES
4501274	26175795	EB	2	drafted the manuscript and reviewed the literature	drafted the manuscript and reviewed the literature	Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
4501274	26175795	HZ	2	carried out csf analyses	carried out csf analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4501274	26175795	LK	2	carried out clinical practice	carried out clinical practice	Performed the experiments	Investigation	YES
4501274	26175795	SM	2	carried out clinical practice	carried out clinical practice	Performed the experiments	Investigation	YES
521075	15380029	JWS	2	performed phylogenetic analysis|contributed editorial revisions	performed phylogenetic analysis	Performed the experiments	Investigation	YES
521075	15380029	JWS	2	performed phylogenetic analysis|contributed editorial revisions	contributed editorial revisions	Wrote the paper	Writing - Review & Editing	YES
521075	15380029	ZG	2	performed phylogenetic analysis	performed phylogenetic analysis	Performed the experiments	Investigation	YES
4523168	26257908	CFC	7	Concept, Critical Revision, Final Approval	Concept, Critical Revision, Final Approval	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
4523168	26257908	PJT	7	Writing, Critical Revision, Final Approval	Writing, Critical Revision, Final Approval	Wrote the paper	Writing - Review & Editing	YES
5006601	27381476	EMA	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5006601	27381476	EMA	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5006601	27381476	EMA	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5006601	27381476	EMA	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5006601	27381476	JAO	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5006601	27381476	JAO	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5006601	27381476	JAO	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5006601	27381476	JAO	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5006601	27381476	LAK	PLoS52	performed the experiments|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5006601	27381476	LAK	PLoS52	performed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5006601	27381476	MGS	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5006601	27381476	MMS	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5006601	27381476	RCT	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
4403992	25893403	AM	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403992	25893403	AM	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403992	25893403	ET	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403992	25893403	ET	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4403992	25893403	ET	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403992	25893403	ET	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403992	25893403	FA	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403992	25893403	FA	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4403992	25893403	FA	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403992	25893403	FD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403992	25893403	FD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403992	25893403	FD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403992	25893403	FD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403992	25893403	GSD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403992	25893403	GSD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4403992	25893403	GSD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403992	25893403	GSD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403992	25893403	HD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403992	25893403	HD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4403992	25893403	HD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4403992	25893403	HD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403992	25893403	KP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403992	25893403	KP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403992	25893403	PO	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403992	25893403	PO	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4403992	25893403	PO	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403992	25893403	SPY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403992	25893403	SPY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4403992	25893403	SPY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4403992	25893403	ST	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403992	25893403	ST	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403992	25893403	VY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403992	25893403	VY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4403992	25893403	VY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403992	25893403	VY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403992	25893403	YGP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403992	25893403	YGP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4526419	26251665	All authors	2	read and approved the manuscript	read and approved the manuscript	-	-	NO
4526419	26251665	GM	2	designed and conducted the study|edited the manuscript and drafted revisions	designed and conducted the study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4526419	26251665	GM	2	designed and conducted the study|edited the manuscript and drafted revisions	edited the manuscript and drafted revisions	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4526419	26251665	JD	2	designed and conducted the study|edited the manuscript and drafted revisions	designed and conducted the study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4526419	26251665	JD	2	designed and conducted the study|edited the manuscript and drafted revisions	edited the manuscript and drafted revisions	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4526419	26251665	NL	2	designed and conducted the study|edited the manuscript and drafted revisions	designed and conducted the study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4526419	26251665	NL	2	designed and conducted the study|edited the manuscript and drafted revisions	edited the manuscript and drafted revisions	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4526419	26251665	ZA	2	conducted all statistical analyses, interpreted the findings and drafted the manuscript	conducted all statistical analyses, interpreted the findings and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4327894	25680919	AS	2	contributed to the study concept and design	contributed to the study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4327894	25680919	All authors	2	were responsible for the critical revision and intellectual content of the manuscript and approved the final version	were responsible for the critical revision and intellectual content of the manuscript and approved the final version	Wrote the paper	Writing - Review & Editing	YES
4327894	25680919	BW	2	contributed to the study concept and design	contributed to the study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4327894	25680919	DS	2	contributed to the study concept and design|were responsible for the acquisition of data	contributed to the study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4327894	25680919	DS	2	contributed to the study concept and design|were responsible for the acquisition of data	were responsible for the acquisition of data	Performed the experiments	Investigation	YES
4327894	25680919	HM	2	contributed to the study concept and design|were responsible for the acquisition of data	contributed to the study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4327894	25680919	HM	2	contributed to the study concept and design|were responsible for the acquisition of data	were responsible for the acquisition of data	Performed the experiments	Investigation	YES
4327894	25680919	JH	2	contributed to the study concept and design|were responsible for the acquisition of data	contributed to the study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4327894	25680919	JH	2	contributed to the study concept and design|were responsible for the acquisition of data	were responsible for the acquisition of data	Performed the experiments	Investigation	YES
4327894	25680919	JW	2	contributed to the study concept and design	contributed to the study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4327894	25680919	KP	2	contributed to the study concept and design|were responsible for the acquisition of data|were responsible for the analysis and interpretation of the data and drafting of the manuscript	contributed to the study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4327894	25680919	KP	2	contributed to the study concept and design|were responsible for the acquisition of data|were responsible for the analysis and interpretation of the data and drafting of the manuscript	were responsible for the acquisition of data	Performed the experiments	Investigation	YES
4327894	25680919	KP	2	contributed to the study concept and design|were responsible for the acquisition of data|were responsible for the analysis and interpretation of the data and drafting of the manuscript	were responsible for the analysis and interpretation of the data and drafting of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4327894	25680919	LB	2	contributed to the study concept and design	contributed to the study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4327894	25680919	MGL	2	contributed to the study concept and design|were responsible for the acquisition of data|were responsible for the analysis and interpretation of the data and drafting of the manuscript	contributed to the study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4327894	25680919	MGL	2	contributed to the study concept and design|were responsible for the acquisition of data|were responsible for the analysis and interpretation of the data and drafting of the manuscript	were responsible for the acquisition of data	Performed the experiments	Investigation	YES
4327894	25680919	MGL	2	contributed to the study concept and design|were responsible for the acquisition of data|were responsible for the analysis and interpretation of the data and drafting of the manuscript	were responsible for the analysis and interpretation of the data and drafting of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4327894	25680919	RF	2	contributed to the study concept and design|were responsible for the acquisition of data	contributed to the study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4327894	25680919	RF	2	contributed to the study concept and design|were responsible for the acquisition of data	were responsible for the acquisition of data	Performed the experiments	Investigation	YES
4327894	25680919	SW	2	contributed to the study concept and design|were responsible for the acquisition of data	contributed to the study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4327894	25680919	SW	2	contributed to the study concept and design|were responsible for the acquisition of data	were responsible for the acquisition of data	Performed the experiments	Investigation	YES
5504172	28744294	CW	2	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5504172	28744294	FL	2	given the advice for data analyzing	given the advice for data analyzing	Analyzed the data	Formal analysis	YES
5504172	28744294	JZ	2	performed pcr validation experiments	performed pcr validation experiments	Performed the experiments	Investigation|Validation	YES
5504172	28744294	QX	2	analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5504172	28744294	SZ	2	given the advice for data analyzing	given the advice for data analyzing	Analyzed the data	Formal analysis	YES
5504172	28744294	XW	2	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5504172	28744294	YH	2	given the advice for data analyzing	given the advice for data analyzing	Analyzed the data	Formal analysis	YES
5504172	28744294	YT	2	provided bacterial artificial chromosome libraries	provided bacterial artificial chromosome libraries	-	-	NO
6412143	30906562	A.J.F.	2	participated in data analysis	participated in data analysis	Analyzed the data	Formal analysis	YES
6412143	30906562	A.L.	2	performed lumbar puncture and monitored patients	performed lumbar puncture and monitored patients	Performed the experiments	Investigation|Supervision	YES
6412143	30906562	B.W.	2	treated, consented, monitored, and tested patients	treated, consented, monitored, and tested patients	Performed the experiments	Investigation|Supervision	YES
6412143	30906562	C.M.	2	designed the study and wrote the manuscript	designed the study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
6412143	30906562	E.E.M.	2	performed lumbar puncture and monitored patients	performed lumbar puncture and monitored patients	Performed the experiments	Investigation|Supervision	YES
6412143	30906562	F.P.	2	was the principal investigator	was the principal investigator	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
6412143	30906562	H.H.H.	2	were the outreach coordinators	were the outreach coordinators	-	Project administration	YES
6412143	30906562	J.A.	2	were the outreach coordinators|performed all statistics	were the outreach coordinators	-	Project administration	YES
6412143	30906562	J.A.	2	were the outreach coordinators|performed all statistics	performed all statistics	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6412143	30906562	M.L.H.	2	processed the bio-fluid samples	processed the bio-fluid samples	Analyzed the data	Data curation	YES
6412143	30906562	M.P.	2	performed data management	performed data management	Analyzed the data	Data curation	YES
6412143	30906562	N.J.S.	2	performed lumbar puncture and monitored patients	performed lumbar puncture and monitored patients	Performed the experiments	Investigation|Supervision	YES
6412143	30906562	N.Y.	2	performed lumbar puncture and monitored patients	performed lumbar puncture and monitored patients	Performed the experiments	Investigation|Supervision	YES
6412143	30906562	S.L.S.	2	oversaw the pk studies	oversaw the pk studies	-	Supervision	YES
6412143	30906562	S.M.	2	performed data management	performed data management	Analyzed the data	Data curation	YES
6412143	30906562	X.L.	2	participated in data analysis	participated in data analysis	Analyzed the data	Formal analysis	YES
6412143	30906562	Y.T.Y.	2	performed lumbar puncture and monitored patients	performed lumbar puncture and monitored patients	Performed the experiments	Investigation|Supervision	YES
4403993	25894745	DKD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403993	25894745	DKD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4403993	25894745	DKD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403993	25894745	DKD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403993	25894745	DKD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403993	25894745	KR	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4403993	25894745	PAP	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4403993	25894745	PAP	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403993	25894745	SCW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403993	25894745	SCW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4403993	25894745	SCW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4536604	26279667	AK	2	participated in data entry and data collection	participated in data entry and data collection	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
4536604	26279667	AS	2	performed the statistical analysis and drafted the manuscript	performed the statistical analysis and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4536604	26279667	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4536604	26279667	BM	2	participated in data analysis and drafting the manuscript	participated in data analysis and drafting the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4536604	26279667	DS	2	carried out the data analysis, figure formatting and helped to draft the manuscript	carried out the data analysis, figure formatting and helped to draft the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Visualization|Writing - Original Draft	YES
4536604	26279667	MT	2	participated in study design, coordination and finalizing the manuscript	participated in study design, coordination and finalizing the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Review & Editing	YES
4536604	26279667	RP	2	participated in finalizing the manuscript	participated in finalizing the manuscript	Wrote the paper	Writing - Review & Editing	YES
4539162	26288729	All authors	2	were involved in drafting the article or revising it critically for important intellectual content, and all authors approved the final version for publication	were involved in drafting the article or revising it critically for important intellectual content, and all authors approved the final version for publication	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4539162	26288729	OO	2	performed the analysis and drafted the manuscript	performed the analysis and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
521486	15377392	AB	2	oversaw the database design and development activity, and the latter led the write-up	oversaw the database design and development activity, and the latter led the write-up	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Software|Supervision	YES
521486	15377392	AH	2	conducted or led experimental activities that generated the data in the database, and contributed to feedback on the model	conducted or led experimental activities that generated the data in the database, and contributed to feedback on the model	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Software	YES
521486	15377392	AJPB	2	conducted or led experimental activities that generated the data in the database, and contributed to feedback on the model	conducted or led experimental activities that generated the data in the database, and contributed to feedback on the model	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Software	YES
521486	15377392	AW	2	conducted or led experimental activities that generated the data in the database, and contributed to feedback on the model	conducted or led experimental activities that generated the data in the database, and contributed to feedback on the model	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Software	YES
521486	15377392	CE	2	conducted or led experimental activities that generated the data in the database, and contributed to feedback on the model	conducted or led experimental activities that generated the data in the database, and contributed to feedback on the model	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Software	YES
521486	15377392	CFT	2	contributed to the development of earlier prototypes	contributed to the development of earlier prototypes	-	-	NO
521486	15377392	CG	2	implemented the software	implemented the software	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
521486	15377392	CK	2	conducted or led experimental activities that generated the data in the database, and contributed to feedback on the model	conducted or led experimental activities that generated the data in the database, and contributed to feedback on the model	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Software	YES
521486	15377392	DS	2	conducted or led experimental activities that generated the data in the database, and contributed to feedback on the model	conducted or led experimental activities that generated the data in the database, and contributed to feedback on the model	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Software	YES
521486	15377392	JH	2	conducted or led experimental activities that generated the data in the database, and contributed to feedback on the model	conducted or led experimental activities that generated the data in the database, and contributed to feedback on the model	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Software	YES
521486	15377392	KC	2	conducted or led experimental activities that generated the data in the database, and contributed to feedback on the model	conducted or led experimental activities that generated the data in the database, and contributed to feedback on the model	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Software	YES
521486	15377392	KG	2	implemented the software	implemented the software	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
521486	15377392	KSL	2	conducted or led experimental activities that generated the data in the database, and contributed to feedback on the model	conducted or led experimental activities that generated the data in the database, and contributed to feedback on the model	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Software	YES
521486	15377392	LH	2	conducted or led experimental activities that generated the data in the database, and contributed to feedback on the model	conducted or led experimental activities that generated the data in the database, and contributed to feedback on the model	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Software	YES
521486	15377392	MM	2	conducted or led experimental activities that generated the data in the database, and contributed to feedback on the model	conducted or led experimental activities that generated the data in the database, and contributed to feedback on the model	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Software	YES
521486	15377392	NM	2	contributed to the development of earlier prototypes	contributed to the development of earlier prototypes	-	-	NO
521486	15377392	NWP	2	oversaw the database design and development activity, and the latter led the write-up	oversaw the database design and development activity, and the latter led the write-up	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Software|Supervision	YES
521486	15377392	PG	2	conducted or led experimental activities that generated the data in the database, and contributed to feedback on the model	conducted or led experimental activities that generated the data in the database, and contributed to feedback on the model	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Software	YES
521486	15377392	SH	2	conducted or led experimental activities that generated the data in the database, and contributed to feedback on the model	conducted or led experimental activities that generated the data in the database, and contributed to feedback on the model	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Software	YES
521486	15377392	SJ	2	contributed to the development of earlier prototypes	contributed to the development of earlier prototypes	-	-	NO
521486	15377392	SJG	2	conducted or led experimental activities that generated the data in the database, and contributed to feedback on the model	conducted or led experimental activities that generated the data in the database, and contributed to feedback on the model	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Software	YES
521486	15377392	SJH	2	oversaw the database design and development activity, and the latter led the write-up	oversaw the database design and development activity, and the latter led the write-up	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Software|Supervision	YES
521486	15377392	SJO	2	oversaw the database design and development activity, and the latter led the write-up	oversaw the database design and development activity, and the latter led the write-up	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Software|Supervision	YES
521486	15377392	TM	2	coordinated the data capture activity	coordinated the data capture activity	-	Project administration	YES
521486	15377392	ZY	2	conducted or led experimental activities that generated the data in the database, and contributed to feedback on the model	conducted or led experimental activities that generated the data in the database, and contributed to feedback on the model	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Software	YES
4331401	25690530	All authors	2	have significantly contributed to this study|have seen and approved the last version of the manuscript|had an opportunity to contribute to the interpretation of the results	have significantly contributed to this study	-	-	NO
4331401	25690530	All authors	2	have significantly contributed to this study|have seen and approved the last version of the manuscript|had an opportunity to contribute to the interpretation of the results	have seen and approved the last version of the manuscript	-	-	NO
4331401	25690530	All authors	2	have significantly contributed to this study|have seen and approved the last version of the manuscript|had an opportunity to contribute to the interpretation of the results	had an opportunity to contribute to the interpretation of the results	Analyzed the data	Formal analysis	YES
4331401	25690530	AvdV	2	were responsible for the conception and design of this study|wrote the first draft of the manuscript, and all other authors contributed to further drafts and approved the final manuscript	were responsible for the conception and design of this study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4331401	25690530	AvdV	2	were responsible for the conception and design of this study|wrote the first draft of the manuscript, and all other authors contributed to further drafts and approved the final manuscript	wrote the first draft of the manuscript, and all other authors contributed to further drafts and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4331401	25690530	BA	2	were responsible for the conception and design of this study|collected and assembled the data in indonesia	were responsible for the conception and design of this study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4331401	25690530	BA	2	were responsible for the conception and design of this study|collected and assembled the data in indonesia	collected and assembled the data in indonesia	Performed the experiments	Investigation	YES
4331401	25690530	HM	2	were responsible for the conception and design of this study|wrote the first draft of the manuscript, and all other authors contributed to further drafts and approved the final manuscript	were responsible for the conception and design of this study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4331401	25690530	HM	2	were responsible for the conception and design of this study|wrote the first draft of the manuscript, and all other authors contributed to further drafts and approved the final manuscript	wrote the first draft of the manuscript, and all other authors contributed to further drafts and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4331401	25690530	IM	2	collected and assembled the data in indonesia	collected and assembled the data in indonesia	Performed the experiments	Investigation	YES
4331401	25690530	LC	2	collected and assembled the data in indonesia	collected and assembled the data in indonesia	Performed the experiments	Investigation	YES
4331401	25690530	MI	2	collected and assembled the data in indonesia	collected and assembled the data in indonesia	Performed the experiments	Investigation	YES
4331401	25690530	RW	2	were responsible for the conception and design of this study|collected and assembled the data in indonesia|under the	were responsible for the conception and design of this study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4331401	25690530	RW	2	were responsible for the conception and design of this study|collected and assembled the data in indonesia|under the	collected and assembled the data in indonesia	Performed the experiments	Investigation	YES
4331401	25690530	RW	2	were responsible for the conception and design of this study|collected and assembled the data in indonesia|under the	under the	-	-	NO
4331401	25690530	RvC	2	were responsible for the conception and design of this study|supervised the and under the|wrote the first draft of the manuscript, and all other authors contributed to further drafts and approved the final manuscript	were responsible for the conception and design of this study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4331401	25690530	RvC	2	were responsible for the conception and design of this study|supervised the and under the|wrote the first draft of the manuscript, and all other authors contributed to further drafts and approved the final manuscript	supervised the and under the	-	Supervision	YES
4331401	25690530	RvC	2	were responsible for the conception and design of this study|supervised the and under the|wrote the first draft of the manuscript, and all other authors contributed to further drafts and approved the final manuscript	wrote the first draft of the manuscript, and all other authors contributed to further drafts and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5504180	28744298	GG	2	conceived the idea of writing the paper|wrote the manuscript	conceived the idea of writing the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5504180	28744298	GG	2	conceived the idea of writing the paper|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5504180	28744298	JH	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5504180	28744298	SE	2	conceived the idea of writing the paper|wrote the manuscript	conceived the idea of writing the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5504180	28744298	SE	2	conceived the idea of writing the paper|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5504180	28744298	SL	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4403994	25894558	JSB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the software used to collect data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403994	25894558	JSB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the software used to collect data	Performed the experiments	Performed the experiments	Investigation	YES
4403994	25894558	JSB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the software used to collect data	Analyzed the data	Analyzed the data	Formal analysis	YES
4403994	25894558	JSB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the software used to collect data	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403994	25894558	JSB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the software used to collect data	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403994	25894558	JSB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the software used to collect data	Designed the software used to collect data	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
4403994	25894558	MEH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Designed the software used to collect data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403994	25894558	MEH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Designed the software used to collect data	Performed the experiments	Performed the experiments	Investigation	YES
4403994	25894558	MEH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Designed the software used to collect data	Analyzed the data	Analyzed the data	Formal analysis	YES
4403994	25894558	MEH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Designed the software used to collect data	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403994	25894558	MEH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Designed the software used to collect data	Designed the software used to collect data	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
4403994	25894558	RCF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the software used to collect data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403994	25894558	RCF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the software used to collect data	Performed the experiments	Performed the experiments	Investigation	YES
4403994	25894558	RCF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the software used to collect data	Analyzed the data	Analyzed the data	Formal analysis	YES
4403994	25894558	RCF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the software used to collect data	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403994	25894558	RCF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the software used to collect data	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403994	25894558	RCF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the software used to collect data	Designed the software used to collect data	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
4403994	25894558	TL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4403994	25894558	TL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403994	25894558	TL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5006644	27381477	G.I.	2	designed study, analyzed data	designed study, analyzed data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5006644	27381477	I.A.	2	designed and analyzed the calcium functional assays	designed and analyzed the calcium functional assays	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4539183	26288732	Both authors	2	have contributed in the design, data collection, as well as writing and editing the paper	have contributed in the design, data collection, as well as writing and editing the paper	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
4537535	26279668	All authors	2	conceptualized the study and wrote the proposal|participated in data analysis and wrote the manuscript|read and approved the final manuscript	conceptualized the study and wrote the proposal	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4537535	26279668	All authors	2	conceptualized the study and wrote the proposal|participated in data analysis and wrote the manuscript|read and approved the final manuscript	participated in data analysis and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4537535	26279668	All authors	2	conceptualized the study and wrote the proposal|participated in data analysis and wrote the manuscript|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4537535	26279668	Comprehensive Care Centre	2	for their support and assistance in provision of medical records, administration of the hospital and the lecturers in the department of paediatric and child health, university of nairobi for their guidance, patience, commitment and overwhelming support during the period of research	for their support and assistance in provision of medical records, administration of the hospital and the lecturers in the department of paediatric and child health, university of nairobi for their guidance, patience, commitment and overwhelming support during the period of research	-	Project administration|Supervision	YES
4537535	26279668	DW	2	supervised the work and frequently advised during the study	supervised the work and frequently advised during the study	-	Supervision	YES
4537535	26279668	HIV	2	in resource constrained settings	in resource constrained settings	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation	YES
4537535	26279668	NK	2	supervised the work and frequently advised during the study	supervised the work and frequently advised during the study	-	Supervision	YES
4537535	26279668	RN	2	supervised the work and frequently advised during the study	supervised the work and frequently advised during the study	-	Supervision	YES
5216571	28056785	CCT	2	provided assistance extracting the raw material	provided assistance extracting the raw material	Contributed reagents/materials/analysis tools	Resources	YES
5216571	28056785	CZ	2	modified the manuscript	modified the manuscript	Wrote the paper	Writing - Review & Editing	YES
5216571	28056785	JC	2	provided assistance extracting the raw material	provided assistance extracting the raw material	Contributed reagents/materials/analysis tools	Resources	YES
5216571	28056785	JX	2	provided assistance extracting the raw material	provided assistance extracting the raw material	Contributed reagents/materials/analysis tools	Resources	YES
5216571	28056785	LR	2	contributed to the conception and design of the study	contributed to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5216571	28056785	MT	2	modified the manuscript	modified the manuscript	Wrote the paper	Writing - Review & Editing	YES
5216571	28056785	SJL	2	contributed to the conception and design of the study	contributed to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5216571	28056785	WHL	2	provided assistance extracting the raw material	provided assistance extracting the raw material	Contributed reagents/materials/analysis tools	Resources	YES
5216571	28056785	XJT	2	carried out bioinformatics analyses and wrote the manuscript	carried out bioinformatics analyses and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5216571	28056785	YFX	2	carried out bioinformatics analyses and wrote the manuscript	carried out bioinformatics analyses and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5216571	28056785	YZ	2	carried out bioinformatics analyses and wrote the manuscript	carried out bioinformatics analyses and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5006661	27432718	A.H.Z.	2	measured and analyzed the human cytokine data	measured and analyzed the human cytokine data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5006661	27432718	A.J.	2	measured and analyzed the human cytokine data	measured and analyzed the human cytokine data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5006661	27432718	All authors	2	discussed, read and approved the final version of the manuscript	discussed, read and approved the final version of the manuscript	-	-	NO
5006661	27432718	B.F.	2	measured and analyzed the human cytokine data|measured and analyzed the human cytokine data	measured and analyzed the human cytokine data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5006661	27432718	B.F.	2	measured and analyzed the human cytokine data|measured and analyzed the human cytokine data	measured and analyzed the human cytokine data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5006661	27432718	D.v.d.B.	2	were involved in the data collection	were involved in the data collection	Performed the experiments	Investigation	YES
5006661	27432718	F.B.	2	measured and analyzed the human cytokine data	measured and analyzed the human cytokine data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5006661	27432718	M.C.B.	2	were involved in the data collection	were involved in the data collection	Performed the experiments	Investigation	YES
5006661	27432718	M.G.	2	measured and analyzed the human cytokine data	measured and analyzed the human cytokine data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5006661	27432718	M.V.S.	2	measured and analyzed the human cytokine data	measured and analyzed the human cytokine data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4403995	25894567	BH	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4403995	25894567	CJG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403995	25894567	CJG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403995	25894567	CJG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403995	25894567	HM	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4403995	25894567	JAG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4403995	25894567	MAM	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4403995	25894567	SLM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4403995	25894567	SLM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403995	25894567	TKHL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403995	25894567	TKHL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4403995	25894567	TKHL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403995	25894567	TKHL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403995	25894567	ZW	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5504192	28744302	CJ	2	edited the manuscript and provided guidance during experimentation	edited the manuscript and provided guidance during experimentation	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Review & Editing	YES
5504192	28744302	GL	2	performed the experiments and collected the data	performed the experiments and collected the data	Performed the experiments	Investigation	YES
5504192	28744302	JL	2	performed the experiments and collected the data	performed the experiments and collected the data	Performed the experiments	Investigation	YES
5504192	28744302	ML	2	edited the manuscript and provided guidance during experimentation	edited the manuscript and provided guidance during experimentation	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Review & Editing	YES
5504192	28744302	MW	2	initiated and designed the research|performed the experiments and collected the data|analyzed the data and wrote the manuscript	initiated and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5504192	28744302	MW	2	initiated and designed the research|performed the experiments and collected the data|analyzed the data and wrote the manuscript	performed the experiments and collected the data	Performed the experiments	Investigation	YES
5504192	28744302	MW	2	initiated and designed the research|performed the experiments and collected the data|analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5504192	28744302	WL	2	performed the experiments and collected the data	performed the experiments and collected the data	Performed the experiments	Investigation	YES
5504192	28744302	ZL	2	initiated and designed the research	initiated and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
4334769	25697328	All authors	2	contributed during the editing process and approved the final, submitted manuscript	contributed during the editing process and approved the final, submitted manuscript	Wrote the paper	Writing - Review & Editing	YES
4334769	25697328	NH	2	jointly designed the acasi survey|supervised the data analysis	jointly designed the acasi survey	Conceived and designed the experiments|Performed the experiments	Investigation	YES
4334769	25697328	NH	2	jointly designed the acasi survey|supervised the data analysis	supervised the data analysis	Analyzed the data	Formal analysis|Supervision	YES
4334769	25697328	RB	2	jointly designed the acasi survey|coordinated data collection|conducted the statistical analysis|wrote the first draft manuscript	jointly designed the acasi survey	Conceived and designed the experiments|Performed the experiments	Investigation	YES
4334769	25697328	RB	2	jointly designed the acasi survey|coordinated data collection|conducted the statistical analysis|wrote the first draft manuscript	coordinated data collection	Performed the experiments	Investigation|Project administration	YES
4334769	25697328	RB	2	jointly designed the acasi survey|coordinated data collection|conducted the statistical analysis|wrote the first draft manuscript	conducted the statistical analysis	Analyzed the data	Formal analysis	YES
4334769	25697328	RB	2	jointly designed the acasi survey|coordinated data collection|conducted the statistical analysis|wrote the first draft manuscript	wrote the first draft manuscript	Wrote the paper	Writing - Original Draft	YES
4334769	25697328	WD	2	jointly designed the acasi survey|supervised the data analysis|wrote the first draft manuscript	jointly designed the acasi survey	Conceived and designed the experiments|Performed the experiments	Investigation	YES
4334769	25697328	WD	2	jointly designed the acasi survey|supervised the data analysis|wrote the first draft manuscript	supervised the data analysis	Analyzed the data	Formal analysis|Supervision	YES
4334769	25697328	WD	2	jointly designed the acasi survey|supervised the data analysis|wrote the first draft manuscript	wrote the first draft manuscript	Wrote the paper	Writing - Original Draft	YES
4539184	26288730	AH	2	were involved in the conception, design and interpretation|collected data, reviewed relevant published literature and provided the images	were involved in the conception, design and interpretation	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
4539184	26288730	AH	2	were involved in the conception, design and interpretation|collected data, reviewed relevant published literature and provided the images	collected data, reviewed relevant published literature and provided the images	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
4539184	26288730	CK	2	were involved in the conception, design and interpretation|collected data, reviewed relevant published literature and provided the images	were involved in the conception, design and interpretation	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
4539184	26288730	CK	2	were involved in the conception, design and interpretation|collected data, reviewed relevant published literature and provided the images	collected data, reviewed relevant published literature and provided the images	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
4539184	26288730	MH	2	were involved in the conception, design and interpretation	were involved in the conception, design and interpretation	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
4539184	26288730	MW	2	were involved in the conception, design and interpretation|collected data, reviewed relevant published literature and provided the images	were involved in the conception, design and interpretation	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
4539184	26288730	MW	2	were involved in the conception, design and interpretation|collected data, reviewed relevant published literature and provided the images	collected data, reviewed relevant published literature and provided the images	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
4539184	26288730	VG	2	were involved in the conception, design and interpretation	were involved in the conception, design and interpretation	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
4539184	26288730	WP	2	were involved in the conception, design and interpretation	were involved in the conception, design and interpretation	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
4537595	26279669	AA	2	was involved in study design, and clinical analyses	was involved in study design, and clinical analyses	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
4537595	26279669	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4537595	26279669	CO	2	critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4537595	26279669	FOM	2	performed laboratory, statistical and bioinformatics analyses|co-drafted the manuscript|contributed equally to the writing of this manuscript	performed laboratory, statistical and bioinformatics analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4537595	26279669	FOM	2	performed laboratory, statistical and bioinformatics analyses|co-drafted the manuscript|contributed equally to the writing of this manuscript	co-drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4537595	26279669	FOM	2	performed laboratory, statistical and bioinformatics analyses|co-drafted the manuscript|contributed equally to the writing of this manuscript	contributed equally to the writing of this manuscript	Wrote the paper	Writing - Original Draft	YES
4537595	26279669	FOO	2	critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4537595	26279669	GA	2	critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4537595	26279669	JNK	2	critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4537595	26279669	MWK	2	performed laboratory, statistical and bioinformatics analyses|co-drafted the manuscript	performed laboratory, statistical and bioinformatics analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4537595	26279669	MWK	2	performed laboratory, statistical and bioinformatics analyses|co-drafted the manuscript	co-drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4537595	26279669	TMK	2	critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4537595	26279669	TW	2	conceived and designed the study|performed laboratory, statistical and bioinformatics analyses|co-drafted the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4537595	26279669	TW	2	conceived and designed the study|performed laboratory, statistical and bioinformatics analyses|co-drafted the manuscript	performed laboratory, statistical and bioinformatics analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4537595	26279669	TW	2	conceived and designed the study|performed laboratory, statistical and bioinformatics analyses|co-drafted the manuscript	co-drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4537595	26279669	VB	2	conceived and designed the study|contributed equally to the writing of this manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4537595	26279669	VB	2	conceived and designed the study|contributed equally to the writing of this manuscript	contributed equally to the writing of this manuscript	Wrote the paper	Writing - Original Draft	YES
5216585	28056786	AG	2	performed microarray data analysis and enrichment testing	performed microarray data analysis and enrichment testing	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5216585	28056786	DL	2	performed data analysis and drafted the manuscript	performed data analysis and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5216585	28056786	JZ	2	carried out the molecular experiment	carried out the molecular experiment	Performed the experiments	Investigation	YES
5216585	28056786	PC	2	conceived of the study, and participated in its design and coordination and helped to draft the manuscript	conceived of the study, and participated in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
5216585	28056786	PG	2	participated in the statistical analysis and the drafting of the manuscript	participated in the statistical analysis and the drafting of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5216585	28056786	RW	2	conceived of the study, and participated in its design and coordination and helped to draft the manuscript	conceived of the study, and participated in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
5216585	28056786	YW	2	carried out the molecular experiment	carried out the molecular experiment	Performed the experiments	Investigation	YES
4339242	25712590	A.S.	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
4339242	25712590	All authors	2	contributed to writing the study manuscript	contributed to writing the study manuscript	Wrote the paper	Writing - Original Draft	YES
4339242	25712590	M.N.	2	contributed to writing the study manuscript	contributed to writing the study manuscript	Wrote the paper	Writing - Original Draft	YES
4339242	25712590	R.A.F.	2	designed the study|contributed to writing the study manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
4339242	25712590	R.A.F.	2	designed the study|contributed to writing the study manuscript	contributed to writing the study manuscript	Wrote the paper	Writing - Original Draft	YES
4339242	25712590	W.N.	2	contributed to writing the study manuscript	contributed to writing the study manuscript	Wrote the paper	Writing - Original Draft	YES
4539185	26288731	CIF	7	Study Concept and Design, Literature Review, Manuscript Preparation	Study Concept and Design, Literature Review, Manuscript Preparation	Conceived and designed the experiments|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
4539185	26288731	HJMF	7	Study Concept and Design, Literature Review, Manuscript Preparation	Study Concept and Design, Literature Review, Manuscript Preparation	Conceived and designed the experiments|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
4539185	26288731	JS	7	Study Concept and Design, Manuscript Review	Study Concept and Design, Manuscript Review	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
4539185	26288731	TI	7	Study Concept and Design, Manuscript Review	Study Concept and Design, Manuscript Review	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
5006664	27426280	BW	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5006664	27426280	IC	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5006664	27426280	SH	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5006664	27426280	STP	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5006664	27426280	W. All	2	authors agreed the final version	authors agreed the final version	-	-	NO
5504195	28744291	All authors	2	contributed to drafting the paper	contributed to drafting the paper	Wrote the paper	Writing - Original Draft	YES
5504195	28744291	GS	2	designed the study|performed the simulations	designed the study	Conceived and designed the experiments	Methodology	YES
5504195	28744291	GS	2	designed the study|performed the simulations	performed the simulations	Performed the experiments	Formal analysis|Investigation	YES
5504195	28744291	JFM	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5504195	28744291	KO	2	measured field data	measured field data	Performed the experiments	Investigation	YES
5504195	28744291	MY	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5504195	28744291	NM	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5504195	28744291	NY	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
4403996	25894250	BL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403996	25894250	BL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403996	25894250	BL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403996	25894250	LQ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4403996	25894250	LQ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403996	25894250	LQ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403996	25894250	LQ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403996	25894250	MX	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4403996	25894250	MX	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403996	25894250	MZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403996	25894250	MZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4403996	25894250	MZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403996	25894250	MZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403996	25894250	MZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403996	25894250	QW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403996	25894250	QW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4403996	25894250	QW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403996	25894250	QW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403996	25894250	QW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403996	25894250	WG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4403996	25894250	WW	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403996	25894250	WW	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4403996	25894250	WW	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403996	25894250	WW	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403996	25894250	YX	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4543466	26300948	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4543466	26300948	HL	2	were responsible for patient follow-up and data collection	were responsible for patient follow-up and data collection	Performed the experiments	Investigation	YES
4543466	26300948	HQL	2	were responsible for patient follow-up and data collection	were responsible for patient follow-up and data collection	Performed the experiments	Investigation	YES
4543466	26300948	HW	2	were responsible for study concept and study design	were responsible for study concept and study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4543466	26300948	HWZ	2	were responsible for study concept and study design|were responsible for patient follow-up and data collection|wrote the manuscript	were responsible for study concept and study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4543466	26300948	HWZ	2	were responsible for study concept and study design|were responsible for patient follow-up and data collection|wrote the manuscript	were responsible for patient follow-up and data collection	Performed the experiments	Investigation	YES
4543466	26300948	HWZ	2	were responsible for study concept and study design|were responsible for patient follow-up and data collection|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4543466	26300948	HXZ	2	were responsible for patient follow-up and data collection	were responsible for patient follow-up and data collection	Performed the experiments	Investigation	YES
4543466	26300948	JJL	2	were responsible for patient follow-up and data collection	were responsible for patient follow-up and data collection	Performed the experiments	Investigation	YES
4543466	26300948	KZ	2	were responsible for patient follow-up and data collection	were responsible for patient follow-up and data collection	Performed the experiments	Investigation	YES
4543466	26300948	MZ	2	were responsible for patient follow-up and data collection	were responsible for patient follow-up and data collection	Performed the experiments	Investigation	YES
4543466	26300948	NH	2	were responsible for patient follow-up and data collection	were responsible for patient follow-up and data collection	Performed the experiments	Investigation	YES
4543466	26300948	QL	2	were responsible for patient follow-up and data collection	were responsible for patient follow-up and data collection	Performed the experiments	Investigation	YES
4543466	26300948	QXZ	2	were responsible for patient follow-up and data collection	were responsible for patient follow-up and data collection	Performed the experiments	Investigation	YES
4543466	26300948	TZ	2	were responsible for study concept and study design|wrote the manuscript	were responsible for study concept and study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4543466	26300948	TZ	2	were responsible for study concept and study design|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4543466	26300948	WPC	2	were responsible for study concept and study design|were responsible for patient follow-up and data collection	were responsible for study concept and study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4543466	26300948	WPC	2	were responsible for study concept and study design|were responsible for patient follow-up and data collection	were responsible for patient follow-up and data collection	Performed the experiments	Investigation	YES
4543466	26300948	WX	2	were responsible for data analysis and data interpretation	were responsible for data analysis and data interpretation	Analyzed the data	Formal analysis	YES
4543466	26300948	YH	2	were responsible for patient follow-up and data collection	were responsible for patient follow-up and data collection	Performed the experiments	Investigation	YES
4543466	26300948	YTS	2	were responsible for patient follow-up and data collection	were responsible for patient follow-up and data collection	Performed the experiments	Investigation	YES
4543466	26300948	ZL	2	were responsible for data analysis and data interpretation	were responsible for data analysis and data interpretation	Analyzed the data	Formal analysis	YES
4543466	26300948	ZYL	2	were responsible for data analysis and data interpretation	were responsible for data analysis and data interpretation	Analyzed the data	Formal analysis	YES
4543083	26468369	Nigel Suggett	7	Supervision, review and editing of paper	Supervision, review and editing of paper	Wrote the paper	Supervision|Writing - Review & Editing	YES
4543083	26468369	Peter Thomson	7	Data collection from medical paper and electronic records	Data collection from medical paper and electronic records	Performed the experiments	Investigation	YES
4543083	26468369	Stephen Stonelake	7	Data collection from medical paper and electronic records, statistical analysis	Data collection from medical paper and electronic records, statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5216591	28056764	All authors	2	critiqued and edited the final manuscript	critiqued and edited the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5216591	28056764	IB	2	designed experiments|interpreted experimental results	designed experiments	Conceived and designed the experiments	Methodology	YES
5216591	28056764	IB	2	designed experiments|interpreted experimental results	interpreted experimental results	Analyzed the data	Formal analysis	YES
5216591	28056764	ML	2	designed experiments|performed experiments|interpreted experimental results|wrote the manuscript	designed experiments	Conceived and designed the experiments	Methodology	YES
5216591	28056764	ML	2	designed experiments|performed experiments|interpreted experimental results|wrote the manuscript	performed experiments	Performed the experiments	Investigation	YES
5216591	28056764	ML	2	designed experiments|performed experiments|interpreted experimental results|wrote the manuscript	interpreted experimental results	Analyzed the data	Formal analysis	YES
5216591	28056764	ML	2	designed experiments|performed experiments|interpreted experimental results|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5216591	28056764	NP	2	designed experiments|performed bioinformatics analyses|interpreted experimental results|wrote the manuscript	designed experiments	Conceived and designed the experiments	Methodology	YES
5216591	28056764	NP	2	designed experiments|performed bioinformatics analyses|interpreted experimental results|wrote the manuscript	performed bioinformatics analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5216591	28056764	NP	2	designed experiments|performed bioinformatics analyses|interpreted experimental results|wrote the manuscript	interpreted experimental results	Analyzed the data	Formal analysis	YES
5216591	28056764	NP	2	designed experiments|performed bioinformatics analyses|interpreted experimental results|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5216591	28056764	PR	2	designed experiments|performed bioinformatics analyses|interpreted experimental results	designed experiments	Conceived and designed the experiments	Methodology	YES
5216591	28056764	PR	2	designed experiments|performed bioinformatics analyses|interpreted experimental results	performed bioinformatics analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5216591	28056764	PR	2	designed experiments|performed bioinformatics analyses|interpreted experimental results	interpreted experimental results	Analyzed the data	Formal analysis	YES
5216591	28056764	RS	2	designed experiments	designed experiments	Conceived and designed the experiments	Methodology	YES
5504226	28744297	HC	2	conducted experiments	conducted experiments	Performed the experiments	Investigation	YES
5504226	28744297	JP	2	analyzed data|wrote the manuscript	analyzed data	Analyzed the data	Formal analysis	YES
5504226	28744297	JP	2	analyzed data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5504226	28744297	MS	2	conceived and designed research|analyzed data|wrote the manuscript	conceived and designed research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5504226	28744297	MS	2	conceived and designed research|analyzed data|wrote the manuscript	analyzed data	Analyzed the data	Formal analysis	YES
5504226	28744297	MS	2	conceived and designed research|analyzed data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5504226	28744297	SJ	2	conceived and designed research|conducted experiments|analyzed data|wrote the manuscript	conceived and designed research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5504226	28744297	SJ	2	conceived and designed research|conducted experiments|analyzed data|wrote the manuscript	conducted experiments	Performed the experiments	Investigation	YES
5504226	28744297	SJ	2	conceived and designed research|conducted experiments|analyzed data|wrote the manuscript	analyzed data	Analyzed the data	Formal analysis	YES
5504226	28744297	SJ	2	conceived and designed research|conducted experiments|analyzed data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5504226	28744297	YG	2	conceived and designed research|conducted experiments	conceived and designed research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5504226	28744297	YG	2	conceived and designed research|conducted experiments	conducted experiments	Performed the experiments	Investigation	YES
4344535	25724503	AK	2	collectively designed the outline of the review and wrote the manuscript	collectively designed the outline of the review and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4344535	25724503	LSH	2	collectively designed the outline of the review and wrote the manuscript	collectively designed the outline of the review and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4344535	25724503	NK	2	collectively designed the outline of the review and wrote the manuscript	collectively designed the outline of the review and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4344535	25724503	PL	2	collectively designed the outline of the review and wrote the manuscript	collectively designed the outline of the review and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4344535	25724503	YKP	2	their adherence to therapy|key populations in general, and formatted the paper	their adherence to therapy	-	-	NO
4344535	25724503	YKP	2	their adherence to therapy|key populations in general, and formatted the paper	key populations in general, and formatted the paper	-	-	NO
4403998	25894559	BE	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403998	25894559	BE	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403998	25894559	BE	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403998	25894559	BE	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403998	25894559	BF	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403998	25894559	BF	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4403998	25894559	BF	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403998	25894559	BF	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403998	25894559	HL	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403998	25894559	HL	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4403998	25894559	HL	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403998	25894559	HL	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403998	25894559	JMB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403998	25894559	JMB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403998	25894559	JMB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403998	25894559	MWN	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403998	25894559	MWN	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403998	25894559	MWN	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403998	25894559	NRO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403998	25894559	NRO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4403998	25894559	NRO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4403998	25894559	NRO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403998	25894559	NRO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4403998	25894559	PB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4403998	25894559	PB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4403998	25894559	PB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4578665	26396584	AA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data and prepared manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4578665	26396584	AA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data and prepared manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4578665	26396584	AA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data and prepared manuscript	Analyzed the data and prepared manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4578665	26396584	AK	PLoS5	Conceived and designed the experiments|Analyzed the data and prepared manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4578665	26396584	AK	PLoS5	Conceived and designed the experiments|Analyzed the data and prepared manuscript	Analyzed the data and prepared manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4578665	26396584	AN	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4578665	26396584	CM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data and prepared manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4578665	26396584	CM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data and prepared manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4578665	26396584	CM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data and prepared manuscript	Analyzed the data and prepared manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4578665	26396584	LA	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4578665	26396584	LA	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4578665	26396584	NS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4578665	26396584	PNA	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4578665	26396584	PSSR	PLoS5	Analyzed the data and prepared manuscript	Analyzed the data and prepared manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4578665	26396584	SK	PLoS5	Conceived and designed the experiments|Analyzed the data and prepared manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4578665	26396584	SK	PLoS5	Conceived and designed the experiments|Analyzed the data and prepared manuscript	Analyzed the data and prepared manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4556781	26468371	Catrin Morgan	7	Study design	Study design	Conceived and designed the experiments	Methodology	YES
4556781	26468371	Nirav Amin	7	Study concept, data collection & writing the paper	Study concept, data collection & writing the paper	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
4556781	26468371	Priyank Patel	7	Study concept, data interpretation & writing the paper	Study concept, data interpretation & writing the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
4556781	26468371	Shreya Patel	7	Study concept & design	Study concept & design	Conceived and designed the experiments	Conceptualization|Methodology	YES
521684	15453915	MV	2	provided guidance for the computational work	provided guidance for the computational work	-	Formal analysis|Supervision	YES
521684	15453915	SG	2	wrote the prediction software as well as designed pcr primers for experimental analysis	wrote the prediction software as well as designed pcr primers for experimental analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Software|Writing - Original Draft	YES
521684	15453915	SH	2	provided guidance for the computational work	provided guidance for the computational work	-	Formal analysis|Supervision	YES
5006730	27448760	A.M.J.	2	performed experiments and analyzed the data	performed experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5006730	27448760	J.W.	2	performed experiments and analyzed the data	performed experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5006730	27448760	J.Z.	2	jointly designed, performed experiments, analyzed the data and wrote the manuscript	jointly designed, performed experiments, analyzed the data and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5006730	27448760	L.Z.	2	performed experiments and analyzed the data	performed experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5006730	27448760	R.K.M.	2	performed experiments and analyzed the data	performed experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5006730	27448760	S.D.	2	performed experiments and analyzed the data	performed experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5006730	27448760	Y.Z.	2	jointly designed, performed experiments, analyzed the data and wrote the manuscript|oversaw and directed the study	jointly designed, performed experiments, analyzed the data and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5006730	27448760	Y.Z.	2	jointly designed, performed experiments, analyzed the data and wrote the manuscript|oversaw and directed the study	oversaw and directed the study	-	Supervision	YES
4404048	25894336	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404048	25894336	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404048	25894336	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404048	25894336	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404048	25894336	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404048	25894336	ARF	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404048	25894336	ARF	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404048	25894336	BZ	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4404048	25894336	BZ	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404048	25894336	FK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404048	25894336	FK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404048	25894336	FK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404048	25894336	FK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404048	25894336	ID	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404048	25894336	ID	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404048	25894336	ID	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404048	25894336	JP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404048	25894336	JP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4404048	25894336	JP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4404048	25894336	JS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404048	25894336	JS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404048	25894336	JS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404048	25894336	JS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404048	25894336	PB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404048	25894336	PB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404048	25894336	PB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5504228	28744299	BR	2	initiated and designed the research|performed the experiments, analyzed the data, and wrote the manuscript	initiated and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5504228	28744299	BR	2	initiated and designed the research|performed the experiments, analyzed the data, and wrote the manuscript	performed the experiments, analyzed the data, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5504228	28744299	BZ	2	revised and edited the manuscript and also provided advice on the experiments	revised and edited the manuscript and also provided advice on the experiments	Wrote the paper	Writing - Review & Editing	YES
5504228	28744299	JZ	2	initiated and designed the research|revised and edited the manuscript and also provided advice on the experiments	initiated and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5504228	28744299	JZ	2	initiated and designed the research|revised and edited the manuscript and also provided advice on the experiments	revised and edited the manuscript and also provided advice on the experiments	Wrote the paper	Writing - Review & Editing	YES
5504228	28744299	PL	2	revised and edited the manuscript and also provided advice on the experiments	revised and edited the manuscript and also provided advice on the experiments	Wrote the paper	Writing - Review & Editing	YES
5504228	28744299	SD	2	revised and edited the manuscript and also provided advice on the experiments	revised and edited the manuscript and also provided advice on the experiments	Wrote the paper	Writing - Review & Editing	YES
5217208	28056781	AJ	2	wrote and edited the manuscript|supervised the project	wrote and edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5217208	28056781	AJ	2	wrote and edited the manuscript|supervised the project	supervised the project	-	Supervision	YES
5217208	28056781	BG	2	performed the majority of work described here|wrote and edited the manuscript	performed the majority of work described here	Performed the experiments	Investigation	YES
5217208	28056781	BG	2	performed the majority of work described here|wrote and edited the manuscript	wrote and edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5217208	28056781	TCF	2	wrote and edited the manuscript|supervised the project	wrote and edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5217208	28056781	TCF	2	wrote and edited the manuscript|supervised the project	supervised the project	-	Supervision	YES
4580116	26401157	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4580116	26401157	Carmen Delport	2	who were involved in data collection	who were involved in data collection	Performed the experiments	Investigation	YES
4580116	26401157	J-RV	2	wrote the first draft of the manuscript|performed the statistical analyses under supervision	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
4580116	26401157	J-RV	2	wrote the first draft of the manuscript|performed the statistical analyses under supervision	performed the statistical analyses under supervision	Analyzed the data	Formal analysis|Supervision	YES
4580116	26401157	JAD	2	participated in the design and coordination of the study, and reviewing the manuscript	participated in the design and coordination of the study, and reviewing the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Review & Editing	YES
4580116	26401157	JMH	2	wrote the first draft of the manuscript|conceived the idea of the study and participated in its design	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
4580116	26401157	JMH	2	wrote the first draft of the manuscript|conceived the idea of the study and participated in its design	conceived the idea of the study and participated in its design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4580116	26401157	Jean Maritz	2	as well as the study coordinator	as well as the study coordinator	-	Project administration	YES
4580116	26401157	Johan van der Watt	2	as well as the study coordinator	as well as the study coordinator	-	Project administration	YES
4580116	26401157	NSL	2	participated in the design and coordination of the study, and reviewing the manuscript	participated in the design and coordination of the study, and reviewing the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Review & Editing	YES
4344537	25724507	AP	2	all helped conceptualize the study, write and edit the manuscript	all helped conceptualize the study, write and edit the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
4344537	25724507	CC	2	all helped conceptualize the study, write and edit the manuscript	all helped conceptualize the study, write and edit the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
4344537	25724507	FC	2	all helped conceptualize the study, write and edit the manuscript	all helped conceptualize the study, write and edit the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
4344537	25724507	LHW	2	all helped conceptualize the study, write and edit the manuscript	all helped conceptualize the study, write and edit the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
4344537	25724507	NN	2	all helped conceptualize the study, write and edit the manuscript	all helped conceptualize the study, write and edit the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
4344537	25724507	VG	2	all helped conceptualize the study, write and edit the manuscript	all helped conceptualize the study, write and edit the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
4556812	26468374	A. A. Khan	2	designed concept for the study|provided data analysis and interpretations, drafting of the manuscript and critical revision of manuscript and final approval to submit the manuscript	designed concept for the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4556812	26468374	A. A. Khan	2	designed concept for the study|provided data analysis and interpretations, drafting of the manuscript and critical revision of manuscript and final approval to submit the manuscript	provided data analysis and interpretations, drafting of the manuscript and critical revision of manuscript and final approval to submit the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft|Writing - Review & Editing	YES
4556812	26468374	All authors	2	named involved with data collection	named involved with data collection	Performed the experiments	Investigation	YES
4556812	26468374	J. G. Hubbard	2	designed concept for the study|provided data analysis and interpretations, drafting of the manuscript and critical revision of manuscript and final approval to submit the manuscript	designed concept for the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4556812	26468374	J. G. Hubbard	2	designed concept for the study|provided data analysis and interpretations, drafting of the manuscript and critical revision of manuscript and final approval to submit the manuscript	provided data analysis and interpretations, drafting of the manuscript and critical revision of manuscript and final approval to submit the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft|Writing - Review & Editing	YES
4404049	25893685	JW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404049	25893685	JW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404049	25893685	JW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404049	25893685	JW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404049	25893685	ML	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4404049	25893685	RZ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404049	25893685	RZ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404049	25893685	RZ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404049	25893685	SB	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404049	25893685	WY	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404049	25893685	XG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5217214	28056765	RA	2	reviewed and approved the final manuscript	reviewed and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5217214	28056765	SS	2	reviewed and approved the final manuscript	reviewed and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5217214	28056765	SW	2	performed analysis on the quantification data and drafted the manuscript	performed analysis on the quantification data and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5217214	28056765	TP	2	reviewed and approved the final manuscript	reviewed and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4556813	26468373	Anais Rosich-Medina	7	study design, data collection, data analysis, writing	study design, data collection, data analysis, writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology	YES
4556813	26468373	Charles Malata	7	study design, data collection, data analysis, editing manuscript	study design, data collection, data analysis, editing manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Review & Editing	YES
4556813	26468373	Michele Di Candia	7	data collection, editing manuscript	data collection, editing manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4556813	26468373	Serafeim Bouloumpasis	7	data collection, data analysis	data collection, data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5504235	28744300	BH	2	conceived and designed the experiments and wrote the manuscript	conceived and designed the experiments and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
5504235	28744300	DJ	2	performed experiments, analyzed data and wrote the manuscript	performed experiments, analyzed data and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5504235	28744300	MS	2	experiments and data analysis	experiments and data analysis	Analyzed the data	Formal analysis	YES
4582634	26413132	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4461734	26106610	E. Mari	2	equally contributed to the work	equally contributed to the work	-	-	NO
4461734	26106610	S. Mardente	2	equally contributed to the work	equally contributed to the work	-	-	NO
4344538	25724506	JDF	2	contributed sections on consent, developmental issues and the initial figure graphic	contributed sections on consent, developmental issues and the initial figure graphic	-	Visualization	YES
4404050	25894519	CSLV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Read and approved the final manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404050	25894519	CSLV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Read and approved the final manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4404050	25894519	CSLV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Read and approved the final manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4404050	25894519	CSLV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Read and approved the final manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404050	25894519	CSLV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Read and approved the final manuscript	Read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4404050	25894519	KH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Read and approved the final manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404050	25894519	KH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Read and approved the final manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4404050	25894519	KH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Read and approved the final manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4404050	25894519	KH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Read and approved the final manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404050	25894519	KH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Read and approved the final manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404050	25894519	KH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Read and approved the final manuscript	Read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4404050	25894519	MM	PLoS5	Contributed reagents/materials/analysis tools|Read and approved the final manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404050	25894519	MM	PLoS5	Contributed reagents/materials/analysis tools|Read and approved the final manuscript	Read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4404050	25894519	RS	PLoS5	Analyzed the data|Read and approved the final manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4404050	25894519	RS	PLoS5	Analyzed the data|Read and approved the final manuscript	Read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4404050	25894519	YI	PLoS5	Performed the experiments|Read and approved the final manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4404050	25894519	YI	PLoS5	Performed the experiments|Read and approved the final manuscript	Read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5217215	28056803	All authors	2	contributed to the preparation of the final version	contributed to the preparation of the final version	-	-	NO
5217215	28056803	CHR	2	conceived and designed the study|drafted the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5217215	28056803	CHR	2	conceived and designed the study|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5217215	28056803	DBY	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5217215	28056803	HZY	2	conceived and designed the study|drafted the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5217215	28056803	HZY	2	conceived and designed the study|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5217215	28056803	LC	2	conceived and designed the study|drafted the manuscript|conducted the sample collection, library construction, data processing, bioinformatics analysis, rt pcr and qrt pcr	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5217215	28056803	LC	2	conceived and designed the study|drafted the manuscript|conducted the sample collection, library construction, data processing, bioinformatics analysis, rt pcr and qrt pcr	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5217215	28056803	LC	2	conceived and designed the study|drafted the manuscript|conducted the sample collection, library construction, data processing, bioinformatics analysis, rt pcr and qrt pcr	conducted the sample collection, library construction, data processing, bioinformatics analysis, rt pcr and qrt pcr	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5217215	28056803	ZYW	2	coordinated the study	coordinated the study	-	Project administration	YES
5036513	27515689	AC	2	collected data for the radiogen study	collected data for the radiogen study	Performed the experiments	Investigation	YES
5036513	27515689	AGC	2	collected data for the radiogen study	collected data for the radiogen study	Performed the experiments	Investigation	YES
5036513	27515689	AMC	2	collected data for the radiogen study	collected data for the radiogen study	Performed the experiments	Investigation	YES
5036513	27515689	AMD	2	contributed to the data analysis plan and statistical methods used	contributed to the data analysis plan and statistical methods used	Performed the experiments|Analyzed the data	Formal analysis	YES
5036513	27515689	AV	2	collected data for the radiogen study|was the principal investigator for the radiogen study	collected data for the radiogen study	Performed the experiments	Investigation	YES
5036513	27515689	AV	2	collected data for the radiogen study|was the principal investigator for the radiogen study	was the principal investigator for the radiogen study	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
5036513	27515689	All authors	2	contributed intellectual input to the study design and interpretation of results, and all authors reviewed the manuscript prior to submission	contributed intellectual input to the study design and interpretation of results, and all authors reviewed the manuscript prior to submission	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
5036513	27515689	BSR	2	collected data for the gene-pare study|were the principal investigators for the gene-pare study	collected data for the gene-pare study	Performed the experiments	Investigation	YES
5036513	27515689	BSR	2	collected data for the gene-pare study|were the principal investigators for the gene-pare study	were the principal investigators for the gene-pare study	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
5036513	27515689	CMLW	2	collected data for the rapper study|were the principal investigators for the rapper study|contributed to the data analysis plan and statistical methods used|approved the final manuscript for submission	collected data for the rapper study	Performed the experiments	Investigation	YES
5036513	27515689	CMLW	2	collected data for the rapper study|were the principal investigators for the rapper study|contributed to the data analysis plan and statistical methods used|approved the final manuscript for submission	were the principal investigators for the rapper study	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
5036513	27515689	CMLW	2	collected data for the rapper study|were the principal investigators for the rapper study|contributed to the data analysis plan and statistical methods used|approved the final manuscript for submission	contributed to the data analysis plan and statistical methods used	Performed the experiments|Analyzed the data	Formal analysis	YES
5036513	27515689	CMLW	2	collected data for the rapper study|were the principal investigators for the rapper study|contributed to the data analysis plan and statistical methods used|approved the final manuscript for submission	approved the final manuscript for submission	Wrote the paper	Writing - Review & Editing	YES
5036513	27515689	DPD	2	collected data for the rapper study	collected data for the rapper study	Performed the experiments	Investigation	YES
5036513	27515689	DRB	2	contributed to the data analysis plan and statistical methods used	contributed to the data analysis plan and statistical methods used	Performed the experiments|Analyzed the data	Formal analysis	YES
5036513	27515689	EH	2	collected data for the rapper study	collected data for the rapper study	Performed the experiments	Investigation	YES
5036513	27515689	GCB	2	analyzed and interpreted data and drafted the initial manuscript|collected data for the rapper study|contributed to the data analysis plan and statistical methods used	analyzed and interpreted data and drafted the initial manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5036513	27515689	GCB	2	analyzed and interpreted data and drafted the initial manuscript|collected data for the rapper study|contributed to the data analysis plan and statistical methods used	collected data for the rapper study	Performed the experiments	Investigation	YES
5036513	27515689	GCB	2	analyzed and interpreted data and drafted the initial manuscript|collected data for the rapper study|contributed to the data analysis plan and statistical methods used	contributed to the data analysis plan and statistical methods used	Performed the experiments|Analyzed the data	Formal analysis	YES
5036513	27515689	HO	2	collected data for the gene-pare study|were the principal investigators for the gene-pare study|contributed to the data analysis plan and statistical methods used	collected data for the gene-pare study	Performed the experiments	Investigation	YES
5036513	27515689	HO	2	collected data for the gene-pare study|were the principal investigators for the gene-pare study|contributed to the data analysis plan and statistical methods used	were the principal investigators for the gene-pare study	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
5036513	27515689	HO	2	collected data for the gene-pare study|were the principal investigators for the gene-pare study|contributed to the data analysis plan and statistical methods used	contributed to the data analysis plan and statistical methods used	Performed the experiments|Analyzed the data	Formal analysis	YES
5036513	27515689	JPT	2	contributed to the data analysis plan and statistical methods used	contributed to the data analysis plan and statistical methods used	Performed the experiments|Analyzed the data	Formal analysis	YES
5036513	27515689	KM	2	contributed to the data analysis plan and statistical methods used	contributed to the data analysis plan and statistical methods used	Performed the experiments|Analyzed the data	Formal analysis	YES
5036513	27515689	LD	2	analyzed and interpreted data and drafted the initial manuscript|contributed to the data analysis plan and statistical methods used	analyzed and interpreted data and drafted the initial manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5036513	27515689	LD	2	analyzed and interpreted data and drafted the initial manuscript|contributed to the data analysis plan and statistical methods used	contributed to the data analysis plan and statistical methods used	Performed the experiments|Analyzed the data	Formal analysis	YES
5036513	27515689	LF	2	analyzed and interpreted data and drafted the initial manuscript|contributed to the data analysis plan and statistical methods used	analyzed and interpreted data and drafted the initial manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5036513	27515689	LF	2	analyzed and interpreted data and drafted the initial manuscript|contributed to the data analysis plan and statistical methods used	contributed to the data analysis plan and statistical methods used	Performed the experiments|Analyzed the data	Formal analysis	YES
5036513	27515689	MP	2	collected data for the cci study|was the principal investigator for the cci study	collected data for the cci study	Performed the experiments	Investigation	YES
5036513	27515689	MP	2	collected data for the cci study|was the principal investigator for the cci study	was the principal investigator for the cci study	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
5036513	27515689	MRS	2	collected data for the rapper study	collected data for the rapper study	Performed the experiments	Investigation	YES
5036513	27515689	MS	2	collected data for the cci study	collected data for the cci study	Performed the experiments	Investigation	YES
5036513	27515689	NGB	2	collected data for the rapper study|were the principal investigators for the rapper study	collected data for the rapper study	Performed the experiments	Investigation	YES
5036513	27515689	NGB	2	collected data for the rapper study|were the principal investigators for the rapper study	were the principal investigators for the rapper study	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
5036513	27515689	NNS	2	collected data for the gene-pare study	collected data for the gene-pare study	Performed the experiments	Investigation	YES
5036513	27515689	PDPP	2	contributed to the data analysis plan and statistical methods used	contributed to the data analysis plan and statistical methods used	Performed the experiments|Analyzed the data	Formal analysis	YES
5036513	27515689	PP	2	collected data for the radiogen study	collected data for the radiogen study	Performed the experiments	Investigation	YES
5036513	27515689	RS	2	collected data for the gene-pare study	collected data for the gene-pare study	Performed the experiments	Investigation	YES
5036513	27515689	SA	2	designed and performed taqman genotyping assays	designed and performed taqman genotyping assays	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5036513	27515689	SB	2	contributed to the data analysis plan and statistical methods used	contributed to the data analysis plan and statistical methods used	Performed the experiments|Analyzed the data	Formal analysis	YES
5036513	27515689	SLG	2	collected data for the rapper study	collected data for the rapper study	Performed the experiments	Investigation	YES
5036513	27515689	SLK	2	analyzed and interpreted data and drafted the initial manuscript|collected data for the gene-pare study|contributed to the data analysis plan and statistical methods used	analyzed and interpreted data and drafted the initial manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5036513	27515689	SLK	2	analyzed and interpreted data and drafted the initial manuscript|collected data for the gene-pare study|contributed to the data analysis plan and statistical methods used	collected data for the gene-pare study	Performed the experiments	Investigation	YES
5036513	27515689	SLK	2	analyzed and interpreted data and drafted the initial manuscript|collected data for the gene-pare study|contributed to the data analysis plan and statistical methods used	contributed to the data analysis plan and statistical methods used	Performed the experiments|Analyzed the data	Formal analysis	YES
4582728	26413133	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4582728	26413133	JJ	2	helped to collect and manage data	helped to collect and manage data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
4582728	26413133	JLZ	2	helped to collect and manage data	helped to collect and manage data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
4582728	26413133	JMJ	2	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
4582728	26413133	JZY	2	helped to collect and manage data	helped to collect and manage data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
4582728	26413133	LC	2	carried out study design as well as data collection, data analysis, and write manuscript	carried out study design as well as data collection, data analysis, and write manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4582728	26413133	LH	2	helped to collect and manage data	helped to collect and manage data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
4582728	26413133	NW	2	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
4582728	26413133	PCY	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4582728	26413133	RJZ	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4582728	26413133	XHP	2	designed the study, reviewed the manuscript and approved the final version	designed the study, reviewed the manuscript and approved the final version	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
4582728	26413133	YX	2	helped to collect and manage data	helped to collect and manage data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5504242	28744295	B-hL	PLoS52	conceived and designed the research|discussed the results and wrote the paper	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5504242	28744295	B-hL	PLoS52	conceived and designed the research|discussed the results and wrote the paper	discussed the results and wrote the paper	Wrote the paper	Writing - Original Draft	YES
5504242	28744295	HA	PLoS52	performed the experiments|discussed the results and wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5504242	28744295	HA	PLoS52	performed the experiments|discussed the results and wrote the paper	discussed the results and wrote the paper	Wrote the paper	Writing - Original Draft	YES
5504242	28744295	HL	PLoS52	conceived and designed the research|discussed the results and wrote the paper	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5504242	28744295	HL	PLoS52	conceived and designed the research|discussed the results and wrote the paper	discussed the results and wrote the paper	Wrote the paper	Writing - Original Draft	YES
5504242	28744295	MP	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
4344539	25724511	All authors	2	contributed to the initial outline of the paper, and reviewed sections of the literature, and approved the initial submission	contributed to the initial outline of the paper, and reviewed sections of the literature, and approved the initial submission	-	Formal analysis	YES
4344539	25724511	SD	2	wrote the initial draft of the paper which all authors reviewed, and coordinated subsequent revisions	wrote the initial draft of the paper which all authors reviewed, and coordinated subsequent revisions	Wrote the paper	Project administration|Writing - Original Draft|Writing - Review & Editing	YES
4404051	25893524	DS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404051	25893524	DS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404051	25893524	DS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404051	25893524	JW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4404051	25893524	KT	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4404051	25893524	LL	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4404051	25893524	QC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4404051	25893524	SW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404051	25893524	SW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404051	25893524	SW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404051	25893524	WM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404051	25893524	WM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404051	25893524	WM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404051	25893524	WZ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404051	25893524	WZ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404051	25893524	WZ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404051	25893524	XY	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4404051	25893524	XZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4404051	25893524	YJ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4404051	25893524	ZY	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5049924	27528268	Dana M. Spence	2	study concept and design, analysis and interpretation of data, study supervision, critical revision of manuscript for intellectual content	study concept and design, analysis and interpretation of data, study supervision, critical revision of manuscript for intellectual content	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Supervision|Writing - Review & Editing	YES
5049924	27528268	Eric Eggenberger	2	study design, interpretation of data, study supervision, critical revision of manuscript for intellectual content	study design, interpretation of data, study supervision, critical revision of manuscript for intellectual content	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Supervision|Writing - Review & Editing	YES
5049924	27528268	Sarah Y. Lockwood	2	patient consent, analysis and interpretation of data	patient consent, analysis and interpretation of data	Analyzed the data	Formal analysis	YES
5049924	27528268	Suzanne Summers	2	acquisition of data, analysis and interpretation of data	acquisition of data, analysis and interpretation of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4589178	26425133	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4589178	26425133	HH	2	carried out the aspects of clinical practice related to this case, collected the patients data, and drafted the manuscript	carried out the aspects of clinical practice related to this case, collected the patients data, and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4589178	26425133	HY	2	supervised the draft process	supervised the draft process	Wrote the paper	Supervision|Writing - Original Draft	YES
4589178	26425133	SH	2	carried out the aspects of clinical practice related to this case, collected the patients data, and drafted the manuscript|supervised the draft process	carried out the aspects of clinical practice related to this case, collected the patients data, and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4589178	26425133	SH	2	carried out the aspects of clinical practice related to this case, collected the patients data, and drafted the manuscript|supervised the draft process	supervised the draft process	Wrote the paper	Supervision|Writing - Original Draft	YES
4589178	26425133	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5504246	28744296	GC	2	contributed to the conception of the study	contributed to the conception of the study	Conceived and designed the experiments	Conceptualization	YES
5504246	28744296	HC	2	contributed to the conception of the study	contributed to the conception of the study	Conceived and designed the experiments	Conceptualization	YES
5504246	28744296	HX	2	contributed significantly to analysis and manuscript preparation	contributed significantly to analysis and manuscript preparation	Wrote the paper	Writing - Original Draft	YES
5504246	28744296	LJ	2	helped perform the analysis with constructive discussions	helped perform the analysis with constructive discussions	Performed the experiments	Investigation	YES
5504246	28744296	NS	2	helped perform the analysis with constructive discussions	helped perform the analysis with constructive discussions	Performed the experiments	Investigation	YES
5504246	28744296	PT	2	helped perform the analysis with constructive discussions	helped perform the analysis with constructive discussions	Performed the experiments	Investigation	YES
5504246	28744296	TS	2	contributed significantly to analysis and manuscript preparation|performed the data analyses and wrote the manuscript	contributed significantly to analysis and manuscript preparation	Wrote the paper	Writing - Original Draft	YES
5504246	28744296	TS	2	contributed significantly to analysis and manuscript preparation|performed the data analyses and wrote the manuscript	performed the data analyses and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5504246	28744296	WY	2	helped perform the analysis with constructive discussions	helped perform the analysis with constructive discussions	Performed the experiments	Investigation	YES
5504246	28744296	YY	2	helped perform the analysis with constructive discussions	helped perform the analysis with constructive discussions	Performed the experiments	Investigation	YES
5217216	28056783	JL	2	performed the experiments and molecular biological work	performed the experiments and molecular biological work	Performed the experiments	Investigation	YES
5217216	28056783	JvH	2	performed the experiments and molecular biological work|performed the in silico analysis|did the experimental work to confirm the transcriptome data|was responsible for writing the manuscript	performed the experiments and molecular biological work	Performed the experiments	Investigation	YES
5217216	28056783	JvH	2	performed the experiments and molecular biological work|performed the in silico analysis|did the experimental work to confirm the transcriptome data|was responsible for writing the manuscript	performed the in silico analysis	Performed the experiments	Formal analysis|Investigation	YES
5217216	28056783	JvH	2	performed the experiments and molecular biological work|performed the in silico analysis|did the experimental work to confirm the transcriptome data|was responsible for writing the manuscript	did the experimental work to confirm the transcriptome data	Performed the experiments	Investigation	YES
5217216	28056783	JvH	2	performed the experiments and molecular biological work|performed the in silico analysis|did the experimental work to confirm the transcriptome data|was responsible for writing the manuscript	was responsible for writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5217216	28056783	MS	2	performed the experiments and molecular biological work	performed the experiments and molecular biological work	Performed the experiments	Investigation	YES
5217216	28056783	SS	2	performed the in silico analysis|was responsible for writing the manuscript|were responsible for project planning	performed the in silico analysis	Performed the experiments	Formal analysis|Investigation	YES
5217216	28056783	SS	2	performed the in silico analysis|was responsible for writing the manuscript|were responsible for project planning	was responsible for writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5217216	28056783	SS	2	performed the in silico analysis|was responsible for writing the manuscript|were responsible for project planning	were responsible for project planning	Conceived and designed the experiments	Methodology	YES
5217216	28056783	US	2	was responsible for writing the manuscript|were responsible for project planning	was responsible for writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5217216	28056783	US	2	was responsible for writing the manuscript|were responsible for project planning	were responsible for project planning	Conceived and designed the experiments	Methodology	YES
4344540	25724512	All	2	gave editorial input and all have signed off the final copy	gave editorial input and all have signed off the final copy	-	-	NO
4344540	25724512	The authors	2	jointly designed and wrote this editorial	jointly designed and wrote this editorial	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
5049989	27558858	DSC	2	did the data analysis	did the data analysis	Analyzed the data	Formal analysis	YES
5049989	27558858	all authors	2	contributed to data interpretation, provided comments on the manuscript writing, and approved the final manuscript	contributed to data interpretation, provided comments on the manuscript writing, and approved the final manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
4404052	25894979	AJS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4404052	25894979	CCH	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404052	25894979	EDB	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404052	25894979	GHN	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4404052	25894979	HO	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4404052	25894979	IH	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4404052	25894979	JEH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4404052	25894979	KA	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4404052	25894979	KI	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4404052	25894979	SYL	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404052	25894979	YH	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4461736	26106622	All of the authors	2	read and approved the final version of the paper	read and approved the final version of the paper	-	-	NO
4461736	26106622	Elena Carreto-Binaghi	2	contributed equally to the design of this study|contributed equally to draft the paper|contributed equally to the development of the review	contributed equally to the design of this study	Conceived and designed the experiments	Methodology	YES
4461736	26106622	Elena Carreto-Binaghi	2	contributed equally to the design of this study|contributed equally to draft the paper|contributed equally to the development of the review	contributed equally to draft the paper	Wrote the paper	Writing - Original Draft	YES
4461736	26106622	Elena Carreto-Binaghi	2	contributed equally to the design of this study|contributed equally to draft the paper|contributed equally to the development of the review	contributed equally to the development of the review	-	-	NO
4461736	26106622	Lisandra Serra Damasceno	2	contributed equally to the design of this study|contributed equally to draft the paper|contributed equally to the development of the review	contributed equally to the design of this study	Conceived and designed the experiments	Methodology	YES
4461736	26106622	Lisandra Serra Damasceno	2	contributed equally to the design of this study|contributed equally to draft the paper|contributed equally to the development of the review	contributed equally to draft the paper	Wrote the paper	Writing - Original Draft	YES
4461736	26106622	Lisandra Serra Damasceno	2	contributed equally to the design of this study|contributed equally to draft the paper|contributed equally to the development of the review	contributed equally to the development of the review	-	-	NO
4461736	26106622	Maria Jose Soares	2	contributed with their critical opinion to improve the paper	contributed with their critical opinion to improve the paper	Wrote the paper	Writing - Review & Editing	YES
4461736	26106622	Maria Lucia Taylor	2	were supervisors of this study	were supervisors of this study	-	Supervision	YES
4461736	26106622	Maria Zancope-Oliveira	2	were supervisors of this study	were supervisors of this study	-	Supervision	YES
4461736	26106622	Marisa Fusco-Almeida	2	contributed with their critical opinion to improve the paper	contributed with their critical opinion to improve the paper	Wrote the paper	Writing - Review & Editing	YES
5217230	28056767	AGP	2	participated in the data analyses and helped draft the manuscript	participated in the data analyses and helped draft the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5217230	28056767	CS	2	participated in the experimental work and in the data analyses	participated in the experimental work and in the data analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5217230	28056767	FMA	2	participated in designing the experiment	participated in designing the experiment	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5217230	28056767	HH	2	participated in designing the experiment, and supervised the experimental work	participated in designing the experiment, and supervised the experimental work	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Supervision	YES
5217230	28056767	JA	2	conceived the experiment, carried out the experimental work, carried out the data analyses and drafted the manuscript	conceived the experiment, carried out the experimental work, carried out the data analyses and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
5217230	28056767	OL	2	participated in designing the data analysis and helped draft the manuscript	participated in designing the data analysis and helped draft the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4592561	26435727	AA	2	were involved in determining replicative fitness	were involved in determining replicative fitness	-	Validation	YES
4592561	26435727	All authors	2	were involved in the preparation of this manuscript|read and approved the final manuscript	were involved in the preparation of this manuscript	Wrote the paper	Writing - Original Draft	YES
4592561	26435727	All authors	2	were involved in the preparation of this manuscript|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4592561	26435727	DMT	2	were involved in determining replicative fitness	were involved in determining replicative fitness	-	Validation	YES
4592561	26435727	Eric J. Arts	2	has filed a patent on the chimeric virus construction and phenotypic assay used to measure co-receptor assay	has filed a patent on the chimeric virus construction and phenotypic assay used to measure co-receptor assay	Performed the experiments	Investigation	YES
4592561	26435727	FK	2	propagated the viruses	propagated the viruses	-	-	NO
4592561	26435727	GN	2	performed all of the sequence and phylogenetic analyses	performed all of the sequence and phylogenetic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4592561	26435727	ILN	2	led the studies described herein and performed the majority of the experimentation|conceived the project, supervised the research, and wrote the manuscript	led the studies described herein and performed the majority of the experimentation	Performed the experiments	Investigation	YES
4592561	26435727	ILN	2	led the studies described herein and performed the majority of the experimentation|conceived the project, supervised the research, and wrote the manuscript	conceived the project, supervised the research, and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Supervision|Writing - Original Draft	YES
4592561	26435727	OJ	2	performed the phenotypic co-receptor experiments	performed the phenotypic co-receptor experiments	Performed the experiments	Investigation	YES
4592561	26435727	RG	2	performed the phenotypic co-receptor experiments	performed the phenotypic co-receptor experiments	Performed the experiments	Investigation	YES
4344541	25724509	AA	2	developed a structure|contributed comments and edits	developed a structure	-	-	NO
4344541	25724509	AA	2	developed a structure|contributed comments and edits	contributed comments and edits	Wrote the paper	Writing - Review & Editing	YES
4344541	25724509	AK	2	contributed comments and edits	contributed comments and edits	Wrote the paper	Writing - Review & Editing	YES
4344541	25724509	EN	2	contributed comments and edits	contributed comments and edits	Wrote the paper	Writing - Review & Editing	YES
4344541	25724509	RB	2	developed a structure|wrote the original draft	developed a structure	-	-	NO
4344541	25724509	RB	2	developed a structure|wrote the original draft	wrote the original draft	Wrote the paper	Writing - Original Draft	YES
4344541	25724509	ZD	2	contributed comments and edits	contributed comments and edits	Wrote the paper	Writing - Review & Editing	YES
5078579	27614395	AT	2	collected data for this study	collected data for this study	Performed the experiments	Investigation	YES
5078579	27614395	All authors	2	contributed intellectual input to the study design and interpretation of results, and all authors reviewed the manuscript prior to submission	contributed intellectual input to the study design and interpretation of results, and all authors reviewed the manuscript prior to submission	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
5078579	27614395	FS	2	collected data for this study	collected data for this study	Performed the experiments	Investigation	YES
5078579	27614395	HI	2	collected data for this study	collected data for this study	Performed the experiments	Investigation	YES
5078579	27614395	KK	2	collected data for this study	collected data for this study	Performed the experiments	Investigation	YES
5078579	27614395	KN	2	collected data for this study	collected data for this study	Performed the experiments	Investigation	YES
5078579	27614395	KS	2	collected data for this study	collected data for this study	Performed the experiments	Investigation	YES
5078579	27614395	KT	2	collected data for this study	collected data for this study	Performed the experiments	Investigation	YES
5078579	27614395	MN	2	collected data for this study	collected data for this study	Performed the experiments	Investigation	YES
5078579	27614395	MT	2	contributed to the data analysis plan and statistical methods used	contributed to the data analysis plan and statistical methods used	Performed the experiments|Analyzed the data	Formal analysis	YES
5078579	27614395	RY	2	collected data for this study	collected data for this study	Performed the experiments	Investigation	YES
5078579	27614395	SH	2	supervised this study|approved the final manuscript for submission	supervised this study	-	Supervision	YES
5078579	27614395	SH	2	supervised this study|approved the final manuscript for submission	approved the final manuscript for submission	Wrote the paper	Writing - Review & Editing	YES
5078579	27614395	SM	2	analyzed and interpreted data and drafted the initial manuscript	analyzed and interpreted data and drafted the initial manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5078579	27614395	SY	2	collected data for this study	collected data for this study	Performed the experiments	Investigation	YES
5078579	27614395	TI	2	analyzed and interpreted data and drafted the initial manuscript	analyzed and interpreted data and drafted the initial manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5078579	27614395	TO	2	collected data for this study|collected data for this study	collected data for this study	Performed the experiments	Investigation	YES
5078579	27614395	TO	2	collected data for this study|collected data for this study	collected data for this study	Performed the experiments	Investigation	YES
5078579	27614395	YS	2	collected data for this study	collected data for this study	Performed the experiments	Investigation	YES
5078579	27614395	YW	2	collected data for this study	collected data for this study	Performed the experiments	Investigation	YES
4404053	25894552	AJS	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4404053	25894552	DY	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4404053	25894552	EC	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404053	25894552	EC	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404053	25894552	GZ	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4404053	25894552	GZ	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404053	25894552	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404053	25894552	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404053	25894552	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404053	25894552	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404053	25894552	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404053	25894552	KDG	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4404053	25894552	KDG	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404053	25894552	SR	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404053	25894552	SSR	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5504655	28744290	EK	2	designed and directed the study|carried out the study|wrote the manuscript	designed and directed the study	Conceived and designed the experiments	Methodology|Supervision	YES
5504655	28744290	EK	2	designed and directed the study|carried out the study|wrote the manuscript	carried out the study	Performed the experiments	Investigation	YES
5504655	28744290	EK	2	designed and directed the study|carried out the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5504655	28744290	OM	2	carried out the study	carried out the study	Performed the experiments	Investigation	YES
4404054	25893857	AT	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4404054	25893857	KH	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4404054	25893857	KM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404054	25893857	SY	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404054	25893857	SY	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404054	25893857	SY	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404054	25893857	YR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404054	25893857	YR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404054	25893857	YR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404054	25893857	YT	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404054	25893857	YT	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5217241	28056769	BHS	2	initiated the project and designed the experiment|wrote the manuscript	initiated the project and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5217241	28056769	BHS	2	initiated the project and designed the experiment|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5217241	28056769	CC	2	initiated the project and designed the experiment|collected the phenotypic data	initiated the project and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5217241	28056769	CC	2	initiated the project and designed the experiment|collected the phenotypic data	collected the phenotypic data	Performed the experiments	Investigation	YES
5217241	28056769	CL	2	assisted with the data analyses	assisted with the data analyses	Analyzed the data	Formal analysis	YES
5217241	28056769	HZ	2	assisted with the data analyses|wrote the manuscript	assisted with the data analyses	Analyzed the data	Formal analysis	YES
5217241	28056769	HZ	2	assisted with the data analyses|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5217241	28056769	LJL	2	performed the data analyses|wrote the manuscript	performed the data analyses	Analyzed the data	Formal analysis	YES
5217241	28056769	LJL	2	performed the data analyses|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4600939	26566435	Anders Riegels Knudsen	7	Study design, data collection, data analysis, writing, approval	Study design, data collection, data analysis, writing, approval	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology	YES
4600939	26566435	Elise Marie Okholm	7	Data collection, writing, approval	Data collection, writing, approval	Performed the experiments|Wrote the paper	Investigation	YES
4600939	26566435	Frank Viborg Mortensen	7	Study design, data analysis, writing, approval	Study design, data analysis, writing, approval	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology	YES
4600939	26566435	Holger Jon Moller	7	Study design, data analysis, writing, approval	Study design, data analysis, writing, approval	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology	YES
4600939	26566435	Jens Randel Nyengaard	7	Study design, data analysis, writing, approval	Study design, data analysis, writing, approval	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology	YES
4600939	26566435	Jonas Heilskov Graversen	7	Study design, data analysis, writing, approval	Study design, data analysis, writing, approval	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology	YES
4600939	26566435	Kasper Jarlhelt Andersen	7	Study design, data analysis, writing, approval	Study design, data analysis, writing, approval	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology	YES
4600939	26566435	Lin Nanna Okholm	7	Data collection, data analysis, writing, approval	Data collection, data analysis, writing, approval	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation	YES
4600939	26566435	Pia Svendsen	7	Data collection, data analysis, writing, approval	Data collection, data analysis, writing, approval	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation	YES
4600939	26566435	Soren Kragh Moestrup	7	Study design, writing, approval	Study design, writing, approval	Conceived and designed the experiments|Wrote the paper	Methodology	YES
4600939	26566435	Stephen Hamilton-Dutoit	7	Study design, writing, approval	Study design, writing, approval	Conceived and designed the experiments|Wrote the paper	Methodology	YES
5078585	27639823	AF	2	provided the data of the german control samples	provided the data of the german control samples	Contributed reagents/materials/analysis tools	Resources	YES
5078585	27639823	AS	2	performed data acquisition and analyses	performed data acquisition and analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5078585	27639823	BM	2	carried out functional validations	carried out functional validations	Performed the experiments	Investigation|Validation	YES
5078585	27639823	BSP	2	provided the data of the german control samples	provided the data of the german control samples	Contributed reagents/materials/analysis tools	Resources	YES
5078585	27639823	CG	2	selected the patients and provided the blood samples	selected the patients and provided the blood samples	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5078585	27639823	CS	2	selected the patients and provided the blood samples	selected the patients and provided the blood samples	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5078585	27639823	EJGB	2	created the study concept and design|selected the patients and provided the blood samples	created the study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5078585	27639823	EJGB	2	created the study concept and design|selected the patients and provided the blood samples	selected the patients and provided the blood samples	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5078585	27639823	FS	2	performed data acquisition and analyses|performed data acquisition and analyses	performed data acquisition and analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5078585	27639823	FS	2	performed data acquisition and analyses|performed data acquisition and analyses	performed data acquisition and analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5078585	27639823	HAK	2	contributed equally to this work|supervised and guided the study|wrote the manuscript	contributed equally to this work	-	-	NO
5078585	27639823	HAK	2	contributed equally to this work|supervised and guided the study|wrote the manuscript	supervised and guided the study	-	Supervision	YES
5078585	27639823	HAK	2	contributed equally to this work|supervised and guided the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5078585	27639823	KH	2	created the study concept and design	created the study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5078585	27639823	LL	2	contributed equally to this work|performed data acquisition and analyses|wrote the manuscript	contributed equally to this work	-	-	NO
5078585	27639823	LL	2	contributed equally to this work|performed data acquisition and analyses|wrote the manuscript	performed data acquisition and analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5078585	27639823	LL	2	contributed equally to this work|performed data acquisition and analyses|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5078585	27639823	LRS	2	performed data acquisition and analyses	performed data acquisition and analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5078585	27639823	MB	2	created the study concept and design	created the study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5078585	27639823	MF	2	performed data acquisition and analyses	performed data acquisition and analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5078585	27639823	MP	2	contributed equally to this work|created the study concept and design|supervised and guided the study|wrote the manuscript	contributed equally to this work	-	-	NO
5078585	27639823	MP	2	contributed equally to this work|created the study concept and design|supervised and guided the study|wrote the manuscript	created the study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5078585	27639823	MP	2	contributed equally to this work|created the study concept and design|supervised and guided the study|wrote the manuscript	supervised and guided the study	-	Supervision	YES
5078585	27639823	MP	2	contributed equally to this work|created the study concept and design|supervised and guided the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5078585	27639823	OK	2	created the study concept and design	created the study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5078585	27639823	PFZ	2	carried out functional validations	carried out functional validations	Performed the experiments	Investigation|Validation	YES
5078585	27639823	PG	2	carried out functional validations	carried out functional validations	Performed the experiments	Investigation|Validation	YES
5078585	27639823	SS	2	carried out functional validations	carried out functional validations	Performed the experiments	Investigation|Validation	YES
5078585	27639823	ST	2	contributed equally to this work|performed data acquisition and analyses|wrote the manuscript	contributed equally to this work	-	-	NO
5078585	27639823	ST	2	contributed equally to this work|performed data acquisition and analyses|wrote the manuscript	performed data acquisition and analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5078585	27639823	ST	2	contributed equally to this work|performed data acquisition and analyses|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5078585	27639823	WL	2	provided the data of the german control samples	provided the data of the german control samples	Contributed reagents/materials/analysis tools	Resources	YES
5078585	27639823	all other authors	2	participated in its finalization	participated in its finalization	-	-	NO
4344542	25724505	All authors	2	contributed equally in the preparation of this manuscript	contributed equally in the preparation of this manuscript	Wrote the paper	Writing - Original Draft	YES
4596495	26448780	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4596495	26448780	DJP	PLoS52	conceived the study|designed the study|collected data for the study|analyzed the data|drafted the initial manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4596495	26448780	DJP	PLoS52	conceived the study|designed the study|collected data for the study|analyzed the data|drafted the initial manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
4596495	26448780	DJP	PLoS52	conceived the study|designed the study|collected data for the study|analyzed the data|drafted the initial manuscript	collected data for the study	Performed the experiments	Investigation	YES
4596495	26448780	DJP	PLoS52	conceived the study|designed the study|collected data for the study|analyzed the data|drafted the initial manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
4596495	26448780	DJP	PLoS52	conceived the study|designed the study|collected data for the study|analyzed the data|drafted the initial manuscript	drafted the initial manuscript	Wrote the paper	Writing - Original Draft	YES
4596495	26448780	GM	PLoS52	conceived the study|designed the study|critically revised the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4596495	26448780	GM	PLoS52	conceived the study|designed the study|critically revised the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
4596495	26448780	GM	PLoS52	conceived the study|designed the study|critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4596495	26448780	MS	PLoS52	analyzed the data|critically revised the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
4596495	26448780	MS	PLoS52	analyzed the data|critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4596495	26448780	RJW	PLoS52	designed the study|critically revised the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
4596495	26448780	RJW	PLoS52	designed the study|critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4596495	26448780	VA	PLoS52	designed the study|collected data for the study|critically revised the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
4596495	26448780	VA	PLoS52	designed the study|collected data for the study|critically revised the manuscript	collected data for the study	Performed the experiments	Investigation	YES
4596495	26448780	VA	PLoS52	designed the study|collected data for the study|critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5504922	28744301	BJ	2	contributed to the study design	contributed to the study design	Conceived and designed the experiments	Methodology	YES
5504922	28744301	BL	2	collected and authenticated all the samples	collected and authenticated all the samples	Performed the experiments	Investigation	YES
5504922	28744301	LH	2	collected and authenticated all the samples|contributed to the study design	collected and authenticated all the samples	Performed the experiments	Investigation	YES
5504922	28744301	LH	2	collected and authenticated all the samples|contributed to the study design	contributed to the study design	Conceived and designed the experiments	Methodology	YES
5504922	28744301	LL	2	contributed to the study design|conducted the experiments|analyzed all the data and wrote the manuscript	contributed to the study design	Conceived and designed the experiments	Methodology	YES
5504922	28744301	LL	2	contributed to the study design|conducted the experiments|analyzed all the data and wrote the manuscript	conducted the experiments	Performed the experiments	Investigation	YES
5504922	28744301	LL	2	contributed to the study design|conducted the experiments|analyzed all the data and wrote the manuscript	analyzed all the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5504922	28744301	SC	2	contributed to the study design	contributed to the study design	Conceived and designed the experiments	Methodology	YES
5504922	28744301	SZ	2	contributed to the study design|conducted the experiments	contributed to the study design	Conceived and designed the experiments	Methodology	YES
5504922	28744301	SZ	2	contributed to the study design|conducted the experiments	conducted the experiments	Performed the experiments	Investigation	YES
4600940	26566439	Dr Khajehahmadi	1	Data analysis|Writing	Data analysis	Analyzed the data	Formal analysis	YES
4600940	26566439	Dr Khajehahmadi	1	Data analysis|Writing	Writing	Wrote the paper	-	YES
4600940	26566439	Dr Rahpeyma	1	Study design|Data collections	Study design	Conceived and designed the experiments	Methodology	YES
4600940	26566439	Dr Rahpeyma	1	Study design|Data collections	Data collections	Performed the experiments	Investigation	YES
4404055	25893249	EA	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404055	25893249	EA	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404055	25893249	EA	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404055	25893249	EA	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404055	25893249	EB	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404055	25893249	EB	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404055	25893249	FV	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404055	25893249	FV	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404055	25893249	GM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4404055	25893249	L. Raggi	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404055	25893249	L. Raggi	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404055	25893249	L. Raggi	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404055	25893249	L. Russi	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404055	25893249	L. Russi	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404055	25893249	L. Russi	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404055	25893249	TFS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404055	25893249	TFS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4600941	26566436	Both authors	2	contributed to idea, planning, data collection, writing the article and proof readings	contributed to idea, planning, data collection, writing the article and proof readings	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Investigation|Methodology|Resources|Writing - Original Draft	YES
4344543	25724510	AK	2	coordinated the project, conceived the study and contributed to the study design, performed all analysis and wrote the manuscript	coordinated the project, conceived the study and contributed to the study design, performed all analysis and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Project administration|Writing - Original Draft	YES
4344543	25724510	MH	2	contributed to the study design and critically revised the manuscript	contributed to the study design and critically revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
4344543	25724510	NS	2	contributed to the study design and critically revised the manuscript	contributed to the study design and critically revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5078588	27628668	BL	2	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5078588	27628668	CYL	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5078588	27628668	DC	2	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5078588	27628668	KF	2	analyzed data|prepared graphs and figures and wrote the manuscript	analyzed data	Analyzed the data	Formal analysis	YES
5078588	27628668	KF	2	analyzed data|prepared graphs and figures and wrote the manuscript	prepared graphs and figures and wrote the manuscript	Wrote the paper	Visualization|Writing - Original Draft	YES
5078588	27628668	MHX	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5078588	27628668	RA	2	performed experiments|analyzed data|prepared graphs and figures and wrote the manuscript	performed experiments	Performed the experiments	Investigation	YES
5078588	27628668	RA	2	performed experiments|analyzed data|prepared graphs and figures and wrote the manuscript	analyzed data	Analyzed the data	Formal analysis	YES
5078588	27628668	RA	2	performed experiments|analyzed data|prepared graphs and figures and wrote the manuscript	prepared graphs and figures and wrote the manuscript	Wrote the paper	Visualization|Writing - Original Draft	YES
5078588	27628668	RZ	2	established reagents used in the study	established reagents used in the study	-	-	NO
5078588	27628668	SKG	2	performed experiments|analyzed data	performed experiments	Performed the experiments	Investigation	YES
5078588	27628668	SKG	2	performed experiments|analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5078588	27628668	SV	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5078588	27628668	TB	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5078588	27628668	TLT	2	managed the patient cohort, provided patient samples and clinical data	managed the patient cohort, provided patient samples and clinical data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Investigation|Resources	YES
5078588	27628668	WX	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5078588	27628668	YSL	2	managed the patient cohort, provided patient samples and clinical data	managed the patient cohort, provided patient samples and clinical data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Investigation|Resources	YES
5078588	27628668	YXT	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5217246	28056815	AG	2	provided bioinformatics infrastructure	provided bioinformatics infrastructure	-	Formal analysis	YES
5217246	28056815	DW	2	performed genome assembly and genome annotation, respectively	performed genome assembly and genome annotation, respectively	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5217246	28056815	JB	2	performed genome assembly and genome annotation, respectively	performed genome assembly and genome annotation, respectively	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5217246	28056815	LH	2	designed the study and drafted the manuscript	designed the study and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5217246	28056815	RK	2	designed the study and drafted the manuscript	designed the study and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4642627	26566389	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4642627	26566389	JJRB	2	conceived and designed the study, and drafted manuscript	conceived and designed the study, and drafted manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
4642627	26566389	PSDS	2	conceived and designed the study, and revised manuscript for important intellectual content	conceived and designed the study, and revised manuscript for important intellectual content	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
4642627	26566389	SK-S	2	conceived and designed the study, and revised manuscript for important intellectual content	conceived and designed the study, and revised manuscript for important intellectual content	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
5506081	28747923	CZ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5506081	28747923	DZ	PLoS52	developed the population	developed the population	-	-	NO
5506081	28747923	GW	PLoS52	revised the manuscript for the language	revised the manuscript for the language	Wrote the paper	Writing - Review & Editing	YES
5506081	28747923	HH	PLoS52	designed the research work, annotated the data and drafted the manuscript	designed the research work, annotated the data and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Investigation|Methodology|Writing - Original Draft	YES
5506081	28747923	HK	PLoS52	revised the manuscript for the language	revised the manuscript for the language	Wrote the paper	Writing - Review & Editing	YES
5506081	28747923	HS	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5506081	28747923	JB	PLoS52	designed the research work, annotated the data and drafted the manuscript	designed the research work, annotated the data and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Investigation|Methodology|Writing - Original Draft	YES
5506081	28747923	JF	PLoS52	developed the population	developed the population	-	-	NO
5506081	28747923	JX	PLoS52	developed the population	developed the population	-	-	NO
5506081	28747923	LH	PLoS52	developed the population	developed the population	-	-	NO
5506081	28747923	LO	PLoS52	developed the population	developed the population	-	-	NO
5506081	28747923	NJ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5506081	28747923	QY	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5506081	28747923	SS	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5506081	28747923	XC	PLoS52	developed the population	developed the population	-	-	NO
5506081	28747923	XH	PLoS52	developed the population	developed the population	-	-	NO
5506081	28747923	XP	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5506081	28747923	XS	PLoS52	developed the population	developed the population	-	-	NO
4600942	26566438	Abdurrahim Dundar	7	data collection	data collection	Performed the experiments	Investigation	YES
4600942	26566438	Ali Toprak	7	writing	writing	Wrote the paper	-	YES
4600942	26566438	Alper Deveci	7	evaluation of X-rays	evaluation of X-rays	-	-	NO
4600942	26566438	Burak Yoldas	7	data analysis	data analysis	Analyzed the data	Formal analysis	YES
4600942	26566438	Deniz Cankaya	7	writing, study design	writing, study design	Conceived and designed the experiments|Wrote the paper	Methodology	YES
4600942	26566438	Serdar Yilmaz	7	follow-up	follow-up	-	-	NO
4600942	26566438	Yalcin Tabak	7	study design	study design	Conceived and designed the experiments	Methodology	YES
4404056	25894390	AC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4404056	25894390	AC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404056	25894390	AMC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4404056	25894390	JRN	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404056	25894390	JRN	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404056	25894390	JRN	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404056	25894390	YDT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404056	25894390	YDT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404056	25894390	YDT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404056	25894390	YDT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4344544	25724504	QAK	2	conceptualized the article	conceptualized the article	Conceived and designed the experiments	Conceptualization	YES
4344544	25724504	RD	2	conceptualized the article	conceptualized the article	Conceived and designed the experiments	Conceptualization	YES
4344544	25724504	SD	2	conceptualized the article	conceptualized the article	Conceived and designed the experiments	Conceptualization	YES
5506085	28747924	JW	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
5506085	28747924	QY	PLoS52	conceived and designed the experiments|performed research|analyzed the data|wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5506085	28747924	QY	PLoS52	conceived and designed the experiments|performed research|analyzed the data|wrote the manuscript	performed research	Performed the experiments	Investigation	YES
5506085	28747924	QY	PLoS52	conceived and designed the experiments|performed research|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5506085	28747924	QY	PLoS52	conceived and designed the experiments|performed research|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5506085	28747924	WC	PLoS52	conceived and designed the experiments|analyzed the data	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5506085	28747924	WC	PLoS52	conceived and designed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5506085	28747924	ZF	PLoS52	analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5506085	28747924	ZF	PLoS52	analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5217260	28056824	AZ	1	Drafting the manuscript for important intellectual content	Drafting the manuscript for important intellectual content	Wrote the paper	Writing - Original Draft	YES
5217260	28056824	BR	1	Data collection and analysis	Data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5217260	28056824	CJX	1	Conception and design|Data collection and analysis|Drafting the manuscript for important intellectual content	Conception and design	Conceived and designed the experiments	Conceptualization	YES
5217260	28056824	CJX	1	Conception and design|Data collection and analysis|Drafting the manuscript for important intellectual content	Data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5217260	28056824	CJX	1	Conception and design|Data collection and analysis|Drafting the manuscript for important intellectual content	Drafting the manuscript for important intellectual content	Wrote the paper	Writing - Original Draft	YES
5217260	28056824	CS	1	Data collection and analysis	Data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5217260	28056824	CW	1	Conception and design	Conception and design	Conceived and designed the experiments	Conceptualization	YES
5217260	28056824	CvD	1	Data collection and analysis	Data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5217260	28056824	DP	1	Conception and design|Drafting the manuscript for important intellectual content	Conception and design	Conceived and designed the experiments	Conceptualization	YES
5217260	28056824	DP	1	Conception and design|Drafting the manuscript for important intellectual content	Drafting the manuscript for important intellectual content	Wrote the paper	Writing - Original Draft	YES
5217260	28056824	EM	1	Conception and design|Drafting the manuscript for important intellectual content	Conception and design	Conceived and designed the experiments	Conceptualization	YES
5217260	28056824	EM	1	Conception and design|Drafting the manuscript for important intellectual content	Drafting the manuscript for important intellectual content	Wrote the paper	Writing - Original Draft	YES
5217260	28056824	GK	1	Conception and design|Drafting the manuscript for important intellectual content	Conception and design	Conceived and designed the experiments	Conceptualization	YES
5217260	28056824	GK	1	Conception and design|Drafting the manuscript for important intellectual content	Drafting the manuscript for important intellectual content	Wrote the paper	Writing - Original Draft	YES
5217260	28056824	IAM	1	Conception and design	Conception and design	Conceived and designed the experiments	Conceptualization	YES
5217260	28056824	IK	1	Data collection and analysis	Data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5217260	28056824	JB	1	Conception and design	Conception and design	Conceived and designed the experiments	Conceptualization	YES
5217260	28056824	JK	1	Data collection and analysis	Data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5217260	28056824	JMA	1	Conception and design	Conception and design	Conceived and designed the experiments	Conceptualization	YES
5217260	28056824	JS	1	Conception and design|Data collection and analysis	Conception and design	Conceived and designed the experiments	Conceptualization	YES
5217260	28056824	JS	1	Conception and design|Data collection and analysis	Data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5217260	28056824	MB	1	Data collection and analysis|Drafting the manuscript for important intellectual content	Data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5217260	28056824	MB	1	Data collection and analysis|Drafting the manuscript for important intellectual content	Drafting the manuscript for important intellectual content	Wrote the paper	Writing - Original Draft	YES
5217260	28056824	MJB	1	Data collection and analysis|Drafting the manuscript for important intellectual content	Data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5217260	28056824	MJB	1	Data collection and analysis|Drafting the manuscript for important intellectual content	Drafting the manuscript for important intellectual content	Wrote the paper	Writing - Original Draft	YES
5217260	28056824	NB	1	Data collection and analysis	Data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5217260	28056824	PvdV	1	Data collection and analysis	Data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5217260	28056824	SAJ	1	Data collection and analysis	Data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5217260	28056824	UG	1	Data collection and analysis|Drafting the manuscript for important intellectual content	Data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5217260	28056824	UG	1	Data collection and analysis|Drafting the manuscript for important intellectual content	Drafting the manuscript for important intellectual content	Wrote the paper	Writing - Original Draft	YES
5217260	28056824	YL	1	Conception and design|Drafting the manuscript for important intellectual content	Conception and design	Conceived and designed the experiments	Conceptualization	YES
5217260	28056824	YL	1	Conception and design|Drafting the manuscript for important intellectual content	Drafting the manuscript for important intellectual content	Wrote the paper	Writing - Original Draft	YES
4642676	26566390	AE	2	conducted or contributed to the data analysis|interpreted the data	conducted or contributed to the data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4642676	26566390	AE	2	conducted or contributed to the data analysis|interpreted the data	interpreted the data	Analyzed the data	Formal analysis	YES
4642676	26566390	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4642676	26566390	DE	2	conducted or contributed to the data analysis	conducted or contributed to the data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4642676	26566390	DMM	2	designed the study|conducted or contributed to the data analysis|interpreted the data|contributed to subsequent revisions	designed the study	Conceived and designed the experiments	Methodology	YES
4642676	26566390	DMM	2	designed the study|conducted or contributed to the data analysis|interpreted the data|contributed to subsequent revisions	conducted or contributed to the data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4642676	26566390	DMM	2	designed the study|conducted or contributed to the data analysis|interpreted the data|contributed to subsequent revisions	interpreted the data	Analyzed the data	Formal analysis	YES
4642676	26566390	DMM	2	designed the study|conducted or contributed to the data analysis|interpreted the data|contributed to subsequent revisions	contributed to subsequent revisions	Wrote the paper	Writing - Review & Editing	YES
4642676	26566390	ED	2	interpreted the data	interpreted the data	Analyzed the data	Formal analysis	YES
4642676	26566390	JB	2	supervised data collection of the study	supervised data collection of the study	Performed the experiments	Investigation|Supervision	YES
4642676	26566390	JW	2	supervised data collection of the study	supervised data collection of the study	Performed the experiments	Investigation|Supervision	YES
4642676	26566390	PK	2	contributed to subsequent revisions	contributed to subsequent revisions	Wrote the paper	Writing - Review & Editing	YES
4642676	26566390	PM	2	contributed to subsequent revisions	contributed to subsequent revisions	Wrote the paper	Writing - Review & Editing	YES
4642676	26566390	SO	2	designed the study|supervised data collection of the study|conducted or contributed to the data analysis|interpreted the data|prepared the original manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
4642676	26566390	SO	2	designed the study|supervised data collection of the study|conducted or contributed to the data analysis|interpreted the data|prepared the original manuscript	supervised data collection of the study	Performed the experiments	Investigation|Supervision	YES
4642676	26566390	SO	2	designed the study|supervised data collection of the study|conducted or contributed to the data analysis|interpreted the data|prepared the original manuscript	conducted or contributed to the data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4642676	26566390	SO	2	designed the study|supervised data collection of the study|conducted or contributed to the data analysis|interpreted the data|prepared the original manuscript	interpreted the data	Analyzed the data	Formal analysis	YES
4642676	26566390	SO	2	designed the study|supervised data collection of the study|conducted or contributed to the data analysis|interpreted the data|prepared the original manuscript	prepared the original manuscript	Wrote the paper	Writing - Original Draft	YES
4642676	26566390	SP	2	designed the study|collected the data	designed the study	Conceived and designed the experiments	Methodology	YES
4642676	26566390	SP	2	designed the study|collected the data	collected the data	Performed the experiments	Investigation	YES
4642676	26566390	SS	2	conducted or contributed to the data analysis|interpreted the data	conducted or contributed to the data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4642676	26566390	SS	2	conducted or contributed to the data analysis|interpreted the data	interpreted the data	Analyzed the data	Formal analysis	YES
5078627	27693104	All authors	PLoS52	edited and approved the manuscript	edited and approved the manuscript	Wrote the paper	Writing - Review & Editing	YES
5078627	27693104	B.G.	PLoS52	contributed reagents and data analysis	contributed reagents and data analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5078627	27693104	C.F.Q.	PLoS52	conceived and designed this study|analyzed the data|wrote the paper	conceived and designed this study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5078627	27693104	C.F.Q.	PLoS52	conceived and designed this study|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5078627	27693104	C.F.Q.	PLoS52	conceived and designed this study|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5078627	27693104	F.C.Z.	PLoS52	contributed reagents and data analysis	contributed reagents and data analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5078627	27693104	G.F.G.	PLoS52	contributed reagents and data analysis	contributed reagents and data analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5078627	27693104	H.F.	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5078627	27693104	H.J.W.	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5078627	27693104	H.J.W.	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5078627	27693104	H.L.D.	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5078627	27693104	H.L.D.	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5078627	27693104	H.Z.	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5078627	27693104	N.N.Z.	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5078627	27693104	P.Y.S.	PLoS52	contributed reagents and data analysis	contributed reagents and data analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5078627	27693104	Q.Y.	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5078627	27693104	S.H.S.	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5078627	27693104	W.C.C.	PLoS52	contributed reagents and data analysis	contributed reagents and data analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5078627	27693104	X.F.L.	PLoS52	conceived and designed this study|performed the experiments|analyzed the data|wrote the paper	conceived and designed this study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5078627	27693104	X.F.L.	PLoS52	conceived and designed this study|performed the experiments|analyzed the data|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5078627	27693104	X.F.L.	PLoS52	conceived and designed this study|performed the experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5078627	27693104	X.F.L.	PLoS52	conceived and designed this study|performed the experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5078627	27693104	X.P.A.	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5078627	27693104	X.Y.H.	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5078627	27693104	Y.F.Q.	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5078627	27693104	Y.G.T.	PLoS52	contributed reagents and data analysis	contributed reagents and data analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5078627	27693104	Y.Q.D.	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5078627	27693104	Y.Z.F.	PLoS52	contributed reagents and data analysis	contributed reagents and data analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5078627	27693104	Z.Y.L.	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
4602355	26568823	AE	7	conception and design of the study, interpretation of data, writing manuscript and critical review of manuscript; INM; acquisition of data, writing manuscript and review of manuscript	conception and design of the study, interpretation of data, writing manuscript and critical review of manuscript; INM; acquisition of data, writing manuscript and review of manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
4602355	26568823	AT	7	study design, acquisition of data, helped to draft manuscript and review of manuscript	study design, acquisition of data, helped to draft manuscript and review of manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
4602355	26568823	HA	7	study design, acquisition of data and critical review of manuscript	study design, acquisition of data and critical review of manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
4602355	26568823	NS	7	acquisition of data, writing manuscript and review of manuscript	acquisition of data, writing manuscript and review of manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
4348400	25735869	All authors	2	substantially contributed to the conception and drafting of the work for important intellectual content	substantially contributed to the conception and drafting of the work for important intellectual content	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4404057	25893687	BL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404057	25893687	BL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404057	25893687	BL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404057	25893687	BL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404057	25893687	BL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404057	25893687	CR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404057	25893687	CR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404057	25893687	CR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404057	25893687	CR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404057	25893687	CR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404057	25893687	EA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404057	25893687	EA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404057	25893687	EA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404057	25893687	EA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404057	25893687	EA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404057	25893687	EH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404057	25893687	EH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404057	25893687	EH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404057	25893687	EH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404057	25893687	EH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404057	25893687	GA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404057	25893687	GA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404057	25893687	GA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404057	25893687	GA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404057	25893687	GA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404057	25893687	NL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404057	25893687	NL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404057	25893687	NL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404057	25893687	NL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404057	25893687	NL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404057	25893687	SEA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404057	25893687	SEA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404057	25893687	SEA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404057	25893687	SEA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404057	25893687	SEA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404057	25893687	VK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404057	25893687	VK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404057	25893687	VK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404057	25893687	VK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404057	25893687	VK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3426785	22927895	Bernd Preininger	7	Analysis and interpretation of data, preparation of the manuscript	Analysis and interpretation of data, preparation of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3426785	22927895	Carsten Perka	7	Design of the study analysis and interpretation of data and preparation of manuscript	Design of the study analysis and interpretation of data and preparation of manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3426785	22927895	Eric Rohner	7	Analysis and interpretation of data, preparation of the manuscript	Analysis and interpretation of data, preparation of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3426785	22927895	Georg N. Duda	7	Design of the study, analysis and interpretation of data and preparation of manuscript	Design of the study, analysis and interpretation of data and preparation of manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3426785	22927895	Kristin Strohschein	7	Revision of the manuscript	Revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
3426785	22927895	Philipp von Roth	7	Design of the study, animal surgery, and preparation of the manuscript	Design of the study, animal surgery, and preparation of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
3426785	22927895	Piotr Radojewski	7	In vitro preparation of cells, muscle force measurements	In vitro preparation of cells, muscle force measurements	Performed the experiments	Investigation	YES
3426785	22927895	Tobias Winkler	7	Design of the study, animal surgery, and preparation of the manuscript	Design of the study, animal surgery, and preparation of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
4602360	26568825	Ansheng Mo	2	participated in the patient care, contributed to data collection and analysis, and helped to design and draft the manuscript	participated in the patient care, contributed to data collection and analysis, and helped to design and draft the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4602360	26568825	Jiali Zhang	2	participated in the patient care	participated in the patient care	Performed the experiments	Investigation	YES
4353835	25753933	FB	2	did research for and assisted in the preparation of the manuscript	did research for and assisted in the preparation of the manuscript	Wrote the paper	Writing - Original Draft	YES
5161419	27838479	AC	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5161419	27838479	AC	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5161419	27838479	AMFP	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
5161419	27838479	AMFP	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5161419	27838479	AMM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Collecting samples|Raised funding	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5161419	27838479	AMM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Collecting samples|Raised funding	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5161419	27838479	AMM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Collecting samples|Raised funding	Collecting samples	Performed the experiments	Investigation	YES
5161419	27838479	AMM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Collecting samples|Raised funding	Raised funding	-	Funding acquisition	YES
5161419	27838479	BHS	PLoS5	Conceived and designed the experiments|Collecting samples	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5161419	27838479	BHS	PLoS5	Conceived and designed the experiments|Collecting samples	Collecting samples	Performed the experiments	Investigation	YES
5161419	27838479	CA	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5161419	27838479	CH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5161419	27838479	CSH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Collecting samples|Raised funding	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5161419	27838479	CSH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Collecting samples|Raised funding	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5161419	27838479	CSH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Collecting samples|Raised funding	Collecting samples	Performed the experiments	Investigation	YES
5161419	27838479	CSH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Collecting samples|Raised funding	Raised funding	-	Funding acquisition	YES
5161419	27838479	CX	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5161419	27838479	DJM	PLoS5	Performed the experiments|Collecting samples	Performed the experiments	Performed the experiments	Investigation	YES
5161419	27838479	DJM	PLoS5	Performed the experiments|Collecting samples	Collecting samples	Performed the experiments	Investigation	YES
5161419	27838479	DJP	PLoS5	Conceived and designed the experiments|Collecting samples|Raised funding	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5161419	27838479	DJP	PLoS5	Conceived and designed the experiments|Collecting samples|Raised funding	Collecting samples	Performed the experiments	Investigation	YES
5161419	27838479	DJP	PLoS5	Conceived and designed the experiments|Collecting samples|Raised funding	Raised funding	-	Funding acquisition	YES
5161419	27838479	LJH	PLoS5	Conceived and designed the experiments|Collecting samples	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5161419	27838479	LJH	PLoS5	Conceived and designed the experiments|Collecting samples	Collecting samples	Performed the experiments	Investigation	YES
5161419	27838479	PN	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5161419	27838479	PN	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5161419	27838479	RN	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5161419	27838479	SP	PLoS5	Collecting samples	Collecting samples	Performed the experiments	Investigation	YES
5161419	27838479	SPH	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5161419	27838479	TKC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5161419	27838479	YNZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5161419	27838479	YNZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
5161419	27838479	YNZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4662816	26617663	AD	2	conceived the study, participated in its design and coordination and wrote the manuscript	conceived the study, participated in its design and coordination and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
4662816	26617663	AK	2	carried out the viral load assays, genotypic drug resistance testing and interpretation, and drafted the manuscript	carried out the viral load assays, genotypic drug resistance testing and interpretation, and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4662816	26617663	AS	2	conceived the study, participated in its design and coordination and wrote the manuscript	conceived the study, participated in its design and coordination and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
4662816	26617663	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4662816	26617663	DK	2	enrolled patients and collected data on patient history	enrolled patients and collected data on patient history	Performed the experiments	Investigation	YES
4662816	26617663	DN	2	enrolled patients and collected data on patient history	enrolled patients and collected data on patient history	Performed the experiments	Investigation	YES
4662816	26617663	ED	2	conceived the study, participated in its design and coordination and wrote the manuscript	conceived the study, participated in its design and coordination and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
4662816	26617663	MP	2	conceived the study, participated in its design and coordination and wrote the manuscript	conceived the study, participated in its design and coordination and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
4662816	26617663	MPD	2	conceived the study, participated in its design and coordination and wrote the manuscript	conceived the study, participated in its design and coordination and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
4662816	26617663	MS	2	conceived the study, participated in its design and coordination and wrote the manuscript	conceived the study, participated in its design and coordination and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
4662816	26617663	NV	2	carried out the viral load assays, genotypic drug resistance testing and interpretation, and drafted the manuscript	carried out the viral load assays, genotypic drug resistance testing and interpretation, and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4662816	26617663	PK	2	enrolled patients and collected data on patient history|enrolled patients and collected data on patient history	enrolled patients and collected data on patient history	Performed the experiments	Investigation	YES
4662816	26617663	PK	2	enrolled patients and collected data on patient history|enrolled patients and collected data on patient history	enrolled patients and collected data on patient history	Performed the experiments	Investigation	YES
4662816	26617663	PP	2	conceived the study, participated in its design and coordination and wrote the manuscript	conceived the study, participated in its design and coordination and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
4662816	26617663	TN	2	enrolled patients and collected data on patient history	enrolled patients and collected data on patient history	Performed the experiments	Investigation	YES
5217269	28056766	AP	PLoS52	analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5217269	28056766	AP	PLoS52	analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5217269	28056766	EM	PLoS52	conceived and designed the experiments|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5217269	28056766	EM	PLoS52	conceived and designed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5217269	28056766	TL	PLoS52	conceived and designed the experiments|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5217269	28056766	TL	PLoS52	conceived and designed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5217269	28056766	VG	PLoS52	conceived and designed the experiments|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5217269	28056766	VG	PLoS52	conceived and designed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5217269	28056766	VJ	PLoS52	analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5217269	28056766	VJ	PLoS52	analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4365104	25787347	SS	3	Strathdee	Strathdee	-	-	NO
4365104	25787347	TM	3	Mackey	Mackey	-	-	NO
4404058	25893429	GPO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404058	25893429	GPO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404058	25893429	GPO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404058	25893429	GPO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404058	25893429	HC	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404058	25893429	HC	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4404058	25893429	HJM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404058	25893429	HJM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4404058	25893429	HJM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404058	25893429	JHO	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404058	25893429	JHO	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4404058	25893429	KK	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404058	25893429	KK	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4404058	25893429	MB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404058	25893429	MB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404058	25893429	MB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404058	25893429	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404058	25893429	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4404058	25893429	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4404058	25893429	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404058	25893429	MK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404058	25893429	MK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404058	25893429	MK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404058	25893429	MK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404058	25893429	MS	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404058	25893429	MS	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4404058	25893429	RAC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404058	25893429	RAC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404058	25893429	RAC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404058	25893429	TN	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404058	25893429	TN	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4404058	25893429	TN	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4666151	26628902	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4666151	26628902	GM	2	designed the study|designed the study|conducted data analysis|drafted the manuscript which was then revised and finalized with contributions from all authors	designed the study	Conceived and designed the experiments	Methodology	YES
4666151	26628902	GM	2	designed the study|designed the study|conducted data analysis|drafted the manuscript which was then revised and finalized with contributions from all authors	designed the study	Conceived and designed the experiments	Methodology	YES
4666151	26628902	GM	2	designed the study|designed the study|conducted data analysis|drafted the manuscript which was then revised and finalized with contributions from all authors	conducted data analysis	Analyzed the data	Formal analysis	YES
4666151	26628902	GM	2	designed the study|designed the study|conducted data analysis|drafted the manuscript which was then revised and finalized with contributions from all authors	drafted the manuscript which was then revised and finalized with contributions from all authors	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4666151	26628902	LD	2	extracted and collated data for analysis|conducted data analysis	extracted and collated data for analysis	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
4666151	26628902	LD	2	extracted and collated data for analysis|conducted data analysis	conducted data analysis	Analyzed the data	Formal analysis	YES
4666151	26628902	MC	2	extracted and collated data for analysis|conducted data analysis	extracted and collated data for analysis	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
4666151	26628902	MC	2	extracted and collated data for analysis|conducted data analysis	conducted data analysis	Analyzed the data	Formal analysis	YES
4666151	26628902	MH	2	extracted and collated data for analysis|conducted data analysis	extracted and collated data for analysis	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
4666151	26628902	MH	2	extracted and collated data for analysis|conducted data analysis	conducted data analysis	Analyzed the data	Formal analysis	YES
4666151	26628902	Meintjes G. Virological	2	response to antiretroviral salvage therapy in the southern african private sector	response to antiretroviral salvage therapy in the southern african private sector	-	-	NO
4666151	26628902	RL	2	extracted and collated data for analysis	extracted and collated data for analysis	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
4666151	26628902	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
4602362	26568824	All of the authors	2	were involved in searching the literature, writing and editing this manuscript	were involved in searching the literature, writing and editing this manuscript	Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5506086	28747925	BT	PLoS52	performed the study	performed the study	Performed the experiments	Investigation	YES
5506086	28747925	CX	PLoS52	performed the study|analyzed data and performed the statistical analyses|wrote the paper	performed the study	Performed the experiments	Investigation	YES
5506086	28747925	CX	PLoS52	performed the study|analyzed data and performed the statistical analyses|wrote the paper	analyzed data and performed the statistical analyses	Analyzed the data	Formal analysis	YES
5506086	28747925	CX	PLoS52	performed the study|analyzed data and performed the statistical analyses|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5506086	28747925	JR	PLoS52	performed the study	performed the study	Performed the experiments	Investigation	YES
5506086	28747925	PW	PLoS52	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5506086	28747925	QM	PLoS52	designed the study|analyzed data and performed the statistical analyses|wrote the paper	designed the study	Conceived and designed the experiments	Methodology	YES
5506086	28747925	QM	PLoS52	designed the study|analyzed data and performed the statistical analyses|wrote the paper	analyzed data and performed the statistical analyses	Analyzed the data	Formal analysis	YES
5506086	28747925	QM	PLoS52	designed the study|analyzed data and performed the statistical analyses|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5506086	28747925	SH	PLoS52	analyzed data and performed the statistical analyses	analyzed data and performed the statistical analyses	Analyzed the data	Formal analysis	YES
5161422	27852523	AB	2	designed the study and were involved in data analysis and interpretation, as well as writing	designed the study and were involved in data analysis and interpretation, as well as writing	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology	YES
5161422	27852523	AMP	2	designed the study and were involved in data analysis and interpretation, as well as writing	designed the study and were involved in data analysis and interpretation, as well as writing	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology	YES
5161422	27852523	All authors	2	reviewed and approved the final version	reviewed and approved the final version	-	-	NO
5161422	27852523	BD	2	participated in data collection	participated in data collection	Performed the experiments	Investigation	YES
5161422	27852523	CC	2	designed the study and were involved in data analysis and interpretation, as well as writing	designed the study and were involved in data analysis and interpretation, as well as writing	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology	YES
5161422	27852523	DG	2	participated in data collection	participated in data collection	Performed the experiments	Investigation	YES
5161422	27852523	ED	2	participated in data collection	participated in data collection	Performed the experiments	Investigation	YES
5161422	27852523	JCP	2	provided statistical support for data analysis	provided statistical support for data analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5161422	27852523	MMG	2	designed the study and were involved in data analysis and interpretation, as well as writing|participated in data collection	designed the study and were involved in data analysis and interpretation, as well as writing	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology	YES
5161422	27852523	MMG	2	designed the study and were involved in data analysis and interpretation, as well as writing|participated in data collection	participated in data collection	Performed the experiments	Investigation	YES
5161422	27852523	RW	2	designed the study and were involved in data analysis and interpretation, as well as writing	designed the study and were involved in data analysis and interpretation, as well as writing	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology	YES
5217272	28056773	ESB	2	designed the mnv constructs and optimized the rna transfection protocols	designed the mnv constructs and optimized the rna transfection protocols	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5217272	28056773	VKW	2	was involved in the design of the study, data analysis, and manuscript writing	was involved in the design of the study, data analysis, and manuscript writing	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5217272	28056773	ZL	2	performed the experiments for rna seq assays, analysed the transcriptomic data, and wrote the manuscript	performed the experiments for rna seq assays, analysed the transcriptomic data, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4464002	26106606	Aida Bianco	2	collected the data and contributed to the data analysis and interpretation	collected the data and contributed to the data analysis and interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4464002	26106606	Claudia Pileggi	2	participated in the conception and design of the study, collected the data, contributed to the data analysis and interpretation, and wrote the first draft of the paper	participated in the conception and design of the study, collected the data, contributed to the data analysis and interpretation, and wrote the first draft of the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4464002	26106606	Maria Pavia	2	designed the study, was responsible for the data analysis and interpretation, and wrote the paper	designed the study, was responsible for the data analysis and interpretation, and wrote the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4464002	26106606	Valentina Mascaro	2	collected the data and contributed to the data analysis and interpretation	collected the data and contributed to the data analysis and interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4369555	25797344	The authors	2	have contributed equally to the work	have contributed equally to the work	-	-	NO
4667535	26633988	AAA	2	participated in the paper writing|participated in manuscript drafting and editing	participated in the paper writing	Wrote the paper	-	YES
4667535	26633988	AAA	2	participated in the paper writing|participated in manuscript drafting and editing	participated in manuscript drafting and editing	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4667535	26633988	All authors	2	contributed to the data analysis|read and approved the final manuscript	contributed to the data analysis	Analyzed the data	Formal analysis	YES
4667535	26633988	All authors	2	contributed to the data analysis|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4667535	26633988	GHS	2	designed the study, performed the statistical analysis, and drafted the paper	designed the study, performed the statistical analysis, and drafted the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4667535	26633988	KAA	2	participated in manuscript drafting and editing	participated in manuscript drafting and editing	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4667535	26633988	YAG	2	participated in the paper writing|participated in manuscript drafting and editing	participated in the paper writing	Wrote the paper	-	YES
4667535	26633988	YAG	2	participated in the paper writing|participated in manuscript drafting and editing	participated in manuscript drafting and editing	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4404059	25893834	CL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404059	25893834	CL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404059	25893834	CL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404059	25893834	CL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404059	25893834	CL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404059	25893834	ORZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404059	25893834	ORZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404059	25893834	ORZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404059	25893834	ORZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404059	25893834	ORZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404059	25893834	PNM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Wrote code	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404059	25893834	PNM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Wrote code	Performed the experiments	Performed the experiments	Investigation	YES
4404059	25893834	PNM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Wrote code	Analyzed the data	Analyzed the data	Formal analysis	YES
4404059	25893834	PNM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Wrote code	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404059	25893834	PNM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Wrote code	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404059	25893834	PNM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Wrote code	Wrote code	Wrote the paper	Software|Writing - Original Draft	YES
4404059	25893834	RR	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404059	25893834	RR	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5506091	28747919	AM	2	assisted in study design, participated in data collection, data analysis, and manuscript writing	assisted in study design, participated in data collection, data analysis, and manuscript writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5506091	28747919	All authors	2	gave final approval for publication	gave final approval for publication	-	-	NO
5506091	28747919	BR	2	contributed to site establishment, study design, and manuscript writing	contributed to site establishment, study design, and manuscript writing	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5506091	28747919	EdM	2	contributed to site establishment, study design, and manuscript writing	contributed to site establishment, study design, and manuscript writing	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5506091	28747919	KV	2	contributed to site establishment, study design, and manuscript writing	contributed to site establishment, study design, and manuscript writing	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5506091	28747919	MI	2	designed and coordinated the study, conducted data collection and analysis, and drafted the manuscript	designed and coordinated the study, conducted data collection and analysis, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Project administration|Writing - Original Draft	YES
5506091	28747919	OR	2	contributed to site establishment, study design, and manuscript writing	contributed to site establishment, study design, and manuscript writing	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3428671	22930667	Anne Birgitte Larsen	7	Collection of data from hvidovre hospital peter gebuhr: Coordinating and collection of data from hvidovre hospital and writing	Collection of data from hvidovre hospital peter gebuhr: Coordinating and collection of data from hvidovre hospital and writing	Performed the experiments|Wrote the paper	Investigation|Project administration	YES
3428671	22930667	Jens Sturup	7	Coordinating data collection, collection of data from Rigshospitalet and writing	Coordinating data collection, collection of data from Rigshospitalet and writing	Performed the experiments|Wrote the paper	Investigation|Project administration	YES
3428671	22930667	Karl- Erik Jensen	7	Description of radiographic technique and evaluation of ct-scans and writing	Description of radiographic technique and evaluation of ct-scans and writing	Wrote the paper	-	YES
3428671	22930667	Line Borreskov Dahl	7	Coordinating data collection, collection of data from Rigshospitalet and writing	Coordinating data collection, collection of data from Rigshospitalet and writing	Performed the experiments|Wrote the paper	Investigation|Project administration	YES
5217398	28056779	CM	2	performed dge data analysis|performed physiological and expression analysis|wrote the manuscript	performed dge data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5217398	28056779	CM	2	performed dge data analysis|performed physiological and expression analysis|wrote the manuscript	performed physiological and expression analysis	Performed the experiments	Investigation	YES
5217398	28056779	CM	2	performed dge data analysis|performed physiological and expression analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5217398	28056779	GMX	2	designed and supervised the research|wrote the manuscript	designed and supervised the research	Conceived and designed the experiments	Methodology|Supervision	YES
5217398	28056779	GMX	2	designed and supervised the research|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5217398	28056779	JLD	2	performed dge data analysis	performed dge data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5217398	28056779	KLC	2	performed physiological and expression analysis	performed physiological and expression analysis	Performed the experiments	Investigation	YES
5217398	28056779	LY	2	performed dge data analysis	performed dge data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5217398	28056779	SWL	2	designed and supervised the research|wrote the manuscript	designed and supervised the research	Conceived and designed the experiments	Methodology|Supervision	YES
5217398	28056779	SWL	2	designed and supervised the research|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5217398	28056779	TYQ	2	performed dge data analysis	performed dge data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5217398	28056779	YL	2	performed dge data analysis	performed dge data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5217398	28056779	ZYL	2	designed and supervised the research|wrote the manuscript	designed and supervised the research	Conceived and designed the experiments	Methodology|Supervision	YES
5217398	28056779	ZYL	2	designed and supervised the research|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4374084	25808633	CA	2	designed and conducted the quantitative analysis and reviewed the manuscript|have read and approved the final version	designed and conducted the quantitative analysis and reviewed the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4374084	25808633	CA	2	designed and conducted the quantitative analysis and reviewed the manuscript|have read and approved the final version	have read and approved the final version	-	-	NO
4374084	25808633	TK	2	conceptualized the paper, conducted the qualitative analysis, supervised the quantitative analysis, and wrote and reviewed the manuscript|have read and approved the final version	conceptualized the paper, conducted the qualitative analysis, supervised the quantitative analysis, and wrote and reviewed the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
4374084	25808633	TK	2	conceptualized the paper, conducted the qualitative analysis, supervised the quantitative analysis, and wrote and reviewed the manuscript|have read and approved the final version	have read and approved the final version	-	-	NO
4673723	26664457	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4673723	26664457	JA	2	carried out the patient and healthy control recruitment and flow cytometry|carried out the cmv lysate antibody elisa assay|analysed all the data and statistical analysis	carried out the patient and healthy control recruitment and flow cytometry	Performed the experiments	Investigation	YES
4673723	26664457	JA	2	carried out the patient and healthy control recruitment and flow cytometry|carried out the cmv lysate antibody elisa assay|analysed all the data and statistical analysis	carried out the cmv lysate antibody elisa assay	Performed the experiments	Investigation	YES
4673723	26664457	JA	2	carried out the patient and healthy control recruitment and flow cytometry|carried out the cmv lysate antibody elisa assay|analysed all the data and statistical analysis	analysed all the data and statistical analysis	Analyzed the data	Formal analysis	YES
4673723	26664457	JM	2	carried out the patient and healthy control recruitment and flow cytometry	carried out the patient and healthy control recruitment and flow cytometry	Performed the experiments	Investigation	YES
4673723	26664457	PP	2	analysed all the data and statistical analysis|conceived the study, participated in its design and coordinated the drafting of the manuscript	analysed all the data and statistical analysis	Analyzed the data	Formal analysis	YES
4673723	26664457	PP	2	analysed all the data and statistical analysis|conceived the study, participated in its design and coordinated the drafting of the manuscript	conceived the study, participated in its design and coordinated the drafting of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
5506182	28747920	AD	PLoS52	performed the experiments|analyzed the results and wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5506182	28747920	AD	PLoS52	performed the experiments|analyzed the results and wrote the manuscript	analyzed the results and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5506182	28747920	D-WK	PLoS52	designed the experiments|performed the experiments|analyzed the results and wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5506182	28747920	D-WK	PLoS52	designed the experiments|performed the experiments|analyzed the results and wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5506182	28747920	D-WK	PLoS52	designed the experiments|performed the experiments|analyzed the results and wrote the manuscript	analyzed the results and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5506182	28747920	JR	PLoS52	designed the experiments|analyzed the results and wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5506182	28747920	JR	PLoS52	designed the experiments|analyzed the results and wrote the manuscript	analyzed the results and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5506182	28747920	PK	PLoS52	performed the experiments|analyzed the results and wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5506182	28747920	PK	PLoS52	performed the experiments|analyzed the results and wrote the manuscript	analyzed the results and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5506182	28747920	RR	PLoS52	designed the experiments|analyzed the results and wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5506182	28747920	RR	PLoS52	designed the experiments|analyzed the results and wrote the manuscript	analyzed the results and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4404061	25893440	AZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404061	25893440	AZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404061	25893440	AZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404061	25893440	AZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404061	25893440	DK	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404061	25893440	JE	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404061	25893440	JE	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404061	25893440	JE	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404061	25893440	KK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4464846	26106613	Jia-Fen Cheng	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
4464846	26106613	Li-Ping Sun	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
4464846	26106613	Ling Wang	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
4614898	26557989	Sergio A. Acuna	7	literature review and writing	literature review and writing	Wrote the paper	Formal analysis	YES
4614898	26557989	Tyler R. Chesney	7	literature review and writing	literature review and writing	Wrote the paper	Formal analysis	YES
5217408	28061748	CMC	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5217408	28061748	LCL	PLoS52	obtained the samples and performed the experiment	obtained the samples and performed the experiment	Performed the experiments	Investigation	YES
5217408	28061748	PEL	PLoS52	conceived and wrote the manuscript	conceived and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5217408	28061748	PKN	PLoS52	obtained the samples and performed the experiment|analyzed the data|conceived and wrote the manuscript	obtained the samples and performed the experiment	Performed the experiments	Investigation	YES
5217408	28061748	PKN	PLoS52	obtained the samples and performed the experiment|analyzed the data|conceived and wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5217408	28061748	PKN	PLoS52	obtained the samples and performed the experiment|analyzed the data|conceived and wrote the manuscript	conceived and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5217408	28061748	SML	PLoS52	conceived and wrote the manuscript	conceived and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5217408	28061748	TWP	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
4380906	25828269	AG	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
4380906	25828269	All authors	2	contributed to writing the article, revising the manuscript and have given the final approval of this version to be published	contributed to writing the article, revising the manuscript and have given the final approval of this version to be published	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4380906	25828269	BE	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
4380906	25828269	BT	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
4380906	25828269	CB	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
4380906	25828269	CF	2	designed the study|did the analysis of the data	designed the study	Conceived and designed the experiments	Methodology	YES
4380906	25828269	CF	2	designed the study|did the analysis of the data	did the analysis of the data	Analyzed the data	Formal analysis	YES
4380906	25828269	DT	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
4380906	25828269	JH	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
4380906	25828269	JO	2	designed the study|coordinated the study|did the analysis of the data	designed the study	Conceived and designed the experiments	Methodology	YES
4380906	25828269	JO	2	designed the study|coordinated the study|did the analysis of the data	coordinated the study	-	Project administration	YES
4380906	25828269	JO	2	designed the study|coordinated the study|did the analysis of the data	did the analysis of the data	Analyzed the data	Formal analysis	YES
4380906	25828269	MC	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
4380906	25828269	MTS	2	did the analysis of the data	did the analysis of the data	Analyzed the data	Formal analysis	YES
4380906	25828269	RH	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
4380906	25828269	SG	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
4380906	25828269	SW	2	coordinated the study	coordinated the study	-	Project administration	YES
5506190	28747922	FC	2	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5506190	28747922	JG	2	designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
5506190	28747922	JK	2	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5506190	28747922	SL	2	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5506190	28747922	TZ	2	conceived the research|designed the research|revised the paper	conceived the research	Conceived and designed the experiments	Conceptualization	YES
5506190	28747922	TZ	2	conceived the research|designed the research|revised the paper	designed the research	Conceived and designed the experiments	Methodology	YES
5506190	28747922	TZ	2	conceived the research|designed the research|revised the paper	revised the paper	Wrote the paper	Writing - Review & Editing	YES
5506190	28747922	YC	2	performed the experiments and analyzed the data|drafted the manuscript	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5506190	28747922	YC	2	performed the experiments and analyzed the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5506190	28747922	ZW	2	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4404091	25894532	AH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404091	25894532	AH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404091	25894532	AH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404091	25894532	DH	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404091	25894532	DH	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404091	25894532	DH	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404091	25894532	DH	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404091	25894532	MR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404091	25894532	MR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404091	25894532	MR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404091	25894532	MR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404091	25894532	MR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4676091	26692884	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4676091	26692884	FM	2	collected data, performed analysis, interpretation of data and drafted the manuscript	collected data, performed analysis, interpretation of data and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4676091	26692884	JPV	2	contributed substantially to the conception and design of study|were involved with the interpretation and presentation of data, and the critical review of the manuscript	contributed substantially to the conception and design of study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4676091	26692884	JPV	2	contributed substantially to the conception and design of study|were involved with the interpretation and presentation of data, and the critical review of the manuscript	were involved with the interpretation and presentation of data, and the critical review of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4676091	26692884	MA	2	contributed substantially to the conception and design of study|were involved with the interpretation and presentation of data, and the critical review of the manuscript	contributed substantially to the conception and design of study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4676091	26692884	MA	2	contributed substantially to the conception and design of study|were involved with the interpretation and presentation of data, and the critical review of the manuscript	were involved with the interpretation and presentation of data, and the critical review of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4676091	26692884	RC	2	were involved with the interpretation and presentation of data, and the critical review of the manuscript	were involved with the interpretation and presentation of data, and the critical review of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5161446	27908611	B.C.	2	performed in imaging	performed in imaging	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
5161446	27908611	C.L.X.	2	participated in the animal surgeries and carried out animal care	participated in the animal surgeries and carried out animal care	Performed the experiments	Investigation	YES
5161446	27908611	J.H.L.	2	assisted with optogenetics and contributed experimental suggestions	assisted with optogenetics and contributed experimental suggestions	Performed the experiments	Investigation	YES
5161446	27908611	S.H.Z.	2	assisted with statistical analyses and in vivo electrophysiological recordings	assisted with statistical analyses and in vivo electrophysiological recordings	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5161446	27908611	S.M.D.	2	assisted with optogenetics and contributed experimental suggestions	assisted with optogenetics and contributed experimental suggestions	Performed the experiments	Investigation	YES
5161446	27908611	S.W.	2	assisted with statistical analyses and in vivo electrophysiological recordings	assisted with statistical analyses and in vivo electrophysiological recordings	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5161446	27908611	W.W.H.	2	performed in imaging	performed in imaging	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
5161446	27908611	X.H.W.	2	conducted the learning & memory studies	conducted the learning & memory studies	Performed the experiments	Investigation	YES
5161446	27908611	Y.G.	2	assisted with statistical analyses and in vivo electrophysiological recordings	assisted with statistical analyses and in vivo electrophysiological recordings	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5161446	27908611	Y.W.	2	performed most of the experiment, acquired most of the data presented, and performed the statistical analyses|participated in the animal surgeries and carried out animal care|conducted the learning & memory studies	performed most of the experiment, acquired most of the data presented, and performed the statistical analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5161446	27908611	Y.W.	2	performed most of the experiment, acquired most of the data presented, and performed the statistical analyses|participated in the animal surgeries and carried out animal care|conducted the learning & memory studies	participated in the animal surgeries and carried out animal care	Performed the experiments	Investigation	YES
5161446	27908611	Y.W.	2	performed most of the experiment, acquired most of the data presented, and performed the statistical analyses|participated in the animal surgeries and carried out animal care|conducted the learning & memory studies	conducted the learning & memory studies	Performed the experiments	Investigation	YES
5161446	27908611	Z.C.	2	designed experiments and co-wrote the manuscript	designed experiments and co-wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5161446	27908611	Z.H.X.	2	designed experiments and co-wrote the manuscript|performed most of the experiment, acquired most of the data presented, and performed the statistical analyses	designed experiments and co-wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5161446	27908611	Z.H.X.	2	designed experiments and co-wrote the manuscript|performed most of the experiment, acquired most of the data presented, and performed the statistical analyses	performed most of the experiment, acquired most of the data presented, and performed the statistical analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5161446	27908611	Z.X.N.	2	performed in imaging	performed in imaging	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
5217421	28056792	All authors	2	reviewed and approved this submission	reviewed and approved this submission	-	-	NO
5217421	28056792	XC	2	conceived the experiment	conceived the experiment	Conceived and designed the experiments	Conceptualization	YES
5217421	28056792	XQ	2	conceived the experiment|performed the research|analyzed the data and wrote the manuscript	conceived the experiment	Conceived and designed the experiments	Conceptualization	YES
5217421	28056792	XQ	2	conceived the experiment|performed the research|analyzed the data and wrote the manuscript	performed the research	Performed the experiments	Investigation	YES
5217421	28056792	XQ	2	conceived the experiment|performed the research|analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5217421	28056792	XX	2	performed the research|collected the data|analyzed the data and wrote the manuscript	performed the research	Performed the experiments	Investigation	YES
5217421	28056792	XX	2	performed the research|collected the data|analyzed the data and wrote the manuscript	collected the data	Performed the experiments	Investigation	YES
5217421	28056792	XX	2	performed the research|collected the data|analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5217421	28056792	YS	2	collected the data	collected the data	Performed the experiments	Investigation	YES
5785760	29337543	A.d.S.	2	contributed equally	contributed equally	-	-	NO
5785760	29337543	B.F.	2	contributed equally	contributed equally	-	-	NO
4393416	25862565	The author	2	was involved in the revision of the manuscript contents and has given final approval of this version to be published|was involved in the revision of the manuscript contents and has given final approval of this version to be published|was involved in the revision of the manuscript contents and has given final approval of this version to be published|was involved in drafting the manuscript and revising it for content and has given final approval of this version to be published|was involved in the revision of the manuscript contents and has given final approval of this version to be published	was involved in the revision of the manuscript contents and has given final approval of this version to be published	Wrote the paper	Writing - Review & Editing	YES
4393416	25862565	The author	2	was involved in the revision of the manuscript contents and has given final approval of this version to be published|was involved in the revision of the manuscript contents and has given final approval of this version to be published|was involved in the revision of the manuscript contents and has given final approval of this version to be published|was involved in drafting the manuscript and revising it for content and has given final approval of this version to be published|was involved in the revision of the manuscript contents and has given final approval of this version to be published	was involved in the revision of the manuscript contents and has given final approval of this version to be published	Wrote the paper	Writing - Review & Editing	YES
4393416	25862565	The author	2	was involved in the revision of the manuscript contents and has given final approval of this version to be published|was involved in the revision of the manuscript contents and has given final approval of this version to be published|was involved in the revision of the manuscript contents and has given final approval of this version to be published|was involved in drafting the manuscript and revising it for content and has given final approval of this version to be published|was involved in the revision of the manuscript contents and has given final approval of this version to be published	was involved in the revision of the manuscript contents and has given final approval of this version to be published	Wrote the paper	Writing - Review & Editing	YES
4393416	25862565	The author	2	was involved in the revision of the manuscript contents and has given final approval of this version to be published|was involved in the revision of the manuscript contents and has given final approval of this version to be published|was involved in the revision of the manuscript contents and has given final approval of this version to be published|was involved in drafting the manuscript and revising it for content and has given final approval of this version to be published|was involved in the revision of the manuscript contents and has given final approval of this version to be published	was involved in drafting the manuscript and revising it for content and has given final approval of this version to be published	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4393416	25862565	The author	2	was involved in the revision of the manuscript contents and has given final approval of this version to be published|was involved in the revision of the manuscript contents and has given final approval of this version to be published|was involved in the revision of the manuscript contents and has given final approval of this version to be published|was involved in drafting the manuscript and revising it for content and has given final approval of this version to be published|was involved in the revision of the manuscript contents and has given final approval of this version to be published	was involved in the revision of the manuscript contents and has given final approval of this version to be published	Wrote the paper	Writing - Review & Editing	YES
4624565	26587233	CPRP	2	performed the surgery	performed the surgery	Performed the experiments	Investigation	YES
4624565	26587233	JCG	2	writed and translated the paper	writed and translated the paper	Wrote the paper	Writing - Original Draft	YES
4624565	26587233	JJSS	2	performed the surgery|writed and translated the paper	performed the surgery	Performed the experiments	Investigation	YES
4624565	26587233	JJSS	2	performed the surgery|writed and translated the paper	writed and translated the paper	Wrote the paper	Writing - Original Draft	YES
4624565	26587233	JPR	2	revised the whole work	revised the whole work	Wrote the paper	Writing - Review & Editing	YES
4624565	26587233	JRR	2	writed and translated the paper	writed and translated the paper	Wrote the paper	Writing - Original Draft	YES
4404093	25894293	AB	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404093	25894293	AB	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404093	25894293	KSHP	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404093	25894293	KSHP	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404093	25894293	KSHP	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404093	25894293	KSHP	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404093	25894293	LJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404093	25894293	LJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404093	25894293	LJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404093	25894293	LJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404093	25894293	LJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404093	25894293	MAM	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404093	25894293	PJB	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404093	25894293	PJB	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404093	25894293	RBB	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404093	25894293	RBB	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404093	25894293	RBB	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404093	25894293	RBB	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404093	25894293	RHF	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404093	25894293	RHF	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404093	25894293	RHF	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404093	25894293	RHF	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4696135	26719752	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4696135	26719752	Grant Programme	2	that provided financial support to our operating expenses for this study	that provided financial support to our operating expenses for this study	Performed the experiments	Funding acquisition|Investigation	YES
4696135	26719752	KD	2	performed the initial physical examination of the children and contributed to the write up of the manuscript|performed the follow-up physical examination of the children, assisted with data analysis and contributed to the write-up of the manuscript	performed the initial physical examination of the children and contributed to the write up of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4696135	26719752	KD	2	performed the initial physical examination of the children and contributed to the write up of the manuscript|performed the follow-up physical examination of the children, assisted with data analysis and contributed to the write-up of the manuscript	performed the follow-up physical examination of the children, assisted with data analysis and contributed to the write-up of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4696135	26719752	KW	2	performed the initial physical examination of the children and contributed to the write up of the manuscript	performed the initial physical examination of the children and contributed to the write up of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4696135	26719752	TM	2	arranged the follow-up physical examinations, collected and analyzed the follow-up data and was the primary author of the manuscript	arranged the follow-up physical examinations, collected and analyzed the follow-up data and was the primary author of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5233807	27939425	AS	CRediT	Resources|Writing - review & editing	Resources	Contributed reagents/materials/analysis tools	Resources	YES
5233807	27939425	AS	CRediT	Resources|Writing - review & editing	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
5233807	27939425	BP	CRediT	Writing - review & editing	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
5233807	27939425	JL	CRediT	Writing - review & editing	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
5233807	27939425	KA	CRediT	Data curation|Writing - review & editing|Project administration	Data curation	Analyzed the data	Data curation	YES
5233807	27939425	KA	CRediT	Data curation|Writing - review & editing|Project administration	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
5233807	27939425	KA	CRediT	Data curation|Writing - review & editing|Project administration	Project administration	-	Project administration	YES
5233807	27939425	KW	CRediT	Conceptualization|Methodology|Validation|Writing - original draft|Writing - review & editing|Visualization|Supervision|Funding acquisition	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
5233807	27939425	KW	CRediT	Conceptualization|Methodology|Validation|Writing - original draft|Writing - review & editing|Visualization|Supervision|Funding acquisition	Methodology	Performed the experiments	Methodology	YES
5233807	27939425	KW	CRediT	Conceptualization|Methodology|Validation|Writing - original draft|Writing - review & editing|Visualization|Supervision|Funding acquisition	Validation	Performed the experiments	Validation	YES
5233807	27939425	KW	CRediT	Conceptualization|Methodology|Validation|Writing - original draft|Writing - review & editing|Visualization|Supervision|Funding acquisition	Writing - original draft	Wrote the paper	Writing - Original Draft	YES
5233807	27939425	KW	CRediT	Conceptualization|Methodology|Validation|Writing - original draft|Writing - review & editing|Visualization|Supervision|Funding acquisition	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
5233807	27939425	KW	CRediT	Conceptualization|Methodology|Validation|Writing - original draft|Writing - review & editing|Visualization|Supervision|Funding acquisition	Visualization	Analyzed the data	Visualization	YES
5233807	27939425	KW	CRediT	Conceptualization|Methodology|Validation|Writing - original draft|Writing - review & editing|Visualization|Supervision|Funding acquisition	Supervision	-	Supervision	YES
5233807	27939425	KW	CRediT	Conceptualization|Methodology|Validation|Writing - original draft|Writing - review & editing|Visualization|Supervision|Funding acquisition	Funding acquisition	-	Funding acquisition	YES
5233807	27939425	MM	CRediT	Data curation|Writing - original draft|Writing - review & editing|Visualization|Project administration	Data curation	Analyzed the data	Data curation	YES
5233807	27939425	MM	CRediT	Data curation|Writing - original draft|Writing - review & editing|Visualization|Project administration	Writing - original draft	Wrote the paper	Writing - Original Draft	YES
5233807	27939425	MM	CRediT	Data curation|Writing - original draft|Writing - review & editing|Visualization|Project administration	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
5233807	27939425	MM	CRediT	Data curation|Writing - original draft|Writing - review & editing|Visualization|Project administration	Visualization	Analyzed the data	Visualization	YES
5233807	27939425	MM	CRediT	Data curation|Writing - original draft|Writing - review & editing|Visualization|Project administration	Project administration	-	Project administration	YES
5233807	27939425	MW	CRediT	Resources|Writing - review & editing	Resources	Contributed reagents/materials/analysis tools	Resources	YES
5233807	27939425	MW	CRediT	Resources|Writing - review & editing	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
5233807	27939425	PC	CRediT	Resources|Writing - review & editing	Resources	Contributed reagents/materials/analysis tools	Resources	YES
5233807	27939425	PC	CRediT	Resources|Writing - review & editing	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
5233807	27939425	SH	CRediT	Methodology|Validation|Formal analysis|Writing - review & editing|Funding acquisition	Methodology	Performed the experiments	Methodology	YES
5233807	27939425	SH	CRediT	Methodology|Validation|Formal analysis|Writing - review & editing|Funding acquisition	Validation	Performed the experiments	Validation	YES
5233807	27939425	SH	CRediT	Methodology|Validation|Formal analysis|Writing - review & editing|Funding acquisition	Formal analysis	Analyzed the data	Formal analysis	YES
5233807	27939425	SH	CRediT	Methodology|Validation|Formal analysis|Writing - review & editing|Funding acquisition	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
5233807	27939425	SH	CRediT	Methodology|Validation|Formal analysis|Writing - review & editing|Funding acquisition	Funding acquisition	-	Funding acquisition	YES
5506204	28747921	HR	PLoS52	performed the experiments|analyzed the data|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5506204	28747921	HR	PLoS52	performed the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5506204	28747921	HR	PLoS52	performed the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5506204	28747921	LN	PLoS52	conceived and designed the experiments|wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5506204	28747921	LN	PLoS52	conceived and designed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5506204	28747921	PA	PLoS52	conceived and designed the experiments|analyzed the data|wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5506204	28747921	PA	PLoS52	conceived and designed the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5506204	28747921	PA	PLoS52	conceived and designed the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5506204	28747921	PO	PLoS52	conceived and designed the experiments|wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5506204	28747921	PO	PLoS52	conceived and designed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3434701	22962568	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
3434701	22962568	BAM	2	designed or performed dorsal root ganglion immunostaining and methods for analysis	designed or performed dorsal root ganglion immunostaining and methods for analysis	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3434701	22962568	JLH	2	acquired and analyzed data for cerebral spinal fluid biomarkers	acquired and analyzed data for cerebral spinal fluid biomarkers	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3434701	22962568	KDA	2	designed, performed and analyzed the study of gait in these animals	designed, performed and analyzed the study of gait in these animals	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
3434701	22962568	LAS	2	designed or performed the midbrain pain receptor immunostaining and methods for analysis|contributed to study design and funding, and supervised the study at all levels, oversaw data analysis and finalized the manuscript	designed or performed the midbrain pain receptor immunostaining and methods for analysis	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3434701	22962568	LAS	2	designed or performed the midbrain pain receptor immunostaining and methods for analysis|contributed to study design and funding, and supervised the study at all levels, oversaw data analysis and finalized the manuscript	contributed to study design and funding, and supervised the study at all levels, oversaw data analysis and finalized the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Funding acquisition|Methodology|Resources|Supervision|Writing - Review & Editing	YES
3434701	22962568	LJ	2	designed or performed dorsal root ganglion immunostaining and methods for analysis	designed or performed dorsal root ganglion immunostaining and methods for analysis	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3434701	22962568	MAG	2	designed or performed dorsal root ganglion immunostaining and methods for analysis|in the completion of animal surgeries	designed or performed dorsal root ganglion immunostaining and methods for analysis	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3434701	22962568	MAG	2	designed or performed dorsal root ganglion immunostaining and methods for analysis|in the completion of animal surgeries	in the completion of animal surgeries	Performed the experiments	Investigation	YES
3434701	22962568	MFS	2	designed or performed the midbrain pain receptor immunostaining and methods for analysis	designed or performed the midbrain pain receptor immunostaining and methods for analysis	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3434701	22962568	PYH	2	designed or performed the midbrain pain receptor immunostaining and methods for analysis|designed or performed dorsal root ganglion immunostaining and methods for analysis	designed or performed the midbrain pain receptor immunostaining and methods for analysis	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3434701	22962568	PYH	2	designed or performed the midbrain pain receptor immunostaining and methods for analysis|designed or performed dorsal root ganglion immunostaining and methods for analysis	designed or performed dorsal root ganglion immunostaining and methods for analysis	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3434701	22962568	VBK	2	acquired and analyzed data for cerebral spinal fluid biomarkers	acquired and analyzed data for cerebral spinal fluid biomarkers	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5217437	28056800	FRV	2	conceived and designed the experiment|wrote the manuscript	conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5217437	28056800	FRV	2	conceived and designed the experiment|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5217437	28056800	MLP	2	conceived and designed the experiment|wrote the manuscript	conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5217437	28056800	MLP	2	conceived and designed the experiment|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3504400	23213304	S. Ye	2	contributed equally to this study	contributed equally to this study	-	-	NO
3504400	23213304	Y. Cao	2	contributed equally to this study	contributed equally to this study	-	-	NO
3504400	23213304	Y. Huang	2	contributed equally to this study	contributed equally to this study	-	-	NO
4404094	25894763	DRB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4404094	25894763	DRB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404094	25894763	HJP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404094	25894763	HJP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404094	25894763	HJP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404094	25894763	JR	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404094	25894763	JR	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404094	25894763	JR	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404094	25894763	MJD	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404094	25894763	MJD	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404094	25894763	MJD	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404094	25894763	MJD	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404094	25894763	MP	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404094	25894763	MP	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404094	25894763	MP	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404094	25894763	MP	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404094	25894763	RB	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4404094	25894763	RB	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4404094	25894763	SA	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4404094	25894763	SA	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4404094	25894763	SFB	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404094	25894763	SVB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404094	25894763	SVB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404094	25894763	SVB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404094	25894763	SVB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404094	25894763	VA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404094	25894763	VA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404094	25894763	VA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404094	25894763	VA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404094	25894763	VA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4394156	25865372	Coffs Harbour	1	Wales	Wales	-	-	NO
4394156	25865372	D Ellis	1	Wales	Wales	-	-	NO
4394156	25865372	General Medical Practice	1	Wales	Wales	-	-	NO
4394156	25865372	North Fitzroy	1	Victoria	Victoria	-	-	NO
4394156	25865372	Northside Clinic	1	Victoria	Victoria	-	-	NO
4394156	25865372	P Locke	1	Victoria	Victoria	-	-	NO
4394156	25865372	R Liddle	1	Victoria	Victoria	-	-	NO
4394156	25865372	R Moore	1	Victoria	Victoria	-	-	NO
4394156	25865372	S Edwards	1	Victoria	Victoria	-	-	NO
4624569	26587229	Anton Cheng	7	Study concept	Study concept	Conceived and designed the experiments	Conceptualization	YES
4624569	26587229	David Tan	7	Study concept	Study concept	Conceived and designed the experiments	Conceptualization	YES
4624569	26587229	Dr Sundaraamoorthy	7	Study design	Study design	Conceived and designed the experiments	Methodology	YES
4624569	26587229	Eugene Lim	7	Study concept, data collection, writing the paper	Study concept, data collection, writing the paper	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
4624569	26587229	RS	7	Study design	Study design	Conceived and designed the experiments	Methodology	YES
4624569	26587229	Tan Tzu-Jen	7	Study concept	Study concept	Conceived and designed the experiments	Conceptualization	YES
4624569	26587229	Teh Hui Seong	7	Study concept	Study concept	Conceived and designed the experiments	Conceptualization	YES
4465649	26114109	Alberto Schanaider	2	conceived, designed, and supervised the study, analysed the results, and revised the paper	conceived, designed, and supervised the study, analysed the results, and revised the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Supervision|Writing - Review & Editing	YES
4465649	26114109	Andre Antonio Monteiro	2	conceived, designed, and supervised the study, analysed the results, and revised the paper	conceived, designed, and supervised the study, analysed the results, and revised the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Supervision|Writing - Review & Editing	YES
4465649	26114109	Antonio Carlos Pires	2	supervised the magnetic resonance imaging exam and drafted the paper	supervised the magnetic resonance imaging exam and drafted the paper	Analyzed the data|Wrote the paper	Supervision|Visualization|Writing - Original Draft	YES
4465649	26114109	Fabio Ribeiro Guedes	2	supervised the radiological exam	supervised the radiological exam	-	Supervision	YES
4465649	26114109	Luz Barbosa	2	conceived and designed the restraining device, performed the anesthesia, realized all the procedures with the rabbits, and also drafted the paper	conceived and designed the restraining device, performed the anesthesia, realized all the procedures with the rabbits, and also drafted the paper	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
4465649	26114109	Sergio Augusto Lopes	2	supervised the scintigraphy exam and drafted the paper	supervised the scintigraphy exam and drafted the paper	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Original Draft	YES
4465649	26114109	Silva Machado	2	helped with the procedures with the rabbit	helped with the procedures with the rabbit	Performed the experiments	Investigation	YES
4700595	26734067	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4700595	26734067	HIV	2	immunoassays and contributed to portions of the manuscript	immunoassays and contributed to portions of the manuscript	Performed the experiments	Investigation	YES
4700595	26734067	PJ	2	participated in study design, care of patients, and drafting of the manuscript	participated in study design, care of patients, and drafting of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
4700595	26734067	PL	2	was the lead author and participated in data collection and drafting of the manuscript	was the lead author and participated in data collection and drafting of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4700595	26734067	SH	2	conceived the study, cared for patients, and edited the manuscript	conceived the study, cared for patients, and edited the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Review & Editing	YES
4700595	26734067	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5233814	27932296	DS	2	designed the research, analyzed the data, and wrote the paper	designed the research, analyzed the data, and wrote the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5233814	27932296	GW	2	helped design and perform experiments	helped design and perform experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5233814	27932296	LM	2	designed the research, analyzed the data, and wrote the paper	designed the research, analyzed the data, and wrote the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5233814	27932296	Y-JL	2	generated ppard hi daudi cells	generated ppard hi daudi cells	Performed the experiments	Investigation	YES
5233814	27932296	YS	2	helped design and perform experiments	helped design and perform experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5506325	28747918	CaE	2	cyst nematodes	cyst nematodes	-	-	NO
5506325	28747918	ChE	2	gus analysis	gus analysis	-	-	NO
5506325	28747918	JC	2	cyst nematodes	cyst nematodes	-	-	NO
5506325	28747918	RO	2	cyst nematodes	cyst nematodes	-	-	NO
5506325	28747918	ReS	2	gus analysis, qrt pcr	gus analysis, qrt pcr	Performed the experiments	Investigation	YES
5506325	28747918	RyS	2	se for ngs	se for ngs	-	-	NO
5506325	28747918	SN	2	se for ngs	se for ngs	-	-	NO
5506325	28747918	SS	2	writing, arabidopsis, and rkn	writing, arabidopsis, and rkn	Wrote the paper	-	YES
5506325	28747918	TD	2	ngs analysis	ngs analysis	-	-	NO
5506325	28747918	TI	2	writing, se for ngs, arabidopsis, and rkn	writing, se for ngs, arabidopsis, and rkn	Wrote the paper	-	YES
5506325	28747918	TK	2	se for ngs	se for ngs	-	-	NO
5506325	28747918	TO	2	se for ngs	se for ngs	-	-	NO
5506325	28747918	TS	2	histological analysis	histological analysis	Performed the experiments	Investigation	YES
5506325	28747918	YA	2	se for ngs	se for ngs	-	-	NO
5506325	28747918	YY	2	ngs analysis	ngs analysis	-	-	NO
4624570	26587228	IK	2	were involved in the conception, design and interpretation|collected data, reviewed relevant published reports and provided the images	were involved in the conception, design and interpretation	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
4624570	26587228	IK	2	were involved in the conception, design and interpretation|collected data, reviewed relevant published reports and provided the images	collected data, reviewed relevant published reports and provided the images	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
4624570	26587228	SM	2	were involved in the conception, design and interpretation|wrote the manuscript|collected data, reviewed relevant published reports and provided the images	were involved in the conception, design and interpretation	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
4624570	26587228	SM	2	were involved in the conception, design and interpretation|wrote the manuscript|collected data, reviewed relevant published reports and provided the images	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4624570	26587228	SM	2	were involved in the conception, design and interpretation|wrote the manuscript|collected data, reviewed relevant published reports and provided the images	collected data, reviewed relevant published reports and provided the images	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
4624570	26587228	ST	2	were involved in the conception, design and interpretation|wrote the manuscript|collected data, reviewed relevant published reports and provided the images	were involved in the conception, design and interpretation	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
4624570	26587228	ST	2	were involved in the conception, design and interpretation|wrote the manuscript|collected data, reviewed relevant published reports and provided the images	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4624570	26587228	ST	2	were involved in the conception, design and interpretation|wrote the manuscript|collected data, reviewed relevant published reports and provided the images	collected data, reviewed relevant published reports and provided the images	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
4624570	26587228	TD	2	were involved in the conception, design and interpretation|wrote the manuscript	were involved in the conception, design and interpretation	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
4624570	26587228	TD	2	were involved in the conception, design and interpretation|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5217548	28056770	DR	2	helped conceive the study, participated in its design and coordination, carried out data analysis and drafted the manuscript	helped conceive the study, participated in its design and coordination, carried out data analysis and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Project administration|Writing - Original Draft	YES
5217548	28056770	LH	2	critically revised the manuscript and generated the nirs data	critically revised the manuscript and generated the nirs data	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5217548	28056770	RB	2	assisted in field design and phenotyping, and critically revised the manuscript	assisted in field design and phenotyping, and critically revised the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5217548	28056770	SB	2	critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5217548	28056770	SK	2	helped conceive the study, participated in its design and coordination, and critically revised the manuscript	helped conceive the study, participated in its design and coordination, and critically revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Review & Editing	YES
5217548	28056770	TH	2	critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5217548	28056770	WR	2	critically revised the manuscript and generated the nirs data	critically revised the manuscript and generated the nirs data	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5217548	28056770	ZB	2	assisted in field design and phenotyping, and critically revised the manuscript	assisted in field design and phenotyping, and critically revised the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4404097	25893973	XMH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4404097	25893973	XQL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4404097	25893973	XQL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404097	25893973	XTL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404097	25893973	XTL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404097	25893973	XTL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404097	25893973	XTL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404097	25893973	XYQ	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4637338	26635955	Ana Maria Minaya	7	design of the paper, draft and review of literature	design of the paper, draft and review of literature	Conceived and designed the experiments|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4637338	26635955	Fernando Mendoza Moreno	7	review of literature	review of literature	-	Formal analysis	YES
4637338	26635955	Fernando Noguerales Fraguas	7	review of the paper	review of the paper	Wrote the paper	Writing - Review & Editing	YES
4637338	26635955	Javier Granell	7	review of the paper	review of the paper	Wrote the paper	Writing - Review & Editing	YES
4637338	26635955	Julio Cesar Garcia	7	search of bibliography and translation	search of bibliography and translation	Performed the experiments	Formal analysis|Investigation	YES
5507953	28751897	ICARDA	5	supported this research in India	supported this research in India	-	-	NO
4704295	26744599	AH	2	provided corrections to study plan and manuscript	provided corrections to study plan and manuscript	Wrote the paper	Writing - Review & Editing	YES
4704295	26744599	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4704295	26744599	EFB	2	provided corrections to study plan and manuscript	provided corrections to study plan and manuscript	Wrote the paper	Writing - Review & Editing	YES
4704295	26744599	ES	2	provided corrections to study plan and manuscript	provided corrections to study plan and manuscript	Wrote the paper	Writing - Review & Editing	YES
4704295	26744599	JDK	2	prepared study plan, carried out the statistical analyses and drafted the manuscript	prepared study plan, carried out the statistical analyses and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4704295	26744599	JK	2	provided corrections to study plan and manuscript	provided corrections to study plan and manuscript	Wrote the paper	Writing - Review & Editing	YES
4704295	26744599	PP	2	provided corrections to study plan and manuscript	provided corrections to study plan and manuscript	Wrote the paper	Writing - Review & Editing	YES
5233817	27965105	DC	2	completed the full text screening	completed the full text screening	Performed the experiments	Investigation	YES
5233817	27965105	MV	2	critically appraised the protocol, manuscript and also contributed to its development by revising different versions	critically appraised the protocol, manuscript and also contributed to its development by revising different versions	Conceived and designed the experiments	Methodology	YES
5233817	27965105	NM	2	critically appraised the protocol, manuscript and also contributed to its development by revising different versions	critically appraised the protocol, manuscript and also contributed to its development by revising different versions	Conceived and designed the experiments	Methodology	YES
5233817	27965105	NR	2	assisted with the database searches and ran the updated searches	assisted with the database searches and ran the updated searches	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5233817	27965105	OE	2	wrote the manuscript|conceived the initial idea for the study|screened all abstracts|completed the full text screening	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5233817	27965105	OE	2	wrote the manuscript|conceived the initial idea for the study|screened all abstracts|completed the full text screening	conceived the initial idea for the study	Conceived and designed the experiments	Conceptualization	YES
5233817	27965105	OE	2	wrote the manuscript|conceived the initial idea for the study|screened all abstracts|completed the full text screening	screened all abstracts	Performed the experiments	Investigation	YES
5233817	27965105	OE	2	wrote the manuscript|conceived the initial idea for the study|screened all abstracts|completed the full text screening	completed the full text screening	Performed the experiments	Investigation	YES
5233817	27965105	OvH	2	screened all abstracts	screened all abstracts	Performed the experiments	Investigation	YES
5233817	27965105	RP	2	critically appraised the protocol, manuscript and also contributed to its development by revising different versions	critically appraised the protocol, manuscript and also contributed to its development by revising different versions	Conceived and designed the experiments	Methodology	YES
5233817	27965105	TF	2	critically appraised the protocol, manuscript and also contributed to its development by revising different versions	critically appraised the protocol, manuscript and also contributed to its development by revising different versions	Conceived and designed the experiments	Methodology	YES
5217551	28056762	AT	2	designed and implemented the pipeline|wrote the manuscript	designed and implemented the pipeline	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5217551	28056762	AT	2	designed and implemented the pipeline|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5217551	28056762	CL	2	performed computational analyses, generated figures and implemented certain wrapper scripts|wrote the manuscript	performed computational analyses, generated figures and implemented certain wrapper scripts	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Software|Visualization	YES
5217551	28056762	CL	2	performed computational analyses, generated figures and implemented certain wrapper scripts|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5217551	28056762	IA	2	offered biological insights and helped with the interpretation of hi-c data	offered biological insights and helped with the interpretation of hi-c data	Analyzed the data	Formal analysis	YES
5217551	28056762	PN	2	offered biological insights and helped with the interpretation of hi-c data	offered biological insights and helped with the interpretation of hi-c data	Analyzed the data	Formal analysis	YES
5217551	28056762	SK	2	wrote the user manual	wrote the user manual	Wrote the paper	Writing - Original Draft	YES
4465651	26114104	G. G. Chrisanfova	2	equally contributed to the study	equally contributed to the study	-	-	NO
4465651	26114104	S. K. Semyenova	2	equally contributed to the study	equally contributed to the study	-	-	NO
4719209	26793264	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4719209	26793264	ECK	2	supervised data collection and participated in writing of the manuscript	supervised data collection and participated in writing of the manuscript	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Original Draft	YES
4719209	26793264	EK	2	participated in monitoring data collection, participated in data analysis and writing of the manuscript	participated in monitoring data collection, participated in data analysis and writing of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Supervision|Writing - Original Draft	YES
4719209	26793264	FM	2	participated in study design, data analysis and reviewed the manuscript	participated in study design, data analysis and reviewed the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
4719209	26793264	I. The	2	funders had no role in the conduct of the study and writing of the manuscript	funders had no role in the conduct of the study and writing of the manuscript	Performed the experiments|Wrote the paper	Funding acquisition|Investigation|Writing - Original Draft	YES
4719209	26793264	KM	2	were in charge of the procedures for the hiv testing, participated in field supervision, and reviewed the manuscript	were in charge of the procedures for the hiv testing, participated in field supervision, and reviewed the manuscript	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Review & Editing	YES
4719209	26793264	LM	2	were in charge of the procedures for the hiv testing, participated in field supervision, and reviewed the manuscript	were in charge of the procedures for the hiv testing, participated in field supervision, and reviewed the manuscript	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Review & Editing	YES
4719209	26793264	NK	2	conceptualised the study, led study design, data collection, analysis and drafted the manuscript	conceptualised the study, led study design, data collection, analysis and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4719209	26793264	PCK	2	conceptualised the study, led study design, data collection, analysis and drafted the manuscript	conceptualised the study, led study design, data collection, analysis and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4719209	26793264	PM	2	supervised data collection and participated in writing of the manuscript	supervised data collection and participated in writing of the manuscript	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Original Draft	YES
4719209	26793264	TBCARE	2	funders had no role in the conduct of the study and writing of the manuscript	funders had no role in the conduct of the study and writing of the manuscript	Performed the experiments|Wrote the paper	Funding acquisition|Investigation|Writing - Original Draft	YES
4719209	26793264	WN	2	participated in monitoring data collection, participated in data analysis and writing of the manuscript	participated in monitoring data collection, participated in data analysis and writing of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Supervision|Writing - Original Draft	YES
5507954	28751904	LH	2	assisted manuscript writing and editing	assisted manuscript writing and editing	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5507954	28751904	SQ	2	analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5507954	28751904	WF	2	conceivedand designed the research|analyzed the data and wrote the manuscript	conceivedand designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5507954	28751904	WF	2	conceivedand designed the research|analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5507954	28751904	WL	2	provided data and data acquisition capacity	provided data and data acquisition capacity	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5507954	28751904	XL	2	conceivedand designed the research	conceivedand designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5507954	28751904	YH	2	provided data and data acquisition capacity	provided data and data acquisition capacity	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5507954	28751904	YW	2	provided data and data acquisition capacity	provided data and data acquisition capacity	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5507954	28751904	YZ	2	provided data and data acquisition capacity	provided data and data acquisition capacity	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
3504405	23213296	Xiao-Wu Chen	2	contributed equally to this work	contributed equally to this work	-	-	NO
3504405	23213296	Yuan Ming Di	2	contributed equally to this work	contributed equally to this work	-	-	NO
4404098	25894917	CL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404098	25894917	CL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404098	25894917	CL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404098	25894917	CZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404098	25894917	CZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404098	25894917	CZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404098	25894917	CZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404098	25894917	FG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4404098	25894917	FG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404098	25894917	HW	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404098	25894917	HW	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404098	25894917	HW	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404098	25894917	JC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4404098	25894917	JC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404098	25894917	LY	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404098	25894917	TY	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404098	25894917	WM	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404098	25894917	XW	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4404098	25894917	XW	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4410128	25912181	GR	2	was one of the chief investigators of the study and was involved in designing the study|formulated the research question|interpreted the results and drafted the manuscript	was one of the chief investigators of the study and was involved in designing the study	Conceived and designed the experiments	Methodology	YES
4410128	25912181	GR	2	was one of the chief investigators of the study and was involved in designing the study|formulated the research question|interpreted the results and drafted the manuscript	formulated the research question	Conceived and designed the experiments	Conceptualization	YES
4410128	25912181	GR	2	was one of the chief investigators of the study and was involved in designing the study|formulated the research question|interpreted the results and drafted the manuscript	interpreted the results and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4410128	25912181	HW	2	formulated the research question|performed the statistical analysis|interpreted the results and drafted the manuscript	formulated the research question	Conceived and designed the experiments	Conceptualization	YES
4410128	25912181	HW	2	formulated the research question|performed the statistical analysis|interpreted the results and drafted the manuscript	performed the statistical analysis	Analyzed the data	Formal analysis	YES
4410128	25912181	HW	2	formulated the research question|performed the statistical analysis|interpreted the results and drafted the manuscript	interpreted the results and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5217569	28056787	FM	1	Contribution of reagents/materials/analysis tools	Contribution of reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5217569	28056787	HS	1	Conception and design of experiments|Analysis and interpretation of data|Drafting and revising the manuscript	Conception and design of experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5217569	28056787	HS	1	Conception and design of experiments|Analysis and interpretation of data|Drafting and revising the manuscript	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
5217569	28056787	HS	1	Conception and design of experiments|Analysis and interpretation of data|Drafting and revising the manuscript	Drafting and revising the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5217569	28056787	HT	1	Conception and design of experiments|Analysis and interpretation of data|Drafting and revising the manuscript	Conception and design of experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5217569	28056787	HT	1	Conception and design of experiments|Analysis and interpretation of data|Drafting and revising the manuscript	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
5217569	28056787	HT	1	Conception and design of experiments|Analysis and interpretation of data|Drafting and revising the manuscript	Drafting and revising the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5217569	28056787	KH	1	Contribution of reagents/materials/analysis tools	Contribution of reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5217569	28056787	KI	1	Contribution of reagents/materials/analysis tools	Contribution of reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5217569	28056787	KS	1	Conducting the experiments	Conducting the experiments	Performed the experiments	Investigation	YES
5217569	28056787	M. Saitou	1	Contribution of reagents/materials/analysis tools	Contribution of reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5217569	28056787	M. Suyama	1	Contribution of reagents/materials/analysis tools	Contribution of reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5217569	28056787	NK	1	Conducting the experiments	Conducting the experiments	Performed the experiments	Investigation	YES
5217569	28056787	TI	1	Contribution of reagents/materials/analysis tools	Contribution of reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5233820	27974246	H.K.	PLoS52	conceived the study|supervised the study|wrote the paper	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5233820	27974246	H.K.	PLoS52	conceived the study|supervised the study|wrote the paper	supervised the study	-	Supervision	YES
5233820	27974246	H.K.	PLoS52	conceived the study|supervised the study|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5233820	27974246	H.T.	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5233820	27974246	J.G.	PLoS52	contributed to the interpretation of the data	contributed to the interpretation of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5233820	27974246	J.I.	PLoS52	contributed to the interpretation of the data	contributed to the interpretation of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5233820	27974246	K.K.	PLoS52	contributed to the interpretation of the data	contributed to the interpretation of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5233820	27974246	K.T.	PLoS52	contributed to the interpretation of the data	contributed to the interpretation of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5233820	27974246	K.U.	PLoS52	contributed to the interpretation of the data	contributed to the interpretation of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5233820	27974246	S.H.	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5233820	27974246	S.K.	PLoS52	contributed to the interpretation of the data	contributed to the interpretation of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5233820	27974246	S.S.	PLoS52	contributed to the interpretation of the data	contributed to the interpretation of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5233820	27974246	S.T.	PLoS52	performed the experiments|conceived the study|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5233820	27974246	S.T.	PLoS52	performed the experiments|conceived the study|wrote the paper	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5233820	27974246	S.T.	PLoS52	performed the experiments|conceived the study|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5233820	27974246	T.S.	PLoS52	contributed to the interpretation of the data	contributed to the interpretation of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5233820	27974246	T.Y.	PLoS52	performed the experiments|conceived the study|supervised the study|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5233820	27974246	T.Y.	PLoS52	performed the experiments|conceived the study|supervised the study|wrote the paper	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5233820	27974246	T.Y.	PLoS52	performed the experiments|conceived the study|supervised the study|wrote the paper	supervised the study	-	Supervision	YES
5233820	27974246	T.Y.	PLoS52	performed the experiments|conceived the study|supervised the study|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5233820	27974246	Y.A.	PLoS52	contributed to the interpretation of the data	contributed to the interpretation of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5233820	27974246	Y.C.	PLoS52	contributed to the interpretation of the data	contributed to the interpretation of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5233820	27974246	Y.M.	PLoS52	contributed to the interpretation of the data	contributed to the interpretation of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5233820	27974246	Y.S.	PLoS52	contributed to the interpretation of the data	contributed to the interpretation of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5844650	29420889	A.O.	2	contributed equally to this work	contributed equally to this work	-	-	NO
5844650	29420889	D.H.	2	contributed equally to this work	contributed equally to this work	-	-	NO
5844650	29420889	SS	2	contributed equally to this work	contributed equally to this work	-	-	NO
4404099	25893675	CG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404099	25893675	CG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404099	25893675	CG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404099	25893675	CG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404099	25893675	CG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404099	25893675	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404099	25893675	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404099	25893675	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404099	25893675	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404099	25893675	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404099	25893675	MF	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404099	25893675	MF	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404099	25893675	MF	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404099	25893675	MF	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4465652	26114117	Abdulaziz Abdullah Alqarawi	2	supervised all the stages and provided comments on the draft	supervised all the stages and provided comments on the draft	Wrote the paper	Supervision|Writing - Original Draft	YES
4465652	26114117	Akash Tariq	2	designed the research study|conducted the field work|organized and analyzed the data and wrote the whole paper	designed the research study	Conceived and designed the experiments	Methodology	YES
4465652	26114117	Akash Tariq	2	designed the research study|conducted the field work|organized and analyzed the data and wrote the whole paper	conducted the field work	Performed the experiments	Investigation	YES
4465652	26114117	Akash Tariq	2	designed the research study|conducted the field work|organized and analyzed the data and wrote the whole paper	organized and analyzed the data and wrote the whole paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4465652	26114117	Muhammad Adnan	2	designed the research study	designed the research study	Conceived and designed the experiments	Methodology	YES
4465652	26114117	Riaz Ullah	2	conducted the field work	conducted the field work	Performed the experiments	Investigation	YES
4465652	26114117	Sakina Mussarat	2	conducted the field work|organized and analyzed the data and wrote the whole paper	conducted the field work	Performed the experiments	Investigation	YES
4465652	26114117	Sakina Mussarat	2	conducted the field work|organized and analyzed the data and wrote the whole paper	organized and analyzed the data and wrote the whole paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4719214	26793265	Both authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4719214	26793265	HMS	2	prepared the original manuscript and contributed to subsequent revisions	prepared the original manuscript and contributed to subsequent revisions	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4719214	26793265	JDK	2	prepared the original manuscript and contributed to subsequent revisions	prepared the original manuscript and contributed to subsequent revisions	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5264269	27765642	ACL	PLoS5	Contributed to meg data collection	Contributed to meg data collection	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5264269	27765642	APG	PLoS5	Contributed to study design|Contributed to data analysis|Wrote the paper	Contributed to study design	Conceived and designed the experiments	Methodology	YES
5264269	27765642	APG	PLoS5	Contributed to study design|Contributed to data analysis|Wrote the paper	Contributed to data analysis	Analyzed the data	Formal analysis	YES
5264269	27765642	APG	PLoS5	Contributed to study design|Contributed to data analysis|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5264269	27765642	All	PLoS5	Contributed to editing the paper	Contributed to editing the paper	Wrote the paper	Writing - Review & Editing	YES
5264269	27765642	BEE	PLoS5	Contributed to general data collection and clinical evaluation|Contributed to study design	Contributed to general data collection and clinical evaluation	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5264269	27765642	BEE	PLoS5	Contributed to general data collection and clinical evaluation|Contributed to study design	Contributed to study design	Conceived and designed the experiments	Methodology	YES
5264269	27765642	LMJ	PLoS5	Contributed to general data collection and clinical evaluation|Contributed to study design|Contributed to data analysis|Wrote the paper	Contributed to general data collection and clinical evaluation	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5264269	27765642	LMJ	PLoS5	Contributed to general data collection and clinical evaluation|Contributed to study design|Contributed to data analysis|Wrote the paper	Contributed to study design	Conceived and designed the experiments	Methodology	YES
5264269	27765642	LMJ	PLoS5	Contributed to general data collection and clinical evaluation|Contributed to study design|Contributed to data analysis|Wrote the paper	Contributed to data analysis	Analyzed the data	Formal analysis	YES
5264269	27765642	LMJ	PLoS5	Contributed to general data collection and clinical evaluation|Contributed to study design|Contributed to data analysis|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4425809	25956171	FVG	2	designed and developed the study	designed and developed the study	Conceived and designed the experiments	Methodology	YES
4425809	25956171	JA	2	designed and developed the study	designed and developed the study	Conceived and designed the experiments	Methodology	YES
4425809	25956171	JHK	2	designed and developed the study	designed and developed the study	Conceived and designed the experiments	Methodology	YES
4425809	25956171	JLKF	2	conducted the study	conducted the study	Performed the experiments	Investigation	YES
4425809	25956171	NC	2	conducted the study	conducted the study	Performed the experiments	Investigation	YES
4425809	25956171	NM	2	designed and developed the study	designed and developed the study	Conceived and designed the experiments	Methodology	YES
4425809	25956171	NP	2	designed and developed the study|conducted the study|drafted the manuscript	designed and developed the study	Conceived and designed the experiments	Methodology	YES
4425809	25956171	NP	2	designed and developed the study|conducted the study|drafted the manuscript	conducted the study	Performed the experiments	Investigation	YES
4425809	25956171	NP	2	designed and developed the study|conducted the study|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4425809	25956171	NT	2	conducted the study	conducted the study	Performed the experiments	Investigation	YES
4425809	25956171	PP	2	designed and developed the study	designed and developed the study	Conceived and designed the experiments	Methodology	YES
4425809	25956171	RP	2	conducted the study	conducted the study	Performed the experiments	Investigation	YES
4425809	25956171	RT	2	designed and developed the study	designed and developed the study	Conceived and designed the experiments	Methodology	YES
4425809	25956171	SP	2	designed and developed the study|conducted the study|performed all of the statistical analysis	designed and developed the study	Conceived and designed the experiments	Methodology	YES
4425809	25956171	SP	2	designed and developed the study|conducted the study|performed all of the statistical analysis	conducted the study	Performed the experiments	Investigation	YES
4425809	25956171	SP	2	designed and developed the study|conducted the study|performed all of the statistical analysis	performed all of the statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5507956	28751900	D-WL	PLoS52	performed the experiments|analyzed the data|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5507956	28751900	D-WL	PLoS52	performed the experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5507956	28751900	D-WL	PLoS52	performed the experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5507956	28751900	E-HK	PLoS52	performed the experiments|analyzed the data|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5507956	28751900	E-HK	PLoS52	performed the experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5507956	28751900	E-HK	PLoS52	performed the experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5507956	28751900	HUK	PLoS52	analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5507956	28751900	HUK	PLoS52	analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5507956	28751900	J-SJ	PLoS52	analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5507956	28751900	J-SJ	PLoS52	analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5507956	28751900	K-RL	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5507956	28751900	K-RL	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5507956	28751900	S-JJ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5217624	28056777	BF	2	performed the statistical analysis, and participated in the design of the study, the transcriptome analysis and wrote part of manuscript	performed the statistical analysis, and participated in the design of the study, the transcriptome analysis and wrote part of manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5217624	28056777	YD	2	proposed the project, designed the whole study, wrote and finalized the manuscript	proposed the project, designed the whole study, wrote and finalized the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5217624	28056777	YH	2	participated in the design of the study and revised the early manuscript	participated in the design of the study and revised the early manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5507963	28751896	AL	2	are employed by waters corporation	are employed by waters corporation	-	-	NO
5507963	28751896	All authors	2	revised the manuscript critically and approved the final version for publication	revised the manuscript critically and approved the final version for publication	Wrote the paper	Writing - Review & Editing	YES
5507963	28751896	BW	2	are employed by waters corporation	are employed by waters corporation	-	-	NO
5507963	28751896	FL	2	conceived of this study and designed the experiments|prepared samples for proteome and metabolite profiling|analyzed and interpreted the data|drafted the manuscript	conceived of this study and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5507963	28751896	FL	2	conceived of this study and designed the experiments|prepared samples for proteome and metabolite profiling|analyzed and interpreted the data|drafted the manuscript	prepared samples for proteome and metabolite profiling	Performed the experiments	Investigation	YES
5507963	28751896	FL	2	conceived of this study and designed the experiments|prepared samples for proteome and metabolite profiling|analyzed and interpreted the data|drafted the manuscript	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5507963	28751896	FL	2	conceived of this study and designed the experiments|prepared samples for proteome and metabolite profiling|analyzed and interpreted the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5507963	28751896	HO	2	are employed by waters corporation	are employed by waters corporation	-	-	NO
5507963	28751896	KZ	2	analyzed and interpreted the data	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5507963	28751896	LB	2	conceived of this study and designed the experiments|drafted the manuscript	conceived of this study and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5507963	28751896	LB	2	conceived of this study and designed the experiments|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5507963	28751896	MS	2	for metabolite profiling	for metabolite profiling	Performed the experiments	Investigation	YES
5507963	28751896	PT	2	conceived of this study and designed the experiments|prepared samples for proteome and metabolite profiling	conceived of this study and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5507963	28751896	PT	2	conceived of this study and designed the experiments|prepared samples for proteome and metabolite profiling	prepared samples for proteome and metabolite profiling	Performed the experiments	Investigation	YES
5507963	28751896	The other authors	2	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	Performed the experiments	Investigation	YES
4660275	26693276	Araya Gebreyesus Wasihun	2	prepared the manuscript for publication	prepared the manuscript for publication	Wrote the paper	Writing - Original Draft	YES
4660275	26693276	Kibrom Gebresilasie	2	did the patient management and write literature reviews	did the patient management and write literature reviews	Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4660275	26693276	Weldehawaria Weldu	2	did the patient management and write literature reviews	did the patient management and write literature reviews	Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4438085	25990095	The authors	2	contributed equally to the work	contributed equally to the work	-	-	NO
3474948	23091578	HK	2	analyzed and interpreted all patient data and was major contributor in writing the manuscript	analyzed and interpreted all patient data and was major contributor in writing the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3474948	23091578	IS	2	was involved in revising the manuscript critically for important intellectual content	was involved in revising the manuscript critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4404100	25893243	ACV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404100	25893243	ACV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404100	25893243	ACV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404100	25893243	ACV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404100	25893243	ACV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404100	25893243	CR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404100	25893243	CR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404100	25893243	CR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404100	25893243	CR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404100	25893243	IAV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404100	25893243	IAV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404100	25893243	IAV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404100	25893243	IAV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404100	25893243	IAV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404100	25893243	JAC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404100	25893243	JAC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404100	25893243	JAC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404100	25893243	JAC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5217627	28056763	HT	2	designed software, developed statistical methodology, performed data analysis, and drafted the manuscript	designed software, developed statistical methodology, performed data analysis, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Software|Writing - Original Draft	YES
5217627	28056763	JM	2	conceived the study, supervised research, and assisted in development of the methodology, data analysis, and drafting the manuscript	conceived the study, supervised research, and assisted in development of the methodology, data analysis, and drafting the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Supervision|Writing - Original Draft	YES
5217627	28056763	PDS	2	developed the statistical methodology, supervised research, and assisted in drafting the manuscript	developed the statistical methodology, supervised research, and assisted in drafting the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Supervision|Writing - Original Draft	YES
4719688	26793263	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4719688	26793263	CN	2	carried out the statistical analyses	carried out the statistical analyses	Analyzed the data	Formal analysis	YES
4719688	26793263	CZ	2	implemented the study, analyzed the results and drafted the manuscript	implemented the study, analyzed the results and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4719688	26793263	HZ	2	contributed to the acquisition of the data and revising the manuscript critically	contributed to the acquisition of the data and revising the manuscript critically	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Resources|Writing - Review & Editing	YES
4719688	26793263	WW	2	carried out the statistical analyses	carried out the statistical analyses	Analyzed the data	Formal analysis	YES
4719688	26793263	XL	2	implemented the study, analyzed the results and drafted the manuscript|carried out the statistical analyses|completed the sample collection and the cd4 cell counts	implemented the study, analyzed the results and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4719688	26793263	XL	2	implemented the study, analyzed the results and drafted the manuscript|carried out the statistical analyses|completed the sample collection and the cd4 cell counts	carried out the statistical analyses	Analyzed the data	Formal analysis	YES
4719688	26793263	XL	2	implemented the study, analyzed the results and drafted the manuscript|carried out the statistical analyses|completed the sample collection and the cd4 cell counts	completed the sample collection and the cd4 cell counts	Performed the experiments	Investigation	YES
4719688	26793263	YZ	2	contributed to the acquisition of the data and revising the manuscript critically	contributed to the acquisition of the data and revising the manuscript critically	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Resources|Writing - Review & Editing	YES
4680082	26740874	All authors	2	revised the manuscript and approved it for submission	revised the manuscript and approved it for submission	Wrote the paper	Writing - Review & Editing	YES
5264349	27810309	L.C.	2	planned and performed experiments and wrote the manuscript|performed molecular experiments|performed in vivo experiments|performed inhibitor experiments	planned and performed experiments and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
5264349	27810309	L.C.	2	planned and performed experiments and wrote the manuscript|performed molecular experiments|performed in vivo experiments|performed inhibitor experiments	performed molecular experiments	Performed the experiments	Investigation	YES
5264349	27810309	L.C.	2	planned and performed experiments and wrote the manuscript|performed molecular experiments|performed in vivo experiments|performed inhibitor experiments	performed in vivo experiments	Performed the experiments	Investigation	YES
5264349	27810309	L.C.	2	planned and performed experiments and wrote the manuscript|performed molecular experiments|performed in vivo experiments|performed inhibitor experiments	performed inhibitor experiments	Performed the experiments	Investigation	YES
5264349	27810309	M.D.	2	performed inhibitor experiments	performed inhibitor experiments	Performed the experiments	Investigation	YES
5264349	27810309	R.S.	2	performed molecular experiments	performed molecular experiments	Performed the experiments	Investigation	YES
5264349	27810309	S.M.	2	provided reagent	provided reagent	Contributed reagents/materials/analysis tools	Resources	YES
5264349	27810309	S.U.	2	the former principal investigator, oversaw the project	the former principal investigator, oversaw the project	Conceived and designed the experiments	Conceptualization|Funding acquisition|Supervision	YES
5264349	27810309	T.I.	2	helped design experiments, reviewed the manuscript, and conceived the scientific ideas and edited the manuscript	helped design experiments, reviewed the manuscript, and conceived the scientific ideas and edited the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Writing - Review & Editing	YES
5264349	27810309	T.K.	2	performed in vivo experiments|performed inhibitor experiments	performed in vivo experiments	Performed the experiments	Investigation	YES
5264349	27810309	T.K.	2	performed in vivo experiments|performed inhibitor experiments	performed inhibitor experiments	Performed the experiments	Investigation	YES
4440874	25997453	AAM	2	participated in the study concept, design, statistical analysis, and drafting of the manuscript	participated in the study concept, design, statistical analysis, and drafting of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
4440874	25997453	AD	2	participated in the drafting of manuscript and performed a critical revision for intellectual content	participated in the drafting of manuscript and performed a critical revision for intellectual content	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
4440874	25997453	AG	2	participated in the drafting of manuscript and performed a critical revision for intellectual content	participated in the drafting of manuscript and performed a critical revision for intellectual content	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
4440874	25997453	IPS	2	participated in the study concept, design, and drafting of the manuscript	participated in the study concept, design, and drafting of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
4440874	25997453	SR	2	conceived of the study, participated in its design and coordination, and helped to draft the manuscript	conceived of the study, participated in its design and coordination, and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
4465655	26114099	Chia-Yu Chang	2	conceived the design and the coordination of study|carried out animal studies and biotechnological assays	conceived the design and the coordination of study	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
4465655	26114099	Chia-Yu Chang	2	conceived the design and the coordination of study|carried out animal studies and biotechnological assays	carried out animal studies and biotechnological assays	Performed the experiments	Investigation	YES
4465655	26114099	How-Ran Guo	2	performed the statistical analysis in data	performed the statistical analysis in data	Analyzed the data	Formal analysis	YES
4465655	26114099	Jiunn-Jye Chuu	2	drafted the paper|contributed equally to this work	drafted the paper	Wrote the paper	Writing - Original Draft	YES
4465655	26114099	Jiunn-Jye Chuu	2	drafted the paper|contributed equally to this work	contributed equally to this work	-	-	NO
4465655	26114099	Li-Chuan Lin	2	carried out animal studies and biotechnological assays	carried out animal studies and biotechnological assays	Performed the experiments	Investigation	YES
4465655	26114099	Tain-Junn Cheng	2	contributed equally to this work	contributed equally to this work	-	-	NO
4465655	26114099	Wan-Chen Tsai	2	carried out animal studies and biotechnological assays	carried out animal studies and biotechnological assays	Performed the experiments	Investigation	YES
4680629	26793313	Ai Sadatomo	2	is correspoding author, analyzed and collected data, drafted of the article	is correspoding author, analyzed and collected data, drafted of the article	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4680629	26793313	Dr Horie	2	approved of the article	approved of the article	-	-	NO
4680629	26793313	Dr Sata	2	approved of the article	approved of the article	-	-	NO
4680630	26793310	Hidetaka Uramoto	2	carried out the operations and revision of the manuscript	carried out the operations and revision of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4680630	26793310	Hirohiko Akiyama	2	have contributed to the clinical management of the patient	have contributed to the clinical management of the patient	Performed the experiments	Investigation	YES
4680630	26793310	Hiroshi Sakai	2	have contributed to the clinical management of the patient	have contributed to the clinical management of the patient	Performed the experiments	Investigation	YES
4680630	26793310	Hiroyasu Kinoshita	2	carried out the operations	carried out the operations	Performed the experiments	Investigation	YES
4680630	26793310	Maiko Atari	2	carried out the operations	carried out the operations	Performed the experiments	Investigation	YES
4680630	26793310	Mitsuro Fukuhara	2	carried out the operations	carried out the operations	Performed the experiments	Investigation	YES
4680630	26793310	Yoshihiro Saito	2	carried out the radiotherapy	carried out the radiotherapy	Performed the experiments	Investigation	YES
4680630	26793310	Yuki Nakajima	2	carried out the operations and wrote the manuscript	carried out the operations and wrote the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4442125	26004637	AL	2	have parcipated to the data collection|have written the paper	have parcipated to the data collection	Performed the experiments	Investigation	YES
4442125	26004637	AL	2	have parcipated to the data collection|have written the paper	have written the paper	Wrote the paper	Writing - Original Draft	YES
4442125	26004637	AT	2	have parcipated to the data collection	have parcipated to the data collection	Performed the experiments	Investigation	YES
4442125	26004637	All authors	2	have designed the study	have designed the study	Conceived and designed the experiments	Methodology	YES
4442125	26004637	CTK	2	have parcipated to the data collection	have parcipated to the data collection	Performed the experiments	Investigation	YES
4442125	26004637	IB	2	have parcipated to the data collection	have parcipated to the data collection	Performed the experiments	Investigation	YES
4442125	26004637	JT	2	have parcipated to the data collection	have parcipated to the data collection	Performed the experiments	Investigation	YES
4442125	26004637	KL	2	have written the paper	have written the paper	Wrote the paper	Writing - Original Draft	YES
4442125	26004637	MM	2	have parcipated to the data collection	have parcipated to the data collection	Performed the experiments	Investigation	YES
4442125	26004637	ON	2	have parcipated to the data collection	have parcipated to the data collection	Performed the experiments	Investigation	YES
4442125	26004637	all authors	2	have revised and amended the paper	have revised and amended the paper	Wrote the paper	Writing - Review & Editing	YES
5507967	28751901	HZ	2	performed the experiments and participated to the data analysis	performed the experiments and participated to the data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5507967	28751901	RJ	2	projected design and supervision	projected design and supervision	Conceived and designed the experiments	Methodology|Supervision	YES
5507967	28751901	XM	2	performed the qrt-pcr experiments	performed the qrt-pcr experiments	Performed the experiments	Investigation	YES
5217656	28056804	AK	PLoS52	collected samples	collected samples	Performed the experiments	Investigation	YES
5217656	28056804	AYHL	PLoS52	collected samples	collected samples	Performed the experiments	Investigation	YES
5217656	28056804	CHA	PLoS52	analyzed the data|developed the bioinformatics software and drafted the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5217656	28056804	CHA	PLoS52	analyzed the data|developed the bioinformatics software and drafted the manuscript	developed the bioinformatics software and drafted the manuscript	Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Software|Writing - Original Draft	YES
5217656	28056804	ESKM	PLoS52	conceived the study|collected samples|analyzed the data	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5217656	28056804	ESKM	PLoS52	conceived the study|collected samples|analyzed the data	collected samples	Performed the experiments	Investigation	YES
5217656	28056804	ESKM	PLoS52	conceived the study|collected samples|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5217656	28056804	TLC	PLoS52	conceived the study|analyzed the data	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5217656	28056804	TLC	PLoS52	conceived the study|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
4404101	25894557	A. Niimi	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4404101	25894557	A. Nomiya	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4404101	25894557	ES	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404101	25894557	ES	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404101	25894557	ES	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404101	25894557	ES	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404101	25894557	HF	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4404101	25894557	HK	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4404101	25894557	HN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404101	25894557	HN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404101	25894557	HN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404101	25894557	HN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404101	25894557	YH	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4404101	25894557	YS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4404101	25894557	YS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4743406	26855663	DG	PLoS5	Conceived and designed the experiments|Raising and collecting of the reagents and materials|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4743406	26855663	DG	PLoS5	Conceived and designed the experiments|Raising and collecting of the reagents and materials|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Raising and collecting of the reagents and materials	Performed the experiments	Investigation	YES
4743406	26855663	DG	PLoS5	Conceived and designed the experiments|Raising and collecting of the reagents and materials|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4743406	26855663	DG	PLoS5	Conceived and designed the experiments|Raising and collecting of the reagents and materials|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4743406	26855663	DG	PLoS5	Conceived and designed the experiments|Raising and collecting of the reagents and materials|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4743406	26855663	DG	PLoS5	Conceived and designed the experiments|Raising and collecting of the reagents and materials|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4743406	26855663	LW	PLoS5	Conceived and designed the experiments|Raising and collecting of the reagents and materials|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4743406	26855663	LW	PLoS5	Conceived and designed the experiments|Raising and collecting of the reagents and materials|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Raising and collecting of the reagents and materials	Performed the experiments	Investigation	YES
4743406	26855663	LW	PLoS5	Conceived and designed the experiments|Raising and collecting of the reagents and materials|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4743406	26855663	LW	PLoS5	Conceived and designed the experiments|Raising and collecting of the reagents and materials|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4743406	26855663	LW	PLoS5	Conceived and designed the experiments|Raising and collecting of the reagents and materials|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4743406	26855663	LW	PLoS5	Conceived and designed the experiments|Raising and collecting of the reagents and materials|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4743406	26855663	RB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4743406	26855663	RB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4743406	26855663	RB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4743406	26855663	TA	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4743406	26855663	TA	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4743406	26855663	TA	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4743406	26855663	TA	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5264435	27789275	F.G.H.	2	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5264435	27789275	H.J.L.	2	conceived and designed the study|took full responsibility for data collecting and accuracy|performed the meta-analysis and systematic review, and drafted the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5264435	27789275	H.J.L.	2	conceived and designed the study|took full responsibility for data collecting and accuracy|performed the meta-analysis and systematic review, and drafted the manuscript	took full responsibility for data collecting and accuracy	Performed the experiments	Investigation	YES
5264435	27789275	H.J.L.	2	conceived and designed the study|took full responsibility for data collecting and accuracy|performed the meta-analysis and systematic review, and drafted the manuscript	performed the meta-analysis and systematic review, and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5264435	27789275	J.L.R.	2	helped revise the manuscript	helped revise the manuscript	Wrote the paper	Writing - Review & Editing	YES
5264435	27789275	Q.L.	2	helped revise the manuscript	helped revise the manuscript	Wrote the paper	Writing - Review & Editing	YES
5264435	27789275	Q.S.	2	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5264435	27789275	S.Q.Z.	2	took full responsibility for data collecting and accuracy	took full responsibility for data collecting and accuracy	Performed the experiments	Investigation	YES
5264435	27789275	S.S.L.	2	took full responsibility for data collecting and accuracy	took full responsibility for data collecting and accuracy	Performed the experiments	Investigation	YES
5264435	27789275	W.B.W.	2	helped revise the manuscript	helped revise the manuscript	Wrote the paper	Writing - Review & Editing	YES
5264435	27789275	W.L.	2	took full responsibility for data collecting and accuracy|performed the meta-analysis and systematic review, and drafted the manuscript	took full responsibility for data collecting and accuracy	Performed the experiments	Investigation	YES
5264435	27789275	W.L.	2	took full responsibility for data collecting and accuracy|performed the meta-analysis and systematic review, and drafted the manuscript	performed the meta-analysis and systematic review, and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
4680631	26793311	Brian O. Kloster	7	Study design, data collection, data analysis, and writing. Jes S. lindholt: Study design, data analysis and writing	Study design, data collection, data analysis, and writing. Jes S. lindholt: Study design, data analysis and writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology	YES
4680631	26793311	Lars Lund	7	Study design, data collection and writing	Study design, data collection and writing	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology	YES
5507992	28751907	B. The	2	authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	Performed the experiments	Investigation	YES
4444752	26022654	AG	2	was responsible for the statistical analysis and writing of the manuscript|contributed to the plan of analysis and interpretation of the data	was responsible for the statistical analysis and writing of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4444752	26022654	AG	2	was responsible for the statistical analysis and writing of the manuscript|contributed to the plan of analysis and interpretation of the data	contributed to the plan of analysis and interpretation of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
4444752	26022654	All authors	2	commented on drafts of the manuscript and approved the final version	commented on drafts of the manuscript and approved the final version	Wrote the paper	Writing - Original Draft	YES
4444752	26022654	CK	2	contributed to the plan of analysis and interpretation of the data	contributed to the plan of analysis and interpretation of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
4444752	26022654	JS	2	contributed to the plan of analysis and interpretation of the data	contributed to the plan of analysis and interpretation of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
4444752	26022654	LGB	2	contributed to the plan of analysis and interpretation of the data	contributed to the plan of analysis and interpretation of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
4444752	26022654	LM	2	contributed to the plan of analysis and interpretation of the data	contributed to the plan of analysis and interpretation of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
4685201	26779339	All	2	listed as authors	listed as authors	-	-	NO
4745167	26858771	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5217662	28056772	BJ	2	in discussions and interpretation of results, and helped to draft the manuscript	in discussions and interpretation of results, and helped to draft the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5217662	28056772	BRJ	2	participated in the design of optimization algorithm and helped to draft the manuscript	participated in the design of optimization algorithm and helped to draft the manuscript	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Software|Writing - Original Draft	YES
5217662	28056772	HRA	2	participated in data curation, and helped to draft the manuscript	participated in data curation, and helped to draft the manuscript	Analyzed the data|Wrote the paper	Data curation|Writing - Original Draft	YES
5217662	28056772	IM	2	participated in the study design, in discussions and interpretation of results, and helped to draft the manuscript	participated in the study design, in discussions and interpretation of results, and helped to draft the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5217662	28056772	JACA	2	participated in discussions and interpretation of results, participated in the phylogenetic analysis, and helped to draft the manuscript	participated in discussions and interpretation of results, participated in the phylogenetic analysis, and helped to draft the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5217662	28056772	KM	2	participated in the phylogenetic analysis, in discussions and interpretation of results, and helped to draft the manuscript	participated in the phylogenetic analysis, in discussions and interpretation of results, and helped to draft the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5217662	28056772	ME	2	participated in conceiving the study, participated in its design and coordination, participated in data generation, in data curation, in the phylogenetic analysis, in discussions and interpretation of results, and helped to draft the manuscript	participated in conceiving the study, participated in its design and coordination, participated in data generation, in data curation, in the phylogenetic analysis, in discussions and interpretation of results, and helped to draft the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Data curation|Formal analysis|Investigation|Methodology|Project administration|Writing - Original Draft	YES
5217662	28056772	OM	2	participated in conceiving the study, carried out data generation and all computational analyses, participated in data analysis, in discussions and interpretation of results, and drafted the manuscript	participated in conceiving the study, carried out data generation and all computational analyses, participated in data analysis, in discussions and interpretation of results, and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
5217662	28056772	RH	2	in discussions and interpretation of results, and helped to draft the manuscript	in discussions and interpretation of results, and helped to draft the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5217662	28056772	STA	2	in discussions and interpretation of results, and helped to draft the manuscript	in discussions and interpretation of results, and helped to draft the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5217662	28056772	TGparticipated	2	in discussions and interpretation of results, and helped to draft the manuscript	in discussions and interpretation of results, and helped to draft the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5217662	28056772	VBB	2	participated in conceiving the study, participated in its design and coordination, in the optimization algorithm design, in data generation, in discussions and interpretation of results, and helped to draft the manuscript	participated in conceiving the study, participated in its design and coordination, in the optimization algorithm design, in data generation, in discussions and interpretation of results, and helped to draft the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Methodology|Project administration|Software|Writing - Original Draft	YES
5217662	28056772	XG	2	in discussions and interpretation of results, and helped to draft the manuscript	in discussions and interpretation of results, and helped to draft the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5217662	28056772	XL	2	participated in data curation, and helped to draft the manuscript	participated in data curation, and helped to draft the manuscript	Analyzed the data|Wrote the paper	Data curation|Writing - Original Draft	YES
4404103	25893406	ACS	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404103	25893406	ACS	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404103	25893406	AH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404103	25893406	AH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404103	25893406	AH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404103	25893406	AH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404103	25893406	AH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404103	25893406	CJL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404103	25893406	CJL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404103	25893406	CJL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404103	25893406	CJL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404103	25893406	CJL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404103	25893406	YIK	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404103	25893406	YIK	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404103	25893406	YIK	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404103	25893406	YIK	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404103	25893406	YX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404103	25893406	YX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4404103	25893406	YX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5508017	28751898	MN	PLoS52	performed research|analyzed data|wrote the paper|have contributed equally to this work	performed research	Performed the experiments	Investigation	YES
5508017	28751898	MN	PLoS52	performed research|analyzed data|wrote the paper|have contributed equally to this work	analyzed data	Analyzed the data	Formal analysis	YES
5508017	28751898	MN	PLoS52	performed research|analyzed data|wrote the paper|have contributed equally to this work	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5508017	28751898	MN	PLoS52	performed research|analyzed data|wrote the paper|have contributed equally to this work	have contributed equally to this work	-	-	NO
5508017	28751898	SM	PLoS52	designed research	designed research	Conceived and designed the experiments	Methodology	YES
5508017	28751898	SS	PLoS52	designed research|performed research|analyzed data|wrote the paper|have contributed equally to this work	designed research	Conceived and designed the experiments	Methodology	YES
5508017	28751898	SS	PLoS52	designed research|performed research|analyzed data|wrote the paper|have contributed equally to this work	performed research	Performed the experiments	Investigation	YES
5508017	28751898	SS	PLoS52	designed research|performed research|analyzed data|wrote the paper|have contributed equally to this work	analyzed data	Analyzed the data	Formal analysis	YES
5508017	28751898	SS	PLoS52	designed research|performed research|analyzed data|wrote the paper|have contributed equally to this work	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5508017	28751898	SS	PLoS52	designed research|performed research|analyzed data|wrote the paper|have contributed equally to this work	have contributed equally to this work	-	-	NO
5508017	28751898	SaK	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
5508017	28751898	ShK	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
5508017	28751898	TS	PLoS52	designed research|analyzed data|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
5508017	28751898	TS	PLoS52	designed research|analyzed data|wrote the paper	analyzed data	Analyzed the data	Formal analysis	YES
5508017	28751898	TS	PLoS52	designed research|analyzed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5508017	28751898	YI	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
5508017	28751898	YN	PLoS52	designed research	designed research	Conceived and designed the experiments	Methodology	YES
4748529	26865854	DX	1	Designed the study	Designed the study	Conceived and designed the experiments	Methodology	YES
4748529	26865854	HW	1	Designed the study	Designed the study	Conceived and designed the experiments	Methodology	YES
4685211	26779336	All authors	2	were involved with drafting and revising the manuscript	were involved with drafting and revising the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4685211	26779336	FS	2	were involved with the literature review and gathering and interpreting the patients clinical information	were involved with the literature review and gathering and interpreting the patients clinical information	Analyzed the data	Formal analysis	YES
4685211	26779336	KS	2	were involved with the literature review and gathering and interpreting the patients clinical information	were involved with the literature review and gathering and interpreting the patients clinical information	Analyzed the data	Formal analysis	YES
4685211	26779336	NB	2	were involved with the literature review and gathering and interpreting the patients clinical information|created the figures	were involved with the literature review and gathering and interpreting the patients clinical information	Analyzed the data	Formal analysis	YES
4685211	26779336	NB	2	were involved with the literature review and gathering and interpreting the patients clinical information|created the figures	created the figures	-	Visualization	YES
4685211	26779336	SA	2	were involved with the literature review and gathering and interpreting the patients clinical information	were involved with the literature review and gathering and interpreting the patients clinical information	Analyzed the data	Formal analysis	YES
4450240	26028156	AP	2	contributed to developing the concept, design and protocol for the study|contributed to data collection|reviewed the manuscript critically for intellectual content	contributed to developing the concept, design and protocol for the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4450240	26028156	AP	2	contributed to developing the concept, design and protocol for the study|contributed to data collection|reviewed the manuscript critically for intellectual content	contributed to data collection	Performed the experiments	Investigation	YES
4450240	26028156	AP	2	contributed to developing the concept, design and protocol for the study|contributed to data collection|reviewed the manuscript critically for intellectual content	reviewed the manuscript critically for intellectual content	Wrote the paper	Writing - Review & Editing	YES
4450240	26028156	All authors	2	read and approved the final draft of the submitted manuscript	read and approved the final draft of the submitted manuscript	Wrote the paper	Writing - Original Draft	YES
4450240	26028156	BM	2	contributed to developing the concept, design and protocol for the study|contributed to data collection|reviewed the manuscript critically for intellectual content	contributed to developing the concept, design and protocol for the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4450240	26028156	BM	2	contributed to developing the concept, design and protocol for the study|contributed to data collection|reviewed the manuscript critically for intellectual content	contributed to data collection	Performed the experiments	Investigation	YES
4450240	26028156	BM	2	contributed to developing the concept, design and protocol for the study|contributed to data collection|reviewed the manuscript critically for intellectual content	reviewed the manuscript critically for intellectual content	Wrote the paper	Writing - Review & Editing	YES
4450240	26028156	EBW	2	contributed to data collection|contributed to drafting the manuscript|reviewed the manuscript critically for intellectual content	contributed to data collection	Performed the experiments	Investigation	YES
4450240	26028156	EBW	2	contributed to data collection|contributed to drafting the manuscript|reviewed the manuscript critically for intellectual content	contributed to drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
4450240	26028156	EBW	2	contributed to data collection|contributed to drafting the manuscript|reviewed the manuscript critically for intellectual content	reviewed the manuscript critically for intellectual content	Wrote the paper	Writing - Review & Editing	YES
4450240	26028156	FC	2	contributed to developing the concept, design and protocol for the study|reviewed the manuscript critically for intellectual content	contributed to developing the concept, design and protocol for the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4450240	26028156	FC	2	contributed to developing the concept, design and protocol for the study|reviewed the manuscript critically for intellectual content	reviewed the manuscript critically for intellectual content	Wrote the paper	Writing - Review & Editing	YES
4450240	26028156	JAB	2	contributed to developing the concept, design and protocol for the study|contributed to data collection|contributed to drafting the manuscript|reviewed the manuscript critically for intellectual content	contributed to developing the concept, design and protocol for the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4450240	26028156	JAB	2	contributed to developing the concept, design and protocol for the study|contributed to data collection|contributed to drafting the manuscript|reviewed the manuscript critically for intellectual content	contributed to data collection	Performed the experiments	Investigation	YES
4450240	26028156	JAB	2	contributed to developing the concept, design and protocol for the study|contributed to data collection|contributed to drafting the manuscript|reviewed the manuscript critically for intellectual content	contributed to drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
4450240	26028156	JAB	2	contributed to developing the concept, design and protocol for the study|contributed to data collection|contributed to drafting the manuscript|reviewed the manuscript critically for intellectual content	reviewed the manuscript critically for intellectual content	Wrote the paper	Writing - Review & Editing	YES
4450240	26028156	JB	2	contributed to developing the concept, design and protocol for the study|contributed to data collection|assisted with data analysis and/or results interpretation|contributed to drafting the manuscript|reviewed the manuscript critically for intellectual content	contributed to developing the concept, design and protocol for the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4450240	26028156	JB	2	contributed to developing the concept, design and protocol for the study|contributed to data collection|assisted with data analysis and/or results interpretation|contributed to drafting the manuscript|reviewed the manuscript critically for intellectual content	contributed to data collection	Performed the experiments	Investigation	YES
4450240	26028156	JB	2	contributed to developing the concept, design and protocol for the study|contributed to data collection|assisted with data analysis and/or results interpretation|contributed to drafting the manuscript|reviewed the manuscript critically for intellectual content	assisted with data analysis and/or results interpretation	Analyzed the data	Formal analysis	YES
4450240	26028156	JB	2	contributed to developing the concept, design and protocol for the study|contributed to data collection|assisted with data analysis and/or results interpretation|contributed to drafting the manuscript|reviewed the manuscript critically for intellectual content	contributed to drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
4450240	26028156	JB	2	contributed to developing the concept, design and protocol for the study|contributed to data collection|assisted with data analysis and/or results interpretation|contributed to drafting the manuscript|reviewed the manuscript critically for intellectual content	reviewed the manuscript critically for intellectual content	Wrote the paper	Writing - Review & Editing	YES
4450240	26028156	JR	2	contributed to developing the concept, design and protocol for the study|contributed to data collection|reviewed the manuscript critically for intellectual content	contributed to developing the concept, design and protocol for the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4450240	26028156	JR	2	contributed to developing the concept, design and protocol for the study|contributed to data collection|reviewed the manuscript critically for intellectual content	contributed to data collection	Performed the experiments	Investigation	YES
4450240	26028156	JR	2	contributed to developing the concept, design and protocol for the study|contributed to data collection|reviewed the manuscript critically for intellectual content	reviewed the manuscript critically for intellectual content	Wrote the paper	Writing - Review & Editing	YES
4450240	26028156	JTC	2	contributed to developing the concept, design and protocol for the study|contributed to data collection|assisted with data analysis and/or results interpretation|contributed to drafting the manuscript|reviewed the manuscript critically for intellectual content	contributed to developing the concept, design and protocol for the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4450240	26028156	JTC	2	contributed to developing the concept, design and protocol for the study|contributed to data collection|assisted with data analysis and/or results interpretation|contributed to drafting the manuscript|reviewed the manuscript critically for intellectual content	contributed to data collection	Performed the experiments	Investigation	YES
4450240	26028156	JTC	2	contributed to developing the concept, design and protocol for the study|contributed to data collection|assisted with data analysis and/or results interpretation|contributed to drafting the manuscript|reviewed the manuscript critically for intellectual content	assisted with data analysis and/or results interpretation	Analyzed the data	Formal analysis	YES
4450240	26028156	JTC	2	contributed to developing the concept, design and protocol for the study|contributed to data collection|assisted with data analysis and/or results interpretation|contributed to drafting the manuscript|reviewed the manuscript critically for intellectual content	contributed to drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
4450240	26028156	JTC	2	contributed to developing the concept, design and protocol for the study|contributed to data collection|assisted with data analysis and/or results interpretation|contributed to drafting the manuscript|reviewed the manuscript critically for intellectual content	reviewed the manuscript critically for intellectual content	Wrote the paper	Writing - Review & Editing	YES
4450240	26028156	JWK	2	contributed to data collection|assisted with data analysis and/or results interpretation|contributed to drafting the manuscript|reviewed the manuscript critically for intellectual content	contributed to data collection	Performed the experiments	Investigation	YES
4450240	26028156	JWK	2	contributed to data collection|assisted with data analysis and/or results interpretation|contributed to drafting the manuscript|reviewed the manuscript critically for intellectual content	assisted with data analysis and/or results interpretation	Analyzed the data	Formal analysis	YES
4450240	26028156	JWK	2	contributed to data collection|assisted with data analysis and/or results interpretation|contributed to drafting the manuscript|reviewed the manuscript critically for intellectual content	contributed to drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
4450240	26028156	JWK	2	contributed to data collection|assisted with data analysis and/or results interpretation|contributed to drafting the manuscript|reviewed the manuscript critically for intellectual content	reviewed the manuscript critically for intellectual content	Wrote the paper	Writing - Review & Editing	YES
4450240	26028156	MEH	2	had overall responsibility for implementing the study, and conceived and designed the study, developed the study protocol, collected and analysed the data, and wrote the manuscript	had overall responsibility for implementing the study, and conceived and designed the study, developed the study protocol, collected and analysed the data, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4450240	26028156	NK	2	contributed to developing the concept, design and protocol for the study|contributed to data collection|reviewed the manuscript critically for intellectual content	contributed to developing the concept, design and protocol for the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4450240	26028156	NK	2	contributed to developing the concept, design and protocol for the study|contributed to data collection|reviewed the manuscript critically for intellectual content	contributed to data collection	Performed the experiments	Investigation	YES
4450240	26028156	NK	2	contributed to developing the concept, design and protocol for the study|contributed to data collection|reviewed the manuscript critically for intellectual content	reviewed the manuscript critically for intellectual content	Wrote the paper	Writing - Review & Editing	YES
4450240	26028156	SG	2	contributed to developing the concept, design and protocol for the study|assisted with data analysis and/or results interpretation|contributed to drafting the manuscript|reviewed the manuscript critically for intellectual content	contributed to developing the concept, design and protocol for the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4450240	26028156	SG	2	contributed to developing the concept, design and protocol for the study|assisted with data analysis and/or results interpretation|contributed to drafting the manuscript|reviewed the manuscript critically for intellectual content	assisted with data analysis and/or results interpretation	Analyzed the data	Formal analysis	YES
4450240	26028156	SG	2	contributed to developing the concept, design and protocol for the study|assisted with data analysis and/or results interpretation|contributed to drafting the manuscript|reviewed the manuscript critically for intellectual content	contributed to drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
4450240	26028156	SG	2	contributed to developing the concept, design and protocol for the study|assisted with data analysis and/or results interpretation|contributed to drafting the manuscript|reviewed the manuscript critically for intellectual content	reviewed the manuscript critically for intellectual content	Wrote the paper	Writing - Review & Editing	YES
4450240	26028156	SNE	2	contributed to data collection|reviewed the manuscript critically for intellectual content	contributed to data collection	Performed the experiments	Investigation	YES
4450240	26028156	SNE	2	contributed to data collection|reviewed the manuscript critically for intellectual content	reviewed the manuscript critically for intellectual content	Wrote the paper	Writing - Review & Editing	YES
4404104	25893856	ABS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404104	25893856	ABS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404104	25893856	ADO	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404104	25893856	ADO	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4404104	25893856	AMB	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404104	25893856	FSMC	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404104	25893856	FSMC	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4404104	25893856	MM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4404104	25893856	MM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404104	25893856	RC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404104	25893856	RC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404104	25893856	RC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404104	25893856	RGM	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404104	25893856	RT	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404104	25893856	RT	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4980116	27525221	All authors	2	have reviewed the paper and agree to its publication	have reviewed the paper and agree to its publication	Wrote the paper	Writing - Review & Editing	YES
4980116	27525221	Loren J. Schleiden	2	contributed to preparing this manuscript for publication, data analysis, and interpretation of results	contributed to preparing this manuscript for publication, data analysis, and interpretation of results	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
4980116	27525221	Michelle A. Chui	2	was involved in study design, data interpretation, and drafting the final manuscript	was involved in study design, data interpretation, and drafting the final manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
4980116	27525221	Olufunmilola K. Odukoya	2	was responsible for study conceptualization, data collection, analysis, and writing this final report	was responsible for study conceptualization, data collection, analysis, and writing this final report	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation	YES
5217664	28056774	Both authors	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5217664	28056774	SJF	2	conceived and supervised the study	conceived and supervised the study	Conceived and designed the experiments	Conceptualization|Supervision	YES
5217664	28056774	SWP	2	conducted all bioinformatic and statistical analysis	conducted all bioinformatic and statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5264483	27810310	A.R.	CRediT	Methodology|Supervision	Methodology	Performed the experiments	Methodology	YES
5264483	27810310	A.R.	CRediT	Methodology|Supervision	Supervision	-	Supervision	YES
5264483	27810310	D.A.	CRediT	Investigation|Resources	Investigation	Performed the experiments	Investigation	YES
5264483	27810310	D.A.	CRediT	Investigation|Resources	Resources	Contributed reagents/materials/analysis tools	Resources	YES
5264483	27810310	H.K.S.	CRediT	Methodology|Writing--review & editing|Supervision	Methodology	Performed the experiments	Methodology	YES
5264483	27810310	H.K.S.	CRediT	Methodology|Writing--review & editing|Supervision	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
5264483	27810310	H.K.S.	CRediT	Methodology|Writing--review & editing|Supervision	Supervision	-	Supervision	YES
5264483	27810310	J.E.C.	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
5264483	27810310	J.L.	CRediT	Investigation|Resources	Investigation	Performed the experiments	Investigation	YES
5264483	27810310	J.L.	CRediT	Investigation|Resources	Resources	Contributed reagents/materials/analysis tools	Resources	YES
5264483	27810310	L.K.S.	CRediT	Methodology|Investigation|Writing--original draft|Visualization|Project administration	Methodology	Performed the experiments	Methodology	YES
5264483	27810310	L.K.S.	CRediT	Methodology|Investigation|Writing--original draft|Visualization|Project administration	Investigation	Performed the experiments	Investigation	YES
5264483	27810310	L.K.S.	CRediT	Methodology|Investigation|Writing--original draft|Visualization|Project administration	Writing--original draft	Wrote the paper	Writing - Original Draft	YES
5264483	27810310	L.K.S.	CRediT	Methodology|Investigation|Writing--original draft|Visualization|Project administration	Visualization	Analyzed the data	Visualization	YES
5264483	27810310	L.K.S.	CRediT	Methodology|Investigation|Writing--original draft|Visualization|Project administration	Project administration	-	Project administration	YES
5264483	27810310	M-L.L.	CRediT	Investigation|Resources	Investigation	Performed the experiments	Investigation	YES
5264483	27810310	M-L.L.	CRediT	Investigation|Resources	Resources	Contributed reagents/materials/analysis tools	Resources	YES
5264483	27810310	M.C.	CRediT	Resources	Resources	Contributed reagents/materials/analysis tools	Resources	YES
5264483	27810310	M.J.L.	CRediT	Methodology|Investigation|Writing--review & editing	Methodology	Performed the experiments	Methodology	YES
5264483	27810310	M.J.L.	CRediT	Methodology|Investigation|Writing--review & editing	Investigation	Performed the experiments	Investigation	YES
5264483	27810310	M.J.L.	CRediT	Methodology|Investigation|Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
5264483	27810310	M.S.	CRediT	Investigation|Resources|Writing--review & editing	Investigation	Performed the experiments	Investigation	YES
5264483	27810310	M.S.	CRediT	Investigation|Resources|Writing--review & editing	Resources	Contributed reagents/materials/analysis tools	Resources	YES
5264483	27810310	M.S.	CRediT	Investigation|Resources|Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
5264483	27810310	M.T.S.	CRediT	Investigation|Writing--review & editing	Investigation	Performed the experiments	Investigation	YES
5264483	27810310	M.T.S.	CRediT	Investigation|Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
5264483	27810310	N.M.	CRediT	Methodology|Formal analysis|Investigation|Writing--review & editing|Visualization	Methodology	Performed the experiments	Methodology	YES
5264483	27810310	N.M.	CRediT	Methodology|Formal analysis|Investigation|Writing--review & editing|Visualization	Formal analysis	Analyzed the data	Formal analysis	YES
5264483	27810310	N.M.	CRediT	Methodology|Formal analysis|Investigation|Writing--review & editing|Visualization	Investigation	Performed the experiments	Investigation	YES
5264483	27810310	N.M.	CRediT	Methodology|Formal analysis|Investigation|Writing--review & editing|Visualization	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
5264483	27810310	N.M.	CRediT	Methodology|Formal analysis|Investigation|Writing--review & editing|Visualization	Visualization	Analyzed the data	Visualization	YES
5264483	27810310	N.Y.	CRediT	Investigation|Writing--review & editing	Investigation	Performed the experiments	Investigation	YES
5264483	27810310	N.Y.	CRediT	Investigation|Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
5264483	27810310	R.B.	CRediT	Conceptualization|Writing--review & editing|Supervision	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
5264483	27810310	R.B.	CRediT	Conceptualization|Writing--review & editing|Supervision	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
5264483	27810310	R.B.	CRediT	Conceptualization|Writing--review & editing|Supervision	Supervision	-	Supervision	YES
5264483	27810310	S.L.	CRediT	Conceptualization|Methodology|Resources|Writing--review & editing|Supervision	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
5264483	27810310	S.L.	CRediT	Conceptualization|Methodology|Resources|Writing--review & editing|Supervision	Methodology	Performed the experiments	Methodology	YES
5264483	27810310	S.L.	CRediT	Conceptualization|Methodology|Resources|Writing--review & editing|Supervision	Resources	Contributed reagents/materials/analysis tools	Resources	YES
5264483	27810310	S.L.	CRediT	Conceptualization|Methodology|Resources|Writing--review & editing|Supervision	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
5264483	27810310	S.L.	CRediT	Conceptualization|Methodology|Resources|Writing--review & editing|Supervision	Supervision	-	Supervision	YES
5508019	28751905	All authors	2	contributed to discussion of the results and approved the final manuscript	contributed to discussion of the results and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5508019	28751905	QHP	2	designed the experiments on vineyard samples|provided suggestions on statistical analysis and visualization of results, and revised the manuscript	designed the experiments on vineyard samples	Conceived and designed the experiments	Methodology	YES
5508019	28751905	QHP	2	designed the experiments on vineyard samples|provided suggestions on statistical analysis and visualization of results, and revised the manuscript	provided suggestions on statistical analysis and visualization of results, and revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Visualization|Writing - Review & Editing	YES
5508019	28751905	The authors	2	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	Performed the experiments	Investigation	YES
5508019	28751905	XYL	2	provided statistical analysis and drafted the initial manuscript	provided statistical analysis and drafted the initial manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5508019	28751905	YW	2	provided statistical analysis and drafted the initial manuscript	provided statistical analysis and drafted the initial manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4756418	26889204	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4756418	26889204	BA	2	approved the proposal with some revisions, participated in data analysis and reviewed the manuscript	approved the proposal with some revisions, participated in data analysis and reviewed the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4756418	26889204	DZ	2	conceived the idea and wrote the proposal, participated in data collection process, analyze date and draft the paper	conceived the idea and wrote the proposal, participated in data collection process, analyze date and draft the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Data curation|Formal analysis|Investigation|Writing - Original Draft	YES
4756418	26889204	ZA	2	approved the proposal with some revisions, participated in data analysis and reviewed the manuscript	approved the proposal with some revisions, participated in data analysis and reviewed the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4404134	25894547	AC	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4404134	25894547	AC	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4404134	25894547	EBK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404134	25894547	EBK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404134	25894547	EBK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404134	25894547	EBK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404134	25894547	EBK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404134	25894547	ER	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404134	25894547	ER	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404134	25894547	ER	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404134	25894547	MGP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404134	25894547	MGP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404134	25894547	MGP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404134	25894547	MGP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404134	25894547	MGP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404134	25894547	VPE	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404134	25894547	VPE	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404134	25894547	VPE	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404134	25894547	VPE	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4450241	26028155	AL	2	implemented the study and collected specimens and data	implemented the study and collected specimens and data	Performed the experiments	Investigation	YES
4450241	26028155	EW	2	implemented the study and collected specimens and data|designed and implemented electronic data collection and storage	implemented the study and collected specimens and data	Performed the experiments	Investigation	YES
4450241	26028155	EW	2	implemented the study and collected specimens and data|designed and implemented electronic data collection and storage	designed and implemented electronic data collection and storage	Conceived and designed the experiments|Performed the experiments	Investigation	YES
4450241	26028155	HB	2	conceived and designed the study and participated in its implementation|implemented the study and collected specimens and data|wrote the manuscript	conceived and designed the study and participated in its implementation	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
4450241	26028155	HB	2	conceived and designed the study and participated in its implementation|implemented the study and collected specimens and data|wrote the manuscript	implemented the study and collected specimens and data	Performed the experiments	Investigation	YES
4450241	26028155	HB	2	conceived and designed the study and participated in its implementation|implemented the study and collected specimens and data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4450241	26028155	JM	2	conceived and designed the study and participated in its implementation|implemented the study and collected specimens and data	conceived and designed the study and participated in its implementation	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
4450241	26028155	JM	2	conceived and designed the study and participated in its implementation|implemented the study and collected specimens and data	implemented the study and collected specimens and data	Performed the experiments	Investigation	YES
4450241	26028155	LO	2	implemented the study and collected specimens and data	implemented the study and collected specimens and data	Performed the experiments	Investigation	YES
4450241	26028155	ME	2	conceived and designed the study and participated in its implementation|wrote the manuscript	conceived and designed the study and participated in its implementation	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
4450241	26028155	ME	2	conceived and designed the study and participated in its implementation|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4450241	26028155	MM	2	implemented the study and collected specimens and data	implemented the study and collected specimens and data	Performed the experiments	Investigation	YES
4450241	26028155	MPH	2	coordinated the implementation of the study and data collection	coordinated the implementation of the study and data collection	Performed the experiments	Investigation|Project administration	YES
4450241	26028155	QL	2	prepared data for analysis|performed the statistical analysis	prepared data for analysis	Analyzed the data	Formal analysis	YES
4450241	26028155	QL	2	prepared data for analysis|performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
4450241	26028155	SL	2	conceived and designed the study and participated in its implementation|wrote the manuscript	conceived and designed the study and participated in its implementation	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
4450241	26028155	SL	2	conceived and designed the study and participated in its implementation|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4450241	26028155	SM	2	implemented the study and collected specimens and data|performed laboratory tests	implemented the study and collected specimens and data	Performed the experiments	Investigation	YES
4450241	26028155	SM	2	implemented the study and collected specimens and data|performed laboratory tests	performed laboratory tests	Performed the experiments	Investigation	YES
4450241	26028155	VD	2	conceived and designed the study and participated in its implementation|performed the statistical analysis|wrote the manuscript	conceived and designed the study and participated in its implementation	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
4450241	26028155	VD	2	conceived and designed the study and participated in its implementation|performed the statistical analysis|wrote the manuscript	performed the statistical analysis	Analyzed the data	Formal analysis	YES
4450241	26028155	VD	2	conceived and designed the study and participated in its implementation|performed the statistical analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4450241	26028155	VN	2	conceived and designed the study and participated in its implementation|performed the statistical analysis|wrote the manuscript	conceived and designed the study and participated in its implementation	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
4450241	26028155	VN	2	conceived and designed the study and participated in its implementation|performed the statistical analysis|wrote the manuscript	performed the statistical analysis	Analyzed the data	Formal analysis	YES
4450241	26028155	VN	2	conceived and designed the study and participated in its implementation|performed the statistical analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4685239	26779334	Betina Norman Jepsen	1	Study design|Data collection|Data analysis and interpretation|Drafting of manuscript|Critical revision of manuscript	Study design	Conceived and designed the experiments	Methodology	YES
4685239	26779334	Betina Norman Jepsen	1	Study design|Data collection|Data analysis and interpretation|Drafting of manuscript|Critical revision of manuscript	Data collection	Performed the experiments	Investigation	YES
4685239	26779334	Betina Norman Jepsen	1	Study design|Data collection|Data analysis and interpretation|Drafting of manuscript|Critical revision of manuscript	Data analysis and interpretation	Analyzed the data	Formal analysis	YES
4685239	26779334	Betina Norman Jepsen	1	Study design|Data collection|Data analysis and interpretation|Drafting of manuscript|Critical revision of manuscript	Drafting of manuscript	Wrote the paper	Writing - Original Draft	YES
4685239	26779334	Betina Norman Jepsen	1	Study design|Data collection|Data analysis and interpretation|Drafting of manuscript|Critical revision of manuscript	Critical revision of manuscript	Wrote the paper	Writing - Review & Editing	YES
4685239	26779334	Frank Viborg Mortensen	1	Study design|Data analysis and interpretation|Drafting of manuscript|Critical revision of manuscript	Study design	Conceived and designed the experiments	Methodology	YES
4685239	26779334	Frank Viborg Mortensen	1	Study design|Data analysis and interpretation|Drafting of manuscript|Critical revision of manuscript	Data analysis and interpretation	Analyzed the data	Formal analysis	YES
4685239	26779334	Frank Viborg Mortensen	1	Study design|Data analysis and interpretation|Drafting of manuscript|Critical revision of manuscript	Drafting of manuscript	Wrote the paper	Writing - Original Draft	YES
4685239	26779334	Frank Viborg Mortensen	1	Study design|Data analysis and interpretation|Drafting of manuscript|Critical revision of manuscript	Critical revision of manuscript	Wrote the paper	Writing - Review & Editing	YES
4685239	26779334	Holger Jon Moller	1	Critical revision of manuscript	Critical revision of manuscript	Wrote the paper	Writing - Review & Editing	YES
4685239	26779334	Jens Randel Nyengaard	1	Critical revision of manuscript	Critical revision of manuscript	Wrote the paper	Writing - Review & Editing	YES
4685239	26779334	Jonas Heilskov Graversen	1	Study design|Critical revision of manuscript	Study design	Conceived and designed the experiments	Methodology	YES
4685239	26779334	Jonas Heilskov Graversen	1	Study design|Critical revision of manuscript	Critical revision of manuscript	Wrote the paper	Writing - Review & Editing	YES
4685239	26779334	Kasper Jarlhelt Andersen	1	Study design|Data analysis and interpretation|Drafting of manuscript|Critical revision of manuscript	Study design	Conceived and designed the experiments	Methodology	YES
4685239	26779334	Kasper Jarlhelt Andersen	1	Study design|Data analysis and interpretation|Drafting of manuscript|Critical revision of manuscript	Data analysis and interpretation	Analyzed the data	Formal analysis	YES
4685239	26779334	Kasper Jarlhelt Andersen	1	Study design|Data analysis and interpretation|Drafting of manuscript|Critical revision of manuscript	Drafting of manuscript	Wrote the paper	Writing - Original Draft	YES
4685239	26779334	Kasper Jarlhelt Andersen	1	Study design|Data analysis and interpretation|Drafting of manuscript|Critical revision of manuscript	Critical revision of manuscript	Wrote the paper	Writing - Review & Editing	YES
4685239	26779334	Pia Svendsen	1	Critical revision of manuscript	Critical revision of manuscript	Wrote the paper	Writing - Review & Editing	YES
4685239	26779334	Riegels Knudsen	1	Study design|Data analysis and interpretation|Drafting of manuscript|Critical revision of manuscript	Study design	Conceived and designed the experiments	Methodology	YES
4685239	26779334	Riegels Knudsen	1	Study design|Data analysis and interpretation|Drafting of manuscript|Critical revision of manuscript	Data analysis and interpretation	Analyzed the data	Formal analysis	YES
4685239	26779334	Riegels Knudsen	1	Study design|Data analysis and interpretation|Drafting of manuscript|Critical revision of manuscript	Drafting of manuscript	Wrote the paper	Writing - Original Draft	YES
4685239	26779334	Riegels Knudsen	1	Study design|Data analysis and interpretation|Drafting of manuscript|Critical revision of manuscript	Critical revision of manuscript	Wrote the paper	Writing - Review & Editing	YES
4685239	26779334	Soren Kragh Moestrup	1	Critical revision of manuscript	Critical revision of manuscript	Wrote the paper	Writing - Review & Editing	YES
4685239	26779334	Stephen Hamilton-Dutoit	1	Critical revision of manuscript	Critical revision of manuscript	Wrote the paper	Writing - Review & Editing	YES
5219650	28061744	CF	2	designed the study|contributed to the writing of the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5219650	28061744	CF	2	designed the study|contributed to the writing of the manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5219650	28061744	KV	2	contributed to the writing of the manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5219650	28061744	PZ	2	conducted data analysis	conducted data analysis	Analyzed the data	Formal analysis	YES
5219650	28061744	QS	2	conducted data analysis	conducted data analysis	Analyzed the data	Formal analysis	YES
5219650	28061744	SZ	2	conducted data analysis	conducted data analysis	Analyzed the data	Formal analysis	YES
5219650	28061744	WZ	2	contributed to the writing of the manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5219650	28061744	YG	2	designed the study|contributed to the writing of the manuscript|conducted data analysis	designed the study	Conceived and designed the experiments	Methodology	YES
5219650	28061744	YG	2	designed the study|contributed to the writing of the manuscript|conducted data analysis	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5219650	28061744	YG	2	designed the study|contributed to the writing of the manuscript|conducted data analysis	conducted data analysis	Analyzed the data	Formal analysis	YES
5219650	28061744	YX	2	prepared the sample and extracted rna	prepared the sample and extracted rna	Performed the experiments	Investigation	YES
5360572	28233730	CG	2	supervised design, data analysis and interpretation|wrote the manuscript	supervised design, data analysis and interpretation	Conceived and designed the experiments|Analyzed the data	Formal analysis|Supervision	YES
5360572	28233730	CG	2	supervised design, data analysis and interpretation|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5360572	28233730	ELM	2	designed and performed the in vitro experiments, analyzed the data and interpreted the results|wrote the manuscript	designed and performed the in vitro experiments, analyzed the data and interpreted the results	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5360572	28233730	ELM	2	designed and performed the in vitro experiments, analyzed the data and interpreted the results|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5360572	28233730	EP	2	helped with the protein refolding and purification	helped with the protein refolding and purification	Performed the experiments	Investigation	YES
5360572	28233730	ES	2	contributed to the in vitro proliferation studies	contributed to the in vitro proliferation studies	Performed the experiments	Investigation	YES
5360572	28233730	IB	2	performed the in vivo tumor experiments and interpreted the results	performed the in vivo tumor experiments and interpreted the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5360572	28233730	LS	2	performed the in vivo tumor experiments and interpreted the results|wrote the manuscript	performed the in vivo tumor experiments and interpreted the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5360572	28233730	LS	2	performed the in vivo tumor experiments and interpreted the results|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5360572	28233730	SCA	2	supervised design, data analysis and interpretation|wrote the manuscript	supervised design, data analysis and interpretation	Conceived and designed the experiments|Analyzed the data	Formal analysis|Supervision	YES
5360572	28233730	SCA	2	supervised design, data analysis and interpretation|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5360572	28233730	SGN	2	supervised design, data analysis and interpretation	supervised design, data analysis and interpretation	Conceived and designed the experiments|Analyzed the data	Formal analysis|Supervision	YES
5360572	28233730	TQ	2	performed the in vivo tumor experiments and interpreted the results|wrote the manuscript	performed the in vivo tumor experiments and interpreted the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5360572	28233730	TQ	2	performed the in vivo tumor experiments and interpreted the results|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5360572	28233730	UAR	2	acquired the crystallography data and provided valuable help with the analysis	acquired the crystallography data and provided valuable help with the analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5508022	28751899	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5508022	28751899	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
5508022	28751899	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5508022	28751899	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5508022	28751899	LG	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5508022	28751899	MQ	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5508022	28751899	WZ	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5508022	28751899	YL	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
5508022	28751899	YL	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5508022	28751899	YT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5508022	28751899	YT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5508022	28751899	YT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404135	25894615	CP	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404135	25894615	GJ	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404135	25894615	JE	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4404135	25894615	LZ	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404135	25894615	LZ	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404135	25894615	LZ	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404135	25894615	MXW	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404135	25894615	QC	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404135	25894615	QC	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404135	25894615	QC	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404135	25894615	QC	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404135	25894615	YR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404135	25894615	YR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404135	25894615	YR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404135	25894615	YR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404135	25894615	YR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4452736	26037151	All of the authors	2	contributed to the conception of the study and collection of data, as well as to analyses and interpretation of data	contributed to the conception of the study and collection of data, as well as to analyses and interpretation of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
4452736	26037151	MW	2	was critically reviewed and subsequently approved by all authors	was critically reviewed and subsequently approved by all authors	-	-	NO
4452736	26037151	NW	2	was critically reviewed and subsequently approved by all authors	was critically reviewed and subsequently approved by all authors	-	-	NO
4452736	26037151	TK	2	was critically reviewed and subsequently approved by all authors	was critically reviewed and subsequently approved by all authors	-	-	NO
4687461	26793312	AS	2	have made substantial contribution to its design|helped in the coordination of this work|has been involved in drafting the manuscript and in its sequences alignment, too	have made substantial contribution to its design	Conceived and designed the experiments	-	YES
4687461	26793312	AS	2	have made substantial contribution to its design|helped in the coordination of this work|has been involved in drafting the manuscript and in its sequences alignment, too	helped in the coordination of this work	-	Project administration	YES
4687461	26793312	AS	2	have made substantial contribution to its design|helped in the coordination of this work|has been involved in drafting the manuscript and in its sequences alignment, too	has been involved in drafting the manuscript and in its sequences alignment, too	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4687461	26793312	GP	2	have made substantial contribution to its design	have made substantial contribution to its design	Conceived and designed the experiments	-	YES
4687461	26793312	LB	2	have participated in the acquisition, analysis and clinic-pathological correlations of data	have participated in the acquisition, analysis and clinic-pathological correlations of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4687461	26793312	LLM	2	have participated in the acquisition, analysis and clinic-pathological correlations of data	have participated in the acquisition, analysis and clinic-pathological correlations of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4687461	26793312	LR	2	has revised it critically for important intellectual content, giving final approval of the version to be published	has revised it critically for important intellectual content, giving final approval of the version to be published	Wrote the paper	Writing - Review & Editing	YES
4687461	26793312	PB	2	has revised it critically for important intellectual content, giving final approval of the version to be published	has revised it critically for important intellectual content, giving final approval of the version to be published	Wrote the paper	Writing - Review & Editing	YES
4687461	26793312	RS	2	conceived of the study	conceived of the study	Conceived and designed the experiments	Conceptualization	YES
5419341	28970393	Antoine Bruneau-Bouchard	2	was responsible for the study implementation, results interpretations, and manuscript editing	was responsible for the study implementation, results interpretations, and manuscript editing	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
5419341	28970393	Kerry Mansell	2	was responsible for the study conception and implementation, results interpretations, and manuscript preparation	was responsible for the study conception and implementation, results interpretations, and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
5419341	28970393	Vincent Bruni-Bossio	2	was responsible for the study implementation, and manuscript editing	was responsible for the study implementation, and manuscript editing	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5219651	28061751	NZ	2	participated in rna extraction	participated in rna extraction	Performed the experiments	Investigation	YES
5219651	28061751	PW	2	participated in rna extraction	participated in rna extraction	Performed the experiments	Investigation	YES
5219651	28061751	SW	2	participated in rna extraction	participated in rna extraction	Performed the experiments	Investigation	YES
4756447	26889203	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4756447	26889203	BS	2	designed the study|drafted and revised the manuscript critically for important intellectual content and gave final approval	designed the study	Conceived and designed the experiments	Methodology	YES
4756447	26889203	BS	2	designed the study|drafted and revised the manuscript critically for important intellectual content and gave final approval	drafted and revised the manuscript critically for important intellectual content and gave final approval	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4756447	26889203	GD	2	drafted and revised the manuscript critically for important intellectual content and gave final approval	drafted and revised the manuscript critically for important intellectual content and gave final approval	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4756447	26889203	PA	2	drafted and revised the manuscript critically for important intellectual content and gave final approval	drafted and revised the manuscript critically for important intellectual content and gave final approval	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4756447	26889203	PN	2	drafted and revised the manuscript critically for important intellectual content and gave final approval	drafted and revised the manuscript critically for important intellectual content and gave final approval	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4756447	26889203	RAB	2	conceived the research idea|designed the study|drafted and revised the manuscript critically for important intellectual content and gave final approval	conceived the research idea	Conceived and designed the experiments	Conceptualization	YES
4756447	26889203	RAB	2	conceived the research idea|designed the study|drafted and revised the manuscript critically for important intellectual content and gave final approval	designed the study	Conceived and designed the experiments	Methodology	YES
4756447	26889203	RAB	2	conceived the research idea|designed the study|drafted and revised the manuscript critically for important intellectual content and gave final approval	drafted and revised the manuscript critically for important intellectual content and gave final approval	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4700193	26835008	ALW	2	authors undertook the literature review, contributed to data collection, checking and analysis, drafting and revising the article|was the principal author and final approver	authors undertook the literature review, contributed to data collection, checking and analysis, drafting and revising the article	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
4700193	26835008	ALW	2	authors undertook the literature review, contributed to data collection, checking and analysis, drafting and revising the article|was the principal author and final approver	was the principal author and final approver	Wrote the paper	Writing - Original Draft	YES
4700193	26835008	All	2	authors undertook the literature review, contributed to data collection, checking and analysis, drafting and revising the article	authors undertook the literature review, contributed to data collection, checking and analysis, drafting and revising the article	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5360581	28258922	AV	2	were involved in data collection	were involved in data collection	Performed the experiments	Investigation	YES
5360581	28258922	CCH	2	were involved in data collection	were involved in data collection	Performed the experiments	Investigation	YES
5360581	28258922	IMG	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5360581	28258922	JG	2	were involved in data collection	were involved in data collection	Performed the experiments	Investigation	YES
5360581	28258922	JS	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5360581	28258922	POW	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5360581	28258922	RJH	2	were involved in data collection	were involved in data collection	Performed the experiments	Investigation	YES
5360581	28258922	RT	2	conducted the analyses	conducted the analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5360581	28258922	SC	2	conducted the literature search and designed all figures|conducted the analyses	conducted the literature search and designed all figures	Conceived and designed the experiments|Performed the experiments	Formal analysis|Investigation|Visualization	YES
5360581	28258922	SC	2	conducted the literature search and designed all figures|conducted the analyses	conducted the analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5360581	28258922	TS	2	conducted the analyses	conducted the analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5219666	28061813	GJ	2	designed the project and wrote the manuscript	designed the project and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5219666	28061813	GL	2	designed the project and wrote the manuscript	designed the project and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5219666	28061813	PL	2	carried out the dna extraction and the laboratory work	carried out the dna extraction and the laboratory work	Performed the experiments	Investigation	YES
5219666	28061813	QZ	2	collected the plant materials and carried out the experiment	collected the plant materials and carried out the experiment	Performed the experiments	Investigation	YES
5219666	28061813	RH	2	collected the plant materials and carried out the experiment	collected the plant materials and carried out the experiment	Performed the experiments	Investigation	YES
5219666	28061813	SF	2	performed the high-throughput sequencing and data analysis	performed the high-throughput sequencing and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5219666	28061813	SH	2	assisted with the high-throughput sequencing	assisted with the high-throughput sequencing	Performed the experiments	Investigation	YES
5219666	28061813	SL	2	assisted with the high-throughput sequencing	assisted with the high-throughput sequencing	Performed the experiments	Investigation	YES
5219666	28061813	XM	2	carried out the dna extraction and the laboratory work	carried out the dna extraction and the laboratory work	Performed the experiments	Investigation	YES
5219666	28061813	YH	2	carried out the dna extraction and the laboratory work	carried out the dna extraction and the laboratory work	Performed the experiments	Investigation	YES
4404136	25894208	AB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4404136	25894208	AEM	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404136	25894208	AFM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404136	25894208	AMM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4404136	25894208	DH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404136	25894208	DH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404136	25894208	DH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404136	25894208	FE	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4404136	25894208	FE	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404136	25894208	GF	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404136	25894208	HFL	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404136	25894208	HFL	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404136	25894208	HK	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404136	25894208	KK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4404136	25894208	KK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404136	25894208	MC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404136	25894208	MG	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404136	25894208	MM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404136	25894208	OB	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404136	25894208	PS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404136	25894208	PS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404136	25894208	PS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404136	25894208	RK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4404136	25894208	RK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404136	25894208	SU-S	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4404136	25894208	TS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4404136	25894208	ZK	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
3506896	23213300	All other authors	2	contributed to the methodology, analysis and commented on drafts of the paper	contributed to the methodology, analysis and commented on drafts of the paper	Performed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3506896	23213300	M. Lambri	2	wrote the proposal, sought ethical approval, collected and analysed the data, and authored and edited the paper	wrote the proposal, sought ethical approval, collected and analysed the data, and authored and edited the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5508023	28751906	BD	PLoS52	carried out experiments and analysis	carried out experiments and analysis	Performed the experiments	Investigation	YES
5508023	28751906	IC	PLoS52	designed the study|carried out experiments and analysis|wrote the paper	designed the study	Conceived and designed the experiments	Methodology	YES
5508023	28751906	IC	PLoS52	designed the study|carried out experiments and analysis|wrote the paper	carried out experiments and analysis	Performed the experiments	Investigation	YES
5508023	28751906	IC	PLoS52	designed the study|carried out experiments and analysis|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5508023	28751906	LR	PLoS52	designed the study|wrote the paper	designed the study	Conceived and designed the experiments	Methodology	YES
5508023	28751906	LR	PLoS52	designed the study|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5508023	28751906	MA	PLoS52	carried out experiments and analysis	carried out experiments and analysis	Performed the experiments	Investigation	YES
5508023	28751906	PS	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5508023	28751906	RW	PLoS52	designed the study|wrote the paper	designed the study	Conceived and designed the experiments	Methodology	YES
5508023	28751906	RW	PLoS52	designed the study|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5508023	28751906	SM	PLoS52	carried out experiments and analysis	carried out experiments and analysis	Performed the experiments	Investigation	YES
4757996	26893605	AGB	2	conceived the study, designed the protocol, contributed to analysis and interpretation of data, and drafted the first version of the manuscript	conceived the study, designed the protocol, contributed to analysis and interpretation of data, and drafted the first version of the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Methodology|Resources|Writing - Original Draft	YES
4757996	26893605	All authors	2	contributed to manuscript revisions and approved the final version for publication|read and approved the final manuscript	contributed to manuscript revisions and approved the final version for publication	Wrote the paper	Writing - Review & Editing	YES
4757996	26893605	All authors	2	contributed to manuscript revisions and approved the final version for publication|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4757996	26893605	DH	2	contributed to study design and interpretation of data	contributed to study design and interpretation of data	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Methodology|Resources	YES
4757996	26893605	JET	2	contributed to study design and interpretation of data	contributed to study design and interpretation of data	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Methodology|Resources	YES
4757996	26893605	JGJ	2	contributed to study design and interpretation of data	contributed to study design and interpretation of data	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Methodology|Resources	YES
4757996	26893605	LCI	2	conceived the study, designed the protocol, contributed to analysis and interpretation of data, and drafted the first version of the manuscript	conceived the study, designed the protocol, contributed to analysis and interpretation of data, and drafted the first version of the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Methodology|Resources|Writing - Original Draft	YES
4757996	26893605	PU	2	contributed to study design and interpretation of data	contributed to study design and interpretation of data	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Methodology|Resources	YES
3504796	23193432	Each of the authors	2	hereby transfers, assigns and otherwise conveys to the journal all right, title and interest in the work, including but not limited to any and all copyrights therein held by each undersigned author|hereby warrants, represents and covenants that each of the authors has read and approved the final manuscript or version of the work	hereby transfers, assigns and otherwise conveys to the journal all right, title and interest in the work, including but not limited to any and all copyrights therein held by each undersigned author	-	-	NO
3504796	23193432	Each of the authors	2	hereby transfers, assigns and otherwise conveys to the journal all right, title and interest in the work, including but not limited to any and all copyrights therein held by each undersigned author|hereby warrants, represents and covenants that each of the authors has read and approved the final manuscript or version of the work	hereby warrants, represents and covenants that each of the authors has read and approved the final manuscript or version of the work	Wrote the paper	Writing - Review & Editing	YES
4458515	26051165	DA	2	interpreted the data, revised and approved the final manuscript	interpreted the data, revised and approved the final manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4458515	26051165	FK	2	designed the study, conducted the initial analysis, interpreted the data, drafted the abstracts and final manuscript	designed the study, conducted the initial analysis, interpreted the data, drafted the abstracts and final manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
4458515	26051165	HS	2	was responsible for the cmis biobank, interpreted the data, revised and approved the final manuscript	was responsible for the cmis biobank, interpreted the data, revised and approved the final manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4458515	26051165	IB	2	analyzed and interpreted the data, revised and approved the final manuscript	analyzed and interpreted the data, revised and approved the final manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4458515	26051165	MB	2	collected the cmis clinical cohort data, interpreted the data, revised and approved the final manuscript	collected the cmis clinical cohort data, interpreted the data, revised and approved the final manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
4458515	26051165	NL	2	designed the original cmis cohort and collected the clinical data, interpreted the data, revised and approved the final manuscript	designed the original cmis cohort and collected the clinical data, interpreted the data, revised and approved the final manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
4458515	26051165	TD	2	analyzed the data, revised and approved the final manuscript	analyzed the data, revised and approved the final manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4458515	26051165	VL	2	collected the cmis clinical cohort data, interpreted the data, revised and approved the final manuscript	collected the cmis clinical cohort data, interpreted the data, revised and approved the final manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
5360583	28229909	A.C.	2	conducted research	conducted research	Performed the experiments	Investigation	YES
5360583	28229909	A.P.	2	conducted research	conducted research	Performed the experiments	Investigation	YES
5360583	28229909	All authors	2	contributed to data analysis and manuscript preparation	contributed to data analysis and manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5360583	28229909	E.S.	2	conducted research	conducted research	Performed the experiments	Investigation	YES
5360583	28229909	G.K.	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5360583	28229909	M.R.	2	conducted research	conducted research	Performed the experiments	Investigation	YES
5360583	28229909	M.S.	2	conducted research	conducted research	Performed the experiments	Investigation	YES
5360583	28229909	M.Z.	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5360583	28229909	P.B.	2	conceived the project|wrote the manuscript|conducted research	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5360583	28229909	P.B.	2	conceived the project|wrote the manuscript|conducted research	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5360583	28229909	P.B.	2	conceived the project|wrote the manuscript|conducted research	conducted research	Performed the experiments	Investigation	YES
5360583	28229909	P.R.	2	conceived the project|wrote the manuscript|conducted research	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5360583	28229909	P.R.	2	conceived the project|wrote the manuscript|conducted research	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5360583	28229909	P.R.	2	conceived the project|wrote the manuscript|conducted research	conducted research	Performed the experiments	Investigation	YES
5360583	28229909	S.B.	2	conducted research	conducted research	Performed the experiments	Investigation	YES
5419343	28970394	Agnieska Skowron	2	helped with distribution of the survey	helped with distribution of the survey	Performed the experiments	Investigation	YES
5419343	28970394	Annie Marcincal	2	helped with distribution of the survey	helped with distribution of the survey	Performed the experiments	Investigation	YES
5419343	28970394	Antonio Sanchez Pozo	2	developed the questionnaire|helped with distribution of the survey|provided useful criticism and suggestions during revision of the manuscript	developed the questionnaire	-	-	NO
5419343	28970394	Antonio Sanchez Pozo	2	developed the questionnaire|helped with distribution of the survey|provided useful criticism and suggestions during revision of the manuscript	helped with distribution of the survey	Performed the experiments	Investigation	YES
5419343	28970394	Antonio Sanchez Pozo	2	developed the questionnaire|helped with distribution of the survey|provided useful criticism and suggestions during revision of the manuscript	provided useful criticism and suggestions during revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5419343	28970394	Borut Bozic	2	helped with distribution of the survey	helped with distribution of the survey	Performed the experiments	Investigation	YES
5419343	28970394	Constantin Mircioiu	2	played a major role in the conception of the statistical analyses|checked and recalculated all the data|played a major part in the writing and revision of the manuscript	played a major role in the conception of the statistical analyses	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
5419343	28970394	Constantin Mircioiu	2	played a major role in the conception of the statistical analyses|checked and recalculated all the data|played a major part in the writing and revision of the manuscript	checked and recalculated all the data	Analyzed the data	Data curation|Formal analysis	YES
5419343	28970394	Constantin Mircioiu	2	played a major role in the conception of the statistical analyses|checked and recalculated all the data|played a major part in the writing and revision of the manuscript	played a major part in the writing and revision of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5419343	28970394	Daisy Volmer	2	provided useful criticism and suggestions during revision of the manuscript	provided useful criticism and suggestions during revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5419343	28970394	Dimitrios Rekkas	2	developed the questionnaire|helped with distribution of the survey|provided useful criticism and suggestions during revision of the manuscript	developed the questionnaire	-	-	NO
5419343	28970394	Dimitrios Rekkas	2	developed the questionnaire|helped with distribution of the survey|provided useful criticism and suggestions during revision of the manuscript	helped with distribution of the survey	Performed the experiments	Investigation	YES
5419343	28970394	Dimitrios Rekkas	2	developed the questionnaire|helped with distribution of the survey|provided useful criticism and suggestions during revision of the manuscript	provided useful criticism and suggestions during revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5419343	28970394	EAHP	2	provided comments from the perspective of hospital pharmacy practice|assured the distribution of the survey to their members	provided comments from the perspective of hospital pharmacy practice	-	-	NO
5419343	28970394	EAHP	2	provided comments from the perspective of hospital pharmacy practice|assured the distribution of the survey to their members	assured the distribution of the survey to their members	Performed the experiments	Investigation	YES
5419343	28970394	Ian Bates	2	played a major part in the writing and revision of the manuscript|suggested many useful modifications to the manuscript concerning the analysis and interpretation of the data and other aspects	played a major part in the writing and revision of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5419343	28970394	Ian Bates	2	played a major part in the writing and revision of the manuscript|suggested many useful modifications to the manuscript concerning the analysis and interpretation of the data and other aspects	suggested many useful modifications to the manuscript concerning the analysis and interpretation of the data and other aspects	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5419343	28970394	Jeffrey Atkinson	2	designed, constructed, ran and analysed the survey and wrote the paper	designed, constructed, ran and analysed the survey and wrote the paper	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5419343	28970394	Jouni Hirvonen	2	helped with distribution of the survey	helped with distribution of the survey	Performed the experiments	Investigation	YES
5419343	28970394	Keith A. Wilson	2	provided useful criticism and suggestions during revision of the manuscript	provided useful criticism and suggestions during revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5419343	28970394	Kristien De Paepe	2	ran the phar-qa consortium|provided useful criticism and suggestions during revision of the manuscript	ran the phar-qa consortium	Performed the experiments	Investigation	YES
5419343	28970394	Kristien De Paepe	2	ran the phar-qa consortium|provided useful criticism and suggestions during revision of the manuscript	provided useful criticism and suggestions during revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5419343	28970394	Richard Price	2	provided useful criticism and suggestions during revision of the manuscript	provided useful criticism and suggestions during revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5419343	28970394	Roxana Sandulovici	2	checked and recalculated all the data	checked and recalculated all the data	Analyzed the data	Data curation|Formal analysis	YES
4706565	26858834	Dr Broadbent	2	assisted in data analysis and interpretation	assisted in data analysis and interpretation	Analyzed the data	Formal analysis	YES
4706565	26858834	Mr Dolan	2	wrote up the final study report	wrote up the final study report	Wrote the paper	Writing - Original Draft	YES
5219701	28061752	CPS	2	conceived of, and designed this study, performed the statistical analysis, and drafted the manuscript	conceived of, and designed this study, performed the statistical analysis, and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
5219701	28061752	RB	2	participated in the design of the study and helped draft the manuscript	participated in the design of the study and helped draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5219701	28061752	RTN	2	participated in the design of the study and helped draft the manuscript	participated in the design of the study and helped draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5219701	28061752	RTP	2	studies, respectively, whose samples were used for this analysis	studies, respectively, whose samples were used for this analysis	Analyzed the data	Formal analysis	YES
5219701	28061752	SJT	2	participated in the design of the study and helped draft the manuscript	participated in the design of the study and helped draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5219701	28061752	VC	2	carried out quality control and normalization of the microarray data	carried out quality control and normalization of the microarray data	Performed the experiments	Investigation|Validation	YES
5219701	28061752	ZH	2	carried out quality control and normalization of the microarray data	carried out quality control and normalization of the microarray data	Performed the experiments	Investigation|Validation	YES
5508026	28751902	AD	1	Performed the experiment	Performed the experiment	Performed the experiments	Investigation	YES
5508026	28751902	BJ	1	Conceptualized, conceived, and designed the experiments	Conceptualized, conceived, and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5508026	28751902	JK	1	Performed the experiment|Data analysis	Performed the experiment	Performed the experiments	Investigation	YES
5508026	28751902	JK	1	Performed the experiment|Data analysis	Data analysis	Analyzed the data	Formal analysis	YES
5508026	28751902	MH	1	Performed the experiment	Performed the experiment	Performed the experiments	Investigation	YES
5508026	28751902	MR	1	Conceptualized, conceived, and designed the experiments|Data analysis|Manuscript preparation	Conceptualized, conceived, and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5508026	28751902	MR	1	Conceptualized, conceived, and designed the experiments|Data analysis|Manuscript preparation	Data analysis	Analyzed the data	Formal analysis	YES
5508026	28751902	MR	1	Conceptualized, conceived, and designed the experiments|Data analysis|Manuscript preparation	Manuscript preparation	Wrote the paper	Writing - Original Draft	YES
5508026	28751902	PU	1	Performed the experiment|Data analysis	Performed the experiment	Performed the experiments	Investigation	YES
5508026	28751902	PU	1	Performed the experiment|Data analysis	Data analysis	Analyzed the data	Formal analysis	YES
4404137	25894199	GQC	PLoS5	Contributed unpublished reagents/analytic tools	Contributed unpublished reagents/analytic tools	Contributed reagents/materials/analysis tools	Resources	YES
4404137	25894199	HY	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4404137	25894199	JL	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404137	25894199	JWL	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4404137	25894199	LXC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404137	25894199	LXC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404137	25894199	LXC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404137	25894199	MX	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4404137	25894199	SMM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4404137	25894199	SMM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404137	25894199	WHZ	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404137	25894199	YFL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404137	25894199	YFL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404137	25894199	YFL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404137	25894199	YY	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404137	25894199	ZLQ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404137	25894199	ZLQ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404137	25894199	ZLQ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4768327	26925155	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4768327	26925155	All the authors	2	contributed to redaction of the article	contributed to redaction of the article	-	-	NO
4768327	26925155	DC	2	wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
4768327	26925155	DN	2	helped for the writing and translation of the article	helped for the writing and translation of the article	Wrote the paper	Writing - Original Draft	YES
4768327	26925155	ED	2	helped for the writing and translation of the article	helped for the writing and translation of the article	Wrote the paper	Writing - Original Draft	YES
4768327	26925155	GC	2	wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
4768327	26925155	JB	2	collected the data	collected the data	Performed the experiments	Investigation	YES
4768327	26925155	LJ	2	collected the data	collected the data	Performed the experiments	Investigation	YES
4768327	26925155	MKG	2	collected the data	collected the data	Performed the experiments	Investigation	YES
4461747	26058983	DMT	2	critically revised the manuscript for important intellectual content	critically revised the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4461747	26058983	FGF	2	conceptualized the design of the study, developed data collection tools and oversaw study implementation|critically revised the manuscript for important intellectual content	conceptualized the design of the study, developed data collection tools and oversaw study implementation	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology|Supervision	YES
4461747	26058983	FGF	2	conceptualized the design of the study, developed data collection tools and oversaw study implementation|critically revised the manuscript for important intellectual content	critically revised the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4461747	26058983	HT	2	assisted with staff training and supervision|critically revised the manuscript for important intellectual content	assisted with staff training and supervision	-	Supervision	YES
4461747	26058983	HT	2	assisted with staff training and supervision|critically revised the manuscript for important intellectual content	critically revised the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4461747	26058983	MPF	2	conceptualized the design of the study, developed data collection tools and oversaw study implementation	conceptualized the design of the study, developed data collection tools and oversaw study implementation	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology|Supervision	YES
4461747	26058983	RN	2	conducted data analysis and drafted the original manuscript	conducted data analysis and drafted the original manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4461747	26058983	TD	2	conceptualized the design of the study, developed data collection tools and oversaw study implementation|critically revised the manuscript for important intellectual content	conceptualized the design of the study, developed data collection tools and oversaw study implementation	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology|Supervision	YES
4461747	26058983	TD	2	conceptualized the design of the study, developed data collection tools and oversaw study implementation|critically revised the manuscript for important intellectual content	critically revised the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4706569	26858833	AEF	CRediT	Study design|Data analysis|Writing|Supervision	Study design	Conceived and designed the experiments	Methodology	YES
4706569	26858833	AEF	CRediT	Study design|Data analysis|Writing|Supervision	Data analysis	Analyzed the data	Formal analysis	YES
4706569	26858833	AEF	CRediT	Study design|Data analysis|Writing|Supervision	Writing	Wrote the paper	-	YES
4706569	26858833	AEF	CRediT	Study design|Data analysis|Writing|Supervision	Supervision	-	Supervision	YES
4706569	26858833	AG	CRediT	Writing|Supervision	Writing	Wrote the paper	-	YES
4706569	26858833	AG	CRediT	Writing|Supervision	Supervision	-	Supervision	YES
4706569	26858833	JB	CRediT	Data collection|Data analysis	Data collection	Performed the experiments	Investigation	YES
4706569	26858833	JB	CRediT	Data collection|Data analysis	Data analysis	Analyzed the data	Formal analysis	YES
4706569	26858833	KS	CRediT	Data collection|Data analysis|Writing	Data collection	Performed the experiments	Investigation	YES
4706569	26858833	KS	CRediT	Data collection|Data analysis|Writing	Data analysis	Analyzed the data	Formal analysis	YES
4706569	26858833	KS	CRediT	Data collection|Data analysis|Writing	Writing	Wrote the paper	-	YES
4706569	26858833	NF	CRediT	Data collection|Data analysis|Writing	Data collection	Performed the experiments	Investigation	YES
4706569	26858833	NF	CRediT	Data collection|Data analysis|Writing	Data analysis	Analyzed the data	Formal analysis	YES
4706569	26858833	NF	CRediT	Data collection|Data analysis|Writing	Writing	Wrote the paper	-	YES
4706569	26858833	NJW	CRediT	Supervision	Supervision	-	Supervision	YES
5419344	28970389	Janine Traulsen	2	was involved in designing the study, analyzing the data, and revising the manuscript	was involved in designing the study, analyzing the data, and revising the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
5419344	28970389	Rasmus Borup	2	was involved in designing the study, conducting the interviews and gathering documents, performing analysis of the data, and writing the manuscript	was involved in designing the study, conducting the interviews and gathering documents, performing analysis of the data, and writing the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5219712	28061743	MS	2	data analysis, and wrote the manuscript	data analysis, and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5219712	28061743	RM	2	designed the research, conducted the experiments	designed the research, conducted the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4706571	26858831	Assistant Husam Majeed	7	Participated substantially in conception, design of the study, collection of data, preoperative & postoperative check of the vocal cords	Participated substantially in conception, design of the study, collection of data, preoperative & postoperative check of the vocal cords	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
4706571	26858831	Assistant Jawad Kadhim	7	Participated substantially in conception, design, surgical performance, collection and analysis of data	Participated substantially in conception, design, surgical performance, collection and analysis of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation	YES
4706571	26858831	S. Al-Dhahiry	7	Participated substantially in conception, design, surgical performance, collection and analysis of data	Participated substantially in conception, design, surgical performance, collection and analysis of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation	YES
4404138	25894229	ANL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404138	25894229	ANL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404138	25894229	ANL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404138	25894229	ANL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404138	25894229	ANL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404138	25894229	RJC	PLoS5	Performed the experiments|Analyzed the data|Edited the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4404138	25894229	RJC	PLoS5	Performed the experiments|Analyzed the data|Edited the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4404138	25894229	RJC	PLoS5	Performed the experiments|Analyzed the data|Edited the manuscript	Edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
4404138	25894229	SJS	PLoS5	Performed the experiments|Analyzed the data|Edited the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4404138	25894229	SJS	PLoS5	Performed the experiments|Analyzed the data|Edited the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4404138	25894229	SJS	PLoS5	Performed the experiments|Analyzed the data|Edited the manuscript	Edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
4404138	25894229	TD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Edited the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404138	25894229	TD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Edited the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4404138	25894229	TD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Edited the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4404138	25894229	TD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Edited the manuscript	Edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5405164	28302457	AT	2	performed statistical analysis	performed statistical analysis	Analyzed the data	Formal analysis	YES
5419345	28970391	D.V.	2	developed the survey instrument, participated in data analysis and writing the manuscript	developed the survey instrument, participated in data analysis and writing the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5419345	28970391	M.G.	2	participated in the development of survey instrument and writing the manuscript, conducted survey and performed data analysis	participated in the development of survey instrument and writing the manuscript, conducted survey and performed data analysis	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5219731	28061746	APR	PLoS52	designed the study|funded the study	designed the study	Conceived and designed the experiments	Methodology	YES
5219731	28061746	APR	PLoS52	designed the study|funded the study	funded the study	-	Funding acquisition	YES
5219731	28061746	All authors	PLoS52	contributed to manuscript writing and editing	contributed to manuscript writing and editing	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5219731	28061746	EZ	PLoS52	collected the data|analysed the data	collected the data	Performed the experiments	Investigation	YES
5219731	28061746	EZ	PLoS52	collected the data|analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
5219731	28061746	JM	PLoS52	collected the data	collected the data	Performed the experiments	Investigation	YES
5219731	28061746	LCB	PLoS52	designed the study|provided the samples|collected the data	designed the study	Conceived and designed the experiments	Methodology	YES
5219731	28061746	LCB	PLoS52	designed the study|provided the samples|collected the data	provided the samples	Contributed reagents/materials/analysis tools	Resources	YES
5219731	28061746	LCB	PLoS52	designed the study|provided the samples|collected the data	collected the data	Performed the experiments	Investigation	YES
5219731	28061746	LO	PLoS52	analysed the data|completed the statistical analysis	analysed the data	Analyzed the data	Formal analysis	YES
5219731	28061746	LO	PLoS52	analysed the data|completed the statistical analysis	completed the statistical analysis	Analyzed the data	Formal analysis	YES
5219731	28061746	MDG	PLoS52	designed the study|funded the study	designed the study	Conceived and designed the experiments	Methodology	YES
5219731	28061746	MDG	PLoS52	designed the study|funded the study	funded the study	-	Funding acquisition	YES
5219731	28061746	SL	PLoS52	designed the study|analysed the data|completed the statistical analysis|funded the study	designed the study	Conceived and designed the experiments	Methodology	YES
5219731	28061746	SL	PLoS52	designed the study|analysed the data|completed the statistical analysis|funded the study	analysed the data	Analyzed the data	Formal analysis	YES
5219731	28061746	SL	PLoS52	designed the study|analysed the data|completed the statistical analysis|funded the study	completed the statistical analysis	Analyzed the data	Formal analysis	YES
5219731	28061746	SL	PLoS52	designed the study|analysed the data|completed the statistical analysis|funded the study	funded the study	-	Funding acquisition	YES
5508029	28751903	All authors	2	read and approved the manuscript	read and approved the manuscript	-	-	NO
5508029	28751903	FR	2	performed bioinformatics analysis|conceived the study, interpreted the results and wrote the paper	performed bioinformatics analysis	Performed the experiments	Formal analysis|Investigation	YES
5508029	28751903	FR	2	performed bioinformatics analysis|conceived the study, interpreted the results and wrote the paper	conceived the study, interpreted the results and wrote the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
5508029	28751903	FV	2	conceived the study, interpreted the results and wrote the paper	conceived the study, interpreted the results and wrote the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
5508029	28751903	JR	2	conceived the study, interpreted the results and wrote the paper	conceived the study, interpreted the results and wrote the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
5508029	28751903	MR	2	carried out experimental work	carried out experimental work	Performed the experiments	Investigation	YES
4463476	26066346	APD	1	Study design and implementation|Manuscript drafting and final approval	Study design and implementation	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4463476	26066346	APD	1	Study design and implementation|Manuscript drafting and final approval	Manuscript drafting and final approval	Wrote the paper	Writing - Original Draft	YES
4463476	26066346	DC	1	Study design and implementation|Manuscript drafting and final approval	Study design and implementation	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4463476	26066346	DC	1	Study design and implementation|Manuscript drafting and final approval	Manuscript drafting and final approval	Wrote the paper	Writing - Original Draft	YES
4463476	26066346	HH	1	Study design and implementation|Manuscript drafting and final approval	Study design and implementation	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4463476	26066346	HH	1	Study design and implementation|Manuscript drafting and final approval	Manuscript drafting and final approval	Wrote the paper	Writing - Original Draft	YES
4463476	26066346	JL	1	Study design and implementation|Data analysis|Manuscript drafting and final approval	Study design and implementation	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4463476	26066346	JL	1	Study design and implementation|Data analysis|Manuscript drafting and final approval	Data analysis	Analyzed the data	Formal analysis	YES
4463476	26066346	JL	1	Study design and implementation|Data analysis|Manuscript drafting and final approval	Manuscript drafting and final approval	Wrote the paper	Writing - Original Draft	YES
4463476	26066346	PMA	1	Study design and implementation|Manuscript drafting and final approval	Study design and implementation	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4463476	26066346	PMA	1	Study design and implementation|Manuscript drafting and final approval	Manuscript drafting and final approval	Wrote the paper	Writing - Original Draft	YES
4463476	26066346	RS	1	Study design and implementation|Manuscript drafting and final approval	Study design and implementation	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4463476	26066346	RS	1	Study design and implementation|Manuscript drafting and final approval	Manuscript drafting and final approval	Wrote the paper	Writing - Original Draft	YES
4463476	26066346	RY	1	Data analysis|Manuscript drafting and final approval	Data analysis	Analyzed the data	Formal analysis	YES
4463476	26066346	RY	1	Data analysis|Manuscript drafting and final approval	Manuscript drafting and final approval	Wrote the paper	Writing - Original Draft	YES
4463476	26066346	SB	1	Study design and implementation|Manuscript drafting and final approval	Study design and implementation	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4463476	26066346	SB	1	Study design and implementation|Manuscript drafting and final approval	Manuscript drafting and final approval	Wrote the paper	Writing - Original Draft	YES
4463476	26066346	TC	1	Study design and implementation|Manuscript drafting and final approval	Study design and implementation	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4463476	26066346	TC	1	Study design and implementation|Manuscript drafting and final approval	Manuscript drafting and final approval	Wrote the paper	Writing - Original Draft	YES
4465680	26114112	Tongqing Yao	2	contributed equally to the project	contributed equally to the project	-	-	NO
4465680	26114112	Xian Jin	2	contributed equally to the project	contributed equally to the project	-	-	NO
4782509	26958071	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4782509	26958071	GR	2	were responsible for experimental design and data analysis, and assisted with project conceptualisation	were responsible for experimental design and data analysis, and assisted with project conceptualisation	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation|Methodology	YES
4782509	26958071	HIV	2	prevention, treatment and care	prevention, treatment and care	-	-	NO
4782509	26958071	HW	2	were responsible for experimental design and data analysis, and assisted with project conceptualisation	were responsible for experimental design and data analysis, and assisted with project conceptualisation	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation|Methodology	YES
4782509	26958071	NA	2	were responsible for experimental design and data analysis, and assisted with project conceptualisation	were responsible for experimental design and data analysis, and assisted with project conceptualisation	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation|Methodology	YES
4782509	26958071	RS	2	were responsible for experimental design and data analysis, and assisted with project conceptualisation	were responsible for experimental design and data analysis, and assisted with project conceptualisation	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation|Methodology	YES
4782509	26958071	ZG	2	is the lead author and was responsible for project conceptualisation|wrote the manuscript with intellectual input from authors	is the lead author and was responsible for project conceptualisation	Conceived and designed the experiments	Conceptualization	YES
4782509	26958071	ZG	2	is the lead author and was responsible for project conceptualisation|wrote the manuscript with intellectual input from authors	wrote the manuscript with intellectual input from authors	Wrote the paper	Writing - Original Draft	YES
4404139	25893988	HJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404139	25893988	HJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404139	25893988	HJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404139	25893988	HJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404139	25893988	JD	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404139	25893988	JD	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404139	25893988	KB	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404139	25893988	LD	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404139	25893988	OF	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404139	25893988	OF	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404139	25893988	OF	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4708073	26862396	D Feron-Boothe	1	Collection	Collection	-	-	NO
4708073	26862396	N Meeks-Aitken	1	Collection	Collection	-	-	NO
5419346	28970390	Anne Croker	2	contributed to the conception and design of the work, the interpretation of data and drafting of the paper	contributed to the conception and design of the work, the interpretation of data and drafting of the paper	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Resources|Writing - Original Draft	YES
5419346	28970390	Karin Fisher	2	contributed to the design of the research and critical revision of the paper	contributed to the design of the research and critical revision of the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5419346	28970390	Sonja Littlejohns	2	contributed to the critical revision of the paper	contributed to the critical revision of the paper	Wrote the paper	Writing - Review & Editing	YES
5419346	28970390	Tony Smith	2	contributed to the design of the research and critical revision of the paper	contributed to the design of the research and critical revision of the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5219736	28061749	AB	2	wrote the program, designed the experiments, wrote the manuscript, and discussed the design of the program and the results with the other contributors of the article	wrote the program, designed the experiments, wrote the manuscript, and discussed the design of the program and the results with the other contributors of the article	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Methodology|Software|Writing - Original Draft	YES
5219736	28061749	AS	2	performed the experiments and reviewed the manuscript	performed the experiments and reviewed the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5219736	28061749	DH	2	reviewed the manuscript and contributed to the discussion of the experiments	reviewed the manuscript and contributed to the discussion of the experiments	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5219736	28061749	DZ	2	reviewed the manuscript and contributed to the discussion of the experiments	reviewed the manuscript and contributed to the discussion of the experiments	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5405165	28396013	A.L.B.	2	helped with experiments	helped with experiments	Performed the experiments	Investigation	YES
5405165	28396013	A.P.	2	helped during experiments	helped during experiments	Performed the experiments	Investigation	YES
5405165	28396013	F.A.	2	performed the in vitro study with pdes1-5	performed the in vitro study with pdes1-5	Performed the experiments	Investigation	YES
5405165	28396013	H.K.	2	helped with experiments|performed docking of srt1720 to the pde3b active site	helped with experiments	Performed the experiments	Investigation	YES
5405165	28396013	H.K.	2	helped with experiments|performed docking of srt1720 to the pde3b active site	performed docking of srt1720 to the pde3b active site	Performed the experiments	Investigation	YES
5405165	28396013	J.H.C.	2	designed and supervised the study, analyzed the data and wrote the manuscript	designed and supervised the study, analyzed the data and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Supervision|Writing - Original Draft	YES
5405165	28396013	J.H.U.	2	helped with experiments	helped with experiments	Performed the experiments	Investigation	YES
5405165	28396013	J.R.	2	generated muscle specific sirt1ko mice	generated muscle specific sirt1ko mice	Performed the experiments	Investigation	YES
5405165	28396013	M.K.K.	2	designed and supervised the study, analyzed the data and wrote the manuscript	designed and supervised the study, analyzed the data and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Supervision|Writing - Original Draft	YES
5405165	28396013	S.S.	2	helped during experiments	helped during experiments	Performed the experiments	Investigation	YES
5405165	28396013	V.S.	2	generated muscle specific sirt1ko mice	generated muscle specific sirt1ko mice	Performed the experiments	Investigation	YES
5405165	28396013	X.F.	2	generated muscle specific sirt1ko mice	generated muscle specific sirt1ko mice	Performed the experiments	Investigation	YES
5405165	28396013	X.X.	2	helped with experiments	helped with experiments	Performed the experiments	Investigation	YES
4468054	26077644	AL	2	contributed to data analysis and manuscript comments	contributed to data analysis and manuscript comments	Analyzed the data	Formal analysis	YES
4468054	26077644	BB	2	contributed to vision, design, implementation, data analysis and manuscript writing	contributed to vision, design, implementation, data analysis and manuscript writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft	YES
4468054	26077644	BN	2	contributed to design, implementation and manuscript comments	contributed to design, implementation and manuscript comments	Conceived and designed the experiments|Performed the experiments	Investigation	YES
4468054	26077644	JB	2	contributed to vision, design, implementation, data analysis and manuscript writing	contributed to vision, design, implementation, data analysis and manuscript writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft	YES
4468054	26077644	LD	2	contributed to data analysis and manuscript comments	contributed to data analysis and manuscript comments	Analyzed the data	Formal analysis	YES
4468054	26077644	OM	2	contributed to design, data analysis and manuscript writing	contributed to design, data analysis and manuscript writing	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
5508101	28751895	AD	2	conducted all experiments and drafted the manuscript	conducted all experiments and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5508101	28751895	AT	2	conceived and designed the study, guided data analysis and interpretation, participated in drafting and correcting the manuscript critically and gave the final approval of the version to be published	conceived and designed the study, guided data analysis and interpretation, participated in drafting and correcting the manuscript critically and gave the final approval of the version to be published	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
5508101	28751895	CB	2	helped in development, advancement and phenotyping of mapping populations	helped in development, advancement and phenotyping of mapping populations	Performed the experiments	Investigation	YES
5508101	28751895	HU	2	helped in development, advancement and phenotyping of mapping populations	helped in development, advancement and phenotyping of mapping populations	Performed the experiments	Investigation	YES
5508101	28751895	PS	2	helped in development, advancement and phenotyping of mapping populations	helped in development, advancement and phenotyping of mapping populations	Performed the experiments	Investigation	YES
5508101	28751895	RK	2	helped in development, advancement and phenotyping of mapping populations	helped in development, advancement and phenotyping of mapping populations	Performed the experiments	Investigation	YES
5508101	28751895	RS	2	conducted all experiments and drafted the manuscript	conducted all experiments and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5508101	28751895	SP	2	conceived and designed the study, guided data analysis and interpretation, participated in drafting and correcting the manuscript critically and gave the final approval of the version to be published	conceived and designed the study, guided data analysis and interpretation, participated in drafting and correcting the manuscript critically and gave the final approval of the version to be published	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
5508101	28751895	ST	2	helped in development, advancement and phenotyping of mapping populations	helped in development, advancement and phenotyping of mapping populations	Performed the experiments	Investigation	YES
5508101	28751895	UB	2	conducted all experiments and drafted the manuscript	conducted all experiments and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4404140	25893432	BJ	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404140	25893432	CA	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404140	25893432	KQ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404140	25893432	LG	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4404140	25893432	LZ	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404140	25893432	RH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404140	25893432	RH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404140	25893432	RH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404140	25893432	RH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404140	25893432	SW	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4404140	25893432	XZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5219742	28061745	CYW	2	participated in some statistical analyses	participated in some statistical analyses	Analyzed the data	Formal analysis	YES
5219742	28061745	HFY	2	are helpful for materials collection	are helpful for materials collection	-	-	NO
5219742	28061745	QZL	2	prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5219742	28061745	SCG	2	prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5219742	28061745	WJ	2	participated in some statistical analyses	participated in some statistical analyses	Analyzed the data	Formal analysis	YES
5219742	28061745	WXS	2	participated in some statistical analyses	participated in some statistical analyses	Analyzed the data	Formal analysis	YES
5219742	28061745	YLA	2	are helpful for materials collection	are helpful for materials collection	-	-	NO
5419347	28970385	Agnieska Skowron	2	helped with distribution of the survey	helped with distribution of the survey	Performed the experiments	Investigation	YES
5419347	28970385	Annie Marcincal	2	helped with distribution of the survey	helped with distribution of the survey	Performed the experiments	Investigation	YES
5419347	28970385	Antonio Sanchez Pozo	2	developed the questionnaire|helped with distribution of the survey|provided useful criticism and suggestions during revision of the manuscript	developed the questionnaire	-	-	NO
5419347	28970385	Antonio Sanchez Pozo	2	developed the questionnaire|helped with distribution of the survey|provided useful criticism and suggestions during revision of the manuscript	helped with distribution of the survey	Performed the experiments	Investigation	YES
5419347	28970385	Antonio Sanchez Pozo	2	developed the questionnaire|helped with distribution of the survey|provided useful criticism and suggestions during revision of the manuscript	provided useful criticism and suggestions during revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5419347	28970385	Borut Bozic	2	helped with distribution of the survey	helped with distribution of the survey	Performed the experiments	Investigation	YES
5419347	28970385	Constantin Mircioiu	2	played a major role in the statistical analyses of the data	played a major role in the statistical analyses of the data	Analyzed the data	Formal analysis	YES
5419347	28970385	Daisy Volmer	2	provided useful criticism and suggestions during revision of the manuscript	provided useful criticism and suggestions during revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5419347	28970385	Dimitrios Rekkas	2	developed the questionnaire|helped with distribution of the survey	developed the questionnaire	-	-	NO
5419347	28970385	Dimitrios Rekkas	2	developed the questionnaire|helped with distribution of the survey	helped with distribution of the survey	Performed the experiments	Investigation	YES
5419347	28970385	Jamie Wilkinson	2	helped distribute the survey	helped distribute the survey	Performed the experiments	Investigation	YES
5419347	28970385	Jeffrey Atkinson	2	designed, constructed, ran and analyzed the survey and wrote the paper	designed, constructed, ran and analyzed the survey and wrote the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5419347	28970385	Jouni Hirvonen	2	helped with distribution of the survey	helped with distribution of the survey	Performed the experiments	Investigation	YES
5419347	28970385	Keith Wilson	2	provided useful criticism and suggestions during revision of the manuscript	provided useful criticism and suggestions during revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5419347	28970385	Kristien De Paepe	2	ran the phar-qa consortium|provided useful criticism and suggestions during revision of the manuscript	ran the phar-qa consortium	Performed the experiments	Investigation	YES
5419347	28970385	Kristien De Paepe	2	ran the phar-qa consortium|provided useful criticism and suggestions during revision of the manuscript	provided useful criticism and suggestions during revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4799629	26997965	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4799629	26997965	K. As	2	expert in the hiv-1-nk cell niche	expert in the hiv-1-nk cell niche	Performed the experiments	Investigation	YES
4799629	26997965	WJ	2	also contributed in sharing of insights and concerning the content of the review	also contributed in sharing of insights and concerning the content of the review	-	-	NO
3508555	23213299	L. Xu	2	contributed equally to this work	contributed equally to this work	-	-	NO
3508555	23213299	X. Liu	2	contributed equally to this work	contributed equally to this work	-	-	NO
3508555	23213299	Y. Huang	2	contributed equally to this work	contributed equally to this work	-	-	NO
4710706	26865977	DS	7	data analysis, revision	data analysis, revision	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4710706	26865977	DZP	7	data collection, data analysis	data collection, data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4710706	26865977	EK	7	data collection, data analysis	data collection, data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4710706	26865977	KTT	7	study design, data analysis, writing	study design, data analysis, writing	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology	YES
4710706	26865977	VV	7	data collection	data collection	Performed the experiments	Investigation	YES
4465819	26114113	Alexander Bolshoy	2	led the project, designed the framework, and wrote the paper	led the project, designed the framework, and wrote the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4465819	26114113	Jennifer Dien Bard	2	provided clinical insight and participated in paper preparation	provided clinical insight and participated in paper preparation	-	-	NO
4465819	26114113	Tatiana Tatarinova	2	curated the datasets, implemented the algorithm, carried out the comparison of algorithms, and wrote the paper	curated the datasets, implemented the algorithm, carried out the comparison of algorithms, and wrote the paper	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Data curation|Investigation|Software|Writing - Original Draft	YES
4482814	26115688	PN	2	contributed with the clinical data and clinical input in the study and critical revision of the manuscript	contributed with the clinical data and clinical input in the study and critical revision of the manuscript	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Review & Editing	YES
4482814	26115688	SG	2	performed the laboratory and bioinformatics analysis	performed the laboratory and bioinformatics analysis	Performed the experiments	Formal analysis|Investigation	YES
4482814	26115688	UN	2	designed the study and wrote the first draft of the manuscript|performed the laboratory and bioinformatics analysis	designed the study and wrote the first draft of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4482814	26115688	UN	2	designed the study and wrote the first draft of the manuscript|performed the laboratory and bioinformatics analysis	performed the laboratory and bioinformatics analysis	Performed the experiments	Formal analysis|Investigation	YES
5509796	28769937	BB	2	contributed to their interpretation	contributed to their interpretation	Analyzed the data	Formal analysis	YES
5509796	28769937	CC	2	participated in the design of the study|contributed to their interpretation|wrote the manuscript	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
5509796	28769937	CC	2	participated in the design of the study|contributed to their interpretation|wrote the manuscript	contributed to their interpretation	Analyzed the data	Formal analysis	YES
5509796	28769937	CC	2	participated in the design of the study|contributed to their interpretation|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5509796	28769937	CL	2	performed the sugar content analysis	performed the sugar content analysis	Performed the experiments	Investigation	YES
5509796	28769937	HE	2	participated in the design of the study|contributed to their interpretation|wrote the manuscript	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
5509796	28769937	HE	2	participated in the design of the study|contributed to their interpretation|wrote the manuscript	contributed to their interpretation	Analyzed the data	Formal analysis	YES
5509796	28769937	HE	2	participated in the design of the study|contributed to their interpretation|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5509796	28769937	J-CB	2	helped cc performing plant cultivation, measurements and sample harvest in growth chamber	helped cc performing plant cultivation, measurements and sample harvest in growth chamber	Performed the experiments	Investigation	YES
5509796	28769937	JA	2	performed the evaluation of antioxidant activity and participated to the data analysis	performed the evaluation of antioxidant activity and participated to the data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5509796	28769937	LB	2	contributed to their interpretation	contributed to their interpretation	Analyzed the data	Formal analysis	YES
5509796	28769937	LM	2	participated in the design of the study	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
5509796	28769937	LT	2	helped cc performing plant cultivation, measurements and sample harvest in growth chamber	helped cc performing plant cultivation, measurements and sample harvest in growth chamber	Performed the experiments	Investigation	YES
5509796	28769937	LU	2	participated in the design of the study|wrote the manuscript	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
5509796	28769937	LU	2	participated in the design of the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5509796	28769937	YL	2	performed the evaluation of antioxidant activity and participated to the data analysis	performed the evaluation of antioxidant activity and participated to the data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5219757	28061806	DKG	2	supervised the project, helped interpret the analysis, and helped to draft the manuscript	supervised the project, helped interpret the analysis, and helped to draft the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Supervision|Writing - Original Draft	YES
5219757	28061806	YG	2	conceived the project, developed the method, analyzed the results, and drafted the manuscript	conceived the project, developed the method, analyzed the results, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
4404142	25894344	AR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404142	25894344	AR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404142	25894344	AR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404142	25894344	AR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404142	25894344	CCW	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404142	25894344	MR	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4404142	25894344	MR	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4404142	25894344	SS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404142	25894344	SS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404142	25894344	TS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4404142	25894344	TS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4802903	27006682	All authors	2	participated in the design of the study and manuscript preparation|read and approved the final manuscript	participated in the design of the study and manuscript preparation	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4802903	27006682	All authors	2	participated in the design of the study and manuscript preparation|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4802903	27006682	XW	2	performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
5405178	28400202	BW	PLoS52	designed the study|interpreted the data|commented and revised the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5405178	28400202	BW	PLoS52	designed the study|interpreted the data|commented and revised the manuscript	interpreted the data	Analyzed the data	Formal analysis	YES
5405178	28400202	BW	PLoS52	designed the study|interpreted the data|commented and revised the manuscript	commented and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5405178	28400202	CCL	PLoS52	conceived the study, obtained the funding to conduct it, and wrote the manuscript|designed the study|analysed the data|interpreted the data	conceived the study, obtained the funding to conduct it, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Funding acquisition|Investigation|Writing - Original Draft	YES
5405178	28400202	CCL	PLoS52	conceived the study, obtained the funding to conduct it, and wrote the manuscript|designed the study|analysed the data|interpreted the data	designed the study	Conceived and designed the experiments	Methodology	YES
5405178	28400202	CCL	PLoS52	conceived the study, obtained the funding to conduct it, and wrote the manuscript|designed the study|analysed the data|interpreted the data	analysed the data	Analyzed the data	Formal analysis	YES
5405178	28400202	CCL	PLoS52	conceived the study, obtained the funding to conduct it, and wrote the manuscript|designed the study|analysed the data|interpreted the data	interpreted the data	Analyzed the data	Formal analysis	YES
5405178	28400202	CNAP	PLoS52	analysed the data|interpreted the data|commented and revised the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
5405178	28400202	CNAP	PLoS52	analysed the data|interpreted the data|commented and revised the manuscript	interpreted the data	Analyzed the data	Formal analysis	YES
5405178	28400202	CNAP	PLoS52	analysed the data|interpreted the data|commented and revised the manuscript	commented and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5405178	28400202	DL	PLoS52	analysed the data|interpreted the data|commented and revised the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
5405178	28400202	DL	PLoS52	analysed the data|interpreted the data|commented and revised the manuscript	interpreted the data	Analyzed the data	Formal analysis	YES
5405178	28400202	DL	PLoS52	analysed the data|interpreted the data|commented and revised the manuscript	commented and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5405178	28400202	EV	PLoS52	interpreted the data|commented and revised the manuscript	interpreted the data	Analyzed the data	Formal analysis	YES
5405178	28400202	EV	PLoS52	interpreted the data|commented and revised the manuscript	commented and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5405178	28400202	HMP	PLoS52	commented and revised the manuscript	commented and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5405178	28400202	LMB	PLoS52	conceived the study, obtained the funding to conduct it, and wrote the manuscript|designed the study|interpreted the data	conceived the study, obtained the funding to conduct it, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Funding acquisition|Investigation|Writing - Original Draft	YES
5405178	28400202	LMB	PLoS52	conceived the study, obtained the funding to conduct it, and wrote the manuscript|designed the study|interpreted the data	designed the study	Conceived and designed the experiments	Methodology	YES
5405178	28400202	LMB	PLoS52	conceived the study, obtained the funding to conduct it, and wrote the manuscript|designed the study|interpreted the data	interpreted the data	Analyzed the data	Formal analysis	YES
5405178	28400202	PMS	PLoS52	designed the study|interpreted the data|commented and revised the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5405178	28400202	PMS	PLoS52	designed the study|interpreted the data|commented and revised the manuscript	interpreted the data	Analyzed the data	Formal analysis	YES
5405178	28400202	PMS	PLoS52	designed the study|interpreted the data|commented and revised the manuscript	commented and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5405178	28400202	SBH	PLoS52	interpreted the data|commented and revised the manuscript	interpreted the data	Analyzed the data	Formal analysis	YES
5405178	28400202	SBH	PLoS52	interpreted the data|commented and revised the manuscript	commented and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5405178	28400202	SKP	PLoS52	conceived the study, obtained the funding to conduct it, and wrote the manuscript|designed the study|analysed the data|interpreted the data	conceived the study, obtained the funding to conduct it, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Funding acquisition|Investigation|Writing - Original Draft	YES
5405178	28400202	SKP	PLoS52	conceived the study, obtained the funding to conduct it, and wrote the manuscript|designed the study|analysed the data|interpreted the data	designed the study	Conceived and designed the experiments	Methodology	YES
5405178	28400202	SKP	PLoS52	conceived the study, obtained the funding to conduct it, and wrote the manuscript|designed the study|analysed the data|interpreted the data	analysed the data	Analyzed the data	Formal analysis	YES
5405178	28400202	SKP	PLoS52	conceived the study, obtained the funding to conduct it, and wrote the manuscript|designed the study|analysed the data|interpreted the data	interpreted the data	Analyzed the data	Formal analysis	YES
5419348	28970381	Agneska Skowron	2	helped with distribution of the survey	helped with distribution of the survey	Performed the experiments	Investigation	YES
5419348	28970381	Annie Marcincal	2	helped with distribution of the survey	helped with distribution of the survey	Performed the experiments	Investigation	YES
5419348	28970381	Antonio Sanchez-Pozo	2	developed the questionnaire|helped with distribution of the survey|provided useful criticism and suggestions during revision of the manuscript	developed the questionnaire	-	-	NO
5419348	28970381	Antonio Sanchez-Pozo	2	developed the questionnaire|helped with distribution of the survey|provided useful criticism and suggestions during revision of the manuscript	helped with distribution of the survey	Performed the experiments	Investigation	YES
5419348	28970381	Antonio Sanchez-Pozo	2	developed the questionnaire|helped with distribution of the survey|provided useful criticism and suggestions during revision of the manuscript	provided useful criticism and suggestions during revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5419348	28970381	Borut Bozic	2	helped with distribution of the survey	helped with distribution of the survey	Performed the experiments	Investigation	YES
5419348	28970381	Constantin Mircioiu	2	played a major role in the statistical analyses of the data	played a major role in the statistical analyses of the data	Analyzed the data	Formal analysis	YES
5419348	28970381	Daisy Volmer	2	provided useful criticism and suggestions during revision of the manuscript	provided useful criticism and suggestions during revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5419348	28970381	Dimitri Rekkas	2	developed the questionnaire|helped with distribution of the survey	developed the questionnaire	-	-	NO
5419348	28970381	Dimitri Rekkas	2	developed the questionnaire|helped with distribution of the survey	helped with distribution of the survey	Performed the experiments	Investigation	YES
5419348	28970381	Jeffrey Atkinson	2	constructed, ran and analyzed the survey and wrote the paper	constructed, ran and analyzed the survey and wrote the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5419348	28970381	Jouni Hirvonen	2	helped with distribution of the survey	helped with distribution of the survey	Performed the experiments	Investigation	YES
5419348	28970381	Kristien De Paepe	2	ran the phar-qa consortium|provided useful criticism and suggestions during revision of the manuscript	ran the phar-qa consortium	Performed the experiments	Investigation	YES
5419348	28970381	Kristien De Paepe	2	ran the phar-qa consortium|provided useful criticism and suggestions during revision of the manuscript	provided useful criticism and suggestions during revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5419348	28970381	Sandra Hocevar	2	played a major role in distributing the survey to students	played a major role in distributing the survey to students	Performed the experiments	Investigation	YES
4710759	26865978	Ebral Yigit	5	contributed [1] [2] [3] Mehmet Babur contributed [1] [2] [3] Serdar Gumus contributed [1] [2] [3	contributed [1] [2] [3] Mehmet Babur contributed [1] [2] [3] Serdar Gumus contributed [1] [2] [3	-	-	NO
4710759	26865978	Yusuf Yagmur	5	operated the patient and contributed [1] the conception and design of the study	operated the patient and contributed [1] the conception and design of the study	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
5219783	28061742	AK	2	wrote the manuscript and software documentation together	wrote the manuscript and software documentation together	Contributed reagents/materials/analysis tools|Wrote the paper	Software|Writing - Original Draft	YES
5219783	28061742	DEIVA	2	implemented a prototype	implemented a prototype	Performed the experiments	Investigation	YES
5219783	28061742	JH	2	wrote the manuscript and software documentation together	wrote the manuscript and software documentation together	Contributed reagents/materials/analysis tools|Wrote the paper	Software|Writing - Original Draft	YES
5219783	28061742	PC	2	supervised the project	supervised the project	-	Supervision	YES
5219783	28061742	SPA	2	considerably extended its functionality	considerably extended its functionality	-	-	NO
4720711	26904189	Henk Van Rooyen	7	contributor and supervisor	contributor and supervisor	-	Supervision	YES
4720711	26904189	Ryo Mizumoto	7	first author	first author	-	-	NO
5509804	28769941	DL	4	The manuscript was prepared by	The manuscript was prepared by	Wrote the paper	Writing - Original Draft	YES
5509804	28769941	DX	4	Research was performed by|The manuscript was prepared by	Research was performed by	Performed the experiments	Investigation	YES
5509804	28769941	DX	4	Research was performed by|The manuscript was prepared by	The manuscript was prepared by	Wrote the paper	Writing - Original Draft	YES
5509804	28769941	TK	4	Research was designed by|Research was performed by|The manuscript was prepared by	Research was designed by	Conceived and designed the experiments	-	YES
5509804	28769941	TK	4	Research was designed by|Research was performed by|The manuscript was prepared by	Research was performed by	Performed the experiments	Investigation	YES
5509804	28769941	TK	4	Research was designed by|Research was performed by|The manuscript was prepared by	The manuscript was prepared by	Wrote the paper	Writing - Original Draft	YES
4404143	25894575	AB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404143	25894575	AB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404143	25894575	AB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404143	25894575	AC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4404143	25894575	AL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4404143	25894575	AW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404143	25894575	AW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4404143	25894575	AW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4404143	25894575	CB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4404143	25894575	CB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4404143	25894575	CB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404143	25894575	EL	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404143	25894575	EL	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404143	25894575	KP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4404143	25894575	LS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404143	25894575	LS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404143	25894575	LS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404143	25894575	LS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404143	25894575	LS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404143	25894575	MD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404143	25894575	MD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404143	25894575	MD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404143	25894575	RC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4404143	25894575	WZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404143	25894575	WZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404143	25894575	WZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404143	25894575	WZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5419349	28970388	All	2	study authors contributed to the preparation of this manuscript	study authors contributed to the preparation of this manuscript	Wrote the paper	Writing - Original Draft	YES
5419349	28970388	Grainne Cousins	2	conceived and designed the project	conceived and designed the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5419349	28970388	Martin Henman	2	conceived and designed the project	conceived and designed the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5419349	28970388	Mary-Claire Kennedy	2	conceived and designed the project	conceived and designed the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
4486418	26130226	JPR	2	designed the study, contributed significantly to the review of literature and drafted and revised the manuscript	designed the study, contributed significantly to the review of literature and drafted and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
4486418	26130226	KV	2	contributed in reviewing the literature, constructing the figures and table and editing the manuscript	contributed in reviewing the literature, constructing the figures and table and editing the manuscript	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Visualization|Writing - Review & Editing	YES
4486418	26130226	TL	2	critically reviewed the manuscript and contributed by releasing data from his beijing cohort used in this review	critically reviewed the manuscript and contributed by releasing data from his beijing cohort used in this review	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Review & Editing	YES
4486418	26130226	VM	2	designed the study, contributed significantly to the review of literature and drafted and revised the manuscript	designed the study, contributed significantly to the review of literature and drafted and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
4486418	26130226	WC	2	contributed in reviewing the literature, constructing the figures and table and editing the manuscript	contributed in reviewing the literature, constructing the figures and table and editing the manuscript	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Visualization|Writing - Review & Editing	YES
4486418	26130226	WL	2	designed the study, contributed significantly to the review of literature and drafted and revised the manuscript	designed the study, contributed significantly to the review of literature and drafted and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5219790	28061811	AL	2	implemented the microfluidics platform	implemented the microfluidics platform	Performed the experiments	Investigation	YES
5219790	28061811	BW	2	provided rna sequencing core facility support	provided rna sequencing core facility support	Performed the experiments	Investigation	YES
5219790	28061811	CH	2	provided additional statistical support	provided additional statistical support	Analyzed the data	Formal analysis	YES
5219790	28061811	DW	2	created and provided the cell model	created and provided the cell model	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources	YES
5219790	28061811	EM	2	implemented the microfluidics platform|optimised and ran the experimental work	implemented the microfluidics platform	Performed the experiments	Investigation	YES
5219790	28061811	EM	2	implemented the microfluidics platform|optimised and ran the experimental work	optimised and ran the experimental work	Performed the experiments	Investigation	YES
5219790	28061811	ES	2	provided rna sequencing core facility support	provided rna sequencing core facility support	Performed the experiments	Investigation	YES
5219790	28061811	HL	2	provided rna sequencing core facility support	provided rna sequencing core facility support	Performed the experiments	Investigation	YES
5219790	28061811	JB	2	provided rna sequencing core facility support	provided rna sequencing core facility support	Performed the experiments	Investigation	YES
5219790	28061811	JW	2	implemented the microfluidics platform	implemented the microfluidics platform	Performed the experiments	Investigation	YES
5219790	28061811	MG	2	implemented the microfluidics platform	implemented the microfluidics platform	Performed the experiments	Investigation	YES
5219790	28061811	ML	2	implemented the microfluidics platform	implemented the microfluidics platform	Performed the experiments	Investigation	YES
5219790	28061811	MM	2	conceived and supervised the study|created and provided the cell model	conceived and supervised the study	Conceived and designed the experiments	Conceptualization|Supervision	YES
5219790	28061811	MM	2	conceived and supervised the study|created and provided the cell model	created and provided the cell model	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources	YES
5219790	28061811	QW	2	conceived and supervised the study|provided imaging analysis|provided the experimental design and data modeling|wrote the manuscript	conceived and supervised the study	Conceived and designed the experiments	Conceptualization|Supervision	YES
5219790	28061811	QW	2	conceived and supervised the study|provided imaging analysis|provided the experimental design and data modeling|wrote the manuscript	provided imaging analysis	Analyzed the data	Visualization	YES
5219790	28061811	QW	2	conceived and supervised the study|provided imaging analysis|provided the experimental design and data modeling|wrote the manuscript	provided the experimental design and data modeling	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Methodology|Resources	YES
5219790	28061811	QW	2	conceived and supervised the study|provided imaging analysis|provided the experimental design and data modeling|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5219790	28061811	RB	2	conceived and supervised the study|wrote the manuscript	conceived and supervised the study	Conceived and designed the experiments	Conceptualization|Supervision	YES
5219790	28061811	RB	2	conceived and supervised the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5219790	28061811	RN	2	provided imaging analysis	provided imaging analysis	Analyzed the data	Visualization	YES
5219790	28061811	SF	2	contributed to the clustering analysis	contributed to the clustering analysis	Analyzed the data	Formal analysis	YES
5219790	28061811	SP	2	provided imaging analysis	provided imaging analysis	Analyzed the data	Visualization	YES
5219790	28061811	WJ	2	provided critical reading and guidance for the manuscript	provided critical reading and guidance for the manuscript	-	Supervision	YES
4818923	27042193	AL	2	were clinicians who included patients in the trial and all participated to the elaboration of the manuscript	were clinicians who included patients in the trial and all participated to the elaboration of the manuscript	-	-	NO
4818923	27042193	All	2	the patients who took part in the study	the patients who took part in the study	-	-	NO
4818923	27042193	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4818923	27042193	CA	2	were clinicians who included patients in the trial and all participated to the elaboration of the manuscript	were clinicians who included patients in the trial and all participated to the elaboration of the manuscript	-	-	NO
4818923	27042193	IC	2	were responsible for the data management of the trial and all statistical analysis, and also participated to the writing of the manuscript	were responsible for the data management of the trial and all statistical analysis, and also participated to the writing of the manuscript	Analyzed the data|Wrote the paper	Data curation|Formal analysis|Project administration|Writing - Original Draft	YES
4818923	27042193	JB	2	were responsible for the data management of the trial and all statistical analysis, and also participated to the writing of the manuscript	were responsible for the data management of the trial and all statistical analysis, and also participated to the writing of the manuscript	Analyzed the data|Wrote the paper	Data curation|Formal analysis|Project administration|Writing - Original Draft	YES
4818923	27042193	JMM	2	was the co-coordinating pi|equally contributed to the writing of the manuscript	was the co-coordinating pi	-	Project administration	YES
4818923	27042193	JMM	2	was the co-coordinating pi|equally contributed to the writing of the manuscript	equally contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
4818923	27042193	JPA	2	were responsible for the data management of the trial and all statistical analysis, and also participated to the writing of the manuscript	were responsible for the data management of the trial and all statistical analysis, and also participated to the writing of the manuscript	Analyzed the data|Wrote the paper	Data curation|Formal analysis|Project administration|Writing - Original Draft	YES
4818923	27042193	JVV	2	were clinicians who included patients in the trial and all participated to the elaboration of the manuscript	were clinicians who included patients in the trial and all participated to the elaboration of the manuscript	-	-	NO
4818923	27042193	NDC	2	was the coordinating pi of the trial|equally contributed to the writing of the manuscript	was the coordinating pi of the trial	-	Project administration	YES
4818923	27042193	NDC	2	was the coordinating pi of the trial|equally contributed to the writing of the manuscript	equally contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
4720712	26904193	AJF	7	drafting, critical appraisal, approval of final version. NS- concept, critical appraisal, approval of final version	drafting, critical appraisal, approval of final version. NS- concept, critical appraisal, approval of final version	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4720712	26904193	RAA	7	concept, drafting, approval of final version	concept, drafting, approval of final version	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5419350	28970384	Helle Wallach-Kildemoes	2	revised and approved of the final manuscript	revised and approved of the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5419350	28970384	Lotte Stig Norgaard	2	revised and approved of the final manuscript	revised and approved of the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5419350	28970384	Lourdes Cantarero-Arevalo	2	revised and approved of the final manuscript	revised and approved of the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5419350	28970384	Sofia Kalvemark Sporrong	2	wrote the outline of the manuscript|adopted the text pieces into a final manuscript	wrote the outline of the manuscript	Wrote the paper	Writing - Original Draft	YES
5419350	28970384	Sofia Kalvemark Sporrong	2	wrote the outline of the manuscript|adopted the text pieces into a final manuscript	adopted the text pieces into a final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5419350	28970384	Susanne Kaae	2	conceived the original idea of the paper|revised and approved of the final manuscript	conceived the original idea of the paper	Conceived and designed the experiments	Conceptualization	YES
5419350	28970384	Susanne Kaae	2	conceived the original idea of the paper|revised and approved of the final manuscript	revised and approved of the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4720713	26904194	Rasika Hendahewa	7	Concept of manuscript, literature review and editing	Concept of manuscript, literature review and editing	Conceived and designed the experiments|Wrote the paper	Conceptualization|Formal analysis|Writing - Review & Editing	YES
4720713	26904194	Zainab Naseem	7	primary author of the case report, literature review and writing of manuscript. Gamini.Premaratne - literature review and editing	primary author of the case report, literature review and writing of manuscript. Gamini.Premaratne - literature review and editing	Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5509943	28769942	BA	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5509943	28769942	EGB	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4404144	25893242	AG	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4404144	25893242	EAM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404144	25893242	EAM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404144	25893242	EAM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404144	25893242	HK	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4404144	25893242	HK	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4404144	25893242	JSL	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404144	25893242	JSL	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404144	25893242	LAK	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404144	25893242	LAK	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404144	25893242	M. Kanazawa	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4404144	25893242	M. Kanazawa	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4404144	25893242	M. Kano	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4404144	25893242	M. Kano	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4404144	25893242	MA	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4404144	25893242	MA	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404144	25893242	SF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404144	25893242	SF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404144	25893242	SF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404144	25893242	SF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404144	25893242	SF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404144	25893242	TH	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4404144	25893242	TH	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4404144	25893242	TM	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4404144	25893242	TM	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5440599	28373098	A.T.	2	performed sample processing and analysis	performed sample processing and analysis	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5440599	28373098	B.S.	2	performed sample processing and analysis	performed sample processing and analysis	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5440599	28373098	D.G.H.	2	designed and produced of nasosorption and bronchosorption devices	designed and produced of nasosorption and bronchosorption devices	Conceived and designed the experiments	-	YES
5440599	28373098	D.J.J.	2	conceptualized the study design and directed the project|carried out the clinical aspects of the study|performed the bronchoscopies|analysed, reviewed and interpreted data	conceptualized the study design and directed the project	Conceived and designed the experiments	Conceptualization|Methodology|Supervision	YES
5440599	28373098	D.J.J.	2	conceptualized the study design and directed the project|carried out the clinical aspects of the study|performed the bronchoscopies|analysed, reviewed and interpreted data	carried out the clinical aspects of the study	Performed the experiments	Investigation	YES
5440599	28373098	D.J.J.	2	conceptualized the study design and directed the project|carried out the clinical aspects of the study|performed the bronchoscopies|analysed, reviewed and interpreted data	performed the bronchoscopies	Performed the experiments	Investigation	YES
5440599	28373098	D.J.J.	2	conceptualized the study design and directed the project|carried out the clinical aspects of the study|performed the bronchoscopies|analysed, reviewed and interpreted data	analysed, reviewed and interpreted data	Analyzed the data	Formal analysis	YES
5440599	28373098	E.B.	2	performed sample processing and analysis	performed sample processing and analysis	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5440599	28373098	J.A.	2	performed sample processing and analysis	performed sample processing and analysis	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5440599	28373098	J.D.	2	carried out volunteer screenings and assisted with bronchsoscopies	carried out volunteer screenings and assisted with bronchsoscopies	Performed the experiments	Investigation	YES
5440599	28373098	J.K.	2	analysed, reviewed and interpreted data	analysed, reviewed and interpreted data	Analyzed the data	Formal analysis	YES
5440599	28373098	J.W.	2	performed sample processing and analysis	performed sample processing and analysis	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5440599	28373098	J.d.-R.	2	carried out volunteer screenings and assisted with bronchsoscopies	carried out volunteer screenings and assisted with bronchsoscopies	Performed the experiments	Investigation	YES
5440599	28373098	L.G.	2	performed sample processing and analysis	performed sample processing and analysis	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5440599	28373098	L.S.	2	performed sample processing and analysis	performed sample processing and analysis	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5440599	28373098	M.-B.T.-T.	2	carried out volunteer screenings and assisted with bronchsoscopies	carried out volunteer screenings and assisted with bronchsoscopies	Performed the experiments	Investigation	YES
5440599	28373098	M.J.E.	2	performed sample processing and analysis	performed sample processing and analysis	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5440599	28373098	M.S.	2	analysed, reviewed and interpreted data	analysed, reviewed and interpreted data	Analyzed the data	Formal analysis	YES
5440599	28373098	O.M.K.	2	performed the bronchoscopies	performed the bronchoscopies	Performed the experiments	Investigation	YES
5440599	28373098	P.K.	2	analysed, reviewed and interpreted data	analysed, reviewed and interpreted data	Analyzed the data	Formal analysis	YES
5440599	28373098	P.M.	2	conceptualized the study design and directed the project	conceptualized the study design and directed the project	Conceived and designed the experiments	Conceptualization|Methodology|Supervision	YES
5440599	28373098	R.P.W.	2	performed sample processing and analysis	performed sample processing and analysis	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5440599	28373098	S.L.J.	2	conceptualized the study design and directed the project	conceptualized the study design and directed the project	Conceived and designed the experiments	Conceptualization|Methodology|Supervision	YES
5440599	28373098	T.L.H.	2	designed and produced of nasosorption and bronchosorption devices	designed and produced of nasosorption and bronchosorption devices	Conceived and designed the experiments	-	YES
5440599	28373098	T.M.H.	2	designed and produced of nasosorption and bronchosorption devices	designed and produced of nasosorption and bronchosorption devices	Conceived and designed the experiments	-	YES
5440599	28373098	T.T.	2	analysed, reviewed and interpreted data|prepared the manuscript with input from all authors	analysed, reviewed and interpreted data	Analyzed the data	Formal analysis	YES
5440599	28373098	T.T.	2	analysed, reviewed and interpreted data|prepared the manuscript with input from all authors	prepared the manuscript with input from all authors	Wrote the paper	Writing - Original Draft	YES
5440599	28373098	T.T.H.	2	conceptualized the study design and directed the project|designed and produced of nasosorption and bronchosorption devices|analysed, reviewed and interpreted data|prepared the manuscript with input from all authors	conceptualized the study design and directed the project	Conceived and designed the experiments	Conceptualization|Methodology|Supervision	YES
5440599	28373098	T.T.H.	2	conceptualized the study design and directed the project|designed and produced of nasosorption and bronchosorption devices|analysed, reviewed and interpreted data|prepared the manuscript with input from all authors	designed and produced of nasosorption and bronchosorption devices	Conceived and designed the experiments	-	YES
5440599	28373098	T.T.H.	2	conceptualized the study design and directed the project|designed and produced of nasosorption and bronchosorption devices|analysed, reviewed and interpreted data|prepared the manuscript with input from all authors	analysed, reviewed and interpreted data	Analyzed the data	Formal analysis	YES
5440599	28373098	T.T.H.	2	conceptualized the study design and directed the project|designed and produced of nasosorption and bronchosorption devices|analysed, reviewed and interpreted data|prepared the manuscript with input from all authors	prepared the manuscript with input from all authors	Wrote the paper	Writing - Original Draft	YES
5219802	28061859	GJB	2	made contributions to conception and design, interpretation of data, and article drafting	made contributions to conception and design, interpretation of data, and article drafting	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Resources|Writing - Original Draft	YES
5219802	28061859	HVSR	2	performed the data collection, the computational/statistcs analysis, interpretation of the data, and contributions to the drafting of the article	performed the data collection, the computational/statistcs analysis, interpretation of the data, and contributions to the drafting of the article	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5219802	28061859	LHR	2	participated in drafting/writing the article or revising it critically for important intellectual content|revised and approved the final version to be submitted	participated in drafting/writing the article or revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5219802	28061859	LHR	2	participated in drafting/writing the article or revising it critically for important intellectual content|revised and approved the final version to be submitted	revised and approved the final version to be submitted	Wrote the paper	Writing - Review & Editing	YES
5219802	28061859	LOO	2	participated in drafting/writing the article or revising it critically for important intellectual content|revised and approved the final version to be submitted	participated in drafting/writing the article or revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5219802	28061859	LOO	2	participated in drafting/writing the article or revising it critically for important intellectual content|revised and approved the final version to be submitted	revised and approved the final version to be submitted	Wrote the paper	Writing - Review & Editing	YES
4720715	26904196	P Fraglidis	7	critically revised and approved the final draft of the manuscript	critically revised and approved the final draft of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4720715	26904196	P Fragulidis	7	data collection. D. Voros, A. Vezakis, A. Polydorou, G|study design. E. Kontis, A. Vezakis, E. Pantiora, G|wrote the paper. E. Kontis, A. Vezakis, E. Pantiora, S. Stasinopoulou, A. Polydorou, D. Voros, G	data collection. D. Voros, A. Vezakis, A. Polydorou, G	Performed the experiments	Investigation	YES
4720715	26904196	P Fragulidis	7	data collection. D. Voros, A. Vezakis, A. Polydorou, G|study design. E. Kontis, A. Vezakis, E. Pantiora, G|wrote the paper. E. Kontis, A. Vezakis, E. Pantiora, S. Stasinopoulou, A. Polydorou, D. Voros, G	study design. E. Kontis, A. Vezakis, E. Pantiora, G	Conceived and designed the experiments	Methodology	YES
4720715	26904196	P Fragulidis	7	data collection. D. Voros, A. Vezakis, A. Polydorou, G|study design. E. Kontis, A. Vezakis, E. Pantiora, G|wrote the paper. E. Kontis, A. Vezakis, E. Pantiora, S. Stasinopoulou, A. Polydorou, D. Voros, G	wrote the paper. E. Kontis, A. Vezakis, E. Pantiora, S. Stasinopoulou, A. Polydorou, D. Voros, G	Wrote the paper	Writing - Original Draft	YES
4826516	27064450	AC	PLoS5	Performed the study	Performed the study	Performed the experiments	Investigation	YES
4826516	27064450	CT	PLoS5	Performed the study	Performed the study	Performed the experiments	Investigation	YES
4826516	27064450	DF	PLoS5	Performed the study	Performed the study	Performed the experiments	Investigation	YES
4826516	27064450	ES	PLoS5	Performed the study	Performed the study	Performed the experiments	Investigation	YES
4826516	27064450	KP	PLoS5	Technical support to research	Technical support to research	Performed the experiments	Investigation	YES
4826516	27064450	LF	PLoS5	Designed the software used in analysis	Designed the software used in analysis	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
4826516	27064450	MC	PLoS5	Performed the study	Performed the study	Performed the experiments	Investigation	YES
4826516	27064450	MDG	PLoS5	Designed the software used in analysis	Designed the software used in analysis	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
4826516	27064450	MM	PLoS5	Designed the software used in analysis	Designed the software used in analysis	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
4826516	27064450	RB	PLoS5	Conceived and designed the study|Performed the study|Analyzed the data|Wrote the paper	Conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4826516	27064450	RB	PLoS5	Conceived and designed the study|Performed the study|Analyzed the data|Wrote the paper	Performed the study	Performed the experiments	Investigation	YES
4826516	27064450	RB	PLoS5	Conceived and designed the study|Performed the study|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4826516	27064450	RB	PLoS5	Conceived and designed the study|Performed the study|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4826516	27064450	RM	PLoS5	Conceived and designed the study	Conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4826516	27064450	SL	PLoS5	Designed the software used in analysis	Designed the software used in analysis	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
4826516	27064450	SP	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4826516	27064450	SV	PLoS5	Conceived and designed the study|Wrote the paper	Conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4826516	27064450	SV	PLoS5	Conceived and designed the study|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4826516	27064450	VF	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5509946	28769938	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5509946	28769938	CL	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5509946	28769938	HJ	PLoS52	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5509946	28769938	LL	PLoS52	conceived and designed the research	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5509946	28769938	LX	PLoS52	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5509946	28769938	WZ	PLoS52	contributed powerful analytical tools	contributed powerful analytical tools	Contributed reagents/materials/analysis tools	Resources	YES
5509946	28769938	XL	PLoS52	contributed powerful analytical tools	contributed powerful analytical tools	Contributed reagents/materials/analysis tools	Resources	YES
5509946	28769938	XS	PLoS52	conceived and designed the research|performed the experiments|analyzed data|wrote the manuscript	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5509946	28769938	XS	PLoS52	conceived and designed the research|performed the experiments|analyzed data|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5509946	28769938	XS	PLoS52	conceived and designed the research|performed the experiments|analyzed data|wrote the manuscript	analyzed data	Analyzed the data	Formal analysis	YES
5509946	28769938	XS	PLoS52	conceived and designed the research|performed the experiments|analyzed data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5509946	28769938	YW	PLoS52	conceived and designed the research|performed the experiments|analyzed data	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5509946	28769938	YW	PLoS52	conceived and designed the research|performed the experiments|analyzed data	performed the experiments	Performed the experiments	Investigation	YES
5509946	28769938	YW	PLoS52	conceived and designed the research|performed the experiments|analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
4404153	25894343	AI	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404153	25894343	AI	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404153	25894343	AI	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404153	25894343	AI	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404153	25894343	CYC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404153	25894343	CYC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404153	25894343	CYC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404153	25894343	CYC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404153	25894343	ES	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404153	25894343	ES	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404153	25894343	ES	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404153	25894343	OS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404153	25894343	OS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404153	25894343	OS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404153	25894343	OS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404153	25894343	OS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404153	25894343	SN	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4404153	25894343	SS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404153	25894343	SS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404153	25894343	SS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5419352	28970377	EH	2	participated in study design and implementation and provided critical review and edits to the manuscript	participated in study design and implementation and provided critical review and edits to the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
5419352	28970377	JEM	2	provided oversight for the design and implementation of the study, provided support for data analysis and interpretation, and contributed to writing the manuscript	provided oversight for the design and implementation of the study, provided support for data analysis and interpretation, and contributed to writing the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Supervision|Writing - Original Draft	YES
5419352	28970377	JM	2	participated in study design and implementation and provided critical review and edits to the manuscript	participated in study design and implementation and provided critical review and edits to the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
5419352	28970377	SS	2	took the lead on designing and implementing the study, conducting data analyses, and writing the manuscript	took the lead on designing and implementing the study, conducting data analyses, and writing the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5419352	28970377	UNC	2	medical center and engaged in critical review and edits to the manuscript	medical center and engaged in critical review and edits to the manuscript	Wrote the paper	Writing - Review & Editing	YES
5440600	28434946	All authors	2	contributed through critical reading and feedback that refined the manuscript to completion	contributed through critical reading and feedback that refined the manuscript to completion	-	-	NO
5440600	28434946	FWKT	2	supervised design and data analysis|provided critical interpretation of study results that helped rim produce a comprehensive report	supervised design and data analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Supervision	YES
5440600	28434946	FWKT	2	supervised design and data analysis|provided critical interpretation of study results that helped rim produce a comprehensive report	provided critical interpretation of study results that helped rim produce a comprehensive report	Analyzed the data	Formal analysis	YES
5440600	28434946	JJM	2	provided critical interpretation of study results that helped rim produce a comprehensive report	provided critical interpretation of study results that helped rim produce a comprehensive report	Analyzed the data	Formal analysis	YES
5440600	28434946	JTN	2	supervised design and data analysis|provided critical interpretation of study results that helped rim produce a comprehensive report	supervised design and data analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Supervision	YES
5440600	28434946	JTN	2	supervised design and data analysis|provided critical interpretation of study results that helped rim produce a comprehensive report	provided critical interpretation of study results that helped rim produce a comprehensive report	Analyzed the data	Formal analysis	YES
5440600	28434946	JWRB	2	performed the experiments and collected the data	performed the experiments and collected the data	Performed the experiments	Investigation	YES
5440600	28434946	MAB	2	provided critical interpretation of study results that helped rim produce a comprehensive report	provided critical interpretation of study results that helped rim produce a comprehensive report	Analyzed the data	Formal analysis	YES
5440600	28434946	RIM	2	analyzed the data, produced the figures, and wrote the manuscript	analyzed the data, produced the figures, and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Visualization|Writing - Original Draft	YES
5440600	28434946	RJU	2	supervised design and data analysis|provided critical interpretation of study results that helped rim produce a comprehensive report	supervised design and data analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Supervision	YES
5440600	28434946	RJU	2	supervised design and data analysis|provided critical interpretation of study results that helped rim produce a comprehensive report	provided critical interpretation of study results that helped rim produce a comprehensive report	Analyzed the data	Formal analysis	YES
4495612	26154734	AZ	2	authors have reviewed and approved the final version of the manuscript	authors have reviewed and approved the final version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4495612	26154734	All	2	authors have reviewed and approved the final version of the manuscript	authors have reviewed and approved the final version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4495612	26154734	EJA	2	conceptualized the study question|authors have reviewed and approved the final version of the manuscript	conceptualized the study question	Conceived and designed the experiments	Conceptualization	YES
4495612	26154734	EJA	2	conceptualized the study question|authors have reviewed and approved the final version of the manuscript	authors have reviewed and approved the final version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4495612	26154734	GP	2	authors have reviewed and approved the final version of the manuscript	authors have reviewed and approved the final version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4495612	26154734	JAM	2	authors have reviewed and approved the final version of the manuscript	authors have reviewed and approved the final version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4495612	26154734	LGB	2	authors have reviewed and approved the final version of the manuscript	authors have reviewed and approved the final version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4495612	26154734	LM	2	conceptualized the study question	conceptualized the study question	Conceived and designed the experiments	Conceptualization	YES
4495612	26154734	NYH	2	authors have reviewed and approved the final version of the manuscript	authors have reviewed and approved the final version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4495612	26154734	TP	2	authors have reviewed and approved the final version of the manuscript	authors have reviewed and approved the final version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5219805	28061804	CC	PLoS52	designed the research|supervised the research|wrote the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
5219805	28061804	CC	PLoS52	designed the research|supervised the research|wrote the manuscript	supervised the research	-	Supervision	YES
5219805	28061804	CC	PLoS52	designed the research|supervised the research|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5219805	28061804	CL	PLoS52	designed the research|supervised the research|wrote the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
5219805	28061804	CL	PLoS52	designed the research|supervised the research|wrote the manuscript	supervised the research	-	Supervision	YES
5219805	28061804	CL	PLoS52	designed the research|supervised the research|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5219805	28061804	MS	PLoS52	performed experiments|supervised the research|analyzed the data|wrote the manuscript	performed experiments	Performed the experiments	Investigation	YES
5219805	28061804	MS	PLoS52	performed experiments|supervised the research|analyzed the data|wrote the manuscript	supervised the research	-	Supervision	YES
5219805	28061804	MS	PLoS52	performed experiments|supervised the research|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5219805	28061804	MS	PLoS52	performed experiments|supervised the research|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5219805	28061804	PG	PLoS52	performed experiments|analyzed the data	performed experiments	Performed the experiments	Investigation	YES
5219805	28061804	PG	PLoS52	performed experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5219805	28061804	PVG	PLoS52	designed the research|performed experiments|analyzed the data|wrote the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
5219805	28061804	PVG	PLoS52	designed the research|performed experiments|analyzed the data|wrote the manuscript	performed experiments	Performed the experiments	Investigation	YES
5219805	28061804	PVG	PLoS52	designed the research|performed experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5219805	28061804	PVG	PLoS52	designed the research|performed experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5219805	28061804	SBO	PLoS52	performed experiments|analyzed the data	performed experiments	Performed the experiments	Investigation	YES
5219805	28061804	SBO	PLoS52	performed experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
4720716	26904191	Allan Beharry	2	researched paper, corrected data	researched paper, corrected data	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4720716	26904191	Justin Mooteeram	2	researched paper, corrected data	researched paper, corrected data	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4720716	26904191	Shaheeba Barrow	2	was the pathologist and assisted in editing the paper	was the pathologist and assisted in editing the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5419353	28970387	All authors	2	interpreted the data and drafted the manuscript	interpreted the data and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5419353	28970387	Joshua D. Brown	2	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5419353	28970387	Nathan J. Pauly	2	performed the data analysis	performed the data analysis	Analyzed the data	Formal analysis	YES
4720717	26904190	Gerrad Gillan	7	Critical revision and final approval	Critical revision and final approval	Wrote the paper	Writing - Review & Editing	YES
4720717	26904190	Kim Piper	7	Final approval	Final approval	-	-	NO
4720717	26904190	Sandra Girgis	7	Concept of case report, review of literature, critical revision and final approval	Concept of case report, review of literature, critical revision and final approval	Conceived and designed the experiments|Wrote the paper	Conceptualization|Formal analysis|Writing - Review & Editing	YES
4404164	25893662	CC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404164	25893662	CC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404164	25893662	CC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404164	25893662	CC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404164	25893662	CJC	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404164	25893662	CJC	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404164	25893662	CJC	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404164	25893662	CJC	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404164	25893662	JET	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404164	25893662	JET	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404164	25893662	JET	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404164	25893662	JET	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404164	25893662	MJD	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404164	25893662	MJD	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404164	25893662	MJD	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404164	25893662	MJD	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404164	25893662	PSH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404164	25893662	PSH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404164	25893662	PSH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404164	25893662	PSH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4499059	26163505	BN	2	contributed to study design, interpretation of the results, reviewed and gave comments to all draft versions of the paper	contributed to study design, interpretation of the results, reviewed and gave comments to all draft versions of the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
4499059	26163505	CK	2	reviewed and gave comments to all draft versions of the paper	reviewed and gave comments to all draft versions of the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4499059	26163505	CRC	2	reviewed and gave comments to all draft versions of the paper	reviewed and gave comments to all draft versions of the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4499059	26163505	EB	2	contributed to study design, interpretation of the results, reviewed and gave comments to all draft versions of the paper	contributed to study design, interpretation of the results, reviewed and gave comments to all draft versions of the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
4499059	26163505	PO	2	reviewed and gave comments to all draft versions of the paper	reviewed and gave comments to all draft versions of the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4499059	26163505	RS	2	contributed to study design, interpretation of the results, reviewed and gave comments to all draft versions of the paper	contributed to study design, interpretation of the results, reviewed and gave comments to all draft versions of the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
4828806	27073405	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4828806	27073405	CT	2	conceived and wrote the manuscript	conceived and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4828806	27073405	DCD	2	critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4828806	27073405	GM	2	conceived and wrote the manuscript|critically revised the manuscript	conceived and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4828806	27073405	GM	2	conceived and wrote the manuscript|critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5510571	28769950	FG	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5510571	28769950	JM	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5510571	28769950	JZ	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5510571	28769950	LC	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5510571	28769950	SW	2	planned and designed the research	planned and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5510571	28769950	SY	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5510571	28769950	XL	2	planned and designed the research|wrote the manuscript	planned and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5510571	28769950	XL	2	planned and designed the research|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5510571	28769950	YG	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5510571	28769950	YL	2	performed experiments|collected data and conducted analysis|wrote the manuscript	performed experiments	Performed the experiments	Investigation	YES
5510571	28769950	YL	2	performed experiments|collected data and conducted analysis|wrote the manuscript	collected data and conducted analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5510571	28769950	YL	2	performed experiments|collected data and conducted analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5440601	28434945	All authors	PLoS52	reviewed and approved the final manuscript	reviewed and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5440601	28434945	B.L.	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5440601	28434945	J.C.	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5440601	28434945	J.W.	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5440601	28434945	J.Z.	PLoS52	contributed to the study concept and design|obtained funding and provided the essential materials|analyzed the data	contributed to the study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5440601	28434945	J.Z.	PLoS52	contributed to the study concept and design|obtained funding and provided the essential materials|analyzed the data	obtained funding and provided the essential materials	Contributed reagents/materials/analysis tools	Funding acquisition|Resources	YES
5440601	28434945	J.Z.	PLoS52	contributed to the study concept and design|obtained funding and provided the essential materials|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5440601	28434945	M.Z.	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5440601	28434945	P.C.	PLoS52	contributed to the study concept and design|obtained funding and provided the essential materials|wrote the manuscript	contributed to the study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5440601	28434945	P.C.	PLoS52	contributed to the study concept and design|obtained funding and provided the essential materials|wrote the manuscript	obtained funding and provided the essential materials	Contributed reagents/materials/analysis tools	Funding acquisition|Resources	YES
5440601	28434945	P.C.	PLoS52	contributed to the study concept and design|obtained funding and provided the essential materials|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5440601	28434945	S.L.	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5440601	28434945	X.F.	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5440601	28434945	X.J.	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5440601	28434945	X.Z.	PLoS52	contributed to the study concept and design|obtained funding and provided the essential materials|wrote the manuscript	contributed to the study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5440601	28434945	X.Z.	PLoS52	contributed to the study concept and design|obtained funding and provided the essential materials|wrote the manuscript	obtained funding and provided the essential materials	Contributed reagents/materials/analysis tools	Funding acquisition|Resources	YES
5440601	28434945	X.Z.	PLoS52	contributed to the study concept and design|obtained funding and provided the essential materials|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5440601	28434945	Y.Z.	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
4720718	26904188	Edgaras Smolskas	2	conducted the study, performed the literature search and wrote the paper	conducted the study, performed the literature search and wrote the paper	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4720718	26904188	Narimantas Evaldas Samalavicius	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
4720718	26904188	Raimundas Lunevicius	2	performed literature search, supervised the project and made critical revisions	performed literature search, supervised the project and made critical revisions	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Supervision|Writing - Review & Editing	YES
5220608	28068903	FK	7	Finalized the manuscripts	Finalized the manuscripts	Wrote the paper	Writing - Review & Editing	YES
5220608	28068903	LR	7	Conceived and designed the experiments|Finalized the manuscripts	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5220608	28068903	LR	7	Conceived and designed the experiments|Finalized the manuscripts	Finalized the manuscripts	Wrote the paper	Writing - Review & Editing	YES
5220608	28068903	RKS	7	Finalized the manuscripts	Finalized the manuscripts	Wrote the paper	Writing - Review & Editing	YES
5220608	28068903	SB	7	Finalized the manuscripts	Finalized the manuscripts	Wrote the paper	Writing - Review & Editing	YES
5220608	28068903	SG	7	Finalized the manuscripts	Finalized the manuscripts	Wrote the paper	Writing - Review & Editing	YES
5220608	28068903	SK	7	Analyzed the data|prepare the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
5220608	28068903	SK	7	Analyzed the data|prepare the manuscript	prepare the manuscript	Wrote the paper	Writing - Original Draft	YES
5220608	28068903	ST	7	Biochemical analysis	Biochemical analysis	Performed the experiments	Investigation	YES
5220608	28068903	SU	7	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5220608	28068903	VG	7	Finalized the manuscripts	Finalized the manuscripts	Wrote the paper	Writing - Review & Editing	YES
4720719	26904192	AU	2	were involved in the conception, design and interpretation	were involved in the conception, design and interpretation	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
4720719	26904192	HY	2	collected data, reviewed relevant published reports and provided the images	collected data, reviewed relevant published reports and provided the images	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
4720719	26904192	IK	2	were involved in the conception, design and interpretation|wrote the manuscript|collected data, reviewed relevant published reports and provided the images	were involved in the conception, design and interpretation	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
4720719	26904192	IK	2	were involved in the conception, design and interpretation|wrote the manuscript|collected data, reviewed relevant published reports and provided the images	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4720719	26904192	IK	2	were involved in the conception, design and interpretation|wrote the manuscript|collected data, reviewed relevant published reports and provided the images	collected data, reviewed relevant published reports and provided the images	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
4720719	26904192	MD	2	collected data, reviewed relevant published reports and provided the images	collected data, reviewed relevant published reports and provided the images	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
4720719	26904192	SM	2	were involved in the conception, design and interpretation|wrote the manuscript|collected data, reviewed relevant published reports and provided the images	were involved in the conception, design and interpretation	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
4720719	26904192	SM	2	were involved in the conception, design and interpretation|wrote the manuscript|collected data, reviewed relevant published reports and provided the images	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4720719	26904192	SM	2	were involved in the conception, design and interpretation|wrote the manuscript|collected data, reviewed relevant published reports and provided the images	collected data, reviewed relevant published reports and provided the images	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
4720719	26904192	TD	2	were involved in the conception, design and interpretation|wrote the manuscript	were involved in the conception, design and interpretation	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
4720719	26904192	TD	2	were involved in the conception, design and interpretation|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4466362	26125028	Annette Kraegeloh	2	contributed to the interpretation of data, the preparation of the paper, and approval of the final version	contributed to the interpretation of data, the preparation of the paper, and approval of the final version	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
4466362	26125028	Christian Cavelius	2	performed particle synthesis and characterization	performed particle synthesis and characterization	Performed the experiments	Investigation	YES
4466362	26125028	Henrike Peuschel	2	contributed equally to this work|designed the study|performed the cell experiments	contributed equally to this work	-	-	NO
4466362	26125028	Henrike Peuschel	2	contributed equally to this work|designed the study|performed the cell experiments	designed the study	Conceived and designed the experiments	Methodology	YES
4466362	26125028	Henrike Peuschel	2	contributed equally to this work|designed the study|performed the cell experiments	performed the cell experiments	Performed the experiments	Investigation	YES
4466362	26125028	Thomas Ruckelshausen	2	contributed equally to this work|designed the study	contributed equally to this work	-	-	NO
4466362	26125028	Thomas Ruckelshausen	2	contributed equally to this work|designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
4466362	26125028	all authors	2	contributed to the interpretation of data, the preparation of the paper, and approval of the final version	contributed to the interpretation of data, the preparation of the paper, and approval of the final version	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5419354	28970386	Agnieska Skowron	2	helped with distribution of the survey	helped with distribution of the survey	Performed the experiments	Investigation	YES
5419354	28970386	Annie Marcincal	2	helped with distribution of the survey	helped with distribution of the survey	Performed the experiments	Investigation	YES
5419354	28970386	Antonio Sanchez Pozo	2	developed the questionnaire|helped with distribution of the survey	developed the questionnaire	-	-	NO
5419354	28970386	Antonio Sanchez Pozo	2	developed the questionnaire|helped with distribution of the survey	helped with distribution of the survey	Performed the experiments	Investigation	YES
5419354	28970386	Borut Bozic	2	helped with distribution of the survey	helped with distribution of the survey	Performed the experiments	Investigation	YES
5419354	28970386	Chris van Schravendijk	2	assured the contacts with medine2	assured the contacts with medine2	-	-	NO
5419354	28970386	Constantin Mircioiu	2	played a major role in the statistical analyses of the data	played a major role in the statistical analyses of the data	Analyzed the data	Formal analysis	YES
5419354	28970386	Dimitrios Rekkas	2	developed the questionnaire|helped with distribution of the survey	developed the questionnaire	-	-	NO
5419354	28970386	Dimitrios Rekkas	2	developed the questionnaire|helped with distribution of the survey	helped with distribution of the survey	Performed the experiments	Investigation	YES
5419354	28970386	Jeffrey Atkinson	2	designed, constructed, ran and analyzed the survey and wrote the paper	designed, constructed, ran and analyzed the survey and wrote the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5419354	28970386	Jouni Hirvonen	2	helped with distribution of the survey	helped with distribution of the survey	Performed the experiments	Investigation	YES
5419354	28970386	Kristien De Paepe	2	ran the phar-qa consortium	ran the phar-qa consortium	Performed the experiments	Investigation	YES
4499577	26165322	BES	PLoS52	conceived and designed the study|analyzed the data|wrote the draft manuscript|did the critical appraisal of the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4499577	26165322	BES	PLoS52	conceived and designed the study|analyzed the data|wrote the draft manuscript|did the critical appraisal of the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
4499577	26165322	BES	PLoS52	conceived and designed the study|analyzed the data|wrote the draft manuscript|did the critical appraisal of the manuscript	wrote the draft manuscript	Wrote the paper	Writing - Original Draft	YES
4499577	26165322	BES	PLoS52	conceived and designed the study|analyzed the data|wrote the draft manuscript|did the critical appraisal of the manuscript	did the critical appraisal of the manuscript	-	-	NO
4499577	26165322	BG	PLoS52	conceived and designed the study|did the critical appraisal of the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4499577	26165322	BG	PLoS52	conceived and designed the study|did the critical appraisal of the manuscript	did the critical appraisal of the manuscript	-	-	NO
4499577	26165322	CCM	PLoS52	conceived and designed the study|did the critical appraisal of the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4499577	26165322	CCM	PLoS52	conceived and designed the study|did the critical appraisal of the manuscript	did the critical appraisal of the manuscript	-	-	NO
4499577	26165322	DP	PLoS52	conceived and designed the study|performed data abstraction|did the critical appraisal of the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4499577	26165322	DP	PLoS52	conceived and designed the study|performed data abstraction|did the critical appraisal of the manuscript	performed data abstraction	-	-	NO
4499577	26165322	DP	PLoS52	conceived and designed the study|performed data abstraction|did the critical appraisal of the manuscript	did the critical appraisal of the manuscript	-	-	NO
4499577	26165322	EG	PLoS52	conceived and designed the study|performed data abstraction|did the critical appraisal of the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4499577	26165322	EG	PLoS52	conceived and designed the study|performed data abstraction|did the critical appraisal of the manuscript	performed data abstraction	-	-	NO
4499577	26165322	EG	PLoS52	conceived and designed the study|performed data abstraction|did the critical appraisal of the manuscript	did the critical appraisal of the manuscript	-	-	NO
4499577	26165322	GC	PLoS52	conceived and designed the study|performed data abstraction|analyzed the data|wrote the draft manuscript|did the critical appraisal of the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4499577	26165322	GC	PLoS52	conceived and designed the study|performed data abstraction|analyzed the data|wrote the draft manuscript|did the critical appraisal of the manuscript	performed data abstraction	-	-	NO
4499577	26165322	GC	PLoS52	conceived and designed the study|performed data abstraction|analyzed the data|wrote the draft manuscript|did the critical appraisal of the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
4499577	26165322	GC	PLoS52	conceived and designed the study|performed data abstraction|analyzed the data|wrote the draft manuscript|did the critical appraisal of the manuscript	wrote the draft manuscript	Wrote the paper	Writing - Original Draft	YES
4499577	26165322	GC	PLoS52	conceived and designed the study|performed data abstraction|analyzed the data|wrote the draft manuscript|did the critical appraisal of the manuscript	did the critical appraisal of the manuscript	-	-	NO
4499577	26165322	JRK	PLoS52	conceived and designed the study|analyzed the data|wrote the draft manuscript|did the critical appraisal of the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4499577	26165322	JRK	PLoS52	conceived and designed the study|analyzed the data|wrote the draft manuscript|did the critical appraisal of the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
4499577	26165322	JRK	PLoS52	conceived and designed the study|analyzed the data|wrote the draft manuscript|did the critical appraisal of the manuscript	wrote the draft manuscript	Wrote the paper	Writing - Original Draft	YES
4499577	26165322	JRK	PLoS52	conceived and designed the study|analyzed the data|wrote the draft manuscript|did the critical appraisal of the manuscript	did the critical appraisal of the manuscript	-	-	NO
4499577	26165322	JS	PLoS52	conceived and designed the study|performed data abstraction|did the critical appraisal of the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4499577	26165322	JS	PLoS52	conceived and designed the study|performed data abstraction|did the critical appraisal of the manuscript	performed data abstraction	-	-	NO
4499577	26165322	JS	PLoS52	conceived and designed the study|performed data abstraction|did the critical appraisal of the manuscript	did the critical appraisal of the manuscript	-	-	NO
4499577	26165322	JWP	PLoS52	conceived and designed the study|performed data abstraction|did the critical appraisal of the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4499577	26165322	JWP	PLoS52	conceived and designed the study|performed data abstraction|did the critical appraisal of the manuscript	performed data abstraction	-	-	NO
4499577	26165322	JWP	PLoS52	conceived and designed the study|performed data abstraction|did the critical appraisal of the manuscript	did the critical appraisal of the manuscript	-	-	NO
4499577	26165322	KJ	PLoS52	conceived and designed the study|performed data management|did the critical appraisal of the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4499577	26165322	KJ	PLoS52	conceived and designed the study|performed data management|did the critical appraisal of the manuscript	performed data management	Analyzed the data	Data curation	YES
4499577	26165322	KJ	PLoS52	conceived and designed the study|performed data management|did the critical appraisal of the manuscript	did the critical appraisal of the manuscript	-	-	NO
4499577	26165322	MB	PLoS52	conceived and designed the study|performed data animation|did the critical appraisal of the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4499577	26165322	MB	PLoS52	conceived and designed the study|performed data animation|did the critical appraisal of the manuscript	performed data animation	-	-	NO
4499577	26165322	MB	PLoS52	conceived and designed the study|performed data animation|did the critical appraisal of the manuscript	did the critical appraisal of the manuscript	-	-	NO
4499577	26165322	MJG	PLoS52	conceived and designed the study|analyzed the data|wrote the draft manuscript|did the critical appraisal of the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4499577	26165322	MJG	PLoS52	conceived and designed the study|analyzed the data|wrote the draft manuscript|did the critical appraisal of the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
4499577	26165322	MJG	PLoS52	conceived and designed the study|analyzed the data|wrote the draft manuscript|did the critical appraisal of the manuscript	wrote the draft manuscript	Wrote the paper	Writing - Original Draft	YES
4499577	26165322	MJG	PLoS52	conceived and designed the study|analyzed the data|wrote the draft manuscript|did the critical appraisal of the manuscript	did the critical appraisal of the manuscript	-	-	NO
4499577	26165322	MW	PLoS52	conceived and designed the study|performed data abstraction|did the critical appraisal of the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4499577	26165322	MW	PLoS52	conceived and designed the study|performed data abstraction|did the critical appraisal of the manuscript	performed data abstraction	-	-	NO
4499577	26165322	MW	PLoS52	conceived and designed the study|performed data abstraction|did the critical appraisal of the manuscript	did the critical appraisal of the manuscript	-	-	NO
4499577	26165322	PC	PLoS52	conceived and designed the study|performed data abstraction|did the critical appraisal of the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4499577	26165322	PC	PLoS52	conceived and designed the study|performed data abstraction|did the critical appraisal of the manuscript	performed data abstraction	-	-	NO
4499577	26165322	PC	PLoS52	conceived and designed the study|performed data abstraction|did the critical appraisal of the manuscript	did the critical appraisal of the manuscript	-	-	NO
4499577	26165322	VF	PLoS52	conceived and designed the study|performed data abstraction|analyzed the data|wrote the draft manuscript|did the critical appraisal of the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4499577	26165322	VF	PLoS52	conceived and designed the study|performed data abstraction|analyzed the data|wrote the draft manuscript|did the critical appraisal of the manuscript	performed data abstraction	-	-	NO
4499577	26165322	VF	PLoS52	conceived and designed the study|performed data abstraction|analyzed the data|wrote the draft manuscript|did the critical appraisal of the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
4499577	26165322	VF	PLoS52	conceived and designed the study|performed data abstraction|analyzed the data|wrote the draft manuscript|did the critical appraisal of the manuscript	wrote the draft manuscript	Wrote the paper	Writing - Original Draft	YES
4499577	26165322	VF	PLoS52	conceived and designed the study|performed data abstraction|analyzed the data|wrote the draft manuscript|did the critical appraisal of the manuscript	did the critical appraisal of the manuscript	-	-	NO
4831200	27081393	AW	2	conceived the design of the study	conceived the design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4831200	27081393	All authors	2	contributed to the writing of the final manuscript|read and approved the final manuscript	contributed to the writing of the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4831200	27081393	All authors	2	contributed to the writing of the final manuscript|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4831200	27081393	BMP	2	drafted this manuscript and performed the analysis for this report	drafted this manuscript and performed the analysis for this report	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4831200	27081393	Imperial College London	2	for infrastructure support	for infrastructure support	-	-	NO
4831200	27081393	ST	2	conceived the design of the study	conceived the design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404247	25894196	JC	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404247	25894196	JC	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404247	25894196	MKD	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404247	25894196	MKD	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404247	25894196	QH	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404247	25894196	QH	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404247	25894196	SZ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404247	25894196	SZ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404247	25894196	SZ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404247	25894196	W. Li	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404247	25894196	W. Li	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404247	25894196	W. Liu	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404247	25894196	W. Liu	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404247	25894196	W. Liu	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5223305	28068922	All authors	2	contributed to manuscript writing	contributed to manuscript writing	Wrote the paper	Writing - Original Draft	YES
5223305	28068922	GBM	2	contributed to animal study	contributed to animal study	Performed the experiments	Investigation	YES
5223305	28068922	GL	2	performed the molecular analysis, data analysis and draft writing	performed the molecular analysis, data analysis and draft writing	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5223305	28068922	LLG	2	contributed to interpretation of the molecular data	contributed to interpretation of the molecular data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5223305	28068922	YG	2	performed the molecular analysis, data analysis and draft writing|contributed to animal study	performed the molecular analysis, data analysis and draft writing	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5223305	28068922	YG	2	performed the molecular analysis, data analysis and draft writing|contributed to animal study	contributed to animal study	Performed the experiments	Investigation	YES
5440605	28473239	A.T.	2	performed the statistical analysis and prepared the tables/figures	performed the statistical analysis and prepared the tables/figures	Analyzed the data	Formal analysis|Visualization	YES
5440605	28473239	All authors	2	helped draft the manuscript, participated in manuscript editing and read/approved the final manuscript	helped draft the manuscript, participated in manuscript editing and read/approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5440605	28473239	B.S.	2	participated in the analysis	participated in the analysis	-	-	NO
5440605	28473239	C.C.	2	participated in the study design and/or collected the samples/physiological measurements|conceived of the study, its design, and its coordination	participated in the study design and/or collected the samples/physiological measurements	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5440605	28473239	C.C.	2	participated in the study design and/or collected the samples/physiological measurements|conceived of the study, its design, and its coordination	conceived of the study, its design, and its coordination	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
5440605	28473239	C.E.C.	2	participated in the study design and/or collected the samples/physiological measurements	participated in the study design and/or collected the samples/physiological measurements	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5440605	28473239	C.P.C.	2	participated in the study design and/or collected the samples/physiological measurements	participated in the study design and/or collected the samples/physiological measurements	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5440605	28473239	C.Y.C.	2	carried out the molecular epigenetic studies	carried out the molecular epigenetic studies	Performed the experiments	Investigation	YES
5440605	28473239	E.C.	2	carried out the molecular epigenetic studies	carried out the molecular epigenetic studies	Performed the experiments	Investigation	YES
5440605	28473239	E.G.	2	carried out the molecular epigenetic studies	carried out the molecular epigenetic studies	Performed the experiments	Investigation	YES
5440605	28473239	G.B.	2	participated in the study design and/or collected the samples/physiological measurements	participated in the study design and/or collected the samples/physiological measurements	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5440605	28473239	H.I.	2	participated in the study design and/or collected the samples/physiological measurements	participated in the study design and/or collected the samples/physiological measurements	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5440605	28473239	J.H.	2	performed the statistical analysis and prepared the tables/figures|participated in the study design and/or collected the samples/physiological measurements	performed the statistical analysis and prepared the tables/figures	Analyzed the data	Formal analysis|Visualization	YES
5440605	28473239	J.H.	2	performed the statistical analysis and prepared the tables/figures|participated in the study design and/or collected the samples/physiological measurements	participated in the study design and/or collected the samples/physiological measurements	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5440605	28473239	K.L.	2	drafted the manuscript|participated in the study design and/or collected the samples/physiological measurements|conceived of the study, its design, and its coordination	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5440605	28473239	K.L.	2	drafted the manuscript|participated in the study design and/or collected the samples/physiological measurements|conceived of the study, its design, and its coordination	participated in the study design and/or collected the samples/physiological measurements	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5440605	28473239	K.L.	2	drafted the manuscript|participated in the study design and/or collected the samples/physiological measurements|conceived of the study, its design, and its coordination	conceived of the study, its design, and its coordination	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
5440605	28473239	K.M.G.	2	drafted the manuscript|participated in the study design and/or collected the samples/physiological measurements|conceived of the study, its design, and its coordination	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5440605	28473239	K.M.G.	2	drafted the manuscript|participated in the study design and/or collected the samples/physiological measurements|conceived of the study, its design, and its coordination	participated in the study design and/or collected the samples/physiological measurements	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5440605	28473239	K.M.G.	2	drafted the manuscript|participated in the study design and/or collected the samples/physiological measurements|conceived of the study, its design, and its coordination	conceived of the study, its design, and its coordination	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
5440605	28473239	L.B.	2	performed the statistical analysis and prepared the tables/figures	performed the statistical analysis and prepared the tables/figures	Analyzed the data	Formal analysis|Visualization	YES
5440605	28473239	M.H.	2	conceived of the study, its design, and its coordination	conceived of the study, its design, and its coordination	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
5440605	28473239	N.H.	2	participated in the study design and/or collected the samples/physiological measurements	participated in the study design and/or collected the samples/physiological measurements	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5440605	28473239	N.K.	2	participated in the study design and/or collected the samples/physiological measurements	participated in the study design and/or collected the samples/physiological measurements	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5440605	28473239	P.C.	2	carried out the molecular epigenetic studies	carried out the molecular epigenetic studies	Performed the experiments	Investigation	YES
5440605	28473239	P.C.C.	2	participated in the study design and/or collected the samples/physiological measurements	participated in the study design and/or collected the samples/physiological measurements	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5440605	28473239	P.D.G.	2	conceived of the study, its design, and its coordination	conceived of the study, its design, and its coordination	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
5440605	28473239	P.M.	2	performed the statistical analysis and prepared the tables/figures	performed the statistical analysis and prepared the tables/figures	Analyzed the data	Formal analysis|Visualization	YES
5440605	28473239	P.T.	2	performed the statistical analysis and prepared the tables/figures	performed the statistical analysis and prepared the tables/figures	Analyzed the data	Formal analysis|Visualization	YES
5440605	28473239	R.C.-H.	2	carried out the molecular epigenetic studies	carried out the molecular epigenetic studies	Performed the experiments	Investigation	YES
5440605	28473239	R.M.	2	carried out the molecular epigenetic studies|participated in the analysis|drafted the manuscript	carried out the molecular epigenetic studies	Performed the experiments	Investigation	YES
5440605	28473239	R.M.	2	carried out the molecular epigenetic studies|participated in the analysis|drafted the manuscript	participated in the analysis	-	-	NO
5440605	28473239	R.M.	2	carried out the molecular epigenetic studies|participated in the analysis|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5440605	28473239	S.B.	2	drafted the manuscript|performed the statistical analysis and prepared the tables/figures	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5440605	28473239	S.B.	2	drafted the manuscript|performed the statistical analysis and prepared the tables/figures	performed the statistical analysis and prepared the tables/figures	Analyzed the data	Formal analysis|Visualization	YES
5440605	28473239	S.L.	2	participated in the analysis	participated in the analysis	-	-	NO
5440605	28473239	X.L.	2	participated in the analysis	participated in the analysis	-	-	NO
5440605	28473239	Y-C.C.	2	participated in the analysis	participated in the analysis	-	-	NO
5440605	28473239	Y.C.	2	participated in the study design and/or collected the samples/physiological measurements	participated in the study design and/or collected the samples/physiological measurements	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5440605	28473239	Y.L.	2	participated in the study design and/or collected the samples/physiological measurements	participated in the study design and/or collected the samples/physiological measurements	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5440605	28473239	Y.P.	2	participated in the study design and/or collected the samples/physiological measurements	participated in the study design and/or collected the samples/physiological measurements	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5440605	28473239	Y.W.	2	participated in the analysis	participated in the analysis	-	-	NO
5511831	28769956	AR	2	helped in figures	helped in figures	-	Visualization	YES
5511831	28769956	All authors	2	revised the ms and approved it for publication	revised the ms and approved it for publication	Wrote the paper	Writing - Review & Editing	YES
5511831	28769956	CB	2	conceived and wrote the manuscript	conceived and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5511831	28769956	SF	2	conceived and wrote the manuscript	conceived and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5511831	28769956	SV	2	conceived and wrote the manuscript	conceived and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4723720	26900460	Felicity Page	7	literature search, writing the paper	literature search, writing the paper	Wrote the paper	Formal analysis|Writing - Original Draft	YES
4723720	26900460	Olfunso Adedeji	7	writing the paper	writing the paper	Wrote the paper	Writing - Original Draft	YES
4508673	26194348	CK	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4404248	25893832	CZ	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404248	25893832	CZ	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4404248	25893832	LW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404248	25893832	LW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404248	25893832	LW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404248	25893832	LW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404248	25893832	LW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404248	25893832	PG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4404248	25893832	PG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404248	25893832	SZ	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404248	25893832	WX	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5419355	28970374	Both authors	2	were involved in the conceptualization and writing of the article material	were involved in the conceptualization and writing of the article material	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4466483	26125027	Chao Sun	2	contributed equally to this work and should be considered co-first authors	contributed equally to this work and should be considered co-first authors	-	-	NO
4466483	26125027	Ruixia Zeng	2	contributed equally to this work and should be considered co-first authors	contributed equally to this work and should be considered co-first authors	-	-	NO
5440625	28479289	EWCC	2	analyzed the data and contributed to manuscript writing	analyzed the data and contributed to manuscript writing	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5440625	28479289	HWZ	2	performed cre strain identification and phenotypic characterization	performed cre strain identification and phenotypic characterization	Performed the experiments	Investigation	YES
5440625	28479289	JPL	2	performed cre strain identification and phenotypic characterization	performed cre strain identification and phenotypic characterization	Performed the experiments	Investigation	YES
5440625	28479289	KL	2	performed cre strain identification and phenotypic characterization	performed cre strain identification and phenotypic characterization	Performed the experiments	Investigation	YES
5440625	28479289	LZL	2	performed molecular characterization of all cre strains	performed molecular characterization of all cre strains	Performed the experiments	Investigation	YES
5440625	28479289	RZ	2	designed research and collected all the cre strains	designed research and collected all the cre strains	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5440625	28479289	SC	2	designed the research, supervised the progress of the study and wrote the manuscript	designed the research, supervised the progress of the study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Original Draft	YES
5440625	28479289	YF	2	performed cre strain identification and phenotypic characterization	performed cre strain identification and phenotypic characterization	Performed the experiments	Investigation	YES
5440625	28479289	YL	2	performed cre strain identification and phenotypic characterization	performed cre strain identification and phenotypic characterization	Performed the experiments	Investigation	YES
5223329	28068897	AG	7	histological and immunohistochemical analysis, final approval of manuscript	histological and immunohistochemical analysis, final approval of manuscript	Performed the experiments	Investigation	YES
5223329	28068897	AKP	7	collection, interpretation and assembly of data, manuscript writing, final approval of manuscript	collection, interpretation and assembly of data, manuscript writing, final approval of manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5223329	28068897	BGK	7	conception and design of the study, collection, analysis and interpretation of data, manuscript writing, final approval of manuscript	conception and design of the study, collection, analysis and interpretation of data, manuscript writing, final approval of manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5223329	28068897	LPK	7	design of the study, interpretation of data, final approval of manuscript	design of the study, interpretation of data, final approval of manuscript	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5223329	28068897	MK	7	western blot and qrt-pcr analysis, interpretation of data, final approval of manuscript	western blot and qrt-pcr analysis, interpretation of data, final approval of manuscript	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5223329	28068897	PS	7	analysis and interpretation of data, final approval of manuscript	analysis and interpretation of data, final approval of manuscript	Analyzed the data	Formal analysis	YES
6348445	30511833	A.G.K.	2	contributed equally	contributed equally	-	-	NO
6348445	30511833	C.F.M.	2	contributed equally	contributed equally	-	-	NO
6348445	30511833	C.P.M.	2	contributed equally	contributed equally	-	-	NO
6348445	30511833	K.A.R.	2	contributed equally	contributed equally	-	-	NO
6348445	30511833	SS	2	contributed equally	contributed equally	-	-	NO
4848790	27127532	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4848790	27127532	GC	2	contributed equally to this paper, conceived and wrote the manuscript	contributed equally to this paper, conceived and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4848790	27127532	GDG	2	wrote paragraphs of manuscript and collected references	wrote paragraphs of manuscript and collected references	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4848790	27127532	GdE	2	contributed equally to this paper, conceived and wrote the manuscript	contributed equally to this paper, conceived and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4848790	27127532	IS	2	wrote paragraphs of manuscript and collected references	wrote paragraphs of manuscript and collected references	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4848790	27127532	NG	2	wrote paragraphs of manuscript and collected references|contributed to first revisions	wrote paragraphs of manuscript and collected references	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4848790	27127532	NG	2	wrote paragraphs of manuscript and collected references|contributed to first revisions	contributed to first revisions	Wrote the paper	Writing - Review & Editing	YES
4848790	27127532	PP	2	wrote paragraphs of manuscript and collected references	wrote paragraphs of manuscript and collected references	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4848790	27127532	PV	2	wrote paragraphs of manuscript and collected references	wrote paragraphs of manuscript and collected references	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4848790	27127532	SS	2	wrote paragraphs of manuscript and collected references|contributed to first revisions	wrote paragraphs of manuscript and collected references	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4848790	27127532	SS	2	wrote paragraphs of manuscript and collected references|contributed to first revisions	contributed to first revisions	Wrote the paper	Writing - Review & Editing	YES
4848790	27127532	VV	2	critically revised all manuscript steps	critically revised all manuscript steps	Wrote the paper	Writing - Review & Editing	YES
5511834	28769946	All the authors	2	were involved in many discussion and revised the manuscript	were involved in many discussion and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5511834	28769946	CM	2	conducted experiments and data acquisition|modified the manuscript	conducted experiments and data acquisition	Performed the experiments	Investigation	YES
5511834	28769946	CM	2	conducted experiments and data acquisition|modified the manuscript	modified the manuscript	Wrote the paper	Writing - Review & Editing	YES
5511834	28769946	XK	2	planned the research|modified the manuscript	planned the research	Conceived and designed the experiments	Conceptualization	YES
5511834	28769946	XK	2	planned the research|modified the manuscript	modified the manuscript	Wrote the paper	Writing - Review & Editing	YES
5511834	28769946	ZS	2	conducted experiments and data acquisition	conducted experiments and data acquisition	Performed the experiments	Investigation	YES
5511834	28769946	ZZ	2	conducted experiments and data acquisition|wrote the manuscript closely with all authors	conducted experiments and data acquisition	Performed the experiments	Investigation	YES
5511834	28769946	ZZ	2	conducted experiments and data acquisition|wrote the manuscript closely with all authors	wrote the manuscript closely with all authors	Wrote the paper	Writing - Original Draft	YES
4509891	26198347	The authors	2	jointly conceived and wrote this commentary	jointly conceived and wrote this commentary	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4723730	26900464	Alessia Caleo	2	critically reviewed the manuscript for important intellectual content and approved the final version of the manuscript to be submitted	critically reviewed the manuscript for important intellectual content and approved the final version of the manuscript to be submitted	Wrote the paper	Writing - Review & Editing	YES
4723730	26900464	DAntonio	2	critically reviewed the manuscript for important intellectual content and approved the final version of the manuscript to be submitted	critically reviewed the manuscript for important intellectual content and approved the final version of the manuscript to be submitted	Wrote the paper	Writing - Review & Editing	YES
4723730	26900464	Maria Addesso	2	critically reviewed the manuscript for important intellectual content and approved the final version of the manuscript to be submitted	critically reviewed the manuscript for important intellectual content and approved the final version of the manuscript to be submitted	Wrote the paper	Writing - Review & Editing	YES
4723730	26900464	Maurizio Guida	2	critically reviewed the manuscript for important intellectual content and approved the final version of the manuscript to be submitted	critically reviewed the manuscript for important intellectual content and approved the final version of the manuscript to be submitted	Wrote the paper	Writing - Review & Editing	YES
4723730	26900464	Pio Zeppa	2	critically reviewed the manuscript for important intellectual content and approved the final version of the manuscript to be submitted	critically reviewed the manuscript for important intellectual content and approved the final version of the manuscript to be submitted	Wrote the paper	Writing - Review & Editing	YES
3528076	23284596	AL	2	participated and contributed to all phases of the study	participated and contributed to all phases of the study	-	-	NO
3528076	23284596	JMP	2	participated and contributed to all phases of the study	participated and contributed to all phases of the study	-	-	NO
3528076	23284596	SJE	2	participated and contributed to all phases of the study	participated and contributed to all phases of the study	-	-	NO
4404249	25894385	AJS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404249	25894385	AJS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404249	25894385	BY	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4404249	25894385	BY	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404249	25894385	DK	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404249	25894385	DK	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404249	25894385	DK	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404249	25894385	DK	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404249	25894385	DRJ	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404249	25894385	FA	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404249	25894385	FA	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404249	25894385	FA	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404249	25894385	NJC	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404249	25894385	NJC	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404249	25894385	PW	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4404249	25894385	PW	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404249	25894385	SJH	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4723733	26900458	Ren Chong Xi	2	has been involved in drafting the manuscript and revising it critically for important intellectual content	has been involved in drafting the manuscript and revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4723733	26900458	Yin Rui Sheng	2	has made substantial contributions to conception and design	has made substantial contributions to conception and design	Conceived and designed the experiments	Conceptualization	YES
5223348	28068916	CC	2	designed the algorithm and database|performed the analysis|prepared the manuscript	designed the algorithm and database	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
5223348	28068916	CC	2	designed the algorithm and database|performed the analysis|prepared the manuscript	performed the analysis	Performed the experiments	Investigation	YES
5223348	28068916	CC	2	designed the algorithm and database|performed the analysis|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5223348	28068916	CCL	2	designed the algorithm and database|prepared the manuscript	designed the algorithm and database	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
5223348	28068916	CCL	2	designed the algorithm and database|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5223348	28068916	CCY	2	designed the algorithm and database|performed the analysis|prepared the manuscript|contributed to the literature study	designed the algorithm and database	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
5223348	28068916	CCY	2	designed the algorithm and database|performed the analysis|prepared the manuscript|contributed to the literature study	performed the analysis	Performed the experiments	Investigation	YES
5223348	28068916	CCY	2	designed the algorithm and database|performed the analysis|prepared the manuscript|contributed to the literature study	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5223348	28068916	CCY	2	designed the algorithm and database|performed the analysis|prepared the manuscript|contributed to the literature study	contributed to the literature study	-	-	NO
5223348	28068916	EHA	2	prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5223348	28068916	JJWC	2	prepared the manuscript|contributed to the literature study	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5223348	28068916	JJWC	2	prepared the manuscript|contributed to the literature study	contributed to the literature study	-	-	NO
5223348	28068916	MHC	2	performed the analysis|prepared the manuscript	performed the analysis	Performed the experiments	Investigation	YES
5223348	28068916	MHC	2	performed the analysis|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5223348	28068916	SYL	2	performed the analysis|contributed to the literature study	performed the analysis	Performed the experiments	Investigation	YES
5223348	28068916	SYL	2	performed the analysis|contributed to the literature study	contributed to the literature study	-	-	NO
5419356	28970383	CJ	2	conceptualized the study	conceptualized the study	Conceived and designed the experiments	Conceptualization	YES
5419356	28970383	HC	2	conceptualized the study|oversaw its execution	conceptualized the study	Conceived and designed the experiments	Conceptualization	YES
5419356	28970383	HC	2	conceptualized the study|oversaw its execution	oversaw its execution	Performed the experiments	Investigation|Supervision	YES
5419356	28970383	JP	2	oversaw its execution	oversaw its execution	Performed the experiments	Investigation|Supervision	YES
5419356	28970383	MS	2	conceptualized and executed the scoring and analysis of the data	conceptualized and executed the scoring and analysis of the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation	YES
5419356	28970383	SP	2	conceptualized and executed the scoring and analysis of the data	conceptualized and executed the scoring and analysis of the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation	YES
5419356	28970383	SS	2	conceptualized the study|conceptualized and executed the scoring and analysis of the data|drafted the manuscript, and all authors contributed substantially to the final draft	conceptualized the study	Conceived and designed the experiments	Conceptualization	YES
5419356	28970383	SS	2	conceptualized the study|conceptualized and executed the scoring and analysis of the data|drafted the manuscript, and all authors contributed substantially to the final draft	conceptualized and executed the scoring and analysis of the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation	YES
5419356	28970383	SS	2	conceptualized the study|conceptualized and executed the scoring and analysis of the data|drafted the manuscript, and all authors contributed substantially to the final draft	drafted the manuscript, and all authors contributed substantially to the final draft	Wrote the paper	Writing - Original Draft	YES
5511847	28769958	H-YL	2	performed the experiments, analyzed the data	performed the experiments, analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5511847	28769958	SJ	2	designed the experiments|performed the experiments, analyzed the data|wrote the article	designed the experiments	Conceived and designed the experiments	Methodology	YES
5511847	28769958	SJ	2	designed the experiments|performed the experiments, analyzed the data|wrote the article	performed the experiments, analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5511847	28769958	SJ	2	designed the experiments|performed the experiments, analyzed the data|wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
5474428	28089792	AB	2	performed histological analyses	performed histological analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5474428	28089792	AM	2	designed and organized the ex vivo experiments	designed and organized the ex vivo experiments	Conceived and designed the experiments	Methodology	YES
5474428	28089792	All authors	2	contributed to acquisition, analysis, and interpretation of data	contributed to acquisition, analysis, and interpretation of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5474428	28089792	BLO	2	performed cytofluorimetric analyses	performed cytofluorimetric analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5474428	28089792	ER	2	designed and organized the ex vivo experiments	designed and organized the ex vivo experiments	Conceived and designed the experiments	Methodology	YES
5474428	28089792	LM	2	performed histological analyses|designed the study	performed histological analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5474428	28089792	LM	2	performed histological analyses|designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5474428	28089792	MB	2	designed the study|organized the experiments and wrote the paper	designed the study	Conceived and designed the experiments	Methodology	YES
5474428	28089792	MB	2	designed the study|organized the experiments and wrote the paper	organized the experiments and wrote the paper	Wrote the paper	Writing - Original Draft	YES
5474428	28089792	PF	2	managed the mouse model|performed molecular analyses	managed the mouse model	Performed the experiments	Methodology	YES
5474428	28089792	PF	2	managed the mouse model|performed molecular analyses	performed molecular analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5474428	28089792	SP	2	performed the ex-vivo experiments|designed and organized the ex vivo experiments	performed the ex-vivo experiments	Performed the experiments	Investigation	YES
5474428	28089792	SP	2	performed the ex-vivo experiments|designed and organized the ex vivo experiments	designed and organized the ex vivo experiments	Conceived and designed the experiments	Methodology	YES
5474428	28089792	VM	2	performed histological analyses|performed treadmill functional analyses and statistical analyses|managed the mouse model|designed the study|organized the experiments and wrote the paper	performed histological analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5474428	28089792	VM	2	performed histological analyses|performed treadmill functional analyses and statistical analyses|managed the mouse model|designed the study|organized the experiments and wrote the paper	performed treadmill functional analyses and statistical analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5474428	28089792	VM	2	performed histological analyses|performed treadmill functional analyses and statistical analyses|managed the mouse model|designed the study|organized the experiments and wrote the paper	managed the mouse model	Performed the experiments	Methodology	YES
5474428	28089792	VM	2	performed histological analyses|performed treadmill functional analyses and statistical analyses|managed the mouse model|designed the study|organized the experiments and wrote the paper	designed the study	Conceived and designed the experiments	Methodology	YES
5474428	28089792	VM	2	performed histological analyses|performed treadmill functional analyses and statistical analyses|managed the mouse model|designed the study|organized the experiments and wrote the paper	organized the experiments and wrote the paper	Wrote the paper	Writing - Original Draft	YES
4509892	26198350	All authors	2	contributed to the writing of the manuscript, and all approved the final draft	contributed to the writing of the manuscript, and all approved the final draft	Wrote the paper	Writing - Original Draft	YES
4509892	26198350	CC	2	wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
4509892	26198350	JMB	2	wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
4723734	26900462	Bogdan Deleanu	7	study concept, data collection, data analysis	study concept, data collection, data analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation	YES
4723734	26900462	Dinu Vermesan	7	data collection, data analysis	data collection, data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4723734	26900462	Eleftherios Tsiridis	7	data analysis	data analysis	Analyzed the data	Formal analysis	YES
4723734	26900462	Lucian Honcea	7	writing the paper, data analysis	writing the paper, data analysis	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4723734	26900462	Mihai Mioc Lazar	7	writing the paper, data analysis	writing the paper, data analysis	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4723734	26900462	Radu Prejbeanu	7	data collection, data analysis	data collection, data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4723734	26900462	Vlad Predescu	7	data analysis	data analysis	Analyzed the data	Formal analysis	YES
3514811	23226981	R. Skripitz	2	are contributed equally to this work	are contributed equally to this work	-	-	NO
3514811	23226981	Y. Haba	2	are contributed equally to this work	are contributed equally to this work	-	-	NO
4866405	27182275	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4866405	27182275	SS	2	prepared the original manuscript and contributed to subsequent revisions	prepared the original manuscript and contributed to subsequent revisions	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4866405	27182275	SW	2	prepared the original manuscript and contributed to subsequent revisions	prepared the original manuscript and contributed to subsequent revisions	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4866405	27182275	WM	2	prepared the original manuscript and contributed to subsequent revisions	prepared the original manuscript and contributed to subsequent revisions	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4404250	25894587	AA	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404250	25894587	AA	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404250	25894587	CK	PLoS5	Analyzed the data|Wrote the paper|Data acquisition	Analyzed the data	Analyzed the data	Formal analysis	YES
4404250	25894587	CK	PLoS5	Analyzed the data|Wrote the paper|Data acquisition	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404250	25894587	CK	PLoS5	Analyzed the data|Wrote the paper|Data acquisition	Data acquisition	Performed the experiments	Investigation	YES
4404250	25894587	CW	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404250	25894587	DRA	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404250	25894587	DRA	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404250	25894587	DRA	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404250	25894587	JZ	PLoS5	Data acquisition	Data acquisition	Performed the experiments	Investigation	YES
4404250	25894587	LS	PLoS5	Data acquisition	Data acquisition	Performed the experiments	Investigation	YES
4404250	25894587	MB	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404250	25894587	MW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404250	25894587	MW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404250	25894587	MW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404250	25894587	PUH	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404250	25894587	UR	PLoS5	Data acquisition	Data acquisition	Performed the experiments	Investigation	YES
5223358	28068899	AN	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5223358	28068899	KT	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5223358	28068899	KT	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5223358	28068899	SB	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5223358	28068899	SB	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5223358	28068899	ST	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5223358	28068899	YG	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5223358	28068899	all authors	PLoS5	Edited and proofed the paper	Edited and proofed the paper	Wrote the paper	Writing - Review & Editing	YES
5511852	28769945	All of the authors	2	critically revised and approved the final manuscript	critically revised and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5511852	28769945	CF	2	originally conceived the experiment|identified and enrolled the farming communities	originally conceived the experiment	Conceived and designed the experiments	Conceptualization	YES
5511852	28769945	CF	2	originally conceived the experiment|identified and enrolled the farming communities	identified and enrolled the farming communities	Performed the experiments	Investigation	YES
5511852	28769945	CM	2	conducted focus group discussion and supervised field evaluations|analyzed metric traits and farmer traits	conducted focus group discussion and supervised field evaluations	Performed the experiments	Investigation|Supervision	YES
5511852	28769945	CM	2	conducted focus group discussion and supervised field evaluations|analyzed metric traits and farmer traits	analyzed metric traits and farmer traits	Analyzed the data	Formal analysis	YES
5511852	28769945	DM	2	identified and enrolled the farming communities|conducted focus group discussion and supervised field evaluations	identified and enrolled the farming communities	Performed the experiments	Investigation	YES
5511852	28769945	DM	2	identified and enrolled the farming communities|conducted focus group discussion and supervised field evaluations	conducted focus group discussion and supervised field evaluations	Performed the experiments	Investigation|Supervision	YES
5511852	28769945	EF	2	analyzed metric traits and farmer traits	analyzed metric traits and farmer traits	Analyzed the data	Formal analysis	YES
5511852	28769945	MD	2	supervised data analyses|conducted genotypic and statistical data analysis, produced figures, and drafted the manuscript	supervised data analyses	Analyzed the data	Formal analysis|Supervision	YES
5511852	28769945	MD	2	supervised data analyses|conducted genotypic and statistical data analysis, produced figures, and drafted the manuscript	conducted genotypic and statistical data analysis, produced figures, and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Visualization|Writing - Original Draft	YES
5511852	28769945	MP	2	originally conceived the experiment|supervised data analyses	originally conceived the experiment	Conceived and designed the experiments	Conceptualization	YES
5511852	28769945	MP	2	originally conceived the experiment|supervised data analyses	supervised data analyses	Analyzed the data	Formal analysis|Supervision	YES
5511852	28769945	YK	2	identified and enrolled the farming communities|conducted focus group discussion and supervised field evaluations|analyzed metric traits and farmer traits	identified and enrolled the farming communities	Performed the experiments	Investigation	YES
5511852	28769945	YK	2	identified and enrolled the farming communities|conducted focus group discussion and supervised field evaluations|analyzed metric traits and farmer traits	conducted focus group discussion and supervised field evaluations	Performed the experiments	Investigation|Supervision	YES
5511852	28769945	YK	2	identified and enrolled the farming communities|conducted focus group discussion and supervised field evaluations|analyzed metric traits and farmer traits	analyzed metric traits and farmer traits	Analyzed the data	Formal analysis	YES
5474433	28094237	A.F.	2	performed experiments and data analysis|interpreted the results|wrote the manuscript	performed experiments and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5474433	28094237	A.F.	2	performed experiments and data analysis|interpreted the results|wrote the manuscript	interpreted the results	Analyzed the data	Formal analysis	YES
5474433	28094237	A.F.	2	performed experiments and data analysis|interpreted the results|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5474433	28094237	APD	2	performed experiments and data analysis	performed experiments and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5474433	28094237	J.Z.	2	performed experiments and data analysis|interpreted the results|wrote the manuscript	performed experiments and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5474433	28094237	J.Z.	2	performed experiments and data analysis|interpreted the results|wrote the manuscript	interpreted the results	Analyzed the data	Formal analysis	YES
5474433	28094237	J.Z.	2	performed experiments and data analysis|interpreted the results|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5474433	28094237	K.D.	2	interpreted the results	interpreted the results	Analyzed the data	Formal analysis	YES
5474433	28094237	P.Y.S.	2	interpreted the results|wrote the manuscript	interpreted the results	Analyzed the data	Formal analysis	YES
5474433	28094237	P.Y.S.	2	interpreted the results|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5474433	28094237	S.J.W.	2	interpreted the results|wrote the manuscript	interpreted the results	Analyzed the data	Formal analysis	YES
5474433	28094237	S.J.W.	2	interpreted the results|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5474433	28094237	X.X.	2	performed experiments and data analysis	performed experiments and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4574035	26381439	All	2	listed authors concur with the submission	listed authors concur with the submission	-	-	NO
4574035	26381439	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4574035	26381439	BCMH	2	have contributed substantially to the conception and design of the study|have made a substantial contribution to the collection of the data	have contributed substantially to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4574035	26381439	BCMH	2	have contributed substantially to the conception and design of the study|have made a substantial contribution to the collection of the data	have made a substantial contribution to the collection of the data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4574035	26381439	HAD	2	have contributed substantially to the conception and design of the study|have made a substantial contribution to the collection of the data	have contributed substantially to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4574035	26381439	HAD	2	have contributed substantially to the conception and design of the study|have made a substantial contribution to the collection of the data	have made a substantial contribution to the collection of the data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4574035	26381439	KB	2	have contributed substantially to the conception and design of the study	have contributed substantially to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4574035	26381439	RFR	2	have contributed substantially to the conception and design of the study	have contributed substantially to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4574035	26381439	RS	2	have contributed substantially to the conception and design of the study	have contributed substantially to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4574035	26381439	SC	2	have made a substantial contribution to the collection of the data	have made a substantial contribution to the collection of the data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4574035	26381439	The authors	2	have contributed substantially to the conception and design of the study|have made a substantial contribution to the collection of the data	have contributed substantially to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4574035	26381439	The authors	2	have contributed substantially to the conception and design of the study|have made a substantial contribution to the collection of the data	have made a substantial contribution to the collection of the data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4574035	26381439	WAN	2	have contributed substantially to the conception and design of the study	have contributed substantially to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4869330	27190544	AA	2	were all involved in the study design, studies search, data extraction and analysis	were all involved in the study design, studies search, data extraction and analysis	Conceived and designed the experiments|Analyzed the data	Data curation|Formal analysis|Methodology	YES
4869330	27190544	Both authors	2	contributed equally to preparing this content|read and approved the final manuscript	contributed equally to preparing this content	-	-	NO
4869330	27190544	Both authors	2	contributed equally to preparing this content|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4869330	27190544	RO	2	were all involved in the study design, studies search, data extraction and analysis	were all involved in the study design, studies search, data extraction and analysis	Conceived and designed the experiments|Analyzed the data	Data curation|Formal analysis|Methodology	YES
4724022	26900456	Eduardo Cordero-Estrada	7	Data Collection, writing. Victor	Data Collection, writing. Victor	Performed the experiments|Wrote the paper	Investigation	YES
4724022	26900456	Eduardo Sotelo-Anaya	7	Data Collection, writing	Data Collection, writing	Performed the experiments|Wrote the paper	Investigation	YES
4724022	26900456	Felipe Ploneda-Valencia	7	Study design, Data collection, data analysis, writing	Study design, Data collection, data analysis, writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology	YES
4724022	26900456	Hector Silva-Baez	7	Data Collection, writing	Data Collection, writing	Performed the experiments|Wrote the paper	Investigation	YES
4724022	26900456	Hugo Sainz-Escarrega	7	Data Collection, writing. Cesar	Data Collection, writing. Cesar	Performed the experiments|Wrote the paper	Investigation	YES
4724022	26900456	Mariana Gallo-Morales	7	Web search, data collection	Web search, data collection	Performed the experiments	Investigation	YES
4724022	26900456	Mizraim Ixtabalan-Escalante	7	Data Collection, writing	Data Collection, writing	Performed the experiments|Wrote the paper	Investigation	YES
4724022	26900456	Pedro Coello-Ramirez	7	Data Collection, writing. Eddy	Data Collection, writing. Eddy	Performed the experiments|Wrote the paper	Investigation	YES
4468276	26137471	Stuart J. Mills	2	contributed equally to this work	contributed equally to this work	-	-	NO
4468276	26137471	T. S. Kirby	2	contributed equally to this work	contributed equally to this work	-	-	NO
5419358	28970376	Both authors	2	participated in the study design, the construction of the interview guide, the consensus analysis, the revision of the manuscript, and both approved the final manuscript	participated in the study design, the construction of the interview guide, the consensus analysis, the revision of the manuscript, and both approved the final manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
5419358	28970376	K.W.	2	performed the interviews, transcribed the interviews, performed the initial analysis of the interviews, and drafted major parts of the manuscript	performed the interviews, transcribed the interviews, performed the initial analysis of the interviews, and drafted major parts of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5419358	28970376	S.K.S.	2	made a separate analysis of the interviews and drafted some parts of the manuscript	made a separate analysis of the interviews and drafted some parts of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4404251	25893540	GT	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404251	25893540	JDH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404251	25893540	JDH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404251	25893540	JDH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404251	25893540	MK	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404251	25893540	NB	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404251	25893540	PGR	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404251	25893540	PGR	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4404251	25893540	SJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404251	25893540	SJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404251	25893540	SJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4509893	26198345	AL	2	contributed to the initial outline and subsequent drafts, added specific content and assisted in editing the final draft of the paper	contributed to the initial outline and subsequent drafts, added specific content and assisted in editing the final draft of the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4509893	26198345	DK	2	contributed to the initial outline and subsequent drafts, added specific content and assisted in editing the final draft of the paper	contributed to the initial outline and subsequent drafts, added specific content and assisted in editing the final draft of the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4509893	26198345	JP	2	contributed to the initial outline and subsequent drafts, added specific content and assisted in editing the final draft of the paper	contributed to the initial outline and subsequent drafts, added specific content and assisted in editing the final draft of the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4509893	26198345	KHM	2	conceptualized and wrote the first draft of the manuscript and addressed reviewer comments	conceptualized and wrote the first draft of the manuscript and addressed reviewer comments	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
4509893	26198345	MW	2	contributed to the initial outline and subsequent drafts, added specific content and assisted in editing the final draft of the paper	contributed to the initial outline and subsequent drafts, added specific content and assisted in editing the final draft of the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4509893	26198345	RG	2	contributed to the initial outline and subsequent drafts, added specific content and assisted in editing the final draft of the paper	contributed to the initial outline and subsequent drafts, added specific content and assisted in editing the final draft of the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4509893	26198345	SC	2	contributed to the initial outline and subsequent drafts, added specific content and assisted in editing the final draft of the paper	contributed to the initial outline and subsequent drafts, added specific content and assisted in editing the final draft of the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4509893	26198345	SH	2	contributed to the initial outline and subsequent drafts, added specific content and assisted in editing the final draft of the paper	contributed to the initial outline and subsequent drafts, added specific content and assisted in editing the final draft of the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4724023	26900459	Xiaoyi Sun	2	designed this study	designed this study	Conceived and designed the experiments	Methodology	YES
4724023	26900459	Zhi Li	2	collected data and wrote this manuscript	collected data and wrote this manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5223370	28068911	ARM	2	prepared samples for the gbs assay and collected phenotypic data	prepared samples for the gbs assay and collected phenotypic data	Performed the experiments	Investigation	YES
5223370	28068911	CL	2	designed the experiment|established the germplasm collection|critically revised the manuscript	designed the experiment	Conceived and designed the experiments	Methodology	YES
5223370	28068911	CL	2	designed the experiment|established the germplasm collection|critically revised the manuscript	established the germplasm collection	-	-	NO
5223370	28068911	CL	2	designed the experiment|established the germplasm collection|critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5223370	28068911	EC	2	performed the analyses|critically revised the manuscript	performed the analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5223370	28068911	EC	2	performed the analyses|critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5223370	28068911	LR	2	designed the experiment|established the germplasm collection|critically revised the manuscript	designed the experiment	Conceived and designed the experiments	Methodology	YES
5223370	28068911	LR	2	designed the experiment|established the germplasm collection|critically revised the manuscript	established the germplasm collection	-	-	NO
5223370	28068911	LR	2	designed the experiment|established the germplasm collection|critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5223370	28068911	RM	2	prepared samples for the gbs assay and collected phenotypic data	prepared samples for the gbs assay and collected phenotypic data	Performed the experiments	Investigation	YES
5223370	28068911	SP	2	designed the experiment|performed the analyses|wrote the manuscript	designed the experiment	Conceived and designed the experiments	Methodology	YES
5223370	28068911	SP	2	designed the experiment|performed the analyses|wrote the manuscript	performed the analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5223370	28068911	SP	2	designed the experiment|performed the analyses|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5223370	28068911	VR	2	performed the analyses	performed the analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5223370	28068911	VZ	2	prepared samples for the gbs assay and collected phenotypic data	prepared samples for the gbs assay and collected phenotypic data	Performed the experiments	Investigation	YES
4938927	27398087	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4938927	27398087	BN	2	contributed to study design and data collection	contributed to study design and data collection	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources	YES
4938927	27398087	JB	2	collected additional follow-up data, analysed the data and drafted the manuscript	collected additional follow-up data, analysed the data and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4938927	27398087	KHDSS	2	the survey/clinic linkages and the linkages with other clinics	the survey/clinic linkages and the linkages with other clinics	Performed the experiments	Investigation	YES
4938927	27398087	NF	2	conceived and oversaw implementation of the art clinical cohort	conceived and oversaw implementation of the art clinical cohort	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Supervision	YES
4938927	27398087	OK	2	supervised data cleaning and analysis and reviewed and edited all drafts of the manuscript	supervised data cleaning and analysis and reviewed and edited all drafts of the manuscript	Analyzed the data|Wrote the paper	Data curation|Formal analysis|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
4938927	27398087	TT	2	contributed to study design and data collection	contributed to study design and data collection	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources	YES
5474509	28139439	Ann-Charlotte Kristoffersson	7	performed experiments and analyzed data	performed experiments and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5474509	28139439	Cees van Kooten	7	provided gbm and assisted in writing the paper	provided gbm and assisted in writing the paper	Wrote the paper	Writing - Original Draft	YES
5474509	28139439	Diana Karpman	7	designed the project, analyzed data and wrote the paper	designed the project, analyzed data and wrote the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5474509	28139439	Jorgen Wieslander	7	provided gbm	provided gbm	-	-	NO
5474509	28139439	Matthias Morgelin	7	performed experiments and analyzed data	performed experiments and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5474509	28139439	Minola Manea Hedstrom	7	performed experiments and analyzed data	performed experiments and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5474509	28139439	Ramesh Tati	7	performed the research, analyzed data and wrote the paper	performed the research, analyzed data and wrote the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5511853	28769948	RS-P	2	designed and supervised the experiments and contributed to the writing of the manuscript	designed and supervised the experiments and contributed to the writing of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Original Draft	YES
4509894	26198344	All authors	2	contributed to the overall content plan	contributed to the overall content plan	-	-	NO
4509894	26198344	FV	2	did the first draft together, and all co-authors have contributed to subsequent drafts and revisions and have signed off on the final manuscript	did the first draft together, and all co-authors have contributed to subsequent drafts and revisions and have signed off on the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4509894	26198344	LGB	2	did the first draft together, and all co-authors have contributed to subsequent drafts and revisions and have signed off on the final manuscript	did the first draft together, and all co-authors have contributed to subsequent drafts and revisions and have signed off on the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4404252	25893888	GA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404252	25893888	GA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404252	25893888	GA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404252	25893888	JG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4404252	25893888	JLR	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4404252	25893888	TY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404252	25893888	TY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404252	25893888	TY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404252	25893888	TY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4940870	27408611	All	2	others contributed to drafting the manuscript	others contributed to drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
4940870	27408611	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4940870	27408611	DOB	2	conceived the idea for the study and planned the analysis	conceived the idea for the study and planned the analysis	Conceived and designed the experiments	Conceptualization	YES
4940870	27408611	JG	2	conceived the idea for the study and planned the analysis	conceived the idea for the study and planned the analysis	Conceived and designed the experiments	Conceptualization	YES
4940870	27408611	JHM	2	conceived the idea for the study and planned the analysis|wrote the first draft of the manuscript|contributed equally to the study to be considered joint first authors	conceived the idea for the study and planned the analysis	Conceived and designed the experiments	Conceptualization	YES
4940870	27408611	JHM	2	conceived the idea for the study and planned the analysis|wrote the first draft of the manuscript|contributed equally to the study to be considered joint first authors	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
4940870	27408611	JHM	2	conceived the idea for the study and planned the analysis|wrote the first draft of the manuscript|contributed equally to the study to be considered joint first authors	contributed equally to the study to be considered joint first authors	-	-	NO
4940870	27408611	NF	2	conceived the idea for the study and planned the analysis	conceived the idea for the study and planned the analysis	Conceived and designed the experiments	Conceptualization	YES
4940870	27408611	TS	2	conceived the idea for the study and planned the analysis|performed the analyses|contributed equally to the study to be considered joint first authors	conceived the idea for the study and planned the analysis	Conceived and designed the experiments	Conceptualization	YES
4940870	27408611	TS	2	conceived the idea for the study and planned the analysis|performed the analyses|contributed equally to the study to be considered joint first authors	performed the analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4940870	27408611	TS	2	conceived the idea for the study and planned the analysis|performed the analyses|contributed equally to the study to be considered joint first authors	contributed equally to the study to be considered joint first authors	-	-	NO
4595415	26440507	A. Nolen	2	have received an unrestricted grant from eli lilly, the netherlands to perform the study	have received an unrestricted grant from eli lilly, the netherlands to perform the study	Performed the experiments	Investigation	YES
4595415	26440507	All authors	2	contributed to the final manuscript|read and approved the final manuscript	contributed to the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4595415	26440507	All authors	2	contributed to the final manuscript|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4595415	26440507	ER	2	performed the statistical analysis|managed the literature searches|wrote the first draft of the manuscript	performed the statistical analysis	Analyzed the data	Formal analysis	YES
4595415	26440507	ER	2	performed the statistical analysis|managed the literature searches|wrote the first draft of the manuscript	managed the literature searches	-	Formal analysis	YES
4595415	26440507	ER	2	performed the statistical analysis|managed the literature searches|wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
4595415	26440507	MH	2	performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
4595415	26440507	RK	2	wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
4595415	26440507	W.A.M.	2	declared no conflict of interest in relation to this study	declared no conflict of interest in relation to this study	-	-	NO
4595415	26440507	WN	2	designed the study and wrote the protocol|managed the literature searches	designed the study and wrote the protocol	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4595415	26440507	WN	2	designed the study and wrote the protocol|managed the literature searches	managed the literature searches	-	Formal analysis	YES
4595415	26440507	WV	2	designed the study and wrote the protocol	designed the study and wrote the protocol	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4468278	26137472	Paolo Longoni	2	contributed equally	contributed equally	-	-	NO
4468278	26137472	Sadhu Leelavathi	2	contributed equally	contributed equally	-	-	NO
5478201	28583742	E.C.	2	performed the experiments and analyzed the data|wrote the first draft of the manuscript and prepared the figures	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5478201	28583742	E.C.	2	performed the experiments and analyzed the data|wrote the first draft of the manuscript and prepared the figures	wrote the first draft of the manuscript and prepared the figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5478201	28583742	H.Y.	2	wrote the first draft of the manuscript and prepared the figures	wrote the first draft of the manuscript and prepared the figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5478201	28583742	J.Z.	2	conceived the research and designed the experiments|supervised the project|wrote the first draft of the manuscript and prepared the figures|other authors discussed and contributed to the writing of the manuscript	conceived the research and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5478201	28583742	J.Z.	2	conceived the research and designed the experiments|supervised the project|wrote the first draft of the manuscript and prepared the figures|other authors discussed and contributed to the writing of the manuscript	supervised the project	-	Supervision	YES
5478201	28583742	J.Z.	2	conceived the research and designed the experiments|supervised the project|wrote the first draft of the manuscript and prepared the figures|other authors discussed and contributed to the writing of the manuscript	wrote the first draft of the manuscript and prepared the figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5478201	28583742	J.Z.	2	conceived the research and designed the experiments|supervised the project|wrote the first draft of the manuscript and prepared the figures|other authors discussed and contributed to the writing of the manuscript	other authors discussed and contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5478201	28583742	L.C.	2	performed the experiments and analyzed the data|wrote the first draft of the manuscript and prepared the figures	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5478201	28583742	L.C.	2	performed the experiments and analyzed the data|wrote the first draft of the manuscript and prepared the figures	wrote the first draft of the manuscript and prepared the figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5478201	28583742	L.L.	2	conceived the research and designed the experiments|supervised the project|wrote the first draft of the manuscript and prepared the figures|other authors discussed and contributed to the writing of the manuscript	conceived the research and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5478201	28583742	L.L.	2	conceived the research and designed the experiments|supervised the project|wrote the first draft of the manuscript and prepared the figures|other authors discussed and contributed to the writing of the manuscript	supervised the project	-	Supervision	YES
5478201	28583742	L.L.	2	conceived the research and designed the experiments|supervised the project|wrote the first draft of the manuscript and prepared the figures|other authors discussed and contributed to the writing of the manuscript	wrote the first draft of the manuscript and prepared the figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5478201	28583742	L.L.	2	conceived the research and designed the experiments|supervised the project|wrote the first draft of the manuscript and prepared the figures|other authors discussed and contributed to the writing of the manuscript	other authors discussed and contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5478201	28583742	P.Z.	2	performed the experiments and analyzed the data|wrote the first draft of the manuscript and prepared the figures	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5478201	28583742	P.Z.	2	performed the experiments and analyzed the data|wrote the first draft of the manuscript and prepared the figures	wrote the first draft of the manuscript and prepared the figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5478201	28583742	S.J.	2	supervised the project|other authors discussed and contributed to the writing of the manuscript	supervised the project	-	Supervision	YES
5478201	28583742	S.J.	2	supervised the project|other authors discussed and contributed to the writing of the manuscript	other authors discussed and contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5512343	28769947	BC	2	interpreted the data and wrote the manuscript	interpreted the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5512343	28769947	BY	2	designed the experiments|interpreted the data and wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5512343	28769947	BY	2	designed the experiments|interpreted the data and wrote the manuscript	interpreted the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5512343	28769947	HC	2	conducted the experiments, collected and analyzed all data	conducted the experiments, collected and analyzed all data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5512343	28769947	JA	2	conducted the experiments, collected and analyzed all data|interpreted the data and wrote the manuscript	conducted the experiments, collected and analyzed all data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5512343	28769947	JA	2	conducted the experiments, collected and analyzed all data|interpreted the data and wrote the manuscript	interpreted the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5512343	28769947	WC	2	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5512343	28769947	ZH	2	conducted the experiments, collected and analyzed all data	conducted the experiments, collected and analyzed all data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5223410	28068921	All authors	PLoS52	contributed in the interpretation of results and approved the final manuscript	contributed in the interpretation of results and approved the final manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5223410	28068921	BG	PLoS52	conceived and designed the experiments|interpreted the results|contributed to the final editing of manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5223410	28068921	BG	PLoS52	conceived and designed the experiments|interpreted the results|contributed to the final editing of manuscript	interpreted the results	Analyzed the data	Formal analysis	YES
5223410	28068921	BG	PLoS52	conceived and designed the experiments|interpreted the results|contributed to the final editing of manuscript	contributed to the final editing of manuscript	Wrote the paper	Writing - Review & Editing	YES
5223410	28068921	BL	PLoS52	conceived and designed the experiments|interpreted the results|contributed to the final editing of manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5223410	28068921	BL	PLoS52	conceived and designed the experiments|interpreted the results|contributed to the final editing of manuscript	interpreted the results	Analyzed the data	Formal analysis	YES
5223410	28068921	BL	PLoS52	conceived and designed the experiments|interpreted the results|contributed to the final editing of manuscript	contributed to the final editing of manuscript	Wrote the paper	Writing - Review & Editing	YES
5223410	28068921	FL	PLoS52	conceived and designed the experiments|conducted field trials and data collections	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5223410	28068921	FL	PLoS52	conceived and designed the experiments|conducted field trials and data collections	conducted field trials and data collections	Performed the experiments	Investigation	YES
5223410	28068921	HJ	PLoS52	conceived and designed the experiments|developed the ril population|constructed the genetic linkage map and performed qtl analysis|interpreted the results|contributed to the final editing of manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5223410	28068921	HJ	PLoS52	conceived and designed the experiments|developed the ril population|constructed the genetic linkage map and performed qtl analysis|interpreted the results|contributed to the final editing of manuscript	developed the ril population	-	-	NO
5223410	28068921	HJ	PLoS52	conceived and designed the experiments|developed the ril population|constructed the genetic linkage map and performed qtl analysis|interpreted the results|contributed to the final editing of manuscript	constructed the genetic linkage map and performed qtl analysis	Performed the experiments	Investigation	YES
5223410	28068921	HJ	PLoS52	conceived and designed the experiments|developed the ril population|constructed the genetic linkage map and performed qtl analysis|interpreted the results|contributed to the final editing of manuscript	interpreted the results	Analyzed the data	Formal analysis	YES
5223410	28068921	HJ	PLoS52	conceived and designed the experiments|developed the ril population|constructed the genetic linkage map and performed qtl analysis|interpreted the results|contributed to the final editing of manuscript	contributed to the final editing of manuscript	Wrote the paper	Writing - Review & Editing	YES
5223410	28068921	HL	PLoS52	conceived and designed the experiments|constructed the genetic linkage map and performed qtl analysis|interpreted the results|contributed to the final editing of manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5223410	28068921	HL	PLoS52	conceived and designed the experiments|constructed the genetic linkage map and performed qtl analysis|interpreted the results|contributed to the final editing of manuscript	constructed the genetic linkage map and performed qtl analysis	Performed the experiments	Investigation	YES
5223410	28068921	HL	PLoS52	conceived and designed the experiments|constructed the genetic linkage map and performed qtl analysis|interpreted the results|contributed to the final editing of manuscript	interpreted the results	Analyzed the data	Formal analysis	YES
5223410	28068921	HL	PLoS52	conceived and designed the experiments|constructed the genetic linkage map and performed qtl analysis|interpreted the results|contributed to the final editing of manuscript	contributed to the final editing of manuscript	Wrote the paper	Writing - Review & Editing	YES
5223410	28068921	LH	PLoS52	performed genotyping	performed genotyping	Performed the experiments	Investigation	YES
5223410	28068921	MKP	PLoS52	interpreted the results|contributed to the final editing of manuscript	interpreted the results	Analyzed the data	Formal analysis	YES
5223410	28068921	MKP	PLoS52	interpreted the results|contributed to the final editing of manuscript	contributed to the final editing of manuscript	Wrote the paper	Writing - Review & Editing	YES
5223410	28068921	RKV	PLoS52	interpreted the results|contributed to the final editing of manuscript	interpreted the results	Analyzed the data	Formal analysis	YES
5223410	28068921	RKV	PLoS52	interpreted the results|contributed to the final editing of manuscript	contributed to the final editing of manuscript	Wrote the paper	Writing - Review & Editing	YES
5223410	28068921	WC	PLoS52	performed genotyping	performed genotyping	Performed the experiments	Investigation	YES
5223410	28068921	XJ	PLoS52	conducted field trials and data collections	conducted field trials and data collections	Performed the experiments	Investigation	YES
5223410	28068921	XL	PLoS52	performed genotyping	performed genotyping	Performed the experiments	Investigation	YES
5223410	28068921	XR	PLoS52	developed the ril population|conducted field trials and data collections	developed the ril population	-	-	NO
5223410	28068921	XR	PLoS52	developed the ril population|conducted field trials and data collections	conducted field trials and data collections	Performed the experiments	Investigation	YES
5223410	28068921	XZ	PLoS52	conceived and designed the experiments|conducted field trials and data collections	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5223410	28068921	XZ	PLoS52	conceived and designed the experiments|conducted field trials and data collections	conducted field trials and data collections	Performed the experiments	Investigation	YES
5223410	28068921	YC	PLoS52	conceived and designed the experiments|conducted field trials and data collections	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5223410	28068921	YC	PLoS52	conceived and designed the experiments|conducted field trials and data collections	conducted field trials and data collections	Performed the experiments	Investigation	YES
5223410	28068921	YL	PLoS52	conceived and designed the experiments|conducted field trials and data collections	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5223410	28068921	YL	PLoS52	conceived and designed the experiments|conducted field trials and data collections	conducted field trials and data collections	Performed the experiments	Investigation	YES
5223410	28068921	ZL	PLoS52	performed genotyping	performed genotyping	Performed the experiments	Investigation	YES
5223410	28068921	ZX	PLoS52	performed genotyping	performed genotyping	Performed the experiments	Investigation	YES
4615994	26493348	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4615994	26493348	MB	2	made substantial contribution to conception and design as well as in drafting the manuscript	made substantial contribution to conception and design as well as in drafting the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4615994	26493348	PG	2	was involved in drafting the manuscript and revising it critically for important intellectual content	was involved in drafting the manuscript and revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4615994	26493348	RH	2	carried out the research and prepared the manuscript	carried out the research and prepared the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4615994	26493348	SB	2	helped to draft the manuscript	helped to draft the manuscript	Wrote the paper	Writing - Original Draft	YES
4615994	26493348	UL	2	contributed significantly in the acquisition of data and provided guidance on the analysis	contributed significantly in the acquisition of data and provided guidance on the analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources|Supervision	YES
4509895	26198341	Carlos F. Caceres	2	wrote the first manuscript draft, coordinated and incorporated input from co-authors, and completed the manuscript	wrote the first manuscript draft, coordinated and incorporated input from co-authors, and completed the manuscript	Wrote the paper	Project administration|Writing - Original Draft	YES
4509895	26198341	OReilly	2	provided substantial comments to the earlier drafts	provided substantial comments to the earlier drafts	Wrote the paper	Writing - Original Draft	YES
4509895	26198341	Peter Godfrey-Fausset	2	provided key ideas for some of the main arguments presented in the paper	provided key ideas for some of the main arguments presented in the paper	Conceived and designed the experiments	Conceptualization	YES
4509895	26198341	Salif Sow	2	provided substantial comments to the earlier drafts	provided substantial comments to the earlier drafts	Wrote the paper	Writing - Original Draft	YES
5419360	28970378	All authors	2	listed contributed to the development, writing, and editing of the manuscript	listed contributed to the development, writing, and editing of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4960678	27462360	All authors	2	contributed to the development of the manuscript and its content|read and approved the final manuscript	contributed to the development of the manuscript and its content	Wrote the paper	Writing - Original Draft	YES
4960678	27462360	All authors	2	contributed to the development of the manuscript and its content|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4960678	27462360	MJM	2	conceived of the study|analysed access study data to identify eligible participants	conceived of the study	Conceived and designed the experiments	Conceptualization	YES
4960678	27462360	MJM	2	conceived of the study|analysed access study data to identify eligible participants	analysed access study data to identify eligible participants	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4960678	27462360	RM	2	contributed to the analysis and interpretation of the study data	contributed to the analysis and interpretation of the study data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
4960678	27462360	TK	2	conceived of the study	conceived of the study	Conceived and designed the experiments	Conceptualization	YES
4960678	27462360	WS	2	conceived of the study|conducted most of the qualitative interviews, and coded and analysed the interview data	conceived of the study	Conceived and designed the experiments	Conceptualization	YES
4960678	27462360	WS	2	conceived of the study|conducted most of the qualitative interviews, and coded and analysed the interview data	conducted most of the qualitative interviews, and coded and analysed the interview data	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
4724026	26900455	AG	7	Data analysis/interpretation, drafting article, critical revision, approval of article	Data analysis/interpretation, drafting article, critical revision, approval of article	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
4724026	26900455	AP	7	Data analysis/interpretation, critical revision, approval of article	Data analysis/interpretation, critical revision, approval of article	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4724026	26900455	ED	7	Data analysis/interpretation, critical revision, approval of article	Data analysis/interpretation, critical revision, approval of article	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4724026	26900455	JG	7	Data analysis/interpretation, critical revision, approval of article, statistics	Data analysis/interpretation, critical revision, approval of article, statistics	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4724026	26900455	LS	7	Data analysis/interpretation, critical revision, approval of article	Data analysis/interpretation, critical revision, approval of article	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4724026	26900455	SJ	7	Data analysis/interpretation, critical revision, approval of article, statistics	Data analysis/interpretation, critical revision, approval of article, statistics	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4724026	26900455	ST	7	Concept/design, data analysis/interpretation, drafting article, critical revision, approval of article	Concept/design, data analysis/interpretation, drafting article, critical revision, approval of article	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
4724026	26900455	TS	7	Data analysis/interpretation, critical revision, approval of article	Data analysis/interpretation, critical revision, approval of article	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4724026	26900455	VA	7	Data analysis/interpretation, drafting article, critical revision, approval of article	Data analysis/interpretation, drafting article, critical revision, approval of article	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
4724026	26900455	YT	7	Data analysis/interpretation, critical revision, approval of article	Data analysis/interpretation, critical revision, approval of article	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4404253	25893992	AY	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404253	25893992	AY	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404253	25893992	HA	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404253	25893992	HA	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404253	25893992	WW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404253	25893992	WW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404253	25893992	WW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404253	25893992	WW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404253	25893992	WW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5513917	28769939	All authors	2	designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
5513917	28769939	EM	2	conducted the experiments, data analysis, and wrote the manuscript	conducted the experiments, data analysis, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5513917	28769939	IL	2	advised on rna seq work	advised on rna seq work	Performed the experiments	Investigation	YES
5513917	28769939	SH	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5513917	28769939	SM-M	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5478204	28456423	C.L.	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5478204	28456423	C.T.	PLoS52	analysed the data|conceived and designed the experiments	analysed the data	Analyzed the data	Formal analysis	YES
5478204	28456423	C.T.	PLoS52	analysed the data|conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5478204	28456423	E.G.	PLoS52	analysed the data|conceived and designed the experiments|contributed materials and reagents|wrote the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
5478204	28456423	E.G.	PLoS52	analysed the data|conceived and designed the experiments|contributed materials and reagents|wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5478204	28456423	E.G.	PLoS52	analysed the data|conceived and designed the experiments|contributed materials and reagents|wrote the manuscript	contributed materials and reagents	Contributed reagents/materials/analysis tools	Resources	YES
5478204	28456423	E.G.	PLoS52	analysed the data|conceived and designed the experiments|contributed materials and reagents|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5478204	28456423	E.L.	PLoS52	analysed the data|conceived and designed the experiments|contributed materials and reagents|wrote the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
5478204	28456423	E.L.	PLoS52	analysed the data|conceived and designed the experiments|contributed materials and reagents|wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5478204	28456423	E.L.	PLoS52	analysed the data|conceived and designed the experiments|contributed materials and reagents|wrote the manuscript	contributed materials and reagents	Contributed reagents/materials/analysis tools	Resources	YES
5478204	28456423	E.L.	PLoS52	analysed the data|conceived and designed the experiments|contributed materials and reagents|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5478204	28456423	G.G.	PLoS52	performed the experiments|analysed the data|contributed materials and reagents	performed the experiments	Performed the experiments	Investigation	YES
5478204	28456423	G.G.	PLoS52	performed the experiments|analysed the data|contributed materials and reagents	analysed the data	Analyzed the data	Formal analysis	YES
5478204	28456423	G.G.	PLoS52	performed the experiments|analysed the data|contributed materials and reagents	contributed materials and reagents	Contributed reagents/materials/analysis tools	Resources	YES
5478204	28456423	G.M.	PLoS52	analysed the data|conceived and designed the experiments|contributed materials and reagents|wrote the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
5478204	28456423	G.M.	PLoS52	analysed the data|conceived and designed the experiments|contributed materials and reagents|wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5478204	28456423	G.M.	PLoS52	analysed the data|conceived and designed the experiments|contributed materials and reagents|wrote the manuscript	contributed materials and reagents	Contributed reagents/materials/analysis tools	Resources	YES
5478204	28456423	G.M.	PLoS52	analysed the data|conceived and designed the experiments|contributed materials and reagents|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5478204	28456423	J.D.	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5478204	28456423	L.L.T.	PLoS52	analysed the data|conceived and designed the experiments	analysed the data	Analyzed the data	Formal analysis	YES
5478204	28456423	L.L.T.	PLoS52	analysed the data|conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5478204	28456423	L.P.	PLoS52	analysed the data|conceived and designed the experiments|contributed materials and reagents	analysed the data	Analyzed the data	Formal analysis	YES
5478204	28456423	L.P.	PLoS52	analysed the data|conceived and designed the experiments|contributed materials and reagents	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5478204	28456423	L.P.	PLoS52	analysed the data|conceived and designed the experiments|contributed materials and reagents	contributed materials and reagents	Contributed reagents/materials/analysis tools	Resources	YES
5478204	28456423	P.A.	PLoS52	analysed the data|conceived and designed the experiments	analysed the data	Analyzed the data	Formal analysis	YES
5478204	28456423	P.A.	PLoS52	analysed the data|conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5478204	28456423	S.G.	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
4724036	26900461	J Kay	7	Study design, data collection, writing	Study design, data collection, writing	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology	YES
4724036	26900461	Melisa Selwyn Selvendran	7	Data collection	Data collection	Performed the experiments	Investigation	YES
4724036	26900461	Rajkumar Cheluvappa	7	Writing, rebuttal-framing, submission. Michael	Writing, rebuttal-framing, submission. Michael	Wrote the paper	-	YES
4724036	26900461	V Vazquez	7	Study design, data collection	Study design, data collection	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5478205	28499924	H.K.	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5478205	28499924	K.N.	2	provided general supports and gave conceptual advice	provided general supports and gave conceptual advice	Conceived and designed the experiments	Conceptualization	YES
5478205	28499924	M.A.	2	conceived and supervised the project, performed experiments, analyzed data, and wrote the manuscript	conceived and supervised the project, performed experiments, analyzed data, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Supervision|Writing - Original Draft	YES
5478205	28499924	R.M.	2	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5478205	28499924	T.M.	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5478205	28499924	Y.K.	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5513918	28769940	BG	PLoS52	conceived and designed the experiments|wrote and revised the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5513918	28769940	BG	PLoS52	conceived and designed the experiments|wrote and revised the manuscript	wrote and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5513918	28769940	CM	PLoS52	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5513918	28769940	CZ	PLoS52	performed the experiments|analyzed data|wrote and revised the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5513918	28769940	CZ	PLoS52	performed the experiments|analyzed data|wrote and revised the manuscript	analyzed data	Analyzed the data	Formal analysis	YES
5513918	28769940	CZ	PLoS52	performed the experiments|analyzed data|wrote and revised the manuscript	wrote and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5513918	28769940	DB	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5513918	28769940	GA	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5513918	28769940	HX	PLoS52	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5513918	28769940	JQ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5513918	28769940	JW	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5513918	28769940	MKP	PLoS52	conceived and designed the experiments|performed the experiments|analyzed data|wrote and revised the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5513918	28769940	MKP	PLoS52	conceived and designed the experiments|performed the experiments|analyzed data|wrote and revised the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5513918	28769940	MKP	PLoS52	conceived and designed the experiments|performed the experiments|analyzed data|wrote and revised the manuscript	analyzed data	Analyzed the data	Formal analysis	YES
5513918	28769940	MKP	PLoS52	conceived and designed the experiments|performed the experiments|analyzed data|wrote and revised the manuscript	wrote and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5513918	28769940	RKV	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5513918	28769940	SW	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5513918	28769940	XR	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5513918	28769940	XW	PLoS52	conceived and designed the experiments|wrote and revised the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5513918	28769940	XW	PLoS52	conceived and designed the experiments|wrote and revised the manuscript	wrote and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5419361	28970380	Greg Barton	2	advised on planning and developing the project and all authors contributed to the manuscript preparation	advised on planning and developing the project and all authors contributed to the manuscript preparation	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5419361	28970380	Mark Borthwick	2	advised on planning and developing the project and all authors contributed to the manuscript preparation	advised on planning and developing the project and all authors contributed to the manuscript preparation	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5419361	28970380	Richard S. Bourne	2	contributed to planning the project, data analysis and the manuscript preparation	contributed to planning the project, data analysis and the manuscript preparation	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Original Draft	YES
5419361	28970380	Ruth E. Warin	2	lead the project, designed the questionnaire, co-ordinated the epdg testing and validation, dissemination of the survey, analysed the data, and led the manuscript preparation	lead the project, designed the questionnaire, co-ordinated the epdg testing and validation, dissemination of the survey, analysed the data, and led the manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Project administration|Validation|Writing - Original Draft	YES
4509897	26198346	Judith Auerbach	2	led the writing process and wrote the first draft of the paper	led the writing process and wrote the first draft of the paper	Wrote the paper	Writing - Original Draft	YES
4509897	26198346	Trevor Hoppe	2	contributed significantly to the concepts and ideas in the text and to its further iterations	contributed significantly to the concepts and ideas in the text and to its further iterations	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5223412	28073353	M.E.R.	2	implemented and applied valor to simulation experiments and real data	implemented and applied valor to simulation experiments and real data	Performed the experiments	Formal analysis|Investigation	YES
5223412	28073353	MER	2	developed the valor algorithm	developed the valor algorithm	Contributed reagents/materials/analysis tools	Software	YES
4960900	27462361	All authors	2	helped to draft the manuscript|read and approved the final manuscript	helped to draft the manuscript	Wrote the paper	Writing - Original Draft	YES
4960900	27462361	All authors	2	helped to draft the manuscript|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4404254	25893775	ABT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404254	25893775	ABT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404254	25893775	ABT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404254	25893775	ABT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404254	25893775	ABT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404254	25893775	AS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404254	25893775	AS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404254	25893775	AS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404254	25893775	AS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404254	25893775	GK	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404254	25893775	H. Satoh	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404254	25893775	H. Satoh	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404254	25893775	H. Sudo	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4404254	25893775	MK	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404254	25893775	MO	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4404254	25893775	TS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404254	25893775	TS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404254	25893775	YK	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4735557	26909151	Jae Huh	2	helped with the designed the project and completed the data collection with the	helped with the designed the project and completed the data collection with the	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4735557	26909151	John Brennan	2	was the supervising consultant	was the supervising consultant	-	Supervision	YES
4735557	26909151	Neil Tiwari	2	helped with the designed the project and completed the data collection with the	helped with the designed the project and completed the data collection with the	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4735557	26909151	Ross Dolan	2	designed the project and completed the data collection with the	designed the project and completed the data collection with the	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4735557	26909151	Tom Sproat	2	helped with the designed the project and completed the data collection with the	helped with the designed the project and completed the data collection with the	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5419362	28970396	Patrick Dawodu	2	analysed the data and wrote the paper	analysed the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5419362	28970396	Paul Rutter	2	analysed the data and wrote the paper	analysed the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5478209	28566250	A.T.	2	designed experiments and wrote the manuscript	designed experiments and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5478209	28566250	O.F.X.A.	2	provided critical discussion and edited the manuscript	provided critical discussion and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5478209	28566250	S.K.	2	designed, and performed experiments	designed, and performed experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5478209	28566250	T.T.	2	designed, and performed experiments	designed, and performed experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5478209	28566250	Y.S.	2	prepared and provided animals	prepared and provided animals	-	-	NO
5513928	28769962	MBR	2	carried out the molecular biology experiments	carried out the molecular biology experiments	Performed the experiments	Investigation	YES
5513928	28769962	MP	2	participated in the design of the study	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
5513928	28769962	SL	2	participated in the design of the study|analyzed the rna seq data	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
5513928	28769962	SL	2	participated in the design of the study|analyzed the rna seq data	analyzed the rna seq data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5513928	28769962	WL	2	carried out the molecular biology experiments	carried out the molecular biology experiments	Performed the experiments	Investigation	YES
5513928	28769962	XLY	2	carried out the molecular biology experiments	carried out the molecular biology experiments	Performed the experiments	Investigation	YES
5513928	28769962	XY	2	analyzed the rna seq data	analyzed the rna seq data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5513928	28769962	ZC	2	carried out the molecular biology experiments	carried out the molecular biology experiments	Performed the experiments	Investigation	YES
4712181	26763505	AG	2	identified the hypotheses for the current study|carried out the literature review and drafted the main sections of the manuscript	identified the hypotheses for the current study	Performed the experiments	Investigation	YES
4712181	26763505	AG	2	identified the hypotheses for the current study|carried out the literature review and drafted the main sections of the manuscript	carried out the literature review and drafted the main sections of the manuscript	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
4712181	26763505	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4712181	26763505	Board Member	2	of psychosis australia trust	of psychosis australia trust	-	-	NO
4712181	26763505	DH	2	were involved in the design and planning of the studies on youth mental health	were involved in the design and planning of the studies on youth mental health	Conceived and designed the experiments	Methodology	YES
4712181	26763505	ES	2	were involved in the design and planning of the studies on youth mental health	were involved in the design and planning of the studies on youth mental health	Conceived and designed the experiments	Methodology	YES
4712181	26763505	IH	2	were involved in the design and planning of the studies on youth mental health|identified the hypotheses for the current study|is a commissioner in australias national mental health commission	were involved in the design and planning of the studies on youth mental health	Conceived and designed the experiments	Methodology	YES
4712181	26763505	IH	2	were involved in the design and planning of the studies on youth mental health|identified the hypotheses for the current study|is a commissioner in australias national mental health commission	identified the hypotheses for the current study	Performed the experiments	Investigation	YES
4712181	26763505	IH	2	were involved in the design and planning of the studies on youth mental health|identified the hypotheses for the current study|is a commissioner in australias national mental health commission	is a commissioner in australias national mental health commission	-	-	NO
4712181	26763505	JS	2	identified the hypotheses for the current study|undertook the statistical analyses and assisted in writing the preliminary draft	identified the hypotheses for the current study	Performed the experiments	Investigation	YES
4712181	26763505	JS	2	identified the hypotheses for the current study|undertook the statistical analyses and assisted in writing the preliminary draft	undertook the statistical analyses and assisted in writing the preliminary draft	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4712181	26763505	Medical Research Council	2	in australia|including for research on sleep and actigraphy	in australia	-	-	NO
4712181	26763505	Medical Research Council	2	in australia|including for research on sleep and actigraphy	including for research on sleep and actigraphy	Performed the experiments	Investigation	YES
4712181	26763505	Mind Centre	2	at the university of sydney	at the university of sydney	-	-	NO
4712181	26763505	SN	2	were involved in the design and planning of the studies on youth mental health	were involved in the design and planning of the studies on youth mental health	Conceived and designed the experiments	Methodology	YES
3565231	23400644	Joan E. Bechtold	7	design, surgery, manuscript comments, discussion	design, surgery, manuscript comments, discussion	Conceived and designed the experiments|Performed the experiments	Investigation	YES
3565231	23400644	Jorgen Baas	7	design, surgery, manuscript comments, discussion	design, surgery, manuscript comments, discussion	Conceived and designed the experiments|Performed the experiments	Investigation	YES
3565231	23400644	Kjeld Soballe	7	design, manuscript comments, discussion	design, manuscript comments, discussion	Conceived and designed the experiments	-	YES
3565231	23400644	Mette Sorensen	7	design, surgery, manuscript comments, discussion	design, surgery, manuscript comments, discussion	Conceived and designed the experiments|Performed the experiments	Investigation	YES
4509898	26198340	BLJ	2	conducted the analyses, and all authors contributed to the writing of the manuscript	conducted the analyses, and all authors contributed to the writing of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4509898	26198340	FM	2	conceived and designed the analysis	conceived and designed the analysis	Conceived and designed the experiments	Conceptualization	YES
4509898	26198340	IC	2	conceived and designed the analysis|conducted the analyses, and all authors contributed to the writing of the manuscript	conceived and designed the analysis	Conceived and designed the experiments	Conceptualization	YES
4509898	26198340	IC	2	conceived and designed the analysis|conducted the analyses, and all authors contributed to the writing of the manuscript	conducted the analyses, and all authors contributed to the writing of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4509898	26198340	KO	2	conceived and designed the analysis	conceived and designed the analysis	Conceived and designed the experiments	Conceptualization	YES
4509898	26198340	TBH	2	conceived and designed the analysis	conceived and designed the analysis	Conceived and designed the experiments	Conceptualization	YES
4404255	25893706	CR	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404255	25893706	CR	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404255	25893706	CR	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404255	25893706	DLG	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404255	25893706	DLG	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404255	25893706	DLG	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404255	25893706	H. Choi	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404255	25893706	H. Choi	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404255	25893706	H. Choi	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404255	25893706	H. Choi	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404255	25893706	H. Colman	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404255	25893706	H. Colman	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404255	25893706	H. Colman	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404255	25893706	JG	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404255	25893706	JG	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404255	25893706	JG	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404255	25893706	LEH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404255	25893706	LEH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404255	25893706	LEH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404255	25893706	LEH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404255	25893706	RLJ	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404255	25893706	RLJ	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404255	25893706	SB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404255	25893706	SB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404255	25893706	SB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404255	25893706	SC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404255	25893706	SC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404255	25893706	SC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5223433	28068898	GX	2	participated in the transcriptomic analysis	participated in the transcriptomic analysis	-	-	NO
5223433	28068898	HZ	2	designed the experiments and drafted the manuscript|participated in the transcriptomic analysis	designed the experiments and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5223433	28068898	HZ	2	designed the experiments and drafted the manuscript|participated in the transcriptomic analysis	participated in the transcriptomic analysis	-	-	NO
5223433	28068898	JZ	2	helped to draft the manuscript	helped to draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5223433	28068898	LJ	2	carried out the physiological and molecular studies	carried out the physiological and molecular studies	Performed the experiments	Investigation	YES
5223433	28068898	ML	2	designed the experiments and drafted the manuscript|carried out the physiological and molecular studies|performed the data analysis	designed the experiments and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5223433	28068898	ML	2	designed the experiments and drafted the manuscript|carried out the physiological and molecular studies|performed the data analysis	carried out the physiological and molecular studies	Performed the experiments	Investigation	YES
5223433	28068898	ML	2	designed the experiments and drafted the manuscript|carried out the physiological and molecular studies|performed the data analysis	performed the data analysis	Analyzed the data	Formal analysis	YES
5223433	28068898	NZ	2	carried out the physiological and molecular studies	carried out the physiological and molecular studies	Performed the experiments	Investigation	YES
5223433	28068898	PL	2	designed the experiments and drafted the manuscript	designed the experiments and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5223433	28068898	QC	2	designed the experiments and drafted the manuscript|carried out the physiological and molecular studies	designed the experiments and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5223433	28068898	QC	2	designed the experiments and drafted the manuscript|carried out the physiological and molecular studies	carried out the physiological and molecular studies	Performed the experiments	Investigation	YES
5223433	28068898	QZ	2	participated in the transcriptomic analysis	participated in the transcriptomic analysis	-	-	NO
5223433	28068898	RW	2	carried out the qrt-pcr validation	carried out the qrt-pcr validation	Performed the experiments	Investigation|Validation	YES
5223433	28068898	WT	2	performed the data analysis	performed the data analysis	Analyzed the data	Formal analysis	YES
5223433	28068898	XC	2	participated in the transcriptomic analysis	participated in the transcriptomic analysis	-	-	NO
5223433	28068898	ZZ	2	carried out the physiological and molecular studies|carried out the qrt-pcr validation	carried out the physiological and molecular studies	Performed the experiments	Investigation	YES
5223433	28068898	ZZ	2	carried out the physiological and molecular studies|carried out the qrt-pcr validation	carried out the qrt-pcr validation	Performed the experiments	Investigation|Validation	YES
4735571	26909150	AA	1	Concept	Concept	Conceived and designed the experiments	Conceptualization	YES
4735571	26909150	AM	1	Concept	Concept	Conceived and designed the experiments	Conceptualization	YES
4735571	26909150	All	1	Interpretation	Interpretation	Analyzed the data	Formal analysis	YES
4735571	26909150	All Data	1	Analysis	Analysis	-	-	NO
4735571	26909150	BK	1	Concept	Concept	Conceived and designed the experiments	Conceptualization	YES
4735571	26909150	JAS	1	Concept	Concept	Conceived and designed the experiments	Conceptualization	YES
5006584	27582777	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5006584	27582777	BNM	2	conceived and designed the study|participated in data collection|drafted the initial manuscript|compiled and analysed data|interpreted the analysis	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5006584	27582777	BNM	2	conceived and designed the study|participated in data collection|drafted the initial manuscript|compiled and analysed data|interpreted the analysis	participated in data collection	Performed the experiments	Investigation	YES
5006584	27582777	BNM	2	conceived and designed the study|participated in data collection|drafted the initial manuscript|compiled and analysed data|interpreted the analysis	drafted the initial manuscript	Wrote the paper	Writing - Original Draft	YES
5006584	27582777	BNM	2	conceived and designed the study|participated in data collection|drafted the initial manuscript|compiled and analysed data|interpreted the analysis	compiled and analysed data	Analyzed the data	Data curation|Formal analysis	YES
5006584	27582777	BNM	2	conceived and designed the study|participated in data collection|drafted the initial manuscript|compiled and analysed data|interpreted the analysis	interpreted the analysis	Analyzed the data	Formal analysis	YES
5006584	27582777	IK	2	drafted the initial manuscript|compiled and analysed data|interpreted the analysis	drafted the initial manuscript	Wrote the paper	Writing - Original Draft	YES
5006584	27582777	IK	2	drafted the initial manuscript|compiled and analysed data|interpreted the analysis	compiled and analysed data	Analyzed the data	Data curation|Formal analysis	YES
5006584	27582777	IK	2	drafted the initial manuscript|compiled and analysed data|interpreted the analysis	interpreted the analysis	Analyzed the data	Formal analysis	YES
5006584	27582777	JW	2	participated in data collection|conducted the laboratory analyses	participated in data collection	Performed the experiments	Investigation	YES
5006584	27582777	JW	2	participated in data collection|conducted the laboratory analyses	conducted the laboratory analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5006584	27582777	PM	2	conceived and designed the study|drafted the initial manuscript|interpreted the analysis	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5006584	27582777	PM	2	conceived and designed the study|drafted the initial manuscript|interpreted the analysis	drafted the initial manuscript	Wrote the paper	Writing - Original Draft	YES
5006584	27582777	PM	2	conceived and designed the study|drafted the initial manuscript|interpreted the analysis	interpreted the analysis	Analyzed the data	Formal analysis	YES
5006584	27582777	Patrick Kazooba	2	participated in data collection	participated in data collection	Performed the experiments	Investigation	YES
5006584	27582777	Pontiano Kaleebu	2	conceived and designed the study|interpreted the analysis	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5006584	27582777	Pontiano Kaleebu	2	conceived and designed the study|interpreted the analysis	interpreted the analysis	Analyzed the data	Formal analysis	YES
5006584	27582777	TS	2	participated in data collection|drafted the initial manuscript|interpreted the analysis	participated in data collection	Performed the experiments	Investigation	YES
5006584	27582777	TS	2	participated in data collection|drafted the initial manuscript|interpreted the analysis	drafted the initial manuscript	Wrote the paper	Writing - Original Draft	YES
5006584	27582777	TS	2	participated in data collection|drafted the initial manuscript|interpreted the analysis	interpreted the analysis	Analyzed the data	Formal analysis	YES
5006584	27582777	all authors	2	contributed to revision of the manuscript	contributed to revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5419364	28970397	Christina R. Hansen	2	designed the search strategy|searched the literature and screened all the titles and abstracts retrieved|reviewed the included literature	designed the search strategy	Conceived and designed the experiments	-	YES
5419364	28970397	Christina R. Hansen	2	designed the search strategy|searched the literature and screened all the titles and abstracts retrieved|reviewed the included literature	searched the literature and screened all the titles and abstracts retrieved	Performed the experiments	Formal analysis|Investigation	YES
5419364	28970397	Christina R. Hansen	2	designed the search strategy|searched the literature and screened all the titles and abstracts retrieved|reviewed the included literature	reviewed the included literature	-	Formal analysis	YES
5419364	28970397	Colin P. Bradley	2	reviewed the included literature|reviewed and gave their feedback	reviewed the included literature	-	Formal analysis	YES
5419364	28970397	Colin P. Bradley	2	reviewed the included literature|reviewed and gave their feedback	reviewed and gave their feedback	-	-	NO
5419364	28970397	Laura J. Sahm	2	designed the search strategy|reviewed the included literature|reviewed this|reviewed and gave their feedback	designed the search strategy	Conceived and designed the experiments	-	YES
5419364	28970397	Laura J. Sahm	2	designed the search strategy|reviewed the included literature|reviewed this|reviewed and gave their feedback	reviewed the included literature	-	Formal analysis	YES
5419364	28970397	Laura J. Sahm	2	designed the search strategy|reviewed the included literature|reviewed this|reviewed and gave their feedback	reviewed this	-	-	NO
5419364	28970397	Laura J. Sahm	2	designed the search strategy|reviewed the included literature|reviewed this|reviewed and gave their feedback	reviewed and gave their feedback	-	-	NO
4468285	26137489	Fernando Seoane	2	decided on the contents and the structure of the paper	decided on the contents and the structure of the paper	-	-	NO
4468285	26137489	Leigh C. Ward	2	decided on the contents and the structure of the paper	decided on the contents and the structure of the paper	-	-	NO
4509899	26198342	DC	2	researched and wrote the introduction, and coordinated the final draft of the manuscript	researched and wrote the introduction, and coordinated the final draft of the manuscript	Wrote the paper	Project administration|Writing - Original Draft	YES
4509899	26198342	FvG	2	researched and wrote the introduction, and coordinated the final draft of the manuscript	researched and wrote the introduction, and coordinated the final draft of the manuscript	Wrote the paper	Project administration|Writing - Original Draft	YES
5478242	28549777	D.K.	2	designed the study|wrote the manuscript|made review and supervised all experiments	designed the study	Conceived and designed the experiments	Methodology	YES
5478242	28549777	D.K.	2	designed the study|wrote the manuscript|made review and supervised all experiments	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5478242	28549777	D.K.	2	designed the study|wrote the manuscript|made review and supervised all experiments	made review and supervised all experiments	-	Supervision	YES
5478242	28549777	D.S.	2	carried out experiments	carried out experiments	Performed the experiments	Investigation	YES
5478242	28549777	K.G.	2	carried out experiments|wrote the manuscript|wrote the manuscript	carried out experiments	Performed the experiments	Investigation	YES
5478242	28549777	K.G.	2	carried out experiments|wrote the manuscript|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5478242	28549777	K.G.	2	carried out experiments|wrote the manuscript|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5478242	28549777	K.I.	2	carried out experiments	carried out experiments	Performed the experiments	Investigation	YES
5478242	28549777	K.S.	2	carried out experiments|wrote the manuscript	carried out experiments	Performed the experiments	Investigation	YES
5478242	28549777	K.S.	2	carried out experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5478242	28549777	M.Y.	2	carried out experiments	carried out experiments	Performed the experiments	Investigation	YES
5478242	28549777	S.M.	2	carried out experiments	carried out experiments	Performed the experiments	Investigation	YES
5478242	28549777	T.U.	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5513933	28769961	C-MJ	2	conducted parts of the experiments	conducted parts of the experiments	Performed the experiments	Investigation	YES
5513933	28769961	H-XH	2	conducted parts of the experiments	conducted parts of the experiments	Performed the experiments	Investigation	YES
5513933	28769961	M-JL	2	performed most of the experiments|analyzed and prepared the data	performed most of the experiments	Performed the experiments	Investigation	YES
5513933	28769961	M-JL	2	performed most of the experiments|analyzed and prepared the data	analyzed and prepared the data	Analyzed the data	Formal analysis	YES
5513933	28769961	MK	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5513933	28769961	S-SK	2	designed the experiments|conducted parts of the experiments|analyzed and prepared the data|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5513933	28769961	S-SK	2	designed the experiments|conducted parts of the experiments|analyzed and prepared the data|wrote the manuscript	conducted parts of the experiments	Performed the experiments	Investigation	YES
5513933	28769961	S-SK	2	designed the experiments|conducted parts of the experiments|analyzed and prepared the data|wrote the manuscript	analyzed and prepared the data	Analyzed the data	Formal analysis	YES
5513933	28769961	S-SK	2	designed the experiments|conducted parts of the experiments|analyzed and prepared the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5513933	28769961	T-KC	2	conducted parts of the experiments	conducted parts of the experiments	Performed the experiments	Investigation	YES
5513933	28769961	T-TY	2	conducted parts of the experiments	conducted parts of the experiments	Performed the experiments	Investigation	YES
5513933	28769961	Y-JL	2	conducted parts of the experiments	conducted parts of the experiments	Performed the experiments	Investigation	YES
4712184	26763504	All authors	2	have contributed to and have approved the final manuscript	have contributed to and have approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4712184	26763504	BE	2	wrote the initial draft	wrote the initial draft	Wrote the paper	Writing - Original Draft	YES
4712184	26763504	CH	2	contributed to bibliographic searches and drafting of the final manuscript	contributed to bibliographic searches and drafting of the final manuscript	Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
4712184	26763504	FB	2	contributed to bibliographic searches and drafting of the final manuscript	contributed to bibliographic searches and drafting of the final manuscript	Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
4712184	26763504	IM	2	contributed to bibliographic searches and drafting of the final manuscript	contributed to bibliographic searches and drafting of the final manuscript	Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
4712184	26763504	MA	2	wrote the initial draft	wrote the initial draft	Wrote the paper	Writing - Original Draft	YES
4712184	26763504	OAA	2	contributed to bibliographic searches and drafting of the final manuscript	contributed to bibliographic searches and drafting of the final manuscript	Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
6396143	30767519	J.W.	2	contributed equally	contributed equally	-	-	NO
6396143	30767519	K.E.D.	2	contributed equally	contributed equally	-	-	NO
4404257	25893827	AW	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4404257	25893827	AW	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4404257	25893827	CYL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404257	25893827	CYL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404257	25893827	CYL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404257	25893827	CYL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404257	25893827	CYL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404257	25893827	CZW	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4404257	25893827	CZW	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4404257	25893827	LN	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404257	25893827	LN	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404257	25893827	WW	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4404257	25893827	WW	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4404257	25893827	ZH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404257	25893827	ZH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404257	25893827	ZH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404257	25893827	ZH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404257	25893827	ZH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4509900	26198343	CH	2	suggested a framework for the manuscript|wrote sections of the manuscript|compiled the final draft	suggested a framework for the manuscript	-	-	NO
4509900	26198343	CH	2	suggested a framework for the manuscript|wrote sections of the manuscript|compiled the final draft	wrote sections of the manuscript	Wrote the paper	Writing - Original Draft	YES
4509900	26198343	CH	2	suggested a framework for the manuscript|wrote sections of the manuscript|compiled the final draft	compiled the final draft	Wrote the paper	Writing - Original Draft	YES
4509900	26198343	MW	2	wrote sections of the manuscript	wrote sections of the manuscript	Wrote the paper	Writing - Original Draft	YES
4509900	26198343	RM	2	wrote sections of the manuscript	wrote sections of the manuscript	Wrote the paper	Writing - Original Draft	YES
5223533	28068923	KG	PLoS52	conceived the project|designed and completed the experiments	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5223533	28068923	KG	PLoS52	conceived the project|designed and completed the experiments	designed and completed the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5223533	28068923	LP	PLoS52	wrote the manuscript|co-supervised the project	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5223533	28068923	LP	PLoS52	wrote the manuscript|co-supervised the project	co-supervised the project	-	Supervision	YES
5223533	28068923	PC	PLoS52	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5223533	28068923	SP	PLoS52	designed and completed the experiments|wrote the manuscript|co-supervised the project	designed and completed the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5223533	28068923	SP	PLoS52	designed and completed the experiments|wrote the manuscript|co-supervised the project	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5223533	28068923	SP	PLoS52	designed and completed the experiments|wrote the manuscript|co-supervised the project	co-supervised the project	-	Supervision	YES
5223533	28068923	XL	PLoS52	conceived the project|designed and completed the experiments|analyzed the data|wrote the manuscript	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5223533	28068923	XL	PLoS52	conceived the project|designed and completed the experiments|analyzed the data|wrote the manuscript	designed and completed the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5223533	28068923	XL	PLoS52	conceived the project|designed and completed the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5223533	28068923	XL	PLoS52	conceived the project|designed and completed the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4739148	26870324	All authors	2	contributed to and approve of the final version of this manuscript	contributed to and approve of the final version of this manuscript	-	-	NO
5419365	28970400	Agnieska Skowron	2	helped with the distribution of the survey	helped with the distribution of the survey	Performed the experiments	Investigation	YES
5419365	28970400	All authors	2	provided useful criticism and suggestions during revision of the manuscript	provided useful criticism and suggestions during revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5419365	28970400	Annie Marcincal	2	helped with the distribution of the survey	helped with the distribution of the survey	Performed the experiments	Investigation	YES
5419365	28970400	Antonio Sanchez Pozo	2	developed the questionnaire|helped with the distribution of the survey	developed the questionnaire	-	-	NO
5419365	28970400	Antonio Sanchez Pozo	2	developed the questionnaire|helped with the distribution of the survey	helped with the distribution of the survey	Performed the experiments	Investigation	YES
5419365	28970400	Borut Bozic	2	helped with the distribution of the survey	helped with the distribution of the survey	Performed the experiments	Investigation	YES
5419365	28970400	Chris van Schravendijk	2	assured the contacts with medine2	assured the contacts with medine2	-	-	NO
5419365	28970400	Constantin Mircioiu	2	played a major role in the statistical analyses of the data	played a major role in the statistical analyses of the data	Analyzed the data	Formal analysis	YES
5419365	28970400	Dimitrios Rekkas	2	developed the questionnaire|helped with the distribution of the survey	developed the questionnaire	-	-	NO
5419365	28970400	Dimitrios Rekkas	2	developed the questionnaire|helped with the distribution of the survey	helped with the distribution of the survey	Performed the experiments	Investigation	YES
5419365	28970400	Jeffrey Atkinson	2	designed, constructed, ran and analysed the survey and wrote the paper	designed, constructed, ran and analysed the survey and wrote the paper	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5419365	28970400	Jouni Hirvonen	2	helped with the distribution of the survey	helped with the distribution of the survey	Performed the experiments	Investigation	YES
5419365	28970400	Kristien De Paepe	2	ran the phar-qa consortium	ran the phar-qa consortium	Performed the experiments	Investigation	YES
5513936	28769936	FVS	2	the corresponding author of the manuscript	the corresponding author of the manuscript	-	-	NO
5513936	28769936	SHJ	2	design of the work, analysis, drafting the work or revising it critically for important intellectual content, final approval of the version to be published	design of the work, analysis, drafting the work or revising it critically for important intellectual content, final approval of the version to be published	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5016933	27617023	Addis Intercontinental College	2	university of gondar in facilitating this study	university of gondar in facilitating this study	-	-	NO
5016933	27617023	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5016933	27617023	BT	2	did the statistical analysis again, the write up and preparation of the manuscript for publication	did the statistical analysis again, the write up and preparation of the manuscript for publication	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5016933	27617023	TB	2	contributed in data analysis, manuscript preparation and edited the final manuscript	contributed in data analysis, manuscript preparation and edited the final manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5016933	27617023	WW	2	advised during proposal writing and final manuscript preparation	advised during proposal writing and final manuscript preparation	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5514378	28596132	JB	CRediT	Study design|Data collection|Manuscript writing, original draft|Writing - review & editing	Study design	Conceived and designed the experiments	Methodology	YES
5514378	28596132	JB	CRediT	Study design|Data collection|Manuscript writing, original draft|Writing - review & editing	Data collection	Performed the experiments	Investigation	YES
5514378	28596132	JB	CRediT	Study design|Data collection|Manuscript writing, original draft|Writing - review & editing	Manuscript writing, original draft	Wrote the paper	Writing - Original Draft	YES
5514378	28596132	JB	CRediT	Study design|Data collection|Manuscript writing, original draft|Writing - review & editing	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
5514378	28596132	MHK	CRediT	Study design|Data collection|Data analysis|Data interpretation|Manuscript writing, original draft|Writing - review & editing	Study design	Conceived and designed the experiments	Methodology	YES
5514378	28596132	MHK	CRediT	Study design|Data collection|Data analysis|Data interpretation|Manuscript writing, original draft|Writing - review & editing	Data collection	Performed the experiments	Investigation	YES
5514378	28596132	MHK	CRediT	Study design|Data collection|Data analysis|Data interpretation|Manuscript writing, original draft|Writing - review & editing	Data analysis	Analyzed the data	Formal analysis	YES
5514378	28596132	MHK	CRediT	Study design|Data collection|Data analysis|Data interpretation|Manuscript writing, original draft|Writing - review & editing	Data interpretation	Analyzed the data	Formal analysis	YES
5514378	28596132	MHK	CRediT	Study design|Data collection|Data analysis|Data interpretation|Manuscript writing, original draft|Writing - review & editing	Manuscript writing, original draft	Wrote the paper	Writing - Original Draft	YES
5514378	28596132	MHK	CRediT	Study design|Data collection|Data analysis|Data interpretation|Manuscript writing, original draft|Writing - review & editing	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
5514378	28596132	SYC	CRediT	Study design|Data collection|Literature search	Study design	Conceived and designed the experiments	Methodology	YES
5514378	28596132	SYC	CRediT	Study design|Data collection|Literature search	Data collection	Performed the experiments	Investigation	YES
5514378	28596132	SYC	CRediT	Study design|Data collection|Literature search	Literature search	-	Formal analysis	YES
5514378	28596132	VS	CRediT	Data analysis|Data interpretation|Writing - review & editing	Data analysis	Analyzed the data	Formal analysis	YES
5514378	28596132	VS	CRediT	Data analysis|Data interpretation|Writing - review & editing	Data interpretation	Analyzed the data	Formal analysis	YES
5514378	28596132	VS	CRediT	Data analysis|Data interpretation|Writing - review & editing	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
4404259	25893964	AT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404259	25893964	AT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404259	25893964	AT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404259	25893964	AT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404259	25893964	AT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404259	25893964	EZ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404259	25893964	EZ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404259	25893964	EZ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404259	25893964	JF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404259	25893964	JF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404259	25893964	JF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404259	25893964	JF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404259	25893964	JF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404259	25893964	JV	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Designed the software used in analysis	Performed the experiments	Performed the experiments	Investigation	YES
4404259	25893964	JV	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Designed the software used in analysis	Analyzed the data	Analyzed the data	Formal analysis	YES
4404259	25893964	JV	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Designed the software used in analysis	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404259	25893964	JV	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Designed the software used in analysis	Designed the software used in analysis	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
4404259	25893964	LC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404259	25893964	LC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404259	25893964	LC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404259	25893964	RZ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404259	25893964	TJ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404259	25893964	TJ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404259	25893964	TJ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404259	25893964	TJ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404259	25893964	TO	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4404259	25893964	TO	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4509901	26198348	All authors	2	contributed to revisions and approved the final version of the report	contributed to revisions and approved the final version of the report	Wrote the paper	Writing - Review & Editing	YES
4509901	26198348	CC	2	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4509901	26198348	JMB	2	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4509901	26198348	MS	2	wrote the first draft of the report	wrote the first draft of the report	Wrote the paper	Writing - Original Draft	YES
4509901	26198348	RH	2	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4509901	26198348	RVB	2	conceived and designed the study|wrote the first draft of the report	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4509901	26198348	RVB	2	conceived and designed the study|wrote the first draft of the report	wrote the first draft of the report	Wrote the paper	Writing - Original Draft	YES
4509901	26198348	RY	2	collected the cost data	collected the cost data	Performed the experiments	Investigation	YES
5513964	28769953	AR	2	conceived and designed the study|managed the experimental plants, reared insects, conducted feeding tests, and prepared samples for hplc|conducted statistical analysis and wrote the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5513964	28769953	AR	2	conceived and designed the study|managed the experimental plants, reared insects, conducted feeding tests, and prepared samples for hplc|conducted statistical analysis and wrote the manuscript	managed the experimental plants, reared insects, conducted feeding tests, and prepared samples for hplc	Performed the experiments	Investigation	YES
5513964	28769953	AR	2	conceived and designed the study|managed the experimental plants, reared insects, conducted feeding tests, and prepared samples for hplc|conducted statistical analysis and wrote the manuscript	conducted statistical analysis and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5513964	28769953	HK	2	conducted the hplc analysis	conducted the hplc analysis	Performed the experiments	Investigation	YES
5513964	28769953	I-SN	2	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5513964	28769953	J-IP	2	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5513964	28769953	MH	2	conducted statistical analysis and wrote the manuscript	conducted statistical analysis and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4759523	26949530	Ana Monteiro	7	data collection	data collection	Performed the experiments	Investigation	YES
4759523	26949530	Antonio Oliveria	7	revision of the manuscript	revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4759523	26949530	Herculano Moreira	7	writing and revision	writing and revision	Wrote the paper	Writing - Review & Editing	YES
4759523	26949530	Joao Gaspar	7	revision of the manuscript	revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4759523	26949530	Nadia Tenreiro	7	study design, data collection and writing	study design, data collection and writing	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology	YES
4759523	26949530	Rita Marques	7	data collection	data collection	Performed the experiments	Investigation	YES
4759523	26949530	Silvia Silva	7	data collection	data collection	Performed the experiments	Investigation	YES
5223570	28068920	QD	2	performed the experiment	performed the experiment	Performed the experiments	Investigation	YES
5223570	28068920	ST	2	planned and designed the research	planned and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5223570	28068920	SZ	2	performed the experiment|revised the manuscript, and submitted the data to database	performed the experiment	Performed the experiments	Investigation	YES
5223570	28068920	SZ	2	performed the experiment|revised the manuscript, and submitted the data to database	revised the manuscript, and submitted the data to database	Contributed reagents/materials/analysis tools|Wrote the paper	Software|Writing - Review & Editing	YES
5223570	28068920	TL	2	analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5223570	28068920	ZT	2	prepared the reagents of experiments	prepared the reagents of experiments	Contributed reagents/materials/analysis tools	Resources	YES
5514379	28330601	BC	2	contributed individual parts and data	contributed individual parts and data	Contributed reagents/materials/analysis tools	Resources	YES
5514379	28330601	SM	2	contributed individual parts and data	contributed individual parts and data	Contributed reagents/materials/analysis tools	Resources	YES
5514379	28330601	TvZ	2	designed the review|wrote the review with input from all authors	designed the review	Conceived and designed the experiments	-	YES
5514379	28330601	TvZ	2	designed the review|wrote the review with input from all authors	wrote the review with input from all authors	Wrote the paper	Writing - Original Draft	YES
5514379	28330601	VIK	2	designed the review	designed the review	Conceived and designed the experiments	-	YES
4511823	26202669	BL	5	drafted the manuscript and developed the key components for methadone and ART integration	drafted the manuscript and developed the key components for methadone and ART integration	Wrote the paper	Writing - Original Draft	YES
4511823	26202669	DB	5	provided writing support with specific expertise in clinical care for PWID	provided writing support with specific expertise in clinical care for PWID	Wrote the paper	-	YES
4511823	26202669	JM	5	provided writing support with specific expertise in methadone and HIV treatment in Tanzania	provided writing support with specific expertise in methadone and HIV treatment in Tanzania	Wrote the paper	-	YES
4511823	26202669	RJ	5	provided writing support with specific expertise in methadone and HIV treatment in Tanzania	provided writing support with specific expertise in methadone and HIV treatment in Tanzania	Wrote the paper	-	YES
4404260	25894323	EP	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404260	25894323	EP	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404260	25894323	IG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404260	25894323	IG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404260	25894323	IG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404260	25894323	IG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404260	25894323	MK	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4404260	25894323	PJ	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4404260	25894323	PJ	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404260	25894323	TS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4404260	25894323	TS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4404260	25894323	WK	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5419366	28970399	Arijana Mestrovic	2	provided useful criticism and suggestions during revisions of the manuscript	provided useful criticism and suggestions during revisions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5419366	28970399	Ieva Stupans	2	conceived the work|played a major part in the writing of the manuscript	conceived the work	Conceived and designed the experiments	Conceptualization	YES
5419366	28970399	Ieva Stupans	2	conceived the work|played a major part in the writing of the manuscript	played a major part in the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5419366	28970399	Jeffrey Atkinson	2	conceived the work|played a major part in the writing of the manuscript|provided useful criticism and suggestions during revisions of the manuscript	conceived the work	Conceived and designed the experiments	Conceptualization	YES
5419366	28970399	Jeffrey Atkinson	2	conceived the work|played a major part in the writing of the manuscript|provided useful criticism and suggestions during revisions of the manuscript	played a major part in the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5419366	28970399	Jeffrey Atkinson	2	conceived the work|played a major part in the writing of the manuscript|provided useful criticism and suggestions during revisions of the manuscript	provided useful criticism and suggestions during revisions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5419366	28970399	Michael J. Rouse	2	played a major part in the writing of the manuscript|provided useful criticism and suggestions during revisions of the manuscript	played a major part in the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5419366	28970399	Michael J. Rouse	2	played a major part in the writing of the manuscript|provided useful criticism and suggestions during revisions of the manuscript	provided useful criticism and suggestions during revisions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5419366	28970399	Rose Nash	2	provided useful criticism and suggestions during revisions of the manuscript	provided useful criticism and suggestions during revisions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5016965	27617024	BL	PLoS5	Studies search	Studies search	-	-	NO
5016965	27617024	HC	PLoS5	Data extraction	Data extraction	Analyzed the data	Data curation	YES
5016965	27617024	HL	PLoS5	Conceived and designed the study	Conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5016965	27617024	JH	PLoS5	Studies search	Studies search	-	-	NO
5016965	27617024	JJ	PLoS5	Analyzed the data|Data extraction|Manuscript writing	Analyzed the data	Analyzed the data	Formal analysis	YES
5016965	27617024	JJ	PLoS5	Analyzed the data|Data extraction|Manuscript writing	Data extraction	Analyzed the data	Data curation	YES
5016965	27617024	JJ	PLoS5	Analyzed the data|Data extraction|Manuscript writing	Manuscript writing	Wrote the paper	Writing - Original Draft	YES
5016965	27617024	JS	PLoS5	Studies search	Studies search	-	-	NO
5016965	27617024	LY	PLoS5	Conceived and designed the study	Conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5016965	27617024	NZ	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5016965	27617024	WG	PLoS5	Analyzed the data|Studies search	Analyzed the data	Analyzed the data	Formal analysis	YES
5016965	27617024	WG	PLoS5	Analyzed the data|Studies search	Studies search	-	-	NO
5016965	27617024	XX	PLoS5	Analyzed the data|Data extraction|Manuscript writing	Analyzed the data	Analyzed the data	Formal analysis	YES
5016965	27617024	XX	PLoS5	Analyzed the data|Data extraction|Manuscript writing	Data extraction	Analyzed the data	Data curation	YES
5016965	27617024	XX	PLoS5	Analyzed the data|Data extraction|Manuscript writing	Manuscript writing	Wrote the paper	Writing - Original Draft	YES
5016965	27617024	YL	PLoS5	Data extraction	Data extraction	Analyzed the data	Data curation	YES
4469752	26146613	Ema Anastasiadou	2	designed and analyzed experiments and wrote the paper	designed and analyzed experiments and wrote the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4469752	26146613	Stefania Lymperi	2	contributed equally	contributed equally	-	-	NO
4469752	26146613	Vasiliki Taraslia	2	contributed equally	contributed equally	-	-	NO
5513965	28769955	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5513965	28769955	CP	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5513965	28769955	HL	PLoS52	performed gwas|analyzed the data	performed gwas	Performed the experiments	Investigation	YES
5513965	28769955	HL	PLoS52	performed gwas|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5513965	28769955	HW	PLoS52	conceived and designed the research	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5513965	28769955	HY	PLoS52	characterized the agronomic traits	characterized the agronomic traits	Performed the experiments	Investigation	YES
5513965	28769955	JL	PLoS52	characterized the agronomic traits	characterized the agronomic traits	Performed the experiments	Investigation	YES
5513965	28769955	JX	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5513965	28769955	MT	PLoS52	characterized the agronomic traits	characterized the agronomic traits	Performed the experiments	Investigation	YES
5513965	28769955	MZ	PLoS52	conceived and designed the research|analyzed the data|wrote the manuscript	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5513965	28769955	MZ	PLoS52	conceived and designed the research|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5513965	28769955	MZ	PLoS52	conceived and designed the research|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5513965	28769955	WH	PLoS52	conceived and designed the research	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5513965	28769955	XL	PLoS52	characterized the agronomic traits	characterized the agronomic traits	Performed the experiments	Investigation	YES
5513965	28769955	XS	PLoS52	characterized the agronomic traits	characterized the agronomic traits	Performed the experiments	Investigation	YES
5513965	28769955	XW	PLoS52	characterized the agronomic traits	characterized the agronomic traits	Performed the experiments	Investigation	YES
4761621	26955476	Ali Ugur Emre	1	Data collections	Data collections	Performed the experiments	Investigation	YES
4761621	26955476	Dilek Arpaci	1	Study design|Writing	Study design	Conceived and designed the experiments	Methodology	YES
4761621	26955476	Dilek Arpaci	1	Study design|Writing	Writing	Wrote the paper	-	YES
4761621	26955476	Fatih Kuzu	1	Data collections	Data collections	Performed the experiments	Investigation	YES
4761621	26955476	Guldeniz Karadeniz Cakmak	1	Data analysis	Data analysis	Analyzed the data	Formal analysis	YES
4761621	26955476	Sevil Uygun Ilikhan	1	Study design	Study design	Conceived and designed the experiments	Methodology	YES
4761621	26955476	Taner Bayraktaroglu	1	Data analysis	Data analysis	Analyzed the data	Formal analysis	YES
4761621	26955476	Tarik Elri	1	Imaging	Imaging	Analyzed the data	Visualization	YES
4404297	25894545	MOH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404297	25894545	MOH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404297	25894545	MOH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404297	25894545	MOH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404297	25894545	MOH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404297	25894545	NJM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404297	25894545	NJM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404297	25894545	NJM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5419367	28970395	Courtney Sheehan	2	study design, statistical analysis, manuscript preparation and revisions	study design, statistical analysis, manuscript preparation and revisions	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5419367	28970395	Meredith Howard	2	study design, data collection, manuscript preparation and revisions	study design, data collection, manuscript preparation and revisions	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5419367	28970395	Robert D. Warhurst	2	study design, manuscript revisions	study design, manuscript revisions	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5223582	28068919	BB	2	designed the experiments and analysed the data|drafted the manuscript	designed the experiments and analysed the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5223582	28068919	BB	2	designed the experiments and analysed the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5223582	28068919	BY	2	conducted the lab experiments	conducted the lab experiments	Performed the experiments	Investigation	YES
5223582	28068919	EC	2	conducted the lab experiments	conducted the lab experiments	Performed the experiments	Investigation	YES
5223582	28068919	GHY	2	designed the experiments and analysed the data|drafted the manuscript	designed the experiments and analysed the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5223582	28068919	GHY	2	designed the experiments and analysed the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5223582	28068919	LW	2	designed the experiments and analysed the data|conducted the lab experiments|drafted the manuscript	designed the experiments and analysed the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5223582	28068919	LW	2	designed the experiments and analysed the data|conducted the lab experiments|drafted the manuscript	conducted the lab experiments	Performed the experiments	Investigation	YES
5223582	28068919	LW	2	designed the experiments and analysed the data|conducted the lab experiments|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5223582	28068919	PL	2	conducted the lab experiments	conducted the lab experiments	Performed the experiments	Investigation	YES
5223582	28068919	SQH	2	conducted the lab experiments	conducted the lab experiments	Performed the experiments	Investigation	YES
5223582	28068919	ZYW	2	conducted the lab experiments	conducted the lab experiments	Performed the experiments	Investigation	YES
4751106	26869176	AB	2	observed the cases, coordinated the clinical workup, took care of patients treatment and follow-up, conceived the case reports and the review, and prepared the manuscript	observed the cases, coordinated the clinical workup, took care of patients treatment and follow-up, conceived the case reports and the review, and prepared the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Project administration|Writing - Original Draft|Writing - Review & Editing	YES
4751106	26869176	AL	2	coordinated the medical and endocrinological workup	coordinated the medical and endocrinological workup	-	Project administration	YES
4751106	26869176	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4751106	26869176	EM	2	reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
4751106	26869176	FT	2	contributed to the literature search and reviewed the manuscript	contributed to the literature search and reviewed the manuscript	Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4751106	26869176	GT	2	carried out and interpreted the neurological workup	carried out and interpreted the neurological workup	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4751106	26869176	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
4761626	26955475	Akbar Zubairi	7	study design, data collections, data analysis, manuscript writing	study design, data collections, data analysis, manuscript writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4761626	26955475	Shahryar Noordin	7	study design, manuscript review, Overall supervision	study design, manuscript review, Overall supervision	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Review & Editing	YES
5419368	28970412	Amy Werremeyer	PLoS52	conceived and designed the study|wrote the paper	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5419368	28970412	Amy Werremeyer	PLoS52	conceived and designed the study|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5419368	28970412	Elizabeth Skoy	PLoS52	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5419368	28970412	Gina Aalgaard Kelly	PLoS52	participated in the analysis of the data	participated in the analysis of the data	Analyzed the data	Formal analysis	YES
5034415	27688794	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5034415	27688794	EMF	2	contributed to the study design, analysed the data, drafted the manuscript, interpreted the results and wrote the manuscript	contributed to the study design, analysed the data, drafted the manuscript, interpreted the results and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Original Draft	YES
5034415	27688794	EW	2	contributed to the study design, data analysis, interpretation of results and to the critical revision of the manuscript	contributed to the study design, data analysis, interpretation of results and to the critical revision of the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Review & Editing	YES
5034415	27688794	HM	2	contributed to the study design, data analysis and critical revision of the manuscript	contributed to the study design, data analysis and critical revision of the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Review & Editing	YES
5034415	27688794	IR	2	contributed to the critical revision of the manuscript	contributed to the critical revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5034415	27688794	NS	2	contributed to data analysis, the interpretation of results and to the writing of the manuscript	contributed to data analysis, the interpretation of results and to the writing of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5034415	27688794	OD	2	contributed to the study design, data analysis and critical revision of the manuscript	contributed to the study design, data analysis and critical revision of the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Review & Editing	YES
5514407	28625519	AK	PLoS52	provided administrative, technical, or material support	provided administrative, technical, or material support	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Project administration|Resources	YES
5514407	28625519	AM	PLoS52	provided administrative, technical, or material support	provided administrative, technical, or material support	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Project administration|Resources	YES
5514407	28625519	AT	PLoS52	provided administrative, technical, or material support	provided administrative, technical, or material support	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Project administration|Resources	YES
5514407	28625519	All authors	PLoS52	reviewed the results and approved the final version of the manuscript	reviewed the results and approved the final version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5514407	28625519	HA	PLoS52	provided administrative, technical, or material support	provided administrative, technical, or material support	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Project administration|Resources	YES
5514407	28625519	HS	PLoS52	provided administrative, technical, or material support	provided administrative, technical, or material support	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Project administration|Resources	YES
5514407	28625519	KK	PLoS52	provided administrative, technical, or material support	provided administrative, technical, or material support	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Project administration|Resources	YES
5514407	28625519	KS	PLoS52	provided administrative, technical, or material support	provided administrative, technical, or material support	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Project administration|Resources	YES
5514407	28625519	MA	PLoS52	provided administrative, technical, or material support	provided administrative, technical, or material support	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Project administration|Resources	YES
5514407	28625519	MW	PLoS52	conceived and designed the experiments|developed methodology and performed the experiments|analyzed the data and wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5514407	28625519	MW	PLoS52	conceived and designed the experiments|developed methodology and performed the experiments|analyzed the data and wrote the manuscript	developed methodology and performed the experiments	Performed the experiments	Investigation|Methodology	YES
5514407	28625519	MW	PLoS52	conceived and designed the experiments|developed methodology and performed the experiments|analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5514407	28625519	MY	PLoS52	provided administrative, technical, or material support	provided administrative, technical, or material support	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Project administration|Resources	YES
5514407	28625519	OK	PLoS52	provided administrative, technical, or material support	provided administrative, technical, or material support	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Project administration|Resources	YES
5514407	28625519	SI	PLoS52	provided administrative, technical, or material support	provided administrative, technical, or material support	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Project administration|Resources	YES
5514407	28625519	ST	PLoS52	provided administrative, technical, or material support	provided administrative, technical, or material support	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Project administration|Resources	YES
5514407	28625519	TK	PLoS52	provided administrative, technical, or material support	provided administrative, technical, or material support	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Project administration|Resources	YES
5514407	28625519	TT	PLoS52	provided administrative, technical, or material support	provided administrative, technical, or material support	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Project administration|Resources	YES
5514407	28625519	YI	PLoS52	provided administrative, technical, or material support	provided administrative, technical, or material support	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Project administration|Resources	YES
5514407	28625519	YK	PLoS52	conceived and designed the experiments|analyzed the data and wrote the manuscript|provided administrative, technical, or material support	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5514407	28625519	YK	PLoS52	conceived and designed the experiments|analyzed the data and wrote the manuscript|provided administrative, technical, or material support	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5514407	28625519	YK	PLoS52	conceived and designed the experiments|analyzed the data and wrote the manuscript|provided administrative, technical, or material support	provided administrative, technical, or material support	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Project administration|Resources	YES
5514407	28625519	YT	PLoS52	provided administrative, technical, or material support	provided administrative, technical, or material support	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Project administration|Resources	YES
4404305	25893247	AKV	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404305	25893247	FAM	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404305	25893247	FAM	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404305	25893247	HMK	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404305	25893247	HMK	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404305	25893247	JAS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404305	25893247	JAS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404305	25893247	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404305	25893247	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404305	25893247	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404305	25893247	LJ	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404305	25893247	LJ	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404305	25893247	LZ	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404305	25893247	LZ	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404305	25893247	NRD	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404305	25893247	SH	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4404305	25893247	XL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404305	25893247	XL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404305	25893247	XL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404305	25893247	XL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404305	25893247	ZL	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404305	25893247	ZL	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5513967	28769959	All the authors	2	have read and approved the final manuscript	have read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5513967	28769959	BS	2	designed research experiment|conducted experiments|analyzed the data and prepared the manuscript	designed research experiment	Conceived and designed the experiments	Methodology	YES
5513967	28769959	BS	2	designed research experiment|conducted experiments|analyzed the data and prepared the manuscript	conducted experiments	Performed the experiments	Investigation	YES
5513967	28769959	BS	2	designed research experiment|conducted experiments|analyzed the data and prepared the manuscript	analyzed the data and prepared the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5513967	28769959	DS	2	conducted experiments|analyzed the data and prepared the manuscript	conducted experiments	Performed the experiments	Investigation	YES
5513967	28769959	DS	2	conducted experiments|analyzed the data and prepared the manuscript	analyzed the data and prepared the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5513967	28769959	PK	2	conceived the research|designed research experiment|conducted experiments|analyzed the data and prepared the manuscript	conceived the research	Conceived and designed the experiments	Conceptualization	YES
5513967	28769959	PK	2	conceived the research|designed research experiment|conducted experiments|analyzed the data and prepared the manuscript	designed research experiment	Conceived and designed the experiments	Methodology	YES
5513967	28769959	PK	2	conceived the research|designed research experiment|conducted experiments|analyzed the data and prepared the manuscript	conducted experiments	Performed the experiments	Investigation	YES
5513967	28769959	PK	2	conceived the research|designed research experiment|conducted experiments|analyzed the data and prepared the manuscript	analyzed the data and prepared the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5513967	28769959	TS	2	analyzed the data and prepared the manuscript	analyzed the data and prepared the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4469755	26146631	Marelign Tilahun	2	was investigator and was involved in proposal writing, designing, recruitment and training of supervisors and data collectors, analysis and write-up, and all stages of the project implementation|did most of the analysis and write-up of the paper	was investigator and was involved in proposal writing, designing, recruitment and training of supervisors and data collectors, analysis and write-up, and all stages of the project implementation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Supervision	YES
4469755	26146631	Marelign Tilahun	2	was investigator and was involved in proposal writing, designing, recruitment and training of supervisors and data collectors, analysis and write-up, and all stages of the project implementation|did most of the analysis and write-up of the paper	did most of the analysis and write-up of the paper	Wrote the paper	Writing - Original Draft	YES
4469755	26146631	Shikur Mohamed	2	contributed to the designing of the methodology, recruitment, and training of supervisors and data collectors and was involved in designing of project proposal, design of questionnaires, and supervision and was involved in the final approval of the paper	contributed to the designing of the methodology, recruitment, and training of supervisors and data collectors and was involved in designing of project proposal, design of questionnaires, and supervision and was involved in the final approval of the paper	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources|Supervision	YES
4761695	26955477	AH	2	analyzed and interpreted data and revised the manuscript critically	analyzed and interpreted data and revised the manuscript critically	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4761695	26955477	All authors	2	gave their final approval of the version to be published and agreed to be accountable for all aspects of the work	gave their final approval of the version to be published and agreed to be accountable for all aspects of the work	-	-	NO
4761695	26955477	DK	2	acquired data and drafted the manuscript	acquired data and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4761695	26955477	EG	2	analyzed and interpreted data and drafted the manuscript	analyzed and interpreted data and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4761695	26955477	HG	2	analyzed and interpreted data and revised the manuscript critically	analyzed and interpreted data and revised the manuscript critically	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4761695	26955477	JS	2	acquired data and drafted the manuscript	acquired data and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4761695	26955477	MR	2	analyzed and interpreted data and revised the manuscript critically	analyzed and interpreted data and revised the manuscript critically	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4761695	26955477	PP	2	designed the study, analyzed data and drafted the manuscript	designed the study, analyzed data and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4761695	26955477	RI	2	analyzed and interpreted data and revised the manuscript critically	analyzed and interpreted data and revised the manuscript critically	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4761695	26955477	SB	2	designed the study, analyzed data and drafted the manuscript	designed the study, analyzed data and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4673087	26073628	J.A.T.D.	PLoS52	designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
4673087	26073628	K.A.H.	PLoS52	performed the experiments|analysed and interpreted the data	performed the experiments	Performed the experiments	Investigation	YES
4673087	26073628	K.A.H.	PLoS52	performed the experiments|analysed and interpreted the data	analysed and interpreted the data	Analyzed the data	Formal analysis	YES
4673087	26073628	P.C.	PLoS52	performed the experiments|analysed and interpreted the data	performed the experiments	Performed the experiments	Investigation	YES
4673087	26073628	P.C.	PLoS52	performed the experiments|analysed and interpreted the data	analysed and interpreted the data	Analyzed the data	Formal analysis	YES
4673087	26073628	R.A.B.	PLoS52	performed the experiments|analysed and interpreted the data	performed the experiments	Performed the experiments	Investigation	YES
4673087	26073628	R.A.B.	PLoS52	performed the experiments|analysed and interpreted the data	analysed and interpreted the data	Analyzed the data	Formal analysis	YES
4673087	26073628	S.-A.D.	PLoS52	designed the research|analysed and interpreted the data	designed the research	Conceived and designed the experiments	Methodology	YES
4673087	26073628	S.-A.D.	PLoS52	designed the research|analysed and interpreted the data	analysed and interpreted the data	Analyzed the data	Formal analysis	YES
4673087	26073628	S.T.	PLoS52	designed the research|performed the experiments|analysed and interpreted the data|wrote the manuscript, and all authors revised the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
4673087	26073628	S.T.	PLoS52	designed the research|performed the experiments|analysed and interpreted the data|wrote the manuscript, and all authors revised the manuscript	performed the experiments	Performed the experiments	Investigation	YES
4673087	26073628	S.T.	PLoS52	designed the research|performed the experiments|analysed and interpreted the data|wrote the manuscript, and all authors revised the manuscript	analysed and interpreted the data	Analyzed the data	Formal analysis	YES
4673087	26073628	S.T.	PLoS52	designed the research|performed the experiments|analysed and interpreted the data|wrote the manuscript, and all authors revised the manuscript	wrote the manuscript, and all authors revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5225503	28077090	AAFG	2	designed the gbs experiments|performed the gbs data analysis|performed the genetic map analysis|performed the qtl mapping analysis|participated in the study design and integrated the analysis of results|edited and revised the manuscript	designed the gbs experiments	Conceived and designed the experiments	Methodology	YES
5225503	28077090	AAFG	2	designed the gbs experiments|performed the gbs data analysis|performed the genetic map analysis|performed the qtl mapping analysis|participated in the study design and integrated the analysis of results|edited and revised the manuscript	performed the gbs data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5225503	28077090	AAFG	2	designed the gbs experiments|performed the gbs data analysis|performed the genetic map analysis|performed the qtl mapping analysis|participated in the study design and integrated the analysis of results|edited and revised the manuscript	performed the genetic map analysis	Performed the experiments	Investigation	YES
5225503	28077090	AAFG	2	designed the gbs experiments|performed the gbs data analysis|performed the genetic map analysis|performed the qtl mapping analysis|participated in the study design and integrated the analysis of results|edited and revised the manuscript	performed the qtl mapping analysis	Performed the experiments	Investigation	YES
5225503	28077090	AAFG	2	designed the gbs experiments|performed the gbs data analysis|performed the genetic map analysis|performed the qtl mapping analysis|participated in the study design and integrated the analysis of results|edited and revised the manuscript	participated in the study design and integrated the analysis of results	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5225503	28077090	AAFG	2	designed the gbs experiments|performed the gbs data analysis|performed the genetic map analysis|performed the qtl mapping analysis|participated in the study design and integrated the analysis of results|edited and revised the manuscript	edited and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5225503	28077090	APS	2	provided the rna seq data|participated in the study design and integrated the analysis of results|edited and revised the manuscript	provided the rna seq data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5225503	28077090	APS	2	provided the rna seq data|participated in the study design and integrated the analysis of results|edited and revised the manuscript	participated in the study design and integrated the analysis of results	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5225503	28077090	APS	2	provided the rna seq data|participated in the study design and integrated the analysis of results|edited and revised the manuscript	edited and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5225503	28077090	CBCS	2	provided the rna seq data	provided the rna seq data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5225503	28077090	COA	2	performed the field experiment assessments and the phenotypic data analysis	performed the field experiment assessments and the phenotypic data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5225503	28077090	EAC	2	provided the rna seq data	provided the rna seq data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5225503	28077090	FZB	2	designed the gbs experiments	designed the gbs experiments	Conceived and designed the experiments	Methodology	YES
5225503	28077090	GRAM	2	designed the gbs experiments|performed the gbs data analysis|performed the genetic map analysis|participated in the study design and integrated the analysis of results|critically read the manuscript	designed the gbs experiments	Conceived and designed the experiments	Methodology	YES
5225503	28077090	GRAM	2	designed the gbs experiments|performed the gbs data analysis|performed the genetic map analysis|participated in the study design and integrated the analysis of results|critically read the manuscript	performed the gbs data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5225503	28077090	GRAM	2	designed the gbs experiments|performed the gbs data analysis|performed the genetic map analysis|participated in the study design and integrated the analysis of results|critically read the manuscript	performed the genetic map analysis	Performed the experiments	Investigation	YES
5225503	28077090	GRAM	2	designed the gbs experiments|performed the gbs data analysis|performed the genetic map analysis|participated in the study design and integrated the analysis of results|critically read the manuscript	participated in the study design and integrated the analysis of results	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5225503	28077090	GRAM	2	designed the gbs experiments|performed the gbs data analysis|performed the genetic map analysis|participated in the study design and integrated the analysis of results|critically read the manuscript	critically read the manuscript	-	-	NO
5225503	28077090	GSP	2	performed the field experiment assessments and the phenotypic data analysis|performed the gbs data analysis|performed the genetic map analysis|participated in the study design and integrated the analysis of results	performed the field experiment assessments and the phenotypic data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5225503	28077090	GSP	2	performed the field experiment assessments and the phenotypic data analysis|performed the gbs data analysis|performed the genetic map analysis|participated in the study design and integrated the analysis of results	performed the gbs data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5225503	28077090	GSP	2	performed the field experiment assessments and the phenotypic data analysis|performed the gbs data analysis|performed the genetic map analysis|participated in the study design and integrated the analysis of results	performed the genetic map analysis	Performed the experiments	Investigation	YES
5225503	28077090	GSP	2	performed the field experiment assessments and the phenotypic data analysis|performed the gbs data analysis|performed the genetic map analysis|participated in the study design and integrated the analysis of results	participated in the study design and integrated the analysis of results	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5225503	28077090	HPH	2	conceived and designed the field experiments	conceived and designed the field experiments	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
5225503	28077090	MCM	2	performed the field experiment assessments and the phenotypic data analysis	performed the field experiment assessments and the phenotypic data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5225503	28077090	MSC	2	conceived and designed the field experiments|designed the gbs experiments|participated in the study design and integrated the analysis of results|edited and revised the manuscript	conceived and designed the field experiments	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
5225503	28077090	MSC	2	conceived and designed the field experiments|designed the gbs experiments|participated in the study design and integrated the analysis of results|edited and revised the manuscript	designed the gbs experiments	Conceived and designed the experiments	Methodology	YES
5225503	28077090	MSC	2	conceived and designed the field experiments|designed the gbs experiments|participated in the study design and integrated the analysis of results|edited and revised the manuscript	participated in the study design and integrated the analysis of results	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5225503	28077090	MSC	2	conceived and designed the field experiments|designed the gbs experiments|participated in the study design and integrated the analysis of results|edited and revised the manuscript	edited and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5225503	28077090	RG	2	performed the qtl mapping analysis|critically read the manuscript	performed the qtl mapping analysis	Performed the experiments	Investigation	YES
5225503	28077090	RG	2	performed the qtl mapping analysis|critically read the manuscript	critically read the manuscript	-	-	NO
5225503	28077090	SSR	2	trap marker data generation	trap marker data generation	-	-	NO
5225503	28077090	TWAB	2	performed the field experiment assessments and the phenotypic data analysis|designed the gbs experiments|performed the genetic map analysis|participated in the study design and integrated the analysis of results	performed the field experiment assessments and the phenotypic data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5225503	28077090	TWAB	2	performed the field experiment assessments and the phenotypic data analysis|designed the gbs experiments|performed the genetic map analysis|participated in the study design and integrated the analysis of results	designed the gbs experiments	Conceived and designed the experiments	Methodology	YES
5225503	28077090	TWAB	2	performed the field experiment assessments and the phenotypic data analysis|designed the gbs experiments|performed the genetic map analysis|participated in the study design and integrated the analysis of results	performed the genetic map analysis	Performed the experiments	Investigation	YES
5225503	28077090	TWAB	2	performed the field experiment assessments and the phenotypic data analysis|designed the gbs experiments|performed the genetic map analysis|participated in the study design and integrated the analysis of results	participated in the study design and integrated the analysis of results	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5419369	28970401	Nilesh Patel	2	conceived and designed the research project|put together the manuscript for publication	conceived and designed the research project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5419369	28970401	Nilesh Patel	2	conceived and designed the research project|put together the manuscript for publication	put together the manuscript for publication	-	-	NO
5419369	28970401	Reem Kayyali	2	conceived and designed the research project	conceived and designed the research project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5419369	28970401	Shahmina Begum	2	performed the interviews and analysed the data	performed the interviews and analysed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3636484	23667406	APS	2	was involved in the initial idea, the test design and preparation of the manuscript	was involved in the initial idea, the test design and preparation of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
3636484	23667406	AS	2	prepared cadaver specimen and tested these	prepared cadaver specimen and tested these	Performed the experiments	Investigation	YES
3636484	23667406	All authors	2	were fully involved in the study and preparation of the manuscript	were fully involved in the study and preparation of the manuscript	Wrote the paper	Writing - Original Draft	YES
3636484	23667406	JK	2	designed the test device, wrote parts of the article and lead the cadaveric experiments	designed the test device, wrote parts of the article and lead the cadaveric experiments	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3636484	23667406	MH	2	build the devise and performed initial testing	build the devise and performed initial testing	Conceived and designed the experiments|Performed the experiments	Investigation	YES
3636484	23667406	RW	2	performed the technical parts of the device and statistical calculations	performed the technical parts of the device and statistical calculations	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4404307	25893989	ASR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404307	25893989	ASR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404307	25893989	ASR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404307	25893989	ASR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404307	25893989	CRJ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404307	25893989	GAS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404307	25893989	JPO	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404307	25893989	KLM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404307	25893989	TB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404307	25893989	TB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404307	25893989	TB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404307	25893989	TB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404307	25893989	TC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404307	25893989	TC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404307	25893989	TC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404307	25893989	TC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404307	25893989	YT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404307	25893989	YT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404307	25893989	YT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404307	25893989	YT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5513968	28769943	EDS	2	worked on the statistical analysis	worked on the statistical analysis	Performed the experiments|Analyzed the data	Formal analysis	YES
5513968	28769943	GG	2	made the gas exchange measurements and fluorescence analysis	made the gas exchange measurements and fluorescence analysis	Performed the experiments	Investigation	YES
5513968	28769943	GR	2	had the original idea on testing omeprazole on plants and contributed to data analysis	had the original idea on testing omeprazole on plants and contributed to data analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation	YES
5513968	28769943	MVO	2	wrote the paper and did most of the experimental work|coordinated the research work	wrote the paper and did most of the experimental work	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5513968	28769943	MVO	2	wrote the paper and did most of the experimental work|coordinated the research work	coordinated the research work	Performed the experiments	Investigation|Project administration	YES
5513968	28769943	PC	2	worked on ion analysis and contributed to writing	worked on ion analysis and contributed to writing	Performed the experiments|Wrote the paper	-	YES
5513968	28769943	PW	2	worked on ion analysis and contributed to writing	worked on ion analysis and contributed to writing	Performed the experiments|Wrote the paper	-	YES
5513968	28769943	SS	2	contributed to plant growth analyses and molecular characterization	contributed to plant growth analyses and molecular characterization	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5513968	28769943	VC	2	worked on the statistical analysis	worked on the statistical analysis	Performed the experiments|Analyzed the data	Formal analysis	YES
4771673	26928123	AS	2	contributed to drafting of the final manuscript	contributed to drafting of the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4771673	26928123	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4771673	26928123	DK	2	contributed to drafting of the final manuscript	contributed to drafting of the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4771673	26928123	HYS	2	contributed to drafting of the final manuscript	contributed to drafting of the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4771673	26928123	NOR	2	wrote the initial draft and conducted all statistical analyses	wrote the initial draft and conducted all statistical analyses	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4771673	26928123	SC	2	contributed to drafting of the final manuscript	contributed to drafting of the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5034514	27688793	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5034514	27688793	Medical Sciences	2	jimma university	jimma university	-	-	NO
5034514	27688793	NH	2	analyzed the data, interpreted the data, and revised it critically for important intellectual content	analyzed the data, interpreted the data, and revised it critically for important intellectual content	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5034514	27688793	SH	2	conceived and designed the study, acquired the data, analyzed and interpreted the data, and drafted the manuscript	conceived and designed the study, acquired the data, analyzed and interpreted the data, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5034514	27688793	TB	2	analyzed the data, interpreted the data, and revised it critically for important intellectual content	analyzed the data, interpreted the data, and revised it critically for important intellectual content	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5034514	27688793	The author	2	would like to express due appreciation for jimma university specialized hospital for allowing us to access patients data	would like to express due appreciation for jimma university specialized hospital for allowing us to access patients data	-	-	NO
5034514	27688793	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
4469756	26146620	Hongfei Duan	2	contributed equally to this work	contributed equally to this work	-	-	NO
4469756	26146620	Wenjuan Nie	2	contributed equally to this work	contributed equally to this work	-	-	NO
5419371	28970403	Katherine Montag Schafer	2	collected and compiled data	collected and compiled data	Performed the experiments	Data curation|Investigation	YES
5419371	28970403	The authors	2	jointly analyzed the data and wrote the paper	jointly analyzed the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5552210	28712768	A.S.	2	interpreted and analyzed data	interpreted and analyzed data	Analyzed the data	Formal analysis	YES
5552210	28712768	B.A.	2	interpreted and analyzed data	interpreted and analyzed data	Analyzed the data	Formal analysis	YES
5552210	28712768	B.S.	2	performed experiments, interpreted and analyzed data	performed experiments, interpreted and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5552210	28712768	C.M.	2	designed assays, interpreted and analyzed data and edited the manuscript	designed assays, interpreted and analyzed data and edited the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
5552210	28712768	O.L.	2	performed experiments, interpreted and analyzed data	performed experiments, interpreted and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5552210	28712768	P.D.	2	interpreted and analyzed data	interpreted and analyzed data	Analyzed the data	Formal analysis	YES
5552210	28712768	V.P.	2	performed statistical analysis	performed statistical analysis	Analyzed the data	Formal analysis	YES
5552210	28712768	V.V.	2	designed assays, interpreted and analyzed data, wrote and edited the manuscript	designed assays, interpreted and analyzed data, wrote and edited the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5513970	28769954	BD	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5513970	28769954	JG	2	designed the experiment|wrote the manuscript	designed the experiment	Conceived and designed the experiments	Methodology	YES
5513970	28769954	JG	2	designed the experiment|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5513970	28769954	JW	2	performed the experiments and analyzed the data|wrote the manuscript	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5513970	28769954	JW	2	performed the experiments and analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5513970	28769954	QM	2	designed the experiment|wrote the manuscript	designed the experiment	Conceived and designed the experiments	Methodology	YES
5513970	28769954	QM	2	designed the experiment|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5513970	28769954	QS	2	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5513970	28769954	TQ	2	performed the experiments and analyzed the data|wrote the manuscript	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5513970	28769954	TQ	2	performed the experiments and analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4792817	26980087	All authors	2	contributed to the final manuscript|read and approved the final manuscript	contributed to the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4792817	26980087	All authors	2	contributed to the final manuscript|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4792817	26980087	BF	2	made contributions to conception and design of the study, as well as acquisition of data|wrote the first draft of the manuscript	made contributions to conception and design of the study, as well as acquisition of data	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceptualization|Investigation|Methodology|Resources	YES
4792817	26980087	BF	2	made contributions to conception and design of the study, as well as acquisition of data|wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
4792817	26980087	DS	2	performed the statistical analyses and contributed to interpretation of the data	performed the statistical analyses and contributed to interpretation of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
4792817	26980087	LC	2	made contributions to conception and design of the study, as well as acquisition of data|performed the statistical analyses and contributed to interpretation of the data|wrote the first draft of the manuscript	made contributions to conception and design of the study, as well as acquisition of data	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceptualization|Investigation|Methodology|Resources	YES
4792817	26980087	LC	2	made contributions to conception and design of the study, as well as acquisition of data|performed the statistical analyses and contributed to interpretation of the data|wrote the first draft of the manuscript	performed the statistical analyses and contributed to interpretation of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
4792817	26980087	LC	2	made contributions to conception and design of the study, as well as acquisition of data|performed the statistical analyses and contributed to interpretation of the data|wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
4792817	26980087	LM	2	performed the statistical analyses and contributed to interpretation of the data	performed the statistical analyses and contributed to interpretation of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
4792817	26980087	RS	2	made contributions to conception and design of the study, as well as acquisition of data|wrote the first draft of the manuscript	made contributions to conception and design of the study, as well as acquisition of data	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceptualization|Investigation|Methodology|Resources	YES
4792817	26980087	RS	2	made contributions to conception and design of the study, as well as acquisition of data|wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
4404317	25894573	AT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404317	25894573	AT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404317	25894573	AT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404317	25894573	AT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404317	25894573	GG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404317	25894573	GG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404317	25894573	GG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404317	25894573	GG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404317	25894573	GG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404317	25894573	NBB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404317	25894573	NBB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4404317	25894573	NBB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4404317	25894573	NBB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404317	25894573	YS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404317	25894573	YS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4514899	26208630	JMB	2	was the principal author of the manuscript	was the principal author of the manuscript	Wrote the paper	Writing - Original Draft	YES
4773379	26958343	Guang Yim	2	collected substantial reconstructive data for the project	collected substantial reconstructive data for the project	Performed the experiments	Investigation	YES
4773379	26958343	James Hodson	2	provided statistical analysis	provided statistical analysis	Analyzed the data	Formal analysis	YES
4773379	26958343	Mark Foster	2	provided direction on study concept and helped on data collection	provided direction on study concept and helped on data collection	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceptualization|Investigation|Resources	YES
4773379	26958343	Phillipa Jackson	2	edited and wrote portions of the final draft	edited and wrote portions of the final draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4773379	26958343	Robert Staruch	2	wrote the first draft and edited all subsequent copies of the text	wrote the first draft and edited all subsequent copies of the text	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4773379	26958343	Steven Jeffery	2	provided direction and edited the final draft	provided direction and edited the final draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4773379	26958343	Tania Cubison	2	provided information and experience on surgical reconstruction which contributed substantially to the final draft of the paper	provided information and experience on surgical reconstruction which contributed substantially to the final draft of the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4518656	26221872	All authors	2	provided critical input to the manuscript and approved the final version	provided critical input to the manuscript and approved the final version	-	-	NO
4518656	26221872	GM	2	wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
5225507	28073340	CLS	2	assisted with the with the|helped with revisions	assisted with the with the	-	-	NO
5225507	28073340	CLS	2	assisted with the with the|helped with revisions	helped with revisions	Wrote the paper	Writing - Review & Editing	YES
5225507	28073340	EASB	2	performed all the laboratory experiments	performed all the laboratory experiments	Performed the experiments	Investigation	YES
5225507	28073340	KVX	2	performed all the laboratory experiments|did manual analysis and phylogenetics of specialized secondary metabolite genes and gene clusters, with the	performed all the laboratory experiments	Performed the experiments	Investigation	YES
5225507	28073340	KVX	2	performed all the laboratory experiments|did manual analysis and phylogenetics of specialized secondary metabolite genes and gene clusters, with the	did manual analysis and phylogenetics of specialized secondary metabolite genes and gene clusters, with the	Performed the experiments	Investigation	YES
5225507	28073340	LJV	2	conceived and managed the project and conducted manual confirmations of the data	conceived and managed the project and conducted manual confirmations of the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Data curation|Investigation|Project administration	YES
5225507	28073340	MFT	2	assisted with the with the|helped with revisions	assisted with the with the	-	-	NO
5225507	28073340	MFT	2	assisted with the with the|helped with revisions	helped with revisions	Wrote the paper	Writing - Review & Editing	YES
5225507	28073340	SSP	2	genes and characterization of the fungal protein families	genes and characterization of the fungal protein families	Performed the experiments	Investigation	YES
5552224	28754302	A.C.C.	2	conducted the statistical analyses	conducted the statistical analyses	Analyzed the data	Formal analysis	YES
5552224	28754302	All	2	contributed to interpreting the data|edited the manuscript and approved the final version of the manuscript for submission	contributed to interpreting the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5552224	28754302	All	2	contributed to interpreting the data|edited the manuscript and approved the final version of the manuscript for submission	edited the manuscript and approved the final version of the manuscript for submission	Wrote the paper	Writing - Review & Editing	YES
5552224	28754302	C.L.C.	2	conducted the statistical analyses	conducted the statistical analyses	Analyzed the data	Formal analysis	YES
5552224	28754302	C.S.P.	2	designed the study|prepared, stored and analyzed the samples|conducted the statistical analyses|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5552224	28754302	C.S.P.	2	designed the study|prepared, stored and analyzed the samples|conducted the statistical analyses|wrote the manuscript	prepared, stored and analyzed the samples	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5552224	28754302	C.S.P.	2	designed the study|prepared, stored and analyzed the samples|conducted the statistical analyses|wrote the manuscript	conducted the statistical analyses	Analyzed the data	Formal analysis	YES
5552224	28754302	C.S.P.	2	designed the study|prepared, stored and analyzed the samples|conducted the statistical analyses|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5552224	28754302	H.L.Y.	2	designed the study|conducted the frailty assessments|prepared, stored and analyzed the samples|conducted the statistical analyses|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5552224	28754302	H.L.Y.	2	designed the study|conducted the frailty assessments|prepared, stored and analyzed the samples|conducted the statistical analyses|wrote the manuscript	conducted the frailty assessments	Performed the experiments	Investigation	YES
5552224	28754302	H.L.Y.	2	designed the study|conducted the frailty assessments|prepared, stored and analyzed the samples|conducted the statistical analyses|wrote the manuscript	prepared, stored and analyzed the samples	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5552224	28754302	H.L.Y.	2	designed the study|conducted the frailty assessments|prepared, stored and analyzed the samples|conducted the statistical analyses|wrote the manuscript	conducted the statistical analyses	Analyzed the data	Formal analysis	YES
5552224	28754302	H.L.Y.	2	designed the study|conducted the frailty assessments|prepared, stored and analyzed the samples|conducted the statistical analyses|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5552224	28754302	J.F.H.	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5552224	28754302	J.M.W.	2	designed the study|prepared, stored and analyzed the samples	designed the study	Conceived and designed the experiments	Methodology	YES
5552224	28754302	J.M.W.	2	designed the study|prepared, stored and analyzed the samples	prepared, stored and analyzed the samples	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5552224	28754302	P.J.M.	2	designed the study|prepared, stored and analyzed the samples	designed the study	Conceived and designed the experiments	Methodology	YES
5552224	28754302	P.J.M.	2	designed the study|prepared, stored and analyzed the samples	prepared, stored and analyzed the samples	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5552224	28754302	S.M.C.	2	designed the study|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5552224	28754302	S.M.C.	2	designed the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5419372	28970411	Alfred Health	2	contributed to critical review of the manuscript	contributed to critical review of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5419372	28970411	Linda Graudins	2	developed and supervises the medication safety program for pharmacy interns and staff orientation and lectures for undergraduate students and medical interns and the writing of the manuscript	developed and supervises the medication safety program for pharmacy interns and staff orientation and lectures for undergraduate students and medical interns and the writing of the manuscript	Wrote the paper	Software|Supervision|Writing - Original Draft	YES
4776268	26981237	Javier Ramos-Jimenez	1	Medrano, study design, analysis and interpretation of the data	Medrano, study design, analysis and interpretation of the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
4792823	26928122	AL	2	participated in the original clinical trial study design and conduct, as well as the analysis of data used for the present secondary data analysis	participated in the original clinical trial study design and conduct, as well as the analysis of data used for the present secondary data analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
4792823	26928122	AP	2	participated in the original clinical trial study design and conduct, as well as the analysis of data used for the present secondary data analysis	participated in the original clinical trial study design and conduct, as well as the analysis of data used for the present secondary data analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
4792823	26928122	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4792823	26928122	EDB	2	participated in the study design, interpretation of statistical analyses, and manuscript preparation	participated in the study design, interpretation of statistical analyses, and manuscript preparation	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4792823	26928122	KR	2	participated in the study design, interpretation of statistical analyses, and manuscript preparation	participated in the study design, interpretation of statistical analyses, and manuscript preparation	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4792823	26928122	KWW	2	participated in the study design, interpretation of statistical analyses, and manuscript preparation	participated in the study design, interpretation of statistical analyses, and manuscript preparation	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5037900	27708678	CP	2	prepared various sections of the manuscript	prepared various sections of the manuscript	Wrote the paper	Writing - Original Draft	YES
5037900	27708678	GN	2	prepared various sections of the manuscript	prepared various sections of the manuscript	Wrote the paper	Writing - Original Draft	YES
5037900	27708678	S. All	2	authors read and approved the final manuscript	authors read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5037900	27708678	ST	2	prepared various sections of the manuscript	prepared various sections of the manuscript	Wrote the paper	Writing - Original Draft	YES
5513975	28769957	JP	2	conceived the idea, assisted in data interpretation, and critically reviewed and edited the manuscript	conceived the idea, assisted in data interpretation, and critically reviewed and edited the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Review & Editing	YES
5513975	28769957	KS	2	conceived the idea, assisted in data interpretation, and critically reviewed and edited the manuscript	conceived the idea, assisted in data interpretation, and critically reviewed and edited the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Review & Editing	YES
5513975	28769957	RS	2	has performed data acquisition, analysis and interpretation of the data and drafting of the manuscript|is the corresponding author of this manuscript	has performed data acquisition, analysis and interpretation of the data and drafting of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5513975	28769957	RS	2	has performed data acquisition, analysis and interpretation of the data and drafting of the manuscript|is the corresponding author of this manuscript	is the corresponding author of this manuscript	-	-	NO
4404318	25894391	AMM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404318	25894391	AMM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404318	25894391	AMM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404318	25894391	AMM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404318	25894391	AMM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404318	25894391	AR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404318	25894391	AR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404318	25894391	AR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404318	25894391	AR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404318	25894391	AR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404318	25894391	BS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404318	25894391	BS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404318	25894391	BS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404318	25894391	BS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404318	25894391	BS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404318	25894391	CA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404318	25894391	CA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404318	25894391	CA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404318	25894391	CA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404318	25894391	CA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404318	25894391	CW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404318	25894391	CW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404318	25894391	CW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404318	25894391	CW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404318	25894391	CW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404318	25894391	DAN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404318	25894391	DAN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404318	25894391	DAN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404318	25894391	DAN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404318	25894391	DAN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404318	25894391	PD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404318	25894391	PD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404318	25894391	PD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404318	25894391	PD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404318	25894391	PD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404318	25894391	VS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404318	25894391	VS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404318	25894391	VS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404318	25894391	VS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404318	25894391	VS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4522018	26232000	AC	2	conceived the study, collected the data, and contributed to writing the paper	conceived the study, collected the data, and contributed to writing the paper	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
4522018	26232000	AL	2	collected the data and contributed to writing the paper	collected the data and contributed to writing the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4522018	26232000	AP	2	made the statistical analyses and wrote the first draft of the paper	made the statistical analyses and wrote the first draft of the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4522018	26232000	GT	2	collected the data	collected the data	Performed the experiments	Investigation	YES
4522018	26232000	LG	2	made the statistical analyses and contributed to writing the paper	made the statistical analyses and contributed to writing the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4522018	26232000	MC	2	collected the data and contributed to writing the paper	collected the data and contributed to writing the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4522018	26232000	MM	2	collected the data	collected the data	Performed the experiments	Investigation	YES
4522018	26232000	NG	2	conceived the study, collected the data, and wrote the first draft of the paper	conceived the study, collected the data, and wrote the first draft of the paper	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
4522018	26232000	PC	2	collected the data and contributed to writing the paper	collected the data and contributed to writing the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4522018	26232000	SB	2	collected the data	collected the data	Performed the experiments	Investigation	YES
4522018	26232000	SN	2	collected the data and contributed to writing the paper	collected the data and contributed to writing the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4522018	26232000	VS	2	collected the data and contributed to writing the paper	collected the data and contributed to writing the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5419373	28970409	Irene Munro	2	contributed to implementing the study and took the lead in analysis and interpretation of the data and writing the manuscript	contributed to implementing the study and took the lead in analysis and interpretation of the data and writing the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft	YES
5419373	28970409	Jennifer Schneider	2	took the lead in designing and implementing the study, collecting the data, contributed to analysis and interpretation of the data, and writing of the manuscript	took the lead in designing and implementing the study, collecting the data, contributed to analysis and interpretation of the data, and writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
5419373	28970409	OHara	2	engaged in critical review and preparing the manuscript	engaged in critical review and preparing the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5225521	28077088	AK	PLoS52	designed the research|provided critical revisions to the intellectual content and supervised the study	designed the research	Conceived and designed the experiments	Methodology	YES
5225521	28077088	AK	PLoS52	designed the research|provided critical revisions to the intellectual content and supervised the study	provided critical revisions to the intellectual content and supervised the study	Wrote the paper	Supervision|Writing - Review & Editing	YES
5225521	28077088	ARM	PLoS52	designed the research|performed research and analyzed data	designed the research	Conceived and designed the experiments	Methodology	YES
5225521	28077088	ARM	PLoS52	designed the research|performed research and analyzed data	performed research and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5225521	28077088	ELA	PLoS52	performed research and analyzed data	performed research and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5225521	28077088	MA	PLoS52	performed research and analyzed data|wrote the paper	performed research and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5225521	28077088	MA	PLoS52	performed research and analyzed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5225521	28077088	MN	PLoS52	designed the research|provided critical revisions to the intellectual content and supervised the study	designed the research	Conceived and designed the experiments	Methodology	YES
5225521	28077088	MN	PLoS52	designed the research|provided critical revisions to the intellectual content and supervised the study	provided critical revisions to the intellectual content and supervised the study	Wrote the paper	Supervision|Writing - Review & Editing	YES
5225521	28077088	MP	PLoS52	performed research and analyzed data	performed research and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5225521	28077088	TR	PLoS52	performed research and analyzed data|wrote the paper	performed research and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5225521	28077088	TR	PLoS52	performed research and analyzed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5513976	28769967	EL	2	performed the literature review, analysis, drew conclusions, and wrote the article	performed the literature review, analysis, drew conclusions, and wrote the article	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5513976	28769967	SW	2	performed the literature review, analysis, drew conclusions, and wrote the article	performed the literature review, analysis, drew conclusions, and wrote the article	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5100316	27826353	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5100316	27826353	DSB	2	all contributed to the conceptualization, drafting, and editing of the manuscript	all contributed to the conceptualization, drafting, and editing of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
5100316	27826353	ESK	2	all contributed to the conceptualization, drafting, and editing of the manuscript	all contributed to the conceptualization, drafting, and editing of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
5100316	27826353	MJM	2	all contributed to the conceptualization, drafting, and editing of the manuscript	all contributed to the conceptualization, drafting, and editing of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
4524888	26242311	AM	2	assisted with patient recruitment, clinical care and data collection	assisted with patient recruitment, clinical care and data collection	Performed the experiments	Investigation	YES
4524888	26242311	BK	2	assisted with patient recruitment, clinical care and data collection	assisted with patient recruitment, clinical care and data collection	Performed the experiments	Investigation	YES
4524888	26242311	BMD	2	processed and interpreted all pathologic specimens	processed and interpreted all pathologic specimens	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4524888	26242311	CK	2	processed and interpreted all pathologic specimens	processed and interpreted all pathologic specimens	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4524888	26242311	DPD	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
4524888	26242311	MC	2	assisted with patient recruitment, clinical care and data collection	assisted with patient recruitment, clinical care and data collection	Performed the experiments	Investigation	YES
4524888	26242311	NDM	2	processed and interpreted all pathologic specimens	processed and interpreted all pathologic specimens	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4524888	26242311	NGL	2	designed the study|processed and interpreted all pathologic specimens	designed the study	Conceived and designed the experiments	Methodology	YES
4524888	26242311	NGL	2	designed the study|processed and interpreted all pathologic specimens	processed and interpreted all pathologic specimens	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4524888	26242311	RK	2	processed and interpreted all pathologic specimens	processed and interpreted all pathologic specimens	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4524888	26242311	RN	2	assisted with patient recruitment, clinical care and data collection	assisted with patient recruitment, clinical care and data collection	Performed the experiments	Investigation	YES
4524888	26242311	SG	2	designed the study|recruited patients, provided clinical care, collected data, analyzed data and wrote the first draft of the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
4524888	26242311	SG	2	designed the study|recruited patients, provided clinical care, collected data, analyzed data and wrote the first draft of the manuscript	recruited patients, provided clinical care, collected data, analyzed data and wrote the first draft of the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft	YES
4524888	26242311	YF	2	designed the study|processed and interpreted all pathologic specimens	designed the study	Conceived and designed the experiments	Methodology	YES
4524888	26242311	YF	2	designed the study|processed and interpreted all pathologic specimens	processed and interpreted all pathologic specimens	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4524888	26242311	all authors	2	reviewed and commented on the manuscript and approved the final submitted version	reviewed and commented on the manuscript and approved the final submitted version	Wrote the paper	Writing - Review & Editing	YES
4404320	25893872	EG	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404320	25893872	EG	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404320	25893872	EG	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404320	25893872	EG	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404320	25893872	ES	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Contributed to revising the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404320	25893872	ES	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Contributed to revising the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404320	25893872	ES	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Contributed to revising the manuscript	Contributed to revising the manuscript	Wrote the paper	Writing - Review & Editing	YES
4404320	25893872	MD	PLoS5	Conceived and designed the experiments|Contributed to revising the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404320	25893872	MD	PLoS5	Conceived and designed the experiments|Contributed to revising the manuscript	Contributed to revising the manuscript	Wrote the paper	Writing - Review & Editing	YES
4404320	25893872	MV	PLoS5	Contributed reagents/materials/analysis tools|Contributed to revising the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404320	25893872	MV	PLoS5	Contributed reagents/materials/analysis tools|Contributed to revising the manuscript	Contributed to revising the manuscript	Wrote the paper	Writing - Review & Editing	YES
4404320	25893872	NF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404320	25893872	NF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404320	25893872	NF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404320	25893872	NF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404320	25893872	NF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5419374	28970402	Aleksandra Sokirskaja	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5419374	28970402	Baiba Maurina	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5419374	28970402	Daisy Volmer	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5419374	28970402	Daisy Volmer	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5419374	28970402	Daisy Volmer	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5419374	28970402	Daisy Volmer	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5419374	28970402	Ingunn Bjornsdottir	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5419374	28970402	Jurgita Dauksiene	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5419374	28970402	Jyrki Heinamaki	PLoS52	conceived and designed the experiments|analyzed the data|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5419374	28970402	Jyrki Heinamaki	PLoS52	conceived and designed the experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5419374	28970402	Jyrki Heinamaki	PLoS52	conceived and designed the experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5419374	28970402	Kirsti Vainio	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5419374	28970402	Kjell H. Halvorsen	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5419374	28970402	Lilian Ruuben	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5419374	28970402	Niklas Sandler	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5419374	28970402	Raisa Laaksonen	PLoS52	conceived and designed the experiments|performed the experiments|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5419374	28970402	Raisa Laaksonen	PLoS52	conceived and designed the experiments|performed the experiments|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5419374	28970402	Raisa Laaksonen	PLoS52	conceived and designed the experiments|performed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5419374	28970402	Reidun Kjome	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5419374	28970402	Ruta Muceniece	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5419374	28970402	Sveinbjorn Gizurarson	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5419374	28970402	Tagne Ratassepp	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
4828347	27068058	All authors	2	contributed to the final manuscript|read and approved the final manuscript	contributed to the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4828347	27068058	All authors	2	contributed to the final manuscript|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4828347	27068058	SM	2	were involved in the draft manuscript	were involved in the draft manuscript	Wrote the paper	Writing - Original Draft	YES
4828347	27068058	TG	2	were involved in the draft manuscript	were involved in the draft manuscript	Wrote the paper	Writing - Original Draft	YES
5552244	28750860	AP	2	wrote the first drafts of the manuscript, which was then edited by all authors	wrote the first drafts of the manuscript, which was then edited by all authors	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5552244	28750860	AS	2	reviewed the histology and carried out and interpreted the immunohistochemistry	reviewed the histology and carried out and interpreted the immunohistochemistry	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5552244	28750860	BA	2	originated the study, obtained funding, supervised the clinical data collection and carried out the first analysis of the data|wrote the first drafts of the manuscript, which was then edited by all authors	originated the study, obtained funding, supervised the clinical data collection and carried out the first analysis of the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Funding acquisition|Investigation|Supervision	YES
5552244	28750860	BA	2	originated the study, obtained funding, supervised the clinical data collection and carried out the first analysis of the data|wrote the first drafts of the manuscript, which was then edited by all authors	wrote the first drafts of the manuscript, which was then edited by all authors	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5552244	28750860	EB	2	contributed to data generation and analysis and development of laboratory protocols and morphometry	contributed to data generation and analysis and development of laboratory protocols and morphometry	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5552244	28750860	JL-A	2	contributed to data generation and analysis and development of laboratory protocols and morphometry	contributed to data generation and analysis and development of laboratory protocols and morphometry	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5552244	28750860	JRT	2	reviewed the histology and carried out and interpreted the immunohistochemistry	reviewed the histology and carried out and interpreted the immunohistochemistry	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5552244	28750860	KC	2	contributed to data generation and analysis and development of laboratory protocols and morphometry	contributed to data generation and analysis and development of laboratory protocols and morphometry	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5552244	28750860	KZ	2	contributed to data generation and analysis and development of laboratory protocols and morphometry	contributed to data generation and analysis and development of laboratory protocols and morphometry	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5552244	28750860	PK	2	originated the study, obtained funding, supervised the clinical data collection and carried out the first analysis of the data|contributed to data generation and analysis and development of laboratory protocols and morphometry|wrote the first drafts of the manuscript, which was then edited by all authors	originated the study, obtained funding, supervised the clinical data collection and carried out the first analysis of the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Funding acquisition|Investigation|Supervision	YES
5552244	28750860	PK	2	originated the study, obtained funding, supervised the clinical data collection and carried out the first analysis of the data|contributed to data generation and analysis and development of laboratory protocols and morphometry|wrote the first drafts of the manuscript, which was then edited by all authors	contributed to data generation and analysis and development of laboratory protocols and morphometry	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5552244	28750860	PK	2	originated the study, obtained funding, supervised the clinical data collection and carried out the first analysis of the data|contributed to data generation and analysis and development of laboratory protocols and morphometry|wrote the first drafts of the manuscript, which was then edited by all authors	wrote the first drafts of the manuscript, which was then edited by all authors	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5552244	28750860	SY	2	reviewed the histology and carried out and interpreted the immunohistochemistry	reviewed the histology and carried out and interpreted the immunohistochemistry	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5552244	28750860	WF	2	contributed the lactulose/rhamnose testing and its analysis and interpretation	contributed the lactulose/rhamnose testing and its analysis and interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5225542	28073363	CB	2	developed the particle dispersal software and refined it for this investigation, participated in the investigation design, and edited the manuscript	developed the particle dispersal software and refined it for this investigation, participated in the investigation design, and edited the manuscript	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Software|Writing - Original Draft|Writing - Review & Editing	YES
5225542	28073363	DRJ	2	participated in the investigation design, provided supervisory support and edited the manuscript	participated in the investigation design, provided supervisory support and edited the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Review & Editing	YES
5225542	28073363	KRZ	2	participated in design and conceptualisation of the project, provided statistical advice and technical input on investigation design, provided supervisory support and edited the manuscript	participated in design and conceptualisation of the project, provided statistical advice and technical input on investigation design, provided supervisory support and edited the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Supervision|Writing - Review & Editing	YES
5225542	28073363	MML	2	carried out all tissue collections, laboratory bench work, participated in the investigation design and conceptualisation, developed modifications to the genotyping protocol, performed all data analyses and drafted the manuscript	carried out all tissue collections, laboratory bench work, participated in the investigation design and conceptualisation, developed modifications to the genotyping protocol, performed all data analyses and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5225542	28073363	PCS	2	developed the broad project concept, participated in the investigation design, provided supervisory support, all project funding, advice on pearl oyster biology and ecology, and edited the manuscript	developed the broad project concept, participated in the investigation design, provided supervisory support, all project funding, advice on pearl oyster biology and ecology, and edited the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Funding acquisition|Investigation|Methodology|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
4786756	27006766	Augusto Diogo Filho	7	Study design, data collection, analysis, writing	Study design, data collection, analysis, writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology	YES
4786756	27006766	Kleber Gontijo	7	Study design, data collection, analysis, writing	Study design, data collection, analysis, writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology	YES
4786756	27006766	Paulo Cesar Santos	7	Study design, data collection, analysis, writing	Study design, data collection, analysis, writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology	YES
5419375	28970408	Akosua Adom Agyeman	2	contributed to manuscript preparation and revision	contributed to manuscript preparation and revision	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5419375	28970408	Richard Ofori-Asenso	2	contributed to manuscript preparation and revision	contributed to manuscript preparation and revision	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5103612	27843481	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5103612	27843481	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5103612	27843481	all of the authors	2	have appropriate permission for the data we used	have appropriate permission for the data we used	-	-	NO
5513978	28769966	All the authors	2	have read and approved the final version of the manuscript	have read and approved the final version of the manuscript	-	-	NO
5513978	28769966	MM	2	improved the manuscript and provided revisions to the manuscript	improved the manuscript and provided revisions to the manuscript	Wrote the paper	Writing - Review & Editing	YES
5513978	28769966	MP	2	conceived the idea and drafted the opinion article	conceived the idea and drafted the opinion article	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5513978	28769966	TB	2	conceived the idea and drafted the opinion article	conceived the idea and drafted the opinion article	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4528077	26249127	BW	2	carried out study conceptualization, research execution, field operations, manuscript preparation	carried out study conceptualization, research execution, field operations, manuscript preparation	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
4528077	26249127	CC	2	carried out study conceptualization, research execution, field operations, manuscript preparation	carried out study conceptualization, research execution, field operations, manuscript preparation	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
4528077	26249127	CK	2	performed study conceptualization, field operations, manuscript preparation	performed study conceptualization, field operations, manuscript preparation	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
4528077	26249127	CM	2	carried out study conceptualization, research execution, field operations, manuscript preparation	carried out study conceptualization, research execution, field operations, manuscript preparation	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
4528077	26249127	CW	2	carried out study conceptualization, research execution, field operations, manuscript preparation	carried out study conceptualization, research execution, field operations, manuscript preparation	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
4528077	26249127	JP	2	did study conceptualization, data analyses, field operations, manuscript preparation	did study conceptualization, data analyses, field operations, manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
4528077	26249127	MOK	2	handled study design, conceptualization, research execution, field operations, manuscript preparation	handled study design, conceptualization, research execution, field operations, manuscript preparation	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Writing - Original Draft	YES
4528077	26249127	SCK	2	performed study design, data analyses, manuscript preparation	performed study design, data analyses, manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4528077	26249127	TG	2	performed study conceptualization, data analyses, manuscript preparation	performed study conceptualization, data analyses, manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
4875582	27207565	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4875582	27207565	ELF	2	did the statistical analyses	did the statistical analyses	Analyzed the data	Formal analysis	YES
4875582	27207565	FB	2	contributed to the patients inclusion	contributed to the patients inclusion	-	-	NO
4875582	27207565	JFD	2	did the statistical analyses	did the statistical analyses	Analyzed the data	Formal analysis	YES
4875582	27207565	JO	2	coordinated the study and wrote the manuscript	coordinated the study and wrote the manuscript	Wrote the paper	Project administration|Writing - Original Draft	YES
4875582	27207565	ML	2	coordinated the study and wrote the manuscript	coordinated the study and wrote the manuscript	Wrote the paper	Project administration|Writing - Original Draft	YES
4875582	27207565	NH	2	contributed to the patients inclusion	contributed to the patients inclusion	-	-	NO
4875582	27207565	RT	2	coordinated the study and wrote the manuscript	coordinated the study and wrote the manuscript	Wrote the paper	Project administration|Writing - Original Draft	YES
4875582	27207565	RY	2	did the analysis of infectious stigma	did the analysis of infectious stigma	-	-	NO
4875582	27207565	Rajagopal Krishnamoorthy	2	coordinated the study and wrote the manuscript	coordinated the study and wrote the manuscript	Wrote the paper	Project administration|Writing - Original Draft	YES
4875582	27207565	Remi Kazma	2	did the statistical analyses	did the statistical analyses	Analyzed the data	Formal analysis	YES
4404321	25893847	CBA	PLoS5	Performed the interpretation of the results|Edited the manuscript	Performed the interpretation of the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4404321	25893847	CBA	PLoS5	Performed the interpretation of the results|Edited the manuscript	Edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
4404321	25893847	JA	PLoS5	Wrote the paper|Conceived and performed the computational analysis|Performed the interpretation of the results|Edited the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404321	25893847	JA	PLoS5	Wrote the paper|Conceived and performed the computational analysis|Performed the interpretation of the results|Edited the manuscript	Conceived and performed the computational analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation	YES
4404321	25893847	JA	PLoS5	Wrote the paper|Conceived and performed the computational analysis|Performed the interpretation of the results|Edited the manuscript	Performed the interpretation of the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4404321	25893847	JA	PLoS5	Wrote the paper|Conceived and performed the computational analysis|Performed the interpretation of the results|Edited the manuscript	Edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
4404321	25893847	LB	PLoS5	Wrote the paper|Performed the interpretation of the results|Edited the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404321	25893847	LB	PLoS5	Wrote the paper|Performed the interpretation of the results|Edited the manuscript	Performed the interpretation of the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4404321	25893847	LB	PLoS5	Wrote the paper|Performed the interpretation of the results|Edited the manuscript	Edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
4404321	25893847	MG	PLoS5	Performed the interpretation of the results|Edited the manuscript	Performed the interpretation of the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4404321	25893847	MG	PLoS5	Performed the interpretation of the results|Edited the manuscript	Edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
4404321	25893847	MJ	PLoS5	Performed the interpretation of the results|Edited the manuscript	Performed the interpretation of the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4404321	25893847	MJ	PLoS5	Performed the interpretation of the results|Edited the manuscript	Edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
4404321	25893847	SH	PLoS5	Performed the interpretation of the results|Edited the manuscript	Performed the interpretation of the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4404321	25893847	SH	PLoS5	Performed the interpretation of the results|Edited the manuscript	Edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
4786758	27006767	MR	2	write draft of manuscript	write draft of manuscript	Wrote the paper	Writing - Original Draft	YES
4786758	27006767	S Djati	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5419376	28970404	Brian McKinzie	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5419376	28970404	Each author	PLoS52	helped write the manuscript and contributed questions to the examination	helped write the manuscript and contributed questions to the examination	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5419376	28970404	Jason Haney	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5552245	28774738	B.M.S.	2	drafted all or parts of the article, with input from other authors|obtained the funding and supervised the study	drafted all or parts of the article, with input from other authors	Wrote the paper	Writing - Original Draft	YES
5552245	28774738	B.M.S.	2	drafted all or parts of the article, with input from other authors|obtained the funding and supervised the study	obtained the funding and supervised the study	-	Funding acquisition|Supervision	YES
5552245	28774738	C.C.Z.	2	acquired the data|analyzed all or parts of the data|drafted all or parts of the article, with input from other authors	acquired the data	Performed the experiments	Investigation	YES
5552245	28774738	C.C.Z.	2	acquired the data|analyzed all or parts of the data|drafted all or parts of the article, with input from other authors	analyzed all or parts of the data	Analyzed the data	Formal analysis	YES
5552245	28774738	C.C.Z.	2	acquired the data|analyzed all or parts of the data|drafted all or parts of the article, with input from other authors	drafted all or parts of the article, with input from other authors	Wrote the paper	Writing - Original Draft	YES
5552245	28774738	K.Z.	2	analyzed all or parts of the data	analyzed all or parts of the data	Analyzed the data	Formal analysis	YES
5552245	28774738	Q.F.	2	acquired the data|analyzed all or parts of the data	acquired the data	Performed the experiments	Investigation	YES
5552245	28774738	Q.F.	2	acquired the data|analyzed all or parts of the data	analyzed all or parts of the data	Analyzed the data	Formal analysis	YES
5552245	28774738	Q.M.L.	2	acquired the data|analyzed all or parts of the data|drafted all or parts of the article, with input from other authors	acquired the data	Performed the experiments	Investigation	YES
5552245	28774738	Q.M.L.	2	acquired the data|analyzed all or parts of the data|drafted all or parts of the article, with input from other authors	analyzed all or parts of the data	Analyzed the data	Formal analysis	YES
5552245	28774738	Q.M.L.	2	acquired the data|analyzed all or parts of the data|drafted all or parts of the article, with input from other authors	drafted all or parts of the article, with input from other authors	Wrote the paper	Writing - Original Draft	YES
5552245	28774738	Q.Z.	2	acquired the data|analyzed all or parts of the data	acquired the data	Performed the experiments	Investigation	YES
5552245	28774738	Q.Z.	2	acquired the data|analyzed all or parts of the data	analyzed all or parts of the data	Analyzed the data	Formal analysis	YES
5552245	28774738	Z.P.X.	2	were responsible for the concept and the design of the study|drafted all or parts of the article, with input from other authors	were responsible for the concept and the design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5552245	28774738	Z.P.X.	2	were responsible for the concept and the design of the study|drafted all or parts of the article, with input from other authors	drafted all or parts of the article, with input from other authors	Wrote the paper	Writing - Original Draft	YES
5552245	28774738	Zhen Wang	2	acquired the data|analyzed all or parts of the data|drafted all or parts of the article, with input from other authors	acquired the data	Performed the experiments	Investigation	YES
5552245	28774738	Zhen Wang	2	acquired the data|analyzed all or parts of the data|drafted all or parts of the article, with input from other authors	analyzed all or parts of the data	Analyzed the data	Formal analysis	YES
5552245	28774738	Zhen Wang	2	acquired the data|analyzed all or parts of the data|drafted all or parts of the article, with input from other authors	drafted all or parts of the article, with input from other authors	Wrote the paper	Writing - Original Draft	YES
5552245	28774738	Zheng Wang	2	were responsible for the concept and the design of the study|drafted all or parts of the article, with input from other authors|obtained the funding and supervised the study	were responsible for the concept and the design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5552245	28774738	Zheng Wang	2	were responsible for the concept and the design of the study|drafted all or parts of the article, with input from other authors|obtained the funding and supervised the study	drafted all or parts of the article, with input from other authors	Wrote the paper	Writing - Original Draft	YES
5552245	28774738	Zheng Wang	2	were responsible for the concept and the design of the study|drafted all or parts of the article, with input from other authors|obtained the funding and supervised the study	obtained the funding and supervised the study	-	Funding acquisition|Supervision	YES
4530137	26257204	AH	2	conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4530137	26257204	NF	2	conceived the study|wrote the first draft with input from all the authors who then also contributed to, read, and approved the final paper	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4530137	26257204	NF	2	conceived the study|wrote the first draft with input from all the authors who then also contributed to, read, and approved the final paper	wrote the first draft with input from all the authors who then also contributed to, read, and approved the final paper	Wrote the paper	Writing - Original Draft	YES
4469788	26146636	Yuanyuan Chen	2	contributed equally to this work	contributed equally to this work	-	-	NO
4469788	26146636	Yuejin Zhang	2	contributed equally to this work	contributed equally to this work	-	-	NO
5225578	28077071	GL	2	performed the field experiments	performed the field experiments	Performed the experiments	Investigation	YES
5225578	28077071	HW	2	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5225578	28077071	JS	2	designed the experiments|performed the construction, genotyping and phenotyping of the ril population|conducted the data analysis and wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5225578	28077071	JS	2	designed the experiments|performed the construction, genotyping and phenotyping of the ril population|conducted the data analysis and wrote the manuscript	performed the construction, genotyping and phenotyping of the ril population	Performed the experiments	Investigation	YES
5225578	28077071	JS	2	designed the experiments|performed the construction, genotyping and phenotyping of the ril population|conducted the data analysis and wrote the manuscript	conducted the data analysis and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5225578	28077071	JY	2	performed qtl scanning and expression analysis|conducted the data analysis and wrote the manuscript	performed qtl scanning and expression analysis	Performed the experiments	Investigation	YES
5225578	28077071	JY	2	performed qtl scanning and expression analysis|conducted the data analysis and wrote the manuscript	conducted the data analysis and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5225578	28077071	XW	2	performed the field experiments	performed the field experiments	Performed the experiments	Investigation	YES
5225578	28077071	YY	2	collected samples and prepared rna	collected samples and prepared rna	Performed the experiments	Investigation	YES
5513985	28769970	AA	PLoS52	analyzed the data|edited and provided critical review of the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5513985	28769970	AA	PLoS52	analyzed the data|edited and provided critical review of the manuscript	edited and provided critical review of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5513985	28769970	AA-A	PLoS52	analyzed the data|edited and provided critical review of the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5513985	28769970	AA-A	PLoS52	analyzed the data|edited and provided critical review of the manuscript	edited and provided critical review of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5513985	28769970	AF-M	PLoS52	analyzed the data|edited and provided critical review of the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5513985	28769970	AF-M	PLoS52	analyzed the data|edited and provided critical review of the manuscript	edited and provided critical review of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5513985	28769970	AS	PLoS52	conceived and designed the experiments|performed the laboratory procedures|analyzed the data|edited and provided critical review of the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5513985	28769970	AS	PLoS52	conceived and designed the experiments|performed the laboratory procedures|analyzed the data|edited and provided critical review of the manuscript	performed the laboratory procedures	Performed the experiments	Investigation	YES
5513985	28769970	AS	PLoS52	conceived and designed the experiments|performed the laboratory procedures|analyzed the data|edited and provided critical review of the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5513985	28769970	AS	PLoS52	conceived and designed the experiments|performed the laboratory procedures|analyzed the data|edited and provided critical review of the manuscript	edited and provided critical review of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5513985	28769970	BB	PLoS52	analyzed the data|edited and provided critical review of the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5513985	28769970	BB	PLoS52	analyzed the data|edited and provided critical review of the manuscript	edited and provided critical review of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5513985	28769970	FB	PLoS52	conceived and designed the experiments|analyzed the data|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5513985	28769970	FB	PLoS52	conceived and designed the experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5513985	28769970	FB	PLoS52	conceived and designed the experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5513985	28769970	HK	PLoS52	conceived and designed the experiments|performed the laboratory procedures|analyzed the data|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5513985	28769970	HK	PLoS52	conceived and designed the experiments|performed the laboratory procedures|analyzed the data|wrote the paper	performed the laboratory procedures	Performed the experiments	Investigation	YES
5513985	28769970	HK	PLoS52	conceived and designed the experiments|performed the laboratory procedures|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5513985	28769970	HK	PLoS52	conceived and designed the experiments|performed the laboratory procedures|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5513985	28769970	MG	PLoS52	performed the laboratory procedures|analyzed the data|edited and provided critical review of the manuscript	performed the laboratory procedures	Performed the experiments	Investigation	YES
5513985	28769970	MG	PLoS52	performed the laboratory procedures|analyzed the data|edited and provided critical review of the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5513985	28769970	MG	PLoS52	performed the laboratory procedures|analyzed the data|edited and provided critical review of the manuscript	edited and provided critical review of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5513985	28769970	RO	PLoS52	conceived and designed the experiments|analyzed the data|edited and provided critical review of the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5513985	28769970	RO	PLoS52	conceived and designed the experiments|analyzed the data|edited and provided critical review of the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5513985	28769970	RO	PLoS52	conceived and designed the experiments|analyzed the data|edited and provided critical review of the manuscript	edited and provided critical review of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5105323	27857775	All authors	2	reviewed the data analysis|read and approved the final manuscript	reviewed the data analysis	Analyzed the data	Formal analysis	YES
5105323	27857775	All authors	2	reviewed the data analysis|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5105323	27857775	DR	2	reviewed and analyzed the data	reviewed and analyzed the data	Analyzed the data	Formal analysis	YES
5105323	27857775	FN	2	facilitated the data collection and project oversite	facilitated the data collection and project oversite	Performed the experiments	Investigation	YES
5105323	27857775	JSS	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5105323	27857775	MR	2	reviewed and analyzed the data	reviewed and analyzed the data	Analyzed the data	Formal analysis	YES
5105323	27857775	NN	2	reviewed and analyzed the data|facilitated the data collection and project oversite	reviewed and analyzed the data	Analyzed the data	Formal analysis	YES
5105323	27857775	NN	2	reviewed and analyzed the data|facilitated the data collection and project oversite	facilitated the data collection and project oversite	Performed the experiments	Investigation	YES
5105323	27857775	SM	2	designed the study|designed the study instruments|reviewed and analyzed the data	designed the study	Conceived and designed the experiments	Methodology	YES
5105323	27857775	SM	2	designed the study|designed the study instruments|reviewed and analyzed the data	designed the study instruments	Conceived and designed the experiments	Methodology	YES
5105323	27857775	SM	2	designed the study|designed the study instruments|reviewed and analyzed the data	reviewed and analyzed the data	Analyzed the data	Formal analysis	YES
5105323	27857775	The authors	2	declare that they have no competing intrests	declare that they have no competing intrests	-	-	NO
4404322	25893501	JJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404322	25893501	JJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404322	25893501	JJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404322	25893501	JJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404322	25893501	JP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404322	25893501	JP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404322	25893501	JP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404322	25893501	JP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404322	25893501	JP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404322	25893501	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404322	25893501	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404322	25893501	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404322	25893501	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404322	25893501	KP	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404322	25893501	KP	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404322	25893501	KP	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404322	25893501	KP	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404322	25893501	LD	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404322	25893501	LD	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404322	25893501	LD	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404322	25893501	LD	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404322	25893501	LK	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404322	25893501	LK	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404322	25893501	LK	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404322	25893501	LK	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404322	25893501	MP	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404322	25893501	MP	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404322	25893501	MP	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404322	25893501	MP	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404322	25893501	MT	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404322	25893501	MT	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404322	25893501	MT	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404322	25893501	MT	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404322	25893501	OT	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404322	25893501	OT	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404322	25893501	OT	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404322	25893501	OT	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404322	25893501	P. Kala	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404322	25893501	P. Kala	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404322	25893501	P. Kala	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404322	25893501	P. Kala	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404322	25893501	P. Kubena	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404322	25893501	P. Kubena	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404322	25893501	P. Kubena	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404322	25893501	P. Kubena	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404322	25893501	SL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404322	25893501	SL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404322	25893501	SL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404322	25893501	SL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4882311	27230036	AD	2	as senior author	as senior author	-	-	NO
4882311	27230036	All authors	2	significantly contributed to and are in agreement with the content of this paper|contributed to research question development, interpretation of the findings and editing of the manuscript|read and approved the final manuscript	significantly contributed to and are in agreement with the content of this paper	-	-	NO
4882311	27230036	All authors	2	significantly contributed to and are in agreement with the content of this paper|contributed to research question development, interpretation of the findings and editing of the manuscript|read and approved the final manuscript	contributed to research question development, interpretation of the findings and editing of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
4882311	27230036	All authors	2	significantly contributed to and are in agreement with the content of this paper|contributed to research question development, interpretation of the findings and editing of the manuscript|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4882311	27230036	Bernard Carroll	2	for his thoughtful assistance with this paper	for his thoughtful assistance with this paper	-	-	NO
4882311	27230036	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
4796663	27047660	Chinmay Gupte	7	study design, review paper	study design, review paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
4796663	27047660	Helgi Johannsson	7	study design, review paper	study design, review paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
4796663	27047660	Rajarshi Bhattacharya	7	study design, review paper	study design, review paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
4796663	27047660	Sanjeeve Sabharwal	7	study design, data analysis, writing	study design, data analysis, writing	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology	YES
4796663	27047660	Wan Wei Ang	7	study design, data collections, data analysis, writing	study design, data collections, data analysis, writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology	YES
5552246	28733045	R.H.	2	designed research, analyzed data, and wrote the manuscript|supervised the overall project	designed research, analyzed data, and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5552246	28733045	R.H.	2	designed research, analyzed data, and wrote the manuscript|supervised the overall project	supervised the overall project	-	Supervision	YES
5552246	28733045	T.I.	2	designed research, analyzed data, and wrote the manuscript	designed research, analyzed data, and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4534712	26268817	AC	2	led the conceptualization and design of the study, with contributions from all authors|interpreted the results and wrote the first draft of the paper, with contributions from all authors	led the conceptualization and design of the study, with contributions from all authors	Conceived and designed the experiments	Conceptualization|Methodology	YES
4534712	26268817	AC	2	led the conceptualization and design of the study, with contributions from all authors|interpreted the results and wrote the first draft of the paper, with contributions from all authors	interpreted the results and wrote the first draft of the paper, with contributions from all authors	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4534712	26268817	JF	2	led the conceptualization and design of the study, with contributions from all authors	led the conceptualization and design of the study, with contributions from all authors	Conceived and designed the experiments	Conceptualization|Methodology	YES
4534712	26268817	RSH	2	has full access to all the data in the study and takes responsibility for the integrity of the data, the accuracy of the data analysis and the final decision to submit for publication|led the conceptualization and design of the study, with contributions from all authors	has full access to all the data in the study and takes responsibility for the integrity of the data, the accuracy of the data analysis and the final decision to submit for publication	Analyzed the data	Data curation|Formal analysis	YES
4534712	26268817	RSH	2	has full access to all the data in the study and takes responsibility for the integrity of the data, the accuracy of the data analysis and the final decision to submit for publication|led the conceptualization and design of the study, with contributions from all authors	led the conceptualization and design of the study, with contributions from all authors	Conceived and designed the experiments	Conceptualization|Methodology	YES
4534712	26268817	ZC	2	ran the analysis of data	ran the analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4534712	26268817	all authors	2	for important intellectual content	for important intellectual content	-	-	NO
5419378	28970405	Fekadu Fullas	2	jointly conceived the idea and design of the project|analyzed the data and wrote the paper	jointly conceived the idea and design of the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5419378	28970405	Fekadu Fullas	2	jointly conceived the idea and design of the project|analyzed the data and wrote the paper	analyzed the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5419378	28970405	James Stratton	2	jointly conceived the idea and design of the project	jointly conceived the idea and design of the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5419378	28970405	Kristel Nelson	2	jointly conceived the idea and design of the project	jointly conceived the idea and design of the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5419378	28970405	Lesleigh Ailts	2	jointly conceived the idea and design of the project	jointly conceived the idea and design of the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5419378	28970405	Michael Padomek	2	jointly conceived the idea and design of the project	jointly conceived the idea and design of the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5419378	28970405	Samuel Huber	2	jointly conceived the idea and design of the project|collected the data|analyzed the data and wrote the paper	jointly conceived the idea and design of the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5419378	28970405	Samuel Huber	2	jointly conceived the idea and design of the project|collected the data|analyzed the data and wrote the paper	collected the data	Performed the experiments	Investigation	YES
5419378	28970405	Samuel Huber	2	jointly conceived the idea and design of the project|collected the data|analyzed the data and wrote the paper	analyzed the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5225596	28077078	JY	PLoS52	conducted some qpcr analysis	conducted some qpcr analysis	Performed the experiments	Investigation	YES
5225596	28077078	MD	PLoS52	conducted the experiments, analyzed the data and wrote the draft manuscript	conducted the experiments, analyzed the data and wrote the draft manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5225596	28077078	PC	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5225596	28077078	RA	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5225596	28077078	SD	PLoS52	designed the study, supervised all aspects of the project and prepared final draft manuscript	designed the study, supervised all aspects of the project and prepared final draft manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Original Draft	YES
4802393	27054035	Athanasios Tampakis	7	design of the study, writing of the manuscript	design of the study, writing of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4802393	27054035	Ekaterini Christina Tampaki	7	writing of the manuscript	writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
4802393	27054035	Other Authors	7	Corrections	Corrections	-	-	NO
5552247	28754303	C.A.G.	2	designed experiments, interpreted data, and wrote the manuscript	designed experiments, interpreted data, and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5552247	28754303	I.L.	2	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5552247	28754303	K.S.	2	performed experiments, analyzed data and edited the manuscript	performed experiments, analyzed data and edited the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
5552247	28754303	S.T.	2	performed experiments, analyzed data and edited the manuscript	performed experiments, analyzed data and edited the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
5552247	28754303	T.E.	2	performed experiments, analyzed data and edited the manuscript	performed experiments, analyzed data and edited the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
5552247	28754303	U.K.	2	designed experiments and critically reviewed the paper	designed experiments and critically reviewed the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5552247	28754303	V.D.	2	designed and performed experiments	designed and performed experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4404324	25893665	AJB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404324	25893665	AJB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404324	25893665	AJB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404324	25893665	AJB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404324	25893665	BNK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404324	25893665	BNK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404324	25893665	CHH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4404324	25893665	CHH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4404324	25893665	CHH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404324	25893665	FRD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404324	25893665	FRD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404324	25893665	FRD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404324	25893665	LC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404324	25893665	LRO	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4404324	25893665	LRO	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4404324	25893665	LRO	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404324	25893665	SDK	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404324	25893665	SDK	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5109648	27891160	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5513986	28769949	AC	2	collected data	collected data	Performed the experiments	Investigation	YES
5513986	28769949	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5513986	28769949	BC	2	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5513986	28769949	DJ	2	collected data|analyzed data|revised the manuscript	collected data	Performed the experiments	Investigation	YES
5513986	28769949	DJ	2	collected data|analyzed data|revised the manuscript	analyzed data	Analyzed the data	Formal analysis	YES
5513986	28769949	DJ	2	collected data|analyzed data|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5513986	28769949	EM	2	collected data|analyzed data|wrote the manuscript	collected data	Performed the experiments	Investigation	YES
5513986	28769949	EM	2	collected data|analyzed data|wrote the manuscript	analyzed data	Analyzed the data	Formal analysis	YES
5513986	28769949	EM	2	collected data|analyzed data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5513986	28769949	EV	2	analyzed data|revised the manuscript	analyzed data	Analyzed the data	Formal analysis	YES
5513986	28769949	EV	2	analyzed data|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5513986	28769949	IG	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5513986	28769949	JB	2	analyzed data|revised the manuscript	analyzed data	Analyzed the data	Formal analysis	YES
5513986	28769949	JB	2	analyzed data|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5513986	28769949	ST	2	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5513986	28769949	XZ	2	collected data	collected data	Performed the experiments	Investigation	YES
5513986	28769949	YT	2	collected data|analyzed data|wrote the manuscript	collected data	Performed the experiments	Investigation	YES
5513986	28769949	YT	2	collected data|analyzed data|wrote the manuscript	analyzed data	Analyzed the data	Formal analysis	YES
5513986	28769949	YT	2	collected data|analyzed data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4936996	27389787	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4936996	27389787	BK	2	participated equally in the conception and design of the study|selected and reviewed the literature and drafted the manuscript	participated equally in the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4936996	27389787	BK	2	participated equally in the conception and design of the study|selected and reviewed the literature and drafted the manuscript	selected and reviewed the literature and drafted the manuscript	Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
4936996	27389787	CGL	2	participated in the conception of the study and writing the manuscript	participated in the conception of the study and writing the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4936996	27389787	EFC	2	participated equally in the conception and design of the study|selected and reviewed the literature and drafted the manuscript	participated equally in the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4936996	27389787	EFC	2	participated equally in the conception and design of the study|selected and reviewed the literature and drafted the manuscript	selected and reviewed the literature and drafted the manuscript	Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
4936996	27389787	The authors	2	declare that they have no competing interests|assert that all procedures contributing to this work comply with the ethical standards of the relevant national and institutional committees on human experimentation and with the helsinki declaration of 1975, as revised in 2008	declare that they have no competing interests	-	-	NO
4936996	27389787	The authors	2	declare that they have no competing interests|assert that all procedures contributing to this work comply with the ethical standards of the relevant national and institutional committees on human experimentation and with the helsinki declaration of 1975, as revised in 2008	assert that all procedures contributing to this work comply with the ethical standards of the relevant national and institutional committees on human experimentation and with the helsinki declaration of 1975, as revised in 2008	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5419379	28970407	All authors	2	contributed to study design, study execution, analysis of results, and manuscript preparation	contributed to study design, study execution, analysis of results, and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4542291	26290331	F. All	2	authors provided critical revisions and read and approved the final manuscript	authors provided critical revisions and read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4802398	27054032	EPW	2	is the main author who conceived and did the review	is the main author who conceived and did the review	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4802398	27054032	VV	2	contributed with literature search	contributed with literature search	-	Formal analysis	YES
4404325	25893251	AJ	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404325	25893251	AJ	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4404325	25893251	AMD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404325	25893251	AMD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404325	25893251	AMD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404325	25893251	AMD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404325	25893251	CLM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404325	25893251	CLM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404325	25893251	JEF	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404325	25893251	JKM	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404325	25893251	LSO	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404325	25893251	LSO	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404325	25893251	MSH	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404325	25893251	RGS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404325	25893251	RGS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404325	25893251	VK	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5225627	28077077	AW	2	designed the study|conducted field-work|conceived the project and obtained funding	designed the study	Conceived and designed the experiments	Methodology	YES
5225627	28077077	AW	2	designed the study|conducted field-work|conceived the project and obtained funding	conducted field-work	Performed the experiments	Investigation	YES
5225627	28077077	AW	2	designed the study|conducted field-work|conceived the project and obtained funding	conceived the project and obtained funding	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
5225627	28077077	CR	2	designed the study|performed the research and analyzed the data	designed the study	Conceived and designed the experiments	Methodology	YES
5225627	28077077	CR	2	designed the study|performed the research and analyzed the data	performed the research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5225627	28077077	FG	2	conducted field-work	conducted field-work	Performed the experiments	Investigation	YES
5225627	28077077	KKS	2	conceived the project and obtained funding	conceived the project and obtained funding	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
5225627	28077077	MCF	2	designed the study|conducted field-work|performed the research and analyzed the data	designed the study	Conceived and designed the experiments	Methodology	YES
5225627	28077077	MCF	2	designed the study|conducted field-work|performed the research and analyzed the data	conducted field-work	Performed the experiments	Investigation	YES
5225627	28077077	MCF	2	designed the study|conducted field-work|performed the research and analyzed the data	performed the research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5225627	28077077	ML	2	performed the research and analyzed the data	performed the research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5225627	28077077	MR	2	performed the research and analyzed the data	performed the research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5225627	28077077	RH	2	conceived the project and obtained funding	conceived the project and obtained funding	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
4802399	27054034	Claudia Filisetti	7	data collection and writing the paper	data collection and writing the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4802399	27054034	Claudio Vella	7	analysis and interpretation of the data	analysis and interpretation of the data	Analyzed the data	Formal analysis	YES
4802399	27054034	Federica Marinoni	7	data collection and analysis	data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4802399	27054034	Giovanna Riccipetitoni	7	study design and interpretation	study design and interpretation	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
4802399	27054034	Sara Costanzo	7	data collection	data collection	Performed the experiments	Investigation	YES
5419380	28970417	All authors	PLoS52	contributed to study design and prepared the manuscript	contributed to study design and prepared the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5419380	28970417	C.E.	PLoS52	performed the interviews|analyzed the data	performed the interviews	Performed the experiments	Investigation	YES
5419380	28970417	C.E.	PLoS52	performed the interviews|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5419380	28970417	G.G.	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5419380	28970417	all authors	PLoS52	critically revised, contributed with comments, and approved the final version of the manuscript	critically revised, contributed with comments, and approved the final version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4949199	27430576	All authors	2	contributed to the concept and design of the study|provided critical revision|read and approved the final manuscript	contributed to the concept and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4949199	27430576	All authors	2	contributed to the concept and design of the study|provided critical revision|read and approved the final manuscript	provided critical revision	Wrote the paper	Writing - Review & Editing	YES
4949199	27430576	All authors	2	contributed to the concept and design of the study|provided critical revision|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4949199	27430576	BH	2	contributed in the analyses and interpretation of the data and in the drafting of the manuscript	contributed in the analyses and interpretation of the data and in the drafting of the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
4949199	27430576	SB	2	contributed in the analyses and interpretation of the data and in the drafting of the manuscript	contributed in the analyses and interpretation of the data and in the drafting of the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
5514348	28769974	JT	PLoS52	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5514348	28769974	JZ	PLoS52	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5514348	28769974	QC	PLoS52	performed research|wrote the paper	performed research	Performed the experiments	Investigation	YES
5514348	28769974	QC	PLoS52	performed research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5514348	28769974	RL	PLoS52	designed research|performed research	designed research	Conceived and designed the experiments	Methodology	YES
5514348	28769974	RL	PLoS52	designed research|performed research	performed research	Performed the experiments	Investigation	YES
5514348	28769974	SH	PLoS52	analyzed data|wrote the paper	analyzed data	Analyzed the data	Formal analysis	YES
5514348	28769974	SH	PLoS52	analyzed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5514348	28769974	YB	PLoS52	performed research|analyzed data|wrote the paper	performed research	Performed the experiments	Investigation	YES
5514348	28769974	YB	PLoS52	performed research|analyzed data|wrote the paper	analyzed data	Analyzed the data	Formal analysis	YES
5514348	28769974	YB	PLoS52	performed research|analyzed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5514348	28769974	YL	PLoS52	designed research|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
5514348	28769974	YL	PLoS52	designed research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5514348	28769974	YY	PLoS52	designed research|analyzed data|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
5514348	28769974	YY	PLoS52	designed research|analyzed data|wrote the paper	analyzed data	Analyzed the data	Formal analysis	YES
5514348	28769974	YY	PLoS52	designed research|analyzed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5552266	28780078	A.K.	2	conceived and designed the experiments and prepared the manuscript	conceived and designed the experiments and prepared the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
5552266	28780078	All authors	2	discussed the results and commented on the manuscript	discussed the results and commented on the manuscript	-	-	NO
5552266	28780078	H.I.	2	helped with imaging of the ateam stable pc12 cell line	helped with imaging of the ateam stable pc12 cell line	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
5552266	28780078	M.N.	2	conceived and designed the experiments and prepared the manuscript|conducted and analyzed the majority of both the cell and the animal experiments	conceived and designed the experiments and prepared the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
5552266	28780078	M.N.	2	conceived and designed the experiments and prepared the manuscript|conducted and analyzed the majority of both the cell and the animal experiments	conducted and analyzed the majority of both the cell and the animal experiments	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5552266	28780078	M.Y.	2	helped with imaging of brain sections of go-ateam2 mice	helped with imaging of brain sections of go-ateam2 mice	Analyzed the data	Visualization	YES
5552266	28780078	N.S.	2	performed rt qpcr	performed rt qpcr	Performed the experiments	Investigation	YES
5552266	28780078	T.F.	2	synthesized kus compounds	synthesized kus compounds	Performed the experiments	Investigation	YES
5552266	28780078	T.S.	2	synthesized kus compounds	synthesized kus compounds	Performed the experiments	Investigation	YES
5109784	27895697	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5109784	27895697	CG	2	contributed to data mining and cleaning	contributed to data mining and cleaning	Analyzed the data	Data curation|Formal analysis	YES
5109784	27895697	EMO	2	developed the protocol|reviewed and revised the manuscript	developed the protocol	Conceived and designed the experiments	Methodology	YES
5109784	27895697	EMO	2	developed the protocol|reviewed and revised the manuscript	reviewed and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5109784	27895697	ENK	2	interpreted the data|prepared the draft manuscript|reviewed and revised the manuscript	interpreted the data	Analyzed the data	Formal analysis	YES
5109784	27895697	ENK	2	interpreted the data|prepared the draft manuscript|reviewed and revised the manuscript	prepared the draft manuscript	Wrote the paper	Writing - Original Draft	YES
5109784	27895697	ENK	2	interpreted the data|prepared the draft manuscript|reviewed and revised the manuscript	reviewed and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5109784	27895697	Gladys W. Omondi	2	for assistance provided in formatting the manuscript	for assistance provided in formatting the manuscript	-	-	NO
5109784	27895697	IM	2	prepared the draft manuscript	prepared the draft manuscript	Wrote the paper	Writing - Original Draft	YES
5109784	27895697	JJO	2	prepared the draft manuscript	prepared the draft manuscript	Wrote the paper	Writing - Original Draft	YES
5109784	27895697	JOM	2	developed the protocol|contributed to the conception of the analysis idea|interpreted the data|prepared the draft manuscript|reviewed and revised the manuscript	developed the protocol	Conceived and designed the experiments	Methodology	YES
5109784	27895697	JOM	2	developed the protocol|contributed to the conception of the analysis idea|interpreted the data|prepared the draft manuscript|reviewed and revised the manuscript	contributed to the conception of the analysis idea	Conceived and designed the experiments	Conceptualization	YES
5109784	27895697	JOM	2	developed the protocol|contributed to the conception of the analysis idea|interpreted the data|prepared the draft manuscript|reviewed and revised the manuscript	interpreted the data	Analyzed the data	Formal analysis	YES
5109784	27895697	JOM	2	developed the protocol|contributed to the conception of the analysis idea|interpreted the data|prepared the draft manuscript|reviewed and revised the manuscript	prepared the draft manuscript	Wrote the paper	Writing - Original Draft	YES
5109784	27895697	JOM	2	developed the protocol|contributed to the conception of the analysis idea|interpreted the data|prepared the draft manuscript|reviewed and revised the manuscript	reviewed and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5109784	27895697	LNN	2	prepared the draft manuscript	prepared the draft manuscript	Wrote the paper	Writing - Original Draft	YES
5109784	27895697	LWN	2	contributed to the conception of the analysis idea|conducted the analyses|interpreted the data|prepared the draft manuscript	contributed to the conception of the analysis idea	Conceived and designed the experiments	Conceptualization	YES
5109784	27895697	LWN	2	contributed to the conception of the analysis idea|conducted the analyses|interpreted the data|prepared the draft manuscript	conducted the analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5109784	27895697	LWN	2	contributed to the conception of the analysis idea|conducted the analyses|interpreted the data|prepared the draft manuscript	interpreted the data	Analyzed the data	Formal analysis	YES
5109784	27895697	LWN	2	contributed to the conception of the analysis idea|conducted the analyses|interpreted the data|prepared the draft manuscript	prepared the draft manuscript	Wrote the paper	Writing - Original Draft	YES
5109784	27895697	MW	2	contributed to data mining and cleaning	contributed to data mining and cleaning	Analyzed the data	Data curation|Formal analysis	YES
5109784	27895697	NK	2	prepared the draft manuscript	prepared the draft manuscript	Wrote the paper	Writing - Original Draft	YES
5109784	27895697	PNM	2	reviewed and revised the manuscript	reviewed and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5109784	27895697	RN	2	contributed to data mining and cleaning	contributed to data mining and cleaning	Analyzed the data	Data curation|Formal analysis	YES
5109784	27895697	SI	2	prepared the draft manuscript	prepared the draft manuscript	Wrote the paper	Writing - Original Draft	YES
5109784	27895697	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5109784	27895697	ZN	2	reviewed and revised the manuscript	reviewed and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4545195	26297538	AU	2	performed the sequencing and participated in sequence alignment	performed the sequencing and participated in sequence alignment	Performed the experiments	Investigation	YES
4545195	26297538	KM	2	reviewed the statistics, participated in the patient recruitment, collected the clinical data and reviewed the final version of the manuscript	reviewed the statistics, participated in the patient recruitment, collected the clinical data and reviewed the final version of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
4545195	26297538	MLP	2	reviewed the statistics, participated in the patient recruitment, collected the clinical data and reviewed the final version of the manuscript	reviewed the statistics, participated in the patient recruitment, collected the clinical data and reviewed the final version of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
4545195	26297538	MP	2	designed the study, performed sequence alignment and phylogenetic analyses, drafted the figures and prepared the manuscript	designed the study, performed sequence alignment and phylogenetic analyses, drafted the figures and prepared the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Visualization|Writing - Original Draft	YES
4545195	26297538	MWJ	2	reviewed the statistics, participated in the patient recruitment, collected the clinical data and reviewed the final version of the manuscript	reviewed the statistics, participated in the patient recruitment, collected the clinical data and reviewed the final version of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
4545195	26297538	SM	2	reviewed the statistics, collected the clinical data and reviewed the final version of the manuscript	reviewed the statistics, collected the clinical data and reviewed the final version of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
4802407	27054031	Akio Kanda	PLoS52	assisted the surgery	assisted the surgery	Performed the experiments	Investigation	YES
4802407	27054031	All authors	PLoS52	have contributed significantly, and that all authors are in agreement with the content of the manuscript	have contributed significantly, and that all authors are in agreement with the content of the manuscript	-	-	NO
4802407	27054031	Atsuhiko Mogami	PLoS52	assisted the surgery	assisted the surgery	Performed the experiments	Investigation	YES
4802407	27054031	Hiroyuki Obata	PLoS52	assisted the surgery	assisted the surgery	Performed the experiments	Investigation	YES
4802407	27054031	Itaru Morohashi	PLoS52	wrote the paper|operated the patient	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4802407	27054031	Itaru Morohashi	PLoS52	wrote the paper|operated the patient	operated the patient	Performed the experiments	Investigation	YES
4802407	27054031	Kaneko Kazuo	PLoS52	performed the manuscript editing	performed the manuscript editing	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4802407	27054031	Osamu Obayashi	PLoS52	performed the manuscript editing	performed the manuscript editing	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4802407	27054031	Yasuhiro Homma	PLoS52	wrote the paper|performed the manuscript editing	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4802407	27054031	Yasuhiro Homma	PLoS52	wrote the paper|performed the manuscript editing	performed the manuscript editing	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4802407	27054031	Yasuhiro Yamamoto	PLoS52	assisted the surgery	assisted the surgery	Performed the experiments	Investigation	YES
4404326	25893439	CH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404326	25893439	CH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404326	25893439	CH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404326	25893439	CMB	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404326	25893439	JC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4404326	25893439	JUI	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404326	25893439	MY	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4404326	25893439	PZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4404326	25893439	QZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4404326	25893439	SL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404326	25893439	SL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404326	25893439	SL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404326	25893439	SL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404326	25893439	WS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404326	25893439	WS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404326	25893439	WS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404326	25893439	XH	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4404326	25893439	XH	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404326	25893439	YL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404326	25893439	YL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404326	25893439	YL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404326	25893439	ZW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5111210	27891161	AS	2	participated in the conception and design of the manuscript	participated in the conception and design of the manuscript	Conceived and designed the experiments	Conceptualization	YES
5111210	27891161	AU	2	participated in the conception and design of the manuscript	participated in the conception and design of the manuscript	Conceived and designed the experiments	Conceptualization	YES
5111210	27891161	All authors	2	revised the script critically|read and approved the final manuscript	revised the script critically	Wrote the paper	Writing - Review & Editing	YES
5111210	27891161	All authors	2	revised the script critically|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5111210	27891161	CN	2	participated in the conception and design of the manuscript|performed the statistical analysis and drafted the manuscript	participated in the conception and design of the manuscript	Conceived and designed the experiments	Conceptualization	YES
5111210	27891161	CN	2	participated in the conception and design of the manuscript|performed the statistical analysis and drafted the manuscript	performed the statistical analysis and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5111210	27891161	GM	2	participated in the conception and design of the manuscript	participated in the conception and design of the manuscript	Conceived and designed the experiments	Conceptualization	YES
5111210	27891161	KC	2	participated in the conception and design of the manuscript	participated in the conception and design of the manuscript	Conceived and designed the experiments	Conceptualization	YES
4967068	27473754	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4967068	27473754	DD	2	constructed the electronic database|performed the data analyses	constructed the electronic database	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
4967068	27473754	DD	2	constructed the electronic database|performed the data analyses	performed the data analyses	Analyzed the data	Formal analysis	YES
4967068	27473754	FH	2	constructed the electronic database|performed the data analyses	constructed the electronic database	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
4967068	27473754	FH	2	constructed the electronic database|performed the data analyses	performed the data analyses	Analyzed the data	Formal analysis	YES
4967068	27473754	LY	2	designed the study|constructed the electronic database|performed the data analyses|wrote the first draft of the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
4967068	27473754	LY	2	designed the study|constructed the electronic database|performed the data analyses|wrote the first draft of the manuscript	constructed the electronic database	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
4967068	27473754	LY	2	designed the study|constructed the electronic database|performed the data analyses|wrote the first draft of the manuscript	performed the data analyses	Analyzed the data	Formal analysis	YES
4967068	27473754	LY	2	designed the study|constructed the electronic database|performed the data analyses|wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
4967068	27473754	PWW	2	assessed the patients|performed the data analyses	assessed the patients	-	-	NO
4967068	27473754	PWW	2	assessed the patients|performed the data analyses	performed the data analyses	Analyzed the data	Formal analysis	YES
4967068	27473754	SM	2	designed the study|assessed the patients|performed the data analyses	designed the study	Conceived and designed the experiments	Methodology	YES
4967068	27473754	SM	2	designed the study|assessed the patients|performed the data analyses	assessed the patients	-	-	NO
4967068	27473754	SM	2	designed the study|assessed the patients|performed the data analyses	performed the data analyses	Analyzed the data	Formal analysis	YES
4967068	27473754	SS	2	constructed the electronic database|performed the data analyses	constructed the electronic database	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
4967068	27473754	SS	2	constructed the electronic database|performed the data analyses	performed the data analyses	Analyzed the data	Formal analysis	YES
4967068	27473754	TAK	2	designed the study|assessed the patients	designed the study	Conceived and designed the experiments	Methodology	YES
4967068	27473754	TAK	2	designed the study|assessed the patients	assessed the patients	-	-	NO
522810	15387886	BL	2	provided statistical guidance throughout the project	provided statistical guidance throughout the project	Analyzed the data	Formal analysis|Supervision	YES
522810	15387886	DAS	2	initiated and crafted the idea and provided the necessary mentorship along the way	initiated and crafted the idea and provided the necessary mentorship along the way	Conceived and designed the experiments	Conceptualization|Supervision	YES
522810	15387886	DC	2	provided us with cdna array data and aided in the analysis of the cdna expression data|also provided much appreciated critical input throughout the entire project	provided us with cdna array data and aided in the analysis of the cdna expression data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
522810	15387886	DC	2	provided us with cdna array data and aided in the analysis of the cdna expression data|also provided much appreciated critical input throughout the entire project	also provided much appreciated critical input throughout the entire project	-	-	NO
522810	15387886	KMB	2	participated in the sample preparation and hybridization to arrays of the in-house gene expression data	participated in the sample preparation and hybridization to arrays of the in-house gene expression data	Performed the experiments	Investigation	YES
522810	15387886	MM	2	participated in finding and extracting the public data and aided in drafting the manuscript	participated in finding and extracting the public data and aided in drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
522810	15387886	MMH	2	participated in the sample preparation and hybridization to arrays of the in-house gene expression data|was a tremendous help in editing the final manuscript	participated in the sample preparation and hybridization to arrays of the in-house gene expression data	Performed the experiments	Investigation	YES
522810	15387886	MMH	2	participated in the sample preparation and hybridization to arrays of the in-house gene expression data|was a tremendous help in editing the final manuscript	was a tremendous help in editing the final manuscript	Wrote the paper	Writing - Review & Editing	YES
522810	15387886	SAM	2	carried out the accumulation of datasets, preparation of the predictors, data analysis and drafted the manuscript|also provided essential mentor support	carried out the accumulation of datasets, preparation of the predictors, data analysis and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
522810	15387886	SAM	2	carried out the accumulation of datasets, preparation of the predictors, data analysis and drafted the manuscript|also provided essential mentor support	also provided essential mentor support	-	-	NO
5514350	28769944	EF	7	Collected samples from the field, conducted laboratory work and sequence analysis, revised the manuscript	Collected samples from the field, conducted laboratory work and sequence analysis, revised the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
5514350	28769944	HL-K	7	Conceived funding for the project, designed the work, collected samples from the field, supervised and conducted analysis of sequence data, did data interpretation, drafted and revised the manuscript	Conceived funding for the project, designed the work, collected samples from the field, supervised and conducted analysis of sequence data, did data interpretation, drafted and revised the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Funding acquisition|Investigation|Methodology|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
5514350	28769944	JH	7	Collected samples from the field, conducted laboratory work and pathogenicity assays, conducted sequence analysis, drafted the manuscript	Collected samples from the field, conducted laboratory work and pathogenicity assays, conducted sequence analysis, drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5514350	28769944	JK	7	Conceived funding for the project, designed the work, supervised and conducted analysis of sequence data, did data interpretation, revised the manuscript	Conceived funding for the project, designed the work, supervised and conducted analysis of sequence data, did data interpretation, revised the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Funding acquisition|Investigation|Methodology|Supervision|Writing - Review & Editing	YES
5514350	28769944	LG	7	Collected samples from the field, conducted and supervised the laboratory work, conducted and supervised the pathogenicity assays, drafted and revised the manuscript	Collected samples from the field, conducted and supervised the laboratory work, conducted and supervised the pathogenicity assays, drafted and revised the manuscript	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
5605377	28851583	HL	PLoS52	designed experiments|performed experiments|interpreted data	designed experiments	Conceived and designed the experiments	Methodology	YES
5605377	28851583	HL	PLoS52	designed experiments|performed experiments|interpreted data	performed experiments	Performed the experiments	Investigation	YES
5605377	28851583	HL	PLoS52	designed experiments|performed experiments|interpreted data	interpreted data	Analyzed the data	Formal analysis	YES
5605377	28851583	HT	PLoS52	planned overall concepts|designed experiments|performed experiments|interpreted data|wrote the paper	planned overall concepts	Conceived and designed the experiments	Conceptualization	YES
5605377	28851583	HT	PLoS52	planned overall concepts|designed experiments|performed experiments|interpreted data|wrote the paper	designed experiments	Conceived and designed the experiments	Methodology	YES
5605377	28851583	HT	PLoS52	planned overall concepts|designed experiments|performed experiments|interpreted data|wrote the paper	performed experiments	Performed the experiments	Investigation	YES
5605377	28851583	HT	PLoS52	planned overall concepts|designed experiments|performed experiments|interpreted data|wrote the paper	interpreted data	Analyzed the data	Formal analysis	YES
5605377	28851583	HT	PLoS52	planned overall concepts|designed experiments|performed experiments|interpreted data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5605377	28851583	LB	PLoS52	designed experiments|performed experiments|interpreted data	designed experiments	Conceived and designed the experiments	Methodology	YES
5605377	28851583	LB	PLoS52	designed experiments|performed experiments|interpreted data	performed experiments	Performed the experiments	Investigation	YES
5605377	28851583	LB	PLoS52	designed experiments|performed experiments|interpreted data	interpreted data	Analyzed the data	Formal analysis	YES
5605377	28851583	ML	PLoS52	planned overall concepts|designed experiments|interpreted data|wrote the paper	planned overall concepts	Conceived and designed the experiments	Conceptualization	YES
5605377	28851583	ML	PLoS52	planned overall concepts|designed experiments|interpreted data|wrote the paper	designed experiments	Conceived and designed the experiments	Methodology	YES
5605377	28851583	ML	PLoS52	planned overall concepts|designed experiments|interpreted data|wrote the paper	interpreted data	Analyzed the data	Formal analysis	YES
5605377	28851583	ML	PLoS52	planned overall concepts|designed experiments|interpreted data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5605377	28851583	YW	PLoS52	planned overall concepts|designed experiments|performed experiments|interpreted data|wrote the paper	planned overall concepts	Conceived and designed the experiments	Conceptualization	YES
5605377	28851583	YW	PLoS52	planned overall concepts|designed experiments|performed experiments|interpreted data|wrote the paper	designed experiments	Conceived and designed the experiments	Methodology	YES
5605377	28851583	YW	PLoS52	planned overall concepts|designed experiments|performed experiments|interpreted data|wrote the paper	performed experiments	Performed the experiments	Investigation	YES
5605377	28851583	YW	PLoS52	planned overall concepts|designed experiments|performed experiments|interpreted data|wrote the paper	interpreted data	Analyzed the data	Formal analysis	YES
5605377	28851583	YW	PLoS52	planned overall concepts|designed experiments|performed experiments|interpreted data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4552862	26318960	AM	PLoS52	designed the study and wrote the protocol|designed the patient survey|conducted research at sites|wrote the manuscript	designed the study and wrote the protocol	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4552862	26318960	AM	PLoS52	designed the study and wrote the protocol|designed the patient survey|conducted research at sites|wrote the manuscript	designed the patient survey	Conceived and designed the experiments|Performed the experiments	Investigation	YES
4552862	26318960	AM	PLoS52	designed the study and wrote the protocol|designed the patient survey|conducted research at sites|wrote the manuscript	conducted research at sites	Performed the experiments	Investigation	YES
4552862	26318960	AM	PLoS52	designed the study and wrote the protocol|designed the patient survey|conducted research at sites|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4552862	26318960	DES	PLoS52	designed the study and wrote the protocol|designed the patient survey|conducted research at sites|wrote the manuscript	designed the study and wrote the protocol	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4552862	26318960	DES	PLoS52	designed the study and wrote the protocol|designed the patient survey|conducted research at sites|wrote the manuscript	designed the patient survey	Conceived and designed the experiments|Performed the experiments	Investigation	YES
4552862	26318960	DES	PLoS52	designed the study and wrote the protocol|designed the patient survey|conducted research at sites|wrote the manuscript	conducted research at sites	Performed the experiments	Investigation	YES
4552862	26318960	DES	PLoS52	designed the study and wrote the protocol|designed the patient survey|conducted research at sites|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4552862	26318960	DLC	PLoS52	designed the study and wrote the protocol|designed the patient survey|conducted research at sites|wrote the manuscript	designed the study and wrote the protocol	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4552862	26318960	DLC	PLoS52	designed the study and wrote the protocol|designed the patient survey|conducted research at sites|wrote the manuscript	designed the patient survey	Conceived and designed the experiments|Performed the experiments	Investigation	YES
4552862	26318960	DLC	PLoS52	designed the study and wrote the protocol|designed the patient survey|conducted research at sites|wrote the manuscript	conducted research at sites	Performed the experiments	Investigation	YES
4552862	26318960	DLC	PLoS52	designed the study and wrote the protocol|designed the patient survey|conducted research at sites|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4552862	26318960	DPC	PLoS52	designed the study and wrote the protocol|designed the patient survey|coordinated the project|were in charge of staff training and quality management|analyzed the data|wrote the manuscript	designed the study and wrote the protocol	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4552862	26318960	DPC	PLoS52	designed the study and wrote the protocol|designed the patient survey|coordinated the project|were in charge of staff training and quality management|analyzed the data|wrote the manuscript	designed the patient survey	Conceived and designed the experiments|Performed the experiments	Investigation	YES
4552862	26318960	DPC	PLoS52	designed the study and wrote the protocol|designed the patient survey|coordinated the project|were in charge of staff training and quality management|analyzed the data|wrote the manuscript	coordinated the project	-	Project administration	YES
4552862	26318960	DPC	PLoS52	designed the study and wrote the protocol|designed the patient survey|coordinated the project|were in charge of staff training and quality management|analyzed the data|wrote the manuscript	were in charge of staff training and quality management	-	-	NO
4552862	26318960	DPC	PLoS52	designed the study and wrote the protocol|designed the patient survey|coordinated the project|were in charge of staff training and quality management|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
4552862	26318960	DPC	PLoS52	designed the study and wrote the protocol|designed the patient survey|coordinated the project|were in charge of staff training and quality management|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4552862	26318960	MH	PLoS52	designed the study and wrote the protocol|designed the patient survey|analyzed the data|wrote the manuscript	designed the study and wrote the protocol	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4552862	26318960	MH	PLoS52	designed the study and wrote the protocol|designed the patient survey|analyzed the data|wrote the manuscript	designed the patient survey	Conceived and designed the experiments|Performed the experiments	Investigation	YES
4552862	26318960	MH	PLoS52	designed the study and wrote the protocol|designed the patient survey|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
4552862	26318960	MH	PLoS52	designed the study and wrote the protocol|designed the patient survey|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4552862	26318960	PC	PLoS52	designed the study and wrote the protocol|were in charge of staff training and quality management|wrote the manuscript	designed the study and wrote the protocol	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4552862	26318960	PC	PLoS52	designed the study and wrote the protocol|were in charge of staff training and quality management|wrote the manuscript	were in charge of staff training and quality management	-	-	NO
4552862	26318960	PC	PLoS52	designed the study and wrote the protocol|were in charge of staff training and quality management|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4552862	26318960	PK	PLoS52	designed the study and wrote the protocol|designed the patient survey|coordinated the project|wrote the manuscript	designed the study and wrote the protocol	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4552862	26318960	PK	PLoS52	designed the study and wrote the protocol|designed the patient survey|coordinated the project|wrote the manuscript	designed the patient survey	Conceived and designed the experiments|Performed the experiments	Investigation	YES
4552862	26318960	PK	PLoS52	designed the study and wrote the protocol|designed the patient survey|coordinated the project|wrote the manuscript	coordinated the project	-	Project administration	YES
4552862	26318960	PK	PLoS52	designed the study and wrote the protocol|designed the patient survey|coordinated the project|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4552862	26318960	RG	PLoS52	designed the study and wrote the protocol|designed the patient survey|coordinated the project|analyzed the data|wrote the manuscript	designed the study and wrote the protocol	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4552862	26318960	RG	PLoS52	designed the study and wrote the protocol|designed the patient survey|coordinated the project|analyzed the data|wrote the manuscript	designed the patient survey	Conceived and designed the experiments|Performed the experiments	Investigation	YES
4552862	26318960	RG	PLoS52	designed the study and wrote the protocol|designed the patient survey|coordinated the project|analyzed the data|wrote the manuscript	coordinated the project	-	Project administration	YES
4552862	26318960	RG	PLoS52	designed the study and wrote the protocol|designed the patient survey|coordinated the project|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
4552862	26318960	RG	PLoS52	designed the study and wrote the protocol|designed the patient survey|coordinated the project|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4552862	26318960	SCD	PLoS52	designed the study and wrote the protocol|designed the patient survey|conducted research at sites|wrote the manuscript	designed the study and wrote the protocol	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4552862	26318960	SCD	PLoS52	designed the study and wrote the protocol|designed the patient survey|conducted research at sites|wrote the manuscript	designed the patient survey	Conceived and designed the experiments|Performed the experiments	Investigation	YES
4552862	26318960	SCD	PLoS52	designed the study and wrote the protocol|designed the patient survey|conducted research at sites|wrote the manuscript	conducted research at sites	Performed the experiments	Investigation	YES
4552862	26318960	SCD	PLoS52	designed the study and wrote the protocol|designed the patient survey|conducted research at sites|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4404327	25894340	HY	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404327	25894340	HZ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404327	25894340	JA	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404327	25894340	JX	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404327	25894340	SW	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404327	25894340	SW	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404327	25894340	XY	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4404327	25894340	XY	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404327	25894340	XZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4404327	25894340	YC	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404327	25894340	YC	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404327	25894340	YW	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404327	25894340	YW	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5419384	28970427	All authors	2	interpreted the data and drafted the manuscript	interpreted the data and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5419384	28970427	Joshua D. Brown	2	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5419384	28970427	Nathan J. Pauly	2	performed the data analysis	performed the data analysis	Analyzed the data	Formal analysis	YES
4816900	27076910	K Walsh	7	Article proof-reading	Article proof-reading	-	-	NO
4816900	27076910	Nikhil Sharma	7	Audit conception and proposal, study design, data-collection, data-analysis, presentation and write-up. Aideen	Audit conception and proposal, study design, data-collection, data-analysis, presentation and write-up. Aideen	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology	YES
4816900	27076910	Siriram Rajagopalan	7	Study-design, data-analysis and proof-reading	Study-design, data-analysis and proof-reading	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
4987743	27530736	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4987743	27530736	EQ	2	participated in the study design and revised the article	participated in the study design and revised the article	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
4987743	27530736	ESS	2	contributed to the study design, collected the data, analyzed and interpreted the data, and drafted the article	contributed to the study design, collected the data, analyzed and interpreted the data, and drafted the article	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
4987743	27530736	JF	2	was involved in interpreting the data, and reworked the article	was involved in interpreting the data, and reworked the article	Performed the experiments|Analyzed the data	Formal analysis	YES
4987743	27530736	MA	2	revised the article	revised the article	Wrote the paper	Writing - Review & Editing	YES
4987743	27530736	PH	2	collected the data and revised the article	collected the data and revised the article	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4987743	27530736	TJS	2	contributed to the study design, supervised all procedures and revised the article	contributed to the study design, supervised all procedures and revised the article	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Supervision|Writing - Review & Editing	YES
5124249	27906032	AIDS	2	at case western reserve university	at case western reserve university	-	-	NO
5124249	27906032	All	2	the shivenv viruses produced in the present study are available upon request	the shivenv viruses produced in the present study are available upon request	-	-	NO
5124249	27906032	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5124249	27906032	BL	2	designed and performed macaque study	designed and performed macaque study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5124249	27906032	EJA	2	provided overall supervision for the project, secured funding, and helped the writing the manuscript	provided overall supervision for the project, secured funding, and helped the writing the manuscript	Wrote the paper	Funding acquisition|Supervision|Writing - Original Draft	YES
5124249	27906032	KCK	2	designed the study, performed the experiments and drafted the manuscript	designed the study, performed the experiments and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5124249	27906032	KH	2	performed various vector construction, virus generation and propagation	performed various vector construction, virus generation and propagation	Performed the experiments	Investigation	YES
5124249	27906032	KN	2	performed various vector construction, virus generation and propagation	performed various vector construction, virus generation and propagation	Performed the experiments	Investigation	YES
5124249	27906032	MA	2	designed and performed macaque study	designed and performed macaque study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5124249	27906032	MT	2	designed the study, performed the experiments and drafted the manuscript	designed the study, performed the experiments and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5124249	27906032	NL	2	provided overall supervision for the project, secured funding, and helped the writing the manuscript	provided overall supervision for the project, secured funding, and helped the writing the manuscript	Wrote the paper	Funding acquisition|Supervision|Writing - Original Draft	YES
5124249	27906032	RG	2	performed various vector construction, virus generation and propagation	performed various vector construction, virus generation and propagation	Performed the experiments	Investigation	YES
5124249	27906032	RJS	2	provided some suggestions for the project and helped the writing of the manuscript	provided some suggestions for the project and helped the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5124249	27906032	RSV	2	designed and performed macaque study	designed and performed macaque study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5124249	27906032	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5124249	27906032	WH	2	performed various vector construction, virus generation and propagation	performed various vector construction, virus generation and propagation	Performed the experiments	Investigation	YES
5124249	27906032	YG	2	designed the study, performed the experiments and drafted the manuscript|provided overall supervision for the project, secured funding, and helped the writing the manuscript	designed the study, performed the experiments and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5124249	27906032	YG	2	designed the study, performed the experiments and drafted the manuscript|provided overall supervision for the project, secured funding, and helped the writing the manuscript	provided overall supervision for the project, secured funding, and helped the writing the manuscript	Wrote the paper	Funding acquisition|Supervision|Writing - Original Draft	YES
5124249	27906032	YL	2	performed various vector construction, virus generation and propagation	performed various vector construction, virus generation and propagation	Performed the experiments	Investigation	YES
5605380	28826655	Diabetes Study Group	2	collected samples	collected samples	Performed the experiments	Investigation	YES
5605380	28826655	KH	2	designed this study|performed the genotyping and statistical analysis	designed this study	Conceived and designed the experiments	Methodology	YES
5605380	28826655	KH	2	designed this study|performed the genotyping and statistical analysis	performed the genotyping and statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5605380	28826655	KM	2	designed this study|wrote this manuscript|performed the genotyping and statistical analysis	designed this study	Conceived and designed the experiments	Methodology	YES
5605380	28826655	KM	2	designed this study|wrote this manuscript|performed the genotyping and statistical analysis	wrote this manuscript	Wrote the paper	Writing - Original Draft	YES
5605380	28826655	KM	2	designed this study|wrote this manuscript|performed the genotyping and statistical analysis	performed the genotyping and statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5605380	28826655	SN	2	designed this study|wrote this manuscript	designed this study	Conceived and designed the experiments	Methodology	YES
5605380	28826655	SN	2	designed this study|wrote this manuscript	wrote this manuscript	Wrote the paper	Writing - Original Draft	YES
5605380	28826655	YH	2	performed the genotyping and statistical analysis	performed the genotyping and statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5605380	28826655	YY	2	wrote this manuscript	wrote this manuscript	Wrote the paper	Writing - Original Draft	YES
5234130	28086783	LKN	2	performed the experiments and analyzed data|wrote the manuscript	performed the experiments and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5234130	28086783	LKN	2	performed the experiments and analyzed data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5234130	28086783	RSS	2	designed the study|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5234130	28086783	RSS	2	designed the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5234130	28086783	SPS	2	designed the study|performed the experiments and analyzed data|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5234130	28086783	SPS	2	designed the study|performed the experiments and analyzed data|wrote the manuscript	performed the experiments and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5234130	28086783	SPS	2	designed the study|performed the experiments and analyzed data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3664462	23730369	CS	2	carried out the measurements, performed the statistical analysis and wrote the manuscript	carried out the measurements, performed the statistical analysis and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3664462	23730369	RKN	2	designed the study, performed the surgeries, and revised the manuscript	designed the study, performed the surgeries, and revised the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
5515825	28769952	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5515825	28769952	KK	2	contributed to proofreading of this manuscript	contributed to proofreading of this manuscript	-	-	NO
5515825	28769952	LF	2	performed validation experiments	performed validation experiments	Performed the experiments	Investigation|Validation	YES
5515825	28769952	LL	2	designed the experiments and wrote the manuscript|conceived the study and managed the experiments	designed the experiments and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5515825	28769952	LL	2	designed the experiments and wrote the manuscript|conceived the study and managed the experiments	conceived the study and managed the experiments	Conceived and designed the experiments	Conceptualization	YES
5515825	28769952	MM	2	designed the experiments and wrote the manuscript|performed validation experiments	designed the experiments and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5515825	28769952	MM	2	designed the experiments and wrote the manuscript|performed validation experiments	performed validation experiments	Performed the experiments	Investigation|Validation	YES
5515825	28769952	WZ	2	performed validation experiments	performed validation experiments	Performed the experiments	Investigation|Validation	YES
5515825	28769952	XL	2	conceived the study and managed the experiments	conceived the study and managed the experiments	Conceived and designed the experiments	Conceptualization	YES
5515825	28769952	XZ	2	contributed to proofreading of this manuscript	contributed to proofreading of this manuscript	-	-	NO
5515825	28769952	YC	2	performed validation experiments	performed validation experiments	Performed the experiments	Investigation|Validation	YES
5515825	28769952	YW	2	contributed powerful analytical tools	contributed powerful analytical tools	Contributed reagents/materials/analysis tools	Resources	YES
4404328	25893677	HK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404328	25893677	HK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404328	25893677	HK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404328	25893677	KO	PLoS5	Performed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4404328	25893677	KO	PLoS5	Performed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4404328	25893677	MY	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4404328	25893677	NK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404328	25893677	NK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404328	25893677	NK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404328	25893677	NK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404328	25893677	OM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4404328	25893677	YH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4404328	25893677	YT	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4561293	26344017	LD	2	are responsible for planning and execution of the project|is responsible for the analysis of the data and manuscript writing	are responsible for planning and execution of the project	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4561293	26344017	LD	2	are responsible for planning and execution of the project|is responsible for the analysis of the data and manuscript writing	is responsible for the analysis of the data and manuscript writing	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4561293	26344017	LM	2	are responsible for planning and execution of the project	are responsible for planning and execution of the project	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4561293	26344017	NH	2	are responsible for planning and execution of the project	are responsible for planning and execution of the project	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5419385	28970423	Nagashekhara Molugulu	2	guided the data collection procedures	guided the data collection procedures	Performed the experiments	Investigation|Supervision	YES
5419385	28970423	Palanisamy Sivanandy	2	conceived and designed the study and wrote the paper	conceived and designed the study and wrote the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
5419385	28970423	Rajenthina Sagaran	2	participated in the analysis of the data	participated in the analysis of the data	Analyzed the data	Formal analysis	YES
5419385	28970423	Sasikala Chinnappan	2	conceived and designed the study and wrote the paper	conceived and designed the study and wrote the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
4840235	27141301	Justas Kuliavas	2	performed literature search, wrote the draft of the paper	performed literature search, wrote the draft of the paper	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4840235	27141301	Narimantas Evaldas Samalavicius	2	conceptualized and designed the study project	conceptualized and designed the study project	Conceived and designed the experiments	Conceptualization|Methodology	YES
4840235	27141301	Povilas Kavaliauskas	2	performed literature search, collected data, performed statistical analysis, conducted the study, wrote the draft of the paper	performed literature search, collected data, performed statistical analysis, conducted the study, wrote the draft of the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4840235	27141301	Raimundas Lunevicius	2	conceptualized and designed the study, supervised the project, performed literature search, made critical revisions, and made a major contribution writing the final version of the manuscript	conceptualized and designed the study, supervised the project, performed literature search, made critical revisions, and made a major contribution writing the final version of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
4840235	27141301	Rytis Maziukas	2	performed literature search, collected data, conducted the study, wrote the draft of the paper	performed literature search, collected data, conducted the study, wrote the draft of the paper	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5652002	28928014	A.F.C.	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5652002	28928014	C.P.	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5652002	28928014	C.Z.	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5652002	28928014	H.H.X.	PLoS52	conceived and designed the experiments|analyzed the data|wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5652002	28928014	H.H.X.	PLoS52	conceived and designed the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5652002	28928014	H.H.X.	PLoS52	conceived and designed the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5652002	28928014	X.H.D.	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5652002	28928014	X.H.D.	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5652002	28928014	X.T.	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5652002	28928014	Y.L.T.	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5652002	28928014	Y.Y.Z.	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5127046	27906037	Both authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5127046	27906037	SS	2	prepared the original manuscript and contributed to subsequent revisions|prepared the original manuscript and contributed to subsequent revisions	prepared the original manuscript and contributed to subsequent revisions	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5127046	27906037	SS	2	prepared the original manuscript and contributed to subsequent revisions|prepared the original manuscript and contributed to subsequent revisions	prepared the original manuscript and contributed to subsequent revisions	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4995194	27552813	AB	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
4995194	27552813	AD	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
4995194	27552813	AF	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
4995194	27552813	AGP	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
4995194	27552813	AHL	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
4995194	27552813	AHS	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
4995194	27552813	AMPC	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
4995194	27552813	AMS	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
4995194	27552813	AR	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
4995194	27552813	AS	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
4995194	27552813	All authors	2	contributed to and approved the final manuscript|read and approved the final manuscript	contributed to and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4995194	27552813	All authors	2	contributed to and approved the final manuscript|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4995194	27552813	BE	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
4995194	27552813	BL	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
4995194	27552813	BM	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
4995194	27552813	BS	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
4995194	27552813	BV	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
4995194	27552813	CC	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
4995194	27552813	CH	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
4995194	27552813	CL	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
4995194	27552813	COD	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
4995194	27552813	CS	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
4995194	27552813	DHM	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
4995194	27552813	ERL	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
4995194	27552813	ES	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
4995194	27552813	EV	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
4995194	27552813	EYWC	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
4995194	27552813	GK	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
4995194	27552813	GMG	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
4995194	27552813	HH	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
4995194	27552813	JC	2	designed the study|were involved with data collection|were involved in the draft manuscript and initial review	designed the study	Conceived and designed the experiments	Methodology	YES
4995194	27552813	JC	2	designed the study|were involved with data collection|were involved in the draft manuscript and initial review	were involved with data collection	Performed the experiments	Investigation	YES
4995194	27552813	JC	2	designed the study|were involved with data collection|were involved in the draft manuscript and initial review	were involved in the draft manuscript and initial review	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4995194	27552813	JGa	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
4995194	27552813	JGe	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
4995194	27552813	JGi	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
4995194	27552813	JKR	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
4995194	27552813	JV	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
4995194	27552813	KSa	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
4995194	27552813	KSu	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
4995194	27552813	LB	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
4995194	27552813	LT	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
4995194	27552813	MA	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
4995194	27552813	MBa	2	designed the study|were involved in the draft manuscript and initial review	designed the study	Conceived and designed the experiments	Methodology	YES
4995194	27552813	MBa	2	designed the study|were involved in the draft manuscript and initial review	were involved in the draft manuscript and initial review	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4995194	27552813	MBe	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
4995194	27552813	MV	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
4995194	27552813	MZ	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
4995194	27552813	PCW	2	were involved in the draft manuscript and initial review	were involved in the draft manuscript and initial review	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4995194	27552813	PG	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
4995194	27552813	PP	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
4995194	27552813	PR	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
4995194	27552813	PT	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
4995194	27552813	RA	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
4995194	27552813	RB	2	designed the study|were involved with data collection|were involved in the draft manuscript and initial review	designed the study	Conceived and designed the experiments	Methodology	YES
4995194	27552813	RB	2	designed the study|were involved with data collection|were involved in the draft manuscript and initial review	were involved with data collection	Performed the experiments	Investigation	YES
4995194	27552813	RB	2	designed the study|were involved with data collection|were involved in the draft manuscript and initial review	were involved in the draft manuscript and initial review	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4995194	27552813	RD	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
4995194	27552813	REN	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
4995194	27552813	RM	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
4995194	27552813	RWL	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
4995194	27552813	SC	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
4995194	27552813	SD	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
4995194	27552813	SH	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
4995194	27552813	SM	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
4995194	27552813	TG	2	designed the study|provided data analysis|were involved in the draft manuscript and initial review	designed the study	Conceived and designed the experiments	Methodology	YES
4995194	27552813	TG	2	designed the study|provided data analysis|were involved in the draft manuscript and initial review	provided data analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
4995194	27552813	TG	2	designed the study|provided data analysis|were involved in the draft manuscript and initial review	were involved in the draft manuscript and initial review	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4995194	27552813	TN	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
4995194	27552813	UL	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
4995194	27552813	VK	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
4995194	27552813	YB	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
4995194	27552813	YOk	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
4995194	27552813	YOs	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
4995194	27552813	YT	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
4840285	27141303	ED	7	Data analysis/interpretation, approval of article. LS-Data analysis/interpretation, critical revision, approval of article. AP-Critical revision, approval of article. TS-Data analysis/interpretation, critical revision, approval of article. AG-Concept/design, Data analysis/interpretation, drafting article, critical revision, approval of article	Data analysis/interpretation, approval of article. LS-Data analysis/interpretation, critical revision, approval of article. AP-Critical revision, approval of article. TS-Data analysis/interpretation, critical revision, approval of article. AG-Concept/design, Data analysis/interpretation, drafting article, critical revision, approval of article	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
4840285	27141303	JG	7	Data analysis/interpretation, critical revision, approval of article, statistics	Data analysis/interpretation, critical revision, approval of article, statistics	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4840285	27141303	YT	7	Critical revision, approval of article	Critical revision, approval of article	Wrote the paper	Writing - Review & Editing	YES
5652009	28928015	D.I.	2	designed the research|wrote the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
5652009	28928015	D.I.	2	designed the research|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5652009	28928015	G.S.	2	designed the research|performed experiments and analyzed the data|wrote the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
5652009	28928015	G.S.	2	designed the research|performed experiments and analyzed the data|wrote the manuscript	performed experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5652009	28928015	G.S.	2	designed the research|performed experiments and analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5652009	28928015	K.N.	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5652009	28928015	M.Y.	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5652009	28928015	N.S.	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5652009	28928015	S.I.	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5515826	28769965	GG	2	designed the experiments|analyzed and interpreted the data|drafted and revised the paper	designed the experiments	Conceived and designed the experiments	Methodology	YES
5515826	28769965	GG	2	designed the experiments|analyzed and interpreted the data|drafted and revised the paper	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5515826	28769965	GG	2	designed the experiments|analyzed and interpreted the data|drafted and revised the paper	drafted and revised the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5515826	28769965	JL	2	designed the experiments|conducted the experiment|analyzed and interpreted the data|drafted and revised the paper	designed the experiments	Conceived and designed the experiments	Methodology	YES
5515826	28769965	JL	2	designed the experiments|conducted the experiment|analyzed and interpreted the data|drafted and revised the paper	conducted the experiment	Performed the experiments	Investigation	YES
5515826	28769965	JL	2	designed the experiments|conducted the experiment|analyzed and interpreted the data|drafted and revised the paper	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5515826	28769965	JL	2	designed the experiments|conducted the experiment|analyzed and interpreted the data|drafted and revised the paper	drafted and revised the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5515826	28769965	JW	2	conducted the experiment	conducted the experiment	Performed the experiments	Investigation	YES
5515826	28769965	JZ	2	conducted the experiment	conducted the experiment	Performed the experiments	Investigation	YES
5515826	28769965	LH	2	conducted the experiment	conducted the experiment	Performed the experiments	Investigation	YES
5515826	28769965	MY	2	drafted and revised the paper	drafted and revised the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5515826	28769965	OR	2	drafted and revised the paper	drafted and revised the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5515826	28769965	PZ	2	analyzed and interpreted the data	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5515826	28769965	YS	2	conducted the experiment	conducted the experiment	Performed the experiments	Investigation	YES
5234253	28086780	IS-C	2	contributed to the writing of the manuscript|conceived and coordinated the study	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5234253	28086780	IS-C	2	contributed to the writing of the manuscript|conceived and coordinated the study	conceived and coordinated the study	Conceived and designed the experiments	Conceptualization|Project administration	YES
5234253	28086780	JFG	2	cloned zbhaa1 and schaa1 into pgreg506	cloned zbhaa1 and schaa1 into pgreg506	Performed the experiments	Investigation	YES
5234253	28086780	LL	2	cloned zbhaa1 and schaa1 into pgreg506	cloned zbhaa1 and schaa1 into pgreg506	Performed the experiments	Investigation	YES
5234253	28086780	MP	2	contributed to the writing of the manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5234253	28086780	PJD	2	performed the phylogenetic and gene neighbourhood analyses of the haa1 homologues|contributed to the writing of the manuscript	performed the phylogenetic and gene neighbourhood analyses of the haa1 homologues	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5234253	28086780	PJD	2	performed the phylogenetic and gene neighbourhood analyses of the haa1 homologues|contributed to the writing of the manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
4335711	25709806	All authors	2	have given approval to the final version of the manuscript	have given approval to the final version of the manuscript	-	-	NO
4335711	25709806	D.T.C.	2	initiated the project|designed the experiments	initiated the project	Conceived and designed the experiments	Conceptualization	YES
4335711	25709806	D.T.C.	2	initiated the project|designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
4335711	25709806	I.W.	2	helped to interpret the results and carried out characterization of the polymers	helped to interpret the results and carried out characterization of the polymers	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4335711	25709806	J.Y.	2	helped to interpret the results and carried out characterization of the polymers	helped to interpret the results and carried out characterization of the polymers	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4335711	25709806	W.S.	2	conducted tem and helped fluorescence microscope experiments	conducted tem and helped fluorescence microscope experiments	Performed the experiments	Investigation	YES
4335711	25709806	Y.R.	2	helped to interpret the results and carried out characterization of the polymers	helped to interpret the results and carried out characterization of the polymers	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4335711	25709806	Y.Z.	2	designed the experiments|synthesized the polymers, performed the experiments and wrote the paper|helped to interpret the results and carried out characterization of the polymers	designed the experiments	Conceived and designed the experiments	Methodology	YES
4335711	25709806	Y.Z.	2	designed the experiments|synthesized the polymers, performed the experiments and wrote the paper|helped to interpret the results and carried out characterization of the polymers	synthesized the polymers, performed the experiments and wrote the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4335711	25709806	Y.Z.	2	designed the experiments|synthesized the polymers, performed the experiments and wrote the paper|helped to interpret the results and carried out characterization of the polymers	helped to interpret the results and carried out characterization of the polymers	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4571618	26374604	Djeneba Ouedraogo	2	contributed to the acquisition of the data and critically reviewed the manuscript	contributed to the acquisition of the data and critically reviewed the manuscript	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Resources|Writing - Review & Editing	YES
4571618	26374604	Felicien Some	2	contributed to the acquisition of the data and critically reviewed the manuscript	contributed to the acquisition of the data and critically reviewed the manuscript	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Resources|Writing - Review & Editing	YES
4571618	26374604	Issouf Konate	2	contributed to the acquisition of the data and critically reviewed the manuscript	contributed to the acquisition of the data and critically reviewed the manuscript	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Resources|Writing - Review & Editing	YES
4571618	26374604	Josiane Some Anselme	2	contributed to the acquisition of the data and critically reviewed the manuscript	contributed to the acquisition of the data and critically reviewed the manuscript	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Resources|Writing - Review & Editing	YES
4571618	26374604	Nicolas Meda	2	contributed to designing the study, interpretation of the data and critically reviewed the manuscript	contributed to designing the study, interpretation of the data and critically reviewed the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Review & Editing	YES
4571618	26374604	Nicolas Nagot	2	contributed to designing the study, and the acquisition, analysis and interpretation of the data|also wrote the manuscript and supervised its development	contributed to designing the study, and the acquisition, analysis and interpretation of the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Methodology|Resources	YES
4571618	26374604	Nicolas Nagot	2	contributed to designing the study, and the acquisition, analysis and interpretation of the data|also wrote the manuscript and supervised its development	also wrote the manuscript and supervised its development	Wrote the paper	Supervision|Writing - Original Draft	YES
4571618	26374604	Noelie M. Hema	2	contributed to the acquisition of the data and critically reviewed the manuscript	contributed to the acquisition of the data and critically reviewed the manuscript	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Resources|Writing - Review & Editing	YES
4571618	26374604	Philippe Mayaud	2	contributed to designing the study, interpretation of the data and critically reviewed the manuscript	contributed to designing the study, interpretation of the data and critically reviewed the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Review & Editing	YES
4571618	26374604	Philippe Van De	2	contributed to designing the study, interpretation of the data and critically reviewed the manuscript	contributed to designing the study, interpretation of the data and critically reviewed the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Review & Editing	YES
4571618	26374604	Roselyne Some	2	contributed to the acquisition of the data and critically reviewed the manuscript	contributed to the acquisition of the data and critically reviewed the manuscript	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Resources|Writing - Review & Editing	YES
4571618	26374604	T Traore	2	contributed to designing the study, and the acquisition, analysis and interpretation of the data|also wrote the draft manuscript	contributed to designing the study, and the acquisition, analysis and interpretation of the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Methodology|Resources	YES
4571618	26374604	T Traore	2	contributed to designing the study, and the acquisition, analysis and interpretation of the data|also wrote the draft manuscript	also wrote the draft manuscript	Wrote the paper	Writing - Original Draft	YES
4404330	25893845	CF	PLoS5	Wrote the paper|Designed the software	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404330	25893845	CF	PLoS5	Wrote the paper|Designed the software	Designed the software	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
4404330	25893845	EL	PLoS5	Conceived and designed the experiments|Provided molecular genetics expertise	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404330	25893845	EL	PLoS5	Conceived and designed the experiments|Provided molecular genetics expertise	Provided molecular genetics expertise	Performed the experiments	Investigation	YES
4404330	25893845	GM	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404330	25893845	GM	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4404330	25893845	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Designed the software	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404330	25893845	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Designed the software	Performed the experiments	Performed the experiments	Investigation	YES
4404330	25893845	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Designed the software	Analyzed the data	Analyzed the data	Formal analysis	YES
4404330	25893845	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Designed the software	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404330	25893845	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Designed the software	Designed the software	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
4404330	25893845	MS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4404330	25893845	MS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4404330	25893845	ST	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404330	25893845	ST	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5419387	28970418	MRPP	2	university team had input into shaping the delivery of the service and its evaluation	university team had input into shaping the delivery of the service and its evaluation	-	-	NO
4840287	27141302	Ikuro Sato	7	pathological diagnosis including molecular techniques	pathological diagnosis including molecular techniques	Performed the experiments	Investigation	YES
4840287	27141302	Jiro Abe	7	patient management including performing surgical operation; writing the paper as a corresponding author	patient management including performing surgical operation; writing the paper as a corresponding author	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4840287	27141302	Ryota Tanaka	7	patient management and performing operation	patient management and performing operation	Performed the experiments	Investigation	YES
4840287	27141302	Satomi Takahashi	7	patient management; supervisor	patient management; supervisor	-	Supervision	YES
4840287	27141302	Shigemi Ito	7	pathological diagnosis and participated in discussion	pathological diagnosis and participated in discussion	Performed the experiments	Investigation	YES
4840287	27141302	Taku Sato	7	patient management and performing operation	patient management and performing operation	Performed the experiments	Investigation	YES
4840287	27141302	Toshimasa Okazaki	7	patient management and performing operation	patient management and performing operation	Performed the experiments	Investigation	YES
5237184	28086981	FO	PLoS5	Script support	Script support	-	-	NO
5237184	28086981	MW	PLoS5	Conceived and designed the study|Analyzed the data	Conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5237184	28086981	MW	PLoS5	Conceived and designed the study|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5237184	28086981	NO	PLoS5	Script support	Script support	-	-	NO
5237184	28086981	NP	PLoS5	Conceived and designed the study|Performed the study|Analyzed the data	Conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5237184	28086981	NP	PLoS5	Conceived and designed the study|Performed the study|Analyzed the data	Performed the study	Performed the experiments	Investigation	YES
5237184	28086981	NP	PLoS5	Conceived and designed the study|Performed the study|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5237184	28086981	TM	PLoS5	Conceived and designed the study|Analyzed the data	Conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5237184	28086981	TM	PLoS5	Conceived and designed the study|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4840289	27141304	DO	7	primary author and researcher|secondary author	primary author and researcher	Wrote the paper	Writing - Original Draft	YES
4840289	27141304	DO	7	primary author and researcher|secondary author	secondary author	-	-	NO
4840289	27141304	Gaurav Chand	7	primary author and researcher	primary author and researcher	Wrote the paper	Writing - Original Draft	YES
4840289	27141304	Kumar Sanam	7	secondary author	secondary author	-	-	NO
4840289	27141304	MD	7	secondary author|secondary author|secondary author	secondary author	-	-	NO
4840289	27141304	MD	7	secondary author|secondary author|secondary author	secondary author	-	-	NO
4840289	27141304	MD	7	secondary author|secondary author|secondary author	secondary author	-	-	NO
4840289	27141304	Patrick Alexander	7	secondary author	secondary author	-	-	NO
4840289	27141304	Prabhat Sinha	7	secondary author	secondary author	-	-	NO
4840289	27141304	Ruby Jhaj	7	secondary author	secondary author	-	-	NO
4404331	25893667	HH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4404331	25893667	HH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4404331	25893667	HH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404331	25893667	HM	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404331	25893667	HT	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404331	25893667	NY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404331	25893667	NY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404331	25893667	NY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404331	25893667	NY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404331	25893667	NY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404331	25893667	TW	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4404331	25893667	TW	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4404331	25893667	TW	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404331	25893667	TY	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4404331	25893667	TY	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4404331	25893667	TY	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404331	25893667	YT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404331	25893667	YT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404331	25893667	YT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404331	25893667	YT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404331	25893667	YT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4575411	26385854	All authors	2	subsequently provided feedback on the manuscript and approved the final submission	subsequently provided feedback on the manuscript and approved the final submission	-	-	NO
4575411	26385854	JMH	2	conducted, recorded and transcribed the provider interviews, and she was responsible for the principle data analysis and writing the manuscript	conducted, recorded and transcribed the provider interviews, and she was responsible for the principle data analysis and writing the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft	YES
4575411	26385854	RCP	2	designed the study and data collection tools, provided mentorship for this project and helped to conduct the principle data analysis and writing of the manuscript	designed the study and data collection tools, provided mentorship for this project and helped to conduct the principle data analysis and writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Supervision|Writing - Original Draft	YES
5652023	28888925	CH	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
5652023	28888925	CH	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5652023	28888925	DPM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5652023	28888925	DPM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
5652023	28888925	DPM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5652023	28888925	DPM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5652023	28888925	IT	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5652023	28888925	JL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5652023	28888925	JL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5652023	28888925	JL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5652023	28888925	JL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5652023	28888925	ML	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5652023	28888925	MPN	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
5652023	28888925	MPN	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5652023	28888925	PH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5652023	28888925	SM	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
5652023	28888925	SM	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5237128	28086873	All authors	2	read, edited and approved the final manuscript	read, edited and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5237128	28086873	GW	2	analyzed data, qpcr validation and drafted the manuscript	analyzed data, qpcr validation and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Validation|Writing - Original Draft	YES
5237128	28086873	GX	2	assisted in animal experiment design and sample collection	assisted in animal experiment design and sample collection	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5237128	28086873	LL	2	participated in the development of the experimental design and assisted in data analysis	participated in the development of the experimental design and assisted in data analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5237128	28086873	NY	2	participated in the experiment design	participated in the experiment design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5237128	28086873	XL	2	assisted in data analysis and pcr validation|provided the concepts of the study, and revised the manuscript	assisted in data analysis and pcr validation	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Validation	YES
5237128	28086873	XL	2	assisted in data analysis and pcr validation|provided the concepts of the study, and revised the manuscript	provided the concepts of the study, and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5237128	28086873	YQ	2	carried out animal inoculation and sample collection	carried out animal inoculation and sample collection	Performed the experiments	Investigation	YES
4840393	27144006	Critical Revision	7	Shah, Newton, Maykel, Samy, Jabir, Steele	Shah, Newton, Maykel, Samy, Jabir, Steele	-	-	NO
4840393	27144006	Statistical Analysis	7	Steele, Zwintscher. Writing of the Manuscript: Steele, Salgar, Zwintscher	Steele, Zwintscher. Writing of the Manuscript: Steele, Salgar, Zwintscher	Wrote the paper	Writing - Original Draft	YES
5515834	28769960	CD	PLoS52	performed the rna isolation and qrt-pcr experiments	performed the rna isolation and qrt-pcr experiments	Performed the experiments	Investigation	YES
5515834	28769960	DZ	PLoS52	performed the rna isolation and qrt-pcr experiments	performed the rna isolation and qrt-pcr experiments	Performed the experiments	Investigation	YES
5515834	28769960	GL	PLoS52	performed the rna isolation and qrt-pcr experiments	performed the rna isolation and qrt-pcr experiments	Performed the experiments	Investigation	YES
5515834	28769960	HY	PLoS52	conceived and designed the experiments|performed the data analysis and wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5515834	28769960	HY	PLoS52	conceived and designed the experiments|performed the data analysis and wrote the manuscript	performed the data analysis and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5515834	28769960	HZ	PLoS52	performed the rna isolation and qrt-pcr experiments	performed the rna isolation and qrt-pcr experiments	Performed the experiments	Investigation	YES
5515834	28769960	JJ	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5515834	28769960	JL	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5515834	28769960	SW	PLoS52	performed the rna isolation and qrt-pcr experiments	performed the rna isolation and qrt-pcr experiments	Performed the experiments	Investigation	YES
5515834	28769960	TZ	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5515834	28769960	XC	PLoS52	performed the rna isolation and qrt-pcr experiments	performed the rna isolation and qrt-pcr experiments	Performed the experiments	Investigation	YES
5515834	28769960	XX	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404332	25894528	DADS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Contributed to discussions of the data and edited the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404332	25894528	DADS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Contributed to discussions of the data and edited the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4404332	25894528	DADS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Contributed to discussions of the data and edited the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4404332	25894528	DADS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Contributed to discussions of the data and edited the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404332	25894528	DADS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Contributed to discussions of the data and edited the manuscript	Contributed to discussions of the data and edited the manuscript	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Review & Editing	YES
4404332	25894528	DDJ	PLoS5	Contributed reagents/materials/analysis tools|Contributed to discussions of the data and edited the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404332	25894528	DDJ	PLoS5	Contributed reagents/materials/analysis tools|Contributed to discussions of the data and edited the manuscript	Contributed to discussions of the data and edited the manuscript	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Review & Editing	YES
4404332	25894528	GVA	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Contributed to discussions of the data and edited the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404332	25894528	GVA	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Contributed to discussions of the data and edited the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404332	25894528	GVA	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Contributed to discussions of the data and edited the manuscript	Contributed to discussions of the data and edited the manuscript	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Review & Editing	YES
4404332	25894528	LSG	PLoS5	Contributed reagents/materials/analysis tools|Contributed to discussions of the data and edited the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404332	25894528	LSG	PLoS5	Contributed reagents/materials/analysis tools|Contributed to discussions of the data and edited the manuscript	Contributed to discussions of the data and edited the manuscript	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Review & Editing	YES
4404332	25894528	OK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Contributed to discussions of the data and edited the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404332	25894528	OK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Contributed to discussions of the data and edited the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404332	25894528	OK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Contributed to discussions of the data and edited the manuscript	Contributed to discussions of the data and edited the manuscript	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Review & Editing	YES
4404332	25894528	TMF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to discussions of the data and edited the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404332	25894528	TMF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to discussions of the data and edited the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4404332	25894528	TMF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to discussions of the data and edited the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404332	25894528	TMF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to discussions of the data and edited the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404332	25894528	TMF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to discussions of the data and edited the manuscript	Contributed to discussions of the data and edited the manuscript	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Review & Editing	YES
4404332	25894528	YW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed to discussions of the data and edited the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404332	25894528	YW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed to discussions of the data and edited the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4404332	25894528	YW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed to discussions of the data and edited the manuscript	Contributed to discussions of the data and edited the manuscript	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Review & Editing	YES
5237283	28086929	AB	2	designed and conducted this sub-study, and prepared the manuscript	designed and conducted this sub-study, and prepared the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5237283	28086929	AK	2	kindly reviewed and edited this manuscript	kindly reviewed and edited this manuscript	Wrote the paper	Writing - Review & Editing	YES
5237283	28086929	AUS	2	did the statistical analyses presented here and edited the manuscript	did the statistical analyses presented here and edited the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5237283	28086929	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5237283	28086929	BC	2	who supervised this study and contributed equally to the writing of the manuscript	who supervised this study and contributed equally to the writing of the manuscript	Wrote the paper	Supervision|Writing - Original Draft	YES
5237283	28086929	BM	2	performed the resistance testing shown here and contributed to the writing of the manuscript	performed the resistance testing shown here and contributed to the writing of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5237283	28086929	CS	2	assisted greatly in conducting the study, and contributed substantially to the writing of the manuscript	assisted greatly in conducting the study, and contributed substantially to the writing of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5237283	28086929	JF	2	who supervised this study and contributed equally to the writing of the manuscript	who supervised this study and contributed equally to the writing of the manuscript	Wrote the paper	Supervision|Writing - Original Draft	YES
5017982	27613276	AT	2	substantially contributed to the analysis and writing of the manuscript	substantially contributed to the analysis and writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5017982	27613276	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5017982	27613276	KJ	2	developed study procedures, conducted the search, reviewed papers, and wrote the initial drafts of the manuscript	developed study procedures, conducted the search, reviewed papers, and wrote the initial drafts of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5017982	27613276	SM	2	conceived of the study, oversaw all aspects, and wrote drafts of the manuscript	conceived of the study, oversaw all aspects, and wrote drafts of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Supervision|Writing - Original Draft	YES
5237145	28086790	AP	2	contribute to analyze sample collection, perform experiments, qpcr and bioinformatic analyses	contribute to analyze sample collection, perform experiments, qpcr and bioinformatic analyses	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5237145	28086790	BK	2	analyzed qpcr assay	analyzed qpcr assay	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5237145	28086790	BWK	2	designed the experiments, performed the experiments, analyzed the data, bioinformatic analyses and wrote the manuscript	designed the experiments, performed the experiments, analyzed the data, bioinformatic analyses and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5237145	28086790	DC	2	contribute to analyze sample collection, perform experiments, qpcr and bioinformatic analyses	contribute to analyze sample collection, perform experiments, qpcr and bioinformatic analyses	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5237145	28086790	DS	2	analyzed qpcr assay	analyzed qpcr assay	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5237145	28086790	KL	2	contribute to analyze sample collection, perform experiments, qpcr and bioinformatic analyses	contribute to analyze sample collection, perform experiments, qpcr and bioinformatic analyses	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5237145	28086790	NA	2	care the animal handling, sample collection, and data analyses	care the animal handling, sample collection, and data analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5237145	28086790	NH	2	analyzed rna seq data and contribute to edit the manuscript preparation	analyzed rna seq data and contribute to edit the manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5237145	28086790	SD	2	care the animal handling, sample collection, and data analyses	care the animal handling, sample collection, and data analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5237145	28086790	SL	2	analyzed rna seq data	analyzed rna seq data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5237145	28086790	WB	2	designed the experiments, performed the experiments, analyzed the data, bioinformatic analyses and wrote the manuscript	designed the experiments, performed the experiments, analyzed the data, bioinformatic analyses and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5652024	28988979	A.G.	PLoS52	provided rodent biological samples for association analysis	provided rodent biological samples for association analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5652024	28988979	B.S.	PLoS52	provided white adipose samples of obese subjects who received sleeve gastrectomy surgery for weight loss	provided white adipose samples of obese subjects who received sleeve gastrectomy surgery for weight loss	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5652024	28988979	B.Y.	PLoS52	provided subcutaneous adipose samples of subject	provided subcutaneous adipose samples of subject	Contributed reagents/materials/analysis tools	Resources	YES
5652024	28988979	G.N.	PLoS52	conceived the project and designed the experiments|designed and set up the gocy study|are the guarantors of this work and, as such, had full access to all the data in the study and took responsibility for the integrity of the data and the accuracy of the data analysis	conceived the project and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5652024	28988979	G.N.	PLoS52	conceived the project and designed the experiments|designed and set up the gocy study|are the guarantors of this work and, as such, had full access to all the data in the study and took responsibility for the integrity of the data and the accuracy of the data analysis	designed and set up the gocy study	Conceived and designed the experiments|Performed the experiments	Methodology	YES
5652024	28988979	G.N.	PLoS52	conceived the project and designed the experiments|designed and set up the gocy study|are the guarantors of this work and, as such, had full access to all the data in the study and took responsibility for the integrity of the data and the accuracy of the data analysis	are the guarantors of this work and, as such, had full access to all the data in the study and took responsibility for the integrity of the data and the accuracy of the data analysis	Analyzed the data	Data curation|Formal analysis	YES
5652024	28988979	J.H.	PLoS52	designed and set up the gocy study	designed and set up the gocy study	Conceived and designed the experiments|Performed the experiments	Methodology	YES
5652024	28988979	J.J.	PLoS52	provided white adipose samples of obese subjects who received sleeve gastrectomy surgery for weight loss	provided white adipose samples of obese subjects who received sleeve gastrectomy surgery for weight loss	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5652024	28988979	J.S.	PLoS52	recruited obese and control participants in stages one	recruited obese and control participants in stages one	Performed the experiments	Investigation	YES
5652024	28988979	J.W.	PLoS52	conceived the project and designed the experiments|wrote the paper|are the guarantors of this work and, as such, had full access to all the data in the study and took responsibility for the integrity of the data and the accuracy of the data analysis	conceived the project and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5652024	28988979	J.W.	PLoS52	conceived the project and designed the experiments|wrote the paper|are the guarantors of this work and, as such, had full access to all the data in the study and took responsibility for the integrity of the data and the accuracy of the data analysis	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5652024	28988979	J.W.	PLoS52	conceived the project and designed the experiments|wrote the paper|are the guarantors of this work and, as such, had full access to all the data in the study and took responsibility for the integrity of the data and the accuracy of the data analysis	are the guarantors of this work and, as such, had full access to all the data in the study and took responsibility for the integrity of the data and the accuracy of the data analysis	Analyzed the data	Data curation|Formal analysis	YES
5652024	28988979	M.C.	PLoS52	recruited obese and control participants in stages one	recruited obese and control participants in stages one	Performed the experiments	Investigation	YES
5652024	28988979	M.Y.	PLoS52	recruited obese and control participants in stages one	recruited obese and control participants in stages one	Performed the experiments	Investigation	YES
5652024	28988979	N.C.	PLoS52	assisted in some experiments	assisted in some experiments	Performed the experiments	Investigation	YES
5652024	28988979	P.L.	PLoS52	carried out most of the experiments	carried out most of the experiments	Performed the experiments	Investigation	YES
5652024	28988979	Q.C.	PLoS52	provided rodent biological samples for association analysis	provided rodent biological samples for association analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5652024	28988979	Q.M.	PLoS52	provided rodent biological samples for association analysis	provided rodent biological samples for association analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5652024	28988979	R.L.	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5652024	28988979	S.Z.	PLoS52	recruited obese and control participants in stages one	recruited obese and control participants in stages one	Performed the experiments	Investigation	YES
5652024	28988979	T.N.	PLoS52	recruited obese and control participants in stages one|provided rodent biological samples for association analysis	recruited obese and control participants in stages one	Performed the experiments	Investigation	YES
5652024	28988979	T.N.	PLoS52	recruited obese and control participants in stages one|provided rodent biological samples for association analysis	provided rodent biological samples for association analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5652024	28988979	W.G.	PLoS52	conceived the project and designed the experiments|designed and set up the gocy study|are the guarantors of this work and, as such, had full access to all the data in the study and took responsibility for the integrity of the data and the accuracy of the data analysis	conceived the project and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5652024	28988979	W.G.	PLoS52	conceived the project and designed the experiments|designed and set up the gocy study|are the guarantors of this work and, as such, had full access to all the data in the study and took responsibility for the integrity of the data and the accuracy of the data analysis	designed and set up the gocy study	Conceived and designed the experiments|Performed the experiments	Methodology	YES
5652024	28988979	W.G.	PLoS52	conceived the project and designed the experiments|designed and set up the gocy study|are the guarantors of this work and, as such, had full access to all the data in the study and took responsibility for the integrity of the data and the accuracy of the data analysis	are the guarantors of this work and, as such, had full access to all the data in the study and took responsibility for the integrity of the data and the accuracy of the data analysis	Analyzed the data	Data curation|Formal analysis	YES
5652024	28988979	W.L.	PLoS52	recruited obese and control participants in stages one	recruited obese and control participants in stages one	Performed the experiments	Investigation	YES
5652024	28988979	W.W.	PLoS52	conceived the project and designed the experiments|designed and set up the gocy study|are the guarantors of this work and, as such, had full access to all the data in the study and took responsibility for the integrity of the data and the accuracy of the data analysis	conceived the project and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5652024	28988979	W.W.	PLoS52	conceived the project and designed the experiments|designed and set up the gocy study|are the guarantors of this work and, as such, had full access to all the data in the study and took responsibility for the integrity of the data and the accuracy of the data analysis	designed and set up the gocy study	Conceived and designed the experiments|Performed the experiments	Methodology	YES
5652024	28988979	W.W.	PLoS52	conceived the project and designed the experiments|designed and set up the gocy study|are the guarantors of this work and, as such, had full access to all the data in the study and took responsibility for the integrity of the data and the accuracy of the data analysis	are the guarantors of this work and, as such, had full access to all the data in the study and took responsibility for the integrity of the data and the accuracy of the data analysis	Analyzed the data	Data curation|Formal analysis	YES
5652024	28988979	X.D.	PLoS52	provided white adipose samples of obese subjects who received sleeve gastrectomy surgery for weight loss	provided white adipose samples of obese subjects who received sleeve gastrectomy surgery for weight loss	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5652024	28988979	X.Y.	PLoS52	provided white adipose samples of obese subjects who received sleeve gastrectomy surgery for weight loss	provided white adipose samples of obese subjects who received sleeve gastrectomy surgery for weight loss	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5652024	28988979	Y.F.Z.	PLoS52	designed and set up the gocy study	designed and set up the gocy study	Conceived and designed the experiments|Performed the experiments	Methodology	YES
5652024	28988979	Y.S.	PLoS52	recruited obese and control participants in stages one|assisted with statistical analysis	recruited obese and control participants in stages one	Performed the experiments	Investigation	YES
5652024	28988979	Y.S.	PLoS52	recruited obese and control participants in stages one|assisted with statistical analysis	assisted with statistical analysis	Analyzed the data	Formal analysis	YES
5652024	28988979	Y.Z.	PLoS52	carried out most of the experiments|wrote the paper	carried out most of the experiments	Performed the experiments	Investigation	YES
5652024	28988979	Y.Z.	PLoS52	carried out most of the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5419389	28970420	Alla El-Awaisi	2	provided guidance during project completion and revision of the manuscript	provided guidance during project completion and revision of the manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
5419389	28970420	Diana White	2	provided guidance during project completion and revision of the manuscript	provided guidance during project completion and revision of the manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
5419389	28970420	Monica Zolezzi	2	designed, researched and wrote this manuscript	designed, researched and wrote this manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5419389	28970420	Oraib Abdallah	2	designed, researched and wrote this manuscript	designed, researched and wrote this manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5419389	28970420	Stella Major	2	provided guidance during project completion and revision of the manuscript	provided guidance during project completion and revision of the manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
5419389	28970420	Suad Aden	2	designed, researched and wrote this manuscript	designed, researched and wrote this manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4404333	25894322	AJ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4404333	25894322	CE	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4404333	25894322	DO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404333	25894322	DO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4404333	25894322	DO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4404333	25894322	JA	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4404333	25894322	JC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4404333	25894322	JC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404333	25894322	JM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4404333	25894322	JM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404333	25894322	LY	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4404333	25894322	LY	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404333	25894322	MC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4404333	25894322	MC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404333	25894322	RKG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404333	25894322	RKG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404333	25894322	RKG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404333	25894322	SML	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404333	25894322	SML	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404333	25894322	SML	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404333	25894322	WAG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404333	25894322	WAG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4404333	25894322	WAG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4404333	25894322	YS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4404333	25894322	YS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4471256	26146615	John Chang	2	contributed equally to this work	contributed equally to this work	-	-	NO
4471256	26146615	Tomislav Dragovich	2	contributed equally to this work	contributed equally to this work	-	-	NO
4575412	26385853	BOT	2	participated in the design of this review, development of the methodology, writing and in multiple revisions of the manuscript	participated in the design of this review, development of the methodology, writing and in multiple revisions of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Methodology|Writing - Original Draft|Writing - Review & Editing	YES
4575412	26385853	KMM	2	participated in the design, development of the methodology, assessment of contributory articles, writing and in multiple revisions of the manuscript	participated in the design, development of the methodology, assessment of contributory articles, writing and in multiple revisions of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Methodology|Writing - Original Draft|Writing - Review & Editing	YES
4575412	26385853	OAA	2	participated in the design of this review, development of the methodology, retrieval and assessment of contributory articles, writing and in multiple revisions of the manuscript	participated in the design of this review, development of the methodology, retrieval and assessment of contributory articles, writing and in multiple revisions of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Methodology|Writing - Original Draft|Writing - Review & Editing	YES
4575412	26385853	PR	2	participated in the design, retrieval and assessment of contributory articles, and in multiple revisions of the manuscript	participated in the design, retrieval and assessment of contributory articles, and in multiple revisions of the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Review & Editing	YES
4575412	26385853	SJH	2	participated in the design, writing and in multiple revisions of the manuscript	participated in the design, writing and in multiple revisions of the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5515856	28769969	HL	2	contributed to materials	contributed to materials	Contributed reagents/materials/analysis tools	Resources	YES
5515856	28769969	WH	2	initiated and designed the research|performed and analyzed the experiments	initiated and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5515856	28769969	WH	2	initiated and designed the research|performed and analyzed the experiments	performed and analyzed the experiments	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5515856	28769969	YW	2	initiated and designed the research|revised the paper	initiated and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5515856	28769969	YW	2	initiated and designed the research|revised the paper	revised the paper	Wrote the paper	Writing - Review & Editing	YES
5248527	28103895	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5248527	28103895	BP	2	performed data extraction and drafted the manuscript|reviewed and commented on initial and final drafts of the manuscript	performed data extraction and drafted the manuscript	Analyzed the data|Wrote the paper	Data curation|Writing - Original Draft	YES
5248527	28103895	BP	2	performed data extraction and drafted the manuscript|reviewed and commented on initial and final drafts of the manuscript	reviewed and commented on initial and final drafts of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5248527	28103895	DA	2	developed review protocol|reviewed and commented on initial and final drafts of the manuscript	developed review protocol	Conceived and designed the experiments	Methodology	YES
5248527	28103895	DA	2	developed review protocol|reviewed and commented on initial and final drafts of the manuscript	reviewed and commented on initial and final drafts of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5248527	28103895	LR	2	performed literature search|reviewed and commented on initial and final drafts of the manuscript	performed literature search	Performed the experiments	Formal analysis|Investigation	YES
5248527	28103895	LR	2	performed literature search|reviewed and commented on initial and final drafts of the manuscript	reviewed and commented on initial and final drafts of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5248527	28103895	MP	2	developed review protocol|performed literature search|performed data extraction and drafted the manuscript	developed review protocol	Conceived and designed the experiments	Methodology	YES
5248527	28103895	MP	2	developed review protocol|performed literature search|performed data extraction and drafted the manuscript	performed literature search	Performed the experiments	Formal analysis|Investigation	YES
5248527	28103895	MP	2	developed review protocol|performed literature search|performed data extraction and drafted the manuscript	performed data extraction and drafted the manuscript	Analyzed the data|Wrote the paper	Data curation|Writing - Original Draft	YES
5248527	28103895	SC	2	developed review protocol|reviewed and commented on initial and final drafts of the manuscript	developed review protocol	Conceived and designed the experiments	Methodology	YES
5248527	28103895	SC	2	developed review protocol|reviewed and commented on initial and final drafts of the manuscript	reviewed and commented on initial and final drafts of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5248527	28103895	SL	2	developed review protocol|reviewed and commented on initial and final drafts of the manuscript	developed review protocol	Conceived and designed the experiments	Methodology	YES
5248527	28103895	SL	2	developed review protocol|reviewed and commented on initial and final drafts of the manuscript	reviewed and commented on initial and final drafts of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5061679	27734416	All	2	data and materials related to the study can be obtained through contacting the last author at thomas	data and materials related to the study can be obtained through contacting the last author at thomas	-	-	NO
5061679	27734416	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5061679	27734416	EQ	2	supervised the preparation of the manuscript as well as the performance and analyses of the study	supervised the preparation of the manuscript as well as the performance and analyses of the study	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Supervision|Writing - Original Draft	YES
5061679	27734416	MB	2	provided one of the main outcome measures  together with a rater training, and reviewed the manuscript	provided one of the main outcome measures  together with a rater training, and reviewed the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5061679	27734416	Martin Brune	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5061679	27734416	OMalley	2	who proofread the manuscript	who proofread the manuscript	-	-	NO
5061679	27734416	PH	2	took part in the design of the study, recruited subjects, took part in the execution of the study, and reviewed the manuscript	took part in the design of the study, recruited subjects, took part in the execution of the study, and reviewed the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
5061679	27734416	SH	2	took part in the design of the study, prepared the manuscript, recruited subjects and took part in the execution of the study	took part in the design of the study, prepared the manuscript, recruited subjects and took part in the execution of the study	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5061679	27734416	TS	2	took part in the design of the study and supervised the preparation of the manuscript as well as the data collection and analyses of the study	took part in the design of the study and supervised the preparation of the manuscript as well as the data collection and analyses of the study	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Supervision|Writing - Original Draft	YES
4364445	25798217	D.L.	2	contributed equally to this work	contributed equally to this work	-	-	NO
4364445	25798217	D.P.W.	2	contributed equally to this work	contributed equally to this work	-	-	NO
4840395	27144001	Brian O. Kloster	7	Study design, data collection, data analysis, and writing. Jes S. lindholt: Study design, data analysis and writing	Study design, data collection, data analysis, and writing. Jes S. lindholt: Study design, data analysis and writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology	YES
4840395	27144001	Lars Lund	7	Study design, and writing	Study design, and writing	Conceived and designed the experiments|Wrote the paper	Methodology	YES
4404334	25894841	CMC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404334	25894841	CWW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404334	25894841	CWW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404334	25894841	CWW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404334	25894841	FX	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404334	25894841	HKL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404334	25894841	HMT	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404334	25894841	KHL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404334	25894841	SHK	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404334	25894841	SHL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4404334	25894841	WLC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4404334	25894841	WYC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404334	25894841	YCL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5237151	28086803	ABO	2	initiated the project and supervised research	initiated the project and supervised research	Conceived and designed the experiments	Conceptualization|Supervision	YES
5237151	28086803	ABS	2	performed sample preparation for mouse and rat transcriptomic analyses	performed sample preparation for mouse and rat transcriptomic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5237151	28086803	CP	2	generated tools and reagents	generated tools and reagents	Performed the experiments	Investigation	YES
5237151	28086803	CQY	2	generated tools and reagents	generated tools and reagents	Performed the experiments	Investigation	YES
5237151	28086803	IDM	2	performed sample preparation for mouse and rat transcriptomic analyses	performed sample preparation for mouse and rat transcriptomic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5237151	28086803	JDW	2	performed sample preparation for mouse and rat transcriptomic analyses	performed sample preparation for mouse and rat transcriptomic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5237151	28086803	JL	2	carried out and supervised animal experiments|performed statistical and bioinformatics analyses	carried out and supervised animal experiments	Performed the experiments	Investigation|Supervision	YES
5237151	28086803	JL	2	carried out and supervised animal experiments|performed statistical and bioinformatics analyses	performed statistical and bioinformatics analyses	Analyzed the data	Formal analysis	YES
5237151	28086803	KEH	2	performed statistical and bioinformatics analyses	performed statistical and bioinformatics analyses	Analyzed the data	Formal analysis	YES
5237151	28086803	LCC	2	generated tools and reagents	generated tools and reagents	Performed the experiments	Investigation	YES
5237151	28086803	NJH	2	generated tools and reagents	generated tools and reagents	Performed the experiments	Investigation	YES
5237151	28086803	PCB	2	initiated the project and supervised research	initiated the project and supervised research	Conceived and designed the experiments	Conceptualization|Supervision	YES
5237151	28086803	RP	2	carried out and supervised animal experiments|initiated the project and supervised research	carried out and supervised animal experiments	Performed the experiments	Investigation|Supervision	YES
5237151	28086803	RP	2	carried out and supervised animal experiments|initiated the project and supervised research	initiated the project and supervised research	Conceived and designed the experiments	Conceptualization|Supervision	YES
5237151	28086803	RPang	2	generated tools and reagents	generated tools and reagents	Performed the experiments	Investigation	YES
5237151	28086803	RXS	2	performed statistical and bioinformatics analyses	performed statistical and bioinformatics analyses	Analyzed the data	Formal analysis	YES
5237151	28086803	SDP	2	performed sample preparation for mouse and rat transcriptomic analyses|performed statistical and bioinformatics analyses|wrote the first draft of the manuscript	performed sample preparation for mouse and rat transcriptomic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5237151	28086803	SDP	2	performed sample preparation for mouse and rat transcriptomic analyses|performed statistical and bioinformatics analyses|wrote the first draft of the manuscript	performed statistical and bioinformatics analyses	Analyzed the data	Formal analysis	YES
5237151	28086803	SDP	2	performed sample preparation for mouse and rat transcriptomic analyses|performed statistical and bioinformatics analyses|wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
5237151	28086803	SL	2	carried out and supervised animal experiments	carried out and supervised animal experiments	Performed the experiments	Investigation|Supervision	YES
5515866	28769951	CV	2	designed the study and prepared the manuscript	designed the study and prepared the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5515866	28769951	EdlR	2	designed the study, harvested samples, collected the data, analyzed the data, wrote the first draft, and prepared the manuscript	designed the study, harvested samples, collected the data, analyzed the data, wrote the first draft, and prepared the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5515866	28769951	IP-R	2	designed the study and prepared the manuscript	designed the study and prepared the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5515866	28769951	RV	2	designed the study and prepared the manuscript	designed the study and prepared the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5515866	28769951	TM	2	designed the study and prepared the manuscript	designed the study and prepared the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4404335	25894539	IK	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404335	25894539	KS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4404335	25894539	KS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4404335	25894539	KS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404335	25894539	TK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404335	25894539	TK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404335	25894539	TK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404335	25894539	TK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404335	25894539	YO	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404335	25894539	YO	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404335	25894539	YY	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4471259	26146626	Alessandra Zonari	2	contributed to experiment design, data analysis, and paper revision	contributed to experiment design, data analysis, and paper revision	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Review & Editing	YES
4471259	26146626	Alfredo Miranda Goes	2	performed study conception and design, data analysis and interpretation, provision of study materials, and paper writing	performed study conception and design, data analysis and interpretation, provision of study materials, and paper writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology	YES
4471259	26146626	Ana Claudia Chagas	2	contributed to experiment design, allogeneic serum obtention, cell isolation, and culture and differentiation, in addition to paper revision	contributed to experiment design, allogeneic serum obtention, cell isolation, and culture and differentiation, in addition to paper revision	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
4471259	26146626	Dawidson Assis Gomes	2	performed study conception and design, data analysis and interpretation, provision of study materials, and paper writing	performed study conception and design, data analysis and interpretation, provision of study materials, and paper writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology	YES
4471259	26146626	Juliana Lott	2	performed experiment design, cell culture and differentiation, aorta decellularization and seeding, immunostainings, data analysis, and paper writing	performed experiment design, cell culture and differentiation, aorta decellularization and seeding, immunostainings, data analysis, and paper writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology	YES
4471259	26146626	Mata Martins	2	contributed to experiment design, data analysis, figure preparation, and paper revision	contributed to experiment design, data analysis, figure preparation, and paper revision	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Visualization|Writing - Review & Editing	YES
4471259	26146626	Thais Maria	2	contributed to experiment design, data analysis, figure preparation, and paper revision	contributed to experiment design, data analysis, figure preparation, and paper revision	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Visualization|Writing - Review & Editing	YES
5672078	27649638	H.K.	PLoS52	designed the study|performed the research|analyzed the data|wrote the paper|recruited participants and acted as clinicians	designed the study	Conceived and designed the experiments	Methodology	YES
5672078	27649638	H.K.	PLoS52	designed the study|performed the research|analyzed the data|wrote the paper|recruited participants and acted as clinicians	performed the research	Performed the experiments	Investigation	YES
5672078	27649638	H.K.	PLoS52	designed the study|performed the research|analyzed the data|wrote the paper|recruited participants and acted as clinicians	analyzed the data	Analyzed the data	Formal analysis	YES
5672078	27649638	H.K.	PLoS52	designed the study|performed the research|analyzed the data|wrote the paper|recruited participants and acted as clinicians	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5672078	27649638	H.K.	PLoS52	designed the study|performed the research|analyzed the data|wrote the paper|recruited participants and acted as clinicians	recruited participants and acted as clinicians	Performed the experiments	Investigation	YES
5672078	27649638	H.M.	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5672078	27649638	I.N.	PLoS52	performed the research	performed the research	Performed the experiments	Investigation	YES
5672078	27649638	N.O.	PLoS52	recruited participants and acted as clinicians	recruited participants and acted as clinicians	Performed the experiments	Investigation	YES
5672078	27649638	R.K.	PLoS52	contributed new reagents/analytic tools	contributed new reagents/analytic tools	Contributed reagents/materials/analysis tools	Resources	YES
5672078	27649638	S.K.	PLoS52	contributed new reagents/analytic tools	contributed new reagents/analytic tools	Contributed reagents/materials/analysis tools	Resources	YES
5672078	27649638	T.O.	PLoS52	designed the study|performed the research|wrote the paper	designed the study	Conceived and designed the experiments	Methodology	YES
5672078	27649638	T.O.	PLoS52	designed the study|performed the research|wrote the paper	performed the research	Performed the experiments	Investigation	YES
5672078	27649638	T.O.	PLoS52	designed the study|performed the research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5672078	27649638	T.U.	PLoS52	designed the study|performed the research|analyzed the data|wrote the paper	designed the study	Conceived and designed the experiments	Methodology	YES
5672078	27649638	T.U.	PLoS52	designed the study|performed the research|analyzed the data|wrote the paper	performed the research	Performed the experiments	Investigation	YES
5672078	27649638	T.U.	PLoS52	designed the study|performed the research|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5672078	27649638	T.U.	PLoS52	designed the study|performed the research|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5672078	27649638	Y.H.	PLoS52	designed the study|wrote the paper	designed the study	Conceived and designed the experiments	Methodology	YES
5672078	27649638	Y.H.	PLoS52	designed the study|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5061680	27734417	All authors	2	contributed to the design of the study|reviewed and approved the final text of the manuscript|read and approved the final manucsript	contributed to the design of the study	Conceived and designed the experiments	Methodology	YES
5061680	27734417	All authors	2	contributed to the design of the study|reviewed and approved the final text of the manuscript|read and approved the final manucsript	reviewed and approved the final text of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5061680	27734417	All authors	2	contributed to the design of the study|reviewed and approved the final text of the manuscript|read and approved the final manucsript	read and approved the final manucsript	-	-	NO
5061680	27734417	KG	2	wrote the initial draft of the manuscript	wrote the initial draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
5260017	28114955	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5260017	28114955	CZ	2	implemented the study and analyzed results	implemented the study and analyzed results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5260017	28114955	HZ	2	contributed to the acquisition of data and critical revision	contributed to the acquisition of data and critical revision	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Resources|Writing - Review & Editing	YES
5260017	28114955	LM	2	carried out statistical analysis	carried out statistical analysis	Analyzed the data	Formal analysis	YES
5260017	28114955	WW	2	carried out statistical analysis	carried out statistical analysis	Analyzed the data	Formal analysis	YES
5260017	28114955	XL	2	implemented the study and analyzed results|drafted the manuscript|completed the sample collection and the cd4 cell count assay	implemented the study and analyzed results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5260017	28114955	XL	2	implemented the study and analyzed results|drafted the manuscript|completed the sample collection and the cd4 cell count assay	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5260017	28114955	XL	2	implemented the study and analyzed results|drafted the manuscript|completed the sample collection and the cd4 cell count assay	completed the sample collection and the cd4 cell count assay	Performed the experiments	Investigation	YES
5260017	28114955	YL	2	completed the sample collection and the cd4 cell count assay	completed the sample collection and the cd4 cell count assay	Performed the experiments	Investigation	YES
5260017	28114955	YZ	2	contributed to the acquisition of data and critical revision	contributed to the acquisition of data and critical revision	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Resources|Writing - Review & Editing	YES
5237217	28086785	All authors	2	including those not specifically mentioned with tasks as above, contributed to the design of the study, interpretation of the results, and approved the final version of the manuscript	including those not specifically mentioned with tasks as above, contributed to the design of the study, interpretation of the results, and approved the final version of the manuscript	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5237217	28086785	BBS	2	conducted genotyping and data quality checks	conducted genotyping and data quality checks	Performed the experiments	Data curation|Investigation	YES
5237217	28086785	FB	2	contributed to simulations	contributed to simulations	-	Formal analysis	YES
5237217	28086785	GD	2	conducted genotyping and data quality checks	conducted genotyping and data quality checks	Performed the experiments	Data curation|Investigation	YES
5237217	28086785	HJS	2	contributed to simulations	contributed to simulations	-	Formal analysis	YES
5237217	28086785	KAG	2	conceived and managed the study	conceived and managed the study	Conceived and designed the experiments	Conceptualization|Project administration	YES
5237217	28086785	KM	2	conducted all bioinformatics analysis, wrote the first draft of the manuscript, and coordinated mathematical simulations	conducted all bioinformatics analysis, wrote the first draft of the manuscript, and coordinated mathematical simulations	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Project administration|Writing - Original Draft	YES
5237217	28086785	MQ	2	contributed to simulations	contributed to simulations	-	Formal analysis	YES
5237217	28086785	NK	2	organized sequencing	organized sequencing	Performed the experiments	Investigation	YES
5237217	28086785	RSM	2	organized sequencing	organized sequencing	Performed the experiments	Investigation	YES
5419392	28970426	Beverly FitzPatrick	PLoS52	conceived and designed the paper|wrote the paper	conceived and designed the paper	Conceived and designed the experiments	Conceptualization	YES
5419392	28970426	Beverly FitzPatrick	PLoS52	conceived and designed the paper|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5419392	28970426	John Hawboldt	PLoS52	conceived and designed the paper|aligned the stated competencies/outcomes|wrote the paper	conceived and designed the paper	Conceived and designed the experiments	Conceptualization	YES
5419392	28970426	John Hawboldt	PLoS52	conceived and designed the paper|aligned the stated competencies/outcomes|wrote the paper	aligned the stated competencies/outcomes	Analyzed the data	Formal analysis	YES
5419392	28970426	John Hawboldt	PLoS52	conceived and designed the paper|aligned the stated competencies/outcomes|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5419392	28970426	Rose Nash	PLoS52	conceived and designed the paper|aligned the stated competencies/outcomes|wrote the paper	conceived and designed the paper	Conceived and designed the experiments	Conceptualization	YES
5419392	28970426	Rose Nash	PLoS52	conceived and designed the paper|aligned the stated competencies/outcomes|wrote the paper	aligned the stated competencies/outcomes	Analyzed the data	Formal analysis	YES
5419392	28970426	Rose Nash	PLoS52	conceived and designed the paper|aligned the stated competencies/outcomes|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404336	25894584	BS	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404336	25894584	BS	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404336	25894584	MW	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404336	25894584	MW	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404336	25894584	NHL	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404336	25894584	NHL	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404336	25894584	RHM	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404336	25894584	RHM	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5515871	28769963	CR-D	PLoS52	assisted in the data analysis	assisted in the data analysis	Analyzed the data	Formal analysis	YES
5515871	28769963	DW	PLoS52	participated in the design of the study, analyzed the data, and wrote the paper	participated in the design of the study, analyzed the data, and wrote the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5515871	28769963	EP	PLoS52	secured funding, conceived and designed the study, coordinated the experiments and data analysis, and co-wrote the paper	secured funding, conceived and designed the study, coordinated the experiments and data analysis, and co-wrote the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Funding acquisition|Methodology|Project administration|Writing - Original Draft	YES
5515871	28769963	RA	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5515871	28769963	RE	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5515871	28769963	RP	PLoS52	secured funding, conceived and designed the study, coordinated the experiments and data analysis, and co-wrote the paper	secured funding, conceived and designed the study, coordinated the experiments and data analysis, and co-wrote the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Funding acquisition|Methodology|Project administration|Writing - Original Draft	YES
4581083	26198351	AL	2	contributed to the initial outline and subsequent drafts, added specific content and assisted in editing the final draft of the paper	contributed to the initial outline and subsequent drafts, added specific content and assisted in editing the final draft of the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4581083	26198351	All authors	2	have read and approved the final version of the paper|have read and approved the final version|contributed to revisions and approved the final version of the report|contributed to the overall content plan|have read and approved the final version and contributed equally to the conclusions|have read and approved the final version|have read and approved the final version|contributed to the writing of the manuscript, and all approved the final draft	have read and approved the final version of the paper	-	-	NO
4581083	26198351	All authors	2	have read and approved the final version of the paper|have read and approved the final version|contributed to revisions and approved the final version of the report|contributed to the overall content plan|have read and approved the final version and contributed equally to the conclusions|have read and approved the final version|have read and approved the final version|contributed to the writing of the manuscript, and all approved the final draft	have read and approved the final version	-	-	NO
4581083	26198351	All authors	2	have read and approved the final version of the paper|have read and approved the final version|contributed to revisions and approved the final version of the report|contributed to the overall content plan|have read and approved the final version and contributed equally to the conclusions|have read and approved the final version|have read and approved the final version|contributed to the writing of the manuscript, and all approved the final draft	contributed to revisions and approved the final version of the report	Wrote the paper	Writing - Review & Editing	YES
4581083	26198351	All authors	2	have read and approved the final version of the paper|have read and approved the final version|contributed to revisions and approved the final version of the report|contributed to the overall content plan|have read and approved the final version and contributed equally to the conclusions|have read and approved the final version|have read and approved the final version|contributed to the writing of the manuscript, and all approved the final draft	contributed to the overall content plan	-	-	NO
4581083	26198351	All authors	2	have read and approved the final version of the paper|have read and approved the final version|contributed to revisions and approved the final version of the report|contributed to the overall content plan|have read and approved the final version and contributed equally to the conclusions|have read and approved the final version|have read and approved the final version|contributed to the writing of the manuscript, and all approved the final draft	have read and approved the final version and contributed equally to the conclusions	-	-	NO
4581083	26198351	All authors	2	have read and approved the final version of the paper|have read and approved the final version|contributed to revisions and approved the final version of the report|contributed to the overall content plan|have read and approved the final version and contributed equally to the conclusions|have read and approved the final version|have read and approved the final version|contributed to the writing of the manuscript, and all approved the final draft	have read and approved the final version	-	-	NO
4581083	26198351	All authors	2	have read and approved the final version of the paper|have read and approved the final version|contributed to revisions and approved the final version of the report|contributed to the overall content plan|have read and approved the final version and contributed equally to the conclusions|have read and approved the final version|have read and approved the final version|contributed to the writing of the manuscript, and all approved the final draft	have read and approved the final version	-	-	NO
4581083	26198351	All authors	2	have read and approved the final version of the paper|have read and approved the final version|contributed to revisions and approved the final version of the report|contributed to the overall content plan|have read and approved the final version and contributed equally to the conclusions|have read and approved the final version|have read and approved the final version|contributed to the writing of the manuscript, and all approved the final draft	contributed to the writing of the manuscript, and all approved the final draft	Wrote the paper	Writing - Original Draft	YES
4581083	26198351	BLJ	2	conducted the analyses, and all authors contributed to the writing of the manuscript	conducted the analyses, and all authors contributed to the writing of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4581083	26198351	Both authors	2	have read and approved the final version	have read and approved the final version	-	-	NO
4581083	26198351	CC	2	conceived and designed the study|wrote the first draft of the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4581083	26198351	CC	2	conceived and designed the study|wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
4581083	26198351	CH	2	suggested a framework for the manuscript|wrote sections of the manuscript|compiled the final draft	suggested a framework for the manuscript	-	-	NO
4581083	26198351	CH	2	suggested a framework for the manuscript|wrote sections of the manuscript|compiled the final draft	wrote sections of the manuscript	Wrote the paper	Writing - Original Draft	YES
4581083	26198351	CH	2	suggested a framework for the manuscript|wrote sections of the manuscript|compiled the final draft	compiled the final draft	Wrote the paper	Writing - Original Draft	YES
4581083	26198351	Carlos F. Caceres	2	wrote the first manuscript draft, coordinated and incorporated input from co-authors, and completed the manuscript	wrote the first manuscript draft, coordinated and incorporated input from co-authors, and completed the manuscript	Wrote the paper	Project administration|Writing - Original Draft	YES
4581083	26198351	DC	2	researched and wrote the introduction, and coordinated the final draft of the manuscript	researched and wrote the introduction, and coordinated the final draft of the manuscript	Wrote the paper	Project administration|Writing - Original Draft	YES
4581083	26198351	DK	2	contributed to the initial outline and subsequent drafts, added specific content and assisted in editing the final draft of the paper	contributed to the initial outline and subsequent drafts, added specific content and assisted in editing the final draft of the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4581083	26198351	FM	2	conceived and designed the analysis	conceived and designed the analysis	Conceived and designed the experiments	Conceptualization	YES
4581083	26198351	FV	2	did the first draft together, and all co-authors have contributed to subsequent drafts and revisions and have signed off on the final manuscript	did the first draft together, and all co-authors have contributed to subsequent drafts and revisions and have signed off on the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4581083	26198351	FvG	2	researched and wrote the introduction, and coordinated the final draft of the manuscript	researched and wrote the introduction, and coordinated the final draft of the manuscript	Wrote the paper	Project administration|Writing - Original Draft	YES
4581083	26198351	IC	2	conceived and designed the analysis|conducted the analyses, and all authors contributed to the writing of the manuscript	conceived and designed the analysis	Conceived and designed the experiments	Conceptualization	YES
4581083	26198351	IC	2	conceived and designed the analysis|conducted the analyses, and all authors contributed to the writing of the manuscript	conducted the analyses, and all authors contributed to the writing of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4581083	26198351	JMB	2	conceived and designed the study|wrote the first draft of the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4581083	26198351	JMB	2	conceived and designed the study|wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
4581083	26198351	JP	2	contributed to the initial outline and subsequent drafts, added specific content and assisted in editing the final draft of the paper	contributed to the initial outline and subsequent drafts, added specific content and assisted in editing the final draft of the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4581083	26198351	Judith Auerbach	2	led the writing process and wrote the first draft of the paper	led the writing process and wrote the first draft of the paper	Wrote the paper	Writing - Original Draft	YES
4581083	26198351	KHM	2	conceptualized and wrote the first draft of the manuscript and addressed reviewer comments	conceptualized and wrote the first draft of the manuscript and addressed reviewer comments	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
4581083	26198351	KO	2	conceived and designed the analysis	conceived and designed the analysis	Conceived and designed the experiments	Conceptualization	YES
4581083	26198351	LGB	2	did the first draft together, and all co-authors have contributed to subsequent drafts and revisions and have signed off on the final manuscript	did the first draft together, and all co-authors have contributed to subsequent drafts and revisions and have signed off on the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4581083	26198351	MS	2	wrote the first draft of the report	wrote the first draft of the report	Wrote the paper	Writing - Original Draft	YES
4581083	26198351	MW	2	contributed to the initial outline and subsequent drafts, added specific content and assisted in editing the final draft of the paper|wrote sections of the manuscript	contributed to the initial outline and subsequent drafts, added specific content and assisted in editing the final draft of the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4581083	26198351	MW	2	contributed to the initial outline and subsequent drafts, added specific content and assisted in editing the final draft of the paper|wrote sections of the manuscript	wrote sections of the manuscript	Wrote the paper	Writing - Original Draft	YES
4581083	26198351	OReilly	2	provided substantial comments to the earlier drafts	provided substantial comments to the earlier drafts	Wrote the paper	Writing - Original Draft	YES
4581083	26198351	Peter Godfrey-Fausset	2	provided key ideas for some of the main arguments presented in the paper	provided key ideas for some of the main arguments presented in the paper	Conceived and designed the experiments	Conceptualization	YES
4581083	26198351	RG	2	contributed to the initial outline and subsequent drafts, added specific content and assisted in editing the final draft of the paper	contributed to the initial outline and subsequent drafts, added specific content and assisted in editing the final draft of the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4581083	26198351	RH	2	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4581083	26198351	RM	2	wrote sections of the manuscript	wrote sections of the manuscript	Wrote the paper	Writing - Original Draft	YES
4581083	26198351	RVB	2	conceived and designed the study|wrote the first draft of the report	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4581083	26198351	RVB	2	conceived and designed the study|wrote the first draft of the report	wrote the first draft of the report	Wrote the paper	Writing - Original Draft	YES
4581083	26198351	RY	2	collected the cost data	collected the cost data	Performed the experiments	Investigation	YES
4581083	26198351	SC	2	contributed to the initial outline and subsequent drafts, added specific content and assisted in editing the final draft of the paper	contributed to the initial outline and subsequent drafts, added specific content and assisted in editing the final draft of the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4581083	26198351	SH	2	contributed to the initial outline and subsequent drafts, added specific content and assisted in editing the final draft of the paper	contributed to the initial outline and subsequent drafts, added specific content and assisted in editing the final draft of the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4581083	26198351	Salif Sow	2	provided substantial comments to the earlier drafts	provided substantial comments to the earlier drafts	Wrote the paper	Writing - Original Draft	YES
4581083	26198351	TBH	2	conceived and designed the analysis	conceived and designed the analysis	Conceived and designed the experiments	Conceptualization	YES
4581083	26198351	The authors	2	jointly conceived and wrote this commentary	jointly conceived and wrote this commentary	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4581083	26198351	Trevor Hoppe	2	contributed significantly to the concepts and ideas in the text and to its further iterations	contributed significantly to the concepts and ideas in the text and to its further iterations	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5672080	28655596	All authors	PLoS52	interpreted the data and revised the manuscript for important intellectual content and approved the final draft	interpreted the data and revised the manuscript for important intellectual content and approved the final draft	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5672080	28655596	D.J.	PLoS52	enrolled the participants	enrolled the participants	Performed the experiments	Investigation	YES
5672080	28655596	D.L.	PLoS52	obtained the study funding|conceived and designed the study|provided administrative support|revised the manuscript	obtained the study funding	-	Funding acquisition	YES
5672080	28655596	D.L.	PLoS52	obtained the study funding|conceived and designed the study|provided administrative support|revised the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5672080	28655596	D.L.	PLoS52	obtained the study funding|conceived and designed the study|provided administrative support|revised the manuscript	provided administrative support	-	Project administration	YES
5672080	28655596	D.L.	PLoS52	obtained the study funding|conceived and designed the study|provided administrative support|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5672080	28655596	F.W.	PLoS52	conceived and designed the study|developed the protocol and conducted the study with all other authors|analyzed the data|wrote the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5672080	28655596	F.W.	PLoS52	conceived and designed the study|developed the protocol and conducted the study with all other authors|analyzed the data|wrote the manuscript	developed the protocol and conducted the study with all other authors	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5672080	28655596	F.W.	PLoS52	conceived and designed the study|developed the protocol and conducted the study with all other authors|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5672080	28655596	F.W.	PLoS52	conceived and designed the study|developed the protocol and conducted the study with all other authors|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5672080	28655596	J.G.	PLoS52	enrolled the participants	enrolled the participants	Performed the experiments	Investigation	YES
5672080	28655596	J.L.	PLoS52	enrolled the participants	enrolled the participants	Performed the experiments	Investigation	YES
5672080	28655596	J.M.	PLoS52	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5672080	28655596	J.Y.	PLoS52	provided administrative support	provided administrative support	-	Project administration	YES
5672080	28655596	J.Z.	PLoS52	enrolled the participants|analyzed the data	enrolled the participants	Performed the experiments	Investigation	YES
5672080	28655596	J.Z.	PLoS52	enrolled the participants|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5672080	28655596	T.H.	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5672080	28655596	Y.W.	PLoS52	conceived and designed the study|developed the protocol and conducted the study with all other authors|analyzed the data|wrote the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5672080	28655596	Y.W.	PLoS52	conceived and designed the study|developed the protocol and conducted the study with all other authors|analyzed the data|wrote the manuscript	developed the protocol and conducted the study with all other authors	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5672080	28655596	Y.W.	PLoS52	conceived and designed the study|developed the protocol and conducted the study with all other authors|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5672080	28655596	Y.W.	PLoS52	conceived and designed the study|developed the protocol and conducted the study with all other authors|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5672080	28655596	Z.J.	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
4840397	27144003	Ignacio Rivera-Chavarria	7	writing the paper, final approval	writing the paper, final approval	Wrote the paper	Writing - Original Draft	YES
4840397	27144003	Jose D. Brenes-Gutierrez	7	writing the paper, final approval	writing the paper, final approval	Wrote the paper	Writing - Original Draft	YES
5069208	27757849	All authors	2	collaborated in the recruitment of patients|read and approved the final manuscript	collaborated in the recruitment of patients	Performed the experiments	Investigation	YES
5069208	27757849	All authors	2	collaborated in the recruitment of patients|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5069208	27757849	GP	2	developed the hypothesis and design of the study and managed literature searches|reviewed the final draft thoroughly and was responsible for the last version	developed the hypothesis and design of the study and managed literature searches	Conceived and designed the experiments	Conceptualization|Formal analysis|Methodology	YES
5069208	27757849	GP	2	developed the hypothesis and design of the study and managed literature searches|reviewed the final draft thoroughly and was responsible for the last version	reviewed the final draft thoroughly and was responsible for the last version	Wrote the paper	Writing - Original Draft	YES
5069208	27757849	SA	2	undertook statistical analysis and wrote the draft manuscript, and all authors supervised and made contributions to it	undertook statistical analysis and wrote the draft manuscript, and all authors supervised and made contributions to it	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Supervision|Writing - Original Draft	YES
5419393	28970424	Ieva Stupans	PLoS52	administered the surveys|carried out thematic analysis of social media comments	administered the surveys	Performed the experiments	Investigation	YES
5419393	28970424	Ieva Stupans	PLoS52	administered the surveys|carried out thematic analysis of social media comments	carried out thematic analysis of social media comments	Performed the experiments	Investigation	YES
5419393	28970424	Jose Manuel Serrano	PLoS52	carried out thematic analysis of social media comments	carried out thematic analysis of social media comments	Performed the experiments	Investigation	YES
5419393	28970424	Leanne Chalmers	PLoS52	administered the surveys|wrote the paper	administered the surveys	Performed the experiments	Investigation	YES
5419393	28970424	Leanne Chalmers	PLoS52	administered the surveys|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5419393	28970424	Lisa M. Nissen	PLoS52	administered the surveys|wrote the paper	administered the surveys	Performed the experiments	Investigation	YES
5419393	28970424	Lisa M. Nissen	PLoS52	administered the surveys|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5419393	28970424	Natalie Brown	PLoS52	administered the surveys|carried out thematic analysis of social media comments|wrote the paper	administered the surveys	Performed the experiments	Investigation	YES
5419393	28970424	Natalie Brown	PLoS52	administered the surveys|carried out thematic analysis of social media comments|wrote the paper	carried out thematic analysis of social media comments	Performed the experiments	Investigation	YES
5419393	28970424	Natalie Brown	PLoS52	administered the surveys|carried out thematic analysis of social media comments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5419393	28970424	Rose Nash	PLoS52	conceived and designed the paper|administered the surveys|analysed the survey data	conceived and designed the paper	Conceived and designed the experiments	Conceptualization	YES
5419393	28970424	Rose Nash	PLoS52	conceived and designed the paper|administered the surveys|analysed the survey data	administered the surveys	Performed the experiments	Investigation	YES
5419393	28970424	Rose Nash	PLoS52	conceived and designed the paper|administered the surveys|analysed the survey data	analysed the survey data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5419393	28970424	T. L. Lau	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5419393	28970424	Wendy Thompson	PLoS52	conceived and designed the paper|administered the surveys|analysed the survey data	conceived and designed the paper	Conceived and designed the experiments	Conceptualization	YES
5419393	28970424	Wendy Thompson	PLoS52	conceived and designed the paper|administered the surveys|analysed the survey data	administered the surveys	Performed the experiments	Investigation	YES
5419393	28970424	Wendy Thompson	PLoS52	conceived and designed the paper|administered the surveys|analysed the survey data	analysed the survey data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4840398	27144008	HO	2	discussed and advised about the treatment for this patient	discussed and advised about the treatment for this patient	Performed the experiments	Investigation	YES
4840398	27144008	KA	2	discussed and advised about the treatment for this patient	discussed and advised about the treatment for this patient	Performed the experiments	Investigation	YES
4840398	27144008	KK	2	discussed and advised about the treatment for this patient	discussed and advised about the treatment for this patient	Performed the experiments	Investigation	YES
4840398	27144008	KN	2	mainly performed medical examinations and surgery for this patient	mainly performed medical examinations and surgery for this patient	Performed the experiments	Investigation	YES
4840398	27144008	MK	2	discussed and advised about the treatment for this patient	discussed and advised about the treatment for this patient	Performed the experiments	Investigation	YES
4840398	27144008	OO	2	discussed and advised about the treatment for this patient	discussed and advised about the treatment for this patient	Performed the experiments	Investigation	YES
4840398	27144008	YS	2	mainly make this manuscript and was an assistant of operative procedure	mainly make this manuscript and was an assistant of operative procedure	Performed the experiments	Investigation	YES
5237228	28086860	DL	2	performed the mass spectrometry analysis, inferred tissue-preferentiality of expression for metabolites and developed the gene-to-metabolite co-expression and metabolite similarity analysis	performed the mass spectrometry analysis, inferred tissue-preferentiality of expression for metabolites and developed the gene-to-metabolite co-expression and metabolite similarity analysis	Performed the experiments	Investigation	YES
5237228	28086860	EG	2	performed the mass spectrometry analysis, inferred tissue-preferentiality of expression for metabolites and developed the gene-to-metabolite co-expression and metabolite similarity analysis	performed the mass spectrometry analysis, inferred tissue-preferentiality of expression for metabolites and developed the gene-to-metabolite co-expression and metabolite similarity analysis	Performed the experiments	Investigation	YES
5237228	28086860	SX	2	designed and developed the database system|generated gene annotations and analyzed data|wrote the manuscript	designed and developed the database system	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Methodology|Software	YES
5237228	28086860	SX	2	designed and developed the database system|generated gene annotations and analyzed data|wrote the manuscript	generated gene annotations and analyzed data	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5237228	28086860	SX	2	designed and developed the database system|generated gene annotations and analyzed data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5237228	28086860	TB	2	designed and developed the database system|generated gene annotations and analyzed data|wrote the manuscript	designed and developed the database system	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Methodology|Software	YES
5237228	28086860	TB	2	designed and developed the database system|generated gene annotations and analyzed data|wrote the manuscript	generated gene annotations and analyzed data	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5237228	28086860	TB	2	designed and developed the database system|generated gene annotations and analyzed data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5237228	28086860	ZL	2	generated gene annotations and analyzed data	generated gene annotations and analyzed data	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
4471304	26146616	Di Zhu	2	contributed equally to this work	contributed equally to this work	-	-	NO
4471304	26146616	Liping Wei	2	contributed equally to this work	contributed equally to this work	-	-	NO
4471304	26146616	Xiaotian Zhang	2	contributed equally to this work	contributed equally to this work	-	-	NO
4404337	25894969	CS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4404337	25894969	KS	PLoS5	Wrote the paper|Contributed clinical patient data	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404337	25894969	KS	PLoS5	Wrote the paper|Contributed clinical patient data	Contributed clinical patient data	Contributed reagents/materials/analysis tools	Resources	YES
4404337	25894969	KZ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404337	25894969	LK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4404337	25894969	MMJK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Contributed clinical patient data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404337	25894969	MMJK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Contributed clinical patient data	Performed the experiments	Performed the experiments	Investigation	YES
4404337	25894969	MMJK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Contributed clinical patient data	Analyzed the data	Analyzed the data	Formal analysis	YES
4404337	25894969	MMJK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Contributed clinical patient data	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404337	25894969	MMJK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Contributed clinical patient data	Contributed clinical patient data	Contributed reagents/materials/analysis tools	Resources	YES
4404337	25894969	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404337	25894969	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404337	25894969	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404337	25894969	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404337	25894969	MZ	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404337	25894969	MZ	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404337	25894969	NC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4404337	25894969	NO	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404337	25894969	NO	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404337	25894969	SI	PLoS5	Contributed clinical patient data	Contributed clinical patient data	Contributed reagents/materials/analysis tools	Resources	YES
4404337	25894969	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed clinical patient data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404337	25894969	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed clinical patient data	Performed the experiments	Performed the experiments	Investigation	YES
4404337	25894969	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed clinical patient data	Analyzed the data	Analyzed the data	Formal analysis	YES
4404337	25894969	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed clinical patient data	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404337	25894969	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed clinical patient data	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404337	25894969	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed clinical patient data	Contributed clinical patient data	Contributed reagents/materials/analysis tools	Resources	YES
4404337	25894969	SS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4404337	25894969	THB	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper|Contributed clinical patient data	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404337	25894969	THB	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper|Contributed clinical patient data	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404337	25894969	THB	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper|Contributed clinical patient data	Contributed clinical patient data	Contributed reagents/materials/analysis tools	Resources	YES
5286788	28143541	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5515872	28769973	CZ	PLoS52	analyzed the rna seq data	analyzed the rna seq data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5515872	28769973	DJ	PLoS52	conceived and designed the experiments|wrote the article with	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5515872	28769973	DJ	PLoS52	conceived and designed the experiments|wrote the article with	wrote the article with	Wrote the paper	Writing - Original Draft	YES
5515872	28769973	J-KZ	PLoS52	analyzed the rna seq data	analyzed the rna seq data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5515872	28769973	JC	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5515872	28769973	LW	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5515872	28769973	LZ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5515872	28769973	MH	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5515872	28769973	QZ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5515872	28769973	TD	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5515872	28769973	TS	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the rna seq data|wrote the article with	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5515872	28769973	TS	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the rna seq data|wrote the article with	performed the experiments	Performed the experiments	Investigation	YES
5515872	28769973	TS	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the rna seq data|wrote the article with	analyzed the rna seq data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5515872	28769973	TS	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the rna seq data|wrote the article with	wrote the article with	Wrote the paper	Writing - Original Draft	YES
5515872	28769973	XW	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5515872	28769973	all the authors	PLoS52	contributed with the wrote the article with	contributed with the wrote the article with	Wrote the paper	Writing - Original Draft	YES
4840399	27144004	All authors	2	revised the manuscript critically and gave their final approval	revised the manuscript critically and gave their final approval	Wrote the paper	Writing - Review & Editing	YES
4471310	26146638	Annarita Favia	PLoS52	performed research|analyzed data|wrote the paper	performed research	Performed the experiments	Investigation	YES
4471310	26146638	Annarita Favia	PLoS52	performed research|analyzed data|wrote the paper	analyzed data	Analyzed the data	Formal analysis	YES
4471310	26146638	Annarita Favia	PLoS52	performed research|analyzed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4471310	26146638	Antonio Filippini	PLoS52	designed research|analyzed data|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
4471310	26146638	Antonio Filippini	PLoS52	designed research|analyzed data|wrote the paper	analyzed data	Analyzed the data	Formal analysis	YES
4471310	26146638	Antonio Filippini	PLoS52	designed research|analyzed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4471310	26146638	Elio Ziparo	PLoS52	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
4471310	26146638	Fioretta Palombi	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4471310	26146638	Francesca Papacci	PLoS52	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
4471310	26146638	Guido Gambara	PLoS52	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
4471310	26146638	Irene Pafumi	PLoS52	designed research|performed research|analyzed data|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
4471310	26146638	Irene Pafumi	PLoS52	designed research|performed research|analyzed data|wrote the paper	performed research	Performed the experiments	Investigation	YES
4471310	26146638	Irene Pafumi	PLoS52	designed research|performed research|analyzed data|wrote the paper	analyzed data	Analyzed the data	Formal analysis	YES
4471310	26146638	Irene Pafumi	PLoS52	designed research|performed research|analyzed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5292145	28160772	All	2	participant signed informed consent prior to participation in the study	participant signed informed consent prior to participation in the study	-	-	NO
5292145	28160772	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5292145	28160772	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5237265	28086788	CC	2	critically revised the manuscript, and all authors have read and given approval of the manuscript	critically revised the manuscript, and all authors have read and given approval of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5237265	28086788	CX	2	participated in its design and interpretation	participated in its design and interpretation	Conceived and designed the experiments|Analyzed the data	Formal analysis	YES
5237265	28086788	JG	2	critically revised the manuscript, and all authors have read and given approval of the manuscript	critically revised the manuscript, and all authors have read and given approval of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5237265	28086788	LL	2	wrote the manuscript and analyzed data|conducted the experiments	wrote the manuscript and analyzed data	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5237265	28086788	LL	2	wrote the manuscript and analyzed data|conducted the experiments	conducted the experiments	Performed the experiments	Investigation	YES
5237265	28086788	YC	2	conducted the experiments	conducted the experiments	Performed the experiments	Investigation	YES
5106426	27837521	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5106426	27837521	RWTH	2	aachen university and a travel stipend donated by the glaxosmithkline foundation	aachen university and a travel stipend donated by the glaxosmithkline foundation	Contributed reagents/materials/analysis tools	Resources	YES
5106426	27837521	all other authors	2	the corresponding author states that there are no competing interests	the corresponding author states that there are no competing interests	Analyzed the data	Formal analysis	YES
5515875	28785272	Both authors	2	contributed to the final methodology design, and to the writing of this article	contributed to the final methodology design, and to the writing of this article	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5515875	28785272	MO	2	provided the initial research design and obtained funding	provided the initial research design and obtained funding	Conceived and designed the experiments	Funding acquisition	YES
5515875	28785272	SN	2	developed methodology and computational tools and performed all experiments and analyses	developed methodology and computational tools and performed all experiments and analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5419394	28970422	Andries Koster	2	conceived the paper and wrote the first version	conceived the paper and wrote the first version	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5419394	28970422	Irma Meijerman	2	commented on several draft versions of the paper	commented on several draft versions of the paper	Wrote the paper	Writing - Original Draft	YES
5419394	28970422	Tom Schalekamp	2	commented on several draft versions of the paper	commented on several draft versions of the paper	Wrote the paper	Writing - Original Draft	YES
4843094	27158488	Stephanie Jenkins	4	Jaison Patel - paper written by	Jaison Patel - paper written by	Wrote the paper	Writing - Original Draft	YES
4404338	25894553	BBG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Designed the experiments and made the measurements	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404338	25894553	BBG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Designed the experiments and made the measurements	Performed the experiments	Performed the experiments	Investigation	YES
4404338	25894553	BBG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Designed the experiments and made the measurements	Analyzed the data	Analyzed the data	Formal analysis	YES
4404338	25894553	BBG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Designed the experiments and made the measurements	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404338	25894553	BBG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Designed the experiments and made the measurements	Designed the experiments and made the measurements	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4404338	25894553	HS	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404338	25894553	HS	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404338	25894553	JRP	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Invented the idea on which the paper is based|Designed the experiments and made the measurements	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404338	25894553	JRP	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Invented the idea on which the paper is based|Designed the experiments and made the measurements	Performed the experiments	Performed the experiments	Investigation	YES
4404338	25894553	JRP	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Invented the idea on which the paper is based|Designed the experiments and made the measurements	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404338	25894553	JRP	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Invented the idea on which the paper is based|Designed the experiments and made the measurements	Invented the idea on which the paper is based	Conceived and designed the experiments	Conceptualization	YES
4404338	25894553	JRP	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Invented the idea on which the paper is based|Designed the experiments and made the measurements	Designed the experiments and made the measurements	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5307755	28193244	AW	2	assisted in the design of the project and participated in drafting the manuscript	assisted in the design of the project and participated in drafting the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5307755	28193244	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5307755	28193244	CES	2	conducted lab work, assisted in the data analysis, and drafting some sections of the manuscript	conducted lab work, assisted in the data analysis, and drafting some sections of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5307755	28193244	HCH	2	planned and conducted the lab work	planned and conducted the lab work	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5307755	28193244	KMR	2	identify available specimens and conducted immunological assays	identify available specimens and conducted immunological assays	Performed the experiments	Investigation	YES
5307755	28193244	LMF	2	conceived of the project, analyzed the data, and wrote the manuscript	conceived of the project, analyzed the data, and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
5307755	28193244	Petronella Muresan	2	for identifying appropriate specimens	for identifying appropriate specimens	Performed the experiments	Investigation	YES
5307755	28193244	SN	2	assisted in the design of the project and participated in drafting the manuscript	assisted in the design of the project and participated in drafting the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5307755	28193244	TAW	2	conceived of the project, analyzed the data, and wrote the manuscript	conceived of the project, analyzed the data, and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
5307755	28193244	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
4843096	27158490	Hideo Ichimura	2	participated in the operation or management of the patient in this case|supervised yuichiro ozawa under the	participated in the operation or management of the patient in this case	Performed the experiments	Investigation	YES
4843096	27158490	Hideo Ichimura	2	participated in the operation or management of the patient in this case|supervised yuichiro ozawa under the	supervised yuichiro ozawa under the	-	Supervision	YES
4843096	27158490	Mitsuaki Sakai	2	supervised yuichiro ozawa under the	supervised yuichiro ozawa under the	-	Supervision	YES
4843096	27158490	Yuichiro Ozawa	2	participated in the operation or management of the patient in this case|under the	participated in the operation or management of the patient in this case	Performed the experiments	Investigation	YES
4843096	27158490	Yuichiro Ozawa	2	participated in the operation or management of the patient in this case|under the	under the	-	-	NO
5597085	28975900	All authors	5	contributed to this manuscript through: conception and design of the work	contributed to this manuscript through: conception and design of the work	Conceived and designed the experiments	Conceptualization	YES
5114216	27858348	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5114216	27858348	All three authors	2	were involved in the writing, editing, and reviewing of this manuscript	were involved in the writing, editing, and reviewing of this manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5515879	28769968	HS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5515879	28769968	HS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5515879	28769968	HZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5515879	28769968	WY	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5515879	28769968	WY	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5515879	28769968	WY	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5515879	28769968	WY	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5515879	28769968	XG	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
5515879	28769968	XG	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5515879	28769968	XG	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5515879	28769968	XL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
5515879	28769968	XL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5515879	28769968	XL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4471383	26146639	Alessandra Bitto	2	equally contributed to this work	equally contributed to this work	-	-	NO
4471383	26146639	Natasha Irrera	2	equally contributed to this work	equally contributed to this work	-	-	NO
5704063	29113774	HK	2	assisted with the wrote the manuscript with|designed the study	assisted with the wrote the manuscript with	Wrote the paper	Writing - Original Draft	YES
5704063	29113774	HK	2	assisted with the wrote the manuscript with|designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5704063	29113774	KN	2	supervised the project	supervised the project	-	Supervision	YES
5704063	29113774	MI	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5704063	29113774	MT	2	assisted with the wrote the manuscript with|designed the study	assisted with the wrote the manuscript with	Wrote the paper	Writing - Original Draft	YES
5704063	29113774	MT	2	assisted with the wrote the manuscript with|designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5704063	29113774	MY	2	prepared corneal tissue samples and cage libraries, conducted bioinformatics analyses and the literature search, and prepared figures and tables|wrote the manuscript with|designed the study	prepared corneal tissue samples and cage libraries, conducted bioinformatics analyses and the literature search, and prepared figures and tables	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
5704063	29113774	MY	2	prepared corneal tissue samples and cage libraries, conducted bioinformatics analyses and the literature search, and prepared figures and tables|wrote the manuscript with|designed the study	wrote the manuscript with	Wrote the paper	Writing - Original Draft	YES
5704063	29113774	MY	2	prepared corneal tissue samples and cage libraries, conducted bioinformatics analyses and the literature search, and prepared figures and tables|wrote the manuscript with|designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5704063	29113774	SH	2	prepared cultured cell samples and conducted validation experiments|wrote the manuscript with|designed the study	prepared cultured cell samples and conducted validation experiments	Performed the experiments	Investigation|Validation	YES
5704063	29113774	SH	2	prepared cultured cell samples and conducted validation experiments|wrote the manuscript with|designed the study	wrote the manuscript with	Wrote the paper	Writing - Original Draft	YES
5704063	29113774	SH	2	prepared cultured cell samples and conducted validation experiments|wrote the manuscript with|designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5704063	29113774	SK	2	provided tissue rna samples	provided tissue rna samples	Contributed reagents/materials/analysis tools	Resources	YES
5704063	29113774	YH	2	supervised the project	supervised the project	-	Supervision	YES
4404339	25893518	BC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404339	25893518	BC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404339	25893518	BC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404339	25893518	DAL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404339	25893518	DAL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404339	25893518	DAL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404339	25893518	FAV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404339	25893518	FAV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404339	25893518	FAV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404339	25893518	FAV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404339	25893518	MLA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404339	25893518	MLA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404339	25893518	MLA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404339	25893518	MLA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5237266	28086752	ABS	2	designed the study, performed the research, interpreted the results and wrote the paper	designed the study, performed the research, interpreted the results and wrote the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5237266	28086752	SB	2	designed the study, performed the research, interpreted the results and wrote the paper	designed the study, performed the research, interpreted the results and wrote the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5311843	28209189	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5311843	28209189	CM	2	was guarantor of the study	was guarantor of the study	-	-	NO
5311843	28209189	CS	2	carried out the field work|prepared the study design	carried out the field work	Performed the experiments	Investigation	YES
5311843	28209189	CS	2	carried out the field work|prepared the study design	prepared the study design	Conceived and designed the experiments	Methodology	YES
5311843	28209189	FC	2	carried out the field work|prepared the study design	carried out the field work	Performed the experiments	Investigation	YES
5311843	28209189	FC	2	carried out the field work|prepared the study design	prepared the study design	Conceived and designed the experiments	Methodology	YES
5311843	28209189	GD	2	prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5311843	28209189	GG	2	carried out the field work|prepared the manuscript|prepared the study design	carried out the field work	Performed the experiments	Investigation	YES
5311843	28209189	GG	2	carried out the field work|prepared the manuscript|prepared the study design	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5311843	28209189	GG	2	carried out the field work|prepared the manuscript|prepared the study design	prepared the study design	Conceived and designed the experiments	Methodology	YES
5311843	28209189	MM	2	carried out the statistical analysis|prepared the study design	carried out the statistical analysis	Analyzed the data	Formal analysis	YES
5311843	28209189	MM	2	carried out the statistical analysis|prepared the study design	prepared the study design	Conceived and designed the experiments	Methodology	YES
5311843	28209189	SZ	2	carried out the field work|carried out the statistical analysis|prepared the manuscript|prepared the study design	carried out the field work	Performed the experiments	Investigation	YES
5311843	28209189	SZ	2	carried out the field work|carried out the statistical analysis|prepared the manuscript|prepared the study design	carried out the statistical analysis	Analyzed the data	Formal analysis	YES
5311843	28209189	SZ	2	carried out the field work|carried out the statistical analysis|prepared the manuscript|prepared the study design	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5311843	28209189	SZ	2	carried out the field work|carried out the statistical analysis|prepared the manuscript|prepared the study design	prepared the study design	Conceived and designed the experiments	Methodology	YES
4843097	27158483	Andreas Brandl	1	Study design|Data collection|Data analysis|Writing	Study design	Conceived and designed the experiments	Methodology	YES
4843097	27158483	Andreas Brandl	1	Study design|Data collection|Data analysis|Writing	Data collection	Performed the experiments	Investigation	YES
4843097	27158483	Andreas Brandl	1	Study design|Data collection|Data analysis|Writing	Data analysis	Analyzed the data	Formal analysis	YES
4843097	27158483	Andreas Brandl	1	Study design|Data collection|Data analysis|Writing	Writing	Wrote the paper	-	YES
4843097	27158483	Johann Pratschke	1	Data analysis	Data analysis	Analyzed the data	Formal analysis	YES
4843097	27158483	Reinhard Mittermair	1	Study design	Study design	Conceived and designed the experiments	Methodology	YES
4843097	27158483	Reinhold Kafka-Ritsch	1	Study design|Data analysis	Study design	Conceived and designed the experiments	Methodology	YES
4843097	27158483	Reinhold Kafka-Ritsch	1	Study design|Data analysis	Data analysis	Analyzed the data	Formal analysis	YES
4843097	27158483	Sascha Czipin	1	Data collection	Data collection	Performed the experiments	Investigation	YES
4843097	27158483	Sascha Weiss	1	Data collection	Data collection	Performed the experiments	Investigation	YES
5118379	27873290	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5118379	27873290	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
4843098	27158486	HK	2	did the data collection|did the analysis and interpretation	did the data collection	Performed the experiments	Investigation	YES
4843098	27158486	HK	2	did the data collection|did the analysis and interpretation	did the analysis and interpretation	Analyzed the data	Formal analysis	YES
4843098	27158486	HU	2	contributed to the conception and design|did the data collection|did the writing of the article and the critical revisions	contributed to the conception and design	Conceived and designed the experiments	Conceptualization	YES
4843098	27158486	HU	2	contributed to the conception and design|did the data collection|did the writing of the article and the critical revisions	did the data collection	Performed the experiments	Investigation	YES
4843098	27158486	HU	2	contributed to the conception and design|did the data collection|did the writing of the article and the critical revisions	did the writing of the article and the critical revisions	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4843098	27158486	YN	2	did the data collection|did the analysis and interpretation	did the data collection	Performed the experiments	Investigation	YES
4843098	27158486	YN	2	did the data collection|did the analysis and interpretation	did the analysis and interpretation	Analyzed the data	Formal analysis	YES
5515901	28769964	AK	2	contributed in research and editing of the manuscript	contributed in research and editing of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5515901	28769964	CT	2	contributed to research and supervised mg	contributed to research and supervised mg	-	Supervision	YES
5515901	28769964	KS	2	contributed in research and editing of the manuscript	contributed in research and editing of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5515901	28769964	MV	2	contributed in research and editing of the manuscript	contributed in research and editing of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5515901	28769964	PM	2	are senior author who guided the research and contributed by editing of the manuscript	are senior author who guided the research and contributed by editing of the manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
5515901	28769964	SS	2	was the leading author and contributed to all study related tasks mentioned below	was the leading author and contributed to all study related tasks mentioned below	-	-	NO
5515901	28769964	TB	2	are senior author who guided the research and contributed by editing of the manuscript	are senior author who guided the research and contributed by editing of the manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
5597086	28975901	Deepti Vyas	2	all contributed to the study and survey design	all contributed to the study and survey design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5597086	28975901	Edward Rogan	2	all contributed to the study and survey design	all contributed to the study and survey design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5597086	28975901	Jenana Halilovic	2	all contributed to the study and survey design	all contributed to the study and survey design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5597086	28975901	Marcus Ravnan	2	all contributed to the study and survey design	all contributed to the study and survey design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5597086	28975901	Myo Kyoung Kim	2	all contributed to the study and survey design	all contributed to the study and survey design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5597086	28975901	Suzanne Galal	2	all contributed to the study and survey design	all contributed to the study and survey design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5704068	29100778	AM	1	Conception and design|Assay development and biomarker measurements|Drafting the manuscript for important intellectual content	Conception and design	Conceived and designed the experiments	Conceptualization	YES
5704068	29100778	AM	1	Conception and design|Assay development and biomarker measurements|Drafting the manuscript for important intellectual content	Assay development and biomarker measurements	Performed the experiments	Investigation	YES
5704068	29100778	AM	1	Conception and design|Assay development and biomarker measurements|Drafting the manuscript for important intellectual content	Drafting the manuscript for important intellectual content	Wrote the paper	Writing - Original Draft	YES
5704068	29100778	DL	1	Analysis and interpretation	Analysis and interpretation	Analyzed the data	Formal analysis	YES
5704068	29100778	DML	1	Drafting the manuscript for important intellectual content	Drafting the manuscript for important intellectual content	Wrote the paper	Writing - Original Draft	YES
5704068	29100778	GBS	1	Conception and design|Assay development and biomarker measurements|Analysis and interpretation|Drafting the manuscript for important intellectual content	Conception and design	Conceived and designed the experiments	Conceptualization	YES
5704068	29100778	GBS	1	Conception and design|Assay development and biomarker measurements|Analysis and interpretation|Drafting the manuscript for important intellectual content	Assay development and biomarker measurements	Performed the experiments	Investigation	YES
5704068	29100778	GBS	1	Conception and design|Assay development and biomarker measurements|Analysis and interpretation|Drafting the manuscript for important intellectual content	Analysis and interpretation	Analyzed the data	Formal analysis	YES
5704068	29100778	GBS	1	Conception and design|Assay development and biomarker measurements|Analysis and interpretation|Drafting the manuscript for important intellectual content	Drafting the manuscript for important intellectual content	Wrote the paper	Writing - Original Draft	YES
5704068	29100778	JJ	1	Analysis and interpretation	Analysis and interpretation	Analyzed the data	Formal analysis	YES
5704068	29100778	JLD	1	Analysis and interpretation	Analysis and interpretation	Analyzed the data	Formal analysis	YES
5704068	29100778	JS	1	Analysis and interpretation	Analysis and interpretation	Analyzed the data	Formal analysis	YES
5704068	29100778	KH	1	Assay development and biomarker measurements	Assay development and biomarker measurements	Performed the experiments	Investigation	YES
5704068	29100778	LJ	1	Data acquisition and management	Data acquisition and management	Performed the experiments	Investigation	YES
5704068	29100778	MRS	1	Conception and design|Data acquisition and management|Analysis and interpretation|Drafting the manuscript for important intellectual content	Conception and design	Conceived and designed the experiments	Conceptualization	YES
5704068	29100778	MRS	1	Conception and design|Data acquisition and management|Analysis and interpretation|Drafting the manuscript for important intellectual content	Data acquisition and management	Performed the experiments	Investigation	YES
5704068	29100778	MRS	1	Conception and design|Data acquisition and management|Analysis and interpretation|Drafting the manuscript for important intellectual content	Analysis and interpretation	Analyzed the data	Formal analysis	YES
5704068	29100778	MRS	1	Conception and design|Data acquisition and management|Analysis and interpretation|Drafting the manuscript for important intellectual content	Drafting the manuscript for important intellectual content	Wrote the paper	Writing - Original Draft	YES
5704068	29100778	MW	1	Data acquisition and management|Assay development and biomarker measurements|Analysis and interpretation	Data acquisition and management	Performed the experiments	Investigation	YES
5704068	29100778	MW	1	Data acquisition and management|Assay development and biomarker measurements|Analysis and interpretation	Assay development and biomarker measurements	Performed the experiments	Investigation	YES
5704068	29100778	MW	1	Data acquisition and management|Assay development and biomarker measurements|Analysis and interpretation	Analysis and interpretation	Analyzed the data	Formal analysis	YES
5704068	29100778	NS	1	Assay development and biomarker measurements	Assay development and biomarker measurements	Performed the experiments	Investigation	YES
5704068	29100778	PN	1	Conception and design|Analysis and interpretation|Drafting the manuscript for important intellectual content	Conception and design	Conceived and designed the experiments	Conceptualization	YES
5704068	29100778	PN	1	Conception and design|Analysis and interpretation|Drafting the manuscript for important intellectual content	Analysis and interpretation	Analyzed the data	Formal analysis	YES
5704068	29100778	PN	1	Conception and design|Analysis and interpretation|Drafting the manuscript for important intellectual content	Drafting the manuscript for important intellectual content	Wrote the paper	Writing - Original Draft	YES
5704068	29100778	SB	1	Assay development and biomarker measurements	Assay development and biomarker measurements	Performed the experiments	Investigation	YES
5704068	29100778	WCW	1	Data acquisition and management	Data acquisition and management	Performed the experiments	Investigation	YES
4843099	27158485	All other authors	2	were involved in a supportive or supervisory role as determined by their standing in the authors order	were involved in a supportive or supervisory role as determined by their standing in the authors order	-	Supervision	YES
4843099	27158485	Mr Dolan	2	also contributed a large amount to the paper and acted as the main editor	also contributed a large amount to the paper and acted as the main editor	Wrote the paper	Writing - Review & Editing	YES
4843099	27158485	Mr Luhmann	2	assisted with the took the lead in writing this paper with the	assisted with the took the lead in writing this paper with the	Wrote the paper	Writing - Original Draft	YES
4843099	27158485	Ms Argenti	2	took the lead in writing this paper with the	took the lead in writing this paper with the	Wrote the paper	Writing - Original Draft	YES
4404340	25893977	KM	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404340	25893977	MP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404340	25893977	MP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404340	25893977	MP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404340	25893977	MP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404340	25893977	MP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404340	25893977	RS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404340	25893977	RS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404340	25893977	RS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404340	25893977	SR	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404340	25893977	SR	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5314604	28209198	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5314604	28209198	CGS	2	revised the text and made valuable suggestions	revised the text and made valuable suggestions	Wrote the paper	Writing - Review & Editing	YES
5314604	28209198	FBH	2	wrote the manuscript and designed the artwork	wrote the manuscript and designed the artwork	Conceived and designed the experiments|Wrote the paper	Visualization|Writing - Original Draft	YES
5314604	28209198	JSK	2	revised the text and made valuable suggestions	revised the text and made valuable suggestions	Wrote the paper	Writing - Review & Editing	YES
5314604	28209198	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5237310	28086791	AK	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5237310	28086791	AK	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5237310	28086791	AT	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5237310	28086791	HT	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5237310	28086791	KaI	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5237310	28086791	YN	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4582072	26403636	AB	2	supported and advised on data analysis	supported and advised on data analysis	Analyzed the data	Formal analysis	YES
4582072	26403636	AMB	2	supported the programme implementation|designed and planned the research	supported the programme implementation	Performed the experiments	Investigation	YES
4582072	26403636	AMB	2	supported the programme implementation|designed and planned the research	designed and planned the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
4582072	26403636	All authors	2	commented on design, interpreted the data, critically reviewed the article drafts, and read and approved the final manuscript	commented on design, interpreted the data, critically reviewed the article drafts, and read and approved the final manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
4582072	26403636	BK	2	designed and planned the research|performed the data analysis	designed and planned the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
4582072	26403636	BK	2	designed and planned the research|performed the data analysis	performed the data analysis	Analyzed the data	Formal analysis	YES
4582072	26403636	DC	2	supported the programme implementation|designed and planned the research	supported the programme implementation	Performed the experiments	Investigation	YES
4582072	26403636	DC	2	supported the programme implementation|designed and planned the research	designed and planned the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
4582072	26403636	EG	2	supported the programme implementation	supported the programme implementation	Performed the experiments	Investigation	YES
4582072	26403636	GVC	2	supported the programme implementation|designed and planned the research|supported and advised on data analysis	supported the programme implementation	Performed the experiments	Investigation	YES
4582072	26403636	GVC	2	supported the programme implementation|designed and planned the research|supported and advised on data analysis	designed and planned the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
4582072	26403636	GVC	2	supported the programme implementation|designed and planned the research|supported and advised on data analysis	supported and advised on data analysis	Analyzed the data	Formal analysis	YES
4582072	26403636	KH	2	supported the programme implementation|designed and planned the research	supported the programme implementation	Performed the experiments	Investigation	YES
4582072	26403636	KH	2	supported the programme implementation|designed and planned the research	designed and planned the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
4582072	26403636	KK	2	supported and advised on data analysis	supported and advised on data analysis	Analyzed the data	Formal analysis	YES
4582072	26403636	MS	2	supported and advised on data analysis	supported and advised on data analysis	Analyzed the data	Formal analysis	YES
5515905	28769971	JL	PLoS52	designed the experiment|analyzed the data|assisted with revising the draft manuscript	designed the experiment	Conceived and designed the experiments	Methodology	YES
5515905	28769971	JL	PLoS52	designed the experiment|analyzed the data|assisted with revising the draft manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5515905	28769971	JL	PLoS52	designed the experiment|analyzed the data|assisted with revising the draft manuscript	assisted with revising the draft manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5515905	28769971	JT	PLoS52	carried out the field work	carried out the field work	Performed the experiments	Investigation	YES
5515905	28769971	YG	PLoS52	carried out the field work|analyzed the data|wrote the manuscript	carried out the field work	Performed the experiments	Investigation	YES
5515905	28769971	YG	PLoS52	carried out the field work|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5515905	28769971	YG	PLoS52	carried out the field work|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5515905	28769971	YP	PLoS52	carried out the field work	carried out the field work	Performed the experiments	Investigation	YES
5597087	28975902	Hana Morrissey	4	Validation of data interpretation and editorial input of publication by	Validation of data interpretation and editorial input of publication by	Performed the experiments|Analyzed the data	Formal analysis|Validation	YES
5597087	28975902	Mary Bushell	4	data interpretation and write up by	data interpretation and write up by	Analyzed the data|Wrote the paper	Formal analysis	YES
5597087	28975902	Patrick Ball	4	Validation of data interpretation and editorial input of publication by	Validation of data interpretation and editorial input of publication by	Performed the experiments|Analyzed the data	Formal analysis|Validation	YES
5127918	27900735	AO	2	equally contributed to this manuscript	equally contributed to this manuscript	-	-	NO
5127918	27900735	Both authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5127918	27900735	PG	2	equally contributed to this manuscript	equally contributed to this manuscript	-	-	NO
5704071	29056541	Hirotoshi Takiyama	7	Collection and assembly of data, and final approval of the article	Collection and assembly of data, and final approval of the article	Performed the experiments	Investigation	YES
5704071	29056541	Kazuharu Aoyama	7	Developing the convolutional neural networks, performing the tests of convolutional neural networks, describing the receiver operating curve, drafting the article (part of the convolutional neural networks in the methods section), and final approval of the article	Developing the convolutional neural networks, performing the tests of convolutional neural networks, describing the receiver operating curve, drafting the article (part of the convolutional neural networks in the methods section), and final approval of the article	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Methodology|Software|Writing - Original Draft	YES
5704071	29056541	Keigo Matsuo	7	Critical revision of the article for important intellectual content, and final approval of the article	Critical revision of the article for important intellectual content, and final approval of the article	Wrote the paper	Writing - Review & Editing	YES
5704071	29056541	Motoi Miura	7	Collection and assembly of data, and final approval of the article	Collection and assembly of data, and final approval of the article	Performed the experiments	Investigation	YES
5704071	29056541	Satoki Shichijo	7	Interpretation of data, drafting of the article, and final approval of the article	Interpretation of data, drafting of the article, and final approval of the article	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5704071	29056541	Shuhei Nomura	7	Analysis and interpretation of data, drafting of the article, and final approval of the article	Analysis and interpretation of data, drafting of the article, and final approval of the article	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5704071	29056541	Soichiro Ishihara	7	Critical revision of the article for important intellectual content, and final approval of the article	Critical revision of the article for important intellectual content, and final approval of the article	Wrote the paper	Writing - Review & Editing	YES
5704071	29056541	Takahide Shinagawa	7	Collection and assembly of data, and final approval of the article	Collection and assembly of data, and final approval of the article	Performed the experiments	Investigation	YES
5704071	29056541	Tetsuya Tanimoto	7	Critical revision of the article for important intellectual content, and final approval of the article	Critical revision of the article for important intellectual content, and final approval of the article	Wrote the paper	Writing - Review & Editing	YES
5704071	29056541	Tomohiro Tada	7	Conception and design of the study, and final approval of the article	Conception and design of the study, and final approval of the article	Conceived and designed the experiments	Conceptualization|Methodology	YES
5704071	29056541	Yoshitaka Nishikawa	7	Critical revision of the article for important intellectual content, and final approval of the article	Critical revision of the article for important intellectual content, and final approval of the article	Wrote the paper	Writing - Review & Editing	YES
4584214	26411694	AB	PLoS52	conceived and designed the study|analyzed the data	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4584214	26411694	AB	PLoS52	conceived and designed the study|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
4584214	26411694	All authors	PLoS52	interpreted the data and critically reviewed the manuscript	interpreted the data and critically reviewed the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4584214	26411694	JC	PLoS52	was involved in collecting the data	was involved in collecting the data	Performed the experiments	Investigation	YES
4584214	26411694	RW	PLoS52	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4584214	26411694	SH	PLoS52	conceived and designed the study|analyzed the data|wrote the first draft	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4584214	26411694	SH	PLoS52	conceived and designed the study|analyzed the data|wrote the first draft	analyzed the data	Analyzed the data	Formal analysis	YES
4584214	26411694	SH	PLoS52	conceived and designed the study|analyzed the data|wrote the first draft	wrote the first draft	Wrote the paper	Writing - Original Draft	YES
4404341	25894555	CD	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Literature search	Performed the experiments	Performed the experiments	Investigation	YES
4404341	25894555	CD	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Literature search	Analyzed the data	Analyzed the data	Formal analysis	YES
4404341	25894555	CD	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Literature search	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404341	25894555	CD	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Literature search	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404341	25894555	CD	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Literature search	Literature search	-	Formal analysis	YES
4404341	25894555	GL	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404341	25894555	HL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404341	25894555	HL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404341	25894555	HL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404341	25894555	HL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404341	25894555	JD	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404341	25894555	JD	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404341	25894555	JD	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404341	25894555	JD	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404341	25894555	LP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404341	25894555	LP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404341	25894555	LP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404341	25894555	XX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Literature search	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404341	25894555	XX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Literature search	Performed the experiments	Performed the experiments	Investigation	YES
4404341	25894555	XX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Literature search	Analyzed the data	Analyzed the data	Formal analysis	YES
4404341	25894555	XX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Literature search	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404341	25894555	XX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Literature search	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404341	25894555	XX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Literature search	Literature search	-	Formal analysis	YES
4404341	25894555	XY	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404341	25894555	XY	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404341	25894555	XY	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404341	25894555	ZC	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5336692	28257647	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5336692	28257647	DAC	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5336692	28257647	HAS	2	supervised patient care and data entry|revised the manuscript	supervised patient care and data entry	Performed the experiments|Analyzed the data	Data curation|Investigation|Supervision	YES
5336692	28257647	HAS	2	supervised patient care and data entry|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5336692	28257647	JH	2	performed the statistical analysis and wrote the first draft	performed the statistical analysis and wrote the first draft	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5336692	28257647	MAB	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5336692	28257647	MMK	2	supervised patient care and data entry	supervised patient care and data entry	Performed the experiments|Analyzed the data	Data curation|Investigation|Supervision	YES
5336692	28257647	TTK	2	supervised patient care and data entry	supervised patient care and data entry	Performed the experiments|Analyzed the data	Data curation|Investigation|Supervision	YES
5336692	28257647	ZWH	2	assisted with data entry and statistical analysis	assisted with data entry and statistical analysis	Analyzed the data	Data curation|Formal analysis	YES
5597088	28975903	J Sahm	2	consensus was achieved on which key results should be displayed	consensus was achieved on which key results should be displayed	-	-	NO
5237495	28088189	LAKA	2	designed the solution|implemented the solution and conducted the experiments|wrote the manuscript	designed the solution	Conceived and designed the experiments	-	YES
5237495	28088189	LAKA	2	designed the solution|implemented the solution and conducted the experiments|wrote the manuscript	implemented the solution and conducted the experiments	Performed the experiments	Investigation	YES
5237495	28088189	LAKA	2	designed the solution|implemented the solution and conducted the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5237495	28088189	SPP	2	conceived the study|designed the solution|wrote the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5237495	28088189	SPP	2	conceived the study|designed the solution|wrote the manuscript	designed the solution	Conceived and designed the experiments	-	YES
5237495	28088189	SPP	2	conceived the study|designed the solution|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4843101	27158484	David Bolus	2	all helped with the design of the study	all helped with the design of the study	Conceived and designed the experiments	Methodology	YES
4843101	27158484	Desiree Morgan	2	all helped with the design of the study	all helped with the design of the study	Conceived and designed the experiments	Methodology	YES
4843101	27158484	Lincoln Berland	2	all helped with the design of the study	all helped with the design of the study	Conceived and designed the experiments	Methodology	YES
4843101	27158484	Michael Yester	2	all helped with the design of the study	all helped with the design of the study	Conceived and designed the experiments	Methodology	YES
4843101	27158484	PI	2	lead author	lead author	-	-	NO
5145893	27858347	All authors	1	Acquisition or analysis of data|Critical revision of the article for important intellectual content	Acquisition or analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5145893	27858347	All authors	1	Acquisition or analysis of data|Critical revision of the article for important intellectual content	Critical revision of the article for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5145893	27858347	NES	1	Conception and design|Drafting the article	Conception and design	Conceived and designed the experiments	Conceptualization	YES
5145893	27858347	NES	1	Conception and design|Drafting the article	Drafting the article	Wrote the paper	Writing - Original Draft	YES
5145893	27858347	OAA	1	Conception and design|Drafting the article	Conception and design	Conceived and designed the experiments	Conceptualization	YES
5145893	27858347	OAA	1	Conception and design|Drafting the article	Drafting the article	Wrote the paper	Writing - Original Draft	YES
5145893	27858347	OS	1	Conception and design	Conception and design	Conceived and designed the experiments	Conceptualization	YES
5515906	28769975	AR	PLoS52	designed the study|coordinated the data collection|analyzed the data|prepared the first draft of manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5515906	28769975	AR	PLoS52	designed the study|coordinated the data collection|analyzed the data|prepared the first draft of manuscript	coordinated the data collection	Performed the experiments	Investigation|Project administration	YES
5515906	28769975	AR	PLoS52	designed the study|coordinated the data collection|analyzed the data|prepared the first draft of manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5515906	28769975	AR	PLoS52	designed the study|coordinated the data collection|analyzed the data|prepared the first draft of manuscript	prepared the first draft of manuscript	Wrote the paper	Writing - Original Draft	YES
5515906	28769975	GB	PLoS52	designed the study|prepared the first draft of manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5515906	28769975	GB	PLoS52	designed the study|prepared the first draft of manuscript	prepared the first draft of manuscript	Wrote the paper	Writing - Original Draft	YES
5515906	28769975	LM	PLoS52	coordinated the data collection	coordinated the data collection	Performed the experiments	Investigation|Project administration	YES
5515906	28769975	MM	PLoS52	supported the design and analysis	supported the design and analysis	Conceived and designed the experiments	-	YES
5515906	28769975	RP	PLoS52	supported the design and analysis	supported the design and analysis	Conceived and designed the experiments	-	YES
5515906	28769975	all authors	PLoS52	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4590343	26426197	ALL	2	performed the analysis and interpretation of data|critically revised the manuscript for intellectual content	performed the analysis and interpretation of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4590343	26426197	ALL	2	performed the analysis and interpretation of data|critically revised the manuscript for intellectual content	critically revised the manuscript for intellectual content	Wrote the paper	Writing - Review & Editing	YES
4590343	26426197	BLH	2	performed the analysis and interpretation of data|critically revised the manuscript for intellectual content	performed the analysis and interpretation of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4590343	26426197	BLH	2	performed the analysis and interpretation of data|critically revised the manuscript for intellectual content	critically revised the manuscript for intellectual content	Wrote the paper	Writing - Review & Editing	YES
4590343	26426197	CE	2	performed the analysis and interpretation of data|critically revised the manuscript for intellectual content	performed the analysis and interpretation of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4590343	26426197	CE	2	performed the analysis and interpretation of data|critically revised the manuscript for intellectual content	critically revised the manuscript for intellectual content	Wrote the paper	Writing - Review & Editing	YES
4590343	26426197	CM	2	conducted the clinical assessments	conducted the clinical assessments	Performed the experiments	Investigation	YES
4590343	26426197	CW	2	performed the analysis and interpretation of data|critically revised the manuscript for intellectual content	performed the analysis and interpretation of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4590343	26426197	CW	2	performed the analysis and interpretation of data|critically revised the manuscript for intellectual content	critically revised the manuscript for intellectual content	Wrote the paper	Writing - Review & Editing	YES
4590343	26426197	DdaS	2	conducted the clinical assessments	conducted the clinical assessments	Performed the experiments	Investigation	YES
4590343	26426197	FGC	2	conducted the clinical assessments	conducted the clinical assessments	Performed the experiments	Investigation	YES
4590343	26426197	LO	2	performed the analysis and interpretation of data|critically revised the manuscript for intellectual content	performed the analysis and interpretation of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4590343	26426197	LO	2	performed the analysis and interpretation of data|critically revised the manuscript for intellectual content	critically revised the manuscript for intellectual content	Wrote the paper	Writing - Review & Editing	YES
4590343	26426197	SJ	2	conceived the study|performed the analysis and interpretation of data	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4590343	26426197	SJ	2	conceived the study|performed the analysis and interpretation of data	performed the analysis and interpretation of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5341455	28270215	All authors	2	read and approved the manuscript	read and approved the manuscript	-	-	NO
5341455	28270215	EL	2	recruited study subjects, collected samples and demographic data	recruited study subjects, collected samples and demographic data	Performed the experiments	Investigation	YES
5341455	28270215	GG	2	analyzed the data and prepared the manuscript with contributions from all the authors	analyzed the data and prepared the manuscript with contributions from all the authors	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5341455	28270215	HKK	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5341455	28270215	LM	2	performed the laboratory analyses	performed the laboratory analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5341455	28270215	PB	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5341455	28270215	RNN	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5341455	28270215	TM	2	performed the laboratory analyses	performed the laboratory analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4843102	27158487	Masahiro Kimura	7	study design, data collection, data analysis, writing	study design, data collection, data analysis, writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology	YES
4843102	27158487	Yukio Terashita	7	data collection	data collection	Performed the experiments	Investigation	YES
4404342	25893404	KJM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404342	25893404	KJM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404342	25893404	KJM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404342	25893404	KJM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404342	25893404	LLT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404342	25893404	LLT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404342	25893404	LLT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404342	25893404	LLT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404342	25893404	LLT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5828370	29269042	B.B.	2	designed experiments	designed experiments	Conceived and designed the experiments	Methodology	YES
5828370	29269042	C.F.	2	designed experiments	designed experiments	Conceived and designed the experiments	Methodology	YES
5828370	29269042	E.M.	2	interpreted the data|wrote the manuscript	interpreted the data	Analyzed the data	Formal analysis	YES
5828370	29269042	E.M.	2	interpreted the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5828370	29269042	H.M.	2	designed experiments|interpreted the data	designed experiments	Conceived and designed the experiments	Methodology	YES
5828370	29269042	H.M.	2	designed experiments|interpreted the data	interpreted the data	Analyzed the data	Formal analysis	YES
5828370	29269042	M.P.	2	designed experiments|interpreted the data|wrote the manuscript	designed experiments	Conceived and designed the experiments	Methodology	YES
5828370	29269042	M.P.	2	designed experiments|interpreted the data|wrote the manuscript	interpreted the data	Analyzed the data	Formal analysis	YES
5828370	29269042	M.P.	2	designed experiments|interpreted the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5828370	29269042	O.S.	2	designed experiments|interpreted the data|wrote the manuscript	designed experiments	Conceived and designed the experiments	Methodology	YES
5828370	29269042	O.S.	2	designed experiments|interpreted the data|wrote the manuscript	interpreted the data	Analyzed the data	Formal analysis	YES
5828370	29269042	O.S.	2	designed experiments|interpreted the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5828370	29269042	R.I.	2	designed experiments|interpreted the data|wrote the manuscript	designed experiments	Conceived and designed the experiments	Methodology	YES
5828370	29269042	R.I.	2	designed experiments|interpreted the data|wrote the manuscript	interpreted the data	Analyzed the data	Formal analysis	YES
5828370	29269042	R.I.	2	designed experiments|interpreted the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5828370	29269042	S.F.	2	designed experiments	designed experiments	Conceived and designed the experiments	Methodology	YES
5828370	29269042	S.H.	2	designed experiments	designed experiments	Conceived and designed the experiments	Methodology	YES
5828370	29269042	T.D.	2	designed experiments|interpreted the data|wrote the manuscript	designed experiments	Conceived and designed the experiments	Methodology	YES
5828370	29269042	T.D.	2	designed experiments|interpreted the data|wrote the manuscript	interpreted the data	Analyzed the data	Formal analysis	YES
5828370	29269042	T.D.	2	designed experiments|interpreted the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5828370	29269042	V.E.	2	designed experiments|interpreted the data	designed experiments	Conceived and designed the experiments	Methodology	YES
5828370	29269042	V.E.	2	designed experiments|interpreted the data	interpreted the data	Analyzed the data	Formal analysis	YES
5597099	28975899	Eva Martinez	2	collaboratively conceived of the original idea and jointly wrote the original version of this manuscript	collaboratively conceived of the original idea and jointly wrote the original version of this manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5597099	28975899	Roland Dickerson	2	collaboratively conceived of the original idea and jointly wrote the original version of this manuscript	collaboratively conceived of the original idea and jointly wrote the original version of this manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4592848	26434780	G. All	2	authors contributed to interpretation of results and critically reviewed and edited the manuscript	authors contributed to interpretation of results and critically reviewed and edited the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4592848	26434780	MS	2	conceived and designed the study|analyzed and interpreted data	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4592848	26434780	MS	2	conceived and designed the study|analyzed and interpreted data	analyzed and interpreted data	Analyzed the data	Formal analysis	YES
4592848	26434780	MVM	2	conceived and designed the study|analyzed and interpreted data	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4592848	26434780	MVM	2	conceived and designed the study|analyzed and interpreted data	analyzed and interpreted data	Analyzed the data	Formal analysis	YES
5237518	28088192	LK	2	analyzed the sequence data and contributed to writing	analyzed the sequence data and contributed to writing	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation	YES
5237518	28088192	MFS	2	contributed to data interpretation and writing	contributed to data interpretation and writing	Analyzed the data|Wrote the paper	Formal analysis	YES
5237518	28088192	PM	2	wrote the paper and interpreted the data	wrote the paper and interpreted the data	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5237518	28088192	PMS	2	conducted the experiment and contributed to data interpretation and writing	conducted the experiment and contributed to data interpretation and writing	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation	YES
5237518	28088192	VL	2	conceived the experiment and contributed to data interpretation and writing	conceived the experiment and contributed to data interpretation and writing	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis	YES
5348890	28293270	AW	2	contributed to the design of the study, analyzed the data, assisted with the interpretation of the data and revised the draft critically	contributed to the design of the study, analyzed the data, assisted with the interpretation of the data and revised the draft critically	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5348890	28293270	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5348890	28293270	CM	2	supervised the research process, assisted with interpretation of the data, revised the draft critically and gave final approval of the version to be published	supervised the research process, assisted with interpretation of the data, revised the draft critically and gave final approval of the version to be published	Analyzed the data|Wrote the paper	Data curation|Formal analysis|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
5348890	28293270	CN	2	assisted in the design of the study, supervised the work, contributed to the analysis of data, assisted with the interpretation of the data, revised the draft critically and gave final approval of the version to be published	assisted in the design of the study, supervised the work, contributed to the analysis of data, assisted with the interpretation of the data, revised the draft critically and gave final approval of the version to be published	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
5348890	28293270	GM	2	contributed to the design of the study, analyzed the data, assisted with the interpretation of the data and revised the draft critically	contributed to the design of the study, analyzed the data, assisted with the interpretation of the data and revised the draft critically	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5348890	28293270	LW	2	analyzed the data and revised the draft critically	analyzed the data and revised the draft critically	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5348890	28293270	TM	2	was responsible for the conception of the study, its design, data collection, drafting of the manuscript and analysis of data	was responsible for the conception of the study, its design, data collection, drafting of the manuscript and analysis of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4846821	27158482	FATAS	7	data collections. Juan	data collections. Juan	Performed the experiments	Investigation	YES
4846821	27158482	Fabrizio Ana Maria	7	data collections data analysis, writing	data collections data analysis, writing	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation	YES
4846821	27158482	Jose Antonio	7	data collections. Juan	data collections. Juan	Performed the experiments	Investigation	YES
4846821	27158482	MARIN	7	data collections, data analysis. Francis	data collections, data analysis. Francis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4846821	27158482	MATOS-AZEVEDO	7	data collections data analysis, writing	data collections data analysis, writing	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation	YES
4846821	27158482	NAVARRO	7	study design, data analysis. Cristobal	study design, data analysis. Cristobal	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
4846821	27158482	PANARO	7	study design, data collections, data analysis, writing	study design, data collections, data analysis, writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology	YES
4846821	27158482	ZARAGOZA-FERNANDEZ	7	study design, data analysis, Writing	study design, data analysis, Writing	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology	YES
5250624	28108944	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5250624	28108944	EM	2	included all participants and provided the data necessary for our analysis	included all participants and provided the data necessary for our analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5250624	28108944	GJLJS	2	undertook the statistical analyses and managed the literature searches and analyses, and wrote the draft of the manuscript	undertook the statistical analyses and managed the literature searches and analyses, and wrote the draft of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5250624	28108944	HAD	2	designed the study and wrote the protocol|assessed thyroid function	designed the study and wrote the protocol	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5250624	28108944	HAD	2	designed the study and wrote the protocol|assessed thyroid function	assessed thyroid function	-	-	NO
5250624	28108944	LW	2	assisted the preparation and proofreading of the manuscript, and all authors contributed	assisted the preparation and proofreading of the manuscript, and all authors contributed	Wrote the paper	Writing - Original Draft	YES
5250624	28108944	MHJH	2	designed the study and wrote the protocol|included all participants and provided the data necessary for our analysis	designed the study and wrote the protocol	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5250624	28108944	MHJH	2	designed the study and wrote the protocol|included all participants and provided the data necessary for our analysis	included all participants and provided the data necessary for our analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5250624	28108944	RB	2	supervised the statistical analysis	supervised the statistical analysis	Analyzed the data	Formal analysis|Supervision	YES
5250624	28108944	RV	2	included all participants and provided the data necessary for our analysis	included all participants and provided the data necessary for our analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5250624	28108944	SK	2	included all participants and provided the data necessary for our analysis	included all participants and provided the data necessary for our analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5250624	28108944	WAN	2	designed the study and wrote the protocol	designed the study and wrote the protocol	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4404343	25894585	BS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404343	25894585	BS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404343	25894585	BS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404343	25894585	BS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404343	25894585	MR	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404343	25894585	MR	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404343	25894585	PS	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404343	25894585	PS	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404343	25894585	PW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404343	25894585	PW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404343	25894585	PW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404343	25894585	RS	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404343	25894585	RS	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404343	25894585	SC	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404343	25894585	SC	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404343	25894585	SF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404343	25894585	SF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404343	25894585	SF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404343	25894585	SW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404343	25894585	SW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404343	25894585	SW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404343	25894585	SW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5351163	28292305	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5351163	28292305	DN	2	extracted and collated data for analysis	extracted and collated data for analysis	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5351163	28292305	HD	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5351163	28292305	LN	2	designed the study|with contributions from all authors	designed the study	Conceived and designed the experiments	Methodology	YES
5351163	28292305	LN	2	designed the study|with contributions from all authors	with contributions from all authors	-	-	NO
5351163	28292305	PB	2	designed the study|extracted and collated data for analysis|conducted data analysis	designed the study	Conceived and designed the experiments	Methodology	YES
5351163	28292305	PB	2	designed the study|extracted and collated data for analysis|conducted data analysis	extracted and collated data for analysis	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5351163	28292305	PB	2	designed the study|extracted and collated data for analysis|conducted data analysis	conducted data analysis	Analyzed the data	Formal analysis	YES
5351163	28292305	RPR	2	designed the study|with contributions from all authors	designed the study	Conceived and designed the experiments	Methodology	YES
5351163	28292305	RPR	2	designed the study|with contributions from all authors	with contributions from all authors	-	-	NO
5351163	28292305	SR	2	with contributions from all authors	with contributions from all authors	-	-	NO
5351163	28292305	SW	2	conducted data analysis	conducted data analysis	Analyzed the data	Formal analysis	YES
5351163	28292305	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5515915	28769972	LB	2	contributed substantially to the conception and design of the work|performed all molecular work and genotype scoring|interpretation of data|drafted the text|approved the version to be published|agreed to be accountable for all aspects of the work	contributed substantially to the conception and design of the work	Conceived and designed the experiments	Conceptualization	YES
5515915	28769972	LB	2	contributed substantially to the conception and design of the work|performed all molecular work and genotype scoring|interpretation of data|drafted the text|approved the version to be published|agreed to be accountable for all aspects of the work	performed all molecular work and genotype scoring	Performed the experiments	Investigation	YES
5515915	28769972	LB	2	contributed substantially to the conception and design of the work|performed all molecular work and genotype scoring|interpretation of data|drafted the text|approved the version to be published|agreed to be accountable for all aspects of the work	interpretation of data	Analyzed the data	Formal analysis	YES
5515915	28769972	LB	2	contributed substantially to the conception and design of the work|performed all molecular work and genotype scoring|interpretation of data|drafted the text|approved the version to be published|agreed to be accountable for all aspects of the work	drafted the text	Wrote the paper	Writing - Original Draft	YES
5515915	28769972	LB	2	contributed substantially to the conception and design of the work|performed all molecular work and genotype scoring|interpretation of data|drafted the text|approved the version to be published|agreed to be accountable for all aspects of the work	approved the version to be published	-	-	NO
5515915	28769972	LB	2	contributed substantially to the conception and design of the work|performed all molecular work and genotype scoring|interpretation of data|drafted the text|approved the version to be published|agreed to be accountable for all aspects of the work	agreed to be accountable for all aspects of the work	-	-	NO
5515915	28769972	LN	2	contributed substantially to the conception and design of the work|contributed to plant material collection|interpretation of data|drafted the text|approved the version to be published|agreed to be accountable for all aspects of the work	contributed substantially to the conception and design of the work	Conceived and designed the experiments	Conceptualization	YES
5515915	28769972	LN	2	contributed substantially to the conception and design of the work|contributed to plant material collection|interpretation of data|drafted the text|approved the version to be published|agreed to be accountable for all aspects of the work	contributed to plant material collection	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5515915	28769972	LN	2	contributed substantially to the conception and design of the work|contributed to plant material collection|interpretation of data|drafted the text|approved the version to be published|agreed to be accountable for all aspects of the work	interpretation of data	Analyzed the data	Formal analysis	YES
5515915	28769972	LN	2	contributed substantially to the conception and design of the work|contributed to plant material collection|interpretation of data|drafted the text|approved the version to be published|agreed to be accountable for all aspects of the work	drafted the text	Wrote the paper	Writing - Original Draft	YES
5515915	28769972	LN	2	contributed substantially to the conception and design of the work|contributed to plant material collection|interpretation of data|drafted the text|approved the version to be published|agreed to be accountable for all aspects of the work	approved the version to be published	-	-	NO
5515915	28769972	LN	2	contributed substantially to the conception and design of the work|contributed to plant material collection|interpretation of data|drafted the text|approved the version to be published|agreed to be accountable for all aspects of the work	agreed to be accountable for all aspects of the work	-	-	NO
5515915	28769972	LR	2	contributed substantially to the conception and design of the work|contributed to plant material collection|interpretation of data|drafted the text|approved the version to be published|agreed to be accountable for all aspects of the work	contributed substantially to the conception and design of the work	Conceived and designed the experiments	Conceptualization	YES
5515915	28769972	LR	2	contributed substantially to the conception and design of the work|contributed to plant material collection|interpretation of data|drafted the text|approved the version to be published|agreed to be accountable for all aspects of the work	contributed to plant material collection	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5515915	28769972	LR	2	contributed substantially to the conception and design of the work|contributed to plant material collection|interpretation of data|drafted the text|approved the version to be published|agreed to be accountable for all aspects of the work	interpretation of data	Analyzed the data	Formal analysis	YES
5515915	28769972	LR	2	contributed substantially to the conception and design of the work|contributed to plant material collection|interpretation of data|drafted the text|approved the version to be published|agreed to be accountable for all aspects of the work	drafted the text	Wrote the paper	Writing - Original Draft	YES
5515915	28769972	LR	2	contributed substantially to the conception and design of the work|contributed to plant material collection|interpretation of data|drafted the text|approved the version to be published|agreed to be accountable for all aspects of the work	approved the version to be published	-	-	NO
5515915	28769972	LR	2	contributed substantially to the conception and design of the work|contributed to plant material collection|interpretation of data|drafted the text|approved the version to be published|agreed to be accountable for all aspects of the work	agreed to be accountable for all aspects of the work	-	-	NO
5515915	28769972	MB	2	contributed substantially to the conception and design of the work|drafted the text|approved the version to be published|agreed to be accountable for all aspects of the work	contributed substantially to the conception and design of the work	Conceived and designed the experiments	Conceptualization	YES
5515915	28769972	MB	2	contributed substantially to the conception and design of the work|drafted the text|approved the version to be published|agreed to be accountable for all aspects of the work	drafted the text	Wrote the paper	Writing - Original Draft	YES
5515915	28769972	MB	2	contributed substantially to the conception and design of the work|drafted the text|approved the version to be published|agreed to be accountable for all aspects of the work	approved the version to be published	-	-	NO
5515915	28769972	MB	2	contributed substantially to the conception and design of the work|drafted the text|approved the version to be published|agreed to be accountable for all aspects of the work	agreed to be accountable for all aspects of the work	-	-	NO
5515915	28769972	PP	2	contributed substantially to the conception and design of the work|drafted the text|approved the version to be published|agreed to be accountable for all aspects of the work	contributed substantially to the conception and design of the work	Conceived and designed the experiments	Conceptualization	YES
5515915	28769972	PP	2	contributed substantially to the conception and design of the work|drafted the text|approved the version to be published|agreed to be accountable for all aspects of the work	drafted the text	Wrote the paper	Writing - Original Draft	YES
5515915	28769972	PP	2	contributed substantially to the conception and design of the work|drafted the text|approved the version to be published|agreed to be accountable for all aspects of the work	approved the version to be published	-	-	NO
5515915	28769972	PP	2	contributed substantially to the conception and design of the work|drafted the text|approved the version to be published|agreed to be accountable for all aspects of the work	agreed to be accountable for all aspects of the work	-	-	NO
5515915	28769972	RM	2	contributed substantially to the conception and design of the work|contributed to plant material collection|performed all molecular work and genotype scoring|interpretation of data|drafted the text|approved the version to be published|agreed to be accountable for all aspects of the work	contributed substantially to the conception and design of the work	Conceived and designed the experiments	Conceptualization	YES
5515915	28769972	RM	2	contributed substantially to the conception and design of the work|contributed to plant material collection|performed all molecular work and genotype scoring|interpretation of data|drafted the text|approved the version to be published|agreed to be accountable for all aspects of the work	contributed to plant material collection	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5515915	28769972	RM	2	contributed substantially to the conception and design of the work|contributed to plant material collection|performed all molecular work and genotype scoring|interpretation of data|drafted the text|approved the version to be published|agreed to be accountable for all aspects of the work	performed all molecular work and genotype scoring	Performed the experiments	Investigation	YES
5515915	28769972	RM	2	contributed substantially to the conception and design of the work|contributed to plant material collection|performed all molecular work and genotype scoring|interpretation of data|drafted the text|approved the version to be published|agreed to be accountable for all aspects of the work	interpretation of data	Analyzed the data	Formal analysis	YES
5515915	28769972	RM	2	contributed substantially to the conception and design of the work|contributed to plant material collection|performed all molecular work and genotype scoring|interpretation of data|drafted the text|approved the version to be published|agreed to be accountable for all aspects of the work	drafted the text	Wrote the paper	Writing - Original Draft	YES
5515915	28769972	RM	2	contributed substantially to the conception and design of the work|contributed to plant material collection|performed all molecular work and genotype scoring|interpretation of data|drafted the text|approved the version to be published|agreed to be accountable for all aspects of the work	approved the version to be published	-	-	NO
5515915	28769972	RM	2	contributed substantially to the conception and design of the work|contributed to plant material collection|performed all molecular work and genotype scoring|interpretation of data|drafted the text|approved the version to be published|agreed to be accountable for all aspects of the work	agreed to be accountable for all aspects of the work	-	-	NO
5515915	28769972	SM	2	contributed substantially to the conception and design of the work|contributed to plant material collection|performed all molecular work and genotype scoring|interpretation of data|drafted the text|approved the version to be published|agreed to be accountable for all aspects of the work	contributed substantially to the conception and design of the work	Conceived and designed the experiments	Conceptualization	YES
5515915	28769972	SM	2	contributed substantially to the conception and design of the work|contributed to plant material collection|performed all molecular work and genotype scoring|interpretation of data|drafted the text|approved the version to be published|agreed to be accountable for all aspects of the work	contributed to plant material collection	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5515915	28769972	SM	2	contributed substantially to the conception and design of the work|contributed to plant material collection|performed all molecular work and genotype scoring|interpretation of data|drafted the text|approved the version to be published|agreed to be accountable for all aspects of the work	performed all molecular work and genotype scoring	Performed the experiments	Investigation	YES
5515915	28769972	SM	2	contributed substantially to the conception and design of the work|contributed to plant material collection|performed all molecular work and genotype scoring|interpretation of data|drafted the text|approved the version to be published|agreed to be accountable for all aspects of the work	interpretation of data	Analyzed the data	Formal analysis	YES
5515915	28769972	SM	2	contributed substantially to the conception and design of the work|contributed to plant material collection|performed all molecular work and genotype scoring|interpretation of data|drafted the text|approved the version to be published|agreed to be accountable for all aspects of the work	drafted the text	Wrote the paper	Writing - Original Draft	YES
5515915	28769972	SM	2	contributed substantially to the conception and design of the work|contributed to plant material collection|performed all molecular work and genotype scoring|interpretation of data|drafted the text|approved the version to be published|agreed to be accountable for all aspects of the work	approved the version to be published	-	-	NO
5515915	28769972	SM	2	contributed substantially to the conception and design of the work|contributed to plant material collection|performed all molecular work and genotype scoring|interpretation of data|drafted the text|approved the version to be published|agreed to be accountable for all aspects of the work	agreed to be accountable for all aspects of the work	-	-	NO
5515915	28769972	SP	2	contributed substantially to the conception and design of the work|contributed to plant material collection|interpretation of data|drafted the text|approved the version to be published|agreed to be accountable for all aspects of the work	contributed substantially to the conception and design of the work	Conceived and designed the experiments	Conceptualization	YES
5515915	28769972	SP	2	contributed substantially to the conception and design of the work|contributed to plant material collection|interpretation of data|drafted the text|approved the version to be published|agreed to be accountable for all aspects of the work	contributed to plant material collection	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5515915	28769972	SP	2	contributed substantially to the conception and design of the work|contributed to plant material collection|interpretation of data|drafted the text|approved the version to be published|agreed to be accountable for all aspects of the work	interpretation of data	Analyzed the data	Formal analysis	YES
5515915	28769972	SP	2	contributed substantially to the conception and design of the work|contributed to plant material collection|interpretation of data|drafted the text|approved the version to be published|agreed to be accountable for all aspects of the work	drafted the text	Wrote the paper	Writing - Original Draft	YES
5515915	28769972	SP	2	contributed substantially to the conception and design of the work|contributed to plant material collection|interpretation of data|drafted the text|approved the version to be published|agreed to be accountable for all aspects of the work	approved the version to be published	-	-	NO
5515915	28769972	SP	2	contributed substantially to the conception and design of the work|contributed to plant material collection|interpretation of data|drafted the text|approved the version to be published|agreed to be accountable for all aspects of the work	agreed to be accountable for all aspects of the work	-	-	NO
5237526	28088165	AFM	2	participated in the analysis and in the writing of the manuscript	participated in the analysis and in the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5237526	28088165	ALQ	2	designed the experiments, performed gdna extractions and qpcr assays, analyzed the data and drafted the manuscript	designed the experiments, performed gdna extractions and qpcr assays, analyzed the data and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5237526	28088165	CL	2	participated in the analysis and in the writing of the manuscript|performed the phenotypic macroarray assays|performed the malonate utilization assay|performed eckhardt gel analyzes	participated in the analysis and in the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5237526	28088165	CL	2	participated in the analysis and in the writing of the manuscript|performed the phenotypic macroarray assays|performed the malonate utilization assay|performed eckhardt gel analyzes	performed the phenotypic macroarray assays	Performed the experiments	Investigation	YES
5237526	28088165	CL	2	participated in the analysis and in the writing of the manuscript|performed the phenotypic macroarray assays|performed the malonate utilization assay|performed eckhardt gel analyzes	performed the malonate utilization assay	Performed the experiments	Investigation	YES
5237526	28088165	CL	2	participated in the analysis and in the writing of the manuscript|performed the phenotypic macroarray assays|performed the malonate utilization assay|performed eckhardt gel analyzes	performed eckhardt gel analyzes	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5237526	28088165	DC	2	performed eckhardt gel analyzes	performed eckhardt gel analyzes	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5237526	28088165	DS	2	prepared the sequencing libraries, ran illumina hiseq2000 and performed sequence quality analyzes	prepared the sequencing libraries, ran illumina hiseq2000 and performed sequence quality analyzes	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5237526	28088165	GR	2	isolated and characterized bacterial isolates understudy	isolated and characterized bacterial isolates understudy	Performed the experiments	Investigation	YES
5237526	28088165	HG	2	participated in the analysis and in the writing of the manuscript	participated in the analysis and in the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5237526	28088165	IS	2	isolated and characterized bacterial isolates understudy	isolated and characterized bacterial isolates understudy	Performed the experiments	Investigation	YES
5237526	28088165	JM	2	participated in the analysis and in the writing of the manuscript	participated in the analysis and in the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5237526	28088165	MR	2	prepared the sequencing libraries, ran illumina hiseq2000 and performed sequence quality analyzes	prepared the sequencing libraries, ran illumina hiseq2000 and performed sequence quality analyzes	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5237526	28088165	NT	2	participated in the analysis and in the writing of the manuscript|performed the phenotypic macroarray assays|performed the carbohydrate fermentation assays, nodulation tests and tolerance assays|isolated and characterized bacterial isolates understudy	participated in the analysis and in the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5237526	28088165	NT	2	participated in the analysis and in the writing of the manuscript|performed the phenotypic macroarray assays|performed the carbohydrate fermentation assays, nodulation tests and tolerance assays|isolated and characterized bacterial isolates understudy	performed the phenotypic macroarray assays	Performed the experiments	Investigation	YES
5237526	28088165	NT	2	participated in the analysis and in the writing of the manuscript|performed the phenotypic macroarray assays|performed the carbohydrate fermentation assays, nodulation tests and tolerance assays|isolated and characterized bacterial isolates understudy	performed the carbohydrate fermentation assays, nodulation tests and tolerance assays	Performed the experiments	Investigation	YES
5237526	28088165	NT	2	participated in the analysis and in the writing of the manuscript|performed the phenotypic macroarray assays|performed the carbohydrate fermentation assays, nodulation tests and tolerance assays|isolated and characterized bacterial isolates understudy	isolated and characterized bacterial isolates understudy	Performed the experiments	Investigation	YES
5237526	28088165	SR	2	performed the carbohydrate fermentation assays, nodulation tests and tolerance assays	performed the carbohydrate fermentation assays, nodulation tests and tolerance assays	Performed the experiments	Investigation	YES
5237526	28088165	TM	2	performed the phenotypic macroarray assays|performed the malonate utilization assay|performed eckhardt gel analyzes	performed the phenotypic macroarray assays	Performed the experiments	Investigation	YES
5237526	28088165	TM	2	performed the phenotypic macroarray assays|performed the malonate utilization assay|performed eckhardt gel analyzes	performed the malonate utilization assay	Performed the experiments	Investigation	YES
5237526	28088165	TM	2	performed the phenotypic macroarray assays|performed the malonate utilization assay|performed eckhardt gel analyzes	performed eckhardt gel analyzes	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4583208	26417422	All other authors	2	expressed and purified enzymes	expressed and purified enzymes	Performed the experiments	Investigation	YES
4583208	26417422	B.W.	2	performed chemical synthesis and nmr analysis	performed chemical synthesis and nmr analysis	Performed the experiments	Investigation	YES
4583208	26417422	C.M.	2	designed experiments, analyzed data and wrote the manuscript|performed ms analysis	designed experiments, analyzed data and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4583208	26417422	C.M.	2	designed experiments, analyzed data and wrote the manuscript|performed ms analysis	performed ms analysis	Performed the experiments	Investigation	YES
4583208	26417422	J.Q.	2	performed ms analysis	performed ms analysis	Performed the experiments	Investigation	YES
4583208	26417422	L.L.	2	designed experiments, analyzed data and wrote the manuscript|performed enzymatic synthesis, purification and hplc identification of glycans	designed experiments, analyzed data and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4583208	26417422	L.L.	2	designed experiments, analyzed data and wrote the manuscript|performed enzymatic synthesis, purification and hplc identification of glycans	performed enzymatic synthesis, purification and hplc identification of glycans	Performed the experiments	Investigation	YES
4583208	26417422	N.W.	2	performed ms analysis	performed ms analysis	Performed the experiments	Investigation	YES
4583208	26417422	P.G.W.	2	designed experiments, analyzed data and wrote the manuscript	designed experiments, analyzed data and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4583208	26417422	Y.L.	2	designed experiments, analyzed data and wrote the manuscript|performed chemical synthesis and nmr analysis	designed experiments, analyzed data and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4583208	26417422	Y.L.	2	designed experiments, analyzed data and wrote the manuscript|performed chemical synthesis and nmr analysis	performed chemical synthesis and nmr analysis	Performed the experiments	Investigation	YES
4583208	26417422	Z.X.	2	performed chemical synthesis and nmr analysis	performed chemical synthesis and nmr analysis	Performed the experiments	Investigation	YES
5828556	29254680	All authors	2	also contributed conduct of the trial, drafting and approving the final manuscript	also contributed conduct of the trial, drafting and approving the final manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5828556	29254680	DM	2	conceived and planned the study of ethnicity as part of a larger bioequivalence trial organized by the authors	conceived and planned the study of ethnicity as part of a larger bioequivalence trial organized by the authors	Conceived and designed the experiments	Conceptualization|Project administration	YES
5828556	29254680	NH	2	led the laboratory and statistical procedures, respectively	led the laboratory and statistical procedures, respectively	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5828556	29254680	PG	2	led the laboratory and statistical procedures, respectively	led the laboratory and statistical procedures, respectively	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5597101	28975910	All authors	2	were involved in study design|contributed to questionnaire drafting and revisions|have reviewed the paper and agree to its publication	were involved in study design	Conceived and designed the experiments	Methodology	YES
5597101	28975910	All authors	2	were involved in study design|contributed to questionnaire drafting and revisions|have reviewed the paper and agree to its publication	contributed to questionnaire drafting and revisions	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5597101	28975910	All authors	2	were involved in study design|contributed to questionnaire drafting and revisions|have reviewed the paper and agree to its publication	have reviewed the paper and agree to its publication	Wrote the paper	Writing - Review & Editing	YES
5597101	28975910	Catherine Dewsbury	2	conducted the pharmacist interviews from which the questionnaire was developed, and contributed to the questionnaire distribution	conducted the pharmacist interviews from which the questionnaire was developed, and contributed to the questionnaire distribution	Performed the experiments	Investigation	YES
5597101	28975910	Janet Krska	2	conducted the analysis and wrote the first draft of the paper	conducted the analysis and wrote the first draft of the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4595457	26443752	AC	2	was critically reviewed and subsequently approved by all authors	was critically reviewed and subsequently approved by all authors	-	-	NO
4595457	26443752	SP	2	was critically reviewed and subsequently approved by all authors	was critically reviewed and subsequently approved by all authors	-	-	NO
4866531	27222711	Amit Jain	PLoS52	contributed equally in data collection and analysis	contributed equally in data collection and analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
4866531	27222711	Harsh Shah	PLoS52	contributed equally in data collection and analysis	contributed equally in data collection and analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
4866531	27222711	Nikhil Gupta	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4866531	27222711	Nilesh Sadashiv Patil	PLoS52	contributed equally in data collection and analysis	contributed equally in data collection and analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
4866531	27222711	Pramod Kumar Mishra	PLoS52	designed the study|also helped in editing the paper	designed the study	Conceived and designed the experiments	Methodology	YES
4866531	27222711	Pramod Kumar Mishra	PLoS52	designed the study|also helped in editing the paper	also helped in editing the paper	Wrote the paper	Writing - Review & Editing	YES
4866531	27222711	Sundeep Singh Saluja	PLoS52	designed the study|wrote the paper	designed the study	Conceived and designed the experiments	Methodology	YES
4866531	27222711	Sundeep Singh Saluja	PLoS52	designed the study|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4866531	27222711	Vaibhav Kumar Varshney	PLoS52	contributed equally in data collection and analysis	contributed equally in data collection and analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5267582	28124233	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5267582	28124233	BD	2	devised the study|wrote the first draft of the manuscript	devised the study	Conceived and designed the experiments	Conceptualization	YES
5267582	28124233	BD	2	devised the study|wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
5267582	28124233	FH	2	constructed the electronic database|performed the data analyses	constructed the electronic database	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5267582	28124233	FH	2	constructed the electronic database|performed the data analyses	performed the data analyses	Analyzed the data	Formal analysis	YES
5267582	28124233	LDY	2	constructed the electronic database|performed the data analyses	constructed the electronic database	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5267582	28124233	LDY	2	constructed the electronic database|performed the data analyses	performed the data analyses	Analyzed the data	Formal analysis	YES
5267582	28124233	PWW	2	assessed the patients|performed the data analyses	assessed the patients	-	-	NO
5267582	28124233	PWW	2	assessed the patients|performed the data analyses	performed the data analyses	Analyzed the data	Formal analysis	YES
5267582	28124233	SM	2	assessed the patients|performed the data analyses	assessed the patients	-	-	NO
5267582	28124233	SM	2	assessed the patients|performed the data analyses	performed the data analyses	Analyzed the data	Formal analysis	YES
5267582	28124233	SS	2	constructed the electronic database|performed the data analyses	constructed the electronic database	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5267582	28124233	SS	2	constructed the electronic database|performed the data analyses	performed the data analyses	Analyzed the data	Formal analysis	YES
5267582	28124233	TAK	2	devised the study|assessed the patients	devised the study	Conceived and designed the experiments	Conceptualization	YES
5267582	28124233	TAK	2	devised the study|assessed the patients	assessed the patients	-	-	NO
4404344	25893244	AF	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper|Initiated the study and obtained the funding	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404344	25893244	AF	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper|Initiated the study and obtained the funding	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404344	25893244	AF	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper|Initiated the study and obtained the funding	Initiated the study and obtained the funding	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
4404344	25893244	CF	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404344	25893244	CF	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404344	25893244	IP	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404344	25893244	IP	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404344	25893244	IP	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404344	25893244	MW	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Initiated the study and obtained the funding	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404344	25893244	MW	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Initiated the study and obtained the funding	Performed the experiments	Performed the experiments	Investigation	YES
4404344	25893244	MW	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Initiated the study and obtained the funding	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404344	25893244	MW	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Initiated the study and obtained the funding	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404344	25893244	MW	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Initiated the study and obtained the funding	Initiated the study and obtained the funding	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
4404344	25893244	NB	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Initiated the study and obtained the funding	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404344	25893244	NB	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Initiated the study and obtained the funding	Performed the experiments	Performed the experiments	Investigation	YES
4404344	25893244	NB	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Initiated the study and obtained the funding	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404344	25893244	NB	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Initiated the study and obtained the funding	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404344	25893244	NB	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Initiated the study and obtained the funding	Initiated the study and obtained the funding	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
5597102	28975911	Christina Jessurun	2	conceptualized the study	conceptualized the study	Conceived and designed the experiments	Conceptualization	YES
5597102	28975911	Helene Cotton	2	conceptualized the study|oversaw its execution	conceptualized the study	Conceived and designed the experiments	Conceptualization	YES
5597102	28975911	Helene Cotton	2	conceptualized the study|oversaw its execution	oversaw its execution	Performed the experiments	Investigation|Supervision	YES
5597102	28975911	Jerry Phillips	2	oversaw its execution	oversaw its execution	Performed the experiments	Investigation|Supervision	YES
5597102	28975911	Mark A. Sembower	2	conceptualized and executed the scoring and analysis of the data	conceptualized and executed the scoring and analysis of the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation	YES
5597102	28975911	Saul Shiffman	2	conceptualized the study|conceptualized and executed the scoring and analysis of the data|drafted the manuscript, and all authors contributed substantially to the final draft	conceptualized the study	Conceived and designed the experiments	Conceptualization	YES
5597102	28975911	Saul Shiffman	2	conceptualized the study|conceptualized and executed the scoring and analysis of the data|drafted the manuscript, and all authors contributed substantially to the final draft	conceptualized and executed the scoring and analysis of the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation	YES
5597102	28975911	Saul Shiffman	2	conceptualized the study|conceptualized and executed the scoring and analysis of the data|drafted the manuscript, and all authors contributed substantially to the final draft	drafted the manuscript, and all authors contributed substantially to the final draft	Wrote the paper	Writing - Original Draft	YES
5597102	28975911	Steve Pype	2	conceptualized and executed the scoring and analysis of the data	conceptualized and executed the scoring and analysis of the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation	YES
5828558	29246479	AM	PLoS52	analyzed the data|wrote the paper and all authors were involved in editing the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5828558	29246479	AM	PLoS52	analyzed the data|wrote the paper and all authors were involved in editing the paper	wrote the paper and all authors were involved in editing the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5828558	29246479	AN	PLoS52	generated data related to the effect of 3-hib on different cell types	generated data related to the effect of 3-hib on different cell types	Performed the experiments	Investigation	YES
5828558	29246479	AS	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5828558	29246479	CL	PLoS52	were involved in the generation of metabolomics data	were involved in the generation of metabolomics data	-	Investigation	YES
5828558	29246479	EF	PLoS52	were involved in the generation of metabolomics data	were involved in the generation of metabolomics data	-	Investigation	YES
5828558	29246479	JB	PLoS52	were involved in the generation of metabolomics data	were involved in the generation of metabolomics data	-	Investigation	YES
5828558	29246479	LAL	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5828558	29246479	MB	PLoS52	were involved in the generation of metabolomics data	were involved in the generation of metabolomics data	-	Investigation	YES
5828558	29246479	ML	PLoS52	were involved in the generation of metabolomics data	were involved in the generation of metabolomics data	-	Investigation	YES
5828558	29246479	NJW	PLoS52	were involved in the generation of metabolomics data	were involved in the generation of metabolomics data	-	Investigation	YES
5828558	29246479	SG	PLoS52	generated data related to the effect of 3-hib on different cell types	generated data related to the effect of 3-hib on different cell types	Performed the experiments	Investigation	YES
5828558	29246479	US	PLoS52	were involved in the generation of metabolomics data|generated data related to the effect of 3-hib on different cell types|wrote the paper and all authors were involved in editing the paper	were involved in the generation of metabolomics data	-	Investigation	YES
5828558	29246479	US	PLoS52	were involved in the generation of metabolomics data|generated data related to the effect of 3-hib on different cell types|wrote the paper and all authors were involved in editing the paper	generated data related to the effect of 3-hib on different cell types	Performed the experiments	Investigation	YES
5828558	29246479	US	PLoS52	were involved in the generation of metabolomics data|generated data related to the effect of 3-hib on different cell types|wrote the paper and all authors were involved in editing the paper	wrote the paper and all authors were involved in editing the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4878458	27257479	CB	7	Christine Booth: Study design, study execution, data collation	Christine Booth: Study design, study execution, data collation	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4878458	27257479	CZ	7	Craig Zimitat: Study design, study execution	Craig Zimitat: Study design, study execution	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4878458	27257479	DM	7	Danni Maguire: Software design, software programming	Danni Maguire: Software design, software programming	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
4878458	27257479	JA	7	Joyce Abraham: Analysis of IT information (Software life cycle, Software quality assurance analysis	Joyce Abraham: Analysis of IT information (Software life cycle, Software quality assurance analysis	Performed the experiments|Contributed reagents/materials/analysis tools	Software|Validation	YES
4878458	27257479	RC	7	Rajkumar Cheluvappa: Data collation, data analysis, manuscript drafting, manuscript editing, manuscript submission, de facto correspondences	Rajkumar Cheluvappa: Data collation, data analysis, manuscript drafting, manuscript editing, manuscript submission, de facto correspondences	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
4878458	27257479	RE	7	Rajaraman Eri: Study design, study execution, de jure	Rajaraman Eri: Study design, study execution, de jure	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4878458	27257479	ZB	7	Zack Bellinson: Software design, software programming	Zack Bellinson: Software design, software programming	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
5517397	28775732	AP	2	contributed to the design and conception of the work together to the drafting of the manuscript	contributed to the design and conception of the work together to the drafting of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5517397	28775732	GN	2	contributed to the interpretation of the generated data and to the revision of the manuscript	contributed to the interpretation of the generated data and to the revision of the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Review & Editing	YES
5517397	28775732	LM	2	contributed to the interpretation of the generated data and to the revision of the manuscript	contributed to the interpretation of the generated data and to the revision of the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Review & Editing	YES
5517397	28775732	MP	2	contributed to the interpretation of the generated data and to the revision of the manuscript	contributed to the interpretation of the generated data and to the revision of the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Review & Editing	YES
5517397	28775732	SC	2	contributed to the design and conception of the work together to the drafting of the manuscript	contributed to the design and conception of the work together to the drafting of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4598331	26449273	JSGM	CRediT	Obtained funding|supervision	Obtained funding	-	Funding acquisition	YES
4598331	26449273	JSGM	CRediT	Obtained funding|supervision	supervision	-	Supervision	YES
4598331	26449273	RSH	CRediT	supervision	supervision	-	Supervision	YES
4598331	26449273	VDL	CRediT	Study concept and design|Obtained funding	Study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4598331	26449273	VDL	CRediT	Study concept and design|Obtained funding	Obtained funding	-	Funding acquisition	YES
5356267	28302125	Abiy Yigzaw	2	is also highly acknowledged for final edition of the manuscript related to language usage, spelling and grammar	is also highly acknowledged for final edition of the manuscript related to language usage, spelling and grammar	Wrote the paper	Writing - Review & Editing	YES
5356267	28302125	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5356267	28302125	Felege-Hiwot Teaching	2	specialized hospital	specialized hospital	-	-	NO
5356267	28302125	Ph.D.	2	student with close supervision of the two professors	student with close supervision of the two professors	-	Supervision	YES
5356267	28302125	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5289931	28155204	All authors	2	reviewed, revised and approved the final manuscript	reviewed, revised and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5289931	28155204	Daniel Brett	2	who was formerly employed as a junior research assistant in newcastle and helped to undertake some of the early literature searches for a previous in-house review on a similar, related topic	who was formerly employed as a junior research assistant in newcastle and helped to undertake some of the early literature searches for a previous in-house review on a similar, related topic	-	Formal analysis	YES
5289931	28155204	FR	2	undertook literature searches and submitted an earlier version of this systematic review as her doctoral dissertation	undertook literature searches and submitted an earlier version of this systematic review as her doctoral dissertation	Performed the experiments	Formal analysis|Investigation	YES
5289931	28155204	FSF	2	funding for a study of youth with emerging mood, alcohol and substance use disorders	funding for a study of youth with emerging mood, alcohol and substance use disorders	-	Funding acquisition	YES
5289931	28155204	JS	2	revised the dissertation manuscript to produce the first draft of the study	revised the dissertation manuscript to produce the first draft of the study	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5289931	28155204	TM	2	further refined the outline and developed the search terms	further refined the outline and developed the search terms	-	-	NO
4404345	25893250	CMZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404345	25893250	CMZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404345	25893250	CMZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404345	25893250	CMZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404345	25893250	CMZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404345	25893250	FY	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4404345	25893250	JW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4404345	25893250	LL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Funding	Performed the experiments	Performed the experiments	Investigation	YES
4404345	25893250	LL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Funding	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404345	25893250	LL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Funding	Funding	-	Funding acquisition	YES
4404345	25893250	LYP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Funding	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404345	25893250	LYP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Funding	Analyzed the data	Analyzed the data	Formal analysis	YES
4404345	25893250	LYP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Funding	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404345	25893250	LYP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Funding	Funding	-	Funding acquisition	YES
4404345	25893250	RGL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4404345	25893250	XBQ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4404345	25893250	XLZ	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4404345	25893250	XLZ	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404345	25893250	XYL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4404345	25893250	XYL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404345	25893250	YQY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Funding	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404345	25893250	YQY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Funding	Performed the experiments	Performed the experiments	Investigation	YES
4404345	25893250	YQY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Funding	Analyzed the data	Analyzed the data	Formal analysis	YES
4404345	25893250	YQY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Funding	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404345	25893250	YQY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Funding	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404345	25893250	YQY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Funding	Funding	-	Funding acquisition	YES
5240218	28095778	AF	2	assisted in drawing the conclusions and preparing the manuscript	assisted in drawing the conclusions and preparing the manuscript	Wrote the paper	Writing - Original Draft	YES
5240218	28095778	ALG	2	assisted in drawing the conclusions and preparing the manuscript	assisted in drawing the conclusions and preparing the manuscript	Wrote the paper	Writing - Original Draft	YES
5240218	28095778	DdP	2	assisted in drawing the conclusions and preparing the manuscript	assisted in drawing the conclusions and preparing the manuscript	Wrote the paper	Writing - Original Draft	YES
5240218	28095778	EB	2	conceived the work|carried out the analyses|prepared the manuscript	conceived the work	Conceived and designed the experiments	Conceptualization	YES
5240218	28095778	EB	2	conceived the work|carried out the analyses|prepared the manuscript	carried out the analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5240218	28095778	EB	2	conceived the work|carried out the analyses|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5240218	28095778	EP	2	assisted in drawing the conclusions and preparing the manuscript|assisted in drawing the conclusions and preparing the manuscript	assisted in drawing the conclusions and preparing the manuscript	Wrote the paper	Writing - Original Draft	YES
5240218	28095778	EP	2	assisted in drawing the conclusions and preparing the manuscript|assisted in drawing the conclusions and preparing the manuscript	assisted in drawing the conclusions and preparing the manuscript	Wrote the paper	Writing - Original Draft	YES
5240218	28095778	IM	2	assisted in drawing the conclusions and preparing the manuscript	assisted in drawing the conclusions and preparing the manuscript	Wrote the paper	Writing - Original Draft	YES
5240218	28095778	MF	2	conceived the work|assisted in drawing the conclusions and preparing the manuscript	conceived the work	Conceived and designed the experiments	Conceptualization	YES
5240218	28095778	MF	2	conceived the work|assisted in drawing the conclusions and preparing the manuscript	assisted in drawing the conclusions and preparing the manuscript	Wrote the paper	Writing - Original Draft	YES
5240218	28095778	MLT	2	assisted in drawing the conclusions and preparing the manuscript	assisted in drawing the conclusions and preparing the manuscript	Wrote the paper	Writing - Original Draft	YES
5240218	28095778	RF	2	conceived the work|assisted in drawing the conclusions and preparing the manuscript	conceived the work	Conceived and designed the experiments	Conceptualization	YES
5240218	28095778	RF	2	conceived the work|assisted in drawing the conclusions and preparing the manuscript	assisted in drawing the conclusions and preparing the manuscript	Wrote the paper	Writing - Original Draft	YES
5240218	28095778	VO	2	assisted in drawing the conclusions and preparing the manuscript	assisted in drawing the conclusions and preparing the manuscript	Wrote the paper	Writing - Original Draft	YES
4878566	27257484	EI	2	have get in on a discussion about this study	have get in on a discussion about this study	-	-	NO
4878566	27257484	KN	2	have get in on a discussion about this study	have get in on a discussion about this study	-	-	NO
4878566	27257484	MK	2	have get in on a discussion about this study	have get in on a discussion about this study	-	-	NO
4878566	27257484	MY	2	have been involved in drafting the manuscript or revising it critically for important intellectual content	have been involved in drafting the manuscript or revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4878566	27257484	NS	2	have get in on a discussion about this study	have get in on a discussion about this study	-	-	NO
4878566	27257484	NT	2	have get in on a discussion about this study	have get in on a discussion about this study	-	-	NO
4878566	27257484	OH	2	have get in on a discussion about this study	have get in on a discussion about this study	-	-	NO
4878566	27257484	SR	2	have made substantial contributions to conception and design, or acquisition of data, or analysis and interpretation of data	have made substantial contributions to conception and design, or acquisition of data, or analysis and interpretation of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
4878566	27257484	SY	2	have get in on a discussion about this study	have get in on a discussion about this study	-	-	NO
4878566	27257484	YS	2	have given final approval of the version to be published	have given final approval of the version to be published	-	-	NO
5832612	29137891	AFC	PLoS5	Contributed to data collection and clinical evaluation|Contributed to study design	Contributed to data collection and clinical evaluation	Performed the experiments	Investigation	YES
5832612	29137891	AFC	PLoS5	Contributed to data collection and clinical evaluation|Contributed to study design	Contributed to study design	Conceived and designed the experiments	Methodology	YES
5832612	29137891	APG	PLoS5	Contributed to study design|Contributed to data analysis|Wrote the paper	Contributed to study design	Conceived and designed the experiments	Methodology	YES
5832612	29137891	APG	PLoS5	Contributed to study design|Contributed to data analysis|Wrote the paper	Contributed to data analysis	Analyzed the data	Formal analysis	YES
5832612	29137891	APG	PLoS5	Contributed to study design|Contributed to data analysis|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5832612	29137891	All	PLoS5	Contributed to editing the paper	Contributed to editing the paper	Wrote the paper	Writing - Review & Editing	YES
5832612	29137891	BEE	PLoS5	Contributed to data collection and clinical evaluation|Contributed to study design	Contributed to data collection and clinical evaluation	Performed the experiments	Investigation	YES
5832612	29137891	BEE	PLoS5	Contributed to data collection and clinical evaluation|Contributed to study design	Contributed to study design	Conceived and designed the experiments	Methodology	YES
5832612	29137891	LMJ	PLoS5	Contributed to data collection and clinical evaluation|Contributed to study design|Contributed to data analysis|Wrote the paper	Contributed to data collection and clinical evaluation	Performed the experiments	Investigation	YES
5832612	29137891	LMJ	PLoS5	Contributed to data collection and clinical evaluation|Contributed to study design|Contributed to data analysis|Wrote the paper	Contributed to study design	Conceived and designed the experiments	Methodology	YES
5832612	29137891	LMJ	PLoS5	Contributed to data collection and clinical evaluation|Contributed to study design|Contributed to data analysis|Wrote the paper	Contributed to data analysis	Analyzed the data	Formal analysis	YES
5832612	29137891	LMJ	PLoS5	Contributed to data collection and clinical evaluation|Contributed to study design|Contributed to data analysis|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5832612	29137891	PC	PLoS5	Contributed to data collection and clinical evaluation|Contributed to study design|Contributed to data analysis	Contributed to data collection and clinical evaluation	Performed the experiments	Investigation	YES
5832612	29137891	PC	PLoS5	Contributed to data collection and clinical evaluation|Contributed to study design|Contributed to data analysis	Contributed to study design	Conceived and designed the experiments	Methodology	YES
5832612	29137891	PC	PLoS5	Contributed to data collection and clinical evaluation|Contributed to study design|Contributed to data analysis	Contributed to data analysis	Analyzed the data	Formal analysis	YES
5832612	29137891	SML	PLoS5	Contributed to data collection and clinical evaluation|Contributed to study design	Contributed to data collection and clinical evaluation	Performed the experiments	Investigation	YES
5832612	29137891	SML	PLoS5	Contributed to data collection and clinical evaluation|Contributed to study design	Contributed to study design	Conceived and designed the experiments	Methodology	YES
5517400	28775730	JA	2	designed the experiment|drafted the paper	designed the experiment	Conceived and designed the experiments	Methodology	YES
5517400	28775730	JA	2	designed the experiment|drafted the paper	drafted the paper	Wrote the paper	Writing - Original Draft	YES
5517400	28775730	JX	2	designed the experiment	designed the experiment	Conceived and designed the experiments	Methodology	YES
5517400	28775730	KC	2	drafted the paper	drafted the paper	Wrote the paper	Writing - Original Draft	YES
5517400	28775730	WW	2	performed the analysis and interpretation of the data	performed the analysis and interpretation of the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5517400	28775730	XW	2	performed the phenotypic collection|performed the analysis and interpretation of the data	performed the phenotypic collection	Performed the experiments	Investigation	YES
5517400	28775730	XW	2	performed the phenotypic collection|performed the analysis and interpretation of the data	performed the analysis and interpretation of the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5517400	28775730	YP	2	performed the phenotypic collection|performed the analysis and interpretation of the data|drafted the paper	performed the phenotypic collection	Performed the experiments	Investigation	YES
5517400	28775730	YP	2	performed the phenotypic collection|performed the analysis and interpretation of the data|drafted the paper	performed the analysis and interpretation of the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5517400	28775730	YP	2	performed the phenotypic collection|performed the analysis and interpretation of the data|drafted the paper	drafted the paper	Wrote the paper	Writing - Original Draft	YES
5517400	28775730	ZKL	2	designed the experiment|drafted the paper	designed the experiment	Conceived and designed the experiments	Methodology	YES
5517400	28775730	ZKL	2	designed the experiment|drafted the paper	drafted the paper	Wrote the paper	Writing - Original Draft	YES
5517400	28775730	all authors	2	revised the paper and approved the final version to be published	revised the paper and approved the final version to be published	Wrote the paper	Writing - Review & Editing	YES
5597103	28975912	Derek Stewart	4	which was then revised by	which was then revised by	Wrote the paper	Writing - Review & Editing	YES
5359813	28331527	ART	2	nurses and data managers	nurses and data managers	Analyzed the data	Data curation|Project administration	YES
5359813	28331527	All	2	data underlying the findings are fully available online without restriction	data underlying the findings are fully available online without restriction	-	-	NO
5359813	28331527	All authors	2	read and approved the final manuscript|shared professional contribution for this study	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5359813	28331527	All authors	2	read and approved the final manuscript|shared professional contribution for this study	shared professional contribution for this study	-	-	NO
5359813	28331527	BBG	2	equally participated in this study|participated from objective formulation to manuscript drafting	equally participated in this study	-	-	NO
5359813	28331527	BBG	2	equally participated in this study|participated from objective formulation to manuscript drafting	participated from objective formulation to manuscript drafting	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5359813	28331527	DT	2	equally participated in this study|are participated during data analysis and manuscript drafting	equally participated in this study	-	-	NO
5359813	28331527	DT	2	equally participated in this study|are participated during data analysis and manuscript drafting	are participated during data analysis and manuscript drafting	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5359813	28331527	Health Center	2	staff, study participants, data collectors and supervisors deserve acknowledgement for their unreserved support	staff, study participants, data collectors and supervisors deserve acknowledgement for their unreserved support	Performed the experiments	Investigation|Supervision	YES
5359813	28331527	MA	2	equally participated in this study|are participated during data analysis and manuscript drafting	equally participated in this study	-	-	NO
5359813	28331527	MA	2	equally participated in this study|are participated during data analysis and manuscript drafting	are participated during data analysis and manuscript drafting	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5359813	28331527	MK	2	are participated during data analysis and manuscript drafting	are participated during data analysis and manuscript drafting	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5359813	28331527	MKY	2	equally participated in this study	equally participated in this study	-	-	NO
5359813	28331527	YAG	2	equally participated in this study|participated from objective formulation to manuscript drafting	equally participated in this study	-	-	NO
5359813	28331527	YAG	2	equally participated in this study|participated from objective formulation to manuscript drafting	participated from objective formulation to manuscript drafting	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5359813	28331527	YK	2	equally participated in this study|participated from objective formulation to manuscript drafting	equally participated in this study	-	-	NO
5359813	28331527	YK	2	equally participated in this study|participated from objective formulation to manuscript drafting	participated from objective formulation to manuscript drafting	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4604210	26462714	AB	2	contributed to the analysis and interpretation of data, and made important intellectual contributions to drafting or revising of the manuscript	contributed to the analysis and interpretation of data, and made important intellectual contributions to drafting or revising of the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft|Writing - Review & Editing	YES
4604210	26462714	CF	2	contributed to the analysis and interpretation of data, and made important intellectual contributions to drafting or revising of the manuscript	contributed to the analysis and interpretation of data, and made important intellectual contributions to drafting or revising of the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft|Writing - Review & Editing	YES
4604210	26462714	DW	2	contributed to the analysis and interpretation of data, and made important intellectual contributions to drafting or revising of the manuscript	contributed to the analysis and interpretation of data, and made important intellectual contributions to drafting or revising of the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft|Writing - Review & Editing	YES
4604210	26462714	FT	2	contributed to the analysis and interpretation of data, and made important intellectual contributions to drafting or revising of the manuscript	contributed to the analysis and interpretation of data, and made important intellectual contributions to drafting or revising of the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft|Writing - Review & Editing	YES
4604210	26462714	FV	2	conceived the research idea, designed the study, conducted the analysis and lead the writing of the manuscript	conceived the research idea, designed the study, conducted the analysis and lead the writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Writing - Original Draft	YES
4604210	26462714	HB	2	contributed to the analysis and interpretation of data, and made important intellectual contributions to drafting or revising of the manuscript	contributed to the analysis and interpretation of data, and made important intellectual contributions to drafting or revising of the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft|Writing - Review & Editing	YES
4604210	26462714	LN	2	contributed to the analysis and interpretation of data, and made important intellectual contributions to drafting or revising of the manuscript	contributed to the analysis and interpretation of data, and made important intellectual contributions to drafting or revising of the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft|Writing - Review & Editing	YES
4604210	26462714	WM	2	contributed to the analysis and interpretation of data, and made important intellectual contributions to drafting or revising of the manuscript	contributed to the analysis and interpretation of data, and made important intellectual contributions to drafting or revising of the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft|Writing - Review & Editing	YES
4404346	25894396	BCA	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4404346	25894396	BCA	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4404346	25894396	HKS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404346	25894396	JNG	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404346	25894396	MAF	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404346	25894396	OD	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404346	25894396	OD	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404346	25894396	SW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404346	25894396	SW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404346	25894396	SW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404346	25894396	TH	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404346	25894396	TH	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5517402	28785273	GC	2	assisted with discussing of the results|helped to revise the manuscript	assisted with discussing of the results	-	-	NO
5517402	28785273	GC	2	assisted with discussing of the results|helped to revise the manuscript	helped to revise the manuscript	Wrote the paper	Writing - Review & Editing	YES
5517402	28785273	LZ	2	assisted with discussing of the results	assisted with discussing of the results	-	-	NO
5517402	28785273	TL	2	conceived and designed the study|performed the experiments, analyzed the data, and wrote the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5517402	28785273	TL	2	conceived and designed the study|performed the experiments, analyzed the data, and wrote the manuscript	performed the experiments, analyzed the data, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5517402	28785273	TS	2	helped to revise the manuscript	helped to revise the manuscript	Wrote the paper	Writing - Review & Editing	YES
4607700	26471265	DG	2	conducted the screening, data extraction and analysis|prepared the first draft of the manuscript|reviewed and commented on all subsequent drafts of the manuscript including the final draft	conducted the screening, data extraction and analysis	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
4607700	26471265	DG	2	conducted the screening, data extraction and analysis|prepared the first draft of the manuscript|reviewed and commented on all subsequent drafts of the manuscript including the final draft	prepared the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
4607700	26471265	DG	2	conducted the screening, data extraction and analysis|prepared the first draft of the manuscript|reviewed and commented on all subsequent drafts of the manuscript including the final draft	reviewed and commented on all subsequent drafts of the manuscript including the final draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4607700	26471265	HA-H	2	reviewed and commented on all subsequent drafts of the manuscript including the final draft	reviewed and commented on all subsequent drafts of the manuscript including the final draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4607700	26471265	KK	2	conceptualized the review, conducted the search and drafted the proposal|conducted the screening, data extraction and analysis|prepared the first draft of the manuscript|reviewed and commented on all subsequent drafts of the manuscript including the final draft	conceptualized the review, conducted the search and drafted the proposal	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
4607700	26471265	KK	2	conceptualized the review, conducted the search and drafted the proposal|conducted the screening, data extraction and analysis|prepared the first draft of the manuscript|reviewed and commented on all subsequent drafts of the manuscript including the final draft	conducted the screening, data extraction and analysis	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
4607700	26471265	KK	2	conceptualized the review, conducted the search and drafted the proposal|conducted the screening, data extraction and analysis|prepared the first draft of the manuscript|reviewed and commented on all subsequent drafts of the manuscript including the final draft	prepared the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
4607700	26471265	KK	2	conceptualized the review, conducted the search and drafted the proposal|conducted the screening, data extraction and analysis|prepared the first draft of the manuscript|reviewed and commented on all subsequent drafts of the manuscript including the final draft	reviewed and commented on all subsequent drafts of the manuscript including the final draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4607700	26471265	NF	2	reviewed and commented on all subsequent drafts of the manuscript including the final draft	reviewed and commented on all subsequent drafts of the manuscript including the final draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4607700	26471265	RAF	2	prepared the first draft of the manuscript|reviewed and commented on all subsequent drafts of the manuscript including the final draft	prepared the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
4607700	26471265	RAF	2	prepared the first draft of the manuscript|reviewed and commented on all subsequent drafts of the manuscript including the final draft	reviewed and commented on all subsequent drafts of the manuscript including the final draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4607700	26471265	SA	2	reviewed and commented on all subsequent drafts of the manuscript including the final draft	reviewed and commented on all subsequent drafts of the manuscript including the final draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4607700	26471265	SMSW	2	reviewed and commented on all subsequent drafts of the manuscript including the final draft	reviewed and commented on all subsequent drafts of the manuscript including the final draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4475539	26137493	Angela Falco	2	acquired and analyzed the data	acquired and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4475539	26137493	Bruno Lorusso	2	designed the study and wrote the paper	designed the study and wrote the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4475539	26137493	Caterina Frati	2	acquired and analyzed the data	acquired and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4475539	26137493	Costanza Lagrasta	2	critically revised the paper prior to submission	critically revised the paper prior to submission	Wrote the paper	Writing - Review & Editing	YES
4475539	26137493	Davide Maselli	2	acquired and analyzed the data	acquired and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4475539	26137493	Denise Madeddu	2	acquired and analyzed the data	acquired and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4475539	26137493	Enrico M. Silini	2	are responsible for morphologic and histopathologic analysis	are responsible for morphologic and histopathologic analysis	Performed the experiments	Investigation	YES
4475539	26137493	Eugenio Quaini	2	are responsible for selection and enrollment of patients and surgical procedures	are responsible for selection and enrollment of patients and surgical procedures	Performed the experiments	Investigation	YES
4475539	26137493	Federico Quaini	2	designed the study and wrote the paper	designed the study and wrote the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4475539	26137493	Gallia Graiani	2	acquired and analyzed the data	acquired and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4475539	26137493	Laura Rinaldi	2	acquired and analyzed the data	acquired and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4475539	26137493	Letizia Gnetti	2	are responsible for morphologic and histopathologic analysis	are responsible for morphologic and histopathologic analysis	Performed the experiments	Investigation	YES
4475539	26137493	Luca Ampollini	2	are responsible for selection and enrollment of patients and surgical procedures	are responsible for selection and enrollment of patients and surgical procedures	Performed the experiments	Investigation	YES
4475539	26137493	Paolo Carbognani	2	are responsible for selection and enrollment of patients and surgical procedures	are responsible for selection and enrollment of patients and surgical procedures	Performed the experiments	Investigation	YES
4475539	26137493	Stefano Cavalli	2	critically revised the paper prior to submission	critically revised the paper prior to submission	Wrote the paper	Writing - Review & Editing	YES
5240378	28095770	ALR	PLoS52	analyzed the data|prepared the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5240378	28095770	ALR	PLoS52	analyzed the data|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5240378	28095770	AW	PLoS52	analyzed the data|provided bioinformatics support|collected and provided samples|prepared the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5240378	28095770	AW	PLoS52	analyzed the data|provided bioinformatics support|collected and provided samples|prepared the manuscript	provided bioinformatics support	-	Formal analysis	YES
5240378	28095770	AW	PLoS52	analyzed the data|provided bioinformatics support|collected and provided samples|prepared the manuscript	collected and provided samples	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5240378	28095770	AW	PLoS52	analyzed the data|provided bioinformatics support|collected and provided samples|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5240378	28095770	CS	PLoS52	analyzed the data|provided bioinformatics support|prepared the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5240378	28095770	CS	PLoS52	analyzed the data|provided bioinformatics support|prepared the manuscript	provided bioinformatics support	-	Formal analysis	YES
5240378	28095770	CS	PLoS52	analyzed the data|provided bioinformatics support|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5240378	28095770	WM	PLoS52	conceived the study|analyzed the data|collected and provided samples|prepared the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5240378	28095770	WM	PLoS52	conceived the study|analyzed the data|collected and provided samples|prepared the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5240378	28095770	WM	PLoS52	conceived the study|analyzed the data|collected and provided samples|prepared the manuscript	collected and provided samples	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5240378	28095770	WM	PLoS52	conceived the study|analyzed the data|collected and provided samples|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5293713	28155206	All authors	2	were involved in the draft manuscript and initial review	were involved in the draft manuscript and initial review	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5359922	28331526	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5359922	28331526	BR	2	contributed to the overall analysis of the data	contributed to the overall analysis of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5359922	28331526	DS	2	performed all cell culture, molecular, and sequencing experiments	performed all cell culture, molecular, and sequencing experiments	Performed the experiments	Investigation	YES
5359922	28331526	JH	2	performed all cell culture, molecular, and sequencing experiments	performed all cell culture, molecular, and sequencing experiments	Performed the experiments	Investigation	YES
5359922	28331526	JW	2	designed the study, collected and assembled the data, wrote and drafted the manuscript|performed all cell culture, molecular, and sequencing experiments|contributed to the overall analysis of the data	designed the study, collected and assembled the data, wrote and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5359922	28331526	JW	2	designed the study, collected and assembled the data, wrote and drafted the manuscript|performed all cell culture, molecular, and sequencing experiments|contributed to the overall analysis of the data	performed all cell culture, molecular, and sequencing experiments	Performed the experiments	Investigation	YES
5359922	28331526	JW	2	designed the study, collected and assembled the data, wrote and drafted the manuscript|performed all cell culture, molecular, and sequencing experiments|contributed to the overall analysis of the data	contributed to the overall analysis of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5359922	28331526	LS	2	performed all cell culture, molecular, and sequencing experiments	performed all cell culture, molecular, and sequencing experiments	Performed the experiments	Investigation	YES
5359922	28331526	MEQM	2	designed the study, collected and assembled the data, wrote and drafted the manuscript|contributed to the overall analysis of the data	designed the study, collected and assembled the data, wrote and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5359922	28331526	MEQM	2	designed the study, collected and assembled the data, wrote and drafted the manuscript|contributed to the overall analysis of the data	contributed to the overall analysis of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5359922	28331526	MML	2	contributed to the overall analysis of the data	contributed to the overall analysis of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5359922	28331526	MP	2	performed all cell culture, molecular, and sequencing experiments	performed all cell culture, molecular, and sequencing experiments	Performed the experiments	Investigation	YES
5359922	28331526	RMG	2	performed all cell culture, molecular, and sequencing experiments	performed all cell culture, molecular, and sequencing experiments	Performed the experiments	Investigation	YES
4878844	27257482	AA	7	data collection, manuscript editing, manuscript review	data collection, manuscript editing, manuscript review	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4878844	27257482	AB	7	data collection, data analysis, statistical analysis, interpretation of data	data collection, data analysis, statistical analysis, interpretation of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4878844	27257482	IJ	7	data collection, literature search, manuscript editing	data collection, literature search, manuscript editing	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
4878844	27257482	MFT	7	data collection, data analysis, statistical analysis	data collection, data analysis, statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4878844	27257482	NJ	7	guarantor of this research work, concept, design, literature search, manuscript preparation	guarantor of this research work, concept, design, literature search, manuscript preparation	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
4878844	27257482	UDM	7	data collection, data analysis, statistical analysis	data collection, data analysis, statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5517405	28775733	HD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5517405	28775733	HD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
5517405	28775733	HD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5517405	28775733	HD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5517405	28775733	HR	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5517405	28775733	NA	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5517405	28775733	T-XL	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5517405	28775733	T-XL	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5517405	28775733	Y-HL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5517405	28775733	Z-FZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5835543	29339100	ACE	2	was responsible for the intervention studies and analysed the aha data	was responsible for the intervention studies and analysed the aha data	Analyzed the data	Formal analysis	YES
5835543	29339100	HF	2	conceived, designed and organized the study|wrote the first manuscript draft and all authors contributed to the subsequent drafts and approved the final version	conceived, designed and organized the study	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
5835543	29339100	HF	2	conceived, designed and organized the study|wrote the first manuscript draft and all authors contributed to the subsequent drafts and approved the final version	wrote the first manuscript draft and all authors contributed to the subsequent drafts and approved the final version	Wrote the paper	Writing - Original Draft	YES
5835543	29339100	RA	2	performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
5835543	29339100	RDH	2	conceived, designed and organized the study|performed the genetic analysis	conceived, designed and organized the study	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
5835543	29339100	RDH	2	conceived, designed and organized the study|performed the genetic analysis	performed the genetic analysis	Performed the experiments	Investigation	YES
4404347	25894527	AH	PLoS5	Performed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4404347	25894527	AH	PLoS5	Performed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4404347	25894527	AJ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4404347	25894527	APF	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4404347	25894527	APF	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404347	25894527	AS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4404347	25894527	AS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404347	25894527	BW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404347	25894527	BW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404347	25894527	BW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404347	25894527	CY	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4404347	25894527	DBF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404347	25894527	DBF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404347	25894527	DBF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404347	25894527	DBF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404347	25894527	FC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4404347	25894527	FC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404347	25894527	HM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4404347	25894527	JPB	PLoS5	Supervised experiments	Supervised experiments	-	Supervision	YES
4404347	25894527	JVE	PLoS5	Supervised experiments	Supervised experiments	-	Supervision	YES
4404347	25894527	KRB	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404347	25894527	PM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4404347	25894527	PZ	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404347	25894527	RA	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404347	25894527	RLG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4404347	25894527	RS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4404347	25894527	TB	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4404347	25894527	TB	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404347	25894527	UO	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5307423	28155203	AHY	2	contributed to design of the study and drafted the manuscript|has been commissioned to provide lectures and advice to all major pharmaceutical companies with drugs used in affective and related disorders	contributed to design of the study and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5307423	28155203	AHY	2	contributed to design of the study and drafted the manuscript|has been commissioned to provide lectures and advice to all major pharmaceutical companies with drugs used in affective and related disorders	has been commissioned to provide lectures and advice to all major pharmaceutical companies with drugs used in affective and related disorders	-	-	NO
5307423	28155203	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5307423	28155203	FN	2	contributed to design of the study and drafted the manuscript	contributed to design of the study and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5307423	28155203	IBC	2	conceived the idea for the study, contributed to design and coordination of the study and is involved with training and	conceived the idea for the study, contributed to design and coordination of the study and is involved with training and	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
5307423	28155203	JH	2	contributed to statistical analysis and drafted the manuscript	contributed to statistical analysis and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5307423	28155203	MIH	2	contributed to design of the study, was involved in training and supervision of ras and drafted the manuscript	contributed to design of the study, was involved in training and supervision of ras and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Original Draft	YES
5307423	28155203	MMH	2	contributed to the design of the study, recruitment of participants and are doing assessments	contributed to the design of the study, recruitment of participants and are doing assessments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5307423	28155203	NH	2	conceived the idea for the study, contributed to design and coordination of the study, was involved in training and supervision of ras, and drafted the manuscript	conceived the idea for the study, contributed to design and coordination of the study, was involved in training and supervision of ras, and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Supervision|Writing - Original Draft	YES
5307423	28155203	PMH	2	contributed to design of the study and drafted the manuscript	contributed to design of the study and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5307423	28155203	RAs	2	supervised the contributed to design and coordination of the study and is involved with training and	supervised the contributed to design and coordination of the study and is involved with training and	Conceived and designed the experiments	Methodology|Project administration|Supervision	YES
5307423	28155203	RR	2	contributed to the design of the study, recruitment of participants and are doing assessments	contributed to the design of the study, recruitment of participants and are doing assessments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5360055	28320431	AN	2	participated in the interpretation of data and in the drafting and revising of the article	participated in the interpretation of data and in the drafting and revising of the article	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5360055	28320431	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5360055	28320431	KH	2	conceived of the research study	conceived of the research study	Conceived and designed the experiments	Conceptualization	YES
5360055	28320431	LA	2	contributed to the analysis and interpretation of data and the writing and revising of this article	contributed to the analysis and interpretation of data and the writing and revising of this article	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft|Writing - Review & Editing	YES
4475546	26137483	Zhe Zhao	2	have contributed equally to this work	have contributed equally to this work	-	-	NO
4609649	26477992	BMR	2	contributed to the study design and reviewed the manuscript	contributed to the study design and reviewed the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
4609649	26477992	CHW	2	conceived the study, supervised the analyses and reviewed the manuscript	conceived the study, supervised the analyses and reviewed the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Supervision|Writing - Review & Editing	YES
4609649	26477992	HLM	2	contributed to the study design and reviewed the manuscript	contributed to the study design and reviewed the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
4609649	26477992	JFB	2	contributed to the study design and reviewed the manuscript	contributed to the study design and reviewed the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
4609649	26477992	LH	2	conceived the study, supervised the analyses and reviewed the manuscript	conceived the study, supervised the analyses and reviewed the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Supervision|Writing - Review & Editing	YES
4609649	26477992	MS-L	2	contributed to the study design and reviewed the manuscript	contributed to the study design and reviewed the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
4609649	26477992	PB	2	contributed to the study design and reviewed the manuscript	contributed to the study design and reviewed the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
4609649	26477992	SI	2	conceived the study, assisted with the analyses and reviewed the manuscript	conceived the study, assisted with the analyses and reviewed the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Review & Editing	YES
4609649	26477992	SM	2	conceived the study, supervised the analyses and reviewed the manuscript	conceived the study, supervised the analyses and reviewed the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Supervision|Writing - Review & Editing	YES
4609649	26477992	TSB	2	conceived the study, conducted the analyses and drafted the manuscript	conceived the study, conducted the analyses and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
4878847	27257480	All authors	2	participated in data collection, analysis, writing and editing of the manuscript	participated in data collection, analysis, writing and editing of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5240399	28095783	All of the authors	PLoS52	contributed to the manuscript discussion	contributed to the manuscript discussion	-	-	NO
5240399	28095783	ED	PLoS52	wrote the paper|analyzed the data	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5240399	28095783	ED	PLoS52	wrote the paper|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5240399	28095783	JHC	PLoS52	designed the research and obtained funding for this research|wrote the paper|analyzed the data|had primary responsibility for the final content	designed the research and obtained funding for this research	Conceived and designed the experiments	Funding acquisition|Methodology	YES
5240399	28095783	JHC	PLoS52	designed the research and obtained funding for this research|wrote the paper|analyzed the data|had primary responsibility for the final content	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5240399	28095783	JHC	PLoS52	designed the research and obtained funding for this research|wrote the paper|analyzed the data|had primary responsibility for the final content	analyzed the data	Analyzed the data	Formal analysis	YES
5240399	28095783	JHC	PLoS52	designed the research and obtained funding for this research|wrote the paper|analyzed the data|had primary responsibility for the final content	had primary responsibility for the final content	-	-	NO
5240399	28095783	JMO	PLoS52	wrote the paper|analyzed the data	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5240399	28095783	JMO	PLoS52	wrote the paper|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5240399	28095783	LGC	PLoS52	performed the experiments|wrote the paper|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5240399	28095783	LGC	PLoS52	performed the experiments|wrote the paper|analyzed the data	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5240399	28095783	LGC	PLoS52	performed the experiments|wrote the paper|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5240399	28095783	MJ	PLoS52	designed the research and obtained funding for this research|analyzed the data|provided the animals	designed the research and obtained funding for this research	Conceived and designed the experiments	Funding acquisition|Methodology	YES
5240399	28095783	MJ	PLoS52	designed the research and obtained funding for this research|analyzed the data|provided the animals	analyzed the data	Analyzed the data	Formal analysis	YES
5240399	28095783	MJ	PLoS52	designed the research and obtained funding for this research|analyzed the data|provided the animals	provided the animals	-	-	NO
5240399	28095783	MS	PLoS52	designed the research and obtained funding for this research|wrote the paper|analyzed the data	designed the research and obtained funding for this research	Conceived and designed the experiments	Funding acquisition|Methodology	YES
5240399	28095783	MS	PLoS52	designed the research and obtained funding for this research|wrote the paper|analyzed the data	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5240399	28095783	MS	PLoS52	designed the research and obtained funding for this research|wrote the paper|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5240399	28095783	PS	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5240399	28095783	RMH	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
4404348	25894230	GS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404348	25894230	GS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404348	25894230	GS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404348	25894230	YW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404348	25894230	YW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404348	25894230	YW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404348	25894230	YW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404348	25894230	YW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5835552	29337135	AWD	2	were involved in the conception and design of the study|were involved in study implementation|interpreted the data and provided important intellectual input	were involved in the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5835552	29337135	AWD	2	were involved in the conception and design of the study|were involved in study implementation|interpreted the data and provided important intellectual input	were involved in study implementation	Performed the experiments	Investigation	YES
5835552	29337135	AWD	2	were involved in the conception and design of the study|were involved in study implementation|interpreted the data and provided important intellectual input	interpreted the data and provided important intellectual input	Analyzed the data	Formal analysis	YES
5835552	29337135	FI	2	were involved in study implementation|wrote the first draft	were involved in study implementation	Performed the experiments	Investigation	YES
5835552	29337135	FI	2	were involved in study implementation|wrote the first draft	wrote the first draft	Wrote the paper	Writing - Original Draft	YES
5835552	29337135	HK	2	were involved in the conception and design of the study|were involved in study implementation|interpreted the data and provided important intellectual input|wrote the first draft	were involved in the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5835552	29337135	HK	2	were involved in the conception and design of the study|were involved in study implementation|interpreted the data and provided important intellectual input|wrote the first draft	were involved in study implementation	Performed the experiments	Investigation	YES
5835552	29337135	HK	2	were involved in the conception and design of the study|were involved in study implementation|interpreted the data and provided important intellectual input|wrote the first draft	interpreted the data and provided important intellectual input	Analyzed the data	Formal analysis	YES
5835552	29337135	HK	2	were involved in the conception and design of the study|were involved in study implementation|interpreted the data and provided important intellectual input|wrote the first draft	wrote the first draft	Wrote the paper	Writing - Original Draft	YES
5835552	29337135	KK	2	were involved in the conception and design of the study|were involved in study implementation|interpreted the data and provided important intellectual input|wrote the first draft	were involved in the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5835552	29337135	KK	2	were involved in the conception and design of the study|were involved in study implementation|interpreted the data and provided important intellectual input|wrote the first draft	were involved in study implementation	Performed the experiments	Investigation	YES
5835552	29337135	KK	2	were involved in the conception and design of the study|were involved in study implementation|interpreted the data and provided important intellectual input|wrote the first draft	interpreted the data and provided important intellectual input	Analyzed the data	Formal analysis	YES
5835552	29337135	KK	2	were involved in the conception and design of the study|were involved in study implementation|interpreted the data and provided important intellectual input|wrote the first draft	wrote the first draft	Wrote the paper	Writing - Original Draft	YES
5835552	29337135	LB	2	were involved in study implementation|did the data analysis	were involved in study implementation	Performed the experiments	Investigation	YES
5835552	29337135	LB	2	were involved in study implementation|did the data analysis	did the data analysis	Analyzed the data	Formal analysis	YES
5835552	29337135	LJ	2	were involved in study implementation	were involved in study implementation	Performed the experiments	Investigation	YES
5835552	29337135	NAI	2	were involved in the conception and design of the study|were involved in study implementation|did the data analysis|interpreted the data and provided important intellectual input|wrote the first draft	were involved in the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5835552	29337135	NAI	2	were involved in the conception and design of the study|were involved in study implementation|did the data analysis|interpreted the data and provided important intellectual input|wrote the first draft	were involved in study implementation	Performed the experiments	Investigation	YES
5835552	29337135	NAI	2	were involved in the conception and design of the study|were involved in study implementation|did the data analysis|interpreted the data and provided important intellectual input|wrote the first draft	did the data analysis	Analyzed the data	Formal analysis	YES
5835552	29337135	NAI	2	were involved in the conception and design of the study|were involved in study implementation|did the data analysis|interpreted the data and provided important intellectual input|wrote the first draft	interpreted the data and provided important intellectual input	Analyzed the data	Formal analysis	YES
5835552	29337135	NAI	2	were involved in the conception and design of the study|were involved in study implementation|did the data analysis|interpreted the data and provided important intellectual input|wrote the first draft	wrote the first draft	Wrote the paper	Writing - Original Draft	YES
5835552	29337135	NG	2	were involved in study implementation	were involved in study implementation	Performed the experiments	Investigation	YES
5835552	29337135	NN	2	were involved in the conception and design of the study|were involved in study implementation|interpreted the data and provided important intellectual input|wrote the first draft	were involved in the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5835552	29337135	NN	2	were involved in the conception and design of the study|were involved in study implementation|interpreted the data and provided important intellectual input|wrote the first draft	were involved in study implementation	Performed the experiments	Investigation	YES
5835552	29337135	NN	2	were involved in the conception and design of the study|were involved in study implementation|interpreted the data and provided important intellectual input|wrote the first draft	interpreted the data and provided important intellectual input	Analyzed the data	Formal analysis	YES
5835552	29337135	NN	2	were involved in the conception and design of the study|were involved in study implementation|interpreted the data and provided important intellectual input|wrote the first draft	wrote the first draft	Wrote the paper	Writing - Original Draft	YES
5835552	29337135	SV	2	were involved in the conception and design of the study|were involved in study implementation|did the data analysis|interpreted the data and provided important intellectual input|wrote the first draft	were involved in the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5835552	29337135	SV	2	were involved in the conception and design of the study|were involved in study implementation|did the data analysis|interpreted the data and provided important intellectual input|wrote the first draft	were involved in study implementation	Performed the experiments	Investigation	YES
5835552	29337135	SV	2	were involved in the conception and design of the study|were involved in study implementation|did the data analysis|interpreted the data and provided important intellectual input|wrote the first draft	did the data analysis	Analyzed the data	Formal analysis	YES
5835552	29337135	SV	2	were involved in the conception and design of the study|were involved in study implementation|did the data analysis|interpreted the data and provided important intellectual input|wrote the first draft	interpreted the data and provided important intellectual input	Analyzed the data	Formal analysis	YES
5835552	29337135	SV	2	were involved in the conception and design of the study|were involved in study implementation|did the data analysis|interpreted the data and provided important intellectual input|wrote the first draft	wrote the first draft	Wrote the paper	Writing - Original Draft	YES
5517453	28785275	All authors	2	listed have made a substantial, direct and intellectual contribution to the work, and approved it for publication	listed have made a substantial, direct and intellectual contribution to the work, and approved it for publication	-	-	NO
5597106	28975915	Bandana Saini	2	critically reviewed the questionnaire, content of workshop and the manuscript	critically reviewed the questionnaire, content of workshop and the manuscript	Wrote the paper	Writing - Review & Editing	YES
5597106	28975915	Craig Phillips	2	critically reviewed the questionnaire, content of workshop and the manuscript	critically reviewed the questionnaire, content of workshop and the manuscript	Wrote the paper	Writing - Review & Editing	YES
5597106	28975915	Gagandeep Kaur	2	designed questionnaire, content of the workshop and wrote the manuscript	designed questionnaire, content of the workshop and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
5597106	28975915	Keith Wong	2	critically reviewed the questionnaire, content of workshop and the manuscript	critically reviewed the questionnaire, content of workshop and the manuscript	Wrote the paper	Writing - Review & Editing	YES
5597106	28975915	Maya Saba	2	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5331021	28155205	AV	2	were involved in the design and planning of the original actigraphy studies with inpatients	were involved in the design and planning of the original actigraphy studies with inpatients	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5331021	28155205	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5331021	28155205	GM	2	were involved in the design and planning of the original actigraphy studies with inpatients|identified the hypotheses for the current study	were involved in the design and planning of the original actigraphy studies with inpatients	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5331021	28155205	GM	2	were involved in the design and planning of the original actigraphy studies with inpatients|identified the hypotheses for the current study	identified the hypotheses for the current study	Performed the experiments	Investigation	YES
5331021	28155205	JS	2	identified the hypotheses for the current study|undertook the statistical analyses for this study and wrote the preliminary draft of the manuscript	identified the hypotheses for the current study	Performed the experiments	Investigation	YES
5331021	28155205	JS	2	identified the hypotheses for the current study|undertook the statistical analyses for this study and wrote the preliminary draft of the manuscript	undertook the statistical analyses for this study and wrote the preliminary draft of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5331021	28155205	KG	2	identified the hypotheses for the current study	identified the hypotheses for the current study	Performed the experiments	Investigation	YES
5331021	28155205	KKG	2	were involved in the design and planning of the original actigraphy studies with inpatients	were involved in the design and planning of the original actigraphy studies with inpatients	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5331021	28155205	OBF	2	were involved in the design and planning of the original actigraphy studies with inpatients	were involved in the design and planning of the original actigraphy studies with inpatients	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4878848	27257483	Emad Hamdy Gad	7	Study design, data collection and writing. Mohammed Alsayed abdelsamee: Data collection and data analysis	Study design, data collection and writing. Mohammed Alsayed abdelsamee: Data collection and data analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology	YES
4878848	27257483	Yasmin Kamel	7	Data collection	Data collection	Performed the experiments	Investigation	YES
4610955	26480927	ARZ	2	were responsible for the planning and conceptualization of the manuscript|were responsible for the writing	were responsible for the planning and conceptualization of the manuscript	Conceived and designed the experiments	Conceptualization|Methodology	YES
4610955	26480927	ARZ	2	were responsible for the planning and conceptualization of the manuscript|were responsible for the writing	were responsible for the writing	Wrote the paper	-	YES
4610955	26480927	All authors	2	revised, read and approved the final version of the manuscript	revised, read and approved the final version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4610955	26480927	KC	2	were responsible for the planning and conceptualization of the manuscript|were responsible for the writing	were responsible for the planning and conceptualization of the manuscript	Conceived and designed the experiments	Conceptualization|Methodology	YES
4610955	26480927	KC	2	were responsible for the planning and conceptualization of the manuscript|were responsible for the writing	were responsible for the writing	Wrote the paper	-	YES
4610955	26480927	OG	2	were responsible for the planning and conceptualization of the manuscript	were responsible for the planning and conceptualization of the manuscript	Conceived and designed the experiments	Conceptualization|Methodology	YES
5371231	28351430	All authors	2	contributed to the writing of the paper|read and approved the final manuscript	contributed to the writing of the paper	Wrote the paper	Writing - Original Draft	YES
5371231	28351430	All authors	2	contributed to the writing of the paper|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5371231	28351430	EM	2	worked on data cleaning, analysis and interpretation of results	worked on data cleaning, analysis and interpretation of results	Performed the experiments|Analyzed the data	Data curation|Formal analysis	YES
5371231	28351430	FM	2	advised on the methods and participated in the review of the manuscript	advised on the methods and participated in the review of the manuscript	Performed the experiments|Wrote the paper	Writing - Review & Editing	YES
5371231	28351430	HS	2	lead author, lead the development, monitored implementation of the study, data collection, analysis, and interpretation of the results	lead author, lead the development, monitored implementation of the study, data collection, analysis, and interpretation of the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Supervision	YES
5371231	28351430	JK	2	reviewed and advised on the design, analysis and interpretation of findings	reviewed and advised on the design, analysis and interpretation of findings	Conceived and designed the experiments|Analyzed the data	Formal analysis	YES
5371231	28351430	JT	2	principle investigator	principle investigator	-	-	NO
5371231	28351430	MCSF	2	assisted in development of data collection tools, consent forms the proposal, reviewing and redrafting some of the sections of the paper	assisted in development of data collection tools, consent forms the proposal, reviewing and redrafting some of the sections of the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5371231	28351430	MS	2	worked on reviewing and ensuring consents and study tools are in a clear local language, supervised proper data confidentiality and management at the sites	worked on reviewing and ensuring consents and study tools are in a clear local language, supervised proper data confidentiality and management at the sites	Performed the experiments	Supervision	YES
5371231	28351430	SK	2	contributed on reviewing the proposal, consents development, supervising the implementation of the study, she also participated in the review and editing of the paper	contributed on reviewing the proposal, consents development, supervising the implementation of the study, she also participated in the review and editing of the paper	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
4404349	25893499	AJF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404349	25893499	AJF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404349	25893499	AJF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404349	25893499	AJF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404349	25893499	BJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404349	25893499	BJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404349	25893499	BJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404349	25893499	BJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404349	25893499	RMS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404349	25893499	RMS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404349	25893499	RMS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404349	25893499	RMS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404349	25893499	TS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4404349	25893499	TS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5597107	28975916	Each author	2	reviewed the final version of the paper	reviewed the final version of the paper	Wrote the paper	Writing - Review & Editing	YES
5597107	28975916	Ibolja Cernak	2	finalized the manuscript in its present form	finalized the manuscript in its present form	Wrote the paper	Writing - Review & Editing	YES
5597107	28975916	Jeffrey Cies	2	identified molecules available from the british national formulary that may be suitable for clinical trials	identified molecules available from the british national formulary that may be suitable for clinical trials	Performed the experiments	Investigation	YES
5597107	28975916	Raimar Lobenberg	2	identified novel formulation methodologies and matched them to the bcs classification system to determine potential targets for mass production	identified novel formulation methodologies and matched them to the bcs classification system to determine potential targets for mass production	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
5597107	28975916	Richard Parrish	2	finalized the manuscript in its present form	finalized the manuscript in its present form	Wrote the paper	Writing - Review & Editing	YES
5597107	28975916	Robert MacArthur	2	identified novel formulation methodologies and matched them to the bcs classification system to determine potential targets for mass production	identified novel formulation methodologies and matched them to the bcs classification system to determine potential targets for mass production	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
5597107	28975916	Varsha Bhatt-Mehta	2	finalized the manuscript in its present form	finalized the manuscript in its present form	Wrote the paper	Writing - Review & Editing	YES
5240420	28095800	AJL	2	conceived the experiments, organized the research team, and revised and edited the manuscript	conceived the experiments, organized the research team, and revised and edited the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5240420	28095800	APA	2	conceived the experiments, organized the research team, and revised and edited the manuscript	conceived the experiments, organized the research team, and revised and edited the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5240420	28095800	JCL	2	performed the experiments and analyzed the data|drafted the manuscript	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5240420	28095800	JCL	2	performed the experiments and analyzed the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5240420	28095800	KR	2	drafted the manuscript|conceived the experiments, organized the research team, and revised and edited the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5240420	28095800	KR	2	drafted the manuscript|conceived the experiments, organized the research team, and revised and edited the manuscript	conceived the experiments, organized the research team, and revised and edited the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5240420	28095800	RMC	2	provided advice and statistical approaches for data analyses	provided advice and statistical approaches for data analyses	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5240420	28095800	XC	2	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5240420	28095800	YH-B	2	performed the experiments and analyzed the data|drafted the manuscript	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5240420	28095800	YH-B	2	performed the experiments and analyzed the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4887560	27284401	All authors	2	did literature search and agreed eligible papers	did literature search and agreed eligible papers	-	Formal analysis	YES
4887560	27284401	L. Tian	2	extracted data from involved publications	extracted data from involved publications	Performed the experiments	Investigation	YES
4887560	27284401	T. Wang	2	designed and performed the study|extracted data from involved publications	designed and performed the study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4887560	27284401	T. Wang	2	designed and performed the study|extracted data from involved publications	extracted data from involved publications	Performed the experiments	Investigation	YES
4887560	27284401	Y. Xue	2	directed and supervised the study	directed and supervised the study	-	Supervision	YES
5835554	29342444	JZ	2	planned the project and wrote the manuscript	planned the project and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5835554	29342444	LM	2	assisted in bioinformatic analyses	assisted in bioinformatic analyses	Analyzed the data	Formal analysis	YES
5835554	29342444	MJW	2	planned the project and wrote the manuscript	planned the project and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5835554	29342444	MP	2	reviewed incidence data and conducted statistical analyses	reviewed incidence data and conducted statistical analyses	Analyzed the data	Formal analysis	YES
5835554	29342444	MRD	2	conducted bioinformatic analyses, planned and wrote the manuscript	conducted bioinformatic analyses, planned and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
4612469	26486200	ISO	PLoS5	Conceived and designed experiments|Performed the experiments|Analyzed the data|Wrote the manuscript	Conceived and designed experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4612469	26486200	ISO	PLoS5	Conceived and designed experiments|Performed the experiments|Analyzed the data|Wrote the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4612469	26486200	ISO	PLoS5	Conceived and designed experiments|Performed the experiments|Analyzed the data|Wrote the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4612469	26486200	ISO	PLoS5	Conceived and designed experiments|Performed the experiments|Analyzed the data|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4612469	26486200	JSM	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4612469	26486200	LCHG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4612469	26486200	LTB	PLoS5	Analyzed the data|Wrote the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4612469	26486200	LTB	PLoS5	Analyzed the data|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4612469	26486200	MMA	PLoS5	Conceived and designed experiments|Analyzed the data|Wrote the manuscript	Conceived and designed experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4612469	26486200	MMA	PLoS5	Conceived and designed experiments|Analyzed the data|Wrote the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4612469	26486200	MMA	PLoS5	Conceived and designed experiments|Analyzed the data|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4612469	26486200	ROG	PLoS5	Performed the experiments|Wrote the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4612469	26486200	ROG	PLoS5	Performed the experiments|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4612469	26486200	SPP	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5332323	28168632	AL	2	participated in the design of the study	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
5332323	28168632	AP	2	participated in the design of the study|contributed to the data interpretation and contributed to the drafting and revisions of the manuscript	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
5332323	28168632	AP	2	participated in the design of the study|contributed to the data interpretation and contributed to the drafting and revisions of the manuscript	contributed to the data interpretation and contributed to the drafting and revisions of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5332323	28168632	AT	2	contributed to the data interpretation and contributed to the drafting and revisions of the manuscript	contributed to the data interpretation and contributed to the drafting and revisions of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5332323	28168632	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5332323	28168632	JC	2	participated in the design of the study|contributed to the data interpretation and contributed to the drafting and revisions of the manuscript	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
5332323	28168632	JC	2	participated in the design of the study|contributed to the data interpretation and contributed to the drafting and revisions of the manuscript	contributed to the data interpretation and contributed to the drafting and revisions of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5332323	28168632	JT	2	contributed to the data interpretation and contributed to the drafting and revisions of the manuscript	contributed to the data interpretation and contributed to the drafting and revisions of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5332323	28168632	RS	2	participated in the design of the study|contributed to the data interpretation and contributed to the drafting and revisions of the manuscript	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
5332323	28168632	RS	2	participated in the design of the study|contributed to the data interpretation and contributed to the drafting and revisions of the manuscript	contributed to the data interpretation and contributed to the drafting and revisions of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5332323	28168632	YM	2	performed the statistical analysis|contributed to the data interpretation and contributed to the drafting and revisions of the manuscript	performed the statistical analysis	Analyzed the data	Formal analysis	YES
5332323	28168632	YM	2	performed the statistical analysis|contributed to the data interpretation and contributed to the drafting and revisions of the manuscript	contributed to the data interpretation and contributed to the drafting and revisions of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5517461	28775726	All authors	PLoS52	contributed to the data analysis	contributed to the data analysis	Analyzed the data	Formal analysis	YES
5517461	28775726	DK	PLoS52	provided technical guidance for analysis of proteomics	provided technical guidance for analysis of proteomics	-	Supervision	YES
5517461	28775726	GJ	PLoS52	designed the experiments|wrote the paper	designed the experiments	Conceived and designed the experiments	Methodology	YES
5517461	28775726	GJ	PLoS52	designed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5517461	28775726	JS	PLoS52	provided technical guidance for analysis of proteomics	provided technical guidance for analysis of proteomics	-	Supervision	YES
5517461	28775726	MK	PLoS52	carried out analyses of leaf weight and area	carried out analyses of leaf weight and area	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5517461	28775726	MM	PLoS52	designed the experiments|grew plants, extracted proteins, performed physiological measurements and analyzed data|wrote the paper	designed the experiments	Conceived and designed the experiments	Methodology	YES
5517461	28775726	MM	PLoS52	designed the experiments|grew plants, extracted proteins, performed physiological measurements and analyzed data|wrote the paper	grew plants, extracted proteins, performed physiological measurements and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5517461	28775726	MM	PLoS52	designed the experiments|grew plants, extracted proteins, performed physiological measurements and analyzed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5517461	28775726	RO	PLoS52	performed mass spectrometry and sample preparation	performed mass spectrometry and sample preparation	Performed the experiments	Investigation	YES
5517461	28775726	SH	PLoS52	provided technical guidance for analysis of proteomics	provided technical guidance for analysis of proteomics	-	Supervision	YES
5379736	28376825	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5379736	28376825	CK	2	supervised the study	supervised the study	-	Supervision	YES
5379736	28376825	DS	2	provided technical support	provided technical support	Performed the experiments	Investigation	YES
5379736	28376825	ET	2	drafted and revised the manuscript	drafted and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5379736	28376825	JL	2	supervised the study	supervised the study	-	Supervision	YES
5379736	28376825	JYN	2	provided technical support	provided technical support	Performed the experiments	Investigation	YES
5379736	28376825	MAPND	2	conducted the study|drafted and revised the manuscript	conducted the study	Performed the experiments	Investigation	YES
5379736	28376825	MAPND	2	conducted the study|drafted and revised the manuscript	drafted and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5597108	28975917	C. J. Louizos	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5597108	28975917	Peter K. Knight	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5517488	28775734	HL	PLoS52	performed research|wrote the paper	performed research	Performed the experiments	Investigation	YES
5517488	28775734	HL	PLoS52	performed research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5517488	28775734	KL	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
5517488	28775734	KR	PLoS52	performed research|wrote the paper	performed research	Performed the experiments	Investigation	YES
5517488	28775734	KR	PLoS52	performed research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5517488	28775734	MW	PLoS52	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5517488	28775734	WW	PLoS52	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5517488	28775734	XS	PLoS52	designed the research|wrote the paper	designed the research	Conceived and designed the experiments	Methodology	YES
5517488	28775734	XS	PLoS52	designed the research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5517488	28775734	XW	PLoS52	performed research|analyzed data|wrote the paper	performed research	Performed the experiments	Investigation	YES
5517488	28775734	XW	PLoS52	performed research|analyzed data|wrote the paper	analyzed data	Analyzed the data	Formal analysis	YES
5517488	28775734	XW	PLoS52	performed research|analyzed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404350	25893670	AS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4404350	25893670	AS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404350	25893670	AT	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4404350	25893670	FM	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404350	25893670	FM	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404350	25893670	LS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4404350	25893670	LS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4404350	25893670	LS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404350	25893670	MC	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404350	25893670	MC	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404350	25893670	ML	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4404350	25893670	ML	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404350	25893670	MT	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404350	25893670	MT	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404350	25893670	PC	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404350	25893670	PC	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404350	25893670	SF	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4404350	25893670	SF	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4900296	27330742	A Azab	7	Acquisition, analysis, and interpretation of data. * Drafting the work. * Final approval of the version published. * Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved. Ashraf M. Shahin, Akram	Acquisition, analysis, and interpretation of data. * Drafting the work. * Final approval of the version published. * Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved. Ashraf M. Shahin, Akram	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Formal analysis|Investigation|Writing - Original Draft	YES
4900296	27330742	A. Abdallah	7	Substantial contributions to the conception and design of the work. * Drafting the work and revising it critically for important intellectual content. * Final approval of the version published. * Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved. Mostafa A Salama, Soha A Ebrahim, Ahmad	Substantial contributions to the conception and design of the work. * Drafting the work and revising it critically for important intellectual content. * Final approval of the version published. * Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved. Mostafa A Salama, Soha A Ebrahim, Ahmad	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
4900296	27330742	E El-Sadek	7	Acquisition, analysis, and interpretation of data. * Revising the work critically for important intellectual content. * Final approval of the version published. * Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved. Waleid E Abdulghani, Laila M Sherief. * Acquisition, analysis, and interpretation of data. * Drafting the work. * Final approval of the version published. * Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Acquisition, analysis, and interpretation of data. * Revising the work critically for important intellectual content. * Final approval of the version published. * Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved. Waleid E Abdulghani, Laila M Sherief. * Acquisition, analysis, and interpretation of data. * Drafting the work. * Final approval of the version published. * Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Formal analysis|Investigation|Writing - Original Draft	YES
5240438	28095777	FQL	2	performed the experiments and helped analyse the data	performed the experiments and helped analyse the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5240438	28095777	KX	2	helped analyse the data and prepared the manuscript	helped analyse the data and prepared the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5240438	28095777	LL	2	designed the experiments, guided the analysis and prepared the manuscript	designed the experiments, guided the analysis and prepared the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Original Draft	YES
5240438	28095777	MHW	2	performed the experiments, analysed the data and prepared the manuscript	performed the experiments, analysed the data and prepared the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4615801	26493863	ADS	PLoS52	contributed significantly to the study design|critically edited the manuscript	contributed significantly to the study design	Conceived and designed the experiments	Methodology	YES
4615801	26493863	ADS	PLoS52	contributed significantly to the study design|critically edited the manuscript	critically edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
4615801	26493863	AO	PLoS52	contributed significantly to the study design	contributed significantly to the study design	Conceived and designed the experiments	Methodology	YES
4615801	26493863	All authors	PLoS52	read and approved the manuscript	read and approved the manuscript	-	-	NO
4615801	26493863	BK	PLoS52	conducted the fgds and interviews|analyzed the data	conducted the fgds and interviews	Performed the experiments	Investigation	YES
4615801	26493863	BK	PLoS52	conducted the fgds and interviews|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
4615801	26493863	DO	PLoS52	contributed significantly to the study design|discussed full texts|critically edited the manuscript|is the guarantor of the paper	contributed significantly to the study design	Conceived and designed the experiments	Methodology	YES
4615801	26493863	DO	PLoS52	contributed significantly to the study design|discussed full texts|critically edited the manuscript|is the guarantor of the paper	discussed full texts	-	-	NO
4615801	26493863	DO	PLoS52	contributed significantly to the study design|discussed full texts|critically edited the manuscript|is the guarantor of the paper	critically edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
4615801	26493863	DO	PLoS52	contributed significantly to the study design|discussed full texts|critically edited the manuscript|is the guarantor of the paper	is the guarantor of the paper	-	-	NO
4615801	26493863	EG	PLoS52	contributed significantly to the study design	contributed significantly to the study design	Conceived and designed the experiments	Methodology	YES
4615801	26493863	EJS	PLoS52	contributed significantly to the study design|conceived the study|discussed full texts	contributed significantly to the study design	Conceived and designed the experiments	Methodology	YES
4615801	26493863	EJS	PLoS52	contributed significantly to the study design|conceived the study|discussed full texts	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4615801	26493863	EJS	PLoS52	contributed significantly to the study design|conceived the study|discussed full texts	discussed full texts	-	-	NO
4615801	26493863	EMvdE	PLoS52	contributed significantly to the study design|conceived the study|analyzed the data|discussed full texts|drafted the manuscript	contributed significantly to the study design	Conceived and designed the experiments	Methodology	YES
4615801	26493863	EMvdE	PLoS52	contributed significantly to the study design|conceived the study|analyzed the data|discussed full texts|drafted the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4615801	26493863	EMvdE	PLoS52	contributed significantly to the study design|conceived the study|analyzed the data|discussed full texts|drafted the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
4615801	26493863	EMvdE	PLoS52	contributed significantly to the study design|conceived the study|analyzed the data|discussed full texts|drafted the manuscript	discussed full texts	-	-	NO
4615801	26493863	EMvdE	PLoS52	contributed significantly to the study design|conceived the study|analyzed the data|discussed full texts|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4615801	26493863	HM	PLoS52	contributed significantly to the study design	contributed significantly to the study design	Conceived and designed the experiments	Methodology	YES
4615801	26493863	SMG	PLoS52	contributed significantly to the study design|discussed full texts|critically edited the manuscript	contributed significantly to the study design	Conceived and designed the experiments	Methodology	YES
4615801	26493863	SMG	PLoS52	contributed significantly to the study design|discussed full texts|critically edited the manuscript	discussed full texts	-	-	NO
4615801	26493863	SMG	PLoS52	contributed significantly to the study design|discussed full texts|critically edited the manuscript	critically edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5835568	29396294	DD	2	designed and supervised the study, analyzed the data and revised the manuscript	designed and supervised the study, analyzed the data and revised the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Supervision|Writing - Review & Editing	YES
5835568	29396294	DG	2	coordinated the study, analyzed the data and drafted the manuscript	coordinated the study, analyzed the data and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Project administration|Writing - Original Draft	YES
5835568	29396294	FB	2	revised the manuscript critically for important intellectual content	revised the manuscript critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5835568	29396294	HG	2	coordinated the study, analyzed the data and drafted the manuscript	coordinated the study, analyzed the data and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Project administration|Writing - Original Draft	YES
5835568	29396294	JD	2	processed tcga data	processed tcga data	Analyzed the data	Data curation	YES
5835568	29396294	JL	2	revised the manuscript critically for important intellectual content	revised the manuscript critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5835568	29396294	LKR	2	analyzed the data and drafted the manuscript	analyzed the data and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4475557	26137486	All authors	2	listed have contributed substantially to the paper	listed have contributed substantially to the paper	-	-	NO
4475557	26137486	Elzbieta Skorupska	2	contributed conception and design of the work, acquisition of data, interpretation of data, and drafting the paper	contributed conception and design of the work, acquisition of data, interpretation of data, and drafting the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Resources|Writing - Original Draft	YES
4475557	26137486	Michal Rychlik	2	contributed conception and design of the work, acquisition of data, analysis of data, and drafting the paper	contributed conception and design of the work, acquisition of data, analysis of data, and drafting the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Resources|Writing - Original Draft	YES
4475557	26137486	Wlodzimierz Samborski	2	contributed correction and final approval of the resubmitted version	contributed correction and final approval of the resubmitted version	-	-	NO
4404351	25893826	HC	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404351	25893826	HC	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404351	25893826	JX	PLoS5	Performed the experiments|Contributed to the drawing of the figures for the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4404351	25893826	JX	PLoS5	Performed the experiments|Contributed to the drawing of the figures for the manuscript	Contributed to the drawing of the figures for the manuscript	-	Visualization	YES
4404351	25893826	LL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to the drawing of the figures for the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404351	25893826	LL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to the drawing of the figures for the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4404351	25893826	LL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to the drawing of the figures for the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404351	25893826	LL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to the drawing of the figures for the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404351	25893826	LL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to the drawing of the figures for the manuscript	Contributed to the drawing of the figures for the manuscript	-	Visualization	YES
4404351	25893826	QL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404351	25893826	TZ	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4404351	25893826	XL	PLoS5	Performed the experiments|Contributed to the drawing of the figures for the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4404351	25893826	XL	PLoS5	Performed the experiments|Contributed to the drawing of the figures for the manuscript	Contributed to the drawing of the figures for the manuscript	-	Visualization	YES
5597109	28975918	Agnieska Skowron	2	helped with distribution of the survey	helped with distribution of the survey	Performed the experiments	Investigation	YES
5597109	28975918	Annie Marcincal	2	helped with distribution of the survey	helped with distribution of the survey	Performed the experiments	Investigation	YES
5597109	28975918	Antonio Sanchez Pozo	2	developed the questionnaire|helped with distribution of the survey|provided useful criticism and suggestions during revision of the manuscript	developed the questionnaire	-	-	NO
5597109	28975918	Antonio Sanchez Pozo	2	developed the questionnaire|helped with distribution of the survey|provided useful criticism and suggestions during revision of the manuscript	helped with distribution of the survey	Performed the experiments	Investigation	YES
5597109	28975918	Antonio Sanchez Pozo	2	developed the questionnaire|helped with distribution of the survey|provided useful criticism and suggestions during revision of the manuscript	provided useful criticism and suggestions during revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5597109	28975918	Borut Bozic	2	helped with distribution of the survey|provided useful criticism and suggestions during revision of the manuscript	helped with distribution of the survey	Performed the experiments	Investigation	YES
5597109	28975918	Borut Bozic	2	helped with distribution of the survey|provided useful criticism and suggestions during revision of the manuscript	provided useful criticism and suggestions during revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5597109	28975918	Chris van Schravendijk	2	assured the contacts with medine2	assured the contacts with medine2	-	-	NO
5597109	28975918	Constantin Mircioiu	2	played a major role in the statistical analyses of the data	played a major role in the statistical analyses of the data	Analyzed the data	Formal analysis	YES
5597109	28975918	Dimitrios Rekkas	2	developed the questionnaire|helped with distribution of the survey	developed the questionnaire	-	-	NO
5597109	28975918	Dimitrios Rekkas	2	developed the questionnaire|helped with distribution of the survey	helped with distribution of the survey	Performed the experiments	Investigation	YES
5597109	28975918	Jeffrey Atkinson	2	designed, constructed, ran and analysed the survey, and wrote the paper	designed, constructed, ran and analysed the survey, and wrote the paper	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5597109	28975918	Jouni Hirvonen	2	helped with distribution of the survey	helped with distribution of the survey	Performed the experiments	Investigation	YES
5597109	28975918	Kristien De Paepe	2	ran the phar-qa consortium	ran the phar-qa consortium	Performed the experiments	Investigation	YES
5366290	28188565	Abbott Laboratories	1	Health as well as grant support from|Calabrese has served as a consultant/advisory board member/speaker for	Health as well as grant support from	-	Funding acquisition	YES
5366290	28188565	Abbott Laboratories	1	Health as well as grant support from|Calabrese has served as a consultant/advisory board member/speaker for	Calabrese has served as a consultant/advisory board member/speaker for	-	-	NO
5517489	28775727	AL	2	performed the experiments and wrote the manuscript	performed the experiments and wrote the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5517489	28775727	DA	2	conducted potato transformation and analysis	conducted potato transformation and analysis	Performed the experiments	Investigation	YES
5517489	28775727	HC	2	conceived and designed the study and wrote the manuscript	conceived and designed the study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
5517489	28775727	HK	2	conceived and designed the study and wrote the manuscript	conceived and designed the study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
5517489	28775727	HP	2	performed the experiments and wrote the manuscript	performed the experiments and wrote the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5517489	28775727	JA	2	contributed to scientific discussions and revision of the manuscript	contributed to scientific discussions and revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5517489	28775727	KM	2	performed the experiments and wrote the manuscript	performed the experiments and wrote the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5517489	28775727	SL	2	conducted potato transformation and analysis	conducted potato transformation and analysis	Performed the experiments	Investigation	YES
5379739	28376815	Alienah Mpahleni	PLoS52	for their time and dedication throughout the study	for their time and dedication throughout the study	-	-	NO
5379739	28376815	All authors	PLoS52	had full access to the study data|have approved this final version|read and approved the final manuscript	had full access to the study data	-	-	NO
5379739	28376815	All authors	PLoS52	had full access to the study data|have approved this final version|read and approved the final manuscript	have approved this final version	-	-	NO
5379739	28376815	All authors	PLoS52	had full access to the study data|have approved this final version|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5379739	28376815	Anna Arnaudo	PLoS52	for her proficient editing skills	for her proficient editing skills	Wrote the paper	Writing - Review & Editing	YES
5379739	28376815	CO	PLoS52	conceptualised the study|ran the study and collected/collated the data|analysed the data|wrote the original manuscript and all authors read and contributed to each version	conceptualised the study	Conceived and designed the experiments	Conceptualization	YES
5379739	28376815	CO	PLoS52	conceptualised the study|ran the study and collected/collated the data|analysed the data|wrote the original manuscript and all authors read and contributed to each version	ran the study and collected/collated the data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5379739	28376815	CO	PLoS52	conceptualised the study|ran the study and collected/collated the data|analysed the data|wrote the original manuscript and all authors read and contributed to each version	analysed the data	Analyzed the data	Formal analysis	YES
5379739	28376815	CO	PLoS52	conceptualised the study|ran the study and collected/collated the data|analysed the data|wrote the original manuscript and all authors read and contributed to each version	wrote the original manuscript and all authors read and contributed to each version	Wrote the paper	Writing - Original Draft	YES
5379739	28376815	Christie Heiberg	PLoS52	for their time and dedication throughout the study	for their time and dedication throughout the study	-	-	NO
5379739	28376815	DB	PLoS52	conceptualised the study	conceptualised the study	Conceived and designed the experiments	Conceptualization	YES
5379739	28376815	GM	PLoS52	conceptualised the study	conceptualised the study	Conceived and designed the experiments	Conceptualization	YES
5379739	28376815	HIV	PLoS52	drug resistance genotyping	drug resistance genotyping	Performed the experiments	Investigation	YES
5379739	28376815	Heidi Freislich	PLoS52	for their time and dedication throughout the study	for their time and dedication throughout the study	-	-	NO
5379739	28376815	KC	PLoS52	conceptualised the study|analysed the data	conceptualised the study	Conceived and designed the experiments	Conceptualization	YES
5379739	28376815	KC	PLoS52	conceptualised the study|analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
5379739	28376815	Monica Vogt	PLoS52	for their time and dedication throughout the study	for their time and dedication throughout the study	-	-	NO
5379739	28376815	Nomsa Ngwenya	PLoS52	for their time and dedication throughout the study	for their time and dedication throughout the study	-	-	NO
5379739	28376815	RL	PLoS52	analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
5379739	28376815	RW	PLoS52	conceptualised the study	conceptualised the study	Conceived and designed the experiments	Conceptualization	YES
5379739	28376815	Speech Mzamo	PLoS52	for their time and dedication throughout the study	for their time and dedication throughout the study	-	-	NO
5379739	28376815	The authors	PLoS52	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5379739	28376815	UCT	PLoS52	for the drug assays	for the drug assays	Performed the experiments	Investigation	YES
4623278	26507824	AG	2	contributed to collection, analysis, and interpretation of the data, and revised the manuscript	contributed to collection, analysis, and interpretation of the data, and revised the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Review & Editing	YES
4623278	26507824	AH	2	contributed to collection, analysis, and interpretation of the data, and revised the manuscript	contributed to collection, analysis, and interpretation of the data, and revised the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Review & Editing	YES
4623278	26507824	BD	2	contributed to collection, analysis, and interpretation of the data, and revised the manuscript	contributed to collection, analysis, and interpretation of the data, and revised the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Review & Editing	YES
4623278	26507824	CK	2	contributed to data collection, interpretation of results, and revision of the manuscript	contributed to data collection, interpretation of results, and revision of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
4623278	26507824	ED	2	contributed to collection, analysis, and interpretation of the data, and revised the manuscript	contributed to collection, analysis, and interpretation of the data, and revised the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Review & Editing	YES
4623278	26507824	EG	2	conceptualised and designed the study	conceptualised and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4623278	26507824	HCD	2	conceptualised and designed the study	conceptualised and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4623278	26507824	PN	2	contributed to data collection, interpretation of results, and revision of the manuscript	contributed to data collection, interpretation of results, and revision of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
4623278	26507824	TAO	2	contributed to data collection, analysed, and interpreted the data and drafted the manuscript	contributed to data collection, analysed, and interpreted the data and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5241962	28100184	JM	2	conceived the experiment|obtained the funding allowing to perform the experiment and scientific work|helped with the wrote most of the manuscript with	conceived the experiment	Conceived and designed the experiments	Conceptualization	YES
5241962	28100184	JM	2	conceived the experiment|obtained the funding allowing to perform the experiment and scientific work|helped with the wrote most of the manuscript with	obtained the funding allowing to perform the experiment and scientific work	Performed the experiments	Funding acquisition|Investigation	YES
5241962	28100184	JM	2	conceived the experiment|obtained the funding allowing to perform the experiment and scientific work|helped with the wrote most of the manuscript with	helped with the wrote most of the manuscript with	Wrote the paper	Writing - Original Draft	YES
5241962	28100184	JP	2	conceived the experiment|helped with the performed and supervised all laboratory work with|developed the bioinformatics pipeline and performed bioinformatics, statistical and enrichment analyses|wrote most of the manuscript with	conceived the experiment	Conceived and designed the experiments	Conceptualization	YES
5241962	28100184	JP	2	conceived the experiment|helped with the performed and supervised all laboratory work with|developed the bioinformatics pipeline and performed bioinformatics, statistical and enrichment analyses|wrote most of the manuscript with	helped with the performed and supervised all laboratory work with	Performed the experiments	Investigation|Supervision	YES
5241962	28100184	JP	2	conceived the experiment|helped with the performed and supervised all laboratory work with|developed the bioinformatics pipeline and performed bioinformatics, statistical and enrichment analyses|wrote most of the manuscript with	developed the bioinformatics pipeline and performed bioinformatics, statistical and enrichment analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5241962	28100184	JP	2	conceived the experiment|helped with the performed and supervised all laboratory work with|developed the bioinformatics pipeline and performed bioinformatics, statistical and enrichment analyses|wrote most of the manuscript with	wrote most of the manuscript with	Wrote the paper	Writing - Original Draft	YES
5241962	28100184	SC	2	conceived the experiment|performed and supervised all laboratory work with|helped with the wrote most of the manuscript with	conceived the experiment	Conceived and designed the experiments	Conceptualization	YES
5241962	28100184	SC	2	conceived the experiment|performed and supervised all laboratory work with|helped with the wrote most of the manuscript with	performed and supervised all laboratory work with	Performed the experiments	Investigation|Supervision	YES
5241962	28100184	SC	2	conceived the experiment|performed and supervised all laboratory work with|helped with the wrote most of the manuscript with	helped with the wrote most of the manuscript with	Wrote the paper	Writing - Original Draft	YES
4916047	27358728	B Oakley	7	study design, data analysis/interpretation, writing	study design, data analysis/interpretation, writing	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology	YES
4916047	27358728	C Lamb	7	study design, data analysis/interpretation, writing	study design, data analysis/interpretation, writing	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology	YES
4916047	27358728	J Catton	7	study design, data interpretation, review	study design, data interpretation, review	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
4916047	27358728	R Vohra	7	paper writing and review	paper writing and review	Wrote the paper	Writing - Review & Editing	YES
4404352	25893581	GSG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404352	25893581	GSG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404352	25893581	GSG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404352	25893581	GSG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404352	25893581	HMB	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404352	25893581	HMB	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404352	25893581	RM	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404352	25893581	RM	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4475560	26137473	Daisuke Nishizawa	2	contributed equally to this study	contributed equally to this study	-	-	NO
4475560	26137473	Yoh Dobashi	2	contributed equally to this study	contributed equally to this study	-	-	NO
5597111	28975919	Jennifer Beall	PLoS52	conceived and designed the study|performed the experiment/study|wrote the paper	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5597111	28975919	Jennifer Beall	PLoS52	conceived and designed the study|performed the experiment/study|wrote the paper	performed the experiment/study	Performed the experiments	Investigation	YES
5597111	28975919	Jennifer Beall	PLoS52	conceived and designed the study|performed the experiment/study|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5597111	28975919	John Hensley	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5597111	28975919	Renee DeHart	PLoS52	conceived and designed the study|performed the experiment/study|analyzed the data|wrote the paper	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5597111	28975919	Renee DeHart	PLoS52	conceived and designed the study|performed the experiment/study|analyzed the data|wrote the paper	performed the experiment/study	Performed the experiments	Investigation	YES
5597111	28975919	Renee DeHart	PLoS52	conceived and designed the study|performed the experiment/study|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5597111	28975919	Renee DeHart	PLoS52	conceived and designed the study|performed the experiment/study|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5597111	28975919	Robert Riggs	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
4916050	27358727	HK	2	did the data collection|did the analysis and interpretation	did the data collection	Performed the experiments	Investigation	YES
4916050	27358727	HK	2	did the data collection|did the analysis and interpretation	did the analysis and interpretation	Analyzed the data	Formal analysis	YES
4916050	27358727	HU	2	contributed to the conception and design|did the data collection|did the writing of the article and the critical revisions	contributed to the conception and design	Conceived and designed the experiments	Conceptualization	YES
4916050	27358727	HU	2	contributed to the conception and design|did the data collection|did the writing of the article and the critical revisions	did the data collection	Performed the experiments	Investigation	YES
4916050	27358727	HU	2	contributed to the conception and design|did the data collection|did the writing of the article and the critical revisions	did the writing of the article and the critical revisions	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4916050	27358727	YN	2	did the data collection|did the analysis and interpretation	did the data collection	Performed the experiments	Investigation	YES
4916050	27358727	YN	2	did the data collection|did the analysis and interpretation	did the analysis and interpretation	Analyzed the data	Formal analysis	YES
5897918	29396306	AVN	2	designed and implemented the study|conducted data analyses	designed and implemented the study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5897918	29396306	AVN	2	designed and implemented the study|conducted data analyses	conducted data analyses	Analyzed the data	Formal analysis	YES
5897918	29396306	All authors	2	interpreted the data and critically revised the manuscript	interpreted the data and critically revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5897918	29396306	CLH	2	designed and implemented the study	designed and implemented the study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5897918	29396306	CML	2	designed and implemented the study	designed and implemented the study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5897918	29396306	EC	2	contributed equally to this paper|designed and implemented the study|conducted data analyses|had full access to all of the data in the study, and take responsibility for the integrity of the data and the accuracy of the data analysis|drafted the manuscript	contributed equally to this paper	-	-	NO
5897918	29396306	EC	2	contributed equally to this paper|designed and implemented the study|conducted data analyses|had full access to all of the data in the study, and take responsibility for the integrity of the data and the accuracy of the data analysis|drafted the manuscript	designed and implemented the study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5897918	29396306	EC	2	contributed equally to this paper|designed and implemented the study|conducted data analyses|had full access to all of the data in the study, and take responsibility for the integrity of the data and the accuracy of the data analysis|drafted the manuscript	conducted data analyses	Analyzed the data	Formal analysis	YES
5897918	29396306	EC	2	contributed equally to this paper|designed and implemented the study|conducted data analyses|had full access to all of the data in the study, and take responsibility for the integrity of the data and the accuracy of the data analysis|drafted the manuscript	had full access to all of the data in the study, and take responsibility for the integrity of the data and the accuracy of the data analysis	Analyzed the data	Data curation|Formal analysis	YES
5897918	29396306	EC	2	contributed equally to this paper|designed and implemented the study|conducted data analyses|had full access to all of the data in the study, and take responsibility for the integrity of the data and the accuracy of the data analysis|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5897918	29396306	EHE	2	contributed equally to this paper|conceived the study|designed and implemented the study|conducted data analyses|had full access to all of the data in the study, and take responsibility for the integrity of the data and the accuracy of the data analysis|drafted the manuscript	contributed equally to this paper	-	-	NO
5897918	29396306	EHE	2	contributed equally to this paper|conceived the study|designed and implemented the study|conducted data analyses|had full access to all of the data in the study, and take responsibility for the integrity of the data and the accuracy of the data analysis|drafted the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5897918	29396306	EHE	2	contributed equally to this paper|conceived the study|designed and implemented the study|conducted data analyses|had full access to all of the data in the study, and take responsibility for the integrity of the data and the accuracy of the data analysis|drafted the manuscript	designed and implemented the study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5897918	29396306	EHE	2	contributed equally to this paper|conceived the study|designed and implemented the study|conducted data analyses|had full access to all of the data in the study, and take responsibility for the integrity of the data and the accuracy of the data analysis|drafted the manuscript	conducted data analyses	Analyzed the data	Formal analysis	YES
5897918	29396306	EHE	2	contributed equally to this paper|conceived the study|designed and implemented the study|conducted data analyses|had full access to all of the data in the study, and take responsibility for the integrity of the data and the accuracy of the data analysis|drafted the manuscript	had full access to all of the data in the study, and take responsibility for the integrity of the data and the accuracy of the data analysis	Analyzed the data	Data curation|Formal analysis	YES
5897918	29396306	EHE	2	contributed equally to this paper|conceived the study|designed and implemented the study|conducted data analyses|had full access to all of the data in the study, and take responsibility for the integrity of the data and the accuracy of the data analysis|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5897918	29396306	GW	2	designed and implemented the study	designed and implemented the study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5897918	29396306	JC	2	conceived the study|designed and implemented the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5897918	29396306	JC	2	conceived the study|designed and implemented the study	designed and implemented the study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5897918	29396306	JKD	2	conducted data analyses	conducted data analyses	Analyzed the data	Formal analysis	YES
5897918	29396306	LTP	2	designed and implemented the study|conducted data analyses	designed and implemented the study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5897918	29396306	LTP	2	designed and implemented the study|conducted data analyses	conducted data analyses	Analyzed the data	Formal analysis	YES
5897918	29396306	MG	2	conceived the study|designed and implemented the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5897918	29396306	MG	2	conceived the study|designed and implemented the study	designed and implemented the study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5897918	29396306	NC	2	conducted data analyses|had full access to all of the data in the study, and take responsibility for the integrity of the data and the accuracy of the data analysis	conducted data analyses	Analyzed the data	Formal analysis	YES
5897918	29396306	NC	2	conducted data analyses|had full access to all of the data in the study, and take responsibility for the integrity of the data and the accuracy of the data analysis	had full access to all of the data in the study, and take responsibility for the integrity of the data and the accuracy of the data analysis	Analyzed the data	Data curation|Formal analysis	YES
5897918	29396306	RP	2	designed and implemented the study	designed and implemented the study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5897918	29396306	S-LCC	2	designed and implemented the study	designed and implemented the study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5897918	29396306	SE	2	designed and implemented the study	designed and implemented the study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5897918	29396306	SSF	2	designed and implemented the study	designed and implemented the study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5897918	29396306	STS	2	conceived the study|designed and implemented the study|conducted data analyses|had full access to all of the data in the study, and take responsibility for the integrity of the data and the accuracy of the data analysis|drafted the manuscript|is guarantor	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5897918	29396306	STS	2	conceived the study|designed and implemented the study|conducted data analyses|had full access to all of the data in the study, and take responsibility for the integrity of the data and the accuracy of the data analysis|drafted the manuscript|is guarantor	designed and implemented the study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5897918	29396306	STS	2	conceived the study|designed and implemented the study|conducted data analyses|had full access to all of the data in the study, and take responsibility for the integrity of the data and the accuracy of the data analysis|drafted the manuscript|is guarantor	conducted data analyses	Analyzed the data	Formal analysis	YES
5897918	29396306	STS	2	conceived the study|designed and implemented the study|conducted data analyses|had full access to all of the data in the study, and take responsibility for the integrity of the data and the accuracy of the data analysis|drafted the manuscript|is guarantor	had full access to all of the data in the study, and take responsibility for the integrity of the data and the accuracy of the data analysis	Analyzed the data	Data curation|Formal analysis	YES
5897918	29396306	STS	2	conceived the study|designed and implemented the study|conducted data analyses|had full access to all of the data in the study, and take responsibility for the integrity of the data and the accuracy of the data analysis|drafted the manuscript|is guarantor	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5897918	29396306	STS	2	conceived the study|designed and implemented the study|conducted data analyses|had full access to all of the data in the study, and take responsibility for the integrity of the data and the accuracy of the data analysis|drafted the manuscript|is guarantor	is guarantor	-	-	NO
5897918	29396306	STW	2	designed and implemented the study	designed and implemented the study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4631705	26530077	CSD	2	researched and wrote the manuscript	researched and wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5517496	28775731	AH	2	contributed in planning, designing and finalization of basic idea of experiment, overall supervision during analytical work, statistical analysis of data, revision and finalization of manuscript	contributed in planning, designing and finalization of basic idea of experiment, overall supervision during analytical work, statistical analysis of data, revision and finalization of manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Resources|Supervision|Writing - Review & Editing	YES
5517496	28775731	AK	2	contributed in overall execution of the experiment, analytical work, collection of data after biochemical analysis of seeds, organization of resulting data, write up and revision of manuscript	contributed in overall execution of the experiment, analytical work, collection of data after biochemical analysis of seeds, organization of resulting data, write up and revision of manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5387225	28400851	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5387225	28400851	DR	2	participated in the design of the study and helped to draft the manuscript|conceived and oversaw the study and helped to draft the manuscript	participated in the design of the study and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5387225	28400851	DR	2	participated in the design of the study and helped to draft the manuscript|conceived and oversaw the study and helped to draft the manuscript	conceived and oversaw the study and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Supervision|Writing - Original Draft	YES
5387225	28400851	JC	2	participated in the design of the study and took responsibility for writing the manuscript	participated in the design of the study and took responsibility for writing the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5387225	28400851	VT	2	carried out the statistical analysis and helped to draft the manuscript	carried out the statistical analysis and helped to draft the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5597112	28975920	Rex O. Brown	2	conceptualized the idea and outline for this manuscript|revised the third draft into a manuscript for submission	conceptualized the idea and outline for this manuscript	Conceived and designed the experiments	Conceptualization	YES
5597112	28975920	Rex O. Brown	2	conceptualized the idea and outline for this manuscript|revised the third draft into a manuscript for submission	revised the third draft into a manuscript for submission	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5597112	28975920	Stephan Foster	2	submitted the material that addressed the ippe program at our institution|also reviewed all three drafts and the revision for manuscript submission	submitted the material that addressed the ippe program at our institution	-	-	NO
5597112	28975920	Stephan Foster	2	submitted the material that addressed the ippe program at our institution|also reviewed all three drafts and the revision for manuscript submission	also reviewed all three drafts and the revision for manuscript submission	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5597112	28975920	Zalak Patel	2	wrote the first, second, and third drafts of this publication	wrote the first, second, and third drafts of this publication	Wrote the paper	Writing - Original Draft	YES
5241963	28100189	AJM	2	contributed to the genetic analysis|drafted the manuscript	contributed to the genetic analysis	Performed the experiments	Investigation	YES
5241963	28100189	AJM	2	contributed to the genetic analysis|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5241963	28100189	BP	2	designed the study|developed the rils population|phenotyped the ril population|drafted the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5241963	28100189	BP	2	designed the study|developed the rils population|phenotyped the ril population|drafted the manuscript	developed the rils population	-	-	NO
5241963	28100189	BP	2	designed the study|developed the rils population|phenotyped the ril population|drafted the manuscript	phenotyped the ril population	Performed the experiments	Investigation	YES
5241963	28100189	BP	2	designed the study|developed the rils population|phenotyped the ril population|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5241963	28100189	CE	2	developed the rils population|drafted the manuscript	developed the rils population	-	-	NO
5241963	28100189	CE	2	developed the rils population|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5241963	28100189	EM	2	developed the rils population|phenotyped the ril population	developed the rils population	-	-	NO
5241963	28100189	EM	2	developed the rils population|phenotyped the ril population	phenotyped the ril population	Performed the experiments	Investigation	YES
5241963	28100189	JB	2	designed the study|performed the bioinformatic analysis	designed the study	Conceived and designed the experiments	Methodology	YES
5241963	28100189	JB	2	designed the study|performed the bioinformatic analysis	performed the bioinformatic analysis	Performed the experiments	Formal analysis|Investigation	YES
5241963	28100189	JC	2	designed the study|performed the bioinformatic analysis|drafted the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5241963	28100189	JC	2	designed the study|performed the bioinformatic analysis|drafted the manuscript	performed the bioinformatic analysis	Performed the experiments	Formal analysis|Investigation	YES
5241963	28100189	JC	2	designed the study|performed the bioinformatic analysis|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5241963	28100189	JMP	2	performed the bioinformatic analysis|drafted the manuscript	performed the bioinformatic analysis	Performed the experiments	Formal analysis|Investigation	YES
5241963	28100189	JMP	2	performed the bioinformatic analysis|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5241963	28100189	PG	2	developed the rils population	developed the rils population	-	-	NO
5385319	28155207	Both authors	2	met and discussed the ideas and concept and jointly redrafted the manuscript for submission|read and approved the final manuscript	met and discussed the ideas and concept and jointly redrafted the manuscript for submission	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5385319	28155207	Both authors	2	met and discussed the ideas and concept and jointly redrafted the manuscript for submission|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5385319	28155207	JS	2	conceived the idea for the paper and wrote a preliminary draft	conceived the idea for the paper and wrote a preliminary draft	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4636859	26546789	EAF	2	conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4636859	26546789	FMH	2	conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4636859	26546789	HJW	2	designed the study materials, conducted the interviews and acquired the data|analyzed and interpreted the data|wrote the first draft of the manuscript	designed the study materials, conducted the interviews and acquired the data	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4636859	26546789	HJW	2	designed the study materials, conducted the interviews and acquired the data|analyzed and interpreted the data|wrote the first draft of the manuscript	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
4636859	26546789	HJW	2	designed the study materials, conducted the interviews and acquired the data|analyzed and interpreted the data|wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
4636859	26546789	IC	2	designed the study materials, conducted the interviews and acquired the data	designed the study materials, conducted the interviews and acquired the data	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4636859	26546789	KP	2	conceived the study|designed the study materials, conducted the interviews and acquired the data|analyzed and interpreted the data|contributed to significant revisions of the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4636859	26546789	KP	2	conceived the study|designed the study materials, conducted the interviews and acquired the data|analyzed and interpreted the data|contributed to significant revisions of the manuscript	designed the study materials, conducted the interviews and acquired the data	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4636859	26546789	KP	2	conceived the study|designed the study materials, conducted the interviews and acquired the data|analyzed and interpreted the data|contributed to significant revisions of the manuscript	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
4636859	26546789	KP	2	conceived the study|designed the study materials, conducted the interviews and acquired the data|analyzed and interpreted the data|contributed to significant revisions of the manuscript	contributed to significant revisions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4636859	26546789	LLH	2	designed the study materials, conducted the interviews and acquired the data|analyzed and interpreted the data	designed the study materials, conducted the interviews and acquired the data	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4636859	26546789	LLH	2	designed the study materials, conducted the interviews and acquired the data|analyzed and interpreted the data	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
4636859	26546789	SDW	2	conceived the study|designed the study materials, conducted the interviews and acquired the data|analyzed and interpreted the data|contributed to significant revisions of the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4636859	26546789	SDW	2	conceived the study|designed the study materials, conducted the interviews and acquired the data|analyzed and interpreted the data|contributed to significant revisions of the manuscript	designed the study materials, conducted the interviews and acquired the data	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4636859	26546789	SDW	2	conceived the study|designed the study materials, conducted the interviews and acquired the data|analyzed and interpreted the data|contributed to significant revisions of the manuscript	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
4636859	26546789	SDW	2	conceived the study|designed the study materials, conducted the interviews and acquired the data|analyzed and interpreted the data|contributed to significant revisions of the manuscript	contributed to significant revisions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4636859	26546789	TN	2	designed the study materials, conducted the interviews and acquired the data|analyzed and interpreted the data	designed the study materials, conducted the interviews and acquired the data	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4636859	26546789	TN	2	designed the study materials, conducted the interviews and acquired the data|analyzed and interpreted the data	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
4636859	26546789	all other authors	2	were involved in subsequent critical revisions	were involved in subsequent critical revisions	Wrote the paper	Writing - Review & Editing	YES
4404353	25894572	BWJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404353	25894572	BWJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404353	25894572	BWJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404353	25894572	BWJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404353	25894572	BWJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404353	25894572	HY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404353	25894572	HY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404353	25894572	HY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404353	25894572	HY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404353	25894572	HY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404353	25894572	JEL	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404353	25894572	JEL	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4404353	25894572	JEL	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404353	25894572	KK	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404353	25894572	KK	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4404353	25894572	KK	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404353	25894572	SJK	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404353	25894572	SJK	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4404353	25894572	SJK	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4917488	27358730	Abubakar Shafiq	7	Literature review, Data acquisition, Preparation of manuscript	Literature review, Data acquisition, Preparation of manuscript	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
4917488	27358730	Awais Amjad Malik	7	Guarantor	Guarantor	-	-	NO
4917488	27358730	Huma Sabir Khan	7	Data analysis, Preparation of final Manuscript	Data analysis, Preparation of final Manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
4917488	27358730	Mahmood Ayyaz	7	Preparation of Final Manuscript	Preparation of Final Manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4917488	27358730	Muhammad Kashif	7	Data analysis, Preparation of final Manuscript	Data analysis, Preparation of final Manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
4917488	27358730	Romaisa Shamim	7	Literature review, Data acquisition, Preparation of manuscript	Literature review, Data acquisition, Preparation of manuscript	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
4917488	27358730	Samiullah Bhatti	7	principal investigator	principal investigator	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
4917488	27358730	Syed Muhammad Bilal	7	Literature review, Data analysis	Literature review, Data analysis	Analyzed the data	Formal analysis	YES
4917488	27358730	Usman Ismat Butt	7	Literature review, Data analysis	Literature review, Data analysis	Analyzed the data	Formal analysis	YES
5517502	28775729	AX	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5517502	28775729	CY	PLoS5	Conceived and designed the experiments, performed the bioinformatics analysis and wrote the paper	Conceived and designed the experiments, performed the bioinformatics analysis and wrote the paper	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5517502	28775729	JD	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
5517502	28775729	JD	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5517502	28775729	SH	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5517502	28775729	XL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5517502	28775729	ZL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5898025	29397368	AM	PLoS52	organized the project and provided comments	organized the project and provided comments	-	Project administration	YES
5898025	29397368	BS	PLoS52	organized the project and provided comments	organized the project and provided comments	-	Project administration	YES
5898025	29397368	HH	PLoS52	contributed to the table 2 and provided comments	contributed to the table 2 and provided comments	-	-	NO
5898025	29397368	ID	PLoS52	provided essential comments	provided essential comments	-	-	NO
5898025	29397368	MA	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5898025	29397368	WM	PLoS52	conceptualized and designed the study, contributed to data analyzing, and wrote the manuscript	conceptualized and designed the study, contributed to data analyzing, and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
4637348	26548767	HMP	2	has read and approved the final manuscript	has read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4637348	26548767	JLZ	2	was the principal author of the manuscript	was the principal author of the manuscript	Wrote the paper	Writing - Original Draft	YES
5389951	28168631	AR	2	designed the study and wrote the protocol	designed the study and wrote the protocol	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5389951	28168631	All authors	2	contributed to and have approved the final manuscript|read and approved the final manuscript	contributed to and have approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5389951	28168631	All authors	2	contributed to and have approved the final manuscript|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5389951	28168631	JD	2	designed the study and wrote the protocol	designed the study and wrote the protocol	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5389951	28168631	JK	2	assisted by the statistical analysis was blinded to conduct the interviews in the post-measurement	assisted by the statistical analysis was blinded to conduct the interviews in the post-measurement	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5389951	28168631	JV	2	designed the study and wrote the protocol|conducted the neurocognitive testing|did the literature searches, the analyses and wrote the first draft of the manuscript	designed the study and wrote the protocol	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5389951	28168631	JV	2	designed the study and wrote the protocol|conducted the neurocognitive testing|did the literature searches, the analyses and wrote the first draft of the manuscript	conducted the neurocognitive testing	Performed the experiments	Investigation	YES
5389951	28168631	JV	2	designed the study and wrote the protocol|conducted the neurocognitive testing|did the literature searches, the analyses and wrote the first draft of the manuscript	did the literature searches, the analyses and wrote the first draft of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5389951	28168631	SK	2	helped in recruitment of patients	helped in recruitment of patients	Performed the experiments	Investigation	YES
5387298	28400850	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5387298	28400850	DB	2	were involved in acquisition of data and critical revision of the manuscript for important intellectual content	were involved in acquisition of data and critical revision of the manuscript for important intellectual content	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5387298	28400850	DP	2	was involved in the conception and design of the study and critical revision of the manuscript for important intellectual content	was involved in the conception and design of the study and critical revision of the manuscript for important intellectual content	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
5387298	28400850	EP	2	were involved in acquisition of data and critical revision of the manuscript for important intellectual content	were involved in acquisition of data and critical revision of the manuscript for important intellectual content	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5387298	28400850	FY	2	were involved in critical revision of the manuscript for important intellectual content	were involved in critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5387298	28400850	HC	2	made substantial contributions to the conception and design of the study and acquisition of data and provided important intellectual content	made substantial contributions to the conception and design of the study and acquisition of data and provided important intellectual content	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceptualization|Investigation|Methodology|Resources	YES
5387298	28400850	KM	2	were involved in acquisition of data and critical revision of the manuscript for important intellectual content	were involved in acquisition of data and critical revision of the manuscript for important intellectual content	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5387298	28400850	LD	2	were involved in acquisition of data and critical revision of the manuscript for important intellectual content	were involved in acquisition of data and critical revision of the manuscript for important intellectual content	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5387298	28400850	LG	2	conducted the statistical analyses and drafted sections of the manuscript	conducted the statistical analyses and drafted sections of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5387298	28400850	LM	2	were involved in critical revision of the manuscript for important intellectual content	were involved in critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5387298	28400850	MK	2	were involved in acquisition of data and critical revision of the manuscript for important intellectual content	were involved in acquisition of data and critical revision of the manuscript for important intellectual content	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5387298	28400850	MM	2	were involved in acquisition of data and critical revision of the manuscript for important intellectual content	were involved in acquisition of data and critical revision of the manuscript for important intellectual content	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5387298	28400850	PC	2	made substantial contributions to the conception and design of the study and drafted sections of the manuscript	made substantial contributions to the conception and design of the study and drafted sections of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
5387298	28400850	RF	2	conducted all the qualitative analyses and made substantial contributions to the conception and design of the study and acquisition of data	conducted all the qualitative analyses and made substantial contributions to the conception and design of the study and acquisition of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Methodology|Resources	YES
5387298	28400850	TE	2	were involved in critical revision of the manuscript for important intellectual content	were involved in critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5387298	28400850	WM	2	were involved in acquisition of data and critical revision of the manuscript for important intellectual content	were involved in acquisition of data and critical revision of the manuscript for important intellectual content	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4919797	27366322	Gulshan Bano	2	performed statistical analysis	performed statistical analysis	Analyzed the data	Formal analysis	YES
4919797	27366322	Jamal Khan	2	did manuscript writing	did manuscript writing	Wrote the paper	Writing - Original Draft	YES
4919797	27366322	Sheema Khan	2	did manuscript writing	did manuscript writing	Wrote the paper	Writing - Original Draft	YES
4919797	27366322	Shiraz Hashmi	2	performed statistical analysis	performed statistical analysis	Analyzed the data	Formal analysis	YES
4404354	25894430	KO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404354	25894430	KO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404354	25894430	KO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404354	25894430	KO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404354	25894430	MA	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404354	25894430	MA	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404354	25894430	MA	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404354	25894430	ME	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404354	25894430	ME	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404354	25894430	ME	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404354	25894430	MI	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404354	25894430	MI	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404354	25894430	MI	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404354	25894430	PMZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404354	25894430	PMZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404354	25894430	PMZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404354	25894430	SK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404354	25894430	SK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404354	25894430	SK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404354	25894430	WS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404354	25894430	WS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404354	25894430	WS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404354	25894430	YT	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404354	25894430	YT	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404354	25894430	YT	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4925906	27408712	Hye Jin Baek	7	data collection and analysis, radiologic investigations, literature review, refinement of manuscript, review of final manuscript	data collection and analysis, radiologic investigations, literature review, refinement of manuscript, review of final manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
4925906	27408712	Kwang Ho Choi	7	data design, data collection, literature review, manuscript writing and revision, review of final manuscript. 2	data design, data collection, literature review, manuscript writing and revision, review of final manuscript. 2	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5925575	29452862	AG	PLoS5	Contributed to study design|Contributed to data analysis|Wrote the paper	Contributed to study design	Conceived and designed the experiments	Methodology	YES
5925575	29452862	AG	PLoS5	Contributed to study design|Contributed to data analysis|Wrote the paper	Contributed to data analysis	Analyzed the data	Formal analysis	YES
5925575	29452862	AG	PLoS5	Contributed to study design|Contributed to data analysis|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5925575	29452862	APG	PLoS5	Contributed to study design|Contributed to data analysis|Wrote the paper	Contributed to study design	Conceived and designed the experiments	Methodology	YES
5925575	29452862	APG	PLoS5	Contributed to study design|Contributed to data analysis|Wrote the paper	Contributed to data analysis	Analyzed the data	Formal analysis	YES
5925575	29452862	APG	PLoS5	Contributed to study design|Contributed to data analysis|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5925575	29452862	All	PLoS5	Contributed to editing the paper	Contributed to editing the paper	Wrote the paper	Writing - Review & Editing	YES
5925575	29452862	BEE	PLoS5	Contributed to data analysis	Contributed to data analysis	Analyzed the data	Formal analysis	YES
5925575	29452862	LMJ	PLoS5	Contributed to data analysis|Wrote the paper	Contributed to data analysis	Analyzed the data	Formal analysis	YES
5925575	29452862	LMJ	PLoS5	Contributed to data analysis|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5925575	29452862	PC	PLoS5	Contributed to data collection|Contributed to data analysis	Contributed to data collection	Performed the experiments	Investigation	YES
5925575	29452862	PC	PLoS5	Contributed to data collection|Contributed to data analysis	Contributed to data analysis	Analyzed the data	Formal analysis	YES
5925575	29452862	SML	PLoS5	Contributed to data collection	Contributed to data collection	Performed the experiments	Investigation	YES
5241972	28100185	AJN	2	performed the genome assemblies|wrote the paper with	performed the genome assemblies	Performed the experiments	Investigation	YES
5241972	28100185	AJN	2	performed the genome assemblies|wrote the paper with	wrote the paper with	Wrote the paper	Writing - Original Draft	YES
5241972	28100185	AT-K	2	performed library creation and sequencing	performed library creation and sequencing	Performed the experiments	Investigation	YES
5241972	28100185	BPW	2	designed and wrote the assembly algorithms|wrote the paper with	designed and wrote the assembly algorithms	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Software|Writing - Original Draft	YES
5241972	28100185	BPW	2	designed and wrote the assembly algorithms|wrote the paper with	wrote the paper with	Wrote the paper	Writing - Original Draft	YES
5241972	28100185	BS	2	wrote the paper with	wrote the paper with	Wrote the paper	Writing - Original Draft	YES
5241972	28100185	HG	2	created the linkage map	created the linkage map	-	-	NO
5241972	28100185	JK	2	designed and wrote the assembly algorithms	designed and wrote the assembly algorithms	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Software|Writing - Original Draft	YES
5241972	28100185	JME	2	performed library creation and sequencing	performed library creation and sequencing	Performed the experiments	Investigation	YES
5241972	28100185	JRM	2	designed and wrote the assembly algorithms	designed and wrote the assembly algorithms	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Software|Writing - Original Draft	YES
5241972	28100185	KSJ	2	wrote the paper with	wrote the paper with	Wrote the paper	Writing - Original Draft	YES
5241972	28100185	MS	2	performed library creation and sequencing	performed library creation and sequencing	Performed the experiments	Investigation	YES
5241972	28100185	OKT	2	performed the genome assemblies|annotated the genome assembly|carried out the tr analysis|wrote the paper with	performed the genome assemblies	Performed the experiments	Investigation	YES
5241972	28100185	OKT	2	performed the genome assemblies|annotated the genome assembly|carried out the tr analysis|wrote the paper with	annotated the genome assembly	-	-	NO
5241972	28100185	OKT	2	performed the genome assemblies|annotated the genome assembly|carried out the tr analysis|wrote the paper with	carried out the tr analysis	Performed the experiments	Investigation	YES
5241972	28100185	OKT	2	performed the genome assemblies|annotated the genome assembly|carried out the tr analysis|wrote the paper with	wrote the paper with	Wrote the paper	Writing - Original Draft	YES
5241972	28100185	PP	2	performed library creation and sequencing	performed library creation and sequencing	Performed the experiments	Investigation	YES
5241972	28100185	RBE	2	contributed samples for sequencing and evaluated assemblies	contributed samples for sequencing and evaluated assemblies	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5241972	28100185	SJ	2	wrote the paper with	wrote the paper with	Wrote the paper	Writing - Original Draft	YES
5241972	28100185	SL	2	created the linkage map	created the linkage map	-	-	NO
5241972	28100185	WBR	2	annotated the genome assembly	annotated the genome assembly	-	-	NO
5241972	28100185	all the authors	2	helped with the wrote the paper with	helped with the wrote the paper with	Wrote the paper	Writing - Original Draft	YES
4641978	26561337	GMG	2	contributed equally to the preparation of the manuscript	contributed equally to the preparation of the manuscript	Wrote the paper	Writing - Original Draft	YES
4641978	26561337	JBA	2	contributed equally to the preparation of the manuscript	contributed equally to the preparation of the manuscript	Wrote the paper	Writing - Original Draft	YES
5406320	28332123	AL	2	have each made substantial contributions to the conception and design, or acquisition of data, or analysis and interpretation of data, have been involved in drafting the manuscript or revising it critically for important intellectual content, and have given final approval of the manuscript	have each made substantial contributions to the conception and design, or acquisition of data, or analysis and interpretation of data, have been involved in drafting the manuscript or revising it critically for important intellectual content, and have given final approval of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5406320	28332123	AS	2	have each made substantial contributions to the conception and design, or acquisition of data, or analysis and interpretation of data, have been involved in drafting the manuscript or revising it critically for important intellectual content, and have given final approval of the manuscript	have each made substantial contributions to the conception and design, or acquisition of data, or analysis and interpretation of data, have been involved in drafting the manuscript or revising it critically for important intellectual content, and have given final approval of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5406320	28332123	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5406320	28332123	BG	2	have each made substantial contributions to the conception and design, or acquisition of data, or analysis and interpretation of data, have been involved in drafting the manuscript or revising it critically for important intellectual content, and have given final approval of the manuscript	have each made substantial contributions to the conception and design, or acquisition of data, or analysis and interpretation of data, have been involved in drafting the manuscript or revising it critically for important intellectual content, and have given final approval of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5406320	28332123	CR	2	have each made substantial contributions to the conception and design, or acquisition of data, or analysis and interpretation of data, have been involved in drafting the manuscript or revising it critically for important intellectual content, and have given final approval of the manuscript	have each made substantial contributions to the conception and design, or acquisition of data, or analysis and interpretation of data, have been involved in drafting the manuscript or revising it critically for important intellectual content, and have given final approval of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5406320	28332123	LW	2	have each made substantial contributions to the conception and design, or acquisition of data, or analysis and interpretation of data, have been involved in drafting the manuscript or revising it critically for important intellectual content, and have given final approval of the manuscript	have each made substantial contributions to the conception and design, or acquisition of data, or analysis and interpretation of data, have been involved in drafting the manuscript or revising it critically for important intellectual content, and have given final approval of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5406320	28332123	LY	2	have each made substantial contributions to the conception and design, or acquisition of data, or analysis and interpretation of data, have been involved in drafting the manuscript or revising it critically for important intellectual content, and have given final approval of the manuscript	have each made substantial contributions to the conception and design, or acquisition of data, or analysis and interpretation of data, have been involved in drafting the manuscript or revising it critically for important intellectual content, and have given final approval of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5406320	28332123	MS	2	have each made substantial contributions to the conception and design, or acquisition of data, or analysis and interpretation of data, have been involved in drafting the manuscript or revising it critically for important intellectual content, and have given final approval of the manuscript	have each made substantial contributions to the conception and design, or acquisition of data, or analysis and interpretation of data, have been involved in drafting the manuscript or revising it critically for important intellectual content, and have given final approval of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5517574	28775735	JH	PLoS52	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5517574	28775735	JN	PLoS52	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5517574	28775735	LW	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5517574	28775735	WBL	PLoS52	performed the histological analysis	performed the histological analysis	Performed the experiments	Investigation	YES
5517574	28775735	WLL	PLoS52	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5517574	28775735	XC	PLoS52	performed the scanning electron microscopy	performed the scanning electron microscopy	Performed the experiments	Investigation	YES
5517574	28775735	YM	PLoS52	conceived and designed the experiments|performed the histological analysis|performed the scanning electron microscopy|analyzed sequencing data	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5517574	28775735	YM	PLoS52	conceived and designed the experiments|performed the histological analysis|performed the scanning electron microscopy|analyzed sequencing data	performed the histological analysis	Performed the experiments	Investigation	YES
5517574	28775735	YM	PLoS52	conceived and designed the experiments|performed the histological analysis|performed the scanning electron microscopy|analyzed sequencing data	performed the scanning electron microscopy	Performed the experiments	Investigation	YES
5517574	28775735	YM	PLoS52	conceived and designed the experiments|performed the histological analysis|performed the scanning electron microscopy|analyzed sequencing data	analyzed sequencing data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5517574	28775735	YW	PLoS52	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5517574	28775735	YX	PLoS52	performed the scanning electron microscopy	performed the scanning electron microscopy	Performed the experiments	Investigation	YES
5401471	28431556	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5401471	28431556	FC	2	were involved in data collection	were involved in data collection	Performed the experiments	Investigation	YES
5401471	28431556	GM	2	designed the study, wrote the proposal, analyzed the data, and prepared the manuscript	designed the study, wrote the proposal, analyzed the data, and prepared the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5401471	28431556	KM	2	was involved in proposal writing, statistical analysis, and manuscript preparation	was involved in proposal writing, statistical analysis, and manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5401471	28431556	MG	2	were involved in data collection	were involved in data collection	Performed the experiments	Investigation	YES
5401471	28431556	NP	2	designed the study, wrote the proposal, analyzed the data, and prepared the manuscript|were involved in data collection	designed the study, wrote the proposal, analyzed the data, and prepared the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5401471	28431556	NP	2	designed the study, wrote the proposal, analyzed the data, and prepared the manuscript|were involved in data collection	were involved in data collection	Performed the experiments	Investigation	YES
5401471	28431556	The authors	2	declare they have no competing interests	declare they have no competing interests	-	-	NO
5597115	28975923	Collin Anderson	2	contributed to the conception and design of work|performed the analyses|contributed to the final manuscript	contributed to the conception and design of work	Conceived and designed the experiments	Conceptualization	YES
5597115	28975923	Collin Anderson	2	contributed to the conception and design of work|performed the analyses|contributed to the final manuscript	performed the analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5597115	28975923	Collin Anderson	2	contributed to the conception and design of work|performed the analyses|contributed to the final manuscript	contributed to the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5597115	28975923	Mark MacKay	2	contributed to the conception and design of work|contributed to the final manuscript	contributed to the conception and design of work	Conceived and designed the experiments	Conceptualization	YES
5597115	28975923	Mark MacKay	2	contributed to the conception and design of work|contributed to the final manuscript	contributed to the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4404355	25894980	JDD	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404355	25894980	MLW	PLoS5	Drew the figures|Revised the manuscript	Drew the figures	-	Visualization	YES
4404355	25894980	MLW	PLoS5	Drew the figures|Revised the manuscript	Revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4404355	25894980	YSW	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404355	25894980	ZWC	PLoS5	Performed the experiments|Took samples	Performed the experiments	Performed the experiments	Investigation	YES
4404355	25894980	ZWC	PLoS5	Performed the experiments|Took samples	Took samples	Performed the experiments	Investigation	YES
4404355	25894980	ZZW	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404355	25894980	ZZW	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5925578	29449195	AM	2	planned the project	planned the project	Conceived and designed the experiments	Conceptualization	YES
5925578	29449195	CP	2	provided blood from rheumatoid arthritis patients	provided blood from rheumatoid arthritis patients	Performed the experiments	Investigation	YES
5925578	29449195	FD	2	provided blood from rheumatoid arthritis patients	provided blood from rheumatoid arthritis patients	Performed the experiments	Investigation	YES
5925578	29449195	HIR	2	designed, performed and analysed experiments|wrote the manuscript	designed, performed and analysed experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5925578	29449195	HIR	2	designed, performed and analysed experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5925578	29449195	LVN	2	planned the project|designed, performed and analysed experiments	planned the project	Conceived and designed the experiments	Conceptualization	YES
5925578	29449195	LVN	2	planned the project|designed, performed and analysed experiments	designed, performed and analysed experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5925578	29449195	MP	2	planned the project|designed, performed and analysed experiments|wrote the manuscript	planned the project	Conceived and designed the experiments	Conceptualization	YES
5925578	29449195	MP	2	planned the project|designed, performed and analysed experiments|wrote the manuscript	designed, performed and analysed experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5925578	29449195	MP	2	planned the project|designed, performed and analysed experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5925578	29449195	all other authors	2	provided advice and oversight of the manuscript	provided advice and oversight of the manuscript	-	Supervision	YES
4927636	27408713	ME	7	Reviewed data and manuscript	Reviewed data and manuscript	Wrote the paper	Writing - Review & Editing	YES
4927636	27408713	MR	7	Wrote & edited Manuscript	Wrote & edited Manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4927636	27408713	RS	7	Collected all data, wrote manuscripts	Collected all data, wrote manuscripts	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5420548	28247268	All authors	2	participated equally in the conception and writing design of the review|selected and reviewed the literature and drafted the manuscript|read and approved the final manuscript	participated equally in the conception and writing design of the review	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5420548	28247268	All authors	2	participated equally in the conception and writing design of the review|selected and reviewed the literature and drafted the manuscript|read and approved the final manuscript	selected and reviewed the literature and drafted the manuscript	Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5420548	28247268	All authors	2	participated equally in the conception and writing design of the review|selected and reviewed the literature and drafted the manuscript|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5420548	28247268	The authors	2	declare that they have no competing interests|assert that all procedures contributing to this work comply with the ethical standards of the relevant national and institutional committees on human experimentation and with the helsinki declaration of 1975, as revised in 2008	declare that they have no competing interests	-	-	NO
5420548	28247268	The authors	2	declare that they have no competing interests|assert that all procedures contributing to this work comply with the ethical standards of the relevant national and institutional committees on human experimentation and with the helsinki declaration of 1975, as revised in 2008	assert that all procedures contributing to this work comply with the ethical standards of the relevant national and institutional committees on human experimentation and with the helsinki declaration of 1975, as revised in 2008	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4643166	26563846	All authors	2	contributed to the study design|read, commented on and approved the final manuscript	contributed to the study design	Conceived and designed the experiments	Methodology	YES
4643166	26563846	All authors	2	contributed to the study design|read, commented on and approved the final manuscript	read, commented on and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4643166	26563846	JA	2	provided supplemental statistical analyses	provided supplemental statistical analyses	Analyzed the data	Formal analysis	YES
4643166	26563846	TL	2	conducted the primary statistical analyses	conducted the primary statistical analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5414136	28469695	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5414136	28469695	DYG	2	participated in its design and coordination and helped to draft the manuscript	participated in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Project administration|Writing - Original Draft	YES
5414136	28469695	E Gi	2	advised on data analysis and participated in interpreting the data and reviewing the manuscript	advised on data analysis and participated in interpreting the data and reviewing the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5414136	28469695	HZ	2	devised the study, advised on data analysis and participated in interpreting the data and reviewing the manuscript	devised the study, advised on data analysis and participated in interpreting the data and reviewing the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Review & Editing	YES
5414136	28469695	LPD	2	advised on data analysis and participated in interpreting the data and reviewing the manuscript	advised on data analysis and participated in interpreting the data and reviewing the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5414136	28469695	MQL	2	advised on data analysis and participated in interpreting the data and reviewing the manuscript	advised on data analysis and participated in interpreting the data and reviewing the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5414136	28469695	RRY	2	devised the study, advised on data analysis and participated in interpreting the data and reviewing the manuscript	devised the study, advised on data analysis and participated in interpreting the data and reviewing the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Review & Editing	YES
5414136	28469695	SCG	2	advised on data analysis and participated in interpreting the data and reviewing the manuscript	advised on data analysis and participated in interpreting the data and reviewing the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5414136	28469695	WH	2	participated in its design and coordination and helped to draft the manuscript	participated in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Project administration|Writing - Original Draft	YES
5414136	28469695	YX	2	devised the study, advised on data analysis and participated in interpreting the data and reviewing the manuscript	devised the study, advised on data analysis and participated in interpreting the data and reviewing the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Review & Editing	YES
5414136	28469695	YXZ	2	advised on data analysis and participated in interpreting the data and reviewing the manuscript	advised on data analysis and participated in interpreting the data and reviewing the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5242001	28100167	All authors	2	contributed to experiment execution, handling of data and preparation of the final versions of the manuscript	contributed to experiment execution, handling of data and preparation of the final versions of the manuscript	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Resources|Writing - Original Draft	YES
5242001	28100167	DW	2	designed and supervised the study	designed and supervised the study	Conceived and designed the experiments	Methodology|Supervision	YES
5242001	28100167	HRM	2	designed and supervised the study	designed and supervised the study	Conceived and designed the experiments	Methodology|Supervision	YES
5597116	28975924	Ashley N. Castleberry	PLoS52	analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5597116	28975924	Ashley N. Castleberry	PLoS52	analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5597116	28975924	Denise Ragland	PLoS52	conceived and designed the experiments|analyzed the data|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5597116	28975924	Denise Ragland	PLoS52	conceived and designed the experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5597116	28975924	Denise Ragland	PLoS52	conceived and designed the experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5597116	28975924	Nalin Payakachat	PLoS52	conceived and designed the experiments|analyzed the data|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5597116	28975924	Nalin Payakachat	PLoS52	conceived and designed the experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5597116	28975924	Nalin Payakachat	PLoS52	conceived and designed the experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5597116	28975924	Paul O. Gubbins	PLoS52	analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5597116	28975924	Paul O. Gubbins	PLoS52	analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5518647	28775728	HE	2	performed hplc analysis for aas and phenolic compounds	performed hplc analysis for aas and phenolic compounds	Performed the experiments	Investigation	YES
5518647	28775728	KdP	2	performed rna processing and rna seq data analysis|drafted the original manuscript and all authors contributed and finalized the publication	performed rna processing and rna seq data analysis	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5518647	28775728	KdP	2	performed rna processing and rna seq data analysis|drafted the original manuscript and all authors contributed and finalized the publication	drafted the original manuscript and all authors contributed and finalized the publication	Wrote the paper	Writing - Original Draft	YES
5518647	28775728	MV	2	conceptualized and planned the study|drafted the original manuscript and all authors contributed and finalized the publication	conceptualized and planned the study	Conceived and designed the experiments	Conceptualization	YES
5518647	28775728	MV	2	conceptualized and planned the study|drafted the original manuscript and all authors contributed and finalized the publication	drafted the original manuscript and all authors contributed and finalized the publication	Wrote the paper	Writing - Original Draft	YES
5518647	28775728	PY	2	conceptualized and planned the study|implemented and maintained the viticultural treatments and was responsible for the berry sampling|drafted the original manuscript and all authors contributed and finalized the publication	conceptualized and planned the study	Conceived and designed the experiments	Conceptualization	YES
5518647	28775728	PY	2	conceptualized and planned the study|implemented and maintained the viticultural treatments and was responsible for the berry sampling|drafted the original manuscript and all authors contributed and finalized the publication	implemented and maintained the viticultural treatments and was responsible for the berry sampling	Performed the experiments	Investigation	YES
5518647	28775728	PY	2	conceptualized and planned the study|implemented and maintained the viticultural treatments and was responsible for the berry sampling|drafted the original manuscript and all authors contributed and finalized the publication	drafted the original manuscript and all authors contributed and finalized the publication	Wrote the paper	Writing - Original Draft	YES
4930340	27408714	Antonio Prestera	7	write the paper	write the paper	Wrote the paper	Writing - Original Draft	YES
4930340	27408714	Giuseppe Carbotta	7	study concept	study concept	Conceived and designed the experiments	Conceptualization	YES
4930340	27408714	Nicola Palasciano	7	supervisor	supervisor	-	Supervision	YES
4930340	27408714	Pierluca Sallustio	7	write the paper	write the paper	Wrote the paper	Writing - Original Draft	YES
4930340	27408714	Pierluigi Lobascio	7	rewied of literature	rewied of literature	-	-	NO
4930340	27408714	Rita Laforgia	7	English translate	English translate	-	-	NO
4404356	25893241	AWD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404356	25893241	AWD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404356	25893241	AWD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404356	25893241	AWD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404356	25893241	JT	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404356	25893241	JWD	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404356	25893241	LC	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404356	25893241	LC	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404356	25893241	MMK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404356	25893241	MMK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404356	25893241	MMK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404356	25893241	MMK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5597141	28970428	All authors	2	contributed to development of the concept and prepared the manuscript	contributed to development of the concept and prepared the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5597141	28970428	Beverley D. Glass	2	provided tertiary health education expertise	provided tertiary health education expertise	-	-	NO
5597141	28970428	Martina F. Mylrea	2	wrote the paper and all authors critically revised, contributed with comments, and approved the final version of the manuscript	wrote the paper and all authors critically revised, contributed with comments, and approved the final version of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5925620	29500127	AWH	2	designed the study|analysed the results and wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5925620	29500127	AWH	2	designed the study|analysed the results and wrote the manuscript	analysed the results and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5925620	29500127	CO	2	performed the experimental work	performed the experimental work	Performed the experiments	Investigation	YES
5925620	29500127	GE	2	contributed to experimental design and critical feedback on manuscript	contributed to experimental design and critical feedback on manuscript	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5925620	29500127	GSW	2	performed the experimental work	performed the experimental work	Performed the experiments	Investigation	YES
5925620	29500127	HODC	2	designed the study|contributed to experimental design and critical feedback on manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5925620	29500127	HODC	2	designed the study|contributed to experimental design and critical feedback on manuscript	contributed to experimental design and critical feedback on manuscript	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5925620	29500127	JKB	2	performed the experimental work|analysed the results and wrote the manuscript	performed the experimental work	Performed the experiments	Investigation	YES
5925620	29500127	JKB	2	performed the experimental work|analysed the results and wrote the manuscript	analysed the results and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5925620	29500127	KFL	2	contributed to experimental design and critical feedback on manuscript	contributed to experimental design and critical feedback on manuscript	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5925620	29500127	LLC	2	analysed the results and wrote the manuscript	analysed the results and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5925620	29500127	MK	2	performed the experimental work	performed the experimental work	Performed the experiments	Investigation	YES
5925620	29500127	MOM	2	performed the experimental work	performed the experimental work	Performed the experiments	Investigation	YES
5925620	29500127	NW	2	performed the experimental work|contributed to experimental design and critical feedback on manuscript	performed the experimental work	Performed the experiments	Investigation	YES
5925620	29500127	NW	2	performed the experimental work|contributed to experimental design and critical feedback on manuscript	contributed to experimental design and critical feedback on manuscript	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5925620	29500127	PJH	2	contributed to experimental design and critical feedback on manuscript	contributed to experimental design and critical feedback on manuscript	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5925620	29500127	SFA	2	performed the experimental work|analysed the results and wrote the manuscript	performed the experimental work	Performed the experiments	Investigation	YES
5925620	29500127	SFA	2	performed the experimental work|analysed the results and wrote the manuscript	analysed the results and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5925620	29500127	SG	2	performed the experimental work	performed the experimental work	Performed the experiments	Investigation	YES
5925620	29500127	SMcF	2	performed the experimental work	performed the experimental work	Performed the experiments	Investigation	YES
5925620	29500127	WCD	2	contributed to experimental design and critical feedback on manuscript	contributed to experimental design and critical feedback on manuscript	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5414162	28469696	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5414162	28469696	KM	2	participated in the design of the study, drafting of the manuscript, and table/figure design|performed analysis of data	participated in the design of the study, drafting of the manuscript, and table/figure design	Conceived and designed the experiments|Wrote the paper	Methodology|Visualization|Writing - Original Draft	YES
5414162	28469696	KM	2	participated in the design of the study, drafting of the manuscript, and table/figure design|performed analysis of data	performed analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5414162	28469696	PL	2	participated in the design of the study, drafting of the manuscript, and table/figure design|performed analysis of data	participated in the design of the study, drafting of the manuscript, and table/figure design	Conceived and designed the experiments|Wrote the paper	Methodology|Visualization|Writing - Original Draft	YES
5414162	28469696	PL	2	participated in the design of the study, drafting of the manuscript, and table/figure design|performed analysis of data	performed analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5414162	28469696	RD	2	participated in the design of the study, drafting of the manuscript, and table/figure design|further contributed with statistical analysis	participated in the design of the study, drafting of the manuscript, and table/figure design	Conceived and designed the experiments|Wrote the paper	Methodology|Visualization|Writing - Original Draft	YES
5414162	28469696	RD	2	participated in the design of the study, drafting of the manuscript, and table/figure design|further contributed with statistical analysis	further contributed with statistical analysis	Analyzed the data	Formal analysis	YES
5414162	28469696	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
4644771	26568056	HIV	2	working group, and all authors contributed collaboratively to the development of this research and drafted, read and approved the final manuscript	working group, and all authors contributed collaboratively to the development of this research and drafted, read and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5519564	28785270	CB	2	designed the study, performed data analysis and wrote the manuscript	designed the study, performed data analysis and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5519564	28785270	GA	2	designed the study, performed data analysis, wrote the manuscript, acquired the funding, and collected the remote sensing data	designed the study, performed data analysis, wrote the manuscript, acquired the funding, and collected the remote sensing data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Funding acquisition|Investigation|Methodology|Writing - Original Draft	YES
5242011	28100169	AB	2	performed bioinformatics analyses	performed bioinformatics analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5242011	28100169	AM	2	contributed to the development of the methodology	contributed to the development of the methodology	Performed the experiments	Methodology	YES
5242011	28100169	All authors	2	wrote and approved the manuscript	wrote and approved the manuscript	Wrote the paper	Writing - Original Draft	YES
5242011	28100169	CE	2	designed the study and implemented the methodology|contributed to the development of the methodology	designed the study and implemented the methodology	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5242011	28100169	CE	2	designed the study and implemented the methodology|contributed to the development of the methodology	contributed to the development of the methodology	Performed the experiments	Methodology	YES
5242011	28100169	ESG	2	performed bisulfite and oxidative bisulfite sequencing analyses	performed bisulfite and oxidative bisulfite sequencing analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5242011	28100169	GB	2	contributed to the development of the methodology	contributed to the development of the methodology	Performed the experiments	Methodology	YES
5242011	28100169	GGC	2	contributed equally to this work|designed the study and implemented the methodology|performed bisulfite and oxidative bisulfite sequencing analyses|contributed to the development of the methodology	contributed equally to this work	-	-	NO
5242011	28100169	GGC	2	contributed equally to this work|designed the study and implemented the methodology|performed bisulfite and oxidative bisulfite sequencing analyses|contributed to the development of the methodology	designed the study and implemented the methodology	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5242011	28100169	GGC	2	contributed equally to this work|designed the study and implemented the methodology|performed bisulfite and oxidative bisulfite sequencing analyses|contributed to the development of the methodology	performed bisulfite and oxidative bisulfite sequencing analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5242011	28100169	GGC	2	contributed equally to this work|designed the study and implemented the methodology|performed bisulfite and oxidative bisulfite sequencing analyses|contributed to the development of the methodology	contributed to the development of the methodology	Performed the experiments	Methodology	YES
5242011	28100169	GM	2	performed bisulfite and oxidative bisulfite sequencing analyses	performed bisulfite and oxidative bisulfite sequencing analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5242011	28100169	GT	2	contributed to the development of the methodology	contributed to the development of the methodology	Performed the experiments	Methodology	YES
5242011	28100169	JAG	2	contributed equally to this work|designed the study and implemented the methodology|contributed to the development of the methodology	contributed equally to this work	-	-	NO
5242011	28100169	JAG	2	contributed equally to this work|designed the study and implemented the methodology|contributed to the development of the methodology	designed the study and implemented the methodology	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5242011	28100169	JAG	2	contributed equally to this work|designed the study and implemented the methodology|contributed to the development of the methodology	contributed to the development of the methodology	Performed the experiments	Methodology	YES
5242011	28100169	JFT	2	performed bioinformatics analyses	performed bioinformatics analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5242011	28100169	JG	2	performed bisulfite and oxidative bisulfite sequencing analyses	performed bisulfite and oxidative bisulfite sequencing analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5242011	28100169	KV	2	performed bisulfite and oxidative bisulfite sequencing analyses	performed bisulfite and oxidative bisulfite sequencing analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5242011	28100169	NM	2	contributed to the development of the methodology	contributed to the development of the methodology	Performed the experiments	Methodology	YES
5242011	28100169	PEL	2	contributed equally to this work|designed the study and implemented the methodology|performed bisulfite and oxidative bisulfite sequencing analyses|contributed to the development of the methodology	contributed equally to this work	-	-	NO
5242011	28100169	PEL	2	contributed equally to this work|designed the study and implemented the methodology|performed bisulfite and oxidative bisulfite sequencing analyses|contributed to the development of the methodology	designed the study and implemented the methodology	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5242011	28100169	PEL	2	contributed equally to this work|designed the study and implemented the methodology|performed bisulfite and oxidative bisulfite sequencing analyses|contributed to the development of the methodology	performed bisulfite and oxidative bisulfite sequencing analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5242011	28100169	PEL	2	contributed equally to this work|designed the study and implemented the methodology|performed bisulfite and oxidative bisulfite sequencing analyses|contributed to the development of the methodology	contributed to the development of the methodology	Performed the experiments	Methodology	YES
5242011	28100169	PL	2	contributed to the development of the methodology	contributed to the development of the methodology	Performed the experiments	Methodology	YES
5242011	28100169	UE	2	performed bisulfite and oxidative bisulfite sequencing analyses	performed bisulfite and oxidative bisulfite sequencing analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4932873	27408715	Erdem Sari	7	Participated in data collection	Participated in data collection	Performed the experiments	Investigation	YES
4932873	27408715	Kemal Erdinc Kamer	7	Participated in study design	Participated in study design	Conceived and designed the experiments	Methodology	YES
4932873	27408715	Onder Karahalli	7	Participated in data collection	Participated in data collection	Performed the experiments	Investigation	YES
4932873	27408715	Orhan Ureyen	7	Participated in data collection	Participated in data collection	Performed the experiments	Investigation	YES
4932873	27408715	Turan Acar	7	Performed the statistical analysis	Performed the statistical analysis	Analyzed the data	Formal analysis	YES
4932873	27408715	Yeliz Yilmaz	7	Designed the study, work the manuscript	Designed the study, work the manuscript	Conceived and designed the experiments	Methodology	YES
4404357	25893405	A. Angwin	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4404357	25893405	A. Auwun	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4404357	25893405	CP	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404357	25893405	EA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404357	25893405	EA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404357	25893405	EA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404357	25893405	EA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404357	25893405	EA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404357	25893405	JD	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4404357	25893405	RP	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4649013	26578252	BD	2	contributed to analyses and writing of the manuscript	contributed to analyses and writing of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4649013	26578252	DPW	2	oversaw the study and contributed to its structure and the writing of the manuscript	oversaw the study and contributed to its structure and the writing of the manuscript	Wrote the paper	Supervision|Writing - Original Draft	YES
4649013	26578252	DW	2	advised on the source and interpretation of data and interpretation of results	advised on the source and interpretation of data and interpretation of results	Analyzed the data	Formal analysis	YES
4649013	26578252	EL	2	sourced primary data on expenditure and budgets for the analyses	sourced primary data on expenditure and budgets for the analyses	Analyzed the data	Formal analysis	YES
4649013	26578252	RMS	2	led the writing of the manuscript, checking of data and production of figures	led the writing of the manuscript, checking of data and production of figures	Wrote the paper	Data curation|Visualization|Writing - Original Draft	YES
5925622	29503225	CF	CRediT	Methodology	Methodology	Performed the experiments	Methodology	YES
5925622	29503225	CR	CRediT	Resources	Resources	Contributed reagents/materials/analysis tools	Resources	YES
5925622	29503225	EM	CRediT	Analysis|Methodology	Analysis	-	-	NO
5925622	29503225	EM	CRediT	Analysis|Methodology	Methodology	Performed the experiments	Methodology	YES
5925622	29503225	GF	CRediT	Conceptualization|Investigation|Analysis|Methodology|Writing - review & editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
5925622	29503225	GF	CRediT	Conceptualization|Investigation|Analysis|Methodology|Writing - review & editing	Investigation	Performed the experiments	Investigation	YES
5925622	29503225	GF	CRediT	Conceptualization|Investigation|Analysis|Methodology|Writing - review & editing	Analysis	-	-	NO
5925622	29503225	GF	CRediT	Conceptualization|Investigation|Analysis|Methodology|Writing - review & editing	Methodology	Performed the experiments	Methodology	YES
5925622	29503225	GF	CRediT	Conceptualization|Investigation|Analysis|Methodology|Writing - review & editing	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
5925622	29503225	IL	CRediT	Resources	Resources	Contributed reagents/materials/analysis tools	Resources	YES
5925622	29503225	IS	CRediT	Conceptualization|Resources|Writing - review & editing|Funding acquisition	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
5925622	29503225	IS	CRediT	Conceptualization|Resources|Writing - review & editing|Funding acquisition	Resources	Contributed reagents/materials/analysis tools	Resources	YES
5925622	29503225	IS	CRediT	Conceptualization|Resources|Writing - review & editing|Funding acquisition	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
5925622	29503225	IS	CRediT	Conceptualization|Resources|Writing - review & editing|Funding acquisition	Funding acquisition	-	Funding acquisition	YES
5925622	29503225	JV	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
5925622	29503225	MQ	CRediT	Analysis	Analysis	-	-	NO
5925622	29503225	NR	CRediT	Writing - review & editing	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
5925622	29503225	PM	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
5925622	29503225	PP	CRediT	Analysis	Analysis	-	-	NO
5925622	29503225	SG	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
5519573	28785274	JR	PLoS5	Analyzed the data|Wrote the paper|Implemented reviewers comments	Analyzed the data	Analyzed the data	Formal analysis	YES
5519573	28785274	JR	PLoS5	Analyzed the data|Wrote the paper|Implemented reviewers comments	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5519573	28785274	JR	PLoS5	Analyzed the data|Wrote the paper|Implemented reviewers comments	Implemented reviewers comments	Performed the experiments	Investigation	YES
5519573	28785274	LA-O	PLoS5	Conceived and designed the experiments|Performed the evaluations|Analyzed the data|Wrote the paper|Implemented reviewers comments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5519573	28785274	LA-O	PLoS5	Conceived and designed the experiments|Performed the evaluations|Analyzed the data|Wrote the paper|Implemented reviewers comments	Performed the evaluations	Performed the experiments	Investigation	YES
5519573	28785274	LA-O	PLoS5	Conceived and designed the experiments|Performed the evaluations|Analyzed the data|Wrote the paper|Implemented reviewers comments	Analyzed the data	Analyzed the data	Formal analysis	YES
5519573	28785274	LA-O	PLoS5	Conceived and designed the experiments|Performed the evaluations|Analyzed the data|Wrote the paper|Implemented reviewers comments	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5519573	28785274	LA-O	PLoS5	Conceived and designed the experiments|Performed the evaluations|Analyzed the data|Wrote the paper|Implemented reviewers comments	Implemented reviewers comments	Performed the experiments	Investigation	YES
5519573	28785274	PS	PLoS5	Analyzed the data|Wrote the paper|Implemented reviewers comments	Analyzed the data	Analyzed the data	Formal analysis	YES
5519573	28785274	PS	PLoS5	Analyzed the data|Wrote the paper|Implemented reviewers comments	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5519573	28785274	PS	PLoS5	Analyzed the data|Wrote the paper|Implemented reviewers comments	Implemented reviewers comments	Performed the experiments	Investigation	YES
5519573	28785274	SO-F	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Implemented reviewers comments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5519573	28785274	SO-F	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Implemented reviewers comments	Analyzed the data	Analyzed the data	Formal analysis	YES
5519573	28785274	SO-F	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Implemented reviewers comments	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5519573	28785274	SO-F	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Implemented reviewers comments	Implemented reviewers comments	Performed the experiments	Investigation	YES
5433954	28332121	All authors	2	have critically revised the manuscript for important intellectual content and approved the final version of the article|read and approved the final manuscript	have critically revised the manuscript for important intellectual content and approved the final version of the article	Wrote the paper	Writing - Review & Editing	YES
5433954	28332121	All authors	2	have critically revised the manuscript for important intellectual content and approved the final version of the article|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5433954	28332121	CS	2	contributed to study design and to data collection	contributed to study design and to data collection	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources	YES
5433954	28332121	KS	2	contributed to study design and to data collection	contributed to study design and to data collection	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources	YES
5433954	28332121	OAA	2	contributed to study design and to data collection	contributed to study design and to data collection	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources	YES
5433954	28332121	TDB	2	aided in statistical analyses	aided in statistical analyses	Analyzed the data	Formal analysis	YES
5433954	28332121	TU	2	contributed to study design and to data collection	contributed to study design and to data collection	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources	YES
5433954	28332121	TVL	2	contributed to drafting the initial version of the manuscript and helped conceive the study design	contributed to drafting the initial version of the manuscript and helped conceive the study design	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
524357	15462684	AT	2	carried out the sequencing of pcr products and participated in the sequence alignments	carried out the sequencing of pcr products and participated in the sequence alignments	Performed the experiments	Investigation	YES
524357	15462684	CS	2	carried out the sequence analysis, pcr amplification and southern analysis	carried out the sequence analysis, pcr amplification and southern analysis	Performed the experiments	Investigation	YES
524357	15462684	RKM	2	conceived of the study, and participated in its design and coordination	conceived of the study, and participated in its design and coordination	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
524357	15462684	SS	2	participated in sequence analysis and dna isolation from several organisms	participated in sequence analysis and dna isolation from several organisms	Performed the experiments	Investigation	YES
4941541	27453779	A Sule	2	conceived the study, managed the patients, collected the data and wrote up the report	conceived the study, managed the patients, collected the data and wrote up the report	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Data curation|Investigation|Writing - Original Draft	YES
4941541	27453779	Dr Nzegwu	2	read the pathology slides, read and made contributions to the report and agreed with the final version	read the pathology slides, read and made contributions to the report and agreed with the final version	Performed the experiments	Investigation	YES
4404358	25894203	BX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404358	25894203	BX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404358	25894203	BX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404358	25894203	BX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404358	25894203	BX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404358	25894203	HX	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404358	25894203	HX	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404358	25894203	HX	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404358	25894203	QY	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404358	25894203	QY	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404358	25894203	XL	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4404358	25894203	XM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404358	25894203	YW	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404358	25894203	YW	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404358	25894203	YW	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404358	25894203	YZ	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5418696	28484508	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5418696	28484508	BNM	2	conceived and designed the study|participated in data collection|drafted the initial manuscript|interpreted the analysis	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5418696	28484508	BNM	2	conceived and designed the study|participated in data collection|drafted the initial manuscript|interpreted the analysis	participated in data collection	Performed the experiments	Investigation	YES
5418696	28484508	BNM	2	conceived and designed the study|participated in data collection|drafted the initial manuscript|interpreted the analysis	drafted the initial manuscript	Wrote the paper	Writing - Original Draft	YES
5418696	28484508	BNM	2	conceived and designed the study|participated in data collection|drafted the initial manuscript|interpreted the analysis	interpreted the analysis	Analyzed the data	Formal analysis	YES
5418696	28484508	IK	2	compiled and analysed data|drafted the initial manuscript|interpreted the analysis	compiled and analysed data	Analyzed the data	Data curation|Formal analysis	YES
5418696	28484508	IK	2	compiled and analysed data|drafted the initial manuscript|interpreted the analysis	drafted the initial manuscript	Wrote the paper	Writing - Original Draft	YES
5418696	28484508	IK	2	compiled and analysed data|drafted the initial manuscript|interpreted the analysis	interpreted the analysis	Analyzed the data	Formal analysis	YES
5418696	28484508	IN	2	participated in data collection	participated in data collection	Performed the experiments	Investigation	YES
5418696	28484508	JL	2	conceived and designed the study|compiled and analysed data	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5418696	28484508	JL	2	conceived and designed the study|compiled and analysed data	compiled and analysed data	Analyzed the data	Data curation|Formal analysis	YES
5418696	28484508	JW	2	participated in data collection|participated in the laboratory analyses	participated in data collection	Performed the experiments	Investigation	YES
5418696	28484508	JW	2	participated in data collection|participated in the laboratory analyses	participated in the laboratory analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5418696	28484508	PK	2	conceived and designed the study|participated in data collection|interpreted the analysis	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5418696	28484508	PK	2	conceived and designed the study|participated in data collection|interpreted the analysis	participated in data collection	Performed the experiments	Investigation	YES
5418696	28484508	PK	2	conceived and designed the study|participated in data collection|interpreted the analysis	interpreted the analysis	Analyzed the data	Formal analysis	YES
5418696	28484508	PM	2	conceived and designed the study|interpreted the analysis	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5418696	28484508	PM	2	conceived and designed the study|interpreted the analysis	interpreted the analysis	Analyzed the data	Formal analysis	YES
5418696	28484508	all authors	2	contributed to manuscript revising	contributed to manuscript revising	-	-	NO
5519581	28785271	All authors	2	agreed with the final version of the manuscript	agreed with the final version of the manuscript	-	-	NO
5519581	28785271	DL-B	2	assisted with the insect resistance assay and data analysis	assisted with the insect resistance assay and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5519581	28785271	JR	2	coordinated the study and assisted with the experimental design and with drafting the manuscript	coordinated the study and assisted with the experimental design and with drafting the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Project administration|Writing - Original Draft	YES
5519581	28785271	KM	2	assisted with the insect resistance assay and data analysis	assisted with the insect resistance assay and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5519581	28785271	VC	2	designed and performed the experiments, carried out the data analyses and drafted the manuscript	designed and performed the experiments, carried out the data analyses and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5519581	28785271	VJC	2	assisted with experimental design and transcriptome analyses	assisted with experimental design and transcriptome analyses	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5519581	28785271	VOC	2	collection and analysis	collection and analysis	-	-	NO
5597143	28970430	A.R.	PLoS52	provided constructive criticism of the manuscript	provided constructive criticism of the manuscript	Performed the experiments	Investigation	YES
5597143	28970430	D.V.	PLoS52	performed the experiments|analysed the data and wrote the initial version of the paper	performed the experiments	Performed the experiments	Investigation	YES
5597143	28970430	D.V.	PLoS52	performed the experiments|analysed the data and wrote the initial version of the paper	analysed the data and wrote the initial version of the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5597143	28970430	K.S.	PLoS52	performed the experiments|provided constructive criticism of the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5597143	28970430	K.S.	PLoS52	performed the experiments|provided constructive criticism of the manuscript	provided constructive criticism of the manuscript	Performed the experiments	Investigation	YES
4475708	26167477	Giulio Barteselli	2	contributed equally as first authors	contributed equally as first authors	-	-	NO
4475708	26167477	Maura Di Nicola	2	contributed equally as first authors	contributed equally as first authors	-	-	NO
5244568	28103801	JB	PLoS5	Conception and design of the experiments|Performed research|Analysis and interpretation of data|Wrote the paper	Conception and design of the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5244568	28103801	JB	PLoS5	Conception and design of the experiments|Performed research|Analysis and interpretation of data|Wrote the paper	Performed research	Performed the experiments	Investigation	YES
5244568	28103801	JB	PLoS5	Conception and design of the experiments|Performed research|Analysis and interpretation of data|Wrote the paper	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
5244568	28103801	JB	PLoS5	Conception and design of the experiments|Performed research|Analysis and interpretation of data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5244568	28103801	TB	PLoS5	Conception and design of the experiments|Analysis and interpretation of data|Wrote the paper	Conception and design of the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5244568	28103801	TB	PLoS5	Conception and design of the experiments|Analysis and interpretation of data|Wrote the paper	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
5244568	28103801	TB	PLoS5	Conception and design of the experiments|Analysis and interpretation of data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4653319	26584954	AH	2	designed the study|performed the statistical analyses|wrote the first draft of the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
4653319	26584954	AH	2	designed the study|performed the statistical analyses|wrote the first draft of the manuscript	performed the statistical analyses	Analyzed the data	Formal analysis	YES
4653319	26584954	AH	2	designed the study|performed the statistical analyses|wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
4653319	26584954	All authors	2	contributed to the interpretation of the data, critically revised the paper and approved its final version	contributed to the interpretation of the data, critically revised the paper and approved its final version	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
4653319	26584954	BL	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
4653319	26584954	GW	2	designed the study|performed the statistical analyses|wrote the first draft of the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
4653319	26584954	GW	2	designed the study|performed the statistical analyses|wrote the first draft of the manuscript	performed the statistical analyses	Analyzed the data	Formal analysis	YES
4653319	26584954	GW	2	designed the study|performed the statistical analyses|wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
4653319	26584954	HF	2	designed the study|wrote the first draft of the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
4653319	26584954	HF	2	designed the study|wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
4949399	27489623	C Foo	2	contributed to writing the manuscripts and conception and design of study	contributed to writing the manuscripts and conception and design of study	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
4949399	27489623	J Poon	2	contributed to conception and design of study	contributed to conception and design of study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4949399	27489623	L Law	2	contributed to conception and design of study and final approval of study	contributed to conception and design of study and final approval of study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4949399	27489623	Y Chan	2	contributed to writing the manuscripts and analyzing data	contributed to writing the manuscripts and analyzing data	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
5449314	28332119	All authors	2	fulfill the four authorship criteria as stated by the icmje|read and approved the final manuscript	fulfill the four authorship criteria as stated by the icmje	Analyzed the data	Formal analysis	YES
5449314	28332119	All authors	2	fulfill the four authorship criteria as stated by the icmje|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4404359	25893966	HS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404359	25893966	HS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404359	25893966	MK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404359	25893966	MK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404359	25893966	MK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404359	25893966	MK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404359	25893966	SW	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404359	25893966	SW	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404359	25893966	YF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404359	25893966	YF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404359	25893966	YF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404359	25893966	YF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404359	25893966	YF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5420083	28484509	AA	2	contributed data for the analysis	contributed data for the analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5420083	28484509	AK	2	contributed data for the analysis	contributed data for the analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5420083	28484509	All	2	patients have their data stored in both the site-level and centralized study databases for the purposes of research	patients have their data stored in both the site-level and centralized study databases for the purposes of research	Contributed reagents/materials/analysis tools	Software	YES
5420083	28484509	All authors	2	commented on the draft manuscript|read and approved the final manuscript	commented on the draft manuscript	Wrote the paper	Writing - Original Draft	YES
5420083	28484509	All authors	2	commented on the draft manuscript|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5420083	28484509	BS	2	contributed data for the analysis	contributed data for the analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5420083	28484509	DB	2	performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
5420083	28484509	DDC	2	contributed data for the analysis	contributed data for the analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5420083	28484509	EY	2	contributed data for the analysis	contributed data for the analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5420083	28484509	FZ	2	contributed data for the analysis	contributed data for the analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5420083	28484509	JYC	2	contributed data for the analysis	contributed data for the analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5420083	28484509	MPL	2	contributed data for the analysis	contributed data for the analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5420083	28484509	NK	2	contributed data for the analysis	contributed data for the analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5420083	28484509	NVK	2	contributed data for the analysis	contributed data for the analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5420083	28484509	OTN	2	contributed data for the analysis	contributed data for the analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5420083	28484509	PK	2	contributed data for the analysis	contributed data for the analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5420083	28484509	PSL	2	contributed data for the analysis	contributed data for the analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5420083	28484509	RC	2	contributed data for the analysis	contributed data for the analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5420083	28484509	RD	2	contributed data for the analysis	contributed data for the analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5420083	28484509	SK	2	initiated concept ideas|contributed data for the analysis	initiated concept ideas	Conceived and designed the experiments	Conceptualization	YES
5420083	28484509	SK	2	initiated concept ideas|contributed data for the analysis	contributed data for the analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5420083	28484509	SO	2	contributed data for the analysis	contributed data for the analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5420083	28484509	SP	2	contributed data for the analysis	contributed data for the analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5420083	28484509	SS	2	initiated concept ideas	initiated concept ideas	Conceived and designed the experiments	Conceptualization	YES
5420083	28484509	TAHOD	2	steering committee member	steering committee member	-	-	NO
5420083	28484509	TPM	2	contributed data for the analysis	contributed data for the analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5420083	28484509	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5420083	28484509	WR	2	contributed data for the analysis	contributed data for the analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5420083	28484509	WWW	2	contributed data for the analysis	contributed data for the analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5449354	28447332	T. Both	2	authors read and approved the final manuscript	authors read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5449354	28447332	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5244587	28100171	BJD	2	provided snp data set from generation 32	provided snp data set from generation 32	Contributed reagents/materials/analysis tools	Resources	YES
5244587	28100171	CFH	2	manage the virginia chicken lines, collected samples and provided dna	manage the virginia chicken lines, collected samples and provided dna	Performed the experiments	Investigation	YES
5244587	28100171	CMA	2	provided snp data set from generation 32	provided snp data set from generation 32	Contributed reagents/materials/analysis tools	Resources	YES
5244587	28100171	ML	2	performed analyses, with|wrote the manuscript	performed analyses, with	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5244587	28100171	ML	2	performed analyses, with|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5244587	28100171	OC	2	designed the study|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5244587	28100171	OC	2	designed the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5244587	28100171	PBS	2	designed the study|manage the virginia chicken lines, collected samples and provided dna	designed the study	Conceived and designed the experiments	Methodology	YES
5244587	28100171	PBS	2	designed the study|manage the virginia chicken lines, collected samples and provided dna	manage the virginia chicken lines, collected samples and provided dna	Performed the experiments	Investigation	YES
5244587	28100171	ZS	2	assisted with the with	assisted with the with	-	-	NO
5597144	28970431	Jeffrey Atkinson	2	wrote the first and subsequent revised versions of this article	wrote the first and subsequent revised versions of this article	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4655223	26593453	AM	2	analyzed and interpreted the data	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
4655223	26593453	AT	2	made substantial contributions to data acquisition	made substantial contributions to data acquisition	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4655223	26593453	CN	2	were responsible for conception and design of the study and helped to interpret the results	were responsible for conception and design of the study and helped to interpret the results	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
4655223	26593453	HW	2	were responsible for conception and design of the study and helped to interpret the results	were responsible for conception and design of the study and helped to interpret the results	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
4655223	26593453	NS	2	analyzed and interpreted the data	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
4655223	26593453	PM	2	made substantial contributions to data acquisition	made substantial contributions to data acquisition	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4655223	26593453	SG	2	were responsible for conception and design of the study and helped to interpret the results	were responsible for conception and design of the study and helped to interpret the results	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
4949773	27489624	Louis Riddez	4	The study concept and design was formed by	The study concept and design was formed by	Conceived and designed the experiments	Conceptualization|Methodology	YES
4949773	27489624	Rebecka Ahl	4	The study concept and design was formed by|analysis and interpretation was carried out by	The study concept and design was formed by	Conceived and designed the experiments	Conceptualization|Methodology	YES
4949773	27489624	Rebecka Ahl	4	The study concept and design was formed by|analysis and interpretation was carried out by	analysis and interpretation was carried out by	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4949773	27489624	Shahin Mohseni	4	The study concept and design was formed by|analysis and interpretation was carried out by	The study concept and design was formed by	Conceived and designed the experiments	Conceptualization|Methodology	YES
4949773	27489624	Shahin Mohseni	4	The study concept and design was formed by|analysis and interpretation was carried out by	analysis and interpretation was carried out by	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5519584	28785268	EM	2	collected phenotyping data	collected phenotyping data	Performed the experiments	Investigation	YES
5519584	28785268	FK	2	collected phenotyping data	collected phenotyping data	Performed the experiments	Investigation	YES
5519584	28785268	IN	2	collected phenotyping data|conducted ibd analysis|constructed the genetic map and performed qtl analysis	collected phenotyping data	Performed the experiments	Investigation	YES
5519584	28785268	IN	2	collected phenotyping data|conducted ibd analysis|constructed the genetic map and performed qtl analysis	conducted ibd analysis	Performed the experiments	Investigation	YES
5519584	28785268	IN	2	collected phenotyping data|conducted ibd analysis|constructed the genetic map and performed qtl analysis	constructed the genetic map and performed qtl analysis	Performed the experiments	Investigation	YES
5519584	28785268	JB	2	provided training and technical support on introgression analysis	provided training and technical support on introgression analysis	Performed the experiments	Investigation	YES
5519584	28785268	KS	2	collected phenotyping data	collected phenotyping data	Performed the experiments	Investigation	YES
5519584	28785268	M. All	2	authors read and approved the article	authors read and approved the article	-	-	NO
5519584	28785268	MF	2	conceived, designed, and managed the research	conceived, designed, and managed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5519584	28785268	MK	2	provided training and technical support on introgression analysis	provided training and technical support on introgression analysis	Performed the experiments	Investigation	YES
5519584	28785268	SR	2	provided scientific and bioinformatics support	provided scientific and bioinformatics support	-	Formal analysis	YES
5519584	28785268	TS	2	conducted ibd analysis	conducted ibd analysis	Performed the experiments	Investigation	YES
5449360	28332120	All authors	2	have read and approved the final manuscript	have read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5449360	28332120	The authors	2	report no financial or personal relationships, interests, and affiliations relevant to the subject matter of the manuscript	report no financial or personal relationships, interests, and affiliations relevant to the subject matter of the manuscript	-	-	NO
4404360	25894218	ALR	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4404360	25894218	ALR	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404360	25894218	HJM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4404360	25894218	HJM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404360	25894218	KADO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404360	25894218	KADO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404360	25894218	KADO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404360	25894218	KADO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404360	25894218	LBS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404360	25894218	LBS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404360	25894218	LBS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404360	25894218	LBS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404360	25894218	MAMG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404360	25894218	MAMG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4404360	25894218	MAMG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
3543790	23365539	X. Guo	2	are contributed equally to this work	are contributed equally to this work	-	-	NO
3543790	23365539	Z. Liu	2	are contributed equally to this work	are contributed equally to this work	-	-	NO
5952215	29506874	All authors	1	Acquisition of data|Critical review and revision	Acquisition of data	Performed the experiments	Investigation	YES
5952215	29506874	All authors	1	Acquisition of data|Critical review and revision	Critical review and revision	Wrote the paper	Writing - Review & Editing	YES
5952215	29506874	D.M.T.	1	Conception and design of the study|Drafting the manuscript or figures	Conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5952215	29506874	D.M.T.	1	Conception and design of the study|Drafting the manuscript or figures	Drafting the manuscript or figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5952215	29506874	G.S.G.	1	Conception and design of the study|Analysis and interpretation of data|Drafting the manuscript or figures	Conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5952215	29506874	G.S.G.	1	Conception and design of the study|Analysis and interpretation of data|Drafting the manuscript or figures	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
5952215	29506874	G.S.G.	1	Conception and design of the study|Analysis and interpretation of data|Drafting the manuscript or figures	Drafting the manuscript or figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5952215	29506874	N.Z.L.	1	Analysis and interpretation of data|Drafting the manuscript or figures	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
5952215	29506874	N.Z.L.	1	Analysis and interpretation of data|Drafting the manuscript or figures	Drafting the manuscript or figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5952215	29506874	R.D.S.P.	1	Drafting the manuscript or figures	Drafting the manuscript or figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5952215	29506874	R.M.	1	Conception and design of the study|Drafting the manuscript or figures|Drafting the manuscript or figures	Conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5952215	29506874	R.M.	1	Conception and design of the study|Drafting the manuscript or figures|Drafting the manuscript or figures	Drafting the manuscript or figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5952215	29506874	R.M.	1	Conception and design of the study|Drafting the manuscript or figures|Drafting the manuscript or figures	Drafting the manuscript or figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5952215	29506874	R.W.T.	1	Conception and design of the study|Drafting the manuscript or figures	Conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5952215	29506874	R.W.T.	1	Conception and design of the study|Drafting the manuscript or figures	Drafting the manuscript or figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5952215	29506874	Y.S.N.	1	Conception and design of the study|Analysis and interpretation of data|Drafting the manuscript or figures	Conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5952215	29506874	Y.S.N.	1	Conception and design of the study|Analysis and interpretation of data|Drafting the manuscript or figures	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
5952215	29506874	Y.S.N.	1	Conception and design of the study|Analysis and interpretation of data|Drafting the manuscript or figures	Drafting the manuscript or figures	Wrote the paper	Visualization|Writing - Original Draft	YES
4956904	27482378	Ken Ashwell	2	improvised research topic and assisted in final editing of the manuscript	improvised research topic and assisted in final editing of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4956904	27482378	Wenjie Zhong	2	is the main person who conducted this research, including literature review, data collection, data analysis as well as manuscript completion	is the main person who conducted this research, including literature review, data collection, data analysis as well as manuscript completion	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
524485	15469607	JB	2	participated in the design of the study, developed the senseamp reactions, and modified the reactions in response to qpcr validation results	participated in the design of the study, developed the senseamp reactions, and modified the reactions in response to qpcr validation results	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Validation	YES
524485	15469607	JS	2	participated in the design of the study, developed the senseamp reactions, and modified the reactions in response to qpcr validation results	participated in the design of the study, developed the senseamp reactions, and modified the reactions in response to qpcr validation results	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Validation	YES
524485	15469607	KH	2	participated in the design of the study, developed the senseamp reactions, and modified the reactions in response to qpcr validation results	participated in the design of the study, developed the senseamp reactions, and modified the reactions in response to qpcr validation results	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Validation	YES
524485	15469607	LAG	2	performed all qpcr assays, selected and designed primer pairs, developed databases holding all data, and prepared the first draft of the manuscript	performed all qpcr assays, selected and designed primer pairs, developed databases holding all data, and prepared the first draft of the manuscript	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Software|Writing - Original Draft	YES
524485	15469607	RCG	2	participated in the design of the study, developed the senseamp reactions, and modified the reactions in response to qpcr validation results|supervised senseamp development	participated in the design of the study, developed the senseamp reactions, and modified the reactions in response to qpcr validation results	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Validation	YES
524485	15469607	RCG	2	participated in the design of the study, developed the senseamp reactions, and modified the reactions in response to qpcr validation results|supervised senseamp development	supervised senseamp development	-	Supervision	YES
524485	15469607	RPH	2	conceived the study, supervised the qpcr assays, and coordinated work	conceived the study, supervised the qpcr assays, and coordinated work	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Project administration|Supervision	YES
5597145	28970432	All authors	PLoS52	reviewed and approved the manuscript	reviewed and approved the manuscript	Wrote the paper	Writing - Review & Editing	YES
5597145	28970432	Catherine Hanna	PLoS52	jointly conceived the idea and design of the project	jointly conceived the idea and design of the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5597145	28970432	Christopher Harlow	PLoS52	jointly conceived the idea and design of the project|implemented the project and collected the data|wrote the manuscript	jointly conceived the idea and design of the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5597145	28970432	Christopher Harlow	PLoS52	jointly conceived the idea and design of the project|implemented the project and collected the data|wrote the manuscript	implemented the project and collected the data	Performed the experiments	Investigation	YES
5597145	28970432	Christopher Harlow	PLoS52	jointly conceived the idea and design of the project|implemented the project and collected the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5597145	28970432	Faika Zanjani	PLoS52	jointly conceived the idea and design of the project	jointly conceived the idea and design of the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5597145	28970432	Holly Divine	PLoS52	jointly conceived the idea and design of the project|wrote the manuscript	jointly conceived the idea and design of the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5597145	28970432	Holly Divine	PLoS52	jointly conceived the idea and design of the project|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5597145	28970432	Karen Blumenschein	PLoS52	jointly conceived the idea and design of the project|wrote the manuscript	jointly conceived the idea and design of the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5597145	28970432	Karen Blumenschein	PLoS52	jointly conceived the idea and design of the project|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5597145	28970432	Lynne Eckmann	PLoS52	jointly conceived the idea and design of the project|implemented the project and collected the data	jointly conceived the idea and design of the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5597145	28970432	Lynne Eckmann	PLoS52	jointly conceived the idea and design of the project|implemented the project and collected the data	implemented the project and collected the data	Performed the experiments	Investigation	YES
5597145	28970432	Yevgeniya Gokun	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5422965	28482927	AF	2	analysed data, and interpreted the results|all contributed to writing the draft of the manuscript and provided critical review of the manuscript	analysed data, and interpreted the results	Analyzed the data	Formal analysis	YES
5422965	28482927	AF	2	analysed data, and interpreted the results|all contributed to writing the draft of the manuscript and provided critical review of the manuscript	all contributed to writing the draft of the manuscript and provided critical review of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5422965	28482927	All authors	2	have made substantial contribution to the conception, design, gathering, analysis and/or interpretation of data and a contribution to the writing and intellectual content of the article|have read and approved the manuscript	have made substantial contribution to the conception, design, gathering, analysis and/or interpretation of data and a contribution to the writing and intellectual content of the article	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Resources|Writing - Original Draft	YES
5422965	28482927	All authors	2	have made substantial contribution to the conception, design, gathering, analysis and/or interpretation of data and a contribution to the writing and intellectual content of the article|have read and approved the manuscript	have read and approved the manuscript	-	-	NO
5422965	28482927	CK	2	formulated the research questions and the approach on analysis strategy|all contributed to writing the draft of the manuscript and provided critical review of the manuscript	formulated the research questions and the approach on analysis strategy	Conceived and designed the experiments	Conceptualization	YES
5422965	28482927	CK	2	formulated the research questions and the approach on analysis strategy|all contributed to writing the draft of the manuscript and provided critical review of the manuscript	all contributed to writing the draft of the manuscript and provided critical review of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5422965	28482927	DCHS	2	created the study design of the umbrella study	created the study design of the umbrella study	Conceived and designed the experiments	Methodology	YES
5422965	28482927	DS	2	is principal investigator of the psychosocial component of the dchs and contributed to the analysis strategy	is principal investigator of the psychosocial component of the dchs and contributed to the analysis strategy	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
5422965	28482927	KC	2	analysed data, and interpreted the results|all contributed to writing the draft of the manuscript and provided critical review of the manuscript	analysed data, and interpreted the results	Analyzed the data	Formal analysis	YES
5422965	28482927	KC	2	analysed data, and interpreted the results|all contributed to writing the draft of the manuscript and provided critical review of the manuscript	all contributed to writing the draft of the manuscript and provided critical review of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5422965	28482927	KD	2	formulated the research questions and the approach on analysis strategy|all contributed to writing the draft of the manuscript and provided critical review of the manuscript	formulated the research questions and the approach on analysis strategy	Conceived and designed the experiments	Conceptualization	YES
5422965	28482927	KD	2	formulated the research questions and the approach on analysis strategy|all contributed to writing the draft of the manuscript and provided critical review of the manuscript	all contributed to writing the draft of the manuscript and provided critical review of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5422965	28482927	NK	2	managed the co-ordination of data collection	managed the co-ordination of data collection	Performed the experiments|Analyzed the data	Data curation|Investigation|Project administration	YES
4662682	26613900	DC	2	wrote and revised the manuscript for submission	wrote and revised the manuscript for submission	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4662682	26613900	GM	2	wrote and revised the manuscript for submission	wrote and revised the manuscript for submission	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4662682	26613900	M-LN	2	wrote and revised the manuscript for submission	wrote and revised the manuscript for submission	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4662682	26613900	MM	2	conceived the study|prepared and analyzed the data|wrote and revised the manuscript for submission	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4662682	26613900	MM	2	conceived the study|prepared and analyzed the data|wrote and revised the manuscript for submission	prepared and analyzed the data	Analyzed the data	Formal analysis	YES
4662682	26613900	MM	2	conceived the study|prepared and analyzed the data|wrote and revised the manuscript for submission	wrote and revised the manuscript for submission	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4662682	26613900	RR	2	wrote and revised the manuscript for submission	wrote and revised the manuscript for submission	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4662682	26613900	TB	2	conceived the study|wrote and revised the manuscript for submission	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4662682	26613900	TB	2	conceived the study|wrote and revised the manuscript for submission	wrote and revised the manuscript for submission	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5519606	28785269	GK	2	conceived the project|planned the experiments|performed all experiments|wrote the manuscript	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5519606	28785269	GK	2	conceived the project|planned the experiments|performed all experiments|wrote the manuscript	planned the experiments	Conceived and designed the experiments	Conceptualization	YES
5519606	28785269	GK	2	conceived the project|planned the experiments|performed all experiments|wrote the manuscript	performed all experiments	Performed the experiments	Investigation	YES
5519606	28785269	GK	2	conceived the project|planned the experiments|performed all experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5519606	28785269	MV	2	planned the experiments	planned the experiments	Conceived and designed the experiments	Conceptualization	YES
5519606	28785269	RS	2	conceived the project|planned the experiments|wrote the manuscript	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5519606	28785269	RS	2	conceived the project|planned the experiments|wrote the manuscript	planned the experiments	Conceived and designed the experiments	Conceptualization	YES
5519606	28785269	RS	2	conceived the project|planned the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5519606	28785269	YS	2	conceived the project|planned the experiments	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5519606	28785269	YS	2	conceived the project|planned the experiments	planned the experiments	Conceived and designed the experiments	Conceptualization	YES
5519606	28785269	all authors	2	contributed to the final version	contributed to the final version	-	-	NO
5457743	28447334	ACC	2	participated in recruitment and assessment of patients and controls, data analysis, and writing	participated in recruitment and assessment of patients and controls, data analysis, and writing	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation	YES
5457743	28447334	AJMB	2	participated in nmr data collection, analysis, and writing	participated in nmr data collection, analysis, and writing	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation	YES
5457743	28447334	AL	2	participated in conception, fund raising, and writing	participated in conception, fund raising, and writing	Conceived and designed the experiments|Wrote the paper	Conceptualization|Funding acquisition	YES
5457743	28447334	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5457743	28447334	CDM	2	participated in data collection, analysis, and writing	participated in data collection, analysis, and writing	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation	YES
5457743	28447334	EA	2	participated in recruitment and assessment of patients and controls, data analysis, and writing	participated in recruitment and assessment of patients and controls, data analysis, and writing	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation	YES
5457743	28447334	EB	2	participated in all the steps of conception, execution, and diffusion of results	participated in all the steps of conception, execution, and diffusion of results	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5457743	28447334	GMP	2	participated in nmr data collection, analysis, and writing	participated in nmr data collection, analysis, and writing	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation	YES
5457743	28447334	LR	2	participated in data collection, analysis, and writing	participated in data collection, analysis, and writing	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation	YES
5457743	28447334	LT	2	participated in all the steps of conception, execution, and diffusion of results	participated in all the steps of conception, execution, and diffusion of results	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5457743	28447334	MAFH	2	participated in all the steps of conception, execution, and diffusion of results	participated in all the steps of conception, execution, and diffusion of results	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5457743	28447334	MNN	2	participated in recruitment and assessment of patients and controls, data analysis, and writing	participated in recruitment and assessment of patients and controls, data analysis, and writing	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation	YES
5457743	28447334	MP	2	participated in recruitment and assessment of patients and controls, data analysis, and writing	participated in recruitment and assessment of patients and controls, data analysis, and writing	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation	YES
5457743	28447334	MZG	2	participated in data collection, analysis, and writing	participated in data collection, analysis, and writing	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation	YES
5457743	28447334	QC	2	participated in recruitment and assessment of patients and controls, data analysis, and writing	participated in recruitment and assessment of patients and controls, data analysis, and writing	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation	YES
5457743	28447334	RP	2	participated in all the steps of conception, execution, and diffusion of results	participated in all the steps of conception, execution, and diffusion of results	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5457743	28447334	SS	2	participated in data collection, data analysis, and writing of manuscript	participated in data collection, data analysis, and writing of manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5457743	28447334	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
4404361	25893435	BW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4404361	25893435	JH	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404361	25893435	JH	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404361	25893435	LZ	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4404361	25893435	SC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404361	25893435	WZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404361	25893435	WZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404361	25893435	WZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404361	25893435	WZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404361	25893435	YP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
3543792	23346016	K. Maschuw	2	contributed equally to this work	contributed equally to this work	-	-	NO
3543792	23346016	V. Fendrich	2	contributed equally to this work	contributed equally to this work	-	-	NO
5248466	28103802	AD	2	conceived the project|performed experiments|designed data analyses|interpreted data|wrote the manuscript	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5248466	28103802	AD	2	conceived the project|performed experiments|designed data analyses|interpreted data|wrote the manuscript	performed experiments	Performed the experiments	Investigation	YES
5248466	28103802	AD	2	conceived the project|performed experiments|designed data analyses|interpreted data|wrote the manuscript	designed data analyses	Conceived and designed the experiments|Analyzed the data	Formal analysis	YES
5248466	28103802	AD	2	conceived the project|performed experiments|designed data analyses|interpreted data|wrote the manuscript	interpreted data	Analyzed the data	Formal analysis	YES
5248466	28103802	AD	2	conceived the project|performed experiments|designed data analyses|interpreted data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5248466	28103802	AF-S	2	interpreted data	interpreted data	Analyzed the data	Formal analysis	YES
5248466	28103802	AY	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5248466	28103802	All authors	2	contributed to the preparation of the manuscript	contributed to the preparation of the manuscript	Wrote the paper	Writing - Original Draft	YES
5248466	28103802	CB	2	designed data analyses	designed data analyses	Conceived and designed the experiments|Analyzed the data	Formal analysis	YES
5248466	28103802	DL	2	designed data analyses	designed data analyses	Conceived and designed the experiments|Analyzed the data	Formal analysis	YES
5248466	28103802	DM	2	designed data analyses|interpreted data	designed data analyses	Conceived and designed the experiments|Analyzed the data	Formal analysis	YES
5248466	28103802	DM	2	designed data analyses|interpreted data	interpreted data	Analyzed the data	Formal analysis	YES
5248466	28103802	JF	2	designed data analyses	designed data analyses	Conceived and designed the experiments|Analyzed the data	Formal analysis	YES
5248466	28103802	KH	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5248466	28103802	KM	2	performed experiments|designed data analyses|interpreted data|wrote the manuscript	performed experiments	Performed the experiments	Investigation	YES
5248466	28103802	KM	2	performed experiments|designed data analyses|interpreted data|wrote the manuscript	designed data analyses	Conceived and designed the experiments|Analyzed the data	Formal analysis	YES
5248466	28103802	KM	2	performed experiments|designed data analyses|interpreted data|wrote the manuscript	interpreted data	Analyzed the data	Formal analysis	YES
5248466	28103802	KM	2	performed experiments|designed data analyses|interpreted data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6013750	29685790	A.C.	2	was involved in protocol development, assessment of subjects and statistical analysis	was involved in protocol development, assessment of subjects and statistical analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
6013750	29685790	All authors	2	discussed the results and commented on the manuscript	discussed the results and commented on the manuscript	-	-	NO
6013750	29685790	E.E.	2	were involved in protocol development and assessment of subjects	were involved in protocol development and assessment of subjects	Conceived and designed the experiments	Methodology	YES
6013750	29685790	J.D.	2	was the lead statistician	was the lead statistician	Analyzed the data	Formal analysis	YES
6013750	29685790	J.L.	2	assessed subjects, maintained data base, performed statistical analysis and was primary author of manuscript	assessed subjects, maintained data base, performed statistical analysis and was primary author of manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Software|Writing - Original Draft	YES
6013750	29685790	K.M.	2	were involved in protocol development and assessment of subjects	were involved in protocol development and assessment of subjects	Conceived and designed the experiments	Methodology	YES
6013750	29685790	P.N.	2	provided oversight of protocol and scientific design	provided oversight of protocol and scientific design	Conceived and designed the experiments	Methodology|Supervision	YES
6013750	29685790	V.M.	2	developed the mri sequence protocol and image processing	developed the mri sequence protocol and image processing	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Investigation|Methodology|Visualization	YES
4959920	27489617	Study Design	1	Spychal	Spychal	-	-	NO
5597146	28970433	H.M.	PLoS52	performed the experiments|contributed reagents/materials/analysis tools	performed the experiments	Performed the experiments	Investigation	YES
5597146	28970433	H.M.	PLoS52	performed the experiments|contributed reagents/materials/analysis tools	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5597146	28970433	H.N.	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5597146	28970433	H.N.	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5597146	28970433	H.N.	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5597146	28970433	H.N.	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5597146	28970433	I.F.	PLoS52	contributed reagents/materials/analysis tools	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5597146	28970433	I.N.	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5597146	28970433	K.N.	PLoS52	contributed reagents/materials/analysis tools	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5597146	28970433	K.S.	PLoS52	performed the experiments|contributed reagents/materials/analysis tools	performed the experiments	Performed the experiments	Investigation	YES
5597146	28970433	K.S.	PLoS52	performed the experiments|contributed reagents/materials/analysis tools	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5597146	28970433	M.I.	PLoS52	performed the experiments|contributed reagents/materials/analysis tools	performed the experiments	Performed the experiments	Investigation	YES
5597146	28970433	M.I.	PLoS52	performed the experiments|contributed reagents/materials/analysis tools	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5597146	28970433	N.M.	PLoS52	conceived and designed the experiments|contributed reagents/materials/analysis tools	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5597146	28970433	N.M.	PLoS52	conceived and designed the experiments|contributed reagents/materials/analysis tools	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5597146	28970433	N.Y.	PLoS52	conceived and designed the experiments|contributed reagents/materials/analysis tools	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5597146	28970433	N.Y.	PLoS52	conceived and designed the experiments|contributed reagents/materials/analysis tools	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5597146	28970433	S.K.	PLoS52	conceived and designed the experiments|contributed reagents/materials/analysis tools	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5597146	28970433	S.K.	PLoS52	conceived and designed the experiments|contributed reagents/materials/analysis tools	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5597146	28970433	S.M.	PLoS52	performed the experiments|contributed reagents/materials/analysis tools	performed the experiments	Performed the experiments	Investigation	YES
5597146	28970433	S.M.	PLoS52	performed the experiments|contributed reagents/materials/analysis tools	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5597146	28970433	T.A.	PLoS52	contributed reagents/materials/analysis tools	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5597146	28970433	T.N.	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|contributed reagents/materials/analysis tools|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5597146	28970433	T.N.	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|contributed reagents/materials/analysis tools|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5597146	28970433	T.N.	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|contributed reagents/materials/analysis tools|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5597146	28970433	T.N.	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|contributed reagents/materials/analysis tools|wrote the paper	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5597146	28970433	T.N.	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|contributed reagents/materials/analysis tools|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5597146	28970433	T.O.	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5597146	28970433	T.O.	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5597146	28970433	T.O.	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5597146	28970433	T.O.	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4666907	26626715	CKF	2	assisted with all of the above, reviewed and edited and contributed to the manuscript	assisted with all of the above, reviewed and edited and contributed to the manuscript	Wrote the paper	Writing - Review & Editing	YES
4666907	26626715	EP-FC	2	assisted with all of the above, independently verified search and record assessment, reviewed and edited and contributed to the manuscript	assisted with all of the above, independently verified search and record assessment, reviewed and edited and contributed to the manuscript	Performed the experiments|Wrote the paper	Validation|Writing - Review & Editing	YES
4666907	26626715	JFH	2	reviewed and edited and contributed to the manuscript	reviewed and edited and contributed to the manuscript	Wrote the paper	Writing - Review & Editing	YES
4666907	26626715	JHE	2	assisted with design of the protocol, reviewed and edited and contributed to the manuscript	assisted with design of the protocol, reviewed and edited and contributed to the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
4666907	26626715	JHM	2	assisted with all of the above, independently verified search and record assessment, reviewed and edited and contributed to the manuscript	assisted with all of the above, independently verified search and record assessment, reviewed and edited and contributed to the manuscript	Performed the experiments|Wrote the paper	Validation|Writing - Review & Editing	YES
4666907	26626715	NAM	2	designed review protocol, developed search strategy, developed and piloted data extraction instrument, conducted search, assessed search records, extracted data, compiled results, wrote manuscript and designed figures and tables	designed review protocol, developed search strategy, developed and piloted data extraction instrument, conducted search, assessed search records, extracted data, compiled results, wrote manuscript and designed figures and tables	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Investigation|Methodology|Visualization|Writing - Original Draft|Writing - Review & Editing	YES
5519628	28785277	DG	PLoS52	performed the experiments|carried out data analysis and wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5519628	28785277	DG	PLoS52	performed the experiments|carried out data analysis and wrote the manuscript	carried out data analysis and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5519628	28785277	JZ	PLoS52	performed the experiments|carried out data analysis and wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5519628	28785277	JZ	PLoS52	performed the experiments|carried out data analysis and wrote the manuscript	carried out data analysis and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5519628	28785277	SF	PLoS52	designed the experiments|helped in preparing the manuscript and in interpretation of the analyses during constructive discussions	designed the experiments	Conceived and designed the experiments	Methodology	YES
5519628	28785277	SF	PLoS52	designed the experiments|helped in preparing the manuscript and in interpretation of the analyses during constructive discussions	helped in preparing the manuscript and in interpretation of the analyses during constructive discussions	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5519628	28785277	XW	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5457744	28393327	AB	2	conceived the study, took care of patients treatment and follow-up, and prepared the manuscript	conceived the study, took care of patients treatment and follow-up, and prepared the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
5457744	28393327	AP	2	carried out and interpreted the neurologic aspects	carried out and interpreted the neurologic aspects	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5457744	28393327	All the authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5457744	28393327	Biomedical Sciences	2	the university of cagliari, and works at the lithium clinic as a specialist in neurology since 1976	the university of cagliari, and works at the lithium clinic as a specialist in neurology since 1976	-	-	NO
5457744	28393327	CC	2	coordinated the clinical work and took care of patients treatment and follow-up|is a specialist in clinical pharmacology and works at the lithium clinic since 2001	coordinated the clinical work and took care of patients treatment and follow-up	Performed the experiments	Investigation|Project administration	YES
5457744	28393327	CC	2	coordinated the clinical work and took care of patients treatment and follow-up|is a specialist in clinical pharmacology and works at the lithium clinic since 2001	is a specialist in clinical pharmacology and works at the lithium clinic since 2001	Performed the experiments	Investigation	YES
5457744	28393327	CS	2	performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
5457744	28393327	FC	2	contributed to the literature search and clinical management|has graduated in medicine after an internship at the lithium clinic and part of this work is part of her doctoral thesis	contributed to the literature search and clinical management	-	Formal analysis	YES
5457744	28393327	FC	2	contributed to the literature search and clinical management|has graduated in medicine after an internship at the lithium clinic and part of this work is part of her doctoral thesis	has graduated in medicine after an internship at the lithium clinic and part of this work is part of her doctoral thesis	-	-	NO
5457744	28393327	MDZ	2	supervised the clinical work, interpreted the results, and reviewed the manuscript	supervised the clinical work, interpreted the results, and reviewed the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Supervision|Writing - Review & Editing	YES
5457744	28393327	MP	2	took care of patients treatment and follow-up	took care of patients treatment and follow-up	Performed the experiments	Investigation	YES
5457744	28393327	Medical Science	2	public health, the university of cagliari	public health, the university of cagliari	-	-	NO
5457744	28393327	RA	2	took care of patients treatment and follow-up|is a specialist in clinical pharmacology and works at the lithium clinic since 2001	took care of patients treatment and follow-up	Performed the experiments	Investigation	YES
5457744	28393327	RA	2	took care of patients treatment and follow-up|is a specialist in clinical pharmacology and works at the lithium clinic since 2001	is a specialist in clinical pharmacology and works at the lithium clinic since 2001	Performed the experiments	Investigation	YES
5457744	28393327	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
4404362	25893441	A. Santo	PLoS5	Wrote the paper|Acquisition of data	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404362	25893441	A. Santo	PLoS5	Wrote the paper|Acquisition of data	Acquisition of data	Performed the experiments	Investigation	YES
4404362	25893441	A. Suzuki	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404362	25893441	A. Suzuki	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404362	25893441	ED	PLoS5	Wrote the paper|Acquisition of data	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404362	25893441	ED	PLoS5	Wrote the paper|Acquisition of data	Acquisition of data	Performed the experiments	Investigation	YES
4404362	25893441	H. Oshitani	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404362	25893441	H. Oshitani	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404362	25893441	H. Otomaru	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404362	25893441	H. Otomaru	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404362	25893441	H. Otomaru	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404362	25893441	H. Otomaru	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404362	25893441	JO	PLoS5	Wrote the paper|Acquisition of data	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404362	25893441	JO	PLoS5	Wrote the paper|Acquisition of data	Acquisition of data	Performed the experiments	Investigation	YES
4404362	25893441	MO	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404362	25893441	MO	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404362	25893441	MS	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404362	25893441	MS	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404362	25893441	RT	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404362	25893441	RT	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404362	25893441	SL	PLoS5	Wrote the paper|Acquisition of data	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404362	25893441	SL	PLoS5	Wrote the paper|Acquisition of data	Acquisition of data	Performed the experiments	Investigation	YES
4404362	25893441	TK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404362	25893441	TK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404362	25893441	TK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404362	25893441	VT	PLoS5	Wrote the paper|Acquisition of data	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404362	25893441	VT	PLoS5	Wrote the paper|Acquisition of data	Acquisition of data	Performed the experiments	Investigation	YES
5450046	28558783	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5450046	28558783	PCJ	2	drafted the first manuscript	drafted the first manuscript	Wrote the paper	Writing - Original Draft	YES
5450046	28558783	PVF	2	drafted the first manuscript	drafted the first manuscript	Wrote the paper	Writing - Original Draft	YES
4668283	26632480	MAW	2	all contributed to the preparation of the manuscript	all contributed to the preparation of the manuscript	Wrote the paper	Writing - Original Draft	YES
4668283	26632480	MB	2	all contributed to the preparation of the manuscript	all contributed to the preparation of the manuscript	Wrote the paper	Writing - Original Draft	YES
4668283	26632480	PSS	2	all contributed to the preparation of the manuscript	all contributed to the preparation of the manuscript	Wrote the paper	Writing - Original Draft	YES
4668283	26632480	SK	2	all contributed to the preparation of the manuscript	all contributed to the preparation of the manuscript	Wrote the paper	Writing - Original Draft	YES
4475739	26167496	Claudio Stamile	2	contributed equally to this work	contributed equally to this work	-	-	NO
4475739	26167496	Michele Cavallari	2	contributed equally to this work	contributed equally to this work	-	-	NO
6013780	29748033	All authors	2	were involved in editing and approval of the final manuscript	were involved in editing and approval of the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6013780	29748033	B.D.S.	2	designed and performed the quantitative statistical analysis of the single-phase model|interpreted the data and wrote the manuscript	designed and performed the quantitative statistical analysis of the single-phase model	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
6013780	29748033	B.D.S.	2	designed and performed the quantitative statistical analysis of the single-phase model|interpreted the data and wrote the manuscript	interpreted the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6013780	29748033	C.S.	2	performed the laboratory experiments|interpreted the data and wrote the manuscript	performed the laboratory experiments	Performed the experiments	Investigation	YES
6013780	29748033	C.S.	2	performed the laboratory experiments|interpreted the data and wrote the manuscript	interpreted the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6013780	29748033	D.M.T.	2	designed and directed the study	designed and directed the study	Conceived and designed the experiments	Methodology|Supervision	YES
6013780	29748033	J.C.M.	2	collected the human colonoscopic biopsy material	collected the human colonoscopic biopsy material	Performed the experiments	Investigation	YES
6013780	29748033	L.C.G.	2	designed and directed the study|interpreted the data and wrote the manuscript	designed and directed the study	Conceived and designed the experiments	Methodology|Supervision	YES
6013780	29748033	L.C.G.	2	designed and directed the study|interpreted the data and wrote the manuscript	interpreted the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6013780	29748033	R.H.	2	interpreted the data and wrote the manuscript	interpreted the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6013780	29748033	T.B.L.K.	2	designed and directed the study	designed and directed the study	Conceived and designed the experiments	Methodology|Supervision	YES
4960347	27489621	Christopher Barton	7	Study design, review	Study design, review	Conceived and designed the experiments	Methodology	YES
4960347	27489621	Hamid Mohamadlou	7	Data collection, data analysis	Data collection, data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4960347	27489621	Jake Calvert	7	Study design, data collection, data analysis, writing	Study design, data collection, data analysis, writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology	YES
4960347	27489621	Jana Hoffman	7	Study design, writing	Study design, writing	Conceived and designed the experiments|Wrote the paper	Methodology	YES
4960347	27489621	Melissa Jay	7	Data collection, data analysis	Data collection, data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4960347	27489621	Qingqing Mao	7	Data collection, data analysis	Data collection, data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4960347	27489621	Ritankar Das	7	Study design, writing	Study design, writing	Conceived and designed the experiments|Wrote the paper	Methodology	YES
4960347	27489621	Thomas Desauutels	7	Study design, data collection, data analysis, writing	Study design, data collection, data analysis, writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology	YES
4960347	27489621	Uli Chettipally	7	Study design, review	Study design, review	Conceived and designed the experiments	Methodology	YES
5248489	28103797	AC	2	contributed to the design of the study, analysed and interpreted the data and wrote the paper	contributed to the design of the study, analysed and interpreted the data and wrote the paper	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Original Draft	YES
5248489	28103797	ADR	2	contributed to the interpretation of results and edited the manuscript	contributed to the interpretation of results and edited the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5248489	28103797	CJ	2	contributed to the analysis and interpretation of results	contributed to the analysis and interpretation of results	Analyzed the data	Formal analysis	YES
5248489	28103797	GC	2	contributed to the design of the study, the interpretation of data and was a major contributor in writing the manuscript	contributed to the design of the study, the interpretation of data and was a major contributor in writing the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Original Draft	YES
5248489	28103797	HM	2	provide facilities to collect dna samples in nepal and edited the manuscript	provide facilities to collect dna samples in nepal and edited the manuscript	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Resources|Writing - Review & Editing	YES
5248489	28103797	NP	2	edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5248489	28103797	PG	2	provided genotype data for populations from the pamir mountain range	provided genotype data for populations from the pamir mountain range	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5248489	28103797	PR	2	edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5597147	28970434	Chad Friece	2	collected and reviewed the data|substantially contributed to writing the paper	collected and reviewed the data	Performed the experiments	Investigation	YES
5597147	28970434	Chad Friece	2	collected and reviewed the data|substantially contributed to writing the paper	substantially contributed to writing the paper	Wrote the paper	Writing - Original Draft	YES
5597147	28970434	Darrell Newcomer	2	substantially contributed to writing the paper	substantially contributed to writing the paper	Wrote the paper	Writing - Original Draft	YES
5597147	28970434	Evangelina Castaneda	2	substantially contributed to writing the paper	substantially contributed to writing the paper	Wrote the paper	Writing - Original Draft	YES
5597147	28970434	Nicki Roderman	2	reviewed, analyzed and substantially contributed to writing the paper	reviewed, analyzed and substantially contributed to writing the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5597147	28970434	Sondra Davis	2	collected and reviewed the data|substantially contributed to writing the paper	collected and reviewed the data	Performed the experiments	Investigation	YES
5597147	28970434	Sondra Davis	2	collected and reviewed the data|substantially contributed to writing the paper	substantially contributed to writing the paper	Wrote the paper	Writing - Original Draft	YES
5520323	28785276	All authors	PLoS52	have read the final manuscript	have read the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5520323	28785276	DS	PLoS52	designed the project|wrote the manuscript	designed the project	Conceived and designed the experiments	Methodology	YES
5520323	28785276	DS	PLoS52	designed the project|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5520323	28785276	JL	PLoS52	designed the project|analyzed the data|wrote the manuscript	designed the project	Conceived and designed the experiments	Methodology	YES
5520323	28785276	JL	PLoS52	designed the project|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5520323	28785276	JL	PLoS52	designed the project|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5520323	28785276	NS	PLoS52	designed the project|performed the experiments|acquired the metabolomics and proteomics data, respectively|analyzed the data|wrote the manuscript	designed the project	Conceived and designed the experiments	Methodology	YES
5520323	28785276	NS	PLoS52	designed the project|performed the experiments|acquired the metabolomics and proteomics data, respectively|analyzed the data|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5520323	28785276	NS	PLoS52	designed the project|performed the experiments|acquired the metabolomics and proteomics data, respectively|analyzed the data|wrote the manuscript	acquired the metabolomics and proteomics data, respectively	Performed the experiments	Investigation	YES
5520323	28785276	NS	PLoS52	designed the project|performed the experiments|acquired the metabolomics and proteomics data, respectively|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5520323	28785276	NS	PLoS52	designed the project|performed the experiments|acquired the metabolomics and proteomics data, respectively|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5520323	28785276	PM	PLoS52	performed the experiments|acquired the metabolomics and proteomics data, respectively	performed the experiments	Performed the experiments	Investigation	YES
5520323	28785276	PM	PLoS52	performed the experiments|acquired the metabolomics and proteomics data, respectively	acquired the metabolomics and proteomics data, respectively	Performed the experiments	Investigation	YES
5520323	28785276	SK	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5520323	28785276	SM	PLoS52	analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5520323	28785276	SM	PLoS52	analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5520323	28785276	The authors	PLoS52	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	Performed the experiments	Investigation	YES
5520323	28785276	WH	PLoS52	performed the experiments|acquired the metabolomics and proteomics data, respectively|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5520323	28785276	WH	PLoS52	performed the experiments|acquired the metabolomics and proteomics data, respectively|analyzed the data	acquired the metabolomics and proteomics data, respectively	Performed the experiments	Investigation	YES
5520323	28785276	WH	PLoS52	performed the experiments|acquired the metabolomics and proteomics data, respectively|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
4668284	26632479	Andrew Grulich	2	also contributed to the preparation of this paper	also contributed to the preparation of this paper	-	-	NO
4668284	26632479	Iryna Zablotska	2	assumed primary responsibility for writing the manuscript	assumed primary responsibility for writing the manuscript	Wrote the paper	Writing - Original Draft	YES
4668284	26632479	Tim Spelman	2	also contributed to the preparation of this paper	also contributed to the preparation of this paper	-	-	NO
5461226	28589489	AG	2	wrote the protocol|performed the primary statistical analysis and drafted the first version of the manuscript	wrote the protocol	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5461226	28589489	AG	2	wrote the protocol|performed the primary statistical analysis and drafted the first version of the manuscript	performed the primary statistical analysis and drafted the first version of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5461226	28589489	All authors	2	read and approved the final manuscript|have made substantial contributions to conception and design, been involved in revising the manuscript, given final approval of the version to be published and agreed to be accountable for all aspects of the work	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5461226	28589489	All authors	2	read and approved the final manuscript|have made substantial contributions to conception and design, been involved in revising the manuscript, given final approval of the version to be published and agreed to be accountable for all aspects of the work	have made substantial contributions to conception and design, been involved in revising the manuscript, given final approval of the version to be published and agreed to be accountable for all aspects of the work	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5461226	28589489	MV	2	wrote the protocol|did all the patient recruitment|performed the primary statistical analysis and drafted the first version of the manuscript|drafted subsequent versions of the manuscript	wrote the protocol	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5461226	28589489	MV	2	wrote the protocol|did all the patient recruitment|performed the primary statistical analysis and drafted the first version of the manuscript|drafted subsequent versions of the manuscript	did all the patient recruitment	Performed the experiments	Investigation	YES
5461226	28589489	MV	2	wrote the protocol|did all the patient recruitment|performed the primary statistical analysis and drafted the first version of the manuscript|drafted subsequent versions of the manuscript	performed the primary statistical analysis and drafted the first version of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5461226	28589489	MV	2	wrote the protocol|did all the patient recruitment|performed the primary statistical analysis and drafted the first version of the manuscript|drafted subsequent versions of the manuscript	drafted subsequent versions of the manuscript	Wrote the paper	Writing - Original Draft	YES
5461226	28589489	TS	2	wrote the protocol|did all the patient recruitment|performed the primary statistical analysis and drafted the first version of the manuscript|drafted subsequent versions of the manuscript|declare that they have no competing interests	wrote the protocol	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5461226	28589489	TS	2	wrote the protocol|did all the patient recruitment|performed the primary statistical analysis and drafted the first version of the manuscript|drafted subsequent versions of the manuscript|declare that they have no competing interests	did all the patient recruitment	Performed the experiments	Investigation	YES
5461226	28589489	TS	2	wrote the protocol|did all the patient recruitment|performed the primary statistical analysis and drafted the first version of the manuscript|drafted subsequent versions of the manuscript|declare that they have no competing interests	performed the primary statistical analysis and drafted the first version of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5461226	28589489	TS	2	wrote the protocol|did all the patient recruitment|performed the primary statistical analysis and drafted the first version of the manuscript|drafted subsequent versions of the manuscript|declare that they have no competing interests	drafted subsequent versions of the manuscript	Wrote the paper	Writing - Original Draft	YES
5461226	28589489	TS	2	wrote the protocol|did all the patient recruitment|performed the primary statistical analysis and drafted the first version of the manuscript|drafted subsequent versions of the manuscript|declare that they have no competing interests	declare that they have no competing interests	-	-	NO
4404363	25894334	HK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404363	25894334	HK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404363	25894334	IS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404363	25894334	IS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404363	25894334	IS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404363	25894334	IS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404363	25894334	JA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404363	25894334	JA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404363	25894334	JA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404363	25894334	JA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404363	25894334	MK	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4404363	25894334	MS	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4404363	25894334	UW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404363	25894334	UW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404363	25894334	UW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404363	25894334	UW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4670453	26637523	AHS	2	reviewed and revised the manuscript	reviewed and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4670453	26637523	AK	2	conducted the transition programme and gathered the clinical data reported	conducted the transition programme and gathered the clinical data reported	Performed the experiments	Investigation	YES
4670453	26637523	All co-authors	2	reviewed and approved the final manuscript	reviewed and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4670453	26637523	RH	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4670453	26637523	SD	2	conducted the transition programme and gathered the clinical data reported	conducted the transition programme and gathered the clinical data reported	Performed the experiments	Investigation	YES
4670453	26637523	SP	2	conducted the transition programme and gathered the clinical data reported	conducted the transition programme and gathered the clinical data reported	Performed the experiments	Investigation	YES
4670453	26637523	SW	2	conducted the transition programme and gathered the clinical data reported	conducted the transition programme and gathered the clinical data reported	Performed the experiments	Investigation	YES
5249001	28105936	AB	1	Study concept and design|Data analysis|Drafting manuscript|Revising article critically for important intellectual content	Study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5249001	28105936	AB	1	Study concept and design|Data analysis|Drafting manuscript|Revising article critically for important intellectual content	Data analysis	Analyzed the data	Formal analysis	YES
5249001	28105936	AB	1	Study concept and design|Data analysis|Drafting manuscript|Revising article critically for important intellectual content	Drafting manuscript	Wrote the paper	Writing - Original Draft	YES
5249001	28105936	AB	1	Study concept and design|Data analysis|Drafting manuscript|Revising article critically for important intellectual content	Revising article critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5249001	28105936	KK	1	Data analysis|Drafting manuscript|Revising article critically for important intellectual content	Data analysis	Analyzed the data	Formal analysis	YES
5249001	28105936	KK	1	Data analysis|Drafting manuscript|Revising article critically for important intellectual content	Drafting manuscript	Wrote the paper	Writing - Original Draft	YES
5249001	28105936	KK	1	Data analysis|Drafting manuscript|Revising article critically for important intellectual content	Revising article critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5249001	28105936	MS	1	Data analysis|Revising article critically for important intellectual content	Data analysis	Analyzed the data	Formal analysis	YES
5249001	28105936	MS	1	Data analysis|Revising article critically for important intellectual content	Revising article critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5249001	28105936	NT	1	Data analysis|Revising article critically for important intellectual content	Data analysis	Analyzed the data	Formal analysis	YES
5249001	28105936	NT	1	Data analysis|Revising article critically for important intellectual content	Revising article critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5249001	28105936	OKM	1	Data analysis|Revising article critically for important intellectual content	Data analysis	Analyzed the data	Formal analysis	YES
5249001	28105936	OKM	1	Data analysis|Revising article critically for important intellectual content	Revising article critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
6013782	29703528	All authors	2	contributed to the manuscript review and approved the final version	contributed to the manuscript review and approved the final version	Wrote the paper	Writing - Review & Editing	YES
6013782	29703528	DL	2	had primary responsibility for final content	had primary responsibility for final content	-	-	NO
6013782	29703528	JSZ	2	analyzed data and performed statistical analysis|had primary responsibility for final content	analyzed data and performed statistical analysis	Analyzed the data	Formal analysis	YES
6013782	29703528	JSZ	2	analyzed data and performed statistical analysis|had primary responsibility for final content	had primary responsibility for final content	-	-	NO
5597148	28970435	All authors	2	contributed to interpretation of data, manuscript preparation, and approved the version to be published	contributed to interpretation of data, manuscript preparation, and approved the version to be published	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
5597148	28970435	Anna Birna Almarsdottir	2	analyzed the interview data	analyzed the interview data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5597148	28970435	Anna Bryndis Blondal	2	completed the data collection and was the participating researcher|analyzed the interview data	completed the data collection and was the participating researcher	Performed the experiments	Investigation	YES
5597148	28970435	Anna Bryndis Blondal	2	completed the data collection and was the participating researcher|analyzed the interview data	analyzed the interview data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5474299	28623917	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5474299	28623917	BS	PLoS52	conceived the study, designed the experiments, and analyzed the data|contributed to reagents and materials|wrote the article	conceived the study, designed the experiments, and analyzed the data	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
5474299	28623917	BS	PLoS52	conceived the study, designed the experiments, and analyzed the data|contributed to reagents and materials|wrote the article	contributed to reagents and materials	Contributed reagents/materials/analysis tools	Resources	YES
5474299	28623917	BS	PLoS52	conceived the study, designed the experiments, and analyzed the data|contributed to reagents and materials|wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
5474299	28623917	GZ	PLoS52	performed the experiments|wrote the article	performed the experiments	Performed the experiments	Investigation	YES
5474299	28623917	GZ	PLoS52	performed the experiments|wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
5474299	28623917	HW	PLoS52	conceived the study, designed the experiments, and analyzed the data|wrote the article	conceived the study, designed the experiments, and analyzed the data	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
5474299	28623917	HW	PLoS52	conceived the study, designed the experiments, and analyzed the data|wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
5474299	28623917	LL	PLoS52	conceived the study, designed the experiments, and analyzed the data|performed the experiments|wrote the article	conceived the study, designed the experiments, and analyzed the data	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
5474299	28623917	LL	PLoS52	conceived the study, designed the experiments, and analyzed the data|performed the experiments|wrote the article	performed the experiments	Performed the experiments	Investigation	YES
5474299	28623917	LL	PLoS52	conceived the study, designed the experiments, and analyzed the data|performed the experiments|wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
5474299	28623917	PC	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5474299	28623917	TZ	PLoS52	contributed to reagents and materials	contributed to reagents and materials	Contributed reagents/materials/analysis tools	Resources	YES
5474299	28623917	WL	PLoS52	conceived the study, designed the experiments, and analyzed the data|contributed to reagents and materials|wrote the article	conceived the study, designed the experiments, and analyzed the data	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
5474299	28623917	WL	PLoS52	conceived the study, designed the experiments, and analyzed the data|contributed to reagents and materials|wrote the article	contributed to reagents and materials	Contributed reagents/materials/analysis tools	Resources	YES
5474299	28623917	WL	PLoS52	conceived the study, designed the experiments, and analyzed the data|contributed to reagents and materials|wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
5468355	28447333	All the authors	2	have contributed to the study design and writing of this manuscript|read and approved the final manuscript	have contributed to the study design and writing of this manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5468355	28447333	All the authors	2	have contributed to the study design and writing of this manuscript|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5468355	28447333	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
4404364	25894586	DSW	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404364	25894586	JW	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4404364	25894586	LMW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4404364	25894586	LNS	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4404364	25894586	LYZ	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404364	25894586	SHS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4404364	25894586	TC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404364	25894586	YN	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404364	25894586	YXQ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5522864	28791034	DD	2	planned the experiment|collected data|interpreted data|wrote the manuscript	planned the experiment	Conceived and designed the experiments	Conceptualization	YES
5522864	28791034	DD	2	planned the experiment|collected data|interpreted data|wrote the manuscript	collected data	Performed the experiments	Investigation	YES
5522864	28791034	DD	2	planned the experiment|collected data|interpreted data|wrote the manuscript	interpreted data	Analyzed the data	Formal analysis	YES
5522864	28791034	DD	2	planned the experiment|collected data|interpreted data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5522864	28791034	IA	2	developed and provided the original e-1-7-6 transgenic line	developed and provided the original e-1-7-6 transgenic line	Performed the experiments	Investigation	YES
5522864	28791034	JJ	2	planned the experiment	planned the experiment	Conceived and designed the experiments	Conceptualization	YES
5522864	28791034	JM	2	collected data	collected data	Performed the experiments	Investigation	YES
5522864	28791034	LG	2	collected data|interpreted data|wrote the manuscript	collected data	Performed the experiments	Investigation	YES
5522864	28791034	LG	2	collected data|interpreted data|wrote the manuscript	interpreted data	Analyzed the data	Formal analysis	YES
5522864	28791034	LG	2	collected data|interpreted data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5522864	28791034	MW	2	planned the experiment|interpreted data|wrote the manuscript	planned the experiment	Conceived and designed the experiments	Conceptualization	YES
5522864	28791034	MW	2	planned the experiment|interpreted data|wrote the manuscript	interpreted data	Analyzed the data	Formal analysis	YES
5522864	28791034	MW	2	planned the experiment|interpreted data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4404365	25894998	BMK	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Assisted in designing the study	Performed the experiments	Performed the experiments	Investigation	YES
4404365	25894998	BMK	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Assisted in designing the study	Analyzed the data	Analyzed the data	Formal analysis	YES
4404365	25894998	BMK	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Assisted in designing the study	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4404365	25894998	BMK	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Assisted in designing the study	Assisted in designing the study	Conceived and designed the experiments	Methodology	YES
4404365	25894998	HRK	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404365	25894998	HRK	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404365	25894998	KWK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4404365	25894998	KWK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4404365	25894998	KWK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4404365	25894998	KWK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404365	25894998	MLC	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4404365	25894998	SHL	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4670832	26639118	AN	2	contributed to the manuscript and approved the final version	contributed to the manuscript and approved the final version	-	-	NO
4670832	26639118	CW	2	contributed to the manuscript and approved the final version	contributed to the manuscript and approved the final version	-	-	NO
4670832	26639118	HR	2	contributed to the manuscript and approved the final version	contributed to the manuscript and approved the final version	-	-	NO
4670832	26639118	MFC	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4670832	26639118	MM	2	contributed to the manuscript and approved the final version	contributed to the manuscript and approved the final version	-	-	NO
4670832	26639118	SLH	2	contributed to the manuscript and approved the final version	contributed to the manuscript and approved the final version	-	-	NO
6013786	29685792	AJBT	2	conceived the study|designed the study|wrote the manuscript with contributions from all authors	conceived the study	Conceived and designed the experiments	Conceptualization	YES
6013786	29685792	AJBT	2	conceived the study|designed the study|wrote the manuscript with contributions from all authors	designed the study	Conceived and designed the experiments	Methodology	YES
6013786	29685792	AJBT	2	conceived the study|designed the study|wrote the manuscript with contributions from all authors	wrote the manuscript with contributions from all authors	Wrote the paper	Writing - Original Draft	YES
6013786	29685792	EL	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
6013786	29685792	JA	2	designed the study|are the principal investigators of the best-d trial|provided senior supervision	designed the study	Conceived and designed the experiments	Methodology	YES
6013786	29685792	JA	2	designed the study|are the principal investigators of the best-d trial|provided senior supervision	are the principal investigators of the best-d trial	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
6013786	29685792	JA	2	designed the study|are the principal investigators of the best-d trial|provided senior supervision	provided senior supervision	-	Supervision	YES
6013786	29685792	JCK	2	conceived the study|designed the study|provided senior supervision|wrote the manuscript with contributions from all authors	conceived the study	Conceived and designed the experiments	Conceptualization	YES
6013786	29685792	JCK	2	conceived the study|designed the study|provided senior supervision|wrote the manuscript with contributions from all authors	designed the study	Conceived and designed the experiments	Methodology	YES
6013786	29685792	JCK	2	conceived the study|designed the study|provided senior supervision|wrote the manuscript with contributions from all authors	provided senior supervision	-	Supervision	YES
6013786	29685792	JCK	2	conceived the study|designed the study|provided senior supervision|wrote the manuscript with contributions from all authors	wrote the manuscript with contributions from all authors	Wrote the paper	Writing - Original Draft	YES
6013786	29685792	KP	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
6013786	29685792	MH	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
6013786	29685792	RC	2	designed the study|are the principal investigators of the best-d trial|provided senior supervision	designed the study	Conceived and designed the experiments	Methodology	YES
6013786	29685792	RC	2	designed the study|are the principal investigators of the best-d trial|provided senior supervision	are the principal investigators of the best-d trial	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
6013786	29685792	RC	2	designed the study|are the principal investigators of the best-d trial|provided senior supervision	provided senior supervision	-	Supervision	YES
5512819	28716149	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5512819	28716149	CN	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5512819	28716149	GM	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5512819	28716149	KC	2	supervised all stages of the study and reviewed and provided critical inputs for writing the manuscript	supervised all stages of the study and reviewed and provided critical inputs for writing the manuscript	Wrote the paper	Supervision|Writing - Original Draft|Writing - Review & Editing	YES
5512819	28716149	KP	2	were responsible for data collection and data entry|analyzed data	were responsible for data collection and data entry	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5512819	28716149	KP	2	were responsible for data collection and data entry|analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5512819	28716149	PC	2	were responsible for data collection and data entry	were responsible for data collection and data entry	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5512819	28716149	PL	2	supervised all stages of the study and reviewed and provided critical inputs for writing the manuscript	supervised all stages of the study and reviewed and provided critical inputs for writing the manuscript	Wrote the paper	Supervision|Writing - Original Draft|Writing - Review & Editing	YES
5512819	28716149	SCC	2	supervised all stages of the study and reviewed and provided critical inputs for writing the manuscript	supervised all stages of the study and reviewed and provided critical inputs for writing the manuscript	Wrote the paper	Supervision|Writing - Original Draft|Writing - Review & Editing	YES
5512819	28716149	SS	2	conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5512819	28716149	ST	2	conceived the study|were responsible for data collection and data entry	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5512819	28716149	ST	2	conceived the study|were responsible for data collection and data entry	were responsible for data collection and data entry	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5512819	28716149	SY	2	conceived the study|analyzed data|wrote the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5512819	28716149	SY	2	conceived the study|analyzed data|wrote the manuscript	analyzed data	Analyzed the data	Formal analysis	YES
5512819	28716149	SY	2	conceived the study|analyzed data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5512819	28716149	VK	2	conceived the study|supervised all stages of the study and reviewed and provided critical inputs for writing the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5512819	28716149	VK	2	conceived the study|supervised all stages of the study and reviewed and provided critical inputs for writing the manuscript	supervised all stages of the study and reviewed and provided critical inputs for writing the manuscript	Wrote the paper	Supervision|Writing - Original Draft|Writing - Review & Editing	YES
5495819	28405955	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5495819	28405955	GM	2	contributed to interpretation of data and critically revised the manuscript	contributed to interpretation of data and critically revised the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
5495819	28405955	LT	2	oversaw the meta-analysis and critically revised the paper	oversaw the meta-analysis and critically revised the paper	Analyzed the data|Wrote the paper	Formal analysis|Supervision|Writing - Review & Editing	YES
5495819	28405955	MM	2	critically revised the manuscript and performed the systematic search and meta-analysis	critically revised the manuscript and performed the systematic search and meta-analysis	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
5495819	28405955	MP	2	wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
5495819	28405955	PS	2	contributed to interpretation of data and critically revised the manuscript	contributed to interpretation of data and critically revised the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
5495819	28405955	SP	2	performed the dermatological consultation and critically revised the manuscript	performed the dermatological consultation and critically revised the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5495819	28405955	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5597149	28970436	A.O.	PLoS52	made preliminary mapping of the curriculum|performed curriculum mapping|analyzed data	made preliminary mapping of the curriculum	-	-	NO
5597149	28970436	A.O.	PLoS52	made preliminary mapping of the curriculum|performed curriculum mapping|analyzed data	performed curriculum mapping	Performed the experiments	Investigation	YES
5597149	28970436	A.O.	PLoS52	made preliminary mapping of the curriculum|performed curriculum mapping|analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5597149	28970436	All authors	PLoS52	provided useful criticism and suggestions during paper writing	provided useful criticism and suggestions during paper writing	Wrote the paper	-	YES
5597149	28970436	B.B.	PLoS52	designed, constructed and leaded the process of curriculum mapping and analyzing|prepared preliminary matrix courses/competences|made preliminary mapping of the curriculum|wrote the paper	designed, constructed and leaded the process of curriculum mapping and analyzing	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5597149	28970436	B.B.	PLoS52	designed, constructed and leaded the process of curriculum mapping and analyzing|prepared preliminary matrix courses/competences|made preliminary mapping of the curriculum|wrote the paper	prepared preliminary matrix courses/competences	-	-	NO
5597149	28970436	B.B.	PLoS52	designed, constructed and leaded the process of curriculum mapping and analyzing|prepared preliminary matrix courses/competences|made preliminary mapping of the curriculum|wrote the paper	made preliminary mapping of the curriculum	-	-	NO
5597149	28970436	B.B.	PLoS52	designed, constructed and leaded the process of curriculum mapping and analyzing|prepared preliminary matrix courses/competences|made preliminary mapping of the curriculum|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5597149	28970436	I.G.	PLoS52	made preliminary mapping of the curriculum|performed curriculum mapping	made preliminary mapping of the curriculum	-	-	NO
5597149	28970436	I.G.	PLoS52	made preliminary mapping of the curriculum|performed curriculum mapping	performed curriculum mapping	Performed the experiments	Investigation	YES
5597149	28970436	M.K.	PLoS52	performed curriculum mapping|analyzed data|wrote the paper	performed curriculum mapping	Performed the experiments	Investigation	YES
5597149	28970436	M.K.	PLoS52	performed curriculum mapping|analyzed data|wrote the paper	analyzed data	Analyzed the data	Formal analysis	YES
5597149	28970436	M.K.	PLoS52	performed curriculum mapping|analyzed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5597149	28970436	N.H.	PLoS52	performed curriculum mapping|analyzed data	performed curriculum mapping	Performed the experiments	Investigation	YES
5597149	28970436	N.H.	PLoS52	performed curriculum mapping|analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5597149	28970436	T.G.	PLoS52	prepared preliminary matrix courses/competences|performed curriculum mapping|analyzed data|wrote the paper	prepared preliminary matrix courses/competences	-	-	NO
5597149	28970436	T.G.	PLoS52	prepared preliminary matrix courses/competences|performed curriculum mapping|analyzed data|wrote the paper	performed curriculum mapping	Performed the experiments	Investigation	YES
5597149	28970436	T.G.	PLoS52	prepared preliminary matrix courses/competences|performed curriculum mapping|analyzed data|wrote the paper	analyzed data	Analyzed the data	Formal analysis	YES
5597149	28970436	T.G.	PLoS52	prepared preliminary matrix courses/competences|performed curriculum mapping|analyzed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5597149	28970436	T.V.	PLoS52	made preliminary mapping of the curriculum|performed curriculum mapping	made preliminary mapping of the curriculum	-	-	NO
5597149	28970436	T.V.	PLoS52	made preliminary mapping of the curriculum|performed curriculum mapping	performed curriculum mapping	Performed the experiments	Investigation	YES
5249006	28105943	AI	PLoS52	conceived the study, supervised the experiments, performed most of the experiments|wrote the manuscript	conceived the study, supervised the experiments, performed most of the experiments	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Supervision	YES
5249006	28105943	AI	PLoS52	conceived the study, supervised the experiments, performed most of the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5249006	28105943	DL	PLoS52	conceived the study, supervised the experiments, performed most of the experiments	conceived the study, supervised the experiments, performed most of the experiments	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Supervision	YES
5249006	28105943	GA	PLoS52	analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5249006	28105943	GA	PLoS52	analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5249006	28105943	RS	PLoS52	analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5249006	28105943	RS	PLoS52	analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5249006	28105943	SV	PLoS52	conceived the study, supervised the experiments, performed most of the experiments|wrote the manuscript	conceived the study, supervised the experiments, performed most of the experiments	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Supervision	YES
5249006	28105943	SV	PLoS52	conceived the study, supervised the experiments, performed most of the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5249006	28105943	VG	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5522869	28791033	AM	2	data sampling and analysis|ur analysis and manuscript writing	data sampling and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5522869	28791033	AM	2	data sampling and analysis|ur analysis and manuscript writing	ur analysis and manuscript writing	Wrote the paper	Writing - Original Draft	YES
5522869	28791033	DO	2	data sampling and analysis|ur analysis and manuscript writing	data sampling and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5522869	28791033	DO	2	data sampling and analysis|ur analysis and manuscript writing	ur analysis and manuscript writing	Wrote the paper	Writing - Original Draft	YES
5522869	28791033	RI	2	ur analysis and manuscript writing	ur analysis and manuscript writing	Wrote the paper	Writing - Original Draft	YES
5522869	28791033	UR	2	data sampling and analysis	data sampling and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5522869	28791033	VM	2	data sampling and analysis|ur analysis and manuscript writing	data sampling and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5522869	28791033	VM	2	data sampling and analysis|ur analysis and manuscript writing	ur analysis and manuscript writing	Wrote the paper	Writing - Original Draft	YES
4971229	27508080	Ahmed Hammad	7	data collection	data collection	Performed the experiments	Investigation	YES
4971229	27508080	Alison Bradley	7	data interpretation, writing papaer	data interpretation, writing papaer	Analyzed the data|Wrote the paper	Formal analysis	YES
4971229	27508080	Arijit Mukherjee	7	study concept and design	study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4971229	27508080	Zilfiqar Hanif	7	study concept, design data analysis and interpretation, writing paper	study concept, design data analysis and interpretation, writing paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
4670833	26639112	W. This	2	article was written by all authors and they read and approved the final version	article was written by all authors and they read and approved the final version	Wrote the paper	Writing - Original Draft	YES
4971230	27508079	Ali Tecirli	7	data analysis	data analysis	Analyzed the data	Formal analysis	YES
4971230	27508079	Ali Toprak	7	follow-up	follow-up	-	-	NO
4971230	27508079	Burak Yoldas	7	writing, study design, final revisions	writing, study design, final revisions	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
4971230	27508079	Deniz Cankaya	7	study design, critical revisions	study design, critical revisions	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
4971230	27508079	Enver Kilic	7	statistics	statistics	Analyzed the data	Formal analysis	YES
4971230	27508079	Kemal Andic	7	writing, final revisions	writing, final revisions	Wrote the paper	Writing - Review & Editing	YES
4971230	27508079	Olgun Bingol	7	data collection	data collection	Performed the experiments	Investigation	YES
4971230	27508079	Yalcin Tabak	7	study design, critical revisions	study design, critical revisions	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5597150	28970437	A.G.	PLoS52	prepared the tools and performed the mapping process	prepared the tools and performed the mapping process	Performed the experiments	Investigation	YES
5597150	28970437	A.S.	PLoS52	conceived and designed the experiments|prepared the tools and performed the mapping process|analyzed the data and wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5597150	28970437	A.S.	PLoS52	conceived and designed the experiments|prepared the tools and performed the mapping process|analyzed the data and wrote the paper	prepared the tools and performed the mapping process	Performed the experiments	Investigation	YES
5597150	28970437	A.S.	PLoS52	conceived and designed the experiments|prepared the tools and performed the mapping process|analyzed the data and wrote the paper	analyzed the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5597150	28970437	J.D.	PLoS52	prepared the tools and performed the mapping process	prepared the tools and performed the mapping process	Performed the experiments	Investigation	YES
5597150	28970437	W.P.	PLoS52	prepared the tools and performed the mapping process	prepared the tools and performed the mapping process	Performed the experiments	Investigation	YES
6013932	29735415	L.M.W.	CRediT	Conceptualization|Formal analysis|Writing-Original draft|Visualization	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6013932	29735415	L.M.W.	CRediT	Conceptualization|Formal analysis|Writing-Original draft|Visualization	Formal analysis	Analyzed the data	Formal analysis	YES
6013932	29735415	L.M.W.	CRediT	Conceptualization|Formal analysis|Writing-Original draft|Visualization	Writing-Original draft	Wrote the paper	Writing - Original Draft	YES
6013932	29735415	L.M.W.	CRediT	Conceptualization|Formal analysis|Writing-Original draft|Visualization	Visualization	Analyzed the data	Visualization	YES
6013932	29735415	M.B.	CRediT	Conceptualization|Formal analysis|Writing-Original draft|Visualization|Supervision|Project administration|Funding acquisition	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6013932	29735415	M.B.	CRediT	Conceptualization|Formal analysis|Writing-Original draft|Visualization|Supervision|Project administration|Funding acquisition	Formal analysis	Analyzed the data	Formal analysis	YES
6013932	29735415	M.B.	CRediT	Conceptualization|Formal analysis|Writing-Original draft|Visualization|Supervision|Project administration|Funding acquisition	Writing-Original draft	Wrote the paper	Writing - Original Draft	YES
6013932	29735415	M.B.	CRediT	Conceptualization|Formal analysis|Writing-Original draft|Visualization|Supervision|Project administration|Funding acquisition	Visualization	Analyzed the data	Visualization	YES
6013932	29735415	M.B.	CRediT	Conceptualization|Formal analysis|Writing-Original draft|Visualization|Supervision|Project administration|Funding acquisition	Supervision	-	Supervision	YES
6013932	29735415	M.B.	CRediT	Conceptualization|Formal analysis|Writing-Original draft|Visualization|Supervision|Project administration|Funding acquisition	Project administration	-	Project administration	YES
6013932	29735415	M.B.	CRediT	Conceptualization|Formal analysis|Writing-Original draft|Visualization|Supervision|Project administration|Funding acquisition	Funding acquisition	-	Funding acquisition	YES
6013932	29735415	M.J.A.W.	CRediT	Funding acquisition	Funding acquisition	-	Funding acquisition	YES
6013932	29735415	M.O.D.	CRediT	Formal analysis	Formal analysis	Analyzed the data	Formal analysis	YES
5513397	28705213	AK	2	conceived the idea|equally wrote and critically edited the paper	conceived the idea	Conceived and designed the experiments	Conceptualization	YES
5513397	28705213	AK	2	conceived the idea|equally wrote and critically edited the paper	equally wrote and critically edited the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5513397	28705213	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5513397	28705213	GKN	2	equally wrote and critically edited the paper	equally wrote and critically edited the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5513397	28705213	STA	2	equally wrote and critically edited the paper	equally wrote and critically edited the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5597151	28970438	C.M.	2	conceived the project|who suggested further analyses|participated equally in the revision of the manuscript	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5597151	28970438	C.M.	2	conceived the project|who suggested further analyses|participated equally in the revision of the manuscript	who suggested further analyses	Analyzed the data	Formal analysis	YES
5597151	28970438	C.M.	2	conceived the project|who suggested further analyses|participated equally in the revision of the manuscript	participated equally in the revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5597151	28970438	J.A.	2	conceived the project|made the initial calculations and analyses|participated equally in the revision of the manuscript	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5597151	28970438	J.A.	2	conceived the project|made the initial calculations and analyses|participated equally in the revision of the manuscript	made the initial calculations and analyses	Analyzed the data	Formal analysis	YES
5597151	28970438	J.A.	2	conceived the project|made the initial calculations and analyses|participated equally in the revision of the manuscript	participated equally in the revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5249009	28105922	AAI	PLoS52	conceived and designed the work|performed the experiments	conceived and designed the work	Conceived and designed the experiments	Conceptualization	YES
5249009	28105922	AAI	PLoS52	conceived and designed the work|performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5249009	28105922	ABY	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5249009	28105922	DAA	PLoS52	wrote the manuscript|performed bioinformatics analysis	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5249009	28105922	DAA	PLoS52	wrote the manuscript|performed bioinformatics analysis	performed bioinformatics analysis	Performed the experiments	Formal analysis|Investigation	YES
5249009	28105922	FMS	PLoS52	performed the experiments|analyzed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5249009	28105922	FMS	PLoS52	performed the experiments|analyzed the experiments	analyzed the experiments	Analyzed the data	Formal analysis	YES
5249009	28105922	KAD	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5249009	28105922	KAV	PLoS52	wrote the manuscript|conceived and designed the work	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5249009	28105922	KAV	PLoS52	wrote the manuscript|conceived and designed the work	conceived and designed the work	Conceived and designed the experiments	Conceptualization	YES
5249009	28105922	KGS	PLoS52	wrote the manuscript|performed bioinformatics analysis	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5249009	28105922	KGS	PLoS52	wrote the manuscript|performed bioinformatics analysis	performed bioinformatics analysis	Performed the experiments	Formal analysis|Investigation	YES
5249009	28105922	KIY	PLoS52	conceived and designed the work	conceived and designed the work	Conceived and designed the experiments	Conceptualization	YES
5249009	28105922	KaDV	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5249009	28105922	KoDV	PLoS52	conceived and designed the work	conceived and designed the work	Conceived and designed the experiments	Conceptualization	YES
5249009	28105922	LAV	PLoS52	performed bioinformatics analysis	performed bioinformatics analysis	Performed the experiments	Formal analysis|Investigation	YES
5249009	28105922	MAA	PLoS52	conceived and designed the work	conceived and designed the work	Conceived and designed the experiments	Conceptualization	YES
5249009	28105922	MNV	PLoS52	analyzed the experiments	analyzed the experiments	Analyzed the data	Formal analysis	YES
5249009	28105922	NKM	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5249009	28105922	PAY	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5249009	28105922	SAF	PLoS52	analyzed the experiments	analyzed the experiments	Analyzed the data	Formal analysis	YES
5249009	28105922	SAV	PLoS52	wrote the manuscript|performed the experiments|analyzed the experiments	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5249009	28105922	SAV	PLoS52	wrote the manuscript|performed the experiments|analyzed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5249009	28105922	SAV	PLoS52	wrote the manuscript|performed the experiments|analyzed the experiments	analyzed the experiments	Analyzed the data	Formal analysis	YES
5249009	28105922	SDV	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5249009	28105922	VNN	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5249009	28105922	ZA	PLoS52	performed bioinformatics analysis	performed bioinformatics analysis	Performed the experiments	Formal analysis|Investigation	YES
5249009	28105922	ZAR	PLoS52	conceived and designed the work	conceived and designed the work	Conceived and designed the experiments	Conceptualization	YES
5522872	28791032	AD	2	prepared various constructs	prepared various constructs	Performed the experiments	Investigation	YES
5522872	28791032	DK	2	conceived project|wrote portion of the manuscript	conceived project	Conceived and designed the experiments	Conceptualization	YES
5522872	28791032	DK	2	conceived project|wrote portion of the manuscript	wrote portion of the manuscript	Wrote the paper	Writing - Original Draft	YES
5522872	28791032	DM	2	prepared various constructs	prepared various constructs	Performed the experiments	Investigation	YES
5522872	28791032	GD	2	performed starch experiment	performed starch experiment	Performed the experiments	Investigation	YES
5522872	28791032	JC	2	performed imaging analysis for chlorophyll fluorescence measurements	performed imaging analysis for chlorophyll fluorescence measurements	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
5522872	28791032	JF	2	performed thylakoid import assays|wrote portion of the manuscript	performed thylakoid import assays	Performed the experiments	Investigation	YES
5522872	28791032	JF	2	performed thylakoid import assays|wrote portion of the manuscript	wrote portion of the manuscript	Wrote the paper	Writing - Original Draft	YES
5522872	28791032	JT	2	performed semi-quantitative rt pcr	performed semi-quantitative rt pcr	Performed the experiments	Investigation	YES
5522872	28791032	KK	2	performed western blot, in vivo spectroscopic assays, various fluorescence experiments|wrote portion of the manuscript	performed western blot, in vivo spectroscopic assays, various fluorescence experiments	Performed the experiments	Investigation	YES
5522872	28791032	KK	2	performed western blot, in vivo spectroscopic assays, various fluorescence experiments|wrote portion of the manuscript	wrote portion of the manuscript	Wrote the paper	Writing - Original Draft	YES
6013935	29759484	C.X.	PLoS52	coordinated the project	coordinated the project	-	Project administration	YES
6013935	29759484	D.F.	PLoS52	coordinated the project	coordinated the project	-	Project administration	YES
6013935	29759484	H.W.	PLoS52	designed this study|analyzed the results	designed this study	Conceived and designed the experiments	Methodology	YES
6013935	29759484	H.W.	PLoS52	designed this study|analyzed the results	analyzed the results	Analyzed the data	Formal analysis	YES
6013935	29759484	M.L.	PLoS52	designed this study|performed the experiments|analyzed the results	designed this study	Conceived and designed the experiments	Methodology	YES
6013935	29759484	M.L.	PLoS52	designed this study|performed the experiments|analyzed the results	performed the experiments	Performed the experiments	Investigation	YES
6013935	29759484	M.L.	PLoS52	designed this study|performed the experiments|analyzed the results	analyzed the results	Analyzed the data	Formal analysis	YES
6013935	29759484	S.Z.	PLoS52	performed the experiments|coordinated the project	performed the experiments	Performed the experiments	Investigation	YES
6013935	29759484	S.Z.	PLoS52	performed the experiments|coordinated the project	coordinated the project	-	Project administration	YES
6013935	29759484	T.Z.	PLoS52	designed this study|analyzed the results	designed this study	Conceived and designed the experiments	Methodology	YES
6013935	29759484	T.Z.	PLoS52	designed this study|analyzed the results	analyzed the results	Analyzed the data	Formal analysis	YES
6013935	29759484	W.C.	PLoS52	performed the experiments|analyzed the results	performed the experiments	Performed the experiments	Investigation	YES
6013935	29759484	W.C.	PLoS52	performed the experiments|analyzed the results	analyzed the results	Analyzed the data	Formal analysis	YES
4405000	25793528	CAC	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405000	25793528	CLH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405000	25793528	CLH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405000	25793528	CLH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405000	25793528	CLH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405000	25793528	MAP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405000	25793528	MAP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405000	25793528	MAP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405000	25793528	MAP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405000	25793528	MSD	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405000	25793528	MSD	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405000	25793528	MSD	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405000	25793528	NJR	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405000	25793528	NJR	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405000	25793528	NJR	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405000	25793528	RSZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405000	25793528	RSZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405000	25793528	RSZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405000	25793528	RSZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405000	25793528	WKM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405000	25793528	WKM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405000	25793528	WKM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5502006	28480482	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5502006	28480482	JHB	2	have contributed to study design, data collection, and clinical rating	have contributed to study design, data collection, and clinical rating	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources	YES
5502006	28480482	KL	2	have contributed to study design, data collection, and clinical rating	have contributed to study design, data collection, and clinical rating	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources	YES
5502006	28480482	KSH	2	have contributed to study design, data collection, and clinical rating|wrote the manuscript	have contributed to study design, data collection, and clinical rating	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources	YES
5502006	28480482	KSH	2	have contributed to study design, data collection, and clinical rating|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5502006	28480482	SWA	2	have contributed to study design, data collection, and clinical rating|wrote the manuscript	have contributed to study design, data collection, and clinical rating	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources	YES
5502006	28480482	SWA	2	have contributed to study design, data collection, and clinical rating|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5502006	28480482	SYY	2	have contributed to study design, data collection, and clinical rating	have contributed to study design, data collection, and clinical rating	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources	YES
5502006	28480482	TP	2	undertook the statistical analysis	undertook the statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5502006	28480482	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5502006	28480482	YC	2	have contributed to study design, data collection, and clinical rating|contributed to data collection and management, and chart review of the patients	have contributed to study design, data collection, and clinical rating	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources	YES
5502006	28480482	YC	2	have contributed to study design, data collection, and clinical rating|contributed to data collection and management, and chart review of the patients	contributed to data collection and management, and chart review of the patients	Performed the experiments	Investigation	YES
5502006	28480482	YKK	2	undertook the statistical analysis	undertook the statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4978218	27547397	Anita Hariprashad	7	Data collection, final approval. Asaf Gave, Joseph Sabat, and I	Data collection, final approval. Asaf Gave, Joseph Sabat, and I	Performed the experiments	Investigation	YES
4978218	27547397	Christine Wiest	7	Data collection, final approval. Asaf Gave, Joseph Sabat, and I	Data collection, final approval. Asaf Gave, Joseph Sabat, and I	Performed the experiments	Investigation	YES
4978218	27547397	David Lucido	7	Data analysis, final approval	Data analysis, final approval	Analyzed the data	Formal analysis	YES
4978218	27547397	Ezra Gillego	7	Data collection, final approval. Asaf Gave, Joseph Sabat, and I	Data collection, final approval. Asaf Gave, Joseph Sabat, and I	Performed the experiments	Investigation	YES
4978218	27547397	Michael Leitman	7	Manuscript preparation, final approval	Manuscript preparation, final approval	Wrote the paper	Writing - Original Draft	YES
4978218	27547397	Scott Gould	7	Data collection, final approval. Asaf Gave, Joseph Sabat, and I	Data collection, final approval. Asaf Gave, Joseph Sabat, and I	Performed the experiments	Investigation	YES
4978218	27547397	Shailyn Almonte	7	Data collection, final approval. Asaf Gave, Joseph Sabat, and I	Data collection, final approval. Asaf Gave, Joseph Sabat, and I	Performed the experiments	Investigation	YES
4978218	27547397	Simon D. Eiref	7	Concept and study design, data collection, manuscript and figure preparation, final approval	Concept and study design, data collection, manuscript and figure preparation, final approval	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Visualization|Writing - Original Draft	YES
5597152	28970439	Anna Agusti	PLoS52	conceived and designed the data base, procedure and performed the interventions, their recording and analysis	conceived and designed the data base, procedure and performed the interventions, their recording and analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Software	YES
5597152	28970439	Blanca Llagostera	PLoS52	conceived and designed the data base, procedure and performed the interventions, their recording and analysis	conceived and designed the data base, procedure and performed the interventions, their recording and analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Software	YES
5597152	28970439	Conxita Mestres	PLoS52	conceived and designed the data base, procedure and performed the interventions, their recording and analysis|wrote the paper	conceived and designed the data base, procedure and performed the interventions, their recording and analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Software	YES
5597152	28970439	Conxita Mestres	PLoS52	conceived and designed the data base, procedure and performed the interventions, their recording and analysis|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5597152	28970439	Marta Hernandez	PLoS52	conceived and designed the data base, procedure and performed the interventions, their recording and analysis	conceived and designed the data base, procedure and performed the interventions, their recording and analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Software	YES
5249017	28105923	AG	2	performed general supervision of the research group	performed general supervision of the research group	Performed the experiments	Investigation|Supervision	YES
5249017	28105923	EA	2	conceived and designed the experiments, sequenced, assembled and annotated the genomes of the bcg sub-strain generations|participated in data interpretation	conceived and designed the experiments, sequenced, assembled and annotated the genomes of the bcg sub-strain generations	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
5249017	28105923	EA	2	conceived and designed the experiments, sequenced, assembled and annotated the genomes of the bcg sub-strain generations|participated in data interpretation	participated in data interpretation	Analyzed the data	Formal analysis	YES
5249017	28105923	MK	2	conceived and designed the experiments, sequenced, assembled and annotated the genomes of the bcg sub-strain generations|performed genome map analysis and assisted in the preparation of figures and text	conceived and designed the experiments, sequenced, assembled and annotated the genomes of the bcg sub-strain generations	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
5249017	28105923	MK	2	conceived and designed the experiments, sequenced, assembled and annotated the genomes of the bcg sub-strain generations|performed genome map analysis and assisted in the preparation of figures and text	performed genome map analysis and assisted in the preparation of figures and text	Performed the experiments	Investigation|Visualization	YES
5249017	28105923	NR	2	was responsible for the phylogenetic analysis, contributed to data interpretation and manuscript writing	was responsible for the phylogenetic analysis, contributed to data interpretation and manuscript writing	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5249017	28105923	OV	2	conceived and designed the experiments, sequenced, assembled and annotated the genomes of the bcg sub-strain generations|supervised the study and contributed to manuscript writing	conceived and designed the experiments, sequenced, assembled and annotated the genomes of the bcg sub-strain generations	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
5249017	28105923	OV	2	conceived and designed the experiments, sequenced, assembled and annotated the genomes of the bcg sub-strain generations|supervised the study and contributed to manuscript writing	supervised the study and contributed to manuscript writing	Wrote the paper	Supervision|Writing - Original Draft	YES
5249017	28105923	VL	2	contributed reagents/materials tools	contributed reagents/materials tools	Contributed reagents/materials/analysis tools	Resources	YES
4670835	26639114	MLS	2	contributed significantly to the literature review and writing of the manuscript	contributed significantly to the literature review and writing of the manuscript	Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
4670835	26639114	MSM	2	contributed significantly to the literature review and writing of the manuscript	contributed significantly to the literature review and writing of the manuscript	Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
4670835	26639114	RCV	2	led the design and writing of the manuscript	led the design and writing of the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
4670835	26639114	WMN	2	contributed significantly to the design and revision of the manuscript	contributed significantly to the design and revision of the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Review & Editing	YES
5516305	28720147	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6014064	29678672	A.N.	PLoS52	designed research|performed research|analyzed data|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
6014064	29678672	A.N.	PLoS52	designed research|performed research|analyzed data|wrote the paper	performed research	Performed the experiments	Investigation	YES
6014064	29678672	A.N.	PLoS52	designed research|performed research|analyzed data|wrote the paper	analyzed data	Analyzed the data	Formal analysis	YES
6014064	29678672	A.N.	PLoS52	designed research|performed research|analyzed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6014064	29678672	B.B.	PLoS52	designed research	designed research	Conceived and designed the experiments	Methodology	YES
6014064	29678672	B.J.-S.	PLoS52	designed research	designed research	Conceived and designed the experiments	Methodology	YES
6014064	29678672	B.K.	PLoS52	performed research|analyzed data	performed research	Performed the experiments	Investigation	YES
6014064	29678672	B.K.	PLoS52	performed research|analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
6014064	29678672	C.K.	PLoS52	performed research|analyzed data	performed research	Performed the experiments	Investigation	YES
6014064	29678672	C.K.	PLoS52	performed research|analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
6014064	29678672	D.T.	PLoS52	performed research|analyzed data	performed research	Performed the experiments	Investigation	YES
6014064	29678672	D.T.	PLoS52	performed research|analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
6014064	29678672	E.R.	PLoS52	designed research	designed research	Conceived and designed the experiments	Methodology	YES
6014064	29678672	K.G.S.	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
6014064	29678672	L.F.M.	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
6014064	29678672	L.K.	PLoS52	performed research|analyzed data	performed research	Performed the experiments	Investigation	YES
6014064	29678672	L.K.	PLoS52	performed research|analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
6014064	29678672	R.N.	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
6014064	29678672	R.V.	PLoS52	designed research|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
6014064	29678672	R.V.	PLoS52	designed research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6014064	29678672	U.S.	PLoS52	performed research|analyzed data|wrote the paper	performed research	Performed the experiments	Investigation	YES
6014064	29678672	U.S.	PLoS52	performed research|analyzed data|wrote the paper	analyzed data	Analyzed the data	Formal analysis	YES
6014064	29678672	U.S.	PLoS52	performed research|analyzed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6014064	29678672	V.R.-L.	PLoS52	performed research|analyzed data	performed research	Performed the experiments	Investigation	YES
6014064	29678672	V.R.-L.	PLoS52	performed research|analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
6014064	29678672	W.F.P.	PLoS52	designed research|analyzed data|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
6014064	29678672	W.F.P.	PLoS52	designed research|analyzed data|wrote the paper	analyzed data	Analyzed the data	Formal analysis	YES
6014064	29678672	W.F.P.	PLoS52	designed research|analyzed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5522885	28791029	BS	7	Substantial contributions to the conception/design work, the acquisition, analysis, and interpretation of data for the work; Drafting the work; Final approval of the version to be published; Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Substantial contributions to the conception/design work, the acquisition, analysis, and interpretation of data for the work; Drafting the work; Final approval of the version to be published; Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Data curation|Formal analysis|Investigation|Resources|Writing - Original Draft	YES
5522885	28791029	CL	7	Substantial contributions to the conception/design of the work; Revising the work critically for important intellectual content; Final approval of the version to be published; Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Substantial contributions to the conception/design of the work; Revising the work critically for important intellectual content; Final approval of the version to be published; Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Conceived and designed the experiments	Conceptualization	YES
5522885	28791029	DH	7	Substantial contributions to the conception/design of the work; Revising the work critically for important intellectual content; Final approval of the version to be published; Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Substantial contributions to the conception/design of the work; Revising the work critically for important intellectual content; Final approval of the version to be published; Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Conceived and designed the experiments	Conceptualization	YES
5522885	28791029	KK	7	Substantial contributions to the conception/design work, the acquisition, analysis, and interpretation of data for the work; Drafting the work; Final approval of the version to be published; Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Substantial contributions to the conception/design work, the acquisition, analysis, and interpretation of data for the work; Drafting the work; Final approval of the version to be published; Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Data curation|Formal analysis|Investigation|Resources|Writing - Original Draft	YES
4983137	27547398	Atsuhiro Kawashima	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
4983137	27547398	Hiroyuki Furukawa	2	assisted during the surgery	assisted during the surgery	Performed the experiments	Investigation	YES
4983137	27547398	Ichiro Ohnishi	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
4983137	27547398	Masato Kayahara	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
4983137	27547398	Nariatsu Sato	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
4983137	27547398	Satomi Kasashima	2	wrote draft of manuscript	wrote draft of manuscript	Wrote the paper	Writing - Original Draft	YES
4983137	27547398	Shigekazu Ohyama	2	assisted during the surgery	assisted during the surgery	Performed the experiments	Investigation	YES
4983137	27547398	Takahisa Yamaguchi	2	conducted the research and finishing manuscript	conducted the research and finishing manuscript	Performed the experiments	Investigation	YES
4405027	25875821	BdC	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405027	25875821	BdC	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405027	25875821	EB	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405027	25875821	EB	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405027	25875821	KL	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405027	25875821	KL	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405027	25875821	MF	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405027	25875821	MS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405027	25875821	MS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405027	25875821	PJ	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4405027	25875821	SR	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405027	25875821	SR	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405027	25875821	SR	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405027	25875821	TK	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405027	25875821	TK	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405027	25875821	TK	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4670836	26639116	KCES	2	conceived the manuscript and wrote the first draft	conceived the manuscript and wrote the first draft	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4670836	26639116	MBH	2	participated in the discussion of results and critically reviewed the final paper	participated in the discussion of results and critically reviewed the final paper	Wrote the paper	Writing - Review & Editing	YES
4670836	26639116	RSB	2	performed the literature review and finalized the manuscript	performed the literature review and finalized the manuscript	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
4670836	26639116	TFRW	2	participated in the discussion of results and critically reviewed the final paper	participated in the discussion of results and critically reviewed the final paper	Wrote the paper	Writing - Review & Editing	YES
4670836	26639116	TSB	2	participated in the discussion of results and critically reviewed the final paper	participated in the discussion of results and critically reviewed the final paper	Wrote the paper	Writing - Review & Editing	YES
4983144	27547399	CSN	2	performed the pathological review and review the final version	performed the pathological review and review the final version	Performed the experiments	Investigation	YES
4983144	27547399	GFAC	2	participated form the data review, data analysis and written version	participated form the data review, data analysis and written version	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4983144	27547399	MAAKF	2	participated form the study design, data analysis and review the final version	participated form the study design, data analysis and review the final version	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
4983144	27547399	MAM	2	performed the pathological review and review the final version	performed the pathological review and review the final version	Performed the experiments	Investigation	YES
4983144	27547399	MMB	2	participated form the study design, data analysis and review the final version	participated form the study design, data analysis and review the final version	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
4983144	27547399	RACV	2	participated from the study design, submission to ethics committee, cases selection, surgery, data analysis and written version	participated from the study design, submission to ethics committee, cases selection, surgery, data analysis and written version	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5249025	28105927	All	2	the coauthors read and approved the final version of the manuscript	the coauthors read and approved the final version of the manuscript	-	-	NO
5249025	28105927	DAR	2	designed, developed, maintained, adapted, and tuned the software for both sequence and data analysis	designed, developed, maintained, adapted, and tuned the software for both sequence and data analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Software	YES
5249025	28105927	EBS	2	compiled the data|conducted the cell culture experiments	compiled the data	-	Data curation	YES
5249025	28105927	EBS	2	compiled the data|conducted the cell culture experiments	conducted the cell culture experiments	Performed the experiments	Investigation	YES
5249025	28105927	EVK	2	conducted the cell culture experiments	conducted the cell culture experiments	Performed the experiments	Investigation	YES
5249025	28105927	IVC	2	interpreted the computer-based predictions and helped to draft the manuscript	interpreted the computer-based predictions and helped to draft the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5249025	28105927	LKS	2	coordinated the empirical research	coordinated the empirical research	-	Project administration	YES
5249025	28105927	MPP	2	wrote the manuscript and coordinated the computational research	wrote the manuscript and coordinated the computational research	Wrote the paper	Formal analysis|Project administration|Writing - Original Draft	YES
5249025	28105927	MYM	2	conducted the cell culture experiments	conducted the cell culture experiments	Performed the experiments	Investigation	YES
5249025	28105927	NAK	2	conceived of and supervised the study	conceived of and supervised the study	Conceived and designed the experiments	Conceptualization|Supervision	YES
5249025	28105927	NPB	2	conducted the cell culture experiments	conducted the cell culture experiments	Performed the experiments	Investigation	YES
5249025	28105927	OVA	2	conducted the cell culture experiments	conducted the cell culture experiments	Performed the experiments	Investigation	YES
5249025	28105927	PMP	2	designed and performed the sequence analysis	designed and performed the sequence analysis	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5249025	28105927	TVA	2	compiled the data	compiled the data	-	Data curation	YES
5530558	28747190	Both authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5530558	28747190	MK	2	was in charge of writing the review, whilst both authors approved the review	was in charge of writing the review, whilst both authors approved the review	Wrote the paper	Writing - Review & Editing	YES
5530558	28747190	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5537163	28480485	All	2	patients signed an informed consent to publication of anonymous and aggregate data derived from their medical records	patients signed an informed consent to publication of anonymous and aggregate data derived from their medical records	-	-	NO
5537163	28480485	All the authors	2	contributed to this paper by providing data and discussing the design and results of the study, and preparation of this report|read and approved the final manuscript	contributed to this paper by providing data and discussing the design and results of the study, and preparation of this report	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Methodology|Resources	YES
5537163	28480485	All the authors	2	contributed to this paper by providing data and discussing the design and results of the study, and preparation of this report|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5537163	28480485	Claire Slaney	2	for help with data collection	for help with data collection	Performed the experiments	Investigation	YES
5537163	28480485	Julie Garnham	2	for help with data collection	for help with data collection	Performed the experiments	Investigation	YES
5537163	28480485	Kathleen Cairns	2	for help with data collection	for help with data collection	Performed the experiments	Investigation	YES
5537163	28480485	Terry McCarvill	2	for help with data collection	for help with data collection	Performed the experiments	Investigation	YES
5537163	28480485	all authors	2	have no potential conflicts of interest to disclose, and their consulting relationships to industry are reported above	have no potential conflicts of interest to disclose, and their consulting relationships to industry are reported above	-	-	NO
5597153	28970440	All authors	2	have contributed to data evaluation of the study, and all authors have contributed to the manuscript	have contributed to data evaluation of the study, and all authors have contributed to the manuscript	-	-	NO
5597153	28970440	LJK	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4405191	25898267	MCS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405191	25898267	MCS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405191	25898267	MCS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405191	25898267	MCS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405191	25898267	RG	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4405191	25898267	RNM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405191	25898267	RNM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405191	25898267	RNM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405191	25898267	RNM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6020710	29784523	HT	2	contributed to reviewing and editing of the manuscript	contributed to reviewing and editing of the manuscript	Wrote the paper	Writing - Review & Editing	YES
6020710	29784523	KM	2	contributed to the letter layout, literature search, and writing of the manuscript	contributed to the letter layout, literature search, and writing of the manuscript	Wrote the paper	Formal analysis|Writing - Original Draft	YES
6020710	29784523	SN	2	contributed to reviewing and editing of the manuscript	contributed to reviewing and editing of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5523154	28791030	AV	2	assisted in the photosynthetic gas exchange and chlorophyll fluorescence measurements	assisted in the photosynthetic gas exchange and chlorophyll fluorescence measurements	Performed the experiments	Investigation	YES
5523154	28791030	AdC	2	planned, guided and performed experiments and wrote the paper	planned, guided and performed experiments and wrote the paper	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Supervision|Writing - Original Draft	YES
5523154	28791030	DP	2	performed the mass spectrometry identification of the proteins	performed the mass spectrometry identification of the proteins	Performed the experiments	Investigation	YES
5523154	28791030	JB	2	helped with the sugar content analysis	helped with the sugar content analysis	-	-	NO
5523154	28791030	JC	2	performed the mass spectrometry identification of the proteins	performed the mass spectrometry identification of the proteins	Performed the experiments	Investigation	YES
5523154	28791030	JL-N	2	undertook the free amino acid analysis	undertook the free amino acid analysis	Performed the experiments	Investigation	YES
5523154	28791030	JM	2	planned, guided and performed experiments and wrote the paper	planned, guided and performed experiments and wrote the paper	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Supervision|Writing - Original Draft	YES
5523154	28791030	KT	2	planned, performed experiments and wrote the paper	planned, performed experiments and wrote the paper	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
5523154	28791030	ML-G	2	helped with the sugar content analysis	helped with the sugar content analysis	-	-	NO
4983641	27551404	Keziban Ucar Karabulut	7	Study design, study execution, data collation	Study design, study execution, data collation	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4983641	27551404	Mehmet Uyar	7	Software design, software programming	Software design, software programming	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
4983641	27551404	Tomris Ugur Egercioglu	7	Data collation, data analysis, manuscript drafting, manuscript editing, manuscript submission, de facto correspondences	Data collation, data analysis, manuscript drafting, manuscript editing, manuscript submission, de facto correspondences	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
4983641	27551404	Yildiz Ucar	7	Software design, software programming, Study design, study execution	Software design, software programming, Study design, study execution	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Software	YES
4670837	26639115	All authors	2	contributed to writing and review, and all read and approved the final version	contributed to writing and review, and all read and approved the final version	Wrote the paper	Writing - Review & Editing	YES
4670837	26639115	LC	2	conceptualized the paper	conceptualized the paper	Conceived and designed the experiments	Conceptualization	YES
4670837	26639115	RH	2	conceptualized the paper	conceptualized the paper	Conceived and designed the experiments	Conceptualization	YES
4983645	27551403	ADNANE	2	were involved in critical review and making corrections to the manuscript	were involved in critical review and making corrections to the manuscript	Wrote the paper	Writing - Review & Editing	YES
4983645	27551403	TAZI	2	was involved in the case writing and data collection for the case report	was involved in the case writing and data collection for the case report	Performed the experiments|Wrote the paper	Investigation	YES
4475764	26167481	Fang Ye	2	contributed equally to this work	contributed equally to this work	-	-	NO
4475764	26167481	Qi Lu	2	contributed equally to this work	contributed equally to this work	-	-	NO
5249031	28105928	AFC	2	contributed in performing the computational analysis, reviewed and edited the manuscript	contributed in performing the computational analysis, reviewed and edited the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
5249031	28105928	EQGS	2	participated in the activities of isolation, identification and characterization of the peptide using proteomics tools and performed antimicrobial assays	participated in the activities of isolation, identification and characterization of the peptide using proteomics tools and performed antimicrobial assays	Performed the experiments	Investigation	YES
5249031	28105928	GRF	2	contributed in performing the computational analyzes	contributed in performing the computational analyzes	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5249031	28105928	HOAS	2	participated in the activities of isolation, identification and characterization of the peptide using proteomics tools	participated in the activities of isolation, identification and characterization of the peptide using proteomics tools	Performed the experiments	Investigation	YES
5249031	28105928	MCBP	2	conceived the idea, designed and supervised all activities of work, performed the computational analyzes, and drafted, reviewed and edited the manuscript	conceived the idea, designed and supervised all activities of work, performed the computational analyzes, and drafted, reviewed and edited the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
5249031	28105928	MJMJ	2	participated in the activities of isolation, identification and characterization of the peptide using proteomics tools	participated in the activities of isolation, identification and characterization of the peptide using proteomics tools	Performed the experiments	Investigation	YES
5249031	28105928	MOB	2	participated in the activities of isolation, identification and characterization of the peptide using proteomics tools	participated in the activities of isolation, identification and characterization of the peptide using proteomics tools	Performed the experiments	Investigation	YES
5249031	28105928	MVP	2	conducted and advised analyzes of automatic peptide sequencing and advised mass spectrometry analyzes	conducted and advised analyzes of automatic peptide sequencing and advised mass spectrometry analyzes	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5249031	28105928	PDG	2	cultivated plants, planned and participated in all activities of isolation, identification and characterization of the peptide using proteomics tools, performed antimicrobial assays, and drafted and reviewed the manuscript	cultivated plants, planned and participated in all activities of isolation, identification and characterization of the peptide using proteomics tools, performed antimicrobial assays, and drafted and reviewed the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5249031	28105928	PPF	2	participated in the activities of isolation, identification and characterization of the peptide using proteomics tools	participated in the activities of isolation, identification and characterization of the peptide using proteomics tools	Performed the experiments	Investigation	YES
5249031	28105928	PRGP	2	planned planting and cultivated plants, led discussions on the involvement of peptides in plant defense, and reviewed and edited the manuscript	planned planting and cultivated plants, led discussions on the involvement of peptides in plant defense, and reviewed and edited the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Review & Editing	YES
5249031	28105928	SVAC	2	contributed in performing the computational analysis, reviewed and edited the manuscript	contributed in performing the computational analysis, reviewed and edited the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
5597154	28970441	Helena Huhtala	2	commented the manuscript	commented the manuscript	-	-	NO
5597154	28970441	Pia Vuorela	2	commented the manuscript	commented the manuscript	-	-	NO
5531022	28750647	All authors	2	read and approved the manuscript	read and approved the manuscript	-	-	NO
5531022	28750647	CM	2	were involved in sampling and performing experiments	were involved in sampling and performing experiments	Performed the experiments	Investigation	YES
5531022	28750647	DMT	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5531022	28750647	DR	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5531022	28750647	EME	2	were involved in sampling and performing experiments|was supported by the research and publications committee of the university of venda	were involved in sampling and performing experiments	Performed the experiments	Investigation	YES
5531022	28750647	EME	2	were involved in sampling and performing experiments|was supported by the research and publications committee of the university of venda	was supported by the research and publications committee of the university of venda	-	-	NO
5531022	28750647	KMG	2	were involved in sampling and performing experiments	were involved in sampling and performing experiments	Performed the experiments	Investigation	YES
5531022	28750647	LM	2	were involved in sampling and performing experiments	were involved in sampling and performing experiments	Performed the experiments	Investigation	YES
5531022	28750647	MLH	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5531022	28750647	PB	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5531022	28750647	PJ	2	interpreted the data and participated in writing the manuscript	interpreted the data and participated in writing the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5531022	28750647	POB	2	received grant support from the south african medical research council and the national research foundation	received grant support from the south african medical research council and the national research foundation	-	Funding acquisition	YES
5531022	28750647	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5545079	28480484	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5545079	28480484	DG	2	has nothing to declare	has nothing to declare	-	-	NO
5545079	28480484	LB	2	has nothing to declare	has nothing to declare	-	-	NO
5545079	28480484	NAC	2	related compounds for psychiatric indications, which, while assigned to the mental health research institute, could lead to personal remuneration upon a commercialization event	related compounds for psychiatric indications, which, while assigned to the mental health research institute, could lead to personal remuneration upon a commercialization event	Performed the experiments	Investigation	YES
5545079	28480484	NIH	2	the stanley medical foundation, the klingenstein third generation foundation, and the spectrum child health research institute	the stanley medical foundation, the klingenstein third generation foundation, and the spectrum child health research institute	-	-	NO
5545079	28480484	VC	2	was responsible for conception and design as well as initial drafting of the manuscript	was responsible for conception and design as well as initial drafting of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
6020711	29793878	All authors	1	Manuscript writing|Final approval of manuscript|Accountable for all aspects of the work	Manuscript writing	Wrote the paper	Writing - Original Draft	YES
6020711	29793878	All authors	1	Manuscript writing|Final approval of manuscript|Accountable for all aspects of the work	Final approval of manuscript	-	-	NO
6020711	29793878	All authors	1	Manuscript writing|Final approval of manuscript|Accountable for all aspects of the work	Accountable for all aspects of the work	-	-	NO
6020711	29793878	CX	1	Assess and assembly of data	Assess and assembly of data	-	-	NO
6020711	29793878	GQW	1	Concept and design|Assess and assembly of data	Concept and design	Conceived and designed the experiments	Conceptualization	YES
6020711	29793878	GQW	1	Concept and design|Assess and assembly of data	Assess and assembly of data	-	-	NO
6020711	29793878	JC	1	Concept and design	Concept and design	Conceived and designed the experiments	Conceptualization	YES
6020711	29793878	JG	1	Data analysis and interpretation	Data analysis and interpretation	Analyzed the data	Formal analysis	YES
6020711	29793878	ND	1	Data analysis and interpretation	Data analysis and interpretation	Analyzed the data	Formal analysis	YES
6020711	29793878	SLC	1	Concept and design	Concept and design	Conceived and designed the experiments	Conceptualization	YES
6020711	29793878	TH	1	Data analysis and interpretation	Data analysis and interpretation	Analyzed the data	Formal analysis	YES
6020711	29793878	TY	1	Assess and assembly of data|Assess and assembly of data	Assess and assembly of data	-	-	NO
6020711	29793878	TY	1	Assess and assembly of data|Assess and assembly of data	Assess and assembly of data	-	-	NO
6020711	29793878	WJX	1	Data analysis and interpretation	Data analysis and interpretation	Analyzed the data	Formal analysis	YES
6020711	29793878	WW	1	Assess and assembly of data	Assess and assembly of data	-	-	NO
6020711	29793878	XM	1	Assess and assembly of data	Assess and assembly of data	-	-	NO
6020711	29793878	YC	1	Assess and assembly of data	Assess and assembly of data	-	-	NO
5524734	28791035	AR	2	were involved in both data acquisition and interpretation	were involved in both data acquisition and interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5524734	28791035	All the authors	2	contribute in drafting and reviewing the article|approved the final version of this text	contribute in drafting and reviewing the article	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5524734	28791035	All the authors	2	contribute in drafting and reviewing the article|approved the final version of this text	approved the final version of this text	-	-	NO
5524734	28791035	CL	2	took part in the experimental work|were involved in both data acquisition and interpretation	took part in the experimental work	Performed the experiments	Investigation	YES
5524734	28791035	CL	2	took part in the experimental work|were involved in both data acquisition and interpretation	were involved in both data acquisition and interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5524734	28791035	JB	2	contributed to the project design|were involved in both data acquisition and interpretation	contributed to the project design	Conceived and designed the experiments	Methodology	YES
5524734	28791035	JB	2	contributed to the project design|were involved in both data acquisition and interpretation	were involved in both data acquisition and interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5524734	28791035	JG	2	contributed to the project design|took part in the experimental work|performed the statistical and bioinformatic analyses|were involved in both data acquisition and interpretation|wrote the manuscript	contributed to the project design	Conceived and designed the experiments	Methodology	YES
5524734	28791035	JG	2	contributed to the project design|took part in the experimental work|performed the statistical and bioinformatic analyses|were involved in both data acquisition and interpretation|wrote the manuscript	took part in the experimental work	Performed the experiments	Investigation	YES
5524734	28791035	JG	2	contributed to the project design|took part in the experimental work|performed the statistical and bioinformatic analyses|were involved in both data acquisition and interpretation|wrote the manuscript	performed the statistical and bioinformatic analyses	Analyzed the data	Formal analysis	YES
5524734	28791035	JG	2	contributed to the project design|took part in the experimental work|performed the statistical and bioinformatic analyses|were involved in both data acquisition and interpretation|wrote the manuscript	were involved in both data acquisition and interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5524734	28791035	JG	2	contributed to the project design|took part in the experimental work|performed the statistical and bioinformatic analyses|were involved in both data acquisition and interpretation|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5524734	28791035	JM	2	contributed to the project design	contributed to the project design	Conceived and designed the experiments	Methodology	YES
5524734	28791035	LT	2	contributed to the project design|were involved in both data acquisition and interpretation	contributed to the project design	Conceived and designed the experiments	Methodology	YES
5524734	28791035	LT	2	contributed to the project design|were involved in both data acquisition and interpretation	were involved in both data acquisition and interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5524734	28791035	NI	2	contributed to the project design|took part in the experimental work|were involved in both data acquisition and interpretation	contributed to the project design	Conceived and designed the experiments	Methodology	YES
5524734	28791035	NI	2	contributed to the project design|took part in the experimental work|were involved in both data acquisition and interpretation	took part in the experimental work	Performed the experiments	Investigation	YES
5524734	28791035	NI	2	contributed to the project design|took part in the experimental work|were involved in both data acquisition and interpretation	were involved in both data acquisition and interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5524734	28791035	PL	2	performed the statistical and bioinformatic analyses	performed the statistical and bioinformatic analyses	Analyzed the data	Formal analysis	YES
5524734	28791035	The authors	2	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	Performed the experiments	Investigation	YES
4405192	25898185	AH	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405192	25898185	AH	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405192	25898185	AH	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405192	25898185	BH	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405192	25898185	BH	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405192	25898185	DR	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405192	25898185	JG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405192	25898185	JG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405192	25898185	JG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4475765	26167474	Luca Agnifili	2	equally contributed to this work and share primary authorship	equally contributed to this work and share primary authorship	Wrote the paper	Writing - Original Draft	YES
4475765	26167474	Rodolfo Mastropasqua	2	equally contributed to this work and share primary authorship	equally contributed to this work and share primary authorship	Wrote the paper	Writing - Original Draft	YES
4670838	26639120	All authors	5	contributed equally to the development and review of this Manuscript	contributed equally to the development and review of this Manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4990566	27570621	AE	2	was engaged in patients care after the surgery	was engaged in patients care after the surgery	Performed the experiments	Investigation	YES
4990566	27570621	CE	2	supervised the s care in his hospital coarse including surgery under the|also reviewed the final manuscript	supervised the s care in his hospital coarse including surgery under the	Performed the experiments	Investigation|Supervision	YES
4990566	27570621	CE	2	supervised the s care in his hospital coarse including surgery under the|also reviewed the final manuscript	also reviewed the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4990566	27570621	CG	2	supervised the s care in his hospital coarse including surgery under the|reviewed the final manuscript	supervised the s care in his hospital coarse including surgery under the	Performed the experiments	Investigation|Supervision	YES
4990566	27570621	CG	2	supervised the s care in his hospital coarse including surgery under the|reviewed the final manuscript	reviewed the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4990566	27570621	DA	2	contributed to initial draft and interpretation of data and was engaged in patients care in his hospital coarse including surgery under the	contributed to initial draft and interpretation of data and was engaged in patients care in his hospital coarse including surgery under the	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft	YES
4990566	27570621	TA	2	contributed to study concept/design, interpretation, review of manuscript and its final submission	contributed to study concept/design, interpretation, review of manuscript and its final submission	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Review & Editing	YES
4990566	27570621	VM	2	helped with data collection, interpretation and writing of the paper	helped with data collection, interpretation and writing of the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4990566	27570621	XS	2	helped with data collection, interpretation and writing of the paper	helped with data collection, interpretation and writing of the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5597155	28970442	J.H.	2	conceived the project|have all contributed to the writing and review of the manuscript	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5597155	28970442	J.H.	2	conceived the project|have all contributed to the writing and review of the manuscript	have all contributed to the writing and review of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5597155	28970442	J.J.	2	undertook the literature review|have all contributed to the writing and review of the manuscript	undertook the literature review	Performed the experiments	Formal analysis|Investigation	YES
5597155	28970442	J.J.	2	undertook the literature review|have all contributed to the writing and review of the manuscript	have all contributed to the writing and review of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5597155	28970442	T.F.S.	2	have all contributed to the writing and review of the manuscript	have all contributed to the writing and review of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4670839	26639119	EJA	2	each contributed to the content, writing and editing of this manuscript	each contributed to the content, writing and editing of this manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4670839	26639119	SS	2	each contributed to the content, writing and editing of this manuscript	each contributed to the content, writing and editing of this manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4477049	26180781	All authors	2	read and approved the final paper	read and approved the final paper	-	-	NO
4477049	26180781	Barbara Zavan	2	conceived the study and participated in its design and coordination	conceived the study and participated in its design and coordination	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
4477049	26180781	Chiara Gardin	2	carried out the biological and molecular studies	carried out the biological and molecular studies	Performed the experiments	Investigation	YES
4477049	26180781	Ilaria Tocco	2	helped to draft the paper	helped to draft the paper	Wrote the paper	Writing - Original Draft	YES
4477049	26180781	Letizia Ferroni	2	carried out the biological and molecular studies|contributed equally to this work	carried out the biological and molecular studies	Performed the experiments	Investigation	YES
4477049	26180781	Letizia Ferroni	2	carried out the biological and molecular studies|contributed equally to this work	contributed equally to this work	-	-	NO
4477049	26180781	Maria Elena Falomo	2	partook in samples collection and data analyses|conceived the study and participated in its design and coordination|contributed equally to this work	partook in samples collection and data analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4477049	26180781	Maria Elena Falomo	2	partook in samples collection and data analyses|conceived the study and participated in its design and coordination|contributed equally to this work	conceived the study and participated in its design and coordination	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
4477049	26180781	Maria Elena Falomo	2	partook in samples collection and data analyses|conceived the study and participated in its design and coordination|contributed equally to this work	contributed equally to this work	-	-	NO
4405199	25898287	BJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405199	25898287	BJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405199	25898287	BJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405199	25898287	BJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405199	25898287	BJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405199	25898287	DA	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405199	25898287	DA	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405199	25898287	DA	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405199	25898287	JC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405199	25898287	JC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405199	25898287	JC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405199	25898287	JC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405199	25898287	JD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405199	25898287	JD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405199	25898287	JD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405199	25898287	JD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405199	25898287	JD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405199	25898287	RW	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405199	25898287	RW	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405199	25898287	RW	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5524738	28791028	GS	5	conceived and drafted the manuscript	conceived and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5524738	28791028	KY	5	provided revisions to the MS	provided revisions to the MS	Wrote the paper	Writing - Review & Editing	YES
5524738	28791028	RC	5	provided revisions to the MS	provided revisions to the MS	Wrote the paper	Writing - Review & Editing	YES
5524738	28791028	XW	5	provided revisions to the MS	provided revisions to the MS	Wrote the paper	Writing - Review & Editing	YES
5545092	28779758	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5545092	28779758	CM	2	gave key contributions to the interpretation of data	gave key contributions to the interpretation of data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5545092	28779758	EF	2	collected the data	collected the data	Performed the experiments	Investigation	YES
5545092	28779758	FDB	2	gave key contributions to the interpretation of data	gave key contributions to the interpretation of data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5545092	28779758	GD	2	designed the study|collected the data|wrote the first draft of the paper|gave key contributions to the interpretation of data|formatted the manuscript for publication	designed the study	Conceived and designed the experiments	Methodology	YES
5545092	28779758	GD	2	designed the study|collected the data|wrote the first draft of the paper|gave key contributions to the interpretation of data|formatted the manuscript for publication	collected the data	Performed the experiments	Investigation	YES
5545092	28779758	GD	2	designed the study|collected the data|wrote the first draft of the paper|gave key contributions to the interpretation of data|formatted the manuscript for publication	wrote the first draft of the paper	Wrote the paper	Writing - Original Draft	YES
5545092	28779758	GD	2	designed the study|collected the data|wrote the first draft of the paper|gave key contributions to the interpretation of data|formatted the manuscript for publication	gave key contributions to the interpretation of data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5545092	28779758	GD	2	designed the study|collected the data|wrote the first draft of the paper|gave key contributions to the interpretation of data|formatted the manuscript for publication	formatted the manuscript for publication	-	-	NO
5545092	28779758	GG	2	designed the study|wrote the first draft of the paper|gave key contributions to the interpretation of data	designed the study	Conceived and designed the experiments	Methodology	YES
5545092	28779758	GG	2	designed the study|wrote the first draft of the paper|gave key contributions to the interpretation of data	wrote the first draft of the paper	Wrote the paper	Writing - Original Draft	YES
5545092	28779758	GG	2	designed the study|wrote the first draft of the paper|gave key contributions to the interpretation of data	gave key contributions to the interpretation of data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5545092	28779758	GT	2	collected the data	collected the data	Performed the experiments	Investigation	YES
5545092	28779758	MC	2	collected the data	collected the data	Performed the experiments	Investigation	YES
5545092	28779758	RB	2	collected the data	collected the data	Performed the experiments	Investigation	YES
5545092	28779758	SZ	2	performed the statistical analysis|wrote the first draft of the paper|gave key contributions to the interpretation of data	performed the statistical analysis	Analyzed the data	Formal analysis	YES
5545092	28779758	SZ	2	performed the statistical analysis|wrote the first draft of the paper|gave key contributions to the interpretation of data	wrote the first draft of the paper	Wrote the paper	Writing - Original Draft	YES
5545092	28779758	SZ	2	performed the statistical analysis|wrote the first draft of the paper|gave key contributions to the interpretation of data	gave key contributions to the interpretation of data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5545092	28779758	TDB	2	gave key contributions to the interpretation of data	gave key contributions to the interpretation of data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5545092	28779758	VS	2	collected the data	collected the data	Performed the experiments	Investigation	YES
5554118	28480483	All authors	2	revised the draft manuscript|read and approved the final manuscript	revised the draft manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5554118	28480483	All authors	2	revised the draft manuscript|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5554118	28480483	DRB	2	devised the study|performed the literature review|performed the data analyses|wrote the first draft of the manuscript	devised the study	Conceived and designed the experiments	Conceptualization	YES
5554118	28480483	DRB	2	devised the study|performed the literature review|performed the data analyses|wrote the first draft of the manuscript	performed the literature review	Performed the experiments	Formal analysis|Investigation	YES
5554118	28480483	DRB	2	devised the study|performed the literature review|performed the data analyses|wrote the first draft of the manuscript	performed the data analyses	Analyzed the data	Formal analysis	YES
5554118	28480483	DRB	2	devised the study|performed the literature review|performed the data analyses|wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
5554118	28480483	HK	2	constructed the electronic database|performed the data analyses	constructed the electronic database	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5554118	28480483	HK	2	constructed the electronic database|performed the data analyses	performed the data analyses	Analyzed the data	Formal analysis	YES
5554118	28480483	Human Subjects	2	patients provided verbal and written informed consent prior to participation	patients provided verbal and written informed consent prior to participation	Wrote the paper	Writing - Original Draft	YES
5554118	28480483	KCG	2	performed the literature review|constructed the electronic database|performed the data analyses	performed the literature review	Performed the experiments	Formal analysis|Investigation	YES
5554118	28480483	KCG	2	performed the literature review|constructed the electronic database|performed the data analyses	constructed the electronic database	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5554118	28480483	KCG	2	performed the literature review|constructed the electronic database|performed the data analyses	performed the data analyses	Analyzed the data	Formal analysis	YES
5554118	28480483	LDY	2	constructed the electronic database|performed the data analyses	constructed the electronic database	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5554118	28480483	LDY	2	constructed the electronic database|performed the data analyses	performed the data analyses	Analyzed the data	Formal analysis	YES
5554118	28480483	NLR	2	devised the study	devised the study	Conceived and designed the experiments	Conceptualization	YES
5554118	28480483	PWW	2	assessed and treated the patients|performed the data analyses	assessed and treated the patients	Performed the experiments	Investigation	YES
5554118	28480483	PWW	2	assessed and treated the patients|performed the data analyses	performed the data analyses	Analyzed the data	Formal analysis	YES
5554118	28480483	Research Year Grants	2	from inje university, the pearlstein family foundation, the mitchell foundation, and the holland foundation	from inje university, the pearlstein family foundation, the mitchell foundation, and the holland foundation	-	-	NO
5554118	28480483	SM	2	assessed and treated the patients|performed the data analyses	assessed and treated the patients	Performed the experiments	Investigation	YES
5554118	28480483	SM	2	assessed and treated the patients|performed the data analyses	performed the data analyses	Analyzed the data	Formal analysis	YES
5554118	28480483	SS	2	performed the literature review|constructed the electronic database|performed the data analyses	performed the literature review	Performed the experiments	Formal analysis|Investigation	YES
5554118	28480483	SS	2	performed the literature review|constructed the electronic database|performed the data analyses	constructed the electronic database	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5554118	28480483	SS	2	performed the literature review|constructed the electronic database|performed the data analyses	performed the data analyses	Analyzed the data	Formal analysis	YES
5554118	28480483	TAK	2	devised the study|assessed and treated the patients	devised the study	Conceived and designed the experiments	Conceptualization	YES
5554118	28480483	TAK	2	devised the study|assessed and treated the patients	assessed and treated the patients	Performed the experiments	Investigation	YES
6020856	29887330	AT	2	assisted with the performed most of the experiments with	assisted with the performed most of the experiments with	Performed the experiments	Investigation	YES
6020856	29887330	ES	2	assisted with the performed most of the experiments with	assisted with the performed most of the experiments with	Performed the experiments	Investigation	YES
6020856	29887330	HPNL	2	performed the in vivo atp analysis	performed the in vivo atp analysis	Performed the experiments	Investigation	YES
6020856	29887330	KF	2	assisted with the performed most of the experiments with	assisted with the performed most of the experiments with	Performed the experiments	Investigation	YES
6020856	29887330	KS	2	assisted with the performed most of the experiments with	assisted with the performed most of the experiments with	Performed the experiments	Investigation	YES
6020856	29887330	MH	2	generated vnut-ko mice	generated vnut-ko mice	Performed the experiments	Investigation	YES
6020856	29887330	MK	2	performed most of the experiments with|analyzed the data and wrote the paper	performed most of the experiments with	Performed the experiments	Investigation	YES
6020856	29887330	MK	2	performed most of the experiments with|analyzed the data and wrote the paper	analyzed the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6020856	29887330	SK	2	designed the research|analyzed the data and wrote the paper	designed the research	Conceived and designed the experiments	Methodology	YES
6020856	29887330	SK	2	designed the research|analyzed the data and wrote the paper	analyzed the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6020856	29887330	SY	2	assisted with the performed most of the experiments with	assisted with the performed most of the experiments with	Performed the experiments	Investigation	YES
6020856	29887330	YH	2	performed the in vivo atp analysis	performed the in vivo atp analysis	Performed the experiments	Investigation	YES
6020856	29887330	YM	2	generated vnut-ko mice	generated vnut-ko mice	Performed the experiments	Investigation	YES
5249038	28105924	AM	2	has made substantial contributions to conception and design of the study and participated in interpretation of data	has made substantial contributions to conception and design of the study and participated in interpretation of data	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Methodology|Resources	YES
5249038	28105924	LF	2	performed quantitative real time pcr, participated in interpretation of data, and helped to draft the manuscript	performed quantitative real time pcr, participated in interpretation of data, and helped to draft the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5249038	28105924	LK	2	performed quantitative real time pcr, participated in interpretation of data, and helped to draft the manuscript	performed quantitative real time pcr, participated in interpretation of data, and helped to draft the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5249038	28105924	NE	2	has made substantial contribution to bioinformatics analysis	has made substantial contribution to bioinformatics analysis	-	Formal analysis	YES
5249038	28105924	OR	2	participated in interpretation of data and drafted the manuscript	participated in interpretation of data and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5249038	28105924	VE	2	has made substantial contributions to conception and use of multivariate statistical analysis	has made substantial contributions to conception and use of multivariate statistical analysis	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
5249038	28105924	YuA	2	performed the functional analysis of degs	performed the functional analysis of degs	Performed the experiments	Investigation	YES
4990637	27570620	AB	7	data collection, data analysis	data collection, data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4990637	27570620	CS	7	study design, data analysis, writing	study design, data analysis, writing	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology	YES
4405200	25897665	EJK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405200	25897665	EJK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405200	25897665	EJK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405200	25897665	EJK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405200	25897665	IVD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405200	25897665	IVD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405200	25897665	IVD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405200	25897665	LK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405200	25897665	LK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4405200	25897665	LK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4405200	25897665	RDC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405200	25897665	RDC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405200	25897665	RDC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405200	25897665	TKL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5524744	28791031	GC	2	provided the rice samples and also performed experiments	provided the rice samples and also performed experiments	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5524744	28791031	HF	2	designed the research, performed the experiments, analyzed the data and wrote the manuscript	designed the research, performed the experiments, analyzed the data and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5524744	28791031	LX	2	supervised the project, designed the research, and wrote the manuscript	supervised the project, designed the research, and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Original Draft	YES
5524744	28791031	QL	2	supervised the project, designed the research, and wrote the manuscript	supervised the project, designed the research, and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Original Draft	YES
5524744	28791031	The authors	2	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	Performed the experiments	Investigation	YES
5524744	28791031	WY	2	designed the research, performed the experiments, analyzed the data and wrote the manuscript	designed the research, performed the experiments, analyzed the data and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5597157	28970444	C.P.B.	4	reviewed and discussed by|reviewed and approved by	reviewed and discussed by	-	-	NO
5597157	28970444	C.P.B.	4	reviewed and discussed by|reviewed and approved by	reviewed and approved by	-	-	NO
5597157	28970444	C.R.H.	4	interviews were transcribed by|codes and themes were developed by|the manuscript was prepared by	interviews were transcribed by	Performed the experiments	Investigation	YES
5597157	28970444	C.R.H.	4	interviews were transcribed by|codes and themes were developed by|the manuscript was prepared by	codes and themes were developed by	-	-	NO
5597157	28970444	C.R.H.	4	interviews were transcribed by|codes and themes were developed by|the manuscript was prepared by	the manuscript was prepared by	Wrote the paper	Writing - Original Draft	YES
5597157	28970444	E.K.W.	4	codes and themes were developed by|reviewed and approved by	codes and themes were developed by	-	-	NO
5597157	28970444	E.K.W.	4	codes and themes were developed by|reviewed and approved by	reviewed and approved by	-	-	NO
5597157	28970444	L.J.S.	4	reviewed and discussed by|reviewed and approved by	reviewed and discussed by	-	-	NO
5597157	28970444	L.J.S.	4	reviewed and discussed by|reviewed and approved by	reviewed and approved by	-	-	NO
4670840	26639111	AA	2	revised the draft, assisted in literature search and ensured consistency and accuracy of the manuscript contents	revised the draft, assisted in literature search and ensured consistency and accuracy of the manuscript contents	Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
4670840	26639111	All co-authors	2	contributed equally to the conceptualization and design of this article	contributed equally to the conceptualization and design of this article	Conceived and designed the experiments	Conceptualization	YES
4670840	26639111	CL	2	revised the draft, assisted in literature search and ensured consistency and accuracy of the manuscript contents	revised the draft, assisted in literature search and ensured consistency and accuracy of the manuscript contents	Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
4670840	26639111	DC	2	generated the first draft of the manuscript, coordinated inputs and comments and revised and submitted the article for peer review	generated the first draft of the manuscript, coordinated inputs and comments and revised and submitted the article for peer review	Performed the experiments|Wrote the paper	Investigation|Project administration|Writing - Original Draft|Writing - Review & Editing	YES
4670840	26639111	MY	2	revised the draft, assisted in literature search and ensured consistency and accuracy of the manuscript contents	revised the draft, assisted in literature search and ensured consistency and accuracy of the manuscript contents	Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
4670840	26639111	NS	2	revised the draft, assisted in literature search and ensured consistency and accuracy of the manuscript contents	revised the draft, assisted in literature search and ensured consistency and accuracy of the manuscript contents	Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
4670840	26639111	RL	2	revised the draft, assisted in literature search and ensured consistency and accuracy of the manuscript contents	revised the draft, assisted in literature search and ensured consistency and accuracy of the manuscript contents	Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
4670840	26639111	SE	2	revised the draft, assisted in literature search and ensured consistency and accuracy of the manuscript contents	revised the draft, assisted in literature search and ensured consistency and accuracy of the manuscript contents	Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
4670840	26639111	SK	2	revised the draft, assisted in literature search and ensured consistency and accuracy of the manuscript contents	revised the draft, assisted in literature search and ensured consistency and accuracy of the manuscript contents	Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
4995439	27594996	Arianeb Mehrabi	7	data collection, discussion	data collection, discussion	Performed the experiments	Investigation	YES
4995439	27594996	Carolin Mogler	7	pathology, proof reading	pathology, proof reading	Performed the experiments	Investigation	YES
4995439	27594996	Ingo Alldinger	7	data collection, manuscript	data collection, manuscript	Performed the experiments	Investigation	YES
4995439	27594996	Karl Heinz Weiss	7	data collection, proof reading	data collection, proof reading	Performed the experiments	Investigation	YES
4995439	27594996	Katrin Hoffmann	7	data collection, proof reading	data collection, proof reading	Performed the experiments	Investigation	YES
4995439	27594996	Markus W. Buchler	7	proof reading	proof reading	-	-	NO
4995439	27594996	Peter Schemmer	7	data collection, proof reading	data collection, proof reading	Performed the experiments	Investigation	YES
4405201	25898211	JVS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Supervised the project	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405201	25898211	JVS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Supervised the project	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405201	25898211	JVS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Supervised the project	Supervised the project	-	Supervision	YES
4405201	25898211	MA	PLoS5	Contributed reagents/materials/analysis tools|Supervised the project	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405201	25898211	MA	PLoS5	Contributed reagents/materials/analysis tools|Supervised the project	Supervised the project	-	Supervision	YES
4405201	25898211	MN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405201	25898211	MN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405201	25898211	MN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405201	25898211	MN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405201	25898211	NMS	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405201	25898211	SA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Supervised the project	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405201	25898211	SA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Supervised the project	Analyzed the data	Analyzed the data	Formal analysis	YES
4405201	25898211	SA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Supervised the project	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405201	25898211	SA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Supervised the project	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405201	25898211	SA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Supervised the project	Supervised the project	-	Supervision	YES
4405201	25898211	TV	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405201	25898211	TV	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5249040	28105925	AB	2	wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
5249040	28105925	BioM	2	for several thematic post-conference issues	for several thematic post-conference issues	-	-	NO
5249040	28105925	NK	2	edited the text	edited the text	Wrote the paper	Writing - Review & Editing	YES
5249040	28105925	RH	2	edited the text	edited the text	Wrote the paper	Writing - Review & Editing	YES
5249040	28105925	YO	2	wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
4670841	26639117	AO	2	contributed to further drafts	contributed to further drafts	Wrote the paper	Writing - Original Draft	YES
4670841	26639117	EC	2	contributed to further drafts	contributed to further drafts	Wrote the paper	Writing - Original Draft	YES
4670841	26639117	FP	2	contributed to further drafts	contributed to further drafts	Wrote the paper	Writing - Original Draft	YES
4670841	26639117	JL	2	wrote the first draft	wrote the first draft	Wrote the paper	Writing - Original Draft	YES
4670841	26639117	ML	2	wrote the first draft	wrote the first draft	Wrote the paper	Writing - Original Draft	YES
4670841	26639117	MP	2	wrote the first draft	wrote the first draft	Wrote the paper	Writing - Original Draft	YES
4670841	26639117	NF	2	contributed to further drafts	contributed to further drafts	Wrote the paper	Writing - Original Draft	YES
4670841	26639117	NS	2	contributed to further drafts	contributed to further drafts	Wrote the paper	Writing - Original Draft	YES
4670841	26639117	SE	2	contributed to further drafts	contributed to further drafts	Wrote the paper	Writing - Original Draft	YES
5580224	28859681	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5580224	28859681	BK	2	obtained the clinical data under the	obtained the clinical data under the	Performed the experiments	Investigation	YES
5580224	28859681	IA	2	analysed cmv antibodies	analysed cmv antibodies	Performed the experiments	Investigation	YES
5580224	28859681	IPW	2	directed bk obtained the clinical data under the	directed bk obtained the clinical data under the	Performed the experiments	Investigation|Supervision	YES
5580224	28859681	PP	2	directed the project	directed the project	-	Supervision	YES
5580224	28859681	RE	2	analysed cmv antibodies	analysed cmv antibodies	Performed the experiments	Investigation	YES
5580224	28859681	RR	2	assisted with data management	assisted with data management	Analyzed the data	Data curation	YES
5524766	28791041	CG	PLoS52	analyzed the data|helped to draft the manuscript and revise the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5524766	28791041	CG	PLoS52	analyzed the data|helped to draft the manuscript and revise the manuscript	helped to draft the manuscript and revise the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5524766	28791041	CJ	PLoS52	carried out the experiments|analyzed the data|wrote the manuscript	carried out the experiments	Performed the experiments	Investigation	YES
5524766	28791041	CJ	PLoS52	carried out the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5524766	28791041	CJ	PLoS52	carried out the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5524766	28791041	DL	PLoS52	carried out the experiments|helped to draft the manuscript and revise the manuscript	carried out the experiments	Performed the experiments	Investigation	YES
5524766	28791041	DL	PLoS52	carried out the experiments|helped to draft the manuscript and revise the manuscript	helped to draft the manuscript and revise the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5524766	28791041	JG	PLoS52	assisted with doing the experiments	assisted with doing the experiments	Performed the experiments	Investigation	YES
5524766	28791041	JH	PLoS52	helped to draft the manuscript and revise the manuscript	helped to draft the manuscript and revise the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5524766	28791041	JW	PLoS52	assisted with doing the experiments	assisted with doing the experiments	Performed the experiments	Investigation	YES
5524766	28791041	KL	PLoS52	assisted with doing the experiments	assisted with doing the experiments	Performed the experiments	Investigation	YES
5524766	28791041	MC	PLoS52	conceived and designed the experiments|wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5524766	28791041	MC	PLoS52	conceived and designed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5524766	28791041	SD	PLoS52	assisted with doing the experiments	assisted with doing the experiments	Performed the experiments	Investigation	YES
5524766	28791041	SQ	PLoS52	assisted with doing the experiments	assisted with doing the experiments	Performed the experiments	Investigation	YES
5524766	28791041	ZL	PLoS52	assisted with doing the experiments	assisted with doing the experiments	Performed the experiments	Investigation	YES
5563503	28480486	AT	2	designed the study, oversaw data analysis, and performed some of the writing	designed the study, oversaw data analysis, and performed some of the writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Supervision	YES
5563503	28480486	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5563503	28480486	BC	2	contributed to the study design, and critically revised the manuscript	contributed to the study design, and critically revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5563503	28480486	FP	2	contributed to the study design, and critically revised the manuscript	contributed to the study design, and critically revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5563503	28480486	GM	2	designed the study, oversaw data analysis, and critically revised the manuscript	designed the study, oversaw data analysis, and critically revised the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Supervision|Writing - Review & Editing	YES
5563503	28480486	LS	2	collected clinical data, and critically revised the manuscript	collected clinical data, and critically revised the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5563503	28480486	MA	2	oversaw data analysis, and critically revised the manuscript	oversaw data analysis, and critically revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Supervision|Writing - Review & Editing	YES
5563503	28480486	MM	2	performed the statistical analysis and wrote the initial draft of the manuscript	performed the statistical analysis and wrote the initial draft of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5563503	28480486	The authors	2	have no other relevant affiliations or financial involvement with any organisation or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript	have no other relevant affiliations or financial involvement with any organisation or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript	-	-	NO
5563503	28480486	UA	2	designed the study, oversaw data analysis, and performed some of the writing	designed the study, oversaw data analysis, and performed some of the writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Supervision	YES
5563503	28480486	VDA	2	collected clinical data, and critically revised the manuscript	collected clinical data, and critically revised the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5563503	28480486	VS	2	collected clinical data, and critically revised the manuscript	collected clinical data, and critically revised the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5597158	28970445	Aliki Peletidi	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5597158	28970445	Jennifer Bonnah	PLoS52	conceived and designed the questionnaires and interview schedule|performed the data collection	conceived and designed the questionnaires and interview schedule	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5597158	28970445	Jennifer Bonnah	PLoS52	conceived and designed the questionnaires and interview schedule|performed the data collection	performed the data collection	Performed the experiments	Investigation	YES
5597158	28970445	Muhammad Ismail	PLoS52	conceived and designed the questionnaires and interview schedule|performed the data collection	conceived and designed the questionnaires and interview schedule	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5597158	28970445	Muhammad Ismail	PLoS52	conceived and designed the questionnaires and interview schedule|performed the data collection	performed the data collection	Performed the experiments	Investigation	YES
5597158	28970445	Pedro Bandeira	PLoS52	conceived and designed the questionnaires and interview schedule|performed the data collection	conceived and designed the questionnaires and interview schedule	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5597158	28970445	Pedro Bandeira	PLoS52	conceived and designed the questionnaires and interview schedule|performed the data collection	performed the data collection	Performed the experiments	Investigation	YES
5597158	28970445	Reem Kayyali	PLoS52	conceived and designed the questionnaires and interview schedule|wrote the paper	conceived and designed the questionnaires and interview schedule	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5597158	28970445	Reem Kayyali	PLoS52	conceived and designed the questionnaires and interview schedule|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5597158	28970445	Zahra Hashim	PLoS52	conceived and designed the questionnaires and interview schedule|performed the data collection	conceived and designed the questionnaires and interview schedule	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5597158	28970445	Zahra Hashim	PLoS52	conceived and designed the questionnaires and interview schedule|performed the data collection	performed the data collection	Performed the experiments	Investigation	YES
5597158	28970445	all authors	PLoS52	played a part in data analysis	played a part in data analysis	Analyzed the data	Formal analysis	YES
3549343	23346015	D. Junker	2	are equally contributing authors	are equally contributing authors	-	-	NO
3549343	23346015	G. Schafer	2	are equally contributing authors	are equally contributing authors	-	-	NO
3549343	23346015	M.D.	2	are equally contributing authors|are equally contributing authors	are equally contributing authors	-	-	NO
3549343	23346015	M.D.	2	are equally contributing authors|are equally contributing authors	are equally contributing authors	-	-	NO
6021262	29884457	ADH	2	managed patients and collected clinical data	managed patients and collected clinical data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
6021262	29884457	AH	2	developed methodology|performed experiments|analyzed and interpreted data	developed methodology	Performed the experiments	Methodology	YES
6021262	29884457	AH	2	developed methodology|performed experiments|analyzed and interpreted data	performed experiments	Performed the experiments	Investigation	YES
6021262	29884457	AH	2	developed methodology|performed experiments|analyzed and interpreted data	analyzed and interpreted data	Analyzed the data	Formal analysis	YES
6021262	29884457	CG	2	analyzed and interpreted data	analyzed and interpreted data	Analyzed the data	Formal analysis	YES
6021262	29884457	GG	2	designed the study and wrote the manuscript|developed methodology|managed patients and collected clinical data|analyzed and interpreted data	designed the study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
6021262	29884457	GG	2	designed the study and wrote the manuscript|developed methodology|managed patients and collected clinical data|analyzed and interpreted data	developed methodology	Performed the experiments	Methodology	YES
6021262	29884457	GG	2	designed the study and wrote the manuscript|developed methodology|managed patients and collected clinical data|analyzed and interpreted data	managed patients and collected clinical data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
6021262	29884457	GG	2	designed the study and wrote the manuscript|developed methodology|managed patients and collected clinical data|analyzed and interpreted data	analyzed and interpreted data	Analyzed the data	Formal analysis	YES
6021262	29884457	GL	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
6021262	29884457	JK	2	developed methodology|analyzed and interpreted data	developed methodology	Performed the experiments	Methodology	YES
6021262	29884457	JK	2	developed methodology|analyzed and interpreted data	analyzed and interpreted data	Analyzed the data	Formal analysis	YES
6021262	29884457	KD	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
6021262	29884457	LS	2	designed the study and wrote the manuscript|developed methodology|managed patients and collected clinical data|analyzed and interpreted data	designed the study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
6021262	29884457	LS	2	designed the study and wrote the manuscript|developed methodology|managed patients and collected clinical data|analyzed and interpreted data	developed methodology	Performed the experiments	Methodology	YES
6021262	29884457	LS	2	designed the study and wrote the manuscript|developed methodology|managed patients and collected clinical data|analyzed and interpreted data	managed patients and collected clinical data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
6021262	29884457	LS	2	designed the study and wrote the manuscript|developed methodology|managed patients and collected clinical data|analyzed and interpreted data	analyzed and interpreted data	Analyzed the data	Formal analysis	YES
6021262	29884457	MHG	2	analyzed and interpreted data	analyzed and interpreted data	Analyzed the data	Formal analysis	YES
6021262	29884457	MS	2	managed patients and collected clinical data	managed patients and collected clinical data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
6021262	29884457	PD	2	supervised the study|developed methodology|managed patients and collected clinical data|analyzed and interpreted data	supervised the study	-	Supervision	YES
6021262	29884457	PD	2	supervised the study|developed methodology|managed patients and collected clinical data|analyzed and interpreted data	developed methodology	Performed the experiments	Methodology	YES
6021262	29884457	PD	2	supervised the study|developed methodology|managed patients and collected clinical data|analyzed and interpreted data	managed patients and collected clinical data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
6021262	29884457	PD	2	supervised the study|developed methodology|managed patients and collected clinical data|analyzed and interpreted data	analyzed and interpreted data	Analyzed the data	Formal analysis	YES
6021262	29884457	PS	2	managed patients and collected clinical data	managed patients and collected clinical data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
6021262	29884457	SG	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
6021262	29884457	TR	2	managed patients and collected clinical data	managed patients and collected clinical data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
6021262	29884457	WR	2	managed patients and collected clinical data	managed patients and collected clinical data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
6021262	29884457	all authors	2	critically reviewed the manuscript	critically reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
4405202	25897666	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405202	25897666	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405202	25897666	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405202	25897666	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405202	25897666	QH	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405202	25897666	WG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405202	25897666	WS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4405202	25897666	WS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405202	25897666	YD	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405202	25897666	ZZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4995478	27594993	Akshay Malhotra	7	wrote paper	wrote paper	Wrote the paper	Writing - Original Draft	YES
4995478	27594993	Gillian Cribb	7	consultant involved in case and reviewed paper	consultant involved in case and reviewed paper	Wrote the paper	Writing - Review & Editing	YES
4995478	27594993	Paul Cool	7	consultant involved in case and reviewed paper	consultant involved in case and reviewed paper	Wrote the paper	Writing - Review & Editing	YES
4995478	27594993	Rohit Singh	7	wrote paper	wrote paper	Wrote the paper	Writing - Original Draft	YES
4995478	27594993	Stuart Hay	7	consultant involved in case and reviewed paper	consultant involved in case and reviewed paper	Wrote the paper	Writing - Review & Editing	YES
5249042	28105938	AK	2	wrote the manuscript text|carried out the bioinformatic analysis|supervised the bioinformatic research and text of the manuscript	wrote the manuscript text	Wrote the paper	Writing - Original Draft	YES
5249042	28105938	AK	2	wrote the manuscript text|carried out the bioinformatic analysis|supervised the bioinformatic research and text of the manuscript	carried out the bioinformatic analysis	Performed the experiments	Formal analysis|Investigation	YES
5249042	28105938	AK	2	wrote the manuscript text|carried out the bioinformatic analysis|supervised the bioinformatic research and text of the manuscript	supervised the bioinformatic research and text of the manuscript	Wrote the paper	Formal analysis|Supervision|Writing - Original Draft	YES
5249042	28105938	AM	2	wrote the manuscript text|carried out the bioinformatic analysis|supervised the bioinformatic research and text of the manuscript	wrote the manuscript text	Wrote the paper	Writing - Original Draft	YES
5249042	28105938	AM	2	wrote the manuscript text|carried out the bioinformatic analysis|supervised the bioinformatic research and text of the manuscript	carried out the bioinformatic analysis	Performed the experiments	Formal analysis|Investigation	YES
5249042	28105938	AM	2	wrote the manuscript text|carried out the bioinformatic analysis|supervised the bioinformatic research and text of the manuscript	supervised the bioinformatic research and text of the manuscript	Wrote the paper	Formal analysis|Supervision|Writing - Original Draft	YES
5249042	28105938	AS	2	carried out the experiments|carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5249042	28105938	AS	2	carried out the experiments|carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5249042	28105938	EP	2	wrote the manuscript text|carried out the experiments	wrote the manuscript text	Wrote the paper	Writing - Original Draft	YES
5249042	28105938	EP	2	wrote the manuscript text|carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5249042	28105938	GK	2	wrote the manuscript text|carried out the bioinformatic analysis	wrote the manuscript text	Wrote the paper	Writing - Original Draft	YES
5249042	28105938	GK	2	wrote the manuscript text|carried out the bioinformatic analysis	carried out the bioinformatic analysis	Performed the experiments	Formal analysis|Investigation	YES
5249042	28105938	MS	2	wrote the manuscript text|carried out the experiments	wrote the manuscript text	Wrote the paper	Writing - Original Draft	YES
5249042	28105938	MS	2	wrote the manuscript text|carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5249042	28105938	SZ	2	carried out the experiments|carried out the bioinformatic analysis	carried out the experiments	Performed the experiments	Investigation	YES
5249042	28105938	SZ	2	carried out the experiments|carried out the bioinformatic analysis	carried out the bioinformatic analysis	Performed the experiments	Formal analysis|Investigation	YES
5249042	28105938	ZG	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5578943	28861763	All	2	author gave their consent to publish this manuscript|participants signed informed consent before any study-related procedures were performed	author gave their consent to publish this manuscript	-	-	NO
5578943	28861763	All	2	author gave their consent to publish this manuscript|participants signed informed consent before any study-related procedures were performed	participants signed informed consent before any study-related procedures were performed	Performed the experiments	Investigation	YES
5578943	28861763	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5578943	28861763	All other authors	2	have no interests to declare	have no interests to declare	-	-	NO
5578943	28861763	BC	2	participated in data interpretation and manuscript preparation	participated in data interpretation and manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5578943	28861763	BM	2	participated in the implementation of machine learning algorithms, data interpretation, and manuscript preparation	participated in the implementation of machine learning algorithms, data interpretation, and manuscript preparation	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Software|Writing - Original Draft	YES
5578943	28861763	GZ	2	participated in data acquisition, data interpretation, and manuscript preparation	participated in data acquisition, data interpretation, and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5578943	28861763	IB	2	participated in data preprocessing, data interpretation, and manuscript preparation	participated in data preprocessing, data interpretation, and manuscript preparation	Analyzed the data|Wrote the paper	Data curation|Formal analysis|Writing - Original Draft	YES
5578943	28861763	IP	2	participated in data preprocessing, data interpretation, and manuscript preparation	participated in data preprocessing, data interpretation, and manuscript preparation	Analyzed the data|Wrote the paper	Data curation|Formal analysis|Writing - Original Draft	YES
5578943	28861763	IRB	2	supervised the ouston and can only be accessed by authorized personnel under the	supervised the ouston and can only be accessed by authorized personnel under the	-	Supervision	YES
5578943	28861763	JS	2	participated in data acquisition, data interpretation, and manuscript preparation	participated in data acquisition, data interpretation, and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5578943	28861763	MW	2	was in charge of data preprocessing, implementation of machine learning algorithms, data interpretation, and manuscript preparation	was in charge of data preprocessing, implementation of machine learning algorithms, data interpretation, and manuscript preparation	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Data curation|Formal analysis|Investigation|Software|Writing - Original Draft	YES
5578943	28861763	TF	2	participated in data acquisition, data interpretation, and manuscript preparation	participated in data acquisition, data interpretation, and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4670842	26639110	All authors	2	contributed to literature review and writing the manuscript	contributed to literature review and writing the manuscript	Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5524819	28791038	AG	5	conceived and wrote the article with significant intellectual input from all authors: JC	conceived and wrote the article with significant intellectual input from all authors: JC	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5594427	28893284	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5594427	28893284	CK	2	wrote and edited the manuscript	wrote and edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5594427	28893284	DV	2	wrote and edited the manuscript	wrote and edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5594427	28893284	JMW	2	wrote and edited the manuscript	wrote and edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5594427	28893284	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
4477061	26180778	Rui Li	2	contributed equally to this work	contributed equally to this work	-	-	NO
4477061	26180778	Weicong Ren	2	contributed equally to this work	contributed equally to this work	-	-	NO
4405203	25897790	DCJ	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405203	25897790	DCJ	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4405203	25897790	HHK	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405203	25897790	JTK	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405203	25897790	JY	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405203	25897790	KH	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4405203	25897790	KH	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405203	25897790	YHC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405203	25897790	YHC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405203	25897790	YHC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405203	25897790	YP	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5597171	28975905	J. Yang	2	were all involved in the planning and development of the project, collection, analysis of data and writing of the manuscript	were all involved in the planning and development of the project, collection, analysis of data and writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5597171	28975905	Mitesh Doshi	2	were all involved in the planning and development of the project, collection, analysis of data and writing of the manuscript	were all involved in the planning and development of the project, collection, analysis of data and writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5597171	28975905	Nancy A. Mason	2	were all involved in the planning and development of the project, collection, analysis of data and writing of the manuscript	were all involved in the planning and development of the project, collection, analysis of data and writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4995479	27594994	Enver Reyhan	7	Study design, practise	Study design, practise	Conceived and designed the experiments	Methodology	YES
4995479	27594994	Hilmi Bozkurt	7	Data collections, data analysis and writing	Data collections, data analysis and writing	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation	YES
4995479	27594994	Mehmet Aziret	7	Practise, writing	Practise, writing	Wrote the paper	-	YES
4995479	27594994	Mehmet Kemal Okuyan	7	Practical, design	Practical, design	Conceived and designed the experiments	-	YES
4995479	27594994	Oktay Irkorucu	7	Study design, interpretation	Study design, interpretation	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
6021272	29903570	A. Santeford	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
6021272	29903570	A. Sene	CRediT	Conceptualization|Investigation|Writing - original draft|Writing - review & editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6021272	29903570	A. Sene	CRediT	Conceptualization|Investigation|Writing - original draft|Writing - review & editing	Investigation	Performed the experiments	Investigation	YES
6021272	29903570	A. Sene	CRediT	Conceptualization|Investigation|Writing - original draft|Writing - review & editing	Writing - original draft	Wrote the paper	Writing - Original Draft	YES
6021272	29903570	A. Sene	CRediT	Conceptualization|Investigation|Writing - original draft|Writing - review & editing	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
6021272	29903570	D.S.O.	CRediT	Writing - review & editing|Supervision|Funding acquisition	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
6021272	29903570	D.S.O.	CRediT	Writing - review & editing|Supervision|Funding acquisition	Supervision	-	Supervision	YES
6021272	29903570	D.S.O.	CRediT	Writing - review & editing|Supervision|Funding acquisition	Funding acquisition	-	Funding acquisition	YES
6021272	29903570	H.F.	CRediT	Investigation|Writing - review & editing	Investigation	Performed the experiments	Investigation	YES
6021272	29903570	H.F.	CRediT	Investigation|Writing - review & editing	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
6021272	29903570	I.U.M.	CRediT	Supervision|Funding acquisition	Supervision	-	Supervision	YES
6021272	29903570	I.U.M.	CRediT	Supervision|Funding acquisition	Funding acquisition	-	Funding acquisition	YES
6021272	29903570	J.B.L.	CRediT	Conceptualization|Investigation|Writing - original draft|Writing - review & editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6021272	29903570	J.B.L.	CRediT	Conceptualization|Investigation|Writing - original draft|Writing - review & editing	Investigation	Performed the experiments	Investigation	YES
6021272	29903570	J.B.L.	CRediT	Conceptualization|Investigation|Writing - original draft|Writing - review & editing	Writing - original draft	Wrote the paper	Writing - Original Draft	YES
6021272	29903570	J.B.L.	CRediT	Conceptualization|Investigation|Writing - original draft|Writing - review & editing	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
6021272	29903570	M.M.L.	CRediT	Investigation|Writing - review & editing	Investigation	Performed the experiments	Investigation	YES
6021272	29903570	M.M.L.	CRediT	Investigation|Writing - review & editing	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
6021272	29903570	N.B.	CRediT	Investigation|Writing - review & editing	Investigation	Performed the experiments	Investigation	YES
6021272	29903570	N.B.	CRediT	Investigation|Writing - review & editing	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
6021272	29903570	R.S.	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
6021272	29903570	R.S.A.	CRediT	Conceptualization|Writing - review & editing|Supervision|Funding acquisition	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6021272	29903570	R.S.A.	CRediT	Conceptualization|Writing - review & editing|Supervision|Funding acquisition	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
6021272	29903570	R.S.A.	CRediT	Conceptualization|Writing - review & editing|Supervision|Funding acquisition	Supervision	-	Supervision	YES
6021272	29903570	R.S.A.	CRediT	Conceptualization|Writing - review & editing|Supervision|Funding acquisition	Funding acquisition	-	Funding acquisition	YES
6021272	29903570	V.A.S.	CRediT	Investigation|Writing - review & editing	Investigation	Performed the experiments	Investigation	YES
6021272	29903570	V.A.S.	CRediT	Investigation|Writing - review & editing	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
5249044	28105939	ASA	2	participated in statistical and phylogenetic analyses	participated in statistical and phylogenetic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5249044	28105939	AVG	2	participated in statistical and phylogenetic analyses	participated in statistical and phylogenetic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5249044	28105939	DYS	2	are responsible for conception and design of the study|carried out taxonomic sampling|participated in statistical and phylogenetic analyses	are responsible for conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5249044	28105939	DYS	2	are responsible for conception and design of the study|carried out taxonomic sampling|participated in statistical and phylogenetic analyses	carried out taxonomic sampling	Performed the experiments	Investigation	YES
5249044	28105939	DYS	2	are responsible for conception and design of the study|carried out taxonomic sampling|participated in statistical and phylogenetic analyses	participated in statistical and phylogenetic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5249044	28105939	EAS	2	carried out taxonomic sampling|participated in statistical and phylogenetic analyses	carried out taxonomic sampling	Performed the experiments	Investigation	YES
5249044	28105939	EAS	2	carried out taxonomic sampling|participated in statistical and phylogenetic analyses	participated in statistical and phylogenetic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5249044	28105939	EVR	2	are responsible for conception and design of the study|carried out taxonomic sampling|performed the laboratory works|are responsible for assembly and annotation of mitochondrial genomes|wrote the manuscript	are responsible for conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5249044	28105939	EVR	2	are responsible for conception and design of the study|carried out taxonomic sampling|performed the laboratory works|are responsible for assembly and annotation of mitochondrial genomes|wrote the manuscript	carried out taxonomic sampling	Performed the experiments	Investigation	YES
5249044	28105939	EVR	2	are responsible for conception and design of the study|carried out taxonomic sampling|performed the laboratory works|are responsible for assembly and annotation of mitochondrial genomes|wrote the manuscript	performed the laboratory works	Performed the experiments	Investigation	YES
5249044	28105939	EVR	2	are responsible for conception and design of the study|carried out taxonomic sampling|performed the laboratory works|are responsible for assembly and annotation of mitochondrial genomes|wrote the manuscript	are responsible for assembly and annotation of mitochondrial genomes	Analyzed the data	Data curation|Formal analysis	YES
5249044	28105939	EVR	2	are responsible for conception and design of the study|carried out taxonomic sampling|performed the laboratory works|are responsible for assembly and annotation of mitochondrial genomes|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5249044	28105939	KVM	2	are responsible for assembly and annotation of mitochondrial genomes	are responsible for assembly and annotation of mitochondrial genomes	Analyzed the data	Data curation|Formal analysis	YES
5249044	28105939	RMK	2	performed the morphological identification of species|participated in statistical and phylogenetic analyses	performed the morphological identification of species	Performed the experiments	Investigation	YES
5249044	28105939	RMK	2	performed the morphological identification of species|participated in statistical and phylogenetic analyses	participated in statistical and phylogenetic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5249044	28105939	VVA	2	participated in statistical and phylogenetic analyses	participated in statistical and phylogenetic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5524824	28791042	EO	2	designed research, analyzed data, wrote manuscript, assembled and edited figures	designed research, analyzed data, wrote manuscript, assembled and edited figures	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Visualization|Writing - Original Draft|Writing - Review & Editing	YES
5524824	28791042	GH	2	designed research, analyzed data, wrote manuscript, assembled and edited figures	designed research, analyzed data, wrote manuscript, assembled and edited figures	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Visualization|Writing - Original Draft|Writing - Review & Editing	YES
5524824	28791042	J-YZ	2	designed research, analyzed data, wrote manuscript, assembled and edited figures	designed research, analyzed data, wrote manuscript, assembled and edited figures	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Visualization|Writing - Original Draft|Writing - Review & Editing	YES
5524824	28791042	JK	2	conducted research and analyzed data	conducted research and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5524824	28791042	SK	2	designed experiments, conducted research, analyzed data	designed experiments, conducted research, analyzed data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5524824	28791042	TN	2	conducted experiments	conducted experiments	Performed the experiments	Investigation	YES
5524824	28791042	YL	2	designed research, analyzed data, wrote manuscript, assembled and edited figures	designed research, analyzed data, wrote manuscript, assembled and edited figures	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Visualization|Writing - Original Draft|Writing - Review & Editing	YES
5594430	28893304	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5594430	28893304	JL	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5594430	28893304	KF	2	offered writing support and is the principal investigator	offered writing support and is the principal investigator	Conceived and designed the experiments|Wrote the paper	Conceptualization|Funding acquisition	YES
5594430	28893304	The Immune Quiescence	2	study was approved by both the university of nairobi and university of manitoba ethic board	study was approved by both the university of nairobi and university of manitoba ethic board	-	-	NO
5594430	28893304	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
4405204	25898257	HS	PLoS5	Contributed reagents/materials/analysis tools|Designed the software used in analysis	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405204	25898257	HS	PLoS5	Contributed reagents/materials/analysis tools|Designed the software used in analysis	Designed the software used in analysis	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
4405204	25898257	LW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405204	25898257	TZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405204	25898257	WW	PLoS5	Analyzed the data|Designed the software used in analysis	Analyzed the data	Analyzed the data	Formal analysis	YES
4405204	25898257	WW	PLoS5	Analyzed the data|Designed the software used in analysis	Designed the software used in analysis	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
4405204	25898257	XH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405204	25898257	XQ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405204	25898257	XY	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405204	25898257	XY	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405204	25898257	YD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405204	25898257	YD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405204	25898257	YD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405204	25898257	YD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405204	25898257	YY	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405204	25898257	YY	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405204	25898257	YY	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405204	25898257	YY	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5011080	27625783	Dr Chaudhry	2	was involved in immunohistochemistry data collection, tissue sample data processing, and assisted in manuscript preparation	was involved in immunohistochemistry data collection, tissue sample data processing, and assisted in manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Investigation|Writing - Original Draft	YES
5011080	27625783	Dr Makaram	2	was involved in the data collection, interpretation, and manuscript preparation	was involved in the data collection, interpretation, and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5011080	27625783	Mr Srinivasan	2	oversaw the creation of the report and was additionally involved in the care of the patient	oversaw the creation of the report and was additionally involved in the care of the patient	Performed the experiments	Investigation|Supervision	YES
6085496	29936136	Akira Ishii	1	Data analysis	Data analysis	Analyzed the data	Formal analysis	YES
6085496	29936136	Hiroki Fukuda	1	Data analysis|Tables	Data analysis	Analyzed the data	Formal analysis	YES
6085496	29936136	Hiroki Fukuda	1	Data analysis|Tables	Tables	-	-	NO
6085496	29936136	Kazuhiro Shindo	1	Tables	Tables	-	-	NO
6085496	29936136	Masafumi Kitakaze	1	Study concept and design|Writing	Study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6085496	29936136	Masafumi Kitakaze	1	Study concept and design|Writing	Writing	Wrote the paper	-	YES
6085496	29936136	Shin Ito	1	Data analysis	Data analysis	Analyzed the data	Formal analysis	YES
6085496	29936136	Takashi Washio	1	Study concept and design	Study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5587525	28879470	AF	2	worked on the conception and design of the study and critically revising the manuscript in preparation for submission	worked on the conception and design of the study and critically revising the manuscript in preparation for submission	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5587525	28879470	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5587525	28879470	BM	2	worked on the conception and design of the study and critically revising the manuscript in preparation for submission	worked on the conception and design of the study and critically revising the manuscript in preparation for submission	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5587525	28879470	GMH	2	conducted the analyses for the manuscript, interpreted the results and drafted the manuscript	conducted the analyses for the manuscript, interpreted the results and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5587525	28879470	HF	2	were involved in the data analysis, interpretation of the findings and drafting the manuscript	were involved in the data analysis, interpretation of the findings and drafting the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5587525	28879470	PM	2	worked on the conception and design of the study and critically revising the manuscript in preparation for submission	worked on the conception and design of the study and critically revising the manuscript in preparation for submission	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5587525	28879470	SC-W	2	were involved in the data analysis, interpretation of the findings and drafting the manuscript	were involved in the data analysis, interpretation of the findings and drafting the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5587525	28879470	UR	2	were involved in the data analysis, interpretation of the findings and drafting the manuscript	were involved in the data analysis, interpretation of the findings and drafting the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4670843	26639113	RH	2	designed, reviewed and revised the manuscript	designed, reviewed and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Review & Editing	YES
4670843	26639113	SL	2	designed and wrote the manuscript	designed and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
5597173	28975907	All authors	2	actively participated in the delphi review by the small expert committee	actively participated in the delphi review by the small expert committee	-	-	NO
5597173	28975907	Brian Gennery	2	wrote the initial competence framework and gave advice on subsequent versions	wrote the initial competence framework and gave advice on subsequent versions	Wrote the paper	Writing - Original Draft	YES
5597173	28975907	EAFP	2	critically reviewed early versions of the paper	critically reviewed early versions of the paper	Wrote the paper	Writing - Review & Editing	YES
5597173	28975907	Giuseppe Ronsisvalle	2	gave advice based on their knowledge of biotechnology teaching	gave advice based on their knowledge of biotechnology teaching	-	-	NO
5597173	28975907	Gunther Pauwels	2	gave advice based on their knowledge of biotechnology practice	gave advice based on their knowledge of biotechnology practice	-	-	NO
5597173	28975907	Jeffrey Atkinson	2	directed the project|ran the survey, analysed the results and wrote the paper	directed the project	-	Supervision	YES
5597173	28975907	Jeffrey Atkinson	2	directed the project|ran the survey, analysed the results and wrote the paper	ran the survey, analysed the results and wrote the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5597173	28975907	Keith Wilson	2	gave advice based on their knowledge of biotechnology teaching	gave advice based on their knowledge of biotechnology teaching	-	-	NO
5597173	28975907	Kristien De Paepe	2	directed the project	directed the project	-	Supervision	YES
5597173	28975907	Pat Crowley	2	wrote the initial competence framework and gave advice on subsequent versions	wrote the initial competence framework and gave advice on subsequent versions	Wrote the paper	Writing - Original Draft	YES
5597173	28975907	Vitor Sousa	2	gave advice based on their knowledge of biotechnology practice	gave advice based on their knowledge of biotechnology practice	-	-	NO
5011162	27625785	Giuseppe Tisone	PLoS52	edit and revised the paper and all authors approved the final version of the manuscript	edit and revised the paper and all authors approved the final version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5011162	27625785	Laura Fazzolari	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5011162	27625785	Leonardo Baiocchi	PLoS52	edit and revised the paper and all authors approved the final version of the manuscript	edit and revised the paper and all authors approved the final version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5011162	27625785	Marco Pellicciaro	PLoS52	take and edit the photos	take and edit the photos	-	-	NO
5011162	27625785	Matteo Manuelli	PLoS52	take and edit the photos	take and edit the photos	-	-	NO
5011162	27625785	Tommaso Maria Manzia	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5524829	28791039	AJ	2	provided technical help throughout the research and checked the manuscript critically for grammatical errors	provided technical help throughout the research and checked the manuscript critically for grammatical errors	Wrote the paper	Writing - Review & Editing	YES
5524829	28791039	IM	2	provided technical help throughout the research and checked the manuscript critically for grammatical errors	provided technical help throughout the research and checked the manuscript critically for grammatical errors	Wrote the paper	Writing - Review & Editing	YES
5524829	28791039	MK	2	equally contributed to this manuscript	equally contributed to this manuscript	-	-	NO
5524829	28791039	SS	2	equally contributed to this manuscript	equally contributed to this manuscript	-	-	NO
5251313	28107812	All authors	2	contributed to study conception and design|reviewed and approved the final version of the manuscript	contributed to study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5251313	28107812	All authors	2	contributed to study conception and design|reviewed and approved the final version of the manuscript	reviewed and approved the final version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5251313	28107812	CJF	2	aided with experimental design and supervised the whole project|provided spinal cord and brainstem data	aided with experimental design and supervised the whole project	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Supervision	YES
5251313	28107812	CJF	2	aided with experimental design and supervised the whole project|provided spinal cord and brainstem data	provided spinal cord and brainstem data	Contributed reagents/materials/analysis tools	Resources	YES
5251313	28107812	CTB	2	aided with experimental design and supervised the whole project	aided with experimental design and supervised the whole project	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Supervision	YES
5251313	28107812	EYS	2	wrote the manuscript and made the figures|provided the cerebellar rna seq data	wrote the manuscript and made the figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5251313	28107812	EYS	2	wrote the manuscript and made the figures|provided the cerebellar rna seq data	provided the cerebellar rna seq data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5251313	28107812	JDM	2	aided with experimental design and supervised the whole project|provided the cerebellar rna seq data	aided with experimental design and supervised the whole project	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Supervision	YES
5251313	28107812	JDM	2	aided with experimental design and supervised the whole project|provided the cerebellar rna seq data	provided the cerebellar rna seq data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5251313	28107812	MCP	2	provided the cerebellar rna seq data	provided the cerebellar rna seq data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5251313	28107812	MJM	2	provided retina and skin data	provided retina and skin data	Contributed reagents/materials/analysis tools	Resources	YES
5251313	28107812	PJR	2	provided both embryonic tissue data	provided both embryonic tissue data	Contributed reagents/materials/analysis tools	Resources	YES
5251313	28107812	RRB	2	provided retina and skin data	provided retina and skin data	Contributed reagents/materials/analysis tools	Resources	YES
5251313	28107812	SJV	2	provided muscle data	provided muscle data	Contributed reagents/materials/analysis tools	Resources	YES
5251313	28107812	TAM	2	produced the annotation pipeline and did the data analysis with oversight on writing of the manuscript as well as figure formation	produced the annotation pipeline and did the data analysis with oversight on writing of the manuscript as well as figure formation	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Formal analysis|Investigation|Supervision|Visualization|Writing - Original Draft	YES
4671285	26642452	Each author	2	contributed to the writing of this manuscript	contributed to the writing of this manuscript	Wrote the paper	Writing - Original Draft	YES
5594457	28893280	All authors	2	contributed to writing and reviewing the manuscript|read and approved the final manuscript	contributed to writing and reviewing the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5594457	28893280	All authors	2	contributed to writing and reviewing the manuscript|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5018090	27642515	A Chang	7	assisted in writing of paper	assisted in writing of paper	Wrote the paper	Writing - Original Draft	YES
5018090	27642515	M Borg	7	assisted in writing of paper	assisted in writing of paper	Wrote the paper	Writing - Original Draft	YES
5018090	27642515	R Som	7	conceived paper, assisted in literature search and writing of paper. C	conceived paper, assisted in literature search and writing of paper. C	Conceived and designed the experiments|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
5018090	27642515	S Ramar	7	assisted in writing of paper	assisted in writing of paper	Wrote the paper	Writing - Original Draft	YES
5018090	27642515	S Sait	7	conducted literature search and wrote paper	conducted literature search and wrote paper	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4405205	25897968	JY	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405205	25897968	JY	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405205	25897968	JY	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405205	25897968	PL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4405205	25897968	PL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405205	25897968	RC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405205	25897968	RC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405205	25897968	RC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405205	25897968	RC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405205	25897968	ZW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
6085507	29941341	All authors	2	contributed to the drafting of the paper	contributed to the drafting of the paper	Wrote the paper	Writing - Original Draft	YES
6085507	29941341	EW	2	obtained funding for the trial	obtained funding for the trial	-	Funding acquisition	YES
6085507	29941341	J.M.	2	helped design the trial, providing statistical input in both the design and in the final analysis	helped design the trial, providing statistical input in both the design and in the final analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
6085507	29941341	SB	2	provided input in the design and drafting of the paper	provided input in the design and drafting of the paper	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
6085507	29941341	ST	2	helped analyse the data and drafted the initial versions of the paper	helped analyse the data and drafted the initial versions of the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6085507	29941341	TGJ	2	provided input in the analysis and drafting of the paper	provided input in the analysis and drafting of the paper	Wrote the paper	Writing - Original Draft	YES
5610955	28944443	GR	1	Following authors make substantial contributions to conception and design, and/or acquisition of data, and/or analysis and interpretation of data|Following authors participate in drafting the article or revising it critically for important intellectual content|Following authors give final approval of the version to be submitted and any revised version	Following authors make substantial contributions to conception and design, and/or acquisition of data, and/or analysis and interpretation of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
5610955	28944443	GR	1	Following authors make substantial contributions to conception and design, and/or acquisition of data, and/or analysis and interpretation of data|Following authors participate in drafting the article or revising it critically for important intellectual content|Following authors give final approval of the version to be submitted and any revised version	Following authors participate in drafting the article or revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5610955	28944443	GR	1	Following authors make substantial contributions to conception and design, and/or acquisition of data, and/or analysis and interpretation of data|Following authors participate in drafting the article or revising it critically for important intellectual content|Following authors give final approval of the version to be submitted and any revised version	Following authors give final approval of the version to be submitted and any revised version	Wrote the paper	Writing - Review & Editing	YES
5610955	28944443	GSL	1	Following authors make substantial contributions to conception and design, and/or acquisition of data, and/or analysis and interpretation of data|Following authors participate in drafting the article or revising it critically for important intellectual content|Following authors give final approval of the version to be submitted and any revised version	Following authors make substantial contributions to conception and design, and/or acquisition of data, and/or analysis and interpretation of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
5610955	28944443	GSL	1	Following authors make substantial contributions to conception and design, and/or acquisition of data, and/or analysis and interpretation of data|Following authors participate in drafting the article or revising it critically for important intellectual content|Following authors give final approval of the version to be submitted and any revised version	Following authors participate in drafting the article or revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5610955	28944443	GSL	1	Following authors make substantial contributions to conception and design, and/or acquisition of data, and/or analysis and interpretation of data|Following authors participate in drafting the article or revising it critically for important intellectual content|Following authors give final approval of the version to be submitted and any revised version	Following authors give final approval of the version to be submitted and any revised version	Wrote the paper	Writing - Review & Editing	YES
5610955	28944443	HG	1	Following authors make substantial contributions to conception and design, and/or acquisition of data, and/or analysis and interpretation of data|Following authors participate in drafting the article or revising it critically for important intellectual content|Following authors give final approval of the version to be submitted and any revised version	Following authors make substantial contributions to conception and design, and/or acquisition of data, and/or analysis and interpretation of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
5610955	28944443	HG	1	Following authors make substantial contributions to conception and design, and/or acquisition of data, and/or analysis and interpretation of data|Following authors participate in drafting the article or revising it critically for important intellectual content|Following authors give final approval of the version to be submitted and any revised version	Following authors participate in drafting the article or revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5610955	28944443	HG	1	Following authors make substantial contributions to conception and design, and/or acquisition of data, and/or analysis and interpretation of data|Following authors participate in drafting the article or revising it critically for important intellectual content|Following authors give final approval of the version to be submitted and any revised version	Following authors give final approval of the version to be submitted and any revised version	Wrote the paper	Writing - Review & Editing	YES
5610955	28944443	LA	1	Following authors make substantial contributions to conception and design, and/or acquisition of data, and/or analysis and interpretation of data	Following authors make substantial contributions to conception and design, and/or acquisition of data, and/or analysis and interpretation of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
5610955	28944443	MAF	1	Following authors make substantial contributions to conception and design, and/or acquisition of data, and/or analysis and interpretation of data|Following authors participate in drafting the article or revising it critically for important intellectual content|Following authors give final approval of the version to be submitted and any revised version	Following authors make substantial contributions to conception and design, and/or acquisition of data, and/or analysis and interpretation of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
5610955	28944443	MAF	1	Following authors make substantial contributions to conception and design, and/or acquisition of data, and/or analysis and interpretation of data|Following authors participate in drafting the article or revising it critically for important intellectual content|Following authors give final approval of the version to be submitted and any revised version	Following authors participate in drafting the article or revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5610955	28944443	MAF	1	Following authors make substantial contributions to conception and design, and/or acquisition of data, and/or analysis and interpretation of data|Following authors participate in drafting the article or revising it critically for important intellectual content|Following authors give final approval of the version to be submitted and any revised version	Following authors give final approval of the version to be submitted and any revised version	Wrote the paper	Writing - Review & Editing	YES
5610955	28944443	NW	1	Following authors make substantial contributions to conception and design, and/or acquisition of data, and/or analysis and interpretation of data|Following authors participate in drafting the article or revising it critically for important intellectual content|Following authors give final approval of the version to be submitted and any revised version	Following authors make substantial contributions to conception and design, and/or acquisition of data, and/or analysis and interpretation of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
5610955	28944443	NW	1	Following authors make substantial contributions to conception and design, and/or acquisition of data, and/or analysis and interpretation of data|Following authors participate in drafting the article or revising it critically for important intellectual content|Following authors give final approval of the version to be submitted and any revised version	Following authors participate in drafting the article or revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5610955	28944443	NW	1	Following authors make substantial contributions to conception and design, and/or acquisition of data, and/or analysis and interpretation of data|Following authors participate in drafting the article or revising it critically for important intellectual content|Following authors give final approval of the version to be submitted and any revised version	Following authors give final approval of the version to be submitted and any revised version	Wrote the paper	Writing - Review & Editing	YES
5610955	28944443	PEK	1	Following authors make substantial contributions to conception and design, and/or acquisition of data, and/or analysis and interpretation of data|Following authors participate in drafting the article or revising it critically for important intellectual content|Following authors give final approval of the version to be submitted and any revised version	Following authors make substantial contributions to conception and design, and/or acquisition of data, and/or analysis and interpretation of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
5610955	28944443	PEK	1	Following authors make substantial contributions to conception and design, and/or acquisition of data, and/or analysis and interpretation of data|Following authors participate in drafting the article or revising it critically for important intellectual content|Following authors give final approval of the version to be submitted and any revised version	Following authors participate in drafting the article or revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5610955	28944443	PEK	1	Following authors make substantial contributions to conception and design, and/or acquisition of data, and/or analysis and interpretation of data|Following authors participate in drafting the article or revising it critically for important intellectual content|Following authors give final approval of the version to be submitted and any revised version	Following authors give final approval of the version to be submitted and any revised version	Wrote the paper	Writing - Review & Editing	YES
5610955	28944443	RMP	1	Following authors make substantial contributions to conception and design, and/or acquisition of data, and/or analysis and interpretation of data|Following authors participate in drafting the article or revising it critically for important intellectual content|Following authors give final approval of the version to be submitted and any revised version	Following authors make substantial contributions to conception and design, and/or acquisition of data, and/or analysis and interpretation of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
5610955	28944443	RMP	1	Following authors make substantial contributions to conception and design, and/or acquisition of data, and/or analysis and interpretation of data|Following authors participate in drafting the article or revising it critically for important intellectual content|Following authors give final approval of the version to be submitted and any revised version	Following authors participate in drafting the article or revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5610955	28944443	RMP	1	Following authors make substantial contributions to conception and design, and/or acquisition of data, and/or analysis and interpretation of data|Following authors participate in drafting the article or revising it critically for important intellectual content|Following authors give final approval of the version to be submitted and any revised version	Following authors give final approval of the version to be submitted and any revised version	Wrote the paper	Writing - Review & Editing	YES
5610955	28944443	RWK	1	Following authors make substantial contributions to conception and design, and/or acquisition of data, and/or analysis and interpretation of data|Following authors participate in drafting the article or revising it critically for important intellectual content|Following authors give final approval of the version to be submitted and any revised version	Following authors make substantial contributions to conception and design, and/or acquisition of data, and/or analysis and interpretation of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
5610955	28944443	RWK	1	Following authors make substantial contributions to conception and design, and/or acquisition of data, and/or analysis and interpretation of data|Following authors participate in drafting the article or revising it critically for important intellectual content|Following authors give final approval of the version to be submitted and any revised version	Following authors participate in drafting the article or revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5610955	28944443	RWK	1	Following authors make substantial contributions to conception and design, and/or acquisition of data, and/or analysis and interpretation of data|Following authors participate in drafting the article or revising it critically for important intellectual content|Following authors give final approval of the version to be submitted and any revised version	Following authors give final approval of the version to be submitted and any revised version	Wrote the paper	Writing - Review & Editing	YES
5610955	28944443	SM	1	Following authors make substantial contributions to conception and design, and/or acquisition of data, and/or analysis and interpretation of data|Following authors participate in drafting the article or revising it critically for important intellectual content|Following authors give final approval of the version to be submitted and any revised version	Following authors make substantial contributions to conception and design, and/or acquisition of data, and/or analysis and interpretation of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
5610955	28944443	SM	1	Following authors make substantial contributions to conception and design, and/or acquisition of data, and/or analysis and interpretation of data|Following authors participate in drafting the article or revising it critically for important intellectual content|Following authors give final approval of the version to be submitted and any revised version	Following authors participate in drafting the article or revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5610955	28944443	SM	1	Following authors make substantial contributions to conception and design, and/or acquisition of data, and/or analysis and interpretation of data|Following authors participate in drafting the article or revising it critically for important intellectual content|Following authors give final approval of the version to be submitted and any revised version	Following authors give final approval of the version to be submitted and any revised version	Wrote the paper	Writing - Review & Editing	YES
5610955	28944443	TS	1	Following authors make substantial contributions to conception and design, and/or acquisition of data, and/or analysis and interpretation of data|Following authors participate in drafting the article or revising it critically for important intellectual content|Following authors give final approval of the version to be submitted and any revised version	Following authors make substantial contributions to conception and design, and/or acquisition of data, and/or analysis and interpretation of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
5610955	28944443	TS	1	Following authors make substantial contributions to conception and design, and/or acquisition of data, and/or analysis and interpretation of data|Following authors participate in drafting the article or revising it critically for important intellectual content|Following authors give final approval of the version to be submitted and any revised version	Following authors participate in drafting the article or revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5610955	28944443	TS	1	Following authors make substantial contributions to conception and design, and/or acquisition of data, and/or analysis and interpretation of data|Following authors participate in drafting the article or revising it critically for important intellectual content|Following authors give final approval of the version to be submitted and any revised version	Following authors give final approval of the version to be submitted and any revised version	Wrote the paper	Writing - Review & Editing	YES
5610955	28944443	WAN	1	Following authors make substantial contributions to conception and design, and/or acquisition of data, and/or analysis and interpretation of data|Following authors participate in drafting the article or revising it critically for important intellectual content|Following authors give final approval of the version to be submitted and any revised version	Following authors make substantial contributions to conception and design, and/or acquisition of data, and/or analysis and interpretation of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
5610955	28944443	WAN	1	Following authors make substantial contributions to conception and design, and/or acquisition of data, and/or analysis and interpretation of data|Following authors participate in drafting the article or revising it critically for important intellectual content|Following authors give final approval of the version to be submitted and any revised version	Following authors participate in drafting the article or revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5610955	28944443	WAN	1	Following authors make substantial contributions to conception and design, and/or acquisition of data, and/or analysis and interpretation of data|Following authors participate in drafting the article or revising it critically for important intellectual content|Following authors give final approval of the version to be submitted and any revised version	Following authors give final approval of the version to be submitted and any revised version	Wrote the paper	Writing - Review & Editing	YES
5597174	28975908	All authors	2	executed the study and analyzed the results	executed the study and analyzed the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5597174	28975908	Andrea R. Pfalzgraf	2	conceived the study and designed the survey|provided revisions/comments	conceived the study and designed the survey	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
5597174	28975908	Andrea R. Pfalzgraf	2	conceived the study and designed the survey|provided revisions/comments	provided revisions/comments	Wrote the paper	Writing - Review & Editing	YES
5597174	28975908	Jordan R. Covvey	2	conceived the study and designed the survey	conceived the study and designed the survey	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
5597174	28975908	Peter P. Cohron	2	provided revisions/comments	provided revisions/comments	Wrote the paper	Writing - Review & Editing	YES
4672396	26643463	AAm	2	provided inputs to the first draft	provided inputs to the first draft	Wrote the paper	Writing - Original Draft	YES
4672396	26643463	AAr	2	provided feedback on the outline and substantially strengthened the first draft	provided feedback on the outline and substantially strengthened the first draft	Wrote the paper	Writing - Original Draft	YES
4672396	26643463	All authors	2	responded to the comments of the reviewers|also reviewed and agreed to the contents of the revised final draft	responded to the comments of the reviewers	-	-	NO
4672396	26643463	All authors	2	responded to the comments of the reviewers|also reviewed and agreed to the contents of the revised final draft	also reviewed and agreed to the contents of the revised final draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4672396	26643463	JF	2	contributed to the development of the outline of the paper and provided inputs to the first draft	contributed to the development of the outline of the paper and provided inputs to the first draft	Wrote the paper	Writing - Original Draft	YES
4672396	26643463	VC	2	conceived the paper, developed the outline and prepared the first draft	conceived the paper, developed the outline and prepared the first draft	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5021707	27656281	Case Report	2	concept and design, literature review, writing the paper, editing the paper, final submission of the paper|concept and design, literature review, writing the paper, editing the paper, final submission of the paper|concept and design, literature review, writing the paper, editing the paper, final submission of the paper|concept and design, literature review, writing the paper, editing the paper, final submission of the paper|concept and design, literature review, writing the paper, editing the paper, final submission of the paper	concept and design, literature review, writing the paper, editing the paper, final submission of the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5021707	27656281	Case Report	2	concept and design, literature review, writing the paper, editing the paper, final submission of the paper|concept and design, literature review, writing the paper, editing the paper, final submission of the paper|concept and design, literature review, writing the paper, editing the paper, final submission of the paper|concept and design, literature review, writing the paper, editing the paper, final submission of the paper|concept and design, literature review, writing the paper, editing the paper, final submission of the paper	concept and design, literature review, writing the paper, editing the paper, final submission of the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5021707	27656281	Case Report	2	concept and design, literature review, writing the paper, editing the paper, final submission of the paper|concept and design, literature review, writing the paper, editing the paper, final submission of the paper|concept and design, literature review, writing the paper, editing the paper, final submission of the paper|concept and design, literature review, writing the paper, editing the paper, final submission of the paper|concept and design, literature review, writing the paper, editing the paper, final submission of the paper	concept and design, literature review, writing the paper, editing the paper, final submission of the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5021707	27656281	Case Report	2	concept and design, literature review, writing the paper, editing the paper, final submission of the paper|concept and design, literature review, writing the paper, editing the paper, final submission of the paper|concept and design, literature review, writing the paper, editing the paper, final submission of the paper|concept and design, literature review, writing the paper, editing the paper, final submission of the paper|concept and design, literature review, writing the paper, editing the paper, final submission of the paper	concept and design, literature review, writing the paper, editing the paper, final submission of the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5021707	27656281	Case Report	2	concept and design, literature review, writing the paper, editing the paper, final submission of the paper|concept and design, literature review, writing the paper, editing the paper, final submission of the paper|concept and design, literature review, writing the paper, editing the paper, final submission of the paper|concept and design, literature review, writing the paper, editing the paper, final submission of the paper|concept and design, literature review, writing the paper, editing the paper, final submission of the paper	concept and design, literature review, writing the paper, editing the paper, final submission of the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5524832	28791036	AC	PLoS52	designed research	designed research	Conceived and designed the experiments	Methodology	YES
5524832	28791036	APa	PLoS52	performed research and analyzed data	performed research and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5524832	28791036	APe	PLoS52	performed research and analyzed data	performed research and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5524832	28791036	AV	PLoS52	designed research	designed research	Conceived and designed the experiments	Methodology	YES
5524832	28791036	All the authors	PLoS52	critically revised the article	critically revised the article	Wrote the paper	Writing - Review & Editing	YES
5524832	28791036	ED	PLoS52	performed research and analyzed data	performed research and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5524832	28791036	FC	PLoS52	designed research	designed research	Conceived and designed the experiments	Methodology	YES
5524832	28791036	LA	PLoS52	performed research and analyzed data	performed research and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5524832	28791036	MC	PLoS52	designed research|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
5524832	28791036	MC	PLoS52	designed research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5524832	28791036	SS	PLoS52	performed research and analyzed data	performed research and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5524832	28791036	VV	PLoS52	performed research and analyzed data	performed research and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6085556	29983350	BC	2	performed the statistical analyses	performed the statistical analyses	Analyzed the data	Formal analysis	YES
6085556	29983350	CB	2	conceived and designed the study|collected the clinical data	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6085556	29983350	CB	2	conceived and designed the study|collected the clinical data	collected the clinical data	Performed the experiments	Investigation	YES
6085556	29983350	DD	2	recruited the patients|collected the clinical data	recruited the patients	Performed the experiments	Investigation	YES
6085556	29983350	DD	2	recruited the patients|collected the clinical data	collected the clinical data	Performed the experiments	Investigation	YES
6085556	29983350	EAF	2	managed the trial	managed the trial	-	Project administration	YES
6085556	29983350	FM	2	performed the laboratory analyses	performed the laboratory analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6085556	29983350	JB	2	managed the trial	managed the trial	-	Project administration	YES
6085556	29983350	JN	2	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6085556	29983350	JS	2	managed the trial	managed the trial	-	Project administration	YES
6085556	29983350	LW	2	performed the laboratory analyses	performed the laboratory analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6085556	29983350	MC	2	performed the laboratory analyses	performed the laboratory analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6085556	29983350	MF	2	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6085556	29983350	NC	2	recruited the patients|collected the clinical data	recruited the patients	Performed the experiments	Investigation	YES
6085556	29983350	NC	2	recruited the patients|collected the clinical data	collected the clinical data	Performed the experiments	Investigation	YES
6085556	29983350	PT	2	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6085556	29983350	SD	2	conceived and designed the study|performed the statistical analyses	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6085556	29983350	SD	2	conceived and designed the study|performed the statistical analyses	performed the statistical analyses	Analyzed the data	Formal analysis	YES
6085556	29983350	SL	2	conceived and designed the study|managed the trial	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6085556	29983350	SL	2	conceived and designed the study|managed the trial	managed the trial	-	Project administration	YES
6085556	29983350	VB	2	managed the trial	managed the trial	-	Project administration	YES
6085556	29983350	WS	2	performed the statistical analyses	performed the statistical analyses	Analyzed the data	Formal analysis	YES
5597175	28975909	Agnieska Skowron	2	helped with distribution of the survey	helped with distribution of the survey	Performed the experiments	Investigation	YES
5597175	28975909	Annie Marcincal	2	helped with distribution of the survey	helped with distribution of the survey	Performed the experiments	Investigation	YES
5597175	28975909	Antonio Sanchez Pozo	2	developed the questionnaire|helped with distribution of the survey|provided useful criticism and suggestions during revision of the manuscript	developed the questionnaire	-	-	NO
5597175	28975909	Antonio Sanchez Pozo	2	developed the questionnaire|helped with distribution of the survey|provided useful criticism and suggestions during revision of the manuscript	helped with distribution of the survey	Performed the experiments	Investigation	YES
5597175	28975909	Antonio Sanchez Pozo	2	developed the questionnaire|helped with distribution of the survey|provided useful criticism and suggestions during revision of the manuscript	provided useful criticism and suggestions during revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5597175	28975909	Borut Bozic	2	helped with distribution of the survey	helped with distribution of the survey	Performed the experiments	Investigation	YES
5597175	28975909	Constantin Mircioiu	2	played a major role in the statistical analyses of the data	played a major role in the statistical analyses of the data	Analyzed the data	Formal analysis	YES
5597175	28975909	Daisy Volmer	2	provided useful criticism and suggestions during revision of the manuscript	provided useful criticism and suggestions during revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5597175	28975909	Dimitrios Rekkas	2	developed the questionnaire|helped with distribution of the survey	developed the questionnaire	-	-	NO
5597175	28975909	Dimitrios Rekkas	2	developed the questionnaire|helped with distribution of the survey	helped with distribution of the survey	Performed the experiments	Investigation	YES
5597175	28975909	Jamie Wilkinson	2	played a major role in distributing the survey to community pharmacists	played a major role in distributing the survey to community pharmacists	Performed the experiments	Investigation	YES
5597175	28975909	Jeffrey Atkinson	2	designed, constructed, ran and analysed the survey and wrote the paper	designed, constructed, ran and analysed the survey and wrote the paper	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5597175	28975909	Jouni Hirvonen	2	helped with distribution of the survey	helped with distribution of the survey	Performed the experiments	Investigation	YES
5597175	28975909	Kristien De Paepe	2	ran the phar-qa consortium|provided useful criticism and suggestions during revision of the manuscript	ran the phar-qa consortium	Performed the experiments	Investigation	YES
5597175	28975909	Kristien De Paepe	2	ran the phar-qa consortium|provided useful criticism and suggestions during revision of the manuscript	provided useful criticism and suggestions during revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5594459	28893277	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5594459	28893277	EJA	2	wrote and edited the manuscript, as well as created the figures	wrote and edited the manuscript, as well as created the figures	Wrote the paper	Visualization|Writing - Original Draft|Writing - Review & Editing	YES
5594459	28893277	GPK	2	edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5594459	28893277	TR	2	wrote and edited the manuscript, as well as created the figures	wrote and edited the manuscript, as well as created the figures	Wrote the paper	Visualization|Writing - Original Draft|Writing - Review & Editing	YES
5594459	28893277	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
4610660	26543310	AMS	2	contributed in designing and conducting the study|rechecked the statistical analysis and prepared the manuscript	contributed in designing and conducting the study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4610660	26543310	AMS	2	contributed in designing and conducting the study|rechecked the statistical analysis and prepared the manuscript	rechecked the statistical analysis and prepared the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
4610660	26543310	AY	2	contributed in designing and conducting the study	contributed in designing and conducting the study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4610660	26543310	All authors	2	have assisted in preparation of the manuscript and have read and approved the content of the manuscript and are accountable for all aspects of the work	have assisted in preparation of the manuscript and have read and approved the content of the manuscript and are accountable for all aspects of the work	Wrote the paper	Writing - Original Draft	YES
4610660	26543310	FS	2	contributed in designing and conducting the study	contributed in designing and conducting the study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4610660	26543310	HH	2	collected the data	collected the data	Performed the experiments	Investigation	YES
4610660	26543310	NEM	2	contributed in designing and conducting the study|rechecked the statistical analysis and prepared the manuscript	contributed in designing and conducting the study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4610660	26543310	NEM	2	contributed in designing and conducting the study|rechecked the statistical analysis and prepared the manuscript	rechecked the statistical analysis and prepared the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
4610660	26543310	ZF	2	helped in data analysis	helped in data analysis	Analyzed the data	Formal analysis	YES
5259817	28155652	EP	2	conceived the original idea of this study, participated in its design and coordination, and wrote sections of the manuscript	conceived the original idea of this study, participated in its design and coordination, and wrote sections of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
5259817	28155652	HK	2	carried out the experiments and provided input on drafts of the manuscript	carried out the experiments and provided input on drafts of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5259817	28155652	HL	2	carried out the experiments and drafted the manuscript	carried out the experiments and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5259817	28155652	K-BH	2	conceived the original idea of this study, participated in its design and coordination, and wrote sections of the manuscript	conceived the original idea of this study, participated in its design and coordination, and wrote sections of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
5259817	28155652	S-WL	2	provided the experimental data and wrote sections of the manuscript	provided the experimental data and wrote sections of the manuscript	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Original Draft	YES
5259817	28155652	YSJ	2	carried out the experiments and provided input on drafts of the manuscript	carried out the experiments and provided input on drafts of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4405207	25897806	A-NL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405207	25897806	C-SP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405207	25897806	C-SP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405207	25897806	C-SP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405207	25897806	H-KP	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405207	25897806	H-KP	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405207	25897806	H-KP	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405207	25897806	HL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405207	25897806	JR	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405207	25897806	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405207	25897806	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405207	25897806	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405207	25897806	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405207	25897806	YL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4672397	26643454	All authors	2	drafted sections of the manuscript	drafted sections of the manuscript	Wrote the paper	Writing - Original Draft	YES
4672397	26643454	RH	2	revised and edited the manuscript and all authors critically reviewed and provided recommended editing and alterations to the manuscript	revised and edited the manuscript and all authors critically reviewed and provided recommended editing and alterations to the manuscript	Wrote the paper	Writing - Review & Editing	YES
5629191	28983840	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5021709	27656280	Anastasios Angelou	7	study design, data collections, data analysis, writing	study design, data collections, data analysis, writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology	YES
5021709	27656280	Apostolos Papalois	7	data analysis	data analysis	Analyzed the data	Formal analysis	YES
5021709	27656280	Efstathios Antoniou	7	study design, data analysis, writing	study design, data analysis, writing	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology	YES
5021709	27656280	Emmanouil Pikoulis	7	study design, data analysis, writing	study design, data analysis, writing	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology	YES
5021709	27656280	Georgios Antonios Margonis	7	study design, data collections, data analysis, writing	study design, data collections, data analysis, writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology	YES
5021709	27656280	Ioannis Karavokyros	7	data analysis, writing	data analysis, writing	Analyzed the data|Wrote the paper	Formal analysis	YES
5021709	27656280	Paraskevi Argiri	7	data collections, data analysis	data collections, data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5021709	27656280	Pikouli Anastasia	7	data collections	data collections	Performed the experiments	Investigation	YES
6116353	30077721	CC	1	Study design	Study design	Conceived and designed the experiments	Methodology	YES
6116353	30077721	DW	1	Study design|Performed analyses|Wrote first draft	Study design	Conceived and designed the experiments	Methodology	YES
6116353	30077721	DW	1	Study design|Performed analyses|Wrote first draft	Performed analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6116353	30077721	DW	1	Study design|Performed analyses|Wrote first draft	Wrote first draft	Wrote the paper	Writing - Original Draft	YES
6116353	30077721	JD	1	Study design|Performed analyses|Wrote first draft	Study design	Conceived and designed the experiments	Methodology	YES
6116353	30077721	JD	1	Study design|Performed analyses|Wrote first draft	Performed analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6116353	30077721	JD	1	Study design|Performed analyses|Wrote first draft	Wrote first draft	Wrote the paper	Writing - Original Draft	YES
6116353	30077721	TW	1	Wrote first draft	Wrote first draft	Wrote the paper	Writing - Original Draft	YES
6116353	30077721	all authors	1	Critical review of manuscript	Critical review of manuscript	Wrote the paper	Writing - Review & Editing	YES
4477065	26180786	Chuanjun Zhuo	2	contributed equally to the paper	contributed equally to the paper	-	-	NO
4477065	26180786	Yongjie Xu	2	contributed equally to the paper	contributed equally to the paper	-	-	NO
5594471	28893274	Both authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5594471	28893274	KAH	2	wrote and approved the manuscript	wrote and approved the manuscript	Wrote the paper	Writing - Original Draft	YES
5594471	28893274	MDG	2	wrote and approved the manuscript	wrote and approved the manuscript	Wrote the paper	Writing - Original Draft	YES
5594471	28893274	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5524833	28791037	HW	PLoS5	Generated the plant material	Generated the plant material	Performed the experiments	Investigation	YES
5524833	28791037	JB	PLoS5	Generated the plant material	Generated the plant material	Performed the experiments	Investigation	YES
5524833	28791037	MK	PLoS5	Conceived and designed the project and experiments|Generated the plant material|Performed the immunodetection experiments|Analyzed the data|Wrote the paper	Conceived and designed the project and experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5524833	28791037	MK	PLoS5	Conceived and designed the project and experiments|Generated the plant material|Performed the immunodetection experiments|Analyzed the data|Wrote the paper	Generated the plant material	Performed the experiments	Investigation	YES
5524833	28791037	MK	PLoS5	Conceived and designed the project and experiments|Generated the plant material|Performed the immunodetection experiments|Analyzed the data|Wrote the paper	Performed the immunodetection experiments	Performed the experiments	Investigation	YES
5524833	28791037	MK	PLoS5	Conceived and designed the project and experiments|Generated the plant material|Performed the immunodetection experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5524833	28791037	MK	PLoS5	Conceived and designed the project and experiments|Generated the plant material|Performed the immunodetection experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5524833	28791037	MM	PLoS5	Performed the clone dna sequences comparison	Performed the clone dna sequences comparison	Performed the experiments	Investigation	YES
5021784	27656282	All authors	2	in this manuscript contributed to the interpretation of data, and drafting and writing of this manuscript	in this manuscript contributed to the interpretation of data, and drafting and writing of this manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
5021784	27656282	ES	2	were engaged in patients care in his hospital coarse including surgery under the	were engaged in patients care in his hospital coarse including surgery under the	Performed the experiments	Investigation	YES
5021784	27656282	HH	2	were engaged in patients care in his hospital coarse including surgery under the	were engaged in patients care in his hospital coarse including surgery under the	Performed the experiments	Investigation	YES
5021784	27656282	HT	2	were engaged in patients care in his hospital coarse including surgery under the|supervised the s care in his hospital coarse including surgery under the	were engaged in patients care in his hospital coarse including surgery under the	Performed the experiments	Investigation	YES
5021784	27656282	HT	2	were engaged in patients care in his hospital coarse including surgery under the|supervised the s care in his hospital coarse including surgery under the	supervised the s care in his hospital coarse including surgery under the	Performed the experiments	Investigation|Supervision	YES
5021784	27656282	JY	2	supervised the s care in his hospital coarse including surgery under the	supervised the s care in his hospital coarse including surgery under the	Performed the experiments	Investigation|Supervision	YES
5021784	27656282	KH	2	supervised the s care in his hospital coarse including surgery under the	supervised the s care in his hospital coarse including surgery under the	Performed the experiments	Investigation|Supervision	YES
5021784	27656282	KK	2	were engaged in patients care in his hospital coarse including surgery under the	were engaged in patients care in his hospital coarse including surgery under the	Performed the experiments	Investigation	YES
5021784	27656282	KY	2	were engaged in patients care in his hospital coarse including surgery under the	were engaged in patients care in his hospital coarse including surgery under the	Performed the experiments	Investigation	YES
5021784	27656282	NI	2	were engaged in patients care in his hospital coarse including surgery under the	were engaged in patients care in his hospital coarse including surgery under the	Performed the experiments	Investigation	YES
5021784	27656282	SA	2	were engaged in patients care in his hospital coarse including surgery under the	were engaged in patients care in his hospital coarse including surgery under the	Performed the experiments	Investigation	YES
5021784	27656282	SH	2	were engaged in patients care in his hospital coarse including surgery under the	were engaged in patients care in his hospital coarse including surgery under the	Performed the experiments	Investigation	YES
4405209	25898225	AI	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405209	25898225	AI	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405209	25898225	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405209	25898225	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405209	25898225	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405209	25898225	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405209	25898225	HS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405209	25898225	HS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405209	25898225	KI	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405209	25898225	KI	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405209	25898225	KK	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405209	25898225	KK	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405209	25898225	KY	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405209	25898225	KY	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405209	25898225	T. Yamamoto	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4405209	25898225	T. Yamamoto	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4405209	25898225	T. Yoshida	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4405209	25898225	T. Yoshida	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4405209	25898225	YT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405209	25898225	YT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405209	25898225	YT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405209	25898225	YT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5594475	28893281	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5594475	28893281	DEK	2	provided supervision and edited the manuscript	provided supervision and edited the manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
5594475	28893281	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5594475	28893281	all authors	2	reviewed the article before submission	reviewed the article before submission	Wrote the paper	Writing - Review & Editing	YES
5259856	28155669	AAY	2	were involved in purification and analysis of peroxisomes|wrote the manuscript	were involved in purification and analysis of peroxisomes	Performed the experiments	Investigation	YES
5259856	28155669	AAY	2	were involved in purification and analysis of peroxisomes|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5259856	28155669	AOB	2	performed bioinformatics work|wrote the manuscript	performed bioinformatics work	Performed the experiments	Formal analysis|Investigation	YES
5259856	28155669	AOB	2	performed bioinformatics work|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5259856	28155669	AP	2	performed confocal microscopy experiments	performed confocal microscopy experiments	Performed the experiments	Investigation	YES
5259856	28155669	IVK	2	designed the study|were involved in purification and analysis of peroxisomes	designed the study	Conceived and designed the experiments	Methodology	YES
5259856	28155669	IVK	2	designed the study|were involved in purification and analysis of peroxisomes	were involved in purification and analysis of peroxisomes	Performed the experiments	Investigation	YES
5259856	28155669	JHW	2	were involved in purification and analysis of peroxisomes	were involved in purification and analysis of peroxisomes	Performed the experiments	Investigation	YES
5259856	28155669	MK	2	were involved in purification and analysis of peroxisomes|generated microarray data|performed confocal microscopy experiments	were involved in purification and analysis of peroxisomes	Performed the experiments	Investigation	YES
5259856	28155669	MK	2	were involved in purification and analysis of peroxisomes|generated microarray data|performed confocal microscopy experiments	generated microarray data	Performed the experiments	Investigation	YES
5259856	28155669	MK	2	were involved in purification and analysis of peroxisomes|generated microarray data|performed confocal microscopy experiments	performed confocal microscopy experiments	Performed the experiments	Investigation	YES
5622347	28970446	Jeffrey Atkinson	2	wrote the first manuscript and dealt with revisions	wrote the first manuscript and dealt with revisions	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5622347	28970446	Valentina Petkova	2	provided all the data and information and helped in the revisions of the manuscript	provided all the data and information and helped in the revisions of the manuscript	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Review & Editing	YES
4672398	26643461	MN	2	provided intellectual guidance and content at every step of the study and manuscript revisions	provided intellectual guidance and content at every step of the study and manuscript revisions	Wrote the paper	Supervision|Writing - Review & Editing	YES
4672398	26643461	RK	2	provided intellectual guidance and content at every step of the study and manuscript revisions	provided intellectual guidance and content at every step of the study and manuscript revisions	Wrote the paper	Supervision|Writing - Review & Editing	YES
4672398	26643461	SG	2	conceptualized and designed the study and provided intellectual guidance and content at every step of the study and manuscript revisions	conceptualized and designed the study and provided intellectual guidance and content at every step of the study and manuscript revisions	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Supervision|Writing - Review & Editing	YES
4672398	26643461	SK	2	led data collection, analysis and manuscript writing	led data collection, analysis and manuscript writing	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5021796	27656283	All authors	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
5526064	28791040	BJ	2	contributed to write up and analysis	contributed to write up and analysis	Wrote the paper	-	YES
5526064	28791040	BW	2	contributed to study design, data collection, analysis and write up	contributed to study design, data collection, analysis and write up	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources	YES
5526064	28791040	LC-U	2	contributed to write up and analysis	contributed to write up and analysis	Wrote the paper	-	YES
5526064	28791040	RU	2	contributed to study design, data collection, analysis and write up	contributed to study design, data collection, analysis and write up	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources	YES
5638767	29027157	All authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5638767	29027157	Both authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5638767	29027157	DKEB	2	both contributed equally in writing this review	both contributed equally in writing this review	Wrote the paper	Writing - Review & Editing	YES
5638767	29027157	NF	2	both contributed equally in writing this review	both contributed equally in writing this review	Wrote the paper	Writing - Review & Editing	YES
4405264	25897782	BWS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405264	25897782	CWJ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405264	25897782	CWJ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405264	25897782	CWJ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405264	25897782	HMW	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405264	25897782	KKS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405264	25897782	PSW	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405264	25897782	PSW	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405264	25897782	TYW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405264	25897782	TYW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405264	25897782	TYW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405264	25897782	TYW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405264	25897782	YTW	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405264	25897782	YTW	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5024141	27668078	All authors	2	contributed equally to the study design, data collection, analysis/interpretation, writing and drafting of this manuscript	contributed equally to the study design, data collection, analysis/interpretation, writing and drafting of this manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
5594480	28893272	Both authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5594480	28893272	HIV	2	vaccine, and wrote the article	vaccine, and wrote the article	Wrote the paper	Writing - Original Draft	YES
5594480	28893272	YG	2	conducted research on immune responses	conducted research on immune responses	Performed the experiments	Investigation	YES
5526843	28798763	PH	2	wrote the manuscript jointly	wrote the manuscript jointly	Wrote the paper	Writing - Original Draft	YES
5526843	28798763	SG	2	wrote the manuscript jointly|designed the figure	wrote the manuscript jointly	Wrote the paper	Writing - Original Draft	YES
5526843	28798763	SG	2	wrote the manuscript jointly|designed the figure	designed the figure	Conceived and designed the experiments	Visualization	YES
5622348	28970448	A.M.	2	planned the study, analysed the results, wrote and edited the paper	planned the study, analysed the results, wrote and edited the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5622348	28970448	M.D.	2	wrote and edited the paper	wrote and edited the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5622348	28970448	VM	2	analysed the results, wrote and edited the paper	analysed the results, wrote and edited the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
6197330	30266295	BDW	CRediT	Data analysis|Writing - review & editing	Data analysis	Analyzed the data	Formal analysis	YES
6197330	30266295	BDW	CRediT	Data analysis|Writing - review & editing	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
6197330	30266295	BG	CRediT	Investigation|Data analysis	Investigation	Performed the experiments	Investigation	YES
6197330	30266295	BG	CRediT	Investigation|Data analysis	Data analysis	Analyzed the data	Formal analysis	YES
6197330	30266295	BL	CRediT	Funding acquisition|Resources|Supervision	Funding acquisition	-	Funding acquisition	YES
6197330	30266295	BL	CRediT	Funding acquisition|Resources|Supervision	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6197330	30266295	BL	CRediT	Funding acquisition|Resources|Supervision	Supervision	-	Supervision	YES
6197330	30266295	FM	CRediT	Funding acquisition|Resources|Supervision|Writing - review & editing	Funding acquisition	-	Funding acquisition	YES
6197330	30266295	FM	CRediT	Funding acquisition|Resources|Supervision|Writing - review & editing	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6197330	30266295	FM	CRediT	Funding acquisition|Resources|Supervision|Writing - review & editing	Supervision	-	Supervision	YES
6197330	30266295	FM	CRediT	Funding acquisition|Resources|Supervision|Writing - review & editing	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
6197330	30266295	GP	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
6197330	30266295	MW	CRediT	Conceptualization|Study design|Investigation|Data analysis|Funding acquisition|Writing - original draft|Writing - review & editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6197330	30266295	MW	CRediT	Conceptualization|Study design|Investigation|Data analysis|Funding acquisition|Writing - original draft|Writing - review & editing	Study design	Conceived and designed the experiments	Methodology	YES
6197330	30266295	MW	CRediT	Conceptualization|Study design|Investigation|Data analysis|Funding acquisition|Writing - original draft|Writing - review & editing	Investigation	Performed the experiments	Investigation	YES
6197330	30266295	MW	CRediT	Conceptualization|Study design|Investigation|Data analysis|Funding acquisition|Writing - original draft|Writing - review & editing	Data analysis	Analyzed the data	Formal analysis	YES
6197330	30266295	MW	CRediT	Conceptualization|Study design|Investigation|Data analysis|Funding acquisition|Writing - original draft|Writing - review & editing	Funding acquisition	-	Funding acquisition	YES
6197330	30266295	MW	CRediT	Conceptualization|Study design|Investigation|Data analysis|Funding acquisition|Writing - original draft|Writing - review & editing	Writing - original draft	Wrote the paper	Writing - Original Draft	YES
6197330	30266295	MW	CRediT	Conceptualization|Study design|Investigation|Data analysis|Funding acquisition|Writing - original draft|Writing - review & editing	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
6197330	30266295	MY	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
6197330	30266295	NK	CRediT	Conceptualization|Study design|Funding acquisition|Resources|Supervision|Writing - original draft|Writing - review & editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6197330	30266295	NK	CRediT	Conceptualization|Study design|Funding acquisition|Resources|Supervision|Writing - original draft|Writing - review & editing	Study design	Conceived and designed the experiments	Methodology	YES
6197330	30266295	NK	CRediT	Conceptualization|Study design|Funding acquisition|Resources|Supervision|Writing - original draft|Writing - review & editing	Funding acquisition	-	Funding acquisition	YES
6197330	30266295	NK	CRediT	Conceptualization|Study design|Funding acquisition|Resources|Supervision|Writing - original draft|Writing - review & editing	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6197330	30266295	NK	CRediT	Conceptualization|Study design|Funding acquisition|Resources|Supervision|Writing - original draft|Writing - review & editing	Supervision	-	Supervision	YES
6197330	30266295	NK	CRediT	Conceptualization|Study design|Funding acquisition|Resources|Supervision|Writing - original draft|Writing - review & editing	Writing - original draft	Wrote the paper	Writing - Original Draft	YES
6197330	30266295	NK	CRediT	Conceptualization|Study design|Funding acquisition|Resources|Supervision|Writing - original draft|Writing - review & editing	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
6197330	30266295	RH	CRediT	Funding acquisition|Resources|Supervision	Funding acquisition	-	Funding acquisition	YES
6197330	30266295	RH	CRediT	Funding acquisition|Resources|Supervision	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6197330	30266295	RH	CRediT	Funding acquisition|Resources|Supervision	Supervision	-	Supervision	YES
6197330	30266295	TA	CRediT	Resources|Supervision	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6197330	30266295	TA	CRediT	Resources|Supervision	Supervision	-	Supervision	YES
6197330	30266295	TD	CRediT	Funding acquisition|Resources|Supervision|Writing - review & editing	Funding acquisition	-	Funding acquisition	YES
6197330	30266295	TD	CRediT	Funding acquisition|Resources|Supervision|Writing - review & editing	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6197330	30266295	TD	CRediT	Funding acquisition|Resources|Supervision|Writing - review & editing	Supervision	-	Supervision	YES
6197330	30266295	TD	CRediT	Funding acquisition|Resources|Supervision|Writing - review & editing	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
6197330	30266295	TG	CRediT	Study design|Investigation|Resources	Study design	Conceived and designed the experiments	Methodology	YES
6197330	30266295	TG	CRediT	Study design|Investigation|Resources	Investigation	Performed the experiments	Investigation	YES
6197330	30266295	TG	CRediT	Study design|Investigation|Resources	Resources	Contributed reagents/materials/analysis tools	Resources	YES
4672399	26643457	AC	2	contributed to the conceptualization and design of the study	contributed to the conceptualization and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4672399	26643457	AK	2	contributed to the conceptualization and design of the study|wrote the first draft of the manuscript and all co-authors critically reviewed and revised the manuscript for intellectual content	contributed to the conceptualization and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4672399	26643457	AK	2	contributed to the conceptualization and design of the study|wrote the first draft of the manuscript and all co-authors critically reviewed and revised the manuscript for intellectual content	wrote the first draft of the manuscript and all co-authors critically reviewed and revised the manuscript for intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4672399	26643457	AN	2	conducted the statistical analyses	conducted the statistical analyses	Analyzed the data	Formal analysis	YES
4672399	26643457	AdP	2	contributed to the conceptualization and design of the study	contributed to the conceptualization and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4672399	26643457	GC	2	conducted the statistical analyses	conducted the statistical analyses	Analyzed the data	Formal analysis	YES
4672399	26643457	JTP	2	contributed to the conceptualization and design of the study	contributed to the conceptualization and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4672399	26643457	KB	2	contributed to the conceptualization and design of the study	contributed to the conceptualization and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4672399	26643457	KPB	2	contributed to the conceptualization and design of the study	contributed to the conceptualization and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4672399	26643457	ML	2	contributed to the conceptualization and design of the study	contributed to the conceptualization and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4672399	26643457	NO	2	contributed to the conceptualization and design of the study	contributed to the conceptualization and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4672399	26643457	PS	2	conducted the statistical analyses	conducted the statistical analyses	Analyzed the data	Formal analysis	YES
4672399	26643457	RSH	2	contributed to the conceptualization and design of the study	contributed to the conceptualization and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4672399	26643457	SP	2	contributed to the conceptualization and design of the study	contributed to the conceptualization and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4672399	26643457	VJN	2	contributed to the conceptualization and design of the study	contributed to the conceptualization and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4672399	26643457	WT	2	contributed to the conceptualization and design of the study	contributed to the conceptualization and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5026691	27668079	CH	7	main author	main author	Wrote the paper	Writing - Original Draft	YES
5026691	27668079	CW	7	reviewed article, provided comments, repeated search and appraisals	reviewed article, provided comments, repeated search and appraisals	Wrote the paper	Writing - Review & Editing	YES
5026691	27668079	SG	7	reviewed article, provided comments	reviewed article, provided comments	Wrote the paper	Writing - Review & Editing	YES
5030320	27672438	AK	2	conceived the study, participated in its design and coordination, and drafted the manuscript	conceived the study, participated in its design and coordination, and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
5030320	27672438	AM	2	helped to draft the manuscript	helped to draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5030320	27672438	IM	2	helped to draft the manuscript	helped to draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5030320	27672438	KK	2	helped to draft the manuscript	helped to draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5030320	27672438	OO	2	helped to draft the manuscript	helped to draft the manuscript	Wrote the paper	Writing - Original Draft	YES
4405267	25898323	BWW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405267	25898323	BWW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4405267	25898323	BWW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405267	25898323	HML	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405267	25898323	KGS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405267	25898323	KGS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405267	25898323	WPC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405267	25898323	WPC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405267	25898323	WPC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405267	25898323	WPC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405267	25898323	WPC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5594498	28893268	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5594498	28893268	FAP	2	conceived and designed research, acquired funding, supervised and advised research, and revised the review	conceived and designed research, acquired funding, supervised and advised research, and revised the review	Conceived and designed the experiments|Wrote the paper	Conceptualization|Funding acquisition|Methodology|Supervision|Writing - Review & Editing	YES
5594498	28893268	HL	2	conducted research and wrote the review	conducted research and wrote the review	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5594498	28893268	ML	2	conceived and designed research, acquired funding, supervised and advised research, and revised the review	conceived and designed research, acquired funding, supervised and advised research, and revised the review	Conceived and designed the experiments|Wrote the paper	Conceptualization|Funding acquisition|Methodology|Supervision|Writing - Review & Editing	YES
5594498	28893268	RWO	2	conducted research and wrote the review	conducted research and wrote the review	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6197429	30316868	CY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6197429	30316868	CY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
6197429	30316868	CY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
6197429	30316868	DDR	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6197429	30316868	DDR	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6197429	30316868	KH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
6197429	30316868	MM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6197429	30316868	MM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
6197429	30316868	MM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
6197429	30316868	MM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6197429	30316868	MN	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
6197429	30316868	NS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
6197429	30316868	SML	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5622349	28970449	A.A.N.	2	designed the methodology and wrote the manuscript|revised and edited the manuscript in response to reviewers comments	designed the methodology and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5622349	28970449	A.A.N.	2	designed the methodology and wrote the manuscript|revised and edited the manuscript in response to reviewers comments	revised and edited the manuscript in response to reviewers comments	Wrote the paper	Writing - Review & Editing	YES
5622349	28970449	M.S.A.G.	2	jointly conceived the idea|jointly designed and validated the questionnaire	jointly conceived the idea	Conceived and designed the experiments	Conceptualization	YES
5622349	28970449	M.S.A.G.	2	jointly conceived the idea|jointly designed and validated the questionnaire	jointly designed and validated the questionnaire	Conceived and designed the experiments|Performed the experiments	Validation	YES
5622349	28970449	R.A.A.J.	2	jointly conceived the idea|jointly designed and validated the questionnaire	jointly conceived the idea	Conceived and designed the experiments	Conceptualization	YES
5622349	28970449	R.A.A.J.	2	jointly conceived the idea|jointly designed and validated the questionnaire	jointly designed and validated the questionnaire	Conceived and designed the experiments|Performed the experiments	Validation	YES
5622349	28970449	S.A.	2	jointly conceived the idea|conducted the project|jointly designed and validated the questionnaire	jointly conceived the idea	Conceived and designed the experiments	Conceptualization	YES
5622349	28970449	S.A.	2	jointly conceived the idea|conducted the project|jointly designed and validated the questionnaire	conducted the project	Performed the experiments	Investigation	YES
5622349	28970449	S.A.	2	jointly conceived the idea|conducted the project|jointly designed and validated the questionnaire	jointly designed and validated the questionnaire	Conceived and designed the experiments|Performed the experiments	Validation	YES
5673059	29105003	AY	2	contributed to the data interpretation and to the drafting and revisions of the manuscript	contributed to the data interpretation and to the drafting and revisions of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5673059	29105003	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5673059	29105003	Good Clinical Practice	2	were approved by the institutional review board or ethics committee of each trial centre	were approved by the institutional review board or ethics committee of each trial centre	-	-	NO
5673059	29105003	JE	2	contributed to the data interpretation and to the drafting and revisions of the manuscript	contributed to the data interpretation and to the drafting and revisions of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5673059	29105003	OL	2	performed the statistical analyses|contributed to the data interpretation and to the drafting and revisions of the manuscript	performed the statistical analyses	Analyzed the data	Formal analysis	YES
5673059	29105003	OL	2	performed the statistical analyses|contributed to the data interpretation and to the drafting and revisions of the manuscript	contributed to the data interpretation and to the drafting and revisions of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5673059	29105003	RM	2	contributed to the data interpretation and to the drafting and revisions of the manuscript	contributed to the data interpretation and to the drafting and revisions of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5673059	29105003	TS	2	contributed to the data interpretation and to the drafting and revisions of the manuscript	contributed to the data interpretation and to the drafting and revisions of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
4477099	26180791	Norbert Zentai	2	contributed equally to this work	contributed equally to this work	-	-	NO
4477099	26180791	Serena Fiocchi	2	contributed equally to this work	contributed equally to this work	-	-	NO
4672400	26643456	CRC	2	assisted with the background and editing of the paper	assisted with the background and editing of the paper	Wrote the paper	Writing - Review & Editing	YES
4672400	26643456	MJH	2	conceptualized the paper and wrote the manuscript	conceptualized the paper and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4672400	26643456	MM	2	contributed data and ideas for the structure of the paper	contributed data and ideas for the structure of the paper	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceptualization|Resources	YES
4672400	26643456	MN	2	contributed data and ideas for the structure of the paper	contributed data and ideas for the structure of the paper	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceptualization|Resources	YES
5259865	28155712	AV	PLoS52	conceived the research|helped with computational analysis|wrote the paper	conceived the research	Conceived and designed the experiments	Conceptualization	YES
5259865	28155712	AV	PLoS52	conceived the research|helped with computational analysis|wrote the paper	helped with computational analysis	Analyzed the data	Formal analysis	YES
5259865	28155712	AV	PLoS52	conceived the research|helped with computational analysis|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5259865	28155712	All the authors	PLoS52	checked and approved the manuscript	checked and approved the manuscript	Wrote the paper	Writing - Review & Editing	YES
5259865	28155712	SA	PLoS52	helped with experiments	helped with experiments	Performed the experiments	Investigation	YES
5259865	28155712	ST	PLoS52	conceived the research|helped with computational analysis|wrote the paper	conceived the research	Conceived and designed the experiments	Conceptualization	YES
5259865	28155712	ST	PLoS52	conceived the research|helped with computational analysis|wrote the paper	helped with computational analysis	Analyzed the data	Formal analysis	YES
5259865	28155712	ST	PLoS52	conceived the research|helped with computational analysis|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5259865	28155712	YK	PLoS52	conceived the research|performed experiments and computational analysis|wrote the paper	conceived the research	Conceived and designed the experiments	Conceptualization	YES
5259865	28155712	YK	PLoS52	conceived the research|performed experiments and computational analysis|wrote the paper	performed experiments and computational analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5259865	28155712	YK	PLoS52	conceived the research|performed experiments and computational analysis|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5259865	28155712	YS	PLoS52	performed rna seq experiments	performed rna seq experiments	Performed the experiments	Investigation	YES
5526896	28798764	CS	2	participated in the data analysis and interpretation	participated in the data analysis and interpretation	Analyzed the data	Formal analysis	YES
5526896	28798764	FF	2	participated in the data analysis and interpretation	participated in the data analysis and interpretation	Analyzed the data	Formal analysis	YES
5526896	28798764	HM	2	reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5526896	28798764	HW	2	participated in the data analysis and interpretation	participated in the data analysis and interpretation	Analyzed the data	Formal analysis	YES
5526896	28798764	KX	2	contributed to data acquisition	contributed to data acquisition	Performed the experiments	Investigation	YES
5526896	28798764	LC	2	performed the experiment, analyzed the data, and drafted the article	performed the experiment, analyzed the data, and drafted the article	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5526896	28798764	LL	2	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5526896	28798764	QL	2	performed the experiment, analyzed the data, and drafted the article	performed the experiment, analyzed the data, and drafted the article	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5526896	28798764	TL	2	contributed to data acquisition	contributed to data acquisition	Performed the experiments	Investigation	YES
5526896	28798764	XP	2	contributed to data acquisition	contributed to data acquisition	Performed the experiments	Investigation	YES
5526896	28798764	YZ	2	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5037117	27699003	Hamid Mohamadlou	7	Data collection, data analysis	Data collection, data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5037117	27699003	Jake Calvert	7	Study design, data collection, data analysis, writing. Uli Chettipally, Study design, review	Study design, data collection, data analysis, writing. Uli Chettipally, Study design, review	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Review & Editing	YES
5037117	27699003	Jana Hoffman	7	Study design, writing	Study design, writing	Conceived and designed the experiments|Wrote the paper	Methodology	YES
5037117	27699003	Melissa Jay	7	Data collection, data analysis	Data collection, data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5037117	27699003	Qingqing Mao	7	Data collection, data analysis	Data collection, data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5037117	27699003	Ritankar Das	7	Study design, editing	Study design, editing	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5037117	27699003	Thomas Desautels	7	Study design, data collection, data analysis, writing. Uli Chettipally, Study design, review	Study design, data collection, data analysis, writing. Uli Chettipally, Study design, review	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Review & Editing	YES
4405268	25898135	BZW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405268	25898135	MMG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405268	25898135	SDM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405268	25898135	SDM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405268	25898135	SDM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405268	25898135	WWL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405268	25898135	XL	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405268	25898135	XL	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405268	25898135	XL	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405268	25898135	XL	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405268	25898135	ZP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4405268	25898135	ZP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5037119	27699002	Adam Cristaudo	1	Study design|Data collections & data analysis|Writing	Study design	Conceived and designed the experiments	Methodology	YES
5037119	27699002	Adam Cristaudo	1	Study design|Data collections & data analysis|Writing	Data collections & data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5037119	27699002	Adam Cristaudo	1	Study design|Data collections & data analysis|Writing	Writing	Wrote the paper	-	YES
5037119	27699002	Rasika Hendahewa	1	Study design	Study design	Conceived and designed the experiments	Methodology	YES
5037119	27699002	Ryo Mizumoto	1	Data collections & data analysis|Writing	Data collections & data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5037119	27699002	Ryo Mizumoto	1	Data collections & data analysis|Writing	Writing	Wrote the paper	-	YES
5594512	28893288	Both authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5594512	28893288	JPR	2	participated in the drafting of the manuscript	participated in the drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
5594512	28893288	VM	2	participated in the drafting of the manuscript	participated in the drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
6197498	30249545	All authors	2	contributed to the conception and design of this project including acquisition, analysis, and interpretation of the data for publication|contributed to drafting of the work and revising it critically|provided final version of the work to be published|agree to be accountable for all aspects of the work and in ensuring that questions related to accuracy or integrity of any part of the work are appropriately investigated and resolved	contributed to the conception and design of this project including acquisition, analysis, and interpretation of the data for publication	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Methodology|Resources	YES
6197498	30249545	All authors	2	contributed to the conception and design of this project including acquisition, analysis, and interpretation of the data for publication|contributed to drafting of the work and revising it critically|provided final version of the work to be published|agree to be accountable for all aspects of the work and in ensuring that questions related to accuracy or integrity of any part of the work are appropriately investigated and resolved	contributed to drafting of the work and revising it critically	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6197498	30249545	All authors	2	contributed to the conception and design of this project including acquisition, analysis, and interpretation of the data for publication|contributed to drafting of the work and revising it critically|provided final version of the work to be published|agree to be accountable for all aspects of the work and in ensuring that questions related to accuracy or integrity of any part of the work are appropriately investigated and resolved	provided final version of the work to be published	-	-	NO
6197498	30249545	All authors	2	contributed to the conception and design of this project including acquisition, analysis, and interpretation of the data for publication|contributed to drafting of the work and revising it critically|provided final version of the work to be published|agree to be accountable for all aspects of the work and in ensuring that questions related to accuracy or integrity of any part of the work are appropriately investigated and resolved	agree to be accountable for all aspects of the work and in ensuring that questions related to accuracy or integrity of any part of the work are appropriately investigated and resolved	-	-	NO
4639353	26622080	All authors	2	have read and approved the content of the manuscript	have read and approved the content of the manuscript	-	-	NO
4639353	26622080	The authors	2	are liable for its content and for having participated in writing and reviewing the text, as well as approving the final version to be submitted	are liable for its content and for having participated in writing and reviewing the text, as well as approving the final version to be submitted	Wrote the paper	Writing - Review & Editing	YES
5622350	28970450	HB	2	supervised the study, including the development of the study and interview questions, data analysis and contributed to the manuscript preparation	supervised the study, including the development of the study and interview questions, data analysis and contributed to the manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Supervision|Writing - Original Draft	YES
5622350	28970450	RES	2	led the overall project, completed the literature review, designed the interview questions, led the interviews, undertook data analysis and led the manuscript preparation	led the overall project, completed the literature review, designed the interview questions, led the interviews, undertook data analysis and led the manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5622350	28970450	RSB	2	contributed to development of the interview questions and preparation of the manuscript	contributed to development of the interview questions and preparation of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4672401	26643464	AA	2	prepared the draft	prepared the draft	Wrote the paper	Writing - Original Draft	YES
5698240	29164495	All authors	2	have participated in contributing their outcomes and writing of this manuscript|have provided consent for this submission|read and approved the final manuscript	have participated in contributing their outcomes and writing of this manuscript	Wrote the paper	Writing - Original Draft	YES
5698240	29164495	All authors	2	have participated in contributing their outcomes and writing of this manuscript|have provided consent for this submission|read and approved the final manuscript	have provided consent for this submission	-	-	NO
5698240	29164495	All authors	2	have participated in contributing their outcomes and writing of this manuscript|have provided consent for this submission|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5526902	28798753	JG	PLoS52	helped with the performed most of the experiments with	helped with the performed most of the experiments with	Performed the experiments	Investigation	YES
5526902	28798753	LC	PLoS52	performed most of the experiments with|wrote the paper	performed most of the experiments with	Performed the experiments	Investigation	YES
5526902	28798753	LC	PLoS52	performed most of the experiments with|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5526902	28798753	XW	PLoS52	conceived of and designed the study|wrote the paper	conceived of and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5526902	28798753	XW	PLoS52	conceived of and designed the study|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5526902	28798753	YD	PLoS52	helped with the performed most of the experiments with	helped with the performed most of the experiments with	Performed the experiments	Investigation	YES
5526902	28798753	YG	PLoS52	helped with the performed most of the experiments with	helped with the performed most of the experiments with	Performed the experiments	Investigation	YES
5526902	28798753	ZH	PLoS52	helped with the performed most of the experiments with	helped with the performed most of the experiments with	Performed the experiments	Investigation	YES
5526902	28798753	ZQ	PLoS52	performed most of the experiments with|wrote the paper	performed most of the experiments with	Performed the experiments	Investigation	YES
5526902	28798753	ZQ	PLoS52	performed most of the experiments with|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5526902	28798753	ZW	PLoS52	helped with the performed most of the experiments with	helped with the performed most of the experiments with	Performed the experiments	Investigation	YES
5037211	27699001	Dr Riyadh	2	contributed in doing surgery, study concept or design, data collection, data analysis or interpretation, writing the paper, others	contributed in doing surgery, study concept or design, data collection, data analysis or interpretation, writing the paper, others	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
5622351	28970451	J.C.	2	conceived and designed the survey tool	conceived and designed the survey tool	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5622351	28970451	K.C.	2	conceived and designed the survey tool	conceived and designed the survey tool	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5622351	28970451	K.D.	2	coded and analyzed the data|wrote the initial draft of the paper with all authors contributing to the manuscript revisions	coded and analyzed the data	Analyzed the data	Data curation|Formal analysis	YES
5622351	28970451	K.D.	2	coded and analyzed the data|wrote the initial draft of the paper with all authors contributing to the manuscript revisions	wrote the initial draft of the paper with all authors contributing to the manuscript revisions	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5622351	28970451	W.P.	2	conceived and designed the survey tool|pilot tested and administered the survey|coded and analyzed the data	conceived and designed the survey tool	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5622351	28970451	W.P.	2	conceived and designed the survey tool|pilot tested and administered the survey|coded and analyzed the data	pilot tested and administered the survey	Performed the experiments	Investigation	YES
5622351	28970451	W.P.	2	conceived and designed the survey tool|pilot tested and administered the survey|coded and analyzed the data	coded and analyzed the data	Analyzed the data	Data curation|Formal analysis	YES
4405269	25898129	DAN	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4405269	25898129	DAN	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405269	25898129	DIC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4405269	25898129	DIC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405269	25898129	HS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Conceived and designed the analyses	Performed the experiments	Performed the experiments	Investigation	YES
4405269	25898129	HS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Conceived and designed the analyses	Analyzed the data	Analyzed the data	Formal analysis	YES
4405269	25898129	HS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Conceived and designed the analyses	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405269	25898129	HS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Conceived and designed the analyses	Conceived and designed the analyses	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
4405269	25898129	JDS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4405269	25898129	JDS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405269	25898129	MS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Conceived and designed the analyses	Performed the experiments	Performed the experiments	Investigation	YES
4405269	25898129	MS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Conceived and designed the analyses	Analyzed the data	Analyzed the data	Formal analysis	YES
4405269	25898129	MS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Conceived and designed the analyses	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405269	25898129	MS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Conceived and designed the analyses	Conceived and designed the analyses	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
4405269	25898129	PMR	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4405269	25898129	PMR	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405269	25898129	RMK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405269	25898129	RMK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405269	25898129	RMK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405269	25898129	RMK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405269	25898129	RMK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405269	25898129	SM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4405269	25898129	SM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5259951	28155655	BB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5259951	28155655	BB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5259951	28155655	IT	PLoS5	Sample preparation, dna extraction and array hybridization|Contributed reagents/materials/analysis tools	Sample preparation, dna extraction and array hybridization	Performed the experiments	Investigation	YES
5259951	28155655	IT	PLoS5	Sample preparation, dna extraction and array hybridization|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5259951	28155655	MW	PLoS5	Sample preparation, dna extraction and array hybridization|Contributed reagents/materials/analysis tools	Sample preparation, dna extraction and array hybridization	Performed the experiments	Investigation	YES
5259951	28155655	MW	PLoS5	Sample preparation, dna extraction and array hybridization|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5259951	28155655	RE	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5259951	28155655	RE	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5259951	28155655	SC	PLoS5	Conceived and designed the experiments|Sample preparation, dna extraction and array hybridization|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5259951	28155655	SC	PLoS5	Conceived and designed the experiments|Sample preparation, dna extraction and array hybridization|Contributed reagents/materials/analysis tools	Sample preparation, dna extraction and array hybridization	Performed the experiments	Investigation	YES
5259951	28155655	SC	PLoS5	Conceived and designed the experiments|Sample preparation, dna extraction and array hybridization|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5259951	28155655	UK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5259951	28155655	UK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5259951	28155655	VS	PLoS5	Contributed reagents/materials/analysis tools|Data handling and analysis	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5259951	28155655	VS	PLoS5	Contributed reagents/materials/analysis tools|Data handling and analysis	Data handling and analysis	Analyzed the data	Data curation|Formal analysis	YES
4672402	26643460	AW	2	conceived the study|designed the study|collected the data, and all authors interpreted the data|edited the draft	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4672402	26643460	AW	2	conceived the study|designed the study|collected the data, and all authors interpreted the data|edited the draft	designed the study	Conceived and designed the experiments	Methodology	YES
4672402	26643460	AW	2	conceived the study|designed the study|collected the data, and all authors interpreted the data|edited the draft	collected the data, and all authors interpreted the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4672402	26643460	AW	2	conceived the study|designed the study|collected the data, and all authors interpreted the data|edited the draft	edited the draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4672402	26643460	CL	2	edited the draft	edited the draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4672402	26643460	ETC	2	conceived the study|designed the study|collected the data, and all authors interpreted the data	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4672402	26643460	ETC	2	conceived the study|designed the study|collected the data, and all authors interpreted the data	designed the study	Conceived and designed the experiments	Methodology	YES
4672402	26643460	ETC	2	conceived the study|designed the study|collected the data, and all authors interpreted the data	collected the data, and all authors interpreted the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4672402	26643460	LO	2	conceived the study|designed the study|collected the data, and all authors interpreted the data|edited the draft	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4672402	26643460	LO	2	conceived the study|designed the study|collected the data, and all authors interpreted the data|edited the draft	designed the study	Conceived and designed the experiments	Methodology	YES
4672402	26643460	LO	2	conceived the study|designed the study|collected the data, and all authors interpreted the data|edited the draft	collected the data, and all authors interpreted the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4672402	26643460	LO	2	conceived the study|designed the study|collected the data, and all authors interpreted the data|edited the draft	edited the draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4672402	26643460	MJV	2	conceived the study|designed the study|collected the data, and all authors interpreted the data	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4672402	26643460	MJV	2	conceived the study|designed the study|collected the data, and all authors interpreted the data	designed the study	Conceived and designed the experiments	Methodology	YES
4672402	26643460	MJV	2	conceived the study|designed the study|collected the data, and all authors interpreted the data	collected the data, and all authors interpreted the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4672402	26643460	SB	2	conceived the study|designed the study|collected the data, and all authors interpreted the data|edited the draft	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4672402	26643460	SB	2	conceived the study|designed the study|collected the data, and all authors interpreted the data|edited the draft	designed the study	Conceived and designed the experiments	Methodology	YES
4672402	26643460	SB	2	conceived the study|designed the study|collected the data, and all authors interpreted the data|edited the draft	collected the data, and all authors interpreted the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4672402	26643460	SB	2	conceived the study|designed the study|collected the data, and all authors interpreted the data|edited the draft	edited the draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4672402	26643460	SM	2	designed the study|collected the data, and all authors interpreted the data|edited the draft	designed the study	Conceived and designed the experiments	Methodology	YES
4672402	26643460	SM	2	designed the study|collected the data, and all authors interpreted the data|edited the draft	collected the data, and all authors interpreted the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4672402	26643460	SM	2	designed the study|collected the data, and all authors interpreted the data|edited the draft	edited the draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4672402	26643460	SS	2	designed the study|collected the data, and all authors interpreted the data|edited the draft	designed the study	Conceived and designed the experiments	Methodology	YES
4672402	26643460	SS	2	designed the study|collected the data, and all authors interpreted the data|edited the draft	collected the data, and all authors interpreted the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4672402	26643460	SS	2	designed the study|collected the data, and all authors interpreted the data|edited the draft	edited the draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6197651	30268832	CHNC	PLoS5	Gathered the clinical sample and data	Gathered the clinical sample and data	Performed the experiments	Investigation	YES
6197651	30268832	DCJ	PLoS5	Analysed data|Wrote the manuscript	Analysed data	Analyzed the data	Formal analysis	YES
6197651	30268832	DCJ	PLoS5	Analysed data|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6197651	30268832	DLC	PLoS5	Gathered the clinical sample and data	Gathered the clinical sample and data	Performed the experiments	Investigation	YES
6197651	30268832	EB	PLoS5	Performed experiments	Performed experiments	Performed the experiments	Investigation	YES
6197651	30268832	JBTC	PLoS5	Conceived and designed the experiments|Performed experiments|Analysed data|Wrote the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6197651	30268832	JBTC	PLoS5	Conceived and designed the experiments|Performed experiments|Analysed data|Wrote the manuscript	Performed experiments	Performed the experiments	Investigation	YES
6197651	30268832	JBTC	PLoS5	Conceived and designed the experiments|Performed experiments|Analysed data|Wrote the manuscript	Analysed data	Analyzed the data	Formal analysis	YES
6197651	30268832	JBTC	PLoS5	Conceived and designed the experiments|Performed experiments|Analysed data|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6197651	30268832	JCM	PLoS5	Conceived and designed the experiments|Analysed data|Wrote the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6197651	30268832	JCM	PLoS5	Conceived and designed the experiments|Analysed data|Wrote the manuscript	Analysed data	Analyzed the data	Formal analysis	YES
6197651	30268832	JCM	PLoS5	Conceived and designed the experiments|Analysed data|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6197651	30268832	JDD	PLoS5	Conceived and designed the experiments|Performed experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6197651	30268832	JDD	PLoS5	Conceived and designed the experiments|Performed experiments	Performed experiments	Performed the experiments	Investigation	YES
6197651	30268832	KC	PLoS5	Conceived and designed the experiments|Analysed data|Wrote the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6197651	30268832	KC	PLoS5	Conceived and designed the experiments|Analysed data|Wrote the manuscript	Analysed data	Analyzed the data	Formal analysis	YES
6197651	30268832	KC	PLoS5	Conceived and designed the experiments|Analysed data|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6197651	30268832	NJD	PLoS5	Analysed data	Analysed data	Analyzed the data	Formal analysis	YES
6197651	30268832	RD	PLoS5	Gathered the clinical sample and data	Gathered the clinical sample and data	Performed the experiments	Investigation	YES
6197651	30268832	SF	PLoS5	Analysed data|Wrote the manuscript	Analysed data	Analyzed the data	Formal analysis	YES
6197651	30268832	SF	PLoS5	Analysed data|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6197651	30268832	SFGC	PLoS5	Gathered the clinical sample and data	Gathered the clinical sample and data	Performed the experiments	Investigation	YES
6197651	30268832	VCS	PLoS5	Performed experiments	Performed experiments	Performed the experiments	Investigation	YES
5526905	28798768	J-PZ	2	carried out mutant screening and validation experiments	carried out mutant screening and validation experiments	Performed the experiments	Investigation|Validation	YES
5526905	28798768	Q-FL	2	carried out mutant screening and validation experiments	carried out mutant screening and validation experiments	Performed the experiments	Investigation|Validation	YES
5526905	28798768	Y-CZ	2	designed and carried out the functional analysis and drafted the manuscript	designed and carried out the functional analysis and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5526905	28798768	Y-FZ	2	carried out histochemical assays	carried out histochemical assays	Performed the experiments	Investigation	YES
5526905	28798768	Y-QC	2	conceived of the study, and participated in its design and coordination and helped to draft the manuscript	conceived of the study, and participated in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
5526905	28798768	Y-ZF	2	carried out histochemical assays	carried out histochemical assays	Performed the experiments	Investigation	YES
5526905	28798768	YY	2	carried out mutant screening and validation experiments	carried out mutant screening and validation experiments	Performed the experiments	Investigation|Validation	YES
6155457	29250705	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6155457	29250705	B. There	2	are no individual persons data in this article	are no individual persons data in this article	-	-	NO
6155457	29250705	CAM	2	were involved in the original study design and conduct of the project	were involved in the original study design and conduct of the project	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6155457	29250705	LPH	2	were involved in the original study design and conduct of the project	were involved in the original study design and conduct of the project	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6155457	29250705	MB	2	were involved in the original study design and conduct of the project	were involved in the original study design and conduct of the project	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6155457	29250705	MKH	2	were involved in the original study design and conduct of the project	were involved in the original study design and conduct of the project	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6155457	29250705	MY	2	were involved in the original study design and conduct of the project|were co-supervisors	were involved in the original study design and conduct of the project	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6155457	29250705	MY	2	were involved in the original study design and conduct of the project|were co-supervisors	were co-supervisors	-	Supervision	YES
6155457	29250705	PhD	2	candidate who collected the data, analysed the data and prepared the first draft of the paper	candidate who collected the data, analysed the data and prepared the first draft of the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6155457	29250705	Ronald Philip Griffiths	2	the university of melbourne	the university of melbourne	-	-	NO
6155457	29250705	SMC	2	were involved in the original study design and conduct of the project	were involved in the original study design and conduct of the project	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6155457	29250705	Southern Health Human	2	ethics committee	ethics committee	-	-	NO
5594528	28893275	AF	2	wrote this review	wrote this review	Wrote the paper	Writing - Original Draft	YES
5594528	28893275	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5594528	28893275	JR	2	wrote this review	wrote this review	Wrote the paper	Writing - Original Draft	YES
5594528	28893275	SD	2	wrote this review	wrote this review	Wrote the paper	Writing - Original Draft	YES
6197735	30190207	All authors	2	contributed to and approved the final version of the manuscript	contributed to and approved the final version of the manuscript	-	-	NO
6197735	30190207	C.S.	2	performed mass spectrometry analysis|wrote the manuscript	performed mass spectrometry analysis	Performed the experiments	Investigation	YES
6197735	30190207	C.S.	2	performed mass spectrometry analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6197735	30190207	D.M.A.	2	performed mass spectrometry analysis	performed mass spectrometry analysis	Performed the experiments	Investigation	YES
6197735	30190207	F.H.B.	2	performed mass spectrometry analysis|wrote the manuscript	performed mass spectrometry analysis	Performed the experiments	Investigation	YES
6197735	30190207	F.H.B.	2	performed mass spectrometry analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6197735	30190207	G.M.	2	performed mass spectrometry analysis	performed mass spectrometry analysis	Performed the experiments	Investigation	YES
6197735	30190207	J.B.S.	2	supervised the study	supervised the study	-	Supervision	YES
6197735	30190207	K.B.	2	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
6197735	30190207	K.B.J.	2	conceived the idea|supervised the study|wrote the manuscript	conceived the idea	Conceived and designed the experiments	Conceptualization	YES
6197735	30190207	K.B.J.	2	conceived the idea|supervised the study|wrote the manuscript	supervised the study	-	Supervision	YES
6197735	30190207	K.B.J.	2	conceived the idea|supervised the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6197735	30190207	L.B.R.	2	assisted with immunohistochemistry	assisted with immunohistochemistry	Performed the experiments	Investigation	YES
6197735	30190207	O.H.N.	2	conceived the idea|designed the experiments|supervised the study|wrote the manuscript	conceived the idea	Conceived and designed the experiments	Conceptualization	YES
6197735	30190207	O.H.N.	2	conceived the idea|designed the experiments|supervised the study|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
6197735	30190207	O.H.N.	2	conceived the idea|designed the experiments|supervised the study|wrote the manuscript	supervised the study	-	Supervision	YES
6197735	30190207	O.H.N.	2	conceived the idea|designed the experiments|supervised the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6197735	30190207	Y.L.	2	conceived the idea|designed the experiments|wrote the manuscript	conceived the idea	Conceived and designed the experiments	Conceptualization	YES
6197735	30190207	Y.L.	2	conceived the idea|designed the experiments|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
6197735	30190207	Y.L.	2	conceived the idea|designed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5622352	28970452	David Wright	2	was involved in the development and oversight of the project and revision of the current manuscript	was involved in the development and oversight of the project and revision of the current manuscript	Wrote the paper	Supervision|Writing - Original Draft|Writing - Review & Editing	YES
5622352	28970452	Jane Sutton	2	was the lead researcher and involved in the development of the project|co-developed the survey, performed data collection, collation and analysis and was involved in the preparation of the original manuscript	was the lead researcher and involved in the development of the project	-	-	NO
5622352	28970452	Jane Sutton	2	was the lead researcher and involved in the development of the project|co-developed the survey, performed data collection, collation and analysis and was involved in the preparation of the original manuscript	co-developed the survey, performed data collection, collation and analysis and was involved in the preparation of the original manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5622352	28970452	Melanie Boughen	2	was project lead and involved in the development and oversight of the entire project|co-developed the survey and was involved in the analysis of the data and preparation and revision of the current manuscript	was project lead and involved in the development and oversight of the entire project	-	Supervision	YES
5622352	28970452	Melanie Boughen	2	was project lead and involved in the development and oversight of the entire project|co-developed the survey and was involved in the analysis of the data and preparation and revision of the current manuscript	co-developed the survey and was involved in the analysis of the data and preparation and revision of the current manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5622352	28970452	Tess Fenn	2	was gatekeeper to respondent access|co-developed the survey and was involved in the original manuscript	was gatekeeper to respondent access	-	-	NO
5622352	28970452	Tess Fenn	2	was gatekeeper to respondent access|co-developed the survey and was involved in the original manuscript	co-developed the survey and was involved in the original manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5090190	27822368	EPW	2	is the surgeon and main author who drafted the manuscript	is the surgeon and main author who drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5090190	27822368	FAE	2	is a gynaecologist who carried out some of the literature search	is a gynaecologist who carried out some of the literature search	Performed the experiments	Formal analysis|Investigation	YES
4405271	25897796	ADM	PLoS5	Revised the manuscript	Revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4405271	25897796	AE	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405271	25897796	AE	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405271	25897796	AE	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405271	25897796	FDC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405271	25897796	FDC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405271	25897796	FDC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405271	25897796	FDC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405271	25897796	FG	PLoS5	Checked the language revision|Revised the manuscript	Checked the language revision	Wrote the paper	Writing - Review & Editing	YES
4405271	25897796	FG	PLoS5	Checked the language revision|Revised the manuscript	Revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4405271	25897796	GA	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Checked the language revision	Performed the experiments	Performed the experiments	Investigation	YES
4405271	25897796	GA	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Checked the language revision	Analyzed the data	Analyzed the data	Formal analysis	YES
4405271	25897796	GA	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Checked the language revision	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405271	25897796	GA	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Checked the language revision	Checked the language revision	Wrote the paper	Writing - Review & Editing	YES
4405271	25897796	GP	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405271	25897796	GP	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405271	25897796	GP	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405271	25897796	SM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405271	25897796	SM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405271	25897796	SM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5526906	28798754	AF	2	wrote the first and second sections of the manuscript	wrote the first and second sections of the manuscript	Wrote the paper	Writing - Original Draft	YES
5526906	28798754	CB	2	wrote the second and third sections of the manuscript and conducted to the meta-analysis of data	wrote the second and third sections of the manuscript and conducted to the meta-analysis of data	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5526906	28798754	FF	2	carefully reviewed the manuscript	carefully reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5526906	28798754	FL	2	contributed to manuscript writing and carefully reviewed the manuscript	contributed to manuscript writing and carefully reviewed the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5526906	28798754	MC	2	carefully reviewed the manuscript	carefully reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5526906	28798754	MT	2	drafted the manuscript and wrote section three and four of the manuscript	drafted the manuscript and wrote section three and four of the manuscript	Wrote the paper	Writing - Original Draft	YES
4672403	26643455	MT	2	reviewed the manuscript and provided comments|worked on finalization of the manuscript	reviewed the manuscript and provided comments	Wrote the paper	Writing - Review & Editing	YES
4672403	26643455	MT	2	reviewed the manuscript and provided comments|worked on finalization of the manuscript	worked on finalization of the manuscript	Performed the experiments|Wrote the paper	Writing - Review & Editing	YES
4672403	26643455	NVB	2	co-drafted the manuscript|worked on finalization of the manuscript	co-drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4672403	26643455	NVB	2	co-drafted the manuscript|worked on finalization of the manuscript	worked on finalization of the manuscript	Performed the experiments|Wrote the paper	Writing - Review & Editing	YES
4672403	26643455	RK	2	co-drafted the manuscript|worked on finalization of the manuscript	co-drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4672403	26643455	RK	2	co-drafted the manuscript|worked on finalization of the manuscript	worked on finalization of the manuscript	Performed the experiments|Wrote the paper	Writing - Review & Editing	YES
6197783	30131305	A Fedorowski	2	were responsible for the interpretation of the data	were responsible for the interpretation of the data	Analyzed the data	Formal analysis	YES
6197783	30131305	O Haskard	2	were responsible for the interpretation of the data	were responsible for the interpretation of the data	Analyzed the data	Formal analysis	YES
6197783	30131305	O Melander	2	were responsible for the interpretation of the data	were responsible for the interpretation of the data	Analyzed the data	Formal analysis	YES
6197783	30131305	Y Khamis	2	critically revised by all other authors	critically revised by all other authors	Wrote the paper	Writing - Review & Editing	YES
6155478	29209876	AB	2	designed the study, conducted the literature search, performed mentalization assessment, made statistical analysis, and wrote the first draft of the paper	designed the study, conducted the literature search, performed mentalization assessment, made statistical analysis, and wrote the first draft of the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
6155478	29209876	All	2	datasets for this manuscript, in excel format, are available on request from the first author anna	datasets for this manuscript, in excel format, are available on request from the first author anna	-	-	NO
6155478	29209876	Both authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6155478	29209876	JKR	2	designed the study, recruited the patients, took part in the elaboration of results, and wrote the final version of the manuscript	designed the study, recruited the patients, took part in the elaboration of results, and wrote the final version of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
6155478	29209876	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5094680	27830064	Alexandros Rampotas	2	of the faculty	of the faculty	-	-	NO
5094680	27830064	Francois Sousa Dos	2	of the faculty	of the faculty	-	-	NO
5094680	27830064	GT	2	to the protocol	to the protocol	Conceived and designed the experiments	Methodology	YES
5094680	27830064	Georgios Paparoidamis	2	medical students who set up promotion and smooth run of the course, data collection and assistants to senior assessors	medical students who set up promotion and smooth run of the course, data collection and assistants to senior assessors	Performed the experiments	Investigation|Methodology	YES
5094680	27830064	International Lecturer	2	during course, edit of language of the manuscript	during course, edit of language of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5094680	27830064	International Lecturer During	2	senior advisor of the manual	senior advisor of the manual	-	-	NO
5094680	27830064	Ioannis Dimitropoulos	2	during course, edit of language of the manuscript	during course, edit of language of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5094680	27830064	Nikolaos Staikoglou	2	medical students who set up promotion and smooth run of the course, data collection and assistants to senior assessors	medical students who set up promotion and smooth run of the course, data collection and assistants to senior assessors	Performed the experiments	Investigation|Methodology	YES
5094680	27830064	Peter C. Whitfield	2	senior advisor of the manual	senior advisor of the manual	-	-	NO
5094680	27830064	Santos Members	2	of the faculty	of the faculty	-	-	NO
5622353	28970453	P.D.	PLoS52	conceived and designed the experiments|analyzed the data with the|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5622353	28970453	P.D.	PLoS52	conceived and designed the experiments|analyzed the data with the|wrote the paper	analyzed the data with the	Analyzed the data	Formal analysis	YES
5622353	28970453	P.D.	PLoS52	conceived and designed the experiments|analyzed the data with the|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5622353	28970453	Reading Statistical Services	PLoS52	helped with the analyzed the data with the	helped with the analyzed the data with the	Analyzed the data	Formal analysis	YES
5622353	28970453	W.M.L.	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data with the|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5622353	28970453	W.M.L.	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data with the|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5622353	28970453	W.M.L.	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data with the|wrote the paper	analyzed the data with the	Analyzed the data	Formal analysis	YES
5622353	28970453	W.M.L.	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data with the|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5594533	28893286	Both authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5594533	28893286	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
4672457	26643462	AA	2	developed the initial study design and protocol	developed the initial study design and protocol	Conceived and designed the experiments	Methodology	YES
4672457	26643462	CK	2	developed the initial study design and protocol|conducted the search, screening and data abstraction	developed the initial study design and protocol	Conceived and designed the experiments	Methodology	YES
4672457	26643462	CK	2	developed the initial study design and protocol|conducted the search, screening and data abstraction	conducted the search, screening and data abstraction	Performed the experiments	Investigation	YES
4672457	26643462	H. All	2	authors collaboratively discussed key decisions through the course of the review, provided critical feedback on preliminary drafts and interpretation of results and approved the final manuscript	authors collaboratively discussed key decisions through the course of the review, provided critical feedback on preliminary drafts and interpretation of results and approved the final manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
4672457	26643462	MN	2	developed the initial study design and protocol	developed the initial study design and protocol	Conceived and designed the experiments	Methodology	YES
4672457	26643462	RB	2	developed the initial study design and protocol	developed the initial study design and protocol	Conceived and designed the experiments	Methodology	YES
4672457	26643462	SH	2	conducted the search, screening and data abstraction	conducted the search, screening and data abstraction	Performed the experiments	Investigation	YES
4405272	25898011	FJW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405272	25898011	FJW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405272	25898011	FJW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405272	25898011	FJW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405272	25898011	FJW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405272	25898011	MVK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405272	25898011	MVK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405272	25898011	MVK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405272	25898011	NRL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405272	25898011	NRL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405272	25898011	NRL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405272	25898011	RCB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405272	25898011	RCB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405272	25898011	RCB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405272	25898011	RCB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405272	25898011	RCB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5526908	28798766	MS	2	has contributed to provide idea, information, and organization for writing, as well as writing some portion of the manuscript	has contributed to provide idea, information, and organization for writing, as well as writing some portion of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5526908	28798766	ST	2	has written the manuscript	has written the manuscript	Wrote the paper	Writing - Original Draft	YES
5096594	27833746	Ren Chongxi	2	has made substantial contributions to conception and design	has made substantial contributions to conception and design	Conceived and designed the experiments	Conceptualization	YES
5622354	28970454	Marketa Marvanova	7	conceived and co-designed the project; obtained irb study approval, performed and supervised the study; provided scientific input for data analysis; co-designed assessment tools; co-wrote the manuscript	conceived and co-designed the project; obtained irb study approval, performed and supervised the study; provided scientific input for data analysis; co-designed assessment tools; co-wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Project administration|Resources|Supervision|Writing - Original Draft	YES
5622354	28970454	Paul Henkel	7	conceived and co-designed the project; performed and supervised the study; performed the statistical analysis; co-designed assessment tools; co-wrote the manuscript	conceived and co-designed the project; performed and supervised the study; performed the statistical analysis; co-designed assessment tools; co-wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Supervision|Writing - Original Draft	YES
6161962	29858927	AK	2	localised the patients and visited the patients for the interviews, and wrote the first draft of the manuscript	localised the patients and visited the patients for the interviews, and wrote the first draft of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6161962	29858927	All authors	2	contributed to the study design, data interpretation and the writing of the manuscript|read and approved the final manuscript	contributed to the study design, data interpretation and the writing of the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Original Draft	YES
6161962	29858927	All authors	2	contributed to the study design, data interpretation and the writing of the manuscript|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5594534	28893282	Both authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5594534	28893282	JL	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5594534	28893282	MO	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5594534	28893282	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
4405273	25897780	BYW	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405273	25897780	BYW	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405273	25897780	CHC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405273	25897780	CHC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405273	25897780	CHC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405273	25897780	HX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405273	25897780	HX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405273	25897780	HX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405273	25897780	HX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405273	25897780	HX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405273	25897780	JSG	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405273	25897780	JSG	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405273	25897780	JSG	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405273	25897780	MHH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405273	25897780	MHH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405273	25897780	MHH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4672458	26643459	ACH	2	developed the manuscript structure and wrote the original draft	developed the manuscript structure and wrote the original draft	Wrote the paper	Writing - Original Draft	YES
4672458	26643459	AS	2	provided guidance and editorial support to the article	provided guidance and editorial support to the article	Wrote the paper	Supervision|Writing - Review & Editing	YES
4672458	26643459	ES	2	provided guidance and editorial support to the article	provided guidance and editorial support to the article	Wrote the paper	Supervision|Writing - Review & Editing	YES
4672458	26643459	MH	2	provided guidance and editorial support to the article	provided guidance and editorial support to the article	Wrote the paper	Supervision|Writing - Review & Editing	YES
4672458	26643459	RM	2	developed the manuscript structure and wrote the original draft	developed the manuscript structure and wrote the original draft	Wrote the paper	Writing - Original Draft	YES
4672458	26643459	SB	2	provided guidance and editorial support to the article	provided guidance and editorial support to the article	Wrote the paper	Supervision|Writing - Review & Editing	YES
4672458	26643459	SD	2	provided guidance and editorial support to the article	provided guidance and editorial support to the article	Wrote the paper	Supervision|Writing - Review & Editing	YES
4672458	26643459	SMB	2	developed the manuscript structure and wrote the original draft	developed the manuscript structure and wrote the original draft	Wrote the paper	Writing - Original Draft	YES
6284411	30341041	BCdJ	2	conceived the study|oversaw collection of isolates and ethical approval|wrote the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
6284411	30341041	BCdJ	2	conceived the study|oversaw collection of isolates and ethical approval|wrote the manuscript	oversaw collection of isolates and ethical approval	Performed the experiments	Investigation|Supervision	YES
6284411	30341041	BCdJ	2	conceived the study|oversaw collection of isolates and ethical approval|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6284411	30341041	CJM	2	conceived the study|undertook wgs assembly and data preparation|undertook all convergence and clustering analyses|undertook all phylodynamics|wrote the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
6284411	30341041	CJM	2	conceived the study|undertook wgs assembly and data preparation|undertook all convergence and clustering analyses|undertook all phylodynamics|wrote the manuscript	undertook wgs assembly and data preparation	Performed the experiments	Investigation	YES
6284411	30341041	CJM	2	conceived the study|undertook wgs assembly and data preparation|undertook all convergence and clustering analyses|undertook all phylodynamics|wrote the manuscript	undertook all convergence and clustering analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6284411	30341041	CJM	2	conceived the study|undertook wgs assembly and data preparation|undertook all convergence and clustering analyses|undertook all phylodynamics|wrote the manuscript	undertook all phylodynamics	Performed the experiments	Investigation	YES
6284411	30341041	CJM	2	conceived the study|undertook wgs assembly and data preparation|undertook all convergence and clustering analyses|undertook all phylodynamics|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6284411	30341041	CU	2	undertook wgs assembly and data preparation	undertook wgs assembly and data preparation	Performed the experiments	Investigation	YES
6284411	30341041	DK	2	undertook all phylodynamics	undertook all phylodynamics	Performed the experiments	Investigation	YES
6284411	30341041	FG	2	conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
6284411	30341041	JP	2	undertook all phylodynamics	undertook all phylodynamics	Performed the experiments	Investigation	YES
6284411	30341041	MKK	2	oversaw collection of isolates and ethical approval	oversaw collection of isolates and ethical approval	Performed the experiments	Investigation|Supervision	YES
6284411	30341041	MM	2	undertook classic genotyping and sequencing of isolates|undertook all phylodynamics	undertook classic genotyping and sequencing of isolates	Performed the experiments	Investigation	YES
6284411	30341041	MM	2	undertook classic genotyping and sequencing of isolates|undertook all phylodynamics	undertook all phylodynamics	Performed the experiments	Investigation	YES
6284411	30341041	PB	2	undertook classic genotyping and sequencing of isolates	undertook classic genotyping and sequencing of isolates	Performed the experiments	Investigation	YES
6284411	30341041	PL	2	undertook wgs assembly and data preparation	undertook wgs assembly and data preparation	Performed the experiments	Investigation	YES
6284411	30341041	PM	2	undertook wgs assembly and data preparation|undertook all phylodynamics|wrote the manuscript	undertook wgs assembly and data preparation	Performed the experiments	Investigation	YES
6284411	30341041	PM	2	undertook wgs assembly and data preparation|undertook all phylodynamics|wrote the manuscript	undertook all phylodynamics	Performed the experiments	Investigation	YES
6284411	30341041	PM	2	undertook wgs assembly and data preparation|undertook all phylodynamics|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6284411	30341041	SA	2	undertook classic genotyping and sequencing of isolates	undertook classic genotyping and sequencing of isolates	Performed the experiments	Investigation	YES
6284411	30341041	SN	2	undertook classic genotyping and sequencing of isolates|wrote the manuscript	undertook classic genotyping and sequencing of isolates	Performed the experiments	Investigation	YES
6284411	30341041	SN	2	undertook classic genotyping and sequencing of isolates|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6284411	30341041	TA	2	undertook wgs assembly and data preparation	undertook wgs assembly and data preparation	Performed the experiments	Investigation	YES
6284411	30341041	TAK	2	undertook classic genotyping and sequencing of isolates	undertook classic genotyping and sequencing of isolates	Performed the experiments	Investigation	YES
6284411	30341041	TS	2	undertook all phylodynamics	undertook all phylodynamics	Performed the experiments	Investigation	YES
5109254	27872746	Andrew Goertzen	7	Data analysis, writing. Richard	Data analysis, writing. Richard	Analyzed the data|Wrote the paper	Formal analysis	YES
5109254	27872746	D Leslie	7	Study design, data collections, data analysis, writing	Study design, data collections, data analysis, writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology	YES
5109254	27872746	Kumar A. Pathak	7	Study design, data collections, data analysis, writing	Study design, data collections, data analysis, writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology	YES
5109254	27872746	Thomas Klonisch	7	Study design, writing. William	Study design, writing. William	Conceived and designed the experiments|Wrote the paper	Methodology	YES
5109254	27872746	W Nason	7	Study design, writing	Study design, writing	Conceived and designed the experiments|Wrote the paper	Methodology	YES
5622355	28970455	All authors	2	had substantial contribution and completed manuscript in a significant matter	had substantial contribution and completed manuscript in a significant matter	-	-	NO
5622355	28970455	Damian Swieczkowski	2	prepared and revised the manuscript	prepared and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5622355	28970455	Milosz Jaguszewski	2	supervised the project	supervised the project	-	Supervision	YES
5622355	28970455	Piotr Merks	2	supervised the project	supervised the project	-	Supervision	YES
6161963	29352395	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6161963	29352395	BE	2	coordinated patients inclusion	coordinated patients inclusion	-	Project administration	YES
6161963	29352395	CH	2	coordinated patients inclusion	coordinated patients inclusion	-	Project administration	YES
6161963	29352395	CM	2	participated to the experimental work and to the statistical analyses|participated to the experimental work and to the statistical analyses	participated to the experimental work and to the statistical analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6161963	29352395	CM	2	participated to the experimental work and to the statistical analyses|participated to the experimental work and to the statistical analyses	participated to the experimental work and to the statistical analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6161963	29352395	DB	2	participated to the experimental work and to the statistical analyses	participated to the experimental work and to the statistical analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6161963	29352395	DC	2	coordinated the study and wrote the manuscript	coordinated the study and wrote the manuscript	Wrote the paper	Project administration|Writing - Original Draft	YES
6161963	29352395	FB	2	coordinated patients inclusion	coordinated patients inclusion	-	Project administration	YES
6161963	29352395	JO	2	coordinated the study and wrote the manuscript|finalized the manuscript	coordinated the study and wrote the manuscript	Wrote the paper	Project administration|Writing - Original Draft	YES
6161963	29352395	JO	2	coordinated the study and wrote the manuscript|finalized the manuscript	finalized the manuscript	Wrote the paper	Writing - Review & Editing	YES
6161963	29352395	JPK	2	coordinated patients inclusion	coordinated patients inclusion	-	Project administration	YES
6161963	29352395	MB	2	participated to the experimental work and to the statistical analyses	participated to the experimental work and to the statistical analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6161963	29352395	ML	2	coordinated the study and wrote the manuscript|finalized the manuscript	coordinated the study and wrote the manuscript	Wrote the paper	Project administration|Writing - Original Draft	YES
6161963	29352395	ML	2	coordinated the study and wrote the manuscript|finalized the manuscript	finalized the manuscript	Wrote the paper	Writing - Review & Editing	YES
6161963	29352395	NH	2	coordinated patients inclusion	coordinated patients inclusion	-	Project administration	YES
6161963	29352395	RK	2	coordinated the study and wrote the manuscript	coordinated the study and wrote the manuscript	Wrote the paper	Project administration|Writing - Original Draft	YES
6161963	29352395	RT	2	coordinated the study and wrote the manuscript|finalized the manuscript	coordinated the study and wrote the manuscript	Wrote the paper	Project administration|Writing - Original Draft	YES
6161963	29352395	RT	2	coordinated the study and wrote the manuscript|finalized the manuscript	finalized the manuscript	Wrote the paper	Writing - Review & Editing	YES
6161963	29352395	WB	2	coordinated the study and wrote the manuscript|finalized the manuscript	coordinated the study and wrote the manuscript	Wrote the paper	Project administration|Writing - Original Draft	YES
6161963	29352395	WB	2	coordinated the study and wrote the manuscript|finalized the manuscript	finalized the manuscript	Wrote the paper	Writing - Review & Editing	YES
5260014	28155661	DW	PLoS52	wrote the paper|was the principle investigator and conceived the analyses	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5260014	28155661	DW	PLoS52	wrote the paper|was the principle investigator and conceived the analyses	was the principle investigator and conceived the analyses	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
5260014	28155661	FCHW	PLoS52	designed the analyses|collected the data|performed the analyses|wrote the paper	designed the analyses	Conceived and designed the experiments|Analyzed the data	Formal analysis	YES
5260014	28155661	FCHW	PLoS52	designed the analyses|collected the data|performed the analyses|wrote the paper	collected the data	Performed the experiments	Investigation	YES
5260014	28155661	FCHW	PLoS52	designed the analyses|collected the data|performed the analyses|wrote the paper	performed the analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5260014	28155661	FCHW	PLoS52	designed the analyses|collected the data|performed the analyses|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5260014	28155661	YJY	PLoS52	collected the data	collected the data	Performed the experiments	Investigation	YES
5526916	28798757	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5526916	28798757	MCVP	2	designed and coordinated the study and participated in the drafting and revising of the manuscript	designed and coordinated the study and participated in the drafting and revising of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft|Writing - Review & Editing	YES
5526916	28798757	MD	2	performed the dna isolation and the ssr genotyping	performed the dna isolation and the ssr genotyping	Performed the experiments	Investigation	YES
5526916	28798757	MMV	2	coordinated the field experiment and performed the plant agronomic traits evaluations	coordinated the field experiment and performed the plant agronomic traits evaluations	Performed the experiments	Investigation|Project administration	YES
5526916	28798757	STL	2	performed the dna isolation and the ssr genotyping|participated in the seed morphological characterization, data analysis, and drafted the manuscript	performed the dna isolation and the ssr genotyping	Performed the experiments	Investigation	YES
5526916	28798757	STL	2	performed the dna isolation and the ssr genotyping|participated in the seed morphological characterization, data analysis, and drafted the manuscript	participated in the seed morphological characterization, data analysis, and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5526916	28798757	ZS	2	performed the statistical analysis of the molecular and phenotypic data and revised the manuscript critically	performed the statistical analysis of the molecular and phenotypic data and revised the manuscript critically	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
4405274	25898146	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405274	25898146	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405274	25898146	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405274	25898146	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405274	25898146	LIE	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4405274	25898146	LIE	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4405274	25898146	MEV	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405274	25898146	MEV	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405274	25898146	MEV	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405274	25898146	MJM	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405274	25898146	MJM	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5594582	28893294	Both authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5594582	28893294	GAD	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5594582	28893294	JDD	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5109256	27872745	All authors	2	have contributed as a group to all aspects of publications	have contributed as a group to all aspects of publications	-	-	NO
4672459	26643458	AW	2	conceived the study|edited the draft	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4672459	26643458	AW	2	conceived the study|edited the draft	edited the draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4672459	26643458	All authors	2	designed the study, and collected and interpreted the data	designed the study, and collected and interpreted the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
4672459	26643458	CC	2	edited the draft	edited the draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4672459	26643458	ETC	2	conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4672459	26643458	HN	2	edited the draft	edited the draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4672459	26643458	LO	2	conceived the study|edited the draft	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4672459	26643458	LO	2	conceived the study|edited the draft	edited the draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4672459	26643458	MJV	2	conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4672459	26643458	SB	2	conceived the study|edited the draft	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4672459	26643458	SB	2	conceived the study|edited the draft	edited the draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5121134	27895905	Both authors	2	were involved from the outset with study design, and data collection	were involved from the outset with study design, and data collection	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6284414	30341038	DL	PLoS52	participated in the planning and design of the study|participate the results interpretation	participated in the planning and design of the study	Conceived and designed the experiments	Methodology	YES
6284414	30341038	DL	PLoS52	participated in the planning and design of the study|participate the results interpretation	participate the results interpretation	Analyzed the data	Formal analysis	YES
6284414	30341038	DZ	PLoS52	design the protocol of data scanning and collection|contributed to the recruitment of subjects in the beijing site	design the protocol of data scanning and collection	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6284414	30341038	DZ	PLoS52	design the protocol of data scanning and collection|contributed to the recruitment of subjects in the beijing site	contributed to the recruitment of subjects in the beijing site	Performed the experiments	Investigation	YES
6284414	30341038	FZ	PLoS52	participate the results interpretation	participate the results interpretation	Analyzed the data	Formal analysis	YES
6284414	30341038	HY	PLoS52	contributed to the recruitment of subjects in the beijing site	contributed to the recruitment of subjects in the beijing site	Performed the experiments	Investigation	YES
6284414	30341038	JC	PLoS52	participated in the planning and design of the study|wrote the paper|participate the results interpretation	participated in the planning and design of the study	Conceived and designed the experiments	Methodology	YES
6284414	30341038	JC	PLoS52	participated in the planning and design of the study|wrote the paper|participate the results interpretation	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6284414	30341038	JC	PLoS52	participated in the planning and design of the study|wrote the paper|participate the results interpretation	participate the results interpretation	Analyzed the data	Formal analysis	YES
6284414	30341038	JL	PLoS52	preprocessed the data|participate the results interpretation	preprocessed the data	Analyzed the data	Data curation	YES
6284414	30341038	JL	PLoS52	preprocessed the data|participate the results interpretation	participate the results interpretation	Analyzed the data	Formal analysis	YES
6284414	30341038	JS	PLoS52	participated in the planning and design of the study|wrote the paper|participate the results interpretation	participated in the planning and design of the study	Conceived and designed the experiments	Methodology	YES
6284414	30341038	JS	PLoS52	participated in the planning and design of the study|wrote the paper|participate the results interpretation	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6284414	30341038	JS	PLoS52	participated in the planning and design of the study|wrote the paper|participate the results interpretation	participate the results interpretation	Analyzed the data	Formal analysis	YES
6284414	30341038	JY	PLoS52	contributed to the recruitment of subjects in the beijing site	contributed to the recruitment of subjects in the beijing site	Performed the experiments	Investigation	YES
6284414	30341038	KX	PLoS52	preprocessed the data	preprocessed the data	Analyzed the data	Data curation	YES
6284414	30341038	LF	PLoS52	participate the results interpretation	participate the results interpretation	Analyzed the data	Formal analysis	YES
6284414	30341038	LL	PLoS52	contributed to the recruitment of subjects in the beijing site	contributed to the recruitment of subjects in the beijing site	Performed the experiments	Investigation	YES
6284414	30341038	MS	PLoS52	design the protocol of data scanning and collection	design the protocol of data scanning and collection	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6284414	30341038	NL	PLoS52	participated in the planning and design of the study|conducted the data analysis|wrote the paper|preprocessed the data	participated in the planning and design of the study	Conceived and designed the experiments	Methodology	YES
6284414	30341038	NL	PLoS52	participated in the planning and design of the study|conducted the data analysis|wrote the paper|preprocessed the data	conducted the data analysis	Analyzed the data	Formal analysis	YES
6284414	30341038	NL	PLoS52	participated in the planning and design of the study|conducted the data analysis|wrote the paper|preprocessed the data	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6284414	30341038	NL	PLoS52	participated in the planning and design of the study|conducted the data analysis|wrote the paper|preprocessed the data	preprocessed the data	Analyzed the data	Data curation	YES
6284414	30341038	NZ	PLoS52	participate the results interpretation	participate the results interpretation	Analyzed the data	Formal analysis	YES
6284414	30341038	PL	PLoS52	contributed to the recruitment of subjects in the beijing site	contributed to the recruitment of subjects in the beijing site	Performed the experiments	Investigation	YES
6284414	30341038	SL	PLoS52	preprocessed the data	preprocessed the data	Analyzed the data	Data curation	YES
6284414	30341038	TJ	PLoS52	participated in the planning and design of the study|design the protocol of data scanning and collection	participated in the planning and design of the study	Conceived and designed the experiments	Methodology	YES
6284414	30341038	TJ	PLoS52	participated in the planning and design of the study|design the protocol of data scanning and collection	design the protocol of data scanning and collection	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6284414	30341038	VDC	PLoS52	participate the results interpretation	participate the results interpretation	Analyzed the data	Formal analysis	YES
6284414	30341038	VMV	PLoS52	participate the results interpretation	participate the results interpretation	Analyzed the data	Formal analysis	YES
6284414	30341038	YC	PLoS52	participate the results interpretation	participate the results interpretation	Analyzed the data	Formal analysis	YES
6284414	30341038	ZY	PLoS52	participate the results interpretation	participate the results interpretation	Analyzed the data	Formal analysis	YES
5260015	28155662	DS	2	designed the methods and experimental setup|wrote the manuscript	designed the methods and experimental setup	Conceived and designed the experiments|Performed the experiments	Methodology	YES
5260015	28155662	DS	2	designed the methods and experimental setup|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5260015	28155662	HP	2	designed the methods and experimental setup|carried out the implementation of the various methods	designed the methods and experimental setup	Conceived and designed the experiments|Performed the experiments	Methodology	YES
5260015	28155662	HP	2	designed the methods and experimental setup|carried out the implementation of the various methods	carried out the implementation of the various methods	Performed the experiments	Investigation	YES
5260015	28155662	SD	2	designed the methods and experimental setup|carried out the implementation of the various methods|developed the webserver|wrote the manuscript	designed the methods and experimental setup	Conceived and designed the experiments|Performed the experiments	Methodology	YES
5260015	28155662	SD	2	designed the methods and experimental setup|carried out the implementation of the various methods|developed the webserver|wrote the manuscript	carried out the implementation of the various methods	Performed the experiments	Investigation	YES
5260015	28155662	SD	2	designed the methods and experimental setup|carried out the implementation of the various methods|developed the webserver|wrote the manuscript	developed the webserver	Contributed reagents/materials/analysis tools	Software	YES
5260015	28155662	SD	2	designed the methods and experimental setup|carried out the implementation of the various methods|developed the webserver|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5260015	28155662	SM	2	designed the methods and experimental setup|carried out the implementation of the various methods|developed the webserver|wrote the manuscript	designed the methods and experimental setup	Conceived and designed the experiments|Performed the experiments	Methodology	YES
5260015	28155662	SM	2	designed the methods and experimental setup|carried out the implementation of the various methods|developed the webserver|wrote the manuscript	carried out the implementation of the various methods	Performed the experiments	Investigation	YES
5260015	28155662	SM	2	designed the methods and experimental setup|carried out the implementation of the various methods|developed the webserver|wrote the manuscript	developed the webserver	Contributed reagents/materials/analysis tools	Software	YES
5260015	28155662	SM	2	designed the methods and experimental setup|carried out the implementation of the various methods|developed the webserver|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6161964	29457195	AA	2	conducted the statistical analysis and participated in manuscript preparation	conducted the statistical analysis and participated in manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6161964	29457195	AD	2	conducted the statistical analysis and participated in manuscript preparation	conducted the statistical analysis and participated in manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6161964	29457195	AF	2	conducted subject assessments and data collection and assisted with analysis of actigraphy data	conducted subject assessments and data collection and assisted with analysis of actigraphy data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6161964	29457195	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6161964	29457195	CM	2	contributed to the study design and contributed to the preparation of the manuscript	contributed to the study design and contributed to the preparation of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
6161964	29457195	CT	2	assisted in the protocol implementation and sample recruitment	assisted in the protocol implementation and sample recruitment	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6161964	29457195	Center El Paso	2	institutional review boards and was consistent with standard for the ethical conduct of human research	institutional review boards and was consistent with standard for the ethical conduct of human research	Performed the experiments	Investigation	YES
6161964	29457195	JZ	2	contributed to the analysis of the data interpretation to the preparation of the manuscript	contributed to the analysis of the data interpretation to the preparation of the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
6161964	29457195	MT	2	assisted in the protocol implementation and sample recruitment	assisted in the protocol implementation and sample recruitment	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6161964	29457195	RG	2	is the principal investigator of this research protocol|was involved in the project design, statistical analysis, sample recruitment and assessment	is the principal investigator of this research protocol	Conceived and designed the experiments	Conceptualization|Funding acquisition|Methodology	YES
6161964	29457195	RG	2	is the principal investigator of this research protocol|was involved in the project design, statistical analysis, sample recruitment and assessment	was involved in the project design, statistical analysis, sample recruitment and assessment	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
6161964	29457195	TS	2	contributed to the study design and contributed to the preparation of the manuscript	contributed to the study design and contributed to the preparation of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
6161964	29457195	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
4477184	26180802	Alison Malkin	2	revised and approved the paper for submission	revised and approved the paper for submission	Wrote the paper	Writing - Review & Editing	YES
4477184	26180802	Fiona Mary Lyng	2	revised and approved the paper for submission	revised and approved the paper for submission	Wrote the paper	Writing - Review & Editing	YES
4405275	25897756	BHC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405275	25897756	BHC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405275	25897756	BHC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405275	25897756	BSC	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4405275	25897756	CWP	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4405275	25897756	CWY	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405275	25897756	CWY	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405275	25897756	CWY	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405275	25897756	EJO	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405275	25897756	HDK	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4405275	25897756	ISM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405275	25897756	JIK	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405275	25897756	JSL	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4405275	25897756	YSK	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405275	25897756	YYJ	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5526918	28798762	GH	2	supplied helps in revising the manuscript	supplied helps in revising the manuscript	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Review & Editing	YES
5526918	28798762	LY	2	performed research and wrote the manuscript	performed research and wrote the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5526918	28798762	NL	2	supplied helps in some experiments	supplied helps in some experiments	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5526918	28798762	SH	2	supplied helps in revising the manuscript	supplied helps in revising the manuscript	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Review & Editing	YES
5526918	28798762	WH	2	supplied helps in some experiments	supplied helps in some experiments	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5526918	28798762	ZL	2	directed research	directed research	-	Supervision	YES
5622357	28970457	Benjamin S. Teeter	2	contributed to study planning, data collection, and manuscript editing	contributed to study planning, data collection, and manuscript editing	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Methodology|Resources|Writing - Review & Editing	YES
5622357	28970457	Lindsey A. Hohmann	2	contributed to data analysis and manuscript preparation	contributed to data analysis and manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5622357	28970457	Salisa C. Westrick	2	contributed to all aspects of the study, leading the study design and data collection as well as serving as the corresponding author	contributed to all aspects of the study, leading the study design and data collection as well as serving as the corresponding author	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources	YES
5622357	28970457	Stuart J. Farland	2	contributed to study planning, data collection, and manuscript editing	contributed to study planning, data collection, and manuscript editing	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Methodology|Resources|Writing - Review & Editing	YES
5622357	28970457	Tessa J. Hastings	2	contributed to data analysis and lead the manuscript preparation	contributed to data analysis and lead the manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5594601	28893290	Both authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5594601	28893290	MG	2	wrote and edited this manuscript	wrote and edited this manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5594601	28893290	ML	2	wrote and edited this manuscript	wrote and edited this manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5594601	28893290	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
4676422	26653859	CEN	2	is solely responsible for the authorship of this viewpoint	is solely responsible for the authorship of this viewpoint	-	-	NO
5121137	27895906	Barbara Saenz Ibarra	7	simple analysis. Blanca I	simple analysis. Blanca I	-	-	NO
5121137	27895906	Cavazos Cavazos	7	sampling	sampling	Performed the experiments	Investigation	YES
5121137	27895906	Esquivel Gacia	7	medical records management	medical records management	-	-	NO
5121137	27895906	Jose Luis Trevino	7	proyect planning, manuscript development, and analysis	proyect planning, manuscript development, and analysis	Conceived and designed the experiments	Methodology	YES
5121137	27895906	MD	7	medical procedure application|proyect supervision. Marco A|sample analysis. Lucia M|sampling|simple analysis. Blanca I|medical records management|proyect planning, manuscript development, and analysis	medical procedure application	Performed the experiments	Investigation	YES
5121137	27895906	MD	7	medical procedure application|proyect supervision. Marco A|sample analysis. Lucia M|sampling|simple analysis. Blanca I|medical records management|proyect planning, manuscript development, and analysis	proyect supervision. Marco A	-	Supervision	YES
5121137	27895906	MD	7	medical procedure application|proyect supervision. Marco A|sample analysis. Lucia M|sampling|simple analysis. Blanca I|medical records management|proyect planning, manuscript development, and analysis	sample analysis. Lucia M	Analyzed the data	Formal analysis	YES
5121137	27895906	MD	7	medical procedure application|proyect supervision. Marco A|sample analysis. Lucia M|sampling|simple analysis. Blanca I|medical records management|proyect planning, manuscript development, and analysis	sampling	Performed the experiments	Investigation	YES
5121137	27895906	MD	7	medical procedure application|proyect supervision. Marco A|sample analysis. Lucia M|sampling|simple analysis. Blanca I|medical records management|proyect planning, manuscript development, and analysis	simple analysis. Blanca I	-	-	NO
5121137	27895906	MD	7	medical procedure application|proyect supervision. Marco A|sample analysis. Lucia M|sampling|simple analysis. Blanca I|medical records management|proyect planning, manuscript development, and analysis	medical records management	-	-	NO
5121137	27895906	MD	7	medical procedure application|proyect supervision. Marco A|sample analysis. Lucia M|sampling|simple analysis. Blanca I|medical records management|proyect planning, manuscript development, and analysis	proyect planning, manuscript development, and analysis	Conceived and designed the experiments	Methodology	YES
5121137	27895906	Marco Antonio Mendez	7	medical procedure application	medical procedure application	Performed the experiments	Investigation	YES
5121137	27895906	Mario de Jesus Villegas Gonzalez	7	proyect supervision. Marco A	proyect supervision. Marco A	-	Supervision	YES
5121137	27895906	PhD	7	proyect supervision. Marco A|sample analysis. Lucia M|proyect planning, manuscript development, and analysis	proyect supervision. Marco A	-	Supervision	YES
5121137	27895906	PhD	7	proyect supervision. Marco A|sample analysis. Lucia M|proyect planning, manuscript development, and analysis	sample analysis. Lucia M	Analyzed the data	Formal analysis	YES
5121137	27895906	PhD	7	proyect supervision. Marco A|sample analysis. Lucia M|proyect planning, manuscript development, and analysis	proyect planning, manuscript development, and analysis	Conceived and designed the experiments	Methodology	YES
5121137	27895906	Ponce Camacho	7	sample analysis. Lucia M	sample analysis. Lucia M	Analyzed the data	Formal analysis	YES
4405276	25897957	AY	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405276	25897957	AY	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405276	25897957	IM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405276	25897957	IM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405276	25897957	IM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405276	25897957	IM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405276	25897957	IM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405276	25897957	JKN	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405276	25897957	JKN	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405276	25897957	JKN	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405276	25897957	PH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405276	25897957	PH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405276	25897957	PH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405276	25897957	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405276	25897957	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405276	25897957	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405276	25897957	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405276	25897957	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6286188	30389506	AC	1	Data preparation	Data preparation	-	-	NO
6286188	30389506	ADM	1	Data collection	Data collection	Performed the experiments	Investigation	YES
6286188	30389506	AMM	1	Data collection	Data collection	Performed the experiments	Investigation	YES
6286188	30389506	DJP	1	Conception and design|Data collection	Conception and design	Conceived and designed the experiments	Conceptualization	YES
6286188	30389506	DJP	1	Conception and design|Data collection	Data collection	Performed the experiments	Investigation	YES
6286188	30389506	DLM	1	Conception and design|Data analysis|Drafting the article|Data preparation	Conception and design	Conceived and designed the experiments	Conceptualization	YES
6286188	30389506	DLM	1	Conception and design|Data analysis|Drafting the article|Data preparation	Data analysis	Analyzed the data	Formal analysis	YES
6286188	30389506	DLM	1	Conception and design|Data analysis|Drafting the article|Data preparation	Drafting the article	Wrote the paper	Writing - Original Draft	YES
6286188	30389506	DLM	1	Conception and design|Data analysis|Drafting the article|Data preparation	Data preparation	-	-	NO
6286188	30389506	IJD	1	Conception and design	Conception and design	Conceived and designed the experiments	Conceptualization	YES
6286188	30389506	KLE	1	Data collection	Data collection	Performed the experiments	Investigation	YES
6286188	30389506	MLB	1	Data preparation	Data preparation	-	-	NO
6286188	30389506	PMV	1	Conception and design	Conception and design	Conceived and designed the experiments	Conceptualization	YES
6286188	30389506	REM	1	Conception and design|Drafting the article|Data preparation	Conception and design	Conceived and designed the experiments	Conceptualization	YES
6286188	30389506	REM	1	Conception and design|Drafting the article|Data preparation	Drafting the article	Wrote the paper	Writing - Original Draft	YES
6286188	30389506	REM	1	Conception and design|Drafting the article|Data preparation	Data preparation	-	-	NO
6286188	30389506	RMW	1	Data preparation	Data preparation	-	-	NO
6286188	30389506	SWM	1	Data preparation	Data preparation	-	-	NO
6286188	30389506	all authors	1	Revision of the article	Revision of the article	Wrote the paper	Writing - Review & Editing	YES
5260030	28155670	CA	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5260030	28155670	ESAP	2	as end-users	as end-users	-	-	NO
5260030	28155670	JP	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5260030	28155670	NT	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5260030	28155670	PP	2	wrote the perl scripts, conducted all experiments and drafted the manuscript	wrote the perl scripts, conducted all experiments and drafted the manuscript	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Software|Writing - Original Draft	YES
5260030	28155670	PS	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5260030	28155670	ST	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5594608	28893278	All authors	2	contributed to writing and reviewing the manuscript|read and approved the final manuscript	contributed to writing and reviewing the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5594608	28893278	All authors	2	contributed to writing and reviewing the manuscript|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5594608	28893278	NIAID	2	authors declare that they have no competing interests	authors declare that they have no competing interests	-	-	NO
5594608	28893278	NIH	2	authors declare that they have no competing interests	authors declare that they have no competing interests	-	-	NO
5622358	28970458	Hassan Raza	2	are responsible for initiating and designing the study, data interpretation, and manuscript writing|played a part in design and development of the questionnaire, and conducting the study	are responsible for initiating and designing the study, data interpretation, and manuscript writing	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5622358	28970458	Hassan Raza	2	are responsible for initiating and designing the study, data interpretation, and manuscript writing|played a part in design and development of the questionnaire, and conducting the study	played a part in design and development of the questionnaire, and conducting the study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5622358	28970458	Kiran Ajmal	2	contributed to developing the questionnaire and providing necessary information regarding the curriculum|also reviewed the manuscript	contributed to developing the questionnaire and providing necessary information regarding the curriculum	-	-	NO
5622358	28970458	Kiran Ajmal	2	contributed to developing the questionnaire and providing necessary information regarding the curriculum|also reviewed the manuscript	also reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5622358	28970458	Saima Mahmood Malhi	2	are responsible for initiating and designing the study, data interpretation, and manuscript writing|is further responsible for the analysis of data, discussion questionnaire development and overall review of the manuscript	are responsible for initiating and designing the study, data interpretation, and manuscript writing	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5622358	28970458	Saima Mahmood Malhi	2	are responsible for initiating and designing the study, data interpretation, and manuscript writing|is further responsible for the analysis of data, discussion questionnaire development and overall review of the manuscript	is further responsible for the analysis of data, discussion questionnaire development and overall review of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5622358	28970458	Sumbul Shamim	2	provided the permission to conduct the study and took care of legal aspects	provided the permission to conduct the study and took care of legal aspects	Performed the experiments	Investigation	YES
5622358	28970458	Syed Muhammad Sharib	2	played a part in design and development of the questionnaire, and conducting the study	played a part in design and development of the questionnaire, and conducting the study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6161965	29992455	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6161965	29992455	DG	2	wrote the manuscript|provided data and statistical analysis	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6161965	29992455	DG	2	wrote the manuscript|provided data and statistical analysis	provided data and statistical analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6161965	29992455	DM	2	were involved in the design and data acquisition of the study|wrote the manuscript|oversaw the research and provided additional interpretation of data	were involved in the design and data acquisition of the study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6161965	29992455	DM	2	were involved in the design and data acquisition of the study|wrote the manuscript|oversaw the research and provided additional interpretation of data	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6161965	29992455	DM	2	were involved in the design and data acquisition of the study|wrote the manuscript|oversaw the research and provided additional interpretation of data	oversaw the research and provided additional interpretation of data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources|Supervision	YES
6161965	29992455	KA	2	provided data and statistical analysis	provided data and statistical analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6161965	29992455	LW	2	were involved in the design and data acquisition of the study|oversaw the research and provided additional interpretation of data	were involved in the design and data acquisition of the study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6161965	29992455	LW	2	were involved in the design and data acquisition of the study|oversaw the research and provided additional interpretation of data	oversaw the research and provided additional interpretation of data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources|Supervision	YES
6161965	29992455	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5526919	28798761	HO	2	assisted and edited the manuscript	assisted and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5526919	28798761	JK	2	assisted and edited the manuscript|contributed in critically revising the draft and updating the manuscript for publication	assisted and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5526919	28798761	JK	2	assisted and edited the manuscript|contributed in critically revising the draft and updating the manuscript for publication	contributed in critically revising the draft and updating the manuscript for publication	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5526919	28798761	PS	2	assisted and edited the manuscript|contributed in critically revising the draft and updating the manuscript for publication	assisted and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5526919	28798761	PS	2	assisted and edited the manuscript|contributed in critically revising the draft and updating the manuscript for publication	contributed in critically revising the draft and updating the manuscript for publication	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5526919	28798761	RS	2	contributed in critically revising the draft and updating the manuscript for publication	contributed in critically revising the draft and updating the manuscript for publication	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5526919	28798761	RY	2	conceptualized the manuscript|assisted and edited the manuscript	conceptualized the manuscript	Conceived and designed the experiments	Conceptualization	YES
5526919	28798761	RY	2	conceptualized the manuscript|assisted and edited the manuscript	assisted and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5526919	28798761	SP	2	conceptualized the manuscript|wrote the manuscript|contributed in critically revising the draft and updating the manuscript for publication	conceptualized the manuscript	Conceived and designed the experiments	Conceptualization	YES
5526919	28798761	SP	2	conceptualized the manuscript|wrote the manuscript|contributed in critically revising the draft and updating the manuscript for publication	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5526919	28798761	SP	2	conceptualized the manuscript|wrote the manuscript|contributed in critically revising the draft and updating the manuscript for publication	contributed in critically revising the draft and updating the manuscript for publication	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5121141	27895909	Abu Minhajuddin	5	contributed to: - the study design and analysis and interpretation of data	contributed to: - the study design and analysis and interpretation of data	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Methodology|Resources	YES
5121141	27895909	Ahmad Elsharydah	5	contributed to: - the study concept and design	contributed to: - the study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5121141	27895909	Kimberly Warmack	5	contributed to: - analysis and interpretation of data	contributed to: - analysis and interpretation of data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5121141	27895909	Susan D. Moffatt-Bruce	5	contributed to: - analysis and interpretation of data	contributed to: - analysis and interpretation of data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
4676808	26654029	All authors	2	provided input to the writing of the manuscript and approved the final version	provided input to the writing of the manuscript and approved the final version	Wrote the paper	Writing - Original Draft	YES
4676808	26654029	DMM	2	designed the data analysis	designed the data analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis	YES
4676808	26654029	JB	2	provided input to the early drafts	provided input to the early drafts	Wrote the paper	Writing - Original Draft	YES
4676808	26654029	JK	2	designed the data analysis	designed the data analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis	YES
4676808	26654029	LL	2	designed the data analysis	designed the data analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis	YES
4676808	26654029	MNa	2	designed the data analysis|supervised the data collection	designed the data analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis	YES
4676808	26654029	MNa	2	designed the data analysis|supervised the data collection	supervised the data collection	Performed the experiments	Investigation|Supervision	YES
4676808	26654029	MNy	2	supervised the data collection	supervised the data collection	Performed the experiments	Investigation|Supervision	YES
4676808	26654029	PK	2	supervised the viral load testing|provided input to the early drafts	supervised the viral load testing	Performed the experiments	Investigation|Supervision	YES
4676808	26654029	PK	2	supervised the viral load testing|provided input to the early drafts	provided input to the early drafts	Wrote the paper	Writing - Original Draft	YES
4676808	26654029	PM	2	provided input to the early drafts	provided input to the early drafts	Wrote the paper	Writing - Original Draft	YES
4676808	26654029	RTL	2	provided input to the early drafts	provided input to the early drafts	Wrote the paper	Writing - Original Draft	YES
4676808	26654029	SO	2	provided input to the early drafts	provided input to the early drafts	Wrote the paper	Writing - Original Draft	YES
4676808	26654029	WZ	2	conducted the analysis	conducted the analysis	Performed the experiments	Investigation	YES
5121144	27895907	HCM	CRediT	Critical language and grammar revision	Critical language and grammar revision	Wrote the paper	Writing - Review & Editing	YES
5121144	27895907	HMC	CRediT	supervision	supervision	-	Supervision	YES
5121144	27895907	HRH	CRediT	supervision	supervision	-	Supervision	YES
5121144	27895907	TCW	CRediT	Critical language and grammar revision	Critical language and grammar revision	Wrote the paper	Writing - Review & Editing	YES
5121144	27895907	WYM	CRediT	supervision	supervision	-	Supervision	YES
5260053	28155664	KN	2	supervised the conducted all the research and wrote the paper under the	supervised the conducted all the research and wrote the paper under the	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Original Draft	YES
5260053	28155664	MM	2	conducted all the research and wrote the paper under the	conducted all the research and wrote the paper under the	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6354709	30552062	All authors	2	discussed the results and commented on the manuscript	discussed the results and commented on the manuscript	-	-	NO
6354709	30552062	H.B.A.	2	assisted in the experiment design and performance, discussed and analyzed data and gave conceptual advice	assisted in the experiment design and performance, discussed and analyzed data and gave conceptual advice	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation|Methodology	YES
6354709	30552062	I.L.	2	performed in vitro and in vivo experiments, conducted data analysis and prepared the manuscript	performed in vitro and in vivo experiments, conducted data analysis and prepared the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6354709	30552062	L.L.	2	performed part of in vitro experiments, discussed data and gave conceptual advice	performed part of in vitro experiments, discussed data and gave conceptual advice	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
6354709	30552062	P.X.M.	2	assisted in the experiment design and performance, discussed and analyzed data and gave conceptual advice	assisted in the experiment design and performance, discussed and analyzed data and gave conceptual advice	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation|Methodology	YES
6354709	30552062	S.T.	2	performed in vitro and in vivo experiments, conducted data analysis and prepared the manuscript	performed in vitro and in vivo experiments, conducted data analysis and prepared the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6354709	30552062	S.X.	2	assisted in the experiment design and performance, discussed and analyzed data and gave conceptual advice	assisted in the experiment design and performance, discussed and analyzed data and gave conceptual advice	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation|Methodology	YES
6354709	30552062	W.G.	2	performed in vitro and in vivo experiments, conducted data analysis and prepared the manuscript	performed in vitro and in vivo experiments, conducted data analysis and prepared the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6354709	30552062	Y.E.C.	2	assisted in the experiment design and performance, discussed and analyzed data and gave conceptual advice	assisted in the experiment design and performance, discussed and analyzed data and gave conceptual advice	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation|Methodology	YES
6354709	30552062	Y.G.	2	performed part of in vitro experiments, discussed data and gave conceptual advice	performed part of in vitro experiments, discussed data and gave conceptual advice	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
6354709	30552062	Y.L.	2	assisted in the experiment design and performance, discussed and analyzed data and gave conceptual advice	assisted in the experiment design and performance, discussed and analyzed data and gave conceptual advice	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation|Methodology	YES
6354709	30552062	Z.W.	2	generated the hypotheses, developed the experimental design and concept of the study, supervised the experimental work, obtained funding, and wrote the manuscript	generated the hypotheses, developed the experimental design and concept of the study, supervised the experimental work, obtained funding, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Funding acquisition|Investigation|Methodology|Supervision|Writing - Original Draft	YES
6161967	29294196	Both authors	2	read and approved the final manuscript|have reviewed and approved the final version of this manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6161967	29294196	Both authors	2	read and approved the final manuscript|have reviewed and approved the final version of this manuscript	have reviewed and approved the final version of this manuscript	Wrote the paper	Writing - Review & Editing	YES
6161967	29294196	JG	2	conceptualized the ideas behind this letter, and both drafted the final manuscript	conceptualized the ideas behind this letter, and both drafted the final manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
6161967	29294196	LW	2	conceptualized the ideas behind this letter, and both drafted the final manuscript	conceptualized the ideas behind this letter, and both drafted the final manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
6161967	29294196	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
4680918	26673880	All authors	2	substantially contributed to the conception and drafting of the work for important intellectual content	substantially contributed to the conception and drafting of the work for important intellectual content	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4405297	25897962	CM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405297	25897962	CM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405297	25897962	CM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405297	25897962	CM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405297	25897962	CM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405297	25897962	GS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405297	25897962	GS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405297	25897962	GS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405297	25897962	SL	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5526925	28798765	DZ	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
5526925	28798765	FB	PLoS52	revised the paper	revised the paper	Wrote the paper	Writing - Review & Editing	YES
5526925	28798765	QLi	PLoS52	performed research|analyzed data|wrote the paper	performed research	Performed the experiments	Investigation	YES
5526925	28798765	QLi	PLoS52	performed research|analyzed data|wrote the paper	analyzed data	Analyzed the data	Formal analysis	YES
5526925	28798765	QLi	PLoS52	performed research|analyzed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5526925	28798765	QLv	PLoS52	revised the paper	revised the paper	Wrote the paper	Writing - Review & Editing	YES
5526925	28798765	TQ	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
5526925	28798765	The authors	PLoS52	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	Performed the experiments	Investigation	YES
5526925	28798765	XZ	PLoS52	performed research|analyzed data	performed research	Performed the experiments	Investigation	YES
5526925	28798765	XZ	PLoS52	performed research|analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5526925	28798765	YHe	PLoS52	designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
5526925	28798765	YHu	PLoS52	designed the research|analyzed data	designed the research	Conceived and designed the experiments	Methodology	YES
5526925	28798765	YHu	PLoS52	designed the research|analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5526925	28798765	YX	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
5622359	28970459	All authors	PLoS52	critically revised, contributed with comments, and approved the final version of the manuscript	critically revised, contributed with comments, and approved the final version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5622359	28970459	Gisselle Gallego	PLoS52	contributed to study design	contributed to study design	Conceived and designed the experiments	Methodology	YES
5622359	28970459	Maria Gustafsson	PLoS52	analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5622359	28970459	Maria Gustafsson	PLoS52	analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5622359	28970459	Sofia Mattsson	PLoS52	contributed to study design|analyzed the data	contributed to study design	Conceived and designed the experiments	Methodology	YES
5622359	28970459	Sofia Mattsson	PLoS52	contributed to study design|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5607579	28931406	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5607579	28931406	BC	2	provided clinical care and participated in data collection and data entry	provided clinical care and participated in data collection and data entry	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Investigation|Resources	YES
5607579	28931406	CB	2	provided clinical care and participated in data collection and data entry|provided critical inputs for writing the manuscript	provided clinical care and participated in data collection and data entry	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Investigation|Resources	YES
5607579	28931406	CB	2	provided clinical care and participated in data collection and data entry|provided critical inputs for writing the manuscript	provided critical inputs for writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5607579	28931406	CM	2	conceived study|wrote the manuscript|conducted main statistical analyses	conceived study	Conceived and designed the experiments	Conceptualization	YES
5607579	28931406	CM	2	conceived study|wrote the manuscript|conducted main statistical analyses	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5607579	28931406	CM	2	conceived study|wrote the manuscript|conducted main statistical analyses	conducted main statistical analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5607579	28931406	EC	2	provided clinical care and participated in data collection and data entry	provided clinical care and participated in data collection and data entry	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Investigation|Resources	YES
5607579	28931406	FT	2	provided clinical care and participated in data collection and data entry	provided clinical care and participated in data collection and data entry	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Investigation|Resources	YES
5607579	28931406	WM	2	conducted main statistical analyses	conducted main statistical analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4477191	26180811	Wenjing Zhang	2	made equal contribution to this paper	made equal contribution to this paper	-	-	NO
4477191	26180811	Xun Yang	2	made equal contribution to this paper	made equal contribution to this paper	-	-	NO
5260074	28155654	DS	2	designed the methods and experimental setup|wrote the manuscript	designed the methods and experimental setup	Conceived and designed the experiments|Performed the experiments	Methodology	YES
5260074	28155654	DS	2	designed the methods and experimental setup|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5260074	28155654	SD	2	designed the methods and experimental setup|carried out the implementation of the various methods|developed the webserver|wrote the manuscript	designed the methods and experimental setup	Conceived and designed the experiments|Performed the experiments	Methodology	YES
5260074	28155654	SD	2	designed the methods and experimental setup|carried out the implementation of the various methods|developed the webserver|wrote the manuscript	carried out the implementation of the various methods	Performed the experiments	Investigation	YES
5260074	28155654	SD	2	designed the methods and experimental setup|carried out the implementation of the various methods|developed the webserver|wrote the manuscript	developed the webserver	Contributed reagents/materials/analysis tools	Software	YES
5260074	28155654	SD	2	designed the methods and experimental setup|carried out the implementation of the various methods|developed the webserver|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5260074	28155654	SM	2	developed the webserver	developed the webserver	Contributed reagents/materials/analysis tools	Software	YES
4076618	24987486	Andreas Roth	7	Revision of manuscript	Revision of manuscript	Wrote the paper	Writing - Review & Editing	YES
4076618	24987486	Andreas Wagner	7	Analysis and interpretation of data, preparation of manuscript	Analysis and interpretation of data, preparation of manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4076618	24987486	Christoph Windisch	7	Design of the study, and preparation of the manuscript	Design of the study, and preparation of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4076618	24987486	Eric Rohner	7	Analysis and interpretation of data, preparation of manuscript	Analysis and interpretation of data, preparation of manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4076618	24987486	Georg Matziolis	7	Analysis and interpretation of data, preparation of manuscript	Analysis and interpretation of data, preparation of manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4076618	24987486	Markus Wagner	7	Analysis and interpretation of data, preparation of manuscript	Analysis and interpretation of data, preparation of manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4076618	24987486	Werner Kolb	7	Design of the study	Design of the study	Conceived and designed the experiments	Methodology	YES
4684576	26685125	AB	2	contributed to data collection|contributed to data analysis	contributed to data collection	Performed the experiments	Investigation	YES
4684576	26685125	AB	2	contributed to data collection|contributed to data analysis	contributed to data analysis	Analyzed the data	Formal analysis	YES
4684576	26685125	CJH	2	contributed to data analysis	contributed to data analysis	Analyzed the data	Formal analysis	YES
4684576	26685125	FT	2	contributed to data collection	contributed to data collection	Performed the experiments	Investigation	YES
4684576	26685125	HP	2	contributed to data collection	contributed to data collection	Performed the experiments	Investigation	YES
4684576	26685125	LFJ	2	contributed to data analysis|drafted the manuscript with inputs from all authors	contributed to data analysis	Analyzed the data	Formal analysis	YES
4684576	26685125	LFJ	2	contributed to data analysis|drafted the manuscript with inputs from all authors	drafted the manuscript with inputs from all authors	Wrote the paper	Writing - Original Draft	YES
4684576	26685125	MC	2	contributed to data analysis	contributed to data analysis	Analyzed the data	Formal analysis	YES
4684576	26685125	MPF	2	contributed to data collection	contributed to data collection	Performed the experiments	Investigation	YES
4684576	26685125	MS	2	contributed to data analysis	contributed to data analysis	Analyzed the data	Formal analysis	YES
4684576	26685125	RED	2	contributed to data analysis	contributed to data analysis	Analyzed the data	Formal analysis	YES
4684576	26685125	RL	2	contributed to data collection	contributed to data collection	Performed the experiments	Investigation	YES
4684576	26685125	RW	2	contributed to data collection	contributed to data collection	Performed the experiments	Investigation	YES
6161968	29359252	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6161968	29359252	LVK	2	wrote and contributed to the paper	wrote and contributed to the paper	Wrote the paper	Writing - Original Draft	YES
6161968	29359252	MB	2	wrote and contributed to the paper	wrote and contributed to the paper	Wrote the paper	Writing - Original Draft	YES
6161968	29359252	MFJ	2	wrote and contributed to the paper	wrote and contributed to the paper	Wrote the paper	Writing - Original Draft	YES
6161968	29359252	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
4405336	25898316	EP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405336	25898316	EP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405336	25898316	EP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405336	25898316	EP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405336	25898316	IS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4405336	25898316	IS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405336	25898316	KM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4405336	25898316	KM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405336	25898316	LG	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4405336	25898316	NJM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405336	25898316	NJM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405336	25898316	NJM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405336	25898316	NJM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405336	25898316	RG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405336	25898316	RG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405336	25898316	RG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405336	25898316	RG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6354711	30555043	DAS	2	supervised the histological experiments and commented on draft manuscript	supervised the histological experiments and commented on draft manuscript	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Original Draft	YES
6354711	30555043	DMC	2	supervised all experiments, performed electrophysiological recordings, wrote first draft of the manuscript, performed all statistical analyses, prepared figures, edited and finalised manuscript	supervised all experiments, performed electrophysiological recordings, wrote first draft of the manuscript, performed all statistical analyses, prepared figures, edited and finalised manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Supervision|Visualization|Writing - Original Draft|Writing - Review & Editing	YES
6354711	30555043	EM	2	performed the histological staining and counting of microglia and provided feedback on draft manuscript	performed the histological staining and counting of microglia and provided feedback on draft manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6354711	30555043	FAE	2	obtained funding, designed experiments, edited and finalised manuscript	obtained funding, designed experiments, edited and finalised manuscript	Conceived and designed the experiments|Wrote the paper	Funding acquisition|Methodology|Writing - Review & Editing	YES
6354711	30555043	FC	2	designed and supervised the behavioural experiments and provided comments on the draft manuscript	designed and supervised the behavioural experiments and provided comments on the draft manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Original Draft	YES
6354711	30555043	FM	2	performed ltp experiments at 2 and 4 months of age	performed ltp experiments at 2 and 4 months of age	Performed the experiments	Investigation	YES
6354711	30555043	GB	2	carried out histological staining and quantification of plaques	carried out histological staining and quantification of plaques	Performed the experiments	Investigation	YES
6354711	30555043	JCR	2	developed the mouse model and comments on the draft manuscript	developed the mouse model and comments on the draft manuscript	Performed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
6354711	30555043	KY	2	performed the ltp experiments at 24 months	performed the ltp experiments at 24 months	Performed the experiments	Investigation	YES
6354711	30555043	LM	2	provided training and supervision of all behavioural experiments	provided training and supervision of all behavioural experiments	-	Supervision	YES
6354711	30555043	MANS	2	performed behavioural experiments at 4 and 8 months of age	performed behavioural experiments at 4 and 8 months of age	Performed the experiments	Investigation	YES
6354711	30555043	OTJ	2	performed patch clamp experiments for ipscs at 4 months of age	performed patch clamp experiments for ipscs at 4 months of age	Performed the experiments	Investigation	YES
6354711	30555043	PH	2	carried out the chemical ltp experiments and comments on draft manuscript	carried out the chemical ltp experiments and comments on draft manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6354711	30555043	RW	2	performed the microglial histology and counting for the tpm mice	performed the microglial histology and counting for the tpm mice	Performed the experiments	Investigation	YES
6354711	30555043	TAB	2	carried out behavioural experiments and analysis and comments on draft manuscript	carried out behavioural experiments and analysis and comments on draft manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6354711	30555043	TH	2	performed ltp and behavioural experiments at 4 months of age	performed ltp and behavioural experiments at 4 months of age	Performed the experiments	Investigation	YES
6354711	30555043	WL	2	performed the ltp experiments at 12 and 18 months of age and comments on draft manuscript	performed the ltp experiments at 12 and 18 months of age and comments on draft manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5526928	28798759	FY	2	analyzed the results	analyzed the results	Analyzed the data	Formal analysis	YES
5526928	28798759	GJ	2	conceived the experiments|collected the samples	conceived the experiments	Conceived and designed the experiments	Conceptualization	YES
5526928	28798759	GJ	2	conceived the experiments|collected the samples	collected the samples	Performed the experiments	Investigation	YES
5526928	28798759	MZ	2	collected the samples|conducted the experiments	collected the samples	Performed the experiments	Investigation	YES
5526928	28798759	MZ	2	collected the samples|conducted the experiments	conducted the experiments	Performed the experiments	Investigation	YES
5526928	28798759	XZ	2	conceived the experiments	conceived the experiments	Conceived and designed the experiments	Conceptualization	YES
5526928	28798759	YB	2	analyzed the results|wrote the manuscript	analyzed the results	Analyzed the data	Formal analysis	YES
5526928	28798759	YB	2	analyzed the results|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5526928	28798759	YD	2	conceived the experiments|collected the samples|conducted the experiments|analyzed the results|wrote the manuscript	conceived the experiments	Conceived and designed the experiments	Conceptualization	YES
5526928	28798759	YD	2	conceived the experiments|collected the samples|conducted the experiments|analyzed the results|wrote the manuscript	collected the samples	Performed the experiments	Investigation	YES
5526928	28798759	YD	2	conceived the experiments|collected the samples|conducted the experiments|analyzed the results|wrote the manuscript	conducted the experiments	Performed the experiments	Investigation	YES
5526928	28798759	YD	2	conceived the experiments|collected the samples|conducted the experiments|analyzed the results|wrote the manuscript	analyzed the results	Analyzed the data	Formal analysis	YES
5526928	28798759	YD	2	conceived the experiments|collected the samples|conducted the experiments|analyzed the results|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5639754	29025433	AIS	2	purified and characterized the compounds	purified and characterized the compounds	Performed the experiments	Investigation	YES
5639754	29025433	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5639754	29025433	HRR	2	implemented the study and analyzed results|drafted the manuscript	implemented the study and analyzed results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5639754	29025433	HRR	2	implemented the study and analyzed results|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5639754	29025433	JB	2	purified and characterized the compounds	purified and characterized the compounds	Performed the experiments	Investigation	YES
5639754	29025433	JTO	2	implemented the study and analyzed results|drafted the manuscript	implemented the study and analyzed results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5639754	29025433	JTO	2	implemented the study and analyzed results|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5639754	29025433	MLS	2	implemented the study and analyzed results	implemented the study and analyzed results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5622360	28970460	A.O.	2	created the survey tool and interview schedule	created the survey tool and interview schedule	Performed the experiments	Investigation	YES
5622360	28970460	D.B.	2	created the survey tool and interview schedule	created the survey tool and interview schedule	Performed the experiments	Investigation	YES
5622360	28970460	N.P.	2	conceived and designed the study|revised the study critically and approved the final version for publication	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5622360	28970460	N.P.	2	conceived and designed the study|revised the study critically and approved the final version for publication	revised the study critically and approved the final version for publication	Wrote the paper	Writing - Review & Editing	YES
5622360	28970460	P.C.	2	interpreted data from the study and wrote the paper	interpreted data from the study and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5622360	28970460	R.K.	2	conceived and designed the study|revised the study critically and approved the final version for publication	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5622360	28970460	R.K.	2	conceived and designed the study|revised the study critically and approved the final version for publication	revised the study critically and approved the final version for publication	Wrote the paper	Writing - Review & Editing	YES
5260093	28155657	HK	PLoS5	Supervised the research	Supervised the research	-	Supervision	YES
5260093	28155657	HPL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5260093	28155657	LJKW	PLoS5	Supervised the research|Conceived the experiments	Supervised the research	-	Supervision	YES
5260093	28155657	LJKW	PLoS5	Supervised the research|Conceived the experiments	Conceived the experiments	Conceived and designed the experiments	Conceptualization	YES
5260093	28155657	SG	PLoS5	Supervised the research|Conceived the experiments	Supervised the research	-	Supervision	YES
5260093	28155657	SG	PLoS5	Supervised the research|Conceived the experiments	Conceived the experiments	Conceived and designed the experiments	Conceptualization	YES
5260093	28155657	SKN	PLoS5	Supervised the research	Supervised the research	-	Supervision	YES
5260093	28155657	SP	PLoS5	Supervised the research	Supervised the research	-	Supervision	YES
5260093	28155657	TH	PLoS5	Designed the experiments and analyses|Performed the experiments|Analyzed the data|Wrote the paper	Designed the experiments and analyses	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5260093	28155657	TH	PLoS5	Designed the experiments and analyses|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
5260093	28155657	TH	PLoS5	Designed the experiments and analyses|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5260093	28155657	TH	PLoS5	Designed the experiments and analyses|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5260093	28155657	YH	PLoS5	Designed the experiments and analyses|Performed the experiments|Analyzed the data|Wrote the paper	Designed the experiments and analyses	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5260093	28155657	YH	PLoS5	Designed the experiments and analyses|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
5260093	28155657	YH	PLoS5	Designed the experiments and analyses|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5260093	28155657	YH	PLoS5	Designed the experiments and analyses|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4685962	26690303	BK	PLoS52	contributed to the conception of the analysis|contributed to data collection and cleaning|reviewed and contributed to the manuscript	contributed to the conception of the analysis	Conceived and designed the experiments	Conceptualization	YES
4685962	26690303	BK	PLoS52	contributed to the conception of the analysis|contributed to data collection and cleaning|reviewed and contributed to the manuscript	contributed to data collection and cleaning	Performed the experiments	Data curation|Investigation	YES
4685962	26690303	BK	PLoS52	contributed to the conception of the analysis|contributed to data collection and cleaning|reviewed and contributed to the manuscript	reviewed and contributed to the manuscript	Wrote the paper	Writing - Review & Editing	YES
4685962	26690303	CW	PLoS52	contributed to the conception of the analysis|analyzed the data|reviewed and contributed to the manuscript	contributed to the conception of the analysis	Conceived and designed the experiments	Conceptualization	YES
4685962	26690303	CW	PLoS52	contributed to the conception of the analysis|analyzed the data|reviewed and contributed to the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
4685962	26690303	CW	PLoS52	contributed to the conception of the analysis|analyzed the data|reviewed and contributed to the manuscript	reviewed and contributed to the manuscript	Wrote the paper	Writing - Review & Editing	YES
4685962	26690303	EJA	PLoS52	contributed to the conception of the analysis|reviewed and contributed to the manuscript|gave overall technical oversight and leadership for the analytic process and manuscript writing	contributed to the conception of the analysis	Conceived and designed the experiments	Conceptualization	YES
4685962	26690303	EJA	PLoS52	contributed to the conception of the analysis|reviewed and contributed to the manuscript|gave overall technical oversight and leadership for the analytic process and manuscript writing	reviewed and contributed to the manuscript	Wrote the paper	Writing - Review & Editing	YES
4685962	26690303	EJA	PLoS52	contributed to the conception of the analysis|reviewed and contributed to the manuscript|gave overall technical oversight and leadership for the analytic process and manuscript writing	gave overall technical oversight and leadership for the analytic process and manuscript writing	Wrote the paper	Supervision|Writing - Original Draft	YES
4685962	26690303	FKJ	PLoS52	contributed to the conception of the analysis|contributed to data collection and cleaning|reviewed and contributed to the manuscript	contributed to the conception of the analysis	Conceived and designed the experiments	Conceptualization	YES
4685962	26690303	FKJ	PLoS52	contributed to the conception of the analysis|contributed to data collection and cleaning|reviewed and contributed to the manuscript	contributed to data collection and cleaning	Performed the experiments	Data curation|Investigation	YES
4685962	26690303	FKJ	PLoS52	contributed to the conception of the analysis|contributed to data collection and cleaning|reviewed and contributed to the manuscript	reviewed and contributed to the manuscript	Wrote the paper	Writing - Review & Editing	YES
4685962	26690303	GA	PLoS52	contributed to the conception of the analysis|contributed to data collection and cleaning|reviewed and contributed to the manuscript	contributed to the conception of the analysis	Conceived and designed the experiments	Conceptualization	YES
4685962	26690303	GA	PLoS52	contributed to the conception of the analysis|contributed to data collection and cleaning|reviewed and contributed to the manuscript	contributed to data collection and cleaning	Performed the experiments	Data curation|Investigation	YES
4685962	26690303	GA	PLoS52	contributed to the conception of the analysis|contributed to data collection and cleaning|reviewed and contributed to the manuscript	reviewed and contributed to the manuscript	Wrote the paper	Writing - Review & Editing	YES
4685962	26690303	HNB	PLoS52	contributed to the conception of the analysis|contributed to data collection and cleaning|wrote the manuscript|reviewed and contributed to the manuscript	contributed to the conception of the analysis	Conceived and designed the experiments	Conceptualization	YES
4685962	26690303	HNB	PLoS52	contributed to the conception of the analysis|contributed to data collection and cleaning|wrote the manuscript|reviewed and contributed to the manuscript	contributed to data collection and cleaning	Performed the experiments	Data curation|Investigation	YES
4685962	26690303	HNB	PLoS52	contributed to the conception of the analysis|contributed to data collection and cleaning|wrote the manuscript|reviewed and contributed to the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4685962	26690303	HNB	PLoS52	contributed to the conception of the analysis|contributed to data collection and cleaning|wrote the manuscript|reviewed and contributed to the manuscript	reviewed and contributed to the manuscript	Wrote the paper	Writing - Review & Editing	YES
4685962	26690303	MFP	PLoS52	contributed to data collection and cleaning|reviewed and contributed to the manuscript	contributed to data collection and cleaning	Performed the experiments	Data curation|Investigation	YES
4685962	26690303	MFP	PLoS52	contributed to data collection and cleaning|reviewed and contributed to the manuscript	reviewed and contributed to the manuscript	Wrote the paper	Writing - Review & Editing	YES
5133731	27942382	Gokhan Artas	7	Data collections, data analysis	Data collections, data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5133731	27942382	Kazim Duman	7	Study design, writing	Study design, writing	Conceived and designed the experiments|Wrote the paper	Methodology	YES
5133731	27942382	Mustafa Girgin	7	Data collections, data analysis	Data collections, data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6161969	30178112	AB	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
6161969	30178112	AC	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
6161969	30178112	AD	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
6161969	30178112	AF	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
6161969	30178112	AG	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
6161969	30178112	AHL	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
6161969	30178112	AHS	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
6161969	30178112	AM-S	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
6161969	30178112	APC	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
6161969	30178112	AR	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
6161969	30178112	AS	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
6161969	30178112	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6161969	30178112	BE	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
6161969	30178112	BL	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
6161969	30178112	BM	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
6161969	30178112	BS	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
6161969	30178112	BV	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
6161969	30178112	CC	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
6161969	30178112	CH	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
6161969	30178112	CL	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
6161969	30178112	COD	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
6161969	30178112	CS	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
6161969	30178112	DH-M	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
6161969	30178112	ERL	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
6161969	30178112	ES	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
6161969	30178112	EV	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
6161969	30178112	EYWC	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
6161969	30178112	GK	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
6161969	30178112	GMG	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
6161969	30178112	HH	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
6161969	30178112	JC	2	designed the study|were involved with data collection|were involved in the draft manuscript and initial review	designed the study	Conceived and designed the experiments	Methodology	YES
6161969	30178112	JC	2	designed the study|were involved with data collection|were involved in the draft manuscript and initial review	were involved with data collection	Performed the experiments	Investigation	YES
6161969	30178112	JC	2	designed the study|were involved with data collection|were involved in the draft manuscript and initial review	were involved in the draft manuscript and initial review	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6161969	30178112	JG	2	were involved with data collection|were involved with data collection|were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
6161969	30178112	JG	2	were involved with data collection|were involved with data collection|were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
6161969	30178112	JG	2	were involved with data collection|were involved with data collection|were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
6161969	30178112	JKR	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
6161969	30178112	JV	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
6161969	30178112	KS	2	were involved with data collection|were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
6161969	30178112	KS	2	were involved with data collection|were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
6161969	30178112	LT	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
6161969	30178112	MA	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
6161969	30178112	MB	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
6161969	30178112	MBa	2	designed the study|were involved in the draft manuscript and initial review	designed the study	Conceived and designed the experiments	Methodology	YES
6161969	30178112	MBa	2	designed the study|were involved in the draft manuscript and initial review	were involved in the draft manuscript and initial review	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6161969	30178112	MJG	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
6161969	30178112	MV	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
6161969	30178112	MZ	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
6161969	30178112	PCW	2	were involved in the draft manuscript and initial review	were involved in the draft manuscript and initial review	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6161969	30178112	PG	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
6161969	30178112	PP	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
6161969	30178112	PR	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
6161969	30178112	PT	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
6161969	30178112	RA	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
6161969	30178112	RB	2	designed the study|were involved with data collection|were involved in the draft manuscript and initial review	designed the study	Conceived and designed the experiments	Methodology	YES
6161969	30178112	RB	2	designed the study|were involved with data collection|were involved in the draft manuscript and initial review	were involved with data collection	Performed the experiments	Investigation	YES
6161969	30178112	RB	2	designed the study|were involved with data collection|were involved in the draft manuscript and initial review	were involved in the draft manuscript and initial review	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6161969	30178112	RD	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
6161969	30178112	REN	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
6161969	30178112	RM	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
6161969	30178112	RW	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
6161969	30178112	SC	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
6161969	30178112	SD	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
6161969	30178112	SH	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
6161969	30178112	SM	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
6161969	30178112	SS	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
6161969	30178112	TG	2	designed the study|provided data analysis|were involved in the draft manuscript and initial review	designed the study	Conceived and designed the experiments	Methodology	YES
6161969	30178112	TG	2	designed the study|provided data analysis|were involved in the draft manuscript and initial review	provided data analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6161969	30178112	TG	2	designed the study|provided data analysis|were involved in the draft manuscript and initial review	were involved in the draft manuscript and initial review	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6161969	30178112	TN	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
6161969	30178112	UL	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
6161969	30178112	VK	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
6161969	30178112	YB	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
6161969	30178112	YO	2	were involved with data collection|were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
6161969	30178112	YO	2	were involved with data collection|were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
6161969	30178112	YT	2	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
5529344	28798760	AG	2	conceptualized the article|wrote the article and did final editing	conceptualized the article	Conceived and designed the experiments	Conceptualization	YES
5529344	28798760	AG	2	conceptualized the article|wrote the article and did final editing	wrote the article and did final editing	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5529344	28798760	AL	2	conceptualized the article	conceptualized the article	Conceived and designed the experiments	Conceptualization	YES
5529344	28798760	All authors	2	have made intellectual contribution to the article, and approved it for publication	have made intellectual contribution to the article, and approved it for publication	-	-	NO
5529344	28798760	MS	2	conceptualized the article|wrote the article and did final editing	conceptualized the article	Conceived and designed the experiments	Conceptualization	YES
5529344	28798760	MS	2	conceptualized the article|wrote the article and did final editing	wrote the article and did final editing	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4405337	25897961	ALC	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405337	25897961	ALC	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405337	25897961	BBF	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4405337	25897961	BBF	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405337	25897961	BK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405337	25897961	EJ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405337	25897961	EM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405337	25897961	EM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405337	25897961	EM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405337	25897961	FMA	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405337	25897961	FMA	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405337	25897961	RR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405337	25897961	RR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405337	25897961	RR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405337	25897961	RR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405337	25897961	WK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5640939	29029637	All authors	2	provided critical review|read and approved the final manuscript	provided critical review	-	-	NO
5640939	29029637	All authors	2	provided critical review|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5640939	29029637	BC	2	carried out the laboratory work and participated in the data collection	carried out the laboratory work and participated in the data collection	Performed the experiments	Investigation	YES
5640939	29029637	GI	2	carried out the laboratory work and participated in the data collection	carried out the laboratory work and participated in the data collection	Performed the experiments	Investigation	YES
5640939	29029637	JI	2	conceived the study and coordinated the study efforts	conceived the study and coordinated the study efforts	Conceived and designed the experiments	Conceptualization|Project administration	YES
5640939	29029637	OA	2	conceived the study and coordinated the study efforts	conceived the study and coordinated the study efforts	Conceived and designed the experiments	Conceptualization|Project administration	YES
5640939	29029637	PJK	2	conceived the study and coordinated the study efforts	conceived the study and coordinated the study efforts	Conceived and designed the experiments	Conceptualization|Project administration	YES
5640939	29029637	PO	2	conceived the study and coordinated the study efforts	conceived the study and coordinated the study efforts	Conceived and designed the experiments	Conceptualization|Project administration	YES
5640939	29029637	RM	2	conceived the study and coordinated the study efforts	conceived the study and coordinated the study efforts	Conceived and designed the experiments	Conceptualization|Project administration	YES
5640939	29029637	SA	2	conceived the study and coordinated the study efforts	conceived the study and coordinated the study efforts	Conceived and designed the experiments	Conceptualization|Project administration	YES
5640939	29029637	STM	2	developed the analysis strategy, carried out the statistical analyses and prepared the manuscript	developed the analysis strategy, carried out the statistical analyses and prepared the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5134081	27942379	Fergus Gardiner	7	conceived the research, and developed the research design, data collection, and performed the research analysis	conceived the research, and developed the research design, data collection, and performed the research analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation|Methodology	YES
5134081	27942379	Shaun Zhai	7	helped conceive the research methodology, performed secondary research analysis, and reviewed and validated the medical record data after initial review, as outlined above	helped conceive the research methodology, performed secondary research analysis, and reviewed and validated the medical record data after initial review, as outlined above	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation|Methodology|Validation	YES
5622361	28970461	All authors	2	helped to write the manuscript	helped to write the manuscript	Wrote the paper	Writing - Original Draft	YES
5622361	28970461	International Drug Discovery	2	designed the survey tool used in the course	designed the survey tool used in the course	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5622361	28970461	J.R.C.	2	designed the survey tool used in the course	designed the survey tool used in the course	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5260097	28155723	DCY	2	helped with some web pages	helped with some web pages	Contributed reagents/materials/analysis tools	Software	YES
5260097	28155723	FT	2	helped most of the rna seq analysis and evaluation	helped most of the rna seq analysis and evaluation	Performed the experiments	Investigation	YES
5260097	28155723	GG	2	conceived this work|wrote the manuscript	conceived this work	Conceived and designed the experiments	Conceptualization	YES
5260097	28155723	GG	2	conceived this work|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5260097	28155723	LK	2	helped with the infrastructure of web server	helped with the infrastructure of web server	Contributed reagents/materials/analysis tools	Software	YES
5260097	28155723	MH	2	implemented the local strategy and built the web server|wrote the manuscript	implemented the local strategy and built the web server	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5260097	28155723	MH	2	implemented the local strategy and built the web server|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5260097	28155723	SJ	2	helped with novel transcript model	helped with novel transcript model	Performed the experiments	Methodology	YES
4689151	26700845	ED	2	conceptualized and researched the paper and were the lead writers	conceptualized and researched the paper and were the lead writers	Conceived and designed the experiments|Wrote the paper	Conceptualization	YES
4689151	26700845	LH	2	contributed original ideas and provided detailed comments on the paper	contributed original ideas and provided detailed comments on the paper	Conceived and designed the experiments	Conceptualization	YES
4689151	26700845	MG	2	contributed original ideas and provided detailed comments on the paper	contributed original ideas and provided detailed comments on the paper	Conceived and designed the experiments	Conceptualization	YES
4689151	26700845	ML	2	conceptualized and researched the paper and were the lead writers	conceptualized and researched the paper and were the lead writers	Conceived and designed the experiments|Wrote the paper	Conceptualization	YES
4689151	26700845	QAK	2	contributed original ideas and provided detailed comments on the paper	contributed original ideas and provided detailed comments on the paper	Conceived and designed the experiments	Conceptualization	YES
4689151	26700845	RW	2	conceptualized and researched the paper and were the lead writers	conceptualized and researched the paper and were the lead writers	Conceived and designed the experiments|Wrote the paper	Conceptualization	YES
4405339	25898344	AM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405339	25898344	AM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405339	25898344	AM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405339	25898344	AM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405339	25898344	CL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405339	25898344	CL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405339	25898344	CL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405339	25898344	CL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405339	25898344	GG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405339	25898344	GG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405339	25898344	GG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405339	25898344	GG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405339	25898344	JPF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405339	25898344	JPF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405339	25898344	JPF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405339	25898344	JPF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405339	25898344	SF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405339	25898344	SF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405339	25898344	SF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405339	25898344	SF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5134085	27942381	Bliss J. Chang	2	conceived and wrote the manuscript	conceived and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
6161976	29713845	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6161976	29713845	ES	2	performed data collection, and interpretation of the findings	performed data collection, and interpretation of the findings	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6161976	29713845	MB	2	worked on the conception and design of the study, interpreted the results and drafted the manuscript	worked on the conception and design of the study, interpreted the results and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
6161976	29713845	MP	2	worked on the conception and design of the study, interpreted the results and drafted the manuscript	worked on the conception and design of the study, interpreted the results and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
6161976	29713845	PR	2	performed data collection, and interpretation of the findings	performed data collection, and interpretation of the findings	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6161976	29713845	PW	2	worked on the conception and design of the study, interpreted the results and drafted the manuscript	worked on the conception and design of the study, interpreted the results and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
6161976	29713845	RB	2	performed data collection, and interpretation of the findings	performed data collection, and interpretation of the findings	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6161976	29713845	SM	2	performed data collection, and interpretation of the findings	performed data collection, and interpretation of the findings	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6161976	29713845	TG	2	worked on the conception and design of the study, interpreted the results and drafted the manuscript|performed the analyses	worked on the conception and design of the study, interpreted the results and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
6161976	29713845	TG	2	worked on the conception and design of the study, interpreted the results and drafted the manuscript|performed the analyses	performed the analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6161976	29713845	WM	2	performed data collection, and interpretation of the findings	performed data collection, and interpretation of the findings	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5529362	28798767	AC	PLoS52	analyzed data and discussed results	analyzed data and discussed results	Analyzed the data	Formal analysis	YES
5529362	28798767	All authors	PLoS52	contributed to improving the paper and approved the final manuscript	contributed to improving the paper and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5529362	28798767	IF	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
5529362	28798767	LB	PLoS52	designed research|performed research|analyzed data and discussed results|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
5529362	28798767	LB	PLoS52	designed research|performed research|analyzed data and discussed results|wrote the paper	performed research	Performed the experiments	Investigation	YES
5529362	28798767	LB	PLoS52	designed research|performed research|analyzed data and discussed results|wrote the paper	analyzed data and discussed results	Analyzed the data	Formal analysis	YES
5529362	28798767	LB	PLoS52	designed research|performed research|analyzed data and discussed results|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5529362	28798767	LL	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
5529362	28798767	MB	PLoS52	designed research|analyzed data and discussed results|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
5529362	28798767	MB	PLoS52	designed research|analyzed data and discussed results|wrote the paper	analyzed data and discussed results	Analyzed the data	Formal analysis	YES
5529362	28798767	MB	PLoS52	designed research|analyzed data and discussed results|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5529362	28798767	MG	PLoS52	designed research|performed research	designed research	Conceived and designed the experiments	Methodology	YES
5529362	28798767	MG	PLoS52	designed research|performed research	performed research	Performed the experiments	Investigation	YES
5529362	28798767	MP	PLoS52	performed research|analyzed data and discussed results|wrote the paper	performed research	Performed the experiments	Investigation	YES
5529362	28798767	MP	PLoS52	performed research|analyzed data and discussed results|wrote the paper	analyzed data and discussed results	Analyzed the data	Formal analysis	YES
5529362	28798767	MP	PLoS52	performed research|analyzed data and discussed results|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5669010	29096670	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5669010	29096670	BG	2	enrolled and followed participants and collected data	enrolled and followed participants and collected data	Performed the experiments	Investigation	YES
5669010	29096670	BW	2	performed the drug level assays and interpreted the data	performed the drug level assays and interpreted the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5669010	29096670	JSGM	2	contributed to the design of the study, data analysis and interpretation	contributed to the design of the study, data analysis and interpretation	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Methodology|Resources	YES
5669010	29096670	MH	2	contributed to the design of the study and to data analysis and interpretation, and wrote the manuscript	contributed to the design of the study and to data analysis and interpretation, and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Original Draft	YES
5669010	29096670	MWH	2	designed the study, recruited and followed study participants, and contributed to data analysis and interpretation	designed the study, recruited and followed study participants, and contributed to data analysis and interpretation	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5669010	29096670	PRH	2	performed the drug level and genotypic assays and interpreted the data	performed the drug level and genotypic assays and interpreted the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4405340	25897972	AM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405340	25897972	AM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405340	25897972	AM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405340	25897972	AM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405340	25897972	BOB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405340	25897972	BOB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405340	25897972	BOB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405340	25897972	LA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405340	25897972	LA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405340	25897972	LA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405340	25897972	LA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405340	25897972	MLR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405340	25897972	MLR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405340	25897972	MLR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405340	25897972	MLR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405340	25897972	PPP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5260101	28155658	HYK	2	conducted the experiments|interpreted and analyzed the experimental data|wrote the manuscript	conducted the experiments	Performed the experiments	Investigation	YES
5260101	28155658	HYK	2	conducted the experiments|interpreted and analyzed the experimental data|wrote the manuscript	interpreted and analyzed the experimental data	Analyzed the data	Formal analysis	YES
5260101	28155658	HYK	2	conducted the experiments|interpreted and analyzed the experimental data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5260101	28155658	TLM	2	conceptualized the project|designed the study	conceptualized the project	Conceived and designed the experiments	Conceptualization	YES
5260101	28155658	TLM	2	conceptualized the project|designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5260101	28155658	VK	2	designed the study|performed in silico analyses|interpreted and analyzed the experimental data|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5260101	28155658	VK	2	designed the study|performed in silico analyses|interpreted and analyzed the experimental data|wrote the manuscript	performed in silico analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5260101	28155658	VK	2	designed the study|performed in silico analyses|interpreted and analyzed the experimental data|wrote the manuscript	interpreted and analyzed the experimental data	Analyzed the data	Formal analysis	YES
5260101	28155658	VK	2	designed the study|performed in silico analyses|interpreted and analyzed the experimental data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5260101	28155658	WLT	2	conducted the experiments|interpreted and analyzed the experimental data	conducted the experiments	Performed the experiments	Investigation	YES
5260101	28155658	WLT	2	conducted the experiments|interpreted and analyzed the experimental data	interpreted and analyzed the experimental data	Analyzed the data	Formal analysis	YES
5260101	28155658	WPY	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
6161977	29730832	AHY	2	were involved in the writing, editing, and reviewing of this manuscript	were involved in the writing, editing, and reviewing of this manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6161977	29730832	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6161977	29730832	DHM	2	were involved in the writing, editing, and reviewing of this manuscript	were involved in the writing, editing, and reviewing of this manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6161977	29730832	EV	2	were involved in the writing, editing, and reviewing of this manuscript	were involved in the writing, editing, and reviewing of this manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6161977	29730832	FC	2	were involved in the writing, editing, and reviewing of this manuscript	were involved in the writing, editing, and reviewing of this manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6161977	29730832	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5622363	28970463	A.A.N.	2	conducted statistical analysis of the research tool and finalized the questionnaire|analyzed the data and conducted statistical analysis|analyzed the data and conducted statistical analysis|wrote the introduction and methodology section|wrote the abstract and conclusion	conducted statistical analysis of the research tool and finalized the questionnaire	Analyzed the data	Formal analysis	YES
5622363	28970463	A.A.N.	2	conducted statistical analysis of the research tool and finalized the questionnaire|analyzed the data and conducted statistical analysis|analyzed the data and conducted statistical analysis|wrote the introduction and methodology section|wrote the abstract and conclusion	analyzed the data and conducted statistical analysis	Analyzed the data	Formal analysis	YES
5622363	28970463	A.A.N.	2	conducted statistical analysis of the research tool and finalized the questionnaire|analyzed the data and conducted statistical analysis|analyzed the data and conducted statistical analysis|wrote the introduction and methodology section|wrote the abstract and conclusion	analyzed the data and conducted statistical analysis	Analyzed the data	Formal analysis	YES
5622363	28970463	A.A.N.	2	conducted statistical analysis of the research tool and finalized the questionnaire|analyzed the data and conducted statistical analysis|analyzed the data and conducted statistical analysis|wrote the introduction and methodology section|wrote the abstract and conclusion	wrote the introduction and methodology section	Performed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5622363	28970463	A.A.N.	2	conducted statistical analysis of the research tool and finalized the questionnaire|analyzed the data and conducted statistical analysis|analyzed the data and conducted statistical analysis|wrote the introduction and methodology section|wrote the abstract and conclusion	wrote the abstract and conclusion	Wrote the paper	Writing - Original Draft	YES
5622363	28970463	F.A.A.	2	conducted the pilot study and modified the research instrument according to pilot results|wrote the abstract and conclusion|wrote the abstract and conclusion	conducted the pilot study and modified the research instrument according to pilot results	Performed the experiments	Investigation	YES
5622363	28970463	F.A.A.	2	conducted the pilot study and modified the research instrument according to pilot results|wrote the abstract and conclusion|wrote the abstract and conclusion	wrote the abstract and conclusion	Wrote the paper	Writing - Original Draft	YES
5622363	28970463	F.A.A.	2	conducted the pilot study and modified the research instrument according to pilot results|wrote the abstract and conclusion|wrote the abstract and conclusion	wrote the abstract and conclusion	Wrote the paper	Writing - Original Draft	YES
5622363	28970463	N.A.	2	conducted the pilot study and modified the research instrument according to pilot results	conducted the pilot study and modified the research instrument according to pilot results	Performed the experiments	Investigation	YES
5622363	28970463	R.A.	2	conducted the pilot study and modified the research instrument according to pilot results|analyzed the data and conducted statistical analysis	conducted the pilot study and modified the research instrument according to pilot results	Performed the experiments	Investigation	YES
5622363	28970463	R.A.	2	conducted the pilot study and modified the research instrument according to pilot results|analyzed the data and conducted statistical analysis	analyzed the data and conducted statistical analysis	Analyzed the data	Formal analysis	YES
5683524	29132400	AIH	2	together designed the study|drafted the manuscript	together designed the study	Conceived and designed the experiments	Methodology	YES
5683524	29132400	AIH	2	together designed the study|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5683524	29132400	All authors	2	contributed in data collection, analysis and manuscript preparation|read and approved the final manuscript	contributed in data collection, analysis and manuscript preparation	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft	YES
5683524	29132400	All authors	2	contributed in data collection, analysis and manuscript preparation|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5683524	29132400	CAA	2	proposed the idea|together designed the study|drafted the manuscript	proposed the idea	Conceived and designed the experiments	Conceptualization	YES
5683524	29132400	CAA	2	proposed the idea|together designed the study|drafted the manuscript	together designed the study	Conceived and designed the experiments	Methodology	YES
5683524	29132400	CAA	2	proposed the idea|together designed the study|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5683524	29132400	CAR	2	proposed the idea|together designed the study|drafted the manuscript	proposed the idea	Conceived and designed the experiments	Conceptualization	YES
5683524	29132400	CAR	2	proposed the idea|together designed the study|drafted the manuscript	together designed the study	Conceived and designed the experiments	Methodology	YES
5683524	29132400	CAR	2	proposed the idea|together designed the study|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5683524	29132400	IMT	2	together designed the study	together designed the study	Conceived and designed the experiments	Methodology	YES
5683524	29132400	JPV	2	together designed the study	together designed the study	Conceived and designed the experiments	Methodology	YES
5683524	29132400	MFA	2	proposed the idea|together designed the study|drafted the manuscript	proposed the idea	Conceived and designed the experiments	Conceptualization	YES
5683524	29132400	MFA	2	proposed the idea|together designed the study|drafted the manuscript	together designed the study	Conceived and designed the experiments	Methodology	YES
5683524	29132400	MFA	2	proposed the idea|together designed the study|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5137169	27942384	Adrian Camacho-Ortiz	7	study concept or design, data analysis or interpretation, writing the paper	study concept or design, data analysis or interpretation, writing the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
5137169	27942384	Adrian Negreros-Osuna	7	study concept or design, data collection	study concept or design, data collection	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
5137169	27942384	Elvira Garza-Gonzalez	7	study concept or design, writing the paper. Eva	study concept or design, writing the paper. Eva	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
5137169	27942384	Laura Palau-Davila	7	study concept or design, data collection, data analysis or interpretation, writing the paper	study concept or design, data collection, data analysis or interpretation, writing the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5137169	27942384	Maria Gutierrez-Delgado	7	data collection	data collection	Performed the experiments	Investigation	YES
5137169	27942384	Matias Salinas-Chapa	7	study concept or design, data collection	study concept or design, data collection	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
5137169	27942384	Reynaldo Lara-Medrano	7	study concept or design, data interpretation	study concept or design, data interpretation	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
4405342	25898207	CCW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405342	25898207	CWK	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4405342	25898207	CWK	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4405342	25898207	CYC	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4405342	25898207	CYC	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4405342	25898207	KCL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405342	25898207	KCL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405342	25898207	KCL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405342	25898207	KHH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405342	25898207	KST	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405342	25898207	KTH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405342	25898207	MLS	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405342	25898207	MLS	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405342	25898207	SHL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405342	25898207	SHL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405342	25898207	SHL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4689876	26701080	AK	2	devised the initial outline of this literature review	devised the initial outline of this literature review	Conceived and designed the experiments	Conceptualization|Formal analysis	YES
4689876	26701080	SP	2	devised the initial outline of this literature review|drafted the manuscript with the support of ak, and all authors contributed to the final copy	devised the initial outline of this literature review	Conceived and designed the experiments	Conceptualization|Formal analysis	YES
4689876	26701080	SP	2	devised the initial outline of this literature review|drafted the manuscript with the support of ak, and all authors contributed to the final copy	drafted the manuscript with the support of ak, and all authors contributed to the final copy	Wrote the paper	Writing - Original Draft	YES
5529384	28798752	All authors	2	have read and approved the final manuscript	have read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5529384	28798752	DArT	2	genotyping and revised the paper	genotyping and revised the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5529384	28798752	DC	2	participated in field trials	participated in field trials	-	-	NO
5529384	28798752	FC	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5529384	28798752	WH	2	participated in field trials	participated in field trials	-	-	NO
5529384	28798752	WZ	2	participated in field trials	participated in field trials	-	-	NO
5529384	28798752	XC	2	participated in field trials	participated in field trials	-	-	NO
5529384	28798752	YR	2	carried out the experiment and wrote the manuscript|designed the study	carried out the experiment and wrote the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5529384	28798752	YR	2	carried out the experiment and wrote the manuscript|designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5260138	28155665	CYL	2	participated in discussions and conceptualization as well as revising the draft	participated in discussions and conceptualization as well as revising the draft	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5260138	28155665	PYC	2	designed and implemented the algorithm of the methylation level	designed and implemented the algorithm of the methylation level	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5260138	28155665	SHC	2	participated in discussions and conceptualization as well as revising the draft	participated in discussions and conceptualization as well as revising the draft	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5260138	28155665	SYS	2	participated in discussions and conceptualization as well as revising the draft	participated in discussions and conceptualization as well as revising the draft	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5260138	28155665	TEA	2	website construction and implemented the tools and workflows for data visualization and deep analysis	website construction and implemented the tools and workflows for data visualization and deep analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Methodology|Software|Visualization	YES
5260138	28155665	YSC	2	designed and implemented the algorithm of the methylation level	designed and implemented the algorithm of the methylation level	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
6413339	30686755	B.A.C-C	2	performed viability studies on aml cell lines|performed western assays|performed apoptosis assays|performed cell cycle experiments	performed viability studies on aml cell lines	Performed the experiments	Investigation	YES
6413339	30686755	B.A.C-C	2	performed viability studies on aml cell lines|performed western assays|performed apoptosis assays|performed cell cycle experiments	performed western assays	Performed the experiments	Investigation	YES
6413339	30686755	B.A.C-C	2	performed viability studies on aml cell lines|performed western assays|performed apoptosis assays|performed cell cycle experiments	performed apoptosis assays	Performed the experiments	Investigation	YES
6413339	30686755	B.A.C-C	2	performed viability studies on aml cell lines|performed western assays|performed apoptosis assays|performed cell cycle experiments	performed cell cycle experiments	Performed the experiments	Investigation	YES
6413339	30686755	B.D.E.	2	designed animal efficacy studies|edited the manuscript|analyzed and interpreted data	designed animal efficacy studies	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6413339	30686755	B.D.E.	2	designed animal efficacy studies|edited the manuscript|analyzed and interpreted data	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
6413339	30686755	B.D.E.	2	designed animal efficacy studies|edited the manuscript|analyzed and interpreted data	analyzed and interpreted data	Analyzed the data	Formal analysis	YES
6413339	30686755	E.L.	2	edited the manuscript|performed viability studies on aml cell lines	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
6413339	30686755	E.L.	2	edited the manuscript|performed viability studies on aml cell lines	performed viability studies on aml cell lines	Performed the experiments	Investigation	YES
6413339	30686755	E.T.C.	2	performed in-vivo efficacy studies	performed in-vivo efficacy studies	Performed the experiments	Investigation	YES
6413339	30686755	E.Y.C.	2	performed in-vivo efficacy studies	performed in-vivo efficacy studies	Performed the experiments	Investigation	YES
6413339	30686755	H.O.S.	2	designed overall study, managed overall study and secured funding for study	designed overall study, managed overall study and secured funding for study	Conceived and designed the experiments	Funding acquisition|Methodology|Project administration	YES
6413339	30686755	M.W.	2	performed western assays	performed western assays	Performed the experiments	Investigation	YES
6413339	30686755	N.N.	2	synthesized compounds	synthesized compounds	Performed the experiments	Investigation	YES
6413339	30686755	O-T	2	wrote the manuscript|performed viability studies on aml cell lines|performed western assays|performed apoptosis assays|analyzed and interpreted data	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6413339	30686755	O-T	2	wrote the manuscript|performed viability studies on aml cell lines|performed western assays|performed apoptosis assays|analyzed and interpreted data	performed viability studies on aml cell lines	Performed the experiments	Investigation	YES
6413339	30686755	O-T	2	wrote the manuscript|performed viability studies on aml cell lines|performed western assays|performed apoptosis assays|analyzed and interpreted data	performed western assays	Performed the experiments	Investigation	YES
6413339	30686755	O-T	2	wrote the manuscript|performed viability studies on aml cell lines|performed western assays|performed apoptosis assays|analyzed and interpreted data	performed apoptosis assays	Performed the experiments	Investigation	YES
6413339	30686755	O-T	2	wrote the manuscript|performed viability studies on aml cell lines|performed western assays|performed apoptosis assays|analyzed and interpreted data	analyzed and interpreted data	Analyzed the data	Formal analysis	YES
6413339	30686755	R.G.L.	2	designed animal efficacy studies|edited the manuscript|analyzed and interpreted data	designed animal efficacy studies	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6413339	30686755	R.G.L.	2	designed animal efficacy studies|edited the manuscript|analyzed and interpreted data	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
6413339	30686755	R.G.L.	2	designed animal efficacy studies|edited the manuscript|analyzed and interpreted data	analyzed and interpreted data	Analyzed the data	Formal analysis	YES
6413339	30686755	S.E.T-A	2	performed in-vivo efficacy studies	performed in-vivo efficacy studies	Performed the experiments	Investigation	YES
6161980	29616434	All authors	2	contributed to the final manuscript|read and approved the final manuscript	contributed to the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6161980	29616434	All authors	2	contributed to the final manuscript|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6161980	29616434	JRG	2	made contributions to conception and design of the study|contributed with data acquisition|provided clinical input for data interpretation	made contributions to conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6161980	29616434	JRG	2	made contributions to conception and design of the study|contributed with data acquisition|provided clinical input for data interpretation	contributed with data acquisition	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
6161980	29616434	JRG	2	made contributions to conception and design of the study|contributed with data acquisition|provided clinical input for data interpretation	provided clinical input for data interpretation	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6161980	29616434	KEAS	2	provided clinical input for data interpretation	provided clinical input for data interpretation	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6161980	29616434	MAVM	2	performed the statistical analysis and drafted the manuscript	performed the statistical analysis and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6161980	29616434	RP	2	made contributions to conception and design of the study	made contributions to conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6161980	29616434	RS	2	made contributions to conception and design of the study	made contributions to conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4477216	26180794	All authors	2	have contributed to this paper	have contributed to this paper	-	-	NO
4405343	25897514	ARK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405343	25897514	CKK	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405343	25897514	CKK	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405343	25897514	DSP	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405343	25897514	GSL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405343	25897514	HML	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405343	25897514	JHL	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4405343	25897514	SY	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4405343	25897514	THL	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405343	25897514	YHK	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405343	25897514	YJS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405343	25897514	YKK	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4405343	25897514	YS	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5622364	28970464	All authors	2	contributed equal efforts to this study	contributed equal efforts to this study	-	-	NO
6413467	30711519	A.V.	2	conducted the in vitro experiments	conducted the in vitro experiments	Performed the experiments	Investigation	YES
6413467	30711519	G.M.H.	2	wrote the paper with feedback from all authors	wrote the paper with feedback from all authors	Wrote the paper	Writing - Original Draft	YES
6413467	30711519	L.F.	2	wrote the paper with feedback from all authors	wrote the paper with feedback from all authors	Wrote the paper	Writing - Original Draft	YES
6413467	30711519	L.M.C.	2	contributed to the mirna mimics experiments	contributed to the mirna mimics experiments	Performed the experiments	Investigation	YES
6413467	30711519	M.A.M.	2	conducted the in vitro experiments	conducted the in vitro experiments	Performed the experiments	Investigation	YES
6413467	30711519	P.R.H.	2	wrote the paper with feedback from all authors	wrote the paper with feedback from all authors	Wrote the paper	Writing - Original Draft	YES
5732507	29248014	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5732507	29248014	DLJ	2	participated in study execution, coordination and assisted in editing and finalizing the manuscript and gave critical review	participated in study execution, coordination and assisted in editing and finalizing the manuscript and gave critical review	Performed the experiments|Wrote the paper	Investigation|Project administration|Writing - Review & Editing	YES
5732507	29248014	GS	2	participated in study execution, coordination and assisted in editing and finalizing the manuscript and gave critical review	participated in study execution, coordination and assisted in editing and finalizing the manuscript and gave critical review	Performed the experiments|Wrote the paper	Investigation|Project administration|Writing - Review & Editing	YES
5732507	29248014	KP	2	participated in study execution, coordination and assisted in editing and finalizing the manuscript and gave critical review	participated in study execution, coordination and assisted in editing and finalizing the manuscript and gave critical review	Performed the experiments|Wrote the paper	Investigation|Project administration|Writing - Review & Editing	YES
5732507	29248014	MLA	2	participated in study execution, coordination and assisted in editing and finalizing the manuscript and gave critical review	participated in study execution, coordination and assisted in editing and finalizing the manuscript and gave critical review	Performed the experiments|Wrote the paper	Investigation|Project administration|Writing - Review & Editing	YES
5732507	29248014	RC	2	participated in study execution, coordination and assisted in editing and finalizing the manuscript and gave critical review	participated in study execution, coordination and assisted in editing and finalizing the manuscript and gave critical review	Performed the experiments|Wrote the paper	Investigation|Project administration|Writing - Review & Editing	YES
5732507	29248014	SMW	2	participated in study execution, coordination and assisted in editing and finalizing the manuscript and gave critical review	participated in study execution, coordination and assisted in editing and finalizing the manuscript and gave critical review	Performed the experiments|Wrote the paper	Investigation|Project administration|Writing - Review & Editing	YES
5137333	27942383	Bertozzi Nicolo	2	data collections	data collections	Performed the experiments	Investigation	YES
5137333	27942383	Eugenio Grignaffini	2	data collections	data collections	Performed the experiments	Investigation	YES
5137333	27942383	Grieco Michele Pio	2	data collections	data collections	Performed the experiments	Investigation	YES
5137333	27942383	Raposio Edoardo	2	study design	study design	Conceived and designed the experiments	Methodology	YES
6161981	30079440	AB	2	devised the study, participated in its design and coordination, and drafted the manuscript	devised the study, participated in its design and coordination, and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
6161981	30079440	AD	2	participated in the interpretation of pharmacovigilance data	participated in the interpretation of pharmacovigilance data	Analyzed the data	Formal analysis	YES
6161981	30079440	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6161981	30079440	CC	2	participated in the collection of clinical data	participated in the collection of clinical data	Performed the experiments	Investigation	YES
6161981	30079440	CP	2	participated in the literature search and interpretation	participated in the literature search and interpretation	Analyzed the data	Formal analysis	YES
6161981	30079440	LA	2	participated in the study design, literature search, data collection and interpretation, and drafting of the manuscript	participated in the study design, literature search, data collection and interpretation, and drafting of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
6161981	30079440	MES	2	participated in the interpretation of pharmacovigilance data	participated in the interpretation of pharmacovigilance data	Analyzed the data	Formal analysis	YES
5529386	28798769	C-CT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Conceived of the study, edited the manuscript, and approved the final manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5529386	28798769	C-CT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Conceived of the study, edited the manuscript, and approved the final manuscript	Performed the experiments	Performed the experiments	Investigation	YES
5529386	28798769	C-CT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Conceived of the study, edited the manuscript, and approved the final manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
5529386	28798769	C-CT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Conceived of the study, edited the manuscript, and approved the final manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5529386	28798769	C-CT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Conceived of the study, edited the manuscript, and approved the final manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5529386	28798769	C-CT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Conceived of the study, edited the manuscript, and approved the final manuscript	Conceived of the study, edited the manuscript, and approved the final manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5529386	28798769	C-RS	PLoS5	Performed the experiments|Wrote the paper|Conceived of the study, edited the manuscript, and approved the final manuscript	Performed the experiments	Performed the experiments	Investigation	YES
5529386	28798769	C-RS	PLoS5	Performed the experiments|Wrote the paper|Conceived of the study, edited the manuscript, and approved the final manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5529386	28798769	C-RS	PLoS5	Performed the experiments|Wrote the paper|Conceived of the study, edited the manuscript, and approved the final manuscript	Conceived of the study, edited the manuscript, and approved the final manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5529386	28798769	H-TC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
5529386	28798769	H-TC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5529386	28798769	J-WL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
5529386	28798769	J-WL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5529386	28798769	P-CL	PLoS5	Performed the experiments|Wrote the paper|Conceived of the study, edited the manuscript, and approved the final manuscript	Performed the experiments	Performed the experiments	Investigation	YES
5529386	28798769	P-CL	PLoS5	Performed the experiments|Wrote the paper|Conceived of the study, edited the manuscript, and approved the final manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5529386	28798769	P-CL	PLoS5	Performed the experiments|Wrote the paper|Conceived of the study, edited the manuscript, and approved the final manuscript	Conceived of the study, edited the manuscript, and approved the final manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5529386	28798769	S-JL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
5529386	28798769	S-JL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5529386	28798769	W-LL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5529386	28798769	Y-CC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Conceived of the study, edited the manuscript, and approved the final manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5529386	28798769	Y-CC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Conceived of the study, edited the manuscript, and approved the final manuscript	Performed the experiments	Performed the experiments	Investigation	YES
5529386	28798769	Y-CC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Conceived of the study, edited the manuscript, and approved the final manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
5529386	28798769	Y-CC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Conceived of the study, edited the manuscript, and approved the final manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5529386	28798769	Y-CC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Conceived of the study, edited the manuscript, and approved the final manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5529386	28798769	Y-CC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Conceived of the study, edited the manuscript, and approved the final manuscript	Conceived of the study, edited the manuscript, and approved the final manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5529386	28798769	Y-HC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
5529386	28798769	Y-HC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5529386	28798769	Y-JW	PLoS5	Performed the experiments|Wrote the paper|Conceived of the study, edited the manuscript, and approved the final manuscript	Performed the experiments	Performed the experiments	Investigation	YES
5529386	28798769	Y-JW	PLoS5	Performed the experiments|Wrote the paper|Conceived of the study, edited the manuscript, and approved the final manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5529386	28798769	Y-JW	PLoS5	Performed the experiments|Wrote the paper|Conceived of the study, edited the manuscript, and approved the final manuscript	Conceived of the study, edited the manuscript, and approved the final manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5529386	28798769	Y-ZK	PLoS5	Contributed reagents/materials/analysis tools|Conceived of the study, edited the manuscript, and approved the final manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5529386	28798769	Y-ZK	PLoS5	Contributed reagents/materials/analysis tools|Conceived of the study, edited the manuscript, and approved the final manuscript	Conceived of the study, edited the manuscript, and approved the final manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
526184	15453914	AK	2	constructed multiple cdna libraries included in the unigene cdnas, performed over 18,000 pcr reactions, performed the library normalization by filter screening shown in figure 1 , the array hybridization reactions including that of fig 4 , and drafted protocols	constructed multiple cdna libraries included in the unigene cdnas, performed over 18,000 pcr reactions, performed the library normalization by filter screening shown in figure 1 , the array hybridization reactions including that of fig 4 , and drafted protocols	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Visualization|Writing - Original Draft	YES
526184	15453914	AR-H	2	provided hydroponically grown plant material and rnas for figure 4 and constructed a cdna library	provided hydroponically grown plant material and rnas for figure 4 and constructed a cdna library	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources|Visualization	YES
526184	15453914	CS	2	performed est analysis and clustering for the unigene set	performed est analysis and clustering for the unigene set	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
526184	15453914	DOG	2	performed 10,000 pcr reactions, printed arrays, and participated in clone rearraying	performed 10,000 pcr reactions, printed arrays, and participated in clone rearraying	Performed the experiments	Investigation	YES
526184	15453914	ER	2	coordinated est processing and informatics	coordinated est processing and informatics	-	Formal analysis|Project administration	YES
526184	15453914	ES	2	performed est analysis and clustering for the unigene set	performed est analysis and clustering for the unigene set	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
526184	15453914	GG	2	performed annotations of the 27,500 unigene set	performed annotations of the 27,500 unigene set	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
526184	15453914	GZ	2	accumulated the choice clone cdnas and performed the isoline hybridization analysis shown in figure 3	accumulated the choice clone cdnas and performed the isoline hybridization analysis shown in figure 3	Performed the experiments	Investigation|Visualization	YES
526184	15453914	JCP	2	provided hydroponically grown plant material and rnas for figure 4 and constructed a cdna library	provided hydroponically grown plant material and rnas for figure 4 and constructed a cdna library	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources|Visualization	YES
526184	15453914	JE	2	constructed multiple cdna libraries used in selecting the unigene set	constructed multiple cdna libraries used in selecting the unigene set	Performed the experiments	Investigation	YES
526184	15453914	JP	2	led or performed the 3 sequencing of the 27,500 unigene clones	led or performed the 3 sequencing of the 27,500 unigene clones	Performed the experiments	Investigation	YES
526184	15453914	LL	2	performed annotations of the 27,500 unigene set	performed annotations of the 27,500 unigene set	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
526184	15453914	LOV	2	led the unigene and microarray development, coordinated the project, and drafted the manuscript	led the unigene and microarray development, coordinated the project, and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Project administration|Writing - Original Draft	YES
526184	15453914	MS	2	contributed to informatics and sample tracking and gel analysis of pcr products	contributed to informatics and sample tracking and gel analysis of pcr products	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
526184	15453914	MVS	2	performed est cluster analysis for development of the unigene set and drafted sections of the paper	performed est cluster analysis for development of the unigene set and drafted sections of the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
526184	15453914	PC	2	constructed multiple cdna libraries	constructed multiple cdna libraries	Performed the experiments	Investigation	YES
526184	15453914	PS	2	led or performed the 3 sequencing of the 27,500 unigene clones	led or performed the 3 sequencing of the 27,500 unigene clones	Performed the experiments	Investigation	YES
526184	15453914	RP	2	contributed to protocol development, pcr production, and gel analysis	contributed to protocol development, pcr production, and gel analysis	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
526184	15453914	RS	2	led the informatics and sample tracking efforts for array printing, high throughput pcr, cdna clone reracking, printed arrays, developed and drafted protocols for analysis of array data|led the public est project for library construction and 5 sequencing	led the informatics and sample tracking efforts for array printing, high throughput pcr, cdna clone reracking, printed arrays, developed and drafted protocols for analysis of array data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
526184	15453914	RS	2	led the informatics and sample tracking efforts for array printing, high throughput pcr, cdna clone reracking, printed arrays, developed and drafted protocols for analysis of array data|led the public est project for library construction and 5 sequencing	led the public est project for library construction and 5 sequencing	Performed the experiments	Investigation	YES
526184	15453914	SJC	2	initiated the pcr and array hybridization protocols for the project and constructed several cdna libraries	initiated the pcr and array hybridization protocols for the project and constructed several cdna libraries	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
526184	15453914	VC	2	constructed multiple cdna libraries	constructed multiple cdna libraries	Performed the experiments	Investigation	YES
5622365	28970465	Alyson Brown	2	contributed to this research, and also to the write up of this manuscript	contributed to this research, and also to the write up of this manuscript	Wrote the paper	Writing - Original Draft	YES
5622365	28970465	Barbara McKenzie	2	researched and carried out this project, and wrote up the manuscript	researched and carried out this project, and wrote up the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4707296	26750379	All authors	2	approved the final version of the manuscript|had full access to all of the data in the study and take responsibility for the integrity of the data, as well as the accuracy of the data analysis	approved the final version of the manuscript	-	-	NO
4707296	26750379	All authors	2	approved the final version of the manuscript|had full access to all of the data in the study and take responsibility for the integrity of the data, as well as the accuracy of the data analysis	had full access to all of the data in the study and take responsibility for the integrity of the data, as well as the accuracy of the data analysis	Analyzed the data	Data curation|Formal analysis	YES
4707296	26750379	BD	2	performed the statistical analyses	performed the statistical analyses	Analyzed the data	Formal analysis	YES
4707296	26750379	BS	2	participated in the interpretation of results and contributed to the manuscripts review|were also involved in the design and implementation of the vespa2 survey	participated in the interpretation of results and contributed to the manuscripts review	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4707296	26750379	BS	2	participated in the interpretation of results and contributed to the manuscripts review|were also involved in the design and implementation of the vespa2 survey	were also involved in the design and implementation of the vespa2 survey	Conceived and designed the experiments|Performed the experiments	Investigation	YES
4707296	26750379	FL	2	were also involved in the design and implementation of the vespa2 survey	were also involved in the design and implementation of the vespa2 survey	Conceived and designed the experiments|Performed the experiments	Investigation	YES
4707296	26750379	FM	2	participated in the interpretation of results and contributed to the manuscripts review	participated in the interpretation of results and contributed to the manuscripts review	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4707296	26750379	MSM	2	participated in the data analysis and interpretation of results and wrote the first draft of the manuscript|participated in the interpretation of results and contributed to the manuscripts review|were also involved in the design and implementation of the vespa2 survey	participated in the data analysis and interpretation of results and wrote the first draft of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4707296	26750379	MSM	2	participated in the data analysis and interpretation of results and wrote the first draft of the manuscript|participated in the interpretation of results and contributed to the manuscripts review|were also involved in the design and implementation of the vespa2 survey	participated in the interpretation of results and contributed to the manuscripts review	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4707296	26750379	MSM	2	participated in the data analysis and interpretation of results and wrote the first draft of the manuscript|participated in the interpretation of results and contributed to the manuscripts review|were also involved in the design and implementation of the vespa2 survey	were also involved in the design and implementation of the vespa2 survey	Conceived and designed the experiments|Performed the experiments	Investigation	YES
4707296	26750379	NL	2	participated in the interpretation of results and contributed to the manuscripts review	participated in the interpretation of results and contributed to the manuscripts review	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4707296	26750379	RDS	2	were also involved in the design and implementation of the vespa2 survey	were also involved in the design and implementation of the vespa2 survey	Conceived and designed the experiments|Performed the experiments	Investigation	YES
4405344	25897749	BS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405344	25897749	HA	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405344	25897749	HY	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405344	25897749	IG	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405344	25897749	IG	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405344	25897749	LC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405344	25897749	PJD	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405344	25897749	ST	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405344	25897749	ST	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405344	25897749	ST	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405344	25897749	ST	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5153441	27994871	DP	2	analyzed and interpreted the results|revised the manuscript|approved the final version	analyzed and interpreted the results	Analyzed the data	Formal analysis	YES
5153441	27994871	DP	2	analyzed and interpreted the results|revised the manuscript|approved the final version	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5153441	27994871	DP	2	analyzed and interpreted the results|revised the manuscript|approved the final version	approved the final version	-	-	NO
5153441	27994871	GRJ	2	drafted the manuscript|approved the final version	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5153441	27994871	GRJ	2	drafted the manuscript|approved the final version	approved the final version	-	-	NO
5153441	27994871	MS	2	analyzed and interpreted the results|revised the manuscript|approved the final version	analyzed and interpreted the results	Analyzed the data	Formal analysis	YES
5153441	27994871	MS	2	analyzed and interpreted the results|revised the manuscript|approved the final version	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5153441	27994871	MS	2	analyzed and interpreted the results|revised the manuscript|approved the final version	approved the final version	-	-	NO
5153441	27994871	ND	2	revised the manuscript|approved the final version	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5153441	27994871	ND	2	revised the manuscript|approved the final version	approved the final version	-	-	NO
5153441	27994871	NH	2	revised the manuscript|approved the final version	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5153441	27994871	NH	2	revised the manuscript|approved the final version	approved the final version	-	-	NO
5771035	29338735	ART	2	conducted data analysis and assisted in data interpretation, reviewing, and revising the manuscript|have nothing to disclose	conducted data analysis and assisted in data interpretation, reviewing, and revising the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5771035	29338735	ART	2	conducted data analysis and assisted in data interpretation, reviewing, and revising the manuscript|have nothing to disclose	have nothing to disclose	-	-	NO
5771035	29338735	All	2	participants provided written informed consent	participants provided written informed consent	Wrote the paper	Writing - Original Draft	YES
5771035	29338735	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5771035	29338735	DSB	2	assisted with study conception, data interpretation and revising the original manuscript|have nothing to disclose	assisted with study conception, data interpretation and revising the original manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Review & Editing	YES
5771035	29338735	DSB	2	assisted with study conception, data interpretation and revising the original manuscript|have nothing to disclose	have nothing to disclose	-	-	NO
5771035	29338735	EFE	2	was responsible for revising manuscript and approving final version and overseeing data interpretation	was responsible for revising manuscript and approving final version and overseeing data interpretation	Analyzed the data|Wrote the paper	Formal analysis|Supervision|Writing - Review & Editing	YES
5771035	29338735	LAS	2	was primarily responsible for study design, acquisition of data, interpretation of data, and drafting manuscript|have nothing to disclose	was primarily responsible for study design, acquisition of data, interpretation of data, and drafting manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5771035	29338735	LAS	2	was primarily responsible for study design, acquisition of data, interpretation of data, and drafting manuscript|have nothing to disclose	have nothing to disclose	-	-	NO
5771035	29338735	MJM	2	assisted with study conception, data interpretation and revising the original manuscript	assisted with study conception, data interpretation and revising the original manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Review & Editing	YES
5529393	28798758	CC	2	did the plasmid constructions and statistical analysis	did the plasmid constructions and statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5529393	28798758	CZ	2	performed the tissue culture related experiments	performed the tissue culture related experiments	Performed the experiments	Investigation	YES
5529393	28798758	HR	2	did the plasmid constructions and statistical analysis	did the plasmid constructions and statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5529393	28798758	LZ	2	performed the tissue culture related experiments	performed the tissue culture related experiments	Performed the experiments	Investigation	YES
5529393	28798758	MX	2	performed the tissue culture related experiments	performed the tissue culture related experiments	Performed the experiments	Investigation	YES
5529393	28798758	QZ	2	conceived the project, designed experiments, and wrote the manuscript	conceived the project, designed experiments, and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
5529393	28798758	SY	2	did the plasmid constructions and statistical analysis	did the plasmid constructions and statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5529393	28798758	TY	2	performed the tissue culture related experiments	performed the tissue culture related experiments	Performed the experiments	Investigation	YES
5529393	28798758	WW	2	performed the tissue culture related experiments	performed the tissue culture related experiments	Performed the experiments	Investigation	YES
5529393	28798758	XT	2	performed the tissue culture related experiments	performed the tissue culture related experiments	Performed the experiments	Investigation	YES
6161983	29654479	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6161983	29654479	EH	2	helped spreading the survey and provided critical appraisal of the manuscript	helped spreading the survey and provided critical appraisal of the manuscript	Performed the experiments	Investigation	YES
6161983	29654479	IW	2	helped spreading the survey and provided critical appraisal of the manuscript	helped spreading the survey and provided critical appraisal of the manuscript	Performed the experiments	Investigation	YES
6161983	29654479	LS	2	helped spreading the survey and provided critical appraisal of the manuscript	helped spreading the survey and provided critical appraisal of the manuscript	Performed the experiments	Investigation	YES
6161983	29654479	MN	2	is the primary author and performed the survey, analyzing, writing and editing of the data	is the primary author and performed the survey, analyzing, writing and editing of the data	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
6161983	29654479	RH	2	helped spreading the survey and provided critical appraisal of the manuscript	helped spreading the survey and provided critical appraisal of the manuscript	Performed the experiments	Investigation	YES
6161983	29654479	RK	2	helped spreading the survey and provided critical appraisal of the manuscript	helped spreading the survey and provided critical appraisal of the manuscript	Performed the experiments	Investigation	YES
6161983	29654479	TE	2	helped spreading the survey and provided critical appraisal of the manuscript	helped spreading the survey and provided critical appraisal of the manuscript	Performed the experiments	Investigation	YES
5748535	28991203	Jeffrey Atkinson	2	wrote the first manuscript and dealt with revisions	wrote the first manuscript and dealt with revisions	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5748535	28991203	Petr Nachtigal	2	provided all the data and information and helped in the revisions of the manuscript	provided all the data and information and helped in the revisions of the manuscript	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Review & Editing	YES
5748535	28991203	Tomas Simunek	2	provided all the data and information and helped in the revisions of the manuscript	provided all the data and information and helped in the revisions of the manuscript	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Review & Editing	YES
4712323	26765347	W. All	2	authors provided critical input to the study design and conduct, and wrote and approved the final manuscript	authors provided critical input to the study design and conduct, and wrote and approved the final manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
4405345	25898322	AC	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405345	25898322	BG	PLoS5	Wrote the paper|Tephrochronology	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405345	25898322	BG	PLoS5	Wrote the paper|Tephrochronology	Tephrochronology	-	-	NO
4405345	25898322	BJ	PLoS5	Wrote the paper|Tephrochronology	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405345	25898322	BJ	PLoS5	Wrote the paper|Tephrochronology	Tephrochronology	-	-	NO
4405345	25898322	CL	PLoS5	Wrote the paper|Use-wear analysis	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405345	25898322	CL	PLoS5	Wrote the paper|Use-wear analysis	Use-wear analysis	-	-	NO
4405345	25898322	DA	PLoS5	Wrote the paper|Conceived and designed the article|Lithic industry analysis	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405345	25898322	DA	PLoS5	Wrote the paper|Conceived and designed the article|Lithic industry analysis	Conceived and designed the article	Conceived and designed the experiments	Conceptualization	YES
4405345	25898322	DA	PLoS5	Wrote the paper|Conceived and designed the article|Lithic industry analysis	Lithic industry analysis	-	-	NO
4405345	25898322	DM	PLoS5	Wrote the paper|Pollen analysis	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405345	25898322	DM	PLoS5	Wrote the paper|Pollen analysis	Pollen analysis	-	-	NO
4405345	25898322	FM	PLoS5	Wrote the paper|Fauna	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405345	25898322	FM	PLoS5	Wrote the paper|Fauna	Fauna	-	-	NO
4405345	25898322	MRP	PLoS5	Wrote the paper|Fauna	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405345	25898322	MRP	PLoS5	Wrote the paper|Fauna	Fauna	-	-	NO
4405345	25898322	RP	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405345	25898322	RR	PLoS5	Wrote the paper|Conceived and designed the article|Lithic industry analysis	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405345	25898322	RR	PLoS5	Wrote the paper|Conceived and designed the article|Lithic industry analysis	Conceived and designed the article	Conceived and designed the experiments	Conceptualization	YES
4405345	25898322	RR	PLoS5	Wrote the paper|Conceived and designed the article|Lithic industry analysis	Lithic industry analysis	-	-	NO
4405345	25898322	S. Madonna	PLoS5	Wrote the paper|Geology	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405345	25898322	S. Madonna	PLoS5	Wrote the paper|Geology	Geology	-	-	NO
4405345	25898322	S. Milli	PLoS5	Wrote the paper|Geology	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405345	25898322	S. Milli	PLoS5	Wrote the paper|Geology	Geology	-	-	NO
4405345	25898322	VM	PLoS5	Wrote the paper|Lithic industry analysis	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405345	25898322	VM	PLoS5	Wrote the paper|Lithic industry analysis	Lithic industry analysis	-	-	NO
526187	15473903	AE	2	developed rh markers and constructed the rh map|conceived the research, and contributed to planning analyses and evaluating results	developed rh markers and constructed the rh map	Performed the experiments	Investigation	YES
526187	15473903	AE	2	developed rh markers and constructed the rh map|conceived the research, and contributed to planning analyses and evaluating results	conceived the research, and contributed to planning analyses and evaluating results	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
526187	15473903	AT	2	developed linkage markers	developed linkage markers	-	-	NO
526187	15473903	GLB	2	coordinated linkage map data collection|curates the marc linkage data and linkage maps	coordinated linkage map data collection	Performed the experiments	Investigation|Project administration	YES
526187	15473903	GLB	2	coordinated linkage map data collection|curates the marc linkage data and linkage maps	curates the marc linkage data and linkage maps	Analyzed the data	Data curation	YES
526187	15473903	HT	2	developed linkage markers	developed linkage markers	-	-	NO
526187	15473903	JWK	2	conceived the research, and contributed to planning analyses and evaluating results	conceived the research, and contributed to planning analyses and evaluating results	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
526187	15473903	MG	2	developed rh markers and constructed the rh map	developed rh markers and constructed the rh map	Performed the experiments	Investigation	YES
526187	15473903	NI	2	developed linkage markers	developed linkage markers	-	-	NO
526187	15473903	RTS	2	assisted with evaluation of the integrated map	assisted with evaluation of the integrated map	-	-	NO
526187	15473903	TPLS	2	assisted with evaluation of the integrated map	assisted with evaluation of the integrated map	-	-	NO
526187	15473903	WMS	2	developed perl scripts for automated analyses, conducted analyses to match markers from linkage and rh data sets, constructed the linkage and integrated maps, and drafted the manuscript	developed perl scripts for automated analyses, conducted analyses to match markers from linkage and rh data sets, constructed the linkage and integrated maps, and drafted the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Software|Writing - Original Draft	YES
526187	15473903	YS	2	coordinated linkage map data collection	coordinated linkage map data collection	Performed the experiments	Investigation|Project administration	YES
6442001	30745170	All authors	1	Critical revision of the manuscript for important intellectual content	Critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5784661	29368619	AA	2	assisted in scientific inputs and draft editing	assisted in scientific inputs and draft editing	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5784661	29368619	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5784661	29368619	JO	2	was also a great support in developing the document and editing	was also a great support in developing the document and editing	Wrote the paper	Writing - Review & Editing	YES
5784661	29368619	Kate Drezner	2	for editing the paper	for editing the paper	Wrote the paper	Writing - Review & Editing	YES
5784661	29368619	MK	2	was instrumental in draft editing	was instrumental in draft editing	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5784661	29368619	SD	2	conceived the idea of the analysis, did the data analysis as well wrote the majority of the text	conceived the idea of the analysis, did the data analysis as well wrote the majority of the text	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
5784661	29368619	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
6161984	29511876	AA	2	undertook the mathematical analyses	undertook the mathematical analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6161984	29511876	AV	2	were involved in the design and planning of the original actigraphy studies with inpatients	were involved in the design and planning of the original actigraphy studies with inpatients	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6161984	29511876	All	2	individuals consented to the publication of their data	individuals consented to the publication of their data	-	-	NO
6161984	29511876	All authors	2	critically reviewed the drafts|read and approved the final manuscript	critically reviewed the drafts	Wrote the paper	Writing - Original Draft	YES
6161984	29511876	All authors	2	critically reviewed the drafts|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6161984	29511876	Erlend Fasmer	2	for making programs to extract actigraphy data	for making programs to extract actigraphy data	Performed the experiments	Investigation	YES
6161984	29511876	GM	2	were involved in the design and planning of the original actigraphy studies with inpatients|identified the hypotheses for the current study	were involved in the design and planning of the original actigraphy studies with inpatients	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6161984	29511876	GM	2	were involved in the design and planning of the original actigraphy studies with inpatients|identified the hypotheses for the current study	identified the hypotheses for the current study	Performed the experiments	Investigation	YES
6161984	29511876	JS	2	identified the hypotheses for the current study|wrote the preliminary draft of the manuscript	identified the hypotheses for the current study	Performed the experiments	Investigation	YES
6161984	29511876	JS	2	identified the hypotheses for the current study|wrote the preliminary draft of the manuscript	wrote the preliminary draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
6161984	29511876	KKG	2	were involved in the design and planning of the original actigraphy studies with inpatients|identified the hypotheses for the current study|undertook the mathematical analyses|wrote the preliminary draft of the manuscript	were involved in the design and planning of the original actigraphy studies with inpatients	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6161984	29511876	KKG	2	were involved in the design and planning of the original actigraphy studies with inpatients|identified the hypotheses for the current study|undertook the mathematical analyses|wrote the preliminary draft of the manuscript	identified the hypotheses for the current study	Performed the experiments	Investigation	YES
6161984	29511876	KKG	2	were involved in the design and planning of the original actigraphy studies with inpatients|identified the hypotheses for the current study|undertook the mathematical analyses|wrote the preliminary draft of the manuscript	undertook the mathematical analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6161984	29511876	KKG	2	were involved in the design and planning of the original actigraphy studies with inpatients|identified the hypotheses for the current study|undertook the mathematical analyses|wrote the preliminary draft of the manuscript	wrote the preliminary draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
6161984	29511876	OBF	2	were involved in the design and planning of the original actigraphy studies with inpatients|undertook the mathematical analyses	were involved in the design and planning of the original actigraphy studies with inpatients	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6161984	29511876	OBF	2	were involved in the design and planning of the original actigraphy studies with inpatients|undertook the mathematical analyses	undertook the mathematical analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4716565	26782169	All authors	2	contributed to the interpretation of the findings|contributed to the subsequent drafts and approved the final version	contributed to the interpretation of the findings	Analyzed the data	Formal analysis	YES
4716565	26782169	All authors	2	contributed to the interpretation of the findings|contributed to the subsequent drafts and approved the final version	contributed to the subsequent drafts and approved the final version	Wrote the paper	Writing - Original Draft	YES
4716565	26782169	DOB	2	conceived the study|wrote the first draft of the paper	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4716565	26782169	DOB	2	conceived the study|wrote the first draft of the paper	wrote the first draft of the paper	Wrote the paper	Writing - Original Draft	YES
4716565	26782169	JG	2	collected and analyzed the data	collected and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4716565	26782169	NF	2	conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4716565	26782169	TS	2	collected and analyzed the data	collected and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5748536	29019923	AAE	2	performed the statistical analysis, wrote and edited the paper	performed the statistical analysis, wrote and edited the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5748536	29019923	AS	2	wrote and edited the paper	wrote and edited the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5748536	29019923	ASB	2	planned and conducted the study analysed the results and wrote the paper|performed the statistical analysis, wrote and edited the paper	planned and conducted the study analysed the results and wrote the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
5748536	29019923	ASB	2	planned and conducted the study analysed the results and wrote the paper|performed the statistical analysis, wrote and edited the paper	performed the statistical analysis, wrote and edited the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5748536	29019923	DKB	2	collected the data, entered the data into spss and anaylsed the data	collected the data, entered the data into spss and anaylsed the data	Performed the experiments	Investigation	YES
5748536	29019923	SQJ	2	analysed the results, wrote and edited the paper	analysed the results, wrote and edited the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5748536	29019923	YGT	2	collected the data, entered the data into spss and anaylsed the data|wrote and edited the paper	collected the data, entered the data into spss and anaylsed the data	Performed the experiments	Investigation	YES
5748536	29019923	YGT	2	collected the data, entered the data into spss and anaylsed the data|wrote and edited the paper	wrote and edited the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5748536	29019923	all the authors	2	equally contributed in planning the study, analysed the results, wrote and edited the paper	equally contributed in planning the study, analysed the results, wrote and edited the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5529406	28798756	AS	2	did the analytic for lc-ms assays	did the analytic for lc-ms assays	Performed the experiments	Investigation	YES
5529406	28798756	DR	2	designed the study|carried out plant growth promoting and biocontrol assays	designed the study	Conceived and designed the experiments	Methodology	YES
5529406	28798756	DR	2	designed the study|carried out plant growth promoting and biocontrol assays	carried out plant growth promoting and biocontrol assays	Performed the experiments	Investigation	YES
5529406	28798756	GB	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5529406	28798756	LC-MS	2	gc-ms assays and analyzed the gc-ms data	gc-ms assays and analyzed the gc-ms data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5529406	28798756	MS	2	carried out plant growth promoting and biocontrol assays	carried out plant growth promoting and biocontrol assays	Performed the experiments	Investigation	YES
5529406	28798756	R. All	2	authors read and approved the final manuscript	authors read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5529406	28798756	TC	2	contributed to the vocs-related parts of the final manuscript	contributed to the vocs-related parts of the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5529406	28798756	UR	2	carried out the in vitro	carried out the in vitro	Performed the experiments	Investigation	YES
526188	15488154	HN	2	participated in the sequence alignment and performed the phylogenetic analysis	participated in the sequence alignment and performed the phylogenetic analysis	Performed the experiments	Investigation	YES
526188	15488154	IU	2	participated in the design of the study	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
526188	15488154	YK	2	conceived of the study and drafted the manuscript|participated in its design and coordination	conceived of the study and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
526188	15488154	YK	2	conceived of the study and drafted the manuscript|participated in its design and coordination	participated in its design and coordination	Conceived and designed the experiments	Project administration	YES
526188	15488154	YS	2	participated in its design and coordination	participated in its design and coordination	Conceived and designed the experiments	Project administration	YES
5173312	28018587	Abdelfattah A. Elkholy	7	data collections	data collections	Performed the experiments	Investigation	YES
5173312	28018587	Akram E. El-Sadek	7	data collections, data analysis	data collections, data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5173312	28018587	Amal E. Mohammed	7	study design	study design	Conceived and designed the experiments	Methodology	YES
5173312	28018587	Dalia M. Mahmoud	7	data collections	data collections	Performed the experiments	Investigation	YES
5173312	28018587	Eman G. Behiry	7	data collections, data analysis, writing	data collections, data analysis, writing	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation	YES
5173312	28018587	Waleed E. Abdulghany	7	data collections, data analysis	data collections, data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4405347	25897861	CYH	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405347	25897861	CYH	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405347	25897861	CYH	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405347	25897861	CYL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405347	25897861	CYL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405347	25897861	CYL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405347	25897861	CYL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405347	25897861	CYL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405347	25897861	JCH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405347	25897861	JCH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405347	25897861	JCH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405347	25897861	JCH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405347	25897861	JCH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405347	25897861	YHKY	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405347	25897861	YHKY	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3575634	23431263	K. Zhang	2	contributed equally to this work	contributed equally to this work	-	-	NO
3575634	23431263	S. Zhang	2	contributed equally to this work	contributed equally to this work	-	-	NO
3575634	23431263	Y. Wang	2	contributed equally to this work	contributed equally to this work	-	-	NO
5748537	29035338	Brian Isetts	2	is the sole investigator and author of this manuscript, and has been responsible for all phases of this study	is the sole investigator and author of this manuscript, and has been responsible for all phases of this study	-	-	NO
6444124	30857944	AMD	PLoS52	conceived and designed experiments|analyzed the data|wrote the manuscript	conceived and designed experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6444124	30857944	AMD	PLoS52	conceived and designed experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
6444124	30857944	AMD	PLoS52	conceived and designed experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6444124	30857944	APD	PLoS52	provided specimens	provided specimens	Performed the experiments	Investigation	YES
6444124	30857944	All authors	PLoS52	participated in the editorial process and approved the manuscript	participated in the editorial process and approved the manuscript	Wrote the paper	Writing - Review & Editing	YES
6444124	30857944	BDK	PLoS52	provided specimens	provided specimens	Performed the experiments	Investigation	YES
6444124	30857944	BP	PLoS52	performed experiments	performed experiments	Performed the experiments	Investigation	YES
6444124	30857944	DEE	PLoS52	conceived and designed experiments|analyzed the data	conceived and designed experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6444124	30857944	DEE	PLoS52	conceived and designed experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
6444124	30857944	HAT	PLoS52	performed experiments|analyzed the data|wrote the manuscript	performed experiments	Performed the experiments	Investigation	YES
6444124	30857944	HAT	PLoS52	performed experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
6444124	30857944	HAT	PLoS52	performed experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6444124	30857944	JS	PLoS52	performed experiments	performed experiments	Performed the experiments	Investigation	YES
6444124	30857944	KKP	PLoS52	provided specimens	provided specimens	Performed the experiments	Investigation	YES
6444124	30857944	MJD	PLoS52	performed experiments	performed experiments	Performed the experiments	Investigation	YES
6444124	30857944	NN	PLoS52	performed experiments|analyzed the data	performed experiments	Performed the experiments	Investigation	YES
6444124	30857944	NN	PLoS52	performed experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
6444124	30857944	RSB	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
6444124	30857944	SAD	PLoS52	conceived and designed experiments|analyzed the data|wrote the manuscript	conceived and designed experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6444124	30857944	SAD	PLoS52	conceived and designed experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
6444124	30857944	SAD	PLoS52	conceived and designed experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6444124	30857944	SSW	PLoS52	provided specimens	provided specimens	Performed the experiments	Investigation	YES
6444124	30857944	UKN	PLoS52	performed experiments|wrote the manuscript	performed experiments	Performed the experiments	Investigation	YES
6444124	30857944	UKN	PLoS52	performed experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6444124	30857944	UNK	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
6161985	30097737	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6161985	30097737	HKK	2	participated in the conceptualization, planning, analysis and reporting of the study	participated in the conceptualization, planning, analysis and reporting of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6161985	30097737	MT	2	is the primary investigator for the mclean-harvard first-episode project and participated in the study reporting	is the primary investigator for the mclean-harvard first-episode project and participated in the study reporting	-	-	NO
6161985	30097737	PS	2	participated in the conceptualization of the study, planning, analysis and reporting of study findings	participated in the conceptualization of the study, planning, analysis and reporting of study findings	Conceived and designed the experiments	Conceptualization|Methodology	YES
6161985	30097737	RJB	2	participated in the planning and reporting of the study	participated in the planning and reporting of the study	Conceived and designed the experiments	Methodology	YES
5784710	29370816	All	2	listed authors have contributed all the time in the design of the study and collection, analysis, and interpretation of data and in writing this manuscript	listed authors have contributed all the time in the design of the study and collection, analysis, and interpretation of data and in writing this manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
5784710	29370816	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5784710	29370816	IDI	2	mulago hospital in uganda for assistance in data collection and analysis	mulago hospital in uganda for assistance in data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5784710	29370816	Rosalind Parkes-Ratanshi	2	for assistance in preparation of this manuscript	for assistance in preparation of this manuscript	Wrote the paper	Writing - Original Draft	YES
5784710	29370816	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
4718968	26787516	All authors	2	reviewed and approved the manuscript for submission	reviewed and approved the manuscript for submission	Wrote the paper	Writing - Review & Editing	YES
4718968	26787516	EE	2	commented and edited drafts of the manuscript	commented and edited drafts of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4718968	26787516	IA	2	conceptualized the paper|conducted data analyses|commented and edited drafts of the manuscript	conceptualized the paper	Conceived and designed the experiments	Conceptualization	YES
4718968	26787516	IA	2	conceptualized the paper|conducted data analyses|commented and edited drafts of the manuscript	conducted data analyses	Analyzed the data	Formal analysis	YES
4718968	26787516	IA	2	conceptualized the paper|conducted data analyses|commented and edited drafts of the manuscript	commented and edited drafts of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4718968	26787516	JE	2	conceptualized the paper|drafted the manuscript	conceptualized the paper	Conceived and designed the experiments	Conceptualization	YES
4718968	26787516	JE	2	conceptualized the paper|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4718968	26787516	JG	2	conceptualized the paper|drafted the manuscript	conceptualized the paper	Conceived and designed the experiments	Conceptualization	YES
4718968	26787516	JG	2	conceptualized the paper|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4718968	26787516	KC	2	conceptualized the paper|drafted the manuscript	conceptualized the paper	Conceived and designed the experiments	Conceptualization	YES
4718968	26787516	KC	2	conceptualized the paper|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4718968	26787516	PW	2	conducted data analyses	conducted data analyses	Analyzed the data	Formal analysis	YES
4718968	26787516	SG	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5529415	28798755	AP	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5529415	28798755	DD	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5529415	28798755	IN	PLoS52	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5529415	28798755	KA	PLoS52	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5529415	28798755	LC	PLoS52	designed the study|wrote the paper	designed the study	Conceived and designed the experiments	Methodology	YES
5529415	28798755	LC	PLoS52	designed the study|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5529415	28798755	LCL	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5529415	28798755	MB	PLoS52	performed bioinformatics analysis	performed bioinformatics analysis	Performed the experiments	Formal analysis|Investigation	YES
5529415	28798755	MBH	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5529415	28798755	MG	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5529415	28798755	NK	PLoS52	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5529415	28798755	PN	PLoS52	designed the study|performed the experiments|performed bioinformatics analysis|wrote the paper	designed the study	Conceived and designed the experiments	Methodology	YES
5529415	28798755	PN	PLoS52	designed the study|performed the experiments|performed bioinformatics analysis|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5529415	28798755	PN	PLoS52	designed the study|performed the experiments|performed bioinformatics analysis|wrote the paper	performed bioinformatics analysis	Performed the experiments	Formal analysis|Investigation	YES
5529415	28798755	PN	PLoS52	designed the study|performed the experiments|performed bioinformatics analysis|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5529415	28798755	PO	PLoS52	performed bioinformatics analysis	performed bioinformatics analysis	Performed the experiments	Formal analysis|Investigation	YES
5529415	28798755	TH	PLoS52	designed the study|wrote the paper	designed the study	Conceived and designed the experiments	Methodology	YES
5529415	28798755	TH	PLoS52	designed the study|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5529415	28798755	WA	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5529415	28798755	YV	PLoS52	designed the study|wrote the paper	designed the study	Conceived and designed the experiments	Methodology	YES
5529415	28798755	YV	PLoS52	designed the study|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
526275	15473908	FML	2	implements the software and refinements the system	implements the software and refinements the system	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
526275	15473908	HDH	2	conceives of the study and drafted the manuscripts	conceives of the study and drafted the manuscripts	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
526275	15473908	JTH	2	participates the design and coordination	participates the design and coordination	Conceived and designed the experiments	Project administration	YES
526275	15473908	YCC	2	participates the design and coordination	participates the design and coordination	Conceived and designed the experiments	Project administration	YES
5173315	28018588	Anan Xu	2	acquired data and revised critically the manuscript	acquired data and revised critically the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5173315	28018588	Anhua Huang	2	contributed to the conception and design of the study, or acquisition of data	contributed to the conception and design of the study, or acquisition of data	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceptualization|Investigation|Methodology|Resources	YES
5173315	28018588	Chuanqi He	2	acquired data and revised critically the manuscript	acquired data and revised critically the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5173315	28018588	Gang Zhao	2	contributed to the conception and design of the study, or acquisition of data	contributed to the conception and design of the study, or acquisition of data	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceptualization|Investigation|Methodology|Resources	YES
5173315	28018588	Hai Hu	2	drafted the article and revised it critically for important intellectual content	drafted the article and revised it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5173315	28018588	Haidong Li	2	acquired data and revised critically the manuscript	acquired data and revised critically the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5173315	28018588	Jingli Cai	2	acquired data and revised critically the manuscript	acquired data and revised critically the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5173315	28018588	Kai Zhang	2	contributed to the conception and design of the study, or acquisition of data	contributed to the conception and design of the study, or acquisition of data	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceptualization|Investigation|Methodology|Resources	YES
5173315	28018588	Kan Ding	2	acquired data and revised critically the manuscript	acquired data and revised critically the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5173315	28018588	Ruiqi Lu	2	acquired data and revised critically the manuscript	acquired data and revised critically the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5173315	28018588	Zhaoyan Jiang	2	contributed to the conception and design of the study, or acquisition of data	contributed to the conception and design of the study, or acquisition of data	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceptualization|Investigation|Methodology|Resources	YES
5748538	29035337	All authors	2	executed the study and analyzed the results	executed the study and analyzed the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5748538	29035337	Harshali K. Patel	2	designed the survey	designed the survey	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5748538	29035337	Sujit S. Sansgiry	2	provided revisions/comments	provided revisions/comments	Wrote the paper	Writing - Review & Editing	YES
4405350	25897858	AJM-R	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Drafted the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405350	25897858	AJM-R	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Drafted the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4405350	25897858	AJM-R	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Drafted the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4405350	25897858	AJM-R	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Drafted the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405350	25897858	AJM-R	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Drafted the manuscript	Drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4405350	25897858	FL	PLoS5	Analyzed the fluorescence quenching data	Analyzed the fluorescence quenching data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4405350	25897858	JJF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405350	25897858	JJF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405350	25897858	JJF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405350	25897858	JJF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405350	25897858	JMFB	PLoS5	Conducted the mussel foot repulsion tests	Conducted the mussel foot repulsion tests	Performed the experiments	Investigation	YES
4405350	25897858	MN	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405350	25897858	VSM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4733160	26015387	AEG	2	assisted in formulating the analyses and drafting the manuscript	assisted in formulating the analyses and drafting the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
4733160	26015387	BRB	2	drafted the manuscript|formulated and performed the statistical analyses	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4733160	26015387	BRB	2	drafted the manuscript|formulated and performed the statistical analyses	formulated and performed the statistical analyses	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
4733160	26015387	FJ	2	formulated and performed the statistical analyses|assisted in formulating the analyses and drafting the manuscript	formulated and performed the statistical analyses	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
4733160	26015387	FJ	2	formulated and performed the statistical analyses|assisted in formulating the analyses and drafting the manuscript	assisted in formulating the analyses and drafting the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
4733160	26015387	GPP	2	assisted in formulating the analyses and drafting the manuscript	assisted in formulating the analyses and drafting the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
4733160	26015387	IZ	2	assisted in formulating the analyses and drafting the manuscript	assisted in formulating the analyses and drafting the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
4733160	26015387	LM	2	assisted in formulating the analyses and drafting the manuscript	assisted in formulating the analyses and drafting the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
6161986	29492700	AB	2	devised the study, participated in its design and coordination, and drafted the manuscript	devised the study, participated in its design and coordination, and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
6161986	29492700	AL	2	performed the assessment of thyroid function and participated in data interpretation and drafting of the manuscript	performed the assessment of thyroid function and participated in data interpretation and drafting of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6161986	29492700	AP	2	performed the assessment of renal function and participated in data interpretation and drafting of the manuscript	performed the assessment of renal function and participated in data interpretation and drafting of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6161986	29492700	All	2	patients signed an informed consent for publication of anonymous and aggregate data derived from their medical records|patients signed an informed consent for use of anonymous and aggregate data derived from their medical records	patients signed an informed consent for publication of anonymous and aggregate data derived from their medical records	-	-	NO
6161986	29492700	All	2	patients signed an informed consent for publication of anonymous and aggregate data derived from their medical records|patients signed an informed consent for use of anonymous and aggregate data derived from their medical records	patients signed an informed consent for use of anonymous and aggregate data derived from their medical records	-	-	NO
6161986	29492700	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6161986	29492700	CC	2	participated in the study design, literature search, and data collection and interpretation	participated in the study design, literature search, and data collection and interpretation	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
6161986	29492700	CP	2	participated in the study design, performed statistical analysis, and participated in data interpretation	participated in the study design, performed statistical analysis, and participated in data interpretation	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
6161986	29492700	DP	2	participated in the study design, performed statistical analysis, and participated in data interpretation|performed the assessment of renal function and participated in data interpretation and drafting of the manuscript	participated in the study design, performed statistical analysis, and participated in data interpretation	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
6161986	29492700	DP	2	participated in the study design, performed statistical analysis, and participated in data interpretation|performed the assessment of renal function and participated in data interpretation and drafting of the manuscript	performed the assessment of renal function and participated in data interpretation and drafting of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6161986	29492700	FV	2	performed the assessment of thyroid function and participated in data interpretation and drafting of the manuscript	performed the assessment of thyroid function and participated in data interpretation and drafting of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6161986	29492700	GB	2	participated in data collection and interpretation	participated in data collection and interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6161986	29492700	LA	2	participated in data collection and interpretation	participated in data collection and interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6161986	29492700	RA	2	participated in the study design, literature search, and data collection and interpretation	participated in the study design, literature search, and data collection and interpretation	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
6161986	29492700	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5176126	28018589	Javier Ramos-Jimenez	1	Lozano, study design, analysis and interpretation of the data	Lozano, study design, analysis and interpretation of the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
526369	15479470	CD	2	coordinated the study and wrote the larger part of the manuscript	coordinated the study and wrote the larger part of the manuscript	Wrote the paper	Project administration|Writing - Original Draft	YES
526369	15479470	JP	2	generated the hmm-derived alignments, constructed the epk phylogenetic trees and contributed significantly to their description in the text	generated the hmm-derived alignments, constructed the epk phylogenetic trees and contributed significantly to their description in the text	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
526369	15479470	PKs	2	compiled expression data and performed the in silico and in vitro analyses of the fikk family	compiled expression data and performed the in silico and in vitro analyses of the fikk family	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
526369	15479470	PW	2	performed most of the database searches for epk-related sequences and constructed the fikk phylogenetic tree	performed most of the database searches for epk-related sequences and constructed the fikk phylogenetic tree	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5532426	28804490	CP	2	developed the conceptual framework and drafted the manuscript	developed the conceptual framework and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5532426	28804490	EN	2	assisted in revising the manuscript	assisted in revising the manuscript	Wrote the paper	Writing - Review & Editing	YES
5532426	28804490	JW	2	assisted in revising the manuscript	assisted in revising the manuscript	Wrote the paper	Writing - Review & Editing	YES
5532426	28804490	KB	2	developed the conceptual framework and drafted the manuscript	developed the conceptual framework and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5532426	28804490	MY	2	assisted in reviewing existing in-season nutrient management tools	assisted in reviewing existing in-season nutrient management tools	-	-	NO
5748539	29048348	Christine Catney	2	provided additional feedback throughout the study	provided additional feedback throughout the study	-	-	NO
5748539	29048348	Community Pharmacy Residency	2	research project	research project	-	-	NO
5748539	29048348	Stevie Veach	2	provided additional feedback throughout the study	provided additional feedback throughout the study	-	-	NO
5785880	29370820	AOW	2	conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5785880	29370820	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5785880	29370820	EK	2	conceived the study|drafted the manuscript and all authors critically appraised and reviewed the manuscript submitted for publication	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5785880	29370820	EK	2	conceived the study|drafted the manuscript and all authors critically appraised and reviewed the manuscript submitted for publication	drafted the manuscript and all authors critically appraised and reviewed the manuscript submitted for publication	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5785880	29370820	GA	2	conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5785880	29370820	JB	2	conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5785880	29370820	JC	2	conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5785880	29370820	JN	2	conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5785880	29370820	MR	2	conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5785880	29370820	SK	2	conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5785880	29370820	SS	2	conceived the study|analyzed and interpreted the data|drafted the manuscript and all authors critically appraised and reviewed the manuscript submitted for publication	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5785880	29370820	SS	2	conceived the study|analyzed and interpreted the data|drafted the manuscript and all authors critically appraised and reviewed the manuscript submitted for publication	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5785880	29370820	SS	2	conceived the study|analyzed and interpreted the data|drafted the manuscript and all authors critically appraised and reviewed the manuscript submitted for publication	drafted the manuscript and all authors critically appraised and reviewed the manuscript submitted for publication	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4733944	26829360	AC	PLoS52	analyzed the data|wrote, reviewed and edited the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
4733944	26829360	AC	PLoS52	analyzed the data|wrote, reviewed and edited the manuscript	wrote, reviewed and edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4733944	26829360	HC	PLoS52	was responsible for the study design|analyzed the data|wrote, reviewed and edited the manuscript	was responsible for the study design	Conceived and designed the experiments	Methodology	YES
4733944	26829360	HC	PLoS52	was responsible for the study design|analyzed the data|wrote, reviewed and edited the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
4733944	26829360	HC	PLoS52	was responsible for the study design|analyzed the data|wrote, reviewed and edited the manuscript	wrote, reviewed and edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4733944	26829360	HS	PLoS52	collected the data and were responsible for laboratory methods and subject recruitment	collected the data and were responsible for laboratory methods and subject recruitment	Performed the experiments	Investigation	YES
4733944	26829360	MT	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
4733944	26829360	SC	PLoS52	collected the data and were responsible for laboratory methods and subject recruitment|wrote, reviewed and edited the manuscript	collected the data and were responsible for laboratory methods and subject recruitment	Performed the experiments	Investigation	YES
4733944	26829360	SC	PLoS52	collected the data and were responsible for laboratory methods and subject recruitment|wrote, reviewed and edited the manuscript	wrote, reviewed and edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4733944	26829360	WL	PLoS52	collected the data and were responsible for laboratory methods and subject recruitment	collected the data and were responsible for laboratory methods and subject recruitment	Performed the experiments	Investigation	YES
4733944	26829360	YS	PLoS52	collected the data and were responsible for laboratory methods and subject recruitment	collected the data and were responsible for laboratory methods and subject recruitment	Performed the experiments	Investigation	YES
5187602	28050248	All authors	5	have contributed equally to all aspects of this study (design	have contributed equally to all aspects of this study (design	Conceived and designed the experiments	Methodology	YES
4405356	25898372	DX	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405356	25898372	DX	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405356	25898372	HL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405356	25898372	HL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4405356	25898372	HL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4405356	25898372	HX	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405356	25898372	HX	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405356	25898372	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405356	25898372	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405356	25898372	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405356	25898372	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405356	25898372	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405356	25898372	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405356	25898372	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4405356	25898372	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4405356	25898372	TL	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405356	25898372	TL	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405356	25898372	WQ	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405356	25898372	ZG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405356	25898372	ZG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405356	25898372	ZG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405356	25898372	ZG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405356	25898372	ZG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5748540	29065508	The authors	2	contributed jointly to the research and writing of this manuscript	contributed jointly to the research and writing of this manuscript	Wrote the paper	Writing - Original Draft	YES
5532442	28804493	KF	2	performed the simulations	performed the simulations	Performed the experiments	Formal analysis|Investigation	YES
5532442	28804493	The authors	2	were equal contributors to the design of simulations, analysis of results, and drafting of the paper	were equal contributors to the design of simulations, analysis of results, and drafting of the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4477439	26180800	Qinghua Liu	2	contributed equally to the work	contributed equally to the work	-	-	NO
4477439	26180800	Xueying Wang	2	contributed equally to the work	contributed equally to the work	-	-	NO
6161987	29968068	AH	2	oversaw data collection|oversaw and conducted the inter-rater reliability analyses	oversaw data collection	Performed the experiments	Investigation|Supervision	YES
6161987	29968068	AH	2	oversaw data collection|oversaw and conducted the inter-rater reliability analyses	oversaw and conducted the inter-rater reliability analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Supervision	YES
6161987	29968068	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6161987	29968068	CM	2	oversaw data collection|complied and analyzed the data	oversaw data collection	Performed the experiments	Investigation|Supervision	YES
6161987	29968068	CM	2	oversaw data collection|complied and analyzed the data	complied and analyzed the data	Analyzed the data	Formal analysis	YES
6161987	29968068	DI	2	designed and piloted the task	designed and piloted the task	Conceived and designed the experiments	-	YES
6161987	29968068	JG	2	designed and piloted the task|oversaw data collection|complied and analyzed the data|oversaw manuscript writing with substantial contributions and feedback from all authors	designed and piloted the task	Conceived and designed the experiments	-	YES
6161987	29968068	JG	2	designed and piloted the task|oversaw data collection|complied and analyzed the data|oversaw manuscript writing with substantial contributions and feedback from all authors	oversaw data collection	Performed the experiments	Investigation|Supervision	YES
6161987	29968068	JG	2	designed and piloted the task|oversaw data collection|complied and analyzed the data|oversaw manuscript writing with substantial contributions and feedback from all authors	complied and analyzed the data	Analyzed the data	Formal analysis	YES
6161987	29968068	JG	2	designed and piloted the task|oversaw data collection|complied and analyzed the data|oversaw manuscript writing with substantial contributions and feedback from all authors	oversaw manuscript writing with substantial contributions and feedback from all authors	Wrote the paper	Supervision|Writing - Original Draft	YES
6161987	29968068	JP	2	oversaw data collection|complied and analyzed the data	oversaw data collection	Performed the experiments	Investigation|Supervision	YES
6161987	29968068	JP	2	oversaw data collection|complied and analyzed the data	complied and analyzed the data	Analyzed the data	Formal analysis	YES
6161987	29968068	ML	2	designed and piloted the task|complied and analyzed the data	designed and piloted the task	Conceived and designed the experiments	-	YES
6161987	29968068	ML	2	designed and piloted the task|complied and analyzed the data	complied and analyzed the data	Analyzed the data	Formal analysis	YES
6358038	30740597	All authors	2	contributed to critical review of manuscript drafts and reviewed and approved the final manuscript	contributed to critical review of manuscript drafts and reviewed and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6358038	30740597	EH	2	cleaned and analysed the data and drafted the manuscript	cleaned and analysed the data and drafted the manuscript	Analyzed the data|Wrote the paper	Data curation|Formal analysis|Writing - Original Draft	YES
6358038	30740597	JVR	2	conceptualised the study and revised the manuscript	conceptualised the study and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
6358038	30740597	KBP	2	conceptualised and designed the work, analysed the data, and revised the manuscript	conceptualised and designed the work, analysed the data, and revised the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Review & Editing	YES
6358038	30740597	REC	2	contributed statistical analysis code and revised the manuscript	contributed statistical analysis code and revised the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Software|Writing - Review & Editing	YES
6358038	30740597	TDH	2	designed the study and revised the manuscript	designed the study and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
6358038	30740597	TS	2	designed the study and revised the manuscript	designed the study and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
4737733	26838093	All the authors	2	participated in data analysis|contributed to revising the paper until it was submitted for publication	participated in data analysis	Analyzed the data	Formal analysis	YES
4737733	26838093	All the authors	2	participated in data analysis|contributed to revising the paper until it was submitted for publication	contributed to revising the paper until it was submitted for publication	Wrote the paper	Writing - Review & Editing	YES
4737733	26838093	BU	2	participated in data collection	participated in data collection	Performed the experiments	Investigation	YES
4737733	26838093	OI	2	participated in data collection	participated in data collection	Performed the experiments	Investigation	YES
4737733	26838093	OO	2	participated in data collection|drafted the paper	participated in data collection	Performed the experiments	Investigation	YES
4737733	26838093	OO	2	participated in data collection|drafted the paper	drafted the paper	Wrote the paper	Writing - Original Draft	YES
4737733	26838093	OS	2	participated in data collection	participated in data collection	Performed the experiments	Investigation	YES
4737733	26838093	SD	2	participated in data collection	participated in data collection	Performed the experiments	Investigation	YES
5198733	28053700	Angus K. Fadyen	7	Statistical analysis, and manuscript review	Statistical analysis, and manuscript review	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5198733	28053700	Gregory E. Ekatah	7	Concept, design, data collection, analysis, manuscript preparation and editing	Concept, design, data collection, analysis, manuscript preparation and editing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5198733	28053700	Guat Shi Ng	7	Data collection	Data collection	Performed the experiments	Investigation	YES
5198733	28053700	Jeyakumar R. Apollos	7	Concept, design, data collection, analysis, manuscript preparation and editing	Concept, design, data collection, analysis, manuscript preparation and editing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5198733	28053700	Stuart C. Whitelaw	7	Study concept, manuscript review	Study concept, manuscript review	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5808414	29433509	AS	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5808414	29433509	All	PLoS52	enrolled participants signed informed consent	enrolled participants signed informed consent	Performed the experiments	Investigation	YES
5808414	29433509	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5808414	29433509	GM	PLoS52	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5808414	29433509	HVDP	PLoS52	made substantial contributions to data acquisition	made substantial contributions to data acquisition	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5808414	29433509	K Mpalali	PLoS52	assisted with informed consent, sputum induction, and laboratory sample processing	assisted with informed consent, sputum induction, and laboratory sample processing	-	Data curation	YES
5808414	29433509	MM	PLoS52	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5808414	29433509	RG	PLoS52	analyzed the data|made substantial contributions to data acquisition	analyzed the data	Analyzed the data	Formal analysis	YES
5808414	29433509	RG	PLoS52	analyzed the data|made substantial contributions to data acquisition	made substantial contributions to data acquisition	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5808414	29433509	The authors	PLoS52	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5808414	29433509	WS	PLoS52	made substantial contributions to data acquisition	made substantial contributions to data acquisition	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5748541	29077019	Alan Kearney	2	devised the study design|assessed the interventions to measure potential clinical harm|performed the data analysis with	devised the study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5748541	29077019	Alan Kearney	2	devised the study design|assessed the interventions to measure potential clinical harm|performed the data analysis with	assessed the interventions to measure potential clinical harm	Performed the experiments	Investigation	YES
5748541	29077019	Alan Kearney	2	devised the study design|assessed the interventions to measure potential clinical harm|performed the data analysis with	performed the data analysis with	Analyzed the data	Formal analysis	YES
5748541	29077019	Ciaran Halleran	2	devised the study design	devised the study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5748541	29077019	Derina Byrne	2	assessed the interventions to measure potential clinical harm	assessed the interventions to measure potential clinical harm	Performed the experiments	Investigation	YES
5748541	29077019	Elaine Walsh	2	assessed the interventions to measure potential clinical harm	assessed the interventions to measure potential clinical harm	Performed the experiments	Investigation	YES
5748541	29077019	Jennifer Haugh	2	assessed the interventions to measure potential clinical harm	assessed the interventions to measure potential clinical harm	Performed the experiments	Investigation	YES
5748541	29077019	Laura J. Sahm	2	devised the study design|assessed the interventions to measure potential clinical harm|assisted alan kearney performed the data analysis with	devised the study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5748541	29077019	Laura J. Sahm	2	devised the study design|assessed the interventions to measure potential clinical harm|assisted alan kearney performed the data analysis with	assessed the interventions to measure potential clinical harm	Performed the experiments	Investigation	YES
5748541	29077019	Laura J. Sahm	2	devised the study design|assessed the interventions to measure potential clinical harm|assisted alan kearney performed the data analysis with	assisted alan kearney performed the data analysis with	Analyzed the data	Formal analysis	YES
4405357	25897671	AAB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405357	25897671	AAB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405357	25897671	AAB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405357	25897671	AJ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405357	25897671	AJ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405357	25897671	AJ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405357	25897671	BG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405357	25897671	BG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405357	25897671	BG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405357	25897671	BG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405357	25897671	CK	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405357	25897671	CK	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405357	25897671	CL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405357	25897671	CL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405357	25897671	CL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405357	25897671	CL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405357	25897671	CL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405357	25897671	CTN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405357	25897671	CTN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405357	25897671	CTN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405357	25897671	CTN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405357	25897671	CW	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405357	25897671	CW	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405357	25897671	HT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405357	25897671	HT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405357	25897671	HT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405357	25897671	HT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405357	25897671	HT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405357	25897671	NHHH	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405357	25897671	NHHH	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405357	25897671	RK	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405357	25897671	RK	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5264326	28118819	BHG	2	analyzed data|interpreted results of experiments|prepared, edited and approved the final manuscript	analyzed data	Analyzed the data	Formal analysis	YES
5264326	28118819	BHG	2	analyzed data|interpreted results of experiments|prepared, edited and approved the final manuscript	interpreted results of experiments	Analyzed the data	Formal analysis	YES
5264326	28118819	BHG	2	analyzed data|interpreted results of experiments|prepared, edited and approved the final manuscript	prepared, edited and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5264326	28118819	CEL	2	prepared, edited and approved the final manuscript	prepared, edited and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5264326	28118819	KAH	2	performed experiments|prepared, edited and approved the final manuscript	performed experiments	Performed the experiments	Investigation	YES
5264326	28118819	KAH	2	performed experiments|prepared, edited and approved the final manuscript	prepared, edited and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5264326	28118819	KAS	2	conceived and designed the research|performed experiments|analyzed data|interpreted results of experiments|prepared figures|prepared, edited and approved the final manuscript	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5264326	28118819	KAS	2	conceived and designed the research|performed experiments|analyzed data|interpreted results of experiments|prepared figures|prepared, edited and approved the final manuscript	performed experiments	Performed the experiments	Investigation	YES
5264326	28118819	KAS	2	conceived and designed the research|performed experiments|analyzed data|interpreted results of experiments|prepared figures|prepared, edited and approved the final manuscript	analyzed data	Analyzed the data	Formal analysis	YES
5264326	28118819	KAS	2	conceived and designed the research|performed experiments|analyzed data|interpreted results of experiments|prepared figures|prepared, edited and approved the final manuscript	interpreted results of experiments	Analyzed the data	Formal analysis	YES
5264326	28118819	KAS	2	conceived and designed the research|performed experiments|analyzed data|interpreted results of experiments|prepared figures|prepared, edited and approved the final manuscript	prepared figures	-	Visualization	YES
5264326	28118819	KAS	2	conceived and designed the research|performed experiments|analyzed data|interpreted results of experiments|prepared figures|prepared, edited and approved the final manuscript	prepared, edited and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5264326	28118819	MET	2	analyzed data|interpreted results of experiments|prepared figures|prepared, edited and approved the final manuscript	analyzed data	Analyzed the data	Formal analysis	YES
5264326	28118819	MET	2	analyzed data|interpreted results of experiments|prepared figures|prepared, edited and approved the final manuscript	interpreted results of experiments	Analyzed the data	Formal analysis	YES
5264326	28118819	MET	2	analyzed data|interpreted results of experiments|prepared figures|prepared, edited and approved the final manuscript	prepared figures	-	Visualization	YES
5264326	28118819	MET	2	analyzed data|interpreted results of experiments|prepared figures|prepared, edited and approved the final manuscript	prepared, edited and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5264326	28118819	TCG	2	conceived and designed the research|performed experiments|analyzed data|interpreted results of experiments|prepared figures|prepared, edited and approved the final manuscript	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5264326	28118819	TCG	2	conceived and designed the research|performed experiments|analyzed data|interpreted results of experiments|prepared figures|prepared, edited and approved the final manuscript	performed experiments	Performed the experiments	Investigation	YES
5264326	28118819	TCG	2	conceived and designed the research|performed experiments|analyzed data|interpreted results of experiments|prepared figures|prepared, edited and approved the final manuscript	analyzed data	Analyzed the data	Formal analysis	YES
5264326	28118819	TCG	2	conceived and designed the research|performed experiments|analyzed data|interpreted results of experiments|prepared figures|prepared, edited and approved the final manuscript	interpreted results of experiments	Analyzed the data	Formal analysis	YES
5264326	28118819	TCG	2	conceived and designed the research|performed experiments|analyzed data|interpreted results of experiments|prepared figures|prepared, edited and approved the final manuscript	prepared figures	-	Visualization	YES
5264326	28118819	TCG	2	conceived and designed the research|performed experiments|analyzed data|interpreted results of experiments|prepared figures|prepared, edited and approved the final manuscript	prepared, edited and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5264326	28118819	XH	2	analyzed data|interpreted results of experiments	analyzed data	Analyzed the data	Formal analysis	YES
5264326	28118819	XH	2	analyzed data|interpreted results of experiments	interpreted results of experiments	Analyzed the data	Formal analysis	YES
5532446	28804492	HL	PLoS52	collected samples and analyzed the data	collected samples and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5532446	28804492	JW	PLoS52	collected samples and analyzed the data	collected samples and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5532446	28804492	LJ	PLoS52	performed the experiments, analyzed the data	performed the experiments, analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5532446	28804492	QG	PLoS52	conceived and designed the experiments, analyzed the data, wrote the paper, prepared figures and tables|have contributed equally to this work	conceived and designed the experiments, analyzed the data, wrote the paper, prepared figures and tables	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Visualization|Writing - Original Draft	YES
5532446	28804492	QG	PLoS52	conceived and designed the experiments, analyzed the data, wrote the paper, prepared figures and tables|have contributed equally to this work	have contributed equally to this work	-	-	NO
5532446	28804492	RG	PLoS52	contributed distributional data and reviewed and wrote parts of the paper	contributed distributional data and reviewed and wrote parts of the paper	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Original Draft|Writing - Review & Editing	YES
5532446	28804492	SC	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5532446	28804492	YL	PLoS52	performed the experiments, analyzed the data|have contributed equally to this work	performed the experiments, analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5532446	28804492	YL	PLoS52	performed the experiments, analyzed the data|have contributed equally to this work	have contributed equally to this work	-	-	NO
5532446	28804492	ZG	PLoS52	performed the experiments, analyzed the data	performed the experiments, analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5748542	29104235	Kelsey Noss	PLoS52	conceived and designed the experiments|analyzed the data|contributed reagents/materials/analysis tools|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5748542	29104235	Kelsey Noss	PLoS52	conceived and designed the experiments|analyzed the data|contributed reagents/materials/analysis tools|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5748542	29104235	Kelsey Noss	PLoS52	conceived and designed the experiments|analyzed the data|contributed reagents/materials/analysis tools|wrote the paper	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5748542	29104235	Kelsey Noss	PLoS52	conceived and designed the experiments|analyzed the data|contributed reagents/materials/analysis tools|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5748542	29104235	Sandra M. Aguero	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5748542	29104235	Travis Reinaker	PLoS52	conceived and designed the experiments|analyzed the data|contributed reagents/materials/analysis tools|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5748542	29104235	Travis Reinaker	PLoS52	conceived and designed the experiments|analyzed the data|contributed reagents/materials/analysis tools|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5748542	29104235	Travis Reinaker	PLoS52	conceived and designed the experiments|analyzed the data|contributed reagents/materials/analysis tools|wrote the paper	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5748542	29104235	Travis Reinaker	PLoS52	conceived and designed the experiments|analyzed the data|contributed reagents/materials/analysis tools|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6161999	29423550	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6161999	29423550	CRA	2	have contributed to idea development and the writing	have contributed to idea development and the writing	Conceived and designed the experiments|Wrote the paper	Conceptualization	YES
6161999	29423550	DGA	2	conceived the study and wrote the paper	conceived the study and wrote the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
6161999	29423550	MLP	2	have contributed to idea development and the writing	have contributed to idea development and the writing	Conceived and designed the experiments|Wrote the paper	Conceptualization	YES
6161999	29423550	NJ	2	faculty, swedish university of agricultural sciences	faculty, swedish university of agricultural sciences	-	-	NO
6161999	29423550	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
6161999	29423550	Wildlife Service	2	the wildlife management institute	the wildlife management institute	-	-	NO
5199157	28053701	Antonio Taveira Gomes	7	data analysis or interpretation	data analysis or interpretation	Analyzed the data	Formal analysis	YES
5199157	28053701	Joao Correia Pinto	7	writing the paper (pathology description and discussion	writing the paper (pathology description and discussion	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5199157	28053701	Pedro Koch	7	data analysis or interpretation	data analysis or interpretation	Analyzed the data	Formal analysis	YES
5199157	28053701	Rita Peixoto	7	data collection, writing the paper	data collection, writing the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5199157	28053701	Virginia Soares	7	data analysis or interpretation, writing the paper	data analysis or interpretation, writing the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4740352	26842728	AMH	2	wrote the initial draft of the publication	wrote the initial draft of the publication	Wrote the paper	Writing - Original Draft	YES
4740352	26842728	All the authors	2	critically reviewed and approved the final version of the publication	critically reviewed and approved the final version of the publication	-	-	NO
4405358	25898367	BHL	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4405358	25898367	DLN	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405358	25898367	DLN	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405358	25898367	GHK	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405358	25898367	GHK	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405358	25898367	HKK	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4405358	25898367	JML	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4405358	25898367	KI	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4405358	25898367	KMH	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405358	25898367	MSK	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405358	25898367	MTC	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405358	25898367	SJ	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4405358	25898367	SWS	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5844086	29519243	AB	2	developed the audit questionnaire after consultation with the core working group for this project|also developed the database, conducted data analysis and contributed to the writing of the manuscript	developed the audit questionnaire after consultation with the core working group for this project	-	-	NO
5844086	29519243	AB	2	developed the audit questionnaire after consultation with the core working group for this project|also developed the database, conducted data analysis and contributed to the writing of the manuscript	also developed the database, conducted data analysis and contributed to the writing of the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Software|Writing - Original Draft	YES
5844086	29519243	Albion Centre	2	is a facility of south eastern sydney local hospital network	is a facility of south eastern sydney local hospital network	-	-	NO
5844086	29519243	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5844086	29519243	JP	2	edited the manuscript and assisted in the development of the data collection tool	edited the manuscript and assisted in the development of the data collection tool	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5844086	29519243	MD	2	developed the database, analysed the data, undertook the regression models, constructed the dag model, summarized the results, and helped edit the paper	developed the database, analysed the data, undertook the regression models, constructed the dag model, summarized the results, and helped edit the paper	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Software|Writing - Original Draft|Writing - Review & Editing	YES
5844086	29519243	RB	2	contributed to the study design and interpretation of the data	contributed to the study design and interpretation of the data	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Methodology|Resources	YES
5844086	29519243	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5844086	29519243	VF	2	contributed to the concept design including data collection form, data collection on designated patients, contribution to draft paper	contributed to the concept design including data collection form, data collection on designated patients, contribution to draft paper	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Investigation|Resources|Writing - Original Draft	YES
4477445	26180817	Alison D. Grant	2	contributed to study concept and design, epidemiological advice, parent study design and implementation, and paper writing	contributed to study concept and design, epidemiological advice, parent study design and implementation, and paper writing	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology	YES
4477445	26180817	Gavin J. Churchyard	2	contributed to study design of this and parent studies, epidemiological advice, and paper review	contributed to study design of this and parent studies, epidemiological advice, and paper review	Conceived and designed the experiments	Methodology	YES
4477445	26180817	Gey van Pittius	2	carried out laboratory work, contributed microbiology advice, and reviewed the paper	carried out laboratory work, contributed microbiology advice, and reviewed the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4477445	26180817	James J. Lewis	2	contributed to data management, parent study implementation, statistical and epidemiological advice, and paper review	contributed to data management, parent study implementation, statistical and epidemiological advice, and paper review	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation|Project administration	YES
4477445	26180817	Katherine L. Fielding	2	contributed to study design, parent study design and implementation, epidemiological input, and paper review	contributed to study design, parent study design and implementation, epidemiological input, and paper review	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4477445	26180817	Violet N. Chihota	2	contributed to study design, parent study implementation, laboratory work, and paper writing	contributed to study design, parent study implementation, laboratory work, and paper writing	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology	YES
5748543	29113107	Christopher Wood	2	reviewed and made substantial contributions to the finalized version of the manuscript	reviewed and made substantial contributions to the finalized version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5748543	29113107	Joe M. Swanson	2	reviewed and made substantial contributions to the finalized version of the manuscript	reviewed and made substantial contributions to the finalized version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5748543	29113107	Rex O. Brown	2	reviewed and made substantial contributions to the finalized version of the manuscript	reviewed and made substantial contributions to the finalized version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5748543	29113107	Roland N. Dickerson	2	conceived the project and prepared the first draft and subsequent revisions to the manuscript	conceived the project and prepared the first draft and subsequent revisions to the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
5532450	28804491	All authors	2	contributed to the acquisition and interpretation of available literature and the conception of the work	contributed to the acquisition and interpretation of available literature and the conception of the work	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation	YES
5532450	28804491	JC	2	wrote the manuscript, and all authors reviewed and revised the manuscript and approved this final version	wrote the manuscript, and all authors reviewed and revised the manuscript and approved this final version	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5532450	28804491	SL	2	wrote the manuscript, and all authors reviewed and revised the manuscript and approved this final version|contributed equally to this work	wrote the manuscript, and all authors reviewed and revised the manuscript and approved this final version	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5532450	28804491	SL	2	wrote the manuscript, and all authors reviewed and revised the manuscript and approved this final version|contributed equally to this work	contributed equally to this work	-	-	NO
5532450	28804491	XW	2	wrote the manuscript, and all authors reviewed and revised the manuscript and approved this final version|contributed equally to this work	wrote the manuscript, and all authors reviewed and revised the manuscript and approved this final version	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5532450	28804491	XW	2	wrote the manuscript, and all authors reviewed and revised the manuscript and approved this final version|contributed equally to this work	contributed equally to this work	-	-	NO
5219587	28070330	Arik Eisenkraft	2	contributed in performing the study, acquisition of data, and final approval of the version to be submitted	contributed in performing the study, acquisition of data, and final approval of the version to be submitted	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5219587	28070330	Ben-Zion Bobrovsky	2	contributed in the analysis and interpretation of data, revising the article critically for important intellectual content final approval of the version to be submitted	contributed in the analysis and interpretation of data, revising the article critically for important intellectual content final approval of the version to be submitted	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
5219587	28070330	David Kushnir	2	contributed in performing the study, acquisition of data, and final approval of the version to be submitted	contributed in performing the study, acquisition of data, and final approval of the version to be submitted	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5219587	28070330	E Gabbay	2	contributed in the analysis and interpretation of data, drafting the article and final approval of the version to be submitted	contributed in the analysis and interpretation of data, drafting the article and final approval of the version to be submitted	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
5219587	28070330	Elon Glassberg	2	contributed in the conception and design of the study, analysis and interpretation of data, drafting the article and final approval of the version to be submitted	contributed in the conception and design of the study, analysis and interpretation of data, drafting the article and final approval of the version to be submitted	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Methodology|Resources|Writing - Original Draft	YES
5219587	28070330	Gal Yaniv	2	contributed in performing the study, acquisition of data, and final approval of the version to be submitted	contributed in performing the study, acquisition of data, and final approval of the version to be submitted	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5219587	28070330	Linn Wagnert-Avraham	2	contributed in performing the study, acquisition of data, and final approval of the version to be submitted	contributed in performing the study, acquisition of data, and final approval of the version to be submitted	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5219587	28070330	Roy Nadler	2	contributed in the conception and design of the study, acquisition of data, analysis and interpretation of data, drafting the article and final approval of the version to be submitted	contributed in the conception and design of the study, acquisition of data, analysis and interpretation of data, drafting the article and final approval of the version to be submitted	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
5219587	28070330	Uri Gabbay	2	contributed in the analysis and interpretation of data, drafting the article and final approval of the version to be submitted	contributed in the analysis and interpretation of data, drafting the article and final approval of the version to be submitted	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
6162003	29886522	All authors	2	had full access to the data included in the paper, interpreted the data, and critically reviewed drafts of the paper|read and approved the final manuscript	had full access to the data included in the paper, interpreted the data, and critically reviewed drafts of the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
6162003	29886522	All authors	2	had full access to the data included in the paper, interpreted the data, and critically reviewed drafts of the paper|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6162003	29886522	Copernicus Group	2	for researchers who meet the criteria for access to confidential data	for researchers who meet the criteria for access to confidential data	-	-	NO
6162003	29886522	PhRMA	2	principles for responsible sharing of clinical trial data guidelines and as required by applicable legislation	principles for responsible sharing of clinical trial data guidelines and as required by applicable legislation	-	-	NO
6162003	29886522	WIRB	2	for researchers who meet the criteria for access to confidential data	for researchers who meet the criteria for access to confidential data	-	-	NO
5853105	29544508	AAS	2	wellcome trust or the uk government	wellcome trust or the uk government	-	-	NO
5853105	29544508	ART	2	authors declare that they have no competing interests	authors declare that they have no competing interests	-	-	NO
5853105	29544508	All authors	2	reviewed manuscript for publication|read and approved the final manuscript	reviewed manuscript for publication	Wrote the paper	Writing - Review & Editing	YES
5853105	29544508	All authors	2	reviewed manuscript for publication|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5853105	29544508	DN	2	contributed to the conceptualization and execution of the review|drafted the manuscript	contributed to the conceptualization and execution of the review	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5853105	29544508	DN	2	contributed to the conceptualization and execution of the review|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5853105	29544508	Damalie Nakanjako	2	through a group leader award	through a group leader award	-	Supervision	YES
5853105	29544508	MJ	2	contributed to the conceptualization and execution of the review	contributed to the conceptualization and execution of the review	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5853105	29544508	NEPAD	2	wellcome trust or the uk government	wellcome trust or the uk government	-	-	NO
5853105	29544508	RN	2	contributed to the conceptualization and execution of the review|drafted the manuscript	contributed to the conceptualization and execution of the review	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5853105	29544508	RN	2	contributed to the conceptualization and execution of the review|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5853105	29544508	Rose Nabatanzi	2	through a group leader award	through a group leader award	-	Supervision	YES
5853105	29544508	SC	2	contributed to the conceptualization and execution of the review	contributed to the conceptualization and execution of the review	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5853105	29544508	SRJ	2	contributed to the conceptualization and execution of the review	contributed to the conceptualization and execution of the review	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5267385	28122517	GKS	PLoS52	designed the study|performed the experiments|conducted the analyses|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5267385	28122517	GKS	PLoS52	designed the study|performed the experiments|conducted the analyses|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5267385	28122517	GKS	PLoS52	designed the study|performed the experiments|conducted the analyses|wrote the manuscript	conducted the analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5267385	28122517	GKS	PLoS52	designed the study|performed the experiments|conducted the analyses|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5267385	28122517	TW	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5267385	28122517	WPP	PLoS52	designed the study|conducted the analyses|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5267385	28122517	WPP	PLoS52	designed the study|conducted the analyses|wrote the manuscript	conducted the analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5267385	28122517	WPP	PLoS52	designed the study|conducted the analyses|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4405359	25898361	BB	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405359	25898361	BP	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405359	25898361	BV	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405359	25898361	BV	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405359	25898361	DC	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405359	25898361	DC	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405359	25898361	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405359	25898361	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405359	25898361	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405359	25898361	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405359	25898361	SV	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4405359	25898361	SV	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4744323	26850270	AVDS	PLoS52	conceived and designed the study|wrote the paper	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4744323	26850270	AVDS	PLoS52	conceived and designed the study|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4744323	26850270	CWH	PLoS52	conceived and designed the study|analyzed the data	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4744323	26850270	CWH	PLoS52	conceived and designed the study|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
4744323	26850270	ERB	PLoS52	conceived and designed the study|analyzed the data|wrote the paper	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4744323	26850270	ERB	PLoS52	conceived and designed the study|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
4744323	26850270	ERB	PLoS52	conceived and designed the study|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4744323	26850270	JMM	PLoS52	chaired the protocol and implemented the trial	chaired the protocol and implemented the trial	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4744323	26850270	JMP	PLoS52	chaired the protocol and implemented the trial	chaired the protocol and implemented the trial	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4744323	26850270	KG	PLoS52	chaired the protocol and implemented the trial	chaired the protocol and implemented the trial	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4744323	26850270	KL	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
4744323	26850270	MAM	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
4744323	26850270	MZC	PLoS52	chaired the protocol and implemented the trial	chaired the protocol and implemented the trial	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5219610	28070329	A Cuesta	7	study concept and design, data collection, data analysis, writing. N van der Wielen: data collection, data analysis, writing	study concept and design, data collection, data analysis, writing. N van der Wielen: data collection, data analysis, writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology	YES
5219610	28070329	J Straatman	7	data collection, data analysis, writing. DL van der Peet: study concept and design, data collection, data analysis, writing	data collection, data analysis, writing. DL van der Peet: study concept and design, data collection, data analysis, writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology	YES
5748544	29120385	All authors	2	contributed to the manuscript in a significant way|of the manuscript have read and agreed to its content and are accountable for all aspects of the accuracy and integrity of the manuscript in accordance with icmje criteria	contributed to the manuscript in a significant way	-	-	NO
5748544	29120385	All authors	2	contributed to the manuscript in a significant way|of the manuscript have read and agreed to its content and are accountable for all aspects of the accuracy and integrity of the manuscript in accordance with icmje criteria	of the manuscript have read and agreed to its content and are accountable for all aspects of the accuracy and integrity of the manuscript in accordance with icmje criteria	-	-	NO
5748544	29120385	Damian Swieczkowski	2	designed the study, prepared and revised the manuscript	designed the study, prepared and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5748544	29120385	Milosz Jaguszewski	2	supervised the project	supervised the project	-	Supervision	YES
5748544	29120385	Piotr Merks	2	supervised the project	supervised the project	-	Supervision	YES
5748544	29120385	Urszula Religioni	2	designed the study and collected data	designed the study and collected data	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5534448	28824663	CLi	PLoS52	performed the research	performed the research	Performed the experiments	Investigation	YES
5534448	28824663	CLu	PLoS52	performed the research	performed the research	Performed the experiments	Investigation	YES
5534448	28824663	CZ	PLoS52	modified the paper	modified the paper	Wrote the paper	Writing - Review & Editing	YES
5534448	28824663	PM	PLoS52	performed the research|wrote the paper	performed the research	Performed the experiments	Investigation	YES
5534448	28824663	PM	PLoS52	performed the research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5534448	28824663	WW	PLoS52	designed the research|modified the paper	designed the research	Conceived and designed the experiments	Methodology	YES
5534448	28824663	WW	PLoS52	designed the research|modified the paper	modified the paper	Wrote the paper	Writing - Review & Editing	YES
5534448	28824663	XC	PLoS52	designed the research|wrote the paper	designed the research	Conceived and designed the experiments	Methodology	YES
5534448	28824663	XC	PLoS52	designed the research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5534448	28824663	YM	PLoS52	performed the research	performed the research	Performed the experiments	Investigation	YES
5534448	28824663	ZX	PLoS52	performed the research	performed the research	Performed the experiments	Investigation	YES
5363392	28451335	All authors	2	contributed to the manuscript	contributed to the manuscript	-	-	NO
5363392	28451335	B.S.	2	performed the scanning probe measurements	performed the scanning probe measurements	Performed the experiments	Investigation	YES
5363392	28451335	G.M.	2	performed the scanning probe measurements	performed the scanning probe measurements	Performed the experiments	Investigation	YES
5363392	28451335	J.D.K.	2	conceived the experiments	conceived the experiments	Conceived and designed the experiments	Conceptualization	YES
5363392	28451335	L.G.	2	performed the scanning probe measurements	performed the scanning probe measurements	Performed the experiments	Investigation	YES
5363392	28451335	S.F.	2	performed the scanning probe measurements	performed the scanning probe measurements	Performed the experiments	Investigation	YES
5363392	28451335	Y.Z.	2	conceived the experiments	conceived the experiments	Conceived and designed the experiments	Conceptualization	YES
5872568	29592818	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5872568	29592818	CN	2	analyzed data interpreted the results and wrote the manuscript	analyzed data interpreted the results and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5872568	29592818	GM	2	analyzed data interpreted the results and wrote the manuscript	analyzed data interpreted the results and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5872568	29592818	GT	2	analyzed data interpreted the results and wrote the manuscript	analyzed data interpreted the results and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5872568	29592818	PC	2	were responsible for data collection and data entry	were responsible for data collection and data entry	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5872568	29592818	ST	2	conceived the study|were responsible for data collection and data entry	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5872568	29592818	ST	2	conceived the study|were responsible for data collection and data entry	were responsible for data collection and data entry	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5872568	29592818	SY	2	conceived the study|analyzed data interpreted the results and wrote the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5872568	29592818	SY	2	conceived the study|analyzed data interpreted the results and wrote the manuscript	analyzed data interpreted the results and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5872568	29592818	VK	2	conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5219614	28070328	All	1	Data analysis/interpretation	Data analysis/interpretation	Analyzed the data	Formal analysis	YES
5219614	28070328	HA	1	Review	Review	-	-	NO
5219614	28070328	KF	1	Data collection	Data collection	Performed the experiments	Investigation	YES
5219614	28070328	MT	1	Paper writing|Review	Paper writing	Wrote the paper	-	YES
5219614	28070328	MT	1	Paper writing|Review	Review	-	-	NO
5219614	28070328	MW	1	Study design|Data collection|Paper writing	Study design	Conceived and designed the experiments	Methodology	YES
5219614	28070328	MW	1	Study design|Data collection|Paper writing	Data collection	Performed the experiments	Investigation	YES
5219614	28070328	MW	1	Study design|Data collection|Paper writing	Paper writing	Wrote the paper	-	YES
4748109	26861115	AS	2	are co-investigators	are co-investigators	-	-	NO
4748109	26861115	EB	2	led the process of data analysis|conducted statistical analysis and co-wrote the manuscript	led the process of data analysis	Analyzed the data	Data curation|Formal analysis	YES
4748109	26861115	EB	2	led the process of data analysis|conducted statistical analysis and co-wrote the manuscript	conducted statistical analysis and co-wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4748109	26861115	EM	2	are co-investigators	are co-investigators	-	-	NO
4748109	26861115	FD	2	is the primary investigator of the iedea-wa collaboration and provided critical revision for important intellectual content	is the primary investigator of the iedea-wa collaboration and provided critical revision for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4748109	26861115	MM	2	led the process of data analysis|is also a member of the central team of the art-cc collaboration and provided substantial advice during statistical analysis and commented the manuscript	led the process of data analysis	Analyzed the data	Data curation|Formal analysis	YES
4748109	26861115	MM	2	led the process of data analysis|is also a member of the central team of the art-cc collaboration and provided substantial advice during statistical analysis and commented the manuscript	is also a member of the central team of the art-cc collaboration and provided substantial advice during statistical analysis and commented the manuscript	Analyzed the data	Formal analysis	YES
4748109	26861115	SPE	2	are co-investigators	are co-investigators	-	-	NO
3580924	23476138	A. Gupta	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
3580924	23476138	W. Cao	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
6162004	29619634	All	2	grants were unrestricted with respect to the development or execution of the trial, study design, analysis plan and dissemination of study results	grants were unrestricted with respect to the development or execution of the trial, study design, analysis plan and dissemination of study results	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
6162004	29619634	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6162004	29619634	CTN	2	conceptualized and designed the study|raised funding and initiated the trial	conceptualized and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6162004	29619634	CTN	2	conceptualized and designed the study|raised funding and initiated the trial	raised funding and initiated the trial	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
6162004	29619634	HEP	2	conceptualized and designed the study	conceptualized and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6162004	29619634	MB	2	conceptualized and designed the study	conceptualized and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6162004	29619634	OMD	2	conceptualized and designed the study	conceptualized and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6162004	29619634	PKE	2	conceptualized and designed the study|raised funding and initiated the trial|drafted the manuscript	conceptualized and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6162004	29619634	PKE	2	conceptualized and designed the study|raised funding and initiated the trial|drafted the manuscript	raised funding and initiated the trial	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
6162004	29619634	PKE	2	conceptualized and designed the study|raised funding and initiated the trial|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
6162004	29619634	RWL	2	conceptualized and designed the study	conceptualized and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6162004	29619634	T Nielsen	2	has no conflicts of interest to declare	has no conflicts of interest to declare	-	-	NO
4405360	25898321	BW	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405360	25898321	BW	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405360	25898321	DFH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405360	25898321	DFH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405360	25898321	DFH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405360	25898321	DW	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405360	25898321	DW	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405360	25898321	EMS	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405360	25898321	EMS	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405360	25898321	EMS	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405360	25898321	IBH	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405360	25898321	IBH	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405360	25898321	JSC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405360	25898321	JSC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405360	25898321	JSC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405360	25898321	RR	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405360	25898321	RR	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405360	25898321	RR	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405360	25898321	RR	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405360	25898321	RSCL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405360	25898321	RSCL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405360	25898321	RSCL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405360	25898321	SLN	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405360	25898321	SLN	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5748545	29168795	All authors	2	contributed to the design of the study and the analysis of the results	contributed to the design of the study and the analysis of the results	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5748545	29168795	Meghan Burgess	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5748545	29168795	Minji Sohn	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5748545	29168795	Mohamed Bazzi	2	provided revisions and comments	provided revisions and comments	Wrote the paper	Writing - Review & Editing	YES
5534461	28824679	AC	2	performed the microarray analysis	performed the microarray analysis	Performed the experiments	Investigation	YES
5534461	28824679	AE	2	performed the cellular localization of the yfp-slwrky3 fusion protein	performed the cellular localization of the yfp-slwrky3 fusion protein	Performed the experiments	Investigation	YES
5534461	28824679	EG	2	performed the physiological characterization of the selected plant material	performed the physiological characterization of the selected plant material	Performed the experiments	Investigation	YES
5534461	28824679	EZ	2	performed the hormonal analysis of the plant material and helped in the treatment and interpretation of the data	performed the hormonal analysis of the plant material and helped in the treatment and interpretation of the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5534461	28824679	IH	2	designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
5534461	28824679	IL-V	2	performed the protein purification and protein binding microarray	performed the protein purification and protein binding microarray	Performed the experiments	Investigation	YES
5534461	28824679	JF-Z	2	performed the protein purification and protein binding microarray	performed the protein purification and protein binding microarray	Performed the experiments	Investigation	YES
5534461	28824679	PD	2	performed the hormonal analysis of the plant material and helped in the treatment and interpretation of the data	performed the hormonal analysis of the plant material and helped in the treatment and interpretation of the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5534461	28824679	RS	2	performed the protein purification and protein binding microarray	performed the protein purification and protein binding microarray	Performed the experiments	Investigation	YES
5534461	28824679	SL	2	designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
5534461	28824679	VM	2	performed the hormonal analysis of the plant material and helped in the treatment and interpretation of the data	performed the hormonal analysis of the plant material and helped in the treatment and interpretation of the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5534461	28824679	YM	2	designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
5267397	28122508	ABF	2	conceived of and designed the project	conceived of and designed the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5267397	28122508	CH	2	performed experiments and analyzed data	performed experiments and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5267397	28122508	CPY	2	performed experiments and analyzed data	performed experiments and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5267397	28122508	DJF	2	performed bioinformatics analyses	performed bioinformatics analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5267397	28122508	JSW	2	performed experiments and analyzed data	performed experiments and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5267397	28122508	KH	2	performed bioinformatics analyses	performed bioinformatics analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5267397	28122508	MAO	2	conceived of and designed the project	conceived of and designed the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5267397	28122508	MWW	2	provided experimental protocols and data analysis	provided experimental protocols and data analysis	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Methodology|Resources	YES
5267397	28122508	NKK	2	performed experiments and analyzed data	performed experiments and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5267397	28122508	SAN	2	provided experimental protocols and data analysis	provided experimental protocols and data analysis	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Methodology|Resources	YES
5237771	28119778	Ghazi Al Edwan	CRediT	Study concept and design|Supervision	Study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5237771	28119778	Ghazi Al Edwan	CRediT	Study concept and design|Supervision	Supervision	-	Supervision	YES
5237771	28119778	M. Atta	CRediT	Acquisition of data|Analysis and interpretation of data|Drafting of the manuscript	Acquisition of data	Performed the experiments	Investigation	YES
5237771	28119778	M. Atta	CRediT	Acquisition of data|Analysis and interpretation of data|Drafting of the manuscript	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
5237771	28119778	M. Atta	CRediT	Acquisition of data|Analysis and interpretation of data|Drafting of the manuscript	Drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
5237771	28119778	Muheilan Mustafa Muheilan	CRediT	Acquisition of data|Analysis and interpretation of data|Drafting of the manuscript|Statistical analysis	Acquisition of data	Performed the experiments	Investigation	YES
5237771	28119778	Muheilan Mustafa Muheilan	CRediT	Acquisition of data|Analysis and interpretation of data|Drafting of the manuscript|Statistical analysis	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
5237771	28119778	Muheilan Mustafa Muheilan	CRediT	Acquisition of data|Analysis and interpretation of data|Drafting of the manuscript|Statistical analysis	Drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
5237771	28119778	Muheilan Mustafa Muheilan	CRediT	Acquisition of data|Analysis and interpretation of data|Drafting of the manuscript|Statistical analysis	Statistical analysis	Analyzed the data	Formal analysis	YES
5237771	28119778	Omar Nabeeh	CRediT	Acquisition of data|Analysis and interpretation of data|Drafting of the manuscript	Acquisition of data	Performed the experiments	Investigation	YES
5237771	28119778	Omar Nabeeh	CRediT	Acquisition of data|Analysis and interpretation of data|Drafting of the manuscript	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
5237771	28119778	Omar Nabeeh	CRediT	Acquisition of data|Analysis and interpretation of data|Drafting of the manuscript	Drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
4478363	26171389	Jian-Rong Wang	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
4478363	26171389	Yang-Yuan Li	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
4405361	25898128	HAV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Approved final version of manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405361	25898128	HAV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Approved final version of manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4405361	25898128	HAV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Approved final version of manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405361	25898128	HAV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Approved final version of manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405361	25898128	HAV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Approved final version of manuscript	Approved final version of manuscript	-	-	NO
4405361	25898128	IMVLG	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper|Approved final version of manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405361	25898128	IMVLG	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper|Approved final version of manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405361	25898128	IMVLG	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper|Approved final version of manuscript	Approved final version of manuscript	-	-	NO
4405361	25898128	RL	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Approved final version of manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405361	25898128	RL	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Approved final version of manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4405361	25898128	RL	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Approved final version of manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405361	25898128	RL	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Approved final version of manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405361	25898128	RL	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Approved final version of manuscript	Approved final version of manuscript	-	-	NO
4405361	25898128	RMAP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Approved final version of manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405361	25898128	RMAP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Approved final version of manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4405361	25898128	RMAP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Approved final version of manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405361	25898128	RMAP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Approved final version of manuscript	Approved final version of manuscript	-	-	NO
4405361	25898128	SDD	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Approved final version of manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405361	25898128	SDD	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Approved final version of manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4405361	25898128	SDD	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Approved final version of manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405361	25898128	SDD	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Approved final version of manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405361	25898128	SDD	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Approved final version of manuscript	Approved final version of manuscript	-	-	NO
526767	15491493	AB	2	participated in databases design|drafted the manuscript	participated in databases design	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
526767	15491493	AB	2	participated in databases design|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
526767	15491493	AM	2	did all of the programming	did all of the programming	Contributed reagents/materials/analysis tools	Software	YES
526767	15491493	APK	2	performed extensive testing of the database	performed extensive testing of the database	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
526767	15491493	DFL	2	performed extensive testing of the database	performed extensive testing of the database	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
526767	15491493	DG	2	performed extensive testing of the database	performed extensive testing of the database	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
526767	15491493	EG	2	participated in databases design|performed extensive testing of the database|drafted the manuscript	participated in databases design	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
526767	15491493	EG	2	participated in databases design|performed extensive testing of the database|drafted the manuscript	performed extensive testing of the database	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
526767	15491493	EG	2	participated in databases design|performed extensive testing of the database|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
526767	15491493	GI	2	performed extensive testing of the database	performed extensive testing of the database	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
526767	15491493	JEBW	2	participated in databases design|drafted the manuscript	participated in databases design	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
526767	15491493	JEBW	2	participated in databases design|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
526767	15491493	JT	2	participated in databases design	participated in databases design	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
526767	15491493	KT	2	did all of the programming	did all of the programming	Contributed reagents/materials/analysis tools	Software	YES
526767	15491493	LU	2	did all of the programming	did all of the programming	Contributed reagents/materials/analysis tools	Software	YES
526767	15491493	MJ	2	performed extensive testing of the database	performed extensive testing of the database	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
526767	15491493	PD	2	performed extensive testing of the database|drafted the manuscript	performed extensive testing of the database	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
526767	15491493	PD	2	performed extensive testing of the database|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
526767	15491493	TW	2	did all of the programming|drafted the manuscript	did all of the programming	Contributed reagents/materials/analysis tools	Software	YES
526767	15491493	TW	2	did all of the programming|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5237772	28119777	J. Krones	2	conceived and designed the study and collected, analyzed and interpreted the data|wrote the manuscript and provided critical revisions that were important for the intellectual content	conceived and designed the study and collected, analyzed and interpreted the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation|Methodology	YES
5237772	28119777	J. Krones	2	conceived and designed the study and collected, analyzed and interpreted the data|wrote the manuscript and provided critical revisions that were important for the intellectual content	wrote the manuscript and provided critical revisions that were important for the intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5748546	29211054	J Seubert	2	conceived and designed the focus groups, analysed the results, and wrote the paper	conceived and designed the focus groups, analysed the results, and wrote the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
5748546	29211054	Kerry Whitelaw	2	performed duplicate analysis of data	performed duplicate analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5748546	29211054	M Clifford	2	contributed to analysis and write up of the paper	contributed to analysis and write up of the paper	Wrote the paper	Writing - Original Draft	YES
5878417	29604955	All authors	2	critically appraised and reviewed the manuscript submitted for publication|read and approved the final manuscript	critically appraised and reviewed the manuscript submitted for publication	Wrote the paper	Writing - Review & Editing	YES
5878417	29604955	All authors	2	critically appraised and reviewed the manuscript submitted for publication|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5878417	29604955	EK	2	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5878417	29604955	JA	2	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5878417	29604955	JB	2	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5878417	29604955	JC	2	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5878417	29604955	LNK	2	gave strategic direction to have this study conducted	gave strategic direction to have this study conducted	Performed the experiments	Investigation|Supervision	YES
5878417	29604955	MR	2	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5878417	29604955	SS	2	perceived the study, conducted the study, performed the statistical analysis and drafted the manuscript	perceived the study, conducted the study, performed the statistical analysis and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5878417	29604955	TNN	2	participated in the design of the study and reviewed the manuscript	participated in the design of the study and reviewed the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5534469	28824664	MAS	2	for pm2b gene	for pm2b gene	-	-	NO
4751409	26869359	AM	2	contributed to acquisition of data|contributed to critical revision of the manuscript for important intellectual content	contributed to acquisition of data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4751409	26869359	AM	2	contributed to acquisition of data|contributed to critical revision of the manuscript for important intellectual content	contributed to critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4751409	26869359	GL	2	contributed to critical revision of the manuscript for important intellectual content	contributed to critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4751409	26869359	JB	2	contributed to acquisition of data|obtained funding	contributed to acquisition of data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4751409	26869359	JB	2	contributed to acquisition of data|obtained funding	obtained funding	-	Funding acquisition	YES
5247275	28127423	Nam Kyu Kim	1	Study supervision	Study supervision	-	Supervision	YES
6162005	30198055	AEV	2	designed the brain study|wrote the protocol for the present study|supervised the drafted the manuscript under|report no competing interests	designed the brain study	Conceived and designed the experiments	Methodology	YES
6162005	30198055	AEV	2	designed the brain study|wrote the protocol for the present study|supervised the drafted the manuscript under|report no competing interests	wrote the protocol for the present study	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
6162005	30198055	AEV	2	designed the brain study|wrote the protocol for the present study|supervised the drafted the manuscript under|report no competing interests	supervised the drafted the manuscript under	Wrote the paper	Supervision|Writing - Original Draft	YES
6162005	30198055	AEV	2	designed the brain study|wrote the protocol for the present study|supervised the drafted the manuscript under|report no competing interests	report no competing interests	-	-	NO
6162005	30198055	All	2	participants gave written, informed consent	participants gave written, informed consent	Wrote the paper	Writing - Original Draft	YES
6162005	30198055	All authors	2	included patients to the brain study|interpreted the results|contributed with the further writing of the manuscript|read and approved the final manuscript	included patients to the brain study	-	-	NO
6162005	30198055	All authors	2	included patients to the brain study|interpreted the results|contributed with the further writing of the manuscript|read and approved the final manuscript	interpreted the results	Analyzed the data	Formal analysis	YES
6162005	30198055	All authors	2	included patients to the brain study|interpreted the results|contributed with the further writing of the manuscript|read and approved the final manuscript	contributed with the further writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
6162005	30198055	All authors	2	included patients to the brain study|interpreted the results|contributed with the further writing of the manuscript|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6162005	30198055	GM	2	designed the brain study|report no competing interests	designed the brain study	Conceived and designed the experiments	Methodology	YES
6162005	30198055	GM	2	designed the brain study|report no competing interests	report no competing interests	-	-	NO
6162005	30198055	OAA	2	designed the brain study	designed the brain study	Conceived and designed the experiments	Methodology	YES
6162005	30198055	OKD	2	wrote the protocol for the present study|conducted the analyses|drafted the manuscript under|report no competing interests	wrote the protocol for the present study	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
6162005	30198055	OKD	2	wrote the protocol for the present study|conducted the analyses|drafted the manuscript under|report no competing interests	conducted the analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6162005	30198055	OKD	2	wrote the protocol for the present study|conducted the analyses|drafted the manuscript under|report no competing interests	drafted the manuscript under	Wrote the paper	Writing - Original Draft	YES
6162005	30198055	OKD	2	wrote the protocol for the present study|conducted the analyses|drafted the manuscript under|report no competing interests	report no competing interests	-	-	NO
6162005	30198055	PIF	2	wrote the protocol for the present study|conducted the analyses|supervised the drafted the manuscript under|report no competing interests	wrote the protocol for the present study	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
6162005	30198055	PIF	2	wrote the protocol for the present study|conducted the analyses|supervised the drafted the manuscript under|report no competing interests	conducted the analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6162005	30198055	PIF	2	wrote the protocol for the present study|conducted the analyses|supervised the drafted the manuscript under|report no competing interests	supervised the drafted the manuscript under	Wrote the paper	Supervision|Writing - Original Draft	YES
6162005	30198055	PIF	2	wrote the protocol for the present study|conducted the analyses|supervised the drafted the manuscript under|report no competing interests	report no competing interests	-	-	NO
6162005	30198055	Research Ethics	2	central norway, approved the brain study	central norway, approved the brain study	-	-	NO
6162005	30198055	Thomas D. Bjella	2	for preparation of data	for preparation of data	-	-	NO
6162005	30198055	UFM	2	designed the brain study	designed the brain study	Conceived and designed the experiments	Methodology	YES
5748547	29232878	C.D.	PLoS52	analyzed the data and wrote the paper	analyzed the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5748547	29232878	C.S.	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5748547	29232878	I.A.	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5748547	29232878	M.I.	PLoS52	conceived and designed the experiments|analyzed the data and wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5748547	29232878	M.I.	PLoS52	conceived and designed the experiments|analyzed the data and wrote the paper	analyzed the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5270221	28125967	GRV	2	collected the phenotype data and performed dna extraction	collected the phenotype data and performed dna extraction	Performed the experiments	Data curation|Investigation	YES
5270221	28125967	HEC	2	conceived of the study, collected the phenotype data, analyzed the phenotype and molecular information, and drafted the manuscript	conceived of the study, collected the phenotype data, analyzed the phenotype and molecular information, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
5270221	28125967	LH	2	carried out the compositional analysis of the seeds and helped draft the manuscript	carried out the compositional analysis of the seeds and helped draft the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5270221	28125967	WLR	2	carried out the compositional analysis of the seeds and helped draft the manuscript	carried out the compositional analysis of the seeds and helped draft the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5247564	28127424	Alex Chacon	7	writing, literature search	writing, literature search	Wrote the paper	Formal analysis	YES
5247564	28127424	Alexa Swaiels	7	writing, literature search. Fauzan	writing, literature search. Fauzan	Wrote the paper	Formal analysis	YES
5247564	28127424	Kurtis Childers	7	writing, literature search, review and editing	writing, literature search, review and editing	Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5247564	28127424	M Ahmed	7	writing, literature search	writing, literature search	Wrote the paper	Formal analysis	YES
5247564	28127424	Rajinder Sahi	7	editing	editing	Wrote the paper	Writing - Review & Editing	YES
5247564	28127424	Shaun Colburn	7	writing, literature search, review and editing. W	writing, literature search, review and editing. W	Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5539077	28824677	HJ	2	designed the project|performed most of the experimental work|wrote the manuscript	designed the project	Conceived and designed the experiments	Methodology	YES
5539077	28824677	HJ	2	designed the project|performed most of the experimental work|wrote the manuscript	performed most of the experimental work	Performed the experiments	Investigation	YES
5539077	28824677	HJ	2	designed the project|performed most of the experimental work|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5539077	28824677	HZ	2	extracted and saponified the pigments	extracted and saponified the pigments	Performed the experiments	Investigation	YES
5539077	28824677	YL	2	designed the project|performed most of the experimental work|wrote the manuscript	designed the project	Conceived and designed the experiments	Methodology	YES
5539077	28824677	YL	2	designed the project|performed most of the experimental work|wrote the manuscript	performed most of the experimental work	Performed the experiments	Investigation	YES
5539077	28824677	YL	2	designed the project|performed most of the experimental work|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5539077	28824677	ZC	2	designed the project	designed the project	Conceived and designed the experiments	Methodology	YES
4753845	26880241	AB	2	conceptualized the study, conducted the initial analysis, revised and approved the final manuscript	conceptualized the study, conducted the initial analysis, revised and approved the final manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Review & Editing	YES
4753845	26880241	FK	2	designed the study, conducted the initial analysis, interpreted the data and drafted the abstracts and final manuscript	designed the study, conducted the initial analysis, interpreted the data and drafted the abstracts and final manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
4753845	26880241	JB	2	collected the data, interpreted the data, revised and approved the final manuscript	collected the data, interpreted the data, revised and approved the final manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
4753845	26880241	JBL	2	conducted the final analysis and provided statistical input, revised and interpreted the final manuscript	conducted the final analysis and provided statistical input, revised and interpreted the final manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
4753845	26880241	LS	2	collected the data, interpreted the data, revised and approved the final manuscript	collected the data, interpreted the data, revised and approved the final manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
4753845	26880241	NL	2	collected the data, interpreted the data, revised and approved the final manuscript	collected the data, interpreted the data, revised and approved the final manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
4753845	26880241	SR	2	collected the data, interpreted the data, revised and approved the final manuscript	collected the data, interpreted the data, revised and approved the final manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
4753845	26880241	WV	2	collected the data, interpreted the data, revised and approved the final manuscript	collected the data, interpreted the data, revised and approved the final manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
4405362	25898024	AP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405362	25898024	AP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405362	25898024	AP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405362	25898024	AP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405362	25898024	ATL	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405362	25898024	ATL	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405362	25898024	CBL	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405362	25898024	CBL	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405362	25898024	CP	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405362	25898024	CP	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405362	25898024	DPH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405362	25898024	DPH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405362	25898024	DPH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405362	25898024	DPH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405362	25898024	DPH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405362	25898024	JH	PLoS5	Conceived and designed the experiments|Wrote the paper|Provided supplemental data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405362	25898024	JH	PLoS5	Conceived and designed the experiments|Wrote the paper|Provided supplemental data	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405362	25898024	JH	PLoS5	Conceived and designed the experiments|Wrote the paper|Provided supplemental data	Provided supplemental data	Contributed reagents/materials/analysis tools	Resources	YES
4405362	25898024	TGJ	PLoS5	Conceived and designed the experiments|Wrote the paper|Provided supplemental data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405362	25898024	TGJ	PLoS5	Conceived and designed the experiments|Wrote the paper|Provided supplemental data	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405362	25898024	TGJ	PLoS5	Conceived and designed the experiments|Wrote the paper|Provided supplemental data	Provided supplemental data	Contributed reagents/materials/analysis tools	Resources	YES
5891887	29636106	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5891887	29636106	DE	2	conceived of the study|performed statistical analysis and wrote the first draft of the manuscript|helped with the clinical interpretation of results|critically reviewed the analysis and edited the manuscript	conceived of the study	Conceived and designed the experiments	Conceptualization	YES
5891887	29636106	DE	2	conceived of the study|performed statistical analysis and wrote the first draft of the manuscript|helped with the clinical interpretation of results|critically reviewed the analysis and edited the manuscript	performed statistical analysis and wrote the first draft of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5891887	29636106	DE	2	conceived of the study|performed statistical analysis and wrote the first draft of the manuscript|helped with the clinical interpretation of results|critically reviewed the analysis and edited the manuscript	helped with the clinical interpretation of results	Analyzed the data	Formal analysis	YES
5891887	29636106	DE	2	conceived of the study|performed statistical analysis and wrote the first draft of the manuscript|helped with the clinical interpretation of results|critically reviewed the analysis and edited the manuscript	critically reviewed the analysis and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5891887	29636106	GM	2	reviewed patient files and extracted data|assisted with data management and resolving data queries	reviewed patient files and extracted data	Performed the experiments	Investigation	YES
5891887	29636106	GM	2	reviewed patient files and extracted data|assisted with data management and resolving data queries	assisted with data management and resolving data queries	Analyzed the data	Data curation	YES
5891887	29636106	IMS	2	conceived of the study|helped with the clinical interpretation of results|critically reviewed the analysis and edited the manuscript	conceived of the study	Conceived and designed the experiments	Conceptualization	YES
5891887	29636106	IMS	2	conceived of the study|helped with the clinical interpretation of results|critically reviewed the analysis and edited the manuscript	helped with the clinical interpretation of results	Analyzed the data	Formal analysis	YES
5891887	29636106	IMS	2	conceived of the study|helped with the clinical interpretation of results|critically reviewed the analysis and edited the manuscript	critically reviewed the analysis and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5891887	29636106	KH	2	reviewed patient files and extracted data|assisted with statistical analysis and literature review|critically reviewed the analysis and edited the manuscript	reviewed patient files and extracted data	Performed the experiments	Investigation	YES
5891887	29636106	KH	2	reviewed patient files and extracted data|assisted with statistical analysis and literature review|critically reviewed the analysis and edited the manuscript	assisted with statistical analysis and literature review	Analyzed the data	Formal analysis	YES
5891887	29636106	KH	2	reviewed patient files and extracted data|assisted with statistical analysis and literature review|critically reviewed the analysis and edited the manuscript	critically reviewed the analysis and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5891887	29636106	MPF	2	conceived of the study|critically reviewed the analysis and edited the manuscript	conceived of the study	Conceived and designed the experiments	Conceptualization	YES
5891887	29636106	MPF	2	conceived of the study|critically reviewed the analysis and edited the manuscript	critically reviewed the analysis and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5891887	29636106	PI	2	conceived of the study|helped with the clinical interpretation of results|critically reviewed the analysis and edited the manuscript	conceived of the study	Conceived and designed the experiments	Conceptualization	YES
5891887	29636106	PI	2	conceived of the study|helped with the clinical interpretation of results|critically reviewed the analysis and edited the manuscript	helped with the clinical interpretation of results	Analyzed the data	Formal analysis	YES
5891887	29636106	PI	2	conceived of the study|helped with the clinical interpretation of results|critically reviewed the analysis and edited the manuscript	critically reviewed the analysis and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5891887	29636106	RB	2	conceived of the study|reviewed patient files and extracted data|helped with the clinical interpretation of results|critically reviewed the analysis and edited the manuscript	conceived of the study	Conceived and designed the experiments	Conceptualization	YES
5891887	29636106	RB	2	conceived of the study|reviewed patient files and extracted data|helped with the clinical interpretation of results|critically reviewed the analysis and edited the manuscript	reviewed patient files and extracted data	Performed the experiments	Investigation	YES
5891887	29636106	RB	2	conceived of the study|reviewed patient files and extracted data|helped with the clinical interpretation of results|critically reviewed the analysis and edited the manuscript	helped with the clinical interpretation of results	Analyzed the data	Formal analysis	YES
5891887	29636106	RB	2	conceived of the study|reviewed patient files and extracted data|helped with the clinical interpretation of results|critically reviewed the analysis and edited the manuscript	critically reviewed the analysis and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5891887	29636106	SB	2	helped with the clinical interpretation of results|critically reviewed the analysis and edited the manuscript	helped with the clinical interpretation of results	Analyzed the data	Formal analysis	YES
5891887	29636106	SB	2	helped with the clinical interpretation of results|critically reviewed the analysis and edited the manuscript	critically reviewed the analysis and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
6170516	30284089	Both authors	2	indeed read and approved the final manuscript	indeed read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6170516	30284089	DV	2	also affirms that there was no editorial direction or censorship from any sponsors	also affirms that there was no editorial direction or censorship from any sponsors	-	-	NO
6170516	30284089	Doris Verwijmeren	2	reports no financial relationships with commercial interests	reports no financial relationships with commercial interests	-	-	NO
6170516	30284089	Each author	2	have contributed substantial to conception and design, and analysis and interpretation of data|have contributed substantial to drafting the article or revising it critically for important intellectual content and the final approval of the version to be published	have contributed substantial to conception and design, and analysis and interpretation of data	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Resources	YES
6170516	30284089	Each author	2	have contributed substantial to conception and design, and analysis and interpretation of data|have contributed substantial to drafting the article or revising it critically for important intellectual content and the final approval of the version to be published	have contributed substantial to drafting the article or revising it critically for important intellectual content and the final approval of the version to be published	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6170516	30284089	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5748548	29232893	H.Y.	2	conceived the study, analyzed data, and drafted the manuscript	conceived the study, analyzed data, and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
5748548	29232893	K.I.	2	participated in the design of the study and helped to draft the manuscript	participated in the design of the study and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5748548	29232893	K.T.	2	analyzed data and drafted the manuscript	analyzed data and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5748548	29232893	N.I.	2	conceived the study, collected, and analyzed data and helped to draft the manuscript	conceived the study, collected, and analyzed data and helped to draft the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
5748548	29232893	T.M.	2	participated in the design of the study and helped to draft the manuscript	participated in the design of the study and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5256676	28138387	Akira Sasaki	PLoS52	conceived the study and participated in the design and coordination of the study	conceived the study and participated in the design and coordination of the study	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
5256676	28138387	Fumitaka Endo	PLoS52	analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
5256676	28138387	Hiroyuki Nitta	PLoS52	supervised the study	supervised the study	-	Supervision	YES
5256676	28138387	Keisuke Koeda	PLoS52	supervised the study	supervised the study	-	Supervision	YES
5256676	28138387	Koki Othuka	PLoS52	supervised the study	supervised the study	-	Supervision	YES
5256676	28138387	Masafumi Konosu	PLoS52	performed the studies, data analyses, and drafted the manuscript	performed the studies, data analyses, and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5256676	28138387	Takeshi Iwaya	PLoS52	revised the article critically	revised the article critically	Wrote the paper	Writing - Review & Editing	YES
5256676	28138387	Yoshihiro Shioi	PLoS52	analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
5256676	28138387	Yuji Akiyama	PLoS52	helped in data interpretation	helped in data interpretation	Analyzed the data	Formal analysis	YES
5256676	28138387	Yusuke Kimura	PLoS52	conceived the study and participated in the design and coordination of the study	conceived the study and participated in the design and coordination of the study	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
4405363	25898204	AVG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405363	25898204	AVG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405363	25898204	AVG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405363	25898204	EDR	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405363	25898204	FLT	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405363	25898204	JSRV	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405363	25898204	MFS	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405363	25898204	MGR	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405363	25898204	MMP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4760102	26894388	AA	2	wrote the study protocol|performed the laboratory analysis	wrote the study protocol	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4760102	26894388	AA	2	wrote the study protocol|performed the laboratory analysis	performed the laboratory analysis	Performed the experiments	Investigation	YES
4760102	26894388	All authors	2	reviewed, revised and approved the final paper	reviewed, revised and approved the final paper	Wrote the paper	Writing - Review & Editing	YES
4760102	26894388	BR	2	wrote the study protocol|participated in the data collection and cleaning|performed the statistical analysis	wrote the study protocol	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4760102	26894388	BR	2	wrote the study protocol|participated in the data collection and cleaning|performed the statistical analysis	participated in the data collection and cleaning	Performed the experiments	Data curation|Investigation	YES
4760102	26894388	BR	2	wrote the study protocol|participated in the data collection and cleaning|performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
4760102	26894388	DM	2	designed the study|wrote the study protocol|participated in the data collection and cleaning|performed the statistical analysis|drafted the article	designed the study	Conceived and designed the experiments	Methodology	YES
4760102	26894388	DM	2	designed the study|wrote the study protocol|participated in the data collection and cleaning|performed the statistical analysis|drafted the article	wrote the study protocol	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4760102	26894388	DM	2	designed the study|wrote the study protocol|participated in the data collection and cleaning|performed the statistical analysis|drafted the article	participated in the data collection and cleaning	Performed the experiments	Data curation|Investigation	YES
4760102	26894388	DM	2	designed the study|wrote the study protocol|participated in the data collection and cleaning|performed the statistical analysis|drafted the article	performed the statistical analysis	Analyzed the data	Formal analysis	YES
4760102	26894388	DM	2	designed the study|wrote the study protocol|participated in the data collection and cleaning|performed the statistical analysis|drafted the article	drafted the article	Wrote the paper	Writing - Original Draft	YES
4760102	26894388	JFE	2	wrote the study protocol|drafted the article	wrote the study protocol	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4760102	26894388	JFE	2	wrote the study protocol|drafted the article	drafted the article	Wrote the paper	Writing - Original Draft	YES
4760102	26894388	MP	2	performed the laboratory analysis	performed the laboratory analysis	Performed the experiments	Investigation	YES
4760102	26894388	SM	2	participated in the data collection and cleaning	participated in the data collection and cleaning	Performed the experiments	Data curation|Investigation	YES
5874540	29301223	Conor Gilligan	PLoS52	conceived and designed the experiment|performed the experiment|wrote the paper	conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5874540	29301223	Conor Gilligan	PLoS52	conceived and designed the experiment|performed the experiment|wrote the paper	performed the experiment	Performed the experiments	Investigation	YES
5874540	29301223	Conor Gilligan	PLoS52	conceived and designed the experiment|performed the experiment|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5874540	29301223	Hayley Croft	PLoS52	conceived and designed the experiment|performed the experiment|analyzed the data|wrote the paper	conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5874540	29301223	Hayley Croft	PLoS52	conceived and designed the experiment|performed the experiment|analyzed the data|wrote the paper	performed the experiment	Performed the experiments	Investigation	YES
5874540	29301223	Hayley Croft	PLoS52	conceived and designed the experiment|performed the experiment|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5874540	29301223	Hayley Croft	PLoS52	conceived and designed the experiment|performed the experiment|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5874540	29301223	Jennifer Schneider	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5874540	29301223	Rohan Rasiah	PLoS52	conceived and designed the experiment|wrote the paper	conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5874540	29301223	Rohan Rasiah	PLoS52	conceived and designed the experiment|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5874540	29301223	Tracy Levett-Jones	PLoS52	conceived and designed the experiment|wrote the paper	conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5874540	29301223	Tracy Levett-Jones	PLoS52	conceived and designed the experiment|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5284492	28179982	Alexandra Papoudou-Bai	2	participated in the acquisition of data, analysis and interpretation of data	participated in the acquisition of data, analysis and interpretation of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5284492	28179982	Anna Batistatou	2	participated in the acquisition of data, analysis and interpretation of data	participated in the acquisition of data, analysis and interpretation of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5284492	28179982	Athina Tsili	2	participated in the acquisition of data, analysis and interpretation of data	participated in the acquisition of data, analysis and interpretation of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5284492	28179982	Georgios Glantzounis	2	conceived and designed the study|participated in the acquisition of data, analysis and interpretation of data|drafted the article and revised it critically for important intellectual content	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5284492	28179982	Georgios Glantzounis	2	conceived and designed the study|participated in the acquisition of data, analysis and interpretation of data|drafted the article and revised it critically for important intellectual content	participated in the acquisition of data, analysis and interpretation of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5284492	28179982	Georgios Glantzounis	2	conceived and designed the study|participated in the acquisition of data, analysis and interpretation of data|drafted the article and revised it critically for important intellectual content	drafted the article and revised it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5284492	28179982	Georgios K. Georgiou	2	conceived and designed the study|participated in the acquisition of data, analysis and interpretation of data|drafted the article and revised it critically for important intellectual content	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5284492	28179982	Georgios K. Georgiou	2	conceived and designed the study|participated in the acquisition of data, analysis and interpretation of data|drafted the article and revised it critically for important intellectual content	participated in the acquisition of data, analysis and interpretation of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5284492	28179982	Georgios K. Georgiou	2	conceived and designed the study|participated in the acquisition of data, analysis and interpretation of data|drafted the article and revised it critically for important intellectual content	drafted the article and revised it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5284492	28179982	Georgios Papadopoulos	2	participated in the acquisition of data, analysis and interpretation of data	participated in the acquisition of data, analysis and interpretation of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5284492	28179982	Michalis Fatouros	2	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5539086	28824666	BL	2	carried out the study, including laboratory experiments, data analysis, and drafting the manuscript	carried out the study, including laboratory experiments, data analysis, and drafting the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5539086	28824666	CL	2	collected the weather data during the study period and participated in the fieldwork and laboratory experiments	collected the weather data during the study period and participated in the fieldwork and laboratory experiments	Performed the experiments	Investigation	YES
5539086	28824666	WL	2	was responsible for the design and implementation of the entire study	was responsible for the design and implementation of the entire study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4761690	26900032	RPS	2	wrote the first draft, contributed to the critical reading and the final version of the manuscript	wrote the first draft, contributed to the critical reading and the final version of the manuscript	Wrote the paper	Writing - Original Draft	YES
4405364	25897842	DHB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405364	25897842	DHB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405364	25897842	DHB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405364	25897842	DHB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405364	25897842	GKA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405364	25897842	GKA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405364	25897842	GKA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405364	25897842	GKA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405364	25897842	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405364	25897842	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405364	25897842	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405364	25897842	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5294718	28203369	R Casula	2	assisted in writing of article	assisted in writing of article	Wrote the paper	Writing - Original Draft	YES
5294718	28203369	T Athanasiou	2	assisted in writing of article	assisted in writing of article	Wrote the paper	Writing - Original Draft	YES
5874541	29301226	Shaun Phillips	2	contributed to this research project by conceiving and designing the research, analyzing the data, and editing the manuscript	contributed to this research project by conceiving and designing the research, analyzing the data, and editing the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Methodology|Resources|Writing - Review & Editing	YES
5874541	29301226	Whitney Kiel	2	contributed to this research project by conceiving and designing the research, performing the research, analyzing the data, and writing and editing the manuscript	contributed to this research project by conceiving and designing the research, performing the research, analyzing the data, and writing and editing the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5278576	28132643	AE	2	curated candidate gene lists that facilitated comparisons of immune gene content	curated candidate gene lists that facilitated comparisons of immune gene content	Analyzed the data	Data curation	YES
5278576	28132643	MJS	2	conceived, developed, and supervised the project in addition to contributing to drafting the manuscript	conceived, developed, and supervised the project in addition to contributing to drafting the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Supervision|Writing - Original Draft	YES
5278576	28132643	MSS	2	conceived, developed, and supervised the project in addition to contributing to drafting the manuscript	conceived, developed, and supervised the project in addition to contributing to drafting the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Supervision|Writing - Original Draft	YES
5278576	28132643	NJM	2	conducted go analyses, sequence alignment, tests of positive selection and drafted the majority of the manuscript	conducted go analyses, sequence alignment, tests of positive selection and drafted the majority of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5278576	28132643	PPB	2	conducted rna extractions and library preparation for sequencing	conducted rna extractions and library preparation for sequencing	Performed the experiments	Investigation	YES
5278576	28132643	SMB	2	conducted rna extractions and library preparation for sequencing	conducted rna extractions and library preparation for sequencing	Performed the experiments	Investigation	YES
5278576	28132643	VPR	2	conducted transcriptome assembly and annotation and performed some of the comparative analysis	conducted transcriptome assembly and annotation and performed some of the comparative analysis	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
6195496	30341458	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6195496	30341458	EJR	2	contributed to the design and study protocol	contributed to the design and study protocol	Conceived and designed the experiments	Methodology	YES
6195496	30341458	JWR	2	drafted this paper and it was modified by all authors|contributed to the design and study protocol	drafted this paper and it was modified by all authors	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6195496	30341458	JWR	2	drafted this paper and it was modified by all authors|contributed to the design and study protocol	contributed to the design and study protocol	Conceived and designed the experiments	Methodology	YES
6195496	30341458	RWK	2	conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
6195496	30341458	WAN	2	conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5539092	28824670	AA	PLoS52	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5539092	28824670	BX	PLoS52	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5539092	28824670	CM	PLoS52	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5539092	28824670	JZ	PLoS52	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5539092	28824670	NZ	PLoS52	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5539092	28824670	SW	PLoS52	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5539092	28824670	TH	PLoS52	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5539092	28824670	XC	PLoS52	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5539092	28824670	YH	PLoS52	designed the experiments|performed the experiments and analyzed the data|wrote the paper	designed the experiments	Conceived and designed the experiments	Methodology	YES
5539092	28824670	YH	PLoS52	designed the experiments|performed the experiments and analyzed the data|wrote the paper	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5539092	28824670	YH	PLoS52	designed the experiments|performed the experiments and analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5539092	28824670	YR	PLoS52	proposed the present study|designed the experiments|wrote the paper	proposed the present study	Conceived and designed the experiments	Conceptualization	YES
5539092	28824670	YR	PLoS52	proposed the present study|designed the experiments|wrote the paper	designed the experiments	Conceived and designed the experiments	Methodology	YES
5539092	28824670	YR	PLoS52	proposed the present study|designed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5539092	28824670	ZX	PLoS52	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5539092	28824670	ZZ	PLoS52	proposed the present study|designed the experiments|wrote the paper	proposed the present study	Conceived and designed the experiments	Conceptualization	YES
5539092	28824670	ZZ	PLoS52	proposed the present study|designed the experiments|wrote the paper	designed the experiments	Conceived and designed the experiments	Methodology	YES
5539092	28824670	ZZ	PLoS52	proposed the present study|designed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5539092	28824670	ZeZ	PLoS52	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5902836	29661246	AC	2	were all involved in development of the datasets used and all contributed to interpretation of the results of statistical analyses in the context of existing scientific literature	were all involved in development of the datasets used and all contributed to interpretation of the results of statistical analyses in the context of existing scientific literature	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5902836	29661246	AP	2	were all involved in development of the datasets used and all contributed to interpretation of the results of statistical analyses in the context of existing scientific literature	were all involved in development of the datasets used and all contributed to interpretation of the results of statistical analyses in the context of existing scientific literature	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5902836	29661246	AT	2	assisting in data preparation and processing	assisting in data preparation and processing	Analyzed the data	Data curation	YES
5902836	29661246	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5902836	29661246	CO	2	were all involved in development of the datasets used and all contributed to interpretation of the results of statistical analyses in the context of existing scientific literature	were all involved in development of the datasets used and all contributed to interpretation of the results of statistical analyses in the context of existing scientific literature	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5902836	29661246	CS	2	were all involved in development of the datasets used and all contributed to interpretation of the results of statistical analyses in the context of existing scientific literature	were all involved in development of the datasets used and all contributed to interpretation of the results of statistical analyses in the context of existing scientific literature	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5902836	29661246	DA	2	were all involved in development of the datasets used and all contributed to interpretation of the results of statistical analyses in the context of existing scientific literature	were all involved in development of the datasets used and all contributed to interpretation of the results of statistical analyses in the context of existing scientific literature	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5902836	29661246	FM	2	were all involved in development of the datasets used and all contributed to interpretation of the results of statistical analyses in the context of existing scientific literature	were all involved in development of the datasets used and all contributed to interpretation of the results of statistical analyses in the context of existing scientific literature	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5902836	29661246	MREC	2	approvals, which waived the requirement for individual patient consent	approvals, which waived the requirement for individual patient consent	-	-	NO
5902836	29661246	OTS	2	wrote the first draft of the manuscript, with all other authors providing revisions	wrote the first draft of the manuscript, with all other authors providing revisions	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5902836	29661246	PC	2	wrote the first draft of the manuscript, with all other authors providing revisions	wrote the first draft of the manuscript, with all other authors providing revisions	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5902836	29661246	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
4168650	25246993	All authors	2	listed made substantial contributions to the final revision of the manuscript	listed made substantial contributions to the final revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4168650	25246993	CKa	2	collected the data, performed dexa and strength measurements, analysed data and wrote parts of the manuscript	collected the data, performed dexa and strength measurements, analysed data and wrote parts of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4168650	25246993	CKr	2	collected the data, performed dexa and strength measurements, analysed data and wrote parts of the manuscript	collected the data, performed dexa and strength measurements, analysed data and wrote parts of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4168650	25246993	RS	2	designed the study, supervised the measurements and the study and wrote parts of the manuscript	designed the study, supervised the measurements and the study and wrote parts of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Supervision|Writing - Original Draft	YES
4168650	25246993	SF	2	did statistics	did statistics	Analyzed the data	Formal analysis	YES
4168650	25246993	TL	2	developed the leg press, analysed data, did statistics, wrote parts of the manuscript and drafted the manuscript	developed the leg press, analysed data, did statistics, wrote parts of the manuscript and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4168650	25246993	WM	2	revised the manuscript critically for important intellectual content made contributions to conception and design of the study	revised the manuscript critically for important intellectual content made contributions to conception and design of the study	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
4168650	25246993	WS	2	revised the manuscript critically for important intellectual content made contributions to conception and design of the study	revised the manuscript critically for important intellectual content made contributions to conception and design of the study	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
4761692	26900031	AT	2	participated in the literature search, and wrote the manuscript	participated in the literature search, and wrote the manuscript	Wrote the paper	Formal analysis|Writing - Original Draft	YES
4761692	26900031	CG	2	participated in the literature search, and wrote the manuscript	participated in the literature search, and wrote the manuscript	Wrote the paper	Formal analysis|Writing - Original Draft	YES
4761692	26900031	LB	2	participated in the literature search, and wrote the manuscript	participated in the literature search, and wrote the manuscript	Wrote the paper	Formal analysis|Writing - Original Draft	YES
4761692	26900031	SGW	2	participated in the literature search, and wrote the manuscript	participated in the literature search, and wrote the manuscript	Wrote the paper	Formal analysis|Writing - Original Draft	YES
5295619	28203370	All authors	2	contributed to the conception of the manuscript and to drafting or critically revising the manuscript	contributed to the conception of the manuscript and to drafting or critically revising the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
5874542	29300350	A.J.B.	2	contributed to study design, data collection, and intellectual content of the manuscript	contributed to study design, data collection, and intellectual content of the manuscript	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources	YES
5874542	29300350	C.H.	2	contributed to study design and literature review and helped review the manuscript	contributed to study design and literature review and helped review the manuscript	Conceived and designed the experiments|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
5874542	29300350	E.K.M.	2	contributed to study design and literature review and helped review the manuscript	contributed to study design and literature review and helped review the manuscript	Conceived and designed the experiments|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
5874542	29300350	J.A.K.	2	contributed to study design and literature review and helped review the manuscript	contributed to study design and literature review and helped review the manuscript	Conceived and designed the experiments|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
5874542	29300350	P.B.J.	2	conceptualized the study, contributed to its design, data collection, analyzed and interpreted the data, and wrote the draft manuscript	conceptualized the study, contributed to its design, data collection, analyzed and interpreted the data, and wrote the draft manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
5874542	29300350	S.Q.J.	2	contributed to study design as well as data analysis and interpretation and substantially contributed to the intellectual content of the manuscript	contributed to study design as well as data analysis and interpretation and substantially contributed to the intellectual content of the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Methodology|Resources	YES
4405365	25897839	CCG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405365	25897839	CCG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405365	25897839	CCG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405365	25897839	CLW	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4405365	25897839	CM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405365	25897839	DW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405365	25897839	DW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405365	25897839	DW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405365	25897839	DW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405365	25897839	RJR	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405365	25897839	RJR	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405365	25897839	RT-L	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405365	25897839	SL-O	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5282643	28137254	A-M.D.	PLoS52	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5282643	28137254	A.L.	PLoS52	performed experiments|analyzed the data|conceived and supervised the study	performed experiments	Performed the experiments	Investigation	YES
5282643	28137254	A.L.	PLoS52	performed experiments|analyzed the data|conceived and supervised the study	analyzed the data	Analyzed the data	Formal analysis	YES
5282643	28137254	A.L.	PLoS52	performed experiments|analyzed the data|conceived and supervised the study	conceived and supervised the study	Conceived and designed the experiments	Conceptualization|Supervision	YES
5282643	28137254	D.L.	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5282643	28137254	D.T.	PLoS52	conceived and supervised the study	conceived and supervised the study	Conceived and designed the experiments	Conceptualization|Supervision	YES
5282643	28137254	F.B.	PLoS52	conceived and supervised the study	conceived and supervised the study	Conceived and designed the experiments	Conceptualization|Supervision	YES
5282643	28137254	F.J.	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5282643	28137254	L.A.	PLoS52	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5282643	28137254	M.A.	PLoS52	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5282643	28137254	M.B.	PLoS52	performed experiments|analyzed the data	performed experiments	Performed the experiments	Investigation	YES
5282643	28137254	M.B.	PLoS52	performed experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5282643	28137254	M.G.	PLoS52	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5282643	28137254	M.M.	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5539094	28824659	AM-C	2	assisted with qpcr and performed bioinformatics analysis of microarray results	assisted with qpcr and performed bioinformatics analysis of microarray results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5539094	28824659	AP	2	identified issues with previously published bak1 lines, produced and characterized the untagged bak1 transgenic plants in bak1-4 and produced the results shown in figure	identified issues with previously published bak1 lines, produced and characterized the untagged bak1 transgenic plants in bak1-4 and produced the results shown in figure	Performed the experiments	Investigation|Visualization	YES
5539094	28824659	BS	2	initiated the generation of 5 bak1-4 /bak1 plants and performed initial experiments in the cz lab	initiated the generation of 5 bak1-4 /bak1 plants and performed initial experiments in the cz lab	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5539094	28824659	CZ	2	conceived the study and oversaw research efforts|prior to approval by all authors	conceived the study and oversaw research efforts	Conceived and designed the experiments	Conceptualization|Supervision	YES
5539094	28824659	CZ	2	conceived the study and oversaw research efforts|prior to approval by all authors	prior to approval by all authors	-	-	NO
5539094	28824659	JL	2	performed the pst dc3000 hrpa inoculation experiment in - figure	performed the pst dc3000 hrpa inoculation experiment in - figure	Performed the experiments	Investigation|Visualization	YES
5539094	28824659	SH	2	conceived the study and oversaw research efforts|prior to approval by all authors	conceived the study and oversaw research efforts	Conceived and designed the experiments	Conceptualization|Supervision	YES
5539094	28824659	SH	2	conceived the study and oversaw research efforts|prior to approval by all authors	prior to approval by all authors	-	-	NO
5539094	28824659	SK	2	performed preliminary experiments that laid the foundation for this work	performed preliminary experiments that laid the foundation for this work	Performed the experiments	Investigation	YES
5539094	28824659	SS	2	assisted with qpcr and performed bioinformatics analysis of microarray results	assisted with qpcr and performed bioinformatics analysis of microarray results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5539094	28824659	VS	2	performed the pst dc3000 hrpa inoculation experiment in - figure	performed the pst dc3000 hrpa inoculation experiment in - figure	Performed the experiments	Investigation|Visualization	YES
5539094	28824659	YZ	2	performed the pst dc3000 hrpa inoculation experiment in - figure	performed the pst dc3000 hrpa inoculation experiment in - figure	Performed the experiments	Investigation|Visualization	YES
4762222	26902392	B. All	2	authors contributed to the study design, data interpretation and final revisions to the text	authors contributed to the study design, data interpretation and final revisions to the text	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
4762222	26902392	GH	2	conceptualized the study	conceptualized the study	Conceived and designed the experiments	Conceptualization	YES
6218397	30397833	All authors	2	contributed to the final manuscript|read and approved the final manuscript	contributed to the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6218397	30397833	All authors	2	contributed to the final manuscript|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6218397	30397833	BJR	2	designed the study and contributed to the data collection, data analysis, and writing of the manuscript	designed the study and contributed to the data collection, data analysis, and writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
6218397	30397833	EFM	2	designed the study, contributed to the data collection, managed the analysis and wrote the first draft of the manuscript	designed the study, contributed to the data collection, managed the analysis and wrote the first draft of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
6218397	30397833	EJR	2	contributed to the study conception and critical revision of the manuscript	contributed to the study conception and critical revision of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
6218397	30397833	JFGB	2	contributed to the study design and critical revision of the manuscript	contributed to the study design and critical revision of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
6218397	30397833	RWK	2	contributed to the study design, acquisition of data, and critical revision of the manuscript	contributed to the study design, acquisition of data, and critical revision of the manuscript	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Methodology|Resources|Writing - Review & Editing	YES
6218397	30397833	The authors	2	declare that they have no competing interests|received no financial support for the research	declare that they have no competing interests	-	-	NO
6218397	30397833	The authors	2	declare that they have no competing interests|received no financial support for the research	received no financial support for the research	-	Funding acquisition	YES
5302133	28217302	Amit Shah	7	Design, Data collection, Analysis, Critical review of manuscript	Design, Data collection, Analysis, Critical review of manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
5302133	28217302	Ankur Khajuria	7	Design, Analysis, Drafting, Critical review of manuscript	Design, Analysis, Drafting, Critical review of manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5302133	28217302	Arun Khajuria	7	Conception and Design, Data collection, Analysis, Drafting, Critical review of manuscript	Conception and Design, Data collection, Analysis, Drafting, Critical review of manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5302133	28217302	Rajesh Botchu	7	Conception and Design, Analysis, Critical review of manuscript	Conception and Design, Analysis, Critical review of manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5874543	29316609	Chelsea Phillips Renfro	2	developed and implemented the communication strategy|analyzed data|wrote the manuscript	developed and implemented the communication strategy	Performed the experiments	Investigation	YES
5874543	29316609	Chelsea Phillips Renfro	2	developed and implemented the communication strategy|analyzed data|wrote the manuscript	analyzed data	Analyzed the data	Formal analysis	YES
5874543	29316609	Chelsea Phillips Renfro	2	developed and implemented the communication strategy|analyzed data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5874543	29316609	Stefanie Ferreri	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5874543	29316609	Stephanie Foley	2	developed and implemented the communication strategy	developed and implemented the communication strategy	Performed the experiments	Investigation	YES
5874543	29316609	Tiffany Graham Barber	2	developed and implemented the communication strategy	developed and implemented the communication strategy	Performed the experiments	Investigation	YES
4405367	25897752	DBC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405367	25897752	EC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405367	25897752	JDH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405367	25897752	JGL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405367	25897752	JGL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405367	25897752	JGL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405367	25897752	JM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405367	25897752	JM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405367	25897752	JM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405367	25897752	JM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405367	25897752	JP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4405367	25897752	JP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405367	25897752	LD	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4405367	25897752	LD	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4405367	25897752	MABE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405367	25897752	MABE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405367	25897752	MABE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405367	25897752	MABE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405367	25897752	MW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405367	25897752	MW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405367	25897752	MW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405367	25897752	MW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405367	25897752	SG	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4405367	25897752	SG	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5991469	29880001	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5991469	29880001	CP	2	supervised study design and data collection|provided inputs to the manuscript	supervised study design and data collection	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Supervision	YES
5991469	29880001	CP	2	supervised study design and data collection|provided inputs to the manuscript	provided inputs to the manuscript	-	-	NO
5991469	29880001	EG	2	provided inputs to the manuscript	provided inputs to the manuscript	-	-	NO
5991469	29880001	MT	2	provided inputs to the manuscript	provided inputs to the manuscript	-	-	NO
5991469	29880001	SA	2	designed the study, collected the data, performed the analyses, interpreted the findings and developed the manuscript	designed the study, collected the data, performed the analyses, interpreted the findings and developed the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5991469	29880001	SME	2	supervised study design and data collection|supported quantitative data analysis|provided inputs to the manuscript	supervised study design and data collection	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Supervision	YES
5991469	29880001	SME	2	supervised study design and data collection|supported quantitative data analysis|provided inputs to the manuscript	supported quantitative data analysis	Analyzed the data	Formal analysis	YES
5991469	29880001	SME	2	supervised study design and data collection|supported quantitative data analysis|provided inputs to the manuscript	provided inputs to the manuscript	-	-	NO
5539120	28824667	FC	2	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5539120	28824667	JL	2	performed the experiments and analyzed the data|wrote the manuscript	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5539120	28824667	JL	2	performed the experiments and analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5539120	28824667	JW	2	conceived the project, designed the research and revised the paper	conceived the project, designed the research and revised the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
5539120	28824667	JZ	2	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5539120	28824667	SZ	2	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5539120	28824667	WY	2	conceived the project, designed the research and revised the paper	conceived the project, designed the research and revised the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
5539120	28824667	XW	2	wrote the manuscript|conceived the project, designed the research and revised the paper	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5539120	28824667	XW	2	wrote the manuscript|conceived the project, designed the research and revised the paper	conceived the project, designed the research and revised the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
5539120	28824667	ZL	2	performed the experiments and analyzed the data|wrote the manuscript	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5539120	28824667	ZL	2	performed the experiments and analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6230336	30415424	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6230336	30415424	PI	2	overall study design, interpretation of data, securing funding, writing of the manuscript	overall study design, interpretation of data, securing funding, writing of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Funding acquisition|Methodology|Writing - Original Draft	YES
5282740	28143402	JMY	2	contributed with the design of the study, discussion and with the writing of the manuscript	contributed with the design of the study, discussion and with the writing of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5282740	28143402	JPL	2	contributed with the design of the study and discussion	contributed with the design of the study and discussion	Conceived and designed the experiments	Methodology	YES
5282740	28143402	KC	2	contributed with the data analysis and discussion	contributed with the data analysis and discussion	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5282740	28143402	RB	2	contributed with the design of the study, performed the data analysis, discussion and wrote the manuscript	contributed with the design of the study, performed the data analysis, discussion and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Original Draft	YES
5282740	28143402	RF	2	contributed with the data preparation, scripts for data analysis and preparation of graphs	contributed with the data preparation, scripts for data analysis and preparation of graphs	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources|Software	YES
4770824	26928811	CC	2	wrote the first draft of the manuscript, and all authors approved the final draft	wrote the first draft of the manuscript, and all authors approved the final draft	Wrote the paper	Writing - Original Draft	YES
4405368	25897783	FGN	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Critically revised the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4405368	25897783	FGN	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Critically revised the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405368	25897783	FGN	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Critically revised the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405368	25897783	FGN	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Critically revised the manuscript	Critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4405368	25897783	FLR	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405368	25897783	JRR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405368	25897783	JRR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405368	25897783	JRR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405368	25897783	JRR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405368	25897783	JRR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405368	25897783	LAD	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4405368	25897783	LAD	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405368	25897783	MJVS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4405368	25897783	MJVS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
6262066	30488295	Both authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6262066	30488295	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5874544	29316686	Constantin Mircioiu	2	provided data and information, and helped with the revisions of the manuscript|wrote the manuscript	provided data and information, and helped with the revisions of the manuscript	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Review & Editing	YES
5874544	29316686	Constantin Mircioiu	2	provided data and information, and helped with the revisions of the manuscript|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5874544	29316686	Cristina Rais	2	provided data and information, and helped with the revisions of the manuscript	provided data and information, and helped with the revisions of the manuscript	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Review & Editing	YES
5874544	29316686	Jeffrey Atkinson	2	wrote the manuscript|coordinated the revisions	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5874544	29316686	Jeffrey Atkinson	2	wrote the manuscript|coordinated the revisions	coordinated the revisions	Wrote the paper	Project administration|Writing - Review & Editing	YES
5874544	29316686	Roxana Sandulovici	2	provided data and information, and helped with the revisions of the manuscript	provided data and information, and helped with the revisions of the manuscript	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Review & Editing	YES
5302139	28217301	Atsuko Tsutsui	2	contributed to the study design, data collection, data analysis, data interpretation, and writing of the paper	contributed to the study design, data collection, data analysis, data interpretation, and writing of the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
5302139	28217301	Hirohisa Miura	2	contributed to the study design, data collection, data analysis, data interpretation, and writing of the paper	contributed to the study design, data collection, data analysis, data interpretation, and writing of the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
5302139	28217301	Kazushige Hayakawa	2	contributed to the study design, data collection, data analysis, data interpretation, and writing of the paper	contributed to the study design, data collection, data analysis, data interpretation, and writing of the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
5302139	28217301	Masahiko Watanabe	2	contributed to the study design, data collection, data analysis, data interpretation, and writing of the paper	contributed to the study design, data collection, data analysis, data interpretation, and writing of the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
5302139	28217301	Masanori Naito	2	contributed to the study design, data collection, data analysis, data interpretation, and writing of the paper	contributed to the study design, data collection, data analysis, data interpretation, and writing of the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
5302139	28217301	Takahiro Yamanashi	2	contributed to the study design, data collection, data analysis, data interpretation, and writing of the paper	contributed to the study design, data collection, data analysis, data interpretation, and writing of the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
5302139	28217301	Takatoshi Nakamura	2	contributed to the study design, data collection, data analysis, data interpretation, and writing of the paper	contributed to the study design, data collection, data analysis, data interpretation, and writing of the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
5302139	28217301	Takeo Sato	2	contributed to the study design, data collection, data analysis, data interpretation, and writing of the paper	contributed to the study design, data collection, data analysis, data interpretation, and writing of the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
5302139	28217301	The authors	2	contributed to the study design, data collection, data analysis, data interpretation, and writing of the paper	contributed to the study design, data collection, data analysis, data interpretation, and writing of the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
5302139	28217301	Yoko Takayama	2	contributed to the study design, data collection, data analysis, data interpretation, and writing of the paper	contributed to the study design, data collection, data analysis, data interpretation, and writing of the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
5302139	28217301	all the authors	2	mentioned above	mentioned above	-	-	NO
6158807	30261902	AA	2	reviewed and edited the manuscript|oversaw the participants|lead the study	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
6158807	30261902	AA	2	reviewed and edited the manuscript|oversaw the participants|lead the study	oversaw the participants	-	Supervision	YES
6158807	30261902	AA	2	reviewed and edited the manuscript|oversaw the participants|lead the study	lead the study	-	-	NO
6158807	30261902	AH	2	oversaw the participants	oversaw the participants	-	Supervision	YES
6158807	30261902	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6158807	30261902	KR	2	lead the study	lead the study	-	-	NO
6158807	30261902	SG	2	oversaw the participants	oversaw the participants	-	Supervision	YES
6158807	30261902	SK	2	reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
6158807	30261902	TA	2	performed statistical analysis	performed statistical analysis	Analyzed the data	Formal analysis	YES
6158807	30261902	WMH	2	drafted the manuscript|oversaw the participants	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
6158807	30261902	WMH	2	drafted the manuscript|oversaw the participants	oversaw the participants	-	Supervision	YES
5539123	28824669	BS	2	conceived the original research approach and designed the experiments	conceived the original research approach and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5539123	28824669	CM	2	conceived the original research approach and designed the experiments	conceived the original research approach and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5539123	28824669	DT	2	conceived the original research approach and designed the experiments|performed the in-vitro pollinations|produced genetic maps|with contributions from all authors	conceived the original research approach and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5539123	28824669	DT	2	conceived the original research approach and designed the experiments|performed the in-vitro pollinations|produced genetic maps|with contributions from all authors	performed the in-vitro pollinations	Performed the experiments	Investigation	YES
5539123	28824669	DT	2	conceived the original research approach and designed the experiments|performed the in-vitro pollinations|produced genetic maps|with contributions from all authors	produced genetic maps	Performed the experiments	Investigation	YES
5539123	28824669	DT	2	conceived the original research approach and designed the experiments|performed the in-vitro pollinations|produced genetic maps|with contributions from all authors	with contributions from all authors	-	-	NO
5539123	28824669	MH	2	developed the lolium snp chip array|produced genetic maps	developed the lolium snp chip array	Performed the experiments	Investigation	YES
5539123	28824669	MH	2	developed the lolium snp chip array|produced genetic maps	produced genetic maps	Performed the experiments	Investigation	YES
5539123	28824669	SY	2	conceived the original research approach and designed the experiments	conceived the original research approach and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5539123	28824669	TB	2	developed the lolium snp chip array|produced genetic maps	developed the lolium snp chip array	Performed the experiments	Investigation	YES
5539123	28824669	TB	2	developed the lolium snp chip array|produced genetic maps	produced genetic maps	Performed the experiments	Investigation	YES
4770825	26928810	AJS	2	were the key developers of the mathematical model used in this analysis|developed the time-varying methodology, under the|produced all the results and figures and was the lead writer of the manuscript|collected the data to inform the mathematical model and developed the original analysis and report from which this methodology is built upon	were the key developers of the mathematical model used in this analysis	Performed the experiments|Analyzed the data	Formal analysis|Methodology	YES
4770825	26928810	AJS	2	were the key developers of the mathematical model used in this analysis|developed the time-varying methodology, under the|produced all the results and figures and was the lead writer of the manuscript|collected the data to inform the mathematical model and developed the original analysis and report from which this methodology is built upon	developed the time-varying methodology, under the	Performed the experiments	Methodology	YES
4770825	26928810	AJS	2	were the key developers of the mathematical model used in this analysis|developed the time-varying methodology, under the|produced all the results and figures and was the lead writer of the manuscript|collected the data to inform the mathematical model and developed the original analysis and report from which this methodology is built upon	produced all the results and figures and was the lead writer of the manuscript	Wrote the paper	Visualization|Writing - Original Draft	YES
4770825	26928810	AJS	2	were the key developers of the mathematical model used in this analysis|developed the time-varying methodology, under the|produced all the results and figures and was the lead writer of the manuscript|collected the data to inform the mathematical model and developed the original analysis and report from which this methodology is built upon	collected the data to inform the mathematical model and developed the original analysis and report from which this methodology is built upon	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
4770825	26928810	All authors	2	reviewed and contributed to the final manuscript	reviewed and contributed to the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4770825	26928810	CB	2	collected the data to inform the mathematical model and developed the original analysis and report from which this methodology is built upon	collected the data to inform the mathematical model and developed the original analysis and report from which this methodology is built upon	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
4770825	26928810	CCK	2	were the key developers of the mathematical model used in this analysis	were the key developers of the mathematical model used in this analysis	Performed the experiments|Analyzed the data	Formal analysis|Methodology	YES
4770825	26928810	DWP	2	were the key developers of the mathematical model used in this analysis|supervised the under the	were the key developers of the mathematical model used in this analysis	Performed the experiments|Analyzed the data	Formal analysis|Methodology	YES
4770825	26928810	DWP	2	were the key developers of the mathematical model used in this analysis|supervised the under the	supervised the under the	-	Supervision	YES
4770825	26928810	EM	2	collected the data to inform the mathematical model and developed the original analysis and report from which this methodology is built upon	collected the data to inform the mathematical model and developed the original analysis and report from which this methodology is built upon	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
4770825	26928810	MG	2	collected the data to inform the mathematical model and developed the original analysis and report from which this methodology is built upon	collected the data to inform the mathematical model and developed the original analysis and report from which this methodology is built upon	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
4770825	26928810	NF	2	collected the data to inform the mathematical model and developed the original analysis and report from which this methodology is built upon	collected the data to inform the mathematical model and developed the original analysis and report from which this methodology is built upon	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
4770825	26928810	RMS	2	were the key developers of the mathematical model used in this analysis	were the key developers of the mathematical model used in this analysis	Performed the experiments|Analyzed the data	Formal analysis|Methodology	YES
4770825	26928810	RTG	2	were the key developers of the mathematical model used in this analysis|supervised the under the|collected the data to inform the mathematical model and developed the original analysis and report from which this methodology is built upon	were the key developers of the mathematical model used in this analysis	Performed the experiments|Analyzed the data	Formal analysis|Methodology	YES
4770825	26928810	RTG	2	were the key developers of the mathematical model used in this analysis|supervised the under the|collected the data to inform the mathematical model and developed the original analysis and report from which this methodology is built upon	supervised the under the	-	Supervision	YES
4770825	26928810	RTG	2	were the key developers of the mathematical model used in this analysis|supervised the under the|collected the data to inform the mathematical model and developed the original analysis and report from which this methodology is built upon	collected the data to inform the mathematical model and developed the original analysis and report from which this methodology is built upon	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5304244	28224036	Boonying Siribumrungwong	7	data collections	data collections	Performed the experiments	Investigation	YES
5304244	28224036	Chumpon Wilasrusmee	7	study design, data collections, data analysis, writing	study design, data collections, data analysis, writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology	YES
5304244	28224036	Suthas Horsirimanont Napaphat	7	data analysis. Jakrapan Jirasiritham Ammarin Thakkinstian	data analysis. Jakrapan Jirasiritham Ammarin Thakkinstian	Analyzed the data	Formal analysis	YES
6269438	30506151	The author	2	read and approved the final manuscript|declares that there is no competing interests	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6269438	30506151	The author	2	read and approved the final manuscript|declares that there is no competing interests	declares that there is no competing interests	-	-	NO
5282741	28143409	CC	2	developed experimental design, performed analyses and wrote the manuscript	developed experimental design, performed analyses and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5282741	28143409	CS	2	prepared and sequenced rnas, respectively	prepared and sequenced rnas, respectively	Performed the experiments	Investigation	YES
5282741	28143409	GG	2	prepared and sequenced rnas, respectively	prepared and sequenced rnas, respectively	Performed the experiments	Investigation	YES
5282741	28143409	GJB	2	contributed to experimental design and manuscript preparation	contributed to experimental design and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5282741	28143409	PS	2	contributed to experimental design and manuscript preparation	contributed to experimental design and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5282741	28143409	RS	2	developed experimental design, performed analyses and wrote the manuscript	developed experimental design, performed analyses and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4405369	25898362	AB	PLoS5	Collected data	Collected data	Performed the experiments	Investigation	YES
4405369	25898362	AK	PLoS5	Collected data	Collected data	Performed the experiments	Investigation	YES
4405369	25898362	DKR	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4405369	25898362	DKR	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405369	25898362	DN	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405369	25898362	HC	PLoS5	Collected data	Collected data	Performed the experiments	Investigation	YES
4405369	25898362	KCA	PLoS5	Collected data	Collected data	Performed the experiments	Investigation	YES
4405369	25898362	NA	PLoS5	Collected data	Collected data	Performed the experiments	Investigation	YES
4405369	25898362	NB	PLoS5	Assisted in developing the protocol|Collected data	Assisted in developing the protocol	Conceived and designed the experiments	Methodology	YES
4405369	25898362	NB	PLoS5	Assisted in developing the protocol|Collected data	Collected data	Performed the experiments	Investigation	YES
4405369	25898362	NW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Collected data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405369	25898362	NW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Collected data	Analyzed the data	Analyzed the data	Formal analysis	YES
4405369	25898362	NW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Collected data	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405369	25898362	NW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Collected data	Collected data	Performed the experiments	Investigation	YES
4405369	25898362	RA	PLoS5	Assisted in developing the protocol|Collected data	Assisted in developing the protocol	Conceived and designed the experiments	Methodology	YES
4405369	25898362	RA	PLoS5	Assisted in developing the protocol|Collected data	Collected data	Performed the experiments	Investigation	YES
4405369	25898362	RS	PLoS5	Collected data	Collected data	Performed the experiments	Investigation	YES
4405369	25898362	RT	PLoS5	Assisted in developing the protocol|Collected data	Assisted in developing the protocol	Conceived and designed the experiments	Methodology	YES
4405369	25898362	RT	PLoS5	Assisted in developing the protocol|Collected data	Collected data	Performed the experiments	Investigation	YES
4405369	25898362	S. Ramji	PLoS5	Conceived and designed the experiments|Collected data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405369	25898362	S. Ramji	PLoS5	Conceived and designed the experiments|Collected data	Collected data	Performed the experiments	Investigation	YES
4405369	25898362	S. Rath	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405369	25898362	S. Rath	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405369	25898362	S. Rath	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405369	25898362	S. Rath	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405369	25898362	S. Raza	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405369	25898362	S. Saini	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405369	25898362	S. Sopory	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405369	25898362	SA	PLoS5	Collected data	Collected data	Performed the experiments	Investigation	YES
4405369	25898362	SB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405369	25898362	SB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405369	25898362	SB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405369	25898362	UCMN	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405369	25898362	UCMN	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4405369	25898362	UM	PLoS5	Collected data	Collected data	Performed the experiments	Investigation	YES
4405369	25898362	VB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405369	25898362	VB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405369	25898362	VB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405369	25898362	VB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405369	25898362	VKP	PLoS5	Collected data	Collected data	Performed the experiments	Investigation	YES
4778406	26942721	AG	2	analyzed the data and revised the manuscript	analyzed the data and revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4778406	26942721	CB	2	contributed to data collection|analyzed the data and revised the manuscript	contributed to data collection	Performed the experiments	Investigation	YES
4778406	26942721	CB	2	contributed to data collection|analyzed the data and revised the manuscript	analyzed the data and revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4778406	26942721	CF	2	designed the study|analyzed the data and revised the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
4778406	26942721	CF	2	designed the study|analyzed the data and revised the manuscript	analyzed the data and revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4778406	26942721	JK	2	analyzed the data and revised the manuscript	analyzed the data and revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4778406	26942721	JO	2	designed the study|analyzed the data and revised the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
4778406	26942721	JO	2	designed the study|analyzed the data and revised the manuscript	analyzed the data and revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4778406	26942721	MC	2	contributed to data collection|analyzed the data and revised the manuscript	contributed to data collection	Performed the experiments	Investigation	YES
4778406	26942721	MC	2	contributed to data collection|analyzed the data and revised the manuscript	analyzed the data and revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4778406	26942721	PC	2	designed the study|analyzed the data and revised the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
4778406	26942721	PC	2	designed the study|analyzed the data and revised the manuscript	analyzed the data and revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4778406	26942721	SC	2	contributed to data collection|analyzed the data and revised the manuscript	contributed to data collection	Performed the experiments	Investigation	YES
4778406	26942721	SC	2	contributed to data collection|analyzed the data and revised the manuscript	analyzed the data and revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4778406	26942721	SW	2	contributed to data collection|analyzed the data and revised the manuscript	contributed to data collection	Performed the experiments	Investigation	YES
4778406	26942721	SW	2	contributed to data collection|analyzed the data and revised the manuscript	analyzed the data and revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4778406	26942721	TR	2	contributed to data collection|analyzed the data and revised the manuscript	contributed to data collection	Performed the experiments	Investigation	YES
4778406	26942721	TR	2	contributed to data collection|analyzed the data and revised the manuscript	analyzed the data and revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
6195707	30340608	AK	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
6195707	30340608	AVR	2	conducted or contributed to the data analysis|interpreted the data	conducted or contributed to the data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6195707	30340608	AVR	2	conducted or contributed to the data analysis|interpreted the data	interpreted the data	Analyzed the data	Formal analysis	YES
6195707	30340608	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6195707	30340608	BC	2	designed the study|supervised data collection of the study|interpreted the data	designed the study	Conceived and designed the experiments	Methodology	YES
6195707	30340608	BC	2	designed the study|supervised data collection of the study|interpreted the data	supervised data collection of the study	Performed the experiments	Investigation|Supervision	YES
6195707	30340608	BC	2	designed the study|supervised data collection of the study|interpreted the data	interpreted the data	Analyzed the data	Formal analysis	YES
6195707	30340608	BJ	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
6195707	30340608	BT	2	supervised data collection of the study|abstracted the data	supervised data collection of the study	Performed the experiments	Investigation|Supervision	YES
6195707	30340608	BT	2	supervised data collection of the study|abstracted the data	abstracted the data	-	-	NO
6195707	30340608	DM	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
6195707	30340608	MJ	2	supervised data collection of the study|abstracted the data|conducted or contributed to the data analysis|interpreted the data	supervised data collection of the study	Performed the experiments	Investigation|Supervision	YES
6195707	30340608	MJ	2	supervised data collection of the study|abstracted the data|conducted or contributed to the data analysis|interpreted the data	abstracted the data	-	-	NO
6195707	30340608	MJ	2	supervised data collection of the study|abstracted the data|conducted or contributed to the data analysis|interpreted the data	conducted or contributed to the data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6195707	30340608	MJ	2	supervised data collection of the study|abstracted the data|conducted or contributed to the data analysis|interpreted the data	interpreted the data	Analyzed the data	Formal analysis	YES
6195707	30340608	MK	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
6195707	30340608	PK	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
6195707	30340608	SO	2	designed the study|supervised data collection of the study|abstracted the data|conducted or contributed to the data analysis|interpreted the data|prepared the original manuscripts	designed the study	Conceived and designed the experiments	Methodology	YES
6195707	30340608	SO	2	designed the study|supervised data collection of the study|abstracted the data|conducted or contributed to the data analysis|interpreted the data|prepared the original manuscripts	supervised data collection of the study	Performed the experiments	Investigation|Supervision	YES
6195707	30340608	SO	2	designed the study|supervised data collection of the study|abstracted the data|conducted or contributed to the data analysis|interpreted the data|prepared the original manuscripts	abstracted the data	-	-	NO
6195707	30340608	SO	2	designed the study|supervised data collection of the study|abstracted the data|conducted or contributed to the data analysis|interpreted the data|prepared the original manuscripts	conducted or contributed to the data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6195707	30340608	SO	2	designed the study|supervised data collection of the study|abstracted the data|conducted or contributed to the data analysis|interpreted the data|prepared the original manuscripts	interpreted the data	Analyzed the data	Formal analysis	YES
6195707	30340608	SO	2	designed the study|supervised data collection of the study|abstracted the data|conducted or contributed to the data analysis|interpreted the data|prepared the original manuscripts	prepared the original manuscripts	Wrote the paper	Writing - Original Draft	YES
6195707	30340608	all authors	2	contributed to subsequent revisions	contributed to subsequent revisions	Wrote the paper	Writing - Review & Editing	YES
5539139	28824672	S. All	2	the authors have commented, read and approved the final manuscript	the authors have commented, read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5310140	28224038	All	1	Data interpretation	Data interpretation	Analyzed the data	Formal analysis	YES
5310140	28224038	HT	1	Review	Review	-	-	NO
5310140	28224038	KN	1	Review	Review	-	-	NO
5310140	28224038	KT	1	Review	Review	-	-	NO
5310140	28224038	MW	1	Study design|Data collection|Data analysis/interpretation|Paper writing	Study design	Conceived and designed the experiments	Methodology	YES
5310140	28224038	MW	1	Study design|Data collection|Data analysis/interpretation|Paper writing	Data collection	Performed the experiments	Investigation	YES
5310140	28224038	MW	1	Study design|Data collection|Data analysis/interpretation|Paper writing	Data analysis/interpretation	Analyzed the data	Formal analysis	YES
5310140	28224038	MW	1	Study design|Data collection|Data analysis/interpretation|Paper writing	Paper writing	Wrote the paper	-	YES
5310140	28224038	NT	1	Data collection	Data collection	Performed the experiments	Investigation	YES
5310140	28224038	SO	1	Paper writing|Review	Paper writing	Wrote the paper	-	YES
5310140	28224038	SO	1	Paper writing|Review	Review	-	-	NO
5310140	28224038	YN	1	Data collection	Data collection	Performed the experiments	Investigation	YES
5874545	29342983	Abhijit Das	2	carried out conception and design of the study, statistical analysis, and interpretation of data	carried out conception and design of the study, statistical analysis, and interpretation of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation|Methodology	YES
5874545	29342983	Bijoy Laxmi Saha	2	carried out the data collection process and conducted the research work|wrote the manuscript	carried out the data collection process and conducted the research work	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5874545	29342983	Bijoy Laxmi Saha	2	carried out the data collection process and conducted the research work|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5874545	29342983	Kabir Choudhuri	2	carried out conception and design of the study, statistical analysis, and interpretation of data	carried out conception and design of the study, statistical analysis, and interpretation of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation|Methodology	YES
5874545	29342983	M. Shahabuddin	2	carried out conception and design of the study, statistical analysis, and interpretation of data	carried out conception and design of the study, statistical analysis, and interpretation of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation|Methodology	YES
5874545	29342983	Mohammad Mafruhi Sattar	2	carried out conception and design of the study, statistical analysis, and interpretation of data	carried out conception and design of the study, statistical analysis, and interpretation of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation|Methodology	YES
5874545	29342983	Monir Hossain	2	helped in the data collection procedure, revised the manuscript, and gave guidance to improve the quality of the final manuscript	helped in the data collection procedure, revised the manuscript, and gave guidance to improve the quality of the final manuscript	Performed the experiments|Wrote the paper	Data curation|Investigation|Supervision|Writing - Review & Editing	YES
5874545	29342983	Omar Reza Seam	2	carried out the data collection process and conducted the research work	carried out the data collection process and conducted the research work	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5874545	29342983	Palash Karmakar	2	carried out conception and design of the study, statistical analysis, and interpretation of data	carried out conception and design of the study, statistical analysis, and interpretation of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation|Methodology	YES
5874545	29342983	S. M. Naim	2	helped in the data collection procedure, revised the manuscript, and gave guidance to improve the quality of the final manuscript	helped in the data collection procedure, revised the manuscript, and gave guidance to improve the quality of the final manuscript	Performed the experiments|Wrote the paper	Data curation|Investigation|Supervision|Writing - Review & Editing	YES
5310165	28224037	Kohei Okuyama	2	established study design and wrote paper	established study design and wrote paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5310165	28224037	Masahiro Umeda	2	related and advised the treatment of this case	related and advised the treatment of this case	-	-	NO
5310165	28224037	Souichi Yanamoto	2	related and advised the treatment of this case	related and advised the treatment of this case	-	-	NO
5310165	28224037	Tomofumi Naruse	2	related and advised the treatment of this case	related and advised the treatment of this case	-	-	NO
5310165	28224037	Yuki Sakamoto	2	related and advised the treatment of this case	related and advised the treatment of this case	-	-	NO
4405373	25898273	JSX	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Collected literature and software tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405373	25898273	JSX	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Collected literature and software tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4405373	25898273	JSX	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Collected literature and software tools	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405373	25898273	JSX	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Collected literature and software tools	Collected literature and software tools	Performed the experiments|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Software	YES
4405373	25898273	QH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Collected literature and software tools	Performed the experiments	Performed the experiments	Investigation	YES
4405373	25898273	QH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Collected literature and software tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4405373	25898273	QH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Collected literature and software tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405373	25898273	QH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Collected literature and software tools	Collected literature and software tools	Performed the experiments|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Software	YES
4405373	25898273	XQD	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405373	25898273	ZGM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405373	25898273	ZYZ	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6274637	30506447	All authors	2	contributed to writing the manuscript|read and approved the final manuscript	contributed to writing the manuscript	Wrote the paper	Writing - Original Draft	YES
6274637	30506447	All authors	2	contributed to writing the manuscript|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6274637	30506447	EP	2	performed the literature search and selected relevant articles|produced the tables	performed the literature search and selected relevant articles	Performed the experiments	Formal analysis|Investigation	YES
6274637	30506447	EP	2	performed the literature search and selected relevant articles|produced the tables	produced the tables	-	-	NO
6274637	30506447	HB	2	performed the literature search and selected relevant articles	performed the literature search and selected relevant articles	Performed the experiments	Formal analysis|Investigation	YES
6274637	30506447	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
6274637	30506447	VB	2	performed the literature search and selected relevant articles	performed the literature search and selected relevant articles	Performed the experiments	Formal analysis|Investigation	YES
5282744	28137252	BFK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
5282744	28137252	BFK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5282744	28137252	BFK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5282744	28137252	BJGS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5282744	28137252	BJGS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
5282744	28137252	BJGS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5282744	28137252	BJGS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5282744	28137252	LMB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5282744	28137252	LMB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
5282744	28137252	LMB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
5282744	28137252	LMB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5282744	28137252	LMB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5282744	28137252	SRMJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5282744	28137252	SRMJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
5282744	28137252	SRMJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5282744	28137252	SRMJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5539172	28824674	GB	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5539172	28824674	MZ	PLoS52	designed the research|drafted the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
5539172	28824674	MZ	PLoS52	designed the research|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5539172	28824674	WH	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5539172	28824674	XW	PLoS52	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5539172	28824674	ZF	PLoS52	designed the research|performed the experiments|drafted the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
5539172	28824674	ZF	PLoS52	designed the research|performed the experiments|drafted the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5539172	28824674	ZF	PLoS52	designed the research|performed the experiments|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5539172	28824674	ZW	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
4195176	25320652	AR	2	assisted in clinical data collection, interpretation of results, and provided important contributions to earlier drafts of the manuscript	assisted in clinical data collection, interpretation of results, and provided important contributions to earlier drafts of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4195176	25320652	DW	2	conceptualized the study, analyzed the data, and prepared the first draft of the manuscript	conceptualized the study, analyzed the data, and prepared the first draft of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
4195176	25320652	JM	2	co-created the tool, assisted in interpretation of results and data presentation	co-created the tool, assisted in interpretation of results and data presentation	Analyzed the data	Formal analysis	YES
4195176	25320652	JV	2	assisted in clinical data collection, interpretation of results, and provided important contributions to earlier drafts of the manuscript	assisted in clinical data collection, interpretation of results, and provided important contributions to earlier drafts of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4195176	25320652	MP	2	assisted in clinical data collection, interpretation of results, and provided important contributions to earlier drafts of the manuscript	assisted in clinical data collection, interpretation of results, and provided important contributions to earlier drafts of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5874546	29337859	All authors	2	were involved in the study concept and design|participated in critical revision of the manuscript, contributed comments, and approved the final version	were involved in the study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5874546	29337859	All authors	2	were involved in the study concept and design|participated in critical revision of the manuscript, contributed comments, and approved the final version	participated in critical revision of the manuscript, contributed comments, and approved the final version	Wrote the paper	Writing - Review & Editing	YES
5874546	29337859	Bettina Pfister	2	were involved in the acquisition, analysis, and interpretation of data	were involved in the acquisition, analysis, and interpretation of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5874546	29337859	Hugo Lovheim	2	were involved in the acquisition, analysis, and interpretation of data	were involved in the acquisition, analysis, and interpretation of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5874546	29337859	Maria Gustafsson	2	were involved in the acquisition, analysis, and interpretation of data|performed the statistical analysis	were involved in the acquisition, analysis, and interpretation of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5874546	29337859	Maria Gustafsson	2	were involved in the acquisition, analysis, and interpretation of data|performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
4779330	26945343	DEK	2	critically read and revised the manuscript	critically read and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4779330	26945343	JPR	2	contributed significantly to conducting the literature review and drafted the manuscript	contributed significantly to conducting the literature review and drafted the manuscript	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
4779330	26945343	TL	2	critically read and revised the manuscript	critically read and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4779330	26945343	VM	2	contributed to reviewing the literature, constructing the figures and refining the manuscript	contributed to reviewing the literature, constructing the figures and refining the manuscript	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Visualization|Writing - Review & Editing	YES
4779330	26945343	WC	2	contributed significantly to conducting the literature review and drafted the manuscript	contributed significantly to conducting the literature review and drafted the manuscript	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
6195714	30340607	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6195714	30340607	CK	2	conceptualized the study|were responsible for the acquisition, analysis and interpretation of data|played a role in writing, editing and approving the final version	conceptualized the study	Conceived and designed the experiments	Conceptualization	YES
6195714	30340607	CK	2	conceptualized the study|were responsible for the acquisition, analysis and interpretation of data|played a role in writing, editing and approving the final version	were responsible for the acquisition, analysis and interpretation of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6195714	30340607	CK	2	conceptualized the study|were responsible for the acquisition, analysis and interpretation of data|played a role in writing, editing and approving the final version	played a role in writing, editing and approving the final version	Wrote the paper	Writing - Review & Editing	YES
6195714	30340607	EF	2	played a role in writing, editing and approving the final version	played a role in writing, editing and approving the final version	Wrote the paper	Writing - Review & Editing	YES
6195714	30340607	JB	2	were responsible for the acquisition, analysis and interpretation of data|played a role in writing, editing and approving the final version	were responsible for the acquisition, analysis and interpretation of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6195714	30340607	JB	2	were responsible for the acquisition, analysis and interpretation of data|played a role in writing, editing and approving the final version	played a role in writing, editing and approving the final version	Wrote the paper	Writing - Review & Editing	YES
6195714	30340607	KW	2	played a role in writing, editing and approving the final version	played a role in writing, editing and approving the final version	Wrote the paper	Writing - Review & Editing	YES
6195714	30340607	STI	2	outcome data in analyses such as this one	outcome data in analyses such as this one	Analyzed the data	Formal analysis	YES
6195714	30340607	TP	2	played a role in writing, editing and approving the final version	played a role in writing, editing and approving the final version	Wrote the paper	Writing - Review & Editing	YES
6195714	30340607	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5312456	28228943	J. Plummer	7	study design, writing	study design, writing	Conceived and designed the experiments|Wrote the paper	Methodology	YES
5312456	28228943	M. Reid	7	study design, data analysis	study design, data analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5312456	28228943	P. Leake	7	study design, data collection, writing	study design, data collection, writing	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology	YES
4405374	25897966	BP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405374	25897966	BP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405374	25897966	BP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405374	25897966	BP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405374	25897966	DAF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405374	25897966	DAF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405374	25897966	DAF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405374	25897966	ID	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405374	25897966	ID	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405374	25897966	ID	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405374	25897966	IT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405374	25897966	IT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405374	25897966	IT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405374	25897966	IT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405374	25897966	LM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405374	25897966	LM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4405374	25897966	LM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4405374	25897966	RB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405374	25897966	RB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405374	25897966	RB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405374	25897966	WCW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405374	25897966	WCW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405374	25897966	WCW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4484838	26176013	Elena De Falco	2	equally contributed to this work	equally contributed to this work	-	-	NO
4484838	26176013	Mariangela Peruzzi	2	equally contributed to this work	equally contributed to this work	-	-	NO
6320328	30610501	AS	2	participated in the planning and reporting of the study	participated in the planning and reporting of the study	Conceived and designed the experiments	Methodology	YES
6320328	30610501	All	2	participants gave their informed consent prior to the start of the interview	participants gave their informed consent prior to the start of the interview	Performed the experiments	Investigation	YES
6320328	30610501	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6320328	30610501	HGL	2	participated in the conceptualization, planning, analysis and reporting of the study	participated in the conceptualization, planning, analysis and reporting of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6320328	30610501	PG	2	participated in the conceptualization, planning, analysis and reporting of the study	participated in the conceptualization, planning, analysis and reporting of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6320328	30610501	SV	2	participated in the planning and reporting of the study	participated in the planning and reporting of the study	Conceived and designed the experiments	Methodology	YES
6320328	30610501	TD	2	participated in the conceptualization, planning, analysis and reporting of the study	participated in the conceptualization, planning, analysis and reporting of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6320328	30610501	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5539180	28824668	CS	2	conceived and designed the study|carried out the experiments|analyzed and interpreted the data|prepared the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5539180	28824668	CS	2	conceived and designed the study|carried out the experiments|analyzed and interpreted the data|prepared the manuscript	carried out the experiments	Performed the experiments	Investigation	YES
5539180	28824668	CS	2	conceived and designed the study|carried out the experiments|analyzed and interpreted the data|prepared the manuscript	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5539180	28824668	CS	2	conceived and designed the study|carried out the experiments|analyzed and interpreted the data|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5539180	28824668	DC	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5539180	28824668	GJ	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5539180	28824668	HC	2	provided the r	provided the r	-	-	NO
5539180	28824668	JJ	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5539180	28824668	KS	2	conceived and designed the study|carried out the experiments|analyzed and interpreted the data|prepared the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5539180	28824668	KS	2	conceived and designed the study|carried out the experiments|analyzed and interpreted the data|prepared the manuscript	carried out the experiments	Performed the experiments	Investigation	YES
5539180	28824668	KS	2	conceived and designed the study|carried out the experiments|analyzed and interpreted the data|prepared the manuscript	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5539180	28824668	KS	2	conceived and designed the study|carried out the experiments|analyzed and interpreted the data|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5539180	28824668	SC	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5539180	28824668	TN	2	conceived and designed the study|carried out the experiments|analyzed and interpreted the data|prepared the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5539180	28824668	TN	2	conceived and designed the study|carried out the experiments|analyzed and interpreted the data|prepared the manuscript	carried out the experiments	Performed the experiments	Investigation	YES
5539180	28824668	TN	2	conceived and designed the study|carried out the experiments|analyzed and interpreted the data|prepared the manuscript	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5539180	28824668	TN	2	conceived and designed the study|carried out the experiments|analyzed and interpreted the data|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5539180	28824668	YL	2	provided the r	provided the r	-	-	NO
5312496	28228944	GD	2	contributed on data collection and analysis	contributed on data collection and analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5312496	28228944	GM	2	contributed on data collection and analysis|while he also supervised the manuscript preparation process	contributed on data collection and analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5312496	28228944	GM	2	contributed on data collection and analysis|while he also supervised the manuscript preparation process	while he also supervised the manuscript preparation process	Wrote the paper	Supervision|Writing - Original Draft	YES
5312496	28228944	GS	2	contributed on manuscript writing, study design, data collection and analysis, while he supervised the manuscript preparation process|while he also supervised the manuscript preparation process	contributed on manuscript writing, study design, data collection and analysis, while he supervised the manuscript preparation process	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Data curation|Formal analysis|Investigation|Methodology|Resources|Supervision|Writing - Original Draft	YES
5312496	28228944	GS	2	contributed on manuscript writing, study design, data collection and analysis, while he supervised the manuscript preparation process|while he also supervised the manuscript preparation process	while he also supervised the manuscript preparation process	Wrote the paper	Supervision|Writing - Original Draft	YES
5312496	28228944	SS	2	contributed on data collection and analysis|while he also supervised the manuscript preparation process	contributed on data collection and analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5312496	28228944	SS	2	contributed on data collection and analysis|while he also supervised the manuscript preparation process	while he also supervised the manuscript preparation process	Wrote the paper	Supervision|Writing - Original Draft	YES
5312496	28228944	TD	2	contributed on data collection and analysis|while he also supervised the manuscript preparation process	contributed on data collection and analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5312496	28228944	TD	2	contributed on data collection and analysis|while he also supervised the manuscript preparation process	while he also supervised the manuscript preparation process	Wrote the paper	Supervision|Writing - Original Draft	YES
4783305	26955965	AG	2	collected clinical cohort data, contributed to the study design and analysis and revised and approved the final manuscript	collected clinical cohort data, contributed to the study design and analysis and revised and approved the final manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Review & Editing	YES
4783305	26955965	BKA	2	collected clinical cohort data, contributed to the study design and analysis and revised and approved the final manuscript	collected clinical cohort data, contributed to the study design and analysis and revised and approved the final manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Review & Editing	YES
4783305	26955965	JFO	2	conceptualized and designed the study, collected clinical cohort data, interpreted the data and revised and approved the final manuscript	conceptualized and designed the study, collected clinical cohort data, interpreted the data and revised and approved the final manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Review & Editing	YES
4783305	26955965	RGD	2	collected clinical cohort data, contributed to the study design and analysis and revised and approved the final manuscript	collected clinical cohort data, contributed to the study design and analysis and revised and approved the final manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Review & Editing	YES
4783305	26955965	SAB	2	conceptualized the study, contributed to the study design and analysis and revised and approved the final manuscript	conceptualized the study, contributed to the study design and analysis and revised and approved the final manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
4783305	26955965	TAC	2	conceptualized and designed the study, conducted the initial analysis, interpreted the data and drafted the manuscript	conceptualized and designed the study, conducted the initial analysis, interpreted the data and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5282827	28143394	DY	2	designed the project and revised the manuscript	designed the project and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5282827	28143394	HZ	2	analyzed the data and wrote the manuscript|designed the project and revised the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5282827	28143394	HZ	2	analyzed the data and wrote the manuscript|designed the project and revised the manuscript	designed the project and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5282827	28143394	JW	2	performed the experiment|analyzed the data and wrote the manuscript	performed the experiment	Performed the experiments	Investigation	YES
5282827	28143394	JW	2	performed the experiment|analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5282827	28143394	XX	2	designed the project and revised the manuscript	designed the project and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
6204055	30368240	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6204055	30368240	The authors	2	declare that they no competing interests	declare that they no competing interests	-	-	NO
5312648	28228945	D. Shigemi	2	wrote the first draft and performed critical revision	wrote the first draft and performed critical revision	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5312648	28228945	S. Kamoi	2	commented on and revised the article	commented on and revised the article	Wrote the paper	Writing - Review & Editing	YES
5312648	28228945	T. Matsuhashi	2	commented on and revised the article	commented on and revised the article	Wrote the paper	Writing - Review & Editing	YES
5312648	28228945	T. Takeshita	2	commented on and revised the article	commented on and revised the article	Wrote the paper	Writing - Review & Editing	YES
5312648	28228945	T. Yamada	2	commented on and revised the article	commented on and revised the article	Wrote the paper	Writing - Review & Editing	YES
5874548	29361717	Baiba Maurina	2	provided data and information, and helped with the revisions of the manuscript	provided data and information, and helped with the revisions of the manuscript	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Review & Editing	YES
5874548	29361717	Jeffrey Atkinson	2	formatted the data, wrote the manuscript and coordinated the revisions	formatted the data, wrote the manuscript and coordinated the revisions	Analyzed the data|Wrote the paper	Data curation|Project administration|Writing - Original Draft|Writing - Review & Editing	YES
5874548	29361717	Ruta Muceniece	2	provided data and information, and helped with the revisions of the manuscript	provided data and information, and helped with the revisions of the manuscript	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Review & Editing	YES
5874548	29361717	Una Riekstina	2	provided data and information, and helped with the revisions of the manuscript	provided data and information, and helped with the revisions of the manuscript	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Review & Editing	YES
5874548	29361717	Vija Enina	2	provided data and information, and helped with the revisions of the manuscript	provided data and information, and helped with the revisions of the manuscript	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Review & Editing	YES
4405382	25898140	AM	PLoS5	Wrote the paper|Designed the study and wrote the protocol|Designed the patient survey|Conducted research at sites	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405382	25898140	AM	PLoS5	Wrote the paper|Designed the study and wrote the protocol|Designed the patient survey|Conducted research at sites	Designed the study and wrote the protocol	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4405382	25898140	AM	PLoS5	Wrote the paper|Designed the study and wrote the protocol|Designed the patient survey|Conducted research at sites	Designed the patient survey	Conceived and designed the experiments|Performed the experiments	Investigation	YES
4405382	25898140	AM	PLoS5	Wrote the paper|Designed the study and wrote the protocol|Designed the patient survey|Conducted research at sites	Conducted research at sites	Performed the experiments	Investigation	YES
4405382	25898140	DES	PLoS5	Wrote the paper|Designed the study and wrote the protocol|Designed the patient survey|Conducted research at sites	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405382	25898140	DES	PLoS5	Wrote the paper|Designed the study and wrote the protocol|Designed the patient survey|Conducted research at sites	Designed the study and wrote the protocol	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4405382	25898140	DES	PLoS5	Wrote the paper|Designed the study and wrote the protocol|Designed the patient survey|Conducted research at sites	Designed the patient survey	Conceived and designed the experiments|Performed the experiments	Investigation	YES
4405382	25898140	DES	PLoS5	Wrote the paper|Designed the study and wrote the protocol|Designed the patient survey|Conducted research at sites	Conducted research at sites	Performed the experiments	Investigation	YES
4405382	25898140	DLC	PLoS5	Wrote the paper|Designed the study and wrote the protocol|Designed the patient survey|Conducted research at sites	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405382	25898140	DLC	PLoS5	Wrote the paper|Designed the study and wrote the protocol|Designed the patient survey|Conducted research at sites	Designed the study and wrote the protocol	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4405382	25898140	DLC	PLoS5	Wrote the paper|Designed the study and wrote the protocol|Designed the patient survey|Conducted research at sites	Designed the patient survey	Conceived and designed the experiments|Performed the experiments	Investigation	YES
4405382	25898140	DLC	PLoS5	Wrote the paper|Designed the study and wrote the protocol|Designed the patient survey|Conducted research at sites	Conducted research at sites	Performed the experiments	Investigation	YES
4405382	25898140	DPC	PLoS5	Analyzed the data|Wrote the paper|Designed the study and wrote the protocol|Designed the patient survey|Project co-ordination|Staff training and quality management	Analyzed the data	Analyzed the data	Formal analysis	YES
4405382	25898140	DPC	PLoS5	Analyzed the data|Wrote the paper|Designed the study and wrote the protocol|Designed the patient survey|Project co-ordination|Staff training and quality management	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405382	25898140	DPC	PLoS5	Analyzed the data|Wrote the paper|Designed the study and wrote the protocol|Designed the patient survey|Project co-ordination|Staff training and quality management	Designed the study and wrote the protocol	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4405382	25898140	DPC	PLoS5	Analyzed the data|Wrote the paper|Designed the study and wrote the protocol|Designed the patient survey|Project co-ordination|Staff training and quality management	Designed the patient survey	Conceived and designed the experiments|Performed the experiments	Investigation	YES
4405382	25898140	DPC	PLoS5	Analyzed the data|Wrote the paper|Designed the study and wrote the protocol|Designed the patient survey|Project co-ordination|Staff training and quality management	Project co-ordination	-	Project administration	YES
4405382	25898140	DPC	PLoS5	Analyzed the data|Wrote the paper|Designed the study and wrote the protocol|Designed the patient survey|Project co-ordination|Staff training and quality management	Staff training and quality management	-	-	NO
4405382	25898140	MH	PLoS5	Analyzed the data|Wrote the paper|Designed the study and wrote the protocol|Designed the patient survey	Analyzed the data	Analyzed the data	Formal analysis	YES
4405382	25898140	MH	PLoS5	Analyzed the data|Wrote the paper|Designed the study and wrote the protocol|Designed the patient survey	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405382	25898140	MH	PLoS5	Analyzed the data|Wrote the paper|Designed the study and wrote the protocol|Designed the patient survey	Designed the study and wrote the protocol	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4405382	25898140	MH	PLoS5	Analyzed the data|Wrote the paper|Designed the study and wrote the protocol|Designed the patient survey	Designed the patient survey	Conceived and designed the experiments|Performed the experiments	Investigation	YES
4405382	25898140	PC	PLoS5	Wrote the paper|Designed the study and wrote the protocol|Staff training and quality management	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405382	25898140	PC	PLoS5	Wrote the paper|Designed the study and wrote the protocol|Staff training and quality management	Designed the study and wrote the protocol	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4405382	25898140	PC	PLoS5	Wrote the paper|Designed the study and wrote the protocol|Staff training and quality management	Staff training and quality management	-	-	NO
4405382	25898140	PK	PLoS5	Wrote the paper|Designed the study and wrote the protocol|Designed the patient survey|Project co-ordination	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405382	25898140	PK	PLoS5	Wrote the paper|Designed the study and wrote the protocol|Designed the patient survey|Project co-ordination	Designed the study and wrote the protocol	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4405382	25898140	PK	PLoS5	Wrote the paper|Designed the study and wrote the protocol|Designed the patient survey|Project co-ordination	Designed the patient survey	Conceived and designed the experiments|Performed the experiments	Investigation	YES
4405382	25898140	PK	PLoS5	Wrote the paper|Designed the study and wrote the protocol|Designed the patient survey|Project co-ordination	Project co-ordination	-	Project administration	YES
4405382	25898140	RG	PLoS5	Analyzed the data|Wrote the paper|Designed the study and wrote the protocol|Designed the patient survey|Project co-ordination	Analyzed the data	Analyzed the data	Formal analysis	YES
4405382	25898140	RG	PLoS5	Analyzed the data|Wrote the paper|Designed the study and wrote the protocol|Designed the patient survey|Project co-ordination	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405382	25898140	RG	PLoS5	Analyzed the data|Wrote the paper|Designed the study and wrote the protocol|Designed the patient survey|Project co-ordination	Designed the study and wrote the protocol	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4405382	25898140	RG	PLoS5	Analyzed the data|Wrote the paper|Designed the study and wrote the protocol|Designed the patient survey|Project co-ordination	Designed the patient survey	Conceived and designed the experiments|Performed the experiments	Investigation	YES
4405382	25898140	RG	PLoS5	Analyzed the data|Wrote the paper|Designed the study and wrote the protocol|Designed the patient survey|Project co-ordination	Project co-ordination	-	Project administration	YES
4405382	25898140	SCD	PLoS5	Wrote the paper|Designed the study and wrote the protocol|Designed the patient survey|Conducted research at sites	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405382	25898140	SCD	PLoS5	Wrote the paper|Designed the study and wrote the protocol|Designed the patient survey|Conducted research at sites	Designed the study and wrote the protocol	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4405382	25898140	SCD	PLoS5	Wrote the paper|Designed the study and wrote the protocol|Designed the patient survey|Conducted research at sites	Designed the patient survey	Conceived and designed the experiments|Performed the experiments	Investigation	YES
4405382	25898140	SCD	PLoS5	Wrote the paper|Designed the study and wrote the protocol|Designed the patient survey|Conducted research at sites	Conducted research at sites	Performed the experiments	Investigation	YES
5539183	28824687	LJ	PLoS52	designed the experiments|performed the experiments|drafted the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5539183	28824687	LJ	PLoS52	designed the experiments|performed the experiments|drafted the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5539183	28824687	LJ	PLoS52	designed the experiments|performed the experiments|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5539183	28824687	MN	PLoS52	designed the experiments|drafted the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5539183	28824687	MN	PLoS52	designed the experiments|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5539183	28824687	RS	PLoS52	performed the experiments|analyzed the data|drafted the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5539183	28824687	RS	PLoS52	performed the experiments|analyzed the data|drafted the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5539183	28824687	RS	PLoS52	performed the experiments|analyzed the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5282891	28143393	All authors	2	read and revised the manuscript	read and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5282891	28143393	CKC	2	conceived this study|designed the experiments|collected all the animal samples|carried out the bioinformatics analysis|performed the experimental validations|generated all images|wrote the manuscript	conceived this study	Conceived and designed the experiments	Conceptualization	YES
5282891	28143393	CKC	2	conceived this study|designed the experiments|collected all the animal samples|carried out the bioinformatics analysis|performed the experimental validations|generated all images|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5282891	28143393	CKC	2	conceived this study|designed the experiments|collected all the animal samples|carried out the bioinformatics analysis|performed the experimental validations|generated all images|wrote the manuscript	collected all the animal samples	Performed the experiments	Investigation	YES
5282891	28143393	CKC	2	conceived this study|designed the experiments|collected all the animal samples|carried out the bioinformatics analysis|performed the experimental validations|generated all images|wrote the manuscript	carried out the bioinformatics analysis	Performed the experiments	Formal analysis|Investigation	YES
5282891	28143393	CKC	2	conceived this study|designed the experiments|collected all the animal samples|carried out the bioinformatics analysis|performed the experimental validations|generated all images|wrote the manuscript	performed the experimental validations	Performed the experiments	Investigation|Validation	YES
5282891	28143393	CKC	2	conceived this study|designed the experiments|collected all the animal samples|carried out the bioinformatics analysis|performed the experimental validations|generated all images|wrote the manuscript	generated all images	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
5282891	28143393	CKC	2	conceived this study|designed the experiments|collected all the animal samples|carried out the bioinformatics analysis|performed the experimental validations|generated all images|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5282891	28143393	CPY	2	designed the experiments|carried out the bioinformatics analysis|generated all images|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5282891	28143393	CPY	2	designed the experiments|carried out the bioinformatics analysis|generated all images|wrote the manuscript	carried out the bioinformatics analysis	Performed the experiments	Formal analysis|Investigation	YES
5282891	28143393	CPY	2	designed the experiments|carried out the bioinformatics analysis|generated all images|wrote the manuscript	generated all images	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
5282891	28143393	CPY	2	designed the experiments|carried out the bioinformatics analysis|generated all images|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5282891	28143393	CSN	2	conceived this study|designed the experiments|wrote the manuscript	conceived this study	Conceived and designed the experiments	Conceptualization	YES
5282891	28143393	CSN	2	conceived this study|designed the experiments|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5282891	28143393	CSN	2	conceived this study|designed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5282891	28143393	CTT	2	designed the experiments|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5282891	28143393	CTT	2	designed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5282891	28143393	DRC	2	conducted the transcriptome sequencing	conducted the transcriptome sequencing	Performed the experiments	Investigation	YES
5282891	28143393	MYJL	2	conducted the transcriptome sequencing	conducted the transcriptome sequencing	Performed the experiments	Investigation	YES
5282891	28143393	SCL	2	developed the lncrna prediction pipeline	developed the lncrna prediction pipeline	Analyzed the data	Formal analysis	YES
5282891	28143393	SMW	2	performed the experimental validations|generated all images	performed the experimental validations	Performed the experiments	Investigation|Validation	YES
5282891	28143393	SMW	2	performed the experimental validations|generated all images	generated all images	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
5282891	28143393	WHL	2	conceived this study|designed the experiments|wrote the manuscript	conceived this study	Conceived and designed the experiments	Conceptualization	YES
5282891	28143393	WHL	2	conceived this study|designed the experiments|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5282891	28143393	WHL	2	conceived this study|designed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5282891	28143393	YHC	2	conducted the transcriptome sequencing	conducted the transcriptome sequencing	Performed the experiments	Investigation	YES
6320330	30610400	All authors	2	have contributed to all aspects of the pilot study, analyses and writing of the manuscript|read and approved the final manuscript	have contributed to all aspects of the pilot study, analyses and writing of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6320330	30610400	All authors	2	have contributed to all aspects of the pilot study, analyses and writing of the manuscript|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4788772	26968214	HT	2	provided technical input into study design, data collection, interpretation of results and reviewed the manuscript	provided technical input into study design, data collection, interpretation of results and reviewed the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Review & Editing	YES
4788772	26968214	MW	2	provided technical input into study design, data collection, interpretation of results and reviewed the manuscript	provided technical input into study design, data collection, interpretation of results and reviewed the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Review & Editing	YES
4788772	26968214	NP	2	provided technical support, supervised data collection, interpreted the findings and reviewed the manuscript	provided technical support, supervised data collection, interpreted the findings and reviewed the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Supervision|Writing - Review & Editing	YES
4788772	26968214	NV	2	provided technical support, supervised data collection, interpreted the findings and reviewed the manuscript|provided technical input into study design, data collection, interpretation of results and reviewed the manuscript	provided technical support, supervised data collection, interpreted the findings and reviewed the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Supervision|Writing - Review & Editing	YES
4788772	26968214	NV	2	provided technical support, supervised data collection, interpreted the findings and reviewed the manuscript|provided technical input into study design, data collection, interpretation of results and reviewed the manuscript	provided technical input into study design, data collection, interpretation of results and reviewed the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Review & Editing	YES
4788772	26968214	PL	2	provided technical input into study design, data collection, interpretation of results and reviewed the manuscript	provided technical input into study design, data collection, interpretation of results and reviewed the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Review & Editing	YES
4788772	26968214	RG	2	conceptualized the design of the study, developed data collection tools, oversaw study implementation, data analysis, drafted and finalized the manuscript	conceptualized the design of the study, developed data collection tools, oversaw study implementation, data analysis, drafted and finalized the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
4788772	26968214	RL	2	conceptualized the design of the study, developed data collection tools, oversaw study implementation, data analysis, drafted and finalized the manuscript	conceptualized the design of the study, developed data collection tools, oversaw study implementation, data analysis, drafted and finalized the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
4788772	26968214	SB	2	provided technical input into study design, data collection, interpretation of results and reviewed the manuscript	provided technical input into study design, data collection, interpretation of results and reviewed the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Review & Editing	YES
4788772	26968214	TN	2	conceptualized the design of the study, developed data collection tools, oversaw study implementation, data analysis, drafted and finalized the manuscript	conceptualized the design of the study, developed data collection tools, oversaw study implementation, data analysis, drafted and finalized the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
6206661	30373620	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5328746	28275425	Carlo Setacci	2	overall responsibility	overall responsibility	-	-	NO
5328746	28275425	Francesco Speziale	2	data interpretation, overall responsability	data interpretation, overall responsability	Analyzed the data	Formal analysis	YES
5328746	28275425	Giovanna Ricci	2	data collection and analysis	data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5328746	28275425	Paola Frati	2	data collection and analysis	data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5328746	28275425	Study Concept	2	overall responsibility	overall responsibility	-	-	NO
5328746	28275425	Vittorio Fineschi	2	data interpretation, overall responsability	data interpretation, overall responsability	Analyzed the data	Formal analysis	YES
5874549	29361723	Donatella Zodda	2	were involved in the study conception and design	were involved in the study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5874549	29361723	Rosario Giammona	2	were involved in the study conception and design	were involved in the study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5874549	29361723	Silvia Schifilliti	2	were involved in the study conception and design	were involved in the study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405383	25898210	ES	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405383	25898210	ES	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405383	25898210	ES	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405383	25898210	MOM	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5539188	28824665	JW	7	drafting the work or revising it critically for important intellectual content	drafting the work or revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5539188	28824665	JX	7	substantial contributions to the design of the work. Substantial contributions to the acquisition, analysis, interpretation of data for the work	substantial contributions to the design of the work. Substantial contributions to the acquisition, analysis, interpretation of data for the work	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5539188	28824665	QC	7	agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved. Final approval of the version to be published	agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved. Final approval of the version to be published	-	-	NO
5539188	28824665	WL	7	agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved. Final approval of the version to be published	agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved. Final approval of the version to be published	-	-	NO
5539188	28824665	YT	7	drafting the work or revising it critically for important intellectual content	drafting the work or revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6078114	30094282	BP	2	was the pi of the study and was involved in the study conceptualization, design, data collection, analysis, and manuscript drafting and revising	was the pi of the study and was involved in the study conceptualization, design, data collection, analysis, and manuscript drafting and revising	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
6078114	30094282	CC	2	was involved in the study conceptualization, design, and manuscript drafting and revising, and provided guidance on data collection and analysis	was involved in the study conceptualization, design, and manuscript drafting and revising, and provided guidance on data collection and analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Resources|Supervision|Writing - Original Draft	YES
6078114	30094282	EP	2	was involved in the study conceptualization, design, and manuscript drafting and revising, and provided guidance on data collection and analysis	was involved in the study conceptualization, design, and manuscript drafting and revising, and provided guidance on data collection and analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Resources|Supervision|Writing - Original Draft	YES
6078114	30094282	VF	2	was involved in the study conceptualization, design, and manuscript drafting and revising, and provided guidance on data collection and analysis	was involved in the study conceptualization, design, and manuscript drafting and revising, and provided guidance on data collection and analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Resources|Supervision|Writing - Original Draft	YES
6330377	30637531	AD	2	contributed to the design and follow up of the study	contributed to the design and follow up of the study	Conceived and designed the experiments	Methodology	YES
6330377	30637531	ALK	2	were responsible for the recruitment and interviews of the participants, the acquisition of the data and the management of the clinical database	were responsible for the recruitment and interviews of the participants, the acquisition of the data and the management of the clinical database	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Investigation|Software	YES
6330377	30637531	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6330377	30637531	CP	2	conceived, designed and supervised the entire study and wrote the manuscript	conceived, designed and supervised the entire study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Supervision|Writing - Original Draft	YES
6330377	30637531	JMA	2	contributed to the design of the study, funding obtainment and patient recruitment	contributed to the design of the study, funding obtainment and patient recruitment	Conceived and designed the experiments|Performed the experiments	Funding acquisition|Investigation|Methodology	YES
6330377	30637531	KA	2	analyzed and interpreted the data of both patients and controls and wrote the manuscript	analyzed and interpreted the data of both patients and controls and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6330377	30637531	PC	2	were responsible for the recruitment and interviews of the participants, the acquisition of the data and the management of the clinical database	were responsible for the recruitment and interviews of the participants, the acquisition of the data and the management of the clinical database	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Investigation|Software	YES
6330377	30637531	PV	2	contributed to the design of the study, the fmri data analysis and interpretation and in writing the manuscript	contributed to the design of the study, the fmri data analysis and interpretation and in writing the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Original Draft	YES
6330377	30637531	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5329067	28275426	Alanoud Alomair	1	Study design	Study design	Conceived and designed the experiments	Methodology	YES
5329067	28275426	Amani Albjadi	1	Study design	Study design	Conceived and designed the experiments	Methodology	YES
5329067	28275426	Sara Alsaddiqi	1	Writing	Writing	Wrote the paper	-	YES
5329067	28275426	Waad Abdullah	1	Study design	Study design	Conceived and designed the experiments	Methodology	YES
5329067	28275426	Yara Alsalloum	1	Study design|Writing	Study design	Conceived and designed the experiments	Methodology	YES
5329067	28275426	Yara Alsalloum	1	Study design|Writing	Writing	Wrote the paper	-	YES
5329067	28275426	Yossef Alnasser	1	Study design|Writing	Study design	Conceived and designed the experiments	Methodology	YES
5329067	28275426	Yossef Alnasser	1	Study design|Writing	Writing	Wrote the paper	-	YES
4789547	26976377	ADH	2	contributed to the concept and design of the study|reviewed and suggested revisions	contributed to the concept and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4789547	26976377	ADH	2	contributed to the concept and design of the study|reviewed and suggested revisions	reviewed and suggested revisions	Wrote the paper	Writing - Review & Editing	YES
4789547	26976377	AKC	2	contributed to the concept and design of the study|drafted the first manuscript	contributed to the concept and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4789547	26976377	AKC	2	contributed to the concept and design of the study|drafted the first manuscript	drafted the first manuscript	Wrote the paper	Writing - Original Draft	YES
4789547	26976377	All authors	2	reviewed and approved the final manuscript	reviewed and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4789547	26976377	EK	2	contributed to the concept and design of the study|contributed to acquisition of data	contributed to the concept and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4789547	26976377	EK	2	contributed to the concept and design of the study|contributed to acquisition of data	contributed to acquisition of data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4789547	26976377	IM	2	contributed to acquisition of data|reviewed and suggested revisions	contributed to acquisition of data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4789547	26976377	IM	2	contributed to acquisition of data|reviewed and suggested revisions	reviewed and suggested revisions	Wrote the paper	Writing - Review & Editing	YES
4789547	26976377	JJvO	2	contributed to the concept and design of the study|contributed to data analysis and/or interpretation of the data|drafted the first manuscript	contributed to the concept and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4789547	26976377	JJvO	2	contributed to the concept and design of the study|contributed to data analysis and/or interpretation of the data|drafted the first manuscript	contributed to data analysis and/or interpretation of the data	Analyzed the data	Formal analysis	YES
4789547	26976377	JJvO	2	contributed to the concept and design of the study|contributed to data analysis and/or interpretation of the data|drafted the first manuscript	drafted the first manuscript	Wrote the paper	Writing - Original Draft	YES
4789547	26976377	MvL	2	contributed to the concept and design of the study|contributed to acquisition of data|contributed to data analysis and/or interpretation of the data|drafted the first manuscript	contributed to the concept and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4789547	26976377	MvL	2	contributed to the concept and design of the study|contributed to acquisition of data|contributed to data analysis and/or interpretation of the data|drafted the first manuscript	contributed to acquisition of data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4789547	26976377	MvL	2	contributed to the concept and design of the study|contributed to acquisition of data|contributed to data analysis and/or interpretation of the data|drafted the first manuscript	contributed to data analysis and/or interpretation of the data	Analyzed the data	Formal analysis	YES
4789547	26976377	MvL	2	contributed to the concept and design of the study|contributed to acquisition of data|contributed to data analysis and/or interpretation of the data|drafted the first manuscript	drafted the first manuscript	Wrote the paper	Writing - Original Draft	YES
4789547	26976377	RB	2	contributed to the concept and design of the study|reviewed and suggested revisions	contributed to the concept and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4789547	26976377	RB	2	contributed to the concept and design of the study|reviewed and suggested revisions	reviewed and suggested revisions	Wrote the paper	Writing - Review & Editing	YES
4789547	26976377	RM	2	contributed to acquisition of data|reviewed and suggested revisions	contributed to acquisition of data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4789547	26976377	RM	2	contributed to acquisition of data|reviewed and suggested revisions	reviewed and suggested revisions	Wrote the paper	Writing - Review & Editing	YES
4789547	26976377	WM	2	contributed to acquisition of data|reviewed and suggested revisions	contributed to acquisition of data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4789547	26976377	WM	2	contributed to acquisition of data|reviewed and suggested revisions	reviewed and suggested revisions	Wrote the paper	Writing - Review & Editing	YES
6223033	30409215	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6223033	30409215	CS	2	performed molecular and sequencing experiments	performed molecular and sequencing experiments	Performed the experiments	Investigation	YES
6223033	30409215	DC	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
6223033	30409215	DJA	2	contributed to the overall analysis of the data	contributed to the overall analysis of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6223033	30409215	DW	2	performed molecular and sequencing experiments	performed molecular and sequencing experiments	Performed the experiments	Investigation	YES
6223033	30409215	FSH	2	provided most needed logistics for the implementation of the deepgentm assay in the united kingdom	provided most needed logistics for the implementation of the deepgentm assay in the united kingdom	Performed the experiments	Investigation|Project administration	YES
6223033	30409215	GM	2	performed molecular and sequencing experiments	performed molecular and sequencing experiments	Performed the experiments	Investigation	YES
6223033	30409215	JS	2	performed molecular and sequencing experiments	performed molecular and sequencing experiments	Performed the experiments	Investigation	YES
6223033	30409215	KB	2	provided most needed logistics for the implementation of the deepgentm assay in the united kingdom	provided most needed logistics for the implementation of the deepgentm assay in the united kingdom	Performed the experiments	Investigation|Project administration	YES
6223033	30409215	KT	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
6223033	30409215	MA	2	performed molecular and sequencing experiments	performed molecular and sequencing experiments	Performed the experiments	Investigation	YES
6223033	30409215	MEQ-M	2	designed the study|contributed to the overall analysis of the data|collected and assembled the data, wrote and drafted the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
6223033	30409215	MEQ-M	2	designed the study|contributed to the overall analysis of the data|collected and assembled the data, wrote and drafted the manuscript	contributed to the overall analysis of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6223033	30409215	MEQ-M	2	designed the study|contributed to the overall analysis of the data|collected and assembled the data, wrote and drafted the manuscript	collected and assembled the data, wrote and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6223033	30409215	MP	2	performed molecular and sequencing experiments	performed molecular and sequencing experiments	Performed the experiments	Investigation	YES
6223033	30409215	NS	2	performed molecular and sequencing experiments	performed molecular and sequencing experiments	Performed the experiments	Investigation	YES
5874550	29361750	C.H.	PLoS52	collected the data|analyzed the data|wrote the paper	collected the data	Performed the experiments	Investigation	YES
5874550	29361750	C.H.	PLoS52	collected the data|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5874550	29361750	C.H.	PLoS52	collected the data|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5874550	29361750	D.R.A.	PLoS52	analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5874550	29361750	D.R.A.	PLoS52	analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5874550	29361750	J.L.	PLoS52	conceived and designed the study|wrote the paper	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5874550	29361750	J.L.	PLoS52	conceived and designed the study|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5874550	29361750	M.S.	PLoS52	conceived and designed the study|wrote the paper	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5874550	29361750	M.S.	PLoS52	conceived and designed the study|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405390	25897786	CSB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405390	25897786	CSB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405390	25897786	CSB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405390	25897786	CSB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405390	25897786	EJG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405390	25897786	EJG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4405390	25897786	EJG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405390	25897786	MM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405390	25897786	MM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405390	25897786	MM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405390	25897786	MM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405390	25897786	RS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4405390	25897786	RS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405390	25897786	RVS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405390	25897786	SB	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4405390	25897786	SB	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405390	25897786	SVC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405390	25897786	VB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405390	25897786	ZM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4405390	25897786	ZM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5282909	28143399	CXL	2	conceived the idea, design the experiment, analyzed the data and drafted the manuscript	conceived the idea, design the experiment, analyzed the data and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
5282909	28143399	TZZ	2	conceptualized the research program and revised the manuscript	conceptualized the research program and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5331157	28275427	Aashish Rajesh-Data	2	analysis and writing the paper	analysis and writing the paper	Wrote the paper	Writing - Original Draft	YES
5331157	28275427	Both authors	2	consent to share the post of first authors as equal contributions were made	consent to share the post of first authors as equal contributions were made	-	-	NO
5331157	28275427	Mohammed Farooq-Acquisition	2	of data, performance of surgery and viewing the final draft	of data, performance of surgery and viewing the final draft	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6355891	30706154	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6355891	30706154	EMC	2	contributed to the final version of the manuscript	contributed to the final version of the manuscript	-	-	NO
6355891	30706154	JB	2	contributed to the final version of the manuscript	contributed to the final version of the manuscript	-	-	NO
6355891	30706154	LVK	2	performed the statistical analyses and wrote the first draft of the manuscript|contributed to the final version of the manuscript	performed the statistical analyses and wrote the first draft of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6355891	30706154	LVK	2	performed the statistical analyses and wrote the first draft of the manuscript|contributed to the final version of the manuscript	contributed to the final version of the manuscript	-	-	NO
6355891	30706154	MF	2	contributed to the final version of the manuscript	contributed to the final version of the manuscript	-	-	NO
6355891	30706154	MFJ	2	performed the statistical analyses and wrote the first draft of the manuscript|contributed to the final version of the manuscript	performed the statistical analyses and wrote the first draft of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6355891	30706154	MFJ	2	performed the statistical analyses and wrote the first draft of the manuscript|contributed to the final version of the manuscript	contributed to the final version of the manuscript	-	-	NO
6355891	30706154	MV	2	contributed to the final version of the manuscript	contributed to the final version of the manuscript	-	-	NO
5539191	28824658	DE	CRediT	Production of the data	Production of the data	Performed the experiments	Investigation	YES
5539191	28824658	MS	CRediT	Conception of the study|Data analysis|Writing of the manuscript	Conception of the study	Conceived and designed the experiments	Conceptualization	YES
5539191	28824658	MS	CRediT	Conception of the study|Data analysis|Writing of the manuscript	Data analysis	Analyzed the data	Formal analysis	YES
5539191	28824658	MS	CRediT	Conception of the study|Data analysis|Writing of the manuscript	Writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5539191	28824658	RV	CRediT	Writing of the manuscript	Writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5539191	28824658	SI	CRediT	Conception of the study|Collection of material|Production of the data|Data analysis|Writing of the manuscript	Conception of the study	Conceived and designed the experiments	Conceptualization	YES
5539191	28824658	SI	CRediT	Conception of the study|Collection of material|Production of the data|Data analysis|Writing of the manuscript	Collection of material	Performed the experiments	Investigation	YES
5539191	28824658	SI	CRediT	Conception of the study|Collection of material|Production of the data|Data analysis|Writing of the manuscript	Production of the data	Performed the experiments	Investigation	YES
5539191	28824658	SI	CRediT	Conception of the study|Collection of material|Production of the data|Data analysis|Writing of the manuscript	Data analysis	Analyzed the data	Formal analysis	YES
5539191	28824658	SI	CRediT	Conception of the study|Collection of material|Production of the data|Data analysis|Writing of the manuscript	Writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5539191	28824658	TB	CRediT	Conception of the study|Production of the data|Software|Data analysis|Writing of the manuscript	Conception of the study	Conceived and designed the experiments	Conceptualization	YES
5539191	28824658	TB	CRediT	Conception of the study|Production of the data|Software|Data analysis|Writing of the manuscript	Production of the data	Performed the experiments	Investigation	YES
5539191	28824658	TB	CRediT	Conception of the study|Production of the data|Software|Data analysis|Writing of the manuscript	Software	Contributed reagents/materials/analysis tools	Software	YES
5539191	28824658	TB	CRediT	Conception of the study|Production of the data|Software|Data analysis|Writing of the manuscript	Data analysis	Analyzed the data	Formal analysis	YES
5539191	28824658	TB	CRediT	Conception of the study|Production of the data|Software|Data analysis|Writing of the manuscript	Writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
4793284	26979535	All authors	2	have critically read the manuscript	have critically read the manuscript	-	-	NO
4793284	26979535	CLT	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4793284	26979535	HW	2	collected the data	collected the data	Performed the experiments	Investigation	YES
4793284	26979535	JX	2	collected the data|drafted the manuscript	collected the data	Performed the experiments	Investigation	YES
4793284	26979535	JX	2	collected the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4793284	26979535	TL	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4793284	26979535	XS	2	collected the data	collected the data	Performed the experiments	Investigation	YES
4793284	26979535	YH	2	collected the data	collected the data	Performed the experiments	Investigation	YES
4793284	26979535	YL	2	collected the data|collected the data	collected the data	Performed the experiments	Investigation	YES
4793284	26979535	YL	2	collected the data|collected the data	collected the data	Performed the experiments	Investigation	YES
4793284	26979535	ZQ	2	collected the data	collected the data	Performed the experiments	Investigation	YES
4405423	25898340	CO	PLoS5	Conceived and designed the experiments|Wrote the paper|Acquisition of data|Contributed intellectually to the interpretation and discussion of results	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405423	25898340	CO	PLoS5	Conceived and designed the experiments|Wrote the paper|Acquisition of data|Contributed intellectually to the interpretation and discussion of results	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405423	25898340	CO	PLoS5	Conceived and designed the experiments|Wrote the paper|Acquisition of data|Contributed intellectually to the interpretation and discussion of results	Acquisition of data	Performed the experiments	Investigation	YES
4405423	25898340	CO	PLoS5	Conceived and designed the experiments|Wrote the paper|Acquisition of data|Contributed intellectually to the interpretation and discussion of results	Contributed intellectually to the interpretation and discussion of results	Analyzed the data	Formal analysis	YES
4405423	25898340	CSB	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper|Acquisition of data|Contributed intellectually to the interpretation and discussion of results	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405423	25898340	CSB	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper|Acquisition of data|Contributed intellectually to the interpretation and discussion of results	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405423	25898340	CSB	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper|Acquisition of data|Contributed intellectually to the interpretation and discussion of results	Acquisition of data	Performed the experiments	Investigation	YES
4405423	25898340	CSB	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper|Acquisition of data|Contributed intellectually to the interpretation and discussion of results	Contributed intellectually to the interpretation and discussion of results	Analyzed the data	Formal analysis	YES
4405423	25898340	EP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Acquisition of data|Contributed intellectually to the interpretation and discussion of results	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405423	25898340	EP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Acquisition of data|Contributed intellectually to the interpretation and discussion of results	Performed the experiments	Performed the experiments	Investigation	YES
4405423	25898340	EP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Acquisition of data|Contributed intellectually to the interpretation and discussion of results	Analyzed the data	Analyzed the data	Formal analysis	YES
4405423	25898340	EP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Acquisition of data|Contributed intellectually to the interpretation and discussion of results	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405423	25898340	EP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Acquisition of data|Contributed intellectually to the interpretation and discussion of results	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405423	25898340	EP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Acquisition of data|Contributed intellectually to the interpretation and discussion of results	Acquisition of data	Performed the experiments	Investigation	YES
4405423	25898340	EP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Acquisition of data|Contributed intellectually to the interpretation and discussion of results	Contributed intellectually to the interpretation and discussion of results	Analyzed the data	Formal analysis	YES
4405423	25898340	MJPA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Acquisition of data|Contributed intellectually to the interpretation and discussion of results	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405423	25898340	MJPA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Acquisition of data|Contributed intellectually to the interpretation and discussion of results	Performed the experiments	Performed the experiments	Investigation	YES
4405423	25898340	MJPA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Acquisition of data|Contributed intellectually to the interpretation and discussion of results	Analyzed the data	Analyzed the data	Formal analysis	YES
4405423	25898340	MJPA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Acquisition of data|Contributed intellectually to the interpretation and discussion of results	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405423	25898340	MJPA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Acquisition of data|Contributed intellectually to the interpretation and discussion of results	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405423	25898340	MJPA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Acquisition of data|Contributed intellectually to the interpretation and discussion of results	Acquisition of data	Performed the experiments	Investigation	YES
4405423	25898340	MJPA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Acquisition of data|Contributed intellectually to the interpretation and discussion of results	Contributed intellectually to the interpretation and discussion of results	Analyzed the data	Formal analysis	YES
4405423	25898340	RH	PLoS5	Performed the experiments|Wrote the paper|Acquisition of data|Contributed intellectually to the interpretation and discussion of results	Performed the experiments	Performed the experiments	Investigation	YES
4405423	25898340	RH	PLoS5	Performed the experiments|Wrote the paper|Acquisition of data|Contributed intellectually to the interpretation and discussion of results	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405423	25898340	RH	PLoS5	Performed the experiments|Wrote the paper|Acquisition of data|Contributed intellectually to the interpretation and discussion of results	Acquisition of data	Performed the experiments	Investigation	YES
4405423	25898340	RH	PLoS5	Performed the experiments|Wrote the paper|Acquisition of data|Contributed intellectually to the interpretation and discussion of results	Contributed intellectually to the interpretation and discussion of results	Analyzed the data	Formal analysis	YES
4405423	25898340	RM	PLoS5	Acquisition of data	Acquisition of data	Performed the experiments	Investigation	YES
4486282	26161395	Michela Croce	2	equally contributed to the work	equally contributed to the work	-	-	NO
4486282	26161395	Sara Stigliani	2	equally contributed to the work	equally contributed to the work	-	-	NO
5338719	28289542	All authors	1	Analysis and interpretation of data	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
5338719	28289542	all authors	1	Critical revision of the manuscript for important intellectual content	Critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
6240180	30445966	MB	2	wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
6240180	30445966	The author	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5286691	28143407	DGR	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5286691	28143407	ELJ	PLoS52	performed the experiments|analyzed the data|conceived the study|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5286691	28143407	ELJ	PLoS52	performed the experiments|analyzed the data|conceived the study|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5286691	28143407	ELJ	PLoS52	performed the experiments|analyzed the data|conceived the study|wrote the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5286691	28143407	ELJ	PLoS52	performed the experiments|analyzed the data|conceived the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5286691	28143407	HAC	PLoS52	conceived the study|wrote the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5286691	28143407	HAC	PLoS52	conceived the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5874552	29382062	A.L.	2	was the chief investigator and project lead	was the chief investigator and project lead	-	-	NO
5874552	29382062	All of the authors	2	helped draft the manuscript	helped draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5874552	29382062	B.M.	2	analyzed the data and facilitated write up	analyzed the data and facilitated write up	Analyzed the data|Wrote the paper	Formal analysis	YES
5874552	29382062	N.A.	2	helped conceive and design the study and was integral to participant recruitment and data collection	helped conceive and design the study and was integral to participant recruitment and data collection	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
5874552	29382062	S.T.	2	analyzed the data and facilitated write up	analyzed the data and facilitated write up	Analyzed the data|Wrote the paper	Formal analysis	YES
6368934	30739250	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6368934	30739250	FB	2	included all participants and provided the data necessary for our analysis	included all participants and provided the data necessary for our analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6368934	30739250	GS	2	undertook the statistical analyses and managed the literature searches and analyses, and wrote the draft of the manuscript	undertook the statistical analyses and managed the literature searches and analyses, and wrote the draft of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6368934	30739250	HAD	2	designed the study and wrote the protocol|assessed percentages of lymphoid subsets|assisted the preparation and proofreading of the manuscript	designed the study and wrote the protocol	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
6368934	30739250	HAD	2	designed the study and wrote the protocol|assessed percentages of lymphoid subsets|assisted the preparation and proofreading of the manuscript	assessed percentages of lymphoid subsets	-	-	NO
6368934	30739250	HAD	2	designed the study and wrote the protocol|assessed percentages of lymphoid subsets|assisted the preparation and proofreading of the manuscript	assisted the preparation and proofreading of the manuscript	Wrote the paper	Writing - Original Draft	YES
6368934	30739250	MHJH	2	designed the study and wrote the protocol|included all participants and provided the data necessary for our analysis|assisted the preparation and proofreading of the manuscript	designed the study and wrote the protocol	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
6368934	30739250	MHJH	2	designed the study and wrote the protocol|included all participants and provided the data necessary for our analysis|assisted the preparation and proofreading of the manuscript	included all participants and provided the data necessary for our analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6368934	30739250	MHJH	2	designed the study and wrote the protocol|included all participants and provided the data necessary for our analysis|assisted the preparation and proofreading of the manuscript	assisted the preparation and proofreading of the manuscript	Wrote the paper	Writing - Original Draft	YES
6368934	30739250	RB	2	undertook the statistical analyses and managed the literature searches and analyses, and wrote the draft of the manuscript|assisted the preparation and proofreading of the manuscript	undertook the statistical analyses and managed the literature searches and analyses, and wrote the draft of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6368934	30739250	RB	2	undertook the statistical analyses and managed the literature searches and analyses, and wrote the draft of the manuscript|assisted the preparation and proofreading of the manuscript	assisted the preparation and proofreading of the manuscript	Wrote the paper	Writing - Original Draft	YES
6368934	30739250	SK	2	included all participants and provided the data necessary for our analysis	included all participants and provided the data necessary for our analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6368934	30739250	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5539238	28824662	EP	2	contributed with the analyzed the data and wrote the article with	contributed with the analyzed the data and wrote the article with	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
5539238	28824662	GB	2	contributed with the analyzed the data and wrote the article with	contributed with the analyzed the data and wrote the article with	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
5539238	28824662	HAb	2	provided assistance with data analysis	provided assistance with data analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5539238	28824662	HAs	2	contributed with the analyzed the data and wrote the article with	contributed with the analyzed the data and wrote the article with	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
5539238	28824662	KS	2	planned and performed most of the experiments, analyzed the data and wrote the article with	planned and performed most of the experiments, analyzed the data and wrote the article with	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
5539238	28824662	KV	2	contributed with the analyzed the data and wrote the article with|supervised the research	contributed with the analyzed the data and wrote the article with	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
5539238	28824662	KV	2	contributed with the analyzed the data and wrote the article with|supervised the research	supervised the research	-	Supervision	YES
5539238	28824662	MM	2	performed next generation sequencing	performed next generation sequencing	Performed the experiments	Investigation	YES
5539238	28824662	SS	2	provided assistance with data analysis	provided assistance with data analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6078121	30094283	All authors	2	contributed to the conception, design, analysis, and interpretation of this feasibility study results|commented on manuscript drafts and gave their approval for the final version to be published	contributed to the conception, design, analysis, and interpretation of this feasibility study results	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
6078121	30094283	All authors	2	contributed to the conception, design, analysis, and interpretation of this feasibility study results|commented on manuscript drafts and gave their approval for the final version to be published	commented on manuscript drafts and gave their approval for the final version to be published	Wrote the paper	Writing - Original Draft	YES
6078121	30094283	JB	2	contributed to the conception and design, drafting of the manuscript or revising it for critical important intellectual content	contributed to the conception and design, drafting of the manuscript or revising it for critical important intellectual content	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
6078121	30094283	JMM	2	contributed to the conception and design, drafting of the manuscript or revising it for critical important intellectual content	contributed to the conception and design, drafting of the manuscript or revising it for critical important intellectual content	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
6078121	30094283	JY	2	contributed to the conception and design, drafting of the manuscript or revising it for critical important intellectual content	contributed to the conception and design, drafting of the manuscript or revising it for critical important intellectual content	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
6078121	30094283	LL	2	contributed to the conception and design, drafting of the manuscript or revising it for critical important intellectual content	contributed to the conception and design, drafting of the manuscript or revising it for critical important intellectual content	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
6078121	30094283	QLH	2	led the drafting of the manuscript and revising it for critical important intellectual content	led the drafting of the manuscript and revising it for critical important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6078121	30094283	SM	2	contributed to the conception and design, drafting of the manuscript or revising it for critical important intellectual content	contributed to the conception and design, drafting of the manuscript or revising it for critical important intellectual content	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
6078121	30094283	ST	2	led the drafting of the manuscript and revising it for critical important intellectual content|obtained funding and was responsible for supervision of all activities	led the drafting of the manuscript and revising it for critical important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6078121	30094283	ST	2	led the drafting of the manuscript and revising it for critical important intellectual content|obtained funding and was responsible for supervision of all activities	obtained funding and was responsible for supervision of all activities	-	Funding acquisition|Supervision	YES
6078121	30094283	YV	2	contributed to the conception and design, drafting of the manuscript or revising it for critical important intellectual content	contributed to the conception and design, drafting of the manuscript or revising it for critical important intellectual content	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
5338720	28289541	Henrique Morais	7	Conception and design of the study, acquisition of data, analysis and interpretation of data, drafting the article, revising it critically for important intellectual content, final approval of the version to be submitted. Jessica Neves, Hugo Maciel Ribeiro, Marta Ferreira	Conception and design of the study, acquisition of data, analysis and interpretation of data, drafting the article, revising it critically for important intellectual content, final approval of the version to be submitted. Jessica Neves, Hugo Maciel Ribeiro, Marta Ferreira	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5338720	28289541	Lucilia Conceicao	7	Revising it critically for important intellectual content, final approval of the version to be published	Revising it critically for important intellectual content, final approval of the version to be published	Wrote the paper	Writing - Review & Editing	YES
5338720	28289541	Narcisa Guimaraes	7	Analysis and interpretation of data, revising it critically for important intellectual content, final approval of the version to be published. Nuno Azenha, Raquel Dias, Alice Fonseca	Analysis and interpretation of data, revising it critically for important intellectual content, final approval of the version to be published. Nuno Azenha, Raquel Dias, Alice Fonseca	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4796775	26989062	All authors	2	contributed to revisions of the manuscripts and approved the final version for publication	contributed to revisions of the manuscripts and approved the final version for publication	Wrote the paper	Writing - Review & Editing	YES
4796775	26989062	CXS	2	conducted the data analysis, interpreted the results and prepared the report for publication	conducted the data analysis, interpreted the results and prepared the report for publication	Analyzed the data	Formal analysis	YES
4796775	26989062	DL	2	collected the data	collected the data	Performed the experiments	Investigation	YES
4796775	26989062	LW	2	collected the data	collected the data	Performed the experiments	Investigation	YES
4796775	26989062	RB	2	conducted the data analysis, interpreted the results and prepared the report for publication	conducted the data analysis, interpreted the results and prepared the report for publication	Analyzed the data	Formal analysis	YES
4796775	26989062	RD	2	conducted the data analysis, interpreted the results and prepared the report for publication	conducted the data analysis, interpreted the results and prepared the report for publication	Analyzed the data	Formal analysis	YES
4796775	26989062	WG	2	participated in the design and planning of the study|conducted the data analysis, interpreted the results and prepared the report for publication	participated in the design and planning of the study	Conceived and designed the experiments	Methodology	YES
4796775	26989062	WG	2	participated in the design and planning of the study|conducted the data analysis, interpreted the results and prepared the report for publication	conducted the data analysis, interpreted the results and prepared the report for publication	Analyzed the data	Formal analysis	YES
4796775	26989062	YC	2	participated in the design and planning of the study|conducted the data analysis, interpreted the results and prepared the report for publication	participated in the design and planning of the study	Conceived and designed the experiments	Methodology	YES
4796775	26989062	YC	2	participated in the design and planning of the study|conducted the data analysis, interpreted the results and prepared the report for publication	conducted the data analysis, interpreted the results and prepared the report for publication	Analyzed the data	Formal analysis	YES
4796775	26989062	ZW	2	participated in the design and planning of the study|conducted the data analysis, interpreted the results and prepared the report for publication	participated in the design and planning of the study	Conceived and designed the experiments	Methodology	YES
4796775	26989062	ZW	2	participated in the design and planning of the study|conducted the data analysis, interpreted the results and prepared the report for publication	conducted the data analysis, interpreted the results and prepared the report for publication	Analyzed the data	Formal analysis	YES
4405441	25897955	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405441	25897955	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405441	25897955	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405441	25897955	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405441	25897955	EC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405441	25897955	FC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4405441	25897955	FC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405441	25897955	FG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405441	25897955	FM	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405441	25897955	GF	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405441	25897955	GT	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405441	25897955	GT	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405441	25897955	LI	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405441	25897955	MA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405441	25897955	MA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405441	25897955	MA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405441	25897955	ML	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405441	25897955	ML	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405441	25897955	ML	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405441	25897955	MM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405441	25897955	RS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4405441	25897955	RS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5874553	29389850	Marketa Marvanova	PLoS52	conceived and designed the experiments|performed the experiments|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5874553	29389850	Marketa Marvanova	PLoS52	conceived and designed the experiments|performed the experiments|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5874553	29389850	Marketa Marvanova	PLoS52	conceived and designed the experiments|performed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5874553	29389850	Paul Jacob Henkel	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5874553	29389850	Paul Jacob Henkel	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5874553	29389850	Paul Jacob Henkel	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5874553	29389850	Paul Jacob Henkel	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6240223	30445984	All authors	2	provided critical inputs for the writing|read and approved the final manuscript	provided critical inputs for the writing	Wrote the paper	-	YES
6240223	30445984	All authors	2	provided critical inputs for the writing|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6240223	30445984	GM	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6240223	30445984	KC	2	were responsible for data collection training, data collection, and data entry|analyzed data and interpreted the findings|wrote the manuscript	were responsible for data collection training, data collection, and data entry	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
6240223	30445984	KC	2	were responsible for data collection training, data collection, and data entry|analyzed data and interpreted the findings|wrote the manuscript	analyzed data and interpreted the findings	Analyzed the data	Formal analysis	YES
6240223	30445984	KC	2	were responsible for data collection training, data collection, and data entry|analyzed data and interpreted the findings|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6240223	30445984	PC	2	were responsible for data collection training, data collection, and data entry	were responsible for data collection training, data collection, and data entry	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
6240223	30445984	RS	2	analyzed data and interpreted the findings|wrote the manuscript	analyzed data and interpreted the findings	Analyzed the data	Formal analysis	YES
6240223	30445984	RS	2	analyzed data and interpreted the findings|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6240223	30445984	ST	2	conceived the study|were responsible for data collection training, data collection, and data entry	conceived the study	Conceived and designed the experiments	Conceptualization	YES
6240223	30445984	ST	2	conceived the study|were responsible for data collection training, data collection, and data entry	were responsible for data collection training, data collection, and data entry	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
6240223	30445984	SY	2	conceived the study|analyzed data and interpreted the findings|wrote the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
6240223	30445984	SY	2	conceived the study|analyzed data and interpreted the findings|wrote the manuscript	analyzed data and interpreted the findings	Analyzed the data	Formal analysis	YES
6240223	30445984	SY	2	conceived the study|analyzed data and interpreted the findings|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6240223	30445984	VK	2	conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
6395457	30820700	All authors	2	contributed to the initial conception and design of the study|contributed to the editing of the final draft|read and approved the final manuscript|contributed to and approved the final manuscript and gave their consent for publication	contributed to the initial conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6395457	30820700	All authors	2	contributed to the initial conception and design of the study|contributed to the editing of the final draft|read and approved the final manuscript|contributed to and approved the final manuscript and gave their consent for publication	contributed to the editing of the final draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6395457	30820700	All authors	2	contributed to the initial conception and design of the study|contributed to the editing of the final draft|read and approved the final manuscript|contributed to and approved the final manuscript and gave their consent for publication	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6395457	30820700	All authors	2	contributed to the initial conception and design of the study|contributed to the editing of the final draft|read and approved the final manuscript|contributed to and approved the final manuscript and gave their consent for publication	contributed to and approved the final manuscript and gave their consent for publication	Wrote the paper	Writing - Review & Editing	YES
6395457	30820700	CG	2	did the initial data analysis	did the initial data analysis	Analyzed the data	Formal analysis	YES
6395457	30820700	CMO	2	did the initial data analysis	did the initial data analysis	Analyzed the data	Formal analysis	YES
6395457	30820700	CSJ	2	did the initial data analysis	did the initial data analysis	Analyzed the data	Formal analysis	YES
6395457	30820700	DVA	2	did the initial data analysis	did the initial data analysis	Analyzed the data	Formal analysis	YES
6395457	30820700	Danish Health Authorities	2	but restrictions apply to the availability of these data, which were used under license for the current study, and so are not publicly available	but restrictions apply to the availability of these data, which were used under license for the current study, and so are not publicly available	-	-	NO
6395457	30820700	LHL	2	did the initial data analysis	did the initial data analysis	Analyzed the data	Formal analysis	YES
6395457	30820700	Protection Agency	2	approved the use of the data	approved the use of the data	-	-	NO
6395457	30820700	REN	2	completed the first draft of the manuscript and tables	completed the first draft of the manuscript and tables	Wrote the paper	Writing - Original Draft	YES
6395457	30820700	SG	2	did the initial data analysis	did the initial data analysis	Analyzed the data	Formal analysis	YES
6395457	30820700	The Danish Data	2	approved the use of the data	approved the use of the data	-	-	NO
5539243	28824678	CdK	PLoS52	read and commented on the manuscript	read and commented on the manuscript	-	-	NO
5539243	28824678	ES	PLoS52	conceived the study|performed experiments|analyzed the data|read and commented on the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5539243	28824678	ES	PLoS52	conceived the study|performed experiments|analyzed the data|read and commented on the manuscript	performed experiments	Performed the experiments	Investigation	YES
5539243	28824678	ES	PLoS52	conceived the study|performed experiments|analyzed the data|read and commented on the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5539243	28824678	ES	PLoS52	conceived the study|performed experiments|analyzed the data|read and commented on the manuscript	read and commented on the manuscript	-	-	NO
5539243	28824678	HD	PLoS52	performed experiments|analyzed the data|read and commented on the manuscript	performed experiments	Performed the experiments	Investigation	YES
5539243	28824678	HD	PLoS52	performed experiments|analyzed the data|read and commented on the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5539243	28824678	HD	PLoS52	performed experiments|analyzed the data|read and commented on the manuscript	read and commented on the manuscript	-	-	NO
5539243	28824678	JvM	PLoS52	read and commented on the manuscript	read and commented on the manuscript	-	-	NO
5539243	28824678	LS	PLoS52	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5539243	28824678	MH	PLoS52	read and commented on the manuscript	read and commented on the manuscript	-	-	NO
5539243	28824678	RS	PLoS52	conceived the study|read and commented on the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5539243	28824678	RS	PLoS52	conceived the study|read and commented on the manuscript	read and commented on the manuscript	-	-	NO
5539243	28824678	SA	PLoS52	conceived the study|performed experiments|analyzed the data|wrote the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5539243	28824678	SA	PLoS52	conceived the study|performed experiments|analyzed the data|wrote the manuscript	performed experiments	Performed the experiments	Investigation	YES
5539243	28824678	SA	PLoS52	conceived the study|performed experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5539243	28824678	SA	PLoS52	conceived the study|performed experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5286776	28143400	A. Gadaleta	2	designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
5286776	28143400	A. Giancaspro	2	performed the research and analyzed the data	performed the research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5286776	28143400	AB	2	designed the research|wrote the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
5286776	28143400	AB	2	designed the research|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5286776	28143400	AMM	2	performed the research and analyzed the data	performed the research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5286776	28143400	DN	2	performed the research and analyzed the data	performed the research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5286776	28143400	GM	2	performed the research and analyzed the data	performed the research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5286776	28143400	IM	2	designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
5286776	28143400	KH	2	performed the research and analyzed the data	performed the research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5286776	28143400	MLL	2	performed the research and analyzed the data	performed the research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5286776	28143400	NP	2	performed the research and analyzed the data	performed the research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5286776	28143400	PC	2	designed the research|wrote the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
5286776	28143400	PC	2	designed the research|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5286776	28143400	PDV	2	performed the research and analyzed the data	performed the research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5286776	28143400	RS	2	performed the research and analyzed the data	performed the research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5874554	29389869	Abdallah Adlan	PLoS52	interpreted the results	interpreted the results	Analyzed the data	Formal analysis	YES
5874554	29389869	Arwa Aldeeri	PLoS52	interpreted the results|wrote the paper	interpreted the results	Analyzed the data	Formal analysis	YES
5874554	29389869	Arwa Aldeeri	PLoS52	interpreted the results|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5874554	29389869	Haya Alzaid	PLoS52	interpreted the results	interpreted the results	Analyzed the data	Formal analysis	YES
5874554	29389869	Naila Shaheen	PLoS52	interpreted the results	interpreted the results	Analyzed the data	Formal analysis	YES
5874554	29389869	Renad Alshunaiber	PLoS52	interpreted the results	interpreted the results	Analyzed the data	Formal analysis	YES
5874554	29389869	Shahad Meaigel	PLoS52	interpreted the results	interpreted the results	Analyzed the data	Formal analysis	YES
4800379	26996992	All authors	PLoS52	interpreted the data|critically revised the article and approved the final version of the manuscript	interpreted the data	Analyzed the data	Formal analysis	YES
4800379	26996992	All authors	PLoS52	interpreted the data|critically revised the article and approved the final version of the manuscript	critically revised the article and approved the final version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4800379	26996992	BES	PLoS52	conceived and designed the study|contributed to data collection and management|analyzed the data|drafted the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4800379	26996992	BES	PLoS52	conceived and designed the study|contributed to data collection and management|analyzed the data|drafted the manuscript	contributed to data collection and management	Performed the experiments	Investigation	YES
4800379	26996992	BES	PLoS52	conceived and designed the study|contributed to data collection and management|analyzed the data|drafted the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
4800379	26996992	BES	PLoS52	conceived and designed the study|contributed to data collection and management|analyzed the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4800379	26996992	BG	PLoS52	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4800379	26996992	CC	PLoS52	conceived and designed the study|contributed to data collection and management|drafted the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4800379	26996992	CC	PLoS52	conceived and designed the study|contributed to data collection and management|drafted the manuscript	contributed to data collection and management	Performed the experiments	Investigation	YES
4800379	26996992	CC	PLoS52	conceived and designed the study|contributed to data collection and management|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4800379	26996992	CMG	PLoS52	conceived and designed the study|contributed to data collection and management|analyzed the data|drafted the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4800379	26996992	CMG	PLoS52	conceived and designed the study|contributed to data collection and management|analyzed the data|drafted the manuscript	contributed to data collection and management	Performed the experiments	Investigation	YES
4800379	26996992	CMG	PLoS52	conceived and designed the study|contributed to data collection and management|analyzed the data|drafted the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
4800379	26996992	CMG	PLoS52	conceived and designed the study|contributed to data collection and management|analyzed the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4800379	26996992	JRK	PLoS52	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4800379	26996992	MJG	PLoS52	contributed to data collection and management|drafted the manuscript	contributed to data collection and management	Performed the experiments	Investigation	YES
4800379	26996992	MJG	PLoS52	contributed to data collection and management|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4800379	26996992	PC	PLoS52	conceived and designed the study|contributed to data collection and management|drafted the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4800379	26996992	PC	PLoS52	conceived and designed the study|contributed to data collection and management|drafted the manuscript	contributed to data collection and management	Performed the experiments	Investigation	YES
4800379	26996992	PC	PLoS52	conceived and designed the study|contributed to data collection and management|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4800379	26996992	RDM	PLoS52	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405470	25898014	AB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405470	25898014	AB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405470	25898014	AD	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Supporting community facilitators during the study	Performed the experiments	Performed the experiments	Investigation	YES
4405470	25898014	AD	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Supporting community facilitators during the study	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405470	25898014	AD	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Supporting community facilitators during the study	Supporting community facilitators during the study	-	-	NO
4405470	25898014	CCB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405470	25898014	CCB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405470	25898014	CCB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405470	25898014	CCB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405470	25898014	CR	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Supporting community facilitators during the study	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405470	25898014	CR	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Supporting community facilitators during the study	Performed the experiments	Performed the experiments	Investigation	YES
4405470	25898014	CR	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Supporting community facilitators during the study	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405470	25898014	CR	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Supporting community facilitators during the study	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405470	25898014	CR	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Supporting community facilitators during the study	Supporting community facilitators during the study	-	-	NO
4405470	25898014	HRW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Supporting community facilitators during the study	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405470	25898014	HRW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Supporting community facilitators during the study	Analyzed the data	Analyzed the data	Formal analysis	YES
4405470	25898014	HRW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Supporting community facilitators during the study	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405470	25898014	HRW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Supporting community facilitators during the study	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405470	25898014	HRW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Supporting community facilitators during the study	Supporting community facilitators during the study	-	-	NO
4405470	25898014	JCP	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405470	25898014	JCP	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405470	25898014	JH	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405470	25898014	JH	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405470	25898014	RMAP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405470	25898014	RMAP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405470	25898014	RMAP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5342983	28316781	Baltazar Gonzalez Andrade	7	Data collection, patient care	Data collection, patient care	Performed the experiments	Investigation	YES
5342983	28316781	German A. Soto-Galindo	7	Data collection, writing, editing and submission	Data collection, writing, editing and submission	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5342983	28316781	Jesus Villegas Gonzalez	7	Data collection, patient care	Data collection, patient care	Performed the experiments	Investigation	YES
5342983	28316781	Jose Luis Trevino	7	Data collection and analysis, patient care, writing, editing and submission	Data collection and analysis, patient care, writing, editing and submission	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
5342983	28316781	Marco A. Mario	7	Data collection, patient care	Data collection, patient care	Performed the experiments	Investigation	YES
5342983	28316781	Mendez Saenz	7	Data collection and analysis, writing. Vicente J	Data collection and analysis, writing. Vicente J	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation	YES
5342983	28316781	Miguel Angel Linan	7	Data collection, patient care	Data collection, patient care	Performed the experiments	Investigation	YES
5342983	28316781	Villagomez Ortiz	7	Data collection, patient care	Data collection, patient care	Performed the experiments	Investigation	YES
4486297	26161396	F. Qiu	2	contributed equally to this work	contributed equally to this work	-	-	NO
4486297	26161396	Y. Liu	2	contributed equally to this work	contributed equally to this work	-	-	NO
6247671	30458874	AKM	1	The methodology was designed by	The methodology was designed by	Conceived and designed the experiments|Performed the experiments	Methodology	YES
6247671	30458874	CZ	1	The methodology was designed by	The methodology was designed by	Conceived and designed the experiments|Performed the experiments	Methodology	YES
6247671	30458874	ESS	1	The methodology was designed by	The methodology was designed by	Conceived and designed the experiments|Performed the experiments	Methodology	YES
6247671	30458874	FCM	1	The methodology was designed by	The methodology was designed by	Conceived and designed the experiments|Performed the experiments	Methodology	YES
6397716	30826916	All	2	participants gave oral and written informed consent to participate	participants gave oral and written informed consent to participate	Wrote the paper	Writing - Original Draft	YES
6397716	30826916	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6397716	30826916	DVS	2	contributed and supervised throughout data analysis|have critically revised and substantially contributed throughout the compilation of the manuscript	contributed and supervised throughout data analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources|Supervision	YES
6397716	30826916	DVS	2	contributed and supervised throughout data analysis|have critically revised and substantially contributed throughout the compilation of the manuscript	have critically revised and substantially contributed throughout the compilation of the manuscript	Wrote the paper	Writing - Review & Editing	YES
6397716	30826916	KS	2	provided critical and clinical input in the analytic process|have critically revised and substantially contributed throughout the compilation of the manuscript	provided critical and clinical input in the analytic process	-	-	NO
6397716	30826916	KS	2	provided critical and clinical input in the analytic process|have critically revised and substantially contributed throughout the compilation of the manuscript	have critically revised and substantially contributed throughout the compilation of the manuscript	Wrote the paper	Writing - Review & Editing	YES
6397716	30826916	T.A.	2	did not pursue themes as much as would have been optimal for the research purpose|shared clinically relevant information with the participants mental health workers	did not pursue themes as much as would have been optimal for the research purpose	-	-	NO
6397716	30826916	T.A.	2	did not pursue themes as much as would have been optimal for the research purpose|shared clinically relevant information with the participants mental health workers	shared clinically relevant information with the participants mental health workers	Performed the experiments	Investigation	YES
6397716	30826916	TMSA	2	performed recruitment and data collection and was the main coder in the analysis|is the primary author in the writing of the manuscript	performed recruitment and data collection and was the main coder in the analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6397716	30826916	TMSA	2	performed recruitment and data collection and was the main coder in the analysis|is the primary author in the writing of the manuscript	is the primary author in the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
6397716	30826916	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5358939	28348733	All	2	the authors	the authors	-	-	NO
5358939	28348733	Jiichiro Sasaki	2	contributed to the study design, data collections, data analysis and writing of the manuscript	contributed to the study design, data collections, data analysis and writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
5358939	28348733	Masahiko Watanabe	2	contributed to the study design, data collections, data analysis and writing of the manuscript	contributed to the study design, data collections, data analysis and writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
5358939	28348733	Shinzo Torii	2	contributed to the study design, data collections, data analysis and writing of the manuscript	contributed to the study design, data collections, data analysis and writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
5358939	28348733	Takatoshi Nakamura	2	contributed to the study design, data collections, data analysis and writing of the manuscript	contributed to the study design, data collections, data analysis and writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
5358939	28348733	Takeo Sato	2	contributed to the study design, data collections, data analysis and writing of the manuscript	contributed to the study design, data collections, data analysis and writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
5358939	28348733	Yasushi Asari	2	contributed to the study design, data collections, data analysis and writing of the manuscript	contributed to the study design, data collections, data analysis and writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
3548096	22732767	ISM	2	were all involved in concept/design, data analysis and interpretation, drafting, critical revision and approval of the article	were all involved in concept/design, data analysis and interpretation, drafting, critical revision and approval of the article	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
3548096	22732767	LW	2	were all involved in concept/design, data analysis and interpretation, drafting, critical revision and approval of the article	were all involved in concept/design, data analysis and interpretation, drafting, critical revision and approval of the article	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
3548096	22732767	TMM	2	were all involved in concept/design, data analysis and interpretation, drafting, critical revision and approval of the article	were all involved in concept/design, data analysis and interpretation, drafting, critical revision and approval of the article	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5874555	29401733	Both authors	2	contributed to the teaching of concepts, application of the described activity, and preparation of the manuscript	contributed to the teaching of concepts, application of the described activity, and preparation of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4803835	27005750	All the authors	2	critically appraised the manuscript and approved the final version of the manuscript for publication	critically appraised the manuscript and approved the final version of the manuscript for publication	-	-	NO
4803835	27005750	IM	2	conceived and designed the study|performed data abstraction and analyzed the data|wrote the draft manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4803835	27005750	IM	2	conceived and designed the study|performed data abstraction and analyzed the data|wrote the draft manuscript	performed data abstraction and analyzed the data	Analyzed the data	Formal analysis	YES
4803835	27005750	IM	2	conceived and designed the study|performed data abstraction and analyzed the data|wrote the draft manuscript	wrote the draft manuscript	Wrote the paper	Writing - Original Draft	YES
4803835	27005750	MA	2	performed data abstraction and analyzed the data	performed data abstraction and analyzed the data	Analyzed the data	Formal analysis	YES
4405476	25897840	AM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405476	25897840	AM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405476	25897840	AM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405476	25897840	FA	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405476	25897840	FA	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405476	25897840	GB	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405476	25897840	KF	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405476	25897840	KF	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405476	25897840	MB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405476	25897840	MB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405476	25897840	MB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405476	25897840	ML	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405476	25897840	ML	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405476	25897840	TO	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405476	25897840	TO	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405476	25897840	YB	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405476	25897840	YB	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5539759	28824673	HF	2	conceptualized the idea and revised the manuscript	conceptualized the idea and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5539759	28824673	MW	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5539759	28824673	NS	2	wrote this manuscript|conceptualized the idea and revised the manuscript	wrote this manuscript	Wrote the paper	Writing - Original Draft	YES
5539759	28824673	NS	2	wrote this manuscript|conceptualized the idea and revised the manuscript	conceptualized the idea and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5539759	28824673	ST	2	wrote this manuscript|performed experiments|collected data and carried out all analyses	wrote this manuscript	Wrote the paper	Writing - Original Draft	YES
5539759	28824673	ST	2	wrote this manuscript|performed experiments|collected data and carried out all analyses	performed experiments	Performed the experiments	Investigation	YES
5539759	28824673	ST	2	wrote this manuscript|performed experiments|collected data and carried out all analyses	collected data and carried out all analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5539759	28824673	WW	2	performed experiments|collected data and carried out all analyses	performed experiments	Performed the experiments	Investigation	YES
5539759	28824673	WW	2	performed experiments|collected data and carried out all analyses	collected data and carried out all analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5288901	28148242	HH	PLoS52	conducted the experiments|wrote the paper	conducted the experiments	Performed the experiments	Investigation	YES
5288901	28148242	HH	PLoS52	conducted the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5288901	28148242	HT	PLoS52	conducted the experiments	conducted the experiments	Performed the experiments	Investigation	YES
5288901	28148242	KSakamoto	PLoS52	conducted the experiments	conducted the experiments	Performed the experiments	Investigation	YES
5288901	28148242	KSato	PLoS52	designed the research|wrote the paper	designed the research	Conceived and designed the experiments	Methodology	YES
5288901	28148242	KSato	PLoS52	designed the research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5288901	28148242	RT	PLoS52	designed the research|wrote the paper	designed the research	Conceived and designed the experiments	Methodology	YES
5288901	28148242	RT	PLoS52	designed the research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4486308	26161399	All authors	2	critically reviewed and revised the paper and approved the final version of it as submitted	critically reviewed and revised the paper and approved the final version of it as submitted	Wrote the paper	Writing - Review & Editing	YES
4486308	26161399	Audrius Dedele	2	undertook the environmental exposure modelling	undertook the environmental exposure modelling	Performed the experiments	Investigation|Methodology	YES
4486308	26161399	Christopher Gidlow	2	designed the experimental study and critically reviewed the paper	designed the experimental study and critically reviewed the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
4486308	26161399	Egle Tamuleviciute-Prasciene	2	participated in the experimental study and the drafting of the methods	participated in the experimental study and the drafting of the methods	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4486308	26161399	Indre Ceponiene	2	participated in the experimental study and assisted with the writing of the paper	participated in the experimental study and assisted with the writing of the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4486308	26161399	Jone Vencloviene	2	performed statistical analysis and assisted with interpretation	performed statistical analysis and assisted with interpretation	Analyzed the data	Formal analysis	YES
4486308	26161399	Marc Jones	2	contributed to the design of the study	contributed to the design of the study	Conceived and designed the experiments	Methodology	YES
4486308	26161399	Mark J. Nieuwenhuijsen	2	conceptualized and supervised the study and critically reviewed the paper	conceptualized and supervised the study and critically reviewed the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Supervision|Writing - Review & Editing	YES
4486308	26161399	Raimondas Kubilius	2	participated in the randomization of study participants and in clinical investigations	participated in the randomization of study participants and in clinical investigations	Performed the experiments	Investigation	YES
4486308	26161399	Regina Grazuleviciene	2	conceived the idea and was the lead writer	conceived the idea and was the lead writer	Conceived and designed the experiments|Wrote the paper	Conceptualization	YES
4486308	26161399	Tomas Grazulevicius	2	drafted the tables and assisted with the writing of the paper	drafted the tables and assisted with the writing of the paper	Wrote the paper	Writing - Original Draft	YES
4486308	26161399	Vytautas Grizas	2	participated in the clinical investigations	participated in the clinical investigations	Performed the experiments	Investigation	YES
5369264	28386393	Amanda Mercado	2	data collections	data collections	Performed the experiments	Investigation	YES
5369264	28386393	Brijen J. Shah	2	study design, writing	study design, writing	Conceived and designed the experiments|Wrote the paper	Methodology	YES
5369264	28386393	David Muller	2	data analysis, writing	data analysis, writing	Analyzed the data|Wrote the paper	Formal analysis	YES
5369264	28386393	Gaber Badran	2	study design, data collections, data analysis	study design, data collections, data analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5369264	28386393	MD	2	study design, data collections, data analysis, writing|study design, writing|study design, data collections, data analysis|data analysis, writing|data analysis, writing	study design, data collections, data analysis, writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology	YES
5369264	28386393	MD	2	study design, data collections, data analysis, writing|study design, writing|study design, data collections, data analysis|data analysis, writing|data analysis, writing	study design, writing	Conceived and designed the experiments|Wrote the paper	Methodology	YES
5369264	28386393	MD	2	study design, data collections, data analysis, writing|study design, writing|study design, data collections, data analysis|data analysis, writing|data analysis, writing	study design, data collections, data analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5369264	28386393	MD	2	study design, data collections, data analysis, writing|study design, writing|study design, data collections, data analysis|data analysis, writing|data analysis, writing	data analysis, writing	Analyzed the data|Wrote the paper	Formal analysis	YES
5369264	28386393	MD	2	study design, data collections, data analysis, writing|study design, writing|study design, data collections, data analysis|data analysis, writing|data analysis, writing	data analysis, writing	Analyzed the data|Wrote the paper	Formal analysis	YES
5369264	28386393	MHPE	2	data analysis, writing	data analysis, writing	Analyzed the data|Wrote the paper	Formal analysis	YES
5369264	28386393	Michael Leitman	2	study design, data collections, data analysis, writing	study design, data collections, data analysis, writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology	YES
5369264	28386393	Reena Karani	2	data analysis, writing	data analysis, writing	Analyzed the data|Wrote the paper	Formal analysis	YES
5369264	28386393	Scott H. Barnett	2	study design, data collections, data analysis	study design, data collections, data analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
6260781	30477526	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
3548110	22706617	All authors	2	revised the manuscript critically for important intellectual content and read and approved the final manuscript	revised the manuscript critically for important intellectual content and read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
3548110	22706617	Anna-Carin Berggren	2	participated in the study design and coordination	participated in the study design and coordination	Conceived and designed the experiments	Methodology|Project administration	YES
3548110	22706617	Helen Johnson	2	performed the pk analysis	performed the pk analysis	Performed the experiments	Investigation	YES
3548110	22706617	Ingegerd Odar-Cederlof	2	initiated the study and acted as pharmacological advisor during the study design	initiated the study and acted as pharmacological advisor during the study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
3548110	22706617	Jan Persson	2	participated in the study design and was the senior author	participated in the study design and was the senior author	Conceived and designed the experiments	Methodology	YES
3548110	22706617	Nabil Al-Tawil	2	was the principal investigator for the study and participated in study design and conduct	was the principal investigator for the study and participated in study design and conduct	Conceived and designed the experiments|Performed the experiments	Conceptualization|Funding acquisition|Investigation|Methodology	YES
6435763	30915592	AHY	2	contributed equally to the conceptualization and writing of this manuscript	contributed equally to the conceptualization and writing of this manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
6435763	30915592	Both authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6435763	30915592	SJ	2	contributed equally to the conceptualization and writing of this manuscript|declares no competing interests	contributed equally to the conceptualization and writing of this manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
6435763	30915592	SJ	2	contributed equally to the conceptualization and writing of this manuscript|declares no competing interests	declares no competing interests	-	-	NO
5874556	29419807	Caroline Hall	PLoS52	performed the interviews|analyzed the data|wrote the paper	performed the interviews	Performed the experiments	Investigation	YES
5874556	29419807	Caroline Hall	PLoS52	performed the interviews|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5874556	29419807	Caroline Hall	PLoS52	performed the interviews|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5874556	29419807	Ella Scacchia	PLoS52	performed the interviews|analyzed the data|wrote the paper	performed the interviews	Performed the experiments	Investigation	YES
5874556	29419807	Ella Scacchia	PLoS52	performed the interviews|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5874556	29419807	Ella Scacchia	PLoS52	performed the interviews|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5874556	29419807	Emma Ioppolo	PLoS52	performed the interviews|analyzed the data|wrote the paper	performed the interviews	Performed the experiments	Investigation	YES
5874556	29419807	Emma Ioppolo	PLoS52	performed the interviews|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5874556	29419807	Emma Ioppolo	PLoS52	performed the interviews|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5874556	29419807	Helen Wood	PLoS52	conceived and designed the study|analyzed the data|wrote the paper	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5874556	29419807	Helen Wood	PLoS52	conceived and designed the study|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5874556	29419807	Helen Wood	PLoS52	conceived and designed the study|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5874556	29419807	Renee Ioppolo	PLoS52	performed the interviews|analyzed the data|wrote the paper	performed the interviews	Performed the experiments	Investigation	YES
5874556	29419807	Renee Ioppolo	PLoS52	performed the interviews|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5874556	29419807	Renee Ioppolo	PLoS52	performed the interviews|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5874556	29419807	Rhonda Clifford	PLoS52	provided input into the writing of the paper	provided input into the writing of the paper	Wrote the paper	Writing - Original Draft	YES
5874556	29419807	Sajni Gudka	PLoS52	conceived and designed the study|analyzed the data	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5874556	29419807	Sajni Gudka	PLoS52	conceived and designed the study|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5291953	28158971	KK	2	participated in the design of the study carried out the library preparation, sequencing, analysis of the data and drafted the manuscript	participated in the design of the study carried out the library preparation, sequencing, analysis of the data and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5291953	28158971	SL	2	conceived of the study, and participated in its design and coordination and helped to draft the manuscript	conceived of the study, and participated in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
4405478	25898260	DS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4405478	25898260	DS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405478	25898260	HT	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405478	25898260	HU	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4405478	25898260	KS	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405478	25898260	KS	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405478	25898260	KW	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405478	25898260	KW	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405478	25898260	MH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405478	25898260	MK	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405478	25898260	MK	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405478	25898260	MU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405478	25898260	MU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405478	25898260	MU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405478	25898260	MU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405478	25898260	MU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405478	25898260	NS	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4405478	25898260	TO	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4405478	25898260	TO	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405478	25898260	TS	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4405478	25898260	TT	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405478	25898260	YI	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405478	25898260	YI	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405478	25898260	YS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405478	25898260	YS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405478	25898260	YS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405478	25898260	YS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405478	25898260	YS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4808141	27015798	CAB	2	were involved in the conduct of the field study	were involved in the conduct of the field study	Performed the experiments	Investigation	YES
4808141	27015798	DA	2	were involved in the conduct of the field study	were involved in the conduct of the field study	Performed the experiments	Investigation	YES
4808141	27015798	DD	2	contributed to the design, data analysis and interpretation|drafted the first report of the manuscript, which all authors subsequently reviewed, edited and approved|were involved in the conduct of the field study	contributed to the design, data analysis and interpretation	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
4808141	27015798	DD	2	contributed to the design, data analysis and interpretation|drafted the first report of the manuscript, which all authors subsequently reviewed, edited and approved|were involved in the conduct of the field study	drafted the first report of the manuscript, which all authors subsequently reviewed, edited and approved	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4808141	27015798	DD	2	contributed to the design, data analysis and interpretation|drafted the first report of the manuscript, which all authors subsequently reviewed, edited and approved|were involved in the conduct of the field study	were involved in the conduct of the field study	Performed the experiments	Investigation	YES
4808141	27015798	DY	2	were involved in the conduct of the field study	were involved in the conduct of the field study	Performed the experiments	Investigation	YES
4808141	27015798	MAF	2	were involved in the conduct of the field study	were involved in the conduct of the field study	Performed the experiments	Investigation	YES
4808141	27015798	MC	2	were involved in the conduct of the field study	were involved in the conduct of the field study	Performed the experiments	Investigation	YES
4808141	27015798	MTK	2	were co-investigators of the monod project and contributed to data interpretation|were involved in the conduct of the field study	were co-investigators of the monod project and contributed to data interpretation	Analyzed the data	Formal analysis	YES
4808141	27015798	MTK	2	were co-investigators of the monod project and contributed to data interpretation|were involved in the conduct of the field study	were involved in the conduct of the field study	Performed the experiments	Investigation	YES
4808141	27015798	NM	2	were co-investigators of the monod project and contributed to data interpretation	were co-investigators of the monod project and contributed to data interpretation	Analyzed the data	Formal analysis	YES
4808141	27015798	PL	2	were co-investigators of the monod project and contributed to data interpretation	were co-investigators of the monod project and contributed to data interpretation	Analyzed the data	Formal analysis	YES
4808141	27015798	RS	2	were co-investigators of the monod project and contributed to data interpretation	were co-investigators of the monod project and contributed to data interpretation	Analyzed the data	Formal analysis	YES
4808141	27015798	VA	2	were co-investigators of the monod project and contributed to data interpretation	were co-investigators of the monod project and contributed to data interpretation	Analyzed the data	Formal analysis	YES
4808141	27015798	VL	2	were co-investigators of the monod project and contributed to data interpretation|contributed to the design, data analysis and interpretation|drafted the first report of the manuscript, which all authors subsequently reviewed, edited and approved	were co-investigators of the monod project and contributed to data interpretation	Analyzed the data	Formal analysis	YES
4808141	27015798	VL	2	were co-investigators of the monod project and contributed to data interpretation|contributed to the design, data analysis and interpretation|drafted the first report of the manuscript, which all authors subsequently reviewed, edited and approved	contributed to the design, data analysis and interpretation	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
4808141	27015798	VL	2	were co-investigators of the monod project and contributed to data interpretation|contributed to the design, data analysis and interpretation|drafted the first report of the manuscript, which all authors subsequently reviewed, edited and approved	drafted the first report of the manuscript, which all authors subsequently reviewed, edited and approved	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5369265	28386394	AD	2	the cardiologists	the cardiologists	-	-	NO
5369265	28386394	All authors	2	contributed on paper writing	contributed on paper writing	Wrote the paper	-	YES
5369265	28386394	ERR	2	the cardiologists	the cardiologists	-	-	NO
5539789	28824680	NC	PLoS52	planned and designed the studies|performed experiments|analyzed the data|wrote the manuscript	planned and designed the studies	Conceived and designed the experiments	Conceptualization|Methodology	YES
5539789	28824680	NC	PLoS52	planned and designed the studies|performed experiments|analyzed the data|wrote the manuscript	performed experiments	Performed the experiments	Investigation	YES
5539789	28824680	NC	PLoS52	planned and designed the studies|performed experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5539789	28824680	NC	PLoS52	planned and designed the studies|performed experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5539789	28824680	X-GX	PLoS52	planned and designed the studies|analyzed the data|wrote the manuscript	planned and designed the studies	Conceived and designed the experiments	Conceptualization|Methodology	YES
5539789	28824680	X-GX	PLoS52	planned and designed the studies|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5539789	28824680	X-GX	PLoS52	planned and designed the studies|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5539789	28824680	X-LT	PLoS52	planned and designed the studies|wrote the manuscript	planned and designed the studies	Conceived and designed the experiments	Conceptualization|Methodology	YES
5539789	28824680	X-LT	PLoS52	planned and designed the studies|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6260879	30474565	Both authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6260879	30474565	CF	2	provided critical revision of the manuscript	provided critical revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
6260879	30474565	Gilead Sciences	2	paid to his university	paid to his university	-	-	NO
6260879	30474565	HIV	2	innovation forum	innovation forum	-	-	NO
6260879	30474565	SK	2	wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
6443730	30937561	All authors	2	contributed with conception and writing|read and approved the final manuscript	contributed with conception and writing	Conceived and designed the experiments|Wrote the paper	Conceptualization	YES
6443730	30937561	All authors	2	contributed with conception and writing|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6443730	30937561	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5369852	28377802	Qamaruddin Baloch	2	did all the surgeries	did all the surgeries	Performed the experiments	Investigation	YES
5369852	28377802	Zahid Ali Memon	2	did all the surgeries	did all the surgeries	Performed the experiments	Investigation	YES
4486311	26161412	Xiaomiao Zhao	2	contributed as co-first authors	contributed as co-first authors	-	-	NO
4486311	26161412	Xuelian Tang	2	contributed as co-first authors	contributed as co-first authors	-	-	NO
4405480	25897804	AQ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405480	25897804	EPM	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405480	25897804	EPM	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405480	25897804	MAFG	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4405480	25897804	MRMC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405480	25897804	MRMC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405480	25897804	MRMC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405480	25897804	MRMC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4808692	27018421	Both authors	2	contributed equally to the writing, review and approval of this editorial	contributed equally to the writing, review and approval of this editorial	Wrote the paper	Writing - Review & Editing	YES
5374752	28386396	All authors	5	contributed writing the commentary to the Editor	contributed writing the commentary to the Editor	Wrote the paper	Writing - Review & Editing	YES
5540887	28824682	AP	2	conceived the project and wrote the article with contributions of all the authors	conceived the project and wrote the article with contributions of all the authors	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5540887	28824682	CS	2	performed and designed experiments	performed and designed experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5540887	28824682	DV	2	performed most of the experiments|performed and designed experiments|conceived the project and wrote the article with contributions of all the authors	performed most of the experiments	Performed the experiments	Investigation	YES
5540887	28824682	DV	2	performed most of the experiments|performed and designed experiments|conceived the project and wrote the article with contributions of all the authors	performed and designed experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5540887	28824682	DV	2	performed most of the experiments|performed and designed experiments|conceived the project and wrote the article with contributions of all the authors	conceived the project and wrote the article with contributions of all the authors	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5540887	28824682	LW	2	conceived the project and wrote the article with contributions of all the authors	conceived the project and wrote the article with contributions of all the authors	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5540887	28824682	OK	2	conceived the project and wrote the article with contributions of all the authors	conceived the project and wrote the article with contributions of all the authors	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5540887	28824682	SH	2	performed and designed experiments	performed and designed experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5540887	28824682	TB	2	performed and designed experiments	performed and designed experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4808693	27018422	DD	2	is solely responsible for the authorship of this viewpoint	is solely responsible for the authorship of this viewpoint	-	-	NO
6264043	30497481	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6264043	30497481	DA	2	lead the parent study design and oversee overall study implementation	lead the parent study design and oversee overall study implementation	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Supervision	YES
6264043	30497481	Health Research	2	for their support and funding of this research	for their support and funding of this research	-	Funding acquisition	YES
6264043	30497481	MWB	2	wrote, edited, and finalized the manuscript and led the submission process for this article	wrote, edited, and finalized the manuscript and led the submission process for this article	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6264043	30497481	OG	2	conceptualized the research, analyzed the data and provided overall guidance on methodology development and implementation throughout the course of the study	conceptualized the research, analyzed the data and provided overall guidance on methodology development and implementation throughout the course of the study	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation|Methodology|Supervision	YES
6264043	30497481	PB	2	lead the parent study design and oversee overall study implementation	lead the parent study design and oversee overall study implementation	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Supervision	YES
6264043	30497481	PS	2	collected the cost data during the study intervention period and drafted the methodology and results sections of this article	collected the cost data during the study intervention period and drafted the methodology and results sections of this article	Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
6443746	30937579	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6443746	30937579	Anne Praestegaard	2	for her logistic and laboratory assistance throughout the study	for her logistic and laboratory assistance throughout the study	Performed the experiments	Investigation	YES
6443746	30937579	BP	2	experts within the investigated field, participated with intellectual contributions to the manuscript	experts within the investigated field, participated with intellectual contributions to the manuscript	-	-	NO
6443746	30937579	FKK	2	experts within the investigated field, participated with intellectual contributions to the manuscript	experts within the investigated field, participated with intellectual contributions to the manuscript	-	-	NO
6443746	30937579	KC	2	contributed in the design and overall statistical plan|declare no conflicts of interest	contributed in the design and overall statistical plan	Conceived and designed the experiments|Analyzed the data	Formal analysis	YES
6443746	30937579	KC	2	contributed in the design and overall statistical plan|declare no conflicts of interest	declare no conflicts of interest	-	-	NO
6443746	30937579	KM	2	contributed in the design and overall statistical plan|declare no conflicts of interest	contributed in the design and overall statistical plan	Conceived and designed the experiments|Analyzed the data	Formal analysis	YES
6443746	30937579	KM	2	contributed in the design and overall statistical plan|declare no conflicts of interest	declare no conflicts of interest	-	-	NO
6443746	30937579	LVK	2	contributed in the design and overall statistical plan|also contributed with interpretation of data	contributed in the design and overall statistical plan	Conceived and designed the experiments|Analyzed the data	Formal analysis	YES
6443746	30937579	LVK	2	contributed in the design and overall statistical plan|also contributed with interpretation of data	also contributed with interpretation of data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6443746	30937579	MV	2	contributed in the design and overall statistical plan|also contributed with interpretation of data	contributed in the design and overall statistical plan	Conceived and designed the experiments|Analyzed the data	Formal analysis	YES
6443746	30937579	MV	2	contributed in the design and overall statistical plan|also contributed with interpretation of data	also contributed with interpretation of data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6443746	30937579	RM	2	experts within the investigated field, participated with intellectual contributions to the manuscript	experts within the investigated field, participated with intellectual contributions to the manuscript	-	-	NO
5874558	29495370	Fidelma Corcoran	PLoS52	were involved in patient recruitment	were involved in patient recruitment	Performed the experiments	Investigation	YES
5874558	29495370	Geraldine Scanlon	PLoS52	were involved in patient recruitment	were involved in patient recruitment	Performed the experiments	Investigation	YES
5874558	29495370	J Sahm	PLoS52	conceived and designed the study|analyzed the data|were involved in drafting the manuscript and all authors reviewed and agreed upon the final draft	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5874558	29495370	J Sahm	PLoS52	conceived and designed the study|analyzed the data|were involved in drafting the manuscript and all authors reviewed and agreed upon the final draft	analyzed the data	Analyzed the data	Formal analysis	YES
5874558	29495370	J Sahm	PLoS52	conceived and designed the study|analyzed the data|were involved in drafting the manuscript and all authors reviewed and agreed upon the final draft	were involved in drafting the manuscript and all authors reviewed and agreed upon the final draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5874558	29495370	Marita Barrett	PLoS52	were involved in patient recruitment|undertook data collection	were involved in patient recruitment	Performed the experiments	Investigation	YES
5874558	29495370	Marita Barrett	PLoS52	were involved in patient recruitment|undertook data collection	undertook data collection	Performed the experiments	Investigation	YES
5874558	29495370	Mary Kigathi	PLoS52	were involved in patient recruitment	were involved in patient recruitment	Performed the experiments	Investigation	YES
5292791	28166733	CEF	2	was a major contributor to the study design and was a major contributor to the manuscript	was a major contributor to the study design and was a major contributor to the manuscript	Conceived and designed the experiments	Methodology	YES
5292791	28166733	CSG	2	designed the study, interpreted the results, and wrote the manuscript	designed the study, interpreted the results, and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5292791	28166733	GPW	2	built, analyzed, and interpreted the classifier, generated the figures, created all source code, and wrote the manuscript	built, analyzed, and interpreted the classifier, generated the figures, created all source code, and wrote the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Software|Visualization|Writing - Original Draft	YES
5292791	28166733	RJA	2	performed all experiments, interpreted the classifier, and wrote the manuscript	performed all experiments, interpreted the classifier, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5292791	28166733	SJB	2	interpreted the results and was a major contributor to the manuscript	interpreted the results and was a major contributor to the manuscript	Analyzed the data	Formal analysis	YES
5292791	28166733	YS	2	designed the study, interpreted the results, and wrote the manuscript	designed the study, interpreted the results, and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5374757	28386395	JS	7	writing	writing	Wrote the paper	-	YES
5374757	28386395	PT	7	study design, data collection and analysis, writing	study design, data collection and analysis, writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology	YES
5374757	28386395	RG	7	writing	writing	Wrote the paper	-	YES
5374757	28386395	SC	7	study design, writing	study design, writing	Conceived and designed the experiments|Wrote the paper	Methodology	YES
4405487	25898255	BI	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405487	25898255	BI	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405487	25898255	BI	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405487	25898255	FH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405487	25898255	FH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405487	25898255	FH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405487	25898255	FH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405487	25898255	ID	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4405487	25898255	JMS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405487	25898255	KL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405487	25898255	KL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405487	25898255	KL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405487	25898255	KL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405487	25898255	MR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Guarantor of the work	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405487	25898255	MR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Guarantor of the work	Performed the experiments	Performed the experiments	Investigation	YES
4405487	25898255	MR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Guarantor of the work	Analyzed the data	Analyzed the data	Formal analysis	YES
4405487	25898255	MR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Guarantor of the work	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405487	25898255	MR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Guarantor of the work	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405487	25898255	MR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Guarantor of the work	Guarantor of the work	-	-	NO
4405487	25898255	P. Naredi	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405487	25898255	P. Naredi	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405487	25898255	P. Nilsson	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4405487	25898255	P. Nilsson	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4405487	25898255	P. Nilsson	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405487	25898255	PA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405487	25898255	PA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405487	25898255	PA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405487	25898255	PA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405487	25898255	PNi	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405487	25898255	SD	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405487	25898255	TA	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5540889	28824683	JS	PLoS52	interpreted the results|significantly edited the manuscript	interpreted the results	Analyzed the data	Formal analysis	YES
5540889	28824683	JS	PLoS52	interpreted the results|significantly edited the manuscript	significantly edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5540889	28824683	PP	PLoS52	collected the data|analyzed the data|drafted the manuscript	collected the data	Performed the experiments	Investigation	YES
5540889	28824683	PP	PLoS52	collected the data|analyzed the data|drafted the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5540889	28824683	PP	PLoS52	collected the data|analyzed the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5540889	28824683	The authors	PLoS52	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	Performed the experiments	Investigation	YES
5540889	28824683	VS	PLoS52	collected the data	collected the data	Performed the experiments	Investigation	YES
5540889	28824683	YG	PLoS52	contrived the study|interpreted the results|drafted the manuscript	contrived the study	-	-	NO
5540889	28824683	YG	PLoS52	contrived the study|interpreted the results|drafted the manuscript	interpreted the results	Analyzed the data	Formal analysis	YES
5540889	28824683	YG	PLoS52	contrived the study|interpreted the results|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5376268	28392913	A. P. Perera	7	Study conception and design, statistical analysis - second reviewer	Study conception and design, statistical analysis - second reviewer	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
5376268	28392913	A. Qureshi	7	Writing the paper, data collection - first reviewer	Writing the paper, data collection - first reviewer	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
4405488	25897491	AG	PLoS5	Performed the experiments|Reviewed the final manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4405488	25897491	AG	PLoS5	Performed the experiments|Reviewed the final manuscript	Reviewed the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4405488	25897491	AN	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405488	25897491	CH	PLoS5	Wrote the paper|Reviewed the final manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405488	25897491	CH	PLoS5	Wrote the paper|Reviewed the final manuscript	Reviewed the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4405488	25897491	EL	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Interpreted the results|Reviewed the final manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405488	25897491	EL	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Interpreted the results|Reviewed the final manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4405488	25897491	EL	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Interpreted the results|Reviewed the final manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405488	25897491	EL	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Interpreted the results|Reviewed the final manuscript	Interpreted the results	Analyzed the data	Formal analysis	YES
4405488	25897491	EL	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Interpreted the results|Reviewed the final manuscript	Reviewed the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4405488	25897491	FH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Interpreted the results	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405488	25897491	FH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Interpreted the results	Analyzed the data	Analyzed the data	Formal analysis	YES
4405488	25897491	FH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Interpreted the results	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405488	25897491	FH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Interpreted the results	Interpreted the results	Analyzed the data	Formal analysis	YES
4405488	25897491	GS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405488	25897491	HF	PLoS5	Wrote the paper|Interpreted the results|Reviewed the final manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405488	25897491	HF	PLoS5	Wrote the paper|Interpreted the results|Reviewed the final manuscript	Interpreted the results	Analyzed the data	Formal analysis	YES
4405488	25897491	HF	PLoS5	Wrote the paper|Interpreted the results|Reviewed the final manuscript	Reviewed the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4405488	25897491	MB	PLoS5	Conceived and designed the experiments|Wrote the paper|Interpreted the results|Reviewed the final manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405488	25897491	MB	PLoS5	Conceived and designed the experiments|Wrote the paper|Interpreted the results|Reviewed the final manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405488	25897491	MB	PLoS5	Conceived and designed the experiments|Wrote the paper|Interpreted the results|Reviewed the final manuscript	Interpreted the results	Analyzed the data	Formal analysis	YES
4405488	25897491	MB	PLoS5	Conceived and designed the experiments|Wrote the paper|Interpreted the results|Reviewed the final manuscript	Reviewed the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4405488	25897491	MT	PLoS5	Wrote the paper|Reviewed the final manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405488	25897491	MT	PLoS5	Wrote the paper|Reviewed the final manuscript	Reviewed the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4405488	25897491	TRG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Interpreted the results	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405488	25897491	TRG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Interpreted the results	Analyzed the data	Analyzed the data	Formal analysis	YES
4405488	25897491	TRG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Interpreted the results	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405488	25897491	TRG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Interpreted the results	Interpreted the results	Analyzed the data	Formal analysis	YES
6288959	30537970	AG	2	help maintain the nhs database, gave demographic information, and reviewed the protocol and made edits to the manuscript	help maintain the nhs database, gave demographic information, and reviewed the protocol and made edits to the manuscript	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Methodology|Software|Writing - Review & Editing	YES
6288959	30537970	All authors	2	participated in the design of the study and manuscript preparation|read and approved the final manuscript	participated in the design of the study and manuscript preparation	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
6288959	30537970	All authors	2	participated in the design of the study and manuscript preparation|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6288959	30537970	BKA	2	help maintain the nhs database, gave demographic information, and reviewed the protocol and made edits to the manuscript	help maintain the nhs database, gave demographic information, and reviewed the protocol and made edits to the manuscript	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Methodology|Software|Writing - Review & Editing	YES
6288959	30537970	HSP	2	wrote the concept sheet, collected the data and was the main author the paper	wrote the concept sheet, collected the data and was the main author the paper	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
6288959	30537970	IRB	2	approved and full complete consent was obtained|approved and full complete consent was obtained	approved and full complete consent was obtained	-	-	NO
6288959	30537970	IRB	2	approved and full complete consent was obtained|approved and full complete consent was obtained	approved and full complete consent was obtained	-	-	NO
6288959	30537970	JFO	2	was the primary investigator and helped with study design and edited the manuscript as well	was the primary investigator and helped with study design and edited the manuscript as well	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
6288959	30537970	JW	2	performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
6288959	30537970	RGD	2	help maintain the nhs database, gave demographic information, and reviewed the protocol and made edits to the manuscript	help maintain the nhs database, gave demographic information, and reviewed the protocol and made edits to the manuscript	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Methodology|Software|Writing - Review & Editing	YES
6288959	30537970	TSS	2	help maintain the nhs database, gave demographic information, and reviewed the protocol and made edits to the manuscript	help maintain the nhs database, gave demographic information, and reviewed the protocol and made edits to the manuscript	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Methodology|Software|Writing - Review & Editing	YES
6288959	30537970	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
6288959	30537970	XX	2	performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
5874559	29495553	L.A.	2	were involved in the study concept and design, acquisition, analysis, and interpretation of data	were involved in the study concept and design, acquisition, analysis, and interpretation of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation|Methodology	YES
5874559	29495553	M.G.	2	were involved in the study concept and design, acquisition, analysis, and interpretation of data|performed the statistical analysis|participated in critical revision of the manuscript, contributed comments, and approved the final version	were involved in the study concept and design, acquisition, analysis, and interpretation of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation|Methodology	YES
5874559	29495553	M.G.	2	were involved in the study concept and design, acquisition, analysis, and interpretation of data|performed the statistical analysis|participated in critical revision of the manuscript, contributed comments, and approved the final version	performed the statistical analysis	Analyzed the data	Formal analysis	YES
5874559	29495553	M.G.	2	were involved in the study concept and design, acquisition, analysis, and interpretation of data|performed the statistical analysis|participated in critical revision of the manuscript, contributed comments, and approved the final version	participated in critical revision of the manuscript, contributed comments, and approved the final version	Wrote the paper	Writing - Review & Editing	YES
5377241	28392915	Atsushi Sato	1	Data collections	Data collections	Performed the experiments	Investigation	YES
5377241	28392915	Hiroshi Takagi	1	Study design|Data collections|Analysis|Writing	Study design	Conceived and designed the experiments	Methodology	YES
5377241	28392915	Hiroshi Takagi	1	Study design|Data collections|Analysis|Writing	Data collections	Performed the experiments	Investigation	YES
5377241	28392915	Hiroshi Takagi	1	Study design|Data collections|Analysis|Writing	Analysis	-	-	NO
5377241	28392915	Hiroshi Takagi	1	Study design|Data collections|Analysis|Writing	Writing	Wrote the paper	-	YES
5377241	28392915	Humiyoshi Kawashima	1	Data collections	Data collections	Performed the experiments	Investigation	YES
5377241	28392915	Koji Kanzaki	1	Analysis	Analysis	-	-	NO
5377241	28392915	Masahiko Maekawa	1	Analysis	Analysis	-	-	NO
5377241	28392915	Soshi Asai	1	Data collections	Data collections	Performed the experiments	Investigation	YES
5294800	28166730	CC	PLoS52	developed the algorithms for alternative splicing analysis	developed the algorithms for alternative splicing analysis	Contributed reagents/materials/analysis tools	Software	YES
5294800	28166730	DC	PLoS52	performed most of the statistical analysis and figure production	performed most of the statistical analysis and figure production	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
5294800	28166730	DY	PLoS52	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5294800	28166730	GL	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5294800	28166730	LJ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5294800	28166730	QW	PLoS52	designed and analyzed rt pcr validation experiments	designed and analyzed rt pcr validation experiments	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology|Validation	YES
5294800	28166730	SL	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5294800	28166730	WH	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5294800	28166730	YZ	PLoS52	designed the study|wrote the paper	designed the study	Conceived and designed the experiments	Methodology	YES
5294800	28166730	YZ	PLoS52	designed the study|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5540892	28824686	All authors	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5540892	28824686	G-RY	PLoS52	designed research|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
5540892	28824686	G-RY	PLoS52	designed research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5540892	28824686	JS	PLoS52	designed research	designed research	Conceived and designed the experiments	Methodology	YES
5540892	28824686	JZ	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
5540892	28824686	L-YX	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5540892	28824686	QC	PLoS52	designed research|performed research|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
5540892	28824686	QC	PLoS52	designed research|performed research|wrote the paper	performed research	Performed the experiments	Investigation	YES
5540892	28824686	QC	PLoS52	designed research|performed research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5540892	28824686	W-PD	PLoS52	designed research	designed research	Conceived and designed the experiments	Methodology	YES
5540892	28824686	X-LX	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
5540892	28824686	YJ	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
4813610	28326129	AA	2	prepared the draft|developed the initial study design and protocol	prepared the draft	Wrote the paper	Writing - Original Draft	YES
4813610	28326129	AA	2	prepared the draft|developed the initial study design and protocol	developed the initial study design and protocol	Conceived and designed the experiments	Methodology	YES
4813610	28326129	AAm	2	provided inputs to the first draft	provided inputs to the first draft	Wrote the paper	Writing - Original Draft	YES
4813610	28326129	AAr	2	provided feedback on the outline and substantially strengthened the first draft	provided feedback on the outline and substantially strengthened the first draft	Wrote the paper	Writing - Original Draft	YES
4813610	28326129	AC	2	contributed to the conceptualization and design of the study	contributed to the conceptualization and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4813610	28326129	ACH	2	developed the manuscript structure and wrote the original draft	developed the manuscript structure and wrote the original draft	Wrote the paper	Writing - Original Draft	YES
4813610	28326129	AK	2	contributed to the conceptualization and design of the study|wrote the first draft of the manuscript and all co-authors critically reviewed and revised the manuscript for intellectual content	contributed to the conceptualization and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4813610	28326129	AK	2	contributed to the conceptualization and design of the study|wrote the first draft of the manuscript and all co-authors critically reviewed and revised the manuscript for intellectual content	wrote the first draft of the manuscript and all co-authors critically reviewed and revised the manuscript for intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4813610	28326129	AN	2	conducted the statistical analyses	conducted the statistical analyses	Analyzed the data	Formal analysis	YES
4813610	28326129	AS	2	provided guidance and editorial support to the article	provided guidance and editorial support to the article	Wrote the paper	Supervision|Writing - Review & Editing	YES
4813610	28326129	AW	2	conceived the study|designed the study|collected the data, and all authors interpreted the data|edited the draft|conceived the study|edited the draft	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4813610	28326129	AW	2	conceived the study|designed the study|collected the data, and all authors interpreted the data|edited the draft|conceived the study|edited the draft	designed the study	Conceived and designed the experiments	Methodology	YES
4813610	28326129	AW	2	conceived the study|designed the study|collected the data, and all authors interpreted the data|edited the draft|conceived the study|edited the draft	collected the data, and all authors interpreted the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4813610	28326129	AW	2	conceived the study|designed the study|collected the data, and all authors interpreted the data|edited the draft|conceived the study|edited the draft	edited the draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4813610	28326129	AW	2	conceived the study|designed the study|collected the data, and all authors interpreted the data|edited the draft|conceived the study|edited the draft	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4813610	28326129	AW	2	conceived the study|designed the study|collected the data, and all authors interpreted the data|edited the draft|conceived the study|edited the draft	edited the draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4813610	28326129	AdP	2	contributed to the conceptualization and design of the study	contributed to the conceptualization and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4813610	28326129	All authors	2	have read and approved the final version|have read and approved the final version|have read and approved the final version|have read and approved the final manuscript|drafted sections of the manuscript|read and approved the final manuscript|have read and approved the final version|approved the final version|designed the study, and collected and interpreted the data|approved the final version|responded to the comments of the reviewers|also reviewed and agreed to the contents of the revised final draft	have read and approved the final version	-	-	NO
4813610	28326129	All authors	2	have read and approved the final version|have read and approved the final version|have read and approved the final version|have read and approved the final manuscript|drafted sections of the manuscript|read and approved the final manuscript|have read and approved the final version|approved the final version|designed the study, and collected and interpreted the data|approved the final version|responded to the comments of the reviewers|also reviewed and agreed to the contents of the revised final draft	have read and approved the final version	-	-	NO
4813610	28326129	All authors	2	have read and approved the final version|have read and approved the final version|have read and approved the final version|have read and approved the final manuscript|drafted sections of the manuscript|read and approved the final manuscript|have read and approved the final version|approved the final version|designed the study, and collected and interpreted the data|approved the final version|responded to the comments of the reviewers|also reviewed and agreed to the contents of the revised final draft	have read and approved the final version	-	-	NO
4813610	28326129	All authors	2	have read and approved the final version|have read and approved the final version|have read and approved the final version|have read and approved the final manuscript|drafted sections of the manuscript|read and approved the final manuscript|have read and approved the final version|approved the final version|designed the study, and collected and interpreted the data|approved the final version|responded to the comments of the reviewers|also reviewed and agreed to the contents of the revised final draft	have read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4813610	28326129	All authors	2	have read and approved the final version|have read and approved the final version|have read and approved the final version|have read and approved the final manuscript|drafted sections of the manuscript|read and approved the final manuscript|have read and approved the final version|approved the final version|designed the study, and collected and interpreted the data|approved the final version|responded to the comments of the reviewers|also reviewed and agreed to the contents of the revised final draft	drafted sections of the manuscript	Wrote the paper	Writing - Original Draft	YES
4813610	28326129	All authors	2	have read and approved the final version|have read and approved the final version|have read and approved the final version|have read and approved the final manuscript|drafted sections of the manuscript|read and approved the final manuscript|have read and approved the final version|approved the final version|designed the study, and collected and interpreted the data|approved the final version|responded to the comments of the reviewers|also reviewed and agreed to the contents of the revised final draft	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4813610	28326129	All authors	2	have read and approved the final version|have read and approved the final version|have read and approved the final version|have read and approved the final manuscript|drafted sections of the manuscript|read and approved the final manuscript|have read and approved the final version|approved the final version|designed the study, and collected and interpreted the data|approved the final version|responded to the comments of the reviewers|also reviewed and agreed to the contents of the revised final draft	have read and approved the final version	-	-	NO
4813610	28326129	All authors	2	have read and approved the final version|have read and approved the final version|have read and approved the final version|have read and approved the final manuscript|drafted sections of the manuscript|read and approved the final manuscript|have read and approved the final version|approved the final version|designed the study, and collected and interpreted the data|approved the final version|responded to the comments of the reviewers|also reviewed and agreed to the contents of the revised final draft	approved the final version	-	-	NO
4813610	28326129	All authors	2	have read and approved the final version|have read and approved the final version|have read and approved the final version|have read and approved the final manuscript|drafted sections of the manuscript|read and approved the final manuscript|have read and approved the final version|approved the final version|designed the study, and collected and interpreted the data|approved the final version|responded to the comments of the reviewers|also reviewed and agreed to the contents of the revised final draft	designed the study, and collected and interpreted the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
4813610	28326129	All authors	2	have read and approved the final version|have read and approved the final version|have read and approved the final version|have read and approved the final manuscript|drafted sections of the manuscript|read and approved the final manuscript|have read and approved the final version|approved the final version|designed the study, and collected and interpreted the data|approved the final version|responded to the comments of the reviewers|also reviewed and agreed to the contents of the revised final draft	approved the final version	-	-	NO
4813610	28326129	All authors	2	have read and approved the final version|have read and approved the final version|have read and approved the final version|have read and approved the final manuscript|drafted sections of the manuscript|read and approved the final manuscript|have read and approved the final version|approved the final version|designed the study, and collected and interpreted the data|approved the final version|responded to the comments of the reviewers|also reviewed and agreed to the contents of the revised final draft	responded to the comments of the reviewers	-	-	NO
4813610	28326129	All authors	2	have read and approved the final version|have read and approved the final version|have read and approved the final version|have read and approved the final manuscript|drafted sections of the manuscript|read and approved the final manuscript|have read and approved the final version|approved the final version|designed the study, and collected and interpreted the data|approved the final version|responded to the comments of the reviewers|also reviewed and agreed to the contents of the revised final draft	also reviewed and agreed to the contents of the revised final draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4813610	28326129	CC	2	edited the draft	edited the draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4813610	28326129	CK	2	developed the initial study design and protocol|conducted the search, screening and data abstraction	developed the initial study design and protocol	Conceived and designed the experiments	Methodology	YES
4813610	28326129	CK	2	developed the initial study design and protocol|conducted the search, screening and data abstraction	conducted the search, screening and data abstraction	Performed the experiments	Investigation	YES
4813610	28326129	CL	2	edited the draft	edited the draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4813610	28326129	CRC	2	assisted with the background and editing of the paper	assisted with the background and editing of the paper	Wrote the paper	Writing - Review & Editing	YES
4813610	28326129	ES	2	provided guidance and editorial support to the article	provided guidance and editorial support to the article	Wrote the paper	Supervision|Writing - Review & Editing	YES
4813610	28326129	ETC	2	conceived the study|designed the study|collected the data, and all authors interpreted the data|conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4813610	28326129	ETC	2	conceived the study|designed the study|collected the data, and all authors interpreted the data|conceived the study	designed the study	Conceived and designed the experiments	Methodology	YES
4813610	28326129	ETC	2	conceived the study|designed the study|collected the data, and all authors interpreted the data|conceived the study	collected the data, and all authors interpreted the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4813610	28326129	ETC	2	conceived the study|designed the study|collected the data, and all authors interpreted the data|conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4813610	28326129	GC	2	conducted the statistical analyses	conducted the statistical analyses	Analyzed the data	Formal analysis	YES
4813610	28326129	H. All	2	authors collaboratively discussed key decisions through the course of the review, provided critical feedback on preliminary drafts and interpretation of results and approved the final manuscript	authors collaboratively discussed key decisions through the course of the review, provided critical feedback on preliminary drafts and interpretation of results and approved the final manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
4813610	28326129	HN	2	edited the draft	edited the draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4813610	28326129	JF	2	contributed to the development of the outline of the paper and provided inputs to the first draft	contributed to the development of the outline of the paper and provided inputs to the first draft	Wrote the paper	Writing - Original Draft	YES
4813610	28326129	JTP	2	contributed to the conceptualization and design of the study	contributed to the conceptualization and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4813610	28326129	KB	2	contributed to the conceptualization and design of the study	contributed to the conceptualization and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4813610	28326129	KPB	2	contributed to the conceptualization and design of the study	contributed to the conceptualization and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4813610	28326129	LO	2	conceived the study|designed the study|collected the data, and all authors interpreted the data|edited the draft|conceived the study|edited the draft	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4813610	28326129	LO	2	conceived the study|designed the study|collected the data, and all authors interpreted the data|edited the draft|conceived the study|edited the draft	designed the study	Conceived and designed the experiments	Methodology	YES
4813610	28326129	LO	2	conceived the study|designed the study|collected the data, and all authors interpreted the data|edited the draft|conceived the study|edited the draft	collected the data, and all authors interpreted the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4813610	28326129	LO	2	conceived the study|designed the study|collected the data, and all authors interpreted the data|edited the draft|conceived the study|edited the draft	edited the draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4813610	28326129	LO	2	conceived the study|designed the study|collected the data, and all authors interpreted the data|edited the draft|conceived the study|edited the draft	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4813610	28326129	LO	2	conceived the study|designed the study|collected the data, and all authors interpreted the data|edited the draft|conceived the study|edited the draft	edited the draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4813610	28326129	MH	2	provided guidance and editorial support to the article	provided guidance and editorial support to the article	Wrote the paper	Supervision|Writing - Review & Editing	YES
4813610	28326129	MJH	2	conceptualized the paper and wrote the manuscript	conceptualized the paper and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4813610	28326129	MJV	2	conceived the study|designed the study|collected the data, and all authors interpreted the data|conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4813610	28326129	MJV	2	conceived the study|designed the study|collected the data, and all authors interpreted the data|conceived the study	designed the study	Conceived and designed the experiments	Methodology	YES
4813610	28326129	MJV	2	conceived the study|designed the study|collected the data, and all authors interpreted the data|conceived the study	collected the data, and all authors interpreted the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4813610	28326129	MJV	2	conceived the study|designed the study|collected the data, and all authors interpreted the data|conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4813610	28326129	ML	2	contributed to the conceptualization and design of the study	contributed to the conceptualization and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4813610	28326129	MM	2	contributed data and ideas for the structure of the paper	contributed data and ideas for the structure of the paper	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceptualization|Resources	YES
4813610	28326129	MN	2	provided intellectual guidance and content at every step of the study and manuscript revisions|contributed data and ideas for the structure of the paper|developed the initial study design and protocol	provided intellectual guidance and content at every step of the study and manuscript revisions	Wrote the paper	Supervision|Writing - Review & Editing	YES
4813610	28326129	MN	2	provided intellectual guidance and content at every step of the study and manuscript revisions|contributed data and ideas for the structure of the paper|developed the initial study design and protocol	contributed data and ideas for the structure of the paper	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceptualization|Resources	YES
4813610	28326129	MN	2	provided intellectual guidance and content at every step of the study and manuscript revisions|contributed data and ideas for the structure of the paper|developed the initial study design and protocol	developed the initial study design and protocol	Conceived and designed the experiments	Methodology	YES
4813610	28326129	MT	2	reviewed the manuscript and provided comments|worked on finalization of the manuscript	reviewed the manuscript and provided comments	Wrote the paper	Writing - Review & Editing	YES
4813610	28326129	MT	2	reviewed the manuscript and provided comments|worked on finalization of the manuscript	worked on finalization of the manuscript	Performed the experiments|Wrote the paper	Writing - Review & Editing	YES
4813610	28326129	NO	2	contributed to the conceptualization and design of the study	contributed to the conceptualization and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4813610	28326129	NVB	2	co-drafted the manuscript|worked on finalization of the manuscript	co-drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4813610	28326129	NVB	2	co-drafted the manuscript|worked on finalization of the manuscript	worked on finalization of the manuscript	Performed the experiments|Wrote the paper	Writing - Review & Editing	YES
4813610	28326129	PS	2	conducted the statistical analyses	conducted the statistical analyses	Analyzed the data	Formal analysis	YES
4813610	28326129	RB	2	developed the initial study design and protocol	developed the initial study design and protocol	Conceived and designed the experiments	Methodology	YES
4813610	28326129	RH	2	revised and edited the manuscript and all authors critically reviewed and provided recommended editing and alterations to the manuscript	revised and edited the manuscript and all authors critically reviewed and provided recommended editing and alterations to the manuscript	Wrote the paper	Writing - Review & Editing	YES
4813610	28326129	RK	2	co-drafted the manuscript|worked on finalization of the manuscript|provided intellectual guidance and content at every step of the study and manuscript revisions	co-drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4813610	28326129	RK	2	co-drafted the manuscript|worked on finalization of the manuscript|provided intellectual guidance and content at every step of the study and manuscript revisions	worked on finalization of the manuscript	Performed the experiments|Wrote the paper	Writing - Review & Editing	YES
4813610	28326129	RK	2	co-drafted the manuscript|worked on finalization of the manuscript|provided intellectual guidance and content at every step of the study and manuscript revisions	provided intellectual guidance and content at every step of the study and manuscript revisions	Wrote the paper	Supervision|Writing - Review & Editing	YES
4813610	28326129	RM	2	developed the manuscript structure and wrote the original draft	developed the manuscript structure and wrote the original draft	Wrote the paper	Writing - Original Draft	YES
4813610	28326129	RSH	2	contributed to the conceptualization and design of the study	contributed to the conceptualization and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4813610	28326129	SB	2	provided guidance and editorial support to the article|conceived the study|designed the study|collected the data, and all authors interpreted the data|edited the draft|conceived the study|edited the draft	provided guidance and editorial support to the article	Wrote the paper	Supervision|Writing - Review & Editing	YES
4813610	28326129	SB	2	provided guidance and editorial support to the article|conceived the study|designed the study|collected the data, and all authors interpreted the data|edited the draft|conceived the study|edited the draft	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4813610	28326129	SB	2	provided guidance and editorial support to the article|conceived the study|designed the study|collected the data, and all authors interpreted the data|edited the draft|conceived the study|edited the draft	designed the study	Conceived and designed the experiments	Methodology	YES
4813610	28326129	SB	2	provided guidance and editorial support to the article|conceived the study|designed the study|collected the data, and all authors interpreted the data|edited the draft|conceived the study|edited the draft	collected the data, and all authors interpreted the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4813610	28326129	SB	2	provided guidance and editorial support to the article|conceived the study|designed the study|collected the data, and all authors interpreted the data|edited the draft|conceived the study|edited the draft	edited the draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4813610	28326129	SB	2	provided guidance and editorial support to the article|conceived the study|designed the study|collected the data, and all authors interpreted the data|edited the draft|conceived the study|edited the draft	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4813610	28326129	SB	2	provided guidance and editorial support to the article|conceived the study|designed the study|collected the data, and all authors interpreted the data|edited the draft|conceived the study|edited the draft	edited the draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4813610	28326129	SD	2	provided guidance and editorial support to the article	provided guidance and editorial support to the article	Wrote the paper	Supervision|Writing - Review & Editing	YES
4813610	28326129	SG	2	conceptualized and designed the study and provided intellectual guidance and content at every step of the study and manuscript revisions	conceptualized and designed the study and provided intellectual guidance and content at every step of the study and manuscript revisions	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Supervision|Writing - Review & Editing	YES
4813610	28326129	SH	2	conducted the search, screening and data abstraction	conducted the search, screening and data abstraction	Performed the experiments	Investigation	YES
4813610	28326129	SK	2	led data collection, analysis and manuscript writing	led data collection, analysis and manuscript writing	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4813610	28326129	SM	2	designed the study|collected the data, and all authors interpreted the data|edited the draft	designed the study	Conceived and designed the experiments	Methodology	YES
4813610	28326129	SM	2	designed the study|collected the data, and all authors interpreted the data|edited the draft	collected the data, and all authors interpreted the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4813610	28326129	SM	2	designed the study|collected the data, and all authors interpreted the data|edited the draft	edited the draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4813610	28326129	SMB	2	developed the manuscript structure and wrote the original draft	developed the manuscript structure and wrote the original draft	Wrote the paper	Writing - Original Draft	YES
4813610	28326129	SP	2	contributed to the conceptualization and design of the study	contributed to the conceptualization and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4813610	28326129	SS	2	designed the study|collected the data, and all authors interpreted the data|edited the draft	designed the study	Conceived and designed the experiments	Methodology	YES
4813610	28326129	SS	2	designed the study|collected the data, and all authors interpreted the data|edited the draft	collected the data, and all authors interpreted the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4813610	28326129	SS	2	designed the study|collected the data, and all authors interpreted the data|edited the draft	edited the draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4813610	28326129	VC	2	conceived the paper, developed the outline and prepared the first draft	conceived the paper, developed the outline and prepared the first draft	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4813610	28326129	VJN	2	contributed to the conceptualization and design of the study	contributed to the conceptualization and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4813610	28326129	WT	2	contributed to the conceptualization and design of the study	contributed to the conceptualization and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405492	25897494	EKH	PLoS5	Further adivisory adds for experiments	Further adivisory adds for experiments	-	-	NO
4405492	25897494	HKS	PLoS5	Contributed reagents/materials/analysis tools|Further adivisory adds for experiments	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405492	25897494	HKS	PLoS5	Contributed reagents/materials/analysis tools|Further adivisory adds for experiments	Further adivisory adds for experiments	-	-	NO
4405492	25897494	JC	PLoS5	Contributed reagents/materials/analysis tools|Further adivisory adds for experiments	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405492	25897494	JC	PLoS5	Contributed reagents/materials/analysis tools|Further adivisory adds for experiments	Further adivisory adds for experiments	-	-	NO
4405492	25897494	JYJ	PLoS5	Further adivisory adds for experiments	Further adivisory adds for experiments	-	-	NO
4405492	25897494	KHL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405492	25897494	KHL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405492	25897494	WSP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405492	25897494	WSP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
6291979	30541577	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6291979	30541577	CG	2	provided critical revision of the manuscript	provided critical revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
6291979	30541577	MB	2	wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
6291979	30541577	MG	2	wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
5874560	29495567	A.S.	PLoS52	wrote the paper|reviewed the protocols and the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5874560	29495567	A.S.	PLoS52	wrote the paper|reviewed the protocols and the paper	reviewed the protocols and the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5874560	29495567	E.T.	PLoS52	conceived and designed the study, analyzed the data, and wrote the paper	conceived and designed the study, analyzed the data, and wrote the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
5874560	29495567	K.B.	PLoS52	reviewed the protocols and the paper	reviewed the protocols and the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5874560	29495567	L.D.B.	PLoS52	conceived and designed the study, analyzed the data, and wrote the paper	conceived and designed the study, analyzed the data, and wrote the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
5874560	29495567	W.M.	PLoS52	reviewed the protocols and the paper	reviewed the protocols and the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
4405493	25898021	DI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405493	25898021	DI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4405493	25898021	DI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4405493	25898021	DI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405493	25898021	DT	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405493	25898021	DT	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4405493	25898021	DT	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405493	25898021	PN	PLoS5	Conceived and designed the experiments|Reviewed and revised the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405493	25898021	PN	PLoS5	Conceived and designed the experiments|Reviewed and revised the manuscript	Reviewed and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4405493	25898021	RH	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4405493	25898021	SFN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405493	25898021	SFN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405493	25898021	SFN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405493	25898021	SFN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405493	25898021	SFN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5379933	28408986	Atsuko Tsutsui	7	performed procedures	performed procedures	Performed the experiments	Investigation	YES
5379933	28408986	Hirohisa Miura	7	performed procedures	performed procedures	Performed the experiments	Investigation	YES
5379933	28408986	Masahiko Watanabe	7	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5379933	28408986	Masanori Naito	7	designed the study, performed procedures, collected data, composed the manuscript	designed the study, performed procedures, collected data, composed the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5379933	28408986	Takahiro Yamanashi	7	performed procedures	performed procedures	Performed the experiments	Investigation	YES
5379933	28408986	Takatoshi Nakamura	7	performed procedures	performed procedures	Performed the experiments	Investigation	YES
5379933	28408986	Takeo Sato	7	performed procedures	performed procedures	Performed the experiments	Investigation	YES
5294808	28166737	KM	2	provided critical input to the study design and bioinformatics analyses	provided critical input to the study design and bioinformatics analyses	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5294808	28166737	MB	2	participated in the study design, carried out greenhouse and laboratory work, performed bioinformatics analyses and drafted the manuscript	participated in the study design, carried out greenhouse and laboratory work, performed bioinformatics analyses and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5294808	28166737	MK	2	conceived and supervised the study and revised the manuscript	conceived and supervised the study and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Supervision|Writing - Review & Editing	YES
5294808	28166737	PK	2	supervised and revised the manuscript	supervised and revised the manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
5294808	28166737	SKM	2	provided critical input to the study design and supervised the study	provided critical input to the study design and supervised the study	Conceived and designed the experiments	Methodology|Supervision	YES
5540898	28824684	AM-R	5	acquired all data and contributed to the design of the work	acquired all data and contributed to the design of the work	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5540898	28824684	BK	5	conceived the work	conceived the work	Conceived and designed the experiments	Conceptualization	YES
6300903	30572924	AM	CRediT2	writing--original draft preparation	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6300903	30572924	All authors	CRediT2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6300903	30572924	CV	CRediT2	writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6300903	30572924	GRa	CRediT2	writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6300903	30572924	GRo	CRediT2	writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6300903	30572924	MCR	CRediT2	writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6300903	30572924	PG	CRediT2	writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6300903	30572924	SV	CRediT2	writing--original draft preparation	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6300903	30572924	VS	CRediT2	writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
5540907	28824693	AK	7	Section Selenoglucosiolates for Human nutrition	Section Selenoglucosiolates for Human nutrition	-	-	NO
5540907	28824693	DR	7	Section Instrumental Approaches for Detecting, Measuring, and Monitoring Selenium and Its Metabolites within Brassica Species	Section Instrumental Approaches for Detecting, Measuring, and Monitoring Selenium and Its Metabolites within Brassica Species	-	Supervision	YES
5540907	28824693	DS	7	Section Selenium in Brassicales	Section Selenium in Brassicales	-	-	NO
5540907	28824693	FSH	7	Section Selenium in Brassicales|Section Selenoglucosiolates for Human nutrition	Section Selenium in Brassicales	-	-	NO
5540907	28824693	FSH	7	Section Selenium in Brassicales|Section Selenoglucosiolates for Human nutrition	Section Selenoglucosiolates for Human nutrition	-	-	NO
5540907	28824693	KBH	7	Section Selenoglucosiolates for Human nutrition	Section Selenoglucosiolates for Human nutrition	-	-	NO
5540907	28824693	MM	7	Section Selenium in Brassicales	Section Selenium in Brassicales	-	-	NO
5540907	28824693	MS	7	Section Selenium in Brassicales	Section Selenium in Brassicales	-	-	NO
5540907	28824693	MW	7	Corresponding author|Section Selenoglucosiolates for Human nutrition	Corresponding author	-	-	NO
5540907	28824693	MW	7	Corresponding author|Section Selenoglucosiolates for Human nutrition	Section Selenoglucosiolates for Human nutrition	-	-	NO
5540907	28824693	SB	7	Section Instrumental Approaches for Detecting, Measuring, and Monitoring Selenium and Its Metabolites within Brassica Species	Section Instrumental Approaches for Detecting, Measuring, and Monitoring Selenium and Its Metabolites within Brassica Species	-	Supervision	YES
5874561	29510544	A.C.	PLoS52	conceived and designed the survey|analyzed the data|wrote the paper	conceived and designed the survey	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5874561	29510544	A.C.	PLoS52	conceived and designed the survey|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5874561	29510544	A.C.	PLoS52	conceived and designed the survey|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5874561	29510544	L.K.	PLoS52	performed the data collection|analyzed the data|wrote the paper	performed the data collection	Performed the experiments	Investigation	YES
5874561	29510544	L.K.	PLoS52	performed the data collection|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5874561	29510544	L.K.	PLoS52	performed the data collection|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5874561	29510544	S.X.	PLoS52	performed the data collection|analyzed the data	performed the data collection	Performed the experiments	Investigation	YES
5874561	29510544	S.X.	PLoS52	performed the data collection|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
4405499	25898130	GSZ	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405499	25898130	GSZ	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405499	25898130	JWW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405499	25898130	JZ	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4405499	25898130	JZ	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405499	25898130	LJ	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4405499	25898130	LJ	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405499	25898130	NN	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405499	25898130	QDZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405499	25898130	QDZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405499	25898130	QDZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405499	25898130	QDZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405499	25898130	QDZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405499	25898130	SCM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405499	25898130	YAY	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4405499	25898130	YAY	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405499	25898130	YLS	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405499	25898130	YLS	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5382030	28408988	Atsuko Tsutsui	7	performed procedures	performed procedures	Performed the experiments	Investigation	YES
5382030	28408988	Hirohisa Miura	7	performed procedures	performed procedures	Performed the experiments	Investigation	YES
5382030	28408988	Masahiko Watanabe	7	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5382030	28408988	Masanori Naito	7	designed the study, performed procedures, collected data, composed the manuscript	designed the study, performed procedures, collected data, composed the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5382030	28408988	Takahiro Yamanashi	7	performed procedures	performed procedures	Performed the experiments	Investigation	YES
5382030	28408988	Takatoshi Nakamura	7	performed procedures	performed procedures	Performed the experiments	Investigation	YES
5382030	28408988	Takeo Sato	7	performed procedures	performed procedures	Performed the experiments	Investigation	YES
6302453	30577866	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6302453	30577866	CK	2	wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
6302453	30577866	DR	2	reviewed the literature and provided critical revision of the manuscript	reviewed the literature and provided critical revision of the manuscript	Wrote the paper	Formal analysis|Writing - Review & Editing	YES
6302453	30577866	GM	2	reviewed the literature and provided critical revision of the manuscript	reviewed the literature and provided critical revision of the manuscript	Wrote the paper	Formal analysis|Writing - Review & Editing	YES
6302453	30577866	TR	2	reviewed the literature and provided critical revision of the manuscript	reviewed the literature and provided critical revision of the manuscript	Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4813611	28326130	AA	2	revised the draft, assisted in literature search and ensured consistency and accuracy of the manuscript contents	revised the draft, assisted in literature search and ensured consistency and accuracy of the manuscript contents	Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
4813611	28326130	AN	2	contributed to the manuscript and approved the final version	contributed to the manuscript and approved the final version	-	-	NO
4813611	28326130	AO	2	contributed to further drafts	contributed to further drafts	Wrote the paper	Writing - Original Draft	YES
4813611	28326130	All authors	2	approved the final manuscript|contributed to literature review and writing the manuscript|have read and approved the manuscript|have read and approved the final version|have read and approved the final version|contributed to writing and review, and all read and approved the final version	approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4813611	28326130	All authors	2	approved the final manuscript|contributed to literature review and writing the manuscript|have read and approved the manuscript|have read and approved the final version|have read and approved the final version|contributed to writing and review, and all read and approved the final version	contributed to literature review and writing the manuscript	Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
4813611	28326130	All authors	2	approved the final manuscript|contributed to literature review and writing the manuscript|have read and approved the manuscript|have read and approved the final version|have read and approved the final version|contributed to writing and review, and all read and approved the final version	have read and approved the manuscript	-	-	NO
4813611	28326130	All authors	2	approved the final manuscript|contributed to literature review and writing the manuscript|have read and approved the manuscript|have read and approved the final version|have read and approved the final version|contributed to writing and review, and all read and approved the final version	have read and approved the final version	-	-	NO
4813611	28326130	All authors	2	approved the final manuscript|contributed to literature review and writing the manuscript|have read and approved the manuscript|have read and approved the final version|have read and approved the final version|contributed to writing and review, and all read and approved the final version	have read and approved the final version	-	-	NO
4813611	28326130	All authors	2	approved the final manuscript|contributed to literature review and writing the manuscript|have read and approved the manuscript|have read and approved the final version|have read and approved the final version|contributed to writing and review, and all read and approved the final version	contributed to writing and review, and all read and approved the final version	Wrote the paper	Writing - Review & Editing	YES
4813611	28326130	All co-authors	2	contributed equally to the conceptualization and design of this article	contributed equally to the conceptualization and design of this article	Conceived and designed the experiments	Conceptualization	YES
4813611	28326130	CL	2	revised the draft, assisted in literature search and ensured consistency and accuracy of the manuscript contents	revised the draft, assisted in literature search and ensured consistency and accuracy of the manuscript contents	Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
4813611	28326130	CW	2	contributed to the manuscript and approved the final version	contributed to the manuscript and approved the final version	-	-	NO
4813611	28326130	DC	2	generated the first draft of the manuscript, coordinated inputs and comments and revised and submitted the article for peer review	generated the first draft of the manuscript, coordinated inputs and comments and revised and submitted the article for peer review	Performed the experiments|Wrote the paper	Investigation|Project administration|Writing - Original Draft|Writing - Review & Editing	YES
4813611	28326130	EC	2	contributed to further drafts	contributed to further drafts	Wrote the paper	Writing - Original Draft	YES
4813611	28326130	EJA	2	each contributed to the content, writing and editing of this manuscript	each contributed to the content, writing and editing of this manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4813611	28326130	FP	2	contributed to further drafts	contributed to further drafts	Wrote the paper	Writing - Original Draft	YES
4813611	28326130	HR	2	contributed to the manuscript and approved the final version	contributed to the manuscript and approved the final version	-	-	NO
4813611	28326130	JL	2	wrote the first draft	wrote the first draft	Wrote the paper	Writing - Original Draft	YES
4813611	28326130	KCES	2	conceived the manuscript and wrote the first draft	conceived the manuscript and wrote the first draft	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4813611	28326130	LC	2	conceptualized the paper	conceptualized the paper	Conceived and designed the experiments	Conceptualization	YES
4813611	28326130	MBH	2	participated in the discussion of results and critically reviewed the final paper	participated in the discussion of results and critically reviewed the final paper	Wrote the paper	Writing - Review & Editing	YES
4813611	28326130	MFC	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4813611	28326130	ML	2	wrote the first draft	wrote the first draft	Wrote the paper	Writing - Original Draft	YES
4813611	28326130	MLS	2	contributed significantly to the literature review and writing of the manuscript	contributed significantly to the literature review and writing of the manuscript	Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
4813611	28326130	MM	2	contributed to the manuscript and approved the final version	contributed to the manuscript and approved the final version	-	-	NO
4813611	28326130	MP	2	wrote the first draft	wrote the first draft	Wrote the paper	Writing - Original Draft	YES
4813611	28326130	MSM	2	contributed significantly to the literature review and writing of the manuscript	contributed significantly to the literature review and writing of the manuscript	Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
4813611	28326130	MY	2	revised the draft, assisted in literature search and ensured consistency and accuracy of the manuscript contents	revised the draft, assisted in literature search and ensured consistency and accuracy of the manuscript contents	Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
4813611	28326130	NF	2	contributed to further drafts	contributed to further drafts	Wrote the paper	Writing - Original Draft	YES
4813611	28326130	NS	2	contributed to further drafts|revised the draft, assisted in literature search and ensured consistency and accuracy of the manuscript contents	contributed to further drafts	Wrote the paper	Writing - Original Draft	YES
4813611	28326130	NS	2	contributed to further drafts|revised the draft, assisted in literature search and ensured consistency and accuracy of the manuscript contents	revised the draft, assisted in literature search and ensured consistency and accuracy of the manuscript contents	Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
4813611	28326130	RCV	2	led the design and writing of the manuscript	led the design and writing of the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
4813611	28326130	RH	2	designed, reviewed and revised the manuscript|conceptualized the paper	designed, reviewed and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Review & Editing	YES
4813611	28326130	RH	2	designed, reviewed and revised the manuscript|conceptualized the paper	conceptualized the paper	Conceived and designed the experiments	Conceptualization	YES
4813611	28326130	RL	2	revised the draft, assisted in literature search and ensured consistency and accuracy of the manuscript contents	revised the draft, assisted in literature search and ensured consistency and accuracy of the manuscript contents	Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
4813611	28326130	RSB	2	performed the literature review and finalized the manuscript	performed the literature review and finalized the manuscript	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
4813611	28326130	SE	2	contributed to further drafts|revised the draft, assisted in literature search and ensured consistency and accuracy of the manuscript contents	contributed to further drafts	Wrote the paper	Writing - Original Draft	YES
4813611	28326130	SE	2	contributed to further drafts|revised the draft, assisted in literature search and ensured consistency and accuracy of the manuscript contents	revised the draft, assisted in literature search and ensured consistency and accuracy of the manuscript contents	Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
4813611	28326130	SK	2	revised the draft, assisted in literature search and ensured consistency and accuracy of the manuscript contents	revised the draft, assisted in literature search and ensured consistency and accuracy of the manuscript contents	Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
4813611	28326130	SL	2	designed and wrote the manuscript	designed and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
4813611	28326130	SLH	2	contributed to the manuscript and approved the final version	contributed to the manuscript and approved the final version	-	-	NO
4813611	28326130	SS	2	each contributed to the content, writing and editing of this manuscript	each contributed to the content, writing and editing of this manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4813611	28326130	TFRW	2	participated in the discussion of results and critically reviewed the final paper	participated in the discussion of results and critically reviewed the final paper	Wrote the paper	Writing - Review & Editing	YES
4813611	28326130	TSB	2	participated in the discussion of results and critically reviewed the final paper	participated in the discussion of results and critically reviewed the final paper	Wrote the paper	Writing - Review & Editing	YES
4813611	28326130	W. This	2	article was written by all authors and they read and approved the final version	article was written by all authors and they read and approved the final version	Wrote the paper	Writing - Original Draft	YES
4813611	28326130	WMN	2	contributed significantly to the design and revision of the manuscript	contributed significantly to the design and revision of the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Review & Editing	YES
5541011	28824688	AM	2	conducted the experiments and analyzed data	conducted the experiments and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5541011	28824688	AS	2	supervised the hormone analysis	supervised the hormone analysis	-	Supervision	YES
5541011	28824688	FJ	2	supervised the hormone analysis	supervised the hormone analysis	-	Supervision	YES
5541011	28824688	JY	2	designed the experiments and evaluated the data|wrote the article	designed the experiments and evaluated the data	Conceived and designed the experiments	Methodology	YES
5541011	28824688	JY	2	designed the experiments and evaluated the data|wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
5541011	28824688	MH	2	supervised the metabolite analysis|wrote the article	supervised the metabolite analysis	-	Supervision	YES
5541011	28824688	MH	2	supervised the metabolite analysis|wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
5541011	28824688	NA	2	performed gene expression analysis|wrote the article	performed gene expression analysis	Performed the experiments	Investigation	YES
5541011	28824688	NA	2	performed gene expression analysis|wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
5541011	28824688	SH	2	designed the experiments and evaluated the data|wrote the article	designed the experiments and evaluated the data	Conceived and designed the experiments	Methodology	YES
5541011	28824688	SH	2	designed the experiments and evaluated the data|wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
5294817	28166722	AV	2	all participated in the in silico analyses of vdr chip-seq and the gwas catalog	all participated in the in silico analyses of vdr chip-seq and the gwas catalog	Analyzed the data	Formal analysis	YES
5294817	28166722	CC	2	participated in study design and implementation|conceived of the study, and participated in its design and coordination and directed the drafting the manuscript	participated in study design and implementation	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5294817	28166722	CC	2	participated in study design and implementation|conceived of the study, and participated in its design and coordination and directed the drafting the manuscript	conceived of the study, and participated in its design and coordination and directed the drafting the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Supervision|Writing - Original Draft	YES
5294817	28166722	HMO-B	2	participated in study design and implementation	participated in study design and implementation	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5294817	28166722	JW	2	all participated in the in silico analyses of vdr chip-seq and the gwas catalog	all participated in the in silico analyses of vdr chip-seq and the gwas catalog	Analyzed the data	Formal analysis	YES
5294817	28166722	LES-C	2	participated in study design and implementation|conceived of the study, and participated in its design and coordination and directed the drafting the manuscript|prepared the final manuscript and all authors read and approved the final manuscript	participated in study design and implementation	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5294817	28166722	LES-C	2	participated in study design and implementation|conceived of the study, and participated in its design and coordination and directed the drafting the manuscript|prepared the final manuscript and all authors read and approved the final manuscript	conceived of the study, and participated in its design and coordination and directed the drafting the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Supervision|Writing - Original Draft	YES
5294817	28166722	LES-C	2	participated in study design and implementation|conceived of the study, and participated in its design and coordination and directed the drafting the manuscript|prepared the final manuscript and all authors read and approved the final manuscript	prepared the final manuscript and all authors read and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5294817	28166722	LG	2	all participated in the in silico analyses of vdr chip-seq and the gwas catalog	all participated in the in silico analyses of vdr chip-seq and the gwas catalog	Analyzed the data	Formal analysis	YES
5294817	28166722	MDL	2	all participated in the in silico analyses of vdr chip-seq and the gwas catalog	all participated in the in silico analyses of vdr chip-seq and the gwas catalog	Analyzed the data	Formal analysis	YES
5294817	28166722	MJC	2	participated in study design and implementation|conceived of the study, and participated in its design and coordination and directed the drafting the manuscript|prepared the final manuscript and all authors read and approved the final manuscript	participated in study design and implementation	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5294817	28166722	MJC	2	participated in study design and implementation|conceived of the study, and participated in its design and coordination and directed the drafting the manuscript|prepared the final manuscript and all authors read and approved the final manuscript	conceived of the study, and participated in its design and coordination and directed the drafting the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Supervision|Writing - Original Draft	YES
5294817	28166722	MJC	2	participated in study design and implementation|conceived of the study, and participated in its design and coordination and directed the drafting the manuscript|prepared the final manuscript and all authors read and approved the final manuscript	prepared the final manuscript and all authors read and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5294817	28166722	PKS	2	all participated in the in silico analyses of vdr chip-seq and the gwas catalog|participated in study design and implementation|prepared the final manuscript and all authors read and approved the final manuscript	all participated in the in silico analyses of vdr chip-seq and the gwas catalog	Analyzed the data	Formal analysis	YES
5294817	28166722	PKS	2	all participated in the in silico analyses of vdr chip-seq and the gwas catalog|participated in study design and implementation|prepared the final manuscript and all authors read and approved the final manuscript	participated in study design and implementation	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5294817	28166722	PKS	2	all participated in the in silico analyses of vdr chip-seq and the gwas catalog|participated in study design and implementation|prepared the final manuscript and all authors read and approved the final manuscript	prepared the final manuscript and all authors read and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5294817	28166722	PRvdB	2	all participated in the in silico analyses of vdr chip-seq and the gwas catalog	all participated in the in silico analyses of vdr chip-seq and the gwas catalog	Analyzed the data	Formal analysis	YES
5294817	28166722	SD	2	all participated in the in silico analyses of vdr chip-seq and the gwas catalog	all participated in the in silico analyses of vdr chip-seq and the gwas catalog	Analyzed the data	Formal analysis	YES
3588192	23476154	A. Spira	2	contributed equally as cosenior authors	contributed equally as cosenior authors	-	-	NO
3588192	23476154	M. E. Lenburg	2	contributed equally as cosenior authors	contributed equally as cosenior authors	-	-	NO
5385388	28413632	AP	2	conceived the study, and acted as senior authors, editing and providing feedback on the manuscript	conceived the study, and acted as senior authors, editing and providing feedback on the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5385388	28413632	All authors	2	approved the submitted version of the manuscript	approved the submitted version of the manuscript	-	-	NO
5385388	28413632	EMG	2	are medical students who contributed to the esmsc set-up and helped in the data analysis and presentation	are medical students who contributed to the esmsc set-up and helped in the data analysis and presentation	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5385388	28413632	GKZ	2	conceived the study, and acted as senior authors, editing and providing feedback on the manuscript	conceived the study, and acted as senior authors, editing and providing feedback on the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5385388	28413632	GS	2	contributed to the conduction of the experiments as they hold expertise in animal model research	contributed to the conduction of the experiments as they hold expertise in animal model research	Performed the experiments	Investigation|Methodology	YES
5385388	28413632	GT	2	conceived the study, and acted as senior authors, editing and providing feedback on the manuscript	conceived the study, and acted as senior authors, editing and providing feedback on the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5385388	28413632	IT	2	are medical students who contributed to the esmsc set-up and helped in the data analysis and presentation	are medical students who contributed to the esmsc set-up and helped in the data analysis and presentation	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5385388	28413632	MS	2	are equal main contributors who drafted the manuscript and analyzed the data	are equal main contributors who drafted the manuscript and analyzed the data	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
5385388	28413632	NP	2	contributed to the conduction of the experiments as they hold expertise in animal model research	contributed to the conduction of the experiments as they hold expertise in animal model research	Performed the experiments	Investigation|Methodology	YES
5385388	28413632	NS	2	are medical students who contributed to the esmsc set-up and helped in the data analysis and presentation	are medical students who contributed to the esmsc set-up and helped in the data analysis and presentation	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5385388	28413632	PP	2	are equal main contributors who drafted the manuscript and analyzed the data	are equal main contributors who drafted the manuscript and analyzed the data	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
5385388	28413632	PT	2	conceived the study, and acted as senior authors, editing and providing feedback on the manuscript	conceived the study, and acted as senior authors, editing and providing feedback on the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5385388	28413632	TA	2	conceived the study, and acted as senior authors, editing and providing feedback on the manuscript	conceived the study, and acted as senior authors, editing and providing feedback on the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
4486488	26161388	Daisuke Okada	2	was involved in the study implementation and data analysis	was involved in the study implementation and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4486488	26161388	Nobuyasu Komasawa	2	were involved in the study design, study implementation, data analysis, and paper preparation	were involved in the study design, study implementation, data analysis, and paper preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
4486488	26161388	Sayuri Matsunami	2	were involved in the study design, study implementation, data analysis, and paper preparation	were involved in the study design, study implementation, data analysis, and paper preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
4486488	26161388	Shunsuke Fujiwara	2	were involved in the study design, study implementation, data analysis, and paper preparation	were involved in the study design, study implementation, data analysis, and paper preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
4486488	26161388	Toshiaki Minami	2	was involved in study design and paper preparation	was involved in study design and paper preparation	Conceived and designed the experiments	Methodology	YES
5874562	29518017	All	2	authors, i	authors, i	-	-	NO
5874562	29518017	D. Boyd	2	conceived and designed the paper|wrote and reviewed the final paper	conceived and designed the paper	Conceived and designed the experiments	Conceptualization	YES
5874562	29518017	D. Boyd	2	conceived and designed the paper|wrote and reviewed the final paper	wrote and reviewed the final paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5874562	29518017	Gennaro A. Paolella	2	conceived and designed the paper|wrote and reviewed the final paper	conceived and designed the paper	Conceived and designed the experiments	Conceptualization	YES
5874562	29518017	Gennaro A. Paolella	2	conceived and designed the paper|wrote and reviewed the final paper	wrote and reviewed the final paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5874562	29518017	Neeta K. Venepalli	2	wrote and reviewed the final paper	wrote and reviewed the final paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5874562	29518017	Sandra Cuellar	2	wrote and reviewed the final paper	wrote and reviewed the final paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5874562	29518017	Scott M. Wirth	2	wrote and reviewed the final paper	wrote and reviewed the final paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5874562	29518017	Stephanie Y. Crawford	2	conceived and designed the paper|wrote and reviewed the final paper	conceived and designed the paper	Conceived and designed the experiments	Conceptualization	YES
5874562	29518017	Stephanie Y. Crawford	2	conceived and designed the paper|wrote and reviewed the final paper	wrote and reviewed the final paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4405500	25897755	ABA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405500	25897755	ABA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405500	25897755	ABA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405500	25897755	ABA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405500	25897755	ABA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405500	25897755	ECH	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405500	25897755	ECH	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405500	25897755	ECH	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405500	25897755	EMB	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405500	25897755	JDB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405500	25897755	JDB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405500	25897755	JDB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405500	25897755	JDB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405500	25897755	JDB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405500	25897755	JEP	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4405500	25897755	JEP	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405500	25897755	JMT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405500	25897755	JMT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405500	25897755	JMT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405500	25897755	JMT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405500	25897755	MJY	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405500	25897755	MJY	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405500	25897755	MJY	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405500	25897755	MJY	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6334426	30651100	All authors	2	have critically reviewed and approved the manuscript and have participated sufficiently in the work to take public responsibility for its content|read and approved the final manuscript	have critically reviewed and approved the manuscript and have participated sufficiently in the work to take public responsibility for its content	Wrote the paper	Writing - Review & Editing	YES
6334426	30651100	All authors	2	have critically reviewed and approved the manuscript and have participated sufficiently in the work to take public responsibility for its content|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6334426	30651100	CEH	2	share the responsibility for the design of this study|conducted all the analyses|contributed to the interpretation of results	share the responsibility for the design of this study	Conceived and designed the experiments	Methodology	YES
6334426	30651100	CEH	2	share the responsibility for the design of this study|conducted all the analyses|contributed to the interpretation of results	conducted all the analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6334426	30651100	CEH	2	share the responsibility for the design of this study|conducted all the analyses|contributed to the interpretation of results	contributed to the interpretation of results	Analyzed the data	Formal analysis	YES
6334426	30651100	CMS	2	contributed to the interpretation of results	contributed to the interpretation of results	Analyzed the data	Formal analysis	YES
6334426	30651100	GPF	2	share the responsibility for the design of this study	share the responsibility for the design of this study	Conceived and designed the experiments	Methodology	YES
6334426	30651100	HIV	2	caregivers and their patients	caregivers and their patients	Performed the experiments	Investigation	YES
6334426	30651100	IRB	2	including a waiver of informed consent and authorization for use of protected health information	including a waiver of informed consent and authorization for use of protected health information	-	-	NO
6334426	30651100	JSF	2	share the responsibility for the design of this study|contributed to the interpretation of results|drafted the manuscript	share the responsibility for the design of this study	Conceived and designed the experiments	Methodology	YES
6334426	30651100	JSF	2	share the responsibility for the design of this study|contributed to the interpretation of results|drafted the manuscript	contributed to the interpretation of results	Analyzed the data	Formal analysis	YES
6334426	30651100	JSF	2	share the responsibility for the design of this study|contributed to the interpretation of results|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
6334426	30651100	KM	2	share the responsibility for the design of this study|contributed to the interpretation of results	share the responsibility for the design of this study	Conceived and designed the experiments	Methodology	YES
6334426	30651100	KM	2	share the responsibility for the design of this study|contributed to the interpretation of results	contributed to the interpretation of results	Analyzed the data	Formal analysis	YES
6334426	30651100	LB	2	conducted all the analyses|contributed to the interpretation of results|drafted the manuscript	conducted all the analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6334426	30651100	LB	2	conducted all the analyses|contributed to the interpretation of results|drafted the manuscript	contributed to the interpretation of results	Analyzed the data	Formal analysis	YES
6334426	30651100	LB	2	conducted all the analyses|contributed to the interpretation of results|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
6334426	30651100	LR	2	contributed to the interpretation of results	contributed to the interpretation of results	Analyzed the data	Formal analysis	YES
6334426	30651100	MSS	2	contributed to the interpretation of results	contributed to the interpretation of results	Analyzed the data	Formal analysis	YES
6334426	30651100	RH	2	share the responsibility for the design of this study|contributed to the interpretation of results	share the responsibility for the design of this study	Conceived and designed the experiments	Methodology	YES
6334426	30651100	RH	2	share the responsibility for the design of this study|contributed to the interpretation of results	contributed to the interpretation of results	Analyzed the data	Formal analysis	YES
6334426	30651100	V Healthcare	2	had no editorial control in the conduct of this study or the content of this article	had no editorial control in the conduct of this study or the content of this article	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
6334426	30651100	VV	2	share the responsibility for the design of this study	share the responsibility for the design of this study	Conceived and designed the experiments	Methodology	YES
5541012	28824671	HS	2	performed expression analysis	performed expression analysis	Performed the experiments	Investigation	YES
5541012	28824671	JB	2	performed expression analysis	performed expression analysis	Performed the experiments	Investigation	YES
5541012	28824671	RB	2	planned the study, drew the conclusions and contributed to the writing of the manuscript	planned the study, drew the conclusions and contributed to the writing of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5294834	28166727	BX	PLoS52	conducted the experiments|contributed the reagents/materials/analysis tools	conducted the experiments	Performed the experiments	Investigation	YES
5294834	28166727	BX	PLoS52	conducted the experiments|contributed the reagents/materials/analysis tools	contributed the reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5294834	28166727	HS	PLoS52	conceived and designed the experiments|analyzed the data|drafted the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5294834	28166727	HS	PLoS52	conceived and designed the experiments|analyzed the data|drafted the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5294834	28166727	HS	PLoS52	conceived and designed the experiments|analyzed the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5294834	28166727	JC	PLoS52	conceived and designed the experiments|analyzed the data|drafted the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5294834	28166727	JC	PLoS52	conceived and designed the experiments|analyzed the data|drafted the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5294834	28166727	JC	PLoS52	conceived and designed the experiments|analyzed the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5294834	28166727	KK	PLoS52	contributed the reagents/materials/analysis tools	contributed the reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5294834	28166727	SC	PLoS52	conducted the experiments|contributed the reagents/materials/analysis tools|drafted the manuscript	conducted the experiments	Performed the experiments	Investigation	YES
5294834	28166727	SC	PLoS52	conducted the experiments|contributed the reagents/materials/analysis tools|drafted the manuscript	contributed the reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5294834	28166727	SC	PLoS52	conducted the experiments|contributed the reagents/materials/analysis tools|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5294834	28166727	YW	PLoS52	conducted the experiments|contributed the reagents/materials/analysis tools	conducted the experiments	Performed the experiments	Investigation	YES
5294834	28166727	YW	PLoS52	conducted the experiments|contributed the reagents/materials/analysis tools	contributed the reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
3641305	23150149	Hideki Hara	1	Safety Monitoring Board Central Endpoint Evaluation Board	Safety Monitoring Board Central Endpoint Evaluation Board	-	Supervision	YES
3641305	23150149	Hideki Nishikawa	1	Safety Monitoring Board Central Endpoint Evaluation Board	Safety Monitoring Board Central Endpoint Evaluation Board	-	Supervision	YES
3641305	23150149	Masako Ohno	1	Principal investigator, chair	Principal investigator, chair	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
3641305	23150149	Ryoji Maekura	1	Safety Monitoring Board Central Endpoint Evaluation Board	Safety Monitoring Board Central Endpoint Evaluation Board	-	Supervision	YES
3641305	23150149	Soichiro Yokota	1	Principal investigator, chair	Principal investigator, chair	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
5388933	28417001	DW	2	contributed to the study design, data collections	contributed to the study design, data collections	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources	YES
5874563	29547577	CPOE	2	order sets, participated in the education of pharmacists and reviewed the manuscript before submission|order sets, coordinated education of pharmacists for patient-counseling and medication reconciliation and reviewed the manuscript before submission	order sets, participated in the education of pharmacists and reviewed the manuscript before submission	Wrote the paper	Writing - Review & Editing	YES
5874563	29547577	CPOE	2	order sets, participated in the education of pharmacists and reviewed the manuscript before submission|order sets, coordinated education of pharmacists for patient-counseling and medication reconciliation and reviewed the manuscript before submission	order sets, coordinated education of pharmacists for patient-counseling and medication reconciliation and reviewed the manuscript before submission	Wrote the paper	Project administration|Writing - Review & Editing	YES
5874563	29547577	H.A.	2	was the pharmacy director who organized pharmacy team, provided support to implement new services and reviewed the manuscript before submission	was the pharmacy director who organized pharmacy team, provided support to implement new services and reviewed the manuscript before submission	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5874563	29547577	S.I.	2	was the clinical pharmacist coordinator, participated in the development, implementation, assessment of data, co-investigator in champ-path study, analyzed data, drafted the manuscript and finalized before submission	was the clinical pharmacist coordinator, participated in the development, implementation, assessment of data, co-investigator in champ-path study, analyzed data, drafted the manuscript and finalized before submission	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Project administration|Writing - Original Draft	YES
4486493	26161394	Chunyan Li	2	made equal contributions to this study	made equal contributions to this study	-	-	NO
4486493	26161394	Dong Kang	2	made equal contributions to this study	made equal contributions to this study	-	-	NO
5392727	28443188	Argos Soares	7	writing, conception and study design, data analysis and final approval of the version to be submitted. Isabela de Alencar e Lombardi - writing, data collections, analysis and interpretation of data	writing, conception and study design, data analysis and final approval of the version to be submitted. Isabela de Alencar e Lombardi - writing, data collections, analysis and interpretation of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology	YES
5392727	28443188	Clarissa Santos Neto	7	picture art, writing and the conception and study design. Andreia Souto da Motta	picture art, writing and the conception and study design. Andreia Souto da Motta	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Visualization	YES
5392727	28443188	Matos Filho	7	writing, conception and study design, data analysis and final approval of the version to be submitted. Isabela de Alencar e Lombardi - writing, data collections, analysis and interpretation of data	writing, conception and study design, data analysis and final approval of the version to be submitted. Isabela de Alencar e Lombardi - writing, data collections, analysis and interpretation of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology	YES
5392727	28443188	Ronielly Araujo Rocha	7	writing and analysis and interpretation of data	writing and analysis and interpretation of data	Analyzed the data|Wrote the paper	Formal analysis	YES
4405530	25898134	AB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405530	25898134	AB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405530	25898134	AB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405530	25898134	AB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405530	25898134	ADA	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4405530	25898134	ADA	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4405530	25898134	ADA	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405530	25898134	AM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405530	25898134	AM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405530	25898134	AM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405530	25898134	CD	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4405530	25898134	DD	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405530	25898134	EVF	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405530	25898134	EVF	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405530	25898134	EVF	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405530	25898134	EVF	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405530	25898134	GB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4405530	25898134	GB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405530	25898134	GT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405530	25898134	GT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405530	25898134	GT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405530	25898134	GT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405530	25898134	GT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405530	25898134	MC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405530	25898134	PM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405530	25898134	PP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405530	25898134	VL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405530	25898134	VL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405530	25898134	VL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405530	25898134	VL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405530	25898134	VL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405530	25898134	VT	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5541053	28824691	ANE	2	collecting the phenotypical and gene expression analysis data	collecting the phenotypical and gene expression analysis data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5541053	28824691	ASa	2	drafted the manuscript, which was critically revised by all authors	drafted the manuscript, which was critically revised by all authors	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5541053	28824691	ASc	2	performed gas exchanges measurements and further analysis of data|drafted the manuscript, which was critically revised by all authors	performed gas exchanges measurements and further analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5541053	28824691	ASc	2	performed gas exchanges measurements and further analysis of data|drafted the manuscript, which was critically revised by all authors	drafted the manuscript, which was critically revised by all authors	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4814587	27029828	ADP	2	conceived and designed the study|analyzed and interpreted the data	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4814587	27029828	ADP	2	conceived and designed the study|analyzed and interpreted the data	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
4814587	27029828	All authors	2	critically revised the article for important intellectual content	critically revised the article for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4814587	27029828	BG	2	conceived and designed the study|analyzed and interpreted the data	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4814587	27029828	BG	2	conceived and designed the study|analyzed and interpreted the data	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
4814587	27029828	CJS	2	performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
4814587	27029828	EL	2	conceived and designed the study|analyzed and interpreted the data	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4814587	27029828	EL	2	conceived and designed the study|analyzed and interpreted the data	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
4814587	27029828	KAF	2	conceived and designed the study|analyzed and interpreted the data	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4814587	27029828	KAF	2	conceived and designed the study|analyzed and interpreted the data	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
4814587	27029828	MPG	2	conceived and designed the study|performed the model analysis and created the tables and figures|analyzed and interpreted the data|drafted the article	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4814587	27029828	MPG	2	conceived and designed the study|performed the model analysis and created the tables and figures|analyzed and interpreted the data|drafted the article	performed the model analysis and created the tables and figures	Performed the experiments	Investigation|Methodology|Visualization	YES
4814587	27029828	MPG	2	conceived and designed the study|performed the model analysis and created the tables and figures|analyzed and interpreted the data|drafted the article	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
4814587	27029828	MPG	2	conceived and designed the study|performed the model analysis and created the tables and figures|analyzed and interpreted the data|drafted the article	drafted the article	Wrote the paper	Writing - Original Draft	YES
4814587	27029828	PML	2	conceived and designed the study|performed the statistical analysis|analyzed and interpreted the data|drafted the article	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4814587	27029828	PML	2	conceived and designed the study|performed the statistical analysis|analyzed and interpreted the data|drafted the article	performed the statistical analysis	Analyzed the data	Formal analysis	YES
4814587	27029828	PML	2	conceived and designed the study|performed the statistical analysis|analyzed and interpreted the data|drafted the article	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
4814587	27029828	PML	2	conceived and designed the study|performed the statistical analysis|analyzed and interpreted the data|drafted the article	drafted the article	Wrote the paper	Writing - Original Draft	YES
4814587	27029828	RAP	2	conceived and designed the study|analyzed and interpreted the data	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4814587	27029828	RAP	2	conceived and designed the study|analyzed and interpreted the data	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
4814587	27029828	RLM	2	performed the model analysis and created the tables and figures|analyzed and interpreted the data	performed the model analysis and created the tables and figures	Performed the experiments	Investigation|Methodology|Visualization	YES
4814587	27029828	RLM	2	performed the model analysis and created the tables and figures|analyzed and interpreted the data	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
4814587	27029828	RPW	2	conceived and designed the study|analyzed and interpreted the data	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4814587	27029828	RPW	2	conceived and designed the study|analyzed and interpreted the data	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
4814587	27029828	VGV	2	conceived and designed the study|analyzed and interpreted the data	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4814587	27029828	VGV	2	conceived and designed the study|analyzed and interpreted the data	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5294865	28166723	NvM	2	designed the study and contributed to data analysis and in the elaboration of the manuscript	designed the study and contributed to data analysis and in the elaboration of the manuscript	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5294865	28166723	PF	2	designed the study and contributed to data analysis and in the elaboration of the manuscript	designed the study and contributed to data analysis and in the elaboration of the manuscript	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5294865	28166723	WGS	2	contributed to write the manuscript	contributed to write the manuscript	Wrote the paper	Writing - Original Draft	YES
6340167	30665440	All authors	2	revised the final version of the paper|read and approved the final manuscript	revised the final version of the paper	Wrote the paper	Writing - Review & Editing	YES
6340167	30665440	All authors	2	revised the final version of the paper|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6340167	30665440	BNM	2	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6340167	30665440	DB	2	conceived and designed the study|participated in data collection and analysis|drafted the original manuscript draft	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6340167	30665440	DB	2	conceived and designed the study|participated in data collection and analysis|drafted the original manuscript draft	participated in data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6340167	30665440	DB	2	conceived and designed the study|participated in data collection and analysis|drafted the original manuscript draft	drafted the original manuscript draft	Wrote the paper	Writing - Original Draft	YES
6340167	30665440	JS	2	conceived and designed the study|participated in data collection and analysis	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6340167	30665440	JS	2	conceived and designed the study|participated in data collection and analysis	participated in data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6340167	30665440	RM	2	participated in data collection and analysis	participated in data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6340167	30665440	SN	2	participated in data collection and analysis	participated in data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6024917	29659488	All authors	PLoS52	conceived and designed the experiments|revised the paper critically for important intellectual content and gave final approval	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6024917	29659488	All authors	PLoS52	conceived and designed the experiments|revised the paper critically for important intellectual content and gave final approval	revised the paper critically for important intellectual content and gave final approval	Wrote the paper	Writing - Review & Editing	YES
6024917	29659488	J.P.T.	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
6024917	29659488	P.M.	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
6024917	29659488	P.M.	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
6024917	29659488	Y.Z.Z.	PLoS52	analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
6024917	29659488	Y.Z.Z.	PLoS52	analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5394194	28443189	Akio Kanda	2	has been involved in drafting the manuscript and revising it critically for important intellectual content	has been involved in drafting the manuscript and revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5394194	28443189	Atsuhiko Mogami	2	has been involved in drafting the manuscript and revising it critically for important intellectual content	has been involved in drafting the manuscript and revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5394194	28443189	Itaru Morohashi	2	has been involved in drafting the manuscript and revising it critically for important intellectual content	has been involved in drafting the manuscript and revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5394194	28443189	Kaneko Kazuo	2	has been involved in drafting the manuscript and revising it critically for important intellectual content	has been involved in drafting the manuscript and revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5394194	28443189	Obayashi Osamu	2	has been involved in drafting the manuscript and revising it critically for important intellectual content	has been involved in drafting the manuscript and revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5394194	28443189	Takahito Miyake	2	has made substantial contributions to conception and design	has made substantial contributions to conception and design	Conceived and designed the experiments	Conceptualization	YES
3590640	23533361	F. Leung	2	have equally contributed to this study	have equally contributed to this study	-	-	NO
3590640	23533361	Z. Xiang	2	have equally contributed to this study	have equally contributed to this study	-	-	NO
5541054	28824692	CS	2	designed the study and supervised all of work	designed the study and supervised all of work	Conceived and designed the experiments	Methodology|Supervision	YES
5541054	28824692	FX	2	helped to reproduce cotton material	helped to reproduce cotton material	-	-	NO
5541054	28824692	JB	2	analyzed and interpreted data and wrote the manuscript	analyzed and interpreted data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5541054	28824692	JL	2	helped to reproduce cotton material	helped to reproduce cotton material	-	-	NO
5541054	28824692	LL	2	performed the cotton stable transformation	performed the cotton stable transformation	Performed the experiments	Investigation	YES
5541054	28824692	PS	2	helped to reproduce cotton material	helped to reproduce cotton material	-	-	NO
5541054	28824692	WG	2	analyzed and interpreted data and wrote the manuscript	analyzed and interpreted data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5541054	28824692	XT	2	performed the transient transformation analysis	performed the transient transformation analysis	Performed the experiments	Investigation	YES
4819069	27037140	CJ	2	analyzed the data as part of her masters in public health research and reviewed the manuscript	analyzed the data as part of her masters in public health research and reviewed the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4819069	27037140	CN	2	contributed to data interpretation and critically reviewed the manuscript	contributed to data interpretation and critically reviewed the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4819069	27037140	MC	2	designed the study, analyzed the data and prepared the manuscript	designed the study, analyzed the data and prepared the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4819069	27037140	SM	2	contributed to data coding and interpretation and critically reviewed the manuscript	contributed to data coding and interpretation and critically reviewed the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4405539	25897513	CCTH	PLoS5	Conceived and designed the experiments|Wrote the paper|Designed the microarray and qpcr|Performed the microarray and qpcr experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405539	25897513	CCTH	PLoS5	Conceived and designed the experiments|Wrote the paper|Designed the microarray and qpcr|Performed the microarray and qpcr experiments	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405539	25897513	CCTH	PLoS5	Conceived and designed the experiments|Wrote the paper|Designed the microarray and qpcr|Performed the microarray and qpcr experiments	Designed the microarray and qpcr	Conceived and designed the experiments|Performed the experiments	Investigation	YES
4405539	25897513	CCTH	PLoS5	Conceived and designed the experiments|Wrote the paper|Designed the microarray and qpcr|Performed the microarray and qpcr experiments	Performed the microarray and qpcr experiments	Performed the experiments	Investigation	YES
4405539	25897513	DM	PLoS5	Conceived and designed the experiments|Wrote the paper|Designed the microarray and qpcr	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405539	25897513	DM	PLoS5	Conceived and designed the experiments|Wrote the paper|Designed the microarray and qpcr	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405539	25897513	DM	PLoS5	Conceived and designed the experiments|Wrote the paper|Designed the microarray and qpcr	Designed the microarray and qpcr	Conceived and designed the experiments|Performed the experiments	Investigation	YES
4405539	25897513	HG	PLoS5	Conceived and designed the experiments|Wrote the paper|Designed the rna seq experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405539	25897513	HG	PLoS5	Conceived and designed the experiments|Wrote the paper|Designed the rna seq experiments	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405539	25897513	HG	PLoS5	Conceived and designed the experiments|Wrote the paper|Designed the rna seq experiments	Designed the rna seq experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4405539	25897513	KRJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Designed the rna seq experiments|Performed the bioinformatic analyses	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405539	25897513	KRJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Designed the rna seq experiments|Performed the bioinformatic analyses	Analyzed the data	Analyzed the data	Formal analysis	YES
4405539	25897513	KRJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Designed the rna seq experiments|Performed the bioinformatic analyses	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405539	25897513	KRJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Designed the rna seq experiments|Performed the bioinformatic analyses	Designed the rna seq experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4405539	25897513	KRJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Designed the rna seq experiments|Performed the bioinformatic analyses	Performed the bioinformatic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4405539	25897513	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Designed the microarray and qpcr|Performed the microarray and qpcr experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405539	25897513	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Designed the microarray and qpcr|Performed the microarray and qpcr experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405539	25897513	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Designed the microarray and qpcr|Performed the microarray and qpcr experiments	Designed the microarray and qpcr	Conceived and designed the experiments|Performed the experiments	Investigation	YES
4405539	25897513	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Designed the microarray and qpcr|Performed the microarray and qpcr experiments	Performed the microarray and qpcr experiments	Performed the experiments	Investigation	YES
4405539	25897513	SZH	PLoS5	Performed the experiments|Performed the microarray and qpcr experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405539	25897513	SZH	PLoS5	Performed the experiments|Performed the microarray and qpcr experiments	Performed the microarray and qpcr experiments	Performed the experiments	Investigation	YES
4405539	25897513	YDS	PLoS5	Conceived and designed the experiments|Performed the experiments|Designed the rna seq experiments|Performed the laser capture and rna seq experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405539	25897513	YDS	PLoS5	Conceived and designed the experiments|Performed the experiments|Designed the rna seq experiments|Performed the laser capture and rna seq experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405539	25897513	YDS	PLoS5	Conceived and designed the experiments|Performed the experiments|Designed the rna seq experiments|Performed the laser capture and rna seq experiments	Designed the rna seq experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4405539	25897513	YDS	PLoS5	Conceived and designed the experiments|Performed the experiments|Designed the rna seq experiments|Performed the laser capture and rna seq experiments	Performed the laser capture and rna seq experiments	Performed the experiments	Investigation	YES
4405539	25897513	YS	PLoS5	Conceived and designed the experiments|Performed the experiments|Designed the rna seq experiments|Performed the laser capture and rna seq experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405539	25897513	YS	PLoS5	Conceived and designed the experiments|Performed the experiments|Designed the rna seq experiments|Performed the laser capture and rna seq experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405539	25897513	YS	PLoS5	Conceived and designed the experiments|Performed the experiments|Designed the rna seq experiments|Performed the laser capture and rna seq experiments	Designed the rna seq experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4405539	25897513	YS	PLoS5	Conceived and designed the experiments|Performed the experiments|Designed the rna seq experiments|Performed the laser capture and rna seq experiments	Performed the laser capture and rna seq experiments	Performed the experiments	Investigation	YES
5295217	28166742	JWW	PLoS52	performed the experiment and analyzed the data	performed the experiment and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5295217	28166742	JX	PLoS52	performed the experiment and analyzed the data	performed the experiment and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5295217	28166742	LW	PLoS52	performed the experiment and analyzed the data	performed the experiment and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5295217	28166742	MQS	PLoS52	conceived and designed the experiments|wrote the paper|performed the experiment and analyzed the data	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5295217	28166742	MQS	PLoS52	conceived and designed the experiments|wrote the paper|performed the experiment and analyzed the data	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5295217	28166742	MQS	PLoS52	conceived and designed the experiments|wrote the paper|performed the experiment and analyzed the data	performed the experiment and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5295217	28166742	NF	PLoS52	performed the experiment and analyzed the data	performed the experiment and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5295217	28166742	XDL	PLoS52	conceived and designed the experiments|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5295217	28166742	XDL	PLoS52	conceived and designed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5295217	28166742	XL	PLoS52	wrote the paper|performed the experiment and analyzed the data	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5295217	28166742	XL	PLoS52	wrote the paper|performed the experiment and analyzed the data	performed the experiment and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5295217	28166742	ZJL	PLoS52	performed the experiment and analyzed the data	performed the experiment and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5295217	28166742	ZXC	PLoS52	performed the experiment and analyzed the data	performed the experiment and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3590685	23509435	M. Lainscak	2	participated in study design, results analysis, and paper preparation	participated in study design, results analysis, and paper preparation	Conceived and designed the experiments	Methodology	YES
3590685	23509435	M. Podbregar	2	carried out the experiments and wrote the paper	carried out the experiments and wrote the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3590685	23509435	O. Prelovsek	2	participated in study design, results analysis, and paper preparation	participated in study design, results analysis, and paper preparation	Conceived and designed the experiments	Methodology	YES
3590685	23509435	T. Mars	2	carried out the experiments and wrote the paper	carried out the experiments and wrote the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4486513	26161389	Tianyu Miao	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
4486513	26161389	Zhenru Liu	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
6024928	29865252	A.W.O.	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6024928	29865252	J.C.S.	2	contributed to the design of the study, provided comments for each step of the study, and reviewed the manuscript	contributed to the design of the study, provided comments for each step of the study, and reviewed the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
6024928	29865252	R.S.H.	2	contributed to the design of the study, provided comments for each step of the study, and reviewed the manuscript	contributed to the design of the study, provided comments for each step of the study, and reviewed the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
6343277	30670037	AFYP	2	performed all data processing and statistical analysis, generated all figures and drafted the manuscript	performed all data processing and statistical analysis, generated all figures and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Formal analysis|Investigation|Visualization|Writing - Original Draft	YES
6343277	30670037	AMC	2	all participants provided written informed consent	all participants provided written informed consent	Wrote the paper	Writing - Original Draft	YES
6343277	30670037	All authors	2	contributed to the writing of the report|read and approved the final manuscript	contributed to the writing of the report	Wrote the paper	-	YES
6343277	30670037	All authors	2	contributed to the writing of the report|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6343277	30670037	CK	2	conceived of the study and contributed to study design and data interpretation	conceived of the study and contributed to study design and data interpretation	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Methodology|Resources	YES
6343277	30670037	DR	2	samples and samples from the march study were collected with informed consent provided by parent /guardian	samples and samples from the march study were collected with informed consent provided by parent /guardian	Performed the experiments	Investigation	YES
6343277	30670037	EJA	2	conceived of the study and contributed to study design and data interpretation	conceived of the study and contributed to study design and data interpretation	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Methodology|Resources	YES
6343277	30670037	EN	2	led the data collection activities	led the data collection activities	Performed the experiments	Investigation	YES
6343277	30670037	FK	2	conceived of the study and contributed to study design and data interpretation	conceived of the study and contributed to study design and data interpretation	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Methodology|Resources	YES
6343277	30670037	IN	2	conceived of the study and contributed to study design and data interpretation	conceived of the study and contributed to study design and data interpretation	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Methodology|Resources	YES
6343277	30670037	MA	2	contributed to the phylogenetic analysis of the data	contributed to the phylogenetic analysis of the data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
6343277	30670037	MEQ-M	2	conceived of the study and contributed to study design and data interpretation	conceived of the study and contributed to study design and data interpretation	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Methodology|Resources	YES
6343277	30670037	RG	2	led the data collection activities	led the data collection activities	Performed the experiments	Investigation	YES
6343277	30670037	Study Team	2	but restrictions apply to the availability of these data, and so are not publicly available	but restrictions apply to the availability of these data, and so are not publicly available	-	-	NO
6343277	30670037	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
6343277	30670037	UDRS	2	provided access to anonymized clinical and sequence databases	provided access to anonymized clinical and sequence databases	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources|Software	YES
6343277	30670037	Ugandan Drug Resistance	2	but restrictions apply to the availability of these data, and so are not publicly available	but restrictions apply to the availability of these data, and so are not publicly available	-	-	NO
5541062	28824661	IL	2	executed experiments	executed experiments	Performed the experiments	Investigation	YES
5541062	28824661	PH	2	designed the experiments, interpreted the data and wrote the manuscript	designed the experiments, interpreted the data and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5541062	28824661	SC	2	executed the experiments, interpreted the data and wrote the manuscript	executed the experiments, interpreted the data and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5297046	28173754	AZ	PLoS52	performed experiments|analysed data|wrote the paper	performed experiments	Performed the experiments	Investigation	YES
5297046	28173754	AZ	PLoS52	performed experiments|analysed data|wrote the paper	analysed data	Analyzed the data	Formal analysis	YES
5297046	28173754	AZ	PLoS52	performed experiments|analysed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5297046	28173754	ESD	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5297046	28173754	IKG	PLoS52	supervised data analysis	supervised data analysis	Analyzed the data	Formal analysis|Supervision	YES
5297046	28173754	WJP	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4821890	27049052	AA	2	contributed to acquisition of data	contributed to acquisition of data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4821890	27049052	AM	2	contributed to acquisition of data	contributed to acquisition of data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4821890	27049052	AR	2	contributed to acquisition of data	contributed to acquisition of data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4821890	27049052	All	2	others were involved in drafting the manuscript or revising it critically for important intellectual content	others were involved in drafting the manuscript or revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4821890	27049052	BG	2	contributed to acquisition of data	contributed to acquisition of data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4821890	27049052	CC	2	contributed to acquisition of data	contributed to acquisition of data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4821890	27049052	CMG	2	made substantial contributions to conception and design|analysed and interpreted the data	made substantial contributions to conception and design	Conceived and designed the experiments	Conceptualization	YES
4821890	27049052	CMG	2	made substantial contributions to conception and design|analysed and interpreted the data	analysed and interpreted the data	Analyzed the data	Formal analysis	YES
4821890	27049052	CW	2	contributed to acquisition of data	contributed to acquisition of data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4821890	27049052	DBH	2	made substantial contributions to conception and design|analysed and interpreted the data	made substantial contributions to conception and design	Conceived and designed the experiments	Conceptualization	YES
4821890	27049052	DBH	2	made substantial contributions to conception and design|analysed and interpreted the data	analysed and interpreted the data	Analyzed the data	Formal analysis	YES
4821890	27049052	DP	2	contributed to acquisition of data	contributed to acquisition of data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4821890	27049052	FMC	2	contributed to acquisition of data	contributed to acquisition of data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4821890	27049052	JET	2	contributed to acquisition of data	contributed to acquisition of data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4821890	27049052	JSM	2	contributed to acquisition of data	contributed to acquisition of data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4821890	27049052	JWP	2	contributed to acquisition of data	contributed to acquisition of data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4821890	27049052	KB	2	contributed to acquisition of data	contributed to acquisition of data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4821890	27049052	KNA	2	made substantial contributions to conception and design|analysed and interpreted the data	made substantial contributions to conception and design	Conceived and designed the experiments	Conceptualization	YES
4821890	27049052	KNA	2	made substantial contributions to conception and design|analysed and interpreted the data	analysed and interpreted the data	Analyzed the data	Formal analysis	YES
4821890	27049052	MAH	2	contributed to acquisition of data	contributed to acquisition of data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4821890	27049052	MJG	2	contributed to acquisition of data	contributed to acquisition of data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4821890	27049052	MJW	2	contributed to acquisition of data	contributed to acquisition of data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4821890	27049052	MK	2	contributed to acquisition of data	contributed to acquisition of data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4821890	27049052	PC	2	contributed to acquisition of data	contributed to acquisition of data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4821890	27049052	PFR	2	made substantial contributions to conception and design|analysed and interpreted the data	made substantial contributions to conception and design	Conceived and designed the experiments	Conceptualization	YES
4821890	27049052	PFR	2	made substantial contributions to conception and design|analysed and interpreted the data	analysed and interpreted the data	Analyzed the data	Formal analysis	YES
4821890	27049052	RH	2	contributed to acquisition of data	contributed to acquisition of data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4821890	27049052	SBR	2	contributed to acquisition of data	contributed to acquisition of data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4821890	27049052	TRS	2	contributed to acquisition of data	contributed to acquisition of data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4405540	25897502	SN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405540	25897502	SN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405540	25897502	SN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405540	25897502	SN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405540	25897502	SW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405540	25897502	SW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405540	25897502	SW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405540	25897502	TYN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405540	25897502	TYN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405540	25897502	TYN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405540	25897502	TYN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405540	25897502	TYN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6024955	29890738	A.D.	2	provided comments for each step of the study	provided comments for each step of the study	-	-	NO
6024955	29890738	All authors	2	commented on the manuscript and approved the submitted version for publication	commented on the manuscript and approved the submitted version for publication	-	-	NO
6024955	29890738	B.H.	2	did the analyses and wrote the manuscript	did the analyses and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6024955	29890738	J.L.	2	contributed to patient recruitment	contributed to patient recruitment	Performed the experiments	Investigation	YES
6024955	29890738	J.M.	2	provided comments for each step of the study	provided comments for each step of the study	-	-	NO
6024955	29890738	L.G.	2	designed the study and supervised each study steps	designed the study and supervised each study steps	Conceived and designed the experiments	Methodology|Supervision	YES
6024955	29890738	L.P.	2	contributed to patient recruitment	contributed to patient recruitment	Performed the experiments	Investigation	YES
6024955	29890738	S.C.	2	did the analyses and wrote the manuscript	did the analyses and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6024955	29890738	S.L.	2	designed the study and supervised each study steps	designed the study and supervised each study steps	Conceived and designed the experiments	Methodology|Supervision	YES
5408500	28487765	Hidenori Kawasaki	7	study concept	study concept	Conceived and designed the experiments	Conceptualization	YES
5408500	28487765	Kazuaki Kushi	7	data collection	data collection	Performed the experiments	Investigation	YES
5408500	28487765	Naohiro Taira	7	writing the paper	writing the paper	Wrote the paper	Writing - Original Draft	YES
5408500	28487765	Takaharu Ichi	7	data collection	data collection	Performed the experiments	Investigation	YES
5408500	28487765	Tomofumi Yohena	7	study design	study design	Conceived and designed the experiments	Methodology	YES
5408500	28487765	Tomonori Furugen	7	data collection	data collection	Performed the experiments	Investigation	YES
5408500	28487765	Tsutomu Kawabata	7	study design	study design	Conceived and designed the experiments	Methodology	YES
6364409	30722787	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6364409	30722787	CAPES	2	for the postgraduate scholarship	for the postgraduate scholarship	-	-	NO
6364409	30722787	Clinical Analysis Laboratory	2	of the state university of maringa, for processing and analyzing of samples	of the state university of maringa, for processing and analyzing of samples	Analyzed the data	Data curation|Formal analysis	YES
6364409	30722787	Clinical Immunology	2	of the state university of maringa, for processing and analyzing of samples	of the state university of maringa, for processing and analyzing of samples	Analyzed the data	Data curation|Formal analysis	YES
6364409	30722787	DAB	2	contributed for the study conception and design|analyzed and interpreted the data and revised the manuscript critically for important intellectual content	contributed for the study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6364409	30722787	DAB	2	contributed for the study conception and design|analyzed and interpreted the data and revised the manuscript critically for important intellectual content	analyzed and interpreted the data and revised the manuscript critically for important intellectual content	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
6364409	30722787	EMVR	2	collaborated to sample and data collection|contributed for the study conception and design	collaborated to sample and data collection	Performed the experiments	Investigation	YES
6364409	30722787	EMVR	2	collaborated to sample and data collection|contributed for the study conception and design	contributed for the study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6364409	30722787	JCCF	2	contributed for the study conception and design	contributed for the study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6364409	30722787	JRCD	2	collaborated to sample and data collection	collaborated to sample and data collection	Performed the experiments	Investigation	YES
6364409	30722787	LDB	2	collaborated to sample and data collection, performed molecular biology experiments and statistical analyses, and contributed to the writing of the manuscript	collaborated to sample and data collection, performed molecular biology experiments and statistical analyses, and contributed to the writing of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6364409	30722787	LTU	2	collaborated to sample and data collection	collaborated to sample and data collection	Performed the experiments	Investigation	YES
6364409	30722787	PHC	2	helped to perform dna extraction	helped to perform dna extraction	Performed the experiments	Investigation	YES
6364409	30722787	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
6364409	30722787	VAFM	2	collaborated to sample and data collection	collaborated to sample and data collection	Performed the experiments	Investigation	YES
4405541	25898010	CH	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405541	25898010	HY	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405541	25898010	JZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405541	25898010	MZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405541	25898010	XC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405541	25898010	YL	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405541	25898010	YM	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4405541	25898010	YMZ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5541085	28824681	AM	2	collected the literatures and wrote the manuscript	collected the literatures and wrote the manuscript	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5541085	28824681	YA	2	proof-read, finalized, and approved the manuscript	proof-read, finalized, and approved the manuscript	Wrote the paper	Writing - Review & Editing	YES
5297047	28173755	AV	2	performed the rna seq analysis	performed the rna seq analysis	Performed the experiments	Investigation	YES
5297047	28173755	AY	2	performed in vivo validation of the cell line behavior	performed in vivo validation of the cell line behavior	Performed the experiments	Investigation|Validation	YES
5297047	28173755	EK	2	derived and maintained the zmelr1 line|performed all of the drug response, dna and rna preparations	derived and maintained the zmelr1 line	-	-	NO
5297047	28173755	EK	2	derived and maintained the zmelr1 line|performed all of the drug response, dna and rna preparations	performed all of the drug response, dna and rna preparations	Performed the experiments	Investigation	YES
5297047	28173755	EL	2	derived and maintained the zmelr1 line	derived and maintained the zmelr1 line	-	-	NO
5297047	28173755	MA	2	performed the circos plot constructions	performed the circos plot constructions	Performed the experiments	Investigation	YES
5297047	28173755	OE	2	performed the rna seq analysis	performed the rna seq analysis	Performed the experiments	Investigation	YES
5297047	28173755	RMW	2	conceived the study design	conceived the study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5297047	28173755	TSV	2	performed all of the drug response, dna and rna preparations	performed all of the drug response, dna and rna preparations	Performed the experiments	Investigation	YES
5297047	28173755	WL	2	performed the dna sequencing and variant analysis	performed the dna sequencing and variant analysis	Performed the experiments	Investigation	YES
5423324	28507732	All the three authors	5	substantially contributed to effectively construct the article [BA	substantially contributed to effectively construct the article [BA	Performed the experiments	Investigation	YES
6024976	29880765	E.B.	2	conceptualized the study|conducted the data analysis and prepared the manuscript	conceptualized the study	Conceived and designed the experiments	Conceptualization	YES
6024976	29880765	E.B.	2	conceptualized the study|conducted the data analysis and prepared the manuscript	conducted the data analysis and prepared the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6024976	29880765	E.G.	2	conceptualized the study|provided substantial input to the manuscript	conceptualized the study	Conceived and designed the experiments	Conceptualization	YES
6024976	29880765	E.G.	2	conceptualized the study|provided substantial input to the manuscript	provided substantial input to the manuscript	-	-	NO
6024976	29880765	H.K.	2	provided strategic input in the design phase|conceptualized the drug use interview of the initial degs1 study, managed the data, and provided the data for the present study|critically reviewed the manuscript	provided strategic input in the design phase	Conceived and designed the experiments	-	YES
6024976	29880765	H.K.	2	provided strategic input in the design phase|conceptualized the drug use interview of the initial degs1 study, managed the data, and provided the data for the present study|critically reviewed the manuscript	conceptualized the drug use interview of the initial degs1 study, managed the data, and provided the data for the present study	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Data curation|Investigation|Project administration|Resources	YES
6024976	29880765	H.K.	2	provided strategic input in the design phase|conceptualized the drug use interview of the initial degs1 study, managed the data, and provided the data for the present study|critically reviewed the manuscript	critically reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
4824870	27056361	All authors	2	reviewed and approved the final version	reviewed and approved the final version	-	-	NO
4824870	27056361	JA	2	conceived the study design|carried out the review|wrote the first draft	conceived the study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4824870	27056361	JA	2	conceived the study design|carried out the review|wrote the first draft	carried out the review	Performed the experiments	Investigation	YES
4824870	27056361	JA	2	conceived the study design|carried out the review|wrote the first draft	wrote the first draft	Wrote the paper	Writing - Original Draft	YES
4824870	27056361	JM	2	conceived the study design|double-screened most included papers|commented on all subsequent drafts	conceived the study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4824870	27056361	JM	2	conceived the study design|double-screened most included papers|commented on all subsequent drafts	double-screened most included papers	Performed the experiments	Investigation	YES
4824870	27056361	JM	2	conceived the study design|double-screened most included papers|commented on all subsequent drafts	commented on all subsequent drafts	Wrote the paper	Writing - Original Draft	YES
5297132	28173752	H.D.L.	2	designed the study, wrote the paper and did the revision	designed the study, wrote the paper and did the revision	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5297132	28173752	J.M.X.	2	contributed to discussion	contributed to discussion	-	-	NO
5297132	28173752	K.L.	2	contributed to discussion	contributed to discussion	-	-	NO
5297132	28173752	L.J.L.	2	performed the computation	performed the computation	Performed the experiments	Formal analysis|Investigation	YES
5297132	28173752	X.S.	2	contributed to discussion	contributed to discussion	-	-	NO
5297132	28173752	Z.H.Q.	2	contributed to discussion	contributed to discussion	-	-	NO
6385432	30795780	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6385432	30795780	JAEN	2	conducted all resistance assays and analyses	conducted all resistance assays and analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6385432	30795780	JSC	2	conducted data analysis and contributed to drafting	conducted data analysis and contributed to drafting	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6385432	30795780	MCH	2	drafted the initial manuscript|were all investigators on the primary clinical trial that produced this data	drafted the initial manuscript	Wrote the paper	Writing - Original Draft	YES
6385432	30795780	MCH	2	drafted the initial manuscript|were all investigators on the primary clinical trial that produced this data	were all investigators on the primary clinical trial that produced this data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6385432	30795780	SER	2	drafted the initial manuscript|were all investigators on the primary clinical trial that produced this data	drafted the initial manuscript	Wrote the paper	Writing - Original Draft	YES
6385432	30795780	SER	2	drafted the initial manuscript|were all investigators on the primary clinical trial that produced this data	were all investigators on the primary clinical trial that produced this data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6385432	30795780	SP	2	were all investigators on the primary clinical trial that produced this data	were all investigators on the primary clinical trial that produced this data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6385432	30795780	WCM	2	were all investigators on the primary clinical trial that produced this data	were all investigators on the primary clinical trial that produced this data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4405542	25898019	DF	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405542	25898019	DF	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405542	25898019	DF	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405542	25898019	L-PR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405542	25898019	L-PR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405542	25898019	L-PR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405542	25898019	TD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405542	25898019	TD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405542	25898019	TD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4384222	25861405	BJZ	2	participated in the design of the study and developed the ct scanning protocol	participated in the design of the study and developed the ct scanning protocol	Conceived and designed the experiments	Methodology	YES
4384222	25861405	HPWvJ	2	initiated the study|wrote the manuscript	initiated the study	Conceived and designed the experiments	Conceptualization	YES
4384222	25861405	HPWvJ	2	initiated the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4384222	25861405	REW	2	participated in the design of the study and developed the ct scanning protocol|wrote the manuscript	participated in the design of the study and developed the ct scanning protocol	Conceived and designed the experiments	Methodology	YES
4384222	25861405	REW	2	participated in the design of the study and developed the ct scanning protocol|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4384222	25861405	RPD	2	participated in the design of the study and developed the ct scanning protocol	participated in the design of the study and developed the ct scanning protocol	Conceived and designed the experiments	Methodology	YES
6024982	29690577	R.T.	2	supported data analysis and helped draft the manuscript	supported data analysis and helped draft the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6024982	29690577	S.Y.	2	was the chief investigator and project lead	was the chief investigator and project lead	-	-	NO
4486741	26161419	John P. Dowling	2	carried out certain experiments and extensive literature search and drafted and critically revised the paper	carried out certain experiments and extensive literature search and drafted and critically revised the paper	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
4486741	26161419	Senthamil R. Selvan	2	conceived the idea of adherent enrichment and expansion of nk cells, designed and carried out experiments, acquired and analyzed the data, and prepared and critically revised the paper	conceived the idea of adherent enrichment and expansion of nk cells, designed and carried out experiments, acquired and analyzed the data, and prepared and critically revised the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
4827101	27065108	BES	2	made substantial contributions to the conception and design of the study, as well as interpretation of data|analyzed it	made substantial contributions to the conception and design of the study, as well as interpretation of data	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Methodology|Resources	YES
4827101	27065108	BES	2	made substantial contributions to the conception and design of the study, as well as interpretation of data|analyzed it	analyzed it	Analyzed the data	Formal analysis	YES
4827101	27065108	CC	2	made substantial contributions to the conception and design of the study, as well as interpretation of data|analyzed it|drafted the article	made substantial contributions to the conception and design of the study, as well as interpretation of data	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Methodology|Resources	YES
4827101	27065108	CC	2	made substantial contributions to the conception and design of the study, as well as interpretation of data|analyzed it|drafted the article	analyzed it	Analyzed the data	Formal analysis	YES
4827101	27065108	CC	2	made substantial contributions to the conception and design of the study, as well as interpretation of data|analyzed it|drafted the article	drafted the article	Wrote the paper	Writing - Original Draft	YES
4827101	27065108	CCM	2	made substantial contributions to the conception and design of the study, as well as interpretation of data|drafted the article	made substantial contributions to the conception and design of the study, as well as interpretation of data	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Methodology|Resources	YES
4827101	27065108	CCM	2	made substantial contributions to the conception and design of the study, as well as interpretation of data|drafted the article	drafted the article	Wrote the paper	Writing - Original Draft	YES
4827101	27065108	CPC	2	acquired the data	acquired the data	Performed the experiments	Investigation	YES
4827101	27065108	DH	2	acquired the data	acquired the data	Performed the experiments	Investigation	YES
4827101	27065108	DP	2	acquired the data	acquired the data	Performed the experiments	Investigation	YES
4827101	27065108	FR	2	acquired the data	acquired the data	Performed the experiments	Investigation	YES
4827101	27065108	JWP	2	acquired the data	acquired the data	Performed the experiments	Investigation	YES
4827101	27065108	PBZ	2	acquired the data	acquired the data	Performed the experiments	Investigation	YES
4827101	27065108	PC	2	acquired the data	acquired the data	Performed the experiments	Investigation	YES
4827101	27065108	PFR	2	made substantial contributions to the conception and design of the study, as well as interpretation of data|analyzed it|drafted the article	made substantial contributions to the conception and design of the study, as well as interpretation of data	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Methodology|Resources	YES
4827101	27065108	PFR	2	made substantial contributions to the conception and design of the study, as well as interpretation of data|analyzed it|drafted the article	analyzed it	Analyzed the data	Formal analysis	YES
4827101	27065108	PFR	2	made substantial contributions to the conception and design of the study, as well as interpretation of data|analyzed it|drafted the article	drafted the article	Wrote the paper	Writing - Original Draft	YES
4827101	27065108	RBD	2	acquired the data	acquired the data	Performed the experiments	Investigation	YES
4827101	27065108	all authors	2	revised it critically for important intellectual content	revised it critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5541250	28824696	BM	2	conducted the plant-growth experiments|carried out the data analyses	conducted the plant-growth experiments	Performed the experiments	Investigation	YES
5541250	28824696	BM	2	conducted the plant-growth experiments|carried out the data analyses	carried out the data analyses	Analyzed the data	Formal analysis	YES
5541250	28824696	FB	2	carried out the data analyses	carried out the data analyses	Analyzed the data	Formal analysis	YES
5541250	28824696	KG	2	conducted the plant-growth experiments	conducted the plant-growth experiments	Performed the experiments	Investigation	YES
5541250	28824696	NM	2	conceived the research program	conceived the research program	Conceived and designed the experiments	Conceptualization	YES
5541250	28824696	PK	2	conceived the research program|conducted the plant-growth experiments|carried out the data analyses|wrote the first draft of the article to which all other authors contributed	conceived the research program	Conceived and designed the experiments	Conceptualization	YES
5541250	28824696	PK	2	conceived the research program|conducted the plant-growth experiments|carried out the data analyses|wrote the first draft of the article to which all other authors contributed	conducted the plant-growth experiments	Performed the experiments	Investigation	YES
5541250	28824696	PK	2	conceived the research program|conducted the plant-growth experiments|carried out the data analyses|wrote the first draft of the article to which all other authors contributed	carried out the data analyses	Analyzed the data	Formal analysis	YES
5541250	28824696	PK	2	conceived the research program|conducted the plant-growth experiments|carried out the data analyses|wrote the first draft of the article to which all other authors contributed	wrote the first draft of the article to which all other authors contributed	Wrote the paper	Writing - Original Draft	YES
5541250	28824696	PR	2	conceived the research program	conceived the research program	Conceived and designed the experiments	Conceptualization	YES
5541250	28824696	PW	2	conceived the research program|carried out the data analyses	conceived the research program	Conceived and designed the experiments	Conceptualization	YES
5541250	28824696	PW	2	conceived the research program|carried out the data analyses	carried out the data analyses	Analyzed the data	Formal analysis	YES
4405543	25898203	AH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405543	25898203	AH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405543	25898203	AH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405543	25898203	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Obtained funding	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405543	25898203	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Obtained funding	Performed the experiments	Performed the experiments	Investigation	YES
4405543	25898203	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Obtained funding	Analyzed the data	Analyzed the data	Formal analysis	YES
4405543	25898203	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Obtained funding	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405543	25898203	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Obtained funding	Obtained funding	-	Funding acquisition	YES
4405543	25898203	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Obtained funding	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405543	25898203	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Obtained funding	Performed the experiments	Performed the experiments	Investigation	YES
4405543	25898203	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Obtained funding	Analyzed the data	Analyzed the data	Formal analysis	YES
4405543	25898203	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Obtained funding	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405543	25898203	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Obtained funding	Obtained funding	-	Funding acquisition	YES
4405543	25898203	SC	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405543	25898203	SC	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405543	25898203	WE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405543	25898203	WE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405543	25898203	WE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405543	25898203	WE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3832778	23955175	All authors	2	provided substantial contributions to the conception and design of the clinical trials and were responsible for analysis and interpretation of data contained within this manuscript|revised the manuscript critically for important intellectual content, and read and approved the final manuscript	provided substantial contributions to the conception and design of the clinical trials and were responsible for analysis and interpretation of data contained within this manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Methodology|Resources	YES
3832778	23955175	All authors	2	provided substantial contributions to the conception and design of the clinical trials and were responsible for analysis and interpretation of data contained within this manuscript|revised the manuscript critically for important intellectual content, and read and approved the final manuscript	revised the manuscript critically for important intellectual content, and read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
3832778	23955175	William Kielbasa	2	prepared the initial draft of the manuscript	prepared the initial draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
6420760	30876476	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6420760	30876476	BYL	PLoS52	designed the study and provided the correlative knowledge|drafted of the manuscript	designed the study and provided the correlative knowledge	Conceived and designed the experiments	Methodology	YES
6420760	30876476	BYL	PLoS52	designed the study and provided the correlative knowledge|drafted of the manuscript	drafted of the manuscript	Wrote the paper	Writing - Original Draft	YES
6420760	30876476	BZ	PLoS52	collected and provided the data, including data extraction and data cleaning	collected and provided the data, including data extraction and data cleaning	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Investigation|Resources	YES
6420760	30876476	CXZ	PLoS52	collected and provided the data, including data extraction and data cleaning|drafted of the manuscript	collected and provided the data, including data extraction and data cleaning	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Investigation|Resources	YES
6420760	30876476	CXZ	PLoS52	collected and provided the data, including data extraction and data cleaning|drafted of the manuscript	drafted of the manuscript	Wrote the paper	Writing - Original Draft	YES
6420760	30876476	CYN	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
6420760	30876476	GHL	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
6420760	30876476	HL	PLoS52	designed the study and provided the correlative knowledge	designed the study and provided the correlative knowledge	Conceived and designed the experiments	Methodology	YES
6420760	30876476	JGH	PLoS52	designed the study and provided the correlative knowledge	designed the study and provided the correlative knowledge	Conceived and designed the experiments	Methodology	YES
6420760	30876476	JJJ	PLoS52	designed the study and provided the correlative knowledge	designed the study and provided the correlative knowledge	Conceived and designed the experiments	Methodology	YES
6420760	30876476	JL	PLoS52	collected and provided the data, including data extraction and data cleaning	collected and provided the data, including data extraction and data cleaning	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Investigation|Resources	YES
6420760	30876476	JZL	PLoS52	collected and provided the data, including data extraction and data cleaning	collected and provided the data, including data extraction and data cleaning	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Investigation|Resources	YES
6420760	30876476	LY	PLoS52	designed the study and provided the correlative knowledge	designed the study and provided the correlative knowledge	Conceived and designed the experiments	Methodology	YES
6420760	30876476	NZ	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
6420760	30876476	PJP	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
6420760	30876476	RFC	PLoS52	collected and provided the data, including data extraction and data cleaning	collected and provided the data, including data extraction and data cleaning	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Investigation|Resources	YES
6420760	30876476	XH	PLoS52	analyzed the data|drafted of the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
6420760	30876476	XH	PLoS52	analyzed the data|drafted of the manuscript	drafted of the manuscript	Wrote the paper	Writing - Original Draft	YES
6420760	30876476	XL	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
6420760	30876476	XWP	PLoS52	collected and provided the data, including data extraction and data cleaning	collected and provided the data, including data extraction and data cleaning	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Investigation|Resources	YES
6420760	30876476	YYL	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
6420760	30876476	ZYS	PLoS52	designed the study and provided the correlative knowledge	designed the study and provided the correlative knowledge	Conceived and designed the experiments	Methodology	YES
5299677	28178938	DM	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5299677	28178938	JE	2	carried out the rna and mirna profiling	carried out the rna and mirna profiling	Performed the experiments	Investigation	YES
5299677	28178938	JR	2	participated in the design of the study and performed the statistical analysis	participated in the design of the study and performed the statistical analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5299677	28178938	KT	2	carried out the rna and mirna profiling	carried out the rna and mirna profiling	Performed the experiments	Investigation	YES
5299677	28178938	ML	2	participated in the design of the study and performed the statistical analysis	participated in the design of the study and performed the statistical analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5299677	28178938	PM	2	carried out the rna and mirna profiling|participated in the design of the study and performed the statistical analysis	carried out the rna and mirna profiling	Performed the experiments	Investigation	YES
5299677	28178938	PM	2	carried out the rna and mirna profiling|participated in the design of the study and performed the statistical analysis	participated in the design of the study and performed the statistical analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5299677	28178938	RJ	2	participated in the design of the study and performed the statistical analysis	participated in the design of the study and performed the statistical analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5299677	28178938	RS	2	helped to draft the manuscript	helped to draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5299677	28178938	SL	2	participated in the design of the study and performed the statistical analysis	participated in the design of the study and performed the statistical analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5299677	28178938	TH	2	participated in the design of the study and performed the statistical analysis	participated in the design of the study and performed the statistical analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5299677	28178938	VM	2	helped to draft the manuscript	helped to draft the manuscript	Wrote the paper	Writing - Original Draft	YES
6024993	29642377	A.M.	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6024993	29642377	A.M.	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
6024993	29642377	A.M.	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
6024993	29642377	B.M.	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6024993	29642377	E.A.B.	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
6024993	29642377	E.A.B.	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
6024993	29642377	H.J.	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6024993	29642377	H.J.	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
6024993	29642377	H.J.	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
6024993	29642377	H.J.	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6024993	29642377	J.G.	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6024993	29642377	J.G.	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
6024993	29642377	J.G.	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
6024993	29642377	L.W.	PLoS52	analyzed the data|contributed analysis tools|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
6024993	29642377	L.W.	PLoS52	analyzed the data|contributed analysis tools|wrote the paper	contributed analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
6024993	29642377	L.W.	PLoS52	analyzed the data|contributed analysis tools|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6024993	29642377	T.J.	PLoS52	analyzed the data|contributed analysis tools	analyzed the data	Analyzed the data	Formal analysis	YES
6024993	29642377	T.J.	PLoS52	analyzed the data|contributed analysis tools	contributed analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4829657	27072532	ASV	2	contributed to data analysis and manuscript preparation	contributed to data analysis and manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4829657	27072532	BMB	2	contributed to data analysis and manuscript preparation	contributed to data analysis and manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4829657	27072532	JB	2	contributed to data analysis and manuscript preparation	contributed to data analysis and manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4829657	27072532	NL	2	contributed to data analysis and manuscript preparation	contributed to data analysis and manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5440755	28560032	Gang Wu	1	Data collection	Data collection	Performed the experiments	Investigation	YES
5440755	28560032	Hongshan Zhong	1	Data analysis	Data analysis	Analyzed the data	Formal analysis	YES
5440755	28560032	Ke Xu	1	Study concept or design	Study concept or design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5440755	28560032	Yonghua Bi	1	Animal study|Writing the paper	Animal study	Performed the experiments	Investigation	YES
5440755	28560032	Yonghua Bi	1	Animal study|Writing the paper	Writing the paper	Wrote the paper	Writing - Original Draft	YES
5440755	28560032	Zepeng Yu	1	Revise the paper	Revise the paper	Wrote the paper	Writing - Review & Editing	YES
5541829	28824675	AE	2	performed lipidomics analysis	performed lipidomics analysis	Performed the experiments	Investigation	YES
5541829	28824675	All authors	2	were involved in the data analysis and preparation of manuscript	were involved in the data analysis and preparation of manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5541829	28824675	JP	2	conceived the idea and designed the experiments	conceived the idea and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5541829	28824675	MT	2	performed proteomics analysis	performed proteomics analysis	Performed the experiments	Investigation	YES
5541829	28824675	PC	2	performed proteomics analysis	performed proteomics analysis	Performed the experiments	Investigation	YES
5541829	28824675	PS	2	performed lipidomics analysis	performed lipidomics analysis	Performed the experiments	Investigation	YES
5541829	28824675	QL	2	conceived the idea and designed the experiments	conceived the idea and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5541829	28824675	RW	2	performed microscopy analysis|conceived the idea and designed the experiments	performed microscopy analysis	Performed the experiments	Investigation	YES
5541829	28824675	RW	2	performed microscopy analysis|conceived the idea and designed the experiments	conceived the idea and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5541829	28824675	SS	2	conceived the idea and designed the experiments	conceived the idea and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5541829	28824675	TV	2	conceived the idea and designed the experiments	conceived the idea and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5541829	28824675	VR	2	performed microscopy analysis	performed microscopy analysis	Performed the experiments	Investigation	YES
5541829	28824675	WC	2	conceived the idea and designed the experiments	conceived the idea and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5541829	28824675	YZ	2	performed proteomics analysis|performed lipidomics analysis|performed microscopy analysis	performed proteomics analysis	Performed the experiments	Investigation	YES
5541829	28824675	YZ	2	performed proteomics analysis|performed lipidomics analysis|performed microscopy analysis	performed lipidomics analysis	Performed the experiments	Investigation	YES
5541829	28824675	YZ	2	performed proteomics analysis|performed lipidomics analysis|performed microscopy analysis	performed microscopy analysis	Performed the experiments	Investigation	YES
4405544	25898015	DPM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Edited the manuscript|Obtained funding for the study|Directed the interviewer team and oversaw data collection|Edited the manuscript|Interpreted the results	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405544	25898015	DPM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Edited the manuscript|Obtained funding for the study|Directed the interviewer team and oversaw data collection|Edited the manuscript|Interpreted the results	Performed the experiments	Performed the experiments	Investigation	YES
4405544	25898015	DPM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Edited the manuscript|Obtained funding for the study|Directed the interviewer team and oversaw data collection|Edited the manuscript|Interpreted the results	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405544	25898015	DPM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Edited the manuscript|Obtained funding for the study|Directed the interviewer team and oversaw data collection|Edited the manuscript|Interpreted the results	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405544	25898015	DPM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Edited the manuscript|Obtained funding for the study|Directed the interviewer team and oversaw data collection|Edited the manuscript|Interpreted the results	Edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
4405544	25898015	DPM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Edited the manuscript|Obtained funding for the study|Directed the interviewer team and oversaw data collection|Edited the manuscript|Interpreted the results	Obtained funding for the study	-	Funding acquisition	YES
4405544	25898015	DPM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Edited the manuscript|Obtained funding for the study|Directed the interviewer team and oversaw data collection|Edited the manuscript|Interpreted the results	Directed the interviewer team and oversaw data collection	Performed the experiments	Investigation|Supervision	YES
4405544	25898015	DPM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Edited the manuscript|Obtained funding for the study|Directed the interviewer team and oversaw data collection|Edited the manuscript|Interpreted the results	Edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
4405544	25898015	DPM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Edited the manuscript|Obtained funding for the study|Directed the interviewer team and oversaw data collection|Edited the manuscript|Interpreted the results	Interpreted the results	Analyzed the data	Formal analysis	YES
4405544	25898015	RK	PLoS5	Analyzed the data|Wrote the paper|Conducted the analysis|Edited the manuscript|Created tables	Analyzed the data	Analyzed the data	Formal analysis	YES
4405544	25898015	RK	PLoS5	Analyzed the data|Wrote the paper|Conducted the analysis|Edited the manuscript|Created tables	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405544	25898015	RK	PLoS5	Analyzed the data|Wrote the paper|Conducted the analysis|Edited the manuscript|Created tables	Conducted the analysis	Performed the experiments	Investigation	YES
4405544	25898015	RK	PLoS5	Analyzed the data|Wrote the paper|Conducted the analysis|Edited the manuscript|Created tables	Edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
4405544	25898015	RK	PLoS5	Analyzed the data|Wrote the paper|Conducted the analysis|Edited the manuscript|Created tables	Created tables	-	-	NO
4405544	25898015	TLO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Conceived of the research question|Drafted the survey questions|Oversaw the geocoding of the data|Constructed the life course residential histories and data linkage|Conducted the analysis|Interpreted the findings|Wrote the majority of the manuscript|Edited the manuscript|Created tables	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405544	25898015	TLO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Conceived of the research question|Drafted the survey questions|Oversaw the geocoding of the data|Constructed the life course residential histories and data linkage|Conducted the analysis|Interpreted the findings|Wrote the majority of the manuscript|Edited the manuscript|Created tables	Performed the experiments	Performed the experiments	Investigation	YES
4405544	25898015	TLO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Conceived of the research question|Drafted the survey questions|Oversaw the geocoding of the data|Constructed the life course residential histories and data linkage|Conducted the analysis|Interpreted the findings|Wrote the majority of the manuscript|Edited the manuscript|Created tables	Analyzed the data	Analyzed the data	Formal analysis	YES
4405544	25898015	TLO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Conceived of the research question|Drafted the survey questions|Oversaw the geocoding of the data|Constructed the life course residential histories and data linkage|Conducted the analysis|Interpreted the findings|Wrote the majority of the manuscript|Edited the manuscript|Created tables	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405544	25898015	TLO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Conceived of the research question|Drafted the survey questions|Oversaw the geocoding of the data|Constructed the life course residential histories and data linkage|Conducted the analysis|Interpreted the findings|Wrote the majority of the manuscript|Edited the manuscript|Created tables	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405544	25898015	TLO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Conceived of the research question|Drafted the survey questions|Oversaw the geocoding of the data|Constructed the life course residential histories and data linkage|Conducted the analysis|Interpreted the findings|Wrote the majority of the manuscript|Edited the manuscript|Created tables	Conceived of the research question	Conceived and designed the experiments	Conceptualization	YES
4405544	25898015	TLO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Conceived of the research question|Drafted the survey questions|Oversaw the geocoding of the data|Constructed the life course residential histories and data linkage|Conducted the analysis|Interpreted the findings|Wrote the majority of the manuscript|Edited the manuscript|Created tables	Drafted the survey questions	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4405544	25898015	TLO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Conceived of the research question|Drafted the survey questions|Oversaw the geocoding of the data|Constructed the life course residential histories and data linkage|Conducted the analysis|Interpreted the findings|Wrote the majority of the manuscript|Edited the manuscript|Created tables	Oversaw the geocoding of the data	-	Supervision	YES
4405544	25898015	TLO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Conceived of the research question|Drafted the survey questions|Oversaw the geocoding of the data|Constructed the life course residential histories and data linkage|Conducted the analysis|Interpreted the findings|Wrote the majority of the manuscript|Edited the manuscript|Created tables	Constructed the life course residential histories and data linkage	Performed the experiments	Investigation	YES
4405544	25898015	TLO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Conceived of the research question|Drafted the survey questions|Oversaw the geocoding of the data|Constructed the life course residential histories and data linkage|Conducted the analysis|Interpreted the findings|Wrote the majority of the manuscript|Edited the manuscript|Created tables	Conducted the analysis	Performed the experiments	Investigation	YES
4405544	25898015	TLO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Conceived of the research question|Drafted the survey questions|Oversaw the geocoding of the data|Constructed the life course residential histories and data linkage|Conducted the analysis|Interpreted the findings|Wrote the majority of the manuscript|Edited the manuscript|Created tables	Interpreted the findings	Analyzed the data	Formal analysis	YES
4405544	25898015	TLO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Conceived of the research question|Drafted the survey questions|Oversaw the geocoding of the data|Constructed the life course residential histories and data linkage|Conducted the analysis|Interpreted the findings|Wrote the majority of the manuscript|Edited the manuscript|Created tables	Wrote the majority of the manuscript	Wrote the paper	Writing - Original Draft	YES
4405544	25898015	TLO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Conceived of the research question|Drafted the survey questions|Oversaw the geocoding of the data|Constructed the life course residential histories and data linkage|Conducted the analysis|Interpreted the findings|Wrote the majority of the manuscript|Edited the manuscript|Created tables	Edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
4405544	25898015	TLO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Conceived of the research question|Drafted the survey questions|Oversaw the geocoding of the data|Constructed the life course residential histories and data linkage|Conducted the analysis|Interpreted the findings|Wrote the majority of the manuscript|Edited the manuscript|Created tables	Created tables	-	-	NO
6451290	30953533	AA	2	contributed to the design of the prospective long-term cohort|took care of the patients|provided critical feedback	contributed to the design of the prospective long-term cohort	Conceived and designed the experiments	-	YES
6451290	30953533	AA	2	contributed to the design of the prospective long-term cohort|took care of the patients|provided critical feedback	took care of the patients	Performed the experiments	Investigation	YES
6451290	30953533	AA	2	contributed to the design of the prospective long-term cohort|took care of the patients|provided critical feedback	provided critical feedback	-	-	NO
6451290	30953533	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6451290	30953533	KR	2	contributed to the design of the prospective long-term cohort|supervised the work|provided critical feedback	contributed to the design of the prospective long-term cohort	Conceived and designed the experiments	-	YES
6451290	30953533	KR	2	contributed to the design of the prospective long-term cohort|supervised the work|provided critical feedback	supervised the work	-	Supervision	YES
6451290	30953533	KR	2	contributed to the design of the prospective long-term cohort|supervised the work|provided critical feedback	provided critical feedback	-	-	NO
6451290	30953533	SG	2	took care of the patients|wrote the manuscript	took care of the patients	Performed the experiments	Investigation	YES
6451290	30953533	SG	2	took care of the patients|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6451290	30953533	SJK	2	contributed to the design of the prospective long-term cohort|analyzed and interpreted the data|provided critical feedback	contributed to the design of the prospective long-term cohort	Conceived and designed the experiments	-	YES
6451290	30953533	SJK	2	contributed to the design of the prospective long-term cohort|analyzed and interpreted the data|provided critical feedback	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
6451290	30953533	SJK	2	contributed to the design of the prospective long-term cohort|analyzed and interpreted the data|provided critical feedback	provided critical feedback	-	-	NO
6451290	30953533	TA	2	analyzed and interpreted the data|provided critical feedback	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
6451290	30953533	TA	2	analyzed and interpreted the data|provided critical feedback	provided critical feedback	-	-	NO
6451290	30953533	WMH	2	took care of the patients|provided critical feedback	took care of the patients	Performed the experiments	Investigation	YES
6451290	30953533	WMH	2	took care of the patients|provided critical feedback	provided critical feedback	-	-	NO
5299730	28178932	JM	2	analysed the bioinformatic data and participated in drafting the manuscript	analysed the bioinformatic data and participated in drafting the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5299730	28178932	PP	2	conceived the study, supervised the research and wrote the manuscript	conceived the study, supervised the research and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Supervision|Writing - Original Draft	YES
5440759	28560033	Huilin Yang	7	study design	study design	Conceived and designed the experiments	Methodology	YES
5440759	28560033	Jinlian Liu	7	data collections	data collections	Performed the experiments	Investigation	YES
5440759	28560033	Zheng Wang	7	data analysis	data analysis	Analyzed the data	Formal analysis	YES
5440759	28560033	Zhibing Tang	7	data analysis, writing	data analysis, writing	Analyzed the data|Wrote the paper	Formal analysis	YES
4486743	26161403	Marek Cybulski	2	was responsible for statistical analysis	was responsible for statistical analysis	Analyzed the data	Formal analysis	YES
6024996	29867012	A.M.	2	completed a systematic review, compiled the results, and refined the manuscript	completed a systematic review, compiled the results, and refined the manuscript	Wrote the paper	Writing - Review & Editing	YES
4833769	27083149	CC	2	completed a first draft based on a jointly developed outline	completed a first draft based on a jointly developed outline	Wrote the paper	Writing - Original Draft	YES
4833769	27083149	CM	2	edited the draft and made additions	edited the draft and made additions	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4833769	27083149	MG	2	edited the draft and made additions	edited the draft and made additions	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4833769	27083149	SS	2	edited the draft and made additions	edited the draft and made additions	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4405545	25897663	MS	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405545	25897663	MS	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405545	25897663	SM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405545	25897663	SM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405545	25897663	SM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405545	25897663	TK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the software used in analysis	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405545	25897663	TK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the software used in analysis	Performed the experiments	Performed the experiments	Investigation	YES
4405545	25897663	TK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the software used in analysis	Analyzed the data	Analyzed the data	Formal analysis	YES
4405545	25897663	TK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the software used in analysis	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405545	25897663	TK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the software used in analysis	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405545	25897663	TK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the software used in analysis	Designed the software used in analysis	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
4405545	25897663	TS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the software used in analysis	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405545	25897663	TS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the software used in analysis	Performed the experiments	Performed the experiments	Investigation	YES
4405545	25897663	TS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the software used in analysis	Analyzed the data	Analyzed the data	Formal analysis	YES
4405545	25897663	TS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the software used in analysis	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405545	25897663	TS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the software used in analysis	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405545	25897663	TS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the software used in analysis	Designed the software used in analysis	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
4405545	25897663	YA	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405545	25897663	YA	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5443924	28560034	All	2	authors 4|authors 7|authors 8	authors 4	-	-	NO
5443924	28560034	All	2	authors 4|authors 7|authors 8	authors 7	-	-	NO
5443924	28560034	All	2	authors 4|authors 7|authors 8	authors 8	-	-	NO
6025009	29757930	A.V.F.	PLoS52	performed the literature search and gathered the information|analyzed the data|wrote the paper	performed the literature search and gathered the information	Performed the experiments	Formal analysis|Investigation	YES
6025009	29757930	A.V.F.	PLoS52	performed the literature search and gathered the information|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
6025009	29757930	A.V.F.	PLoS52	performed the literature search and gathered the information|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6025009	29757930	K.C.N.V.	PLoS52	conceived and designed the project|analyzed the data|wrote the paper	conceived and designed the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
6025009	29757930	K.C.N.V.	PLoS52	conceived and designed the project|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
6025009	29757930	K.C.N.V.	PLoS52	conceived and designed the project|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6025009	29757930	M.D.P.	PLoS52	performed the literature search and gathered the information	performed the literature search and gathered the information	Performed the experiments	Formal analysis|Investigation	YES
4834365	27086838	All authors	2	reviewed and approved the final version	reviewed and approved the final version	-	-	NO
4834365	27086838	FM	2	had responsibility for conceptualizing and writing the paper|conducted the analyses for the paper	had responsibility for conceptualizing and writing the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4834365	27086838	FM	2	had responsibility for conceptualizing and writing the paper|conducted the analyses for the paper	conducted the analyses for the paper	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4834365	27086838	LC	2	had responsibility for the overall study design and management|had responsibility for conceptualizing and writing the paper|conducted the analyses for the paper	had responsibility for the overall study design and management	Conceived and designed the experiments	Methodology	YES
4834365	27086838	LC	2	had responsibility for the overall study design and management|had responsibility for conceptualizing and writing the paper|conducted the analyses for the paper	had responsibility for conceptualizing and writing the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4834365	27086838	LC	2	had responsibility for the overall study design and management|had responsibility for conceptualizing and writing the paper|conducted the analyses for the paper	conducted the analyses for the paper	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4834365	27086838	LS	2	had responsibility for conceptualizing and writing the paper	had responsibility for conceptualizing and writing the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4834365	27086838	Lucie Cluver	2	has full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis	has full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis	Analyzed the data	Data curation|Formal analysis	YES
4834365	27086838	MB	2	had responsibility for the overall study design and management|had responsibility for conceptualizing and writing the paper	had responsibility for the overall study design and management	Conceived and designed the experiments	Methodology	YES
4834365	27086838	MB	2	had responsibility for the overall study design and management|had responsibility for conceptualizing and writing the paper	had responsibility for conceptualizing and writing the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4834365	27086838	MO	2	had responsibility for the overall study design and management|had responsibility for conceptualizing and writing the paper|conducted the analyses for the paper	had responsibility for the overall study design and management	Conceived and designed the experiments	Methodology	YES
4834365	27086838	MO	2	had responsibility for the overall study design and management|had responsibility for conceptualizing and writing the paper|conducted the analyses for the paper	had responsibility for conceptualizing and writing the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4834365	27086838	MO	2	had responsibility for the overall study design and management|had responsibility for conceptualizing and writing the paper|conducted the analyses for the paper	conducted the analyses for the paper	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6456950	30967145	EW	CRediT	Conceptualization|Methodology|Writing - review & editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6456950	30967145	EW	CRediT	Conceptualization|Methodology|Writing - review & editing	Methodology	Performed the experiments	Methodology	YES
6456950	30967145	EW	CRediT	Conceptualization|Methodology|Writing - review & editing	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
6456950	30967145	HS	CRediT	Conceptualization|Data curation|Formal analysis|Methodology|Supervision|Validation|Writing - review & editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6456950	30967145	HS	CRediT	Conceptualization|Data curation|Formal analysis|Methodology|Supervision|Validation|Writing - review & editing	Data curation	Analyzed the data	Data curation	YES
6456950	30967145	HS	CRediT	Conceptualization|Data curation|Formal analysis|Methodology|Supervision|Validation|Writing - review & editing	Formal analysis	Analyzed the data	Formal analysis	YES
6456950	30967145	HS	CRediT	Conceptualization|Data curation|Formal analysis|Methodology|Supervision|Validation|Writing - review & editing	Methodology	Performed the experiments	Methodology	YES
6456950	30967145	HS	CRediT	Conceptualization|Data curation|Formal analysis|Methodology|Supervision|Validation|Writing - review & editing	Supervision	-	Supervision	YES
6456950	30967145	HS	CRediT	Conceptualization|Data curation|Formal analysis|Methodology|Supervision|Validation|Writing - review & editing	Validation	Performed the experiments	Validation	YES
6456950	30967145	HS	CRediT	Conceptualization|Data curation|Formal analysis|Methodology|Supervision|Validation|Writing - review & editing	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
6456950	30967145	JR	CRediT	Conceptualization|Data curation|Formal analysis|Funding acquisition|Methodology|Project administration|Validation|Writing-original draft|Writing - review & editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6456950	30967145	JR	CRediT	Conceptualization|Data curation|Formal analysis|Funding acquisition|Methodology|Project administration|Validation|Writing-original draft|Writing - review & editing	Data curation	Analyzed the data	Data curation	YES
6456950	30967145	JR	CRediT	Conceptualization|Data curation|Formal analysis|Funding acquisition|Methodology|Project administration|Validation|Writing-original draft|Writing - review & editing	Formal analysis	Analyzed the data	Formal analysis	YES
6456950	30967145	JR	CRediT	Conceptualization|Data curation|Formal analysis|Funding acquisition|Methodology|Project administration|Validation|Writing-original draft|Writing - review & editing	Funding acquisition	-	Funding acquisition	YES
6456950	30967145	JR	CRediT	Conceptualization|Data curation|Formal analysis|Funding acquisition|Methodology|Project administration|Validation|Writing-original draft|Writing - review & editing	Methodology	Performed the experiments	Methodology	YES
6456950	30967145	JR	CRediT	Conceptualization|Data curation|Formal analysis|Funding acquisition|Methodology|Project administration|Validation|Writing-original draft|Writing - review & editing	Project administration	-	Project administration	YES
6456950	30967145	JR	CRediT	Conceptualization|Data curation|Formal analysis|Funding acquisition|Methodology|Project administration|Validation|Writing-original draft|Writing - review & editing	Validation	Performed the experiments	Validation	YES
6456950	30967145	JR	CRediT	Conceptualization|Data curation|Formal analysis|Funding acquisition|Methodology|Project administration|Validation|Writing-original draft|Writing - review & editing	Writing-original draft	Wrote the paper	Writing - Original Draft	YES
6456950	30967145	JR	CRediT	Conceptualization|Data curation|Formal analysis|Funding acquisition|Methodology|Project administration|Validation|Writing-original draft|Writing - review & editing	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
6456950	30967145	SK	CRediT	Conceptualization|Data curation|Formal analysis|Methodology|Supervision|Validation|Writing - review & editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6456950	30967145	SK	CRediT	Conceptualization|Data curation|Formal analysis|Methodology|Supervision|Validation|Writing - review & editing	Data curation	Analyzed the data	Data curation	YES
6456950	30967145	SK	CRediT	Conceptualization|Data curation|Formal analysis|Methodology|Supervision|Validation|Writing - review & editing	Formal analysis	Analyzed the data	Formal analysis	YES
6456950	30967145	SK	CRediT	Conceptualization|Data curation|Formal analysis|Methodology|Supervision|Validation|Writing - review & editing	Methodology	Performed the experiments	Methodology	YES
6456950	30967145	SK	CRediT	Conceptualization|Data curation|Formal analysis|Methodology|Supervision|Validation|Writing - review & editing	Supervision	-	Supervision	YES
6456950	30967145	SK	CRediT	Conceptualization|Data curation|Formal analysis|Methodology|Supervision|Validation|Writing - review & editing	Validation	Performed the experiments	Validation	YES
6456950	30967145	SK	CRediT	Conceptualization|Data curation|Formal analysis|Methodology|Supervision|Validation|Writing - review & editing	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
5299747	28178945	CEA	2	designed the research|collected data|conducted the experiments|analyzed and interpreted results|wrote the manuscript|commented, edited and revised the final manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
5299747	28178945	CEA	2	designed the research|collected data|conducted the experiments|analyzed and interpreted results|wrote the manuscript|commented, edited and revised the final manuscript	collected data	Performed the experiments	Investigation	YES
5299747	28178945	CEA	2	designed the research|collected data|conducted the experiments|analyzed and interpreted results|wrote the manuscript|commented, edited and revised the final manuscript	conducted the experiments	Performed the experiments	Investigation	YES
5299747	28178945	CEA	2	designed the research|collected data|conducted the experiments|analyzed and interpreted results|wrote the manuscript|commented, edited and revised the final manuscript	analyzed and interpreted results	Analyzed the data	Formal analysis	YES
5299747	28178945	CEA	2	designed the research|collected data|conducted the experiments|analyzed and interpreted results|wrote the manuscript|commented, edited and revised the final manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5299747	28178945	CEA	2	designed the research|collected data|conducted the experiments|analyzed and interpreted results|wrote the manuscript|commented, edited and revised the final manuscript	commented, edited and revised the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5299747	28178945	CGC	2	designed the research|analyzed and interpreted results|commented, edited and revised the final manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
5299747	28178945	CGC	2	designed the research|analyzed and interpreted results|commented, edited and revised the final manuscript	analyzed and interpreted results	Analyzed the data	Formal analysis	YES
5299747	28178945	CGC	2	designed the research|analyzed and interpreted results|commented, edited and revised the final manuscript	commented, edited and revised the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5299747	28178945	EEP	2	commented, edited and revised the final manuscript	commented, edited and revised the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5299747	28178945	EMF	2	collected data|conducted the experiments|commented, edited and revised the final manuscript	collected data	Performed the experiments	Investigation	YES
5299747	28178945	EMF	2	collected data|conducted the experiments|commented, edited and revised the final manuscript	conducted the experiments	Performed the experiments	Investigation	YES
5299747	28178945	EMF	2	collected data|conducted the experiments|commented, edited and revised the final manuscript	commented, edited and revised the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5299747	28178945	IZ	2	analyzed and interpreted results	analyzed and interpreted results	Analyzed the data	Formal analysis	YES
5299747	28178945	JLR	2	collected data|conducted the experiments|analyzed and interpreted results|wrote the manuscript|commented, edited and revised the final manuscript	collected data	Performed the experiments	Investigation	YES
5299747	28178945	JLR	2	collected data|conducted the experiments|analyzed and interpreted results|wrote the manuscript|commented, edited and revised the final manuscript	conducted the experiments	Performed the experiments	Investigation	YES
5299747	28178945	JLR	2	collected data|conducted the experiments|analyzed and interpreted results|wrote the manuscript|commented, edited and revised the final manuscript	analyzed and interpreted results	Analyzed the data	Formal analysis	YES
5299747	28178945	JLR	2	collected data|conducted the experiments|analyzed and interpreted results|wrote the manuscript|commented, edited and revised the final manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5299747	28178945	JLR	2	collected data|conducted the experiments|analyzed and interpreted results|wrote the manuscript|commented, edited and revised the final manuscript	commented, edited and revised the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5299747	28178945	SZL	2	designed the research|collected data|conducted the experiments|analyzed and interpreted results|wrote the manuscript|commented, edited and revised the final manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
5299747	28178945	SZL	2	designed the research|collected data|conducted the experiments|analyzed and interpreted results|wrote the manuscript|commented, edited and revised the final manuscript	collected data	Performed the experiments	Investigation	YES
5299747	28178945	SZL	2	designed the research|collected data|conducted the experiments|analyzed and interpreted results|wrote the manuscript|commented, edited and revised the final manuscript	conducted the experiments	Performed the experiments	Investigation	YES
5299747	28178945	SZL	2	designed the research|collected data|conducted the experiments|analyzed and interpreted results|wrote the manuscript|commented, edited and revised the final manuscript	analyzed and interpreted results	Analyzed the data	Formal analysis	YES
5299747	28178945	SZL	2	designed the research|collected data|conducted the experiments|analyzed and interpreted results|wrote the manuscript|commented, edited and revised the final manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5299747	28178945	SZL	2	designed the research|collected data|conducted the experiments|analyzed and interpreted results|wrote the manuscript|commented, edited and revised the final manuscript	commented, edited and revised the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5451184	28603611	AAW	2	have contributed the management of the patient	have contributed the management of the patient	Performed the experiments	Investigation	YES
5451184	28603611	EAGK	2	have contributed to writing, revising and editing of the manuscript	have contributed to writing, revising and editing of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5451184	28603611	HS	2	have contributed the management of the patient	have contributed the management of the patient	Performed the experiments	Investigation	YES
5451184	28603611	KAE	2	have contributed the management of the patient|have contributed to writing, revising and editing of the manuscript	have contributed the management of the patient	Performed the experiments	Investigation	YES
5451184	28603611	KAE	2	have contributed the management of the patient|have contributed to writing, revising and editing of the manuscript	have contributed to writing, revising and editing of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5451184	28603611	MS	2	have contributed the management of the patient	have contributed the management of the patient	Performed the experiments	Investigation	YES
5451184	28603611	WE	2	have contributed the management of the patient|have contributed to writing, revising and editing of the manuscript	have contributed the management of the patient	Performed the experiments	Investigation	YES
5451184	28603611	WE	2	have contributed the management of the patient|have contributed to writing, revising and editing of the manuscript	have contributed to writing, revising and editing of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3978377	24599513	BG	7	Idea, planning, data programming, interpretation of results, manuscript writing	Idea, planning, data programming, interpretation of results, manuscript writing	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Methodology|Software|Writing - Original Draft	YES
3978377	24599513	BZ	7	Co-planning, interpretation of results, scientific revision of manuscript	Co-planning, interpretation of results, scientific revision of manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
3978377	24599513	HG	7	Data programming, statistical expertise and interpretation, scientific revision of manuscript	Data programming, statistical expertise and interpretation, scientific revision of manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Software|Writing - Review & Editing	YES
3978377	24599513	LH	7	Interpretation of results, scientific revision of manuscript	Interpretation of results, scientific revision of manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
6025072	29751528	I.B.	2	conceived the project, designed and developed the computer simulation, and was chief supervisor of the project	conceived the project, designed and developed the computer simulation, and was chief supervisor of the project	Conceived and designed the experiments	Conceptualization|Formal analysis|Methodology|Supervision	YES
6025072	29751528	K.L.	2	performed the subsequent qualitative analysis and helped write the manuscript	performed the subsequent qualitative analysis and helped write the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6025072	29751528	T.L.	2	helped develop the computer simulation	helped develop the computer simulation	-	Formal analysis	YES
6025072	29751528	UON	2	providing guidance on the design and ethical considerations	providing guidance on the design and ethical considerations	Conceived and designed the experiments	Supervision	YES
5299762	28178941	IKJ	2	conceived of and designed the study|wrote the final manuscript	conceived of and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5299762	28178941	IKJ	2	conceived of and designed the study|wrote the final manuscript	wrote the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5299762	28178941	LR	2	conceived of and designed the study|performed all the analyses|wrote the final manuscript	conceived of and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5299762	28178941	LR	2	conceived of and designed the study|performed all the analyses|wrote the final manuscript	performed all the analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5299762	28178941	LR	2	conceived of and designed the study|performed all the analyses|wrote the final manuscript	wrote the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5543080	28824685	BT	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5543080	28824685	JZ	PLoS52	gave advice and guidance for the experiment	gave advice and guidance for the experiment	-	Supervision	YES
5543080	28824685	KZ	PLoS52	gave advice and guidance for the experiment	gave advice and guidance for the experiment	-	Supervision	YES
5543080	28824685	PL	PLoS52	provided the idea, supervised the research work	provided the idea, supervised the research work	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Supervision	YES
5543080	28824685	QW	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5543080	28824685	ZH	PLoS52	designed the experiments, analyzed the results, and wrote the manuscript	designed the experiments, analyzed the results, and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3481075	22695953	N. Fotiadis	1	Guarantor of integrity of the entire study	Guarantor of integrity of the entire study	-	-	NO
6463654	30987670	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6463654	30987670	CSW	2	had assisted in the revision of the manuscript	had assisted in the revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
6463654	30987670	LGC	2	is the primary investigator of the project and oversaw the designing of the study to the writing of manuscript	is the primary investigator of the project and oversaw the designing of the study to the writing of manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Original Draft	YES
6463654	30987670	MJH	2	was involved in the designing and acquisition of cognitive testing data	was involved in the designing and acquisition of cognitive testing data	Conceived and designed the experiments|Performed the experiments	Investigation	YES
6463654	30987670	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
6463654	30987670	YCL	2	was involved in the administration of cognitive testing as well as necessary data entry	was involved in the administration of cognitive testing as well as necessary data entry	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
6463654	30987670	YO	2	performed and interpreted the relevant data analysis and was a major contributor in writing the manuscript	performed and interpreted the relevant data analysis and was a major contributor in writing the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4837333	27094914	All other authors	2	made significant intellectual contributions, reviewed the final draft and approved the manuscript	made significant intellectual contributions, reviewed the final draft and approved the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4837333	27094914	EW	2	also designed the original access study and secured funding	also designed the original access study and secured funding	Conceived and designed the experiments	Funding acquisition|Methodology	YES
4837333	27094914	M-JM	2	conceptualized the current study, conducted the statistical analyses, wrote all drafts and incorporated all revisions	conceptualized the current study, conducted the statistical analyses, wrote all drafts and incorporated all revisions	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
4837333	27094914	TK	2	also designed the original access study and secured funding	also designed the original access study and secured funding	Conceived and designed the experiments	Funding acquisition|Methodology	YES
4405546	25898365	A. Sarr	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405546	25898365	A. Sarr	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405546	25898365	A. Sarr	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405546	25898365	A. Soko	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4405546	25898365	A. Soko	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4405546	25898365	AKB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405546	25898365	AKB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405546	25898365	AKB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405546	25898365	DK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405546	25898365	DK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405546	25898365	DK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405546	25898365	FC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405546	25898365	FC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405546	25898365	FC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405546	25898365	IH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405546	25898365	IH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405546	25898365	IH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405546	25898365	MCH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405546	25898365	MCH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405546	25898365	MCH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405546	25898365	MM	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4405546	25898365	MM	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4405546	25898365	MW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405546	25898365	MW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405546	25898365	MW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405546	25898365	R. Mataya	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405546	25898365	R. Mataya	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405546	25898365	R. Mataya	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405546	25898365	R. Mwenda	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405546	25898365	R. Mwenda	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405546	25898365	SBW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405546	25898365	SBW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405546	25898365	SBW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405546	25898365	SER	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405546	25898365	SER	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405546	25898365	SER	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405546	25898365	SER	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405546	25898365	SG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405546	25898365	SG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405546	25898365	SG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405546	25898365	SK	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405546	25898365	WCM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405546	25898365	WCM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405546	25898365	WCM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5451188	28603610	CD	2	was involved in study concept, design, analysis and write up the manuscript	was involved in study concept, design, analysis and write up the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
5451188	28603610	GG	2	was the senior surgeon performing all surgical procedures as well as being involved in the study concept and design	was the senior surgeon performing all surgical procedures as well as being involved in the study concept and design	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
5451188	28603610	R Shah	2	was involved in study concept, design, data collection, analysis and write up of the manuscript	was involved in study concept, design, data collection, analysis and write up of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5451188	28603610	R Singh	2	was involved in data collection, analysis and operative assistant	was involved in data collection, analysis and operative assistant	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4841152	27105305	CC	2	wrote the first draft	wrote the first draft	Wrote the paper	Writing - Original Draft	YES
4841152	27105305	DW	2	conducted the modelling, edited the manuscript and oversaw its development	conducted the modelling, edited the manuscript and oversaw its development	Performed the experiments|Wrote the paper	Investigation|Methodology|Supervision|Writing - Review & Editing	YES
4841152	27105305	RL	2	wrote the first draft	wrote the first draft	Wrote the paper	Writing - Original Draft	YES
5543098	28824694	AAC	7	set up trials, carried out disease assessments, molecular work including qpcr troubleshooting, editorial input into manuscript	set up trials, carried out disease assessments, molecular work including qpcr troubleshooting, editorial input into manuscript	Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
5543098	28824694	AH	7	carried out all molecular work and analysis including qpcr troubleshooting, editorial input into manuscript	carried out all molecular work and analysis including qpcr troubleshooting, editorial input into manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5543098	28824694	DJ	7	carried out all chemical protocols including trouble shooting, editorial input into manuscript	carried out all chemical protocols including trouble shooting, editorial input into manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
5543098	28824694	JB	7	developed and modified protocols for successful rna extraction thus overcoming a key technical hurdle, editorial input into manuscript	developed and modified protocols for successful rna extraction thus overcoming a key technical hurdle, editorial input into manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5543098	28824694	JC	7	developed phytohormone protocols and carried out all chemical work, editorial input into manuscript	developed phytohormone protocols and carried out all chemical work, editorial input into manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5543098	28824694	JP	7	molecular work including qpcr system optimisation, editorial input into manuscript	molecular work including qpcr system optimisation, editorial input into manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5543098	28824694	JT	7	set up trials, carried out disease assessments, data analysis, editorial input into manuscript	set up trials, carried out disease assessments, data analysis, editorial input into manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Review & Editing	YES
5543098	28824694	KW	7	designed experiments, set up trials, carried out all molecular work, including primer design and developing qpcr protocols, data analysis, wrote the manuscript	designed experiments, set up trials, carried out all molecular work, including primer design and developing qpcr protocols, data analysis, wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5543098	28824694	MW	7	statistical analysis and editorial input	statistical analysis and editorial input	Analyzed the data	Formal analysis	YES
5543098	28824694	TR	7	experimental design, input into chemical protocols, identification of most suitable phytohormone markers, data interpretation, major editorial input	experimental design, input into chemical protocols, identification of most suitable phytohormone markers, data interpretation, major editorial input	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5454084	28603612	D.K.	1	Drafting the article	Drafting the article	Wrote the paper	Writing - Original Draft	YES
5454084	28603612	D.S.	1	Acquisition of data	Acquisition of data	Performed the experiments	Investigation	YES
5454084	28603612	G.G.	1	Drafting the article	Drafting the article	Wrote the paper	Writing - Original Draft	YES
5454084	28603612	G.P.	1	Conception and design of the study	Conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5454084	28603612	M.F.	1	Conception and design of the study	Conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405566	25898393	CM	PLoS5	Analyzed the data|Field survey	Analyzed the data	Analyzed the data	Formal analysis	YES
4405566	25898393	CM	PLoS5	Analyzed the data|Field survey	Field survey	Performed the experiments	Investigation	YES
4405566	25898393	DA	PLoS5	Field survey	Field survey	Performed the experiments	Investigation	YES
4405566	25898393	H. Sudo	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405566	25898393	H. Sukchai	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4405566	25898393	IT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Field survey	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405566	25898393	IT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Field survey	Performed the experiments	Performed the experiments	Investigation	YES
4405566	25898393	IT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Field survey	Analyzed the data	Analyzed the data	Formal analysis	YES
4405566	25898393	IT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Field survey	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405566	25898393	IT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Field survey	Field survey	Performed the experiments	Investigation	YES
4405566	25898393	IY	PLoS5	Analyzed the data|Field survey	Analyzed the data	Analyzed the data	Formal analysis	YES
4405566	25898393	IY	PLoS5	Analyzed the data|Field survey	Field survey	Performed the experiments	Investigation	YES
4405566	25898393	JS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Field survey	Analyzed the data	Analyzed the data	Formal analysis	YES
4405566	25898393	JS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Field survey	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405566	25898393	JS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Field survey	Field survey	Performed the experiments	Investigation	YES
4405566	25898393	KH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405566	25898393	KH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405566	25898393	KH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405566	25898393	KH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405566	25898393	MG	PLoS5	Experimental coordination	Experimental coordination	-	Project administration	YES
4405566	25898393	PP	PLoS5	Analyzed the data|Field survey	Analyzed the data	Analyzed the data	Formal analysis	YES
4405566	25898393	PP	PLoS5	Analyzed the data|Field survey	Field survey	Performed the experiments	Investigation	YES
4405566	25898393	SK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Field survey	Analyzed the data	Analyzed the data	Formal analysis	YES
4405566	25898393	SK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Field survey	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405566	25898393	SK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Field survey	Field survey	Performed the experiments	Investigation	YES
4405566	25898393	TM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405566	25898393	TM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405566	25898393	TM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5301324	28183283	CDH	PLoS52	critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5301324	28183283	CHN	PLoS52	performed the experiments|contributed reagents/materials/analysis tools|analyzed the data and wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5301324	28183283	CHN	PLoS52	performed the experiments|contributed reagents/materials/analysis tools|analyzed the data and wrote the paper	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5301324	28183283	CHN	PLoS52	performed the experiments|contributed reagents/materials/analysis tools|analyzed the data and wrote the paper	analyzed the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5301324	28183283	SMW	PLoS52	performed the experiments|contributed reagents/materials/analysis tools	performed the experiments	Performed the experiments	Investigation	YES
5301324	28183283	SMW	PLoS52	performed the experiments|contributed reagents/materials/analysis tools	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5301324	28183283	TTo	PLoS52	contributed reagents/materials/analysis tools	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5301324	28183283	TTr	PLoS52	contributed reagents/materials/analysis tools	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5301324	28183283	WMW	PLoS52	contributed reagents/materials/analysis tools|critically revised the manuscript	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5301324	28183283	WMW	PLoS52	contributed reagents/materials/analysis tools|critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5301324	28183283	ZXG	PLoS52	conceived and designed the experiments|analyzed the data and wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5301324	28183283	ZXG	PLoS52	conceived and designed the experiments|analyzed the data and wrote the paper	analyzed the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3065731	21490907	All	2	were involved in critical revision of the paper and approved the final version	were involved in critical revision of the paper and approved the final version	Wrote the paper	Writing - Review & Editing	YES
3065731	21490907	E. Ikoona	2	were involved in protocol development, study facilitation and reviewing the paper	were involved in protocol development, study facilitation and reviewing the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft|Writing - Review & Editing	YES
3065731	21490907	E. Katabira	2	were the principal investigators, wrote the protocol, were involved in study design, supervised implementation of the study, and reviewed the paper	were the principal investigators, wrote the protocol, were involved in study design, supervised implementation of the study, and reviewed the paper	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Funding acquisition|Investigation|Methodology|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
3065731	21490907	E. Namagala	2	were involved in protocol development, study facilitation and reviewing the paper	were involved in protocol development, study facilitation and reviewing the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft|Writing - Review & Editing	YES
3065731	21490907	H. Balidawa	2	were involved in protocol development, study facilitation and reviewing the paper	were involved in protocol development, study facilitation and reviewing the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft|Writing - Review & Editing	YES
3065731	21490907	J. Walley	2	were the principal investigators, wrote the protocol, were involved in study design, supervised implementation of the study, and reviewed the paper	were the principal investigators, wrote the protocol, were involved in study design, supervised implementation of the study, and reviewed the paper	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Funding acquisition|Investigation|Methodology|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
3065731	21490907	S. Kunutsor	2	were involved in implementation of the study, coordination of field activities and data collection|was involved in design of study, devised data collection tools, inputted data, did the data analysis and interpretation and wrote the first draft	were involved in implementation of the study, coordination of field activities and data collection	Performed the experiments	Investigation|Project administration	YES
3065731	21490907	S. Kunutsor	2	were involved in implementation of the study, coordination of field activities and data collection|was involved in design of study, devised data collection tools, inputted data, did the data analysis and interpretation and wrote the first draft	was involved in design of study, devised data collection tools, inputted data, did the data analysis and interpretation and wrote the first draft	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
3065731	21490907	S. Muchuro	2	were involved in implementation of the study, coordination of field activities and data collection	were involved in implementation of the study, coordination of field activities and data collection	Performed the experiments	Investigation|Project administration	YES
3978378	24493365	All authors	2	were involved in the study conception and design	were involved in the study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
3978378	24493365	CC	2	completed the statistical analysis	completed the statistical analysis	Analyzed the data	Formal analysis	YES
3978378	24493365	CH	2	provided methodological and content expertise during the manuscript preparation and critically revised the draft manuscript	provided methodological and content expertise during the manuscript preparation and critically revised the draft manuscript	Performed the experiments|Wrote the paper	Methodology|Writing - Original Draft|Writing - Review & Editing	YES
3978378	24493365	FM	2	completed the statistical analysis	completed the statistical analysis	Analyzed the data	Formal analysis	YES
3978378	24493365	GC	2	interpreted the data and drafted the paper	interpreted the data and drafted the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3978378	24493365	KB	2	provided methodological and content expertise during the manuscript preparation and critically revised the draft manuscript	provided methodological and content expertise during the manuscript preparation and critically revised the draft manuscript	Performed the experiments|Wrote the paper	Methodology|Writing - Original Draft|Writing - Review & Editing	YES
3978378	24493365	MB	2	interpreted the data and drafted the paper	interpreted the data and drafted the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3978378	24493365	NM	2	completed the statistical analysis	completed the statistical analysis	Analyzed the data	Formal analysis	YES
3978378	24493365	RG	2	interpreted the data and drafted the paper	interpreted the data and drafted the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3978378	24493365	RK	2	provided methodological and content expertise during the manuscript preparation and critically revised the draft manuscript	provided methodological and content expertise during the manuscript preparation and critically revised the draft manuscript	Performed the experiments|Wrote the paper	Methodology|Writing - Original Draft|Writing - Review & Editing	YES
3978378	24493365	SS	2	provided methodological and content expertise during the manuscript preparation and critically revised the draft manuscript	provided methodological and content expertise during the manuscript preparation and critically revised the draft manuscript	Performed the experiments|Wrote the paper	Methodology|Writing - Original Draft|Writing - Review & Editing	YES
3978378	24493365	TF	2	provided methodological and content expertise during the manuscript preparation and critically revised the draft manuscript	provided methodological and content expertise during the manuscript preparation and critically revised the draft manuscript	Performed the experiments|Wrote the paper	Methodology|Writing - Original Draft|Writing - Review & Editing	YES
4845592	27113335	All authors	2	were responsible for, reviewed and approved the final manuscript	were responsible for, reviewed and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4845592	27113335	BE	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
4845592	27113335	DN	2	designed the study|analyzed the data and drafted the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
4845592	27113335	DN	2	designed the study|analyzed the data and drafted the manuscript	analyzed the data and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4845592	27113335	ML	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
4845592	27113335	MY	2	coordinated the study	coordinated the study	-	Project administration	YES
4845592	27113335	OT	2	analyzed the data and drafted the manuscript	analyzed the data and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4845592	27113335	RR	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
4845592	27113335	SD	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
4845592	27113335	SGK	2	designed the study|coordinated the study	designed the study	Conceived and designed the experiments	Methodology	YES
4845592	27113335	SGK	2	designed the study|coordinated the study	coordinated the study	-	Project administration	YES
4845592	27113335	SH	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
4845592	27113335	TG	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
4845592	27113335	WE	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
4845592	27113335	ZM	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5543178	28824689	AOV	2	conducted field experiments, laboratory measurements, and statistics and initial writing	conducted field experiments, laboratory measurements, and statistics and initial writing	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation	YES
5543178	28824689	TF	2	provided the purdue isotope lab resources and technical assistance with the data output from the mass spectrometer analyses of isotopic plant tissue samples	provided the purdue isotope lab resources and technical assistance with the data output from the mass spectrometer analyses of isotopic plant tissue samples	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
6025090	29587353	Amy N. Thompson	2	conceived and designed the research for this manuscript|performed the data analysis for the study|provided final editing and all required edits based on reviewer comments for publication	conceived and designed the research for this manuscript	Conceived and designed the experiments	Conceptualization|Methodology	YES
6025090	29587353	Amy N. Thompson	2	conceived and designed the research for this manuscript|performed the data analysis for the study|provided final editing and all required edits based on reviewer comments for publication	performed the data analysis for the study	Analyzed the data	Formal analysis	YES
6025090	29587353	Amy N. Thompson	2	conceived and designed the research for this manuscript|performed the data analysis for the study|provided final editing and all required edits based on reviewer comments for publication	provided final editing and all required edits based on reviewer comments for publication	Wrote the paper	Writing - Review & Editing	YES
6025090	29587353	Kathryn M. Holt	2	conceived and designed the research for this manuscript|performed the data analysis for the study|wrote the manuscript	conceived and designed the research for this manuscript	Conceived and designed the experiments	Conceptualization|Methodology	YES
6025090	29587353	Kathryn M. Holt	2	conceived and designed the research for this manuscript|performed the data analysis for the study|wrote the manuscript	performed the data analysis for the study	Analyzed the data	Formal analysis	YES
6025090	29587353	Kathryn M. Holt	2	conceived and designed the research for this manuscript|performed the data analysis for the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4405567	25897843	BS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405567	25897843	BS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405567	25897843	BS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405567	25897843	BS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405567	25897843	BS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405567	25897843	DS	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405567	25897843	DS	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405567	25897843	EL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405567	25897843	EL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405567	25897843	EL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405567	25897843	IC	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405567	25897843	IC	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405567	25897843	JCL	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405567	25897843	JCL	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405567	25897843	KGG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405567	25897843	KGG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405567	25897843	KGG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405567	25897843	KGG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405567	25897843	LZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405567	25897843	LZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405567	25897843	LZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405567	25897843	NR	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405567	25897843	NR	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405567	25897843	TS	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405567	25897843	TS	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405567	25897843	UH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405567	25897843	UH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405567	25897843	UH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405567	25897843	WS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405567	25897843	WS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405567	25897843	WS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405567	25897843	WS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405567	25897843	WS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5460737	28626580	Both authors	2	equally helped in collecting data and gathering information about the study	equally helped in collecting data and gathering information about the study	Performed the experiments	Investigation	YES
5301350	28183269	AE	2	contributed intellectually and critically to the manuscript	contributed intellectually and critically to the manuscript	-	-	NO
5301350	28183269	FJ	2	designed the project and revised the manuscript	designed the project and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5301350	28183269	HT	2	provided the plants and contributed to the sample collection	provided the plants and contributed to the sample collection	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5301350	28183269	LH	2	designed and performed the experiment, and drafted the manuscript	designed and performed the experiment, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
4025175	24658827	Anders Asberg	1	Designed research	Designed research	Conceived and designed the experiments	Methodology	YES
4025175	24658827	Beata Mohebi	1	Performed research|Analyzed data	Performed research	Performed the experiments	Investigation	YES
4025175	24658827	Beata Mohebi	1	Performed research|Analyzed data	Analyzed data	Analyzed the data	Formal analysis	YES
4025175	24658827	Hege Christensen	1	Wrote manuscript|Designed research|Performed research|Analyzed data	Wrote manuscript	Wrote the paper	Writing - Original Draft	YES
4025175	24658827	Hege Christensen	1	Wrote manuscript|Designed research|Performed research|Analyzed data	Designed research	Conceived and designed the experiments	Methodology	YES
4025175	24658827	Hege Christensen	1	Wrote manuscript|Designed research|Performed research|Analyzed data	Performed research	Performed the experiments	Investigation	YES
4025175	24658827	Hege Christensen	1	Wrote manuscript|Designed research|Performed research|Analyzed data	Analyzed data	Analyzed the data	Formal analysis	YES
4025175	24658827	Ingrid Lunde	1	Wrote manuscript|Designed research|Performed research|Analyzed data	Wrote manuscript	Wrote the paper	Writing - Original Draft	YES
4025175	24658827	Ingrid Lunde	1	Wrote manuscript|Designed research|Performed research|Analyzed data	Designed research	Conceived and designed the experiments	Methodology	YES
4025175	24658827	Ingrid Lunde	1	Wrote manuscript|Designed research|Performed research|Analyzed data	Performed research	Performed the experiments	Investigation	YES
4025175	24658827	Ingrid Lunde	1	Wrote manuscript|Designed research|Performed research|Analyzed data	Analyzed data	Analyzed the data	Formal analysis	YES
4025175	24658827	Karsten Midtvedt	1	Wrote manuscript|Designed research	Wrote manuscript	Wrote the paper	Writing - Original Draft	YES
4025175	24658827	Karsten Midtvedt	1	Wrote manuscript|Designed research	Designed research	Conceived and designed the experiments	Methodology	YES
4025175	24658827	Miriam Dahl	1	Performed research|Analyzed data	Performed research	Performed the experiments	Investigation	YES
4025175	24658827	Miriam Dahl	1	Performed research|Analyzed data	Analyzed data	Analyzed the data	Formal analysis	YES
4025175	24658827	Sara Bremer	1	Wrote manuscript|Designed research|Performed research|Analyzed data	Wrote manuscript	Wrote the paper	Writing - Original Draft	YES
4025175	24658827	Sara Bremer	1	Wrote manuscript|Designed research|Performed research|Analyzed data	Designed research	Conceived and designed the experiments	Methodology	YES
4025175	24658827	Sara Bremer	1	Wrote manuscript|Designed research|Performed research|Analyzed data	Performed research	Performed the experiments	Investigation	YES
4025175	24658827	Sara Bremer	1	Wrote manuscript|Designed research|Performed research|Analyzed data	Analyzed data	Analyzed the data	Formal analysis	YES
4025175	24658827	Stein Bergan	1	Wrote manuscript|Designed research|Analyzed data	Wrote manuscript	Wrote the paper	Writing - Original Draft	YES
4025175	24658827	Stein Bergan	1	Wrote manuscript|Designed research|Analyzed data	Designed research	Conceived and designed the experiments	Methodology	YES
4025175	24658827	Stein Bergan	1	Wrote manuscript|Designed research|Analyzed data	Analyzed data	Analyzed the data	Formal analysis	YES
3603435	23533358	Xiaobo Guo	2	contributed equally	contributed equally	-	-	NO
3603435	23533358	Zhifa Liu	2	contributed equally	contributed equally	-	-	NO
4846797	27118443	All authors	2	read, provided input to, and approved the final manuscript	read, provided input to, and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4846797	27118443	EKN	2	conceived of the review question and methodology	conceived of the review question and methodology	Conceived and designed the experiments|Performed the experiments	Conceptualization|Methodology	YES
4846797	27118443	HMNY	2	conducted the database searches	conducted the database searches	Contributed reagents/materials/analysis tools	Software	YES
4846797	27118443	MV	2	conducted the database searches	conducted the database searches	Contributed reagents/materials/analysis tools	Software	YES
4846797	27118443	OO	2	conducted the database searches	conducted the database searches	Contributed reagents/materials/analysis tools	Software	YES
4846797	27118443	PG	2	conducted the database searches|conducted all full-text analyses of articles, extracted the data from included studies, and drafted the tables and manuscript|conceived of the review question and methodology	conducted the database searches	Contributed reagents/materials/analysis tools	Software	YES
4846797	27118443	PG	2	conducted the database searches|conducted all full-text analyses of articles, extracted the data from included studies, and drafted the tables and manuscript|conceived of the review question and methodology	conducted all full-text analyses of articles, extracted the data from included studies, and drafted the tables and manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4846797	27118443	PG	2	conducted the database searches|conducted all full-text analyses of articles, extracted the data from included studies, and drafted the tables and manuscript|conceived of the review question and methodology	conceived of the review question and methodology	Conceived and designed the experiments|Performed the experiments	Conceptualization|Methodology	YES
4846797	27118443	SME	2	conceived of the review question and methodology	conceived of the review question and methodology	Conceived and designed the experiments|Performed the experiments	Conceptualization|Methodology	YES
4846797	27118443	TB	2	conceived of the review question and methodology	conceived of the review question and methodology	Conceived and designed the experiments|Performed the experiments	Conceptualization|Methodology	YES
4405568	25897753	BC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405568	25897753	BC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405568	25897753	BC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405568	25897753	DP	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405568	25897753	DP	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405568	25897753	DP	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405568	25897753	GS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405568	25897753	GS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405568	25897753	GS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405568	25897753	MT	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4405568	25897753	MT	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4405568	25897753	PAS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405568	25897753	PAS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405568	25897753	PAS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405568	25897753	PL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405568	25897753	PL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405568	25897753	PL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405568	25897753	PO	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405568	25897753	SB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405568	25897753	TAK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405568	25897753	TAK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405568	25897753	TAK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405568	25897753	TAK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5543281	28824695	BL	7	Experiment implementation and assistance	Experiment implementation and assistance	Performed the experiments	Investigation	YES
5543281	28824695	FM	7	Experiment design and implementation, composition and review of manuscript, financial support for experiments and laboratory apparatus	Experiment design and implementation, composition and review of manuscript, financial support for experiments and laboratory apparatus	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Funding acquisition|Investigation|Methodology|Writing - Review & Editing	YES
5543281	28824695	NW	7	Experiment design and implementation, manuscript composition	Experiment design and implementation, manuscript composition	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5543281	28824695	PW	7	Experiment implementation and assistance	Experiment implementation and assistance	Performed the experiments	Investigation	YES
5543281	28824695	TG	7	Experiment implementation and assistance	Experiment implementation and assistance	Performed the experiments	Investigation	YES
5543281	28824695	XG	7	Purchase and management of reagents, maintenance of laboratory apparatus	Purchase and management of reagents, maintenance of laboratory apparatus	-	-	NO
5543281	28824695	XJ	7	Experiment implementation and assistance	Experiment implementation and assistance	Performed the experiments	Investigation	YES
5543281	28824695	XS	7	Experiment implementation and assistance	Experiment implementation and assistance	Performed the experiments	Investigation	YES
5543281	28824695	YS	7	Experiment implementation and assistance	Experiment implementation and assistance	Performed the experiments	Investigation	YES
6025126	29561823	E.H.	PLoS52	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6025126	29561823	E.R.H.	PLoS52	analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
6025126	29561823	E.R.H.	PLoS52	analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6025126	29561823	M.M.R.	PLoS52	conceived and designed the study|collected the data|analyzed the data|wrote the paper	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6025126	29561823	M.M.R.	PLoS52	conceived and designed the study|collected the data|analyzed the data|wrote the paper	collected the data	Performed the experiments	Investigation	YES
6025126	29561823	M.M.R.	PLoS52	conceived and designed the study|collected the data|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
6025126	29561823	M.M.R.	PLoS52	conceived and designed the study|collected the data|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5466550	28626581	Jawad Hasnaoui	7	Corresponding author writing the paper	Corresponding author writing the paper	Wrote the paper	Writing - Original Draft	YES
5466550	28626581	Mohammed Mahtar	7	correction of the paper	correction of the paper	Wrote the paper	Writing - Review & Editing	YES
5466550	28626581	Mohammed Roubal	7	correction of the paper	correction of the paper	Wrote the paper	Writing - Review & Editing	YES
5466550	28626581	Mohammed Tatari	7	writing the paper	writing the paper	Wrote the paper	Writing - Original Draft	YES
5466550	28626581	Reda Abada	7	study concept	study concept	Conceived and designed the experiments	Conceptualization	YES
5466550	28626581	Said Anajar	7	writing the paper	writing the paper	Wrote the paper	Writing - Original Draft	YES
5466550	28626581	Sami Rouadi	7	study concept	study concept	Conceived and designed the experiments	Conceptualization	YES
4850147	27125320	AK	2	performed the laboratory and data analysis	performed the laboratory and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4850147	27125320	AS	2	conceived the study, participated in its design and coordination and wrote the manuscript	conceived the study, participated in its design and coordination and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
4850147	27125320	AY	2	enrolled the patients and collected patient data	enrolled the patients and collected patient data	Performed the experiments	Investigation	YES
4850147	27125320	AYD	2	conceived the study, participated in its design and coordination and wrote the manuscript	conceived the study, participated in its design and coordination and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
4850147	27125320	CB	2	performed the laboratory and data analysis	performed the laboratory and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4850147	27125320	ED	2	conceived the study, participated in its design and coordination and wrote the manuscript	conceived the study, participated in its design and coordination and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
4850147	27125320	ET	2	enrolled the patients and collected patient data	enrolled the patients and collected patient data	Performed the experiments	Investigation	YES
4850147	27125320	LS	2	performed the laboratory and data analysis	performed the laboratory and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4850147	27125320	MP	2	conceived the study, participated in its design and coordination and wrote the manuscript	conceived the study, participated in its design and coordination and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
4850147	27125320	MPD	2	conceived the study, participated in its design and coordination and wrote the manuscript	conceived the study, participated in its design and coordination and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
4850147	27125320	MS	2	performed the laboratory and data analysis|conceived the study, participated in its design and coordination and wrote the manuscript	performed the laboratory and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4850147	27125320	MS	2	performed the laboratory and data analysis|conceived the study, participated in its design and coordination and wrote the manuscript	conceived the study, participated in its design and coordination and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
4850147	27125320	NV	2	performed the laboratory and data analysis	performed the laboratory and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4850147	27125320	PP	2	conceived the study, participated in its design and coordination and wrote the manuscript	conceived the study, participated in its design and coordination and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
4850147	27125320	SD	2	enrolled the patients and collected patient data	enrolled the patients and collected patient data	Performed the experiments	Investigation	YES
4850147	27125320	SH	2	enrolled the patients and collected patient data	enrolled the patients and collected patient data	Performed the experiments	Investigation	YES
5301393	28183268	All authors	2	have reviewed the manuscript	have reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5301393	28183268	BC	2	were involved in experimental work and/or data analysis	were involved in experimental work and/or data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5301393	28183268	CC	2	was involved in bioinformatics analysis, manuscript preparation and model construction	was involved in bioinformatics analysis, manuscript preparation and model construction	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5301393	28183268	DvS	2	was involved in idea conception and manuscript editing	was involved in idea conception and manuscript editing	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5301393	28183268	GAL	2	were involved in experimental work and/or data analysis	were involved in experimental work and/or data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5301393	28183268	HN	2	were involved in experimental work and/or data analysis	were involved in experimental work and/or data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5301393	28183268	JM	2	was involved in idea conception, manuscript preparation and experimental work for this study	was involved in idea conception, manuscript preparation and experimental work for this study	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
5301393	28183268	JO	2	were involved in experimental work and/or data analysis	were involved in experimental work and/or data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5301393	28183268	LH	2	were involved in experimental work and/or data analysis	were involved in experimental work and/or data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5301393	28183268	MV	2	were involved in experimental work and/or data analysis	were involved in experimental work and/or data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5301393	28183268	TRK	2	were involved in experimental work and/or data analysis	were involved in experimental work and/or data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4025187	24609467	GS	2	contributed to the day-to-day management of the project, including conceptualization of study methods, preparation of study protocol/statistical analysis plan, conduction of analysis, interpretation/review of analysis, and preparation and review of the manuscript	contributed to the day-to-day management of the project, including conceptualization of study methods, preparation of study protocol/statistical analysis plan, conduction of analysis, interpretation/review of analysis, and preparation and review of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Project administration|Writing - Original Draft|Writing - Review & Editing	YES
4025187	24609467	LR	2	contributed to the conception and design of this study, collaborated on analysis and data interpretation, and actively contributed to and approved the final manuscript version	contributed to the conception and design of this study, collaborated on analysis and data interpretation, and actively contributed to and approved the final manuscript version	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Methodology|Resources|Writing - Review & Editing	YES
4025187	24609467	PS	2	supported the concept development, contributed to study design, endpoint development, and interpretation of results for the mmx mesalazine/pancreatitis evaluation	supported the concept development, contributed to study design, endpoint development, and interpretation of results for the mmx mesalazine/pancreatitis evaluation	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
4025187	24609467	SL	2	contributed to study design, conduct, interpretation and in drafting the report	contributed to study design, conduct, interpretation and in drafting the report	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4025187	24609467	SR	2	contributed to the study conception and data review and was involved in revising the article	contributed to the study conception and data review and was involved in revising the article	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Resources|Writing - Review & Editing	YES
4025187	24609467	UC	2	pancreatitis, and drug-induced pancreatitis	pancreatitis, and drug-induced pancreatitis	-	-	NO
4405569	25897956	CA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405569	25897956	CA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405569	25897956	CA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405569	25897956	CA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405569	25897956	CA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405569	25897956	CEG	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4405569	25897956	CEG	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4405569	25897956	DL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405569	25897956	DL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405569	25897956	DL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405569	25897956	JAS	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405569	25897956	JAS	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405569	25897956	MJH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405569	25897956	MJH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405569	25897956	MJH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405569	25897956	MJH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405569	25897956	MM	PLoS5	Analyzed the data|Website	Analyzed the data	Analyzed the data	Formal analysis	YES
4405569	25897956	MM	PLoS5	Analyzed the data|Website	Website	Contributed reagents/materials/analysis tools	Software	YES
5543283	28824690	HT	PLoS52	conducted the experiment of subcellular localization	conducted the experiment of subcellular localization	Performed the experiments	Investigation	YES
5543283	28824690	JY	PLoS52	conceived and designed this study	conceived and designed this study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5543283	28824690	LZ	PLoS52	conceived and designed this study	conceived and designed this study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5543283	28824690	QL	PLoS52	contributed to data analysis and bioinformatics analysis	contributed to data analysis and bioinformatics analysis	Analyzed the data	Formal analysis	YES
5543283	28824690	RC	PLoS52	contributed to data analysis and bioinformatics analysis	contributed to data analysis and bioinformatics analysis	Analyzed the data	Formal analysis	YES
5543283	28824690	RM	PLoS52	conceived and designed this study|performed the experiments|contributed to data analysis and bioinformatics analysis|wrote the final manuscript and all authors read and approved the final version of the manuscript	conceived and designed this study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5543283	28824690	RM	PLoS52	conceived and designed this study|performed the experiments|contributed to data analysis and bioinformatics analysis|wrote the final manuscript and all authors read and approved the final version of the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5543283	28824690	RM	PLoS52	conceived and designed this study|performed the experiments|contributed to data analysis and bioinformatics analysis|wrote the final manuscript and all authors read and approved the final version of the manuscript	contributed to data analysis and bioinformatics analysis	Analyzed the data	Formal analysis	YES
5543283	28824690	RM	PLoS52	conceived and designed this study|performed the experiments|contributed to data analysis and bioinformatics analysis|wrote the final manuscript and all authors read and approved the final version of the manuscript	wrote the final manuscript and all authors read and approved the final version of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5543283	28824690	WC	PLoS52	conceived and designed this study	conceived and designed this study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5543283	28824690	YX	PLoS52	conceived and designed this study|performed the experiments|wrote the final manuscript and all authors read and approved the final version of the manuscript	conceived and designed this study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5543283	28824690	YX	PLoS52	conceived and designed this study|performed the experiments|wrote the final manuscript and all authors read and approved the final version of the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5543283	28824690	YX	PLoS52	conceived and designed this study|performed the experiments|wrote the final manuscript and all authors read and approved the final version of the manuscript	wrote the final manuscript and all authors read and approved the final version of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5543283	28824690	ZL	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
6025133	29693625	All	2	faculty involved in the training contributed to the development of the interprofessional immersion and the assessment tools used for data collection	faculty involved in the training contributed to the development of the interprofessional immersion and the assessment tools used for data collection	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
6025133	29693625	D.B.	2	completed the irb for this study, conceived and developed framework for this manuscript, and contributed to the largest amount of writing	completed the irb for this study, conceived and developed framework for this manuscript, and contributed to the largest amount of writing	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
6025133	29693625	E.A.	2	analyzed data and provided thorough edits for the manuscript	analyzed data and provided thorough edits for the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
6025133	29693625	T.W.	2	contributed to the literature review and relevant literature within the area of pharmacy	contributed to the literature review and relevant literature within the area of pharmacy	-	Formal analysis	YES
4486761	26161424	Hyun Young Choi	2	contributed equally to this study	contributed equally to this study	-	-	NO
4486761	26161424	Young Min Oh	2	contributed equally to this study	contributed equally to this study	-	-	NO
5301398	28183275	AG	2	performed the data analysis|wrote the manuscript	performed the data analysis	Analyzed the data	Formal analysis	YES
5301398	28183275	AG	2	performed the data analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5301398	28183275	AR	2	managed the entire project|wrote the manuscript	managed the entire project	-	Project administration	YES
5301398	28183275	AR	2	managed the entire project|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5301398	28183275	TH	2	managed the entire project|wrote the manuscript	managed the entire project	-	Project administration	YES
5301398	28183275	TH	2	managed the entire project|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5301398	28183275	UC	2	managed the entire project|wrote the manuscript	managed the entire project	-	Project administration	YES
5301398	28183275	UC	2	managed the entire project|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4405570	25897789	CY	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405570	25897789	DS	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405570	25897789	DS	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405570	25897789	HZ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405570	25897789	IYM	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405570	25897789	JC	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405570	25897789	JC	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405570	25897789	JL	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405570	25897789	JL	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405570	25897789	LL	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405570	25897789	LL	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405570	25897789	MS	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405570	25897789	SL	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405570	25897789	WC	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405570	25897789	WC	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405570	25897789	YG	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405570	25897789	YT	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405570	25897789	ZB	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405570	25897789	ZC	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405570	25897789	ZC	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5470447	28649377	All Authors	2	contributed equally to the preparation, writing and review of this manuscript	contributed equally to the preparation, writing and review of this manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6025166	29857593	All other authors	2	contributed to the data collection and interpretation, and critically reviewed the manuscript	contributed to the data collection and interpretation, and critically reviewed the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
6025166	29857593	R.K.	2	provided all the data and information the revised the manuscript for important intellectual content	provided all the data and information the revised the manuscript for important intellectual content	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Review & Editing	YES
6025166	29857593	T.K.	2	was responsible for the study practice	was responsible for the study practice	-	-	NO
5470525	28649379	A Arora	7	data collection and assisted in writing of article	data collection and assisted in writing of article	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5470525	28649379	A Kythreotou	7	literature search and assisted in writing of article	literature search and assisted in writing of article	Wrote the paper	Formal analysis|Writing - Original Draft	YES
5470525	28649379	B Kotecha	7	conceived paper, reviewed and corrected manuscript. F	conceived paper, reviewed and corrected manuscript. F	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5470525	28649379	C Georgalas	7	data collection and assisted in writing of article	data collection and assisted in writing of article	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5470525	28649379	C Holsinger	7	conceived paper, reviewed and corrected manuscript. D	conceived paper, reviewed and corrected manuscript. D	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5470525	28649379	G Garas	7	conducted literature search, data collection and wrote article	conducted literature search, data collection and wrote article	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5470525	28649379	G Grant	7	conceived paper, reviewed and corrected manuscript	conceived paper, reviewed and corrected manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5470525	28649379	N Tolley	7	conceived paper, reviewed and corrected manuscript	conceived paper, reviewed and corrected manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
4405571	25897517	AD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405571	25897517	AD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405571	25897517	AD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405571	25897517	AD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405571	25897517	MLS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405571	25897517	MLS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405571	25897517	MLS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405571	25897517	MLS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405571	25897517	NTP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405571	25897517	NTP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405571	25897517	NTP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405571	25897517	NTP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405571	25897517	NTP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405571	25897517	TMP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405571	25897517	TMP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405571	25897517	TMP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405571	25897517	TMP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405571	25897517	TMP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4854848	27142091	DHO	2	conceptualized the methodology for the review|contributed to the interpretation of the results and evaluation of the approaches|wrote the first draft of the manuscript|contributed to multiple revisions of the manuscript	conceptualized the methodology for the review	Conceived and designed the experiments|Performed the experiments	Conceptualization|Methodology	YES
4854848	27142091	DHO	2	conceptualized the methodology for the review|contributed to the interpretation of the results and evaluation of the approaches|wrote the first draft of the manuscript|contributed to multiple revisions of the manuscript	contributed to the interpretation of the results and evaluation of the approaches	Analyzed the data	Formal analysis	YES
4854848	27142091	DHO	2	conceptualized the methodology for the review|contributed to the interpretation of the results and evaluation of the approaches|wrote the first draft of the manuscript|contributed to multiple revisions of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
4854848	27142091	DHO	2	conceptualized the methodology for the review|contributed to the interpretation of the results and evaluation of the approaches|wrote the first draft of the manuscript|contributed to multiple revisions of the manuscript	contributed to multiple revisions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4854848	27142091	EET	2	contributed to the interpretation of the results and evaluation of the approaches|contributed to multiple revisions of the manuscript	contributed to the interpretation of the results and evaluation of the approaches	Analyzed the data	Formal analysis	YES
4854848	27142091	EET	2	contributed to the interpretation of the results and evaluation of the approaches|contributed to multiple revisions of the manuscript	contributed to multiple revisions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4854848	27142091	KM	2	contributed to the interpretation of the results and evaluation of the approaches|contributed to multiple revisions of the manuscript	contributed to the interpretation of the results and evaluation of the approaches	Analyzed the data	Formal analysis	YES
4854848	27142091	KM	2	contributed to the interpretation of the results and evaluation of the approaches|contributed to multiple revisions of the manuscript	contributed to multiple revisions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4854848	27142091	RMS	2	conceptualized the methodology for the review|contributed to the interpretation of the results and evaluation of the approaches|wrote the first draft of the manuscript|contributed to multiple revisions of the manuscript	conceptualized the methodology for the review	Conceived and designed the experiments|Performed the experiments	Conceptualization|Methodology	YES
4854848	27142091	RMS	2	conceptualized the methodology for the review|contributed to the interpretation of the results and evaluation of the approaches|wrote the first draft of the manuscript|contributed to multiple revisions of the manuscript	contributed to the interpretation of the results and evaluation of the approaches	Analyzed the data	Formal analysis	YES
4854848	27142091	RMS	2	conceptualized the methodology for the review|contributed to the interpretation of the results and evaluation of the approaches|wrote the first draft of the manuscript|contributed to multiple revisions of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
4854848	27142091	RMS	2	conceptualized the methodology for the review|contributed to the interpretation of the results and evaluation of the approaches|wrote the first draft of the manuscript|contributed to multiple revisions of the manuscript	contributed to multiple revisions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4854848	27142091	TRM	2	contributed to the interpretation of the results and evaluation of the approaches|contributed to multiple revisions of the manuscript	contributed to the interpretation of the results and evaluation of the approaches	Analyzed the data	Formal analysis	YES
4854848	27142091	TRM	2	contributed to the interpretation of the results and evaluation of the approaches|contributed to multiple revisions of the manuscript	contributed to multiple revisions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5303218	28187711	AV	2	designed the software|implemented poppante, and performed the computational experiments|wrote the manuscript	designed the software	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
5303218	28187711	AV	2	designed the software|implemented poppante, and performed the computational experiments|wrote the manuscript	implemented poppante, and performed the computational experiments	Performed the experiments	Formal analysis|Investigation	YES
5303218	28187711	AV	2	designed the software|implemented poppante, and performed the computational experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5303218	28187711	All authors	2	read, commented, and approved the final manuscript	read, commented, and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5303218	28187711	KS	2	generated the qatari family study data	generated the qatari family study data	Performed the experiments	Investigation	YES
5303218	28187711	MAS	2	generated the qatari family study data	generated the qatari family study data	Performed the experiments	Investigation	YES
5303218	28187711	MF	2	designed the software|wrote the manuscript	designed the software	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
5303218	28187711	MF	2	designed the software|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5303218	28187711	MM	2	provided the data for the twinsuk cohort, and tested the software	provided the data for the twinsuk cohort, and tested the software	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources|Software	YES
5303218	28187711	SBZ	2	generated the qatari family study data	generated the qatari family study data	Performed the experiments	Investigation	YES
5303218	28187711	WAAM	2	generated the qatari family study data	generated the qatari family study data	Performed the experiments	Investigation	YES
6025216	29786638	L.S.	PLoS52	conceived the study idea and design	conceived the study idea and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6025216	29786638	M.H.	PLoS52	conceived the study idea and design	conceived the study idea and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6025216	29786638	N.D.	PLoS52	analyzed the data|composed the publication	analyzed the data	Analyzed the data	Formal analysis	YES
6025216	29786638	N.D.	PLoS52	analyzed the data|composed the publication	composed the publication	-	-	NO
6025216	29786638	S.L.	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5545584	28824660	AB	2	designed the article|corrected the article and finally all authors read and approved the final article	designed the article	Conceived and designed the experiments	-	YES
5545584	28824660	AB	2	designed the article|corrected the article and finally all authors read and approved the final article	corrected the article and finally all authors read and approved the final article	Wrote the paper	Writing - Review & Editing	YES
5545584	28824660	AK	2	designed the article|wrote the article	designed the article	Conceived and designed the experiments	-	YES
5545584	28824660	AK	2	designed the article|wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
5545584	28824660	AP	2	corrected the article and finally all authors read and approved the final article	corrected the article and finally all authors read and approved the final article	Wrote the paper	Writing - Review & Editing	YES
5545584	28824660	MKP	2	designed the article|corrected the article and finally all authors read and approved the final article	designed the article	Conceived and designed the experiments	-	YES
5545584	28824660	MKP	2	designed the article|corrected the article and finally all authors read and approved the final article	corrected the article and finally all authors read and approved the final article	Wrote the paper	Writing - Review & Editing	YES
5545584	28824660	RK	2	designed the article|wrote the article|corrected the article and finally all authors read and approved the final article	designed the article	Conceived and designed the experiments	-	YES
5545584	28824660	RK	2	designed the article|wrote the article|corrected the article and finally all authors read and approved the final article	wrote the article	Wrote the paper	Writing - Original Draft	YES
5545584	28824660	RK	2	designed the article|wrote the article|corrected the article and finally all authors read and approved the final article	corrected the article and finally all authors read and approved the final article	Wrote the paper	Writing - Review & Editing	YES
4862966	27166355	AMA	2	each reviewed the literature and wrote the manuscript	each reviewed the literature and wrote the manuscript	Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
4862966	27166355	RFS	2	each reviewed the literature and wrote the manuscript	each reviewed the literature and wrote the manuscript	Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
4862966	27166355	WRT	2	each reviewed the literature and wrote the manuscript	each reviewed the literature and wrote the manuscript	Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
4405572	25898364	CS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4405572	25898364	CS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405572	25898364	KH	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405572	25898364	KH	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405572	25898364	MB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405572	25898364	MB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405572	25898364	MB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405572	25898364	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405572	25898364	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405572	25898364	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405572	25898364	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405572	25898364	MP	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405572	25898364	MP	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405572	25898364	RAC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405572	25898364	RAC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405572	25898364	RAC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405572	25898364	SQ	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4405572	25898364	SQ	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4405572	25898364	UM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405572	25898364	UM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405572	25898364	UM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5476974	28652912	Thawatchai Tullavardhana	2	contribution of the authors as mentioned below with their responsibility in the research	contribution of the authors as mentioned below with their responsibility in the research	-	-	NO
4487700	26161426	Changsun Kim	2	were involved in study concept and design, interpretation of the data, critical revision of the paper for important intellectual content, and final approval of the version to be published	were involved in study concept and design, interpretation of the data, critical revision of the paper for important intellectual content, and final approval of the version to be published	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Review & Editing	YES
4487700	26161426	Hyunggoo Kang	2	were involved in critical revision of the paper for important intellectual content	were involved in critical revision of the paper for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4487700	26161426	Jaehoon Oh	2	were involved in study concept and design, interpretation of the data, critical revision of the paper for important intellectual content, and final approval of the version to be published	were involved in study concept and design, interpretation of the data, critical revision of the paper for important intellectual content, and final approval of the version to be published	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Review & Editing	YES
4487700	26161426	Jun Hwi Cho	2	were involved in critical revision of the paper for important intellectual content	were involved in critical revision of the paper for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4487700	26161426	Sanghyun Lee	2	contributed equally to this study|were involved in all aspects of the study design, designing and managing the study, interpreting findings, and cowriting the paper	contributed equally to this study	-	-	NO
4487700	26161426	Sanghyun Lee	2	contributed equally to this study|were involved in all aspects of the study design, designing and managing the study, interpreting findings, and cowriting the paper	were involved in all aspects of the study design, designing and managing the study, interpreting findings, and cowriting the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4487700	26161426	Tae Ho Lim	2	were involved in study concept and design, interpretation of the data, critical revision of the paper for important intellectual content, and final approval of the version to be published	were involved in study concept and design, interpretation of the data, critical revision of the paper for important intellectual content, and final approval of the version to be published	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Review & Editing	YES
4487700	26161426	Wonhee Kim	2	contributed equally to this study|were involved in all aspects of the study design, designing and managing the study, interpreting findings, and cowriting the paper	contributed equally to this study	-	-	NO
4487700	26161426	Wonhee Kim	2	contributed equally to this study|were involved in all aspects of the study design, designing and managing the study, interpreting findings, and cowriting the paper	were involved in all aspects of the study design, designing and managing the study, interpreting findings, and cowriting the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4487700	26161426	Yoonjae Lee	2	were involved in critical revision of the paper for important intellectual content	were involved in critical revision of the paper for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
6025221	29895734	L.C.	2	edited the manuscripts	edited the manuscripts	Wrote the paper	Writing - Review & Editing	YES
6025221	29895734	Lita Chew	2	conceived and designed the colloquium	conceived and designed the colloquium	Conceived and designed the experiments	Conceptualization	YES
6025221	29895734	R.P.	2	presented the papers|wrote the papers	presented the papers	-	-	NO
6025221	29895734	R.P.	2	presented the papers|wrote the papers	wrote the papers	Wrote the paper	Writing - Original Draft	YES
5303225	28187704	JB	1	Initiated the project and wrote the paper|Evolutionary analyses|Statistical analyses	Initiated the project and wrote the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5303225	28187704	JB	1	Initiated the project and wrote the paper|Evolutionary analyses|Statistical analyses	Evolutionary analyses	Analyzed the data	Formal analysis	YES
5303225	28187704	JB	1	Initiated the project and wrote the paper|Evolutionary analyses|Statistical analyses	Statistical analyses	Analyzed the data	Formal analysis	YES
5303225	28187704	JP	1	Evolutionary analyses	Evolutionary analyses	Analyzed the data	Formal analysis	YES
5303225	28187704	LS	1	Statistical analyses|Pan genomic analyses	Statistical analyses	Analyzed the data	Formal analysis	YES
5303225	28187704	LS	1	Statistical analyses|Pan genomic analyses	Pan genomic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5303225	28187704	OB	1	Evolutionary analyses	Evolutionary analyses	Analyzed the data	Formal analysis	YES
5303225	28187704	VE	1	Evolutionary analyses	Evolutionary analyses	Analyzed the data	Formal analysis	YES
5550412	28848574	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5550412	28848574	CZ	2	designed research scheme|revised it	designed research scheme	Conceived and designed the experiments	Methodology	YES
5550412	28848574	CZ	2	designed research scheme|revised it	revised it	Wrote the paper	Writing - Review & Editing	YES
5550412	28848574	FZ	2	revised it	revised it	Wrote the paper	Writing - Review & Editing	YES
5550412	28848574	GY	2	revised it	revised it	Wrote the paper	Writing - Review & Editing	YES
5550412	28848574	HS	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5550412	28848574	JB	2	designed research scheme|performed experiments|analyzed data|wrote the manuscript|revised it	designed research scheme	Conceived and designed the experiments	Methodology	YES
5550412	28848574	JB	2	designed research scheme|performed experiments|analyzed data|wrote the manuscript|revised it	performed experiments	Performed the experiments	Investigation	YES
5550412	28848574	JB	2	designed research scheme|performed experiments|analyzed data|wrote the manuscript|revised it	analyzed data	Analyzed the data	Formal analysis	YES
5550412	28848574	JB	2	designed research scheme|performed experiments|analyzed data|wrote the manuscript|revised it	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5550412	28848574	JB	2	designed research scheme|performed experiments|analyzed data|wrote the manuscript|revised it	revised it	Wrote the paper	Writing - Review & Editing	YES
5550412	28848574	JM	2	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5550412	28848574	LZ	2	designed research scheme|revised it	designed research scheme	Conceived and designed the experiments	Methodology	YES
5550412	28848574	LZ	2	designed research scheme|revised it	revised it	Wrote the paper	Writing - Review & Editing	YES
5550412	28848574	NW	2	revised it	revised it	Wrote the paper	Writing - Review & Editing	YES
5550412	28848574	PW	2	performed experiments|analyzed data|wrote the manuscript|revised it	performed experiments	Performed the experiments	Investigation	YES
5550412	28848574	PW	2	performed experiments|analyzed data|wrote the manuscript|revised it	analyzed data	Analyzed the data	Formal analysis	YES
5550412	28848574	PW	2	performed experiments|analyzed data|wrote the manuscript|revised it	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5550412	28848574	PW	2	performed experiments|analyzed data|wrote the manuscript|revised it	revised it	Wrote the paper	Writing - Review & Editing	YES
5550412	28848574	SY	2	performed experiments|revised it	performed experiments	Performed the experiments	Investigation	YES
5550412	28848574	SY	2	performed experiments|revised it	revised it	Wrote the paper	Writing - Review & Editing	YES
5550412	28848574	WD	2	performed experiments|analyzed data	performed experiments	Performed the experiments	Investigation	YES
5550412	28848574	WD	2	performed experiments|analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5550412	28848574	YW	2	designed research scheme|performed experiments|analyzed data|wrote the manuscript|revised it	designed research scheme	Conceived and designed the experiments	Methodology	YES
5550412	28848574	YW	2	designed research scheme|performed experiments|analyzed data|wrote the manuscript|revised it	performed experiments	Performed the experiments	Investigation	YES
5550412	28848574	YW	2	designed research scheme|performed experiments|analyzed data|wrote the manuscript|revised it	analyzed data	Analyzed the data	Formal analysis	YES
5550412	28848574	YW	2	designed research scheme|performed experiments|analyzed data|wrote the manuscript|revised it	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5550412	28848574	YW	2	designed research scheme|performed experiments|analyzed data|wrote the manuscript|revised it	revised it	Wrote the paper	Writing - Review & Editing	YES
4865806	27174911	ASK	2	contributed to design and execution of the study|performed the mathematical modelling analyses|parameterized the model	contributed to design and execution of the study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4865806	27174911	ASK	2	contributed to design and execution of the study|performed the mathematical modelling analyses|parameterized the model	performed the mathematical modelling analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
4865806	27174911	ASK	2	contributed to design and execution of the study|performed the mathematical modelling analyses|parameterized the model	parameterized the model	Performed the experiments	Methodology	YES
4865806	27174911	All authors	2	contributed to the interpretation of findings and read and approved the final version of the article for submission	contributed to the interpretation of findings and read and approved the final version of the article for submission	Analyzed the data	Formal analysis	YES
4865806	27174911	RVB	2	contributed to design and execution of the study|which was then revised by all authors	contributed to design and execution of the study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4865806	27174911	RVB	2	contributed to design and execution of the study|which was then revised by all authors	which was then revised by all authors	Wrote the paper	Writing - Review & Editing	YES
4865806	27174911	SC	2	contributed to design and execution of the study	contributed to design and execution of the study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4865806	27174911	STR	2	contributed to design and execution of the study|parameterized the model	contributed to design and execution of the study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4865806	27174911	STR	2	contributed to design and execution of the study|parameterized the model	parameterized the model	Performed the experiments	Methodology	YES
4088993	24839948	Catherine Dutreix	7	Conception and design, acquisition of data, analysis and interpretation of data, drafting of the manuscript, critical revision of the manuscript for important intellectual content, and final approval of the manuscript	Conception and design, acquisition of data, analysis and interpretation of data, drafting of the manuscript, critical revision of the manuscript for important intellectual content, and final approval of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
4088993	24839948	Sebastien Lorenzo	7	Conception and design, acquisition of data, analysis and interpretation of data, drafting of the manuscript, critical revision of the manuscript for important intellectual content, and final approval of the manuscript	Conception and design, acquisition of data, analysis and interpretation of data, drafting of the manuscript, critical revision of the manuscript for important intellectual content, and final approval of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
4088993	24839948	Yanfeng Wang	7	Conception and design, acquisition of data, analysis and interpretation of data, drafting the manuscript, critical revision of the manuscript for important intellectual content, and final approval of the manuscript	Conception and design, acquisition of data, analysis and interpretation of data, drafting the manuscript, critical revision of the manuscript for important intellectual content, and final approval of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
4405573	25897844	CCL	PLoS5	Data analysis and interpretation	Data analysis and interpretation	Analyzed the data	Formal analysis	YES
4405573	25897844	HJL	PLoS5	Conceived and designed the experiments|Wrote the paper|Data analysis and interpretation	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405573	25897844	HJL	PLoS5	Conceived and designed the experiments|Wrote the paper|Data analysis and interpretation	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405573	25897844	HJL	PLoS5	Conceived and designed the experiments|Wrote the paper|Data analysis and interpretation	Data analysis and interpretation	Analyzed the data	Formal analysis	YES
4405573	25897844	MCH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Data analysis and interpretation	Performed the experiments	Performed the experiments	Investigation	YES
4405573	25897844	MCH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Data analysis and interpretation	Analyzed the data	Analyzed the data	Formal analysis	YES
4405573	25897844	MCH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Data analysis and interpretation	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405573	25897844	MCH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Data analysis and interpretation	Data analysis and interpretation	Analyzed the data	Formal analysis	YES
4405573	25897844	PJL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Data analysis and interpretation	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405573	25897844	PJL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Data analysis and interpretation	Performed the experiments	Performed the experiments	Investigation	YES
4405573	25897844	PJL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Data analysis and interpretation	Analyzed the data	Analyzed the data	Formal analysis	YES
4405573	25897844	PJL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Data analysis and interpretation	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405573	25897844	PJL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Data analysis and interpretation	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405573	25897844	PJL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Data analysis and interpretation	Data analysis and interpretation	Analyzed the data	Formal analysis	YES
4405573	25897844	PJM	PLoS5	Data analysis and interpretation	Data analysis and interpretation	Analyzed the data	Formal analysis	YES
4405573	25897844	TYF	PLoS5	Data analysis and interpretation	Data analysis and interpretation	Analyzed the data	Formal analysis	YES
4405573	25897844	YHH	PLoS5	Performed the experiments|Data analysis and interpretation	Performed the experiments	Performed the experiments	Investigation	YES
4405573	25897844	YHH	PLoS5	Performed the experiments|Data analysis and interpretation	Data analysis and interpretation	Analyzed the data	Formal analysis	YES
5550670	28848592	DH	7	performed research, analyzed data	performed research, analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5550670	28848592	G-AL	7	performed research, analyzed data, wrote the paper	performed research, analyzed data, wrote the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5550670	28848592	H-JK	7	designed research, performed research, wrote the paper	designed research, performed research, wrote the paper	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5550670	28848592	H-SL	7	performed research, wrote the paper	performed research, wrote the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5550670	28848592	J-RL	7	performed research, analyzed data	performed research, analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5550670	28848592	K-HM	7	designed research, performed research	designed research, performed research	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5550670	28848592	M-CL	7	performed research, analyzed data	performed research, analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5550670	28848592	S-YL	7	designed research, performed research	designed research, performed research	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5550670	28848592	Y-AJ	7	phenotyped samples, analyzed data	phenotyped samples, analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5479941	28663795	All	2	contributors have been mentioned at the end of the article	contributors have been mentioned at the end of the article	-	-	NO
6025262	29597245	N.S.	PLoS52	analysed the data|wrote the paper	analysed the data	Analyzed the data	Formal analysis	YES
6025262	29597245	N.S.	PLoS52	analysed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6025262	29597245	S.H.S.	PLoS52	analysed the data|reviewed the paper	analysed the data	Analyzed the data	Formal analysis	YES
6025262	29597245	S.H.S.	PLoS52	analysed the data|reviewed the paper	reviewed the paper	Wrote the paper	Writing - Review & Editing	YES
4870383	27189531	AB	2	critically reviewed the data analysis and appraised the manuscript	critically reviewed the data analysis and appraised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4870383	27189531	All authors	2	contributed significantly to the study design and writing the article	contributed significantly to the study design and writing the article	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4870383	27189531	CJ	2	critically reviewed the data analysis and appraised the manuscript	critically reviewed the data analysis and appraised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4870383	27189531	EN	2	critically reviewed the data analysis and appraised the manuscript	critically reviewed the data analysis and appraised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4870383	27189531	HB	2	critically reviewed the data analysis and appraised the manuscript	critically reviewed the data analysis and appraised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4870383	27189531	MB	2	wrote the first draft of the manuscript|initially reviewed and analyzed the relevant data	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
4870383	27189531	MB	2	wrote the first draft of the manuscript|initially reviewed and analyzed the relevant data	initially reviewed and analyzed the relevant data	Analyzed the data	Formal analysis	YES
4870383	27189531	MBi	2	critically reviewed the data analysis and appraised the manuscript|gave technical support and conceptual advice on the structure of this paper	critically reviewed the data analysis and appraised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4870383	27189531	MBi	2	critically reviewed the data analysis and appraised the manuscript|gave technical support and conceptual advice on the structure of this paper	gave technical support and conceptual advice on the structure of this paper	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
4870383	27189531	NF	2	critically reviewed the data analysis and appraised the manuscript|gave technical support and conceptual advice on the structure of this paper	critically reviewed the data analysis and appraised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4870383	27189531	NF	2	critically reviewed the data analysis and appraised the manuscript|gave technical support and conceptual advice on the structure of this paper	gave technical support and conceptual advice on the structure of this paper	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
4870383	27189531	SB	2	wrote the first draft of the manuscript|initially reviewed and analyzed the relevant data	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
4870383	27189531	SB	2	wrote the first draft of the manuscript|initially reviewed and analyzed the relevant data	initially reviewed and analyzed the relevant data	Analyzed the data	Formal analysis	YES
4870383	27189531	TE	2	critically reviewed the data analysis and appraised the manuscript	critically reviewed the data analysis and appraised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4870383	27189531	TVDA	2	gave technical support and conceptual advice on the structure of this paper	gave technical support and conceptual advice on the structure of this paper	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
4870383	27189531	TvdA	2	critically reviewed the data analysis and appraised the manuscript	critically reviewed the data analysis and appraised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4870383	27189531	all authors	2	have read and approved the final version	have read and approved the final version	-	-	NO
4405574	25897495	ACMC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405574	25897495	ACMC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4405574	25897495	ACMC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4405574	25897495	EW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405574	25897495	EW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4405574	25897495	EW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405574	25897495	GV	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4405574	25897495	PS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405574	25897495	PS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405574	25897495	PS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405574	25897495	PS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405574	25897495	VK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5480815	28663796	Christopher Okeahialam	1	Data collection|Critical revision	Data collection	Performed the experiments	Investigation	YES
5480815	28663796	Christopher Okeahialam	1	Data collection|Critical revision	Critical revision	Wrote the paper	Writing - Review & Editing	YES
5480815	28663796	Corrine Quinn	1	Study design|Critical revision	Study design	Conceived and designed the experiments	Methodology	YES
5480815	28663796	Corrine Quinn	1	Study design|Critical revision	Critical revision	Wrote the paper	Writing - Review & Editing	YES
5480815	28663796	Dane Moran	1	Data collection|Data analysis|Manuscript preparation	Data collection	Performed the experiments	Investigation	YES
5480815	28663796	Dane Moran	1	Data collection|Data analysis|Manuscript preparation	Data analysis	Analyzed the data	Formal analysis	YES
5480815	28663796	Dane Moran	1	Data collection|Data analysis|Manuscript preparation	Manuscript preparation	Wrote the paper	Writing - Original Draft	YES
5480815	28663796	Iyad Eid	1	Data collection|Critical revision	Data collection	Performed the experiments	Investigation	YES
5480815	28663796	Iyad Eid	1	Data collection|Critical revision	Critical revision	Wrote the paper	Writing - Review & Editing	YES
5480815	28663796	Michael H. Johnson	1	Study design|Critical revision	Study design	Conceived and designed the experiments	Methodology	YES
5480815	28663796	Michael H. Johnson	1	Study design|Critical revision	Critical revision	Wrote the paper	Writing - Review & Editing	YES
5480815	28663796	Rabie Kilan	1	Study design|Data collection|Critical revision	Study design	Conceived and designed the experiments	Methodology	YES
5480815	28663796	Rabie Kilan	1	Study design|Data collection|Critical revision	Data collection	Performed the experiments	Investigation	YES
5480815	28663796	Rabie Kilan	1	Study design|Data collection|Critical revision	Critical revision	Wrote the paper	Writing - Review & Editing	YES
5480815	28663796	Tammy Williams	1	Data collection|Critical revision	Data collection	Performed the experiments	Investigation	YES
5480815	28663796	Tammy Williams	1	Data collection|Critical revision	Critical revision	Wrote the paper	Writing - Review & Editing	YES
5480815	28663796	Wadie Binsaddiq	1	Study design|Critical revision	Study design	Conceived and designed the experiments	Methodology	YES
5480815	28663796	Wadie Binsaddiq	1	Study design|Critical revision	Critical revision	Wrote the paper	Writing - Review & Editing	YES
5303240	28187707	CZ	2	participated in the design of the study and assisted with the experiments	participated in the design of the study and assisted with the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5303240	28187707	FW	2	carried out the animal experiments and obtained samples for rna extraction|performed the transcriptomes sequencing and microarray experiments|performed bioinformatics analyses|performed qrt pcr, in situ hybridization and immunohistochemical analysis|made substantial contributions to the data analysis|drafted the manuscript	carried out the animal experiments and obtained samples for rna extraction	Performed the experiments	Investigation	YES
5303240	28187707	FW	2	carried out the animal experiments and obtained samples for rna extraction|performed the transcriptomes sequencing and microarray experiments|performed bioinformatics analyses|performed qrt pcr, in situ hybridization and immunohistochemical analysis|made substantial contributions to the data analysis|drafted the manuscript	performed the transcriptomes sequencing and microarray experiments	Performed the experiments	Investigation	YES
5303240	28187707	FW	2	carried out the animal experiments and obtained samples for rna extraction|performed the transcriptomes sequencing and microarray experiments|performed bioinformatics analyses|performed qrt pcr, in situ hybridization and immunohistochemical analysis|made substantial contributions to the data analysis|drafted the manuscript	performed bioinformatics analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5303240	28187707	FW	2	carried out the animal experiments and obtained samples for rna extraction|performed the transcriptomes sequencing and microarray experiments|performed bioinformatics analyses|performed qrt pcr, in situ hybridization and immunohistochemical analysis|made substantial contributions to the data analysis|drafted the manuscript	performed qrt pcr, in situ hybridization and immunohistochemical analysis	Performed the experiments	Investigation	YES
5303240	28187707	FW	2	carried out the animal experiments and obtained samples for rna extraction|performed the transcriptomes sequencing and microarray experiments|performed bioinformatics analyses|performed qrt pcr, in situ hybridization and immunohistochemical analysis|made substantial contributions to the data analysis|drafted the manuscript	made substantial contributions to the data analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5303240	28187707	FW	2	carried out the animal experiments and obtained samples for rna extraction|performed the transcriptomes sequencing and microarray experiments|performed bioinformatics analyses|performed qrt pcr, in situ hybridization and immunohistochemical analysis|made substantial contributions to the data analysis|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5303240	28187707	JD	2	made substantial contributions to the data analysis	made substantial contributions to the data analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5303240	28187707	JW	2	participated in the design of the study and assisted with the experiments	participated in the design of the study and assisted with the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5303240	28187707	MY	2	performed qrt pcr, in situ hybridization and immunohistochemical analysis	performed qrt pcr, in situ hybridization and immunohistochemical analysis	Performed the experiments	Investigation	YES
5303240	28187707	SW	2	performed bioinformatics analyses|drafted the manuscript|designed the research, analysed the data, and obtained funding	performed bioinformatics analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5303240	28187707	SW	2	performed bioinformatics analyses|drafted the manuscript|designed the research, analysed the data, and obtained funding	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5303240	28187707	SW	2	performed bioinformatics analyses|drafted the manuscript|designed the research, analysed the data, and obtained funding	designed the research, analysed the data, and obtained funding	Conceived and designed the experiments|Analyzed the data	Formal analysis|Funding acquisition|Methodology	YES
5303240	28187707	WC	2	carried out the animal experiments and obtained samples for rna extraction	carried out the animal experiments and obtained samples for rna extraction	Performed the experiments	Investigation	YES
5303240	28187707	XW	2	performed qrt pcr, in situ hybridization and immunohistochemical analysis	performed qrt pcr, in situ hybridization and immunohistochemical analysis	Performed the experiments	Investigation	YES
5303240	28187707	YL	2	carried out the animal experiments and obtained samples for rna extraction|performed bioinformatics analyses	carried out the animal experiments and obtained samples for rna extraction	Performed the experiments	Investigation	YES
5303240	28187707	YL	2	carried out the animal experiments and obtained samples for rna extraction|performed bioinformatics analyses	performed bioinformatics analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5303240	28187707	ZF	2	carried out the animal experiments and obtained samples for rna extraction|performed the transcriptomes sequencing and microarray experiments|made substantial contributions to the data analysis	carried out the animal experiments and obtained samples for rna extraction	Performed the experiments	Investigation	YES
5303240	28187707	ZF	2	carried out the animal experiments and obtained samples for rna extraction|performed the transcriptomes sequencing and microarray experiments|made substantial contributions to the data analysis	performed the transcriptomes sequencing and microarray experiments	Performed the experiments	Investigation	YES
5303240	28187707	ZF	2	carried out the animal experiments and obtained samples for rna extraction|performed the transcriptomes sequencing and microarray experiments|made substantial contributions to the data analysis	made substantial contributions to the data analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5550681	28848586	JL	2	designed the research|conducted the research	designed the research	Conceived and designed the experiments	Methodology	YES
5550681	28848586	JL	2	designed the research|conducted the research	conducted the research	Performed the experiments	Investigation	YES
5550681	28848586	JY	2	designed the research|conducted the research	designed the research	Conceived and designed the experiments	Methodology	YES
5550681	28848586	JY	2	designed the research|conducted the research	conducted the research	Performed the experiments	Investigation	YES
5550681	28848586	LX	2	designed the research|wrote the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
5550681	28848586	LX	2	designed the research|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5550681	28848586	PQ	2	designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
5550681	28848586	WL	2	designed the research|conducted the research	designed the research	Conceived and designed the experiments	Methodology	YES
5550681	28848586	WL	2	designed the research|conducted the research	conducted the research	Performed the experiments	Investigation	YES
6025264	29693570	A Echtenkamp	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6025264	29693570	All authors	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6025264	29693570	J Lampkin	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
6025264	29693570	K Hassan	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
4158172	25146692	Amanda Peppercorn	2	designed the study, analysed the data and prepared the manuscript	designed the study, analysed the data and prepared the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4158172	25146692	DTG	2	prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
4158172	25146692	David Wilfret	2	designed the study, analysed the data and prepared the manuscript	designed the study, analysed the data and prepared the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4158172	25146692	Ivy Song	2	designed the study, analysed the data and prepared the manuscript	designed the study, analysed the data and prepared the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4158172	25146692	Julie Borland	2	designed the study, analysed the data and prepared the manuscript	designed the study, analysed the data and prepared the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4158172	25146692	Justin P. Rubio	2	performed the pharmacogenetic analysis and prepared the manuscript	performed the pharmacogenetic analysis and prepared the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4158172	25146692	Louise Hosking	2	performed the pharmacogenetic analysis and prepared the manuscript	performed the pharmacogenetic analysis and prepared the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4158172	25146692	Michael Mosteller	2	performed the pharmacogenetic analysis and prepared the manuscript	performed the pharmacogenetic analysis and prepared the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4158172	25146692	Paul Savina	2	designed the study, analysed the data and prepared the manuscript	designed the study, analysed the data and prepared the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4158172	25146692	Phyllis Guta	2	designed the study, analysed the data and prepared the manuscript	designed the study, analysed the data and prepared the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4158172	25146692	Shuguang Chen	2	designed the study, analysed the data and prepared the manuscript	designed the study, analysed the data and prepared the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4158172	25146692	Stephen C. Piscitelli	2	designed the study, analysed the data and prepared the manuscript	designed the study, analysed the data and prepared the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4158172	25146692	Toshihiro Wajima	2	designed the study, analysed the data and prepared the manuscript	designed the study, analysed the data and prepared the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4158172	25146692	Yu Lou	2	designed the study, analysed the data and prepared the manuscript	designed the study, analysed the data and prepared the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5484968	28702182	Hiroyasu Nakashima	2	contributed in the conception and design of the study, drafting and revision the article, final approval of the version to be submitted	contributed in the conception and design of the study, drafting and revision the article, final approval of the version to be submitted	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5484968	28702182	Kazu Shiomi	2	contributed in the conception and design of the study, drafting and revision the article, supervision of the study, and final approval of the version to be submitted	contributed in the conception and design of the study, drafting and revision the article, supervision of the study, and final approval of the version to be submitted	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
5484968	28702182	Masanori Naito	2	contributed in the conception and design of the study, drafting and revision the article, final approval of the version to be submitted	contributed in the conception and design of the study, drafting and revision the article, final approval of the version to be submitted	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5484968	28702182	Takatoshi Nakamura	2	contributed in the conception and design of the study, drafting and revision the article, final approval of the version to be submitted	contributed in the conception and design of the study, drafting and revision the article, final approval of the version to be submitted	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5484968	28702182	Takeo Sato	2	contributed in the conception and design of the study, drafting and revision the article, final approval of the version to be submitted	contributed in the conception and design of the study, drafting and revision the article, final approval of the version to be submitted	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5303294	28187716	AL	PLoS52	designed the research|analyzed the data|wrote the paper	designed the research	Conceived and designed the experiments	Methodology	YES
5303294	28187716	AL	PLoS52	designed the research|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5303294	28187716	AL	PLoS52	designed the research|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5303294	28187716	DL	PLoS52	designed the research|wrote the paper	designed the research	Conceived and designed the experiments	Methodology	YES
5303294	28187716	DL	PLoS52	designed the research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5303294	28187716	DZ	PLoS52	performed the research	performed the research	Performed the experiments	Investigation	YES
5303294	28187716	HZhang	PLoS52	designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
5303294	28187716	HZheng	PLoS52	designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
5303294	28187716	JL	PLoS52	performed the research	performed the research	Performed the experiments	Investigation	YES
5303294	28187716	LM	PLoS52	designed the research|wrote the paper	designed the research	Conceived and designed the experiments	Methodology	YES
5303294	28187716	LM	PLoS52	designed the research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5303294	28187716	LZ	PLoS52	performed the research	performed the research	Performed the experiments	Investigation	YES
5303294	28187716	MH	PLoS52	designed the research|performed the research|analyzed the data|wrote the paper	designed the research	Conceived and designed the experiments	Methodology	YES
5303294	28187716	MH	PLoS52	designed the research|performed the research|analyzed the data|wrote the paper	performed the research	Performed the experiments	Investigation	YES
5303294	28187716	MH	PLoS52	designed the research|performed the research|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5303294	28187716	MH	PLoS52	designed the research|performed the research|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5303294	28187716	TS	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5303294	28187716	XK	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5303294	28187716	XLan	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5303294	28187716	XLi	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5303294	28187716	XZ	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5303294	28187716	YZ	PLoS52	designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
4870384	27189532	AFdV	PLoS52	interpreted the data	interpreted the data	Analyzed the data	Formal analysis	YES
4870384	27189532	AJH	PLoS52	interpreted the data|wrote the first draft of the paper	interpreted the data	Analyzed the data	Formal analysis	YES
4870384	27189532	AJH	PLoS52	interpreted the data|wrote the first draft of the paper	wrote the first draft of the paper	Wrote the paper	Writing - Original Draft	YES
4870384	27189532	All authors	PLoS52	discussed the results and implications and commented on the final version of the manuscript	discussed the results and implications and commented on the final version of the manuscript	-	-	NO
4870384	27189532	MAH	PLoS52	designed the study|performed the experiments|interpreted the data|wrote the first draft of the paper	designed the study	Conceived and designed the experiments	Methodology	YES
4870384	27189532	MAH	PLoS52	designed the study|performed the experiments|interpreted the data|wrote the first draft of the paper	performed the experiments	Performed the experiments	Investigation	YES
4870384	27189532	MAH	PLoS52	designed the study|performed the experiments|interpreted the data|wrote the first draft of the paper	interpreted the data	Analyzed the data	Formal analysis	YES
4870384	27189532	MAH	PLoS52	designed the study|performed the experiments|interpreted the data|wrote the first draft of the paper	wrote the first draft of the paper	Wrote the paper	Writing - Original Draft	YES
4870384	27189532	MPG	PLoS52	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
4870384	27189532	TvdP	PLoS52	designed the study|interpreted the data|wrote the first draft of the paper	designed the study	Conceived and designed the experiments	Methodology	YES
4870384	27189532	TvdP	PLoS52	designed the study|interpreted the data|wrote the first draft of the paper	interpreted the data	Analyzed the data	Formal analysis	YES
4870384	27189532	TvdP	PLoS52	designed the study|interpreted the data|wrote the first draft of the paper	wrote the first draft of the paper	Wrote the paper	Writing - Original Draft	YES
4405575	25898319	WL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405575	25898319	WL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405575	25898319	WL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405575	25898319	YK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405575	25898319	YK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405575	25898319	YK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405575	25898319	YK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5550687	28848596	CT	2	performed and analyzed the biochemical, physiological, morphological, and yield traits	performed and analyzed the biochemical, physiological, morphological, and yield traits	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5550687	28848596	RT	2	performed and analyzed the biochemical, physiological, morphological, and yield traits	performed and analyzed the biochemical, physiological, morphological, and yield traits	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5550687	28848596	SC	2	as principal investigator, provided conceptual and technical guidance for all aspects	as principal investigator, provided conceptual and technical guidance for all aspects	Conceived and designed the experiments	Conceptualization|Funding acquisition|Supervision	YES
5550687	28848596	SY	2	as principal investigator, provided conceptual and technical guidance for all aspects	as principal investigator, provided conceptual and technical guidance for all aspects	Conceived and designed the experiments	Conceptualization|Funding acquisition|Supervision	YES
5550687	28848596	TS	2	performed and analyzed the biochemical, physiological, morphological, and yield traits	performed and analyzed the biochemical, physiological, morphological, and yield traits	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6025281	29789461	I.H.	2	led on the writing of the paper and correcting all versions of the paper and contributed to data analysis	led on the writing of the paper and correcting all versions of the paper and contributed to data analysis	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
6025281	29789461	R.K.	2	contributed to the project administration, writing of the paper, reviewing and commenting in detail on all versions, in addition to data analysis	contributed to the project administration, writing of the paper, reviewing and commenting in detail on all versions, in addition to data analysis	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Project administration|Resources|Writing - Original Draft|Writing - Review & Editing	YES
6025281	29789461	R.S.	2	facilitated data collection and contributed to the reviewing of the paper and project administration	facilitated data collection and contributed to the reviewing of the paper and project administration	Performed the experiments|Wrote the paper	Investigation|Project administration|Writing - Review & Editing	YES
6025281	29789461	Y.H.	2	contributed to data collection, data analysis and literature search	contributed to data collection, data analysis and literature search	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4488079	26167494	Clare Gilbert	2	conceptualized and designed the study, drafted the initial paper, and critically reviewed and approved the final paper as submitted	conceptualized and designed the study, drafted the initial paper, and critically reviewed and approved the final paper as submitted	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
4873547	27197795	KM	2	both contributed to the preparation of the manuscript	both contributed to the preparation of the manuscript	Wrote the paper	Writing - Original Draft	YES
4873547	27197795	MW	2	both contributed to the preparation of the manuscript	both contributed to the preparation of the manuscript	Wrote the paper	Writing - Original Draft	YES
4198805	25196202	JA	2	as directors and project leaders, had devised and wrote the proposal for obtaining the grant|wrote the manuscript and had the final responsibility for the decision to submit the manuscript for publication	as directors and project leaders, had devised and wrote the proposal for obtaining the grant	Conceived and designed the experiments|Wrote the paper	Conceptualization|Supervision|Writing - Original Draft	YES
4198805	25196202	JA	2	as directors and project leaders, had devised and wrote the proposal for obtaining the grant|wrote the manuscript and had the final responsibility for the decision to submit the manuscript for publication	wrote the manuscript and had the final responsibility for the decision to submit the manuscript for publication	Wrote the paper	Writing - Original Draft	YES
5307646	28193162	All authors	2	carefully checked and approved this version of the manuscript	carefully checked and approved this version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5307646	28193162	CZ	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5307646	28193162	FZ	2	aided in performing the experiments	aided in performing the experiments	Performed the experiments	Investigation	YES
5307646	28193162	GY	2	aided in performing the experiments	aided in performing the experiments	Performed the experiments	Investigation	YES
5307646	28193162	JB	2	performed the experiments, analyzed the data, and drafted the manuscript	performed the experiments, analyzed the data, and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5307646	28193162	LQ	2	performed the experiments, analyzed the data, and drafted the manuscript	performed the experiments, analyzed the data, and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5307646	28193162	LZ	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5307646	28193162	PW	2	assisted with bioinformatic analysis and aided in writing the manuscript	assisted with bioinformatic analysis and aided in writing the manuscript	Wrote the paper	Formal analysis|Writing - Original Draft	YES
5307646	28193162	SY	2	aided in performing the experiments	aided in performing the experiments	Performed the experiments	Investigation	YES
5307646	28193162	WD	2	assisted with bioinformatic analysis and aided in writing the manuscript	assisted with bioinformatic analysis and aided in writing the manuscript	Wrote the paper	Formal analysis|Writing - Original Draft	YES
5307646	28193162	YW	2	performed the experiments, analyzed the data, and drafted the manuscript	performed the experiments, analyzed the data, and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4879178	27221666	AS	2	provided legal analysis and guidance on the relevance of international rights conventions	provided legal analysis and guidance on the relevance of international rights conventions	-	Supervision	YES
4879178	27221666	All authors	2	reviewed and approved the manuscript	reviewed and approved the manuscript	Wrote the paper	Writing - Review & Editing	YES
4879178	27221666	ED	2	led selection of the cases and obtained further details from frontline staff	led selection of the cases and obtained further details from frontline staff	-	-	NO
4405576	25897750	AA	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405576	25897750	AA	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405576	25897750	AA	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405576	25897750	AA	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405576	25897750	AR	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405576	25897750	AR	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405576	25897750	AR	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405576	25897750	AR	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405576	25897750	FJF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405576	25897750	FJF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405576	25897750	FJF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405576	25897750	FJF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405576	25897750	FJF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405576	25897750	JJB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405576	25897750	JJB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405576	25897750	JJB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405576	25897750	JJB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405576	25897750	MB	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4405576	25897750	MB	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405576	25897750	MC	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405576	25897750	MCV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405576	25897750	MCV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405576	25897750	MCV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405576	25897750	MCV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405576	25897750	MCV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405576	25897750	MLE	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405576	25897750	MLE	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405576	25897750	MLE	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405576	25897750	MLE	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405576	25897750	MS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4405576	25897750	MS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4405576	25897750	MS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405576	25897750	WS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4405576	25897750	WS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4405576	25897750	WS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5550689	28848573	GL	2	conceived the research, designed experiments, analyzed the data and wrote the manuscript|carried out field experiments	conceived the research, designed experiments, analyzed the data and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
5550689	28848573	GL	2	conceived the research, designed experiments, analyzed the data and wrote the manuscript|carried out field experiments	carried out field experiments	Performed the experiments	Investigation	YES
5550689	28848573	JH	2	gave valuable suggestions during the whole field and laboratory experiments	gave valuable suggestions during the whole field and laboratory experiments	Performed the experiments	Investigation	YES
5550689	28848573	JP	2	selected the three lines of rice	selected the three lines of rice	-	-	NO
5550689	28848573	KC	2	conceived the research, designed experiments, analyzed the data and wrote the manuscript	conceived the research, designed experiments, analyzed the data and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
5550689	28848573	LN	2	gave valuable suggestions during the whole field and laboratory experiments	gave valuable suggestions during the whole field and laboratory experiments	Performed the experiments	Investigation	YES
5550689	28848573	MY	2	assisted in both sampling and measurements in the field	assisted in both sampling and measurements in the field	Performed the experiments	Investigation	YES
5550689	28848573	PM	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5550689	28848573	QH	2	assisted in physiological determination in the laboratory	assisted in physiological determination in the laboratory	-	-	NO
5550689	28848573	SP	2	gave valuable suggestions during the whole field and laboratory experiments	gave valuable suggestions during the whole field and laboratory experiments	Performed the experiments	Investigation	YES
5550689	28848573	WW	2	assisted in physiological determination in the laboratory	assisted in physiological determination in the laboratory	-	-	NO
5485555	28702183	All authors	2	have more or less contributed to study design, data collection, data analysis and writing	have more or less contributed to study design, data collection, data analysis and writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources	YES
6025336	29724019	All authors	2	were involved in the study concept and design|were involved in the analysis and interpretation of data|participated in critical revision of the manuscript, contributed comments, and approved the final version	were involved in the study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6025336	29724019	All authors	2	were involved in the study concept and design|were involved in the analysis and interpretation of data|participated in critical revision of the manuscript, contributed comments, and approved the final version	were involved in the analysis and interpretation of data	Analyzed the data	Formal analysis	YES
6025336	29724019	All authors	2	were involved in the study concept and design|were involved in the analysis and interpretation of data|participated in critical revision of the manuscript, contributed comments, and approved the final version	participated in critical revision of the manuscript, contributed comments, and approved the final version	Wrote the paper	Writing - Review & Editing	YES
6025336	29724019	M.G.	2	performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
6025336	29724019	S.N.	2	performed the interviews with the patients|wrote the manuscript	performed the interviews with the patients	Performed the experiments	Investigation	YES
6025336	29724019	S.N.	2	performed the interviews with the patients|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4488083	26167483	Emilio Gonzalez Jimenez	2	contributed to design of the study, provided support in the search strategy and selection criteria, wrote the discussion, and made major revisions	contributed to design of the study, provided support in the search strategy and selection criteria, wrote the discussion, and made major revisions	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft|Writing - Review & Editing	YES
4488083	26167483	Jose F. Meneses-Echavez	2	designed the study, applied the search strategy, extracted the data, conducted the pooled analysis, and redacted the major part of the paper	designed the study, applied the search strategy, extracted the data, conducted the pooled analysis, and redacted the major part of the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
4488083	26167483	Robinson Ramirez-Velez	2	applied the search strategy, extracted data, and contributed to preparation of the paper	applied the search strategy, extracted data, and contributed to preparation of the paper	Performed the experiments	Investigation	YES
4405577	25897669	HK	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4405577	25897669	HL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405577	25897669	HL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405577	25897669	HL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405577	25897669	HL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405577	25897669	SEL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405577	25897669	SKH	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405577	25897669	SKH	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405577	25897669	SKH	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405577	25897669	SSB	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4198806	25213372	All authors	2	have contributed to the interpretation of findings and writing of the manuscript	have contributed to the interpretation of findings and writing of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4198806	25213372	Linda Reppe	2	organised the practical arrangements of the study and collected data|have performed the statistical analysis	organised the practical arrangements of the study and collected data	Performed the experiments	Investigation	YES
4198806	25213372	Linda Reppe	2	organised the practical arrangements of the study and collected data|have performed the statistical analysis	have performed the statistical analysis	Analyzed the data	Formal analysis	YES
4198806	25213372	Stian Lydersen	2	have performed the statistical analysis	have performed the statistical analysis	Analyzed the data	Formal analysis	YES
5307739	28193182	AG	2	provided the data|edited the manuscript	provided the data	Contributed reagents/materials/analysis tools	Resources	YES
5307739	28193182	AG	2	provided the data|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5307739	28193182	BFV	2	conceived of and designed the experiments, drafted figures, and wrote the first draft of the manuscript|edited the manuscript	conceived of and designed the experiments, drafted figures, and wrote the first draft of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Visualization|Writing - Original Draft	YES
5307739	28193182	BFV	2	conceived of and designed the experiments, drafted figures, and wrote the first draft of the manuscript|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5307739	28193182	VA	2	conceived of and designed the experiments, drafted figures, and wrote the first draft of the manuscript|performed the analysis and drafted tables|edited the manuscript	conceived of and designed the experiments, drafted figures, and wrote the first draft of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Visualization|Writing - Original Draft	YES
5307739	28193182	VA	2	conceived of and designed the experiments, drafted figures, and wrote the first draft of the manuscript|performed the analysis and drafted tables|edited the manuscript	performed the analysis and drafted tables	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5307739	28193182	VA	2	conceived of and designed the experiments, drafted figures, and wrote the first draft of the manuscript|performed the analysis and drafted tables|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5487299	28702184	Dr Khajehahmadi	1	Pathologist|Corresponded	Pathologist	Performed the experiments	Investigation	YES
5487299	28702184	Dr Khajehahmadi	1	Pathologist|Corresponded	Corresponded	-	-	NO
5487299	28702184	Dr Rahpeyma	1	Study concept or design|Data collection|Writing the paper|Surgeon	Study concept or design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5487299	28702184	Dr Rahpeyma	1	Study concept or design|Data collection|Writing the paper|Surgeon	Data collection	Performed the experiments	Investigation	YES
5487299	28702184	Dr Rahpeyma	1	Study concept or design|Data collection|Writing the paper|Surgeon	Writing the paper	Wrote the paper	Writing - Original Draft	YES
5487299	28702184	Dr Rahpeyma	1	Study concept or design|Data collection|Writing the paper|Surgeon	Surgeon	-	-	NO
4882399	27231099	ADL	2	conducted sequence and statistical analysis	conducted sequence and statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4882399	27231099	All authors	2	read, critically revised and approved the final manuscript	read, critically revised and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4882399	27231099	EK	2	enrolled patients	enrolled patients	Performed the experiments	Investigation	YES
4882399	27231099	JH	2	conducted sequence and statistical analysis	conducted sequence and statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4882399	27231099	KB	2	conducted sequence and statistical analysis|wrote the first draft of the manuscript and worked with co-authors to finalize the writing	conducted sequence and statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4882399	27231099	KB	2	conducted sequence and statistical analysis|wrote the first draft of the manuscript and worked with co-authors to finalize the writing	wrote the first draft of the manuscript and worked with co-authors to finalize the writing	Performed the experiments|Wrote the paper	Writing - Original Draft	YES
4882399	27231099	LD	2	designed the study protocol|supervised study procedures	designed the study protocol	Conceived and designed the experiments	Methodology	YES
4882399	27231099	LD	2	designed the study protocol|supervised study procedures	supervised study procedures	Performed the experiments	Investigation|Supervision	YES
4882399	27231099	MB	2	conducted laboratory assays|conducted sequence and statistical analysis	conducted laboratory assays	Performed the experiments	Investigation	YES
4882399	27231099	MB	2	conducted laboratory assays|conducted sequence and statistical analysis	conducted sequence and statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4882399	27231099	MC	2	conducted laboratory assays|conducted sequence and statistical analysis	conducted laboratory assays	Performed the experiments	Investigation	YES
4882399	27231099	MC	2	conducted laboratory assays|conducted sequence and statistical analysis	conducted sequence and statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4882399	27231099	MO	2	conducted laboratory assays	conducted laboratory assays	Performed the experiments	Investigation	YES
4882399	27231099	MR	2	conducted laboratory assays	conducted laboratory assays	Performed the experiments	Investigation	YES
4882399	27231099	RK	2	conceived the study and was responsible for all its aspects|designed the study protocol|conducted sequence and statistical analysis|wrote the first draft of the manuscript and worked with co-authors to finalize the writing	conceived the study and was responsible for all its aspects	Conceived and designed the experiments	Conceptualization	YES
4882399	27231099	RK	2	conceived the study and was responsible for all its aspects|designed the study protocol|conducted sequence and statistical analysis|wrote the first draft of the manuscript and worked with co-authors to finalize the writing	designed the study protocol	Conceived and designed the experiments	Methodology	YES
4882399	27231099	RK	2	conceived the study and was responsible for all its aspects|designed the study protocol|conducted sequence and statistical analysis|wrote the first draft of the manuscript and worked with co-authors to finalize the writing	conducted sequence and statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4882399	27231099	RK	2	conceived the study and was responsible for all its aspects|designed the study protocol|conducted sequence and statistical analysis|wrote the first draft of the manuscript and worked with co-authors to finalize the writing	wrote the first draft of the manuscript and worked with co-authors to finalize the writing	Performed the experiments|Wrote the paper	Writing - Original Draft	YES
4882399	27231099	WI	2	supervised study procedures	supervised study procedures	Performed the experiments	Investigation|Supervision	YES
5412580	28507686	E.C.	2	analyzed the magnetic data	analyzed the magnetic data	Analyzed the data	Formal analysis	YES
5412580	28507686	F.R.	2	carried out measurements and analysis of adsorption isotherms	carried out measurements and analysis of adsorption isotherms	Performed the experiments	Investigation	YES
5412580	28507686	G.M.E.	2	contributed to solution and refinement of the structures from single crystal data|collected the synchrotron x-ray powder diffraction data|analyzed the powder diffraction data|analyzed the magnetic data|conceived the research and prepared the manuscript	contributed to solution and refinement of the structures from single crystal data	Contributed reagents/materials/analysis tools	Resources	YES
5412580	28507686	G.M.E.	2	contributed to solution and refinement of the structures from single crystal data|collected the synchrotron x-ray powder diffraction data|analyzed the powder diffraction data|analyzed the magnetic data|conceived the research and prepared the manuscript	collected the synchrotron x-ray powder diffraction data	Performed the experiments	Investigation	YES
5412580	28507686	G.M.E.	2	contributed to solution and refinement of the structures from single crystal data|collected the synchrotron x-ray powder diffraction data|analyzed the powder diffraction data|analyzed the magnetic data|conceived the research and prepared the manuscript	analyzed the powder diffraction data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5412580	28507686	G.M.E.	2	contributed to solution and refinement of the structures from single crystal data|collected the synchrotron x-ray powder diffraction data|analyzed the powder diffraction data|analyzed the magnetic data|conceived the research and prepared the manuscript	analyzed the magnetic data	Analyzed the data	Formal analysis	YES
5412580	28507686	G.M.E.	2	contributed to solution and refinement of the structures from single crystal data|collected the synchrotron x-ray powder diffraction data|analyzed the powder diffraction data|analyzed the magnetic data|conceived the research and prepared the manuscript	conceived the research and prepared the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5412580	28507686	G.S.	2	performed the molecular dynamics calculations	performed the molecular dynamics calculations	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5412580	28507686	I.J.V.Y.	2	collected the synchrotron x-ray powder diffraction data|analyzed the powder diffraction data	collected the synchrotron x-ray powder diffraction data	Performed the experiments	Investigation	YES
5412580	28507686	I.J.V.Y.	2	collected the synchrotron x-ray powder diffraction data|analyzed the powder diffraction data	analyzed the powder diffraction data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5412580	28507686	J.L.J.	2	collected the synchrotron x-ray powder diffraction data	collected the synchrotron x-ray powder diffraction data	Performed the experiments	Investigation	YES
5412580	28507686	M.G.M.	2	synthesized the materials|contributed to solution and refinement of the structures from single crystal data	synthesized the materials	Performed the experiments	Investigation	YES
5412580	28507686	M.G.M.	2	synthesized the materials|contributed to solution and refinement of the structures from single crystal data	contributed to solution and refinement of the structures from single crystal data	Contributed reagents/materials/analysis tools	Resources	YES
5412580	28507686	M.P.	2	carried out measurements and analysis of adsorption isotherms	carried out measurements and analysis of adsorption isotherms	Performed the experiments	Investigation	YES
5412580	28507686	N.C.G.	2	synthesized the materials|collected the synchrotron x-ray powder diffraction data	synthesized the materials	Performed the experiments	Investigation	YES
5412580	28507686	N.C.G.	2	synthesized the materials|collected the synchrotron x-ray powder diffraction data	collected the synchrotron x-ray powder diffraction data	Performed the experiments	Investigation	YES
5412580	28507686	S.V.	2	carried out measurements and analysis of adsorption isotherms	carried out measurements and analysis of adsorption isotherms	Performed the experiments	Investigation	YES
5412580	28507686	all authors	2	made comments on the manuscript	made comments on the manuscript	-	-	NO
5550694	28848571	AD	2	wrote the article, revised the text based on feedback from the co-authors, and prepared the illustrations	wrote the article, revised the text based on feedback from the co-authors, and prepared the illustrations	Analyzed the data|Wrote the paper	Visualization|Writing - Original Draft|Writing - Review & Editing	YES
5550694	28848571	AS	2	helped prepare the figures	helped prepare the figures	-	Visualization	YES
5550694	28848571	HK	2	conceptualized the overall structure of the review article and critically edited it	conceptualized the overall structure of the review article and critically edited it	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5550694	28848571	MT	2	helped prepare the figures	helped prepare the figures	-	Visualization	YES
5550694	28848571	SP	2	provided editorial suggestions regarding the article	provided editorial suggestions regarding the article	Wrote the paper	Writing - Review & Editing	YES
5550694	28848571	YK	2	conceptualized the overall structure of the review article and critically edited it	conceptualized the overall structure of the review article and critically edited it	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
4488085	26167490	Wan-Jhen Wang	2	contributed equally to this work	contributed equally to this work	-	-	NO
4488085	26167490	Yu-Sheng Wu	2	contributed equally to this work	contributed equally to this work	-	-	NO
5489712	28702180	All authors	2	contributed equally to the manuscript	contributed equally to the manuscript	-	-	NO
4405578	25898139	AMC	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405578	25898139	AMC	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405578	25898139	AMC	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405578	25898139	AMC	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405578	25898139	ET	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405578	25898139	ET	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405578	25898139	ET	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405578	25898139	ET	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405578	25898139	JF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405578	25898139	JF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405578	25898139	JF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405578	25898139	JF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405578	25898139	MHH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405578	25898139	MHH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405578	25898139	MHH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405578	25898139	SM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4405578	25898139	SM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405578	25898139	WS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405578	25898139	WS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405578	25898139	WS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3606767	23533346	B. Gao	2	both contributed equally to this paper	both contributed equally to this paper	-	-	NO
3606767	23533346	H. Jiang	2	both contributed equally to this paper	both contributed equally to this paper	-	-	NO
4226930	25291992	Andrzej Kiejna	2	participated in data analysis and consulted methodology of this study	participated in data analysis and consulted methodology of this study	Performed the experiments|Analyzed the data	Formal analysis|Methodology	YES
4226930	25291992	Blazej Misiak	2	was involved in the recruitment of patients, data analysis and preparation of the manuscript	was involved in the recruitment of patients, data analysis and preparation of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4226930	25291992	Dorota Frydecka	2	was involved in data analysis and preparation of the manuscript	was involved in data analysis and preparation of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4226930	25291992	Lukasz Laczmanski	2	were involved in data analysis	were involved in data analysis	Analyzed the data	Formal analysis	YES
4226930	25291992	Ryszard Slezak	2	were involved in data analysis	were involved in data analysis	Analyzed the data	Formal analysis	YES
4405579	25897662	HSP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405579	25897662	JLB	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4405579	25897662	JMJ	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4405579	25897662	JMK	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4405579	25897662	JSK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405579	25897662	JSK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405579	25897662	JSK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405579	25897662	JWL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405579	25897662	JWL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405579	25897662	JWL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405579	25897662	JWL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405579	25897662	RSH	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4405579	25897662	SAP	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4405579	25897662	SAP	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4405579	25897662	SHR	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4405579	25897662	SHR	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4405579	25897662	WKH	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4405579	25897662	WM	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4405579	25897662	WM	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5307786	28193177	BA	1	Conception and design of the study|Gene annotation|Data analysis and contribution to writing the manuscript|Writing of the first manuscript draft	Conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5307786	28193177	BA	1	Conception and design of the study|Gene annotation|Data analysis and contribution to writing the manuscript|Writing of the first manuscript draft	Gene annotation	Analyzed the data	Data curation|Formal analysis	YES
5307786	28193177	BA	1	Conception and design of the study|Gene annotation|Data analysis and contribution to writing the manuscript|Writing of the first manuscript draft	Data analysis and contribution to writing the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5307786	28193177	BA	1	Conception and design of the study|Gene annotation|Data analysis and contribution to writing the manuscript|Writing of the first manuscript draft	Writing of the first manuscript draft	Wrote the paper	Writing - Original Draft	YES
5307786	28193177	CJS	1	Data analysis and contribution to writing the manuscript	Data analysis and contribution to writing the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5307786	28193177	FL	1	Gene annotation|Data analysis and contribution to writing the manuscript	Gene annotation	Analyzed the data	Data curation|Formal analysis	YES
5307786	28193177	FL	1	Gene annotation|Data analysis and contribution to writing the manuscript	Data analysis and contribution to writing the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5307786	28193177	JMCR	1	Conception and design of the study|Gene annotation|Data analysis and contribution to writing the manuscript	Conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5307786	28193177	JMCR	1	Conception and design of the study|Gene annotation|Data analysis and contribution to writing the manuscript	Gene annotation	Analyzed the data	Data curation|Formal analysis	YES
5307786	28193177	JMCR	1	Conception and design of the study|Gene annotation|Data analysis and contribution to writing the manuscript	Data analysis and contribution to writing the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5550695	28848569	AL-H	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5550695	28848569	BE	2	provided study materials and critical revision of the manuscript	provided study materials and critical revision of the manuscript	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Review & Editing	YES
5550695	28848569	DM	2	designed most experiments and wrote the manuscript	designed most experiments and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5550695	28848569	FB	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5550695	28848569	RB	2	carried out the experiments|designed most experiments and wrote the manuscript	carried out the experiments	Performed the experiments	Investigation	YES
5550695	28848569	RB	2	carried out the experiments|designed most experiments and wrote the manuscript	designed most experiments and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5550695	28848569	SD	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
4884676	27237131	All authors	2	contributed to the conduct of the study, the interpretation of the results, and the writing of the article	contributed to the conduct of the study, the interpretation of the results, and the writing of the article	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4884676	27237131	LJA-R	2	conceived the study, led the design of the study, and drafted the article	conceived the study, led the design of the study, and drafted the article	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
4884676	27237131	MH	2	conducted the search and data synthesis and wrote the first draft of the paper	conducted the search and data synthesis and wrote the first draft of the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5491485	28702185	All authors	2	gave final approval of the version to be published	gave final approval of the version to be published	-	-	NO
5491485	28702185	DM	2	undertook the study	undertook the study	Performed the experiments	Investigation	YES
5491485	28702185	DMB	2	undertook the study|drafted the manuscript	undertook the study	Performed the experiments	Investigation	YES
5491485	28702185	DMB	2	undertook the study|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5491485	28702185	JH	2	revised it critically	revised it critically	Wrote the paper	Writing - Review & Editing	YES
5491485	28702185	MH	2	revised it critically	revised it critically	Wrote the paper	Writing - Review & Editing	YES
5491485	28702185	OT	2	revised it critically	revised it critically	Wrote the paper	Writing - Review & Editing	YES
5491485	28702185	RC	2	revised it critically	revised it critically	Wrote the paper	Writing - Review & Editing	YES
5491485	28702185	SEL	2	revised it critically	revised it critically	Wrote the paper	Writing - Review & Editing	YES
5491485	28702185	SL	2	undertook the study	undertook the study	Performed the experiments	Investigation	YES
6025360	29843357	C.T.	2	analyzed and interpreted the data|revised the manuscript	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
6025360	29843357	C.T.	2	analyzed and interpreted the data|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
6025360	29843357	H.B.O.M.	2	contributed to conception of the study design|included the patients and collected the data|revised the manuscript	contributed to conception of the study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6025360	29843357	H.B.O.M.	2	contributed to conception of the study design|included the patients and collected the data|revised the manuscript	included the patients and collected the data	Performed the experiments	Investigation	YES
6025360	29843357	H.B.O.M.	2	contributed to conception of the study design|included the patients and collected the data|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
6025360	29843357	J.P.	2	analyzed and interpreted the data|revised the manuscript	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
6025360	29843357	J.P.	2	analyzed and interpreted the data|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
6025360	29843357	L.J.K.	2	contributed to conception of the study design|revised the manuscript	contributed to conception of the study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6025360	29843357	L.J.K.	2	contributed to conception of the study design|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
6025360	29843357	M.B.H.	2	contributed to conception of the study design|included the patients and collected the data|analyzed and interpreted the data|drafted the manuscript	contributed to conception of the study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6025360	29843357	M.B.H.	2	contributed to conception of the study design|included the patients and collected the data|analyzed and interpreted the data|drafted the manuscript	included the patients and collected the data	Performed the experiments	Investigation	YES
6025360	29843357	M.B.H.	2	contributed to conception of the study design|included the patients and collected the data|analyzed and interpreted the data|drafted the manuscript	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
6025360	29843357	M.B.H.	2	contributed to conception of the study design|included the patients and collected the data|analyzed and interpreted the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
6025360	29843357	O.A.	2	contributed to conception of the study design|analyzed and interpreted the data|revised the manuscript	contributed to conception of the study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6025360	29843357	O.A.	2	contributed to conception of the study design|analyzed and interpreted the data|revised the manuscript	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
6025360	29843357	O.A.	2	contributed to conception of the study design|analyzed and interpreted the data|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
6025360	29843357	S.L.A.	2	contributed to conception of the study design|revised the manuscript	contributed to conception of the study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6025360	29843357	S.L.A.	2	contributed to conception of the study design|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
6025360	29843357	T.H.H.	2	analyzed and interpreted the data|revised the manuscript	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
6025360	29843357	T.H.H.	2	analyzed and interpreted the data|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4333233	25567216	Anders Koldestam	2	contributed in acquisition of data, critical revision of the manuscript for important intellectual content, and final approval of the manuscript	contributed in acquisition of data, critical revision of the manuscript for important intellectual content, and final approval of the manuscript	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Resources|Writing - Review & Editing	YES
4333233	25567216	Bjorn Belfrage	2	contributed in acquisition of data, analysis and interpretation of data, drafting of the manuscript, critical revision of the manuscript for important intellectual content, and final approval of the manuscript	contributed in acquisition of data, analysis and interpretation of data, drafting of the manuscript, critical revision of the manuscript for important intellectual content, and final approval of the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
4333233	25567216	Christina Sjoberg	2	contributed in acquisition of data, critical revision of the manuscript for important intellectual content, and final approval of the manuscript	contributed in acquisition of data, critical revision of the manuscript for important intellectual content, and final approval of the manuscript	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Resources|Writing - Review & Editing	YES
4333233	25567216	M Wallerstedt	2	contributed in conception and design, analysis and interpretation of data, drafting of the manuscript, critical revision of the manuscript for important intellectual content, and final approval of the manuscript	contributed in conception and design, analysis and interpretation of data, drafting of the manuscript, critical revision of the manuscript for important intellectual content, and final approval of the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Resources|Writing - Original Draft|Writing - Review & Editing	YES
4405580	25897963	BMN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405580	25897963	BMN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405580	25897963	BMN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405580	25897963	BMN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405580	25897963	BMN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405580	25897963	CM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405580	25897963	CM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405580	25897963	CM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405580	25897963	JB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405580	25897963	JB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405580	25897963	JB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5491486	28702186	Eugenio Grignaffini	2	data collections	data collections	Performed the experiments	Investigation	YES
5491486	28702186	Grieco Michele Pio	2	data collections	data collections	Performed the experiments	Investigation	YES
5491486	28702186	Raposio Edoardo	2	study design	study design	Conceived and designed the experiments	Methodology	YES
5491486	28702186	Simonacci Francesco	2	data collections	data collections	Performed the experiments	Investigation	YES
5550696	28848584	AF	2	designed, planned and performed the experiments and analyzed the data	designed, planned and performed the experiments and analyzed the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation|Methodology	YES
5550696	28848584	AS	2	designed, planned and performed the experiments and analyzed the data	designed, planned and performed the experiments and analyzed the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation|Methodology	YES
5550696	28848584	BZ	2	designed, planned and performed the experiments and analyzed the data	designed, planned and performed the experiments and analyzed the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation|Methodology	YES
5550696	28848584	MH	2	supervised the project and wrote the manuscript	supervised the project and wrote the manuscript	Wrote the paper	Supervision|Writing - Original Draft	YES
5550696	28848584	MP	2	designed, planned and performed the experiments and analyzed the data	designed, planned and performed the experiments and analyzed the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation|Methodology	YES
5550696	28848584	SH	2	designed, planned and performed the experiments and analyzed the data	designed, planned and performed the experiments and analyzed the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation|Methodology	YES
6025366	29735914	A.Ab	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6025366	29735914	A.Ad	PLoS52	analyzed the data collected from the online forms	analyzed the data collected from the online forms	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6025366	29735914	N.A.	PLoS52	digitalized the questionnaire	digitalized the questionnaire	-	-	NO
6025366	29735914	N.S.	PLoS52	provided input regarding the design|analyzed the data collected from the online forms	provided input regarding the design	Conceived and designed the experiments	-	YES
6025366	29735914	N.S.	PLoS52	provided input regarding the design|analyzed the data collected from the online forms	analyzed the data collected from the online forms	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5307792	28193179	BM	2	performed the microarray analysis	performed the microarray analysis	Performed the experiments	Investigation	YES
5307792	28193179	GLP	2	designed and managed the study, and prepared the manuscript	designed and managed the study, and prepared the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft	YES
5307792	28193179	KM	2	contributed to the preparation of the manuscript	contributed to the preparation of the manuscript	Wrote the paper	Writing - Original Draft	YES
5307792	28193179	PC	2	performed statistical analyses	performed statistical analyses	Analyzed the data	Formal analysis	YES
5307792	28193179	SA	2	isolated pbmcs from the blood samples of study subjects, enumerated select subtypes	isolated pbmcs from the blood samples of study subjects, enumerated select subtypes	Performed the experiments	Investigation	YES
4887458	27247202	Ariane van der Straten	2	is the protocol chair of the voice-d trial and contributed to the analysis and writing of this manuscript	is the protocol chair of the voice-d trial and contributed to the analysis and writing of this manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4887458	27247202	Ellen Luecke	2	led the analysis and writing of this manuscript	led the analysis and writing of this manuscript	Wrote the paper	Writing - Original Draft	YES
4887458	27247202	Helen Cheng	2	conducted the quantitative analysis	conducted the quantitative analysis	Performed the experiments	Investigation	YES
4887458	27247202	Imelda Mudekunye-Mahaka	2	reviewed and contributed towards the qualitative analysis and manuscript	reviewed and contributed towards the qualitative analysis and manuscript	Wrote the paper	Writing - Review & Editing	YES
4887458	27247202	Kubashni Woeber	2	reviewed and contributed towards the qualitative analysis and manuscript	reviewed and contributed towards the qualitative analysis and manuscript	Wrote the paper	Writing - Review & Editing	YES
4887458	27247202	Teopista Nakyanzi	2	reviewed and contributed towards the qualitative analysis and manuscript	reviewed and contributed towards the qualitative analysis and manuscript	Wrote the paper	Writing - Review & Editing	YES
3270501	22315692	A. Reeler	2	contributed to paper development and study design	contributed to paper development and study design	Conceived and designed the experiments	Methodology	YES
3270501	22315692	C. Hobden	2	authored sections of the paper and led background reviews	authored sections of the paper and led background reviews	Wrote the paper	Writing - Original Draft	YES
3270501	22315692	S. Bogale	2	participated in study design and implementation, and protocol development	participated in study design and implementation, and protocol development	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3270501	22315692	T. D. Dye	2	supervised development and implementation of the study and was the principal author of this paper	supervised development and implementation of the study and was the principal author of this paper	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Original Draft	YES
3270501	22315692	T. Deressa	2	contributed to study design, supervised data collection, and contributed to authoring the paper	contributed to study design, supervised data collection, and contributed to authoring the paper	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Methodology|Resources|Supervision|Writing - Original Draft	YES
3270501	22315692	Y. Tilahun	2	contributed to the study design, supervised data collection, and contributed to authoring the paper	contributed to the study design, supervised data collection, and contributed to authoring the paper	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Methodology|Resources|Supervision|Writing - Original Draft	YES
5491488	28702187	Bertozzi Nicolo	2	data collections	data collections	Performed the experiments	Investigation	YES
5491488	28702187	Eugenio Grignaffini	2	data collections	data collections	Performed the experiments	Investigation	YES
5491488	28702187	Grieco Michele Pio	2	data collections	data collections	Performed the experiments	Investigation	YES
5491488	28702187	Raposio Edoardo	2	study design	study design	Conceived and designed the experiments	Methodology	YES
4405581	25897519	FAL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405581	25897519	FAL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405581	25897519	FAL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405581	25897519	FAL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405581	25897519	PF	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405581	25897519	PF	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405581	25897519	PF	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405581	25897519	RR	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405581	25897519	RR	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405581	25897519	RR	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6025379	29614725	A.S.	PLoS52	collected the data|analyzed the data|wrote the paper	collected the data	Performed the experiments	Investigation	YES
6025379	29614725	A.S.	PLoS52	collected the data|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
6025379	29614725	A.S.	PLoS52	collected the data|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6025379	29614725	All the authors	PLoS52	finalized the final version of the manuscript	finalized the final version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
6025379	29614725	H.S.	PLoS52	collected the data	collected the data	Performed the experiments	Investigation	YES
6025379	29614725	M.M.R.	PLoS52	collected the data	collected the data	Performed the experiments	Investigation	YES
6025379	29614725	S.A.	PLoS52	conceived and designed the study|analyzed the data	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6025379	29614725	S.A.	PLoS52	conceived and designed the study|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
6025379	29614725	S.J.	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6025379	29614725	S.Q.J.	PLoS52	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4356885	25666030	CC	2	planned and designed this study|performed data linkage and analysis|critically reviewed and approved the final manuscript	planned and designed this study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4356885	25666030	CC	2	planned and designed this study|performed data linkage and analysis|critically reviewed and approved the final manuscript	performed data linkage and analysis	Analyzed the data	Formal analysis	YES
4356885	25666030	CC	2	planned and designed this study|performed data linkage and analysis|critically reviewed and approved the final manuscript	critically reviewed and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4356885	25666030	FM	2	planned and designed this study|performed data linkage and analysis	planned and designed this study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4356885	25666030	FM	2	planned and designed this study|performed data linkage and analysis	performed data linkage and analysis	Analyzed the data	Formal analysis	YES
4356885	25666030	KB	2	planned and designed this study|critically reviewed and approved the final manuscript	planned and designed this study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4356885	25666030	KB	2	planned and designed this study|critically reviewed and approved the final manuscript	critically reviewed and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4356885	25666030	RAK	2	critically reviewed and approved the final manuscript	critically reviewed and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4356885	25666030	TF	2	planned and designed this study|critically reviewed and approved the final manuscript	planned and designed this study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4356885	25666030	TF	2	planned and designed this study|critically reviewed and approved the final manuscript	critically reviewed and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5307951	28193158	AZ	2	participated in the projects design and coordination and critically revised the manuscript	participated in the projects design and coordination and critically revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Review & Editing	YES
5307951	28193158	LZ	2	contributed to data interpretation and manuscript drafting	contributed to data interpretation and manuscript drafting	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5307951	28193158	NT	2	contributed to data interpretation and manuscript drafting	contributed to data interpretation and manuscript drafting	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5307951	28193158	RP	2	participated in the projects design and coordination and critically revised the manuscript	participated in the projects design and coordination and critically revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Review & Editing	YES
5307951	28193158	SV	2	contributed to data interpretation and manuscript drafting	contributed to data interpretation and manuscript drafting	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5307951	28193158	ZV	2	participated in the projects design and coordination and critically revised the manuscript	participated in the projects design and coordination and critically revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Review & Editing	YES
5550703	28848580	SE	2	conceived the idea and wrote the manuscript	conceived the idea and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5550703	28848580	SL	2	conceived the idea and wrote the manuscript	conceived the idea and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4891946	27258430	All authors	2	contributed to interpretation of the analysis results and commented on drafts of the manuscript	contributed to interpretation of the analysis results and commented on drafts of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4891946	27258430	CI	2	developed the concept and discussed the analysis plan	developed the concept and discussed the analysis plan	Conceived and designed the experiments	Conceptualization	YES
4891946	27258430	KEF	2	developed the concept and discussed the analysis plan|conducted the statistical analysis	developed the concept and discussed the analysis plan	Conceived and designed the experiments	Conceptualization	YES
4891946	27258430	KEF	2	developed the concept and discussed the analysis plan|conducted the statistical analysis	conducted the statistical analysis	Analyzed the data	Formal analysis	YES
4891946	27258430	MP	2	developed the concept and discussed the analysis plan|conducted the statistical analysis|drafted the manuscript	developed the concept and discussed the analysis plan	Conceived and designed the experiments	Conceptualization	YES
4891946	27258430	MP	2	developed the concept and discussed the analysis plan|conducted the statistical analysis|drafted the manuscript	conducted the statistical analysis	Analyzed the data	Formal analysis	YES
4891946	27258430	MP	2	developed the concept and discussed the analysis plan|conducted the statistical analysis|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4891946	27258430	RDS	2	developed the concept and discussed the analysis plan	developed the concept and discussed the analysis plan	Conceived and designed the experiments	Conceptualization	YES
6025429	29751503	M.C.T.	2	conceived and designed the study, analyzed the data, and drafted preliminary findings|wrote and revised the paper	conceived and designed the study, analyzed the data, and drafted preliminary findings	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
6025429	29751503	M.C.T.	2	conceived and designed the study, analyzed the data, and drafted preliminary findings|wrote and revised the paper	wrote and revised the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6025429	29751503	P.J.H.	2	wrote and revised the paper	wrote and revised the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5493815	28702188	All authors	2	contributed equally to the manuscript	contributed equally to the manuscript	-	-	NO
4405582	25898254	QY	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405582	25898254	QY	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405582	25898254	QY	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405582	25898254	QZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405582	25898254	WW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405582	25898254	XH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405582	25898254	Xiaoyu Zhu	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405582	25898254	Xiaoyu Zhu Xufen	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405582	25898254	Xiaoyu Zhu Xufen	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405582	25898254	Xiaoyu Zhu Xufen	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405582	25898254	Xufen Zhu	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405582	25898254	YD	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405582	25898254	ZY	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5496485	28702189	Abdul Wadood	2	was involved directly in acquiring data from the patient	was involved directly in acquiring data from the patient	Performed the experiments	Investigation	YES
5496485	28702189	Anila Chughtai	2	have been involved in drafting the manuscript	have been involved in drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
5496485	28702189	Kashif Malik	2	have been involved in drafting the manuscript	have been involved in drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
5496485	28702189	Mahmood Ayyaz Khan	2	has given final approval of the version to be published	has given final approval of the version to be published	-	-	NO
5496485	28702189	Shabbar Hussain Changezi	2	has been involved in revising it critically for important intellectual content	has been involved in revising it critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5496485	28702189	Usman Ismat Butt	2	made substantial contributions to conception and design of data	made substantial contributions to conception and design of data	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceptualization|Resources	YES
5550715	28848578	DQ	2	participated in physiological assays and gene expression assays	participated in physiological assays and gene expression assays	Performed the experiments	Investigation	YES
5550715	28848578	FZ	2	participated in physiological assays and gene expression assays	participated in physiological assays and gene expression assays	Performed the experiments	Investigation	YES
5550715	28848578	GH	2	designed the experiments and wrote the paper	designed the experiments and wrote the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5550715	28848578	GY	2	designed the experiments and wrote the paper	designed the experiments and wrote the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5550715	28848578	JC	2	designed the experiments and wrote the paper	designed the experiments and wrote the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5550715	28848578	KL	2	participated in physiological assays and gene expression assays	participated in physiological assays and gene expression assays	Performed the experiments	Investigation	YES
5550715	28848578	QL	2	helped to perform genetic transformation and partial data analysis	helped to perform genetic transformation and partial data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5550715	28848578	QW	2	designed the experiments and wrote the paper|performed all experiments and analyzed the data	designed the experiments and wrote the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5550715	28848578	QW	2	designed the experiments and wrote the paper|performed all experiments and analyzed the data	performed all experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5550715	28848578	RW	2	participated in physiological assays and gene expression assays	participated in physiological assays and gene expression assays	Performed the experiments	Investigation	YES
5550715	28848578	YH	2	participated in physiological assays and gene expression assays	participated in physiological assays and gene expression assays	Performed the experiments	Investigation	YES
5550715	28848578	YZ	2	participated in physiological assays and gene expression assays	participated in physiological assays and gene expression assays	Performed the experiments	Investigation	YES
4899532	27281790	AJS	2	contributed to the analyses design	contributed to the analyses design	Conceived and designed the experiments|Analyzed the data	Formal analysis	YES
4899532	27281790	AP	2	provided the data, as well as guidance and comments on the analysis	provided the data, as well as guidance and comments on the analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources|Supervision	YES
4899532	27281790	CCK	2	contributed to the model design	contributed to the model design	Conceived and designed the experiments|Performed the experiments	Methodology	YES
4899532	27281790	CJB	2	assisted with coordination of the data collection and project collaboration	assisted with coordination of the data collection and project collaboration	Performed the experiments	Investigation|Project administration	YES
4899532	27281790	DPW	2	contributed to the analyses design	contributed to the analyses design	Conceived and designed the experiments|Analyzed the data	Formal analysis	YES
4899532	27281790	RH	2	provided the data, as well as guidance and comments on the analysis	provided the data, as well as guidance and comments on the analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources|Supervision	YES
4899532	27281790	RMS	2	contributed to the model design	contributed to the model design	Conceived and designed the experiments|Performed the experiments	Methodology	YES
4899532	27281790	SG	2	provided the data, as well as guidance and comments on the analysis	provided the data, as well as guidance and comments on the analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources|Supervision	YES
4899532	27281790	SLK	2	conducted the analyses and prepared the manuscript	conducted the analyses and prepared the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4899532	27281790	TG	2	provided the data, as well as guidance and comments on the analysis	provided the data, as well as guidance and comments on the analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources|Supervision	YES
6025435	30720782	All authors	2	approved the submitted version for publication|declare that they had complete access to the study data that support the publication	approved the submitted version for publication	-	-	NO
6025435	30720782	All authors	2	approved the submitted version for publication|declare that they had complete access to the study data that support the publication	declare that they had complete access to the study data that support the publication	-	-	NO
6025435	30720782	D.V.	2	provided comments for each step of the study and reviewed the manuscript	provided comments for each step of the study and reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
6025435	30720782	H.G.	2	provided comments for each step of the study and reviewed the manuscript	provided comments for each step of the study and reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
6025435	30720782	J-P.G.	2	contributed to the design of the study and needs assessment	contributed to the design of the study and needs assessment	Conceived and designed the experiments	Methodology	YES
6025435	30720782	J.M.	2	contributed to the design of the study and needs assessment	contributed to the design of the study and needs assessment	Conceived and designed the experiments	Methodology	YES
6025435	30720782	L.G.	2	led the intervention mapping process and managed the design of the current intervention	led the intervention mapping process and managed the design of the current intervention	Conceived and designed the experiments	-	YES
6025435	30720782	S.L.	2	led the intervention mapping process and managed the design of the current intervention	led the intervention mapping process and managed the design of the current intervention	Conceived and designed the experiments	-	YES
6025435	30720782	T.S.	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5309984	28196473	AHS	PLoS52	supervised the work	supervised the work	-	Supervision	YES
5309984	28196473	GS	PLoS52	analysed the data|wrote the paper	analysed the data	Analyzed the data	Formal analysis	YES
5309984	28196473	GS	PLoS52	analysed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5309984	28196473	IB	PLoS52	designed the workflows and coordinated implementation|supervised the work	designed the workflows and coordinated implementation	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Project administration	YES
5309984	28196473	IB	PLoS52	designed the workflows and coordinated implementation|supervised the work	supervised the work	-	Supervision	YES
5309984	28196473	JP	PLoS52	supervised the work	supervised the work	-	Supervision	YES
5309984	28196473	KL	PLoS52	developed and optimised the assays and primer sets	developed and optimised the assays and primer sets	Performed the experiments	Investigation	YES
5309984	28196473	PCR	PLoS52	normalisation method	normalisation method	Performed the experiments	-	YES
5309984	28196473	VL	PLoS52	wrote the paper|designed the workflows and coordinated implementation|supervised the work	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5309984	28196473	VL	PLoS52	wrote the paper|designed the workflows and coordinated implementation|supervised the work	designed the workflows and coordinated implementation	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Project administration	YES
5309984	28196473	VL	PLoS52	wrote the paper|designed the workflows and coordinated implementation|supervised the work	supervised the work	-	Supervision	YES
6025481	29671768	L.C.D.	2	designed the study, conducted the focus group interview, analysed the data|carried out the individual interviews|revised as well as approved the submitted version of the manuscript	designed the study, conducted the focus group interview, analysed the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
6025481	29671768	L.C.D.	2	designed the study, conducted the focus group interview, analysed the data|carried out the individual interviews|revised as well as approved the submitted version of the manuscript	carried out the individual interviews	Performed the experiments	Investigation	YES
6025481	29671768	L.C.D.	2	designed the study, conducted the focus group interview, analysed the data|carried out the individual interviews|revised as well as approved the submitted version of the manuscript	revised as well as approved the submitted version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
6025481	29671768	S.K.S.	2	designed the study, conducted the focus group interview, analysed the data|revised as well as approved the submitted version of the manuscript	designed the study, conducted the focus group interview, analysed the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
6025481	29671768	S.K.S.	2	designed the study, conducted the focus group interview, analysed the data|revised as well as approved the submitted version of the manuscript	revised as well as approved the submitted version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4405583	25897751	CSR	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405583	25897751	ED	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405583	25897751	FO	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405583	25897751	JMFR	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405583	25897751	JMFR	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405583	25897751	JMNN	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4405583	25897751	JMNN	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4405583	25897751	MM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405583	25897751	MM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405583	25897751	MM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405583	25897751	MS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405583	25897751	PB	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405583	25897751	SV	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405583	25897751	WR	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4488155	26167495	Geng Guo	2	contributed equally to this work	contributed equally to this work	-	-	NO
4488155	26167495	Liu Yang	2	contributed equally to this work	contributed equally to this work	-	-	NO
5550716	28848577	All authors	2	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5550716	28848577	DT	2	prepared figures	prepared figures	-	Visualization	YES
5550716	28848577	HZ	2	wrote the main manuscript text	wrote the main manuscript text	Wrote the paper	Writing - Original Draft	YES
5550716	28848577	JF	2	designed the overall of this study	designed the overall of this study	Conceived and designed the experiments	Methodology	YES
5550716	28848577	JL	2	prepared the tables	prepared the tables	-	-	NO
5550716	28848577	JS	2	designed the overall of this study	designed the overall of this study	Conceived and designed the experiments	Methodology	YES
5550716	28848577	KC	2	wrote the main manuscript text	wrote the main manuscript text	Wrote the paper	Writing - Original Draft	YES
5550716	28848577	MH	2	prepared figures	prepared figures	-	Visualization	YES
5550716	28848577	MZ	2	wrote the main manuscript text	wrote the main manuscript text	Wrote the paper	Writing - Original Draft	YES
5550716	28848577	QZ	2	wrote the main manuscript text	wrote the main manuscript text	Wrote the paper	Writing - Original Draft	YES
5550716	28848577	XH	2	prepared the tables	prepared the tables	-	-	NO
4493629	26161157	Diego Costa Astur	7	Corresponding author analyse the comparisons between groups and decide the study draw	Corresponding author analyse the comparisons between groups and decide the study draw	-	-	NO
4493629	26161157	Gustavo Borges Gouveia	7	Colect dates after the patients fill the questionaires	Colect dates after the patients fill the questionaires	-	-	NO
4493629	26161157	Gustavo Goncalves Arliani	7	Colect dates after the patients fill the questionaires. Camila Cohen kaleka: Colect dates after the patients fill the questionaires	Colect dates after the patients fill the questionaires. Camila Cohen kaleka: Colect dates after the patients fill the questionaires	-	-	NO
4493629	26161157	Jose Humberto Borges	7	Colect dates after the patients fill the questionaires	Colect dates after the patients fill the questionaires	-	-	NO
4493629	26161157	Moises Cohen	7	Surgeon and text review	Surgeon and text review	Wrote the paper	Writing - Review & Editing	YES
4493629	26161157	Nelson Astur	7	Text review and methodology	Text review and methodology	Performed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5499034	28721214	Abdulwahid M. Salih	7	substantial contribution of the concept and design, acquisition of the data, final approval	substantial contribution of the concept and design, acquisition of the data, final approval	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceptualization|Investigation|Resources	YES
5499034	28721214	Aso S. Muhialdeen	7	substantial contribution of the concept and design, analysis of data, drafting the manuscript, final approval of the data	substantial contribution of the concept and design, analysis of data, drafting the manuscript, final approval of the data	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Resources|Writing - Original Draft	YES
5499034	28721214	F.M.R.	7	substantial contribution of the concept and design, acquisition of the data, final approval	substantial contribution of the concept and design, acquisition of the data, final approval	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceptualization|Investigation|Resources	YES
5499034	28721214	H. Kakamad	7	substantial contribution of the concept and design, drafting the manuscript and final approval of the manuscript. Rawezh Q.Salih, Hawbash	substantial contribution of the concept and design, drafting the manuscript and final approval of the manuscript. Rawezh Q.Salih, Hawbash	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5499034	28721214	Hiwa O. Baba	7	substantial contribution of the concept and design, drafting the manuscript and final approval of the manuscript. Rawezh Q.Salih, Hawbash	substantial contribution of the concept and design, drafting the manuscript and final approval of the manuscript. Rawezh Q.Salih, Hawbash	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5499034	28721214	Imad J. Habibullah	7	substantial contribution of the concept and design, analysis of data, drafting the manuscript, final approval of the data	substantial contribution of the concept and design, analysis of data, drafting the manuscript, final approval of the data	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Resources|Writing - Original Draft	YES
5499034	28721214	Nawshirwan H. Abdulkarim	7	substantial contribution of the concept and design, analysis of data, drafting the manuscript, final approval of the data	substantial contribution of the concept and design, analysis of data, drafting the manuscript, final approval of the data	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Resources|Writing - Original Draft	YES
5499034	28721214	Rebaz O. Nawroly	7	substantial contribution of the concept and design, analysis of data, drafting the manuscript, final approval of the data	substantial contribution of the concept and design, analysis of data, drafting the manuscript, final approval of the data	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Resources|Writing - Original Draft	YES
5499034	28721214	Shvan H. Mohammed	7	substantial contribution of the concept and design, acquisition of the data, final approval	substantial contribution of the concept and design, acquisition of the data, final approval	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceptualization|Investigation|Resources	YES
5499034	28721214	Snur Othman	7	substantial contribution of the concept and design, acquisition of the data, final approval	substantial contribution of the concept and design, acquisition of the data, final approval	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceptualization|Investigation|Resources	YES
5499034	28721214	Yadgar A. Saeed	7	substantial contribution of the concept and design, analysis of data, drafting the manuscript, final approval of the data	substantial contribution of the concept and design, analysis of data, drafting the manuscript, final approval of the data	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Resources|Writing - Original Draft	YES
5499034	28721214	Zuhair D. Hammood	7	substantial contribution of the concept and design, analysis of data, drafting the manuscript, final approval of the data	substantial contribution of the concept and design, analysis of data, drafting the manuscript, final approval of the data	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Resources|Writing - Original Draft	YES
4904089	27293220	All authors	2	contributed to the interpretation of the results and to the final version of the manuscript	contributed to the interpretation of the results and to the final version of the manuscript	Analyzed the data	Formal analysis	YES
4904089	27293220	GW	2	designed the study|performed the statistical analyses|performed the data extraction and wrote the first draft of the manuscript|had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis	designed the study	Conceived and designed the experiments	Methodology	YES
4904089	27293220	GW	2	designed the study|performed the statistical analyses|performed the data extraction and wrote the first draft of the manuscript|had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis	performed the statistical analyses	Analyzed the data	Formal analysis	YES
4904089	27293220	GW	2	designed the study|performed the statistical analyses|performed the data extraction and wrote the first draft of the manuscript|had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis	performed the data extraction and wrote the first draft of the manuscript	Analyzed the data|Wrote the paper	Data curation|Writing - Original Draft	YES
4904089	27293220	GW	2	designed the study|performed the statistical analyses|performed the data extraction and wrote the first draft of the manuscript|had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis	had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis	Analyzed the data	Data curation|Formal analysis	YES
4904089	27293220	ME	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
4904089	27293220	MZ	2	performed the statistical analyses	performed the statistical analyses	Analyzed the data	Formal analysis	YES
4904089	27293220	TC	2	designed the study|performed the data extraction and wrote the first draft of the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
4904089	27293220	TC	2	designed the study|performed the data extraction and wrote the first draft of the manuscript	performed the data extraction and wrote the first draft of the manuscript	Analyzed the data|Wrote the paper	Data curation|Writing - Original Draft	YES
4412688	25870032	Juan Tamargo	2	performed the literature search and drafted the manuscript	performed the literature search and drafted the manuscript	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4412688	25870032	Philippe Mabo	2	reviewed the manuscript for its intellectual content and interpretation of data	reviewed the manuscript for its intellectual content and interpretation of data	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4412688	25870032	Yves Le Heuzey	2	reviewed the manuscript for its intellectual content and interpretation of data	reviewed the manuscript for its intellectual content and interpretation of data	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5309989	28196471	GY	2	contributed to the study design or manuscript revision	contributed to the study design or manuscript revision	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5309989	28196471	HL	2	participated in the design of the study, carried out the bioinformatics analysis and drafted the manuscript|carried out the biological experiments	participated in the design of the study, carried out the bioinformatics analysis and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5309989	28196471	HL	2	participated in the design of the study, carried out the bioinformatics analysis and drafted the manuscript|carried out the biological experiments	carried out the biological experiments	Performed the experiments	Investigation	YES
5309989	28196471	JZ	2	carried out the biological experiments	carried out the biological experiments	Performed the experiments	Investigation	YES
5309989	28196471	MY	2	contributed to the study design or manuscript revision	contributed to the study design or manuscript revision	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5309989	28196471	XL	2	carried out the biological experiments	carried out the biological experiments	Performed the experiments	Investigation	YES
5309989	28196471	XX	2	contributed to the study design or manuscript revision	contributed to the study design or manuscript revision	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5309989	28196471	XY	2	contributed to the study design or manuscript revision	contributed to the study design or manuscript revision	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5309989	28196471	YF	2	carried out the statistical analysis	carried out the statistical analysis	Analyzed the data	Formal analysis	YES
6025562	29843402	M.B.	PLoS52	conceived and designed the study|performed the administration of the survey for the study|wrote the paper	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6025562	29843402	M.B.	PLoS52	conceived and designed the study|performed the administration of the survey for the study|wrote the paper	performed the administration of the survey for the study	Performed the experiments	Investigation|Project administration	YES
6025562	29843402	M.B.	PLoS52	conceived and designed the study|performed the administration of the survey for the study|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6025562	29843402	M.N.	PLoS52	conceived and designed the study|analyzed the data|wrote the paper	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6025562	29843402	M.N.	PLoS52	conceived and designed the study|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
6025562	29843402	M.N.	PLoS52	conceived and designed the study|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405584	25897763	BS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405584	25897763	BS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405584	25897763	BS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405584	25897763	COL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405584	25897763	COL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405584	25897763	COL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405584	25897763	COL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405584	25897763	CP	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405584	25897763	CP	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405584	25897763	HCW	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405584	25897763	HCW	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405584	25897763	HCW	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405584	25897763	JS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405584	25897763	JS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405584	25897763	KST	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405584	25897763	KST	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405584	25897763	KST	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405584	25897763	SL	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405584	25897763	SL	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405584	25897763	SL	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5508225	28725423	Li Guojian	2	substantial contributions to conception and design of the study, acquisition of data, or analysis and interpretation of data	substantial contributions to conception and design of the study, acquisition of data, or analysis and interpretation of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Methodology|Resources	YES
5508225	28725423	Ren Chongxi	2	drafting the article or making critical revisions related to important intellectual content of the manuscript	drafting the article or making critical revisions related to important intellectual content of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5508225	28725423	Wang Xia	2	drafting the article or making critical revisions related to important intellectual content of the manuscript	drafting the article or making critical revisions related to important intellectual content of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5508225	28725423	Xin Xiao	2	drafting the article or making critical revisions related to important intellectual content of the manuscript	drafting the article or making critical revisions related to important intellectual content of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5550725	28848565	CZ	2	carried out the data collection experiments	carried out the data collection experiments	Performed the experiments	Investigation	YES
5550725	28848565	HB	2	analyzed the modeling strategy experiment results|wrote the manuscript	analyzed the modeling strategy experiment results	Performed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5550725	28848565	HB	2	analyzed the modeling strategy experiment results|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5550725	28848565	JY	2	discussed the data and revised the article	discussed the data and revised the article	Wrote the paper	Writing - Review & Editing	YES
5550725	28848565	KS	2	designed the data collection experiments|wrote the manuscript	designed the data collection experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5550725	28848565	KS	2	designed the data collection experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5550725	28848565	QQ	2	designed the modeling strategy|developed the modeling strategy experiment codes|analyzed the modeling strategy experiment results|wrote the manuscript	designed the modeling strategy	Conceived and designed the experiments|Performed the experiments	Methodology	YES
5550725	28848565	QQ	2	designed the modeling strategy|developed the modeling strategy experiment codes|analyzed the modeling strategy experiment results|wrote the manuscript	developed the modeling strategy experiment codes	Performed the experiments	Methodology|Software	YES
5550725	28848565	QQ	2	designed the modeling strategy|developed the modeling strategy experiment codes|analyzed the modeling strategy experiment results|wrote the manuscript	analyzed the modeling strategy experiment results	Performed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5550725	28848565	QQ	2	designed the modeling strategy|developed the modeling strategy experiment codes|analyzed the modeling strategy experiment results|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5550725	28848565	WW	2	carried out the data collection experiments	carried out the data collection experiments	Performed the experiments	Investigation	YES
5550725	28848565	XQ	2	developed the modeling strategy experiment codes	developed the modeling strategy experiment codes	Performed the experiments	Methodology|Software	YES
5508488	28736612	Perrotta E. Rosario	2	study design	study design	Conceived and designed the experiments	Methodology	YES
5508488	28736612	Raposio Edoardo	2	study design	study design	Conceived and designed the experiments	Methodology	YES
5309995	28196481	KR	2	conceived the study, coordinated the research and wrote the manuscript	conceived the study, coordinated the research and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Project administration|Writing - Original Draft	YES
5309995	28196481	VBT	2	developed the software and performed data analysis|conceived the study, coordinated the research and wrote the manuscript	developed the software and performed data analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Software	YES
5309995	28196481	VBT	2	developed the software and performed data analysis|conceived the study, coordinated the research and wrote the manuscript	conceived the study, coordinated the research and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Project administration|Writing - Original Draft	YES
5309995	28196481	YV	2	developed the software and performed data analysis|conceived the study, coordinated the research and wrote the manuscript	developed the software and performed data analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Software	YES
5309995	28196481	YV	2	developed the software and performed data analysis|conceived the study, coordinated the research and wrote the manuscript	conceived the study, coordinated the research and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Project administration|Writing - Original Draft	YES
6025602	29857579	K.B.	PLoS52	conceived and designed the intervention|taught the graduate classes and implemented the protocol|wrote the paper	conceived and designed the intervention	Conceived and designed the experiments	Conceptualization	YES
6025602	29857579	K.B.	PLoS52	conceived and designed the intervention|taught the graduate classes and implemented the protocol|wrote the paper	taught the graduate classes and implemented the protocol	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6025602	29857579	K.B.	PLoS52	conceived and designed the intervention|taught the graduate classes and implemented the protocol|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6025602	29857579	Y.B.	PLoS52	conceived and designed the intervention|analyzed the data|wrote the paper	conceived and designed the intervention	Conceived and designed the experiments	Conceptualization	YES
6025602	29857579	Y.B.	PLoS52	conceived and designed the intervention|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
6025602	29857579	Y.B.	PLoS52	conceived and designed the intervention|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3276072	22332016	Both authors	2	equally contributed to the diagnosis of the patient and the preparation of the manuscript for publication	equally contributed to the diagnosis of the patient and the preparation of the manuscript for publication	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3276072	22332016	Sahar Talaat	2	critically reviewed the manuscript	critically reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
3276072	22332016	Samia Gabal	2	wrote the manuscript and did the pathological analysis and discussion	wrote the manuscript and did the pathological analysis and discussion	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4405585	25898138	CDD	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405585	25898138	CDD	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405585	25898138	IS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405585	25898138	IS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405585	25898138	IS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405585	25898138	IS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405585	25898138	IS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405585	25898138	JT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405585	25898138	JT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405585	25898138	JT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405585	25898138	JT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405585	25898138	KA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405585	25898138	KA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405585	25898138	KA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405585	25898138	KA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405585	25898138	LATN	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405585	25898138	LATN	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405585	25898138	LATN	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405585	25898138	LATN	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405585	25898138	LMY	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405585	25898138	LMY	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405585	25898138	LMY	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405585	25898138	LMY	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405585	25898138	NT	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405585	25898138	NT	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405585	25898138	QPL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405585	25898138	QPL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405585	25898138	QPL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405585	25898138	QPL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405585	25898138	SO	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405585	25898138	SO	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405585	25898138	SO	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405585	25898138	SO	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405585	25898138	TQN	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405585	25898138	TQN	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405585	25898138	TS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405585	25898138	TS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405585	25898138	TS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405585	25898138	TTD	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405585	25898138	TTD	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405585	25898138	TTTP	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405585	25898138	TTTP	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405585	25898138	TVTV	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405585	25898138	TVTV	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4911420	27312984	AA	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4911420	27312984	AYB	2	contributed to the design of the study	contributed to the design of the study	Conceived and designed the experiments	Methodology	YES
4911420	27312984	EAB	2	contributed to the design of the study|interpreted the data|wrote the manuscript	contributed to the design of the study	Conceived and designed the experiments	Methodology	YES
4911420	27312984	EAB	2	contributed to the design of the study|interpreted the data|wrote the manuscript	interpreted the data	Analyzed the data	Formal analysis	YES
4911420	27312984	EAB	2	contributed to the design of the study|interpreted the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4911420	27312984	HZ	2	led the implementation of the study|interpreted the data|wrote the manuscript	led the implementation of the study	Performed the experiments	Investigation	YES
4911420	27312984	HZ	2	led the implementation of the study|interpreted the data|wrote the manuscript	interpreted the data	Analyzed the data	Formal analysis	YES
4911420	27312984	HZ	2	led the implementation of the study|interpreted the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4911420	27312984	KMM	2	interpreted the data|wrote the manuscript	interpreted the data	Analyzed the data	Formal analysis	YES
4911420	27312984	KMM	2	interpreted the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4911420	27312984	LK	2	contributed to the design of the study|contributed to the conduct|interpreted the data|wrote the manuscript	contributed to the design of the study	Conceived and designed the experiments	Methodology	YES
4911420	27312984	LK	2	contributed to the design of the study|contributed to the conduct|interpreted the data|wrote the manuscript	contributed to the conduct	Performed the experiments	Investigation	YES
4911420	27312984	LK	2	contributed to the design of the study|contributed to the conduct|interpreted the data|wrote the manuscript	interpreted the data	Analyzed the data	Formal analysis	YES
4911420	27312984	LK	2	contributed to the design of the study|contributed to the conduct|interpreted the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4911420	27312984	MP	2	contributed to the design of the study|contributed to the conduct|wrote the manuscript	contributed to the design of the study	Conceived and designed the experiments	Methodology	YES
4911420	27312984	MP	2	contributed to the design of the study|contributed to the conduct|wrote the manuscript	contributed to the conduct	Performed the experiments	Investigation	YES
4911420	27312984	MP	2	contributed to the design of the study|contributed to the conduct|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4911420	27312984	NB	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4911420	27312984	TT	2	interpreted the data|wrote the manuscript	interpreted the data	Analyzed the data	Formal analysis	YES
4911420	27312984	TT	2	interpreted the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5550759	28848575	All authors	PLoS52	read and approved the manuscript	read and approved the manuscript	-	-	NO
5550759	28848575	GQ	PLoS52	analyzed the data and wrote the paper	analyzed the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5550759	28848575	HL	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5550759	28848575	HY	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5550759	28848575	KS	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5550759	28848575	ML	PLoS52	analyzed the data and wrote the paper	analyzed the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5550759	28848575	RZ	PLoS52	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5550759	28848575	YY	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
6163164	30142920	C.E.O.	CRediT	Conceptualization|Methodology|Validation|Investigation|Resources|Data curation|Writing-review & editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6163164	30142920	C.E.O.	CRediT	Conceptualization|Methodology|Validation|Investigation|Resources|Data curation|Writing-review & editing	Methodology	Performed the experiments	Methodology	YES
6163164	30142920	C.E.O.	CRediT	Conceptualization|Methodology|Validation|Investigation|Resources|Data curation|Writing-review & editing	Validation	Performed the experiments	Validation	YES
6163164	30142920	C.E.O.	CRediT	Conceptualization|Methodology|Validation|Investigation|Resources|Data curation|Writing-review & editing	Investigation	Performed the experiments	Investigation	YES
6163164	30142920	C.E.O.	CRediT	Conceptualization|Methodology|Validation|Investigation|Resources|Data curation|Writing-review & editing	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6163164	30142920	C.E.O.	CRediT	Conceptualization|Methodology|Validation|Investigation|Resources|Data curation|Writing-review & editing	Data curation	Analyzed the data	Data curation	YES
6163164	30142920	C.E.O.	CRediT	Conceptualization|Methodology|Validation|Investigation|Resources|Data curation|Writing-review & editing	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6163164	30142920	D.I.P.	CRediT	Conceptualization|Methodology|Validation|Investigation|Resources|Data curation|Writing-review & editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6163164	30142920	D.I.P.	CRediT	Conceptualization|Methodology|Validation|Investigation|Resources|Data curation|Writing-review & editing	Methodology	Performed the experiments	Methodology	YES
6163164	30142920	D.I.P.	CRediT	Conceptualization|Methodology|Validation|Investigation|Resources|Data curation|Writing-review & editing	Validation	Performed the experiments	Validation	YES
6163164	30142920	D.I.P.	CRediT	Conceptualization|Methodology|Validation|Investigation|Resources|Data curation|Writing-review & editing	Investigation	Performed the experiments	Investigation	YES
6163164	30142920	D.I.P.	CRediT	Conceptualization|Methodology|Validation|Investigation|Resources|Data curation|Writing-review & editing	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6163164	30142920	D.I.P.	CRediT	Conceptualization|Methodology|Validation|Investigation|Resources|Data curation|Writing-review & editing	Data curation	Analyzed the data	Data curation	YES
6163164	30142920	D.I.P.	CRediT	Conceptualization|Methodology|Validation|Investigation|Resources|Data curation|Writing-review & editing	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6163164	30142920	J.M.L.	CRediT	Conceptualization|Methodology|Software|Validation|Formal analysis|Investigation|Resources|Data curation|Writing-original draft preparation|Writing-review & editing|Visualization|Supervision|Project administration	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6163164	30142920	J.M.L.	CRediT	Conceptualization|Methodology|Software|Validation|Formal analysis|Investigation|Resources|Data curation|Writing-original draft preparation|Writing-review & editing|Visualization|Supervision|Project administration	Methodology	Performed the experiments	Methodology	YES
6163164	30142920	J.M.L.	CRediT	Conceptualization|Methodology|Software|Validation|Formal analysis|Investigation|Resources|Data curation|Writing-original draft preparation|Writing-review & editing|Visualization|Supervision|Project administration	Software	Contributed reagents/materials/analysis tools	Software	YES
6163164	30142920	J.M.L.	CRediT	Conceptualization|Methodology|Software|Validation|Formal analysis|Investigation|Resources|Data curation|Writing-original draft preparation|Writing-review & editing|Visualization|Supervision|Project administration	Validation	Performed the experiments	Validation	YES
6163164	30142920	J.M.L.	CRediT	Conceptualization|Methodology|Software|Validation|Formal analysis|Investigation|Resources|Data curation|Writing-original draft preparation|Writing-review & editing|Visualization|Supervision|Project administration	Formal analysis	Analyzed the data	Formal analysis	YES
6163164	30142920	J.M.L.	CRediT	Conceptualization|Methodology|Software|Validation|Formal analysis|Investigation|Resources|Data curation|Writing-original draft preparation|Writing-review & editing|Visualization|Supervision|Project administration	Investigation	Performed the experiments	Investigation	YES
6163164	30142920	J.M.L.	CRediT	Conceptualization|Methodology|Software|Validation|Formal analysis|Investigation|Resources|Data curation|Writing-original draft preparation|Writing-review & editing|Visualization|Supervision|Project administration	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6163164	30142920	J.M.L.	CRediT	Conceptualization|Methodology|Software|Validation|Formal analysis|Investigation|Resources|Data curation|Writing-original draft preparation|Writing-review & editing|Visualization|Supervision|Project administration	Data curation	Analyzed the data	Data curation	YES
6163164	30142920	J.M.L.	CRediT	Conceptualization|Methodology|Software|Validation|Formal analysis|Investigation|Resources|Data curation|Writing-original draft preparation|Writing-review & editing|Visualization|Supervision|Project administration	Writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
6163164	30142920	J.M.L.	CRediT	Conceptualization|Methodology|Software|Validation|Formal analysis|Investigation|Resources|Data curation|Writing-original draft preparation|Writing-review & editing|Visualization|Supervision|Project administration	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6163164	30142920	J.M.L.	CRediT	Conceptualization|Methodology|Software|Validation|Formal analysis|Investigation|Resources|Data curation|Writing-original draft preparation|Writing-review & editing|Visualization|Supervision|Project administration	Visualization	Analyzed the data	Visualization	YES
6163164	30142920	J.M.L.	CRediT	Conceptualization|Methodology|Software|Validation|Formal analysis|Investigation|Resources|Data curation|Writing-original draft preparation|Writing-review & editing|Visualization|Supervision|Project administration	Supervision	-	Supervision	YES
6163164	30142920	J.M.L.	CRediT	Conceptualization|Methodology|Software|Validation|Formal analysis|Investigation|Resources|Data curation|Writing-original draft preparation|Writing-review & editing|Visualization|Supervision|Project administration	Project administration	-	Project administration	YES
6163164	30142920	L.R.G.	CRediT	Conceptualization|Methodology|Validation|Investigation|Resources|Data curation|Writing-review & editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6163164	30142920	L.R.G.	CRediT	Conceptualization|Methodology|Validation|Investigation|Resources|Data curation|Writing-review & editing	Methodology	Performed the experiments	Methodology	YES
6163164	30142920	L.R.G.	CRediT	Conceptualization|Methodology|Validation|Investigation|Resources|Data curation|Writing-review & editing	Validation	Performed the experiments	Validation	YES
6163164	30142920	L.R.G.	CRediT	Conceptualization|Methodology|Validation|Investigation|Resources|Data curation|Writing-review & editing	Investigation	Performed the experiments	Investigation	YES
6163164	30142920	L.R.G.	CRediT	Conceptualization|Methodology|Validation|Investigation|Resources|Data curation|Writing-review & editing	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6163164	30142920	L.R.G.	CRediT	Conceptualization|Methodology|Validation|Investigation|Resources|Data curation|Writing-review & editing	Data curation	Analyzed the data	Data curation	YES
6163164	30142920	L.R.G.	CRediT	Conceptualization|Methodology|Validation|Investigation|Resources|Data curation|Writing-review & editing	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6163164	30142920	L.T.H.	CRediT	Conceptualization|Methodology|Software|Validation|Formal analysis|Investigation|Resources|Data curation|Writing-original draft preparation|Writing-review & editing|Visualization|Supervision|Project administration	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6163164	30142920	L.T.H.	CRediT	Conceptualization|Methodology|Software|Validation|Formal analysis|Investigation|Resources|Data curation|Writing-original draft preparation|Writing-review & editing|Visualization|Supervision|Project administration	Methodology	Performed the experiments	Methodology	YES
6163164	30142920	L.T.H.	CRediT	Conceptualization|Methodology|Software|Validation|Formal analysis|Investigation|Resources|Data curation|Writing-original draft preparation|Writing-review & editing|Visualization|Supervision|Project administration	Software	Contributed reagents/materials/analysis tools	Software	YES
6163164	30142920	L.T.H.	CRediT	Conceptualization|Methodology|Software|Validation|Formal analysis|Investigation|Resources|Data curation|Writing-original draft preparation|Writing-review & editing|Visualization|Supervision|Project administration	Validation	Performed the experiments	Validation	YES
6163164	30142920	L.T.H.	CRediT	Conceptualization|Methodology|Software|Validation|Formal analysis|Investigation|Resources|Data curation|Writing-original draft preparation|Writing-review & editing|Visualization|Supervision|Project administration	Formal analysis	Analyzed the data	Formal analysis	YES
6163164	30142920	L.T.H.	CRediT	Conceptualization|Methodology|Software|Validation|Formal analysis|Investigation|Resources|Data curation|Writing-original draft preparation|Writing-review & editing|Visualization|Supervision|Project administration	Investigation	Performed the experiments	Investigation	YES
6163164	30142920	L.T.H.	CRediT	Conceptualization|Methodology|Software|Validation|Formal analysis|Investigation|Resources|Data curation|Writing-original draft preparation|Writing-review & editing|Visualization|Supervision|Project administration	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6163164	30142920	L.T.H.	CRediT	Conceptualization|Methodology|Software|Validation|Formal analysis|Investigation|Resources|Data curation|Writing-original draft preparation|Writing-review & editing|Visualization|Supervision|Project administration	Data curation	Analyzed the data	Data curation	YES
6163164	30142920	L.T.H.	CRediT	Conceptualization|Methodology|Software|Validation|Formal analysis|Investigation|Resources|Data curation|Writing-original draft preparation|Writing-review & editing|Visualization|Supervision|Project administration	Writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
6163164	30142920	L.T.H.	CRediT	Conceptualization|Methodology|Software|Validation|Formal analysis|Investigation|Resources|Data curation|Writing-original draft preparation|Writing-review & editing|Visualization|Supervision|Project administration	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6163164	30142920	L.T.H.	CRediT	Conceptualization|Methodology|Software|Validation|Formal analysis|Investigation|Resources|Data curation|Writing-original draft preparation|Writing-review & editing|Visualization|Supervision|Project administration	Visualization	Analyzed the data	Visualization	YES
6163164	30142920	L.T.H.	CRediT	Conceptualization|Methodology|Software|Validation|Formal analysis|Investigation|Resources|Data curation|Writing-original draft preparation|Writing-review & editing|Visualization|Supervision|Project administration	Supervision	-	Supervision	YES
6163164	30142920	L.T.H.	CRediT	Conceptualization|Methodology|Software|Validation|Formal analysis|Investigation|Resources|Data curation|Writing-original draft preparation|Writing-review & editing|Visualization|Supervision|Project administration	Project administration	-	Project administration	YES
5310006	28201992	HZ	2	conceived the study and revised the manuscript	conceived the study and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5310006	28201992	MJH	2	carried out the biochemical assays and hplc experiment, drafted and revised the manuscript	carried out the biochemical assays and hplc experiment, drafted and revised the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5310006	28201992	XRM	2	conceived the study and revised the manuscript	conceived the study and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5310006	28201992	XT	2	conceived the study, carried out the data analysis, drafted and revised the manuscript	conceived the study, carried out the data analysis, drafted and revised the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5310006	28201992	YF	2	drafted and revised the manuscript	drafted and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5310006	28201992	YL	2	carried out the biochemical assays and revised the manuscript	carried out the biochemical assays and revised the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5310006	28201992	YX	2	carried out the data analysis and revised the manuscript	carried out the data analysis and revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4405586	25898213	FW	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405586	25898213	FW	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405586	25898213	LZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405586	25898213	YLZ	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4405586	25898213	ZQ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4911732	27265490	DHST	2	conceived the study idea and supervised all aspects of its execution|planned and performed the statistical analysis|wrote the original draft of the manuscript	conceived the study idea and supervised all aspects of its execution	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Supervision	YES
4911732	27265490	DHST	2	conceived the study idea and supervised all aspects of its execution|planned and performed the statistical analysis|wrote the original draft of the manuscript	planned and performed the statistical analysis	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
4911732	27265490	DHST	2	conceived the study idea and supervised all aspects of its execution|planned and performed the statistical analysis|wrote the original draft of the manuscript	wrote the original draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
4911732	27265490	JW	2	planned and performed the statistical analysis|wrote the original draft of the manuscript	planned and performed the statistical analysis	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
4911732	27265490	JW	2	planned and performed the statistical analysis|wrote the original draft of the manuscript	wrote the original draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
4911732	27265490	SF	2	oversaw enrolment of participants into the study	oversaw enrolment of participants into the study	-	Supervision	YES
4911732	27265490	all authors	2	designed the study|provided input into and approved the final version of the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
4911732	27265490	all authors	2	designed the study|provided input into and approved the final version of the manuscript	provided input into and approved the final version of the manuscript	-	-	NO
4488517	26167508	Cuilan Zhou	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
4488517	26167508	Huifen Xu	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
5550771	28848581	All authors	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5550771	28848581	CK	PLoS52	conceived the project|edited the manuscript	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5550771	28848581	CK	PLoS52	conceived the project|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5550771	28848581	LV	PLoS52	conceived the project|wrote the manuscript	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5550771	28848581	LV	PLoS52	conceived the project|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5550771	28848581	MK	PLoS52	performed the described experiments	performed the described experiments	Performed the experiments	Investigation	YES
5550771	28848581	PG	PLoS52	performed the described experiments|wrote the manuscript	performed the described experiments	Performed the experiments	Investigation	YES
5550771	28848581	PG	PLoS52	performed the described experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5550771	28848581	TE	PLoS52	performed the described experiments	performed the described experiments	Performed the experiments	Investigation	YES
5550771	28848581	US	PLoS52	conceived the project|edited the manuscript	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5550771	28848581	US	PLoS52	conceived the project|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5522913	28761637	Data Analysis	1	Mirzaee	Mirzaee	-	-	NO
5522913	28761637	Data Collection	1	Mirzaee	Mirzaee	-	-	NO
5522913	28761637	Study Design	1	Mirzaee	Mirzaee	-	-	NO
5310007	28196477	CHG	2	carried out the analysis of data, animal experiments, and surgical processes	carried out the analysis of data, animal experiments, and surgical processes	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5310007	28196477	DJP	2	performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
5310007	28196477	FFG	2	participated in the design and coordination and helped to draft the manuscript	participated in the design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Project administration|Writing - Original Draft	YES
5310007	28196477	GXX	2	conceived of the study, participated in its design and coordination and drafted the manuscript	conceived of the study, participated in its design and coordination and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
5310007	28196477	LL	2	conducted qrt pcr validation and statistical analysis	conducted qrt pcr validation and statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Validation	YES
5310007	28196477	LXM	2	conducted qrt pcr validation and statistical analysis	conducted qrt pcr validation and statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Validation	YES
5310007	28196477	LY	2	carried out the analysis of data, animal experiments, and surgical processes	carried out the analysis of data, animal experiments, and surgical processes	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5310007	28196477	LYH	2	carried out the analysis of data, animal experiments, and surgical processes	carried out the analysis of data, animal experiments, and surgical processes	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5310007	28196477	LYS	2	performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
5310007	28196477	YC	2	conducted qrt pcr validation and statistical analysis	conducted qrt pcr validation and statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Validation	YES
5310007	28196477	YJ	2	conceived of the study, participated in its design and coordination and drafted the manuscript	conceived of the study, participated in its design and coordination and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
5310007	28196477	ZKF	2	conducted qrt pcr validation and statistical analysis	conducted qrt pcr validation and statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Validation	YES
5310007	28196477	ZXR	2	carried out the analysis of data, animal experiments, and surgical processes	carried out the analysis of data, animal experiments, and surgical processes	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5310007	28196477	ZYH	2	participated in the design and coordination and helped to draft the manuscript	participated in the design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Project administration|Writing - Original Draft	YES
6163181	29997322	All Authors	CRediT	Writing-review & editing	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6163181	29997322	D.V.	CRediT	Conceptualization|Methodology|Investigation|Writing-original draft preparation	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6163181	29997322	D.V.	CRediT	Conceptualization|Methodology|Investigation|Writing-original draft preparation	Methodology	Performed the experiments	Methodology	YES
6163181	29997322	D.V.	CRediT	Conceptualization|Methodology|Investigation|Writing-original draft preparation	Investigation	Performed the experiments	Investigation	YES
6163181	29997322	D.V.	CRediT	Conceptualization|Methodology|Investigation|Writing-original draft preparation	Writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
6163181	29997322	E.R.	CRediT	Conceptualization|Methodology|Investigation	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6163181	29997322	E.R.	CRediT	Conceptualization|Methodology|Investigation	Methodology	Performed the experiments	Methodology	YES
6163181	29997322	E.R.	CRediT	Conceptualization|Methodology|Investigation	Investigation	Performed the experiments	Investigation	YES
6163181	29997322	J.M.	CRediT	Formal analysis|Writing-original draft preparation	Formal analysis	Analyzed the data	Formal analysis	YES
6163181	29997322	J.M.	CRediT	Formal analysis|Writing-original draft preparation	Writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
6163181	29997322	S.G.	CRediT	Conceptualization|Methodology|Investigation|Data curation|Writing-original draft preparation	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6163181	29997322	S.G.	CRediT	Conceptualization|Methodology|Investigation|Data curation|Writing-original draft preparation	Methodology	Performed the experiments	Methodology	YES
6163181	29997322	S.G.	CRediT	Conceptualization|Methodology|Investigation|Data curation|Writing-original draft preparation	Investigation	Performed the experiments	Investigation	YES
6163181	29997322	S.G.	CRediT	Conceptualization|Methodology|Investigation|Data curation|Writing-original draft preparation	Data curation	Analyzed the data	Data curation	YES
6163181	29997322	S.G.	CRediT	Conceptualization|Methodology|Investigation|Data curation|Writing-original draft preparation	Writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
6163181	29997322	S.P.	CRediT	Investigation|Data curation|Writing-original draft preparation	Investigation	Performed the experiments	Investigation	YES
6163181	29997322	S.P.	CRediT	Investigation|Data curation|Writing-original draft preparation	Data curation	Analyzed the data	Data curation	YES
6163181	29997322	S.P.	CRediT	Investigation|Data curation|Writing-original draft preparation	Writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
6163181	29997322	S.R.	CRediT	Investigation|Data curation|Writing-original draft preparation	Investigation	Performed the experiments	Investigation	YES
6163181	29997322	S.R.	CRediT	Investigation|Data curation|Writing-original draft preparation	Data curation	Analyzed the data	Data curation	YES
6163181	29997322	S.R.	CRediT	Investigation|Data curation|Writing-original draft preparation	Writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
4405587	25897667	BB	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405587	25897667	BB	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405587	25897667	BTM	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405587	25897667	BTM	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405587	25897667	DG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405587	25897667	DG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405587	25897667	DG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405587	25897667	DG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405587	25897667	DG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405587	25897667	YT	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405587	25897667	YT	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3137978	21776380	C. A. Wanke	2	provided critical and substantive reviews of the final manuscript	provided critical and substantive reviews of the final manuscript	Wrote the paper	Writing - Review & Editing	YES
3137978	21776380	D. V. Duong	2	were involved in the conception, design, and implementation of the study	were involved in the conception, design, and implementation of the study	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
3137978	21776380	H. B. Sheehan	2	conducted statistical analysis and assisted in the manuscript preparation	conducted statistical analysis and assisted in the manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3137978	21776380	K. Dong	2	trained the study staff, were involved in data management, and assisted in paper preparation	trained the study staff, were involved in data management, and assisted in paper preparation	Analyzed the data	Data curation	YES
3137978	21776380	M. R. Jordan	2	provided critical and substantive reviews of the final manuscript	provided critical and substantive reviews of the final manuscript	Wrote the paper	Writing - Review & Editing	YES
3137978	21776380	M. Tang	2	drafted the paper and was involved in all aspects of the study	drafted the paper and was involved in all aspects of the study	Wrote the paper	Writing - Original Draft	YES
3137978	21776380	N. D. Hien	2	were involved in the conception, design, and implementation of the study	were involved in the conception, design, and implementation of the study	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
3137978	21776380	N. Terrin	2	conducted statistical analysis and assisted in the manuscript preparation	conducted statistical analysis and assisted in the manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3137978	21776380	N. V. Trung	2	were involved in the conception, design, and implementation of the study	were involved in the conception, design, and implementation of the study	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
3137978	21776380	T. T. M. Lien	2	trained the study staff, were involved in data management, and assisted in paper preparation	trained the study staff, were involved in data management, and assisted in paper preparation	Analyzed the data	Data curation	YES
4913145	27319742	AKa	PLoS52	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4913145	27319742	AKi	PLoS52	supervised the data analysis	supervised the data analysis	Analyzed the data	Formal analysis|Supervision	YES
4913145	27319742	BC	PLoS52	wrote the first draft of the manuscript and planned the data analysis	wrote the first draft of the manuscript and planned the data analysis	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
4913145	27319742	FM	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
4913145	27319742	MK	PLoS52	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4913145	27319742	SJR	PLoS52	provided overall supervision of the manuscript writing	provided overall supervision of the manuscript writing	Wrote the paper	Supervision|Writing - Original Draft	YES
4405588	25898360	BSS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405588	25898360	CSK	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4405588	25898360	D-KK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405588	25898360	H-JK	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405588	25898360	H-JK	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405588	25898360	H-JK	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405588	25898360	H-JK	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405588	25898360	HWL	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405588	25898360	HWL	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405588	25898360	JAK	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405588	25898360	JAK	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405588	25898360	SML	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405588	25898360	SML	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405588	25898360	SML	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405588	25898360	TSH	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4405588	25898360	TSH	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405588	25898360	WHK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405588	25898360	WHK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405588	25898360	WHK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405588	25898360	WHK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405588	25898360	WHK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405588	25898360	WSS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5522914	28761638	Abd El-Aziz	7	data collections, data analysis, writing	data collections, data analysis, writing	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation	YES
5522914	28761638	Ahmad A. Sobeih	7	study design, data collections	study design, data collections	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5522914	28761638	Eman G. Behiry	7	data collections, data analysis, writing. Mahmoud A	data collections, data analysis, writing. Mahmoud A	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation	YES
5522914	28761638	Mohsen M. Shalaby	7	study design, data collections	study design, data collections	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5522914	28761638	Waleed E. Abdulghany	7	study design, data collections	study design, data collections	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5522914	28761638	Yasser M. Ismail	7	data collections, data analysis, writing	data collections, data analysis, writing	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation	YES
5550799	28848583	BI	7	Performed the experiments, done bioinformatics and statistics and wrote the paper	Performed the experiments, done bioinformatics and statistics and wrote the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5550799	28848583	MH	7	Supervised, conceived, designed the experiments and wrote the paper	Supervised, conceived, designed the experiments and wrote the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Supervision|Writing - Original Draft	YES
5550799	28848583	MS-A	7	Helped to design the experiments and wrote the paper	Helped to design the experiments and wrote the paper	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5310021	28201991	BJL	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5310021	28201991	CMF	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5310021	28201991	EBG	PLoS5	Performed the study and analyzed the data	Performed the study and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5310021	28201991	EFM	PLoS5	Conceived and designed the experiments|Performed the study and analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5310021	28201991	EFM	PLoS5	Conceived and designed the experiments|Performed the study and analyzed the data	Performed the study and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5310021	28201991	JJD	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5310021	28201991	MV	PLoS5	Performed the study and analyzed the data	Performed the study and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5310021	28201991	SES	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5310021	28201991	SRC	PLoS5	Conceived and designed the experiments|Performed the study and analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5310021	28201991	SRC	PLoS5	Conceived and designed the experiments|Performed the study and analyzed the data|Wrote the paper	Performed the study and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5310021	28201991	SRC	PLoS5	Conceived and designed the experiments|Performed the study and analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5310021	28201991	WGQ	PLoS5	Conceived and designed the experiments|Performed the study and analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5310021	28201991	WGQ	PLoS5	Conceived and designed the experiments|Performed the study and analyzed the data|Wrote the paper	Performed the study and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5310021	28201991	WGQ	PLoS5	Conceived and designed the experiments|Performed the study and analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6163185	30134545	J.A.	2	wrote the manuscript and coordinated the revisions	wrote the manuscript and coordinated the revisions	Wrote the paper	Project administration|Writing - Original Draft|Writing - Review & Editing	YES
6163185	30134545	M.Z.C.	2	provided data and information, and helped with the revisions of the manuscript	provided data and information, and helped with the revisions of the manuscript	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Review & Editing	YES
4920943	27341885	AEE	2	designed the study, contributed to data collection, led data analysis, interpretation, manuscript development and refinement|conceived of study question and designed the study, contributed to data collection, led data analysis, interpretation, manuscript development and refinement	designed the study, contributed to data collection, led data analysis, interpretation, manuscript development and refinement	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
4920943	27341885	AEE	2	designed the study, contributed to data collection, led data analysis, interpretation, manuscript development and refinement|conceived of study question and designed the study, contributed to data collection, led data analysis, interpretation, manuscript development and refinement	conceived of study question and designed the study, contributed to data collection, led data analysis, interpretation, manuscript development and refinement	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation|Methodology	YES
4920943	27341885	AKN	2	contributed to data collection, data interpretation and manuscript critique and revision for intellectually important content	contributed to data collection, data interpretation and manuscript critique and revision for intellectually important content	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
4920943	27341885	All authors	2	reviewed drafts of the manuscript, provided suggestions for refinement and were involved in the final approval of the version for peer-review	reviewed drafts of the manuscript, provided suggestions for refinement and were involved in the final approval of the version for peer-review	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4920943	27341885	CCW	2	contributed to data interpretation, critique and revision of the manuscript for important intellectual content	contributed to data interpretation, critique and revision of the manuscript for important intellectual content	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4920943	27341885	FNK	2	contributed to data analysis, data interpretation and manuscript development, and the critique and revision of important intellectual content|contributed to data analysis, data interpretation and manuscript development, critique and revision for important intellectual content	contributed to data analysis, data interpretation and manuscript development, and the critique and revision of important intellectual content	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4920943	27341885	FNK	2	contributed to data analysis, data interpretation and manuscript development, and the critique and revision of important intellectual content|contributed to data analysis, data interpretation and manuscript development, critique and revision for important intellectual content	contributed to data analysis, data interpretation and manuscript development, critique and revision for important intellectual content	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4920943	27341885	JNS	2	contributed to data collection, data interpretation and manuscript critique and revision for intellectually important content	contributed to data collection, data interpretation and manuscript critique and revision for intellectually important content	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
4920943	27341885	NK	2	contributed to data interpretation, critique and revision of the manuscript for important intellectual content	contributed to data interpretation, critique and revision of the manuscript for important intellectual content	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4920943	27341885	RK	2	contributed to data collection	contributed to data collection	Performed the experiments	Investigation	YES
4920943	27341885	SKZ	2	contributed to study design, led data collection and contributed to manuscript development and refinement	contributed to study design, led data collection and contributed to manuscript development and refinement	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources	YES
4488523	26167506	Fausto Salaffi	2	participated in the design of the study and the acquisition and interpretation of data, performed the statistical analysis and the drafting of the paper, and gave final approval of the version of the paper to be published	participated in the design of the study and the acquisition and interpretation of data, performed the statistical analysis and the drafting of the paper, and gave final approval of the version of the paper to be published	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4488523	26167506	Marco Di Carlo	2	made substantial contributions to the conception and design of the study, participated in the acquisition of data, and was involved in revising the paper for important intellectual content	made substantial contributions to the conception and design of the study, participated in the acquisition of data, and was involved in revising the paper for important intellectual content	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Investigation|Methodology|Resources|Writing - Review & Editing	YES
4488523	26167506	Marina Carotti	2	made substantial contributions to the conception and design of the study, participated in the acquisition of data, and was involved in revising the paper for important intellectual content	made substantial contributions to the conception and design of the study, participated in the acquisition of data, and was involved in revising the paper for important intellectual content	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Investigation|Methodology|Resources|Writing - Review & Editing	YES
4488523	26167506	Marwin Gutierrez	2	participated in the conception of the study and data interpretation and was involved in drafting the paper	participated in the conception of the study and data interpretation and was involved in drafting the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
4488523	26167506	Rossella De Angelis	2	made substantial contributions to the conception and design of the study, participated in the acquisition of data, and was involved in revising the paper for important intellectual content	made substantial contributions to the conception and design of the study, participated in the acquisition of data, and was involved in revising the paper for important intellectual content	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Investigation|Methodology|Resources|Writing - Review & Editing	YES
5522917	28761639	Francesco Speziale	1	Design and paper writing	Design and paper writing	Conceived and designed the experiments|Wrote the paper	-	YES
5522917	28761639	Laura Capoccia	1	Design and paper writing	Design and paper writing	Conceived and designed the experiments|Wrote the paper	-	YES
5522917	28761639	Pasqualino Sirignano	1	Design and paper writing	Design and paper writing	Conceived and designed the experiments|Wrote the paper	-	YES
5522917	28761639	Wassim Mansour	1	Design and paper writing	Design and paper writing	Conceived and designed the experiments|Wrote the paper	-	YES
6163332	30227594	D.C.	CRediT	Study concept and design|Data curation|Statistical analysis and interpretation of data|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content	Study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6163332	30227594	D.C.	CRediT	Study concept and design|Data curation|Statistical analysis and interpretation of data|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content	Data curation	Analyzed the data	Data curation	YES
6163332	30227594	D.C.	CRediT	Study concept and design|Data curation|Statistical analysis and interpretation of data|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content	Statistical analysis and interpretation of data	Analyzed the data	Formal analysis	YES
6163332	30227594	D.C.	CRediT	Study concept and design|Data curation|Statistical analysis and interpretation of data|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content	Drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
6163332	30227594	D.C.	CRediT	Study concept and design|Data curation|Statistical analysis and interpretation of data|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content	Critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
6163332	30227594	S.C.	CRediT	Study concept and design|Statistical analysis and interpretation of data|Critical revision of the manuscript for important intellectual content|Funding acquisition	Study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6163332	30227594	S.C.	CRediT	Study concept and design|Statistical analysis and interpretation of data|Critical revision of the manuscript for important intellectual content|Funding acquisition	Statistical analysis and interpretation of data	Analyzed the data	Formal analysis	YES
6163332	30227594	S.C.	CRediT	Study concept and design|Statistical analysis and interpretation of data|Critical revision of the manuscript for important intellectual content|Funding acquisition	Critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
6163332	30227594	S.C.	CRediT	Study concept and design|Statistical analysis and interpretation of data|Critical revision of the manuscript for important intellectual content|Funding acquisition	Funding acquisition	-	Funding acquisition	YES
4923264	27349912	AK	2	critically reviewed the manuscript and added intellectual content	critically reviewed the manuscript and added intellectual content	Wrote the paper	Writing - Review & Editing	YES
5310051	28196472	DL	2	conceived, organized and supervised the project	conceived, organized and supervised the project	Conceived and designed the experiments	Conceptualization|Project administration|Supervision	YES
5310051	28196472	RT	2	conducted the analysis	conducted the analysis	Performed the experiments	Investigation	YES
5310051	28196472	ZL	2	wrote the preliminary r code	wrote the preliminary r code	Wrote the paper	Software|Writing - Original Draft	YES
5310051	28196472	ZT	2	conceived, organized and supervised the project|conducted the analysis|drafted the manuscript	conceived, organized and supervised the project	Conceived and designed the experiments	Conceptualization|Project administration|Supervision	YES
5310051	28196472	ZT	2	conceived, organized and supervised the project|conducted the analysis|drafted the manuscript	conducted the analysis	Performed the experiments	Investigation	YES
5310051	28196472	ZT	2	conceived, organized and supervised the project|conducted the analysis|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4405589	25897758	AM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405589	25897758	AM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405589	25897758	AM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405589	25897758	AM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405589	25897758	JCW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405589	25897758	JCW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405589	25897758	JCW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405589	25897758	JCW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405589	25897758	JK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405589	25897758	JK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405589	25897758	JK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405589	25897758	JK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405589	25897758	PII	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405589	25897758	PII	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405589	25897758	PII	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6163468	30072586	G.G.	2	conceived the idea and wrote the paper	conceived the idea and wrote the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
6163468	30072586	L.S.N.	2	conceived the idea and wrote the paper	conceived the idea and wrote the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5524220	28761642	Abdelrahman Abdelaal	7	conception of idea and design, supervision, and review	conception of idea and design, supervision, and review	Conceived and designed the experiments	Conceptualization|Supervision	YES
5524220	28761642	Ammar Aleter	7	data collection, interpretation and review	data collection, interpretation and review	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5524220	28761642	Ayman El-Menyar	7	write up and review	write up and review	Wrote the paper	Writing - Review & Editing	YES
5524220	28761642	Fakhar Shahid	7	data collection, interpretation and review	data collection, interpretation and review	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5524220	28761642	Issam Al-Bozom	7	write up the pathology section and review	write up the pathology section and review	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5524220	28761642	Mahwish Khawar	7	data collection and review	data collection and review	Performed the experiments	Investigation	YES
5524220	28761642	Mohammed Rasoul Abunuwar	7	data collection, interpretation and review	data collection, interpretation and review	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5524220	28761642	Walid El Ansari	7	write up manuscript and review	write up manuscript and review	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5550838	28848582	CF	PLoS52	did the field trials	did the field trials	-	-	NO
5550838	28848582	DW	PLoS52	did the field trials	did the field trials	-	-	NO
5550838	28848582	DX	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5550838	28848582	LF	PLoS52	did the field trials	did the field trials	-	-	NO
5550838	28848582	LX	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5550838	28848582	QC	PLoS52	did the field trials	did the field trials	-	-	NO
5550838	28848582	SC	PLoS52	designed the experiment|wrote the paper	designed the experiment	Conceived and designed the experiments	Methodology	YES
5550838	28848582	SC	PLoS52	designed the experiment|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5550838	28848582	WW	PLoS52	did the field trials	did the field trials	-	-	NO
5550838	28848582	XC	PLoS52	did the field trials	did the field trials	-	-	NO
5550838	28848582	XT	PLoS52	performed the experiments|did the field trials|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5550838	28848582	XT	PLoS52	performed the experiments|did the field trials|wrote the paper	did the field trials	-	-	NO
5550838	28848582	XT	PLoS52	performed the experiments|did the field trials|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5550838	28848582	XX	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5550838	28848582	ZH	PLoS52	designed the experiment|wrote the paper	designed the experiment	Conceived and designed the experiments	Methodology	YES
5550838	28848582	ZH	PLoS52	designed the experiment|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3296187	22482058	C. A. Frankenberger	2	contributed equally to this work	contributed equally to this work	-	-	NO
3296187	22482058	E. Bevilacqua	2	contributed equally to this work	contributed equally to this work	-	-	NO
4928103	27357495	All authors	2	critically reviewed and approved the current version of the manuscript	critically reviewed and approved the current version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4928103	27357495	CLC	2	provided feedback on emerging findings from the qualitative study and reviewed and provided comments on manuscript drafts	provided feedback on emerging findings from the qualitative study and reviewed and provided comments on manuscript drafts	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4928103	27357495	HvR	2	provided feedback on emerging findings from the qualitative study and reviewed and provided comments on manuscript drafts	provided feedback on emerging findings from the qualitative study and reviewed and provided comments on manuscript drafts	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4928103	27357495	MAW	2	designed the qualitative research	designed the qualitative research	Conceived and designed the experiments	Methodology	YES
4928103	27357495	NCW	2	designed the qualitative research|led the data analytic process and wrote and revised the manuscript	designed the qualitative research	Conceived and designed the experiments	Methodology	YES
4928103	27357495	NCW	2	designed the qualitative research|led the data analytic process and wrote and revised the manuscript	led the data analytic process and wrote and revised the manuscript	Analyzed the data|Wrote the paper	Data curation|Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
4928103	27357495	RB	2	provided feedback on emerging findings from the qualitative study and reviewed and provided comments on manuscript drafts	provided feedback on emerging findings from the qualitative study and reviewed and provided comments on manuscript drafts	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5524222	28761640	Enas S. Ahmad	2	data collections, data analysis, writing	data collections, data analysis, writing	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation	YES
6163482	30158511	M.V.	2	conceived and designed the study|collected data and performed data analysis|were responsible for the provision of material and resources|participated in writing the article and approved the final version to be published	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6163482	30158511	M.V.	2	conceived and designed the study|collected data and performed data analysis|were responsible for the provision of material and resources|participated in writing the article and approved the final version to be published	collected data and performed data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6163482	30158511	M.V.	2	conceived and designed the study|collected data and performed data analysis|were responsible for the provision of material and resources|participated in writing the article and approved the final version to be published	were responsible for the provision of material and resources	Contributed reagents/materials/analysis tools	Resources	YES
6163482	30158511	M.V.	2	conceived and designed the study|collected data and performed data analysis|were responsible for the provision of material and resources|participated in writing the article and approved the final version to be published	participated in writing the article and approved the final version to be published	Wrote the paper	Writing - Original Draft	YES
6163482	30158511	S.A.	2	were responsible for the provision of material and resources|participated in writing the article and approved the final version to be published	were responsible for the provision of material and resources	Contributed reagents/materials/analysis tools	Resources	YES
6163482	30158511	S.A.	2	were responsible for the provision of material and resources|participated in writing the article and approved the final version to be published	participated in writing the article and approved the final version to be published	Wrote the paper	Writing - Original Draft	YES
6163482	30158511	S.J.	2	conceived and designed the study|collected data and performed data analysis|participated in writing the article and approved the final version to be published	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6163482	30158511	S.J.	2	conceived and designed the study|collected data and performed data analysis|participated in writing the article and approved the final version to be published	collected data and performed data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6163482	30158511	S.J.	2	conceived and designed the study|collected data and performed data analysis|participated in writing the article and approved the final version to be published	participated in writing the article and approved the final version to be published	Wrote the paper	Writing - Original Draft	YES
4930545	27370169	Both authors	2	contributed equally to the inception, design and writing of this piece and have read and approved the final version	contributed equally to the inception, design and writing of this piece and have read and approved the final version	Conceived and designed the experiments|Wrote the paper	-	YES
5524225	28761643	Argyrios Ioannidis	2	carried out and participate at the surgical excision and the manuscript demonstration	carried out and participate at the surgical excision and the manuscript demonstration	Performed the experiments	Investigation	YES
5524225	28761643	Ioannis Drikos	2	participated in the design of the study and helped to draft the manuscript	participated in the design of the study and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5524225	28761643	Konstantinos Alexiou	2	carried out and participate at the surgical excision and the manuscript demonstration|participated in the design of the study and helped to draft the manuscript	carried out and participate at the surgical excision and the manuscript demonstration	Performed the experiments	Investigation	YES
5524225	28761643	Konstantinos Alexiou	2	carried out and participate at the surgical excision and the manuscript demonstration|participated in the design of the study and helped to draft the manuscript	participated in the design of the study and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5524225	28761643	Maria Terzopoulou	2	carried out and participate at the surgical excision and the manuscript demonstration	carried out and participate at the surgical excision and the manuscript demonstration	Performed the experiments	Investigation	YES
5524225	28761643	Nikolaos Economou	2	carried out and participate at the surgical excision and the manuscript demonstration	carried out and participate at the surgical excision and the manuscript demonstration	Performed the experiments	Investigation	YES
5524225	28761643	Nikolaos Sikalias	2	carried out and participate at the surgical excision and the manuscript demonstration	carried out and participate at the surgical excision and the manuscript demonstration	Performed the experiments	Investigation	YES
4405590	25898318	ALS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405590	25898318	BBM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405590	25898318	BBM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405590	25898318	BBM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405590	25898318	BBM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405590	25898318	DWM	PLoS5	Contributed reagents/materials/analysis tools|Critically reviewed manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405590	25898318	DWM	PLoS5	Contributed reagents/materials/analysis tools|Critically reviewed manuscript	Critically reviewed manuscript	Wrote the paper	Writing - Review & Editing	YES
4405590	25898318	JS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405590	25898318	JS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405590	25898318	JS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405590	25898318	JS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405590	25898318	SLS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405590	25898318	TJS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5424673	28553467	All authors	2	discussed and analysed the data and commented on the manuscript	discussed and analysed the data and commented on the manuscript	Analyzed the data	Formal analysis	YES
5424673	28553467	C.S.	2	performed ec-stm	performed ec-stm	Performed the experiments	Investigation	YES
5424673	28553467	D.D.	2	performed stem	performed stem	Performed the experiments	Investigation	YES
5424673	28553467	E.A.P.	2	performed the measurements of the electrocatalytic activity and stability, the ga-xrd experiments, and wrote the first draft and designed the figures	performed the measurements of the electrocatalytic activity and stability, the ga-xrd experiments, and wrote the first draft and designed the figures	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Visualization|Writing - Original Draft	YES
5424673	28553467	I.C.	2	supervised the vacuum experiments and conceived the idea	supervised the vacuum experiments and conceived the idea	Conceived and designed the experiments	Conceptualization|Supervision	YES
5424673	28553467	I.E.L.S.	2	supervised the electrochemical measurements and co-wrote the first draft	supervised the electrochemical measurements and co-wrote the first draft	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Original Draft	YES
5424673	28553467	M.M.	2	performed the gas chromatography experiments	performed the gas chromatography experiments	Performed the experiments	Investigation	YES
5424673	28553467	S.H.	2	supervised the ec-stm experiments	supervised the ec-stm experiments	-	Supervision	YES
5424673	28553467	T.W.H.	2	supervised the stem	supervised the stem	-	Supervision	YES
5551076	28848568	DZ	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5551076	28848568	JX	PLoS52	provided experimental opinions and assistance	provided experimental opinions and assistance	-	-	NO
5551076	28848568	NU	PLoS52	provided experimental opinions and assistance	provided experimental opinions and assistance	-	-	NO
5551076	28848568	XP	PLoS52	provided experimental opinions and assistance	provided experimental opinions and assistance	-	-	NO
5551076	28848568	YHZ	PLoS52	performed the experiments|analyzed the data and wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5551076	28848568	YHZ	PLoS52	performed the experiments|analyzed the data and wrote the paper	analyzed the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5551076	28848568	YPZ	PLoS52	provided experimental opinions and assistance|performed the experiments	provided experimental opinions and assistance	-	-	NO
5551076	28848568	YPZ	PLoS52	provided experimental opinions and assistance|performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5310052	28202009	CAZ	2	carried out sequence analysis and designed it markers	carried out sequence analysis and designed it markers	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5310052	28202009	CPD	2	contributed to the development of the germplasm used in the experiments	contributed to the development of the germplasm used in the experiments	Performed the experiments	Investigation	YES
5310052	28202009	DKL	2	performed all experiments	performed all experiments	Performed the experiments	Investigation	YES
5310052	28202009	JD	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5310052	28202009	WHY	2	designed experimental plan|performed all experiments|wrote the manuscript	designed experimental plan	Conceived and designed the experiments	Methodology	YES
5310052	28202009	WHY	2	designed experimental plan|performed all experiments|wrote the manuscript	performed all experiments	Performed the experiments	Investigation	YES
5310052	28202009	WHY	2	designed experimental plan|performed all experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5310052	28202009	WXE	2	designed experimental plan|wrote the manuscript	designed experimental plan	Conceived and designed the experiments	Methodology	YES
5310052	28202009	WXE	2	designed experimental plan|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5310052	28202009	WYF	2	carried out sequence analysis and designed it markers	carried out sequence analysis and designed it markers	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5310052	28202009	XJ	2	designed experimental plan|carried out sequence analysis and designed it markers	designed experimental plan	Conceived and designed the experiments	Methodology	YES
5310052	28202009	XJ	2	designed experimental plan|carried out sequence analysis and designed it markers	carried out sequence analysis and designed it markers	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5310052	28202009	YCX	2	performed all experiments	performed all experiments	Performed the experiments	Investigation	YES
5310052	28202009	ZRH	2	contributed to the development of the germplasm used in the experiments	contributed to the development of the germplasm used in the experiments	Performed the experiments	Investigation	YES
5310052	28202009	ZSZ	2	managed the materials in the field	managed the materials in the field	-	-	NO
6163511	30081547	B.E.B.	CRediT	Conceptualization|Methodology|Formal analysis|Writing-original draft preparation|Writing-review & editing|Funding acquisition	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6163511	30081547	B.E.B.	CRediT	Conceptualization|Methodology|Formal analysis|Writing-original draft preparation|Writing-review & editing|Funding acquisition	Methodology	Performed the experiments	Methodology	YES
6163511	30081547	B.E.B.	CRediT	Conceptualization|Methodology|Formal analysis|Writing-original draft preparation|Writing-review & editing|Funding acquisition	Formal analysis	Analyzed the data	Formal analysis	YES
6163511	30081547	B.E.B.	CRediT	Conceptualization|Methodology|Formal analysis|Writing-original draft preparation|Writing-review & editing|Funding acquisition	Writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
6163511	30081547	B.E.B.	CRediT	Conceptualization|Methodology|Formal analysis|Writing-original draft preparation|Writing-review & editing|Funding acquisition	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6163511	30081547	B.E.B.	CRediT	Conceptualization|Methodology|Formal analysis|Writing-original draft preparation|Writing-review & editing|Funding acquisition	Funding acquisition	-	Funding acquisition	YES
6163511	30081547	J.M.T.	CRediT	Methodology|Writing-review & editing	Methodology	Performed the experiments	Methodology	YES
6163511	30081547	J.M.T.	CRediT	Methodology|Writing-review & editing	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6163511	30081547	K.C.K.	CRediT	Methodology|Writing-review & editing	Methodology	Performed the experiments	Methodology	YES
6163511	30081547	K.C.K.	CRediT	Methodology|Writing-review & editing	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6163511	30081547	M.P.D.	CRediT	Methodology|Writing-review & editing	Methodology	Performed the experiments	Methodology	YES
6163511	30081547	M.P.D.	CRediT	Methodology|Writing-review & editing	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6163511	30081547	T.D.W.	CRediT	Methodology|Writing-review & editing	Methodology	Performed the experiments	Methodology	YES
6163511	30081547	T.D.W.	CRediT	Methodology|Writing-review & editing	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6163511	30081547	T.L.R.	CRediT	Conceptualization|Methodology|Writing-original draft preparation|Writing-review & editing|Funding acquisition	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6163511	30081547	T.L.R.	CRediT	Conceptualization|Methodology|Writing-original draft preparation|Writing-review & editing|Funding acquisition	Methodology	Performed the experiments	Methodology	YES
6163511	30081547	T.L.R.	CRediT	Conceptualization|Methodology|Writing-original draft preparation|Writing-review & editing|Funding acquisition	Writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
6163511	30081547	T.L.R.	CRediT	Conceptualization|Methodology|Writing-original draft preparation|Writing-review & editing|Funding acquisition	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6163511	30081547	T.L.R.	CRediT	Conceptualization|Methodology|Writing-original draft preparation|Writing-review & editing|Funding acquisition	Funding acquisition	-	Funding acquisition	YES
4933795	27389256	CB	2	contributed to data analysis	contributed to data analysis	Analyzed the data	Formal analysis	YES
4933795	27389256	DWF	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
4933795	27389256	JWP	2	designed the study|contributed to clinical management and follow-up	designed the study	Conceived and designed the experiments	Methodology	YES
4933795	27389256	JWP	2	designed the study|contributed to clinical management and follow-up	contributed to clinical management and follow-up	-	-	NO
4933795	27389256	LK	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
4933795	27389256	LKR	2	designed the study|contributed to data analysis|with substantive revisions and input from all authors	designed the study	Conceived and designed the experiments	Methodology	YES
4933795	27389256	LKR	2	designed the study|contributed to data analysis|with substantive revisions and input from all authors	contributed to data analysis	Analyzed the data	Formal analysis	YES
4933795	27389256	LKR	2	designed the study|contributed to data analysis|with substantive revisions and input from all authors	with substantive revisions and input from all authors	Wrote the paper	Writing - Review & Editing	YES
4933795	27389256	MLM	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
4933795	27389256	MRL	2	contributed to data analysis	contributed to data analysis	Analyzed the data	Formal analysis	YES
4933795	27389256	RB	2	contributed to clinical management and follow-up	contributed to clinical management and follow-up	-	-	NO
4933795	27389256	RV	2	contributed to clinical management and follow-up	contributed to clinical management and follow-up	-	-	NO
4933795	27389256	VR	2	contributed to clinical management and follow-up	contributed to clinical management and follow-up	-	-	NO
4933795	27389256	WDJ	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
4405591	25897661	AK	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405591	25897661	AMN	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405591	25897661	EVM	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405591	25897661	EVM	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405591	25897661	JAC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405591	25897661	JAC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405591	25897661	JAC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405591	25897661	JAC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405591	25897661	KVV	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405591	25897661	KVV	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405591	25897661	RC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405591	25897661	RC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405591	25897661	RC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405591	25897661	RC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405591	25897661	RLL	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405591	25897661	RLL	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405591	25897661	RLL	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405591	25897661	SK	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405591	25897661	SK	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405591	25897661	YCM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405591	25897661	YCM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405591	25897661	YCM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5551093	28848566	AD	2	designed this study|produced and treated the plant material in the greenhouse and carried out the plant phenotype rating|performed the molecular biology analyses|analyzed the data and wrote the manuscript	designed this study	Conceived and designed the experiments	Methodology	YES
5551093	28848566	AD	2	designed this study|produced and treated the plant material in the greenhouse and carried out the plant phenotype rating|performed the molecular biology analyses|analyzed the data and wrote the manuscript	produced and treated the plant material in the greenhouse and carried out the plant phenotype rating	Performed the experiments	Investigation	YES
5551093	28848566	AD	2	designed this study|produced and treated the plant material in the greenhouse and carried out the plant phenotype rating|performed the molecular biology analyses|analyzed the data and wrote the manuscript	performed the molecular biology analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5551093	28848566	AD	2	designed this study|produced and treated the plant material in the greenhouse and carried out the plant phenotype rating|performed the molecular biology analyses|analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5551093	28848566	All authors	2	read and approved the manuscript	read and approved the manuscript	-	-	NO
5551093	28848566	CD	2	designed this study|analyzed the data and wrote the manuscript|supervised the project	designed this study	Conceived and designed the experiments	Methodology	YES
5551093	28848566	CD	2	designed this study|analyzed the data and wrote the manuscript|supervised the project	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5551093	28848566	CD	2	designed this study|analyzed the data and wrote the manuscript|supervised the project	supervised the project	-	Supervision	YES
5551093	28848566	DD	2	produced and treated the plant material in the greenhouse and carried out the plant phenotype rating|performed the molecular biology analyses	produced and treated the plant material in the greenhouse and carried out the plant phenotype rating	Performed the experiments	Investigation	YES
5551093	28848566	DD	2	produced and treated the plant material in the greenhouse and carried out the plant phenotype rating|performed the molecular biology analyses	performed the molecular biology analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5551093	28848566	FP	2	performed the molecular biology analyses	performed the molecular biology analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5524314	28761644	P Joseph	2	examined the histopathological slides for the case	examined the histopathological slides for the case	Performed the experiments	Investigation	YES
5524314	28761644	Surej Kumar	2	is responsible for concept and definition of intellectual content	is responsible for concept and definition of intellectual content	Conceived and designed the experiments	Conceptualization	YES
4947868	27424601	All authors	2	have reviewed and approved the article	have reviewed and approved the article	Wrote the paper	Writing - Review & Editing	YES
5310062	28201993	AL	2	conducted the molecular work and data analysis	conducted the molecular work and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5310062	28201993	DC	2	contributed to the development of the project	contributed to the development of the project	-	-	NO
5310062	28201993	DG	2	conceived and designed the study|drafted the manuscript|coordinated the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5310062	28201993	DG	2	conceived and designed the study|drafted the manuscript|coordinated the study	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5310062	28201993	DG	2	conceived and designed the study|drafted the manuscript|coordinated the study	coordinated the study	-	Project administration	YES
5310062	28201993	ER	2	conceived and designed the study|drafted the manuscript|coordinated the study|contributed to the development of the project	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5310062	28201993	ER	2	conceived and designed the study|drafted the manuscript|coordinated the study|contributed to the development of the project	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5310062	28201993	ER	2	conceived and designed the study|drafted the manuscript|coordinated the study|contributed to the development of the project	coordinated the study	-	Project administration	YES
5310062	28201993	ER	2	conceived and designed the study|drafted the manuscript|coordinated the study|contributed to the development of the project	contributed to the development of the project	-	-	NO
5310062	28201993	HK	2	contributed to the development of the project	contributed to the development of the project	-	-	NO
5310062	28201993	IN	2	conceived and designed the study|conducted the molecular work and data analysis|drafted the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5310062	28201993	IN	2	conceived and designed the study|conducted the molecular work and data analysis|drafted the manuscript	conducted the molecular work and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5310062	28201993	IN	2	conceived and designed the study|conducted the molecular work and data analysis|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5310062	28201993	LS	2	conducted the molecular work and data analysis	conducted the molecular work and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5310062	28201993	NGS	2	reads and complete whole genome sequences	reads and complete whole genome sequences	Performed the experiments	Investigation	YES
5310062	28201993	PJF	2	conceived and designed the study|conducted the molecular work and data analysis|drafted the manuscript|coordinated the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5310062	28201993	PJF	2	conceived and designed the study|conducted the molecular work and data analysis|drafted the manuscript|coordinated the study	conducted the molecular work and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5310062	28201993	PJF	2	conceived and designed the study|conducted the molecular work and data analysis|drafted the manuscript|coordinated the study	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5310062	28201993	PJF	2	conceived and designed the study|conducted the molecular work and data analysis|drafted the manuscript|coordinated the study	coordinated the study	-	Project administration	YES
5310062	28201993	SRH	2	conducted the molecular work and data analysis	conducted the molecular work and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5310062	28201993	ZD	2	contributed to the development of the project	contributed to the development of the project	-	-	NO
6163628	30046021	A.A.	CRediT	Methodology|Writing-review & editing|Visualization	Methodology	Performed the experiments	Methodology	YES
6163628	30046021	A.A.	CRediT	Methodology|Writing-review & editing|Visualization	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6163628	30046021	A.A.	CRediT	Methodology|Writing-review & editing|Visualization	Visualization	Analyzed the data	Visualization	YES
6163628	30046021	M.A.	CRediT	Conceptualization|Methodology|Software|Validation|Investigation|Resources|Data curation|Writing-original draft preparation|Visualization	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6163628	30046021	M.A.	CRediT	Conceptualization|Methodology|Software|Validation|Investigation|Resources|Data curation|Writing-original draft preparation|Visualization	Methodology	Performed the experiments	Methodology	YES
6163628	30046021	M.A.	CRediT	Conceptualization|Methodology|Software|Validation|Investigation|Resources|Data curation|Writing-original draft preparation|Visualization	Software	Contributed reagents/materials/analysis tools	Software	YES
6163628	30046021	M.A.	CRediT	Conceptualization|Methodology|Software|Validation|Investigation|Resources|Data curation|Writing-original draft preparation|Visualization	Validation	Performed the experiments	Validation	YES
6163628	30046021	M.A.	CRediT	Conceptualization|Methodology|Software|Validation|Investigation|Resources|Data curation|Writing-original draft preparation|Visualization	Investigation	Performed the experiments	Investigation	YES
6163628	30046021	M.A.	CRediT	Conceptualization|Methodology|Software|Validation|Investigation|Resources|Data curation|Writing-original draft preparation|Visualization	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6163628	30046021	M.A.	CRediT	Conceptualization|Methodology|Software|Validation|Investigation|Resources|Data curation|Writing-original draft preparation|Visualization	Data curation	Analyzed the data	Data curation	YES
6163628	30046021	M.A.	CRediT	Conceptualization|Methodology|Software|Validation|Investigation|Resources|Data curation|Writing-original draft preparation|Visualization	Writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
6163628	30046021	M.A.	CRediT	Conceptualization|Methodology|Software|Validation|Investigation|Resources|Data curation|Writing-original draft preparation|Visualization	Visualization	Analyzed the data	Visualization	YES
6163628	30046021	M.Q.	CRediT	Data curation|Writing-review & editing	Data curation	Analyzed the data	Data curation	YES
6163628	30046021	M.Q.	CRediT	Data curation|Writing-review & editing	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6163628	30046021	O.Y.	CRediT	Formal analysis|Writing-review & editing	Formal analysis	Analyzed the data	Formal analysis	YES
6163628	30046021	O.Y.	CRediT	Formal analysis|Writing-review & editing	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6163628	30046021	S.I.	CRediT	Conceptualization|Methodology|Software|Validation|Formal analysis|Data curation|Writing-review & editing|Visualization|Supervision|Project administration	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6163628	30046021	S.I.	CRediT	Conceptualization|Methodology|Software|Validation|Formal analysis|Data curation|Writing-review & editing|Visualization|Supervision|Project administration	Methodology	Performed the experiments	Methodology	YES
6163628	30046021	S.I.	CRediT	Conceptualization|Methodology|Software|Validation|Formal analysis|Data curation|Writing-review & editing|Visualization|Supervision|Project administration	Software	Contributed reagents/materials/analysis tools	Software	YES
6163628	30046021	S.I.	CRediT	Conceptualization|Methodology|Software|Validation|Formal analysis|Data curation|Writing-review & editing|Visualization|Supervision|Project administration	Validation	Performed the experiments	Validation	YES
6163628	30046021	S.I.	CRediT	Conceptualization|Methodology|Software|Validation|Formal analysis|Data curation|Writing-review & editing|Visualization|Supervision|Project administration	Formal analysis	Analyzed the data	Formal analysis	YES
6163628	30046021	S.I.	CRediT	Conceptualization|Methodology|Software|Validation|Formal analysis|Data curation|Writing-review & editing|Visualization|Supervision|Project administration	Data curation	Analyzed the data	Data curation	YES
6163628	30046021	S.I.	CRediT	Conceptualization|Methodology|Software|Validation|Formal analysis|Data curation|Writing-review & editing|Visualization|Supervision|Project administration	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6163628	30046021	S.I.	CRediT	Conceptualization|Methodology|Software|Validation|Formal analysis|Data curation|Writing-review & editing|Visualization|Supervision|Project administration	Visualization	Analyzed the data	Visualization	YES
6163628	30046021	S.I.	CRediT	Conceptualization|Methodology|Software|Validation|Formal analysis|Data curation|Writing-review & editing|Visualization|Supervision|Project administration	Supervision	-	Supervision	YES
6163628	30046021	S.I.	CRediT	Conceptualization|Methodology|Software|Validation|Formal analysis|Data curation|Writing-review & editing|Visualization|Supervision|Project administration	Project administration	-	Project administration	YES
4491375	26180779	Carlos R. Camara-Lemarroy	2	served as the principal investigators and contributed to study design, data collection, and paper preparation	served as the principal investigators and contributed to study design, data collection, and paper preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Funding acquisition|Investigation|Methodology|Resources	YES
4491375	26180779	Enrique Caballero	2	contributed to the study design and coordination and helped draft the paper	contributed to the study design and coordination and helped draft the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft	YES
4491375	26180779	Manuel Gonzalez-Chavez	2	contributed to study design, data collection, and paper preparation	contributed to study design, data collection, and paper preparation	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources	YES
4491375	26180779	Rene Rodriguez-Gutierrez	2	served as the principal investigators and contributed to study design, data collection, and paper preparation	served as the principal investigators and contributed to study design, data collection, and paper preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Funding acquisition|Investigation|Methodology|Resources	YES
4405592	25898012	CZ	CRediT	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405592	25898012	CZ	CRediT	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4405592	25898012	JGZ	CRediT	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405592	25898012	MML	CRediT	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405592	25898012	SPH	CRediT	supervision	supervision	-	Supervision	YES
4405592	25898012	SSZ	CRediT	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405592	25898012	SSZ	CRediT	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405592	25898012	SSZ	CRediT	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405592	25898012	XHL	CRediT	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405592	25898012	XSH	CRediT	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4405592	25898012	YZP	CRediT	supervision	supervision	-	Supervision	YES
4405592	25898012	ZBY	CRediT	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5552701	28848588	FG	PLoS52	performed the experiment	performed the experiment	Performed the experiments	Investigation	YES
5552701	28848588	HJ	PLoS52	performed the experiment	performed the experiment	Performed the experiments	Investigation	YES
5552701	28848588	JL	PLoS52	performed the experiment	performed the experiment	Performed the experiments	Investigation	YES
5552701	28848588	SZ	PLoS52	performed the experiment	performed the experiment	Performed the experiments	Investigation	YES
5552701	28848588	WW	PLoS52	performed the experiment|wrote the paper	performed the experiment	Performed the experiments	Investigation	YES
5552701	28848588	WW	PLoS52	performed the experiment|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5552701	28848588	XX	PLoS52	designed the experiment|wrote the paper	designed the experiment	Conceived and designed the experiments	Methodology	YES
5552701	28848588	XX	PLoS52	designed the experiment|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5552701	28848588	YQ	PLoS52	designed the experiment	designed the experiment	Conceived and designed the experiments	Methodology	YES
5552701	28848588	ZH	PLoS52	designed the experiment|wrote the paper	designed the experiment	Conceived and designed the experiments	Methodology	YES
5552701	28848588	ZH	PLoS52	designed the experiment|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4949308	27431475	AR	2	designed the study and developed the methodology|performed the literature review|wrote the manuscript	designed the study and developed the methodology	Conceived and designed the experiments|Performed the experiments	Methodology	YES
4949308	27431475	AR	2	designed the study and developed the methodology|performed the literature review|wrote the manuscript	performed the literature review	Performed the experiments	Formal analysis|Investigation	YES
4949308	27431475	AR	2	designed the study and developed the methodology|performed the literature review|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4949308	27431475	JS	2	designed the study and developed the methodology|wrote the manuscript	designed the study and developed the methodology	Conceived and designed the experiments|Performed the experiments	Methodology	YES
4949308	27431475	JS	2	designed the study and developed the methodology|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4949308	27431475	MD	2	designed the study and developed the methodology|wrote the manuscript	designed the study and developed the methodology	Conceived and designed the experiments|Performed the experiments	Methodology	YES
4949308	27431475	MD	2	designed the study and developed the methodology|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5526469	28765784	Edoardo Raposio	2	study design	study design	Conceived and designed the experiments	Methodology	YES
5526469	28765784	Mariana Pesce	2	data collections	data collections	Performed the experiments	Investigation	YES
5526469	28765784	Pierluigi Santi	2	data collections	data collections	Performed the experiments	Investigation	YES
5310065	28196482	AAYL	2	performed the experiment, processed the samples, performed the analyses, and drafted the manuscript	performed the experiment, processed the samples, performed the analyses, and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Formal analysis|Investigation|Writing - Original Draft	YES
5310065	28196482	AOT	2	participated in the design and coordination of the study, and provided advice and comments to help draft the manuscript	participated in the design and coordination of the study, and provided advice and comments to help draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft	YES
5310065	28196482	DAC	2	participated in the design and coordination of the study, and provided advice and comments to help draft the manuscript	participated in the design and coordination of the study, and provided advice and comments to help draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft	YES
5310065	28196482	KBH	2	participated in the design and coordination of the study, and provided advice and comments to help draft the manuscript	participated in the design and coordination of the study, and provided advice and comments to help draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft	YES
5310065	28196482	RT	2	participated in the design and coordination of the study, and provided advice and comments to help draft the manuscript	participated in the design and coordination of the study, and provided advice and comments to help draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft	YES
5310065	28196482	ZL	2	processed the raw sequences of the transcriptome, performed the assembly, annotation, and differential gene expression analysis	processed the raw sequences of the transcriptome, performed the assembly, annotation, and differential gene expression analysis	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
6163684	30103480	A.C.	2	developed the study|were responsible for data analysis and interpretation	developed the study	-	-	NO
6163684	30103480	A.C.	2	developed the study|were responsible for data analysis and interpretation	were responsible for data analysis and interpretation	Analyzed the data	Formal analysis	YES
6163684	30103480	All authors	2	contributed to the preparation of the final manuscript	contributed to the preparation of the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6163684	30103480	D.B.	2	developed the study|were responsible for data analysis and interpretation	developed the study	-	-	NO
6163684	30103480	D.B.	2	developed the study|were responsible for data analysis and interpretation	were responsible for data analysis and interpretation	Analyzed the data	Formal analysis	YES
6163684	30103480	H.M.	2	developed the study	developed the study	-	-	NO
6163684	30103480	S.S.	2	were responsible for data analysis and interpretation	were responsible for data analysis and interpretation	Analyzed the data	Formal analysis	YES
4405593	25898278	JJW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405593	25898278	JJW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405593	25898278	JJW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405593	25898278	JJW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405593	25898278	JJW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405593	25898278	LPS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405593	25898278	LPS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405593	25898278	LPS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405593	25898278	SKW	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405593	25898278	SKW	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405593	25898278	SKW	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5552710	28848595	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5552710	28848595	JW	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|contributed to the writing of the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5552710	28848595	JW	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|contributed to the writing of the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5552710	28848595	JW	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|contributed to the writing of the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5552710	28848595	JW	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|contributed to the writing of the manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5552710	28848595	JZ	PLoS52	performed the experiments|analyzed the data|contributed to the writing of the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5552710	28848595	JZ	PLoS52	performed the experiments|analyzed the data|contributed to the writing of the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5552710	28848595	JZ	PLoS52	performed the experiments|analyzed the data|contributed to the writing of the manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5552710	28848595	LW	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5552710	28848595	SW	PLoS52	conceived and designed the experiments|contributed to the writing of the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5552710	28848595	SW	PLoS52	conceived and designed the experiments|contributed to the writing of the manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5526470	28765785	Javier Rojas-Mendez	7	He is a surgery professor, he monitorized the work that was being done. He recollected data, revised the manuscript, and he wrote part of the manuscript	He is a surgery professor, he monitorized the work that was being done. He recollected data, revised the manuscript, and he wrote part of the manuscript	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
5526470	28765785	Lucas O. Tijerina-Gomez	7	He is the surgeon in charge of the case, he checked the work was being well done, he made the final approval of the manuscript. He wrote part of the manuscript. He recollected data	He is the surgeon in charge of the case, he checked the work was being well done, he made the final approval of the manuscript. He wrote part of the manuscript. He recollected data	Performed the experiments|Wrote the paper	Data curation|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5526470	28765785	Mauricio Gonzalez- Urquijo	7	He is a first year general surgery resident. He was the leader of the work, he design the case report. He recollected data, and wrote the manuscript	He is a first year general surgery resident. He was the leader of the work, he design the case report. He recollected data, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Original Draft	YES
4949309	27431470	ASS	2	designed the protocol, wrote the first manuscript draft, coordinated and incorporated input from co-authors and completed the manuscript	designed the protocol, wrote the first manuscript draft, coordinated and incorporated input from co-authors and completed the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft	YES
4949309	27431470	CF	2	provided substantial comments to the earlier drafts	provided substantial comments to the earlier drafts	Wrote the paper	Writing - Original Draft	YES
4949309	27431470	GdlI	2	provided substantial comments to the earlier drafts	provided substantial comments to the earlier drafts	Wrote the paper	Writing - Original Draft	YES
4949309	27431470	RM	2	provided substantial comments to the earlier drafts	provided substantial comments to the earlier drafts	Wrote the paper	Writing - Original Draft	YES
4949309	27431470	SE	2	designed the protocol, wrote the first manuscript draft, coordinated and incorporated input from co-authors and completed the manuscript	designed the protocol, wrote the first manuscript draft, coordinated and incorporated input from co-authors and completed the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft	YES
5310086	28196466	AK	PLoS5	Conceived and designed the experiments|Analyzed sequence data|Drafted the manuscript|Revised the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5310086	28196466	AK	PLoS5	Conceived and designed the experiments|Analyzed sequence data|Drafted the manuscript|Revised the manuscript	Analyzed sequence data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5310086	28196466	AK	PLoS5	Conceived and designed the experiments|Analyzed sequence data|Drafted the manuscript|Revised the manuscript	Drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5310086	28196466	AK	PLoS5	Conceived and designed the experiments|Analyzed sequence data|Drafted the manuscript|Revised the manuscript	Revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5310086	28196466	ANRC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5310086	28196466	EM	PLoS5	Analyzed sequence data	Analyzed sequence data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5310086	28196466	FM	PLoS5	Conceived and designed the experiments|Revised the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5310086	28196466	FM	PLoS5	Conceived and designed the experiments|Revised the manuscript	Revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5310086	28196466	MDC	PLoS5	Conceived and designed the experiments|Revised the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5310086	28196466	MDC	PLoS5	Conceived and designed the experiments|Revised the manuscript	Revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5310086	28196466	MFP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed sequence data|Drafted the manuscript|Revised the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5310086	28196466	MFP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed sequence data|Drafted the manuscript|Revised the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
5310086	28196466	MFP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed sequence data|Drafted the manuscript|Revised the manuscript	Analyzed sequence data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5310086	28196466	MFP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed sequence data|Drafted the manuscript|Revised the manuscript	Drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5310086	28196466	MFP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed sequence data|Drafted the manuscript|Revised the manuscript	Revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5310086	28196466	SHB	PLoS5	Revised the manuscript	Revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5310086	28196466	TAC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4405594	25898205	KN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405594	25898205	KN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405594	25898205	KN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405594	25898205	KN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405594	25898205	KS	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4405594	25898205	MM	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4405594	25898205	NNK	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405594	25898205	TK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405594	25898205	TK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405594	25898205	TK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405594	25898205	YT	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
6163710	30223544	B.H.S.	CRediT	Conceptualization|Formal analysis|Investigation|Methodology|Writing--review and editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6163710	30223544	B.H.S.	CRediT	Conceptualization|Formal analysis|Investigation|Methodology|Writing--review and editing	Formal analysis	Analyzed the data	Formal analysis	YES
6163710	30223544	B.H.S.	CRediT	Conceptualization|Formal analysis|Investigation|Methodology|Writing--review and editing	Investigation	Performed the experiments	Investigation	YES
6163710	30223544	B.H.S.	CRediT	Conceptualization|Formal analysis|Investigation|Methodology|Writing--review and editing	Methodology	Performed the experiments	Methodology	YES
6163710	30223544	B.H.S.	CRediT	Conceptualization|Formal analysis|Investigation|Methodology|Writing--review and editing	Writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6163710	30223544	J.M.L.	CRediT	Conceptualization|Formal analysis|Investigation|Methodology|Writing--review and editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6163710	30223544	J.M.L.	CRediT	Conceptualization|Formal analysis|Investigation|Methodology|Writing--review and editing	Formal analysis	Analyzed the data	Formal analysis	YES
6163710	30223544	J.M.L.	CRediT	Conceptualization|Formal analysis|Investigation|Methodology|Writing--review and editing	Investigation	Performed the experiments	Investigation	YES
6163710	30223544	J.M.L.	CRediT	Conceptualization|Formal analysis|Investigation|Methodology|Writing--review and editing	Methodology	Performed the experiments	Methodology	YES
6163710	30223544	J.M.L.	CRediT	Conceptualization|Formal analysis|Investigation|Methodology|Writing--review and editing	Writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6163710	30223544	N.C.	CRediT	Conceptualization|Data curation|Formal analysis|Investigation|Methodology|Project administration|Resources|Validation|Writing--original draft|Writing--review and editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6163710	30223544	N.C.	CRediT	Conceptualization|Data curation|Formal analysis|Investigation|Methodology|Project administration|Resources|Validation|Writing--original draft|Writing--review and editing	Data curation	Analyzed the data	Data curation	YES
6163710	30223544	N.C.	CRediT	Conceptualization|Data curation|Formal analysis|Investigation|Methodology|Project administration|Resources|Validation|Writing--original draft|Writing--review and editing	Formal analysis	Analyzed the data	Formal analysis	YES
6163710	30223544	N.C.	CRediT	Conceptualization|Data curation|Formal analysis|Investigation|Methodology|Project administration|Resources|Validation|Writing--original draft|Writing--review and editing	Investigation	Performed the experiments	Investigation	YES
6163710	30223544	N.C.	CRediT	Conceptualization|Data curation|Formal analysis|Investigation|Methodology|Project administration|Resources|Validation|Writing--original draft|Writing--review and editing	Methodology	Performed the experiments	Methodology	YES
6163710	30223544	N.C.	CRediT	Conceptualization|Data curation|Formal analysis|Investigation|Methodology|Project administration|Resources|Validation|Writing--original draft|Writing--review and editing	Project administration	-	Project administration	YES
6163710	30223544	N.C.	CRediT	Conceptualization|Data curation|Formal analysis|Investigation|Methodology|Project administration|Resources|Validation|Writing--original draft|Writing--review and editing	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6163710	30223544	N.C.	CRediT	Conceptualization|Data curation|Formal analysis|Investigation|Methodology|Project administration|Resources|Validation|Writing--original draft|Writing--review and editing	Validation	Performed the experiments	Validation	YES
6163710	30223544	N.C.	CRediT	Conceptualization|Data curation|Formal analysis|Investigation|Methodology|Project administration|Resources|Validation|Writing--original draft|Writing--review and editing	Writing--original draft	Wrote the paper	Writing - Original Draft	YES
6163710	30223544	N.C.	CRediT	Conceptualization|Data curation|Formal analysis|Investigation|Methodology|Project administration|Resources|Validation|Writing--original draft|Writing--review and editing	Writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
5536384	28794872	Data Collection	2	data analysis	data analysis	Analyzed the data	Formal analysis	YES
5552711	28848597	ARK	2	revised manuscript	revised manuscript	Wrote the paper	Writing - Review & Editing	YES
5552711	28848597	All authors	2	made contribution to the experiment work and manuscript write up|made contribution to the approval of the final version of the manuscript to be published and agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	made contribution to the experiment work and manuscript write up	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5552711	28848597	All authors	2	made contribution to the experiment work and manuscript write up|made contribution to the approval of the final version of the manuscript to be published and agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	made contribution to the approval of the final version of the manuscript to be published and agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	-	-	NO
5552711	28848597	BDG	2	revised manuscript	revised manuscript	Wrote the paper	Writing - Review & Editing	YES
5552711	28848597	FM	2	made contribution to the design of the work, interpretation of data and critically revision of the manuscript	made contribution to the design of the work, interpretation of data and critically revision of the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
5552711	28848597	LZ	2	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5552711	28848597	PL	2	made contribution to the design of the work, interpretation of data and critically revision of the manuscript	made contribution to the design of the work, interpretation of data and critically revision of the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
5552711	28848597	RNUR	2	made substantial contribution to the design of the work, acquisition, analysis, and interpretation of data and drafting the manuscript	made substantial contribution to the design of the work, acquisition, analysis, and interpretation of data and drafting the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft	YES
5552711	28848597	YY	2	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
4949310	27431465	AK	2	supported the implementation of the studies, as well as supporting data cleaning processes and interpretation of the data	supported the implementation of the studies, as well as supporting data cleaning processes and interpretation of the data	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
4949310	27431465	All authors	2	contributed substantially to either the study design, data collection or analysis or interpretation of data	contributed substantially to either the study design, data collection or analysis or interpretation of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Methodology|Resources	YES
4949310	27431465	BL	2	supported the implementation of the studies, as well as supporting data cleaning processes and interpretation of the data	supported the implementation of the studies, as well as supporting data cleaning processes and interpretation of the data	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
4949310	27431465	FMD	2	supported the implementation of the studies, as well as supporting data cleaning processes and interpretation of the data	supported the implementation of the studies, as well as supporting data cleaning processes and interpretation of the data	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
4949310	27431465	PAMAC	2	in burkina faso and supported the manuscript development by providing important guidance	in burkina faso and supported the manuscript development by providing important guidance	-	Supervision	YES
4949310	27431465	SB	2	conceptualized the study designs and monitored study stages in all countries, as well as giving guidance on the analysis and being involved throughout the manuscript development	conceptualized the study designs and monitored study stages in all countries, as well as giving guidance on the analysis and being involved throughout the manuscript development	Conceived and designed the experiments	Conceptualization|Methodology|Supervision	YES
4949310	27431465	SS	2	led the analysis and writing of the manuscript	led the analysis and writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
4949310	27431465	West African	2	nations, which resulted in multiple collaborators	nations, which resulted in multiple collaborators	-	-	NO
5310122	28196526	EGR	PLoS52	conducted the experiments, analyzed the data and wrote the manuscript	conducted the experiments, analyzed the data and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5310122	28196526	GL	PLoS52	conceived the study, participated in the study design and wrote the manuscript	conceived the study, participated in the study design and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
5310122	28196526	JMG	PLoS52	conceived the study, participated in the study design and wrote the manuscript	conceived the study, participated in the study design and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
5310122	28196526	LP	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5310122	28196526	MM	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5552712	28848593	AE-F	2	helped with laboratory work	helped with laboratory work	Performed the experiments	Investigation	YES
5552712	28848593	All authors	2	reviewed the manuscript and agreed on its content	reviewed the manuscript and agreed on its content	Wrote the paper	Writing - Review & Editing	YES
5552712	28848593	RS	2	conceived and designed the study|wrote the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5552712	28848593	RS	2	conceived and designed the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5552712	28848593	XH	2	conceived and designed the study|wrote the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5552712	28848593	XH	2	conceived and designed the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4405609	25897838	AK	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4405609	25897838	AK	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4405609	25897838	AV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405609	25897838	AV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4405609	25897838	AV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405609	25897838	AZS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4405609	25897838	AZS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4405609	25897838	BR	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405609	25897838	BR	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405609	25897838	DB	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4405609	25897838	DD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405609	25897838	DD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4405609	25897838	DD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4405609	25897838	DK	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4405609	25897838	JS	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4405609	25897838	MHP	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4405609	25897838	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405609	25897838	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405609	25897838	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405609	25897838	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405609	25897838	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405609	25897838	PS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405609	25897838	PS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405609	25897838	PS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405609	25897838	PS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405609	25897838	SS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405609	25897838	SS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405609	25897838	SS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405609	25897838	SS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4491379	26180796	Agata Bednarek	2	contributed to interpretation of data	contributed to interpretation of data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
4491379	26180796	All the authors	2	listed have contributed substantially to the paper	listed have contributed substantially to the paper	-	-	NO
4491379	26180796	Elzbieta Skorupska	2	contributed to the conception and design of the work, acquisition of data, interpretation of data and drafting the paper	contributed to the conception and design of the work, acquisition of data, interpretation of data and drafting the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Resources|Writing - Original Draft	YES
4491379	26180796	Jaroslaw Zawadzinski	2	helped with acquisition of data, analysis of data, and drafting the paper	helped with acquisition of data, analysis of data, and drafting the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4491379	26180796	Wlodzimierz Samborski	2	helped with final approval of the version to be published	helped with final approval of the version to be published	-	-	NO
5310271	28198669	JL	2	developed the method	developed the method	Performed the experiments	Methodology	YES
5310271	28198669	QY	2	initiated the project|developed the method|implemented the experiments|wrote the manuscript with inputs from all authors	initiated the project	Conceived and designed the experiments	Conceptualization	YES
5310271	28198669	QY	2	initiated the project|developed the method|implemented the experiments|wrote the manuscript with inputs from all authors	developed the method	Performed the experiments	Methodology	YES
5310271	28198669	QY	2	initiated the project|developed the method|implemented the experiments|wrote the manuscript with inputs from all authors	implemented the experiments	Performed the experiments	Investigation	YES
5310271	28198669	QY	2	initiated the project|developed the method|implemented the experiments|wrote the manuscript with inputs from all authors	wrote the manuscript with inputs from all authors	Wrote the paper	Writing - Original Draft	YES
5310271	28198669	XZ	2	initiated the project|wrote the manuscript with inputs from all authors	initiated the project	Conceived and designed the experiments	Conceptualization	YES
5310271	28198669	XZ	2	initiated the project|wrote the manuscript with inputs from all authors	wrote the manuscript with inputs from all authors	Wrote the paper	Writing - Original Draft	YES
5310271	28198669	YH	2	wrote the codes and analyzed the algorithmatic complexity|implemented the experiments	wrote the codes and analyzed the algorithmatic complexity	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Software|Writing - Original Draft	YES
5310271	28198669	YH	2	wrote the codes and analyzed the algorithmatic complexity|implemented the experiments	implemented the experiments	Performed the experiments	Investigation	YES
6163764	30036982	A.B.	CRediT	Formal analysis|Writing--original draft preparation	Formal analysis	Analyzed the data	Formal analysis	YES
6163764	30036982	A.B.	CRediT	Formal analysis|Writing--original draft preparation	Writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6163764	30036982	C.D.C.	CRediT	Methodology|Investigation|Data curation|Writing--original draft preparation	Methodology	Performed the experiments	Methodology	YES
6163764	30036982	C.D.C.	CRediT	Methodology|Investigation|Data curation|Writing--original draft preparation	Investigation	Performed the experiments	Investigation	YES
6163764	30036982	C.D.C.	CRediT	Methodology|Investigation|Data curation|Writing--original draft preparation	Data curation	Analyzed the data	Data curation	YES
6163764	30036982	C.D.C.	CRediT	Methodology|Investigation|Data curation|Writing--original draft preparation	Writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6163764	30036982	E.B.	CRediT	Methodology|Formal analysis|Writing--original draft preparation	Methodology	Performed the experiments	Methodology	YES
6163764	30036982	E.B.	CRediT	Methodology|Formal analysis|Writing--original draft preparation	Formal analysis	Analyzed the data	Formal analysis	YES
6163764	30036982	E.B.	CRediT	Methodology|Formal analysis|Writing--original draft preparation	Writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6163764	30036982	F.W.	CRediT	Conceptualization|Methodology|Writing--original draft preparation	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6163764	30036982	F.W.	CRediT	Conceptualization|Methodology|Writing--original draft preparation	Methodology	Performed the experiments	Methodology	YES
6163764	30036982	F.W.	CRediT	Conceptualization|Methodology|Writing--original draft preparation	Writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6163764	30036982	J.B.	CRediT	Conceptualization|Methodology|Writing--original draft preparation	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6163764	30036982	J.B.	CRediT	Conceptualization|Methodology|Writing--original draft preparation	Methodology	Performed the experiments	Methodology	YES
6163764	30036982	J.B.	CRediT	Conceptualization|Methodology|Writing--original draft preparation	Writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
4949311	27431466	AIS	2	conceived and designed the analysis|drafted the manuscript	conceived and designed the analysis	Conceived and designed the experiments	Conceptualization	YES
4949311	27431466	AIS	2	conceived and designed the analysis|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4949311	27431466	All authors	2	contributed to interpreting data and revising the manuscript and have read and approved the final version	contributed to interpreting data and revising the manuscript and have read and approved the final version	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
4949311	27431466	G-MS	2	conceived and designed the analysis	conceived and designed the analysis	Conceived and designed the experiments	Conceptualization	YES
4949311	27431466	KM	2	programmed the survey instrument, managed data collection, and prepared some multi-item scales	programmed the survey instrument, managed data collection, and prepared some multi-item scales	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Investigation|Software	YES
4949311	27431466	SA	2	conceived and designed the analysis	conceived and designed the analysis	Conceived and designed the experiments	Conceptualization	YES
5536386	28794869	Hajar Ziaei Hezarjaribi	1	Data interpretation	Data interpretation	Analyzed the data	Formal analysis	YES
5536386	28794869	Mahdi Fakhar	1	Study concept|Data interpretation|Writing the paper	Study concept	Conceived and designed the experiments	Conceptualization	YES
5536386	28794869	Mahdi Fakhar	1	Study concept|Data interpretation|Writing the paper	Data interpretation	Analyzed the data	Formal analysis	YES
5536386	28794869	Mahdi Fakhar	1	Study concept|Data interpretation|Writing the paper	Writing the paper	Wrote the paper	Writing - Original Draft	YES
5536386	28794869	Masoud Soosaraei	1	Data collection|Data interpretation|Writing the paper	Data collection	Performed the experiments	Investigation	YES
5536386	28794869	Masoud Soosaraei	1	Data collection|Data interpretation|Writing the paper	Data interpretation	Analyzed the data	Formal analysis	YES
5536386	28794869	Masoud Soosaraei	1	Data collection|Data interpretation|Writing the paper	Writing the paper	Wrote the paper	Writing - Original Draft	YES
5536386	28794869	Saeed HosseiniTeshnizi	1	Data interpretation	Data interpretation	Analyzed the data	Formal analysis	YES
5552723	28848585	KD	2	carried out the experiments and analyzed the results	carried out the experiments and analyzed the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5552723	28848585	TP	2	carried out the experiments and analyzed the results	carried out the experiments and analyzed the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5552723	28848585	YG	2	provided scientific advice and revised the manuscript	provided scientific advice and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5552723	28848585	YJ	2	carried out the experiments and analyzed the results|wrote the manuscript	carried out the experiments and analyzed the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5552723	28848585	YJ	2	carried out the experiments and analyzed the results|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5552723	28848585	ZB	2	carried out the experiments and analyzed the results	carried out the experiments and analyzed the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5552723	28848585	ZL	2	designed the research and led this project	designed the research and led this project	Conceived and designed the experiments	Methodology	YES
4949312	27431473	JK	2	advised on content and provided writing and editorial input and guidance	advised on content and provided writing and editorial input and guidance	Wrote the paper	Supervision|Writing - Review & Editing	YES
4949312	27431473	MS	2	provided writing and editorial input, as well as other support	provided writing and editorial input, as well as other support	Wrote the paper	Writing - Review & Editing	YES
4949312	27431473	VD	2	provided key ideas for content and led the writing for the manuscript	provided key ideas for content and led the writing for the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5310272	28198668	JY	2	designed the study|performed the data analysis|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5310272	28198668	JY	2	designed the study|performed the data analysis|wrote the manuscript	performed the data analysis	Analyzed the data	Formal analysis	YES
5310272	28198668	JY	2	designed the study|performed the data analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5310272	28198668	SY	2	designed the study|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5310272	28198668	SY	2	designed the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6163858	30142902	All authors	2	have significantly contributed to this review	have significantly contributed to this review	-	-	NO
6163858	30142902	All of the authors	2	analyzed the articles and endorsed the inclusion of relevant studies	analyzed the articles and endorsed the inclusion of relevant studies	Analyzed the data	Formal analysis	YES
6163858	30142902	All the authors	2	contributed to the final draft and the checking and reviewing of the manuscript	contributed to the final draft and the checking and reviewing of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6163858	30142902	F.P.	2	conducted the initial search, identification, screening, and tabulation, analyzed the articles, and completed the first draft	conducted the initial search, identification, screening, and tabulation, analyzed the articles, and completed the first draft	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6163858	30142902	S.J.	2	searched and provided related articles, provided the framework for writing the review, and strengthened the whole review until the final phase	searched and provided related articles, provided the framework for writing the review, and strengthened the whole review until the final phase	Wrote the paper	Writing - Review & Editing	YES
4405610	25898016	HJ	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4405610	25898016	HJ	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405610	25898016	MHM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405610	25898016	MHM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405610	25898016	MHM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405610	25898016	MHM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405610	25898016	MUA	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405610	25898016	MUA	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405610	25898016	SAK	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4405610	25898016	SAK	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4405610	25898016	SGK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405610	25898016	SGK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405610	25898016	SGK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405610	25898016	SGK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405610	25898016	SGK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4491381	26180818	All authors	2	contributed to concept and design of the study, input to the development of the automatic segmentation algorithm, and revised the paper|read and approved the final paper	contributed to concept and design of the study, input to the development of the automatic segmentation algorithm, and revised the paper	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Methodology|Software|Writing - Original Draft|Writing - Review & Editing	YES
4491381	26180818	All authors	2	contributed to concept and design of the study, input to the development of the automatic segmentation algorithm, and revised the paper|read and approved the final paper	read and approved the final paper	-	-	NO
4491381	26180818	Einar Heiberg	2	conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4491381	26180818	Erik Hedstrom	2	performed manual delineation in training set and test set	performed manual delineation in training set and test set	Performed the experiments	Investigation	YES
4491381	26180818	Hakan Arheden	2	performed consensus reading of the manual delineation in training set	performed consensus reading of the manual delineation in training set	Performed the experiments	Investigation	YES
4491381	26180818	Jane Tufvesson	2	developed and implemented the automatic segmentation algorithm, analyzed and interpreted segmentation results, and drafted the paper	developed and implemented the automatic segmentation algorithm, analyzed and interpreted segmentation results, and drafted the paper	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Software|Writing - Original Draft	YES
4491381	26180818	Katarina Steding-Ehrenborg	2	included normal subjects and athletes to the study	included normal subjects and athletes to the study	-	-	NO
4491381	26180818	Marcus Carlsson	2	performed second observer manual delineation	performed second observer manual delineation	Performed the experiments	Investigation	YES
5552756	28848589	All authors	2	approved the manuscript	approved the manuscript	-	-	NO
5552756	28848589	NA	2	critically evaluated the manuscript	critically evaluated the manuscript	-	-	NO
5552756	28848589	PM	2	critically evaluated the manuscript	critically evaluated the manuscript	-	-	NO
5552756	28848589	VP	2	collected literature and wrote the manuscript	collected literature and wrote the manuscript	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5552756	28848589	WA	2	collected literature and wrote the manuscript	collected literature and wrote the manuscript	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3246294	22216407	Both authors	2	contributed significantly in study conception and design, acquisition, analysis, and interpretation of data as well as paper preparation	contributed significantly in study conception and design, acquisition, analysis, and interpretation of data as well as paper preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Methodology|Resources	YES
5537372	28794867	Heiko Baumann	7	data collection, data analysis, writing	data collection, data analysis, writing	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation	YES
5537372	28794867	Jurgen Biscoping	7	data analysis, writing	data analysis, writing	Analyzed the data|Wrote the paper	Formal analysis	YES
5537372	28794867	Michael Henrich	7	data collection, data analysis, writing	data collection, data analysis, writing	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation	YES
5537372	28794867	Phillip Fichtenkamm	7	data collection, data analysis	data collection, data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5537372	28794867	Thomas Schneider	7	data collection, data analysis	data collection, data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5537375	28794866	A. Greig	7	study design, reviewed the writing and approval of the final manuscript for submission	study design, reviewed the writing and approval of the final manuscript for submission	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5537375	28794866	R. A. Agha	7	study design, data analysis, writing and approval of the final manuscript for submission	study design, data analysis, writing and approval of the final manuscript for submission	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5537375	28794866	W. W. Keijzer	7	data collection, writing and approval of the final manuscript for submission	data collection, writing and approval of the final manuscript for submission	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
4949313	27431474	AA	2	edited and provided critical input to the manuscript	edited and provided critical input to the manuscript	Wrote the paper	Writing - Review & Editing	YES
4949313	27431474	All authors	2	reviewed and approved the final manuscript	reviewed and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4949313	27431474	GM	2	drafted and revised the manuscript	drafted and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4949313	27431474	JR	2	were involved in designing the study and programme|edited and provided critical input to the manuscript	were involved in designing the study and programme	Conceived and designed the experiments	Methodology	YES
4949313	27431474	JR	2	were involved in designing the study and programme|edited and provided critical input to the manuscript	edited and provided critical input to the manuscript	Wrote the paper	Writing - Review & Editing	YES
4949313	27431474	NM	2	analyzed and interpreted the data	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
4949313	27431474	SM	2	were involved in designing the study and programme|edited and provided critical input to the manuscript	were involved in designing the study and programme	Conceived and designed the experiments	Methodology	YES
4949313	27431474	SM	2	were involved in designing the study and programme|edited and provided critical input to the manuscript	edited and provided critical input to the manuscript	Wrote the paper	Writing - Review & Editing	YES
4949313	27431474	SS	2	were involved in designing the study and programme|drafted and revised the manuscript	were involved in designing the study and programme	Conceived and designed the experiments	Methodology	YES
4949313	27431474	SS	2	were involved in designing the study and programme|drafted and revised the manuscript	drafted and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4949313	27431474	VA	2	analyzed and interpreted the data	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
4405814	25875204	CFV	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405814	25875204	MBH	PLoS5	Analyzed the data|Wrote the paper|Drafted the manuscript|Searched for studies, extracted and compiled data in tabular form|Selected studies for network perspective of comorbidities and wrote respective parts|Filled in quality criteria list	Analyzed the data	Analyzed the data	Formal analysis	YES
4405814	25875204	MBH	PLoS5	Analyzed the data|Wrote the paper|Drafted the manuscript|Searched for studies, extracted and compiled data in tabular form|Selected studies for network perspective of comorbidities and wrote respective parts|Filled in quality criteria list	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405814	25875204	MBH	PLoS5	Analyzed the data|Wrote the paper|Drafted the manuscript|Searched for studies, extracted and compiled data in tabular form|Selected studies for network perspective of comorbidities and wrote respective parts|Filled in quality criteria list	Drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4405814	25875204	MBH	PLoS5	Analyzed the data|Wrote the paper|Drafted the manuscript|Searched for studies, extracted and compiled data in tabular form|Selected studies for network perspective of comorbidities and wrote respective parts|Filled in quality criteria list	Searched for studies, extracted and compiled data in tabular form	Performed the experiments	Data curation|Investigation	YES
4405814	25875204	MBH	PLoS5	Analyzed the data|Wrote the paper|Drafted the manuscript|Searched for studies, extracted and compiled data in tabular form|Selected studies for network perspective of comorbidities and wrote respective parts|Filled in quality criteria list	Selected studies for network perspective of comorbidities and wrote respective parts	Wrote the paper	Writing - Original Draft	YES
4405814	25875204	MBH	PLoS5	Analyzed the data|Wrote the paper|Drafted the manuscript|Searched for studies, extracted and compiled data in tabular form|Selected studies for network perspective of comorbidities and wrote respective parts|Filled in quality criteria list	Filled in quality criteria list	-	-	NO
4405814	25875204	MEW	PLoS5	Analyzed the data|Wrote the paper|Filled in quality criteria list	Analyzed the data	Analyzed the data	Formal analysis	YES
4405814	25875204	MEW	PLoS5	Analyzed the data|Wrote the paper|Filled in quality criteria list	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405814	25875204	MEW	PLoS5	Analyzed the data|Wrote the paper|Filled in quality criteria list	Filled in quality criteria list	-	-	NO
4405814	25875204	RL	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6163905	30002273	D.W.-S.	PLoS52	conceived and designed the study|developed the survey and collected the data|wrote the paper	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6163905	30002273	D.W.-S.	PLoS52	conceived and designed the study|developed the survey and collected the data|wrote the paper	developed the survey and collected the data	Performed the experiments	Investigation	YES
6163905	30002273	D.W.-S.	PLoS52	conceived and designed the study|developed the survey and collected the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6163905	30002273	E.H.	PLoS52	conceived and designed the study|developed the survey and collected the data|wrote the paper	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6163905	30002273	E.H.	PLoS52	conceived and designed the study|developed the survey and collected the data|wrote the paper	developed the survey and collected the data	Performed the experiments	Investigation	YES
6163905	30002273	E.H.	PLoS52	conceived and designed the study|developed the survey and collected the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6163905	30002273	M.B.	PLoS52	conceived and designed the study|developed the survey and collected the data|analyzed the data|wrote the paper	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6163905	30002273	M.B.	PLoS52	conceived and designed the study|developed the survey and collected the data|analyzed the data|wrote the paper	developed the survey and collected the data	Performed the experiments	Investigation	YES
6163905	30002273	M.B.	PLoS52	conceived and designed the study|developed the survey and collected the data|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
6163905	30002273	M.B.	PLoS52	conceived and designed the study|developed the survey and collected the data|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6163905	30002273	Y.Y.	PLoS52	conceived and designed the study|analyzed the data|wrote the paper	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6163905	30002273	Y.Y.	PLoS52	conceived and designed the study|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
6163905	30002273	Y.Y.	PLoS52	conceived and designed the study|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5310273	28198673	CHC	2	lead the clinical study and sample collection	lead the clinical study and sample collection	Performed the experiments	Investigation	YES
5310273	28198673	CL	2	designed the study|analyzed and interpreted the data	designed the study	Conceived and designed the experiments	Methodology	YES
5310273	28198673	CL	2	designed the study|analyzed and interpreted the data	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5310273	28198673	CMC	2	processed the samples and generated the sequence data	processed the samples and generated the sequence data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5310273	28198673	CTW	2	lead the clinical study and sample collection	lead the clinical study and sample collection	Performed the experiments	Investigation	YES
5310273	28198673	HCT	2	designed the study|lead the clinical study and sample collection	designed the study	Conceived and designed the experiments	Methodology	YES
5310273	28198673	HCT	2	designed the study|lead the clinical study and sample collection	lead the clinical study and sample collection	Performed the experiments	Investigation	YES
5310273	28198673	HDH	2	designed the study|analyzed and interpreted the data|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5310273	28198673	HDH	2	designed the study|analyzed and interpreted the data|wrote the manuscript	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5310273	28198673	HDH	2	designed the study|analyzed and interpreted the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5310273	28198673	HMC	2	analyzed and interpreted the data|wrote the manuscript	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5310273	28198673	HMC	2	analyzed and interpreted the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5310273	28198673	HMW	2	processed the samples and generated the sequence data	processed the samples and generated the sequence data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5310273	28198673	JYC	2	processed the samples and generated the sequence data	processed the samples and generated the sequence data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5310273	28198673	KYL	2	lead the clinical study and sample collection	lead the clinical study and sample collection	Performed the experiments	Investigation	YES
5310273	28198673	SLW	2	lead the clinical study and sample collection	lead the clinical study and sample collection	Performed the experiments	Investigation	YES
5310273	28198673	THC	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5310273	28198673	WCW	2	processed the samples and generated the sequence data|analyzed and interpreted the data|wrote the manuscript	processed the samples and generated the sequence data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5310273	28198673	WCW	2	processed the samples and generated the sequence data|analyzed and interpreted the data|wrote the manuscript	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5310273	28198673	WCW	2	processed the samples and generated the sequence data|analyzed and interpreted the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5552757	28848590	All authors	PLoS52	edited and reviewed the manuscript	edited and reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5552757	28848590	FW	PLoS52	provided helpful suggestions for the data analysis and during the manuscript preparation	provided helpful suggestions for the data analysis and during the manuscript preparation	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
5552757	28848590	GY	PLoS52	provided helpful suggestions for the data analysis and during the manuscript preparation	provided helpful suggestions for the data analysis and during the manuscript preparation	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
5552757	28848590	JW	PLoS52	designed the research|wrote the paper	designed the research	Conceived and designed the experiments	Methodology	YES
5552757	28848590	JW	PLoS52	designed the research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5552757	28848590	NZ	PLoS52	designed the research|performed the experimental work and the data analysis|wrote the paper	designed the research	Conceived and designed the experiments	Methodology	YES
5552757	28848590	NZ	PLoS52	designed the research|performed the experimental work and the data analysis|wrote the paper	performed the experimental work and the data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5552757	28848590	NZ	PLoS52	designed the research|performed the experimental work and the data analysis|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5552757	28848590	SB	PLoS52	performed the experimental work and the data analysis	performed the experimental work and the data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5552757	28848590	WG	PLoS52	provided helpful suggestions for the data analysis and during the manuscript preparation	provided helpful suggestions for the data analysis and during the manuscript preparation	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
5552757	28848590	WL	PLoS52	performed the experimental work and the data analysis	performed the experimental work and the data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5552757	28848590	WTL	PLoS52	provided helpful suggestions for the data analysis and during the manuscript preparation	provided helpful suggestions for the data analysis and during the manuscript preparation	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
5310274	28198674	RY	PLoS52	directed the research project|accumulated and organized the source data	directed the research project	-	Supervision	YES
5310274	28198674	RY	PLoS52	directed the research project|accumulated and organized the source data	accumulated and organized the source data	-	-	NO
5310274	28198674	SI	PLoS52	directed the research project	directed the research project	-	Supervision	YES
5310274	28198674	SM	PLoS52	directed the research project	directed the research project	-	Supervision	YES
5310274	28198674	YZ	PLoS52	conceived the study|performed the experiments|drafted different sections of the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5310274	28198674	YZ	PLoS52	conceived the study|performed the experiments|drafted different sections of the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5310274	28198674	YZ	PLoS52	conceived the study|performed the experiments|drafted different sections of the manuscript	drafted different sections of the manuscript	Wrote the paper	Writing - Original Draft	YES
4405815	25860019	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405815	25860019	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405815	25860019	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405815	25860019	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405815	25860019	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405815	25860019	KH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405815	25860019	KH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405815	25860019	KH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405815	25860019	KH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405815	25860019	KH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405815	25860019	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405815	25860019	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4405815	25860019	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405815	25860019	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405815	25860019	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4405815	25860019	TN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4405815	25860019	TN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4405815	25860019	TN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4405815	25860019	TN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3286886	22400106	All authors	2	contributed to subsequent drafts and reviewed and approved the final manuscript	contributed to subsequent drafts and reviewed and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3286886	22400106	C. Kityo	2	established the march cohort and supervised data collection|conceived the substudy|critically reviewed the paper	established the march cohort and supervised data collection	Performed the experiments	Investigation|Supervision	YES
3286886	22400106	C. Kityo	2	established the march cohort and supervised data collection|conceived the substudy|critically reviewed the paper	conceived the substudy	Conceived and designed the experiments	Conceptualization	YES
3286886	22400106	C. Kityo	2	established the march cohort and supervised data collection|conceived the substudy|critically reviewed the paper	critically reviewed the paper	Wrote the paper	Writing - Review & Editing	YES
3286886	22400106	J. Calis	2	conceived the substudy|critically reviewed the paper	conceived the substudy	Conceived and designed the experiments	Conceptualization	YES
3286886	22400106	J. Calis	2	conceived the substudy|critically reviewed the paper	critically reviewed the paper	Wrote the paper	Writing - Review & Editing	YES
3286886	22400106	J. Kayiwa	2	contributed to implementation	contributed to implementation	Performed the experiments	Investigation	YES
3286886	22400106	K. C. E. Sigaloff	2	contributed to implementation|conceived the substudy|assisted with the analyzed the data and wrote the first draft of the manuscript with	contributed to implementation	Performed the experiments	Investigation	YES
3286886	22400106	K. C. E. Sigaloff	2	contributed to implementation|conceived the substudy|assisted with the analyzed the data and wrote the first draft of the manuscript with	conceived the substudy	Conceived and designed the experiments	Conceptualization	YES
3286886	22400106	K. C. E. Sigaloff	2	contributed to implementation|conceived the substudy|assisted with the analyzed the data and wrote the first draft of the manuscript with	assisted with the analyzed the data and wrote the first draft of the manuscript with	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3286886	22400106	P. Mugyenyi	2	established the march cohort and supervised data collection	established the march cohort and supervised data collection	Performed the experiments	Investigation|Supervision	YES
3286886	22400106	R. L. Hamers	2	assisted with the analyzed the data and wrote the first draft of the manuscript with	assisted with the analyzed the data and wrote the first draft of the manuscript with	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3286886	22400106	S. P. Geelen	2	conceived the substudy|critically reviewed the paper	conceived the substudy	Conceived and designed the experiments	Conceptualization	YES
3286886	22400106	S. P. Geelen	2	conceived the substudy|critically reviewed the paper	critically reviewed the paper	Wrote the paper	Writing - Review & Editing	YES
3286886	22400106	T. F. R. Wit	2	conceived the substudy|critically reviewed the paper	conceived the substudy	Conceived and designed the experiments	Conceptualization	YES
3286886	22400106	T. F. R. Wit	2	conceived the substudy|critically reviewed the paper	critically reviewed the paper	Wrote the paper	Writing - Review & Editing	YES
3286886	22400106	T. S. Boender	2	conceived the substudy|analyzed the data and wrote the first draft of the manuscript with	conceived the substudy	Conceived and designed the experiments	Conceptualization	YES
3286886	22400106	T. S. Boender	2	conceived the substudy|analyzed the data and wrote the first draft of the manuscript with	analyzed the data and wrote the first draft of the manuscript with	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3286886	22400106	V. Musiime	2	established the march cohort and supervised data collection|critically reviewed the paper	established the march cohort and supervised data collection	Performed the experiments	Investigation|Supervision	YES
3286886	22400106	V. Musiime	2	established the march cohort and supervised data collection|critically reviewed the paper	critically reviewed the paper	Wrote the paper	Writing - Review & Editing	YES
4949314	27431468	GW	2	contributed to study design and implementation, data analysis and interpretation, and writing of the manuscript	contributed to study design and implementation, data analysis and interpretation, and writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
4949314	27431468	JM	2	contributed to data analysis and interpretation, and writing of the manuscript	contributed to data analysis and interpretation, and writing of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4949314	27431468	RK	2	contributed to study design and implementation, data analysis and interpretation, and writing of the manuscript	contributed to study design and implementation, data analysis and interpretation, and writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
5537425	28794870	CF	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5537425	28794870	GC	PLoS52	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5552816	28848579	All authors	2	contributed to the revision of the manuscript and approved the final manuscript	contributed to the revision of the manuscript and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5552816	28848579	JP	2	designed the experiments and contributed to the data interpretation|undertook the experiment and collected the data|analyzed the data and drafted the manuscript	designed the experiments and contributed to the data interpretation	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5552816	28848579	JP	2	designed the experiments and contributed to the data interpretation|undertook the experiment and collected the data|analyzed the data and drafted the manuscript	undertook the experiment and collected the data	Performed the experiments	Investigation	YES
5552816	28848579	JP	2	designed the experiments and contributed to the data interpretation|undertook the experiment and collected the data|analyzed the data and drafted the manuscript	analyzed the data and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5552816	28848579	KS	2	designed the experiments and contributed to the data interpretation	designed the experiments and contributed to the data interpretation	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5552816	28848579	NT	2	designed the experiments and contributed to the data interpretation	designed the experiments and contributed to the data interpretation	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5552816	28848579	TC	2	designed the experiments and contributed to the data interpretation	designed the experiments and contributed to the data interpretation	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5552816	28848579	YD	2	designed the experiments and contributed to the data interpretation|undertook the experiment and collected the data	designed the experiments and contributed to the data interpretation	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5552816	28848579	YD	2	designed the experiments and contributed to the data interpretation|undertook the experiment and collected the data	undertook the experiment and collected the data	Performed the experiments	Investigation	YES
6164148	30200266	C.U.	2	analyzed donepezil samples	analyzed donepezil samples	Analyzed the data	Formal analysis	YES
6164148	30200266	H.T.	2	planned the study design, analyzed the experimental data and contributed suggestions regarding the manuscript	planned the study design, analyzed the experimental data and contributed suggestions regarding the manuscript	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
6164148	30200266	J.E.	2	participated in experiments	participated in experiments	Performed the experiments	Investigation	YES
6164148	30200266	K.I.	2	analyzed donepezil samples	analyzed donepezil samples	Analyzed the data	Formal analysis	YES
6164148	30200266	K.K.	2	planned the study design, analyzed the experimental data and contributed suggestions regarding the manuscript|coordinated the study	planned the study design, analyzed the experimental data and contributed suggestions regarding the manuscript	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
6164148	30200266	K.K.	2	planned the study design, analyzed the experimental data and contributed suggestions regarding the manuscript|coordinated the study	coordinated the study	-	Project administration	YES
6164148	30200266	M.R.I.	2	performed the experiments, participated in study design and prepared the manuscript	performed the experiments, participated in study design and prepared the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
6164148	30200266	M.S.R.	2	participated in experiments	participated in experiments	Performed the experiments	Investigation	YES
6164148	30200266	N.Y.	2	planned the study design, analyzed the experimental data and contributed suggestions regarding the manuscript|coordinated the study	planned the study design, analyzed the experimental data and contributed suggestions regarding the manuscript	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
6164148	30200266	N.Y.	2	planned the study design, analyzed the experimental data and contributed suggestions regarding the manuscript|coordinated the study	coordinated the study	-	Project administration	YES
6164148	30200266	S.K.	2	participated in experiments	participated in experiments	Performed the experiments	Investigation	YES
6164148	30200266	T.T.	2	analyzed donepezil samples	analyzed donepezil samples	Analyzed the data	Formal analysis	YES
6164148	30200266	T.Z.	2	planned the study design, analyzed the experimental data and contributed suggestions regarding the manuscript	planned the study design, analyzed the experimental data and contributed suggestions regarding the manuscript	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
5540698	28794874	Edoardo Raposio	7	study concept	study concept	Conceived and designed the experiments	Conceptualization	YES
5540698	28794874	Francesco Simonacci	7	photos	photos	-	-	NO
5540698	28794874	Marco Gardani	7	writing the paper	writing the paper	Wrote the paper	Writing - Original Draft	YES
5540698	28794874	Mariangela Pesce	7	photos	photos	-	-	NO
5540698	28794874	Michele Pio Greco	7	study concept	study concept	Conceived and designed the experiments	Conceptualization	YES
5540698	28794874	Nicolo Bertozzi	7	revised the paper	revised the paper	Wrote the paper	Writing - Review & Editing	YES
5540698	28794874	Pierluigi Santi	7	photos	photos	-	-	NO
5310275	28198677	LC	2	performed the realtime pcr analysis and participated in data analysis	performed the realtime pcr analysis and participated in data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5310275	28198677	LL	2	directed the research project and edited the manuscript	directed the research project and edited the manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
5310275	28198677	PX	2	designed the study and composed the manuscript	designed the study and composed the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5310275	28198677	XJ	2	performed the realtime pcr analysis and participated in data analysis	performed the realtime pcr analysis and participated in data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5310275	28198677	XL	2	directed the research project and edited the manuscript	directed the research project and edited the manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
5310275	28198677	YK	2	performed the data collection and analysis	performed the data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4406103	25849083	LK	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406103	25849083	LK	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406103	25849083	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406103	25849083	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406103	25849083	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406103	25849083	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406103	25849083	MM	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406103	25849083	MM	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406103	25849083	MN	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406103	25849083	MN	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406103	25849083	MN	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406103	25849083	PDNH	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406103	25849083	PDNH	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4949315	27431469	ANC	2	contributed to developing the discussion section and tailoring the manuscript to the format required	contributed to developing the discussion section and tailoring the manuscript to the format required	Wrote the paper	Writing - Original Draft	YES
4949315	27431469	All authors	2	have read and approved the final manuscript	have read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4949315	27431469	CB	2	provided comments to earlier drafts of the document	provided comments to earlier drafts of the document	Wrote the paper	Writing - Original Draft	YES
4949315	27431469	JV	2	collaborated giving ideas, suggestions and recommendations according to her experience as member of the transwomen community	collaborated giving ideas, suggestions and recommendations according to her experience as member of the transwomen community	Conceived and designed the experiments	Conceptualization	YES
4949315	27431469	PC	2	provided comments to earlier drafts of the document	provided comments to earlier drafts of the document	Wrote the paper	Writing - Original Draft	YES
4949315	27431469	RC	2	provided comments to earlier drafts of the document	provided comments to earlier drafts of the document	Wrote the paper	Writing - Original Draft	YES
4949315	27431469	XS	2	conceived the main ideas of the paper and was in charge of the manuscript writing|on several iterations, suggested references and completed the main ideas	conceived the main ideas of the paper and was in charge of the manuscript writing	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4949315	27431469	XS	2	conceived the main ideas of the paper and was in charge of the manuscript writing|on several iterations, suggested references and completed the main ideas	on several iterations, suggested references and completed the main ideas	Conceived and designed the experiments	Conceptualization	YES
6164184	30071649	Each author	2	contributed to study design, data collection, and data analysis	contributed to study design, data collection, and data analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Methodology|Resources	YES
5554343	28848599	BL	2	designed the experiments and contributed to the date analysis	designed the experiments and contributed to the date analysis	Conceived and designed the experiments	Methodology	YES
5554343	28848599	JL	2	provided technical assistance	provided technical assistance	Performed the experiments	Investigation	YES
5554343	28848599	LW	2	provided technical assistance	provided technical assistance	Performed the experiments	Investigation	YES
5554343	28848599	MJ	2	performed most of the experiments	performed most of the experiments	Performed the experiments	Investigation	YES
5554343	28848599	ND	2	contributed to some of the experiments	contributed to some of the experiments	Performed the experiments	Investigation	YES
5554343	28848599	PD	2	performed most of the experiments	performed most of the experiments	Performed the experiments	Investigation	YES
5554343	28848599	QZ	2	contributed to some of the experiments	contributed to some of the experiments	Performed the experiments	Investigation	YES
5554343	28848599	SX	2	contributed to some of the experiments	contributed to some of the experiments	Performed the experiments	Investigation	YES
5554343	28848599	WJ	2	conceived the project, supervised the experiments, and complemented the writing	conceived the project, supervised the experiments, and complemented the writing	Conceived and designed the experiments|Wrote the paper	Conceptualization|Supervision	YES
5554343	28848599	WM	2	provided technical assistance	provided technical assistance	Performed the experiments	Investigation	YES
5554343	28848599	YZ	2	provided technical assistance	provided technical assistance	Performed the experiments	Investigation	YES
4949316	27431471	JHL	2	participated in conceptualizing the study, designing the protocol and questionnaires, and managing the data collection	participated in conceptualizing the study, designing the protocol and questionnaires, and managing the data collection	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
4949316	27431471	JTFL	2	participated in conceptualizing the study, designing the protocol and questionnaires, providing scientific and management leadership, interpreting the data, and drafting and revising the manuscript critically	participated in conceptualizing the study, designing the protocol and questionnaires, providing scientific and management leadership, interpreting the data, and drafting and revising the manuscript critically	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Data curation|Formal analysis|Methodology|Resources|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
4949316	27431471	TM	2	participated in conceptualizing the study, commented on the questionnaire and coordinated the data collection	participated in conceptualizing the study, commented on the questionnaire and coordinated the data collection	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Project administration	YES
4949316	27431471	YC	2	participated in conceptualizing the study, designing the protocol and questionnaires, managing the data collection and revising the manuscript critically	participated in conceptualizing the study, designing the protocol and questionnaires, managing the data collection and revising the manuscript critically	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Writing - Review & Editing	YES
4949316	27431471	YL	2	participated in conceptualizing the study, commented on the questionnaire and coordinated the data collection	participated in conceptualizing the study, commented on the questionnaire and coordinated the data collection	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Project administration	YES
4949316	27431471	ZW	2	participated in designing the questionnaires, analyzing and interpreting the data, reviewing the literature and drafting and revising the manuscript	participated in designing the questionnaires, analyzing and interpreting the data, reviewing the literature and drafting and revising the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
4406440	25901351	DRM	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406440	25901351	DRM	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406440	25901351	DSM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406440	25901351	DSM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406440	25901351	DSM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406440	25901351	LAB	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406440	25901351	LAB	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5554346	28848594	AA	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5554346	28848594	BS	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5554346	28848594	SB	PLoS52	conceived the research plans	conceived the research plans	Conceived and designed the experiments	Conceptualization	YES
5554346	28848594	SM-B	PLoS52	conceived the research plans	conceived the research plans	Conceived and designed the experiments	Conceptualization	YES
6164212	30200444	I.D.M.	CRediT	Software|Writing--original draft preparation|Writing--review & editing	Software	Contributed reagents/materials/analysis tools	Software	YES
6164212	30200444	I.D.M.	CRediT	Software|Writing--original draft preparation|Writing--review & editing	Writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6164212	30200444	I.D.M.	CRediT	Software|Writing--original draft preparation|Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6164212	30200444	I.M.	CRediT	Software|Investigation	Software	Contributed reagents/materials/analysis tools	Software	YES
6164212	30200444	I.M.	CRediT	Software|Investigation	Investigation	Performed the experiments	Investigation	YES
6164212	30200444	L.P.	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
6164212	30200444	M.I.	CRediT	Conceptualization|Methodology|Software|Writing--original draft preparation|Writing--review & editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6164212	30200444	M.I.	CRediT	Conceptualization|Methodology|Software|Writing--original draft preparation|Writing--review & editing	Methodology	Performed the experiments	Methodology	YES
6164212	30200444	M.I.	CRediT	Conceptualization|Methodology|Software|Writing--original draft preparation|Writing--review & editing	Software	Contributed reagents/materials/analysis tools	Software	YES
6164212	30200444	M.I.	CRediT	Conceptualization|Methodology|Software|Writing--original draft preparation|Writing--review & editing	Writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6164212	30200444	M.I.	CRediT	Conceptualization|Methodology|Software|Writing--original draft preparation|Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
5310276	28198670	CS	2	provided the oral metagenomics data	provided the oral metagenomics data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5310276	28198670	CZ	2	provided the oral metagenomics data	provided the oral metagenomics data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5310276	28198670	FS	2	provided the oral metagenomics data	provided the oral metagenomics data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5310276	28198670	FY	2	provided the oral metagenomics data	provided the oral metagenomics data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5310276	28198670	GC	2	provided insights on software development	provided insights on software development	Contributed reagents/materials/analysis tools	Software	YES
5310276	28198670	JY	2	wrote the programming code for the software and built the website|provided the oral metagenomics data|tested the data|draft the manuscript	wrote the programming code for the software and built the website	Contributed reagents/materials/analysis tools|Wrote the paper	Software|Writing - Original Draft	YES
5310276	28198670	JY	2	wrote the programming code for the software and built the website|provided the oral metagenomics data|tested the data|draft the manuscript	provided the oral metagenomics data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5310276	28198670	JY	2	wrote the programming code for the software and built the website|provided the oral metagenomics data|tested the data|draft the manuscript	tested the data	Performed the experiments	Investigation	YES
5310276	28198670	JY	2	wrote the programming code for the software and built the website|provided the oral metagenomics data|tested the data|draft the manuscript	draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5310276	28198670	NK	2	provided the oral metagenomics data	provided the oral metagenomics data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5310276	28198670	QL	2	designed the research|draft the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
5310276	28198670	QL	2	designed the research|draft the manuscript	draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5310276	28198670	TQ	2	wrote the programming code for the software and built the website	wrote the programming code for the software and built the website	Contributed reagents/materials/analysis tools|Wrote the paper	Software|Writing - Original Draft	YES
5310276	28198670	YH	2	provided the oral metagenomics data	provided the oral metagenomics data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5310276	28198670	YZ	2	provided the oral metagenomics data	provided the oral metagenomics data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5540706	28794873	Hussain Shallwani	7	Conceived the idea, literature search and Write up. 3	Conceived the idea, literature search and Write up. 3	Conceived and designed the experiments|Wrote the paper	Conceptualization|Formal analysis	YES
5540706	28794873	Muhammad Ehsan Bari	7	Conceived the idea and finalised the draft	Conceived the idea and finalised the draft	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5540706	28794873	Muhammad Waqas	7	Review and Manuscript Modification. 4	Review and Manuscript Modification. 4	Wrote the paper	Writing - Review & Editing	YES
5540706	28794873	Sohaib Tariq	7	Formulated the methodology, literature search and Write up. 2	Formulated the methodology, literature search and Write up. 2	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Formal analysis|Methodology	YES
4949317	27431467	EW	2	conceived and designed the analysis and contributed to the writing of the manuscript	conceived and designed the analysis and contributed to the writing of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4949317	27431467	HJ	2	conducted the analyses	conducted the analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4949317	27431467	SA	2	conceived and designed the analysis and contributed to the writing of the manuscript	conceived and designed the analysis and contributed to the writing of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4949317	27431467	VL	2	conceived and designed the analysis and contributed to the writing of the manuscript	conceived and designed the analysis and contributed to the writing of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4949317	27431467	YHC	2	conducted the analyses	conducted the analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6164232	30081461	M.J.	CRediT	Conceptualization|methodology|writing-review and editing|visualization|supervision|project administration	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6164232	30081461	M.J.	CRediT	Conceptualization|methodology|writing-review and editing|visualization|supervision|project administration	methodology	Performed the experiments	Methodology	YES
6164232	30081461	M.J.	CRediT	Conceptualization|methodology|writing-review and editing|visualization|supervision|project administration	writing-review and editing	Wrote the paper	Writing - Review & Editing	YES
6164232	30081461	M.J.	CRediT	Conceptualization|methodology|writing-review and editing|visualization|supervision|project administration	visualization	Analyzed the data	Visualization	YES
6164232	30081461	M.J.	CRediT	Conceptualization|methodology|writing-review and editing|visualization|supervision|project administration	supervision	-	Supervision	YES
6164232	30081461	M.J.	CRediT	Conceptualization|methodology|writing-review and editing|visualization|supervision|project administration	project administration	-	Project administration	YES
6164232	30081461	S.M.A.	CRediT	Conceptualization|writing-review and editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6164232	30081461	S.M.A.	CRediT	Conceptualization|writing-review and editing	writing-review and editing	Wrote the paper	Writing - Review & Editing	YES
6164232	30081461	T.W.	CRediT	Conceptualization|methodology|validation|formal analysis|investigation|data curation|writing-original draft preparation|writing-review and editing|visualization|project administration	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6164232	30081461	T.W.	CRediT	Conceptualization|methodology|validation|formal analysis|investigation|data curation|writing-original draft preparation|writing-review and editing|visualization|project administration	methodology	Performed the experiments	Methodology	YES
6164232	30081461	T.W.	CRediT	Conceptualization|methodology|validation|formal analysis|investigation|data curation|writing-original draft preparation|writing-review and editing|visualization|project administration	validation	Performed the experiments	Validation	YES
6164232	30081461	T.W.	CRediT	Conceptualization|methodology|validation|formal analysis|investigation|data curation|writing-original draft preparation|writing-review and editing|visualization|project administration	formal analysis	Analyzed the data	Formal analysis	YES
6164232	30081461	T.W.	CRediT	Conceptualization|methodology|validation|formal analysis|investigation|data curation|writing-original draft preparation|writing-review and editing|visualization|project administration	investigation	Performed the experiments	Investigation	YES
6164232	30081461	T.W.	CRediT	Conceptualization|methodology|validation|formal analysis|investigation|data curation|writing-original draft preparation|writing-review and editing|visualization|project administration	data curation	Analyzed the data	Data curation	YES
6164232	30081461	T.W.	CRediT	Conceptualization|methodology|validation|formal analysis|investigation|data curation|writing-original draft preparation|writing-review and editing|visualization|project administration	writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
6164232	30081461	T.W.	CRediT	Conceptualization|methodology|validation|formal analysis|investigation|data curation|writing-original draft preparation|writing-review and editing|visualization|project administration	writing-review and editing	Wrote the paper	Writing - Review & Editing	YES
6164232	30081461	T.W.	CRediT	Conceptualization|methodology|validation|formal analysis|investigation|data curation|writing-original draft preparation|writing-review and editing|visualization|project administration	visualization	Analyzed the data	Visualization	YES
6164232	30081461	T.W.	CRediT	Conceptualization|methodology|validation|formal analysis|investigation|data curation|writing-original draft preparation|writing-review and editing|visualization|project administration	project administration	-	Project administration	YES
5544470	28808566	HG	2	supervised ro under the	supervised ro under the	-	Supervision	YES
5544470	28808566	HH	2	made, analyzed, and interpreted our patients imaging examinations|demonstrated surgery for our patients|supervised ro under the	made, analyzed, and interpreted our patients imaging examinations	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
5544470	28808566	HH	2	made, analyzed, and interpreted our patients imaging examinations|demonstrated surgery for our patients|supervised ro under the	demonstrated surgery for our patients	Performed the experiments	Investigation	YES
5544470	28808566	HH	2	made, analyzed, and interpreted our patients imaging examinations|demonstrated surgery for our patients|supervised ro under the	supervised ro under the	-	Supervision	YES
5544470	28808566	HM	2	supervised ro under the	supervised ro under the	-	Supervision	YES
5544470	28808566	KH	2	made, analyzed, and interpreted our patients imaging examinations|supervised ro under the	made, analyzed, and interpreted our patients imaging examinations	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
5544470	28808566	KH	2	made, analyzed, and interpreted our patients imaging examinations|supervised ro under the	supervised ro under the	-	Supervision	YES
5544470	28808566	NH	2	made, analyzed, and interpreted our patients imaging examinations|demonstrated surgery for our patients|supervised ro under the	made, analyzed, and interpreted our patients imaging examinations	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
5544470	28808566	NH	2	made, analyzed, and interpreted our patients imaging examinations|demonstrated surgery for our patients|supervised ro under the	demonstrated surgery for our patients	Performed the experiments	Investigation	YES
5544470	28808566	NH	2	made, analyzed, and interpreted our patients imaging examinations|demonstrated surgery for our patients|supervised ro under the	supervised ro under the	-	Supervision	YES
5544470	28808566	RO	2	made, analyzed, and interpreted our patients imaging examinations|under the	made, analyzed, and interpreted our patients imaging examinations	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
5544470	28808566	RO	2	made, analyzed, and interpreted our patients imaging examinations|under the	under the	-	-	NO
4406441	25901914	EM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406441	25901914	EM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406441	25901914	EM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406441	25901914	JLV	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406441	25901914	JLV	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406441	25901914	JMP	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406441	25901914	JMP	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406441	25901914	LM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406441	25901914	MV	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406441	25901914	MV	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406441	25901914	MV	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406441	25901914	NS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4406441	25901914	PM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406441	25901914	RR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406441	25901914	RR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406441	25901914	RR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406441	25901914	RR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406441	25901914	SB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406441	25901914	SB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406441	25901914	SB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406441	25901914	SD	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406441	25901914	SD	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5554363	28848576	FC	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5554363	28848576	FY	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5554363	28848576	HS	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5554363	28848576	JDi	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5554363	28848576	JDu	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5554363	28848576	JL	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5554363	28848576	KS	PLoS52	designed the research|analyzed the data and wrote the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
5554363	28848576	KS	PLoS52	designed the research|analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5554363	28848576	QW	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5554363	28848576	TY	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5554363	28848576	WL	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5554363	28848576	WY	PLoS52	analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5554363	28848576	WZ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5554363	28848576	XL	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5554363	28848576	XW	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5554363	28848576	YF	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5554363	28848576	YM	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5554363	28848576	YQ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
4949318	27431476	CS	2	summarized a subset of the articles|all contributed to the conclusions	summarized a subset of the articles	-	-	NO
4949318	27431476	CS	2	summarized a subset of the articles|all contributed to the conclusions	all contributed to the conclusions	-	-	NO
4949318	27431476	JK	2	summarized a subset of the articles|all contributed to the conclusions	summarized a subset of the articles	-	-	NO
4949318	27431476	JK	2	summarized a subset of the articles|all contributed to the conclusions	all contributed to the conclusions	-	-	NO
4949318	27431476	RW	2	conceptualized and outlined the paper|summarized a subset of the articles|all contributed to the conclusions	conceptualized and outlined the paper	Conceived and designed the experiments	Conceptualization	YES
4949318	27431476	RW	2	conceptualized and outlined the paper|summarized a subset of the articles|all contributed to the conclusions	summarized a subset of the articles	-	-	NO
4949318	27431476	RW	2	conceptualized and outlined the paper|summarized a subset of the articles|all contributed to the conclusions	all contributed to the conclusions	-	-	NO
4949318	27431476	TP	2	conceptualized and outlined the paper|all contributed to the conclusions	conceptualized and outlined the paper	Conceived and designed the experiments	Conceptualization	YES
4949318	27431476	TP	2	conceptualized and outlined the paper|all contributed to the conclusions	all contributed to the conclusions	-	-	NO
5310277	28198676	CZ	2	directed on experiments and data analysis	directed on experiments and data analysis	Analyzed the data	Formal analysis|Supervision	YES
5310277	28198676	LC	2	collected the samples, performed experiment and analyses	collected the samples, performed experiment and analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5310277	28198676	PH	2	directed on experiments and data analysis	directed on experiments and data analysis	Analyzed the data	Formal analysis|Supervision	YES
5310277	28198676	XJ	2	directed on experiments and data analysis	directed on experiments and data analysis	Analyzed the data	Formal analysis|Supervision	YES
5310277	28198676	XL	2	conceived study and revised manuscript	conceived study and revised manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5310277	28198676	YZ	2	performed analyses and drafted the manuscript	performed analyses and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6164373	30044389	A.H.	CRediT	Software|Formal analysis|Investigation|Writing-review & editing	Software	Contributed reagents/materials/analysis tools	Software	YES
6164373	30044389	A.H.	CRediT	Software|Formal analysis|Investigation|Writing-review & editing	Formal analysis	Analyzed the data	Formal analysis	YES
6164373	30044389	A.H.	CRediT	Software|Formal analysis|Investigation|Writing-review & editing	Investigation	Performed the experiments	Investigation	YES
6164373	30044389	A.H.	CRediT	Software|Formal analysis|Investigation|Writing-review & editing	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6164373	30044389	L.-A.H.	CRediT	Conceptualization|Methodology|Validation|Writing-original draft preparation|Supervision	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6164373	30044389	L.-A.H.	CRediT	Conceptualization|Methodology|Validation|Writing-original draft preparation|Supervision	Methodology	Performed the experiments	Methodology	YES
6164373	30044389	L.-A.H.	CRediT	Conceptualization|Methodology|Validation|Writing-original draft preparation|Supervision	Validation	Performed the experiments	Validation	YES
6164373	30044389	L.-A.H.	CRediT	Conceptualization|Methodology|Validation|Writing-original draft preparation|Supervision	Writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
6164373	30044389	L.-A.H.	CRediT	Conceptualization|Methodology|Validation|Writing-original draft preparation|Supervision	Supervision	-	Supervision	YES
6164373	30044389	L.H.	CRediT	Project administration	Project administration	-	Project administration	YES
6164373	30044389	M.H.	CRediT	Methodology|Validation|Formal analysis|Writing-review & editing|Visualization	Methodology	Performed the experiments	Methodology	YES
6164373	30044389	M.H.	CRediT	Methodology|Validation|Formal analysis|Writing-review & editing|Visualization	Validation	Performed the experiments	Validation	YES
6164373	30044389	M.H.	CRediT	Methodology|Validation|Formal analysis|Writing-review & editing|Visualization	Formal analysis	Analyzed the data	Formal analysis	YES
6164373	30044389	M.H.	CRediT	Methodology|Validation|Formal analysis|Writing-review & editing|Visualization	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6164373	30044389	M.H.	CRediT	Methodology|Validation|Formal analysis|Writing-review & editing|Visualization	Visualization	Analyzed the data	Visualization	YES
6164373	30044389	M.W.	CRediT	Conceptualization|Investigation|Resources|Data curation|Writing-original draft preparation|Visualization|Project administration	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6164373	30044389	M.W.	CRediT	Conceptualization|Investigation|Resources|Data curation|Writing-original draft preparation|Visualization|Project administration	Investigation	Performed the experiments	Investigation	YES
6164373	30044389	M.W.	CRediT	Conceptualization|Investigation|Resources|Data curation|Writing-original draft preparation|Visualization|Project administration	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6164373	30044389	M.W.	CRediT	Conceptualization|Investigation|Resources|Data curation|Writing-original draft preparation|Visualization|Project administration	Data curation	Analyzed the data	Data curation	YES
6164373	30044389	M.W.	CRediT	Conceptualization|Investigation|Resources|Data curation|Writing-original draft preparation|Visualization|Project administration	Writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
6164373	30044389	M.W.	CRediT	Conceptualization|Investigation|Resources|Data curation|Writing-original draft preparation|Visualization|Project administration	Visualization	Analyzed the data	Visualization	YES
6164373	30044389	M.W.	CRediT	Conceptualization|Investigation|Resources|Data curation|Writing-original draft preparation|Visualization|Project administration	Project administration	-	Project administration	YES
5560116	28861270	Ahmed Nabih El	7	Substantial contributions to the conception and design of the work and acquisition of data	Substantial contributions to the conception and design of the work and acquisition of data	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceptualization|Investigation|Resources	YES
5560116	28861270	Doaa Refaey Soliman	7	Drafting the work	Drafting the work	Wrote the paper	Writing - Original Draft	YES
4406442	25901362	DFW	PLoS5	Designed the figure	Designed the figure	Conceived and designed the experiments	Visualization	YES
4406442	25901362	HX	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4406442	25901362	HX	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4406442	25901362	JXQ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4406442	25901362	JXQ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4406442	25901362	JXQ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406442	25901362	QCZ	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406442	25901362	RXZ	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406442	25901362	RXZ	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406442	25901362	TYQ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the figure	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406442	25901362	TYQ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the figure	Performed the experiments	Performed the experiments	Investigation	YES
4406442	25901362	TYQ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the figure	Analyzed the data	Analyzed the data	Formal analysis	YES
4406442	25901362	TYQ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the figure	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406442	25901362	TYQ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the figure	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406442	25901362	TYQ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the figure	Designed the figure	Conceived and designed the experiments	Visualization	YES
4406442	25901362	YYY	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4406442	25901362	YYY	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4406442	25901362	YYY	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406442	25901362	ZWC	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5560118	28839932	All authors	2	contributed equally to all parts of the study as study design, data collections, data analysis and writing	contributed equally to all parts of the study as study design, data collections, data analysis and writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources	YES
4949319	27431472	AV	2	have all read and approved the final manuscript	have all read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4949319	27431472	CW	2	have all read and approved the final manuscript	have all read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4949319	27431472	DA	2	have all read and approved the final manuscript	have all read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4949319	27431472	ES	2	have all read and approved the final manuscript	have all read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4949319	27431472	FM	2	have all read and approved the final manuscript	have all read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4949319	27431472	JK	2	have all read and approved the final manuscript	have all read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4949319	27431472	JW	2	have all read and approved the final manuscript	have all read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4949319	27431472	MR	2	have all read and approved the final manuscript	have all read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4949319	27431472	RD	2	have all read and approved the final manuscript	have all read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4949319	27431472	TS	2	have all read and approved the final manuscript	have all read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4949319	27431472	The authors	2	have all contributed equally to the work	have all contributed equally to the work	-	-	NO
5554364	28848572	All authors	2	have read, revised, and approved the final manuscript	have read, revised, and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5554364	28848572	EVD	2	outlined and designed the study|conceived and supervised the experiments and critically revised the manuscript	outlined and designed the study	Conceived and designed the experiments	Methodology	YES
5554364	28848572	EVD	2	outlined and designed the study|conceived and supervised the experiments and critically revised the manuscript	conceived and supervised the experiments and critically revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Supervision|Writing - Review & Editing	YES
5554364	28848572	LD	2	outlined and designed the study|performed the experiments, analyzed and interpreted the data, and prepared the first draft of the manuscript	outlined and designed the study	Conceived and designed the experiments	Methodology	YES
5554364	28848572	LD	2	outlined and designed the study|performed the experiments, analyzed and interpreted the data, and prepared the first draft of the manuscript	performed the experiments, analyzed and interpreted the data, and prepared the first draft of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5554364	28848572	PR	2	conducted the molecular modeling	conducted the molecular modeling	Performed the experiments	Investigation|Methodology	YES
6164376	30103459	D.N.	CRediT	Methodology|Software|Formal analysis|Investigation|Visualization	Methodology	Performed the experiments	Methodology	YES
6164376	30103459	D.N.	CRediT	Methodology|Software|Formal analysis|Investigation|Visualization	Software	Contributed reagents/materials/analysis tools	Software	YES
6164376	30103459	D.N.	CRediT	Methodology|Software|Formal analysis|Investigation|Visualization	Formal analysis	Analyzed the data	Formal analysis	YES
6164376	30103459	D.N.	CRediT	Methodology|Software|Formal analysis|Investigation|Visualization	Investigation	Performed the experiments	Investigation	YES
6164376	30103459	D.N.	CRediT	Methodology|Software|Formal analysis|Investigation|Visualization	Visualization	Analyzed the data	Visualization	YES
6164376	30103459	M.A.K.	CRediT	Methodology	Methodology	Performed the experiments	Methodology	YES
4406443	25902290	NDG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Experiment design|Experiment execution|Analysis and write up	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406443	25902290	NDG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Experiment design|Experiment execution|Analysis and write up	Performed the experiments	Performed the experiments	Investigation	YES
4406443	25902290	NDG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Experiment design|Experiment execution|Analysis and write up	Analyzed the data	Analyzed the data	Formal analysis	YES
4406443	25902290	NDG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Experiment design|Experiment execution|Analysis and write up	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406443	25902290	NDG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Experiment design|Experiment execution|Analysis and write up	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406443	25902290	NDG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Experiment design|Experiment execution|Analysis and write up	Experiment design	Conceived and designed the experiments	Methodology	YES
4406443	25902290	NDG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Experiment design|Experiment execution|Analysis and write up	Experiment execution	Performed the experiments	Investigation	YES
4406443	25902290	NDG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Experiment design|Experiment execution|Analysis and write up	Analysis and write up	Wrote the paper	-	YES
4406443	25902290	RB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Experiment design|Experiment execution|Analysis and write up	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406443	25902290	RB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Experiment design|Experiment execution|Analysis and write up	Performed the experiments	Performed the experiments	Investigation	YES
4406443	25902290	RB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Experiment design|Experiment execution|Analysis and write up	Analyzed the data	Analyzed the data	Formal analysis	YES
4406443	25902290	RB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Experiment design|Experiment execution|Analysis and write up	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406443	25902290	RB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Experiment design|Experiment execution|Analysis and write up	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406443	25902290	RB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Experiment design|Experiment execution|Analysis and write up	Experiment design	Conceived and designed the experiments	Methodology	YES
4406443	25902290	RB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Experiment design|Experiment execution|Analysis and write up	Experiment execution	Performed the experiments	Investigation	YES
4406443	25902290	RB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Experiment design|Experiment execution|Analysis and write up	Analysis and write up	Wrote the paper	-	YES
5310278	28198666	ACT	2	conceived and supervised the overall study, design the analyses, and participated in drafting and editing of the manuscript	conceived and supervised the overall study, design the analyses, and participated in drafting and editing of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
5310278	28198666	All authors	2	have read, edited and approved the current version of the manuscript	have read, edited and approved the current version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5310278	28198666	BKBL	2	carried out data analysis and prepared the manuscript|carried out the experimental validation|designed, developed and implemented the design web interface	carried out data analysis and prepared the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5310278	28198666	BKBL	2	carried out data analysis and prepared the manuscript|carried out the experimental validation|designed, developed and implemented the design web interface	carried out the experimental validation	Performed the experiments	Investigation|Validation	YES
5310278	28198666	BKBL	2	carried out data analysis and prepared the manuscript|carried out the experimental validation|designed, developed and implemented the design web interface	designed, developed and implemented the design web interface	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5310278	28198666	CSL	2	designed, developed and implemented the design web interface	designed, developed and implemented the design web interface	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5310278	28198666	JKC	2	designed, developed and implemented the design web interface	designed, developed and implemented the design web interface	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5310278	28198666	KHT	2	carried out the experimental validation	carried out the experimental validation	Performed the experiments	Investigation|Validation	YES
5310278	28198666	SCC	2	conceived and supervised the overall study, design the analyses, and participated in drafting and editing of the manuscript	conceived and supervised the overall study, design the analyses, and participated in drafting and editing of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
5310278	28198666	TFK	2	conceived and supervised the overall study, design the analyses, and participated in drafting and editing of the manuscript	conceived and supervised the overall study, design the analyses, and participated in drafting and editing of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
5310278	28198666	ZAAR	2	conceived and supervised the overall study, design the analyses, and participated in drafting and editing of the manuscript	conceived and supervised the overall study, design the analyses, and participated in drafting and editing of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
5562045	28855982	B.R.	2	interpretation of data, review & revision of article and final approval for publication	interpretation of data, review & revision of article and final approval for publication	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5562045	28855982	C.Z.	2	data collection, data analysis, review & revision of article and final approval for publication	data collection, data analysis, review & revision of article and final approval for publication	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
5562045	28855982	J.P.	2	interpretation of data, review & revision of article and final approval for publication	interpretation of data, review & revision of article and final approval for publication	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5562045	28855982	W.R.	2	data collection, data analysis, review & revision of article and final approval for publication	data collection, data analysis, review & revision of article and final approval for publication	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
4951529	27435710	AM	2	provided additional detail and examples from their work	provided additional detail and examples from their work	-	-	NO
4951529	27435710	AS	2	developed the initial outline of the paper|provided additional detail and examples from their work	developed the initial outline of the paper	Wrote the paper	Writing - Original Draft	YES
4951529	27435710	AS	2	developed the initial outline of the paper|provided additional detail and examples from their work	provided additional detail and examples from their work	-	-	NO
4951529	27435710	All authors	2	edited draft versions of the paper and approved the final manuscript	edited draft versions of the paper and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4951529	27435710	BL	2	provided additional detail and examples from their work	provided additional detail and examples from their work	-	-	NO
4951529	27435710	LA	2	provided additional detail and examples from their work	provided additional detail and examples from their work	-	-	NO
4951529	27435710	MK	2	provided additional detail and examples from their work	provided additional detail and examples from their work	-	-	NO
4951529	27435710	MM	2	developed the initial outline of the paper|provided additional detail and examples from their work	developed the initial outline of the paper	Wrote the paper	Writing - Original Draft	YES
4951529	27435710	MM	2	developed the initial outline of the paper|provided additional detail and examples from their work	provided additional detail and examples from their work	-	-	NO
4951529	27435710	SH	2	developed the initial outline of the paper|provided additional detail and examples from their work	developed the initial outline of the paper	Wrote the paper	Writing - Original Draft	YES
4951529	27435710	SH	2	developed the initial outline of the paper|provided additional detail and examples from their work	provided additional detail and examples from their work	-	-	NO
4491558	26185753	Omar Guzman-Ornelas	2	equally contributed to this work	equally contributed to this work	-	-	NO
4406444	25902149	DRH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406444	25902149	DRH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406444	25902149	LZ	PLoS5	Conceived and designed the experiments|Financial support	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406444	25902149	LZ	PLoS5	Conceived and designed the experiments|Financial support	Financial support	-	Funding acquisition	YES
4406444	25902149	MT	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406444	25902149	WL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406444	25902149	WL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406444	25902149	WL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406444	25902149	WL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406444	25902149	WL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406444	25902149	XLF	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406444	25902149	YYD	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406444	25902149	ZLY	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406444	25902149	ZLY	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406444	25902149	ZLY	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406444	25902149	ZLY	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5567747	28861268	AM	2	treated the patient	treated the patient	Performed the experiments	Investigation	YES
5567747	28861268	HM	2	treated the patient	treated the patient	Performed the experiments	Investigation	YES
5567747	28861268	KM	2	organized the writing of the manuscript	organized the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5567747	28861268	MH	2	organized the writing of the manuscript	organized the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5567747	28861268	NH	2	organized the writing of the manuscript	organized the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5567747	28861268	SI	2	performed the operation|treated the patient|wrote the manuscript, performed the investigation and collected the data	performed the operation	Performed the experiments	Investigation	YES
5567747	28861268	SI	2	performed the operation|treated the patient|wrote the manuscript, performed the investigation and collected the data	treated the patient	Performed the experiments	Investigation	YES
5567747	28861268	SI	2	performed the operation|treated the patient|wrote the manuscript, performed the investigation and collected the data	wrote the manuscript, performed the investigation and collected the data	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5567747	28861268	ST	2	organized the writing of the manuscript	organized the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5567747	28861268	TI	2	organized the writing of the manuscript	organized the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5567747	28861268	TM	2	performed the operation|organized the writing of the manuscript	performed the operation	Performed the experiments	Investigation	YES
5567747	28861268	TM	2	performed the operation|organized the writing of the manuscript	organized the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
4951530	27435709	AIDS	2	provided the on-site services and personnel, and contributed to programme design, data collection and analysis	provided the on-site services and personnel, and contributed to programme design, data collection and analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources|Software	YES
4951530	27435709	BL	2	conducted the officer sessions and designed and administered the officer assessments|analyzed the survey results and contributed equally to programme design and manuscript construction	conducted the officer sessions and designed and administered the officer assessments	Conceived and designed the experiments|Performed the experiments	Investigation	YES
4951530	27435709	BL	2	conducted the officer sessions and designed and administered the officer assessments|analyzed the survey results and contributed equally to programme design and manuscript construction	analyzed the survey results and contributed equally to programme design and manuscript construction	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Software	YES
4951530	27435709	BWB	2	conceptualized and implemented the programme, and obtained the ethics approvals|organized the on-site schedules and was the liaison for the probation and parole office|analyzed the survey results and contributed equally to programme design and manuscript construction	conceptualized and implemented the programme, and obtained the ethics approvals	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Project administration	YES
4951530	27435709	BWB	2	conceptualized and implemented the programme, and obtained the ethics approvals|organized the on-site schedules and was the liaison for the probation and parole office|analyzed the survey results and contributed equally to programme design and manuscript construction	organized the on-site schedules and was the liaison for the probation and parole office	-	-	NO
4951530	27435709	BWB	2	conceptualized and implemented the programme, and obtained the ethics approvals|organized the on-site schedules and was the liaison for the probation and parole office|analyzed the survey results and contributed equally to programme design and manuscript construction	analyzed the survey results and contributed equally to programme design and manuscript construction	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Software	YES
4951530	27435709	Outreach Partnership Group	2	provided the on-site services and personnel, and contributed to programme design, data collection and analysis	provided the on-site services and personnel, and contributed to programme design, data collection and analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources|Software	YES
4951530	27435709	The West Alabama	2	provided the on-site services and personnel, and contributed to programme design, data collection and analysis	provided the on-site services and personnel, and contributed to programme design, data collection and analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources|Software	YES
6164397	30042288	All authors	2	were involved in the design analysis and writing of the study	were involved in the design analysis and writing of the study	Conceived and designed the experiments|Wrote the paper	Methodology	YES
6164397	30042288	L.J.	2	performed the house calls	performed the house calls	Performed the experiments	Investigation	YES
5554365	28848567	AP	2	measured enzyme activities and carried out rt-pcr analysis|measured leaf tensile stiffness|wrote the manuscript	measured enzyme activities and carried out rt-pcr analysis	Performed the experiments	Investigation	YES
5554365	28848567	AP	2	measured enzyme activities and carried out rt-pcr analysis|measured leaf tensile stiffness|wrote the manuscript	measured leaf tensile stiffness	Performed the experiments	Investigation	YES
5554365	28848567	AP	2	measured enzyme activities and carried out rt-pcr analysis|measured leaf tensile stiffness|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5554365	28848567	BS	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5554365	28848567	DS	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5554365	28848567	JZ	2	measured leaf tensile stiffness|carried out ftir analysis	measured leaf tensile stiffness	Performed the experiments	Investigation	YES
5554365	28848567	JZ	2	measured leaf tensile stiffness|carried out ftir analysis	carried out ftir analysis	Performed the experiments	Investigation	YES
5554365	28848567	KG	2	performed afm measurements	performed afm measurements	Performed the experiments	Investigation	YES
5554365	28848567	MB	2	measured enzyme activities and carried out rt-pcr analysis	measured enzyme activities and carried out rt-pcr analysis	Performed the experiments	Investigation	YES
5554365	28848567	MO-B	2	prepared samples for ion determination	prepared samples for ion determination	Performed the experiments	Investigation	YES
5310279	28198665	CY	2	carried out experimental work for the manuscript	carried out experimental work for the manuscript	Performed the experiments	Investigation	YES
5310279	28198665	NH	2	carried out experimental work for the manuscript	carried out experimental work for the manuscript	Performed the experiments	Investigation	YES
5310279	28198665	ZY	2	carried out experimental work for the manuscript	carried out experimental work for the manuscript	Performed the experiments	Investigation	YES
4491559	26185754	Aya Obana	2	contributed equally to this work	contributed equally to this work	-	-	NO
4491559	26185754	Hitomi Ono	2	contributed equally to this work	contributed equally to this work	-	-	NO
3296173	22461980	A. Reda	2	developed the idea and involved in writing substantially	developed the idea and involved in writing substantially	Conceived and designed the experiments|Wrote the paper	Conceptualization	YES
3296173	22461980	Both authors	2	have contributed equally to the manuscript|have reviewed and approved the final draft of the paper	have contributed equally to the manuscript	-	-	NO
3296173	22461980	Both authors	2	have contributed equally to the manuscript|have reviewed and approved the final draft of the paper	have reviewed and approved the final draft of the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3296173	22461980	S. Biadgilign	2	came up with the topic of the paper and involved in writing it	came up with the topic of the paper and involved in writing it	Wrote the paper	-	YES
4406445	25902193	DQ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406445	25902193	DQ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406445	25902193	DQ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406445	25902193	JL	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4406445	25902193	JL	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4406445	25902193	JS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4406445	25902193	JS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4406445	25902193	TP	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4406445	25902193	TP	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4406445	25902193	WJ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406445	25902193	WJ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406445	25902193	WJ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406445	25902193	Y. He	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406445	25902193	Y. He	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406445	25902193	Y. Hu	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406445	25902193	Y. Hu	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406445	25902193	Y. Hu	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406445	25902193	Y. Hu	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6164409	30127287	A.M.G.	2	interpreted the data	interpreted the data	Analyzed the data	Formal analysis	YES
6164409	30127287	R.P.M.	2	interpreted the data	interpreted the data	Analyzed the data	Formal analysis	YES
6164409	30127287	W.R.D.	2	interpreted the data	interpreted the data	Analyzed the data	Formal analysis	YES
5567768	28861269	Data Analysis	2	and writing	and writing	Wrote the paper	-	YES
5577406	28878892	All authors	2	were involved equally in study design, data collection, analysis and writing	were involved equally in study design, data collection, analysis and writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology	YES
6164448	29949941	G.S.	2	provided the data and commented on the first and subsequent versions of the manuscript	provided the data and commented on the first and subsequent versions of the manuscript	Contributed reagents/materials/analysis tools	Resources	YES
6164448	29949941	H.S.	2	provided the data and commented on the first and subsequent versions of the manuscript	provided the data and commented on the first and subsequent versions of the manuscript	Contributed reagents/materials/analysis tools	Resources	YES
6164448	29949941	J.A.	2	formatted the data, wrote the manuscript and coordinated the revisions	formatted the data, wrote the manuscript and coordinated the revisions	Analyzed the data|Wrote the paper	Data curation|Project administration|Writing - Original Draft|Writing - Review & Editing	YES
6164448	29949941	T.D.	2	provided the data and commented on the first and subsequent versions of the manuscript	provided the data and commented on the first and subsequent versions of the manuscript	Contributed reagents/materials/analysis tools	Resources	YES
6164448	29949941	T.L.	2	provided the data and commented on the first and subsequent versions of the manuscript	provided the data and commented on the first and subsequent versions of the manuscript	Contributed reagents/materials/analysis tools	Resources	YES
5554372	28848587	All the authors	PLoS52	gave the final approval for submission of the manuscript	gave the final approval for submission of the manuscript	-	-	NO
5554372	28848587	DC	PLoS52	performed the data analyses and helped perform the analysis with constructive discussions	performed the data analyses and helped perform the analysis with constructive discussions	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5554372	28848587	JL	PLoS52	performed the data analyses and helped perform the analysis with constructive discussions	performed the data analyses and helped perform the analysis with constructive discussions	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5554372	28848587	QL	PLoS52	performed the data analyses and helped perform the analysis with constructive discussions	performed the data analyses and helped perform the analysis with constructive discussions	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5554372	28848587	SH	PLoS52	performed the experiments|performed the data analyses and helped perform the analysis with constructive discussions	performed the experiments	Performed the experiments	Investigation	YES
5554372	28848587	SH	PLoS52	performed the experiments|performed the data analyses and helped perform the analysis with constructive discussions	performed the data analyses and helped perform the analysis with constructive discussions	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5554372	28848587	SL	PLoS52	performed the data analyses and helped perform the analysis with constructive discussions	performed the data analyses and helped perform the analysis with constructive discussions	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5554372	28848587	SN	PLoS52	wrote the main manuscript text|contributed to the conception of the study|performed the experiments|performed the data analyses and helped perform the analysis with constructive discussions	wrote the main manuscript text	Wrote the paper	Writing - Original Draft	YES
5554372	28848587	SN	PLoS52	wrote the main manuscript text|contributed to the conception of the study|performed the experiments|performed the data analyses and helped perform the analysis with constructive discussions	contributed to the conception of the study	Conceived and designed the experiments	Conceptualization	YES
5554372	28848587	SN	PLoS52	wrote the main manuscript text|contributed to the conception of the study|performed the experiments|performed the data analyses and helped perform the analysis with constructive discussions	performed the experiments	Performed the experiments	Investigation	YES
5554372	28848587	SN	PLoS52	wrote the main manuscript text|contributed to the conception of the study|performed the experiments|performed the data analyses and helped perform the analysis with constructive discussions	performed the data analyses and helped perform the analysis with constructive discussions	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5554372	28848587	SW	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5554372	28848587	XW	PLoS52	contributed to the conception of the study	contributed to the conception of the study	Conceived and designed the experiments	Conceptualization	YES
4406446	25902182	CS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406446	25902182	CS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406446	25902182	CS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406446	25902182	DB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406446	25902182	DB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406446	25902182	DB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406446	25902182	DB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406446	25902182	ME	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406446	25902182	ME	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406446	25902182	ME	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406446	25902182	RR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406446	25902182	RR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406446	25902182	RR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406446	25902182	RR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406446	25902182	RR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406446	25902182	TH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406446	25902182	TH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406446	25902182	TH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406446	25902182	WM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406446	25902182	WM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406446	25902182	WM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406446	25902182	WM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406446	25902182	WM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4951531	27435718	AB	2	provided feedback on the draft	provided feedback on the draft	Wrote the paper	Writing - Original Draft	YES
4951531	27435718	AZ	2	provided feedback on the draft	provided feedback on the draft	Wrote the paper	Writing - Original Draft	YES
4951531	27435718	DR	2	provided feedback on the draft	provided feedback on the draft	Wrote the paper	Writing - Original Draft	YES
4951531	27435718	JC	2	incorporated feedback and editing into the manuscript	incorporated feedback and editing into the manuscript	Wrote the paper	Writing - Review & Editing	YES
4951531	27435718	NT	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5310280	28198678	CL	2	provided administrative, technical, and material support	provided administrative, technical, and material support	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Project administration|Resources	YES
5310280	28198678	GS	2	provided administrative, technical, and material support	provided administrative, technical, and material support	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Project administration|Resources	YES
5310280	28198678	JX	2	supervised the investigation	supervised the investigation	Performed the experiments	Investigation|Supervision	YES
5310280	28198678	JY	2	contributed to critical revision of the manuscript for important intellectual content	contributed to critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5310280	28198678	LY	2	conceived and designed the study, and prepared the manuscripts|carried out program testing, analyses and interpretation of data	conceived and designed the study, and prepared the manuscripts	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
5310280	28198678	LY	2	conceived and designed the study, and prepared the manuscripts|carried out program testing, analyses and interpretation of data	carried out program testing, analyses and interpretation of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5310280	28198678	QM	2	contributed to critical revision of the manuscript for important intellectual content	contributed to critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5310280	28198678	RL	2	contributed to critical revision of the manuscript for important intellectual content	contributed to critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5310280	28198678	TJ	2	provided administrative, technical, and material support	provided administrative, technical, and material support	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Project administration|Resources	YES
5310280	28198678	YK	2	conceived and designed the study, and prepared the manuscripts	conceived and designed the study, and prepared the manuscripts	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
5310280	28198678	YZ	2	contributed to the program testing	contributed to the program testing	Performed the experiments	Investigation|Software	YES
3512268	23227345	A. L. M. Verbeek	2	participated in the design, data interpretation, and critical revision of the paper	participated in the design, data interpretation, and critical revision of the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
3512268	23227345	All authors	2	contributed to the final editing and approval of the paper	contributed to the final editing and approval of the paper	Wrote the paper	Writing - Review & Editing	YES
3512268	23227345	F. A. Vostakolaei	2	participated in the design of the study, data collection, data analysis and drafting of the paper	participated in the design of the study, data collection, data analysis and drafting of the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
3512268	23227345	L. A. L. M.	2	participated in the design, data interpretation, and critical revision of the paper	participated in the design, data interpretation, and critical revision of the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
3512268	23227345	T. Feuth	2	performed statistical analysis	performed statistical analysis	Analyzed the data	Formal analysis	YES
6164486	29954090	E.L.H.Y.	2	carried out the data collection procedures	carried out the data collection procedures	Performed the experiments	Investigation	YES
6164486	29954090	L.S.C.L.	2	participated in the analysis of the data	participated in the analysis of the data	Analyzed the data	Formal analysis	YES
6164486	29954090	L.W.S.	2	carried out the data collection procedures	carried out the data collection procedures	Performed the experiments	Investigation	YES
6164486	29954090	L.Y.S.	2	carried out the data collection procedures	carried out the data collection procedures	Performed the experiments	Investigation	YES
6164486	29954090	S.H.Q.	2	carried out the data collection procedures	carried out the data collection procedures	Performed the experiments	Investigation	YES
6164486	29954090	S.P.	2	conceived and designed the study and wrote the paper	conceived and designed the study and wrote the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
6164486	29954090	T.W.L.	2	participated in the analysis of the data	participated in the analysis of the data	Analyzed the data	Formal analysis	YES
6164486	29954090	Y.N.C.	2	participated in the analysis of the data	participated in the analysis of the data	Analyzed the data	Formal analysis	YES
5554398	28848598	HG	2	carried out allele identification and function analysis|developed the mutated population	carried out allele identification and function analysis	Performed the experiments	Investigation	YES
5554398	28848598	HG	2	carried out allele identification and function analysis|developed the mutated population	developed the mutated population	-	-	NO
5554398	28848598	JG	2	developed the mutated population	developed the mutated population	-	-	NO
5554398	28848598	LL	2	conceived the original research, supervised data generation and analyses and wrote the manuscript	conceived the original research, supervised data generation and analyses and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Supervision|Writing - Original Draft	YES
5554398	28848598	LZ	2	developed the mutated population	developed the mutated population	-	-	NO
5554398	28848598	SZ	2	developed the mutated population	developed the mutated population	-	-	NO
5554398	28848598	XL	2	carried out allele identification and function analysis	carried out allele identification and function analysis	Performed the experiments	Investigation	YES
5554398	28848598	YL	2	carried out allele identification and function analysis	carried out allele identification and function analysis	Performed the experiments	Investigation	YES
5554398	28848598	YX	2	developed the mutated population	developed the mutated population	-	-	NO
5554398	28848598	ZY	2	carried out allele identification and function analysis	carried out allele identification and function analysis	Performed the experiments	Investigation	YES
4951532	27435711	All authors	2	read and assisted in editing the manuscript	read and assisted in editing the manuscript	Wrote the paper	Writing - Review & Editing	YES
5764602	29416198	All authors	2	participated in each step of research|gave final approval for final version to be submitted	participated in each step of research	-	-	NO
5764602	29416198	All authors	2	participated in each step of research|gave final approval for final version to be submitted	gave final approval for final version to be submitted	-	-	NO
4406447	25902334	CMC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406447	25902334	CMC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406447	25902334	CMC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406447	25902334	LH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406447	25902334	LH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406447	25902334	LH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406447	25902334	LH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5310281	28198672	All authors	PLoS52	contributed to and approved the final manuscript	contributed to and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5310281	28198672	DA	PLoS52	conceived and designed the study|analyzed the data	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5310281	28198672	DA	PLoS52	conceived and designed the study|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5310281	28198672	LCX	PLoS52	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5310281	28198672	RH	PLoS52	conceived and designed the study|analyzed the data	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5310281	28198672	RH	PLoS52	conceived and designed the study|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5554512	28848591	AP-C	2	supervised the research design and wrote the manuscript	supervised the research design and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Supervision|Writing - Original Draft	YES
5554512	28848591	All authors	2	discussed the results and commented on the manuscript	discussed the results and commented on the manuscript	-	-	NO
5554512	28848591	MD	2	performed molecular experiments	performed molecular experiments	Performed the experiments	Investigation	YES
6164525	29970795	Each author	2	contributed substantially to the writing of this editorial	contributed substantially to the writing of this editorial	Wrote the paper	Writing - Review & Editing	YES
4491566	26185758	Fu Wei-Lin	2	contributed equally to this work	contributed equally to this work	-	-	NO
4491566	26185758	Sun Sheng-Ren	2	contributed equally to this work	contributed equally to this work	-	-	NO
5596353	28932394	All	1	Data interpretation	Data interpretation	Analyzed the data	Formal analysis	YES
5596353	28932394	HA	1	Review	Review	-	-	NO
5596353	28932394	KF	1	Data collection	Data collection	Performed the experiments	Investigation	YES
5596353	28932394	MT	1	Data analysis/interpretation|Paper writing|Review	Data analysis/interpretation	Analyzed the data	Formal analysis	YES
5596353	28932394	MT	1	Data analysis/interpretation|Paper writing|Review	Paper writing	Wrote the paper	-	YES
5596353	28932394	MT	1	Data analysis/interpretation|Paper writing|Review	Review	-	-	NO
5596353	28932394	MW	1	Study design|Data collection|Data analysis/interpretation|Paper writing	Study design	Conceived and designed the experiments	Methodology	YES
5596353	28932394	MW	1	Study design|Data collection|Data analysis/interpretation|Paper writing	Data collection	Performed the experiments	Investigation	YES
5596353	28932394	MW	1	Study design|Data collection|Data analysis/interpretation|Paper writing	Data analysis/interpretation	Analyzed the data	Formal analysis	YES
5596353	28932394	MW	1	Study design|Data collection|Data analysis/interpretation|Paper writing	Paper writing	Wrote the paper	-	YES
6164552	30134511	F.A.	2	contributed to study conceptualization, design of methodology, interview schedule validation, investigation, formal analysis, and writing--review & editing	contributed to study conceptualization, design of methodology, interview schedule validation, investigation, formal analysis, and writing--review & editing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Validation|Writing - Review & Editing	YES
6164552	30134511	N.S.	2	contributed to study conceptualization, design of methodology, writing--original draft preparation, and writing--review & editing	contributed to study conceptualization, design of methodology, writing--original draft preparation, and writing--review & editing	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
6164552	30134511	R.K.	2	contributed to study conceptualization, design of methodology, interview schedule validation, investigation, formal analysis, and writing--review & editing|also contributed to data curation, supervision, and project administration	contributed to study conceptualization, design of methodology, interview schedule validation, investigation, formal analysis, and writing--review & editing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Validation|Writing - Review & Editing	YES
6164552	30134511	R.K.	2	contributed to study conceptualization, design of methodology, interview schedule validation, investigation, formal analysis, and writing--review & editing|also contributed to data curation, supervision, and project administration	also contributed to data curation, supervision, and project administration	Analyzed the data	Data curation|Project administration|Supervision	YES
6164552	30134511	V.S.	2	contributed to formal analysis, data curation, writing--original draft preparation, and writing--review & editing	contributed to formal analysis, data curation, writing--original draft preparation, and writing--review & editing	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Data curation|Formal analysis|Resources|Writing - Original Draft|Writing - Review & Editing	YES
4951533	27435717	AM	2	was involved with the study design, survey construction, data collection and data analysis, as well as writing and reviewing the manuscript	was involved with the study design, survey construction, data collection and data analysis, as well as writing and reviewing the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
4951533	27435717	AZ	2	were involved in the data interpretation and analysis, as well as writing and reviewing the manuscript	were involved in the data interpretation and analysis, as well as writing and reviewing the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
4951533	27435717	FLA	2	were involved with the study design, survey construction and data analysis, as well as writing and reviewing the manuscript|were involved in the data interpretation and analysis, as well as writing and reviewing the manuscript|was the principal investigator and was involved in the study design, survey construction and data interpretation, as well as writing and reviewing the manuscript	were involved with the study design, survey construction and data analysis, as well as writing and reviewing the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
4951533	27435717	FLA	2	were involved with the study design, survey construction and data analysis, as well as writing and reviewing the manuscript|were involved in the data interpretation and analysis, as well as writing and reviewing the manuscript|was the principal investigator and was involved in the study design, survey construction and data interpretation, as well as writing and reviewing the manuscript	were involved in the data interpretation and analysis, as well as writing and reviewing the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
4951533	27435717	FLA	2	were involved with the study design, survey construction and data analysis, as well as writing and reviewing the manuscript|were involved in the data interpretation and analysis, as well as writing and reviewing the manuscript|was the principal investigator and was involved in the study design, survey construction and data interpretation, as well as writing and reviewing the manuscript	was the principal investigator and was involved in the study design, survey construction and data interpretation, as well as writing and reviewing the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Funding acquisition|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
4951533	27435717	MJB	2	were involved with the study design, survey construction and data analysis, as well as writing and reviewing the manuscript	were involved with the study design, survey construction and data analysis, as well as writing and reviewing the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
4951533	27435717	OK	2	was responsible for conceptualizing and conducting the analysis, as well as writing and reviewing the manuscript	was responsible for conceptualizing and conducting the analysis, as well as writing and reviewing the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
4951533	27435717	RM	2	were involved with the study design, survey construction and data analysis, as well as writing and reviewing the manuscript	were involved with the study design, survey construction and data analysis, as well as writing and reviewing the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
4951533	27435717	SD	2	was involved in the study design and manuscript review	was involved in the study design and manuscript review	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
4951533	27435717	SF	2	was a site co-investigator from the icf alliance for public health in ukraine and was involved in the study design and manuscript review	was a site co-investigator from the icf alliance for public health in ukraine and was involved in the study design and manuscript review	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
3628659	23606813	B. Arlet	2	contributed equally to this work	contributed equally to this work	-	-	NO
3628659	23606813	G. Courtois	2	contributed equally to this work	contributed equally to this work	-	-	NO
3628659	23606813	O. Hermine	2	contributed equally to this work	contributed equally to this work	-	-	NO
5554516	28848570	A-SX	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Revised the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5554516	28848570	A-SX	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Revised the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5554516	28848570	A-SX	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Revised the paper	Revised the paper	Wrote the paper	Writing - Review & Editing	YES
5554516	28848570	FQ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5554516	28848570	FQ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
5554516	28848570	FQ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5554516	28848570	FQ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5554516	28848570	FW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5554516	28848570	G-LW	PLoS5	Performed the experiments|Analyzed the data|Revised the paper	Performed the experiments	Performed the experiments	Investigation	YES
5554516	28848570	G-LW	PLoS5	Performed the experiments|Analyzed the data|Revised the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5554516	28848570	G-LW	PLoS5	Performed the experiments|Analyzed the data|Revised the paper	Revised the paper	Wrote the paper	Writing - Review & Editing	YES
5554516	28848570	Z-SX	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5310283	28198667	All authors	2	contributed to the revision of the work	contributed to the revision of the work	Wrote the paper	Writing - Review & Editing	YES
5310283	28198667	JZ	2	processed all tcga data and performed all computational analysis and wrote the manuscript	processed all tcga data and performed all computational analysis and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Formal analysis|Investigation|Writing - Original Draft	YES
5310283	28198667	KH	2	designed the study, wrote the code for lmqcm algorithm and involved in results interpretation and discussion	designed the study, wrote the code for lmqcm algorithm and involved in results interpretation and discussion	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Software|Writing - Original Draft	YES
5602742	28948022	AL	2	helped in drafting the manuscript and interpretation of data|edited the manuscript	helped in drafting the manuscript and interpretation of data	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5602742	28948022	AL	2	helped in drafting the manuscript and interpretation of data|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5602742	28948022	All authors	2	in this manuscript contributed to the design of the study, analysis/interpretation of data, and drafting of this manuscript	in this manuscript contributed to the design of the study, analysis/interpretation of data, and drafting of this manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Original Draft	YES
5602742	28948022	J.K.	2	edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5602742	28948022	M.N.	2	collected questionnaires	collected questionnaires	Performed the experiments	Investigation	YES
5602742	28948022	N.S.	2	edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5602742	28948022	S.S.	2	collected questionnaires|obtained the written informed consent from the patients|performed statistical analysis	collected questionnaires	Performed the experiments	Investigation	YES
5602742	28948022	S.S.	2	collected questionnaires|obtained the written informed consent from the patients|performed statistical analysis	obtained the written informed consent from the patients	Wrote the paper	Project administration|Writing - Original Draft	YES
5602742	28948022	S.S.	2	collected questionnaires|obtained the written informed consent from the patients|performed statistical analysis	performed statistical analysis	Analyzed the data	Formal analysis	YES
5602742	28948022	Y.H.	2	obtained the written informed consent from the patients	obtained the written informed consent from the patients	Wrote the paper	Project administration|Writing - Original Draft	YES
5602742	28948022	Y.S.	2	performed statistical analysis	performed statistical analysis	Analyzed the data	Formal analysis	YES
4406448	25902009	BP	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406448	25902009	BP	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4406448	25902009	BP	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406448	25902009	BR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406448	25902009	BR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406448	25902009	BR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406448	25902009	BR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406448	25902009	BR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406448	25902009	CGG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406448	25902009	CGG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406448	25902009	CGG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406448	25902009	CGG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406448	25902009	CGG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406448	25902009	LH	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406448	25902009	LH	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4406448	25902009	MM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406448	25902009	MM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4406448	25902009	MM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406448	25902009	OZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406448	25902009	OZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4406448	25902009	OZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4406448	25902009	OZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406448	25902009	SF	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406448	25902009	SF	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4951534	27435719	DP	2	both authors provided equal input to the article	both authors provided equal input to the article	-	-	NO
4951534	27435719	NC	2	both authors provided equal input to the article	both authors provided equal input to the article	-	-	NO
5310284	28198671	CJ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5310284	28198671	CJ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5310284	28198671	FL	PLoS5	Provided comments on the manuscript	Provided comments on the manuscript	-	-	NO
5310284	28198671	JJ	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
5310284	28198671	JJ	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5310284	28198671	JW	PLoS5	Provided comments on the manuscript	Provided comments on the manuscript	-	-	NO
5310284	28198671	JX	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Provided comments on the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5310284	28198671	JX	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Provided comments on the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5310284	28198671	JX	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Provided comments on the manuscript	Provided comments on the manuscript	-	-	NO
5310284	28198671	MC	PLoS5	Provided comments on the manuscript	Provided comments on the manuscript	-	-	NO
5310284	28198671	RL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5310284	28198671	RL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5310284	28198671	RL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5310284	28198671	RZ	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5310284	28198671	WD	PLoS5	Provided comments on the manuscript	Provided comments on the manuscript	-	-	NO
5310284	28198671	WS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5310284	28198671	WS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5310284	28198671	WS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5310284	28198671	XG	PLoS5	Analyzed the data|Provided comments on the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
5310284	28198671	XG	PLoS5	Analyzed the data|Provided comments on the manuscript	Provided comments on the manuscript	-	-	NO
5310284	28198671	XS	PLoS5	Provided comments on the manuscript	Provided comments on the manuscript	-	-	NO
5557727	28855910	AN	2	had major and equal contribution in overall preparation of manuscript|has collected research data and compiled manuscript	had major and equal contribution in overall preparation of manuscript	Wrote the paper	Writing - Original Draft	YES
5557727	28855910	AN	2	had major and equal contribution in overall preparation of manuscript|has collected research data and compiled manuscript	has collected research data and compiled manuscript	Performed the experiments	Investigation	YES
5557727	28855910	HK	2	contributed in writing the different sections	contributed in writing the different sections	Wrote the paper	Writing - Original Draft	YES
5557727	28855910	MA	2	had major and equal contribution in overall preparation of manuscript|has made all the figures and tables and made corrections	had major and equal contribution in overall preparation of manuscript	Wrote the paper	Writing - Original Draft	YES
5557727	28855910	MA	2	had major and equal contribution in overall preparation of manuscript|has made all the figures and tables and made corrections	has made all the figures and tables and made corrections	-	Visualization	YES
5557727	28855910	NK	2	contributed in writing the different sections	contributed in writing the different sections	Wrote the paper	Writing - Original Draft	YES
5557727	28855910	SH	2	has provided technical guidance and critically read this manuscript and suggested for improvement and corrected mistakes	has provided technical guidance and critically read this manuscript and suggested for improvement and corrected mistakes	Wrote the paper	Supervision|Writing - Review & Editing	YES
5557727	28855910	TS	2	have compiled table	have compiled table	-	-	NO
6164702	30200579	H.T.	2	supervised data handling and the analysis	supervised data handling and the analysis	Analyzed the data	Data curation|Formal analysis|Supervision	YES
6164702	30200579	K.K.	2	planed the study design and conducted the study	planed the study design and conducted the study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6164702	30200579	M.H.	2	distributed and collected questionnaire	distributed and collected questionnaire	Performed the experiments	Investigation	YES
6164702	30200579	M.N.-T.	2	planed the study design and conducted the study|distributed and collected questionnaire	planed the study design and conducted the study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6164702	30200579	M.N.-T.	2	planed the study design and conducted the study|distributed and collected questionnaire	distributed and collected questionnaire	Performed the experiments	Investigation	YES
6164702	30200579	N.Y.	2	planed the study design and conducted the study	planed the study design and conducted the study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6164702	30200579	Y.M.	2	analyzed the data and drafted the manuscript	analyzed the data and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4493267	26199934	Dong Hyun Kim	2	contributed equally to this work	contributed equally to this work	-	-	NO
4493267	26199934	Sang Kon Lee	2	contributed equally to this work	contributed equally to this work	-	-	NO
4951535	27435714	All authors	PLoS52	reviewed and approved the final manuscript	reviewed and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4951535	27435714	BW	PLoS52	drafted the manuscript with contributions from the remaining co-authors	drafted the manuscript with contributions from the remaining co-authors	Wrote the paper	Writing - Original Draft	YES
4951535	27435714	CD	PLoS52	contributed significantly to the study design|conceived the study	contributed significantly to the study design	Conceived and designed the experiments	Methodology	YES
4951535	27435714	CD	PLoS52	contributed significantly to the study design|conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4951535	27435714	CZ	PLoS52	contributed significantly to the study design|conducted the observation and interviews|analyzed the data|drafted the manuscript with contributions from the remaining co-authors	contributed significantly to the study design	Conceived and designed the experiments	Methodology	YES
4951535	27435714	CZ	PLoS52	contributed significantly to the study design|conducted the observation and interviews|analyzed the data|drafted the manuscript with contributions from the remaining co-authors	conducted the observation and interviews	Performed the experiments	Investigation	YES
4951535	27435714	CZ	PLoS52	contributed significantly to the study design|conducted the observation and interviews|analyzed the data|drafted the manuscript with contributions from the remaining co-authors	analyzed the data	Analyzed the data	Formal analysis	YES
4951535	27435714	CZ	PLoS52	contributed significantly to the study design|conducted the observation and interviews|analyzed the data|drafted the manuscript with contributions from the remaining co-authors	drafted the manuscript with contributions from the remaining co-authors	Wrote the paper	Writing - Original Draft	YES
4951535	27435714	GM	PLoS52	drafted the manuscript with contributions from the remaining co-authors	drafted the manuscript with contributions from the remaining co-authors	Wrote the paper	Writing - Original Draft	YES
4951535	27435714	GR	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
4951535	27435714	HY	PLoS52	contributed significantly to the study design|analyzed the data	contributed significantly to the study design	Conceived and designed the experiments	Methodology	YES
4951535	27435714	HY	PLoS52	contributed significantly to the study design|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
4951535	27435714	QH	PLoS52	contributed significantly to the study design|conceived the study	contributed significantly to the study design	Conceived and designed the experiments	Methodology	YES
4951535	27435714	QH	PLoS52	contributed significantly to the study design|conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4951535	27435714	TC	PLoS52	contributed significantly to the study design|conceived the study	contributed significantly to the study design	Conceived and designed the experiments	Methodology	YES
4951535	27435714	TC	PLoS52	contributed significantly to the study design|conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4951535	27435714	TL	PLoS52	contributed significantly to the study design|conceived the study	contributed significantly to the study design	Conceived and designed the experiments	Methodology	YES
4951535	27435714	TL	PLoS52	contributed significantly to the study design|conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4951535	27435714	YM	PLoS52	contributed significantly to the study design|conceived the study|analyzed the data	contributed significantly to the study design	Conceived and designed the experiments	Methodology	YES
4951535	27435714	YM	PLoS52	contributed significantly to the study design|conceived the study|analyzed the data	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4951535	27435714	YM	PLoS52	contributed significantly to the study design|conceived the study|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5557779	28855914	All authors	PLoS52	have read, edited and approved the current version of the manuscript	have read, edited and approved the current version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5557779	28855914	JW	PLoS52	performed marker development and mapping analysis	performed marker development and mapping analysis	Performed the experiments	Investigation	YES
5557779	28855914	JY	PLoS52	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5557779	28855914	QJ	PLoS52	designed the experiments|performed marker development and mapping analysis|wrote the paper	designed the experiments	Conceived and designed the experiments	Methodology	YES
5557779	28855914	QJ	PLoS52	designed the experiments|performed marker development and mapping analysis|wrote the paper	performed marker development and mapping analysis	Performed the experiments	Investigation	YES
5557779	28855914	QJ	PLoS52	designed the experiments|performed marker development and mapping analysis|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5557779	28855914	WH	PLoS52	conducted bioinformatic analysis of snp data	conducted bioinformatic analysis of snp data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5557779	28855914	ZL	PLoS52	designed the experiments|wrote the paper	designed the experiments	Conceived and designed the experiments	Methodology	YES
5557779	28855914	ZL	PLoS52	designed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6164835	30154389	J.M.L.	1	Conception and design|Collection and interpretation|Drafting manuscript|Manuscript revision and approval of final version of manuscript for publication	Conception and design	Conceived and designed the experiments	Conceptualization	YES
6164835	30154389	J.M.L.	1	Conception and design|Collection and interpretation|Drafting manuscript|Manuscript revision and approval of final version of manuscript for publication	Collection and interpretation	Analyzed the data	Formal analysis	YES
6164835	30154389	J.M.L.	1	Conception and design|Collection and interpretation|Drafting manuscript|Manuscript revision and approval of final version of manuscript for publication	Drafting manuscript	Wrote the paper	Writing - Original Draft	YES
6164835	30154389	J.M.L.	1	Conception and design|Collection and interpretation|Drafting manuscript|Manuscript revision and approval of final version of manuscript for publication	Manuscript revision and approval of final version of manuscript for publication	Wrote the paper	Writing - Review & Editing	YES
6164835	30154389	M.C.M.	1	Conception and design|Collection and interpretation|Drafting manuscript|Manuscript revision and approval of final version of manuscript for publication	Conception and design	Conceived and designed the experiments	Conceptualization	YES
6164835	30154389	M.C.M.	1	Conception and design|Collection and interpretation|Drafting manuscript|Manuscript revision and approval of final version of manuscript for publication	Collection and interpretation	Analyzed the data	Formal analysis	YES
6164835	30154389	M.C.M.	1	Conception and design|Collection and interpretation|Drafting manuscript|Manuscript revision and approval of final version of manuscript for publication	Drafting manuscript	Wrote the paper	Writing - Original Draft	YES
6164835	30154389	M.C.M.	1	Conception and design|Collection and interpretation|Drafting manuscript|Manuscript revision and approval of final version of manuscript for publication	Manuscript revision and approval of final version of manuscript for publication	Wrote the paper	Writing - Review & Editing	YES
6164835	30154389	N.W.L.	1	Conception and design|Collection and interpretation|Drafting manuscript|Manuscript revision and approval of final version of manuscript for publication	Conception and design	Conceived and designed the experiments	Conceptualization	YES
6164835	30154389	N.W.L.	1	Conception and design|Collection and interpretation|Drafting manuscript|Manuscript revision and approval of final version of manuscript for publication	Collection and interpretation	Analyzed the data	Formal analysis	YES
6164835	30154389	N.W.L.	1	Conception and design|Collection and interpretation|Drafting manuscript|Manuscript revision and approval of final version of manuscript for publication	Drafting manuscript	Wrote the paper	Writing - Original Draft	YES
6164835	30154389	N.W.L.	1	Conception and design|Collection and interpretation|Drafting manuscript|Manuscript revision and approval of final version of manuscript for publication	Manuscript revision and approval of final version of manuscript for publication	Wrote the paper	Writing - Review & Editing	YES
6164835	30154389	R.D.	1	Collection and interpretation|Manuscript revision and approval of final version of manuscript for publication	Collection and interpretation	Analyzed the data	Formal analysis	YES
6164835	30154389	R.D.	1	Collection and interpretation|Manuscript revision and approval of final version of manuscript for publication	Manuscript revision and approval of final version of manuscript for publication	Wrote the paper	Writing - Review & Editing	YES
6164835	30154389	R.G.B.	1	Conception and design|Collection and interpretation|Manuscript revision and approval of final version of manuscript for publication	Conception and design	Conceived and designed the experiments	Conceptualization	YES
6164835	30154389	R.G.B.	1	Conception and design|Collection and interpretation|Manuscript revision and approval of final version of manuscript for publication	Collection and interpretation	Analyzed the data	Formal analysis	YES
6164835	30154389	R.G.B.	1	Conception and design|Collection and interpretation|Manuscript revision and approval of final version of manuscript for publication	Manuscript revision and approval of final version of manuscript for publication	Wrote the paper	Writing - Review & Editing	YES
6164835	30154389	R.W.S.	1	Conception and design|Collection and interpretation|Manuscript revision and approval of final version of manuscript for publication	Conception and design	Conceived and designed the experiments	Conceptualization	YES
6164835	30154389	R.W.S.	1	Conception and design|Collection and interpretation|Manuscript revision and approval of final version of manuscript for publication	Collection and interpretation	Analyzed the data	Formal analysis	YES
6164835	30154389	R.W.S.	1	Conception and design|Collection and interpretation|Manuscript revision and approval of final version of manuscript for publication	Manuscript revision and approval of final version of manuscript for publication	Wrote the paper	Writing - Review & Editing	YES
6164835	30154389	V.W.S.	1	Conception and design|Collection and interpretation|Drafting manuscript|Manuscript revision and approval of final version of manuscript for publication	Conception and design	Conceived and designed the experiments	Conceptualization	YES
6164835	30154389	V.W.S.	1	Conception and design|Collection and interpretation|Drafting manuscript|Manuscript revision and approval of final version of manuscript for publication	Collection and interpretation	Analyzed the data	Formal analysis	YES
6164835	30154389	V.W.S.	1	Conception and design|Collection and interpretation|Drafting manuscript|Manuscript revision and approval of final version of manuscript for publication	Drafting manuscript	Wrote the paper	Writing - Original Draft	YES
6164835	30154389	V.W.S.	1	Conception and design|Collection and interpretation|Drafting manuscript|Manuscript revision and approval of final version of manuscript for publication	Manuscript revision and approval of final version of manuscript for publication	Wrote the paper	Writing - Review & Editing	YES
5310285	28198675	GW	2	helped to test the algorithm	helped to test the algorithm	Contributed reagents/materials/analysis tools	Software	YES
5310285	28198675	HX	2	helped to test the algorithm	helped to test the algorithm	Contributed reagents/materials/analysis tools	Software	YES
5310285	28198675	JC	2	conceived the project|designed the algorithm and experiments|wrote this manuscript	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5310285	28198675	JC	2	conceived the project|designed the algorithm and experiments|wrote this manuscript	designed the algorithm and experiments	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Methodology|Software	YES
5310285	28198675	JC	2	conceived the project|designed the algorithm and experiments|wrote this manuscript	wrote this manuscript	Wrote the paper	Writing - Original Draft	YES
5310285	28198675	JP	2	conceived the project|designed the algorithm and experiments|wrote this manuscript	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5310285	28198675	JP	2	conceived the project|designed the algorithm and experiments|wrote this manuscript	designed the algorithm and experiments	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Methodology|Software	YES
5310285	28198675	JP	2	conceived the project|designed the algorithm and experiments|wrote this manuscript	wrote this manuscript	Wrote the paper	Writing - Original Draft	YES
5310285	28198675	KB	2	designed the algorithm and experiments	designed the algorithm and experiments	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Methodology|Software	YES
5310285	28198675	LC	2	helped to test the algorithm	helped to test the algorithm	Contributed reagents/materials/analysis tools	Software	YES
5310285	28198675	SJ	2	helped to test the algorithm	helped to test the algorithm	Contributed reagents/materials/analysis tools	Software	YES
5310285	28198675	XS	2	helped to test the algorithm	helped to test the algorithm	Contributed reagents/materials/analysis tools	Software	YES
5310285	28198675	YW	2	conceived the project	conceived the project	Conceived and designed the experiments	Conceptualization	YES
4406449	25901605	AN	PLoS5	Analyzed the data|Wrote the paper|Conducted laboratory work	Analyzed the data	Analyzed the data	Formal analysis	YES
4406449	25901605	AN	PLoS5	Analyzed the data|Wrote the paper|Conducted laboratory work	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406449	25901605	AN	PLoS5	Analyzed the data|Wrote the paper|Conducted laboratory work	Conducted laboratory work	Performed the experiments	Investigation	YES
4406449	25901605	BAL	PLoS5	Analyzed the data|Wrote the paper|Conducted in situ measurements and sample collection/processing|Conducted laboratory work	Analyzed the data	Analyzed the data	Formal analysis	YES
4406449	25901605	BAL	PLoS5	Analyzed the data|Wrote the paper|Conducted in situ measurements and sample collection/processing|Conducted laboratory work	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406449	25901605	BAL	PLoS5	Analyzed the data|Wrote the paper|Conducted in situ measurements and sample collection/processing|Conducted laboratory work	Conducted in situ measurements and sample collection/processing	Performed the experiments	Data curation|Investigation	YES
4406449	25901605	BAL	PLoS5	Analyzed the data|Wrote the paper|Conducted in situ measurements and sample collection/processing|Conducted laboratory work	Conducted laboratory work	Performed the experiments	Investigation	YES
4406449	25901605	CH	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Conducted in situ measurements and sample collection/processing	Analyzed the data	Analyzed the data	Formal analysis	YES
4406449	25901605	CH	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Conducted in situ measurements and sample collection/processing	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406449	25901605	CH	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Conducted in situ measurements and sample collection/processing	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406449	25901605	CH	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Conducted in situ measurements and sample collection/processing	Conducted in situ measurements and sample collection/processing	Performed the experiments	Data curation|Investigation	YES
4406449	25901605	CM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Conducted laboratory work	Analyzed the data	Analyzed the data	Formal analysis	YES
4406449	25901605	CM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Conducted laboratory work	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406449	25901605	CM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Conducted laboratory work	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406449	25901605	CM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Conducted laboratory work	Conducted laboratory work	Performed the experiments	Investigation	YES
4406449	25901605	GM	PLoS5	Analyzed the data|Wrote the paper|Conducted laboratory work	Analyzed the data	Analyzed the data	Formal analysis	YES
4406449	25901605	GM	PLoS5	Analyzed the data|Wrote the paper|Conducted laboratory work	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406449	25901605	GM	PLoS5	Analyzed the data|Wrote the paper|Conducted laboratory work	Conducted laboratory work	Performed the experiments	Investigation	YES
4406449	25901605	HF	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406449	25901605	HF	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406449	25901605	HF	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406449	25901605	IH	PLoS5	Analyzed the data|Wrote the paper|Conducted in situ measurements and sample collection/processing	Analyzed the data	Analyzed the data	Formal analysis	YES
4406449	25901605	IH	PLoS5	Analyzed the data|Wrote the paper|Conducted in situ measurements and sample collection/processing	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406449	25901605	IH	PLoS5	Analyzed the data|Wrote the paper|Conducted in situ measurements and sample collection/processing	Conducted in situ measurements and sample collection/processing	Performed the experiments	Data curation|Investigation	YES
4406449	25901605	JAC	PLoS5	Analyzed the data|Wrote the paper|Conducted in situ measurements and sample collection/processing	Analyzed the data	Analyzed the data	Formal analysis	YES
4406449	25901605	JAC	PLoS5	Analyzed the data|Wrote the paper|Conducted in situ measurements and sample collection/processing	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406449	25901605	JAC	PLoS5	Analyzed the data|Wrote the paper|Conducted in situ measurements and sample collection/processing	Conducted in situ measurements and sample collection/processing	Performed the experiments	Data curation|Investigation	YES
4406449	25901605	JB	PLoS5	Analyzed the data|Wrote the paper|Conducted in situ measurements and sample collection/processing	Analyzed the data	Analyzed the data	Formal analysis	YES
4406449	25901605	JB	PLoS5	Analyzed the data|Wrote the paper|Conducted in situ measurements and sample collection/processing	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406449	25901605	JB	PLoS5	Analyzed the data|Wrote the paper|Conducted in situ measurements and sample collection/processing	Conducted in situ measurements and sample collection/processing	Performed the experiments	Data curation|Investigation	YES
5612789	28970942	Ali Ramouz	7	study design, data collections, writing	study design, data collections, writing	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology	YES
5612789	28970942	Esmaeil Faraji	7	data collections, writing	data collections, writing	Performed the experiments|Wrote the paper	Investigation	YES
5612789	28970942	Faeze Daghigh	7	Data analysis, data collections	Data analysis, data collections	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5612789	28970942	Seyed Ziaeddin Rasihashemi	7	study design, data acquisition, drafting	study design, data acquisition, drafting	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5612789	28970942	Shahin Rouhani	7	data analysis, writing, drafting	data analysis, writing, drafting	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5764614	29416199	Enes Osmanovic	2	gave contribution to acquisition of data	gave contribution to acquisition of data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5764614	29416199	Nedzad Kadric	2	gave contribution to acquisition of data	gave contribution to acquisition of data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4951536	27435708	All authors	2	have reviewed and approved the final manuscript	have reviewed and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4951536	27435708	BKV	2	were integral in its implementation	were integral in its implementation	Performed the experiments	Investigation	YES
4951536	27435708	JFB	2	were involved in the survey design and analysis	were involved in the survey design and analysis	Conceived and designed the experiments|Performed the experiments	Investigation	YES
4951536	27435708	LMM	2	were involved equally in the development of this manuscript	were involved equally in the development of this manuscript	Wrote the paper	Writing - Original Draft	YES
4951536	27435708	PB	2	were involved equally in the development of this manuscript	were involved equally in the development of this manuscript	Wrote the paper	Writing - Original Draft	YES
4951536	27435708	SI	2	were involved equally in the development of this manuscript|were involved in the survey design and analysis	were involved equally in the development of this manuscript	Wrote the paper	Writing - Original Draft	YES
4951536	27435708	SI	2	were involved equally in the development of this manuscript|were involved in the survey design and analysis	were involved in the survey design and analysis	Conceived and designed the experiments|Performed the experiments	Investigation	YES
4951536	27435708	SJ	2	were integral in its implementation	were integral in its implementation	Performed the experiments	Investigation	YES
6164845	30049965	B.V.R.	2	contributed to conception of the study design|revised the manuscript	contributed to conception of the study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6164845	30049965	B.V.R.	2	contributed to conception of the study design|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
6164845	30049965	K.B.	2	contributed to conception of the study design|revised the manuscript	contributed to conception of the study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6164845	30049965	K.B.	2	contributed to conception of the study design|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
6164845	30049965	T.D.	2	contributed to conception of the study design|supported inclusion of the participants and data collection|analyzed and interpreted the data|revised the manuscript	contributed to conception of the study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6164845	30049965	T.D.	2	contributed to conception of the study design|supported inclusion of the participants and data collection|analyzed and interpreted the data|revised the manuscript	supported inclusion of the participants and data collection	Performed the experiments	Investigation	YES
6164845	30049965	T.D.	2	contributed to conception of the study design|supported inclusion of the participants and data collection|analyzed and interpreted the data|revised the manuscript	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
6164845	30049965	T.D.	2	contributed to conception of the study design|supported inclusion of the participants and data collection|analyzed and interpreted the data|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
6164845	30049965	T.V.	2	contributed to conception of the study design|supported inclusion of the participants and data collection|analyzed and interpreted the data|drafted and wrote the original manuscript|revised the manuscript	contributed to conception of the study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6164845	30049965	T.V.	2	contributed to conception of the study design|supported inclusion of the participants and data collection|analyzed and interpreted the data|drafted and wrote the original manuscript|revised the manuscript	supported inclusion of the participants and data collection	Performed the experiments	Investigation	YES
6164845	30049965	T.V.	2	contributed to conception of the study design|supported inclusion of the participants and data collection|analyzed and interpreted the data|drafted and wrote the original manuscript|revised the manuscript	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
6164845	30049965	T.V.	2	contributed to conception of the study design|supported inclusion of the participants and data collection|analyzed and interpreted the data|drafted and wrote the original manuscript|revised the manuscript	drafted and wrote the original manuscript	Wrote the paper	Writing - Original Draft	YES
6164845	30049965	T.V.	2	contributed to conception of the study design|supported inclusion of the participants and data collection|analyzed and interpreted the data|drafted and wrote the original manuscript|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4493286	26199937	Anna Lewinska	2	carried out data interpretation and wrote the paper	carried out data interpretation and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4493286	26199937	Jacek Zebrowski	2	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4493286	26199937	Jennifer Mytych	2	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4493286	26199937	Maciej Wnuk	2	carried out data interpretation and conceived and designed the experiments	carried out data interpretation and conceived and designed the experiments	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
5633336	29021898	Emma Pope	1	Other contributors	Other contributors	-	-	NO
5633336	29021898	Hannah Courtney	1	Writers	Writers	Wrote the paper	-	YES
5633336	29021898	James Williamson	1	Other contributors	Other contributors	-	-	NO
5633336	29021898	Manon Jenkins	1	Writers	Writers	Wrote the paper	-	YES
5557787	28855915	AP	PLoS52	analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5557787	28855915	AP	PLoS52	analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5557787	28855915	AV	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5557787	28855915	SE	PLoS52	analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5557787	28855915	SE	PLoS52	analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5770196	29416200	AG	1	Conception and design|Drafting the article	Conception and design	Conceived and designed the experiments	Conceptualization	YES
5770196	29416200	AG	1	Conception and design|Drafting the article	Drafting the article	Wrote the paper	Writing - Original Draft	YES
5770196	29416200	AI	1	Revising it critically for intellectual content|Approved final version of the manuscript	Revising it critically for intellectual content	Wrote the paper	Writing - Review & Editing	YES
5770196	29416200	AI	1	Revising it critically for intellectual content|Approved final version of the manuscript	Approved final version of the manuscript	-	-	NO
5770196	29416200	AK	1	Conception and design	Conception and design	Conceived and designed the experiments	Conceptualization	YES
5770196	29416200	AR	1	Acquisition, analysis and interpretation of data	Acquisition, analysis and interpretation of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5770196	29416200	FZ	1	Acquisition, analysis and interpretation of data|Revising it critically for intellectual content	Acquisition, analysis and interpretation of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5770196	29416200	FZ	1	Acquisition, analysis and interpretation of data|Revising it critically for intellectual content	Revising it critically for intellectual content	Wrote the paper	Writing - Review & Editing	YES
5770196	29416200	IT	1	Approved final version of the manuscript	Approved final version of the manuscript	-	-	NO
5770196	29416200	SJ	1	Drafting the article|Revising it critically for intellectual content	Drafting the article	Wrote the paper	Writing - Original Draft	YES
5770196	29416200	SJ	1	Drafting the article|Revising it critically for intellectual content	Revising it critically for intellectual content	Wrote the paper	Writing - Review & Editing	YES
5770196	29416200	SR	1	Acquisition, analysis and interpretation of data	Acquisition, analysis and interpretation of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4951538	27435715	CB	PLoS52	conceived and designed the study|wrote the manuscript|revised the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4951538	27435715	CB	PLoS52	conceived and designed the study|wrote the manuscript|revised the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4951538	27435715	CB	PLoS52	conceived and designed the study|wrote the manuscript|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4951538	27435715	FLA	PLoS52	conceived and designed the study|conceptualized the manuscript|wrote the manuscript|revised the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4951538	27435715	FLA	PLoS52	conceived and designed the study|conceptualized the manuscript|wrote the manuscript|revised the manuscript	conceptualized the manuscript	Conceived and designed the experiments	Conceptualization	YES
4951538	27435715	FLA	PLoS52	conceived and designed the study|conceptualized the manuscript|wrote the manuscript|revised the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4951538	27435715	FLA	PLoS52	conceived and designed the study|conceptualized the manuscript|wrote the manuscript|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4951538	27435715	JAW	PLoS52	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4951538	27435715	JMI	PLoS52	conceived and designed the study|wrote the manuscript|revised the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4951538	27435715	JMI	PLoS52	conceived and designed the study|wrote the manuscript|revised the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4951538	27435715	JMI	PLoS52	conceived and designed the study|wrote the manuscript|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4951538	27435715	LA	PLoS52	conceived and designed the study|performed the experiments|conceptualized the manuscript|analyzed the data|wrote the manuscript|revised the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4951538	27435715	LA	PLoS52	conceived and designed the study|performed the experiments|conceptualized the manuscript|analyzed the data|wrote the manuscript|revised the manuscript	performed the experiments	Performed the experiments	Investigation	YES
4951538	27435715	LA	PLoS52	conceived and designed the study|performed the experiments|conceptualized the manuscript|analyzed the data|wrote the manuscript|revised the manuscript	conceptualized the manuscript	Conceived and designed the experiments	Conceptualization	YES
4951538	27435715	LA	PLoS52	conceived and designed the study|performed the experiments|conceptualized the manuscript|analyzed the data|wrote the manuscript|revised the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
4951538	27435715	LA	PLoS52	conceived and designed the study|performed the experiments|conceptualized the manuscript|analyzed the data|wrote the manuscript|revised the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4951538	27435715	LA	PLoS52	conceived and designed the study|performed the experiments|conceptualized the manuscript|analyzed the data|wrote the manuscript|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4951538	27435715	MP	PLoS52	conceptualized the manuscript|analyzed the data|wrote the manuscript|revised the manuscript	conceptualized the manuscript	Conceived and designed the experiments	Conceptualization	YES
4951538	27435715	MP	PLoS52	conceptualized the manuscript|analyzed the data|wrote the manuscript|revised the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
4951538	27435715	MP	PLoS52	conceptualized the manuscript|analyzed the data|wrote the manuscript|revised the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4951538	27435715	MP	PLoS52	conceptualized the manuscript|analyzed the data|wrote the manuscript|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4951538	27435715	MPW	PLoS52	conceptualized the manuscript|analyzed the data|wrote the manuscript|revised the manuscript	conceptualized the manuscript	Conceived and designed the experiments	Conceptualization	YES
4951538	27435715	MPW	PLoS52	conceptualized the manuscript|analyzed the data|wrote the manuscript|revised the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
4951538	27435715	MPW	PLoS52	conceptualized the manuscript|analyzed the data|wrote the manuscript|revised the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4951538	27435715	MPW	PLoS52	conceptualized the manuscript|analyzed the data|wrote the manuscript|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4951538	27435715	SD	PLoS52	conceived and designed the study|performed the experiments	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4951538	27435715	SD	PLoS52	conceived and designed the study|performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5558093	28855909	DBA	2	contributed in the hplc analysis	contributed in the hplc analysis	Performed the experiments	Investigation	YES
5558093	28855909	IB	2	contributed to the in vitro and the in vivo experiments	contributed to the in vitro and the in vivo experiments	Performed the experiments	Investigation	YES
5558093	28855909	OFG	2	designated the study, performed experimental work and statistical analysis, and wrote the manuscript	designated the study, performed experimental work and statistical analysis, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5558093	28855909	ST	2	critically read and approved the final version of the manuscript and participated in the study design	critically read and approved the final version of the manuscript and participated in the study design	Conceived and designed the experiments	Methodology	YES
5310286	28198679	FZ	2	developed the methods, performed the statistical analysis, and helped to draft the manuscript	developed the methods, performed the statistical analysis, and helped to draft the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5310286	28198679	NHL	2	helped to draft the manuscript	helped to draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5310286	28198679	RM	2	helped to draft the manuscript	helped to draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5310286	28198679	TAM	2	helped to draft the manuscript	helped to draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5310286	28198679	TKN	2	helped to draft the manuscript	helped to draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5310286	28198679	YL	2	conceived of the study, developed the methods, performed the statistical analysis, and drafted the manuscript	conceived of the study, developed the methods, performed the statistical analysis, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
6164889	29973518	Each author	2	contributed to study design, data collection and data analysis	contributed to study design, data collection and data analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Methodology|Resources	YES
5633340	29021897	A Hussain	7	Conception, design, data collection, writing	Conception, design, data collection, writing	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation	YES
5633340	29021897	A Tsiamis	7	Conception, design, supervisory role, revision	Conception, design, supervisory role, revision	Conceived and designed the experiments|Wrote the paper	Conceptualization|Supervision|Writing - Review & Editing	YES
5633340	29021897	C Teng	7	Data collection	Data collection	Performed the experiments	Investigation	YES
5633340	29021897	David Luke	7	Conception, design	Conception, design	Conceived and designed the experiments	Conceptualization	YES
5633340	29021897	F Mahmood	7	data collection, analysis, writing	data collection, analysis, writing	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation	YES
5633340	29021897	S Jafferbhoy	7	design, data collection	design, data collection	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5788507	29416202	AAA	7	Contributed to conception and design|Analysis and interpretation of data|Drafting the article and revising it critically for important intellectual content|Final approval of the version to be published	Contributed to conception and design	Conceived and designed the experiments	Conceptualization	YES
5788507	29416202	AAA	7	Contributed to conception and design|Analysis and interpretation of data|Drafting the article and revising it critically for important intellectual content|Final approval of the version to be published	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
5788507	29416202	AAA	7	Contributed to conception and design|Analysis and interpretation of data|Drafting the article and revising it critically for important intellectual content|Final approval of the version to be published	Drafting the article and revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5788507	29416202	AAA	7	Contributed to conception and design|Analysis and interpretation of data|Drafting the article and revising it critically for important intellectual content|Final approval of the version to be published	Final approval of the version to be published	-	-	NO
5788507	29416202	AKA	7	Contributed to conception and design|Acquisition of data|Final approval of the version to be published	Contributed to conception and design	Conceived and designed the experiments	Conceptualization	YES
5788507	29416202	AKA	7	Contributed to conception and design|Acquisition of data|Final approval of the version to be published	Acquisition of data	Performed the experiments	Investigation	YES
5788507	29416202	AKA	7	Contributed to conception and design|Acquisition of data|Final approval of the version to be published	Final approval of the version to be published	-	-	NO
5788507	29416202	BA	7	Contributed to conception and design|Acquisition of data|Analysis and interpretation of data|Drafting the article and revising it critically for important intellectual content|Final approval of the version to be published	Contributed to conception and design	Conceived and designed the experiments	Conceptualization	YES
5788507	29416202	BA	7	Contributed to conception and design|Acquisition of data|Analysis and interpretation of data|Drafting the article and revising it critically for important intellectual content|Final approval of the version to be published	Acquisition of data	Performed the experiments	Investigation	YES
5788507	29416202	BA	7	Contributed to conception and design|Acquisition of data|Analysis and interpretation of data|Drafting the article and revising it critically for important intellectual content|Final approval of the version to be published	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
5788507	29416202	BA	7	Contributed to conception and design|Acquisition of data|Analysis and interpretation of data|Drafting the article and revising it critically for important intellectual content|Final approval of the version to be published	Drafting the article and revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5788507	29416202	BA	7	Contributed to conception and design|Acquisition of data|Analysis and interpretation of data|Drafting the article and revising it critically for important intellectual content|Final approval of the version to be published	Final approval of the version to be published	-	-	NO
5788507	29416202	IA	7	Contributed to conception and design|Acquisition of data|Drafting the article and revising it critically for important intellectual content|Final approval of the version to be published	Contributed to conception and design	Conceived and designed the experiments	Conceptualization	YES
5788507	29416202	IA	7	Contributed to conception and design|Acquisition of data|Drafting the article and revising it critically for important intellectual content|Final approval of the version to be published	Acquisition of data	Performed the experiments	Investigation	YES
5788507	29416202	IA	7	Contributed to conception and design|Acquisition of data|Drafting the article and revising it critically for important intellectual content|Final approval of the version to be published	Drafting the article and revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5788507	29416202	IA	7	Contributed to conception and design|Acquisition of data|Drafting the article and revising it critically for important intellectual content|Final approval of the version to be published	Final approval of the version to be published	-	-	NO
5788507	29416202	KA	7	Contributed to conception and design|Acquisition of data|Analysis and interpretation of data|Drafting the article and revising it critically for important intellectual content|Final approval of the version to be published	Contributed to conception and design	Conceived and designed the experiments	Conceptualization	YES
5788507	29416202	KA	7	Contributed to conception and design|Acquisition of data|Analysis and interpretation of data|Drafting the article and revising it critically for important intellectual content|Final approval of the version to be published	Acquisition of data	Performed the experiments	Investigation	YES
5788507	29416202	KA	7	Contributed to conception and design|Acquisition of data|Analysis and interpretation of data|Drafting the article and revising it critically for important intellectual content|Final approval of the version to be published	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
5788507	29416202	KA	7	Contributed to conception and design|Acquisition of data|Analysis and interpretation of data|Drafting the article and revising it critically for important intellectual content|Final approval of the version to be published	Drafting the article and revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5788507	29416202	KA	7	Contributed to conception and design|Acquisition of data|Analysis and interpretation of data|Drafting the article and revising it critically for important intellectual content|Final approval of the version to be published	Final approval of the version to be published	-	-	NO
5788507	29416202	TM	7	Contributed to conception and design|Analysis and interpretation of data|Final approval of the version to be published	Contributed to conception and design	Conceived and designed the experiments	Conceptualization	YES
5788507	29416202	TM	7	Contributed to conception and design|Analysis and interpretation of data|Final approval of the version to be published	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
5788507	29416202	TM	7	Contributed to conception and design|Analysis and interpretation of data|Final approval of the version to be published	Final approval of the version to be published	-	-	NO
4406450	25901897	DB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406450	25901897	DB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406450	25901897	DB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406450	25901897	DB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406450	25901897	RB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406450	25901897	RB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406450	25901897	RB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406450	25901897	RB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406450	25901897	RB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406450	25901897	VB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406450	25901897	VB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406450	25901897	VB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406450	25901897	VB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406450	25901897	VB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4951539	27435713	AW	2	contributed to the study concept and design|led the writing and editing of the paper	contributed to the study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4951539	27435713	AW	2	contributed to the study concept and design|led the writing and editing of the paper	led the writing and editing of the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4951539	27435713	MS	2	managed data and statistical analyses|led the writing and editing of the paper	managed data and statistical analyses	Analyzed the data	Data curation|Formal analysis	YES
4951539	27435713	MS	2	managed data and statistical analyses|led the writing and editing of the paper	led the writing and editing of the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5558103	28855912	CD	2	performed most of the experiments	performed most of the experiments	Performed the experiments	Investigation	YES
5558103	28855912	CW	2	provided technical assistance to tl, sd, and nz	provided technical assistance to tl, sd, and nz	Performed the experiments	Investigation	YES
5558103	28855912	GS	2	performed most of the experiments	performed most of the experiments	Performed the experiments	Investigation	YES
5558103	28855912	HZ	2	performed most of the experiments	performed most of the experiments	Performed the experiments	Investigation	YES
5558103	28855912	JX	2	conceived of the original screening and research plans	conceived of the original screening and research plans	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5558103	28855912	JY	2	performed most of the experiments	performed most of the experiments	Performed the experiments	Investigation	YES
5558103	28855912	NZ	2	performed most of the experiments	performed most of the experiments	Performed the experiments	Investigation	YES
5558103	28855912	QD	2	provided technical assistance to tl, sd, and nz	provided technical assistance to tl, sd, and nz	Performed the experiments	Investigation	YES
5558103	28855912	SC	2	conceived of the original screening and research plans|supervised the experiments|supervised and complemented the writing	conceived of the original screening and research plans	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5558103	28855912	SC	2	conceived of the original screening and research plans|supervised the experiments|supervised and complemented the writing	supervised the experiments	-	Supervision	YES
5558103	28855912	SC	2	conceived of the original screening and research plans|supervised the experiments|supervised and complemented the writing	supervised and complemented the writing	Wrote the paper	Supervision	YES
5558103	28855912	SD	2	performed most of the experiments	performed most of the experiments	Performed the experiments	Investigation	YES
5558103	28855912	SL	2	provided technical assistance to tl, sd, and nz	provided technical assistance to tl, sd, and nz	Performed the experiments	Investigation	YES
5558103	28855912	TL	2	conceived of the original screening and research plans|performed most of the experiments|designed the experiments and analyzed the data|conceived of the project and wrote the article, with contributions from all the authors	conceived of the original screening and research plans	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5558103	28855912	TL	2	conceived of the original screening and research plans|performed most of the experiments|designed the experiments and analyzed the data|conceived of the project and wrote the article, with contributions from all the authors	performed most of the experiments	Performed the experiments	Investigation	YES
5558103	28855912	TL	2	conceived of the original screening and research plans|performed most of the experiments|designed the experiments and analyzed the data|conceived of the project and wrote the article, with contributions from all the authors	designed the experiments and analyzed the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5558103	28855912	TL	2	conceived of the original screening and research plans|performed most of the experiments|designed the experiments and analyzed the data|conceived of the project and wrote the article, with contributions from all the authors	conceived of the project and wrote the article, with contributions from all the authors	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5558103	28855912	YW	2	provided technical assistance to tl, sd, and nz	provided technical assistance to tl, sd, and nz	Performed the experiments	Investigation	YES
5558103	28855912	YlZ	2	performed most of the experiments	performed most of the experiments	Performed the experiments	Investigation	YES
5558103	28855912	YnZ	2	performed most of the experiments	performed most of the experiments	Performed the experiments	Investigation	YES
6164923	30018243	H.E.S.	2	contributed to writing of the paper and statistical analyses	contributed to writing of the paper and statistical analyses	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6164923	30018243	J.J.S.	2	led on writing the various drafts of the paper and contributed to the statistical analyses	led on writing the various drafts of the paper and contributed to the statistical analyses	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6164923	30018243	S.K.	2	led on project conceptualization and administration, methodology creation, data collection, data input and statistical analyses and is the primary author of the paper	led on project conceptualization and administration, methodology creation, data collection, data input and statistical analyses and is the primary author of the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Project administration|Writing - Original Draft	YES
4406471	25901736	AS-S	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4406471	25901736	AS-S	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4406471	25901736	AZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406471	25901736	AZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406471	25901736	AZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406471	25901736	CV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406471	25901736	CV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406471	25901736	CV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406471	25901736	CV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406471	25901736	CV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406471	25901736	EC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4406471	25901736	EC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406471	25901736	HM	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4406471	25901736	HM	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4406471	25901736	JAL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406471	25901736	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406471	25901736	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406471	25901736	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406471	25901736	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406471	25901736	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406471	25901736	PV	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406471	25901736	PV	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406471	25901736	PV	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406471	25901736	PV	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406471	25901736	RZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406471	25901736	RZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406471	25901736	RZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406471	25901736	SF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406471	25901736	SF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406471	25901736	SF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406471	25901736	SF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406471	25901736	SN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406471	25901736	SN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406471	25901736	SN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406471	25901736	SN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406471	25901736	SN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406471	25901736	SP	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406471	25901736	SP	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5788508	29416204	Alireza Jalali	2	considered and aimed, the study and drafted the final manuscript and conceived of the study, participated in disseminating and, collecting the survey	considered and aimed, the study and drafted the final manuscript and conceived of the study, participated in disseminating and, collecting the survey	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5788508	29416204	All authors	2	read, and approved of the final manuscript	read, and approved of the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5788508	29416204	Ebrahim Nasiri	2	considered and aimed, the study and drafted the final manuscript and conceived of the study, participated in disseminating and, collecting the survey	considered and aimed, the study and drafted the final manuscript and conceived of the study, participated in disseminating and, collecting the survey	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5788508	29416204	Hasan Siamian	2	translated the article and provided endnote and final modification and submitted the article	translated the article and provided endnote and final modification and submitted the article	Wrote the paper	Writing - Review & Editing	YES
5788508	29416204	Masood Saghafinia	2	considered and aimed, the study and drafted the final manuscript and conceived of the study, participated in disseminating and, collecting the survey	considered and aimed, the study and drafted the final manuscript and conceived of the study, participated in disseminating and, collecting the survey	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5788508	29416204	Mohsen Khoramian	2	considered and aimed, the study and drafted the final manuscript and conceived of the study, participated in disseminating and, collecting the survey	considered and aimed, the study and drafted the final manuscript and conceived of the study, participated in disseminating and, collecting the survey	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5311727	28201983	BW	PLoS52	analyzed the sequence data	analyzed the sequence data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5311727	28201983	GS	PLoS52	conceived and designed the study|revised the paper	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5311727	28201983	GS	PLoS52	conceived and designed the study|revised the paper	revised the paper	Wrote the paper	Writing - Review & Editing	YES
5311727	28201983	MLG	PLoS52	revised the paper	revised the paper	Wrote the paper	Writing - Review & Editing	YES
5311727	28201983	QD	PLoS52	isolated and characterized the fungal isolates	isolated and characterized the fungal isolates	Performed the experiments	Investigation	YES
5311727	28201983	RZ	PLoS52	conceived and designed the study|revised the paper	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5311727	28201983	RZ	PLoS52	conceived and designed the study|revised the paper	revised the paper	Wrote the paper	Writing - Review & Editing	YES
5311727	28201983	TW	PLoS52	isolated and characterized the fungal isolates	isolated and characterized the fungal isolates	Performed the experiments	Investigation	YES
5311727	28201983	WL	PLoS52	isolated and characterized the fungal isolates	isolated and characterized the fungal isolates	Performed the experiments	Investigation	YES
5311727	28201983	WW	PLoS52	isolated and characterized the fungal isolates	isolated and characterized the fungal isolates	Performed the experiments	Investigation	YES
5311727	28201983	XL	PLoS52	conceived and designed the study|analyzed the sequence data|wrote the paper|revised the paper	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5311727	28201983	XL	PLoS52	conceived and designed the study|analyzed the sequence data|wrote the paper|revised the paper	analyzed the sequence data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5311727	28201983	XL	PLoS52	conceived and designed the study|analyzed the sequence data|wrote the paper|revised the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5311727	28201983	XL	PLoS52	conceived and designed the study|analyzed the sequence data|wrote the paper|revised the paper	revised the paper	Wrote the paper	Writing - Review & Editing	YES
5311727	28201983	XT	PLoS52	isolated and characterized the fungal isolates	isolated and characterized the fungal isolates	Performed the experiments	Investigation	YES
5311727	28201983	YM	PLoS52	analyzed the sequence data	analyzed the sequence data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5635338	29034092	FE	PLoS5	Collected data|Interpreted the data	Collected data	Performed the experiments	Investigation	YES
5635338	29034092	FE	PLoS5	Collected data|Interpreted the data	Interpreted the data	Analyzed the data	Formal analysis	YES
5635338	29034092	HK	PLoS5	Collected data	Collected data	Performed the experiments	Investigation	YES
5635338	29034092	HT	PLoS5	Collected data	Collected data	Performed the experiments	Investigation	YES
5635338	29034092	HY	PLoS5	Collected data	Collected data	Performed the experiments	Investigation	YES
5635338	29034092	MA	PLoS5	Collected data	Collected data	Performed the experiments	Investigation	YES
5635338	29034092	MG	PLoS5	Collected data	Collected data	Performed the experiments	Investigation	YES
5635338	29034092	SI	PLoS5	Collected data	Collected data	Performed the experiments	Investigation	YES
5635338	29034092	SN	PLoS5	Collected data	Collected data	Performed the experiments	Investigation	YES
5635338	29034092	SS	PLoS5	Participated in the conception and design of the study|Analyzed the data|Drafted the initial manuscript	Participated in the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5635338	29034092	SS	PLoS5	Participated in the conception and design of the study|Analyzed the data|Drafted the initial manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
5635338	29034092	SS	PLoS5	Participated in the conception and design of the study|Analyzed the data|Drafted the initial manuscript	Drafted the initial manuscript	Wrote the paper	Writing - Original Draft	YES
5635338	29034092	TF	PLoS5	Participated in the conception and design of the study|Analyzed the data|Collected data|Interpreted the data|Drafted the initial manuscript	Participated in the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5635338	29034092	TF	PLoS5	Participated in the conception and design of the study|Analyzed the data|Collected data|Interpreted the data|Drafted the initial manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
5635338	29034092	TF	PLoS5	Participated in the conception and design of the study|Analyzed the data|Collected data|Interpreted the data|Drafted the initial manuscript	Collected data	Performed the experiments	Investigation	YES
5635338	29034092	TF	PLoS5	Participated in the conception and design of the study|Analyzed the data|Collected data|Interpreted the data|Drafted the initial manuscript	Interpreted the data	Analyzed the data	Formal analysis	YES
5635338	29034092	TF	PLoS5	Participated in the conception and design of the study|Analyzed the data|Collected data|Interpreted the data|Drafted the initial manuscript	Drafted the initial manuscript	Wrote the paper	Writing - Original Draft	YES
5635338	29034092	TH	PLoS5	Interpreted the data	Interpreted the data	Analyzed the data	Formal analysis	YES
5635338	29034092	YT	PLoS5	Collected data	Collected data	Performed the experiments	Investigation	YES
4951540	27435707	AL	2	designed the present study|drafted the first manuscript and incorporated suggestions from all co-authors	designed the present study	Conceived and designed the experiments	Methodology	YES
4951540	27435707	AL	2	designed the present study|drafted the first manuscript and incorporated suggestions from all co-authors	drafted the first manuscript and incorporated suggestions from all co-authors	Wrote the paper	Writing - Original Draft	YES
4951540	27435707	All authors	2	made significant contributions to the conception of the analyses, interpretation of the data and drafting of the manuscript	made significant contributions to the conception of the analyses, interpretation of the data and drafting of the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Resources|Writing - Original Draft	YES
4951540	27435707	EW	2	designed and managed the cohort studies that the present study was drawn from	designed and managed the cohort studies that the present study was drawn from	Conceived and designed the experiments	Methodology|Project administration	YES
4951540	27435707	HD	2	conducted the statistical analyses	conducted the statistical analyses	Analyzed the data	Formal analysis	YES
4951540	27435707	KH	2	designed and managed the cohort studies that the present study was drawn from|designed the present study	designed and managed the cohort studies that the present study was drawn from	Conceived and designed the experiments	Methodology|Project administration	YES
4951540	27435707	KH	2	designed and managed the cohort studies that the present study was drawn from|designed the present study	designed the present study	Conceived and designed the experiments	Methodology	YES
4951540	27435707	MJM	2	designed and managed the cohort studies that the present study was drawn from	designed and managed the cohort studies that the present study was drawn from	Conceived and designed the experiments	Methodology|Project administration	YES
4951540	27435707	PN	2	conducted the statistical analyses	conducted the statistical analyses	Analyzed the data	Formal analysis	YES
4951540	27435707	TK	2	designed and managed the cohort studies that the present study was drawn from	designed and managed the cohort studies that the present study was drawn from	Conceived and designed the experiments	Methodology|Project administration	YES
3549366	23346406	D. R. Woode	2	contributed equally to this work|was responsible for performing the experimental procedures, analysis of data, and writing the paper	contributed equally to this work	-	-	NO
3549366	23346406	D. R. Woode	2	contributed equally to this work|was responsible for performing the experimental procedures, analysis of data, and writing the paper	was responsible for performing the experimental procedures, analysis of data, and writing the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3549366	23346406	H. S. Aiyer	2	contributed equally to this work|was responsible for the original idea, overall planning and supervision of the study, analysis of data, and writing and editing the paper	contributed equally to this work	-	-	NO
3549366	23346406	H. S. Aiyer	2	contributed equally to this work|was responsible for the original idea, overall planning and supervision of the study, analysis of data, and writing and editing the paper	was responsible for the original idea, overall planning and supervision of the study, analysis of data, and writing and editing the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
5558127	28855911	AZ	2	conducted the experiments and data analysis|wrote and/or edited the manuscript	conducted the experiments and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5558127	28855911	AZ	2	conducted the experiments and data analysis|wrote and/or edited the manuscript	wrote and/or edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5558127	28855911	BS	2	conceived and supervised the project|wrote and/or edited the manuscript	conceived and supervised the project	Conceived and designed the experiments	Conceptualization|Supervision	YES
5558127	28855911	BS	2	conceived and supervised the project|wrote and/or edited the manuscript	wrote and/or edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5558127	28855911	CB	2	conducted the experiments and data analysis|wrote and/or edited the manuscript	conducted the experiments and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5558127	28855911	CB	2	conducted the experiments and data analysis|wrote and/or edited the manuscript	wrote and/or edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5558127	28855911	GB	2	discussed the project|wrote and/or edited the manuscript	discussed the project	-	-	NO
5558127	28855911	GB	2	discussed the project|wrote and/or edited the manuscript	wrote and/or edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5558127	28855911	GC	2	conducted the experiments and data analysis	conducted the experiments and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5558127	28855911	JD	2	discussed the project	discussed the project	-	-	NO
5558127	28855911	JS	2	prepared and identified the arabidopsis glyr1 overexpression lines	prepared and identified the arabidopsis glyr1 overexpression lines	Performed the experiments	Investigation	YES
5558127	28855911	VB	2	conducted the experiments and data analysis	conducted the experiments and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5643079	29062477	Gaurav Parashar	7	Concept, design, definition of intellectual content, literature search, data acquisition, manuscript editing and manuscript review. 4	Concept, design, definition of intellectual content, literature search, data acquisition, manuscript editing and manuscript review. 4	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Review & Editing	YES
5643079	29062477	Rachit Goel	7	Concept, design, definition of intellectual content, literature search, data acquisition, manuscript editing and manuscript review. 3	Concept, design, definition of intellectual content, literature search, data acquisition, manuscript editing and manuscript review. 3	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Review & Editing	YES
5643079	29062477	Ramesh Santhanakrishnan	7	Concept, design, definition of intellectual content, literature search, data acquisition, manuscript editing and manuscript review	Concept, design, definition of intellectual content, literature search, data acquisition, manuscript editing and manuscript review	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Review & Editing	YES
5643079	29062477	Veerabhadra Radhakrishna	7	Concept, design, definition of intellectual content, literature search, data acquisition, manuscript preparation, manuscript editing and manuscript review. 2	Concept, design, definition of intellectual content, literature search, data acquisition, manuscript preparation, manuscript editing and manuscript review. 2	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
4406474	25902315	CB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406474	25902315	CB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406474	25902315	CB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406474	25902315	DAB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406474	25902315	DAB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406474	25902315	DAB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406474	25902315	DAB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406474	25902315	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406474	25902315	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406474	25902315	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406474	25902315	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406474	25902315	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406474	25902315	WB	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406474	25902315	WB	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5644998	29062478	Ernest Chew	7	Study design, analysis, manuscript writing|Study design, analysis, manuscript writing	Study design, analysis, manuscript writing	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5644998	29062478	Ernest Chew	7	Study design, analysis, manuscript writing|Study design, analysis, manuscript writing	Study design, analysis, manuscript writing	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5644998	29062478	Rohan Prakash	7	Study design, analysis, manuscript writing	Study design, analysis, manuscript writing	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5644998	29062478	Wasim Khan	7	Study design, manuscript editing	Study design, manuscript editing	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5788509	29416203	Kaveh B. Kelarestaghi	2	recommended the statistical models and performed the correlation and regression analyses	recommended the statistical models and performed the correlation and regression analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
6165087	30041428	D.Y.	CRediT	Conceptualization|Investigation|Validation|Writing--Original draft	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6165087	30041428	D.Y.	CRediT	Conceptualization|Investigation|Validation|Writing--Original draft	Investigation	Performed the experiments	Investigation	YES
6165087	30041428	D.Y.	CRediT	Conceptualization|Investigation|Validation|Writing--Original draft	Validation	Performed the experiments	Validation	YES
6165087	30041428	D.Y.	CRediT	Conceptualization|Investigation|Validation|Writing--Original draft	Writing--Original draft	Wrote the paper	Writing - Original Draft	YES
6165087	30041428	L.C.-A.	CRediT	Conceptualization|Funding acquisition|Supervision|Validation|Writing--Original draft|Writing--Review and editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6165087	30041428	L.C.-A.	CRediT	Conceptualization|Funding acquisition|Supervision|Validation|Writing--Original draft|Writing--Review and editing	Funding acquisition	-	Funding acquisition	YES
6165087	30041428	L.C.-A.	CRediT	Conceptualization|Funding acquisition|Supervision|Validation|Writing--Original draft|Writing--Review and editing	Supervision	-	Supervision	YES
6165087	30041428	L.C.-A.	CRediT	Conceptualization|Funding acquisition|Supervision|Validation|Writing--Original draft|Writing--Review and editing	Validation	Performed the experiments	Validation	YES
6165087	30041428	L.C.-A.	CRediT	Conceptualization|Funding acquisition|Supervision|Validation|Writing--Original draft|Writing--Review and editing	Writing--Original draft	Wrote the paper	Writing - Original Draft	YES
6165087	30041428	L.C.-A.	CRediT	Conceptualization|Funding acquisition|Supervision|Validation|Writing--Original draft|Writing--Review and editing	Writing--Review and editing	Wrote the paper	Writing - Review & Editing	YES
6165087	30041428	L.C.D.	CRediT	Formal analysis|Validation|Writing--Original draft|Writing--Review and editing	Formal analysis	Analyzed the data	Formal analysis	YES
6165087	30041428	L.C.D.	CRediT	Formal analysis|Validation|Writing--Original draft|Writing--Review and editing	Validation	Performed the experiments	Validation	YES
6165087	30041428	L.C.D.	CRediT	Formal analysis|Validation|Writing--Original draft|Writing--Review and editing	Writing--Original draft	Wrote the paper	Writing - Original Draft	YES
6165087	30041428	L.C.D.	CRediT	Formal analysis|Validation|Writing--Original draft|Writing--Review and editing	Writing--Review and editing	Wrote the paper	Writing - Review & Editing	YES
6165087	30041428	L.S.N.	CRediT	Validation|Writing--Original draft|Writing--Review and editing	Validation	Performed the experiments	Validation	YES
6165087	30041428	L.S.N.	CRediT	Validation|Writing--Original draft|Writing--Review and editing	Writing--Original draft	Wrote the paper	Writing - Original Draft	YES
6165087	30041428	L.S.N.	CRediT	Validation|Writing--Original draft|Writing--Review and editing	Writing--Review and editing	Wrote the paper	Writing - Review & Editing	YES
6165087	30041428	M.K.	CRediT	Validation|Writing--Original draft|Writing--Review and editing	Validation	Performed the experiments	Validation	YES
6165087	30041428	M.K.	CRediT	Validation|Writing--Original draft|Writing--Review and editing	Writing--Original draft	Wrote the paper	Writing - Original Draft	YES
6165087	30041428	M.K.	CRediT	Validation|Writing--Original draft|Writing--Review and editing	Writing--Review and editing	Wrote the paper	Writing - Review & Editing	YES
5312515	28209126	JN	PLoS5	Conceived and designed the experiments|Performed the meta-analysis|Analyzed the data|Wrote the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5312515	28209126	JN	PLoS5	Conceived and designed the experiments|Performed the meta-analysis|Analyzed the data|Wrote the manuscript	Performed the meta-analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5312515	28209126	JN	PLoS5	Conceived and designed the experiments|Performed the meta-analysis|Analyzed the data|Wrote the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
5312515	28209126	JN	PLoS5	Conceived and designed the experiments|Performed the meta-analysis|Analyzed the data|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5312515	28209126	MS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5312515	28209126	MS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
5312515	28209126	MS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5312515	28209126	NV	PLoS5	Analyzed the data|Wrote the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
5312515	28209126	NV	PLoS5	Analyzed the data|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4951541	27435716	BS	2	also drafted sections of the article	also drafted sections of the article	Wrote the paper	Writing - Original Draft	YES
4951541	27435716	KF	2	conceptualized the study, led the systematic review process and full text reviews and wrote the article	conceptualized the study, led the systematic review process and full text reviews and wrote the article	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
4951541	27435716	SS	2	assisted with development of the search protocol and provided critical review of this article	assisted with development of the search protocol and provided critical review of this article	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5558542	28855913	LZ	PLoS52	conceived the experiments|contributed materials, reagents, and analysis tools|wrote the paper	conceived the experiments	Conceived and designed the experiments	Conceptualization	YES
5558542	28855913	LZ	PLoS52	conceived the experiments|contributed materials, reagents, and analysis tools|wrote the paper	contributed materials, reagents, and analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5558542	28855913	LZ	PLoS52	conceived the experiments|contributed materials, reagents, and analysis tools|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5558542	28855913	QH	PLoS52	participated in the analysis of genes expression	participated in the analysis of genes expression	Performed the experiments	Investigation	YES
5558542	28855913	XM	PLoS52	participated in collecting seeds	participated in collecting seeds	-	-	NO
5558542	28855913	YR	PLoS52	conceived the experiments|performed the experiments|wrote the paper	conceived the experiments	Conceived and designed the experiments	Conceptualization	YES
5558542	28855913	YR	PLoS52	conceived the experiments|performed the experiments|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5558542	28855913	YR	PLoS52	conceived the experiments|performed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4495182	26199943	Yue Feng	2	contributed equally to this work	contributed equally to this work	-	-	NO
4495182	26199943	Yue Zhao	2	contributed equally to this work	contributed equally to this work	-	-	NO
5645003	29062480	All authors	2	in this manuscript contributed to the interpretation of data, and drafting and writing of this manuscript	in this manuscript contributed to the interpretation of data, and drafting and writing of this manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
5645003	29062480	Kazuto Hoshi	2	were engaged in patients care in our hospital including surgery	were engaged in patients care in our hospital including surgery	Performed the experiments	Investigation	YES
5645003	29062480	Kosuke Kanke	2	is first author of this paper|conceived and designed the study and drafted the manuscript|were engaged in patients care in our hospital including surgery	is first author of this paper	-	-	NO
5645003	29062480	Kosuke Kanke	2	is first author of this paper|conceived and designed the study and drafted the manuscript|were engaged in patients care in our hospital including surgery	conceived and designed the study and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
5645003	29062480	Kosuke Kanke	2	is first author of this paper|conceived and designed the study and drafted the manuscript|were engaged in patients care in our hospital including surgery	were engaged in patients care in our hospital including surgery	Performed the experiments	Investigation	YES
5645003	29062480	Masanobu Abe	2	were engaged in patients care in our hospital including surgery	were engaged in patients care in our hospital including surgery	Performed the experiments	Investigation	YES
5645003	29062480	Takahiro Abe	2	is corresponding author of this paper|conceived and designed the study and drafted the manuscript|were engaged in patients care in our hospital including surgery	is corresponding author of this paper	-	-	NO
5645003	29062480	Takahiro Abe	2	is corresponding author of this paper|conceived and designed the study and drafted the manuscript|were engaged in patients care in our hospital including surgery	conceived and designed the study and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
5645003	29062480	Takahiro Abe	2	is corresponding author of this paper|conceived and designed the study and drafted the manuscript|were engaged in patients care in our hospital including surgery	were engaged in patients care in our hospital including surgery	Performed the experiments	Investigation	YES
5645003	29062480	Tsuyoshi Takato	2	were engaged in patients care in our hospital including surgery	were engaged in patients care in our hospital including surgery	Performed the experiments	Investigation	YES
5645003	29062480	Yoshiyuki Mori	2	were engaged in patients care in our hospital including surgery	were engaged in patients care in our hospital including surgery	Performed the experiments	Investigation	YES
3324131	22550568	A. G. Marcelin	2	discussed the results and improved the paper	discussed the results and improved the paper	Wrote the paper	Writing - Review & Editing	YES
3324131	22550568	A. Houssaini	2	designed research|performed analysis|discussed the results and improved the paper	designed research	Conceived and designed the experiments	Methodology	YES
3324131	22550568	A. Houssaini	2	designed research|performed analysis|discussed the results and improved the paper	performed analysis	Performed the experiments	Investigation	YES
3324131	22550568	A. Houssaini	2	designed research|performed analysis|discussed the results and improved the paper	discussed the results and improved the paper	Wrote the paper	Writing - Review & Editing	YES
3324131	22550568	J. M. Molina	2	discussed the results and improved the paper	discussed the results and improved the paper	Wrote the paper	Writing - Review & Editing	YES
3324131	22550568	L. Assoumou	2	discussed the results and improved the paper	discussed the results and improved the paper	Wrote the paper	Writing - Review & Editing	YES
3324131	22550568	P. Flandre	2	designed research|performed analysis|discussed the results and improved the paper	designed research	Conceived and designed the experiments	Methodology	YES
3324131	22550568	P. Flandre	2	designed research|performed analysis|discussed the results and improved the paper	performed analysis	Performed the experiments	Investigation	YES
3324131	22550568	P. Flandre	2	designed research|performed analysis|discussed the results and improved the paper	discussed the results and improved the paper	Wrote the paper	Writing - Review & Editing	YES
3324131	22550568	V. Calvez	2	discussed the results and improved the paper	discussed the results and improved the paper	Wrote the paper	Writing - Review & Editing	YES
4406477	25902012	DCS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406477	25902012	DCS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406477	25902012	DCS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406477	25902012	DCS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406477	25902012	DCS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406477	25902012	ERW	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406477	25902012	ERW	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406477	25902012	ERW	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406477	25902012	ERW	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406477	25902012	JJK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406477	25902012	JJK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406477	25902012	JJK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406477	25902012	JvdO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406477	25902012	JvdO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406477	25902012	JvdO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406477	25902012	JvdO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406477	25902012	PJS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406477	25902012	PJS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406477	25902012	PJS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6165107	30104554	A.A.	CRediT	Conceptualization|Methodology|Validation|Formal analysis|Resources|Writing-review & editing|Visualization|Supervision	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6165107	30104554	A.A.	CRediT	Conceptualization|Methodology|Validation|Formal analysis|Resources|Writing-review & editing|Visualization|Supervision	Methodology	Performed the experiments	Methodology	YES
6165107	30104554	A.A.	CRediT	Conceptualization|Methodology|Validation|Formal analysis|Resources|Writing-review & editing|Visualization|Supervision	Validation	Performed the experiments	Validation	YES
6165107	30104554	A.A.	CRediT	Conceptualization|Methodology|Validation|Formal analysis|Resources|Writing-review & editing|Visualization|Supervision	Formal analysis	Analyzed the data	Formal analysis	YES
6165107	30104554	A.A.	CRediT	Conceptualization|Methodology|Validation|Formal analysis|Resources|Writing-review & editing|Visualization|Supervision	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6165107	30104554	A.A.	CRediT	Conceptualization|Methodology|Validation|Formal analysis|Resources|Writing-review & editing|Visualization|Supervision	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6165107	30104554	A.A.	CRediT	Conceptualization|Methodology|Validation|Formal analysis|Resources|Writing-review & editing|Visualization|Supervision	Visualization	Analyzed the data	Visualization	YES
6165107	30104554	A.A.	CRediT	Conceptualization|Methodology|Validation|Formal analysis|Resources|Writing-review & editing|Visualization|Supervision	Supervision	-	Supervision	YES
6165107	30104554	A.Z.	CRediT	Conceptualization|Methodology|Software|Formal analysis|Investigation|Data curation|Writing-original draft preparation|Visualization	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6165107	30104554	A.Z.	CRediT	Conceptualization|Methodology|Software|Formal analysis|Investigation|Data curation|Writing-original draft preparation|Visualization	Methodology	Performed the experiments	Methodology	YES
6165107	30104554	A.Z.	CRediT	Conceptualization|Methodology|Software|Formal analysis|Investigation|Data curation|Writing-original draft preparation|Visualization	Software	Contributed reagents/materials/analysis tools	Software	YES
6165107	30104554	A.Z.	CRediT	Conceptualization|Methodology|Software|Formal analysis|Investigation|Data curation|Writing-original draft preparation|Visualization	Formal analysis	Analyzed the data	Formal analysis	YES
6165107	30104554	A.Z.	CRediT	Conceptualization|Methodology|Software|Formal analysis|Investigation|Data curation|Writing-original draft preparation|Visualization	Investigation	Performed the experiments	Investigation	YES
6165107	30104554	A.Z.	CRediT	Conceptualization|Methodology|Software|Formal analysis|Investigation|Data curation|Writing-original draft preparation|Visualization	Data curation	Analyzed the data	Data curation	YES
6165107	30104554	A.Z.	CRediT	Conceptualization|Methodology|Software|Formal analysis|Investigation|Data curation|Writing-original draft preparation|Visualization	Writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
6165107	30104554	A.Z.	CRediT	Conceptualization|Methodology|Software|Formal analysis|Investigation|Data curation|Writing-original draft preparation|Visualization	Visualization	Analyzed the data	Visualization	YES
6165107	30104554	D.C.R.F.	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
6165107	30104554	M.E.-H.	CRediT	Validation|Resources|Writing-review & editing|Visualization|Supervision	Validation	Performed the experiments	Validation	YES
6165107	30104554	M.E.-H.	CRediT	Validation|Resources|Writing-review & editing|Visualization|Supervision	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6165107	30104554	M.E.-H.	CRediT	Validation|Resources|Writing-review & editing|Visualization|Supervision	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6165107	30104554	M.E.-H.	CRediT	Validation|Resources|Writing-review & editing|Visualization|Supervision	Visualization	Analyzed the data	Visualization	YES
6165107	30104554	M.E.-H.	CRediT	Validation|Resources|Writing-review & editing|Visualization|Supervision	Supervision	-	Supervision	YES
6165107	30104554	N.K.	CRediT	Conceptualization|Methodology|Validation|Formal analysis|Resources|Writing-review & editing|Visualization|Supervision|Project administration|Funding acquisition	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6165107	30104554	N.K.	CRediT	Conceptualization|Methodology|Validation|Formal analysis|Resources|Writing-review & editing|Visualization|Supervision|Project administration|Funding acquisition	Methodology	Performed the experiments	Methodology	YES
6165107	30104554	N.K.	CRediT	Conceptualization|Methodology|Validation|Formal analysis|Resources|Writing-review & editing|Visualization|Supervision|Project administration|Funding acquisition	Validation	Performed the experiments	Validation	YES
6165107	30104554	N.K.	CRediT	Conceptualization|Methodology|Validation|Formal analysis|Resources|Writing-review & editing|Visualization|Supervision|Project administration|Funding acquisition	Formal analysis	Analyzed the data	Formal analysis	YES
6165107	30104554	N.K.	CRediT	Conceptualization|Methodology|Validation|Formal analysis|Resources|Writing-review & editing|Visualization|Supervision|Project administration|Funding acquisition	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6165107	30104554	N.K.	CRediT	Conceptualization|Methodology|Validation|Formal analysis|Resources|Writing-review & editing|Visualization|Supervision|Project administration|Funding acquisition	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6165107	30104554	N.K.	CRediT	Conceptualization|Methodology|Validation|Formal analysis|Resources|Writing-review & editing|Visualization|Supervision|Project administration|Funding acquisition	Visualization	Analyzed the data	Visualization	YES
6165107	30104554	N.K.	CRediT	Conceptualization|Methodology|Validation|Formal analysis|Resources|Writing-review & editing|Visualization|Supervision|Project administration|Funding acquisition	Supervision	-	Supervision	YES
6165107	30104554	N.K.	CRediT	Conceptualization|Methodology|Validation|Formal analysis|Resources|Writing-review & editing|Visualization|Supervision|Project administration|Funding acquisition	Project administration	-	Project administration	YES
6165107	30104554	N.K.	CRediT	Conceptualization|Methodology|Validation|Formal analysis|Resources|Writing-review & editing|Visualization|Supervision|Project administration|Funding acquisition	Funding acquisition	-	Funding acquisition	YES
6165107	30104554	S.A.A.A.	CRediT	Resources|Writing-review & editing	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6165107	30104554	S.A.A.A.	CRediT	Resources|Writing-review & editing	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
5559465	28861091	PL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5559465	28861091	PL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
5559465	28861091	PL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5559465	28861091	PL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5559465	28861091	Q-LD	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5559465	28861091	Q-LD	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5559465	28861091	RM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5559465	28861091	RM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
5559465	28861091	RM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5559465	28861091	RM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4951542	27435712	AR	2	contributed with important intellectual inputs	contributed with important intellectual inputs	-	-	NO
4951542	27435712	All authors	2	contributed to the design of the study|provided feedback on drafts and approved its final version	contributed to the design of the study	Conceived and designed the experiments	Methodology	YES
4951542	27435712	All authors	2	contributed to the design of the study|provided feedback on drafts and approved its final version	provided feedback on drafts and approved its final version	Wrote the paper	Writing - Original Draft	YES
4951542	27435712	EB	2	oversaw data collection and management	oversaw data collection and management	Performed the experiments	Investigation|Supervision	YES
4951542	27435712	EK	2	oversaw data collection and management	oversaw data collection and management	Performed the experiments	Investigation|Supervision	YES
4951542	27435712	EQ	2	conducted the analysis	conducted the analysis	Performed the experiments	Investigation	YES
4951542	27435712	JL	2	contributed with important intellectual inputs	contributed with important intellectual inputs	-	-	NO
4951542	27435712	JS	2	contributed with important intellectual inputs	contributed with important intellectual inputs	-	-	NO
4951542	27435712	KL	2	drafted the article|had full access to all the data in the study and had final responsibility for the decision to submit the study for publication	drafted the article	Wrote the paper	Writing - Original Draft	YES
4951542	27435712	KL	2	drafted the article|had full access to all the data in the study and had final responsibility for the decision to submit the study for publication	had full access to all the data in the study and had final responsibility for the decision to submit the study for publication	-	-	NO
5312533	28209119	DZ	2	helped to perform the experiment and contributed the sequence data	helped to perform the experiment and contributed the sequence data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5312533	28209119	GH	2	contributed plant material	contributed plant material	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5312533	28209119	IAA	2	helped to improve the manuscript significantly	helped to improve the manuscript significantly	Wrote the paper	Writing - Review & Editing	YES
5312533	28209119	JL	2	conceived the study and drafted the manuscript	conceived the study and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5312533	28209119	KM	2	helped to analyze the data|contributed to the discussion of study design	helped to analyze the data	Analyzed the data	Formal analysis	YES
5312533	28209119	KM	2	helped to analyze the data|contributed to the discussion of study design	contributed to the discussion of study design	Conceived and designed the experiments	Methodology	YES
5312533	28209119	LZ	2	contributed plant material	contributed plant material	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5312533	28209119	MAK	2	helped to improve the manuscript significantly	helped to improve the manuscript significantly	Wrote the paper	Writing - Review & Editing	YES
5312533	28209119	QH	2	contributed to the discussion of study design	contributed to the discussion of study design	Conceived and designed the experiments	Methodology	YES
5312533	28209119	TM	2	contributed to the discussion of study design	contributed to the discussion of study design	Conceived and designed the experiments	Methodology	YES
5312533	28209119	XG	2	conceived the study and drafted the manuscript|performed the experiment, analyzed the data and interpreted the results	conceived the study and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5312533	28209119	XG	2	conceived the study and drafted the manuscript|performed the experiment, analyzed the data and interpreted the results	performed the experiment, analyzed the data and interpreted the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5312533	28209119	XW	2	helped to analyze the data	helped to analyze the data	Analyzed the data	Formal analysis	YES
5645008	29062479	All authors	2	gave feedback to the manuscript and approved of its final form	gave feedback to the manuscript and approved of its final form	-	-	NO
5645008	29062479	Karoline Sander	2	conducted the experiments and performed the stains	conducted the experiments and performed the stains	Performed the experiments	Investigation	YES
5645008	29062479	Sabine Richter	2	conducted the experiments and performed the stains	conducted the experiments and performed the stains	Performed the experiments	Investigation	YES
5645008	29062479	Uwe Wittel	2	established the experimental models, formulated the driving hypothesis, and supervised the study|drafted and completed the manuscript	established the experimental models, formulated the driving hypothesis, and supervised the study	Conceived and designed the experiments|Performed the experiments	Conceptualization|Methodology|Supervision	YES
5645008	29062479	Uwe Wittel	2	established the experimental models, formulated the driving hypothesis, and supervised the study|drafted and completed the manuscript	drafted and completed the manuscript	Wrote the paper	Writing - Original Draft	YES
4406491	25901576	BM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406491	25901576	BM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406491	25901576	BM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406491	25901576	BM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406491	25901576	BM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406491	25901576	CH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406491	25901576	CH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406491	25901576	CH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406491	25901576	CH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406491	25901576	DR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406491	25901576	DR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406491	25901576	DR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406491	25901576	DS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406491	25901576	DS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4406491	25901576	DS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406491	25901576	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406491	25901576	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406491	25901576	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406491	25901576	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406491	25901576	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406491	25901576	SR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406491	25901576	SR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4406491	25901576	SR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4406491	25901576	SR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5788512	29416201	All authors	2	participated in every step of research and gave final approval of the version to be submitted	participated in every step of research and gave final approval of the version to be submitted	-	-	NO
5647468	29062482	Shahidatul-Adha Mohamad	7	study design, data collection, data analysis and writing paper	study design, data collection, data analysis and writing paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5647468	29062482	Zunaina Embong	7	study design, data analysis, writing paper. Liza Sharmini AT, Wan Hazabbah WH, Shatriah I, Mohtar I, Azhany Y, Adil H - data analysis and discussion	study design, data analysis, writing paper. Liza Sharmini AT, Wan Hazabbah WH, Shatriah I, Mohtar I, Azhany Y, Adil H - data analysis and discussion	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4956730	27443270	All authors	2	reviewed and approved the final version	reviewed and approved the final version	-	-	NO
4956730	27443270	BZ	2	led the data analysis	led the data analysis	Analyzed the data	Formal analysis	YES
4956730	27443270	JO	2	contributed to part of the introduction	contributed to part of the introduction	-	-	NO
4956730	27443270	LB	2	contributed to table 2	contributed to table 2	-	-	NO
4956730	27443270	LV	2	conceived the study and had overall responsibility for writing the manuscript|led the data analysis	conceived the study and had overall responsibility for writing the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4956730	27443270	LV	2	conceived the study and had overall responsibility for writing the manuscript|led the data analysis	led the data analysis	Analyzed the data	Formal analysis	YES
4956730	27443270	NJ	2	led the larger task-shifting study that provided the costing data for this paper|reviewed the first draft and was responsible for copy-editing	led the larger task-shifting study that provided the costing data for this paper	Contributed reagents/materials/analysis tools	Resources	YES
4956730	27443270	NJ	2	led the larger task-shifting study that provided the costing data for this paper|reviewed the first draft and was responsible for copy-editing	reviewed the first draft and was responsible for copy-editing	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4956730	27443270	SK	2	led the larger task-shifting study that provided the costing data for this paper	led the larger task-shifting study that provided the costing data for this paper	Contributed reagents/materials/analysis tools	Resources	YES
4956730	27443270	SO	2	contributed to table 2	contributed to table 2	-	-	NO
4956730	27443270	SW	2	contributed to table 2|contributed to part of the introduction	contributed to table 2	-	-	NO
4956730	27443270	SW	2	contributed to table 2|contributed to part of the introduction	contributed to part of the introduction	-	-	NO
5559499	28861103	CS	1	Manuscript draft	Manuscript draft	Wrote the paper	Writing - Original Draft	YES
5559499	28861103	FL	1	Manuscript draft	Manuscript draft	Wrote the paper	Writing - Original Draft	YES
5559499	28861103	JZ	1	Experiments	Experiments	-	-	NO
5559499	28861103	LT	1	Manuscript draft	Manuscript draft	Wrote the paper	Writing - Original Draft	YES
5559499	28861103	MC	1	Experiments	Experiments	-	-	NO
5559499	28861103	SW	1	Manuscript draft|Experiments	Manuscript draft	Wrote the paper	Writing - Original Draft	YES
5559499	28861103	SW	1	Manuscript draft|Experiments	Experiments	-	-	NO
5559499	28861103	WC	1	Experiments	Experiments	-	-	NO
5559499	28861103	XM	1	Manuscript draft|Analyzing data	Manuscript draft	Wrote the paper	Writing - Original Draft	YES
5559499	28861103	XM	1	Manuscript draft|Analyzing data	Analyzing data	Analyzed the data	Formal analysis	YES
5312535	28201986	DMI	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5312535	28201986	GDW	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5312535	28201986	GDW	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5312535	28201986	GDW	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5312535	28201986	HCY	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5312535	28201986	HCY	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5312535	28201986	HCY	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5312535	28201986	HCY	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5312535	28201986	HW	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5312535	28201986	LZ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5312535	28201986	MW	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5312535	28201986	RXF	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5312535	28201986	TTY	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5312535	28201986	WZ	PLoS52	conceived and designed the experiments|analyzed the data|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5312535	28201986	WZ	PLoS52	conceived and designed the experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5312535	28201986	WZ	PLoS52	conceived and designed the experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5312535	28201986	YPM	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5312535	28201986	YPZ	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406492	25901354	JWS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406492	25901354	JWS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406492	25901354	JWS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406492	25901354	JWS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406492	25901354	TYC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4406492	25901354	TYC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406492	25901354	WCL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406492	25901354	WCL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406492	25901354	WCL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406492	25901354	WCL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406492	25901354	WTC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
3324885	22548156	All authors	2	approved and read the final paper|participated in critical appraisal of the paper	approved and read the final paper	-	-	NO
3324885	22548156	All authors	2	approved and read the final paper|participated in critical appraisal of the paper	participated in critical appraisal of the paper	-	-	NO
3324885	22548156	F. Odhiambo	2	assisted in the collection of data and technical aspects of the paper|participated in design and helped to draft the paper	assisted in the collection of data and technical aspects of the paper	Performed the experiments	Investigation	YES
3324885	22548156	F. Odhiambo	2	assisted in the collection of data and technical aspects of the paper|participated in design and helped to draft the paper	participated in design and helped to draft the paper	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
3324885	22548156	G. Kiiru	2	assisted in the collection of data and technical aspects of the paper	assisted in the collection of data and technical aspects of the paper	Performed the experiments	Investigation	YES
3324885	22548156	Memiah Conceived	2	designed the study and collected data in the field, performed analysis, interpretation of data, and critical review of the paper	designed the study and collected data in the field, performed analysis, interpretation of data, and critical review of the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Review & Editing	YES
3324885	22548156	P. Memiah	2	participated in design and helped to draft the paper	participated in design and helped to draft the paper	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
3324885	22548156	S. Agbor	2	assisted in the collection of data and technical aspects of the paper	assisted in the collection of data and technical aspects of the paper	Performed the experiments	Investigation	YES
3324885	22548156	S. Biadgilign	2	assisted with the design, interpretation of data, draft, and critical review of the paper	assisted with the design, interpretation of data, draft, and critical review of the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
3324885	22548156	S. Ojoo	2	assisted in the collection of data and technical aspects of the paper	assisted in the collection of data and technical aspects of the paper	Performed the experiments	Investigation	YES
3324885	22548156	W. Mbuthia	2	assisted in the collection of data and technical aspects of the paper|participated in design and helped to draft the paper	assisted in the collection of data and technical aspects of the paper	Performed the experiments	Investigation	YES
3324885	22548156	W. Mbuthia	2	assisted in the collection of data and technical aspects of the paper|participated in design and helped to draft the paper	participated in design and helped to draft the paper	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
6165192	30135400	B.D.G.	CRediT	Writing-review & editing|Supervision|Project administration	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6165192	30135400	B.D.G.	CRediT	Writing-review & editing|Supervision|Project administration	Supervision	-	Supervision	YES
6165192	30135400	B.D.G.	CRediT	Writing-review & editing|Supervision|Project administration	Project administration	-	Project administration	YES
6165192	30135400	I.M.H.	CRediT	Conceptualization|Methodology|Formal analysis|Investigation|Data curation|Writing-original draft preparation|Writing-review & editing|Funding acquisition	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6165192	30135400	I.M.H.	CRediT	Conceptualization|Methodology|Formal analysis|Investigation|Data curation|Writing-original draft preparation|Writing-review & editing|Funding acquisition	Methodology	Performed the experiments	Methodology	YES
6165192	30135400	I.M.H.	CRediT	Conceptualization|Methodology|Formal analysis|Investigation|Data curation|Writing-original draft preparation|Writing-review & editing|Funding acquisition	Formal analysis	Analyzed the data	Formal analysis	YES
6165192	30135400	I.M.H.	CRediT	Conceptualization|Methodology|Formal analysis|Investigation|Data curation|Writing-original draft preparation|Writing-review & editing|Funding acquisition	Investigation	Performed the experiments	Investigation	YES
6165192	30135400	I.M.H.	CRediT	Conceptualization|Methodology|Formal analysis|Investigation|Data curation|Writing-original draft preparation|Writing-review & editing|Funding acquisition	Data curation	Analyzed the data	Data curation	YES
6165192	30135400	I.M.H.	CRediT	Conceptualization|Methodology|Formal analysis|Investigation|Data curation|Writing-original draft preparation|Writing-review & editing|Funding acquisition	Writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
6165192	30135400	I.M.H.	CRediT	Conceptualization|Methodology|Formal analysis|Investigation|Data curation|Writing-original draft preparation|Writing-review & editing|Funding acquisition	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6165192	30135400	I.M.H.	CRediT	Conceptualization|Methodology|Formal analysis|Investigation|Data curation|Writing-original draft preparation|Writing-review & editing|Funding acquisition	Funding acquisition	-	Funding acquisition	YES
6165192	30135400	M.B.	CRediT	Supervision	Supervision	-	Supervision	YES
6165192	30135400	R.S.	CRediT	Conceptualization|Supervision	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6165192	30135400	R.S.	CRediT	Conceptualization|Supervision	Supervision	-	Supervision	YES
5436598	28580116	All authors	PLoS52	analysed and interpreted the data	analysed and interpreted the data	Analyzed the data	Formal analysis	YES
5436598	28580116	J.G.	PLoS52	designed the project|wrote the paper	designed the project	Conceived and designed the experiments	Methodology	YES
5436598	28580116	J.G.	PLoS52	designed the project|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5436598	28580116	M.D.	PLoS52	designed the project|wrote the paper	designed the project	Conceived and designed the experiments	Methodology	YES
5436598	28580116	M.D.	PLoS52	designed the project|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5436598	28580116	Y.L.	PLoS52	designed the project|performed the experiments|performed the experiments|wrote the paper	designed the project	Conceived and designed the experiments	Methodology	YES
5436598	28580116	Y.L.	PLoS52	designed the project|performed the experiments|performed the experiments|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5436598	28580116	Y.L.	PLoS52	designed the project|performed the experiments|performed the experiments|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5436598	28580116	Y.L.	PLoS52	designed the project|performed the experiments|performed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5647471	29062481	Babak Sokouti	1	Data collections|Analysis|Writing	Data collections	Performed the experiments	Investigation	YES
5647471	29062481	Babak Sokouti	1	Data collections|Analysis|Writing	Analysis	-	-	NO
5647471	29062481	Babak Sokouti	1	Data collections|Analysis|Writing	Writing	Wrote the paper	-	YES
5647471	29062481	Massoud Sokouti	1	Data collections|Analysis|Writing	Data collections	Performed the experiments	Investigation	YES
5647471	29062481	Massoud Sokouti	1	Data collections|Analysis|Writing	Analysis	-	-	NO
5647471	29062481	Massoud Sokouti	1	Data collections|Analysis|Writing	Writing	Wrote the paper	-	YES
5647471	29062481	Mohsen Sokouti	1	Design|Data collections|Writing	Design	Conceived and designed the experiments	-	YES
5647471	29062481	Mohsen Sokouti	1	Design|Data collections|Writing	Data collections	Performed the experiments	Investigation	YES
5647471	29062481	Mohsen Sokouti	1	Design|Data collections|Writing	Writing	Wrote the paper	-	YES
5647471	29062481	Morteza Ghojazadeh	1	Analysis|Writing	Analysis	-	-	NO
5647471	29062481	Morteza Ghojazadeh	1	Analysis|Writing	Writing	Wrote the paper	-	YES
4956731	27443273	CB	PLoS52	conceived the study and contributed to the study design|revised the manuscript	conceived the study and contributed to the study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4956731	27443273	CB	PLoS52	conceived the study and contributed to the study design|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4956731	27443273	CI	PLoS52	conceived the study and contributed to the study design|analysed the data|drafted the manuscript	conceived the study and contributed to the study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4956731	27443273	CI	PLoS52	conceived the study and contributed to the study design|analysed the data|drafted the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
4956731	27443273	CI	PLoS52	conceived the study and contributed to the study design|analysed the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4956731	27443273	JB	PLoS52	conceived the study and contributed to the study design|revised the manuscript	conceived the study and contributed to the study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4956731	27443273	JB	PLoS52	conceived the study and contributed to the study design|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4956731	27443273	JC	PLoS52	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4956731	27443273	JM	PLoS52	conceived the study and contributed to the study design|revised the manuscript	conceived the study and contributed to the study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4956731	27443273	JM	PLoS52	conceived the study and contributed to the study design|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4956731	27443273	JP	PLoS52	conceived the study and contributed to the study design|revised the manuscript	conceived the study and contributed to the study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4956731	27443273	JP	PLoS52	conceived the study and contributed to the study design|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4956731	27443273	LV	PLoS52	analysed the data|revised the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
4956731	27443273	LV	PLoS52	analysed the data|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4956731	27443273	MJ	PLoS52	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4956731	27443273	OA	PLoS52	analysed the data|revised the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
4956731	27443273	OA	PLoS52	analysed the data|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4956731	27443273	PA	PLoS52	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4956731	27443273	SC	PLoS52	conceived the study and contributed to the study design|revised the manuscript	conceived the study and contributed to the study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4956731	27443273	SC	PLoS52	conceived the study and contributed to the study design|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4956731	27443273	SG	PLoS52	conceived the study and contributed to the study design|analysed the data|drafted the manuscript	conceived the study and contributed to the study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4956731	27443273	SG	PLoS52	conceived the study and contributed to the study design|analysed the data|drafted the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
4956731	27443273	SG	PLoS52	conceived the study and contributed to the study design|analysed the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4956731	27443273	VW	PLoS52	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4956731	27443273	WM	PLoS52	analysed the data|revised the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
4956731	27443273	WM	PLoS52	analysed the data|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5559503	28861098	All authors	PLoS52	read and approved the manuscript	read and approved the manuscript	-	-	NO
5559503	28861098	MP	PLoS52	conceived and designed research	conceived and designed research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5559503	28861098	MPP	PLoS52	wrote manuscript	wrote manuscript	Wrote the paper	Writing - Original Draft	YES
5559503	28861098	MS	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5559503	28861098	MaK	PLoS52	conceived and designed research|wrote manuscript	conceived and designed research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5559503	28861098	MaK	PLoS52	conceived and designed research|wrote manuscript	wrote manuscript	Wrote the paper	Writing - Original Draft	YES
5559503	28861098	PR	PLoS52	conceived and designed research|revised and edit the manuscript	conceived and designed research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5559503	28861098	PR	PLoS52	conceived and designed research|revised and edit the manuscript	revised and edit the manuscript	Wrote the paper	Writing - Review & Editing	YES
5559503	28861098	TK	PLoS52	assisted in bioinformatics analysis	assisted in bioinformatics analysis	-	Formal analysis	YES
5559503	28861098	ZJ	PLoS52	conceived and designed research|wrote manuscript	conceived and designed research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5559503	28861098	ZJ	PLoS52	conceived and designed research|wrote manuscript	wrote manuscript	Wrote the paper	Writing - Original Draft	YES
5651486	29071068	All authors	2	contributed to the acquisition of clinical data	contributed to the acquisition of clinical data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4406493	25902075	CC	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406493	25902075	CC	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406493	25902075	HY	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406493	25902075	HY	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406493	25902075	HY	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406493	25902075	HY	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406493	25902075	KF	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406493	25902075	KF	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406493	25902075	KT	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406493	25902075	KT	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406493	25902075	KT	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406493	25902075	RN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406493	25902075	RN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406493	25902075	RN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406493	25902075	RN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406493	25902075	RN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406493	25902075	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406493	25902075	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406493	25902075	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406493	25902075	TM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4406493	25902075	TM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406493	25902075	TN	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406493	25902075	TN	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406493	25902075	YT	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406493	25902075	YT	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4496643	26199946	Hengfu Yin	2	contributed equally to this work	contributed equally to this work	-	-	NO
4496643	26199946	Ning Ye	2	contributed equally to this work	contributed equally to this work	-	-	NO
5312537	28201987	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5312537	28201987	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
5312537	28201987	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5312537	28201987	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5312537	28201987	JH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5312537	28201987	JH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5312537	28201987	JH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5312537	28201987	JS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5312537	28201987	MW	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5312537	28201987	MW	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5312537	28201987	NZ	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5312537	28201987	NZ	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3337556	22570772	F. Ojini	2	reviewed the manuscript for intellectual content and approved the final version	reviewed the manuscript for intellectual content and approved the final version	Wrote the paper	Writing - Review & Editing	YES
3337556	22570772	M. Danesi	2	reviewed the manuscript for intellectual content and approved the final version	reviewed the manuscript for intellectual content and approved the final version	Wrote the paper	Writing - Review & Editing	YES
3337556	22570772	N. Okubadejo	2	reviewed the manuscript for intellectual content and approved the final version	reviewed the manuscript for intellectual content and approved the final version	Wrote the paper	Writing - Review & Editing	YES
4956732	27443267	All authors	2	provided critical review and comments and approved the final manuscript	provided critical review and comments and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4956732	27443267	KH	2	oversaw the data collection|conducted the data analysis	oversaw the data collection	Performed the experiments	Investigation|Supervision	YES
4956732	27443267	KH	2	oversaw the data collection|conducted the data analysis	conducted the data analysis	Analyzed the data	Formal analysis	YES
4956732	27443267	LK	2	contributed to the intervention design|oversaw the data collection	contributed to the intervention design	Conceived and designed the experiments	-	YES
4956732	27443267	LK	2	contributed to the intervention design|oversaw the data collection	oversaw the data collection	Performed the experiments	Investigation|Supervision	YES
4956732	27443267	LV	2	conducted the data analysis|drafted the manuscript	conducted the data analysis	Analyzed the data	Formal analysis	YES
4956732	27443267	LV	2	conducted the data analysis|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4956732	27443267	NJ	2	conceived the study|oversaw the data collection|drafted the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4956732	27443267	NJ	2	conceived the study|oversaw the data collection|drafted the manuscript	oversaw the data collection	Performed the experiments	Investigation|Supervision	YES
4956732	27443267	NJ	2	conceived the study|oversaw the data collection|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4956732	27443267	SK	2	conceived the study|oversaw the data collection	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4956732	27443267	SK	2	conceived the study|oversaw the data collection	oversaw the data collection	Performed the experiments	Investigation|Supervision	YES
5559511	28861099	BM	2	conceived and contributed toward the writing of specific parts of the article and in its critical revision	conceived and contributed toward the writing of specific parts of the article and in its critical revision	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
5559511	28861099	CL	2	designed and contributed to the writing of the main body of article	designed and contributed to the writing of the main body of article	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
5559511	28861099	JS	2	contributed to the development of specific parts of the article and to its critical revision	contributed to the development of specific parts of the article and to its critical revision	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5559511	28861099	SS	2	contributed by writing specific parts of the article and revising it critically	contributed by writing specific parts of the article and revising it critically	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5559511	28861099	The authors	2	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	Performed the experiments	Investigation	YES
5651492	29071067	C. Macano	7	Writing the paper, data collection	Writing the paper, data collection	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5651492	29071067	G. Kirby	7	Writing the paper, data collection and analysis	Writing the paper, data collection and analysis	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5651492	29071067	M. Richardson	7	Study concept, data collection, review and editing of paper	Study concept, data collection, review and editing of paper	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Review & Editing	YES
5651492	29071067	R. Nijjar	7	Data collection; project conception; review and editing of the manuscript	Data collection; project conception; review and editing of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Review & Editing	YES
5651492	29071067	R. Singhal	7	Study concept, data collection, review and editing of paper	Study concept, data collection, review and editing of paper	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Review & Editing	YES
5651492	29071067	S. Nyasavajjala	7	Writing the paper, data collection. M. Daskalakis. Data collection, review and editing of paper	Writing the paper, data collection. M. Daskalakis. Data collection, review and editing of paper	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5789554	29416212	AA	2	made the substantial contribution to conception, design, drafting the article and critical revision for important intellectual content	made the substantial contribution to conception, design, drafting the article and critical revision for important intellectual content	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
5789554	29416212	FR	2	made the substantial contribution to conception, design, drafting the article and critical revision for important intellectual content	made the substantial contribution to conception, design, drafting the article and critical revision for important intellectual content	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
5789554	29416212	GHA	2	made the substantial contribution to conception, design, drafting the article and critical revision for important intellectual content	made the substantial contribution to conception, design, drafting the article and critical revision for important intellectual content	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
5789554	29416212	HS	2	made final modification the article	made final modification the article	Wrote the paper	Writing - Review & Editing	YES
5559532	28861100	HN	2	have co-edited the topic and co-prepared the editorial	have co-edited the topic and co-prepared the editorial	Wrote the paper	Writing - Review & Editing	YES
5559532	28861100	RB	2	have co-edited the topic and co-prepared the editorial	have co-edited the topic and co-prepared the editorial	Wrote the paper	Writing - Review & Editing	YES
5559532	28861100	RD	2	have co-edited the topic and co-prepared the editorial	have co-edited the topic and co-prepared the editorial	Wrote the paper	Writing - Review & Editing	YES
6165212	30217022	E.A.A.	CRediT	Conceptualization|Methodology|Validation|Formal analysis|Investigation|Resources|Data curation|Writing--original draft preparation|Visualization	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6165212	30217022	E.A.A.	CRediT	Conceptualization|Methodology|Validation|Formal analysis|Investigation|Resources|Data curation|Writing--original draft preparation|Visualization	Methodology	Performed the experiments	Methodology	YES
6165212	30217022	E.A.A.	CRediT	Conceptualization|Methodology|Validation|Formal analysis|Investigation|Resources|Data curation|Writing--original draft preparation|Visualization	Validation	Performed the experiments	Validation	YES
6165212	30217022	E.A.A.	CRediT	Conceptualization|Methodology|Validation|Formal analysis|Investigation|Resources|Data curation|Writing--original draft preparation|Visualization	Formal analysis	Analyzed the data	Formal analysis	YES
6165212	30217022	E.A.A.	CRediT	Conceptualization|Methodology|Validation|Formal analysis|Investigation|Resources|Data curation|Writing--original draft preparation|Visualization	Investigation	Performed the experiments	Investigation	YES
6165212	30217022	E.A.A.	CRediT	Conceptualization|Methodology|Validation|Formal analysis|Investigation|Resources|Data curation|Writing--original draft preparation|Visualization	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6165212	30217022	E.A.A.	CRediT	Conceptualization|Methodology|Validation|Formal analysis|Investigation|Resources|Data curation|Writing--original draft preparation|Visualization	Data curation	Analyzed the data	Data curation	YES
6165212	30217022	E.A.A.	CRediT	Conceptualization|Methodology|Validation|Formal analysis|Investigation|Resources|Data curation|Writing--original draft preparation|Visualization	Writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6165212	30217022	E.A.A.	CRediT	Conceptualization|Methodology|Validation|Formal analysis|Investigation|Resources|Data curation|Writing--original draft preparation|Visualization	Visualization	Analyzed the data	Visualization	YES
6165212	30217022	J.S.	CRediT	Validation|Resources|Data curation|Writing--review & editing|Visualization|Supervision|Project administration	Validation	Performed the experiments	Validation	YES
6165212	30217022	J.S.	CRediT	Validation|Resources|Data curation|Writing--review & editing|Visualization|Supervision|Project administration	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6165212	30217022	J.S.	CRediT	Validation|Resources|Data curation|Writing--review & editing|Visualization|Supervision|Project administration	Data curation	Analyzed the data	Data curation	YES
6165212	30217022	J.S.	CRediT	Validation|Resources|Data curation|Writing--review & editing|Visualization|Supervision|Project administration	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6165212	30217022	J.S.	CRediT	Validation|Resources|Data curation|Writing--review & editing|Visualization|Supervision|Project administration	Visualization	Analyzed the data	Visualization	YES
6165212	30217022	J.S.	CRediT	Validation|Resources|Data curation|Writing--review & editing|Visualization|Supervision|Project administration	Supervision	-	Supervision	YES
6165212	30217022	J.S.	CRediT	Validation|Resources|Data curation|Writing--review & editing|Visualization|Supervision|Project administration	Project administration	-	Project administration	YES
6165212	30217022	M.W.	CRediT	Conceptualization|Methodology|Validation|Formal analysis|Resources|Data curation|Writing--review & editing|Visualization|Supervision|Project administration	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6165212	30217022	M.W.	CRediT	Conceptualization|Methodology|Validation|Formal analysis|Resources|Data curation|Writing--review & editing|Visualization|Supervision|Project administration	Methodology	Performed the experiments	Methodology	YES
6165212	30217022	M.W.	CRediT	Conceptualization|Methodology|Validation|Formal analysis|Resources|Data curation|Writing--review & editing|Visualization|Supervision|Project administration	Validation	Performed the experiments	Validation	YES
6165212	30217022	M.W.	CRediT	Conceptualization|Methodology|Validation|Formal analysis|Resources|Data curation|Writing--review & editing|Visualization|Supervision|Project administration	Formal analysis	Analyzed the data	Formal analysis	YES
6165212	30217022	M.W.	CRediT	Conceptualization|Methodology|Validation|Formal analysis|Resources|Data curation|Writing--review & editing|Visualization|Supervision|Project administration	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6165212	30217022	M.W.	CRediT	Conceptualization|Methodology|Validation|Formal analysis|Resources|Data curation|Writing--review & editing|Visualization|Supervision|Project administration	Data curation	Analyzed the data	Data curation	YES
6165212	30217022	M.W.	CRediT	Conceptualization|Methodology|Validation|Formal analysis|Resources|Data curation|Writing--review & editing|Visualization|Supervision|Project administration	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6165212	30217022	M.W.	CRediT	Conceptualization|Methodology|Validation|Formal analysis|Resources|Data curation|Writing--review & editing|Visualization|Supervision|Project administration	Visualization	Analyzed the data	Visualization	YES
6165212	30217022	M.W.	CRediT	Conceptualization|Methodology|Validation|Formal analysis|Resources|Data curation|Writing--review & editing|Visualization|Supervision|Project administration	Supervision	-	Supervision	YES
6165212	30217022	M.W.	CRediT	Conceptualization|Methodology|Validation|Formal analysis|Resources|Data curation|Writing--review & editing|Visualization|Supervision|Project administration	Project administration	-	Project administration	YES
4406495	25901604	AD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Developed apparatus and methods	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406495	25901604	AD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Developed apparatus and methods	Performed the experiments	Performed the experiments	Investigation	YES
4406495	25901604	AD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Developed apparatus and methods	Analyzed the data	Analyzed the data	Formal analysis	YES
4406495	25901604	AD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Developed apparatus and methods	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406495	25901604	AD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Developed apparatus and methods	Developed apparatus and methods	Performed the experiments	Methodology	YES
4406495	25901604	AG	PLoS5	Conceived and designed the experiments|Developed apparatus and methods|Reviewed manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406495	25901604	AG	PLoS5	Conceived and designed the experiments|Developed apparatus and methods|Reviewed manuscript	Developed apparatus and methods	Performed the experiments	Methodology	YES
4406495	25901604	AG	PLoS5	Conceived and designed the experiments|Developed apparatus and methods|Reviewed manuscript	Reviewed manuscript	Wrote the paper	Writing - Review & Editing	YES
4406495	25901604	MB	PLoS5	Conceived and designed the experiments|Reviewed statistical analysis|Reviewed manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406495	25901604	MB	PLoS5	Conceived and designed the experiments|Reviewed statistical analysis|Reviewed manuscript	Reviewed statistical analysis	Analyzed the data	Formal analysis	YES
4406495	25901604	MB	PLoS5	Conceived and designed the experiments|Reviewed statistical analysis|Reviewed manuscript	Reviewed manuscript	Wrote the paper	Writing - Review & Editing	YES
4406495	25901604	TS	PLoS5	Conceived and designed the experiments|Reviewed statistical analysis|Reviewed manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406495	25901604	TS	PLoS5	Conceived and designed the experiments|Reviewed statistical analysis|Reviewed manuscript	Reviewed statistical analysis	Analyzed the data	Formal analysis	YES
4406495	25901604	TS	PLoS5	Conceived and designed the experiments|Reviewed statistical analysis|Reviewed manuscript	Reviewed manuscript	Wrote the paper	Writing - Review & Editing	YES
4956733	27443268	AA	2	contributed to protocol and manuscript development	contributed to protocol and manuscript development	Conceived and designed the experiments	Methodology	YES
4956733	27443268	DN	2	was responsible for data collection, study coordination, analysis and interpretation of the findings	was responsible for data collection, study coordination, analysis and interpretation of the findings	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Project administration	YES
4956733	27443268	GW	2	was responsible for developing the study protocol as well as conducting the analysis and interpretation of data	was responsible for developing the study protocol as well as conducting the analysis and interpretation of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
4956733	27443268	MR	2	contributed to protocol development and review of the manuscript	contributed to protocol development and review of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft|Writing - Review & Editing	YES
4956733	27443268	PM	2	contributed to protocol development and review of the manuscript	contributed to protocol development and review of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft|Writing - Review & Editing	YES
4956733	27443268	RP	2	contributed to protocol and manuscript development	contributed to protocol and manuscript development	Conceived and designed the experiments	Methodology	YES
4956733	27443268	SB	2	was responsible for drafting the manuscript as well as interpretation of the data	was responsible for drafting the manuscript as well as interpretation of the data	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5312539	28201990	AS	PLoS52	conceived and designed the experiments|analyzed data|wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5312539	28201990	AS	PLoS52	conceived and designed the experiments|analyzed data|wrote the manuscript	analyzed data	Analyzed the data	Formal analysis	YES
5312539	28201990	AS	PLoS52	conceived and designed the experiments|analyzed data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5312539	28201990	DM	PLoS52	carried out all experiments|analyzed data	carried out all experiments	Performed the experiments	Investigation	YES
5312539	28201990	DM	PLoS52	carried out all experiments|analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5312539	28201990	HV	PLoS52	conceived and designed the experiments|carried out all experiments|analyzed data|wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5312539	28201990	HV	PLoS52	conceived and designed the experiments|carried out all experiments|analyzed data|wrote the manuscript	carried out all experiments	Performed the experiments	Investigation	YES
5312539	28201990	HV	PLoS52	conceived and designed the experiments|carried out all experiments|analyzed data|wrote the manuscript	analyzed data	Analyzed the data	Formal analysis	YES
5312539	28201990	HV	PLoS52	conceived and designed the experiments|carried out all experiments|analyzed data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5312539	28201990	MJ	PLoS52	carried out all experiments|analyzed data	carried out all experiments	Performed the experiments	Investigation	YES
5312539	28201990	MJ	PLoS52	carried out all experiments|analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5312539	28201990	MS	PLoS52	carried out all experiments|analyzed data	carried out all experiments	Performed the experiments	Investigation	YES
5312539	28201990	MS	PLoS52	carried out all experiments|analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5312539	28201990	SS	PLoS52	carried out all experiments|analyzed data	carried out all experiments	Performed the experiments	Investigation	YES
5312539	28201990	SS	PLoS52	carried out all experiments|analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5559686	28861093	IAS	2	co-ordinated the work and secured fundings	co-ordinated the work and secured fundings	-	Funding acquisition|Project administration	YES
5559686	28861093	M-YW	2	co-ordinated the work and secured fundings	co-ordinated the work and secured fundings	-	Funding acquisition|Project administration	YES
5559686	28861093	MM	2	co-ordinated the work and secured fundings	co-ordinated the work and secured fundings	-	Funding acquisition|Project administration	YES
5559686	28861093	NTG	2	conducted the experiment, analyses and wrote the manuscript	conducted the experiment, analyses and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5656756	29098077	S. Nyasavajjala	2	writing and editing the paper	writing and editing the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3676907	23762569	A. Boddy	2	advised on and carried out statistical analysis	advised on and carried out statistical analysis	Analyzed the data	Formal analysis	YES
3676907	23762569	A. Godden	2	conceived, designed, and carried out the study	conceived, designed, and carried out the study	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
3676907	23762569	T. Fysh	2	conceived, designed, and carried out the study	conceived, designed, and carried out the study	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
5789556	29416221	AP	2	contributed to analysis and interpretation of data, and assisted in the preparation of the manuscript|reviewed and approved the final version of the manuscript	contributed to analysis and interpretation of data, and assisted in the preparation of the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
5789556	29416221	AP	2	contributed to analysis and interpretation of data, and assisted in the preparation of the manuscript|reviewed and approved the final version of the manuscript	reviewed and approved the final version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5789556	29416221	EF	2	designed the study, and wrote the initial draft of the manuscript|reviewed and approved the final version of the manuscript	designed the study, and wrote the initial draft of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5789556	29416221	EF	2	designed the study, and wrote the initial draft of the manuscript|reviewed and approved the final version of the manuscript	reviewed and approved the final version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5789556	29416221	IP	2	designed the study, and wrote the initial draft of the manuscript|reviewed and approved the final version of the manuscript	designed the study, and wrote the initial draft of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5789556	29416221	IP	2	designed the study, and wrote the initial draft of the manuscript|reviewed and approved the final version of the manuscript	reviewed and approved the final version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5789556	29416221	KT	2	designed the study, and wrote the initial draft of the manuscript|reviewed and approved the final version of the manuscript	designed the study, and wrote the initial draft of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5789556	29416221	KT	2	designed the study, and wrote the initial draft of the manuscript|reviewed and approved the final version of the manuscript	reviewed and approved the final version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5789556	29416221	MAK	2	contributed to analysis and interpretation of data, and assisted in the preparation of the manuscript|reviewed and approved the final version of the manuscript	contributed to analysis and interpretation of data, and assisted in the preparation of the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
5789556	29416221	MAK	2	contributed to analysis and interpretation of data, and assisted in the preparation of the manuscript|reviewed and approved the final version of the manuscript	reviewed and approved the final version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5789556	29416221	MK	2	designed the study, and wrote the initial draft of the manuscript|contributed to analysis and interpretation of data, and assisted in the preparation of the manuscript|reviewed and approved the final version of the manuscript	designed the study, and wrote the initial draft of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5789556	29416221	MK	2	designed the study, and wrote the initial draft of the manuscript|contributed to analysis and interpretation of data, and assisted in the preparation of the manuscript|reviewed and approved the final version of the manuscript	contributed to analysis and interpretation of data, and assisted in the preparation of the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
5789556	29416221	MK	2	designed the study, and wrote the initial draft of the manuscript|contributed to analysis and interpretation of data, and assisted in the preparation of the manuscript|reviewed and approved the final version of the manuscript	reviewed and approved the final version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5789556	29416221	VV	2	contributed to analysis and interpretation of data, and assisted in the preparation of the manuscript|reviewed and approved the final version of the manuscript	contributed to analysis and interpretation of data, and assisted in the preparation of the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
5789556	29416221	VV	2	contributed to analysis and interpretation of data, and assisted in the preparation of the manuscript|reviewed and approved the final version of the manuscript	reviewed and approved the final version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4406496	25901571	EJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406496	25901571	EJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4406496	25901571	EJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406496	25901571	JFV	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406496	25901571	MJ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406496	25901571	MV	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406496	25901571	MV	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406496	25901571	MV	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406496	25901571	PC	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406496	25901571	PC	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406496	25901571	PG	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406496	25901571	PG	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406496	25901571	PG	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406496	25901571	PG	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406496	25901571	UM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406496	25901571	UM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406496	25901571	UM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406496	25901571	UM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406496	25901571	XB	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406496	25901571	XB	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
6165228	29954141	A.Z.N.	2	refined the procedures for neurocognitive testing|provided input on data analysis and the interpretation of results|revised the manuscript	refined the procedures for neurocognitive testing	Performed the experiments	Investigation	YES
6165228	29954141	A.Z.N.	2	refined the procedures for neurocognitive testing|provided input on data analysis and the interpretation of results|revised the manuscript	provided input on data analysis and the interpretation of results	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6165228	29954141	A.Z.N.	2	refined the procedures for neurocognitive testing|provided input on data analysis and the interpretation of results|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
6165228	29954141	B.G.G.	2	performed the statistical analyses|provided input on data analysis and the interpretation of results|revised the manuscript	performed the statistical analyses	Analyzed the data	Formal analysis	YES
6165228	29954141	B.G.G.	2	performed the statistical analyses|provided input on data analysis and the interpretation of results|revised the manuscript	provided input on data analysis and the interpretation of results	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6165228	29954141	B.G.G.	2	performed the statistical analyses|provided input on data analysis and the interpretation of results|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
6165228	29954141	E.S.R.	2	refined the procedures for neurocognitive testing|provided input on data analysis and the interpretation of results|revised the manuscript	refined the procedures for neurocognitive testing	Performed the experiments	Investigation	YES
6165228	29954141	E.S.R.	2	refined the procedures for neurocognitive testing|provided input on data analysis and the interpretation of results|revised the manuscript	provided input on data analysis and the interpretation of results	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6165228	29954141	E.S.R.	2	refined the procedures for neurocognitive testing|provided input on data analysis and the interpretation of results|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
6165228	29954141	K.A.D.L.	2	performed the statistical analyses|provided input on data analysis and the interpretation of results|revised the manuscript	performed the statistical analyses	Analyzed the data	Formal analysis	YES
6165228	29954141	K.A.D.L.	2	performed the statistical analyses|provided input on data analysis and the interpretation of results|revised the manuscript	provided input on data analysis and the interpretation of results	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6165228	29954141	K.A.D.L.	2	performed the statistical analyses|provided input on data analysis and the interpretation of results|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
6165228	29954141	L.L.W.	2	conceived the basic idea, initiated, designed and directed the study and wrote the manuscript|refined the procedures for neurocognitive testing|provided input on data analysis and the interpretation of results|revised the manuscript	conceived the basic idea, initiated, designed and directed the study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Supervision|Writing - Original Draft	YES
6165228	29954141	L.L.W.	2	conceived the basic idea, initiated, designed and directed the study and wrote the manuscript|refined the procedures for neurocognitive testing|provided input on data analysis and the interpretation of results|revised the manuscript	refined the procedures for neurocognitive testing	Performed the experiments	Investigation	YES
6165228	29954141	L.L.W.	2	conceived the basic idea, initiated, designed and directed the study and wrote the manuscript|refined the procedures for neurocognitive testing|provided input on data analysis and the interpretation of results|revised the manuscript	provided input on data analysis and the interpretation of results	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6165228	29954141	L.L.W.	2	conceived the basic idea, initiated, designed and directed the study and wrote the manuscript|refined the procedures for neurocognitive testing|provided input on data analysis and the interpretation of results|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
6165228	29954141	T.L.W.	2	conceived the basic idea, initiated, designed and directed the study and wrote the manuscript|refined the procedures for neurocognitive testing|performed the statistical analyses|performed the statistical analyses|provided input on data analysis and the interpretation of results|revised the manuscript	conceived the basic idea, initiated, designed and directed the study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Supervision|Writing - Original Draft	YES
6165228	29954141	T.L.W.	2	conceived the basic idea, initiated, designed and directed the study and wrote the manuscript|refined the procedures for neurocognitive testing|performed the statistical analyses|performed the statistical analyses|provided input on data analysis and the interpretation of results|revised the manuscript	refined the procedures for neurocognitive testing	Performed the experiments	Investigation	YES
6165228	29954141	T.L.W.	2	conceived the basic idea, initiated, designed and directed the study and wrote the manuscript|refined the procedures for neurocognitive testing|performed the statistical analyses|performed the statistical analyses|provided input on data analysis and the interpretation of results|revised the manuscript	performed the statistical analyses	Analyzed the data	Formal analysis	YES
6165228	29954141	T.L.W.	2	conceived the basic idea, initiated, designed and directed the study and wrote the manuscript|refined the procedures for neurocognitive testing|performed the statistical analyses|performed the statistical analyses|provided input on data analysis and the interpretation of results|revised the manuscript	performed the statistical analyses	Analyzed the data	Formal analysis	YES
6165228	29954141	T.L.W.	2	conceived the basic idea, initiated, designed and directed the study and wrote the manuscript|refined the procedures for neurocognitive testing|performed the statistical analyses|performed the statistical analyses|provided input on data analysis and the interpretation of results|revised the manuscript	provided input on data analysis and the interpretation of results	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6165228	29954141	T.L.W.	2	conceived the basic idea, initiated, designed and directed the study and wrote the manuscript|refined the procedures for neurocognitive testing|performed the statistical analyses|performed the statistical analyses|provided input on data analysis and the interpretation of results|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5671385	29123655	Arif Ali	2	were involved in data collection	were involved in data collection	Performed the experiments	Investigation	YES
5671385	29123655	Azeem Tariq Malik	2	was involved in conception of idea, data collection and analysis, manuscript writing and reviewal	was involved in conception of idea, data collection and analysis, manuscript writing and reviewal	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5671385	29123655	Shahryar Noordin	2	was involved in reviewal of manuscript	was involved in reviewal of manuscript	Wrote the paper	Writing - Review & Editing	YES
5671385	29123655	Syed Hamza Mufarrih	2	were involved in data collection	were involved in data collection	Performed the experiments	Investigation	YES
4956734	27443266	CMN	2	provided technical input in the conception of the study and contributed to interpretation	provided technical input in the conception of the study and contributed to interpretation	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
4956734	27443266	EN	2	were co-investigators and served on the advisory board	were co-investigators and served on the advisory board	-	-	NO
4956734	27443266	FM	2	were co-investigators and served on the advisory board	were co-investigators and served on the advisory board	-	-	NO
4956734	27443266	GM	2	coordinated data collection activities in their respective countries	coordinated data collection activities in their respective countries	Performed the experiments	Investigation|Project administration	YES
4956734	27443266	HA	2	coordinated data collection activities in their respective countries	coordinated data collection activities in their respective countries	Performed the experiments	Investigation|Project administration	YES
4956734	27443266	JO	2	was co-investigator, conducted analysis and wrote portions of the manuscript	was co-investigator, conducted analysis and wrote portions of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4956734	27443266	KS	2	was co-investigator, led the analysis and helped draft the manuscript	was co-investigator, led the analysis and helped draft the manuscript	Wrote the paper	Writing - Original Draft	YES
4956734	27443266	RK	2	were co-investigators and served on the advisory board	were co-investigators and served on the advisory board	-	-	NO
4956734	27443266	SE	2	coordinated data collection activities in their respective countries	coordinated data collection activities in their respective countries	Performed the experiments	Investigation|Project administration	YES
4956734	27443266	WT	2	was the principal investigator of the study and led the writing of the manuscript	was the principal investigator of the study and led the writing of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Funding acquisition|Writing - Original Draft	YES
5312572	28201982	HZL	2	participated in the design and coordination of the study, and drafted the manuscript	participated in the design and coordination of the study, and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft	YES
5312572	28201982	JGH	2	participated in the design and coordination of the study, and drafted the manuscript	participated in the design and coordination of the study, and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft	YES
5312572	28201982	JSZ	2	conducted data analysis and interpretation	conducted data analysis and interpretation	Analyzed the data	Formal analysis	YES
5312572	28201982	LLS	2	conducted data analysis and interpretation	conducted data analysis and interpretation	Analyzed the data	Formal analysis	YES
5312572	28201982	LS	2	conducted data analysis and interpretation	conducted data analysis and interpretation	Analyzed the data	Formal analysis	YES
5312572	28201982	NZ	2	performed animal experimental procedures and rna sample collection	performed animal experimental procedures and rna sample collection	Performed the experiments	Investigation	YES
5312572	28201982	RW	2	conducted data analysis and interpretation	conducted data analysis and interpretation	Analyzed the data	Formal analysis	YES
5312572	28201982	XMX	2	performed animal experimental procedures and rna sample collection	performed animal experimental procedures and rna sample collection	Performed the experiments	Investigation	YES
5312572	28201982	YJC	2	performed animal experimental procedures and rna sample collection	performed animal experimental procedures and rna sample collection	Performed the experiments	Investigation	YES
5789557	29416210	E.H.	5	performed each step of research and gave final approval for article publishing	performed each step of research and gave final approval for article publishing	Performed the experiments	Investigation	YES
6165248	29954051	L.C.	2	conceived and designed the lecture topic|reviewed and edited the manuscript	conceived and designed the lecture topic	Conceived and designed the experiments	Conceptualization	YES
6165248	29954051	L.C.	2	conceived and designed the lecture topic|reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
6165248	29954051	R.H.P.II	2	conceived and designed the lecture topic|wrote and delivered the lecture, and wrote the manuscript	conceived and designed the lecture topic	Conceived and designed the experiments	Conceptualization	YES
6165248	29954051	R.H.P.II	2	conceived and designed the lecture topic|wrote and delivered the lecture, and wrote the manuscript	wrote and delivered the lecture, and wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4406497	25901610	BC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406497	25901610	DQG	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406497	25901610	GHH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406497	25901610	GHH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406497	25901610	GHH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406497	25901610	GHH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406497	25901610	GHH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406497	25901610	JHJ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406497	25901610	JY	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406497	25901610	WGF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406497	25901610	WGF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406497	25901610	WGF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406497	25901610	WGF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406497	25901610	XX	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406497	25901610	YQW	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
3687507	23862068	Akbari Atieh	2	have contributed to design project and gathered and managed the data set	have contributed to design project and gathered and managed the data set	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Investigation|Methodology|Project administration|Resources	YES
3687507	23862068	Akbari Mohammad Esmaeil	2	coordinated and supervised the project and wrote the first draft paper	coordinated and supervised the project and wrote the first draft paper	Wrote the paper	Project administration|Supervision|Writing - Original Draft	YES
3687507	23862068	Ansari Maryam	2	have contributed to design project and gathered and managed the data set	have contributed to design project and gathered and managed the data set	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Investigation|Methodology|Project administration|Resources	YES
3687507	23862068	Ebrahimi Mandana	2	contributed as the experts to discuss the results and provide the final draft of paper	contributed as the experts to discuss the results and provide the final draft of paper	Wrote the paper	Writing - Original Draft	YES
3687507	23862068	Haghighat Shahpar	2	coordinated and supervised the project and wrote the first draft paper|have analyzed the data	coordinated and supervised the project and wrote the first draft paper	Wrote the paper	Project administration|Supervision|Writing - Original Draft	YES
3687507	23862068	Haghighat Shahpar	2	coordinated and supervised the project and wrote the first draft paper|have analyzed the data	have analyzed the data	Analyzed the data	Formal analysis	YES
3687507	23862068	Homaei Shandiz Fatemeh	2	have contributed to design project and gathered and managed the data set	have contributed to design project and gathered and managed the data set	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Investigation|Methodology|Project administration|Resources	YES
3687507	23862068	Mirzaei Hamid Reza	2	contributed as the experts to discuss the results and provide the final draft of paper	contributed as the experts to discuss the results and provide the final draft of paper	Wrote the paper	Writing - Original Draft	YES
3687507	23862068	Najafi Massoome	2	contributed as the experts to discuss the results and provide the final draft of paper	contributed as the experts to discuss the results and provide the final draft of paper	Wrote the paper	Writing - Original Draft	YES
3687507	23862068	Yunesian Masud	2	have analyzed the data	have analyzed the data	Analyzed the data	Formal analysis	YES
5559696	28861095	BH	2	contributed to the collection of plant sample and dna and rna extraction	contributed to the collection of plant sample and dna and rna extraction	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5559696	28861095	DG	2	carried out the annotation of unigenes and gene chip data and wrote the manuscript|was responsible for qrt pcr and bioinformatics analysis and metabolites data	carried out the annotation of unigenes and gene chip data and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Formal analysis|Investigation|Writing - Original Draft	YES
5559696	28861095	DG	2	carried out the annotation of unigenes and gene chip data and wrote the manuscript|was responsible for qrt pcr and bioinformatics analysis and metabolites data	was responsible for qrt pcr and bioinformatics analysis and metabolites data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5559696	28861095	DL	2	clone the gene	clone the gene	-	-	NO
5559696	28861095	MG	2	carried out the annotation of unigenes and gene chip data and wrote the manuscript|designed the experiment and initiated the project	carried out the annotation of unigenes and gene chip data and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Formal analysis|Investigation|Writing - Original Draft	YES
5559696	28861095	MG	2	carried out the annotation of unigenes and gene chip data and wrote the manuscript|designed the experiment and initiated the project	designed the experiment and initiated the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5559696	28861095	XD	2	analyzed the metabolites	analyzed the metabolites	Analyzed the data	Formal analysis	YES
5559696	28861095	XJ	2	contributed to the collection of plant sample and dna and rna extraction	contributed to the collection of plant sample and dna and rna extraction	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5559696	28861095	YX	2	clone the gene	clone the gene	-	-	NO
5671395	29123656	Nicolo Bertozzi	2	writing and final revision of the manuscript	writing and final revision of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5671395	29123656	Raposio Edoardo	2	study design	study design	Conceived and designed the experiments	Methodology	YES
5312585	28202015	ASV	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
5312585	28202015	ASV	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5312585	28202015	ASV	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5312585	28202015	BGG	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
5312585	28202015	BGG	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5312585	28202015	CK	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5312585	28202015	GTK	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5312585	28202015	JJA	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5312585	28202015	JJA	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
5312585	28202015	JJA	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6165278	30004399	Both authors	2	designed the survey, analysed the findings, and wrote the paper	designed the survey, analysed the findings, and wrote the paper	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4956735	27443271	AIY	2	interpreted the data	interpreted the data	Analyzed the data	Formal analysis	YES
4956735	27443271	AS	2	contributed to subsequent revisions	contributed to subsequent revisions	Wrote the paper	Writing - Review & Editing	YES
4956735	27443271	AY	2	contributed to subsequent revisions	contributed to subsequent revisions	Wrote the paper	Writing - Review & Editing	YES
4956735	27443271	CB	2	collected the data|conducted or contributed to the data analysis	collected the data	Performed the experiments	Investigation	YES
4956735	27443271	CB	2	collected the data|conducted or contributed to the data analysis	conducted or contributed to the data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4956735	27443271	CD	2	interpreted the data	interpreted the data	Analyzed the data	Formal analysis	YES
4956735	27443271	DK	2	collected the data	collected the data	Performed the experiments	Investigation	YES
4956735	27443271	DMM	2	contributed to subsequent revisions	contributed to subsequent revisions	Wrote the paper	Writing - Review & Editing	YES
4956735	27443271	JB	2	supervised data collection of the study	supervised data collection of the study	Performed the experiments	Investigation|Supervision	YES
4956735	27443271	LJO	2	collected the data|conducted or contributed to the data analysis|interpreted the data	collected the data	Performed the experiments	Investigation	YES
4956735	27443271	LJO	2	collected the data|conducted or contributed to the data analysis|interpreted the data	conducted or contributed to the data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4956735	27443271	LJO	2	collected the data|conducted or contributed to the data analysis|interpreted the data	interpreted the data	Analyzed the data	Formal analysis	YES
4956735	27443271	LS	2	designed the study|collected the data|conducted or contributed to the data analysis|interpreted the data	designed the study	Conceived and designed the experiments	Methodology	YES
4956735	27443271	LS	2	designed the study|collected the data|conducted or contributed to the data analysis|interpreted the data	collected the data	Performed the experiments	Investigation	YES
4956735	27443271	LS	2	designed the study|collected the data|conducted or contributed to the data analysis|interpreted the data	conducted or contributed to the data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4956735	27443271	LS	2	designed the study|collected the data|conducted or contributed to the data analysis|interpreted the data	interpreted the data	Analyzed the data	Formal analysis	YES
4956735	27443271	SK	2	supervised data collection of the study	supervised data collection of the study	Performed the experiments	Investigation|Supervision	YES
4956735	27443271	SN	2	collected the data	collected the data	Performed the experiments	Investigation	YES
4956735	27443271	SO	2	designed the study|supervised data collection of the study|conducted or contributed to the data analysis|interpreted the data|prepared the original manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
4956735	27443271	SO	2	designed the study|supervised data collection of the study|conducted or contributed to the data analysis|interpreted the data|prepared the original manuscript	supervised data collection of the study	Performed the experiments	Investigation|Supervision	YES
4956735	27443271	SO	2	designed the study|supervised data collection of the study|conducted or contributed to the data analysis|interpreted the data|prepared the original manuscript	conducted or contributed to the data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4956735	27443271	SO	2	designed the study|supervised data collection of the study|conducted or contributed to the data analysis|interpreted the data|prepared the original manuscript	interpreted the data	Analyzed the data	Formal analysis	YES
4956735	27443271	SO	2	designed the study|supervised data collection of the study|conducted or contributed to the data analysis|interpreted the data|prepared the original manuscript	prepared the original manuscript	Wrote the paper	Writing - Original Draft	YES
4406498	25901606	GMFG	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Obtained ethical approval for completion of study|Recruited volunteers for study	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406498	25901606	GMFG	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Obtained ethical approval for completion of study|Recruited volunteers for study	Performed the experiments	Performed the experiments	Investigation	YES
4406498	25901606	GMFG	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Obtained ethical approval for completion of study|Recruited volunteers for study	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406498	25901606	GMFG	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Obtained ethical approval for completion of study|Recruited volunteers for study	Obtained ethical approval for completion of study	-	Project administration	YES
4406498	25901606	GMFG	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Obtained ethical approval for completion of study|Recruited volunteers for study	Recruited volunteers for study	Performed the experiments	Investigation	YES
4406498	25901606	JALA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406498	25901606	JALA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406498	25901606	JALA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406498	25901606	JAP	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406498	25901606	JAP	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406498	25901606	JGL	PLoS5	Conceived and designed the experiments|Wrote the paper|Obtained ethical approval for completion of study	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406498	25901606	JGL	PLoS5	Conceived and designed the experiments|Wrote the paper|Obtained ethical approval for completion of study	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406498	25901606	JGL	PLoS5	Conceived and designed the experiments|Wrote the paper|Obtained ethical approval for completion of study	Obtained ethical approval for completion of study	-	Project administration	YES
4406498	25901606	SAG	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406498	25901606	SAG	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3352252	22611485	A. Doyen	2	made the study design|were responsible for the collection of data|made the analysis|were responsible for interpretation of data|made the draft paper|prepared the final paper	made the study design	Conceived and designed the experiments	Methodology	YES
3352252	22611485	A. Doyen	2	made the study design|were responsible for the collection of data|made the analysis|were responsible for interpretation of data|made the draft paper|prepared the final paper	were responsible for the collection of data	Performed the experiments	Investigation	YES
3352252	22611485	A. Doyen	2	made the study design|were responsible for the collection of data|made the analysis|were responsible for interpretation of data|made the draft paper|prepared the final paper	made the analysis	-	-	NO
3352252	22611485	A. Doyen	2	made the study design|were responsible for the collection of data|made the analysis|were responsible for interpretation of data|made the draft paper|prepared the final paper	were responsible for interpretation of data	Analyzed the data	Formal analysis	YES
3352252	22611485	A. Doyen	2	made the study design|were responsible for the collection of data|made the analysis|were responsible for interpretation of data|made the draft paper|prepared the final paper	made the draft paper	Wrote the paper	Writing - Original Draft	YES
3352252	22611485	A. Doyen	2	made the study design|were responsible for the collection of data|made the analysis|were responsible for interpretation of data|made the draft paper|prepared the final paper	prepared the final paper	Wrote the paper	Writing - Original Draft	YES
3352252	22611485	B. Williams	2	made the study design|made the analysis|were responsible for interpretation of data|made the draft paper|prepared the final paper	made the study design	Conceived and designed the experiments	Methodology	YES
3352252	22611485	B. Williams	2	made the study design|made the analysis|were responsible for interpretation of data|made the draft paper|prepared the final paper	made the analysis	-	-	NO
3352252	22611485	B. Williams	2	made the study design|made the analysis|were responsible for interpretation of data|made the draft paper|prepared the final paper	were responsible for interpretation of data	Analyzed the data	Formal analysis	YES
3352252	22611485	B. Williams	2	made the study design|made the analysis|were responsible for interpretation of data|made the draft paper|prepared the final paper	made the draft paper	Wrote the paper	Writing - Original Draft	YES
3352252	22611485	B. Williams	2	made the study design|made the analysis|were responsible for interpretation of data|made the draft paper|prepared the final paper	prepared the final paper	Wrote the paper	Writing - Original Draft	YES
3352252	22611485	N. Garg	2	made the study design|were responsible for the collection of data|made the draft paper	made the study design	Conceived and designed the experiments	Methodology	YES
3352252	22611485	N. Garg	2	made the study design|were responsible for the collection of data|made the draft paper	were responsible for the collection of data	Performed the experiments	Investigation	YES
3352252	22611485	N. Garg	2	made the study design|were responsible for the collection of data|made the draft paper	made the draft paper	Wrote the paper	Writing - Original Draft	YES
3352252	22611485	N. Muraguri	2	made the study design|were responsible for the collection of data|were responsible for interpretation of data|were responsible for interpretation of data|made the draft paper|prepared the final paper|prepared the final paper	made the study design	Conceived and designed the experiments	Methodology	YES
3352252	22611485	N. Muraguri	2	made the study design|were responsible for the collection of data|were responsible for interpretation of data|were responsible for interpretation of data|made the draft paper|prepared the final paper|prepared the final paper	were responsible for the collection of data	Performed the experiments	Investigation	YES
3352252	22611485	N. Muraguri	2	made the study design|were responsible for the collection of data|were responsible for interpretation of data|were responsible for interpretation of data|made the draft paper|prepared the final paper|prepared the final paper	were responsible for interpretation of data	Analyzed the data	Formal analysis	YES
3352252	22611485	N. Muraguri	2	made the study design|were responsible for the collection of data|were responsible for interpretation of data|were responsible for interpretation of data|made the draft paper|prepared the final paper|prepared the final paper	were responsible for interpretation of data	Analyzed the data	Formal analysis	YES
3352252	22611485	N. Muraguri	2	made the study design|were responsible for the collection of data|were responsible for interpretation of data|were responsible for interpretation of data|made the draft paper|prepared the final paper|prepared the final paper	made the draft paper	Wrote the paper	Writing - Original Draft	YES
3352252	22611485	N. Muraguri	2	made the study design|were responsible for the collection of data|were responsible for interpretation of data|were responsible for interpretation of data|made the draft paper|prepared the final paper|prepared the final paper	prepared the final paper	Wrote the paper	Writing - Original Draft	YES
3352252	22611485	N. Muraguri	2	made the study design|were responsible for the collection of data|were responsible for interpretation of data|were responsible for interpretation of data|made the draft paper|prepared the final paper|prepared the final paper	prepared the final paper	Wrote the paper	Writing - Original Draft	YES
3352252	22611485	R. Granich	2	made the study design|made the analysis|were responsible for interpretation of data|made the draft paper|prepared the final paper	made the study design	Conceived and designed the experiments	Methodology	YES
3352252	22611485	R. Granich	2	made the study design|made the analysis|were responsible for interpretation of data|made the draft paper|prepared the final paper	made the analysis	-	-	NO
3352252	22611485	R. Granich	2	made the study design|made the analysis|were responsible for interpretation of data|made the draft paper|prepared the final paper	were responsible for interpretation of data	Analyzed the data	Formal analysis	YES
3352252	22611485	R. Granich	2	made the study design|made the analysis|were responsible for interpretation of data|made the draft paper|prepared the final paper	made the draft paper	Wrote the paper	Writing - Original Draft	YES
3352252	22611485	R. Granich	2	made the study design|made the analysis|were responsible for interpretation of data|made the draft paper|prepared the final paper	prepared the final paper	Wrote the paper	Writing - Original Draft	YES
5559707	28861092	All authors	2	contributed to and approved the final manuscript	contributed to and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5559707	28861092	JY	2	analyzed the results and revised the manuscript	analyzed the results and revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5559707	28861092	NZ	2	revised the manuscript, analyzed the results	revised the manuscript, analyzed the results	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5559707	28861092	WF	2	collected plant materials, performed the experiments, analyzed data, and wrote the first version of the manuscript	collected plant materials, performed the experiments, analyzed data, and wrote the first version of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5559707	28861092	WZ	2	analyzed the results and revised the manuscript	analyzed the results and revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5559707	28861092	XL	2	revised the manuscript, analyzed the results	revised the manuscript, analyzed the results	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5559707	28861092	YW	2	designed experiments, supervised the study, co-wrote and revised the manuscript	designed experiments, supervised the study, co-wrote and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
5559707	28861092	ZS	2	analyzed the results and revised the manuscript	analyzed the results and revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5671396	29123654	Adegbehingbe Olayinka Oladiran	7	study design, data collections. Esan Oluwadare-study design, data collection, writing	study design, data collections. Esan Oluwadare-study design, data collection, writing	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology	YES
5671396	29123654	Asuquo Joseph Effiong	7	writing. Akinyoola Lawrence-study design, writing	writing. Akinyoola Lawrence-study design, writing	Conceived and designed the experiments|Wrote the paper	Methodology	YES
5671396	29123654	Mejabi Joseph	7	study design, data collections, data analysis, writing	study design, data collections, data analysis, writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology	YES
4956736	27443269	AK	2	contributed to project conception, protocol development and project implementation planning	contributed to project conception, protocol development and project implementation planning	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
4956736	27443269	DA	2	also contributed to project implementation planning|contributed to data collection	also contributed to project implementation planning	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4956736	27443269	DA	2	also contributed to project implementation planning|contributed to data collection	contributed to data collection	Performed the experiments	Investigation	YES
4956736	27443269	DB	2	contributed to project conception, protocol development and project implementation planning	contributed to project conception, protocol development and project implementation planning	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
4956736	27443269	IA	2	also contributed to project implementation planning	also contributed to project implementation planning	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4956736	27443269	JR	2	contributed to project conception, protocol development and project implementation planning|contributed to data analysis	contributed to project conception, protocol development and project implementation planning	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
4956736	27443269	JR	2	contributed to project conception, protocol development and project implementation planning|contributed to data analysis	contributed to data analysis	Analyzed the data	Formal analysis	YES
4956736	27443269	SAG	2	contributed to data analysis|drafted and finalized the article with review from all authors	contributed to data analysis	Analyzed the data	Formal analysis	YES
4956736	27443269	SAG	2	contributed to data analysis|drafted and finalized the article with review from all authors	drafted and finalized the article with review from all authors	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4956736	27443269	SD	2	contributed to project conception, protocol development and project implementation planning|contributed to data collection	contributed to project conception, protocol development and project implementation planning	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
4956736	27443269	SD	2	contributed to project conception, protocol development and project implementation planning|contributed to data collection	contributed to data collection	Performed the experiments	Investigation	YES
4956736	27443269	SG	2	contributed to project conception, protocol development and project implementation planning|contributed to data analysis|drafted and finalized the article with review from all authors	contributed to project conception, protocol development and project implementation planning	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
4956736	27443269	SG	2	contributed to project conception, protocol development and project implementation planning|contributed to data analysis|drafted and finalized the article with review from all authors	contributed to data analysis	Analyzed the data	Formal analysis	YES
4956736	27443269	SG	2	contributed to project conception, protocol development and project implementation planning|contributed to data analysis|drafted and finalized the article with review from all authors	drafted and finalized the article with review from all authors	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4956736	27443269	SKa	2	contributed to project conception, protocol development and project implementation planning	contributed to project conception, protocol development and project implementation planning	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
4956736	27443269	SKo	2	contributed to project conception, protocol development and project implementation planning|contributed to data collection	contributed to project conception, protocol development and project implementation planning	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
4956736	27443269	SKo	2	contributed to project conception, protocol development and project implementation planning|contributed to data collection	contributed to data collection	Performed the experiments	Investigation	YES
5314461	28209133	All authors	PLoS52	provided essential contributions to the interpretation of the data and all authors revised the manuscript critically for intellectual content|gave final approval to the version of the manuscript to be published and agreed to be accountable for all aspects of the work	provided essential contributions to the interpretation of the data and all authors revised the manuscript critically for intellectual content	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
5314461	28209133	All authors	PLoS52	provided essential contributions to the interpretation of the data and all authors revised the manuscript critically for intellectual content|gave final approval to the version of the manuscript to be published and agreed to be accountable for all aspects of the work	gave final approval to the version of the manuscript to be published and agreed to be accountable for all aspects of the work	-	-	NO
5314461	28209133	ES	PLoS52	generated rna seq data	generated rna seq data	Performed the experiments	Investigation	YES
5314461	28209133	JG	PLoS52	conceived the study, generated rna seq data, analyzed the data and drafted the manuscript	conceived the study, generated rna seq data, analyzed the data and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
5314461	28209133	KG	PLoS52	analyzed the data and drafted the manuscript	analyzed the data and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5314461	28209133	MS	PLoS52	performed the genome annotation and transcript predictions	performed the genome annotation and transcript predictions	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5314461	28209133	RH	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5314461	28209133	SR	PLoS52	generated the p	generated the p	Performed the experiments	Investigation	YES
5314461	28209133	TW	PLoS52	performed the genome annotation and transcript predictions	performed the genome annotation and transcript predictions	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5789560	29416209	FF	2	contributed to analysis and interpretation of data, and assisted in the preparation of the manuscript	contributed to analysis and interpretation of data, and assisted in the preparation of the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
5789560	29416209	HY	2	contributed to analysis and interpretation of data, and assisted in the preparation of the manuscript	contributed to analysis and interpretation of data, and assisted in the preparation of the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
5789560	29416209	KM	2	designed the study, and wrote the initial draft of the manuscript	designed the study, and wrote the initial draft of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5789560	29416209	MS	2	contributed to analysis and interpretation of data, and assisted in the preparation of the manuscript	contributed to analysis and interpretation of data, and assisted in the preparation of the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
5789560	29416209	SHY	2	contributed to analysis and interpretation of data, and assisted in the preparation of the manuscript	contributed to analysis and interpretation of data, and assisted in the preparation of the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
5789560	29416209	TO	2	designed the study, and wrote the initial draft of the manuscript	designed the study, and wrote the initial draft of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5789560	29416209	TY	2	designed the study, and wrote the initial draft of the manuscript	designed the study, and wrote the initial draft of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
6165518	30158484	A.C.G.E.	CRediT	Conceptualization|Data curation|Investigation|Supervision|Writing--review and editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6165518	30158484	A.C.G.E.	CRediT	Conceptualization|Data curation|Investigation|Supervision|Writing--review and editing	Data curation	Analyzed the data	Data curation	YES
6165518	30158484	A.C.G.E.	CRediT	Conceptualization|Data curation|Investigation|Supervision|Writing--review and editing	Investigation	Performed the experiments	Investigation	YES
6165518	30158484	A.C.G.E.	CRediT	Conceptualization|Data curation|Investigation|Supervision|Writing--review and editing	Supervision	-	Supervision	YES
6165518	30158484	A.C.G.E.	CRediT	Conceptualization|Data curation|Investigation|Supervision|Writing--review and editing	Writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6165518	30158484	B.J.F.v.d.B.	CRediT	Conceptualization|Data curation|Investigation|Supervision|Writing--review and editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6165518	30158484	B.J.F.v.d.B.	CRediT	Conceptualization|Data curation|Investigation|Supervision|Writing--review and editing	Data curation	Analyzed the data	Data curation	YES
6165518	30158484	B.J.F.v.d.B.	CRediT	Conceptualization|Data curation|Investigation|Supervision|Writing--review and editing	Investigation	Performed the experiments	Investigation	YES
6165518	30158484	B.J.F.v.d.B.	CRediT	Conceptualization|Data curation|Investigation|Supervision|Writing--review and editing	Supervision	-	Supervision	YES
6165518	30158484	B.J.F.v.d.B.	CRediT	Conceptualization|Data curation|Investigation|Supervision|Writing--review and editing	Writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6165518	30158484	C.L.B.	CRediT	Conceptualization|Data curation|Formal analysis|Investigation|Project administration|Writing--original draft	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6165518	30158484	C.L.B.	CRediT	Conceptualization|Data curation|Formal analysis|Investigation|Project administration|Writing--original draft	Data curation	Analyzed the data	Data curation	YES
6165518	30158484	C.L.B.	CRediT	Conceptualization|Data curation|Formal analysis|Investigation|Project administration|Writing--original draft	Formal analysis	Analyzed the data	Formal analysis	YES
6165518	30158484	C.L.B.	CRediT	Conceptualization|Data curation|Formal analysis|Investigation|Project administration|Writing--original draft	Investigation	Performed the experiments	Investigation	YES
6165518	30158484	C.L.B.	CRediT	Conceptualization|Data curation|Formal analysis|Investigation|Project administration|Writing--original draft	Project administration	-	Project administration	YES
6165518	30158484	C.L.B.	CRediT	Conceptualization|Data curation|Formal analysis|Investigation|Project administration|Writing--original draft	Writing--original draft	Wrote the paper	Writing - Original Draft	YES
6165518	30158484	H.G.	CRediT	Conceptualization|Data curation|Investigation|Supervision|Writing--review and editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6165518	30158484	H.G.	CRediT	Conceptualization|Data curation|Investigation|Supervision|Writing--review and editing	Data curation	Analyzed the data	Data curation	YES
6165518	30158484	H.G.	CRediT	Conceptualization|Data curation|Investigation|Supervision|Writing--review and editing	Investigation	Performed the experiments	Investigation	YES
6165518	30158484	H.G.	CRediT	Conceptualization|Data curation|Investigation|Supervision|Writing--review and editing	Supervision	-	Supervision	YES
6165518	30158484	H.G.	CRediT	Conceptualization|Data curation|Investigation|Supervision|Writing--review and editing	Writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6165518	30158484	M.L.B.	CRediT	Conceptualization|Data curation|Investigation|Supervision|Writing--review and editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6165518	30158484	M.L.B.	CRediT	Conceptualization|Data curation|Investigation|Supervision|Writing--review and editing	Data curation	Analyzed the data	Data curation	YES
6165518	30158484	M.L.B.	CRediT	Conceptualization|Data curation|Investigation|Supervision|Writing--review and editing	Investigation	Performed the experiments	Investigation	YES
6165518	30158484	M.L.B.	CRediT	Conceptualization|Data curation|Investigation|Supervision|Writing--review and editing	Supervision	-	Supervision	YES
6165518	30158484	M.L.B.	CRediT	Conceptualization|Data curation|Investigation|Supervision|Writing--review and editing	Writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
4406499	25902063	FG	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Discussed data and analysis|Discussed and revised manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4406499	25902063	FG	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Discussed data and analysis|Discussed and revised manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4406499	25902063	FG	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Discussed data and analysis|Discussed and revised manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406499	25902063	FG	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Discussed data and analysis|Discussed and revised manuscript	Discussed data and analysis	Analyzed the data	Formal analysis	YES
4406499	25902063	FG	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Discussed data and analysis|Discussed and revised manuscript	Discussed and revised manuscript	Wrote the paper	Writing - Review & Editing	YES
4406499	25902063	MG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Collected samples|Discussed data and analysis|Discussed and revised manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406499	25902063	MG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Collected samples|Discussed data and analysis|Discussed and revised manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406499	25902063	MG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Collected samples|Discussed data and analysis|Discussed and revised manuscript	Collected samples	Performed the experiments	Investigation	YES
4406499	25902063	MG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Collected samples|Discussed data and analysis|Discussed and revised manuscript	Discussed data and analysis	Analyzed the data	Formal analysis	YES
4406499	25902063	MG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Collected samples|Discussed data and analysis|Discussed and revised manuscript	Discussed and revised manuscript	Wrote the paper	Writing - Review & Editing	YES
4406499	25902063	WEP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Collected samples|Discussed data and analysis|Discussed and revised manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406499	25902063	WEP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Collected samples|Discussed data and analysis|Discussed and revised manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406499	25902063	WEP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Collected samples|Discussed data and analysis|Discussed and revised manuscript	Collected samples	Performed the experiments	Investigation	YES
4406499	25902063	WEP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Collected samples|Discussed data and analysis|Discussed and revised manuscript	Discussed data and analysis	Analyzed the data	Formal analysis	YES
4406499	25902063	WEP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Collected samples|Discussed data and analysis|Discussed and revised manuscript	Discussed and revised manuscript	Wrote the paper	Writing - Review & Editing	YES
4956737	27443272	SK	2	wrote the first draft of the paper|collated their inputs and produced subsequent drafts of the paper	wrote the first draft of the paper	Wrote the paper	Writing - Original Draft	YES
4956737	27443272	SK	2	wrote the first draft of the paper|collated their inputs and produced subsequent drafts of the paper	collated their inputs and produced subsequent drafts of the paper	Wrote the paper	Writing - Original Draft	YES
5314462	28209138	BP	2	provided comments on the manuscript|were involved in the selection of the isolates|provided additional information about where the isolates were sampled	provided comments on the manuscript	-	-	NO
5314462	28209138	BP	2	provided comments on the manuscript|were involved in the selection of the isolates|provided additional information about where the isolates were sampled	were involved in the selection of the isolates	Performed the experiments	Investigation	YES
5314462	28209138	BP	2	provided comments on the manuscript|were involved in the selection of the isolates|provided additional information about where the isolates were sampled	provided additional information about where the isolates were sampled	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5314462	28209138	DC	2	provided comments on the manuscript|were involved in the selection of the isolates|were involved in the rea typing of the isolates	provided comments on the manuscript	-	-	NO
5314462	28209138	DC	2	provided comments on the manuscript|were involved in the selection of the isolates|were involved in the rea typing of the isolates	were involved in the selection of the isolates	Performed the experiments	Investigation	YES
5314462	28209138	DC	2	provided comments on the manuscript|were involved in the selection of the isolates|were involved in the rea typing of the isolates	were involved in the rea typing of the isolates	Performed the experiments	Investigation	YES
5314462	28209138	GdL	2	provided comments on the manuscript|were involved in the selection of the isolates|were involved in the rea typing of the isolates	provided comments on the manuscript	-	-	NO
5314462	28209138	GdL	2	provided comments on the manuscript|were involved in the selection of the isolates|were involved in the rea typing of the isolates	were involved in the selection of the isolates	Performed the experiments	Investigation	YES
5314462	28209138	GdL	2	provided comments on the manuscript|were involved in the selection of the isolates|were involved in the rea typing of the isolates	were involved in the rea typing of the isolates	Performed the experiments	Investigation	YES
5314462	28209138	JC	2	designed and implemented the analyses and wrote the manuscript	designed and implemented the analyses and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5314462	28209138	MN	2	provided comments on the manuscript|were involved in the selection of the isolates|provided additional information about where the isolates were sampled	provided comments on the manuscript	-	-	NO
5314462	28209138	MN	2	provided comments on the manuscript|were involved in the selection of the isolates|provided additional information about where the isolates were sampled	were involved in the selection of the isolates	Performed the experiments	Investigation	YES
5314462	28209138	MN	2	provided comments on the manuscript|were involved in the selection of the isolates|provided additional information about where the isolates were sampled	provided additional information about where the isolates were sampled	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5314462	28209138	MP-C	2	provided comments on the manuscript|were involved in the selection of the isolates|designed and advised on the implementation of the study|coordinated the sequencing of the isolates and conducted the additional vntr assays	provided comments on the manuscript	-	-	NO
5314462	28209138	MP-C	2	provided comments on the manuscript|were involved in the selection of the isolates|designed and advised on the implementation of the study|coordinated the sequencing of the isolates and conducted the additional vntr assays	were involved in the selection of the isolates	Performed the experiments	Investigation	YES
5314462	28209138	MP-C	2	provided comments on the manuscript|were involved in the selection of the isolates|designed and advised on the implementation of the study|coordinated the sequencing of the isolates and conducted the additional vntr assays	designed and advised on the implementation of the study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5314462	28209138	MP-C	2	provided comments on the manuscript|were involved in the selection of the isolates|designed and advised on the implementation of the study|coordinated the sequencing of the isolates and conducted the additional vntr assays	coordinated the sequencing of the isolates and conducted the additional vntr assays	Performed the experiments	Investigation|Project administration	YES
5314462	28209138	PL	2	provided comments on the manuscript|were involved in the selection of the isolates	provided comments on the manuscript	-	-	NO
5314462	28209138	PL	2	provided comments on the manuscript|were involved in the selection of the isolates	were involved in the selection of the isolates	Performed the experiments	Investigation	YES
5314462	28209138	RB	2	provided comments on the manuscript|provided technical advice about the phylogenetic analyses	provided comments on the manuscript	-	-	NO
5314462	28209138	RB	2	provided comments on the manuscript|provided technical advice about the phylogenetic analyses	provided technical advice about the phylogenetic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5314462	28209138	RK	2	provided comments on the manuscript|designed and advised on the implementation of the study	provided comments on the manuscript	-	-	NO
5314462	28209138	RK	2	provided comments on the manuscript|designed and advised on the implementation of the study	designed and advised on the implementation of the study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5314462	28209138	RZ	2	provided comments on the manuscript|advised on the design and implementation of the analyses	provided comments on the manuscript	-	-	NO
5314462	28209138	RZ	2	provided comments on the manuscript|advised on the design and implementation of the analyses	advised on the design and implementation of the analyses	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5314462	28209138	SH	2	provided comments on the manuscript|provided sequenced isolates from the sanger institute	provided comments on the manuscript	-	-	NO
5314462	28209138	SH	2	provided comments on the manuscript|provided sequenced isolates from the sanger institute	provided sequenced isolates from the sanger institute	Performed the experiments	Investigation	YES
5314462	28209138	SL	2	provided comments on the manuscript|provided technical advice about the phylogenetic analyses	provided comments on the manuscript	-	-	NO
5314462	28209138	SL	2	provided comments on the manuscript|provided technical advice about the phylogenetic analyses	provided technical advice about the phylogenetic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4406500	25901739	HMW	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4406500	25901739	HMW	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4406500	25901739	JML	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4406500	25901739	JML	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4406500	25901739	SY	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406500	25901739	YJJ	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406500	25901739	YJJ	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5559719	28861104	All authors	2	approve the version to be published|agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	approve the version to be published	-	-	NO
5559719	28861104	All authors	2	approve the version to be published|agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	-	-	NO
5559719	28861104	DX	2	revised it critically for important intellectual content	revised it critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5559719	28861104	LT	2	analyzed and interpretated the data for the work|wrote the manuscript	analyzed and interpretated the data for the work	Analyzed the data	Formal analysis	YES
5559719	28861104	LT	2	analyzed and interpretated the data for the work|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5559719	28861104	NY	2	planned and designed the research	planned and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5559719	28861104	TM	2	planned and designed the research|revised it critically for important intellectual content	planned and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5559719	28861104	TM	2	planned and designed the research|revised it critically for important intellectual content	revised it critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5559719	28861104	XF	2	analyzed and interpretated the data for the work	analyzed and interpretated the data for the work	Analyzed the data	Formal analysis	YES
5559719	28861104	XZ	2	revised it critically for important intellectual content	revised it critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5681335	29158895	Edoardo Raposio	7	study design and data analysis	study design and data analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5681335	29158895	Elisa Bellini	7	data collection and writing the manuscript	data collection and writing the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5681335	29158895	Michele P. Grieco	7	management of clinical cases	management of clinical cases	-	-	NO
6165543	30081557	B.S.	CRediT	Conceptualization|Investigation|Methodology|Project administration|Writing-original draft|Writing-review & editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6165543	30081557	B.S.	CRediT	Conceptualization|Investigation|Methodology|Project administration|Writing-original draft|Writing-review & editing	Investigation	Performed the experiments	Investigation	YES
6165543	30081557	B.S.	CRediT	Conceptualization|Investigation|Methodology|Project administration|Writing-original draft|Writing-review & editing	Methodology	Performed the experiments	Methodology	YES
6165543	30081557	B.S.	CRediT	Conceptualization|Investigation|Methodology|Project administration|Writing-original draft|Writing-review & editing	Project administration	-	Project administration	YES
6165543	30081557	B.S.	CRediT	Conceptualization|Investigation|Methodology|Project administration|Writing-original draft|Writing-review & editing	Writing-original draft	Wrote the paper	Writing - Original Draft	YES
6165543	30081557	B.S.	CRediT	Conceptualization|Investigation|Methodology|Project administration|Writing-original draft|Writing-review & editing	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6165543	30081557	D.D.	CRediT	Conceptualization|Funding acquisition|Methodology|Writing-review & editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6165543	30081557	D.D.	CRediT	Conceptualization|Funding acquisition|Methodology|Writing-review & editing	Funding acquisition	-	Funding acquisition	YES
6165543	30081557	D.D.	CRediT	Conceptualization|Funding acquisition|Methodology|Writing-review & editing	Methodology	Performed the experiments	Methodology	YES
6165543	30081557	D.D.	CRediT	Conceptualization|Funding acquisition|Methodology|Writing-review & editing	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6165543	30081557	I.f.K.	CRediT	Data curation|Formal analysis|Methodology|Writing-original draft|Writing-review & editing	Data curation	Analyzed the data	Data curation	YES
6165543	30081557	I.f.K.	CRediT	Data curation|Formal analysis|Methodology|Writing-original draft|Writing-review & editing	Formal analysis	Analyzed the data	Formal analysis	YES
6165543	30081557	I.f.K.	CRediT	Data curation|Formal analysis|Methodology|Writing-original draft|Writing-review & editing	Methodology	Performed the experiments	Methodology	YES
6165543	30081557	I.f.K.	CRediT	Data curation|Formal analysis|Methodology|Writing-original draft|Writing-review & editing	Writing-original draft	Wrote the paper	Writing - Original Draft	YES
6165543	30081557	I.f.K.	CRediT	Data curation|Formal analysis|Methodology|Writing-original draft|Writing-review & editing	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6165543	30081557	S.N.	CRediT	Conceptualization|Formal analysis|Funding acquisition|Investigation|Methodology|Project administration|Writing-original draft|Writing-review & editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6165543	30081557	S.N.	CRediT	Conceptualization|Formal analysis|Funding acquisition|Investigation|Methodology|Project administration|Writing-original draft|Writing-review & editing	Formal analysis	Analyzed the data	Formal analysis	YES
6165543	30081557	S.N.	CRediT	Conceptualization|Formal analysis|Funding acquisition|Investigation|Methodology|Project administration|Writing-original draft|Writing-review & editing	Funding acquisition	-	Funding acquisition	YES
6165543	30081557	S.N.	CRediT	Conceptualization|Formal analysis|Funding acquisition|Investigation|Methodology|Project administration|Writing-original draft|Writing-review & editing	Investigation	Performed the experiments	Investigation	YES
6165543	30081557	S.N.	CRediT	Conceptualization|Formal analysis|Funding acquisition|Investigation|Methodology|Project administration|Writing-original draft|Writing-review & editing	Methodology	Performed the experiments	Methodology	YES
6165543	30081557	S.N.	CRediT	Conceptualization|Formal analysis|Funding acquisition|Investigation|Methodology|Project administration|Writing-original draft|Writing-review & editing	Project administration	-	Project administration	YES
6165543	30081557	S.N.	CRediT	Conceptualization|Formal analysis|Funding acquisition|Investigation|Methodology|Project administration|Writing-original draft|Writing-review & editing	Writing-original draft	Wrote the paper	Writing - Original Draft	YES
6165543	30081557	S.N.	CRediT	Conceptualization|Formal analysis|Funding acquisition|Investigation|Methodology|Project administration|Writing-original draft|Writing-review & editing	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
5789566	29416216	KC	1	Conception and design|Statistical analysis|Writing of the manuscript|Interpretation of study results and proofreading of the manuscript	Conception and design	Conceived and designed the experiments	Conceptualization	YES
5789566	29416216	KC	1	Conception and design|Statistical analysis|Writing of the manuscript|Interpretation of study results and proofreading of the manuscript	Statistical analysis	Analyzed the data	Formal analysis	YES
5789566	29416216	KC	1	Conception and design|Statistical analysis|Writing of the manuscript|Interpretation of study results and proofreading of the manuscript	Writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5789566	29416216	KC	1	Conception and design|Statistical analysis|Writing of the manuscript|Interpretation of study results and proofreading of the manuscript	Interpretation of study results and proofreading of the manuscript	Analyzed the data	Formal analysis	YES
5789566	29416216	SB	1	Interpretation of study results and proofreading of the manuscript	Interpretation of study results and proofreading of the manuscript	Analyzed the data	Formal analysis	YES
5789566	29416216	SP	1	Conception and design|Statistical analysis|Writing of the manuscript|Interpretation of study results and proofreading of the manuscript	Conception and design	Conceived and designed the experiments	Conceptualization	YES
5789566	29416216	SP	1	Conception and design|Statistical analysis|Writing of the manuscript|Interpretation of study results and proofreading of the manuscript	Statistical analysis	Analyzed the data	Formal analysis	YES
5789566	29416216	SP	1	Conception and design|Statistical analysis|Writing of the manuscript|Interpretation of study results and proofreading of the manuscript	Writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5789566	29416216	SP	1	Conception and design|Statistical analysis|Writing of the manuscript|Interpretation of study results and proofreading of the manuscript	Interpretation of study results and proofreading of the manuscript	Analyzed the data	Formal analysis	YES
5789566	29416216	SY	1	Interpretation of study results and proofreading of the manuscript	Interpretation of study results and proofreading of the manuscript	Analyzed the data	Formal analysis	YES
5789566	29416216	WU	1	Interpretation of study results and proofreading of the manuscript	Interpretation of study results and proofreading of the manuscript	Analyzed the data	Formal analysis	YES
4956738	27443275	NNB	2	contributed sections to the first draft of the manuscript	contributed sections to the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
4956738	27443275	NR	2	contributed sections to the first draft of the manuscript	contributed sections to the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
4956738	27443275	WT	2	contributed to the synopsis of the studies introduced in the manuscript	contributed to the synopsis of the studies introduced in the manuscript	-	-	NO
5694962	29188051	Edoardo Raposio	7	study design and data analysis	study design and data analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5694962	29188051	Elisa Bellini	7	data collection and writing the manuscript	data collection and writing the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5694962	29188051	Michele P. Grieco	7	management of clinical cases	management of clinical cases	-	-	NO
4406515	25901350	F. Beissner	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406515	25901350	F. Beissner	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406515	25901350	F. Beissner	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406515	25901350	F. Brunner	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4406515	25901350	F. Brunner	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4406515	25901350	KM	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406515	25901350	MF	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4406515	25901350	MF	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4406515	25901350	TK	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406515	25901350	VN	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5559735	28861097	H. Both	2	authors jointly edited successive versions and approved it for publication	authors jointly edited successive versions and approved it for publication	Wrote the paper	Writing - Review & Editing	YES
5789567	29416222	E.B.	2	revised it critically and gave nal approval of the version to be submitted	revised it critically and gave nal approval of the version to be submitted	Wrote the paper	Writing - Review & Editing	YES
5789567	29416222	N.N.	2	revised it critically and gave nal approval of the version to be submitted	revised it critically and gave nal approval of the version to be submitted	Wrote the paper	Writing - Review & Editing	YES
5789567	29416222	Z.B.	2	revised it critically and gave nal approval of the version to be submitted	revised it critically and gave nal approval of the version to be submitted	Wrote the paper	Writing - Review & Editing	YES
5314613	28209124	All the authors	2	has given their consent to publish this study	has given their consent to publish this study	-	-	NO
5314613	28209124	C-L.W.	2	contributed to data analysis, interpretation of the data, writing and revision of the manuscript	contributed to data analysis, interpretation of the data, writing and revision of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5314613	28209124	K.W.	2	contributed to design and implementation of the project and revision of the manuscript	contributed to design and implementation of the project and revision of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
5314613	28209124	Y.S.	2	contributed to metabolomics data processing, analysis and revision of the manuscript	contributed to metabolomics data processing, analysis and revision of the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Data curation|Formal analysis|Resources|Writing - Review & Editing	YES
5709339	29204274	Edoardo Raposio	7	Data collection and writing	Data collection and writing	Performed the experiments|Wrote the paper	Investigation	YES
5709339	29204274	Rosagemma Ciliberti	7	Study design	Study design	Conceived and designed the experiments	Methodology	YES
4956739	27443274	BHW	2	revised and finalized this manuscript	revised and finalized this manuscript	Wrote the paper	Writing - Review & Editing	YES
4956739	27443274	GW	2	contributed data, reviewed and commented on this manuscript	contributed data, reviewed and commented on this manuscript	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Review & Editing	YES
4956739	27443274	SG	2	conceived and wrote the first draft of the manuscript|revised and finalized this manuscript	conceived and wrote the first draft of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4956739	27443274	SG	2	conceived and wrote the first draft of the manuscript|revised and finalized this manuscript	revised and finalized this manuscript	Wrote the paper	Writing - Review & Editing	YES
4956739	27443274	SK	2	contributed data, reviewed and commented on this manuscript	contributed data, reviewed and commented on this manuscript	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Review & Editing	YES
5789568	29416214	Goran Dimitrov	7	He approved the final version of the completed article	He approved the final version of the completed article	-	-	NO
5789568	29416214	Irena Aleksioska Papestiev	7	Designed the text for the first time, collected data and put everything together in its final form. esna Chibisheva: Collected and analyzed the collected data. Helped with text editing	Designed the text for the first time, collected data and put everything together in its final form. esna Chibisheva: Collected and analyzed the collected data. Helped with text editing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
5789568	29416214	Megi Micevska	7	Did all the laboratory work, collected and interpreted the results	Did all the laboratory work, collected and interpreted the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6306704	30241421	D.O.	CRediT	Conceptualization|Supervision|Project administration	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6306704	30241421	D.O.	CRediT	Conceptualization|Supervision|Project administration	Supervision	-	Supervision	YES
6306704	30241421	D.O.	CRediT	Conceptualization|Supervision|Project administration	Project administration	-	Project administration	YES
6306704	30241421	G.C.	CRediT	Methodology|Writing-review & Editing|Funding acquisition	Methodology	Performed the experiments	Methodology	YES
6306704	30241421	G.C.	CRediT	Methodology|Writing-review & Editing|Funding acquisition	Writing-review & Editing	Wrote the paper	Writing - Review & Editing	YES
6306704	30241421	G.C.	CRediT	Methodology|Writing-review & Editing|Funding acquisition	Funding acquisition	-	Funding acquisition	YES
6306704	30241421	H.H.	CRediT	Validation|Writing-review & Editing	Validation	Performed the experiments	Validation	YES
6306704	30241421	H.H.	CRediT	Validation|Writing-review & Editing	Writing-review & Editing	Wrote the paper	Writing - Review & Editing	YES
6306704	30241421	H.Z.	CRediT	Conceptualization|Validation|Formal analysis|Writing-original draft preparation|Visualization	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6306704	30241421	H.Z.	CRediT	Conceptualization|Validation|Formal analysis|Writing-original draft preparation|Visualization	Validation	Performed the experiments	Validation	YES
6306704	30241421	H.Z.	CRediT	Conceptualization|Validation|Formal analysis|Writing-original draft preparation|Visualization	Formal analysis	Analyzed the data	Formal analysis	YES
6306704	30241421	H.Z.	CRediT	Conceptualization|Validation|Formal analysis|Writing-original draft preparation|Visualization	Writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
6306704	30241421	H.Z.	CRediT	Conceptualization|Validation|Formal analysis|Writing-original draft preparation|Visualization	Visualization	Analyzed the data	Visualization	YES
6306704	30241421	W.Z.	CRediT	Conceptualization|Methodology|Formal analysis|Investigation|Writing-original draft preparation|Visualization	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6306704	30241421	W.Z.	CRediT	Conceptualization|Methodology|Formal analysis|Investigation|Writing-original draft preparation|Visualization	Methodology	Performed the experiments	Methodology	YES
6306704	30241421	W.Z.	CRediT	Conceptualization|Methodology|Formal analysis|Investigation|Writing-original draft preparation|Visualization	Formal analysis	Analyzed the data	Formal analysis	YES
6306704	30241421	W.Z.	CRediT	Conceptualization|Methodology|Formal analysis|Investigation|Writing-original draft preparation|Visualization	Investigation	Performed the experiments	Investigation	YES
6306704	30241421	W.Z.	CRediT	Conceptualization|Methodology|Formal analysis|Investigation|Writing-original draft preparation|Visualization	Writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
6306704	30241421	W.Z.	CRediT	Conceptualization|Methodology|Formal analysis|Investigation|Writing-original draft preparation|Visualization	Visualization	Analyzed the data	Visualization	YES
6306704	30241421	Y.H.	CRediT	Methodology|Writing-review & Editing	Methodology	Performed the experiments	Methodology	YES
6306704	30241421	Y.H.	CRediT	Methodology|Writing-review & Editing	Writing-review & Editing	Wrote the paper	Writing - Review & Editing	YES
6306704	30241421	Y.W.	CRediT	Investigation|Writing-review & Editing	Investigation	Performed the experiments	Investigation	YES
6306704	30241421	Y.W.	CRediT	Investigation|Writing-review & Editing	Writing-review & Editing	Wrote the paper	Writing - Review & Editing	YES
4499381	26221610	Rui Shi	2	contributed equally to this work	contributed equally to this work	-	-	NO
4499381	26221610	Xin Zhou	2	contributed equally to this work	contributed equally to this work	-	-	NO
5559850	28861101	CL	PLoS52	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5559850	28861101	DL	PLoS52	conceived and designed the experiments|analyzed the data|wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5559850	28861101	DL	PLoS52	conceived and designed the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5559850	28861101	DL	PLoS52	conceived and designed the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5559850	28861101	SL	PLoS52	conceived and designed the experiments|carried out the experiments|analyzed the data|wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5559850	28861101	SL	PLoS52	conceived and designed the experiments|carried out the experiments|analyzed the data|wrote the manuscript	carried out the experiments	Performed the experiments	Investigation	YES
5559850	28861101	SL	PLoS52	conceived and designed the experiments|carried out the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5559850	28861101	SL	PLoS52	conceived and designed the experiments|carried out the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5559850	28861101	YZ	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5559850	28861101	ZZ	PLoS52	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
4814723	27099640	Hardy Christoffersen	1	Research design and collection of data	Research design and collection of data	Conceived and designed the experiments|Performed the experiments	Investigation	YES
4814723	27099640	Niels Krarup	1	Research design and collection of data|Wrote or contributed to the writing of the manuscript	Research design and collection of data	Conceived and designed the experiments|Performed the experiments	Investigation	YES
4814723	27099640	Niels Krarup	1	Research design and collection of data|Wrote or contributed to the writing of the manuscript	Wrote or contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
4814723	27099640	Simon Limbrecht Mogensen	1	Research design and collection of data|Wrote or contributed to the writing of the manuscript	Research design and collection of data	Conceived and designed the experiments|Performed the experiments	Investigation	YES
4814723	27099640	Simon Limbrecht Mogensen	1	Research design and collection of data|Wrote or contributed to the writing of the manuscript	Wrote or contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
4814723	27099640	Thomas Jakobsen	1	Research design and collection of data|Wrote or contributed to the writing of the manuscript	Research design and collection of data	Conceived and designed the experiments|Performed the experiments	Investigation	YES
4814723	27099640	Thomas Jakobsen	1	Research design and collection of data|Wrote or contributed to the writing of the manuscript	Wrote or contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
4406518	25902355	AG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4406518	25902355	AH	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4406518	25902355	AH	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4406518	25902355	AVD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406518	25902355	AVD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406518	25902355	AVD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406518	25902355	CAG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406518	25902355	CAG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406518	25902355	CAG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406518	25902355	CAG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406518	25902355	FP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4406518	25902355	HD	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406518	25902355	HD	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406518	25902355	HD	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406518	25902355	JMS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4406518	25902355	JMS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4406518	25902355	LA	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406518	25902355	LA	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406518	25902355	LA	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406518	25902355	M. Carriere	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406518	25902355	M. Carriere	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406518	25902355	M. Carriere	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406518	25902355	M. Chevallet	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406518	25902355	M. Chevallet	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406518	25902355	M. Chevallet	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406518	25902355	NH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406518	25902355	NH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406518	25902355	NH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406518	25902355	ST	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406518	25902355	ST	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406518	25902355	ST	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406518	25902355	TR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406518	25902355	TR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406518	25902355	TR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406518	25902355	TR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406518	25902355	VCF	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5714380	29225822	BG	2	contributed to writing the paper	contributed to writing the paper	Wrote the paper	Writing - Original Draft	YES
5714380	29225822	KK	2	contributed to writing the paper	contributed to writing the paper	Wrote the paper	Writing - Original Draft	YES
5714380	29225822	KW	2	contributed to writing the paper	contributed to writing the paper	Wrote the paper	Writing - Original Draft	YES
5714380	29225822	LK	2	contributed to writing the paper	contributed to writing the paper	Wrote the paper	Writing - Original Draft	YES
6306706	30304772	G.O.	2	reviewed the literature, wrote the first draft, and coordinated the production of the manuscript	reviewed the literature, wrote the first draft, and coordinated the production of the manuscript	Wrote the paper	Formal analysis|Project administration|Writing - Original Draft|Writing - Review & Editing	YES
6306706	30304772	L.A.	2	reviewed the literature, wrote the first draft, and coordinated the production of the manuscript	reviewed the literature, wrote the first draft, and coordinated the production of the manuscript	Wrote the paper	Formal analysis|Project administration|Writing - Original Draft|Writing - Review & Editing	YES
5789569	29416213	All authors	2	had significant contributions to all aspects of this research project	had significant contributions to all aspects of this research project	-	-	NO
5314637	28212611	AMF	2	performed the experimental work and carried out the bioinformatic data analysis	performed the experimental work and carried out the bioinformatic data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5314637	28212611	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5314637	28212611	EJ	2	contributed for the statistical analysis	contributed for the statistical analysis	Analyzed the data	Formal analysis	YES
5314637	28212611	HRM	2	planning and execution	planning and execution	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5314637	28212611	IP	2	contributed for the tassel software analysis	contributed for the tassel software analysis	Contributed reagents/materials/analysis tools	Software	YES
5314637	28212611	MFD	2	contributed for the research planning, funding, discussion and paper writing	contributed for the research planning, funding, discussion and paper writing	Conceived and designed the experiments|Wrote the paper	Funding acquisition|Methodology	YES
5314637	28212611	MMO	2	contributed for the research planning, funding, discussion and paper writing	contributed for the research planning, funding, discussion and paper writing	Conceived and designed the experiments|Wrote the paper	Funding acquisition|Methodology	YES
5314637	28212611	OG	2	contributed for the statistical analysis	contributed for the statistical analysis	Analyzed the data	Formal analysis	YES
5314637	28212611	PR	2	contributed for ht-uhplc-ms the planning and execution	contributed for ht-uhplc-ms the planning and execution	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5314637	28212611	RL	2	contributed for the research planning, funding, discussion and paper writing	contributed for the research planning, funding, discussion and paper writing	Conceived and designed the experiments|Wrote the paper	Funding acquisition|Methodology	YES
5314637	28212611	SG	2	contributed for the research planning, funding, discussion and paper writing	contributed for the research planning, funding, discussion and paper writing	Conceived and designed the experiments|Wrote the paper	Funding acquisition|Methodology	YES
5725204	29255602	All authors	2	contributed to and approved the final version of the manuscript	contributed to and approved the final version of the manuscript	-	-	NO
5725204	29255602	ZS	2	conceived the topic	conceived the topic	Conceived and designed the experiments	Conceptualization	YES
5562673	28861094	AT	2	all made a substantial, direct and intellectual contribution to the work, and approved it for publication	all made a substantial, direct and intellectual contribution to the work, and approved it for publication	-	-	NO
5562673	28861094	CR	2	designed the figure and the table|all made a substantial, direct and intellectual contribution to the work, and approved it for publication	designed the figure and the table	Conceived and designed the experiments	Visualization	YES
5562673	28861094	CR	2	designed the figure and the table|all made a substantial, direct and intellectual contribution to the work, and approved it for publication	all made a substantial, direct and intellectual contribution to the work, and approved it for publication	-	-	NO
5562673	28861094	PJ	2	all made a substantial, direct and intellectual contribution to the work, and approved it for publication	all made a substantial, direct and intellectual contribution to the work, and approved it for publication	-	-	NO
5562673	28861094	SG	2	all made a substantial, direct and intellectual contribution to the work, and approved it for publication	all made a substantial, direct and intellectual contribution to the work, and approved it for publication	-	-	NO
5562673	28861094	The authors	2	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	Performed the experiments	Investigation	YES
5562673	28861094	WM	2	all made a substantial, direct and intellectual contribution to the work, and approved it for publication	all made a substantial, direct and intellectual contribution to the work, and approved it for publication	-	-	NO
4406519	25902317	FS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4406519	25902317	FS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406519	25902317	KTW	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406519	25902317	KTW	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406519	25902317	MN	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4406519	25902317	MN	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406519	25902317	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406519	25902317	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406519	25902317	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406519	25902317	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406519	25902317	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406519	25902317	NS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4406519	25902317	NS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
3835626	24298389	Alemtsehay Mekonnen	2	contributed in data entry, analysis and interpretation of the findings and drafting and writing of the paper	contributed in data entry, analysis and interpretation of the findings and drafting and writing of the paper	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Data curation|Formal analysis|Resources|Writing - Original Draft	YES
3835626	24298389	Gedefaw Abeje	2	supervised the data collection, developed the questionnaire, contributed to the interpretation of the findings, and the drafting and writing of the paper	supervised the data collection, developed the questionnaire, contributed to the interpretation of the findings, and the drafting and writing of the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Supervision|Writing - Original Draft	YES
3835626	24298389	Muluken Azage	2	designed the study, developed the questionnaire, trained data collectors, supervised the data collection, analyzed the data, and wrote the paper	designed the study, developed the questionnaire, trained data collectors, supervised the data collection, analyzed the data, and wrote the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Supervision|Writing - Original Draft	YES
5789570	29416217	Ahmad Saeedi	2	considered and aimed, the study and drafted the final manuscript and conceived of the study, participated in disseminating and, collecting the survey	considered and aimed, the study and drafted the final manuscript and conceived of the study, participated in disseminating and, collecting the survey	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5789570	29416217	All authors	2	read, and approved of the final manuscript	read, and approved of the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5789570	29416217	Mahyar Salavati	2	considered and aimed, the study and drafted the final manuscript and conceived of the study, participated in disseminating and, collecting the survey	considered and aimed, the study and drafted the final manuscript and conceived of the study, participated in disseminating and, collecting the survey	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5789570	29416217	Masoud Gharib	2	considered and aimed, the study and drafted the final manuscript and conceived of the study, participated in disseminating and, collecting the survey	considered and aimed, the study and drafted the final manuscript and conceived of the study, participated in disseminating and, collecting the survey	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5789570	29416217	Roshanak Vameghi	2	considered and aimed, the study and drafted the final manuscript and conceived of the study, participated in disseminating and, collecting the survey	considered and aimed, the study and drafted the final manuscript and conceived of the study, participated in disseminating and, collecting the survey	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5789570	29416217	Seyed Ali Hosseini	2	considered and aimed, the study and drafted the final manuscript and conceived of the study, participated in disseminating and, collecting the survey	considered and aimed, the study and drafted the final manuscript and conceived of the study, participated in disseminating and, collecting the survey	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
4499382	26221595	Metzinger-Le Meuth	2	contributed equally to this work	contributed equally to this work	-	-	NO
5314683	28209181	EG	PLoS5	Interpretation of data and revised the paper	Interpretation of data and revised the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5314683	28209181	JQ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
5314683	28209181	JQ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5314683	28209181	JQ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5314683	28209181	SM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5314683	28209181	SZ	PLoS5	Interpretation of data and revised the paper	Interpretation of data and revised the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5314683	28209181	XY	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5314683	28209181	ZZ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5314683	28209181	ZZ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
6306714	30282930	All authors	2	participated in the concept, design of the methodology, recruitment, data collection, analysis, and interpretation of results, as well as the preparation of this paper	participated in the concept, design of the methodology, recruitment, data collection, analysis, and interpretation of results, as well as the preparation of this paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation|Methodology	YES
4406520	25902197	KMH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Obtained funding	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406520	25902197	KMH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Obtained funding	Performed the experiments	Performed the experiments	Investigation	YES
4406520	25902197	KMH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Obtained funding	Analyzed the data	Analyzed the data	Formal analysis	YES
4406520	25902197	KMH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Obtained funding	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406520	25902197	KMH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Obtained funding	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406520	25902197	KMH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Obtained funding	Obtained funding	-	Funding acquisition	YES
4406520	25902197	MB	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406520	25902197	MB	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406520	25902197	MB	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406520	25902197	SR	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Obtained funding	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406520	25902197	SR	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Obtained funding	Performed the experiments	Performed the experiments	Investigation	YES
4406520	25902197	SR	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Obtained funding	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406520	25902197	SR	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Obtained funding	Obtained funding	-	Funding acquisition	YES
4406520	25902197	TSW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406520	25902197	TSW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406520	25902197	TSW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406520	25902197	TSW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5562691	28861106	EE	2	carried out all seed germination-related work, including data analysis and artwork preparation	carried out all seed germination-related work, including data analysis and artwork preparation	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
5562691	28861106	JB	2	performed the hplc experiments for sugar fractionation, identification, and quantification	performed the hplc experiments for sugar fractionation, identification, and quantification	Performed the experiments	Investigation	YES
5562691	28861106	MA	2	performed biochemical assays and collaborated on the analysis of the data and the preparation of figures and tables	performed biochemical assays and collaborated on the analysis of the data and the preparation of figures and tables	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
5562691	28861106	ML	2	performed the hplc experiments for sugar fractionation, identification, and quantification	performed the hplc experiments for sugar fractionation, identification, and quantification	Performed the experiments	Investigation	YES
5562691	28861106	OV	2	participated in the design, general organization and supervision of the work, and in the interpretation of the results	participated in the design, general organization and supervision of the work, and in the interpretation of the results	Conceived and designed the experiments|Analyzed the data	Formal analysis|Supervision	YES
5562691	28861106	PS	2	carried out all seed germination-related work, including data analysis and artwork preparation	carried out all seed germination-related work, including data analysis and artwork preparation	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
5734825	29276586	A Sule	2	managed the patients, conceived and wrote up the article	managed the patients, conceived and wrote up the article	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
5734825	29276586	Dr Okolo	2	were involved in the management of the patients and agreed with the writeup	were involved in the management of the patients and agreed with the writeup	Performed the experiments|Wrote the paper	Investigation	YES
5734825	29276586	Dr Ralph	2	were involved in the management of the patients and agreed with the writeup	were involved in the management of the patients and agreed with the writeup	Performed the experiments|Wrote the paper	Investigation	YES
5734825	29276586	Prof Nzegwu	2	read and agreed with write up	read and agreed with write up	Wrote the paper	-	YES
5789571	29416218	All the authors	2	participated equally in the preparation of the manuscript, and have seen and agreed to the submission of article	participated equally in the preparation of the manuscript, and have seen and agreed to the submission of article	Wrote the paper	Writing - Original Draft	YES
5736856	29276585	Elham Sadat Banimostafavi	1	Data interpretation	Data interpretation	Analyzed the data	Formal analysis	YES
5736856	29276585	Hajar Ziaei Hezarjaribi	1	Data interpretation	Data interpretation	Analyzed the data	Formal analysis	YES
5736856	29276585	Mahdi Fakhar	1	Study concept|Data interpretation|Writing the paper	Study concept	Conceived and designed the experiments	Conceptualization	YES
5736856	29276585	Mahdi Fakhar	1	Study concept|Data interpretation|Writing the paper	Data interpretation	Analyzed the data	Formal analysis	YES
5736856	29276585	Mahdi Fakhar	1	Study concept|Data interpretation|Writing the paper	Writing the paper	Wrote the paper	Writing - Original Draft	YES
5736856	29276585	Masoud Soosaraei	1	Data collection	Data collection	Performed the experiments	Investigation	YES
5736856	29276585	Mastoid Soosaraei	1	Writing the paper	Writing the paper	Wrote the paper	Writing - Original Draft	YES
5736856	29276585	Shahriar Alizadeh	1	Data interpretation	Data interpretation	Analyzed the data	Formal analysis	YES
4499418	26221602	Hao Ding	2	equally contributed to this work	equally contributed to this work	-	-	NO
4499418	26221602	Zhihong Jian	2	equally contributed to this work	equally contributed to this work	-	-	NO
5789574	29416223	All	2	authos participated in each step of case report and gave final approval for publishing	authos participated in each step of case report and gave final approval for publishing	-	-	NO
5314692	28212602	JYC	2	conceived the idea, designed the database interface, and supervised the data content development, and wrote the manuscript|supervised the and drafted the manuscript under the	conceived the idea, designed the database interface, and supervised the data content development, and wrote the manuscript	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Software|Supervision|Writing - Original Draft	YES
5314692	28212602	JYC	2	conceived the idea, designed the database interface, and supervised the data content development, and wrote the manuscript|supervised the and drafted the manuscript under the	supervised the and drafted the manuscript under the	Wrote the paper	Supervision|Writing - Original Draft	YES
5314692	28212602	RP	2	integrated the data sets from various data sources, designed and implemented the database schema, developed the web site application, and drafted the manuscript under the	integrated the data sets from various data sources, designed and implemented the database schema, developed the web site application, and drafted the manuscript under the	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Software|Writing - Original Draft	YES
5314692	28212602	TN	2	performed the data coverage and quality evaluations, and helped strengthen the research methodology used in this study	performed the data coverage and quality evaluations, and helped strengthen the research methodology used in this study	Performed the experiments	Data curation|Methodology	YES
4406521	25901894	BW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4406521	25901894	CZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4406521	25901894	FW	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406521	25901894	FW	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406521	25901894	FW	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406521	25901894	FW	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406521	25901894	JL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4406521	25901894	KY	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4406521	25901894	WY	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406521	25901894	WY	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406521	25901894	YP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406521	25901894	YP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406521	25901894	YP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406521	25901894	YP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5562715	28861105	SZ	2	proposed the topic|collected the literature and critically assessed the information|wrote the manuscript	proposed the topic	Conceived and designed the experiments	Conceptualization	YES
5562715	28861105	SZ	2	proposed the topic|collected the literature and critically assessed the information|wrote the manuscript	collected the literature and critically assessed the information	Performed the experiments	Formal analysis|Investigation	YES
5562715	28861105	SZ	2	proposed the topic|collected the literature and critically assessed the information|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5562715	28861105	XL	2	collected the literature and critically assessed the information|wrote the manuscript	collected the literature and critically assessed the information	Performed the experiments	Formal analysis|Investigation	YES
5562715	28861105	XL	2	collected the literature and critically assessed the information|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5562715	28861105	YL	2	collected the literature and critically assessed the information	collected the literature and critically assessed the information	Performed the experiments	Formal analysis|Investigation	YES
5911162	29736107	Dr Asal	2	evaluated the radiologic findings	evaluated the radiologic findings	-	-	NO
5911162	29736107	Dr Aydin	2	performed the operation and designed the study|revised the final version of the paper	performed the operation and designed the study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5911162	29736107	Dr Aydin	2	performed the operation and designed the study|revised the final version of the paper	revised the final version of the paper	Wrote the paper	Writing - Review & Editing	YES
5911162	29736107	Dr Karaca	2	performed the operation and designed the study	performed the operation and designed the study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5911162	29736107	Dr Ozkan	2	performed the operation and designed the study	performed the operation and designed the study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5911162	29736107	Dr Sagsoz	2	revised the final version of the paper	revised the final version of the paper	Wrote the paper	Writing - Review & Editing	YES
5911162	29736107	Dr Sayan	2	performed the operation and designed the study|wrote the first draft of the paper|revised the final version of the paper	performed the operation and designed the study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5911162	29736107	Dr Sayan	2	performed the operation and designed the study|wrote the first draft of the paper|revised the final version of the paper	wrote the first draft of the paper	Wrote the paper	Writing - Original Draft	YES
5911162	29736107	Dr Sayan	2	performed the operation and designed the study|wrote the first draft of the paper|revised the final version of the paper	revised the final version of the paper	Wrote the paper	Writing - Review & Editing	YES
5911162	29736107	Dr Yeral	2	performed the operation and designed the study	performed the operation and designed the study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5751997	29321919	JB	2	devised and produced this manuscript	devised and produced this manuscript	Conceived and designed the experiments	Conceptualization	YES
6306739	30544554	H.D.B.	CRediT	Conceptualization|methodology|investigation|data curation|writing--original draft preparation|writing--review and editing|visualization|project administration	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6306739	30544554	H.D.B.	CRediT	Conceptualization|methodology|investigation|data curation|writing--original draft preparation|writing--review and editing|visualization|project administration	methodology	Performed the experiments	Methodology	YES
6306739	30544554	H.D.B.	CRediT	Conceptualization|methodology|investigation|data curation|writing--original draft preparation|writing--review and editing|visualization|project administration	investigation	Performed the experiments	Investigation	YES
6306739	30544554	H.D.B.	CRediT	Conceptualization|methodology|investigation|data curation|writing--original draft preparation|writing--review and editing|visualization|project administration	data curation	Analyzed the data	Data curation	YES
6306739	30544554	H.D.B.	CRediT	Conceptualization|methodology|investigation|data curation|writing--original draft preparation|writing--review and editing|visualization|project administration	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6306739	30544554	H.D.B.	CRediT	Conceptualization|methodology|investigation|data curation|writing--original draft preparation|writing--review and editing|visualization|project administration	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6306739	30544554	H.D.B.	CRediT	Conceptualization|methodology|investigation|data curation|writing--original draft preparation|writing--review and editing|visualization|project administration	visualization	Analyzed the data	Visualization	YES
6306739	30544554	H.D.B.	CRediT	Conceptualization|methodology|investigation|data curation|writing--original draft preparation|writing--review and editing|visualization|project administration	project administration	-	Project administration	YES
6306739	30544554	J.H.P.	CRediT	Conceptualization|methodology|writing--review and editing|supervision	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6306739	30544554	J.H.P.	CRediT	Conceptualization|methodology|writing--review and editing|supervision	methodology	Performed the experiments	Methodology	YES
6306739	30544554	J.H.P.	CRediT	Conceptualization|methodology|writing--review and editing|supervision	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6306739	30544554	J.H.P.	CRediT	Conceptualization|methodology|writing--review and editing|supervision	supervision	-	Supervision	YES
6306739	30544554	R.H.T.	CRediT	formal analysis|writing--review and editing	formal analysis	Analyzed the data	Formal analysis	YES
6306739	30544554	R.H.T.	CRediT	formal analysis|writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6306748	30445719	All authors	PLoS52	reviewed and approved the final draft of the paper	reviewed and approved the final draft of the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6306748	30445719	D.A.	PLoS52	analysed the data|wrote the initial draft	analysed the data	Analyzed the data	Formal analysis	YES
6306748	30445719	D.A.	PLoS52	analysed the data|wrote the initial draft	wrote the initial draft	Wrote the paper	Writing - Original Draft	YES
6306748	30445719	L.G.	PLoS52	conceived the study|analysed the data	conceived the study	Conceived and designed the experiments	Conceptualization	YES
6306748	30445719	L.G.	PLoS52	conceived the study|analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
6306748	30445719	S.B.G.	PLoS52	performed the data collection|analysed the data	performed the data collection	Performed the experiments	Investigation	YES
6306748	30445719	S.B.G.	PLoS52	performed the data collection|analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
6306748	30445719	T.M.	PLoS52	analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
5314710	28209125	AB	2	analysed ecological traits and was a major contributor in writing the manuscript|provided critical intellectual contributions to data analysis and to drafting and revising the manuscript	analysed ecological traits and was a major contributor in writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5314710	28209125	AB	2	analysed ecological traits and was a major contributor in writing the manuscript|provided critical intellectual contributions to data analysis and to drafting and revising the manuscript	provided critical intellectual contributions to data analysis and to drafting and revising the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5314710	28209125	IAK	2	conceived and planned the study, verified the round goby mitochondrial genome sequences, performed mitogenome length analyses, analysed and compared the control region sequences, analysed gene arrangements, wrote the manuscript and prepared the figures	conceived and planned the study, verified the round goby mitochondrial genome sequences, performed mitogenome length analyses, analysed and compared the control region sequences, analysed gene arrangements, wrote the manuscript and prepared the figures	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Validation|Visualization|Writing - Original Draft	YES
5314710	28209125	MAR	2	assembled and verified the round and sand goby mitochondrial genome sequences from next generation sequencing data|contributed to the writing of the manuscript	assembled and verified the round and sand goby mitochondrial genome sequences from next generation sequencing data	Performed the experiments	Investigation|Validation	YES
5314710	28209125	MAR	2	assembled and verified the round and sand goby mitochondrial genome sequences from next generation sequencing data|contributed to the writing of the manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5314710	28209125	MP	2	assembled and verified the round and sand goby mitochondrial genome sequences from next generation sequencing data|contributed to the writing of the manuscript	assembled and verified the round and sand goby mitochondrial genome sequences from next generation sequencing data	Performed the experiments	Investigation|Validation	YES
5314710	28209125	MP	2	assembled and verified the round and sand goby mitochondrial genome sequences from next generation sequencing data|contributed to the writing of the manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5314710	28209125	PBH	2	provided critical intellectual contributions to data analysis and to drafting and revising the manuscript	provided critical intellectual contributions to data analysis and to drafting and revising the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5314710	28209125	SS	2	assembled and verified the round and sand goby mitochondrial genome sequences from next generation sequencing data	assembled and verified the round and sand goby mitochondrial genome sequences from next generation sequencing data	Performed the experiments	Investigation|Validation	YES
5314710	28209125	SW	2	assembled and verified the round and sand goby mitochondrial genome sequences from next generation sequencing data	assembled and verified the round and sand goby mitochondrial genome sequences from next generation sequencing data	Performed the experiments	Investigation|Validation	YES
5314710	28209125	VEK	2	participated in planning the study, annotated the round and sand goby mitochondrial genomes, generated alignments, performed phylogenetic analyses, and was a major contributor in writing the manuscript	participated in planning the study, annotated the round and sand goby mitochondrial genomes, generated alignments, performed phylogenetic analyses, and was a major contributor in writing the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4406522	25901355	AM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406522	25901355	AM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406522	25901355	AM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406522	25901355	AP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Had input into developing the model and its programming	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406522	25901355	AP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Had input into developing the model and its programming	Performed the experiments	Performed the experiments	Investigation	YES
4406522	25901355	AP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Had input into developing the model and its programming	Analyzed the data	Analyzed the data	Formal analysis	YES
4406522	25901355	AP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Had input into developing the model and its programming	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406522	25901355	AP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Had input into developing the model and its programming	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406522	25901355	AP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Had input into developing the model and its programming	Had input into developing the model and its programming	Performed the experiments|Contributed reagents/materials/analysis tools	Methodology|Software	YES
4406522	25901355	CS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406522	25901355	CS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406522	25901355	CS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406522	25901355	FN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Had input into developing the model and its programming	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406522	25901355	FN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Had input into developing the model and its programming	Performed the experiments	Performed the experiments	Investigation	YES
4406522	25901355	FN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Had input into developing the model and its programming	Analyzed the data	Analyzed the data	Formal analysis	YES
4406522	25901355	FN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Had input into developing the model and its programming	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406522	25901355	FN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Had input into developing the model and its programming	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406522	25901355	FN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Had input into developing the model and its programming	Had input into developing the model and its programming	Performed the experiments|Contributed reagents/materials/analysis tools	Methodology|Software	YES
4406522	25901355	JL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406522	25901355	JL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406522	25901355	JL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406522	25901355	RL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406522	25901355	RL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406522	25901355	RL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406522	25901355	RS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406522	25901355	RS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406522	25901355	RS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406522	25901355	VC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Had input into developing the model and its programming	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406522	25901355	VC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Had input into developing the model and its programming	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406522	25901355	VC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Had input into developing the model and its programming	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406522	25901355	VC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Had input into developing the model and its programming	Had input into developing the model and its programming	Performed the experiments|Contributed reagents/materials/analysis tools	Methodology|Software	YES
4406522	25901355	VD	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406522	25901355	VD	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406522	25901355	VD	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5562723	28861096	CB	PLoS52	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5562723	28861096	JB	PLoS52	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5562723	28861096	LC	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5562723	28861096	RL	PLoS52	performed the experiments|analyzed all statistical data|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5562723	28861096	RL	PLoS52	performed the experiments|analyzed all statistical data|wrote the manuscript	analyzed all statistical data	Analyzed the data	Formal analysis	YES
5562723	28861096	RL	PLoS52	performed the experiments|analyzed all statistical data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5562723	28861096	RZ	PLoS52	analyzed all statistical data	analyzed all statistical data	Analyzed the data	Formal analysis	YES
5562723	28861096	XH	PLoS52	conceived the topic|wrote the manuscript	conceived the topic	Conceived and designed the experiments	Conceptualization	YES
5562723	28861096	XH	PLoS52	conceived the topic|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5562723	28861096	YW	PLoS52	conceived the topic	conceived the topic	Conceived and designed the experiments	Conceptualization	YES
4499612	26221588	Shan-Shan Wu	2	contributed equally to this work	contributed equally to this work	-	-	NO
4499612	26221588	Xiao Lin	2	contributed equally to this work	contributed equally to this work	-	-	NO
4406524	25901751	FV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406524	25901751	FV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406524	25901751	FV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406524	25901751	FV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406524	25901751	MR	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406524	25901751	MR	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406524	25901751	SS	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406524	25901751	SS	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6306766	30314305	Both authors	2	were involved in all aspects of manuscript preparation	were involved in all aspects of manuscript preparation	Wrote the paper	Writing - Original Draft	YES
5316152	28212626	HL	PLoS52	conceived and designed experiments|analyzed the data|wrote the manuscript	conceived and designed experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5316152	28212626	HL	PLoS52	conceived and designed experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5316152	28212626	HL	PLoS52	conceived and designed experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5316152	28212626	JZ	PLoS52	conceived and designed experiments|analyzed the data|wrote the manuscript	conceived and designed experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5316152	28212626	JZ	PLoS52	conceived and designed experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5316152	28212626	JZ	PLoS52	conceived and designed experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5316152	28212626	KZ	PLoS52	conceived and designed experiments|performed experiments|analyzed the data|wrote the manuscript	conceived and designed experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5316152	28212626	KZ	PLoS52	conceived and designed experiments|performed experiments|analyzed the data|wrote the manuscript	performed experiments	Performed the experiments	Investigation	YES
5316152	28212626	KZ	PLoS52	conceived and designed experiments|performed experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5316152	28212626	KZ	PLoS52	conceived and designed experiments|performed experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5316152	28212626	QO	PLoS52	conceived and designed experiments|wrote the manuscript	conceived and designed experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5316152	28212626	QO	PLoS52	conceived and designed experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4965597	27469061	AP	PLoS52	conceived and designed the study|wrote the paper|contributed to the interpretation of findings, critical review of manuscript and approval of final manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4965597	27469061	AP	PLoS52	conceived and designed the study|wrote the paper|contributed to the interpretation of findings, critical review of manuscript and approval of final manuscript	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4965597	27469061	AP	PLoS52	conceived and designed the study|wrote the paper|contributed to the interpretation of findings, critical review of manuscript and approval of final manuscript	contributed to the interpretation of findings, critical review of manuscript and approval of final manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4965597	27469061	AS	PLoS52	wrote the paper|were in charge of collection, storage, laboratory testing and analysis of data from the parent study|contributed to the interpretation of findings, critical review of manuscript and approval of final manuscript	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4965597	27469061	AS	PLoS52	wrote the paper|were in charge of collection, storage, laboratory testing and analysis of data from the parent study|contributed to the interpretation of findings, critical review of manuscript and approval of final manuscript	were in charge of collection, storage, laboratory testing and analysis of data from the parent study	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4965597	27469061	AS	PLoS52	wrote the paper|were in charge of collection, storage, laboratory testing and analysis of data from the parent study|contributed to the interpretation of findings, critical review of manuscript and approval of final manuscript	contributed to the interpretation of findings, critical review of manuscript and approval of final manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4965597	27469061	CM	PLoS52	wrote the paper|contributed to the interpretation of findings, critical review of manuscript and approval of final manuscript	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4965597	27469061	CM	PLoS52	wrote the paper|contributed to the interpretation of findings, critical review of manuscript and approval of final manuscript	contributed to the interpretation of findings, critical review of manuscript and approval of final manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4965597	27469061	CW	PLoS52	conceived and designed the study|wrote the paper|contributed to the interpretation of findings, critical review of manuscript and approval of final manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4965597	27469061	CW	PLoS52	conceived and designed the study|wrote the paper|contributed to the interpretation of findings, critical review of manuscript and approval of final manuscript	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4965597	27469061	CW	PLoS52	conceived and designed the study|wrote the paper|contributed to the interpretation of findings, critical review of manuscript and approval of final manuscript	contributed to the interpretation of findings, critical review of manuscript and approval of final manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4965597	27469061	EMP	PLoS52	contributed to the interpretation of findings, critical review of manuscript and approval of final manuscript	contributed to the interpretation of findings, critical review of manuscript and approval of final manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4965597	27469061	EPM	PLoS52	wrote the paper|were in charge of collection, storage, laboratory testing and analysis of data from the parent study	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4965597	27469061	EPM	PLoS52	wrote the paper|were in charge of collection, storage, laboratory testing and analysis of data from the parent study	were in charge of collection, storage, laboratory testing and analysis of data from the parent study	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4965597	27469061	FG	PLoS52	wrote the paper|were in charge of collection, storage, laboratory testing and analysis of data from the parent study|contributed to the interpretation of findings, critical review of manuscript and approval of final manuscript	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4965597	27469061	FG	PLoS52	wrote the paper|were in charge of collection, storage, laboratory testing and analysis of data from the parent study|contributed to the interpretation of findings, critical review of manuscript and approval of final manuscript	were in charge of collection, storage, laboratory testing and analysis of data from the parent study	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4965597	27469061	FG	PLoS52	wrote the paper|were in charge of collection, storage, laboratory testing and analysis of data from the parent study|contributed to the interpretation of findings, critical review of manuscript and approval of final manuscript	contributed to the interpretation of findings, critical review of manuscript and approval of final manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4965597	27469061	JH	PLoS52	wrote the paper|were in charge of collection, storage, laboratory testing and analysis of data from the parent study|contributed to the interpretation of findings, critical review of manuscript and approval of final manuscript	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4965597	27469061	JH	PLoS52	wrote the paper|were in charge of collection, storage, laboratory testing and analysis of data from the parent study|contributed to the interpretation of findings, critical review of manuscript and approval of final manuscript	were in charge of collection, storage, laboratory testing and analysis of data from the parent study	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4965597	27469061	JH	PLoS52	wrote the paper|were in charge of collection, storage, laboratory testing and analysis of data from the parent study|contributed to the interpretation of findings, critical review of manuscript and approval of final manuscript	contributed to the interpretation of findings, critical review of manuscript and approval of final manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4965597	27469061	KK	PLoS52	wrote the paper|contributed to the interpretation of findings, critical review of manuscript and approval of final manuscript	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4965597	27469061	KK	PLoS52	wrote the paper|contributed to the interpretation of findings, critical review of manuscript and approval of final manuscript	contributed to the interpretation of findings, critical review of manuscript and approval of final manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4965597	27469061	LH	PLoS52	conceived and designed the study|wrote the paper|contributed to the interpretation of findings, critical review of manuscript and approval of final manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4965597	27469061	LH	PLoS52	conceived and designed the study|wrote the paper|contributed to the interpretation of findings, critical review of manuscript and approval of final manuscript	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4965597	27469061	LH	PLoS52	conceived and designed the study|wrote the paper|contributed to the interpretation of findings, critical review of manuscript and approval of final manuscript	contributed to the interpretation of findings, critical review of manuscript and approval of final manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4965597	27469061	MR	PLoS52	conceived and designed the study|wrote the paper|contributed to the interpretation of findings, critical review of manuscript and approval of final manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4965597	27469061	MR	PLoS52	conceived and designed the study|wrote the paper|contributed to the interpretation of findings, critical review of manuscript and approval of final manuscript	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4965597	27469061	MR	PLoS52	conceived and designed the study|wrote the paper|contributed to the interpretation of findings, critical review of manuscript and approval of final manuscript	contributed to the interpretation of findings, critical review of manuscript and approval of final manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4965597	27469061	OL	PLoS52	wrote the paper|were in charge of collection, storage, laboratory testing and analysis of data from the parent study|contributed to the interpretation of findings, critical review of manuscript and approval of final manuscript	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4965597	27469061	OL	PLoS52	wrote the paper|were in charge of collection, storage, laboratory testing and analysis of data from the parent study|contributed to the interpretation of findings, critical review of manuscript and approval of final manuscript	were in charge of collection, storage, laboratory testing and analysis of data from the parent study	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4965597	27469061	OL	PLoS52	wrote the paper|were in charge of collection, storage, laboratory testing and analysis of data from the parent study|contributed to the interpretation of findings, critical review of manuscript and approval of final manuscript	contributed to the interpretation of findings, critical review of manuscript and approval of final manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4965597	27469061	RJS	PLoS52	wrote the paper|contributed to the interpretation of findings, critical review of manuscript and approval of final manuscript	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4965597	27469061	RJS	PLoS52	wrote the paper|contributed to the interpretation of findings, critical review of manuscript and approval of final manuscript	contributed to the interpretation of findings, critical review of manuscript and approval of final manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4965597	27469061	SDM	PLoS52	wrote the paper|contributed to the interpretation of findings, critical review of manuscript and approval of final manuscript	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4965597	27469061	SDM	PLoS52	wrote the paper|contributed to the interpretation of findings, critical review of manuscript and approval of final manuscript	contributed to the interpretation of findings, critical review of manuscript and approval of final manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5758835	29326813	Davide Nasi	7	writer and data collection	writer and data collection	Performed the experiments|Wrote the paper	Investigation	YES
5758835	29326813	Fabrizio Mancini	7	data interpretation	data interpretation	Analyzed the data	Formal analysis	YES
5758835	29326813	Massimo Scerrati	7	study concept	study concept	Conceived and designed the experiments	Conceptualization	YES
5758835	29326813	Maurizio Gladi	7	data collection	data collection	Performed the experiments	Investigation	YES
5758835	29326813	Maurizio Iacoangeli	7	clinical case evaluation	clinical case evaluation	-	-	NO
5758835	29326813	Mauro Dobran	7	Corresponding author, writer	Corresponding author, writer	Wrote the paper	-	YES
5758835	29326813	Stefano Sisti	7	histological analysis	histological analysis	Performed the experiments	Investigation	YES
5562724	28861102	AZ	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5562724	28861102	CF	2	provided useful suggestions	provided useful suggestions	-	-	NO
5562724	28861102	HL	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5562724	28861102	JiZ	2	completed the majority of the work for this article, including the experimental design, data analysis, and drafting of the manuscript|carried out bioinformatic analyses	completed the majority of the work for this article, including the experimental design, data analysis, and drafting of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5562724	28861102	JiZ	2	completed the majority of the work for this article, including the experimental design, data analysis, and drafting of the manuscript|carried out bioinformatic analyses	carried out bioinformatic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5562724	28861102	JuZ	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5562724	28861102	LC	2	provided useful suggestions	provided useful suggestions	-	-	NO
5562724	28861102	LW	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5562724	28861102	PL	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5562724	28861102	QD	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5562724	28861102	SL	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5562724	28861102	SW	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5562724	28861102	YC	2	carried out bioinformatic analyses	carried out bioinformatic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5562724	28861102	YL	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
6306767	30545072	A.C.	CRediT	Methodology|Validation|Writing--Review and editing	Methodology	Performed the experiments	Methodology	YES
6306767	30545072	A.C.	CRediT	Methodology|Validation|Writing--Review and editing	Validation	Performed the experiments	Validation	YES
6306767	30545072	A.C.	CRediT	Methodology|Validation|Writing--Review and editing	Writing--Review and editing	Wrote the paper	Writing - Review & Editing	YES
6306767	30545072	J.W.	CRediT	Methodology|Validation|Writing--Review and editing|Supervision	Methodology	Performed the experiments	Methodology	YES
6306767	30545072	J.W.	CRediT	Methodology|Validation|Writing--Review and editing|Supervision	Validation	Performed the experiments	Validation	YES
6306767	30545072	J.W.	CRediT	Methodology|Validation|Writing--Review and editing|Supervision	Writing--Review and editing	Wrote the paper	Writing - Review & Editing	YES
6306767	30545072	J.W.	CRediT	Methodology|Validation|Writing--Review and editing|Supervision	Supervision	-	Supervision	YES
6306767	30545072	K.K.	CRediT	Validation|Writing--Review and editing	Validation	Performed the experiments	Validation	YES
6306767	30545072	K.K.	CRediT	Validation|Writing--Review and editing	Writing--Review and editing	Wrote the paper	Writing - Review & Editing	YES
6306767	30545072	N.C.	CRediT	Methodology	Methodology	Performed the experiments	Methodology	YES
6306767	30545072	N.G.	CRediT	Investigation|Data curation|Writing--Review and editing	Investigation	Performed the experiments	Investigation	YES
6306767	30545072	N.G.	CRediT	Investigation|Data curation|Writing--Review and editing	Data curation	Analyzed the data	Data curation	YES
6306767	30545072	N.G.	CRediT	Investigation|Data curation|Writing--Review and editing	Writing--Review and editing	Wrote the paper	Writing - Review & Editing	YES
6306767	30545072	N.V.	CRediT	Methodology|Validation|Formal analysis|Investigation|Data curation	Methodology	Performed the experiments	Methodology	YES
6306767	30545072	N.V.	CRediT	Methodology|Validation|Formal analysis|Investigation|Data curation	Validation	Performed the experiments	Validation	YES
6306767	30545072	N.V.	CRediT	Methodology|Validation|Formal analysis|Investigation|Data curation	Formal analysis	Analyzed the data	Formal analysis	YES
6306767	30545072	N.V.	CRediT	Methodology|Validation|Formal analysis|Investigation|Data curation	Investigation	Performed the experiments	Investigation	YES
6306767	30545072	N.V.	CRediT	Methodology|Validation|Formal analysis|Investigation|Data curation	Data curation	Analyzed the data	Data curation	YES
6306767	30545072	Z.J.	CRediT	Methodology|Formal analysis|Investigation|Resources|Writing--Original draft preparation|Supervision|Project administration	Methodology	Performed the experiments	Methodology	YES
6306767	30545072	Z.J.	CRediT	Methodology|Formal analysis|Investigation|Resources|Writing--Original draft preparation|Supervision|Project administration	Formal analysis	Analyzed the data	Formal analysis	YES
6306767	30545072	Z.J.	CRediT	Methodology|Formal analysis|Investigation|Resources|Writing--Original draft preparation|Supervision|Project administration	Investigation	Performed the experiments	Investigation	YES
6306767	30545072	Z.J.	CRediT	Methodology|Formal analysis|Investigation|Resources|Writing--Original draft preparation|Supervision|Project administration	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6306767	30545072	Z.J.	CRediT	Methodology|Formal analysis|Investigation|Resources|Writing--Original draft preparation|Supervision|Project administration	Writing--Original draft preparation	Wrote the paper	Writing - Original Draft	YES
6306767	30545072	Z.J.	CRediT	Methodology|Formal analysis|Investigation|Resources|Writing--Original draft preparation|Supervision|Project administration	Supervision	-	Supervision	YES
6306767	30545072	Z.J.	CRediT	Methodology|Formal analysis|Investigation|Resources|Writing--Original draft preparation|Supervision|Project administration	Project administration	-	Project administration	YES
4406530	25901368	AA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406530	25901368	AA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406530	25901368	AA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406530	25901368	AA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406530	25901368	AM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406530	25901368	C. Thomson	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4406530	25901368	C. Thrasivoulou	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Helped in the design of some experiments	Performed the experiments	Performed the experiments	Investigation	YES
4406530	25901368	C. Thrasivoulou	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Helped in the design of some experiments	Analyzed the data	Analyzed the data	Formal analysis	YES
4406530	25901368	C. Thrasivoulou	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Helped in the design of some experiments	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406530	25901368	C. Thrasivoulou	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Helped in the design of some experiments	Helped in the design of some experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4406530	25901368	HRHP	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406530	25901368	JRM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406530	25901368	KA	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4406530	25901368	KA	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4406530	25901368	MA	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Helped in the design of some experiments	Performed the experiments	Performed the experiments	Investigation	YES
4406530	25901368	MA	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Helped in the design of some experiments	Analyzed the data	Analyzed the data	Formal analysis	YES
4406530	25901368	MA	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Helped in the design of some experiments	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406530	25901368	MA	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Helped in the design of some experiments	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406530	25901368	MA	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Helped in the design of some experiments	Helped in the design of some experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4406530	25901368	MM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4406530	25901368	R. Hamblin	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4406530	25901368	R. Henrique	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4406530	25901368	R. Henrique	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406530	25901368	RD	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
3654283	23710137	Bin He	2	helped to revise the paper	helped to revise the paper	Wrote the paper	Writing - Review & Editing	YES
3654283	23710137	Each author	2	has made an important scientific contribution to the study and is thoroughly familiar with the primary data	has made an important scientific contribution to the study and is thoroughly familiar with the primary data	Contributed reagents/materials/analysis tools	Resources	YES
3654283	23710137	Jing Liu	2	participated in the design of the study	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
4976295	27499064	DM	2	critically revised the manuscript for important intellectual content and for final approval	critically revised the manuscript for important intellectual content and for final approval	Wrote the paper	Writing - Review & Editing	YES
4976295	27499064	JSGM	2	acquired the data|critically revised the manuscript for important intellectual content and for final approval|obtained funding	acquired the data	Performed the experiments	Investigation	YES
4976295	27499064	JSGM	2	acquired the data|critically revised the manuscript for important intellectual content and for final approval|obtained funding	critically revised the manuscript for important intellectual content and for final approval	Wrote the paper	Writing - Review & Editing	YES
4976295	27499064	JSGM	2	acquired the data|critically revised the manuscript for important intellectual content and for final approval|obtained funding	obtained funding	-	Funding acquisition	YES
4976295	27499064	MH	2	critically revised the manuscript for important intellectual content and for final approval	critically revised the manuscript for important intellectual content and for final approval	Wrote the paper	Writing - Review & Editing	YES
4976295	27499064	PRH	2	acquired the data|critically revised the manuscript for important intellectual content and for final approval	acquired the data	Performed the experiments	Investigation	YES
4976295	27499064	PRH	2	acquired the data|critically revised the manuscript for important intellectual content and for final approval	critically revised the manuscript for important intellectual content and for final approval	Wrote the paper	Writing - Review & Editing	YES
4976295	27499064	VDL	2	conceptualized and designed the study, performed the analysis and interpretation of the data, performed statistical analysis, and drafted the manuscript|acquired the data|critically revised the manuscript for important intellectual content and for final approval|obtained funding|provided administrative, technical and material support	conceptualized and designed the study, performed the analysis and interpretation of the data, performed statistical analysis, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4976295	27499064	VDL	2	conceptualized and designed the study, performed the analysis and interpretation of the data, performed statistical analysis, and drafted the manuscript|acquired the data|critically revised the manuscript for important intellectual content and for final approval|obtained funding|provided administrative, technical and material support	acquired the data	Performed the experiments	Investigation	YES
4976295	27499064	VDL	2	conceptualized and designed the study, performed the analysis and interpretation of the data, performed statistical analysis, and drafted the manuscript|acquired the data|critically revised the manuscript for important intellectual content and for final approval|obtained funding|provided administrative, technical and material support	critically revised the manuscript for important intellectual content and for final approval	Wrote the paper	Writing - Review & Editing	YES
4976295	27499064	VDL	2	conceptualized and designed the study, performed the analysis and interpretation of the data, performed statistical analysis, and drafted the manuscript|acquired the data|critically revised the manuscript for important intellectual content and for final approval|obtained funding|provided administrative, technical and material support	obtained funding	-	Funding acquisition	YES
4976295	27499064	VDL	2	conceptualized and designed the study, performed the analysis and interpretation of the data, performed statistical analysis, and drafted the manuscript|acquired the data|critically revised the manuscript for important intellectual content and for final approval|obtained funding|provided administrative, technical and material support	provided administrative, technical and material support	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Project administration|Resources	YES
4976295	27499064	WC	2	acquired the data|critically revised the manuscript for important intellectual content and for final approval	acquired the data	Performed the experiments	Investigation	YES
4976295	27499064	WC	2	acquired the data|critically revised the manuscript for important intellectual content and for final approval	critically revised the manuscript for important intellectual content and for final approval	Wrote the paper	Writing - Review & Editing	YES
5911168	29736100	J.S.	2	made substantial contribution to conception and design, acquisition of data, analysis and interpretation of data, drafted the article, critically revised the article for important intellectual content and approved final version to be published	made substantial contribution to conception and design, acquisition of data, analysis and interpretation of data, drafted the article, critically revised the article for important intellectual content and approved final version to be published	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5911168	29736100	L.R.T.	2	made substantial contribution to analysis and interpretation of data	made substantial contribution to analysis and interpretation of data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5911168	29736100	S.H.	2	drafted the article|made substantial contribution to acquisition of data	drafted the article	Wrote the paper	Writing - Original Draft	YES
5911168	29736100	S.H.	2	drafted the article|made substantial contribution to acquisition of data	made substantial contribution to acquisition of data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5911168	29736100	S.S.A.	2	made substantial contribution to acquisition of data	made substantial contribution to acquisition of data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5316172	28212609	CCK	PLoS52	conceived and designed the experiments|conducted the experiments and analyzed the data	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5316172	28212609	CCK	PLoS52	conceived and designed the experiments|conducted the experiments and analyzed the data	conducted the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5316172	28212609	HYW	PLoS52	conducted the experiments and analyzed the data	conducted the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5316172	28212609	MHH	PLoS52	conceived and designed the experiments|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5316172	28212609	MHH	PLoS52	conceived and designed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5316172	28212609	TYC	PLoS52	conceived and designed the experiments|conducted the experiments and analyzed the data	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5316172	28212609	TYC	PLoS52	conceived and designed the experiments|conducted the experiments and analyzed the data	conducted the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5316172	28212609	YAJ	PLoS52	conducted the experiments and analyzed the data	conducted the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5911169	29736108	Bostanitis Ioannis	7	Intervention, critical revision of the article, approval of the article	Intervention, critical revision of the article, approval of the article	Wrote the paper	Writing - Review & Editing	YES
5911169	29736108	Koutsambasopoulos Konstantinos	7	Concept, data analysis, interpretation, critical revision of the article, approval of the article	Concept, data analysis, interpretation, critical revision of the article, approval of the article	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Review & Editing	YES
5911169	29736108	Samaras Antonios	7	Intervention, critical revision of the article, approval of the article	Intervention, critical revision of the article, approval of the article	Wrote the paper	Writing - Review & Editing	YES
5911169	29736108	Vogiatzis Ioannis	7	Design, drafting article, critical revision of the article, approval of the article	Design, drafting article, critical revision of the article, approval of the article	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4406531	25902309	EN	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406531	25902309	EN	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406531	25902309	EN	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406531	25902309	HK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406531	25902309	HK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406531	25902309	HK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406531	25902309	HK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406531	25902309	VSP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406531	25902309	VSP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4406531	25902309	VSP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4406531	25902309	VSP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
3368312	22690332	A. J. Bell	2	assisted with study design, analysis, and interpretation, wrote drafts, and made revisions of article and final approval for submission	assisted with study design, analysis, and interpretation, wrote drafts, and made revisions of article and final approval for submission	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
3368312	22690332	A. Katschke	2	assisted with study design, analysis and interpretation, drafts and revision of article, and final approval for submission	assisted with study design, analysis and interpretation, drafts and revision of article, and final approval for submission	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
3368312	22690332	B. S. Musick	2	prepared data for analysis, assisted with study design and analysis, reviewed drafts, and approved final draft for submission	prepared data for analysis, assisted with study design and analysis, reviewed drafts, and approved final draft for submission	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3368312	22690332	C. Shen	2	assisted with study design, analysis and interpretation, drafts and revision of article, and final approval for submission	assisted with study design, analysis and interpretation, drafts and revision of article, and final approval for submission	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
3368312	22690332	G. Simiyu	2	assisted with acquisition of data, reviewed drafts, and final approval for submission	assisted with acquisition of data, reviewed drafts, and final approval for submission	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3368312	22690332	H. Liu	2	assisted with study design and co-led the final analysis, revision of article, and final approval for submission	assisted with study design and co-led the final analysis, revision of article, and final approval for submission	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
3368312	22690332	J. E. Sidle	2	assisted with study design, acquisition of data, revision of article, and final approval for submission	assisted with study design, acquisition of data, revision of article, and final approval for submission	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
3368312	22690332	K. Wools-Kaloustian	2	assisted with study design, acquisition of data, revision of article, and final approval for submission	assisted with study design, acquisition of data, revision of article, and final approval for submission	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
3368312	22690332	M.D.	2	assisted with study design, acquisition of data, revision of article, and final approval for submission|assisted with study design, acquisition of data, revision of article, and final approval for submission	assisted with study design, acquisition of data, revision of article, and final approval for submission	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
3368312	22690332	M.D.	2	assisted with study design, acquisition of data, revision of article, and final approval for submission|assisted with study design, acquisition of data, revision of article, and final approval for submission	assisted with study design, acquisition of data, revision of article, and final approval for submission	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
3368312	22690332	M.P.H.	2	assisted with study design, analysis, and interpretation, wrote drafts, and made revisions of article and final approval for submission	assisted with study design, analysis, and interpretation, wrote drafts, and made revisions of article and final approval for submission	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
3368312	22690332	M.S.	2	assisted with study design, acquisition of data, revision of article, and final approval for submission|assisted with study design, analysis and interpretation, drafts and revision of article, and final approval for submission|prepared data for analysis, assisted with study design and analysis, reviewed drafts, and approved final draft for submission	assisted with study design, acquisition of data, revision of article, and final approval for submission	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
3368312	22690332	M.S.	2	assisted with study design, acquisition of data, revision of article, and final approval for submission|assisted with study design, analysis and interpretation, drafts and revision of article, and final approval for submission|prepared data for analysis, assisted with study design and analysis, reviewed drafts, and approved final draft for submission	assisted with study design, analysis and interpretation, drafts and revision of article, and final approval for submission	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
3368312	22690332	M.S.	2	assisted with study design, acquisition of data, revision of article, and final approval for submission|assisted with study design, analysis and interpretation, drafts and revision of article, and final approval for submission|prepared data for analysis, assisted with study design and analysis, reviewed drafts, and approved final draft for submission	prepared data for analysis, assisted with study design and analysis, reviewed drafts, and approved final draft for submission	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3368312	22690332	P. Braitstein	2	conceived the idea, led the study design, analysis, and interpretation, reviewed drafts and is responsible for final submission	conceived the idea, led the study design, analysis, and interpretation, reviewed drafts and is responsible for final submission	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
3368312	22690332	Ph.D.	2	assisted with study design and co-led the final analysis, revision of article, and final approval for submission|assisted with study design, analysis and interpretation, drafts and revision of article, and final approval for submission|conceived the idea, led the study design, analysis, and interpretation, reviewed drafts and is responsible for final submission	assisted with study design and co-led the final analysis, revision of article, and final approval for submission	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
3368312	22690332	Ph.D.	2	assisted with study design and co-led the final analysis, revision of article, and final approval for submission|assisted with study design, analysis and interpretation, drafts and revision of article, and final approval for submission|conceived the idea, led the study design, analysis, and interpretation, reviewed drafts and is responsible for final submission	assisted with study design, analysis and interpretation, drafts and revision of article, and final approval for submission	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
3368312	22690332	Ph.D.	2	assisted with study design and co-led the final analysis, revision of article, and final approval for submission|assisted with study design, analysis and interpretation, drafts and revision of article, and final approval for submission|conceived the idea, led the study design, analysis, and interpretation, reviewed drafts and is responsible for final submission	conceived the idea, led the study design, analysis, and interpretation, reviewed drafts and is responsible for final submission	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
4978859	27507249	EN	2	provided input to the design and analysis and edited the manuscript	provided input to the design and analysis and edited the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Review & Editing	YES
4978859	27507249	MPF	2	designed the study, conducted the literature searches, analyzed the data and drafted the manuscript	designed the study, conducted the literature searches, analyzed the data and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4978859	27507249	PG	2	provided input to the design and analysis and edited the manuscript	provided input to the design and analysis and edited the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Review & Editing	YES
4978859	27507249	RB	2	provided input to the design and analysis and edited the manuscript	provided input to the design and analysis and edited the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Review & Editing	YES
4978859	27507249	SR	2	designed the study, conducted the literature searches, analyzed the data and drafted the manuscript	designed the study, conducted the literature searches, analyzed the data and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4978859	27507249	TB	2	provided input to the design and analysis and edited the manuscript	provided input to the design and analysis and edited the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Review & Editing	YES
6306770	30360487	A.F.	CRediT	Conceptualization|Methodology|Formal analysis|Writing-original draft preparation|Writing-review & editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6306770	30360487	A.F.	CRediT	Conceptualization|Methodology|Formal analysis|Writing-original draft preparation|Writing-review & editing	Methodology	Performed the experiments	Methodology	YES
6306770	30360487	A.F.	CRediT	Conceptualization|Methodology|Formal analysis|Writing-original draft preparation|Writing-review & editing	Formal analysis	Analyzed the data	Formal analysis	YES
6306770	30360487	A.F.	CRediT	Conceptualization|Methodology|Formal analysis|Writing-original draft preparation|Writing-review & editing	Writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
6306770	30360487	A.F.	CRediT	Conceptualization|Methodology|Formal analysis|Writing-original draft preparation|Writing-review & editing	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6306770	30360487	C.B.	CRediT	Conceptualization|Methodology|Formal analysis|Writing-review & editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6306770	30360487	C.B.	CRediT	Conceptualization|Methodology|Formal analysis|Writing-review & editing	Methodology	Performed the experiments	Methodology	YES
6306770	30360487	C.B.	CRediT	Conceptualization|Methodology|Formal analysis|Writing-review & editing	Formal analysis	Analyzed the data	Formal analysis	YES
6306770	30360487	C.B.	CRediT	Conceptualization|Methodology|Formal analysis|Writing-review & editing	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6306770	30360487	H.E.-S.	CRediT	Formal analysis|Writing-original draft preparation|Writing-review & editing	Formal analysis	Analyzed the data	Formal analysis	YES
6306770	30360487	H.E.-S.	CRediT	Formal analysis|Writing-original draft preparation|Writing-review & editing	Writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
6306770	30360487	H.E.-S.	CRediT	Formal analysis|Writing-original draft preparation|Writing-review & editing	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6306770	30360487	O.D.	CRediT	Methodology|Formal analysis|Writing-review & editing	Methodology	Performed the experiments	Methodology	YES
6306770	30360487	O.D.	CRediT	Methodology|Formal analysis|Writing-review & editing	Formal analysis	Analyzed the data	Formal analysis	YES
6306770	30360487	O.D.	CRediT	Methodology|Formal analysis|Writing-review & editing	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6306770	30360487	O.S.	CRediT	Methodology|Formal analysis|Writing-review & editing	Methodology	Performed the experiments	Methodology	YES
6306770	30360487	O.S.	CRediT	Methodology|Formal analysis|Writing-review & editing	Formal analysis	Analyzed the data	Formal analysis	YES
6306770	30360487	O.S.	CRediT	Methodology|Formal analysis|Writing-review & editing	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6306770	30360487	R.H.	CRediT	Formal analysis|Writing-review & editing	Formal analysis	Analyzed the data	Formal analysis	YES
6306770	30360487	R.H.	CRediT	Formal analysis|Writing-review & editing	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6306770	30360487	T.W.	CRediT	Conceptualization|Methodology|Writing-review & editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6306770	30360487	T.W.	CRediT	Conceptualization|Methodology|Writing-review & editing	Methodology	Performed the experiments	Methodology	YES
6306770	30360487	T.W.	CRediT	Conceptualization|Methodology|Writing-review & editing	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
5563355	28868058	FB	PLoS52	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5563355	28868058	HS	PLoS52	performed data analysis	performed data analysis	Analyzed the data	Formal analysis	YES
5563355	28868058	HZ	PLoS52	conceived and designed the experiments|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5563355	28868058	HZ	PLoS52	conceived and designed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5563355	28868058	LX	PLoS52	carried out the experiments|performed data analysis	carried out the experiments	Performed the experiments	Investigation	YES
5563355	28868058	LX	PLoS52	carried out the experiments|performed data analysis	performed data analysis	Analyzed the data	Formal analysis	YES
5563355	28868058	QY	PLoS52	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5563355	28868058	YY	PLoS52	conceived and designed the experiments|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5563355	28868058	YY	PLoS52	conceived and designed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3654284	23710153	Huimei Wang	2	contributed to data analysis, laboratory assay, and paper preparation	contributed to data analysis, laboratory assay, and paper preparation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3654284	23710153	Wei Liu	2	contributed to field data measurement	contributed to field data measurement	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
3654284	23710153	Wenjie Wang	2	contributed to experiment design and paper preparation and revision	contributed to experiment design and paper preparation and revision	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
3654284	23710153	Yuangang Zu	2	provided long-term data for thinning history and experiment design	provided long-term data for thinning history and experiment design	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Methodology|Resources	YES
5316186	28212608	CM	2	provided useful input for the analyses and helped edit the manuscript	provided useful input for the analyses and helped edit the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5316186	28212608	JRL	2	provided useful input for the analyses and helped edit the manuscript	provided useful input for the analyses and helped edit the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5316186	28212608	KB	2	performed animal experiments and sample preparation	performed animal experiments and sample preparation	Performed the experiments	Investigation	YES
5316186	28212608	QZ	2	provided useful input for the analyses and helped edit the manuscript	provided useful input for the analyses and helped edit the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5316186	28212608	RNC	2	provided useful input for the analyses and helped edit the manuscript	provided useful input for the analyses and helped edit the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5316186	28212608	WZ	2	provided useful input for the analyses and helped edit the manuscript	provided useful input for the analyses and helped edit the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5316186	28212608	YC	2	carried out the analyses and also participated in the study design|wrote the manuscript	carried out the analyses and also participated in the study design	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5316186	28212608	YC	2	carried out the analyses and also participated in the study design|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5316186	28212608	ZDZ	2	conceived and designed this study|wrote the manuscript	conceived and designed this study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5316186	28212608	ZDZ	2	conceived and designed this study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4406532	25902153	DOW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Conceived the idea and wrote the protocol|Wrote the first draft and all authors made edits and contributed significantly to the final version of the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406532	25902153	DOW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Conceived the idea and wrote the protocol|Wrote the first draft and all authors made edits and contributed significantly to the final version of the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4406532	25902153	DOW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Conceived the idea and wrote the protocol|Wrote the first draft and all authors made edits and contributed significantly to the final version of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4406532	25902153	DOW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Conceived the idea and wrote the protocol|Wrote the first draft and all authors made edits and contributed significantly to the final version of the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406532	25902153	DOW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Conceived the idea and wrote the protocol|Wrote the first draft and all authors made edits and contributed significantly to the final version of the manuscript	Conceived the idea and wrote the protocol	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
4406532	25902153	DOW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Conceived the idea and wrote the protocol|Wrote the first draft and all authors made edits and contributed significantly to the final version of the manuscript	Wrote the first draft and all authors made edits and contributed significantly to the final version of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4406532	25902153	ELZ	PLoS5	Analyzed the data|Wrote the paper|Wrote the first draft and all authors made edits and contributed significantly to the final version of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4406532	25902153	ELZ	PLoS5	Analyzed the data|Wrote the paper|Wrote the first draft and all authors made edits and contributed significantly to the final version of the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406532	25902153	ELZ	PLoS5	Analyzed the data|Wrote the paper|Wrote the first draft and all authors made edits and contributed significantly to the final version of the manuscript	Wrote the first draft and all authors made edits and contributed significantly to the final version of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4406532	25902153	JWD	PLoS5	Analyzed the data|Wrote the paper|Wrote the first draft and all authors made edits and contributed significantly to the final version of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4406532	25902153	JWD	PLoS5	Analyzed the data|Wrote the paper|Wrote the first draft and all authors made edits and contributed significantly to the final version of the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406532	25902153	JWD	PLoS5	Analyzed the data|Wrote the paper|Wrote the first draft and all authors made edits and contributed significantly to the final version of the manuscript	Wrote the first draft and all authors made edits and contributed significantly to the final version of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4406532	25902153	MWH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Conceived the idea and wrote the protocol|Screened the study subjects and collected the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406532	25902153	MWH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Conceived the idea and wrote the protocol|Screened the study subjects and collected the data	Performed the experiments	Performed the experiments	Investigation	YES
4406532	25902153	MWH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Conceived the idea and wrote the protocol|Screened the study subjects and collected the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4406532	25902153	MWH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Conceived the idea and wrote the protocol|Screened the study subjects and collected the data	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406532	25902153	MWH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Conceived the idea and wrote the protocol|Screened the study subjects and collected the data	Conceived the idea and wrote the protocol	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
4406532	25902153	MWH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Conceived the idea and wrote the protocol|Screened the study subjects and collected the data	Screened the study subjects and collected the data	Performed the experiments	Investigation	YES
4406532	25902153	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Conceived the idea and wrote the protocol|Wrote the first draft and all authors made edits and contributed significantly to the final version of the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406532	25902153	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Conceived the idea and wrote the protocol|Wrote the first draft and all authors made edits and contributed significantly to the final version of the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4406532	25902153	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Conceived the idea and wrote the protocol|Wrote the first draft and all authors made edits and contributed significantly to the final version of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4406532	25902153	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Conceived the idea and wrote the protocol|Wrote the first draft and all authors made edits and contributed significantly to the final version of the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406532	25902153	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Conceived the idea and wrote the protocol|Wrote the first draft and all authors made edits and contributed significantly to the final version of the manuscript	Conceived the idea and wrote the protocol	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
4406532	25902153	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Conceived the idea and wrote the protocol|Wrote the first draft and all authors made edits and contributed significantly to the final version of the manuscript	Wrote the first draft and all authors made edits and contributed significantly to the final version of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5911170	29736102	Adela Sabic	2	substantial contribution to conception and design, substantial contribution to acquisition of data, substantial contribution to analysis and interpretation of data, critically revising the article for important intellectual content	substantial contribution to conception and design, substantial contribution to acquisition of data, substantial contribution to analysis and interpretation of data, critically revising the article for important intellectual content	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Resources|Writing - Review & Editing	YES
5911170	29736102	Dzevad Sabic	2	substantial contribution to conception and design, substantial contribution to acquisition of data, substantial contribution to analysis and interpretation of data, drafting the article, final approval of the version to be published	substantial contribution to conception and design, substantial contribution to acquisition of data, substantial contribution to analysis and interpretation of data, drafting the article, final approval of the version to be published	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Resources|Writing - Original Draft	YES
5911170	29736102	Olivera Batic-Mujanovic	2	critically revising the article for important intellectual content, final approval of the version to be published	critically revising the article for important intellectual content, final approval of the version to be published	Wrote the paper	Writing - Review & Editing	YES
5563357	28868062	BJ	PLoS52	contributed to sample preparation, experimental execution and data analysis|performed the bioinformatics analysis	contributed to sample preparation, experimental execution and data analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5563357	28868062	BJ	PLoS52	contributed to sample preparation, experimental execution and data analysis|performed the bioinformatics analysis	performed the bioinformatics analysis	Performed the experiments	Formal analysis|Investigation	YES
5563357	28868062	DD	PLoS52	contributed to the study design	contributed to the study design	Conceived and designed the experiments	Methodology	YES
5563357	28868062	HL	PLoS52	contributed to sample preparation, experimental execution and data analysis	contributed to sample preparation, experimental execution and data analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5563357	28868062	LY	PLoS52	contributed to sample preparation, experimental execution and data analysis	contributed to sample preparation, experimental execution and data analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5563357	28868062	MC	PLoS52	contributed to the study design|contributed to sample preparation, experimental execution and data analysis|wrote the paper	contributed to the study design	Conceived and designed the experiments	Methodology	YES
5563357	28868062	MC	PLoS52	contributed to the study design|contributed to sample preparation, experimental execution and data analysis|wrote the paper	contributed to sample preparation, experimental execution and data analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5563357	28868062	MC	PLoS52	contributed to the study design|contributed to sample preparation, experimental execution and data analysis|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5563357	28868062	RZ	PLoS52	contributed to sample preparation, experimental execution and data analysis	contributed to sample preparation, experimental execution and data analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5563357	28868062	XK	PLoS52	contributed to sample preparation, experimental execution and data analysis	contributed to sample preparation, experimental execution and data analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5563357	28868062	YZ	PLoS52	contributed to sample preparation, experimental execution and data analysis	contributed to sample preparation, experimental execution and data analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5563357	28868062	ZL	PLoS52	contributed to sample preparation, experimental execution and data analysis	contributed to sample preparation, experimental execution and data analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5563357	28868062	ZY	PLoS52	contributed to the study design|wrote the paper	contributed to the study design	Conceived and designed the experiments	Methodology	YES
5563357	28868062	ZY	PLoS52	contributed to the study design|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5316204	28212627	AT	2	conceived and designed the project|contributed to data interpretation and presentation	conceived and designed the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5316204	28212627	AT	2	conceived and designed the project|contributed to data interpretation and presentation	contributed to data interpretation and presentation	Analyzed the data	Formal analysis	YES
5316204	28212627	DD	2	performed bioinformatics analysis	performed bioinformatics analysis	Performed the experiments	Formal analysis|Investigation	YES
5316204	28212627	FG	2	conceived and designed the project|wrote the manuscript	conceived and designed the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5316204	28212627	FG	2	conceived and designed the project|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5316204	28212627	FZ	2	contributed to data interpretation and presentation	contributed to data interpretation and presentation	Analyzed the data	Formal analysis	YES
5316204	28212627	LL	2	performed bioinformatics analysis	performed bioinformatics analysis	Performed the experiments	Formal analysis|Investigation	YES
5316204	28212627	ML	2	conceived and designed the project|wrote the manuscript	conceived and designed the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5316204	28212627	ML	2	conceived and designed the project|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5760313	29326815	Medical Students	7	Sean Christensen, Riley Stroman, and Tyler Hammett, USC Medical School, Columbia, SC	Sean Christensen, Riley Stroman, and Tyler Hammett, USC Medical School, Columbia, SC	-	-	NO
5760313	29326815	Principal Authors Office	7	251 Cox Street, CWEB Rm 1163, Mobile, AL 36604-3301. Email address: jglasser@health.southalabama.edu	251 Cox Street, CWEB Rm 1163, Mobile, AL 36604-3301. Email address: jglasser@health.southalabama.edu	-	-	NO
5760313	29326815	Research Assistants	7	Martin Durkin, MD and Ret Haney, ME, Palmetto Health, Columbia, SC	Martin Durkin, MD and Ret Haney, ME, Palmetto Health, Columbia, SC	-	-	NO
5760313	29326815	Sponsoring Author	7	James M. Nottingham, MD, FACS, Professor of Surgery, university of south carolina school of medicine, 2 Richland Medical Park, Suite 300, Columbia, South Carolina 29203	James M. Nottingham, MD, FACS, Professor of Surgery, university of south carolina school of medicine, 2 Richland Medical Park, Suite 300, Columbia, South Carolina 29203	Performed the experiments	Investigation	YES
6306773	30274303	A.M.J.	2	designed the study together|were involved in parts of the data analysis|revised as well as approved the submitted version of the manuscript|revised as well as approved the submitted version of the manuscript	designed the study together	Conceived and designed the experiments	Methodology	YES
6306773	30274303	A.M.J.	2	designed the study together|were involved in parts of the data analysis|revised as well as approved the submitted version of the manuscript|revised as well as approved the submitted version of the manuscript	were involved in parts of the data analysis	Analyzed the data	Formal analysis	YES
6306773	30274303	A.M.J.	2	designed the study together|were involved in parts of the data analysis|revised as well as approved the submitted version of the manuscript|revised as well as approved the submitted version of the manuscript	revised as well as approved the submitted version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
6306773	30274303	A.M.J.	2	designed the study together|were involved in parts of the data analysis|revised as well as approved the submitted version of the manuscript|revised as well as approved the submitted version of the manuscript	revised as well as approved the submitted version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
6306773	30274303	N.K.	2	designed the study together|were involved in parts of the data analysis|revised as well as approved the submitted version of the manuscript|revised as well as approved the submitted version of the manuscript	designed the study together	Conceived and designed the experiments	Methodology	YES
6306773	30274303	N.K.	2	designed the study together|were involved in parts of the data analysis|revised as well as approved the submitted version of the manuscript|revised as well as approved the submitted version of the manuscript	were involved in parts of the data analysis	Analyzed the data	Formal analysis	YES
6306773	30274303	N.K.	2	designed the study together|were involved in parts of the data analysis|revised as well as approved the submitted version of the manuscript|revised as well as approved the submitted version of the manuscript	revised as well as approved the submitted version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
6306773	30274303	N.K.	2	designed the study together|were involved in parts of the data analysis|revised as well as approved the submitted version of the manuscript|revised as well as approved the submitted version of the manuscript	revised as well as approved the submitted version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
6306773	30274303	S.v.S.	2	designed the study together|gathered and analyzed the data|revised as well as approved the submitted version of the manuscript	designed the study together	Conceived and designed the experiments	Methodology	YES
6306773	30274303	S.v.S.	2	designed the study together|gathered and analyzed the data|revised as well as approved the submitted version of the manuscript	gathered and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6306773	30274303	S.v.S.	2	designed the study together|gathered and analyzed the data|revised as well as approved the submitted version of the manuscript	revised as well as approved the submitted version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4981647	27515018	GF	PLoS52	performed the study and experiments	performed the study and experiments	Performed the experiments	Investigation	YES
4981647	27515018	HS	PLoS52	conceived and designed the experiments|wrote and revised the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4981647	27515018	HS	PLoS52	conceived and designed the experiments|wrote and revised the manuscript	wrote and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4981647	27515018	HZ	PLoS52	conceived and designed the experiments|performed the study and experiments|analyzed the data|wrote and revised the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4981647	27515018	HZ	PLoS52	conceived and designed the experiments|performed the study and experiments|analyzed the data|wrote and revised the manuscript	performed the study and experiments	Performed the experiments	Investigation	YES
4981647	27515018	HZ	PLoS52	conceived and designed the experiments|performed the study and experiments|analyzed the data|wrote and revised the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
4981647	27515018	HZ	PLoS52	conceived and designed the experiments|performed the study and experiments|analyzed the data|wrote and revised the manuscript	wrote and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4981647	27515018	JH	PLoS52	performed the study and experiments	performed the study and experiments	Performed the experiments	Investigation	YES
4981647	27515018	JX	PLoS52	conceived and designed the experiments|performed the study and experiments|analyzed the data|wrote and revised the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4981647	27515018	JX	PLoS52	conceived and designed the experiments|performed the study and experiments|analyzed the data|wrote and revised the manuscript	performed the study and experiments	Performed the experiments	Investigation	YES
4981647	27515018	JX	PLoS52	conceived and designed the experiments|performed the study and experiments|analyzed the data|wrote and revised the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
4981647	27515018	JX	PLoS52	conceived and designed the experiments|performed the study and experiments|analyzed the data|wrote and revised the manuscript	wrote and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4981647	27515018	LL	PLoS52	performed the study and experiments	performed the study and experiments	Performed the experiments	Investigation	YES
4981647	27515018	MZ	PLoS52	performed the study and experiments	performed the study and experiments	Performed the experiments	Investigation	YES
4981647	27515018	QH	PLoS52	performed the study and experiments	performed the study and experiments	Performed the experiments	Investigation	YES
4981647	27515018	WG	PLoS52	contributed reagents/materials/analysis tools	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4981647	27515018	XC	PLoS52	performed the study and experiments	performed the study and experiments	Performed the experiments	Investigation	YES
4981647	27515018	YJ	PLoS52	contributed reagents/materials/analysis tools	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4981647	27515018	YY	PLoS52	performed the study and experiments|wrote and revised the manuscript	performed the study and experiments	Performed the experiments	Investigation	YES
4981647	27515018	YY	PLoS52	performed the study and experiments|wrote and revised the manuscript	wrote and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4981647	27515018	ZW	PLoS52	performed the study and experiments	performed the study and experiments	Performed the experiments	Investigation	YES
4981647	27515018	ZZ	PLoS52	analyzed the data|contributed reagents/materials/analysis tools	analyzed the data	Analyzed the data	Formal analysis	YES
4981647	27515018	ZZ	PLoS52	analyzed the data|contributed reagents/materials/analysis tools	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406536	25902264	GQZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Revised the manuscript draft	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406536	25902264	GQZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Revised the manuscript draft	Performed the experiments	Performed the experiments	Investigation	YES
4406536	25902264	GQZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Revised the manuscript draft	Analyzed the data	Analyzed the data	Formal analysis	YES
4406536	25902264	GQZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Revised the manuscript draft	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406536	25902264	GQZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Revised the manuscript draft	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406536	25902264	GQZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Revised the manuscript draft	Revised the manuscript draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4406536	25902264	LJC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406536	25902264	MHL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Revised the manuscript draft	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406536	25902264	MHL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Revised the manuscript draft	Performed the experiments	Performed the experiments	Investigation	YES
4406536	25902264	MHL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Revised the manuscript draft	Analyzed the data	Analyzed the data	Formal analysis	YES
4406536	25902264	MHL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Revised the manuscript draft	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406536	25902264	MHL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Revised the manuscript draft	Revised the manuscript draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4406536	25902264	SRL	PLoS5	Conceived and designed the experiments|Revised the manuscript draft	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406536	25902264	SRL	PLoS5	Conceived and designed the experiments|Revised the manuscript draft	Revised the manuscript draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4406536	25902264	YYS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406536	25902264	ZJL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Revised the manuscript draft	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406536	25902264	ZJL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Revised the manuscript draft	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406536	25902264	ZJL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Revised the manuscript draft	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406536	25902264	ZJL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Revised the manuscript draft	Revised the manuscript draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5767899	29348913	AG	7	Statistical analyses	Statistical analyses	Analyzed the data	Formal analysis	YES
5767899	29348913	FD	7	Data collection	Data collection	Performed the experiments	Investigation	YES
5767899	29348913	MM	7	Study design	Study design	Conceived and designed the experiments	Methodology	YES
5767899	29348913	MS	7	Surgeon	Surgeon	-	-	NO
5767899	29348913	OG	7	Writer and surgeon	Writer and surgeon	Wrote the paper	-	YES
5767899	29348913	SM	7	Data collection	Data collection	Performed the experiments	Investigation	YES
3893751	24490077	Anita Ringberg	2	helped with the interpretation of the results and with drafting the paper	helped with the interpretation of the results and with drafting the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3893751	24490077	Carl Blomqvist	2	helped with the interpretation of the results and with drafting the paper	helped with the interpretation of the results and with drafting the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3893751	24490077	Christine Johansson	2	were involved in pathology review and scoring of stains and contributed substantially to paper editing	were involved in pathology review and scoring of stains and contributed substantially to paper editing	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
3893751	24490077	Fredrik Warnberg	2	designed the overall study, compiled and curated the datasets, coordinated the study, and helped draft and finalize the paper	designed the overall study, compiled and curated the datasets, coordinated the study, and helped draft and finalize the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Data curation|Methodology|Project administration|Writing - Original Draft|Writing - Review & Editing	YES
3893751	24490077	Rose-Marie Amini	2	were involved in pathology review and scoring of stains and contributed substantially to paper editing	were involved in pathology review and scoring of stains and contributed substantially to paper editing	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
3893751	24490077	SISH	2	staining from the tmas and helped provide expertise in breast cancer pathology	staining from the tmas and helped provide expertise in breast cancer pathology	Performed the experiments	Investigation	YES
3893751	24490077	Wenjing Zhou	2	was responsible for data analyses, and paper preparation and editing|were involved in pathology review and scoring of stains and contributed substantially to paper editing	was responsible for data analyses, and paper preparation and editing	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
3893751	24490077	Wenjing Zhou	2	was responsible for data analyses, and paper preparation and editing|were involved in pathology review and scoring of stains and contributed substantially to paper editing	were involved in pathology review and scoring of stains and contributed substantially to paper editing	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5563362	28868060	HL	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5563362	28868060	JL	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5563362	28868060	JW	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5563362	28868060	PZ	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5563362	28868060	ZN	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5016494	27609782	AMF	2	oversaw early development of the model|made additions to the manuscript	oversaw early development of the model	Performed the experiments	Methodology|Supervision	YES
5016494	27609782	AMF	2	oversaw early development of the model|made additions to the manuscript	made additions to the manuscript	-	-	NO
5016494	27609782	FT-P	2	provided input on efficiency estimation	provided input on efficiency estimation	Analyzed the data	Formal analysis	YES
5016494	27609782	FTP	2	made additions to the manuscript	made additions to the manuscript	-	-	NO
5016494	27609782	HJP	2	constructed and parameterized the dynamic model|made additions to the manuscript	constructed and parameterized the dynamic model	Performed the experiments	Investigation|Methodology	YES
5016494	27609782	HJP	2	constructed and parameterized the dynamic model|made additions to the manuscript	made additions to the manuscript	-	-	NO
5016494	27609782	KMM	2	designed the overall modelling study|constructed and parameterized the dynamic model|analyzed the dynamic model|wrote the first draft of the manuscript	designed the overall modelling study	Conceived and designed the experiments|Performed the experiments	Methodology	YES
5016494	27609782	KMM	2	designed the overall modelling study|constructed and parameterized the dynamic model|analyzed the dynamic model|wrote the first draft of the manuscript	constructed and parameterized the dynamic model	Performed the experiments	Investigation|Methodology	YES
5016494	27609782	KMM	2	designed the overall modelling study|constructed and parameterized the dynamic model|analyzed the dynamic model|wrote the first draft of the manuscript	analyzed the dynamic model	Performed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5016494	27609782	KMM	2	designed the overall modelling study|constructed and parameterized the dynamic model|analyzed the dynamic model|wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
5016494	27609782	MCB	2	designed additional model analyses|critically revised the manuscript	designed additional model analyses	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5016494	27609782	MCB	2	designed additional model analyses|critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5016494	27609782	PV	2	designed the overall modelling study|critically revised the manuscript	designed the overall modelling study	Conceived and designed the experiments|Performed the experiments	Methodology	YES
5016494	27609782	PV	2	designed the overall modelling study|critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5016494	27609782	RW	2	provided data|made additions to the manuscript	provided data	Contributed reagents/materials/analysis tools	Resources	YES
5016494	27609782	RW	2	provided data|made additions to the manuscript	made additions to the manuscript	-	-	NO
5016494	27609782	SI	2	provided data	provided data	Contributed reagents/materials/analysis tools	Resources	YES
5016494	27609782	SPR	2	provided data	provided data	Contributed reagents/materials/analysis tools	Resources	YES
5316208	28212614	LSW	2	conceived and designed the experimental plan, analysed and interpreted the sequence data, and drafted the manuscript	conceived and designed the experimental plan, analysed and interpreted the sequence data, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5316208	28212614	LY	2	performed the experiments and analysed the sequence data	performed the experiments and analysed the sequence data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5316208	28212614	SRF	2	performed the experiments and analysed the sequence data	performed the experiments and analysed the sequence data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6306779	30326642	A.M.	CRediT	formal analysis	formal analysis	Analyzed the data	Formal analysis	YES
6306779	30326642	G.M.P.	CRediT	formal analysis|writing--review and editing	formal analysis	Analyzed the data	Formal analysis	YES
6306779	30326642	G.M.P.	CRediT	formal analysis|writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6306779	30326642	K.B.	CRediT	methodology|project administration	methodology	Performed the experiments	Methodology	YES
6306779	30326642	K.B.	CRediT	methodology|project administration	project administration	-	Project administration	YES
6306779	30326642	L.S.D.	CRediT	conceptualization|methodology|formal analysis|writing--original draft preparation|writing--review and editing|funding acquisition	conceptualization	Conceived and designed the experiments	Conceptualization	YES
6306779	30326642	L.S.D.	CRediT	conceptualization|methodology|formal analysis|writing--original draft preparation|writing--review and editing|funding acquisition	methodology	Performed the experiments	Methodology	YES
6306779	30326642	L.S.D.	CRediT	conceptualization|methodology|formal analysis|writing--original draft preparation|writing--review and editing|funding acquisition	formal analysis	Analyzed the data	Formal analysis	YES
6306779	30326642	L.S.D.	CRediT	conceptualization|methodology|formal analysis|writing--original draft preparation|writing--review and editing|funding acquisition	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6306779	30326642	L.S.D.	CRediT	conceptualization|methodology|formal analysis|writing--original draft preparation|writing--review and editing|funding acquisition	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6306779	30326642	L.S.D.	CRediT	conceptualization|methodology|formal analysis|writing--original draft preparation|writing--review and editing|funding acquisition	funding acquisition	-	Funding acquisition	YES
6306779	30326642	M.N.	CRediT	conceptualization|methodology|writing--review and editing|project administration|funding acquisition	conceptualization	Conceived and designed the experiments	Conceptualization	YES
6306779	30326642	M.N.	CRediT	conceptualization|methodology|writing--review and editing|project administration|funding acquisition	methodology	Performed the experiments	Methodology	YES
6306779	30326642	M.N.	CRediT	conceptualization|methodology|writing--review and editing|project administration|funding acquisition	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6306779	30326642	M.N.	CRediT	conceptualization|methodology|writing--review and editing|project administration|funding acquisition	project administration	-	Project administration	YES
6306779	30326642	M.N.	CRediT	conceptualization|methodology|writing--review and editing|project administration|funding acquisition	funding acquisition	-	Funding acquisition	YES
6306779	30326642	R.S.	CRediT	writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6306779	30326642	S.K.	CRediT	conceptualization|methodology|formal analysis|supervision|writing--review and editing|project administration|funding acquisition	conceptualization	Conceived and designed the experiments	Conceptualization	YES
6306779	30326642	S.K.	CRediT	conceptualization|methodology|formal analysis|supervision|writing--review and editing|project administration|funding acquisition	methodology	Performed the experiments	Methodology	YES
6306779	30326642	S.K.	CRediT	conceptualization|methodology|formal analysis|supervision|writing--review and editing|project administration|funding acquisition	formal analysis	Analyzed the data	Formal analysis	YES
6306779	30326642	S.K.	CRediT	conceptualization|methodology|formal analysis|supervision|writing--review and editing|project administration|funding acquisition	supervision	-	Supervision	YES
6306779	30326642	S.K.	CRediT	conceptualization|methodology|formal analysis|supervision|writing--review and editing|project administration|funding acquisition	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6306779	30326642	S.K.	CRediT	conceptualization|methodology|formal analysis|supervision|writing--review and editing|project administration|funding acquisition	project administration	-	Project administration	YES
6306779	30326642	S.K.	CRediT	conceptualization|methodology|formal analysis|supervision|writing--review and editing|project administration|funding acquisition	funding acquisition	-	Funding acquisition	YES
5771967	29387384	Ali Akbar Khasseh	1	Data collection|Data interpretation	Data collection	Performed the experiments	Investigation	YES
5771967	29387384	Ali Akbar Khasseh	1	Data collection|Data interpretation	Data interpretation	Analyzed the data	Formal analysis	YES
5771967	29387384	Hajar Ziaei Hezarjaribi	1	Data interpretation	Data interpretation	Analyzed the data	Formal analysis	YES
5771967	29387384	Mahdi Fakhar	1	Study concept|Data interpretation|Writing the paper	Study concept	Conceived and designed the experiments	Conceptualization	YES
5771967	29387384	Mahdi Fakhar	1	Study concept|Data interpretation|Writing the paper	Data interpretation	Analyzed the data	Formal analysis	YES
5771967	29387384	Mahdi Fakhar	1	Study concept|Data interpretation|Writing the paper	Writing the paper	Wrote the paper	Writing - Original Draft	YES
5771967	29387384	Masoud Soosaraei	1	Data collection|Data interpretation|Writing the paper	Data collection	Performed the experiments	Investigation	YES
5771967	29387384	Masoud Soosaraei	1	Data collection|Data interpretation|Writing the paper	Data interpretation	Analyzed the data	Formal analysis	YES
5771967	29387384	Masoud Soosaraei	1	Data collection|Data interpretation|Writing the paper	Writing the paper	Wrote the paper	Writing - Original Draft	YES
4406550	25901753	JO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406550	25901753	JO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406550	25901753	JO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406550	25901753	JO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406550	25901753	JO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406550	25901753	TB	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406550	25901753	TB	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4406550	25901753	TB	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406550	25901753	TMI	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406550	25901753	TMI	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406550	25901753	TMI	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406550	25901753	TMI	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5911172	29736104	All the authors	2	have contributed in the design, revision and final version to be published equally and they are qualified to be reported as authors	have contributed in the design, revision and final version to be published equally and they are qualified to be reported as authors	Conceived and designed the experiments|Wrote the paper	Writing - Review & Editing	YES
5832643	29511540	AF	7	data analysis	data analysis	Analyzed the data	Formal analysis	YES
5832643	29511540	AS	7	writing paper	writing paper	Wrote the paper	Writing - Original Draft	YES
5832643	29511540	CR	7	data collection	data collection	Performed the experiments	Investigation	YES
5832643	29511540	JB	7	data collection	data collection	Performed the experiments	Investigation	YES
5832643	29511540	NF	7	data collection, writing paper	data collection, writing paper	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5832643	29511540	NW	7	study concept	study concept	Conceived and designed the experiments	Conceptualization	YES
5832643	29511540	VK	7	writing paper, data analysis	writing paper, data analysis	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6306781	30501076	C.L.	CRediT	Conceptualization|Formal analysis|Investigation|Resources|Data curation|Writing-original draft preparation	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6306781	30501076	C.L.	CRediT	Conceptualization|Formal analysis|Investigation|Resources|Data curation|Writing-original draft preparation	Formal analysis	Analyzed the data	Formal analysis	YES
6306781	30501076	C.L.	CRediT	Conceptualization|Formal analysis|Investigation|Resources|Data curation|Writing-original draft preparation	Investigation	Performed the experiments	Investigation	YES
6306781	30501076	C.L.	CRediT	Conceptualization|Formal analysis|Investigation|Resources|Data curation|Writing-original draft preparation	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6306781	30501076	C.L.	CRediT	Conceptualization|Formal analysis|Investigation|Resources|Data curation|Writing-original draft preparation	Data curation	Analyzed the data	Data curation	YES
6306781	30501076	C.L.	CRediT	Conceptualization|Formal analysis|Investigation|Resources|Data curation|Writing-original draft preparation	Writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
6306781	30501076	J.B.	CRediT	Conceptualization|Methodology|Formal analysis|Resources|Writing-original draft preparation|Writing-review & editing|Supervision	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6306781	30501076	J.B.	CRediT	Conceptualization|Methodology|Formal analysis|Resources|Writing-original draft preparation|Writing-review & editing|Supervision	Methodology	Performed the experiments	Methodology	YES
6306781	30501076	J.B.	CRediT	Conceptualization|Methodology|Formal analysis|Resources|Writing-original draft preparation|Writing-review & editing|Supervision	Formal analysis	Analyzed the data	Formal analysis	YES
6306781	30501076	J.B.	CRediT	Conceptualization|Methodology|Formal analysis|Resources|Writing-original draft preparation|Writing-review & editing|Supervision	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6306781	30501076	J.B.	CRediT	Conceptualization|Methodology|Formal analysis|Resources|Writing-original draft preparation|Writing-review & editing|Supervision	Writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
6306781	30501076	J.B.	CRediT	Conceptualization|Methodology|Formal analysis|Resources|Writing-original draft preparation|Writing-review & editing|Supervision	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6306781	30501076	J.B.	CRediT	Conceptualization|Methodology|Formal analysis|Resources|Writing-original draft preparation|Writing-review & editing|Supervision	Supervision	-	Supervision	YES
6306781	30501076	O.B.	CRediT	Conceptualization|Resources|Supervision	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6306781	30501076	O.B.	CRediT	Conceptualization|Resources|Supervision	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6306781	30501076	O.B.	CRediT	Conceptualization|Resources|Supervision	Supervision	-	Supervision	YES
3913086	24527216	All authors	2	contributed to the paper	contributed to the paper	-	-	NO
3913086	24527216	David Houghton	2	contributed to the concept and design of the study	contributed to the concept and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3913086	24527216	Ian Keary	2	contributed to the concept and design of the study	contributed to the concept and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3913086	24527216	Neville Davidson	2	contributed to the concept and design of the study|undertook the clinical interpretation of the results	contributed to the concept and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3913086	24527216	Neville Davidson	2	contributed to the concept and design of the study|undertook the clinical interpretation of the results	undertook the clinical interpretation of the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3913086	24527216	Teresa Camburn	2	extracted and collated the patient record data|undertook the clinical interpretation of the results	extracted and collated the patient record data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
3913086	24527216	Teresa Camburn	2	extracted and collated the patient record data|undertook the clinical interpretation of the results	undertook the clinical interpretation of the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6306786	30501035	A.J.A.	CRediT	Conceptualization|Writing--review & editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6306786	30501035	A.J.A.	CRediT	Conceptualization|Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6306786	30501035	K.M.	CRediT	Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6306786	30501035	S.P.D.	CRediT	Conceptualization|Writing--review & editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6306786	30501035	S.P.D.	CRediT	Conceptualization|Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
5022114	27624144	All authors	2	have made substantial contributions to conception and design, acquisition of data, or analysis and interpretation of data	have made substantial contributions to conception and design, acquisition of data, or analysis and interpretation of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
4406551	25901959	BG	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406551	25901959	BG	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406551	25901959	MZ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406551	25901959	MZ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406551	25901959	XL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406551	25901959	XL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406551	25901959	XL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406551	25901959	XL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406551	25901959	XL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406551	25901959	YY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406551	25901959	YY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406551	25901959	YY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406551	25901959	YY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406551	25901959	YY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4499637	26221587	Deok-Won Lee	2	contributed equally to this work	contributed equally to this work	-	-	NO
4499637	26221587	Sung Eun Kim	2	contributed equally to this work	contributed equally to this work	-	-	NO
4499637	26221587	Young-Pil Yun	2	contributed equally to this work	contributed equally to this work	-	-	NO
5563363	28868056	CH	PLoS5	Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5563363	28868056	DS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5563363	28868056	JC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5563363	28868056	JG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5563363	28868056	JG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
5563363	28868056	JG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5563363	28868056	JL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5563363	28868056	PG	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5563363	28868056	SC	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5563363	28868056	WS	PLoS5	Performed the experiments|Analyzed the data|Wrote the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
5563363	28868056	WS	PLoS5	Performed the experiments|Analyzed the data|Wrote the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
5563363	28868056	WS	PLoS5	Performed the experiments|Analyzed the data|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5563363	28868056	XC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5563363	28868056	XY	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5563363	28868056	XZ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5563363	28868056	YX	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5563363	28868056	YZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5563363	28868056	ZZ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5316211	28212624	AC	2	helped to draft the discussion|helped to interpret data	helped to draft the discussion	Wrote the paper	Writing - Original Draft	YES
5316211	28212624	AC	2	helped to draft the discussion|helped to interpret data	helped to interpret data	Analyzed the data	Formal analysis	YES
5316211	28212624	All authors	2	reviewed the manuscript and approved the final version	reviewed the manuscript and approved the final version	Wrote the paper	Writing - Review & Editing	YES
5316211	28212624	CR	2	helped to interpret data	helped to interpret data	Analyzed the data	Formal analysis	YES
5316211	28212624	EB	2	helped to interpret data	helped to interpret data	Analyzed the data	Formal analysis	YES
5316211	28212624	JML	2	carried out the metabolome pre-processing and the metabolome multivariate analysis using open-source software	carried out the metabolome pre-processing and the metabolome multivariate analysis using open-source software	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5316211	28212624	LLM	2	helped to interpret data	helped to interpret data	Analyzed the data	Formal analysis	YES
5316211	28212624	MM	2	helped to interpret data	helped to interpret data	Analyzed the data	Formal analysis	YES
5316211	28212624	NMR	2	spectroscopy data	spectroscopy data	Performed the experiments	Investigation	YES
5316211	28212624	RNome	2	statistical and functional analysis, created the figures and wrote the main manuscript text	statistical and functional analysis, created the figures and wrote the main manuscript text	Analyzed the data|Wrote the paper	Formal analysis|Visualization|Writing - Original Draft	YES
5316211	28212624	YRC	2	designed and carried out the rif analysis and the multiple factor analysis|helped to interpret data	designed and carried out the rif analysis and the multiple factor analysis	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5316211	28212624	YRC	2	designed and carried out the rif analysis and the multiple factor analysis|helped to interpret data	helped to interpret data	Analyzed the data	Formal analysis	YES
6306803	30477233	G.R.	PLoS52	performed some of the interviews	performed some of the interviews	Performed the experiments	Investigation	YES
6306803	30477233	K.I.	PLoS52	conceived and designed the research|wrote the paper	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
6306803	30477233	K.I.	PLoS52	conceived and designed the research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6306803	30477233	O.D.	PLoS52	performed some of the interviews	performed some of the interviews	Performed the experiments	Investigation	YES
6306803	30477233	P.D.	PLoS52	conceived and designed the research|wrote the paper	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
6306803	30477233	P.D.	PLoS52	conceived and designed the research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6306803	30477233	all authors	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5911173	29736095	Majid Malekzadeh Shafaroudi	2	contribution to design, preparing and diagnosing the histologic samples	contribution to design, preparing and diagnosing the histologic samples	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5911173	29736095	Mazaher Gholipourmalekabad	2	contribution toacquisition, analysis and interpretation of data	contribution toacquisition, analysis and interpretation of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5911173	29736095	Nourollah Rezaei	2	contribution to acquisition, statistical analysis, drafting the article, provided endnote, final modification and submitted the article	contribution to acquisition, statistical analysis, drafting the article, provided endnote, final modification and submitted the article	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5023853	27630096	AS	2	made substantial contributions to the design and conceptualization of the study|were involved in tool development and data acquisition|were involved in analysis and interpretation of the data|were involved in drafting of the manuscript and revising it	made substantial contributions to the design and conceptualization of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5023853	27630096	AS	2	made substantial contributions to the design and conceptualization of the study|were involved in tool development and data acquisition|were involved in analysis and interpretation of the data|were involved in drafting of the manuscript and revising it	were involved in tool development and data acquisition	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5023853	27630096	AS	2	made substantial contributions to the design and conceptualization of the study|were involved in tool development and data acquisition|were involved in analysis and interpretation of the data|were involved in drafting of the manuscript and revising it	were involved in analysis and interpretation of the data	Analyzed the data	Formal analysis	YES
5023853	27630096	AS	2	made substantial contributions to the design and conceptualization of the study|were involved in tool development and data acquisition|were involved in analysis and interpretation of the data|were involved in drafting of the manuscript and revising it	were involved in drafting of the manuscript and revising it	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5023853	27630096	FC	2	were involved in drafting of the manuscript and revising it	were involved in drafting of the manuscript and revising it	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5023853	27630096	GM	2	made substantial contributions to the design and conceptualization of the study|were involved in analysis and interpretation of the data|were involved in drafting of the manuscript and revising it	made substantial contributions to the design and conceptualization of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5023853	27630096	GM	2	made substantial contributions to the design and conceptualization of the study|were involved in analysis and interpretation of the data|were involved in drafting of the manuscript and revising it	were involved in analysis and interpretation of the data	Analyzed the data	Formal analysis	YES
5023853	27630096	GM	2	made substantial contributions to the design and conceptualization of the study|were involved in analysis and interpretation of the data|were involved in drafting of the manuscript and revising it	were involved in drafting of the manuscript and revising it	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5023853	27630096	JB	2	were involved in tool development and data acquisition	were involved in tool development and data acquisition	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5023853	27630096	PS	2	were involved in analysis and interpretation of the data|were involved in drafting of the manuscript and revising it	were involved in analysis and interpretation of the data	Analyzed the data	Formal analysis	YES
5023853	27630096	PS	2	were involved in analysis and interpretation of the data|were involved in drafting of the manuscript and revising it	were involved in drafting of the manuscript and revising it	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5023853	27630096	PVS	2	were involved in tool development and data acquisition	were involved in tool development and data acquisition	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5023853	27630096	RB	2	were involved in tool development and data acquisition	were involved in tool development and data acquisition	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5023853	27630096	SKM	2	made substantial contributions to the design and conceptualization of the study	made substantial contributions to the design and conceptualization of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5023853	27630096	SM	2	made substantial contributions to the design and conceptualization of the study	made substantial contributions to the design and conceptualization of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3654290	23690745	H. M. Bjorgaas	2	has contributed to the study design, collection of data, and writing the paper	has contributed to the study design, collection of data, and writing the paper	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Methodology|Resources|Writing - Original Draft	YES
3654290	23690745	I. Elgen	2	has contributed to the study design, draft, and revision of the paper	has contributed to the study design, draft, and revision of the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft|Writing - Review & Editing	YES
3654290	23690745	M. Hysing	2	has contributed to data analysis, draft, and revision of the paper	has contributed to data analysis, draft, and revision of the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
3654290	23690745	T. Boe	2	has contributed to the statistical analysis, draft, and revision of the paper	has contributed to the statistical analysis, draft, and revision of the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5832646	29511536	Masood Umer	7	study design, writing	study design, writing	Conceived and designed the experiments|Wrote the paper	Methodology	YES
5832646	29511536	Muhammed Atif	7	writing	writing	Wrote the paper	-	YES
5832646	29511536	Muhammed Nazim	7	writing	writing	Wrote the paper	-	YES
5832646	29511536	Yasir Mohib	7	study design, writing	study design, writing	Conceived and designed the experiments|Wrote the paper	Methodology	YES
4406552	25902061	DP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406552	25902061	DP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406552	25902061	DP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406552	25902061	GA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Reconducted the papers statistical analysis using non-parametric methods	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406552	25902061	GA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Reconducted the papers statistical analysis using non-parametric methods	Performed the experiments	Performed the experiments	Investigation	YES
4406552	25902061	GA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Reconducted the papers statistical analysis using non-parametric methods	Analyzed the data	Analyzed the data	Formal analysis	YES
4406552	25902061	GA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Reconducted the papers statistical analysis using non-parametric methods	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406552	25902061	GA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Reconducted the papers statistical analysis using non-parametric methods	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406552	25902061	GA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Reconducted the papers statistical analysis using non-parametric methods	Reconducted the papers statistical analysis using non-parametric methods	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4406552	25902061	JS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406552	25902061	JS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406552	25902061	LAS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Reconducted the papers statistical analysis using non-parametric methods	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406552	25902061	LAS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Reconducted the papers statistical analysis using non-parametric methods	Performed the experiments	Performed the experiments	Investigation	YES
4406552	25902061	LAS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Reconducted the papers statistical analysis using non-parametric methods	Analyzed the data	Analyzed the data	Formal analysis	YES
4406552	25902061	LAS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Reconducted the papers statistical analysis using non-parametric methods	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406552	25902061	LAS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Reconducted the papers statistical analysis using non-parametric methods	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406552	25902061	LAS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Reconducted the papers statistical analysis using non-parametric methods	Reconducted the papers statistical analysis using non-parametric methods	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4406552	25902061	LJL	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406552	25902061	LJL	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406552	25902061	OE	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Reconducted the papers statistical analysis using non-parametric methods	Analyzed the data	Analyzed the data	Formal analysis	YES
4406552	25902061	OE	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Reconducted the papers statistical analysis using non-parametric methods	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406552	25902061	OE	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Reconducted the papers statistical analysis using non-parametric methods	Reconducted the papers statistical analysis using non-parametric methods	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4406552	25902061	SSJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406552	25902061	SSJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406552	25902061	SSJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406552	25902061	SSJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6306811	30274311	C.N.	CRediT	Conceptualization|Methodology|Software|Validation|Formal analysis|Investigation|Resources|Data curation|Writing--original draft preparation|Writing--review & editing|Visualization|Supervision|Project administration	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6306811	30274311	C.N.	CRediT	Conceptualization|Methodology|Software|Validation|Formal analysis|Investigation|Resources|Data curation|Writing--original draft preparation|Writing--review & editing|Visualization|Supervision|Project administration	Methodology	Performed the experiments	Methodology	YES
6306811	30274311	C.N.	CRediT	Conceptualization|Methodology|Software|Validation|Formal analysis|Investigation|Resources|Data curation|Writing--original draft preparation|Writing--review & editing|Visualization|Supervision|Project administration	Software	Contributed reagents/materials/analysis tools	Software	YES
6306811	30274311	C.N.	CRediT	Conceptualization|Methodology|Software|Validation|Formal analysis|Investigation|Resources|Data curation|Writing--original draft preparation|Writing--review & editing|Visualization|Supervision|Project administration	Validation	Performed the experiments	Validation	YES
6306811	30274311	C.N.	CRediT	Conceptualization|Methodology|Software|Validation|Formal analysis|Investigation|Resources|Data curation|Writing--original draft preparation|Writing--review & editing|Visualization|Supervision|Project administration	Formal analysis	Analyzed the data	Formal analysis	YES
6306811	30274311	C.N.	CRediT	Conceptualization|Methodology|Software|Validation|Formal analysis|Investigation|Resources|Data curation|Writing--original draft preparation|Writing--review & editing|Visualization|Supervision|Project administration	Investigation	Performed the experiments	Investigation	YES
6306811	30274311	C.N.	CRediT	Conceptualization|Methodology|Software|Validation|Formal analysis|Investigation|Resources|Data curation|Writing--original draft preparation|Writing--review & editing|Visualization|Supervision|Project administration	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6306811	30274311	C.N.	CRediT	Conceptualization|Methodology|Software|Validation|Formal analysis|Investigation|Resources|Data curation|Writing--original draft preparation|Writing--review & editing|Visualization|Supervision|Project administration	Data curation	Analyzed the data	Data curation	YES
6306811	30274311	C.N.	CRediT	Conceptualization|Methodology|Software|Validation|Formal analysis|Investigation|Resources|Data curation|Writing--original draft preparation|Writing--review & editing|Visualization|Supervision|Project administration	Writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6306811	30274311	C.N.	CRediT	Conceptualization|Methodology|Software|Validation|Formal analysis|Investigation|Resources|Data curation|Writing--original draft preparation|Writing--review & editing|Visualization|Supervision|Project administration	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6306811	30274311	C.N.	CRediT	Conceptualization|Methodology|Software|Validation|Formal analysis|Investigation|Resources|Data curation|Writing--original draft preparation|Writing--review & editing|Visualization|Supervision|Project administration	Visualization	Analyzed the data	Visualization	YES
6306811	30274311	C.N.	CRediT	Conceptualization|Methodology|Software|Validation|Formal analysis|Investigation|Resources|Data curation|Writing--original draft preparation|Writing--review & editing|Visualization|Supervision|Project administration	Supervision	-	Supervision	YES
6306811	30274311	C.N.	CRediT	Conceptualization|Methodology|Software|Validation|Formal analysis|Investigation|Resources|Data curation|Writing--original draft preparation|Writing--review & editing|Visualization|Supervision|Project administration	Project administration	-	Project administration	YES
6306811	30274311	J.C.	CRediT	Methodology|Resources|Writing--review & editing	Methodology	Performed the experiments	Methodology	YES
6306811	30274311	J.C.	CRediT	Methodology|Resources|Writing--review & editing	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6306811	30274311	J.C.	CRediT	Methodology|Resources|Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6306811	30274311	L.-W.C.	CRediT	Validation|Formal analysis|Writing--original draft preparation|Writing--review & editing|Visualization	Validation	Performed the experiments	Validation	YES
6306811	30274311	L.-W.C.	CRediT	Validation|Formal analysis|Writing--original draft preparation|Writing--review & editing|Visualization	Formal analysis	Analyzed the data	Formal analysis	YES
6306811	30274311	L.-W.C.	CRediT	Validation|Formal analysis|Writing--original draft preparation|Writing--review & editing|Visualization	Writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6306811	30274311	L.-W.C.	CRediT	Validation|Formal analysis|Writing--original draft preparation|Writing--review & editing|Visualization	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6306811	30274311	L.-W.C.	CRediT	Validation|Formal analysis|Writing--original draft preparation|Writing--review & editing|Visualization	Visualization	Analyzed the data	Visualization	YES
5319016	28222695	JZ	PLoS52	conceived and designed the experiments|performed the experiments|performed data analysis|drafted the manuscript|revised the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5319016	28222695	JZ	PLoS52	conceived and designed the experiments|performed the experiments|performed data analysis|drafted the manuscript|revised the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5319016	28222695	JZ	PLoS52	conceived and designed the experiments|performed the experiments|performed data analysis|drafted the manuscript|revised the manuscript	performed data analysis	Analyzed the data	Formal analysis	YES
5319016	28222695	JZ	PLoS52	conceived and designed the experiments|performed the experiments|performed data analysis|drafted the manuscript|revised the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5319016	28222695	JZ	PLoS52	conceived and designed the experiments|performed the experiments|performed data analysis|drafted the manuscript|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5319016	28222695	LW	PLoS52	performed data analysis	performed data analysis	Analyzed the data	Formal analysis	YES
5319016	28222695	QY	PLoS52	provided materials and references	provided materials and references	Contributed reagents/materials/analysis tools	Resources	YES
5319016	28222695	QZ	PLoS52	performed the experiments|performed data analysis	performed the experiments	Performed the experiments	Investigation	YES
5319016	28222695	QZ	PLoS52	performed the experiments|performed data analysis	performed data analysis	Analyzed the data	Formal analysis	YES
5319016	28222695	RM	PLoS52	provided materials and references	provided materials and references	Contributed reagents/materials/analysis tools	Resources	YES
5319016	28222695	WH	PLoS52	performed the experiments|performed data analysis	performed the experiments	Performed the experiments	Investigation	YES
5319016	28222695	WH	PLoS52	performed the experiments|performed data analysis	performed data analysis	Analyzed the data	Formal analysis	YES
5319016	28222695	XH	PLoS52	performed data analysis	performed data analysis	Analyzed the data	Formal analysis	YES
5319016	28222695	XZ	PLoS52	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5319016	28222695	YC	PLoS52	conceived and designed the experiments|performed the experiments|performed data analysis|drafted the manuscript|revised the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5319016	28222695	YC	PLoS52	conceived and designed the experiments|performed the experiments|performed data analysis|drafted the manuscript|revised the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5319016	28222695	YC	PLoS52	conceived and designed the experiments|performed the experiments|performed data analysis|drafted the manuscript|revised the manuscript	performed data analysis	Analyzed the data	Formal analysis	YES
5319016	28222695	YC	PLoS52	conceived and designed the experiments|performed the experiments|performed data analysis|drafted the manuscript|revised the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5319016	28222695	YC	PLoS52	conceived and designed the experiments|performed the experiments|performed data analysis|drafted the manuscript|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5563368	28868059	All authors	2	contributed to and approved the final manuscript	contributed to and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5563368	28868059	C-HC	2	performed the network component analysis	performed the network component analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5563368	28868059	C-WL	2	analyzed the data and wrote the manuscript|contributed equally as first author|performed the network component analysis	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5563368	28868059	C-WL	2	analyzed the data and wrote the manuscript|contributed equally as first author|performed the network component analysis	contributed equally as first author	-	-	NO
5563368	28868059	C-WL	2	analyzed the data and wrote the manuscript|contributed equally as first author|performed the network component analysis	performed the network component analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5563368	28868059	C-YC	2	performed the rna experiment and pcr analysis	performed the rna experiment and pcr analysis	Performed the experiments	Investigation	YES
5563368	28868059	H-JH	2	provided the technical assistance|organized this work	provided the technical assistance	Performed the experiments	Investigation	YES
5563368	28868059	H-JH	2	provided the technical assistance|organized this work	organized this work	-	-	NO
5563368	28868059	L-YH	2	analyzed the data and wrote the manuscript|contributed equally as first author|performed the rna experiment and pcr analysis|performed the network component analysis	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5563368	28868059	L-YH	2	analyzed the data and wrote the manuscript|contributed equally as first author|performed the rna experiment and pcr analysis|performed the network component analysis	contributed equally as first author	-	-	NO
5563368	28868059	L-YH	2	analyzed the data and wrote the manuscript|contributed equally as first author|performed the rna experiment and pcr analysis|performed the network component analysis	performed the rna experiment and pcr analysis	Performed the experiments	Investigation	YES
5563368	28868059	L-YH	2	analyzed the data and wrote the manuscript|contributed equally as first author|performed the rna experiment and pcr analysis|performed the network component analysis	performed the network component analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5563368	28868059	R-HL	2	contributed equally as first author|provided the technical assistance	contributed equally as first author	-	-	NO
5563368	28868059	R-HL	2	contributed equally as first author|provided the technical assistance	provided the technical assistance	Performed the experiments	Investigation	YES
5563368	28868059	Y-CW	2	performed the rna experiment and pcr analysis	performed the rna experiment and pcr analysis	Performed the experiments	Investigation	YES
5026729	27637172	AS	2	performed laboratory evaluations and assisted in their interpretation	performed laboratory evaluations and assisted in their interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5026729	27637172	All authors	2	reviewed this manuscript, provided feedback and approved the manuscript in its final form	reviewed this manuscript, provided feedback and approved the manuscript in its final form	Wrote the paper	Writing - Review & Editing	YES
5026729	27637172	IS	2	performed laboratory evaluations and assisted in their interpretation	performed laboratory evaluations and assisted in their interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5026729	27637172	JA	2	conceived of the analysis, contributed to its design, assisted in the interpretation of results and provided project oversight	conceived of the analysis, contributed to its design, assisted in the interpretation of results and provided project oversight	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology|Supervision	YES
5026729	27637172	JF	2	contributed to the analytic design and collected clinical data	contributed to the analytic design and collected clinical data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5026729	27637172	NM	2	assisted in the interpretation of the analysis and provided project oversight	assisted in the interpretation of the analysis and provided project oversight	Analyzed the data	Formal analysis|Supervision	YES
5026729	27637172	Nicolas Chomont	2	performed laboratory evaluations and assisted in their interpretation	performed laboratory evaluations and assisted in their interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5026729	27637172	Nitiya Chomchey	2	collected clinical data	collected clinical data	Performed the experiments	Investigation	YES
5026729	27637172	RD	2	performed laboratory evaluations and assisted in their interpretation	performed laboratory evaluations and assisted in their interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5026729	27637172	RR	2	conducted colon biopsies	conducted colon biopsies	Performed the experiments	Investigation	YES
5026729	27637172	SK	2	performed laboratory evaluations and assisted in their interpretation	performed laboratory evaluations and assisted in their interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5026729	27637172	TC	2	designed this analysis and authored the first draft of the manuscript	designed this analysis and authored the first draft of the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
5911174	29736101	Kaveh B. Kelarestaghi	2	performed statistical analyses	performed statistical analyses	Analyzed the data	Formal analysis	YES
4406553	25902069	CS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406553	25902069	CS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406553	25902069	CS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406553	25902069	CS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406553	25902069	DWK	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406553	25902069	DWK	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406553	25902069	DWK	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406553	25902069	HKO	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406553	25902069	HKO	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406553	25902069	HKO	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406553	25902069	HKO	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406553	25902069	IAK	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406553	25902069	IAK	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406553	25902069	JHK	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406553	25902069	JHK	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406553	25902069	JHK	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406553	25902069	JSK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406553	25902069	JSK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406553	25902069	JSK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406553	25902069	JSK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406553	25902069	JSK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406553	25902069	KWL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406553	25902069	KWL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406553	25902069	KWL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406553	25902069	KYE	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406553	25902069	KYE	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406553	25902069	KYE	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406553	25902069	SBK	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406553	25902069	SBK	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406553	25902069	SBK	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406553	25902069	SBK	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406553	25902069	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406553	25902069	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406553	25902069	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406553	25902069	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5832648	29511539	A. Hecker	1	Writing the paper & data collection	Writing the paper & data collection	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5832648	29511539	Christian Koch	1	Writing the paper & data collection	Writing the paper & data collection	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5832648	29511539	Emmanuel Schneck	1	Writing the paper & data collection	Writing the paper & data collection	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5832648	29511539	M. Sander	1	Writing the paper & data collection	Writing the paper & data collection	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5832648	29511539	R. Horbelt	1	Writing the paper & data collection	Writing the paper & data collection	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5832648	29511539	Thomas S. Zajonz	1	Writing the paper & data collection	Writing the paper & data collection	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5832648	29511539	W. Padberg	1	Writing the paper & data collection	Writing the paper & data collection	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6306812	30400619	R.M.E.	2	who assisted me in designing the methodology and data analysis	who assisted me in designing the methodology and data analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Methodology	YES
6306812	30400619	S.Q.J.	2	who assisted me in designing the methodology and data analysis	who assisted me in designing the methodology and data analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5563374	28868065	AJ	2	initiated research hypothesis and developed protocol	initiated research hypothesis and developed protocol	Conceived and designed the experiments	Conceptualization|Methodology	YES
5563374	28868065	All coauthors	2	provided input in the manuscript	provided input in the manuscript	-	-	NO
5563374	28868065	EB	2	initiated research hypothesis and developed protocol|conducted research, analyzed data, and written manuscript	initiated research hypothesis and developed protocol	Conceived and designed the experiments	Conceptualization|Methodology	YES
5563374	28868065	EB	2	initiated research hypothesis and developed protocol|conducted research, analyzed data, and written manuscript	conducted research, analyzed data, and written manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5563374	28868065	JL	2	provided inout in the protocol	provided inout in the protocol	Conceived and designed the experiments	Methodology	YES
5563374	28868065	PS	2	provided inout in the protocol	provided inout in the protocol	Conceived and designed the experiments	Methodology	YES
5563374	28868065	SK	2	provided inout in the protocol	provided inout in the protocol	Conceived and designed the experiments	Methodology	YES
5030209	27649908	All authors	PLoS52	screened abstracts and provided input to refine the study design|contributed to and approved the final manuscript	screened abstracts and provided input to refine the study design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5030209	27649908	All authors	PLoS52	screened abstracts and provided input to refine the study design|contributed to and approved the final manuscript	contributed to and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5030209	27649908	HW	PLoS52	designed the study|analyzed the data	designed the study	Conceived and designed the experiments	Methodology	YES
5030209	27649908	HW	PLoS52	designed the study|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5030209	27649908	JR	PLoS52	extracted the data, with support from all authors|wrote the first draft of the manuscript	extracted the data, with support from all authors	Performed the experiments	Investigation	YES
5030209	27649908	JR	PLoS52	extracted the data, with support from all authors|wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
5030209	27649908	JW	PLoS52	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5030209	27649908	NP	PLoS52	extracted the data, with support from all authors|wrote the first draft of the manuscript	extracted the data, with support from all authors	Performed the experiments	Investigation	YES
5030209	27649908	NP	PLoS52	extracted the data, with support from all authors|wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
5030209	27649908	RB	PLoS52	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5319064	28219344	BMS	2	prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5319064	28219344	CAS	2	prepared the grant application and developed the research programme that led to this work|prepared the manuscript	prepared the grant application and developed the research programme that led to this work	Performed the experiments	Investigation|Software	YES
5319064	28219344	CAS	2	prepared the grant application and developed the research programme that led to this work|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5319064	28219344	NAA	2	prepared the grant application and developed the research programme that led to this work	prepared the grant application and developed the research programme that led to this work	Performed the experiments	Investigation|Software	YES
5319064	28219344	ROA	2	carried out the sequencing and genotyping experiments, as well as analysis of sequence data|prepared the grant application and developed the research programme that led to this work|prepared the manuscript	carried out the sequencing and genotyping experiments, as well as analysis of sequence data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5319064	28219344	ROA	2	carried out the sequencing and genotyping experiments, as well as analysis of sequence data|prepared the grant application and developed the research programme that led to this work|prepared the manuscript	prepared the grant application and developed the research programme that led to this work	Performed the experiments	Investigation|Software	YES
5319064	28219344	ROA	2	carried out the sequencing and genotyping experiments, as well as analysis of sequence data|prepared the grant application and developed the research programme that led to this work|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5832649	29511537	All	1	Critical review and approval of manuscript	Critical review and approval of manuscript	Wrote the paper	Writing - Review & Editing	YES
5832649	29511537	DI	1	Study design|Data collection	Study design	Conceived and designed the experiments	Methodology	YES
5832649	29511537	DI	1	Study design|Data collection	Data collection	Performed the experiments	Investigation	YES
5832649	29511537	HT	1	Data collection	Data collection	Performed the experiments	Investigation	YES
5832649	29511537	JE	1	Study design	Study design	Conceived and designed the experiments	Methodology	YES
5832649	29511537	NC	1	Statistical analysis	Statistical analysis	Analyzed the data	Formal analysis	YES
5832649	29511537	NV	1	Study design|Data collection	Study design	Conceived and designed the experiments	Methodology	YES
5832649	29511537	NV	1	Study design|Data collection	Data collection	Performed the experiments	Investigation	YES
5832649	29511537	TA	1	Study design|Data collection|Writing first draft of manuscript	Study design	Conceived and designed the experiments	Methodology	YES
5832649	29511537	TA	1	Study design|Data collection|Writing first draft of manuscript	Data collection	Performed the experiments	Investigation	YES
5832649	29511537	TA	1	Study design|Data collection|Writing first draft of manuscript	Writing first draft of manuscript	Wrote the paper	Writing - Original Draft	YES
6306819	30356015	K.W.	CRediT	methodology	methodology	Performed the experiments	Methodology	YES
6306819	30356015	L.H.	CRediT	Conceptualization	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6306819	30356015	L.J.S.	CRediT	Conceptualization|methodology|Writing - original draft	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6306819	30356015	L.J.S.	CRediT	Conceptualization|methodology|Writing - original draft	methodology	Performed the experiments	Methodology	YES
6306819	30356015	L.J.S.	CRediT	Conceptualization|methodology|Writing - original draft	Writing - original draft	Wrote the paper	Writing - Original Draft	YES
6306819	30356015	M.C.W.	CRediT	Conceptualization	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6306819	30356015	R.M.C.	CRediT	Conceptualization	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
5319112	28219341	AK	2	developed the bambara groundnut dartseq analysis pipeline	developed the bambara groundnut dartseq analysis pipeline	-	-	NO
5319112	28219341	FM	2	developed the td population and helped to draft the manuscript	developed the td population and helped to draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5319112	28219341	HHC	2	carried out the genetic mapping and qtl analysis	carried out the genetic mapping and qtl analysis	Performed the experiments	Investigation	YES
5319112	28219341	JJ	2	developed the circos analysis	developed the circos analysis	-	-	NO
5319112	28219341	NSA	2	contributed phenotypic data and initial marker analysis in the td population	contributed phenotypic data and initial marker analysis in the td population	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5319112	28219341	PK	2	developed the ia population with marker information	developed the ia population with marker information	-	-	NO
5319112	28219341	SM	2	conceived of the study, and participated in its design and coordination and revised the manuscript	conceived of the study, and participated in its design and coordination and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Review & Editing	YES
5319112	28219341	WKH	2	carried out the cross species comparison analysis, participated in the genetic mapping and qtl analysis and drafted the manuscript	carried out the cross species comparison analysis, participated in the genetic mapping and qtl analysis and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4406554	25901733	CM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406554	25901733	CM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406554	25901733	CM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406554	25901733	CM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406554	25901733	DZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406554	25901733	DZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406554	25901733	DZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406554	25901733	JJvdL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406554	25901733	JJvdL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406554	25901733	JJvdL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406554	25901733	NMAvdM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406554	25901733	NMAvdM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406554	25901733	NMAvdM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406554	25901733	TW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406554	25901733	TW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406554	25901733	TW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406554	25901733	VPMGR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406554	25901733	VPMGR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406554	25901733	VPMGR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5563375	28868057	LL	2	designed experiments|analyzed and interpreted data|wrote the manuscript with contributions of all the authors	designed experiments	Conceived and designed the experiments	Methodology	YES
5563375	28868057	LL	2	designed experiments|analyzed and interpreted data|wrote the manuscript with contributions of all the authors	analyzed and interpreted data	Analyzed the data	Formal analysis	YES
5563375	28868057	LL	2	designed experiments|analyzed and interpreted data|wrote the manuscript with contributions of all the authors	wrote the manuscript with contributions of all the authors	Wrote the paper	Writing - Original Draft	YES
5563375	28868057	MH	2	analyzed and interpreted data	analyzed and interpreted data	Analyzed the data	Formal analysis	YES
5563375	28868057	MT	2	designed experiments|performed experiments|analyzed and interpreted data|wrote the manuscript with contributions of all the authors	designed experiments	Conceived and designed the experiments	Methodology	YES
5563375	28868057	MT	2	designed experiments|performed experiments|analyzed and interpreted data|wrote the manuscript with contributions of all the authors	performed experiments	Performed the experiments	Investigation	YES
5563375	28868057	MT	2	designed experiments|performed experiments|analyzed and interpreted data|wrote the manuscript with contributions of all the authors	analyzed and interpreted data	Analyzed the data	Formal analysis	YES
5563375	28868057	MT	2	designed experiments|performed experiments|analyzed and interpreted data|wrote the manuscript with contributions of all the authors	wrote the manuscript with contributions of all the authors	Wrote the paper	Writing - Original Draft	YES
5563375	28868057	SP	2	designed experiments|analyzed and interpreted data	designed experiments	Conceived and designed the experiments	Methodology	YES
5563375	28868057	SP	2	designed experiments|analyzed and interpreted data	analyzed and interpreted data	Analyzed the data	Formal analysis	YES
5563375	28868057	TT	2	analyzed and interpreted data	analyzed and interpreted data	Analyzed the data	Formal analysis	YES
6021149	30061768	Ahmadreza Yazdannik	2	contributed to the design and implementation of the research, to the analysis of the results and to the writing of the manuscript	contributed to the design and implementation of the research, to the analysis of the results and to the writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
6021149	30061768	Bahareh Khaky	2	contributed to the design and implementation of the research, to the analysis of the results and to the writing of the manuscript	contributed to the design and implementation of the research, to the analysis of the results and to the writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
6021149	30061768	Hosein Mahjoubipour	2	contributed to the design and implementation of the research, to the analysis of the results and to the writing of the manuscript	contributed to the design and implementation of the research, to the analysis of the results and to the writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5832650	29511535	All authors	2	contributed to this study	contributed to this study	-	-	NO
4406555	25901952	APF	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406555	25901952	CDS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406555	25901952	DAP	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406555	25901952	GDR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406555	25901952	GDR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406555	25901952	GDR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406555	25901952	GDR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406555	25901952	NNB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4406555	25901952	SGH	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406555	25901952	SJC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4406555	25901952	SJC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406555	25901952	SMW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4406555	25901952	TDC	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4406555	25901952	TDC	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4406555	25901952	TDC	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406555	25901952	WGW	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
6306828	30544807	H.B.	CRediT	writing--review and editing|supervision	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6306828	30544807	H.B.	CRediT	writing--review and editing|supervision	supervision	-	Supervision	YES
6306828	30544807	H.D.L.	CRediT	Conceptualization|methodology|writing--original draft preparation|writing--review and editing|supervision	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6306828	30544807	H.D.L.	CRediT	Conceptualization|methodology|writing--original draft preparation|writing--review and editing|supervision	methodology	Performed the experiments	Methodology	YES
6306828	30544807	H.D.L.	CRediT	Conceptualization|methodology|writing--original draft preparation|writing--review and editing|supervision	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6306828	30544807	H.D.L.	CRediT	Conceptualization|methodology|writing--original draft preparation|writing--review and editing|supervision	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6306828	30544807	H.D.L.	CRediT	Conceptualization|methodology|writing--original draft preparation|writing--review and editing|supervision	supervision	-	Supervision	YES
6306828	30544807	L.S.	CRediT	Conceptualization|methodology|data curation|writing--review and editing|visualization	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6306828	30544807	L.S.	CRediT	Conceptualization|methodology|data curation|writing--review and editing|visualization	methodology	Performed the experiments	Methodology	YES
6306828	30544807	L.S.	CRediT	Conceptualization|methodology|data curation|writing--review and editing|visualization	data curation	Analyzed the data	Data curation	YES
6306828	30544807	L.S.	CRediT	Conceptualization|methodology|data curation|writing--review and editing|visualization	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6306828	30544807	L.S.	CRediT	Conceptualization|methodology|data curation|writing--review and editing|visualization	visualization	Analyzed the data	Visualization	YES
6306828	30544807	M.R.	CRediT	writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6306828	30544807	S.D.B.	CRediT	writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6306828	30544807	W.M.	CRediT	Conceptualization|methodology|writing--review and editing|supervision	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6306828	30544807	W.M.	CRediT	Conceptualization|methodology|writing--review and editing|supervision	methodology	Performed the experiments	Methodology	YES
6306828	30544807	W.M.	CRediT	Conceptualization|methodology|writing--review and editing|supervision	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6306828	30544807	W.M.	CRediT	Conceptualization|methodology|writing--review and editing|supervision	supervision	-	Supervision	YES
5035769	27665722	DM	2	conceived of and designed the study and developed and analyzed the model|wrote the manuscript	conceived of and designed the study and developed and analyzed the model	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
5035769	27665722	DM	2	conceived of and designed the study and developed and analyzed the model|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5035769	27665722	DT	2	helped design the study and provided methodological and analytical inputs	helped design the study and provided methodological and analytical inputs	Conceived and designed the experiments|Performed the experiments	Methodology	YES
5035769	27665722	SM	2	reviewed the model|helped design the study and provided methodological and analytical inputs	reviewed the model	Performed the experiments	Methodology	YES
5035769	27665722	SM	2	reviewed the model|helped design the study and provided methodological and analytical inputs	helped design the study and provided methodological and analytical inputs	Conceived and designed the experiments|Performed the experiments	Methodology	YES
6021150	30061761	All authors	2	were included in all phases of the preparation of this article	were included in all phases of the preparation of this article	-	-	NO
5849781	29541450	AC	7	Responsible for islets processing and biochemical part of the methodology	Responsible for islets processing and biochemical part of the methodology	Performed the experiments	Investigation|Methodology	YES
5849781	29541450	AM	7	Participated in the study design and scientific review	Participated in the study design and scientific review	Conceived and designed the experiments	Methodology	YES
5849781	29541450	EC	7	Participated in the study design and scientific review	Participated in the study design and scientific review	Conceived and designed the experiments	Methodology	YES
5849781	29541450	FFE	7	Participated in the scientific review of the article and literature review	Participated in the scientific review of the article and literature review	Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5849781	29541450	FHFG	7	Participated in the study design and scientific review	Participated in the study design and scientific review	Conceived and designed the experiments	Methodology	YES
5849781	29541450	FYS	7	Participated in the scientific review of the article and literature review	Participated in the scientific review of the article and literature review	Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5849781	29541450	GHAM	7	Responsible for writing the main text. Participated in the study design and experiments and literature review	Responsible for writing the main text. Participated in the study design and experiments and literature review	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Review & Editing	YES
5849781	29541450	LACD	7	Participated in the study design and scientific review	Participated in the study design and scientific review	Conceived and designed the experiments	Methodology	YES
5849781	29541450	LRI	7	Responsible for writing the main text. Participated in the study design and experiments and literature review	Responsible for writing the main text. Participated in the study design and experiments and literature review	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Review & Editing	YES
5849781	29541450	LTO	7	Participated in the scientific review of the article and literature review	Participated in the scientific review of the article and literature review	Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5849781	29541450	VRS	7	Participated in the study design and scientific review	Participated in the study design and scientific review	Conceived and designed the experiments	Methodology	YES
5849781	29541450	WA	7	Participated in the study design and scientific review	Participated in the study design and scientific review	Conceived and designed the experiments	Methodology	YES
5849781	29541450	YJJ	7	Responsible for writing the main text. Participated in the study design and experiments and literature review	Responsible for writing the main text. Participated in the study design and experiments and literature review	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Review & Editing	YES
4123610	25132995	Donald G. Brunder	2	had overall responsibility for the conception of bioinformatics infrastructure for retrieving and archiving radiologic imaging data, designed and developed software for bd analyses, and was involved in data interpretation and approval of the version to be published	had overall responsibility for the conception of bioinformatics infrastructure for retrieving and archiving radiologic imaging data, designed and developed software for bd analyses, and was involved in data interpretation and approval of the version to be published	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Software|Visualization	YES
4123610	25132995	Fatima Nayeem	2	contributed to study management, including sample and data acquisition, quality-control, laboratory analyses, statistical analyses, interpretation of the data, preparation of the paper, and approval of the version to be published	contributed to study management, including sample and data acquisition, quality-control, laboratory analyses, statistical analyses, interpretation of the data, preparation of the paper, and approval of the version to be published	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Formal analysis|Investigation|Resources	YES
4123610	25132995	Hyunsu Ju	2	had overall responsibility for design and conduct of statistical model analyses and interpretation of the data, contributed to manuscript preparation, and approved the version to be published	had overall responsibility for design and conduct of statistical model analyses and interpretation of the data, contributed to manuscript preparation, and approved the version to be published	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4123610	25132995	Jane W. Lu	2	had overall responsibility for the conception, design, and management of the study and acquisition, analyses, and interpretation of the data for presentation and publications and has given final approval of the version to be published	had overall responsibility for the conception, design, and management of the study and acquisition, analyses, and interpretation of the data for presentation and publications and has given final approval of the version to be published	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Data curation|Formal analysis|Investigation|Methodology|Project administration	YES
4123610	25132995	Karl E. Anderson	2	had overall responsibility for conception and design of the clinical aspect of the study, interpreted clinical data and outcomes of interest, and has contributed to and approved the version to be published	had overall responsibility for conception and design of the clinical aspect of the study, interpreted clinical data and outcomes of interest, and has contributed to and approved the version to be published	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
4123610	25132995	Katrina Jencks	2	performed many of the histogram segmentation analyses	performed many of the histogram segmentation analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4123610	25132995	Manubai Nagamani	2	had overall responsibility for conception, design, acquisition, and interpretation of the reproductive endocrine aspect of clinical and research data and has participated in and approved the version to be published	had overall responsibility for conception, design, acquisition, and interpretation of the reproductive endocrine aspect of clinical and research data and has participated in and approved the version to be published	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation|Methodology	YES
4123610	25132995	Mouyong Liu	2	developed the research database	developed the research database	Contributed reagents/materials/analysis tools	Software	YES
4123610	25132995	Rett Hutto	2	performed the density analyses and was instrumental in finalizing the bd analysis protocol	performed the density analyses and was instrumental in finalizing the bd analysis protocol	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
4123610	25132995	Thomas Nishino	2	developed the mri image analysis methods	developed the mri image analysis methods	Performed the experiments|Analyzed the data	Methodology|Visualization	YES
4123610	25132995	Tuenchit Khamapirad	2	had overall responsibility for conception, design, acquisition, and interpretation of mammography and magnetic resonance images of the breast, and design of bd analyses and has approved the version to be published	had overall responsibility for conception, design, acquisition, and interpretation of mammography and magnetic resonance images of the breast, and design of bd analyses and has approved the version to be published	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation|Visualization	YES
4123610	25132995	Xin Ma	2	performed serum hormone assays	performed serum hormone assays	Performed the experiments	Investigation	YES
5563376	28868061	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5563376	28868061	HL	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5563376	28868061	LC	2	extracted rna and performed the qrt-pcr experiments|designed the vectors for subcellular localization	extracted rna and performed the qrt-pcr experiments	Performed the experiments	Investigation	YES
5563376	28868061	LC	2	extracted rna and performed the qrt-pcr experiments|designed the vectors for subcellular localization	designed the vectors for subcellular localization	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5563376	28868061	LQ	2	conceived the study, analyzed the data, and drafted the manuscript|cultivated the soybean materials and collected the soybean samples	conceived the study, analyzed the data, and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
5563376	28868061	LQ	2	conceived the study, analyzed the data, and drafted the manuscript|cultivated the soybean materials and collected the soybean samples	cultivated the soybean materials and collected the soybean samples	Performed the experiments	Investigation	YES
5563376	28868061	LX	2	cultivated the soybean materials and collected the soybean samples	cultivated the soybean materials and collected the soybean samples	Performed the experiments	Investigation	YES
5563376	28868061	PH	2	extracted rna and performed the qrt-pcr experiments	extracted rna and performed the qrt-pcr experiments	Performed the experiments	Investigation	YES
5563376	28868061	TW	2	conducted the statistical analyses of raw data|revised the manuscript	conducted the statistical analyses of raw data	Analyzed the data	Formal analysis	YES
5563376	28868061	TW	2	conducted the statistical analyses of raw data|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5563376	28868061	XH	2	cultivated the soybean materials and collected the soybean samples	cultivated the soybean materials and collected the soybean samples	Performed the experiments	Investigation	YES
5563376	28868061	XL	2	conceived the study, analyzed the data, and drafted the manuscript	conceived the study, analyzed the data, and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
5563376	28868061	YL	2	extracted rna and performed the qrt-pcr experiments	extracted rna and performed the qrt-pcr experiments	Performed the experiments	Investigation	YES
4406557	25901369	CA	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4406557	25901369	CG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406557	25901369	CG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4406557	25901369	CG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406557	25901369	CJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406557	25901369	CJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406557	25901369	CJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406557	25901369	CJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406557	25901369	CJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406557	25901369	DS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406557	25901369	DS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4406557	25901369	DS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406557	25901369	HB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4406557	25901369	HB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406557	25901369	JPC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406557	25901369	JPC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406557	25901369	JPC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406557	25901369	NG	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4406557	25901369	NG	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4406557	25901369	PH	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406557	25901369	PP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4406557	25901369	PP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406557	25901369	SM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4406557	25901369	WV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406557	25901369	WV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4406557	25901369	WV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
6306834	30562992	A.J.C.	CRediT	Writing-review & editing	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6306834	30562992	D.L.	CRediT	Conceptualization|Methodology|Validation|Resources|Writing-review & editing|Supervision	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6306834	30562992	D.L.	CRediT	Conceptualization|Methodology|Validation|Resources|Writing-review & editing|Supervision	Methodology	Performed the experiments	Methodology	YES
6306834	30562992	D.L.	CRediT	Conceptualization|Methodology|Validation|Resources|Writing-review & editing|Supervision	Validation	Performed the experiments	Validation	YES
6306834	30562992	D.L.	CRediT	Conceptualization|Methodology|Validation|Resources|Writing-review & editing|Supervision	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6306834	30562992	D.L.	CRediT	Conceptualization|Methodology|Validation|Resources|Writing-review & editing|Supervision	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6306834	30562992	D.L.	CRediT	Conceptualization|Methodology|Validation|Resources|Writing-review & editing|Supervision	Supervision	-	Supervision	YES
6306834	30562992	E.Z.	CRediT	Writing-review & editing	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6306834	30562992	J.I.	CRediT	Writing-review & editing	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6306834	30562992	R.O.-A.	CRediT	Conceptualization|Methodology|Validation|Formal analysis|Investigation|Writing-original draft preparation|Visualization|Project administration	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6306834	30562992	R.O.-A.	CRediT	Conceptualization|Methodology|Validation|Formal analysis|Investigation|Writing-original draft preparation|Visualization|Project administration	Methodology	Performed the experiments	Methodology	YES
6306834	30562992	R.O.-A.	CRediT	Conceptualization|Methodology|Validation|Formal analysis|Investigation|Writing-original draft preparation|Visualization|Project administration	Validation	Performed the experiments	Validation	YES
6306834	30562992	R.O.-A.	CRediT	Conceptualization|Methodology|Validation|Formal analysis|Investigation|Writing-original draft preparation|Visualization|Project administration	Formal analysis	Analyzed the data	Formal analysis	YES
6306834	30562992	R.O.-A.	CRediT	Conceptualization|Methodology|Validation|Formal analysis|Investigation|Writing-original draft preparation|Visualization|Project administration	Investigation	Performed the experiments	Investigation	YES
6306834	30562992	R.O.-A.	CRediT	Conceptualization|Methodology|Validation|Formal analysis|Investigation|Writing-original draft preparation|Visualization|Project administration	Writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
6306834	30562992	R.O.-A.	CRediT	Conceptualization|Methodology|Validation|Formal analysis|Investigation|Writing-original draft preparation|Visualization|Project administration	Visualization	Analyzed the data	Visualization	YES
6306834	30562992	R.O.-A.	CRediT	Conceptualization|Methodology|Validation|Formal analysis|Investigation|Writing-original draft preparation|Visualization|Project administration	Project administration	-	Project administration	YES
6306834	30562992	S.Z.	CRediT	Writing-review & editing	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
5852262	29552341	AN	1	Drafting the work or revising it critically for important intellectual content	Drafting the work or revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5852262	29552341	CA	1	Acquisition, analysis, or interpretation of data for the work	Acquisition, analysis, or interpretation of data for the work	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5852262	29552341	GB	1	Acquisition, analysis, or interpretation of data for the work	Acquisition, analysis, or interpretation of data for the work	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5852262	29552341	LT	1	Conception or design of work|Acquisition, analysis, or interpretation of data for the work|Drafting the work or revising it critically for important intellectual content|Final approval of the version to be published	Conception or design of work	Conceived and designed the experiments	Conceptualization	YES
5852262	29552341	LT	1	Conception or design of work|Acquisition, analysis, or interpretation of data for the work|Drafting the work or revising it critically for important intellectual content|Final approval of the version to be published	Acquisition, analysis, or interpretation of data for the work	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5852262	29552341	LT	1	Conception or design of work|Acquisition, analysis, or interpretation of data for the work|Drafting the work or revising it critically for important intellectual content|Final approval of the version to be published	Drafting the work or revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5852262	29552341	LT	1	Conception or design of work|Acquisition, analysis, or interpretation of data for the work|Drafting the work or revising it critically for important intellectual content|Final approval of the version to be published	Final approval of the version to be published	-	-	NO
5852262	29552341	RF	1	Acquisition, analysis, or interpretation of data for the work	Acquisition, analysis, or interpretation of data for the work	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5852262	29552341	SB	1	Acquisition, analysis, or interpretation of data for the work	Acquisition, analysis, or interpretation of data for the work	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6021151	30061770	Masoud Sadeghi	1	Conception, design, acquisition of data, and analysis and interpretation of data|Drafting the article	Conception, design, acquisition of data, and analysis and interpretation of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation	YES
6021151	30061770	Masoud Sadeghi	1	Conception, design, acquisition of data, and analysis and interpretation of data|Drafting the article	Drafting the article	Wrote the paper	Writing - Original Draft	YES
6021151	30061770	Reza Fattahian	1	Conception, design, acquisition of data, and analysis and interpretation of data	Conception, design, acquisition of data, and analysis and interpretation of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation	YES
6021151	30061770	Seyed Reza Bagheri	1	Critically revising the article	Critically revising the article	Wrote the paper	Writing - Review & Editing	YES
5039239	27677395	All authors	2	interpreted the data, revised the manuscript and reviewed the final paper	interpreted the data, revised the manuscript and reviewed the final paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5039239	27677395	CRH	2	conceived the study|provided technical input	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5039239	27677395	CRH	2	conceived the study|provided technical input	provided technical input	-	-	NO
5039239	27677395	IS	2	coordinated data collection and implementation at clinic sites	coordinated data collection and implementation at clinic sites	Performed the experiments	Investigation|Project administration	YES
5039239	27677395	JB	2	coordinated data collection and implementation at clinic sites	coordinated data collection and implementation at clinic sites	Performed the experiments	Investigation|Project administration	YES
5039239	27677395	JR	2	conceived the study|designed the statistical analyses|did the statistical analysis and drafted the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5039239	27677395	JR	2	conceived the study|designed the statistical analyses|did the statistical analysis and drafted the manuscript	designed the statistical analyses	Conceived and designed the experiments|Analyzed the data	Formal analysis	YES
5039239	27677395	JR	2	conceived the study|designed the statistical analyses|did the statistical analysis and drafted the manuscript	did the statistical analysis and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5039239	27677395	KS	2	coordinated data collection and implementation at clinic sites	coordinated data collection and implementation at clinic sites	Performed the experiments	Investigation|Project administration	YES
5039239	27677395	LL	2	coordinated data collection and implementation at clinic sites|provided technical input	coordinated data collection and implementation at clinic sites	Performed the experiments	Investigation|Project administration	YES
5039239	27677395	LL	2	coordinated data collection and implementation at clinic sites|provided technical input	provided technical input	-	-	NO
5039239	27677395	MF	2	conceived the study|designed the statistical analyses	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5039239	27677395	MF	2	conceived the study|designed the statistical analyses	designed the statistical analyses	Conceived and designed the experiments|Analyzed the data	Formal analysis	YES
5039239	27677395	MM	2	coordinated data collection and implementation at clinic sites|provided technical input	coordinated data collection and implementation at clinic sites	Performed the experiments	Investigation|Project administration	YES
5039239	27677395	MM	2	coordinated data collection and implementation at clinic sites|provided technical input	provided technical input	-	-	NO
5039239	27677395	OE	2	coordinated data collection and implementation at clinic sites	coordinated data collection and implementation at clinic sites	Performed the experiments	Investigation|Project administration	YES
5039239	27677395	PI	2	conceived the study|provided technical input	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5039239	27677395	PI	2	conceived the study|provided technical input	provided technical input	-	-	NO
5039239	27677395	RB	2	provided technical input	provided technical input	-	-	NO
5319170	28219347	All authors	2	were involved in subsequent rounds of revisions, and read and approved the final manuscript	were involved in subsequent rounds of revisions, and read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5319170	28219347	BR	2	wrote the first draft and contributed to initial revisions	wrote the first draft and contributed to initial revisions	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5319170	28219347	CR	2	wrote the first draft and contributed to initial revisions	wrote the first draft and contributed to initial revisions	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5319170	28219347	DP	2	wrote the first draft and contributed to initial revisions	wrote the first draft and contributed to initial revisions	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5319170	28219347	MG-C	2	wrote the first draft and contributed to initial revisions	wrote the first draft and contributed to initial revisions	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5319170	28219347	MS	2	wrote the first draft and contributed to initial revisions	wrote the first draft and contributed to initial revisions	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5319170	28219347	SR	2	wrote the first draft and contributed to initial revisions	wrote the first draft and contributed to initial revisions	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5319170	28219347	TK	2	wrote the first draft and contributed to initial revisions	wrote the first draft and contributed to initial revisions	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5319170	28219347	XG	2	wrote the first draft and contributed to initial revisions	wrote the first draft and contributed to initial revisions	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5319170	28219347	YP	2	wrote the first draft and contributed to initial revisions	wrote the first draft and contributed to initial revisions	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5319170	28219347	ZL	2	is the organizer of the workshop and provided the very initial draft	is the organizer of the workshop and provided the very initial draft	Wrote the paper	Writing - Original Draft	YES
5563380	28868064	DH	1	Acquisition of data for the study	Acquisition of data for the study	Performed the experiments	Investigation	YES
5563380	28868064	DX	1	Acquisition of data for the study	Acquisition of data for the study	Performed the experiments	Investigation	YES
5563380	28868064	DZ	1	Conception and design of the study|Acquisition of data for the study|Analysis of data for the work|Interpretation of data for the work	Conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5563380	28868064	DZ	1	Conception and design of the study|Acquisition of data for the study|Analysis of data for the work|Interpretation of data for the work	Acquisition of data for the study	Performed the experiments	Investigation	YES
5563380	28868064	DZ	1	Conception and design of the study|Acquisition of data for the study|Analysis of data for the work|Interpretation of data for the work	Analysis of data for the work	Analyzed the data	Formal analysis	YES
5563380	28868064	DZ	1	Conception and design of the study|Acquisition of data for the study|Analysis of data for the work|Interpretation of data for the work	Interpretation of data for the work	Analyzed the data	Formal analysis	YES
5563380	28868064	LH	1	Conception and design of the study|Analysis of data for the work|Interpretation of data for the work	Conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5563380	28868064	LH	1	Conception and design of the study|Analysis of data for the work|Interpretation of data for the work	Analysis of data for the work	Analyzed the data	Formal analysis	YES
5563380	28868064	LH	1	Conception and design of the study|Analysis of data for the work|Interpretation of data for the work	Interpretation of data for the work	Analyzed the data	Formal analysis	YES
5563380	28868064	QG	1	Acquisition of data for the study	Acquisition of data for the study	Performed the experiments	Investigation	YES
5563380	28868064	WC	1	Conception and design of the study|Acquisition of data for the study|Analysis of data for the work|Interpretation of data for the work	Conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5563380	28868064	WC	1	Conception and design of the study|Acquisition of data for the study|Analysis of data for the work|Interpretation of data for the work	Acquisition of data for the study	Performed the experiments	Investigation	YES
5563380	28868064	WC	1	Conception and design of the study|Acquisition of data for the study|Analysis of data for the work|Interpretation of data for the work	Analysis of data for the work	Analyzed the data	Formal analysis	YES
5563380	28868064	WC	1	Conception and design of the study|Acquisition of data for the study|Analysis of data for the work|Interpretation of data for the work	Interpretation of data for the work	Analyzed the data	Formal analysis	YES
5563380	28868064	WeiS	1	Acquisition of data for the study|Interpretation of data for the work	Acquisition of data for the study	Performed the experiments	Investigation	YES
5563380	28868064	WeiS	1	Acquisition of data for the study|Interpretation of data for the work	Interpretation of data for the work	Analyzed the data	Formal analysis	YES
5563380	28868064	WenS	1	Acquisition of data for the study|Interpretation of data for the work	Acquisition of data for the study	Performed the experiments	Investigation	YES
5563380	28868064	WenS	1	Acquisition of data for the study|Interpretation of data for the work	Interpretation of data for the work	Analyzed the data	Formal analysis	YES
5563380	28868064	YM	1	Acquisition of data for the study	Acquisition of data for the study	Performed the experiments	Investigation	YES
5563380	28868064	YR	1	Acquisition of data for the study	Acquisition of data for the study	Performed the experiments	Investigation	YES
5563380	28868064	YS	1	Acquisition of data for the study	Acquisition of data for the study	Performed the experiments	Investigation	YES
6021152	30061775	All authors	2	contributed equally in design, literature search, discussion, first draft	contributed equally in design, literature search, discussion, first draft	Conceived and designed the experiments|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4406558	25902316	GA	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406558	25902316	GA	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406558	25902316	GSR	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406558	25902316	GSR	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406558	25902316	GSR	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406558	25902316	GSR	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406558	25902316	MM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406558	25902316	MM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4406558	25902316	MM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406558	25902316	MS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406558	25902316	MS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406558	25902316	MS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406558	25902316	MS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406558	25902316	RS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406558	25902316	RS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406558	25902316	RS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5852268	29552340	Andrea Mazzella	2	collected and analysed the data|edited the manuscript	collected and analysed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5852268	29552340	Andrea Mazzella	2	collected and analysed the data|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5852268	29552340	Edward Sharples	2	designed the study|edited the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5852268	29552340	Edward Sharples	2	designed the study|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5852268	29552340	Michael Reschen	2	designed the study|collected and analysed the data|wrote the manuscript|edited the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5852268	29552340	Michael Reschen	2	designed the study|collected and analysed the data|wrote the manuscript|edited the manuscript	collected and analysed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5852268	29552340	Michael Reschen	2	designed the study|collected and analysed the data|wrote the manuscript|edited the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5852268	29552340	Michael Reschen	2	designed the study|collected and analysed the data|wrote the manuscript|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
4502275	26229967	N. Aymami	2	shared first authorship	shared first authorship	-	-	NO
4502275	26229967	S. Jimenez-Murcia	2	shared first authorship	shared first authorship	-	-	NO
6306838	30486520	A.S.	CRediT	Conceptualization|methodology|investigation|writing--review and editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6306838	30486520	A.S.	CRediT	Conceptualization|methodology|investigation|writing--review and editing	methodology	Performed the experiments	Methodology	YES
6306838	30486520	A.S.	CRediT	Conceptualization|methodology|investigation|writing--review and editing	investigation	Performed the experiments	Investigation	YES
6306838	30486520	A.S.	CRediT	Conceptualization|methodology|investigation|writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6306838	30486520	D.F.	CRediT	software|resources|writing--review and editing	software	Contributed reagents/materials/analysis tools	Software	YES
6306838	30486520	D.F.	CRediT	software|resources|writing--review and editing	resources	Contributed reagents/materials/analysis tools	Resources	YES
6306838	30486520	D.F.	CRediT	software|resources|writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6306838	30486520	J.C.	CRediT	Conceptualization|methodology|validation|investigation|data curation|writing--original draft preparation|writing--review and editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6306838	30486520	J.C.	CRediT	Conceptualization|methodology|validation|investigation|data curation|writing--original draft preparation|writing--review and editing	methodology	Performed the experiments	Methodology	YES
6306838	30486520	J.C.	CRediT	Conceptualization|methodology|validation|investigation|data curation|writing--original draft preparation|writing--review and editing	validation	Performed the experiments	Validation	YES
6306838	30486520	J.C.	CRediT	Conceptualization|methodology|validation|investigation|data curation|writing--original draft preparation|writing--review and editing	investigation	Performed the experiments	Investigation	YES
6306838	30486520	J.C.	CRediT	Conceptualization|methodology|validation|investigation|data curation|writing--original draft preparation|writing--review and editing	data curation	Analyzed the data	Data curation	YES
6306838	30486520	J.C.	CRediT	Conceptualization|methodology|validation|investigation|data curation|writing--original draft preparation|writing--review and editing	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6306838	30486520	J.C.	CRediT	Conceptualization|methodology|validation|investigation|data curation|writing--original draft preparation|writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6306838	30486520	J.L.	CRediT	software|validation|formal analysis|resources|data curation|writing--review and editing	software	Contributed reagents/materials/analysis tools	Software	YES
6306838	30486520	J.L.	CRediT	software|validation|formal analysis|resources|data curation|writing--review and editing	validation	Performed the experiments	Validation	YES
6306838	30486520	J.L.	CRediT	software|validation|formal analysis|resources|data curation|writing--review and editing	formal analysis	Analyzed the data	Formal analysis	YES
6306838	30486520	J.L.	CRediT	software|validation|formal analysis|resources|data curation|writing--review and editing	resources	Contributed reagents/materials/analysis tools	Resources	YES
6306838	30486520	J.L.	CRediT	software|validation|formal analysis|resources|data curation|writing--review and editing	data curation	Analyzed the data	Data curation	YES
6306838	30486520	J.L.	CRediT	software|validation|formal analysis|resources|data curation|writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6306838	30486520	L.K.	CRediT	Conceptualization|methodology|software|validation|resources|writing--review and editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6306838	30486520	L.K.	CRediT	Conceptualization|methodology|software|validation|resources|writing--review and editing	methodology	Performed the experiments	Methodology	YES
6306838	30486520	L.K.	CRediT	Conceptualization|methodology|software|validation|resources|writing--review and editing	software	Contributed reagents/materials/analysis tools	Software	YES
6306838	30486520	L.K.	CRediT	Conceptualization|methodology|software|validation|resources|writing--review and editing	validation	Performed the experiments	Validation	YES
6306838	30486520	L.K.	CRediT	Conceptualization|methodology|software|validation|resources|writing--review and editing	resources	Contributed reagents/materials/analysis tools	Resources	YES
6306838	30486520	L.K.	CRediT	Conceptualization|methodology|software|validation|resources|writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6021153	30061763	All authors	2	were included in all phases of the preparation of this article	were included in all phases of the preparation of this article	-	-	NO
5319172	28219339	ADZ	2	contributed to bioinformatics analysis and wrote the manuscript	contributed to bioinformatics analysis and wrote the manuscript	Wrote the paper	Formal analysis|Writing - Original Draft	YES
5319172	28219339	LBH	2	contributed to bioinformatics analysis and wrote the manuscript|participated in primer design and rt-qpcr analysis	contributed to bioinformatics analysis and wrote the manuscript	Wrote the paper	Formal analysis|Writing - Original Draft	YES
5319172	28219339	LBH	2	contributed to bioinformatics analysis and wrote the manuscript|participated in primer design and rt-qpcr analysis	participated in primer design and rt-qpcr analysis	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5319172	28219339	LJL	2	performed sample collection and rna isolation	performed sample collection and rna isolation	Performed the experiments	Investigation	YES
5319172	28219339	PFC	2	participated in primer design and rt-qpcr analysis	participated in primer design and rt-qpcr analysis	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5319172	28219339	RH	2	performed sample collection and rna isolation	performed sample collection and rna isolation	Performed the experiments	Investigation	YES
5319172	28219339	YML	2	performed sample collection and rna isolation	performed sample collection and rna isolation	Performed the experiments	Investigation	YES
5319172	28219339	YPW	2	contributed to the design of the research and manuscript editing	contributed to the design of the research and manuscript editing	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5319172	28219339	ZYZ	2	contributed to the design of the research and manuscript editing	contributed to the design of the research and manuscript editing	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5904764	29904609	FG	2	was the lead author and led study design, conducted data collection and analysis, conducted the literature review, and formulated and coordinated the article for publication	was the lead author and led study design, conducted data collection and analysis, conducted the literature review, and formulated and coordinated the article for publication	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Project administration|Writing - Review & Editing	YES
5904764	29904609	FGs	2	primary supervisor during this study, and assisted in drafting and editing, design, and data collection and analysis	primary supervisor during this study, and assisted in drafting and editing, design, and data collection and analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
5904764	29904609	JC	2	contributed to the study design, data collection and analysis, and paper drafting and editing	contributed to the study design, data collection and analysis, and paper drafting and editing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5904764	29904609	LW	2	contributed to the study design, helped in providing clinical support during patient data collection and analysis, and assisted in paper drafting and editing	contributed to the study design, helped in providing clinical support during patient data collection and analysis, and assisted in paper drafting and editing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5904764	29904609	PTB	2	contributed to the study design, data collection and analysis, and paper drafting and editing	contributed to the study design, data collection and analysis, and paper drafting and editing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5563381	28868063	All authors	PLoS52	participated in editing the manuscript and approved its final version	participated in editing the manuscript and approved its final version	Wrote the paper	Writing - Review & Editing	YES
5563381	28868063	BB	PLoS52	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5563381	28868063	LN	PLoS52	conceived and designed the work|performed the experiments and analyzed the data|wrote the paper	conceived and designed the work	Conceived and designed the experiments	Conceptualization	YES
5563381	28868063	LN	PLoS52	conceived and designed the work|performed the experiments and analyzed the data|wrote the paper	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5563381	28868063	LN	PLoS52	conceived and designed the work|performed the experiments and analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5563381	28868063	NLR	PLoS52	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5563381	28868063	RM	PLoS52	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5563381	28868063	SS	PLoS52	performed the experiments and analyzed the data|wrote the paper	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5563381	28868063	SS	PLoS52	performed the experiments and analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5043092	27687145	ATM	2	as a science facilitator, oversaw study operations across the sites and managed the project	as a science facilitator, oversaw study operations across the sites and managed the project	Performed the experiments	Investigation|Project administration|Supervision	YES
5043092	27687145	BW	2	who, together, conducted the statistical analyses and drafted the statistical sections of the paper	who, together, conducted the statistical analyses and drafted the statistical sections of the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5043092	27687145	C. All	2	authors read, approved and contributed to editing of the final manuscript	authors read, approved and contributed to editing of the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5043092	27687145	DC	2	were protocol co-investigators and largely conceptualized the study	were protocol co-investigators and largely conceptualized the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5043092	27687145	JFM	2	assisted with the with	assisted with the with	-	-	NO
5043092	27687145	JPH	2	assisted with the with|oversaw the data management	assisted with the with	-	-	NO
5043092	27687145	JPH	2	assisted with the with|oversaw the data management	oversaw the data management	Analyzed the data	Data curation|Supervision	YES
5043092	27687145	KS	2	were the site investigators and contributed to the cultural aspects and logistical procedures of the study at their respective sites	were the site investigators and contributed to the cultural aspects and logistical procedures of the study at their respective sites	Performed the experiments	Investigation	YES
5043092	27687145	MJM	2	were protocol co-investigators and largely conceptualized the study	were protocol co-investigators and largely conceptualized the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5043092	27687145	ML	2	were the site investigators and contributed to the cultural aspects and logistical procedures of the study at their respective sites	were the site investigators and contributed to the cultural aspects and logistical procedures of the study at their respective sites	Performed the experiments	Investigation	YES
5043092	27687145	RKF	2	were the site investigators and contributed to the cultural aspects and logistical procedures of the study at their respective sites	were the site investigators and contributed to the cultural aspects and logistical procedures of the study at their respective sites	Performed the experiments	Investigation	YES
5043092	27687145	SAS	2	overall, wrote the first draft of the manuscript, with	overall, wrote the first draft of the manuscript, with	Wrote the paper	Writing - Original Draft	YES
5043092	27687145	VE	2	gave input to design throughout the study development and implementation	gave input to design throughout the study development and implementation	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6021154	30061772	All authors	2	gave substantial contribution to the conception or design of article|revised it critically and gave final approval of the version to be published	gave substantial contribution to the conception or design of article	Conceived and designed the experiments	Conceptualization	YES
6021154	30061772	All authors	2	gave substantial contribution to the conception or design of article|revised it critically and gave final approval of the version to be published	revised it critically and gave final approval of the version to be published	Wrote the paper	Writing - Review & Editing	YES
6306848	30261681	E.Y.H.Y.	CRediT	Conceptualization|Software|Writing-original draft preparation|Visualization|Supervision	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6306848	30261681	E.Y.H.Y.	CRediT	Conceptualization|Software|Writing-original draft preparation|Visualization|Supervision	Software	Contributed reagents/materials/analysis tools	Software	YES
6306848	30261681	E.Y.H.Y.	CRediT	Conceptualization|Software|Writing-original draft preparation|Visualization|Supervision	Writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
6306848	30261681	E.Y.H.Y.	CRediT	Conceptualization|Software|Writing-original draft preparation|Visualization|Supervision	Visualization	Analyzed the data	Visualization	YES
6306848	30261681	E.Y.H.Y.	CRediT	Conceptualization|Software|Writing-original draft preparation|Visualization|Supervision	Supervision	-	Supervision	YES
6306848	30261681	R.S.D.M.	CRediT	Conceptualization|Methodology|Validation|Formal analysis|Investigation|Resources|Data curation|Writing-original draft preparation|Writing-review & editing|Project administration	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6306848	30261681	R.S.D.M.	CRediT	Conceptualization|Methodology|Validation|Formal analysis|Investigation|Resources|Data curation|Writing-original draft preparation|Writing-review & editing|Project administration	Methodology	Performed the experiments	Methodology	YES
6306848	30261681	R.S.D.M.	CRediT	Conceptualization|Methodology|Validation|Formal analysis|Investigation|Resources|Data curation|Writing-original draft preparation|Writing-review & editing|Project administration	Validation	Performed the experiments	Validation	YES
6306848	30261681	R.S.D.M.	CRediT	Conceptualization|Methodology|Validation|Formal analysis|Investigation|Resources|Data curation|Writing-original draft preparation|Writing-review & editing|Project administration	Formal analysis	Analyzed the data	Formal analysis	YES
6306848	30261681	R.S.D.M.	CRediT	Conceptualization|Methodology|Validation|Formal analysis|Investigation|Resources|Data curation|Writing-original draft preparation|Writing-review & editing|Project administration	Investigation	Performed the experiments	Investigation	YES
6306848	30261681	R.S.D.M.	CRediT	Conceptualization|Methodology|Validation|Formal analysis|Investigation|Resources|Data curation|Writing-original draft preparation|Writing-review & editing|Project administration	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6306848	30261681	R.S.D.M.	CRediT	Conceptualization|Methodology|Validation|Formal analysis|Investigation|Resources|Data curation|Writing-original draft preparation|Writing-review & editing|Project administration	Data curation	Analyzed the data	Data curation	YES
6306848	30261681	R.S.D.M.	CRediT	Conceptualization|Methodology|Validation|Formal analysis|Investigation|Resources|Data curation|Writing-original draft preparation|Writing-review & editing|Project administration	Writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
6306848	30261681	R.S.D.M.	CRediT	Conceptualization|Methodology|Validation|Formal analysis|Investigation|Resources|Data curation|Writing-original draft preparation|Writing-review & editing|Project administration	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6306848	30261681	R.S.D.M.	CRediT	Conceptualization|Methodology|Validation|Formal analysis|Investigation|Resources|Data curation|Writing-original draft preparation|Writing-review & editing|Project administration	Project administration	-	Project administration	YES
4502276	26229959	Holger Jahr	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
4502276	26229959	Sven Nebelung	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
4406561	25902288	BRM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406561	25902288	CEN	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406561	25902288	CMG	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406561	25902288	DBL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406561	25902288	JAB	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406561	25902288	JC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406561	25902288	JC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406561	25902288	JC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406561	25902288	JC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406561	25902288	JC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406561	25902288	JCW	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406561	25902288	JH	PLoS5	Web service construction	Web service construction	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
4406561	25902288	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Web service construction	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406561	25902288	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Web service construction	Performed the experiments	Performed the experiments	Investigation	YES
4406561	25902288	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Web service construction	Analyzed the data	Analyzed the data	Formal analysis	YES
4406561	25902288	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Web service construction	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406561	25902288	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Web service construction	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406561	25902288	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Web service construction	Web service construction	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
4406561	25902288	JMW	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406561	25902288	LS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406561	25902288	MH	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406561	25902288	TPM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406561	25902288	VVM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406561	25902288	WRF	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406561	25902288	YL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4160608	25328711	All authors	2	have agreed to be accountable for all aspects of the work and all have approved the final version of the paper to be published	have agreed to be accountable for all aspects of the work and all have approved the final version of the paper to be published	-	-	NO
4160608	25328711	Ida Hageman	2	planned the study, designed the study, interpreted the data, and revised the paper	planned the study, designed the study, interpreted the data, and revised the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Review & Editing	YES
4160608	25328711	Ismail Gogenur	2	had full access to all the data in the study, take responsibility for the integrity of the data and the accuracy of the data analysis, and had final responsibility for the decision to submit for publication|planned the study, designed the study, initiated the study, interpreted the data and revised the paper	had full access to all the data in the study, take responsibility for the integrity of the data and the accuracy of the data analysis, and had final responsibility for the decision to submit for publication	Analyzed the data	Data curation|Formal analysis	YES
4160608	25328711	Ismail Gogenur	2	had full access to all the data in the study, take responsibility for the integrity of the data and the accuracy of the data analysis, and had final responsibility for the decision to submit for publication|planned the study, designed the study, initiated the study, interpreted the data and revised the paper	planned the study, designed the study, initiated the study, interpreted the data and revised the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Review & Editing	YES
4160608	25328711	Jacob Rosenberg	2	planned the study, designed the study, initiated the study, interpreted the data and revised the paper	planned the study, designed the study, initiated the study, interpreted the data and revised the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Review & Editing	YES
4160608	25328711	Laerke Toftegard Andersen	2	collected the data and revised the paper	collected the data and revised the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4160608	25328711	Lars Simon Rasmussen	2	planned the study, designed the study, initiated the study, took part in the statistical analyses, interpreted the data, and revised the paper	planned the study, designed the study, initiated the study, took part in the statistical analyses, interpreted the data, and revised the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Review & Editing	YES
4160608	25328711	Melissa Voigt Hansen	2	had full access to all the data in the study, take responsibility for the integrity of the data and the accuracy of the data analysis, and had final responsibility for the decision to submit for publication|planned the study, designed the study, initiated the study, collected the data, analyzed and interpreted most of the data, prepared the first draft of the paper, and revised and coordinated revision of the paper	had full access to all the data in the study, take responsibility for the integrity of the data and the accuracy of the data analysis, and had final responsibility for the decision to submit for publication	Analyzed the data	Data curation|Formal analysis	YES
4160608	25328711	Melissa Voigt Hansen	2	had full access to all the data in the study, take responsibility for the integrity of the data and the accuracy of the data analysis, and had final responsibility for the decision to submit for publication|planned the study, designed the study, initiated the study, collected the data, analyzed and interpreted most of the data, prepared the first draft of the paper, and revised and coordinated revision of the paper	planned the study, designed the study, initiated the study, collected the data, analyzed and interpreted most of the data, prepared the first draft of the paper, and revised and coordinated revision of the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Project administration|Writing - Original Draft|Writing - Review & Editing	YES
4160608	25328711	Michael Tvilling Madsen	2	collected the data and revised the paper	collected the data and revised the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4160608	25328711	Susanne Bokmand	2	planned the study and revised the paper	planned the study and revised the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5319194	28219337	A-YL	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
5319194	28219337	B-LZ	PLoS52	helped with paper writing and graph making	helped with paper writing and graph making	Wrote the paper	-	YES
5319194	28219337	BT	PLoS52	helped with brain slice preparation and neuronal isolation	helped with brain slice preparation and neuronal isolation	Performed the experiments	Investigation	YES
5319194	28219337	DL	PLoS52	helped with brain slice preparation and neuronal isolation	helped with brain slice preparation and neuronal isolation	Performed the experiments	Investigation	YES
5319194	28219337	G-JC	PLoS52	designed research|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
5319194	28219337	G-JC	PLoS52	designed research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5319194	28219337	JY	PLoS52	performed research|analyzed data|wrote the paper	performed research	Performed the experiments	Investigation	YES
5319194	28219337	JY	PLoS52	performed research|analyzed data|wrote the paper	analyzed data	Analyzed the data	Formal analysis	YES
5319194	28219337	JY	PLoS52	performed research|analyzed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5319194	28219337	X-FW	PLoS52	helped with paper writing and graph making	helped with paper writing and graph making	Wrote the paper	-	YES
5319194	28219337	ZY	PLoS52	designed research	designed research	Conceived and designed the experiments	Methodology	YES
5045969	27702430	APB	2	contributed to the study design and data collection|conducted the iterative analyses	contributed to the study design and data collection	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources	YES
5045969	27702430	APB	2	contributed to the study design and data collection|conducted the iterative analyses	conducted the iterative analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5045969	27702430	AR	2	contributed to the study design and data collection|conducted the iterative analyses	contributed to the study design and data collection	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources	YES
5045969	27702430	AR	2	contributed to the study design and data collection|conducted the iterative analyses	conducted the iterative analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5045969	27702430	JG	2	conducted the iterative analyses	conducted the iterative analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5045969	27702430	JM	2	contributed to the study design and data collection|conducted the iterative analyses	contributed to the study design and data collection	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources	YES
5045969	27702430	JM	2	contributed to the study design and data collection|conducted the iterative analyses	conducted the iterative analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5045969	27702430	KG	2	contributed to the study design and data collection|conducted the iterative analyses	contributed to the study design and data collection	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources	YES
5045969	27702430	KG	2	contributed to the study design and data collection|conducted the iterative analyses	conducted the iterative analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5045969	27702430	RGP	2	conceptualized the research question|contributed to the study design and data collection|conducted the iterative analyses	conceptualized the research question	Conceived and designed the experiments	Conceptualization	YES
5045969	27702430	RGP	2	conceptualized the research question|contributed to the study design and data collection|conducted the iterative analyses	contributed to the study design and data collection	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources	YES
5045969	27702430	RGP	2	conceptualized the research question|contributed to the study design and data collection|conducted the iterative analyses	conducted the iterative analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5045969	27702430	VT	2	conducted the iterative analyses	conducted the iterative analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5563404	28868055	AF	2	collected phenotypic data|revised the manuscript	collected phenotypic data	Performed the experiments	Investigation	YES
5563404	28868055	AF	2	collected phenotypic data|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5563404	28868055	DH	2	collected phenotypic data	collected phenotypic data	Performed the experiments	Investigation	YES
5563404	28868055	DP	2	conceptualized the analysis|performed the analyses and wrote the manuscript|revised the manuscript	conceptualized the analysis	Conceived and designed the experiments	Conceptualization	YES
5563404	28868055	DP	2	conceptualized the analysis|performed the analyses and wrote the manuscript|revised the manuscript	performed the analyses and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5563404	28868055	DP	2	conceptualized the analysis|performed the analyses and wrote the manuscript|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5563404	28868055	EC	2	collected phenotypic data|revised the manuscript	collected phenotypic data	Performed the experiments	Investigation	YES
5563404	28868055	EC	2	collected phenotypic data|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5563404	28868055	GW	2	collected phenotypic data|revised the manuscript	collected phenotypic data	Performed the experiments	Investigation	YES
5563404	28868055	GW	2	collected phenotypic data|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5563404	28868055	JH	2	collected phenotypic data	collected phenotypic data	Performed the experiments	Investigation	YES
5563404	28868055	JW	2	conceived the experimental design|collected phenotypic data|conceptualized the analysis|performed the analyses and wrote the manuscript|revised the manuscript	conceived the experimental design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5563404	28868055	JW	2	conceived the experimental design|collected phenotypic data|conceptualized the analysis|performed the analyses and wrote the manuscript|revised the manuscript	collected phenotypic data	Performed the experiments	Investigation	YES
5563404	28868055	JW	2	conceived the experimental design|collected phenotypic data|conceptualized the analysis|performed the analyses and wrote the manuscript|revised the manuscript	conceptualized the analysis	Conceived and designed the experiments	Conceptualization	YES
5563404	28868055	JW	2	conceived the experimental design|collected phenotypic data|conceptualized the analysis|performed the analyses and wrote the manuscript|revised the manuscript	performed the analyses and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5563404	28868055	JW	2	conceived the experimental design|collected phenotypic data|conceptualized the analysis|performed the analyses and wrote the manuscript|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5563404	28868055	KT	2	collected phenotypic data|revised the manuscript	collected phenotypic data	Performed the experiments	Investigation	YES
5563404	28868055	KT	2	collected phenotypic data|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5563404	28868055	MC	2	collected phenotypic data|revised the manuscript	collected phenotypic data	Performed the experiments	Investigation	YES
5563404	28868055	MC	2	collected phenotypic data|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5563404	28868055	MG	2	conceived the experimental design|collected phenotypic data|conceptualized the analysis|revised the manuscript	conceived the experimental design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5563404	28868055	MG	2	conceived the experimental design|collected phenotypic data|conceptualized the analysis|revised the manuscript	collected phenotypic data	Performed the experiments	Investigation	YES
5563404	28868055	MG	2	conceived the experimental design|collected phenotypic data|conceptualized the analysis|revised the manuscript	conceptualized the analysis	Conceived and designed the experiments	Conceptualization	YES
5563404	28868055	MG	2	conceived the experimental design|collected phenotypic data|conceptualized the analysis|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5563404	28868055	PA	2	collected phenotypic data|revised the manuscript	collected phenotypic data	Performed the experiments	Investigation	YES
5563404	28868055	PA	2	collected phenotypic data|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
6021156	30061766	PhD	2	students and performed the experiment	students and performed the experiment	Performed the experiments	Investigation	YES
6021156	30061766	Prof Bagheri	2	performed coronary angiography and analyzed its results	performed coronary angiography and analyzed its results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6021156	30061766	Prof Rasouli	2	designed and conducted the study, analyzed the data, interpreted the findings and wrote the manuscript	designed and conducted the study, analyzed the data, interpreted the findings and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
6306891	30373134	E.B.	2	contributed to all aspects of producing this article including the conceptualization, research, writing, and editing	contributed to all aspects of producing this article including the conceptualization, research, writing, and editing	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
6306891	30373134	J.C.	2	contributed to all aspects of producing this article including the conceptualization, research, writing, and editing	contributed to all aspects of producing this article including the conceptualization, research, writing, and editing	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5904781	29904608	Abdulfatah Muhamad	1	Statistical analysis	Statistical analysis	Analyzed the data	Formal analysis	YES
5904781	29904608	Hiwa Ahmed	1	Study design|Data collection|Writing first draft of manuscript	Study design	Conceived and designed the experiments	Methodology	YES
5904781	29904608	Hiwa Ahmed	1	Study design|Data collection|Writing first draft of manuscript	Data collection	Performed the experiments	Investigation	YES
5904781	29904608	Hiwa Ahmed	1	Study design|Data collection|Writing first draft of manuscript	Writing first draft of manuscript	Wrote the paper	Writing - Original Draft	YES
4406562	25902145	HM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406562	25902145	HM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406562	25902145	HM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406562	25902145	HM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406562	25902145	HM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406562	25902145	HY	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4406562	25902145	HY	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4406562	25902145	MO	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406562	25902145	MO	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406562	25902145	ZL	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4502277	26229952	Adam Ogna	PLoS52	designed the experiment|conducted the research|analyzed the data and performed the statistical analyses|wrote the paper|have primary responsibility for the final content	designed the experiment	Conceived and designed the experiments	Methodology	YES
4502277	26229952	Adam Ogna	PLoS52	designed the experiment|conducted the research|analyzed the data and performed the statistical analyses|wrote the paper|have primary responsibility for the final content	conducted the research	Performed the experiments	Investigation	YES
4502277	26229952	Adam Ogna	PLoS52	designed the experiment|conducted the research|analyzed the data and performed the statistical analyses|wrote the paper|have primary responsibility for the final content	analyzed the data and performed the statistical analyses	Analyzed the data	Formal analysis	YES
4502277	26229952	Adam Ogna	PLoS52	designed the experiment|conducted the research|analyzed the data and performed the statistical analyses|wrote the paper|have primary responsibility for the final content	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4502277	26229952	Adam Ogna	PLoS52	designed the experiment|conducted the research|analyzed the data and performed the statistical analyses|wrote the paper|have primary responsibility for the final content	have primary responsibility for the final content	-	-	NO
4502277	26229952	Alexandra Mihalache	PLoS52	conducted the research|analyzed the data and performed the statistical analyses	conducted the research	Performed the experiments	Investigation	YES
4502277	26229952	Alexandra Mihalache	PLoS52	conducted the research|analyzed the data and performed the statistical analyses	analyzed the data and performed the statistical analyses	Analyzed the data	Formal analysis	YES
4502277	26229952	Anne Cherpillod	PLoS52	conducted the research	conducted the research	Performed the experiments	Investigation	YES
4502277	26229952	Claudine Mathieu	PLoS52	conducted the research	conducted the research	Performed the experiments	Investigation	YES
4502277	26229952	Daniel Teta	PLoS52	conducted the research	conducted the research	Performed the experiments	Investigation	YES
4502277	26229952	Emilie Zuercher	PLoS52	conducted the research	conducted the research	Performed the experiments	Investigation	YES
4502277	26229952	Francoise Cornette	PLoS52	conducted the research|analyzed the data and performed the statistical analyses	conducted the research	Performed the experiments	Investigation	YES
4502277	26229952	Francoise Cornette	PLoS52	conducted the research|analyzed the data and performed the statistical analyses	analyzed the data and performed the statistical analyses	Analyzed the data	Formal analysis	YES
4502277	26229952	Georges Halabi	PLoS52	designed the experiment|conducted the research	designed the experiment	Conceived and designed the experiments	Methodology	YES
4502277	26229952	Georges Halabi	PLoS52	designed the experiment|conducted the research	conducted the research	Performed the experiments	Investigation	YES
4502277	26229952	Isabelle Bassi	PLoS52	conducted the research	conducted the research	Performed the experiments	Investigation	YES
4502277	26229952	Jose Haba-Rubio	PLoS52	designed the experiment|analyzed the data and performed the statistical analyses|wrote the paper	designed the experiment	Conceived and designed the experiments	Methodology	YES
4502277	26229952	Jose Haba-Rubio	PLoS52	designed the experiment|analyzed the data and performed the statistical analyses|wrote the paper	analyzed the data and performed the statistical analyses	Analyzed the data	Formal analysis	YES
4502277	26229952	Jose Haba-Rubio	PLoS52	designed the experiment|analyzed the data and performed the statistical analyses|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4502277	26229952	Menno Pruijm	PLoS52	designed the experiment|conducted the research|wrote the paper	designed the experiment	Conceived and designed the experiments	Methodology	YES
4502277	26229952	Menno Pruijm	PLoS52	designed the experiment|conducted the research|wrote the paper	conducted the research	Performed the experiments	Investigation	YES
4502277	26229952	Menno Pruijm	PLoS52	designed the experiment|conducted the research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4502277	26229952	Michel Burnier	PLoS52	designed the experiment|wrote the paper	designed the experiment	Conceived and designed the experiments	Methodology	YES
4502277	26229952	Michel Burnier	PLoS52	designed the experiment|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4502277	26229952	Olivier Phan	PLoS52	designed the experiment|conducted the research	designed the experiment	Conceived and designed the experiments	Methodology	YES
4502277	26229952	Olivier Phan	PLoS52	designed the experiment|conducted the research	conducted the research	Performed the experiments	Investigation	YES
4502277	26229952	Raphael Heinzer	PLoS52	designed the experiment|analyzed the data and performed the statistical analyses|wrote the paper|have primary responsibility for the final content	designed the experiment	Conceived and designed the experiments	Methodology	YES
4502277	26229952	Raphael Heinzer	PLoS52	designed the experiment|analyzed the data and performed the statistical analyses|wrote the paper|have primary responsibility for the final content	analyzed the data and performed the statistical analyses	Analyzed the data	Formal analysis	YES
4502277	26229952	Raphael Heinzer	PLoS52	designed the experiment|analyzed the data and performed the statistical analyses|wrote the paper|have primary responsibility for the final content	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4502277	26229952	Raphael Heinzer	PLoS52	designed the experiment|analyzed the data and performed the statistical analyses|wrote the paper|have primary responsibility for the final content	have primary responsibility for the final content	-	-	NO
4502277	26229952	Roberto Bullani	PLoS52	conducted the research	conducted the research	Performed the experiments	Investigation	YES
4502277	26229952	Thierry Gauthier	PLoS52	conducted the research	conducted the research	Performed the experiments	Investigation	YES
4502277	26229952	Valentina Forni Ogna	PLoS52	designed the experiment|conducted the research|analyzed the data and performed the statistical analyses|wrote the paper|have primary responsibility for the final content	designed the experiment	Conceived and designed the experiments	Methodology	YES
4502277	26229952	Valentina Forni Ogna	PLoS52	designed the experiment|conducted the research|analyzed the data and performed the statistical analyses|wrote the paper|have primary responsibility for the final content	conducted the research	Performed the experiments	Investigation	YES
4502277	26229952	Valentina Forni Ogna	PLoS52	designed the experiment|conducted the research|analyzed the data and performed the statistical analyses|wrote the paper|have primary responsibility for the final content	analyzed the data and performed the statistical analyses	Analyzed the data	Formal analysis	YES
4502277	26229952	Valentina Forni Ogna	PLoS52	designed the experiment|conducted the research|analyzed the data and performed the statistical analyses|wrote the paper|have primary responsibility for the final content	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4502277	26229952	Valentina Forni Ogna	PLoS52	designed the experiment|conducted the research|analyzed the data and performed the statistical analyses|wrote the paper|have primary responsibility for the final content	have primary responsibility for the final content	-	-	NO
5055615	27717409	AD	2	reviewed the manuscript for editing	reviewed the manuscript for editing	Wrote the paper	Writing - Review & Editing	YES
5055615	27717409	CM	2	contributed to the conceptualization of the review article and the methodology of selecting articles based on inclusion and exclusion criteria, summarized results and helped with writing the manuscript	contributed to the conceptualization of the review article and the methodology of selecting articles based on inclusion and exclusion criteria, summarized results and helped with writing the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5055615	27717409	IM	2	reviewed the manuscript for editing	reviewed the manuscript for editing	Wrote the paper	Writing - Review & Editing	YES
5055615	27717409	JA	2	reviewed the manuscript for editing	reviewed the manuscript for editing	Wrote the paper	Writing - Review & Editing	YES
5055615	27717409	NTT	2	contributed to the conceptualization of the review article, picked search terms with the aid of indiana university school of medicine librarians, reviewed articles based on inclusion and exclusion criteria, summarized the results and aided in writing portions of the manuscript	contributed to the conceptualization of the review article, picked search terms with the aid of indiana university school of medicine librarians, reviewed articles based on inclusion and exclusion criteria, summarized the results and aided in writing portions of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
5055615	27717409	RV	2	contributed to the conceptualization of the review, aided in final selection of articles based on inclusion and exclusion criteria and thoroughly edited the manuscript	contributed to the conceptualization of the review, aided in final selection of articles based on inclusion and exclusion criteria and thoroughly edited the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5055615	27717409	WN	2	reviewed the manuscript for editing	reviewed the manuscript for editing	Wrote the paper	Writing - Review & Editing	YES
5566580	28871265	AD	7	planned the experiments|conducted the experiments|analyzed the data and compiled, reviewed and edited the manuscript	planned the experiments	Conceived and designed the experiments	Conceptualization	YES
5566580	28871265	AD	7	planned the experiments|conducted the experiments|analyzed the data and compiled, reviewed and edited the manuscript	conducted the experiments	Performed the experiments	Investigation	YES
5566580	28871265	AD	7	planned the experiments|conducted the experiments|analyzed the data and compiled, reviewed and edited the manuscript	analyzed the data and compiled, reviewed and edited the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5566580	28871265	AS	7	conducted the experiments|analyzed the data and compiled, reviewed and edited the manuscript	conducted the experiments	Performed the experiments	Investigation	YES
5566580	28871265	AS	7	conducted the experiments|analyzed the data and compiled, reviewed and edited the manuscript	analyzed the data and compiled, reviewed and edited the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5566580	28871265	GS	7	planned the experiments|conducted the experiments|analyzed the data and compiled, reviewed and edited the manuscript	planned the experiments	Conceived and designed the experiments	Conceptualization	YES
5566580	28871265	GS	7	planned the experiments|conducted the experiments|analyzed the data and compiled, reviewed and edited the manuscript	conducted the experiments	Performed the experiments	Investigation	YES
5566580	28871265	GS	7	planned the experiments|conducted the experiments|analyzed the data and compiled, reviewed and edited the manuscript	analyzed the data and compiled, reviewed and edited the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5566580	28871265	JA	7	conducted the experiments	conducted the experiments	Performed the experiments	Investigation	YES
5566580	28871265	NS	7	planned the experiments|analyzed the data and compiled, reviewed and edited the manuscript	planned the experiments	Conceived and designed the experiments	Conceptualization	YES
5566580	28871265	NS	7	planned the experiments|analyzed the data and compiled, reviewed and edited the manuscript	analyzed the data and compiled, reviewed and edited the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5566580	28871265	PK	7	analyzed the data and compiled, reviewed and edited the manuscript	analyzed the data and compiled, reviewed and edited the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5566580	28871265	SC	7	planned the experiments	planned the experiments	Conceived and designed the experiments	Conceptualization	YES
5566580	28871265	SD	7	planned the experiments|conducted the experiments	planned the experiments	Conceived and designed the experiments	Conceptualization	YES
5566580	28871265	SD	7	planned the experiments|conducted the experiments	conducted the experiments	Performed the experiments	Investigation	YES
5566580	28871265	ST	7	conducted the experiments|analyzed the data and compiled, reviewed and edited the manuscript	conducted the experiments	Performed the experiments	Investigation	YES
5566580	28871265	ST	7	conducted the experiments|analyzed the data and compiled, reviewed and edited the manuscript	analyzed the data and compiled, reviewed and edited the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5322657	28228125	AA	2	prepared the rna, analyzed the data, and cowrote the manuscript	prepared the rna, analyzed the data, and cowrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5322657	28228125	HJ	2	conceived the study, analyzed the data, and cowrote the manuscript	conceived the study, analyzed the data, and cowrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
5322657	28228125	KSK	2	performed the protein kinase studies	performed the protein kinase studies	Performed the experiments	Investigation	YES
6021158	30061760	AA	1	Study conception and design|Acquisition of data|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content	Study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6021158	30061760	AA	1	Study conception and design|Acquisition of data|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content	Acquisition of data	Performed the experiments	Investigation	YES
6021158	30061760	AA	1	Study conception and design|Acquisition of data|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content	Drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
6021158	30061760	AA	1	Study conception and design|Acquisition of data|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content	Critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
6021158	30061760	HDK	1	Study conception and design|Statistical analysis and interpretation of data|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content	Study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6021158	30061760	HDK	1	Study conception and design|Statistical analysis and interpretation of data|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content	Statistical analysis and interpretation of data	Analyzed the data	Formal analysis	YES
6021158	30061760	HDK	1	Study conception and design|Statistical analysis and interpretation of data|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content	Drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
6021158	30061760	HDK	1	Study conception and design|Statistical analysis and interpretation of data|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content	Critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
6021158	30061760	MF	1	Study conception and design|Acquisition of data|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content	Study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6021158	30061760	MF	1	Study conception and design|Acquisition of data|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content	Acquisition of data	Performed the experiments	Investigation	YES
6021158	30061760	MF	1	Study conception and design|Acquisition of data|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content	Drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
6021158	30061760	MF	1	Study conception and design|Acquisition of data|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content	Critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
6021158	30061760	MK	1	Study conception and design|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content	Study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6021158	30061760	MK	1	Study conception and design|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content	Drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
6021158	30061760	MK	1	Study conception and design|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content	Critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
6021158	30061760	RA	1	Study conception and design|Acquisition of data|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content	Study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6021158	30061760	RA	1	Study conception and design|Acquisition of data|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content	Acquisition of data	Performed the experiments	Investigation	YES
6021158	30061760	RA	1	Study conception and design|Acquisition of data|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content	Drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
6021158	30061760	RA	1	Study conception and design|Acquisition of data|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content	Critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5904784	29904607	Efrain Riveros-Perez	7	Review of literature and construction of the manuscript	Review of literature and construction of the manuscript	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
5904784	29904607	Ricardo Riveros	7	Construction of the manuscript and review	Construction of the manuscript and review	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4406580	25901608	CS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4406580	25901608	HS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406580	25901608	HS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406580	25901608	HS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406580	25901608	HS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406580	25901608	HW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4406580	25901608	XT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406580	25901608	XT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406580	25901608	XT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406580	25901608	XT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5322666	28228130	GXL	2	collected plant materials, carried out computational analysis and wrote the manuscript	collected plant materials, carried out computational analysis and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5322666	28228130	LL	2	contributed to the design of the research	contributed to the design of the research	Conceived and designed the experiments	Methodology	YES
5322666	28228130	PHT	2	conceived and designed the research	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5322666	28228130	TJR	2	helped to draft and revise the manuscript	helped to draft and revise the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5322666	28228130	WHH	2	collected data and performed the experiments	collected data and performed the experiments	Performed the experiments	Investigation	YES
5322666	28228130	XTL	2	helped to draft and revise the manuscript	helped to draft and revise the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5322666	28228130	YC	2	contributed to the design of the research	contributed to the design of the research	Conceived and designed the experiments	Methodology	YES
5322666	28228130	ZN	2	collected data and performed the experiments	collected data and performed the experiments	Performed the experiments	Investigation	YES
5061879	27733238	CG	2	acquired, analyzed and interpreted the data|revised the manuscript critically for important intellectual content|have given final approval for the version to be published	acquired, analyzed and interpreted the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5061879	27733238	CG	2	acquired, analyzed and interpreted the data|revised the manuscript critically for important intellectual content|have given final approval for the version to be published	revised the manuscript critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5061879	27733238	CG	2	acquired, analyzed and interpreted the data|revised the manuscript critically for important intellectual content|have given final approval for the version to be published	have given final approval for the version to be published	-	-	NO
5061879	27733238	DSK	2	acquired, analyzed and interpreted the data|revised the manuscript critically for important intellectual content|have given final approval for the version to be published	acquired, analyzed and interpreted the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5061879	27733238	DSK	2	acquired, analyzed and interpreted the data|revised the manuscript critically for important intellectual content|have given final approval for the version to be published	revised the manuscript critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5061879	27733238	DSK	2	acquired, analyzed and interpreted the data|revised the manuscript critically for important intellectual content|have given final approval for the version to be published	have given final approval for the version to be published	-	-	NO
5061879	27733238	KHM	2	acquired, analyzed and interpreted the data|revised the manuscript critically for important intellectual content|have given final approval for the version to be published	acquired, analyzed and interpreted the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5061879	27733238	KHM	2	acquired, analyzed and interpreted the data|revised the manuscript critically for important intellectual content|have given final approval for the version to be published	revised the manuscript critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5061879	27733238	KHM	2	acquired, analyzed and interpreted the data|revised the manuscript critically for important intellectual content|have given final approval for the version to be published	have given final approval for the version to be published	-	-	NO
5061879	27733238	KM	2	revised the manuscript critically for important intellectual content|have given final approval for the version to be published	revised the manuscript critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5061879	27733238	KM	2	revised the manuscript critically for important intellectual content|have given final approval for the version to be published	have given final approval for the version to be published	-	-	NO
5061879	27733238	KMM	2	acquired, analyzed and interpreted the data|revised the manuscript critically for important intellectual content|have given final approval for the version to be published	acquired, analyzed and interpreted the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5061879	27733238	KMM	2	acquired, analyzed and interpreted the data|revised the manuscript critically for important intellectual content|have given final approval for the version to be published	revised the manuscript critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5061879	27733238	KMM	2	acquired, analyzed and interpreted the data|revised the manuscript critically for important intellectual content|have given final approval for the version to be published	have given final approval for the version to be published	-	-	NO
5566963	28871271	BP	2	is the main mind behind the totipotency theory	is the main mind behind the totipotency theory	-	-	NO
5566963	28871271	NC	2	is an expert in coffee embryogenesis	is an expert in coffee embryogenesis	-	-	NO
5566963	28871271	SC	2	behind the integration of omics technologies	behind the integration of omics technologies	-	-	NO
5566963	28871271	The authors	2	jointly wrote the paper	jointly wrote the paper	Wrote the paper	Writing - Original Draft	YES
5911665	29692892	Aysha Habib Khan	2	conceive the idea, design the study, data gathering, analysis & write up	conceive the idea, design the study, data gathering, analysis & write up	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology	YES
5911665	29692892	Dr Sibtain	2	data gathering & write-up	data gathering & write-up	Wrote the paper	-	YES
5911665	29692892	Lena Jafri	2	data gathering, analysis & write-up	data gathering, analysis & write-up	Analyzed the data|Wrote the paper	Formal analysis	YES
5911665	29692892	Shahryar Noordin	2	critical review of the manuscript and write-up	critical review of the manuscript and write-up	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6306909	30544848	H.E.S.	2	contributed to writing of the paper and statistical analyses	contributed to writing of the paper and statistical analyses	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6306909	30544848	J.J.S.	2	contributed to writing of the paper and statistical analyses	contributed to writing of the paper and statistical analyses	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6306909	30544848	S.K.	2	led on project conceptualization and administration, methodology creation, data collection, data input and statistical analyses and is the primary author of the paper	led on project conceptualization and administration, methodology creation, data collection, data input and statistical analyses and is the primary author of the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Project administration|Writing - Original Draft	YES
4406581	25902263	EVL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406581	25902263	EVL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406581	25902263	EVL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406581	25902263	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406581	25902263	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406581	25902263	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406581	25902263	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406581	25902263	JH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406581	25902263	JH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406581	25902263	JH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406581	25902263	KV	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406581	25902263	KV	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406581	25902263	KV	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406581	25902263	MVS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406581	25902263	MVS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406581	25902263	MVS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5322787	28219342	BJW	2	carried out the functional annotation analysis and verified experiment of mirna and their target genes	carried out the functional annotation analysis and verified experiment of mirna and their target genes	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation|Validation	YES
5322787	28219342	TYF	2	carried out the functional annotation analysis and verified experiment of mirna and their target genes	carried out the functional annotation analysis and verified experiment of mirna and their target genes	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation|Validation	YES
5566965	28871268	ES	2	analyzed the data and complement the writing	analyzed the data and complement the writing	Analyzed the data|Wrote the paper	Formal analysis	YES
5566965	28871268	JP	2	designed the research, collected and analyzed the data and wrote the manuscript	designed the research, collected and analyzed the data and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5566965	28871268	MS	2	analyzed the data and complement the writing	analyzed the data and complement the writing	Analyzed the data|Wrote the paper	Formal analysis	YES
5566965	28871268	PR	2	conceived the original project and research plans and co-wrote the manuscript	conceived the original project and research plans and co-wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
6021161	30061769	Each author	2	participated in each step of research	participated in each step of research	-	-	NO
5566966	28871270	JZ	PLoS52	designed the experiments|analyzed the data and wrote the paper	designed the experiments	Conceived and designed the experiments	Methodology	YES
5566966	28871270	JZ	PLoS52	designed the experiments|analyzed the data and wrote the paper	analyzed the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5566966	28871270	LC	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5566966	28871270	LM	PLoS52	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5566966	28871270	LY	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5566966	28871270	MM	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5566966	28871270	MW	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5566966	28871270	RB	PLoS52	analyzed the data and wrote the paper	analyzed the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5566966	28871270	SL	PLoS52	analyzed the data and wrote the paper	analyzed the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5566966	28871270	YW	PLoS52	designed the experiments|performed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5566966	28871270	YW	PLoS52	designed the experiments|performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5065689	27741954	CAM	2	helped with literature searches and made significant edits to the manuscript	helped with literature searches and made significant edits to the manuscript	Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5065689	27741954	EJA	2	helped to conceptualize and revise the manuscript	helped to conceptualize and revise the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5065689	27741954	JJ	2	conceptualized and wrote the manuscript	conceptualized and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5065689	27741954	RH	2	helped with revisions to the manuscript	helped with revisions to the manuscript	Wrote the paper	Writing - Review & Editing	YES
5065689	27741954	RHR	2	helped with revisions to the manuscript	helped with revisions to the manuscript	Wrote the paper	Writing - Review & Editing	YES
6306913	30274320	A.H.	CRediT	methodology|writing--review and editing	methodology	Performed the experiments	Methodology	YES
6306913	30274320	A.H.	CRediT	methodology|writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6306913	30274320	A.U.	CRediT	investigation|data curation|writing--original draft preparation	investigation	Performed the experiments	Investigation	YES
6306913	30274320	A.U.	CRediT	investigation|data curation|writing--original draft preparation	data curation	Analyzed the data	Data curation	YES
6306913	30274320	A.U.	CRediT	investigation|data curation|writing--original draft preparation	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6306913	30274320	B.E.	CRediT	investigation|data curation|writing--original draft preparation	investigation	Performed the experiments	Investigation	YES
6306913	30274320	B.E.	CRediT	investigation|data curation|writing--original draft preparation	data curation	Analyzed the data	Data curation	YES
6306913	30274320	B.E.	CRediT	investigation|data curation|writing--original draft preparation	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6306913	30274320	B.G.	CRediT	investigation|data curation	investigation	Performed the experiments	Investigation	YES
6306913	30274320	B.G.	CRediT	investigation|data curation	data curation	Analyzed the data	Data curation	YES
6306913	30274320	K.H.	CRediT	investigation|data curation|writing--original draft preparation	investigation	Performed the experiments	Investigation	YES
6306913	30274320	K.H.	CRediT	investigation|data curation|writing--original draft preparation	data curation	Analyzed the data	Data curation	YES
6306913	30274320	K.H.	CRediT	investigation|data curation|writing--original draft preparation	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6306913	30274320	M.S.S.	CRediT	formal analysis|writing--review and editing	formal analysis	Analyzed the data	Formal analysis	YES
6306913	30274320	M.S.S.	CRediT	formal analysis|writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6306913	30274320	R.S.	CRediT	methodology|writing--review and editing	methodology	Performed the experiments	Methodology	YES
6306913	30274320	R.S.	CRediT	methodology|writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6306913	30274320	S.S.	CRediT	Conceptualization|methodology|formal analysis|investigation|data curation|writing--original draft preparation|writing--review and editing|supervision	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6306913	30274320	S.S.	CRediT	Conceptualization|methodology|formal analysis|investigation|data curation|writing--original draft preparation|writing--review and editing|supervision	methodology	Performed the experiments	Methodology	YES
6306913	30274320	S.S.	CRediT	Conceptualization|methodology|formal analysis|investigation|data curation|writing--original draft preparation|writing--review and editing|supervision	formal analysis	Analyzed the data	Formal analysis	YES
6306913	30274320	S.S.	CRediT	Conceptualization|methodology|formal analysis|investigation|data curation|writing--original draft preparation|writing--review and editing|supervision	investigation	Performed the experiments	Investigation	YES
6306913	30274320	S.S.	CRediT	Conceptualization|methodology|formal analysis|investigation|data curation|writing--original draft preparation|writing--review and editing|supervision	data curation	Analyzed the data	Data curation	YES
6306913	30274320	S.S.	CRediT	Conceptualization|methodology|formal analysis|investigation|data curation|writing--original draft preparation|writing--review and editing|supervision	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6306913	30274320	S.S.	CRediT	Conceptualization|methodology|formal analysis|investigation|data curation|writing--original draft preparation|writing--review and editing|supervision	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
6306913	30274320	S.S.	CRediT	Conceptualization|methodology|formal analysis|investigation|data curation|writing--original draft preparation|writing--review and editing|supervision	supervision	-	Supervision	YES
6306913	30274320	V.P.	CRediT	investigation|data curation|writing--original draft preparation	investigation	Performed the experiments	Investigation	YES
6306913	30274320	V.P.	CRediT	investigation|data curation|writing--original draft preparation	data curation	Analyzed the data	Data curation	YES
6306913	30274320	V.P.	CRediT	investigation|data curation|writing--original draft preparation	writing--original draft preparation	Wrote the paper	Writing - Original Draft	YES
6021162	30061764	DiP	2	participate in design of the study and performed of the study	participate in design of the study and performed of the study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6021162	30061764	DrP	2	performed the statistical analysis, participated in its design and coordination and helped to draft the manuscript	performed the statistical analysis, participated in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Project administration|Writing - Original Draft	YES
6021162	30061764	HPJ	2	performed of the study, participated in the sequence alignment and drafted the manuscript	performed of the study, participated in the sequence alignment and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6021162	30061764	JP	2	participated in the design of the study and performed of the study	participated in the design of the study and performed of the study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6021162	30061764	RJ	2	participated in the design of the study and performed of the study	participated in the design of the study and performed of the study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4406584	25902062	BV	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406584	25902062	BV	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406584	25902062	BV	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406584	25902062	KL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406584	25902062	KL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406584	25902062	KL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406584	25902062	KL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406584	25902062	KL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406584	25902062	PR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406584	25902062	PR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406584	25902062	PR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406584	25902062	PR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406584	25902062	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406584	25902062	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406584	25902062	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406584	25902062	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5324198	28231761	BL	2	carried out the bioinformatical and statistical analyses and wrote the manuscript|conducted the wet lab experiments	carried out the bioinformatical and statistical analyses and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5324198	28231761	BL	2	carried out the bioinformatical and statistical analyses and wrote the manuscript|conducted the wet lab experiments	conducted the wet lab experiments	Performed the experiments	Investigation	YES
5324198	28231761	CB	2	contributed to conceive and design the study	contributed to conceive and design the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5324198	28231761	CS	2	conducted the wet lab experiments	conducted the wet lab experiments	Performed the experiments	Investigation	YES
5324198	28231761	MFO	2	was responsible for overall research management	was responsible for overall research management	-	-	NO
5324198	28231761	MM	2	conducted the wet lab experiments	conducted the wet lab experiments	Performed the experiments	Investigation	YES
5324198	28231761	NP	2	assisted to the data mining and manuscript writing	assisted to the data mining and manuscript writing	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5911668	29692889	A Agha	7	Concept, critical review of each draft and suggestions for revisions, approval of final manuscript	Concept, critical review of each draft and suggestions for revisions, approval of final manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
5911668	29692889	Buket Gundogan	7	manuscript revision	manuscript revision	Wrote the paper	Writing - Review & Editing	YES
5911668	29692889	Mimi Reem Farwana	7	manuscript revision	manuscript revision	Wrote the paper	Writing - Review & Editing	YES
5911668	29692889	R Borrelli	7	concept, manuscript design, writing manuscript content, revisions	concept, manuscript design, writing manuscript content, revisions	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
5911668	29692889	Thomas Edward Pidgeon	7	Concept, critical review of each draft and suggestions for revisions, approval of final manuscript. Riaz	Concept, critical review of each draft and suggestions for revisions, approval of final manuscript. Riaz	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
5911668	29692889	Yasser Al Omran	7	manuscript revision	manuscript revision	Wrote the paper	Writing - Review & Editing	YES
5069281	27756450	All authors	2	provided input to subsequent drafts of the paper and all approved the final version	provided input to subsequent drafts of the paper and all approved the final version	Wrote the paper	Writing - Original Draft	YES
5069281	27756450	JT	2	initiated and conceived the study|planned the analyses	initiated and conceived the study	Conceived and designed the experiments	Conceptualization	YES
5069281	27756450	JT	2	initiated and conceived the study|planned the analyses	planned the analyses	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
5069281	27756450	MD	2	initiated and conceived the study	initiated and conceived the study	Conceived and designed the experiments	Conceptualization	YES
5069281	27756450	ML	2	planned the analyses|conducted the literature searches	planned the analyses	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
5069281	27756450	ML	2	planned the analyses|conducted the literature searches	conducted the literature searches	Performed the experiments	Formal analysis|Investigation	YES
5069281	27756450	QM	2	planned the analyses|extracted the data|synthesized the qualitative data, created cerqual table and wrote the first draft of the paper	planned the analyses	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
5069281	27756450	QM	2	planned the analyses|extracted the data|synthesized the qualitative data, created cerqual table and wrote the first draft of the paper	extracted the data	Performed the experiments	Investigation	YES
5069281	27756450	QM	2	planned the analyses|extracted the data|synthesized the qualitative data, created cerqual table and wrote the first draft of the paper	synthesized the qualitative data, created cerqual table and wrote the first draft of the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5069281	27756450	RB	2	initiated and conceived the study	initiated and conceived the study	Conceived and designed the experiments	Conceptualization	YES
5069281	27756450	ZR	2	planned the analyses|extracted the data	planned the analyses	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
5069281	27756450	ZR	2	planned the analyses|extracted the data	extracted the data	Performed the experiments	Investigation	YES
5566972	28871267	Ph.D.	2	thesis in which this review is based	thesis in which this review is based	-	-	NO
6306925	30360517	A.B.	CRediT	Methodology|Resources	Methodology	Performed the experiments	Methodology	YES
6306925	30360517	A.B.	CRediT	Methodology|Resources	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6306925	30360517	A.Q.B.	CRediT	Writing-review & editing	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6306925	30360517	H.A.	CRediT	Validation	Validation	Performed the experiments	Validation	YES
6306925	30360517	I.U.	CRediT	Writing-original draft preparation	Writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
6306925	30360517	I.U.R.	CRediT	Conceptualization|Methodology|Software|Validation|Formal analysis|Investigation|Resources|Data curation|Project administration	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6306925	30360517	I.U.R.	CRediT	Conceptualization|Methodology|Software|Validation|Formal analysis|Investigation|Resources|Data curation|Project administration	Methodology	Performed the experiments	Methodology	YES
6306925	30360517	I.U.R.	CRediT	Conceptualization|Methodology|Software|Validation|Formal analysis|Investigation|Resources|Data curation|Project administration	Software	Contributed reagents/materials/analysis tools	Software	YES
6306925	30360517	I.U.R.	CRediT	Conceptualization|Methodology|Software|Validation|Formal analysis|Investigation|Resources|Data curation|Project administration	Validation	Performed the experiments	Validation	YES
6306925	30360517	I.U.R.	CRediT	Conceptualization|Methodology|Software|Validation|Formal analysis|Investigation|Resources|Data curation|Project administration	Formal analysis	Analyzed the data	Formal analysis	YES
6306925	30360517	I.U.R.	CRediT	Conceptualization|Methodology|Software|Validation|Formal analysis|Investigation|Resources|Data curation|Project administration	Investigation	Performed the experiments	Investigation	YES
6306925	30360517	I.U.R.	CRediT	Conceptualization|Methodology|Software|Validation|Formal analysis|Investigation|Resources|Data curation|Project administration	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6306925	30360517	I.U.R.	CRediT	Conceptualization|Methodology|Software|Validation|Formal analysis|Investigation|Resources|Data curation|Project administration	Data curation	Analyzed the data	Data curation	YES
6306925	30360517	I.U.R.	CRediT	Conceptualization|Methodology|Software|Validation|Formal analysis|Investigation|Resources|Data curation|Project administration	Project administration	-	Project administration	YES
6306925	30360517	J.A.D.	CRediT	Writing-review & editing	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6306925	30360517	M.M.A.	CRediT	Conceptualization|Data curation	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6306925	30360517	M.M.A.	CRediT	Conceptualization|Data curation	Data curation	Analyzed the data	Data curation	YES
6306925	30360517	T.M.K.	CRediT	Conceptualization|Methodology|Software|Formal analysis|Writing-review & editing|Visualization|Supervision|Project administration	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6306925	30360517	T.M.K.	CRediT	Conceptualization|Methodology|Software|Formal analysis|Writing-review & editing|Visualization|Supervision|Project administration	Methodology	Performed the experiments	Methodology	YES
6306925	30360517	T.M.K.	CRediT	Conceptualization|Methodology|Software|Formal analysis|Writing-review & editing|Visualization|Supervision|Project administration	Software	Contributed reagents/materials/analysis tools	Software	YES
6306925	30360517	T.M.K.	CRediT	Conceptualization|Methodology|Software|Formal analysis|Writing-review & editing|Visualization|Supervision|Project administration	Formal analysis	Analyzed the data	Formal analysis	YES
6306925	30360517	T.M.K.	CRediT	Conceptualization|Methodology|Software|Formal analysis|Writing-review & editing|Visualization|Supervision|Project administration	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6306925	30360517	T.M.K.	CRediT	Conceptualization|Methodology|Software|Formal analysis|Writing-review & editing|Visualization|Supervision|Project administration	Visualization	Analyzed the data	Visualization	YES
6306925	30360517	T.M.K.	CRediT	Conceptualization|Methodology|Software|Formal analysis|Writing-review & editing|Visualization|Supervision|Project administration	Supervision	-	Supervision	YES
6306925	30360517	T.M.K.	CRediT	Conceptualization|Methodology|Software|Formal analysis|Writing-review & editing|Visualization|Supervision|Project administration	Project administration	-	Project administration	YES
6306925	30360517	Z.A.	CRediT	Resources|Data curation	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6306925	30360517	Z.A.	CRediT	Resources|Data curation	Data curation	Analyzed the data	Data curation	YES
4502284	26229962	Qiang Wang	PLoS52	wrote the paper|contributed equally to this work	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4502284	26229962	Qiang Wang	PLoS52	wrote the paper|contributed equally to this work	contributed equally to this work	-	-	NO
4502284	26229962	Qiang Zhou	PLoS52	contributed equally to this work	contributed equally to this work	-	-	NO
4502284	26229962	Yuan Xu	PLoS52	wrote the paper|contributed equally to this work	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4502284	26229962	Yuan Xu	PLoS52	wrote the paper|contributed equally to this work	contributed equally to this work	-	-	NO
4502284	26229962	Yue Zhou	PLoS52	contributed equally to this work	contributed equally to this work	-	-	NO
6021163	30061765	All authors	2	of this manuscript had equal substantial contribution to conception and design, to acquisition of data, to analysis and interpretation of data, in drafting the article, in critically revising the article for important intellectual content, and in final approval of the version to be published	of this manuscript had equal substantial contribution to conception and design, to acquisition of data, to analysis and interpretation of data, in drafting the article, in critically revising the article for important intellectual content, and in final approval of the version to be published	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5911669	29692894	Bassam Masri	7	data analysis, writing	data analysis, writing	Analyzed the data|Wrote the paper	Formal analysis	YES
5911669	29692894	Riaz Lakdawala	7	data analysis, writing	data analysis, writing	Analyzed the data|Wrote the paper	Formal analysis	YES
5911669	29692894	Shahryar Noordin	7	study design, data collection, data analysis, writing	study design, data collection, data analysis, writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology	YES
5071746	27760688	All authors	2	contributed to the outline of this paper|commented on drafts of the paper and agreed with the final version	contributed to the outline of this paper	-	-	NO
5071746	27760688	All authors	2	contributed to the outline of this paper|commented on drafts of the paper and agreed with the final version	commented on drafts of the paper and agreed with the final version	Wrote the paper	Writing - Original Draft	YES
5071746	27760688	IZ	2	assumed primary responsibility for writing and revising the manuscript	assumed primary responsibility for writing and revising the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5071746	27760688	YRL	2	substantially contributed to the preparation of this paper	substantially contributed to the preparation of this paper	-	-	NO
5566991	28871269	CH	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5566991	28871269	FW	PLoS52	conceived and designed the experiments|analyzed the data	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5566991	28871269	FW	PLoS52	conceived and designed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5566991	28871269	G-LW	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5566991	28871269	GL	PLoS52	contributed reagents and tools	contributed reagents and tools	Contributed reagents/materials/analysis tools	Resources	YES
5566991	28871269	MB	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5566991	28871269	QC	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5566991	28871269	QC	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5566991	28871269	SC	PLoS52	conceived and designed the experiments|analyzed the data|wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5566991	28871269	SC	PLoS52	conceived and designed the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5566991	28871269	SC	PLoS52	conceived and designed the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5566991	28871269	TH	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5566991	28871269	XG	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5566991	28871269	YL	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5566991	28871269	ZJC	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5566991	28871269	ZJC	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5566991	28871269	ZJC	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5566991	28871269	ZJC	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5566991	28871269	ZQC	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5566991	28871269	ZW	PLoS52	analyzed the data|contributed reagents and tools	analyzed the data	Analyzed the data	Formal analysis	YES
5566991	28871269	ZW	PLoS52	analyzed the data|contributed reagents and tools	contributed reagents and tools	Contributed reagents/materials/analysis tools	Resources	YES
5911670	29692890	Maxwell D. Mirande	2	was the primary contributor in writing the case report and preparing it for manuscript	was the primary contributor in writing the case report and preparing it for manuscript	Wrote the paper	Writing - Original Draft	YES
5911670	29692890	Raul A. Mirande	2	contributed by providing the clinical care to the patient during her treatment and further follow-up as well as supervising the writing of the case report	contributed by providing the clinical care to the patient during her treatment and further follow-up as well as supervising the writing of the case report	Performed the experiments|Wrote the paper	Investigation|Supervision	YES
4406585	25902199	BKK	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406585	25902199	BKK	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406585	25902199	DPK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406585	25902199	DPK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406585	25902199	MRK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406585	25902199	MRK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406585	25902199	MRK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406585	25902199	MRK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406585	25902199	RAB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406585	25902199	RAB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4406585	25902199	RAB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4406585	25902199	RAB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406585	25902199	TDC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406585	25902199	TDC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406585	25902199	TDC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406585	25902199	TDC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5324221	28231763	SXG	2	is the sole author and responsible for all aspects of this study	is the sole author and responsible for all aspects of this study	-	-	NO
4220584	25400950	All authors	2	contributed in the preparation of the paper and all authors read and approved the final paper	contributed in the preparation of the paper and all authors read and approved the final paper	-	-	NO
4220584	25400950	Carl Blomqvist	2	helped with the interpretation of the results and with drafting the paper	helped with the interpretation of the results and with drafting the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4220584	25400950	ER	2	and her2 and updated the follow-up in the cohort	and her2 and updated the follow-up in the cohort	-	-	NO
4220584	25400950	Fredrik Warnberg	2	designed the overall study, coordinated the study, and helped draft and finalise the paper	designed the overall study, coordinated the study, and helped draft and finalise the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft|Writing - Review & Editing	YES
4220584	25400950	Gunilla Christensson	2	updated the follow-up data for the patients from falun hospital	updated the follow-up data for the patients from falun hospital	-	-	NO
4220584	25400950	Marie-Louise Fjallskog	2	helped with the interpretation of the results and with drafting the paper	helped with the interpretation of the results and with drafting the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4220584	25400950	PR	2	and her2 and updated the follow-up in the cohort	and her2 and updated the follow-up in the cohort	-	-	NO
4220584	25400950	Rose-Marie Amini	2	were involved in the pathology review and scoring of stains for the neoductgenesis classification	were involved in the pathology review and scoring of stains for the neoductgenesis classification	Performed the experiments	Investigation	YES
4220584	25400950	Sarah E. Pinder	2	were involved in the pathology review and scoring of stains for the neoductgenesis classification	were involved in the pathology review and scoring of stains for the neoductgenesis classification	Performed the experiments	Investigation	YES
4220584	25400950	Shahin Abdsaleh	2	participated in classification of the mammographic features	participated in classification of the mammographic features	-	-	NO
4220584	25400950	Tibor Tot	2	were involved in the pathology review and scoring of stains for the neoductgenesis classification	were involved in the pathology review and scoring of stains for the neoductgenesis classification	Performed the experiments	Investigation	YES
4220584	25400950	Wenjing Zhou	2	was responsible for data analyses and paper preparation and editing	was responsible for data analyses and paper preparation and editing	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
6021164	30061767	Mirhan Salibasic	7	initial phase (idea, literature review, hypothesis, execution phase, writing	initial phase (idea, literature review, hypothesis, execution phase, writing	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Formal analysis|Investigation	YES
6021164	30061767	Samir Delibegovic	7	analytical phase (analysis, final writing, revision	analytical phase (analysis, final writing, revision	Wrote the paper	Writing - Review & Editing	YES
6306938	30241307	A.F.	CRediT	Supervision	Supervision	-	Supervision	YES
6306938	30241307	A.T.-D.	CRediT	Supervision	Supervision	-	Supervision	YES
6306938	30241307	D.F.	CRediT	Conceptualization|Supervision	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6306938	30241307	D.F.	CRediT	Conceptualization|Supervision	Supervision	-	Supervision	YES
6306938	30241307	I.S.	CRediT	Supervision	Supervision	-	Supervision	YES
6306938	30241307	O.B.	CRediT	Conceptualization|Methodology	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6306938	30241307	O.B.	CRediT	Conceptualization|Methodology	Methodology	Performed the experiments	Methodology	YES
5567065	28871266	AK	2	was involved in the design of the experiment and in the critical revision of the manuscript	was involved in the design of the experiment and in the critical revision of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5567065	28871266	All authors	2	approved the final version of the manuscript	approved the final version of the manuscript	-	-	NO
5567065	28871266	CV	2	helped in experimental work and contributed to the manuscript modification	helped in experimental work and contributed to the manuscript modification	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5567065	28871266	KR	2	was involved in experimental analysis, interpretation of data and revising the manuscript	was involved in experimental analysis, interpretation of data and revising the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5567065	28871266	NS	2	was involved in experimental analysis, interpretation of data and revising the manuscript	was involved in experimental analysis, interpretation of data and revising the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5567065	28871266	PR	2	helped in experimental work and contributed to the manuscript modification	helped in experimental work and contributed to the manuscript modification	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5567065	28871266	SN	2	helped in experimental work and contributed to the manuscript modification	helped in experimental work and contributed to the manuscript modification	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5567065	28871266	SY	2	was involved in conducting the experiment, recording observations and drafting the article	was involved in conducting the experiment, recording observations and drafting the article	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5567065	28871266	US	2	helped in experimental work and contributed to the manuscript modification	helped in experimental work and contributed to the manuscript modification	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5911671	29692893	J.P.	2	supervised and brought the manuscript to its final version	supervised and brought the manuscript to its final version	-	Supervision	YES
5911671	29692893	M.K.	2	supervised and brought the manuscript to its final version	supervised and brought the manuscript to its final version	-	Supervision	YES
5911671	29692893	ZP	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5071747	27760686	RC	2	refined and redrafted for submission	refined and redrafted for submission	Wrote the paper	Writing - Original Draft	YES
5071747	27760686	SM	2	refined and redrafted for submission	refined and redrafted for submission	Wrote the paper	Writing - Original Draft	YES
4406586	25902048	GZF	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406586	25902048	GZF	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406586	25902048	GZF	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406586	25902048	GZF	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406586	25902048	MZ	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406586	25902048	MZ	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406586	25902048	TL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4406586	25902048	TL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4406586	25902048	TL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5324241	28231766	DL	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5324241	28231766	HLZ	PLoS52	performed the experiments and the analysis of small rnas associated with bmago2	performed the experiments and the analysis of small rnas associated with bmago2	Performed the experiments	Investigation	YES
5324241	28231766	QS	PLoS52	helped to analyze the data	helped to analyze the data	Analyzed the data	Formal analysis	YES
5324241	28231766	TE-sRNA	PLoS52	selection, performed the experiments, and drafted the manuscript	selection, performed the experiments, and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5324241	28231766	YJC	PLoS52	performed the experiments and the analysis of small rnas associated with bmago2	performed the experiments and the analysis of small rnas associated with bmago2	Performed the experiments	Investigation	YES
5324241	28231766	ZBL	PLoS52	helped to analyze the data	helped to analyze the data	Analyzed the data	Formal analysis	YES
5324241	28231766	ZMN	PLoS52	conceived, designed and drafted the manuscript	conceived, designed and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
6306945	30558168	C.S.H.	CRediT	Software|Validation|Formal analysis|Investigation|Resources|Data curation|Writing-review & editing|Funding acquisition	Software	Contributed reagents/materials/analysis tools	Software	YES
6306945	30558168	C.S.H.	CRediT	Software|Validation|Formal analysis|Investigation|Resources|Data curation|Writing-review & editing|Funding acquisition	Validation	Performed the experiments	Validation	YES
6306945	30558168	C.S.H.	CRediT	Software|Validation|Formal analysis|Investigation|Resources|Data curation|Writing-review & editing|Funding acquisition	Formal analysis	Analyzed the data	Formal analysis	YES
6306945	30558168	C.S.H.	CRediT	Software|Validation|Formal analysis|Investigation|Resources|Data curation|Writing-review & editing|Funding acquisition	Investigation	Performed the experiments	Investigation	YES
6306945	30558168	C.S.H.	CRediT	Software|Validation|Formal analysis|Investigation|Resources|Data curation|Writing-review & editing|Funding acquisition	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6306945	30558168	C.S.H.	CRediT	Software|Validation|Formal analysis|Investigation|Resources|Data curation|Writing-review & editing|Funding acquisition	Data curation	Analyzed the data	Data curation	YES
6306945	30558168	C.S.H.	CRediT	Software|Validation|Formal analysis|Investigation|Resources|Data curation|Writing-review & editing|Funding acquisition	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6306945	30558168	C.S.H.	CRediT	Software|Validation|Formal analysis|Investigation|Resources|Data curation|Writing-review & editing|Funding acquisition	Funding acquisition	-	Funding acquisition	YES
6306945	30558168	G.P.	CRediT	Conceptualization|Validation|Writing-review & editing|Supervision|Project administration	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6306945	30558168	G.P.	CRediT	Conceptualization|Validation|Writing-review & editing|Supervision|Project administration	Validation	Performed the experiments	Validation	YES
6306945	30558168	G.P.	CRediT	Conceptualization|Validation|Writing-review & editing|Supervision|Project administration	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6306945	30558168	G.P.	CRediT	Conceptualization|Validation|Writing-review & editing|Supervision|Project administration	Supervision	-	Supervision	YES
6306945	30558168	G.P.	CRediT	Conceptualization|Validation|Writing-review & editing|Supervision|Project administration	Project administration	-	Project administration	YES
6306945	30558168	M.R.	CRediT	Conceptualization|Methodology|Validation|Data curation|Writing-review & editing|Supervision|Project administration	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6306945	30558168	M.R.	CRediT	Conceptualization|Methodology|Validation|Data curation|Writing-review & editing|Supervision|Project administration	Methodology	Performed the experiments	Methodology	YES
6306945	30558168	M.R.	CRediT	Conceptualization|Methodology|Validation|Data curation|Writing-review & editing|Supervision|Project administration	Validation	Performed the experiments	Validation	YES
6306945	30558168	M.R.	CRediT	Conceptualization|Methodology|Validation|Data curation|Writing-review & editing|Supervision|Project administration	Data curation	Analyzed the data	Data curation	YES
6306945	30558168	M.R.	CRediT	Conceptualization|Methodology|Validation|Data curation|Writing-review & editing|Supervision|Project administration	Writing-review & editing	Wrote the paper	Writing - Review & Editing	YES
6306945	30558168	M.R.	CRediT	Conceptualization|Methodology|Validation|Data curation|Writing-review & editing|Supervision|Project administration	Supervision	-	Supervision	YES
6306945	30558168	M.R.	CRediT	Conceptualization|Methodology|Validation|Data curation|Writing-review & editing|Supervision|Project administration	Project administration	-	Project administration	YES
6306945	30558168	S.H.C.	CRediT	Writing-original draft preparation	Writing-original draft preparation	Wrote the paper	Writing - Original Draft	YES
5918165	29707208	Cabrera Yair Benjamin	7	Execution of the work. Final approval of the version to be published. 8	Execution of the work. Final approval of the version to be published. 8	Performed the experiments	Investigation	YES
5918165	29707208	Candanedo-Gonzalez Fernando	7	conception, design and execution of the work.Final approval of the version to be published. 3 Felix	conception, design and execution of the work.Final approval of the version to be published. 3 Felix	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5918165	29707208	Felix Anna Karen	7	conception, design and execution of the work. Final approval of the version to be published. 4	conception, design and execution of the work. Final approval of the version to be published. 4	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5918165	29707208	Flores-Figueroa Eugenia	7	conception, design, writing of the article and correspondent author	conception, design, writing of the article and correspondent author	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5918165	29707208	Medrano-Guzman Rafael	7	critical revision for important intellectual content. Final approval of the version to be published. 6	critical revision for important intellectual content. Final approval of the version to be published. 6	Wrote the paper	Writing - Review & Editing	YES
5918165	29707208	Quintana-Quintana Miguel	7	critical revision for important intellectual content. Final approval of the version to be published 7 Baas	critical revision for important intellectual content. Final approval of the version to be published 7 Baas	Wrote the paper	Writing - Review & Editing	YES
5918165	29707208	Sanchez-Garcia Jorge	7	conception, design and execution of the work. Final approval of the version to be published. 2	conception, design and execution of the work. Final approval of the version to be published. 2	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5918165	29707208	Sanchez-Ramirez Damian	7	Execution of the work. Final approval of the version to be published. 5	Execution of the work. Final approval of the version to be published. 5	Performed the experiments	Investigation	YES
5572150	28878793	CL	PLoS52	designed research|performed research|analyzed data|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
5572150	28878793	CL	PLoS52	designed research|performed research|analyzed data|wrote the paper	performed research	Performed the experiments	Investigation	YES
5572150	28878793	CL	PLoS52	designed research|performed research|analyzed data|wrote the paper	analyzed data	Analyzed the data	Formal analysis	YES
5572150	28878793	CL	PLoS52	designed research|performed research|analyzed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5572150	28878793	GS	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
5572150	28878793	MA	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
5572150	28878793	RY	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
5572150	28878793	RZ	PLoS52	designed research|analyzed data|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
5572150	28878793	RZ	PLoS52	designed research|analyzed data|wrote the paper	analyzed data	Analyzed the data	Formal analysis	YES
5572150	28878793	RZ	PLoS52	designed research|analyzed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5572150	28878793	SG	PLoS52	designed research|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
5572150	28878793	SG	PLoS52	designed research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5572150	28878793	SK	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
5572150	28878793	TZ	PLoS52	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5572150	28878793	WM	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5572150	28878793	YLi	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
5572150	28878793	YLiu	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
5572150	28878793	YW	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
5572150	28878793	ZM	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
5071748	27760687	GR	2	developed the main text with review and contributions from all co-authors	developed the main text with review and contributions from all co-authors	Wrote the paper	Writing - Review & Editing	YES
5071748	27760687	The authors	2	jointly conceived the structure and content of the article	jointly conceived the structure and content of the article	Conceived and designed the experiments	Conceptualization	YES
4406587	25901755	JK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406587	25901755	JK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406587	25901755	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406587	25901755	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406587	25901755	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406587	25901755	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406587	25901755	KK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4406587	25901755	MMJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406587	25901755	MMJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406587	25901755	MMJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406587	25901755	MMJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406587	25901755	PM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4406587	25901755	PM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406587	25901755	RT	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3655683	23737723	Shuyu Fang	2	contributed equally to this work	contributed equally to this work	-	-	NO
3655683	23737723	Yanhua Wu	2	contributed equally to this work	contributed equally to this work	-	-	NO
5938242	29744047	Azim Mirzazadeh	7	study design	study design	Conceived and designed the experiments	Methodology	YES
5938242	29744047	Javad Tavakkoly Bazzaz	7	data gathering	data gathering	-	-	NO
5938242	29744047	Mahboobeh Khabaz Mafinejad	7	study design, data gathering and analysis, writing and revising the manuscript	study design, data gathering and analysis, writing and revising the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5938242	29744047	Maliheh Kadivar	7	idea generation, study design, data gathering, revising the manuscript	idea generation, study design, data gathering, revising the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Writing - Review & Editing	YES
5938242	29744047	Zeinab Jannat	7	data gathering	data gathering	-	-	NO
3457591	23019521	All authors	2	were involved in data collection, revised the final draft, and gave approval for submission	were involved in data collection, revised the final draft, and gave approval for submission	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
3457591	23019521	D. Ogoina	2	conceived the report and wrote the paper	conceived the report and wrote the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
6194931	30514989	Each author	2	participated in each step of research|gave final approval for final version of article	participated in each step of research	-	-	NO
6194931	30514989	Each author	2	participated in each step of research|gave final approval for final version of article	gave final approval for final version of article	-	-	NO
6194931	30514989	G.R.	2	revised it critically	revised it critically	Wrote the paper	Writing - Review & Editing	YES
5071749	27760689	Gus Cairns	2	have produced this article in close collaboration and both have contributed equally to the final version of the text	have produced this article in close collaboration and both have contributed equally to the final version of the text	Wrote the paper	Writing - Original Draft	YES
5071749	27760689	Kane Race	2	have produced this article in close collaboration and both have contributed equally to the final version of the text	have produced this article in close collaboration and both have contributed equally to the final version of the text	Wrote the paper	Writing - Original Draft	YES
5071749	27760689	Pedro Goicochea	2	contributed in the synthesis of the main ideas to produce a more succinct version of the article	contributed in the synthesis of the main ideas to produce a more succinct version of the article	Conceived and designed the experiments	Conceptualization	YES
4406590	25901348	ELG	PLoS5	Input on the study design and analysis	Input on the study design and analysis	Conceived and designed the experiments	Methodology	YES
4406590	25901348	FRA	PLoS5	Wrote the paper|Input on the study design and analysis	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406590	25901348	FRA	PLoS5	Wrote the paper|Input on the study design and analysis	Input on the study design and analysis	Conceived and designed the experiments	Methodology	YES
4406590	25901348	JRB	PLoS5	Input on the study design and analysis	Input on the study design and analysis	Conceived and designed the experiments	Methodology	YES
4406590	25901348	LMLM	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4406590	25901348	PGC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406590	25901348	PGC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406590	25901348	PGC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406590	25901348	RFPT	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4406590	25901348	TBC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406590	25901348	TBC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406590	25901348	TBC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406590	25901348	TBC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5572210	28878800	CF	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5572210	28878800	KD	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
5572210	28878800	KD	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5572210	28878800	LY	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5572210	28878800	MZ	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5572210	28878800	SZ	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
5572210	28878800	SZ	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5572210	28878800	WL	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5572210	28878800	WL	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
5572210	28878800	WL	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5572210	28878800	YC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5938244	29744050	All the authors	2	contributed on the realization of the manuscript	contributed on the realization of the manuscript	-	-	NO
3463159	23050130	A. A. Akinbami	PLoS52	recruited the patients and collected data	recruited the patients and collected data	Performed the experiments	Investigation	YES
3463159	23050130	A. M. Danesi	PLoS52	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
3463159	23050130	F. I. Ojini	PLoS52	reviewed the paper for intellectual content and approved the final version	reviewed the paper for intellectual content and approved the final version	Wrote the paper	Writing - Review & Editing	YES
3463159	23050130	O. O. Ojo	PLoS52	recruited the patients and collected data	recruited the patients and collected data	Performed the experiments	Investigation	YES
3463159	23050130	O. O. Oshinaike	PLoS52	designed the study|recruited the patients and collected data|analyzed the data	designed the study	Conceived and designed the experiments	Methodology	YES
3463159	23050130	O. O. Oshinaike	PLoS52	designed the study|recruited the patients and collected data|analyzed the data	recruited the patients and collected data	Performed the experiments	Investigation	YES
3463159	23050130	O. O. Oshinaike	PLoS52	designed the study|recruited the patients and collected data|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
3463159	23050130	U. N. Okubadejo	PLoS52	analyzed the data|reviewed the paper for intellectual content and approved the final version	analyzed the data	Analyzed the data	Formal analysis	YES
3463159	23050130	U. N. Okubadejo	PLoS52	analyzed the data|reviewed the paper for intellectual content and approved the final version	reviewed the paper for intellectual content and approved the final version	Wrote the paper	Writing - Review & Editing	YES
6194947	30515000	All authors	2	were included in all steps of preparations of this case report	were included in all steps of preparations of this case report	-	-	NO
4406591	25901363	HK	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406591	25901363	HK	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406591	25901363	HK	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406591	25901363	JZ	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406591	25901363	JZ	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406591	25901363	LA	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406591	25901363	LB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406591	25901363	LB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406591	25901363	LB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406591	25901363	LX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406591	25901363	LX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406591	25901363	LX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406591	25901363	LX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406591	25901363	LX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406591	25901363	MB	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406591	25901363	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406591	25901363	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406591	25901363	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406591	25901363	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406591	25901363	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406591	25901363	QH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406591	25901363	QH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406591	25901363	QH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406591	25901363	RM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406591	25901363	RM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406591	25901363	RM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406591	25901363	RM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406591	25901363	SK	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406591	25901363	SK	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4503556	26229957	All authors	2	have read and approved the final version of this paper	have read and approved the final version of this paper	-	-	NO
4503556	26229957	Ashwin Belle	2	contributed equally to this work	contributed equally to this work	-	-	NO
4503556	26229957	Daniel A. Beard	2	contributed to and supervised the whole paper	contributed to and supervised the whole paper	-	Supervision	YES
4503556	26229957	Fatemeh Navidi	2	contributed to the section on image processing	contributed to the section on image processing	Analyzed the data	Visualization	YES
4503556	26229957	Kayvan Najarian	2	contributed to and supervised the whole paper	contributed to and supervised the whole paper	-	Supervision	YES
4503556	26229957	Raghuram Thiagarajan	2	contributed equally to this work	contributed equally to this work	-	-	NO
4503556	26229957	S. M. Reza	2	is the primary author for the image processing section and contributed to the whole paper|contributed equally to this work	is the primary author for the image processing section and contributed to the whole paper	Analyzed the data|Wrote the paper	Visualization|Writing - Original Draft	YES
4503556	26229957	S. M. Reza	2	is the primary author for the image processing section and contributed to the whole paper|contributed equally to this work	contributed equally to this work	-	-	NO
5938245	29744046	Elhamsadat Banimostafavi	7	data collection, imaging report	data collection, imaging report	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
5938245	29744046	Maryam Tayebi	7	writing the paper	writing the paper	Wrote the paper	Writing - Original Draft	YES
6194948	30514998	All authors	2	equally participated in preparing this case report presentation	equally participated in preparing this case report presentation	-	-	NO
5071750	27760683	JMS	2	reviewed the literature and wrote the manuscript	reviewed the literature and wrote the manuscript	Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5071750	27760683	MBD	2	reviewed the literature and wrote the manuscript	reviewed the literature and wrote the manuscript	Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5071750	27760683	RG	2	reviewed the literature and wrote the manuscript	reviewed the literature and wrote the manuscript	Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5327517	28241792	JR	2	clustered protein families into orthologous groups	clustered protein families into orthologous groups	Performed the experiments	Investigation	YES
5327517	28241792	RS	2	conducted ancestral reconstruction and identified gain/loss families	conducted ancestral reconstruction and identified gain/loss families	Performed the experiments	Investigation	YES
5327517	28241792	SO	2	carried out electronic annotation and enrichment analyses	carried out electronic annotation and enrichment analyses	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
3463904	23056931	A. A. Akinbami	2	conceptualized, designed, and did data entry and analysis of the study	conceptualized, designed, and did data entry and analysis of the study	Conceived and designed the experiments|Analyzed the data	Conceptualization|Data curation|Formal analysis|Methodology	YES
3463904	23056931	A. Adediran	2	made substantial contributions to conception and design of the paper and reviewed it before final submission	made substantial contributions to conception and design of the paper and reviewed it before final submission	Conceived and designed the experiments	Conceptualization	YES
3463904	23056931	A. O. Dosunmu	2	drafted the paper and revised it critically for important intellectual content	drafted the paper and revised it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3463904	23056931	K. O. Wright	2	was involved in the drafting of the paper and reviewed it critically for important intellectual content	was involved in the drafting of the paper and reviewed it critically for important intellectual content	Wrote the paper	Writing - Original Draft	YES
3463904	23056931	O. Arogundade	2	carried out the cd4 count assay	carried out the cd4 count assay	Performed the experiments	Investigation	YES
3463904	23056931	O. Oshinaike	2	reviewed paper before final submission	reviewed paper before final submission	Wrote the paper	Writing - Review & Editing	YES
3463904	23056931	S. O. Ajibola	2	reviewed the paper critically for important intellectual content and gave final approval of the version to be published	reviewed the paper critically for important intellectual content and gave final approval of the version to be published	Wrote the paper	Writing - Review & Editing	YES
6194949	30514991	All authors	2	were included in all steps of preparation this article|provided critical feedback and helped shape the manuscript	were included in all steps of preparation this article	-	-	NO
6194949	30514991	All authors	2	were included in all steps of preparation this article|provided critical feedback and helped shape the manuscript	provided critical feedback and helped shape the manuscript	-	-	NO
6194949	30514991	Enra Mehmedika Suljic	2	contributed to the interpretation of the results, supervised the project and gave a final approval	contributed to the interpretation of the results, supervised the project and gave a final approval	Analyzed the data	Formal analysis|Supervision	YES
5938246	29744051	AF	7	Concept and study design, approval of final manuscript	Concept and study design, approval of final manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
5938246	29744051	AW	7	Data collection and analysis, editing of manuscript, approval of final manuscript	Data collection and analysis, editing of manuscript, approval of final manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
5938246	29744051	BG	7	Data collection and analysis, editing of manuscript, approval of final manuscript	Data collection and analysis, editing of manuscript, approval of final manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
5938246	29744051	CC	7	Concept and study design, drafting of manuscript, approval of final manuscript	Concept and study design, drafting of manuscript, approval of final manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5938246	29744051	CL	7	Data collection and analysis, editing of manuscript, approval of final manuscript	Data collection and analysis, editing of manuscript, approval of final manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
5938246	29744051	KK	7	Data collection and analysis, editing of manuscript, approval of final manuscript	Data collection and analysis, editing of manuscript, approval of final manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
5938246	29744051	RAA	7	Concept and study design, approval of final manuscript	Concept and study design, approval of final manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
5938246	29744051	RT	7	Data collection and analysis, editing of manuscript, approval of final manuscript	Data collection and analysis, editing of manuscript, approval of final manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
5938246	29744051	TEP	7	Concept and study design, revisions, drafting of final manuscript, approval of final manuscript	Concept and study design, revisions, drafting of final manuscript, approval of final manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5938246	29744051	YAO	7	Data collection and analysis, editing of manuscript, approval of final manuscript	Data collection and analysis, editing of manuscript, approval of final manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
4406594	25901912	DV	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406594	25901912	DV	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406594	25901912	DV	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406594	25901912	LH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406594	25901912	LH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406594	25901912	LH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406594	25901912	LKB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4406594	25901912	MP	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406594	25901912	MP	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5071751	27760681	J-MM	2	commented and expanded	commented and expanded	-	-	NO
5071751	27760681	SMC	2	created the final draft and submitted the manuscript	created the final draft and submitted the manuscript	Wrote the paper	Writing - Original Draft	YES
5071751	27760681	VN	2	commented and expanded	commented and expanded	-	-	NO
5572244	28878792	PB	2	collected and analyzed the data|designed the studies and all were involved in securing funding for the research	collected and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5572244	28878792	PB	2	collected and analyzed the data|designed the studies and all were involved in securing funding for the research	designed the studies and all were involved in securing funding for the research	Conceived and designed the experiments	Funding acquisition|Methodology	YES
5572244	28878792	RR	2	collected and analyzed the data|designed the studies and all were involved in securing funding for the research|died before the final draft of the manuscript was completed but he assisted with the preparation of early drafts	collected and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5572244	28878792	RR	2	collected and analyzed the data|designed the studies and all were involved in securing funding for the research|died before the final draft of the manuscript was completed but he assisted with the preparation of early drafts	designed the studies and all were involved in securing funding for the research	Conceived and designed the experiments	Funding acquisition|Methodology	YES
5572244	28878792	RR	2	collected and analyzed the data|designed the studies and all were involved in securing funding for the research|died before the final draft of the manuscript was completed but he assisted with the preparation of early drafts	died before the final draft of the manuscript was completed but he assisted with the preparation of early drafts	Wrote the paper	Writing - Original Draft	YES
5572244	28878792	SF	2	designed the studies and all were involved in securing funding for the research	designed the studies and all were involved in securing funding for the research	Conceived and designed the experiments	Funding acquisition|Methodology	YES
5327544	28241862	AKC	PLoS52	performed physiological and biochemical experiments|performed physiological data analysis	performed physiological and biochemical experiments	Performed the experiments	Investigation	YES
5327544	28241862	AKC	PLoS52	performed physiological and biochemical experiments|performed physiological data analysis	performed physiological data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5327544	28241862	CKS	PLoS52	performed molecular experiments and analysis of molecular data|performed physiological and biochemical experiments|wrote the manuscript	performed molecular experiments and analysis of molecular data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5327544	28241862	CKS	PLoS52	performed molecular experiments and analysis of molecular data|performed physiological and biochemical experiments|wrote the manuscript	performed physiological and biochemical experiments	Performed the experiments	Investigation	YES
5327544	28241862	CKS	PLoS52	performed molecular experiments and analysis of molecular data|performed physiological and biochemical experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5327544	28241862	DS	PLoS52	conceived and designed the experiments|wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5327544	28241862	DS	PLoS52	conceived and designed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5327544	28241862	JT	PLoS52	performed molecular experiments and analysis of molecular data|wrote the manuscript	performed molecular experiments and analysis of molecular data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5327544	28241862	JT	PLoS52	performed molecular experiments and analysis of molecular data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5327544	28241862	KG	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5327544	28241862	MP	PLoS52	conceived and designed the experiments|wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5327544	28241862	MP	PLoS52	conceived and designed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5327544	28241862	RSST	PLoS52	performed molecular experiments and analysis of molecular data	performed molecular experiments and analysis of molecular data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5071752	27760682	All authors	2	reviewed and approved the final version	reviewed and approved the final version	-	-	NO
5071752	27760682	JBM	2	conceived the study|developed the methods|did the analyses and wrote the paper	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5071752	27760682	JBM	2	conceived the study|developed the methods|did the analyses and wrote the paper	developed the methods	Performed the experiments	Methodology	YES
5071752	27760682	JBM	2	conceived the study|developed the methods|did the analyses and wrote the paper	did the analyses and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5071752	27760682	S-JA	2	developed the methods	developed the methods	Performed the experiments	Methodology	YES
5071752	27760682	TBH	2	conceived the study|developed the methods	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5071752	27760682	TBH	2	conceived the study|developed the methods	developed the methods	Performed the experiments	Methodology	YES
6194966	30514990	A.D.N.	2	revised it critically	revised it critically	Wrote the paper	Writing - Review & Editing	YES
6194966	30514990	Each author	2	participated in each step of research|gave final approval for final version of article	participated in each step of research	-	-	NO
6194966	30514990	Each author	2	participated in each step of research|gave final approval for final version of article	gave final approval for final version of article	-	-	NO
5938417	29744045	Gebreyohans Gebru	PLoS52	wrote the paper|reviewed the paper and approved for publication	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5938417	29744045	Gebreyohans Gebru	PLoS52	wrote the paper|reviewed the paper and approved for publication	reviewed the paper and approved for publication	Wrote the paper	Writing - Review & Editing	YES
5938417	29744045	Mesfin Demeke	PLoS52	has developed the concept of the study, identified the case and conceived to convert it into scientific article|reviewed the paper and approved for publication	has developed the concept of the study, identified the case and conceived to convert it into scientific article	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
5938417	29744045	Mesfin Demeke	PLoS52	has developed the concept of the study, identified the case and conceived to convert it into scientific article|reviewed the paper and approved for publication	reviewed the paper and approved for publication	Wrote the paper	Writing - Review & Editing	YES
5071753	27760690	CFC	2	wrote the first draft of this editorial and produced the final version based on comments from co-editors	wrote the first draft of this editorial and produced the final version based on comments from co-editors	Wrote the paper	Writing - Original Draft	YES
4406608	25902064	DB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406608	25902064	DB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406608	25902064	DB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406608	25902064	LBW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406608	25902064	LBW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406608	25902064	LBW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406608	25902064	LBW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406608	25902064	LT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406608	25902064	LT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406608	25902064	LT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406608	25902064	LT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406608	25902064	TGK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406608	25902064	TGK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406608	25902064	TGK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6194967	30514992	all authors	2	were included to all phases of preparation this article	were included to all phases of preparation this article	-	-	NO
5572249	28878784	All authors	PLoS52	approved the manuscript	approved the manuscript	-	-	NO
5572249	28878784	FL	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5572249	28878784	FR	PLoS52	conceived the experiments|performed gwa analyses|wrote and corrected the manuscript	conceived the experiments	Conceived and designed the experiments	Conceptualization	YES
5572249	28878784	FR	PLoS52	conceived the experiments|performed gwa analyses|wrote and corrected the manuscript	performed gwa analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5572249	28878784	FR	PLoS52	conceived the experiments|performed gwa analyses|wrote and corrected the manuscript	wrote and corrected the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5572249	28878784	FV	PLoS52	conceived the experiments|performed the experiments|analyzed the other data|wrote and corrected the manuscript	conceived the experiments	Conceived and designed the experiments	Conceptualization	YES
5572249	28878784	FV	PLoS52	conceived the experiments|performed the experiments|analyzed the other data|wrote and corrected the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5572249	28878784	FV	PLoS52	conceived the experiments|performed the experiments|analyzed the other data|wrote and corrected the manuscript	analyzed the other data	Analyzed the data	Formal analysis	YES
5572249	28878784	FV	PLoS52	conceived the experiments|performed the experiments|analyzed the other data|wrote and corrected the manuscript	wrote and corrected the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5572249	28878784	LD	PLoS52	wrote and corrected the manuscript	wrote and corrected the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5572249	28878784	LT	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5572249	28878784	NA	PLoS52	conceived the experiments|performed the experiments|performed gwa analyses|analyzed the other data|wrote and corrected the manuscript	conceived the experiments	Conceived and designed the experiments	Conceptualization	YES
5572249	28878784	NA	PLoS52	conceived the experiments|performed the experiments|performed gwa analyses|analyzed the other data|wrote and corrected the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5572249	28878784	NA	PLoS52	conceived the experiments|performed the experiments|performed gwa analyses|analyzed the other data|wrote and corrected the manuscript	performed gwa analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5572249	28878784	NA	PLoS52	conceived the experiments|performed the experiments|performed gwa analyses|analyzed the other data|wrote and corrected the manuscript	analyzed the other data	Analyzed the data	Formal analysis	YES
5572249	28878784	NA	PLoS52	conceived the experiments|performed the experiments|performed gwa analyses|analyzed the other data|wrote and corrected the manuscript	wrote and corrected the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5572249	28878784	RB	PLoS52	conceived the experiments|performed the experiments|analyzed the other data|wrote and corrected the manuscript	conceived the experiments	Conceived and designed the experiments	Conceptualization	YES
5572249	28878784	RB	PLoS52	conceived the experiments|performed the experiments|analyzed the other data|wrote and corrected the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5572249	28878784	RB	PLoS52	conceived the experiments|performed the experiments|analyzed the other data|wrote and corrected the manuscript	analyzed the other data	Analyzed the data	Formal analysis	YES
5572249	28878784	RB	PLoS52	conceived the experiments|performed the experiments|analyzed the other data|wrote and corrected the manuscript	wrote and corrected the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5327563	28241794	CL	2	pipeline, snps and comparative genome analyses, database queries, 3d modelling, data interpretation and drafting of the paper	pipeline, snps and comparative genome analyses, database queries, 3d modelling, data interpretation and drafting of the paper	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Software|Writing - Original Draft	YES
5327563	28241794	FC	2	drug target analysis and data interpretation	drug target analysis and data interpretation	Analyzed the data	Formal analysis	YES
5327563	28241794	FMGA	2	acms library construction and keeg analysis	acms library construction and keeg analysis	Performed the experiments	Investigation	YES
5327563	28241794	GO	2	design and concept of the study, and writing of the final manuscript	design and concept of the study, and writing of the final manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5327563	28241794	JA	2	acms library construction and keeg analysis	acms library construction and keeg analysis	Performed the experiments	Investigation	YES
5327563	28241794	LK	2	design and concept of the study, and writing of the final manuscript	design and concept of the study, and writing of the final manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5327563	28241794	LLM	2	design and concept of the study, and writing of the final manuscript	design and concept of the study, and writing of the final manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5327563	28241794	MC	2	drug target analysis and data interpretation	drug target analysis and data interpretation	Analyzed the data	Formal analysis	YES
5327563	28241794	MR	2	design and concept of the study, and writing of the final manuscript	design and concept of the study, and writing of the final manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5327563	28241794	NM	2	drug target analysis and data interpretation	drug target analysis and data interpretation	Analyzed the data	Formal analysis	YES
5327563	28241794	OtrhoM	2	pipeline, snps and comparative genome analyses, database queries, 3d modelling, data interpretation and drafting of the paper	pipeline, snps and comparative genome analyses, database queries, 3d modelling, data interpretation and drafting of the paper	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Software|Writing - Original Draft	YES
5327563	28241794	RNA	2	pathway analysis	pathway analysis	-	-	NO
5938418	29744048	HU	2	contributed to the conception and design|did the data collection|did the writing of the article and the critical revisions	contributed to the conception and design	Conceived and designed the experiments	Conceptualization	YES
5938418	29744048	HU	2	contributed to the conception and design|did the data collection|did the writing of the article and the critical revisions	did the data collection	Performed the experiments	Investigation	YES
5938418	29744048	HU	2	contributed to the conception and design|did the data collection|did the writing of the article and the critical revisions	did the writing of the article and the critical revisions	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5938418	29744048	NM	2	did the data collection|did the analysis and interpretation	did the data collection	Performed the experiments	Investigation	YES
5938418	29744048	NM	2	did the data collection|did the analysis and interpretation	did the analysis and interpretation	Analyzed the data	Formal analysis	YES
5071778	27760684	All authors	2	contributed to the writing and editing of this manuscript	contributed to the writing and editing of this manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5938524	29744049	MP	2	wrote this article together	wrote this article together	Wrote the paper	Writing - Original Draft	YES
5938524	29744049	NS	2	wrote this article together	wrote this article together	Wrote the paper	Writing - Original Draft	YES
5938524	29744049	ZA	2	wrote this article together	wrote this article together	Wrote the paper	Writing - Original Draft	YES
5938524	29744049	ZH	2	wrote this article together	wrote this article together	Wrote the paper	Writing - Original Draft	YES
6195014	30514999	A.A.	2	reviewing the writing of the case report and all information of the patient	reviewing the writing of the case report and all information of the patient	Wrote the paper	-	YES
6195014	30514999	A.A.A.	2	following the patient up and wring the case report	following the patient up and wring the case report	-	-	NO
6195014	30514999	H.A.A.	2	reviewing the writing of the case report and all information of the patient	reviewing the writing of the case report and all information of the patient	Wrote the paper	-	YES
6195014	30514999	OR	2	following the patient up and wring the case report	following the patient up and wring the case report	-	-	NO
4894854	27271304	Both authors	2	participated equally in performing the review and writing the manuscript	participated equally in performing the review and writing the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
4406609	25901577	CZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406609	25901577	CZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406609	25901577	CZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406609	25901577	CZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406609	25901577	JS	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4406609	25901577	LZ	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406609	25901577	LZ	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406609	25901577	SJ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4406609	25901577	YL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4406609	25901577	YL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406609	25901577	YW	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4406609	25901577	YW	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406609	25901577	YZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4406609	25901577	ZD	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406609	25901577	ZD	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406609	25901577	ZD	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6195015	30514997	The authors	2	contributed equally to this review|read and approved the final version of the manuscript	contributed equally to this review	-	-	NO
6195015	30514997	The authors	2	contributed equally to this review|read and approved the final version of the manuscript	read and approved the final version of the manuscript	-	-	NO
5329932	28241790	CL	2	helped to conceive and design the experiments and did the sampling	helped to conceive and design the experiments and did the sampling	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
5329932	28241790	JC	2	did the sampling, conducted the experiments, analyzed the data and wrote the manuscript|helped to conceive and design the experiments	did the sampling, conducted the experiments, analyzed the data and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5329932	28241790	JC	2	did the sampling, conducted the experiments, analyzed the data and wrote the manuscript|helped to conceive and design the experiments	helped to conceive and design the experiments	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
5329932	28241790	JR	2	conceived and designed the experiments, did the sampling, analyzed the data and wrote the manuscript	conceived and designed the experiments, did the sampling, analyzed the data and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5329932	28241790	SD	2	helped to conceive and design the experiments and did the sampling	helped to conceive and design the experiments and did the sampling	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
5329932	28241790	XH	2	did the sampling and conducted the experiments	did the sampling and conducted the experiments	Performed the experiments	Investigation	YES
5329932	28241790	XY	2	did the sampling, conducted the experiments and analyzed the data	did the sampling, conducted the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
1523356	16808848	AK	2	was responsible for all aspects of this project including curriculum development, course instruction, development of the assessment tool, conduction of resident survey, data interpretation, and manuscript authorship	was responsible for all aspects of this project including curriculum development, course instruction, development of the assessment tool, conduction of resident survey, data interpretation, and manuscript authorship	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Supervision|Writing - Original Draft	YES
5071779	27760685	AB	2	proposed text and references for specific sections and general suggestions for the full text	proposed text and references for specific sections and general suggestions for the full text	Conceived and designed the experiments	Conceptualization	YES
5071779	27760685	CB	2	provided suggestions for specific topics	provided suggestions for specific topics	-	-	NO
5071779	27760685	CFC	2	wrote the first draft and managed the subsequent versions	wrote the first draft and managed the subsequent versions	Wrote the paper	Writing - Original Draft	YES
5071779	27760685	JDK	2	provided suggestions for specific topics	provided suggestions for specific topics	-	-	NO
5071779	27760685	RB	2	proposed text and references for specific sections and general suggestions for the full text	proposed text and references for specific sections and general suggestions for the full text	Conceived and designed the experiments	Conceptualization	YES
5938526	29744052	Jianping Gong	7	Correspondence author& revision	Correspondence author& revision	Wrote the paper	Writing - Review & Editing	YES
5938526	29744052	Peng Yu	7	data collections & data analysis& writing	data collections & data analysis& writing	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation	YES
5572255	28878785	All of the authors	2	proof-read the manuscript and approve for publication	proof-read the manuscript and approve for publication	-	-	NO
5572255	28878785	FA	2	conducted research under the supervision of ma and write up initial draft of manuscript|carried out statistical analysis and interpretation of data	conducted research under the supervision of ma and write up initial draft of manuscript	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Original Draft	YES
5572255	28878785	FA	2	conducted research under the supervision of ma and write up initial draft of manuscript|carried out statistical analysis and interpretation of data	carried out statistical analysis and interpretation of data	Analyzed the data	Formal analysis	YES
5572255	28878785	NK	2	carried out statistical analysis and interpretation of data|make corrections in the final manuscript and edited for final version	carried out statistical analysis and interpretation of data	Analyzed the data	Formal analysis	YES
5572255	28878785	NK	2	carried out statistical analysis and interpretation of data|make corrections in the final manuscript and edited for final version	make corrections in the final manuscript and edited for final version	Wrote the paper	Writing - Review & Editing	YES
5572255	28878785	QA	2	carried out statistical analysis and interpretation of data	carried out statistical analysis and interpretation of data	Analyzed the data	Formal analysis	YES
6195016	30514987	AT	7	Contributed to conception and design|Acquisition of data|Analysis and interpretation of data	Contributed to conception and design	Conceived and designed the experiments	Conceptualization	YES
6195016	30514987	AT	7	Contributed to conception and design|Acquisition of data|Analysis and interpretation of data	Acquisition of data	Performed the experiments	Investigation	YES
6195016	30514987	AT	7	Contributed to conception and design|Acquisition of data|Analysis and interpretation of data	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
6195016	30514987	ML	7	Contributed to conception and design	Contributed to conception and design	Conceived and designed the experiments	Conceptualization	YES
6195016	30514987	MT	7	Contributed to conception and design|Drafting the article and revising it for intellectual content|Final approval of the version to be published made by the first author	Contributed to conception and design	Conceived and designed the experiments	Conceptualization	YES
6195016	30514987	MT	7	Contributed to conception and design|Drafting the article and revising it for intellectual content|Final approval of the version to be published made by the first author	Drafting the article and revising it for intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6195016	30514987	MT	7	Contributed to conception and design|Drafting the article and revising it for intellectual content|Final approval of the version to be published made by the first author	Final approval of the version to be published made by the first author	-	-	NO
6195016	30514987	PT	7	Contributed to conception and design|Final approval of the version to be published made by the first author	Contributed to conception and design	Conceived and designed the experiments	Conceptualization	YES
6195016	30514987	PT	7	Contributed to conception and design|Final approval of the version to be published made by the first author	Final approval of the version to be published made by the first author	-	-	NO
6195016	30514987	SZ	7	Contributed to conception and design|Final approval of the version to be published made by the first author	Contributed to conception and design	Conceived and designed the experiments	Conceptualization	YES
6195016	30514987	SZ	7	Contributed to conception and design|Final approval of the version to be published made by the first author	Final approval of the version to be published made by the first author	-	-	NO
6195016	30514987	VA	7	Contributed to conception and design|Acquisition of data|Analysis and interpretation of data|Drafting the article and revising it for intellectual content	Contributed to conception and design	Conceived and designed the experiments	Conceptualization	YES
6195016	30514987	VA	7	Contributed to conception and design|Acquisition of data|Analysis and interpretation of data|Drafting the article and revising it for intellectual content	Acquisition of data	Performed the experiments	Investigation	YES
6195016	30514987	VA	7	Contributed to conception and design|Acquisition of data|Analysis and interpretation of data|Drafting the article and revising it for intellectual content	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
6195016	30514987	VA	7	Contributed to conception and design|Acquisition of data|Analysis and interpretation of data|Drafting the article and revising it for intellectual content	Drafting the article and revising it for intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5991894	29892336	Hironori Ohdaira	2	participated in its design and helped to draft the manuscript	participated in its design and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
5991894	29892336	Masaki Kitajima	2	designed this study	designed this study	Conceived and designed the experiments	Methodology	YES
5991894	29892336	Masashi Yoshida	2	participated in its design and helped to draft the manuscript	participated in its design and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
5991894	29892336	Yuichi Nakaseko	2	collected the data and drafted the manuscript	collected the data and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5991894	29892336	Yutaka Suzuki	2	designed this study	designed this study	Conceived and designed the experiments	Methodology	YES
4406610	25901750	MCM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406610	25901750	MCM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406610	25901750	MCM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406610	25901750	SAC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406610	25901750	SAC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406610	25901750	SAC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406610	25901750	SAC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1524970	16800884	DBR	2	each participated in the conception and design of the research and the drafting and editing of the manuscript|have both read and approved the final version of the manuscript	each participated in the conception and design of the research and the drafting and editing of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
1524970	16800884	DBR	2	each participated in the conception and design of the research and the drafting and editing of the manuscript|have both read and approved the final version of the manuscript	have both read and approved the final version of the manuscript	-	-	NO
1524970	16800884	DBV	2	each participated in the conception and design of the research and the drafting and editing of the manuscript|have both read and approved the final version of the manuscript	each participated in the conception and design of the research and the drafting and editing of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
1524970	16800884	DBV	2	each participated in the conception and design of the research and the drafting and editing of the manuscript|have both read and approved the final version of the manuscript	have both read and approved the final version of the manuscript	-	-	NO
5330121	28241738	GQS	PLoS52	conceived and supervised this study|analysed the data|performed the experiments|interpreted the results and wrote the manuscript	conceived and supervised this study	Conceived and designed the experiments	Conceptualization|Supervision	YES
5330121	28241738	GQS	PLoS52	conceived and supervised this study|analysed the data|performed the experiments|interpreted the results and wrote the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
5330121	28241738	GQS	PLoS52	conceived and supervised this study|analysed the data|performed the experiments|interpreted the results and wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5330121	28241738	GQS	PLoS52	conceived and supervised this study|analysed the data|performed the experiments|interpreted the results and wrote the manuscript	interpreted the results and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5330121	28241738	GYL	PLoS52	conceived and supervised this study|interpreted the results and wrote the manuscript	conceived and supervised this study	Conceived and designed the experiments	Conceptualization|Supervision	YES
5330121	28241738	GYL	PLoS52	conceived and supervised this study|interpreted the results and wrote the manuscript	interpreted the results and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5330121	28241738	JG	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5330121	28241738	JW	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5330121	28241738	MLC	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5330121	28241738	RZZ	PLoS52	analysed the data|interpreted the results and wrote the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
5330121	28241738	RZZ	PLoS52	analysed the data|interpreted the results and wrote the manuscript	interpreted the results and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5330121	28241738	SJZ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5330121	28241738	WL	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5330121	28241738	XDH	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5330121	28241738	YLL	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
4417987	25973277	Dongquan Chen	2	contributed equally to the study	contributed equally to the study	-	-	NO
4417987	25973277	Yufeng Li	2	contributed equally to the study	contributed equally to the study	-	-	NO
6195019	30514996	all authors	2	equally participated in preparing this case report	equally participated in preparing this case report	-	-	NO
6004734	29922464	David Eugenio Hinojosa	7	He is a senior year medical student. He recollected the patient data, and wrote the presentation of the case	He is a senior year medical student. He recollected the patient data, and wrote the presentation of the case	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6004734	29922464	Enrique Quevedo-Fernandez	7	He is a first year surgical resident. He helped recollected the patient data, and helped wrote the manuscript	He is a first year surgical resident. He helped recollected the patient data, and helped wrote the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6004734	29922464	Mauricio Gonzalez- Urquijo	7	He is a second year general surgery resident. He was the leader of the work, he design the case report. He recollected data, and wrote the manuscript	He is a second year general surgery resident. He was the leader of the work, he design the case report. He recollected data, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Original Draft	YES
5572256	28878786	CWL	2	performed experiments and analyzed the results	performed experiments and analyzed the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5572256	28878786	EH	2	performed experiments and analyzed the results	performed experiments and analyzed the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5572256	28878786	S-WH	2	designed the experiments and wrote the manuscript	designed the experiments and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5572256	28878786	SCL	2	designed the experiments and wrote the manuscript	designed the experiments and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4406611	25901570	JT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406611	25901570	JT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406611	25901570	JT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406611	25901570	JT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406611	25901570	NH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406611	25901570	NH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406611	25901570	SG-S	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406611	25901570	SG-S	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4406611	25901570	SG-S	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406611	25901570	WNC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406611	25901570	WNC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406611	25901570	WNC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406611	25901570	WNC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406611	25901570	YHY	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4406611	25901570	YHY	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406611	25901570	YWC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1693913	17144913	AP	2	have all participated in the design and the writing of the manuscript, as well as the editing of the final draft	have all participated in the design and the writing of the manuscript, as well as the editing of the final draft	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
1693913	17144913	DH	2	have all participated in the design and the writing of the manuscript, as well as the editing of the final draft	have all participated in the design and the writing of the manuscript, as well as the editing of the final draft	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
1693913	17144913	MS	2	have all participated in the design and the writing of the manuscript, as well as the editing of the final draft	have all participated in the design and the writing of the manuscript, as well as the editing of the final draft	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5073219	27765142	BDN	2	had full access to all of the data in the analysis and take responsibility for the integrity of the data and the accuracy of the data analysis	had full access to all of the data in the analysis and take responsibility for the integrity of the data and the accuracy of the data analysis	Analyzed the data	Data curation|Formal analysis	YES
5073219	27765142	JPM	2	contributed to the interpretation of the data, preparation and writing of the manuscript	contributed to the interpretation of the data, preparation and writing of the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
5073219	27765142	LST	2	had full access to all of the data in the analysis and take responsibility for the integrity of the data and the accuracy of the data analysis|contributed to the design of the analysis|contributed to the interpretation of the data, preparation and writing of the manuscript	had full access to all of the data in the analysis and take responsibility for the integrity of the data and the accuracy of the data analysis	Analyzed the data	Data curation|Formal analysis	YES
5073219	27765142	LST	2	had full access to all of the data in the analysis and take responsibility for the integrity of the data and the accuracy of the data analysis|contributed to the design of the analysis|contributed to the interpretation of the data, preparation and writing of the manuscript	contributed to the design of the analysis	Conceived and designed the experiments	-	YES
5073219	27765142	LST	2	had full access to all of the data in the analysis and take responsibility for the integrity of the data and the accuracy of the data analysis|contributed to the design of the analysis|contributed to the interpretation of the data, preparation and writing of the manuscript	contributed to the interpretation of the data, preparation and writing of the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
5073219	27765142	SS	2	contributed to the design of the analysis|contributed to the interpretation of the data, preparation and writing of the manuscript	contributed to the design of the analysis	Conceived and designed the experiments	-	YES
5073219	27765142	SS	2	contributed to the design of the analysis|contributed to the interpretation of the data, preparation and writing of the manuscript	contributed to the interpretation of the data, preparation and writing of the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
5073219	27765142	all authors	2	have read and approved the final manuscript	have read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6195020	30514988	AA	7	Contributed to conception and design|Acquisition of data|Drafting the article and revising it critically for important intellectualcontent|Final approval of the version to be published	Contributed to conception and design	Conceived and designed the experiments	Conceptualization	YES
6195020	30514988	AA	7	Contributed to conception and design|Acquisition of data|Drafting the article and revising it critically for important intellectualcontent|Final approval of the version to be published	Acquisition of data	Performed the experiments	Investigation	YES
6195020	30514988	AA	7	Contributed to conception and design|Acquisition of data|Drafting the article and revising it critically for important intellectualcontent|Final approval of the version to be published	Drafting the article and revising it critically for important intellectualcontent	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6195020	30514988	AA	7	Contributed to conception and design|Acquisition of data|Drafting the article and revising it critically for important intellectualcontent|Final approval of the version to be published	Final approval of the version to be published	-	-	NO
6195020	30514988	KA	7	Contributed to conception and design|Acquisition of data|Analysis and interpretation of data|Drafting the article and revising it critically for important intellectualcontent|Final approval of the version to be published	Contributed to conception and design	Conceived and designed the experiments	Conceptualization	YES
6195020	30514988	KA	7	Contributed to conception and design|Acquisition of data|Analysis and interpretation of data|Drafting the article and revising it critically for important intellectualcontent|Final approval of the version to be published	Acquisition of data	Performed the experiments	Investigation	YES
6195020	30514988	KA	7	Contributed to conception and design|Acquisition of data|Analysis and interpretation of data|Drafting the article and revising it critically for important intellectualcontent|Final approval of the version to be published	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
6195020	30514988	KA	7	Contributed to conception and design|Acquisition of data|Analysis and interpretation of data|Drafting the article and revising it critically for important intellectualcontent|Final approval of the version to be published	Drafting the article and revising it critically for important intellectualcontent	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6195020	30514988	KA	7	Contributed to conception and design|Acquisition of data|Analysis and interpretation of data|Drafting the article and revising it critically for important intellectualcontent|Final approval of the version to be published	Final approval of the version to be published	-	-	NO
6195020	30514988	MA	7	Contributed to conception and design|Acquisition of data|Analysis and interpretation of data|Drafting the article and revising it critically for important intellectualcontent|Final approval of the version to be published	Contributed to conception and design	Conceived and designed the experiments	Conceptualization	YES
6195020	30514988	MA	7	Contributed to conception and design|Acquisition of data|Analysis and interpretation of data|Drafting the article and revising it critically for important intellectualcontent|Final approval of the version to be published	Acquisition of data	Performed the experiments	Investigation	YES
6195020	30514988	MA	7	Contributed to conception and design|Acquisition of data|Analysis and interpretation of data|Drafting the article and revising it critically for important intellectualcontent|Final approval of the version to be published	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
6195020	30514988	MA	7	Contributed to conception and design|Acquisition of data|Analysis and interpretation of data|Drafting the article and revising it critically for important intellectualcontent|Final approval of the version to be published	Drafting the article and revising it critically for important intellectualcontent	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6195020	30514988	MA	7	Contributed to conception and design|Acquisition of data|Analysis and interpretation of data|Drafting the article and revising it critically for important intellectualcontent|Final approval of the version to be published	Final approval of the version to be published	-	-	NO
6195020	30514988	SA	7	Contributed to conception and design|Acquisition of data|Drafting the article and revising it critically for important intellectualcontent|Final approval of the version to be published	Contributed to conception and design	Conceived and designed the experiments	Conceptualization	YES
6195020	30514988	SA	7	Contributed to conception and design|Acquisition of data|Drafting the article and revising it critically for important intellectualcontent|Final approval of the version to be published	Acquisition of data	Performed the experiments	Investigation	YES
6195020	30514988	SA	7	Contributed to conception and design|Acquisition of data|Drafting the article and revising it critically for important intellectualcontent|Final approval of the version to be published	Drafting the article and revising it critically for important intellectualcontent	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6195020	30514988	SA	7	Contributed to conception and design|Acquisition of data|Drafting the article and revising it critically for important intellectualcontent|Final approval of the version to be published	Final approval of the version to be published	-	-	NO
5331655	28245871	CM	2	generated the ipsc cell cultures and performed rna extraction	generated the ipsc cell cultures and performed rna extraction	Performed the experiments	Investigation	YES
5331655	28245871	FHG	2	provided support for sequencing and data generation	provided support for sequencing and data generation	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5331655	28245871	GB	2	designed the study, assisted in the interpretation of results and wrote the manuscript	designed the study, assisted in the interpretation of results and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5331655	28245871	LR	2	contributed to the design, performed bioinformatic analyses, and wrote the manuscript	contributed to the design, performed bioinformatic analyses, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5331655	28245871	MC	2	performed initial processing of the rna seq data	performed initial processing of the rna seq data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5331655	28245871	S-HC	2	prepared the samples for rna sequencing	prepared the samples for rna sequencing	Performed the experiments	Investigation	YES
5331655	28245871	SB	2	provided support for sequencing and data generation	provided support for sequencing and data generation	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5331655	28245871	TK	2	provided support for sequencing and data generation	provided support for sequencing and data generation	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5331655	28245871	TP	2	provided support for sequencing and data generation	provided support for sequencing and data generation	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
6004735	29922462	Amina Malik	7	data management. Khabir ahmad: review and editing	data management. Khabir ahmad: review and editing	Analyzed the data|Wrote the paper	Data curation|Writing - Review & Editing	YES
6004735	29922462	Irfan Ashraf	7	first proposal and draft and conducting the study	first proposal and draft and conducting the study	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6004735	29922462	Obada Hasan	7	data analysis and manuscript writing and editing	data analysis and manuscript writing and editing	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
6004735	29922462	Shahryar Noordin	7	review and editing and approval	review and editing and approval	Wrote the paper	Writing - Review & Editing	YES
6004735	29922462	Yasir Muhib	7	manuscript witting	manuscript witting	-	-	NO
5572258	28878797	All authors	2	have read and approved the final version submitted	have read and approved the final version submitted	-	-	NO
5572258	28878797	HY	2	conceived and directed this study, designed and performed the experiments, analyzed the data, wrote and revised the manuscript	conceived and directed this study, designed and performed the experiments, analyzed the data, wrote and revised the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
5572258	28878797	MO	2	performed the experiments, analyzed the data	performed the experiments, analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5572258	28878797	WC	2	performed the experiments, analyzed the data	performed the experiments, analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5572258	28878797	XH	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5572258	28878797	XT	2	performed the experiments, analyzed the data	performed the experiments, analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5572258	28878797	YL	2	performed the experiments, analyzed the data	performed the experiments, analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5572258	28878797	YS	2	performed the experiments, analyzed the data	performed the experiments, analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6195022	30514994	Each author	2	participated in each step of research	participated in each step of research	-	-	NO
5075717	27774955	All authors	2	made contributions to the conception of this study, were involved in revising the manuscript and gave final approval of the version to be published	made contributions to the conception of this study, were involved in revising the manuscript and gave final approval of the version to be published	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5075717	27774955	BVH	2	made contributions to the data acquisition	made contributions to the data acquisition	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5075717	27774955	MPL	2	made contributions to the data acquisition	made contributions to the data acquisition	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5075717	27774955	RD	2	made contributions to the data acquisition	made contributions to the data acquisition	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5075717	27774955	SK	2	made contributions to the data acquisition	made contributions to the data acquisition	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5075717	27774955	SO	2	made contributions to the data acquisition	made contributions to the data acquisition	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5075717	27774955	TPM	2	made contributions to the data acquisition	made contributions to the data acquisition	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5075717	27774955	WWW	2	made contributions to the data acquisition	made contributions to the data acquisition	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4406612	25901356	MHL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406612	25901356	MHL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406612	25901356	MHL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406612	25901356	MHL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406612	25901356	MHL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406612	25901356	MR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406612	25901356	MR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406612	25901356	MR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406612	25901356	MR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406612	25901356	MR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406612	25901356	MRA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406612	25901356	MRA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406612	25901356	MRA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406612	25901356	MRA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406612	25901356	MRA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5331681	28245789	AJC	1	Collection and preparation of fly embryos|Groucho chip-seq and sequencing library preparation|Manuscript writing and figure generation	Collection and preparation of fly embryos	-	-	NO
5331681	28245789	AJC	1	Collection and preparation of fly embryos|Groucho chip-seq and sequencing library preparation|Manuscript writing and figure generation	Groucho chip-seq and sequencing library preparation	Performed the experiments	Investigation	YES
5331681	28245789	AJC	1	Collection and preparation of fly embryos|Groucho chip-seq and sequencing library preparation|Manuscript writing and figure generation	Manuscript writing and figure generation	Wrote the paper	Visualization|Writing - Original Draft	YES
5331681	28245789	KC	1	Collection and preparation of fly embryos|Chromatin-associated rna isolation and sequencing library preparation	Collection and preparation of fly embryos	-	-	NO
5331681	28245789	KC	1	Collection and preparation of fly embryos|Chromatin-associated rna isolation and sequencing library preparation	Chromatin-associated rna isolation and sequencing library preparation	Performed the experiments	Investigation	YES
5331681	28245789	MC	1	Collection and preparation of fly embryos|Chromatin-associated rna isolation and sequencing library preparation|Sequencing data processing and analysis|Manuscript writing and figure generation	Collection and preparation of fly embryos	-	-	NO
5331681	28245789	MC	1	Collection and preparation of fly embryos|Chromatin-associated rna isolation and sequencing library preparation|Sequencing data processing and analysis|Manuscript writing and figure generation	Chromatin-associated rna isolation and sequencing library preparation	Performed the experiments	Investigation	YES
5331681	28245789	MC	1	Collection and preparation of fly embryos|Chromatin-associated rna isolation and sequencing library preparation|Sequencing data processing and analysis|Manuscript writing and figure generation	Sequencing data processing and analysis	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5331681	28245789	MC	1	Collection and preparation of fly embryos|Chromatin-associated rna isolation and sequencing library preparation|Sequencing data processing and analysis|Manuscript writing and figure generation	Manuscript writing and figure generation	Wrote the paper	Visualization|Writing - Original Draft	YES
5331681	28245789	MWK	1	Collection and preparation of fly embryos|Groucho chip-seq and sequencing library preparation	Collection and preparation of fly embryos	-	-	NO
5331681	28245789	MWK	1	Collection and preparation of fly embryos|Groucho chip-seq and sequencing library preparation	Groucho chip-seq and sequencing library preparation	Performed the experiments	Investigation	YES
5331681	28245789	SDG	1	Total mrna sequencing library preparation	Total mrna sequencing library preparation	Performed the experiments	Investigation	YES
5331681	28245789	WTC	1	Collection and preparation of fly embryos	Collection and preparation of fly embryos	-	-	NO
5331681	28245789	WTJ	1	Total mrna isolation	Total mrna isolation	Performed the experiments	Investigation	YES
5572266	28878787	IA	PLoS52	analyzed the data|reviewed and revised the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5572266	28878787	IA	PLoS52	analyzed the data|reviewed and revised the paper	reviewed and revised the paper	Wrote the paper	Writing - Review & Editing	YES
5572266	28878787	MK	PLoS52	reviewed and revised the paper	reviewed and revised the paper	Wrote the paper	Writing - Review & Editing	YES
5572266	28878787	PZ	PLoS52	reviewed and revised the paper	reviewed and revised the paper	Wrote the paper	Writing - Review & Editing	YES
5572266	28878787	QJ	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5572266	28878787	SA	PLoS52	performed the experiments|analyzed the data|wrote the paper|corrected the english language for the paper	performed the experiments	Performed the experiments	Investigation	YES
5572266	28878787	SA	PLoS52	performed the experiments|analyzed the data|wrote the paper|corrected the english language for the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5572266	28878787	SA	PLoS52	performed the experiments|analyzed the data|wrote the paper|corrected the english language for the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5572266	28878787	SA	PLoS52	performed the experiments|analyzed the data|wrote the paper|corrected the english language for the paper	corrected the english language for the paper	Wrote the paper	Writing - Review & Editing	YES
5572266	28878787	TC	PLoS52	conceived and designed the experiments|reviewed and revised the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5572266	28878787	TC	PLoS52	conceived and designed the experiments|reviewed and revised the paper	reviewed and revised the paper	Wrote the paper	Writing - Review & Editing	YES
5572266	28878787	XM	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5572266	28878787	XR	PLoS52	conceived and designed the experiments|reviewed and revised the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5572266	28878787	XR	PLoS52	conceived and designed the experiments|reviewed and revised the paper	reviewed and revised the paper	Wrote the paper	Writing - Review & Editing	YES
5572266	28878787	YX	PLoS52	performed the experiments|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5572266	28878787	YX	PLoS52	performed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5572266	28878787	ZD	PLoS52	reviewed and revised the paper	reviewed and revised the paper	Wrote the paper	Writing - Review & Editing	YES
5572266	28878787	ZJ	PLoS52	conceived and designed the experiments|reviewed and revised the paper|corrected the english language for the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5572266	28878787	ZJ	PLoS52	conceived and designed the experiments|reviewed and revised the paper|corrected the english language for the paper	reviewed and revised the paper	Wrote the paper	Writing - Review & Editing	YES
5572266	28878787	ZJ	PLoS52	conceived and designed the experiments|reviewed and revised the paper|corrected the english language for the paper	corrected the english language for the paper	Wrote the paper	Writing - Review & Editing	YES
6004769	29922460	GT	2	edited part of the manuscript and had lead role in the esmsc course	edited part of the manuscript and had lead role in the esmsc course	Wrote the paper	Writing - Review & Editing	YES
6004769	29922460	JH	2	have equal contribution and drafted the manuscript|is the lead coordinator of the emerg research network	have equal contribution and drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
6004769	29922460	JH	2	have equal contribution and drafted the manuscript|is the lead coordinator of the emerg research network	is the lead coordinator of the emerg research network	Performed the experiments	Investigation|Project administration	YES
6004769	29922460	MS	2	have equal contribution and drafted the manuscript	have equal contribution and drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
6195033	30514993	all authors	2	participated in all steps of preparation of this article	participated in all steps of preparation of this article	-	-	NO
4406614	25902035	DSS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406614	25902035	DSS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406614	25902035	DSS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406614	25902035	DSS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406614	25902035	DSS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406614	25902035	EAC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406614	25902035	EAC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406614	25902035	EAC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406614	25902035	EAC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406614	25902035	EAC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406614	25902035	JC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406614	25902035	JC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406614	25902035	JC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406614	25902035	PG	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406614	25902035	PG	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4499384	26221542	Andreas Rempen	2	critically commented on every step of the process	critically commented on every step of the process	-	-	NO
4499384	26221542	Dirk Bottke	2	critically commented on every step of the process	critically commented on every step of the process	-	-	NO
4499384	26221542	Florian Ebner	2	wrote the paper with the	wrote the paper with the	Wrote the paper	Writing - Original Draft	YES
4499384	26221542	Gerlo Witucki	2	contributed equally to the paper	contributed equally to the paper	-	-	NO
4499384	26221542	Lukas Schwentner	2	critically commented on every step of the process	critically commented on every step of the process	-	-	NO
4499384	26221542	Niko Degregorio	2	contributed equally to the paper	contributed equally to the paper	-	-	NO
4499384	26221542	Nikolaus Degregorio	2	helped with the wrote the paper with the	helped with the wrote the paper with the	Wrote the paper	Writing - Original Draft	YES
4499384	26221542	Wolfgang Janni	2	critically commented on every step of the process	critically commented on every step of the process	-	-	NO
4958083	27447823	AAL	2	conceived the study and participated in its design	conceived the study and participated in its design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4958083	27447823	CWM	2	conceived the study and participated in its design|included the patients for the study	conceived the study and participated in its design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4958083	27447823	CWM	2	conceived the study and participated in its design|included the patients for the study	included the patients for the study	-	-	NO
4958083	27447823	MCH	2	conceived the study and participated in its design|participated in the interpretation of the results and helped in drafting the manuscript	conceived the study and participated in its design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4958083	27447823	MCH	2	conceived the study and participated in its design|participated in the interpretation of the results and helped in drafting the manuscript	participated in the interpretation of the results and helped in drafting the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4958083	27447823	NEM	2	implemented the active contour method, carried out the data analysis, interpreted the results and drafted the manuscript	implemented the active contour method, carried out the data analysis, interpreted the results and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4958083	27447823	RB	2	conceived the study and participated in its design	conceived the study and participated in its design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6195034	30515002	Each author	2	participated in each step of research|gave final approval for final version of article	participated in each step of research	-	-	NO
6195034	30515002	Each author	2	participated in each step of research|gave final approval for final version of article	gave final approval for final version of article	-	-	NO
6195034	30515002	G.R.	2	revised it critically	revised it critically	Wrote the paper	Writing - Review & Editing	YES
6004772	29922463	Ashok Rijhwani	2	reviewed the results, and reviewed and provided critical feedback for the manuscript	reviewed the results, and reviewed and provided critical feedback for the manuscript	Wrote the paper	Writing - Review & Editing	YES
6004772	29922463	Dr Veerabhadra	2	reviewed the results, and reviewed and provided critical feedback for the manuscript	reviewed the results, and reviewed and provided critical feedback for the manuscript	Wrote the paper	Writing - Review & Editing	YES
5331693	28245801	DAK	2	supervised the study	supervised the study	-	Supervision	YES
5331693	28245801	KN	2	conceived the project|wrote the manuscript with the|supervised the study	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5331693	28245801	KN	2	conceived the project|wrote the manuscript with the|supervised the study	wrote the manuscript with the	Wrote the paper	Writing - Original Draft	YES
5331693	28245801	KN	2	conceived the project|wrote the manuscript with the|supervised the study	supervised the study	-	Supervision	YES
5331693	28245801	RL	2	conceived the project|conducted transcriptome and translatome experiments, and analyzed the data with|wrote the manuscript with the	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5331693	28245801	RL	2	conceived the project|conducted transcriptome and translatome experiments, and analyzed the data with|wrote the manuscript with the	conducted transcriptome and translatome experiments, and analyzed the data with	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5331693	28245801	RL	2	conceived the project|conducted transcriptome and translatome experiments, and analyzed the data with|wrote the manuscript with the	wrote the manuscript with the	Wrote the paper	Writing - Original Draft	YES
5331693	28245801	RW	2	conducted the competitive growth assays	conducted the competitive growth assays	Performed the experiments	Investigation	YES
5331693	28245801	SSche	2	supervised the study	supervised the study	-	Supervision	YES
5331693	28245801	SSi	2	helped with the and analyzed the data with	helped with the and analyzed the data with	Analyzed the data	Formal analysis	YES
5331693	28245801	all other authors	2	helped with the wrote the manuscript with the	helped with the wrote the manuscript with the	Wrote the paper	Writing - Original Draft	YES
5572287	28878783	AP	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5572287	28878783	BS	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5572287	28878783	MB	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
1847832	17391522	The author	2	is responsible for the entire paper	is responsible for the entire paper	-	-	NO
4406615	25901361	CELF	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406615	25901361	CELF	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406615	25901361	CRR	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4406615	25901361	CRR	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4406615	25901361	CRR	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406615	25901361	LAR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406615	25901361	LAR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406615	25901361	LAR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406615	25901361	LAR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406615	25901361	LAR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406615	25901361	MBL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4406615	25901361	MCB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4406615	25901361	OJL	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406615	25901361	OJL	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406615	25901361	SRF	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406615	25901361	SRF	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6004773	29922461	AP	7	conception, design, acquisition of the data and drafting of the article|acquisition of the data and writing of the manuscript	conception, design, acquisition of the data and drafting of the article	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
6004773	29922461	AP	7	conception, design, acquisition of the data and drafting of the article|acquisition of the data and writing of the manuscript	acquisition of the data and writing of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6004773	29922461	DPGD	7	interpretation of the data and critical revisions|critical revisions and final approval	interpretation of the data and critical revisions	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
6004773	29922461	DPGD	7	interpretation of the data and critical revisions|critical revisions and final approval	critical revisions and final approval	Wrote the paper	Writing - Review & Editing	YES
6004773	29922461	MF	7	acquisition of the data and writing of the manuscript	acquisition of the data and writing of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6004773	29922461	MM	7	conception, design, acquisition of the data and drafting of the article|interpretation of the data and critical revisions|critical revisions and final approval	conception, design, acquisition of the data and drafting of the article	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
6004773	29922461	MM	7	conception, design, acquisition of the data and drafting of the article|interpretation of the data and critical revisions|critical revisions and final approval	interpretation of the data and critical revisions	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
6004773	29922461	MM	7	conception, design, acquisition of the data and drafting of the article|interpretation of the data and critical revisions|critical revisions and final approval	critical revisions and final approval	Wrote the paper	Writing - Review & Editing	YES
6004773	29922461	MaM	7	acquisition of the data and writing of the manuscript	acquisition of the data and writing of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6265598	30514995	S.M.	2	alone prepared this article and made final proof reading by himself	alone prepared this article and made final proof reading by himself	Wrote the paper	Writing - Original Draft	YES
1852567	17407602	NS	2	participated equally in the research, writing and revisions for this manuscript|both read and approved the final manuscript	participated equally in the research, writing and revisions for this manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
1852567	17407602	NS	2	participated equally in the research, writing and revisions for this manuscript|both read and approved the final manuscript	both read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
1852567	17407602	RAP	2	participated equally in the research, writing and revisions for this manuscript|both read and approved the final manuscript	participated equally in the research, writing and revisions for this manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
1852567	17407602	RAP	2	participated equally in the research, writing and revisions for this manuscript|both read and approved the final manuscript	both read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
3662154	23737717	Jiancheng Wang	2	contributed equally to this work	contributed equally to this work	-	-	NO
3662154	23737717	Yajing Guan	2	contributed equally to this work	contributed equally to this work	-	-	NO
4967048	27473290	All authors	2	participated in the conception of the study and design	participated in the conception of the study and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4967048	27473290	RH	2	assisted in the revising of the manuscript	assisted in the revising of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4967048	27473290	RM	2	assisted in the interpretation of the data and the revising of the manuscript	assisted in the interpretation of the data and the revising of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4967048	27473290	TL	2	assisted in the ct data analysis and the revising of the manuscript	assisted in the ct data analysis and the revising of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4967048	27473290	WM	2	created the image acquisition protocols, acquired images, carried out the data collection and analysis, and drafted manuscript	created the image acquisition protocols, acquired images, carried out the data collection and analysis, and drafted manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Visualization|Writing - Original Draft	YES
5331709	28245787	BF	PLoS52	assisted with the wrote the paper with the	assisted with the wrote the paper with the	Wrote the paper	Writing - Original Draft	YES
5331709	28245787	DW	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5331709	28245787	DWC	PLoS52	assisted with the wrote the paper with the	assisted with the wrote the paper with the	Wrote the paper	Writing - Original Draft	YES
5331709	28245787	JL	PLoS52	assisted with the wrote the paper with the	assisted with the wrote the paper with the	Wrote the paper	Writing - Original Draft	YES
5331709	28245787	LC	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper with the	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5331709	28245787	LC	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper with the	performed the experiments	Performed the experiments	Investigation	YES
5331709	28245787	LC	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper with the	analyzed the data	Analyzed the data	Formal analysis	YES
5331709	28245787	LC	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper with the	wrote the paper with the	Wrote the paper	Writing - Original Draft	YES
5331709	28245787	LQC	PLoS52	assisted with the wrote the paper with the	assisted with the wrote the paper with the	Wrote the paper	Writing - Original Draft	YES
5331709	28245787	MMX	PLoS52	performed the experiments|wrote the paper with the	performed the experiments	Performed the experiments	Investigation	YES
5331709	28245787	MMX	PLoS52	performed the experiments|wrote the paper with the	wrote the paper with the	Wrote the paper	Writing - Original Draft	YES
5331709	28245787	SYX	PLoS52	assisted with the wrote the paper with the	assisted with the wrote the paper with the	Wrote the paper	Writing - Original Draft	YES
5331709	28245787	YL	PLoS52	assisted with the wrote the paper with the	assisted with the wrote the paper with the	Wrote the paper	Writing - Original Draft	YES
5331709	28245787	ZFF	PLoS52	assisted with the wrote the paper with the	assisted with the wrote the paper with the	Wrote the paper	Writing - Original Draft	YES
5331709	28245787	ZGY	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
6282908	30524160	A.K.	2	gave substantial contributions to the conception or design of the work in acquisition, analysis, or interpretation of data for the work	gave substantial contributions to the conception or design of the work in acquisition, analysis, or interpretation of data for the work	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
6282908	30524160	Each author	2	had a part in article preparing for drafting or revising it critically for important intellectual content, and all authors gave final approval of the version to be published and agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	had a part in article preparing for drafting or revising it critically for important intellectual content, and all authors gave final approval of the version to be published and agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6282908	30524160	H.A.	2	gave substantial contributions to the conception or design of the work in acquisition, analysis, or interpretation of data for the work	gave substantial contributions to the conception or design of the work in acquisition, analysis, or interpretation of data for the work	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
6282908	30524160	S.S.	2	gave substantial contributions to the conception or design of the work in acquisition, analysis, or interpretation of data for the work	gave substantial contributions to the conception or design of the work in acquisition, analysis, or interpretation of data for the work	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
4406618	25901964	CC	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406618	25901964	CC	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406618	25901964	CC	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406618	25901964	CC	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406618	25901964	CT	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4406618	25901964	CT	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406618	25901964	GZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406618	25901964	GZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406618	25901964	GZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406618	25901964	GZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406618	25901964	JZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406618	25901964	JZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4406618	25901964	JZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406618	25901964	LZ	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4406618	25901964	LZ	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406618	25901964	ML	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406618	25901964	MN	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4406618	25901964	MN	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406618	25901964	SH	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406618	25901964	SH	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4406618	25901964	SH	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406618	25901964	SX	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4406618	25901964	SX	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406618	25901964	WM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4406618	25901964	WM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406618	25901964	Y. Zhang	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406618	25901964	Y. Zhang	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406618	25901964	Y. Zhou	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406618	25901964	Y. Zhou	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406618	25901964	YL	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5572293	28878802	BL	PLoS52	designed the project, supervised the works, and revised the draft manuscript	designed the project, supervised the works, and revised the draft manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
5572293	28878802	JY	PLoS52	produced the sesame ssr data, developed the online database, and drafted the manuscript	produced the sesame ssr data, developed the online database, and drafted the manuscript	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Software|Writing - Original Draft	YES
5572293	28878802	KD	PLoS52	produced the sesame ssr data, developed the online database, and drafted the manuscript|performed the experiments	produced the sesame ssr data, developed the online database, and drafted the manuscript	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Software|Writing - Original Draft	YES
5572293	28878802	KD	PLoS52	produced the sesame ssr data, developed the online database, and drafted the manuscript|performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5572293	28878802	NC	PLoS52	designed the project, supervised the works, and revised the draft manuscript	designed the project, supervised the works, and revised the draft manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
5572293	28878802	XZ	PLoS52	designed the project, supervised the works, and revised the draft manuscript	designed the project, supervised the works, and revised the draft manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
6004778	29922465	Elissavet Astyrakaki	2	was the specialized anesthesiologist	was the specialized anesthesiologist	-	-	NO
6004778	29922465	Emmanuel Chrysos	2	the leader of the team and the head of the department	the leader of the team and the head of the department	-	Supervision	YES
6004778	29922465	Evangelos Blevrakis	2	was the leading surgeon and contributed in the narration of the manuscript and the creation of the figures	was the leading surgeon and contributed in the narration of the manuscript and the creation of the figures	-	Visualization	YES
6004778	29922465	Maria Raissaki	2	was the specialized radiologist and contributed in the diagnosis of the case and the creation of the figures	was the specialized radiologist and contributed in the diagnosis of the case and the creation of the figures	Performed the experiments	Investigation|Visualization	YES
6004778	29922465	Nelli Kholcheva	2	contributed in the radiological diagnosis of the case	contributed in the radiological diagnosis of the case	Performed the experiments	Investigation	YES
6004778	29922465	Sofia Xenaki	2	assisted in the operation and contributed in the narration of the manuscripts	assisted in the operation and contributed in the narration of the manuscripts	Performed the experiments	Investigation	YES
3546443	23346390	J. Blanchard	2	were involved in the original data collection, and contributed to the review and finalization of the paper	were involved in the original data collection, and contributed to the review and finalization of the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
3546443	23346390	L. Avery	2	were involved in the original data collection, and contributed to the review and finalization of the paper	were involved in the original data collection, and contributed to the review and finalization of the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
3546443	23346390	M. Becker	2	conceived the study, participated in its design, coordinated implementation of the original data collection, and drafted the paper	conceived the study, participated in its design, coordinated implementation of the original data collection, and drafted the paper	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Project administration|Writing - Original Draft	YES
3546443	23346390	P. Bhattacharjee	2	were involved in the original data collection, and contributed to review and finalization of the paper	were involved in the original data collection, and contributed to review and finalization of the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
3546443	23346390	S. Halli	2	were involved in the original data collection, and contributed to review and finalization of the paper	were involved in the original data collection, and contributed to review and finalization of the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
3546443	23346390	S. Mishra	2	participated in study design, assisted with survey implementation, conducted the analysis, and drafted the paper	participated in study design, assisted with survey implementation, conducted the analysis, and drafted the paper	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
3546443	23346390	S. Moses	2	were involved in the original data collection, and contributed to the review and finalization of the paper	were involved in the original data collection, and contributed to the review and finalization of the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
3546443	23346390	S. Ramanaik	2	were involved in the original data collection, and contributed to review and finalization of the paper	were involved in the original data collection, and contributed to review and finalization of the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
3546443	23346390	T. Ragahavendra	2	were involved in the original data collection, and contributed to review and finalization of the paper	were involved in the original data collection, and contributed to review and finalization of the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5120379	27990191	K. Akeda	2	had data collection	had data collection	Performed the experiments	Investigation	YES
5120379	27990191	R. Guo	2	drafted the manuscript, did first selection of articles, and assessed the quality of the papers	drafted the manuscript, did first selection of articles, and assessed the quality of the papers	Wrote the paper	Validation|Writing - Original Draft	YES
5120379	27990191	T. Kondo	2	had data collection	had data collection	Performed the experiments	Investigation	YES
5120379	27990191	T. Mizuno	2	assessed the quality of the papers, and revised the manuscript critically for its content	assessed the quality of the papers, and revised the manuscript critically for its content	Wrote the paper	Validation|Writing - Review & Editing	YES
5120379	27990191	T. Sakakibara	2	had data collection	had data collection	Performed the experiments	Investigation	YES
5120379	27990191	Y. Kasai	2	helped to draft and to correct the manuscript	helped to draft and to correct the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6282909	30524162	Each author	2	had a part in article preparing for drafting or revising it critically for important intellectual content, and all authors gave final approval of the version to be published and agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	had a part in article preparing for drafting or revising it critically for important intellectual content, and all authors gave final approval of the version to be published and agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6282909	30524162	N.M.	2	gave substantial contributions to the conception or design of the work in acquisition, analysis, or interpretation of data for the work	gave substantial contributions to the conception or design of the work in acquisition, analysis, or interpretation of data for the work	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
6282909	30524162	V.B.	2	gave substantial contributions to the conception or design of the work in acquisition, analysis, or interpretation of data for the work	gave substantial contributions to the conception or design of the work in acquisition, analysis, or interpretation of data for the work	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
4975728	27495914	AC	2	carried out the imaging experiments|analysed and interpreted the data	carried out the imaging experiments	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
4975728	27495914	AC	2	carried out the imaging experiments|analysed and interpreted the data	analysed and interpreted the data	Analyzed the data	Formal analysis	YES
4975728	27495914	AD	2	carried out the monte carlo simulations	carried out the monte carlo simulations	Performed the experiments	Formal analysis|Investigation	YES
4975728	27495914	All authors	2	critically revised and approved the final manuscript	critically revised and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4975728	27495914	CC	2	designed and manufactured the phantom	designed and manufactured the phantom	Conceived and designed the experiments	-	YES
4975728	27495914	CL	2	designed and manufactured the phantom	designed and manufactured the phantom	Conceived and designed the experiments	-	YES
4975728	27495914	GF	2	conceived of and designed the study	conceived of and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4975728	27495914	JG	2	conceived of and designed the study|designed and manufactured the phantom|carried out the imaging experiments|analysed and interpreted the data|drafted the manuscript	conceived of and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4975728	27495914	JG	2	conceived of and designed the study|designed and manufactured the phantom|carried out the imaging experiments|analysed and interpreted the data|drafted the manuscript	designed and manufactured the phantom	Conceived and designed the experiments	-	YES
4975728	27495914	JG	2	conceived of and designed the study|designed and manufactured the phantom|carried out the imaging experiments|analysed and interpreted the data|drafted the manuscript	carried out the imaging experiments	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
4975728	27495914	JG	2	conceived of and designed the study|designed and manufactured the phantom|carried out the imaging experiments|analysed and interpreted the data|drafted the manuscript	analysed and interpreted the data	Analyzed the data	Formal analysis	YES
4975728	27495914	JG	2	conceived of and designed the study|designed and manufactured the phantom|carried out the imaging experiments|analysed and interpreted the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4975728	27495914	MT	2	conceived of and designed the study	conceived of and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5572335	28878788	BL	PLoS52	accomplished the observation of embryo	accomplished the observation of embryo	Performed the experiments	Investigation	YES
5572335	28878788	DZ	PLoS52	performed spraying of ethephon and counted up the ratio of bisexual flowers	performed spraying of ethephon and counted up the ratio of bisexual flowers	Performed the experiments	Investigation	YES
5572335	28878788	FZ	PLoS52	performed spraying of ethephon and counted up the ratio of bisexual flowers	performed spraying of ethephon and counted up the ratio of bisexual flowers	Performed the experiments	Investigation	YES
5572335	28878788	HL	PLoS52	performed qrt pcr|helped the article proofread	performed qrt pcr	Performed the experiments	Investigation	YES
5572335	28878788	HL	PLoS52	performed qrt pcr|helped the article proofread	helped the article proofread	-	-	NO
5572335	28878788	HX	PLoS52	contributed to the acquisition of materials	contributed to the acquisition of materials	Contributed reagents/materials/analysis tools	Resources	YES
5572335	28878788	JN	PLoS52	contributed to the acquisition of materials	contributed to the acquisition of materials	Contributed reagents/materials/analysis tools	Resources	YES
5572335	28878788	JZ	PLoS52	conducted gene expression analysis|helped the article proofread	conducted gene expression analysis	Performed the experiments	Investigation	YES
5572335	28878788	JZ	PLoS52	conducted gene expression analysis|helped the article proofread	helped the article proofread	-	-	NO
5572335	28878788	LC	PLoS52	conceived the project and its components|contributed to the acquisition of materials|accomplished the observation of embryo|performed spraying of ethephon and counted up the ratio of bisexual flowers|conducted gene expression analysis|performed qrt pcr|wrote the paper	conceived the project and its components	Conceived and designed the experiments	Conceptualization	YES
5572335	28878788	LC	PLoS52	conceived the project and its components|contributed to the acquisition of materials|accomplished the observation of embryo|performed spraying of ethephon and counted up the ratio of bisexual flowers|conducted gene expression analysis|performed qrt pcr|wrote the paper	contributed to the acquisition of materials	Contributed reagents/materials/analysis tools	Resources	YES
5572335	28878788	LC	PLoS52	conceived the project and its components|contributed to the acquisition of materials|accomplished the observation of embryo|performed spraying of ethephon and counted up the ratio of bisexual flowers|conducted gene expression analysis|performed qrt pcr|wrote the paper	accomplished the observation of embryo	Performed the experiments	Investigation	YES
5572335	28878788	LC	PLoS52	conceived the project and its components|contributed to the acquisition of materials|accomplished the observation of embryo|performed spraying of ethephon and counted up the ratio of bisexual flowers|conducted gene expression analysis|performed qrt pcr|wrote the paper	performed spraying of ethephon and counted up the ratio of bisexual flowers	Performed the experiments	Investigation	YES
5572335	28878788	LC	PLoS52	conceived the project and its components|contributed to the acquisition of materials|accomplished the observation of embryo|performed spraying of ethephon and counted up the ratio of bisexual flowers|conducted gene expression analysis|performed qrt pcr|wrote the paper	conducted gene expression analysis	Performed the experiments	Investigation	YES
5572335	28878788	LC	PLoS52	conceived the project and its components|contributed to the acquisition of materials|accomplished the observation of embryo|performed spraying of ethephon and counted up the ratio of bisexual flowers|conducted gene expression analysis|performed qrt pcr|wrote the paper	performed qrt pcr	Performed the experiments	Investigation	YES
5572335	28878788	LC	PLoS52	conceived the project and its components|contributed to the acquisition of materials|accomplished the observation of embryo|performed spraying of ethephon and counted up the ratio of bisexual flowers|conducted gene expression analysis|performed qrt pcr|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5572335	28878788	QW	PLoS52	performed spraying of ethephon and counted up the ratio of bisexual flowers	performed spraying of ethephon and counted up the ratio of bisexual flowers	Performed the experiments	Investigation	YES
5572335	28878788	SC	PLoS52	conceived the project and its components	conceived the project and its components	Conceived and designed the experiments	Conceptualization	YES
5572335	28878788	XL	PLoS52	conducted gene expression analysis	conducted gene expression analysis	Performed the experiments	Investigation	YES
4406621	25901969	AJ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406621	25901969	AJ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406621	25901969	AJ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406621	25901969	MY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406621	25901969	MY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406621	25901969	MY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406621	25901969	MY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5333379	28249569	AGD	PLoS5	Conceived and designed the analyses|Performed the meta-analysis|Wrote the paper	Conceived and designed the analyses	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
5333379	28249569	AGD	PLoS5	Conceived and designed the analyses|Performed the meta-analysis|Wrote the paper	Performed the meta-analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5333379	28249569	AGD	PLoS5	Conceived and designed the analyses|Performed the meta-analysis|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5333379	28249569	CMG	PLoS5	Conceived and designed the analyses|Performed and analysed new transcriptomes|Performed the meta-analysis|Wrote the paper	Conceived and designed the analyses	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
5333379	28249569	CMG	PLoS5	Conceived and designed the analyses|Performed and analysed new transcriptomes|Performed the meta-analysis|Wrote the paper	Performed and analysed new transcriptomes	Performed the experiments	Investigation	YES
5333379	28249569	CMG	PLoS5	Conceived and designed the analyses|Performed and analysed new transcriptomes|Performed the meta-analysis|Wrote the paper	Performed the meta-analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5333379	28249569	CMG	PLoS5	Conceived and designed the analyses|Performed and analysed new transcriptomes|Performed the meta-analysis|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5333379	28249569	CeA	PLoS5	Conceived and designed the analyses|Commented on the manuscript	Conceived and designed the analyses	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
5333379	28249569	CeA	PLoS5	Conceived and designed the analyses|Commented on the manuscript	Commented on the manuscript	-	-	NO
5333379	28249569	ChA	PLoS5	Conceived and designed the analyses|Commented on the manuscript	Conceived and designed the analyses	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
5333379	28249569	ChA	PLoS5	Conceived and designed the analyses|Commented on the manuscript	Commented on the manuscript	-	-	NO
5333379	28249569	DA	PLoS5	Performed and analysed new transcriptomes	Performed and analysed new transcriptomes	Performed the experiments	Investigation	YES
5333379	28249569	DAG	PLoS5	Performed and analysed new transcriptomes	Performed and analysed new transcriptomes	Performed the experiments	Investigation	YES
5333379	28249569	DH	PLoS5	Conceived and designed the analyses|Commented on the manuscript	Conceived and designed the analyses	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
5333379	28249569	DH	PLoS5	Conceived and designed the analyses|Commented on the manuscript	Commented on the manuscript	-	-	NO
5333379	28249569	DPM	PLoS5	Conceived and designed the analyses|Performed and analysed new transcriptomes|Commented on the manuscript	Conceived and designed the analyses	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
5333379	28249569	DPM	PLoS5	Conceived and designed the analyses|Performed and analysed new transcriptomes|Commented on the manuscript	Performed and analysed new transcriptomes	Performed the experiments	Investigation	YES
5333379	28249569	DPM	PLoS5	Conceived and designed the analyses|Performed and analysed new transcriptomes|Commented on the manuscript	Commented on the manuscript	-	-	NO
5333379	28249569	EG	PLoS5	Conceived and designed the analyses|Performed and analysed new transcriptomes|Commented on the manuscript	Conceived and designed the analyses	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
5333379	28249569	EG	PLoS5	Conceived and designed the analyses|Performed and analysed new transcriptomes|Commented on the manuscript	Performed and analysed new transcriptomes	Performed the experiments	Investigation	YES
5333379	28249569	EG	PLoS5	Conceived and designed the analyses|Performed and analysed new transcriptomes|Commented on the manuscript	Commented on the manuscript	-	-	NO
5333379	28249569	ELN	PLoS5	Conceived and designed the analyses|Performed and analysed new transcriptomes|Commented on the manuscript	Conceived and designed the analyses	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
5333379	28249569	ELN	PLoS5	Conceived and designed the analyses|Performed and analysed new transcriptomes|Commented on the manuscript	Performed and analysed new transcriptomes	Performed the experiments	Investigation	YES
5333379	28249569	ELN	PLoS5	Conceived and designed the analyses|Performed and analysed new transcriptomes|Commented on the manuscript	Commented on the manuscript	-	-	NO
5333379	28249569	FM	PLoS5	Conceived and designed the analyses|Commented on the manuscript	Conceived and designed the analyses	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
5333379	28249569	FM	PLoS5	Conceived and designed the analyses|Commented on the manuscript	Commented on the manuscript	-	-	NO
5333379	28249569	FN	PLoS5	Conceived and designed the analyses|Performed and analysed new transcriptomes|Commented on the manuscript	Conceived and designed the analyses	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
5333379	28249569	FN	PLoS5	Conceived and designed the analyses|Performed and analysed new transcriptomes|Commented on the manuscript	Performed and analysed new transcriptomes	Performed the experiments	Investigation	YES
5333379	28249569	FN	PLoS5	Conceived and designed the analyses|Performed and analysed new transcriptomes|Commented on the manuscript	Commented on the manuscript	-	-	NO
5333379	28249569	HLH	PLoS5	Conceived and designed the analyses|Commented on the manuscript	Conceived and designed the analyses	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
5333379	28249569	HLH	PLoS5	Conceived and designed the analyses|Commented on the manuscript	Commented on the manuscript	-	-	NO
5333379	28249569	HMGL	PLoS5	Conceived and designed the analyses|Commented on the manuscript	Conceived and designed the analyses	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
5333379	28249569	HMGL	PLoS5	Conceived and designed the analyses|Commented on the manuscript	Commented on the manuscript	-	-	NO
5333379	28249569	IG	PLoS5	Conceived and designed the analyses|Commented on the manuscript	Conceived and designed the analyses	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
5333379	28249569	IG	PLoS5	Conceived and designed the analyses|Commented on the manuscript	Commented on the manuscript	-	-	NO
5333379	28249569	JCB	PLoS5	Conceived and designed the analyses|Commented on the manuscript	Conceived and designed the analyses	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
5333379	28249569	JCB	PLoS5	Conceived and designed the analyses|Commented on the manuscript	Commented on the manuscript	-	-	NO
5333379	28249569	KN	PLoS5	Conceived and designed the analyses|Commented on the manuscript	Conceived and designed the analyses	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
5333379	28249569	KN	PLoS5	Conceived and designed the analyses|Commented on the manuscript	Commented on the manuscript	-	-	NO
5333379	28249569	MJFB	PLoS5	Conceived and designed the analyses|Commented on the manuscript	Conceived and designed the analyses	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
5333379	28249569	MJFB	PLoS5	Conceived and designed the analyses|Commented on the manuscript	Commented on the manuscript	-	-	NO
5333379	28249569	MLF	PLoS5	Conceived and designed the analyses|Commented on the manuscript	Conceived and designed the analyses	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
5333379	28249569	MLF	PLoS5	Conceived and designed the analyses|Commented on the manuscript	Commented on the manuscript	-	-	NO
5333379	28249569	OCBR	PLoS5	Conceived and designed the analyses|Commented on the manuscript	Conceived and designed the analyses	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
5333379	28249569	OCBR	PLoS5	Conceived and designed the analyses|Commented on the manuscript	Commented on the manuscript	-	-	NO
5333379	28249569	RFAM	PLoS5	Conceived and designed the analyses|Commented on the manuscript	Conceived and designed the analyses	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
5333379	28249569	RFAM	PLoS5	Conceived and designed the analyses|Commented on the manuscript	Commented on the manuscript	-	-	NO
5333379	28249569	RJP	PLoS5	Conceived and designed the analyses|Performed and analysed new transcriptomes|Performed the meta-analysis|Wrote the paper	Conceived and designed the analyses	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
5333379	28249569	RJP	PLoS5	Conceived and designed the analyses|Performed and analysed new transcriptomes|Performed the meta-analysis|Wrote the paper	Performed and analysed new transcriptomes	Performed the experiments	Investigation	YES
5333379	28249569	RJP	PLoS5	Conceived and designed the analyses|Performed and analysed new transcriptomes|Performed the meta-analysis|Wrote the paper	Performed the meta-analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5333379	28249569	RJP	PLoS5	Conceived and designed the analyses|Performed and analysed new transcriptomes|Performed the meta-analysis|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5333379	28249569	RPvR	PLoS5	Conceived and designed the analyses|Commented on the manuscript	Conceived and designed the analyses	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
5333379	28249569	RPvR	PLoS5	Conceived and designed the analyses|Commented on the manuscript	Commented on the manuscript	-	-	NO
5333379	28249569	SG	PLoS5	Performed and analysed new transcriptomes	Performed and analysed new transcriptomes	Performed the experiments	Investigation	YES
5333379	28249569	SMB	PLoS5	Conceived and designed the analyses|Commented on the manuscript	Conceived and designed the analyses	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
5333379	28249569	SMB	PLoS5	Conceived and designed the analyses|Commented on the manuscript	Commented on the manuscript	-	-	NO
5333379	28249569	VD	PLoS5	Conceived and designed the analyses|Performed the meta-analysis|Wrote the paper	Conceived and designed the analyses	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
5333379	28249569	VD	PLoS5	Conceived and designed the analyses|Performed the meta-analysis|Wrote the paper	Performed the meta-analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5333379	28249569	VD	PLoS5	Conceived and designed the analyses|Performed the meta-analysis|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5333379	28249569	YLC	PLoS5	Conceived and designed the analyses|Commented on the manuscript	Conceived and designed the analyses	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
5333379	28249569	YLC	PLoS5	Conceived and designed the analyses|Commented on the manuscript	Commented on the manuscript	-	-	NO
5333379	28249569	YP	PLoS5	Conceived and designed the analyses|Performed the meta-analysis|Wrote the paper	Conceived and designed the analyses	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
5333379	28249569	YP	PLoS5	Conceived and designed the analyses|Performed the meta-analysis|Wrote the paper	Performed the meta-analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5333379	28249569	YP	PLoS5	Conceived and designed the analyses|Performed the meta-analysis|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6008501	29928499	Hamza Cinar	1	Study design|Data collections|Writing	Study design	Conceived and designed the experiments	Methodology	YES
6008501	29928499	Hamza Cinar	1	Study design|Data collections|Writing	Data collections	Performed the experiments	Investigation	YES
6008501	29928499	Hamza Cinar	1	Study design|Data collections|Writing	Writing	Wrote the paper	-	YES
6008501	29928499	Ismail Alper Tarim	1	Writing	Writing	Wrote the paper	-	YES
6008501	29928499	Koray Topgul	1	Study design|Writing	Study design	Conceived and designed the experiments	Methodology	YES
6008501	29928499	Koray Topgul	1	Study design|Writing	Writing	Wrote the paper	-	YES
6008501	29928499	Savas Yuruker	1	Data analysis|Writing	Data analysis	Analyzed the data	Formal analysis	YES
6008501	29928499	Savas Yuruker	1	Data analysis|Writing	Writing	Wrote the paper	-	YES
6008501	29928499	Sercan Buyukakincak	1	Data analysis|Writing	Data analysis	Analyzed the data	Formal analysis	YES
6008501	29928499	Sercan Buyukakincak	1	Data analysis|Writing	Writing	Wrote the paper	-	YES
6008501	29928499	Tugrul Kesicioglu	1	Data collections	Data collections	Performed the experiments	Investigation	YES
6008501	29928499	Zafer Malazgirt	1	Study design	Study design	Conceived and designed the experiments	Methodology	YES
6008501	29928499	Zeliha Koc	1	Data collections	Data collections	Performed the experiments	Investigation	YES
6008501	29928499	Zeynep Saglam	1	Data collections	Data collections	Performed the experiments	Investigation	YES
6282910	30524163	all authors	2	gave final approval of the version to be published and agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	gave final approval of the version to be published and agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	-	-	NO
1892566	17519030	J.L.V.	2	have all read and approved the final manuscript	have all read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
1892566	17519030	J.M.	2	have all read and approved the final manuscript	have all read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
1892566	17519030	M.Y.R.	2	have all read and approved the final manuscript	have all read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6282911	30524170	A.K.	2	gave substantial contributions to the conception or design of the work in acquisition, analysis, or interpretation of data for the work	gave substantial contributions to the conception or design of the work in acquisition, analysis, or interpretation of data for the work	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
6282911	30524170	A.V.	2	gave substantial contributions to the conception or design of the work in acquisition, analysis, or interpretation of data for the work	gave substantial contributions to the conception or design of the work in acquisition, analysis, or interpretation of data for the work	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
6282911	30524170	C.C.	2	gave substantial contributions to the conception or design of the work in acquisition, analysis, or interpretation of data for the work	gave substantial contributions to the conception or design of the work in acquisition, analysis, or interpretation of data for the work	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
6282911	30524170	Each author	2	had a part in article preparing for drafting or revising it critically for important intellectual content, and all authors gave final approval of the version to be published and agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	had a part in article preparing for drafting or revising it critically for important intellectual content, and all authors gave final approval of the version to be published and agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6282911	30524170	F.A.	2	gave substantial contributions to the conception or design of the work in acquisition, analysis, or interpretation of data for the work	gave substantial contributions to the conception or design of the work in acquisition, analysis, or interpretation of data for the work	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
6282911	30524170	M.P.	2	gave substantial contributions to the conception or design of the work in acquisition, analysis, or interpretation of data for the work	gave substantial contributions to the conception or design of the work in acquisition, analysis, or interpretation of data for the work	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
6282911	30524170	S.E.	2	gave substantial contributions to the conception or design of the work in acquisition, analysis, or interpretation of data for the work	gave substantial contributions to the conception or design of the work in acquisition, analysis, or interpretation of data for the work	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
6282911	30524170	S.P.	2	gave substantial contributions to the conception or design of the work in acquisition, analysis, or interpretation of data for the work	gave substantial contributions to the conception or design of the work in acquisition, analysis, or interpretation of data for the work	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
6282911	30524170	Z.P.	2	gave substantial contributions to the conception or design of the work in acquisition, analysis, or interpretation of data for the work	gave substantial contributions to the conception or design of the work in acquisition, analysis, or interpretation of data for the work	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
4506847	26236713	Kaizheng Chen	2	contributed equally to the studies	contributed equally to the studies	-	-	NO
4506847	26236713	Yupeng Zhao	2	contributed equally to the studies	contributed equally to the studies	-	-	NO
4406624	25902356	TXY	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406624	25902356	XQ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406624	25902356	XQ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406624	25902356	XQ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406624	25902356	XZ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406624	25902356	YL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406624	25902356	YL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406624	25902356	YL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5572355	28878799	AA	PLoS52	performed the experiments|analyzed the data|participated in preparing and writing the manuscript|performed the analysis with constructive discussions	performed the experiments	Performed the experiments	Investigation	YES
5572355	28878799	AA	PLoS52	performed the experiments|analyzed the data|participated in preparing and writing the manuscript|performed the analysis with constructive discussions	analyzed the data	Analyzed the data	Formal analysis	YES
5572355	28878799	AA	PLoS52	performed the experiments|analyzed the data|participated in preparing and writing the manuscript|performed the analysis with constructive discussions	participated in preparing and writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5572355	28878799	AA	PLoS52	performed the experiments|analyzed the data|participated in preparing and writing the manuscript|performed the analysis with constructive discussions	performed the analysis with constructive discussions	Performed the experiments	Investigation	YES
5572355	28878799	All authors	PLoS52	contributed to revising the manuscript	contributed to revising the manuscript	Wrote the paper	Writing - Review & Editing	YES
5572355	28878799	IK	PLoS52	analyzed the data|participated in preparing and writing the manuscript|performed the analysis with constructive discussions	analyzed the data	Analyzed the data	Formal analysis	YES
5572355	28878799	IK	PLoS52	analyzed the data|participated in preparing and writing the manuscript|performed the analysis with constructive discussions	participated in preparing and writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5572355	28878799	IK	PLoS52	analyzed the data|participated in preparing and writing the manuscript|performed the analysis with constructive discussions	performed the analysis with constructive discussions	Performed the experiments	Investigation	YES
5572355	28878799	MB	PLoS52	performed the experiments|analyzed the data|participated in preparing and writing the manuscript|performed the analysis with constructive discussions	performed the experiments	Performed the experiments	Investigation	YES
5572355	28878799	MB	PLoS52	performed the experiments|analyzed the data|participated in preparing and writing the manuscript|performed the analysis with constructive discussions	analyzed the data	Analyzed the data	Formal analysis	YES
5572355	28878799	MB	PLoS52	performed the experiments|analyzed the data|participated in preparing and writing the manuscript|performed the analysis with constructive discussions	participated in preparing and writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5572355	28878799	MB	PLoS52	performed the experiments|analyzed the data|participated in preparing and writing the manuscript|performed the analysis with constructive discussions	performed the analysis with constructive discussions	Performed the experiments	Investigation	YES
5572355	28878799	NB	PLoS52	performed the experiments|analyzed the data|participated in preparing and writing the manuscript|performed the analysis with constructive discussions	performed the experiments	Performed the experiments	Investigation	YES
5572355	28878799	NB	PLoS52	performed the experiments|analyzed the data|participated in preparing and writing the manuscript|performed the analysis with constructive discussions	analyzed the data	Analyzed the data	Formal analysis	YES
5572355	28878799	NB	PLoS52	performed the experiments|analyzed the data|participated in preparing and writing the manuscript|performed the analysis with constructive discussions	participated in preparing and writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5572355	28878799	NB	PLoS52	performed the experiments|analyzed the data|participated in preparing and writing the manuscript|performed the analysis with constructive discussions	performed the analysis with constructive discussions	Performed the experiments	Investigation	YES
5572355	28878799	OM	PLoS52	analyzed the data|participated in preparing and writing the manuscript|performed the analysis with constructive discussions	analyzed the data	Analyzed the data	Formal analysis	YES
5572355	28878799	OM	PLoS52	analyzed the data|participated in preparing and writing the manuscript|performed the analysis with constructive discussions	participated in preparing and writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5572355	28878799	OM	PLoS52	analyzed the data|participated in preparing and writing the manuscript|performed the analysis with constructive discussions	performed the analysis with constructive discussions	Performed the experiments	Investigation	YES
5572355	28878799	OR	PLoS52	performed the experiments|analyzed the data|participated in preparing and writing the manuscript|performed the analysis with constructive discussions	performed the experiments	Performed the experiments	Investigation	YES
5572355	28878799	OR	PLoS52	performed the experiments|analyzed the data|participated in preparing and writing the manuscript|performed the analysis with constructive discussions	analyzed the data	Analyzed the data	Formal analysis	YES
5572355	28878799	OR	PLoS52	performed the experiments|analyzed the data|participated in preparing and writing the manuscript|performed the analysis with constructive discussions	participated in preparing and writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5572355	28878799	OR	PLoS52	performed the experiments|analyzed the data|participated in preparing and writing the manuscript|performed the analysis with constructive discussions	performed the analysis with constructive discussions	Performed the experiments	Investigation	YES
5572355	28878799	OY	PLoS52	performed the experiments|analyzed the data|participated in preparing and writing the manuscript|performed the analysis with constructive discussions	performed the experiments	Performed the experiments	Investigation	YES
5572355	28878799	OY	PLoS52	performed the experiments|analyzed the data|participated in preparing and writing the manuscript|performed the analysis with constructive discussions	analyzed the data	Analyzed the data	Formal analysis	YES
5572355	28878799	OY	PLoS52	performed the experiments|analyzed the data|participated in preparing and writing the manuscript|performed the analysis with constructive discussions	participated in preparing and writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5572355	28878799	OY	PLoS52	performed the experiments|analyzed the data|participated in preparing and writing the manuscript|performed the analysis with constructive discussions	performed the analysis with constructive discussions	Performed the experiments	Investigation	YES
5572355	28878799	SZ	PLoS52	performed the experiments|analyzed the data|participated in preparing and writing the manuscript|performed the analysis with constructive discussions	performed the experiments	Performed the experiments	Investigation	YES
5572355	28878799	SZ	PLoS52	performed the experiments|analyzed the data|participated in preparing and writing the manuscript|performed the analysis with constructive discussions	analyzed the data	Analyzed the data	Formal analysis	YES
5572355	28878799	SZ	PLoS52	performed the experiments|analyzed the data|participated in preparing and writing the manuscript|performed the analysis with constructive discussions	participated in preparing and writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5572355	28878799	SZ	PLoS52	performed the experiments|analyzed the data|participated in preparing and writing the manuscript|performed the analysis with constructive discussions	performed the analysis with constructive discussions	Performed the experiments	Investigation	YES
5572355	28878799	TS	PLoS52	performed the experiments|analyzed the data|participated in preparing and writing the manuscript|performed the analysis with constructive discussions	performed the experiments	Performed the experiments	Investigation	YES
5572355	28878799	TS	PLoS52	performed the experiments|analyzed the data|participated in preparing and writing the manuscript|performed the analysis with constructive discussions	analyzed the data	Analyzed the data	Formal analysis	YES
5572355	28878799	TS	PLoS52	performed the experiments|analyzed the data|participated in preparing and writing the manuscript|performed the analysis with constructive discussions	participated in preparing and writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5572355	28878799	TS	PLoS52	performed the experiments|analyzed the data|participated in preparing and writing the manuscript|performed the analysis with constructive discussions	performed the analysis with constructive discussions	Performed the experiments	Investigation	YES
5572355	28878799	VL	PLoS52	analyzed the data|participated in preparing and writing the manuscript|performed the analysis with constructive discussions	analyzed the data	Analyzed the data	Formal analysis	YES
5572355	28878799	VL	PLoS52	analyzed the data|participated in preparing and writing the manuscript|performed the analysis with constructive discussions	participated in preparing and writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5572355	28878799	VL	PLoS52	analyzed the data|participated in preparing and writing the manuscript|performed the analysis with constructive discussions	performed the analysis with constructive discussions	Performed the experiments	Investigation	YES
5572355	28878799	ZG	PLoS52	performed the experiments|analyzed the data|participated in preparing and writing the manuscript|performed the analysis with constructive discussions	performed the experiments	Performed the experiments	Investigation	YES
5572355	28878799	ZG	PLoS52	performed the experiments|analyzed the data|participated in preparing and writing the manuscript|performed the analysis with constructive discussions	analyzed the data	Analyzed the data	Formal analysis	YES
5572355	28878799	ZG	PLoS52	performed the experiments|analyzed the data|participated in preparing and writing the manuscript|performed the analysis with constructive discussions	participated in preparing and writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5572355	28878799	ZG	PLoS52	performed the experiments|analyzed the data|participated in preparing and writing the manuscript|performed the analysis with constructive discussions	performed the analysis with constructive discussions	Performed the experiments	Investigation	YES
5333385	28249567	DY-H	PLoS52	participating in modifying the final version	participating in modifying the final version	-	-	NO
5333385	28249567	JW	PLoS52	participating in modifying the final version	participating in modifying the final version	-	-	NO
5333385	28249567	MH	PLoS52	performed the qpcr assay of the sex pheromone biosynthesis genes and analysed the data	performed the qpcr assay of the sex pheromone biosynthesis genes and analysed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5333385	28249567	PH	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5333385	28249567	WM-X	PLoS52	performed the qpcr assay of the sex pheromone biosynthesis genes and analysed the data|participating in modifying the final version	performed the qpcr assay of the sex pheromone biosynthesis genes and analysed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5333385	28249567	WM-X	PLoS52	performed the qpcr assay of the sex pheromone biosynthesis genes and analysed the data|participating in modifying the final version	participating in modifying the final version	-	-	NO
5333385	28249567	XF-T	PLoS52	performed the qpcr assay of the sex pheromone biosynthesis genes and analysed the data	performed the qpcr assay of the sex pheromone biosynthesis genes and analysed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5333385	28249567	YF-Z	PLoS52	participating in modifying the final version	participating in modifying the final version	-	-	NO
6282912	30524167	All the authors	2	were involved during the investigation process in all stages of this study including a primary data collection, analysis and the documentation of the collection	were involved during the investigation process in all stages of this study including a primary data collection, analysis and the documentation of the collection	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
6016321	29946454	Ashur Y. Oraha	7	surgeons performing the operation. Final approval of the manuscript	surgeons performing the operation. Final approval of the manuscript	Performed the experiments	Investigation	YES
6016321	29946454	Darya A. Faqe	7	surgeons performing the operation. Final approval of the manuscript	surgeons performing the operation. Final approval of the manuscript	Performed the experiments	Investigation	YES
6016321	29946454	Fahmi H. Kakamad	7	drafting the manuscript, collecting the data, final approval of the manuscript	drafting the manuscript, collecting the data, final approval of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6016321	29946454	Fitoon F. Yaldo	7	drafting the manuscript, collecting the data, final approval of the manuscript	drafting the manuscript, collecting the data, final approval of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6016321	29946454	Mahmood Kadoura	7	surgeons performing the operation. Final approval of the manuscript	surgeons performing the operation. Final approval of the manuscript	Performed the experiments	Investigation	YES
6016321	29946454	Sabah Qadir Aziz	7	drafting the manuscript, collecting the data, final approval of the manuscript	drafting the manuscript, collecting the data, final approval of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4975735	27495913	AM	2	made substantial contribution to the analysis of the data	made substantial contribution to the analysis of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
4975735	27495913	FS	2	conceived the study and participated in its design and coordination	conceived the study and participated in its design and coordination	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
4975735	27495913	JB	2	made substantial contribution to the acquisition of the data	made substantial contribution to the acquisition of the data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4975735	27495913	LB	2	has been involved in drafting the manuscript and revising it critically, before giving final approval to be submitted	has been involved in drafting the manuscript and revising it critically, before giving final approval to be submitted	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4975735	27495913	PP	2	participated in the design of the study and performed the statistical analysis	participated in the design of the study and performed the statistical analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
4975735	27495913	SM	2	made substantial contribution to the design of the study and coordination	made substantial contribution to the design of the study and coordination	Conceived and designed the experiments	Methodology|Project administration	YES
4406679	25901572	AKB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406679	25901572	AKB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406679	25901572	AKB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406679	25901572	AKB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406679	25901572	AKB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406679	25901572	AMS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406679	25901572	AMS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406679	25901572	AMS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406679	25901572	GC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4406679	25901572	GC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406679	25901572	LLM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406679	25901572	LLM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406679	25901572	LLM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406679	25901572	LTCG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406679	25901572	LTCG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4406679	25901572	LTCG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4406679	25901572	LTCG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406679	25901572	RVJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406679	25901572	RVJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406679	25901572	RVJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406679	25901572	RVJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406679	25901572	TM	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406679	25901572	TM	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5333405	28249563	Both authors	PLoS52	designed the experiments, analyzed the results, and wrote the manuscript	designed the experiments, analyzed the results, and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5333405	28249563	KEG	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
6016322	29946452	Hoong-Yin Chong	2	performed the data collection	performed the data collection	Performed the experiments	Investigation	YES
6016322	29946452	Hyung-Ho Kim	2	performed the data collection	performed the data collection	Performed the experiments	Investigation	YES
6016322	29946452	Jongwon Kim	2	performed the data collection	performed the data collection	Performed the experiments	Investigation	YES
6016322	29946452	Moritz Wente	2	designed the study|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
6016322	29946452	Moritz Wente	2	designed the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6016322	29946452	Petra Baumann	2	designed the study|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
6016322	29946452	Petra Baumann	2	designed the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6016322	29946452	Sang-Hoon Ahn	2	performed the data collection	performed the data collection	Performed the experiments	Investigation	YES
6016322	29946452	Viktor Breul	2	was responsible for data analysis	was responsible for data analysis	Analyzed the data	Formal analysis	YES
5572363	28878789	AND	2	set up the experimental design, analyzed the data, and wrote the initial manuscript	set up the experimental design, analyzed the data, and wrote the initial manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5572363	28878789	CP	2	provided all resources including funding, designed the experiment and edited the manuscript	provided all resources including funding, designed the experiment and edited the manuscript	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Funding acquisition|Methodology|Resources|Writing - Review & Editing	YES
5572363	28878789	DF	2	created the mapping populations and edited the manuscript	created the mapping populations and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5572363	28878789	JH	2	edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5572363	28878789	KA	2	created the mapping populations and edited the manuscript	created the mapping populations and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
1929115	17608936	TJP	2	was responsible for the entire manuscript	was responsible for the entire manuscript	-	-	NO
1934374	17608933	OD	2	carried out the analysis of the clinical cases, and the discussion	carried out the analysis of the clinical cases, and the discussion	Performed the experiments	Investigation	YES
1934374	17608933	OV	2	was invited to participate, as specialist in ancient philosophy and literature	was invited to participate, as specialist in ancient philosophy and literature	-	-	NO
4406680	25902148	BT	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406680	25902148	CN	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406680	25902148	DE	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406680	25902148	DE	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406680	25902148	DE	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406680	25902148	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406680	25902148	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406680	25902148	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406680	25902148	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1936426	17603873	ARK	2	prepared the analysis of the literary texts	prepared the analysis of the literary texts	-	-	NO
1936426	17603873	MHK	2	wrote the sections on the theoretical background of the lived and the living body and drafted the manuscript	wrote the sections on the theoretical background of the lived and the living body and drafted the manuscript	Wrote the paper	Formal analysis|Writing - Original Draft	YES
4998199	27526050	HF	2	carried out the manuscript editing and the statistical analysis	carried out the manuscript editing and the statistical analysis	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
4998199	27526050	MM	2	carried out the data management	carried out the data management	Analyzed the data	Data curation	YES
4998199	27526050	TA	2	carried out the data management	carried out the data management	Analyzed the data	Data curation	YES
4998199	27526050	TH	2	carried out the experimental studies, data collection and drafted the manuscript|carried out the computer programming and the statistical analysis	carried out the experimental studies, data collection and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4998199	27526050	TH	2	carried out the experimental studies, data collection and drafted the manuscript|carried out the computer programming and the statistical analysis	carried out the computer programming and the statistical analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Software	YES
4998199	27526050	TI	2	carried out the experimental studies, data collection and drafted the manuscript|carried out the calibration of the well counters	carried out the experimental studies, data collection and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4998199	27526050	TI	2	carried out the experimental studies, data collection and drafted the manuscript|carried out the calibration of the well counters	carried out the calibration of the well counters	Performed the experiments	Investigation	YES
4998199	27526050	TK	2	carried out the device management and the configuration	carried out the device management and the configuration	Performed the experiments	Investigation	YES
5333453	28249560	HL	2	performed the field cultivation of cotton plants and ovules collection	performed the field cultivation of cotton plants and ovules collection	Performed the experiments	Investigation	YES
5333453	28249560	JM	2	performed the sscp experiments	performed the sscp experiments	Performed the experiments	Investigation	YES
5333453	28249560	JY	2	directed the experiments	directed the experiments	-	Supervision	YES
5333453	28249560	JZ	2	conceived the study and revised the manuscript|wrote the manuscript	conceived the study and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5333453	28249560	JZ	2	conceived the study and revised the manuscript|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5333453	28249560	MW	2	participated in the study	participated in the study	-	-	NO
5333453	28249560	NW	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5333453	28249560	SY	2	directed the experiments	directed the experiments	-	Supervision	YES
5333453	28249560	WP	2	performed the field cultivation of cotton plants and ovules collection	performed the field cultivation of cotton plants and ovules collection	Performed the experiments	Investigation	YES
5333453	28249560	XL	2	performed the field cultivation of cotton plants and ovules collection	performed the field cultivation of cotton plants and ovules collection	Performed the experiments	Investigation	YES
6282914	30524169	Each author	2	gave substantial contributions to the conception or design of the work in acquisition, analysis, or interpretation of data for the work|had a part in article preparing for drafting or revising it critically for important intellectual content, and all authors gave final approval of the version to be published and agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	gave substantial contributions to the conception or design of the work in acquisition, analysis, or interpretation of data for the work	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
6282914	30524169	Each author	2	gave substantial contributions to the conception or design of the work in acquisition, analysis, or interpretation of data for the work|had a part in article preparing for drafting or revising it critically for important intellectual content, and all authors gave final approval of the version to be published and agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	had a part in article preparing for drafting or revising it critically for important intellectual content, and all authors gave final approval of the version to be published and agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5572371	28878801	AA-K	2	helped to finalize the final draft of the manuscript	helped to finalize the final draft of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5572371	28878801	MK	2	helped to write first draft of the manuscript	helped to write first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
5572371	28878801	MS	2	conceived the idea, produced the first draft of the manuscript, and helped to draw the figures|participated to retrieve the data and helped to prepare first draft of the manuscript	conceived the idea, produced the first draft of the manuscript, and helped to draw the figures	Conceived and designed the experiments|Wrote the paper	Conceptualization|Visualization|Writing - Original Draft	YES
5572371	28878801	MS	2	conceived the idea, produced the first draft of the manuscript, and helped to draw the figures|participated to retrieve the data and helped to prepare first draft of the manuscript	participated to retrieve the data and helped to prepare first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
5572371	28878801	MT	2	helped to formulate all the tables	helped to formulate all the tables	Conceived and designed the experiments	Conceptualization	YES
5572371	28878801	SA-K	2	helped to finalize the final draft of the manuscript	helped to finalize the final draft of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5572371	28878801	ZI	2	collected the data, helped to draw the figures, and participated to produce the first draft of the manuscript	collected the data, helped to draw the figures, and participated to produce the first draft of the manuscript	Performed the experiments|Wrote the paper	Investigation|Visualization|Writing - Original Draft	YES
6016440	29946458	Alberto Raposo	1	Design|Writing first draft of manuscript	Design	Conceived and designed the experiments	-	YES
6016440	29946458	Alberto Raposo	1	Design|Writing first draft of manuscript	Writing first draft of manuscript	Wrote the paper	Writing - Original Draft	YES
6016440	29946458	Alfonso Marco	1	Collection	Collection	-	-	NO
6016440	29946458	All	1	Critical review and approval of manuscript	Critical review and approval of manuscript	Wrote the paper	Writing - Review & Editing	YES
6016440	29946458	Maria E. Garcia-Solano	1	Writing first draft of manuscript	Writing first draft of manuscript	Wrote the paper	Writing - Original Draft	YES
6282915	30524173	I.M.	2	gave substantial contributions to the conception or design of the work in acquisition, analysis, or interpretation of data for the workand gave final approval of the version to be published and agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	gave substantial contributions to the conception or design of the work in acquisition, analysis, or interpretation of data for the workand gave final approval of the version to be published and agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Data curation|Formal analysis|Investigation|Resources	YES
4406681	25901602	ALC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406681	25901602	ALC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406681	25901602	ALC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406681	25901602	ALC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406681	25901602	ALC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406681	25901602	NT	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406681	25901602	NT	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406681	25901602	NT	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406681	25901602	PT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406681	25901602	PT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406681	25901602	PT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406681	25901602	PT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406681	25901602	PT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4999387	27562024	BW	2	made substantial contributions to this work, actively participating in the preparation and review of the manuscript	made substantial contributions to this work, actively participating in the preparation and review of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4999387	27562024	CEST	2	expertise and collaborated in the review of the pertinence and accuracy of its contents	expertise and collaborated in the review of the pertinence and accuracy of its contents	-	-	NO
4999387	27562024	GD	2	made substantial contributions to this work, actively participating in the preparation and review of the manuscript	made substantial contributions to this work, actively participating in the preparation and review of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4999387	27562024	GW	2	made substantial contributions to this work, actively participating in the preparation and review of the manuscript	made substantial contributions to this work, actively participating in the preparation and review of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4999387	27562024	MZ	2	made substantial contributions to this work, actively participating in the preparation and review of the manuscript	made substantial contributions to this work, actively participating in the preparation and review of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4508378	26236717	Juan M. Adrian-Segarra	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
4508378	26236717	Manfred Richter	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
4508378	26236717	Yunlong Hou	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
5081489	27784509	AZP	2	conducted data analysis|contributed to writing and critical review of the manuscript	conducted data analysis	Analyzed the data	Formal analysis	YES
5081489	27784509	AZP	2	conducted data analysis|contributed to writing and critical review of the manuscript	contributed to writing and critical review of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5081489	27784509	BY	2	contributed to writing and critical review of the manuscript	contributed to writing and critical review of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5081489	27784509	CJH	2	contributed to writing and critical review of the manuscript	contributed to writing and critical review of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5081489	27784509	GM	2	drafted and revised the manuscript|conducted data analysis	drafted and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5081489	27784509	GM	2	drafted and revised the manuscript|conducted data analysis	conducted data analysis	Analyzed the data	Formal analysis	YES
5081489	27784509	KHT	2	contributed to writing and critical review of the manuscript	contributed to writing and critical review of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5081489	27784509	MR	2	conducted data analysis	conducted data analysis	Analyzed the data	Formal analysis	YES
5081489	27784509	NNM	2	contributed to writing and critical review of the manuscript	contributed to writing and critical review of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5081489	27784509	SN	2	contributed to writing and critical review of the manuscript	contributed to writing and critical review of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5081489	27784509	WD	2	conducted data analysis|contributed to writing and critical review of the manuscript	conducted data analysis	Analyzed the data	Formal analysis	YES
5081489	27784509	WD	2	conducted data analysis|contributed to writing and critical review of the manuscript	contributed to writing and critical review of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5335751	28253862	CAB	2	designed the experiments|prepared the manuscript|read, commented and approved the final manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5335751	28253862	CAB	2	designed the experiments|prepared the manuscript|read, commented and approved the final manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5335751	28253862	CAB	2	designed the experiments|prepared the manuscript|read, commented and approved the final manuscript	read, commented and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5335751	28253862	FG	2	designed the experiments|prepared the manuscript|read, commented and approved the final manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5335751	28253862	FG	2	designed the experiments|prepared the manuscript|read, commented and approved the final manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5335751	28253862	FG	2	designed the experiments|prepared the manuscript|read, commented and approved the final manuscript	read, commented and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5335751	28253862	MT	2	designed the experiments|helped sck carried out the molecular work and most bioinformatics analyses with|prepared the manuscript|read, commented and approved the final manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5335751	28253862	MT	2	designed the experiments|helped sck carried out the molecular work and most bioinformatics analyses with|prepared the manuscript|read, commented and approved the final manuscript	helped sck carried out the molecular work and most bioinformatics analyses with	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5335751	28253862	MT	2	designed the experiments|helped sck carried out the molecular work and most bioinformatics analyses with|prepared the manuscript|read, commented and approved the final manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5335751	28253862	MT	2	designed the experiments|helped sck carried out the molecular work and most bioinformatics analyses with|prepared the manuscript|read, commented and approved the final manuscript	read, commented and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5335751	28253862	SCK	2	designed the experiments|carried out the molecular work and most bioinformatics analyses with|prepared the manuscript|read, commented and approved the final manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5335751	28253862	SCK	2	designed the experiments|carried out the molecular work and most bioinformatics analyses with|prepared the manuscript|read, commented and approved the final manuscript	carried out the molecular work and most bioinformatics analyses with	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5335751	28253862	SCK	2	designed the experiments|carried out the molecular work and most bioinformatics analyses with|prepared the manuscript|read, commented and approved the final manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5335751	28253862	SCK	2	designed the experiments|carried out the molecular work and most bioinformatics analyses with|prepared the manuscript|read, commented and approved the final manuscript	read, commented and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5572373	28878804	B-SZ	2	carried out all the experiments and data analysis	carried out all the experiments and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5572373	28878804	C-ZY	2	carried out all the experiments and data analysis	carried out all the experiments and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5572373	28878804	H-NZ	2	carried out all the experiments and data analysis	carried out all the experiments and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5572373	28878804	S-SY	2	carried out all the experiments and data analysis	carried out all the experiments and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5572373	28878804	SL	2	carried out all the experiments and data analysis	carried out all the experiments and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5572373	28878804	X-LJ	2	supervised the analysis and critically revised the manuscript	supervised the analysis and critically revised the manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
5572373	28878804	Y-NZ	2	carried out all the experiments and data analysis	carried out all the experiments and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5572373	28878804	Y-PG	2	conceived the project, designed the experiments and drafted the manuscript	conceived the project, designed the experiments and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
2001294	17850664	JLM	2	attest they have made substantial contributions in drafting the manuscript and revising it critically for important intellectual content|read and approved the final manuscript	attest they have made substantial contributions in drafting the manuscript and revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
2001294	17850664	JLM	2	attest they have made substantial contributions in drafting the manuscript and revising it critically for important intellectual content|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
2001294	17850664	JLV	2	attest they have made substantial contributions in drafting the manuscript and revising it critically for important intellectual content|read and approved the final manuscript	attest they have made substantial contributions in drafting the manuscript and revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
2001294	17850664	JLV	2	attest they have made substantial contributions in drafting the manuscript and revising it critically for important intellectual content|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
2001294	17850664	MYR	2	attest they have made substantial contributions in drafting the manuscript and revising it critically for important intellectual content|read and approved the final manuscript	attest they have made substantial contributions in drafting the manuscript and revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
2001294	17850664	MYR	2	attest they have made substantial contributions in drafting the manuscript and revising it critically for important intellectual content|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6282916	30524168	Each author	2	gave substantial contributions to the conception or design of the work in acquisition, analysis, or interpretation of data for the work|had a part in article preparing for drafting or revising it critically for important intellectual content, and all authors gave final approval of the version to be published and agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	gave substantial contributions to the conception or design of the work in acquisition, analysis, or interpretation of data for the work	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
6282916	30524168	Each author	2	gave substantial contributions to the conception or design of the work in acquisition, analysis, or interpretation of data for the work|had a part in article preparing for drafting or revising it critically for important intellectual content, and all authors gave final approval of the version to be published and agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	had a part in article preparing for drafting or revising it critically for important intellectual content, and all authors gave final approval of the version to be published and agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4677188	26697227	All authors	PLoS52	contributed in preparing the paper	contributed in preparing the paper	-	-	NO
4677188	26697227	Farid Ahmed	PLoS52	provided clinical and critical appraisal	provided clinical and critical appraisal	-	-	NO
4677188	26697227	Giles Cunnick	PLoS52	provided clinical and critical appraisal	provided clinical and critical appraisal	-	-	NO
4677188	26697227	Gurdeep S. Mannu	PLoS52	conceived the study and collected the baseline data|collated the data and prepared the draft paper|contributed equally	conceived the study and collected the baseline data	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
4677188	26697227	Gurdeep S. Mannu	PLoS52	conceived the study and collected the baseline data|collated the data and prepared the draft paper|contributed equally	collated the data and prepared the draft paper	Analyzed the data|Wrote the paper	Data curation|Writing - Original Draft	YES
4677188	26697227	Gurdeep S. Mannu	PLoS52	conceived the study and collected the baseline data|collated the data and prepared the draft paper|contributed equally	contributed equally	-	-	NO
4677188	26697227	Joao H. Bettencourt-Silva	PLoS52	collated the data and prepared the draft paper|analysed the data|contributed equally	collated the data and prepared the draft paper	Analyzed the data|Wrote the paper	Data curation|Writing - Original Draft	YES
4677188	26697227	Joao H. Bettencourt-Silva	PLoS52	collated the data and prepared the draft paper|analysed the data|contributed equally	analysed the data	Analyzed the data	Formal analysis	YES
4677188	26697227	Joao H. Bettencourt-Silva	PLoS52	collated the data and prepared the draft paper|analysed the data|contributed equally	contributed equally	-	-	NO
5005238	27576333	All authors	2	were responsible for the study concepts/study design, data acquisition, or data analysis/interpretation|were responsible for the manuscript drafting or manuscript revision for important intellectual content|were responsible for the approval of the final version of the submitted manuscript|agreed to ensure any questions related to the work are appropriately resolved|were responsible for the manuscript editing	were responsible for the study concepts/study design, data acquisition, or data analysis/interpretation	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation|Methodology	YES
5005238	27576333	All authors	2	were responsible for the study concepts/study design, data acquisition, or data analysis/interpretation|were responsible for the manuscript drafting or manuscript revision for important intellectual content|were responsible for the approval of the final version of the submitted manuscript|agreed to ensure any questions related to the work are appropriately resolved|were responsible for the manuscript editing	were responsible for the manuscript drafting or manuscript revision for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5005238	27576333	All authors	2	were responsible for the study concepts/study design, data acquisition, or data analysis/interpretation|were responsible for the manuscript drafting or manuscript revision for important intellectual content|were responsible for the approval of the final version of the submitted manuscript|agreed to ensure any questions related to the work are appropriately resolved|were responsible for the manuscript editing	were responsible for the approval of the final version of the submitted manuscript	-	-	NO
5005238	27576333	All authors	2	were responsible for the study concepts/study design, data acquisition, or data analysis/interpretation|were responsible for the manuscript drafting or manuscript revision for important intellectual content|were responsible for the approval of the final version of the submitted manuscript|agreed to ensure any questions related to the work are appropriately resolved|were responsible for the manuscript editing	agreed to ensure any questions related to the work are appropriately resolved	-	-	NO
5005238	27576333	All authors	2	were responsible for the study concepts/study design, data acquisition, or data analysis/interpretation|were responsible for the manuscript drafting or manuscript revision for important intellectual content|were responsible for the approval of the final version of the submitted manuscript|agreed to ensure any questions related to the work are appropriately resolved|were responsible for the manuscript editing	were responsible for the manuscript editing	Wrote the paper	Writing - Review & Editing	YES
5005238	27576333	CB	2	were the guarantors of the integrity of the entire study|were responsible for the literature research|were responsible for the experimental studies	were the guarantors of the integrity of the entire study	-	-	NO
5005238	27576333	CB	2	were the guarantors of the integrity of the entire study|were responsible for the literature research|were responsible for the experimental studies	were responsible for the literature research	-	Formal analysis	YES
5005238	27576333	CB	2	were the guarantors of the integrity of the entire study|were responsible for the literature research|were responsible for the experimental studies	were responsible for the experimental studies	Performed the experiments	Investigation	YES
5005238	27576333	HWAMdJ	2	were the guarantors of the integrity of the entire study|were responsible for the literature research|were responsible for the experimental studies	were the guarantors of the integrity of the entire study	-	-	NO
5005238	27576333	HWAMdJ	2	were the guarantors of the integrity of the entire study|were responsible for the literature research|were responsible for the experimental studies	were responsible for the literature research	-	Formal analysis	YES
5005238	27576333	HWAMdJ	2	were the guarantors of the integrity of the entire study|were responsible for the literature research|were responsible for the experimental studies	were responsible for the experimental studies	Performed the experiments	Investigation	YES
5005238	27576333	ME	2	were responsible for the experimental studies	were responsible for the experimental studies	Performed the experiments	Investigation	YES
4406682	25902074	AB	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406682	25902074	AN	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406682	25902074	CM	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4406682	25902074	CM	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4406682	25902074	HB	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4406682	25902074	HB	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4406682	25902074	IS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406682	25902074	IS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4406682	25902074	IS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4406682	25902074	JC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406682	25902074	JC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406682	25902074	JC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406682	25902074	KAE	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406682	25902074	KF	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4406682	25902074	KF	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406682	25902074	MK	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406682	25902074	PJGMW	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406682	25902074	PJGMW	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406682	25902074	PVH	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4406682	25902074	PVH	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4406682	25902074	RM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406682	25902074	RM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4406682	25902074	RM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4406682	25902074	YI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406682	25902074	YI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406682	25902074	YI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406682	25902074	YI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406682	25902074	YI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5087211	27797320	ADC	2	has made substantial contributions to study design, analysis and interpretation of data, served as overall dc cohort study principal investigator and has been involved in drafting the manuscript and revising it critically	has made substantial contributions to study design, analysis and interpretation of data, served as overall dc cohort study principal investigator and has been involved in drafting the manuscript and revising it critically	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Funding acquisition|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5087211	27797320	AW	2	contributed to study design, collected the data and participated in the interpretation of data, and has been involved in revising manuscript critically	contributed to study design, collected the data and participated in the interpretation of data, and has been involved in revising manuscript critically	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Review & Editing	YES
5087211	27797320	All authors	2	listed on submitted manuscripts have read and agreed to its content, and meet the authorship requirements as detailed below|have given final approval of the version to be published	listed on submitted manuscripts have read and agreed to its content, and meet the authorship requirements as detailed below	-	-	NO
5087211	27797320	All authors	2	listed on submitted manuscripts have read and agreed to its content, and meet the authorship requirements as detailed below|have given final approval of the version to be published	have given final approval of the version to be published	-	-	NO
5087211	27797320	HAY	2	has analyzed and interpreted the data and has been involved in drafting the manuscript and revising it critically for data analysis and interpretation	has analyzed and interpreted the data and has been involved in drafting the manuscript and revising it critically for data analysis and interpretation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5087211	27797320	JH	2	has made substantial contributions to study design, collected the data, participated in the analysis and interpretation of data, and has been involved in drafting the manuscript and revising it critically	has made substantial contributions to study design, collected the data, participated in the analysis and interpretation of data, and has been involved in drafting the manuscript and revising it critically	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5087211	27797320	KSL	2	made substantial contributions to conception and design, collected the data, participated in the analysis and interpretation of data, and has been involved in drafting the manuscript and revising it critically	made substantial contributions to conception and design, collected the data, participated in the analysis and interpretation of data, and has been involved in drafting the manuscript and revising it critically	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5087211	27797320	NR	2	developed the conception and design, served as a site principal investigator, led acquisition of data, analysis and interpretation of data, and drafted and critically revised the manuscript	developed the conception and design, served as a site principal investigator, led acquisition of data, analysis and interpretation of data, and drafted and critically revised the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Funding acquisition|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
6019686	30013771	All authors	2	participated in patient care	participated in patient care	Performed the experiments	Investigation	YES
6019686	30013771	EM	2	wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
6019686	30013771	YS	2	wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
6282917	30524161	A.H.	2	gave substantial contributions to the conception or design of the work in acquisition, analysis, or interpretation of data for the work|had a part in article preparing for drafting or revising it critically for important intellectual content, and all authors gave final approval of the version to be published and agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	gave substantial contributions to the conception or design of the work in acquisition, analysis, or interpretation of data for the work	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
6282917	30524161	A.H.	2	gave substantial contributions to the conception or design of the work in acquisition, analysis, or interpretation of data for the work|had a part in article preparing for drafting or revising it critically for important intellectual content, and all authors gave final approval of the version to be published and agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	had a part in article preparing for drafting or revising it critically for important intellectual content, and all authors gave final approval of the version to be published and agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6282917	30524161	R.D.	2	gave substantial contributions to the conception or design of the work in acquisition, analysis, or interpretation of data for the work	gave substantial contributions to the conception or design of the work in acquisition, analysis, or interpretation of data for the work	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
6282917	30524161	S.S.	2	gave substantial contributions to the conception or design of the work in acquisition, analysis, or interpretation of data for the work	gave substantial contributions to the conception or design of the work in acquisition, analysis, or interpretation of data for the work	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
6282917	30524161	T.Q.	2	had a part in article preparing for drafting or revising it critically for important intellectual content, and all authors gave final approval of the version to be published and agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	had a part in article preparing for drafting or revising it critically for important intellectual content, and all authors gave final approval of the version to be published and agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5572379	28878796	DW	2	analyzed the data and drafted the manuscript	analyzed the data and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5572379	28878796	JF	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5572379	28878796	JS	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5572379	28878796	JZ	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5572379	28878796	LL	2	conceived and designed the study|analyzed the data and drafted the manuscript|carried out the experiments	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5572379	28878796	LL	2	conceived and designed the study|analyzed the data and drafted the manuscript|carried out the experiments	analyzed the data and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5572379	28878796	LL	2	conceived and designed the study|analyzed the data and drafted the manuscript|carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5572379	28878796	PZ	2	conceived and designed the study|analyzed the data and drafted the manuscript|carried out the experiments	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5572379	28878796	PZ	2	conceived and designed the study|analyzed the data and drafted the manuscript|carried out the experiments	analyzed the data and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5572379	28878796	PZ	2	conceived and designed the study|analyzed the data and drafted the manuscript|carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5572379	28878796	QG	2	conceived and designed the study|analyzed the data and drafted the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5572379	28878796	QG	2	conceived and designed the study|analyzed the data and drafted the manuscript	analyzed the data and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5572379	28878796	RZ	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5572379	28878796	ZW	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5335773	28253861	CG	2	prepared the samples, performed the experiments, analyzed the data and wrote the original manuscript	prepared the samples, performed the experiments, analyzed the data and wrote the original manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5335773	28253861	CL	2	managed the plant materials	managed the plant materials	Performed the experiments	Investigation	YES
5335773	28253861	CZ	2	performed some experiments and took care of the plants	performed some experiments and took care of the plants	Performed the experiments	Investigation	YES
5335773	28253861	HX	2	performed some experiments and took care of the plants	performed some experiments and took care of the plants	Performed the experiments	Investigation	YES
5335773	28253861	LH	2	performed some experiments and took care of the plants	performed some experiments and took care of the plants	Performed the experiments	Investigation	YES
5335773	28253861	PW	2	prepared the samples, performed the experiments, analyzed the data and wrote the original manuscript	prepared the samples, performed the experiments, analyzed the data and wrote the original manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5335773	28253861	SZ	2	managed the plant materials	managed the plant materials	Performed the experiments	Investigation	YES
5335773	28253861	XW	2	conceived and designed the research	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5335773	28253861	YZ	2	performed some experiments and took care of the plants	performed some experiments and took care of the plants	Performed the experiments	Investigation	YES
5335773	28253861	ZJ	2	finalized the figures and tables	finalized the figures and tables	-	Visualization	YES
6019755	30023055	Luis Trevino-Gonzalez	2	research team coordinator, data collection and analysis, final approval	research team coordinator, data collection and analysis, final approval	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Project administration	YES
5031567	27654452	BW	2	contributed to the planning and the implementation of the study and also contributed to the manuscript writing	contributed to the planning and the implementation of the study and also contributed to the manuscript writing	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5031567	27654452	JH	2	contributed to the implementation of the study and did an important part of the dosimetry and contributed to the manuscript writing	contributed to the implementation of the study and did an important part of the dosimetry and contributed to the manuscript writing	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5031567	27654452	JS	2	planned and was responsible for the implementation of the study and was also main responsible for the manuscript writing	planned and was responsible for the implementation of the study and was also main responsible for the manuscript writing	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
5031567	27654452	LH	2	contributed to the implementation of the study and did a great part of the dosimetry and also contributed to the manuscript writing	contributed to the implementation of the study and did a great part of the dosimetry and also contributed to the manuscript writing	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5031567	27654452	PB	2	contributed greatly to the planning and implementation of the study, to the dosimetry and to the manuscript writing	contributed greatly to the planning and implementation of the study, to the dosimetry and to the manuscript writing	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5031567	27654452	TR	2	contributed to the implementation of the study, developed the segmantation tool used for dosimetry and also contributed to the manuscript writing	contributed to the implementation of the study, developed the segmantation tool used for dosimetry and also contributed to the manuscript writing	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Resources|Writing - Original Draft	YES
4406684	25902056	NKS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406684	25902056	SC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406684	25902056	SS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406684	25902056	SS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406684	25902056	SS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406684	25902056	SS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406684	25902056	TRS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406684	25902056	TRS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406684	25902056	TRS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6019758	30013769	Jawad Hasnaoui	7	writing the paper	writing the paper	Wrote the paper	Writing - Original Draft	YES
6019758	30013769	Khadija Salama	7	writing the paper	writing the paper	Wrote the paper	Writing - Original Draft	YES
6019758	30013769	Meryem Lahjaouj	7	writing the paper	writing the paper	Wrote the paper	Writing - Original Draft	YES
6019758	30013769	Mohamed Moutaa Tatari	7	Corresponding author writing the paper	Corresponding author writing the paper	Wrote the paper	Writing - Original Draft	YES
6019758	30013769	Mohammed Mahtar	7	correction of the paper	correction of the paper	Wrote the paper	Writing - Review & Editing	YES
6019758	30013769	Mohammed Roubal	7	correction of the paper	correction of the paper	Wrote the paper	Writing - Review & Editing	YES
6019758	30013769	Reda Abada	7	Correction of the paper	Correction of the paper	Wrote the paper	Writing - Review & Editing	YES
6019758	30013769	Said Anajar	7	writing the paper	writing the paper	Wrote the paper	Writing - Original Draft	YES
6019758	30013769	Sami Rouadi	7	Correction of the paper	Correction of the paper	Wrote the paper	Writing - Review & Editing	YES
5572394	28878782	GL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5572394	28878782	GL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5572394	28878782	GL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5572394	28878782	KS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5572394	28878782	KS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
5572394	28878782	KS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5572394	28878782	KS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6282919	30524165	Each author	2	participated in article preparing for drafting or revising it critically for important intellectual content, and gave final approval of the version to be published and agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	participated in article preparing for drafting or revising it critically for important intellectual content, and gave final approval of the version to be published and agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6282919	30524165	G.C.	2	gave substantial contribution to the conception or design of the work in acquisition, analysis, or interpretation of data for the work	gave substantial contribution to the conception or design of the work in acquisition, analysis, or interpretation of data for the work	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
6282919	30524165	V.A.	2	gave substantial contribution to the conception or design of the work in acquisition, analysis, or interpretation of data for the work	gave substantial contribution to the conception or design of the work in acquisition, analysis, or interpretation of data for the work	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
5040656	27682837	All authors	2	revised the manuscript and approved the final manuscript	revised the manuscript and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5040656	27682837	DK	2	designed the study and analysed the data|drafted the manuscript	designed the study and analysed the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5040656	27682837	DK	2	designed the study and analysed the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5040656	27682837	JvD	2	designed the study and analysed the data	designed the study and analysed the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5040656	27682837	JvO	2	designed the study and analysed the data	designed the study and analysed the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5338094	28264649	CA	PLoS5	Contributed reagents/material/analysis tools	Contributed reagents/material/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5338094	28264649	CB	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/material/analysis tools|Wrote the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5338094	28264649	CB	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/material/analysis tools|Wrote the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
5338094	28264649	CB	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/material/analysis tools|Wrote the manuscript	Contributed reagents/material/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5338094	28264649	CB	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/material/analysis tools|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5338094	28264649	CX	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5338094	28264649	DT	PLoS5	Conceived and designed the experiments|Contributed reagents/material/analysis tools|Wrote the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5338094	28264649	DT	PLoS5	Conceived and designed the experiments|Contributed reagents/material/analysis tools|Wrote the manuscript	Contributed reagents/material/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5338094	28264649	DT	PLoS5	Conceived and designed the experiments|Contributed reagents/material/analysis tools|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5338094	28264649	EM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5338094	28264649	OG	PLoS5	Performed the experiments|Contributed reagents/material/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
5338094	28264649	OG	PLoS5	Performed the experiments|Contributed reagents/material/analysis tools	Contributed reagents/material/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5338094	28264649	SK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5338094	28264649	YL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
6282920	30524172	A.C.	2	gave substantial contributions to the conception or design of the work in acquisition, analysis, or interpretation of data for the work	gave substantial contributions to the conception or design of the work in acquisition, analysis, or interpretation of data for the work	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
6282920	30524172	Dz.Lj	2	gave substantial contributions to the conception or design of the work in acquisition, analysis, or interpretation of data for the work	gave substantial contributions to the conception or design of the work in acquisition, analysis, or interpretation of data for the work	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
6282920	30524172	E.N.	2	gave substantial contributions to the conception or design of the work in acquisition, analysis, or interpretation of data for the work	gave substantial contributions to the conception or design of the work in acquisition, analysis, or interpretation of data for the work	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
6282920	30524172	Each author	2	had a part in article preparing for drafting or revising it critically for important intellectual content and gave final approval of the version to be published and agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	had a part in article preparing for drafting or revising it critically for important intellectual content and gave final approval of the version to be published and agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5090107	27802846	DJC	2	developed the data analysis plan and wrote the manuscript|collected clinical data and contributed to the introduction and methods of the manuscript	developed the data analysis plan and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5090107	27802846	DJC	2	developed the data analysis plan and wrote the manuscript|collected clinical data and contributed to the introduction and methods of the manuscript	collected clinical data and contributed to the introduction and methods of the manuscript	Performed the experiments	Investigation	YES
5090107	27802846	EK	2	collected clinical data and contributed to the introduction and methods of the manuscript	collected clinical data and contributed to the introduction and methods of the manuscript	Performed the experiments	Investigation	YES
5090107	27802846	JA	2	developed the data analysis plan and wrote the manuscript|developed the study protocol, supervised all aspects of the study implementation and contributed to the discussion section	developed the data analysis plan and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5090107	27802846	JA	2	developed the data analysis plan and wrote the manuscript|developed the study protocol, supervised all aspects of the study implementation and contributed to the discussion section	developed the study protocol, supervised all aspects of the study implementation and contributed to the discussion section	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Supervision	YES
5090107	27802846	JI	2	collected clinical data and contributed to the introduction and methods of the manuscript	collected clinical data and contributed to the introduction and methods of the manuscript	Performed the experiments	Investigation	YES
5090107	27802846	KB	2	collected clinical data and contributed to the introduction and methods of the manuscript	collected clinical data and contributed to the introduction and methods of the manuscript	Performed the experiments	Investigation	YES
5090107	27802846	MR	2	developed the study protocol, supervised all aspects of the study implementation and contributed to the discussion section	developed the study protocol, supervised all aspects of the study implementation and contributed to the discussion section	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Supervision	YES
5090107	27802846	NP	2	collected clinical data and contributed to the introduction and methods of the manuscript|developed the study protocol, supervised all aspects of the study implementation and contributed to the discussion section	collected clinical data and contributed to the introduction and methods of the manuscript	Performed the experiments	Investigation	YES
5090107	27802846	NP	2	collected clinical data and contributed to the introduction and methods of the manuscript|developed the study protocol, supervised all aspects of the study implementation and contributed to the discussion section	developed the study protocol, supervised all aspects of the study implementation and contributed to the discussion section	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Supervision	YES
5090107	27802846	PP	2	developed the study protocol, supervised all aspects of the study implementation and contributed to the discussion section	developed the study protocol, supervised all aspects of the study implementation and contributed to the discussion section	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Supervision	YES
5090107	27802846	RT	2	performed the laboratory analyses and contributed to the methods section	performed the laboratory analyses and contributed to the methods section	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5090107	27802846	SP	2	completed the data analysis and tables	completed the data analysis and tables	Analyzed the data	Formal analysis	YES
5090107	27802846	SS	2	performed the laboratory analyses and contributed to the methods section	performed the laboratory analyses and contributed to the methods section	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5090107	27802846	ST	2	performed the laboratory analyses and contributed to the methods section	performed the laboratory analyses and contributed to the methods section	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5090107	27802846	TAC	2	developed the data analysis plan and wrote the manuscript	developed the data analysis plan and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6019849	30013770	Ankush Golhar	7	Study design and planning, data acquisition, clinical work, drafted the manuscript. 2	Study design and planning, data acquisition, clinical work, drafted the manuscript. 2	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
6019849	30013770	Naimish Mehta	7	Data acquisition, Clinical work and manuscript revision 6	Data acquisition, Clinical work and manuscript revision 6	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
6019849	30013770	Samiran Nundy	7	Design of work, clinical work and manuscript revision	Design of work, clinical work and manuscript revision	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
6019849	30013770	Shailendra Lalwani	7	Data acquisition, Clinical work and manuscript revision 5	Data acquisition, Clinical work and manuscript revision 5	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
6019849	30013770	Siddharth Mehrotra	7	Data acquisition, clinical work and drafted the manuscript 4	Data acquisition, clinical work and drafted the manuscript 4	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6019849	30013770	Vivek Mangla	7	Study design and planning, clinical work, data acquisition, manuscript revision. 3	Study design and planning, clinical work, data acquisition, manuscript revision. 3	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
4406685	25901960	EL	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406685	25901960	EL	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406685	25901960	EM	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4406685	25901960	EM	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4406685	25901960	EP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4406685	25901960	FB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4406685	25901960	FDI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406685	25901960	FDI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406685	25901960	FDI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406685	25901960	FDI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406685	25901960	GPS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4406685	25901960	IP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406685	25901960	IP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406685	25901960	IP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406685	25901960	IP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406685	25901960	MDB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4406685	25901960	RDL	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4406685	25901960	RDL	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4406685	25901960	RR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406685	25901960	RR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406685	25901960	RR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406685	25901960	SG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406685	25901960	SG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406685	25901960	SG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406685	25901960	SG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406685	25901960	VC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5052249	27709546	GA	2	participated in the data analysis and carefully revised the manuscript	participated in the data analysis and carefully revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5052249	27709546	KIs	2	provided the valuable information about the pet image quality in the j-adni project	provided the valuable information about the pet image quality in the j-adni project	Analyzed the data	Visualization	YES
5052249	27709546	KIt	2	provided the valuable information about the pet image quality in the j-adni project	provided the valuable information about the pet image quality in the j-adni project	Analyzed the data	Visualization	YES
5052249	27709546	PET	2	quality control manager and revised the manuscript critically	quality control manager and revised the manuscript critically	Performed the experiments|Wrote the paper	Project administration|Validation|Writing - Review & Editing	YES
5052249	27709546	TI	2	designed and conducted the j-adni project as the principal investigator	designed and conducted the j-adni project as the principal investigator	Conceived and designed the experiments|Performed the experiments	Conceptualization|Funding acquisition|Investigation|Methodology	YES
5052249	27709546	TN	2	carried out the phantom data acquisition and analysis	carried out the phantom data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5052249	27709546	YI	2	drafted and developed the phantom test criteria and drafted the manuscript	drafted and developed the phantom test criteria and drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5572403	28878790	CC	2	conceived the experiments|conducted the experiments|prepared the data|analyzed the results|prepared the manuscript	conceived the experiments	Conceived and designed the experiments	Conceptualization	YES
5572403	28878790	CC	2	conceived the experiments|conducted the experiments|prepared the data|analyzed the results|prepared the manuscript	conducted the experiments	Performed the experiments	Investigation	YES
5572403	28878790	CC	2	conceived the experiments|conducted the experiments|prepared the data|analyzed the results|prepared the manuscript	prepared the data	-	-	NO
5572403	28878790	CC	2	conceived the experiments|conducted the experiments|prepared the data|analyzed the results|prepared the manuscript	analyzed the results	Analyzed the data	Formal analysis	YES
5572403	28878790	CC	2	conceived the experiments|conducted the experiments|prepared the data|analyzed the results|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5572403	28878790	CJ	2	conducted the experiments|prepared the manuscript	conducted the experiments	Performed the experiments	Investigation	YES
5572403	28878790	CJ	2	conducted the experiments|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5572403	28878790	KO	2	analyzed the results|prepared the manuscript	analyzed the results	Analyzed the data	Formal analysis	YES
5572403	28878790	KO	2	analyzed the results|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5572403	28878790	LL	2	conceived the experiments|conducted the experiments|prepared the data|prepared the manuscript	conceived the experiments	Conceived and designed the experiments	Conceptualization	YES
5572403	28878790	LL	2	conceived the experiments|conducted the experiments|prepared the data|prepared the manuscript	conducted the experiments	Performed the experiments	Investigation	YES
5572403	28878790	LL	2	conceived the experiments|conducted the experiments|prepared the data|prepared the manuscript	prepared the data	-	-	NO
5572403	28878790	LL	2	conceived the experiments|conducted the experiments|prepared the data|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5572403	28878790	MA	2	conceived the experiments|analyzed the results|prepared the manuscript	conceived the experiments	Conceived and designed the experiments	Conceptualization	YES
5572403	28878790	MA	2	conceived the experiments|analyzed the results|prepared the manuscript	analyzed the results	Analyzed the data	Formal analysis	YES
5572403	28878790	MA	2	conceived the experiments|analyzed the results|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5572403	28878790	SU	2	conceived the experiments|conducted the experiments|prepared the manuscript	conceived the experiments	Conceived and designed the experiments	Conceptualization	YES
5572403	28878790	SU	2	conceived the experiments|conducted the experiments|prepared the manuscript	conducted the experiments	Performed the experiments	Investigation	YES
5572403	28878790	SU	2	conceived the experiments|conducted the experiments|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5572403	28878790	VH	2	conducted the experiments|prepared the manuscript	conducted the experiments	Performed the experiments	Investigation	YES
5572403	28878790	VH	2	conducted the experiments|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5572403	28878790	YO	2	conceived the experiments|conducted the experiments|prepared the data|prepared the manuscript	conceived the experiments	Conceived and designed the experiments	Conceptualization	YES
5572403	28878790	YO	2	conceived the experiments|conducted the experiments|prepared the data|prepared the manuscript	conducted the experiments	Performed the experiments	Investigation	YES
5572403	28878790	YO	2	conceived the experiments|conducted the experiments|prepared the data|prepared the manuscript	prepared the data	-	-	NO
5572403	28878790	YO	2	conceived the experiments|conducted the experiments|prepared the data|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
6282921	30524166	A.E.	2	gave substantial contribution to the conception or design of the work in acquisition, analysis, or interpretation of data for the work	gave substantial contribution to the conception or design of the work in acquisition, analysis, or interpretation of data for the work	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
6282921	30524166	Each author	2	participated in article preparing for drafting or revising it critically for important intellectual content, and gave final approval of the version to be published and agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	participated in article preparing for drafting or revising it critically for important intellectual content, and gave final approval of the version to be published and agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6282921	30524166	P.Z.	2	gave substantial contribution to the conception or design of the work in acquisition, analysis, or interpretation of data for the work	gave substantial contribution to the conception or design of the work in acquisition, analysis, or interpretation of data for the work	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
533872	15527499	AEE	2	participated in the design of the study and preparation of biological material	participated in the design of the study and preparation of biological material	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
533872	15527499	AFC	2	participated in rna sample preparation	participated in rna sample preparation	Performed the experiments	Investigation	YES
533872	15527499	AJGS	2	conceived and coordinated the study	conceived and coordinated the study	Conceived and designed the experiments	Conceptualization|Project administration	YES
533872	15527499	DDA	2	participated in all steps of library preparations and analyses	participated in all steps of library preparations and analyses	Analyzed the data	Formal analysis	YES
533872	15527499	DGP	2	performed the bioinformatics analyses	performed the bioinformatics analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
533872	15527499	EDN	2	participated in all steps of library preparations and analyses	participated in all steps of library preparations and analyses	Analyzed the data	Formal analysis	YES
533872	15527499	EME	2	participated in the design of the study, library preparations and conceptual data analysis|conceived and coordinated the study	participated in the design of the study, library preparations and conceptual data analysis	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
533872	15527499	EME	2	participated in the design of the study, library preparations and conceptual data analysis|conceived and coordinated the study	conceived and coordinated the study	Conceived and designed the experiments	Conceptualization|Project administration	YES
533872	15527499	FMFN	2	participated in all steps of library preparations data and analyses	participated in all steps of library preparations data and analyses	Analyzed the data	Formal analysis	YES
533872	15527499	FSE	2	participated in the design of the study, library preparations and conceptual data analysis	participated in the design of the study, library preparations and conceptual data analysis	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
533872	15527499	JFS	2	participated in all steps of library preparations data and analyses|participated in all steps of library preparations and analyses	participated in all steps of library preparations data and analyses	Analyzed the data	Formal analysis	YES
533872	15527499	JFS	2	participated in all steps of library preparations data and analyses|participated in all steps of library preparations and analyses	participated in all steps of library preparations and analyses	Analyzed the data	Formal analysis	YES
533872	15527499	KH	2	participated in the design of the study, library preparations and prepared the manuscript	participated in the design of the study, library preparations and prepared the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
533872	15527499	LFLR	2	participated in rna sample preparation	participated in rna sample preparation	Performed the experiments	Investigation	YES
533872	15527499	MAVC	2	performed the bioinformatics analyses|participated in the design of the study and performed the bioinformatics analyses	performed the bioinformatics analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
533872	15527499	MAVC	2	performed the bioinformatics analyses|participated in the design of the study and performed the bioinformatics analyses	participated in the design of the study and performed the bioinformatics analyses	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
533872	15527499	MAZ	2	conceived and coordinated the study	conceived and coordinated the study	Conceived and designed the experiments	Conceptualization|Project administration	YES
533872	15527499	MCRC	2	sequenced libraries	sequenced libraries	Performed the experiments	Investigation	YES
533872	15527499	MFRS	2	participated in the library preparations and go analysis	participated in the library preparations and go analysis	-	-	NO
533872	15527499	MLPL	2	participated in the design of the study, library preparations and prepared the manuscript|conceived and coordinated the study	participated in the design of the study, library preparations and prepared the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
533872	15527499	MLPL	2	participated in the design of the study, library preparations and prepared the manuscript|conceived and coordinated the study	conceived and coordinated the study	Conceived and designed the experiments	Conceptualization|Project administration	YES
533872	15527499	MMGB	2	participated in the design of the study, library preparations and conceptual data analysis	participated in the design of the study, library preparations and conceptual data analysis	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
533872	15527499	NM	2	participated in the design of the study and preparation of biological material	participated in the design of the study and preparation of biological material	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
533872	15527499	PMVP	2	participated in the library preparations and go analysis	participated in the library preparations and go analysis	-	-	NO
533872	15527499	RGRP	2	participated in the design of the study and preparation of biological material	participated in the design of the study and preparation of biological material	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
533872	15527499	RMM	2	participated in the library preparations and go analysis|participated in all steps of library preparations and analyses	participated in the library preparations and go analysis	-	-	NO
533872	15527499	RMM	2	participated in the library preparations and go analysis|participated in all steps of library preparations and analyses	participated in all steps of library preparations and analyses	Analyzed the data	Formal analysis	YES
533872	15527499	SJS	2	participated in the design of the study and performed the bioinformatics analyses	participated in the design of the study and performed the bioinformatics analyses	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
533872	15527499	VV	2	participated in the design of the study, library preparations and prepared the manuscript|participated in all steps of library preparations and analyses	participated in the design of the study, library preparations and prepared the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
533872	15527499	VV	2	participated in the design of the study, library preparations and prepared the manuscript|participated in all steps of library preparations and analyses	participated in all steps of library preparations and analyses	Analyzed the data	Formal analysis	YES
533872	15527499	WASjr	2	coordinated the design of the study and the bioinformatics analysis|participated in the design of the study and performed the bioinformatics analyses	coordinated the design of the study and the bioinformatics analysis	Conceived and designed the experiments	Formal analysis|Methodology|Project administration	YES
533872	15527499	WASjr	2	coordinated the design of the study and the bioinformatics analysis|participated in the design of the study and performed the bioinformatics analyses	participated in the design of the study and performed the bioinformatics analyses	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
533872	15527499	WKM	2	participated in rna sample preparation	participated in rna sample preparation	Performed the experiments	Investigation	YES
533872	15527499	ZLPS	2	participated in the design of the study, library preparations and conceptual data analysis	participated in the design of the study, library preparations and conceptual data analysis	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
6039880	30002824	AA	7	drafting the manuscript, reviewing and approving the final version	drafting the manuscript, reviewing and approving the final version	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6039880	30002824	BA	7	collecting the data, preparing the manuscript	collecting the data, preparing the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6039880	30002824	IA	7	collecting the data, reviewing the final version	collecting the data, reviewing the final version	Performed the experiments	Investigation	YES
6039880	30002824	SA	7	revising the manuscript, preparing and submitting the manuscript	revising the manuscript, preparing and submitting the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4406686	25901601	AR	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4406686	25901601	DH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406686	25901601	DH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406686	25901601	DH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406686	25901601	DH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406686	25901601	HAK	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406686	25901601	HAK	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406686	25901601	HJS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406686	25901601	JO	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4406686	25901601	MAER	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406686	25901601	MAER	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406686	25901601	MAER	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406686	25901601	MAER	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406686	25901601	SW	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4406686	25901601	WH	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
6340608	30814772	A.A.A.	2	gave substantial contribution to the conception or design of the work and in the acquisition, analysis and interpretation of data for the work	gave substantial contribution to the conception or design of the work and in the acquisition, analysis and interpretation of data for the work	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
6340608	30814772	Each author	2	had role in drafting the work and revising it critically for important intellectual content	had role in drafting the work and revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6340608	30814772	M.A.A.	2	gave substantial contribution to the conception or design of the work and in the acquisition, analysis and interpretation of data for the work	gave substantial contribution to the conception or design of the work and in the acquisition, analysis and interpretation of data for the work	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
6039894	30002822	HN	2	acquired the clinical and pathological data|contributed to editing the manuscript	acquired the clinical and pathological data	Performed the experiments	Investigation	YES
6039894	30002822	HN	2	acquired the clinical and pathological data|contributed to editing the manuscript	contributed to editing the manuscript	Wrote the paper	Writing - Review & Editing	YES
6039894	30002822	KH	2	acquired the clinical and pathological data	acquired the clinical and pathological data	Performed the experiments	Investigation	YES
6039894	30002822	KK	2	acquired the clinical and pathological data	acquired the clinical and pathological data	Performed the experiments	Investigation	YES
6039894	30002822	KM	2	contributed to editing the manuscript	contributed to editing the manuscript	Wrote the paper	Writing - Review & Editing	YES
6039894	30002822	KO	2	acquired the clinical and pathological data	acquired the clinical and pathological data	Performed the experiments	Investigation	YES
6039894	30002822	KS	2	acquired the clinical and pathological data	acquired the clinical and pathological data	Performed the experiments	Investigation	YES
6039894	30002822	MK	2	acquired the clinical and pathological data	acquired the clinical and pathological data	Performed the experiments	Investigation	YES
6039894	30002822	SE	2	acquired the clinical and pathological data	acquired the clinical and pathological data	Performed the experiments	Investigation	YES
6039894	30002822	TN	2	acquired the clinical and pathological data	acquired the clinical and pathological data	Performed the experiments	Investigation	YES
6039894	30002822	TT	2	acquired the clinical and pathological data	acquired the clinical and pathological data	Performed the experiments	Investigation	YES
6039894	30002822	YH	2	wrote the manuscript|acquired the clinical and pathological data	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6039894	30002822	YH	2	wrote the manuscript|acquired the clinical and pathological data	acquired the clinical and pathological data	Performed the experiments	Investigation	YES
5095351	27809960	JW	2	summarized the results of the systematic review	summarized the results of the systematic review	-	-	NO
5095351	27809960	KS	2	summarized the results of the systematic review	summarized the results of the systematic review	-	-	NO
5095351	27809960	NB	2	conducted the literature searches and data extraction|summarized the results of the systematic review	conducted the literature searches and data extraction	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5095351	27809960	NB	2	conducted the literature searches and data extraction|summarized the results of the systematic review	summarized the results of the systematic review	-	-	NO
5572596	28878798	DL	PLoS52	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5572596	28878798	HL	PLoS52	designed the experiments and analyzed the data|wrote the paper	designed the experiments and analyzed the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5572596	28878798	HL	PLoS52	designed the experiments and analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5572596	28878798	QZ	PLoS52	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5572596	28878798	WA	PLoS52	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5572596	28878798	WQ	PLoS52	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5572596	28878798	XL	PLoS52	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5572596	28878798	YY	PLoS52	designed the experiments and analyzed the data|carried out the experiments|wrote the paper	designed the experiments and analyzed the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5572596	28878798	YY	PLoS52	designed the experiments and analyzed the data|carried out the experiments|wrote the paper	carried out the experiments	Performed the experiments	Investigation	YES
5572596	28878798	YY	PLoS52	designed the experiments and analyzed the data|carried out the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
533873	15533247	AH	2	carried out the membrane topology predictions, phylogenetic analysis, domain assignments, rnai studies and analysis of gene expression in the transgenic worm strains	carried out the membrane topology predictions, phylogenetic analysis, domain assignments, rnai studies and analysis of gene expression in the transgenic worm strains	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
533873	15533247	AVG	2	participated in the rnai studies and analysis of gene expression	participated in the rnai studies and analysis of gene expression	Performed the experiments	Investigation	YES
533873	15533247	DB	2	contributed in making the transgenic worm strains	contributed in making the transgenic worm strains	Performed the experiments	Investigation	YES
533873	15533247	ES	2	participated in the membrane topology predictions, phylogenetic analysis and domain assignments	participated in the membrane topology predictions, phylogenetic analysis and domain assignments	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5073088	27766592	BRP	2	assisted prt with the data analysis|performed instrument calibrations, assisted aar with the live phase, developed the listmode sorting scheme for sliding-window sinogram binning, and performed all the image reconstructions	assisted prt with the data analysis	Analyzed the data	Formal analysis	YES
5073088	27766592	BRP	2	assisted prt with the data analysis|performed instrument calibrations, assisted aar with the live phase, developed the listmode sorting scheme for sliding-window sinogram binning, and performed all the image reconstructions	performed instrument calibrations, assisted aar with the live phase, developed the listmode sorting scheme for sliding-window sinogram binning, and performed all the image reconstructions	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
4406687	25902057	AR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406687	25902057	AR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406687	25902057	AR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406687	25902057	AR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406687	25902057	AR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406687	25902057	AW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406687	25902057	AW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406687	25902057	AW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406687	25902057	AW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406687	25902057	AW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406687	25902057	CB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406687	25902057	CB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406687	25902057	CB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406687	25902057	CB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406687	25902057	CB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406687	25902057	KK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406687	25902057	KK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406687	25902057	KK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406687	25902057	KK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406687	25902057	KK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406687	25902057	MF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406687	25902057	MF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406687	25902057	MF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406687	25902057	MF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406687	25902057	MF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406687	25902057	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406687	25902057	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406687	25902057	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406687	25902057	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406687	25902057	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406687	25902057	PS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406687	25902057	PS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406687	25902057	PS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406687	25902057	PS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406687	25902057	PS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406687	25902057	RA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406687	25902057	RA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406687	25902057	RA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406687	25902057	RA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406687	25902057	RA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406687	25902057	SW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406687	25902057	SW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406687	25902057	SW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406687	25902057	SW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406687	25902057	SW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6340609	30814779	Each author	2	gave substantial contribution to the conception or design of the work and in the acquisition, analysis and interpretation of data for the work, had role in drafting the work and revising it critically for important intellectual content|gave final approval of the version to be published and they are agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	gave substantial contribution to the conception or design of the work and in the acquisition, analysis and interpretation of data for the work, had role in drafting the work and revising it critically for important intellectual content	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
6340609	30814779	Each author	2	gave substantial contribution to the conception or design of the work and in the acquisition, analysis and interpretation of data for the work, had role in drafting the work and revising it critically for important intellectual content|gave final approval of the version to be published and they are agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	gave final approval of the version to be published and they are agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	-	-	NO
6039895	30002823	Azam Shoaib	7	Prepared the patient pre-operatively and participated in data collection	Prepared the patient pre-operatively and participated in data collection	Performed the experiments	Investigation	YES
6039895	30002823	Mahmud Aurangzeb	7	Supervised the whole team	Supervised the whole team	-	Supervision	YES
6039895	30002823	Muhammad Muslim	7	Performed the procedure. KaleemUllah: Assisted the consultant in the surgery, participated in data collection	Performed the procedure. KaleemUllah: Assisted the consultant in the surgery, participated in data collection	Performed the experiments	Investigation	YES
6039895	30002823	Nisar Ahmed	7	Data analysis and interpretation	Data analysis and interpretation	Analyzed the data	Formal analysis	YES
6039895	30002823	Zainab Mahsal Khan	7	Study concept and data collection	Study concept and data collection	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
6039895	30002823	ZakaUllah Jan	7	Wrote the paper and assisted the consultant in the procedure	Wrote the paper and assisted the consultant in the procedure	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4508386	26221583	Jana Podzimkova	2	contributed to this review equally	contributed to this review equally	-	-	NO
4508386	26221583	Petr Kuchynka	2	contributed to this review equally	contributed to this review equally	-	-	NO
4406689	25901797	AS	PLoS5	Directly examined asthmatic patients	Directly examined asthmatic patients	Performed the experiments	Investigation	YES
4406689	25901797	GN	PLoS5	Directly examined asthmatic patients	Directly examined asthmatic patients	Performed the experiments	Investigation	YES
4406689	25901797	HC	PLoS5	Directly examined asthmatic patients	Directly examined asthmatic patients	Performed the experiments	Investigation	YES
4406689	25901797	HM	PLoS5	Directly examined asthmatic patients	Directly examined asthmatic patients	Performed the experiments	Investigation	YES
4406689	25901797	HS	PLoS5	Directly examined asthmatic patients	Directly examined asthmatic patients	Performed the experiments	Investigation	YES
4406689	25901797	JH	PLoS5	Directly examined asthmatic patients	Directly examined asthmatic patients	Performed the experiments	Investigation	YES
4406689	25901797	JT	PLoS5	Directly examined asthmatic patients	Directly examined asthmatic patients	Performed the experiments	Investigation	YES
4406689	25901797	MH	PLoS5	Directly examined asthmatic patients	Directly examined asthmatic patients	Performed the experiments	Investigation	YES
4406689	25901797	MI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Directly examined asthmatic patients	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406689	25901797	MI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Directly examined asthmatic patients	Performed the experiments	Performed the experiments	Investigation	YES
4406689	25901797	MI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Directly examined asthmatic patients	Analyzed the data	Analyzed the data	Formal analysis	YES
4406689	25901797	MI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Directly examined asthmatic patients	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406689	25901797	MI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Directly examined asthmatic patients	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406689	25901797	MI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Directly examined asthmatic patients	Directly examined asthmatic patients	Performed the experiments	Investigation	YES
4406689	25901797	NK	PLoS5	Directly examined asthmatic patients	Directly examined asthmatic patients	Performed the experiments	Investigation	YES
4406689	25901797	RK	PLoS5	Directly examined asthmatic patients	Directly examined asthmatic patients	Performed the experiments	Investigation	YES
4406689	25901797	S. Ishii	PLoS5	Directly examined asthmatic patients	Directly examined asthmatic patients	Performed the experiments	Investigation	YES
4406689	25901797	S. Izumi	PLoS5	Directly examined asthmatic patients	Directly examined asthmatic patients	Performed the experiments	Investigation	YES
4406689	25901797	SN	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4406689	25901797	SN	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4406689	25901797	SN	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406689	25901797	SR	PLoS5	Directly examined asthmatic patients	Directly examined asthmatic patients	Performed the experiments	Investigation	YES
4406689	25901797	SW	PLoS5	Directly examined asthmatic patients	Directly examined asthmatic patients	Performed the experiments	Investigation	YES
4406689	25901797	SY	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4406689	25901797	SY	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4406689	25901797	SY	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4508387	26236740	Iman Nabil	2	contributed equally to this work	contributed equally to this work	-	-	NO
4508387	26236740	Noha Attia	2	contributed equally to this work	contributed equally to this work	-	-	NO
4508387	26236740	Radwa A. Mehanna	2	contributed equally to this work	contributed equally to this work	-	-	NO
6340611	30814781	A.C.	2	had role in drafting the work and revising it critically for important intellectual content	had role in drafting the work and revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6340611	30814781	A.T.	2	had role in drafting the work and revising it critically for important intellectual content	had role in drafting the work and revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6340611	30814781	E.B.	2	gave substantial contribution to the conception or design of the work and in the acquisition, analysis and interpretation of data for the work	gave substantial contribution to the conception or design of the work and in the acquisition, analysis and interpretation of data for the work	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
6340611	30814781	E.N.	2	gave substantial contribution to the conception or design of the work and in the acquisition, analysis and interpretation of data for the work	gave substantial contribution to the conception or design of the work and in the acquisition, analysis and interpretation of data for the work	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
6340611	30814781	Each author	2	gave final approval of the version to be published and they are agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	gave final approval of the version to be published and they are agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	-	-	NO
6340611	30814781	M.A.H.	2	had role in drafting the work and revising it critically for important intellectual content	had role in drafting the work and revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6340611	30814781	S.T.	2	had role in drafting the work and revising it critically for important intellectual content	had role in drafting the work and revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6051961	30034801	Anna-Lisa Kutsch	7	data collection and documentation, maintenance of database	data collection and documentation, maintenance of database	Performed the experiments|Contributed reagents/materials/analysis tools	Data curation|Investigation|Software	YES
6051961	30034801	Bettina M. Rau	7	study design, supervision of data collection, analysis of data, writing of manuscript	study design, supervision of data collection, analysis of data, writing of manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Supervision|Writing - Original Draft	YES
6051961	30034801	Christel Weiss	7	statistical analysis, writing of manuscript	statistical analysis, writing of manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6051961	30034801	Ernst Klar	7	writing of manuscript	writing of manuscript	Wrote the paper	Writing - Original Draft	YES
6051961	30034801	Guido Alsfasser	7	analysis of data, supervision of data recruitment, writing of manuscript	analysis of data, supervision of data recruitment, writing of manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Supervision|Writing - Original Draft	YES
6051961	30034801	Johanna Bochow	7	data collection and documentation, maintenance of database	data collection and documentation, maintenance of database	Performed the experiments|Contributed reagents/materials/analysis tools	Data curation|Investigation|Software	YES
6051961	30034801	Malte Weinrich	7	analysis of data, writing of manuscript	analysis of data, writing of manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
533874	15533245	CW	2	performed all the analysis in this paper|contributed to the design, coordination and writing	performed all the analysis in this paper	Performed the experiments	Investigation	YES
533874	15533245	CW	2	performed all the analysis in this paper|contributed to the design, coordination and writing	contributed to the design, coordination and writing	Conceived and designed the experiments|Wrote the paper	Project administration	YES
5572937	28878803	IF	2	analyzed data|wrote the article	analyzed data	Analyzed the data	Formal analysis	YES
5572937	28878803	IF	2	analyzed data|wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
5572937	28878803	MS	2	performed all experiments and data collection	performed all experiments and data collection	Performed the experiments	Investigation	YES
5572937	28878803	PG	2	designed research|analyzed data|wrote the article	designed research	Conceived and designed the experiments	Methodology	YES
5572937	28878803	PG	2	designed research|analyzed data|wrote the article	analyzed data	Analyzed the data	Formal analysis	YES
5572937	28878803	PG	2	designed research|analyzed data|wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
5572937	28878803	RL	2	performed all experiments and data collection	performed all experiments and data collection	Performed the experiments	Investigation	YES
5572937	28878803	TH	2	designed research|performed all experiments and data collection|analyzed data|wrote the article	designed research	Conceived and designed the experiments	Methodology	YES
5572937	28878803	TH	2	designed research|performed all experiments and data collection|analyzed data|wrote the article	performed all experiments and data collection	Performed the experiments	Investigation	YES
5572937	28878803	TH	2	designed research|performed all experiments and data collection|analyzed data|wrote the article	analyzed data	Analyzed the data	Formal analysis	YES
5572937	28878803	TH	2	designed research|performed all experiments and data collection|analyzed data|wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
2186350	17961251	Birthe D. Pedersen	2	were responsible for the entire manuscript	were responsible for the entire manuscript	-	-	NO
2186350	17961251	Mette Ebbesen	2	were responsible for the entire manuscript	were responsible for the entire manuscript	-	-	NO
5103676	27834182	All authors	2	contributed to the design of the work and interpretation of data, contributed to the revisions of the manuscript, gave final approval for publication and agreed to be accountable for the work	contributed to the design of the work and interpretation of data, contributed to the revisions of the manuscript, gave final approval for publication and agreed to be accountable for the work	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
5103676	27834182	CB	2	drafted the manuscript|planned the systematic review	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5103676	27834182	CB	2	drafted the manuscript|planned the systematic review	planned the systematic review	Conceived and designed the experiments	Conceptualization	YES
5103676	27834182	PL	2	drafted the manuscript|planned the systematic review	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5103676	27834182	PL	2	drafted the manuscript|planned the systematic review	planned the systematic review	Conceived and designed the experiments	Conceptualization	YES
5103676	27834182	SDB	2	drafted the manuscript|planned the systematic review	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5103676	27834182	SDB	2	drafted the manuscript|planned the systematic review	planned the systematic review	Conceived and designed the experiments	Conceptualization	YES
5103676	27834182	SWB	2	drafted the manuscript|ran the analyses and created the tables and figures	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5103676	27834182	SWB	2	drafted the manuscript|ran the analyses and created the tables and figures	ran the analyses and created the tables and figures	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
5074934	27770429	AH	2	performed the precursor synthesis and revised the manuscript	performed the precursor synthesis and revised the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5074934	27770429	AS	2	performed the radiochemistry and tracer delivery for human studies	performed the radiochemistry and tracer delivery for human studies	Performed the experiments	Investigation	YES
5074934	27770429	BS	2	designed the trial, performed the experiments, analyzed and revised the data, and wrote and revised the manuscript	designed the trial, performed the experiments, analyzed and revised the data, and wrote and revised the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5074934	27770429	CKD	2	performed the piglet experiments and data acquisition	performed the piglet experiments and data acquisition	Performed the experiments	Investigation	YES
5074934	27770429	JP	2	performed the radiochemistry and tracer delivery for human studies	performed the radiochemistry and tracer delivery for human studies	Performed the experiments	Investigation	YES
5074934	27770429	JS	2	performed the experimental study design and revised the manuscript	performed the experimental study design and revised the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
5074934	27770429	MK	2	performed most of the experiments, analyzed the data, and wrote the manuscript	performed most of the experiments, analyzed the data, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5074934	27770429	MP	2	performed the radiochemistry and tracer delivery for human studies and revised the manuscript	performed the radiochemistry and tracer delivery for human studies and revised the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5074934	27770429	OS	2	is the human study responsible principal investigator and volunteer recruitment for first-in-man study and revised the manuscript	is the human study responsible principal investigator and volunteer recruitment for first-in-man study and revised the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Funding acquisition|Investigation|Writing - Review & Editing	YES
5074934	27770429	PB	2	designed and performed the piglet experiments and wrote and revised the manuscript	designed and performed the piglet experiments and wrote and revised the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5074934	27770429	RS	2	performed the precursor synthesis and revised the manuscript	performed the precursor synthesis and revised the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5074934	27770429	SF	2	performed the radiochemistry and tracer delivery for preclinical experiments	performed the radiochemistry and tracer delivery for preclinical experiments	Performed the experiments	Investigation	YES
5074934	27770429	ST	2	as a study physician took care for the safety of healthy volunteers during recruitment and the actual imaging investigations, performed the tracer application, and revised the manuscript	as a study physician took care for the safety of healthy volunteers during recruitment and the actual imaging investigations, performed the tracer application, and revised the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Investigation|Visualization|Writing - Review & Editing	YES
5074934	27770429	WD-C	2	performed the mice and piglet studies and revised the manuscript	performed the mice and piglet studies and revised the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4406691	25902260	AC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4406691	25902260	AC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406691	25902260	AKS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406691	25902260	AKS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406691	25902260	AKS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406691	25902260	HGK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4406691	25902260	HGK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406691	25902260	RSC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406691	25902260	SMS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4406691	25902260	YFL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406691	25902260	YFL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406691	25902260	YFL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406691	25902260	YL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
6340612	30814770	A.B.	2	had role in drafting the work and revising it critically for important intellectual content	had role in drafting the work and revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6340612	30814770	A.D.N.	2	gave substantial contribution to the conception or design of the work and in the acquisition, analysis and interpretation of data for the work	gave substantial contribution to the conception or design of the work and in the acquisition, analysis and interpretation of data for the work	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
6340612	30814770	A.Dz	2	had role in drafting the work and revising it critically for important intellectual content	had role in drafting the work and revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6340612	30814770	E.B.	2	had role in drafting the work and revising it critically for important intellectual content	had role in drafting the work and revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6340612	30814770	Each author	2	gave final approval of the version to be published and they are agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	gave final approval of the version to be published and they are agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	-	-	NO
6340612	30814770	N.R.	2	gave substantial contribution to the conception or design of the work and in the acquisition, analysis and interpretation of data for the work|had role in drafting the work and revising it critically for important intellectual content	gave substantial contribution to the conception or design of the work and in the acquisition, analysis and interpretation of data for the work	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
6340612	30814770	N.R.	2	gave substantial contribution to the conception or design of the work and in the acquisition, analysis and interpretation of data for the work|had role in drafting the work and revising it critically for important intellectual content	had role in drafting the work and revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
534095	15533246	AJE	2	conceived of the study, and participated in its design and coordination|carried out the gene cloning	conceived of the study, and participated in its design and coordination	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
534095	15533246	AJE	2	conceived of the study, and participated in its design and coordination|carried out the gene cloning	carried out the gene cloning	Performed the experiments	Investigation	YES
534095	15533246	All authors	2	participated in writing the manuscript, read, and approved the final manuscript	participated in writing the manuscript, read, and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
534095	15533246	MAM	2	carried out the gene cloning	carried out the gene cloning	Performed the experiments	Investigation	YES
4927988	27413551	All authors	2	contributed to project design, background research, writing, and editing of the submitted paper	contributed to project design, background research, writing, and editing of the submitted paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft|Writing - Review & Editing	YES
6052194	30034800	Ali Vasefi	7	study design, data collection, data interpretation, writing paper	study design, data collection, data interpretation, writing paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
6052194	30034800	Mahmood Mirzaaghapoor	7	data interpretation, writing paper	data interpretation, writing paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6052194	30034800	Mohammadreza Dehghani	7	study concept, study design, data interpretation, writing paper	study concept, study design, data interpretation, writing paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
5106466	27836020	AO	2	are co-investigators and developed the protocol	are co-investigators and developed the protocol	Conceived and designed the experiments	Methodology	YES
5106466	27836020	All authors	2	participated in discussion of the results and writing of the final paper	participated in discussion of the results and writing of the final paper	Wrote the paper	Writing - Original Draft	YES
5106466	27836020	KCES	2	are co-investigators and developed the protocol|conceived the study and initiated the cohort under the|coordinated the study and trained study workers	are co-investigators and developed the protocol	Conceived and designed the experiments	Methodology	YES
5106466	27836020	KCES	2	are co-investigators and developed the protocol|conceived the study and initiated the cohort under the|coordinated the study and trained study workers	conceived the study and initiated the cohort under the	Conceived and designed the experiments	Conceptualization	YES
5106466	27836020	KCES	2	are co-investigators and developed the protocol|conceived the study and initiated the cohort under the|coordinated the study and trained study workers	coordinated the study and trained study workers	-	Project administration	YES
5106466	27836020	MBvH	2	supervised jc and assisted in conceiving the study and interpreting the data	supervised jc and assisted in conceiving the study and interpreting the data	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Supervision	YES
5106466	27836020	NN	2	supervised the genotypic testing	supervised the genotypic testing	Performed the experiments	Investigation|Supervision	YES
5106466	27836020	PO	2	are co-investigators and developed the protocol|coordinated the study and trained study workers	are co-investigators and developed the protocol	Conceived and designed the experiments	Methodology	YES
5106466	27836020	PO	2	are co-investigators and developed the protocol|coordinated the study and trained study workers	coordinated the study and trained study workers	-	Project administration	YES
5106466	27836020	RB	2	aggregated the data and conducted the analyses of the cohort study	aggregated the data and conducted the analyses of the cohort study	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5106466	27836020	SA	2	coordinated the study and trained study workers	coordinated the study and trained study workers	-	Project administration	YES
5106466	27836020	TA	2	coordinated the study and trained study workers	coordinated the study and trained study workers	-	Project administration	YES
5106466	27836020	TRW	2	are co-investigators and developed the protocol|supervised the conceived the study and initiated the cohort under the|coordinated the study and trained study workers	are co-investigators and developed the protocol	Conceived and designed the experiments	Methodology	YES
5106466	27836020	TRW	2	are co-investigators and developed the protocol|supervised the conceived the study and initiated the cohort under the|coordinated the study and trained study workers	supervised the conceived the study and initiated the cohort under the	Conceived and designed the experiments	Conceptualization|Supervision	YES
5106466	27836020	TRW	2	are co-investigators and developed the protocol|supervised the conceived the study and initiated the cohort under the|coordinated the study and trained study workers	coordinated the study and trained study workers	-	Project administration	YES
5106466	27836020	TSB	2	coordinated the study and trained study workers|aggregated the data and conducted the analyses of the cohort study	coordinated the study and trained study workers	-	Project administration	YES
5106466	27836020	TSB	2	coordinated the study and trained study workers|aggregated the data and conducted the analyses of the cohort study	aggregated the data and conducted the analyses of the cohort study	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5573434	28878791	BB	2	phenotyped the population at both seedling and adult plant stages	phenotyped the population at both seedling and adult plant stages	Performed the experiments	Investigation	YES
5573434	28878791	CL	2	phenotyped the population, did analysis, and wrote the manuscript	phenotyped the population, did analysis, and wrote the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5573434	28878791	DArT	2	ssr markers	ssr markers	-	-	NO
5573434	28878791	JH-E	2	phenotyped the population at both seedling and adult plant stages	phenotyped the population at both seedling and adult plant stages	Performed the experiments	Investigation	YES
5573434	28878791	MR	2	phenotyped the population at both seedling and adult plant stages	phenotyped the population at both seedling and adult plant stages	Performed the experiments	Investigation	YES
5573434	28878791	RS	2	phenotyped the population at both seedling and adult plant stages	phenotyped the population at both seedling and adult plant stages	Performed the experiments	Investigation	YES
5573434	28878791	SH-F	2	phenotyped the population at both seedling and adult plant stages	phenotyped the population at both seedling and adult plant stages	Performed the experiments	Investigation	YES
4406693	25902059	DHK	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406693	25902059	DHL	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406693	25902059	DYC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406693	25902059	DYC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406693	25902059	DYC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406693	25902059	HDJ	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406693	25902059	JHH	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406693	25902059	JKK	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406693	25902059	JYL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406693	25902059	JYL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406693	25902059	JYL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406693	25902059	KSC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406693	25902059	KSC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406693	25902059	KSC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406693	25902059	WSH	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406693	25902059	YDC	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6340613	30814773	all authors	2	were included in all steps of preparation this article	were included in all steps of preparation this article	-	-	NO
534099	15537428	CL	2	performed the rna isolations, chip hybridizations, and data collation	performed the rna isolations, chip hybridizations, and data collation	Performed the experiments	Investigation	YES
534099	15537428	DF	2	participated in data analysis and interpretation	participated in data analysis and interpretation	Analyzed the data	Formal analysis	YES
534099	15537428	DN	2	performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
534099	15537428	DZ	2	performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
534099	15537428	GM	2	conceived and designed the research plan and participated in all aspects of data collection and analysis	conceived and designed the research plan and participated in all aspects of data collection and analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation|Methodology	YES
534099	15537428	HB	2	performed the rna isolations, chip hybridizations, and data collation	performed the rna isolations, chip hybridizations, and data collation	Performed the experiments	Investigation	YES
534099	15537428	JW	2	conceived and designed the research plan and participated in all aspects of data collection and analysis	conceived and designed the research plan and participated in all aspects of data collection and analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation|Methodology	YES
5080272	27783373	KM	2	participated in the design and drafted the manuscript	participated in the design and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
5080272	27783373	KO	2	were responsible for the phantom preparations and helped with the study design	were responsible for the phantom preparations and helped with the study design	Conceived and designed the experiments	Methodology	YES
5080272	27783373	KW	2	assisted with acquisitions, reconstructions, and analysis of data	assisted with acquisitions, reconstructions, and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5080272	27783373	MK	2	drafted the manuscript and revised it critically	drafted the manuscript and revised it critically	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5080272	27783373	NM	2	assisted with acquisitions, reconstructions, and analysis of data	assisted with acquisitions, reconstructions, and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5080272	27783373	TH	2	were responsible for the phantom preparations and helped with the study design	were responsible for the phantom preparations and helped with the study design	Conceived and designed the experiments	Methodology	YES
5080272	27783373	TI	2	assisted with acquisitions, reconstructions, and analysis of data	assisted with acquisitions, reconstructions, and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5080272	27783373	TM	2	was responsible for acquisitions, reconstructions, and data analysis and participated in the study design	was responsible for acquisitions, reconstructions, and data analysis and participated in the study design	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5080272	27783373	TT	2	drafted the manuscript and revised it critically	drafted the manuscript and revised it critically	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5080272	27783373	TU	2	assisted with acquisitions, reconstructions, and analysis of data	assisted with acquisitions, reconstructions, and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5080272	27783373	YM	2	assisted with acquisitions, reconstructions, and analysis of data	assisted with acquisitions, reconstructions, and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6072910	30094024	CN	PLoS52	were involved in study design|wrote up the results and concurrent findings	were involved in study design	Conceived and designed the experiments	Methodology	YES
6072910	30094024	CN	PLoS52	were involved in study design|wrote up the results and concurrent findings	wrote up the results and concurrent findings	Wrote the paper	Writing - Original Draft	YES
6072910	30094024	DP	PLoS52	collected the data	collected the data	Performed the experiments	Investigation	YES
6072910	30094024	LG	PLoS52	were involved in study design|collected the data|analysed the data|wrote up the results and concurrent findings	were involved in study design	Conceived and designed the experiments	Methodology	YES
6072910	30094024	LG	PLoS52	were involved in study design|collected the data|analysed the data|wrote up the results and concurrent findings	collected the data	Performed the experiments	Investigation	YES
6072910	30094024	LG	PLoS52	were involved in study design|collected the data|analysed the data|wrote up the results and concurrent findings	analysed the data	Analyzed the data	Formal analysis	YES
6072910	30094024	LG	PLoS52	were involved in study design|collected the data|analysed the data|wrote up the results and concurrent findings	wrote up the results and concurrent findings	Wrote the paper	Writing - Original Draft	YES
6072910	30094024	RMK	PLoS52	were involved in study design|analysed the data|wrote up the results and concurrent findings	were involved in study design	Conceived and designed the experiments	Methodology	YES
6072910	30094024	RMK	PLoS52	were involved in study design|analysed the data|wrote up the results and concurrent findings	analysed the data	Analyzed the data	Formal analysis	YES
6072910	30094024	RMK	PLoS52	were involved in study design|analysed the data|wrote up the results and concurrent findings	wrote up the results and concurrent findings	Wrote the paper	Writing - Original Draft	YES
6072910	30094024	SK	PLoS52	collected the data	collected the data	Performed the experiments	Investigation	YES
5573446	28878795	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5573446	28878795	GW	2	performed the phylogentic analysis and the rna seq analysis	performed the phylogentic analysis and the rna seq analysis	Performed the experiments	Investigation	YES
5573446	28878795	JG	2	provide help in analysis of qrt pcr and western blot	provide help in analysis of qrt pcr and western blot	Performed the experiments	Investigation	YES
5573446	28878795	JL	2	provide help in analysis of qrt pcr and western blot	provide help in analysis of qrt pcr and western blot	Performed the experiments	Investigation	YES
5573446	28878795	MS	2	provide help in analysis of qrt pcr and western blot	provide help in analysis of qrt pcr and western blot	Performed the experiments	Investigation	YES
5573446	28878795	WJ	2	conceived and designed the experiments, facilitated the project, and assisted in manuscript preparation	conceived and designed the experiments, facilitated the project, and assisted in manuscript preparation	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
5573446	28878795	YL	2	performed the analysis and laboratory assays and wrote the manuscript	performed the analysis and laboratory assays and wrote the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5573446	28878795	ZX	2	performed the phylogentic analysis and the rna seq analysis	performed the phylogentic analysis and the rna seq analysis	Performed the experiments	Investigation	YES
5112354	27852420	CE	2	defined the search terms and performed the initial literature search|reviewed and appraised the titles returned from the search|wrote the manuscript	defined the search terms and performed the initial literature search	Performed the experiments	Formal analysis|Investigation	YES
5112354	27852420	CE	2	defined the search terms and performed the initial literature search|reviewed and appraised the titles returned from the search|wrote the manuscript	reviewed and appraised the titles returned from the search	-	-	NO
5112354	27852420	CE	2	defined the search terms and performed the initial literature search|reviewed and appraised the titles returned from the search|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5112354	27852420	EK	2	reviewed and appraised the titles returned from the search	reviewed and appraised the titles returned from the search	-	-	NO
5112354	27852420	KD	2	commented on the final draft	commented on the final draft	Wrote the paper	Writing - Original Draft	YES
5112354	27852420	MM	2	conceived the project|wrote the manuscript	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5112354	27852420	MM	2	conceived the project|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6340614	30814769	AD	1	Conception and design|Revising it critically for intellectual content	Conception and design	Conceived and designed the experiments	Conceptualization	YES
6340614	30814769	AD	1	Conception and design|Revising it critically for intellectual content	Revising it critically for intellectual content	Wrote the paper	Writing - Review & Editing	YES
6340614	30814769	AG	1	Conception and design|Acquisition, analysis and interpretation of data	Conception and design	Conceived and designed the experiments	Conceptualization	YES
6340614	30814769	AG	1	Conception and design|Acquisition, analysis and interpretation of data	Acquisition, analysis and interpretation of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6340614	30814769	AI	1	Acquisition, analysis and interpretation of data	Acquisition, analysis and interpretation of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6340614	30814769	AR	1	Revising it critically for intellectual content	Revising it critically for intellectual content	Wrote the paper	Writing - Review & Editing	YES
6340614	30814769	FZ	1	Conception and design|Acquisition, analysis and interpretation of data|Revising it critically for intellectual content|Approved final version of the manuscript	Conception and design	Conceived and designed the experiments	Conceptualization	YES
6340614	30814769	FZ	1	Conception and design|Acquisition, analysis and interpretation of data|Revising it critically for intellectual content|Approved final version of the manuscript	Acquisition, analysis and interpretation of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6340614	30814769	FZ	1	Conception and design|Acquisition, analysis and interpretation of data|Revising it critically for intellectual content|Approved final version of the manuscript	Revising it critically for intellectual content	Wrote the paper	Writing - Review & Editing	YES
6340614	30814769	FZ	1	Conception and design|Acquisition, analysis and interpretation of data|Revising it critically for intellectual content|Approved final version of the manuscript	Approved final version of the manuscript	-	-	NO
6340614	30814769	MV	1	Approved final version of the manuscript	Approved final version of the manuscript	-	-	NO
4406696	25902185	CDH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406696	25902185	CDH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406696	25902185	CDH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406696	25902185	CDH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406696	25902185	CDH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406696	25902185	DWP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406696	25902185	DWP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406696	25902185	DWP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406696	25902185	DWP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406696	25902185	DWP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406696	25902185	MJD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406696	25902185	MJD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406696	25902185	MJD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406696	25902185	MJD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406696	25902185	MJD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6340615	30814780	A.C.	2	gave substantial contributions to the conception or design of the work in acquisition, analysis, or interpretation of data for the work	gave substantial contributions to the conception or design of the work in acquisition, analysis, or interpretation of data for the work	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
6340615	30814780	Each author	2	had a part in article preparing for drafting or revising it critically for important intellectual content, and all authors gave final approval of the version to be published and agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	had a part in article preparing for drafting or revising it critically for important intellectual content, and all authors gave final approval of the version to be published and agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6340615	30814780	H.R.	2	gave substantial contributions to the conception or design of the work in acquisition, analysis, or interpretation of data for the work	gave substantial contributions to the conception or design of the work in acquisition, analysis, or interpretation of data for the work	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
5106415	27837548	AB	7	data acquisition, analysis of data, and drafting of manuscript	data acquisition, analysis of data, and drafting of manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5106415	27837548	AM	7	design of the study, data acquisition, analysis and interpretation of data, drafting of manuscript	design of the study, data acquisition, analysis and interpretation of data, drafting of manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5106415	27837548	DA	7	interpretation of data, drafting of manuscript	interpretation of data, drafting of manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5106415	27837548	DB	7	data acquisition, analysis of data, and drafting of manuscript	data acquisition, analysis of data, and drafting of manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5106415	27837548	FBB	7	statistical analysis, analysis of data and critical revision	statistical analysis, analysis of data and critical revision	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5106415	27837548	TB	7	design of the study, data acquisition, analysis and interpretation of data, drafting of manuscript	design of the study, data acquisition, analysis and interpretation of data, drafting of manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5116064	27863535	All	2	working group members reviewed and approved the original manuscript and agreed to be acknowledged, with several working group members providing edits to the paper	working group members reviewed and approved the original manuscript and agreed to be acknowledged, with several working group members providing edits to the paper	Wrote the paper	Writing - Review & Editing	YES
5116064	27863535	DN	2	provided significant edits to the paper	provided significant edits to the paper	Wrote the paper	Writing - Review & Editing	YES
5116064	27863535	RHR	2	provided significant edits to the paper	provided significant edits to the paper	Wrote the paper	Writing - Review & Editing	YES
534115	15504237	AG	2	were responsible for regulatory region analyses and software development	were responsible for regulatory region analyses and software development	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Software	YES
534115	15504237	AGJ	2	were responsible for regulatory region analyses and software development|was responsible for ortholog analysis and novel ortholog assignments|contributed editorial revisions	were responsible for regulatory region analyses and software development	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Software	YES
534115	15504237	AGJ	2	were responsible for regulatory region analyses and software development|was responsible for ortholog analysis and novel ortholog assignments|contributed editorial revisions	was responsible for ortholog analysis and novel ortholog assignments	-	-	NO
534115	15504237	AGJ	2	were responsible for regulatory region analyses and software development|was responsible for ortholog analysis and novel ortholog assignments|contributed editorial revisions	contributed editorial revisions	Wrote the paper	Writing - Review & Editing	YES
534115	15504237	BJA	2	were primarily responsible for the design, coordination and conduct of the study|contributed editorial revisions	were primarily responsible for the design, coordination and conduct of the study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Project administration	YES
534115	15504237	BJA	2	were primarily responsible for the design, coordination and conduct of the study|contributed editorial revisions	contributed editorial revisions	Wrote the paper	Writing - Review & Editing	YES
534115	15504237	CE	2	were responsible for generating, quality assurance, and initial assembly of the gene chip data	were responsible for generating, quality assurance, and initial assembly of the gene chip data	Performed the experiments	Investigation|Validation	YES
534115	15504237	JDK	2	provided purified lymphoid cells, read the manuscript and provided comments and discussion	provided purified lymphoid cells, read the manuscript and provided comments and discussion	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
534115	15504237	JJH	2	were primarily responsible for the design, coordination and conduct of the study|contributed editorial revisions	were primarily responsible for the design, coordination and conduct of the study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Project administration	YES
534115	15504237	JJH	2	were primarily responsible for the design, coordination and conduct of the study|contributed editorial revisions	contributed editorial revisions	Wrote the paper	Writing - Review & Editing	YES
534115	15504237	SK	2	were responsible for generating, quality assurance, and initial assembly of the gene chip data	were responsible for generating, quality assurance, and initial assembly of the gene chip data	Performed the experiments	Investigation|Validation	YES
534115	15504237	SW	2	were responsible for generating, quality assurance, and initial assembly of the gene chip data	were responsible for generating, quality assurance, and initial assembly of the gene chip data	Performed the experiments	Investigation|Validation	YES
4406708	25902142	RB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406708	25902142	RB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406708	25902142	RB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406708	25902142	RB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406708	25902142	SS	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406708	25902142	SS	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406708	25902142	WW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406708	25902142	WW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406708	25902142	WW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406708	25902142	WW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406708	25902142	WW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6083815	30101007	Thomas Husted- Attending	2	physician and editor of final paper	physician and editor of final paper	Wrote the paper	Writing - Review & Editing	YES
6340616	30814774	A.G.	2	conceptualized this study, designed the methodology for data collection, collected and analyzed the data, and wrote the manuscript	conceptualized this study, designed the methodology for data collection, collected and analyzed the data, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
6340616	30814774	E.S.T.	2	extensively supported the development of the study concept, data analysis, and the writing, editing and finalizing of the manuscript	extensively supported the development of the study concept, data analysis, and the writing, editing and finalizing of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
6340616	30814774	F.R.	2	extensively supported the development of the study concept, data analysis, and the writing, editing and finalizing of the manuscript	extensively supported the development of the study concept, data analysis, and the writing, editing and finalizing of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
6340616	30814774	H.P.	2	extensively supported the development of the study concept, data analysis, and the writing, editing and finalizing of the manuscript	extensively supported the development of the study concept, data analysis, and the writing, editing and finalizing of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
6340616	30814774	M.M.I.	2	conceptualized this study, designed the methodology for data collection, collected and analyzed the data, and wrote the manuscript	conceptualized this study, designed the methodology for data collection, collected and analyzed the data, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
6340616	30814774	N.M.	2	assisted in data entry and analysis	assisted in data entry and analysis	Analyzed the data	Data curation|Formal analysis	YES
3664481	23738055	Craig R. Cohen	2	provided overall mentorship on conceptualization, design, and implementation of the study, as well as revising the paper and approving the final draft	provided overall mentorship on conceptualization, design, and implementation of the study, as well as revising the paper and approving the final draft	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
3664481	23738055	Elizabeth A. Bukusi	2	provided overall mentorship on conceptualization, design, and implementation of the study, as well as revising the paper and approving the final draft	provided overall mentorship on conceptualization, design, and implementation of the study, as well as revising the paper and approving the final draft	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
3664481	23738055	Hannah H. Leslie	2	performed the statistical analysis and contributed to drafting of the paper	performed the statistical analysis and contributed to drafting of the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3664481	23738055	Jackson Kioko	2	designed the study instruments, led data collection activities, and substantially contributed to paper development	designed the study instruments, led data collection activities, and substantially contributed to paper development	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3664481	23738055	Jayne Lewis-Kulzer	2	supported study implementation	supported study implementation	Performed the experiments	Investigation	YES
3664481	23738055	Jeremy Penner	2	conceptualized and designed the study, provided mentorship during study conduct, and made substantial contributions to the interpretation of the results and drafting of the paper	conceptualized and designed the study, provided mentorship during study conduct, and made substantial contributions to the interpretation of the results and drafting of the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Supervision|Writing - Original Draft	YES
3664481	23738055	Starley B. Shade	2	provided mentorship for statistical analysis and contributed to paper development	provided mentorship for statistical analysis and contributed to paper development	Analyzed the data	Formal analysis|Supervision	YES
3664481	23738055	Thomas A. Odeny	2	designed and conducted the study, interpreted the data, and drafted the paper	designed and conducted the study, interpreted the data, and drafted the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
3664481	23738055	Walter Adero	2	assisted in the conceptualization, design, and conduct of the study	assisted in the conceptualization, design, and conduct of the study	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
5573539	28878794	all the authors	2	revised and approved the final version to be published, and agreed to be accountable for all aspects of the work in ensuring that any matter regarding the accuracy or integrity of any part of the work are appropriately investigated and resolved	revised and approved the final version to be published, and agreed to be accountable for all aspects of the work in ensuring that any matter regarding the accuracy or integrity of any part of the work are appropriately investigated and resolved	Wrote the paper	Writing - Review & Editing	YES
4406709	25901573	HPQ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406709	25901573	HPQ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406709	25901573	HPQ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406709	25901573	HPQ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406709	25901573	HWG	PLoS5	Revised manuscript	Revised manuscript	Wrote the paper	Writing - Review & Editing	YES
4406709	25901573	XMW	PLoS5	Revised manuscript	Revised manuscript	Wrote the paper	Writing - Review & Editing	YES
4406709	25901573	ZHC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4406709	25901573	ZLZ	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4406709	25901573	ZLZ	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406709	25901573	ZW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406709	25901573	ZW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406709	25901573	ZW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406709	25901573	ZW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5108740	27844449	KI	2	participated in the comprehensive design of the study, evaluated the multiple regression equation, and revised the manuscript	participated in the comprehensive design of the study, evaluated the multiple regression equation, and revised the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
5108740	27844449	KS	2	is the main author|conceived the study, collected the data, and derived the multiple regression equation for estimation of the injected dosage	is the main author	Wrote the paper	Writing - Original Draft	YES
5108740	27844449	KS	2	is the main author|conceived the study, collected the data, and derived the multiple regression equation for estimation of the injected dosage	conceived the study, collected the data, and derived the multiple regression equation for estimation of the injected dosage	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation	YES
5108740	27844449	MH	2	conceived the study, collected the data, and derived the multiple regression equation for estimation of the injected dosage|collected the data and established data collection method	conceived the study, collected the data, and derived the multiple regression equation for estimation of the injected dosage	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation	YES
5108740	27844449	MH	2	conceived the study, collected the data, and derived the multiple regression equation for estimation of the injected dosage|collected the data and established data collection method	collected the data and established data collection method	Performed the experiments	Investigation	YES
5108740	27844449	NT	2	collected the data and established data collection method	collected the data and established data collection method	Performed the experiments	Investigation	YES
5108740	27844449	TI	2	conceived the study, collected the data, and derived the multiple regression equation for estimation of the injected dosage	conceived the study, collected the data, and derived the multiple regression equation for estimation of the injected dosage	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation	YES
5108740	27844449	TM	2	participated in the comprehensive design of the study, evaluated the multiple regression equation, and revised the manuscript	participated in the comprehensive design of the study, evaluated the multiple regression equation, and revised the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
5108740	27844449	TU	2	participated in the comprehensive design of the study, evaluated the multiple regression equation, and revised the manuscript	participated in the comprehensive design of the study, evaluated the multiple regression equation, and revised the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
5108740	27844449	YY	2	collected the data and established data collection method	collected the data and established data collection method	Performed the experiments	Investigation	YES
5120409	27876454	AS	2	are co-principal investigators who assisted with the overall design of the study and offered feedback to the draft manuscript	are co-principal investigators who assisted with the overall design of the study and offered feedback to the draft manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Funding acquisition|Methodology|Writing - Original Draft	YES
5120409	27876454	CB	2	reviewed the manuscript and offered feedback and guidance	reviewed the manuscript and offered feedback and guidance	Wrote the paper	Supervision|Writing - Review & Editing	YES
5120409	27876454	GMHR	2	was the lead writer	was the lead writer	Wrote the paper	-	YES
5120409	27876454	GMS	2	is a co-principal investigator, led all data analysis and co-wrote the methods and results reported here	is a co-principal investigator, led all data analysis and co-wrote the methods and results reported here	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Funding acquisition|Writing - Original Draft	YES
5120409	27876454	KM	2	are co-principal investigators who assisted with the overall design of the study and offered feedback to the draft manuscript	are co-principal investigators who assisted with the overall design of the study and offered feedback to the draft manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Funding acquisition|Methodology|Writing - Original Draft	YES
5120409	27876454	SA	2	are co-principal investigators who assisted with the overall design of the study and offered feedback to the draft manuscript	are co-principal investigators who assisted with the overall design of the study and offered feedback to the draft manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Funding acquisition|Methodology|Writing - Original Draft	YES
5120409	27876454	TDD	2	are co-principal investigators who assisted with the overall design of the study and offered feedback to the draft manuscript	are co-principal investigators who assisted with the overall design of the study and offered feedback to the draft manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Funding acquisition|Methodology|Writing - Original Draft	YES
6340618	30814776	Each author	2	gave substantial contributions to the conception or design of the work in acquisition, analysis, or interpretation of data for the work|had a part in article preparing for drafting or revising it critically for important intellectual content, and each author gave final approval of the version to be published and agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	gave substantial contributions to the conception or design of the work in acquisition, analysis, or interpretation of data for the work	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
6340618	30814776	Each author	2	gave substantial contributions to the conception or design of the work in acquisition, analysis, or interpretation of data for the work|had a part in article preparing for drafting or revising it critically for important intellectual content, and each author gave final approval of the version to be published and agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	had a part in article preparing for drafting or revising it critically for important intellectual content, and each author gave final approval of the version to be published and agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4406710	25901794	AM	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4406710	25901794	AM	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4406710	25901794	AN	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406710	25901794	AN	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406710	25901794	C. Barckhausen	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406710	25901794	C. Barckhausen	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406710	25901794	C. Brendel	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406710	25901794	C. Brendel	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406710	25901794	C. Brendel	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406710	25901794	KS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4406710	25901794	KS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4406710	25901794	MH	PLoS5	Analyzed the data|Discussions|Proofreading	Analyzed the data	Analyzed the data	Formal analysis	YES
4406710	25901794	MH	PLoS5	Analyzed the data|Discussions|Proofreading	Discussions	-	-	NO
4406710	25901794	MH	PLoS5	Analyzed the data|Discussions|Proofreading	Proofreading	-	-	NO
4406710	25901794	MK	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4406710	25901794	MK	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4406710	25901794	MM	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4406710	25901794	PR	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4406710	25901794	PR	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4406710	25901794	ST	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406710	25901794	ST	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406710	25901794	ST	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406710	25901794	TI	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406710	25901794	TS	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2248202	18230171	Brad Olson	2	wrote the first draft	wrote the first draft	Wrote the paper	Writing - Original Draft	YES
2248202	18230171	Martha Davis	2	revised it thoroughly on multiple occasions	revised it thoroughly on multiple occasions	Wrote the paper	Writing - Review & Editing	YES
2248202	18230171	Stephen Soldz	2	revised it thoroughly on multiple occasions	revised it thoroughly on multiple occasions	Wrote the paper	Writing - Review & Editing	YES
5343412	28274201	CB	2	took part in the computational analyses	took part in the computational analyses	Analyzed the data	Formal analysis	YES
5343412	28274201	GRF	2	did most of the tlc analyses	did most of the tlc analyses	Analyzed the data	Formal analysis	YES
5343412	28274201	MBP	2	participated in the computational analyses, data interpretation and contributed to the writing and editing of the paper	participated in the computational analyses, data interpretation and contributed to the writing and editing of the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5343412	28274201	MVB	2	participated in the computational analyses, in dgat3 expression and purification, experimental design, data interpretation and had a major role in manuscript writing and editing	participated in the computational analyses, in dgat3 expression and purification, experimental design, data interpretation and had a major role in manuscript writing and editing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5343412	28274201	NS	2	did most of the tlc analyses	did most of the tlc analyses	Analyzed the data	Formal analysis	YES
5343412	28274201	SEM	2	had a major role in the preparation of anti-dgat3 antisera	had a major role in the preparation of anti-dgat3 antisera	-	-	NO
5343412	28274201	TLC	2	analyses, experimental design, data interpretation and manuscript writing and edition	analyses, experimental design, data interpretation and manuscript writing and edition	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5573714	28883828	MD	2	mainly responsible for providing technical guidance and experimental materials	mainly responsible for providing technical guidance and experimental materials	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources|Supervision	YES
5573714	28883828	MW	2	mainly responsible for providing technical guidance and experimental materials	mainly responsible for providing technical guidance and experimental materials	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources|Supervision	YES
5573714	28883828	MX	2	mainly responsible for the operation of the whole experiment and the writing of the paper	mainly responsible for the operation of the whole experiment and the writing of the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5573714	28883828	QS	2	mainly responsible for providing technical guidance and experimental materials	mainly responsible for providing technical guidance and experimental materials	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources|Supervision	YES
5573714	28883828	SL	2	mainly responsible for assisting the first author in the experiment	mainly responsible for assisting the first author in the experiment	Performed the experiments	Investigation	YES
5573714	28883828	SY	2	mainly responsible for assisting the first author in the experiment	mainly responsible for assisting the first author in the experiment	Performed the experiments	Investigation	YES
5573714	28883828	YL	2	mainly responsible for assisting the first author in the experiment	mainly responsible for assisting the first author in the experiment	Performed the experiments	Investigation	YES
6107901	30167301	A. Husner	2	was the caring otorhinolaryngologist who referred the patient|carried out manuscript editing and reviewing	was the caring otorhinolaryngologist who referred the patient	-	-	NO
6107901	30167301	A. Husner	2	was the caring otorhinolaryngologist who referred the patient|carried out manuscript editing and reviewing	carried out manuscript editing and reviewing	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
6107901	30167301	A. Rabufetti	2	is responsible for concept and definition of intellectual content, documentation and manuscript writing	is responsible for concept and definition of intellectual content, documentation and manuscript writing	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
6107901	30167301	C. Leiggener	2	carried out manuscript editing and reviewing	carried out manuscript editing and reviewing	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
6107901	30167301	M. Augello	2	carried out manuscript editing and reviewing	carried out manuscript editing and reviewing	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5143330	27928774	AMWM	2	provided practical assistance in the development of the phantom and in all experiments	provided practical assistance in the development of the phantom and in all experiments	Performed the experiments	Investigation	YES
5143330	27928774	All authors	2	revised the initial manuscript and approved the final version	revised the initial manuscript and approved the final version	Wrote the paper	Writing - Review & Editing	YES
5143330	27928774	CHS	2	came up with the idea of using a 3d-printed phantom, and advised in the whole project	came up with the idea of using a 3d-printed phantom, and advised in the whole project	Conceived and designed the experiments	Conceptualization	YES
5143330	27928774	EPV	2	supervised the technical and physics parts of the study and the overall writing process	supervised the technical and physics parts of the study and the overall writing process	Wrote the paper	Supervision	YES
5143330	27928774	GJL	2	provided essential assistance in the phantom design and constructed the phantom	provided essential assistance in the phantom design and constructed the phantom	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5143330	27928774	HK	2	provided essential assistance in the phantom design and constructed the phantom	provided essential assistance in the phantom design and constructed the phantom	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5143330	27928774	LHCP	2	performed experiment 2 and analysed these data	performed experiment 2 and analysed these data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5143330	27928774	LND	2	performed experiment 1, analysed these data and the whole set of data, wrote parts of the manuscript and made the figures	performed experiment 1, analysed these data and the whole set of data, wrote parts of the manuscript and made the figures	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Visualization|Writing - Original Draft	YES
5143330	27928774	MG	2	supervised the project being part of a larger beta image project and secured the clinical relevance of this phantom study	supervised the project being part of a larger beta image project and secured the clinical relevance of this phantom study	Analyzed the data	Supervision|Visualization	YES
5143330	27928774	MK	2	designed the phantom and provided technical writing assistance	designed the phantom and provided technical writing assistance	Conceived and designed the experiments|Wrote the paper	-	YES
5143330	27928774	WW	2	participated in the phantom development, the design, the coordination and overall analysis of the experiments and drafted the manuscript	participated in the phantom development, the design, the coordination and overall analysis of the experiments and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Project administration|Writing - Original Draft	YES
4406711	25901352	DSL	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406711	25901352	DSL	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406711	25901352	JHJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406711	25901352	JHJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406711	25901352	JHJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406711	25901352	JHJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406711	25901352	WK	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406711	25901352	WK	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406711	25901352	WK	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406711	25901352	WK	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5124108	27887669	AJR	PLoS52	conceptualized and designed the study|analyzed the data|wrote the paper|reviewed and edited the manuscript	conceptualized and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5124108	27887669	AJR	PLoS52	conceptualized and designed the study|analyzed the data|wrote the paper|reviewed and edited the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5124108	27887669	AJR	PLoS52	conceptualized and designed the study|analyzed the data|wrote the paper|reviewed and edited the manuscript	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5124108	27887669	AJR	PLoS52	conceptualized and designed the study|analyzed the data|wrote the paper|reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5124108	27887669	AMH	PLoS52	conceptualized and designed the study|analyzed the data|reviewed and edited the manuscript	conceptualized and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5124108	27887669	AMH	PLoS52	conceptualized and designed the study|analyzed the data|reviewed and edited the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5124108	27887669	AMH	PLoS52	conceptualized and designed the study|analyzed the data|reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5124108	27887669	EAB	PLoS52	conceptualized and designed the study|reviewed and edited the manuscript	conceptualized and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5124108	27887669	EAB	PLoS52	conceptualized and designed the study|reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5124108	27887669	EW	PLoS52	acquired the data|analyzed the data|reviewed and edited the manuscript	acquired the data	Performed the experiments	Investigation	YES
5124108	27887669	EW	PLoS52	acquired the data|analyzed the data|reviewed and edited the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5124108	27887669	EW	PLoS52	acquired the data|analyzed the data|reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5124108	27887669	JMT	PLoS52	conceptualized and designed the study|wrote the paper|reviewed and edited the manuscript	conceptualized and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5124108	27887669	JMT	PLoS52	conceptualized and designed the study|wrote the paper|reviewed and edited the manuscript	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5124108	27887669	JMT	PLoS52	conceptualized and designed the study|wrote the paper|reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5124108	27887669	LA	PLoS52	acquired the data|analyzed the data|reviewed and edited the manuscript	acquired the data	Performed the experiments	Investigation	YES
5124108	27887669	LA	PLoS52	acquired the data|analyzed the data|reviewed and edited the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5124108	27887669	LA	PLoS52	acquired the data|analyzed the data|reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5124108	27887669	LAD	PLoS52	conceptualized and designed the study|wrote the paper|reviewed and edited the manuscript	conceptualized and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5124108	27887669	LAD	PLoS52	conceptualized and designed the study|wrote the paper|reviewed and edited the manuscript	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5124108	27887669	LAD	PLoS52	conceptualized and designed the study|wrote the paper|reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5124108	27887669	PLM	PLoS52	acquired the data|analyzed the data|reviewed and edited the manuscript	acquired the data	Performed the experiments	Investigation	YES
5124108	27887669	PLM	PLoS52	acquired the data|analyzed the data|reviewed and edited the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5124108	27887669	PLM	PLoS52	acquired the data|analyzed the data|reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5124108	27887669	ZK	PLoS52	conceptualized and designed the study|reviewed and edited the manuscript	conceptualized and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5124108	27887669	ZK	PLoS52	conceptualized and designed the study|reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
6340619	30814768	The author	2	was included in all phases of preparation this article and gave final approval of the version to be published and agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	was included in all phases of preparation this article and gave final approval of the version to be published and agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	-	-	NO
5345146	28283023	All authors	2	made substantial contributions to conception and design, or acquisition of data, or analysis and interpretation of data, and all were involved in critical revision of the manuscript and gave approval for publication	made substantial contributions to conception and design, or acquisition of data, or analysis and interpretation of data, and all were involved in critical revision of the manuscript and gave approval for publication	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Resources|Writing - Review & Editing	YES
5573715	28883827	CH	2	designed the study and helped to write the manuscript	designed the study and helped to write the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5573715	28883827	FM	2	designed and performed the field experiments	designed and performed the field experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5573715	28883827	HW	2	carried out the experiments, analyzed the data, and wrote the manuscript	carried out the experiments, analyzed the data, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5573715	28883827	KL	2	carried out the experiments, analyzed the data, and wrote the manuscript	carried out the experiments, analyzed the data, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5573715	28883827	QW	2	designed and performed the field experiments	designed and performed the field experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5573715	28883827	XH	2	assisted in data collection and analysis	assisted in data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5573715	28883827	YW	2	assisted in data collection and analysis	assisted in data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5573715	28883827	ZL	2	designed the study and helped to write the manuscript	designed the study and helped to write the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4406712	25902141	JW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Created the stimuli|Supervised the project	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406712	25902141	JW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Created the stimuli|Supervised the project	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406712	25902141	JW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Created the stimuli|Supervised the project	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406712	25902141	JW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Created the stimuli|Supervised the project	Created the stimuli	-	-	NO
4406712	25902141	JW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Created the stimuli|Supervised the project	Supervised the project	-	Supervision	YES
4406712	25902141	TB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406712	25902141	TB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406712	25902141	TB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406712	25902141	VP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406712	25902141	VP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406712	25902141	VP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406712	25902141	VP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6108073	30167300	AJ	2	saw the patient|reviewed manuscript	saw the patient	-	-	NO
6108073	30167300	AJ	2	saw the patient|reviewed manuscript	reviewed manuscript	Wrote the paper	Writing - Review & Editing	YES
6108073	30167300	BA	2	reviewed manuscript	reviewed manuscript	Wrote the paper	Writing - Review & Editing	YES
6108073	30167300	MD	2	gathered the patients data and wrote the manuscript|reviewed manuscript	gathered the patients data and wrote the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6108073	30167300	MD	2	gathered the patients data and wrote the manuscript|reviewed manuscript	reviewed manuscript	Wrote the paper	Writing - Review & Editing	YES
6108073	30167300	NO	2	gathered the patients data and wrote the manuscript|saw the patient|reviewed manuscript	gathered the patients data and wrote the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6108073	30167300	NO	2	gathered the patients data and wrote the manuscript|saw the patient|reviewed manuscript	saw the patient	-	-	NO
6108073	30167300	NO	2	gathered the patients data and wrote the manuscript|saw the patient|reviewed manuscript	reviewed manuscript	Wrote the paper	Writing - Review & Editing	YES
5153396	27957730	AW	2	conceived of the concept and design and participated in the critical revision of the manuscript	conceived of the concept and design and participated in the critical revision of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5153396	27957730	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5153396	27957730	CZ	2	conceived of the concept and design and participated in the critical revision of the manuscript|drafted the manuscript and carried out the data analysis and interpretation	conceived of the concept and design and participated in the critical revision of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5153396	27957730	CZ	2	conceived of the concept and design and participated in the critical revision of the manuscript|drafted the manuscript and carried out the data analysis and interpretation	drafted the manuscript and carried out the data analysis and interpretation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5153396	27957730	EV	2	conceived of the concept and design and participated in the critical revision of the manuscript|drafted the manuscript and carried out the data analysis and interpretation	conceived of the concept and design and participated in the critical revision of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5153396	27957730	EV	2	conceived of the concept and design and participated in the critical revision of the manuscript|drafted the manuscript and carried out the data analysis and interpretation	drafted the manuscript and carried out the data analysis and interpretation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5153396	27957730	FM	2	conceived of the concept and design and participated in the critical revision of the manuscript	conceived of the concept and design and participated in the critical revision of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5153396	27957730	PL	2	conceived of the concept and design and participated in the critical revision of the manuscript|approved the final content	conceived of the concept and design and participated in the critical revision of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5153396	27957730	PL	2	conceived of the concept and design and participated in the critical revision of the manuscript|approved the final content	approved the final content	-	-	NO
5153396	27957730	RB	2	conceived of the concept and design and participated in the critical revision of the manuscript|contributed to and reviewed data analysis|approved the final content	conceived of the concept and design and participated in the critical revision of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5153396	27957730	RB	2	conceived of the concept and design and participated in the critical revision of the manuscript|contributed to and reviewed data analysis|approved the final content	contributed to and reviewed data analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5153396	27957730	RB	2	conceived of the concept and design and participated in the critical revision of the manuscript|contributed to and reviewed data analysis|approved the final content	approved the final content	-	-	NO
5153396	27957730	RW	2	conceived of the concept and design and participated in the critical revision of the manuscript	conceived of the concept and design and participated in the critical revision of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5153396	27957730	WV	2	conceived of the concept and design and participated in the critical revision of the manuscript	conceived of the concept and design and participated in the critical revision of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
6340620	30814771	E.K.H.	2	gave substantial contribution to the conception or design of the work and in the acquisition, analysis and interpretation of data for the work	gave substantial contribution to the conception or design of the work and in the acquisition, analysis and interpretation of data for the work	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
6340620	30814771	Each author	2	had role in drafting the work and revising it critically for important intellectual content	had role in drafting the work and revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6340620	30814771	N.O.K.	2	gave substantial contribution to the conception or design of the work and in the acquisition, analysis and interpretation of data for the work	gave substantial contribution to the conception or design of the work and in the acquisition, analysis and interpretation of data for the work	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
5573723	28883826	AE	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5573723	28883826	CL	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5573723	28883826	GB	PLoS52	conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5573723	28883826	HB	PLoS52	designed the experiments|performed the experiments|wrote the paper	designed the experiments	Conceived and designed the experiments	Methodology	YES
5573723	28883826	HB	PLoS52	designed the experiments|performed the experiments|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5573723	28883826	HB	PLoS52	designed the experiments|performed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5573723	28883826	MaM	PLoS52	conceived the study|designed the experiments|wrote the paper	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5573723	28883826	MaM	PLoS52	conceived the study|designed the experiments|wrote the paper	designed the experiments	Conceived and designed the experiments	Methodology	YES
5573723	28883826	MaM	PLoS52	conceived the study|designed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5573723	28883826	NH	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5573723	28883826	ZA	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
2265736	18269763	The authors	2	contributed equally to the writing of the manuscript	contributed equally to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5134746	27914185	All authors	2	contributed extensively to the work presented in this paper	contributed extensively to the work presented in this paper	-	-	NO
5134746	27914185	EJM	2	conceived the study|created the literature search strategy, built the data extraction file and supervised the project|drafted the manuscript, and all the other authors helped revise the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5134746	27914185	EJM	2	conceived the study|created the literature search strategy, built the data extraction file and supervised the project|drafted the manuscript, and all the other authors helped revise the manuscript	created the literature search strategy, built the data extraction file and supervised the project	Analyzed the data	Data curation|Formal analysis|Supervision	YES
5134746	27914185	EJM	2	conceived the study|created the literature search strategy, built the data extraction file and supervised the project|drafted the manuscript, and all the other authors helped revise the manuscript	drafted the manuscript, and all the other authors helped revise the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5134746	27914185	JBN	2	provided technical support and conceptual advice	provided technical support and conceptual advice	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5134746	27914185	JF	2	provided technical support and conceptual advice	provided technical support and conceptual advice	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5134746	27914185	JJHP	2	drafted the manuscript, and all the other authors helped revise the manuscript	drafted the manuscript, and all the other authors helped revise the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5134746	27914185	KC	2	performed the statistical analyses, and all authors interpreted the data	performed the statistical analyses, and all authors interpreted the data	Analyzed the data	Formal analysis	YES
5134746	27914185	KT	2	performed the statistical analyses, and all authors interpreted the data	performed the statistical analyses, and all authors interpreted the data	Analyzed the data	Formal analysis	YES
5134746	27914185	NF	2	conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5134746	27914185	SK	2	conceived the study|created the literature search strategy, built the data extraction file and supervised the project|performed the statistical analyses, and all authors interpreted the data	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5134746	27914185	SK	2	conceived the study|created the literature search strategy, built the data extraction file and supervised the project|performed the statistical analyses, and all authors interpreted the data	created the literature search strategy, built the data extraction file and supervised the project	Analyzed the data	Data curation|Formal analysis|Supervision	YES
5134746	27914185	SK	2	conceived the study|created the literature search strategy, built the data extraction file and supervised the project|performed the statistical analyses, and all authors interpreted the data	performed the statistical analyses, and all authors interpreted the data	Analyzed the data	Formal analysis	YES
5346207	28284188	DB	PLoS52	contributed reagents/materials/analysis tools|critically revised the manuscript	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5346207	28284188	DB	PLoS52	contributed reagents/materials/analysis tools|critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5346207	28284188	EV	PLoS52	performed the experiments|analyzed the data|critically revised the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5346207	28284188	EV	PLoS52	performed the experiments|analyzed the data|critically revised the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5346207	28284188	EV	PLoS52	performed the experiments|analyzed the data|critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5346207	28284188	GP	PLoS52	performed the experiments|critically revised the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5346207	28284188	GP	PLoS52	performed the experiments|critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5346207	28284188	IV	PLoS52	conceived and designed the experiments|analyzed the data|contributed reagents/materials/analysis tools|wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5346207	28284188	IV	PLoS52	conceived and designed the experiments|analyzed the data|contributed reagents/materials/analysis tools|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5346207	28284188	IV	PLoS52	conceived and designed the experiments|analyzed the data|contributed reagents/materials/analysis tools|wrote the manuscript	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5346207	28284188	IV	PLoS52	conceived and designed the experiments|analyzed the data|contributed reagents/materials/analysis tools|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5346207	28284188	JG	PLoS52	performed the experiments|analyzed the data|contributed reagents/materials/analysis tools	performed the experiments	Performed the experiments	Investigation	YES
5346207	28284188	JG	PLoS52	performed the experiments|analyzed the data|contributed reagents/materials/analysis tools	analyzed the data	Analyzed the data	Formal analysis	YES
5346207	28284188	JG	PLoS52	performed the experiments|analyzed the data|contributed reagents/materials/analysis tools	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5346207	28284188	JJ	PLoS52	performed the experiments|analyzed the data|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5346207	28284188	JJ	PLoS52	performed the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5346207	28284188	JJ	PLoS52	performed the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5346207	28284188	JS	PLoS52	conceived and designed the experiments|analyzed the data|contributed reagents/materials/analysis tools|critically revised the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5346207	28284188	JS	PLoS52	conceived and designed the experiments|analyzed the data|contributed reagents/materials/analysis tools|critically revised the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5346207	28284188	JS	PLoS52	conceived and designed the experiments|analyzed the data|contributed reagents/materials/analysis tools|critically revised the manuscript	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5346207	28284188	JS	PLoS52	conceived and designed the experiments|analyzed the data|contributed reagents/materials/analysis tools|critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5346207	28284188	LD	PLoS52	performed the experiments|analyzed the data|critically revised the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5346207	28284188	LD	PLoS52	performed the experiments|analyzed the data|critically revised the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5346207	28284188	LD	PLoS52	performed the experiments|analyzed the data|critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5346207	28284188	LG	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5346207	28284188	LR	PLoS52	performed the experiments|contributed reagents/materials/analysis tools	performed the experiments	Performed the experiments	Investigation	YES
5346207	28284188	LR	PLoS52	performed the experiments|contributed reagents/materials/analysis tools	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5346207	28284188	MT	PLoS52	contributed reagents/materials/analysis tools|critically revised the manuscript	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5346207	28284188	MT	PLoS52	contributed reagents/materials/analysis tools|critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5346207	28284188	MTD	PLoS52	analyzed the data|critically revised the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5346207	28284188	MTD	PLoS52	analyzed the data|critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5346207	28284188	RP	PLoS52	performed the experiments|critically revised the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5346207	28284188	RP	PLoS52	performed the experiments|critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5346207	28284188	SM	PLoS52	performed the experiments|analyzed the data|critically revised the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5346207	28284188	SM	PLoS52	performed the experiments|analyzed the data|critically revised the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5346207	28284188	SM	PLoS52	performed the experiments|analyzed the data|critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5346207	28284188	SS	PLoS52	performed the experiments|analyzed the data|contributed reagents/materials/analysis tools	performed the experiments	Performed the experiments	Investigation	YES
5346207	28284188	SS	PLoS52	performed the experiments|analyzed the data|contributed reagents/materials/analysis tools	analyzed the data	Analyzed the data	Formal analysis	YES
5346207	28284188	SS	PLoS52	performed the experiments|analyzed the data|contributed reagents/materials/analysis tools	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5346207	28284188	ST	PLoS52	conceived and designed the experiments|analyzed the data|contributed reagents/materials/analysis tools|wrote the manuscript|critically revised the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5346207	28284188	ST	PLoS52	conceived and designed the experiments|analyzed the data|contributed reagents/materials/analysis tools|wrote the manuscript|critically revised the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5346207	28284188	ST	PLoS52	conceived and designed the experiments|analyzed the data|contributed reagents/materials/analysis tools|wrote the manuscript|critically revised the manuscript	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5346207	28284188	ST	PLoS52	conceived and designed the experiments|analyzed the data|contributed reagents/materials/analysis tools|wrote the manuscript|critically revised the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5346207	28284188	ST	PLoS52	conceived and designed the experiments|analyzed the data|contributed reagents/materials/analysis tools|wrote the manuscript|critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5346207	28284188	VA	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
4406713	25901740	GJJ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4406713	25901740	IN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406713	25901740	IN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406713	25901740	IN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406713	25901740	IN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406713	25901740	KK	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4406713	25901740	KK	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4406713	25901740	MM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406713	25901740	MM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406713	25901740	MM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406713	25901740	MM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406713	25901740	RR	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406713	25901740	RSK	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4406713	25901740	RSK	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4406713	25901740	TI	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406713	25901740	TI	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406713	25901740	VON	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406713	25901740	VON	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406713	25901740	VON	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406713	25901740	VON	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406713	25901740	VON	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6340622	30814778	LG	2	gave substantial contributions to design, acquisition of data, interpretation of data, drafting the article, revising, final approval of the version	gave substantial contributions to design, acquisition of data, interpretation of data, drafting the article, revising, final approval of the version	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
6340622	30814778	TV	2	gave substantial contributions to the conception, design, acquisition of data, revising, final approval of the version	gave substantial contributions to the conception, design, acquisition of data, revising, final approval of the version	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceptualization|Investigation|Resources	YES
5573811	28883829	AR	2	performed voc analyses	performed voc analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5573811	28883829	BA	2	performed genome analysis, sesquiterpene synthase isolation, expression analysis and functional characterization and drafted the manuscript	performed genome analysis, sesquiterpene synthase isolation, expression analysis and functional characterization and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5573811	28883829	LP	2	conceived, designed, and supervised the study	conceived, designed, and supervised the study	Conceived and designed the experiments	Conceptualization|Methodology|Supervision	YES
5573811	28883829	MP	2	performed protein molecular modeling and interpreted the results	performed protein molecular modeling and interpreted the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5161052	27987183	BE	2	designed the study, obtained ethics approval, collected and provided patient data, and wrote the patient information section	designed the study, obtained ethics approval, collected and provided patient data, and wrote the patient information section	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Methodology|Project administration|Resources|Writing - Original Draft	YES
5161052	27987183	CW	2	provided the theory, processed and analysed data, and wrote the first draft of the manuscript	provided the theory, processed and analysed data, and wrote the first draft of the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Data curation|Formal analysis|Resources|Writing - Original Draft	YES
5161052	27987183	MW	2	have participated in computer programming, organizing and interpretation of data, and drafting and editing the manuscript	have participated in computer programming, organizing and interpretation of data, and drafting and editing the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Software|Writing - Original Draft|Writing - Review & Editing	YES
5161052	27987183	PB	2	have participated in computer programming, organizing and interpretation of data, and drafting and editing the manuscript	have participated in computer programming, organizing and interpretation of data, and drafting and editing the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Software|Writing - Original Draft|Writing - Review & Editing	YES
5161052	27987183	SW	2	have participated in computer programming, organizing and interpretation of data, and drafting and editing the manuscript	have participated in computer programming, organizing and interpretation of data, and drafting and editing the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Software|Writing - Original Draft|Writing - Review & Editing	YES
6111052	30167304	Daniela Codrich	2	contributed to data collection	contributed to data collection	Performed the experiments	Investigation	YES
6111052	30167304	Edoardo Guida	2	wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
6111052	30167304	Enrica Verzotti	2	wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
6111052	30167304	Federica Pederiva	2	contributed to data collection	contributed to data collection	Performed the experiments	Investigation	YES
6111052	30167304	Jurgen Schleef	2	supervised this study	supervised this study	-	Supervision	YES
6111052	30167304	Massimo Di Grazia	2	contributed to the psychological part of the manuscript	contributed to the psychological part of the manuscript	-	-	NO
5136137	27914186	AG	2	wrote the first draft	wrote the first draft	Wrote the paper	Writing - Original Draft	YES
5136137	27914186	All authors	2	contributed and approved the final version	contributed and approved the final version	-	-	NO
5136137	27914186	HB	2	wrote the first draft	wrote the first draft	Wrote the paper	Writing - Original Draft	YES
4510121	26236721	Afrin Sultana Chowdhury	2	carried out the molecular genetic studies, participated in the sequence alignment, and drafted the paper	carried out the molecular genetic studies, participated in the sequence alignment, and drafted the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4510121	26236721	Amit Datta	2	has made substantial contributions to conception and design, acquisition of data, and analysis and interpretation of data	has made substantial contributions to conception and design, acquisition of data, and analysis and interpretation of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
4510121	26236721	Anayet Hasan	2	worked for computational analysis, conceived of the study, and participated in its design and coordination and helped to draft the paper	worked for computational analysis, conceived of the study, and participated in its design and coordination and helped to draft the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Project administration|Writing - Original Draft	YES
4510121	26236721	Habibul Hasan Mazumder	2	carried out the molecular genetic studies, participated in the sequence alignment, and drafted the paper	carried out the molecular genetic studies, participated in the sequence alignment, and drafted the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6340623	30814777	A.T.T.	2	had role in drafting the work and revising it critically for important intellectual content	had role in drafting the work and revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6340623	30814777	Dj.O.	2	gave substantial contribution to the conception or design of the work and in the acquisition, analysis and interpretation of data for the work|had role in drafting the work and revising it critically for important intellectual content	gave substantial contribution to the conception or design of the work and in the acquisition, analysis and interpretation of data for the work	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
6340623	30814777	Dj.O.	2	gave substantial contribution to the conception or design of the work and in the acquisition, analysis and interpretation of data for the work|had role in drafting the work and revising it critically for important intellectual content	had role in drafting the work and revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6340623	30814777	Dz.J.	2	gave substantial contribution to the conception or design of the work and in the acquisition, analysis and interpretation of data for the work|had role in drafting the work and revising it critically for important intellectual content	gave substantial contribution to the conception or design of the work and in the acquisition, analysis and interpretation of data for the work	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
6340623	30814777	Dz.J.	2	gave substantial contribution to the conception or design of the work and in the acquisition, analysis and interpretation of data for the work|had role in drafting the work and revising it critically for important intellectual content	had role in drafting the work and revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6340623	30814777	Each author	2	gave final approval of the version to be published and they agreed to be accountable for all aspects of the work in ensuring the questions related to the accuracy or integrity of any part of the work	gave final approval of the version to be published and they agreed to be accountable for all aspects of the work in ensuring the questions related to the accuracy or integrity of any part of the work	-	-	NO
6340623	30814777	F.Dz	2	had role in drafting the work and revising it critically for important intellectual content	had role in drafting the work and revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
2276227	18248665	TSH	2	wrote the first draft	wrote the first draft	Wrote the paper	Writing - Original Draft	YES
6111054	30167303	Al-Aqilah Jamaluddin	2	participated in the writing of this paper	participated in the writing of this paper	Wrote the paper	Writing - Original Draft	YES
6111054	30167303	Durkahshinii Gunasaker	2	participated in the writing of this paper	participated in the writing of this paper	Wrote the paper	Writing - Original Draft	YES
6111054	30167303	Ken Leong Tay	2	were involved in the surgery	were involved in the surgery	Performed the experiments	Investigation	YES
6111054	30167303	Phong Jhiew Khoo	2	is the main/first author and corresponding author of this paper|were involved in the surgery	is the main/first author and corresponding author of this paper	-	-	NO
6111054	30167303	Phong Jhiew Khoo	2	is the main/first author and corresponding author of this paper|were involved in the surgery	were involved in the surgery	Performed the experiments	Investigation	YES
4406715	25901993	AKCB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406715	25901993	AKCB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406715	25901993	CS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4406715	25901993	MB	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406715	25901993	MFB	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406715	25901993	MN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406715	25901993	MN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406715	25901993	MN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406715	25901993	MN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406715	25901993	PCL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406715	25901993	PCL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406715	25901993	TdK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406715	25901993	TdK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406715	25901993	TdK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406715	25901993	TdK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406715	25901993	WGDF	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5573840	28883825	AA	2	prepared the seed material|compiled information about ecology and phylogeny of the species	prepared the seed material	Performed the experiments	Investigation	YES
5573840	28883825	AA	2	prepared the seed material|compiled information about ecology and phylogeny of the species	compiled information about ecology and phylogeny of the species	-	-	NO
5573840	28883825	All authors	2	contributed to the discussion of the results and the writing of the work and approved the final version of the manuscript	contributed to the discussion of the results and the writing of the work and approved the final version of the manuscript	Wrote the paper	Writing - Original Draft	YES
5573840	28883825	BF-M	2	designed the study|carried out the germination experiment and the hplc analyses|drafted the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5573840	28883825	BF-M	2	designed the study|carried out the germination experiment and the hplc analyses|drafted the manuscript	carried out the germination experiment and the hplc analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5573840	28883825	BF-M	2	designed the study|carried out the germination experiment and the hplc analyses|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5573840	28883825	FM	2	carried out the germination experiment and the hplc analyses|compiled information about ecology and phylogeny of the species	carried out the germination experiment and the hplc analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5573840	28883825	FM	2	carried out the germination experiment and the hplc analyses|compiled information about ecology and phylogeny of the species	compiled information about ecology and phylogeny of the species	-	-	NO
5573840	28883825	IK	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5573840	28883825	JB	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5573840	28883825	JG-P	2	designed the study|drafted the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5573840	28883825	JG-P	2	designed the study|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5573840	28883825	LC	2	prepared the seed material|drafted the manuscript|compiled information about ecology and phylogeny of the species	prepared the seed material	Performed the experiments	Investigation	YES
5573840	28883825	LC	2	prepared the seed material|drafted the manuscript|compiled information about ecology and phylogeny of the species	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5573840	28883825	LC	2	prepared the seed material|drafted the manuscript|compiled information about ecology and phylogeny of the species	compiled information about ecology and phylogeny of the species	-	-	NO
5573840	28883825	LM-F	2	compiled information about ecology and phylogeny of the species|did the statistical analyses	compiled information about ecology and phylogeny of the species	-	-	NO
5573840	28883825	LM-F	2	compiled information about ecology and phylogeny of the species|did the statistical analyses	did the statistical analyses	Analyzed the data	Formal analysis	YES
5216001	28058674	HJH	2	provided technical support for the data analysis	provided technical support for the data analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5216001	28058674	JN	2	evaluated the data	evaluated the data	-	-	NO
5216001	28058674	ML	2	initiated and designed the study|evaluated the data|performed the statistical analysis and drafted the manuscript	initiated and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5216001	28058674	ML	2	initiated and designed the study|evaluated the data|performed the statistical analysis and drafted the manuscript	evaluated the data	-	-	NO
5216001	28058674	ML	2	initiated and designed the study|evaluated the data|performed the statistical analysis and drafted the manuscript	performed the statistical analysis and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5216001	28058674	TK	2	initiated and designed the study|coordinated the study and supervised the pet scans|evaluated the data|performed the statistical analysis and drafted the manuscript	initiated and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5216001	28058674	TK	2	initiated and designed the study|coordinated the study and supervised the pet scans|evaluated the data|performed the statistical analysis and drafted the manuscript	coordinated the study and supervised the pet scans	-	Project administration|Supervision	YES
5216001	28058674	TK	2	initiated and designed the study|coordinated the study and supervised the pet scans|evaluated the data|performed the statistical analysis and drafted the manuscript	evaluated the data	-	-	NO
5216001	28058674	TK	2	initiated and designed the study|coordinated the study and supervised the pet scans|evaluated the data|performed the statistical analysis and drafted the manuscript	performed the statistical analysis and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6340639	30814775	Amira Abadzic	2	contributed equally to the study conduct, collection of data, data processing, statistical analysis, writing the manuscript and checking the manuscript for important intellectual content	contributed equally to the study conduct, collection of data, data processing, statistical analysis, writing the manuscript and checking the manuscript for important intellectual content	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Data curation|Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
6340639	30814775	Amra Lasic	2	contributed equally to the study conduct, collection of data, data processing, statistical analysis, writing the manuscript and checking the manuscript for important intellectual content	contributed equally to the study conduct, collection of data, data processing, statistical analysis, writing the manuscript and checking the manuscript for important intellectual content	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Data curation|Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
6340639	30814775	Ana Ristic	2	contributed equally to the study conduct, collection of data, data processing, statistical analysis, writing the manuscript and checking the manuscript for important intellectual content	contributed equally to the study conduct, collection of data, data processing, statistical analysis, writing the manuscript and checking the manuscript for important intellectual content	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Data curation|Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
6340639	30814775	Azra Ibrahimovic	2	contributed equally to the study conduct, collection of data, data processing, statistical analysis, writing the manuscript and checking the manuscript for important intellectual content	contributed equally to the study conduct, collection of data, data processing, statistical analysis, writing the manuscript and checking the manuscript for important intellectual content	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Data curation|Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
6340639	30814775	Brankica Grujic	2	contributed equally to the study conduct, collection of data, data processing, statistical analysis, writing the manuscript and checking the manuscript for important intellectual content	contributed equally to the study conduct, collection of data, data processing, statistical analysis, writing the manuscript and checking the manuscript for important intellectual content	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Data curation|Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
6340639	30814775	Daniela Delic	2	contributed equally to the study conduct, collection of data, data processing, statistical analysis, writing the manuscript and checking the manuscript for important intellectual content	contributed equally to the study conduct, collection of data, data processing, statistical analysis, writing the manuscript and checking the manuscript for important intellectual content	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Data curation|Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
6340639	30814775	Danijela Blagojevic	2	contributed equally to the study conduct, collection of data, data processing, statistical analysis, writing the manuscript and checking the manuscript for important intellectual content	contributed equally to the study conduct, collection of data, data processing, statistical analysis, writing the manuscript and checking the manuscript for important intellectual content	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Data curation|Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
6340639	30814775	Dzemal Hajduk	2	contributed equally to the study conduct, collection of data, data processing, statistical analysis, writing the manuscript and checking the manuscript for important intellectual content	contributed equally to the study conduct, collection of data, data processing, statistical analysis, writing the manuscript and checking the manuscript for important intellectual content	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Data curation|Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
6340639	30814775	Edita Sopta	2	contributed equally to the study conduct, collection of data, data processing, statistical analysis, writing the manuscript and checking the manuscript for important intellectual content	contributed equally to the study conduct, collection of data, data processing, statistical analysis, writing the manuscript and checking the manuscript for important intellectual content	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Data curation|Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
6340639	30814775	Ema Hadzic	2	contributed equally to the study conduct, collection of data, data processing, statistical analysis, writing the manuscript and checking the manuscript for important intellectual content	contributed equally to the study conduct, collection of data, data processing, statistical analysis, writing the manuscript and checking the manuscript for important intellectual content	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Data curation|Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
6340639	30814775	Henrieta Hodzic	2	contributed equally to the study conduct, collection of data, data processing, statistical analysis, writing the manuscript and checking the manuscript for important intellectual content	contributed equally to the study conduct, collection of data, data processing, statistical analysis, writing the manuscript and checking the manuscript for important intellectual content	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Data curation|Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
6340639	30814775	Jasminka Jasic	2	contributed equally to the study conduct, collection of data, data processing, statistical analysis, writing the manuscript and checking the manuscript for important intellectual content	contributed equally to the study conduct, collection of data, data processing, statistical analysis, writing the manuscript and checking the manuscript for important intellectual content	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Data curation|Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
6340639	30814775	Marinela Djakovic	2	contributed equally to the study conduct, collection of data, data processing, statistical analysis, writing the manuscript and checking the manuscript for important intellectual content	contributed equally to the study conduct, collection of data, data processing, statistical analysis, writing the manuscript and checking the manuscript for important intellectual content	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Data curation|Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
6340639	30814775	Raifa Bajramovic	2	contributed equally to the study conduct, collection of data, data processing, statistical analysis, writing the manuscript and checking the manuscript for important intellectual content	contributed equally to the study conduct, collection of data, data processing, statistical analysis, writing the manuscript and checking the manuscript for important intellectual content	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Data curation|Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
6340639	30814775	Sadeta Ganic	2	contributed equally to the study conduct, collection of data, data processing, statistical analysis, writing the manuscript and checking the manuscript for important intellectual content	contributed equally to the study conduct, collection of data, data processing, statistical analysis, writing the manuscript and checking the manuscript for important intellectual content	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Data curation|Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
6340639	30814775	Slobodan M. Jankovic	2	contributed to the study design, conduct, data processing, statistical analysis, writing the manuscript and checking the manuscript for important intellectual content	contributed to the study design, conduct, data processing, statistical analysis, writing the manuscript and checking the manuscript for important intellectual content	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Data curation|Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
6340639	30814775	Snjezana Prcic Keric	2	contributed equally to the study conduct, collection of data, data processing, statistical analysis, writing the manuscript and checking the manuscript for important intellectual content	contributed equally to the study conduct, collection of data, data processing, statistical analysis, writing the manuscript and checking the manuscript for important intellectual content	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Data curation|Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
6340639	30814775	Zumra Solbi	2	contributed equally to the study conduct, collection of data, data processing, statistical analysis, writing the manuscript and checking the manuscript for important intellectual content	contributed equally to the study conduct, collection of data, data processing, statistical analysis, writing the manuscript and checking the manuscript for important intellectual content	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Data curation|Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5347174	28288557	AC	2	participated in the statistical analyses and helped to draft the manuscript	participated in the statistical analyses and helped to draft the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5347174	28288557	CMC	2	participated in the statistical analyses, wrote and revised the manuscript	participated in the statistical analyses, wrote and revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5347174	28288557	LD	2	conceived the study, carried out statistical analyses and coordinated the study	conceived the study, carried out statistical analyses and coordinated the study	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Project administration	YES
5146323	27931519	BK	2	conceptualized the study design and implementation, data review and manuscript development	conceptualized the study design and implementation, data review and manuscript development	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Writing - Review & Editing	YES
5146323	27931519	CG	2	contributed to the study design and implementation, and manuscript review	contributed to the study design and implementation, and manuscript review	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
5146323	27931519	CH	2	contributed to data analysis and manuscript review	contributed to data analysis and manuscript review	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5146323	27931519	JA	2	contributed to the study design and implementation, manuscript review and approval	contributed to the study design and implementation, manuscript review and approval	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
5146323	27931519	MC	2	contributed to the study design and implementation, manuscript review and approval	contributed to the study design and implementation, manuscript review and approval	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
5146323	27931519	MR	2	contributed to the study design, manuscript review and approval	contributed to the study design, manuscript review and approval	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5146323	27931519	MW	2	contributed to data analysis and manuscript review	contributed to data analysis and manuscript review	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5146323	27931519	ON	2	contributed to the study design and implementation, and manuscript review	contributed to the study design and implementation, and manuscript review	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
5146323	27931519	RN	2	contributed to the study design and implementation, and manuscript review	contributed to the study design and implementation, and manuscript review	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
5146323	27931519	SA	2	contributed to the study design and implementation, and manuscript review	contributed to the study design and implementation, and manuscript review	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
5146323	27931519	SB	2	contributed to the study design and implementation, and manuscript review	contributed to the study design and implementation, and manuscript review	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
5146323	27931519	SO	2	contributed to the study implementation and manuscript review	contributed to the study implementation and manuscript review	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5146323	27931519	SP	2	contributed to the study design and implementation, and manuscript review	contributed to the study design and implementation, and manuscript review	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
5146323	27931519	TC	2	contributed to data analysis and manuscript review	contributed to data analysis and manuscript review	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5146323	27931519	TN	2	contributed to the study implementation and manuscript review	contributed to the study implementation and manuscript review	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5146323	27931519	WB	2	contributed to the study design, manuscript review and approval	contributed to the study design, manuscript review and approval	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
4406717	25901726	GZ	PLoS5	Conceived and designed the experiments|Reagents	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406717	25901726	GZ	PLoS5	Conceived and designed the experiments|Reagents	Reagents	-	-	NO
4406717	25901726	HD	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4406717	25901726	HD	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4406717	25901726	HD	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Analysis tools	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406717	25901726	HD	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Analysis tools	Analysis tools	-	-	NO
4406717	25901726	JZ	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4406717	25901726	LZ	PLoS5	Performed the experiments|Wrote the paper|Materials	Performed the experiments	Performed the experiments	Investigation	YES
4406717	25901726	LZ	PLoS5	Performed the experiments|Wrote the paper|Materials	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406717	25901726	LZ	PLoS5	Performed the experiments|Wrote the paper|Materials	Materials	-	-	NO
4406717	25901726	QJ	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406717	25901726	QJ	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406717	25901726	QY	PLoS5	Performed the experiments|Materials	Performed the experiments	Performed the experiments	Investigation	YES
4406717	25901726	QY	PLoS5	Performed the experiments|Materials	Materials	-	-	NO
4406717	25901726	XX	PLoS5	Performed the experiments|Materials	Performed the experiments	Performed the experiments	Investigation	YES
4406717	25901726	XX	PLoS5	Performed the experiments|Materials	Materials	-	-	NO
4406717	25901726	XZ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Reagents	Performed the experiments	Performed the experiments	Investigation	YES
4406717	25901726	XZ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Reagents	Analyzed the data	Analyzed the data	Formal analysis	YES
4406717	25901726	XZ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Reagents	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406717	25901726	XZ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Reagents	Reagents	-	-	NO
4406717	25901726	YC	PLoS5	Analyzed the data|Analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4406717	25901726	YC	PLoS5	Analyzed the data|Analysis tools	Analysis tools	-	-	NO
4406717	25901726	ZQ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4406717	25901726	ZQ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4406717	25901726	ZQ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Analysis tools	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406717	25901726	ZQ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Analysis tools	Analysis tools	-	-	NO
4406717	25901726	ZR	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406717	25901726	ZR	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6120608	30181871	Ankush Golhar	7	Collected data in collaboration with the first author	Collected data in collaboration with the first author	Performed the experiments	Investigation	YES
6120608	30181871	N Mehta	7	Supervised the preparation of the manuscript. Did the first editing	Supervised the preparation of the manuscript. Did the first editing	Wrote the paper	Supervision|Writing - Original Draft|Writing - Review & Editing	YES
6120608	30181871	Samiran Nundy	7	Chief supervisor. Final correction and approval of the manuscript	Chief supervisor. Final correction and approval of the manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
6120608	30181871	Samrat Ray	7	Prepared the manuscript. Gathered all the data for preparing the review. Naimish	Prepared the manuscript. Gathered all the data for preparing the review. Naimish	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5574902	28890721	AM	2	assisted with field manipulation and natural population handling	assisted with field manipulation and natural population handling	Performed the experiments	Investigation	YES
5574902	28890721	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5574902	28890721	HW	2	conceptualized and coordinated the project and assisted in drafting the manuscript	conceptualized and coordinated the project and assisted in drafting the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Project administration|Writing - Original Draft	YES
5574902	28890721	JL	2	contributed to data interpretation and assisted in drafting the manuscript	contributed to data interpretation and assisted in drafting the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5574902	28890721	MM	2	contributed to data interpretation and assisted in drafting the manuscript	contributed to data interpretation and assisted in drafting the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5574902	28890721	RG	2	performed the experimental work and the statistical analysis, and contributed to drafting the manuscript	performed the experimental work and the statistical analysis, and contributed to drafting the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5574902	28890721	SJ	2	contributed to the statistical analysis	contributed to the statistical analysis	Analyzed the data	Formal analysis	YES
5574902	28890721	XY	2	conceptualized and coordinated the project and assisted in drafting the manuscript	conceptualized and coordinated the project and assisted in drafting the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Project administration|Writing - Original Draft	YES
5218957	28063068	AC	2	assisted with the acquisitions and analysis of data	assisted with the acquisitions and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5218957	28063068	JT	2	assisted with the acquisitions and analysis of data	assisted with the acquisitions and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5218957	28063068	MG	2	assisted with the acquisitions and analysis of data	assisted with the acquisitions and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5218957	28063068	PE	2	assisted with the acquisitions and analysis of data	assisted with the acquisitions and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5149708	27938646	AG	1	Sample management and processing|Clinical data collection and analysis	Sample management and processing	-	Data curation	YES
5149708	27938646	AG	1	Sample management and processing|Clinical data collection and analysis	Clinical data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5149708	27938646	AL	1	Flow cytometry panel design|Flow cytometry data acquisition and analysis	Flow cytometry panel design	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5149708	27938646	AL	1	Flow cytometry panel design|Flow cytometry data acquisition and analysis	Flow cytometry data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5149708	27938646	APT	1	Sample management and processing|Clinical data collection and analysis	Sample management and processing	-	Data curation	YES
5149708	27938646	APT	1	Sample management and processing|Clinical data collection and analysis	Clinical data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5149708	27938646	BDW	1	Study design|Critical scientific input and funding	Study design	Conceived and designed the experiments	Methodology	YES
5149708	27938646	BDW	1	Study design|Critical scientific input and funding	Critical scientific input and funding	-	Funding acquisition	YES
5149708	27938646	CDP	1	Sample management and processing|Clinical data collection and analysis|Study design|Flow cytometry panel design|Flow cytometry data acquisition and analysis|Data analysis and statistics	Sample management and processing	-	Data curation	YES
5149708	27938646	CDP	1	Sample management and processing|Clinical data collection and analysis|Study design|Flow cytometry panel design|Flow cytometry data acquisition and analysis|Data analysis and statistics	Clinical data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5149708	27938646	CDP	1	Sample management and processing|Clinical data collection and analysis|Study design|Flow cytometry panel design|Flow cytometry data acquisition and analysis|Data analysis and statistics	Study design	Conceived and designed the experiments	Methodology	YES
5149708	27938646	CDP	1	Sample management and processing|Clinical data collection and analysis|Study design|Flow cytometry panel design|Flow cytometry data acquisition and analysis|Data analysis and statistics	Flow cytometry panel design	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5149708	27938646	CDP	1	Sample management and processing|Clinical data collection and analysis|Study design|Flow cytometry panel design|Flow cytometry data acquisition and analysis|Data analysis and statistics	Flow cytometry data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5149708	27938646	CDP	1	Sample management and processing|Clinical data collection and analysis|Study design|Flow cytometry panel design|Flow cytometry data acquisition and analysis|Data analysis and statistics	Data analysis and statistics	Analyzed the data	Formal analysis	YES
5149708	27938646	EPS	1	Flow cytometry panel design|Flow cytometry data acquisition and analysis	Flow cytometry panel design	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5149708	27938646	EPS	1	Flow cytometry panel design|Flow cytometry data acquisition and analysis	Flow cytometry data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5149708	27938646	FP	1	Study design|Critical scientific input and funding	Study design	Conceived and designed the experiments	Methodology	YES
5149708	27938646	FP	1	Study design|Critical scientific input and funding	Critical scientific input and funding	-	Funding acquisition	YES
5149708	27938646	LBC	1	Data analysis and statistics	Data analysis and statistics	Analyzed the data	Formal analysis	YES
5149708	27938646	MRT	1	Sample management and processing|Clinical data collection and analysis|Flow cytometry data acquisition and analysis	Sample management and processing	-	Data curation	YES
5149708	27938646	MRT	1	Sample management and processing|Clinical data collection and analysis|Flow cytometry data acquisition and analysis	Clinical data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5149708	27938646	MRT	1	Sample management and processing|Clinical data collection and analysis|Flow cytometry data acquisition and analysis	Flow cytometry data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5149708	27938646	MSS	1	Determination of neutralizing antibody breadth	Determination of neutralizing antibody breadth	Performed the experiments	Investigation	YES
5149708	27938646	SJ	1	Study design|Critical scientific input and funding	Study design	Conceived and designed the experiments	Methodology	YES
5149708	27938646	SJ	1	Study design|Critical scientific input and funding	Critical scientific input and funding	-	Funding acquisition	YES
6122314	30186599	AA	7	critical, final review of the paper	critical, final review of the paper	Wrote the paper	Writing - Review & Editing	YES
6122314	30186599	BP	7	data gathering and review of the paper	data gathering and review of the paper	Wrote the paper	Writing - Review & Editing	YES
6122314	30186599	GI	7	critical review and writing of the paper	critical review and writing of the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6122314	30186599	GP	7	data gathering|data gathering and review of the paper	data gathering	-	-	NO
6122314	30186599	GP	7	data gathering|data gathering and review of the paper	data gathering and review of the paper	Wrote the paper	Writing - Review & Editing	YES
6122314	30186599	MS	7	data gathering	data gathering	-	-	NO
6122314	30186599	RP	7	data gathering and literature review	data gathering and literature review	-	Formal analysis	YES
5496502	28717459	A.M.	2	performed the experiments and analyzed data	performed the experiments and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5496502	28717459	B.L.	2	designed the research, performed the experiments and wrote the paper	designed the research, performed the experiments and wrote the paper	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5496502	28717459	C.P.	2	performed the animal experiments and histological analysis	performed the animal experiments and histological analysis	Performed the experiments	Investigation	YES
5496502	28717459	C.S.	2	designed the research, performed the experiments and wrote the paper	designed the research, performed the experiments and wrote the paper	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5496502	28717459	D.T.	2	guided the research and analyzed data	guided the research and analyzed data	Analyzed the data	Formal analysis|Supervision	YES
5496502	28717459	E.A.	2	performed the animal experiments and histological analysis	performed the animal experiments and histological analysis	Performed the experiments	Investigation	YES
5496502	28717459	H.D.	2	carried out total protein synthesis, purification and characterization	carried out total protein synthesis, purification and characterization	Performed the experiments	Investigation	YES
5496502	28717459	H.G.	2	provided recombinant nk1, analyzed data and wrote the paper	provided recombinant nk1, analyzed data and wrote the paper	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft	YES
5496502	28717459	J.M.	2	carried out native mass spectrometry analysis	carried out native mass spectrometry analysis	Performed the experiments	Investigation	YES
5496502	28717459	J.V.	2	conceived the project, guided the research, analyzed data and wrote the paper	conceived the project, guided the research, analyzed data and wrote the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Supervision|Writing - Original Draft	YES
5496502	28717459	L.R.	2	carried out total protein synthesis, purification and characterization	carried out total protein synthesis, purification and characterization	Performed the experiments	Investigation	YES
5496502	28717459	N.O.	2	carried out total protein synthesis, purification and characterization	carried out total protein synthesis, purification and characterization	Performed the experiments	Investigation	YES
5496502	28717459	O.M.	2	conceived the project, guided the research, analyzed data and wrote the paper	conceived the project, guided the research, analyzed data and wrote the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Supervision|Writing - Original Draft	YES
5496502	28717459	S.C.	2	carried out native mass spectrometry analysis	carried out native mass spectrometry analysis	Performed the experiments	Investigation	YES
5348779	28288562	AC	2	helped with the analysis and results interpretation	helped with the analysis and results interpretation	Analyzed the data	Formal analysis	YES
5348779	28288562	FSS	2	participated in the design of the study and data acquisition and were involved in the discussions	participated in the design of the study and data acquisition and were involved in the discussions	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5348779	28288562	JWK	2	participated in the design of the study and data acquisition and were involved in the discussions	participated in the design of the study and data acquisition and were involved in the discussions	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5348779	28288562	LFB	2	participated in the design of the study, carried out the analyses and results interpretation, was involved in the discussions, prepared and drafted the manuscript	participated in the design of the study, carried out the analyses and results interpretation, was involved in the discussions, prepared and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5348779	28288562	LRPN	2	participated in the design of the study and data acquisition and were involved in the discussions	participated in the design of the study and data acquisition and were involved in the discussions	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5348779	28288562	MJ	2	participated in the design of the study and data acquisition and were involved in the discussions	participated in the design of the study and data acquisition and were involved in the discussions	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5348779	28288562	MS	2	helped with the analysis and results interpretation	helped with the analysis and results interpretation	Analyzed the data	Formal analysis	YES
5348779	28288562	RVV	2	helped with the analysis and results interpretation	helped with the analysis and results interpretation	Analyzed the data	Formal analysis	YES
5348779	28288562	ZF	2	helped with the analysis and results interpretation	helped with the analysis and results interpretation	Analyzed the data	Formal analysis	YES
4406718	25902039	A-DG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4406718	25902039	BN	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4406718	25902039	MC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4406718	25902039	MP	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406718	25902039	MP	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406718	25902039	MP	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406718	25902039	NP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4406718	25902039	RJQ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406718	25902039	RJQ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406718	25902039	RJQ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5574904	28890725	BF	2	designed all of the experiments|wrote the manuscript	designed all of the experiments	Conceived and designed the experiments	Methodology	YES
5574904	28890725	BF	2	designed all of the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5574904	28890725	LC	2	designed all of the experiments|wrote the manuscript	designed all of the experiments	Conceived and designed the experiments	Methodology	YES
5574904	28890725	LC	2	designed all of the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5574904	28890725	WD	2	designed all of the experiments|wrote the manuscript	designed all of the experiments	Conceived and designed the experiments	Methodology	YES
5574904	28890725	WD	2	designed all of the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5574904	28890725	XL	2	designed all of the experiments|performed all the lab work and data analysis|wrote the manuscript	designed all of the experiments	Conceived and designed the experiments	Methodology	YES
5574904	28890725	XL	2	designed all of the experiments|performed all the lab work and data analysis|wrote the manuscript	performed all the lab work and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5574904	28890725	XL	2	designed all of the experiments|performed all the lab work and data analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5222763	28070731	EFA	2	participated in the study planning, data analysis and interpretation, and manuscript revising	participated in the study planning, data analysis and interpretation, and manuscript revising	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5222763	28070731	IS	2	carried out the study planning, data acquisition, data analysis and interpretation, and manuscript drafting	carried out the study planning, data acquisition, data analysis and interpretation, and manuscript drafting	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5222763	28070731	ROB	2	participated in the study planning, data analysis and interpretation, and manuscript revising	participated in the study planning, data analysis and interpretation, and manuscript revising	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5222763	28070731	VS	2	carried out the study planning, data acquisition, data analysis and interpretation, and manuscript drafting	carried out the study planning, data acquisition, data analysis and interpretation, and manuscript drafting	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
6122365	30186598	A Noorbhai	2	conceptualised and wrote the paper	conceptualised and wrote the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5155127	27964776	IW	2	refined the coding and themes	refined the coding and themes	-	-	NO
5155127	27964776	JMBrown	2	designed the study and developed the interview guide	designed the study and developed the interview guide	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5155127	27964776	JO	2	designed the study and developed the interview guide|refined the coding and themes	designed the study and developed the interview guide	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5155127	27964776	JO	2	designed the study and developed the interview guide|refined the coding and themes	refined the coding and themes	-	-	NO
5155127	27964776	MP	2	drafted the initial manuscript and all the co-authors provided feedback	drafted the initial manuscript and all the co-authors provided feedback	Wrote the paper	Writing - Original Draft	YES
5155127	27964776	RCP	2	conceived of the study|designed the study and developed the interview guide|drafted the initial manuscript and all the co-authors provided feedback	conceived of the study	Conceived and designed the experiments	Conceptualization	YES
5155127	27964776	RCP	2	conceived of the study|designed the study and developed the interview guide|drafted the initial manuscript and all the co-authors provided feedback	designed the study and developed the interview guide	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5155127	27964776	RCP	2	conceived of the study|designed the study and developed the interview guide|drafted the initial manuscript and all the co-authors provided feedback	drafted the initial manuscript and all the co-authors provided feedback	Wrote the paper	Writing - Original Draft	YES
2346461	18419809	SJM	2	were responsible for the entire manuscript	were responsible for the entire manuscript	-	-	NO
2346461	18419809	TJP	2	were responsible for the entire manuscript	were responsible for the entire manuscript	-	-	NO
4406721	25901996	CMB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406721	25901996	CMB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406721	25901996	CMB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406721	25901996	CME	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406721	25901996	CME	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406721	25901996	CME	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406721	25901996	CME	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406721	25901996	CME	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5574913	28890723	CM	7	Development of the system and preliminary experiment, final approval and agreement with all aspects of the work	Development of the system and preliminary experiment, final approval and agreement with all aspects of the work	Performed the experiments	Investigation|Methodology	YES
5574913	28890723	KP	7	Development of experiment, data collection, final approval and agreement with all aspects of the work	Development of experiment, data collection, final approval and agreement with all aspects of the work	Performed the experiments	Investigation	YES
5574913	28890723	MC-S	7	Data collection, analysis and interpretation, draft work commentaries and corrections, final approval and agreement with all aspects of the work	Data collection, analysis and interpretation, draft work commentaries and corrections, final approval and agreement with all aspects of the work	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5574913	28890723	MG-R	7	Data collection, analysis and interpretation, drafting the work, commentaries corrections, final approval, and agreement with all aspects of the work	Data collection, analysis and interpretation, drafting the work, commentaries corrections, final approval, and agreement with all aspects of the work	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5574913	28890723	MN-M	7	Development of the system and experiment, data collection, data analysis, interpretation of data from preliminary experiment, final approval and agreement with all aspects of the work	Development of the system and experiment, data collection, data analysis, interpretation of data from preliminary experiment, final approval and agreement with all aspects of the work	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5574913	28890723	SC	7	Contribution to the development of the experiment, draft correction and final approval and agreement with all aspects of the work	Contribution to the development of the experiment, draft correction and final approval and agreement with all aspects of the work	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5574913	28890723	SD	7	Substantial contributions to the conception and design of the experiments, interpretation of the data, draft corrections final approval and agreement with all aspects of the work	Substantial contributions to the conception and design of the experiments, interpretation of the data, draft corrections final approval and agreement with all aspects of the work	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
5236040	28084612	JOD	2	both designed the study|analyzed and interpreted the resulting data, and drafted and revised the manuscript	both designed the study	Conceived and designed the experiments	Methodology	YES
5236040	28084612	JOD	2	both designed the study|analyzed and interpreted the resulting data, and drafted and revised the manuscript	analyzed and interpreted the resulting data, and drafted and revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5236040	28084612	PET-CT	2	pet-mr scanning	pet-mr scanning	-	-	NO
5236040	28084612	PS	2	both designed the study|analyzed and interpreted the resulting data, and drafted and revised the manuscript	both designed the study	Conceived and designed the experiments	Methodology	YES
5236040	28084612	PS	2	both designed the study|analyzed and interpreted the resulting data, and drafted and revised the manuscript	analyzed and interpreted the resulting data, and drafted and revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5348804	28288583	BG	2	analyzed the sequencing data and designed the indel primers	analyzed the sequencing data and designed the indel primers	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5348804	28288583	CC	2	analyzed the sequencing data and designed the indel primers	analyzed the sequencing data and designed the indel primers	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5348804	28288583	FH	2	isolated the samples, performed the marker assays, and analyzed the marker data|conceived the study and critically reviewed the manuscript	isolated the samples, performed the marker assays, and analyzed the marker data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5348804	28288583	FH	2	isolated the samples, performed the marker assays, and analyzed the marker data|conceived the study and critically reviewed the manuscript	conceived the study and critically reviewed the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5348804	28288583	HL	2	conceived the study and critically reviewed the manuscript	conceived the study and critically reviewed the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5348804	28288583	HY	2	isolated the samples, performed the marker assays, and analyzed the marker data	isolated the samples, performed the marker assays, and analyzed the marker data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5348804	28288583	LY	2	conceived the study and critically reviewed the manuscript	conceived the study and critically reviewed the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5348804	28288583	MZ	2	conceived the study and critically reviewed the manuscript	conceived the study and critically reviewed the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5348804	28288583	XL	2	developed the f 2 and bc populations and wrote and revised the manuscript|analyzed the sequencing data and designed the indel primers	developed the f 2 and bc populations and wrote and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5348804	28288583	XL	2	developed the f 2 and bc populations and wrote and revised the manuscript|analyzed the sequencing data and designed the indel primers	analyzed the sequencing data and designed the indel primers	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5348804	28288583	YL	2	conceived the study and critically reviewed the manuscript	conceived the study and critically reviewed the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5348804	28288583	YZ	2	conceived the study and critically reviewed the manuscript	conceived the study and critically reviewed the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5348804	28288583	ZF	2	conceived the study and critically reviewed the manuscript	conceived the study and critically reviewed the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5348804	28288583	ZL	2	isolated the samples, performed the marker assays, and analyzed the marker data|conceived the study and critically reviewed the manuscript	isolated the samples, performed the marker assays, and analyzed the marker data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5348804	28288583	ZL	2	isolated the samples, performed the marker assays, and analyzed the marker data|conceived the study and critically reviewed the manuscript	conceived the study and critically reviewed the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
6123059	30186600	NM	7	data collection, literature search, final decision to publish	data collection, literature search, final decision to publish	Performed the experiments	Formal analysis|Investigation	YES
6123059	30186600	SS	7	Literature search, writing paper, final decision to publish	Literature search, writing paper, final decision to publish	Wrote the paper	Formal analysis|Writing - Original Draft	YES
6123059	30186600	TRB	7	Study concept or design, data collection, literature search, writing paper, final decision to publish	Study concept or design, data collection, literature search, writing paper, final decision to publish	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5159683	27978939	All	2	authors have reviewed successive drafts	authors have reviewed successive drafts	Wrote the paper	Writing - Original Draft	YES
5159683	27978939	DRH	2	authors have reviewed successive drafts	authors have reviewed successive drafts	Wrote the paper	Writing - Original Draft	YES
5159683	27978939	TS	2	authors have reviewed successive drafts	authors have reviewed successive drafts	Wrote the paper	Writing - Original Draft	YES
2412901	18505564	JI	2	conceived this article, carried out the included analyses, and wrote the paper	conceived this article, carried out the included analyses, and wrote the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
5329681	28286675	All authors	2	contributed to the preparation of the manuscript and all authors read and approved the final paper	contributed to the preparation of the manuscript and all authors read and approved the final paper	Wrote the paper	Writing - Original Draft	YES
5329681	28286675	Carl Blomqvist	2	helped with the interpretation of the results and with drafting of the paper	helped with the interpretation of the results and with drafting of the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5329681	28286675	Fredrik Warnberg	2	designed the overall study, coordinated the study, and helped draft and finalize the paper	designed the overall study, coordinated the study, and helped draft and finalize the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft|Writing - Review & Editing	YES
5329681	28286675	Goran Liljegren	2	helped with the interpretation of the results and with drafting of the paper	helped with the interpretation of the results and with drafting of the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5329681	28286675	Thomas Sollie	2	was involved in the pathology review and scoring|also updated the follow-up	was involved in the pathology review and scoring	Performed the experiments	Investigation	YES
5329681	28286675	Thomas Sollie	2	was involved in the pathology review and scoring|also updated the follow-up	also updated the follow-up	-	-	NO
5329681	28286675	Tibor Tot	2	helped with the interpretation of the results and with drafting of the paper	helped with the interpretation of the results and with drafting of the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5329681	28286675	Wenjing Zhou	2	was responsible for data analyses and paper preparation and editing	was responsible for data analyses and paper preparation and editing	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5575147	28890724	BH	PLoS52	conceived and designed the experiments|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5575147	28890724	BH	PLoS52	conceived and designed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5575147	28890724	CB	PLoS52	conceived and designed the experiments|conducted the experiments and analyzed the data|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5575147	28890724	CB	PLoS52	conceived and designed the experiments|conducted the experiments and analyzed the data|wrote the paper	conducted the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5575147	28890724	CB	PLoS52	conceived and designed the experiments|conducted the experiments and analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406723	25901747	AJ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4406723	25901747	BL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4406723	25901747	DS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4406723	25901747	EA	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406723	25901747	EA	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406723	25901747	EDC	PLoS5	Wrote the paper|Helped with segmentation	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406723	25901747	EDC	PLoS5	Wrote the paper|Helped with segmentation	Helped with segmentation	-	-	NO
4406723	25901747	EN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406723	25901747	EN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406723	25901747	EN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406723	25901747	EN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406723	25901747	IVO	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4406723	25901747	JW	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406723	25901747	KB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4406723	25901747	LMA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406723	25901747	LMA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406723	25901747	LMA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406723	25901747	MII	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406723	25901747	MII	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406723	25901747	MII	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406723	25901747	MII	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406723	25901747	NK	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406723	25901747	NM	PLoS5	Revised the segmentation	Revised the segmentation	Wrote the paper	Writing - Review & Editing	YES
4406723	25901747	WK	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6123062	30186601	SM	2	wrote this paper	wrote this paper	Wrote the paper	Writing - Original Draft	YES
5165083	27989271	AV	2	provided comments on first and subsequent drafts	provided comments on first and subsequent drafts	Wrote the paper	Writing - Original Draft	YES
5165083	27989271	CF	2	provided comments on first and subsequent drafts	provided comments on first and subsequent drafts	Wrote the paper	Writing - Original Draft	YES
5165083	27989271	CJ	2	provided comments on first and subsequent drafts	provided comments on first and subsequent drafts	Wrote the paper	Writing - Original Draft	YES
5165083	27989271	GH	2	provided comments on first and subsequent drafts	provided comments on first and subsequent drafts	Wrote the paper	Writing - Original Draft	YES
5165083	27989271	IM	2	provided comments on first and subsequent drafts	provided comments on first and subsequent drafts	Wrote the paper	Writing - Original Draft	YES
5165083	27989271	JS	2	provided comments on first and subsequent drafts	provided comments on first and subsequent drafts	Wrote the paper	Writing - Original Draft	YES
5165083	27989271	MD	2	provided comments on first and subsequent drafts	provided comments on first and subsequent drafts	Wrote the paper	Writing - Original Draft	YES
5165083	27989271	MR	2	provided comments on first and subsequent drafts	provided comments on first and subsequent drafts	Wrote the paper	Writing - Original Draft	YES
5165083	27989271	RB	2	developed the original and final draft	developed the original and final draft	Wrote the paper	Writing - Original Draft	YES
5165083	27989271	SD	2	provided comments on first and subsequent drafts	provided comments on first and subsequent drafts	Wrote the paper	Writing - Original Draft	YES
5165083	27989271	VM	2	provided comments on first and subsequent drafts	provided comments on first and subsequent drafts	Wrote the paper	Writing - Original Draft	YES
5236043	28091957	All authors	2	conceived the study and participated in its design|participated in the interpretation of the data	conceived the study and participated in its design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5236043	28091957	All authors	2	conceived the study and participated in its design|participated in the interpretation of the data	participated in the interpretation of the data	Analyzed the data	Formal analysis	YES
5236043	28091957	LPT	2	scanned the phantoms	scanned the phantoms	-	-	NO
5236043	28091957	OLM	2	produced the sphere phantoms|scanned the phantoms|carried out the data analyses and drafted the manuscript	produced the sphere phantoms	-	-	NO
5236043	28091957	OLM	2	produced the sphere phantoms|scanned the phantoms|carried out the data analyses and drafted the manuscript	scanned the phantoms	-	-	NO
5236043	28091957	OLM	2	produced the sphere phantoms|scanned the phantoms|carried out the data analyses and drafted the manuscript	carried out the data analyses and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5236043	28091957	PET	2	scanned the phantoms	scanned the phantoms	-	-	NO
5348809	28288568	GMP	2	participated in the acquisition of data|analyzed and interpreted the data|wrote the manuscript	participated in the acquisition of data	Performed the experiments	Investigation	YES
5348809	28288568	GMP	2	participated in the acquisition of data|analyzed and interpreted the data|wrote the manuscript	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5348809	28288568	GMP	2	participated in the acquisition of data|analyzed and interpreted the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5348809	28288568	JSG	2	conceived and designed the study|participated in the acquisition of data|analyzed and interpreted the data|wrote the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5348809	28288568	JSG	2	conceived and designed the study|participated in the acquisition of data|analyzed and interpreted the data|wrote the manuscript	participated in the acquisition of data	Performed the experiments	Investigation	YES
5348809	28288568	JSG	2	conceived and designed the study|participated in the acquisition of data|analyzed and interpreted the data|wrote the manuscript	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5348809	28288568	JSG	2	conceived and designed the study|participated in the acquisition of data|analyzed and interpreted the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5348809	28288568	LP	2	participated in the acquisition of data	participated in the acquisition of data	Performed the experiments	Investigation	YES
5348809	28288568	THH	2	conceived and designed the study|analyzed and interpreted the data|wrote the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5348809	28288568	THH	2	conceived and designed the study|analyzed and interpreted the data|wrote the manuscript	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5348809	28288568	THH	2	conceived and designed the study|analyzed and interpreted the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5348809	28288568	YW	2	conceived and designed the study|participated in the acquisition of data|analyzed and interpreted the data|wrote the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5348809	28288568	YW	2	conceived and designed the study|participated in the acquisition of data|analyzed and interpreted the data|wrote the manuscript	participated in the acquisition of data	Performed the experiments	Investigation	YES
5348809	28288568	YW	2	conceived and designed the study|participated in the acquisition of data|analyzed and interpreted the data|wrote the manuscript	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5348809	28288568	YW	2	conceived and designed the study|participated in the acquisition of data|analyzed and interpreted the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5348809	28288568	ZL	2	participated in the acquisition of data	participated in the acquisition of data	Performed the experiments	Investigation	YES
6125797	30191063	Ahmad Mardani	1	Design|Data analysis	Design	Conceived and designed the experiments	-	YES
6125797	30191063	Ahmad Mardani	1	Design|Data analysis	Data analysis	Analyzed the data	Formal analysis	YES
6125797	30191063	Hajar Ziaei Hezarjaribi	1	Design	Design	Conceived and designed the experiments	-	YES
6125797	30191063	Mahdi Fakhar	1	Design|Data analysis	Design	Conceived and designed the experiments	-	YES
6125797	30191063	Mahdi Fakhar	1	Design|Data analysis	Data analysis	Analyzed the data	Formal analysis	YES
5575782	28890722	AJ	2	designed the experiments|wrote and approved the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5575782	28890722	AJ	2	designed the experiments|wrote and approved the manuscript	wrote and approved the manuscript	Wrote the paper	Writing - Original Draft	YES
5575782	28890722	DU	2	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5575782	28890722	MT	2	designed the experiments|wrote and approved the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5575782	28890722	MT	2	designed the experiments|wrote and approved the manuscript	wrote and approved the manuscript	Wrote the paper	Writing - Original Draft	YES
5575782	28890722	MT-O	2	designed the experiments|wrote and approved the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5575782	28890722	MT-O	2	designed the experiments|wrote and approved the manuscript	wrote and approved the manuscript	Wrote the paper	Writing - Original Draft	YES
3816017	24222846	B. Seyoum	2	participated in designing study, data collection, statistical analysis, and paper preparation	participated in designing study, data collection, statistical analysis, and paper preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
3816017	24222846	H. Melkamu	2	participated in designing study, data collection, statistical analysis, and paper preparation	participated in designing study, data collection, statistical analysis, and paper preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
3816017	24222846	Y. Dessie	2	participated in designing study, data collection, statistical analysis, and paper preparation	participated in designing study, data collection, statistical analysis, and paper preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
4406725	25901735	AN	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4406725	25901735	AN	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4406725	25901735	AN	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406725	25901735	CA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406725	25901735	CA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4406725	25901735	CA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4406725	25901735	CA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406725	25901735	DH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406725	25901735	DH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4406725	25901735	DH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4406725	25901735	DH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406725	25901735	EH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406725	25901735	EH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406725	25901735	EH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406725	25901735	JA	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406725	25901735	JA	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406725	25901735	KL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406725	25901735	KL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406725	25901735	KL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406725	25901735	KL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406725	25901735	KL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406725	25901735	KW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406725	25901735	KW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406725	25901735	KW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406725	25901735	RW	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406725	25901735	RW	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5165084	27989270	All authors	2	certify that they have participated sufficiently in the writing of this article and take responsbility for the content included	certify that they have participated sufficiently in the writing of this article and take responsbility for the content included	Wrote the paper	Writing - Original Draft	YES
5241566	28101733	AH	2	performed the monte carlo modeling and data analysis	performed the monte carlo modeling and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5241566	28101733	ALG	2	conducted the trial and data gathering|performed the monte carlo modeling and data analysis	conducted the trial and data gathering	Performed the experiments	Investigation	YES
5241566	28101733	ALG	2	conducted the trial and data gathering|performed the monte carlo modeling and data analysis	performed the monte carlo modeling and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5241566	28101733	All authors	2	contributed equally to this work|discussed the results and implications and commented on the manuscript	contributed equally to this work	-	-	NO
5241566	28101733	All authors	2	contributed equally to this work|discussed the results and implications and commented on the manuscript	discussed the results and implications and commented on the manuscript	-	-	NO
5241566	28101733	DK	2	conducted the trial and data gathering|performed the monte carlo modeling and data analysis	conducted the trial and data gathering	Performed the experiments	Investigation	YES
5241566	28101733	DK	2	conducted the trial and data gathering|performed the monte carlo modeling and data analysis	performed the monte carlo modeling and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5241566	28101733	DP	2	conducted the trial and data gathering	conducted the trial and data gathering	Performed the experiments	Investigation	YES
5241566	28101733	DS	2	performed the monte carlo modeling and data analysis	performed the monte carlo modeling and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5241566	28101733	GG	2	conducted the trial and data gathering	conducted the trial and data gathering	Performed the experiments	Investigation	YES
5241566	28101733	JNB	2	conducted the trial and data gathering|performed the monte carlo modeling and data analysis	conducted the trial and data gathering	Performed the experiments	Investigation	YES
5241566	28101733	JNB	2	conducted the trial and data gathering|performed the monte carlo modeling and data analysis	performed the monte carlo modeling and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5241566	28101733	JYB	2	conducted the trial and data gathering	conducted the trial and data gathering	Performed the experiments	Investigation	YES
5241566	28101733	PC	2	conducted the trial and data gathering	conducted the trial and data gathering	Performed the experiments	Investigation	YES
5351109	28292259	CQ	2	conceived of the study and drafted the manuscript	conceived of the study and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5351109	28292259	FF	2	conceived of the study and drafted the manuscript	conceived of the study and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5351109	28292259	HZ	2	performed the data mining, bioinformatics	performed the data mining, bioinformatics	Analyzed the data	Formal analysis	YES
5351109	28292259	JL	2	contributed to interpretation and modification of the data and manuscript	contributed to interpretation and modification of the data and manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
5351109	28292259	KL	2	contributed to interpretation and modification of the data and manuscript	contributed to interpretation and modification of the data and manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
5351109	28292259	LJ	2	performed the data mining, bioinformatics	performed the data mining, bioinformatics	Analyzed the data	Formal analysis	YES
5351109	28292259	LW	2	performed the data mining, bioinformatics	performed the data mining, bioinformatics	Analyzed the data	Formal analysis	YES
5351109	28292259	RW	2	carried out reagents and the field experiments	carried out reagents and the field experiments	Performed the experiments	Investigation	YES
5351109	28292259	SL	2	carried out reagents and the field experiments	carried out reagents and the field experiments	Performed the experiments	Investigation	YES
5351109	28292259	XX	2	carried out reagents and the field experiments	carried out reagents and the field experiments	Performed the experiments	Investigation	YES
5351109	28292259	YL	2	performed the data mining, bioinformatics	performed the data mining, bioinformatics	Analyzed the data	Formal analysis	YES
5449747	28596921	Abdurrahman Mohammed	2	participated in the design of the study, data collection, and statistical analyses	participated in the design of the study, data collection, and statistical analyses	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5449747	28596921	Belayneh Anawte	2	participated in the design of the study, data collection, and statistical analyses	participated in the design of the study, data collection, and statistical analyses	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5449747	28596921	Gebru Gebremariyam	2	participated in the design of the study, data collection, and statistical analyses	participated in the design of the study, data collection, and statistical analyses	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5449747	28596921	Kalayu Birhane	2	participated in statistical analysis, conducted the literature search and review, and wrote the first draft manuscript	participated in statistical analysis, conducted the literature search and review, and wrote the first draft manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5449747	28596921	Miskir Alemayehu	2	participated in the design of the study, data collection, and statistical analyses	participated in the design of the study, data collection, and statistical analyses	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5449747	28596921	Ruth Daniel	2	participated in the design of the study, data collection, and statistical analyses	participated in the design of the study, data collection, and statistical analyses	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5449747	28596921	Semeneh Addis	2	participated in the design of the study, data collection, and statistical analyses	participated in the design of the study, data collection, and statistical analyses	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5449747	28596921	Teshome Worke	2	participated in the design of the study, data collection, and statistical analyses	participated in the design of the study, data collection, and statistical analyses	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5449747	28596921	Wassie Negash	2	participated in the design of the study, data collection, and statistical analyses	participated in the design of the study, data collection, and statistical analyses	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
4406729	25902071	CZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4406729	25902071	HX	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4406729	25902071	JH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406729	25902071	JH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406729	25902071	JH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406729	25902071	SS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406729	25902071	SS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406729	25902071	SS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406729	25902071	SY	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406729	25902071	WB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4406729	25902071	XW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4406729	25902071	Y. Liang	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4406729	25902071	Y. Lu	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4406729	25902071	Y. Lu	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4406729	25902071	YY	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4406729	25902071	ZL	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5581342	28894453	All authors	2	contributed to analysis and interpretation of results|have made substantial, direct and intellectual contribution to the work, and approved it for publication	contributed to analysis and interpretation of results	Analyzed the data	Formal analysis	YES
5581342	28894453	All authors	2	contributed to analysis and interpretation of results|have made substantial, direct and intellectual contribution to the work, and approved it for publication	have made substantial, direct and intellectual contribution to the work, and approved it for publication	-	-	NO
5581342	28894453	EO	2	provided reagents and materials|wrote the manuscript	provided reagents and materials	Contributed reagents/materials/analysis tools	Resources	YES
5581342	28894453	EO	2	provided reagents and materials|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5581342	28894453	FV	2	conceived and designed the work|provided reagents and materials	conceived and designed the work	Conceived and designed the experiments	Conceptualization	YES
5581342	28894453	FV	2	conceived and designed the work|provided reagents and materials	provided reagents and materials	Contributed reagents/materials/analysis tools	Resources	YES
5581342	28894453	GG	2	conceived and designed the work|wrote the manuscript	conceived and designed the work	Conceived and designed the experiments	Conceptualization	YES
5581342	28894453	GG	2	conceived and designed the work|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5581342	28894453	MP	2	conceived and designed the work|provided reagents and materials	conceived and designed the work	Conceived and designed the experiments	Conceptualization	YES
5581342	28894453	MP	2	conceived and designed the work|provided reagents and materials	provided reagents and materials	Contributed reagents/materials/analysis tools	Resources	YES
5581342	28894453	MR	2	contribute to histological evaluations|wrote the manuscript	contribute to histological evaluations	Performed the experiments	Investigation	YES
5581342	28894453	MR	2	contribute to histological evaluations|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5581342	28894453	MS	2	conceived and designed the work|provided reagents and materials|wrote the manuscript	conceived and designed the work	Conceived and designed the experiments	Conceptualization	YES
5581342	28894453	MS	2	conceived and designed the work|provided reagents and materials|wrote the manuscript	provided reagents and materials	Contributed reagents/materials/analysis tools	Resources	YES
5581342	28894453	MS	2	conceived and designed the work|provided reagents and materials|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5581342	28894453	MT	2	contribute to histological evaluations	contribute to histological evaluations	Performed the experiments	Investigation	YES
5581342	28894453	MV	2	conceived and designed the work|provided reagents and materials|wrote the manuscript	conceived and designed the work	Conceived and designed the experiments	Conceptualization	YES
5581342	28894453	MV	2	conceived and designed the work|provided reagents and materials|wrote the manuscript	provided reagents and materials	Contributed reagents/materials/analysis tools	Resources	YES
5581342	28894453	MV	2	conceived and designed the work|provided reagents and materials|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5581342	28894453	VF	2	conceived and designed the work|performed all the experiments|wrote the manuscript	conceived and designed the work	Conceived and designed the experiments	Conceptualization	YES
5581342	28894453	VF	2	conceived and designed the work|performed all the experiments|wrote the manuscript	performed all the experiments	Performed the experiments	Investigation	YES
5581342	28894453	VF	2	conceived and designed the work|performed all the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6125798	30191061	G Sorelli	7	Consultant lead and study design	Consultant lead and study design	Conceived and designed the experiments	Methodology	YES
6125798	30191061	G Thrumurthy	7	Data analysis guidance	Data analysis guidance	Analyzed the data	Formal analysis|Supervision	YES
6125798	30191061	N Seymour	7	First draft writing, data collection lead. Sri	First draft writing, data collection lead. Sri	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6125798	30191061	R Som	7	Writing, statistical analysis and project lead	Writing, statistical analysis and project lead	Analyzed the data|Wrote the paper	Formal analysis	YES
6125798	30191061	Shivani Joshi	7	data collection. Paolo	data collection. Paolo	Performed the experiments	Investigation	YES
6125798	30191061	Sophia Khattak	7	data collection	data collection	Performed the experiments	Investigation	YES
2442112	18559111	RP	2	wrote the manuscript in its entirety	wrote the manuscript in its entirety	Wrote the paper	Writing - Original Draft	YES
535340	15511299	Animal Science	2	was involved in the conceptualisation and writing	was involved in the conceptualisation and writing	Conceived and designed the experiments|Wrote the paper	Conceptualization	YES
535340	15511299	C.H.	2	was instrumental in the chip design and production	was instrumental in the chip design and production	Conceived and designed the experiments	-	YES
535340	15511299	D.H.	2	designed the cross-species primers and carried out the semi-quantitative rt pcr	designed the cross-species primers and carried out the semi-quantitative rt pcr	Conceived and designed the experiments|Performed the experiments	Investigation	YES
535340	15511299	J.A.	2	conceived the studys idea, designed and optimised the protocols, carried out the hybridisations and was pivotal in developing the analysis plan and writing the manuscript	conceived the studys idea, designed and optimised the protocols, carried out the hybridisations and was pivotal in developing the analysis plan and writing the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Writing - Original Draft	YES
535340	15511299	M.N.	2	designed the cross-species primers and carried out the semi-quantitative rt pcr	designed the cross-species primers and carried out the semi-quantitative rt pcr	Conceived and designed the experiments|Performed the experiments	Investigation	YES
535340	15511299	R.H.	2	developed the analysis plan, analysed the data and was pivotal in writing the manuscript	developed the analysis plan, analysed the data and was pivotal in writing the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
535340	15511299	W.W.	2	performed the initial image analysis	performed the initial image analysis	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
5267757	28127694	BV	2	conceived and designed the study|analyzed and interpreted the data	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5267757	28127694	BV	2	conceived and designed the study|analyzed and interpreted the data	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5267757	28127694	GM	2	conceived and designed the study|analyzed and interpreted the data|drafted the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5267757	28127694	GM	2	conceived and designed the study|analyzed and interpreted the data|drafted the manuscript	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5267757	28127694	GM	2	conceived and designed the study|analyzed and interpreted the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5267757	28127694	IK	2	helped write the paper	helped write the paper	Wrote the paper	Writing - Original Draft	YES
5267757	28127694	PF	2	helped write the paper|supervised the project	helped write the paper	Wrote the paper	Writing - Original Draft	YES
5267757	28127694	PF	2	helped write the paper|supervised the project	supervised the project	-	Supervision	YES
5267757	28127694	SV	2	helped write the paper	helped write the paper	Wrote the paper	Writing - Original Draft	YES
5267757	28127694	TG	2	analyzed and interpreted the data|critically reviewed the manuscript	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5267757	28127694	TG	2	analyzed and interpreted the data|critically reviewed the manuscript	critically reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5267757	28127694	ZW	2	analyzed and interpreted the data|critically reviewed the manuscript	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5267757	28127694	ZW	2	analyzed and interpreted the data|critically reviewed the manuscript	critically reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5581393	28894454	AD	2	tested plants for resistance to clubroot	tested plants for resistance to clubroot	Performed the experiments	Investigation	YES
5581393	28894454	All authors	2	reviewed the manuscript and approved the final draft	reviewed the manuscript and approved the final draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5581393	28894454	BG	2	tested plants for resistance to clubroot	tested plants for resistance to clubroot	Performed the experiments	Investigation	YES
5581393	28894454	FY	2	conceived of the study|drafted the manuscript	conceived of the study	Conceived and designed the experiments	Conceptualization	YES
5581393	28894454	FY	2	conceived of the study|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5581393	28894454	GP	2	conceived of the study|provided parental lines	conceived of the study	Conceived and designed the experiments	Conceptualization	YES
5581393	28894454	GP	2	conceived of the study|provided parental lines	provided parental lines	-	-	NO
5581393	28894454	KF	2	provided parental lines	provided parental lines	-	-	NO
5581393	28894454	MM	2	tested plants for resistance to clubroot	tested plants for resistance to clubroot	Performed the experiments	Investigation	YES
5581393	28894454	SNP	2	flanking sequences	flanking sequences	Performed the experiments	Investigation	YES
5581393	28894454	XL	2	tested plants for resistance to clubroot	tested plants for resistance to clubroot	Performed the experiments	Investigation	YES
5581393	28894454	ZH	2	performed gene mapping and analysis of kasp markers|tested plants for resistance to clubroot|drafted the manuscript	performed gene mapping and analysis of kasp markers	Performed the experiments	Investigation	YES
5581393	28894454	ZH	2	performed gene mapping and analysis of kasp markers|tested plants for resistance to clubroot|drafted the manuscript	tested plants for resistance to clubroot	Performed the experiments	Investigation	YES
5581393	28894454	ZH	2	performed gene mapping and analysis of kasp markers|tested plants for resistance to clubroot|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4406730	25902047	CC	PLoS5	Conceived and designed the experiments|Performed the experiments|Critical revision of the manuscript for important intellectual content	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406730	25902047	CC	PLoS5	Conceived and designed the experiments|Performed the experiments|Critical revision of the manuscript for important intellectual content	Performed the experiments	Performed the experiments	Investigation	YES
4406730	25902047	CC	PLoS5	Conceived and designed the experiments|Performed the experiments|Critical revision of the manuscript for important intellectual content	Critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4406730	25902047	CS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4406730	25902047	DM	PLoS5	Conceived and designed the experiments|Performed the experiments|Critical revision of the manuscript for important intellectual content	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406730	25902047	DM	PLoS5	Conceived and designed the experiments|Performed the experiments|Critical revision of the manuscript for important intellectual content	Performed the experiments	Performed the experiments	Investigation	YES
4406730	25902047	DM	PLoS5	Conceived and designed the experiments|Performed the experiments|Critical revision of the manuscript for important intellectual content	Critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4406730	25902047	EMC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Critical revision of the manuscript for important intellectual content	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406730	25902047	EMC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Critical revision of the manuscript for important intellectual content	Performed the experiments	Performed the experiments	Investigation	YES
4406730	25902047	EMC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Critical revision of the manuscript for important intellectual content	Analyzed the data	Analyzed the data	Formal analysis	YES
4406730	25902047	EMC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Critical revision of the manuscript for important intellectual content	Critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4406730	25902047	HRO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406730	25902047	HRO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406730	25902047	HRO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406730	25902047	HRO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406730	25902047	MM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Critical revision of the manuscript for important intellectual content	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406730	25902047	MM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Critical revision of the manuscript for important intellectual content	Performed the experiments	Performed the experiments	Investigation	YES
4406730	25902047	MM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Critical revision of the manuscript for important intellectual content	Analyzed the data	Analyzed the data	Formal analysis	YES
4406730	25902047	MM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Critical revision of the manuscript for important intellectual content	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406730	25902047	MM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Critical revision of the manuscript for important intellectual content	Critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4406730	25902047	SS	PLoS5	Critical revision of the manuscript for important intellectual content	Critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5485356	28695012	Ghaleb Goussous	2	shared first authorship	shared first authorship	-	-	NO
5485356	28695012	Sadaf Jafferbhoy	2	shared first authorship	shared first authorship	-	-	NO
6127871	30197784	HOSPITAL	2	they engaged in each operations together	they engaged in each operations together	Performed the experiments	Investigation	YES
6127871	30197784	SHIROYAMA	2	they engaged in each operations together	they engaged in each operations together	Performed the experiments	Investigation	YES
6127871	30197784	Takashi Ishibashi	2	is my supervisor and he checked my paper	is my supervisor and he checked my paper	Wrote the paper	Supervision|Writing - Review & Editing	YES
2504001	18662383	FS	2	wrote the manuscript in its entirety	wrote the manuscript in its entirety	Wrote the paper	Writing - Original Draft	YES
5581395	28894455	KK	1	Conceived and designed the study	Conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5581395	28894455	M-BW	1	Conceived and designed the study	Conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5581395	28894455	MA	1	Conceived and designed the study	Conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5581395	28894455	US	1	Conceived and designed the study	Conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5353786	28302063	DH	2	conceived of and designed the data analysis processes|drafted the manuscript	conceived of and designed the data analysis processes	Conceived and designed the experiments|Analyzed the data	Conceptualization|Data curation|Formal analysis	YES
5353786	28302063	DH	2	conceived of and designed the data analysis processes|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5353786	28302063	IO	2	conceived of and designed the data analysis processes|drafted the manuscript	conceived of and designed the data analysis processes	Conceived and designed the experiments|Analyzed the data	Conceptualization|Data curation|Formal analysis	YES
5353786	28302063	IO	2	conceived of and designed the data analysis processes|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5272851	28130765	AV	2	recruited and imaged database participants	recruited and imaged database participants	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Investigation|Software|Visualization	YES
5272851	28130765	All authors	2	reviewed and approved the final manuscript	reviewed and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5272851	28130765	CJ	2	recruited and imaged database participants	recruited and imaged database participants	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Investigation|Software|Visualization	YES
5272851	28130765	JB	2	recruited and imaged database participants	recruited and imaged database participants	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Investigation|Software|Visualization	YES
5272851	28130765	JCD	2	contributed to the design, recruitment, and writing of the manuscript	contributed to the design, recruitment, and writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5272851	28130765	KT	2	recruited and imaged database participants	recruited and imaged database participants	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Investigation|Software|Visualization	YES
5272851	28130765	LTB	2	contributed to the design, recruitment, and writing of the manuscript	contributed to the design, recruitment, and writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5272851	28130765	MCB	2	recruited and imaged database participants	recruited and imaged database participants	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Investigation|Software|Visualization	YES
5272851	28130765	MK	2	recruited and imaged database participants	recruited and imaged database participants	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Investigation|Software|Visualization	YES
5272851	28130765	PMK	2	recruited and imaged database participants	recruited and imaged database participants	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Investigation|Software|Visualization	YES
5272851	28130765	RdN	2	recruited and imaged database participants	recruited and imaged database participants	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Investigation|Software|Visualization	YES
5272851	28130765	SA-N	2	recruited and imaged database participants	recruited and imaged database participants	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Investigation|Software|Visualization	YES
5272851	28130765	SH	2	recruited and imaged database participants	recruited and imaged database participants	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Investigation|Software|Visualization	YES
5272851	28130765	TS	2	acquired all of the data for system characterisation	acquired all of the data for system characterisation	Performed the experiments	Investigation	YES
5272851	28130765	TVB	2	recruited and imaged database participants	recruited and imaged database participants	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Investigation|Software|Visualization	YES
5272851	28130765	UOA	2	recruited and imaged database participants	recruited and imaged database participants	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Investigation|Software|Visualization	YES
5461116	28361500	All authors	2	contributed to the conceptualization and formation of the content, provided feedback and edits to the commentary and the eventual finalization of the commentary|reviewed and approved the commentary	contributed to the conceptualization and formation of the content, provided feedback and edits to the commentary and the eventual finalization of the commentary	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5461116	28361500	All authors	2	contributed to the conceptualization and formation of the content, provided feedback and edits to the commentary and the eventual finalization of the commentary|reviewed and approved the commentary	reviewed and approved the commentary	-	-	NO
5461116	28361500	JM	2	led the coordination and initiated the formation of the commentary	led the coordination and initiated the formation of the commentary	Conceived and designed the experiments	Conceptualization|Project administration	YES
4406731	25902060	ISA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406731	25902060	ISA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406731	25902060	ISA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406731	25902060	ISA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406731	25902060	MFV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406731	25902060	MFV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406731	25902060	MFV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406731	25902060	MFV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406731	25902060	MSS	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406731	25902060	MSS	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406731	25902060	PHLC	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406731	25902060	PHLC	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406731	25902060	VS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4406731	25902060	VS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
6138978	30224948	Kiran Hilal	7	data collection, data analysis, writing	data collection, data analysis, writing	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation	YES
6138978	30224948	Masood Umer	7	study design, data analysis, writing	study design, data analysis, writing	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology	YES
6138978	30224948	Mujahid Jamil	7	data analysis, writing	data analysis, writing	Analyzed the data|Wrote the paper	Formal analysis	YES
6138978	30224948	Nasir Uddin	7	data collection, data analysis, writing	data collection, data analysis, writing	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation	YES
6138978	30224948	Salim Allana	7	study design, data collection, data analysis, writing	study design, data collection, data analysis, writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology	YES
6138978	30224948	Shahryar Noordin	7	study design, data collection, data analysis, writing	study design, data collection, data analysis, writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology	YES
2527574	18694496	AGR	2	attest that they have each made substantial contributions in drafting the manuscript and revising it critically for important intellectual content, that they have given final approval of the version to be published, and that they have participated sufficiently in the work to take public responsibility for appropriate portions of the content|have each read and approved the final manuscript	attest that they have each made substantial contributions in drafting the manuscript and revising it critically for important intellectual content, that they have given final approval of the version to be published, and that they have participated sufficiently in the work to take public responsibility for appropriate portions of the content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
2527574	18694496	AGR	2	attest that they have each made substantial contributions in drafting the manuscript and revising it critically for important intellectual content, that they have given final approval of the version to be published, and that they have participated sufficiently in the work to take public responsibility for appropriate portions of the content|have each read and approved the final manuscript	have each read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
2527574	18694496	JLM	2	attest that they have each made substantial contributions in drafting the manuscript and revising it critically for important intellectual content, that they have given final approval of the version to be published, and that they have participated sufficiently in the work to take public responsibility for appropriate portions of the content|have each read and approved the final manuscript	attest that they have each made substantial contributions in drafting the manuscript and revising it critically for important intellectual content, that they have given final approval of the version to be published, and that they have participated sufficiently in the work to take public responsibility for appropriate portions of the content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
2527574	18694496	JLM	2	attest that they have each made substantial contributions in drafting the manuscript and revising it critically for important intellectual content, that they have given final approval of the version to be published, and that they have participated sufficiently in the work to take public responsibility for appropriate portions of the content|have each read and approved the final manuscript	have each read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
2527574	18694496	JLV	2	attest that they have each made substantial contributions in drafting the manuscript and revising it critically for important intellectual content, that they have given final approval of the version to be published, and that they have participated sufficiently in the work to take public responsibility for appropriate portions of the content|have each read and approved the final manuscript	attest that they have each made substantial contributions in drafting the manuscript and revising it critically for important intellectual content, that they have given final approval of the version to be published, and that they have participated sufficiently in the work to take public responsibility for appropriate portions of the content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
2527574	18694496	JLV	2	attest that they have each made substantial contributions in drafting the manuscript and revising it critically for important intellectual content, that they have given final approval of the version to be published, and that they have participated sufficiently in the work to take public responsibility for appropriate portions of the content|have each read and approved the final manuscript	have each read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
2527574	18694496	MYR	2	attest that they have each made substantial contributions in drafting the manuscript and revising it critically for important intellectual content, that they have given final approval of the version to be published, and that they have participated sufficiently in the work to take public responsibility for appropriate portions of the content|have each read and approved the final manuscript	attest that they have each made substantial contributions in drafting the manuscript and revising it critically for important intellectual content, that they have given final approval of the version to be published, and that they have participated sufficiently in the work to take public responsibility for appropriate portions of the content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
2527574	18694496	MYR	2	attest that they have each made substantial contributions in drafting the manuscript and revising it critically for important intellectual content, that they have given final approval of the version to be published, and that they have participated sufficiently in the work to take public responsibility for appropriate portions of the content|have each read and approved the final manuscript	have each read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5353869	28302059	JJL	2	processed data and performed statistical analysis together|supervised this study	processed data and performed statistical analysis together	Analyzed the data	Data curation|Formal analysis	YES
5353869	28302059	JJL	2	processed data and performed statistical analysis together|supervised this study	supervised this study	-	Supervision	YES
5353869	28302059	RG	2	processed data and performed statistical analysis together|drafted the manuscript	processed data and performed statistical analysis together	Analyzed the data	Data curation|Formal analysis	YES
5353869	28302059	RG	2	processed data and performed statistical analysis together|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5581396	28894456	AF	2	conceived the project, analyzed the data, and interpreted the majority of the results|wrote the article with contributions from other co-authors	conceived the project, analyzed the data, and interpreted the majority of the results	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
5581396	28894456	AF	2	conceived the project, analyzed the data, and interpreted the majority of the results|wrote the article with contributions from other co-authors	wrote the article with contributions from other co-authors	Wrote the paper	Writing - Original Draft	YES
5581396	28894456	KS	2	designed and performed metabolite profiling and drafted the materials section	designed and performed metabolite profiling and drafted the materials section	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5581396	28894456	MI	2	conceived the project, analyzed the data, and interpreted the majority of the results|conducted glutathione quantification|wrote the article with contributions from other co-authors	conceived the project, analyzed the data, and interpreted the majority of the results	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
5581396	28894456	MI	2	conceived the project, analyzed the data, and interpreted the majority of the results|conducted glutathione quantification|wrote the article with contributions from other co-authors	conducted glutathione quantification	Performed the experiments	Investigation	YES
5581396	28894456	MI	2	conceived the project, analyzed the data, and interpreted the majority of the results|conducted glutathione quantification|wrote the article with contributions from other co-authors	wrote the article with contributions from other co-authors	Wrote the paper	Writing - Original Draft	YES
5581396	28894456	MK	2	conceived the project, analyzed the data, and interpreted the majority of the results|designed and performed metabolite profiling and drafted the materials section|wrote the article with contributions from other co-authors	conceived the project, analyzed the data, and interpreted the majority of the results	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
5581396	28894456	MK	2	conceived the project, analyzed the data, and interpreted the majority of the results|designed and performed metabolite profiling and drafted the materials section|wrote the article with contributions from other co-authors	designed and performed metabolite profiling and drafted the materials section	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5581396	28894456	MK	2	conceived the project, analyzed the data, and interpreted the majority of the results|designed and performed metabolite profiling and drafted the materials section|wrote the article with contributions from other co-authors	wrote the article with contributions from other co-authors	Wrote the paper	Writing - Original Draft	YES
5581396	28894456	MKo	2	designed and performed metabolite profiling and drafted the materials section	designed and performed metabolite profiling and drafted the materials section	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5581396	28894456	RN	2	designed and performed metabolite profiling and drafted the materials section	designed and performed metabolite profiling and drafted the materials section	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5581396	28894456	YO	2	designed and performed metabolite profiling and drafted the materials section	designed and performed metabolite profiling and drafted the materials section	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6139388	30224949	Each author	2	participated in writing the manuscript and all agreed to accept equal responsibility for the accuracy of the content of the paper	participated in writing the manuscript and all agreed to accept equal responsibility for the accuracy of the content of the paper	Wrote the paper	Writing - Original Draft	YES
5285289	28144857	All authors	2	revised the manuscript and approved the final manuscript	revised the manuscript and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5285289	28144857	DK	2	designed the study and analysed the data|drafted the manuscript	designed the study and analysed the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5285289	28144857	DK	2	designed the study and analysed the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5285289	28144857	JvD	2	designed the study and analysed the data	designed the study and analysed the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5285289	28144857	MGK	2	designed the study and analysed the data	designed the study and analysed the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5461117	28361499	MN	5	led the drafting of the editorial with substantial input from CC	led the drafting of the editorial with substantial input from CC	Wrote the paper	Writing - Original Draft	YES
5461117	28361499	SvdP	5	led the drafting of the editorial with substantial input from CC	led the drafting of the editorial with substantial input from CC	Wrote the paper	Writing - Original Draft	YES
4406732	25902304	AF	PLoS5	Acquisition of the data|Critical revision of the manuscript|Approval of the final version of the manuscript	Acquisition of the data	Performed the experiments	Investigation	YES
4406732	25902304	AF	PLoS5	Acquisition of the data|Critical revision of the manuscript|Approval of the final version of the manuscript	Critical revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4406732	25902304	AF	PLoS5	Acquisition of the data|Critical revision of the manuscript|Approval of the final version of the manuscript	Approval of the final version of the manuscript	-	-	NO
4406732	25902304	CW	PLoS5	Interpretation of the data|Critical revision of the manuscript|Approval of the final version of the manuscript	Interpretation of the data	Analyzed the data	Formal analysis	YES
4406732	25902304	CW	PLoS5	Interpretation of the data|Critical revision of the manuscript|Approval of the final version of the manuscript	Critical revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4406732	25902304	CW	PLoS5	Interpretation of the data|Critical revision of the manuscript|Approval of the final version of the manuscript	Approval of the final version of the manuscript	-	-	NO
4406732	25902304	HB	PLoS5	Conceived and designed the experiments|Acquisition of the data|Critical revision of the manuscript|Supervision of the study|Obtained funding|Approval of the final version of the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406732	25902304	HB	PLoS5	Conceived and designed the experiments|Acquisition of the data|Critical revision of the manuscript|Supervision of the study|Obtained funding|Approval of the final version of the manuscript	Acquisition of the data	Performed the experiments	Investigation	YES
4406732	25902304	HB	PLoS5	Conceived and designed the experiments|Acquisition of the data|Critical revision of the manuscript|Supervision of the study|Obtained funding|Approval of the final version of the manuscript	Critical revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4406732	25902304	HB	PLoS5	Conceived and designed the experiments|Acquisition of the data|Critical revision of the manuscript|Supervision of the study|Obtained funding|Approval of the final version of the manuscript	Supervision of the study	-	Supervision	YES
4406732	25902304	HB	PLoS5	Conceived and designed the experiments|Acquisition of the data|Critical revision of the manuscript|Supervision of the study|Obtained funding|Approval of the final version of the manuscript	Obtained funding	-	Funding acquisition	YES
4406732	25902304	HB	PLoS5	Conceived and designed the experiments|Acquisition of the data|Critical revision of the manuscript|Supervision of the study|Obtained funding|Approval of the final version of the manuscript	Approval of the final version of the manuscript	-	-	NO
4406732	25902304	JK	PLoS5	Interpretation of the data|Critical revision of the manuscript|Approval of the final version of the manuscript	Interpretation of the data	Analyzed the data	Formal analysis	YES
4406732	25902304	JK	PLoS5	Interpretation of the data|Critical revision of the manuscript|Approval of the final version of the manuscript	Critical revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4406732	25902304	JK	PLoS5	Interpretation of the data|Critical revision of the manuscript|Approval of the final version of the manuscript	Approval of the final version of the manuscript	-	-	NO
4406732	25902304	MBS	PLoS5	Conceived and designed the experiments|Interpretation of the data|Critical revision of the manuscript|Supervision of the study|Obtained funding|Approval of the final version of the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406732	25902304	MBS	PLoS5	Conceived and designed the experiments|Interpretation of the data|Critical revision of the manuscript|Supervision of the study|Obtained funding|Approval of the final version of the manuscript	Interpretation of the data	Analyzed the data	Formal analysis	YES
4406732	25902304	MBS	PLoS5	Conceived and designed the experiments|Interpretation of the data|Critical revision of the manuscript|Supervision of the study|Obtained funding|Approval of the final version of the manuscript	Critical revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4406732	25902304	MBS	PLoS5	Conceived and designed the experiments|Interpretation of the data|Critical revision of the manuscript|Supervision of the study|Obtained funding|Approval of the final version of the manuscript	Supervision of the study	-	Supervision	YES
4406732	25902304	MBS	PLoS5	Conceived and designed the experiments|Interpretation of the data|Critical revision of the manuscript|Supervision of the study|Obtained funding|Approval of the final version of the manuscript	Obtained funding	-	Funding acquisition	YES
4406732	25902304	MBS	PLoS5	Conceived and designed the experiments|Interpretation of the data|Critical revision of the manuscript|Supervision of the study|Obtained funding|Approval of the final version of the manuscript	Approval of the final version of the manuscript	-	-	NO
4406732	25902304	NS	PLoS5	Interpretation of the data|Critical revision of the manuscript|Approval of the final version of the manuscript	Interpretation of the data	Analyzed the data	Formal analysis	YES
4406732	25902304	NS	PLoS5	Interpretation of the data|Critical revision of the manuscript|Approval of the final version of the manuscript	Critical revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4406732	25902304	NS	PLoS5	Interpretation of the data|Critical revision of the manuscript|Approval of the final version of the manuscript	Approval of the final version of the manuscript	-	-	NO
4406732	25902304	S. Jacobs	PLoS5	Interpretation of the data|Critical revision of the manuscript|Approval of the final version of the manuscript	Interpretation of the data	Analyzed the data	Formal analysis	YES
4406732	25902304	S. Jacobs	PLoS5	Interpretation of the data|Critical revision of the manuscript|Approval of the final version of the manuscript	Critical revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4406732	25902304	S. Jacobs	PLoS5	Interpretation of the data|Critical revision of the manuscript|Approval of the final version of the manuscript	Approval of the final version of the manuscript	-	-	NO
4406732	25902304	S. Jager	PLoS5	Analyzed the data|Wrote the paper|Interpretation of the data|Approval of the final version of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4406732	25902304	S. Jager	PLoS5	Analyzed the data|Wrote the paper|Interpretation of the data|Approval of the final version of the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406732	25902304	S. Jager	PLoS5	Analyzed the data|Wrote the paper|Interpretation of the data|Approval of the final version of the manuscript	Interpretation of the data	Analyzed the data	Formal analysis	YES
4406732	25902304	S. Jager	PLoS5	Analyzed the data|Wrote the paper|Interpretation of the data|Approval of the final version of the manuscript	Approval of the final version of the manuscript	-	-	NO
5632870	29147583	Patrick Kelly	2	contributed equally to this work	contributed equally to this work	-	-	NO
5632870	29147583	Zhe Ma	2	contributed equally to this work	contributed equally to this work	-	-	NO
2561033	18817568	ALH	2	conceived this papers topic, and all authors participated in the coordination of reviewed materials and helped draft the manuscript	conceived this papers topic, and all authors participated in the coordination of reviewed materials and helped draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Project administration|Writing - Original Draft|Writing - Review & Editing	YES
6141696	30245814	all authors	2	agreed upon their inclusion	agreed upon their inclusion	-	-	NO
6141696	30245814	all the authors	2	who also bear responsibility for it	who also bear responsibility for it	-	-	NO
5311016	28205113	All authors	2	gave the final approval of the version to be published	gave the final approval of the version to be published	-	-	NO
5311016	28205113	GA	2	carried out the data analysis and interpretation of the data, drafted the manuscript	carried out the data analysis and interpretation of the data, drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5311016	28205113	JAPJ	2	participated to the conceived of the study, participated in its design and coordination, and revised the manuscript critically	participated to the conceived of the study, participated in its design and coordination, and revised the manuscript critically	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Review & Editing	YES
5311016	28205113	JOP	2	conceived the study, participated in its design and coordination, and revised the manuscript critically as well as the resubmitted manuscript	conceived the study, participated in its design and coordination, and revised the manuscript critically as well as the resubmitted manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Review & Editing	YES
5311016	28205113	LV	2	participated to the conceived of the study and revised the manuscript critically	participated to the conceived of the study and revised the manuscript critically	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5311016	28205113	MSM	2	carried out the interpretation of the data, helped draft the manuscript revising it critically	carried out the interpretation of the data, helped draft the manuscript revising it critically	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5311016	28205113	PC	2	carried out the data acquisition analysis and interpretation of the data, drafted the manuscript first version	carried out the data acquisition analysis and interpretation of the data, drafted the manuscript first version	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5311016	28205113	SG	2	carried out the data analysis and interpretation of the data, drafted the manuscript	carried out the data analysis and interpretation of the data, drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5356301	28302071	CV	2	planned and designed experiments, analyzed and interpreted data, and wrote the manuscript together|oversaw and advised on the computational analysis of rna seq data	planned and designed experiments, analyzed and interpreted data, and wrote the manuscript together	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
5356301	28302071	CV	2	planned and designed experiments, analyzed and interpreted data, and wrote the manuscript together|oversaw and advised on the computational analysis of rna seq data	oversaw and advised on the computational analysis of rna seq data	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Supervision	YES
5356301	28302071	JLB	2	planned and designed experiments, analyzed and interpreted data, and wrote the manuscript together|performed computational analyses of rna seq and proteomics datasets, maintained the mouse colony, collected tissue, and prepared cdna libraries and protein extracts	planned and designed experiments, analyzed and interpreted data, and wrote the manuscript together	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
5356301	28302071	JLB	2	planned and designed experiments, analyzed and interpreted data, and wrote the manuscript together|performed computational analyses of rna seq and proteomics datasets, maintained the mouse colony, collected tissue, and prepared cdna libraries and protein extracts	performed computational analyses of rna seq and proteomics datasets, maintained the mouse colony, collected tissue, and prepared cdna libraries and protein extracts	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5356301	28302071	RSN	2	planned and designed experiments, analyzed and interpreted data, and wrote the manuscript together	planned and designed experiments, analyzed and interpreted data, and wrote the manuscript together	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
5581504	28894457	All three authors	2	have edited and revised the approved manuscript submitted	have edited and revised the approved manuscript submitted	Wrote the paper	Writing - Review & Editing	YES
5581504	28894457	SN	2	have helped in compilation of manuscript|contributed equally in this manuscript	have helped in compilation of manuscript	-	-	NO
5581504	28894457	SN	2	have helped in compilation of manuscript|contributed equally in this manuscript	contributed equally in this manuscript	-	-	NO
5581504	28894457	WS	2	has compiled the literature and written the manuscript|contributed equally in this manuscript	has compiled the literature and written the manuscript	Wrote the paper	Writing - Original Draft	YES
5581504	28894457	WS	2	has compiled the literature and written the manuscript|contributed equally in this manuscript	contributed equally in this manuscript	-	-	NO
5581504	28894457	ZA	2	has initiated and supervised the research|have helped in compilation of manuscript	has initiated and supervised the research	Conceived and designed the experiments	Conceptualization|Supervision	YES
5581504	28894457	ZA	2	has initiated and supervised the research|have helped in compilation of manuscript	have helped in compilation of manuscript	-	-	NO
2569955	18823539	MM	2	is responsible for the entire manuscript	is responsible for the entire manuscript	-	-	NO
4406733	25901992	CL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406733	25901992	CL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4406733	25901992	CL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4406733	25901992	HFZ	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406733	25901992	HFZ	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406733	25901992	JZZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406733	25901992	JZZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406733	25901992	JZZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406733	25901992	JZZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406733	25901992	JZZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406733	25901992	QPL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4406733	25901992	QPL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406733	25901992	RNS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4406733	25901992	RNS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406733	25901992	XFT	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
6143753	30237880	Angela Inviati	7	study concept or design, data collection	study concept or design, data collection	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
6143753	30237880	Domenico Massimo Pellegrino	7	review of study	review of study	-	-	NO
6143753	30237880	Domenico Schifano	7	data collection, writing the paper	data collection, writing the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5581827	28900438	All authors	2	agreed on the manuscript	agreed on the manuscript	-	-	NO
5581827	28900438	J-PJ	2	performed the experiments and analyzed data	performed the experiments and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5581827	28900438	MY	2	conceived and designed the research|performed the experiments and analyzed data|wrote the manuscript	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5581827	28900438	MY	2	conceived and designed the research|performed the experiments and analyzed data|wrote the manuscript	performed the experiments and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5581827	28900438	MY	2	conceived and designed the research|performed the experiments and analyzed data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5581827	28900438	SX	2	conceived and designed the research|wrote the manuscript	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5581827	28900438	SX	2	conceived and designed the research|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5581827	28900438	X-PC	2	provided technical assistance	provided technical assistance	Performed the experiments	Investigation	YES
5581827	28900438	XX	2	wrote the manuscript|supervised specific experiments	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5581827	28900438	XX	2	wrote the manuscript|supervised specific experiments	supervised specific experiments	-	Supervision	YES
5581827	28900438	Y-DC	2	designed the cell disruptor|provided technical assistance	designed the cell disruptor	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5581827	28900438	Y-DC	2	designed the cell disruptor|provided technical assistance	provided technical assistance	Performed the experiments	Investigation	YES
5581827	28900438	YF	2	participated in algal cultivation	participated in algal cultivation	-	-	NO
5581827	28900438	Z-YC	2	supervised specific experiments	supervised specific experiments	-	Supervision	YES
5313498	28211032	ADG	2	have coordinated the project and revised the manuscript	have coordinated the project and revised the manuscript	Wrote the paper	Project administration|Writing - Review & Editing	YES
5313498	28211032	BL	2	have contributed to the realization of the sipm matrices and to the preliminary tests	have contributed to the realization of the sipm matrices and to the preliminary tests	-	-	NO
5313498	28211032	FB	2	have participated to the realization of the experimental setup	have participated to the realization of the experimental setup	Performed the experiments	Investigation	YES
5313498	28211032	FP	2	has contributed to the realization of the simulation of the distribution of the crystal background|have participated in the development of the data analysis method|have contributed to the data acquisition and elaboration	has contributed to the realization of the simulation of the distribution of the crystal background	-	Formal analysis	YES
5313498	28211032	FP	2	has contributed to the realization of the simulation of the distribution of the crystal background|have participated in the development of the data analysis method|have contributed to the data acquisition and elaboration	have participated in the development of the data analysis method	Performed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5313498	28211032	FP	2	has contributed to the realization of the simulation of the distribution of the crystal background|have participated in the development of the data analysis method|have contributed to the data acquisition and elaboration	have contributed to the data acquisition and elaboration	Performed the experiments	Investigation	YES
5313498	28211032	GA	2	have contributed to the realization of the sipm matrices and to the preliminary tests	have contributed to the realization of the sipm matrices and to the preliminary tests	-	-	NO
5313498	28211032	GP	2	have participated to the realization of the experimental setup|have participated in the development of the data analysis method|have contributed to the data acquisition and elaboration	have participated to the realization of the experimental setup	Performed the experiments	Investigation	YES
5313498	28211032	GP	2	have participated to the realization of the experimental setup|have participated in the development of the data analysis method|have contributed to the data acquisition and elaboration	have participated in the development of the data analysis method	Performed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5313498	28211032	GP	2	have participated to the realization of the experimental setup|have participated in the development of the data analysis method|have contributed to the data acquisition and elaboration	have contributed to the data acquisition and elaboration	Performed the experiments	Investigation	YES
5313498	28211032	MAP	2	have worked at the realization of the acquisition system, at the optimization of the acquisition parameters, and at the realization of acquisition software|have contributed to the data acquisition and elaboration	have worked at the realization of the acquisition system, at the optimization of the acquisition parameters, and at the realization of acquisition software	Performed the experiments|Contributed reagents/materials/analysis tools	Software	YES
5313498	28211032	MAP	2	have worked at the realization of the acquisition system, at the optimization of the acquisition parameters, and at the realization of acquisition software|have contributed to the data acquisition and elaboration	have contributed to the data acquisition and elaboration	Performed the experiments	Investigation	YES
5313498	28211032	MB	2	have participated in the development of the data analysis method|have participated in the development of the data analysis method|have coordinated the project and revised the manuscript	have participated in the development of the data analysis method	Performed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5313498	28211032	MB	2	have participated in the development of the data analysis method|have participated in the development of the data analysis method|have coordinated the project and revised the manuscript	have participated in the development of the data analysis method	Performed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5313498	28211032	MB	2	have participated in the development of the data analysis method|have participated in the development of the data analysis method|have coordinated the project and revised the manuscript	have coordinated the project and revised the manuscript	Wrote the paper	Project administration|Writing - Review & Editing	YES
5313498	28211032	MI	2	have contributed to the realization of the sipm matrices and to the preliminary tests	have contributed to the realization of the sipm matrices and to the preliminary tests	-	-	NO
5313498	28211032	MM	2	have worked at the realization of the acquisition system, at the optimization of the acquisition parameters, and at the realization of acquisition software|have participated in the development of the data analysis method|have contributed to the data acquisition and elaboration	have worked at the realization of the acquisition system, at the optimization of the acquisition parameters, and at the realization of acquisition software	Performed the experiments|Contributed reagents/materials/analysis tools	Software	YES
5313498	28211032	MM	2	have worked at the realization of the acquisition system, at the optimization of the acquisition parameters, and at the realization of acquisition software|have participated in the development of the data analysis method|have contributed to the data acquisition and elaboration	have participated in the development of the data analysis method	Performed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5313498	28211032	MM	2	have worked at the realization of the acquisition system, at the optimization of the acquisition parameters, and at the realization of acquisition software|have participated in the development of the data analysis method|have contributed to the data acquisition and elaboration	have contributed to the data acquisition and elaboration	Performed the experiments	Investigation	YES
5313498	28211032	PC	2	have participated in the development of the data analysis method|have coordinated the project and revised the manuscript	have participated in the development of the data analysis method	Performed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5313498	28211032	PC	2	have participated in the development of the data analysis method|have coordinated the project and revised the manuscript	have coordinated the project and revised the manuscript	Wrote the paper	Project administration|Writing - Review & Editing	YES
5313498	28211032	RW	2	have worked at the realization of the acquisition system, at the optimization of the acquisition parameters, and at the realization of acquisition software|have participated in the development of the data analysis method	have worked at the realization of the acquisition system, at the optimization of the acquisition parameters, and at the realization of acquisition software	Performed the experiments|Contributed reagents/materials/analysis tools	Software	YES
5313498	28211032	RW	2	have worked at the realization of the acquisition system, at the optimization of the acquisition parameters, and at the realization of acquisition software|have participated in the development of the data analysis method	have participated in the development of the data analysis method	Performed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5313498	28211032	VP	2	have contributed to the realization of the sipm matrices and to the preliminary tests	have contributed to the realization of the sipm matrices and to the preliminary tests	-	-	NO
5461119	28364566	AC	PLoS52	led the study implementation in their respective countries, including choice of sampling strategy, local adaptations to the questionnaire, and organisation and quality control of data collection	led the study implementation in their respective countries, including choice of sampling strategy, local adaptations to the questionnaire, and organisation and quality control of data collection	Performed the experiments	Investigation|Validation	YES
5461119	28364566	AW	PLoS52	planned and designed the study|wrote the survey instrument|wrote the initial draft of the paper	planned and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5461119	28364566	AW	PLoS52	planned and designed the study|wrote the survey instrument|wrote the initial draft of the paper	wrote the survey instrument	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5461119	28364566	AW	PLoS52	planned and designed the study|wrote the survey instrument|wrote the initial draft of the paper	wrote the initial draft of the paper	Wrote the paper	Writing - Original Draft	YES
5461119	28364566	All authors	PLoS52	reviewed the paper and provided comments and inputs	reviewed the paper and provided comments and inputs	Wrote the paper	Writing - Review & Editing	YES
5461119	28364566	All other authors	PLoS52	reviewed the survey instrument and study protocol	reviewed the survey instrument and study protocol	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5461119	28364566	BN	PLoS52	led data entry for eight sites and performed initial data quality checks	led data entry for eight sites and performed initial data quality checks	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5461119	28364566	BZ	PLoS52	planned and designed the study	planned and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5461119	28364566	CN	PLoS52	led the study implementation in their respective countries, including choice of sampling strategy, local adaptations to the questionnaire, and organisation and quality control of data collection|coordinated data entry in their countries	led the study implementation in their respective countries, including choice of sampling strategy, local adaptations to the questionnaire, and organisation and quality control of data collection	Performed the experiments	Investigation|Validation	YES
5461119	28364566	CN	PLoS52	led the study implementation in their respective countries, including choice of sampling strategy, local adaptations to the questionnaire, and organisation and quality control of data collection|coordinated data entry in their countries	coordinated data entry in their countries	Analyzed the data	Data curation|Project administration	YES
5461119	28364566	DM	PLoS52	led the study implementation in their respective countries, including choice of sampling strategy, local adaptations to the questionnaire, and organisation and quality control of data collection	led the study implementation in their respective countries, including choice of sampling strategy, local adaptations to the questionnaire, and organisation and quality control of data collection	Performed the experiments	Investigation|Validation	YES
5461119	28364566	FXGO	PLoS52	led the study implementation in their respective countries, including choice of sampling strategy, local adaptations to the questionnaire, and organisation and quality control of data collection	led the study implementation in their respective countries, including choice of sampling strategy, local adaptations to the questionnaire, and organisation and quality control of data collection	Performed the experiments	Investigation|Validation	YES
5461119	28364566	GN	PLoS52	led the study implementation in their respective countries, including choice of sampling strategy, local adaptations to the questionnaire, and organisation and quality control of data collection	led the study implementation in their respective countries, including choice of sampling strategy, local adaptations to the questionnaire, and organisation and quality control of data collection	Performed the experiments	Investigation|Validation	YES
5461119	28364566	JM	PLoS52	led the study implementation in their respective countries, including choice of sampling strategy, local adaptations to the questionnaire, and organisation and quality control of data collection	led the study implementation in their respective countries, including choice of sampling strategy, local adaptations to the questionnaire, and organisation and quality control of data collection	Performed the experiments	Investigation|Validation	YES
5461119	28364566	JN	PLoS52	led the study implementation in their respective countries, including choice of sampling strategy, local adaptations to the questionnaire, and organisation and quality control of data collection	led the study implementation in their respective countries, including choice of sampling strategy, local adaptations to the questionnaire, and organisation and quality control of data collection	Performed the experiments	Investigation|Validation	YES
5461119	28364566	JT	PLoS52	planned and designed the study|wrote the survey instrument|wrote the initial draft of the paper	planned and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5461119	28364566	JT	PLoS52	planned and designed the study|wrote the survey instrument|wrote the initial draft of the paper	wrote the survey instrument	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5461119	28364566	JT	PLoS52	planned and designed the study|wrote the survey instrument|wrote the initial draft of the paper	wrote the initial draft of the paper	Wrote the paper	Writing - Original Draft	YES
5461119	28364566	KC	PLoS52	planned and designed the study|designed the conceptual framework and undertook the literature review to guide instrument design|wrote the survey instrument|analysed the data|wrote the initial draft of the paper|finalized the paper	planned and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5461119	28364566	KC	PLoS52	planned and designed the study|designed the conceptual framework and undertook the literature review to guide instrument design|wrote the survey instrument|analysed the data|wrote the initial draft of the paper|finalized the paper	designed the conceptual framework and undertook the literature review to guide instrument design	Conceived and designed the experiments|Performed the experiments	Conceptualization|Formal analysis|Investigation	YES
5461119	28364566	KC	PLoS52	planned and designed the study|designed the conceptual framework and undertook the literature review to guide instrument design|wrote the survey instrument|analysed the data|wrote the initial draft of the paper|finalized the paper	wrote the survey instrument	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5461119	28364566	KC	PLoS52	planned and designed the study|designed the conceptual framework and undertook the literature review to guide instrument design|wrote the survey instrument|analysed the data|wrote the initial draft of the paper|finalized the paper	analysed the data	Analyzed the data	Formal analysis	YES
5461119	28364566	KC	PLoS52	planned and designed the study|designed the conceptual framework and undertook the literature review to guide instrument design|wrote the survey instrument|analysed the data|wrote the initial draft of the paper|finalized the paper	wrote the initial draft of the paper	Wrote the paper	Writing - Original Draft	YES
5461119	28364566	KC	PLoS52	planned and designed the study|designed the conceptual framework and undertook the literature review to guide instrument design|wrote the survey instrument|analysed the data|wrote the initial draft of the paper|finalized the paper	finalized the paper	Wrote the paper	Writing - Review & Editing	YES
5461119	28364566	KM	PLoS52	led the data set merging and cleaning process|analysed the data	led the data set merging and cleaning process	Analyzed the data	Data curation	YES
5461119	28364566	KM	PLoS52	led the data set merging and cleaning process|analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
5461119	28364566	MM	PLoS52	led the study implementation in their respective countries, including choice of sampling strategy, local adaptations to the questionnaire, and organisation and quality control of data collection	led the study implementation in their respective countries, including choice of sampling strategy, local adaptations to the questionnaire, and organisation and quality control of data collection	Performed the experiments	Investigation|Validation	YES
5461119	28364566	NA	PLoS52	led the study implementation in their respective countries, including choice of sampling strategy, local adaptations to the questionnaire, and organisation and quality control of data collection|coordinated data entry in their countries	led the study implementation in their respective countries, including choice of sampling strategy, local adaptations to the questionnaire, and organisation and quality control of data collection	Performed the experiments	Investigation|Validation	YES
5461119	28364566	NA	PLoS52	led the study implementation in their respective countries, including choice of sampling strategy, local adaptations to the questionnaire, and organisation and quality control of data collection|coordinated data entry in their countries	coordinated data entry in their countries	Analyzed the data	Data curation|Project administration	YES
5461119	28364566	SO	PLoS52	led the study implementation in their respective countries, including choice of sampling strategy, local adaptations to the questionnaire, and organisation and quality control of data collection	led the study implementation in their respective countries, including choice of sampling strategy, local adaptations to the questionnaire, and organisation and quality control of data collection	Performed the experiments	Investigation|Validation	YES
5461119	28364566	VH	PLoS52	led the study implementation in their respective countries, including choice of sampling strategy, local adaptations to the questionnaire, and organisation and quality control of data collection	led the study implementation in their respective countries, including choice of sampling strategy, local adaptations to the questionnaire, and organisation and quality control of data collection	Performed the experiments	Investigation|Validation	YES
535811	15546486	ESTs	2	annotated the est database, performed much of the analyses, interpreted the results, and drafted the manuscript	annotated the est database, performed much of the analyses, interpreted the results, and drafted the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Data curation|Formal analysis|Investigation|Software|Writing - Original Draft	YES
535811	15546486	JZ	2	coded the ht-go-gat software and created the mysql database	coded the ht-go-gat software and created the mysql database	Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Software	YES
535811	15546486	PRP	2	participated in the design of the database and sequence analysis, and participated in the annotation of the individual est sequences	participated in the design of the database and sequence analysis, and participated in the annotation of the individual est sequences	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Formal analysis|Investigation|Software	YES
535811	15546486	SAM	2	participated in the design of the bioinformatics and design of the sequence analysis	participated in the design of the bioinformatics and design of the sequence analysis	Conceived and designed the experiments|Performed the experiments	Formal analysis|Investigation	YES
535811	15546486	SED	2	designed the bioinformatics software and database, performed the sequence alignments, performed the orf analysis, and generated the bryobase website	designed the bioinformatics software and database, performed the sequence alignments, performed the orf analysis, and generated the bryobase website	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Software	YES
6149195	30254746	Jerusha Jeyakumar	7	Data analysis, literature review, writing. Angus	Data analysis, literature review, writing. Angus	Analyzed the data|Wrote the paper	Formal analysis	YES
6149195	30254746	Jeyakumar R. Apollos	7	Concept, design, data collection, writing	Concept, design, data collection, writing	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation	YES
6149195	30254746	K Fadyen	7	Statistical analysis, writing	Statistical analysis, writing	Analyzed the data|Wrote the paper	Formal analysis	YES
6149195	30254746	Manju Nadh Prasanth	7	Design, data collection, data verification	Design, data collection, data verification	Conceived and designed the experiments|Performed the experiments	Investigation|Validation	YES
6149195	30254746	Sharukh Sami	7	Design, data collection, data verification	Design, data collection, data verification	Conceived and designed the experiments|Performed the experiments	Investigation|Validation	YES
4406734	25902065	BJFS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406734	25902065	BJFS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406734	25902065	BJFS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406734	25902065	BJFS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406734	25902065	FB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406734	25902065	FB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406734	25902065	FB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5581828	28900440	HC	2	designed the experiment|contributed to the data analysis and wrote the manuscript	designed the experiment	Conceived and designed the experiments	Methodology	YES
5581828	28900440	HC	2	designed the experiment|contributed to the data analysis and wrote the manuscript	contributed to the data analysis and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5581828	28900440	HL	2	provided suggestions on the experiment design and discussion sections	provided suggestions on the experiment design and discussion sections	Conceived and designed the experiments	Methodology	YES
5581828	28900440	HW	2	designed the experiment|performed the experiment|contributed to the data analysis and wrote the manuscript	designed the experiment	Conceived and designed the experiments	Methodology	YES
5581828	28900440	HW	2	designed the experiment|performed the experiment|contributed to the data analysis and wrote the manuscript	performed the experiment	Performed the experiments	Investigation	YES
5581828	28900440	HW	2	designed the experiment|performed the experiment|contributed to the data analysis and wrote the manuscript	contributed to the data analysis and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5581828	28900440	JL	2	performed the experiment	performed the experiment	Performed the experiments	Investigation	YES
5581828	28900440	JY	2	performed the experiment	performed the experiment	Performed the experiments	Investigation	YES
5581828	28900440	MH	2	performed the experiment	performed the experiment	Performed the experiments	Investigation	YES
5581828	28900440	SH	2	performed the experiment	performed the experiment	Performed the experiments	Investigation	YES
5581828	28900440	YH	2	provided suggestions on the experiment design and discussion sections	provided suggestions on the experiment design and discussion sections	Conceived and designed the experiments	Methodology	YES
5332322	28251575	CMR	2	improved the study design, implemented relevant parts of the algorithm, and contributed to data analysis	improved the study design, implemented relevant parts of the algorithm, and contributed to data analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Methodology|Software	YES
5332322	28251575	MK	2	improved both the study design and the proposed algorithm and helped to interpret the results	improved both the study design and the proposed algorithm and helped to interpret the results	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Methodology|Software	YES
5332322	28251575	MTF	2	collected the patient data and evaluated and analyzed the corresponding results	collected the patient data and evaluated and analyzed the corresponding results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5332322	28251575	TH	2	developed the study design, implemented major parts of the proposed algorithm, performed the phantom measurements, reconstructed the data, analyzed the results, and drafted the manuscript	developed the study design, implemented major parts of the proposed algorithm, performed the phantom measurements, reconstructed the data, analyzed the results, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Software|Writing - Original Draft	YES
5332322	28251575	YB	2	helped to interpret and discuss the results	helped to interpret and discuss the results	Analyzed the data	Formal analysis	YES
2613146	19000306	All authors	2	contributed equally to the manuscript	contributed equally to the manuscript	-	-	NO
6153116	30258625	Chairat Supsamutchai	2	who performed the study design	who performed the study design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6153116	30258625	Chumpon Wilasrusmee	2	who performed the study design	who performed the study design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6153116	30258625	Jakrapan Jirasiritham	2	were contributors	were contributors	-	-	NO
6153116	30258625	Pattawia Choikrua	2	who performed data collection and data analysis	who performed data collection and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6153116	30258625	Pitichote Hiranyatheb	2	were contributors	were contributors	-	-	NO
6153116	30258625	Teerawut Rakchob	2	who performed data collection and data analysis	who performed data collection and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5359807	28327106	IM	2	conceived the project|coded the tool|wrote the manuscript	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5359807	28327106	IM	2	conceived the project|coded the tool|wrote the manuscript	coded the tool	-	-	NO
5359807	28327106	IM	2	conceived the project|coded the tool|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5359807	28327106	MAP	2	conceived the project|wrote the manuscript	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5359807	28327106	MAP	2	conceived the project|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4406735	25901358	CJL	PLoS5	Critically reviewed manuscript and provided significant intellectual feedback	Critically reviewed manuscript and provided significant intellectual feedback	Wrote the paper	Writing - Review & Editing	YES
4406735	25901358	EGR	PLoS5	Conceived and designed the experiments|Performed the experiments|Data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406735	25901358	EGR	PLoS5	Conceived and designed the experiments|Performed the experiments|Data	Performed the experiments	Performed the experiments	Investigation	YES
4406735	25901358	EGR	PLoS5	Conceived and designed the experiments|Performed the experiments|Data	Data	-	-	NO
4406735	25901358	ERG	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406735	25901358	JPWP	PLoS5	Critically reviewed manuscript and provided significant intellectual feedback	Critically reviewed manuscript and provided significant intellectual feedback	Wrote the paper	Writing - Review & Editing	YES
4406735	25901358	MNC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406735	25901358	MNC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406735	25901358	MNC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406735	25901358	RRP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Data|Critically reviewed manuscript and provided significant intellectual feedback	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406735	25901358	RRP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Data|Critically reviewed manuscript and provided significant intellectual feedback	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406735	25901358	RRP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Data|Critically reviewed manuscript and provided significant intellectual feedback	Data	-	-	NO
4406735	25901358	RRP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Data|Critically reviewed manuscript and provided significant intellectual feedback	Critically reviewed manuscript and provided significant intellectual feedback	Wrote the paper	Writing - Review & Editing	YES
4406735	25901358	SNB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Data|Critically reviewed manuscript and provided significant intellectual feedback	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406735	25901358	SNB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Data|Critically reviewed manuscript and provided significant intellectual feedback	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406735	25901358	SNB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Data|Critically reviewed manuscript and provided significant intellectual feedback	Data	-	-	NO
4406735	25901358	SNB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Data|Critically reviewed manuscript and provided significant intellectual feedback	Critically reviewed manuscript and provided significant intellectual feedback	Wrote the paper	Writing - Review & Editing	YES
4406735	25901358	XS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Critically reviewed manuscript and provided significant intellectual feedback	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406735	25901358	XS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Critically reviewed manuscript and provided significant intellectual feedback	Analyzed the data	Analyzed the data	Formal analysis	YES
4406735	25901358	XS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Critically reviewed manuscript and provided significant intellectual feedback	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406735	25901358	XS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Critically reviewed manuscript and provided significant intellectual feedback	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406735	25901358	XS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Critically reviewed manuscript and provided significant intellectual feedback	Critically reviewed manuscript and provided significant intellectual feedback	Wrote the paper	Writing - Review & Editing	YES
5337231	28260215	CB	2	participated in the data collection and image reconstruction work for the hrrt system	participated in the data collection and image reconstruction work for the hrrt system	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
5337231	28260215	JS	2	helped design the phantom study	helped design the phantom study	Conceived and designed the experiments	Methodology	YES
5337231	28260215	JZ	2	participated in the data collection and image reconstruction work for the verios system	participated in the data collection and image reconstruction work for the verios system	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
5337231	28260215	KB	2	participated in the data collection and image reconstruction work for the verios system	participated in the data collection and image reconstruction work for the verios system	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
5337231	28260215	MK	2	provided facilities and resources for the data collected on the verios system	provided facilities and resources for the data collected on the verios system	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5337231	28260215	PC	2	instigated and authorized funding for the study	instigated and authorized funding for the study	-	Funding acquisition	YES
5337231	28260215	RM	2	participated in the data collection and image reconstruction work for the mct system	participated in the data collection and image reconstruction work for the mct system	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
5337231	28260215	SA	2	headed the study, oversaw the phantom data acquisition on all scanners, designed the human observer study, wrote the analysis software, generated all plots and figures, and wrote the main draft of the manuscript and supplemental materials section	headed the study, oversaw the phantom data acquisition on all scanners, designed the human observer study, wrote the analysis software, generated all plots and figures, and wrote the main draft of the manuscript and supplemental materials section	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Software|Supervision|Visualization|Writing - Original Draft	YES
5337231	28260215	SC	2	participated in the data collection and image reconstruction work for the hrrt system	participated in the data collection and image reconstruction work for the hrrt system	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
2613380	19061520	BM	2	read the first version and made editorial suggestions	read the first version and made editorial suggestions	-	-	NO
2613380	19061520	M. They	2	have both read and approved the final version of the manuscript	have both read and approved the final version of the manuscript	-	-	NO
2613380	19061520	SR	2	wrote a first rough draft of the manuscript	wrote a first rough draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
6153120	30258626	AA	1	Study design|Statistical analysis	Study design	Conceived and designed the experiments	Methodology	YES
6153120	30258626	AA	1	Study design|Statistical analysis	Statistical analysis	Analyzed the data	Formal analysis	YES
6153120	30258626	All	1	Critical review and approval of manuscript	Critical review and approval of manuscript	Wrote the paper	Writing - Review & Editing	YES
6153120	30258626	BA	1	Study design|Statistical analysis|Writing first draft of manuscript	Study design	Conceived and designed the experiments	Methodology	YES
6153120	30258626	BA	1	Study design|Statistical analysis|Writing first draft of manuscript	Statistical analysis	Analyzed the data	Formal analysis	YES
6153120	30258626	BA	1	Study design|Statistical analysis|Writing first draft of manuscript	Writing first draft of manuscript	Wrote the paper	Writing - Original Draft	YES
6153120	30258626	DA	1	Study design|Data collection	Study design	Conceived and designed the experiments	Methodology	YES
6153120	30258626	DA	1	Study design|Data collection	Data collection	Performed the experiments	Investigation	YES
6153120	30258626	NA	1	Study design|Data collection|Writing first draft of manuscript	Study design	Conceived and designed the experiments	Methodology	YES
6153120	30258626	NA	1	Study design|Data collection|Writing first draft of manuscript	Data collection	Performed the experiments	Investigation	YES
6153120	30258626	NA	1	Study design|Data collection|Writing first draft of manuscript	Writing first draft of manuscript	Wrote the paper	Writing - Original Draft	YES
6153120	30258626	RA	1	Study design|Study design|Data collection|Statistical analysis|Writing first draft of manuscript	Study design	Conceived and designed the experiments	Methodology	YES
6153120	30258626	RA	1	Study design|Study design|Data collection|Statistical analysis|Writing first draft of manuscript	Study design	Conceived and designed the experiments	Methodology	YES
6153120	30258626	RA	1	Study design|Study design|Data collection|Statistical analysis|Writing first draft of manuscript	Data collection	Performed the experiments	Investigation	YES
6153120	30258626	RA	1	Study design|Study design|Data collection|Statistical analysis|Writing first draft of manuscript	Statistical analysis	Analyzed the data	Formal analysis	YES
6153120	30258626	RA	1	Study design|Study design|Data collection|Statistical analysis|Writing first draft of manuscript	Writing first draft of manuscript	Wrote the paper	Writing - Original Draft	YES
6153120	30258626	RWA	1	Data collection	Data collection	Performed the experiments	Investigation	YES
6153120	30258626	YA	1	Study design|Statistical analysis|Writing first draft of manuscript	Study design	Conceived and designed the experiments	Methodology	YES
6153120	30258626	YA	1	Study design|Statistical analysis|Writing first draft of manuscript	Statistical analysis	Analyzed the data	Formal analysis	YES
6153120	30258626	YA	1	Study design|Statistical analysis|Writing first draft of manuscript	Writing first draft of manuscript	Wrote the paper	Writing - Original Draft	YES
5581829	28900435	GM	2	designed the research, supervised data collection, developed the methodology, performed the analysis and wrote the manuscript	designed the research, supervised data collection, developed the methodology, performed the analysis and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Supervision|Writing - Original Draft	YES
5581829	28900435	M-AM	2	designed the research, supervised data collection, developed the methodology, performed the analysis and wrote the manuscript	designed the research, supervised data collection, developed the methodology, performed the analysis and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Supervision|Writing - Original Draft	YES
5581829	28900435	MC	2	supported the development of the method as well as data analysis and interpretation|also reviewed the manuscript	supported the development of the method as well as data analysis and interpretation	Performed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5581829	28900435	MC	2	supported the development of the method as well as data analysis and interpretation|also reviewed the manuscript	also reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
4512830	26240829	Antonio Colaprico	2	contributed equally to this work	contributed equally to this work	-	-	NO
4512830	26240829	Claudia Cava	2	contributed equally to this work	contributed equally to this work	-	-	NO
5359896	28320314	HS	2	designed the study and supervised sps	designed the study and supervised sps	Conceived and designed the experiments	Methodology|Supervision	YES
5359896	28320314	IWD	2	designed the study and supervised sps|finalized the manuscript	designed the study and supervised sps	Conceived and designed the experiments	Methodology|Supervision	YES
5359896	28320314	IWD	2	designed the study and supervised sps|finalized the manuscript	finalized the manuscript	Wrote the paper	Writing - Review & Editing	YES
5359896	28320314	JT	2	performed bioinformatical and statistical analyses|prepared the figures	performed bioinformatical and statistical analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5359896	28320314	JT	2	performed bioinformatical and statistical analyses|prepared the figures	prepared the figures	-	Visualization	YES
5359896	28320314	MJ	2	prepared sequencing libraries and processed the raw sequences	prepared sequencing libraries and processed the raw sequences	Performed the experiments	Investigation	YES
5359896	28320314	MR	2	provided scanning electron micrographs	provided scanning electron micrographs	-	-	NO
5359896	28320314	SB	2	prepared sequencing libraries and processed the raw sequences	prepared sequencing libraries and processed the raw sequences	Performed the experiments	Investigation	YES
5359896	28320314	SPS	2	conducted the experiments, analysed the data, and wrote the manuscript draft|prepared the figures	conducted the experiments, analysed the data, and wrote the manuscript draft	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5359896	28320314	SPS	2	conducted the experiments, analysed the data, and wrote the manuscript draft|prepared the figures	prepared the figures	-	Visualization	YES
5359896	28320314	ZD	2	performed bioinformatical and statistical analyses|prepared the figures	performed bioinformatical and statistical analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5359896	28320314	ZD	2	performed bioinformatical and statistical analyses|prepared the figures	prepared the figures	-	Visualization	YES
4406736	25902055	AW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406736	25902055	AW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406736	25902055	AW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406736	25902055	AW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406736	25902055	AW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406736	25902055	FM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406736	25902055	FM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406736	25902055	FM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406736	25902055	FM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406736	25902055	FM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406736	25902055	YB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406736	25902055	YB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406736	25902055	YB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406736	25902055	YB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406736	25902055	YB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5346099	28283990	EC	2	drafted the manuscript, made the educational figures and collected the references	drafted the manuscript, made the educational figures and collected the references	Performed the experiments|Wrote the paper	Investigation|Visualization|Writing - Original Draft	YES
5346099	28283990	NB	2	coordinated the drafting, collaborated to the organization of the structure of the manuscript and revised it	coordinated the drafting, collaborated to the organization of the structure of the manuscript and revised it	Wrote the paper	Project administration|Writing - Original Draft|Writing - Review & Editing	YES
6153262	30258624	Beenish Syed	2	has made contribution to acquisition and interpretation of data	has made contribution to acquisition and interpretation of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
6153262	30258624	Hafiz Abdul Basit	2	has made contributions to conception and design, interpretation of data, drafting the manuscript and revising it critically for important intellectual content	has made contributions to conception and design, interpretation of data, drafting the manuscript and revising it critically for important intellectual content	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Resources|Writing - Original Draft|Writing - Review & Editing	YES
6153262	30258624	Hareem Rehman	2	has made contribution in data collection and drafting the manuscript	has made contribution in data collection and drafting the manuscript	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Resources|Writing - Original Draft	YES
6153262	30258624	Rabeea Azmat	2	has made contribution to acquisition and interpretation of data and drafting the manuscript	has made contribution to acquisition and interpretation of data and drafting the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft	YES
6153262	30258624	Saleemullah Paracha	2	has made contribution in revising the manuscript	has made contribution in revising the manuscript	Wrote the paper	Writing - Review & Editing	YES
6153262	30258624	Shiyam Sundar Tikmani	2	has made contribution in acquision and interpretation of data and drafting the manuscript	has made contribution in acquision and interpretation of data and drafting the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
6153262	30258624	Shumaila Rafi	2	has made contribution to acquisition and interpretation of data and drafting the manuscript	has made contribution to acquisition and interpretation of data and drafting the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft	YES
6153262	30258624	Tahir Rizwan Khan	2	has made interpretation of data and in revising the manuscript	has made interpretation of data and in revising the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5822812	29576883	AFTV	2	on request	on request	-	-	NO
5822812	29576883	Yuki Imaoka	2	gave the patients additional treatments	gave the patients additional treatments	-	-	NO
5822812	29576883	Yuusuke Sumi	2	gave the patients additional treatments	gave the patients additional treatments	-	-	NO
5581835	28900434	AL	2	performed field work and analyzed data	performed field work and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5581835	28900434	BH	2	designed the study|performed field work and analyzed data	designed the study	Conceived and designed the experiments	Methodology	YES
5581835	28900434	BH	2	designed the study|performed field work and analyzed data	performed field work and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5581835	28900434	IS-D	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5581835	28900434	JK	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5581835	28900434	SR	2	performed field work and analyzed data|wrote the first draft of the manuscript, and all authors contributed to revisions	performed field work and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5581835	28900434	SR	2	performed field work and analyzed data|wrote the first draft of the manuscript, and all authors contributed to revisions	wrote the first draft of the manuscript, and all authors contributed to revisions	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4406737	25902139	HH	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406737	25902139	HH	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406737	25902139	HH	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406737	25902139	KK	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406737	25902139	KK	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406737	25902139	KK	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406737	25902139	KM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406737	25902139	KM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406737	25902139	KM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406737	25902139	MI	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406737	25902139	MI	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406737	25902139	MI	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406737	25902139	SF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406737	25902139	SF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406737	25902139	SF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406737	25902139	SF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406737	25902139	XY	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406737	25902139	XY	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406737	25902139	YL	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406737	25902139	YL	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406737	25902139	YX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406737	25902139	YX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406737	25902139	YX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406737	25902139	YX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5407393	28451906	All authors	2	made equal and substantial contributions to the conception and design of this manuscript, were directly involved in drafting and revising of the manuscript, gave final approval of the version to be published, and agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	made equal and substantial contributions to the conception and design of this manuscript, were directly involved in drafting and revising of the manuscript, gave final approval of the version to be published, and agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
5359931	28320315	EHR	2	conceived the project, designed experiments, and interpreted the findings	conceived the project, designed experiments, and interpreted the findings	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
5359931	28320315	WRR	2	collected grew plant material, extracted rna, performed all analyses, and wrote the manuscript|conceived the project, designed experiments, and interpreted the findings	collected grew plant material, extracted rna, performed all analyses, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5359931	28320315	WRR	2	collected grew plant material, extracted rna, performed all analyses, and wrote the manuscript|conceived the project, designed experiments, and interpreted the findings	conceived the project, designed experiments, and interpreted the findings	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
3966317	24711925	Bruce A. Larson	PLoS52	assisted with interpretation of results|reviewed and edited the paper	assisted with interpretation of results	Analyzed the data	Formal analysis	YES
3966317	24711925	Bruce A. Larson	PLoS52	assisted with interpretation of results|reviewed and edited the paper	reviewed and edited the paper	Wrote the paper	Writing - Review & Editing	YES
3966317	24711925	Callie A. Scott	PLoS52	analyzed the data|assisted with interpretation of results|reviewed and edited the paper	analyzed the data	Analyzed the data	Formal analysis	YES
3966317	24711925	Callie A. Scott	PLoS52	analyzed the data|assisted with interpretation of results|reviewed and edited the paper	assisted with interpretation of results	Analyzed the data	Formal analysis	YES
3966317	24711925	Callie A. Scott	PLoS52	analyzed the data|assisted with interpretation of results|reviewed and edited the paper	reviewed and edited the paper	Wrote the paper	Writing - Review & Editing	YES
3966317	24711925	Carolyn Bolton Moore	PLoS52	assisted with interpretation of results|reviewed and edited the paper	assisted with interpretation of results	Analyzed the data	Formal analysis	YES
3966317	24711925	Carolyn Bolton Moore	PLoS52	assisted with interpretation of results|reviewed and edited the paper	reviewed and edited the paper	Wrote the paper	Writing - Review & Editing	YES
3966317	24711925	Crispin Moyo	PLoS52	assisted with interpretation of results|reviewed and edited the paper	assisted with interpretation of results	Analyzed the data	Formal analysis	YES
3966317	24711925	Crispin Moyo	PLoS52	assisted with interpretation of results|reviewed and edited the paper	reviewed and edited the paper	Wrote the paper	Writing - Review & Editing	YES
3966317	24711925	Deophine Lembela Bwalya	PLoS52	assisted with interpretation of results|reviewed and edited the paper	assisted with interpretation of results	Analyzed the data	Formal analysis	YES
3966317	24711925	Deophine Lembela Bwalya	PLoS52	assisted with interpretation of results|reviewed and edited the paper	reviewed and edited the paper	Wrote the paper	Writing - Review & Editing	YES
3966317	24711925	Gesine Meyer-Rath	PLoS52	assisted with interpretation of results|reviewed and edited the paper	assisted with interpretation of results	Analyzed the data	Formal analysis	YES
3966317	24711925	Gesine Meyer-Rath	PLoS52	assisted with interpretation of results|reviewed and edited the paper	reviewed and edited the paper	Wrote the paper	Writing - Review & Editing	YES
3966317	24711925	Hari S. Iyer	PLoS52	analyzed the data|assisted with interpretation of results|wrote the first draft of the paper|reviewed and edited the paper	analyzed the data	Analyzed the data	Formal analysis	YES
3966317	24711925	Hari S. Iyer	PLoS52	analyzed the data|assisted with interpretation of results|wrote the first draft of the paper|reviewed and edited the paper	assisted with interpretation of results	Analyzed the data	Formal analysis	YES
3966317	24711925	Hari S. Iyer	PLoS52	analyzed the data|assisted with interpretation of results|wrote the first draft of the paper|reviewed and edited the paper	wrote the first draft of the paper	Wrote the paper	Writing - Original Draft	YES
3966317	24711925	Hari S. Iyer	PLoS52	analyzed the data|assisted with interpretation of results|wrote the first draft of the paper|reviewed and edited the paper	reviewed and edited the paper	Wrote the paper	Writing - Review & Editing	YES
3966317	24711925	Sydney Rosen	PLoS52	assisted with interpretation of results|reviewed and edited the paper	assisted with interpretation of results	Analyzed the data	Formal analysis	YES
3966317	24711925	Sydney Rosen	PLoS52	assisted with interpretation of results|reviewed and edited the paper	reviewed and edited the paper	Wrote the paper	Writing - Review & Editing	YES
2642860	19146696	All authors	2	contributed equally and have read and approved the manuscript	contributed equally and have read and approved the manuscript	-	-	NO
6154768	30258627	Claudia Romagnoni	2	performed the data collection	performed the data collection	Performed the experiments	Investigation	YES
6154768	30258627	Manel Tauron Ferrer	2	performed the data collection	performed the data collection	Performed the experiments	Investigation	YES
6154768	30258627	Monica Contino	2	performed the data collection	performed the data collection	Performed the experiments	Investigation	YES
6154768	30258627	Petra Baumann	2	designed the study|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
6154768	30258627	Petra Baumann	2	designed the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6154768	30258627	Viktor Breul	2	was responsible for data analysis	was responsible for data analysis	Analyzed the data	Formal analysis	YES
4406738	25901727	ETS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406738	25901727	ETS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406738	25901727	ETS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406738	25901727	ETS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406738	25901727	ETS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5581838	28900441	CL	2	conceived and designed research|analyzed data|wrote the manuscript	conceived and designed research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5581838	28900441	CL	2	conceived and designed research|analyzed data|wrote the manuscript	analyzed data	Analyzed the data	Formal analysis	YES
5581838	28900441	CL	2	conceived and designed research|analyzed data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5581838	28900441	PC	2	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5581838	28900441	ST	2	conducted experiments|analyzed data|wrote the manuscript	conducted experiments	Performed the experiments	Investigation	YES
5581838	28900441	ST	2	conducted experiments|analyzed data|wrote the manuscript	analyzed data	Analyzed the data	Formal analysis	YES
5581838	28900441	ST	2	conducted experiments|analyzed data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5581838	28900441	VP	2	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5359932	28327095	AN	PLoS52	established ngs methodologies and acquired the rna seq data	established ngs methodologies and acquired the rna seq data	Performed the experiments	Investigation|Methodology	YES
5359932	28327095	FF	PLoS52	performed the bioinformatics analysis	performed the bioinformatics analysis	Performed the experiments	Formal analysis|Investigation	YES
5359932	28327095	RM	PLoS52	performed the bioinformatics analysis|conceived the study and oversaw the project|wrote the paper	performed the bioinformatics analysis	Performed the experiments	Formal analysis|Investigation	YES
5359932	28327095	RM	PLoS52	performed the bioinformatics analysis|conceived the study and oversaw the project|wrote the paper	conceived the study and oversaw the project	Conceived and designed the experiments	Conceptualization|Supervision	YES
5359932	28327095	RM	PLoS52	performed the bioinformatics analysis|conceived the study and oversaw the project|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5359932	28327095	SL	PLoS52	carried out rna isolation, rt qpcr analyses, rna seq library construction and quality control experiments	carried out rna isolation, rt qpcr analyses, rna seq library construction and quality control experiments	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Validation	YES
5359932	28327095	SMB	PLoS52	conceived the study and oversaw the project	conceived the study and oversaw the project	Conceived and designed the experiments	Conceptualization|Supervision	YES
5359932	28327095	SR	PLoS52	prepared and characterized tam samples and performed flow cytometry and elisa analyses|conceived the study and oversaw the project	prepared and characterized tam samples and performed flow cytometry and elisa analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5359932	28327095	SR	PLoS52	prepared and characterized tam samples and performed flow cytometry and elisa analyses|conceived the study and oversaw the project	conceived the study and oversaw the project	Conceived and designed the experiments	Conceptualization|Supervision	YES
5359932	28327095	TA	PLoS52	carried out rna isolation, rt qpcr analyses, rna seq library construction and quality control experiments|conceived the study and oversaw the project	carried out rna isolation, rt qpcr analyses, rna seq library construction and quality control experiments	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Validation	YES
5359932	28327095	TA	PLoS52	carried out rna isolation, rt qpcr analyses, rna seq library construction and quality control experiments|conceived the study and oversaw the project	conceived the study and oversaw the project	Conceived and designed the experiments	Conceptualization|Supervision	YES
5359932	28327095	TS	PLoS52	established ngs methodologies and acquired the rna seq data	established ngs methodologies and acquired the rna seq data	Performed the experiments	Investigation|Methodology	YES
5359932	28327095	UW	PLoS52	provided clinical samples and analyzed clinical data	provided clinical samples and analyzed clinical data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
2644722	19216749	Both authors	2	contributed to the writing and critical revision of the manuscript	contributed to the writing and critical revision of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5413461	28466279	CT	2	reconstruction, image registration and quantification, and manuscript correction|reconstruction, and image registration and quantification	reconstruction, image registration and quantification, and manuscript correction	Performed the experiments|Analyzed the data|Wrote the paper	Investigation|Visualization|Writing - Review & Editing	YES
5413461	28466279	CT	2	reconstruction, image registration and quantification, and manuscript correction|reconstruction, and image registration and quantification	reconstruction, and image registration and quantification	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
5413461	28466279	GP	2	contributed to the animal handling	contributed to the animal handling	Performed the experiments	Investigation	YES
5413461	28466279	JV	2	contributed to the mri sequence development	contributed to the mri sequence development	Performed the experiments	Investigation	YES
5413461	28466279	MRI	2	acquisitions, and manuscript writing|acquisitions, and manuscript correction	acquisitions, and manuscript writing	Wrote the paper	Writing - Original Draft	YES
5413461	28466279	MRI	2	acquisitions, and manuscript writing|acquisitions, and manuscript correction	acquisitions, and manuscript correction	Wrote the paper	Writing - Review & Editing	YES
5413461	28466279	VL	2	contributed to the study design	contributed to the study design	Conceived and designed the experiments	Methodology	YES
4406739	25902191	BB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406739	25902191	BB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406739	25902191	BB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406739	25902191	BB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406739	25902191	BB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406739	25902191	JL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4406739	25902191	MM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406739	25902191	MM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406739	25902191	MM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406739	25902191	MM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406739	25902191	NW	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406739	25902191	NW	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406739	25902191	XQ	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4406739	25902191	XQ	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
6156740	30263116	AFK	2	contributed to performed the operation, data collection, analysis and interpretation, manuscript drafting, revising, and approval for publishing	contributed to performed the operation, data collection, analysis and interpretation, manuscript drafting, revising, and approval for publishing	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft	YES
6156740	30263116	DS	2	contributed to performed the operation, data collection, analysis and interpretation, manuscript drafting, revising, and approval for publishing	contributed to performed the operation, data collection, analysis and interpretation, manuscript drafting, revising, and approval for publishing	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft	YES
6156740	30263116	IO	2	contributed to assist the operation, data collection, analysis and interpretation, manuscript drafting, revising, and approval for publishing	contributed to assist the operation, data collection, analysis and interpretation, manuscript drafting, revising, and approval for publishing	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft	YES
2669094	19226449	Both authors	2	have contributed equally to the article	have contributed equally to the article	-	-	NO
5359956	28320307	AJ	2	were involved in formulating the research question and designing the study	were involved in formulating the research question and designing the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5359956	28320307	DS	2	were involved in formulating the research question and designing the study|performed the bioinformatic analysis regarding the transcriptomics|were involved in the writing	were involved in formulating the research question and designing the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5359956	28320307	DS	2	were involved in formulating the research question and designing the study|performed the bioinformatic analysis regarding the transcriptomics|were involved in the writing	performed the bioinformatic analysis regarding the transcriptomics	Performed the experiments	Formal analysis|Investigation	YES
5359956	28320307	DS	2	were involved in formulating the research question and designing the study|performed the bioinformatic analysis regarding the transcriptomics|were involved in the writing	were involved in the writing	Wrote the paper	-	YES
5359956	28320307	GV	2	were involved in formulating the research question and designing the study	were involved in formulating the research question and designing the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5359956	28320307	JR	2	were involved in formulating the research question and designing the study|were involved in the writing	were involved in formulating the research question and designing the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5359956	28320307	JR	2	were involved in formulating the research question and designing the study|were involved in the writing	were involved in the writing	Wrote the paper	-	YES
5359956	28320307	MS	2	were involved in formulating the research question and designing the study|were involved in the writing	were involved in formulating the research question and designing the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5359956	28320307	MS	2	were involved in formulating the research question and designing the study|were involved in the writing	were involved in the writing	Wrote the paper	-	YES
5359956	28320307	SV	2	was involved in carrying out the laboratory work regarding the microbiota and transcriptomics	was involved in carrying out the laboratory work regarding the microbiota and transcriptomics	Performed the experiments	Investigation	YES
5449363	28560574	CD	1	Data gathering	Data gathering	-	-	NO
5449363	28560574	CL	1	Study design|Study coordination|Data gathering|Data analysis|Manuscript writing	Study design	Conceived and designed the experiments	Methodology	YES
5449363	28560574	CL	1	Study design|Study coordination|Data gathering|Data analysis|Manuscript writing	Study coordination	-	Project administration	YES
5449363	28560574	CL	1	Study design|Study coordination|Data gathering|Data analysis|Manuscript writing	Data gathering	-	-	NO
5449363	28560574	CL	1	Study design|Study coordination|Data gathering|Data analysis|Manuscript writing	Data analysis	Analyzed the data	Formal analysis	YES
5449363	28560574	CL	1	Study design|Study coordination|Data gathering|Data analysis|Manuscript writing	Manuscript writing	Wrote the paper	Writing - Original Draft	YES
5449363	28560574	DB	1	Data gathering	Data gathering	-	-	NO
5449363	28560574	DS	1	Data gathering	Data gathering	-	-	NO
5449363	28560574	EQ	1	Study design|Data gathering|Data analysis|Manuscript writing	Study design	Conceived and designed the experiments	Methodology	YES
5449363	28560574	EQ	1	Study design|Data gathering|Data analysis|Manuscript writing	Data gathering	-	-	NO
5449363	28560574	EQ	1	Study design|Data gathering|Data analysis|Manuscript writing	Data analysis	Analyzed the data	Formal analysis	YES
5449363	28560574	EQ	1	Study design|Data gathering|Data analysis|Manuscript writing	Manuscript writing	Wrote the paper	Writing - Original Draft	YES
5449363	28560574	JC	1	Data gathering	Data gathering	-	-	NO
5449363	28560574	MH	1	Data gathering|Manuscript writing	Data gathering	-	-	NO
5449363	28560574	MH	1	Data gathering|Manuscript writing	Manuscript writing	Wrote the paper	Writing - Original Draft	YES
5449363	28560574	NA	1	Study coordination|Data gathering|Data analysis|Manuscript writing	Study coordination	-	Project administration	YES
5449363	28560574	NA	1	Study coordination|Data gathering|Data analysis|Manuscript writing	Data gathering	-	-	NO
5449363	28560574	NA	1	Study coordination|Data gathering|Data analysis|Manuscript writing	Data analysis	Analyzed the data	Formal analysis	YES
5449363	28560574	NA	1	Study coordination|Data gathering|Data analysis|Manuscript writing	Manuscript writing	Wrote the paper	Writing - Original Draft	YES
5449363	28560574	PR	1	Data gathering|Data analysis	Data gathering	-	-	NO
5449363	28560574	PR	1	Data gathering|Data analysis	Data analysis	Analyzed the data	Formal analysis	YES
5449363	28560574	PYL	1	Study design|Data gathering|Data analysis|Manuscript writing	Study design	Conceived and designed the experiments	Methodology	YES
5449363	28560574	PYL	1	Study design|Data gathering|Data analysis|Manuscript writing	Data gathering	-	-	NO
5449363	28560574	PYL	1	Study design|Data gathering|Data analysis|Manuscript writing	Data analysis	Analyzed the data	Formal analysis	YES
5449363	28560574	PYL	1	Study design|Data gathering|Data analysis|Manuscript writing	Manuscript writing	Wrote the paper	Writing - Original Draft	YES
5449363	28560574	PYS	1	Data gathering	Data gathering	-	-	NO
5449363	28560574	RH	1	Study design|Manuscript writing	Study design	Conceived and designed the experiments	Methodology	YES
5449363	28560574	RH	1	Study design|Manuscript writing	Manuscript writing	Wrote the paper	Writing - Original Draft	YES
5449363	28560574	RL	1	Data gathering	Data gathering	-	-	NO
5581881	28900437	ALGC	2	conceived and wrote the manuscript	conceived and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5581881	28900437	TM	2	drafted and edited the manuscript	drafted and edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4406740	25902138	NKV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406740	25902138	NKV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406740	25902138	NKV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406740	25902138	NKV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406740	25902138	RJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406740	25902138	RJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406740	25902138	RJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406740	25902138	RJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406740	25902138	RJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3676905	23766726	A. Boneberger	2	revised the paper critically for intellectual content	revised the paper critically for intellectual content	Wrote the paper	Writing - Review & Editing	YES
3676905	23766726	K. Radon	2	planned, designed, and organised the study	planned, designed, and organised the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3676905	23766726	L. Kausel	2	planned, designed, and organised the study|participated in the acquisition and statistical analyses of the data	planned, designed, and organised the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3676905	23766726	L. Kausel	2	planned, designed, and organised the study|participated in the acquisition and statistical analyses of the data	participated in the acquisition and statistical analyses of the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3676905	23766726	M. Calvo	2	planned, designed, and organised the study	planned, designed, and organised the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
2674470	19368737	TJP	2	is responsible for the entire manuscript	is responsible for the entire manuscript	-	-	NO
5360061	28320322	ASJ	2	performed research and collected data	performed research and collected data	Performed the experiments	Investigation	YES
5360061	28320322	DGH	2	performed research and collected data	performed research and collected data	Performed the experiments	Investigation	YES
5360061	28320322	IAB	2	performed research and collected data	performed research and collected data	Performed the experiments	Investigation	YES
5360061	28320322	JV	2	performed research, analyzed and interpreted data and wrote the paper	performed research, analyzed and interpreted data and wrote the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5360061	28320322	LP	2	performed research and interpreted data	performed research and interpreted data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5360061	28320322	MCH	2	performed research, interpreted and wrote the paper	performed research, interpreted and wrote the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5360061	28320322	ML	2	performed research, analyzed and interpreted data and wrote the paper	performed research, analyzed and interpreted data and wrote the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5360061	28320322	PV	2	performed research and collected data	performed research and collected data	Performed the experiments	Investigation	YES
5360061	28320322	RCHV	2	performed research, interpreted and wrote the paper	performed research, interpreted and wrote the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5360061	28320322	SAK	2	performed research and collected data	performed research and collected data	Performed the experiments	Investigation	YES
5360061	28320322	TMCMK	2	performed research and collected data	performed research and collected data	Performed the experiments	Investigation	YES
4406741	25902054	BP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406741	25902054	BP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406741	25902054	BP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406741	25902054	DB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4406741	25902054	FL	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406741	25902054	FL	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406741	25902054	FM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406741	25902054	FM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406741	25902054	FM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406741	25902054	GR	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406741	25902054	GR	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406741	25902054	JR	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406741	25902054	JR	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406741	25902054	KF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406741	25902054	KF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406741	25902054	KF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406741	25902054	KF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406741	25902054	ME	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406741	25902054	ME	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406741	25902054	MF	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406741	25902054	MF	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406741	25902054	MH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4406741	25902054	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406741	25902054	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406741	25902054	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406741	25902054	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406741	25902054	MM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406741	25902054	MM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406741	25902054	MM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406741	25902054	MM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406741	25902054	WT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406741	25902054	WT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406741	25902054	WT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406741	25902054	WT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6156742	30263113	Christophe Nouediou	2	developed the study concept, design and data collection	developed the study concept, design and data collection	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
6156742	30263113	Elroy Patrick Weledji	2	carried out the study design, data analysis, interpretation, writing of paper and literature search	carried out the study design, data analysis, interpretation, writing of paper and literature search	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
6156742	30263113	Neville Telelen Alemnju	2	carried out the study design, data collection, data analysis and literature search	carried out the study design, data collection, data analysis and literature search	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
2690600	19442284	ChL	2	discussed initially the project, read and corrected various versions of the manuscript and helped develop arguments	discussed initially the project, read and corrected various versions of the manuscript and helped develop arguments	Wrote the paper	Writing - Review & Editing	YES
2690600	19442284	DP	2	initiated the project and wrote the manuscript	initiated the project and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
2690600	19442284	MW	2	discussed initially the project, read and corrected various versions of the manuscript and helped develop arguments	discussed initially the project, read and corrected various versions of the manuscript and helped develop arguments	Wrote the paper	Writing - Review & Editing	YES
5581882	28900432	All authors	2	participated in outlining the manuscript contents, searching the literature, writing and editing the text	participated in outlining the manuscript contents, searching the literature, writing and editing the text	Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5457380	28577291	AF	2	participated in the critical revision of the manuscript|operated the device	participated in the critical revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5457380	28577291	AF	2	participated in the critical revision of the manuscript|operated the device	operated the device	Performed the experiments	Investigation	YES
5457380	28577291	JMB	2	participated in the critical revision of the manuscript	participated in the critical revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5457380	28577291	JPM	2	designed the device|participated in the critical revision of the manuscript	designed the device	Conceived and designed the experiments	-	YES
5457380	28577291	JPM	2	designed the device|participated in the critical revision of the manuscript	participated in the critical revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5457380	28577291	LAH	2	designed the device|participated in the critical revision of the manuscript	designed the device	Conceived and designed the experiments	-	YES
5457380	28577291	LAH	2	designed the device|participated in the critical revision of the manuscript	participated in the critical revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5457380	28577291	LC	2	participated in the critical revision of the manuscript|did the measurements	participated in the critical revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5457380	28577291	LC	2	participated in the critical revision of the manuscript|did the measurements	did the measurements	Performed the experiments	Investigation	YES
5457380	28577291	PD	2	designed the device|participated in the critical revision of the manuscript|approved the final content	designed the device	Conceived and designed the experiments	-	YES
5457380	28577291	PD	2	designed the device|participated in the critical revision of the manuscript|approved the final content	participated in the critical revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5457380	28577291	PD	2	designed the device|participated in the critical revision of the manuscript|approved the final content	approved the final content	-	-	NO
5457380	28577291	RE	2	designed the device|participated in the critical revision of the manuscript|did the measurements|drafted the manuscript and carried out the data analysis and interpretation|operated the device	designed the device	Conceived and designed the experiments	-	YES
5457380	28577291	RE	2	designed the device|participated in the critical revision of the manuscript|did the measurements|drafted the manuscript and carried out the data analysis and interpretation|operated the device	participated in the critical revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5457380	28577291	RE	2	designed the device|participated in the critical revision of the manuscript|did the measurements|drafted the manuscript and carried out the data analysis and interpretation|operated the device	did the measurements	Performed the experiments	Investigation	YES
5457380	28577291	RE	2	designed the device|participated in the critical revision of the manuscript|did the measurements|drafted the manuscript and carried out the data analysis and interpretation|operated the device	drafted the manuscript and carried out the data analysis and interpretation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5457380	28577291	RE	2	designed the device|participated in the critical revision of the manuscript|did the measurements|drafted the manuscript and carried out the data analysis and interpretation|operated the device	operated the device	Performed the experiments	Investigation	YES
5765212	29399220	Jaydeep Moro	2	assisted data collection by referring his scheduled surgical patients to the lab	assisted data collection by referring his scheduled surgical patients to the lab	Performed the experiments	Investigation	YES
5765212	29399220	Joy MacDermid	2	provided expertise facility network with lab support for data collection, refined objectives and design of the study and edited the manuscript	provided expertise facility network with lab support for data collection, refined objectives and design of the study and edited the manuscript	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Methodology|Resources|Writing - Review & Editing	YES
5765212	29399220	R Gross	2	provided their content expertise and edited the manuscript	provided their content expertise and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5765212	29399220	Zakir Uddin	2	conceptualized the research question, study design, data collection, data analyses and prepared the draft of the manuscript	conceptualized the research question, study design, data collection, data analyses and prepared the draft of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
6160393	30271592	AB	2	have contributed in drafting and editing the manuscript	have contributed in drafting and editing the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6160393	30271592	AP	2	are the senior author of the study	are the senior author of the study	-	-	NO
6160393	30271592	JH	2	has drafted the manuscript	has drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
6160393	30271592	MS	2	edited part of the manuscript and had lead role in the esmsc course	edited part of the manuscript and had lead role in the esmsc course	Wrote the paper	Writing - Review & Editing	YES
6160393	30271592	PT	2	have contributed in drafting and editing the manuscript	have contributed in drafting and editing the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6160393	30271592	PW	2	are the senior author of the study	are the senior author of the study	-	-	NO
6160393	30271592	TP	2	have contributed in drafting and editing the manuscript	have contributed in drafting and editing the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4406742	25901360	FL	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4406742	25901360	JG	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406742	25901360	JG	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406742	25901360	QC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406742	25901360	YL	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406742	25901360	YL	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4406742	25901360	ZD	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406742	25901360	ZZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5361696	28330463	All authors	2	read, commented, and approved the final manuscript	read, commented, and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5361696	28330463	BX	2	participated in data analysis and experiments coordination	participated in data analysis and experiments coordination	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Project administration	YES
5361696	28330463	MY	2	performed the most of experiments and data analysis	performed the most of experiments and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5361696	28330463	MZ	2	collected the samples	collected the samples	Performed the experiments	Investigation	YES
5361696	28330463	SW	2	performed qrt pcr	performed qrt pcr	Performed the experiments	Investigation	YES
5361696	28330463	WY	2	performed qrt pcr	performed qrt pcr	Performed the experiments	Investigation	YES
5361696	28330463	XL	2	participated in data analysis and experiments coordination	participated in data analysis and experiments coordination	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Project administration	YES
5361696	28330463	YX	2	conceived study and wrote manuscript	conceived study and wrote manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5361696	28330463	ZF	2	participated in data analysis and experiments coordination	participated in data analysis and experiments coordination	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Project administration	YES
2714001	19555473	Both authors	2	contributed equally to the text	contributed equally to the text	Wrote the paper	Writing - Original Draft	YES
4406743	25902066	AMB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406743	25902066	AMB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406743	25902066	AMB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406743	25902066	AMB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406743	25902066	KLT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406743	25902066	KLT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406743	25902066	KLT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406743	25902066	KLT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406743	25902066	KLT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406743	25902066	MW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406743	25902066	MW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406743	25902066	MW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406743	25902066	MW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2714322	19589140	ESS	2	developed this work collaboratively	developed this work collaboratively	-	-	NO
2714322	19589140	SEM	2	developed this work collaboratively	developed this work collaboratively	-	-	NO
5581910	28900436	All authors	2	read and approved the final version of the manuscript	read and approved the final version of the manuscript	-	-	NO
5581910	28900436	EW	2	made relevant contributions to the data analysis process|critically revised the manuscript	made relevant contributions to the data analysis process	Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Formal analysis|Resources	YES
5581910	28900436	EW	2	made relevant contributions to the data analysis process|critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5581910	28900436	JP	2	made relevant contributions to the data analysis process|critically revised the manuscript	made relevant contributions to the data analysis process	Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Formal analysis|Resources	YES
5581910	28900436	JP	2	made relevant contributions to the data analysis process|critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5581910	28900436	LL	2	designed the study and set up the analysis|processed and analyzed the data	designed the study and set up the analysis	Conceived and designed the experiments|Performed the experiments	Methodology	YES
5581910	28900436	LL	2	designed the study and set up the analysis|processed and analyzed the data	processed and analyzed the data	Analyzed the data	Data curation|Formal analysis	YES
5581910	28900436	MK	2	designed the study and set up the analysis|critically revised the manuscript	designed the study and set up the analysis	Conceived and designed the experiments|Performed the experiments	Methodology	YES
5581910	28900436	MK	2	designed the study and set up the analysis|critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5581910	28900436	PE	2	made relevant contributions to the data analysis process|critically revised the manuscript	made relevant contributions to the data analysis process	Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Formal analysis|Resources	YES
5581910	28900436	PE	2	made relevant contributions to the data analysis process|critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
6161416	30275949	A S. Agrawal	7	study design, analysis, writing	study design, analysis, writing	Conceived and designed the experiments|Wrote the paper	Methodology	YES
6161416	30275949	FRCS	7	study design, data collection, analysis, writing. Rasheed S - data collection. Davids J - data collection. Aguilo R - data collection	study design, data collection, analysis, writing. Rasheed S - data collection. Davids J - data collection. Aguilo R - data collection	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology	YES
5500602	28685477	ACP	2	contributed to the study design, data analysis, and participated in the critical revision of the manuscript	contributed to the study design, data analysis, and participated in the critical revision of the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Review & Editing	YES
5500602	28685477	JEL	2	contributed to the phantom development, study design, data analysis, and participated in the critical revision of the manuscript	contributed to the phantom development, study design, data analysis, and participated in the critical revision of the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5500602	28685477	MSA	2	drafted the manuscript and contributed to the phantom development, study design, data collection and data analysis and interpretation	drafted the manuscript and contributed to the phantom development, study design, data collection and data analysis and interpretation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
5500602	28685477	PSR	2	contributed to the design of the internal jig and the simulated thyroid gland	contributed to the design of the internal jig and the simulated thyroid gland	Conceived and designed the experiments	Formal analysis	YES
5500602	28685477	SLB	2	contributed to the phantom development, study design, data analysis, and participated in the critical revision of the manuscript	contributed to the phantom development, study design, data analysis, and participated in the critical revision of the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
4406745	25901941	JW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406745	25901941	JW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406745	25901941	JW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406745	25901941	JW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406745	25901941	JW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406745	25901941	LW	PLoS5	Collected samples	Collected samples	Performed the experiments	Investigation	YES
4406745	25901941	QL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406745	25901941	QL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406745	25901941	QL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406745	25901941	QL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406745	25901941	SC	PLoS5	Collected samples	Collected samples	Performed the experiments	Investigation	YES
5361837	28327084	AS	1	Conception and realization of statistical and bioinformatics analyses	Conception and realization of statistical and bioinformatics analyses	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
5361837	28327084	AV	1	Conducting molecular studies	Conducting molecular studies	Performed the experiments	Investigation	YES
5361837	28327084	DC	1	Conception and realization of statistical and bioinformatics analyses	Conception and realization of statistical and bioinformatics analyses	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
5361837	28327084	FG	1	Conception, design and realization of the study|Analysis and interpretation of data|Coordination of the study, drafting of the manuscript	Conception, design and realization of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5361837	28327084	FG	1	Conception, design and realization of the study|Analysis and interpretation of data|Coordination of the study, drafting of the manuscript	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
5361837	28327084	FG	1	Conception, design and realization of the study|Analysis and interpretation of data|Coordination of the study, drafting of the manuscript	Coordination of the study, drafting of the manuscript	Wrote the paper	Project administration|Writing - Original Draft	YES
5361837	28327084	HG	1	Selection of the divergent lines	Selection of the divergent lines	-	-	NO
5361837	28327084	IL	1	Conception, design and realization of the study|Analysis and interpretation of data	Conception, design and realization of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5361837	28327084	IL	1	Conception, design and realization of the study|Analysis and interpretation of data	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
5361837	28327084	MHB	1	Conception and realization of statistical and bioinformatics analyses	Conception and realization of statistical and bioinformatics analyses	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
5361837	28327084	SL	1	Conception, design and realization of the study|Analysis and interpretation of data	Conception, design and realization of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5361837	28327084	SL	1	Conception, design and realization of the study|Analysis and interpretation of data	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
5581911	28900439	FG	1	Writing of the manuscript	Writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5581911	28900439	HS	1	Writing of the manuscript	Writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5581911	28900439	YV	1	Original idea|Writing of the manuscript	Original idea	Conceived and designed the experiments	Conceptualization	YES
5581911	28900439	YV	1	Original idea|Writing of the manuscript	Writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
6170204	30294429	BP	2	performed animal vaccination and flow-cytometry	performed animal vaccination and flow-cytometry	Performed the experiments	Investigation	YES
6170204	30294429	FZH	2	drafted and revised the manuscript	drafted and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6170204	30294429	IM	2	wrote the manuscript and participated in the study design	wrote the manuscript and participated in the study design	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
6170204	30294429	MR	2	drafted and revised the manuscript	drafted and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6051114	30057821	All coauthors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6051114	30057821	Gabriela Naf	2	contributed equally to this publication	contributed equally to this publication	-	-	NO
6051114	30057821	Urs E. Gasser	2	contributed equally to this publication	contributed equally to this publication	-	-	NO
4406746	25902058	DLS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406746	25902058	DLS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406746	25902058	DLS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406746	25902058	JME	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Organizing the field expedition|Studies on the herbarium specimens	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406746	25902058	JME	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Organizing the field expedition|Studies on the herbarium specimens	Analyzed the data	Analyzed the data	Formal analysis	YES
4406746	25902058	JME	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Organizing the field expedition|Studies on the herbarium specimens	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406746	25902058	JME	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Organizing the field expedition|Studies on the herbarium specimens	Organizing the field expedition	-	-	NO
4406746	25902058	JME	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Organizing the field expedition|Studies on the herbarium specimens	Studies on the herbarium specimens	Performed the experiments	Investigation	YES
4406746	25902058	KJ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Obtained permission for conducting the field study|Organizing the field expedition	Performed the experiments	Performed the experiments	Investigation	YES
4406746	25902058	KJ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Obtained permission for conducting the field study|Organizing the field expedition	Analyzed the data	Analyzed the data	Formal analysis	YES
4406746	25902058	KJ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Obtained permission for conducting the field study|Organizing the field expedition	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406746	25902058	KJ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Obtained permission for conducting the field study|Organizing the field expedition	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406746	25902058	KJ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Obtained permission for conducting the field study|Organizing the field expedition	Obtained permission for conducting the field study	Performed the experiments	Investigation	YES
4406746	25902058	KJ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Obtained permission for conducting the field study|Organizing the field expedition	Organizing the field expedition	-	-	NO
4406746	25902058	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406746	25902058	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406746	25902058	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406746	25902058	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406746	25902058	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406746	25902058	PB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Studies on the herbarium specimens	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406746	25902058	PB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Studies on the herbarium specimens	Analyzed the data	Analyzed the data	Formal analysis	YES
4406746	25902058	PB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Studies on the herbarium specimens	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406746	25902058	PB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Studies on the herbarium specimens	Studies on the herbarium specimens	Performed the experiments	Investigation	YES
5517386	28726076	All the authors	2	have read, commented and accepted the manuscript	have read, commented and accepted the manuscript	-	-	NO
5517386	28726076	CT	2	imaging and analysis of the ct data	imaging and analysis of the ct data	Analyzed the data	Formal analysis|Visualization	YES
5517386	28726076	EH	2	carried out most of the spect acquisition and data analysis and also prepared the manuscript	carried out most of the spect acquisition and data analysis and also prepared the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5517386	28726076	The author	2	carried out most of the spect acquisition and data analysis and also prepared the manuscript	carried out most of the spect acquisition and data analysis and also prepared the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3676954	23766724	D. Li	2	participated in the project design	participated in the project design	Conceived and designed the experiments	Methodology	YES
3676954	23766724	J. Yong	2	carried out the studies, analyzed data, and drafted the paper	carried out the studies, analyzed data, and drafted the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3676954	23766724	N. Khan	2	carried out the studies, analyzed data, and drafted the paper	carried out the studies, analyzed data, and drafted the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3676954	23766724	T. Huang	2	carried out the studies, analyzed data, and drafted the paper|participated in the project design	carried out the studies, analyzed data, and drafted the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3676954	23766724	T. Huang	2	carried out the studies, analyzed data, and drafted the paper|participated in the project design	participated in the project design	Conceived and designed the experiments	Methodology	YES
3676954	23766724	X. Hu	2	carried out the studies, analyzed data, and drafted the paper	carried out the studies, analyzed data, and drafted the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5363057	28330454	CS	2	carried out most of the experiments and drafted the manuscript	carried out most of the experiments and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5363057	28330454	DZ	2	performed the snps validation experiment	performed the snps validation experiment	Performed the experiments	Investigation|Validation	YES
5363057	28330454	ZXL	2	conceived and instructed the project	conceived and instructed the project	Conceived and designed the experiments	Conceptualization|Supervision	YES
4515279	26247033	Chien-Chih Chen	2	contributed equally to this study	contributed equally to this study	-	-	NO
4515279	26247033	Ing-Kit Lee	2	contributed equally to this study	contributed equally to this study	-	-	NO
2733137	19678950	BFC	2	provided mentoring and extensive editing of the final manuscript	provided mentoring and extensive editing of the final manuscript	Wrote the paper	Writing - Review & Editing	YES
2733137	19678950	JGS	2	carried out the analysis and wrote the initial draft	carried out the analysis and wrote the initial draft	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
2733137	19678950	KCS	2	provided mentoring and extensive editing of the final manuscript	provided mentoring and extensive editing of the final manuscript	Wrote the paper	Writing - Review & Editing	YES
2733137	19678950	WLM	2	provided mentoring and extensive editing of the final manuscript	provided mentoring and extensive editing of the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5581942	28900433	All authors	2	read and approved the manuscript	read and approved the manuscript	-	-	NO
5581942	28900433	CS	2	initiated and designed the research|collected the materials and performed the experiments|analyzed the data and wrote the manuscript	initiated and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5581942	28900433	CS	2	initiated and designed the research|collected the materials and performed the experiments|analyzed the data and wrote the manuscript	collected the materials and performed the experiments	Performed the experiments	Investigation	YES
5581942	28900433	CS	2	initiated and designed the research|collected the materials and performed the experiments|analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5581942	28900433	GL	2	initiated and designed the research|obtained funding for this study|collected the materials and performed the experiments	initiated and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5581942	28900433	GL	2	initiated and designed the research|obtained funding for this study|collected the materials and performed the experiments	obtained funding for this study	-	Funding acquisition	YES
5581942	28900433	GL	2	initiated and designed the research|obtained funding for this study|collected the materials and performed the experiments	collected the materials and performed the experiments	Performed the experiments	Investigation	YES
5581942	28900433	SX	2	initiated and designed the research|obtained funding for this study|collected the materials and performed the experiments|analyzed the data and wrote the manuscript	initiated and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5581942	28900433	SX	2	initiated and designed the research|obtained funding for this study|collected the materials and performed the experiments|analyzed the data and wrote the manuscript	obtained funding for this study	-	Funding acquisition	YES
5581942	28900433	SX	2	initiated and designed the research|obtained funding for this study|collected the materials and performed the experiments|analyzed the data and wrote the manuscript	collected the materials and performed the experiments	Performed the experiments	Investigation	YES
5581942	28900433	SX	2	initiated and designed the research|obtained funding for this study|collected the materials and performed the experiments|analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5581942	28900433	ZC	2	analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4406747	25902359	AD	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406747	25902359	AD	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4406747	25902359	AD	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406747	25902359	CM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406747	25902359	CM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406747	25902359	CM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406747	25902359	CM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406747	25902359	CM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406747	25902359	LP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406747	25902359	LP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406747	25902359	LP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406747	25902359	LP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406747	25902359	LP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406747	25902359	SM	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406747	25902359	SM	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5559412	28815472	AC	2	participated in coregistration procedure	participated in coregistration procedure	Performed the experiments	Investigation	YES
5559412	28815472	ALG	2	contributed to the design of the study and have been involved in revising the manuscript critically for important intellectual content	contributed to the design of the study and have been involved in revising the manuscript critically for important intellectual content	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5559412	28815472	CAJ	2	was involved in patient selection and surgery	was involved in patient selection and surgery	Performed the experiments	Investigation	YES
5559412	28815472	CZ	2	were involved in coregistration procedure, data collection, statistical analysis, and drafting this paper	were involved in coregistration procedure, data collection, statistical analysis, and drafting this paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5559412	28815472	FS	2	were involved in coregistration procedure, data collection, statistical analysis, and drafting this paper	were involved in coregistration procedure, data collection, statistical analysis, and drafting this paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5559412	28815472	MM	2	contributed to the design of the study and have been involved in revising the manuscript critically for important intellectual content	contributed to the design of the study and have been involved in revising the manuscript critically for important intellectual content	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5559412	28815472	MW	2	conducted histopathological preparation	conducted histopathological preparation	Performed the experiments	Investigation	YES
5559412	28815472	NS	2	participated in coregistration procedure	participated in coregistration procedure	Performed the experiments	Investigation	YES
5559412	28815472	PTM	2	contributed to the design of the study and have been involved in revising the manuscript critically for important intellectual content	contributed to the design of the study and have been involved in revising the manuscript critically for important intellectual content	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5559412	28815472	TF	2	were involved in coregistration procedure, data collection, statistical analysis, and drafting this paper	were involved in coregistration procedure, data collection, statistical analysis, and drafting this paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5559412	28815472	VD	2	conducted histopathological preparation	conducted histopathological preparation	Performed the experiments	Investigation	YES
6170205	30294430	All authors	2	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
6170205	30294430	Annunziata Panebianco	2	contributed in collections, database, all figures and tables	contributed in collections, database, all figures and tables	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources|Software|Visualization	YES
6170205	30294430	Bianca Pascazio	2	contributed in collections, database, all figures and tables	contributed in collections, database, all figures and tables	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources|Software|Visualization	YES
6170205	30294430	Francesco Paolo Bianchi	2	prepared data analysis	prepared data analysis	Analyzed the data	Formal analysis	YES
6170205	30294430	Giovanni Balducci	2	contributed in collections, database, all figures and tables	contributed in collections, database, all figures and tables	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources|Software|Visualization	YES
6170205	30294430	Giuseppe Carbotta	2	wrote the main manuscript text	wrote the main manuscript text	Wrote the paper	Writing - Original Draft	YES
6170205	30294430	Nicola Palasciano	2	wrote the discussion	wrote the discussion	Wrote the paper	Writing - Original Draft	YES
6170205	30294430	Rita Laforgia	2	wrote the main manuscript text	wrote the main manuscript text	Wrote the paper	Writing - Original Draft	YES
6170205	30294430	Silvio Tafuri	2	prepared data analysis	prepared data analysis	Analyzed the data	Formal analysis	YES
2745426	19737406	All authors	2	participated in the preparation of the manuscript, and read and approved the final manuscript	participated in the preparation of the manuscript, and read and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5364565	28335728	HRH	2	contributed to the design of the research, performed computational simulations and analyzed data on the stability of the model in a larger system and drafted the manuscript	contributed to the design of the research, performed computational simulations and analyzed data on the stability of the model in a larger system and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
5364565	28335728	PP	2	contributed to the design of the research, performed the experiments, analyzed data on marker segregation, generated the linkage map and drafted the manuscript	contributed to the design of the research, performed the experiments, analyzed data on marker segregation, generated the linkage map and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
5364565	28335728	SB	2	conceived the study and drafted the manuscript	conceived the study and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5581943	28900431	GA	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5581943	28900431	GZ	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
5581943	28900431	GZ	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5581943	28900431	HW	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5581943	28900431	HW	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5581943	28900431	JY	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
5581943	28900431	JY	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5581943	28900431	MR	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5581943	28900431	QY	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5581943	28900431	RW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5581943	28900431	WB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
5581943	28900431	WB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5581943	28900431	WB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5581943	28900431	XP	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
5581943	28900431	XP	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5581943	28900431	XP	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5581943	28900431	YC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5581943	28900431	YC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
5581943	28900431	YC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5581943	28900431	ZL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5581943	28900431	ZY	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
6091363	30151285	Akua Addo Wiafe	2	helped in data collection and data analysis	helped in data collection and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6091363	30151285	Bright Amankwaa	2	helped in data collection and data analysis	helped in data collection and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6091363	30151285	Emmanuel Acheampong	2	helped in data collection and data analysis	helped in data collection and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6091363	30151285	K. D. Ephraim	2	helped in data collection and data analysis|contributed to critical revisions of manuscript	helped in data collection and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6091363	30151285	K. D. Ephraim	2	helped in data collection and data analysis|contributed to critical revisions of manuscript	contributed to critical revisions of manuscript	Wrote the paper	Writing - Review & Editing	YES
6091363	30151285	Linda Ahenkorah Fondjo	2	contributed to conception of idea|assisted in design and drafting of manuscript	contributed to conception of idea	Conceived and designed the experiments	Conceptualization	YES
6091363	30151285	Linda Ahenkorah Fondjo	2	contributed to conception of idea|assisted in design and drafting of manuscript	assisted in design and drafting of manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
6091363	30151285	Osei Owusu-Afriyie	2	contributed to conception of idea	contributed to conception of idea	Conceived and designed the experiments	Conceptualization	YES
6091363	30151285	Samuel Asamoah Sakyi	2	assisted in design and drafting of manuscript	assisted in design and drafting of manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
4406748	25902045	FL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406748	25902045	FL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406748	25902045	FL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406748	25902045	HC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406748	25902045	HH	PLoS5	Modified the format of the manuscript	Modified the format of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4406748	25902045	LG	PLoS5	Modified the format of the manuscript|Submitted the manuscript	Modified the format of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4406748	25902045	LG	PLoS5	Modified the format of the manuscript|Submitted the manuscript	Submitted the manuscript	-	-	NO
4406748	25902045	LT	PLoS5	Modified the format of the manuscript	Modified the format of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4406748	25902045	WP	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406748	25902045	XZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406748	25902045	XZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406748	25902045	XZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6170208	30294437	Dr Nozoe	2	help in conceptualizing and designing the study, analyzing the data, writing the manuscript and procuring funds	help in conceptualizing and designing the study, analyzing the data, writing the manuscript and procuring funds	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
6170208	30294437	Drs Nozoe	2	helped in the data collection	helped in the data collection	Performed the experiments	Investigation	YES
6170208	30294437	Ms Kamo	2	helped in the data collection	helped in the data collection	Performed the experiments	Investigation	YES
4515282	26247012	Na-Young Choi	2	are contributed equally to this paper	are contributed equally to this paper	-	-	NO
4515282	26247012	Sun-Young Kang	2	are contributed equally to this paper	are contributed equally to this paper	-	-	NO
5603470	28921170	HJI	2	contributed to the conception or design of the work|contributed to the acquisition, analysis, or interpretation of the data for the work	contributed to the conception or design of the work	Conceived and designed the experiments	Conceptualization	YES
5603470	28921170	HJI	2	contributed to the conception or design of the work|contributed to the acquisition, analysis, or interpretation of the data for the work	contributed to the acquisition, analysis, or interpretation of the data for the work	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5603470	28921170	IL	2	contributed to the conception or design of the work|contributed to the acquisition, analysis, or interpretation of the data for the work|contributed to drafting the work or revising it critically for important intellectual content	contributed to the conception or design of the work	Conceived and designed the experiments	Conceptualization	YES
5603470	28921170	IL	2	contributed to the conception or design of the work|contributed to the acquisition, analysis, or interpretation of the data for the work|contributed to drafting the work or revising it critically for important intellectual content	contributed to the acquisition, analysis, or interpretation of the data for the work	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5603470	28921170	IL	2	contributed to the conception or design of the work|contributed to the acquisition, analysis, or interpretation of the data for the work|contributed to drafting the work or revising it critically for important intellectual content	contributed to drafting the work or revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5603470	28921170	MS	2	contributed to the conception or design of the work|contributed to the acquisition, analysis, or interpretation of the data for the work|contributed to drafting the work or revising it critically for important intellectual content	contributed to the conception or design of the work	Conceived and designed the experiments	Conceptualization	YES
5603470	28921170	MS	2	contributed to the conception or design of the work|contributed to the acquisition, analysis, or interpretation of the data for the work|contributed to drafting the work or revising it critically for important intellectual content	contributed to the acquisition, analysis, or interpretation of the data for the work	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5603470	28921170	MS	2	contributed to the conception or design of the work|contributed to the acquisition, analysis, or interpretation of the data for the work|contributed to drafting the work or revising it critically for important intellectual content	contributed to drafting the work or revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5603470	28921170	SYC	2	contributed to the conception or design of the work|contributed to the acquisition, analysis, or interpretation of the data for the work|contributed to drafting the work or revising it critically for important intellectual content	contributed to the conception or design of the work	Conceived and designed the experiments	Conceptualization	YES
5603470	28921170	SYC	2	contributed to the conception or design of the work|contributed to the acquisition, analysis, or interpretation of the data for the work|contributed to drafting the work or revising it critically for important intellectual content	contributed to the acquisition, analysis, or interpretation of the data for the work	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5603470	28921170	SYC	2	contributed to the conception or design of the work|contributed to the acquisition, analysis, or interpretation of the data for the work|contributed to drafting the work or revising it critically for important intellectual content	contributed to drafting the work or revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4406749	25901359	CD	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406749	25901359	CD	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406749	25901359	CD	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406749	25901359	XK	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406749	25901359	YS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406749	25901359	YS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406749	25901359	YS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406749	25901359	YS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406749	25901359	YS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5582342	28912788	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5582342	28912788	FH	2	contributed to the gbs analysis	contributed to the gbs analysis	-	-	NO
5582342	28912788	GM	2	performed the genotyping	performed the genotyping	Performed the experiments	Investigation	YES
5582342	28912788	JP	2	planned the study|supervised the research|drafted the manuscript	planned the study	Conceived and designed the experiments	Conceptualization	YES
5582342	28912788	JP	2	planned the study|supervised the research|drafted the manuscript	supervised the research	-	Supervision	YES
5582342	28912788	JP	2	planned the study|supervised the research|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5582342	28912788	MP	2	performed the genotyping	performed the genotyping	Performed the experiments	Investigation	YES
5582342	28912788	PG	2	supervised the research|managed the seed collections|performed the genotyping|drafted the manuscript	supervised the research	-	Supervision	YES
5582342	28912788	PG	2	supervised the research|managed the seed collections|performed the genotyping|drafted the manuscript	managed the seed collections	-	-	NO
5582342	28912788	PG	2	supervised the research|managed the seed collections|performed the genotyping|drafted the manuscript	performed the genotyping	Performed the experiments	Investigation	YES
5582342	28912788	PG	2	supervised the research|managed the seed collections|performed the genotyping|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5582342	28912788	SV	2	planned the study|supervised the research|drafted the manuscript	planned the study	Conceived and designed the experiments	Conceptualization	YES
5582342	28912788	SV	2	planned the study|supervised the research|drafted the manuscript	supervised the research	-	Supervision	YES
5582342	28912788	SV	2	planned the study|supervised the research|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
2757028	19772617	JLM	2	attest they have made substantial contributions in drafting the manuscript and revising it critically for important intellectual content, that they have given final approval of the version to be published, and that they have participated sufficiently in the work to take public responsibility for appropriate portions of the content|read and approved the final manuscript	attest they have made substantial contributions in drafting the manuscript and revising it critically for important intellectual content, that they have given final approval of the version to be published, and that they have participated sufficiently in the work to take public responsibility for appropriate portions of the content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
2757028	19772617	JLM	2	attest they have made substantial contributions in drafting the manuscript and revising it critically for important intellectual content, that they have given final approval of the version to be published, and that they have participated sufficiently in the work to take public responsibility for appropriate portions of the content|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
2757028	19772617	JLV	2	attest they have made substantial contributions in drafting the manuscript and revising it critically for important intellectual content, that they have given final approval of the version to be published, and that they have participated sufficiently in the work to take public responsibility for appropriate portions of the content|read and approved the final manuscript	attest they have made substantial contributions in drafting the manuscript and revising it critically for important intellectual content, that they have given final approval of the version to be published, and that they have participated sufficiently in the work to take public responsibility for appropriate portions of the content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
2757028	19772617	JLV	2	attest they have made substantial contributions in drafting the manuscript and revising it critically for important intellectual content, that they have given final approval of the version to be published, and that they have participated sufficiently in the work to take public responsibility for appropriate portions of the content|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
2757028	19772617	MYR	2	attest they have made substantial contributions in drafting the manuscript and revising it critically for important intellectual content, that they have given final approval of the version to be published, and that they have participated sufficiently in the work to take public responsibility for appropriate portions of the content|read and approved the final manuscript	attest they have made substantial contributions in drafting the manuscript and revising it critically for important intellectual content, that they have given final approval of the version to be published, and that they have participated sufficiently in the work to take public responsibility for appropriate portions of the content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
2757028	19772617	MYR	2	attest they have made substantial contributions in drafting the manuscript and revising it critically for important intellectual content, that they have given final approval of the version to be published, and that they have participated sufficiently in the work to take public responsibility for appropriate portions of the content|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5364584	28335726	AW	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5364584	28335726	CK	PLoS52	designed research and coordinated the study|performed the experiments	designed research and coordinated the study	Conceived and designed the experiments	Methodology|Project administration	YES
5364584	28335726	CK	PLoS52	designed research and coordinated the study|performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5364584	28335726	DG	PLoS52	performed the experiments|analyzed the data and performed functional analysis of microarray data|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5364584	28335726	DG	PLoS52	performed the experiments|analyzed the data and performed functional analysis of microarray data|wrote the paper	analyzed the data and performed functional analysis of microarray data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5364584	28335726	DG	PLoS52	performed the experiments|analyzed the data and performed functional analysis of microarray data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5364584	28335726	GD	PLoS52	designed research and coordinated the study	designed research and coordinated the study	Conceived and designed the experiments	Methodology|Project administration	YES
5364584	28335726	GL	PLoS52	performed lipidomic analysis	performed lipidomic analysis	Performed the experiments	Investigation	YES
5364584	28335726	KE	PLoS52	designed research and coordinated the study|wrote the paper	designed research and coordinated the study	Conceived and designed the experiments	Methodology|Project administration	YES
5364584	28335726	KE	PLoS52	designed research and coordinated the study|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5364584	28335726	RR	PLoS52	analyzed the data and performed functional analysis of microarray data|wrote the paper	analyzed the data and performed functional analysis of microarray data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5364584	28335726	RR	PLoS52	analyzed the data and performed functional analysis of microarray data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6109514	30159172	A. Ntekim	2	did the data acquisition	did the data acquisition	Performed the experiments	Investigation	YES
6109514	30159172	All authors	2	approve of the final manuscript before publication	approve of the final manuscript before publication	Wrote the paper	Writing - Review & Editing	YES
6109514	30159172	D. B. Adamu	2	did the data acquisition|did the data analysis and reporting|wrote the draft manuscript	did the data acquisition	Performed the experiments	Investigation	YES
6109514	30159172	D. B. Adamu	2	did the data acquisition|did the data analysis and reporting|wrote the draft manuscript	did the data analysis and reporting	Analyzed the data	Formal analysis	YES
6109514	30159172	D. B. Adamu	2	did the data acquisition|did the data analysis and reporting|wrote the draft manuscript	wrote the draft manuscript	Wrote the paper	Writing - Original Draft	YES
6109514	30159172	M. D. Dairo	2	did the data analysis and reporting|wrote the draft manuscript	did the data analysis and reporting	Analyzed the data	Formal analysis	YES
6109514	30159172	M. D. Dairo	2	did the data analysis and reporting|wrote the draft manuscript	wrote the draft manuscript	Wrote the paper	Writing - Original Draft	YES
6109514	30159172	O. Ayeni	2	provided general supervision and direction for the study	provided general supervision and direction for the study	-	Supervision	YES
6109514	30159172	Y. A. Onimode	2	wrote the draft manuscript	wrote the draft manuscript	Wrote the paper	Writing - Original Draft	YES
5603471	28924696	Each author	2	should have participated sufficiently in the work to take public responsibility for appropriate portions of the content	should have participated sufficiently in the work to take public responsibility for appropriate portions of the content	-	-	NO
5603471	28924696	IH	2	made substantial contributions to conception and design, or acquisition of data, or analysis and interpretation of data|have been involved in drafting the manuscript or revising it critically for important intellectual content|gave final approval of the version to be published|agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	made substantial contributions to conception and design, or acquisition of data, or analysis and interpretation of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
5603471	28924696	IH	2	made substantial contributions to conception and design, or acquisition of data, or analysis and interpretation of data|have been involved in drafting the manuscript or revising it critically for important intellectual content|gave final approval of the version to be published|agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	have been involved in drafting the manuscript or revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5603471	28924696	IH	2	made substantial contributions to conception and design, or acquisition of data, or analysis and interpretation of data|have been involved in drafting the manuscript or revising it critically for important intellectual content|gave final approval of the version to be published|agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	gave final approval of the version to be published	-	-	NO
5603471	28924696	IH	2	made substantial contributions to conception and design, or acquisition of data, or analysis and interpretation of data|have been involved in drafting the manuscript or revising it critically for important intellectual content|gave final approval of the version to be published|agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	-	-	NO
5603471	28924696	LKS	2	have been involved in drafting the manuscript or revising it critically for important intellectual content|gave final approval of the version to be published|agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	have been involved in drafting the manuscript or revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5603471	28924696	LKS	2	have been involved in drafting the manuscript or revising it critically for important intellectual content|gave final approval of the version to be published|agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	gave final approval of the version to be published	-	-	NO
5603471	28924696	LKS	2	have been involved in drafting the manuscript or revising it critically for important intellectual content|gave final approval of the version to be published|agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	-	-	NO
5603471	28924696	OSH	2	have been involved in drafting the manuscript or revising it critically for important intellectual content|gave final approval of the version to be published|agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	have been involved in drafting the manuscript or revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5603471	28924696	OSH	2	have been involved in drafting the manuscript or revising it critically for important intellectual content|gave final approval of the version to be published|agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	gave final approval of the version to be published	-	-	NO
5603471	28924696	OSH	2	have been involved in drafting the manuscript or revising it critically for important intellectual content|gave final approval of the version to be published|agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	-	-	NO
5603471	28924696	PG	2	have been involved in drafting the manuscript or revising it critically for important intellectual content|gave final approval of the version to be published|agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	have been involved in drafting the manuscript or revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5603471	28924696	PG	2	have been involved in drafting the manuscript or revising it critically for important intellectual content|gave final approval of the version to be published|agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	gave final approval of the version to be published	-	-	NO
5603471	28924696	PG	2	have been involved in drafting the manuscript or revising it critically for important intellectual content|gave final approval of the version to be published|agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	-	-	NO
5603471	28924696	RB	2	made substantial contributions to conception and design, or acquisition of data, or analysis and interpretation of data|have been involved in drafting the manuscript or revising it critically for important intellectual content|gave final approval of the version to be published|agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	made substantial contributions to conception and design, or acquisition of data, or analysis and interpretation of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
5603471	28924696	RB	2	made substantial contributions to conception and design, or acquisition of data, or analysis and interpretation of data|have been involved in drafting the manuscript or revising it critically for important intellectual content|gave final approval of the version to be published|agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	have been involved in drafting the manuscript or revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5603471	28924696	RB	2	made substantial contributions to conception and design, or acquisition of data, or analysis and interpretation of data|have been involved in drafting the manuscript or revising it critically for important intellectual content|gave final approval of the version to be published|agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	gave final approval of the version to be published	-	-	NO
5603471	28924696	RB	2	made substantial contributions to conception and design, or acquisition of data, or analysis and interpretation of data|have been involved in drafting the manuscript or revising it critically for important intellectual content|gave final approval of the version to be published|agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	-	-	NO
5603471	28924696	SS	2	have been involved in drafting the manuscript or revising it critically for important intellectual content|gave final approval of the version to be published|agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	have been involved in drafting the manuscript or revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5603471	28924696	SS	2	have been involved in drafting the manuscript or revising it critically for important intellectual content|gave final approval of the version to be published|agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	gave final approval of the version to be published	-	-	NO
5603471	28924696	SS	2	have been involved in drafting the manuscript or revising it critically for important intellectual content|gave final approval of the version to be published|agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	-	-	NO
5603471	28924696	WJGO	2	made substantial contributions to conception and design, or acquisition of data, or analysis and interpretation of data|have been involved in drafting the manuscript or revising it critically for important intellectual content|gave final approval of the version to be published|agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	made substantial contributions to conception and design, or acquisition of data, or analysis and interpretation of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
5603471	28924696	WJGO	2	made substantial contributions to conception and design, or acquisition of data, or analysis and interpretation of data|have been involved in drafting the manuscript or revising it critically for important intellectual content|gave final approval of the version to be published|agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	have been involved in drafting the manuscript or revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5603471	28924696	WJGO	2	made substantial contributions to conception and design, or acquisition of data, or analysis and interpretation of data|have been involved in drafting the manuscript or revising it critically for important intellectual content|gave final approval of the version to be published|agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	gave final approval of the version to be published	-	-	NO
5603471	28924696	WJGO	2	made substantial contributions to conception and design, or acquisition of data, or analysis and interpretation of data|have been involved in drafting the manuscript or revising it critically for important intellectual content|gave final approval of the version to be published|agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	-	-	NO
5603471	28924696	YL	2	have been involved in drafting the manuscript or revising it critically for important intellectual content|gave final approval of the version to be published|agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	have been involved in drafting the manuscript or revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5603471	28924696	YL	2	have been involved in drafting the manuscript or revising it critically for important intellectual content|gave final approval of the version to be published|agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	gave final approval of the version to be published	-	-	NO
5603471	28924696	YL	2	have been involved in drafting the manuscript or revising it critically for important intellectual content|gave final approval of the version to be published|agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	-	-	NO
4406750	25901943	BB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406750	25901943	BB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4406750	25901943	BB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4406750	25901943	BB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406750	25901943	DLB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406750	25901943	DLB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4406750	25901943	DLB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4406750	25901943	DLB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406750	25901943	GSF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406750	25901943	GSF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406750	25901943	GSF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406750	25901943	JWW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406750	25901943	JWW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406750	25901943	JWW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406750	25901943	JWW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406750	25901943	JWW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406750	25901943	SG	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406750	25901943	STB	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406750	25901943	WW	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406750	25901943	WW	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5582351	28912789	FM	PLoS52	performed the analysis	performed the analysis	Performed the experiments	Investigation	YES
5582351	28912789	JW	PLoS52	implemented and coordinated the analyses|performed the analysis|wrote the paper	implemented and coordinated the analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Project administration	YES
5582351	28912789	JW	PLoS52	implemented and coordinated the analyses|performed the analysis|wrote the paper	performed the analysis	Performed the experiments	Investigation	YES
5582351	28912789	JW	PLoS52	implemented and coordinated the analyses|performed the analysis|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5582351	28912789	JY	PLoS52	performed the analysis	performed the analysis	Performed the experiments	Investigation	YES
5582351	28912789	LW	PLoS52	performed the analysis	performed the analysis	Performed the experiments	Investigation	YES
5582351	28912789	NY	PLoS52	performed the analysis	performed the analysis	Performed the experiments	Investigation	YES
5582351	28912789	RX	PLoS52	performed the analysis	performed the analysis	Performed the experiments	Investigation	YES
5582351	28912789	SS	PLoS52	implemented and coordinated the analyses|performed the analysis|wrote the paper	implemented and coordinated the analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Project administration	YES
5582351	28912789	SS	PLoS52	implemented and coordinated the analyses|performed the analysis|wrote the paper	performed the analysis	Performed the experiments	Investigation	YES
5582351	28912789	SS	PLoS52	implemented and coordinated the analyses|performed the analysis|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5582351	28912789	WG	PLoS52	performed the analysis	performed the analysis	Performed the experiments	Investigation	YES
5582351	28912789	XL	PLoS52	performed the analysis	performed the analysis	Performed the experiments	Investigation	YES
5582351	28912789	XW	PLoS52	conceived the study and led the research|wrote the paper	conceived the study and led the research	Conceived and designed the experiments	Conceptualization	YES
5582351	28912789	XW	PLoS52	conceived the study and led the research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5582351	28912789	YLi	PLoS52	performed the analysis	performed the analysis	Performed the experiments	Investigation	YES
5582351	28912789	YLiu	PLoS52	performed the analysis	performed the analysis	Performed the experiments	Investigation	YES
5582351	28912789	ZW	PLoS52	performed the analysis	performed the analysis	Performed the experiments	Investigation	YES
6170934	30294442	AAA	2	participated in concept, study design, data collection, and literature search	participated in concept, study design, data collection, and literature search	Conceived and designed the experiments|Performed the experiments	Conceptualization|Formal analysis|Investigation|Methodology	YES
6170934	30294442	All	2	authors read and approved the final manuscript	authors read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6170934	30294442	All authors	2	participated in concept, study design, data collection, and literature search	participated in concept, study design, data collection, and literature search	Conceived and designed the experiments|Performed the experiments	Conceptualization|Formal analysis|Investigation|Methodology	YES
6170934	30294442	MN	2	participated in concept, study design, data collection, and literature search	participated in concept, study design, data collection, and literature search	Conceived and designed the experiments|Performed the experiments	Conceptualization|Formal analysis|Investigation|Methodology	YES
6170934	30294442	MSQ	2	participated in concept, study design, data collection, and literature search|authors read and approved the final manuscript	participated in concept, study design, data collection, and literature search	Conceived and designed the experiments|Performed the experiments	Conceptualization|Formal analysis|Investigation|Methodology	YES
6170934	30294442	MSQ	2	participated in concept, study design, data collection, and literature search|authors read and approved the final manuscript	authors read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6170934	30294442	MYD	2	participated in concept, study design, data collection, and literature search|authors read and approved the final manuscript	participated in concept, study design, data collection, and literature search	Conceived and designed the experiments|Performed the experiments	Conceptualization|Formal analysis|Investigation|Methodology	YES
6170934	30294442	MYD	2	participated in concept, study design, data collection, and literature search|authors read and approved the final manuscript	authors read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6170934	30294442	SQ	2	participated in concept, study design, data collection, and literature search	participated in concept, study design, data collection, and literature search	Conceived and designed the experiments|Performed the experiments	Conceptualization|Formal analysis|Investigation|Methodology	YES
6170934	30294442	SSA	2	participated in concept, study design, data collection, and literature search	participated in concept, study design, data collection, and literature search	Conceived and designed the experiments|Performed the experiments	Conceptualization|Formal analysis|Investigation|Methodology	YES
5640560	29030760	AC	2	contributed to the design of this work|analyzed the data, performed dosimetry calculations, and wrote the manuscript	contributed to the design of this work	Conceived and designed the experiments	-	YES
5640560	29030760	AC	2	contributed to the design of this work|analyzed the data, performed dosimetry calculations, and wrote the manuscript	analyzed the data, performed dosimetry calculations, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5640560	29030760	All authors	2	contributed to the design of this work	contributed to the design of this work	Conceived and designed the experiments	-	YES
5640560	29030760	BB	2	contributed to the design of this work|were responsible for patient recruitment, imaging studies, and interpretation of images	contributed to the design of this work	Conceived and designed the experiments	-	YES
5640560	29030760	BB	2	contributed to the design of this work|were responsible for patient recruitment, imaging studies, and interpretation of images	were responsible for patient recruitment, imaging studies, and interpretation of images	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
5640560	29030760	HP-B	2	contributed to the design of this work|were responsible for patient recruitment, imaging studies, and interpretation of images	contributed to the design of this work	Conceived and designed the experiments	-	YES
5640560	29030760	HP-B	2	contributed to the design of this work|were responsible for patient recruitment, imaging studies, and interpretation of images	were responsible for patient recruitment, imaging studies, and interpretation of images	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
5640560	29030760	XH	2	contributed to the design of this work|analyzed the data, performed dosimetry calculations, and wrote the manuscript	contributed to the design of this work	Conceived and designed the experiments	-	YES
5640560	29030760	XH	2	contributed to the design of this work|analyzed the data, performed dosimetry calculations, and wrote the manuscript	analyzed the data, performed dosimetry calculations, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4406752	25901575	IR	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406752	25901575	IR	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406752	25901575	IR	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406752	25901575	JB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406752	25901575	JB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406752	25901575	JB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406752	25901575	JB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406752	25901575	PKS	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406752	25901575	PKS	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6174843	30302243	Pradeep Goyal	7	Writing paper, reviewing images	Writing paper, reviewing images	Analyzed the data|Wrote the paper	Visualization|Writing - Original Draft|Writing - Review & Editing	YES
6174843	30302243	Pranav Sharma	7	Writing paper	Writing paper	Wrote the paper	Writing - Original Draft	YES
6174843	30302243	Priti Soni	7	Interpreting pathology slides, reviewing paper. Puneet	Interpreting pathology slides, reviewing paper. Puneet	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
6174843	30302243	S Kochar	7	Reviewing paper, editing	Reviewing paper, editing	Wrote the paper	Writing - Review & Editing	YES
6174843	30302243	Sonali Gupta	7	Writing paper	Writing paper	Wrote the paper	Writing - Original Draft	YES
2823620	20089202	Both authors	2	contributed equally to this work	contributed equally to this work	-	-	NO
5582365	28912796	AE	2	wrote python scripts for visualizing ninhydrin signal concentrations and helped prepare the related figure	wrote python scripts for visualizing ninhydrin signal concentrations and helped prepare the related figure	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Software|Visualization|Writing - Original Draft	YES
5582365	28912796	AH	2	drafted and revised the article including preparation of figures, gave intellectual contributions, improvements, and revisions	drafted and revised the article including preparation of figures, gave intellectual contributions, improvements, and revisions	Wrote the paper	Visualization|Writing - Original Draft|Writing - Review & Editing	YES
5582365	28912796	CW	2	drafted and revised the article including preparation of figures, gave intellectual contributions, improvements, and revisions	drafted and revised the article including preparation of figures, gave intellectual contributions, improvements, and revisions	Wrote the paper	Visualization|Writing - Original Draft|Writing - Review & Editing	YES
5582365	28912796	DT	2	wrote python scripts for visualizing ninhydrin signal concentrations and helped prepare the related figure	wrote python scripts for visualizing ninhydrin signal concentrations and helped prepare the related figure	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Software|Visualization|Writing - Original Draft	YES
5582365	28912796	ED	2	drafted and revised the article including preparation of figures, gave intellectual contributions, improvements, and revisions	drafted and revised the article including preparation of figures, gave intellectual contributions, improvements, and revisions	Wrote the paper	Visualization|Writing - Original Draft|Writing - Review & Editing	YES
5582365	28912796	MK	2	made substantial contributions to the study concept and design, ninhydrin paper preparation, image data collection process, and handled manuscript preparation including preparation of figures and references, gave intellectual contributions, improvements and revisions	made substantial contributions to the study concept and design, ninhydrin paper preparation, image data collection process, and handled manuscript preparation including preparation of figures and references, gave intellectual contributions, improvements and revisions	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Data curation|Investigation|Methodology|Resources|Visualization|Writing - Original Draft|Writing - Review & Editing	YES
5582365	28912796	TAD	2	made substantial contributions to the study concept and design, ninhydrin paper preparation, seedling growth, image data collection and analysis, prepared figures and references, and provided relative interpretation	made substantial contributions to the study concept and design, ninhydrin paper preparation, seedling growth, image data collection and analysis, prepared figures and references, and provided relative interpretation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Methodology|Resources|Visualization	YES
5582365	28912796	TDB	2	conceived and supervised the research in all aspects and made significant intellectual contributions in outlining the article, article content, and critically revising the article for final submission	conceived and supervised the research in all aspects and made significant intellectual contributions in outlining the article, article content, and critically revising the article for final submission	Conceived and designed the experiments|Wrote the paper	Conceptualization|Supervision|Writing - Review & Editing	YES
5582365	28912796	THD	2	made substantial contributions to the study concept and design, ninhydrin paper preparation, seedling growth, image data collection and analysis, prepared figures and references, and provided relative interpretation	made substantial contributions to the study concept and design, ninhydrin paper preparation, seedling growth, image data collection and analysis, prepared figures and references, and provided relative interpretation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Methodology|Resources|Visualization	YES
6186330	30363973	Delisha A. Stewart	2	contributed equally to work and are co-first authors	contributed equally to work and are co-first authors	-	-	NO
6186330	30363973	Jason H. Winnike	2	contributed equally to work and are co-first authors	contributed equally to work and are co-first authors	-	-	NO
6174863	30302244	Eisaku Ito	CRediT	Operations	Operations	Performed the experiments	Investigation	YES
6174863	30302244	Hironori Ohdaira	CRediT	Operations	Operations	Performed the experiments	Investigation	YES
6174863	30302244	Masaki Kitajima	CRediT	Supervision	Supervision	-	Supervision	YES
6174863	30302244	Masashi Yoshida	CRediT	Study conception and design	Study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6174863	30302244	Nobuhiro Tsutsui	CRediT	Study conception and design|Data collection, data analysis, and writing the paper|Operations	Study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6174863	30302244	Nobuhiro Tsutsui	CRediT	Study conception and design|Data collection, data analysis, and writing the paper|Operations	Data collection, data analysis, and writing the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6174863	30302244	Nobuhiro Tsutsui	CRediT	Study conception and design|Data collection, data analysis, and writing the paper|Operations	Operations	Performed the experiments	Investigation	YES
6174863	30302244	Yutaka Suzuki	CRediT	Critical revision	Critical revision	Wrote the paper	Writing - Review & Editing	YES
5364592	28335720	DCK	2	prepared the samples for the arrays	prepared the samples for the arrays	Performed the experiments	Investigation	YES
5364592	28335720	DP	2	conducted the hfs	conducted the hfs	Performed the experiments	Investigation	YES
5364592	28335720	JLVM	2	designed the experiments|designed the array, and conducted the bioinformatic analysis|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5364592	28335720	JLVM	2	designed the experiments|designed the array, and conducted the bioinformatic analysis|wrote the manuscript	designed the array, and conducted the bioinformatic analysis	Conceived and designed the experiments|Performed the experiments	Formal analysis|Investigation	YES
5364592	28335720	JLVM	2	designed the experiments|designed the array, and conducted the bioinformatic analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5364592	28335720	KW	2	designed the experiments|extracted the dna	designed the experiments	Conceived and designed the experiments	Methodology	YES
5364592	28335720	KW	2	designed the experiments|extracted the dna	extracted the dna	Performed the experiments	Investigation	YES
5364592	28335720	MED	2	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5364592	28335720	TP	2	helped with the statistical analysis	helped with the statistical analysis	Analyzed the data	Formal analysis	YES
2825495	20109176	Both authors	2	contributed to the writing and critical revision of the manuscript	contributed to the writing and critical revision of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5663990	29090358	AS	2	developed the proposed method|helped to interpret and discuss the results|revised the manuscript	developed the proposed method	Conceived and designed the experiments|Performed the experiments	Conceptualization|Methodology	YES
5663990	29090358	AS	2	developed the proposed method|helped to interpret and discuss the results|revised the manuscript	helped to interpret and discuss the results	Analyzed the data	Formal analysis	YES
5663990	29090358	AS	2	developed the proposed method|helped to interpret and discuss the results|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5663990	29090358	NA	2	collected the patient data and analyzed corresponding results|helped to interpret and discuss the results	collected the patient data and analyzed corresponding results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5663990	29090358	NA	2	collected the patient data and analyzed corresponding results|helped to interpret and discuss the results	helped to interpret and discuss the results	Analyzed the data	Formal analysis	YES
5663990	29090358	NS	2	developed the proposed method|implemented the algorithm, performed the data analysis, contributed to interpretation and discussion of results and drafted the manuscript	developed the proposed method	Conceived and designed the experiments|Performed the experiments	Conceptualization|Methodology	YES
5663990	29090358	NS	2	developed the proposed method|implemented the algorithm, performed the data analysis, contributed to interpretation and discussion of results and drafted the manuscript	implemented the algorithm, performed the data analysis, contributed to interpretation and discussion of results and drafted the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Software|Writing - Original Draft	YES
5663990	29090358	PS	2	helped to interpret and discuss the results	helped to interpret and discuss the results	Analyzed the data	Formal analysis	YES
5663990	29090358	ST	2	collected the patient data and analyzed corresponding results	collected the patient data and analyzed corresponding results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5582597	28912794	GH	2	assisted py performed most of the experiments, with	assisted py performed most of the experiments, with	Performed the experiments	Investigation	YES
5582597	28912794	HX	2	assisted py performed most of the experiments, with	assisted py performed most of the experiments, with	Performed the experiments	Investigation	YES
5582597	28912794	JM	2	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5582597	28912794	LX	2	assisted py performed most of the experiments, with	assisted py performed most of the experiments, with	Performed the experiments	Investigation	YES
5582597	28912794	PY	2	performed most of the experiments, with	performed most of the experiments, with	Performed the experiments	Investigation	YES
5582597	28912794	SY	2	assisted py performed most of the experiments, with	assisted py performed most of the experiments, with	Performed the experiments	Investigation	YES
5582597	28912794	YC	2	assisted py performed most of the experiments, with	assisted py performed most of the experiments, with	Performed the experiments	Investigation	YES
5582597	28912794	YF	2	assisted py performed most of the experiments, with	assisted py performed most of the experiments, with	Performed the experiments	Investigation	YES
5582597	28912794	YT	2	assisted py performed most of the experiments, with	assisted py performed most of the experiments, with	Performed the experiments	Investigation	YES
4406754	25902049	HMZ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406754	25902049	HMZ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406754	25902049	HMZ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406754	25902049	LW	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406754	25902049	TTL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4406754	25902049	TTL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4406754	25902049	TTL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406754	25902049	YPZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4406754	25902049	ZGE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406754	25902049	ZGE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406754	25902049	ZGE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406754	25902049	ZGE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406754	25902049	ZGE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2828974	20082703	JA	2	originated the article, did the research and wrote a first rough draft of the manuscript	originated the article, did the research and wrote a first rough draft of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
2828974	20082703	R. They	2	have both read and approved the final version of the manuscript	have both read and approved the final version of the manuscript	-	-	NO
2828974	20082703	SR	2	read the first version and contributed editorial and critical suggestions	read the first version and contributed editorial and critical suggestions	-	-	NO
4241326	25431660	All authors	2	contributed to the writing of the paper and approved the final paper	contributed to the writing of the paper and approved the final paper	Wrote the paper	Writing - Original Draft	YES
4241326	25431660	Endalew Zemene	2	participated in the study design, data acquisition, and data analysis	participated in the study design, data acquisition, and data analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
4241326	25431660	Serkadis Debalke	2	participated in the study design, data acquisition, and data analysis	participated in the study design, data acquisition, and data analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
4241326	25431660	Tsegaye Yohanes	2	conceived the study and participated in the study design and data analysis	conceived the study and participated in the study design and data analysis	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
6204190	30405916	Allison E. Withers	2	contributed equally to this manuscript and are co-first authors	contributed equally to this manuscript and are co-first authors	-	-	NO
6204190	30405916	Ashley J. Schlafstein	2	contributed equally to this manuscript and are co-first authors	contributed equally to this manuscript and are co-first authors	-	-	NO
6204190	30405916	Soumon Rudra	2	contributed equally to this manuscript and are co-first authors	contributed equally to this manuscript and are co-first authors	-	-	NO
6224334	30425829	AA	PLoS52	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
6224334	30425829	HA	PLoS52	designed the study|collect the data and follow the patients during the hospitalization	designed the study	Conceived and designed the experiments	Methodology	YES
6224334	30425829	HA	PLoS52	designed the study|collect the data and follow the patients during the hospitalization	collect the data and follow the patients during the hospitalization	Performed the experiments	Investigation	YES
6224334	30425829	MMDF	PLoS52	designed the study|collect the data and follow the patients during the hospitalization	designed the study	Conceived and designed the experiments	Methodology	YES
6224334	30425829	MMDF	PLoS52	designed the study|collect the data and follow the patients during the hospitalization	collect the data and follow the patients during the hospitalization	Performed the experiments	Investigation	YES
6224334	30425829	MR	PLoS52	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
6224334	30425829	RN	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
6224334	30425829	SZ	PLoS52	collect the data and follow the patients during the hospitalization	collect the data and follow the patients during the hospitalization	Performed the experiments	Investigation	YES
5686036	29138942	All authors	2	contributed substantially to the work presented in this paper	contributed substantially to the work presented in this paper	-	-	NO
5686036	29138942	CW	2	contributed to the analysis of data and revising of the manuscript	contributed to the analysis of data and revising of the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
5686036	29138942	FAF	2	contributed to the design of the work and revising of the manuscript	contributed to the design of the work and revising of the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Review & Editing	YES
5686036	29138942	JN	2	contributed to the analysis and interpretation of data and drafting of the manuscript	contributed to the analysis and interpretation of data and drafting of the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
5686036	29138942	JS	2	contributed to the design and supervised the project	contributed to the design and supervised the project	Conceived and designed the experiments	Methodology|Supervision	YES
5686036	29138942	ML	2	contributed to the design and supervised the project	contributed to the design and supervised the project	Conceived and designed the experiments	Methodology|Supervision	YES
5686036	29138942	TK	2	contributed to the data acquisition, analysis and interpretation of data and revising of the manuscript	contributed to the data acquisition, analysis and interpretation of data and revising of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
5686036	29138942	VUer	2	contributed to the interpretation of data and revising of the manuscript	contributed to the interpretation of data and revising of the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
5364608	28335731	CKY	PLoS52	conceived and designed the study|collected the samples|performed the experiments|analyzed the data and drafted the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5364608	28335731	CKY	PLoS52	conceived and designed the study|collected the samples|performed the experiments|analyzed the data and drafted the manuscript	collected the samples	Performed the experiments	Investigation	YES
5364608	28335731	CKY	PLoS52	conceived and designed the study|collected the samples|performed the experiments|analyzed the data and drafted the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5364608	28335731	CKY	PLoS52	conceived and designed the study|collected the samples|performed the experiments|analyzed the data and drafted the manuscript	analyzed the data and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5364608	28335731	EH	PLoS52	performed the experiments|analyzed the data and drafted the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5364608	28335731	EH	PLoS52	performed the experiments|analyzed the data and drafted the manuscript	analyzed the data and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5364608	28335731	JM	PLoS52	conceived and designed the study|analyzed the data and drafted the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5364608	28335731	JM	PLoS52	conceived and designed the study|analyzed the data and drafted the manuscript	analyzed the data and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5364608	28335731	MVR	PLoS52	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5364608	28335731	MZ	PLoS52	performed the experiments|analyzed the data and drafted the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5364608	28335731	MZ	PLoS52	performed the experiments|analyzed the data and drafted the manuscript	analyzed the data and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5364608	28335731	NCN	PLoS52	performed the experiments|analyzed the data and drafted the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5364608	28335731	NCN	PLoS52	performed the experiments|analyzed the data and drafted the manuscript	analyzed the data and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5364608	28335731	NJK	PLoS52	analyzed the data and drafted the manuscript	analyzed the data and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5364608	28335731	PM	PLoS52	analyzed the data and drafted the manuscript	analyzed the data and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5364608	28335731	RZ	PLoS52	analyzed the data and drafted the manuscript	analyzed the data and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5364608	28335731	SMG	PLoS52	conceived and designed the study|collected the samples	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5364608	28335731	SMG	PLoS52	conceived and designed the study|collected the samples	collected the samples	Performed the experiments	Investigation	YES
5364608	28335731	WD	PLoS52	analyzed the data and drafted the manuscript	analyzed the data and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6279982	30555691	Imtiaz Nawaz	2	helped in editing the article	helped in editing the article	Wrote the paper	Writing - Review & Editing	YES
4406755	25901743	DG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406755	25901743	DG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406755	25901743	DG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406755	25901743	DG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406755	25901743	PS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406755	25901743	PS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406755	25901743	PS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406755	25901743	PS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406755	25901743	TP	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406755	25901743	TP	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406755	25901743	YI	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406755	25901743	YI	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5583216	28912786	CZ	7	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5583216	28912786	JH	7	designed the study, oversaw the research and co-wrote the manuscript	designed the study, oversaw the research and co-wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Original Draft	YES
5583216	28912786	JS	7	collected data and carried out all data analyses	collected data and carried out all data analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5583216	28912786	SF	7	performed the laboratory experiments and drafted the manuscript|collected data and carried out all data analyses	performed the laboratory experiments and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5583216	28912786	SF	7	performed the laboratory experiments and drafted the manuscript|collected data and carried out all data analyses	collected data and carried out all data analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
2841081	20184769	AR	2	prepared the first draft of the manuscript	prepared the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
2841081	20184769	CB	2	reviewed the first draft of the manuscript and made significant amends in regard of its content and structure|thoroughly discussed the ideas within the paper and agreed in the final version of the manuscript	reviewed the first draft of the manuscript and made significant amends in regard of its content and structure	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
2841081	20184769	CB	2	reviewed the first draft of the manuscript and made significant amends in regard of its content and structure|thoroughly discussed the ideas within the paper and agreed in the final version of the manuscript	thoroughly discussed the ideas within the paper and agreed in the final version of the manuscript	Conceived and designed the experiments	Conceptualization	YES
5698234	29164483	All authors	2	contributed to the design and draft of the manuscript	contributed to the design and draft of the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
6287372	30568792	ClementinM	2	contributed by conceptualization and revision of the manuscript	contributed by conceptualization and revision of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5364625	28335738	JST	2	contributed to the overall study design and writing the manuscript	contributed to the overall study design and writing the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5364625	28335738	MN	2	carried out the data analysis	carried out the data analysis	Analyzed the data	Formal analysis	YES
4406757	25901595	CMD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406757	25901595	CMD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406757	25901595	CMD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406757	25901595	JS	PLoS5	Conceived and designed the experiments|Contributed with ideas and with the analyses	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406757	25901595	JS	PLoS5	Conceived and designed the experiments|Contributed with ideas and with the analyses	Contributed with ideas and with the analyses	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
4406757	25901595	SHPO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406757	25901595	SHPO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406757	25901595	SHPO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406757	25901595	SHPO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5707214	29188397	JF	2	provided guidance on study design, data analysis, and article content	provided guidance on study design, data analysis, and article content	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Methodology|Resources|Supervision	YES
5707214	29188397	JT	2	designed the study, conducted the analysis, and wrote the article	designed the study, conducted the analysis, and wrote the article	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5583597	28912787	ES-V	2	leaded and all authors performed the experiment|the data processing and statistical analyses|produced the results and a first draft, and all authors substantially contributed to subsequent revisions	leaded and all authors performed the experiment	Performed the experiments	Investigation	YES
5583597	28912787	ES-V	2	leaded and all authors performed the experiment|the data processing and statistical analyses|produced the results and a first draft, and all authors substantially contributed to subsequent revisions	the data processing and statistical analyses	Analyzed the data	Data curation|Formal analysis	YES
5583597	28912787	ES-V	2	leaded and all authors performed the experiment|the data processing and statistical analyses|produced the results and a first draft, and all authors substantially contributed to subsequent revisions	produced the results and a first draft, and all authors substantially contributed to subsequent revisions	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5583597	28912787	LS	2	designed the study and provided the resources required for performing the research	designed the study and provided the resources required for performing the research	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources	YES
5583597	28912787	RZ	2	designed the study and provided the resources required for performing the research|the data processing and statistical analyses|produced the results and a first draft, and all authors substantially contributed to subsequent revisions	designed the study and provided the resources required for performing the research	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources	YES
5583597	28912787	RZ	2	designed the study and provided the resources required for performing the research|the data processing and statistical analyses|produced the results and a first draft, and all authors substantially contributed to subsequent revisions	the data processing and statistical analyses	Analyzed the data	Data curation|Formal analysis	YES
5583597	28912787	RZ	2	designed the study and provided the resources required for performing the research|the data processing and statistical analyses|produced the results and a first draft, and all authors substantially contributed to subsequent revisions	produced the results and a first draft, and all authors substantially contributed to subsequent revisions	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
2876986	20438627	JF	2	was lead investigator on the study on which this paper draws|who contributed equally to the final manuscript	was lead investigator on the study on which this paper draws	-	-	NO
2876986	20438627	JF	2	was lead investigator on the study on which this paper draws|who contributed equally to the final manuscript	who contributed equally to the final manuscript	Wrote the paper	Writing - Review & Editing	YES
2876986	20438627	VP	2	who contributed equally to the final manuscript	who contributed equally to the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6287373	30568793	Maryam Shahabi	7	writing the paper, study concept or design, data collection, data analysis and data interpretation	writing the paper, study concept or design, data collection, data analysis and data interpretation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
6287373	30568793	Noushin Kohan	7	writing the paper, data analysis or interpretation	writing the paper, data analysis or interpretation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6287373	30568793	Rafaat Bagherzadeh	7	writing the paper, data analysis or interpretation	writing the paper, data analysis or interpretation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6287373	30568793	Soleiman Ahmady	7	writing the paper, study concept or design, data collection, data analysis and data interpretation	writing the paper, study concept or design, data collection, data analysis and data interpretation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
6287373	30568793	Tayebeh Rakhshani	7	writing the paper, data analysis	writing the paper, data analysis	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
2878290	20459835	All authors	2	have equally contributed, read and approved the final manuscript	have equally contributed, read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
2878290	20459835	KS	2	compiled, formatted and submitted the manuscript	compiled, formatted and submitted the manuscript	-	-	NO
2878290	20459835	MM	2	founded the event	founded the event	-	-	NO
2878290	20459835	MN	2	organized the conference	organized the conference	-	-	NO
2878290	20459835	SB	2	organized the conference|founded the event	organized the conference	-	-	NO
2878290	20459835	SB	2	organized the conference|founded the event	founded the event	-	-	NO
6287572	30568794	Every Author	2	contributed equally	contributed equally	-	-	NO
4406758	25902146	DCM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Edited the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406758	25902146	DCM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Edited the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4406758	25902146	DCM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Edited the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4406758	25902146	DCM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Edited the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406758	25902146	DCM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Edited the manuscript	Edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
4406758	25902146	MB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Edited the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406758	25902146	MB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Edited the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406758	25902146	MB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Edited the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406758	25902146	MB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Edited the manuscript	Edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
4406758	25902146	MLC	PLoS5	Performed the experiments|Edited the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4406758	25902146	MLC	PLoS5	Performed the experiments|Edited the manuscript	Edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5364626	28335732	AF	2	performed eqtl analyses	performed eqtl analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5364626	28335732	AKK	2	performed the majority of laboratory studies and data analyses|wrote the manuscript	performed the majority of laboratory studies and data analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5364626	28335732	AKK	2	performed the majority of laboratory studies and data analyses|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5364626	28335732	All authors	2	commented on the content of the paper	commented on the content of the paper	-	-	NO
5364626	28335732	CM	2	contributed to study design, data interpretation and performed protein synthesis assays	contributed to study design, data interpretation and performed protein synthesis assays	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Methodology|Resources	YES
5364626	28335732	IPH	2	wrote the manuscript|supervised the laboratory work	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5364626	28335732	IPH	2	wrote the manuscript|supervised the laboratory work	supervised the laboratory work	Performed the experiments	Investigation|Supervision	YES
5364626	28335732	IS	2	wrote the manuscript|supervised the laboratory work	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5364626	28335732	IS	2	wrote the manuscript|supervised the laboratory work	supervised the laboratory work	Performed the experiments	Investigation|Supervision	YES
5583599	28912795	All authors	PLoS52	contributed to writing and editing the manuscript	contributed to writing and editing the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5583599	28912795	GZ	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5583599	28912795	JL	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5583599	28912795	YL	PLoS52	performed the experiments and wrote the main manuscript	performed the experiments and wrote the main manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
2898672	20529272	AMS	2	participated in the design and realization of the study and drafted the manuscript	participated in the design and realization of the study and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
2898672	20529272	HP	2	coordinated the study	coordinated the study	-	Project administration	YES
2898672	20529272	NBK	2	helped to draft the manuscript and a project report	helped to draft the manuscript and a project report	Wrote the paper	Writing - Original Draft	YES
5712507	29199391	All	2	authors participated in the construction of the survey, data collection, consistency checks, discussion of results, and preparation of the manuscript	authors participated in the construction of the survey, data collection, consistency checks, discussion of results, and preparation of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5712507	29199391	ES	2	implemented the web-based form and contributed to data curation	implemented the web-based form and contributed to data curation	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Investigation|Software	YES
5712507	29199391	IDTF	2	authors participated in the construction of the survey, data collection, consistency checks, discussion of results, and preparation of the manuscript	authors participated in the construction of the survey, data collection, consistency checks, discussion of results, and preparation of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5712507	29199391	KSG	2	contributed to the implementation of the web-based form, data curation and consistency checks, performed the data analysis, and drafted the manuscript	contributed to the implementation of the web-based form, data curation and consistency checks, performed the data analysis, and drafted the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Data curation|Formal analysis|Investigation|Resources|Software|Writing - Original Draft|Writing - Review & Editing	YES
5712507	29199391	PS	2	prepared material for consistency checks	prepared material for consistency checks	Performed the experiments	Investigation	YES
6287574	30568795	CT	2	scan and histopathology	scan and histopathology	Performed the experiments	Investigation	YES
6287574	30568795	Kamal Pandit	2	wrote the report	wrote the report	Wrote the paper	Writing - Original Draft	YES
6287574	30568795	Shekhar Bhatta-He	2	searched the relevant articles for references and wrote some portion of discussion	searched the relevant articles for references and wrote some portion of discussion	Wrote the paper	Writing - Original Draft	YES
6287574	30568795	Suman Khanal-He	2	took the pictures of the colonoscopy	took the pictures of the colonoscopy	Performed the experiments	Investigation|Visualization	YES
4251638	25485147	Addisu Gize	2	conceived the study and participated in the design and data analysis	conceived the study and participated in the design and data analysis	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
4251638	25485147	Beyene Moges	2	conceived the study and participated in the design and data analysis	conceived the study and participated in the design and data analysis	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
4251638	25485147	Biniam Mathewos	2	conceived the study and participated in the design and data analysis	conceived the study and participated in the design and data analysis	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
4251638	25485147	Lealem Gedefaw	2	critically reviewed the paper	critically reviewed the paper	Wrote the paper	Writing - Review & Editing	YES
4251638	25485147	Meseret Workineh	2	involved in data acquisition and laboratory work and drafted the paper	involved in data acquisition and laboratory work and drafted the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5583600	28912792	F-ML	PLoS52	conceived and designed the experiments|wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5583600	28912792	F-ML	PLoS52	conceived and designed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5583600	28912792	JH	PLoS52	conceived and designed the experiments|conducted experiments|wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5583600	28912792	JH	PLoS52	conceived and designed the experiments|conducted experiments|wrote the manuscript	conducted experiments	Performed the experiments	Investigation	YES
5583600	28912792	JH	PLoS52	conceived and designed the experiments|conducted experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5583600	28912792	KS	PLoS52	contributed to the analysis and interpretation of the data	contributed to the analysis and interpretation of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5583600	28912792	NT	PLoS52	conceived and designed the experiments|wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5583600	28912792	NT	PLoS52	conceived and designed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5583600	28912792	R-PY	PLoS52	contributed to the analysis and interpretation of the data	contributed to the analysis and interpretation of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5583600	28912792	TW	PLoS52	conducted experiments	conducted experiments	Performed the experiments	Investigation	YES
5583600	28912792	Y-LD	PLoS52	contributed to the analysis and interpretation of the data	contributed to the analysis and interpretation of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5583600	28912792	YJ	PLoS52	conceived and designed the experiments|conducted experiments|wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5583600	28912792	YJ	PLoS52	conceived and designed the experiments|conducted experiments|wrote the manuscript	conducted experiments	Performed the experiments	Investigation	YES
5583600	28912792	YJ	PLoS52	conceived and designed the experiments|conducted experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5583600	28912792	all authors	PLoS52	contributed to the discussion and approved the final manuscript	contributed to the discussion and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4406759	25901745	E. Temereva	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406759	25901745	E. Temereva	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406759	25901745	E. Temereva	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406759	25901745	E. Temereva	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406759	25901745	E. Tsitrin	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4406759	25901745	E. Tsitrin	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2901226	20529367	LJ	2	participated in the conceptualization of the study, performed the research, wrote the initial draft and participated in subsequent rewrites of the manuscript	participated in the conceptualization of the study, performed the research, wrote the initial draft and participated in subsequent rewrites of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
2901226	20529367	RBS	2	participated in the conceptualization of the study and participated in subsequent rewrites of the manuscript	participated in the conceptualization of the study and participated in subsequent rewrites of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
5716967	29209862	AAL	2	contributed to the data interpretation, review, and final approval of the paper	contributed to the data interpretation, review, and final approval of the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5716967	29209862	ADW	2	contributed to the tracer development, data acquisition, review, and final approval of the paper	contributed to the tracer development, data acquisition, review, and final approval of the paper	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5716967	29209862	BNMB	2	contributed to the data acquisition, review, and final approval of the paper	contributed to the data acquisition, review, and final approval of the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5716967	29209862	MY	2	contributed to the data interpretation and review and final approval of the paper	contributed to the data interpretation and review and final approval of the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5716967	29209862	RB	2	contributed to the project design, data analysis and interpretation, drafting, and final approval of the paper	contributed to the project design, data analysis and interpretation, drafting, and final approval of the paper	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Original Draft	YES
5716967	29209862	SMA	2	contributed to the data analysis and interpretation, drafting, and final approval of the paper	contributed to the data analysis and interpretation, drafting, and final approval of the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5716967	29209862	SSVG	2	contributed to the project design, data analysis and interpretation, drafting, and final approval of the paper	contributed to the project design, data analysis and interpretation, drafting, and final approval of the paper	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Original Draft	YES
4515515	26247035	Hui Zhao	2	contributed equally to this work	contributed equally to this work	-	-	NO
4515515	26247035	Jian Qiu	2	contributed equally to this work	contributed equally to this work	-	-	NO
4515515	26247035	Lin Xu	2	contributed equally to this work	contributed equally to this work	-	-	NO
5364632	28335741	BC	2	participated in the design and coordination and helped to draft the manuscript	participated in the design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Project administration|Writing - Original Draft	YES
5364632	28335741	DL	2	conceived and designed the study, participated in coordination and contributed to draft manuscript writing and revisions	conceived and designed the study, participated in coordination and contributed to draft manuscript writing and revisions	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft|Writing - Review & Editing	YES
5364632	28335741	JG	2	worked at the illumina sequencing data generation and data preprocessing|carried out the qrt-pcr and detection of snps in mirnas	worked at the illumina sequencing data generation and data preprocessing	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5364632	28335741	JG	2	worked at the illumina sequencing data generation and data preprocessing|carried out the qrt-pcr and detection of snps in mirnas	carried out the qrt-pcr and detection of snps in mirnas	Performed the experiments	Investigation	YES
5364632	28335741	NW	2	worked at the illumina sequencing data generation and data preprocessing|analyzed and interpreted the data, and drafted the manuscript|carried out the qrt-pcr and detection of snps in mirnas	worked at the illumina sequencing data generation and data preprocessing	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5364632	28335741	NW	2	worked at the illumina sequencing data generation and data preprocessing|analyzed and interpreted the data, and drafted the manuscript|carried out the qrt-pcr and detection of snps in mirnas	analyzed and interpreted the data, and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5364632	28335741	NW	2	worked at the illumina sequencing data generation and data preprocessing|analyzed and interpreted the data, and drafted the manuscript|carried out the qrt-pcr and detection of snps in mirnas	carried out the qrt-pcr and detection of snps in mirnas	Performed the experiments	Investigation	YES
5364632	28335741	QZ	2	conceived and designed the study, participated in coordination and contributed to draft manuscript writing and revisions|participated in the design and coordination and helped to draft the manuscript	conceived and designed the study, participated in coordination and contributed to draft manuscript writing and revisions	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft|Writing - Review & Editing	YES
5364632	28335741	QZ	2	conceived and designed the study, participated in coordination and contributed to draft manuscript writing and revisions|participated in the design and coordination and helped to draft the manuscript	participated in the design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Project administration|Writing - Original Draft	YES
5364632	28335741	ZX	2	participated in the design and coordination and helped to draft the manuscript	participated in the design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Project administration|Writing - Original Draft	YES
2914675	20615219	AM	2	is the invited author and conceived and wrote the original paper	is the invited author and conceived and wrote the original paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
2914675	20615219	RH	2	edited, contributed advice and further references	edited, contributed advice and further references	Wrote the paper	Writing - Review & Editing	YES
5583601	28912793	BU	2	carried out the major work and prepared manuscript and contributed to the refinement of the manuscript	carried out the major work and prepared manuscript and contributed to the refinement of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5583601	28912793	BV	2	carried out the major work and prepared manuscript and contributed to the refinement of the manuscript	carried out the major work and prepared manuscript and contributed to the refinement of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5583601	28912793	MSM	2	designed all experiments, developed the structure and arguments for the paper, made critical revisions, and approved the final version	designed all experiments, developed the structure and arguments for the paper, made critical revisions, and approved the final version	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5583601	28912793	PKS	2	helped in the collection and phenotypic screening of rice landraces for neck blast resistance at the north-east region	helped in the collection and phenotypic screening of rice landraces for neck blast resistance at the north-east region	Performed the experiments	Investigation	YES
5583601	28912793	PS	2	reviewed and approved the final manuscript	reviewed and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5583601	28912793	SK	2	helped in the collection and phenotypic screening of rice landraces for neck blast resistance at the north-east region	helped in the collection and phenotypic screening of rice landraces for neck blast resistance at the north-east region	Performed the experiments	Investigation	YES
5583601	28912793	SKS	2	helped in the collection and phenotypic screening of rice landraces for neck blast resistance at the north-east region	helped in the collection and phenotypic screening of rice landraces for neck blast resistance at the north-east region	Performed the experiments	Investigation	YES
5583601	28912793	SRD	2	helped in data collection of agro-morphological traits	helped in data collection of agro-morphological traits	Performed the experiments	Investigation	YES
5583601	28912793	VPB	2	helped in the collection and phenotypic screening of rice landraces for neck blast resistance at the north-east region	helped in the collection and phenotypic screening of rice landraces for neck blast resistance at the north-east region	Performed the experiments	Investigation	YES
2914676	20618947	The author	2	is solely responsible for this manuscript	is solely responsible for this manuscript	-	-	NO
6423304	30962923	all authors	2	made substantial contributions to this study	made substantial contributions to this study	-	-	NO
5364699	28340563	BL	2	participated in data analysis and the manuscript preparation	participated in data analysis and the manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5364699	28340563	GK	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5364699	28340563	HG	2	participated in data analysis and the manuscript preparation	participated in data analysis and the manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5364699	28340563	JY	2	analyzed the data and prepared the manuscript	analyzed the data and prepared the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5364699	28340563	LW	2	participated in data analysis and the manuscript preparation	participated in data analysis and the manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5364699	28340563	XZ	2	participated in data analysis and the manuscript preparation	participated in data analysis and the manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5725400	29230607	AC	2	designed the study|carried out the phantom preparations, acquisitions and reconstructions	designed the study	Conceived and designed the experiments	Methodology	YES
5725400	29230607	AC	2	designed the study|carried out the phantom preparations, acquisitions and reconstructions	carried out the phantom preparations, acquisitions and reconstructions	Performed the experiments	Investigation	YES
5725400	29230607	JOD	2	designed the study|carried out the phantom preparations, acquisitions and reconstructions|analysed and interpreted the resulting data|drafted the manuscript, which was revised by all authors	designed the study	Conceived and designed the experiments	Methodology	YES
5725400	29230607	JOD	2	designed the study|carried out the phantom preparations, acquisitions and reconstructions|analysed and interpreted the resulting data|drafted the manuscript, which was revised by all authors	carried out the phantom preparations, acquisitions and reconstructions	Performed the experiments	Investigation	YES
5725400	29230607	JOD	2	designed the study|carried out the phantom preparations, acquisitions and reconstructions|analysed and interpreted the resulting data|drafted the manuscript, which was revised by all authors	analysed and interpreted the resulting data	Analyzed the data	Formal analysis	YES
5725400	29230607	JOD	2	designed the study|carried out the phantom preparations, acquisitions and reconstructions|analysed and interpreted the resulting data|drafted the manuscript, which was revised by all authors	drafted the manuscript, which was revised by all authors	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5725400	29230607	MSN	2	designed the study|carried out the phantom preparations, acquisitions and reconstructions	designed the study	Conceived and designed the experiments	Methodology	YES
5725400	29230607	MSN	2	designed the study|carried out the phantom preparations, acquisitions and reconstructions	carried out the phantom preparations, acquisitions and reconstructions	Performed the experiments	Investigation	YES
5725400	29230607	PKM	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5725400	29230607	PS	2	analysed and interpreted the resulting data	analysed and interpreted the resulting data	Analyzed the data	Formal analysis	YES
5725400	29230607	ZC	2	analysed and interpreted the resulting data|drafted the manuscript, which was revised by all authors	analysed and interpreted the resulting data	Analyzed the data	Formal analysis	YES
5725400	29230607	ZC	2	analysed and interpreted the resulting data|drafted the manuscript, which was revised by all authors	drafted the manuscript, which was revised by all authors	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4406761	25902072	AI	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4406761	25902072	AI	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406761	25902072	AL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406761	25902072	AL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406761	25902072	AL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406761	25902072	AL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406761	25902072	AP	PLoS5	Contributed reagents/materials/analysis tools|Provided support in the form of salary, but did not have any additional role in the study design, data collection and analysis, decision to publish, or preparation of the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406761	25902072	AP	PLoS5	Contributed reagents/materials/analysis tools|Provided support in the form of salary, but did not have any additional role in the study design, data collection and analysis, decision to publish, or preparation of the manuscript	Provided support in the form of salary, but did not have any additional role in the study design, data collection and analysis, decision to publish, or preparation of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
4406761	25902072	EE	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406761	25902072	EE	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406761	25902072	EE	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406761	25902072	EM	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4406761	25902072	GA	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406761	25902072	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406761	25902072	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406761	25902072	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406761	25902072	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406761	25902072	NN	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406761	25902072	PB	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406761	25902072	PB	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5515015	28453241	All authors	2	reviewed this manuscript, provided feedback, and approved of the manuscript in its final form	reviewed this manuscript, provided feedback, and approved of the manuscript in its final form	Wrote the paper	Writing - Review & Editing	YES
5515015	28453241	BK	2	oversaw the collection of clinical data	oversaw the collection of clinical data	Performed the experiments	Investigation|Supervision	YES
5515015	28453241	JA	2	contributed to the design of the analysis and assisted in the interpretation of results	contributed to the design of the analysis and assisted in the interpretation of results	Conceived and designed the experiments|Analyzed the data	Formal analysis	YES
5515015	28453241	MC	2	contributed to the design of the analysis and assisted in the interpretation of results	contributed to the design of the analysis and assisted in the interpretation of results	Conceived and designed the experiments|Analyzed the data	Formal analysis	YES
5515015	28453241	RN	2	contributed to the design of the analysis and assisted in the interpretation of results	contributed to the design of the analysis and assisted in the interpretation of results	Conceived and designed the experiments|Analyzed the data	Formal analysis	YES
5515015	28453241	SA	2	oversaw the collection of clinical data	oversaw the collection of clinical data	Performed the experiments	Investigation|Supervision	YES
5515015	28453241	SB	2	contributed to the design of the analysis and assisted in the interpretation of results	contributed to the design of the analysis and assisted in the interpretation of results	Conceived and designed the experiments|Analyzed the data	Formal analysis	YES
5515015	28453241	SRS	2	contributed to the design of the analysis and assisted in the interpretation of results	contributed to the design of the analysis and assisted in the interpretation of results	Conceived and designed the experiments|Analyzed the data	Formal analysis	YES
5515015	28453241	SS	2	contributed to the design of the analysis and assisted in the interpretation of results	contributed to the design of the analysis and assisted in the interpretation of results	Conceived and designed the experiments|Analyzed the data	Formal analysis	YES
5515015	28453241	TC	2	designed this analysis and authored the first draft of the manuscript	designed this analysis and authored the first draft of the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
5515015	28453241	WB	2	contributed to the design of the analysis and assisted in the interpretation of results	contributed to the design of the analysis and assisted in the interpretation of results	Conceived and designed the experiments|Analyzed the data	Formal analysis	YES
5583604	28912791	AR	2	performed the isotope analyses	performed the isotope analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5583604	28912791	FL	2	performed the isotope analyses|performed the statistical analyses	performed the isotope analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5583604	28912791	FL	2	performed the isotope analyses|performed the statistical analyses	performed the statistical analyses	Analyzed the data	Formal analysis	YES
5583604	28912791	HJ	2	designed the experiment|performed the field work|performed the statistical analyses|wrote the first draft of the manuscript	designed the experiment	Conceived and designed the experiments	Methodology	YES
5583604	28912791	HJ	2	designed the experiment|performed the field work|performed the statistical analyses|wrote the first draft of the manuscript	performed the field work	Performed the experiments	Investigation	YES
5583604	28912791	HJ	2	designed the experiment|performed the field work|performed the statistical analyses|wrote the first draft of the manuscript	performed the statistical analyses	Analyzed the data	Formal analysis	YES
5583604	28912791	HJ	2	designed the experiment|performed the field work|performed the statistical analyses|wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
5583604	28912791	M-AS	2	designed the experiment|wrote the first draft of the manuscript	designed the experiment	Conceived and designed the experiments	Methodology	YES
5583604	28912791	M-AS	2	designed the experiment|wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
5583604	28912791	MW	2	performed the molecular analyses|performed the statistical analyses	performed the molecular analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5583604	28912791	MW	2	performed the molecular analyses|performed the statistical analyses	performed the statistical analyses	Analyzed the data	Formal analysis	YES
5583604	28912791	P-EC	2	performed the isotope analyses	performed the isotope analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5583604	28912791	RB	2	designed the experiment|performed the field work	designed the experiment	Conceived and designed the experiments	Methodology	YES
5583604	28912791	RB	2	designed the experiment|performed the field work	performed the field work	Performed the experiments	Investigation	YES
5583604	28912791	all authors	2	read and approved the final draft	read and approved the final draft	Wrote the paper	Writing - Original Draft	YES
5364715	28335735	AI	2	designed the study|conducted data elaboration|wrote the first draft the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5364715	28335735	AI	2	designed the study|conducted data elaboration|wrote the first draft the manuscript	conducted data elaboration	-	-	NO
5364715	28335735	AI	2	designed the study|conducted data elaboration|wrote the first draft the manuscript	wrote the first draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5364715	28335735	AM	2	contributed to clinical interpretation of the data	contributed to clinical interpretation of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5364715	28335735	All authors	2	contributed to the literary review|significantly contributed to the revision of the manuscript	contributed to the literary review	-	-	NO
5364715	28335735	All authors	2	contributed to the literary review|significantly contributed to the revision of the manuscript	significantly contributed to the revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5364715	28335735	DM	2	contributed to clinical interpretation of the data	contributed to clinical interpretation of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5364715	28335735	FDA	2	conducted data elaboration	conducted data elaboration	-	-	NO
5364715	28335735	FM	2	contributed to clinical interpretation of the data	contributed to clinical interpretation of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5364715	28335735	LGP	2	contributed to clinical interpretation of the data	contributed to clinical interpretation of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5364715	28335735	MDG	2	contributed to clinical interpretation of the data	contributed to clinical interpretation of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5364715	28335735	MF	2	conducted data elaboration	conducted data elaboration	-	-	NO
5364715	28335735	ML	2	contributed to clinical interpretation of the data	contributed to clinical interpretation of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5364715	28335735	RP	2	designed the study|conducted data elaboration|wrote the first draft the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5364715	28335735	RP	2	designed the study|conducted data elaboration|wrote the first draft the manuscript	conducted data elaboration	-	-	NO
5364715	28335735	RP	2	designed the study|conducted data elaboration|wrote the first draft the manuscript	wrote the first draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5364715	28335735	SF	2	contributed to clinical interpretation of the data	contributed to clinical interpretation of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
4406762	25902044	BCC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406762	25902044	BCC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406762	25902044	JEL	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406762	25902044	JER	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406762	25902044	JER	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4406762	25902044	JER	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4406762	25902044	KHB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406762	25902044	KHB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406762	25902044	KHB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406762	25902044	KJL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406762	25902044	KJL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4406762	25902044	KJL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406762	25902044	LL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406762	25902044	LL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406762	25902044	LL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406762	25902044	LL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5732128	29247300	JG	2	contributed to the simind ml-em framework and to the consistency of the pinhole reconstruction implementation and revised the manuscript	contributed to the simind ml-em framework and to the consistency of the pinhole reconstruction implementation and revised the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5732128	29247300	MP	2	implemented the pinhole back-projector, performed the phantom experiments, evaluated the results, and prepared the manuscript	implemented the pinhole back-projector, performed the phantom experiments, evaluated the results, and prepared the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5732128	29247300	SIMIND	2	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
4312629	25664185	All authors	2	were involved in the development of the primary paper and interpretation of data, have read and approved the final version, and have met the criteria for authorship as established by the icmje	were involved in the development of the primary paper and interpretation of data, have read and approved the final version, and have met the criteria for authorship as established by the icmje	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4312629	25664185	Andre Nell	2	all participated in recruiting significant numbers of patients to the trials and reported data for those patients	all participated in recruiting significant numbers of patients to the trials and reported data for those patients	Performed the experiments	Investigation	YES
4312629	25664185	Catherine Orrell	2	all participated in recruiting significant numbers of patients to the trials and reported data for those patients	all participated in recruiting significant numbers of patients to the trials and reported data for those patients	Performed the experiments	Investigation	YES
4312629	25664185	Franco Felizarta	2	all participated in recruiting significant numbers of patients to the trials and reported data for those patients	all participated in recruiting significant numbers of patients to the trials and reported data for those patients	Performed the experiments	Investigation	YES
4312629	25664185	Frank L. Tomaka	2	all had a significant involvement in the data analyses	all had a significant involvement in the data analyses	Analyzed the data	Formal analysis	YES
4312629	25664185	Van Solingen-Ristea	2	all had a significant involvement in the data analyses	all had a significant involvement in the data analyses	Analyzed the data	Formal analysis	YES
2949619	20825676	Both authors	2	contributed equally and have read and approved this manuscript	contributed equally and have read and approved this manuscript	-	-	NO
5583605	28912785	GB	2	contributed reagents|contributed to conceive the project and revise the paper	contributed reagents	Contributed reagents/materials/analysis tools	Resources	YES
5583605	28912785	GB	2	contributed reagents|contributed to conceive the project and revise the paper	contributed to conceive the project and revise the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5583605	28912785	GZ	2	contributed to conceive the project and revise the paper	contributed to conceive the project and revise the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5583605	28912785	HA	2	analyzed the data and wrote the paper|contributed to conceive the project and revise the paper	analyzed the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5583605	28912785	HA	2	analyzed the data and wrote the paper|contributed to conceive the project and revise the paper	contributed to conceive the project and revise the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5583605	28912785	Ion Proton	2	sequencing and analysis tools	sequencing and analysis tools	Performed the experiments	Investigation	YES
5583605	28912785	MB	2	provided seeds of the genotypes|contributed to conceive the project and revise the paper	provided seeds of the genotypes	Performed the experiments	Investigation	YES
5583605	28912785	MB	2	provided seeds of the genotypes|contributed to conceive the project and revise the paper	contributed to conceive the project and revise the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5583605	28912785	SP	2	provided seeds of the genotypes|contributed to conceive the project and revise the paper	provided seeds of the genotypes	Performed the experiments	Investigation	YES
5583605	28912785	SP	2	provided seeds of the genotypes|contributed to conceive the project and revise the paper	contributed to conceive the project and revise the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5583605	28912785	VM	2	provided seeds of the genotypes|contributed to conceive the project and revise the paper	provided seeds of the genotypes	Performed the experiments	Investigation	YES
5583605	28912785	VM	2	provided seeds of the genotypes|contributed to conceive the project and revise the paper	contributed to conceive the project and revise the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
2984418	21040525	AM	2	conceptualized, drafted and revised the manuscript and contributed equally to its development	conceptualized, drafted and revised the manuscript and contributed equally to its development	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
2984418	21040525	CB	2	conceptualized, drafted and revised the manuscript and contributed equally to its development	conceptualized, drafted and revised the manuscript and contributed equally to its development	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
2984418	21040525	JS	2	conceptualized, drafted and revised the manuscript and contributed equally to its development	conceptualized, drafted and revised the manuscript and contributed equally to its development	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
4406763	25902140	BPK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406763	25902140	BPK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406763	25902140	BPK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406763	25902140	BWZ	PLoS5	Recruited and performed clinical follow-up on human subjects	Recruited and performed clinical follow-up on human subjects	Performed the experiments	Investigation	YES
4406763	25902140	DMBP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406763	25902140	DMBP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406763	25902140	DMBP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406763	25902140	DMBP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406763	25902140	DMJ	PLoS5	Recruited and performed clinical follow-up on human subjects	Recruited and performed clinical follow-up on human subjects	Performed the experiments	Investigation	YES
4406763	25902140	FB	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4406763	25902140	KRF	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406763	25902140	KRF	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406763	25902140	LMR	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4406763	25902140	MEB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406763	25902140	MEB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406763	25902140	MEB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406763	25902140	MPT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406763	25902140	MPT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406763	25902140	MPT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406763	25902140	MPT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406763	25902140	MPT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406763	25902140	SDR	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4406763	25902140	SDR	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406763	25902140	SMS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406763	25902140	SMS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406763	25902140	SMS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5366136	28340555	All authors	2	wrote, read, and approved the final version of the manuscript	wrote, read, and approved the final version of the manuscript	Wrote the paper	Writing - Original Draft	YES
5366136	28340555	DWO	2	assisted with the supervised the feeding trials and biopsy experiments with the	assisted with the supervised the feeding trials and biopsy experiments with the	Performed the experiments	Investigation|Supervision	YES
5366136	28340555	GM	2	assisted with the analysed all the data and wrote the first draft of the manuscript with|contributed substantially to bioinformatics analyses	assisted with the analysed all the data and wrote the first draft of the manuscript with	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5366136	28340555	GM	2	assisted with the analysed all the data and wrote the first draft of the manuscript with|contributed substantially to bioinformatics analyses	contributed substantially to bioinformatics analyses	Analyzed the data	Formal analysis	YES
5366136	28340555	JKH	2	assisted with the supervised the feeding trials and biopsy experiments with the	assisted with the supervised the feeding trials and biopsy experiments with the	Performed the experiments	Investigation|Supervision	YES
5366136	28340555	PL	2	supervised the feeding trials and biopsy experiments with the|provided rfi measurements of cattle in the experiment	supervised the feeding trials and biopsy experiments with the	Performed the experiments	Investigation|Supervision	YES
5366136	28340555	PL	2	supervised the feeding trials and biopsy experiments with the|provided rfi measurements of cattle in the experiment	provided rfi measurements of cattle in the experiment	Performed the experiments	Investigation	YES
5366136	28340555	PLund	2	supervised the feeding trials and biopsy experiments with the	supervised the feeding trials and biopsy experiments with the	Performed the experiments	Investigation|Supervision	YES
5366136	28340555	RFI	2	supervised sms in the laboratory work and bioinformatics/systems biology analyses	supervised sms in the laboratory work and bioinformatics/systems biology analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Supervision	YES
5366136	28340555	SMS	2	processed liver tissue for the rna isolation as well as quality control of rna samples before rna sequencing|analysed all the data and wrote the first draft of the manuscript with	processed liver tissue for the rna isolation as well as quality control of rna samples before rna sequencing	Performed the experiments|Analyzed the data	Data curation|Investigation|Validation	YES
5366136	28340555	SMS	2	processed liver tissue for the rna isolation as well as quality control of rna samples before rna sequencing|analysed all the data and wrote the first draft of the manuscript with	analysed all the data and wrote the first draft of the manuscript with	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5754277	29302810	IM	2	participated in the design of the study, method development, and revised the manuscript critically	participated in the design of the study, method development, and revised the manuscript critically	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5754277	29302810	JH	2	participated in the design of the study, method development, and revised the manuscript critically	participated in the design of the study, method development, and revised the manuscript critically	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5754277	29302810	JHL	2	participated in the design of the study, method development, and revised the manuscript critically	participated in the design of the study, method development, and revised the manuscript critically	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5754277	29302810	JS	2	supervised the selection of patients and the analysis and revised the manuscript critically	supervised the selection of patients and the analysis and revised the manuscript critically	Wrote the paper	Supervision|Writing - Review & Editing	YES
5754277	29302810	MB	2	participated in the method development, helped to draft the manuscript and revised it critically	participated in the method development, helped to draft the manuscript and revised it critically	Performed the experiments|Wrote the paper	Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5754277	29302810	PB	2	conceived of the study, participated in its design, method development and coordination, and drafted the manuscript	conceived of the study, participated in its design, method development and coordination, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
5754277	29302810	PG	2	supervised the selection of patients and the analysis and revised the manuscript critically	supervised the selection of patients and the analysis and revised the manuscript critically	Wrote the paper	Supervision|Writing - Review & Editing	YES
5754277	29302810	TM	2	participated in the study design, method development, created the program script, and co-drafted the manuscript	participated in the study design, method development, created the program script, and co-drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Methodology|Software|Writing - Original Draft	YES
5584390	28912790	AR	2	prepared tables, figures, and wrote the manuscript|conducted the qtl evaluations	prepared tables, figures, and wrote the manuscript	Wrote the paper	Visualization|Writing - Original Draft	YES
5584390	28912790	AR	2	prepared tables, figures, and wrote the manuscript|conducted the qtl evaluations	conducted the qtl evaluations	Performed the experiments	Investigation	YES
5584390	28912790	All authors	2	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5584390	28912790	BD	2	developed the study and designed the experimental trials|conducted the qtl evaluations	developed the study and designed the experimental trials	Conceived and designed the experiments	Methodology	YES
5584390	28912790	BD	2	developed the study and designed the experimental trials|conducted the qtl evaluations	conducted the qtl evaluations	Performed the experiments	Investigation	YES
5584390	28912790	CG	2	implemented the evaluations	implemented the evaluations	Performed the experiments	Investigation	YES
5584390	28912790	CRG	2	developed the study and designed the experimental trials	developed the study and designed the experimental trials	Conceived and designed the experiments	Methodology	YES
5584390	28912790	DLS	2	developed the study and designed the experimental trials|conducted the data analyses|are the corresponding authors on this manuscript and the pis of the project under which this study was carried out	developed the study and designed the experimental trials	Conceived and designed the experiments	Methodology	YES
5584390	28912790	DLS	2	developed the study and designed the experimental trials|conducted the data analyses|are the corresponding authors on this manuscript and the pis of the project under which this study was carried out	conducted the data analyses	Analyzed the data	Formal analysis	YES
5584390	28912790	DLS	2	developed the study and designed the experimental trials|conducted the data analyses|are the corresponding authors on this manuscript and the pis of the project under which this study was carried out	are the corresponding authors on this manuscript and the pis of the project under which this study was carried out	Performed the experiments	Investigation	YES
5584390	28912790	JW	2	implemented the evaluations|conducted the data analyses|prepared tables, figures, and wrote the manuscript	implemented the evaluations	Performed the experiments	Investigation	YES
5584390	28912790	JW	2	implemented the evaluations|conducted the data analyses|prepared tables, figures, and wrote the manuscript	conducted the data analyses	Analyzed the data	Formal analysis	YES
5584390	28912790	JW	2	implemented the evaluations|conducted the data analyses|prepared tables, figures, and wrote the manuscript	prepared tables, figures, and wrote the manuscript	Wrote the paper	Visualization|Writing - Original Draft	YES
5584390	28912790	MK	2	developed the study and designed the experimental trials|conducted the qtl evaluations|are the corresponding authors on this manuscript and the pis of the project under which this study was carried out	developed the study and designed the experimental trials	Conceived and designed the experiments	Methodology	YES
5584390	28912790	MK	2	developed the study and designed the experimental trials|conducted the qtl evaluations|are the corresponding authors on this manuscript and the pis of the project under which this study was carried out	conducted the qtl evaluations	Performed the experiments	Investigation	YES
5584390	28912790	MK	2	developed the study and designed the experimental trials|conducted the qtl evaluations|are the corresponding authors on this manuscript and the pis of the project under which this study was carried out	are the corresponding authors on this manuscript and the pis of the project under which this study was carried out	Performed the experiments	Investigation	YES
5584390	28912790	MM	2	implemented the evaluations|conducted the data analyses|prepared tables, figures, and wrote the manuscript	implemented the evaluations	Performed the experiments	Investigation	YES
5584390	28912790	MM	2	implemented the evaluations|conducted the data analyses|prepared tables, figures, and wrote the manuscript	conducted the data analyses	Analyzed the data	Formal analysis	YES
5584390	28912790	MM	2	implemented the evaluations|conducted the data analyses|prepared tables, figures, and wrote the manuscript	prepared tables, figures, and wrote the manuscript	Wrote the paper	Visualization|Writing - Original Draft	YES
4325476	25709840	Asres Berhan	2	mainly worked on literature search, data extraction, and analysis	mainly worked on literature search, data extraction, and analysis	Performed the experiments|Analyzed the data	Data curation|Formal analysis	YES
4325476	25709840	Yifru Berhan	2	conceived the idea and was involved in literature search, data extraction, analysis, and writing	conceived the idea and was involved in literature search, data extraction, analysis, and writing	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Data curation|Formal analysis	YES
4406764	25902358	QM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406764	25902358	QM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406764	25902358	QM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406764	25902358	QM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406764	25902358	QM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406764	25902358	WZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406764	25902358	WZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406764	25902358	WZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406764	25902358	WZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406764	25902358	WZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5368935	28351369	RVB	5	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5762619	29322344	JT	2	assisted with the data acquisition and discussion	assisted with the data acquisition and discussion	Performed the experiments	Investigation	YES
5762619	29322344	MG	2	assisted with the data acquisition and discussion	assisted with the data acquisition and discussion	Performed the experiments	Investigation	YES
5762619	29322344	PE	2	assisted with the data acquisition and discussion	assisted with the data acquisition and discussion	Performed the experiments	Investigation	YES
5762619	29322344	WZ	2	assisted with the count rate determinations in clinical studies and was involved in the discussion	assisted with the count rate determinations in clinical studies and was involved in the discussion	-	-	NO
5585147	28919906	GC	2	performed the experiments, analyzed the data, and wrote the manuscript	performed the experiments, analyzed the data, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5585147	28919906	MG	2	conceived, designed and supervised the study	conceived, designed and supervised the study	Conceived and designed the experiments	Conceptualization|Methodology|Supervision	YES
3037871	21276254	KS	2	contributed equally to the research, analysis and writing of this paper	contributed equally to the research, analysis and writing of this paper	Wrote the paper	Writing - Original Draft	YES
3037871	21276254	MAO	2	contributed equally to the research, analysis and writing of this paper	contributed equally to the research, analysis and writing of this paper	Wrote the paper	Writing - Original Draft	YES
4406848	25901353	CJT	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Contributed to the writing of the manuscript|Design algorithm	Analyzed the data	Analyzed the data	Formal analysis	YES
4406848	25901353	CJT	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Contributed to the writing of the manuscript|Design algorithm	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406848	25901353	CJT	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Contributed to the writing of the manuscript|Design algorithm	Contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
4406848	25901353	CJT	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Contributed to the writing of the manuscript|Design algorithm	Design algorithm	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
4406848	25901353	DNA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Gene knock-out experiment	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406848	25901353	DNA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Gene knock-out experiment	Performed the experiments	Performed the experiments	Investigation	YES
4406848	25901353	DNA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Gene knock-out experiment	Analyzed the data	Analyzed the data	Formal analysis	YES
4406848	25901353	DNA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Gene knock-out experiment	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406848	25901353	DNA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Gene knock-out experiment	Gene knock-out experiment	-	-	NO
4406848	25901353	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406848	25901353	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4406848	25901353	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4406848	25901353	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406848	25901353	JMC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed to the writing of the manuscript|Neural dataset	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406848	25901353	JMC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed to the writing of the manuscript|Neural dataset	Performed the experiments	Performed the experiments	Investigation	YES
4406848	25901353	JMC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed to the writing of the manuscript|Neural dataset	Analyzed the data	Analyzed the data	Formal analysis	YES
4406848	25901353	JMC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed to the writing of the manuscript|Neural dataset	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406848	25901353	JMC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed to the writing of the manuscript|Neural dataset	Contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
4406848	25901353	JMC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed to the writing of the manuscript|Neural dataset	Neural dataset	-	-	NO
4406848	25901353	JWG	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406848	25901353	JWG	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4406848	25901353	MMM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Gene knock-out experiment	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406848	25901353	MMM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Gene knock-out experiment	Performed the experiments	Performed the experiments	Investigation	YES
4406848	25901353	MMM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Gene knock-out experiment	Analyzed the data	Analyzed the data	Formal analysis	YES
4406848	25901353	MMM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Gene knock-out experiment	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406848	25901353	MMM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Gene knock-out experiment	Gene knock-out experiment	-	-	NO
4406848	25901353	YHC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Contributed to the writing of the manuscript|Design algorithm	Analyzed the data	Analyzed the data	Formal analysis	YES
4406848	25901353	YHC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Contributed to the writing of the manuscript|Design algorithm	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406848	25901353	YHC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Contributed to the writing of the manuscript|Design algorithm	Contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
4406848	25901353	YHC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Contributed to the writing of the manuscript|Design algorithm	Design algorithm	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
5792384	29388075	GEF	2	contributed to the coordination of the human study and obtained ethics approval	contributed to the coordination of the human study and obtained ethics approval	-	Project administration	YES
5792384	29388075	JO	2	designed the study, supervised the project, and drafted and edited the manuscript	designed the study, supervised the project, and drafted and edited the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
5792384	29388075	KY	2	contributed to the coordination of the data analysis and supervised the project	contributed to the coordination of the data analysis and supervised the project	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Project administration|Resources|Supervision	YES
5792384	29388075	PET	2	reconstruction, motion correction	reconstruction, motion correction	Performed the experiments	Investigation	YES
5792384	29388075	YM	2	provided assistance in the data analysis	provided assistance in the data analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
3041748	21303504	AB	2	did the bibliographic research and wrote the first draft and the final version of the manuscript	did the bibliographic research and wrote the first draft and the final version of the manuscript	Wrote the paper	Formal analysis|Writing - Original Draft	YES
3041748	21303504	FC	2	read the first version and contributed editorial and critical modifications	read the first version and contributed editorial and critical modifications	-	-	NO
3041748	21303504	GA	2	read the first version and contributed editorial and critical modifications	read the first version and contributed editorial and critical modifications	-	-	NO
3041748	21303504	LP	2	initiated the article and made substantial revisions to the earlier draft	initiated the article and made substantial revisions to the earlier draft	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
3041748	21303504	PMM	2	read the first version and contributed editorial and critical modifications	read the first version and contributed editorial and critical modifications	-	-	NO
5585194	28919907	PIN	2	detection and provided assistance to zs	detection and provided assistance to zs	Performed the experiments	Investigation	YES
5585194	28919907	RZ	2	performed gene transformation, auxin	performed gene transformation, auxin	Performed the experiments	Investigation	YES
5585194	28919907	SX	2	provided technical assistance to wh	provided technical assistance to wh	Performed the experiments	Investigation	YES
5585194	28919907	TL	2	designed the experiments and analyzed the data	designed the experiments and analyzed the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5585194	28919907	WG	2	performed patch clamp experiments	performed patch clamp experiments	Performed the experiments	Investigation	YES
5585194	28919907	WH	2	performed root growth parameter measurement	performed root growth parameter measurement	Performed the experiments	Investigation	YES
5585194	28919907	WZ	2	performed patch clamp experiments	performed patch clamp experiments	Performed the experiments	Investigation	YES
5585194	28919907	XD	2	performed cross hybridization and qpcr experiments and provided assistance to zs and tl	performed cross hybridization and qpcr experiments and provided assistance to zs and tl	Performed the experiments	Investigation	YES
5585194	28919907	ZS	2	conceived the research plans, supervised and complemented the writing	conceived the research plans, supervised and complemented the writing	Conceived and designed the experiments|Wrote the paper	Conceptualization|Supervision	YES
5369179	28347275	ADF	1	Analyzed data|Collected and processed sequence data	Analyzed data	Analyzed the data	Formal analysis	YES
5369179	28347275	ADF	1	Analyzed data|Collected and processed sequence data	Collected and processed sequence data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5369179	28347275	JG	1	Analyzed data|Collected and processed sequence data	Analyzed data	Analyzed the data	Formal analysis	YES
5369179	28347275	JG	1	Analyzed data|Collected and processed sequence data	Collected and processed sequence data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5369179	28347275	JL	1	Performed experiments|Analyzed data|Collected and processed sequence data	Performed experiments	Performed the experiments	Investigation	YES
5369179	28347275	JL	1	Performed experiments|Analyzed data|Collected and processed sequence data	Analyzed data	Analyzed the data	Formal analysis	YES
5369179	28347275	JL	1	Performed experiments|Analyzed data|Collected and processed sequence data	Collected and processed sequence data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5369179	28347275	JM	1	Conceived and designed experiments|Analyzed data|Collected and processed sequence data	Conceived and designed experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5369179	28347275	JM	1	Conceived and designed experiments|Analyzed data|Collected and processed sequence data	Analyzed data	Analyzed the data	Formal analysis	YES
5369179	28347275	JM	1	Conceived and designed experiments|Analyzed data|Collected and processed sequence data	Collected and processed sequence data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5369179	28347275	JRM	1	Conceived and designed experiments|Analyzed data|Collected and processed sequence data	Conceived and designed experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5369179	28347275	JRM	1	Conceived and designed experiments|Analyzed data|Collected and processed sequence data	Analyzed data	Analyzed the data	Formal analysis	YES
5369179	28347275	JRM	1	Conceived and designed experiments|Analyzed data|Collected and processed sequence data	Collected and processed sequence data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5369179	28347275	KATS	1	Conceived and designed experiments|Analyzed data|Wrote paper|Collected and processed sequence data	Conceived and designed experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5369179	28347275	KATS	1	Conceived and designed experiments|Analyzed data|Wrote paper|Collected and processed sequence data	Analyzed data	Analyzed the data	Formal analysis	YES
5369179	28347275	KATS	1	Conceived and designed experiments|Analyzed data|Wrote paper|Collected and processed sequence data	Wrote paper	Wrote the paper	Writing - Original Draft	YES
5369179	28347275	KATS	1	Conceived and designed experiments|Analyzed data|Wrote paper|Collected and processed sequence data	Collected and processed sequence data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5369179	28347275	KPS	1	Performed experiments|Analyzed data	Performed experiments	Performed the experiments	Investigation	YES
5369179	28347275	KPS	1	Performed experiments|Analyzed data	Analyzed data	Analyzed the data	Formal analysis	YES
5369179	28347275	NDY	1	Conceived and designed experiments|Analyzed data|Wrote paper	Conceived and designed experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5369179	28347275	NDY	1	Conceived and designed experiments|Analyzed data|Wrote paper	Analyzed data	Analyzed the data	Formal analysis	YES
5369179	28347275	NDY	1	Conceived and designed experiments|Analyzed data|Wrote paper	Wrote paper	Wrote the paper	Writing - Original Draft	YES
5369179	28347275	PT	1	Conceived and designed experiments|Analyzed data	Conceived and designed experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5369179	28347275	PT	1	Conceived and designed experiments|Analyzed data	Analyzed data	Analyzed the data	Formal analysis	YES
5369179	28347275	PZ	1	Performed experiments|Analyzed data|Wrote paper|Collected and processed sequence data	Performed experiments	Performed the experiments	Investigation	YES
5369179	28347275	PZ	1	Performed experiments|Analyzed data|Wrote paper|Collected and processed sequence data	Analyzed data	Analyzed the data	Formal analysis	YES
5369179	28347275	PZ	1	Performed experiments|Analyzed data|Wrote paper|Collected and processed sequence data	Wrote paper	Wrote the paper	Writing - Original Draft	YES
5369179	28347275	PZ	1	Performed experiments|Analyzed data|Wrote paper|Collected and processed sequence data	Collected and processed sequence data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5369179	28347275	RD	1	Performed experiments	Performed experiments	Performed the experiments	Investigation	YES
5369179	28347275	RMS	1	Conceived and designed experiments|Analyzed data|Collected and processed sequence data	Conceived and designed experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5369179	28347275	RMS	1	Conceived and designed experiments|Analyzed data|Collected and processed sequence data	Analyzed data	Analyzed the data	Formal analysis	YES
5369179	28347275	RMS	1	Conceived and designed experiments|Analyzed data|Collected and processed sequence data	Collected and processed sequence data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5369179	28347275	TR	1	Performed experiments|Analyzed data|Collected and processed sequence data	Performed experiments	Performed the experiments	Investigation	YES
5369179	28347275	TR	1	Performed experiments|Analyzed data|Collected and processed sequence data	Analyzed data	Analyzed the data	Formal analysis	YES
5369179	28347275	TR	1	Performed experiments|Analyzed data|Collected and processed sequence data	Collected and processed sequence data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
3041996	21284843	Damiaan Denys	2	is responsible for the full content of the manuscript	is responsible for the full content of the manuscript	-	-	NO
4406860	25901833	AIB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406860	25901833	AIB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406860	25901833	AIB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406860	25901833	DGR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406860	25901833	DGR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406860	25901833	DGR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406860	25901833	DGR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5369223	28347272	ACP	2	designed and performed laboratory experiments	designed and performed laboratory experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5369223	28347272	All authors	2	worked on the text, read and approved the final manuscript	worked on the text, read and approved the final manuscript	Performed the experiments|Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5369223	28347272	CW	2	designed and performed laboratory experiments	designed and performed laboratory experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5369223	28347272	ET	2	ran experiments of pathway-focussed analysis, analysed results, and wrote the code to generate bed files in the genome-wide analysis	ran experiments of pathway-focussed analysis, analysed results, and wrote the code to generate bed files in the genome-wide analysis	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Software|Writing - Original Draft	YES
5369223	28347272	JMK	2	conceived the idea, provided guidance in interpretation of results	conceived the idea, provided guidance in interpretation of results	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Supervision	YES
5369223	28347272	MA	2	conceived methods, performed computational experiments of pathway-focussed analysis, ran all experiments of genome-wide analysis, analysed the results, produced tables/ figures	conceived methods, performed computational experiments of pathway-focussed analysis, ran all experiments of genome-wide analysis, analysed the results, produced tables/ figures	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation|Visualization	YES
5369223	28347272	RBR	2	conceived the idea, provided guidance in interpretation of results|designed and performed laboratory experiments	conceived the idea, provided guidance in interpretation of results	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Supervision	YES
5369223	28347272	RBR	2	conceived the idea, provided guidance in interpretation of results|designed and performed laboratory experiments	designed and performed laboratory experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5585197	28919905	AK	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5585197	28919905	All authors	2	read and approved the manuscript	read and approved the manuscript	-	-	NO
5585197	28919905	BZ	2	analyzed data and wrote the manuscript	analyzed data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5585197	28919905	DL	2	analyzed data and wrote the manuscript	analyzed data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5585197	28919905	LC	2	assist during the experiments	assist during the experiments	Performed the experiments	Investigation	YES
5585197	28919905	PC	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5585197	28919905	RZ	2	conceived and designed the research	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5585197	28919905	XK	2	assist during the experiments	assist during the experiments	Performed the experiments	Investigation	YES
5585197	28919905	XL	2	assist during the experiments	assist during the experiments	Performed the experiments	Investigation	YES
5585197	28919905	YZ	2	analyzed data and wrote the manuscript	analyzed data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5818391	29460190	All authors	2	contributed to the conception and design of the study	contributed to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5818391	29460190	H. All	2	authors contributed to the interpretation of the data and to drafting and critically revising the manuscript	authors contributed to the interpretation of the data and to drafting and critically revising the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft|Writing - Review & Editing	YES
4364127	25821596	Abulie Takele	2	conceptualized and assisted with design of the study as well as data interpretation and critical review of the paper	conceptualized and assisted with design of the study as well as data interpretation and critical review of the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Review & Editing	YES
4364127	25821596	Dabere Nigatu	2	assisted with conceptualization of the study and data interpretation and critically reviewed the paper	assisted with conceptualization of the study and data interpretation and critically reviewed the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Review & Editing	YES
4364127	25821596	Demewoz Haile	2	assisted with the study design, analyses, and interpretation, drafted, and critically revised the paper	assisted with the study design, analyses, and interpretation, drafted, and critically revised the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
4364127	25821596	Tesfaye Gizaw	2	managed data collection, assisted the data analysis, and critically reviewed the paper	managed data collection, assisted the data analysis, and critically reviewed the paper	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Formal analysis|Investigation|Writing - Review & Editing	YES
4364127	25821596	Tesfaye Setegn	2	conceived the idea of the study, managed data collection, analyses, and interpretation, and critically reviewed the paper	conceived the idea of the study, managed data collection, analyses, and interpretation, and critically reviewed the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Data curation|Formal analysis|Investigation|Writing - Review & Editing	YES
3096919	21473781	AS	2	participated in study conception, design and manuscript preparation	participated in study conception, design and manuscript preparation	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
3096919	21473781	CK	2	participated in study conception, design and manuscript preparation	participated in study conception, design and manuscript preparation	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
3096919	21473781	CP	2	participated in study conception, design and manuscript preparation	participated in study conception, design and manuscript preparation	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
3096919	21473781	JD	2	participated in study conception, design and manuscript preparation	participated in study conception, design and manuscript preparation	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
3096919	21473781	JW	2	led the qualitative analyses and participated in manuscript preparation	led the qualitative analyses and participated in manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3096919	21473781	TS	2	participated in study conception, design and manuscript preparation	participated in study conception, design and manuscript preparation	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
3096919	21473781	VG	2	participated in study coordination, analyses and manuscript preparation	participated in study coordination, analyses and manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Project administration|Writing - Original Draft	YES
3096919	21473781	WM	2	conceived of the study, obtained funding, led its design, coordination, and manuscript preparation and participated in the analyses	conceived of the study, obtained funding, led its design, coordination, and manuscript preparation and participated in the analyses	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Funding acquisition|Methodology|Project administration|Writing - Original Draft	YES
4406865	25902144	BAM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4406865	25902144	BAM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406865	25902144	BAM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406865	25902144	JRG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4406865	25902144	JRG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406865	25902144	KJB	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4406865	25902144	KJB	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4406865	25902144	MP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4406865	25902144	MP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4406865	25902144	MP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4518155	26258144	Liming Gao	2	contributed equally to this work and served as co-first authors	contributed equally to this work and served as co-first authors	-	-	NO
4518155	26258144	Yingying Zhu	2	contributed equally to this work and served as co-first authors	contributed equally to this work and served as co-first authors	-	-	NO
5369228	28347276	HB	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5369228	28347276	KM	2	performed the rna seq data analysis	performed the rna seq data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5369228	28347276	MB	2	performed the rna seq data analysis|performed data analysis and revised the manuscript	performed the rna seq data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5369228	28347276	MB	2	performed the rna seq data analysis|performed data analysis and revised the manuscript	performed data analysis and revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5369228	28347276	MM	2	conceived, designed and supervised all aspects of the study|wrote the manuscript|performed data analysis and revised the manuscript	conceived, designed and supervised all aspects of the study	Conceived and designed the experiments	Conceptualization|Methodology|Supervision	YES
5369228	28347276	MM	2	conceived, designed and supervised all aspects of the study|wrote the manuscript|performed data analysis and revised the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5369228	28347276	MM	2	conceived, designed and supervised all aspects of the study|wrote the manuscript|performed data analysis and revised the manuscript	performed data analysis and revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5369228	28347276	SA	2	performed experiments|performed the rna seq data analysis|wrote the manuscript	performed experiments	Performed the experiments	Investigation	YES
5369228	28347276	SA	2	performed experiments|performed the rna seq data analysis|wrote the manuscript	performed the rna seq data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5369228	28347276	SA	2	performed experiments|performed the rna seq data analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5369228	28347276	YL	2	performed experiments|performed the rna seq data analysis|wrote the manuscript	performed experiments	Performed the experiments	Investigation	YES
5369228	28347276	YL	2	performed experiments|performed the rna seq data analysis|wrote the manuscript	performed the rna seq data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5369228	28347276	YL	2	performed experiments|performed the rna seq data analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3110117	21539727	GM	2	is responsible for the full content of the manuscript	is responsible for the full content of the manuscript	-	-	NO
5833889	29492787	CMdB	2	contributed to the preparation and execution of experiments	contributed to the preparation and execution of experiments	Performed the experiments	Investigation	YES
5833889	29492787	EEV	2	contributed to the execution of the experiments, analysis and interpretation of data, and manuscript writing	contributed to the execution of the experiments, analysis and interpretation of data, and manuscript writing	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft	YES
5833889	29492787	JB	2	contributed to the manuscript correction and expert interpretation of results	contributed to the manuscript correction and expert interpretation of results	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5833889	29492787	MKS	2	contributed to the execution of the experiments, analysis and interpretation of data, and manuscript writing	contributed to the execution of the experiments, analysis and interpretation of data, and manuscript writing	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft	YES
5833889	29492787	SMA	2	contributed to the execution of the experiments, analysis and interpretation of data, and manuscript writing	contributed to the execution of the experiments, analysis and interpretation of data, and manuscript writing	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft	YES
5833889	29492787	TCdW	2	contributed to the design of the study, expert interpretation of results, and manuscript correction	contributed to the design of the study, expert interpretation of results, and manuscript correction	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
4407885	25905783	CY	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4407885	25905783	CY	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4407885	25905783	JSS	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4407885	25905783	JSS	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4407885	25905783	JSS	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4407885	25905783	SS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
3117801	21586129	HW	2	provided mentoring and extensive editing of the final manuscript	provided mentoring and extensive editing of the final manuscript	Wrote the paper	Writing - Review & Editing	YES
3117801	21586129	NK	2	provided mentoring and extensive editing of the final manuscript	provided mentoring and extensive editing of the final manuscript	Wrote the paper	Writing - Review & Editing	YES
3117801	21586129	SL	2	provided mentoring and extensive editing of the final manuscript	provided mentoring and extensive editing of the final manuscript	Wrote the paper	Writing - Review & Editing	YES
3117801	21586129	SS	2	wrote the initial draft	wrote the initial draft	Wrote the paper	Writing - Original Draft	YES
5585570	28919900	DD	2	designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
5585570	28919900	FS	2	performed the research	performed the research	Performed the experiments	Investigation	YES
5585570	28919900	GF	2	performed the research	performed the research	Performed the experiments	Investigation	YES
5585570	28919900	JF	2	performed the research	performed the research	Performed the experiments	Investigation	YES
5585570	28919900	KM	2	designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
5585570	28919900	SM	2	performed the research	performed the research	Performed the experiments	Investigation	YES
5585570	28919900	The authors	2	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	Performed the experiments	Investigation	YES
3120773	21569490	All	2	the named authors have read and approved the final manuscript	the named authors have read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
3120773	21569490	All authors	2	contributed equally to the writing of this paper	contributed equally to the writing of this paper	Wrote the paper	Writing - Original Draft	YES
3123279	21645346	GB	2	conceived and developed the paper topic, and wrote the first draft	conceived and developed the paper topic, and wrote the first draft	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
3123279	21645346	SK	2	contributed biographical and art historical material, and edited the manuscript	contributed biographical and art historical material, and edited the manuscript	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Review & Editing	YES
5585741	28919899	JP	2	provided input and revisions to the manuscript	provided input and revisions to the manuscript	Wrote the paper	Writing - Review & Editing	YES
5585741	28919899	KK	2	provided input and revisions to the manuscript	provided input and revisions to the manuscript	Wrote the paper	Writing - Review & Editing	YES
5849748	29536291	EG	2	participated in the design and coordination of the study, analyzed the results, and helped draft the manuscript	participated in the design and coordination of the study, analyzed the results, and helped draft the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Project administration|Writing - Original Draft	YES
5849748	29536291	ES	2	led the clinical applications and study design, study support, clinical image quality optimization, and statistical analysis of the results	led the clinical applications and study design, study support, clinical image quality optimization, and statistical analysis of the results	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology|Visualization	YES
5849748	29536291	LB	2	led the physics aspects, system calibrations, and phantom studies for image quality validation	led the physics aspects, system calibrations, and phantom studies for image quality validation	Performed the experiments|Analyzed the data	Validation|Visualization	YES
5849748	29536291	RG	2	participated in design and coordination of the study	participated in design and coordination of the study	Conceived and designed the experiments	Methodology|Project administration	YES
5849748	29536291	SBH	2	participated in the design and coordination of the study, analyzed the results, and helped draft the manuscript	participated in the design and coordination of the study, analyzed the results, and helped draft the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Project administration|Writing - Original Draft	YES
5849748	29536291	TK	2	led the algorithms and camera design, image acquisition, reconstruction implementation, and optimization	led the algorithms and camera design, image acquisition, reconstruction implementation, and optimization	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Investigation|Software|Visualization	YES
5371188	28356085	DS	2	conceived and designed the experiments and wrote the manuscript	conceived and designed the experiments and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
5371188	28356085	GEL	2	participated in data analysis and manuscript preparations	participated in data analysis and manuscript preparations	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5371188	28356085	JJ	2	performed qrt-pcr experiments and sample collection	performed qrt-pcr experiments and sample collection	Performed the experiments	Investigation	YES
5371188	28356085	QZ	2	participated in result interpretation	participated in result interpretation	Analyzed the data	Formal analysis	YES
5371188	28356085	SY	2	performed qrt-pcr experiments and sample collection	performed qrt-pcr experiments and sample collection	Performed the experiments	Investigation	YES
5371188	28356085	SZ	2	participated in result interpretation	participated in result interpretation	Analyzed the data	Formal analysis	YES
5371188	28356085	YG	2	performed bioinformatics and statistical analysis and qpcr experiments, and also was a major contributor to manuscript preparation	performed bioinformatics and statistical analysis and qpcr experiments, and also was a major contributor to manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5371188	28356085	YH	2	participated in data analysis and manuscript preparations	participated in data analysis and manuscript preparations	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4407886	25905638	AIdS	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4407886	25905638	AIdS	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4407886	25905638	AIdS	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4407886	25905638	EVP	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4407886	25905638	EVP	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4407886	25905638	EVP	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4407886	25905638	FAK	PLoS5	Conceived and designed the experiments|Wrote the paper|Critical appraisal of study results	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4407886	25905638	FAK	PLoS5	Conceived and designed the experiments|Wrote the paper|Critical appraisal of study results	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4407886	25905638	FAK	PLoS5	Conceived and designed the experiments|Wrote the paper|Critical appraisal of study results	Critical appraisal of study results	-	-	NO
4407886	25905638	FJMvdM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4407886	25905638	FJMvdM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4407886	25905638	FJMvdM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4407886	25905638	GYHL	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4407886	25905638	GYHL	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4407886	25905638	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Critical appraisal of study results	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4407886	25905638	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Critical appraisal of study results	Performed the experiments	Performed the experiments	Investigation	YES
4407886	25905638	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Critical appraisal of study results	Analyzed the data	Analyzed the data	Formal analysis	YES
4407886	25905638	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Critical appraisal of study results	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4407886	25905638	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Critical appraisal of study results	Critical appraisal of study results	-	-	NO
4407886	25905638	MVH	PLoS5	Conceived and designed the experiments|Wrote the paper|Critical appraisal of study results	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4407886	25905638	MVH	PLoS5	Conceived and designed the experiments|Wrote the paper|Critical appraisal of study results	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4407886	25905638	MVH	PLoS5	Conceived and designed the experiments|Wrote the paper|Critical appraisal of study results	Critical appraisal of study results	-	-	NO
4407886	25905638	NH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4407886	25905638	NH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4407886	25905638	NH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4407886	25905638	NH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4407886	25905638	SCC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Critical appraisal of study results	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4407886	25905638	SCC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Critical appraisal of study results	Performed the experiments	Performed the experiments	Investigation	YES
4407886	25905638	SCC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Critical appraisal of study results	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4407886	25905638	SCC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Critical appraisal of study results	Critical appraisal of study results	-	-	NO
4407887	25905635	FL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4407887	25905635	HHY	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4407887	25905635	HHY	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4407887	25905635	JWX	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4407887	25905635	LD	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4407887	25905635	NZ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4407887	25905635	PZ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4407887	25905635	RHY	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4407887	25905635	SJL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4407887	25905635	WJL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4407887	25905635	XDC	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4407887	25905635	XQJ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4407887	25905635	YG	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4407887	25905635	YH	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4407887	25905635	YZZ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5585744	28919901	AA	7	Scientist -Mentor of SG; Planned the experiments, supervised the progress of research and contributed in preparing the manuscript	Scientist -Mentor of SG; Planned the experiments, supervised the progress of research and contributed in preparing the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Supervision|Writing - Original Draft	YES
5585744	28919901	AG	7	helped in field experimentation and phenotyping	helped in field experimentation and phenotyping	Performed the experiments	Investigation	YES
5585744	28919901	AK	7	helped in manuscript development	helped in manuscript development	-	-	NO
5585744	28919901	HS	7	field phenotyping for shoot fly resistance	field phenotyping for shoot fly resistance	Performed the experiments	Investigation	YES
5585744	28919901	LN	7	supervised the progress of research	supervised the progress of research	-	Supervision	YES
5585744	28919901	SD	7	planning of experiments, molecular biology support, genotyping data analysis	planning of experiments, molecular biology support, genotyping data analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5585744	28919901	SG	7	PI of the Project; executed the research and made major contribution to developing the manuscript	PI of the Project; executed the research and made major contribution to developing the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5882483	29616365	All authors	2	contributed to the data acquisition at their respective institutions	contributed to the data acquisition at their respective institutions	Performed the experiments	Investigation	YES
5882483	29616365	DF	2	contributed to the design of this study	contributed to the design of this study	Conceived and designed the experiments	Methodology	YES
5882483	29616365	FL	2	contributed to the design of this study	contributed to the design of this study	Conceived and designed the experiments	Methodology	YES
5882483	29616365	KK	2	contributed to the design of this study	contributed to the design of this study	Conceived and designed the experiments	Methodology	YES
5882483	29616365	MC	2	contributed to the design of this study	contributed to the design of this study	Conceived and designed the experiments	Methodology	YES
5882483	29616365	ME	2	contributed to the design of this study|contributed to the design of this study	contributed to the design of this study	Conceived and designed the experiments	Methodology	YES
5882483	29616365	ME	2	contributed to the design of this study|contributed to the design of this study	contributed to the design of this study	Conceived and designed the experiments	Methodology	YES
5882483	29616365	MT	2	contributed to the design of this study	contributed to the design of this study	Conceived and designed the experiments	Methodology	YES
5882483	29616365	NM	2	contributed to the design of this study	contributed to the design of this study	Conceived and designed the experiments	Methodology	YES
5371264	28351377	BK	2	designed the experiments and wrote the manuscript	designed the experiments and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5371264	28351377	SH	2	designed the experiments, interpreted the data and was major contributor in writing the manuscript	designed the experiments, interpreted the data and was major contributor in writing the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5371264	28351377	SR	2	designed, performed and analyzed the experiments	designed, performed and analyzed the experiments	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5371264	28351377	TL	2	wrote the program for the promotor analysis	wrote the program for the promotor analysis	Contributed reagents/materials/analysis tools|Wrote the paper	Software|Writing - Original Draft	YES
4407888	25906258	CHH	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4407888	25906258	CHH	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4407888	25906258	JS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4407888	25906258	JS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4407888	25906258	LZZ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4407888	25906258	MLJ	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4407888	25906258	MLJ	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4407888	25906258	RFW	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4407888	25906258	RFW	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4407888	25906258	XKL	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4407888	25906258	XKL	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4407888	25906258	XL	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4407888	25906258	XL	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4407888	25906258	XS	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
3160882	21740573	FC	2	wrote the first draft of the manuscript|revised and edited subsequent drafts	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
3160882	21740573	FC	2	wrote the first draft of the manuscript|revised and edited subsequent drafts	revised and edited subsequent drafts	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3160882	21740573	RT	2	revised and edited subsequent drafts	revised and edited subsequent drafts	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3160882	21740573	SB	2	revised and edited subsequent drafts	revised and edited subsequent drafts	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5904089	29666972	AI	2	took part in the study design, data collection and analysis, and manuscript preparation	took part in the study design, data collection and analysis, and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5904089	29666972	GD	2	helped in the data analysis	helped in the data analysis	Analyzed the data	Formal analysis	YES
5904089	29666972	IS	2	took part in the study design, data collection and analysis, and manuscript preparation	took part in the study design, data collection and analysis, and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5904089	29666972	LB	2	contributed in the data collection, data analysis, and manuscript preparation	contributed in the data collection, data analysis, and manuscript preparation	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft	YES
5904089	29666972	NH	2	contributed in the data collection	contributed in the data collection	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5904089	29666972	SP	2	contributed in the data collection and data analysis	contributed in the data collection and data analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5904089	29666972	SS	2	helped in the data analysis	helped in the data analysis	Analyzed the data	Formal analysis	YES
5904089	29666972	SSG	2	contributed in the study design	contributed in the study design	Conceived and designed the experiments	Methodology	YES
4407889	25906064	CS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4407889	25906064	DPM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4407889	25906064	JGL	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4407889	25906064	JGL	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4407889	25906064	ZC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4407889	25906064	ZC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4407889	25906064	ZC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4407889	25906064	ZC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3225294	21974866	CC	2	performed a literature review, participated in the paper design, performed the initial draft manuscript and provided substantive reviews of the later drafts	performed a literature review, participated in the paper design, performed the initial draft manuscript and provided substantive reviews of the later drafts	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
3225294	21974866	CS	2	helped design the research study and paper, contributed to analysis of the data, redrafting and critically reviewed the manuscript for intellectual content	helped design the research study and paper, contributed to analysis of the data, redrafting and critically reviewed the manuscript for intellectual content	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
3225294	21974866	KB	2	helped design the research study and paper, contributed to analysis of the data, redrafting and critically reviewed the manuscript for intellectual content	helped design the research study and paper, contributed to analysis of the data, redrafting and critically reviewed the manuscript for intellectual content	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
3225294	21974866	LA	2	helped design the research study and paper, contributed to analysis of the data, redrafting and critically reviewed the manuscript for intellectual content	helped design the research study and paper, contributed to analysis of the data, redrafting and critically reviewed the manuscript for intellectual content	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
3225294	21974866	MD	2	participated in the paper design and redrafted the manuscript	participated in the paper design and redrafted the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
3225294	21974866	RZS	2	helped design the research study, contributed to analysis of the data, participated in paper design, redrafting and critically reviewed the manuscript for intellectual content	helped design the research study, contributed to analysis of the data, participated in paper design, redrafting and critically reviewed the manuscript for intellectual content	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
3225294	21974866	SV	2	participated in paper design and critically reviewed the manuscript for intellectual content	participated in paper design and critically reviewed the manuscript for intellectual content	Conceived and designed the experiments|Wrote the paper	Writing - Review & Editing	YES
4575727	26425365	All authors	2	have made substantial contributions to design, analysis, and interpretation of data and have been involved in drafting and revising the paper critically for important intellectual content and have given final approval of the version to be published	have made substantial contributions to design, analysis, and interpretation of data and have been involved in drafting and revising the paper critically for important intellectual content and have given final approval of the version to be published	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5930296	29717385	AC	2	assisted with the acquisitions and analysis of data|assisted with the acquisitions and analysis of data	assisted with the acquisitions and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5930296	29717385	AC	2	assisted with the acquisitions and analysis of data|assisted with the acquisitions and analysis of data	assisted with the acquisitions and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5930296	29717385	PE	2	assisted with the acquisitions and analysis of data	assisted with the acquisitions and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5930296	29717385	XH	2	assisted with the acquisitions and analysis of data	assisted with the acquisitions and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5585745	28919903	AL	2	conceived the review|prepared the manuscript|edited the manuscript	conceived the review	Conceived and designed the experiments	Conceptualization	YES
5585745	28919903	AL	2	conceived the review|prepared the manuscript|edited the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5585745	28919903	AL	2	conceived the review|prepared the manuscript|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5585745	28919903	HG	2	conceived the review|analyzed the literature data|prepared the manuscript|edited the manuscript	conceived the review	Conceived and designed the experiments	Conceptualization	YES
5585745	28919903	HG	2	conceived the review|analyzed the literature data|prepared the manuscript|edited the manuscript	analyzed the literature data	Analyzed the data	Formal analysis	YES
5585745	28919903	HG	2	conceived the review|analyzed the literature data|prepared the manuscript|edited the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5585745	28919903	HG	2	conceived the review|analyzed the literature data|prepared the manuscript|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5585745	28919903	IA	2	conceived the review|analyzed the literature data|prepared the manuscript	conceived the review	Conceived and designed the experiments	Conceptualization	YES
5585745	28919903	IA	2	conceived the review|analyzed the literature data|prepared the manuscript	analyzed the literature data	Analyzed the data	Formal analysis	YES
5585745	28919903	IA	2	conceived the review|analyzed the literature data|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5585745	28919903	LDB	2	edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
3274462	22251457	E. All	2	authors contributed to the development of the final manuscript and approve the final version	authors contributed to the development of the final manuscript and approve the final version	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4407890	25906399	JP	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4407890	25906399	LM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4407890	25906399	LM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4407890	25906399	LM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4407890	25906399	LM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4407890	25906399	PP	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4407890	25906399	PP	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4407890	25906399	VJ	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5372324	28356071	CC	PLoS52	analyzed the rna seq data	analyzed the rna seq data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5372324	28356071	DH	PLoS52	designed the study|wrote the manuscript|revised the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5372324	28356071	DH	PLoS52	designed the study|wrote the manuscript|revised the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5372324	28356071	DH	PLoS52	designed the study|wrote the manuscript|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5372324	28356071	HB	PLoS52	designed the study|revised the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5372324	28356071	HB	PLoS52	designed the study|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5372324	28356071	SR	PLoS52	analyzed the rna seq data	analyzed the rna seq data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5372324	28356071	SS	PLoS52	designed the study|performed the experiments|analyzed the rna seq data|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5372324	28356071	SS	PLoS52	designed the study|performed the experiments|analyzed the rna seq data|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5372324	28356071	SS	PLoS52	designed the study|performed the experiments|analyzed the rna seq data|wrote the manuscript	analyzed the rna seq data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5372324	28356071	SS	PLoS52	designed the study|performed the experiments|analyzed the rna seq data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5372324	28356071	YW	PLoS52	designed the study|revised the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5372324	28356071	YW	PLoS52	designed the study|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4519537	26258137	Ana Pecina	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
4519537	26258137	Raquel M. Fernandez	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
5585746	28919898	AA-C	2	performance of the research and technical support	performance of the research and technical support	Performed the experiments	Investigation	YES
5585746	28919898	AL	2	performance of the research and technical support	performance of the research and technical support	Performed the experiments	Investigation	YES
5585746	28919898	CR-I	2	performance of the research and technical support	performance of the research and technical support	Performed the experiments	Investigation	YES
5585746	28919898	EZ-G	2	performance of the research and technical support	performance of the research and technical support	Performed the experiments	Investigation	YES
5585746	28919898	FL-M	2	performance of the research, data collection, and writing of the manuscript	performance of the research, data collection, and writing of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5585746	28919898	FS	2	design and performance of the research, data collection, data interpretation, and writing of the manuscript	design and performance of the research, data collection, data interpretation, and writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5585746	28919898	L-L	2	design and performance of the research, data collection and data analysis, and writing of the manuscript	design and performance of the research, data collection and data analysis, and writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5585746	28919898	LL-L	2	design of the research, data interpretation, and writing of the manuscript	design of the research, data interpretation, and writing of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5585746	28919898	NE	2	design and performance of the research, data collection and data analysis, and writing of the manuscript	design and performance of the research, data collection and data analysis, and writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5585746	28919898	ZG	2	performance of the research and technical support	performance of the research and technical support	Performed the experiments	Investigation	YES
4407892	25905707	AB	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4407892	25905707	AB	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4407892	25905707	ABT	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4407892	25905707	LL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4407892	25905707	LL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4407892	25905707	LL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4407892	25905707	LL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4407892	25905707	MDB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4407892	25905707	MDB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4407892	25905707	MDB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4407892	25905707	MDB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4407892	25905707	NJ	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4407892	25905707	NJ	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4407892	25905707	RW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5953912	29766354	All authors	2	contributed equally to this work|discussed the results and implications and commented on the manuscript	contributed equally to this work	-	-	NO
5953912	29766354	All authors	2	contributed equally to this work|discussed the results and implications and commented on the manuscript	discussed the results and implications and commented on the manuscript	-	-	NO
5372332	28356072	DvS	2	provided materials and strains|wrote the manuscript	provided materials and strains	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5372332	28356072	DvS	2	provided materials and strains|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5372332	28356072	FB	2	contributed to sequence assembly and annotation	contributed to sequence assembly and annotation	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5372332	28356072	JM	2	provided materials and strains|wrote the manuscript	provided materials and strains	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5372332	28356072	JM	2	provided materials and strains|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5372332	28356072	KK	2	provided methods & experimental outlines	provided methods & experimental outlines	Performed the experiments	-	YES
5372332	28356072	PK	2	contributed to sequence assembly and annotation|performed experiments|wrote the manuscript	contributed to sequence assembly and annotation	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5372332	28356072	PK	2	contributed to sequence assembly and annotation|performed experiments|wrote the manuscript	performed experiments	Performed the experiments	Investigation	YES
5372332	28356072	PK	2	contributed to sequence assembly and annotation|performed experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4407893	25906394	CH	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4407893	25906394	CH	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4407893	25906394	JMG	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4407893	25906394	JMG	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4407893	25906394	JRM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4407893	25906394	JRM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4407893	25906394	JRM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4407893	25906394	JRM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4407893	25906394	JRM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4407893	25906394	KT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4407893	25906394	KT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4407893	25906394	KT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4407893	25906394	KT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4407893	25906394	KT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4407893	25906394	MD	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4407893	25906394	MD	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3292805	22177365	JA	2	originated the article, did the research and wrote a first rough draft of the manuscript together|all read the first version and contributed editorial and critical suggestions|made substantial revisions to the earlier draft and worked toward the final draft|have both read and approved the final version of the manuscript	originated the article, did the research and wrote a first rough draft of the manuscript together	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
3292805	22177365	JA	2	originated the article, did the research and wrote a first rough draft of the manuscript together|all read the first version and contributed editorial and critical suggestions|made substantial revisions to the earlier draft and worked toward the final draft|have both read and approved the final version of the manuscript	all read the first version and contributed editorial and critical suggestions	-	-	NO
3292805	22177365	JA	2	originated the article, did the research and wrote a first rough draft of the manuscript together|all read the first version and contributed editorial and critical suggestions|made substantial revisions to the earlier draft and worked toward the final draft|have both read and approved the final version of the manuscript	made substantial revisions to the earlier draft and worked toward the final draft	Performed the experiments|Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3292805	22177365	JA	2	originated the article, did the research and wrote a first rough draft of the manuscript together|all read the first version and contributed editorial and critical suggestions|made substantial revisions to the earlier draft and worked toward the final draft|have both read and approved the final version of the manuscript	have both read and approved the final version of the manuscript	-	-	NO
3292805	22177365	TJ	2	originated the article, did the research and wrote a first rough draft of the manuscript together|all read the first version and contributed editorial and critical suggestions	originated the article, did the research and wrote a first rough draft of the manuscript together	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
3292805	22177365	TJ	2	originated the article, did the research and wrote a first rough draft of the manuscript together|all read the first version and contributed editorial and critical suggestions	all read the first version and contributed editorial and critical suggestions	-	-	NO
5986691	29869186	AMG	2	contributed to the design of the study and have been involved in revising the manuscript critically for important intellectual content	contributed to the design of the study and have been involved in revising the manuscript critically for important intellectual content	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5986691	29869186	BFHl	2	performed all coding and analysis of the work and drafted this paper	performed all coding and analysis of the work and drafted this paper	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5986691	29869186	BFHt	2	contributed to the design of the study and have been involved in revising the manuscript critically for important intellectual content	contributed to the design of the study and have been involved in revising the manuscript critically for important intellectual content	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5986691	29869186	KT	2	contributed to the design of the study and have been involved in revising the manuscript critically for important intellectual content|assisted with the coding and analysis and were essential in revising the manuscript	contributed to the design of the study and have been involved in revising the manuscript critically for important intellectual content	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5986691	29869186	KT	2	contributed to the design of the study and have been involved in revising the manuscript critically for important intellectual content|assisted with the coding and analysis and were essential in revising the manuscript	assisted with the coding and analysis and were essential in revising the manuscript	Wrote the paper	Writing - Review & Editing	YES
5986691	29869186	LM	2	acquired all patient data used in this study	acquired all patient data used in this study	Performed the experiments	Investigation	YES
5986691	29869186	RE	2	acquired all patient data used in this study	acquired all patient data used in this study	Performed the experiments	Investigation	YES
5986691	29869186	TM	2	selected patients to be included in the study	selected patients to be included in the study	-	-	NO
5986691	29869186	VC	2	assisted with the coding and analysis and were essential in revising the manuscript	assisted with the coding and analysis and were essential in revising the manuscript	Wrote the paper	Writing - Review & Editing	YES
5585773	28919904	AC-V	2	wrote the manuscript and had primary responsibility for the final content|collected and analyzed biochemical data	wrote the manuscript and had primary responsibility for the final content	Wrote the paper	Writing - Original Draft	YES
5585773	28919904	AC-V	2	wrote the manuscript and had primary responsibility for the final content|collected and analyzed biochemical data	collected and analyzed biochemical data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5585773	28919904	AS	2	collected and analyzed biochemical data	collected and analyzed biochemical data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5585773	28919904	CB	2	collected and analyzed histological data	collected and analyzed histological data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5585773	28919904	CD	2	analyzed statistically the data	analyzed statistically the data	Analyzed the data	Formal analysis	YES
5585773	28919904	DB	2	collected and analyzed biochemical data	collected and analyzed biochemical data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5585773	28919904	DF	2	collected and analyzed morpho-physiological data	collected and analyzed morpho-physiological data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5585773	28919904	DL	2	wrote the manuscript and had primary responsibility for the final content|integrated morpho-physiological, histological and biochemical data	wrote the manuscript and had primary responsibility for the final content	Wrote the paper	Writing - Original Draft	YES
5585773	28919904	DL	2	wrote the manuscript and had primary responsibility for the final content|integrated morpho-physiological, histological and biochemical data	integrated morpho-physiological, histological and biochemical data	Performed the experiments	Investigation	YES
5585773	28919904	DP	2	wrote the manuscript and had primary responsibility for the final content|collected and analyzed biochemical data	wrote the manuscript and had primary responsibility for the final content	Wrote the paper	Writing - Original Draft	YES
5585773	28919904	DP	2	wrote the manuscript and had primary responsibility for the final content|collected and analyzed biochemical data	collected and analyzed biochemical data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5585773	28919904	LP	2	wrote the manuscript and had primary responsibility for the final content|integrated morpho-physiological, histological and biochemical data|analyzed statistically the data	wrote the manuscript and had primary responsibility for the final content	Wrote the paper	Writing - Original Draft	YES
5585773	28919904	LP	2	wrote the manuscript and had primary responsibility for the final content|integrated morpho-physiological, histological and biochemical data|analyzed statistically the data	integrated morpho-physiological, histological and biochemical data	Performed the experiments	Investigation	YES
5585773	28919904	LP	2	wrote the manuscript and had primary responsibility for the final content|integrated morpho-physiological, histological and biochemical data|analyzed statistically the data	analyzed statistically the data	Analyzed the data	Formal analysis	YES
5585773	28919904	LR	2	wrote the manuscript and had primary responsibility for the final content|analyzed statistically the data	wrote the manuscript and had primary responsibility for the final content	Wrote the paper	Writing - Original Draft	YES
5585773	28919904	LR	2	wrote the manuscript and had primary responsibility for the final content|analyzed statistically the data	analyzed statistically the data	Analyzed the data	Formal analysis	YES
5585773	28919904	SJ	2	wrote the manuscript and had primary responsibility for the final content|collected and analyzed histological data	wrote the manuscript and had primary responsibility for the final content	Wrote the paper	Writing - Original Draft	YES
5585773	28919904	SJ	2	wrote the manuscript and had primary responsibility for the final content|collected and analyzed histological data	collected and analyzed histological data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5585773	28919904	SR	2	collected and analyzed morpho-physiological data	collected and analyzed morpho-physiological data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5372343	28356070	DW	2	collected the datasets, designed and developed the pipelines, performed and analysed the experiments, and wrote the paper	collected the datasets, designed and developed the pipelines, performed and analysed the experiments, and wrote the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5372343	28356070	FG	2	provided conceptual and technical guidance for pan-genome and rearrangement and commented on the experimental results	provided conceptual and technical guidance for pan-genome and rearrangement and commented on the experimental results	Conceived and designed the experiments	Conceptualization|Supervision	YES
5372343	28356070	KN	2	made major contribution to revise the paper, provided guidance for inversion mechanisms and pan-genome and commented on the experimental results	made major contribution to revise the paper, provided guidance for inversion mechanisms and pan-genome and commented on the experimental results	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Review & Editing	YES
5372343	28356070	LW	2	directed this research, designed the methods, analysed the experimental results, and wrote the paper	directed this research, designed the methods, analysed the experimental results, and wrote the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Supervision|Writing - Original Draft	YES
5372343	28356070	SL	2	provided conceptual and technical guidance for pan-genome and rearrangement and commented on the experimental results	provided conceptual and technical guidance for pan-genome and rearrangement and commented on the experimental results	Conceived and designed the experiments	Conceptualization|Supervision	YES
3292958	22244084	DJS	2	conceived of and wrote this manuscript	conceived of and wrote this manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
3734625	23371464	All authors	2	were involved in reviewing the report	were involved in reviewing the report	-	-	NO
3734625	23371464	C.A.D.	2	took part in data collection|took part in data interpretation and manuscript writing	took part in data collection	Performed the experiments	Investigation	YES
3734625	23371464	C.A.D.	2	took part in data collection|took part in data interpretation and manuscript writing	took part in data interpretation and manuscript writing	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3734625	23371464	E.J.T.R.	2	participated in the patient accrual|took part in data interpretation and manuscript writing	participated in the patient accrual	-	-	NO
3734625	23371464	E.J.T.R.	2	participated in the patient accrual|took part in data interpretation and manuscript writing	took part in data interpretation and manuscript writing	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3734625	23371464	G.S.S.	2	performed the data analysis|took part in data interpretation and manuscript writing	performed the data analysis	Analyzed the data	Formal analysis	YES
3734625	23371464	G.S.S.	2	performed the data analysis|took part in data interpretation and manuscript writing	took part in data interpretation and manuscript writing	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3734625	23371464	H.v.T.	2	performed the data analysis	performed the data analysis	Analyzed the data	Formal analysis	YES
3734625	23371464	J.M.B.d.M.	2	coordinated the study|took part in data collection|took part in collection and processing of tumor samples	coordinated the study	-	Project administration	YES
3734625	23371464	J.M.B.d.M.	2	coordinated the study|took part in data collection|took part in collection and processing of tumor samples	took part in data collection	Performed the experiments	Investigation	YES
3734625	23371464	J.M.B.d.M.	2	coordinated the study|took part in data collection|took part in collection and processing of tumor samples	took part in collection and processing of tumor samples	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
3734625	23371464	J.W.	2	took part in collection and processing of tumor samples	took part in collection and processing of tumor samples	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
3734625	23371464	L.J.v.V.	2	were responsible for the study design and development of the protocol	were responsible for the study design and development of the protocol	Conceived and designed the experiments	Methodology	YES
3734625	23371464	M.J.v.d.V.	2	were responsible for the study design and development of the protocol|took part in collection and processing of tumor samples	were responsible for the study design and development of the protocol	Conceived and designed the experiments	Methodology	YES
3734625	23371464	M.J.v.d.V.	2	were responsible for the study design and development of the protocol|took part in collection and processing of tumor samples	took part in collection and processing of tumor samples	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
3734625	23371464	M.K.	2	took part in data collection	took part in data collection	Performed the experiments	Investigation	YES
3734625	23371464	R.M.H.R.	2	participated in the patient accrual	participated in the patient accrual	-	-	NO
3734625	23371464	S.C.L.	2	were responsible for the study design and development of the protocol|took part in data interpretation and manuscript writing	were responsible for the study design and development of the protocol	Conceived and designed the experiments	Methodology	YES
3734625	23371464	S.C.L.	2	were responsible for the study design and development of the protocol|took part in data interpretation and manuscript writing	took part in data interpretation and manuscript writing	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3734625	23371464	V.P.R.	2	took part in data collection	took part in data collection	Performed the experiments	Investigation	YES
3734625	23371464	W.H.v.H.	2	were responsible for the study design and development of the protocol|ensured financing	were responsible for the study design and development of the protocol	Conceived and designed the experiments	Methodology	YES
3734625	23371464	W.H.v.H.	2	were responsible for the study design and development of the protocol|ensured financing	ensured financing	-	-	NO
6006002	29916115	AC	2	contributed to the design of this work|analyzed the data and performed the dosimetry calculations|wrote the manuscript	contributed to the design of this work	Conceived and designed the experiments	-	YES
6006002	29916115	AC	2	contributed to the design of this work|analyzed the data and performed the dosimetry calculations|wrote the manuscript	analyzed the data and performed the dosimetry calculations	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6006002	29916115	AC	2	contributed to the design of this work|analyzed the data and performed the dosimetry calculations|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6006002	29916115	AM	2	were responsible for the patient recruitment	were responsible for the patient recruitment	Performed the experiments	Investigation	YES
6006002	29916115	AS	2	were in charge of the imaging studies and interpretation of the images|revised the manuscript	were in charge of the imaging studies and interpretation of the images	Analyzed the data	Formal analysis|Visualization	YES
6006002	29916115	AS	2	were in charge of the imaging studies and interpretation of the images|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
6006002	29916115	DJG	2	were responsible for the patient recruitment	were responsible for the patient recruitment	Performed the experiments	Investigation	YES
6006002	29916115	FA	2	analyzed the data and performed the dosimetry calculations	analyzed the data and performed the dosimetry calculations	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6006002	29916115	JG	2	contributed to the design of this work|were in charge of the imaging studies and interpretation of the images|revised the manuscript	contributed to the design of this work	Conceived and designed the experiments	-	YES
6006002	29916115	JG	2	contributed to the design of this work|were in charge of the imaging studies and interpretation of the images|revised the manuscript	were in charge of the imaging studies and interpretation of the images	Analyzed the data	Formal analysis|Visualization	YES
6006002	29916115	JG	2	contributed to the design of this work|were in charge of the imaging studies and interpretation of the images|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
6006002	29916115	SG-G	2	were responsible for the patient recruitment|revised the manuscript	were responsible for the patient recruitment	Performed the experiments	Investigation	YES
6006002	29916115	SG-G	2	were responsible for the patient recruitment|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4407894	25906187	BM	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4407894	25906187	CH	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4407894	25906187	CL	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Obtained permission for field site use	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4407894	25906187	CL	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Obtained permission for field site use	Performed the experiments	Performed the experiments	Investigation	YES
4407894	25906187	CL	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Obtained permission for field site use	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4407894	25906187	CL	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Obtained permission for field site use	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4407894	25906187	CL	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Obtained permission for field site use	Obtained permission for field site use	-	-	NO
4407894	25906187	HY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4407894	25906187	HY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4407894	25906187	HY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4407894	25906187	HY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4407894	25906187	HY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4407894	25906187	LS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4407894	25906187	LS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4407894	25906187	LS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4407894	25906187	Z. Li	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4407894	25906187	Z. Liu	PLoS5	Performed the experiments|Obtained permission for field site use	Performed the experiments	Performed the experiments	Investigation	YES
4407894	25906187	Z. Liu	PLoS5	Performed the experiments|Obtained permission for field site use	Obtained permission for field site use	-	-	NO
5586210	28919902	All authors	2	have participated in this research and approved the final manuscript	have participated in this research and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5586210	28919902	BZ	2	performed experiments and helped revised manuscript	performed experiments and helped revised manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5586210	28919902	CL	2	performed experiments and helped revised manuscript	performed experiments and helped revised manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5586210	28919902	XC	2	performed experiments and helped revised manuscript	performed experiments and helped revised manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5586210	28919902	XR	2	designed the experiments, discussed results, and revised this manuscript	designed the experiments, discussed results, and revised this manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5586210	28919902	YL	2	designed the experiments, performed the research, wrote and revised this manuscript	designed the experiments, performed the research, wrote and revised this manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5586210	28919902	YQ	2	performed experiments and helped revised manuscript	performed experiments and helped revised manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5586210	28919902	ZL	2	designed the experiments and provided all samples tested	designed the experiments and provided all samples tested	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources	YES
5374549	28361671	All authors	2	contributed to the editing of the manuscript, and all authors read and approved the final manuscript	contributed to the editing of the manuscript, and all authors read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5374549	28361671	CC	2	assisted with the analysis of lm3 dataset	assisted with the analysis of lm3 dataset	Analyzed the data	Formal analysis	YES
5374549	28361671	JM	2	conceived and designed the project|made intellectual contributions to the whole project|wrote the manuscript	conceived and designed the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5374549	28361671	JM	2	conceived and designed the project|made intellectual contributions to the whole project|wrote the manuscript	made intellectual contributions to the whole project	-	-	NO
5374549	28361671	JM	2	conceived and designed the project|made intellectual contributions to the whole project|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5374549	28361671	JZ	2	collected the datasets, constructed the protein sequence database and implemented the evaluation workflow	collected the datasets, constructed the protein sequence database and implemented the evaluation workflow	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Software	YES
5374549	28361671	KS	2	conceived and designed the project|made intellectual contributions to the whole project	conceived and designed the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5374549	28361671	KS	2	conceived and designed the project|made intellectual contributions to the whole project	made intellectual contributions to the whole project	-	-	NO
5374549	28361671	LL	2	collected the datasets, constructed the protein sequence database and implemented the evaluation workflow	collected the datasets, constructed the protein sequence database and implemented the evaluation workflow	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Software	YES
5374549	28361671	XF	2	collected the datasets, constructed the protein sequence database and implemented the evaluation workflow|wrote the manuscript	collected the datasets, constructed the protein sequence database and implemented the evaluation workflow	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Software	YES
5374549	28361671	XF	2	collected the datasets, constructed the protein sequence database and implemented the evaluation workflow|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5374549	28361671	YZ	2	made intellectual contributions to the whole project	made intellectual contributions to the whole project	-	-	NO
3305603	22243994	AF	2	wrote the responses to commentaries	wrote the responses to commentaries	Wrote the paper	Writing - Original Draft	YES
3305603	22243994	AH	2	wrote the commentaries	wrote the commentaries	Wrote the paper	Writing - Original Draft	YES
3305603	22243994	AM	2	wrote the commentaries	wrote the commentaries	Wrote the paper	Writing - Original Draft	YES
3305603	22243994	CP	2	wrote the commentaries	wrote the commentaries	Wrote the paper	Writing - Original Draft	YES
3305603	22243994	DP	2	wrote the commentaries	wrote the commentaries	Wrote the paper	Writing - Original Draft	YES
3305603	22243994	EM	2	wrote the commentaries	wrote the commentaries	Wrote the paper	Writing - Original Draft	YES
3305603	22243994	GG	2	wrote the commentaries	wrote the commentaries	Wrote the paper	Writing - Original Draft	YES
3305603	22243994	HD	2	wrote the commentaries	wrote the commentaries	Wrote the paper	Writing - Original Draft	YES
3305603	22243994	HP	2	wrote the commentaries	wrote the commentaries	Wrote the paper	Writing - Original Draft	YES
3305603	22243994	JC	2	wrote the commentaries	wrote the commentaries	Wrote the paper	Writing - Original Draft	YES
3305603	22243994	JParis	2	wrote the commentaries	wrote the commentaries	Wrote the paper	Writing - Original Draft	YES
3305603	22243994	JPhillips	2	wrote the general general introduction and conclusion, as well as the introductions to the individual conclusions	wrote the general general introduction and conclusion, as well as the introductions to the individual conclusions	Wrote the paper	Writing - Original Draft	YES
3305603	22243994	JW	2	wrote the commentaries	wrote the commentaries	Wrote the paper	Writing - Original Draft	YES
3305603	22243994	MC	2	wrote the commentaries	wrote the commentaries	Wrote the paper	Writing - Original Draft	YES
3305603	22243994	MF	2	wrote the commentaries	wrote the commentaries	Wrote the paper	Writing - Original Draft	YES
3305603	22243994	MS	2	wrote the commentaries	wrote the commentaries	Wrote the paper	Writing - Original Draft	YES
3305603	22243994	NG	2	wrote the commentaries	wrote the commentaries	Wrote the paper	Writing - Original Draft	YES
3305603	22243994	OW	2	wrote the commentaries	wrote the commentaries	Wrote the paper	Writing - Original Draft	YES
3305603	22243994	PZ	2	wrote the commentaries	wrote the commentaries	Wrote the paper	Writing - Original Draft	YES
3305603	22243994	RP	2	wrote the commentaries	wrote the commentaries	Wrote the paper	Writing - Original Draft	YES
3305603	22243994	SL	2	wrote the commentaries	wrote the commentaries	Wrote the paper	Writing - Original Draft	YES
3305603	22243994	SW	2	wrote the commentaries	wrote the commentaries	Wrote the paper	Writing - Original Draft	YES
3305603	22243994	TS	2	wrote the commentaries	wrote the commentaries	Wrote the paper	Writing - Original Draft	YES
3305603	22243994	WK	2	wrote the commentaries	wrote the commentaries	Wrote the paper	Writing - Original Draft	YES
4407895	25906151	AJW	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4407895	25906151	AJW	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4407895	25906151	AJW	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4407895	25906151	DWR	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4407895	25906151	DWR	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4407895	25906151	FB	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Bibliographic research|Programme	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4407895	25906151	FB	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Bibliographic research|Programme	Performed the experiments	Performed the experiments	Investigation	YES
4407895	25906151	FB	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Bibliographic research|Programme	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4407895	25906151	FB	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Bibliographic research|Programme	Bibliographic research	-	Formal analysis	YES
4407895	25906151	FB	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Bibliographic research|Programme	Programme	-	-	NO
4407895	25906151	FMB	PLoS5	Analyzed the data|Wrote the paper|Data management|Development of the entomological database	Analyzed the data	Analyzed the data	Formal analysis	YES
4407895	25906151	FMB	PLoS5	Analyzed the data|Wrote the paper|Data management|Development of the entomological database	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4407895	25906151	FMB	PLoS5	Analyzed the data|Wrote the paper|Data management|Development of the entomological database	Data management	Analyzed the data	Data curation	YES
4407895	25906151	FMB	PLoS5	Analyzed the data|Wrote the paper|Data management|Development of the entomological database	Development of the entomological database	Contributed reagents/materials/analysis tools	Software	YES
4407895	25906151	JL	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4407895	25906151	JL	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4407895	25906151	LEH	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4407895	25906151	LEH	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4407895	25906151	RA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Data management	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4407895	25906151	RA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Data management	Analyzed the data	Analyzed the data	Formal analysis	YES
4407895	25906151	RA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Data management	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4407895	25906151	RA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Data management	Data management	Analyzed the data	Data curation	YES
4407895	25906151	RR	PLoS5	Analyzed the data|Wrote the paper|Bibliographic research|Data management	Analyzed the data	Analyzed the data	Formal analysis	YES
4407895	25906151	RR	PLoS5	Analyzed the data|Wrote the paper|Bibliographic research|Data management	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4407895	25906151	RR	PLoS5	Analyzed the data|Wrote the paper|Bibliographic research|Data management	Bibliographic research	-	Formal analysis	YES
4407895	25906151	RR	PLoS5	Analyzed the data|Wrote the paper|Bibliographic research|Data management	Data management	Analyzed the data	Data curation	YES
4407895	25906151	SM	PLoS5	Analyzed the data|Wrote the paper|Bibliographic research|Data management	Analyzed the data	Analyzed the data	Formal analysis	YES
4407895	25906151	SM	PLoS5	Analyzed the data|Wrote the paper|Bibliographic research|Data management	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4407895	25906151	SM	PLoS5	Analyzed the data|Wrote the paper|Bibliographic research|Data management	Bibliographic research	-	Formal analysis	YES
4407895	25906151	SM	PLoS5	Analyzed the data|Wrote the paper|Bibliographic research|Data management	Data management	Analyzed the data	Data curation	YES
4407895	25906151	TN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Data management|Development of the entomological database	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4407895	25906151	TN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Data management|Development of the entomological database	Analyzed the data	Analyzed the data	Formal analysis	YES
4407895	25906151	TN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Data management|Development of the entomological database	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4407895	25906151	TN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Data management|Development of the entomological database	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4407895	25906151	TN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Data management|Development of the entomological database	Data management	Analyzed the data	Data curation	YES
4407895	25906151	TN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Data management|Development of the entomological database	Development of the entomological database	Contributed reagents/materials/analysis tools	Software	YES
4771871	26989507	Bereket Damtew	2	participated in data collection, analysis, and inference of findings and narrated this paper for publication	participated in data collection, analysis, and inference of findings and narrated this paper for publication	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4771871	26989507	Fisseha Wudineh	2	was the lead author who led the designing, data collection, analysis, and interpretation of results	was the lead author who led the designing, data collection, analysis, and interpretation of results	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6031553	29974391	AS	2	participated in the design of the clinical trial, recruitment and treatment of the patients, data analysis and interpretation and manuscript preparation	participated in the design of the clinical trial, recruitment and treatment of the patients, data analysis and interpretation and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
6031553	29974391	All co-authors	2	participated in the critical review of the manuscript	participated in the critical review of the manuscript	Wrote the paper	Writing - Review & Editing	YES
6031553	29974391	GB	2	contributed to the data analysis and interpretation	contributed to the data analysis and interpretation	Analyzed the data	Formal analysis	YES
6031553	29974391	JG	2	contributed to the data analysis and interpretation	contributed to the data analysis and interpretation	Analyzed the data	Formal analysis	YES
6031553	29974391	JS	2	contributed to the design of the trial and recruitment and treatment of the patients	contributed to the design of the trial and recruitment and treatment of the patients	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6031553	29974391	JT	2	participated in the design of the clinical trial, recruitment and treatment of patients and interpretation of data	participated in the design of the clinical trial, recruitment and treatment of patients and interpretation of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
6031553	29974391	KSG	2	participated in the design of the dosimetric method and software, dosimetric calculations, data analysis and interpretation and manuscript preparation	participated in the design of the dosimetric method and software, dosimetric calculations, data analysis and interpretation and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Software|Writing - Original Draft	YES
6031553	29974391	ML	2	contributed to the design of the dosimetric method and software used	contributed to the design of the dosimetric method and software used	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Methodology|Software	YES
6031553	29974391	NM	2	contributed to the design and implementation of the analysis of inter-operator variability and dosimetric calculations	contributed to the design and implementation of the analysis of inter-operator variability and dosimetric calculations	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6031553	29974391	PB	2	participated in the design of the dosimetric method used in the trial	participated in the design of the dosimetric method used in the trial	Conceived and designed the experiments|Performed the experiments	Methodology	YES
6031553	29974391	RH	2	contributed to the design and implementation of the analysis of inter-operator variability and dosimetric calculations	contributed to the design and implementation of the analysis of inter-operator variability and dosimetric calculations	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5591374	28928757	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5591374	28928757	LL	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5591374	28928757	LT	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5591374	28928757	SA	2	provided advice and edited the manuscript	provided advice and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5591374	28928757	TY	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5591374	28928757	WC	2	provided advice and edited the manuscript	provided advice and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5591374	28928757	XW	2	wrote the manuscript|analyzed the experiments data|performed experiments	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5591374	28928757	XW	2	wrote the manuscript|analyzed the experiments data|performed experiments	analyzed the experiments data	Analyzed the data	Formal analysis	YES
5591374	28928757	XW	2	wrote the manuscript|analyzed the experiments data|performed experiments	performed experiments	Performed the experiments	Investigation	YES
5591374	28928757	YZ	2	provided advice and edited the manuscript	provided advice and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5515031	28691436	CB	2	designed and conducted the statistical analysis	designed and conducted the statistical analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis	YES
5515031	28691436	DS	2	assisted in designing and conducting the studies	assisted in designing and conducting the studies	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5515031	28691436	JA	2	wrote the first draft and all authors contributed in finalizing and approving the manuscript	wrote the first draft and all authors contributed in finalizing and approving the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5515031	28691436	JLKF	2	assisted in designing and conducting the studies	assisted in designing and conducting the studies	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5515031	28691436	PD	2	designed and conducted the statistical analysis	designed and conducted the statistical analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis	YES
5515031	28691436	RT	2	oversaw the laboratory component and analysis	oversaw the laboratory component and analysis	Performed the experiments	Investigation|Supervision	YES
5515031	28691436	SP	2	designed and conducted the statistical analysis	designed and conducted the statistical analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis	YES
5515031	28691436	SS	2	assisted in designing and conducting the studies	assisted in designing and conducting the studies	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5374554	28361700	All	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5374554	28361700	H.D.H.	2	supervised the progress of the study, provided guidance in its design and coordination|helped to draft and revise the manuscript	supervised the progress of the study, provided guidance in its design and coordination	Conceived and designed the experiments	Methodology|Project administration|Supervision	YES
5374554	28361700	H.D.H.	2	supervised the progress of the study, provided guidance in its design and coordination|helped to draft and revise the manuscript	helped to draft and revise the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5374554	28361700	W.H.K.	2	helped to draft and revise the manuscript	helped to draft and revise the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5374554	28361700	W.L.C.	2	helped to draft and revise the manuscript	helped to draft and revise the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5374554	28361700	Y.C.L.	2	proposed and conducted this study	proposed and conducted this study	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
3313846	22206616	ARJ	2	drafted the first version of the manuscript	drafted the first version of the manuscript	Wrote the paper	Writing - Original Draft	YES
3313846	22206616	All authors	2	made substantial contributions to conception and design of the manuscript, revising the manuscript critically for important intellectual content, and have read and approved the final manuscript	made substantial contributions to conception and design of the manuscript, revising the manuscript critically for important intellectual content, and have read and approved the final manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
3313846	22206616	Each author	2	participated sufficiently to take public responsibility for the content	participated sufficiently to take public responsibility for the content	-	-	NO
4523651	26266262	Wei Du	2	contributed equally to the work	contributed equally to the work	-	-	NO
4523651	26266262	Xiujuan Wu	2	contributed equally to the work	contributed equally to the work	-	-	NO
4407896	25905776	DB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4407896	25905776	JC	PLoS5	Conceived and designed the experiments|Analyzed the data|Critical revision of manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4407896	25905776	JC	PLoS5	Conceived and designed the experiments|Analyzed the data|Critical revision of manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4407896	25905776	JC	PLoS5	Conceived and designed the experiments|Analyzed the data|Critical revision of manuscript	Critical revision of manuscript	Wrote the paper	Writing - Review & Editing	YES
4407896	25905776	ND	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4407896	25905776	ND	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4407896	25905776	NO	PLoS5	Conceived and designed the experiments|Critical revision of manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4407896	25905776	NO	PLoS5	Conceived and designed the experiments|Critical revision of manuscript	Critical revision of manuscript	Wrote the paper	Writing - Review & Editing	YES
4407896	25905776	TH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4407896	25905776	TH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4407896	25905776	TH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4407896	25905776	TS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4407896	25905776	TS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4407896	25905776	TS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4407896	25905776	TS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4407896	25905776	WY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4407896	25905776	WY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4407896	25905776	WY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
6051951	30022353	AS	2	critically revised the article for an important intellectual content	critically revised the article for an important intellectual content	Wrote the paper	Writing - Review & Editing	YES
6051951	30022353	BG	2	analyzed and interpreted the data|collected and assembled the data	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
6051951	30022353	BG	2	analyzed and interpreted the data|collected and assembled the data	collected and assembled the data	Performed the experiments	Investigation	YES
6051951	30022353	IB	2	analyzed and interpreted the data	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
6051951	30022353	JN	2	conceived and designed the study|analyzed and interpreted the data|drafted the article	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6051951	30022353	JN	2	conceived and designed the study|analyzed and interpreted the data|drafted the article	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
6051951	30022353	JN	2	conceived and designed the study|analyzed and interpreted the data|drafted the article	drafted the article	Wrote the paper	Writing - Original Draft	YES
6051951	30022353	JP	2	analyzed and interpreted the data|collected and assembled the data	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
6051951	30022353	JP	2	analyzed and interpreted the data|collected and assembled the data	collected and assembled the data	Performed the experiments	Investigation	YES
6051951	30022353	KH	2	critically revised the article for an important intellectual content	critically revised the article for an important intellectual content	Wrote the paper	Writing - Review & Editing	YES
6051951	30022353	SK	2	analyzed and interpreted the data	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
6051951	30022353	VS	2	analyzed and interpreted the data|collected and assembled the data	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
6051951	30022353	VS	2	analyzed and interpreted the data|collected and assembled the data	collected and assembled the data	Performed the experiments	Investigation	YES
6051951	30022353	WJ	2	conceived and designed the study|analyzed and interpreted the data|drafted the article	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6051951	30022353	WJ	2	conceived and designed the study|analyzed and interpreted the data|drafted the article	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
6051951	30022353	WJ	2	conceived and designed the study|analyzed and interpreted the data|drafted the article	drafted the article	Wrote the paper	Writing - Original Draft	YES
5374575	28359300	BTB	2	wrote the final manuscript, with editorial	wrote the final manuscript, with editorial	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5374575	28359300	CM	2	coordinated the collection of samples and sequencing|assisted with the with editorial	coordinated the collection of samples and sequencing	Performed the experiments	Investigation|Project administration	YES
5374575	28359300	CM	2	coordinated the collection of samples and sequencing|assisted with the with editorial	assisted with the with editorial	-	-	NO
5374575	28359300	DW	2	coordinated the collection of samples and sequencing|assisted with the with editorial	coordinated the collection of samples and sequencing	Performed the experiments	Investigation|Project administration	YES
5374575	28359300	DW	2	coordinated the collection of samples and sequencing|assisted with the with editorial	assisted with the with editorial	-	-	NO
5374575	28359300	SRP	2	assisted with the with editorial	assisted with the with editorial	-	-	NO
5591530	28928758	AkR	PLoS52	provided scientific support for the lab work|analyzed the data|wrote the manuscript and all authors revised the manuscript	provided scientific support for the lab work	Performed the experiments	Investigation	YES
5591530	28928758	AkR	PLoS52	provided scientific support for the lab work|analyzed the data|wrote the manuscript and all authors revised the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5591530	28928758	AkR	PLoS52	provided scientific support for the lab work|analyzed the data|wrote the manuscript and all authors revised the manuscript	wrote the manuscript and all authors revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5591530	28928758	AmR	PLoS52	analyzed the data|wrote the manuscript and all authors revised the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5591530	28928758	AmR	PLoS52	analyzed the data|wrote the manuscript and all authors revised the manuscript	wrote the manuscript and all authors revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5591530	28928758	GB	PLoS52	conceived the project|wrote the manuscript and all authors revised the manuscript	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5591530	28928758	GB	PLoS52	conceived the project|wrote the manuscript and all authors revised the manuscript	wrote the manuscript and all authors revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5591530	28928758	MS	PLoS52	provided scientific support for the lab work|analyzed the data	provided scientific support for the lab work	Performed the experiments	Investigation	YES
5591530	28928758	MS	PLoS52	provided scientific support for the lab work|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5591530	28928758	NB	PLoS52	conceived the project|conducted the field study and lab work|analyzed the data|wrote the manuscript and all authors revised the manuscript	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5591530	28928758	NB	PLoS52	conceived the project|conducted the field study and lab work|analyzed the data|wrote the manuscript and all authors revised the manuscript	conducted the field study and lab work	Performed the experiments	Investigation	YES
5591530	28928758	NB	PLoS52	conceived the project|conducted the field study and lab work|analyzed the data|wrote the manuscript and all authors revised the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5591530	28928758	NB	PLoS52	conceived the project|conducted the field study and lab work|analyzed the data|wrote the manuscript and all authors revised the manuscript	wrote the manuscript and all authors revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5591530	28928758	SI	PLoS52	conceived the project	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5591530	28928758	SS	PLoS52	provided scientific support for the lab work	provided scientific support for the lab work	Performed the experiments	Investigation	YES
3390269	22512887	AF	2	wrote the responses to commentaries	wrote the responses to commentaries	Wrote the paper	Writing - Original Draft	YES
3390269	22512887	AH	2	wrote the commentaries	wrote the commentaries	Wrote the paper	Writing - Original Draft	YES
3390269	22512887	AM	2	wrote the commentaries	wrote the commentaries	Wrote the paper	Writing - Original Draft	YES
3390269	22512887	CP	2	wrote the commentaries	wrote the commentaries	Wrote the paper	Writing - Original Draft	YES
3390269	22512887	DP	2	wrote the commentaries	wrote the commentaries	Wrote the paper	Writing - Original Draft	YES
3390269	22512887	EM	2	wrote the commentaries	wrote the commentaries	Wrote the paper	Writing - Original Draft	YES
3390269	22512887	GG	2	wrote the commentaries	wrote the commentaries	Wrote the paper	Writing - Original Draft	YES
3390269	22512887	HD	2	wrote the commentaries	wrote the commentaries	Wrote the paper	Writing - Original Draft	YES
3390269	22512887	HP	2	wrote the commentaries	wrote the commentaries	Wrote the paper	Writing - Original Draft	YES
3390269	22512887	JC	2	wrote the commentaries	wrote the commentaries	Wrote the paper	Writing - Original Draft	YES
3390269	22512887	JParis	2	wrote the commentaries	wrote the commentaries	Wrote the paper	Writing - Original Draft	YES
3390269	22512887	JPhillips	2	wrote the general general introduction and conclusion, as well as the introductions to the individual conclusions	wrote the general general introduction and conclusion, as well as the introductions to the individual conclusions	Wrote the paper	Writing - Original Draft	YES
3390269	22512887	JW	2	wrote the commentaries	wrote the commentaries	Wrote the paper	Writing - Original Draft	YES
3390269	22512887	MC	2	wrote the commentaries	wrote the commentaries	Wrote the paper	Writing - Original Draft	YES
3390269	22512887	MF	2	wrote the commentaries	wrote the commentaries	Wrote the paper	Writing - Original Draft	YES
3390269	22512887	MS	2	wrote the commentaries	wrote the commentaries	Wrote the paper	Writing - Original Draft	YES
3390269	22512887	NG	2	wrote the commentaries	wrote the commentaries	Wrote the paper	Writing - Original Draft	YES
3390269	22512887	OW	2	wrote the commentaries	wrote the commentaries	Wrote the paper	Writing - Original Draft	YES
3390269	22512887	PZ	2	wrote the commentaries	wrote the commentaries	Wrote the paper	Writing - Original Draft	YES
3390269	22512887	RP	2	wrote the commentaries	wrote the commentaries	Wrote the paper	Writing - Original Draft	YES
3390269	22512887	SL	2	wrote the commentaries	wrote the commentaries	Wrote the paper	Writing - Original Draft	YES
3390269	22512887	SW	2	wrote the commentaries	wrote the commentaries	Wrote the paper	Writing - Original Draft	YES
3390269	22512887	TS	2	wrote the commentaries	wrote the commentaries	Wrote the paper	Writing - Original Draft	YES
3390269	22512887	WK	2	wrote the commentaries	wrote the commentaries	Wrote the paper	Writing - Original Draft	YES
4523658	26266257	All authors	PLoS52	corrected and approved the final version of the paper	corrected and approved the final version of the paper	Wrote the paper	Writing - Review & Editing	YES
4523658	26266257	Benedikt Bunz	PLoS52	performed the experiments|analysed the data	performed the experiments	Performed the experiments	Investigation	YES
4523658	26266257	Benedikt Bunz	PLoS52	performed the experiments|analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
4523658	26266257	Jenny Zinke	PLoS52	analysed the data|wrote the paper	analysed the data	Analyzed the data	Formal analysis	YES
4523658	26266257	Jenny Zinke	PLoS52	analysed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4523658	26266257	Julia Tichy	PLoS52	conceived and designed the experiments|performed the experiments|analysed the data|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4523658	26266257	Julia Tichy	PLoS52	conceived and designed the experiments|performed the experiments|analysed the data|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
4523658	26266257	Julia Tichy	PLoS52	conceived and designed the experiments|performed the experiments|analysed the data|wrote the paper	analysed the data	Analyzed the data	Formal analysis	YES
4523658	26266257	Julia Tichy	PLoS52	conceived and designed the experiments|performed the experiments|analysed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4523658	26266257	Michel Mittelbronn	PLoS52	conceived and designed the experiments|performed the experiments|analysed the data|contributed reagents, materials, and financial support|wrote the paper|is the supervisor of the study	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4523658	26266257	Michel Mittelbronn	PLoS52	conceived and designed the experiments|performed the experiments|analysed the data|contributed reagents, materials, and financial support|wrote the paper|is the supervisor of the study	performed the experiments	Performed the experiments	Investigation	YES
4523658	26266257	Michel Mittelbronn	PLoS52	conceived and designed the experiments|performed the experiments|analysed the data|contributed reagents, materials, and financial support|wrote the paper|is the supervisor of the study	analysed the data	Analyzed the data	Formal analysis	YES
4523658	26266257	Michel Mittelbronn	PLoS52	conceived and designed the experiments|performed the experiments|analysed the data|contributed reagents, materials, and financial support|wrote the paper|is the supervisor of the study	contributed reagents, materials, and financial support	Contributed reagents/materials/analysis tools	Funding acquisition|Resources	YES
4523658	26266257	Michel Mittelbronn	PLoS52	conceived and designed the experiments|performed the experiments|analysed the data|contributed reagents, materials, and financial support|wrote the paper|is the supervisor of the study	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4523658	26266257	Michel Mittelbronn	PLoS52	conceived and designed the experiments|performed the experiments|analysed the data|contributed reagents, materials, and financial support|wrote the paper|is the supervisor of the study	is the supervisor of the study	-	Supervision	YES
4523658	26266257	Patrick N. Harter	PLoS52	conceived and designed the experiments|performed the experiments|analysed the data|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4523658	26266257	Patrick N. Harter	PLoS52	conceived and designed the experiments|performed the experiments|analysed the data|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
4523658	26266257	Patrick N. Harter	PLoS52	conceived and designed the experiments|performed the experiments|analysed the data|wrote the paper	analysed the data	Analyzed the data	Formal analysis	YES
4523658	26266257	Patrick N. Harter	PLoS52	conceived and designed the experiments|performed the experiments|analysed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4523658	26266257	Richard Meyermann	PLoS52	conceived and designed the experiments|contributed reagents, materials, and financial support	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4523658	26266257	Richard Meyermann	PLoS52	conceived and designed the experiments|contributed reagents, materials, and financial support	contributed reagents, materials, and financial support	Contributed reagents/materials/analysis tools	Funding acquisition|Resources	YES
4407903	25906326	DEO	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4407903	25906326	DEO	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4407903	25906326	DEO	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4407903	25906326	DEO	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4407903	25906326	DS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4407903	25906326	DS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4407903	25906326	DS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4407903	25906326	DS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4407903	25906326	FM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4407903	25906326	FM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4407903	25906326	FM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4407903	25906326	FM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4407903	25906326	FM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4407903	25906326	JB	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4407903	25906326	JB	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4407903	25906326	JM	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4407903	25906326	JM	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4407903	25906326	JP	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4407903	25906326	JP	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4407903	25906326	JP	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4407903	25906326	PG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4407903	25906326	PG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4407903	25906326	PG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4407903	25906326	PG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4407903	25906326	PG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4407903	25906326	RC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4407903	25906326	RC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4407903	25906326	RC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4407903	25906326	RC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4407903	25906326	RC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4407903	25906326	SP	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4407903	25906326	SP	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3403926	22621419	AF	2	wrote the responses to commentaries	wrote the responses to commentaries	Wrote the paper	Writing - Original Draft	YES
3403926	22621419	AH	2	wrote the commentaries	wrote the commentaries	Wrote the paper	Writing - Original Draft	YES
3403926	22621419	AM	2	wrote the commentaries	wrote the commentaries	Wrote the paper	Writing - Original Draft	YES
3403926	22621419	CP	2	wrote the commentaries	wrote the commentaries	Wrote the paper	Writing - Original Draft	YES
3403926	22621419	DP	2	wrote the commentaries	wrote the commentaries	Wrote the paper	Writing - Original Draft	YES
3403926	22621419	EM	2	wrote the commentaries	wrote the commentaries	Wrote the paper	Writing - Original Draft	YES
3403926	22621419	GG	2	wrote the commentaries	wrote the commentaries	Wrote the paper	Writing - Original Draft	YES
3403926	22621419	HD	2	wrote the commentaries	wrote the commentaries	Wrote the paper	Writing - Original Draft	YES
3403926	22621419	HP	2	wrote the commentaries	wrote the commentaries	Wrote the paper	Writing - Original Draft	YES
3403926	22621419	JC	2	wrote the commentaries	wrote the commentaries	Wrote the paper	Writing - Original Draft	YES
3403926	22621419	JParis	2	wrote the commentaries	wrote the commentaries	Wrote the paper	Writing - Original Draft	YES
3403926	22621419	JPhillips	2	wrote the general general introduction and conclusion, as well as the introductions to the individual conclusions	wrote the general general introduction and conclusion, as well as the introductions to the individual conclusions	Wrote the paper	Writing - Original Draft	YES
3403926	22621419	JW	2	wrote the commentaries	wrote the commentaries	Wrote the paper	Writing - Original Draft	YES
3403926	22621419	MC	2	wrote the commentaries	wrote the commentaries	Wrote the paper	Writing - Original Draft	YES
3403926	22621419	MF	2	wrote the commentaries	wrote the commentaries	Wrote the paper	Writing - Original Draft	YES
3403926	22621419	MS	2	wrote the commentaries	wrote the commentaries	Wrote the paper	Writing - Original Draft	YES
3403926	22621419	NG	2	wrote the commentaries	wrote the commentaries	Wrote the paper	Writing - Original Draft	YES
3403926	22621419	OW	2	wrote the commentaries	wrote the commentaries	Wrote the paper	Writing - Original Draft	YES
3403926	22621419	PZ	2	wrote the commentaries	wrote the commentaries	Wrote the paper	Writing - Original Draft	YES
3403926	22621419	RP	2	wrote the commentaries	wrote the commentaries	Wrote the paper	Writing - Original Draft	YES
3403926	22621419	SL	2	wrote the commentaries	wrote the commentaries	Wrote the paper	Writing - Original Draft	YES
3403926	22621419	SW	2	wrote the commentaries	wrote the commentaries	Wrote the paper	Writing - Original Draft	YES
3403926	22621419	TS	2	wrote the commentaries	wrote the commentaries	Wrote the paper	Writing - Original Draft	YES
3403926	22621419	WK	2	wrote the commentaries	wrote the commentaries	Wrote the paper	Writing - Original Draft	YES
5591575	28928761	CY	2	designed and wrote the manuscript	designed and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
5591575	28928761	LL	2	designed and wrote the manuscript	designed and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
6070453	30069805	AF	2	prepared comparison sources, organised transportation of sources, prepared phantom and assisted with imaging at all clinical sites and is the secondary author of the paper	prepared comparison sources, organised transportation of sources, prepared phantom and assisted with imaging at all clinical sites and is the secondary author of the paper	Analyzed the data|Wrote the paper	Visualization|Writing - Original Draft	YES
6070453	30069805	JG	2	performed imaging, reconstruction and image analysis and reporting at royal marsden hospital and reviewed the paper	performed imaging, reconstruction and image analysis and reporting at royal marsden hospital and reviewed the paper	Performed the experiments|Analyzed the data|Wrote the paper	Investigation|Visualization|Writing - Review & Editing	YES
6070453	30069805	JS	2	performed imaging, reconstruction and image analysis and reporting at royal surrey county hospital	performed imaging, reconstruction and image analysis and reporting at royal surrey county hospital	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
6070453	30069805	JT	2	performed imaging, reconstruction and image analysis and reporting at the christie hospital and reviewed the paper	performed imaging, reconstruction and image analysis and reporting at the christie hospital and reviewed the paper	Performed the experiments|Analyzed the data|Wrote the paper	Investigation|Visualization|Writing - Review & Editing	YES
6070453	30069805	JW	2	prepared the phantom, assisted with imaging at all clinical sites, performed data analysis and is the primary author of the paper	prepared the phantom, assisted with imaging at all clinical sites, performed data analysis and is the primary author of the paper	Analyzed the data|Wrote the paper	Formal analysis|Visualization|Writing - Original Draft	YES
6070453	30069805	KS-G	2	performed imaging, reconstruction and image analysis and reporting at lund hospital and reviewed the paper, providing extensive feedback	performed imaging, reconstruction and image analysis and reporting at lund hospital and reviewed the paper, providing extensive feedback	Performed the experiments|Analyzed the data|Wrote the paper	Investigation|Visualization|Writing - Review & Editing	YES
6070453	30069805	ML	2	performed imaging, reconstruction and image analysis and reporting at wurzburg hospital and reviewed the paper, providing extensive feedback	performed imaging, reconstruction and image analysis and reporting at wurzburg hospital and reviewed the paper, providing extensive feedback	Performed the experiments|Analyzed the data|Wrote the paper	Investigation|Visualization|Writing - Review & Editing	YES
6070453	30069805	MS	2	performed imaging, reconstruction and image analysis and reporting at erasmus hospital	performed imaging, reconstruction and image analysis and reporting at erasmus hospital	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
6070453	30069805	PS	2	performed imaging, reconstruction and image analysis and reporting at motol hospital and reviewed paper	performed imaging, reconstruction and image analysis and reporting at motol hospital and reviewed paper	Performed the experiments|Analyzed the data|Wrote the paper	Investigation|Visualization|Writing - Review & Editing	YES
6070453	30069805	SS	2	performed imaging, reconstruction and image analysis and reporting at wurzburg hospital	performed imaging, reconstruction and image analysis and reporting at wurzburg hospital	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
5374587	28361703	All authors	2	edited and approved the final version of the manuscript	edited and approved the final version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5374587	28361703	FK	2	interpreted the results and wrote the paper	interpreted the results and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5374587	28361703	SS	2	conceived and conducted the research|carried out the theoretical proof|interpreted the results and wrote the paper	conceived and conducted the research	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5374587	28361703	SS	2	conceived and conducted the research|carried out the theoretical proof|interpreted the results and wrote the paper	carried out the theoretical proof	Performed the experiments	Formal analysis|Investigation	YES
5374587	28361703	SS	2	conceived and conducted the research|carried out the theoretical proof|interpreted the results and wrote the paper	interpreted the results and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5374587	28361703	TT	2	conceived and conducted the research|interpreted the results and wrote the paper	conceived and conducted the research	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5374587	28361703	TT	2	conceived and conducted the research|interpreted the results and wrote the paper	interpreted the results and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3023067	21253452	ASH	2	conceived the study, participated in its design and coordination|performed the data collection and statistical analysis	conceived the study, participated in its design and coordination	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
3023067	21253452	ASH	2	conceived the study, participated in its design and coordination|performed the data collection and statistical analysis	performed the data collection and statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3023067	21253452	BM	2	drafted the manuscript|participated in the design of the study	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
3023067	21253452	BM	2	drafted the manuscript|participated in the design of the study	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
3023067	21253452	MI	2	conceived the study, participated in its design and coordination|performed the data collection and statistical analysis	conceived the study, participated in its design and coordination	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
3023067	21253452	MI	2	conceived the study, participated in its design and coordination|performed the data collection and statistical analysis	performed the data collection and statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3023067	21253452	NM	2	conceived the study, participated in its design and coordination|drafted the manuscript	conceived the study, participated in its design and coordination	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
3023067	21253452	NM	2	conceived the study, participated in its design and coordination|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4407904	25905915	APB	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4407904	25905915	APB	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4407904	25905915	EA	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4407904	25905915	JD	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4407904	25905915	JEAB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4407904	25905915	JEAB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4407904	25905915	JEAB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4407904	25905915	JEAB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4407904	25905915	MV	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4407904	25905915	MV	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4407904	25905915	ND	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4407904	25905915	ND	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4407904	25905915	ND	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4407904	25905915	STB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
3447659	22866822	BM	2	was co-organizer of the workshop and facilitated the majority of the discussions	was co-organizer of the workshop and facilitated the majority of the discussions	-	-	NO
3447659	22866822	R. All	2	authors agreed on the final content of the english version	authors agreed on the final content of the english version	-	-	NO
3447659	22866822	TT	2	organized and informed the content of the original workshop on ancillary care and provided substantial input to the original draft of the manuscript	organized and informed the content of the original workshop on ancillary care and provided substantial input to the original draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
5591819	28928759	AV	2	designed the experiment|performed the experiment	designed the experiment	Conceived and designed the experiments	Methodology	YES
5591819	28928759	AV	2	designed the experiment|performed the experiment	performed the experiment	Performed the experiments	Investigation	YES
5591819	28928759	All authors	2	discussed the results and implications and commented on the manuscript at all stages	discussed the results and implications and commented on the manuscript at all stages	-	-	NO
5591819	28928759	DM	2	did the extractions, analytical analysis, and data treatment|developed and validated the method	did the extractions, analytical analysis, and data treatment	Analyzed the data	Formal analysis	YES
5591819	28928759	DM	2	did the extractions, analytical analysis, and data treatment|developed and validated the method	developed and validated the method	Performed the experiments	Methodology|Validation	YES
5591819	28928759	ES	2	did the extractions, analytical analysis, and data treatment|developed and validated the method	did the extractions, analytical analysis, and data treatment	Analyzed the data	Formal analysis	YES
5591819	28928759	ES	2	did the extractions, analytical analysis, and data treatment|developed and validated the method	developed and validated the method	Performed the experiments	Methodology|Validation	YES
5591819	28928759	FM	2	designed the experiment	designed the experiment	Conceived and designed the experiments	Methodology	YES
5591819	28928759	GC	2	designed the experiment|performed the experiment|did the extractions, analytical analysis, and data treatment|developed and validated the method	designed the experiment	Conceived and designed the experiments	Methodology	YES
5591819	28928759	GC	2	designed the experiment|performed the experiment|did the extractions, analytical analysis, and data treatment|developed and validated the method	performed the experiment	Performed the experiments	Investigation	YES
5591819	28928759	GC	2	designed the experiment|performed the experiment|did the extractions, analytical analysis, and data treatment|developed and validated the method	did the extractions, analytical analysis, and data treatment	Analyzed the data	Formal analysis	YES
5591819	28928759	GC	2	designed the experiment|performed the experiment|did the extractions, analytical analysis, and data treatment|developed and validated the method	developed and validated the method	Performed the experiments	Methodology|Validation	YES
5591819	28928759	GD	2	designed the experiment|performed the experiment	designed the experiment	Conceived and designed the experiments	Methodology	YES
5591819	28928759	GD	2	designed the experiment|performed the experiment	performed the experiment	Performed the experiments	Investigation	YES
5591819	28928759	LZ	2	designed the experiment|performed the experiment	designed the experiment	Conceived and designed the experiments	Methodology	YES
5591819	28928759	LZ	2	designed the experiment|performed the experiment	performed the experiment	Performed the experiments	Investigation	YES
5591819	28928759	MS	2	designed the experiment	designed the experiment	Conceived and designed the experiments	Methodology	YES
5591819	28928759	PF	2	conducted all the statistical analyses	conducted all the statistical analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5591819	28928759	SR	2	conducted all the statistical analyses	conducted all the statistical analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5591819	28928759	UV	2	designed the experiment	designed the experiment	Conceived and designed the experiments	Methodology	YES
6110306	30146662	HH	2	assisted in performing the experiments, was responsible for the radiation protection and wrote the parts of the manuscript	assisted in performing the experiments, was responsible for the radiation protection and wrote the parts of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6110306	30146662	JK	2	is the principal investigator and wrote the parts of the manuscript	is the principal investigator and wrote the parts of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Funding acquisition|Writing - Original Draft	YES
6110306	30146662	RA	2	performed the measurements and simulations and wrote the parts of the manuscript	performed the measurements and simulations and wrote the parts of the manuscript	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6110306	30146662	RF	2	designed the experiments, performed the measurements, and wrote the parts of the manuscript	designed the experiments, performed the measurements, and wrote the parts of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5374595	28361716	IT	2	designed the research and wrote the manuscript|developed the program	designed the research and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5374595	28361716	IT	2	designed the research and wrote the manuscript|developed the program	developed the program	-	Software	YES
5374595	28361716	MA	2	designed the research and wrote the manuscript	designed the research and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5374595	28361716	YT	2	developed the program	developed the program	-	Software	YES
3509394	23020856	AP	2	established relationships with the teams we worked with and presented the service in various academic and clinical forums	established relationships with the teams we worked with and presented the service in various academic and clinical forums	Performed the experiments	-	YES
3509394	23020856	All authors	2	took part in the intake of referrals, clinical meetings, training events, report writing, peer supervision|conceived of the study, participated in its design and coordination and helped to draft the manuscript|read, revised consecutive drafts, and approved the final manuscript	took part in the intake of referrals, clinical meetings, training events, report writing, peer supervision	Wrote the paper	Supervision	YES
3509394	23020856	All authors	2	took part in the intake of referrals, clinical meetings, training events, report writing, peer supervision|conceived of the study, participated in its design and coordination and helped to draft the manuscript|read, revised consecutive drafts, and approved the final manuscript	conceived of the study, participated in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
3509394	23020856	All authors	2	took part in the intake of referrals, clinical meetings, training events, report writing, peer supervision|conceived of the study, participated in its design and coordination and helped to draft the manuscript|read, revised consecutive drafts, and approved the final manuscript	read, revised consecutive drafts, and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3509394	23020856	BDJ	2	carried out the data analysis for the purpose of the service evaluation	carried out the data analysis for the purpose of the service evaluation	Analyzed the data	Formal analysis	YES
3509394	23020856	JAO	2	established relationships with the teams we worked with and presented the service in various academic and clinical forums	established relationships with the teams we worked with and presented the service in various academic and clinical forums	Performed the experiments	-	YES
3509394	23020856	KB	2	designed the toccs|established relationships with the teams we worked with and presented the service in various academic and clinical forums|provided the theoretical and methodological background to the paper and structured its content	designed the toccs	Conceived and designed the experiments	-	YES
3509394	23020856	KB	2	designed the toccs|established relationships with the teams we worked with and presented the service in various academic and clinical forums|provided the theoretical and methodological background to the paper and structured its content	established relationships with the teams we worked with and presented the service in various academic and clinical forums	Performed the experiments	-	YES
3509394	23020856	KB	2	designed the toccs|established relationships with the teams we worked with and presented the service in various academic and clinical forums|provided the theoretical and methodological background to the paper and structured its content	provided the theoretical and methodological background to the paper and structured its content	Performed the experiments	Formal analysis|Methodology	YES
4407905	25905622	CM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4407905	25905622	CT	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4407905	25905622	CT	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4407905	25905622	JAM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4407905	25905622	JAM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4407905	25905622	JAM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4407905	25905622	JAM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4407905	25905622	KFC	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4407905	25905622	KFC	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4407905	25905622	NK	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4407905	25905622	NK	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4407905	25905622	PKB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
6115317	30159638	AT	2	collected the patient data and analyzed the corresponding results	collected the patient data and analyzed the corresponding results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6115317	30159638	EK	2	collected the patient data and analyzed the corresponding results	collected the patient data and analyzed the corresponding results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6115317	30159638	KK	2	was involved in all aspects of the manuscript	was involved in all aspects of the manuscript	-	-	NO
6115317	30159638	LK	2	helped to interpret and discuss the results	helped to interpret and discuss the results	Analyzed the data	Formal analysis	YES
6115317	30159638	SH	2	helped to interpret and discuss the results	helped to interpret and discuss the results	Analyzed the data	Formal analysis	YES
5591824	28928756	DS	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5591824	28928756	EM	PLoS52	performed the simulations and analyzed the data	performed the simulations and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5591824	28928756	JB	PLoS52	performed the simulations, analyzed the data, and wrote the paper	performed the simulations, analyzed the data, and wrote the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5591824	28928756	JP	PLoS52	performed the simulations, analyzed the data, and wrote the paper	performed the simulations, analyzed the data, and wrote the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5591824	28928756	KV	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5591824	28928756	PT	PLoS52	conceived and designed the study, analyzed the data, and wrote the paper	conceived and designed the study, analyzed the data, and wrote the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
5374597	28361694	LS	PLoS52	designed the method|performed the experiments|analyzed results and wrote the manuscript	designed the method	Conceived and designed the experiments|Performed the experiments	Methodology	YES
5374597	28361694	LS	PLoS52	designed the method|performed the experiments|analyzed results and wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5374597	28361694	LS	PLoS52	designed the method|performed the experiments|analyzed results and wrote the manuscript	analyzed results and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5374597	28361694	TP	PLoS52	designed the method|analyzed results and wrote the manuscript	designed the method	Conceived and designed the experiments|Performed the experiments	Methodology	YES
5374597	28361694	TP	PLoS52	designed the method|analyzed results and wrote the manuscript	analyzed results and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4407906	25905461	AP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4407906	25905461	FS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4407906	25905461	FS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4407906	25905461	JL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4407906	25905461	JL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4407906	25905461	JL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4407906	25905461	LG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4407906	25905461	LG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4407906	25905461	LG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4407906	25905461	LG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4407906	25905461	LG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4407906	25905461	MD	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4407906	25905461	MD	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4407906	25905461	ON	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4407906	25905461	ON	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4407906	25905461	ON	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4407906	25905461	ON	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4407906	25905461	PM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4407906	25905461	PM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4407906	25905461	PM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4407906	25905461	PM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3563521	23249629	AF	2	wrote the responses to commentaries	wrote the responses to commentaries	Wrote the paper	Writing - Original Draft	YES
3563521	23249629	AH	2	wrote the commentaries	wrote the commentaries	Wrote the paper	Writing - Original Draft	YES
3563521	23249629	AM	2	wrote the commentaries	wrote the commentaries	Wrote the paper	Writing - Original Draft	YES
3563521	23249629	CP	2	wrote the commentaries	wrote the commentaries	Wrote the paper	Writing - Original Draft	YES
3563521	23249629	DP	2	wrote the commentaries	wrote the commentaries	Wrote the paper	Writing - Original Draft	YES
3563521	23249629	EM	2	wrote the commentaries	wrote the commentaries	Wrote the paper	Writing - Original Draft	YES
3563521	23249629	GG	2	wrote the commentaries	wrote the commentaries	Wrote the paper	Writing - Original Draft	YES
3563521	23249629	HD	2	wrote the commentaries	wrote the commentaries	Wrote the paper	Writing - Original Draft	YES
3563521	23249629	HP	2	wrote the commentaries	wrote the commentaries	Wrote the paper	Writing - Original Draft	YES
3563521	23249629	JC	2	wrote the commentaries	wrote the commentaries	Wrote the paper	Writing - Original Draft	YES
3563521	23249629	JParis	2	wrote the commentaries	wrote the commentaries	Wrote the paper	Writing - Original Draft	YES
3563521	23249629	JPhillips	2	wrote the general general introduction and conclusion, as well as the introductions to the individual conclusions	wrote the general general introduction and conclusion, as well as the introductions to the individual conclusions	Wrote the paper	Writing - Original Draft	YES
3563521	23249629	JW	2	wrote the commentaries	wrote the commentaries	Wrote the paper	Writing - Original Draft	YES
3563521	23249629	MC	2	wrote the commentaries	wrote the commentaries	Wrote the paper	Writing - Original Draft	YES
3563521	23249629	MF	2	wrote the commentaries	wrote the commentaries	Wrote the paper	Writing - Original Draft	YES
3563521	23249629	MS	2	wrote the commentaries	wrote the commentaries	Wrote the paper	Writing - Original Draft	YES
3563521	23249629	NG	2	wrote the commentaries	wrote the commentaries	Wrote the paper	Writing - Original Draft	YES
3563521	23249629	OW	2	wrote the commentaries	wrote the commentaries	Wrote the paper	Writing - Original Draft	YES
3563521	23249629	PZ	2	wrote the commentaries	wrote the commentaries	Wrote the paper	Writing - Original Draft	YES
3563521	23249629	RP	2	wrote the commentaries	wrote the commentaries	Wrote the paper	Writing - Original Draft	YES
3563521	23249629	SL	2	wrote the commentaries	wrote the commentaries	Wrote the paper	Writing - Original Draft	YES
3563521	23249629	SW	2	wrote the commentaries	wrote the commentaries	Wrote the paper	Writing - Original Draft	YES
3563521	23249629	TS	2	wrote the commentaries	wrote the commentaries	Wrote the paper	Writing - Original Draft	YES
3563521	23249629	WK	2	wrote the commentaries	wrote the commentaries	Wrote the paper	Writing - Original Draft	YES
6119681	30175390	DLB	PLoS52	aided results analysis and revised the manuscript	aided results analysis and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
6119681	30175390	HR	PLoS52	helped with the experiments	helped with the experiments	Performed the experiments	Investigation	YES
6119681	30175390	KPW	PLoS52	aided results analysis and revised the manuscript	aided results analysis and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
6119681	30175390	NH	PLoS52	helped with the experiments	helped with the experiments	Performed the experiments	Investigation	YES
6119681	30175390	NJF	PLoS52	helped with the experiments	helped with the experiments	Performed the experiments	Investigation	YES
6119681	30175390	RB	PLoS52	helped with the experiments	helped with the experiments	Performed the experiments	Investigation	YES
6119681	30175390	RH	PLoS52	helped with the experiments	helped with the experiments	Performed the experiments	Investigation	YES
6119681	30175390	SY	PLoS52	helped with the experiments	helped with the experiments	Performed the experiments	Investigation	YES
6119681	30175390	VMH	PLoS52	helped with the experiments	helped with the experiments	Performed the experiments	Investigation	YES
6119681	30175390	YHG	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
6119681	30175390	ZK	PLoS52	aided results analysis and revised the manuscript	aided results analysis and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5591830	28928764	AS	2	conducted the literature survey and drafted the article	conducted the literature survey and drafted the article	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5591830	28928764	BH	2	contributed additional concepts and carried out critical revision of the manuscript	contributed additional concepts and carried out critical revision of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Review & Editing	YES
5591830	28928764	CW	2	contributed additional concepts and carried out critical revision of the manuscript	contributed additional concepts and carried out critical revision of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Review & Editing	YES
5591830	28928764	KV-F	2	conceived the review|conducted the literature survey and drafted the article|wrote the manuscript	conceived the review	Conceived and designed the experiments	Conceptualization	YES
5591830	28928764	KV-F	2	conceived the review|conducted the literature survey and drafted the article|wrote the manuscript	conducted the literature survey and drafted the article	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5591830	28928764	KV-F	2	conceived the review|conducted the literature survey and drafted the article|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5591830	28928764	LH	2	contributed additional concepts and carried out critical revision of the manuscript	contributed additional concepts and carried out critical revision of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Review & Editing	YES
5591830	28928764	LQ	2	conceived the review|conducted the literature survey and drafted the article|wrote the manuscript	conceived the review	Conceived and designed the experiments	Conceptualization	YES
5591830	28928764	LQ	2	conceived the review|conducted the literature survey and drafted the article|wrote the manuscript	conducted the literature survey and drafted the article	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5591830	28928764	LQ	2	conceived the review|conducted the literature survey and drafted the article|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5591830	28928764	RS	2	conceived the review|conducted the literature survey and drafted the article	conceived the review	Conceived and designed the experiments	Conceptualization	YES
5591830	28928764	RS	2	conceived the review|conducted the literature survey and drafted the article	conducted the literature survey and drafted the article	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4407960	25906159	MF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4407960	25906159	MF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4407960	25906159	MF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4407960	25906159	WW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4407960	25906159	WW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4407960	25906159	WW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4407960	25906159	WW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4407960	25906159	WW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4823479	27110395	Both authors	2	were responsible for the study concept, design, and interpretation of data	were responsible for the study concept, design, and interpretation of data	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
4823479	27110395	Maisara Mhode	2	collected the data and performed the analysis|drafted and reviewed the paper, respectively	collected the data and performed the analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4823479	27110395	Maisara Mhode	2	collected the data and performed the analysis|drafted and reviewed the paper, respectively	drafted and reviewed the paper, respectively	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4823479	27110395	Tumaini Nyamhanga	2	drafted and reviewed the paper, respectively	drafted and reviewed the paper, respectively	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5374605	28361680	ABY	2	contributed to the framework development and analysis, participated in the analysis and simulations, and helped in reviewing the manuscript	contributed to the framework development and analysis, participated in the analysis and simulations, and helped in reviewing the manuscript	Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5374605	28361680	ES	2	provided an overall guidance, participated in the mathematical and biological interpretation of the results, and was involved in drafting the manuscript	provided an overall guidance, participated in the mathematical and biological interpretation of the results, and was involved in drafting the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Supervision|Writing - Original Draft	YES
5374605	28361680	MA	2	conceived of the study, developed the framework, conducted the analysis and simulations, provided the results interpretation and wrote the manuscript	conceived of the study, developed the framework, conducted the analysis and simulations, provided the results interpretation and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
4407961	25905793	CF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4407961	25905793	CF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4407961	25905793	CF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4407961	25905793	CF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4407961	25905793	CF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4407961	25905793	JFF	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4407961	25905793	JFF	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4407961	25905793	JFF	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4407961	25905793	PT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4407961	25905793	PT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4407961	25905793	PT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4407961	25905793	PT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4407961	25905793	RL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4407961	25905793	RL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4407961	25905793	RL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4407961	25905793	SS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4407961	25905793	SS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4407961	25905793	SS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6141406	30225675	All authors	2	critically reviewed the manuscript and were involved in the study design	critically reviewed the manuscript and were involved in the study design	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
6141406	30225675	EP	2	performed the data acquisition and analysis and provided input to the manuscript	performed the data acquisition and analysis and provided input to the manuscript	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6141406	30225675	FvV	2	implemented the simulation tool	implemented the simulation tool	Performed the experiments	Formal analysis|Investigation	YES
6141406	30225675	JdJ	2	performed the data acquisition and analysis and provided input to the manuscript	performed the data acquisition and analysis and provided input to the manuscript	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6141406	30225675	RB	2	performed the data acquisition and analysis and provided input to the manuscript|implemented the simulation tool|supervised the project	performed the data acquisition and analysis and provided input to the manuscript	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6141406	30225675	RB	2	performed the data acquisition and analysis and provided input to the manuscript|implemented the simulation tool|supervised the project	implemented the simulation tool	Performed the experiments	Formal analysis|Investigation	YES
6141406	30225675	RB	2	performed the data acquisition and analysis and provided input to the manuscript|implemented the simulation tool|supervised the project	supervised the project	-	Supervision	YES
6141406	30225675	RD	2	supervised the project	supervised the project	-	Supervision	YES
3599877	23433035	All authors	2	planned and elucidated the layout	planned and elucidated the layout	Conceived and designed the experiments	Conceptualization	YES
4298783	23901045	A.M.J.	2	designed the research|performed the research and collected the data|analyzed and interpreted the data|wrote the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
4298783	23901045	A.M.J.	2	designed the research|performed the research and collected the data|analyzed and interpreted the data|wrote the manuscript	performed the research and collected the data	Performed the experiments	Investigation	YES
4298783	23901045	A.M.J.	2	designed the research|performed the research and collected the data|analyzed and interpreted the data|wrote the manuscript	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
4298783	23901045	A.M.J.	2	designed the research|performed the research and collected the data|analyzed and interpreted the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4298783	23901045	D.E.	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4298783	23901045	H.A.F.	2	designed the research|performed the research and collected the data|analyzed and interpreted the data|performed statistical analysis|wrote the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
4298783	23901045	H.A.F.	2	designed the research|performed the research and collected the data|analyzed and interpreted the data|performed statistical analysis|wrote the manuscript	performed the research and collected the data	Performed the experiments	Investigation	YES
4298783	23901045	H.A.F.	2	designed the research|performed the research and collected the data|analyzed and interpreted the data|performed statistical analysis|wrote the manuscript	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
4298783	23901045	H.A.F.	2	designed the research|performed the research and collected the data|analyzed and interpreted the data|performed statistical analysis|wrote the manuscript	performed statistical analysis	Analyzed the data	Formal analysis	YES
4298783	23901045	H.A.F.	2	designed the research|performed the research and collected the data|analyzed and interpreted the data|performed statistical analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4298783	23901045	M.K.C.	2	designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
4298783	23901045	P.M.P.	2	designed the research|analyzed and interpreted the data|wrote the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
4298783	23901045	P.M.P.	2	designed the research|analyzed and interpreted the data|wrote the manuscript	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
4298783	23901045	P.M.P.	2	designed the research|analyzed and interpreted the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4298783	23901045	Q.W.	2	performed the research and collected the data	performed the research and collected the data	Performed the experiments	Investigation	YES
4298783	23901045	S.J.F.	2	performed the research and collected the data	performed the research and collected the data	Performed the experiments	Investigation	YES
5591835	28928753	AE	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5591835	28928753	All authors	PLoS52	analyzed the data, read and approved the manuscript	analyzed the data, read and approved the manuscript	Analyzed the data	Formal analysis	YES
5591835	28928753	DF	PLoS52	designed the project and the experiments	designed the project and the experiments	Conceived and designed the experiments	Methodology	YES
5591835	28928753	HR	PLoS52	designed the project and the experiments	designed the project and the experiments	Conceived and designed the experiments	Methodology	YES
5591835	28928753	SO	PLoS52	designed the project and the experiments	designed the project and the experiments	Conceived and designed the experiments	Methodology	YES
3620706	23531271	AS	1	Data analysis and interpretation|Critical revision of the article for important intellectual content	Data analysis and interpretation	Analyzed the data	Formal analysis	YES
3620706	23531271	AS	1	Data analysis and interpretation|Critical revision of the article for important intellectual content	Critical revision of the article for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
3620706	23531271	AdH	1	Data analysis and interpretation|Drafting of the article	Data analysis and interpretation	Analyzed the data	Formal analysis	YES
3620706	23531271	AdH	1	Data analysis and interpretation|Drafting of the article	Drafting of the article	Wrote the paper	Writing - Original Draft	YES
3620706	23531271	AdeH	1	Critical revision of the article for important intellectual content	Critical revision of the article for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
3620706	23531271	CC	1	Collection and assembly of the data|Data analysis and interpretation|Data analysis and interpretation|Critical revision of the article for important intellectual content	Collection and assembly of the data	Performed the experiments	Investigation	YES
3620706	23531271	CC	1	Collection and assembly of the data|Data analysis and interpretation|Data analysis and interpretation|Critical revision of the article for important intellectual content	Data analysis and interpretation	Analyzed the data	Formal analysis	YES
3620706	23531271	CC	1	Collection and assembly of the data|Data analysis and interpretation|Data analysis and interpretation|Critical revision of the article for important intellectual content	Data analysis and interpretation	Analyzed the data	Formal analysis	YES
3620706	23531271	CC	1	Collection and assembly of the data|Data analysis and interpretation|Data analysis and interpretation|Critical revision of the article for important intellectual content	Critical revision of the article for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
3620706	23531271	CMO	1	Data analysis and interpretation|Critical revision of the article for important intellectual content	Data analysis and interpretation	Analyzed the data	Formal analysis	YES
3620706	23531271	CMO	1	Data analysis and interpretation|Critical revision of the article for important intellectual content	Critical revision of the article for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
3620706	23531271	DB	1	Critical revision of the article for important intellectual content	Critical revision of the article for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
3620706	23531271	HC	1	Critical revision of the article for important intellectual content	Critical revision of the article for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
3620706	23531271	JM	1	Collection and assembly of the data|Data analysis and interpretation|Critical revision of the article for important intellectual content	Collection and assembly of the data	Performed the experiments	Investigation	YES
3620706	23531271	JM	1	Collection and assembly of the data|Data analysis and interpretation|Critical revision of the article for important intellectual content	Data analysis and interpretation	Analyzed the data	Formal analysis	YES
3620706	23531271	JM	1	Collection and assembly of the data|Data analysis and interpretation|Critical revision of the article for important intellectual content	Critical revision of the article for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
3620706	23531271	MMA	1	Drafting of the article	Drafting of the article	Wrote the paper	Writing - Original Draft	YES
3620706	23531271	MMAB	1	Conception and design|Collection and assembly of the data|Data analysis and interpretation|Critical revision of the article for important intellectual content|Obtaining of funding	Conception and design	Conceived and designed the experiments	Conceptualization	YES
3620706	23531271	MMAB	1	Conception and design|Collection and assembly of the data|Data analysis and interpretation|Critical revision of the article for important intellectual content|Obtaining of funding	Collection and assembly of the data	Performed the experiments	Investigation	YES
3620706	23531271	MMAB	1	Conception and design|Collection and assembly of the data|Data analysis and interpretation|Critical revision of the article for important intellectual content|Obtaining of funding	Data analysis and interpretation	Analyzed the data	Formal analysis	YES
3620706	23531271	MMAB	1	Conception and design|Collection and assembly of the data|Data analysis and interpretation|Critical revision of the article for important intellectual content|Obtaining of funding	Critical revision of the article for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
3620706	23531271	MMAB	1	Conception and design|Collection and assembly of the data|Data analysis and interpretation|Critical revision of the article for important intellectual content|Obtaining of funding	Obtaining of funding	-	Funding acquisition	YES
3620706	23531271	NAB	1	Conception and design|Data analysis and interpretation|Drafting of the article|Critical revision of the article for important intellectual content	Conception and design	Conceived and designed the experiments	Conceptualization	YES
3620706	23531271	NAB	1	Conception and design|Data analysis and interpretation|Drafting of the article|Critical revision of the article for important intellectual content	Data analysis and interpretation	Analyzed the data	Formal analysis	YES
3620706	23531271	NAB	1	Conception and design|Data analysis and interpretation|Drafting of the article|Critical revision of the article for important intellectual content	Drafting of the article	Wrote the paper	Writing - Original Draft	YES
3620706	23531271	NAB	1	Conception and design|Data analysis and interpretation|Drafting of the article|Critical revision of the article for important intellectual content	Critical revision of the article for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
3620706	23531271	RND	1	Collection and assembly of the data|Data analysis and interpretation|Drafting of the article|Critical revision of the article for important intellectual content	Collection and assembly of the data	Performed the experiments	Investigation	YES
3620706	23531271	RND	1	Collection and assembly of the data|Data analysis and interpretation|Drafting of the article|Critical revision of the article for important intellectual content	Data analysis and interpretation	Analyzed the data	Formal analysis	YES
3620706	23531271	RND	1	Collection and assembly of the data|Data analysis and interpretation|Drafting of the article|Critical revision of the article for important intellectual content	Drafting of the article	Wrote the paper	Writing - Original Draft	YES
3620706	23531271	RND	1	Collection and assembly of the data|Data analysis and interpretation|Drafting of the article|Critical revision of the article for important intellectual content	Critical revision of the article for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
3620706	23531271	SR	1	Collection and assembly of the data|Data analysis and interpretation|Critical revision of the article for important intellectual content	Collection and assembly of the data	Performed the experiments	Investigation	YES
3620706	23531271	SR	1	Collection and assembly of the data|Data analysis and interpretation|Critical revision of the article for important intellectual content	Data analysis and interpretation	Analyzed the data	Formal analysis	YES
3620706	23531271	SR	1	Collection and assembly of the data|Data analysis and interpretation|Critical revision of the article for important intellectual content	Critical revision of the article for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
3620706	23531271	all authors	1	Final approval of the article	Final approval of the article	-	-	NO
5515040	28691442	ATC	1	Grant holder|Conceived of the study|Provided input in the design of the study|Recruited participants and managed study data|Conducting data analysis	Grant holder	-	Funding acquisition	YES
5515040	28691442	ATC	1	Grant holder|Conceived of the study|Provided input in the design of the study|Recruited participants and managed study data|Conducting data analysis	Conceived of the study	Conceived and designed the experiments	Conceptualization	YES
5515040	28691442	ATC	1	Grant holder|Conceived of the study|Provided input in the design of the study|Recruited participants and managed study data|Conducting data analysis	Provided input in the design of the study	Conceived and designed the experiments	Methodology	YES
5515040	28691442	ATC	1	Grant holder|Conceived of the study|Provided input in the design of the study|Recruited participants and managed study data|Conducting data analysis	Recruited participants and managed study data	Performed the experiments|Analyzed the data	Data curation|Investigation|Project administration	YES
5515040	28691442	ATC	1	Grant holder|Conceived of the study|Provided input in the design of the study|Recruited participants and managed study data|Conducting data analysis	Conducting data analysis	Analyzed the data	Formal analysis	YES
5515040	28691442	DWS	1	Recruited participants and managed study data|Conducting data analysis	Recruited participants and managed study data	Performed the experiments|Analyzed the data	Data curation|Investigation|Project administration	YES
5515040	28691442	DWS	1	Recruited participants and managed study data|Conducting data analysis	Conducting data analysis	Analyzed the data	Formal analysis	YES
5515040	28691442	ELC	1	Conceived of the study|Provided input in the design of the study	Conceived of the study	Conceived and designed the experiments	Conceptualization	YES
5515040	28691442	ELC	1	Conceived of the study|Provided input in the design of the study	Provided input in the design of the study	Conceived and designed the experiments	Methodology	YES
5515040	28691442	JC	1	Provided input in the design of the study	Provided input in the design of the study	Conceived and designed the experiments	Methodology	YES
5515040	28691442	KF	1	Provided input in the design of the study	Provided input in the design of the study	Conceived and designed the experiments	Methodology	YES
5515040	28691442	MCC	1	Conducting data analysis	Conducting data analysis	Analyzed the data	Formal analysis	YES
5515040	28691442	MKK	1	Provided input in the design of the study|Recruited participants and managed study data|Conducting data analysis	Provided input in the design of the study	Conceived and designed the experiments	Methodology	YES
5515040	28691442	MKK	1	Provided input in the design of the study|Recruited participants and managed study data|Conducting data analysis	Recruited participants and managed study data	Performed the experiments|Analyzed the data	Data curation|Investigation|Project administration	YES
5515040	28691442	MKK	1	Provided input in the design of the study|Recruited participants and managed study data|Conducting data analysis	Conducting data analysis	Analyzed the data	Formal analysis	YES
5515040	28691442	ND	1	Provided input in the design of the study|Provided input in the design of the study	Provided input in the design of the study	Conceived and designed the experiments	Methodology	YES
5515040	28691442	ND	1	Provided input in the design of the study|Provided input in the design of the study	Provided input in the design of the study	Conceived and designed the experiments	Methodology	YES
4407962	25906317	AE	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4407962	25906317	AE	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4407962	25906317	KG	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4407962	25906317	KG	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4407962	25906317	KG	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4407962	25906317	KG	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4407962	25906317	LL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4407962	25906317	LL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4407962	25906317	LL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4407962	25906317	SG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4407962	25906317	SG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4407962	25906317	SG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4407962	25906317	SG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4407962	25906317	SG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4407962	25906317	WAW	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4407962	25906317	WAW	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4407962	25906317	YG	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5591845	28928755	AW	2	contributed in conducting the experiments	contributed in conducting the experiments	Performed the experiments	Investigation	YES
5591845	28928755	HF	2	supervised the study and experiment, and contributed in the evaluation of manuscript	supervised the study and experiment, and contributed in the evaluation of manuscript	-	Supervision	YES
5591845	28928755	VS	2	carried out all the experiments, analyzed the datas, and write the manuscript	carried out all the experiments, analyzed the datas, and write the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6156690	30255439	GKvS	2	gave technical support and conceptual advice	gave technical support and conceptual advice	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
6156690	30255439	IAB	2	gave technical support and conceptual advice	gave technical support and conceptual advice	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
6156690	30255439	JT	2	collected the data	collected the data	Performed the experiments	Investigation	YES
6156690	30255439	MES	2	collected the data	collected the data	Performed the experiments	Investigation	YES
6156690	30255439	MM	2	designed the study and prepared the manuscript|collected the data|did the statistical analysis	designed the study and prepared the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
6156690	30255439	MM	2	designed the study and prepared the manuscript|collected the data|did the statistical analysis	collected the data	Performed the experiments	Investigation	YES
6156690	30255439	MM	2	designed the study and prepared the manuscript|collected the data|did the statistical analysis	did the statistical analysis	Analyzed the data	Formal analysis	YES
6156690	30255439	MWH	2	designed the study and prepared the manuscript|did the statistical analysis	designed the study and prepared the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
6156690	30255439	MWH	2	designed the study and prepared the manuscript|did the statistical analysis	did the statistical analysis	Analyzed the data	Formal analysis	YES
6156690	30255439	PAK	2	gave technical support and conceptual advice	gave technical support and conceptual advice	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
6156690	30255439	PS	2	collected the data|did the statistical analysis	collected the data	Performed the experiments	Investigation	YES
6156690	30255439	PS	2	collected the data|did the statistical analysis	did the statistical analysis	Analyzed the data	Formal analysis	YES
6156690	30255439	SDA	2	gave technical support and conceptual advice	gave technical support and conceptual advice	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
6174116	30294746	CH	2	aided in the data acquisition and urine sample analysis|contributed to the imaging and urine count protocol development as well as manuscript revision	aided in the data acquisition and urine sample analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6174116	30294746	CH	2	aided in the data acquisition and urine sample analysis|contributed to the imaging and urine count protocol development as well as manuscript revision	contributed to the imaging and urine count protocol development as well as manuscript revision	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Methodology|Visualization|Writing - Original Draft|Writing - Review & Editing	YES
6174116	30294746	ES	2	contributed to the imaging and urine count protocol development as well as manuscript revision	contributed to the imaging and urine count protocol development as well as manuscript revision	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Methodology|Visualization|Writing - Original Draft|Writing - Review & Editing	YES
6174116	30294746	HL	2	contributed to the imaging and urine count protocol development as well as manuscript revision	contributed to the imaging and urine count protocol development as well as manuscript revision	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Methodology|Visualization|Writing - Original Draft|Writing - Review & Editing	YES
6174116	30294746	JC	2	performed the research coordination and clinical data collection	performed the research coordination and clinical data collection	Performed the experiments	Investigation|Project administration	YES
6174116	30294746	JS	2	is a certified medical physicist who aided in the imaging protocol development, radioactive dosimetry calculations, and revision of manuscript	is a certified medical physicist who aided in the imaging protocol development, radioactive dosimetry calculations, and revision of manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Visualization|Writing - Original Draft|Writing - Review & Editing	YES
6174116	30294746	KL	2	analyzed and interpreted data and assisted in drafting the manuscript	analyzed and interpreted data and assisted in drafting the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6174116	30294746	RD	2	participated in study design, data acquisition, analysis, and interpretation and drafted the manuscript	participated in study design, data acquisition, analysis, and interpretation and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
6174116	30294746	RM	2	as senior author helped in all areas	as senior author helped in all areas	-	-	NO
6174116	30294746	RS	2	assisted in the protocol development and data acquisition	assisted in the protocol development and data acquisition	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6174116	30294746	SL	2	aided in the data acquisition and urine sample analysis	aided in the data acquisition and urine sample analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5374636	28361698	LH	2	performed the computational tasks	performed the computational tasks	Performed the experiments	Formal analysis|Investigation	YES
5374636	28361698	NH	2	performed the computational tasks|drafted the manuscript	performed the computational tasks	Performed the experiments	Formal analysis|Investigation	YES
5374636	28361698	NH	2	performed the computational tasks|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5374636	28361698	WK	2	analyzed the results	analyzed the results	Analyzed the data	Formal analysis	YES
5374636	28361698	YY	2	designed the system|analyzed the results|drafted the manuscript	designed the system	Conceived and designed the experiments	-	YES
5374636	28361698	YY	2	designed the system|analyzed the results|drafted the manuscript	analyzed the results	Analyzed the data	Formal analysis	YES
5374636	28361698	YY	2	designed the system|analyzed the results|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4407964	25905908	AD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4407964	25905908	AD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4407964	25905908	AD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4407964	25905908	AD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4407964	25905908	AD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4407964	25905908	AMC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4407964	25905908	AMC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4407964	25905908	AMC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4407964	25905908	ATLQ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4407964	25905908	ATLQ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4407964	25905908	ATLQ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4407964	25905908	ATLQ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4407964	25905908	ATLQ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4407964	25905908	CHB	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4407964	25905908	CHB	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4407964	25905908	CIO	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4407964	25905908	CIO	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4407964	25905908	CIO	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4407964	25905908	CIO	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4407964	25905908	MB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4407964	25905908	MB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4407964	25905908	MB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4407964	25905908	MBN	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4407964	25905908	MBN	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4407964	25905908	MBN	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4407964	25905908	RT	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4407964	25905908	RT	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5591850	28928763	All authors	2	read and approved of the final manuscript	read and approved of the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5591850	28928763	BG	2	managed the field experiments	managed the field experiments	Performed the experiments	Investigation	YES
5591850	28928763	CL	2	managed the field experiments	managed the field experiments	Performed the experiments	Investigation	YES
5591850	28928763	JZ	2	measured the grain amylopectin content, performed qtl, gwas and candidate gene analysis, and wrote the manuscript	measured the grain amylopectin content, performed qtl, gwas and candidate gene analysis, and wrote the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5591850	28928763	RX	2	supervised the project	supervised the project	-	Supervision	YES
5591850	28928763	WD	2	prepared the grain flour for amylopectin content measurement and prepared the dna and rna of materials for relevant experiment	prepared the grain flour for amylopectin content measurement and prepared the dna and rna of materials for relevant experiment	Performed the experiments	Investigation	YES
5591850	28928763	XF	2	measured the grain amylopectin content, performed qtl, gwas and candidate gene analysis, and wrote the manuscript	measured the grain amylopectin content, performed qtl, gwas and candidate gene analysis, and wrote the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5591850	28928763	YS	2	prepared the grain flour for amylopectin content measurement and prepared the dna and rna of materials for relevant experiment	prepared the grain flour for amylopectin content measurement and prepared the dna and rna of materials for relevant experiment	Performed the experiments	Investigation	YES
6186532	30318563	AC	2	participated in the design of the analysis and contributed to the manuscript editing	participated in the design of the analysis and contributed to the manuscript editing	Conceived and designed the experiments|Wrote the paper	Writing - Review & Editing	YES
6186532	30318563	FA	2	performed dosimetry analyses	performed dosimetry analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6186532	30318563	FAB	2	were responsible for the good conduct of the clinical study and data acquisition	were responsible for the good conduct of the clinical study and data acquisition	Performed the experiments	Investigation	YES
6186532	30318563	JMB	2	were responsible for the good conduct of the clinical study and data acquisition|designed the analysis, supervised the project, analyzed the data, and edited the manuscript	were responsible for the good conduct of the clinical study and data acquisition	Performed the experiments	Investigation	YES
6186532	30318563	JMB	2	were responsible for the good conduct of the clinical study and data acquisition|designed the analysis, supervised the project, analyzed the data, and edited the manuscript	designed the analysis, supervised the project, analyzed the data, and edited the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Supervision|Writing - Review & Editing	YES
6186532	30318563	MDP	2	participated in the design of the analysis, collected and analyzed the data, and drafted the manuscript	participated in the design of the analysis, collected and analyzed the data, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6186532	30318563	NS	2	performed dosimetry analyses	performed dosimetry analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6186532	30318563	WZ	2	participated in the design of the analysis and contributed to the manuscript editing	participated in the design of the analysis and contributed to the manuscript editing	Conceived and designed the experiments|Wrote the paper	Writing - Review & Editing	YES
3717278	23866101	JEM	2	wrote and edited the manuscript	wrote and edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3717278	23866101	SJM	2	researched, wrote, and edited the manuscript	researched, wrote, and edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3717278	23866101	TJP	2	conceived, researched, wrote, and edited the manuscript	conceived, researched, wrote, and edited the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
3132863	21754972	HB	PLoS52	conceived the study|cared for patients|wrote the paper	conceived the study	Conceived and designed the experiments	Conceptualization	YES
3132863	21754972	HB	PLoS52	conceived the study|cared for patients|wrote the paper	cared for patients	Performed the experiments	Investigation	YES
3132863	21754972	HB	PLoS52	conceived the study|cared for patients|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3132863	21754972	JS	PLoS52	conceived the study|cared for patients|wrote the paper	conceived the study	Conceived and designed the experiments	Conceptualization	YES
3132863	21754972	JS	PLoS52	conceived the study|cared for patients|wrote the paper	cared for patients	Performed the experiments	Investigation	YES
3132863	21754972	JS	PLoS52	conceived the study|cared for patients|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3132863	21754972	LLL	PLoS52	cared for patients	cared for patients	Performed the experiments	Investigation	YES
3132863	21754972	SKD	PLoS52	conceived the study|wrote the paper	conceived the study	Conceived and designed the experiments	Conceptualization	YES
3132863	21754972	SKD	PLoS52	conceived the study|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3132863	21754972	SS	PLoS52	conceived the study|wrote the paper	conceived the study	Conceived and designed the experiments	Conceptualization	YES
3132863	21754972	SS	PLoS52	conceived the study|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3723553	23866073	EJA	2	worked on the euho simulation|reviewed the first draft	worked on the euho simulation	Performed the experiments	Formal analysis	YES
3723553	23866073	EJA	2	worked on the euho simulation|reviewed the first draft	reviewed the first draft	Wrote the paper	Writing - Original Draft	YES
3723553	23866073	JRF	2	worked on the euho simulation|wrote the first draft	worked on the euho simulation	Performed the experiments	Formal analysis	YES
3723553	23866073	JRF	2	worked on the euho simulation|wrote the first draft	wrote the first draft	Wrote the paper	Writing - Original Draft	YES
3723553	23866073	KC	2	worked on the monwho simulation|reviewed the first draft	worked on the monwho simulation	Performed the experiments	Formal analysis	YES
3723553	23866073	KC	2	worked on the monwho simulation|reviewed the first draft	reviewed the first draft	Wrote the paper	Writing - Original Draft	YES
3723553	23866073	PGR	2	worked on the euho simulation|reviewed the first draft	worked on the euho simulation	Performed the experiments	Formal analysis	YES
3723553	23866073	PGR	2	worked on the euho simulation|reviewed the first draft	reviewed the first draft	Wrote the paper	Writing - Original Draft	YES
3723553	23866073	SF	2	worked on the monwho simulation|reviewed the first draft	worked on the monwho simulation	Performed the experiments	Formal analysis	YES
3723553	23866073	SF	2	worked on the monwho simulation|reviewed the first draft	reviewed the first draft	Wrote the paper	Writing - Original Draft	YES
4963552	27493798	Amarech Asratie Wubante	2	analyzed the data and helped to draft the paper	analyzed the data and helped to draft the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4963552	27493798	Amtatachew Moges Zegeye	2	analyzed the data and helped to draft the paper	analyzed the data and helped to draft the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4963552	27493798	Ketema Tafess Tulu	2	analyzed the data and helped to draft the paper	analyzed the data and helped to draft the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4963552	27493798	Melashu Balew Shiferaw	2	participated in the design of the study and data collection, performed the statistical analysis, and drafted the paper	participated in the design of the study and data collection, performed the statistical analysis, and drafted the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5374647	28361690	JP	2	implemented the nhdp program for this project	implemented the nhdp program for this project	Performed the experiments	Investigation	YES
5374647	28361690	VC	2	carried out all the data collection, modeling and analyses	carried out all the data collection, modeling and analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5374647	28361690	XL	2	conceived the project	conceived the project	Conceived and designed the experiments	Conceptualization	YES
3750377	23902732	BD	2	worked to improve the clinical aspects of the paper|all read the first version and contributed editorial and critical suggestions	worked to improve the clinical aspects of the paper	Performed the experiments|Wrote the paper	Writing - Review & Editing	YES
3750377	23902732	BD	2	worked to improve the clinical aspects of the paper|all read the first version and contributed editorial and critical suggestions	all read the first version and contributed editorial and critical suggestions	-	-	NO
3750377	23902732	JA	2	originated the article, did the research and wrote a first rough draft of the manuscript|all read the first version and contributed editorial and critical suggestions|made substantial revisions to the earlier draft and worked toward the final draft|have all read and approved the final version of the manuscript	originated the article, did the research and wrote a first rough draft of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
3750377	23902732	JA	2	originated the article, did the research and wrote a first rough draft of the manuscript|all read the first version and contributed editorial and critical suggestions|made substantial revisions to the earlier draft and worked toward the final draft|have all read and approved the final version of the manuscript	all read the first version and contributed editorial and critical suggestions	-	-	NO
3750377	23902732	JA	2	originated the article, did the research and wrote a first rough draft of the manuscript|all read the first version and contributed editorial and critical suggestions|made substantial revisions to the earlier draft and worked toward the final draft|have all read and approved the final version of the manuscript	made substantial revisions to the earlier draft and worked toward the final draft	Performed the experiments|Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3750377	23902732	JA	2	originated the article, did the research and wrote a first rough draft of the manuscript|all read the first version and contributed editorial and critical suggestions|made substantial revisions to the earlier draft and worked toward the final draft|have all read and approved the final version of the manuscript	have all read and approved the final version of the manuscript	-	-	NO
6196145	30345471	DN	2	were responsible for the patient recruitment and critically evaluated the manuscript	were responsible for the patient recruitment and critically evaluated the manuscript	Performed the experiments	Investigation	YES
6196145	30345471	EML	2	contributed to the study design and critical evaluation of the manuscript	contributed to the study design and critical evaluation of the manuscript	Conceived and designed the experiments	Methodology	YES
6196145	30345471	HA	2	contributed to the study design and critical evaluation of the manuscript	contributed to the study design and critical evaluation of the manuscript	Conceived and designed the experiments	Methodology	YES
6196145	30345471	JMS	2	performed the reconstructions, built the imaging analysis pipeline, analysed the data and drafted the manuscript	performed the reconstructions, built the imaging analysis pipeline, analysed the data and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Visualization|Writing - Original Draft	YES
6196145	30345471	LA	2	designed the study and contributed to the data analysis and drafting of the manuscript	designed the study and contributed to the data analysis and drafting of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
6196145	30345471	ME	2	provided assistance in the construction of the image analysis pipeline and reconstructions and critically evaluated the manuscript	provided assistance in the construction of the image analysis pipeline and reconstructions and critically evaluated the manuscript	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
6196145	30345471	ML	2	designed the study and contributed to the data analysis and drafting of the manuscript	designed the study and contributed to the data analysis and drafting of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
6196145	30345471	SP	2	were responsible for the patient recruitment and critically evaluated the manuscript	were responsible for the patient recruitment and critically evaluated the manuscript	Performed the experiments	Investigation	YES
5591867	28928754	GA	2	conceived the idea and designed the outlines of the article|wrote the article|revised the article	conceived the idea and designed the outlines of the article	Conceived and designed the experiments	Conceptualization	YES
5591867	28928754	GA	2	conceived the idea and designed the outlines of the article|wrote the article|revised the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
5591867	28928754	GA	2	conceived the idea and designed the outlines of the article|wrote the article|revised the article	revised the article	Wrote the paper	Writing - Review & Editing	YES
5591867	28928754	MH	2	conceived the idea and designed the outlines of the article|wrote the article	conceived the idea and designed the outlines of the article	Conceived and designed the experiments	Conceptualization	YES
5591867	28928754	MH	2	conceived the idea and designed the outlines of the article|wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
5591867	28928754	MK	2	wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
5591867	28928754	XC	2	revised the article	revised the article	Wrote the paper	Writing - Review & Editing	YES
5591867	28928754	YC	2	wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
5591867	28928754	ZQ	2	revised the article	revised the article	Wrote the paper	Writing - Review & Editing	YES
4407983	25906243	HSRC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4407983	25906243	HSRC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4407983	25906243	HSRC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4407983	25906243	JDB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4407983	25906243	JDB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4407983	25906243	JDB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4407983	25906243	JDB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4407983	25906243	PDM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4407983	25906243	PDM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4407983	25906243	PDM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5374651	28361681	All of the authors	PLoS52	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5374651	28361681	HHH	PLoS52	wrote this manuscript|prepared the figures|analyzed the data	wrote this manuscript	Wrote the paper	Writing - Original Draft	YES
5374651	28361681	HHH	PLoS52	wrote this manuscript|prepared the figures|analyzed the data	prepared the figures	-	Visualization	YES
5374651	28361681	HHH	PLoS52	wrote this manuscript|prepared the figures|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5374651	28361681	JMY	PLoS52	designed and supervised this study|wrote this manuscript|prepared the figures|analyzed the data	designed and supervised this study	Conceived and designed the experiments	Methodology|Supervision	YES
5374651	28361681	JMY	PLoS52	designed and supervised this study|wrote this manuscript|prepared the figures|analyzed the data	wrote this manuscript	Wrote the paper	Writing - Original Draft	YES
5374651	28361681	JMY	PLoS52	designed and supervised this study|wrote this manuscript|prepared the figures|analyzed the data	prepared the figures	-	Visualization	YES
5374651	28361681	JMY	PLoS52	designed and supervised this study|wrote this manuscript|prepared the figures|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5374651	28361681	LJC	PLoS52	prepared the figures|analyzed the data	prepared the figures	-	Visualization	YES
5374651	28361681	LJC	PLoS52	prepared the figures|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5374651	28361681	YCH	PLoS52	prepared the figures|analyzed the data	prepared the figures	-	Visualization	YES
5374651	28361681	YCH	PLoS52	prepared the figures|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5591876	28928765	AM	2	developed the initial concept and outline and they took lead in expanding the content	developed the initial concept and outline and they took lead in expanding the content	Conceived and designed the experiments	Conceptualization	YES
5591876	28928765	BC	2	developed the initial concept and outline and they took lead in expanding the content	developed the initial concept and outline and they took lead in expanding the content	Conceived and designed the experiments	Conceptualization	YES
5591876	28928765	FA	2	contributed and edited the manuscript	contributed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5591876	28928765	GM	2	developed the initial concept and outline and they took lead in expanding the content	developed the initial concept and outline and they took lead in expanding the content	Conceived and designed the experiments	Conceptualization	YES
5591876	28928765	PJ	2	contributed and edited the manuscript	contributed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5591876	28928765	SF	2	contributed and edited the manuscript	contributed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
6212377	30386924	AJATB	2	has provided written text as well as clinical examples	has provided written text as well as clinical examples	Wrote the paper	Writing - Original Draft	YES
6212377	30386924	BK	2	has written a section of the manuscript	has written a section of the manuscript	Wrote the paper	Writing - Original Draft	YES
6212377	30386924	HWAMdJ	2	designed the initial outline of the manuscript	designed the initial outline of the manuscript	Conceived and designed the experiments	-	YES
6212377	30386924	MGEHL	2	designed the initial outline of the manuscript	designed the initial outline of the manuscript	Conceived and designed the experiments	-	YES
6212377	30386924	RB	2	drafted the manuscript with input from all authors	drafted the manuscript with input from all authors	Wrote the paper	Writing - Original Draft	YES
6212377	30386924	SCK	2	designed the initial outline of the manuscript	designed the initial outline of the manuscript	Conceived and designed the experiments	-	YES
5374653	28359302	DT	2	participated in the design of the experiments, data analysis and writing the manuscript|performed the bioinformatics analysis	participated in the design of the experiments, data analysis and writing the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5374653	28359302	DT	2	participated in the design of the experiments, data analysis and writing the manuscript|performed the bioinformatics analysis	performed the bioinformatics analysis	Performed the experiments	Formal analysis|Investigation	YES
5374653	28359302	TD	2	participated in the design of the experiments, data analysis and writing the manuscript|performed the bioinformatics analysis	participated in the design of the experiments, data analysis and writing the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5374653	28359302	TD	2	participated in the design of the experiments, data analysis and writing the manuscript|performed the bioinformatics analysis	performed the bioinformatics analysis	Performed the experiments	Formal analysis|Investigation	YES
5374653	28359302	UK	2	participated in the design of the experiments, data analysis and writing the manuscript|coordinated the project and edited the manuscript	participated in the design of the experiments, data analysis and writing the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5374653	28359302	UK	2	participated in the design of the experiments, data analysis and writing the manuscript|coordinated the project and edited the manuscript	coordinated the project and edited the manuscript	Wrote the paper	Project administration|Writing - Review & Editing	YES
4407985	25906147	GVD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4407985	25906147	GVD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4407985	25906147	GVD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4407985	25906147	HV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4407985	25906147	HV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4407985	25906147	HV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4407985	25906147	HV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4407985	25906147	JC	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4407985	25906147	LW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4407985	25906147	LW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4407985	25906147	LW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4407985	25906147	LW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4407985	25906147	RS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4407985	25906147	RS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4407985	25906147	RS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4529887	26273590	Alessandra Cassoni	2	were in charge of the laboratory processing of the samples and participated in the data analyses and elaboration of the paper	were in charge of the laboratory processing of the samples and participated in the data analyses and elaboration of the paper	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
4529887	26273590	Claudia Ota-Tsuzuki	2	were in charge of the elaboration of the study proposal and the financial support of the study, and they participated in the elaboration of the paper|were in charge of the laboratory processing of the samples and participated in the data analyses and elaboration of the paper	were in charge of the elaboration of the study proposal and the financial support of the study, and they participated in the elaboration of the paper	-	Funding acquisition	YES
4529887	26273590	Claudia Ota-Tsuzuki	2	were in charge of the elaboration of the study proposal and the financial support of the study, and they participated in the elaboration of the paper|were in charge of the laboratory processing of the samples and participated in the data analyses and elaboration of the paper	were in charge of the laboratory processing of the samples and participated in the data analyses and elaboration of the paper	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
4529887	26273590	Cristiane Goncalves	2	were in charge of the saliva collection, laboratory processing, and oral biofilm maintenance and they participated in the elaboration of the paper	were in charge of the saliva collection, laboratory processing, and oral biofilm maintenance and they participated in the elaboration of the paper	-	-	NO
4529887	26273590	Elton G. Zenobio	2	were in charge of the statistical analysis, the implant surface characterization, and the financial support for the study	were in charge of the statistical analysis, the implant surface characterization, and the financial support for the study	Performed the experiments|Analyzed the data	Formal analysis|Funding acquisition|Investigation	YES
4529887	26273590	Gabriela Giro	2	were in charge of the saliva collection, laboratory processing, and oral biofilm maintenance and they participated in the elaboration of the paper	were in charge of the saliva collection, laboratory processing, and oral biofilm maintenance and they participated in the elaboration of the paper	-	-	NO
4529887	26273590	Jamil Awad Shibli	2	were in charge of the elaboration of the study proposal and the financial support of the study, and they participated in the elaboration of the paper	were in charge of the elaboration of the study proposal and the financial support of the study, and they participated in the elaboration of the paper	-	Funding acquisition	YES
4529887	26273590	Jose Augusto Rodrigues	2	were in charge of the elaboration of the study proposal and the financial support of the study, and they participated in the elaboration of the paper	were in charge of the elaboration of the study proposal and the financial support of the study, and they participated in the elaboration of the paper	-	Funding acquisition	YES
4529887	26273590	Luciene C. Figueiredo	2	were in charge of the statistical analysis, the implant surface characterization, and the financial support for the study	were in charge of the statistical analysis, the implant surface characterization, and the financial support for the study	Performed the experiments|Analyzed the data	Formal analysis|Funding acquisition|Investigation	YES
4529887	26273590	Pedro Paulo Cardoso	2	were in charge of the saliva collection, laboratory processing, and oral biofilm maintenance and they participated in the elaboration of the paper	were in charge of the saliva collection, laboratory processing, and oral biofilm maintenance and they participated in the elaboration of the paper	-	-	NO
4529887	26273590	Sergio A. Gehrke	2	were in charge of the saliva collection, laboratory processing, and oral biofilm maintenance and they participated in the elaboration of the paper	were in charge of the saliva collection, laboratory processing, and oral biofilm maintenance and they participated in the elaboration of the paper	-	-	NO
4529887	26273590	Tatiane Ferreira Miato	2	were in charge of the saliva collection, laboratory processing, and oral biofilm maintenance and they participated in the elaboration of the paper	were in charge of the saliva collection, laboratory processing, and oral biofilm maintenance and they participated in the elaboration of the paper	-	-	NO
5374662	28361693	LW	2	designed the bioinformatics methods and pipelines, performed implementation and wrote the manuscript	designed the bioinformatics methods and pipelines, performed implementation and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5374662	28361693	WWBG	2	designed the bioinformatics methods and pipelines, performed implementation and wrote the manuscript	designed the bioinformatics methods and pipelines, performed implementation and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4407986	25906149	EW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4407986	25906149	EW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4407986	25906149	EW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4407986	25906149	EW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4407986	25906149	GMW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4407986	25906149	GMW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4407986	25906149	GMW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4407986	25906149	GMW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4407986	25906149	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4407986	25906149	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4407986	25906149	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4407986	25906149	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4407986	25906149	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4407986	25906149	SMJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4407986	25906149	SMJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4407986	25906149	SMJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4407986	25906149	SMJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5591941	28928752	GK-G	PLoS52	did the bioinformatics analysis	did the bioinformatics analysis	-	Formal analysis	YES
5591941	28928752	HH	PLoS52	did the bioinformatics analysis	did the bioinformatics analysis	-	Formal analysis	YES
5591941	28928752	JW	PLoS52	provided the support and expertise on the qtl icimapping software used to develop the next-generation linkage map and qtl analyses for the study	provided the support and expertise on the qtl icimapping software used to develop the next-generation linkage map and qtl analyses for the study	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Software	YES
5591941	28928752	KaS	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5591941	28928752	KeS	PLoS52	provided the statistical expertise and conducted the analyses for the ivft methanogenic potential data	provided the statistical expertise and conducted the analyses for the ivft methanogenic potential data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5591941	28928752	PB	PLoS52	did the bioinformatics analysis	did the bioinformatics analysis	-	Formal analysis	YES
5591941	28928752	PK	PLoS52	performed the experiments|performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5591941	28928752	PK	PLoS52	performed the experiments|performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5591941	28928752	SI	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
3835620	24246064	All the authors	2	participated to the research	participated to the research	-	-	NO
3835620	24246064	BF	2	wrote the first version of the paper that has then been edited by all the authors	wrote the first version of the paper that has then been edited by all the authors	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6230542	30417316	ABM	2	are the guarantors of integrity of the entire study	are the guarantors of integrity of the entire study	-	-	NO
6230542	30417316	All authors	2	contributed to the study concepts/study design, data acquisition, data analysis/interpretation, manuscript drafting, manuscript revision for important intellectual content, literature research, and manuscript editing|approved the final version of the manuscript|agree to ensure that any questions related to the work are appropriately resolved	contributed to the study concepts/study design, data acquisition, data analysis/interpretation, manuscript drafting, manuscript revision for important intellectual content, literature research, and manuscript editing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
6230542	30417316	All authors	2	contributed to the study concepts/study design, data acquisition, data analysis/interpretation, manuscript drafting, manuscript revision for important intellectual content, literature research, and manuscript editing|approved the final version of the manuscript|agree to ensure that any questions related to the work are appropriately resolved	approved the final version of the manuscript	-	-	NO
6230542	30417316	All authors	2	contributed to the study concepts/study design, data acquisition, data analysis/interpretation, manuscript drafting, manuscript revision for important intellectual content, literature research, and manuscript editing|approved the final version of the manuscript|agree to ensure that any questions related to the work are appropriately resolved	agree to ensure that any questions related to the work are appropriately resolved	-	-	NO
6230542	30417316	FL	2	are the guarantors of integrity of the entire study|contributed to the clinical studies|contributed to the experimental studies and statistical analysis	are the guarantors of integrity of the entire study	-	-	NO
6230542	30417316	FL	2	are the guarantors of integrity of the entire study|contributed to the clinical studies|contributed to the experimental studies and statistical analysis	contributed to the clinical studies	-	-	NO
6230542	30417316	FL	2	are the guarantors of integrity of the entire study|contributed to the clinical studies|contributed to the experimental studies and statistical analysis	contributed to the experimental studies and statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6230542	30417316	HJ	2	are the guarantors of integrity of the entire study|contributed to the clinical studies|contributed to the experimental studies and statistical analysis	are the guarantors of integrity of the entire study	-	-	NO
6230542	30417316	HJ	2	are the guarantors of integrity of the entire study|contributed to the clinical studies|contributed to the experimental studies and statistical analysis	contributed to the clinical studies	-	-	NO
6230542	30417316	HJ	2	are the guarantors of integrity of the entire study|contributed to the clinical studies|contributed to the experimental studies and statistical analysis	contributed to the experimental studies and statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6230542	30417316	TB	2	are the guarantors of integrity of the entire study|contributed to the clinical studies	are the guarantors of integrity of the entire study	-	-	NO
6230542	30417316	TB	2	are the guarantors of integrity of the entire study|contributed to the clinical studies	contributed to the clinical studies	-	-	NO
4407987	25905490	AMC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4407987	25905490	DKY	PLoS5	Administrative support	Administrative support	-	Project administration	YES
4407987	25905490	FKC	PLoS5	Administrative support	Administrative support	-	Project administration	YES
4407987	25905490	GLW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4407987	25905490	HLC	PLoS5	Administrative support	Administrative support	-	Project administration	YES
4407987	25905490	JW	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4407987	25905490	JW	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4407987	25905490	LSL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4407987	25905490	MMS	PLoS5	Administrative support	Administrative support	-	Project administration	YES
4407987	25905490	RC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4407987	25905490	RC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4407987	25905490	RC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4407987	25905490	RC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4407987	25905490	VWW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4407987	25905490	VWW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4407987	25905490	VWW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4407987	25905490	VWW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4407987	25905490	WCC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
6246752	30460577	AK	2	analysed the acquired data and drafted the manuscript	analysed the acquired data and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6246752	30460577	All authors	2	provided critical review and approved the final manuscript	provided critical review and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6246752	30460577	DV	2	participated in the data collection	participated in the data collection	Performed the experiments	Investigation	YES
6246752	30460577	MH	2	participated in the data collection and analysis	participated in the data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6246752	30460577	RB	2	conceived of the study, participated in data collection, study design and coordination and helped to draft the manuscript	conceived of the study, participated in data collection, study design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Project administration|Writing - Original Draft	YES
6246752	30460577	TS	2	helped to draft the manuscript	helped to draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5591944	28928760	BL	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5591944	28928760	BL	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5591944	28928760	DX	PLoS52	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5591944	28928760	HG	PLoS52	performed the experiments|analyzed the data|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5591944	28928760	HG	PLoS52	performed the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5591944	28928760	HG	PLoS52	performed the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5591944	28928760	HH	PLoS52	performed the experiments|analyzed the data|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5591944	28928760	HH	PLoS52	performed the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5591944	28928760	HH	PLoS52	performed the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5591944	28928760	JT	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5591944	28928760	JT	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5591944	28928760	LX	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5591944	28928760	LX	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5591944	28928760	SS	PLoS52	designed the study|performed the experiments|analyzed the data|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5591944	28928760	SS	PLoS52	designed the study|performed the experiments|analyzed the data|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5591944	28928760	SS	PLoS52	designed the study|performed the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5591944	28928760	SS	PLoS52	designed the study|performed the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5591944	28928760	TQ	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5591944	28928760	TQ	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5031873	27672451	Both authors	PLoS52	conceptualized the study and collected and supervised data collection, interpreted the findings, and read and approved the final manuscript	conceptualized the study and collected and supervised data collection, interpreted the findings, and read and approved the final manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Supervision|Writing - Review & Editing	YES
5031873	27672451	Mathildah Mokgatle	PLoS52	analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
5031873	27672451	Sphiwe Madiba	PLoS52	drafted the manuscript and finalized the writing of the manuscript	drafted the manuscript and finalized the writing of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5374680	28359301	AU	2	conceived the study, performed data analysis and wrote the manuscript	conceived the study, performed data analysis and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
5374680	28359301	AW	2	provided scripts for random pruning and edited the manuscript	provided scripts for random pruning and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5374680	28359301	FB	2	provided scripts for random pruning and edited the manuscript	provided scripts for random pruning and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5374680	28359301	IGM	2	conceived the study, performed data analysis and wrote the manuscript|helped the conceptual design of the study, the preparation of the manuscript, and the interpretation of the results	conceived the study, performed data analysis and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
5374680	28359301	IGM	2	conceived the study, performed data analysis and wrote the manuscript|helped the conceptual design of the study, the preparation of the manuscript, and the interpretation of the results	helped the conceptual design of the study, the preparation of the manuscript, and the interpretation of the results	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
5374680	28359301	OAA	2	edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5374680	28359301	VZ	2	conceived the study, performed data analysis and wrote the manuscript	conceived the study, performed data analysis and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
3846629	24006875	All authors	2	contributed equally to the drafting and re-drafting of the paper, as well as development of ideas and concepts on which the paper is based	contributed equally to the drafting and re-drafting of the paper, as well as development of ideas and concepts on which the paper is based	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
3846629	24006875	RLA	2	led the project	led the project	-	-	NO
3846629	24006875	The authors	2	contributions are related to their respective areas of current research and expertise	contributions are related to their respective areas of current research and expertise	-	-	NO
5515054	28605174	FEM	2	contributed to study design and review of the study instruments, and writing the manuscript	contributed to study design and review of the study instruments, and writing the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5515054	28605174	IFS	2	contributed to study design and review of the study instruments, and writing the manuscript	contributed to study design and review of the study instruments, and writing the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5515054	28605174	LMA	2	contributed to the study conception and review of the study instruments, participated in data collection, analysis and writing of the manuscript	contributed to the study conception and review of the study instruments, participated in data collection, analysis and writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5515054	28605174	MD	2	contributed to the study conception and review of the study instruments, analysis and writing of the manuscript	contributed to the study conception and review of the study instruments, analysis and writing of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
5515054	28605174	SPSK	2	conceived the study, designed research instruments, managed the data collection, led the data analysis and drafting of the manuscript	conceived the study, designed research instruments, managed the data collection, led the data analysis and drafting of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Data curation|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5591945	28928762	All authors	2	contributed to data analysis and the writing of the manuscript	contributed to data analysis and the writing of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5591945	28928762	GG	2	conceived the project|planned, designed and supervised the research	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5591945	28928762	GG	2	conceived the project|planned, designed and supervised the research	planned, designed and supervised the research	Conceived and designed the experiments	Conceptualization|Methodology|Supervision	YES
5591945	28928762	GN	2	planned, designed and supervised the research	planned, designed and supervised the research	Conceived and designed the experiments	Conceptualization|Methodology|Supervision	YES
5591945	28928762	LM	2	performed the experiments and contributed equally to this work	performed the experiments and contributed equally to this work	Performed the experiments	Investigation	YES
5591945	28928762	MH	2	planned, designed and supervised the research	planned, designed and supervised the research	Conceived and designed the experiments	Conceptualization|Methodology|Supervision	YES
5591945	28928762	MK	2	performed the experiments and contributed equally to this work	performed the experiments and contributed equally to this work	Performed the experiments	Investigation	YES
5591945	28928762	SK	2	performed the experiments and contributed equally to this work	performed the experiments and contributed equally to this work	Performed the experiments	Investigation	YES
3847359	24010636	FAC	2	assisted with survey development and helped to draft the manuscript	assisted with survey development and helped to draft the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3847359	24010636	JCT	2	conceived of the study, assisted with survey development, and helped to draft the manuscript	conceived of the study, assisted with survey development, and helped to draft the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
3847359	24010636	KMJ	2	assisted with survey development, performed the statistical analyses, and helped to draft the manuscript	assisted with survey development, performed the statistical analyses, and helped to draft the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3847359	24010636	RMA	2	conceived of the study, assisted with survey development, and drafted the manuscript	conceived of the study, assisted with survey development, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
6265358	30498973	BSM	2	helped in acquiring data and revising the manuscript	helped in acquiring data and revising the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
6265358	30498973	DO	2	helped in acquiring data and revising the manuscript	helped in acquiring data and revising the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
6265358	30498973	JKM	2	were the primary writers of the manuscript, performed data collection, analysis, and interpretation	were the primary writers of the manuscript, performed data collection, analysis, and interpretation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6265358	30498973	KCC	2	helped in acquiring data and revising the manuscript	helped in acquiring data and revising the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
6265358	30498973	KCY	2	helped in critically interpreting the data and in revising the manuscript	helped in critically interpreting the data and in revising the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
6265358	30498973	MJS	2	performed statistical analysis and aided in drafting the manuscript	performed statistical analysis and aided in drafting the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6265358	30498973	PLR	2	helped in critically interpreting the data and in revising the manuscript	helped in critically interpreting the data and in revising the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
6265358	30498973	RKK	2	performed registrations and morphological segmentations and reviewed the manuscript	performed registrations and morphological segmentations and reviewed the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
6265358	30498973	RNS	2	helped in acquiring data and revising the manuscript	helped in acquiring data and revising the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
6265358	30498973	TD	2	performed statistical analysis and aided in drafting the manuscript	performed statistical analysis and aided in drafting the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6265358	30498973	YKD	2	were the primary writers of the manuscript, performed data collection, analysis, and interpretation	were the primary writers of the manuscript, performed data collection, analysis, and interpretation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5374683	28361709	All authors	2	revised and improved the paper, and have read and approved the final manuscript	revised and improved the paper, and have read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5374683	28361709	JE	2	provided expert suggestions on the idea and the writing of this paper	provided expert suggestions on the idea and the writing of this paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5374683	28361709	JL	2	proposed the idea of heterogeneity learning and applying it in epitope prediction	proposed the idea of heterogeneity learning and applying it in epitope prediction	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
5374683	28361709	JR	2	planned and participated in the entire study from data collection, algorithm design to paper writing	planned and participated in the entire study from data collection, algorithm design to paper writing	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Investigation|Methodology|Software	YES
5374683	28361709	JS	2	provided expert suggestions on the idea and the writing of this paper	provided expert suggestions on the idea and the writing of this paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4408004	25906397	AC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408004	25906397	AC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408004	25906397	AC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408004	25906397	ADB	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408004	25906397	ADB	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408004	25906397	ADB	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408004	25906397	AG	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408004	25906397	AG	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408004	25906397	AG	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408004	25906397	DC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408004	25906397	DC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408004	25906397	DC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408004	25906397	DC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408004	25906397	DC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408004	25906397	DT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408004	25906397	DT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408004	25906397	DT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408004	25906397	EMG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408004	25906397	EMG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408004	25906397	EMG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408004	25906397	GE	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408004	25906397	GE	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408004	25906397	GE	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408004	25906397	GP	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408004	25906397	GP	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408004	25906397	GP	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408004	25906397	LP	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408004	25906397	LP	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408004	25906397	RF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408004	25906397	RF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408004	25906397	RF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408004	25906397	SP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408004	25906397	SP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408004	25906397	SP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3853249	24131854	BLB	1	Concept and design|Collection and assembly of the data|Data analysis and interpretation|Drafting of the article|Critical revision of the article|Obtaining of funding	Concept and design	Conceived and designed the experiments	Conceptualization	YES
3853249	24131854	BLB	1	Concept and design|Collection and assembly of the data|Data analysis and interpretation|Drafting of the article|Critical revision of the article|Obtaining of funding	Collection and assembly of the data	Performed the experiments	Investigation	YES
3853249	24131854	BLB	1	Concept and design|Collection and assembly of the data|Data analysis and interpretation|Drafting of the article|Critical revision of the article|Obtaining of funding	Data analysis and interpretation	Analyzed the data	Formal analysis	YES
3853249	24131854	BLB	1	Concept and design|Collection and assembly of the data|Data analysis and interpretation|Drafting of the article|Critical revision of the article|Obtaining of funding	Drafting of the article	Wrote the paper	Writing - Original Draft	YES
3853249	24131854	BLB	1	Concept and design|Collection and assembly of the data|Data analysis and interpretation|Drafting of the article|Critical revision of the article|Obtaining of funding	Critical revision of the article	Wrote the paper	Writing - Review & Editing	YES
3853249	24131854	BLB	1	Concept and design|Collection and assembly of the data|Data analysis and interpretation|Drafting of the article|Critical revision of the article|Obtaining of funding	Obtaining of funding	-	Funding acquisition	YES
3853249	24131854	ED	1	Data analysis and interpretation|Critical revision of the article	Data analysis and interpretation	Analyzed the data	Formal analysis	YES
3853249	24131854	ED	1	Data analysis and interpretation|Critical revision of the article	Critical revision of the article	Wrote the paper	Writing - Review & Editing	YES
3853249	24131854	JI	1	Concept and design|Collection and assembly of the data|Data analysis and interpretation|Drafting of the article|Critical revision of the article|Obtaining of funding	Concept and design	Conceived and designed the experiments	Conceptualization	YES
3853249	24131854	JI	1	Concept and design|Collection and assembly of the data|Data analysis and interpretation|Drafting of the article|Critical revision of the article|Obtaining of funding	Collection and assembly of the data	Performed the experiments	Investigation	YES
3853249	24131854	JI	1	Concept and design|Collection and assembly of the data|Data analysis and interpretation|Drafting of the article|Critical revision of the article|Obtaining of funding	Data analysis and interpretation	Analyzed the data	Formal analysis	YES
3853249	24131854	JI	1	Concept and design|Collection and assembly of the data|Data analysis and interpretation|Drafting of the article|Critical revision of the article|Obtaining of funding	Drafting of the article	Wrote the paper	Writing - Original Draft	YES
3853249	24131854	JI	1	Concept and design|Collection and assembly of the data|Data analysis and interpretation|Drafting of the article|Critical revision of the article|Obtaining of funding	Critical revision of the article	Wrote the paper	Writing - Review & Editing	YES
3853249	24131854	JI	1	Concept and design|Collection and assembly of the data|Data analysis and interpretation|Drafting of the article|Critical revision of the article|Obtaining of funding	Obtaining of funding	-	Funding acquisition	YES
3853249	24131854	LB	1	Collection and assembly of the data|Data analysis and interpretation|Critical revision of the article	Collection and assembly of the data	Performed the experiments	Investigation	YES
3853249	24131854	LB	1	Collection and assembly of the data|Data analysis and interpretation|Critical revision of the article	Data analysis and interpretation	Analyzed the data	Formal analysis	YES
3853249	24131854	LB	1	Collection and assembly of the data|Data analysis and interpretation|Critical revision of the article	Critical revision of the article	Wrote the paper	Writing - Review & Editing	YES
3853249	24131854	RV	1	Data analysis and interpretation|Critical revision of the article	Data analysis and interpretation	Analyzed the data	Formal analysis	YES
3853249	24131854	RV	1	Data analysis and interpretation|Critical revision of the article	Critical revision of the article	Wrote the paper	Writing - Review & Editing	YES
3853249	24131854	SS	1	Concept and design|Collection and assembly of the data|Data analysis and interpretation|Drafting of the article|Critical revision of the article	Concept and design	Conceived and designed the experiments	Conceptualization	YES
3853249	24131854	SS	1	Concept and design|Collection and assembly of the data|Data analysis and interpretation|Drafting of the article|Critical revision of the article	Collection and assembly of the data	Performed the experiments	Investigation	YES
3853249	24131854	SS	1	Concept and design|Collection and assembly of the data|Data analysis and interpretation|Drafting of the article|Critical revision of the article	Data analysis and interpretation	Analyzed the data	Formal analysis	YES
3853249	24131854	SS	1	Concept and design|Collection and assembly of the data|Data analysis and interpretation|Drafting of the article|Critical revision of the article	Drafting of the article	Wrote the paper	Writing - Original Draft	YES
3853249	24131854	SS	1	Concept and design|Collection and assembly of the data|Data analysis and interpretation|Drafting of the article|Critical revision of the article	Critical revision of the article	Wrote the paper	Writing - Review & Editing	YES
3853249	24131854	all authors	1	Final approval of the article	Final approval of the article	-	-	NO
5078638	27807481	Both authors	2	were responsible for the study concept, design, and implementation and interpretation of data	were responsible for the study concept, design, and implementation and interpretation of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation|Methodology	YES
5078638	27807481	Mathildah Mokgatle	2	supervised all the aspects of data collection and capturing|reviewed the paper, and both authors reviewed and accepted the final version of the paper	supervised all the aspects of data collection and capturing	Performed the experiments	Investigation|Supervision	YES
5078638	27807481	Mathildah Mokgatle	2	supervised all the aspects of data collection and capturing|reviewed the paper, and both authors reviewed and accepted the final version of the paper	reviewed the paper, and both authors reviewed and accepted the final version of the paper	Wrote the paper	Writing - Review & Editing	YES
5078638	27807481	Sphiwe Madiba	2	drafted the paper and performed the analysis	drafted the paper and performed the analysis	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5592229	28932231	AF	4	Plant materials were developed by|Cytogenetic checking was carried out by	Plant materials were developed by	Performed the experiments	Investigation	YES
5592229	28932231	AF	4	Plant materials were developed by|Cytogenetic checking was carried out by	Cytogenetic checking was carried out by	Performed the experiments	Investigation	YES
5592229	28932231	AL	4	Experimentation and data evaluation were carried out by|Paper was written by	Experimentation and data evaluation were carried out by	Performed the experiments	Investigation	YES
5592229	28932231	AL	4	Experimentation and data evaluation were carried out by|Paper was written by	Paper was written by	Wrote the paper	Writing - Original Draft	YES
5592229	28932231	ED	4	Plant materials were developed by|Paper was written by	Plant materials were developed by	Performed the experiments	Investigation	YES
5592229	28932231	ED	4	Plant materials were developed by|Paper was written by	Paper was written by	Wrote the paper	Writing - Original Draft	YES
5592229	28932231	IM	4	Plant materials were developed by|Background for research was established by|Blast searches were carried out by|Paper was written by	Plant materials were developed by	Performed the experiments	Investigation	YES
5592229	28932231	IM	4	Plant materials were developed by|Background for research was established by|Blast searches were carried out by|Paper was written by	Background for research was established by	-	-	NO
5592229	28932231	IM	4	Plant materials were developed by|Background for research was established by|Blast searches were carried out by|Paper was written by	Blast searches were carried out by	Performed the experiments	Investigation	YES
5592229	28932231	IM	4	Plant materials were developed by|Background for research was established by|Blast searches were carried out by|Paper was written by	Paper was written by	Wrote the paper	Writing - Original Draft	YES
5592229	28932231	JD	4	Sequence data of the u genome of Aegilops umbellulata were made available by	Sequence data of the u genome of Aegilops umbellulata were made available by	Performed the experiments	Investigation	YES
5592229	28932231	LL	4	Background for research was established by	Background for research was established by	-	-	NO
5592229	28932231	MM-L	4	Plant materials were developed by	Plant materials were developed by	Performed the experiments	Investigation	YES
5592229	28932231	MR	4	Experimentation and data evaluation were carried out by|Paper was written by	Experimentation and data evaluation were carried out by	Performed the experiments	Investigation	YES
5592229	28932231	MR	4	Experimentation and data evaluation were carried out by|Paper was written by	Paper was written by	Wrote the paper	Writing - Original Draft	YES
5592229	28932231	PS	4	Experimentation and data evaluation were carried out by|Background for research was established by|Paper was written by	Experimentation and data evaluation were carried out by	Performed the experiments	Investigation	YES
5592229	28932231	PS	4	Experimentation and data evaluation were carried out by|Background for research was established by|Paper was written by	Background for research was established by	-	-	NO
5592229	28932231	PS	4	Experimentation and data evaluation were carried out by|Background for research was established by|Paper was written by	Paper was written by	Wrote the paper	Writing - Original Draft	YES
5592229	28932231	ZB	4	Background for research was established by	Background for research was established by	-	-	NO
6269439	30506174	FL	2	designed this study	designed this study	Conceived and designed the experiments	Methodology	YES
6269439	30506174	HW	2	carried out the nema measurements|performed data analysis	carried out the nema measurements	Performed the experiments	Investigation	YES
6269439	30506174	HW	2	carried out the nema measurements|performed data analysis	performed data analysis	Analyzed the data	Formal analysis	YES
6269439	30506174	HX	2	carried out the nema measurements|recruited the patients and performed the clinical study	carried out the nema measurements	Performed the experiments	Investigation	YES
6269439	30506174	HX	2	carried out the nema measurements|recruited the patients and performed the clinical study	recruited the patients and performed the clinical study	Performed the experiments	Investigation	YES
6269439	30506174	HZ	2	designed this study|prepared the manuscript	designed this study	Conceived and designed the experiments	Methodology	YES
6269439	30506174	HZ	2	designed this study|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
6269439	30506174	JB	2	recruited the patients and performed the clinical study	recruited the patients and performed the clinical study	Performed the experiments	Investigation	YES
6269439	30506174	LH	2	designed this study|performed data analysis|prepared the manuscript	designed this study	Conceived and designed the experiments	Methodology	YES
6269439	30506174	LH	2	designed this study|performed data analysis|prepared the manuscript	performed data analysis	Analyzed the data	Formal analysis	YES
6269439	30506174	LH	2	designed this study|performed data analysis|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
6269439	30506174	NL	2	carried out the nema measurements|performed data analysis	carried out the nema measurements	Performed the experiments	Investigation	YES
6269439	30506174	NL	2	carried out the nema measurements|performed data analysis	performed data analysis	Analyzed the data	Formal analysis	YES
6269439	30506174	TW	2	carried out the nema measurements|recruited the patients and performed the clinical study	carried out the nema measurements	Performed the experiments	Investigation	YES
6269439	30506174	TW	2	carried out the nema measurements|recruited the patients and performed the clinical study	recruited the patients and performed the clinical study	Performed the experiments	Investigation	YES
6269439	30506174	WZ	2	recruited the patients and performed the clinical study	recruited the patients and performed the clinical study	Performed the experiments	Investigation	YES
5374686	28361692	DL	2	conceived the study, performed the experiments, and wrote the paper	conceived the study, performed the experiments, and wrote the paper	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
5374686	28361692	GH	2	reviewed and revised the manuscript	reviewed and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5374686	28361692	SH	2	conceived the study, performed the experiments, and wrote the paper	conceived the study, performed the experiments, and wrote the paper	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
5374686	28361692	ZP	2	reviewed and revised the manuscript	reviewed and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5374686	28361692	ZZ	2	reviewed and revised the manuscript	reviewed and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4408006	25906073	HW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408006	25906073	HW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408006	25906073	HW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408006	25906073	KZ	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4408006	25906073	MT	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408006	25906073	MT	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408006	25906073	MT	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408006	25906073	MT	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408006	25906073	XC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408006	25906073	XT	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408006	25906073	XT	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408006	25906073	XT	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408006	25906073	XZ	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4408006	25906073	XZ	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
3854005	23962355	MAM	2	participated in the design of the study, performed the analysis especially for the parts of the article that concern the situation in germany and contributed in drafting the manuscript	participated in the design of the study, performed the analysis especially for the parts of the article that concern the situation in germany and contributed in drafting the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
3854005	23962355	SB	2	participated in the design of the study, performed the analysis especially for the parts of the article that concern the situation in israel and drafted the manuscript	participated in the design of the study, performed the analysis especially for the parts of the article that concern the situation in israel and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5515058	28530034	CeSHHAR	2	contributed to writing the manuscript	contributed to writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5515058	28530034	DH	2	were involved in the legal case, reviewed and commented on several drafts	were involved in the legal case, reviewed and commented on several drafts	Wrote the paper	Writing - Original Draft	YES
5515058	28530034	EF	2	conducted rds survey analysis	conducted rds survey analysis	Performed the experiments	Investigation	YES
5515058	28530034	FM	2	reviewed and commented on drafts	reviewed and commented on drafts	Wrote the paper	Writing - Original Draft	YES
5515058	28530034	FSW	2	documented peer educators experiences and provided feedback for early drafts	documented peer educators experiences and provided feedback for early drafts	Wrote the paper	Writing - Original Draft	YES
5515058	28530034	JB	2	developed the idea for the article and wrote the first draft	developed the idea for the article and wrote the first draft	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5515058	28530034	OM	2	reviewed and commented on drafts	reviewed and commented on drafts	Wrote the paper	Writing - Original Draft	YES
5515058	28530034	RY	2	reviewed and commented on drafts	reviewed and commented on drafts	Wrote the paper	Writing - Original Draft	YES
5515058	28530034	TM	2	were involved in the legal case, reviewed and commented on several drafts	were involved in the legal case, reviewed and commented on several drafts	Wrote the paper	Writing - Original Draft	YES
5592238	28932233	All authors	2	made substantial contributions to the revision of the manuscript	made substantial contributions to the revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5592238	28932233	DG	2	developed the idea	developed the idea	Conceived and designed the experiments	Conceptualization	YES
5592238	28932233	LL	2	developed the idea|prepared the first draft of the manuscript	developed the idea	Conceived and designed the experiments	Conceptualization	YES
5592238	28932233	LL	2	developed the idea|prepared the first draft of the manuscript	prepared the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
4408007	25905625	AAMJB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408007	25905625	AAMJB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408007	25905625	AAMJB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408007	25905625	AAMJB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408007	25905625	AAMJB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408007	25905625	CS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4408007	25905625	CS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408007	25905625	GH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408007	25905625	GH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408007	25905625	GH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408007	25905625	GH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408007	25905625	GPJJ	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408007	25905625	GPJJ	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408007	25905625	MH	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408007	25905625	MH	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3892081	24387102	Both authors	2	contributed to the development and writing of this manuscript and approve the final content	contributed to the development and writing of this manuscript and approve the final content	Wrote the paper	Writing - Original Draft	YES
5374702	28361712	BXL	1	Program implementation and experiments|Manuscript preparation	Program implementation and experiments	Performed the experiments	Investigation	YES
5374702	28361712	BXL	1	Program implementation and experiments|Manuscript preparation	Manuscript preparation	Wrote the paper	Writing - Original Draft	YES
5374702	28361712	HWL	1	Manuscript preparation	Manuscript preparation	Wrote the paper	Writing - Original Draft	YES
5374702	28361712	LXZ	1	Project design|Manuscript preparation	Project design	Conceived and designed the experiments	Methodology	YES
5374702	28361712	LXZ	1	Project design|Manuscript preparation	Manuscript preparation	Wrote the paper	Writing - Original Draft	YES
6277405	30511121	HdJ	2	contributed to the design of the study and supervised the project	contributed to the design of the study and supervised the project	Conceived and designed the experiments	Methodology|Supervision	YES
6277405	30511121	MD	2	performed the simulations and drafted the manuscript	performed the simulations and drafted the manuscript	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6277405	30511121	ML	2	contributed to the design of the study	contributed to the design of the study	Conceived and designed the experiments	Methodology	YES
6277405	30511121	MV	2	contributed to the design of the study	contributed to the design of the study	Conceived and designed the experiments	Methodology	YES
6277405	30511121	SvdV	2	provided assistance in the data analysis	provided assistance in the data analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5515059	28453242	AW	2	collaborated in the design and oversight of the overall study|contributed to the design and analysis of qualitative research|wrote the initial drafts of this manuscript	collaborated in the design and oversight of the overall study	Conceived and designed the experiments	Methodology|Supervision	YES
5515059	28453242	AW	2	collaborated in the design and oversight of the overall study|contributed to the design and analysis of qualitative research|wrote the initial drafts of this manuscript	contributed to the design and analysis of qualitative research	Conceived and designed the experiments	Methodology	YES
5515059	28453242	AW	2	collaborated in the design and oversight of the overall study|contributed to the design and analysis of qualitative research|wrote the initial drafts of this manuscript	wrote the initial drafts of this manuscript	Wrote the paper	Writing - Original Draft	YES
5515059	28453242	All authors	2	had full access to the data, reviewed and edited the manuscript, and all take responsibility for its integrity as well as the accuracy of the analysis	had full access to the data, reviewed and edited the manuscript, and all take responsibility for its integrity as well as the accuracy of the analysis	Analyzed the data|Wrote the paper	Data curation|Formal analysis|Writing - Review & Editing	YES
5515059	28453242	CB	2	collaborated in the design and oversight of the overall study	collaborated in the design and oversight of the overall study	Conceived and designed the experiments	Methodology|Supervision	YES
5515059	28453242	EC	2	collaborated in the design and oversight of the overall study|contributed to the design and analysis of qualitative research	collaborated in the design and oversight of the overall study	Conceived and designed the experiments	Methodology|Supervision	YES
5515059	28453242	EC	2	collaborated in the design and oversight of the overall study|contributed to the design and analysis of qualitative research	contributed to the design and analysis of qualitative research	Conceived and designed the experiments	Methodology	YES
5515059	28453242	KHT	2	oversaw qualitative data collection	oversaw qualitative data collection	Performed the experiments	Investigation|Supervision	YES
5515059	28453242	SB	2	collaborated in the design and oversight of the overall study	collaborated in the design and oversight of the overall study	Conceived and designed the experiments	Methodology|Supervision	YES
5515059	28453242	SN	2	collaborated in the design and oversight of the overall study	collaborated in the design and oversight of the overall study	Conceived and designed the experiments	Methodology|Supervision	YES
5515059	28453242	VV	2	contributed to the design and analysis of qualitative research	contributed to the design and analysis of qualitative research	Conceived and designed the experiments	Methodology	YES
5592239	28932232	HS	2	contributed to the analyses	contributed to the analyses	Analyzed the data	Formal analysis	YES
5592239	28932232	JH	2	conceived the study and wrote the manuscript	conceived the study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5592239	28932232	QW	2	performed the analyses and wrote the manuscript	performed the analyses and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4529894	26273622	All authors	2	read and approved the final paper	read and approved the final paper	-	-	NO
4529894	26273622	Dongzi Yang	2	participated in the design, recruitment, and evaluation of subjects and helped in data analysis and revising the paper critically for important intellectual content	participated in the design, recruitment, and evaluation of subjects and helped in data analysis and revising the paper critically for important intellectual content	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
4529894	26273622	Kaiwen Li	2	made substantial contributions to the conception, design, analysis, and interpretation of the data and wrote the paper|contributed equally to this work as co-first authors	made substantial contributions to the conception, design, analysis, and interpretation of the data and wrote the paper	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Resources|Writing - Original Draft	YES
4529894	26273622	Kaiwen Li	2	made substantial contributions to the conception, design, analysis, and interpretation of the data and wrote the paper|contributed equally to this work as co-first authors	contributed equally to this work as co-first authors	-	-	NO
4529894	26273622	Renmin Ni	2	participated in the laboratory aspects of the study and took part in data analysis, interpretation, revision, and approval of the paper	participated in the laboratory aspects of the study and took part in data analysis, interpretation, revision, and approval of the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
4529894	26273622	Tao Du	2	contributed equally to this work as co-first authors	contributed equally to this work as co-first authors	-	-	NO
4529894	26273622	Xiaomiao Zhao	2	participated in the laboratory aspects of the study and took part in data analysis, interpretation, revision, and approval of the paper	participated in the laboratory aspects of the study and took part in data analysis, interpretation, revision, and approval of the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
4529894	26273622	Yu Duan	2	contributed equally to this work as co-first authors	contributed equally to this work as co-first authors	-	-	NO
4529894	26273622	Yu Li	2	participated in the laboratory aspects of the study and took part in data analysis, interpretation, revision, and approval of the paper	participated in the laboratory aspects of the study and took part in data analysis, interpretation, revision, and approval of the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
3901751	24423249	All authors	2	planned and elucidated the layout	planned and elucidated the layout	Conceived and designed the experiments	Conceptualization	YES
5374703	28361695	DH	2	proposed the project and suggested the mapping procedures	proposed the project and suggested the mapping procedures	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5374703	28361695	MB	2	designed and implemented the code and carried out the comparisons	designed and implemented the code and carried out the comparisons	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5592274	28932230	SL	2	performed the phenotyping measurement	performed the phenotyping measurement	Performed the experiments	Investigation	YES
5592274	28932230	XG	2	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5592274	28932230	YS	2	performed the phenotyping measurement|performed the data analysis	performed the phenotyping measurement	Performed the experiments	Investigation	YES
5592274	28932230	YS	2	performed the phenotyping measurement|performed the data analysis	performed the data analysis	Analyzed the data	Formal analysis	YES
5592274	28932230	YY	2	performed the phenotyping measurement|performed the data analysis|wrote the manuscript and all authors reviewed and edited the manuscript	performed the phenotyping measurement	Performed the experiments	Investigation	YES
5592274	28932230	YY	2	performed the phenotyping measurement|performed the data analysis|wrote the manuscript and all authors reviewed and edited the manuscript	performed the data analysis	Analyzed the data	Formal analysis	YES
5592274	28932230	YY	2	performed the phenotyping measurement|performed the data analysis|wrote the manuscript and all authors reviewed and edited the manuscript	wrote the manuscript and all authors reviewed and edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5592274	28932230	ZL	2	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408008	25905708	DKA	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408008	25905708	HP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408008	25905708	HP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4408008	25905708	HP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4408008	25905708	HP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408008	25905708	JY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408008	25905708	JY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408008	25905708	JY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408008	25905708	JY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408008	25905708	TL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408008	25905708	TL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4408008	25905708	TL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4408008	25905708	YL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408008	25905708	YL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408008	25905708	YL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408008	25905708	YL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408008	25905708	ZL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408008	25905708	ZL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408008	25905708	ZL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3901785	24345280	IQ	2	have contributed equally to the study, from conceptualising the problem, review of literature and designing research and formulating the tools|along with the research team conducted the field work	have contributed equally to the study, from conceptualising the problem, review of literature and designing research and formulating the tools	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Methodology|Resources	YES
3901785	24345280	IQ	2	have contributed equally to the study, from conceptualising the problem, review of literature and designing research and formulating the tools|along with the research team conducted the field work	along with the research team conducted the field work	Performed the experiments	Investigation	YES
3901785	24345280	SR	2	have contributed equally to the study, from conceptualising the problem, review of literature and designing research and formulating the tools|along with the research team conducted the field work	have contributed equally to the study, from conceptualising the problem, review of literature and designing research and formulating the tools	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Methodology|Resources	YES
3901785	24345280	SR	2	have contributed equally to the study, from conceptualising the problem, review of literature and designing research and formulating the tools|along with the research team conducted the field work	along with the research team conducted the field work	Performed the experiments	Investigation	YES
6281548	30519974	CT	2	conceived the original idea, supervised the study and helped with restructuring of the manuscript and the revision process	conceived the original idea, supervised the study and helped with restructuring of the manuscript and the revision process	Conceived and designed the experiments|Wrote the paper	Conceptualization|Supervision|Writing - Review & Editing	YES
6281548	30519974	E Toolbox	2	also helped towards reading and reconstructing the ge data using stir software	also helped towards reading and reconstructing the ge data using stir software	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
6281548	30519974	JS	2	developed the background correction method and also contributed some ideas towards the study	developed the background correction method and also contributed some ideas towards the study	Conceived and designed the experiments|Performed the experiments	Conceptualization|Methodology	YES
6281548	30519974	MIA	2	designed the study, performed data simulation and reconstructions, analysed the results and wrote the manuscript	designed the study, performed data simulation and reconstructions, analysed the results and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
6281548	30519974	WH	2	helped with the phantom and patient data acquisition	helped with the phantom and patient data acquisition	Performed the experiments	Investigation	YES
4529895	26273623	Jianlin Huang	2	carried out collection of clinical data	carried out collection of clinical data	Performed the experiments	Investigation	YES
4529895	26273623	Jieruo Gu	2	carried out experimental design	carried out experimental design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4529895	26273623	Ou Jin	2	carried out collection of clinical data	carried out collection of clinical data	Performed the experiments	Investigation	YES
4529895	26273623	Peizhuo Zhang	2	carried out experiment of microarray	carried out experiment of microarray	Performed the experiments	Investigation	YES
4529895	26273623	Qing Lv	2	carried out experimental analysis and data statistics|contributed equally to this work	carried out experimental analysis and data statistics	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4529895	26273623	Qing Lv	2	carried out experimental analysis and data statistics|contributed equally to this work	contributed equally to this work	-	-	NO
4529895	26273623	Qiujing Wei	2	carried out collection of samples	carried out collection of samples	Performed the experiments	Investigation	YES
4529895	26273623	Qiuxia Li	2	carried out experimental analysis and data statistics|contributed equally to this work	carried out experimental analysis and data statistics	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4529895	26273623	Qiuxia Li	2	carried out experimental analysis and data statistics|contributed equally to this work	contributed equally to this work	-	-	NO
4529895	26273623	Shuangyan Cao	2	carried out collection of clinical data	carried out collection of clinical data	Performed the experiments	Investigation	YES
4529895	26273623	Tianwang Li	2	carried out collection of clinical data	carried out collection of clinical data	Performed the experiments	Investigation	YES
4529895	26273623	Xinwei Wang	2	carried out rna purification	carried out rna purification	Performed the experiments	Investigation	YES
4529895	26273623	Yingjuan Jiang	2	carried out experiment of microarray	carried out experiment of microarray	Performed the experiments	Investigation	YES
4529895	26273623	Yunfeng Pan	2	carried out collection of clinical data	carried out collection of clinical data	Performed the experiments	Investigation	YES
4529895	26273623	Yuqiong Wu	2	carried out collection of clinical data	carried out collection of clinical data	Performed the experiments	Investigation	YES
4529895	26273623	Zetao Liao	2	carried out collection of clinical data	carried out collection of clinical data	Performed the experiments	Investigation	YES
4529895	26273623	Zhiming Lin	2	carried out collection of clinical data	carried out collection of clinical data	Performed the experiments	Investigation	YES
5165142	28050283	Diamant Mossoro-Kpinde	PLoS52	conceived and designed the experiments|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5165142	28050283	Diamant Mossoro-Kpinde	PLoS52	conceived and designed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5165142	28050283	Gerard Gresenguet	PLoS52	contributed to biological collection and ethical committee	contributed to biological collection and ethical committee	-	-	NO
5165142	28050283	Jean de Dieu Longo	PLoS52	contributed to biological collection and ethical committee	contributed to biological collection and ethical committee	-	-	NO
5165142	28050283	Laurent Andreoletti	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5165142	28050283	Laurent Belec	PLoS52	conceived and designed the experiments|analyzed the data|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5165142	28050283	Laurent Belec	PLoS52	conceived and designed the experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5165142	28050283	Laurent Belec	PLoS52	conceived and designed the experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5165142	28050283	Leman Robin	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5165142	28050283	Mathieu Matta	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5165142	28050283	Mohammad-Ali Jenabian	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5165142	28050283	Sydney Mboumba Bouassa	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5374706	28361685	BM	2	helped with the computations and unearthed the biological significance of the identified features	helped with the computations and unearthed the biological significance of the identified features	Performed the experiments	Formal analysis|Investigation	YES
5374706	28361685	DM	2	helped in obtaining tumor samples	helped in obtaining tumor samples	Performed the experiments	Investigation	YES
5374706	28361685	MAW	2	supervised the project	supervised the project	-	Supervision	YES
5374706	28361685	MEA	2	developed the lone star algorithm and applied it to the endometrial cancer data	developed the lone star algorithm and applied it to the endometrial cancer data	Contributed reagents/materials/analysis tools	Software	YES
5374706	28361685	MV	2	supervised the project	supervised the project	-	Supervision	YES
5374706	28361685	NKS	2	developed the software implementation of the lone star algorithm	developed the software implementation of the lone star algorithm	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5374706	28361685	TB	2	collected the data on the training cohort consisting of 100 tumors	collected the data on the training cohort consisting of 100 tumors	Performed the experiments	Investigation	YES
6283804	30523435	AC	2	contributed to the design of this work|wrote the manuscript	contributed to the design of this work	Conceived and designed the experiments	-	YES
6283804	30523435	AC	2	contributed to the design of this work|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6283804	30523435	AS	2	contributed to the design of this work|were responsible for patient recruitment and treatment planning and for the application of the radioembolization procedure	contributed to the design of this work	Conceived and designed the experiments	-	YES
6283804	30523435	AS	2	contributed to the design of this work|were responsible for patient recruitment and treatment planning and for the application of the radioembolization procedure	were responsible for patient recruitment and treatment planning and for the application of the radioembolization procedure	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6283804	30523435	All authors	2	contributed to the design of this work	contributed to the design of this work	Conceived and designed the experiments	-	YES
6283804	30523435	JJ	2	contributed to the design of this work|performed the imaging studies of the patients, as well as organized and transferred the imaging data	contributed to the design of this work	Conceived and designed the experiments	-	YES
6283804	30523435	JJ	2	contributed to the design of this work|performed the imaging studies of the patients, as well as organized and transferred the imaging data	performed the imaging studies of the patients, as well as organized and transferred the imaging data	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
6283804	30523435	KKK	2	contributed to the design of this work|were responsible for patient recruitment and treatment planning and for the application of the radioembolization procedure	contributed to the design of this work	Conceived and designed the experiments	-	YES
6283804	30523435	KKK	2	contributed to the design of this work|were responsible for patient recruitment and treatment planning and for the application of the radioembolization procedure	were responsible for patient recruitment and treatment planning and for the application of the radioembolization procedure	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6283804	30523435	PLE	2	contributed to the design of this work|analyzed the imaging data and performed dosimetry calculations|wrote the manuscript	contributed to the design of this work	Conceived and designed the experiments	-	YES
6283804	30523435	PLE	2	contributed to the design of this work|analyzed the imaging data and performed dosimetry calculations|wrote the manuscript	analyzed the imaging data and performed dosimetry calculations	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
6283804	30523435	PLE	2	contributed to the design of this work|analyzed the imaging data and performed dosimetry calculations|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3415624	22905070	DET	2	revised and approved the final manuscript	revised and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
3415624	22905070	FA	2	collected the data and drafted the manuscript|revised and approved the final manuscript	collected the data and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3415624	22905070	FA	2	collected the data and drafted the manuscript|revised and approved the final manuscript	revised and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
3415624	22905070	MEF	2	revised and approved the final manuscript	revised and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4408009	25905462	DEP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4408009	25905462	H-R	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408009	25905462	H-R	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408009	25905462	H-R	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408009	25905462	HSK	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408009	25905462	HSK	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408009	25905462	HSK	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408009	25905462	HSL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408009	25905462	HSL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408009	25905462	HSL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408009	25905462	HSL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408009	25905462	KUM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408009	25905462	SHC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408009	25905462	YDW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4408009	25905462	YSC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5374730	28361696	CW	2	give important comments on algorithm design and writing	give important comments on algorithm design and writing	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Software	YES
5374730	28361696	CY	2	give important comments on algorithm design and writing	give important comments on algorithm design and writing	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Software	YES
5374730	28361696	JL	2	give important comments on algorithm design and writing	give important comments on algorithm design and writing	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Software	YES
5374730	28361696	MG	2	conceived the study, wrote the software, and wrote the paper	conceived the study, wrote the software, and wrote the paper	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Software|Writing - Original Draft	YES
5374730	28361696	SP	2	designed the method and algorithm	designed the method and algorithm	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Methodology|Software	YES
5374730	28361696	SY	2	wrote the software and do some experiments	wrote the software and do some experiments	Contributed reagents/materials/analysis tools|Wrote the paper	Software|Writing - Original Draft	YES
5374730	28361696	WYs	2	group do wet experiments to verify the correctness of our work	group do wet experiments to verify the correctness of our work	Performed the experiments	Investigation|Validation	YES
5592330	28932234	C-JJ	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6283809	30523429	All authors	2	contributed to design of the study|discussed the results and implications and commented on the manuscript	contributed to design of the study	Conceived and designed the experiments	Methodology	YES
6283809	30523429	All authors	2	contributed to design of the study|discussed the results and implications and commented on the manuscript	discussed the results and implications and commented on the manuscript	-	-	NO
6283809	30523429	JD	2	performed data collection and analysis	performed data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6283809	30523429	LB	2	performed data collection and analysis	performed data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4408010	25905914	AK	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408010	25905914	DC	PLoS5	Supervised the study	Supervised the study	-	Supervision	YES
4408010	25905914	HJ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4408010	25905914	HS	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4408010	25905914	HYS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4408010	25905914	JHA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408010	25905914	JHA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408010	25905914	JHA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408010	25905914	JHA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408010	25905914	JHH	PLoS5	Conceived and designed the experiments|Wrote the paper|Supervised the study	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408010	25905914	JHH	PLoS5	Conceived and designed the experiments|Wrote the paper|Supervised the study	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408010	25905914	JHH	PLoS5	Conceived and designed the experiments|Wrote the paper|Supervised the study	Supervised the study	-	Supervision	YES
4408010	25905914	JHR	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408010	25905914	JSK	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4408010	25905914	KSK	PLoS5	Supervised the study	Supervised the study	-	Supervision	YES
4408010	25905914	KYY	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408010	25905914	Seungill Kim	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4408010	25905914	Shinje Kim	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
3974225	24679064	CCN	3	Network	Network	-	-	NO
3687480	23844410	Hee Bok Chae	2	acquired the data and wrote the paper	acquired the data and wrote the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3687480	23844410	Sei Jin Youn	2	performed proofreading and critical revision	performed proofreading and critical revision	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
3687480	23844410	Seon Mee Park	2	consulted a direction of the paper	consulted a direction of the paper	-	-	NO
5590093	28936332	D.M.S.	2	developed the proteins and their mutants and performed their biochemical characterization|designed the experiments and analyzed the data|wrote the manuscript	developed the proteins and their mutants and performed their biochemical characterization	Performed the experiments	Investigation	YES
5590093	28936332	D.M.S.	2	developed the proteins and their mutants and performed their biochemical characterization|designed the experiments and analyzed the data|wrote the manuscript	designed the experiments and analyzed the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5590093	28936332	D.M.S.	2	developed the proteins and their mutants and performed their biochemical characterization|designed the experiments and analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5590093	28936332	J.C.L.	2	provided useful ideas and discussed the manuscript	provided useful ideas and discussed the manuscript	Conceived and designed the experiments	Conceptualization	YES
5590093	28936332	M.B.	2	developed the proteins and their mutants and performed their biochemical characterization|designed the experiments and analyzed the data	developed the proteins and their mutants and performed their biochemical characterization	Performed the experiments	Investigation	YES
5590093	28936332	M.B.	2	developed the proteins and their mutants and performed their biochemical characterization|designed the experiments and analyzed the data	designed the experiments and analyzed the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5590093	28936332	S.P.	2	designed the experiments and analyzed the data	designed the experiments and analyzed the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5590093	28936332	V.V.V.	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5590093	28936332	V.Z.P.	2	performed their structural analysis	performed their structural analysis	Performed the experiments	Investigation	YES
6286905	30535780	AC	PLoS52	designed this work|performed dosimetry calculations|analyzed the data|wrote the manuscript	designed this work	Conceived and designed the experiments	-	YES
6286905	30535780	AC	PLoS52	designed this work|performed dosimetry calculations|analyzed the data|wrote the manuscript	performed dosimetry calculations	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6286905	30535780	AC	PLoS52	designed this work|performed dosimetry calculations|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
6286905	30535780	AC	PLoS52	designed this work|performed dosimetry calculations|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6286905	30535780	AM	PLoS52	were responsible for patient recruitment	were responsible for patient recruitment	Performed the experiments	Investigation	YES
6286905	30535780	AS	PLoS52	were responsible for patient recruitment	were responsible for patient recruitment	Performed the experiments	Investigation	YES
6286905	30535780	DJG	PLoS52	were responsible for patient recruitment|revised the manuscript	were responsible for patient recruitment	Performed the experiments	Investigation	YES
6286905	30535780	DJG	PLoS52	were responsible for patient recruitment|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
6286905	30535780	JG	PLoS52	designed this work|were in charge of imaging studies and interpretation of images|wrote the manuscript	designed this work	Conceived and designed the experiments	-	YES
6286905	30535780	JG	PLoS52	designed this work|were in charge of imaging studies and interpretation of images|wrote the manuscript	were in charge of imaging studies and interpretation of images	Analyzed the data	Formal analysis|Visualization	YES
6286905	30535780	JG	PLoS52	designed this work|were in charge of imaging studies and interpretation of images|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6286905	30535780	NF	PLoS52	performed dosimetry calculations|revised the manuscript	performed dosimetry calculations	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6286905	30535780	NF	PLoS52	performed dosimetry calculations|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
6286905	30535780	SG-G	PLoS52	were responsible for patient recruitment|revised the manuscript	were responsible for patient recruitment	Performed the experiments	Investigation	YES
6286905	30535780	SG-G	PLoS52	were responsible for patient recruitment|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
6286905	30535780	YK	PLoS52	were in charge of imaging studies and interpretation of images|revised the manuscript	were in charge of imaging studies and interpretation of images	Analyzed the data	Formal analysis|Visualization	YES
6286905	30535780	YK	PLoS52	were in charge of imaging studies and interpretation of images|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5346378	28331636	All authors	PLoS52	critically reviewed and approved the current version of the manuscript	critically reviewed and approved the current version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5346378	28331636	Grace O. Kolawole	PLoS52	designed the study|collected the qualitative data|analyzed the data|wrote the initial draft of the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5346378	28331636	Grace O. Kolawole	PLoS52	designed the study|collected the qualitative data|analyzed the data|wrote the initial draft of the manuscript	collected the qualitative data	Performed the experiments	Investigation	YES
5346378	28331636	Grace O. Kolawole	PLoS52	designed the study|collected the qualitative data|analyzed the data|wrote the initial draft of the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5346378	28331636	Grace O. Kolawole	PLoS52	designed the study|collected the qualitative data|analyzed the data|wrote the initial draft of the manuscript	wrote the initial draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
5346378	28331636	Hannah N. Gilbert	PLoS52	revised the initial draft	revised the initial draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5346378	28331636	Nancin Y. Dadem	PLoS52	designed the study|collected the qualitative data|analyzed the data	designed the study	Conceived and designed the experiments	Methodology	YES
5346378	28331636	Nancin Y. Dadem	PLoS52	designed the study|collected the qualitative data|analyzed the data	collected the qualitative data	Performed the experiments	Investigation	YES
5346378	28331636	Nancin Y. Dadem	PLoS52	designed the study|collected the qualitative data|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5346378	28331636	Norma C. Ware	PLoS52	designed the study|analyzed the data|revised the initial draft	designed the study	Conceived and designed the experiments	Methodology	YES
5346378	28331636	Norma C. Ware	PLoS52	designed the study|analyzed the data|revised the initial draft	analyzed the data	Analyzed the data	Formal analysis	YES
5346378	28331636	Norma C. Ware	PLoS52	designed the study|analyzed the data|revised the initial draft	revised the initial draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5346378	28331636	Patricia A. Agaba	PLoS52	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5379521	28376783	BYX	2	designed the experiments and contributed to revisions of the manuscript	designed the experiments and contributed to revisions of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5379521	28376783	FL	2	contributed to rna extraction, rt pcr, real time pcr and northern blotting	contributed to rna extraction, rt pcr, real time pcr and northern blotting	Performed the experiments	Investigation	YES
5379521	28376783	JL	2	contributed to bioinformatics analysis and writing of the manuscript	contributed to bioinformatics analysis and writing of the manuscript	Wrote the paper	Formal analysis|Writing - Original Draft	YES
5379521	28376783	YHY	2	helped with the management for cucumber seeding	helped with the management for cucumber seeding	-	-	NO
5379521	28376783	ZQL	2	contributed to rna extraction, rt pcr, real time pcr and northern blotting	contributed to rna extraction, rt pcr, real time pcr and northern blotting	Performed the experiments	Investigation	YES
4408011	25905781	DW	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408011	25905781	DW	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408011	25905781	DW	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408011	25905781	FF	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4408011	25905781	HY	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4408011	25905781	JW	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408011	25905781	JX	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4408011	25905781	JZ	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4408011	25905781	LX	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4408011	25905781	LZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4408011	25905781	MW	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4408011	25905781	MW	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4408011	25905781	NX	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408011	25905781	NX	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4408011	25905781	NX	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408011	25905781	SL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408011	25905781	SL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408011	25905781	SL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408011	25905781	SL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408011	25905781	YG	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4408011	25905781	YL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4408011	25905781	ZK	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4408011	25905781	ZL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4915496	27096255	A.C.	PLoS52	analysed the data and wrote the first draft of the manuscript	analysed the data and wrote the first draft of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4915496	27096255	All authors	PLoS52	commented on and approved the final draft of the manuscript	commented on and approved the final draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
4915496	27096255	P.D.S.	PLoS52	had full access to all of the data in the study and confirms that it is an honest, accurate and transparent account of the study being reported, that no important aspects of the study have been omitted|conceived and designed the study	had full access to all of the data in the study and confirms that it is an honest, accurate and transparent account of the study being reported, that no important aspects of the study have been omitted	Analyzed the data	Data curation	YES
4915496	27096255	P.D.S.	PLoS52	had full access to all of the data in the study and confirms that it is an honest, accurate and transparent account of the study being reported, that no important aspects of the study have been omitted|conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4915496	27096255	R.L.	PLoS52	analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
5594065	28936224	JR	PLoS52	analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5594065	28936224	JR	PLoS52	analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5594065	28936224	LG	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5594065	28936224	M-TH	PLoS52	analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5594065	28936224	M-TH	PLoS52	analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3415629	22896776	All authors	2	participated in interpreting the data and revising the manuscript for important intellectual content|approved the final version of the manuscript	participated in interpreting the data and revising the manuscript for important intellectual content	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
3415629	22896776	All authors	2	participated in interpreting the data and revising the manuscript for important intellectual content|approved the final version of the manuscript	approved the final version of the manuscript	-	-	NO
3415629	22896776	The authors	2	have no relevant affiliations or financial conflict with the subject matter or materials discussed in the manuscript	have no relevant affiliations or financial conflict with the subject matter or materials discussed in the manuscript	-	-	NO
6289932	30539323	AD	2	finalized the manuscript and were involved in the treatment of the patient and data acquisition	finalized the manuscript and were involved in the treatment of the patient and data acquisition	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
6289932	30539323	CK	2	finalized the manuscript and were involved in the treatment of the patient and data acquisition	finalized the manuscript and were involved in the treatment of the patient and data acquisition	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
6289932	30539323	JH	2	carried out the statistical analysis and wrote the manuscript draft	carried out the statistical analysis and wrote the manuscript draft	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6289932	30539323	LVH	2	carried out the statistical analysis and wrote the manuscript draft	carried out the statistical analysis and wrote the manuscript draft	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6289932	30539323	MD	2	finalized the manuscript and were involved in the treatment of the patient and data acquisition	finalized the manuscript and were involved in the treatment of the patient and data acquisition	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
6289932	30539323	MS	2	finalized the manuscript and were involved in the treatment of the patient and data acquisition	finalized the manuscript and were involved in the treatment of the patient and data acquisition	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5379536	28376718	CB	2	designed and maintain infrastructure and services of bioinformatics which enable the development of the software	designed and maintain infrastructure and services of bioinformatics which enable the development of the software	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Formal analysis|Software	YES
5379536	28376718	FT	2	provided whole-organ profiling and qrt-pcr data	provided whole-organ profiling and qrt-pcr data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5379536	28376718	GS	2	contributed to the software testing and documentation and setup the website|extensively tested the software	contributed to the software testing and documentation and setup the website	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5379536	28376718	GS	2	contributed to the software testing and documentation and setup the website|extensively tested the software	extensively tested the software	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5379536	28376718	JDZ	2	conceived the study|implemented the software, performed simulation studies and wrote the manuscript|extensively tested the software	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5379536	28376718	JDZ	2	conceived the study|implemented the software, performed simulation studies and wrote the manuscript|extensively tested the software	implemented the software, performed simulation studies and wrote the manuscript	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Software|Writing - Original Draft	YES
5379536	28376718	JDZ	2	conceived the study|implemented the software, performed simulation studies and wrote the manuscript|extensively tested the software	extensively tested the software	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5379536	28376718	KH	2	applied bioqc to gtex data and contributed fig|extensively tested the software	applied bioqc to gtex data and contributed fig	-	Visualization	YES
5379536	28376718	KH	2	applied bioqc to gtex data and contributed fig|extensively tested the software	extensively tested the software	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5379536	28376718	LB	2	conceived the study|derived gene signatures from public datasets|extensively tested the software	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5379536	28376718	LB	2	conceived the study|derived gene signatures from public datasets|extensively tested the software	derived gene signatures from public datasets	-	-	NO
5379536	28376718	LB	2	conceived the study|derived gene signatures from public datasets|extensively tested the software	extensively tested the software	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5379536	28376718	MB	2	provided whole-organ profiling and qrt-pcr data	provided whole-organ profiling and qrt-pcr data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5379536	28376718	ME	2	designed and maintain infrastructure and services of bioinformatics which enable the development of the software|extensively tested the software	designed and maintain infrastructure and services of bioinformatics which enable the development of the software	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Formal analysis|Software	YES
5379536	28376718	ME	2	designed and maintain infrastructure and services of bioinformatics which enable the development of the software|extensively tested the software	extensively tested the software	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5379536	28376718	SIP	2	provided whole-organ profiling and qrt-pcr data	provided whole-organ profiling and qrt-pcr data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4408012	25906185	FJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408012	25906185	FJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408012	25906185	FJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408012	25906185	FJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408012	25906185	IH	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408012	25906185	IH	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408012	25906185	MM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Helped in interpretation of results	Analyzed the data	Analyzed the data	Formal analysis	YES
4408012	25906185	MM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Helped in interpretation of results	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408012	25906185	MM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Helped in interpretation of results	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408012	25906185	MM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Helped in interpretation of results	Helped in interpretation of results	Analyzed the data	Formal analysis	YES
4408012	25906185	SD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408012	25906185	SD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408012	25906185	SD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408012	25906185	SD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408012	25906185	SD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408012	25906185	SK	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408012	25906185	SK	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408012	25906185	VK	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408012	25906185	VK	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3996192	24410937	DDL	2	is responsible for the conception, protraction and drawing up of the article	is responsible for the conception, protraction and drawing up of the article	Conceived and designed the experiments	Conceptualization	YES
3996192	24410937	ERT	2	is responsible for the critical revision of the article	is responsible for the critical revision of the article	Wrote the paper	Writing - Review & Editing	YES
3996192	24410937	VLPA	2	is responsible for the drawing up and critical revision of the article	is responsible for the drawing up and critical revision of the article	Wrote the paper	Writing - Review & Editing	YES
6300448	30569328	AP	2	contributed to the preparation of data and dosimetry analysis and manuscript preparation	contributed to the preparation of data and dosimetry analysis and manuscript preparation	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
6300448	30569328	DB	2	contributed to study design and manuscript preparation	contributed to study design and manuscript preparation	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
6300448	30569328	EB	2	gave clinical input in the design of the study and evaluation of results	gave clinical input in the design of the study and evaluation of results	Conceived and designed the experiments	Methodology	YES
6300448	30569328	EE	2	contributed to the preparation of data and dosimetry analysis and manuscript preparation	contributed to the preparation of data and dosimetry analysis and manuscript preparation	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
6300448	30569328	HR	2	contributed to the preparation of data and dosimetry analysis and manuscript preparation	contributed to the preparation of data and dosimetry analysis and manuscript preparation	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
6300448	30569328	KW	2	designed the study and carried out data analysis, including quantification of data, dosimetry, and comparison of methodologies, as well as manuscript preparation	designed the study and carried out data analysis, including quantification of data, dosimetry, and comparison of methodologies, as well as manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5594075	28936223	AC	2	collected the samples|critically revised the article	collected the samples	Performed the experiments	Investigation	YES
5594075	28936223	AC	2	collected the samples|critically revised the article	critically revised the article	Wrote the paper	Writing - Review & Editing	YES
5594075	28936223	BF	2	critically revised the article	critically revised the article	Wrote the paper	Writing - Review & Editing	YES
5594075	28936223	DG	2	collected the samples|critically revised the article	collected the samples	Performed the experiments	Investigation	YES
5594075	28936223	DG	2	collected the samples|critically revised the article	critically revised the article	Wrote the paper	Writing - Review & Editing	YES
5594075	28936223	FF	2	designed the work|critically revised the article	designed the work	Conceived and designed the experiments	-	YES
5594075	28936223	FF	2	designed the work|critically revised the article	critically revised the article	Wrote the paper	Writing - Review & Editing	YES
5594075	28936223	LL	2	collected the samples|critically revised the article	collected the samples	Performed the experiments	Investigation	YES
5594075	28936223	LL	2	collected the samples|critically revised the article	critically revised the article	Wrote the paper	Writing - Review & Editing	YES
5594075	28936223	LR	2	designed the work|critically revised the article	designed the work	Conceived and designed the experiments	-	YES
5594075	28936223	LR	2	designed the work|critically revised the article	critically revised the article	Wrote the paper	Writing - Review & Editing	YES
5594075	28936223	MC	2	designed the work|collected the samples|acquired and analyzed the data|drafted the manuscript	designed the work	Conceived and designed the experiments	-	YES
5594075	28936223	MC	2	designed the work|collected the samples|acquired and analyzed the data|drafted the manuscript	collected the samples	Performed the experiments	Investigation	YES
5594075	28936223	MC	2	designed the work|collected the samples|acquired and analyzed the data|drafted the manuscript	acquired and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5594075	28936223	MC	2	designed the work|collected the samples|acquired and analyzed the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5594075	28936223	MN	2	designed the work|critically revised the article	designed the work	Conceived and designed the experiments	-	YES
5594075	28936223	MN	2	designed the work|critically revised the article	critically revised the article	Wrote the paper	Writing - Review & Editing	YES
5594075	28936223	RSa	2	acquired and analyzed the data|critically revised the article	acquired and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5594075	28936223	RSa	2	acquired and analyzed the data|critically revised the article	critically revised the article	Wrote the paper	Writing - Review & Editing	YES
5594075	28936223	RSe	2	acquired and analyzed the data|critically revised the article	acquired and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5594075	28936223	RSe	2	acquired and analyzed the data|critically revised the article	critically revised the article	Wrote the paper	Writing - Review & Editing	YES
5594075	28936223	RV	2	critically revised the article	critically revised the article	Wrote the paper	Writing - Review & Editing	YES
5594075	28936223	VF	2	collected the samples	collected the samples	Performed the experiments	Investigation	YES
5376926	28409027	Abera Beyamo Mekiso	PLoS52	conceived and designed the experiments|contributed materials/analysis tools|were responsible for writing, reviewing, and editing	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5376926	28409027	Abera Beyamo Mekiso	PLoS52	conceived and designed the experiments|contributed materials/analysis tools|were responsible for writing, reviewing, and editing	contributed materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5376926	28409027	Abera Beyamo Mekiso	PLoS52	conceived and designed the experiments|contributed materials/analysis tools|were responsible for writing, reviewing, and editing	were responsible for writing, reviewing, and editing	Wrote the paper	Writing - Review & Editing	YES
5376926	28409027	Bayu Begashaw	PLoS52	conceived and designed the experiments|contributed materials/analysis tools|were responsible for writing, reviewing, and editing	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5376926	28409027	Bayu Begashaw	PLoS52	conceived and designed the experiments|contributed materials/analysis tools|were responsible for writing, reviewing, and editing	contributed materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5376926	28409027	Bayu Begashaw	PLoS52	conceived and designed the experiments|contributed materials/analysis tools|were responsible for writing, reviewing, and editing	were responsible for writing, reviewing, and editing	Wrote the paper	Writing - Review & Editing	YES
5376926	28409027	Degefa Tadele Belato	PLoS52	conceived and designed the experiments|conducted formal analysis|was responsible for funding acquisition|analyzed the data|contributed materials/analysis tools|wrote original draft|were responsible for writing, reviewing, and editing	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5376926	28409027	Degefa Tadele Belato	PLoS52	conceived and designed the experiments|conducted formal analysis|was responsible for funding acquisition|analyzed the data|contributed materials/analysis tools|wrote original draft|were responsible for writing, reviewing, and editing	conducted formal analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5376926	28409027	Degefa Tadele Belato	PLoS52	conceived and designed the experiments|conducted formal analysis|was responsible for funding acquisition|analyzed the data|contributed materials/analysis tools|wrote original draft|were responsible for writing, reviewing, and editing	was responsible for funding acquisition	-	Funding acquisition	YES
5376926	28409027	Degefa Tadele Belato	PLoS52	conceived and designed the experiments|conducted formal analysis|was responsible for funding acquisition|analyzed the data|contributed materials/analysis tools|wrote original draft|were responsible for writing, reviewing, and editing	analyzed the data	Analyzed the data	Formal analysis	YES
5376926	28409027	Degefa Tadele Belato	PLoS52	conceived and designed the experiments|conducted formal analysis|was responsible for funding acquisition|analyzed the data|contributed materials/analysis tools|wrote original draft|were responsible for writing, reviewing, and editing	contributed materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5376926	28409027	Degefa Tadele Belato	PLoS52	conceived and designed the experiments|conducted formal analysis|was responsible for funding acquisition|analyzed the data|contributed materials/analysis tools|wrote original draft|were responsible for writing, reviewing, and editing	wrote original draft	Wrote the paper	Writing - Original Draft	YES
5376926	28409027	Degefa Tadele Belato	PLoS52	conceived and designed the experiments|conducted formal analysis|was responsible for funding acquisition|analyzed the data|contributed materials/analysis tools|wrote original draft|were responsible for writing, reviewing, and editing	were responsible for writing, reviewing, and editing	Wrote the paper	Writing - Review & Editing	YES
4408013	25906140	GC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408013	25906140	GC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408013	25906140	GC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408013	25906140	GS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408013	25906140	GS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408013	25906140	JT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408013	25906140	JT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408013	25906140	JT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408013	25906140	JT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408013	25906140	LA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408013	25906140	LA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408013	25906140	LA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408013	25906140	LCN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408013	25906140	LCN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408013	25906140	LCN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408013	25906140	LCN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408013	25906140	PR	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408013	25906140	PR	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408013	25906140	PR	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5379614	28376774	DG	2	conceived the project	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5379614	28376774	DJ	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5379614	28376774	MS	2	conceived the project|designed and carried out bioinformatics analysis and web server construction|wrote the manuscript	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5379614	28376774	MS	2	conceived the project|designed and carried out bioinformatics analysis and web server construction|wrote the manuscript	designed and carried out bioinformatics analysis and web server construction	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Software	YES
5379614	28376774	MS	2	conceived the project|designed and carried out bioinformatics analysis and web server construction|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5379614	28376774	QZ	2	designed and carried out bioinformatics analysis and web server construction	designed and carried out bioinformatics analysis and web server construction	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Software	YES
5379614	28376774	WG	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5379614	28376774	YW	2	designed and carried out bioinformatics analysis and web server construction	designed and carried out bioinformatics analysis and web server construction	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Software	YES
5379614	28376774	YX	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4017084	24884923	All authors	2	contributed equally	contributed equally	-	-	NO
6300454	30569426	All authors	2	reviewed and agreed to the manuscript content	reviewed and agreed to the manuscript content	Wrote the paper	Writing - Review & Editing	YES
6300454	30569426	HI	2	participated in the design, managed the study, designed the technique, and drafted the manuscript	participated in the design, managed the study, designed the technique, and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft	YES
6300454	30569426	JN	2	participated in design, patient recruitment, and edited the manuscript	participated in design, patient recruitment, and edited the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
6300454	30569426	JT	2	participated in the design and edited the manuscript|participated in design, patient recruitment, and edited the manuscript	participated in the design and edited the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Review & Editing	YES
6300454	30569426	JT	2	participated in the design and edited the manuscript|participated in design, patient recruitment, and edited the manuscript	participated in design, patient recruitment, and edited the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
6300454	30569426	KK	2	participated in the design, created the system, optimized the technique, created the program, analyzed the results, and edited the manuscript	participated in the design, created the system, optimized the technique, created the program, analyzed the results, and edited the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
6300454	30569426	KT	2	participated in the design and edited the manuscript	participated in the design and edited the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Review & Editing	YES
6300454	30569426	MY	2	participated in the design, created the system, optimized the technique, created the program, analyzed the results, and edited the manuscript	participated in the design, created the system, optimized the technique, created the program, analyzed the results, and edited the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
6300454	30569426	SI	2	participated in the design, created the program, implemented the analysis, and drafted the manuscript	participated in the design, created the program, implemented the analysis, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6300454	30569426	SK	2	participated in the design and edited the manuscript	participated in the design and edited the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Review & Editing	YES
6300454	30569426	SS	2	participated in the design and edited the manuscript	participated in the design and edited the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Review & Editing	YES
6300454	30569426	TF	2	participated in design, patient recruitment, and edited the manuscript	participated in design, patient recruitment, and edited the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
6300454	30569426	TM	2	participated in the design, created the system, optimized the technique, created the program, analyzed the results, and edited the manuscript	participated in the design, created the system, optimized the technique, created the program, analyzed the results, and edited the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
6300454	30569426	YH	2	participated in the design, created the system, optimized the technique, created the program, analyzed the results, and edited the manuscript	participated in the design, created the system, optimized the technique, created the program, analyzed the results, and edited the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
6300454	30569426	YT	2	participated in the data collection and image processing	participated in the data collection and image processing	Performed the experiments|Analyzed the data	Data curation|Investigation|Visualization	YES
5594086	28936221	FZ	2	designed the project	designed the project	Conceived and designed the experiments	Methodology	YES
5594086	28936221	GZ	2	designed the project	designed the project	Conceived and designed the experiments	Methodology	YES
5594086	28936221	KC	2	carried out the experimental work	carried out the experimental work	Performed the experiments	Investigation	YES
5594086	28936221	XW	2	carried out the experimental work	carried out the experimental work	Performed the experiments	Investigation	YES
5594086	28936221	all authors	2	read and approved the paper	read and approved the paper	-	-	NO
6323062	30617816	All authors	2	critically revised and approved the final manuscript	critically revised and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6323062	30617816	GF	2	conceived of and designed the study	conceived of and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6323062	30617816	JG	2	conceived of and designed the study|carried out the experiments|analysed and interpreted the data|drafted the manuscript	conceived of and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6323062	30617816	JG	2	conceived of and designed the study|carried out the experiments|analysed and interpreted the data|drafted the manuscript	carried out the experiments	Performed the experiments	Investigation	YES
6323062	30617816	JG	2	conceived of and designed the study|carried out the experiments|analysed and interpreted the data|drafted the manuscript	analysed and interpreted the data	Analyzed the data	Formal analysis	YES
6323062	30617816	JG	2	conceived of and designed the study|carried out the experiments|analysed and interpreted the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
6323062	30617816	JT	2	carried out the experiments|analysed and interpreted the data	carried out the experiments	Performed the experiments	Investigation	YES
6323062	30617816	JT	2	carried out the experiments|analysed and interpreted the data	analysed and interpreted the data	Analyzed the data	Formal analysis	YES
6323062	30617816	OW	2	carried out the experiments|analysed and interpreted the data	carried out the experiments	Performed the experiments	Investigation	YES
6323062	30617816	OW	2	carried out the experiments|analysed and interpreted the data	analysed and interpreted the data	Analyzed the data	Formal analysis	YES
4408014	25906070	BCR	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4408014	25906070	GP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408014	25906070	GP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408014	25906070	GP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408014	25906070	GP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408014	25906070	JMR	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4408014	25906070	JMR	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4408014	25906070	KDS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408014	25906070	KDS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408014	25906070	LK	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408014	25906070	LK	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4029305	24314027	All authors	2	contributed to the development of the interview guide, discussions of emerging findings from the interviews, and revisions to the information sheet	contributed to the development of the interview guide, discussions of emerging findings from the interviews, and revisions to the information sheet	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4029305	24314027	JS	2	conducted 1 interview|reviewed and approved the final manuscript	conducted 1 interview	Performed the experiments	Investigation	YES
4029305	24314027	JS	2	conducted 1 interview|reviewed and approved the final manuscript	reviewed and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4029305	24314027	KA	2	reviewed all interview transcripts and the remaining authors reviewed 6 transcripts each|wrote the manuscript with input from all other authors	reviewed all interview transcripts and the remaining authors reviewed 6 transcripts each	Performed the experiments	Investigation	YES
4029305	24314027	KA	2	reviewed all interview transcripts and the remaining authors reviewed 6 transcripts each|wrote the manuscript with input from all other authors	wrote the manuscript with input from all other authors	Wrote the paper	Writing - Original Draft	YES
4029305	24314027	VAC	2	reviewed and approved the final manuscript	reviewed and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5379710	28376793	CMcQ	2	led the laboratory components of the work	led the laboratory components of the work	Performed the experiments	Investigation	YES
5379710	28376793	COF	2	conceived and designed the experiments, analysed the data and wrote the manuscript	conceived and designed the experiments, analysed the data and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
5379710	28376793	EF	2	carried out additional bioinformatics analysis	carried out additional bioinformatics analysis	Performed the experiments	Formal analysis|Investigation	YES
5379710	28376793	KM	2	conceived and designed the experiments, analysed the data and wrote the manuscript	conceived and designed the experiments, analysed the data and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
5379710	28376793	SF	2	conceived and designed the experiments, analysed the data and wrote the manuscript	conceived and designed the experiments, analysed the data and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
5379710	28376793	TH	2	carried out the bioinformatics analysis, analysed the data and wrote the manuscript	carried out the bioinformatics analysis, analysed the data and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5577684	28782334	JS	2	conceptualized the article	conceptualized the article	Conceived and designed the experiments	Conceptualization	YES
5577684	28782334	SM	2	conceptualized the article	conceptualized the article	Conceived and designed the experiments	Conceptualization	YES
5577684	28782334	TC	2	conceptualized the article	conceptualized the article	Conceived and designed the experiments	Conceptualization	YES
4529902	26273620	Andre Di Nanni	2	contributed equally	contributed equally	-	-	NO
4529902	26273620	Imeke Goldschmidt	2	contributed equally	contributed equally	-	-	NO
5594091	28936215	A-J	2	was involved in revising the manuscript critically for important intellectual content	was involved in revising the manuscript critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5594091	28936215	AS	2	was involved in revising the manuscript critically for important intellectual content	was involved in revising the manuscript critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5594091	28936215	All authors	2	contributed, read and approved the final manuscript	contributed, read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5594091	28936215	M-R	2	contributed, read and approved the final manuscript	contributed, read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5594091	28936215	PA-J	2	made the final approval	made the final approval	-	-	NO
5392405	28469942	All authors	2	have reviewed and approved the manuscript	have reviewed and approved the manuscript	Wrote the paper	Writing - Review & Editing	YES
5392405	28469942	Barbara Castelnuovo	2	overall supervised the study and reviewed the manuscript	overall supervised the study and reviewed the manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
6326913	30627803	AK	2	contributed to the drafting of the manuscript	contributed to the drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
6326913	30627803	CK	2	contributed to the drafting of the manuscript	contributed to the drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
6326913	30627803	CRS	2	contributed to the drafting of the manuscript	contributed to the drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
4047256	24888748	JLV	2	attest that they have made substantial contributions in drafting the manuscript and revising it critically for important intellectual content, that they have given final approval of the version to be published, and that they have participated sufficiently in the work to take public responsibility for appropriate portions of the content|have read and approved the final manuscript	attest that they have made substantial contributions in drafting the manuscript and revising it critically for important intellectual content, that they have given final approval of the version to be published, and that they have participated sufficiently in the work to take public responsibility for appropriate portions of the content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4047256	24888748	JLV	2	attest that they have made substantial contributions in drafting the manuscript and revising it critically for important intellectual content, that they have given final approval of the version to be published, and that they have participated sufficiently in the work to take public responsibility for appropriate portions of the content|have read and approved the final manuscript	have read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4047256	24888748	MYR	2	attest that they have made substantial contributions in drafting the manuscript and revising it critically for important intellectual content, that they have given final approval of the version to be published, and that they have participated sufficiently in the work to take public responsibility for appropriate portions of the content|have read and approved the final manuscript	attest that they have made substantial contributions in drafting the manuscript and revising it critically for important intellectual content, that they have given final approval of the version to be published, and that they have participated sufficiently in the work to take public responsibility for appropriate portions of the content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4047256	24888748	MYR	2	attest that they have made substantial contributions in drafting the manuscript and revising it critically for important intellectual content, that they have given final approval of the version to be published, and that they have participated sufficiently in the work to take public responsibility for appropriate portions of the content|have read and approved the final manuscript	have read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4408020	25905778	GS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408020	25905778	GS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408020	25905778	GS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408020	25905778	GS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408020	25905778	GS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408020	25905778	MBP	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4408020	25905778	MBP	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4408020	25905778	MCB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408020	25905778	MCB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408020	25905778	MCB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4529903	26273615	All authors	2	have given final approval of the last version	have given final approval of the last version	-	-	NO
4529903	26273615	Furkan Erol Karabekmez	2	have made substantial contributions to conception and design of the study|have been involved in drafting the paper	have made substantial contributions to conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4529903	26273615	Furkan Erol Karabekmez	2	have made substantial contributions to conception and design of the study|have been involved in drafting the paper	have been involved in drafting the paper	Wrote the paper	Writing - Original Draft	YES
4529903	26273615	Johannes Kleinheinz	2	have made substantial contributions to conception and design of the study|have been involved in drafting the paper	have made substantial contributions to conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4529903	26273615	Johannes Kleinheinz	2	have made substantial contributions to conception and design of the study|have been involved in drafting the paper	have been involved in drafting the paper	Wrote the paper	Writing - Original Draft	YES
4529903	26273615	Susanne Jung	2	have made substantial contributions to conception and design of the study|have been involved in drafting the paper	have made substantial contributions to conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4529903	26273615	Susanne Jung	2	have made substantial contributions to conception and design of the study|have been involved in drafting the paper	have been involved in drafting the paper	Wrote the paper	Writing - Original Draft	YES
6328430	30631980	AW	2	were responsible for the study concept and design|informed and recruited all participants	were responsible for the study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6328430	30631980	AW	2	were responsible for the study concept and design|informed and recruited all participants	informed and recruited all participants	Performed the experiments	Investigation	YES
6328430	30631980	CT	2	protocol and the activity measurement of urine and blood	protocol and the activity measurement of urine and blood	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6328430	30631980	JA	2	were responsible for the study concept and design	were responsible for the study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6328430	30631980	JHJ	2	were responsible for the technical support, data interpretation, and critical review of the manuscript	were responsible for the technical support, data interpretation, and critical review of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
6328430	30631980	KR	2	were responsible for the study concept and design	were responsible for the study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6328430	30631980	LJ	2	performed the calculations	performed the calculations	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6328430	30631980	MA	2	performed the monte carlo simulations	performed the monte carlo simulations	Performed the experiments	Formal analysis|Investigation	YES
6328430	30631980	MO	2	carried out the radiochemistry|were responsible for the study concept and design	carried out the radiochemistry	Performed the experiments	Investigation	YES
6328430	30631980	MO	2	carried out the radiochemistry|were responsible for the study concept and design	were responsible for the study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6328430	30631980	MgO	2	carried out the radiochemistry	carried out the radiochemistry	Performed the experiments	Investigation	YES
6328430	30631980	TN	2	were responsible for the technical support, data interpretation, and critical review of the manuscript	were responsible for the technical support, data interpretation, and critical review of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
5420412	28512582	Kelemu Dessie Bizuneh	2	designed the study and collected data|performed analysis and wrote the manuscript	designed the study and collected data	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5420412	28512582	Kelemu Dessie Bizuneh	2	designed the study and collected data|performed analysis and wrote the manuscript	performed analysis and wrote the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5420412	28512582	Mulusew Alemneh Sinishaw	2	performed analysis and wrote the manuscript	performed analysis and wrote the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5420412	28512582	Woudneh Gereme Desta	2	designed the study and collected data|performed analysis and wrote the manuscript	designed the study and collected data	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5420412	28512582	Woudneh Gereme Desta	2	designed the study and collected data|performed analysis and wrote the manuscript	performed analysis and wrote the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5379729	28376762	CS	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5379729	28376762	CW	PLoS52	conceived and designed the project|analyzed the data|wrote the manuscript	conceived and designed the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5379729	28376762	CW	PLoS52	conceived and designed the project|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5379729	28376762	CW	PLoS52	conceived and designed the project|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5379729	28376762	LT	PLoS52	implemented and tested the system|analyzed the data|wrote the manuscript	implemented and tested the system	Performed the experiments	Investigation	YES
5379729	28376762	LT	PLoS52	implemented and tested the system|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5379729	28376762	LT	PLoS52	implemented and tested the system|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5379729	28376762	NH	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5379729	28376762	WH	PLoS52	implemented and tested the system|analyzed the data|wrote the manuscript	implemented and tested the system	Performed the experiments	Investigation	YES
5379729	28376762	WH	PLoS52	implemented and tested the system|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5379729	28376762	WH	PLoS52	implemented and tested the system|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5379729	28376762	YL	PLoS52	implemented and tested the system|analyzed the data|wrote the manuscript	implemented and tested the system	Performed the experiments	Investigation	YES
5379729	28376762	YL	PLoS52	implemented and tested the system|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5379729	28376762	YL	PLoS52	implemented and tested the system|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5594102	28936218	AG	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5594102	28936218	HJ	PLoS52	designed the research|analyzed the data	designed the research	Conceived and designed the experiments	Methodology	YES
5594102	28936218	HJ	PLoS52	designed the research|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5594102	28936218	IM	PLoS52	designed the research|performed the experiments|analyzed the data	designed the research	Conceived and designed the experiments	Methodology	YES
5594102	28936218	IM	PLoS52	designed the research|performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5594102	28936218	IM	PLoS52	designed the research|performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5594102	28936218	MH-C	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5594102	28936218	MH-C	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5594102	28936218	MK	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5594102	28936218	MK	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5594102	28936218	RS-B	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5594102	28936218	RS-B	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
4047768	24885037	All authors	2	contributed to study concept|were involved in, and have given final approval of the version of the manuscript to be published	contributed to study concept	Conceived and designed the experiments	Conceptualization	YES
4047768	24885037	All authors	2	contributed to study concept|were involved in, and have given final approval of the version of the manuscript to be published	were involved in, and have given final approval of the version of the manuscript to be published	-	-	NO
4047768	24885037	JG	2	was responsible for study design, data interpretation, and developing, revising and critical review of the manuscript	was responsible for study design, data interpretation, and developing, revising and critical review of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
4047768	24885037	LB	2	were responsible for data collection, interpretation, and manuscript preparation	were responsible for data collection, interpretation, and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4047768	24885037	MD	2	were responsible for data collection, interpretation, and manuscript preparation	were responsible for data collection, interpretation, and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4408021	25906254	CO	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408021	25906254	CO	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4408021	25906254	CO	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4408021	25906254	EM	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4408021	25906254	EM	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4408021	25906254	JI	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4408021	25906254	JI	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4408021	25906254	KK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408021	25906254	KK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4408021	25906254	KK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4408021	25906254	KK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4408021	25906254	MO	PLoS5	Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5577690	28361505	All authors	2	reviewed and approved the final manuscript	reviewed and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5577690	28361505	RF	2	was the principal author of the first draft of the article	was the principal author of the first draft of the article	Wrote the paper	Writing - Original Draft	YES
6399365	30830530	All authors	2	agree to be accountable for this work	agree to be accountable for this work	-	-	NO
6399365	30830530	JD	2	conceived and was the primary author of the paper	conceived and was the primary author of the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
6399365	30830530	SR	2	were involved in the drafting and revision of the manuscript and gave their final approval for the paper to be published	were involved in the drafting and revision of the manuscript and gave their final approval for the paper to be published	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6399365	30830530	SV	2	were involved in the drafting and revision of the manuscript and gave their final approval for the paper to be published	were involved in the drafting and revision of the manuscript and gave their final approval for the paper to be published	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5594104	28936222	HZ	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5379732	28372538	BO	2	performed the bioinformatics analyses	performed the bioinformatics analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5379732	28372538	JH	2	carried out the experiments|conceived, designed and coordinated the study|drafted the manuscript	carried out the experiments	Performed the experiments	Investigation	YES
5379732	28372538	JH	2	carried out the experiments|conceived, designed and coordinated the study|drafted the manuscript	conceived, designed and coordinated the study	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
5379732	28372538	JH	2	carried out the experiments|conceived, designed and coordinated the study|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5379732	28372538	PT	2	conceived, designed and coordinated the study|drafted the manuscript	conceived, designed and coordinated the study	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
5379732	28372538	PT	2	conceived, designed and coordinated the study|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5379732	28372538	SK	2	carried out the experiments|drafted the manuscript	carried out the experiments	Performed the experiments	Investigation	YES
5379732	28372538	SK	2	carried out the experiments|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5379732	28372538	SS	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5379732	28372538	TS	2	enabled the access to the rye genome and supported data handling	enabled the access to the rye genome and supported data handling	-	Data curation	YES
5468550	28638661	Adane Teshome Kefale	2	did article searching, critical appraisal, data extraction, and data analysis and edited manuscript	did article searching, critical appraisal, data extraction, and data analysis and edited manuscript	Analyzed the data|Wrote the paper	Data curation|Formal analysis|Writing - Review & Editing	YES
5468550	28638661	Habtamu Acho Addo	2	did article searching, critical appraisal, data extraction, and data analysis and edited manuscript	did article searching, critical appraisal, data extraction, and data analysis and edited manuscript	Analyzed the data|Wrote the paper	Data curation|Formal analysis|Writing - Review & Editing	YES
5468550	28638661	Muktar Sano Kedir	2	did article searching, critical appraisal, data extraction, and data analysis and developed manuscript	did article searching, critical appraisal, data extraction, and data analysis and developed manuscript	Analyzed the data|Wrote the paper	Data curation|Formal analysis|Writing - Original Draft	YES
5468550	28638661	Tegene Legese Dadi	2	did article searching, critical appraisal, data extraction, and data analysis and edited manuscript	did article searching, critical appraisal, data extraction, and data analysis and edited manuscript	Analyzed the data|Wrote the paper	Data curation|Formal analysis|Writing - Review & Editing	YES
5468550	28638661	Teshale Ayele Mega	2	did article searching, critical appraisal, data extraction, and data analysis and developed manuscript	did article searching, critical appraisal, data extraction, and data analysis and developed manuscript	Analyzed the data|Wrote the paper	Data curation|Formal analysis|Writing - Original Draft	YES
5468550	28638661	Tessema Tsehay Biru	2	did article searching, critical appraisal, and data extraction	did article searching, critical appraisal, and data extraction	Analyzed the data	Data curation	YES
6428870	30900064	All authors	2	participated in the design of the study	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
6428870	30900064	DM	2	participated in the data analysis	participated in the data analysis	Analyzed the data	Formal analysis	YES
6428870	30900064	ET	2	participated in the data analysis	participated in the data analysis	Analyzed the data	Formal analysis	YES
6428870	30900064	HA	2	interpreted the images	interpreted the images	Analyzed the data	Formal analysis|Visualization	YES
6428870	30900064	JO	2	participated in the data analysis	participated in the data analysis	Analyzed the data	Formal analysis	YES
6428870	30900064	MB	2	participated in the data analysis|wrote the manuscript, and the other authors revised the manuscript	participated in the data analysis	Analyzed the data	Formal analysis	YES
6428870	30900064	MB	2	participated in the data analysis|wrote the manuscript, and the other authors revised the manuscript	wrote the manuscript, and the other authors revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6428870	30900064	NKB	2	interpreted the images	interpreted the images	Analyzed the data	Formal analysis|Visualization	YES
5577691	28853518	AC	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5577691	28853518	AP	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5577691	28853518	All the authors	2	interpreted data|provided input into the report, revised it critically for important intellectual content and approved the final version of the report	interpreted data	Analyzed the data	Formal analysis	YES
5577691	28853518	All the authors	2	interpreted data|provided input into the report, revised it critically for important intellectual content and approved the final version of the report	provided input into the report, revised it critically for important intellectual content and approved the final version of the report	Wrote the paper	Writing - Review & Editing	YES
5577691	28853518	CS	2	designed the study|drafted the report	designed the study	Conceived and designed the experiments	Methodology	YES
5577691	28853518	CS	2	designed the study|drafted the report	drafted the report	Wrote the paper	Writing - Original Draft	YES
5577691	28853518	FL	2	designed the study|drafted the report	designed the study	Conceived and designed the experiments	Methodology	YES
5577691	28853518	FL	2	designed the study|drafted the report	drafted the report	Wrote the paper	Writing - Original Draft	YES
5577691	28853518	NB	2	designed the study|did the statistical analysis|drafted the report	designed the study	Conceived and designed the experiments	Methodology	YES
5577691	28853518	NB	2	designed the study|did the statistical analysis|drafted the report	did the statistical analysis	Analyzed the data	Formal analysis	YES
5577691	28853518	NB	2	designed the study|did the statistical analysis|drafted the report	drafted the report	Wrote the paper	Writing - Original Draft	YES
4121306	25033795	AL	2	revised each version	revised each version	Wrote the paper	Writing - Review & Editing	YES
4121306	25033795	PC	2	revised each version	revised each version	Wrote the paper	Writing - Review & Editing	YES
4121306	25033795	TL	2	drafted the first versions of this paper, and provided the technical backgrounds and expertise	drafted the first versions of this paper, and provided the technical backgrounds and expertise	Wrote the paper	Writing - Original Draft	YES
4408022	25906048	BLB	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408022	25906048	LWM	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408022	25906048	LWM	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408022	25906048	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408022	25906048	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408022	25906048	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408022	25906048	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408022	25906048	RS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408022	25906048	RS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408022	25906048	RS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408022	25906048	RS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5594215	28936217	AG	2	designed the experiment, coordinated the work, interpreted data and wrote the manuscript	designed the experiment, coordinated the work, interpreted data and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Project administration|Writing - Original Draft	YES
5594215	28936217	DK	2	helped in soil analysis	helped in soil analysis	-	-	NO
5594215	28936217	HT	2	helped in the photosynthesis data and plant analysis	helped in the photosynthesis data and plant analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5594215	28936217	KA	2	helped in soil analysis|helped in data interpretation and critically reviewed the manuscript	helped in soil analysis	-	-	NO
5594215	28936217	KA	2	helped in soil analysis|helped in data interpretation and critically reviewed the manuscript	helped in data interpretation and critically reviewed the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5594215	28936217	KG	2	prepared characterized and provided the fertilizers	prepared characterized and provided the fertilizers	Performed the experiments	Investigation	YES
5594215	28936217	KT	2	performed experimental work, analyzed and interpreted data and wrote the manuscript	performed experimental work, analyzed and interpreted data and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5594215	28936217	PM	2	prepared characterized and provided the fertilizers	prepared characterized and provided the fertilizers	Performed the experiments	Investigation	YES
5594215	28936217	RK	2	helped in the photosynthesis data and plant analysis	helped in the photosynthesis data and plant analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5824694	29503845	CT	2	image acquisition	image acquisition	Analyzed the data	Visualization	YES
5824694	29503845	FB	2	conceived and designed the complete study	conceived and designed the complete study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5824694	29503845	KSL	2	conceived and designed the complete study	conceived and designed the complete study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5824694	29503845	ZZ	2	was responsible for chemical synthesis and quality control of cold standards and radiotracers	was responsible for chemical synthesis and quality control of cold standards and radiotracers	Performed the experiments	Validation	YES
5474550	28656105	Alemayehu Bekele	2	assisted in the conception, design, and interpretation of results and drafting the manuscript	assisted in the conception, design, and interpretation of results and drafting the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
5474550	28656105	Alemayehu Shimeka	2	assisted in the conception and design of the study and helped in writing the proposal, developing tools, performing the analysis, and writing the paper|has also developed the manuscript	assisted in the conception and design of the study and helped in writing the proposal, developing tools, performing the analysis, and writing the paper	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Writing - Original Draft	YES
5474550	28656105	Alemayehu Shimeka	2	assisted in the conception and design of the study and helped in writing the proposal, developing tools, performing the analysis, and writing the paper|has also developed the manuscript	has also developed the manuscript	Wrote the paper	Writing - Original Draft	YES
5474550	28656105	Maru Meseret	2	conceptualized and designed the study, developed tools, supervised data collection, performed analysis and interpretation of data, and drafted the paper	conceptualized and designed the study, developed tools, supervised data collection, performed analysis and interpretation of data, and drafted the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Supervision|Writing - Original Draft	YES
5379770	28376721	DL	2	prepared dna	prepared dna	-	-	NO
5379770	28376721	GF	2	wrote the manuscript|prepared dna	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5379770	28376721	GF	2	wrote the manuscript|prepared dna	prepared dna	-	-	NO
5379770	28376721	WQ	2	established the mapping population and designed the entire project|wrote the manuscript	established the mapping population and designed the entire project	Conceived and designed the experiments	Methodology	YES
5379770	28376721	WQ	2	established the mapping population and designed the entire project|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5379770	28376721	ZX	2	established the mapping population and designed the entire project	established the mapping population and designed the entire project	Conceived and designed the experiments	Methodology	YES
4136633	25115172	AV	2	recruited patients and administered survey instruments	recruited patients and administered survey instruments	Performed the experiments	Investigation	YES
4136633	25115172	CA	2	recruited patients and administered survey instruments	recruited patients and administered survey instruments	Performed the experiments	Investigation	YES
4136633	25115172	ED	2	addressed the ethical and legal aspects and helped draft the manuscript	addressed the ethical and legal aspects and helped draft the manuscript	Wrote the paper	Writing - Original Draft	YES
4136633	25115172	EP	2	recruited patients and administered survey instruments	recruited patients and administered survey instruments	Performed the experiments	Investigation	YES
4136633	25115172	FD	2	addressed the ethical aspects	addressed the ethical aspects	-	-	NO
4136633	25115172	FE	2	coordinated data analysis and interpretation	coordinated data analysis and interpretation	Analyzed the data	Formal analysis|Project administration	YES
4136633	25115172	GC	2	designed and coordinated the study, interpreted data and wrote the first draft	designed and coordinated the study, interpreted data and wrote the first draft	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Project administration|Writing - Original Draft	YES
4136633	25115172	GLN	2	designed and coordinated the study, interpreted data and wrote the first draft	designed and coordinated the study, interpreted data and wrote the first draft	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Project administration|Writing - Original Draft	YES
4136633	25115172	GSC	2	coordinated data analysis and interpretation	coordinated data analysis and interpretation	Analyzed the data	Formal analysis|Project administration	YES
4136633	25115172	MGO	2	recruited patients and administered survey instruments	recruited patients and administered survey instruments	Performed the experiments	Investigation	YES
4136633	25115172	MP	2	addressed the legal aspects	addressed the legal aspects	-	-	NO
4136633	25115172	MRP	2	addressed the legal aspects	addressed the legal aspects	-	-	NO
4136633	25115172	RD	2	addressed the legal aspects	addressed the legal aspects	-	-	NO
4136633	25115172	RL	2	recruited patients and administered survey instruments	recruited patients and administered survey instruments	Performed the experiments	Investigation	YES
4136633	25115172	SP	2	addressed the ethical aspects and wrote the last version of the manuscript	addressed the ethical aspects and wrote the last version of the manuscript	Wrote the paper	Writing - Original Draft	YES
5577693	28361506	All authors	2	contributed towards the development, writing and editing of this commentary	contributed towards the development, writing and editing of this commentary	Wrote the paper	Writing - Review & Editing	YES
5577693	28361506	DC	2	contributed towards the development, writing and editing of this commentary	contributed towards the development, writing and editing of this commentary	Wrote the paper	Writing - Review & Editing	YES
5577693	28361506	LTM	2	contributed towards the development, writing and editing of this commentary	contributed towards the development, writing and editing of this commentary	Wrote the paper	Writing - Review & Editing	YES
5577693	28361506	ND	2	contributed towards the development, writing and editing of this commentary	contributed towards the development, writing and editing of this commentary	Wrote the paper	Writing - Review & Editing	YES
5577693	28361506	SRS	2	contributed towards the development, writing and editing of this commentary	contributed towards the development, writing and editing of this commentary	Wrote the paper	Writing - Review & Editing	YES
5577693	28361506	TLC	2	contributed towards the development, writing and editing of this commentary	contributed towards the development, writing and editing of this commentary	Wrote the paper	Writing - Review & Editing	YES
4408024	25905447	ES	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408024	25905447	ES	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408024	25905447	ES	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408024	25905447	ES	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408024	25905447	IL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408024	25905447	IL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408024	25905447	IL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408024	25905447	IL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408024	25905447	KS	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408024	25905447	MG	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408024	25905447	MG	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4408024	25905447	MS	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408024	25905447	PS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408024	25905447	PS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408024	25905447	RD	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408024	25905447	TB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4408024	25905447	TG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4408024	25905447	TG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408024	25905447	UC	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5824695	29503848	AFB	2	conducted the laboratory work	conducted the laboratory work	Performed the experiments	Investigation	YES
5824695	29503848	AVM	2	conducted the laboratory work	conducted the laboratory work	Performed the experiments	Investigation	YES
5824695	29503848	BDH	2	conducted the laboratory work	conducted the laboratory work	Performed the experiments	Investigation	YES
5824695	29503848	BGH	2	provided quality assurance and regulatory oversight	provided quality assurance and regulatory oversight	Performed the experiments	Supervision|Validation	YES
5824695	29503848	KAF	2	conceived and designed experiments	conceived and designed experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5824695	29503848	PJHS	2	conceived and designed experiments	conceived and designed experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5824695	29503848	all authors	2	analyzed data and wrote the manuscript	analyzed data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5382486	28381255	AD	2	carried out dna methylation experiments	carried out dna methylation experiments	Performed the experiments	Investigation	YES
5382486	28381255	HK	2	conceived the study and participated in the design of experiments and drafting of the manuscript	conceived the study and participated in the design of experiments and drafting of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Writing - Original Draft	YES
5382486	28381255	HN	2	carried out dna methylation experiments	carried out dna methylation experiments	Performed the experiments	Investigation	YES
5382486	28381255	JC	2	carried out dna methylation experiments	carried out dna methylation experiments	Performed the experiments	Investigation	YES
5382486	28381255	JK	2	participated in the design of experiments and carried out the experiments, data analysis and drafting of the manuscript	participated in the design of experiments and carried out the experiments, data analysis and drafting of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5382486	28381255	JS	2	participated in dna methylation analysis	participated in dna methylation analysis	-	-	NO
5382486	28381255	SMS	2	participated in the conception of the study and editing of the manuscript	participated in the conception of the study and editing of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5594218	28936219	CC	2	designed the experiments, pipelines of bioinformatics, created the mapping population and wrote the manuscript	designed the experiments, pipelines of bioinformatics, created the mapping population and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5594218	28936219	LP	2	designed the experiments, pipelines of bioinformatics, created the mapping population and wrote the manuscript	designed the experiments, pipelines of bioinformatics, created the mapping population and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5594218	28936219	NW	2	performed the bioinformatics analyses	performed the bioinformatics analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5594218	28936219	QX	2	performed the restriction-site associated dna sequencing experiments	performed the restriction-site associated dna sequencing experiments	Performed the experiments	Investigation	YES
5594218	28936219	RG	2	planted the experimental materials and collected the phenotypic data	planted the experimental materials and collected the phenotypic data	Performed the experiments	Investigation	YES
5594218	28936219	SG	2	performed the bioinformatics analyses	performed the bioinformatics analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5594218	28936219	XY	2	planted the experimental materials and collected the phenotypic data|performed the restriction-site associated dna sequencing experiments	planted the experimental materials and collected the phenotypic data	Performed the experiments	Investigation	YES
5594218	28936219	XY	2	planted the experimental materials and collected the phenotypic data|performed the restriction-site associated dna sequencing experiments	performed the restriction-site associated dna sequencing experiments	Performed the experiments	Investigation	YES
5594218	28936219	YZ	2	performed the restriction-site associated dna sequencing experiments	performed the restriction-site associated dna sequencing experiments	Performed the experiments	Investigation	YES
5594218	28936219	ZW	2	performed the bioinformatics analyses	performed the bioinformatics analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4226210	24207065	BV	2	is responsible for the full content of the manuscript	is responsible for the full content of the manuscript	-	-	NO
4408025	25906046	CH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408025	25906046	CH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408025	25906046	CH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408025	25906046	EP	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408025	25906046	EP	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408025	25906046	EP	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408025	25906046	FM	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408025	25906046	FM	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408025	25906046	FP	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408025	25906046	FP	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408025	25906046	FP	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408025	25906046	IM	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408025	25906046	IM	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408025	25906046	JE	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408025	25906046	JE	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408025	25906046	LVM	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408025	25906046	LVM	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408025	25906046	SCB	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408025	25906046	SCB	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408025	25906046	SDB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408025	25906046	SDB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408025	25906046	SDB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408025	25906046	SDB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408025	25906046	SEN	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408025	25906046	SEN	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408025	25906046	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408025	25906046	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408025	25906046	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408025	25906046	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408025	25906046	UT	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408025	25906046	UT	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408025	25906046	VM	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408025	25906046	VM	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408025	25906046	YRY	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4408025	25906046	YY	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
538280	15569391	EL	2	participated in maintenance of the cell lines and in vitro transcription analysis	participated in maintenance of the cell lines and in vitro transcription analysis	Performed the experiments	Investigation	YES
538280	15569391	HM	2	obtained the sequence of cirk1 genomic dna and did all the database searches to identify motifs and control regions in the 5-flanking region of cirk1|also conducted 5race, northern blot, cell culture, construction of deletion mutant, in vitro transcription analysis, and drafted the manuscript	obtained the sequence of cirk1 genomic dna and did all the database searches to identify motifs and control regions in the 5-flanking region of cirk1	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
538280	15569391	HM	2	obtained the sequence of cirk1 genomic dna and did all the database searches to identify motifs and control regions in the 5-flanking region of cirk1|also conducted 5race, northern blot, cell culture, construction of deletion mutant, in vitro transcription analysis, and drafted the manuscript	also conducted 5race, northern blot, cell culture, construction of deletion mutant, in vitro transcription analysis, and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
538280	15569391	JCO	2	participated in design and coordination of the study and finalized the manuscript	participated in design and coordination of the study and finalized the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Review & Editing	YES
538280	15569391	LCK	2	mapped much of the genomic structure and determined some of the sequence	mapped much of the genomic structure and determined some of the sequence	Performed the experiments	Investigation	YES
538280	15569391	NK	2	participated in maintenance of the cell lines and in vitro transcription analysis	participated in maintenance of the cell lines and in vitro transcription analysis	Performed the experiments	Investigation	YES
5824696	29503847	All authors	2	participated in writing the manuscript	participated in writing the manuscript	Wrote the paper	Writing - Original Draft	YES
4231366	24165577	JA	2	originated the article, did the research and wrote a first rough draft of the manuscript together|carried out the research on ethical and policy aspects|all read the first version and contributed editorial and critical suggestions|made revisions to the earlier draft and worked toward the final draft|have both read and approved the final version of the manuscript	originated the article, did the research and wrote a first rough draft of the manuscript together	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4231366	24165577	JA	2	originated the article, did the research and wrote a first rough draft of the manuscript together|carried out the research on ethical and policy aspects|all read the first version and contributed editorial and critical suggestions|made revisions to the earlier draft and worked toward the final draft|have both read and approved the final version of the manuscript	carried out the research on ethical and policy aspects	Performed the experiments	Investigation	YES
4231366	24165577	JA	2	originated the article, did the research and wrote a first rough draft of the manuscript together|carried out the research on ethical and policy aspects|all read the first version and contributed editorial and critical suggestions|made revisions to the earlier draft and worked toward the final draft|have both read and approved the final version of the manuscript	all read the first version and contributed editorial and critical suggestions	-	-	NO
4231366	24165577	JA	2	originated the article, did the research and wrote a first rough draft of the manuscript together|carried out the research on ethical and policy aspects|all read the first version and contributed editorial and critical suggestions|made revisions to the earlier draft and worked toward the final draft|have both read and approved the final version of the manuscript	made revisions to the earlier draft and worked toward the final draft	Performed the experiments|Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4231366	24165577	JA	2	originated the article, did the research and wrote a first rough draft of the manuscript together|carried out the research on ethical and policy aspects|all read the first version and contributed editorial and critical suggestions|made revisions to the earlier draft and worked toward the final draft|have both read and approved the final version of the manuscript	have both read and approved the final version of the manuscript	-	-	NO
4231366	24165577	TJ	2	originated the article, did the research and wrote a first rough draft of the manuscript together|all read the first version and contributed editorial and critical suggestions	originated the article, did the research and wrote a first rough draft of the manuscript together	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4231366	24165577	TJ	2	originated the article, did the research and wrote a first rough draft of the manuscript together|all read the first version and contributed editorial and critical suggestions	all read the first version and contributed editorial and critical suggestions	-	-	NO
5577696	28770595	AB	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5577696	28770595	AG	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5577696	28770595	AU	2	were responsible for the data collection	were responsible for the data collection	Performed the experiments	Investigation	YES
5577696	28770595	B. All	2	authors commented on drafts of the manuscript and approved the final version	authors commented on drafts of the manuscript and approved the final version	Wrote the paper	Writing - Original Draft	YES
5577696	28770595	LW	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5577696	28770595	PM	2	were responsible for the data collection	were responsible for the data collection	Performed the experiments	Investigation	YES
5577696	28770595	PT	2	were responsible for the data collection	were responsible for the data collection	Performed the experiments	Investigation	YES
5594225	28936220	HZ	2	assisted with the data analysis	assisted with the data analysis	Analyzed the data	Formal analysis	YES
5594225	28936220	JC	2	prepared cdna samples for sequencing	prepared cdna samples for sequencing	Performed the experiments	Investigation	YES
5594225	28936220	JL	2	provided helpful comments on the manuscript	provided helpful comments on the manuscript	-	-	NO
5594225	28936220	SL	2	prepared cdna samples for sequencing	prepared cdna samples for sequencing	Performed the experiments	Investigation	YES
5594225	28936220	SN	2	provided helpful comments on the manuscript	provided helpful comments on the manuscript	-	-	NO
5594225	28936220	XF	2	prepared cdna samples for sequencing	prepared cdna samples for sequencing	Performed the experiments	Investigation	YES
5594225	28936220	XZ	2	was responsible for the data analysis and drafted the manuscript	was responsible for the data analysis and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5594225	28936220	YW	2	provided guidance on the whole study and contributed with valuable discussions	provided guidance on the whole study and contributed with valuable discussions	-	Supervision	YES
5594225	28936220	YZ	2	prepared cdna samples for sequencing|assisted with the data analysis	prepared cdna samples for sequencing	Performed the experiments	Investigation	YES
5594225	28936220	YZ	2	prepared cdna samples for sequencing|assisted with the data analysis	assisted with the data analysis	Analyzed the data	Formal analysis	YES
4408027	25906320	IJW	PLoS5	Conceived and designed the experiments|Wrote the paper|Analysed and interpreted the results	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408027	25906320	IJW	PLoS5	Conceived and designed the experiments|Wrote the paper|Analysed and interpreted the results	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408027	25906320	IJW	PLoS5	Conceived and designed the experiments|Wrote the paper|Analysed and interpreted the results	Analysed and interpreted the results	Analyzed the data	Formal analysis	YES
4408027	25906320	KZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Analysed and interpreted the results	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408027	25906320	KZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Analysed and interpreted the results	Performed the experiments	Performed the experiments	Investigation	YES
4408027	25906320	KZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Analysed and interpreted the results	Analyzed the data	Analyzed the data	Formal analysis	YES
4408027	25906320	KZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Analysed and interpreted the results	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408027	25906320	KZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Analysed and interpreted the results	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408027	25906320	KZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Analysed and interpreted the results	Analysed and interpreted the results	Analyzed the data	Formal analysis	YES
4408027	25906320	MW	PLoS5	Conceived and designed the experiments|Wrote the paper|Analysed and interpreted the results	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408027	25906320	MW	PLoS5	Conceived and designed the experiments|Wrote the paper|Analysed and interpreted the results	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408027	25906320	MW	PLoS5	Conceived and designed the experiments|Wrote the paper|Analysed and interpreted the results	Analysed and interpreted the results	Analyzed the data	Formal analysis	YES
538281	15579207	AJB	2	contributed genotyping information and validated a number of snps	contributed genotyping information and validated a number of snps	Performed the experiments	Investigation|Validation	YES
538281	15579207	CW	2	provided running costs and assistance with writing the manuscript	provided running costs and assistance with writing the manuscript	Wrote the paper	Writing - Original Draft	YES
538281	15579207	SM-T	2	did all the coding, analysis, manuscript preparation and reviewer correspondence	did all the coding, analysis, manuscript preparation and reviewer correspondence	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5632479	29085677	Abigail Addison	2	contributed to the study design|drafted and revised the manuscript critically for important intellectual content and gave final approval	contributed to the study design	Conceived and designed the experiments	Methodology	YES
5632479	29085677	Abigail Addison	2	contributed to the study design|drafted and revised the manuscript critically for important intellectual content and gave final approval	drafted and revised the manuscript critically for important intellectual content and gave final approval	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5632479	29085677	Bismark Sarfo	2	conceived the research idea, designed the study, and analyzed the data|drafted and revised the manuscript critically for important intellectual content and gave final approval	conceived the research idea, designed the study, and analyzed the data	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
5632479	29085677	Bismark Sarfo	2	conceived the research idea, designed the study, and analyzed the data|drafted and revised the manuscript critically for important intellectual content and gave final approval	drafted and revised the manuscript critically for important intellectual content and gave final approval	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5632479	29085677	Naa Ashiley Vanderpuye	2	contributed to the study design|drafted and revised the manuscript critically for important intellectual content and gave final approval	contributed to the study design	Conceived and designed the experiments	Methodology	YES
5632479	29085677	Naa Ashiley Vanderpuye	2	contributed to the study design|drafted and revised the manuscript critically for important intellectual content and gave final approval	drafted and revised the manuscript critically for important intellectual content and gave final approval	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5632479	29085677	Peter Nyasulu	2	contributed to the study design|drafted and revised the manuscript critically for important intellectual content and gave final approval	contributed to the study design	Conceived and designed the experiments	Methodology	YES
5632479	29085677	Peter Nyasulu	2	contributed to the study design|drafted and revised the manuscript critically for important intellectual content and gave final approval	drafted and revised the manuscript critically for important intellectual content and gave final approval	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4408029	25905642	FW	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408029	25905642	JW	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408029	25905642	JYS	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408029	25905642	MYH	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408029	25905642	SF	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408029	25905642	SF	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408029	25905642	SF	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408029	25905642	WJC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408029	25905642	YBL	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408029	25905642	YL	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408029	25905642	YL	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408029	25905642	ZCZ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5594977	28936216	AA	2	performed the genotyping experiment	performed the genotyping experiment	Performed the experiments	Investigation	YES
5594977	28936216	AT	2	suggested and helped the data collection and analyses	suggested and helped the data collection and analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5594977	28936216	HH	2	designed ssr markers and performed part of the marker analysis	designed ssr markers and performed part of the marker analysis	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5594977	28936216	HL	2	wrote the manuscript|discussed the results, organized and revised the manuscript|performed the genotyping experiment	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5594977	28936216	HL	2	wrote the manuscript|discussed the results, organized and revised the manuscript|performed the genotyping experiment	discussed the results, organized and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5594977	28936216	HL	2	wrote the manuscript|discussed the results, organized and revised the manuscript|performed the genotyping experiment	performed the genotyping experiment	Performed the experiments	Investigation	YES
5594977	28936216	HS	2	commented the manuscript and supported the experiment	commented the manuscript and supported the experiment	-	-	NO
5594977	28936216	HTo	2	suggested and helped the data collection and analyses	suggested and helped the data collection and analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5594977	28936216	HTs	2	suggested and helped the data collection and analyses	suggested and helped the data collection and analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5594977	28936216	KF	2	discussed the results, organized and revised the manuscript|organized the project	discussed the results, organized and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5594977	28936216	KF	2	discussed the results, organized and revised the manuscript|organized the project	organized the project	-	Project administration	YES
5594977	28936216	KH	2	discussed the results, organized and revised the manuscript	discussed the results, organized and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5594977	28936216	MY	2	supported and conducted some statistical analyses	supported and conducted some statistical analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5594977	28936216	NW	2	commented the manuscript and supported the experiment	commented the manuscript and supported the experiment	-	-	NO
5594977	28936216	PS	2	collected and provided philippines accessions	collected and provided philippines accessions	Performed the experiments	Investigation	YES
5594977	28936216	SS	2	designed ssr markers and performed part of the marker analysis	designed ssr markers and performed part of the marker analysis	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5594977	28936216	ST	2	discussed the results, organized and revised the manuscript	discussed the results, organized and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5594977	28936216	TA	2	suggested and helped the data collection and analyses	suggested and helped the data collection and analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5594977	28936216	TS	2	performed the genotyping experiment	performed the genotyping experiment	Performed the experiments	Investigation	YES
5824697	29503846	AT	2	also reviewed the manuscript	also reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5824697	29503846	CM	2	was responsible for the performance of the in vitro and in vivo studies and revised the manuscript	was responsible for the performance of the in vitro and in vivo studies and revised the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5824697	29503846	RS	2	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5824697	29503846	SH	2	performed the in vivo studies	performed the in vivo studies	Performed the experiments	Investigation	YES
5383948	28388875	CRQ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5383948	28388875	JLK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5383948	28388875	JLK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
5383948	28388875	JLK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5383948	28388875	KMC	PLoS5	Performed the experiments|Analyzed the data|Wrote the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
5383948	28388875	KMC	PLoS5	Performed the experiments|Analyzed the data|Wrote the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
5383948	28388875	KMC	PLoS5	Performed the experiments|Analyzed the data|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5383948	28388875	KT	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5383948	28388875	LAR	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5383948	28388875	LAR	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4304039	25381041	JLV	2	have made substantial contributions in drafting the manuscript and revising it critically for important intellectual content, that they have given final approval of the version to be published, and that they have participated sufficiently in the work to take public responsibility for appropriate portions of the content|have read and approved the final manuscript	have made substantial contributions in drafting the manuscript and revising it critically for important intellectual content, that they have given final approval of the version to be published, and that they have participated sufficiently in the work to take public responsibility for appropriate portions of the content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4304039	25381041	JLV	2	have made substantial contributions in drafting the manuscript and revising it critically for important intellectual content, that they have given final approval of the version to be published, and that they have participated sufficiently in the work to take public responsibility for appropriate portions of the content|have read and approved the final manuscript	have read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4304039	25381041	MYR	2	have made substantial contributions in drafting the manuscript and revising it critically for important intellectual content, that they have given final approval of the version to be published, and that they have participated sufficiently in the work to take public responsibility for appropriate portions of the content|have read and approved the final manuscript	have made substantial contributions in drafting the manuscript and revising it critically for important intellectual content, that they have given final approval of the version to be published, and that they have participated sufficiently in the work to take public responsibility for appropriate portions of the content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4304039	25381041	MYR	2	have made substantial contributions in drafting the manuscript and revising it critically for important intellectual content, that they have given final approval of the version to be published, and that they have participated sufficiently in the work to take public responsibility for appropriate portions of the content|have read and approved the final manuscript	have read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4304047	25366256	JCT	2	conceived of the study, assisted with survey development, and helped to draft the manuscript	conceived of the study, assisted with survey development, and helped to draft the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
4304047	25366256	KMH	2	assisted with survey development, performed the statistical analyses, and helped to draft the manuscript	assisted with survey development, performed the statistical analyses, and helped to draft the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4304047	25366256	RMA	2	conceived of the study, assisted with survey development, and drafted the manuscript	conceived of the study, assisted with survey development, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
5596062	28943880	JAE	2	wrote the review and thank all the authors who contributed with data for all krp manuscripts mentioned herein	wrote the review and thank all the authors who contributed with data for all krp manuscripts mentioned herein	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Original Draft|Writing - Review & Editing	YES
5596062	28943880	PV	2	wrote the review and thank all the authors who contributed with data for all krp manuscripts mentioned herein	wrote the review and thank all the authors who contributed with data for all krp manuscripts mentioned herein	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Original Draft|Writing - Review & Editing	YES
5824698	29503853	All authors	2	contributed with documented data on their own national situation|also read and approved the final manuscript	contributed with documented data on their own national situation	Contributed reagents/materials/analysis tools	Resources	YES
5824698	29503853	All authors	2	contributed with documented data on their own national situation|also read and approved the final manuscript	also read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4408030	25906372	CCW	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4408030	25906372	JCL	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408030	25906372	JCL	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408030	25906372	JCL	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408030	25906372	JCL	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408030	25906372	RSJ	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4408030	25906372	SAL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408030	25906372	SAL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408030	25906372	SAL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408030	25906372	WYW	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4408030	25906372	WYW	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4304063	25381149	DM	7	Data collection and principle author	Data collection and principle author	Performed the experiments	Investigation	YES
4304063	25381149	EF	7	Data Collection	Data Collection	Performed the experiments	Investigation	YES
4304063	25381149	IP	7	Data Collection	Data Collection	Performed the experiments	Investigation	YES
4304063	25381149	MM	7	Data Collection	Data Collection	Performed the experiments	Investigation	YES
4304063	25381149	NS	7	Data Collection	Data Collection	Performed the experiments	Investigation	YES
4304063	25381149	PL	7	Data collection	Data collection	Performed the experiments	Investigation	YES
4304063	25381149	RM	7	Analysis of data	Analysis of data	Analyzed the data	Formal analysis	YES
4304063	25381149	SP	7	Data Collection	Data Collection	Performed the experiments	Investigation	YES
4304063	25381149	TH	7	Method	Method	Performed the experiments	-	YES
5383966	28388876	AB	2	made the pppgpp measurements	made the pppgpp measurements	Performed the experiments	Investigation	YES
5383966	28388876	AG	2	sequenced, assembled and annotated the a522 genome	sequenced, assembled and annotated the a522 genome	Performed the experiments	Investigation	YES
5383966	28388876	AS	2	sequenced, assembled and annotated the a522 genome	sequenced, assembled and annotated the a522 genome	Performed the experiments	Investigation	YES
5383966	28388876	BJA	2	conducted the microarray	conducted the microarray	Performed the experiments	Investigation	YES
5383966	28388876	CL	2	performed the elementary and flux balance analyses	performed the elementary and flux balance analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5383966	28388876	CS	2	designed the study, analysed the data and wrote the paper	designed the study, analysed the data and wrote the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5383966	28388876	EK	2	made the pppgpp measurements	made the pppgpp measurements	Performed the experiments	Investigation	YES
5383966	28388876	JB	2	sequenced, assembled and annotated the a522 genome	sequenced, assembled and annotated the a522 genome	Performed the experiments	Investigation	YES
5383966	28388876	LK	2	conducted the microarray	conducted the microarray	Performed the experiments	Investigation	YES
5383966	28388876	MD	2	performed the ppi network analyses	performed the ppi network analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5383966	28388876	PCR	2	growth experiments and constructed all mutant strains of this work	growth experiments and constructed all mutant strains of this work	Performed the experiments	Investigation	YES
5383966	28388876	TD	2	performed the elementary and flux balance analyses	performed the elementary and flux balance analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5383966	28388876	TM	2	performed the ppi network analyses	performed the ppi network analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4408031	25906364	AA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408031	25906364	AA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408031	25906364	AA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408031	25906364	LJK	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408031	25906364	LJK	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408031	25906364	MT	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408031	25906364	MT	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408031	25906364	MT	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408031	25906364	MT	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408031	25906364	PB	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408031	25906364	PB	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408031	25906364	SA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408031	25906364	SA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408031	25906364	SA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408031	25906364	SA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408031	25906364	SA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5824699	29503849	PKP	2	were involved in drafting the manuscript	were involved in drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
5824699	29503849	ST	2	were involved in drafting the manuscript	were involved in drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
5671668	29201460	All authors	2	designed the data collection tool and wrote and approved the final manuscript	designed the data collection tool and wrote and approved the final manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5671668	29201460	John Bosco Alege	2	provided technical research guidance	provided technical research guidance	-	Supervision	YES
5671668	29201460	Jonathan Izudi	2	performed the data analysis and wrote the draft and final manuscripts|is the first author	performed the data analysis and wrote the draft and final manuscripts	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5671668	29201460	Jonathan Izudi	2	performed the data analysis and wrote the draft and final manuscripts|is the first author	is the first author	-	-	NO
5671668	29201460	Sylvia Auma	2	conceptualized and designed the study	conceptualized and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5596067	28943881	AA	PLoS52	analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5596067	28943881	BZ	PLoS52	designed the research|analyzed the data and wrote the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
5596067	28943881	BZ	PLoS52	designed the research|analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5596067	28943881	CX	PLoS52	designed the research|analyzed the data and wrote the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
5596067	28943881	CX	PLoS52	designed the research|analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5596067	28943881	KC	PLoS52	analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5596067	28943881	KL-W	PLoS52	analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5596067	28943881	KW	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5596067	28943881	WD	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5596067	28943881	YZ	PLoS52	designed the research|performed the experiments|analyzed the data and wrote the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
5596067	28943881	YZ	PLoS52	designed the research|performed the experiments|analyzed the data and wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5596067	28943881	YZ	PLoS52	designed the research|performed the experiments|analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4529913	26273642	Aimee Grant	2	conceptualised the project and developed the study protocol	conceptualised the project and developed the study protocol	Conceived and designed the experiments	Conceptualization|Methodology	YES
4529913	26273642	Ali Bakir	2	commented on the study protocol|in qualitative methods|conducted all focus group discussions and transcribed audio-recordings	commented on the study protocol	Conceived and designed the experiments	Methodology	YES
4529913	26273642	Ali Bakir	2	commented on the study protocol|in qualitative methods|conducted all focus group discussions and transcribed audio-recordings	in qualitative methods	Performed the experiments	-	YES
4529913	26273642	Ali Bakir	2	commented on the study protocol|in qualitative methods|conducted all focus group discussions and transcribed audio-recordings	conducted all focus group discussions and transcribed audio-recordings	Performed the experiments	Investigation	YES
4529913	26273642	Mohammed Ali	2	commented on the study protocol|in qualitative methods|conducted all focus group discussions and transcribed audio-recordings	commented on the study protocol	Conceived and designed the experiments	Methodology	YES
4529913	26273642	Mohammed Ali	2	commented on the study protocol|in qualitative methods|conducted all focus group discussions and transcribed audio-recordings	in qualitative methods	Performed the experiments	-	YES
4529913	26273642	Mohammed Ali	2	commented on the study protocol|in qualitative methods|conducted all focus group discussions and transcribed audio-recordings	conducted all focus group discussions and transcribed audio-recordings	Performed the experiments	Investigation	YES
4529913	26273642	Mohammed Jawad	2	conceptualised the project and developed the study protocol|wrote the first draft of the paper	conceptualised the project and developed the study protocol	Conceived and designed the experiments	Conceptualization|Methodology	YES
4529913	26273642	Mohammed Jawad	2	conceptualised the project and developed the study protocol|wrote the first draft of the paper	wrote the first draft of the paper	Wrote the paper	Writing - Original Draft	YES
5824700	29503850	AJR	2	contributed to the writing of the manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5824700	29503850	ATK	2	contributed to the writing of the manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5824700	29503850	ATU	2	contributed to the writing of the manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5824700	29503850	All the authors	2	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5824700	29503850	BHF	2	led the writing of the manuscript	led the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5824700	29503850	BZ	2	led the writing of the manuscript	led the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5824700	29503850	GP	2	led the conceptualization of the work|led the writing of the manuscript	led the conceptualization of the work	Conceived and designed the experiments	Conceptualization	YES
5824700	29503850	GP	2	led the conceptualization of the work|led the writing of the manuscript	led the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5824700	29503850	LM	2	led the writing of the manuscript	led the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
4408032	25906075	CA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the software used in the analysis|Interpreted the findings of the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408032	25906075	CA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the software used in the analysis|Interpreted the findings of the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4408032	25906075	CA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the software used in the analysis|Interpreted the findings of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4408032	25906075	CA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the software used in the analysis|Interpreted the findings of the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408032	25906075	CA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the software used in the analysis|Interpreted the findings of the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408032	25906075	CA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the software used in the analysis|Interpreted the findings of the manuscript	Designed the software used in the analysis	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
4408032	25906075	CA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the software used in the analysis|Interpreted the findings of the manuscript	Interpreted the findings of the manuscript	Analyzed the data	Formal analysis	YES
4408032	25906075	MLU	PLoS5	Analyzed the data|Wrote the paper|Interpreted the findings of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4408032	25906075	MLU	PLoS5	Analyzed the data|Wrote the paper|Interpreted the findings of the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408032	25906075	MLU	PLoS5	Analyzed the data|Wrote the paper|Interpreted the findings of the manuscript	Interpreted the findings of the manuscript	Analyzed the data	Formal analysis	YES
5383967	28388877	KA	2	designed experiments and drafted the manuscript	designed experiments and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5383967	28388877	KN	2	designed experiments and drafted the manuscript	designed experiments and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5383967	28388877	MU	2	conceived the project, designed and performed experiments, conducted bioinformatic analysis and drafted the manuscript	conceived the project, designed and performed experiments, conducted bioinformatic analysis and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5383967	28388877	TI	2	conceived the project, designed experiments, conducted bioinformatic analysis, coordinated the study and drafted the manuscript	conceived the project, designed experiments, conducted bioinformatic analysis, coordinated the study and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Project administration|Writing - Original Draft	YES
5383967	28388877	TO	2	contributed to the sample preparation for directional rna seq	contributed to the sample preparation for directional rna seq	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5596797	28943882	C-JJ	2	designed the study|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5596797	28943882	C-JJ	2	designed the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5596797	28943882	HZ	2	designed the study|performed the data collection, statistical analysis, and figure mapping|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5596797	28943882	HZ	2	designed the study|performed the data collection, statistical analysis, and figure mapping|wrote the manuscript	performed the data collection, statistical analysis, and figure mapping	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
5596797	28943882	HZ	2	designed the study|performed the data collection, statistical analysis, and figure mapping|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5596797	28943882	M-MW	2	performed the laboratory experiments	performed the laboratory experiments	Performed the experiments	Investigation	YES
5596797	28943882	X-LL	2	performed the data collection, statistical analysis, and figure mapping	performed the data collection, statistical analysis, and figure mapping	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
5596797	28943882	YYa	2	performed the laboratory experiments	performed the laboratory experiments	Performed the experiments	Investigation	YES
5596797	28943882	Z-WL	2	designed the study|provided scientific expertise	designed the study	Conceived and designed the experiments	Methodology	YES
5596797	28943882	Z-WL	2	designed the study|provided scientific expertise	provided scientific expertise	-	-	NO
5577702	28530042	AJ	2	designed the study|wrote the first draft of the paper	designed the study	Conceived and designed the experiments	Methodology	YES
5577702	28530042	AJ	2	designed the study|wrote the first draft of the paper	wrote the first draft of the paper	Wrote the paper	Writing - Original Draft	YES
5577702	28530042	All authors	2	commented on the paper and approved the final version	commented on the paper and approved the final version	-	-	NO
5577702	28530042	CS	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5577702	28530042	DMG	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5577702	28530042	HA	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5577702	28530042	JC	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5577702	28530042	SJ	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5577702	28530042	TH	2	undertook the data linkage	undertook the data linkage	Performed the experiments	Investigation	YES
4408033	25906186	A. Beauchet	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408033	25906186	A. Beauchet	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408033	25906186	A. Beauchet	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408033	25906186	A. Beauchet	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408033	25906186	A. Beauchet	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408033	25906186	A. Bourez	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408033	25906186	A. Bourez	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4408033	25906186	A. Bourez	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4408033	25906186	A. Bourez	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408033	25906186	CK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408033	25906186	CK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408033	25906186	CK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408033	25906186	CK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408033	25906186	CK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408033	25906186	FDR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408033	25906186	FDR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4408033	25906186	FDR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4408033	25906186	FDR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408033	25906186	NM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408033	25906186	NM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408033	25906186	NM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408033	25906186	NM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408033	25906186	NM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408033	25906186	OD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408033	25906186	OD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408033	25906186	OD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408033	25906186	OD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408033	25906186	OD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408033	25906186	SC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4408033	25906186	SC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5676343	29209538	Charles Peter Osingada	2	were responsible for the study conception and design|were responsible for the data collection and analysis|were responsible for data interpretation and drafting of the manuscript|made critical revisions to the paper for important intellectual content	were responsible for the study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5676343	29209538	Charles Peter Osingada	2	were responsible for the study conception and design|were responsible for the data collection and analysis|were responsible for data interpretation and drafting of the manuscript|made critical revisions to the paper for important intellectual content	were responsible for the data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5676343	29209538	Charles Peter Osingada	2	were responsible for the study conception and design|were responsible for the data collection and analysis|were responsible for data interpretation and drafting of the manuscript|made critical revisions to the paper for important intellectual content	were responsible for data interpretation and drafting of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5676343	29209538	Charles Peter Osingada	2	were responsible for the study conception and design|were responsible for the data collection and analysis|were responsible for data interpretation and drafting of the manuscript|made critical revisions to the paper for important intellectual content	made critical revisions to the paper for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5676343	29209538	Damalie Nakanjako	2	were responsible for the study conception and design|made critical revisions to the paper for important intellectual content	were responsible for the study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5676343	29209538	Damalie Nakanjako	2	were responsible for the study conception and design|made critical revisions to the paper for important intellectual content	made critical revisions to the paper for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5676343	29209538	Monica Okuga	2	were responsible for the study conception and design|were responsible for the data collection and analysis|were responsible for data interpretation and drafting of the manuscript|made critical revisions to the paper for important intellectual content	were responsible for the study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5676343	29209538	Monica Okuga	2	were responsible for the study conception and design|were responsible for the data collection and analysis|were responsible for data interpretation and drafting of the manuscript|made critical revisions to the paper for important intellectual content	were responsible for the data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5676343	29209538	Monica Okuga	2	were responsible for the study conception and design|were responsible for the data collection and analysis|were responsible for data interpretation and drafting of the manuscript|made critical revisions to the paper for important intellectual content	were responsible for data interpretation and drafting of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5676343	29209538	Monica Okuga	2	were responsible for the study conception and design|were responsible for the data collection and analysis|were responsible for data interpretation and drafting of the manuscript|made critical revisions to the paper for important intellectual content	made critical revisions to the paper for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5676343	29209538	Nelson Kaulukusi Sewankambo	2	were responsible for the study conception and design|made critical revisions to the paper for important intellectual content	were responsible for the study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5676343	29209538	Nelson Kaulukusi Sewankambo	2	were responsible for the study conception and design|made critical revisions to the paper for important intellectual content	made critical revisions to the paper for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5676343	29209538	Rose Chalo Nabirye	2	were responsible for the study conception and design|made critical revisions to the paper for important intellectual content	were responsible for the study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5676343	29209538	Rose Chalo Nabirye	2	were responsible for the study conception and design|made critical revisions to the paper for important intellectual content	made critical revisions to the paper for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5824701	29503851	ES	2	designed the study and edited the manuscript	designed the study and edited the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5824701	29503851	HE	2	helped with the interpretation of the results and critically revised the manuscript	helped with the interpretation of the results and critically revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5824701	29503851	IK	2	performed radiosynthesis studies	performed radiosynthesis studies	Performed the experiments	Investigation	YES
5824701	29503851	PB	2	helped with the design of the radiosynthetic protocols and drafted the manuscript	helped with the design of the radiosynthetic protocols and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5824701	29503851	WP	2	designed the study and drafted the manuscript	designed the study and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
1762303	17183633	AF	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762303	17183633	CB	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762303	17183633	CB	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762303	17183633	EA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762303	17183633	EA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762303	17183633	EA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762303	17183633	JH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762303	17183633	JH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762303	17183633	JH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762303	17183633	JH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762303	17183633	MD	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762303	17183633	MD	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5599772	28951735	AP	2	contributed equally to this manuscript|planned and designed the experiments|processed the images	contributed equally to this manuscript	-	-	NO
5599772	28951735	AP	2	contributed equally to this manuscript|planned and designed the experiments|processed the images	planned and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5599772	28951735	AP	2	contributed equally to this manuscript|planned and designed the experiments|processed the images	processed the images	Analyzed the data	Visualization	YES
5599772	28951735	BG	2	contributed equally to this manuscript|planned and designed the experiments	contributed equally to this manuscript	-	-	NO
5599772	28951735	BG	2	contributed equally to this manuscript|planned and designed the experiments	planned and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5599772	28951735	C. All	2	authors have read and approved the final manuscript	authors have read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5599772	28951735	DJ	2	obtained funding for the study|planned and designed the experiments	obtained funding for the study	-	Funding acquisition	YES
5599772	28951735	DJ	2	obtained funding for the study|planned and designed the experiments	planned and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5599772	28951735	GH	2	obtained funding for the study|planned and designed the experiments	obtained funding for the study	-	Funding acquisition	YES
5599772	28951735	GH	2	obtained funding for the study|planned and designed the experiments	planned and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5599772	28951735	JWa	2	processed the images	processed the images	Analyzed the data	Visualization	YES
5599772	28951735	JWi	2	collected the on-ground and aerial data, respectively	collected the on-ground and aerial data, respectively	Performed the experiments	Investigation	YES
5599772	28951735	KL	2	collected the on-ground and aerial data, respectively|processed the images	collected the on-ground and aerial data, respectively	Performed the experiments	Investigation	YES
5599772	28951735	KL	2	collected the on-ground and aerial data, respectively|processed the images	processed the images	Analyzed the data	Visualization	YES
5599772	28951735	LS	2	processed the images	processed the images	Analyzed the data	Visualization	YES
5599772	28951735	ME	2	collected the on-ground and aerial data, respectively	collected the on-ground and aerial data, respectively	Performed the experiments	Investigation	YES
5599772	28951735	SC	2	planned and designed the experiments	planned and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408034	25906352	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408034	25906352	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408034	25906352	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408034	25906352	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408034	25906352	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408034	25906352	RD	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4408034	25906352	RG	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4408034	25906352	RG	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762304	17183712	DF	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762304	17183712	DF	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762304	17183712	MK	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762304	17183712	MK	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762304	17183712	MK	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5383985	28388878	AM	2	conceived the study, undertook the glasshouse trails, and prepared the manuscript|oversaw the collection and analysis of the gas exchange data|undertook the validation study	conceived the study, undertook the glasshouse trails, and prepared the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
5383985	28388878	AM	2	conceived the study, undertook the glasshouse trails, and prepared the manuscript|oversaw the collection and analysis of the gas exchange data|undertook the validation study	oversaw the collection and analysis of the gas exchange data	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Supervision	YES
5383985	28388878	AM	2	conceived the study, undertook the glasshouse trails, and prepared the manuscript|oversaw the collection and analysis of the gas exchange data|undertook the validation study	undertook the validation study	Performed the experiments	Investigation|Validation	YES
5383985	28388878	AS	2	conceived the study, undertook the glasshouse trails, and prepared the manuscript	conceived the study, undertook the glasshouse trails, and prepared the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
5383985	28388878	CM	2	undertook the validation study	undertook the validation study	Performed the experiments	Investigation|Validation	YES
5383985	28388878	JT	2	undertook the sequence alignment, annotation, analysis of the sequence data, creation of pathway network and some manuscript preparation	undertook the sequence alignment, annotation, analysis of the sequence data, creation of pathway network and some manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Formal analysis|Investigation|Writing - Original Draft	YES
5383985	28388878	MN	2	undertook the sequence alignment, annotation, analysis of the sequence data, creation of pathway network and some manuscript preparation	undertook the sequence alignment, annotation, analysis of the sequence data, creation of pathway network and some manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Formal analysis|Investigation|Writing - Original Draft	YES
5383985	28388878	PR	2	undertook the sequence alignment, annotation, analysis of the sequence data, creation of pathway network and some manuscript preparation	undertook the sequence alignment, annotation, analysis of the sequence data, creation of pathway network and some manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Formal analysis|Investigation|Writing - Original Draft	YES
5383985	28388878	SEQ	2	library preparation and sequencing	library preparation and sequencing	Performed the experiments	Investigation	YES
5577703	28530041	All authors	2	contributed to and approved the final draft	contributed to and approved the final draft	Wrote the paper	Writing - Original Draft	YES
5599775	28951734	HW	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5599775	28951734	LZ	PLoS52	monitored the experimental work	monitored the experimental work	Performed the experiments	Investigation|Supervision	YES
5599775	28951734	XL	PLoS52	conceived and designed the experiments|monitored the experimental work|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5599775	28951734	XL	PLoS52	conceived and designed the experiments|monitored the experimental work|wrote the paper	monitored the experimental work	Performed the experiments	Investigation|Supervision	YES
5599775	28951734	XL	PLoS52	conceived and designed the experiments|monitored the experimental work|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5599775	28951734	XY	PLoS52	conceived and designed the experiments|performed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5599775	28951734	XY	PLoS52	conceived and designed the experiments|performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5599775	28951734	YF	PLoS52	contributed materials of transgenic rice	contributed materials of transgenic rice	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5599775	28951734	ZZ	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5599775	28951734	ZZ	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5599775	28951734	ZZ	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5599775	28951734	ZZ	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4529917	26273643	Meng-Tao Li	2	contributed equally to this work	contributed equally to this work	-	-	NO
4529917	26273643	Shuang Zhou	2	contributed equally to this work	contributed equally to this work	-	-	NO
4529917	26273643	Yu-Yan Jia	2	contributed equally to this work	contributed equally to this work	-	-	NO
5824703	29503854	CZ	2	conducted the experiments|summarized and interpreted the data	conducted the experiments	Performed the experiments	Investigation	YES
5824703	29503854	CZ	2	conducted the experiments|summarized and interpreted the data	summarized and interpreted the data	Analyzed the data	Formal analysis	YES
5824703	29503854	DW	2	conceived and designed the complete study	conceived and designed the complete study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5824703	29503854	FB	2	conceived and designed the complete study	conceived and designed the complete study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5824703	29503854	JGG	2	conducted the experiments	conducted the experiments	Performed the experiments	Investigation	YES
5824703	29503854	KF	2	conducted the experiments	conducted the experiments	Performed the experiments	Investigation	YES
5824703	29503854	KSL	2	conceived and designed the complete study|summarized and interpreted the data	conceived and designed the complete study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5824703	29503854	KSL	2	conceived and designed the complete study|summarized and interpreted the data	summarized and interpreted the data	Analyzed the data	Formal analysis	YES
5824703	29503854	LL	2	conducted the experiments|summarized and interpreted the data	conducted the experiments	Performed the experiments	Investigation	YES
5824703	29503854	LL	2	conducted the experiments|summarized and interpreted the data	summarized and interpreted the data	Analyzed the data	Formal analysis	YES
5824703	29503854	MW	2	conceived and designed the complete study|conducted the experiments|summarized and interpreted the data	conceived and designed the complete study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5824703	29503854	MW	2	conceived and designed the complete study|conducted the experiments|summarized and interpreted the data	conducted the experiments	Performed the experiments	Investigation	YES
5824703	29503854	MW	2	conceived and designed the complete study|conducted the experiments|summarized and interpreted the data	summarized and interpreted the data	Analyzed the data	Formal analysis	YES
5824703	29503854	WE	2	conducted the experiments	conducted the experiments	Performed the experiments	Investigation	YES
5824703	29503854	ZZ	2	conducted the experiments|summarized and interpreted the data	conducted the experiments	Performed the experiments	Investigation	YES
5824703	29503854	ZZ	2	conducted the experiments|summarized and interpreted the data	summarized and interpreted the data	Analyzed the data	Formal analysis	YES
4408035	25906265	ER	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408035	25906265	ER	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408035	25906265	ES	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408035	25906265	ES	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408035	25906265	ES	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408035	25906265	ES	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408035	25906265	ES	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408035	25906265	FG	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408035	25906265	FG	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408035	25906265	NB	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408035	25906265	NB	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408035	25906265	WF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408035	25906265	WF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408035	25906265	WF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408035	25906265	WF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408035	25906265	WF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408035	25906265	WS	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408035	25906265	WS	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762305	17183692	AR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762305	17183692	AR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762305	17183692	AR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762305	17183692	AR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762305	17183692	CW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762305	17183692	CW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762305	17183692	CW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762305	17183692	TZ	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762305	17183692	TZ	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5705869	29270318	A. Baguiya	2	conducted the manuscript review	conducted the manuscript review	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5705869	29270318	A. Grosso	2	contributed to study design, implementation, and manuscript writing	contributed to study design, implementation, and manuscript writing	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5705869	29270318	B. C. Samadoulougou	2	helped in study implementation, data cleaning, and manuscript review	helped in study implementation, data cleaning, and manuscript review	Performed the experiments|Wrote the paper	Data curation|Investigation|Writing - Review & Editing	YES
5705869	29270318	H. G. Ouedraogo	2	contributed to study design, implementation, and manuscript writing	contributed to study design, implementation, and manuscript writing	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5705869	29270318	M. Lougue	2	contributed to study design, implementation, and manuscript writing	contributed to study design, implementation, and manuscript writing	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5705869	29270318	N. Sawadogo	2	conducted the manuscript review	conducted the manuscript review	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5705869	29270318	Nicolas Barro	2	conducted the manuscript review	conducted the manuscript review	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5705869	29270318	O. Ky-Zerbo	2	contributed to study design, implementation, and manuscript writing	contributed to study design, implementation, and manuscript writing	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5705869	29270318	S. Baral	2	contributed to study design, implementation, and manuscript writing	contributed to study design, implementation, and manuscript writing	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5705869	29270318	S. Goodman	2	assisted in manuscript writing	assisted in manuscript writing	Wrote the paper	Writing - Original Draft	YES
5705869	29270318	S. Kouanda	2	contributed to study design, implementation, and manuscript writing	contributed to study design, implementation, and manuscript writing	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5705869	29270318	Y. Traore	2	conducted the manuscript review	conducted the manuscript review	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5600955	28955372	All authors	7	Ideal candidates for the astronauts functional salad|Challenges ahead	Ideal candidates for the astronauts functional salad	Conceived and designed the experiments	Conceptualization	YES
5600955	28955372	All authors	7	Ideal candidates for the astronauts functional salad|Challenges ahead	Challenges ahead	-	-	NO
5600955	28955372	MK	7	Had the original idea|Prolonged presence in space and the need for a functional diet|Space farm essentials and constraints	Had the original idea	Conceived and designed the experiments	Conceptualization	YES
5600955	28955372	MK	7	Had the original idea|Prolonged presence in space and the need for a functional diet|Space farm essentials and constraints	Prolonged presence in space and the need for a functional diet	-	-	NO
5600955	28955372	MK	7	Had the original idea|Prolonged presence in space and the need for a functional diet|Space farm essentials and constraints	Space farm essentials and constraints	Performed the experiments	Investigation	YES
5600955	28955372	SD	7	Space farm essentials and constraints	Space farm essentials and constraints	Performed the experiments	Investigation	YES
5600955	28955372	YR	7	Had the original idea|Prolonged presence in space and the need for a functional diet|Space farm essentials and constraints	Had the original idea	Conceived and designed the experiments	Conceptualization	YES
5600955	28955372	YR	7	Had the original idea|Prolonged presence in space and the need for a functional diet|Space farm essentials and constraints	Prolonged presence in space and the need for a functional diet	-	-	NO
5600955	28955372	YR	7	Had the original idea|Prolonged presence in space and the need for a functional diet|Space farm essentials and constraints	Space farm essentials and constraints	Performed the experiments	Investigation	YES
4529918	26273639	Fei Han	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
4529918	26273639	Jinxi He	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
1762306	17183726	AJ	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762306	17183726	AJ	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762306	17183726	AS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1762306	17183726	JD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762306	17183726	JD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762306	17183726	JD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762306	17183726	JD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762306	17183726	JZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762306	17183726	JZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762306	17183726	JZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762306	17183726	JZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762306	17183726	JZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5738585	29362673	Agnes Kiragga	2	conducted the analysis|copy edited the final version of the manuscript	conducted the analysis	Performed the experiments	Investigation	YES
5738585	29362673	Agnes Kiragga	2	conducted the analysis|copy edited the final version of the manuscript	copy edited the final version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5738585	29362673	Barbara Castelnuovo	2	conceived the study and wrote the first draft of the manuscript	conceived the study and wrote the first draft of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5738585	29362673	Frank Mubiru	2	conducted the analysis	conducted the analysis	Performed the experiments	Investigation	YES
5738585	29362673	Ivan Kalule	2	contributed in extracting interpreting the data	contributed in extracting interpreting the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5738585	29362673	Shadia Nakalema	2	contributed in extracting interpreting the data	contributed in extracting interpreting the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5738585	29362673	all authors	2	read the final version of the manuscript	read the final version of the manuscript	-	-	NO
4408036	25905720	AYK	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408036	25905720	AYK	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408036	25905720	AYK	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408036	25905720	JEL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408036	25905720	JEL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408036	25905720	JEL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3636492	23730366	Antonio Roman	2	was responsible for patient selection and clinical follow-up, and for drafting and revising the manuscript	was responsible for patient selection and clinical follow-up, and for drafting and revising the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3636492	23730366	BSc	2	was responsible for patient selection and clinical follow-up, and for drafting and revising the manuscript	was responsible for patient selection and clinical follow-up, and for drafting and revising the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3636492	23730366	Carlos Bravo	2	was responsible for patient selection and clinical follow-up, and for drafting and revising the manuscript	was responsible for patient selection and clinical follow-up, and for drafting and revising the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3636492	23730366	Christian Arredondo	2	was responsible for drafting and revising the manuscript	was responsible for drafting and revising the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3636492	23730366	Enric Domingo	2	was the principal investigator of the study and the corresponding author|was responsible for the design of the study, the performance of the cardiac catheterizations, the interpretation of data and the paper writing	was the principal investigator of the study and the corresponding author	Conceived and designed the experiments|Wrote the paper	Conceptualization|Funding acquisition|Writing - Original Draft	YES
3636492	23730366	Enric Domingo	2	was the principal investigator of the study and the corresponding author|was responsible for the design of the study, the performance of the cardiac catheterizations, the interpretation of data and the paper writing	was responsible for the design of the study, the performance of the cardiac catheterizations, the interpretation of data and the paper writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology	YES
3636492	23730366	IVUS	2	acquisition and measuring	acquisition and measuring	-	-	NO
3636492	23730366	MD	2	was the principal investigator of the study and the corresponding author|was responsible for the design of the study, the performance of the cardiac catheterizations, the interpretation of data and the paper writing|was responsible for data interpretation and manuscript revision|was responsible for histological analysis|was responsible for drafting and revising the manuscript|was responsible for patient selection and clinical follow-up|was responsible for patient selection and clinical follow-up, and for drafting and revising the manuscript|was responsible for patient selection and clinical follow-up, and for drafting and revising the manuscript	was the principal investigator of the study and the corresponding author	Conceived and designed the experiments|Wrote the paper	Conceptualization|Funding acquisition|Writing - Original Draft	YES
3636492	23730366	MD	2	was the principal investigator of the study and the corresponding author|was responsible for the design of the study, the performance of the cardiac catheterizations, the interpretation of data and the paper writing|was responsible for data interpretation and manuscript revision|was responsible for histological analysis|was responsible for drafting and revising the manuscript|was responsible for patient selection and clinical follow-up|was responsible for patient selection and clinical follow-up, and for drafting and revising the manuscript|was responsible for patient selection and clinical follow-up, and for drafting and revising the manuscript	was responsible for the design of the study, the performance of the cardiac catheterizations, the interpretation of data and the paper writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology	YES
3636492	23730366	MD	2	was the principal investigator of the study and the corresponding author|was responsible for the design of the study, the performance of the cardiac catheterizations, the interpretation of data and the paper writing|was responsible for data interpretation and manuscript revision|was responsible for histological analysis|was responsible for drafting and revising the manuscript|was responsible for patient selection and clinical follow-up|was responsible for patient selection and clinical follow-up, and for drafting and revising the manuscript|was responsible for patient selection and clinical follow-up, and for drafting and revising the manuscript	was responsible for data interpretation and manuscript revision	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
3636492	23730366	MD	2	was the principal investigator of the study and the corresponding author|was responsible for the design of the study, the performance of the cardiac catheterizations, the interpretation of data and the paper writing|was responsible for data interpretation and manuscript revision|was responsible for histological analysis|was responsible for drafting and revising the manuscript|was responsible for patient selection and clinical follow-up|was responsible for patient selection and clinical follow-up, and for drafting and revising the manuscript|was responsible for patient selection and clinical follow-up, and for drafting and revising the manuscript	was responsible for histological analysis	Performed the experiments	Investigation	YES
3636492	23730366	MD	2	was the principal investigator of the study and the corresponding author|was responsible for the design of the study, the performance of the cardiac catheterizations, the interpretation of data and the paper writing|was responsible for data interpretation and manuscript revision|was responsible for histological analysis|was responsible for drafting and revising the manuscript|was responsible for patient selection and clinical follow-up|was responsible for patient selection and clinical follow-up, and for drafting and revising the manuscript|was responsible for patient selection and clinical follow-up, and for drafting and revising the manuscript	was responsible for drafting and revising the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3636492	23730366	MD	2	was the principal investigator of the study and the corresponding author|was responsible for the design of the study, the performance of the cardiac catheterizations, the interpretation of data and the paper writing|was responsible for data interpretation and manuscript revision|was responsible for histological analysis|was responsible for drafting and revising the manuscript|was responsible for patient selection and clinical follow-up|was responsible for patient selection and clinical follow-up, and for drafting and revising the manuscript|was responsible for patient selection and clinical follow-up, and for drafting and revising the manuscript	was responsible for patient selection and clinical follow-up	-	-	NO
3636492	23730366	MD	2	was the principal investigator of the study and the corresponding author|was responsible for the design of the study, the performance of the cardiac catheterizations, the interpretation of data and the paper writing|was responsible for data interpretation and manuscript revision|was responsible for histological analysis|was responsible for drafting and revising the manuscript|was responsible for patient selection and clinical follow-up|was responsible for patient selection and clinical follow-up, and for drafting and revising the manuscript|was responsible for patient selection and clinical follow-up, and for drafting and revising the manuscript	was responsible for patient selection and clinical follow-up, and for drafting and revising the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3636492	23730366	MD	2	was the principal investigator of the study and the corresponding author|was responsible for the design of the study, the performance of the cardiac catheterizations, the interpretation of data and the paper writing|was responsible for data interpretation and manuscript revision|was responsible for histological analysis|was responsible for drafting and revising the manuscript|was responsible for patient selection and clinical follow-up|was responsible for patient selection and clinical follow-up, and for drafting and revising the manuscript|was responsible for patient selection and clinical follow-up, and for drafting and revising the manuscript	was responsible for patient selection and clinical follow-up, and for drafting and revising the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3636492	23730366	Manuel Lopez-Messeguer	2	was responsible for patient selection and clinical follow-up	was responsible for patient selection and clinical follow-up	-	-	NO
3636492	23730366	Maria Angeles Montero	2	was responsible for histological analysis	was responsible for histological analysis	Performed the experiments	Investigation	YES
3636492	23730366	Nadia Bouteldja	2	was responsible for patient selection and clinical follow-up, and for drafting and revising the manuscript	was responsible for patient selection and clinical follow-up, and for drafting and revising the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3636492	23730366	PhD	2	was the principal investigator of the study and the corresponding author|was responsible for the design of the study, the performance of the cardiac catheterizations, the interpretation of data and the paper writing	was the principal investigator of the study and the corresponding author	Conceived and designed the experiments|Wrote the paper	Conceptualization|Funding acquisition|Writing - Original Draft	YES
3636492	23730366	PhD	2	was the principal investigator of the study and the corresponding author|was responsible for the design of the study, the performance of the cardiac catheterizations, the interpretation of data and the paper writing	was responsible for the design of the study, the performance of the cardiac catheterizations, the interpretation of data and the paper writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology	YES
3636492	23730366	Rio Aguilar	2	was responsible for data interpretation and manuscript revision	was responsible for data interpretation and manuscript revision	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5385096	28390408	FM	2	defined the array content	defined the array content	Performed the experiments	Investigation	YES
5385096	28390408	GO	2	performed the microarray experiments	performed the microarray experiments	Performed the experiments	Investigation	YES
5385096	28390408	JB	2	developed pehm, implemented hervgdb4, designed the array, performed the analyses and wrote the paper	developed pehm, implemented hervgdb4, designed the array, performed the analyses and wrote the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5385096	28390408	JBV	2	provided advice on the bioinformatics and statistical aspects of the project	provided advice on the bioinformatics and statistical aspects of the project	Analyzed the data	Formal analysis	YES
5385096	28390408	NM	2	provided advice on the bioinformatics and statistical aspects of the project	provided advice on the bioinformatics and statistical aspects of the project	Analyzed the data	Formal analysis	YES
5385096	28390408	VM	2	performed the microarray experiments	performed the microarray experiments	Performed the experiments	Investigation	YES
5600969	28955369	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5600969	28955369	GB	PLoS52	collected the samples	collected the samples	Performed the experiments	Investigation	YES
5600969	28955369	GZ	PLoS52	conceived and designed the experiment	conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5600969	28955369	NK	PLoS52	helped to revise the paper	helped to revise the paper	Wrote the paper	Writing - Review & Editing	YES
5600969	28955369	TZ	PLoS52	performed the experiments and analyzed the data|helped to revise the paper	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5600969	28955369	TZ	PLoS52	performed the experiments and analyzed the data|helped to revise the paper	helped to revise the paper	Wrote the paper	Writing - Review & Editing	YES
5600969	28955369	XZ	PLoS52	conceived and designed the experiment|performed the experiments and analyzed the data|wrote the paper	conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5600969	28955369	XZ	PLoS52	conceived and designed the experiment|performed the experiments and analyzed the data|wrote the paper	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5600969	28955369	XZ	PLoS52	conceived and designed the experiment|performed the experiments and analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5600969	28955369	YZ	PLoS52	collected the samples	collected the samples	Performed the experiments	Investigation	YES
5824704	29503855	AT	2	assisted with calculations and reviewed the manuscript	assisted with calculations and reviewed the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5824704	29503855	CM	2	performed the pet phantom study and revised the manuscript	performed the pet phantom study and revised the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5824704	29503855	MB	2	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5824704	29503855	RS	2	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5824704	29503855	SB	2	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5824704	29503855	SJ	2	assisted with the separation, as well as the reduction processes	assisted with the separation, as well as the reduction processes	-	-	NO
5749171	29410914	Appolinaire Tiam	2	provided overall technical oversight for the study	provided overall technical oversight for the study	-	Supervision	YES
5749171	29410914	Heather J. Hoffman	2	analyzed the data and all authors contributed to the interpretation of the data	analyzed the data and all authors contributed to the interpretation of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5749171	29410914	Laura Guay	2	designed the study and wrote the protocol|provided overall technical oversight for the study	designed the study and wrote the protocol	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5749171	29410914	Laura Guay	2	designed the study and wrote the protocol|provided overall technical oversight for the study	provided overall technical oversight for the study	-	Supervision	YES
5749171	29410914	Lynne Mofenson	2	designed the study and wrote the protocol|provided overall technical oversight for the study	designed the study and wrote the protocol	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5749171	29410914	Lynne Mofenson	2	designed the study and wrote the protocol|provided overall technical oversight for the study	provided overall technical oversight for the study	-	Supervision	YES
5749171	29410914	Majoalane Mokone	2	collected data and/or provided oversight for study procedures	collected data and/or provided oversight for study procedures	Performed the experiments	Investigation|Supervision	YES
5749171	29410914	Mamakhetha Phalatse	2	provided overall technical oversight for the study	provided overall technical oversight for the study	-	Supervision	YES
5749171	29410914	Matsepeli Nchephe	2	provided overall technical oversight for the study	provided overall technical oversight for the study	-	Supervision	YES
5749171	29410914	Michelle M. Gill	2	designed the study and wrote the protocol|collected data and/or provided oversight for study procedures|wrote the original manuscript draft and all authors contributed to the final manuscript	designed the study and wrote the protocol	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5749171	29410914	Michelle M. Gill	2	designed the study and wrote the protocol|collected data and/or provided oversight for study procedures|wrote the original manuscript draft and all authors contributed to the final manuscript	collected data and/or provided oversight for study procedures	Performed the experiments	Investigation|Supervision	YES
5749171	29410914	Michelle M. Gill	2	designed the study and wrote the protocol|collected data and/or provided oversight for study procedures|wrote the original manuscript draft and all authors contributed to the final manuscript	wrote the original manuscript draft and all authors contributed to the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5749171	29410914	Vincent J. Tukei	2	collected data and/or provided oversight for study procedures	collected data and/or provided oversight for study procedures	Performed the experiments	Investigation|Supervision	YES
1762307	17183637	IK	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762307	17183637	IK	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762307	17183637	KF	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762307	17183637	MF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762307	17183637	MF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762307	17183637	MF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4529919	26273645	Hua Shi	2	were involved in drafting the paper	were involved in drafting the paper	Wrote the paper	Writing - Original Draft	YES
4529919	26273645	Jinjin Li	2	created the front end user interface and developed the web server	created the front end user interface and developed the web server	Contributed reagents/materials/analysis tools	Software	YES
4529919	26273645	Qingqi Hong	2	helped revise the paper and gave helpful suggestion	helped revise the paper and gave helpful suggestion	Wrote the paper	Writing - Review & Editing	YES
4529919	26273645	Quan Zou	2	analyzed data and designed the project and coordinated it	analyzed data and designed the project and coordinated it	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology|Project administration	YES
4529919	26273645	Ying Ju	2	had given final approval of the version to be published	had given final approval of the version to be published	-	-	NO
4529919	26273645	Yun Wu	2	were involved in drafting the paper	were involved in drafting the paper	Wrote the paper	Writing - Original Draft	YES
4408037	25905865	GCNF	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4408037	25905865	IAF	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4408037	25905865	JA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408037	25905865	JA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408037	25905865	JA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408037	25905865	JA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408037	25905865	JA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408037	25905865	JAL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408037	25905865	JAL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408037	25905865	JAL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408037	25905865	JHM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408037	25905865	JHM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408037	25905865	JHM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408037	25905865	JHM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408037	25905865	JHM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408037	25905865	JKK	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408037	25905865	JKK	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408037	25905865	JKK	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408037	25905865	KSA	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4408037	25905865	LCCG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408037	25905865	LCCG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408037	25905865	LCCG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408037	25905865	LCCG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408037	25905865	LCCG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408037	25905865	PLR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408037	25905865	PLR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408037	25905865	PLR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408037	25905865	PLR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5577707	28361501	Both authors	2	contributed equally and approved the final version	contributed equally and approved the final version	-	-	NO
5387192	28399811	HR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5387192	28399811	HR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
5387192	28399811	HR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5387192	28399811	HR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5387192	28399811	HS	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5387192	28399811	JP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
5387192	28399811	JP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5387192	28399811	MJ	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5387192	28399811	MdJ	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5387192	28399811	MdJ	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5387192	28399811	TB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5387192	28399811	TB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5387192	28399811	TB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5387192	28399811	UN	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
5387192	28399811	UN	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5387192	28399811	WE	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5387192	28399811	WdL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
5387192	28399811	WdL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762308	17205135	JS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762308	17205135	JS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762308	17205135	JS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762308	17205135	SD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762308	17205135	SD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762308	17205135	SD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762308	17205135	SD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5577712	28530045	BM	2	conducted the literature review, summarized relevant literature, and participated in the editing of the manuscript	conducted the literature review, summarized relevant literature, and participated in the editing of the manuscript	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
5577712	28530045	RV	2	provided the scientific leadership, conceptualized this review article, guided the literature review, led the drafting of the manuscript, and supervised all revisions	provided the scientific leadership, conceptualized this review article, guided the literature review, led the drafting of the manuscript, and supervised all revisions	Conceived and designed the experiments|Wrote the paper	Conceptualization|Formal analysis|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
5577712	28530045	SL	2	provided additional scientific leadership, drafted sections of the manuscript, and edited the manuscript	provided additional scientific leadership, drafted sections of the manuscript, and edited the manuscript	Wrote the paper	Supervision|Writing - Original Draft|Writing - Review & Editing	YES
5600998	28955360	BM	2	detected the changes of secondary metabolites of soybean roots	detected the changes of secondary metabolites of soybean roots	-	-	NO
5600998	28955360	R-RT	2	detected the changes of secondary metabolites of soybean roots	detected the changes of secondary metabolites of soybean roots	-	-	NO
5600998	28955360	T-HZ	2	guided the whole research as the corresponding author	guided the whole research as the corresponding author	-	Supervision	YES
5600998	28955360	UV-B	2	on root growth of soybean	on root growth of soybean	-	-	NO
5600998	28955360	YW	2	detected the changes of endogenous hormone of soybean roots	detected the changes of endogenous hormone of soybean roots	-	-	NO
5824707	29503857	ADG	2	jointly conceived the study	jointly conceived the study	Conceived and designed the experiments	Conceptualization	YES
5824707	29503857	JEB	2	jointly conceived the study|designed and coordinated the study|conducted the chemical synthesis|conducted the radiochemistry development and optimisation	jointly conceived the study	Conceived and designed the experiments	Conceptualization	YES
5824707	29503857	JEB	2	jointly conceived the study|designed and coordinated the study|conducted the chemical synthesis|conducted the radiochemistry development and optimisation	designed and coordinated the study	Conceived and designed the experiments	Methodology|Project administration	YES
5824707	29503857	JEB	2	jointly conceived the study|designed and coordinated the study|conducted the chemical synthesis|conducted the radiochemistry development and optimisation	conducted the chemical synthesis	Performed the experiments	Investigation	YES
5824707	29503857	JEB	2	jointly conceived the study|designed and coordinated the study|conducted the chemical synthesis|conducted the radiochemistry development and optimisation	conducted the radiochemistry development and optimisation	Performed the experiments	Investigation	YES
5824707	29503857	SFC	2	conducted the chemical synthesis|conducted the radiochemistry development and optimisation	conducted the chemical synthesis	Performed the experiments	Investigation	YES
5824707	29503857	SFC	2	conducted the chemical synthesis|conducted the radiochemistry development and optimisation	conducted the radiochemistry development and optimisation	Performed the experiments	Investigation	YES
4408038	25906026	CZSX	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4408038	25906026	CZSX	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4408038	25906026	TD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408038	25906026	TD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4408038	25906026	TD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408038	25906026	ZB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408038	25906026	ZB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408038	25906026	ZB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408038	25906026	ZB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762309	17183709	AA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762309	17183709	AA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762309	17183709	AA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762309	17183709	MT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762309	17183709	MT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762309	17183709	MT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762309	17183709	MT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762309	17183709	NG	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762309	17183709	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762309	17183709	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762309	17183709	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762309	17183709	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5387373	28399809	BX	2	performed the rna seq and data analysis|wrote the manuscript and approved the final manuscript	performed the rna seq and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5387373	28399809	BX	2	performed the rna seq and data analysis|wrote the manuscript and approved the final manuscript	wrote the manuscript and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5387373	28399809	JXS	2	conducted the measurement of anthocyanin content	conducted the measurement of anthocyanin content	Performed the experiments	Investigation	YES
5387373	28399809	LXF	2	performed qrt-pcr measurement and reviewed the manuscript	performed qrt-pcr measurement and reviewed the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5387373	28399809	LZ	2	designed the experiments|performed the rna seq and data analysis|wrote the manuscript and approved the final manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5387373	28399809	LZ	2	designed the experiments|performed the rna seq and data analysis|wrote the manuscript and approved the final manuscript	performed the rna seq and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5387373	28399809	LZ	2	designed the experiments|performed the rna seq and data analysis|wrote the manuscript and approved the final manuscript	wrote the manuscript and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5387373	28399809	MXW	2	conducted the measurement of anthocyanin content	conducted the measurement of anthocyanin content	Performed the experiments	Investigation	YES
5387373	28399809	TW	2	performed qrt-pcr measurement and reviewed the manuscript	performed qrt-pcr measurement and reviewed the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5387373	28399809	YFY	2	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5601038	28955353	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5601038	28955353	BC	2	revised the manucript	revised the manucript	Wrote the paper	Writing - Review & Editing	YES
5601038	28955353	GA	2	were involved in the sample collection	were involved in the sample collection	Performed the experiments	Investigation	YES
5601038	28955353	JJ	2	collected samples, generated data, and wrote a draft of the manuscript	collected samples, generated data, and wrote a draft of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5601038	28955353	SC	2	assisted data analysis	assisted data analysis	Analyzed the data	Formal analysis	YES
5601038	28955353	SJ	2	confirmed some data by repeating the qrt-pcr assay	confirmed some data by repeating the qrt-pcr assay	Performed the experiments	Investigation	YES
5601038	28955353	SR	2	conceived, designed, supervised the research, and made final revision of the manuscript	conceived, designed, supervised the research, and made final revision of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Supervision|Writing - Review & Editing	YES
4408040	25906323	CJS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408040	25906323	CJS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408040	25906323	CJS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408040	25906323	CJS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408040	25906323	CTC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408040	25906323	CTC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408040	25906323	CTC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408040	25906323	CTC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408040	25906323	DAMV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408040	25906323	DAMV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408040	25906323	DAMV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408040	25906323	DAMV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408040	25906323	FF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408040	25906323	FF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408040	25906323	FF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408040	25906323	FF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408040	25906323	GAG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408040	25906323	GAG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408040	25906323	GAG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408040	25906323	GAG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408040	25906323	RM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408040	25906323	RM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408040	25906323	RM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408040	25906323	RM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408040	25906323	RM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5824708	29503858	AJ	2	performed the biological experiments and their analysis	performed the biological experiments and their analysis	Performed the experiments	Investigation	YES
5824708	29503858	LOD	2	was involved in the design of the studies and performed all the synthetic chemical and radiochemical work, and their analysis|was also involved in writing the manuscript	was involved in the design of the studies and performed all the synthetic chemical and radiochemical work, and their analysis	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5824708	29503858	LOD	2	was involved in the design of the studies and performed all the synthetic chemical and radiochemical work, and their analysis|was also involved in writing the manuscript	was also involved in writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5824708	29503858	MB	2	was involved in the design of the studies, the analysis the results and the revision of the manuscript	was involved in the design of the studies, the analysis the results and the revision of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
5824708	29503858	RS	2	was involved in the design of the studies, the analysis the results and the revision of the manuscript	was involved in the design of the studies, the analysis the results and the revision of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
5824708	29503858	SMA	2	was involved in the design of the studies, the analysis the results and the revision of the manuscript	was involved in the design of the studies, the analysis the results and the revision of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
5850898	29682344	Biksegn Asrat	2	had a role in data review, data extraction, and writing and editing of this manuscript	had a role in data review, data extraction, and writing and editing of this manuscript	Analyzed the data|Wrote the paper	Data curation|Writing - Original Draft|Writing - Review & Editing	YES
5850898	29682344	Shegaye Shumet	2	had a role in data review, data extraction, and writing and editing of this manuscript	had a role in data review, data extraction, and writing and editing of this manuscript	Analyzed the data|Wrote the paper	Data curation|Writing - Original Draft|Writing - Review & Editing	YES
5850898	29682344	Tadele Amare	2	had a primary role in conceptualization, data review, data extraction, data analysis, and writing and editing of this manuscript	had a primary role in conceptualization, data review, data extraction, data analysis, and writing and editing of this manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Data curation|Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5850898	29682344	Wondale Getinet	2	had a role in data review, data extraction, and writing and editing of this manuscript	had a role in data review, data extraction, and writing and editing of this manuscript	Analyzed the data|Wrote the paper	Data curation|Writing - Original Draft|Writing - Review & Editing	YES
1762310	17183654	CR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762310	17183654	CR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762310	17183654	CR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762310	17183654	CR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762310	17183654	CR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762310	17183654	DS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762310	17183654	DS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762310	17183654	DS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762310	17183654	DS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762310	17183654	LR	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762310	17183654	LR	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408041	25906374	GM	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408041	25906374	GM	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4408041	25906374	JAC	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408041	25906374	JAC	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408041	25906374	JGV	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408041	25906374	JGV	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408041	25906374	JGV	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408041	25906374	LHD-C	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408041	25906374	LHD-C	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408041	25906374	MFVM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408041	25906374	MFVM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408041	25906374	MFVM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408041	25906374	RSH	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408041	25906374	RSH	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408041	25906374	RSH	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408041	25906374	TW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408041	25906374	TW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408041	25906374	TW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408041	25906374	TW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408041	25906374	TW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5388996	28403834	CC	2	participated in chromosome location and gene cluster identification	participated in chromosome location and gene cluster identification	Performed the experiments	Investigation	YES
5388996	28403834	CW	2	participated in protein structure and similarity analysis of nbs-encoding genes	participated in protein structure and similarity analysis of nbs-encoding genes	Performed the experiments	Investigation	YES
5388996	28403834	JL	2	participated in design of the study, data preparation and drafted the manuscript	participated in design of the study, data preparation and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5388996	28403834	XZ	2	participated in the sequence alignment and phylogenetic analysis	participated in the sequence alignment and phylogenetic analysis	Performed the experiments	Investigation	YES
5388996	28403834	YC	2	conceived of the study, and participated in its coordination and helped to draft the manuscript	conceived of the study, and participated in its coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Project administration|Writing - Original Draft	YES
1762311	17183713	GW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1762311	17183713	JM	PLoS5	Performed the experiments|Analyzed the data|Edited the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762311	17183713	JM	PLoS5	Performed the experiments|Analyzed the data|Edited the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762311	17183713	JM	PLoS5	Performed the experiments|Analyzed the data|Edited the paper	Edited the paper	Wrote the paper	Writing - Review & Editing	YES
1762311	17183713	TD	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762311	17183713	TK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1762311	17183713	ZJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762311	17183713	ZJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762311	17183713	ZJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5601039	28955363	AG-O	PLoS52	contributed in gene constructs	contributed in gene constructs	Performed the experiments	Investigation	YES
5601039	28955363	DL	PLoS52	helped in sirna analysis	helped in sirna analysis	-	-	NO
5601039	28955363	DW	PLoS52	contributed in tissue culture and tomato transformation	contributed in tissue culture and tomato transformation	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5601039	28955363	HE	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5601039	28955363	JA-N	PLoS52	contributed in data production	contributed in data production	Contributed reagents/materials/analysis tools	Resources	YES
5601039	28955363	ME	PLoS52	contributed in data production	contributed in data production	Contributed reagents/materials/analysis tools	Resources	YES
5601039	28955363	ND	PLoS52	performed the molecular work and transgenic analysis	performed the molecular work and transgenic analysis	Performed the experiments	Investigation	YES
5601039	28955363	RA	PLoS52	conceived, planned, and supervised the work	conceived, planned, and supervised the work	Conceived and designed the experiments	Conceptualization|Supervision	YES
5601039	28955363	SM	PLoS52	contributed in data production	contributed in data production	Contributed reagents/materials/analysis tools	Resources	YES
3691918	23844389	Bilal Haider Abbasi	7	Revised the whole manuscript	Revised the whole manuscript	Wrote the paper	Writing - Review & Editing	YES
3691918	23844389	Hina Fazal	7	study design, collection, identification and crude drug studies	study design, collection, identification and crude drug studies	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3691918	23844389	Nisar Ahmad	7	Palynological studies	Palynological studies	-	-	NO
4408042	25905797	AF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408042	25905797	AF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408042	25905797	AF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408042	25905797	AF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408042	25905797	AF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408042	25905797	CC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408042	25905797	CC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408042	25905797	CC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408042	25905797	CC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408042	25905797	EJL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408042	25905797	EJL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408042	25905797	EJL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408042	25905797	EJL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408042	25905797	JTW	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408042	25905797	JTW	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408042	25905797	MJG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408042	25905797	MJG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408042	25905797	MJG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408042	25905797	MJG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408042	25905797	MJG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408042	25905797	VLE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408042	25905797	VLE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408042	25905797	VLE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408042	25905797	VLE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4529923	26273634	Pingping Zhang	2	contributed equally	contributed equally	-	-	NO
4529923	26273634	Yikun Mou	2	contributed equally	contributed equally	-	-	NO
3899589	24459536	G. Vlachou	2	conducted and analyzed the data from this evaluation, and also drafted the manuscript	conducted and analyzed the data from this evaluation, and also drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3899589	24459536	I. Gerogianni	2	provided critical comments for the manuscript	provided critical comments for the manuscript	-	-	NO
3899589	24459536	K. Gourgoulianis	2	contributed to the concept and design of the study, and provided critical comments for the manuscript	contributed to the concept and design of the study, and provided critical comments for the manuscript	Conceived and designed the experiments	Conceptualization|Methodology	YES
3899589	24459536	V. Skoufaras	2	provided the questionnaire and assisted in data collection	provided the questionnaire and assisted in data collection	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5601040	28955377	FB	PLoS52	provided assistance	provided assistance	-	-	NO
5601040	28955377	GW	PLoS52	provided assistance	provided assistance	-	-	NO
5601040	28955377	HL	PLoS52	designed the experiments|analyzed the data	designed the experiments	Conceived and designed the experiments	Methodology	YES
5601040	28955377	HL	PLoS52	designed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5601040	28955377	HZ	PLoS52	designed the experiments|analyzed the data|wrote the manuscript and contributed to discussion	designed the experiments	Conceived and designed the experiments	Methodology	YES
5601040	28955377	HZ	PLoS52	designed the experiments|analyzed the data|wrote the manuscript and contributed to discussion	analyzed the data	Analyzed the data	Formal analysis	YES
5601040	28955377	HZ	PLoS52	designed the experiments|analyzed the data|wrote the manuscript and contributed to discussion	wrote the manuscript and contributed to discussion	Wrote the paper	Writing - Original Draft	YES
5601040	28955377	TT	PLoS52	designed the experiments|performed major of the study|analyzed the data|wrote the manuscript and contributed to discussion	designed the experiments	Conceived and designed the experiments	Methodology	YES
5601040	28955377	TT	PLoS52	designed the experiments|performed major of the study|analyzed the data|wrote the manuscript and contributed to discussion	performed major of the study	Performed the experiments	Investigation	YES
5601040	28955377	TT	PLoS52	designed the experiments|performed major of the study|analyzed the data|wrote the manuscript and contributed to discussion	analyzed the data	Analyzed the data	Formal analysis	YES
5601040	28955377	TT	PLoS52	designed the experiments|performed major of the study|analyzed the data|wrote the manuscript and contributed to discussion	wrote the manuscript and contributed to discussion	Wrote the paper	Writing - Original Draft	YES
5601040	28955377	XP	PLoS52	provided assistance	provided assistance	-	-	NO
5601040	28955377	YH	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5601040	28955377	YS	PLoS52	provided assistance	provided assistance	-	-	NO
1762312	17183635	AS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1762312	17183635	CL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1762312	17183635	EO	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1762312	17183635	FL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1762312	17183635	JC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1762312	17183635	MM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1762312	17183635	RD	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5765470	29023748	All authors	2	had full access to all the data in the study and confirm that it is an honest, accurate and transparent account of the study being reported|edited the report and approved the final version	had full access to all the data in the study and confirm that it is an honest, accurate and transparent account of the study being reported	Analyzed the data	Data curation	YES
5765470	29023748	All authors	2	had full access to all the data in the study and confirm that it is an honest, accurate and transparent account of the study being reported|edited the report and approved the final version	edited the report and approved the final version	Wrote the paper	Writing - Review & Editing	YES
5765470	29023748	MSG	2	programmed the microsimulation model	programmed the microsimulation model	Performed the experiments|Contributed reagents/materials/analysis tools	Formal analysis|Methodology|Software	YES
5765470	29023748	PDS	2	conceived and designed the work	conceived and designed the work	Conceived and designed the experiments	Conceptualization	YES
5765470	29023748	PW	2	programmed the microsimulation model	programmed the microsimulation model	Performed the experiments|Contributed reagents/materials/analysis tools	Formal analysis|Methodology|Software	YES
5765470	29023748	RL	2	designed the microsimulation model, interpreted the results and prepared the first draft of the manuscript|had final responsibility for the decision to submit for publication	designed the microsimulation model, interpreted the results and prepared the first draft of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5765470	29023748	RL	2	designed the microsimulation model, interpreted the results and prepared the first draft of the manuscript|had final responsibility for the decision to submit for publication	had final responsibility for the decision to submit for publication	-	-	NO
5389087	28403820	AGW	2	participated in the result interpretation and paper revision	participated in the result interpretation and paper revision	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5389087	28403820	AP	2	participated in the result interpretation and paper revision	participated in the result interpretation and paper revision	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5389087	28403820	CN	2	participated in the result interpretation and paper revision	participated in the result interpretation and paper revision	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5389087	28403820	JCJ	2	performed the experiments, analyzed the data, and prepared the manuscript	performed the experiments, analyzed the data, and prepared the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5389087	28403820	JFL	2	conceived and designed the experiments, and prepared the manuscript	conceived and designed the experiments, and prepared the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
5389087	28403820	JLF	2	participated in the result interpretation and paper revision	participated in the result interpretation and paper revision	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5389087	28403820	RM	2	participated in the result interpretation and paper revision	participated in the result interpretation and paper revision	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5389087	28403820	XTF	2	performed the experiments, analyzed the data, and prepared the manuscript	performed the experiments, analyzed the data, and prepared the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5577716	28770592	AV	2	provided comments on first and subsequent drafts	provided comments on first and subsequent drafts	Wrote the paper	Writing - Original Draft	YES
5577716	28770592	RB	2	provided comments on first and subsequent drafts	provided comments on first and subsequent drafts	Wrote the paper	Writing - Original Draft	YES
5577716	28770592	VM	2	developed the original and final draft	developed the original and final draft	Wrote the paper	Writing - Original Draft	YES
5824710	29503860	JFWN	1	Substantial contributions to the conception or design of the work|Analysis and interpretation of data for the work|Critical revision of the work for important intellectual content|Final approval of the version to be published|Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Substantial contributions to the conception or design of the work	Conceived and designed the experiments	Conceptualization	YES
5824710	29503860	JFWN	1	Substantial contributions to the conception or design of the work|Analysis and interpretation of data for the work|Critical revision of the work for important intellectual content|Final approval of the version to be published|Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Analysis and interpretation of data for the work	Analyzed the data	Formal analysis	YES
5824710	29503860	JFWN	1	Substantial contributions to the conception or design of the work|Analysis and interpretation of data for the work|Critical revision of the work for important intellectual content|Final approval of the version to be published|Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Critical revision of the work for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5824710	29503860	JFWN	1	Substantial contributions to the conception or design of the work|Analysis and interpretation of data for the work|Critical revision of the work for important intellectual content|Final approval of the version to be published|Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Final approval of the version to be published	-	-	NO
5824710	29503860	JFWN	1	Substantial contributions to the conception or design of the work|Analysis and interpretation of data for the work|Critical revision of the work for important intellectual content|Final approval of the version to be published|Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	-	-	NO
5824710	29503860	LRP	1	Substantial contributions to the conception or design of the work|Acquisition of data|Analysis and interpretation of data for the work|Critical revision of the work for important intellectual content|Final approval of the version to be published|Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Substantial contributions to the conception or design of the work	Conceived and designed the experiments	Conceptualization	YES
5824710	29503860	LRP	1	Substantial contributions to the conception or design of the work|Acquisition of data|Analysis and interpretation of data for the work|Critical revision of the work for important intellectual content|Final approval of the version to be published|Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Acquisition of data	Performed the experiments	Investigation	YES
5824710	29503860	LRP	1	Substantial contributions to the conception or design of the work|Acquisition of data|Analysis and interpretation of data for the work|Critical revision of the work for important intellectual content|Final approval of the version to be published|Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Analysis and interpretation of data for the work	Analyzed the data	Formal analysis	YES
5824710	29503860	LRP	1	Substantial contributions to the conception or design of the work|Acquisition of data|Analysis and interpretation of data for the work|Critical revision of the work for important intellectual content|Final approval of the version to be published|Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Critical revision of the work for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5824710	29503860	LRP	1	Substantial contributions to the conception or design of the work|Acquisition of data|Analysis and interpretation of data for the work|Critical revision of the work for important intellectual content|Final approval of the version to be published|Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Final approval of the version to be published	-	-	NO
5824710	29503860	LRP	1	Substantial contributions to the conception or design of the work|Acquisition of data|Analysis and interpretation of data for the work|Critical revision of the work for important intellectual content|Final approval of the version to be published|Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	-	-	NO
5824710	29503860	MAS	1	Substantial contributions to the conception or design of the work|Acquisition of data|Analysis and interpretation of data for the work|Drafting of the work|Final approval of the version to be published|Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Substantial contributions to the conception or design of the work	Conceived and designed the experiments	Conceptualization	YES
5824710	29503860	MAS	1	Substantial contributions to the conception or design of the work|Acquisition of data|Analysis and interpretation of data for the work|Drafting of the work|Final approval of the version to be published|Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Acquisition of data	Performed the experiments	Investigation	YES
5824710	29503860	MAS	1	Substantial contributions to the conception or design of the work|Acquisition of data|Analysis and interpretation of data for the work|Drafting of the work|Final approval of the version to be published|Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Analysis and interpretation of data for the work	Analyzed the data	Formal analysis	YES
5824710	29503860	MAS	1	Substantial contributions to the conception or design of the work|Acquisition of data|Analysis and interpretation of data for the work|Drafting of the work|Final approval of the version to be published|Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Drafting of the work	Wrote the paper	Writing - Original Draft	YES
5824710	29503860	MAS	1	Substantial contributions to the conception or design of the work|Acquisition of data|Analysis and interpretation of data for the work|Drafting of the work|Final approval of the version to be published|Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Final approval of the version to be published	-	-	NO
5824710	29503860	MAS	1	Substantial contributions to the conception or design of the work|Acquisition of data|Analysis and interpretation of data for the work|Drafting of the work|Final approval of the version to be published|Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	-	-	NO
4408043	25905725	AS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Obtained funding|Study supervision	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408043	25905725	AS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Obtained funding|Study supervision	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408043	25905725	AS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Obtained funding|Study supervision	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408043	25905725	AS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Obtained funding|Study supervision	Obtained funding	-	Funding acquisition	YES
4408043	25905725	AS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Obtained funding|Study supervision	Study supervision	-	Supervision	YES
4408043	25905725	BK	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408043	25905725	BK	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408043	25905725	CB	PLoS5	Wrote the paper|Obtained funding	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408043	25905725	CB	PLoS5	Wrote the paper|Obtained funding	Obtained funding	-	Funding acquisition	YES
4408043	25905725	DC	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408043	25905725	DC	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408043	25905725	FA	PLoS5	Wrote the paper|Obtained funding	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408043	25905725	FA	PLoS5	Wrote the paper|Obtained funding	Obtained funding	-	Funding acquisition	YES
4408043	25905725	IG	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408043	25905725	IG	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408043	25905725	IG	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408043	25905725	JM	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper|Obtained funding|Administrative, technical, or material support	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408043	25905725	JM	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper|Obtained funding|Administrative, technical, or material support	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408043	25905725	JM	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper|Obtained funding|Administrative, technical, or material support	Obtained funding	-	Funding acquisition	YES
4408043	25905725	JM	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper|Obtained funding|Administrative, technical, or material support	Administrative, technical, or material support	Performed the experiments	Investigation|Project administration	YES
4408043	25905725	LM	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408043	25905725	LM	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408043	25905725	SS	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408043	25905725	VDL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Obtained funding|Administrative, technical, or material support|Study supervision	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408043	25905725	VDL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Obtained funding|Administrative, technical, or material support|Study supervision	Performed the experiments	Performed the experiments	Investigation	YES
4408043	25905725	VDL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Obtained funding|Administrative, technical, or material support|Study supervision	Analyzed the data	Analyzed the data	Formal analysis	YES
4408043	25905725	VDL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Obtained funding|Administrative, technical, or material support|Study supervision	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408043	25905725	VDL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Obtained funding|Administrative, technical, or material support|Study supervision	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408043	25905725	VDL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Obtained funding|Administrative, technical, or material support|Study supervision	Obtained funding	-	Funding acquisition	YES
4408043	25905725	VDL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Obtained funding|Administrative, technical, or material support|Study supervision	Administrative, technical, or material support	Performed the experiments	Investigation|Project administration	YES
4408043	25905725	VDL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Obtained funding|Administrative, technical, or material support|Study supervision	Study supervision	-	Supervision	YES
4952056	27435596	All authors	2	assisted with drafting the manuscript and approved the final draft	assisted with drafting the manuscript and approved the final draft	Wrote the paper	Writing - Original Draft	YES
4952056	27435596	DCHS	2	participated in conception and design of the study and revising the manuscript critically for intellectual content	participated in conception and design of the study and revising the manuscript critically for intellectual content	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
4952056	27435596	HZ	2	is the principal investigator of the dchs and assisted with conception and manuscript revisions	is the principal investigator of the dchs and assisted with conception and manuscript revisions	Conceived and designed the experiments|Wrote the paper	Conceptualization|Funding acquisition|Writing - Review & Editing	YES
4952056	27435596	KB	2	performed the statistical analysis and assisted with data interpretation	performed the statistical analysis and assisted with data interpretation	Analyzed the data	Formal analysis	YES
4952056	27435596	KS	2	contributed to concept and design and revising the manuscript critically for intellectual content	contributed to concept and design and revising the manuscript critically for intellectual content	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
4952056	27435596	WB	2	contributed to conception and design, data acquisition and interpretation and drafted the manuscript	contributed to conception and design, data acquisition and interpretation and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Resources|Writing - Original Draft	YES
5960566	29854445	Emily E. Pisarski	2	coordinated data collection and provided supervision to the ugandan research assistants	coordinated data collection and provided supervision to the ugandan research assistants	Performed the experiments	Investigation|Project administration|Supervision	YES
5960566	29854445	Jacqueline Karuhanga	2	collected the interview data	collected the interview data	Performed the experiments	Investigation	YES
5960566	29854445	John Bosco Tumuhairwe	2	collected the interview data	collected the interview data	Performed the experiments	Investigation	YES
5960566	29854445	Justin Brantley	2	helped coordinate the qualitative study and the linkages study intervention trial	helped coordinate the qualitative study and the linkages study intervention trial	-	Project administration	YES
5960566	29854445	Justine Abenaitwe	2	collected the interview data	collected the interview data	Performed the experiments	Investigation	YES
5960566	29854445	Meighan Krows	2	helped coordinate the qualitative study and the linkages study intervention trial	helped coordinate the qualitative study and the linkages study intervention trial	-	Project administration	YES
5960566	29854445	Melanie Tam	2	coordinated data collection and provided supervision to the ugandan research assistants	coordinated data collection and provided supervision to the ugandan research assistants	Performed the experiments	Investigation|Project administration|Supervision	YES
5960566	29854445	Robert Baijuka	2	collected the interview data	collected the interview data	Performed the experiments	Investigation	YES
5960566	29854445	Torin Schaafsma	2	helped coordinate the qualitative study and the linkages study intervention trial	helped coordinate the qualitative study and the linkages study intervention trial	-	Project administration	YES
5601042	28955355	D-DL	1	The experiments were performed by|The data were analyzed by|The paper was written by	The experiments were performed by	Performed the experiments	Investigation	YES
5601042	28955355	D-DL	1	The experiments were performed by|The data were analyzed by|The paper was written by	The data were analyzed by	Analyzed the data	Formal analysis	YES
5601042	28955355	D-DL	1	The experiments were performed by|The data were analyzed by|The paper was written by	The paper was written by	Wrote the paper	Writing - Original Draft	YES
5601042	28955355	J-SX	1	The data were analyzed by|The paper was written by	The data were analyzed by	Analyzed the data	Formal analysis	YES
5601042	28955355	J-SX	1	The data were analyzed by|The paper was written by	The paper was written by	Wrote the paper	Writing - Original Draft	YES
5601042	28955355	JZ	1	The experiments were performed by|The data were analyzed by	The experiments were performed by	Performed the experiments	Investigation	YES
5601042	28955355	JZ	1	The experiments were performed by|The data were analyzed by	The data were analyzed by	Analyzed the data	Formal analysis	YES
5601042	28955355	Z-NY	1	The experiments were conceived and designed by|The paper was written by	The experiments were conceived and designed by	Conceived and designed the experiments	Conceptualization|Methodology	YES
5601042	28955355	Z-NY	1	The experiments were conceived and designed by|The paper was written by	The paper was written by	Wrote the paper	Writing - Original Draft	YES
1762313	17183658	GH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1762313	17183658	HL	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762313	17183658	MB	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762313	17183658	MR	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762313	17183658	MR	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762313	17183658	MR	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762313	17183658	SK	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762313	17183658	SK	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408044	25906167	AW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4408044	25906167	CM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408044	25906167	CM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408044	25906167	CM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408044	25906167	KI	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408044	25906167	KI	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408044	25906167	NS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4408044	25906167	TO	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4408044	25906167	YN	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408044	25906167	YN	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4408044	25906167	YT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408044	25906167	YT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408044	25906167	YT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408044	25906167	YT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5813224	29055107	All authors	2	critically reviewed the article before submission	critically reviewed the article before submission	Wrote the paper	Writing - Review & Editing	YES
5813224	29055107	CS	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5813224	29055107	DN	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5813224	29055107	DPE	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5813224	29055107	DV	2	designed experiments and analyzed data	designed experiments and analyzed data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5813224	29055107	EP	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5813224	29055107	FA	2	designed experiments and analyzed data|wrote the article	designed experiments and analyzed data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5813224	29055107	FA	2	designed experiments and analyzed data|wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
5813224	29055107	GC	2	performed experiments|designed experiments and analyzed data	performed experiments	Performed the experiments	Investigation	YES
5813224	29055107	GC	2	performed experiments|designed experiments and analyzed data	designed experiments and analyzed data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5813224	29055107	HK	2	performed experiments|designed experiments and analyzed data	performed experiments	Performed the experiments	Investigation	YES
5813224	29055107	HK	2	performed experiments|designed experiments and analyzed data	designed experiments and analyzed data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5813224	29055107	PDB	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5813224	29055107	RB	2	designed experiments and analyzed data	designed experiments and analyzed data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5813224	29055107	SC	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5813224	29055107	ST	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5813224	29055107	WG	2	performed experiments|designed experiments and analyzed data|wrote the article	performed experiments	Performed the experiments	Investigation	YES
5813224	29055107	WG	2	performed experiments|designed experiments and analyzed data|wrote the article	designed experiments and analyzed data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5813224	29055107	WG	2	performed experiments|designed experiments and analyzed data|wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
5389088	28403814	A.A.	2	performed ngs library preparation and generated genomics data	performed ngs library preparation and generated genomics data	Performed the experiments	Investigation	YES
5389088	28403814	A.S.	2	conducted experiments with plants and fungal isolates and prepared biological material for genomic analyses	conducted experiments with plants and fungal isolates and prepared biological material for genomic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5389088	28403814	E.A.	2	conceived the original research, supervised data generation and analyses and wrote the manuscript	conceived the original research, supervised data generation and analyses and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Supervision|Writing - Original Draft	YES
5389088	28403814	F.H.	2	helped with bioinformatical data analyses	helped with bioinformatical data analyses	Analyzed the data	Formal analysis	YES
5389088	28403814	H.L.	2	helped with ngs library preparation and initial data analyses	helped with ngs library preparation and initial data analyses	Analyzed the data	Formal analysis	YES
5389088	28403814	R.L.B.	2	conducted experiments with plants and fungal isolates and prepared biological material for genomic analyses	conducted experiments with plants and fungal isolates and prepared biological material for genomic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5389088	28403814	S.W.	2	helped with initial bioinformatical data analyses and genome annotation	helped with initial bioinformatical data analyses and genome annotation	Analyzed the data	Data curation|Formal analysis	YES
5389088	28403814	W.B.R.	2	conducted bioinformatical data analyses, performed validation of candidate genes and wrote the manuscript	conducted bioinformatical data analyses, performed validation of candidate genes and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Validation|Writing - Original Draft	YES
4974808	27491390	MAG	2	is responsible for the idea and drafting the paper	is responsible for the idea and drafting the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4974808	27491390	OB	2	is responsible for drafting the paper	is responsible for drafting the paper	Wrote the paper	Writing - Original Draft	YES
1762314	17183694	DH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762314	17183694	DH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762314	17183694	DH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762314	17183694	DH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762314	17183694	JE	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762314	17183694	JE	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762314	17183694	NP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1762314	17183694	NP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5601043	28955371	All authors	2	contributed to final version of the manuscript	contributed to final version of the manuscript	-	-	NO
5601043	28955371	BV-A	2	collaborated in the biochemical and molecular analyses	collaborated in the biochemical and molecular analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5601043	28955371	ID	2	conceived the research|participated in the design, the acquisition, analysis, or interpretation of data for the work	conceived the research	Conceived and designed the experiments	Conceptualization	YES
5601043	28955371	ID	2	conceived the research|participated in the design, the acquisition, analysis, or interpretation of data for the work	participated in the design, the acquisition, analysis, or interpretation of data for the work	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5601043	28955371	MD-M	2	performed most of the experimental research|participated in the design, the acquisition, analysis, or interpretation of data for the work	performed most of the experimental research	Performed the experiments	Investigation	YES
5601043	28955371	MD-M	2	performed most of the experimental research|participated in the design, the acquisition, analysis, or interpretation of data for the work	participated in the design, the acquisition, analysis, or interpretation of data for the work	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5601043	28955371	MES	2	participated in the mite-barley assays	participated in the mite-barley assays	Performed the experiments	Investigation	YES
5601043	28955371	MM	2	conceived the research|participated in the design, the acquisition, analysis, or interpretation of data for the work	conceived the research	Conceived and designed the experiments	Conceptualization	YES
5601043	28955371	MM	2	conceived the research|participated in the design, the acquisition, analysis, or interpretation of data for the work	participated in the design, the acquisition, analysis, or interpretation of data for the work	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4994237	27550215	RdM	2	literature search, data extraction from papers and suggestions for information sequence on text	literature search, data extraction from papers and suggestions for information sequence on text	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5835975	29527563	AP	2	planned and carried out the synthesis and evaluation of the compounds	planned and carried out the synthesis and evaluation of the compounds	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5835975	29527563	HJW	2	helped analyzing and interpreting the data and initiated and designed the study	helped analyzing and interpreting the data and initiated and designed the study	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
5835975	29527563	MScho	2	participated in the design of the study, contributed to data interpretation and revised the manuscript	participated in the design of the study, contributed to data interpretation and revised the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
5835975	29527563	TO	2	contributed to syntheses and revised the manuscript	contributed to syntheses and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
6011175	29983999	Monica A. Magadi	2	provided technical guidance to the conceptualization and analysis and revised the draft paper	provided technical guidance to the conceptualization and analysis and revised the draft paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
6011175	29983999	Patrick Igulot	2	conceptualized the study, performed analysis, and drafted the article	conceptualized the study, performed analysis, and drafted the article	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
4408046	25905721	AA	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408046	25905721	AA	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408046	25905721	BE	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408046	25905721	BE	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408046	25905721	BE	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408046	25905721	BG	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408046	25905721	BG	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408046	25905721	BG	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408046	25905721	BV	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408046	25905721	BV	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408046	25905721	GH	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408046	25905721	GH	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408046	25905721	JM	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408046	25905721	JM	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408046	25905721	KG	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408046	25905721	KG	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408046	25905721	KG	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408046	25905721	KH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408046	25905721	KH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408046	25905721	KH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408046	25905721	KH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408046	25905721	KH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408046	25905721	MF	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408046	25905721	MF	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408046	25905721	MF	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408046	25905721	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408046	25905721	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408046	25905721	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408046	25905721	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408046	25905721	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408046	25905721	MW	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408046	25905721	MW	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408046	25905721	QL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408046	25905721	QL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408046	25905721	QL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408046	25905721	QL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408046	25905721	QL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408046	25905721	RB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408046	25905721	RB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408046	25905721	RB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408046	25905721	RB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408046	25905721	SG	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408046	25905721	XT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408046	25905721	XT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408046	25905721	XT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408046	25905721	XT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408046	25905721	XT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408046	25905721	YT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408046	25905721	YT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408046	25905721	YT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408046	25905721	YT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5389105	28403821	Caitlin Farris	2	was responsible for tissue collection	was responsible for tissue collection	-	-	NO
5389105	28403821	HCC	2	was responsible for processing of raw rna seq reads and initial rna seq analysis	was responsible for processing of raw rna seq reads and initial rna seq analysis	Performed the experiments	Investigation	YES
5389105	28403821	JAK	2	conceived the study, analyzed and interpreted data|were responsible for writing the manuscript	conceived the study, analyzed and interpreted data	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
5389105	28403821	JAK	2	conceived the study, analyzed and interpreted data|were responsible for writing the manuscript	were responsible for writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5389105	28403821	KN	2	was responsible for maintaining lines, tissue collection and qpcr	was responsible for maintaining lines, tissue collection and qpcr	Performed the experiments	Investigation	YES
5389105	28403821	NP	2	was responsible for the tissue collection and rna isolation for sequencing	was responsible for the tissue collection and rna isolation for sequencing	Performed the experiments	Investigation	YES
5389105	28403821	SQS	2	was instrumental in analysis and data interpretation, and contributed to the writing of the manuscript	was instrumental in analysis and data interpretation, and contributed to the writing of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5389105	28403821	SRC	2	was responsible for experimental and bioinformatics analysis and interpretation of rna seq data|were responsible for writing the manuscript	was responsible for experimental and bioinformatics analysis and interpretation of rna seq data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5389105	28403821	SRC	2	was responsible for experimental and bioinformatics analysis and interpretation of rna seq data|were responsible for writing the manuscript	were responsible for writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5022156	27624701	CBS	2	edited the paper	edited the paper	Wrote the paper	Writing - Review & Editing	YES
5022156	27624701	ET	2	wrote the first drafts of the paper	wrote the first drafts of the paper	Wrote the paper	Writing - Original Draft	YES
5577721	28361502	All authors	2	contributed to and approve of the final submission of the manuscript	contributed to and approve of the final submission of the manuscript	-	-	NO
5577721	28361502	CK	2	revised the manuscript for important intellectual content	revised the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5577721	28361502	HS	2	developed the initial draft of the manuscript	developed the initial draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
5577721	28361502	JD	2	revised the manuscript for important intellectual content	revised the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5577721	28361502	MN	2	revised the manuscript for important intellectual content	revised the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
1762315	17183728	HT	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762315	17183728	IU	PLoS5	Made discussions	Made discussions	-	-	NO
1762315	17183728	TA	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762315	17183728	TA	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762315	17183728	TY	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762315	17183728	TY	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762315	17183728	YH	PLoS5	Performed the experiments|Made discussions	Performed the experiments	Performed the experiments	Investigation	YES
1762315	17183728	YH	PLoS5	Performed the experiments|Made discussions	Made discussions	-	-	NO
5601045	28955373	CW	PLoS52	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5601045	28955373	HS	PLoS52	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5601045	28955373	JD	PLoS52	performed the experiments and analyzed the data|wrote the paper	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5601045	28955373	JD	PLoS52	performed the experiments and analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5601045	28955373	QY	PLoS52	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5601045	28955373	SH	PLoS52	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5601045	28955373	XS	PLoS52	conceived and designed the study|wrote the paper	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5601045	28955373	XS	PLoS52	conceived and designed the study|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5601045	28955373	YoY	PLoS52	conceived and designed the study|wrote the paper	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5601045	28955373	YoY	PLoS52	conceived and designed the study|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5601045	28955373	YuY	PLoS52	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5601045	28955373	all authors	PLoS52	have read and approved the final version	have read and approved the final version	-	-	NO
1762316	17183639	AM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762316	17183639	AM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762316	17183639	AM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762316	17183639	HM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1762316	17183639	IK	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762316	17183639	IK	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762316	17183639	IK	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762316	17183639	JJ	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762316	17183639	JN	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762316	17183639	JN	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762316	17183639	KA	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762316	17183639	KA	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762316	17183639	KA	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762316	17183639	LA	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762316	17183639	MW	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762316	17183639	PL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762316	17183639	PL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762316	17183639	PL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762316	17183639	SK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1762316	17183639	SY	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762316	17183639	SY	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762316	17183639	SY	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5835976	29527564	AG	2	carried out the synthesis of the peptides, the cold chelation with gallium, and the affinity studies and helped to draft the manuscript	carried out the synthesis of the peptides, the cold chelation with gallium, and the affinity studies and helped to draft the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5835976	29527564	DLG	2	conceived the study and helped to draft the manuscript	conceived the study and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5835976	29527564	FR	2	conceived the study and helped to draft the manuscript	conceived the study and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5835976	29527564	KBA	2	carried out the imaging studies, autoradiography and helped to draft the manuscript	carried out the imaging studies, autoradiography and helped to draft the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Investigation|Visualization|Writing - Original Draft	YES
5835976	29527564	PK	2	conceived the study and helped to draft the manuscript	conceived the study and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5835976	29527564	RBA	2	carried out and designed radiochemistry, stability studies, helped to the in vivo studies and drafted the manuscript	carried out and designed radiochemistry, stability studies, helped to the in vivo studies and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5835976	29527564	WG	2	participated in designing the study	participated in designing the study	Conceived and designed the experiments	Methodology	YES
5577723	28530039	CLG	2	extracted data, reviewed and revised the manuscript	extracted data, reviewed and revised the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5577723	28530039	CT	2	extracted data, reviewed and revised the manuscript	extracted data, reviewed and revised the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5577723	28530039	DD	2	extracted data, reviewed and revised the manuscript	extracted data, reviewed and revised the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5577723	28530039	VL	2	designed, and wrote the manuscript	designed, and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
4408047	25905494	AG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408047	25905494	AG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408047	25905494	AG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408047	25905494	FMS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4408047	25905494	FP	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408047	25905494	FP	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408047	25905494	HV	PLoS5	Performed the experiments|Personally interacted with patients	Performed the experiments	Performed the experiments	Investigation	YES
4408047	25905494	HV	PLoS5	Performed the experiments|Personally interacted with patients	Personally interacted with patients	-	-	NO
4408047	25905494	LA	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408047	25905494	LA	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408047	25905494	NC	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408047	25905494	SA	PLoS5	Performed the experiments|Personally interacted with patients	Performed the experiments	Performed the experiments	Investigation	YES
4408047	25905494	SA	PLoS5	Performed the experiments|Personally interacted with patients	Personally interacted with patients	-	-	NO
4408047	25905494	SV	PLoS5	Performed the experiments|Personally interacted with patients	Performed the experiments	Performed the experiments	Investigation	YES
4408047	25905494	SV	PLoS5	Performed the experiments|Personally interacted with patients	Personally interacted with patients	-	-	NO
4408047	25905494	VT	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408047	25905494	VT	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5389150	28403818	AS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5389150	28403818	AS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5389150	28403818	CCS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5389150	28403818	CCS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5389150	28403818	CCS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5389150	28403818	CCS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5389150	28403818	FMS	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5389150	28403818	FMS	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5389150	28403818	LK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5389150	28403818	LK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5389150	28403818	MHV	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5389150	28403818	MHV	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5389150	28403818	PAGF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5389150	28403818	PAGF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
5389150	28403818	PAGF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5389150	28403818	PAGF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5389150	28403818	RSAS	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5389150	28403818	RSAS	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5028939	27646569	AM	2	were responsible for data collection	were responsible for data collection	Performed the experiments	Investigation	YES
5028939	27646569	JG	2	was responsible for study idea, development, design, and revision and critical review of the manuscript	was responsible for study idea, development, design, and revision and critical review of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5028939	27646569	KB	2	were responsible for data collection	were responsible for data collection	Performed the experiments	Investigation	YES
5028939	27646569	MD	2	were responsible for data collection	were responsible for data collection	Performed the experiments	Investigation	YES
1762317	17183675	AG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762317	17183675	AG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762317	17183675	AG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762317	17183675	AG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762317	17183675	EF	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762317	17183675	GP	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762317	17183675	GS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762317	17183675	HC	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762317	17183675	HC	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762317	17183675	JE	PLoS5	Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762317	17183675	JE	PLoS5	Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762317	17183675	KT	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762317	17183675	LC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762317	17183675	PF	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762317	17183675	PS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1762317	17183675	PS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1762317	17183675	PS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5601048	28955362	GP	1	Conception of the research, analyzing data, manuscript draft and final approval	Conception of the research, analyzing data, manuscript draft and final approval	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
5601048	28955362	KH	1	Conception of the research, analyzing data, manuscript draft and final approval	Conception of the research, analyzing data, manuscript draft and final approval	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
5601048	28955362	RG	1	Conception of the research, analyzing data, manuscript draft and final approval	Conception of the research, analyzing data, manuscript draft and final approval	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
1762318	17183711	BS	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762318	17183711	BS	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1762318	17183711	CW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762318	17183711	CW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762318	17183711	CZ	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1762318	17183711	CZ	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762318	17183711	DF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762318	17183711	DF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762318	17183711	DF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762318	17183711	HL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1762318	17183711	SG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762318	17183711	SG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762318	17183711	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762318	17183711	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762318	17183711	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762318	17183711	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762318	17183711	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762318	17183711	SW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762318	17183711	SW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762318	17183711	SW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762318	17183711	SW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762318	17183711	TY	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762318	17183711	TY	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762318	17183711	WS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762318	17183711	WS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762318	17183711	WS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762318	17183711	YL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762318	17183711	YL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762318	17183711	YL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5969244	29417587	AG	2	contributed to the histopathological characterisation of lymphoid aggregates in gastric tissue	contributed to the histopathological characterisation of lymphoid aggregates in gastric tissue	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5969244	29417587	BJJ	2	designed the study and wrote the manuscript	designed the study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5969244	29417587	DGH	2	contributed to the histopathological characterisation of lymphoid aggregates in gastric tissue	contributed to the histopathological characterisation of lymphoid aggregates in gastric tissue	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5969244	29417587	GWJ	2	designed the study and wrote the manuscript|contributed to the histopathological characterisation of lymphoid aggregates in gastric tissue	designed the study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5969244	29417587	GWJ	2	designed the study and wrote the manuscript|contributed to the histopathological characterisation of lymphoid aggregates in gastric tissue	contributed to the histopathological characterisation of lymphoid aggregates in gastric tissue	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5969244	29417587	HG	2	performed bioinformatics analysis using the cancer genome atlas data sets	performed bioinformatics analysis using the cancer genome atlas data sets	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5969244	29417587	HO	2	performed laser microdissection	performed laser microdissection	Performed the experiments	Investigation	YES
5969244	29417587	LM	2	contributed to the histopathological characterisation of lymphoid aggregates in gastric tissue	contributed to the histopathological characterisation of lymphoid aggregates in gastric tissue	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5969244	29417587	LY	2	performed bioinformatics analysis using the cancer genome atlas data sets	performed bioinformatics analysis using the cancer genome atlas data sets	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5969244	29417587	MO	2	performed laser microdissection	performed laser microdissection	Performed the experiments	Investigation	YES
5969244	29417587	PSB	2	provided human gastric tissue biopsies and pathological assessments	provided human gastric tissue biopsies and pathological assessments	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5969244	29417587	WS	2	provided human gastric tissue biopsies and pathological assessments	provided human gastric tissue biopsies and pathological assessments	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4408048	25905715	WC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408048	25905715	WC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408048	25905715	WC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408048	25905715	XHZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408048	25905715	XHZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408048	25905715	XHZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408048	25905715	XHZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408048	25905715	XW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408048	25905715	XW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408048	25905715	XW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408048	25905715	XW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408048	25905715	YZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5389163	28403819	AF	2	contributed to the design and execution of the experiments detailed|revised the manuscript	contributed to the design and execution of the experiments detailed	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5389163	28403819	AF	2	contributed to the design and execution of the experiments detailed|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5389163	28403819	MAM	2	planned and supervised the study|revised the manuscript	planned and supervised the study	Conceived and designed the experiments	Conceptualization|Supervision	YES
5389163	28403819	MAM	2	planned and supervised the study|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5389163	28403819	MAT	2	contributed to the design and execution of the experiments detailed|provided intellectual input|revised the manuscript	contributed to the design and execution of the experiments detailed	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5389163	28403819	MAT	2	contributed to the design and execution of the experiments detailed|provided intellectual input|revised the manuscript	provided intellectual input	-	-	NO
5389163	28403819	MAT	2	contributed to the design and execution of the experiments detailed|provided intellectual input|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5389163	28403819	MC	2	contributed to the design and execution of the experiments detailed|participated in the construction of the map and qtl mapping|drafted the manuscript	contributed to the design and execution of the experiments detailed	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5389163	28403819	MC	2	contributed to the design and execution of the experiments detailed|participated in the construction of the map and qtl mapping|drafted the manuscript	participated in the construction of the map and qtl mapping	Performed the experiments	Investigation	YES
5389163	28403819	MC	2	contributed to the design and execution of the experiments detailed|participated in the construction of the map and qtl mapping|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5389163	28403819	MCY	2	planned and supervised the study|conducted and evaluated the plant growth|drafted the manuscript|provided intellectual input	planned and supervised the study	Conceived and designed the experiments	Conceptualization|Supervision	YES
5389163	28403819	MCY	2	planned and supervised the study|conducted and evaluated the plant growth|drafted the manuscript|provided intellectual input	conducted and evaluated the plant growth	Performed the experiments	Investigation	YES
5389163	28403819	MCY	2	planned and supervised the study|conducted and evaluated the plant growth|drafted the manuscript|provided intellectual input	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5389163	28403819	MCY	2	planned and supervised the study|conducted and evaluated the plant growth|drafted the manuscript|provided intellectual input	provided intellectual input	-	-	NO
5389163	28403819	RG	2	participated in the construction of the map and qtl mapping|provided intellectual input	participated in the construction of the map and qtl mapping	Performed the experiments	Investigation	YES
5389163	28403819	RG	2	participated in the construction of the map and qtl mapping|provided intellectual input	provided intellectual input	-	-	NO
5577724	28770596	A.O.	2	contributed to conduct of the study, analysis of data and editing/review	contributed to conduct of the study, analysis of data and editing/review	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Review & Editing	YES
5577724	28770596	A.P.	2	contributed to conduct of the study, analysis of data and editing/review	contributed to conduct of the study, analysis of data and editing/review	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Review & Editing	YES
5577724	28770596	B.N.	2	contributed to the conduct of the study and editing/review	contributed to the conduct of the study and editing/review	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5577724	28770596	C.R.C.	2	contributed to the conduct of the study and editing/review	contributed to the conduct of the study and editing/review	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5577724	28770596	D.B.	2	contributed to the conduct of the study and editing/review	contributed to the conduct of the study and editing/review	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5577724	28770596	D.H.	2	contributed to the design of the study, conduct of the study, analysis of the data, drafting of the manuscript and editing/review	contributed to the design of the study, conduct of the study, analysis of the data, drafting of the manuscript and editing/review	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5577724	28770596	D.K.	2	contributed to the design of the study, conduct of the study, analysis of the data, drafting of the manuscript and editing/review	contributed to the design of the study, conduct of the study, analysis of the data, drafting of the manuscript and editing/review	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5577724	28770596	D.M.B.	2	contributed to the conduct of the study and editing/review	contributed to the conduct of the study and editing/review	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5577724	28770596	E.B.	2	contributed to the conduct of the study and editing/review	contributed to the conduct of the study and editing/review	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5577724	28770596	E.D.C.	2	contributed to the design of the study, conduct of the study, analysis of the data, drafting of the manuscript and editing/review	contributed to the design of the study, conduct of the study, analysis of the data, drafting of the manuscript and editing/review	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5577724	28770596	E.H.G.	2	contributed to the conduct of the study and editing/review	contributed to the conduct of the study and editing/review	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5577724	28770596	F.M.	2	contributed to conduct of the study, analysis of data and editing/review	contributed to conduct of the study, analysis of data and editing/review	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Review & Editing	YES
5577724	28770596	J.A.	2	contributed to conduct of the study, analysis of data and editing/review	contributed to conduct of the study, analysis of data and editing/review	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Review & Editing	YES
5577724	28770596	K.S.	2	contributed to the conduct of the study and editing/review	contributed to the conduct of the study and editing/review	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5577724	28770596	L.B.	2	contributed to conduct of the study, analysis of data and editing/review	contributed to conduct of the study, analysis of data and editing/review	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Review & Editing	YES
5577724	28770596	M.L.P.	2	contributed to the design of the study, conduct of the study, analysis of the data, drafting of the manuscript and editing/review	contributed to the design of the study, conduct of the study, analysis of the data, drafting of the manuscript and editing/review	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5577724	28770596	M.R.K.	2	contributed to the design of the study, conduct of the study, analysis of the data, drafting of the manuscript and editing/review	contributed to the design of the study, conduct of the study, analysis of the data, drafting of the manuscript and editing/review	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5577724	28770596	T.C.	2	contributed to the conduct of the study and editing/review	contributed to the conduct of the study and editing/review	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5577724	28770596	T.D.R.	2	contributed to the design of the study, conduct of the study, analysis of the data, drafting of the manuscript and editing/review	contributed to the design of the study, conduct of the study, analysis of the data, drafting of the manuscript and editing/review	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5577724	28770596	V.J.	2	contributed to the design of the study, conduct of the study, analysis of the data, drafting of the manuscript and editing/review	contributed to the design of the study, conduct of the study, analysis of the data, drafting of the manuscript and editing/review	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5601049	28955349	HL	1	Experiments|Manuscript preparation	Experiments	-	-	NO
5601049	28955349	HL	1	Experiments|Manuscript preparation	Manuscript preparation	Wrote the paper	Writing - Original Draft	YES
5601049	28955349	JW	1	Experiments|Data analysis	Experiments	-	-	NO
5601049	28955349	JW	1	Experiments|Data analysis	Data analysis	Analyzed the data	Formal analysis	YES
5601049	28955349	LL	1	Experiments	Experiments	-	-	NO
5601049	28955349	XM	1	Experimental design|Manuscript preparation|Supervision, funding and reagents	Experimental design	Conceived and designed the experiments	Methodology	YES
5601049	28955349	XM	1	Experimental design|Manuscript preparation|Supervision, funding and reagents	Manuscript preparation	Wrote the paper	Writing - Original Draft	YES
5601049	28955349	XM	1	Experimental design|Manuscript preparation|Supervision, funding and reagents	Supervision, funding and reagents	-	Funding acquisition|Supervision	YES
5601049	28955349	ZD	1	Experiments|Manuscript preparation	Experiments	-	-	NO
5601049	28955349	ZD	1	Experiments|Manuscript preparation	Manuscript preparation	Wrote the paper	Writing - Original Draft	YES
5601049	28955349	ZS	1	Experimental design|Data analysis|Manuscript preparation|Supervision, funding and reagents	Experimental design	Conceived and designed the experiments	Methodology	YES
5601049	28955349	ZS	1	Experimental design|Data analysis|Manuscript preparation|Supervision, funding and reagents	Data analysis	Analyzed the data	Formal analysis	YES
5601049	28955349	ZS	1	Experimental design|Data analysis|Manuscript preparation|Supervision, funding and reagents	Manuscript preparation	Wrote the paper	Writing - Original Draft	YES
5601049	28955349	ZS	1	Experimental design|Data analysis|Manuscript preparation|Supervision, funding and reagents	Supervision, funding and reagents	-	Funding acquisition|Supervision	YES
4529930	26273651	George Boutros	2	were responsible for conception and design, data analysis and interpretation, and paper writing and gave final approval of the paper for submission	were responsible for conception and design, data analysis and interpretation, and paper writing and gave final approval of the paper for submission	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
4529930	26273651	George Hilal	2	were responsible for conception and design, data analysis and interpretation, and paper writing and gave final approval of the paper for submission	were responsible for conception and design, data analysis and interpretation, and paper writing and gave final approval of the paper for submission	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
4529930	26273651	Joseph Sidaoui	2	were responsible for conception and design, data analysis and interpretation, and paper writing and gave final approval of the paper for submission	were responsible for conception and design, data analysis and interpretation, and paper writing and gave final approval of the paper for submission	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
4529930	26273651	Layal Wardi	2	were responsible for conception and design, data analysis and interpretation, and paper writing and gave final approval of the paper for submission	were responsible for conception and design, data analysis and interpretation, and paper writing and gave final approval of the paper for submission	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
4529930	26273651	Nada Alaaeddine	2	were responsible for conception and design, data analysis and interpretation, and paper writing and gave final approval of the paper for submission	were responsible for conception and design, data analysis and interpretation, and paper writing and gave final approval of the paper for submission	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
4529930	26273651	Rim Serhal	2	were responsible for conception and design, data analysis and interpretation, and paper writing and gave final approval of the paper for submission	were responsible for conception and design, data analysis and interpretation, and paper writing and gave final approval of the paper for submission	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
4529930	26273651	Salah Ezzeddine	2	were responsible for conception and design, data analysis and interpretation, and paper writing and gave final approval of the paper for submission	were responsible for conception and design, data analysis and interpretation, and paper writing and gave final approval of the paper for submission	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
6220414	30473886	Alok Hemal	2	conceptualised the study|designed the protocol|analysed and interpreted data|approved the final manuscript	conceptualised the study	Conceived and designed the experiments	Conceptualization	YES
6220414	30473886	Alok Hemal	2	conceptualised the study|designed the protocol|analysed and interpreted data|approved the final manuscript	designed the protocol	Conceived and designed the experiments	Methodology	YES
6220414	30473886	Alok Hemal	2	conceptualised the study|designed the protocol|analysed and interpreted data|approved the final manuscript	analysed and interpreted data	Analyzed the data	Formal analysis	YES
6220414	30473886	Alok Hemal	2	conceptualised the study|designed the protocol|analysed and interpreted data|approved the final manuscript	approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6220414	30473886	Rajesh Meena	2	designed the protocol|collected data|analysed and interpreted data|approved the final manuscript	designed the protocol	Conceived and designed the experiments	Methodology	YES
6220414	30473886	Rajesh Meena	2	designed the protocol|collected data|analysed and interpreted data|approved the final manuscript	collected data	Performed the experiments	Investigation	YES
6220414	30473886	Rajesh Meena	2	designed the protocol|collected data|analysed and interpreted data|approved the final manuscript	analysed and interpreted data	Analyzed the data	Formal analysis	YES
6220414	30473886	Rajesh Meena	2	designed the protocol|collected data|analysed and interpreted data|approved the final manuscript	approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6220414	30473886	Shilpa Khanna Arora	2	conceptualised the study|designed the protocol|analysed and interpreted data|approved the final manuscript	conceptualised the study	Conceived and designed the experiments	Conceptualization	YES
6220414	30473886	Shilpa Khanna Arora	2	conceptualised the study|designed the protocol|analysed and interpreted data|approved the final manuscript	designed the protocol	Conceived and designed the experiments	Methodology	YES
6220414	30473886	Shilpa Khanna Arora	2	conceptualised the study|designed the protocol|analysed and interpreted data|approved the final manuscript	analysed and interpreted data	Analyzed the data	Formal analysis	YES
6220414	30473886	Shilpa Khanna Arora	2	conceptualised the study|designed the protocol|analysed and interpreted data|approved the final manuscript	approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
1762319	17183656	AN	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762319	17183656	GK	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762319	17183656	GK	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1762319	17183656	HR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762319	17183656	HR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762319	17183656	HR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762319	17183656	HR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762319	17183656	JL	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762319	17183656	JL	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762319	17183656	LP	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762319	17183656	LP	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762319	17183656	MB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1762319	17183656	MR	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762319	17183656	MR	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762319	17183656	NK	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762319	17183656	NK	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762319	17183656	RH	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762319	17183656	RH	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762319	17183656	RK	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762319	17183656	RK	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762319	17183656	SB	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762319	17183656	SB	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762319	17183656	SK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762319	17183656	SK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762319	17183656	SK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762319	17183656	TU	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762319	17183656	TU	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762319	17183656	VB	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762319	17183656	VB	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4408049	25906061	CMM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408049	25906061	CMM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408049	25906061	CMM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408049	25906061	MD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408049	25906061	MD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408049	25906061	MD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408049	25906061	MD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408049	25906061	PMS	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4408049	25906061	VP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408049	25906061	VP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408049	25906061	VP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408049	25906061	VP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5390369	28407801	DLW	2	helped the experiments	helped the experiments	Performed the experiments	Investigation	YES
5390369	28407801	JJW	2	helped the experiments	helped the experiments	Performed the experiments	Investigation	YES
5390369	28407801	LXG	2	managed the materials in the field	managed the materials in the field	-	-	NO
5390369	28407801	NS	2	helped the experiments	helped the experiments	Performed the experiments	Investigation	YES
5390369	28407801	SW	2	managed the materials in the field	managed the materials in the field	-	-	NO
5390369	28407801	WLF	2	managed the materials in the field	managed the materials in the field	-	-	NO
5390369	28407801	WWY	2	designed the experiments and wrote manuscript	designed the experiments and wrote manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5390369	28407801	XGC	2	helped the experiments	helped the experiments	Performed the experiments	Investigation	YES
5390369	28407801	XGW	2	helped the experiments	helped the experiments	Performed the experiments	Investigation	YES
5390369	28407801	XKL	2	designed the experiments and wrote manuscript	designed the experiments and wrote manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4529931	26273636	Rongfen Gao	2	contributed equally to this work	contributed equally to this work	-	-	NO
4529931	26273636	Wei Sun	2	contributed equally to this work	contributed equally to this work	-	-	NO
5075174	27769311	SM	2	conducted the fieldwork, conceptualised and drafted the paper	conducted the fieldwork, conceptualised and drafted the paper	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
5075174	27769311	SS	2	commented on the various version of the draft and added to the interpretative and ethical-theoretical parts	commented on the various version of the draft and added to the interpretative and ethical-theoretical parts	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5577725	28530044	CF	4	PKL performed the literature search and wrote the draft document subsequently edited and augmented by	PKL performed the literature search and wrote the draft document subsequently edited and augmented by	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5577725	28530044	SF	4	PKL performed the literature search and wrote the draft document subsequently edited and augmented by	PKL performed the literature search and wrote the draft document subsequently edited and augmented by	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
6236663	30515324	Both authors	2	contributed to the conception, design, and execution of this study	contributed to the conception, design, and execution of this study	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
6236663	30515324	Habtamu Mellie Bizuayehu	2	was also involved in the study activities starting from the conception of the idea to the revision of the manuscript throughout the whole process of the study	was also involved in the study activities starting from the conception of the idea to the revision of the manuscript throughout the whole process of the study	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
6236663	30515324	Nurilign Abebe Moges	2	initiate the idea and participated in proposal development, data collection, analysis, manuscript preparation, and revision	initiate the idea and participated in proposal development, data collection, analysis, manuscript preparation, and revision	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
1762320	17183714	BC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762320	17183714	BC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762320	17183714	BC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762320	17183714	CP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1762320	17183714	JW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762320	17183714	JW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762320	17183714	JW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5601060	28955351	DNA	2	to acquire gbs data, analyzed gbs data and produced the first draft of the manuscript|to acquire gbs data and revised critically the manuscript	to acquire gbs data, analyzed gbs data and produced the first draft of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5601060	28955351	DNA	2	to acquire gbs data, analyzed gbs data and produced the first draft of the manuscript|to acquire gbs data and revised critically the manuscript	to acquire gbs data and revised critically the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4408050	25906192	SW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408050	25906192	SW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4408050	25906192	SW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4408050	25906192	SW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408050	25906192	TP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408050	25906192	TP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408050	25906192	TP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408050	25906192	TP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408050	25906192	TP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408050	25906192	YL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408050	25906192	YL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408050	25906192	YL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408050	25906192	YL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408050	25906192	YL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4529932	26273629	Nian-Zhang Zhang	2	contributed equally to this work	contributed equally to this work	-	-	NO
4529932	26273629	Xiao-Xuan Zhang	2	contributed equally to this work	contributed equally to this work	-	-	NO
6304486	30631595	Adino Tesfahun Tsegaye	2	were involved in developing the idea, designing the study, and writing the manuscript	were involved in developing the idea, designing the study, and writing the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
6304486	30631595	Belayneh Kefale	2	were involved in developing the idea, designing the study, and writing the manuscript	were involved in developing the idea, designing the study, and writing the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
6304486	30631595	Boressa Adugna	2	were involved in developing the idea, designing the study, and writing the manuscript	were involved in developing the idea, designing the study, and writing the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
6304486	30631595	Tadesse Melaku	2	were involved in developing the idea, designing the study, and writing the manuscript	were involved in developing the idea, designing the study, and writing the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
6304486	30631595	Yitayih Kefale Gelaw	2	conducted the actual study and the statistical analysis|were involved in developing the idea, designing the study, and writing the manuscript	conducted the actual study and the statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6304486	30631595	Yitayih Kefale Gelaw	2	conducted the actual study and the statistical analysis|were involved in developing the idea, designing the study, and writing the manuscript	were involved in developing the idea, designing the study, and writing the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
5452349	28569221	JG	2	was responsible for study design, and revision and critical review of the manuscript	was responsible for study design, and revision and critical review of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5452349	28569221	KB	2	were responsible for data collection	were responsible for data collection	Performed the experiments	Investigation	YES
5452349	28569221	MD	2	were responsible for data collection	were responsible for data collection	Performed the experiments	Investigation	YES
1762321	17205122	GR	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1762321	17205122	GR	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762321	17205122	SC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762321	17205122	SC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762321	17205122	SC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762321	17205122	SC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5390390	28407733	JRK	PLoS52	generated and characterized dox-inducible and bio-klf9-expressing cell lines, conducted all computer analyses, and conducted all in vitro and in vivo validation studies|wrote the paper	generated and characterized dox-inducible and bio-klf9-expressing cell lines, conducted all computer analyses, and conducted all in vitro and in vivo validation studies	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Validation	YES
5390390	28407733	JRK	PLoS52	generated and characterized dox-inducible and bio-klf9-expressing cell lines, conducted all computer analyses, and conducted all in vitro and in vivo validation studies|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5390390	28407733	RJD	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5577728	28361504	AN	1	Significant intellectual contributions to the article, in alphabetical order	Significant intellectual contributions to the article, in alphabetical order	-	-	NO
5577728	28361504	AW	1	Main article writing	Main article writing	Wrote the paper	-	YES
5577728	28361504	ETC	1	Significant intellectual contributions to the article, in alphabetical order	Significant intellectual contributions to the article, in alphabetical order	-	-	NO
5577728	28361504	LM	1	Significant intellectual contributions to the article, in alphabetical order	Significant intellectual contributions to the article, in alphabetical order	-	-	NO
5577728	28361504	LO	1	Main article writing	Main article writing	Wrote the paper	-	YES
5577728	28361504	MJV	1	Significant intellectual contributions to the article, in alphabetical order	Significant intellectual contributions to the article, in alphabetical order	-	-	NO
5577728	28361504	SB	1	Significant intellectual contributions to the article, in alphabetical order	Significant intellectual contributions to the article, in alphabetical order	-	-	NO
5577728	28361504	TO	1	Significant intellectual contributions to the article, in alphabetical order	Significant intellectual contributions to the article, in alphabetical order	-	-	NO
5601066	28955358	AB	2	conducted genotyping and preparation of dna for sequencing	conducted genotyping and preparation of dna for sequencing	Performed the experiments	Investigation	YES
5601066	28955358	CD	2	conducted genotyping	conducted genotyping	Performed the experiments	Investigation	YES
5601066	28955358	HB	2	contributed to the analysis of historical data, coordinated preparation of variety collections for sequencing and genotyping and edited the manuscript	contributed to the analysis of historical data, coordinated preparation of variety collections for sequencing and genotyping and edited the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Project administration|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5601066	28955358	JM	2	prepared libraries for sequencing	prepared libraries for sequencing	Performed the experiments	Investigation	YES
5601066	28955358	JR	2	designed the experimental approach, coordinated the research and contributed to manuscript preparation	designed the experimental approach, coordinated the research and contributed to manuscript preparation	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft	YES
5601066	28955358	LR	2	contributed to the experimental design and edited the manuscript	contributed to the experimental design and edited the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
5601066	28955358	MB	2	advised on experimental design, conducted bioinformatics analysis and contributed to manuscript preparation	advised on experimental design, conducted bioinformatics analysis and contributed to manuscript preparation	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5601066	28955358	ML	2	contributed to experimental design, analyzed and interpreted data, and wrote the manuscript	contributed to experimental design, analyzed and interpreted data, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
5601066	28955358	PH	2	advised on experimental design, coordinated exome capture and sequencing, and contributed to manuscript preparation	advised on experimental design, coordinated exome capture and sequencing, and contributed to manuscript preparation	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Project administration|Writing - Original Draft	YES
5601066	28955358	WT	2	contributed to the experimental design, analyzed historical malting quality data and contributed to manuscript preparation	contributed to the experimental design, analyzed historical malting quality data and contributed to manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
4529933	26273654	Zetao Liao	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
4529933	26273654	Zhiming Lin	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
4408052	25906393	AG-N	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4408052	25906393	BJK	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4408052	25906393	BJK	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4408052	25906393	BS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408052	25906393	BS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408052	25906393	BS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408052	25906393	BS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408052	25906393	CMW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408052	25906393	CMW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4408052	25906393	CMW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408052	25906393	CRS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408052	25906393	CRS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408052	25906393	CRS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408052	25906393	CRS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408052	25906393	ELB	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4408052	25906393	ELB	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4408052	25906393	JRB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408052	25906393	JRB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408052	25906393	WKA	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4408052	25906393	WKA	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
6041155	29492969	AJS	2	contributed to tma/data collection, data generation and/or data management	contributed to tma/data collection, data generation and/or data management	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Investigation|Resources	YES
6041155	29492969	All authors	2	contributed to manuscript development and writing and gave final approval for its submission	contributed to manuscript development and writing and gave final approval for its submission	Wrote the paper	Writing - Original Draft	YES
6041155	29492969	DFE	2	contributed to tma/data collection, data generation and/or data management	contributed to tma/data collection, data generation and/or data management	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Investigation|Resources	YES
6041155	29492969	FD	2	carried out centralized laboratory work and automated scoring on ki67, respectively	carried out centralized laboratory work and automated scoring on ki67, respectively	Performed the experiments	Investigation	YES
6041155	29492969	HRA	2	were members of the initial writing group for the manuscript	were members of the initial writing group for the manuscript	Wrote the paper	Writing - Original Draft	YES
6041155	29492969	JCC	2	were members of the initial writing group for the manuscript	were members of the initial writing group for the manuscript	Wrote the paper	Writing - Original Draft	YES
6041155	29492969	MA	2	conceived and carried out the analysis|carried out centralized laboratory work and automated scoring on ki67, respectively|were members of the initial writing group for the manuscript	conceived and carried out the analysis	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
6041155	29492969	MA	2	conceived and carried out the analysis|carried out centralized laboratory work and automated scoring on ki67, respectively|were members of the initial writing group for the manuscript	carried out centralized laboratory work and automated scoring on ki67, respectively	Performed the experiments	Investigation	YES
6041155	29492969	MA	2	conceived and carried out the analysis|carried out centralized laboratory work and automated scoring on ki67, respectively|were members of the initial writing group for the manuscript	were members of the initial writing group for the manuscript	Wrote the paper	Writing - Original Draft	YES
6041155	29492969	MES	2	were members of the initial writing group for the manuscript	were members of the initial writing group for the manuscript	Wrote the paper	Writing - Original Draft	YES
6041155	29492969	MG-C	2	conceived and carried out the analysis|supervised the work|contributed to tma/data collection, data generation and/or data management	conceived and carried out the analysis	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
6041155	29492969	MG-C	2	conceived and carried out the analysis|supervised the work|contributed to tma/data collection, data generation and/or data management	supervised the work	-	Supervision	YES
6041155	29492969	MG-C	2	conceived and carried out the analysis|supervised the work|contributed to tma/data collection, data generation and/or data management	contributed to tma/data collection, data generation and/or data management	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Investigation|Resources	YES
6041155	29492969	MGC	2	were members of the initial writing group for the manuscript	were members of the initial writing group for the manuscript	Wrote the paper	Writing - Original Draft	YES
6041155	29492969	MJ	2	contributed to tma/data collection, data generation and/or data management	contributed to tma/data collection, data generation and/or data management	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Investigation|Resources	YES
6041155	29492969	MJS	2	contributed to tma/data collection, data generation and/or data management	contributed to tma/data collection, data generation and/or data management	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Investigation|Resources	YES
6041155	29492969	MKB	2	contributed to tma/data collection, data generation and/or data management	contributed to tma/data collection, data generation and/or data management	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Investigation|Resources	YES
6041155	29492969	MKS	2	were members of the initial writing group for the manuscript|contributed to tma/data collection, data generation and/or data management	were members of the initial writing group for the manuscript	Wrote the paper	Writing - Original Draft	YES
6041155	29492969	MKS	2	were members of the initial writing group for the manuscript|contributed to tma/data collection, data generation and/or data management	contributed to tma/data collection, data generation and/or data management	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Investigation|Resources	YES
6041155	29492969	NC	2	were members of the initial writing group for the manuscript	were members of the initial writing group for the manuscript	Wrote the paper	Writing - Original Draft	YES
6041155	29492969	PC	2	performed ki67 data management	performed ki67 data management	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
6041155	29492969	PDP	2	were members of the initial writing group for the manuscript|contributed to tma/data collection, data generation and/or data management	were members of the initial writing group for the manuscript	Wrote the paper	Writing - Original Draft	YES
6041155	29492969	PDP	2	were members of the initial writing group for the manuscript|contributed to tma/data collection, data generation and/or data management	contributed to tma/data collection, data generation and/or data management	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Investigation|Resources	YES
6041155	29492969	QW	2	contributed to tma/data collection, data generation and/or data management	contributed to tma/data collection, data generation and/or data management	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Investigation|Resources	YES
6041155	29492969	RK	2	contributed to tma/data collection, data generation and/or data management	contributed to tma/data collection, data generation and/or data management	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Investigation|Resources	YES
1762322	17183660	CF	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762322	17183660	CF	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762322	17183660	IS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762322	17183660	IS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762322	17183660	IS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762322	17183660	JS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1762322	17183660	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762322	17183660	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762322	17183660	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762322	17183660	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762322	17183660	NM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762322	17183660	PP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1762322	17183660	PP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
6334359	30719348	Dessie Abebaw	2	revised the proposal and checked the data analysis	revised the proposal and checked the data analysis	Analyzed the data|Wrote the paper	Data curation|Formal analysis|Writing - Review & Editing	YES
6334359	30719348	Helina Abebe	2	developed the proposal, supervised the data collection, analyzed the data, and wrote the draft manuscript	developed the proposal, supervised the data collection, analyzed the data, and wrote the draft manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Supervision|Writing - Original Draft	YES
6334359	30719348	Melkamu Agidew	2	revised the proposal and checked the data analysis	revised the proposal and checked the data analysis	Analyzed the data|Wrote the paper	Data curation|Formal analysis|Writing - Review & Editing	YES
6334359	30719348	Shegaye Shumet	2	revised the proposal, checked the data analysis, and revised and approved the manuscript	revised the proposal, checked the data analysis, and revised and approved the manuscript	Analyzed the data|Wrote the paper	Data curation|Formal analysis|Writing - Review & Editing	YES
6334359	30719348	Zebiba Nassir	2	revised the proposal and assisted in the data analysis	revised the proposal and assisted in the data analysis	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5390406	28407753	CU	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
5390406	28407753	CU	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5390406	28407753	IH	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5390406	28407753	JI	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
5390406	28407753	JI	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5390406	28407753	JLL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5390406	28407753	KH	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5390406	28407753	SD	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5390406	28407753	SRR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5390406	28407753	SRR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
5390406	28407753	SRR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
5390406	28407753	SRR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5390406	28407753	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5390406	28407753	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
5390406	28407753	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
5390406	28407753	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5601067	28955366	CB	2	edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5601067	28955366	G-LZ	2	designed the experimental strategy, analyzed the data, and drafted the manuscript	designed the experimental strategy, analyzed the data, and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5601067	28955366	J-HW	2	designed the experimental strategy, analyzed the data, and drafted the manuscript	designed the experimental strategy, analyzed the data, and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5601067	28955366	LW	2	conducted the transpirational water loss assay	conducted the transpirational water loss assay	Performed the experiments	Investigation	YES
5601067	28955366	QF	2	measured the water content	measured the water content	Performed the experiments	Investigation	YES
5601067	28955366	W-DF	2	edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5601067	28955366	Z-NZ	2	carried out the chlorophyll content assay	carried out the chlorophyll content assay	Performed the experiments	Investigation	YES
5601067	28955366	ZS	2	measured and calculated the biomass	measured and calculated the biomass	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5574124	28841899	CFC	2	provided additional context specific information	provided additional context specific information	Wrote the paper	Writing - Original Draft	YES
5574124	28841899	CKW	2	searched relevant literature, scrutinized all relevant information and draft the manuscript|provided additional context specific information	searched relevant literature, scrutinized all relevant information and draft the manuscript	Wrote the paper	Formal analysis|Writing - Original Draft	YES
5574124	28841899	CKW	2	searched relevant literature, scrutinized all relevant information and draft the manuscript|provided additional context specific information	provided additional context specific information	Wrote the paper	Writing - Original Draft	YES
5574124	28841899	EIMK	2	provided additional context specific information	provided additional context specific information	Wrote the paper	Writing - Original Draft	YES
5574124	28841899	ET	2	generated the idea, led and constructed the framework|searched relevant literature, scrutinized all relevant information and draft the manuscript|provided additional context specific information	generated the idea, led and constructed the framework	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5574124	28841899	ET	2	generated the idea, led and constructed the framework|searched relevant literature, scrutinized all relevant information and draft the manuscript|provided additional context specific information	searched relevant literature, scrutinized all relevant information and draft the manuscript	Wrote the paper	Formal analysis|Writing - Original Draft	YES
5574124	28841899	ET	2	generated the idea, led and constructed the framework|searched relevant literature, scrutinized all relevant information and draft the manuscript|provided additional context specific information	provided additional context specific information	Wrote the paper	Writing - Original Draft	YES
5574124	28841899	GM	2	searched relevant literature, scrutinized all relevant information and draft the manuscript|provided additional context specific information	searched relevant literature, scrutinized all relevant information and draft the manuscript	Wrote the paper	Formal analysis|Writing - Original Draft	YES
5574124	28841899	GM	2	searched relevant literature, scrutinized all relevant information and draft the manuscript|provided additional context specific information	provided additional context specific information	Wrote the paper	Writing - Original Draft	YES
5574124	28841899	OAO	2	provided additional context specific information	provided additional context specific information	Wrote the paper	Writing - Original Draft	YES
4408053	25905794	AE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408053	25905794	AE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4408053	25905794	AE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4408053	25905794	EF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408053	25905794	EF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408053	25905794	EF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408053	25905794	EF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408053	25905794	JPF	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4408053	25905794	JPF	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4408053	25905794	LN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408053	25905794	LN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4408053	25905794	LN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4408053	25905794	VJJM	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408053	25905794	VJJM	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762323	17183696	FT	PLoS5	Performed all chemical analyses	Performed all chemical analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
1762323	17183696	TR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762323	17183696	TR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762323	17183696	TR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762323	17183696	TV	PLoS5	Analyzed the data|Collected all tissue samples and literature data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762323	17183696	TV	PLoS5	Analyzed the data|Collected all tissue samples and literature data	Collected all tissue samples and literature data	Performed the experiments	Formal analysis|Investigation	YES
1762323	17183696	WA	PLoS5	Contributed reagents/materials/analysis tools|Contributed to the writing of the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762323	17183696	WA	PLoS5	Contributed reagents/materials/analysis tools|Contributed to the writing of the paper	Contributed to the writing of the paper	Wrote the paper	Writing - Original Draft	YES
4408054	25905636	NY	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408054	25905636	NY	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408054	25905636	NY	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408054	25905636	TC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408054	25905636	TC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408054	25905636	TC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408054	25905636	TC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408054	25905636	TC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408054	25905636	TL	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408054	25905636	TL	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5390407	28407798	CG	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5390407	28407798	JCV	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5390407	28407798	KN	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5390407	28407798	NK	PLoS52	designed research|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
5390407	28407798	NK	PLoS52	designed research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5390407	28407798	SY	PLoS52	designed research|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
5390407	28407798	SY	PLoS52	designed research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5390407	28407798	VS	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5390407	28407798	WL	PLoS52	designed research|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
5390407	28407798	WL	PLoS52	designed research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5390407	28407798	WWG	PLoS52	designed research|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
5390407	28407798	WWG	PLoS52	designed research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762324	17183730	AD	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762324	17183730	AD	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762324	17183730	AR	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762324	17183730	CA	PLoS5	Conceived and designed the experiments|Clinical care of patients	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762324	17183730	CA	PLoS5	Conceived and designed the experiments|Clinical care of patients	Clinical care of patients	Performed the experiments	Investigation	YES
1762324	17183730	CP	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762324	17183730	EB	PLoS5	Clinical care of patients	Clinical care of patients	Performed the experiments	Investigation	YES
1762324	17183730	ER	PLoS5	Clinical care of patients	Clinical care of patients	Performed the experiments	Investigation	YES
1762324	17183730	PV	PLoS5	Clinical care of patients	Clinical care of patients	Performed the experiments	Investigation	YES
1762324	17183730	TR	PLoS5	Clinical care of patients	Clinical care of patients	Performed the experiments	Investigation	YES
1762324	17183730	TV	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5574152	28841897	All authors	2	contributed to the literature review|contributed to discussions about information sheet design, including reviewing and selecting the final design	contributed to the literature review	-	Formal analysis	YES
5574152	28841897	All authors	2	contributed to the literature review|contributed to discussions about information sheet design, including reviewing and selecting the final design	contributed to discussions about information sheet design, including reviewing and selecting the final design	Conceived and designed the experiments	-	YES
5574152	28841897	JS	2	conducted the focus groups and analysis of focus group transcripts|conducted 1|reviewed 6 transcripts each|reviewed and approved the final manuscript	conducted the focus groups and analysis of focus group transcripts	Performed the experiments	Investigation	YES
5574152	28841897	JS	2	conducted the focus groups and analysis of focus group transcripts|conducted 1|reviewed 6 transcripts each|reviewed and approved the final manuscript	conducted 1	Performed the experiments	Investigation	YES
5574152	28841897	JS	2	conducted the focus groups and analysis of focus group transcripts|conducted 1|reviewed 6 transcripts each|reviewed and approved the final manuscript	reviewed 6 transcripts each	-	-	NO
5574152	28841897	JS	2	conducted the focus groups and analysis of focus group transcripts|conducted 1|reviewed 6 transcripts each|reviewed and approved the final manuscript	reviewed and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5574152	28841897	KA	2	conducted the literature search|wrote the manuscript with input from the other authors	conducted the literature search	Performed the experiments	Formal analysis|Investigation	YES
5574152	28841897	KA	2	conducted the literature search|wrote the manuscript with input from the other authors	wrote the manuscript with input from the other authors	Wrote the paper	Writing - Original Draft	YES
5574152	28841897	RJ	2	conducted the focus groups and analysis of focus group transcripts|reviewed 6 transcripts each	conducted the focus groups and analysis of focus group transcripts	Performed the experiments	Investigation	YES
5574152	28841897	RJ	2	conducted the focus groups and analysis of focus group transcripts|reviewed 6 transcripts each	reviewed 6 transcripts each	-	-	NO
5574152	28841897	VAC	2	conducted the focus groups and analysis of focus group transcripts|reviewed 6 transcripts each|reviewed and approved the final manuscript	conducted the focus groups and analysis of focus group transcripts	Performed the experiments	Investigation	YES
5574152	28841897	VAC	2	conducted the focus groups and analysis of focus group transcripts|reviewed 6 transcripts each|reviewed and approved the final manuscript	reviewed 6 transcripts each	-	-	NO
5574152	28841897	VAC	2	conducted the focus groups and analysis of focus group transcripts|reviewed 6 transcripts each|reviewed and approved the final manuscript	reviewed and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5601070	28955359	CE-E	PLoS52	carried out the experimental work|contributed to experimental design and data analysis	carried out the experimental work	Performed the experiments	Investigation	YES
5601070	28955359	CE-E	PLoS52	carried out the experimental work|contributed to experimental design and data analysis	contributed to experimental design and data analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Methodology|Resources	YES
5601070	28955359	GL-T	PLoS52	carried out the experimental work|contributed to experimental design and data analysis	carried out the experimental work	Performed the experiments	Investigation	YES
5601070	28955359	GL-T	PLoS52	carried out the experimental work|contributed to experimental design and data analysis	contributed to experimental design and data analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Methodology|Resources	YES
5601070	28955359	LR	PLoS52	contributed to experimental design and data analysis|wrote the paper	contributed to experimental design and data analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Methodology|Resources	YES
5601070	28955359	LR	PLoS52	contributed to experimental design and data analysis|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5601070	28955359	SB	PLoS52	carried out the experimental work|contributed to experimental design and data analysis|wrote the paper	carried out the experimental work	Performed the experiments	Investigation	YES
5601070	28955359	SB	PLoS52	carried out the experimental work|contributed to experimental design and data analysis|wrote the paper	contributed to experimental design and data analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Methodology|Resources	YES
5601070	28955359	SB	PLoS52	carried out the experimental work|contributed to experimental design and data analysis|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5601070	28955359	XJ	PLoS52	carried out the experimental work|contributed to experimental design and data analysis	carried out the experimental work	Performed the experiments	Investigation	YES
5601070	28955359	XJ	PLoS52	carried out the experimental work|contributed to experimental design and data analysis	contributed to experimental design and data analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Methodology|Resources	YES
4408055	25905787	HY	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408055	25905787	HY	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408055	25905787	HY	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408055	25905787	LZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408055	25905787	LZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408055	25905787	LZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408055	25905787	LZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408055	25905787	SYL	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408055	25905787	SYL	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4408055	25905787	TZ	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408055	25905787	TZ	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408055	25905787	TZ	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408055	25905787	WHD	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4408055	25905787	WHD	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408055	25905787	WX	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4408055	25905787	WX	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408055	25905787	XSX	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408055	25905787	XSX	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408055	25905787	YNC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408055	25905787	YNC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408055	25905787	YNC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5390434	28407751	CJS	2	designed the experiment, provided reagents, materials and analysis tools, and revised the manuscript|directed and participated in the animal experiments in university of delaware	designed the experiment, provided reagents, materials and analysis tools, and revised the manuscript	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Methodology|Resources|Writing - Review & Editing	YES
5390434	28407751	CJS	2	designed the experiment, provided reagents, materials and analysis tools, and revised the manuscript|directed and participated in the animal experiments in university of delaware	directed and participated in the animal experiments in university of delaware	Performed the experiments	Investigation|Supervision	YES
5390434	28407751	JZ	2	analyzed rna seq data, did biomark assay validation and wrote the manuscript	analyzed rna seq data, did biomark assay validation and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Validation|Writing - Original Draft	YES
5390434	28407751	SJL	2	designed the experiment, provided reagents, materials and analysis tools, and revised the manuscript	designed the experiment, provided reagents, materials and analysis tools, and revised the manuscript	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Methodology|Resources|Writing - Review & Editing	YES
5576279	28851402	DS	2	contributed equally to the paper concept and writing	contributed equally to the paper concept and writing	Conceived and designed the experiments|Wrote the paper	Conceptualization	YES
5576279	28851402	JT	2	contributed equally to the paper concept and writing	contributed equally to the paper concept and writing	Conceived and designed the experiments|Wrote the paper	Conceptualization	YES
5601397	28955365	BL	2	helped with the data analysis of the pacbio and sanger sequencing	helped with the data analysis of the pacbio and sanger sequencing	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5601397	28955365	JC	2	provided the herbal samples and were responsible for determining the extent of contamination in them	provided the herbal samples and were responsible for determining the extent of contamination in them	Contributed reagents/materials/analysis tools	Resources	YES
5601397	28955365	JL	2	carried out the microscopic and hplc assays, and also analyzed the data	carried out the microscopic and hplc assays, and also analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5601397	28955365	JX	2	conceived the study, participated in its design and coordination, and helped to draft the manuscript	conceived the study, participated in its design and coordination, and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
5601397	28955365	PZ	2	contributed to all the researches activities associated with this work	contributed to all the researches activities associated with this work	Performed the experiments	Investigation	YES
5601397	28955365	SC	2	conceived the study, participated in its design and coordination, and helped to draft the manuscript	conceived the study, participated in its design and coordination, and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
5601397	28955365	XL	2	carried out the microscopic and hplc assays, and also analyzed the data	carried out the microscopic and hplc assays, and also analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5601397	28955365	XZ	2	contributed to all the researches activities associated with this work|was responsible for writing the manuscript	contributed to all the researches activities associated with this work	Performed the experiments	Investigation	YES
5601397	28955365	XZ	2	contributed to all the researches activities associated with this work|was responsible for writing the manuscript	was responsible for writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5601397	28955365	YS	2	helped with the data analysis of the pacbio and sanger sequencing	helped with the data analysis of the pacbio and sanger sequencing	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5601397	28955365	ZL	2	provided the herbal samples and were responsible for determining the extent of contamination in them	provided the herbal samples and were responsible for determining the extent of contamination in them	Contributed reagents/materials/analysis tools	Resources	YES
1762325	17183641	FH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762325	17183641	FH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762325	17183641	FH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762325	17183641	HC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1762325	17183641	KF	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762325	17183641	KF	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762325	17183641	MN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762325	17183641	MN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762325	17183641	MN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762325	17183641	MN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762325	17183641	MN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762325	17183641	MO	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762325	17183641	MO	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762325	17183641	SY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762325	17183641	SY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762325	17183641	SY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762325	17183641	TA	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762325	17183641	TA	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762325	17183641	TT	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1762325	17183641	UK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762325	17183641	UK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762325	17183641	UK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762325	17183641	UK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408056	25906284	AJM	PLoS5	Analyzed the data|Wrote the paper|Data acquisition	Analyzed the data	Analyzed the data	Formal analysis	YES
4408056	25906284	AJM	PLoS5	Analyzed the data|Wrote the paper|Data acquisition	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408056	25906284	AJM	PLoS5	Analyzed the data|Wrote the paper|Data acquisition	Data acquisition	Performed the experiments	Investigation	YES
4408056	25906284	CPK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Data acquisition	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408056	25906284	CPK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Data acquisition	Analyzed the data	Analyzed the data	Formal analysis	YES
4408056	25906284	CPK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Data acquisition	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408056	25906284	CPK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Data acquisition	Data acquisition	Performed the experiments	Investigation	YES
4408056	25906284	DAL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Data acquisition	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408056	25906284	DAL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Data acquisition	Analyzed the data	Analyzed the data	Formal analysis	YES
4408056	25906284	DAL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Data acquisition	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408056	25906284	DAL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Data acquisition	Data acquisition	Performed the experiments	Investigation	YES
4408056	25906284	DNS	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408056	25906284	DNS	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408056	25906284	KS	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408056	25906284	KS	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408056	25906284	KWG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Data acquisition	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408056	25906284	KWG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Data acquisition	Analyzed the data	Analyzed the data	Formal analysis	YES
4408056	25906284	KWG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Data acquisition	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408056	25906284	KWG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Data acquisition	Data acquisition	Performed the experiments	Investigation	YES
4408056	25906284	LK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Data acquisition	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408056	25906284	LK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Data acquisition	Analyzed the data	Analyzed the data	Formal analysis	YES
4408056	25906284	LK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Data acquisition	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408056	25906284	LK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Data acquisition	Data acquisition	Performed the experiments	Investigation	YES
4408056	25906284	MH	PLoS5	Analyzed the data|Wrote the paper|Data acquisition	Analyzed the data	Analyzed the data	Formal analysis	YES
4408056	25906284	MH	PLoS5	Analyzed the data|Wrote the paper|Data acquisition	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408056	25906284	MH	PLoS5	Analyzed the data|Wrote the paper|Data acquisition	Data acquisition	Performed the experiments	Investigation	YES
4408056	25906284	SS	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408056	25906284	SS	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408056	25906284	SWF	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408056	25906284	SWF	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408056	25906284	XN	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Data acquisition	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408056	25906284	XN	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Data acquisition	Analyzed the data	Analyzed the data	Formal analysis	YES
4408056	25906284	XN	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Data acquisition	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408056	25906284	XN	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Data acquisition	Data acquisition	Performed the experiments	Investigation	YES
6441518	31007955	Eleni Tesfaye	2	was involved in supervision of field work, the revision of the research design, statistical analysis, and preparing the manuscript	was involved in supervision of field work, the revision of the research design, statistical analysis, and preparing the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
6441518	31007955	Kaleab Tesfaye	2	contributed to the revision of the research design, statistical analysis, and preparing the manuscript	contributed to the revision of the research design, statistical analysis, and preparing the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
6441518	31007955	Mekibib Kassa	2	was involved in data analysis, preparation, and revision of the manuscript for publication	was involved in data analysis, preparation, and revision of the manuscript for publication	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
6441518	31007955	Mohammed Seid Ali	2	theorized the research problem, designed the study, conducted field work, analyzed the data, and revised the manuscript	theorized the research problem, designed the study, conducted field work, analyzed the data, and revised the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Review & Editing	YES
1762326	17183677	GE	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762326	17183677	GE	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762326	17183677	MN	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762326	17183677	MN	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762326	17183677	MN	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762326	17183677	RW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762326	17183677	RW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762326	17183677	RW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5392906	28412928	BM	2	conceived the study and coordinated the research	conceived the study and coordinated the research	Conceived and designed the experiments	Conceptualization|Project administration	YES
5392906	28412928	JF	2	performed the qpcr experiments and analysed the corresponding results	performed the qpcr experiments and analysed the corresponding results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5392906	28412928	LP	2	performed data mining, data analysis and wrote the manuscript	performed data mining, data analysis and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5392906	28412928	MD	2	conceived the study, coordinated the research and wrote the manuscript	conceived the study, coordinated the research and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Project administration|Writing - Original Draft	YES
5392906	28412928	NLF	2	conceived the study, coordinated the research and wrote the manuscript	conceived the study, coordinated the research and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Project administration|Writing - Original Draft	YES
5601402	28955356	AT	2	designed the study including experimental design|carried out the physiological studies|analyzed the data and drafted the manuscript	designed the study including experimental design	Conceived and designed the experiments	Methodology	YES
5601402	28955356	AT	2	designed the study including experimental design|carried out the physiological studies|analyzed the data and drafted the manuscript	carried out the physiological studies	Performed the experiments	Investigation	YES
5601402	28955356	AT	2	designed the study including experimental design|carried out the physiological studies|analyzed the data and drafted the manuscript	analyzed the data and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5601402	28955356	AZ	2	carried out the physiological studies	carried out the physiological studies	Performed the experiments	Investigation	YES
5601402	28955356	CG	2	contributed to revising the draft	contributed to revising the draft	Wrote the paper	Writing - Original Draft	YES
5601402	28955356	CL	2	contributed to revising the draft	contributed to revising the draft	Wrote the paper	Writing - Original Draft	YES
5601402	28955356	DM	2	contributed reagents, materials, and analysis tools	contributed reagents, materials, and analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5601402	28955356	DS	2	contributed reagents, materials, and analysis tools	contributed reagents, materials, and analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5601402	28955356	KP	2	designed the study including experimental design|contributed to revising the draft	designed the study including experimental design	Conceived and designed the experiments	Methodology	YES
5601402	28955356	KP	2	designed the study including experimental design|contributed to revising the draft	contributed to revising the draft	Wrote the paper	Writing - Original Draft	YES
5601402	28955356	LZ	2	contributed to revising the draft	contributed to revising the draft	Wrote the paper	Writing - Original Draft	YES
5601402	28955356	OO	2	carried out the physiological studies	carried out the physiological studies	Performed the experiments	Investigation	YES
5601402	28955356	QX	2	contributed reagents, materials, and analysis tools	contributed reagents, materials, and analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5601402	28955356	WC	2	carried out the physiological studies	carried out the physiological studies	Performed the experiments	Investigation	YES
5601402	28955356	XS	2	contributed to revising the draft	contributed to revising the draft	Wrote the paper	Writing - Original Draft	YES
5601402	28955356	XW	2	contributed reagents, materials, and analysis tools	contributed reagents, materials, and analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5601402	28955356	ZL	2	carried out the physiological studies	carried out the physiological studies	Performed the experiments	Investigation	YES
4737313	26505992	A.A.S.	1	Conception and design of the study	Conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4737313	26505992	C.L.M.	1	Conception and design of the study	Conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4737313	26505992	F.N.R.-C.	1	Conception and design of the study	Conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4737313	26505992	V.C.	1	Conception and design of the study	Conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4737313	26505992	Y.K.	1	Conception and design of the study	Conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408057	25905799	ER	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4408057	25905799	HS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408057	25905799	HS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408057	25905799	JST	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4408057	25905799	KS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4408057	25905799	MN	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408057	25905799	MR	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408057	25905799	RME	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4408057	25905799	SG	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408057	25905799	SH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4408057	25905799	WB	PLoS5	Conceived and designed the experiments|Wrote the paper|Critical revisions of the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408057	25905799	WB	PLoS5	Conceived and designed the experiments|Wrote the paper|Critical revisions of the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408057	25905799	WB	PLoS5	Conceived and designed the experiments|Wrote the paper|Critical revisions of the manuscript	Critical revisions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4529939	26273628	Pingping Zhang	2	contributed equally	contributed equally	-	-	NO
4529939	26273628	Qiuxia Li	2	contributed equally	contributed equally	-	-	NO
1762327	17183681	KI	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Wrote the paper|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762327	17183681	KI	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Wrote the paper|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762327	17183681	KI	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Wrote the paper|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762327	17183681	KI	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Wrote the paper|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762327	17183681	KI	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Wrote the paper|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762327	17183681	KI	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Wrote the paper|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762327	17183681	KI	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Wrote the paper|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762327	17183681	KI	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Wrote the paper|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762327	17183681	PM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1762327	17183681	PM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762327	17183681	SG	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762327	17183681	SG	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762327	17183681	SI	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762327	17183681	SI	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762327	17183681	SI	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762327	17183681	SP	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762327	17183681	SP	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762327	17183681	ST	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762327	17183681	ST	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762327	17183681	TN	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762327	17183681	TN	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762327	17183681	TS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762327	17183681	TS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762327	17183681	TS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762327	17183681	TS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762327	17183681	YS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762327	17183681	YS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5601409	28955357	AB	2	designed the experiments, performed the assemblies, comparative analysis and experiments, and wrote the manuscript	designed the experiments, performed the assemblies, comparative analysis and experiments, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5601409	28955357	DN	2	conceived the work, supervised, coordinated all activities and provided critical review to the manuscript	conceived the work, supervised, coordinated all activities and provided critical review to the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Project administration|Supervision|Writing - Review & Editing	YES
5601409	28955357	JH-T	2	supported the bioinformatics work for the comparative analysis and reviewed the manuscript	supported the bioinformatics work for the comparative analysis and reviewed the manuscript	Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5392922	28415971	CF	2	performed the infection and rna seq|wrote the manuscript	performed the infection and rna seq	Performed the experiments	Investigation	YES
5392922	28415971	CF	2	performed the infection and rna seq|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5392922	28415971	DW	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5392922	28415971	HJ	2	performed the infection and rna seq|performed the molecular biology experiments	performed the infection and rna seq	Performed the experiments	Investigation	YES
5392922	28415971	HJ	2	performed the infection and rna seq|performed the molecular biology experiments	performed the molecular biology experiments	Performed the experiments	Investigation	YES
5392922	28415971	KC	2	performed the infection and rna seq|performed the molecular biology experiments|performed the computational analysis|wrote the manuscript	performed the infection and rna seq	Performed the experiments	Investigation	YES
5392922	28415971	KC	2	performed the infection and rna seq|performed the molecular biology experiments|performed the computational analysis|wrote the manuscript	performed the molecular biology experiments	Performed the experiments	Investigation	YES
5392922	28415971	KC	2	performed the infection and rna seq|performed the molecular biology experiments|performed the computational analysis|wrote the manuscript	performed the computational analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5392922	28415971	KC	2	performed the infection and rna seq|performed the molecular biology experiments|performed the computational analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5392922	28415971	YJ	2	performed the infection and rna seq	performed the infection and rna seq	Performed the experiments	Investigation	YES
1762328	17183631	AR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762328	17183631	AR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762328	17183631	AR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762328	17183631	AS	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762328	17183631	AS	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762328	17183631	LB	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762328	17183631	LB	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762328	17183631	MA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762328	17183631	MA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762328	17183631	MA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762328	17183631	MA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408058	25905623	FD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408058	25905623	FD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408058	25905623	FD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408058	25905623	FD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408058	25905623	FD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408058	25905623	LHS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408058	25905623	LHS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408058	25905623	LHS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408058	25905623	LHS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408058	25905623	LHS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408058	25905623	MS	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408058	25905623	MS	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4738442	26580862	B.A.O.	2	helped structure and edit the review	helped structure and edit the review	-	-	NO
4738442	26580862	C.D.M.	2	proposed the concept for the review and contributed to the writing	proposed the concept for the review and contributed to the writing	Conceived and designed the experiments|Wrote the paper	Conceptualization	YES
4738442	26580862	D.-S.W.	2	helped structure and edit the review	helped structure and edit the review	-	-	NO
4738442	26580862	I.L.	2	wrote the review and created the figures	wrote the review and created the figures	Wrote the paper	Visualization|Writing - Original Draft	YES
4738442	26580862	P.D.W.	2	helped structure and edit the review	helped structure and edit the review	-	-	NO
4738442	26580862	S.A.	2	helped structure and edit the review	helped structure and edit the review	-	-	NO
5843813	29564387	AJ	2	developed the presentation on which this manuscript is based, and were involved in the drafting and final approval of the manuscript	developed the presentation on which this manuscript is based, and were involved in the drafting and final approval of the manuscript	Wrote the paper	Writing - Original Draft	YES
5843813	29564387	AM	2	developed the presentation on which this manuscript is based, and were involved in the drafting and final approval of the manuscript	developed the presentation on which this manuscript is based, and were involved in the drafting and final approval of the manuscript	Wrote the paper	Writing - Original Draft	YES
5843813	29564387	AS	2	developed the presentation on which this manuscript is based, and were involved in the drafting and final approval of the manuscript	developed the presentation on which this manuscript is based, and were involved in the drafting and final approval of the manuscript	Wrote the paper	Writing - Original Draft	YES
5843813	29564387	NK	2	developed the presentation on which this manuscript is based, and were involved in the drafting and final approval of the manuscript	developed the presentation on which this manuscript is based, and were involved in the drafting and final approval of the manuscript	Wrote the paper	Writing - Original Draft	YES
5662100	29082852	EJC	2	is responsible for all intellectual contributions in writing and researching of this manuscript and has approved the final manuscript|agrees to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	is responsible for all intellectual contributions in writing and researching of this manuscript and has approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5662100	29082852	EJC	2	is responsible for all intellectual contributions in writing and researching of this manuscript and has approved the final manuscript|agrees to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	agrees to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	-	-	NO
5601411	28955368	KS	2	contributed to the writing and refining of the manuscript	contributed to the writing and refining of the manuscript	Wrote the paper	Writing - Original Draft	YES
5601411	28955368	PB	2	contributed to the writing and refining of the manuscript	contributed to the writing and refining of the manuscript	Wrote the paper	Writing - Original Draft	YES
5601411	28955368	SA	2	contributed to the writing and refining of the manuscript	contributed to the writing and refining of the manuscript	Wrote the paper	Writing - Original Draft	YES
5601411	28955368	SP	2	conceived the idea and wrote the first draft|contributed to the writing and refining of the manuscript	conceived the idea and wrote the first draft	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5601411	28955368	SP	2	conceived the idea and wrote the first draft|contributed to the writing and refining of the manuscript	contributed to the writing and refining of the manuscript	Wrote the paper	Writing - Original Draft	YES
5392934	28412930	COW	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5392934	28412930	COW	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5392934	28412930	CWB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5392934	28412930	CWB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
5392934	28412930	CWB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5392934	28412930	CWB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5392934	28412930	DRB	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5392934	28412930	DRB	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5392934	28412930	EMM	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5392934	28412930	EMM	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5392934	28412930	JEB	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5392934	28412930	JEB	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5392934	28412930	MDP	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5392934	28412930	VS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5392934	28412930	VS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
5392934	28412930	VS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5392934	28412930	VS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408059	25906236	DRI	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408059	25906236	DRI	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408059	25906236	DRI	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408059	25906236	DRI	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408059	25906236	MED	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408059	25906236	MED	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408059	25906236	MED	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408059	25906236	MED	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408059	25906236	TM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408059	25906236	TM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408059	25906236	TM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408059	25906236	TM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408059	25906236	TM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762329	17183662	AG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762329	17183662	AG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762329	17183662	AG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762329	17183662	AM	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762329	17183662	AM	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762329	17183662	AS	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762329	17183662	CL	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762329	17183662	CL	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762329	17183662	DS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762329	17183662	DS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762329	17183662	DS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762329	17183662	FR	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762329	17183662	FR	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762329	17183662	HG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762329	17183662	HG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762329	17183662	HG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762329	17183662	JC	PLoS5	Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762329	17183662	JC	PLoS5	Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762329	17183662	JC	PLoS5	Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762329	17183662	JC	PLoS5	Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762329	17183662	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762329	17183662	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762329	17183662	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762329	17183662	KD	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762329	17183662	KM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762329	17183662	KM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762329	17183662	KM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762329	17183662	KM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762329	17183662	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762329	17183662	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762329	17183662	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762329	17183662	WW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762329	17183662	WW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762329	17183662	WW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762330	17183698	ES	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762330	17183698	ES	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762330	17183698	ES	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762330	17183698	QL	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762330	17183698	QL	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762330	17183698	RK	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762330	17183698	RK	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4347052	25741394	E. Nash	PLoS52	conceived of and designed the study|recruited patients	conceived of and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4347052	25741394	E. Nash	PLoS52	conceived of and designed the study|recruited patients	recruited patients	Performed the experiments	Investigation	YES
4347052	25741394	H. Khiroya	PLoS52	recruited patients|analysed the data	recruited patients	Performed the experiments	Investigation	YES
4347052	25741394	H. Khiroya	PLoS52	recruited patients|analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
4347052	25741394	J. Whitehouse	PLoS52	recruited patients	recruited patients	Performed the experiments	Investigation	YES
4347052	25741394	R. Pound	PLoS52	recruited patients|analysed the data	recruited patients	Performed the experiments	Investigation	YES
4347052	25741394	R. Pound	PLoS52	recruited patients|analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
4347052	25741394	R. Rashid	PLoS52	recruited patients	recruited patients	Performed the experiments	Investigation	YES
4347052	25741394	U. Qureshi	PLoS52	recruited patients|analysed the data	recruited patients	Performed the experiments	Investigation	YES
4347052	25741394	U. Qureshi	PLoS52	recruited patients|analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
4347052	25741394	all authors	PLoS52	were involved in revising and approving the manuscript	were involved in revising and approving the manuscript	Wrote the paper	Writing - Review & Editing	YES
5843814	29564389	AV	2	developed the presentation on which this manuscript is based and were involved in the drafting and final approval of the manuscript	developed the presentation on which this manuscript is based and were involved in the drafting and final approval of the manuscript	Wrote the paper	Writing - Original Draft	YES
5843814	29564389	LZ	2	developed the presentation on which this manuscript is based and were involved in the drafting and final approval of the manuscript	developed the presentation on which this manuscript is based and were involved in the drafting and final approval of the manuscript	Wrote the paper	Writing - Original Draft	YES
4408060	25905464	FC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408060	25905464	FC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408060	25905464	FC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408060	25905464	FC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408060	25905464	IM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408060	25905464	IM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408060	25905464	IM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408060	25905464	LM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Critically revised the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408060	25905464	LM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Critically revised the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408060	25905464	LM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Critically revised the manuscript	Critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4408060	25905464	MF	PLoS5	Performed the experiments|Analyzed the data|Critically revised the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4408060	25905464	MF	PLoS5	Performed the experiments|Analyzed the data|Critically revised the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4408060	25905464	MF	PLoS5	Performed the experiments|Analyzed the data|Critically revised the manuscript	Critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5392987	28415970	AWH	2	performed all of the experiments|designed experiments|wrote the manuscript	performed all of the experiments	Performed the experiments	Investigation	YES
5392987	28415970	AWH	2	performed all of the experiments|designed experiments|wrote the manuscript	designed experiments	Conceived and designed the experiments	Methodology	YES
5392987	28415970	AWH	2	performed all of the experiments|designed experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5392987	28415970	DM	2	performed all of the experiments|designed experiments	performed all of the experiments	Performed the experiments	Investigation	YES
5392987	28415970	DM	2	performed all of the experiments|designed experiments	designed experiments	Conceived and designed the experiments	Methodology	YES
5392987	28415970	JMD	2	performed all of the experiments	performed all of the experiments	Performed the experiments	Investigation	YES
5392987	28415970	KMB	2	performed all of the experiments	performed all of the experiments	Performed the experiments	Investigation	YES
5392987	28415970	MRM	2	developed smacr and provided bioinformatics analyses	developed smacr and provided bioinformatics analyses	Analyzed the data	Formal analysis	YES
5392987	28415970	MS	2	designed experiments|wrote the manuscript	designed experiments	Conceived and designed the experiments	Methodology	YES
5392987	28415970	MS	2	designed experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5674752	29110730	The author	2	is responsible for the entire manuscript	is responsible for the entire manuscript	-	-	NO
5577744	28361503	DC	2	revised and edited the manuscript	revised and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5577744	28361503	DS	2	wrote the initial draft of the manuscript	wrote the initial draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
5577744	28361503	SW	2	revised and edited the manuscript	revised and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5601412	28955361	All authors	2	significantly contributed on writing the manuscript	significantly contributed on writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5601412	28955361	BB	2	performed the meta-analysis using the described the functional genomic, bioinformatics tools	performed the meta-analysis using the described the functional genomic, bioinformatics tools	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5601412	28955361	FM	2	conceived, designed the research work|mainly wrote the article	conceived, designed the research work	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
5601412	28955361	FM	2	conceived, designed the research work|mainly wrote the article	mainly wrote the article	Wrote the paper	Writing - Original Draft	YES
5601412	28955361	TC	2	conceived, designed the research work	conceived, designed the research work	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
1762331	17183643	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762331	17183643	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1762331	17183643	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1762331	17183643	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762331	17183643	CD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762331	17183643	CD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762331	17183643	CD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762331	17183643	EM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762331	17183643	EM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762331	17183643	EM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762331	17183643	EM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762331	17183643	EM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762331	17183643	EV	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1762331	17183643	JL	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762331	17183643	JL	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762331	17183643	PD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762331	17183643	PD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1762331	17183643	PD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1762331	17183643	PD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762331	17183643	PV	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762331	17183643	PV	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5843815	29564390	All authors	2	supported the writing of this manuscript	supported the writing of this manuscript	Wrote the paper	Writing - Original Draft	YES
5843815	29564390	FR	2	were involved in data interpretation and in experimental design	were involved in data interpretation and in experimental design	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5843815	29564390	MM	2	wrote the manuscript and synthesized the labelled and non-labelled compounds|performed the animal experiments|were involved in data interpretation and in experimental design	wrote the manuscript and synthesized the labelled and non-labelled compounds	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5843815	29564390	MM	2	wrote the manuscript and synthesized the labelled and non-labelled compounds|performed the animal experiments|were involved in data interpretation and in experimental design	performed the animal experiments	Performed the experiments	Investigation	YES
5843815	29564390	MM	2	wrote the manuscript and synthesized the labelled and non-labelled compounds|performed the animal experiments|were involved in data interpretation and in experimental design	were involved in data interpretation and in experimental design	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5843815	29564390	RB	2	performed the animal experiments	performed the animal experiments	Performed the experiments	Investigation	YES
4348731	25763116	All authors	2	made a contribution in the content and writing of the manuscript including final revision of the manuscript for important intellectual content	made a contribution in the content and writing of the manuscript including final revision of the manuscript for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4348731	25763116	DC	2	collected the data|had input into the study design|performed data analysis and interpretation	collected the data	Performed the experiments	Investigation	YES
4348731	25763116	DC	2	collected the data|had input into the study design|performed data analysis and interpretation	had input into the study design	Conceived and designed the experiments	Methodology	YES
4348731	25763116	DC	2	collected the data|had input into the study design|performed data analysis and interpretation	performed data analysis and interpretation	Analyzed the data	Formal analysis	YES
4348731	25763116	MJ	2	was the principal investigator and contributed the original idea for the study|had input into the study design|performed data analysis and interpretation	was the principal investigator and contributed the original idea for the study	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
4348731	25763116	MJ	2	was the principal investigator and contributed the original idea for the study|had input into the study design|performed data analysis and interpretation	had input into the study design	Conceived and designed the experiments	Methodology	YES
4348731	25763116	MJ	2	was the principal investigator and contributed the original idea for the study|had input into the study design|performed data analysis and interpretation	performed data analysis and interpretation	Analyzed the data	Formal analysis	YES
4348731	25763116	PM	2	collected the data|had input into the study design|performed data analysis and interpretation	collected the data	Performed the experiments	Investigation	YES
4348731	25763116	PM	2	collected the data|had input into the study design|performed data analysis and interpretation	had input into the study design	Conceived and designed the experiments	Methodology	YES
4348731	25763116	PM	2	collected the data|had input into the study design|performed data analysis and interpretation	performed data analysis and interpretation	Analyzed the data	Formal analysis	YES
4348731	25763116	TB	2	had input into the study design	had input into the study design	Conceived and designed the experiments	Methodology	YES
5393005	28415976	A.E.	2	designed the study|performed the de novo assembly, methylation analysis, and comparative genomics analyses|prepared the manuscript, which was reviewed and approved by all authors	designed the study	Conceived and designed the experiments	Methodology	YES
5393005	28415976	A.E.	2	designed the study|performed the de novo assembly, methylation analysis, and comparative genomics analyses|prepared the manuscript, which was reviewed and approved by all authors	performed the de novo assembly, methylation analysis, and comparative genomics analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5393005	28415976	A.E.	2	designed the study|performed the de novo assembly, methylation analysis, and comparative genomics analyses|prepared the manuscript, which was reviewed and approved by all authors	prepared the manuscript, which was reviewed and approved by all authors	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5393005	28415976	F.V.	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5393005	28415976	S.J.M.	2	designed the study|performed the literature review, interpreted the results, and wrote additional file 3|prepared the manuscript, which was reviewed and approved by all authors	designed the study	Conceived and designed the experiments	Methodology	YES
5393005	28415976	S.J.M.	2	designed the study|performed the literature review, interpreted the results, and wrote additional file 3|prepared the manuscript, which was reviewed and approved by all authors	performed the literature review, interpreted the results, and wrote additional file 3	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5393005	28415976	S.J.M.	2	designed the study|performed the literature review, interpreted the results, and wrote additional file 3|prepared the manuscript, which was reviewed and approved by all authors	prepared the manuscript, which was reviewed and approved by all authors	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4408061	25905712	CAM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408061	25905712	CAM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408061	25905712	CAM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408061	25905712	DJG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408061	25905712	DJG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408061	25905712	DJG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408061	25905712	DJG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408061	25905712	HAM	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408061	25905712	HAM	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408061	25905712	IBJW	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408061	25905712	IBJW	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408061	25905712	IBJW	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4530206	26273630	Jingjing Gao	2	contributed equally to this work	contributed equally to this work	-	-	NO
4530206	26273630	Pan Gao	2	contributed equally to this work	contributed equally to this work	-	-	NO
4530206	26273630	Zongyao Hao	2	contributed equally to this work	contributed equally to this work	-	-	NO
1762332	17183702	CS	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762332	17183702	CV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762332	17183702	CV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762332	17183702	CV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762332	17183702	CV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762332	17183702	DF	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762332	17183702	FA	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762332	17183702	FA	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762332	17183702	IC	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762332	17183702	IC	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762332	17183702	JP	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762332	17183702	JT	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762332	17183702	MA	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762332	17183702	PY	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762332	17183702	PY	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762332	17183702	PY	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762332	17183702	PY	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762332	17183702	SP	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
6175180	29679470	A.A.	1	Analysis and interpretation of data|Critical revision	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
6175180	29679470	A.A.	1	Analysis and interpretation of data|Critical revision	Critical revision	Wrote the paper	Writing - Review & Editing	YES
6175180	29679470	A.L.	1	Study conception and design|Analysis and interpretation of data|Drafting of article|Critical revision	Study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6175180	29679470	A.L.	1	Study conception and design|Analysis and interpretation of data|Drafting of article|Critical revision	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
6175180	29679470	A.L.	1	Study conception and design|Analysis and interpretation of data|Drafting of article|Critical revision	Drafting of article	Wrote the paper	Writing - Original Draft	YES
6175180	29679470	A.L.	1	Study conception and design|Analysis and interpretation of data|Drafting of article|Critical revision	Critical revision	Wrote the paper	Writing - Review & Editing	YES
6175180	29679470	B.N.	1	Study conception and design|Analysis and interpretation of data|Drafting of article|Critical revision	Study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6175180	29679470	B.N.	1	Study conception and design|Analysis and interpretation of data|Drafting of article|Critical revision	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
6175180	29679470	B.N.	1	Study conception and design|Analysis and interpretation of data|Drafting of article|Critical revision	Drafting of article	Wrote the paper	Writing - Original Draft	YES
6175180	29679470	B.N.	1	Study conception and design|Analysis and interpretation of data|Drafting of article|Critical revision	Critical revision	Wrote the paper	Writing - Review & Editing	YES
6175180	29679470	C.R.	1	Study conception and design|Acquisition of data|Analysis and interpretation of data|Drafting of article|Critical revision	Study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6175180	29679470	C.R.	1	Study conception and design|Acquisition of data|Analysis and interpretation of data|Drafting of article|Critical revision	Acquisition of data	Performed the experiments	Investigation	YES
6175180	29679470	C.R.	1	Study conception and design|Acquisition of data|Analysis and interpretation of data|Drafting of article|Critical revision	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
6175180	29679470	C.R.	1	Study conception and design|Acquisition of data|Analysis and interpretation of data|Drafting of article|Critical revision	Drafting of article	Wrote the paper	Writing - Original Draft	YES
6175180	29679470	C.R.	1	Study conception and design|Acquisition of data|Analysis and interpretation of data|Drafting of article|Critical revision	Critical revision	Wrote the paper	Writing - Review & Editing	YES
6175180	29679470	J.C.	1	Acquisition of data	Acquisition of data	Performed the experiments	Investigation	YES
6175180	29679470	J.C.K.	1	Analysis and interpretation of data|Critical revision	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
6175180	29679470	J.C.K.	1	Analysis and interpretation of data|Critical revision	Critical revision	Wrote the paper	Writing - Review & Editing	YES
6175180	29679470	R.B.	1	Acquisition of data	Acquisition of data	Performed the experiments	Investigation	YES
6175180	29679470	R.W.	1	Acquisition of data	Acquisition of data	Performed the experiments	Investigation	YES
6175180	29679470	S.B.	1	Acquisition of data	Acquisition of data	Performed the experiments	Investigation	YES
5601413	28955364	AZ	2	designed the experiments and redacted the manuscript|performed the experiments and analyzed the results	designed the experiments and redacted the manuscript	Conceived and designed the experiments	Methodology	YES
5601413	28955364	AZ	2	designed the experiments and redacted the manuscript|performed the experiments and analyzed the results	performed the experiments and analyzed the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5601413	28955364	JA	2	designed the experiments and redacted the manuscript	designed the experiments and redacted the manuscript	Conceived and designed the experiments	Methodology	YES
5601413	28955364	JH	2	took part in the lab hosting and supervision during the az stay in their respective laboratories	took part in the lab hosting and supervision during the az stay in their respective laboratories	-	Supervision	YES
5601413	28955364	JT	2	was particularly involved in the work with the databases and tools on the web servers	was particularly involved in the work with the databases and tools on the web servers	Contributed reagents/materials/analysis tools	Software	YES
5601413	28955364	MHG	2	participated in the sequencing and interpretation of results	participated in the sequencing and interpretation of results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5601413	28955364	SH	2	took part in the lab hosting and supervision during the az stay in their respective laboratories	took part in the lab hosting and supervision during the az stay in their respective laboratories	-	Supervision	YES
4530207	26273587	Paolo Cremaschi	2	equally contributed to this work	equally contributed to this work	-	-	NO
4530207	26273587	Roberta Carriero	2	equally contributed to this work	equally contributed to this work	-	-	NO
4789131	26696272	F.M.T.	1	Concept and design of the study	Concept and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4789131	26696272	K.L.P.	1	Concept and design of the study	Concept and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4789131	26696272	S.L.	1	Concept and design of the study	Concept and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4789131	26696272	V.M.	1	Concept and design of the study	Concept and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762333	17183647	JD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762333	17183647	JD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762333	17183647	JD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762333	17183647	SM	PLoS5	Assisted in interpretation of results	Assisted in interpretation of results	Analyzed the data	Formal analysis	YES
5843816	29564391	AS	2	performed experimental work and edited the manuscript	performed experimental work and edited the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5843816	29564391	HSL	2	performed experimental work and edited the manuscript	performed experimental work and edited the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5843816	29564391	RHM	2	designed the study and edited the manuscript	designed the study and edited the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5843816	29564391	SL	2	developed the methods, performed the experimental work and drafted the manuscript	developed the methods, performed the experimental work and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5747178	29284489	KE	2	reviewed the manuscript critically|read and approved the final manuscript	reviewed the manuscript critically	Wrote the paper	Writing - Review & Editing	YES
5747178	29284489	KE	2	reviewed the manuscript critically|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5747178	29284489	MF	2	is first and corresponding author|read and approved the final manuscript	is first and corresponding author	-	-	NO
5747178	29284489	MF	2	is first and corresponding author|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
539357	15598342	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
539357	15598342	KAM	2	conceived the study, participated in its design and coordination and revised and finalized the manuscript in all its revisions	conceived the study, participated in its design and coordination and revised and finalized the manuscript in all its revisions	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Review & Editing	YES
539357	15598342	YZ	2	carried out the sequence data collection, clean-up, and analysis, and drafted the major part of the manuscript	carried out the sequence data collection, clean-up, and analysis, and drafted the major part of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5601415	28955367	CL	2	was the associate supervisor	was the associate supervisor	-	Supervision	YES
5601415	28955367	DL	2	also wrote and edited the final draft of the paper	also wrote and edited the final draft of the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5601415	28955367	GB	2	carried out the experiments and wrote the initial drafts of the paper	carried out the experiments and wrote the initial drafts of the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4408062	25905719	DLS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408062	25905719	DLS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408062	25905719	HL	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408062	25905719	HL	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408062	25905719	LY	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408062	25905719	LY	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408062	25905719	LY	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408062	25905719	LY	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408062	25905719	RMD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408062	25905719	RMD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408062	25905719	RMD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408062	25905719	RMD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408062	25905719	RMD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4825405	26814620	All authors	2	conceived and designed the study|were responsible for writing and drafting the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4825405	26814620	All authors	2	conceived and designed the study|were responsible for writing and drafting the manuscript	were responsible for writing and drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
4825405	26814620	D.H.S.	2	were responsible for writing and drafting the manuscript	were responsible for writing and drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
4825405	26814620	M.E.C.	2	were responsible for writing and drafting the manuscript	were responsible for writing and drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
4825405	26814620	Z.-A.H.	2	were responsible for writing and drafting the manuscript	were responsible for writing and drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
5395770	28420345	D.T.	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5395770	28420345	L.G.	2	performed research|analyzed data	performed research	Performed the experiments	Investigation	YES
5395770	28420345	L.G.	2	performed research|analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5395770	28420345	L.W.	2	designed the study|analyzed data|composed the paper	designed the study	Conceived and designed the experiments	Methodology	YES
5395770	28420345	L.W.	2	designed the study|analyzed data|composed the paper	analyzed data	Analyzed the data	Formal analysis	YES
5395770	28420345	L.W.	2	designed the study|analyzed data|composed the paper	composed the paper	Wrote the paper	Writing - Original Draft	YES
5395770	28420345	Q.Z.	2	performed research|analyzed data	performed research	Performed the experiments	Investigation	YES
5395770	28420345	Q.Z.	2	performed research|analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5395770	28420345	S.Y.	2	designed the study|composed the paper	designed the study	Conceived and designed the experiments	Methodology	YES
5395770	28420345	S.Y.	2	designed the study|composed the paper	composed the paper	Wrote the paper	Writing - Original Draft	YES
5395770	28420345	S.Z.	2	performed research|analyzed data	performed research	Performed the experiments	Investigation	YES
5395770	28420345	S.Z.	2	performed research|analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5395770	28420345	W.S.	2	performed research	performed research	Performed the experiments	Investigation	YES
5395770	28420345	X.Z.	2	performed research	performed research	Performed the experiments	Investigation	YES
5395770	28420345	Y.Y.	2	performed research|analyzed data	performed research	Performed the experiments	Investigation	YES
5395770	28420345	Y.Y.	2	performed research|analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
3703327	23853531	Katsuhiro Harada	2	contributed equally to this study	contributed equally to this study	-	-	NO
3703327	23853531	Satoshi Ikeda	2	contributed equally to this study	contributed equally to this study	-	-	NO
1762334	17183683	DC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762334	17183683	DC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762334	17183683	DC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762334	17183683	DC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762334	17183683	GG	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762334	17183683	GG	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762334	17183683	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762334	17183683	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762334	17183683	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762334	17183683	LD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762334	17183683	LD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762334	17183683	LD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762334	17183683	LL	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762334	17183683	LL	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1762334	17183683	VG	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1762334	17183683	VG	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1762334	17183683	VG	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762334	17183683	YA	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762334	17183683	YA	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5772725	29343272	AC	2	designed the seminar and the multidisciplinary approach|reviewed the literature regarding gender dysphoria|wrote the first version of the manuscript	designed the seminar and the multidisciplinary approach	Conceived and designed the experiments	-	YES
5772725	29343272	AC	2	designed the seminar and the multidisciplinary approach|reviewed the literature regarding gender dysphoria|wrote the first version of the manuscript	reviewed the literature regarding gender dysphoria	-	Formal analysis	YES
5772725	29343272	AC	2	designed the seminar and the multidisciplinary approach|reviewed the literature regarding gender dysphoria|wrote the first version of the manuscript	wrote the first version of the manuscript	Wrote the paper	Writing - Original Draft	YES
5772725	29343272	All	2	participants contributed to the ethical and multidisciplinary discussions during the seminars	participants contributed to the ethical and multidisciplinary discussions during the seminars	-	-	NO
5772725	29343272	All authors	2	carefully revised the first draft and accepted the final version	carefully revised the first draft and accepted the final version	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5772725	29343272	CC	2	reviewed the literature regarding gender dysphoria	reviewed the literature regarding gender dysphoria	-	Formal analysis	YES
5772725	29343272	CL	2	reviewed the literature regarding gender dysphoria	reviewed the literature regarding gender dysphoria	-	Formal analysis	YES
5772725	29343272	DC	2	designed the seminar and the multidisciplinary approach|wrote the first version of the manuscript	designed the seminar and the multidisciplinary approach	Conceived and designed the experiments	-	YES
5772725	29343272	DC	2	designed the seminar and the multidisciplinary approach|wrote the first version of the manuscript	wrote the first version of the manuscript	Wrote the paper	Writing - Original Draft	YES
5772725	29343272	FA	2	designed the seminar and the multidisciplinary approach	designed the seminar and the multidisciplinary approach	Conceived and designed the experiments	-	YES
5772725	29343272	NG	2	designed the seminar and the multidisciplinary approach	designed the seminar and the multidisciplinary approach	Conceived and designed the experiments	-	YES
5772725	29343272	NM	2	reviewed the literature regarding gender dysphoria	reviewed the literature regarding gender dysphoria	-	Formal analysis	YES
5772725	29343272	VD	2	wrote the first version of the manuscript	wrote the first version of the manuscript	Wrote the paper	Writing - Original Draft	YES
5843817	29564392	CT	2	imaging and drafted the manuscript	imaging and drafted the manuscript	Analyzed the data|Wrote the paper	Visualization|Writing - Original Draft	YES
5843817	29564392	YS	2	conceived of the study, and participated in its design and coordination and helped to draft the manuscript	conceived of the study, and participated in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
5601421	28955375	FL	PLoS52	analyzed and discussed the results	analyzed and discussed the results	Analyzed the data	Formal analysis	YES
5601421	28955375	JL	PLoS52	performed the experiments|wrote and revised the paper	performed the experiments	Performed the experiments	Investigation	YES
5601421	28955375	JL	PLoS52	performed the experiments|wrote and revised the paper	wrote and revised the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5601421	28955375	KO	PLoS52	conceived and designed the experiments|analyzed and discussed the results|wrote and revised the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5601421	28955375	KO	PLoS52	conceived and designed the experiments|analyzed and discussed the results|wrote and revised the paper	analyzed and discussed the results	Analyzed the data	Formal analysis	YES
5601421	28955375	KO	PLoS52	conceived and designed the experiments|analyzed and discussed the results|wrote and revised the paper	wrote and revised the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5601421	28955375	QQ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5601421	28955375	RW	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5601421	28955375	WD	PLoS52	conceived and designed the experiments|analyzed and discussed the results	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5601421	28955375	WD	PLoS52	conceived and designed the experiments|analyzed and discussed the results	analyzed and discussed the results	Analyzed the data	Formal analysis	YES
5601421	28955375	WZ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5601421	28955375	YH	PLoS52	analyzed and discussed the results	analyzed and discussed the results	Analyzed the data	Formal analysis	YES
5601421	28955375	YZ	PLoS52	conceived and designed the experiments|performed the experiments|wrote and revised the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5601421	28955375	YZ	PLoS52	conceived and designed the experiments|performed the experiments|wrote and revised the paper	performed the experiments	Performed the experiments	Investigation	YES
5601421	28955375	YZ	PLoS52	conceived and designed the experiments|performed the experiments|wrote and revised the paper	wrote and revised the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4530210	26273619	Heiko Sorg	2	was responsible for acquisition of data and was involved in experimental procedures and was responsible for the study design|contributed equally to this work	was responsible for acquisition of data and was involved in experimental procedures and was responsible for the study design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4530210	26273619	Heiko Sorg	2	was responsible for acquisition of data and was involved in experimental procedures and was responsible for the study design|contributed equally to this work	contributed equally to this work	-	-	NO
4530210	26273619	Peter Mailaender	2	were responsible for acquisition of data and statistical analysis	were responsible for acquisition of data and statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4530210	26273619	Robert Kraemer	2	was responsible for study design, data analysis, was involved in paper writing, and supervised all phases of the study	was responsible for study design, data analysis, was involved in paper writing, and supervised all phases of the study	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Supervision	YES
4530210	26273619	Tobias Kisch	2	was responsible for acquisition and interpretation of data and prepared the paper|contributed equally to this work	was responsible for acquisition and interpretation of data and prepared the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4530210	26273619	Tobias Kisch	2	was responsible for acquisition and interpretation of data and prepared the paper|contributed equally to this work	contributed equally to this work	-	-	NO
4530210	26273619	Vinzent Forstmeier	2	were responsible for acquisition of data and statistical analysis	were responsible for acquisition of data and statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4408063	25905772	HW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408063	25905772	HW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408063	25905772	HW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408063	25905772	XBL	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408063	25905772	YL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408063	25905772	YL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408063	25905772	YL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408063	25905772	YL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4530211	26273585	Bradley C. Martin	2	participated in project development and led the fieldwork	participated in project development and led the fieldwork	Performed the experiments	Investigation	YES
4530211	26273585	Nathan John Grills	2	conceived the study, carried out the planning, background work, and methodology development and drafted the paper	conceived the study, carried out the planning, background work, and methodology development and drafted the paper	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Writing - Original Draft	YES
4530211	26273585	Rajesh Singh	2	initiated the research, developed the methods, undertook sample selection, helped deliver the research, and undertook the initial write-up	initiated the research, developed the methods, undertook sample selection, helped deliver the research, and undertook the initial write-up	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology	YES
4530211	26273585	Rajkumari Singh	2	initiated the research, developed the methods, undertook sample selection, helped deliver the research, and undertook the initial write-up	initiated the research, developed the methods, undertook sample selection, helped deliver the research, and undertook the initial write-up	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology	YES
5852202	29577070	CP	2	have provided the scientific data for the study	have provided the scientific data for the study	Contributed reagents/materials/analysis tools	Resources	YES
5852202	29577070	FD	2	contributed to the study design and writing of the paper	contributed to the study design and writing of the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5852202	29577070	ML	2	have designed the study|have provided the scientific data for the study	have designed the study	Conceived and designed the experiments	Methodology	YES
5852202	29577070	ML	2	have designed the study|have provided the scientific data for the study	have provided the scientific data for the study	Contributed reagents/materials/analysis tools	Resources	YES
5852202	29577070	MS	2	have designed the study|have provided the scientific data for the study	have designed the study	Conceived and designed the experiments	Methodology	YES
5852202	29577070	MS	2	have designed the study|have provided the scientific data for the study	have provided the scientific data for the study	Contributed reagents/materials/analysis tools	Resources	YES
5852202	29577070	NS	2	contributed to the study design and writing of the paper	contributed to the study design and writing of the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5852202	29577070	RH	2	contributed to the study design and writing of the paper	contributed to the study design and writing of the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
1762335	17183717	CB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762335	17183717	CB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762335	17183717	CB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762335	17183717	CB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762335	17183717	CS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762335	17183717	CS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762335	17183717	CS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762335	17183717	JA	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762335	17183717	MF	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762335	17183717	MF	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762335	17183717	RG	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5601422	28955374	AN	2	designed the study, conducted the experiment, and wrote the manuscript	designed the study, conducted the experiment, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5601422	28955374	CK	2	supervised experiments at all stages and performed critical revisions of the manuscript	supervised experiments at all stages and performed critical revisions of the manuscript	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Review & Editing	YES
5601422	28955374	JH	2	assisted with experimental procedures	assisted with experimental procedures	Performed the experiments	Investigation	YES
5601422	28955374	KL	2	assisted with experimental procedures	assisted with experimental procedures	Performed the experiments	Investigation	YES
5601422	28955374	NW	2	assisted with experimental procedures	assisted with experimental procedures	Performed the experiments	Investigation	YES
5395847	28420336	KBA	2	conceived the study|wrote the manuscript and all other authors contributed their relevant portions	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5395847	28420336	KBA	2	conceived the study|wrote the manuscript and all other authors contributed their relevant portions	wrote the manuscript and all other authors contributed their relevant portions	Wrote the paper	Writing - Original Draft	YES
5395847	28420336	KP	2	conceived the study|wrote the manuscript and all other authors contributed their relevant portions|performed the computational analysis	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5395847	28420336	KP	2	conceived the study|wrote the manuscript and all other authors contributed their relevant portions|performed the computational analysis	wrote the manuscript and all other authors contributed their relevant portions	Wrote the paper	Writing - Original Draft	YES
5395847	28420336	KP	2	conceived the study|wrote the manuscript and all other authors contributed their relevant portions|performed the computational analysis	performed the computational analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5395847	28420336	KU	2	performed the experiments and generated the data	performed the experiments and generated the data	Performed the experiments	Investigation	YES
5395847	28420336	OYB	2	performed the experiments and generated the data	performed the experiments and generated the data	Performed the experiments	Investigation	YES
5395847	28420336	RS	2	conceived the study|wrote the manuscript and all other authors contributed their relevant portions	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5395847	28420336	RS	2	conceived the study|wrote the manuscript and all other authors contributed their relevant portions	wrote the manuscript and all other authors contributed their relevant portions	Wrote the paper	Writing - Original Draft	YES
5395847	28420336	SS	2	performed the experiments and generated the data	performed the experiments and generated the data	Performed the experiments	Investigation	YES
5395847	28420336	TG	2	conceived the study|wrote the manuscript and all other authors contributed their relevant portions	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5395847	28420336	TG	2	conceived the study|wrote the manuscript and all other authors contributed their relevant portions	wrote the manuscript and all other authors contributed their relevant portions	Wrote the paper	Writing - Original Draft	YES
5395847	28420336	YB	2	performed the experiments and generated the data	performed the experiments and generated the data	Performed the experiments	Investigation	YES
5395847	28420336	YP	2	performed the experiments and generated the data	performed the experiments and generated the data	Performed the experiments	Investigation	YES
5828077	29482585	AG	2	contributed to the conception and design of the work and drafted and revised the paper	contributed to the conception and design of the work and drafted and revised the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
5828077	29482585	MP	2	contributed to the conception and design of the work, commented on the paper and supervised the overall project	contributed to the conception and design of the work, commented on the paper and supervised the overall project	Conceived and designed the experiments	Conceptualization|Methodology|Supervision	YES
5828077	29482585	RJJ	2	contributed to the conception and design of the work, revised and integrated the paper	contributed to the conception and design of the work, revised and integrated the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
1762336	17183657	AP	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762336	17183657	AP	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762336	17183657	AR	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1762336	17183657	AR	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762336	17183657	JL	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762336	17183657	MG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762336	17183657	MG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762336	17183657	MG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762336	17183657	MG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5601906	28955348	YJ	2	designed the research|prepared the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
5601906	28955348	YJ	2	designed the research|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5601906	28955348	ZY	2	collected and analyzed the data|prepared the manuscript	collected and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5601906	28955348	ZY	2	collected and analyzed the data|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5932101	29756024	JPH	2	designed experiments and drafted the paper|edited the manuscript|performed experiments and analyzed data	designed experiments and drafted the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5932101	29756024	JPH	2	designed experiments and drafted the paper|edited the manuscript|performed experiments and analyzed data	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5932101	29756024	JPH	2	designed experiments and drafted the paper|edited the manuscript|performed experiments and analyzed data	performed experiments and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5932101	29756024	MDB	2	conceived and supervised the study|designed experiments and drafted the paper|edited the manuscript|performed experiments and analyzed data	conceived and supervised the study	Conceived and designed the experiments	Conceptualization|Supervision	YES
5932101	29756024	MDB	2	conceived and supervised the study|designed experiments and drafted the paper|edited the manuscript|performed experiments and analyzed data	designed experiments and drafted the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5932101	29756024	MDB	2	conceived and supervised the study|designed experiments and drafted the paper|edited the manuscript|performed experiments and analyzed data	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5932101	29756024	MDB	2	conceived and supervised the study|designed experiments and drafted the paper|edited the manuscript|performed experiments and analyzed data	performed experiments and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5932101	29756024	TL	2	edited the manuscript|performed experiments and analyzed data	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5932101	29756024	TL	2	edited the manuscript|performed experiments and analyzed data	performed experiments and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5932101	29756024	YK	2	performed experiments and analyzed data	performed experiments and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4408066	25905711	EP	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408066	25905711	EP	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408066	25905711	EP	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408066	25905711	EV	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408066	25905711	EV	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408066	25905711	EV	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408066	25905711	NI	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408066	25905711	NI	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408066	25905711	NI	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408066	25905711	NI	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408066	25905711	PR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408066	25905711	PR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408066	25905711	PR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408066	25905711	PR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408066	25905711	PR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408066	25905711	RR	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408066	25905711	RR	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408066	25905711	RR	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408066	25905711	SC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408066	25905711	SC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408066	25905711	SC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408066	25905711	SC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408066	25905711	SG	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408066	25905711	SG	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408066	25905711	SG	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408066	25905711	SR	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408066	25905711	SR	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408066	25905711	SR	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5395906	28420340	GFL	2	helped to perform the experiment and data analysis	helped to perform the experiment and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5395906	28420340	GV	2	contributed to data analysis and helped to revise the manuscript	contributed to data analysis and helped to revise the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5395906	28420340	MAPC	2	contributed to design and performed the snp genotyping, data analysis and to revise the manuscript	contributed to design and performed the snp genotyping, data analysis and to revise the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Review & Editing	YES
5395906	28420340	MCGV	2	designed the study, analyzed the data and revised the manuscript	designed the study, analyzed the data and revised the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
5395906	28420340	MZG	2	provided the genetic material	provided the genetic material	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5395906	28420340	OPHG	2	designed the kasp markers and helped to revise the manuscript	designed the kasp markers and helped to revise the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Review & Editing	YES
5395906	28420340	QS	2	contributed to design and performed the snp genotyping, data analysis and to revise the manuscript	contributed to design and performed the snp genotyping, data analysis and to revise the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Review & Editing	YES
5395906	28420340	SALC	2	performed the genetic characterization, contributed to data analysis and drafted the manuscript	performed the genetic characterization, contributed to data analysis and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5395906	28420340	TASG	2	conducted the molecular experiment and analyzed the data	conducted the molecular experiment and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5395906	28420340	VSRM	2	helped to perform the experiment and data analysis	helped to perform the experiment and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5891999	29631600	LEB	2	conceived the manuscript, did the relevant literature searches and wrote the paper	conceived the manuscript, did the relevant literature searches and wrote the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
5601976	28955354	JW	PLoS52	performed the gene functional marker mapping and the gene functional analysis|provided project resources|wrote the manuscript	performed the gene functional marker mapping and the gene functional analysis	Performed the experiments	Investigation	YES
5601976	28955354	JW	PLoS52	performed the gene functional marker mapping and the gene functional analysis|provided project resources|wrote the manuscript	provided project resources	Contributed reagents/materials/analysis tools	Resources	YES
5601976	28955354	JW	PLoS52	performed the gene functional marker mapping and the gene functional analysis|provided project resources|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5601976	28955354	RJ	PLoS52	conceived and designed the experiments|provided project resources|wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5601976	28955354	RJ	PLoS52	conceived and designed the experiments|provided project resources|wrote the manuscript	provided project resources	Contributed reagents/materials/analysis tools	Resources	YES
5601976	28955354	RJ	PLoS52	conceived and designed the experiments|provided project resources|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5601976	28955354	RL	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5601976	28955354	XM	PLoS52	analyzed the gene mapping data	analyzed the gene mapping data	Analyzed the data	Formal analysis	YES
1762337	17183664	HB	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762337	17183664	HB	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762337	17183664	JC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762337	17183664	JC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1762337	17183664	JC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762337	17183664	LS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762337	17183664	LS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762337	17183664	LS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762337	17183664	LS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762337	17183664	RC	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762337	17183664	RC	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5397707	28427327	JX	2	conceived the study and analyzed the data	conceived the study and analyzed the data	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
5397707	28427327	LC	2	conceived the study and analyzed the data	conceived the study and analyzed the data	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
5397707	28427327	XH	2	conceived the study and analyzed the data	conceived the study and analyzed the data	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
4408067	25905710	ACD	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408067	25905710	ACD	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408067	25905710	ACD	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408067	25905710	ACD	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408067	25905710	BWA	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408067	25905710	BWA	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408067	25905710	BWA	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408067	25905710	BWA	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408067	25905710	ELB	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408067	25905710	ELB	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408067	25905710	GO	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408067	25905710	GO	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408067	25905710	KRP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408067	25905710	KRP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408067	25905710	KRP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408067	25905710	KRP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408067	25905710	KRP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408067	25905710	SAK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408067	25905710	SAK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408067	25905710	SAK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408067	25905710	SAK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408067	25905710	SAK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408067	25905710	SEB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408067	25905710	SEB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408067	25905710	SEB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408067	25905710	SW	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408067	25905710	SW	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408067	25905710	SW	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408067	25905710	SW	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408067	25905710	TOM	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408067	25905710	TOM	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408067	25905710	YMK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408067	25905710	YMK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408067	25905710	YMK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5021140	26946517	B.H.	2	are responsible for concept and study design|drafted the manuscript and figures, with input from all the authors|contributed equally as senior authors	are responsible for concept and study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5021140	26946517	B.H.	2	are responsible for concept and study design|drafted the manuscript and figures, with input from all the authors|contributed equally as senior authors	drafted the manuscript and figures, with input from all the authors	Wrote the paper	Visualization|Writing - Original Draft	YES
5021140	26946517	B.H.	2	are responsible for concept and study design|drafted the manuscript and figures, with input from all the authors|contributed equally as senior authors	contributed equally as senior authors	-	-	NO
5021140	26946517	D.M.	2	were involved in sample/data acquisition and analysis	were involved in sample/data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5021140	26946517	J.L.B.	2	were involved in sample/data acquisition and analysis|drafted the manuscript and figures, with input from all the authors	were involved in sample/data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5021140	26946517	J.L.B.	2	were involved in sample/data acquisition and analysis|drafted the manuscript and figures, with input from all the authors	drafted the manuscript and figures, with input from all the authors	Wrote the paper	Visualization|Writing - Original Draft	YES
5021140	26946517	M.H.	2	are responsible for concept and study design|were involved in sample/data acquisition and analysis|drafted the manuscript and figures, with input from all the authors	are responsible for concept and study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5021140	26946517	M.H.	2	are responsible for concept and study design|were involved in sample/data acquisition and analysis|drafted the manuscript and figures, with input from all the authors	were involved in sample/data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5021140	26946517	M.H.	2	are responsible for concept and study design|were involved in sample/data acquisition and analysis|drafted the manuscript and figures, with input from all the authors	drafted the manuscript and figures, with input from all the authors	Wrote the paper	Visualization|Writing - Original Draft	YES
5021140	26946517	R.S.	2	were involved in sample/data acquisition and analysis	were involved in sample/data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5021140	26946517	S.K.	2	were involved in sample/data acquisition and analysis	were involved in sample/data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5021140	26946517	S.R.K.	2	were involved in sample/data acquisition and analysis	were involved in sample/data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5021140	26946517	T.K.	2	were involved in sample/data acquisition and analysis	were involved in sample/data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5021140	26946517	T.M.	2	are responsible for concept and study design|drafted the manuscript and figures, with input from all the authors|contributed equally as senior authors	are responsible for concept and study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5021140	26946517	T.M.	2	are responsible for concept and study design|drafted the manuscript and figures, with input from all the authors|contributed equally as senior authors	drafted the manuscript and figures, with input from all the authors	Wrote the paper	Visualization|Writing - Original Draft	YES
5021140	26946517	T.M.	2	are responsible for concept and study design|drafted the manuscript and figures, with input from all the authors|contributed equally as senior authors	contributed equally as senior authors	-	-	NO
5021140	26946517	Z.I.	2	were involved in sample/data acquisition and analysis	were involved in sample/data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5601981	28955347	DH	PLoS52	processed the microarray data and performed the pca	processed the microarray data and performed the pca	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5601981	28955347	DS	PLoS52	designed research|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
5601981	28955347	DS	PLoS52	designed research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5601981	28955347	JK	PLoS52	designed research|evaluated the microarray and performed all other experiments|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
5601981	28955347	JK	PLoS52	designed research|evaluated the microarray and performed all other experiments|wrote the paper	evaluated the microarray and performed all other experiments	Performed the experiments	Investigation	YES
5601981	28955347	JK	PLoS52	designed research|evaluated the microarray and performed all other experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5601981	28955347	NS	PLoS52	designed research|prepared rna samples and performed the microarray experiment	designed research	Conceived and designed the experiments	Methodology	YES
5601981	28955347	NS	PLoS52	designed research|prepared rna samples and performed the microarray experiment	prepared rna samples and performed the microarray experiment	Performed the experiments	Investigation	YES
5976682	29888318	IOJ	2	selected and reviewed the literature|defined the critical issues of the encapsulation problem|jointly drafted the manuscript	selected and reviewed the literature	-	Formal analysis	YES
5976682	29888318	IOJ	2	selected and reviewed the literature|defined the critical issues of the encapsulation problem|jointly drafted the manuscript	defined the critical issues of the encapsulation problem	-	-	NO
5976682	29888318	IOJ	2	selected and reviewed the literature|defined the critical issues of the encapsulation problem|jointly drafted the manuscript	jointly drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5976682	29888318	LC	2	selected and reviewed the literature|defined the critical issues of the encapsulation problem|jointly drafted the manuscript	selected and reviewed the literature	-	Formal analysis	YES
5976682	29888318	LC	2	selected and reviewed the literature|defined the critical issues of the encapsulation problem|jointly drafted the manuscript	defined the critical issues of the encapsulation problem	-	-	NO
5976682	29888318	LC	2	selected and reviewed the literature|defined the critical issues of the encapsulation problem|jointly drafted the manuscript	jointly drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5976682	29888318	UH	2	defined the critical issues of the encapsulation problem|dealt with the random walk problem|jointly drafted the manuscript	defined the critical issues of the encapsulation problem	-	-	NO
5976682	29888318	UH	2	defined the critical issues of the encapsulation problem|dealt with the random walk problem|jointly drafted the manuscript	dealt with the random walk problem	-	-	NO
5976682	29888318	UH	2	defined the critical issues of the encapsulation problem|dealt with the random walk problem|jointly drafted the manuscript	jointly drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4408068	25906165	AL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408068	25906165	AL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408068	25906165	AL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408068	25906165	CL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408068	25906165	CL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408068	25906165	CL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408068	25906165	EK	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408068	25906165	EK	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408068	25906165	EK	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408068	25906165	FK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408068	25906165	FK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408068	25906165	FK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408068	25906165	FK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408068	25906165	FK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408068	25906165	KP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408068	25906165	KP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408068	25906165	KP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408068	25906165	KP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408068	25906165	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408068	25906165	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408068	25906165	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408068	25906165	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408068	25906165	MW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408068	25906165	MW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408068	25906165	MW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408068	25906165	MW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762338	17183700	DS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762338	17183700	DS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1762338	17183700	DS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1762338	17183700	DS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762338	17183700	EM	PLoS5	Conceived and designed the experiments|Analyzed the data|Assisted in the overall coordination of the study and the critical review of the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762338	17183700	EM	PLoS5	Conceived and designed the experiments|Analyzed the data|Assisted in the overall coordination of the study and the critical review of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
1762338	17183700	EM	PLoS5	Conceived and designed the experiments|Analyzed the data|Assisted in the overall coordination of the study and the critical review of the manuscript	Assisted in the overall coordination of the study and the critical review of the manuscript	Wrote the paper	Project administration|Writing - Review & Editing	YES
1762338	17183700	FD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762338	17183700	FD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1762338	17183700	FD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1762338	17183700	FD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762338	17183700	LS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Coordinated study	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762338	17183700	LS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Coordinated study	Performed the experiments	Performed the experiments	Investigation	YES
1762338	17183700	LS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Coordinated study	Analyzed the data	Analyzed the data	Formal analysis	YES
1762338	17183700	LS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Coordinated study	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762338	17183700	LS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Coordinated study	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762338	17183700	LS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Coordinated study	Coordinated study	-	Project administration	YES
1762338	17183700	RH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762338	17183700	RH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762338	17183700	RH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762338	17183700	TS	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762338	17183700	TS	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762338	17183700	YM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762338	17183700	YM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1762338	17183700	YM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1762338	17183700	YM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5976684	29888317	LN	2	evaluated the shortened hplc assay	evaluated the shortened hplc assay	Performed the experiments	Investigation	YES
5976684	29888317	MH	2	allowed the presented work	allowed the presented work	-	-	NO
5976684	29888317	MM	2	allowed the presented work	allowed the presented work	-	-	NO
5976684	29888317	OL	2	contributed to the design of the experiments and contributed to the writing of the manuscript	contributed to the design of the experiments and contributed to the writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5976684	29888317	SM	2	also interpreted the results and contributed to the writing of the manuscript	also interpreted the results and contributed to the writing of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5976684	29888317	TW	2	allowed the presented work	allowed the presented work	-	-	NO
5976684	29888317	VP	2	interpreted the results and contributed to the writing of the manuscript	interpreted the results and contributed to the writing of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5976684	29888317	WW	2	contributed to the design of the experiments and contributed to the writing of the manuscript	contributed to the design of the experiments and contributed to the writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5397757	28427347	All authors	PLoS52	reviewed and approved the final manuscript	reviewed and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5397757	28427347	CT	PLoS52	conceived and designed the project|prepared figures and wrote and edited the manuscript	conceived and designed the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5397757	28427347	CT	PLoS52	conceived and designed the project|prepared figures and wrote and edited the manuscript	prepared figures and wrote and edited the manuscript	Wrote the paper	Visualization|Writing - Original Draft|Writing - Review & Editing	YES
5397757	28427347	GJB	PLoS52	conceived and designed the project|prepared figures and wrote and edited the manuscript	conceived and designed the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5397757	28427347	GJB	PLoS52	conceived and designed the project|prepared figures and wrote and edited the manuscript	prepared figures and wrote and edited the manuscript	Wrote the paper	Visualization|Writing - Original Draft|Writing - Review & Editing	YES
5397757	28427347	JN	PLoS52	conceived and designed the project|participated in data acquisition|analyzed the data|prepared figures and wrote and edited the manuscript	conceived and designed the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5397757	28427347	JN	PLoS52	conceived and designed the project|participated in data acquisition|analyzed the data|prepared figures and wrote and edited the manuscript	participated in data acquisition	Performed the experiments	Investigation	YES
5397757	28427347	JN	PLoS52	conceived and designed the project|participated in data acquisition|analyzed the data|prepared figures and wrote and edited the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5397757	28427347	JN	PLoS52	conceived and designed the project|participated in data acquisition|analyzed the data|prepared figures and wrote and edited the manuscript	prepared figures and wrote and edited the manuscript	Wrote the paper	Visualization|Writing - Original Draft|Writing - Review & Editing	YES
5397757	28427347	JP	PLoS52	analyzed the data|prepared figures and wrote and edited the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5397757	28427347	JP	PLoS52	analyzed the data|prepared figures and wrote and edited the manuscript	prepared figures and wrote and edited the manuscript	Wrote the paper	Visualization|Writing - Original Draft|Writing - Review & Editing	YES
5397757	28427347	KJ	PLoS52	participated in data acquisition	participated in data acquisition	Performed the experiments	Investigation	YES
5397757	28427347	KS	PLoS52	conceived and designed the project|analyzed the data|prepared figures and wrote and edited the manuscript	conceived and designed the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5397757	28427347	KS	PLoS52	conceived and designed the project|analyzed the data|prepared figures and wrote and edited the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5397757	28427347	KS	PLoS52	conceived and designed the project|analyzed the data|prepared figures and wrote and edited the manuscript	prepared figures and wrote and edited the manuscript	Wrote the paper	Visualization|Writing - Original Draft|Writing - Review & Editing	YES
5397757	28427347	MF	PLoS52	participated in data acquisition	participated in data acquisition	Performed the experiments	Investigation	YES
5397757	28427347	MM	PLoS52	participated in data acquisition	participated in data acquisition	Performed the experiments	Investigation	YES
5397757	28427347	RJT	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5397757	28427347	SY	PLoS52	participated in data acquisition	participated in data acquisition	Performed the experiments	Investigation	YES
5625589	28872277	AZ	2	analysed the results and wrote the manuscript	analysed the results and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5625589	28872277	EJA	2	conceived and designed the study and wrote the manuscript	conceived and designed the study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
5625589	28872277	LM	2	conceived and designed the study and wrote the manuscript	conceived and designed the study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
5625589	28872277	NH	2	conceived and designed the study and wrote the manuscript|analysed the results and wrote the manuscript	conceived and designed the study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
5625589	28872277	NH	2	conceived and designed the study and wrote the manuscript|analysed the results and wrote the manuscript	analysed the results and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5625589	28872277	TKP	2	analysed the results and wrote the manuscript	analysed the results and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5601990	28955350	AM	CRediT	Curation|Writing - review and editing	Curation	Analyzed the data	Data curation	YES
5601990	28955350	AM	CRediT	Curation|Writing - review and editing	Writing - review and editing	Wrote the paper	Writing - Review & Editing	YES
5601990	28955350	BL	CRediT	Curation|Writing - review and editing	Curation	Analyzed the data	Data curation	YES
5601990	28955350	BL	CRediT	Curation|Writing - review and editing	Writing - review and editing	Wrote the paper	Writing - Review & Editing	YES
5601990	28955350	GJ	CRediT	Organization|Curation|Writing - original draft	Organization	-	-	NO
5601990	28955350	GJ	CRediT	Organization|Curation|Writing - original draft	Curation	Analyzed the data	Data curation	YES
5601990	28955350	GJ	CRediT	Organization|Curation|Writing - original draft	Writing - original draft	Wrote the paper	Writing - Original Draft	YES
5601990	28955350	HC	CRediT	Curation|Writing - review and editing	Curation	Analyzed the data	Data curation	YES
5601990	28955350	HC	CRediT	Curation|Writing - review and editing	Writing - review and editing	Wrote the paper	Writing - Review & Editing	YES
5601990	28955350	JX	CRediT	Curation|Writing - review and editing	Curation	Analyzed the data	Data curation	YES
5601990	28955350	JX	CRediT	Curation|Writing - review and editing	Writing - review and editing	Wrote the paper	Writing - Review & Editing	YES
5601990	28955350	WD	CRediT	Curation|Writing - review and editing	Curation	Analyzed the data	Data curation	YES
5601990	28955350	WD	CRediT	Curation|Writing - review and editing	Writing - review and editing	Wrote the paper	Writing - Review & Editing	YES
5601990	28955350	XS	CRediT	Curation|Writing - review and editing	Curation	Analyzed the data	Data curation	YES
5601990	28955350	XS	CRediT	Curation|Writing - review and editing	Writing - review and editing	Wrote the paper	Writing - Review & Editing	YES
5601990	28955350	YZ	CRediT	Curation|Writing - review and editing	Curation	Analyzed the data	Data curation	YES
5601990	28955350	YZ	CRediT	Curation|Writing - review and editing	Writing - review and editing	Wrote the paper	Writing - Review & Editing	YES
5601990	28955350	ZW	CRediT	Organization|Curation|Writing - original draft	Organization	-	-	NO
5601990	28955350	ZW	CRediT	Organization|Curation|Writing - original draft	Curation	Analyzed the data	Data curation	YES
5601990	28955350	ZW	CRediT	Organization|Curation|Writing - original draft	Writing - original draft	Wrote the paper	Writing - Original Draft	YES
4408069	25905900	BD	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408069	25905900	BD	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4408069	25905900	CV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408069	25905900	CV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4408069	25905900	CV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4408069	25905900	FW	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408069	25905900	FW	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408069	25905900	GS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4408069	25905900	MKP	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408069	25905900	PAM	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408069	25905900	S. Shanmugam	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408069	25905900	S. Shanmugam	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408069	25905900	S. Swaminthan	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408069	25905900	S. Swaminthan	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408069	25905900	SA	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408069	25905900	SA	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408069	25905900	VS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4408069	25905900	VS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762339	17205125	AH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762339	17205125	AH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762339	17205125	AH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762339	17205125	MM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762339	17205125	MM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762339	17205125	MM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762339	17205125	MM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762339	17205125	MP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762339	17205125	MP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762339	17205125	MP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762339	17205125	PF	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762339	17205125	PF	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762339	17205125	PF	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762339	17205125	PG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762339	17205125	PG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762339	17205125	PG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762339	17205125	PG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762339	17205125	RT	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762339	17205125	RT	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762339	17205125	RT	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762339	17205125	RZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762339	17205125	RZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762339	17205125	RZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762339	17205125	RZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5397779	28427344	JGN	2	collected the samples	collected the samples	Performed the experiments	Investigation	YES
5397779	28427344	MZ	2	conceived and planned the project|drafted the manuscript and all authors revised it	conceived and planned the project	Conceived and designed the experiments	Conceptualization	YES
5397779	28427344	MZ	2	conceived and planned the project|drafted the manuscript and all authors revised it	drafted the manuscript and all authors revised it	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5397779	28427344	WC	2	performed the bioinformatics analyses|drafted the manuscript and all authors revised it	performed the bioinformatics analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5397779	28427344	WC	2	performed the bioinformatics analyses|drafted the manuscript and all authors revised it	drafted the manuscript and all authors revised it	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5397779	28427344	XFM	2	performed the practical work including molecular biology	performed the practical work including molecular biology	Performed the experiments	Investigation	YES
6063323	30101186	GH	2	conceived and coordinated the present study, supervised the chemical syntheses, participated in the design of the manuscript and finalized it	conceived and coordinated the present study, supervised the chemical syntheses, participated in the design of the manuscript and finalized it	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Supervision|Writing - Review & Editing	YES
6063323	30101186	HK	2	participated in the design of the metabolism study	participated in the design of the metabolism study	Conceived and designed the experiments	Methodology	YES
6063323	30101186	JCW	2	contributed to the metabolism study and to the finalization of the manuscript	contributed to the metabolism study and to the finalization of the manuscript	Wrote the paper	Writing - Review & Editing	YES
6063323	30101186	KS	2	participated in the design of the metabolism study	participated in the design of the metabolism study	Conceived and designed the experiments	Methodology	YES
6063323	30101186	LFG	2	contributed to the metabolism study	contributed to the metabolism study	-	-	NO
6063323	30101186	MB	2	synthesized the precursors and core structures used for the preparation of the target molecules	synthesized the precursors and core structures used for the preparation of the target molecules	Performed the experiments	Investigation	YES
6063323	30101186	MMPIs	2	application in pet imaging	application in pet imaging	Analyzed the data	Visualization	YES
6063323	30101186	SH	2	designed and executed the biodistribution experiments, participated in writing the corresponding part of the manuscript	designed and executed the biodistribution experiments, participated in writing the corresponding part of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
6063323	30101186	SW	2	designed and executed the radiochemical experiments, participated in writing the corresponding part of the manuscript	designed and executed the radiochemical experiments, participated in writing the corresponding part of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
6063323	30101186	VH	2	participated in the design of the study, did the majority of the chemical experiments, designed and composed most of the draft manuscript and participated in its finalization	participated in the design of the study, did the majority of the chemical experiments, designed and composed most of the draft manuscript and participated in its finalization	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5602128	28955352	AT	2	performed genotyping of japanese varieties	performed genotyping of japanese varieties	Performed the experiments	Investigation	YES
5602128	28955352	CU	2	contributed to the writing of the manuscript|designed the experiments	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5602128	28955352	CU	2	contributed to the writing of the manuscript|designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5602128	28955352	JB	2	led the work on australian varieties|contributed to the writing of the manuscript	led the work on australian varieties	-	-	NO
5602128	28955352	JB	2	led the work on australian varieties|contributed to the writing of the manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5602128	28955352	JH	2	performed pedigree analysis of australian|contributed to the writing of the manuscript	performed pedigree analysis of australian	Performed the experiments	Investigation	YES
5602128	28955352	JH	2	performed pedigree analysis of australian|contributed to the writing of the manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5602128	28955352	JT	2	performed genotyping of australian varieties	performed genotyping of australian varieties	Performed the experiments	Investigation	YES
5602128	28955352	MH	2	performed genotyping of australian varieties	performed genotyping of australian varieties	Performed the experiments	Investigation	YES
5602128	28955352	OS	2	led the genotype and pedigree analysis of the united kingdom varieties, annotation of bac sequences, developed the kasp and caps marker, and analyzed the hapmap data|contributed to the writing of the manuscript|designed the experiments	led the genotype and pedigree analysis of the united kingdom varieties, annotation of bac sequences, developed the kasp and caps marker, and analyzed the hapmap data	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5602128	28955352	OS	2	led the genotype and pedigree analysis of the united kingdom varieties, annotation of bac sequences, developed the kasp and caps marker, and analyzed the hapmap data|contributed to the writing of the manuscript|designed the experiments	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5602128	28955352	OS	2	led the genotype and pedigree analysis of the united kingdom varieties, annotation of bac sequences, developed the kasp and caps marker, and analyzed the hapmap data|contributed to the writing of the manuscript|designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
4530216	26273655	Kun Shi Tsai	2	contributed equally to the work and therefore should be considered equivalent authors	contributed equally to the work and therefore should be considered equivalent authors	-	-	NO
4530216	26273655	Yung-Jen Kung	2	contributed equally to the work and therefore should be considered equivalent authors	contributed equally to the work and therefore should be considered equivalent authors	-	-	NO
5053253	27438337	A.C.	2	conceived and designed the study|were responsible for data acquisition and analysis|interpreted the data and drafted the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5053253	27438337	A.C.	2	conceived and designed the study|were responsible for data acquisition and analysis|interpreted the data and drafted the manuscript	were responsible for data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5053253	27438337	A.C.	2	conceived and designed the study|were responsible for data acquisition and analysis|interpreted the data and drafted the manuscript	interpreted the data and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5053253	27438337	A.F.	2	conceived and designed the study|were responsible for data acquisition and analysis|interpreted the data and drafted the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5053253	27438337	A.F.	2	conceived and designed the study|were responsible for data acquisition and analysis|interpreted the data and drafted the manuscript	were responsible for data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5053253	27438337	A.F.	2	conceived and designed the study|were responsible for data acquisition and analysis|interpreted the data and drafted the manuscript	interpreted the data and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5053253	27438337	C.L.R.	2	were responsible for data acquisition and analysis	were responsible for data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5053253	27438337	D.S.-J.	2	were responsible for data acquisition and analysis	were responsible for data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5053253	27438337	G.C.	2	were responsible for data acquisition and analysis	were responsible for data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5053253	27438337	J.C.D.	2	were responsible for data acquisition and analysis	were responsible for data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5053253	27438337	J.F.	2	were responsible for data acquisition and analysis	were responsible for data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5053253	27438337	J.M.	2	were responsible for data acquisition and analysis	were responsible for data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5053253	27438337	J.W.S.	2	interpreted the data and drafted the manuscript	interpreted the data and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5053253	27438337	M.L.R.	2	conceived and designed the study|were responsible for data acquisition and analysis|interpreted the data and drafted the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5053253	27438337	M.L.R.	2	conceived and designed the study|were responsible for data acquisition and analysis|interpreted the data and drafted the manuscript	were responsible for data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5053253	27438337	M.L.R.	2	conceived and designed the study|were responsible for data acquisition and analysis|interpreted the data and drafted the manuscript	interpreted the data and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5053253	27438337	M.S.-D.	2	were responsible for data acquisition and analysis	were responsible for data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5053253	27438337	O.T.	2	were responsible for data acquisition and analysis	were responsible for data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5053253	27438337	R.A.	2	were responsible for data acquisition and analysis	were responsible for data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
1762340	17183704	BH	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762340	17183704	BH	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762340	17183704	DS	PLoS5	Analyzed the data|Ran the microsatellite analyses	Analyzed the data	Analyzed the data	Formal analysis	YES
1762340	17183704	DS	PLoS5	Analyzed the data|Ran the microsatellite analyses	Ran the microsatellite analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
1762340	17183704	HA	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762340	17183704	HP	PLoS5	Organised field work and data collection	Organised field work and data collection	Performed the experiments	Investigation	YES
1762340	17183704	HS	PLoS5	Conceived and designed the experiments|Organised field work and data collection	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762340	17183704	HS	PLoS5	Conceived and designed the experiments|Organised field work and data collection	Organised field work and data collection	Performed the experiments	Investigation	YES
1762340	17183704	MA	PLoS5	Analyzed the data|Wrote the paper|Ran the microsatellite analyses	Analyzed the data	Analyzed the data	Formal analysis	YES
1762340	17183704	MA	PLoS5	Analyzed the data|Wrote the paper|Ran the microsatellite analyses	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762340	17183704	MA	PLoS5	Analyzed the data|Wrote the paper|Ran the microsatellite analyses	Ran the microsatellite analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
1762340	17183704	OL	PLoS5	Conceived and designed the experiments|Analyzed the data|Evaluated genotypes for the construction of the pedigree	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762340	17183704	OL	PLoS5	Conceived and designed the experiments|Analyzed the data|Evaluated genotypes for the construction of the pedigree	Analyzed the data	Analyzed the data	Formal analysis	YES
1762340	17183704	OL	PLoS5	Conceived and designed the experiments|Analyzed the data|Evaluated genotypes for the construction of the pedigree	Evaluated genotypes for the construction of the pedigree	Performed the experiments	Investigation	YES
1762340	17183704	PW	PLoS5	Conceived and designed the experiments|Organised field work and data collection	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762340	17183704	PW	PLoS5	Conceived and designed the experiments|Organised field work and data collection	Organised field work and data collection	Performed the experiments	Investigation	YES
1762340	17183704	SB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762340	17183704	SB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762340	17183704	SB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762340	17183704	SD	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5397794	28427325	GW	PLoS52	performed research|analyzed data|wrote the paper	performed research	Performed the experiments	Investigation	YES
5397794	28427325	GW	PLoS52	performed research|analyzed data|wrote the paper	analyzed data	Analyzed the data	Formal analysis	YES
5397794	28427325	GW	PLoS52	performed research|analyzed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5397794	28427325	LS	PLoS52	performed research|analyzed data|wrote the paper	performed research	Performed the experiments	Investigation	YES
5397794	28427325	LS	PLoS52	performed research|analyzed data|wrote the paper	analyzed data	Analyzed the data	Formal analysis	YES
5397794	28427325	LS	PLoS52	performed research|analyzed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5397794	28427325	PM	PLoS52	performed research|analyzed data|wrote the paper	performed research	Performed the experiments	Investigation	YES
5397794	28427325	PM	PLoS52	performed research|analyzed data|wrote the paper	analyzed data	Analyzed the data	Formal analysis	YES
5397794	28427325	PM	PLoS52	performed research|analyzed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5397794	28427325	QL	PLoS52	designed research|analyzed data|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
5397794	28427325	QL	PLoS52	designed research|analyzed data|wrote the paper	analyzed data	Analyzed the data	Formal analysis	YES
5397794	28427325	QL	PLoS52	designed research|analyzed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5397794	28427325	SW	PLoS52	contributed new reagents or analytic tools|analyzed data|wrote the paper	contributed new reagents or analytic tools	Contributed reagents/materials/analysis tools	Resources	YES
5397794	28427325	SW	PLoS52	contributed new reagents or analytic tools|analyzed data|wrote the paper	analyzed data	Analyzed the data	Formal analysis	YES
5397794	28427325	SW	PLoS52	contributed new reagents or analytic tools|analyzed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5397794	28427325	WL	PLoS52	designed research|analyzed data|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
5397794	28427325	WL	PLoS52	designed research|analyzed data|wrote the paper	analyzed data	Analyzed the data	Formal analysis	YES
5397794	28427325	WL	PLoS52	designed research|analyzed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5397794	28427325	YZ	PLoS52	performed research|analyzed data|wrote the paper	performed research	Performed the experiments	Investigation	YES
5397794	28427325	YZ	PLoS52	performed research|analyzed data|wrote the paper	analyzed data	Analyzed the data	Formal analysis	YES
5397794	28427325	YZ	PLoS52	performed research|analyzed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408070	25906396	AH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408070	25906396	AH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408070	25906396	AH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408070	25906396	AH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408070	25906396	AH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408070	25906396	AM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4408070	25906396	GF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408070	25906396	GF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4408070	25906396	GF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4408070	25906396	GF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408070	25906396	JB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4408070	25906396	MF	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4408070	25906396	SE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408070	25906396	SE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408070	25906396	SE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408070	25906396	SE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408070	25906396	SE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408070	25906396	YB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
6150866	30294663	AAL	PLoS52	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
6150866	30294663	AD	PLoS52	analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
6150866	30294663	AD	PLoS52	analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6150866	30294663	ADW	PLoS52	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
6150866	30294663	CFM	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
6150866	30294663	ECL	PLoS52	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
6150866	30294663	JE	PLoS52	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
6150866	30294663	JV	PLoS52	designed the study|performed the experiments|analyzed the data|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
6150866	30294663	JV	PLoS52	designed the study|performed the experiments|analyzed the data|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
6150866	30294663	JV	PLoS52	designed the study|performed the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
6150866	30294663	JV	PLoS52	designed the study|performed the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6150866	30294663	MH	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
6150866	30294663	RAV	PLoS52	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
6150866	30294663	RCS	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
6150866	30294663	SS	PLoS52	designed the study|performed the experiments|analyzed the data	designed the study	Conceived and designed the experiments	Methodology	YES
6150866	30294663	SS	PLoS52	designed the study|performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
6150866	30294663	SS	PLoS52	designed the study|performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
4530217	26273607	All authors	2	read and approved the final paper	read and approved the final paper	-	-	NO
4530217	26273607	Guohui Ding	2	participated in understanding biological question and phylogenetic analysis	participated in understanding biological question and phylogenetic analysis	Performed the experiments	Investigation	YES
4530217	26273607	Hong Li	2	revised the paper|conceived and designed the study	revised the paper	Wrote the paper	Writing - Review & Editing	YES
4530217	26273607	Hong Li	2	revised the paper|conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4530217	26273607	Lin Yu	2	provided the instruction of developmental biology and collected the datasets|contributed equally to the study	provided the instruction of developmental biology and collected the datasets	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources|Supervision	YES
4530217	26273607	Lin Yu	2	provided the instruction of developmental biology and collected the datasets|contributed equally to the study	contributed equally to the study	-	-	NO
4530217	26273607	Tiancheng Liu	2	carried out the coexpression analysis and evolutionary analysis and then drafted the paper|contributed equally to the study	carried out the coexpression analysis and evolutionary analysis and then drafted the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4530217	26273607	Tiancheng Liu	2	carried out the coexpression analysis and evolutionary analysis and then drafted the paper|contributed equally to the study	contributed equally to the study	-	-	NO
4530217	26273607	Yixue Li	2	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4530217	26273607	Zhen Wang	2	participated in understanding biological question and phylogenetic analysis	participated in understanding biological question and phylogenetic analysis	Performed the experiments	Investigation	YES
5053302	27398819	B.A.C.C.	2	contributed to study concept and design|contributed to data acquisition and analysis|contributed to drafting the manuscript or figures	contributed to study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5053302	27398819	B.A.C.C.	2	contributed to study concept and design|contributed to data acquisition and analysis|contributed to drafting the manuscript or figures	contributed to data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5053302	27398819	B.A.C.C.	2	contributed to study concept and design|contributed to data acquisition and analysis|contributed to drafting the manuscript or figures	contributed to drafting the manuscript or figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5053302	27398819	C.M.S.	2	contributed to study concept and design|contributed to data acquisition and analysis|contributed to drafting the manuscript or figures	contributed to study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5053302	27398819	C.M.S.	2	contributed to study concept and design|contributed to data acquisition and analysis|contributed to drafting the manuscript or figures	contributed to data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5053302	27398819	C.M.S.	2	contributed to study concept and design|contributed to data acquisition and analysis|contributed to drafting the manuscript or figures	contributed to drafting the manuscript or figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5053302	27398819	M.V-D	2	contributed to study concept and design	contributed to study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5053302	27398819	S.E.B.	2	contributed to data acquisition and analysis	contributed to data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5053302	27398819	S.S.Z.	2	contributed to study concept and design|contributed to data acquisition and analysis|contributed to drafting the manuscript or figures	contributed to study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5053302	27398819	S.S.Z.	2	contributed to study concept and design|contributed to data acquisition and analysis|contributed to drafting the manuscript or figures	contributed to data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5053302	27398819	S.S.Z.	2	contributed to study concept and design|contributed to data acquisition and analysis|contributed to drafting the manuscript or figures	contributed to drafting the manuscript or figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5602352	28955370	AR-D	7	Idea and designed the experiments|Performed the research|Interpretation and analysis of results|Wrote and approved the manuscript	Idea and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5602352	28955370	AR-D	7	Idea and designed the experiments|Performed the research|Interpretation and analysis of results|Wrote and approved the manuscript	Performed the research	Performed the experiments	Investigation	YES
5602352	28955370	AR-D	7	Idea and designed the experiments|Performed the research|Interpretation and analysis of results|Wrote and approved the manuscript	Interpretation and analysis of results	Analyzed the data	Formal analysis	YES
5602352	28955370	AR-D	7	Idea and designed the experiments|Performed the research|Interpretation and analysis of results|Wrote and approved the manuscript	Wrote and approved the manuscript	Wrote the paper	Writing - Original Draft	YES
5602352	28955370	AR-E	7	Performed the research|Interpretation and analysis of results|Wrote and approved the manuscript	Performed the research	Performed the experiments	Investigation	YES
5602352	28955370	AR-E	7	Performed the research|Interpretation and analysis of results|Wrote and approved the manuscript	Interpretation and analysis of results	Analyzed the data	Formal analysis	YES
5602352	28955370	AR-E	7	Performed the research|Interpretation and analysis of results|Wrote and approved the manuscript	Wrote and approved the manuscript	Wrote the paper	Writing - Original Draft	YES
5602352	28955370	JR	7	Idea and designed the experiments|Performed the research|Interpretation and analysis of results|Wrote and approved the manuscript	Idea and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5602352	28955370	JR	7	Idea and designed the experiments|Performed the research|Interpretation and analysis of results|Wrote and approved the manuscript	Performed the research	Performed the experiments	Investigation	YES
5602352	28955370	JR	7	Idea and designed the experiments|Performed the research|Interpretation and analysis of results|Wrote and approved the manuscript	Interpretation and analysis of results	Analyzed the data	Formal analysis	YES
5602352	28955370	JR	7	Idea and designed the experiments|Performed the research|Interpretation and analysis of results|Wrote and approved the manuscript	Wrote and approved the manuscript	Wrote the paper	Writing - Original Draft	YES
5602352	28955370	JT	7	Idea and designed the experiments|Performed the research|Interpretation and analysis of results|Wrote and approved the manuscript	Idea and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5602352	28955370	JT	7	Idea and designed the experiments|Performed the research|Interpretation and analysis of results|Wrote and approved the manuscript	Performed the research	Performed the experiments	Investigation	YES
5602352	28955370	JT	7	Idea and designed the experiments|Performed the research|Interpretation and analysis of results|Wrote and approved the manuscript	Interpretation and analysis of results	Analyzed the data	Formal analysis	YES
5602352	28955370	JT	7	Idea and designed the experiments|Performed the research|Interpretation and analysis of results|Wrote and approved the manuscript	Wrote and approved the manuscript	Wrote the paper	Writing - Original Draft	YES
5602352	28955370	MS	7	Secured the funding|Idea and designed the experiments|Wrote and approved the manuscript	Secured the funding	-	Funding acquisition	YES
5602352	28955370	MS	7	Secured the funding|Idea and designed the experiments|Wrote and approved the manuscript	Idea and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5602352	28955370	MS	7	Secured the funding|Idea and designed the experiments|Wrote and approved the manuscript	Wrote and approved the manuscript	Wrote the paper	Writing - Original Draft	YES
5602352	28955370	RD	7	Idea and designed the experiments|Interpretation and analysis of results|Wrote and approved the manuscript	Idea and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5602352	28955370	RD	7	Idea and designed the experiments|Interpretation and analysis of results|Wrote and approved the manuscript	Interpretation and analysis of results	Analyzed the data	Formal analysis	YES
5602352	28955370	RD	7	Idea and designed the experiments|Interpretation and analysis of results|Wrote and approved the manuscript	Wrote and approved the manuscript	Wrote the paper	Writing - Original Draft	YES
4408071	25906163	AMD	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408071	25906163	AO	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4408071	25906163	FW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408071	25906163	FW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408071	25906163	FW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408071	25906163	FW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408071	25906163	HN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408071	25906163	HN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408071	25906163	HN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408071	25906163	HN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408071	25906163	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408071	25906163	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408071	25906163	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408071	25906163	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408071	25906163	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408071	25906163	JM	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408071	25906163	JM	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408071	25906163	MK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4408071	25906163	SB	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762341	17183649	AS	PLoS5	Danish twins	Danish twins	-	-	NO
1762341	17183649	BC	PLoS5	Data collection and data cleaning, australian twins	Data collection and data cleaning, australian twins	Performed the experiments	Data curation|Investigation	YES
1762341	17183649	DB	PLoS5	Contributed to final draft	Contributed to final draft	Wrote the paper	Writing - Original Draft	YES
1762341	17183649	EdG	PLoS5	Contributed to final draft	Contributed to final draft	Wrote the paper	Writing - Original Draft	YES
1762341	17183649	JH	PLoS5	British twins|Contributed to final draft	British twins	-	-	NO
1762341	17183649	JH	PLoS5	British twins|Contributed to final draft	Contributed to final draft	Wrote the paper	Writing - Original Draft	YES
1762341	17183649	JK	PLoS5	Contributed to final draft	Contributed to final draft	Wrote the paper	Writing - Original Draft	YES
1762341	17183649	JS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Dutch twins	Analyzed the data	Analyzed the data	Formal analysis	YES
1762341	17183649	JS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Dutch twins	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762341	17183649	JS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Dutch twins	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762341	17183649	JS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Dutch twins	Dutch twins	-	-	NO
1762341	17183649	JV	PLoS5	Analyzed the data|Dutch twins	Analyzed the data	Analyzed the data	Formal analysis	YES
1762341	17183649	JV	PLoS5	Analyzed the data|Dutch twins	Dutch twins	-	-	NO
1762341	17183649	KK	PLoS5	Contributed to final draft	Contributed to final draft	Wrote the paper	Writing - Original Draft	YES
1762341	17183649	NM	PLoS5	Contributed to final draft	Contributed to final draft	Wrote the paper	Writing - Original Draft	YES
1762341	17183649	NP	PLoS5	Contributed to final draft	Contributed to final draft	Wrote the paper	Writing - Original Draft	YES
1762341	17183649	RR	PLoS5	Contributed to final draft	Contributed to final draft	Wrote the paper	Writing - Original Draft	YES
1762341	17183649	TS	PLoS5	Contributed to final draft	Contributed to final draft	Wrote the paper	Writing - Original Draft	YES
1762341	17183649	UK	PLoS5	Finnish twins	Finnish twins	-	-	NO
6035429	29980201	HMO	2	is the only author of this commentary	is the only author of this commentary	-	-	NO
6173674	30363401	AJM	2	conducted radiopharmaceutical manufacturing and quality control testing	conducted radiopharmaceutical manufacturing and quality control testing	Performed the experiments	Investigation|Validation	YES
6173674	30363401	ARS	2	conducted radiopharmaceutical manufacturing and quality control testing	conducted radiopharmaceutical manufacturing and quality control testing	Performed the experiments	Investigation|Validation	YES
6173674	30363401	BDH	2	conducted radiopharmaceutical manufacturing and quality control testing|provided quality assurance and regulatory oversight	conducted radiopharmaceutical manufacturing and quality control testing	Performed the experiments	Investigation|Validation	YES
6173674	30363401	BDH	2	conducted radiopharmaceutical manufacturing and quality control testing|provided quality assurance and regulatory oversight	provided quality assurance and regulatory oversight	Performed the experiments	Supervision|Validation	YES
6173674	30363401	BGH	2	provided quality assurance and regulatory oversight	provided quality assurance and regulatory oversight	Performed the experiments	Supervision|Validation	YES
6173674	30363401	IMJ	2	conducted radiopharmaceutical manufacturing and quality control testing	conducted radiopharmaceutical manufacturing and quality control testing	Performed the experiments	Investigation|Validation	YES
6173674	30363401	JA	2	conducted radiopharmaceutical manufacturing and quality control testing	conducted radiopharmaceutical manufacturing and quality control testing	Performed the experiments	Investigation|Validation	YES
6173674	30363401	JMP	2	conducted radiopharmaceutical manufacturing and quality control testing	conducted radiopharmaceutical manufacturing and quality control testing	Performed the experiments	Investigation|Validation	YES
6173674	30363401	JS	2	conducted radiopharmaceutical manufacturing and quality control testing	conducted radiopharmaceutical manufacturing and quality control testing	Performed the experiments	Investigation|Validation	YES
6173674	30363401	MVF	2	conducted radiopharmaceutical manufacturing and quality control testing	conducted radiopharmaceutical manufacturing and quality control testing	Performed the experiments	Investigation|Validation	YES
6173674	30363401	PJHS	2	conceived and designed experiments	conceived and designed experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6173674	30363401	RAK	2	conceived and designed experiments	conceived and designed experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6173674	30363401	TJD	2	conducted radiopharmaceutical manufacturing and quality control testing	conducted radiopharmaceutical manufacturing and quality control testing	Performed the experiments	Investigation|Validation	YES
6173674	30363401	VER	2	analyzed historical pet data	analyzed historical pet data	Analyzed the data	Formal analysis	YES
6173674	30363401	WPW	2	conducted radiopharmaceutical manufacturing and quality control testing	conducted radiopharmaceutical manufacturing and quality control testing	Performed the experiments	Investigation|Validation	YES
6173674	30363401	all authors	2	analyzed data and wrote the manuscript	analyzed data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5602353	28955376	AT	2	produced the chlorophyll content analysis	produced the chlorophyll content analysis	-	-	NO
5602353	28955376	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5602353	28955376	JZ	2	designed the experiments|generated all vectors|analyzed the deep sequencing data|generated stable transgenic rice and analyzed the plants|performed the rt-pcr and real time pcr|wrote the paper with input from other authors	designed the experiments	Conceived and designed the experiments	Methodology	YES
5602353	28955376	JZ	2	designed the experiments|generated all vectors|analyzed the deep sequencing data|generated stable transgenic rice and analyzed the plants|performed the rt-pcr and real time pcr|wrote the paper with input from other authors	generated all vectors	Performed the experiments	Investigation	YES
5602353	28955376	JZ	2	designed the experiments|generated all vectors|analyzed the deep sequencing data|generated stable transgenic rice and analyzed the plants|performed the rt-pcr and real time pcr|wrote the paper with input from other authors	analyzed the deep sequencing data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5602353	28955376	JZ	2	designed the experiments|generated all vectors|analyzed the deep sequencing data|generated stable transgenic rice and analyzed the plants|performed the rt-pcr and real time pcr|wrote the paper with input from other authors	generated stable transgenic rice and analyzed the plants	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5602353	28955376	JZ	2	designed the experiments|generated all vectors|analyzed the deep sequencing data|generated stable transgenic rice and analyzed the plants|performed the rt-pcr and real time pcr|wrote the paper with input from other authors	performed the rt-pcr and real time pcr	Performed the experiments	Investigation	YES
5602353	28955376	JZ	2	designed the experiments|generated all vectors|analyzed the deep sequencing data|generated stable transgenic rice and analyzed the plants|performed the rt-pcr and real time pcr|wrote the paper with input from other authors	wrote the paper with input from other authors	Wrote the paper	Writing - Original Draft	YES
5602353	28955376	KD	2	generated all vectors|performed the transient assays in protoplasts and prepared samples for small rna sequencing|generated stable transgenic rice and analyzed the plants|wrote the paper with input from other authors	generated all vectors	Performed the experiments	Investigation	YES
5602353	28955376	KD	2	generated all vectors|performed the transient assays in protoplasts and prepared samples for small rna sequencing|generated stable transgenic rice and analyzed the plants|wrote the paper with input from other authors	performed the transient assays in protoplasts and prepared samples for small rna sequencing	Performed the experiments	Investigation	YES
5602353	28955376	KD	2	generated all vectors|performed the transient assays in protoplasts and prepared samples for small rna sequencing|generated stable transgenic rice and analyzed the plants|wrote the paper with input from other authors	generated stable transgenic rice and analyzed the plants	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5602353	28955376	KD	2	generated all vectors|performed the transient assays in protoplasts and prepared samples for small rna sequencing|generated stable transgenic rice and analyzed the plants|wrote the paper with input from other authors	wrote the paper with input from other authors	Wrote the paper	Writing - Original Draft	YES
5602353	28955376	LT	2	generated stable transgenic rice and analyzed the plants	generated stable transgenic rice and analyzed the plants	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5602353	28955376	TZ	2	analyzed the deep sequencing data	analyzed the deep sequencing data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5602353	28955376	XT	2	generated all vectors|performed the transient assays in protoplasts and prepared samples for small rna sequencing	generated all vectors	Performed the experiments	Investigation	YES
5602353	28955376	XT	2	generated all vectors|performed the transient assays in protoplasts and prepared samples for small rna sequencing	performed the transient assays in protoplasts and prepared samples for small rna sequencing	Performed the experiments	Investigation	YES
5602353	28955376	XZ	2	performed the transient assays in protoplasts and prepared samples for small rna sequencing	performed the transient assays in protoplasts and prepared samples for small rna sequencing	Performed the experiments	Investigation	YES
5602353	28955376	YC	2	generated stable transgenic rice and analyzed the plants	generated stable transgenic rice and analyzed the plants	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5602353	28955376	YQ	2	designed the experiments|analyzed the deep sequencing data|wrote the paper with input from other authors	designed the experiments	Conceived and designed the experiments	Methodology	YES
5602353	28955376	YQ	2	designed the experiments|analyzed the deep sequencing data|wrote the paper with input from other authors	analyzed the deep sequencing data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5602353	28955376	YQ	2	designed the experiments|analyzed the deep sequencing data|wrote the paper with input from other authors	wrote the paper with input from other authors	Wrote the paper	Writing - Original Draft	YES
5602353	28955376	YZ	2	designed the experiments|generated all vectors|analyzed the deep sequencing data|wrote the paper with input from other authors	designed the experiments	Conceived and designed the experiments	Methodology	YES
5602353	28955376	YZ	2	designed the experiments|generated all vectors|analyzed the deep sequencing data|wrote the paper with input from other authors	generated all vectors	Performed the experiments	Investigation	YES
5602353	28955376	YZ	2	designed the experiments|generated all vectors|analyzed the deep sequencing data|wrote the paper with input from other authors	analyzed the deep sequencing data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5602353	28955376	YZ	2	designed the experiments|generated all vectors|analyzed the deep sequencing data|wrote the paper with input from other authors	wrote the paper with input from other authors	Wrote the paper	Writing - Original Draft	YES
5602353	28955376	ZZ	2	performed the transient assays in protoplasts and prepared samples for small rna sequencing|generated stable transgenic rice and analyzed the plants	performed the transient assays in protoplasts and prepared samples for small rna sequencing	Performed the experiments	Investigation	YES
5602353	28955376	ZZ	2	performed the transient assays in protoplasts and prepared samples for small rna sequencing|generated stable transgenic rice and analyzed the plants	generated stable transgenic rice and analyzed the plants	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5399378	28427349	CD	2	designed the study, wrote and revised the manuscript	designed the study, wrote and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5399378	28427349	HN	2	designed the study, wrote and revised the manuscript	designed the study, wrote and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5399378	28427349	KW	2	designed the study, wrote and revised the manuscript|analyzed and interpreted the data|performed experimental validation	designed the study, wrote and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5399378	28427349	KW	2	designed the study, wrote and revised the manuscript|analyzed and interpreted the data|performed experimental validation	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5399378	28427349	KW	2	designed the study, wrote and revised the manuscript|analyzed and interpreted the data|performed experimental validation	performed experimental validation	Performed the experiments	Investigation|Validation	YES
5399378	28427349	PL	2	designed the study, wrote and revised the manuscript	designed the study, wrote and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5399378	28427349	TO	2	designed the study, wrote and revised the manuscript|performed experimental validation	designed the study, wrote and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5399378	28427349	TO	2	designed the study, wrote and revised the manuscript|performed experimental validation	performed experimental validation	Performed the experiments	Investigation|Validation	YES
4408072	25906076	EJ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408072	25906076	EJ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408072	25906076	EJ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408072	25906076	KB	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408072	25906076	KB	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408072	25906076	MASL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4408072	25906076	MASL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408072	25906076	MT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408072	25906076	MT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408072	25906076	MT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408072	25906076	MT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408072	25906076	MTH	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408072	25906076	MTH	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408072	25906076	YG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408072	25906076	YG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408072	25906076	YG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408072	25906076	YG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4530219	26273614	Anja K. Bosserhoff	2	designed and coordinated the study and participated in drafting the paper	designed and coordinated the study and participated in drafting the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft	YES
4530219	26273614	Peter Angele	2	both gave advice in the design of the study	both gave advice in the design of the study	Conceived and designed the experiments	Methodology	YES
4530219	26273614	Richard Kujat	2	both gave advice in the design of the study	both gave advice in the design of the study	Conceived and designed the experiments	Methodology	YES
4530219	26273614	Stephan Niebler	2	participated in drafting the paper and carried out all experiments excluding the in vitro spheroid formation assay	participated in drafting the paper and carried out all experiments excluding the in vitro spheroid formation assay	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
1762343	17183719	KK	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762343	17183719	KK	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762343	17183719	WW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762343	17183719	WW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762343	17183719	WW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762343	17183719	YX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762343	17183719	YX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762343	17183719	YX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762343	17183719	YX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5603693	28959268	All authors	2	approved the final version of the manuscript	approved the final version of the manuscript	-	-	NO
5603693	28959268	BH	2	conducted field experiments and phenotypic data analysis|scored disease severity	conducted field experiments and phenotypic data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5603693	28959268	BH	2	conducted field experiments and phenotypic data analysis|scored disease severity	scored disease severity	-	-	NO
5603693	28959268	DM	2	contributed material and statistical analyses	contributed material and statistical analyses	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5603693	28959268	MD	2	coordinated the research work	coordinated the research work	Performed the experiments	Investigation|Project administration	YES
5603693	28959268	YK	2	conducted field experiments and phenotypic data analysis|contributed material and statistical analyses|drafted the paper and produced graphical outputs	conducted field experiments and phenotypic data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5603693	28959268	YK	2	conducted field experiments and phenotypic data analysis|contributed material and statistical analyses|drafted the paper and produced graphical outputs	contributed material and statistical analyses	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5603693	28959268	YK	2	conducted field experiments and phenotypic data analysis|contributed material and statistical analyses|drafted the paper and produced graphical outputs	drafted the paper and produced graphical outputs	Wrote the paper	Writing - Original Draft	YES
6045868	30005672	JG	2	wrote concluding sub-sections and edited the manuscript	wrote concluding sub-sections and edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6045868	30005672	ZS	2	performed research, wrote the preliminary manuscript, and prepared the final manuscript	performed research, wrote the preliminary manuscript, and prepared the final manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5399393	28427329	AO	2	participated in the data acquisition and preprocessing	participated in the data acquisition and preprocessing	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5399393	28427329	DPW	2	conceived of the study and designed the research|interpreted the data and results|provided oversight and revisions	conceived of the study and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5399393	28427329	DPW	2	conceived of the study and designed the research|interpreted the data and results|provided oversight and revisions	interpreted the data and results	Analyzed the data	Formal analysis	YES
5399393	28427329	DPW	2	conceived of the study and designed the research|interpreted the data and results|provided oversight and revisions	provided oversight and revisions	Wrote the paper	Supervision|Writing - Review & Editing	YES
5399393	28427329	FJE	2	conceived of the study and designed the research|interpreted the data and results|provided oversight and revisions	conceived of the study and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5399393	28427329	FJE	2	conceived of the study and designed the research|interpreted the data and results|provided oversight and revisions	interpreted the data and results	Analyzed the data	Formal analysis	YES
5399393	28427329	FJE	2	conceived of the study and designed the research|interpreted the data and results|provided oversight and revisions	provided oversight and revisions	Wrote the paper	Supervision|Writing - Review & Editing	YES
5399393	28427329	LDB	2	conceived of the study and designed the research|performed the analyses|interpreted the data and results|wrote the initial manuscript|participated in the data acquisition and preprocessing	conceived of the study and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5399393	28427329	LDB	2	conceived of the study and designed the research|performed the analyses|interpreted the data and results|wrote the initial manuscript|participated in the data acquisition and preprocessing	performed the analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5399393	28427329	LDB	2	conceived of the study and designed the research|performed the analyses|interpreted the data and results|wrote the initial manuscript|participated in the data acquisition and preprocessing	interpreted the data and results	Analyzed the data	Formal analysis	YES
5399393	28427329	LDB	2	conceived of the study and designed the research|performed the analyses|interpreted the data and results|wrote the initial manuscript|participated in the data acquisition and preprocessing	wrote the initial manuscript	Wrote the paper	Writing - Original Draft	YES
5399393	28427329	LDB	2	conceived of the study and designed the research|performed the analyses|interpreted the data and results|wrote the initial manuscript|participated in the data acquisition and preprocessing	participated in the data acquisition and preprocessing	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5399393	28427329	MD	2	participated in the data acquisition and preprocessing	participated in the data acquisition and preprocessing	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5399393	28427329	MV	2	participated in the data acquisition and preprocessing	participated in the data acquisition and preprocessing	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
1762344	17183679	JI	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762344	17183679	JI	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762344	17183679	JI	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408074	25906072	CDS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408074	25906072	CDS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408074	25906072	CR	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408074	25906072	CR	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408074	25906072	HM	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408074	25906072	HM	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408074	25906072	MO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408074	25906072	MO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408074	25906072	MO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408074	25906072	MO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408074	25906072	MO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408074	25906072	TS	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4530220	26273653	Seong-Ho Ok	2	contributed equally to this study as co-first authors	contributed equally to this study as co-first authors	-	-	NO
4530220	26273653	Soo Hee Lee	2	contributed equally to this study as co-first authors	contributed equally to this study as co-first authors	-	-	NO
6053790	30029667	CGI	2	wrote the initial draft and prepared the manuscript for publication|prepared the manuscript for submission	wrote the initial draft and prepared the manuscript for publication	Wrote the paper	Writing - Original Draft	YES
6053790	30029667	CGI	2	wrote the initial draft and prepared the manuscript for publication|prepared the manuscript for submission	prepared the manuscript for submission	Wrote the paper	Writing - Original Draft	YES
6053790	30029667	NA	2	read and revised the initial draft and was a major contributor in writing the manuscript	read and revised the initial draft and was a major contributor in writing the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5399434	28427330	CK	2	designed the study|did the laboratory work|performed crispr analysis|contributed with interpretation and discussion of the results|drafted and revised the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5399434	28427330	CK	2	designed the study|did the laboratory work|performed crispr analysis|contributed with interpretation and discussion of the results|drafted and revised the manuscript	did the laboratory work	Performed the experiments	Investigation	YES
5399434	28427330	CK	2	designed the study|did the laboratory work|performed crispr analysis|contributed with interpretation and discussion of the results|drafted and revised the manuscript	performed crispr analysis	Performed the experiments	Investigation	YES
5399434	28427330	CK	2	designed the study|did the laboratory work|performed crispr analysis|contributed with interpretation and discussion of the results|drafted and revised the manuscript	contributed with interpretation and discussion of the results	Analyzed the data	Formal analysis	YES
5399434	28427330	CK	2	designed the study|did the laboratory work|performed crispr analysis|contributed with interpretation and discussion of the results|drafted and revised the manuscript	drafted and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5399434	28427330	EH	2	designed the study|assembled, annotated and performed comparative genomics analysis|contributed with interpretation and discussion of the results|drafted and revised the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5399434	28427330	EH	2	designed the study|assembled, annotated and performed comparative genomics analysis|contributed with interpretation and discussion of the results|drafted and revised the manuscript	assembled, annotated and performed comparative genomics analysis	Performed the experiments	Investigation	YES
5399434	28427330	EH	2	designed the study|assembled, annotated and performed comparative genomics analysis|contributed with interpretation and discussion of the results|drafted and revised the manuscript	contributed with interpretation and discussion of the results	Analyzed the data	Formal analysis	YES
5399434	28427330	EH	2	designed the study|assembled, annotated and performed comparative genomics analysis|contributed with interpretation and discussion of the results|drafted and revised the manuscript	drafted and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5399434	28427330	NPW	2	designed the study|contributed with interpretation and discussion of the results	designed the study	Conceived and designed the experiments	Methodology	YES
5399434	28427330	NPW	2	designed the study|contributed with interpretation and discussion of the results	contributed with interpretation and discussion of the results	Analyzed the data	Formal analysis	YES
5399434	28427330	TK	2	assembled, annotated and performed comparative genomics analysis|contributed with interpretation and discussion of the results|drafted and revised the manuscript	assembled, annotated and performed comparative genomics analysis	Performed the experiments	Investigation	YES
5399434	28427330	TK	2	assembled, annotated and performed comparative genomics analysis|contributed with interpretation and discussion of the results|drafted and revised the manuscript	contributed with interpretation and discussion of the results	Analyzed the data	Formal analysis	YES
5399434	28427330	TK	2	assembled, annotated and performed comparative genomics analysis|contributed with interpretation and discussion of the results|drafted and revised the manuscript	drafted and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5603696	28959269	CSL	2	organized and prepared this manuscript|contributed to the writing	organized and prepared this manuscript	Wrote the paper	Writing - Original Draft	YES
5603696	28959269	CSL	2	organized and prepared this manuscript|contributed to the writing	contributed to the writing	Wrote the paper	-	YES
5603696	28959269	JJY	2	contributed to the writing	contributed to the writing	Wrote the paper	-	YES
5603696	28959269	JLY	2	contributed to the writing	contributed to the writing	Wrote the paper	-	YES
5603696	28959269	XPG	2	contributed to the writing	contributed to the writing	Wrote the paper	-	YES
1762345	17183666	AQ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1762345	17183666	JS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1762345	17183666	MC	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762345	17183666	MC	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762345	17183666	MN	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762345	17183666	MN	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762345	17183666	MN	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762345	17183666	RF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762345	17183666	RF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762345	17183666	RF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762345	17183666	RF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5064753	26573217	E.M.	1	Concept and study design|Drafting the manuscript and figures	Concept and study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5064753	26573217	E.M.	1	Concept and study design|Drafting the manuscript and figures	Drafting the manuscript and figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5064753	26573217	E.M.K.	1	Concept and study design|Drafting the manuscript and figures	Concept and study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5064753	26573217	E.M.K.	1	Concept and study design|Drafting the manuscript and figures	Drafting the manuscript and figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5064753	26573217	J.R.M.	1	Concept and study design|Data acquisition and analysis|Drafting the manuscript and figures	Concept and study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5064753	26573217	J.R.M.	1	Concept and study design|Data acquisition and analysis|Drafting the manuscript and figures	Data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5064753	26573217	J.R.M.	1	Concept and study design|Data acquisition and analysis|Drafting the manuscript and figures	Drafting the manuscript and figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5064753	26573217	J.S.	1	Data acquisition and analysis|Drafting the manuscript and figures	Data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5064753	26573217	J.S.	1	Data acquisition and analysis|Drafting the manuscript and figures	Drafting the manuscript and figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5064753	26573217	K.B.	1	Data acquisition and analysis	Data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5064753	26573217	L.N.A.	1	Data acquisition and analysis	Data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5064753	26573217	L.P.L.	1	Data acquisition and analysis	Data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5064753	26573217	N.G.	1	Concept and study design|Data acquisition and analysis|Drafting the manuscript and figures	Concept and study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5064753	26573217	N.G.	1	Concept and study design|Data acquisition and analysis|Drafting the manuscript and figures	Data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5064753	26573217	N.G.	1	Concept and study design|Data acquisition and analysis|Drafting the manuscript and figures	Drafting the manuscript and figures	Wrote the paper	Visualization|Writing - Original Draft	YES
4408075	25906355	BHO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408075	25906355	BHO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408075	25906355	BHO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408075	25906355	BHO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408075	25906355	DLD	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408075	25906355	DLD	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408075	25906355	DLD	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408075	25906355	DLD	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408075	25906355	RDS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408075	25906355	RDS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408075	25906355	RDS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408075	25906355	TLA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408075	25906355	TLA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408075	25906355	TLA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408075	25906355	TLA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408075	25906355	WEP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408075	25906355	WEP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408075	25906355	WEP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408075	25906355	WEP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5399828	28431529	All authors	2	read, commented and approved the manuscript	read, commented and approved the manuscript	-	-	NO
5399828	28431529	EK	2	designed the study|assisted in the data analysis and the interpretation of the results	designed the study	Conceived and designed the experiments	Methodology	YES
5399828	28431529	EK	2	designed the study|assisted in the data analysis and the interpretation of the results	assisted in the data analysis and the interpretation of the results	Analyzed the data	Formal analysis	YES
5399828	28431529	TO	2	designed the study|implemented the method and performed the data analysis|drafted the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5399828	28431529	TO	2	designed the study|implemented the method and performed the data analysis|drafted the manuscript	implemented the method and performed the data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5399828	28431529	TO	2	designed the study|implemented the method and performed the data analysis|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5399828	28431529	VJ	2	designed the study|assisted in the data analysis and the interpretation of the results	designed the study	Conceived and designed the experiments	Methodology	YES
5399828	28431529	VJ	2	designed the study|assisted in the data analysis and the interpretation of the results	assisted in the data analysis and the interpretation of the results	Analyzed the data	Formal analysis	YES
6122183	30176930	CG	2	debated for the cambridge team|was a major contributor in writing the manuscript	debated for the cambridge team	-	-	NO
6122183	30176930	CG	2	debated for the cambridge team|was a major contributor in writing the manuscript	was a major contributor in writing the manuscript	Wrote the paper	Writing - Original Draft	YES
6122183	30176930	EM	2	was the convenor and chair of the debate	was the convenor and chair of the debate	-	-	NO
6122183	30176930	LZ	2	debated for the cambridge team	debated for the cambridge team	-	-	NO
6122183	30176930	MV	2	debated for the cambridge team	debated for the cambridge team	-	-	NO
5603704	28959266	CT	2	performed data analysis|wrote the manuscript	performed data analysis	Analyzed the data	Formal analysis	YES
5603704	28959266	CT	2	performed data analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5603704	28959266	GW	2	performed data analysis	performed data analysis	Analyzed the data	Formal analysis	YES
5603704	28959266	JJ	2	designed the experiments and managed the projects|performed data analysis|wrote the manuscript	designed the experiments and managed the projects	Conceived and designed the experiments	Methodology|Project administration	YES
5603704	28959266	JJ	2	designed the experiments and managed the projects|performed data analysis|wrote the manuscript	performed data analysis	Analyzed the data	Formal analysis	YES
5603704	28959266	JJ	2	designed the experiments and managed the projects|performed data analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5603704	28959266	JL	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5603704	28959266	JW	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5603704	28959266	SZ	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5603704	28959266	UM	2	performed data analysis|wrote the manuscript	performed data analysis	Analyzed the data	Formal analysis	YES
5603704	28959266	UM	2	performed data analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5603704	28959266	XL	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5603704	28959266	YL	2	designed the experiments and managed the projects|performed experiments|performed data analysis|wrote the manuscript	designed the experiments and managed the projects	Conceived and designed the experiments	Methodology|Project administration	YES
5603704	28959266	YL	2	designed the experiments and managed the projects|performed experiments|performed data analysis|wrote the manuscript	performed experiments	Performed the experiments	Investigation	YES
5603704	28959266	YL	2	designed the experiments and managed the projects|performed experiments|performed data analysis|wrote the manuscript	performed data analysis	Analyzed the data	Formal analysis	YES
5603704	28959266	YL	2	designed the experiments and managed the projects|performed experiments|performed data analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5603704	28959266	ZY	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
4740970	26865884	All authors	2	critically read and approved the final manuscript	critically read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4740970	26865884	EHH	2	contributed to the original idea of the project on the prevalence of occupational asthma in patients diagnosed of asthma in the primary healthcare system|participated in the study design|helped in coordinating the study	contributed to the original idea of the project on the prevalence of occupational asthma in patients diagnosed of asthma in the primary healthcare system	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
4740970	26865884	EHH	2	contributed to the original idea of the project on the prevalence of occupational asthma in patients diagnosed of asthma in the primary healthcare system|participated in the study design|helped in coordinating the study	participated in the study design	Conceived and designed the experiments	Methodology	YES
4740970	26865884	EHH	2	contributed to the original idea of the project on the prevalence of occupational asthma in patients diagnosed of asthma in the primary healthcare system|participated in the study design|helped in coordinating the study	helped in coordinating the study	-	Project administration	YES
4740970	26865884	GPL	2	participated in the study design	participated in the study design	Conceived and designed the experiments	Methodology	YES
4740970	26865884	JSM	2	contributed to the original idea of the project on the prevalence of occupational asthma in patients diagnosed of asthma in the primary healthcare system|participated in the study design|helped in coordinating the study	contributed to the original idea of the project on the prevalence of occupational asthma in patients diagnosed of asthma in the primary healthcare system	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
4740970	26865884	JSM	2	contributed to the original idea of the project on the prevalence of occupational asthma in patients diagnosed of asthma in the primary healthcare system|participated in the study design|helped in coordinating the study	participated in the study design	Conceived and designed the experiments	Methodology	YES
4740970	26865884	JSM	2	contributed to the original idea of the project on the prevalence of occupational asthma in patients diagnosed of asthma in the primary healthcare system|participated in the study design|helped in coordinating the study	helped in coordinating the study	-	Project administration	YES
4740970	26865884	LM	2	has participated in the statistical analysis of data|contributed to formulating the research question, conception and study design and they also participated in the elaboration research protocol and drafting of the manuscript of this paper	has participated in the statistical analysis of data	Analyzed the data	Formal analysis	YES
4740970	26865884	LM	2	has participated in the statistical analysis of data|contributed to formulating the research question, conception and study design and they also participated in the elaboration research protocol and drafting of the manuscript of this paper	contributed to formulating the research question, conception and study design and they also participated in the elaboration research protocol and drafting of the manuscript of this paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
4740970	26865884	PT	2	contributed to formulating the research question, conception and study design and they also participated in the elaboration research protocol and drafting of the manuscript of this paper	contributed to formulating the research question, conception and study design and they also participated in the elaboration research protocol and drafting of the manuscript of this paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
4740970	26865884	RPV	2	contributed to the original idea of the project on the prevalence of occupational asthma in patients diagnosed of asthma in the primary healthcare system|participated in the study design|helped in coordinating the study	contributed to the original idea of the project on the prevalence of occupational asthma in patients diagnosed of asthma in the primary healthcare system	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
4740970	26865884	RPV	2	contributed to the original idea of the project on the prevalence of occupational asthma in patients diagnosed of asthma in the primary healthcare system|participated in the study design|helped in coordinating the study	participated in the study design	Conceived and designed the experiments	Methodology	YES
4740970	26865884	RPV	2	contributed to the original idea of the project on the prevalence of occupational asthma in patients diagnosed of asthma in the primary healthcare system|participated in the study design|helped in coordinating the study	helped in coordinating the study	-	Project administration	YES
4740970	26865884	RVR	2	contributed to the original idea of the project on the prevalence of occupational asthma in patients diagnosed of asthma in the primary healthcare system|participated in the study design|helped in coordinating the study	contributed to the original idea of the project on the prevalence of occupational asthma in patients diagnosed of asthma in the primary healthcare system	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
4740970	26865884	RVR	2	contributed to the original idea of the project on the prevalence of occupational asthma in patients diagnosed of asthma in the primary healthcare system|participated in the study design|helped in coordinating the study	participated in the study design	Conceived and designed the experiments	Methodology	YES
4740970	26865884	RVR	2	contributed to the original idea of the project on the prevalence of occupational asthma in patients diagnosed of asthma in the primary healthcare system|participated in the study design|helped in coordinating the study	helped in coordinating the study	-	Project administration	YES
4740970	26865884	VRS	2	contributed to the original idea of the project on the prevalence of occupational asthma in patients diagnosed of asthma in the primary healthcare system|participated in the study design|helped in coordinating the study	contributed to the original idea of the project on the prevalence of occupational asthma in patients diagnosed of asthma in the primary healthcare system	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
4740970	26865884	VRS	2	contributed to the original idea of the project on the prevalence of occupational asthma in patients diagnosed of asthma in the primary healthcare system|participated in the study design|helped in coordinating the study	participated in the study design	Conceived and designed the experiments	Methodology	YES
4740970	26865884	VRS	2	contributed to the original idea of the project on the prevalence of occupational asthma in patients diagnosed of asthma in the primary healthcare system|participated in the study design|helped in coordinating the study	helped in coordinating the study	-	Project administration	YES
4740970	26865884	XBP	2	participated in the study design|helped in coordinating the study	participated in the study design	Conceived and designed the experiments	Methodology	YES
4740970	26865884	XBP	2	participated in the study design|helped in coordinating the study	helped in coordinating the study	-	Project administration	YES
1762346	17183723	RV	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
3703901	23861656	Yilin Zhao	2	contributed equally to this research	contributed equally to this research	-	-	NO
4296946	25992070	All authors	2	participated in the medical treatment of the patient, including postoperative care	participated in the medical treatment of the patient, including postoperative care	Performed the experiments	Investigation	YES
5066659	26575212	E.M.	2	collected the data|conducted data analysis	collected the data	Performed the experiments	Investigation	YES
5066659	26575212	E.M.	2	collected the data|conducted data analysis	conducted data analysis	Analyzed the data	Formal analysis	YES
5066659	26575212	F.D.C.	2	designed the study|conducted data analysis|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5066659	26575212	F.D.C.	2	designed the study|conducted data analysis|wrote the manuscript	conducted data analysis	Analyzed the data	Formal analysis	YES
5066659	26575212	F.D.C.	2	designed the study|conducted data analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5066659	26575212	G.L.R.	2	performed the s-eeg recordings|collected the data	performed the s-eeg recordings	Performed the experiments	Investigation	YES
5066659	26575212	G.L.R.	2	performed the s-eeg recordings|collected the data	collected the data	Performed the experiments	Investigation	YES
5066659	26575212	I.S.	2	collected the data	collected the data	Performed the experiments	Investigation	YES
5066659	26575212	L.D.G.	2	designed the study|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5066659	26575212	L.D.G.	2	designed the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5066659	26575212	L.N.	2	designed the study|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5066659	26575212	L.N.	2	designed the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5066659	26575212	M.F.	2	designed the study|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5066659	26575212	M.F.	2	designed the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5066659	26575212	P.P.	2	collected the data|wrote the manuscript	collected the data	Performed the experiments	Investigation	YES
5066659	26575212	P.P.	2	collected the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5066659	26575212	S.A.G.	2	conducted data analysis|wrote the manuscript	conducted data analysis	Analyzed the data	Formal analysis	YES
5066659	26575212	S.A.G.	2	conducted data analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4408076	25906370	AR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408076	25906370	AR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408076	25906370	AR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408076	25906370	AR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408076	25906370	AR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408076	25906370	CC	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408076	25906370	JY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408076	25906370	JY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408076	25906370	JY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408076	25906370	JY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408076	25906370	JY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408076	25906370	LC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408076	25906370	LC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408076	25906370	LC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408076	25906370	LC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408076	25906370	LC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408076	25906370	XM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408076	25906370	XM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408076	25906370	XM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408076	25906370	XM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408076	25906370	XM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408076	25906370	YX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408076	25906370	YX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408076	25906370	YX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408076	25906370	YX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408076	25906370	YX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5399841	28431495	DD	2	designed the studies described in this study	designed the studies described in this study	Conceived and designed the experiments	Methodology	YES
5399841	28431495	ES	2	conducted the fb prediction analysis|advised on bioinformatics approaches	conducted the fb prediction analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5399841	28431495	ES	2	conducted the fb prediction analysis|advised on bioinformatics approaches	advised on bioinformatics approaches	-	Formal analysis	YES
5399841	28431495	LJ	2	designed the studies described in this study|carried out the rna seq experiments with data analysis and primers extensions|completed the real time pcr|conducted the fb prediction analysis|wrote the manuscript	designed the studies described in this study	Conceived and designed the experiments	Methodology	YES
5399841	28431495	LJ	2	designed the studies described in this study|carried out the rna seq experiments with data analysis and primers extensions|completed the real time pcr|conducted the fb prediction analysis|wrote the manuscript	carried out the rna seq experiments with data analysis and primers extensions	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5399841	28431495	LJ	2	designed the studies described in this study|carried out the rna seq experiments with data analysis and primers extensions|completed the real time pcr|conducted the fb prediction analysis|wrote the manuscript	completed the real time pcr	Performed the experiments	Investigation	YES
5399841	28431495	LJ	2	designed the studies described in this study|carried out the rna seq experiments with data analysis and primers extensions|completed the real time pcr|conducted the fb prediction analysis|wrote the manuscript	conducted the fb prediction analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5399841	28431495	LJ	2	designed the studies described in this study|carried out the rna seq experiments with data analysis and primers extensions|completed the real time pcr|conducted the fb prediction analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5399841	28431495	MD	2	completed the real time pcr|performed the northern blots	completed the real time pcr	Performed the experiments	Investigation	YES
5399841	28431495	MD	2	completed the real time pcr|performed the northern blots	performed the northern blots	Performed the experiments	Investigation	YES
5603708	28959272	AN	2	designed the study, conducted the experiments, and wrote the manuscript	designed the study, conducted the experiments, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5603708	28959272	CK	2	supervised experiments at all stages and performed critical revisions of the manuscript	supervised experiments at all stages and performed critical revisions of the manuscript	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Review & Editing	YES
5603708	28959272	DP	2	designed the study, conducted the experiments, and wrote the manuscript	designed the study, conducted the experiments, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5603708	28959272	I-KK	2	assisted with experimental procedures and data analysis	assisted with experimental procedures and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5603708	28959272	J-SH	2	assisted with experimental procedures and data analysis	assisted with experimental procedures and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5603708	28959272	TA	2	assisted with experimental procedures and data analysis	assisted with experimental procedures and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6186295	30316296	Both authors	2	contributed equally	contributed equally	-	-	NO
6186295	30316296	HW	2	had the conceptual idea for this paper and did some of the background research and wrote parts of the manuscript	had the conceptual idea for this paper and did some of the background research and wrote parts of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
6186295	30316296	ML	2	continued the background research and wrote parts of the manuscript	continued the background research and wrote parts of the manuscript	Wrote the paper	Writing - Original Draft	YES
4408077	25906244	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408077	25906244	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408077	25906244	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408077	25906244	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408077	25906244	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408077	25906244	BJ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408077	25906244	BJ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408077	25906244	BJ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408077	25906244	CLC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408077	25906244	CLC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408077	25906244	CLC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408077	25906244	CLC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408077	25906244	CLC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762347	17183670	AF	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762347	17183670	AF	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762347	17183670	FG	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762347	17183670	FG	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762347	17183670	JM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762347	17183670	JM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762347	17183670	JM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762347	17183670	SS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762347	17183670	SS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5067647	26754410	B.-C.L.	2	contributed to acquisition and analysis of data	contributed to acquisition and analysis of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5067647	26754410	D.-E.K.	2	contributed to acquisition and analysis of data	contributed to acquisition and analysis of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5067647	26754410	D.-H.K.	2	contributed to acquisition and analysis of data	contributed to acquisition and analysis of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5067647	26754410	H.-J.B.	2	contributed to conception and design of the study|contributed to acquisition and analysis of data|contributed to drafting the manuscript and subsequent revisions of the manuscript	contributed to conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5067647	26754410	H.-J.B.	2	contributed to conception and design of the study|contributed to acquisition and analysis of data|contributed to drafting the manuscript and subsequent revisions of the manuscript	contributed to acquisition and analysis of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5067647	26754410	H.-J.B.	2	contributed to conception and design of the study|contributed to acquisition and analysis of data|contributed to drafting the manuscript and subsequent revisions of the manuscript	contributed to drafting the manuscript and subsequent revisions of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5067647	26754410	J.-K.C.	2	contributed to acquisition and analysis of data	contributed to acquisition and analysis of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5067647	26754410	J.-M.P.	2	contributed to conception and design of the study|contributed to acquisition and analysis of data|contributed to drafting the manuscript and subsequent revisions of the manuscript	contributed to conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5067647	26754410	J.-M.P.	2	contributed to conception and design of the study|contributed to acquisition and analysis of data|contributed to drafting the manuscript and subsequent revisions of the manuscript	contributed to acquisition and analysis of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5067647	26754410	J.-M.P.	2	contributed to conception and design of the study|contributed to acquisition and analysis of data|contributed to drafting the manuscript and subsequent revisions of the manuscript	contributed to drafting the manuscript and subsequent revisions of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5067647	26754410	J.-T.K.	2	contributed to acquisition and analysis of data	contributed to acquisition and analysis of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5067647	26754410	J.C.C.	2	contributed to acquisition and analysis of data	contributed to acquisition and analysis of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5067647	26754410	J.L.	2	contributed to conception and design of the study|contributed to acquisition and analysis of data|contributed to acquisition and analysis of data|contributed to drafting the manuscript and subsequent revisions of the manuscript	contributed to conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5067647	26754410	J.L.	2	contributed to conception and design of the study|contributed to acquisition and analysis of data|contributed to acquisition and analysis of data|contributed to drafting the manuscript and subsequent revisions of the manuscript	contributed to acquisition and analysis of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5067647	26754410	J.L.	2	contributed to conception and design of the study|contributed to acquisition and analysis of data|contributed to acquisition and analysis of data|contributed to drafting the manuscript and subsequent revisions of the manuscript	contributed to acquisition and analysis of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5067647	26754410	J.L.	2	contributed to conception and design of the study|contributed to acquisition and analysis of data|contributed to acquisition and analysis of data|contributed to drafting the manuscript and subsequent revisions of the manuscript	contributed to drafting the manuscript and subsequent revisions of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5067647	26754410	J.S.L.	2	contributed to conception and design of the study|contributed to acquisition and analysis of data|contributed to drafting the manuscript and subsequent revisions of the manuscript	contributed to conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5067647	26754410	J.S.L.	2	contributed to conception and design of the study|contributed to acquisition and analysis of data|contributed to drafting the manuscript and subsequent revisions of the manuscript	contributed to acquisition and analysis of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5067647	26754410	J.S.L.	2	contributed to conception and design of the study|contributed to acquisition and analysis of data|contributed to drafting the manuscript and subsequent revisions of the manuscript	contributed to drafting the manuscript and subsequent revisions of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5067647	26754410	K.-H.Y.	2	contributed to acquisition and analysis of data	contributed to acquisition and analysis of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5067647	26754410	K.-S.H.	2	contributed to acquisition and analysis of data	contributed to acquisition and analysis of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5067647	26754410	K.B.L.	2	contributed to acquisition and analysis of data	contributed to acquisition and analysis of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5067647	26754410	K.K.	2	contributed to acquisition and analysis of data	contributed to acquisition and analysis of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5067647	26754410	M.-K.H.	2	contributed to acquisition and analysis of data	contributed to acquisition and analysis of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5067647	26754410	P.B.G.	2	contributed to acquisition and analysis of data|contributed to drafting the manuscript and subsequent revisions of the manuscript	contributed to acquisition and analysis of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5067647	26754410	P.B.G.	2	contributed to acquisition and analysis of data|contributed to drafting the manuscript and subsequent revisions of the manuscript	contributed to drafting the manuscript and subsequent revisions of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5067647	26754410	S.J.L.	2	contributed to acquisition and analysis of data	contributed to acquisition and analysis of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5067647	26754410	T.H.P.	2	contributed to acquisition and analysis of data	contributed to acquisition and analysis of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5067647	26754410	Y.-J.C.	2	contributed to acquisition and analysis of data	contributed to acquisition and analysis of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5067647	26754410	Y.K.	2	contributed to acquisition and analysis of data	contributed to acquisition and analysis of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5603737	28959267	AK	7	work conception, all experiments concerning Nicotiana tabacum by-2 suspension cells realization, data acquisition and analysis, drafting of the manuscript	work conception, all experiments concerning Nicotiana tabacum by-2 suspension cells realization, data acquisition and analysis, drafting of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
5603737	28959267	MP	7	methodological consultant, statistical calculations, data analysis and interpretation, manuscript revision	methodological consultant, statistical calculations, data analysis and interpretation, manuscript revision	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
5603737	28959267	RR	7	research consultation/discussion, manuscript revision: language and editorial corrections	research consultation/discussion, manuscript revision: language and editorial corrections	Wrote the paper	Writing - Review & Editing	YES
4530241	26273661	Francesca Mapelli	2	contributed equally to this work	contributed equally to this work	-	-	NO
4530241	26273661	Ranya A. Amer	2	contributed equally to this work	contributed equally to this work	-	-	NO
6194698	30336788	EJC	2	conceived, researched, and wrote this contribution by himself	conceived, researched, and wrote this contribution by himself	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5399859	28431521	JPAO	2	conceived the study, collected the samples, performed the physically supported sequences mapping and contributed to the manuscript writing	conceived the study, collected the samples, performed the physically supported sequences mapping and contributed to the manuscript writing	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
5399859	28431521	JS	2	helped to prepare the rna and contributed to analyze the data	helped to prepare the rna and contributed to analyze the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5399859	28431521	LD	2	helped to prepare the rna and contributed to analyze the data	helped to prepare the rna and contributed to analyze the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5399859	28431521	LS	2	helped to prepare the rna and contributed to analyze the data	helped to prepare the rna and contributed to analyze the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5399859	28431521	MP	2	helped to prepare the rna and contributed to analyze the data	helped to prepare the rna and contributed to analyze the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5399859	28431521	OL	2	contributed to bioinformatics analyses and to the manuscript writing	contributed to bioinformatics analyses and to the manuscript writing	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5399859	28431521	RNA	2	carried out the coexpression and protein-protein interactions analysis and wrote the manuscript	carried out the coexpression and protein-protein interactions analysis and wrote the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5399859	28431521	SR	2	did the bioinformatic analysis	did the bioinformatic analysis	-	Formal analysis	YES
4408079	25905632	AO	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408079	25905632	AO	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408079	25905632	AO	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408079	25905632	CS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408079	25905632	CS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408079	25905632	CS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408079	25905632	GG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408079	25905632	GG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408079	25905632	GG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408079	25905632	GG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408079	25905632	GG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408079	25905632	JM	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408079	25905632	JM	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408079	25905632	SS	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408079	25905632	SS	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762348	17183706	FB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762348	17183706	FB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762348	17183706	FB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762348	17183706	FB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762348	17183706	IV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762348	17183706	IV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762348	17183706	IV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762348	17183706	IV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762348	17183706	IV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762348	17183706	JN	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762348	17183706	JN	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762348	17183706	KR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762348	17183706	KR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762348	17183706	KR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762348	17183706	KR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762348	17183706	KR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762348	17183706	SB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762348	17183706	SB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5604068	28959273	B-CK	PLoS52	conceived and designed the study|provided advice on the experimental design	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5604068	28959273	B-CK	PLoS52	conceived and designed the study|provided advice on the experimental design	provided advice on the experimental design	Conceived and designed the experiments	Methodology	YES
5604068	28959273	GN	PLoS52	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5604068	28959273	H-RL	PLoS52	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5604068	28959273	JJ	PLoS52	conceived and designed the study|performed experiments|analyzed the data|wrote the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5604068	28959273	JJ	PLoS52	conceived and designed the study|performed experiments|analyzed the data|wrote the manuscript	performed experiments	Performed the experiments	Investigation	YES
5604068	28959273	JJ	PLoS52	conceived and designed the study|performed experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5604068	28959273	JJ	PLoS52	conceived and designed the study|performed experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5604068	28959273	KH	PLoS52	conceived and designed the study|performed experiments|analyzed the data	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5604068	28959273	KH	PLoS52	conceived and designed the study|performed experiments|analyzed the data	performed experiments	Performed the experiments	Investigation	YES
5604068	28959273	KH	PLoS52	conceived and designed the study|performed experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5604068	28959273	PP	PLoS52	analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5604068	28959273	PP	PLoS52	analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6205791	30371347	All authors	2	reviewed the manuscript and approved the final draft	reviewed the manuscript and approved the final draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6205791	30371347	RMCF	2	contributed the section on the impacts of inequality	contributed the section on the impacts of inequality	-	-	NO
4530243	26273659	Lasitha Jayasinghe	2	contributed equally to this work	contributed equally to this work	-	-	NO
4530243	26273659	Yu-Chi Liu	2	contributed equally to this work	contributed equally to this work	-	-	NO
5069600	26991897	All authors	2	were responsible for acquisition and analysis of data	were responsible for acquisition and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5069600	26991897	H. Takashima	2	were responsible for conception and design of the study	were responsible for conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5069600	26991897	Y.H.	2	were responsible for conception and design of the study|was responsible for writing the manuscript	were responsible for conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5069600	26991897	Y.H.	2	were responsible for conception and design of the study|was responsible for writing the manuscript	was responsible for writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5401558	28431525	DS	2	was involved in the design and execution of 2d-dige experiments	was involved in the design and execution of 2d-dige experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5401558	28431525	EPM	2	oversaw the project, contributed to the design and interpretation of experiments and wrote part of the manuscript	oversaw the project, contributed to the design and interpretation of experiments and wrote part of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Supervision|Writing - Original Draft	YES
5401558	28431525	ET	2	designed prion infection experiments in pk1 cells	designed prion infection experiments in pk1 cells	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5401558	28431525	ID	2	was involved in the design and execution of bioinformatics analysis	was involved in the design and execution of bioinformatics analysis	Conceived and designed the experiments|Performed the experiments	Formal analysis|Investigation	YES
5401558	28431525	JAM	2	designed and executed experiments, performed data analysis and wrote part of the manuscript	designed and executed experiments, performed data analysis and wrote part of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5401558	28431525	JR	2	performed tandem ms analysis	performed tandem ms analysis	Performed the experiments	Investigation	YES
5401558	28431525	MEF	2	contributed with ideas and materials	contributed with ideas and materials	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceptualization|Resources	YES
5401558	28431525	PMR	2	contributed with ideas and materials	contributed with ideas and materials	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceptualization|Resources	YES
5074329	27043916	A.-L.S.	2	conceived and designed the study and critically revised the manuscript	conceived and designed the study and critically revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
5074329	27043916	All authors	2	have seen and agree with the content of the manuscript	have seen and agree with the content of the manuscript	-	-	NO
5074329	27043916	B.N.	2	provided specific input on the experimental design, and data acquisition and analysis, and contributed to manuscript writing	provided specific input on the experimental design, and data acquisition and analysis, and contributed to manuscript writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
5074329	27043916	C.-M.M.	2	provided specific input on the experimental design, and data acquisition and analysis, and contributed to manuscript writing	provided specific input on the experimental design, and data acquisition and analysis, and contributed to manuscript writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
5074329	27043916	C.A.-W.	2	designed and performed experiments, analyzed and interpreted data, and drafted the manuscript and the figures|contributed equally to this work	designed and performed experiments, analyzed and interpreted data, and drafted the manuscript and the figures	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Visualization|Writing - Original Draft	YES
5074329	27043916	C.A.-W.	2	designed and performed experiments, analyzed and interpreted data, and drafted the manuscript and the figures|contributed equally to this work	contributed equally to this work	-	-	NO
5074329	27043916	C.K.	2	conceived and designed the study and critically revised the manuscript	conceived and designed the study and critically revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
5074329	27043916	C.S.	2	provided specific input on the experimental design, and data acquisition and analysis, and contributed to manuscript writing	provided specific input on the experimental design, and data acquisition and analysis, and contributed to manuscript writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
5074329	27043916	I.A.	2	provided specific input on the experimental design, and data acquisition and analysis, and contributed to manuscript writing	provided specific input on the experimental design, and data acquisition and analysis, and contributed to manuscript writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
5074329	27043916	M.B.	2	provided specific input on the experimental design, and data acquisition and analysis, and contributed to manuscript writing	provided specific input on the experimental design, and data acquisition and analysis, and contributed to manuscript writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
5074329	27043916	M.K.S.	2	provided specific input on the experimental design, and data acquisition and analysis, and contributed to manuscript writing	provided specific input on the experimental design, and data acquisition and analysis, and contributed to manuscript writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
5074329	27043916	M.W.N.	2	provided specific input on the experimental design, and data acquisition and analysis, and contributed to manuscript writing	provided specific input on the experimental design, and data acquisition and analysis, and contributed to manuscript writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
5074329	27043916	N.M.	2	provided specific input on the experimental design, and data acquisition and analysis, and contributed to manuscript writing	provided specific input on the experimental design, and data acquisition and analysis, and contributed to manuscript writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
5074329	27043916	P.M.S.	2	provided specific input on the experimental design, and data acquisition and analysis, and contributed to manuscript writing	provided specific input on the experimental design, and data acquisition and analysis, and contributed to manuscript writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
5074329	27043916	S.H.	2	designed and performed experiments, analyzed and interpreted data, and drafted the manuscript and the figures|contributed equally to this work	designed and performed experiments, analyzed and interpreted data, and drafted the manuscript and the figures	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Visualization|Writing - Original Draft	YES
5074329	27043916	S.H.	2	designed and performed experiments, analyzed and interpreted data, and drafted the manuscript and the figures|contributed equally to this work	contributed equally to this work	-	-	NO
5074329	27043916	S.M.	2	provided specific input on the experimental design, and data acquisition and analysis, and contributed to manuscript writing	provided specific input on the experimental design, and data acquisition and analysis, and contributed to manuscript writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
4408080	25906259	HHK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4408080	25906259	SMZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408080	25906259	SMZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408080	25906259	SMZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408080	25906259	SMZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408080	25906259	SMZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408080	25906259	WW	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408080	25906259	WW	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408080	25906259	WW	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408080	25906259	XDS	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4408080	25906259	XZK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5604074	28959271	AmK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5604074	28959271	AmK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
5604074	28959271	AmK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5604074	28959271	AmK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5604074	28959271	AsK	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5604074	28959271	HT	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5604074	28959271	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5604074	28959271	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
5604074	28959271	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5604074	28959271	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5604074	28959271	NK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5604074	28959271	QD	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5604074	28959271	RG	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5604074	28959271	SM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5604074	28959271	SS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5604074	28959271	VC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762349	17183651	HF	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762349	17183651	HF	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762349	17183651	HY	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762349	17183651	HY	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762349	17183651	JX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762349	17183651	JX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762349	17183651	JX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762349	17183651	JY	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762349	17183651	JY	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762349	17183651	LB	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762349	17183651	LB	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762349	17183651	LZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762349	17183651	LZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762349	17183651	LZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762349	17183651	LZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762349	17183651	LZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762349	17183651	QF	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762349	17183651	QF	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762349	17183651	TL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762349	17183651	TL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762349	17183651	TL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762349	17183651	WX	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762349	17183651	WX	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762349	17183651	WZ	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762349	17183651	WZ	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762349	17183651	YH	PLoS5	Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762349	17183651	YH	PLoS5	Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762349	17183651	YH	PLoS5	Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762349	17183651	YH	PLoS5	Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762349	17183651	YZ	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762349	17183651	YZ	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762349	17183651	ZC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762349	17183651	ZC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762349	17183651	ZC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762349	17183651	ZQ	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762349	17183651	ZQ	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5402323	28438179	HLG	2	carried out the laboratory work	carried out the laboratory work	Performed the experiments	Investigation	YES
5402323	28438179	HPZ	2	conceived the study and participated in its design and coordination	conceived the study and participated in its design and coordination	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
5402323	28438179	JCW	2	carried out the laboratory work|wrote the manuscript	carried out the laboratory work	Performed the experiments	Investigation	YES
5402323	28438179	JCW	2	carried out the laboratory work|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5402323	28438179	LP	2	carried out the laboratory work	carried out the laboratory work	Performed the experiments	Investigation	YES
5402323	28438179	LYK	2	carried out the laboratory work|wrote the manuscript	carried out the laboratory work	Performed the experiments	Investigation	YES
5402323	28438179	LYK	2	carried out the laboratory work|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5402323	28438179	WYH	2	carried out the laboratory work	carried out the laboratory work	Performed the experiments	Investigation	YES
5402323	28438179	WYZ	2	conceived the study and participated in its design and coordination|performed the bioinformatics analysis|wrote the manuscript	conceived the study and participated in its design and coordination	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
5402323	28438179	WYZ	2	conceived the study and participated in its design and coordination|performed the bioinformatics analysis|wrote the manuscript	performed the bioinformatics analysis	Performed the experiments	Formal analysis|Investigation	YES
5402323	28438179	WYZ	2	conceived the study and participated in its design and coordination|performed the bioinformatics analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5402323	28438179	XD	2	performed the bioinformatics analysis|wrote the manuscript	performed the bioinformatics analysis	Performed the experiments	Formal analysis|Investigation	YES
5402323	28438179	XD	2	performed the bioinformatics analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5402323	28438179	YYS	2	carried out the laboratory work	carried out the laboratory work	Performed the experiments	Investigation	YES
6225580	30409214	RF	2	performed all tasks in relation to this article|read and approved the final manuscript	performed all tasks in relation to this article	Performed the experiments	Investigation	YES
6225580	30409214	RF	2	performed all tasks in relation to this article|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5084783	26971897	A.L.	2	were responsible for data acquisition and analysis|were responsible for drafting the manuscript and the figures	were responsible for data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5084783	26971897	A.L.	2	were responsible for data acquisition and analysis|were responsible for drafting the manuscript and the figures	were responsible for drafting the manuscript and the figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5084783	26971897	A.R.	2	were responsible for drafting the manuscript and the figures	were responsible for drafting the manuscript and the figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5084783	26971897	B.W.	2	were responsible for concept and study design|were responsible for drafting the manuscript and the figures	were responsible for concept and study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5084783	26971897	B.W.	2	were responsible for concept and study design|were responsible for drafting the manuscript and the figures	were responsible for drafting the manuscript and the figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5084783	26971897	F.B.E.	2	were responsible for data acquisition and analysis|were responsible for drafting the manuscript and the figures	were responsible for data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5084783	26971897	F.B.E.	2	were responsible for data acquisition and analysis|were responsible for drafting the manuscript and the figures	were responsible for drafting the manuscript and the figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5084783	26971897	F.H.G.	2	were responsible for drafting the manuscript and the figures	were responsible for drafting the manuscript and the figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5084783	26971897	F.P.B.	2	were responsible for data acquisition and analysis	were responsible for data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5084783	26971897	G.M.	2	were responsible for data acquisition and analysis	were responsible for data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5084783	26971897	G.S.	2	were responsible for data acquisition and analysis	were responsible for data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5084783	26971897	H.K.M.	2	were responsible for concept and study design|were responsible for data acquisition and analysis|were responsible for drafting the manuscript and the figures	were responsible for concept and study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5084783	26971897	H.K.M.	2	were responsible for concept and study design|were responsible for data acquisition and analysis|were responsible for drafting the manuscript and the figures	were responsible for data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5084783	26971897	H.K.M.	2	were responsible for concept and study design|were responsible for data acquisition and analysis|were responsible for drafting the manuscript and the figures	were responsible for drafting the manuscript and the figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5084783	26971897	H.W.	2	were responsible for data acquisition and analysis	were responsible for data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5084783	26971897	I.P.	2	were responsible for data acquisition and analysis|contributed equally	were responsible for data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5084783	26971897	I.P.	2	were responsible for data acquisition and analysis|contributed equally	contributed equally	-	-	NO
5084783	26971897	J.B.	2	were responsible for data acquisition and analysis	were responsible for data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5084783	26971897	J.K.	2	were responsible for data acquisition and analysis	were responsible for data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5084783	26971897	J.W.	2	were responsible for concept and study design|were responsible for drafting the manuscript and the figures	were responsible for concept and study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5084783	26971897	J.W.	2	were responsible for concept and study design|were responsible for drafting the manuscript and the figures	were responsible for drafting the manuscript and the figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5084783	26971897	L.A.	2	were responsible for data acquisition and analysis	were responsible for data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5084783	26971897	L.B.	2	were responsible for data acquisition and analysis	were responsible for data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5084783	26971897	M.B.	2	were responsible for data acquisition and analysis	were responsible for data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5084783	26971897	M.H.	2	were responsible for data acquisition and analysis	were responsible for data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5084783	26971897	M.L.	2	were responsible for data acquisition and analysis	were responsible for data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5084783	26971897	S.H.	2	were responsible for data acquisition and analysis|contributed equally	were responsible for data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5084783	26971897	S.H.	2	were responsible for data acquisition and analysis|contributed equally	contributed equally	-	-	NO
5084783	26971897	T.B.	2	were responsible for data acquisition and analysis	were responsible for data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5084783	26971897	Z.K.	2	were responsible for data acquisition and analysis	were responsible for data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3703908	23861659	Hongqi Si	2	contributed equally to this work	contributed equally to this work	-	-	NO
3703908	23861659	Manli Zhao	2	contributed equally to this work	contributed equally to this work	-	-	NO
5604078	28959270	B-BJ	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5604078	28959270	KW	PLoS52	conceived and designed the experiments|performed the experiments|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5604078	28959270	KW	PLoS52	conceived and designed the experiments|performed the experiments|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5604078	28959270	KW	PLoS52	conceived and designed the experiments|performed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5604078	28959270	LZ	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5604078	28959270	Q-LL	PLoS52	conceived and designed the experiments|performed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5604078	28959270	Q-LL	PLoS52	conceived and designed the experiments|performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5604078	28959270	Q-YL	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5604078	28959270	X-QT	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5604078	28959270	Y-HW	PLoS52	conceived and designed the experiments|performed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5604078	28959270	Y-HW	PLoS52	conceived and designed the experiments|performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5604078	28959270	Y-ZP	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5604078	28959270	Z-YB	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5604078	28959270	all authors	PLoS52	read and approved the manuscript	read and approved the manuscript	-	-	NO
4408082	25905469	CB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408082	25905469	CB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408082	25905469	CB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408082	25905469	CB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408082	25905469	FM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408082	25905469	FM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408082	25905469	FM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408082	25905469	FP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408082	25905469	FP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408082	25905469	FP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408082	25905469	FP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408082	25905469	GL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408082	25905469	GL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408082	25905469	GL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408082	25905469	LO	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4408082	25905469	NL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408082	25905469	NL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408082	25905469	NL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408082	25905469	NL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408082	25905469	OB	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4408082	25905469	OB	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408082	25905469	PA	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408082	25905469	PA	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408082	25905469	PA	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408082	25905469	PdG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408082	25905469	PdG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408082	25905469	PdG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408082	25905469	PdG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5640314	28953328	All authors	2	contributed to the writing of the manuscript and approved the final version	contributed to the writing of the manuscript and approved the final version	Wrote the paper	Writing - Original Draft	YES
5640314	28953328	FT	2	managed the cohort and transferred routinely collected data	managed the cohort and transferred routinely collected data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5640314	28953328	HP	2	managed the cohort and transferred routinely collected data	managed the cohort and transferred routinely collected data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5640314	28953328	LFJ	2	interpreted the data|provided statistical support	interpreted the data	Analyzed the data	Formal analysis	YES
5640314	28953328	LFJ	2	interpreted the data|provided statistical support	provided statistical support	Analyzed the data	Formal analysis	YES
5640314	28953328	MC	2	was responsible for all statistical analyses and the initial manuscript draft|interpreted the data	was responsible for all statistical analyses and the initial manuscript draft	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5640314	28953328	MC	2	was responsible for all statistical analyses and the initial manuscript draft|interpreted the data	interpreted the data	Analyzed the data	Formal analysis	YES
5640314	28953328	ME	2	interpreted the data	interpreted the data	Analyzed the data	Formal analysis	YES
5640314	28953328	MPF	2	managed the cohort and transferred routinely collected data	managed the cohort and transferred routinely collected data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5640314	28953328	MS	2	provided statistical support	provided statistical support	Analyzed the data	Formal analysis	YES
5640314	28953328	RW	2	managed the cohort and transferred routinely collected data|interpreted the data	managed the cohort and transferred routinely collected data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5640314	28953328	RW	2	managed the cohort and transferred routinely collected data|interpreted the data	interpreted the data	Analyzed the data	Formal analysis	YES
5084793	27130143	C.Z.	1	Concept and study design|Drafting the manuscript and the figures	Concept and study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5084793	27130143	C.Z.	1	Concept and study design|Drafting the manuscript and the figures	Drafting the manuscript and the figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5084793	27130143	H.S.	1	Concept and study design|Drafting the manuscript and the figures	Concept and study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5084793	27130143	H.S.	1	Concept and study design|Drafting the manuscript and the figures	Drafting the manuscript and the figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5084793	27130143	J.S.	1	Concept and study design|Drafting the manuscript and the figures	Concept and study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5084793	27130143	J.S.	1	Concept and study design|Drafting the manuscript and the figures	Drafting the manuscript and the figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5084793	27130143	X.W.	1	Concept and study design|Drafting the manuscript and the figures	Concept and study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5084793	27130143	X.W.	1	Concept and study design|Drafting the manuscript and the figures	Drafting the manuscript and the figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5084793	27130143	all authors	1	Data acquisition and analysis	Data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5402646	28438116	A.L.B.	2	analyzed and interpreted data, wrote the manuscript, and approved the final manuscript	analyzed and interpreted data, wrote the manuscript, and approved the final manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5402646	28438116	C.C.B.	2	analyzed and interpreted data, wrote the manuscript, and approved the final manuscript	analyzed and interpreted data, wrote the manuscript, and approved the final manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
1762350	17183687	BB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1762350	17183687	BB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1762350	17183687	BB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762350	17183687	BF	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762350	17183687	BF	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762350	17183687	BM	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762350	17183687	BM	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762350	17183687	CS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762350	17183687	CS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762350	17183687	PN	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762350	17183687	SG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762350	17183687	SG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762350	17183687	SG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762350	17183687	SG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762350	17183687	SG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762350	17183687	TS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1762350	17183687	TS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1762350	17183687	TS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5402652	28438122	AEU	2	designed and coordinated the study, advised on the analyses, and wrote the manuscript	designed and coordinated the study, advised on the analyses, and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Project administration|Writing - Original Draft	YES
5402652	28438122	CNV	2	call-sets, and wrote the manuscript|call set, wrote sections of the methods, and advised on and edited the manuscript content	call-sets, and wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5402652	28438122	CNV	2	call-sets, and wrote the manuscript|call set, wrote sections of the methods, and advised on and edited the manuscript content	call set, wrote sections of the methods, and advised on and edited the manuscript content	Performed the experiments|Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4408085	25905640	AL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408085	25905640	AL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408085	25905640	AL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408085	25905640	CL	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408085	25905640	CL	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408085	25905640	CL	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408085	25905640	KK	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408085	25905640	KK	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408085	25905640	KK	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408085	25905640	MF	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408085	25905640	PL	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5605565	28966624	AB	PLoS52	helped in qrt-pcr experiments and analysis	helped in qrt-pcr experiments and analysis	Performed the experiments	Investigation	YES
5605565	28966624	AS	PLoS52	performed the experiments|designed the experiments and prepared the manuscript|edited the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5605565	28966624	AS	PLoS52	performed the experiments|designed the experiments and prepared the manuscript|edited the manuscript	designed the experiments and prepared the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5605565	28966624	AS	PLoS52	performed the experiments|designed the experiments and prepared the manuscript|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5605565	28966624	MD	PLoS52	helped in qrt-pcr experiments and analysis	helped in qrt-pcr experiments and analysis	Performed the experiments	Investigation	YES
5605565	28966624	MM	PLoS52	designed the experiments and prepared the manuscript|edited the manuscript	designed the experiments and prepared the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5605565	28966624	MM	PLoS52	designed the experiments and prepared the manuscript|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5605565	28966624	MSM	PLoS52	performed the xanthomonas oryzae pv	performed the xanthomonas oryzae pv	Performed the experiments	Investigation	YES
5605565	28966624	PK	PLoS52	designed the experiments and prepared the manuscript|supervised the work|edited the manuscript	designed the experiments and prepared the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5605565	28966624	PK	PLoS52	designed the experiments and prepared the manuscript|supervised the work|edited the manuscript	supervised the work	-	Supervision	YES
5605565	28966624	PK	PLoS52	designed the experiments and prepared the manuscript|supervised the work|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5605565	28966624	SD	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5704900	28530043	All authors	2	reviewed and approved the final version of the manuscript	reviewed and approved the final version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5704900	28530043	BM	2	participated in study design, project implementation, and data collection	participated in study design, project implementation, and data collection	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5704900	28530043	JT	2	participated in study design, project implementation, and data collection	participated in study design, project implementation, and data collection	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5704900	28530043	KC	2	participated in study design, project implementation, data collection, interpretation of data, and revision of the manuscript	participated in study design, project implementation, data collection, interpretation of data, and revision of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Review & Editing	YES
5704900	28530043	KL	2	participated in study design, project implementation, and data collection	participated in study design, project implementation, and data collection	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5704900	28530043	MM	2	participated in study design, statistical analysis, interpretation of data, and revision of the manuscript	participated in study design, statistical analysis, interpretation of data, and revision of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
5704900	28530043	PL	2	participated in study design, project implementation, and data collection	participated in study design, project implementation, and data collection	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5704900	28530043	PS	2	participated in study design, project implementation, and data collection	participated in study design, project implementation, and data collection	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5704900	28530043	RL	2	participated in study design, project implementation, statistical analysis, interpretation of data, and drafting and revision of the manuscript	participated in study design, project implementation, statistical analysis, interpretation of data, and drafting and revision of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5704900	28530043	VB	2	participated in study design, project implementation, and data collection	participated in study design, project implementation, and data collection	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5704900	28530043	VT	2	performed data analysis	performed data analysis	Analyzed the data	Formal analysis	YES
5704900	28530043	WN	2	participated in study design, project implementation, and data collection	participated in study design, project implementation, and data collection	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5704900	28530043	WP	2	participated in study design, project implementation, and data collection	participated in study design, project implementation, and data collection	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5704900	28530043	YN	2	participated in study design, project implementation, and data collection	participated in study design, project implementation, and data collection	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5105678	27464262	A.A.	1	Data acquisition and analysis	Data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5105678	27464262	A.H.Z.	1	Data acquisition and analysis	Data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5105678	27464262	A.J.G.	1	Data acquisition and analysis	Data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5105678	27464262	A.L.	1	Data acquisition and analysis	Data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5105678	27464262	A.S.	1	Data acquisition and analysis	Data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5105678	27464262	B.A.C.C.	1	Study concept and design|Data acquisition and analysis	Study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5105678	27464262	B.A.C.C.	1	Study concept and design|Data acquisition and analysis	Data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5105678	27464262	C.B.	1	Data acquisition and analysis	Data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5105678	27464262	C.C.	1	Data acquisition and analysis	Data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5105678	27464262	D.P.	1	Data acquisition and analysis	Data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5105678	27464262	D.S.G.	1	Data acquisition and analysis	Data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5105678	27464262	D.T.O.	1	Data acquisition and analysis	Data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5105678	27464262	E.C.-H.	1	Data acquisition and analysis	Data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5105678	27464262	E.M.	1	Data acquisition and analysis	Data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5105678	27464262	G.R.C.	1	Data acquisition and analysis	Data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5105678	27464262	H.-C.v.B.	1	Data acquisition and analysis	Data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5105678	27464262	J.G.	1	Data acquisition and analysis	Data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5105678	27464262	J.M.G.	1	Data acquisition and analysis	Data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5105678	27464262	J.R.O.	1	Study concept and design	Study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5105678	27464262	L.S.	1	Data acquisition and analysis	Data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5105678	27464262	M.B.	1	Data acquisition and analysis	Data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5105678	27464262	N.P.	1	Data acquisition and analysis	Data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5105678	27464262	P.-A.G.	1	Study concept and design|Data acquisition and analysis	Study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5105678	27464262	P.-A.G.	1	Study concept and design|Data acquisition and analysis	Data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5105678	27464262	P.Q.	1	Data acquisition and analysis	Data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5105678	27464262	R.G.	1	Data acquisition and analysis	Data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5105678	27464262	R.G.H.	1	Study concept and design|Data acquisition and analysis	Study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5105678	27464262	R.G.H.	1	Study concept and design|Data acquisition and analysis	Data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5105678	27464262	R.K.	1	Data acquisition and analysis	Data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5105678	27464262	R.L.	1	Data acquisition and analysis	Data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5105678	27464262	S.B.	1	Study concept and design	Study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5105678	27464262	S.C.	1	Data acquisition and analysis	Data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5105678	27464262	S.L.H.	1	Study concept and design	Study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5105678	27464262	S.S.Z.	1	Data acquisition and analysis	Data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5105678	27464262	V.P.	1	Data acquisition and analysis	Data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5105678	27464262	W.A.S.	1	Data acquisition and analysis	Data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
1762351	17183701	CB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762351	17183701	CB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762351	17183701	CB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762351	17183701	CB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762351	17183701	CK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762351	17183701	CK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762351	17183701	CK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762351	17183701	CK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762351	17183701	JP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4408087	25905460	JLW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408087	25905460	JLW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408087	25905460	JLW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408087	25905460	JLW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408087	25905460	JY	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408087	25905460	JY	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408087	25905460	LT	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408087	25905460	LT	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408087	25905460	PP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408087	25905460	PP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408087	25905460	PP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408087	25905460	PP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4531157	26290873	Charles Guenancia	2	contributed equally to this work	contributed equally to this work	-	-	NO
4531157	26290873	Charline Pujos	2	contributed equally to this work	contributed equally to this work	-	-	NO
5404281	28438136	ALA	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5404281	28438136	DWB	2	conceived the idea for the study and selected the samples for sequencing|wrote the manuscript	conceived the idea for the study and selected the samples for sequencing	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5404281	28438136	DWB	2	conceived the idea for the study and selected the samples for sequencing|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5404281	28438136	ET	2	developed analyses pipelines and provided guidance on usage	developed analyses pipelines and provided guidance on usage	Analyzed the data	Formal analysis|Supervision	YES
5404281	28438136	IRP	2	prepared the samples for sequencing	prepared the samples for sequencing	Performed the experiments	Investigation	YES
5404281	28438136	LE	2	analysed the short read data	analysed the short read data	Analyzed the data	Formal analysis	YES
5404281	28438136	RIK	2	analysed the long read data|analysed the short read data|wrote the manuscript	analysed the long read data	Analyzed the data	Formal analysis	YES
5404281	28438136	RIK	2	analysed the long read data|analysed the short read data|wrote the manuscript	analysed the short read data	Analyzed the data	Formal analysis	YES
5404281	28438136	RIK	2	analysed the long read data|analysed the short read data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3155201	21841971	CR	2	provided intellectual input, help in the statistics, and reviewed the manuscript	provided intellectual input, help in the statistics, and reviewed the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
3155201	21841971	EC	2	performed the blood sampling and analyzed the data as well as critically reviewing the manuscript	performed the blood sampling and analyzed the data as well as critically reviewing the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
3155201	21841971	HMW	2	provided advice in the conception of the study and interpretation of the data, performed experiments, and critically reviewed the manuscript	provided advice in the conception of the study and interpretation of the data, performed experiments, and critically reviewed the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Resources|Writing - Review & Editing	YES
3155201	21841971	HRS	2	is the pi of the study and is involved in all aspects of this work from design to writing	is the pi of the study and is involved in all aspects of this work from design to writing	Conceived and designed the experiments|Wrote the paper	Methodology	YES
3155201	21841971	JOP	2	helped to statistically analyze and interpret the data and considerably improved the manuscript in writing	helped to statistically analyze and interpret the data and considerably improved the manuscript in writing	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
3155201	21841971	KPW	2	helped in the kinetic analyses and critically reviewed the manuscript	helped in the kinetic analyses and critically reviewed the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
3155201	21841971	MCK	2	performed all animal experiments, developed the methodology, analyzed the data, and wrote the manuscript	performed all animal experiments, developed the methodology, analyzed the data, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
3155201	21841971	SCH	2	is the co-pi of this study and involved in the design and interpretation of the kinetic modeling as well in writing the manuscript	is the co-pi of this study and involved in the design and interpretation of the kinetic modeling as well in writing the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3155201	21841971	WL	2	assisted in conducting the animal studies, gave valuable input on animal handling, performed the image reconstructions, and reviewed the manuscript	assisted in conducting the animal studies, gave valuable input on animal handling, performed the image reconstructions, and reviewed the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Investigation|Visualization|Writing - Review & Editing	YES
3155201	21841971	XZ	2	helped perform the animal studies, gave valuable input on the biological aspects and reviewed the paper	helped perform the animal studies, gave valuable input on the biological aspects and reviewed the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5115960	27686464	all authors	1	Study concept and design	Study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5705166	28872281	A.C.G.	2	contributed to interpretation of data and manuscript revisions	contributed to interpretation of data and manuscript revisions	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
5705166	28872281	A.K.	2	contributed to data analysis and revising the manuscript	contributed to data analysis and revising the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5705166	28872281	C.D.R.	2	contributed to study conception, interpretation of data and revising the manuscript	contributed to study conception, interpretation of data and revising the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Resources|Writing - Review & Editing	YES
5705166	28872281	E.H.	2	contributed to data analysis and revising the manuscript	contributed to data analysis and revising the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5705166	28872281	R.C.	2	contributed to study conception, interpretation of data and manuscript revisions	contributed to study conception, interpretation of data and manuscript revisions	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Resources|Writing - Review & Editing	YES
5705166	28872281	R.S.	2	contributed to study conception and revising the manuscript	contributed to study conception and revising the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5705166	28872281	S.A.H.	2	conceived the study and drafted the manuscript	conceived the study and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
1762352	17183691	DB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Collected and managed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762352	17183691	DB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Collected and managed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762352	17183691	DB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Collected and managed the data	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762352	17183691	DB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Collected and managed the data	Collected and managed the data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
1762352	17183691	JP	PLoS5	Wrote the paper|Collected and managed the data	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762352	17183691	JP	PLoS5	Wrote the paper|Collected and managed the data	Collected and managed the data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
1762352	17183691	JR	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762352	17183691	JR	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762352	17183691	SM	PLoS5	Analyzed the data|Wrote the paper|Collected and managed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762352	17183691	SM	PLoS5	Analyzed the data|Wrote the paper|Collected and managed the data	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762352	17183691	SM	PLoS5	Analyzed the data|Wrote the paper|Collected and managed the data	Collected and managed the data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
6383282	30791959	All authors	2	were involved in the design of the study|independently analyzed the transcripts, and contributed to the conceptual discussion of the results|contributed to the writing of the manuscript	were involved in the design of the study	Conceived and designed the experiments	Methodology	YES
6383282	30791959	All authors	2	were involved in the design of the study|independently analyzed the transcripts, and contributed to the conceptual discussion of the results|contributed to the writing of the manuscript	independently analyzed the transcripts, and contributed to the conceptual discussion of the results	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
6383282	30791959	All authors	2	were involved in the design of the study|independently analyzed the transcripts, and contributed to the conceptual discussion of the results|contributed to the writing of the manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
6383282	30791959	MS	2	conducted the interviews	conducted the interviews	Performed the experiments	Investigation	YES
3175375	21935501	AM	2	designed the log-linear model, conducted the statistical analysis, wrote the appendix, and assisted in writing the manuscript	designed the log-linear model, conducted the statistical analysis, wrote the appendix, and assisted in writing the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3175375	21935501	JNGB	2	designed the log-linear model, conducted the statistical analysis, wrote the appendix, and assisted in writing the manuscript	designed the log-linear model, conducted the statistical analysis, wrote the appendix, and assisted in writing the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4408088	25905775	ABP	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408088	25905775	ABP	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408088	25905775	ABP	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408088	25905775	ABP	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408088	25905775	AMXS	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408088	25905775	AMXS	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408088	25905775	AMXS	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408088	25905775	AMXS	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408088	25905775	ASB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408088	25905775	ASB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408088	25905775	ASB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408088	25905775	BLP	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408088	25905775	BLP	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408088	25905775	BLP	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408088	25905775	BLP	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408088	25905775	ICP	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408088	25905775	ICP	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408088	25905775	ICP	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408088	25905775	ICP	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408088	25905775	MBM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408088	25905775	MBM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408088	25905775	MBM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408088	25905775	MS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408088	25905775	MS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408088	25905775	MS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408088	25905775	MS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5605625	28966627	HW	PLoS5	Prepared materials	Prepared materials	Performed the experiments	Investigation	YES
5605625	28966627	HY	PLoS5	Prepared materials	Prepared materials	Performed the experiments	Investigation	YES
5605625	28966627	JS	PLoS5	Prepared materials	Prepared materials	Performed the experiments	Investigation	YES
5605625	28966627	JW	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5605625	28966627	MD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Prepared materials|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5605625	28966627	MD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Prepared materials|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
5605625	28966627	MD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Prepared materials|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5605625	28966627	MD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Prepared materials|Wrote the paper	Prepared materials	Performed the experiments	Investigation	YES
5605625	28966627	MD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Prepared materials|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5605625	28966627	XL	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5605625	28966627	XL	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5605625	28966627	XZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5605625	28966627	YG	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5605625	28966627	YQ	PLoS5	Prepared materials	Prepared materials	Performed the experiments	Investigation	YES
5719665	28872269	All authors	PLoS52	contributed to the writing of the manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5719665	28872269	ED	PLoS52	supervised data collection	supervised data collection	Performed the experiments	Investigation|Supervision	YES
5719665	28872269	GMCH	PLoS52	supervised data collection|analysed the data|wrote the first draft of the manuscript	supervised data collection	Performed the experiments	Investigation|Supervision	YES
5719665	28872269	GMCH	PLoS52	supervised data collection|analysed the data|wrote the first draft of the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
5719665	28872269	GMCH	PLoS52	supervised data collection|analysed the data|wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
5719665	28872269	RAF	PLoS52	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5719665	28872269	VS	PLoS52	analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
5129488	27543892	A.C.C.	2	were responsible for acquisition and analysis of data	were responsible for acquisition and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5129488	27543892	A.C.T.	2	were responsible for acquisition and analysis of data	were responsible for acquisition and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5129488	27543892	A.E.L.	2	were responsible for acquisition and analysis of data	were responsible for acquisition and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5129488	27543892	C.J.	2	were responsible for acquisition and analysis of data	were responsible for acquisition and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5129488	27543892	D.N.S.	2	were responsible for acquisition and analysis of data|were responsible for drafting the manuscript or figures	were responsible for acquisition and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5129488	27543892	D.N.S.	2	were responsible for acquisition and analysis of data|were responsible for drafting the manuscript or figures	were responsible for drafting the manuscript or figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5129488	27543892	H.L.	2	were responsible for conception and design of the study|were responsible for acquisition and analysis of data|were responsible for drafting the manuscript or figures	were responsible for conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5129488	27543892	H.L.	2	were responsible for conception and design of the study|were responsible for acquisition and analysis of data|were responsible for drafting the manuscript or figures	were responsible for acquisition and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5129488	27543892	H.L.	2	were responsible for conception and design of the study|were responsible for acquisition and analysis of data|were responsible for drafting the manuscript or figures	were responsible for drafting the manuscript or figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5129488	27543892	H.M.L.	2	were responsible for acquisition and analysis of data	were responsible for acquisition and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5129488	27543892	I.H.	2	were responsible for acquisition and analysis of data|were responsible for drafting the manuscript or figures	were responsible for acquisition and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5129488	27543892	I.H.	2	were responsible for acquisition and analysis of data|were responsible for drafting the manuscript or figures	were responsible for drafting the manuscript or figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5129488	27543892	I.K.	2	were responsible for acquisition and analysis of data	were responsible for acquisition and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5129488	27543892	J.H.	2	were responsible for acquisition and analysis of data	were responsible for acquisition and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5129488	27543892	J.R.L.	2	were responsible for conception and design of the study|were responsible for acquisition and analysis of data|were responsible for drafting the manuscript or figures	were responsible for conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5129488	27543892	J.R.L.	2	were responsible for conception and design of the study|were responsible for acquisition and analysis of data|were responsible for drafting the manuscript or figures	were responsible for acquisition and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5129488	27543892	J.R.L.	2	were responsible for conception and design of the study|were responsible for acquisition and analysis of data|were responsible for drafting the manuscript or figures	were responsible for drafting the manuscript or figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5129488	27543892	J.S.	2	were responsible for acquisition and analysis of data	were responsible for acquisition and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5129488	27543892	K.L.H.	2	were responsible for conception and design of the study|were responsible for acquisition and analysis of data|were responsible for drafting the manuscript or figures	were responsible for conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5129488	27543892	K.L.H.	2	were responsible for conception and design of the study|were responsible for acquisition and analysis of data|were responsible for drafting the manuscript or figures	were responsible for acquisition and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5129488	27543892	K.L.H.	2	were responsible for conception and design of the study|were responsible for acquisition and analysis of data|were responsible for drafting the manuscript or figures	were responsible for drafting the manuscript or figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5129488	27543892	K.N.K.	2	were responsible for acquisition and analysis of data	were responsible for acquisition and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5129488	27543892	L.S.	2	were responsible for acquisition and analysis of data	were responsible for acquisition and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5129488	27543892	L.V.	2	were responsible for acquisition and analysis of data	were responsible for acquisition and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5129488	27543892	M.S.	2	were responsible for acquisition and analysis of data	were responsible for acquisition and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5129488	27543892	R.H.	2	were responsible for acquisition and analysis of data	were responsible for acquisition and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5129488	27543892	R.S.	2	were responsible for acquisition and analysis of data	were responsible for acquisition and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5129488	27543892	S.L.D.	2	were responsible for acquisition and analysis of data	were responsible for acquisition and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5129488	27543892	S.T.	2	were responsible for acquisition and analysis of data	were responsible for acquisition and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5129488	27543892	U.B.S.H.	2	were responsible for acquisition and analysis of data|were responsible for drafting the manuscript or figures	were responsible for acquisition and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5129488	27543892	U.B.S.H.	2	were responsible for acquisition and analysis of data|were responsible for drafting the manuscript or figures	were responsible for drafting the manuscript or figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5129488	27543892	W.A.A.	2	were responsible for acquisition and analysis of data	were responsible for acquisition and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5404283	28438140	DPT	1	Designed study|Performed experiments|Performed analysis|Reviewed draft of paper	Designed study	Conceived and designed the experiments	Methodology	YES
5404283	28438140	DPT	1	Designed study|Performed experiments|Performed analysis|Reviewed draft of paper	Performed experiments	Performed the experiments	Investigation	YES
5404283	28438140	DPT	1	Designed study|Performed experiments|Performed analysis|Reviewed draft of paper	Performed analysis	Performed the experiments	Investigation	YES
5404283	28438140	DPT	1	Designed study|Performed experiments|Performed analysis|Reviewed draft of paper	Reviewed draft of paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5404283	28438140	DTTN	1	Designed study|Performed experiments|Performed analysis|Wrote paper|Reviewed draft of paper	Designed study	Conceived and designed the experiments	Methodology	YES
5404283	28438140	DTTN	1	Designed study|Performed experiments|Performed analysis|Wrote paper|Reviewed draft of paper	Performed experiments	Performed the experiments	Investigation	YES
5404283	28438140	DTTN	1	Designed study|Performed experiments|Performed analysis|Wrote paper|Reviewed draft of paper	Performed analysis	Performed the experiments	Investigation	YES
5404283	28438140	DTTN	1	Designed study|Performed experiments|Performed analysis|Wrote paper|Reviewed draft of paper	Wrote paper	Wrote the paper	Writing - Original Draft	YES
5404283	28438140	DTTN	1	Designed study|Performed experiments|Performed analysis|Wrote paper|Reviewed draft of paper	Reviewed draft of paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5404283	28438140	GET	1	Reviewed draft of paper	Reviewed draft of paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5404283	28438140	MAR	1	Conceived study|Performed analysis|Wrote paper	Conceived study	Conceived and designed the experiments	Conceptualization	YES
5404283	28438140	MAR	1	Conceived study|Performed analysis|Wrote paper	Performed analysis	Performed the experiments	Investigation	YES
5404283	28438140	MAR	1	Conceived study|Performed analysis|Wrote paper	Wrote paper	Wrote the paper	Writing - Original Draft	YES
5404283	28438140	NMN	1	Provided reagents and data for study|Reviewed draft of paper	Provided reagents and data for study	Contributed reagents/materials/analysis tools	Resources	YES
5404283	28438140	NMN	1	Provided reagents and data for study|Reviewed draft of paper	Reviewed draft of paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5404283	28438140	NNMC	1	Performed experiments|Reviewed draft of paper	Performed experiments	Performed the experiments	Investigation	YES
5404283	28438140	NNMC	1	Performed experiments|Reviewed draft of paper	Reviewed draft of paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5404283	28438140	OMS	1	Provided analysis tools|Reviewed draft of paper	Provided analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5404283	28438140	OMS	1	Provided analysis tools|Reviewed draft of paper	Reviewed draft of paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5404283	28438140	PTM	1	Provided reagents and data for study|Reviewed draft of paper	Provided reagents and data for study	Contributed reagents/materials/analysis tools	Resources	YES
5404283	28438140	PTM	1	Provided reagents and data for study|Reviewed draft of paper	Reviewed draft of paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5404283	28438140	PVV	1	Performed experiments|Reviewed draft of paper	Performed experiments	Performed the experiments	Investigation	YES
5404283	28438140	PVV	1	Performed experiments|Reviewed draft of paper	Reviewed draft of paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5404283	28438140	SB	1	Conceived study|Wrote paper	Conceived study	Conceived and designed the experiments	Conceptualization	YES
5404283	28438140	SB	1	Conceived study|Wrote paper	Wrote paper	Wrote the paper	Writing - Original Draft	YES
5404283	28438140	TNTN	1	Performed experiments|Reviewed draft of paper	Performed experiments	Performed the experiments	Investigation	YES
5404283	28438140	TNTN	1	Performed experiments|Reviewed draft of paper	Reviewed draft of paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5404283	28438140	TPTT	1	Provided reagents and data for study|Reviewed draft of paper	Provided reagents and data for study	Contributed reagents/materials/analysis tools	Resources	YES
5404283	28438140	TPTT	1	Provided reagents and data for study|Reviewed draft of paper	Reviewed draft of paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5404283	28438140	TTHC	1	Provided reagents and data for study|Reviewed draft of paper	Provided reagents and data for study	Contributed reagents/materials/analysis tools	Resources	YES
5404283	28438140	TTHC	1	Provided reagents and data for study|Reviewed draft of paper	Reviewed draft of paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5404283	28438140	UKS	1	Performed analysis|Provided analysis tools|Reviewed draft of paper	Performed analysis	Performed the experiments	Investigation	YES
5404283	28438140	UKS	1	Performed analysis|Provided analysis tools|Reviewed draft of paper	Provided analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5404283	28438140	UKS	1	Performed analysis|Provided analysis tools|Reviewed draft of paper	Reviewed draft of paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
1762353	17183725	AM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1762353	17183725	CB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762353	17183725	CB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762353	17183725	CB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762353	17183725	HL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762353	17183725	HL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762353	17183725	HL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762353	17183725	HL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762353	17183725	HL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762353	17183725	MG	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762353	17183725	SS	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762353	17183725	SS	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762353	17183725	VD	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1762353	17183725	VD	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762353	17183725	WF	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
3203019	22039577	BE	4	brain metabolism studies were carried out by	brain metabolism studies were carried out by	Performed the experiments	Investigation	YES
3203019	22039577	CC	4	microPET data analysis was carried out by	microPET data analysis was carried out by	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3203019	22039577	JM	4	brain metabolism studies were carried out by|The study and all data acquired was coordinated and reviewed by	brain metabolism studies were carried out by	Performed the experiments	Investigation	YES
3203019	22039577	JM	4	brain metabolism studies were carried out by|The study and all data acquired was coordinated and reviewed by	The study and all data acquired was coordinated and reviewed by	-	Project administration	YES
3203019	22039577	MLP	4	synthesis and metabolite analysis were carried out by	synthesis and metabolite analysis were carried out by	Performed the experiments	Investigation	YES
3203019	22039577	PP	4	autoradiographic studies and analysis were carried out by	autoradiographic studies and analysis were carried out by	Performed the experiments	Investigation	YES
3203019	22039577	RK	4	autoradiographic studies and analysis were carried out by	autoradiographic studies and analysis were carried out by	Performed the experiments	Investigation	YES
3203019	22039577	SKP	4	synthesis and metabolite analysis were carried out by	synthesis and metabolite analysis were carried out by	Performed the experiments	Investigation	YES
5220169	28144366	Antoine Delage	2	participated in study planning, execution, data analysis, editing of the manuscript and was co-primary investigator of the study	participated in study planning, execution, data analysis, editing of the manuscript and was co-primary investigator of the study	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Review & Editing	YES
5220169	28144366	Krystelle Godbout	2	participated in study planning, data analysis and was the primary author of the manuscript	participated in study planning, data analysis and was the primary author of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5220169	28144366	Mathieu Simon	2	participated in study planning, execution, and editing of the manuscript	participated in study planning, execution, and editing of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
5220169	28144366	Noel Lampron	2	participated in study planning, execution, and editing of the manuscript	participated in study planning, execution, and editing of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
5220169	28144366	Simon Martel	2	participated in study planning, execution, editing of the manuscript and was co-primary investigator of the study	participated in study planning, execution, editing of the manuscript and was co-primary investigator of the study	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
5719718	28530036	AA	2	contributed intellectual content	contributed intellectual content	-	-	NO
5719718	28530036	ALS	2	conceived of the review and conducted background research|drafted the manuscript and all authors critically reviewed and approved of the manuscript	conceived of the review and conducted background research	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5719718	28530036	ALS	2	conceived of the review and conducted background research|drafted the manuscript and all authors critically reviewed and approved of the manuscript	drafted the manuscript and all authors critically reviewed and approved of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5719718	28530036	MD	2	conceived of the review and conducted background research	conceived of the review and conducted background research	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5719718	28530036	MM	2	provided additional unaids data and contributed to analysis and interpretation of the data	provided additional unaids data and contributed to analysis and interpretation of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5129566	27351142	A.J.	1	Drafting a significant portion of the manuscript or figures	Drafting a significant portion of the manuscript or figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5129566	27351142	C.B.	1	Drafting a significant portion of the manuscript or figures	Drafting a significant portion of the manuscript or figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5129566	27351142	E.B.	1	Conception and design of the study|Drafting a significant portion of the manuscript or figures	Conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5129566	27351142	E.B.	1	Conception and design of the study|Drafting a significant portion of the manuscript or figures	Drafting a significant portion of the manuscript or figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5129566	27351142	K.D.	1	Conception and design of the study|Drafting a significant portion of the manuscript or figures	Conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5129566	27351142	K.D.	1	Conception and design of the study|Drafting a significant portion of the manuscript or figures	Drafting a significant portion of the manuscript or figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5129566	27351142	K.H.	1	Conception and design of the study|Drafting a significant portion of the manuscript or figures	Conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5129566	27351142	K.H.	1	Conception and design of the study|Drafting a significant portion of the manuscript or figures	Drafting a significant portion of the manuscript or figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5129566	27351142	L.A.G.	1	Conception and design of the study|Drafting a significant portion of the manuscript or figures	Conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5129566	27351142	L.A.G.	1	Conception and design of the study|Drafting a significant portion of the manuscript or figures	Drafting a significant portion of the manuscript or figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5129566	27351142	R.H.	1	Conception and design of the study|Drafting a significant portion of the manuscript or figures	Conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5129566	27351142	R.H.	1	Conception and design of the study|Drafting a significant portion of the manuscript or figures	Drafting a significant portion of the manuscript or figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5129566	27351142	T.K.	1	Conception and design of the study|Drafting a significant portion of the manuscript or figures	Conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5129566	27351142	T.K.	1	Conception and design of the study|Drafting a significant portion of the manuscript or figures	Drafting a significant portion of the manuscript or figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5129566	27351142	all authors	1	Acquisition and analysis of data	Acquisition and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6391805	30813945	ACP	2	conceived and developed the ideas for this manuscript	conceived and developed the ideas for this manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
6391805	30813945	ARM	2	provided substantial inputs	provided substantial inputs	-	-	NO
6391805	30813945	DJS	2	conceived and developed the ideas for this manuscript|provided substantial inputs	conceived and developed the ideas for this manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
6391805	30813945	DJS	2	conceived and developed the ideas for this manuscript|provided substantial inputs	provided substantial inputs	-	-	NO
6391805	30813945	JDV	2	provided substantial inputs	provided substantial inputs	-	-	NO
6391805	30813945	SD	2	provided substantial inputs	provided substantial inputs	-	-	NO
6391805	30813945	all authors	2	reviewed and approved the final version	reviewed and approved the final version	-	-	NO
1762354	17183632	AV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Enrolled patients|Approved final version of the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762354	17183632	AV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Enrolled patients|Approved final version of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
1762354	17183632	AV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Enrolled patients|Approved final version of the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762354	17183632	AV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Enrolled patients|Approved final version of the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762354	17183632	AV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Enrolled patients|Approved final version of the manuscript	Enrolled patients	Performed the experiments	Investigation	YES
1762354	17183632	AV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Enrolled patients|Approved final version of the manuscript	Approved final version of the manuscript	-	-	NO
1762354	17183632	DC	PLoS5	Conceived and designed the experiments|Analyzed the data|Approved final version of the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762354	17183632	DC	PLoS5	Conceived and designed the experiments|Analyzed the data|Approved final version of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
1762354	17183632	DC	PLoS5	Conceived and designed the experiments|Analyzed the data|Approved final version of the manuscript	Approved final version of the manuscript	-	-	NO
1762354	17183632	EdA	PLoS5	Contributed reagents/materials/analysis tools|Enrolled patients|Approved final version of the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762354	17183632	EdA	PLoS5	Contributed reagents/materials/analysis tools|Enrolled patients|Approved final version of the manuscript	Enrolled patients	Performed the experiments	Investigation	YES
1762354	17183632	EdA	PLoS5	Contributed reagents/materials/analysis tools|Enrolled patients|Approved final version of the manuscript	Approved final version of the manuscript	-	-	NO
1762354	17183632	LV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Supervised lab work|Approved final version of the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762354	17183632	LV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Supervised lab work|Approved final version of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
1762354	17183632	LV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Supervised lab work|Approved final version of the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762354	17183632	LV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Supervised lab work|Approved final version of the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762354	17183632	LV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Supervised lab work|Approved final version of the manuscript	Supervised lab work	Performed the experiments	Investigation|Supervision	YES
1762354	17183632	LV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Supervised lab work|Approved final version of the manuscript	Approved final version of the manuscript	-	-	NO
1762354	17183632	PS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Enrolled patients	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762354	17183632	PS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Enrolled patients	Performed the experiments	Performed the experiments	Investigation	YES
1762354	17183632	PS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Enrolled patients	Analyzed the data	Analyzed the data	Formal analysis	YES
1762354	17183632	PS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Enrolled patients	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762354	17183632	PS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Enrolled patients	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762354	17183632	PS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Enrolled patients	Enrolled patients	Performed the experiments	Investigation	YES
1762354	17183632	VM	PLoS5	Contributed reagents/materials/analysis tools|Enrolled patients|Approved final version of the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762354	17183632	VM	PLoS5	Contributed reagents/materials/analysis tools|Enrolled patients|Approved final version of the manuscript	Enrolled patients	Performed the experiments	Investigation	YES
1762354	17183632	VM	PLoS5	Contributed reagents/materials/analysis tools|Enrolled patients|Approved final version of the manuscript	Approved final version of the manuscript	-	-	NO
4408089	25905473	AvdF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408089	25905473	AvdF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408089	25905473	AvdF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408089	25905473	AvdF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408089	25905473	AvdF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408089	25905473	DD	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4408089	25905473	DD	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4408089	25905473	DRL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408089	25905473	DRL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408089	25905473	DRL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408089	25905473	HJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408089	25905473	HJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408089	25905473	HJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408089	25905473	KC	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4408089	25905473	KC	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4408089	25905473	KC	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408089	25905473	SPW	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4408089	25905473	SPW	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4408089	25905473	ST	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4408089	25905473	ST	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4408089	25905473	ST	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408089	25905473	TL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4408089	25905473	TL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4408089	25905473	TL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408089	25905473	ZL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4408089	25905473	ZL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4408089	25905473	ZL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5605630	28966623	BH	2	performed the greenhouse experiments and analyzed the data, with the	performed the greenhouse experiments and analyzed the data, with the	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5605630	28966623	BX	2	helped with the designed the experiments with the|helped with the with the|helped with the and revised and approved the final manuscript with the	helped with the designed the experiments with the	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5605630	28966623	BX	2	helped with the designed the experiments with the|helped with the with the|helped with the and revised and approved the final manuscript with the	helped with the with the	-	-	NO
5605630	28966623	BX	2	helped with the designed the experiments with the|helped with the with the|helped with the and revised and approved the final manuscript with the	helped with the and revised and approved the final manuscript with the	Wrote the paper	Writing - Review & Editing	YES
5605630	28966623	SZ	2	designed the experiments with the|performed the greenhouse experiments and analyzed the data, with the|wrote the manuscript, and revised and approved the final manuscript with the	designed the experiments with the	Conceived and designed the experiments	Methodology	YES
5605630	28966623	SZ	2	designed the experiments with the|performed the greenhouse experiments and analyzed the data, with the|wrote the manuscript, and revised and approved the final manuscript with the	performed the greenhouse experiments and analyzed the data, with the	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5605630	28966623	SZ	2	designed the experiments with the|performed the greenhouse experiments and analyzed the data, with the|wrote the manuscript, and revised and approved the final manuscript with the	wrote the manuscript, and revised and approved the final manuscript with the	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5605630	28966623	WJ	2	designed the experiments with the	designed the experiments with the	Conceived and designed the experiments	Methodology	YES
5605630	28966623	YG	2	performed the greenhouse experiments and analyzed the data, with the|wrote the manuscript, and revised and approved the final manuscript with the	performed the greenhouse experiments and analyzed the data, with the	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5605630	28966623	YG	2	performed the greenhouse experiments and analyzed the data, with the|wrote the manuscript, and revised and approved the final manuscript with the	wrote the manuscript, and revised and approved the final manuscript with the	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5404671	28438123	FL	2	performed experiments and contributed to data analysis and validation	performed experiments and contributed to data analysis and validation	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Validation	YES
5404671	28438123	JLG	2	performed experiments and contributed to data analysis and validation	performed experiments and contributed to data analysis and validation	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Validation	YES
5404671	28438123	LPX	2	helped to revise the manuscript	helped to revise the manuscript	Wrote the paper	Writing - Review & Editing	YES
5404671	28438123	NH	2	performed experiments and contributed to data analysis and validation	performed experiments and contributed to data analysis and validation	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Validation	YES
5404671	28438123	QBW	2	performed experiments and contributed to data analysis and validation	performed experiments and contributed to data analysis and validation	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Validation	YES
5404671	28438123	WA	2	performed experiments and contributed to data analysis and validation	performed experiments and contributed to data analysis and validation	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Validation	YES
5404671	28438123	WHS	2	performed experiments and contributed to data analysis and validation	performed experiments and contributed to data analysis and validation	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Validation	YES
5404671	28438123	YCS	2	conceived, designed and initiated the project|drafted the manuscript	conceived, designed and initiated the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5404671	28438123	YCS	2	conceived, designed and initiated the project|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5404671	28438123	YXQ	2	conceived, designed and initiated the project|drafted the manuscript|helped to revise the manuscript	conceived, designed and initiated the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5404671	28438123	YXQ	2	conceived, designed and initiated the project|drafted the manuscript|helped to revise the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5404671	28438123	YXQ	2	conceived, designed and initiated the project|drafted the manuscript|helped to revise the manuscript	helped to revise the manuscript	Wrote the paper	Writing - Review & Editing	YES
5404671	28438123	YYZ	2	conceived, designed and initiated the project|prepared materials|performed experiments and contributed to data analysis and validation	conceived, designed and initiated the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5404671	28438123	YYZ	2	conceived, designed and initiated the project|prepared materials|performed experiments and contributed to data analysis and validation	prepared materials	Performed the experiments	Investigation	YES
5404671	28438123	YYZ	2	conceived, designed and initiated the project|prepared materials|performed experiments and contributed to data analysis and validation	performed experiments and contributed to data analysis and validation	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Validation	YES
3250963	22214201	BW	7	carried out the binding assays	carried out the binding assays	Performed the experiments	Investigation	YES
3250963	22214201	DC	7	carried out the synthesis of the peptides and participated in the manuscript draft	carried out the synthesis of the peptides and participated in the manuscript draft	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3250963	22214201	JCR	7	participated in the conception, design and coordination of the study, and in the interpretation of the data. He reviewed the draft manuscript	participated in the conception, design and coordination of the study, and in the interpretation of the data. He reviewed the draft manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Project administration|Writing - Original Draft|Writing - Review & Editing	YES
3250963	22214201	JE	7	carried out the synthesis of the peptides and reviewed the chemistry data	carried out the synthesis of the peptides and reviewed the chemistry data	Performed the experiments	Investigation	YES
3250963	22214201	JER	7	participated in the conception, design and coordination of the study, and reviewed the chemistry data	participated in the conception, design and coordination of the study, and reviewed the chemistry data	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
3250963	22214201	RC	7	carried out the functional assays	carried out the functional assays	Performed the experiments	Investigation	YES
4296984	25992084	P. Thulasidas	7	study design, data collection, data interpretation, analysis	study design, data collection, data interpretation, analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
4296984	25992084	V. Venkatraman	7	data collection, manuscript, analysis	data collection, manuscript, analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6446322	30944009	EAM	2	conceived and drafted the paper	conceived and drafted the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
6446322	30944009	JGK	2	contributed to the concept, edited the paper and provided a number of illustrations and examples	contributed to the concept, edited the paper and provided a number of illustrations and examples	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Visualization|Writing - Review & Editing	YES
4408090	25905898	JQG	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4408090	25905898	JQG	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4408090	25905898	XFP	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408090	25905898	XFP	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408090	25905898	XFP	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408090	25905898	ZYS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408090	25905898	ZYS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
3250964	22214432	HH	2	carried out the autoradiography studies including interpretation and analysis of these data, and contributed to performing experiments and writing of parts of the manuscript	carried out the autoradiography studies including interpretation and analysis of these data, and contributed to performing experiments and writing of parts of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3250964	22214432	JB	2	performed radiolabeling and contributed in manuscript writing	performed radiolabeling and contributed in manuscript writing	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3250964	22214432	JD	2	contributed to the study design, interpretation and analyses of data, writing the manuscript as well as performing experiments and dosimetry calculations	contributed to the study design, interpretation and analyses of data, writing the manuscript as well as performing experiments and dosimetry calculations	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
3250964	22214432	JN	2	carried out histopathological studies of slides	carried out histopathological studies of slides	Performed the experiments	Investigation	YES
3250964	22214432	NA	2	designed and performed the invivo studies and carried out interpretation and analysis of data including dosimetry calculation and writing of manuscript|carried out histopathological studies of slides	designed and performed the invivo studies and carried out interpretation and analysis of data including dosimetry calculation and writing of manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
3250964	22214432	NA	2	designed and performed the invivo studies and carried out interpretation and analysis of data including dosimetry calculation and writing of manuscript|carried out histopathological studies of slides	carried out histopathological studies of slides	Performed the experiments	Investigation	YES
3250964	22214432	OSB	2	contributed to the study design, interpretation and analyses of data as well as writing of the manuscript	contributed to the study design, interpretation and analyses of data as well as writing of the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Original Draft	YES
1762355	17183672	BG	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762355	17183672	BG	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762355	17183672	CP	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762355	17183672	DA	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762355	17183672	DA	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762355	17183672	EP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1762355	17183672	FP	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762355	17183672	FP	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1762355	17183672	FP	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762355	17183672	JB	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762355	17183672	JB	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762355	17183672	LT	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762355	17183672	LT	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762355	17183672	MP	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762355	17183672	MP	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762355	17183672	ON	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762355	17183672	ON	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762355	17183672	ON	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762355	17183672	ON	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762355	17183672	PF	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762355	17183672	RH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762355	17183672	RH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1762355	17183672	RH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1762355	17183672	RH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762355	17183672	YB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5804015	29412520	BL	2	contributed to editing and critical revision of the manuscript for important intellectual content	contributed to editing and critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5804015	29412520	BT	2	contributed to editing and critical revision of the manuscript for important intellectual content	contributed to editing and critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5804015	29412520	CC	2	contributed to editing and critical revision of the manuscript for important intellectual content	contributed to editing and critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5804015	29412520	CT	2	contributed to editing and critical revision of the manuscript for important intellectual content	contributed to editing and critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5804015	29412520	JB	2	contributed to editing and critical revision of the manuscript for important intellectual content	contributed to editing and critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5804015	29412520	JC	2	conceived and designed the study|performed the statistical analyses and data interpretation|drafted the manuscript|contributed to editing and critical revision of the manuscript for important intellectual content	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5804015	29412520	JC	2	conceived and designed the study|performed the statistical analyses and data interpretation|drafted the manuscript|contributed to editing and critical revision of the manuscript for important intellectual content	performed the statistical analyses and data interpretation	Analyzed the data	Formal analysis	YES
5804015	29412520	JC	2	conceived and designed the study|performed the statistical analyses and data interpretation|drafted the manuscript|contributed to editing and critical revision of the manuscript for important intellectual content	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5804015	29412520	JC	2	conceived and designed the study|performed the statistical analyses and data interpretation|drafted the manuscript|contributed to editing and critical revision of the manuscript for important intellectual content	contributed to editing and critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5804015	29412520	JGB	2	contributed to editing and critical revision of the manuscript for important intellectual content	contributed to editing and critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5804015	29412520	JPR	2	conceived and designed the study|were involved in the data acquisition|performed the statistical analyses and data interpretation|drafted the manuscript|also obtained funding and administrative support for the study|contributed to editing and critical revision of the manuscript for important intellectual content	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5804015	29412520	JPR	2	conceived and designed the study|were involved in the data acquisition|performed the statistical analyses and data interpretation|drafted the manuscript|also obtained funding and administrative support for the study|contributed to editing and critical revision of the manuscript for important intellectual content	were involved in the data acquisition	Performed the experiments	Investigation	YES
5804015	29412520	JPR	2	conceived and designed the study|were involved in the data acquisition|performed the statistical analyses and data interpretation|drafted the manuscript|also obtained funding and administrative support for the study|contributed to editing and critical revision of the manuscript for important intellectual content	performed the statistical analyses and data interpretation	Analyzed the data	Formal analysis	YES
5804015	29412520	JPR	2	conceived and designed the study|were involved in the data acquisition|performed the statistical analyses and data interpretation|drafted the manuscript|also obtained funding and administrative support for the study|contributed to editing and critical revision of the manuscript for important intellectual content	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5804015	29412520	JPR	2	conceived and designed the study|were involved in the data acquisition|performed the statistical analyses and data interpretation|drafted the manuscript|also obtained funding and administrative support for the study|contributed to editing and critical revision of the manuscript for important intellectual content	also obtained funding and administrative support for the study	-	Funding acquisition|Project administration	YES
5804015	29412520	JPR	2	conceived and designed the study|were involved in the data acquisition|performed the statistical analyses and data interpretation|drafted the manuscript|also obtained funding and administrative support for the study|contributed to editing and critical revision of the manuscript for important intellectual content	contributed to editing and critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5804015	29412520	JS	2	contributed to editing and critical revision of the manuscript for important intellectual content	contributed to editing and critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5804015	29412520	PC	2	contributed to editing and critical revision of the manuscript for important intellectual content	contributed to editing and critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5804015	29412520	RL	2	contributed to editing and critical revision of the manuscript for important intellectual content	contributed to editing and critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5804015	29412520	RP	2	contributed to editing and critical revision of the manuscript for important intellectual content	contributed to editing and critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5804015	29412520	RT	2	contributed to editing and critical revision of the manuscript for important intellectual content	contributed to editing and critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5804015	29412520	TL	2	contributed to editing and critical revision of the manuscript for important intellectual content	contributed to editing and critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5804015	29412520	VM	2	conceived and designed the study|were involved in the data acquisition|performed the statistical analyses and data interpretation|drafted the manuscript|contributed to editing and critical revision of the manuscript for important intellectual content	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5804015	29412520	VM	2	conceived and designed the study|were involved in the data acquisition|performed the statistical analyses and data interpretation|drafted the manuscript|contributed to editing and critical revision of the manuscript for important intellectual content	were involved in the data acquisition	Performed the experiments	Investigation	YES
5804015	29412520	VM	2	conceived and designed the study|were involved in the data acquisition|performed the statistical analyses and data interpretation|drafted the manuscript|contributed to editing and critical revision of the manuscript for important intellectual content	performed the statistical analyses and data interpretation	Analyzed the data	Formal analysis	YES
5804015	29412520	VM	2	conceived and designed the study|were involved in the data acquisition|performed the statistical analyses and data interpretation|drafted the manuscript|contributed to editing and critical revision of the manuscript for important intellectual content	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5804015	29412520	VM	2	conceived and designed the study|were involved in the data acquisition|performed the statistical analyses and data interpretation|drafted the manuscript|contributed to editing and critical revision of the manuscript for important intellectual content	contributed to editing and critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5804015	29412520	WC	2	contributed to editing and critical revision of the manuscript for important intellectual content	contributed to editing and critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
6458617	30975177	JB	2	was the sole contributor in writing the manuscript	was the sole contributor in writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5605631	28966625	AR	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5605631	28966625	AS	PLoS52	analyzed the data|with some contributions from all the other authors	analyzed the data	Analyzed the data	Formal analysis	YES
5605631	28966625	AS	PLoS52	analyzed the data|with some contributions from all the other authors	with some contributions from all the other authors	-	-	NO
5605631	28966625	BN	PLoS52	collected litter samples, produced the biochar, performed the experiments, and make chemical analyses	collected litter samples, produced the biochar, performed the experiments, and make chemical analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5605631	28966625	FI	PLoS52	collected litter samples, produced the biochar, performed the experiments, and make chemical analyses	collected litter samples, produced the biochar, performed the experiments, and make chemical analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5605631	28966625	FS	PLoS52	with some contributions from all the other authors	with some contributions from all the other authors	-	-	NO
5605631	28966625	GB	PLoS52	conceived the project|analyzed the data|with some contributions from all the other authors	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5605631	28966625	GB	PLoS52	conceived the project|analyzed the data|with some contributions from all the other authors	analyzed the data	Analyzed the data	Formal analysis	YES
5605631	28966625	GB	PLoS52	conceived the project|analyzed the data|with some contributions from all the other authors	with some contributions from all the other authors	-	-	NO
5605631	28966625	GC	PLoS52	collected litter samples, produced the biochar, performed the experiments, and make chemical analyses	collected litter samples, produced the biochar, performed the experiments, and make chemical analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5605631	28966625	NL	PLoS52	collected litter samples, produced the biochar, performed the experiments, and make chemical analyses	collected litter samples, produced the biochar, performed the experiments, and make chemical analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5215570	27804148	A.A.	2	were responsible for acquisition and analysis of data|contributed equally to this work	were responsible for acquisition and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5215570	27804148	A.A.	2	were responsible for acquisition and analysis of data|contributed equally to this work	contributed equally to this work	-	-	NO
5215570	27804148	A.V.D.	2	were responsible for acquisition and analysis of data	were responsible for acquisition and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5215570	27804148	J.D.C.	2	were responsible for acquisition and analysis of data	were responsible for acquisition and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5215570	27804148	J.O.	2	were responsible for acquisition and analysis of data	were responsible for acquisition and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5215570	27804148	K.V.R.R.	2	were responsible for acquisition and analysis of data	were responsible for acquisition and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5215570	27804148	M.B.	2	were responsible for acquisition and analysis of data	were responsible for acquisition and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5215570	27804148	M.E.B.	2	were responsible for acquisition and analysis of data|contributed equally to this work	were responsible for acquisition and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5215570	27804148	M.E.B.	2	were responsible for acquisition and analysis of data|contributed equally to this work	contributed equally to this work	-	-	NO
5215570	27804148	R.F.	2	were responsible for acquisition and analysis of data	were responsible for acquisition and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5215570	27804148	T.K.	2	was responsible for study conception and design and wrote the manuscript	was responsible for study conception and design and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
5405463	28446171	BM	PLoS52	conceived the study|participated in the design of the study|performed the experiments|interpreted the data|drafted the paper	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5405463	28446171	BM	PLoS52	conceived the study|participated in the design of the study|performed the experiments|interpreted the data|drafted the paper	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
5405463	28446171	BM	PLoS52	conceived the study|participated in the design of the study|performed the experiments|interpreted the data|drafted the paper	performed the experiments	Performed the experiments	Investigation	YES
5405463	28446171	BM	PLoS52	conceived the study|participated in the design of the study|performed the experiments|interpreted the data|drafted the paper	interpreted the data	Analyzed the data	Formal analysis	YES
5405463	28446171	BM	PLoS52	conceived the study|participated in the design of the study|performed the experiments|interpreted the data|drafted the paper	drafted the paper	Wrote the paper	Writing - Original Draft	YES
5405463	28446171	DE	PLoS52	sequenced the transcriptome	sequenced the transcriptome	Performed the experiments	Investigation	YES
5405463	28446171	HS	PLoS52	participated in the design of the study	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
5405463	28446171	JK	PLoS52	conceived the study|participated in the design of the study|interpreted the data|drafted the paper	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5405463	28446171	JK	PLoS52	conceived the study|participated in the design of the study|interpreted the data|drafted the paper	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
5405463	28446171	JK	PLoS52	conceived the study|participated in the design of the study|interpreted the data|drafted the paper	interpreted the data	Analyzed the data	Formal analysis	YES
5405463	28446171	JK	PLoS52	conceived the study|participated in the design of the study|interpreted the data|drafted the paper	drafted the paper	Wrote the paper	Writing - Original Draft	YES
5405463	28446171	JMG	PLoS52	performed the statistical and bioinformatic analyses|interpreted the data|drafted the paper	performed the statistical and bioinformatic analyses	Analyzed the data	Formal analysis	YES
5405463	28446171	JMG	PLoS52	performed the statistical and bioinformatic analyses|interpreted the data|drafted the paper	interpreted the data	Analyzed the data	Formal analysis	YES
5405463	28446171	JMG	PLoS52	performed the statistical and bioinformatic analyses|interpreted the data|drafted the paper	drafted the paper	Wrote the paper	Writing - Original Draft	YES
5405463	28446171	PR	PLoS52	participated in the design of the study|sequenced the transcriptome	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
5405463	28446171	PR	PLoS52	participated in the design of the study|sequenced the transcriptome	sequenced the transcriptome	Performed the experiments	Investigation	YES
5405463	28446171	RP	PLoS52	conceived the study|participated in the design of the study|interpreted the data|drafted the paper	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5405463	28446171	RP	PLoS52	conceived the study|participated in the design of the study|interpreted the data|drafted the paper	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
5405463	28446171	RP	PLoS52	conceived the study|participated in the design of the study|interpreted the data|drafted the paper	interpreted the data	Analyzed the data	Formal analysis	YES
5405463	28446171	RP	PLoS52	conceived the study|participated in the design of the study|interpreted the data|drafted the paper	drafted the paper	Wrote the paper	Writing - Original Draft	YES
5405463	28446171	SB	PLoS52	participated in the design of the study	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
4408091	25905630	AH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4408091	25905630	DZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408091	25905630	DZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408091	25905630	DZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408091	25905630	DZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408091	25905630	EP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4408091	25905630	HML	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408091	25905630	HML	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408091	25905630	HML	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408091	25905630	JC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4408091	25905630	JD	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4408091	25905630	ML	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408091	25905630	ML	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408091	25905630	ML	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408091	25905630	SJ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4612445	26298350	AB	2	helped devise the project, participated in the data collection and validation committee, and read and approved the final manuscript	helped devise the project, participated in the data collection and validation committee, and read and approved the final manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Validation|Writing - Review & Editing	YES
4612445	26298350	CCP	2	advised on the statistical design of the study, compiled the data, conducted the data analysis and co-authored the manuscript	advised on the statistical design of the study, compiled the data, conducted the data analysis and co-authored the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Data curation|Formal analysis|Methodology|Writing - Original Draft	YES
4612445	26298350	CaRE	2	read and approved the final manuscript|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4612445	26298350	CaRE	2	read and approved the final manuscript|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4612445	26298350	GL	2	helped devise the project, was responsible for the glasgow biomarker assays, and read and approved the final manuscript	helped devise the project, was responsible for the glasgow biomarker assays, and read and approved the final manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4612445	26298350	IY	2	helped devise the project, had overall responsibility for the belfast assays, and read and approved the final manuscript	helped devise the project, had overall responsibility for the belfast assays, and read and approved the final manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4612445	26298350	JG	2	helped devise the project, and read and approved the final manuscript	helped devise the project, and read and approved the final manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Review & Editing	YES
4612445	26298350	LH	2	was responsible for collecting and compiling the outcome data and convening the validation committee, and he read and approved the final manuscript	was responsible for collecting and compiling the outcome data and convening the validation committee, and he read and approved the final manuscript	Performed the experiments|Wrote the paper	Investigation|Validation|Writing - Review & Editing	YES
4612445	26298350	YB-S	2	helped devise the project, assisted in the data collection, validated the clinical events, read and approved the final manuscript	helped devise the project, assisted in the data collection, validated the clinical events, read and approved the final manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Validation|Writing - Review & Editing	YES
1762356	17183708	CC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762356	17183708	CC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762356	17183708	CC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762356	17183708	KG	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762356	17183708	KG	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1762356	17183708	SR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762356	17183708	SR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762356	17183708	SR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762356	17183708	SR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762356	17183708	SR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3250971	22214227	AL	2	provided vital scientific input and edited the manuscript	provided vital scientific input and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
3250971	22214227	AP	2	provided vital scientific input and edited the manuscript	provided vital scientific input and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
3250971	22214227	AS	2	provided vital scientific input and edited the manuscript	provided vital scientific input and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
3250971	22214227	CL	2	performed and were responsible for fdg production	performed and were responsible for fdg production	Performed the experiments	Investigation	YES
3250971	22214227	DG	2	performed and were responsible for fdg production	performed and were responsible for fdg production	Performed the experiments	Investigation	YES
3250971	22214227	FG	2	performed and were responsible for fdg production	performed and were responsible for fdg production	Performed the experiments	Investigation	YES
3250971	22214227	GW	2	performed the data analysis	performed the data analysis	Analyzed the data	Formal analysis	YES
3250971	22214227	JA	2	performed and were responsible for fdg production	performed and were responsible for fdg production	Performed the experiments	Investigation	YES
3250971	22214227	MB	2	performed the data analysis	performed the data analysis	Analyzed the data	Formal analysis	YES
3250971	22214227	XL	2	provided vital scientific input and edited the manuscript	provided vital scientific input and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5808101	29430854	AGV	2	conceptualized and designed the study|collected darunavir plasma levels|collected, assembled the data and managed the database|analysed and interpreted the data|drafted the article	conceptualized and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5808101	29430854	AGV	2	conceptualized and designed the study|collected darunavir plasma levels|collected, assembled the data and managed the database|analysed and interpreted the data|drafted the article	collected darunavir plasma levels	Performed the experiments	Investigation	YES
5808101	29430854	AGV	2	conceptualized and designed the study|collected darunavir plasma levels|collected, assembled the data and managed the database|analysed and interpreted the data|drafted the article	collected, assembled the data and managed the database	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Investigation|Software	YES
5808101	29430854	AGV	2	conceptualized and designed the study|collected darunavir plasma levels|collected, assembled the data and managed the database|analysed and interpreted the data|drafted the article	analysed and interpreted the data	Analyzed the data	Formal analysis	YES
5808101	29430854	AGV	2	conceptualized and designed the study|collected darunavir plasma levels|collected, assembled the data and managed the database|analysed and interpreted the data|drafted the article	drafted the article	Wrote the paper	Writing - Original Draft	YES
5808101	29430854	LFLC	2	conceptualized and designed the study|obtaining funding for the study|contributed to provision of study materials or subjects|analysed and interpreted the data|drafted the article	conceptualized and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5808101	29430854	LFLC	2	conceptualized and designed the study|obtaining funding for the study|contributed to provision of study materials or subjects|analysed and interpreted the data|drafted the article	obtaining funding for the study	-	Funding acquisition	YES
5808101	29430854	LFLC	2	conceptualized and designed the study|obtaining funding for the study|contributed to provision of study materials or subjects|analysed and interpreted the data|drafted the article	contributed to provision of study materials or subjects	Contributed reagents/materials/analysis tools	Resources	YES
5808101	29430854	LFLC	2	conceptualized and designed the study|obtaining funding for the study|contributed to provision of study materials or subjects|analysed and interpreted the data|drafted the article	analysed and interpreted the data	Analyzed the data	Formal analysis	YES
5808101	29430854	LFLC	2	conceptualized and designed the study|obtaining funding for the study|contributed to provision of study materials or subjects|analysed and interpreted the data|drafted the article	drafted the article	Wrote the paper	Writing - Original Draft	YES
5808101	29430854	MTR	2	conceptualized and designed the study|collected, assembled the data and managed the database|analysed and interpreted the data|drafted the article	conceptualized and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5808101	29430854	MTR	2	conceptualized and designed the study|collected, assembled the data and managed the database|analysed and interpreted the data|drafted the article	collected, assembled the data and managed the database	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Investigation|Software	YES
5808101	29430854	MTR	2	conceptualized and designed the study|collected, assembled the data and managed the database|analysed and interpreted the data|drafted the article	analysed and interpreted the data	Analyzed the data	Formal analysis	YES
5808101	29430854	MTR	2	conceptualized and designed the study|collected, assembled the data and managed the database|analysed and interpreted the data|drafted the article	drafted the article	Wrote the paper	Writing - Original Draft	YES
5808101	29430854	NE	2	contributed to provision of study materials or subjects|critically reviewed the article for important intellectual content	contributed to provision of study materials or subjects	Contributed reagents/materials/analysis tools	Resources	YES
5808101	29430854	NE	2	contributed to provision of study materials or subjects|critically reviewed the article for important intellectual content	critically reviewed the article for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5808101	29430854	PV	2	contributed to provision of study materials or subjects|critically reviewed the article for important intellectual content	contributed to provision of study materials or subjects	Contributed reagents/materials/analysis tools	Resources	YES
5808101	29430854	PV	2	contributed to provision of study materials or subjects|critically reviewed the article for important intellectual content	critically reviewed the article for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5808101	29430854	TFM	2	collected darunavir plasma levels	collected darunavir plasma levels	Performed the experiments	Investigation	YES
5606197	28966626	KC	2	participated in writing and correcting the paper	participated in writing and correcting the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5606197	28966626	LO	2	wrote the basic structure of the paper	wrote the basic structure of the paper	Wrote the paper	Writing - Original Draft	YES
4408092	25905920	LJR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408092	25905920	LJR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408092	25905920	LJR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408092	25905920	LJR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408092	25905920	RDB	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Conceptualized and initiated the project|Led the data collection	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408092	25905920	RDB	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Conceptualized and initiated the project|Led the data collection	Performed the experiments	Performed the experiments	Investigation	YES
4408092	25905920	RDB	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Conceptualized and initiated the project|Led the data collection	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408092	25905920	RDB	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Conceptualized and initiated the project|Led the data collection	Conceptualized and initiated the project	Conceived and designed the experiments	Conceptualization	YES
4408092	25905920	RDB	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Conceptualized and initiated the project|Led the data collection	Led the data collection	Performed the experiments	Investigation	YES
1762357	17183689	EK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762357	17183689	EK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762357	17183689	EK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762357	17183689	EK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762357	17183689	HN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762357	17183689	HN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762357	17183689	HN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762357	17183689	HN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762357	17183689	KA	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1762357	17183689	KA	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1762357	17183689	KA	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762357	17183689	KL	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762357	17183689	MR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762357	17183689	MR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762357	17183689	MR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762357	17183689	MR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762357	17183689	UK	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762357	17183689	UK	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5299494	27761943	A.L.	2	were reponsible for data acquisition and analysis	were reponsible for data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5299494	27761943	C.O.	2	were reponsible for data acquisition and analysis|were reponsible for drafting the manuscript and figures	were reponsible for data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5299494	27761943	C.O.	2	were reponsible for data acquisition and analysis|were reponsible for drafting the manuscript and figures	were reponsible for drafting the manuscript and figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5299494	27761943	C.S.J.	2	were reponsible for data acquisition and analysis|were reponsible for drafting the manuscript and figures	were reponsible for data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5299494	27761943	C.S.J.	2	were reponsible for data acquisition and analysis|were reponsible for drafting the manuscript and figures	were reponsible for drafting the manuscript and figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5299494	27761943	C.W.	2	were reponsible for data acquisition and analysis	were reponsible for data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5299494	27761943	D.C.	2	were reponsible for data acquisition and analysis	were reponsible for data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5299494	27761943	E.M.	2	were reponsible for study concept and design	were reponsible for study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5299494	27761943	G.C.L.	2	were reponsible for study concept and design|were reponsible for drafting the manuscript and figures	were reponsible for study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5299494	27761943	G.C.L.	2	were reponsible for study concept and design|were reponsible for drafting the manuscript and figures	were reponsible for drafting the manuscript and figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5299494	27761943	J.S.	2	were reponsible for study concept and design|were reponsible for drafting the manuscript and figures	were reponsible for study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5299494	27761943	J.S.	2	were reponsible for study concept and design|were reponsible for drafting the manuscript and figures	were reponsible for drafting the manuscript and figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5299494	27761943	L.C.	2	were reponsible for study concept and design|were reponsible for data acquisition and analysis|were reponsible for drafting the manuscript and figures	were reponsible for study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5299494	27761943	L.C.	2	were reponsible for study concept and design|were reponsible for data acquisition and analysis|were reponsible for drafting the manuscript and figures	were reponsible for data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5299494	27761943	L.C.	2	were reponsible for study concept and design|were reponsible for data acquisition and analysis|were reponsible for drafting the manuscript and figures	were reponsible for drafting the manuscript and figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5299494	27761943	N.T.	2	were reponsible for data acquisition and analysis	were reponsible for data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5299494	27761943	T.A.	2	were reponsible for data acquisition and analysis|were reponsible for drafting the manuscript and figures	were reponsible for data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5299494	27761943	T.A.	2	were reponsible for data acquisition and analysis|were reponsible for drafting the manuscript and figures	were reponsible for drafting the manuscript and figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5299494	27761943	T.E.	2	were reponsible for study concept and design|were reponsible for data acquisition and analysis|were reponsible for drafting the manuscript and figures	were reponsible for study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5299494	27761943	T.E.	2	were reponsible for study concept and design|were reponsible for data acquisition and analysis|were reponsible for drafting the manuscript and figures	were reponsible for data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5299494	27761943	T.E.	2	were reponsible for study concept and design|were reponsible for data acquisition and analysis|were reponsible for drafting the manuscript and figures	were reponsible for drafting the manuscript and figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5299494	27761943	V.D.	2	were reponsible for data acquisition and analysis|were reponsible for drafting the manuscript and figures	were reponsible for data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5299494	27761943	V.D.	2	were reponsible for data acquisition and analysis|were reponsible for drafting the manuscript and figures	were reponsible for drafting the manuscript and figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5405496	28446146	CDW	2	performed the bioinformatic analyses	performed the bioinformatic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5405496	28446146	EM	2	identified and annotated transposable elements	identified and annotated transposable elements	Performed the experiments	Investigation	YES
5405496	28446146	FG	2	performed all the experiments	performed all the experiments	Performed the experiments	Investigation	YES
5405496	28446146	LS	2	performed the bioinformatic analyses	performed the bioinformatic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5405496	28446146	NG	2	carried out the sorting experiments	carried out the sorting experiments	Performed the experiments	Investigation	YES
5405496	28446146	OA	2	performed the bioinformatic analyses	performed the bioinformatic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5405496	28446146	SD	2	conceived the study and wrote the paper	conceived the study and wrote the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5808102	29430845	BES	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5808102	29430845	HL	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5808102	29430845	HZQ	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5808102	29430845	JMS	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5808102	29430845	KRA	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5808102	29430845	S. All	2	authors revised and approved the manuscript before submission	authors revised and approved the manuscript before submission	Wrote the paper	Writing - Review & Editing	YES
5808102	29430845	SHV	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5808102	29430845	YL	2	performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
5808102	29430845	YR	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5808102	29430845	YS	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
3250981	22214263	BBB	2	selected the patient studies and performed the lesion delineation	selected the patient studies and performed the lesion delineation	Performed the experiments	Investigation	YES
3250981	22214263	BF	2	performed part of the data analysis and is the main author of the manuscript	performed part of the data analysis and is the main author of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3250981	22214263	JK	2	provided intellectual input and reviewed the manuscript	provided intellectual input and reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
3250981	22214263	JL	2	performed the phantom measurements and the image reconstruction	performed the phantom measurements and the image reconstruction	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
3250981	22214263	JS	2	provided intellectual input and reviewed the manuscript	provided intellectual input and reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
3250981	22214263	JVDH	2	implemented a prototype of the 3d bf for initial testing and wrote part of the manuscript	implemented a prototype of the 3d bf for initial testing and wrote part of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3250981	22214263	LO	2	performed part of the data analysis	performed part of the data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
1762358	17183634	AL	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762358	17183634	AL	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762358	17183634	AR	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762358	17183634	CB	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762358	17183634	HR	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762358	17183634	HW	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762358	17183634	HW	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762358	17183634	IL	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762358	17183634	IL	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762358	17183634	MJ	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762358	17183634	MJ	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762358	17183634	Mv Cd	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762358	17183634	Mv Cd	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762358	17183634	PA	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762358	17183634	SD	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762358	17183634	SD	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762358	17183634	TV	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5609103	28970845	AF	2	performed experiments with confocal microscopy	performed experiments with confocal microscopy	Performed the experiments	Investigation	YES
5609103	28970845	AV	2	designed and performed most of the experiments, conceived the project and wrote the paper	designed and performed most of the experiments, conceived the project and wrote the paper	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Writing - Original Draft	YES
5609103	28970845	EB	2	conceived the project and supervised writing	conceived the project and supervised writing	Conceived and designed the experiments|Wrote the paper	Conceptualization|Supervision	YES
5609103	28970845	HH	2	contributed to conception and design of the experiments and to editing of the text	contributed to conception and design of the experiments and to editing of the text	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5609103	28970845	KB	2	contributed to conception and design of the experiments and to editing of the text	contributed to conception and design of the experiments and to editing of the text	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5609103	28970845	NI	2	designed and performed most of the experiments, conceived the project and wrote the paper	designed and performed most of the experiments, conceived the project and wrote the paper	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Writing - Original Draft	YES
5609103	28970845	VS	2	designed and performed most of the experiments, conceived the project and wrote the paper	designed and performed most of the experiments, conceived the project and wrote the paper	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Writing - Original Draft	YES
3250982	22214307	PET	2	imaging studies	imaging studies	Analyzed the data	Visualization	YES
3250982	22214307	RMR	2	wrote the manuscript with the	wrote the manuscript with the	Wrote the paper	Writing - Original Draft	YES
3250982	22214307	all authors	2	assisted with the wrote the manuscript with the	assisted with the wrote the manuscript with the	Wrote the paper	Writing - Original Draft	YES
5810310	29178197	AKC	2	contributed to the concept and design of the study|contributed to the implementation of the intervention|drafted the first manuscript	contributed to the concept and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5810310	29178197	AKC	2	contributed to the concept and design of the study|contributed to the implementation of the intervention|drafted the first manuscript	contributed to the implementation of the intervention	Performed the experiments	Investigation	YES
5810310	29178197	AKC	2	contributed to the concept and design of the study|contributed to the implementation of the intervention|drafted the first manuscript	drafted the first manuscript	Wrote the paper	Writing - Original Draft	YES
5810310	29178197	AM	2	contributed to the implementation of the intervention|reviewed and suggested revisions	contributed to the implementation of the intervention	Performed the experiments	Investigation	YES
5810310	29178197	AM	2	contributed to the implementation of the intervention|reviewed and suggested revisions	reviewed and suggested revisions	Wrote the paper	Writing - Review & Editing	YES
5810310	29178197	All authors	2	reviewed and approved the final manuscript	reviewed and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5810310	29178197	CG	2	contributed to the implementation of the intervention|contributed to acquisition of data|reviewed and suggested revisions	contributed to the implementation of the intervention	Performed the experiments	Investigation	YES
5810310	29178197	CG	2	contributed to the implementation of the intervention|contributed to acquisition of data|reviewed and suggested revisions	contributed to acquisition of data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5810310	29178197	CG	2	contributed to the implementation of the intervention|contributed to acquisition of data|reviewed and suggested revisions	reviewed and suggested revisions	Wrote the paper	Writing - Review & Editing	YES
5810310	29178197	DG	2	contributed to the concept and design of the study|contributed to the implementation of the intervention|reviewed and suggested revisions	contributed to the concept and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5810310	29178197	DG	2	contributed to the concept and design of the study|contributed to the implementation of the intervention|reviewed and suggested revisions	contributed to the implementation of the intervention	Performed the experiments	Investigation	YES
5810310	29178197	DG	2	contributed to the concept and design of the study|contributed to the implementation of the intervention|reviewed and suggested revisions	reviewed and suggested revisions	Wrote the paper	Writing - Review & Editing	YES
5810310	29178197	ET	2	contributed to the implementation of the intervention|contributed to acquisition of data|reviewed and suggested revisions	contributed to the implementation of the intervention	Performed the experiments	Investigation	YES
5810310	29178197	ET	2	contributed to the implementation of the intervention|contributed to acquisition of data|reviewed and suggested revisions	contributed to acquisition of data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5810310	29178197	ET	2	contributed to the implementation of the intervention|contributed to acquisition of data|reviewed and suggested revisions	reviewed and suggested revisions	Wrote the paper	Writing - Review & Editing	YES
5810310	29178197	JN	2	contributed to the implementation of the intervention|contributed to acquisition of data|reviewed and suggested revisions	contributed to the implementation of the intervention	Performed the experiments	Investigation	YES
5810310	29178197	JN	2	contributed to the implementation of the intervention|contributed to acquisition of data|reviewed and suggested revisions	contributed to acquisition of data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5810310	29178197	JN	2	contributed to the implementation of the intervention|contributed to acquisition of data|reviewed and suggested revisions	reviewed and suggested revisions	Wrote the paper	Writing - Review & Editing	YES
5810310	29178197	MA	2	contributed to the concept and design of the study|reviewed and suggested revisions	contributed to the concept and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5810310	29178197	MA	2	contributed to the concept and design of the study|reviewed and suggested revisions	reviewed and suggested revisions	Wrote the paper	Writing - Review & Editing	YES
5810310	29178197	MvL	2	contributed to the concept and design of the study|contributed to data analysis and/or interpretation of the data|drafted the first manuscript	contributed to the concept and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5810310	29178197	MvL	2	contributed to the concept and design of the study|contributed to data analysis and/or interpretation of the data|drafted the first manuscript	contributed to data analysis and/or interpretation of the data	Analyzed the data	Formal analysis	YES
5810310	29178197	MvL	2	contributed to the concept and design of the study|contributed to data analysis and/or interpretation of the data|drafted the first manuscript	drafted the first manuscript	Wrote the paper	Writing - Original Draft	YES
5810310	29178197	RM	2	contributed to the concept and design of the study|contributed to data analysis and/or interpretation of the data|drafted the first manuscript	contributed to the concept and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5810310	29178197	RM	2	contributed to the concept and design of the study|contributed to data analysis and/or interpretation of the data|drafted the first manuscript	contributed to data analysis and/or interpretation of the data	Analyzed the data	Formal analysis	YES
5810310	29178197	RM	2	contributed to the concept and design of the study|contributed to data analysis and/or interpretation of the data|drafted the first manuscript	drafted the first manuscript	Wrote the paper	Writing - Original Draft	YES
5810310	29178197	SH	2	contributed to the implementation of the intervention|reviewed and suggested revisions	contributed to the implementation of the intervention	Performed the experiments	Investigation	YES
5810310	29178197	SH	2	contributed to the implementation of the intervention|reviewed and suggested revisions	reviewed and suggested revisions	Wrote the paper	Writing - Review & Editing	YES
5810310	29178197	SKS	2	contributed to acquisition of data|reviewed and suggested revisions	contributed to acquisition of data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5810310	29178197	SKS	2	contributed to acquisition of data|reviewed and suggested revisions	reviewed and suggested revisions	Wrote the paper	Writing - Review & Editing	YES
5810310	29178197	TB	2	contributed to the implementation of the intervention|contributed to acquisition of data|reviewed and suggested revisions	contributed to the implementation of the intervention	Performed the experiments	Investigation	YES
5810310	29178197	TB	2	contributed to the implementation of the intervention|contributed to acquisition of data|reviewed and suggested revisions	contributed to acquisition of data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5810310	29178197	TB	2	contributed to the implementation of the intervention|contributed to acquisition of data|reviewed and suggested revisions	reviewed and suggested revisions	Wrote the paper	Writing - Review & Editing	YES
5810310	29178197	VB	2	contributed to acquisition of data|reviewed and suggested revisions	contributed to acquisition of data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5810310	29178197	VB	2	contributed to acquisition of data|reviewed and suggested revisions	reviewed and suggested revisions	Wrote the paper	Writing - Review & Editing	YES
5810310	29178197	VS	2	contributed to the implementation of the intervention|contributed to acquisition of data|reviewed and suggested revisions	contributed to the implementation of the intervention	Performed the experiments	Investigation	YES
5810310	29178197	VS	2	contributed to the implementation of the intervention|contributed to acquisition of data|reviewed and suggested revisions	contributed to acquisition of data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5810310	29178197	VS	2	contributed to the implementation of the intervention|contributed to acquisition of data|reviewed and suggested revisions	reviewed and suggested revisions	Wrote the paper	Writing - Review & Editing	YES
5299616	27863444	A.J.S.	2	contributed to acquisition of data, analysis, and interpretation of the data|contributed to drafting the manuscript and figures	contributed to acquisition of data, analysis, and interpretation of the data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5299616	27863444	A.J.S.	2	contributed to acquisition of data, analysis, and interpretation of the data|contributed to drafting the manuscript and figures	contributed to drafting the manuscript and figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5299616	27863444	All authors	2	reviewed the manuscript and approved the final version of the manuscript	reviewed the manuscript and approved the final version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5299616	27863444	B.F.B.	2	contributed to acquisition of data, analysis, and interpretation of the data	contributed to acquisition of data, analysis, and interpretation of the data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5299616	27863444	C.R.J.	2	contributed to acquisition of data, analysis, and interpretation of the data	contributed to acquisition of data, analysis, and interpretation of the data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5299616	27863444	D.S.K.	2	contributed to acquisition of data, analysis, and interpretation of the data	contributed to acquisition of data, analysis, and interpretation of the data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5299616	27863444	D.T.J.	2	contributed to acquisition of data, analysis, and interpretation of the data	contributed to acquisition of data, analysis, and interpretation of the data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5299616	27863444	J.A.F.	2	contributed to acquisition of data, analysis, and interpretation of the data	contributed to acquisition of data, analysis, and interpretation of the data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5299616	27863444	J.G.R.	2	contributed to acquisition of data, analysis, and interpretation of the data	contributed to acquisition of data, analysis, and interpretation of the data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5299616	27863444	J.L.G.	2	contributed to acquisition of data, analysis, and interpretation of the data	contributed to acquisition of data, analysis, and interpretation of the data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5299616	27863444	K.K.	2	contributed to study concept and design|contributed to acquisition of data, analysis, and interpretation of the data|contributed to drafting the manuscript and figures	contributed to study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5299616	27863444	K.K.	2	contributed to study concept and design|contributed to acquisition of data, analysis, and interpretation of the data|contributed to drafting the manuscript and figures	contributed to acquisition of data, analysis, and interpretation of the data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5299616	27863444	K.K.	2	contributed to study concept and design|contributed to acquisition of data, analysis, and interpretation of the data|contributed to drafting the manuscript and figures	contributed to drafting the manuscript and figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5299616	27863444	M.E.M.	2	contributed to acquisition of data, analysis, and interpretation of the data	contributed to acquisition of data, analysis, and interpretation of the data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5299616	27863444	M.L.S.	2	contributed to acquisition of data, analysis, and interpretation of the data	contributed to acquisition of data, analysis, and interpretation of the data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5299616	27863444	N.T.	2	contributed to study concept and design|contributed to acquisition of data, analysis, and interpretation of the data|contributed to drafting the manuscript and figures	contributed to study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5299616	27863444	N.T.	2	contributed to study concept and design|contributed to acquisition of data, analysis, and interpretation of the data|contributed to drafting the manuscript and figures	contributed to acquisition of data, analysis, and interpretation of the data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5299616	27863444	N.T.	2	contributed to study concept and design|contributed to acquisition of data, analysis, and interpretation of the data|contributed to drafting the manuscript and figures	contributed to drafting the manuscript and figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5299616	27863444	R.C.P.	2	contributed to acquisition of data, analysis, and interpretation of the data	contributed to acquisition of data, analysis, and interpretation of the data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5299616	27863444	T.G.L.	2	contributed to study concept and design|contributed to acquisition of data, analysis, and interpretation of the data	contributed to study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5299616	27863444	T.G.L.	2	contributed to study concept and design|contributed to acquisition of data, analysis, and interpretation of the data	contributed to acquisition of data, analysis, and interpretation of the data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5299616	27863444	T.J.F.	2	contributed to acquisition of data, analysis, and interpretation of the data	contributed to acquisition of data, analysis, and interpretation of the data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5299616	27863444	V.J.L.	2	contributed to acquisition of data, analysis, and interpretation of the data	contributed to acquisition of data, analysis, and interpretation of the data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
3250983	22214534	DL	2	carried out immunohistochemistry on mda-mb-468 tumors	carried out immunohistochemistry on mda-mb-468 tumors	Performed the experiments	Investigation	YES
3250983	22214534	FD	2	corresponding author, designed and supervised the work	corresponding author, designed and supervised the work	Conceived and designed the experiments	Supervision	YES
3250983	22214534	FK-B	2	participated in the design of the study	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
3250983	22214534	JB	2	critically revised the manuscript and participated in drafting it	critically revised the manuscript and participated in drafting it	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3250983	22214534	JG	2	participated in the study design and was involved in drafting the manuscript	participated in the study design and was involved in drafting the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3250983	22214534	JW	2	produced the b-b4 antibody and critically revised the manuscript	produced the b-b4 antibody and critically revised the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
3250983	22214534	KB	2	carried out biodistribution studies	carried out biodistribution studies	Performed the experiments	Investigation	YES
3250983	22214534	MC	2	participated in the study design, critically revised the manuscript, and participated in drafting it	participated in the study design, critically revised the manuscript, and participated in drafting it	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft|Writing - Review & Editing	YES
3250983	22214534	RIT	2	radiolabeled antibody quality control	radiolabeled antibody quality control	Performed the experiments	Investigation|Validation	YES
3250983	22214534	SG	2	carried out cell culture and participated in the in vivo assays	carried out cell culture and participated in the in vivo assays	Performed the experiments	Investigation	YES
1762359	17183721	NT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762359	17183721	NT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762359	17183721	NT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762359	17183721	NT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762359	17183721	NT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762359	17183721	PC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762359	17183721	PC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762359	17183721	PC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762359	17183721	PC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762359	17183721	PC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5405530	28446153	CF	2	conceived the research|analyzed whole-genome sequencing data	conceived the research	Conceived and designed the experiments	Conceptualization	YES
5405530	28446153	CF	2	conceived the research|analyzed whole-genome sequencing data	analyzed whole-genome sequencing data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5405530	28446153	SS	2	conceived the research|performed the laboratory evolution|wrote the manuscript	conceived the research	Conceived and designed the experiments	Conceptualization	YES
5405530	28446153	SS	2	conceived the research|performed the laboratory evolution|wrote the manuscript	performed the laboratory evolution	Performed the experiments	Investigation	YES
5405530	28446153	SS	2	conceived the research|performed the laboratory evolution|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5405530	28446153	TH	2	performed the laboratory evolution	performed the laboratory evolution	Performed the experiments	Investigation	YES
4408093	25905493	MV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408093	25905493	MV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408093	25905493	MV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408093	25905493	MV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408093	25905493	PK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408093	25905493	PK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408093	25905493	PK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408093	25905493	PK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408093	25905493	TL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408093	25905493	TL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408093	25905493	TL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408093	25905493	TL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408093	25905493	TL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408093	25905493	TV	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408093	25905493	TV	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408093	25905493	TV	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5609105	28970842	IR	2	contributed equally to this work	contributed equally to this work	-	-	NO
5609105	28970842	MV-H	2	contributed equally to this work	contributed equally to this work	-	-	NO
5347854	27977873	A.N.	2	acquired the data and created the network	acquired the data and created the network	Performed the experiments	Investigation	YES
5347854	27977873	All authors	2	drafted the manuscript and the figures	drafted the manuscript and the figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5347854	27977873	I.T.	2	were involved in the conception and design of the study	were involved in the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5347854	27977873	J.R.	2	acquired the data and created the network	acquired the data and created the network	Performed the experiments	Investigation	YES
5347854	27977873	S.R.	2	were involved in the conception and design of the study	were involved in the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3250993	22214183	M-LP	2	assisted in the fdg studies	assisted in the fdg studies	-	-	NO
1762360	17183693	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762360	17183693	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762360	17183693	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762360	17183693	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762360	17183693	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408094	25906196	CD	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4408094	25906196	CD	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4408094	25906196	CT	PLoS5	Production of genomic sequences	Production of genomic sequences	Performed the experiments	Investigation	YES
4408094	25906196	EH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4408094	25906196	FB	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4408094	25906196	FD	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4408094	25906196	JL	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4408094	25906196	JP	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4408094	25906196	JP	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4408094	25906196	MR	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4408094	25906196	PM	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4408094	25906196	PP	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4408094	25906196	PP	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4408094	25906196	RAP	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4408094	25906196	RAP	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4408094	25906196	SH	PLoS5	Production of genomic sequences	Production of genomic sequences	Performed the experiments	Investigation	YES
5635522	29081945	All authors	2	contributed in writing the manuscript	contributed in writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5635522	29081945	C.M.S.	2	did the high-throughput screening with the covalent library	did the high-throughput screening with the covalent library	Performed the experiments	Investigation	YES
5635522	29081945	J-M.G.L.	2	performed the tumor sphere study with the gbm tumor initiating cell	performed the tumor sphere study with the gbm tumor initiating cell	Performed the experiments	Investigation	YES
5635522	29081945	S.M.	2	did all the synthesis, characterization, in vitro enzymatic assay and cell work|did the high-throughput screening with the covalent library	did all the synthesis, characterization, in vitro enzymatic assay and cell work	Performed the experiments	Investigation	YES
5635522	29081945	S.M.	2	did all the synthesis, characterization, in vitro enzymatic assay and cell work|did the high-throughput screening with the covalent library	did the high-throughput screening with the covalent library	Performed the experiments	Investigation	YES
5405539	28446145	LT	2	designed this research|carried out the experiments|analyzed data|revised the manuscript	designed this research	Conceived and designed the experiments	Methodology	YES
5405539	28446145	LT	2	designed this research|carried out the experiments|analyzed data|revised the manuscript	carried out the experiments	Performed the experiments	Investigation	YES
5405539	28446145	LT	2	designed this research|carried out the experiments|analyzed data|revised the manuscript	analyzed data	Analyzed the data	Formal analysis	YES
5405539	28446145	LT	2	designed this research|carried out the experiments|analyzed data|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5405539	28446145	QW	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5405539	28446145	RH	2	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5405539	28446145	SW	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5405539	28446145	TS	2	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5405539	28446145	WX	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5405539	28446145	XZ	2	designed this research|contributed the materials and reagents|revised the manuscript	designed this research	Conceived and designed the experiments	Methodology	YES
5405539	28446145	XZ	2	designed this research|contributed the materials and reagents|revised the manuscript	contributed the materials and reagents	Contributed reagents/materials/analysis tools	Resources	YES
5405539	28446145	XZ	2	designed this research|contributed the materials and reagents|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5405539	28446145	YZ	2	designed this research|contributed the materials and reagents|revised the manuscript	designed this research	Conceived and designed the experiments	Methodology	YES
5405539	28446145	YZ	2	designed this research|contributed the materials and reagents|revised the manuscript	contributed the materials and reagents	Contributed reagents/materials/analysis tools	Resources	YES
5405539	28446145	YZ	2	designed this research|contributed the materials and reagents|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
3250994	22214199	DD	2	has investigated and corrected the blood plasma curve for dispersion	has investigated and corrected the blood plasma curve for dispersion	Performed the experiments	Investigation	YES
3250994	22214199	FD	2	participated in the design of the study and helped to draft the manuscript	participated in the design of the study and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3250994	22214199	LM	2	designed and carried out the experimental studies and has written the manuscript	designed and carried out the experimental studies and has written the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
3250994	22214199	PB	2	participated in the design of the study and helped to draft the manuscript	participated in the design of the study and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5609112	28970844	AS	2	critically evaluated the manuscript	critically evaluated the manuscript	-	-	NO
5609112	28970844	BS	2	conceived the idea	conceived the idea	Conceived and designed the experiments	Conceptualization	YES
5609112	28970844	OG	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5609112	28970844	PS	2	critically evaluated the manuscript	critically evaluated the manuscript	-	-	NO
5609112	28970844	SK	2	conceived the idea|wrote the manuscript|critically evaluated the manuscript	conceived the idea	Conceived and designed the experiments	Conceptualization	YES
5609112	28970844	SK	2	conceived the idea|wrote the manuscript|critically evaluated the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5609112	28970844	SK	2	conceived the idea|wrote the manuscript|critically evaluated the manuscript	critically evaluated the manuscript	-	-	NO
5810312	29206357	CC	PLoS52	conceived and designed the original study|analysed the data|drafted the manuscript	conceived and designed the original study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5810312	29206357	CC	PLoS52	conceived and designed the original study|analysed the data|drafted the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
5810312	29206357	CC	PLoS52	conceived and designed the original study|analysed the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5810312	29206357	DH	PLoS52	conceived and designed the original study|critically reviewed the manuscript	conceived and designed the original study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5810312	29206357	DH	PLoS52	conceived and designed the original study|critically reviewed the manuscript	critically reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5810312	29206357	EC	PLoS52	conceived and designed the original study	conceived and designed the original study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5810312	29206357	EG	PLoS52	conceived and designed the original study|analysed the data|drafted the manuscript|critically reviewed the manuscript	conceived and designed the original study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5810312	29206357	EG	PLoS52	conceived and designed the original study|analysed the data|drafted the manuscript|critically reviewed the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
5810312	29206357	EG	PLoS52	conceived and designed the original study|analysed the data|drafted the manuscript|critically reviewed the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5810312	29206357	EG	PLoS52	conceived and designed the original study|analysed the data|drafted the manuscript|critically reviewed the manuscript	critically reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5810312	29206357	FCS	PLoS52	conceived and designed the original study|analysed the data	conceived and designed the original study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5810312	29206357	FCS	PLoS52	conceived and designed the original study|analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
5810312	29206357	FS	PLoS52	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5810312	29206357	GA	PLoS52	conceived and designed the original study|critically reviewed the manuscript	conceived and designed the original study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5810312	29206357	GA	PLoS52	conceived and designed the original study|critically reviewed the manuscript	critically reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5810312	29206357	JK	PLoS52	critically reviewed the manuscript	critically reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5810312	29206357	JN	PLoS52	conceived and designed the original study|critically reviewed the manuscript	conceived and designed the original study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5810312	29206357	JN	PLoS52	conceived and designed the original study|critically reviewed the manuscript	critically reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5810312	29206357	JW	PLoS52	analysed the data|drafted the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
5810312	29206357	JW	PLoS52	analysed the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5810312	29206357	LK	PLoS52	analysed the data|drafted the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
5810312	29206357	LK	PLoS52	analysed the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5810312	29206357	MRK	PLoS52	conceived and designed the original study|critically reviewed the manuscript	conceived and designed the original study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5810312	29206357	MRK	PLoS52	conceived and designed the original study|critically reviewed the manuscript	critically reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5810312	29206357	RK	PLoS52	analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
5810312	29206357	WC	PLoS52	critically reviewed the manuscript	critically reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5396275	28026041	The authors	2	contributed equally to the literature search and the writing and formatting of the review, and to critically reviewing the manuscript	contributed equally to the literature search and the writing and formatting of the review, and to critically reviewing the manuscript	Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
1762361	17183727	JE	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762361	17183727	JE	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762361	17183727	JE	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762361	17183727	JK	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762361	17183727	LD	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762361	17183727	LD	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762361	17183727	LD	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762361	17183727	NP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762361	17183727	NP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762361	17183727	NP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762361	17183727	RD	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762361	17183727	RD	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762361	17183727	RD	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762361	17183727	RG	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762361	17183727	RG	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4900130	27156058	JWS	1	Design of original survey and participant recruitment	Design of original survey and participant recruitment	Conceived and designed the experiments|Performed the experiments	Investigation	YES
4900130	27156058	SEH	1	Design of original survey and participant recruitment	Design of original survey and participant recruitment	Conceived and designed the experiments|Performed the experiments	Investigation	YES
4900130	27156058	SJH	1	Design of original survey and participant recruitment	Design of original survey and participant recruitment	Conceived and designed the experiments|Performed the experiments	Investigation	YES
4532803	26295044	Aline Silva	2	contributed equally to the study	contributed equally to the study	-	-	NO
4532803	26295044	Natalia Pessoa Rocha	2	contributed equally to the study	contributed equally to the study	-	-	NO
3250995	22214226	JM	2	performed the reference classifications	performed the reference classifications	Performed the experiments	Investigation	YES
3250995	22214226	LE	2	conceived of the study, and participated in its design and coordination and helped to draft the manuscript	conceived of the study, and participated in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
3250995	22214226	LJ	2	participated in the design of the study, performed the analysis of the toolboxes and drafted the manuscript	participated in the design of the study, performed the analysis of the toolboxes and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
3250995	22214226	ML	2	performed the reference classifications	performed the reference classifications	Performed the experiments	Investigation	YES
3250995	22214226	MO	2	performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
3250995	22214226	SES	2	performed the reference classifications	performed the reference classifications	Performed the experiments	Investigation	YES
4408095	25905921	AKT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Bioconductor	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408095	25905921	AKT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Bioconductor	Performed the experiments	Performed the experiments	Investigation	YES
4408095	25905921	AKT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Bioconductor	Analyzed the data	Analyzed the data	Formal analysis	YES
4408095	25905921	AKT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Bioconductor	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408095	25905921	AKT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Bioconductor	Bioconductor	Performed the experiments	Investigation	YES
4408095	25905921	DB	PLoS5	Analyzed the data|Wrote the paper|Provided biological interpretations of computational data|Organized and edited the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4408095	25905921	DB	PLoS5	Analyzed the data|Wrote the paper|Provided biological interpretations of computational data|Organized and edited the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408095	25905921	DB	PLoS5	Analyzed the data|Wrote the paper|Provided biological interpretations of computational data|Organized and edited the manuscript	Provided biological interpretations of computational data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
4408095	25905921	DB	PLoS5	Analyzed the data|Wrote the paper|Provided biological interpretations of computational data|Organized and edited the manuscript	Organized and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
4408095	25905921	FB	PLoS5	Analyzed the data|Wrote the paper|Provided biological interpretations of computational data	Analyzed the data	Analyzed the data	Formal analysis	YES
4408095	25905921	FB	PLoS5	Analyzed the data|Wrote the paper|Provided biological interpretations of computational data	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408095	25905921	FB	PLoS5	Analyzed the data|Wrote the paper|Provided biological interpretations of computational data	Provided biological interpretations of computational data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
4408095	25905921	JPK	PLoS5	Performed the experiments|Annotate interface to the iomics engine	Performed the experiments	Performed the experiments	Investigation	YES
4408095	25905921	JPK	PLoS5	Performed the experiments|Annotate interface to the iomics engine	Annotate interface to the iomics engine	-	-	NO
4408095	25905921	KS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Provided biological interpretations of computational data	Performed the experiments	Performed the experiments	Investigation	YES
4408095	25905921	KS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Provided biological interpretations of computational data	Analyzed the data	Analyzed the data	Formal analysis	YES
4408095	25905921	KS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Provided biological interpretations of computational data	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408095	25905921	KS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Provided biological interpretations of computational data	Provided biological interpretations of computational data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
4408095	25905921	PHA	PLoS5	Architect of iomics software suite that hosts the xomannotate software	Architect of iomics software suite that hosts the xomannotate software	Contributed reagents/materials/analysis tools	Software	YES
4408095	25905921	SG	PLoS5	Performed the experiments|Analyzed the data|Annotate interface to the iomics engine	Performed the experiments	Performed the experiments	Investigation	YES
4408095	25905921	SG	PLoS5	Performed the experiments|Analyzed the data|Annotate interface to the iomics engine	Analyzed the data	Analyzed the data	Formal analysis	YES
4408095	25905921	SG	PLoS5	Performed the experiments|Analyzed the data|Annotate interface to the iomics engine	Annotate interface to the iomics engine	-	-	NO
4408095	25905921	SR	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Tested and validated the xomannotate software	Performed the experiments	Performed the experiments	Investigation	YES
4408095	25905921	SR	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Tested and validated the xomannotate software	Analyzed the data	Analyzed the data	Formal analysis	YES
4408095	25905921	SR	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Tested and validated the xomannotate software	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408095	25905921	SR	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Tested and validated the xomannotate software	Tested and validated the xomannotate software	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software|Validation	YES
5609113	28970843	DD	PLoS52	conceived the original research plans|designed all of the experiments|performed all of the experiments|analyzed the data	conceived the original research plans	Conceived and designed the experiments	Conceptualization	YES
5609113	28970843	DD	PLoS52	conceived the original research plans|designed all of the experiments|performed all of the experiments|analyzed the data	designed all of the experiments	Conceived and designed the experiments	Methodology	YES
5609113	28970843	DD	PLoS52	conceived the original research plans|designed all of the experiments|performed all of the experiments|analyzed the data	performed all of the experiments	Performed the experiments	Investigation	YES
5609113	28970843	DD	PLoS52	conceived the original research plans|designed all of the experiments|performed all of the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5609113	28970843	LK	PLoS52	conceived the original research plans|designed all of the experiments|analyzed the data	conceived the original research plans	Conceived and designed the experiments	Conceptualization	YES
5609113	28970843	LK	PLoS52	conceived the original research plans|designed all of the experiments|analyzed the data	designed all of the experiments	Conceived and designed the experiments	Methodology	YES
5609113	28970843	LK	PLoS52	conceived the original research plans|designed all of the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5810314	29064168	A.V.H.	1	Conception of the work|Data collection|Data analysis and interpretation|Drafting the article|Final approval of the version to be published	Conception of the work	Conceived and designed the experiments	Conceptualization	YES
5810314	29064168	A.V.H.	1	Conception of the work|Data collection|Data analysis and interpretation|Drafting the article|Final approval of the version to be published	Data collection	Performed the experiments	Investigation	YES
5810314	29064168	A.V.H.	1	Conception of the work|Data collection|Data analysis and interpretation|Drafting the article|Final approval of the version to be published	Data analysis and interpretation	Analyzed the data	Formal analysis	YES
5810314	29064168	A.V.H.	1	Conception of the work|Data collection|Data analysis and interpretation|Drafting the article|Final approval of the version to be published	Drafting the article	Wrote the paper	Writing - Original Draft	YES
5810314	29064168	A.V.H.	1	Conception of the work|Data collection|Data analysis and interpretation|Drafting the article|Final approval of the version to be published	Final approval of the version to be published	-	-	NO
5810314	29064168	C.C.	1	Data analysis and interpretation|Critical revision of the article|Final approval of the version to be published	Data analysis and interpretation	Analyzed the data	Formal analysis	YES
5810314	29064168	C.C.	1	Data analysis and interpretation|Critical revision of the article|Final approval of the version to be published	Critical revision of the article	Wrote the paper	Writing - Review & Editing	YES
5810314	29064168	C.C.	1	Data analysis and interpretation|Critical revision of the article|Final approval of the version to be published	Final approval of the version to be published	-	-	NO
5810314	29064168	H.V.R.	1	Conception of the work|Data analysis and interpretation|Critical revision of the article|Final approval of the version to be published	Conception of the work	Conceived and designed the experiments	Conceptualization	YES
5810314	29064168	H.V.R.	1	Conception of the work|Data analysis and interpretation|Critical revision of the article|Final approval of the version to be published	Data analysis and interpretation	Analyzed the data	Formal analysis	YES
5810314	29064168	H.V.R.	1	Conception of the work|Data analysis and interpretation|Critical revision of the article|Final approval of the version to be published	Critical revision of the article	Wrote the paper	Writing - Review & Editing	YES
5810314	29064168	H.V.R.	1	Conception of the work|Data analysis and interpretation|Critical revision of the article|Final approval of the version to be published	Final approval of the version to be published	-	-	NO
5810314	29064168	L.M.	1	Data analysis and interpretation|Critical revision of the article|Final approval of the version to be published	Data analysis and interpretation	Analyzed the data	Formal analysis	YES
5810314	29064168	L.M.	1	Data analysis and interpretation|Critical revision of the article|Final approval of the version to be published	Critical revision of the article	Wrote the paper	Writing - Review & Editing	YES
5810314	29064168	L.M.	1	Data analysis and interpretation|Critical revision of the article|Final approval of the version to be published	Final approval of the version to be published	-	-	NO
5810314	29064168	R.B.	1	Conception of the work|Data analysis and interpretation|Critical revision of the article|Final approval of the version to be published	Conception of the work	Conceived and designed the experiments	Conceptualization	YES
5810314	29064168	R.B.	1	Conception of the work|Data analysis and interpretation|Critical revision of the article|Final approval of the version to be published	Data analysis and interpretation	Analyzed the data	Formal analysis	YES
5810314	29064168	R.B.	1	Conception of the work|Data analysis and interpretation|Critical revision of the article|Final approval of the version to be published	Critical revision of the article	Wrote the paper	Writing - Review & Editing	YES
5810314	29064168	R.B.	1	Conception of the work|Data analysis and interpretation|Critical revision of the article|Final approval of the version to be published	Final approval of the version to be published	-	-	NO
5810314	29064168	S.A.N.	1	Data analysis and interpretation|Critical revision of the article|Final approval of the version to be published	Data analysis and interpretation	Analyzed the data	Formal analysis	YES
5810314	29064168	S.A.N.	1	Data analysis and interpretation|Critical revision of the article|Final approval of the version to be published	Critical revision of the article	Wrote the paper	Writing - Review & Editing	YES
5810314	29064168	S.A.N.	1	Data analysis and interpretation|Critical revision of the article|Final approval of the version to be published	Final approval of the version to be published	-	-	NO
5405551	28441938	AW	PLoS52	supervised the project	supervised the project	-	Supervision	YES
5405551	28441938	All authors	PLoS52	reviewed and approved this manuscript	reviewed and approved this manuscript	Wrote the paper	Writing - Review & Editing	YES
5405551	28441938	FR	PLoS52	developed the analysis pipeline	developed the analysis pipeline	-	-	NO
5405551	28441938	GL	PLoS52	developed the analysis pipeline	developed the analysis pipeline	-	-	NO
5405551	28441938	JM	PLoS52	designed the project|performed the wet lab work|performed the data interpretation|wrote the paper|supervised the project	designed the project	Conceived and designed the experiments	Methodology	YES
5405551	28441938	JM	PLoS52	designed the project|performed the wet lab work|performed the data interpretation|wrote the paper|supervised the project	performed the wet lab work	Performed the experiments	Investigation	YES
5405551	28441938	JM	PLoS52	designed the project|performed the wet lab work|performed the data interpretation|wrote the paper|supervised the project	performed the data interpretation	Analyzed the data	Formal analysis	YES
5405551	28441938	JM	PLoS52	designed the project|performed the wet lab work|performed the data interpretation|wrote the paper|supervised the project	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5405551	28441938	JM	PLoS52	designed the project|performed the wet lab work|performed the data interpretation|wrote the paper|supervised the project	supervised the project	-	Supervision	YES
5405551	28441938	MK	PLoS52	developed the analysis pipeline	developed the analysis pipeline	-	-	NO
5405551	28441938	PD	PLoS52	designed the project|wrote the paper|supervised the project	designed the project	Conceived and designed the experiments	Methodology	YES
5405551	28441938	PD	PLoS52	designed the project|wrote the paper|supervised the project	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5405551	28441938	PD	PLoS52	designed the project|wrote the paper|supervised the project	supervised the project	-	Supervision	YES
5405551	28441938	UDM	PLoS52	performed the wet lab work	performed the wet lab work	Performed the experiments	Investigation	YES
5405551	28441938	YK	PLoS52	developed the analysis pipeline	developed the analysis pipeline	-	-	NO
5518287	28480639	A.C.L.	1	Study concept and design|Data acquisition and analysis|Drafting of manuscript and tables	Study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5518287	28480639	A.C.L.	1	Study concept and design|Data acquisition and analysis|Drafting of manuscript and tables	Data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5518287	28480639	A.C.L.	1	Study concept and design|Data acquisition and analysis|Drafting of manuscript and tables	Drafting of manuscript and tables	Wrote the paper	Writing - Original Draft	YES
5518287	28480639	A.D.	1	Data acquisition and analysis	Data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5518287	28480639	C.M.	1	Data acquisition and analysis	Data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5518287	28480639	D.J.L.	1	Study concept and design|Data acquisition and analysis|Drafting of manuscript and tables	Study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5518287	28480639	D.J.L.	1	Study concept and design|Data acquisition and analysis|Drafting of manuscript and tables	Data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5518287	28480639	D.J.L.	1	Study concept and design|Data acquisition and analysis|Drafting of manuscript and tables	Drafting of manuscript and tables	Wrote the paper	Writing - Original Draft	YES
5518287	28480639	J.H.W.	1	Data acquisition and analysis	Data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5518287	28480639	K.G.F.	1	Data acquisition and analysis|Drafting of manuscript and tables	Data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5518287	28480639	K.G.F.	1	Data acquisition and analysis|Drafting of manuscript and tables	Drafting of manuscript and tables	Wrote the paper	Writing - Original Draft	YES
5518287	28480639	L.M.	1	Data acquisition and analysis	Data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5518287	28480639	M.S.	1	Study concept and design	Study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5518287	28480639	P.M.A.	1	Study concept and design|Drafting of manuscript and tables	Study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5518287	28480639	P.M.A.	1	Study concept and design|Drafting of manuscript and tables	Drafting of manuscript and tables	Wrote the paper	Writing - Original Draft	YES
5518287	28480639	R.R.	1	Data acquisition and analysis	Data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5518287	28480639	S.A.-D.	1	Study concept and design|Data acquisition and analysis	Study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5518287	28480639	S.A.-D.	1	Study concept and design|Data acquisition and analysis	Data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5518287	28480639	S.H.A.	1	Study concept and design	Study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5518287	28480639	S.M.	1	Study concept and design|Data acquisition and analysis|Drafting of manuscript and tables	Study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5518287	28480639	S.M.	1	Study concept and design|Data acquisition and analysis|Drafting of manuscript and tables	Data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5518287	28480639	S.M.	1	Study concept and design|Data acquisition and analysis|Drafting of manuscript and tables	Drafting of manuscript and tables	Wrote the paper	Writing - Original Draft	YES
5518287	28480639	S.M.L.	1	Study concept and design|Data acquisition and analysis|Drafting of manuscript and tables	Study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5518287	28480639	S.M.L.	1	Study concept and design|Data acquisition and analysis|Drafting of manuscript and tables	Data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5518287	28480639	S.M.L.	1	Study concept and design|Data acquisition and analysis|Drafting of manuscript and tables	Drafting of manuscript and tables	Wrote the paper	Writing - Original Draft	YES
5518287	28480639	U.W.	1	Data acquisition and analysis	Data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5518287	28480639	V.S.	1	Study concept and design|Data acquisition and analysis|Drafting of manuscript and tables	Study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5518287	28480639	V.S.	1	Study concept and design|Data acquisition and analysis|Drafting of manuscript and tables	Data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5518287	28480639	V.S.	1	Study concept and design|Data acquisition and analysis|Drafting of manuscript and tables	Drafting of manuscript and tables	Wrote the paper	Writing - Original Draft	YES
3250998	22214225	GAMSvD	2	designed and coordinated the study and reviewed all the data and the manuscript	designed and coordinated the study and reviewed all the data and the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Review & Editing	YES
3250998	22214225	GWMV	2	reviewed the experimental data and manuscript	reviewed the experimental data and manuscript	Wrote the paper	Writing - Review & Editing	YES
3250998	22214225	IHCdR	2	performed the labeling and conjugation experiments and the qc analyses	performed the labeling and conjugation experiments and the qc analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3250998	22214225	MAS	2	performed the labeling and conjugation experiments and the qc analyses	performed the labeling and conjugation experiments and the qc analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3250998	22214225	MSvW	2	performed all animal studies	performed all animal studies	Performed the experiments	Investigation	YES
3250998	22214225	RC	2	coordinated and executed all the experiments and drafted the manuscript	coordinated and executed all the experiments and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Project administration|Writing - Original Draft	YES
1762362	17183638	CF	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762362	17183638	CF	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762362	17183638	DK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762362	17183638	DK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762362	17183638	DK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762362	17183638	DK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762362	17183638	HH	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762362	17183638	HH	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4532804	26295046	Gang Lin	2	contributed equally to this work	contributed equally to this work	-	-	NO
4532804	26295046	Jingying Fu	2	contributed equally to this work	contributed equally to this work	-	-	NO
4917887	27240151	BRHS	2	participants, collected data, and approved the final version	participants, collected data, and approved the final version	Performed the experiments	Investigation	YES
4917887	27240151	CS	2	processed the brhs data, performed statistical analyses, drafted and revised the manuscript, and incorporated revisions of co-authors, and approved the final version	processed the brhs data, performed statistical analyses, drafted and revised the manuscript, and incorporated revisions of co-authors, and approved the final version	Analyzed the data|Wrote the paper	Data curation|Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
4917887	27240151	GSW	2	contributed to the design of the study, to the acquisition of data, revised the manuscript, and approved the final version	contributed to the design of the study, to the acquisition of data, revised the manuscript, and approved the final version	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Methodology|Resources|Writing - Review & Editing	YES
4917887	27240151	IF	2	contributed to the design of the study, to the acquisition of data, revised the manuscript, and approved the final version	contributed to the design of the study, to the acquisition of data, revised the manuscript, and approved the final version	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Methodology|Resources|Writing - Review & Editing	YES
4917887	27240151	PHW	2	contributed to the design of the study, to the acquisition of data, revised the manuscript, and approved the final version	contributed to the design of the study, to the acquisition of data, revised the manuscript, and approved the final version	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Methodology|Resources|Writing - Review & Editing	YES
4917887	27240151	RWM	2	raised grant funding, contributed to the design of the study, to the acquisition of data, to the supervision of statistical analyses, drafted and revised the manuscript, and approved the final version	raised grant funding, contributed to the design of the study, to the acquisition of data, to the supervision of statistical analyses, drafted and revised the manuscript, and approved the final version	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Funding acquisition|Investigation|Methodology|Resources|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
4917887	27240151	SB	2	processed the prosper data, performed statistical analyses, revised the manuscript, and approved the final version	processed the prosper data, performed statistical analyses, revised the manuscript, and approved the final version	Analyzed the data|Wrote the paper	Data curation|Formal analysis|Writing - Review & Editing	YES
5609544	28970841	QZ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5609544	28970841	R-KX	PLoS52	designed the experiments|revised the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5609544	28970841	R-KX	PLoS52	designed the experiments|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5609544	28970841	Z-DL	PLoS52	designed the experiments|performed the experiments|drafted the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5609544	28970841	Z-DL	PLoS52	designed the experiments|performed the experiments|drafted the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5609544	28970841	Z-DL	PLoS52	designed the experiments|performed the experiments|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5609544	28970841	Z-NH	PLoS52	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5406980	28449654	AH	2	executed the lab work	executed the lab work	Performed the experiments	Investigation	YES
5406980	28449654	BW	2	conceived the project, analysed and interpreted the results|designed the experimental set up|wrote the initial draft and all authors critically revised the manuscript	conceived the project, analysed and interpreted the results	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
5406980	28449654	BW	2	conceived the project, analysed and interpreted the results|designed the experimental set up|wrote the initial draft and all authors critically revised the manuscript	designed the experimental set up	Conceived and designed the experiments|Performed the experiments	Methodology	YES
5406980	28449654	BW	2	conceived the project, analysed and interpreted the results|designed the experimental set up|wrote the initial draft and all authors critically revised the manuscript	wrote the initial draft and all authors critically revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5406980	28449654	HB	2	designed the experimental set up	designed the experimental set up	Conceived and designed the experiments|Performed the experiments	Methodology	YES
5406980	28449654	KJ	2	conceived the project, analysed and interpreted the results|designed the experimental set up|executed the lab work	conceived the project, analysed and interpreted the results	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
5406980	28449654	KJ	2	conceived the project, analysed and interpreted the results|designed the experimental set up|executed the lab work	designed the experimental set up	Conceived and designed the experiments|Performed the experiments	Methodology	YES
5406980	28449654	KJ	2	conceived the project, analysed and interpreted the results|designed the experimental set up|executed the lab work	executed the lab work	Performed the experiments	Investigation	YES
5406980	28449654	KK	2	designed the experimental set up	designed the experimental set up	Conceived and designed the experiments|Performed the experiments	Methodology	YES
5406980	28449654	LS	2	conceived the project, analysed and interpreted the results|designed the experimental set up|executed the lab work|wrote the initial draft and all authors critically revised the manuscript	conceived the project, analysed and interpreted the results	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
5406980	28449654	LS	2	conceived the project, analysed and interpreted the results|designed the experimental set up|executed the lab work|wrote the initial draft and all authors critically revised the manuscript	designed the experimental set up	Conceived and designed the experiments|Performed the experiments	Methodology	YES
5406980	28449654	LS	2	conceived the project, analysed and interpreted the results|designed the experimental set up|executed the lab work|wrote the initial draft and all authors critically revised the manuscript	executed the lab work	Performed the experiments	Investigation	YES
5406980	28449654	LS	2	conceived the project, analysed and interpreted the results|designed the experimental set up|executed the lab work|wrote the initial draft and all authors critically revised the manuscript	wrote the initial draft and all authors critically revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4408096	25905863	DS	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4408096	25905863	EE	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4408096	25905863	EH	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4408096	25905863	FL	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4408096	25905863	FL	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4408096	25905863	HM	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408096	25905863	KI	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4408096	25905863	MS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4408096	25905863	NG	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408096	25905863	NG	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408096	25905863	NG	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408096	25905863	NS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4408096	25905863	SM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4408096	25905863	WF	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5810315	29049854	PC	2	wrote the first draft of the letter and revised it until the final version	wrote the first draft of the letter and revised it until the final version	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5810315	29049854	PR	2	contributed to the revision of the letter until its current version	contributed to the revision of the letter until its current version	Wrote the paper	Writing - Review & Editing	YES
5519923	28470693	C.W.I.	2	developed the concept of this study|designed this study|acquired and analyzed data|drafted the manuscript and figures|contributed equally to this work	developed the concept of this study	Conceived and designed the experiments	Conceptualization	YES
5519923	28470693	C.W.I.	2	developed the concept of this study|designed this study|acquired and analyzed data|drafted the manuscript and figures|contributed equally to this work	designed this study	Conceived and designed the experiments	Methodology	YES
5519923	28470693	C.W.I.	2	developed the concept of this study|designed this study|acquired and analyzed data|drafted the manuscript and figures|contributed equally to this work	acquired and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5519923	28470693	C.W.I.	2	developed the concept of this study|designed this study|acquired and analyzed data|drafted the manuscript and figures|contributed equally to this work	drafted the manuscript and figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5519923	28470693	C.W.I.	2	developed the concept of this study|designed this study|acquired and analyzed data|drafted the manuscript and figures|contributed equally to this work	contributed equally to this work	-	-	NO
5519923	28470693	F.F.	2	acquired and analyzed data	acquired and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5519923	28470693	J.B.K.	2	developed the concept of this study|designed this study|acquired and analyzed data|contributed equally to this work	developed the concept of this study	Conceived and designed the experiments	Conceptualization	YES
5519923	28470693	J.B.K.	2	developed the concept of this study|designed this study|acquired and analyzed data|contributed equally to this work	designed this study	Conceived and designed the experiments	Methodology	YES
5519923	28470693	J.B.K.	2	developed the concept of this study|designed this study|acquired and analyzed data|contributed equally to this work	acquired and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5519923	28470693	J.B.K.	2	developed the concept of this study|designed this study|acquired and analyzed data|contributed equally to this work	contributed equally to this work	-	-	NO
5519923	28470693	J.M.B.	2	developed the concept of this study	developed the concept of this study	Conceived and designed the experiments	Conceptualization	YES
5519923	28470693	J.V.	2	developed the concept of this study	developed the concept of this study	Conceived and designed the experiments	Conceptualization	YES
5519923	28470693	M.R.	2	acquired and analyzed data|contributed equally to this work	acquired and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5519923	28470693	M.R.	2	acquired and analyzed data|contributed equally to this work	contributed equally to this work	-	-	NO
5519923	28470693	T.M.	2	acquired and analyzed data|drafted the manuscript and figures|contributed equally to this work	acquired and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5519923	28470693	T.M.	2	acquired and analyzed data|drafted the manuscript and figures|contributed equally to this work	drafted the manuscript and figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5519923	28470693	T.M.	2	acquired and analyzed data|drafted the manuscript and figures|contributed equally to this work	contributed equally to this work	-	-	NO
3251005	22214590	RM	2	conceived the idea, wrote the manuscript, and drew the graphics	conceived the idea, wrote the manuscript, and drew the graphics	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4532805	26295042	Alexis Roche	2	carried out collection, analysis, and interpretation of data|carried out writing of the report and taking decision to submit the paper for publication	carried out collection, analysis, and interpretation of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4532805	26295042	Alexis Roche	2	carried out collection, analysis, and interpretation of data|carried out writing of the report and taking decision to submit the paper for publication	carried out writing of the report and taking decision to submit the paper for publication	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4532805	26295042	Cristina Granziera	2	carried out study design|carried out collection, analysis, and interpretation of data|carried out writing of the report and taking decision to submit the paper for publication	carried out study design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4532805	26295042	Cristina Granziera	2	carried out study design|carried out collection, analysis, and interpretation of data|carried out writing of the report and taking decision to submit the paper for publication	carried out collection, analysis, and interpretation of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4532805	26295042	Cristina Granziera	2	carried out study design|carried out collection, analysis, and interpretation of data|carried out writing of the report and taking decision to submit the paper for publication	carried out writing of the report and taking decision to submit the paper for publication	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4532805	26295042	David Romascano	2	carried out collection, analysis, and interpretation of data|carried out writing of the report and taking decision to submit the paper for publication	carried out collection, analysis, and interpretation of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4532805	26295042	David Romascano	2	carried out collection, analysis, and interpretation of data|carried out writing of the report and taking decision to submit the paper for publication	carried out writing of the report and taking decision to submit the paper for publication	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4532805	26295042	David Rotzinger	2	carried out collection, analysis, and interpretation of data|carried out writing of the report and taking decision to submit the paper for publication	carried out collection, analysis, and interpretation of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4532805	26295042	David Rotzinger	2	carried out collection, analysis, and interpretation of data|carried out writing of the report and taking decision to submit the paper for publication	carried out writing of the report and taking decision to submit the paper for publication	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4532805	26295042	Djalel Meskaldji	2	carried out collection, analysis, and interpretation of data|carried out writing of the report and taking decision to submit the paper for publication	carried out collection, analysis, and interpretation of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4532805	26295042	Djalel Meskaldji	2	carried out collection, analysis, and interpretation of data|carried out writing of the report and taking decision to submit the paper for publication	carried out writing of the report and taking decision to submit the paper for publication	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4532805	26295042	Gloria Menegaz	2	carried out collection, analysis, and interpretation of data|carried out writing of the report and taking decision to submit the paper for publication	carried out collection, analysis, and interpretation of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4532805	26295042	Gloria Menegaz	2	carried out collection, analysis, and interpretation of data|carried out writing of the report and taking decision to submit the paper for publication	carried out writing of the report and taking decision to submit the paper for publication	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4532805	26295042	Guillaume Bonnier	2	carried out collection, analysis, and interpretation of data|carried out writing of the report and taking decision to submit the paper for publication	carried out collection, analysis, and interpretation of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4532805	26295042	Guillaume Bonnier	2	carried out collection, analysis, and interpretation of data|carried out writing of the report and taking decision to submit the paper for publication	carried out writing of the report and taking decision to submit the paper for publication	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4532805	26295042	Gunnar Krueger	2	carried out study design|carried out collection, analysis, and interpretation of data|carried out writing of the report and taking decision to submit the paper for publication	carried out study design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4532805	26295042	Gunnar Krueger	2	carried out study design|carried out collection, analysis, and interpretation of data|carried out writing of the report and taking decision to submit the paper for publication	carried out collection, analysis, and interpretation of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4532805	26295042	Gunnar Krueger	2	carried out study design|carried out collection, analysis, and interpretation of data|carried out writing of the report and taking decision to submit the paper for publication	carried out writing of the report and taking decision to submit the paper for publication	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4532805	26295042	Jean-Philippe Thiran	2	carried out writing of the report and taking decision to submit the paper for publication	carried out writing of the report and taking decision to submit the paper for publication	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4532805	26295042	Jens Frahm	2	carried out writing of the report and taking decision to submit the paper for publication	carried out writing of the report and taking decision to submit the paper for publication	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4532805	26295042	Myriam Schluep	2	carried out writing of the report and taking decision to submit the paper for publication	carried out writing of the report and taking decision to submit the paper for publication	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4532805	26295042	Renaud Du Pasquier	2	carried out writing of the report and taking decision to submit the paper for publication	carried out writing of the report and taking decision to submit the paper for publication	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4532805	26295042	Samanta Simioni	2	carried out collection, analysis, and interpretation of data|carried out writing of the report and taking decision to submit the paper for publication	carried out collection, analysis, and interpretation of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4532805	26295042	Samanta Simioni	2	carried out collection, analysis, and interpretation of data|carried out writing of the report and taking decision to submit the paper for publication	carried out writing of the report and taking decision to submit the paper for publication	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4532805	26295042	Tilman Johannes Sumpf	2	carried out writing of the report and taking decision to submit the paper for publication	carried out writing of the report and taking decision to submit the paper for publication	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4532805	26295042	Ying-Chia Lin	2	carried out collection, analysis, and interpretation of data|carried out writing of the report and taking decision to submit the paper for publication	carried out collection, analysis, and interpretation of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4532805	26295042	Ying-Chia Lin	2	carried out collection, analysis, and interpretation of data|carried out writing of the report and taking decision to submit the paper for publication	carried out writing of the report and taking decision to submit the paper for publication	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5609550	28970839	CL	2	participated in the implementation of the experiment, sample collection, and laboratory analysis	participated in the implementation of the experiment, sample collection, and laboratory analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5609550	28970839	GL	2	provided research ideas and designed the experiments|were also responsible for the revision of the paper	provided research ideas and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5609550	28970839	GL	2	provided research ideas and designed the experiments|were also responsible for the revision of the paper	were also responsible for the revision of the paper	Wrote the paper	Writing - Review & Editing	YES
5609550	28970839	GW	2	provided research ideas and designed the experiments|were also responsible for the revision of the paper	provided research ideas and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5609550	28970839	GW	2	provided research ideas and designed the experiments|were also responsible for the revision of the paper	were also responsible for the revision of the paper	Wrote the paper	Writing - Review & Editing	YES
5609550	28970839	HL	2	participated in the implementation of the experiment, sample collection, and laboratory analysis	participated in the implementation of the experiment, sample collection, and laboratory analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5609550	28970839	JZ	2	participated in the implementation of the experiment, sample collection, and laboratory analysis	participated in the implementation of the experiment, sample collection, and laboratory analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5609550	28970839	SX	2	provided research ideas and designed the experiments|were also responsible for the revision of the paper	provided research ideas and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5609550	28970839	SX	2	provided research ideas and designed the experiments|were also responsible for the revision of the paper	were also responsible for the revision of the paper	Wrote the paper	Writing - Review & Editing	YES
5609550	28970839	ZA	2	wrote the paper and participated in the implementation of the experiment, sample collection, laboratory analysis, and data analysis	wrote the paper and participated in the implementation of the experiment, sample collection, laboratory analysis, and data analysis	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
1762363	17183674	DW	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762363	17183674	DW	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762363	17183674	JR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762363	17183674	JR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762363	17183674	JR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762363	17183674	JR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3251007	22214348	JD	2	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3251007	22214348	MK	2	conceived and designed the study|carried out the experiments, analysis and drafted the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3251007	22214348	MK	2	conceived and designed the study|carried out the experiments, analysis and drafted the manuscript	carried out the experiments, analysis and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5408420	28449639	AM	PLoS5	Conceived and designed the project	Conceived and designed the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5408420	28449639	CA	PLoS5	Developed the software	Developed the software	Contributed reagents/materials/analysis tools	Software	YES
5408420	28449639	CF	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5408420	28449639	DR	PLoS5	Developed the software	Developed the software	Contributed reagents/materials/analysis tools	Software	YES
5408420	28449639	HT	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5408420	28449639	JC	PLoS5	Developed the software	Developed the software	Contributed reagents/materials/analysis tools	Software	YES
5408420	28449639	KG	PLoS5	Developed the software	Developed the software	Contributed reagents/materials/analysis tools	Software	YES
5408420	28449639	MV	PLoS5	Developed the software	Developed the software	Contributed reagents/materials/analysis tools	Software	YES
5408420	28449639	OW	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5408420	28449639	RSA	PLoS5	Developed the software|Analyzed the data	Developed the software	Contributed reagents/materials/analysis tools	Software	YES
5408420	28449639	RSA	PLoS5	Developed the software|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5408420	28449639	SA	PLoS5	Developed the software|Analyzed the data|Wrote the paper	Developed the software	Contributed reagents/materials/analysis tools	Software	YES
5408420	28449639	SA	PLoS5	Developed the software|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5408420	28449639	SA	PLoS5	Developed the software|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5408420	28449639	SVA	PLoS5	Conceived and designed the project|Developed the software	Conceived and designed the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5408420	28449639	SVA	PLoS5	Conceived and designed the project|Developed the software	Developed the software	Contributed reagents/materials/analysis tools	Software	YES
5408420	28449639	WFF	PLoS5	Conceived and designed the project|Analyzed the data|Wrote the paper	Conceived and designed the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5408420	28449639	WFF	PLoS5	Conceived and designed the project|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5408420	28449639	WFF	PLoS5	Conceived and designed the project|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5810316	29282882	BSG	2	edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5810316	29282882	CKC	2	edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5810316	29282882	GS	2	wrote the first draft|edited the manuscript	wrote the first draft	Wrote the paper	Writing - Original Draft	YES
5810316	29282882	GS	2	wrote the first draft|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5810316	29282882	IJ	2	wrote the first draft|edited the manuscript	wrote the first draft	Wrote the paper	Writing - Original Draft	YES
5810316	29282882	IJ	2	wrote the first draft|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5810316	29282882	LMM	2	edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5810316	29282882	PMM	2	edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5810316	29282882	SRP	2	edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5810316	29282882	YV	2	wrote the first draft|edited the manuscript	wrote the first draft	Wrote the paper	Writing - Original Draft	YES
5810316	29282882	YV	2	wrote the first draft|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
4408097	25905723	ALB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408097	25905723	ALB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4408097	25905723	ALB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4408097	25905723	GSD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408097	25905723	GSD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408097	25905723	GSD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408097	25905723	GSD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408097	25905723	GSD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408097	25905723	KAK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408097	25905723	KAK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408097	25905723	KAK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408097	25905723	KAK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408097	25905723	KAK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408097	25905723	PJA	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408097	25905723	PJA	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5519945	28512753	Jens Kuhle	1	Group	Group	-	-	NO
5519945	28512753	MD	1	Group	Group	-	-	NO
5519945	28512753	PhD	1	Group	Group	-	-	NO
4532807	26295040	Carla Cirillo	2	equally contributed to the paper	equally contributed to the paper	-	-	NO
4532807	26295040	Elena Capoccia	2	equally contributed to the paper	equally contributed to the paper	-	-	NO
5609569	28970840	DT	2	compiled the major parts of the text	compiled the major parts of the text	-	-	NO
5609569	28970840	JP	2	contributed with text on eggplant wild relatives	contributed with text on eggplant wild relatives	Wrote the paper	Writing - Original Draft	YES
5609569	28970840	MR	2	contributed with inputs on eggplant taxonomy and breeding	contributed with inputs on eggplant taxonomy and breeding	Performed the experiments	Investigation	YES
5609569	28970840	SS	2	contributed with text on genetic resources	contributed with text on genetic resources	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Resources|Writing - Original Draft	YES
5609569	28970840	TW	2	contributed with inputs on eggplant taxonomy and breeding	contributed with inputs on eggplant taxonomy and breeding	Performed the experiments	Investigation	YES
5609569	28970840	YC	2	contributed with reviewing databases	contributed with reviewing databases	Contributed reagents/materials/analysis tools	Resources|Software	YES
1762364	17183710	AM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762364	17183710	AM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762364	17183710	AM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762364	17183710	EB	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762364	17183710	MM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762364	17183710	MM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762364	17183710	MM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762364	17183710	SS	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762364	17183710	TZ	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762364	17183710	TZ	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
3251037	22214497	All authors	2	were involved in the design of the trial and took part in the interpretation of the data and in revising the manuscript|read and approved the final manuscript|have given their final approval of the version to be published	were involved in the design of the trial and took part in the interpretation of the data and in revising the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
3251037	22214497	All authors	2	were involved in the design of the trial and took part in the interpretation of the data and in revising the manuscript|read and approved the final manuscript|have given their final approval of the version to be published	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
3251037	22214497	All authors	2	were involved in the design of the trial and took part in the interpretation of the data and in revising the manuscript|read and approved the final manuscript|have given their final approval of the version to be published	have given their final approval of the version to be published	-	-	NO
3251037	22214497	ES	2	carried out the analysis of data and drafted the manuscript|carried out the extraction of total rna	carried out the analysis of data and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3251037	22214497	ES	2	carried out the analysis of data and drafted the manuscript|carried out the extraction of total rna	carried out the extraction of total rna	Performed the experiments	Investigation	YES
3251037	22214497	NR	2	carried out the animal trial	carried out the animal trial	Performed the experiments	Investigation	YES
3251037	22214497	TP	2	carried out the extraction of total rna	carried out the extraction of total rna	Performed the experiments	Investigation	YES
5047033	27529390	AB	PLoS52	analysed the data|interpreted the data|gave critical intellectual input, and contributed in drafting revised versions of the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
5047033	27529390	AB	PLoS52	analysed the data|interpreted the data|gave critical intellectual input, and contributed in drafting revised versions of the manuscript	interpreted the data	Analyzed the data	Formal analysis	YES
5047033	27529390	AB	PLoS52	analysed the data|interpreted the data|gave critical intellectual input, and contributed in drafting revised versions of the manuscript	gave critical intellectual input, and contributed in drafting revised versions of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5047033	27529390	AK	PLoS52	interpreted the data|gave critical intellectual input, and contributed in drafting revised versions of the manuscript	interpreted the data	Analyzed the data	Formal analysis	YES
5047033	27529390	AK	PLoS52	interpreted the data|gave critical intellectual input, and contributed in drafting revised versions of the manuscript	gave critical intellectual input, and contributed in drafting revised versions of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5047033	27529390	All authors	PLoS52	gave their final approval of the version to be published	gave their final approval of the version to be published	-	-	NO
5047033	27529390	BJC	PLoS52	interpreted the data|gave critical intellectual input, and contributed in drafting revised versions of the manuscript	interpreted the data	Analyzed the data	Formal analysis	YES
5047033	27529390	BJC	PLoS52	interpreted the data|gave critical intellectual input, and contributed in drafting revised versions of the manuscript	gave critical intellectual input, and contributed in drafting revised versions of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5047033	27529390	DC	PLoS52	analysed the data|interpreted the data|drafted the first version of the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
5047033	27529390	DC	PLoS52	analysed the data|interpreted the data|drafted the first version of the manuscript	interpreted the data	Analyzed the data	Formal analysis	YES
5047033	27529390	DC	PLoS52	analysed the data|interpreted the data|drafted the first version of the manuscript	drafted the first version of the manuscript	Wrote the paper	Writing - Original Draft	YES
5047033	27529390	FLW	PLoS52	interpreted the data|gave critical intellectual input, and contributed in drafting revised versions of the manuscript	interpreted the data	Analyzed the data	Formal analysis	YES
5047033	27529390	FLW	PLoS52	interpreted the data|gave critical intellectual input, and contributed in drafting revised versions of the manuscript	gave critical intellectual input, and contributed in drafting revised versions of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5047033	27529390	GR	PLoS52	interpreted the data|gave critical intellectual input, and contributed in drafting revised versions of the manuscript	interpreted the data	Analyzed the data	Formal analysis	YES
5047033	27529390	GR	PLoS52	interpreted the data|gave critical intellectual input, and contributed in drafting revised versions of the manuscript	gave critical intellectual input, and contributed in drafting revised versions of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5047033	27529390	JG	PLoS52	interpreted the data|gave critical intellectual input, and contributed in drafting revised versions of the manuscript	interpreted the data	Analyzed the data	Formal analysis	YES
5047033	27529390	JG	PLoS52	interpreted the data|gave critical intellectual input, and contributed in drafting revised versions of the manuscript	gave critical intellectual input, and contributed in drafting revised versions of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5047033	27529390	VB	PLoS52	analysed the data|interpreted the data|gave critical intellectual input, and contributed in drafting revised versions of the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
5047033	27529390	VB	PLoS52	analysed the data|interpreted the data|gave critical intellectual input, and contributed in drafting revised versions of the manuscript	interpreted the data	Analyzed the data	Formal analysis	YES
5047033	27529390	VB	PLoS52	analysed the data|interpreted the data|gave critical intellectual input, and contributed in drafting revised versions of the manuscript	gave critical intellectual input, and contributed in drafting revised versions of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4532809	26295033	Johann Sellner	2	contributed equally to this work	contributed equally to this work	-	-	NO
4532809	26295033	Taofiki A. Sunmonu	2	contributed equally to this work	contributed equally to this work	-	-	NO
5546801	28628941	A.D.	2	contributed to the conception and design of the study|drafted the text	contributed to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5546801	28628941	A.D.	2	contributed to the conception and design of the study|drafted the text	drafted the text	Wrote the paper	Writing - Original Draft	YES
5546801	28628941	A.R.H.	2	prepared the figures	prepared the figures	-	Visualization	YES
5546801	28628941	All authors	2	contributed to the acquisition and analysis of data	contributed to the acquisition and analysis of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5546801	28628941	D.S.	2	contributed to the conception and design of the study|drafted the text|prepared the figures|contributed equally to the article	contributed to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5546801	28628941	D.S.	2	contributed to the conception and design of the study|drafted the text|prepared the figures|contributed equally to the article	drafted the text	Wrote the paper	Writing - Original Draft	YES
5546801	28628941	D.S.	2	contributed to the conception and design of the study|drafted the text|prepared the figures|contributed equally to the article	prepared the figures	-	Visualization	YES
5546801	28628941	D.S.	2	contributed to the conception and design of the study|drafted the text|prepared the figures|contributed equally to the article	contributed equally to the article	-	-	NO
5546801	28628941	J.L.D.	2	contributed to the conception and design of the study|drafted the text|prepared the figures	contributed to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5546801	28628941	J.L.D.	2	contributed to the conception and design of the study|drafted the text|prepared the figures	drafted the text	Wrote the paper	Writing - Original Draft	YES
5546801	28628941	J.L.D.	2	contributed to the conception and design of the study|drafted the text|prepared the figures	prepared the figures	-	Visualization	YES
5546801	28628941	M.R.W.	2	contributed to the conception and design of the study|drafted the text|prepared the figures|contributed equally to the article	contributed to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5546801	28628941	M.R.W.	2	contributed to the conception and design of the study|drafted the text|prepared the figures|contributed equally to the article	drafted the text	Wrote the paper	Writing - Original Draft	YES
5546801	28628941	M.R.W.	2	contributed to the conception and design of the study|drafted the text|prepared the figures|contributed equally to the article	prepared the figures	-	Visualization	YES
5546801	28628941	M.R.W.	2	contributed to the conception and design of the study|drafted the text|prepared the figures|contributed equally to the article	contributed equally to the article	-	-	NO
5546801	28628941	M.S.	2	prepared the figures	prepared the figures	-	Visualization	YES
4408100	25905889	CK	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408100	25905889	CK	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408100	25905889	HBN	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408100	25905889	PW	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408100	25905889	PW	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408100	25905889	RK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408100	25905889	RK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408100	25905889	RK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408100	25905889	RK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408100	25905889	RK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408100	25905889	SMB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408100	25905889	SMB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408100	25905889	SMB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408100	25905889	SMB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5610682	28974956	AK	2	together designed the scope of the manuscript, wrote individual chapters, and prepared the figures	together designed the scope of the manuscript, wrote individual chapters, and prepared the figures	Conceived and designed the experiments|Wrote the paper	Visualization|Writing - Original Draft	YES
5610682	28974956	AS	2	together designed the scope of the manuscript, wrote individual chapters, and prepared the figures	together designed the scope of the manuscript, wrote individual chapters, and prepared the figures	Conceived and designed the experiments|Wrote the paper	Visualization|Writing - Original Draft	YES
5610682	28974956	MP	2	together designed the scope of the manuscript, wrote individual chapters, and prepared the figures	together designed the scope of the manuscript, wrote individual chapters, and prepared the figures	Conceived and designed the experiments|Wrote the paper	Visualization|Writing - Original Draft	YES
5610682	28974956	RJ	2	together designed the scope of the manuscript, wrote individual chapters, and prepared the figures	together designed the scope of the manuscript, wrote individual chapters, and prepared the figures	Conceived and designed the experiments|Wrote the paper	Visualization|Writing - Original Draft	YES
5610682	28974956	SK	2	together designed the scope of the manuscript, wrote individual chapters, and prepared the figures	together designed the scope of the manuscript, wrote individual chapters, and prepared the figures	Conceived and designed the experiments|Wrote the paper	Visualization|Writing - Original Draft	YES
5810317	29243388	DB	2	acquired the data, analysed and interpreted the data	acquired the data, analysed and interpreted the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5810317	29243388	IYJ	2	designed the study, drafted the initial manuscript, reviewed and critically revised and approved the final manuscript as submitted	designed the study, drafted the initial manuscript, reviewed and critically revised and approved the final manuscript as submitted	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5810317	29243388	JYC	2	conceptualized the study and is responsible for the content of the manuscript, including the data and analysis	conceptualized the study and is responsible for the content of the manuscript, including the data and analysis	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
5810317	29243388	MPL	2	provided statistical assistance and revised and approved the final manuscript	provided statistical assistance and revised and approved the final manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5810317	29243388	SK	2	provided statistical assistance and revised and approved the final manuscript	provided statistical assistance and revised and approved the final manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5810317	29243388	WWW	2	provided statistical assistance and revised and approved the final manuscript	provided statistical assistance and revised and approved the final manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5410046	28454519	All co-authors	2	significantly contributed to the present study	significantly contributed to the present study	-	-	NO
5410046	28454519	GS	2	modelling and drafted the manuscript	modelling and drafted the manuscript	Performed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5410046	28454519	JBe	2	designed the study, assisted in drafting the manuscript, and obtained funding	designed the study, assisted in drafting the manuscript, and obtained funding	Conceived and designed the experiments|Wrote the paper	Funding acquisition|Methodology|Writing - Original Draft	YES
5410046	28454519	JBo	2	designed the study, assisted in drafting the manuscript, and obtained funding	designed the study, assisted in drafting the manuscript, and obtained funding	Conceived and designed the experiments|Wrote the paper	Funding acquisition|Methodology|Writing - Original Draft	YES
5410046	28454519	MD	2	helped conceiving the study, provided access to field experiments and supervised field data collection as scientist responsible for the quebec black spruce breeding program	helped conceiving the study, provided access to field experiments and supervised field data collection as scientist responsible for the quebec black spruce breeding program	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceptualization|Investigation|Resources|Supervision	YES
5410046	28454519	SC	2	was responsible for data preparation and bioinformatics	was responsible for data preparation and bioinformatics	-	Formal analysis	YES
5410046	28454519	SDM	2	conducted the characterization of wood traits	conducted the characterization of wood traits	Performed the experiments	Investigation	YES
1762365	17183655	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762365	17183655	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762365	17183655	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762365	17183655	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762365	17183655	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762365	17183655	JN	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762365	17183655	SH	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762365	17183655	SH	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1762365	17183655	TW	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
3251038	22214386	FP	2	has made substantial contribution in reviewing the manuscript	has made substantial contribution in reviewing the manuscript	Wrote the paper	Writing - Review & Editing	YES
3251038	22214386	TB	2	has made substantial contribution in drafting the manuscript	has made substantial contribution in drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
4408101	25905862	AM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408101	25905862	AM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408101	25905862	AM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408101	25905862	DP	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408101	25905862	DP	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408101	25905862	DP	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408101	25905862	EO	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4408101	25905862	LM	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408101	25905862	LM	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408101	25905862	MG	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408101	25905862	RC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408101	25905862	RC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408101	25905862	RC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408101	25905862	RC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5601183	28556183	B.H.C.	2	were responsible for acquisition and analysis of data	were responsible for acquisition and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5601183	28556183	C.C.	2	were responsible for acquisition and analysis of data	were responsible for acquisition and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5601183	28556183	C.K.	2	were responsible for acquisition and analysis of data	were responsible for acquisition and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5601183	28556183	C.W.F.	2	were responsible for acquisition and analysis of data	were responsible for acquisition and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5601183	28556183	D.G.	2	were responsible for conception and design of the study|were responsible for acquisition and analysis of data|were responsible for drafting a significant portion of the manuscript or figures	were responsible for conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5601183	28556183	D.G.	2	were responsible for conception and design of the study|were responsible for acquisition and analysis of data|were responsible for drafting a significant portion of the manuscript or figures	were responsible for acquisition and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5601183	28556183	D.G.	2	were responsible for conception and design of the study|were responsible for acquisition and analysis of data|were responsible for drafting a significant portion of the manuscript or figures	were responsible for drafting a significant portion of the manuscript or figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5601183	28556183	E.H.	2	were responsible for acquisition and analysis of data	were responsible for acquisition and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5601183	28556183	E.R.	2	were responsible for conception and design of the study|were responsible for acquisition and analysis of data	were responsible for conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5601183	28556183	E.R.	2	were responsible for conception and design of the study|were responsible for acquisition and analysis of data	were responsible for acquisition and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5601183	28556183	F.M.	2	were responsible for conception and design of the study|were responsible for acquisition and analysis of data|were responsible for drafting a significant portion of the manuscript or figures	were responsible for conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5601183	28556183	F.M.	2	were responsible for conception and design of the study|were responsible for acquisition and analysis of data|were responsible for drafting a significant portion of the manuscript or figures	were responsible for acquisition and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5601183	28556183	F.M.	2	were responsible for conception and design of the study|were responsible for acquisition and analysis of data|were responsible for drafting a significant portion of the manuscript or figures	were responsible for drafting a significant portion of the manuscript or figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5601183	28556183	L.D.C.	2	were responsible for conception and design of the study	were responsible for conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5601183	28556183	M.P.L.	2	were responsible for acquisition and analysis of data	were responsible for acquisition and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5601183	28556183	N.E.	2	were responsible for acquisition and analysis of data	were responsible for acquisition and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5601183	28556183	O.B.T.	2	were responsible for conception and design of the study	were responsible for conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5601183	28556183	S.A.	2	were responsible for acquisition and analysis of data	were responsible for acquisition and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5601183	28556183	S.V.	2	were responsible for acquisition and analysis of data	were responsible for acquisition and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5601183	28556183	V.P.	2	were responsible for conception and design of the study|were responsible for acquisition and analysis of data|were responsible for drafting a significant portion of the manuscript or figures	were responsible for conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5601183	28556183	V.P.	2	were responsible for conception and design of the study|were responsible for acquisition and analysis of data|were responsible for drafting a significant portion of the manuscript or figures	were responsible for acquisition and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5601183	28556183	V.P.	2	were responsible for conception and design of the study|were responsible for acquisition and analysis of data|were responsible for drafting a significant portion of the manuscript or figures	were responsible for drafting a significant portion of the manuscript or figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5610699	28974954	All the authors	2	contributed to the writing of the manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5610699	28974954	EG	2	performed the data analyses	performed the data analyses	Analyzed the data	Formal analysis	YES
5610699	28974954	VR	2	performed the data analyses	performed the data analyses	Analyzed the data	Formal analysis	YES
5810318	29356365	BS	2	helped conceptualize this paper	helped conceptualize this paper	Conceived and designed the experiments	Conceptualization	YES
5810318	29356365	EM	2	helped conceptualize this paper	helped conceptualize this paper	Conceived and designed the experiments	Conceptualization	YES
5810318	29356365	GKN	2	helped conceptualize this paper	helped conceptualize this paper	Conceived and designed the experiments	Conceptualization	YES
5810318	29356365	JS	2	helped write the proposal|helped with the wrote funding proposal with	helped write the proposal	Wrote the paper	-	YES
5810318	29356365	JS	2	helped write the proposal|helped with the wrote funding proposal with	helped with the wrote funding proposal with	Wrote the paper	Funding acquisition|Writing - Original Draft	YES
5810318	29356365	PS	2	helped write the funding proposal|helped with the wrote funding proposal with	helped write the funding proposal	Wrote the paper	Funding acquisition	YES
5810318	29356365	PS	2	helped write the funding proposal|helped with the wrote funding proposal with	helped with the wrote funding proposal with	Wrote the paper	Funding acquisition|Writing - Original Draft	YES
5810318	29356365	SRF	2	project principal investigator	project principal investigator	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
5810318	29356365	TIV	2	helped write the funding proposal|helped with the wrote funding proposal with	helped write the funding proposal	Wrote the paper	Funding acquisition	YES
5810318	29356365	TIV	2	helped write the funding proposal|helped with the wrote funding proposal with	helped with the wrote funding proposal with	Wrote the paper	Funding acquisition|Writing - Original Draft	YES
5810318	29356365	TRIP	2	field operations|field operations during much of the project	field operations	Performed the experiments	Investigation	YES
5810318	29356365	TRIP	2	field operations|field operations during much of the project	field operations during much of the project	Performed the experiments	Investigation	YES
5810318	29356365	YS	2	conducted analyses of the ibbs and outreach testing data	conducted analyses of the ibbs and outreach testing data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3251040	22214546	Both authors	2	express in this letter their opinion, edited and corrected this letter and approved its final version	express in this letter their opinion, edited and corrected this letter and approved its final version	Wrote the paper	Writing - Review & Editing	YES
1762366	17183636	BK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762366	17183636	BK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762366	17183636	BK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762366	17183636	JL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762366	17183636	JL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762366	17183636	JL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762366	17183636	JL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762366	17183636	PM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762366	17183636	PM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762366	17183636	PM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762366	17183636	PM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762366	17183636	PM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762366	17183636	SM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762366	17183636	SM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762366	17183636	SM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762366	17183636	SM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5410061	28454518	All authors	2	contributed to the production of the final manuscript	contributed to the production of the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5410061	28454518	JC	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5410061	28454518	XL	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5410061	28454518	XT	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5410061	28454518	YJ	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5410061	28454518	YW	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4408103	25905726	CMR	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408103	25905726	CMR	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408103	25905726	FPR	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408103	25905726	FPR	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4408103	25905726	JLLC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408103	25905726	JLLC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408103	25905726	JLLC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408103	25905726	SH	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
3251041	22214289	AM	2	participated in design of the study and manuscript preparation	participated in design of the study and manuscript preparation	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3251041	22214289	JT	2	performed animal studies, carried out immunoassays, conceived the study and helped prepare the manuscript	performed animal studies, carried out immunoassays, conceived the study and helped prepare the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
3251041	22214289	KM	2	participated in animals studies and biochemical characterization	participated in animals studies and biochemical characterization	Performed the experiments	Investigation	YES
3251041	22214289	MG	2	carried out immunoassays, biochemical characterization, functional characterization and drafted the manuscript	carried out immunoassays, biochemical characterization, functional characterization and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3251041	22214289	TO	2	participated in animal studies and manuscript preparation	participated in animal studies and manuscript preparation	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3251041	22214289	VK	2	participated in design of the study and animal studies	participated in design of the study and animal studies	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3707220	23864824	Shuhua Yi	2	contributed to experiment design and paper revision	contributed to experiment design and paper revision	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
3707220	23864824	Yu Qin	2	contributed to field data collection, data analysis, and paper writing	contributed to field data collection, data analysis, and paper writing	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources	YES
5639357	28779545	A.M.H.	2	contributed to the conception and design of the study|contributed to the acquisition and analysis of data	contributed to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5639357	28779545	A.M.H.	2	contributed to the conception and design of the study|contributed to the acquisition and analysis of data	contributed to the acquisition and analysis of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5639357	28779545	E.H.	2	contributed to the acquisition and analysis of data|drafted the manuscript	contributed to the acquisition and analysis of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5639357	28779545	E.H.	2	contributed to the acquisition and analysis of data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5639357	28779545	E.S.R.	2	contributed to the conception and design of the study|contributed to the acquisition and analysis of data|drafted the manuscript	contributed to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5639357	28779545	E.S.R.	2	contributed to the conception and design of the study|contributed to the acquisition and analysis of data|drafted the manuscript	contributed to the acquisition and analysis of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5639357	28779545	E.S.R.	2	contributed to the conception and design of the study|contributed to the acquisition and analysis of data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5639357	28779545	H.C.	2	contributed to the conception and design of the study|contributed to the acquisition and analysis of data|drafted the manuscript	contributed to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5639357	28779545	H.C.	2	contributed to the conception and design of the study|contributed to the acquisition and analysis of data|drafted the manuscript	contributed to the acquisition and analysis of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5639357	28779545	H.C.	2	contributed to the conception and design of the study|contributed to the acquisition and analysis of data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5639357	28779545	J.C.	2	contributed to the conception and design of the study|contributed to the acquisition and analysis of data	contributed to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5639357	28779545	J.C.	2	contributed to the conception and design of the study|contributed to the acquisition and analysis of data	contributed to the acquisition and analysis of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5639357	28779545	J.J.D.	2	contributed to the conception and design of the study|contributed to the acquisition and analysis of data|drafted the manuscript	contributed to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5639357	28779545	J.J.D.	2	contributed to the conception and design of the study|contributed to the acquisition and analysis of data|drafted the manuscript	contributed to the acquisition and analysis of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5639357	28779545	J.J.D.	2	contributed to the conception and design of the study|contributed to the acquisition and analysis of data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5639357	28779545	M.S.W.	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5639357	28779545	M.W.	2	contributed to the conception and design of the study|contributed to the acquisition and analysis of data	contributed to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5639357	28779545	M.W.	2	contributed to the conception and design of the study|contributed to the acquisition and analysis of data	contributed to the acquisition and analysis of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5639357	28779545	S.J.K.	2	contributed to the conception and design of the study|contributed to the acquisition and analysis of data|drafted the manuscript	contributed to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5639357	28779545	S.J.K.	2	contributed to the conception and design of the study|contributed to the acquisition and analysis of data|drafted the manuscript	contributed to the acquisition and analysis of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5639357	28779545	S.J.K.	2	contributed to the conception and design of the study|contributed to the acquisition and analysis of data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5639357	28779545	S.R.	2	contributed to the acquisition and analysis of data	contributed to the acquisition and analysis of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5639357	28779545	V.H.	2	contributed to the conception and design of the study|contributed to the acquisition and analysis of data	contributed to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5639357	28779545	V.H.	2	contributed to the conception and design of the study|contributed to the acquisition and analysis of data	contributed to the acquisition and analysis of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
3251160	22214258	AR	2	contributed the conception and design, critically contributed and revised the manuscript and enhanced its intellectual content	contributed the conception and design, critically contributed and revised the manuscript and enhanced its intellectual content	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
3251160	22214258	HJS	2	prepared the 68 gallium and participated in writing of the manuscript	prepared the 68 gallium and participated in writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
3251160	22214258	IL	2	performed the experiments, acquired, analyzed and interpreted data and participated in writing of the manuscript	performed the experiments, acquired, analyzed and interpreted data and participated in writing of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3251160	22214258	JK	2	contributed the conception and design, critically contributed and revised the manuscript and enhanced its intellectual content	contributed the conception and design, critically contributed and revised the manuscript and enhanced its intellectual content	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
3251160	22214258	JMUS	2	contributed the conception and design, performed the experiments, analyzed and interpreted data and drafted the manuscript	contributed the conception and design, performed the experiments, analyzed and interpreted data and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
3251160	22214258	PL	2	involved in designing the experiments and revising the manuscript	involved in designing the experiments and revising the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
3251160	22214258	SY-H	2	contributed the conception and design, critically contributed and revised the manuscript and enhanced its intellectual content	contributed the conception and design, critically contributed and revised the manuscript and enhanced its intellectual content	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
3251160	22214258	VJOL	2	involved in designing the analysis and interpretation of data, and in drafting and revising the manuscript	involved in designing the analysis and interpretation of data, and in drafting and revising the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5810320	29220115	All authors	2	contributed to the writing of the manuscript and reviewed and approved the final version	contributed to the writing of the manuscript and reviewed and approved the final version	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5810320	29220115	PDG	2	advised on the interpretation of the analysis	advised on the interpretation of the analysis	Analyzed the data	Formal analysis	YES
5810320	29220115	RO	2	advised on the interpretation of the analysis	advised on the interpretation of the analysis	Analyzed the data	Formal analysis	YES
5810320	29220115	SJA	2	conceived the study and developed the methods and analysis|wrote the first draft of the manuscript	conceived the study and developed the methods and analysis	Conceived and designed the experiments|Performed the experiments	Conceptualization|Methodology	YES
5810320	29220115	SJA	2	conceived the study and developed the methods and analysis|wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
5810320	29220115	TBH	2	conceived the study and developed the methods and analysis	conceived the study and developed the methods and analysis	Conceived and designed the experiments|Performed the experiments	Conceptualization|Methodology	YES
1762367	17183659	AT	PLoS5	Conceived and designed the experiments|Reviewed and edited the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762367	17183659	AT	PLoS5	Conceived and designed the experiments|Reviewed and edited the paper	Reviewed and edited the paper	Wrote the paper	Writing - Review & Editing	YES
1762367	17183659	IN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762367	17183659	IN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762367	17183659	IN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762367	17183659	IN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762367	17183659	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762367	17183659	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1762367	17183659	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762367	17183659	US	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762367	17183659	US	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3251173	22214473	All authors	2	drafted the manuscript and read and approved the final manuscript	drafted the manuscript and read and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3251173	22214473	IL	2	conceived the study|participated in the design of the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
3251173	22214473	IL	2	conceived the study|participated in the design of the study	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
3251173	22214473	JG	2	participated in the design of the study|carried out the scannings	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
3251173	22214473	JG	2	participated in the design of the study|carried out the scannings	carried out the scannings	Performed the experiments	Investigation	YES
3251173	22214473	LH	2	participated in the design of the study	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
3251173	22214473	RP	2	performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
5610700	28974955	BH	2	designed the experiments and wrote the manuscript	designed the experiments and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5610700	28974955	JY	2	designed the experiments and wrote the manuscript|conducted the experiments	designed the experiments and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5610700	28974955	JY	2	designed the experiments and wrote the manuscript|conducted the experiments	conducted the experiments	Performed the experiments	Investigation	YES
5610700	28974955	NF	2	helped with the sample analysis	helped with the sample analysis	Analyzed the data	Formal analysis	YES
5610700	28974955	RL	2	conducted the experiments	conducted the experiments	Performed the experiments	Investigation	YES
5610700	28974955	ZY	2	arranged the experiments and did the data analysis	arranged the experiments and did the data analysis	Analyzed the data	Formal analysis	YES
5410065	28454561	All authors	2	provided valuable feedback on the manuscript and approved the paper for submission	provided valuable feedback on the manuscript and approved the paper for submission	-	-	NO
5410065	28454561	LCD	2	helped slg wrote the paper with	helped slg wrote the paper with	Wrote the paper	Writing - Original Draft	YES
5410065	28454561	SAM	2	helped slg wrote the paper with	helped slg wrote the paper with	Wrote the paper	Writing - Original Draft	YES
5410065	28454561	SLG	2	wrote the paper with	wrote the paper with	Wrote the paper	Writing - Original Draft	YES
4408104	25905713	DLL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408104	25905713	DLL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408104	25905713	DLL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408104	25905713	DLL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408104	25905713	JHT	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408104	25905713	JHT	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408104	25905713	JHT	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408104	25905713	JXJ	PLoS5	Performed the experiments|Analyzed the data|Provided language and structural improvements to manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4408104	25905713	JXJ	PLoS5	Performed the experiments|Analyzed the data|Provided language and structural improvements to manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4408104	25905713	JXJ	PLoS5	Performed the experiments|Analyzed the data|Provided language and structural improvements to manuscript	Provided language and structural improvements to manuscript	Wrote the paper	Writing - Review & Editing	YES
4408104	25905713	KHY	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408104	25905713	KHY	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5639374	28833464	A.A.H.	2	performed the acquisition and analysis of data	performed the acquisition and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5639374	28833464	All authors	2	contributed to the conception and design of the study, drafting the text, and preparing the figures	contributed to the conception and design of the study, drafting the text, and preparing the figures	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Visualization|Writing - Original Draft	YES
1762368	17183695	CA	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762368	17183695	CA	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762368	17183695	EL	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762368	17183695	EL	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762368	17183695	GB	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762368	17183695	GB	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762368	17183695	LG	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762368	17183695	LG	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762368	17183695	MO	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762368	17183695	MO	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762368	17183695	MO	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762368	17183695	MO	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762368	17183695	OM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762368	17183695	OM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762368	17183695	OM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762368	17183695	PA	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
3251208	22214377	AR	2	assisted in conducting the experiments and the analyses	assisted in conducting the experiments and the analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3251208	22214377	DD	2	assisted in the reconstructions and critically reviewed the manuscript	assisted in the reconstructions and critically reviewed the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
3251208	22214377	FG	2	performed the image reconstructions	performed the image reconstructions	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
3251208	22214377	FK	2	provided advice in the conception of the study, interpretation of the data, and critically reviewed the manuscript	provided advice in the conception of the study, interpretation of the data, and critically reviewed the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Resources|Writing - Review & Editing	YES
3251208	22214377	FMM	2	gave advice in the interpretation of the data and critically reviewed the manuscript	gave advice in the interpretation of the data and critically reviewed the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
3251208	22214377	MP	2	provided important advice in the conception of the study, performed experiments, assisted in data analysis and interpretation, and critically reviewed the manuscript	provided important advice in the conception of the study, performed experiments, assisted in data analysis and interpretation, and critically reviewed the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Resources|Writing - Review & Editing	YES
3251208	22214377	SA	2	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3251208	22214377	WL	2	was mainly involved in the conception of the study, developed the methodology, performed experiments, analyzed the data, and wrote the manuscript	was mainly involved in the conception of the study, developed the methodology, performed experiments, analyzed the data, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5611361	28979282	All authors	2	contributed critically to the drafts and approved the final version of the manuscript	contributed critically to the drafts and approved the final version of the manuscript	Wrote the paper	Writing - Original Draft	YES
5611361	28979282	FS	2	analyzed the data and wrote the first draft of the manuscript|contributed to data analysis, writing, and interpretation	analyzed the data and wrote the first draft of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5611361	28979282	FS	2	analyzed the data and wrote the first draft of the manuscript|contributed to data analysis, writing, and interpretation	contributed to data analysis, writing, and interpretation	Analyzed the data|Wrote the paper	Formal analysis	YES
5611361	28979282	G-YH	2	contributed to data analysis, writing, and interpretation	contributed to data analysis, writing, and interpretation	Analyzed the data|Wrote the paper	Formal analysis	YES
5611361	28979282	P-LF	2	carried out the experiment and collected the data	carried out the experiment and collected the data	Performed the experiments	Investigation	YES
5611361	28979282	S-BZ	2	contributed to data analysis, writing, and interpretation	contributed to data analysis, writing, and interpretation	Analyzed the data|Wrote the paper	Formal analysis	YES
5611361	28979282	Z-XF	2	carried out the experiment and collected the data|analyzed the data and wrote the first draft of the manuscript	carried out the experiment and collected the data	Performed the experiments	Investigation	YES
5611361	28979282	Z-XF	2	carried out the experiment and collected the data|analyzed the data and wrote the first draft of the manuscript	analyzed the data and wrote the first draft of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5810324	29334191	J.M.G.	2	performed and analysed some experiments	performed and analysed some experiments	Performed the experiments	Investigation	YES
5810324	29334191	M.E.G.	2	performed and analysed some experiments	performed and analysed some experiments	Performed the experiments	Investigation	YES
5810324	29334191	N.E.Q.C.	2	with all authors contributing to final version	with all authors contributing to final version	-	-	NO
4408105	25905637	FY	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408105	25905637	FY	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408105	25905637	HL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4408105	25905637	LA	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408105	25905637	LA	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408105	25905637	RW	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4408105	25905637	TL	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408105	25905637	TN	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4408105	25905637	XL	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4408105	25905637	XZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4408105	25905637	YQ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4532815	26295035	All authors	2	exchanged ideas for the review	exchanged ideas for the review	Conceived and designed the experiments	Conceptualization	YES
4532815	26295035	Bruno Daniel Correia	2	reviewed the first draft and provided comments on the references	reviewed the first draft and provided comments on the references	Wrote the paper	Writing - Original Draft	YES
4532815	26295035	Caroline Zocatelli	2	reviewed the references and prepared the first draft including the reference list	reviewed the references and prepared the first draft including the reference list	Wrote the paper	Writing - Original Draft	YES
4532815	26295035	Luciene Bruno Vieira	2	reviewed the first draft and provided comments on the references|prepared the final draft	reviewed the first draft and provided comments on the references	Wrote the paper	Writing - Original Draft	YES
4532815	26295035	Luciene Bruno Vieira	2	reviewed the first draft and provided comments on the references|prepared the final draft	prepared the final draft	Wrote the paper	Writing - Original Draft	YES
1762369	17183729	DL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762369	17183729	HP	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1762369	17183729	HP	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762369	17183729	JS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1762369	17183729	JS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762369	17183729	JS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762369	17183729	LS	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762369	17183729	MK	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762369	17183729	MK	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762369	17183729	MO	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762369	17183729	MO	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762369	17183729	MO	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762369	17183729	MO	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762369	17183729	MS	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762369	17183729	MS	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762369	17183729	PJ	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762369	17183729	RL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762369	17183729	RL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762369	17183729	RL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762369	17183729	RvC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762369	17183729	TL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762369	17183729	TS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1762369	17183729	TS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
3251252	22214535	JLT	2	performed some of the reported animal experiments, reviewed current literature, provided the concept for the review and wrote the manuscript	performed some of the reported animal experiments, reviewed current literature, provided the concept for the review and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
3251252	22214535	LLG	2	provided valuable input in the fluorescence technology and critically edited the manuscript	provided valuable input in the fluorescence technology and critically edited the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
3251252	22214535	MK	2	helped in the imaging experiments, provided valuable intellectual advice on the imaging technology and critically reviewed the manuscript	helped in the imaging experiments, provided valuable intellectual advice on the imaging technology and critically reviewed the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Investigation|Visualization|Writing - Review & Editing	YES
3251252	22214535	MWA	2	critically reviewed the manuscript and supported the conception of this review	critically reviewed the manuscript and supported the conception of this review	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
3251252	22214535	TV	2	provided some of the tissue samples for the study, gave valuable intellectual input particularly on joint disorders and critically reviewed the manuscript	provided some of the tissue samples for the study, gave valuable intellectual input particularly on joint disorders and critically reviewed the manuscript	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Review & Editing	YES
3251252	22214535	WG	2	critically reviewed the manuscript and supported the conception of this review	critically reviewed the manuscript and supported the conception of this review	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5698772	28833433	A.B.	2	participated in the acquisition and analysis of data	participated in the acquisition and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5698772	28833433	B.H.	2	contributed to the conception and design of the study|contributed to drafting the text or preparing the figures	contributed to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5698772	28833433	B.H.	2	contributed to the conception and design of the study|contributed to drafting the text or preparing the figures	contributed to drafting the text or preparing the figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5698772	28833433	C.Z.	2	participated in the acquisition and analysis of data	participated in the acquisition and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5698772	28833433	D.B.	2	participated in the acquisition and analysis of data	participated in the acquisition and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5698772	28833433	J.J.G.G.	2	contributed to the conception and design of the study|contributed to drafting the text or preparing the figures	contributed to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5698772	28833433	J.J.G.G.	2	contributed to the conception and design of the study|contributed to drafting the text or preparing the figures	contributed to drafting the text or preparing the figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5698772	28833433	J.S.K.	2	participated in the acquisition and analysis of data	participated in the acquisition and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5698772	28833433	L.E.J.	2	participated in the acquisition and analysis of data|contributed to drafting the text or preparing the figures	participated in the acquisition and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5698772	28833433	L.E.J.	2	participated in the acquisition and analysis of data|contributed to drafting the text or preparing the figures	contributed to drafting the text or preparing the figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5698772	28833433	M.M.	2	contributed to the conception and design of the study|participated in the acquisition and analysis of data|contributed to drafting the text or preparing the figures	contributed to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5698772	28833433	M.M.	2	contributed to the conception and design of the study|participated in the acquisition and analysis of data|contributed to drafting the text or preparing the figures	participated in the acquisition and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5698772	28833433	M.M.	2	contributed to the conception and design of the study|participated in the acquisition and analysis of data|contributed to drafting the text or preparing the figures	contributed to drafting the text or preparing the figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5698772	28833433	P.S.	2	participated in the acquisition and analysis of data|contributed to drafting the text or preparing the figures	participated in the acquisition and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5698772	28833433	P.S.	2	participated in the acquisition and analysis of data|contributed to drafting the text or preparing the figures	contributed to drafting the text or preparing the figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5698772	28833433	R.K.	2	participated in the acquisition and analysis of data	participated in the acquisition and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5698772	28833433	R.R.	2	contributed to the conception and design of the study|participated in the acquisition and analysis of data|contributed to drafting the text or preparing the figures	contributed to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5698772	28833433	R.R.	2	contributed to the conception and design of the study|participated in the acquisition and analysis of data|contributed to drafting the text or preparing the figures	participated in the acquisition and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5698772	28833433	R.R.	2	contributed to the conception and design of the study|participated in the acquisition and analysis of data|contributed to drafting the text or preparing the figures	contributed to drafting the text or preparing the figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5698772	28833433	V.B.	2	participated in the acquisition and analysis of data|contributed to drafting the text or preparing the figures	participated in the acquisition and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5698772	28833433	V.B.	2	participated in the acquisition and analysis of data|contributed to drafting the text or preparing the figures	contributed to drafting the text or preparing the figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5267630	28043678	All authors	2	revised it critically for important intellectual content and approved the final version of the manuscript	revised it critically for important intellectual content and approved the final version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5267630	28043678	GDL	2	contributed to the interpretation of data	contributed to the interpretation of data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5267630	28043678	LL	2	contributed to the acquisition of the data	contributed to the acquisition of the data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5267630	28043678	OP	2	contributed to the analysis of the paper	contributed to the analysis of the paper	-	-	NO
5267630	28043678	PHW	2	contributed to the interpretation of data|contributed to the acquisition of the data	contributed to the interpretation of data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5267630	28043678	PHW	2	contributed to the interpretation of data|contributed to the acquisition of the data	contributed to the acquisition of the data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5267630	28043678	SGW	2	initiated the concept and design of the paper, analysed the data and drafted the manuscript	initiated the concept and design of the paper, analysed the data and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
3251254	22214508	AR	2	conceived the study, participated in its design and coordination and critically revised the manuscript	conceived the study, participated in its design and coordination and critically revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Review & Editing	YES
3251254	22214508	HJS	2	performed the labelling chemistry and participated in in vitro studies	performed the labelling chemistry and participated in in vitro studies	Performed the experiments	Investigation	YES
3251254	22214508	PET	2	studies and drafted the manuscript	studies and drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
3251254	22214508	SJ	2	conceived the study, participated in its design and coordination and critically revised the manuscript	conceived the study, participated in its design and coordination and critically revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Review & Editing	YES
3251254	22214508	TH	2	participated in the design of the study and drafted the manuscript	participated in the design of the study and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5611366	28979281	DA	PLoS52	designed and planned the experiment	designed and planned the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5611366	28979281	JV	PLoS52	designed and planned the experiment|analyzed the data	designed and planned the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5611366	28979281	JV	PLoS52	designed and planned the experiment|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5611366	28979281	RD	PLoS52	designed and planned the experiment|performed the experiments and laboratory analyses|analyzed the data|drafted the manuscript	designed and planned the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5611366	28979281	RD	PLoS52	designed and planned the experiment|performed the experiments and laboratory analyses|analyzed the data|drafted the manuscript	performed the experiments and laboratory analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5611366	28979281	RD	PLoS52	designed and planned the experiment|performed the experiments and laboratory analyses|analyzed the data|drafted the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5611366	28979281	RD	PLoS52	designed and planned the experiment|performed the experiments and laboratory analyses|analyzed the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5611366	28979281	SB	PLoS52	designed and planned the experiment|analyzed the data	designed and planned the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5611366	28979281	SB	PLoS52	designed and planned the experiment|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5611366	28979281	SC	PLoS52	performed the experiments and laboratory analyses	performed the experiments and laboratory analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5611366	28979281	all authors	PLoS52	approved the final version to be published	approved the final version to be published	-	-	NO
5410099	28454515	FW	PLoS52	performed the experiments|designed the study and wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5410099	28454515	FW	PLoS52	performed the experiments|designed the study and wrote the manuscript	designed the study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5410099	28454515	PW	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5410099	28454515	QWY	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5410099	28454515	QYD	PLoS52	conceived the project	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5410099	28454515	YFJ	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5410099	28454515	ZJC	PLoS52	designed the study and wrote the manuscript	designed the study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5810326	29251433	Ab Schaap	2	led on programming of study tools and had over-sight of the random selection of participants and data management	led on programming of study tools and had over-sight of the random selection of participants and data management	Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Software	YES
5810326	29251433	All authors	2	contributed to the writing of the paper and have read and approved the final manuscript	contributed to the writing of the paper and have read and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5810326	29251433	Anne Stangl	2	provided expert advice to the stigma related content of the study	provided expert advice to the stigma related content of the study	-	-	NO
5810326	29251433	CM	2	were involved with leading field data collection and ensuring the quality of data	were involved with leading field data collection and ensuring the quality of data	Performed the experiments	Data curation|Investigation	YES
5810326	29251433	CMM	2	were involved with leading field data collection and ensuring the quality of data	were involved with leading field data collection and ensuring the quality of data	Performed the experiments	Data curation|Investigation	YES
5810326	29251433	GH	2	were involved with leading field data collection and ensuring the quality of data	were involved with leading field data collection and ensuring the quality of data	Performed the experiments	Data curation|Investigation	YES
5810326	29251433	HA	2	provided guidance on study design and implementation	provided guidance on study design and implementation	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Supervision	YES
5810326	29251433	RH	2	led on study design, writing the first draft and revisions of the paper, and performed statistical analysis of the data	led on study design, writing the first draft and revisions of the paper, and performed statistical analysis of the data	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5810326	29251433	Sarah Fidler	2	provided guidance on study design and implementation	provided guidance on study design and implementation	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Supervision	YES
4408106	25905629	AR	PLoS5	Wrote the paper|Study	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408106	25905629	AR	PLoS5	Wrote the paper|Study	Study	-	-	NO
4408106	25905629	BR	PLoS5	Wrote the paper|Study	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408106	25905629	BR	PLoS5	Wrote the paper|Study	Study	-	-	NO
4408106	25905629	DS	PLoS5	Wrote the paper|Study	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408106	25905629	DS	PLoS5	Wrote the paper|Study	Study	-	-	NO
4408106	25905629	KG	PLoS5	Analyzed the data|Wrote the paper|Study	Analyzed the data	Analyzed the data	Formal analysis	YES
4408106	25905629	KG	PLoS5	Analyzed the data|Wrote the paper|Study	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408106	25905629	KG	PLoS5	Analyzed the data|Wrote the paper|Study	Study	-	-	NO
4408106	25905629	MM	PLoS5	Wrote the paper|Study	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408106	25905629	MM	PLoS5	Wrote the paper|Study	Study	-	-	NO
4408106	25905629	VSG	PLoS5	Analyzed the data|Wrote the paper|Study	Analyzed the data	Analyzed the data	Formal analysis	YES
4408106	25905629	VSG	PLoS5	Analyzed the data|Wrote the paper|Study	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408106	25905629	VSG	PLoS5	Analyzed the data|Wrote the paper|Study	Study	-	-	NO
4408106	25905629	YG	PLoS5	Wrote the paper|Study	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408106	25905629	YG	PLoS5	Wrote the paper|Study	Study	-	-	NO
1762370	17183640	IZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762370	17183640	IZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762370	17183640	IZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762370	17183640	IZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762370	17183640	LY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762370	17183640	LY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762370	17183640	LY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762370	17183640	LY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762370	17183640	SK	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762370	17183640	VT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762370	17183640	VT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762370	17183640	VT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762370	17183640	VT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4532817	26295045	Cheau-Jane Peng	2	carried out the study design, data analysis and interpretation, and paper drafting	carried out the study design, data analysis and interpretation, and paper drafting	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4532817	26295045	Cheng-Yao Lin	2	was responsible for data interpretation and paper revision	was responsible for data interpretation and paper revision	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4532817	26295045	How-Ran Guo	2	was in charge of study supervision, data analysis and interpretation, and paper revision	was in charge of study supervision, data analysis and interpretation, and paper revision	Analyzed the data|Wrote the paper	Formal analysis|Supervision|Writing - Review & Editing	YES
3251329	22214344	All authors	2	accept full responsibility for the accuracy of the raw data and data analysis, and exercised authority in manuscript preparation and the decision to submit the manuscript for publication	accept full responsibility for the accuracy of the raw data and data analysis, and exercised authority in manuscript preparation and the decision to submit the manuscript for publication	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3251329	22214344	HO	2	is the co-pi of this study and involved in the design and interpretation of the analysis as well as in writing manuscript	is the co-pi of this study and involved in the design and interpretation of the analysis as well as in writing manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3251329	22214344	KK	2	designed and performed all animal experiments, analyzed the data, and wrote the manuscript	designed and performed all animal experiments, analyzed the data, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
3251329	22214344	MG	2	performed tyrosine hydroxylase immunohistochemical study	performed tyrosine hydroxylase immunohistochemical study	Performed the experiments	Investigation	YES
3251329	22214344	TK	2	assisted in conducting rotational behavior test and gave valuable input on biological aspects	assisted in conducting rotational behavior test and gave valuable input on biological aspects	Performed the experiments	Investigation	YES
3251329	22214344	TT	2	helped the study design, animal experiments, and kinetic analysis and critically reviewed the manuscript	helped the study design, animal experiments, and kinetic analysis and critically reviewed the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
3251329	22214344	YKat	2	helped animal experiments, radio-metabolite analysis, and monoamine quantitation	helped animal experiments, radio-metabolite analysis, and monoamine quantitation	Performed the experiments	Investigation	YES
3251329	22214344	YKuw	2	provided intellectual input, performed data quality assurance of all the experiments	provided intellectual input, performed data quality assurance of all the experiments	Performed the experiments|Contributed reagents/materials/analysis tools	Data curation|Resources|Validation	YES
3251329	22214344	YWad	2	helped perform pet scan and image reconstruction	helped perform pet scan and image reconstruction	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
3251329	22214344	YWat	2	is the pi of the study and is involved in all aspects of this work from design to writing and approving the final content of the manuscript	is the pi of the study and is involved in all aspects of this work from design to writing and approving the final content of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5698802	28976605	A.A.	2	drafted the manuscript and figures, and all authors approved the final version	drafted the manuscript and figures, and all authors approved the final version	Wrote the paper	Visualization|Writing - Original Draft	YES
5698802	28976605	A.B.	2	contributed to the concept and study design|drafted the manuscript and figures, and all authors approved the final version	contributed to the concept and study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5698802	28976605	A.B.	2	contributed to the concept and study design|drafted the manuscript and figures, and all authors approved the final version	drafted the manuscript and figures, and all authors approved the final version	Wrote the paper	Visualization|Writing - Original Draft	YES
5698802	28976605	All authors	2	contributed to data acquisition and analysis	contributed to data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5698802	28976605	B.B.	2	contributed to the concept and study design|drafted the manuscript and figures, and all authors approved the final version	contributed to the concept and study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5698802	28976605	B.B.	2	contributed to the concept and study design|drafted the manuscript and figures, and all authors approved the final version	drafted the manuscript and figures, and all authors approved the final version	Wrote the paper	Visualization|Writing - Original Draft	YES
5698802	28976605	E.D.G.	2	contributed to the concept and study design	contributed to the concept and study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5698802	28976605	M.M.	2	drafted the manuscript and figures, and all authors approved the final version	drafted the manuscript and figures, and all authors approved the final version	Wrote the paper	Visualization|Writing - Original Draft	YES
4408107	25906365	AN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408107	25906365	AN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408107	25906365	AN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408107	25906365	AN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408107	25906365	CR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408107	25906365	CR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408107	25906365	CR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408107	25906365	CR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408107	25906365	ED	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408107	25906365	ED	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408107	25906365	JB	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408107	25906365	JB	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408107	25906365	JF	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408107	25906365	JF	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408107	25906365	ST	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408107	25906365	ST	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408107	25906365	ST	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408107	25906365	WS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408107	25906365	WS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5810327	29098809	EK	2	enrolled patients	enrolled patients	Performed the experiments	Investigation	YES
5810327	29098809	LD	2	designed and supervised the study protocol|enrolled patients	designed and supervised the study protocol	Conceived and designed the experiments	Methodology|Supervision	YES
5810327	29098809	LD	2	designed and supervised the study protocol|enrolled patients	enrolled patients	Performed the experiments	Investigation	YES
5810327	29098809	LL	2	conducted laboratory assays|analysed data	conducted laboratory assays	Performed the experiments	Investigation	YES
5810327	29098809	LL	2	conducted laboratory assays|analysed data	analysed data	Analyzed the data	Formal analysis	YES
5810327	29098809	MC	2	conceived and developed the study and wrote the manuscript|conducted laboratory assays|analysed data	conceived and developed the study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5810327	29098809	MC	2	conceived and developed the study and wrote the manuscript|conducted laboratory assays|analysed data	conducted laboratory assays	Performed the experiments	Investigation	YES
5810327	29098809	MC	2	conceived and developed the study and wrote the manuscript|conducted laboratory assays|analysed data	analysed data	Analyzed the data	Formal analysis	YES
5810327	29098809	MO	2	conducted laboratory assays	conducted laboratory assays	Performed the experiments	Investigation	YES
5810327	29098809	RK	2	conceived and developed the study and wrote the manuscript|designed and supervised the study protocol	conceived and developed the study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5810327	29098809	RK	2	conceived and developed the study and wrote the manuscript|designed and supervised the study protocol	designed and supervised the study protocol	Conceived and designed the experiments	Methodology|Supervision	YES
1762371	17183676	AD	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1762371	17183676	AS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1762371	17183676	HW	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762371	17183676	JY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762371	17183676	JY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762371	17183676	JY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762371	17183676	JY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762371	17183676	XH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762371	17183676	XH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762371	17183676	XH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762371	17183676	YC	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762371	17183676	YC	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762371	17183676	YY	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
3251512	22214423	All the authors	2	gave their final approval for publication	gave their final approval for publication	-	-	NO
3251512	22214423	GA	2	has been involved in the study design and in revising the manuscript	has been involved in the study design and in revising the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
3251512	22214423	JOP	2	has been involved in the study design, data acquisition, analysis and interpretation, and in revising the manuscript	has been involved in the study design, data acquisition, analysis and interpretation, and in revising the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Review & Editing	YES
3251512	22214423	JR	2	has been involved in the study design, data acquisition and interpretation, and in revising the manuscript	has been involved in the study design, data acquisition and interpretation, and in revising the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Review & Editing	YES
3251512	22214423	PI	2	has been involved in data acquisition and in revising the manuscript	has been involved in data acquisition and in revising the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
3251512	22214423	RWJ	2	has been involved in the study design, data acquisition, and in revising the manuscript	has been involved in the study design, data acquisition, and in revising the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
3251512	22214423	VD	2	has been involved in data acquisition, analysis and interpretation, in drafting and revising the manuscript	has been involved in data acquisition, analysis and interpretation, in drafting and revising the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5483229	28366472	AR	2	conceived of and designed the refer study|were grant applicants|was the study statistician	conceived of and designed the refer study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5483229	28366472	AR	2	conceived of and designed the refer study|were grant applicants|was the study statistician	were grant applicants	-	-	NO
5483229	28366472	AR	2	conceived of and designed the refer study|were grant applicants|was the study statistician	was the study statistician	Analyzed the data	Formal analysis	YES
5483229	28366472	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5483229	28366472	CT	2	were grant applicants|provided clinical input throughout the study|contributed to the writing of the manuscript	were grant applicants	-	-	NO
5483229	28366472	CT	2	were grant applicants|provided clinical input throughout the study|contributed to the writing of the manuscript	provided clinical input throughout the study	-	-	NO
5483229	28366472	CT	2	were grant applicants|provided clinical input throughout the study|contributed to the writing of the manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5483229	28366472	DM	2	was study co-ordinator for part of the study	was study co-ordinator for part of the study	-	Project administration	YES
5483229	28366472	GS	2	towards the end of the study	towards the end of the study	-	-	NO
5483229	28366472	JD	2	were grant applicants	were grant applicants	-	-	NO
5483229	28366472	JM	2	conceived of and designed the refer study|were grant applicants	conceived of and designed the refer study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5483229	28366472	JM	2	conceived of and designed the refer study|were grant applicants	were grant applicants	-	-	NO
5483229	28366472	LT	2	conceived of and designed the refer study|were grant applicants|was senior study co-ordinator for most of the study	conceived of and designed the refer study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5483229	28366472	LT	2	conceived of and designed the refer study|were grant applicants|was senior study co-ordinator for most of the study	were grant applicants	-	-	NO
5483229	28366472	LT	2	conceived of and designed the refer study|were grant applicants|was senior study co-ordinator for most of the study	was senior study co-ordinator for most of the study	-	Project administration	YES
5483229	28366472	MC	2	conceived of and designed the refer study|were grant applicants	conceived of and designed the refer study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5483229	28366472	MC	2	conceived of and designed the refer study|were grant applicants	were grant applicants	-	-	NO
5483229	28366472	MM	2	conducted the health economic evaluation|drafted the first manuscript|is the guarantor	conducted the health economic evaluation	Performed the experiments	Investigation	YES
5483229	28366472	MM	2	conducted the health economic evaluation|drafted the first manuscript|is the guarantor	drafted the first manuscript	Wrote the paper	Writing - Original Draft	YES
5483229	28366472	MM	2	conducted the health economic evaluation|drafted the first manuscript|is the guarantor	is the guarantor	-	-	NO
5483229	28366472	PB	2	was the main supervisor of this analysis|were grant applicants|was health economist on the study|contributed to the writing of the manuscript	was the main supervisor of this analysis	-	Supervision	YES
5483229	28366472	PB	2	was the main supervisor of this analysis|were grant applicants|was health economist on the study|contributed to the writing of the manuscript	were grant applicants	-	-	NO
5483229	28366472	PB	2	was the main supervisor of this analysis|were grant applicants|was health economist on the study|contributed to the writing of the manuscript	was health economist on the study	-	-	NO
5483229	28366472	PB	2	was the main supervisor of this analysis|were grant applicants|was health economist on the study|contributed to the writing of the manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5483229	28366472	RH	2	conceived of and designed the refer study|were grant applicants|provided clinical input throughout the study|contributed to the writing of the manuscript	conceived of and designed the refer study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5483229	28366472	RH	2	conceived of and designed the refer study|were grant applicants|provided clinical input throughout the study|contributed to the writing of the manuscript	were grant applicants	-	-	NO
5483229	28366472	RH	2	conceived of and designed the refer study|were grant applicants|provided clinical input throughout the study|contributed to the writing of the manuscript	provided clinical input throughout the study	-	-	NO
5483229	28366472	RH	2	conceived of and designed the refer study|were grant applicants|provided clinical input throughout the study|contributed to the writing of the manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5483229	28366472	RI	2	was study co-ordinator throughout the study	was study co-ordinator throughout the study	-	Project administration	YES
5725696	29023963	F.A.W.	1	Conception and design of the study	Conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5725696	29023963	N.v.V.	1	Conception and design of the study	Conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5725696	29023963	S.C.M.N.	1	Conception and design of the study	Conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5725696	29023963	S.J.G.K.	1	Conception and design of the study	Conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5725696	29023963	all authors	1	Data acquisition and analysis	Data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5412052	28464824	AC	2	provided insight into physiological interpretations of analyses and contributed to manuscript sections	provided insight into physiological interpretations of analyses and contributed to manuscript sections	Analyzed the data	Formal analysis	YES
5412052	28464824	ALA	2	conceived and designed this study|extracted rna from tissue samples|performed all gene expression, pathway, and regulatory molecule analyses|wrote the manuscript	conceived and designed this study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5412052	28464824	ALA	2	conceived and designed this study|extracted rna from tissue samples|performed all gene expression, pathway, and regulatory molecule analyses|wrote the manuscript	extracted rna from tissue samples	Performed the experiments	Investigation	YES
5412052	28464824	ALA	2	conceived and designed this study|extracted rna from tissue samples|performed all gene expression, pathway, and regulatory molecule analyses|wrote the manuscript	performed all gene expression, pathway, and regulatory molecule analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5412052	28464824	ALA	2	conceived and designed this study|extracted rna from tissue samples|performed all gene expression, pathway, and regulatory molecule analyses|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5412052	28464824	All authors	2	read, edited, and approved the final manuscript	read, edited, and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5412052	28464824	BWP	2	performed all gene expression, pathway, and regulatory molecule analyses|wrote the manuscript	performed all gene expression, pathway, and regulatory molecule analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5412052	28464824	BWP	2	performed all gene expression, pathway, and regulatory molecule analyses|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5412052	28464824	DCC	2	extracted rna from tissue samples	extracted rna from tissue samples	Performed the experiments	Investigation	YES
5412052	28464824	DRS	2	extracted rna from tissue samples	extracted rna from tissue samples	Performed the experiments	Investigation	YES
5412052	28464824	RPR	2	provided insight into physiological interpretations of analyses and contributed to manuscript sections	provided insight into physiological interpretations of analyses and contributed to manuscript sections	Analyzed the data	Formal analysis	YES
5412052	28464824	SEM	2	provided insight into physiological interpretations of analyses and contributed to manuscript sections	provided insight into physiological interpretations of analyses and contributed to manuscript sections	Analyzed the data	Formal analysis	YES
5412052	28464824	SMS	2	conceived and designed this study|performed feeding experiments and tissue sampling	conceived and designed this study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5412052	28464824	SMS	2	conceived and designed this study|performed feeding experiments and tissue sampling	performed feeding experiments and tissue sampling	Performed the experiments	Investigation	YES
5412052	28464824	TAC	2	conceived and designed this study|extracted rna from tissue samples|wrote the manuscript	conceived and designed this study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5412052	28464824	TAC	2	conceived and designed this study|extracted rna from tissue samples|wrote the manuscript	extracted rna from tissue samples	Performed the experiments	Investigation	YES
5412052	28464824	TAC	2	conceived and designed this study|extracted rna from tissue samples|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4408108	25906356	AC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408108	25906356	AC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408108	25906356	AC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408108	25906356	AC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408108	25906356	AF	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4408108	25906356	AF	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4408108	25906356	DU	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408108	25906356	DU	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408108	25906356	ES	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408108	25906356	ES	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408108	25906356	JD	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408108	25906356	JD	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408108	25906356	JL	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4408108	25906356	JL	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4408108	25906356	NM	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408108	25906356	NM	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5611372	28979278	AP	2	supervised the hydraulic modeling and reviewed the manuscript	supervised the hydraulic modeling and reviewed the manuscript	Performed the experiments|Wrote the paper	Methodology|Supervision|Writing - Review & Editing	YES
5611372	28979278	GE	2	supervised the ecological interpretation of the results and reviewed the manuscript	supervised the ecological interpretation of the results and reviewed the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Supervision|Writing - Review & Editing	YES
5611372	28979278	RR	2	established the experimental design, conducted the experiment, analyzed data and wrote the manuscript	established the experimental design, conducted the experiment, analyzed data and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5611372	28979278	TF	2	was the main supervisor and reviewed the manuscript	was the main supervisor and reviewed the manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
3261093	22214419	Both authors	2	wrote and approved the final manuscript	wrote and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3261093	22214419	DFS	2	performed the experiments and statistical analyses	performed the experiments and statistical analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3261093	22214419	OLM	2	implemented the kinetic models and performed the kinetic analyses	implemented the kinetic models and performed the kinetic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
1762372	17183680	AM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1762372	17183680	AM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762372	17183680	DU	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762372	17183680	DU	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762372	17183680	DU	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762372	17183680	KE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762372	17183680	KE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762372	17183680	KE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762372	17183680	KE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762372	17183680	LV	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762372	17183680	MS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762372	17183680	MT	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5810329	29356390	All authors	2	contributed extensively to the work presented in this paper	contributed extensively to the work presented in this paper	-	-	NO
5810329	29356390	JMC	2	conceived the study|drafted the manuscript, and all the other authors contributed substantially to the writing and revising of the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5810329	29356390	JMC	2	conceived the study|drafted the manuscript, and all the other authors contributed substantially to the writing and revising of the manuscript	drafted the manuscript, and all the other authors contributed substantially to the writing and revising of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5810329	29356390	LEC	2	performed the statistical analyses, and all authors interpreted the data	performed the statistical analyses, and all authors interpreted the data	Analyzed the data	Formal analysis	YES
5810329	29356390	PML	2	conceived the study|supervised the process|performed the statistical analyses, and all authors interpreted the data	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5810329	29356390	PML	2	conceived the study|supervised the process|performed the statistical analyses, and all authors interpreted the data	supervised the process	-	Supervision	YES
5810329	29356390	PML	2	conceived the study|supervised the process|performed the statistical analyses, and all authors interpreted the data	performed the statistical analyses, and all authors interpreted the data	Analyzed the data	Formal analysis	YES
5810329	29356390	TST	2	conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
3265412	22214469	AVDL	PLoS52	critically contributed to the manuscript	critically contributed to the manuscript	-	-	NO
3265412	22214469	All authors	PLoS52	contributed substantially to the scientific process leading to this manuscript	contributed substantially to the scientific process leading to this manuscript	-	-	NO
3265412	22214469	BADW	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
3265412	22214469	BB	PLoS52	acquired data on the control subjects|critically contributed to the manuscript	acquired data on the control subjects	Performed the experiments	Investigation	YES
3265412	22214469	BB	PLoS52	acquired data on the control subjects|critically contributed to the manuscript	critically contributed to the manuscript	-	-	NO
3265412	22214469	EB	PLoS52	acquired data on the control subjects|critically contributed to the manuscript	acquired data on the control subjects	Performed the experiments	Investigation	YES
3265412	22214469	EB	PLoS52	acquired data on the control subjects|critically contributed to the manuscript	critically contributed to the manuscript	-	-	NO
3265412	22214469	EF	PLoS52	contributed to the concept and design of the study	contributed to the concept and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3265412	22214469	EVDG	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
3265412	22214469	JB	PLoS52	contributed to the concept and design of the study	contributed to the concept and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3265412	22214469	MJS	PLoS52	contributed to the concept and design of the study|critically contributed to the manuscript	contributed to the concept and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3265412	22214469	MJS	PLoS52	contributed to the concept and design of the study|critically contributed to the manuscript	critically contributed to the manuscript	-	-	NO
3265412	22214469	TAVA	PLoS52	acquired data on the control subjects|critically contributed to the manuscript	acquired data on the control subjects	Performed the experiments	Investigation	YES
3265412	22214469	TAVA	PLoS52	acquired data on the control subjects|critically contributed to the manuscript	critically contributed to the manuscript	-	-	NO
5611396	28979284	M. The	2	paper was written and edited by the three authors	paper was written and edited by the three authors	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4408111	25906052	CY	PLoS5	Collected clinical information and performed endoscopy	Collected clinical information and performed endoscopy	Performed the experiments	Investigation	YES
4408111	25906052	HO	PLoS5	Collected clinical information and performed endoscopy	Collected clinical information and performed endoscopy	Performed the experiments	Investigation	YES
4408111	25906052	JA	PLoS5	Collected clinical information and performed endoscopy	Collected clinical information and performed endoscopy	Performed the experiments	Investigation	YES
4408111	25906052	K. Sakamoto	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4408111	25906052	K. Sekine	PLoS5	Collected clinical information and performed endoscopy	Collected clinical information and performed endoscopy	Performed the experiments	Investigation	YES
4408111	25906052	KW	PLoS5	Collected clinical information and performed endoscopy	Collected clinical information and performed endoscopy	Performed the experiments	Investigation	YES
4408111	25906052	MN	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408111	25906052	MS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4408111	25906052	MY	PLoS5	Collected clinical information and performed endoscopy	Collected clinical information and performed endoscopy	Performed the experiments	Investigation	YES
4408111	25906052	NI	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408111	25906052	NN	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408111	25906052	NN	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408111	25906052	NN	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408111	25906052	NU	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408111	25906052	RN	PLoS5	Collected clinical information and performed endoscopy	Collected clinical information and performed endoscopy	Performed the experiments	Investigation	YES
4408111	25906052	T. Sakurai	PLoS5	Collected clinical information and performed endoscopy	Collected clinical information and performed endoscopy	Performed the experiments	Investigation	YES
4408111	25906052	T. Shimbo	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4408111	25906052	TA	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1762373	17183715	AM	PLoS5	Contributed reagents/materials/analysis tools|Patient selection, recruitment and data collection	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762373	17183715	AM	PLoS5	Contributed reagents/materials/analysis tools|Patient selection, recruitment and data collection	Patient selection, recruitment and data collection	Performed the experiments	Investigation	YES
1762373	17183715	CB	PLoS5	Contributed reagents/materials/analysis tools|Patient selection, recruitment and data collection	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762373	17183715	CB	PLoS5	Contributed reagents/materials/analysis tools|Patient selection, recruitment and data collection	Patient selection, recruitment and data collection	Performed the experiments	Investigation	YES
1762373	17183715	DG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762373	17183715	DG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762373	17183715	DG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762373	17183715	ET	PLoS5	Contributed reagents/materials/analysis tools|Molecular biology, subsequent data and manuscript discussion	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762373	17183715	ET	PLoS5	Contributed reagents/materials/analysis tools|Molecular biology, subsequent data and manuscript discussion	Molecular biology, subsequent data and manuscript discussion	Performed the experiments	Investigation	YES
1762373	17183715	FP	PLoS5	Contributed reagents/materials/analysis tools|Patient selection, recruitment and data collection, subsequent manuscript discussion	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762373	17183715	FP	PLoS5	Contributed reagents/materials/analysis tools|Patient selection, recruitment and data collection, subsequent manuscript discussion	Patient selection, recruitment and data collection, subsequent manuscript discussion	Performed the experiments	Investigation	YES
1762373	17183715	GF	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762373	17183715	GV	PLoS5	Contributed reagents/materials/analysis tools|Patient selection, recruitment and data collection	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762373	17183715	GV	PLoS5	Contributed reagents/materials/analysis tools|Patient selection, recruitment and data collection	Patient selection, recruitment and data collection	Performed the experiments	Investigation	YES
1762373	17183715	IT	PLoS5	Contributed reagents/materials/analysis tools|Patient selection, recruitment and data collection	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762373	17183715	IT	PLoS5	Contributed reagents/materials/analysis tools|Patient selection, recruitment and data collection	Patient selection, recruitment and data collection	Performed the experiments	Investigation	YES
1762373	17183715	NM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762373	17183715	NM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762373	17183715	NM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762373	17183715	OO	PLoS5	Contributed reagents/materials/analysis tools|Patient selection, recruitment and data collection, subsequent manuscript discussion|Critical review of the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762373	17183715	OO	PLoS5	Contributed reagents/materials/analysis tools|Patient selection, recruitment and data collection, subsequent manuscript discussion|Critical review of the paper	Patient selection, recruitment and data collection, subsequent manuscript discussion	Performed the experiments	Investigation	YES
1762373	17183715	OO	PLoS5	Contributed reagents/materials/analysis tools|Patient selection, recruitment and data collection, subsequent manuscript discussion|Critical review of the paper	Critical review of the paper	Wrote the paper	Writing - Review & Editing	YES
1762373	17183715	PG	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762373	17183715	PP	PLoS5	Contributed reagents/materials/analysis tools|Molecular biology, subsequent data and manuscript discussion	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762373	17183715	PP	PLoS5	Contributed reagents/materials/analysis tools|Molecular biology, subsequent data and manuscript discussion	Molecular biology, subsequent data and manuscript discussion	Performed the experiments	Investigation	YES
1762373	17183715	RC	PLoS5	Collection, subsequent manuscript discussion|Critical review of the paper	Collection, subsequent manuscript discussion	-	-	NO
1762373	17183715	RC	PLoS5	Collection, subsequent manuscript discussion|Critical review of the paper	Critical review of the paper	Wrote the paper	Writing - Review & Editing	YES
1762373	17183715	SF	PLoS5	Contributed reagents/materials/analysis tools|Patient selection, recruitment and data collection, subsequent manuscript discussion	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762373	17183715	SF	PLoS5	Contributed reagents/materials/analysis tools|Patient selection, recruitment and data collection, subsequent manuscript discussion	Patient selection, recruitment and data collection, subsequent manuscript discussion	Performed the experiments	Investigation	YES
1762373	17183715	VL	PLoS5	Contributed reagents/materials/analysis tools|Patient selection, recruitment and data collection	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762373	17183715	VL	PLoS5	Contributed reagents/materials/analysis tools|Patient selection, recruitment and data collection	Patient selection, recruitment and data collection	Performed the experiments	Investigation	YES
3271392	22214480	AE	2	initiated the idea to use ts1 in the sclc and got1 xenografts|performed the immunohistochemistry and the interpretation of the histological results, calculation of mouse and tumour cells and drafted the manuscript	initiated the idea to use ts1 in the sclc and got1 xenografts	Conceived and designed the experiments	Conceptualization	YES
3271392	22214480	AE	2	initiated the idea to use ts1 in the sclc and got1 xenografts|performed the immunohistochemistry and the interpretation of the histological results, calculation of mouse and tumour cells and drafted the manuscript	performed the immunohistochemistry and the interpretation of the histological results, calculation of mouse and tumour cells and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3271392	22214480	EFA	2	conceived the animal study, and helped to draft the manuscript	conceived the animal study, and helped to draft the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
3271392	22214480	PB	2	initiated the idea to use ts1 in the sclc and got1 xenografts|conceived the animal study, and helped to draft the manuscript	initiated the idea to use ts1 in the sclc and got1 xenografts	Conceived and designed the experiments	Conceptualization	YES
3271392	22214480	PB	2	initiated the idea to use ts1 in the sclc and got1 xenografts|conceived the animal study, and helped to draft the manuscript	conceived the animal study, and helped to draft the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
3271392	22214480	TS	2	performed the study with biopsies from primary small-cell lung carcinoma and was involved in the interpretation of the histological result as well as reading and approval of the final manuscript	performed the study with biopsies from primary small-cell lung carcinoma and was involved in the interpretation of the histological result as well as reading and approval of the final manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
5725735	28981963	C.R.	1	Conception and design of the study	Conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5725735	28981963	H.Z.	1	Conception and design of the study	Conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5725735	28981963	K.B.	1	Conception and design of the study	Conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5725735	28981963	N.M.	1	Conception and design of the study	Conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5725735	28981963	N.N.	1	Conception and design of the study	Conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5725735	28981963	T.C.	1	Conception and design of the study	Conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5725735	28981963	all authors	1	Data acquisition and analysis	Data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5810330	29356376	All authors	2	reviewed and provided revisions to the draft	reviewed and provided revisions to the draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5810330	29356376	BRP	2	conceived the topic for the commentary	conceived the topic for the commentary	Conceived and designed the experiments	Conceptualization	YES
5810330	29356376	DS	2	developed the initial outline and draft	developed the initial outline and draft	Wrote the paper	Writing - Original Draft	YES
5810330	29356376	LNB	2	developed the initial outline and draft	developed the initial outline and draft	Wrote the paper	Writing - Original Draft	YES
5810330	29356376	MS	2	developed the initial outline and draft|incorporated revisions and coordinated approval from all authors prior to submission	developed the initial outline and draft	Wrote the paper	Writing - Original Draft	YES
5810330	29356376	MS	2	developed the initial outline and draft|incorporated revisions and coordinated approval from all authors prior to submission	incorporated revisions and coordinated approval from all authors prior to submission	Wrote the paper	Project administration|Writing - Review & Editing	YES
5810330	29356376	SM	2	conceived the topic for the commentary	conceived the topic for the commentary	Conceived and designed the experiments	Conceptualization	YES
3087214	21552415	All authors	2	have made some contributions to the text of the manuscript	have made some contributions to the text of the manuscript	Wrote the paper	Writing - Original Draft	YES
5412055	28464870	REPET	2	analyses, bioinformatics assistance and support	analyses, bioinformatics assistance and support	Analyzed the data	Formal analysis	YES
5412055	28464870	TE	2	flanking distances analysis	flanking distances analysis	-	-	NO
5412055	28464870	WGS	2	rna seq	rna seq	Performed the experiments	Investigation	YES
3710604	23878522	Ferreira Neto	2	contributed equally to this work	contributed equally to this work	-	-	NO
3710604	23878522	Jose Ribamar Costa	2	contributed equally to this work	contributed equally to this work	-	-	NO
3710604	23878522	Suzana de Aragao Britto-Kido	2	contributed equally to this work	contributed equally to this work	-	-	NO
4408112	25905816	BM	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408112	25905816	BM	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408112	25905816	MD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408112	25905816	MD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408112	25905816	MD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408112	25905816	MD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408112	25905816	RBDT	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408112	25905816	RBDT	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3274480	22251281	AAL	2	was involved in the study design and helped in drafting the manuscript	was involved in the study design and helped in drafting the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3274480	22251281	ADW	2	was involved in the tracer production and quality control of tracer production processes	was involved in the tracer production and quality control of tracer production processes	Performed the experiments	Validation	YES
3274480	22251281	BNMvB	2	supervised the pet data acquisition and helped in drafting the manuscript	supervised the pet data acquisition and helped in drafting the manuscript	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Original Draft	YES
3274480	22251281	DMEvA	2	performed the pet studies and data analysis and wrote the manuscript	performed the pet studies and data analysis and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3274480	22251281	ML	2	was involved in the model development and data processing	was involved in the model development and data processing	Performed the experiments|Analyzed the data	Data curation|Methodology	YES
3274480	22251281	PS	2	helped in drafting the manuscript	helped in drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
3274480	22251281	RB	2	was involved in the quality control of pet data	was involved in the quality control of pet data	Performed the experiments	Validation	YES
3274480	22251281	RCS	2	performed the metabolite analysis and quality control of the tracer	performed the metabolite analysis and quality control of the tracer	Performed the experiments	Investigation|Validation	YES
4534591	26295037	Heon Sang Lee	2	provided intellectual input and contributed to the writing of the paper	provided intellectual input and contributed to the writing of the paper	Wrote the paper	Writing - Original Draft	YES
4534591	26295037	Il Je Yu	2	initiated, designed, and directed all the experiments|provided intellectual input and contributed to the writing of the paper	initiated, designed, and directed all the experiments	Conceived and designed the experiments	Conceptualization|Methodology|Supervision	YES
4534591	26295037	Il Je Yu	2	initiated, designed, and directed all the experiments|provided intellectual input and contributed to the writing of the paper	provided intellectual input and contributed to the writing of the paper	Wrote the paper	Writing - Original Draft	YES
4534591	26295037	Jae Hoon Shin	2	collected and analyzed the biological samples	collected and analyzed the biological samples	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4534591	26295037	Ji Hyun Lee	2	conducted the sampling and analysis of the workplace air samples	conducted the sampling and analysis of the workplace air samples	Performed the experiments	Investigation	YES
4534591	26295037	Jin Kwon Kim	2	collected and analyzed the biological samples	collected and analyzed the biological samples	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4534591	26295037	Jong Seong Lee	2	collected and analyzed the biological samples	collected and analyzed the biological samples	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4534591	26295037	Kangho Ahn	2	conducted the sampling and analysis of the workplace air samples	conducted the sampling and analysis of the workplace air samples	Performed the experiments	Investigation	YES
4534591	26295037	Keun Soo Kim	2	provided intellectual input and contributed to the writing of the paper	provided intellectual input and contributed to the writing of the paper	Wrote the paper	Writing - Original Draft	YES
4534591	26295037	Nam Woong Song	2	provided intellectual input and contributed to the writing of the paper	provided intellectual input and contributed to the writing of the paper	Wrote the paper	Writing - Original Draft	YES
4534591	26295037	Sung Gu Han	2	initiated, designed, and directed all the experiments	initiated, designed, and directed all the experiments	Conceived and designed the experiments	Conceptualization|Methodology|Supervision	YES
4534591	26295037	Tae-Gyu Kim	2	collected and analyzed the biological samples	collected and analyzed the biological samples	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5611414	28979283	JM	2	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5611414	28979283	The authors	2	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	Performed the experiments	Investigation	YES
5611414	28979283	WC	2	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5611414	28979283	XL	2	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5611414	28979283	XY	2	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5611414	28979283	YE	2	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5414149	28464795	EA	2	performed qpcr analysis on trout and lamprey samples	performed qpcr analysis on trout and lamprey samples	Performed the experiments	Investigation	YES
5414149	28464795	EPJ	2	performed qpcr analysis on trout and lamprey samples|contributed to the manuscript correction	performed qpcr analysis on trout and lamprey samples	Performed the experiments	Investigation	YES
5414149	28464795	EPJ	2	performed qpcr analysis on trout and lamprey samples|contributed to the manuscript correction	contributed to the manuscript correction	Wrote the paper	Writing - Review & Editing	YES
5414149	28464795	JB	2	supervised in silico analysis|contributed to the manuscript correction	supervised in silico analysis	-	Formal analysis|Supervision	YES
5414149	28464795	JB	2	supervised in silico analysis|contributed to the manuscript correction	contributed to the manuscript correction	Wrote the paper	Writing - Review & Editing	YES
5414149	28464795	JLS	2	contributed to the manuscript correction	contributed to the manuscript correction	Wrote the paper	Writing - Review & Editing	YES
5414149	28464795	LM	2	conceived and managed the study, performed lamprey tissues collection and in silico analysis and wrote the manuscript|the discussion concerning g6pc expression in trout brain|contributed to the manuscript correction	conceived and managed the study, performed lamprey tissues collection and in silico analysis and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Formal analysis|Investigation|Project administration|Writing - Original Draft	YES
5414149	28464795	LM	2	conceived and managed the study, performed lamprey tissues collection and in silico analysis and wrote the manuscript|the discussion concerning g6pc expression in trout brain|contributed to the manuscript correction	the discussion concerning g6pc expression in trout brain	Performed the experiments	Investigation	YES
5414149	28464795	LM	2	conceived and managed the study, performed lamprey tissues collection and in silico analysis and wrote the manuscript|the discussion concerning g6pc expression in trout brain|contributed to the manuscript correction	contributed to the manuscript correction	Wrote the paper	Writing - Review & Editing	YES
5414149	28464795	SP	2	contributed to the manuscript correction	contributed to the manuscript correction	Wrote the paper	Writing - Review & Editing	YES
5725816	29059709	A.B.	2	were responsible for data acquisition and analysis	were responsible for data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5725816	29059709	All authors	2	have read, critically revised, and approved the manuscript before submission	have read, critically revised, and approved the manuscript before submission	Wrote the paper	Writing - Review & Editing	YES
5725816	29059709	D.Y.K.	2	were responsible for data acquisition and analysis	were responsible for data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5725816	29059709	F.E.	2	were responsible for conception and design of the study|were responsible for data acquisition and analysis	were responsible for conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5725816	29059709	F.E.	2	were responsible for conception and design of the study|were responsible for data acquisition and analysis	were responsible for data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5725816	29059709	F.L.	2	were responsible for data acquisition and analysis	were responsible for data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5725816	29059709	FE	2	were responsible for drafting the manuscript and figures	were responsible for drafting the manuscript and figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5725816	29059709	FL	2	were responsible for drafting the manuscript and figures	were responsible for drafting the manuscript and figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5725816	29059709	J.K.	2	were responsible for data acquisition and analysis	were responsible for data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5725816	29059709	M.F.	2	were responsible for data acquisition and analysis	were responsible for data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5725816	29059709	N.S.	2	were responsible for data acquisition and analysis	were responsible for data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5725816	29059709	NS	2	were responsible for drafting the manuscript and figures	were responsible for drafting the manuscript and figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5725816	29059709	P.M.	2	were responsible for data acquisition and analysis	were responsible for data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5725816	29059709	R.T.	2	were responsible for data acquisition and analysis	were responsible for data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5725816	29059709	Y.G.	2	were responsible for conception and design of the study|were responsible for data acquisition and analysis	were responsible for conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5725816	29059709	Y.G.	2	were responsible for conception and design of the study|were responsible for data acquisition and analysis	were responsible for data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5725816	29059709	YG	2	were responsible for drafting the manuscript and figures	were responsible for drafting the manuscript and figures	Wrote the paper	Visualization|Writing - Original Draft	YES
1762374	17183661	CC	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762374	17183661	CC	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762374	17183661	MB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1762374	17183661	MS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762374	17183661	MS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762374	17183661	MS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762374	17183661	PA	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762374	17183661	PA	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762374	17183661	XZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4408113	25905459	AP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408113	25905459	AP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408113	25905459	AP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408113	25905459	CG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408113	25905459	CG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408113	25905459	CG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408113	25905459	CG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408113	25905459	GC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408113	25905459	GC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408113	25905459	GC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408113	25905459	GC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408113	25905459	GC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408113	25905459	GF	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408113	25905459	GF	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408113	25905459	JGV	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408113	25905459	MM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408113	25905459	MM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5761719	29249436	All authors	1	Critical revision of the manuscript	Critical revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
3282629	22264389	AT	2	carried out animal handling and analysis of data	carried out animal handling and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3282629	22264389	FUR	2	independently re-analyzed a small subset of data as a quality control check	independently re-analyzed a small subset of data as a quality control check	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Validation	YES
3282629	22264389	K-WJ	2	both revised the manuscript critically for important intellectual content	both revised the manuscript critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
3282629	22264389	MD	2	participated in the analysis and interpretation of data and in revising the manuscript critically	participated in the analysis and interpretation of data and in revising the manuscript critically	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
3282629	22264389	MG	2	participated in the interpretation of data and in the revision of the manuscript critically	participated in the interpretation of data and in the revision of the manuscript critically	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
3282629	22264389	MH	2	contributed in the concept and design of the study as well as in the analysis and interpretation of data, in revising the manuscript critically for important intellectual content, and in the final approval of the manuscript	contributed in the concept and design of the study as well as in the analysis and interpretation of data, in revising the manuscript critically for important intellectual content, and in the final approval of the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Methodology|Resources|Writing - Review & Editing	YES
3282629	22264389	PB	2	both revised the manuscript critically for important intellectual content	both revised the manuscript critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
3282629	22264389	TH	2	contributed in the concept and design of the study as well as in the analysis and interpretation of data	contributed in the concept and design of the study as well as in the analysis and interpretation of data	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Methodology|Resources	YES
5810331	29116684	Alexander Wong	1	Acquisition, analysis or interpretation of data|Critical revision of the manuscript for important intellectual content	Acquisition, analysis or interpretation of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5810331	29116684	Alexander Wong	1	Acquisition, analysis or interpretation of data|Critical revision of the manuscript for important intellectual content	Critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5810331	29116684	Brian Conway	1	Acquisition, analysis or interpretation of data	Acquisition, analysis or interpretation of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5810331	29116684	Curtis Cooper	1	Acquisition, analysis or interpretation of data|Critical revision of the manuscript for important intellectual content	Acquisition, analysis or interpretation of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5810331	29116684	Curtis Cooper	1	Acquisition, analysis or interpretation of data|Critical revision of the manuscript for important intellectual content	Critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5810331	29116684	Erica Moodie	1	Acquisition, analysis or interpretation of data|Critical revision of the manuscript for important intellectual content	Acquisition, analysis or interpretation of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5810331	29116684	Erica Moodie	1	Acquisition, analysis or interpretation of data|Critical revision of the manuscript for important intellectual content	Critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5810331	29116684	Erin Strumpf	1	Acquisition, analysis or interpretation of data|Critical revision of the manuscript for important intellectual content	Acquisition, analysis or interpretation of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5810331	29116684	Erin Strumpf	1	Acquisition, analysis or interpretation of data|Critical revision of the manuscript for important intellectual content	Critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5810331	29116684	Jim Young	1	Acquisition, analysis or interpretation of data|Critical revision of the manuscript for important intellectual content	Acquisition, analysis or interpretation of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5810331	29116684	Jim Young	1	Acquisition, analysis or interpretation of data|Critical revision of the manuscript for important intellectual content	Critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5810331	29116684	Joseph Cox	1	Acquisition, analysis or interpretation of data|Critical revision of the manuscript for important intellectual content	Acquisition, analysis or interpretation of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5810331	29116684	Joseph Cox	1	Acquisition, analysis or interpretation of data|Critical revision of the manuscript for important intellectual content	Critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5810331	29116684	Marie-Lousie Vachon	1	Acquisition, analysis or interpretation of data	Acquisition, analysis or interpretation of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5810331	29116684	Marina Klein	1	Study concept and design|Acquisition, analysis or interpretation of data|Critical revision of the manuscript for important intellectual content|Obtained funding	Study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5810331	29116684	Marina Klein	1	Study concept and design|Acquisition, analysis or interpretation of data|Critical revision of the manuscript for important intellectual content|Obtained funding	Acquisition, analysis or interpretation of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5810331	29116684	Marina Klein	1	Study concept and design|Acquisition, analysis or interpretation of data|Critical revision of the manuscript for important intellectual content|Obtained funding	Critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5810331	29116684	Marina Klein	1	Study concept and design|Acquisition, analysis or interpretation of data|Critical revision of the manuscript for important intellectual content|Obtained funding	Obtained funding	-	Funding acquisition	YES
5810331	29116684	Mark Hull	1	Acquisition, analysis or interpretation of data	Acquisition, analysis or interpretation of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5810331	29116684	Roy Nitulescu	1	Critical revision of the manuscript for important intellectual content	Critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5810331	29116684	Sahar Saeed	1	Study concept and design|Acquisition, analysis or interpretation of data|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content	Study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5810331	29116684	Sahar Saeed	1	Study concept and design|Acquisition, analysis or interpretation of data|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content	Acquisition, analysis or interpretation of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5810331	29116684	Sahar Saeed	1	Study concept and design|Acquisition, analysis or interpretation of data|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content	Drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
5810331	29116684	Sahar Saeed	1	Study concept and design|Acquisition, analysis or interpretation of data|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content	Critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5810331	29116684	Sharon Walmsely	1	Acquisition, analysis or interpretation of data|Critical revision of the manuscript for important intellectual content	Acquisition, analysis or interpretation of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5810331	29116684	Sharon Walmsely	1	Acquisition, analysis or interpretation of data|Critical revision of the manuscript for important intellectual content	Critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5810331	29116684	Valerie Martel-Laferriere	1	Acquisition, analysis or interpretation of data	Acquisition, analysis or interpretation of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4534598	26295043	Hanwei Jiao	2	contributed equally to this work	contributed equally to this work	-	-	NO
4534598	26295043	Li Du	2	contributed equally to this work	contributed equally to this work	-	-	NO
4534598	26295043	Ying Cheng	2	contributed equally to this work	contributed equally to this work	-	-	NO
4408114	25905641	BH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408114	25905641	BH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408114	25905641	BH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408114	25905641	BH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408114	25905641	GK	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408114	25905641	GK	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408114	25905641	JB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408114	25905641	JB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408114	25905641	JB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408114	25905641	PH	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408114	25905641	PH	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408114	25905641	PH	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408114	25905641	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408114	25905641	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408114	25905641	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408114	25905641	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5414186	28464822	KLB	PLoS52	optimized and performed the hmw dna extraction	optimized and performed the hmw dna extraction	Performed the experiments	Investigation	YES
5414186	28464822	MAC	PLoS52	conceived and designed study|performed the genome assembly, evaluation and analyses|wrote the paper	conceived and designed study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5414186	28464822	MAC	PLoS52	conceived and designed study|performed the genome assembly, evaluation and analyses|wrote the paper	performed the genome assembly, evaluation and analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5414186	28464822	MAC	PLoS52	conceived and designed study|performed the genome assembly, evaluation and analyses|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5414186	28464822	TDK	PLoS52	conceived and designed study|wrote the paper	conceived and designed study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5414186	28464822	TDK	PLoS52	conceived and designed study|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5414186	28464822	WJG	PLoS52	organized map data and performed the computational analysis of the sex comparisons	organized map data and performed the computational analysis of the sex comparisons	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
1762375	17183697	AC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762375	17183697	AC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762375	17183697	AC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762375	17183697	AC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3284452	22214308	AS	2	participated in data interpretation and revising the manuscript	participated in data interpretation and revising the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
3284452	22214308	CH	2	participated in the conception and design of the study, data analysis, data interpretation, drafting and revising the manuscript	participated in the conception and design of the study, data analysis, data interpretation, drafting and revising the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
3284452	22214308	LJ	2	participated in data interpretation and revising the manuscript	participated in data interpretation and revising the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
3284452	22214308	MJ	2	participated in the conception and design of the study, data acquisition, data analysis, data interpretation, drafting and revising the manuscript	participated in the conception and design of the study, data acquisition, data analysis, data interpretation, drafting and revising the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
3284452	22214308	OE	2	participated in the conception and design of the study, data acquisition, data analysis, data interpretation, drafting and revising the manuscript	participated in the conception and design of the study, data acquisition, data analysis, data interpretation, drafting and revising the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
3284452	22214308	OK	2	participated in data interpretation and revising the manuscript	participated in data interpretation and revising the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
3284452	22214308	PJ	2	participated in data interpretation and revising the manuscript	participated in data interpretation and revising the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5765487	29023958	C.K.	2	contributed to the conception and design of the study|contributed to drafting the text and preparing the figures	contributed to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5765487	29023958	C.K.	2	contributed to the conception and design of the study|contributed to drafting the text and preparing the figures	contributed to drafting the text and preparing the figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5765487	29023958	E.T.	2	contributed to the acquisition and analysis of data	contributed to the acquisition and analysis of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5765487	29023958	K.S.	2	contributed to the acquisition and analysis of data|contributed to drafting the text and preparing the figures	contributed to the acquisition and analysis of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5765487	29023958	K.S.	2	contributed to the acquisition and analysis of data|contributed to drafting the text and preparing the figures	contributed to drafting the text and preparing the figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5765487	29023958	M.B.	2	contributed to the conception and design of the study|contributed to the acquisition and analysis of data|contributed to drafting the text and preparing the figures	contributed to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5765487	29023958	M.B.	2	contributed to the conception and design of the study|contributed to the acquisition and analysis of data|contributed to drafting the text and preparing the figures	contributed to the acquisition and analysis of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5765487	29023958	M.B.	2	contributed to the conception and design of the study|contributed to the acquisition and analysis of data|contributed to drafting the text and preparing the figures	contributed to drafting the text and preparing the figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5765487	29023958	O.R.	2	contributed to the conception and design of the study|contributed to drafting the text and preparing the figures	contributed to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5765487	29023958	O.R.	2	contributed to the conception and design of the study|contributed to drafting the text and preparing the figures	contributed to drafting the text and preparing the figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5765487	29023958	P.K.	2	contributed to the conception and design of the study|contributed to the acquisition and analysis of data|contributed to drafting the text and preparing the figures	contributed to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5765487	29023958	P.K.	2	contributed to the conception and design of the study|contributed to the acquisition and analysis of data|contributed to drafting the text and preparing the figures	contributed to the acquisition and analysis of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5765487	29023958	P.K.	2	contributed to the conception and design of the study|contributed to the acquisition and analysis of data|contributed to drafting the text and preparing the figures	contributed to drafting the text and preparing the figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5765487	29023958	P.U.H.	2	contributed to the conception and design of the study|contributed to drafting the text and preparing the figures	contributed to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5765487	29023958	P.U.H.	2	contributed to the conception and design of the study|contributed to drafting the text and preparing the figures	contributed to drafting the text and preparing the figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5765487	29023958	R.A.W.	2	contributed to the acquisition and analysis of data|contributed to drafting the text and preparing the figures	contributed to the acquisition and analysis of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5765487	29023958	R.A.W.	2	contributed to the acquisition and analysis of data|contributed to drafting the text and preparing the figures	contributed to drafting the text and preparing the figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5765487	29023958	S.F.	2	contributed to the conception and design of the study|contributed to drafting the text and preparing the figures	contributed to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5765487	29023958	S.F.	2	contributed to the conception and design of the study|contributed to drafting the text and preparing the figures	contributed to drafting the text and preparing the figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5765487	29023958	T.H.	2	contributed to the acquisition and analysis of data|contributed to drafting the text and preparing the figures	contributed to the acquisition and analysis of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5765487	29023958	T.H.	2	contributed to the acquisition and analysis of data|contributed to drafting the text and preparing the figures	contributed to drafting the text and preparing the figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5765487	29023958	U.H.	2	contributed to the conception and design of the study|contributed to drafting the text and preparing the figures	contributed to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5765487	29023958	U.H.	2	contributed to the conception and design of the study|contributed to drafting the text and preparing the figures	contributed to drafting the text and preparing the figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5611435	28979287	EN	PLoS52	performed the dual luc assays	performed the dual luc assays	Performed the experiments	Investigation	YES
5611435	28979287	GS	PLoS52	performed the dual luc assays	performed the dual luc assays	Performed the experiments	Investigation	YES
5611435	28979287	JD-M	PLoS52	performed computational analysis to predict mir529b target sequences	performed computational analysis to predict mir529b target sequences	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5611435	28979287	L-SP	PLoS52	performed the dual luc assays	performed the dual luc assays	Performed the experiments	Investigation	YES
5611435	28979287	LC	PLoS52	cloned the constructs|performed the dual luc assays|analyzed the data	cloned the constructs	Performed the experiments	Investigation	YES
5611435	28979287	LC	PLoS52	cloned the constructs|performed the dual luc assays|analyzed the data	performed the dual luc assays	Performed the experiments	Investigation	YES
5611435	28979287	LC	PLoS52	cloned the constructs|performed the dual luc assays|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5611435	28979287	PS	PLoS52	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5611435	28979287	RM	PLoS52	designed the experiments|cloned the constructs|performed the dual luc assays|analyzed the data|drafted the manuscript and all authors edited and approved the final version	designed the experiments	Conceived and designed the experiments	Methodology	YES
5611435	28979287	RM	PLoS52	designed the experiments|cloned the constructs|performed the dual luc assays|analyzed the data|drafted the manuscript and all authors edited and approved the final version	cloned the constructs	Performed the experiments	Investigation	YES
5611435	28979287	RM	PLoS52	designed the experiments|cloned the constructs|performed the dual luc assays|analyzed the data|drafted the manuscript and all authors edited and approved the final version	performed the dual luc assays	Performed the experiments	Investigation	YES
5611435	28979287	RM	PLoS52	designed the experiments|cloned the constructs|performed the dual luc assays|analyzed the data|drafted the manuscript and all authors edited and approved the final version	analyzed the data	Analyzed the data	Formal analysis	YES
5611435	28979287	RM	PLoS52	designed the experiments|cloned the constructs|performed the dual luc assays|analyzed the data|drafted the manuscript and all authors edited and approved the final version	drafted the manuscript and all authors edited and approved the final version	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4408115	25906065	CAB	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408115	25906065	CAB	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408115	25906065	DM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408115	25906065	DM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408115	25906065	DM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408115	25906065	DM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408115	25906065	EJS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408115	25906065	EJS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408115	25906065	EJS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408115	25906065	EJS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408115	25906065	GNP	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408115	25906065	GNP	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408115	25906065	HC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408115	25906065	HC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408115	25906065	HC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408115	25906065	LPF	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408115	25906065	LPF	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408115	25906065	LPF	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408115	25906065	MEA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408115	25906065	MEA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408115	25906065	MEA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408115	25906065	MEA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408115	25906065	RY	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408115	25906065	RY	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408115	25906065	RY	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408115	25906065	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408115	25906065	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408115	25906065	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408115	25906065	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3285530	22214394	AAL	2	reviewed the manuscript, contributed to the intellectual content, and approved the final content of the manuscript	reviewed the manuscript, contributed to the intellectual content, and approved the final content of the manuscript	Wrote the paper	Writing - Review & Editing	YES
3285530	22214394	All authors	2	reviewed the collected data and interpretation, provided feedback for further research during the study, and approved the final submitted version of this manuscript	reviewed the collected data and interpretation, provided feedback for further research during the study, and approved the final submitted version of this manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
3285530	22214394	CJH	2	performed part of the data acquisition and critically reviewed the manuscript	performed part of the data acquisition and critically reviewed the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
3285530	22214394	FHPvV	2	performed the data interpretation, implemented some of the tumor delineation methods, and assisted in drafting the manuscript	performed the data interpretation, implemented some of the tumor delineation methods, and assisted in drafting the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3285530	22214394	LMV	2	provided the pet image data and reviewed the manuscript	provided the pet image data and reviewed the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Visualization|Writing - Review & Editing	YES
3285530	22214394	MY	2	implemented some of the tools to perform tumor delineations and critically reviewed the manuscript	implemented some of the tools to perform tumor delineations and critically reviewed the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
3285530	22214394	OSH	2	reviewed the manuscript and approved its final content	reviewed the manuscript and approved its final content	Wrote the paper	Writing - Review & Editing	YES
3285530	22214394	PC	2	performed the data analysis and data interpretation and was the main author of the manuscript	performed the data analysis and data interpretation and was the main author of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3285530	22214394	RB	2	performed the study design, implemented some of the tumor delineation methods, supervised the project, and reviewed and approved the final content of the manuscript	performed the study design, implemented some of the tumor delineation methods, supervised the project, and reviewed and approved the final content of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Supervision|Writing - Review & Editing	YES
5810333	29314658	All authors	2	analysed the data, contributed to the writing of the manuscript, read and met the criteria for authorship and agreed with manuscript results and conclusions	analysed the data, contributed to the writing of the manuscript, read and met the criteria for authorship and agreed with manuscript results and conclusions	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5810333	29314658	Delphine Perriat	2	conceived and designed the study|organized and conducted the data collection|wrote the first draft of the manuscript and also produced the figures and the tables	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5810333	29314658	Delphine Perriat	2	conceived and designed the study|organized and conducted the data collection|wrote the first draft of the manuscript and also produced the figures and the tables	organized and conducted the data collection	Performed the experiments	Investigation	YES
5810333	29314658	Delphine Perriat	2	conceived and designed the study|organized and conducted the data collection|wrote the first draft of the manuscript and also produced the figures and the tables	wrote the first draft of the manuscript and also produced the figures and the tables	Wrote the paper	Visualization|Writing - Original Draft	YES
5810333	29314658	Fiona Walsh	2	organized and conducted the data collection	organized and conducted the data collection	Performed the experiments	Investigation	YES
5810333	29314658	Francois Dabis	2	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5810333	29314658	Joanna Orne-Gliemann	2	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5810333	29314658	Kalpana Sabapathy	2	organized and conducted the data collection	organized and conducted the data collection	Performed the experiments	Investigation	YES
5810333	29314658	Laura Balzer	2	organized and conducted the data collection	organized and conducted the data collection	Performed the experiments	Investigation	YES
5810333	29314658	Shahin Lockman	2	organized and conducted the data collection	organized and conducted the data collection	Performed the experiments	Investigation	YES
1762376	17183731	HS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762376	17183731	HS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762376	17183731	HS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762376	17183731	HS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762376	17183731	JY	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762376	17183731	JY	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762376	17183731	JY	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5414199	28464849	BJS	2	conceived of and coordinated the project and edited the manuscript	conceived of and coordinated the project and edited the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Project administration|Writing - Review & Editing	YES
5414199	28464849	KMG	2	conducted rt pcrs	conducted rt pcrs	Performed the experiments	Investigation	YES
5414199	28464849	MED	2	contributed to the conception of the study, collected and isolated rna samples, performed rna seq data analysis, and drafted portions of the manuscript	contributed to the conception of the study, collected and isolated rna samples, performed rna seq data analysis, and drafted portions of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Resources|Writing - Original Draft	YES
5766825	29208425	All authors	2	revised it critically for important intellectual content and approved the final version of the manuscript	revised it critically for important intellectual content and approved the final version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5766825	29208425	LL	2	contributed to the acquisition of the data	contributed to the acquisition of the data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5766825	29208425	OP	2	contributed to the analysis of the paper	contributed to the analysis of the paper	-	-	NO
5766825	29208425	PHW	2	contributed to the interpretation of the data|contributed to the acquisition of the data	contributed to the interpretation of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5766825	29208425	PHW	2	contributed to the interpretation of the data|contributed to the acquisition of the data	contributed to the acquisition of the data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5766825	29208425	SGW	2	initiated the concept and design of the paper, analysed the data and drafted the manuscript|is the guarantor for the manuscript and has full access to all the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis	initiated the concept and design of the paper, analysed the data and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
5766825	29208425	SGW	2	initiated the concept and design of the paper, analysed the data and drafted the manuscript|is the guarantor for the manuscript and has full access to all the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis	is the guarantor for the manuscript and has full access to all the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis	Analyzed the data	Data curation|Formal analysis	YES
5838522	29331092	A.E.	2	contributed to the conception and design of the study|contributed to the acquisition and analysis of data|contributed to drafting the text and preparing the figures	contributed to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5838522	29331092	A.E.	2	contributed to the conception and design of the study|contributed to the acquisition and analysis of data|contributed to drafting the text and preparing the figures	contributed to the acquisition and analysis of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5838522	29331092	A.E.	2	contributed to the conception and design of the study|contributed to the acquisition and analysis of data|contributed to drafting the text and preparing the figures	contributed to drafting the text and preparing the figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5838522	29331092	A.J.T.	2	contributed to the conception and design of the study	contributed to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5838522	29331092	A.R.	2	contributed to the acquisition and analysis of data	contributed to the acquisition and analysis of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5838522	29331092	C.A.M.G.W.-K.	2	contributed to the conception and design of the study|contributed to the acquisition and analysis of data	contributed to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5838522	29331092	C.A.M.G.W.-K.	2	contributed to the conception and design of the study|contributed to the acquisition and analysis of data	contributed to the acquisition and analysis of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5838522	29331092	C.E.	2	contributed to the acquisition and analysis of data|contributed to the acquisition and analysis of data	contributed to the acquisition and analysis of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5838522	29331092	C.E.	2	contributed to the acquisition and analysis of data|contributed to the acquisition and analysis of data	contributed to the acquisition and analysis of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5838522	29331092	C.E.L.	2	contributed to the acquisition and analysis of data	contributed to the acquisition and analysis of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5838522	29331092	C.G.	2	contributed to the acquisition and analysis of data	contributed to the acquisition and analysis of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5838522	29331092	C.T.	2	contributed to the conception and design of the study|contributed to the acquisition and analysis of data	contributed to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5838522	29331092	C.T.	2	contributed to the conception and design of the study|contributed to the acquisition and analysis of data	contributed to the acquisition and analysis of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5838522	29331092	D.C.	2	contributed to the conception and design of the study|contributed to the acquisition and analysis of data	contributed to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5838522	29331092	D.C.	2	contributed to the conception and design of the study|contributed to the acquisition and analysis of data	contributed to the acquisition and analysis of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5838522	29331092	D.C.A.	2	contributed to the conception and design of the study	contributed to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5838522	29331092	D.R.A.	2	contributed to the conception and design of the study	contributed to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5838522	29331092	F.B.	2	contributed to the conception and design of the study	contributed to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5838522	29331092	F.D.A.	2	contributed to the acquisition and analysis of data	contributed to the acquisition and analysis of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5838522	29331092	F.P.	2	contributed to the conception and design of the study|contributed to the acquisition and analysis of data	contributed to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5838522	29331092	F.P.	2	contributed to the conception and design of the study|contributed to the acquisition and analysis of data	contributed to the acquisition and analysis of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5838522	29331092	H.V.	2	contributed to the acquisition and analysis of data	contributed to the acquisition and analysis of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5838522	29331092	J.K.	2	contributed to the acquisition and analysis of data	contributed to the acquisition and analysis of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5838522	29331092	J.S.G.	2	contributed to the acquisition and analysis of data	contributed to the acquisition and analysis of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5838522	29331092	L.P.	2	contributed to the acquisition and analysis of data	contributed to the acquisition and analysis of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5838522	29331092	M.A.R.	2	contributed to the acquisition and analysis of data	contributed to the acquisition and analysis of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5838522	29331092	M.B.	2	contributed to the acquisition and analysis of data	contributed to the acquisition and analysis of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5838522	29331092	M.F.	2	contributed to the acquisition and analysis of data	contributed to the acquisition and analysis of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5838522	29331092	M.J.C.	2	contributed to the conception and design of the study	contributed to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5838522	29331092	M.L.S.	2	contributed to the acquisition and analysis of data	contributed to the acquisition and analysis of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5838522	29331092	N.C.	2	contributed to the acquisition and analysis of data	contributed to the acquisition and analysis of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5838522	29331092	N.D.S.	2	contributed to the acquisition and analysis of data	contributed to the acquisition and analysis of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5838522	29331092	O.C.	2	contributed to the conception and design of the study|contributed to the acquisition and analysis of data|contributed to drafting the text and preparing the figures	contributed to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5838522	29331092	O.C.	2	contributed to the conception and design of the study|contributed to the acquisition and analysis of data|contributed to drafting the text and preparing the figures	contributed to the acquisition and analysis of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5838522	29331092	O.C.	2	contributed to the conception and design of the study|contributed to the acquisition and analysis of data|contributed to drafting the text and preparing the figures	contributed to drafting the text and preparing the figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5838522	29331092	S.H.P.	2	contributed to the acquisition and analysis of data	contributed to the acquisition and analysis of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5838522	29331092	S.O.	2	contributed to the acquisition and analysis of data	contributed to the acquisition and analysis of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5838522	29331092	S.R.	2	contributed to the acquisition and analysis of data	contributed to the acquisition and analysis of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5838522	29331092	W.B.	2	contributed to the acquisition and analysis of data	contributed to the acquisition and analysis of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5611443	28979286	AB	7	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5611443	28979286	FM	7	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5611443	28979286	JP	7	designed experiments|performed the experiments|analyzed data|wrote the paper	designed experiments	Conceived and designed the experiments	Methodology	YES
5611443	28979286	JP	7	designed experiments|performed the experiments|analyzed data|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5611443	28979286	JP	7	designed experiments|performed the experiments|analyzed data|wrote the paper	analyzed data	Analyzed the data	Formal analysis	YES
5611443	28979286	JP	7	designed experiments|performed the experiments|analyzed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5611443	28979286	RC	7	designed experiments|analyzed data|wrote the paper	designed experiments	Conceived and designed the experiments	Methodology	YES
5611443	28979286	RC	7	designed experiments|analyzed data|wrote the paper	analyzed data	Analyzed the data	Formal analysis	YES
5611443	28979286	RC	7	designed experiments|analyzed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3292467	22214362	ADS	2	did the design of the study and revised the whole manuscript	did the design of the study and revised the whole manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
3292467	22214362	BW	2	carried out the synthesis of tracers	carried out the synthesis of tracers	Performed the experiments	Investigation	YES
3292467	22214362	CC	2	participated in the whole study and wrote the manuscript	participated in the whole study and wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3292467	22214362	CW	2	carried out the synthesis of tracers	carried out the synthesis of tracers	Performed the experiments	Investigation	YES
3292467	22214362	LGS	2	did the design of the study and revised the whole manuscript	did the design of the study and revised the whole manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
3292467	22214362	LP	2	performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
3292467	22214362	MS	2	carried out the synthesis of tracers	carried out the synthesis of tracers	Performed the experiments	Investigation	YES
3292467	22214362	UH	2	gave financial support	gave financial support	-	Funding acquisition	YES
1762377	17183642	HT	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762377	17183642	HW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762377	17183642	HW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762377	17183642	HW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762377	17183642	HW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762377	17183642	JZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1762377	17183642	QC	PLoS5	Performed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1762377	17183642	QC	PLoS5	Performed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1762377	17183642	SL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1762377	17183642	XC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1762377	17183642	YZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762377	17183642	YZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762377	17183642	YZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762377	17183642	YZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762377	17183642	ZX	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762377	17183642	ZX	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5810336	29165892	CM	2	designed the study|collected and analyzed the data|wrote the initial draft of the manuscript, and all authors reviewed and provided substantive comments on the draft	designed the study	Conceived and designed the experiments	Methodology	YES
5810336	29165892	CM	2	designed the study|collected and analyzed the data|wrote the initial draft of the manuscript, and all authors reviewed and provided substantive comments on the draft	collected and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5810336	29165892	CM	2	designed the study|collected and analyzed the data|wrote the initial draft of the manuscript, and all authors reviewed and provided substantive comments on the draft	wrote the initial draft of the manuscript, and all authors reviewed and provided substantive comments on the draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5810336	29165892	JO	2	reviewed and provided substantive comments on the study design	reviewed and provided substantive comments on the study design	Conceived and designed the experiments	Methodology	YES
5810336	29165892	JT	2	collected and analyzed the data	collected and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5810336	29165892	MA	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5810336	29165892	NM	2	collected and analyzed the data|wrote the initial draft of the manuscript, and all authors reviewed and provided substantive comments on the draft	collected and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5810336	29165892	NM	2	collected and analyzed the data|wrote the initial draft of the manuscript, and all authors reviewed and provided substantive comments on the draft	wrote the initial draft of the manuscript, and all authors reviewed and provided substantive comments on the draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5810336	29165892	NP	2	reviewed and provided substantive comments on the study design	reviewed and provided substantive comments on the study design	Conceived and designed the experiments	Methodology	YES
5810336	29165892	PD	2	reviewed and provided substantive comments on the study design	reviewed and provided substantive comments on the study design	Conceived and designed the experiments	Methodology	YES
5810336	29165892	PS	2	collected and analyzed the data	collected and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5810336	29165892	RH	2	designed the study|collected and analyzed the data|wrote the initial draft of the manuscript, and all authors reviewed and provided substantive comments on the draft	designed the study	Conceived and designed the experiments	Methodology	YES
5810336	29165892	RH	2	designed the study|collected and analyzed the data|wrote the initial draft of the manuscript, and all authors reviewed and provided substantive comments on the draft	collected and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5810336	29165892	RH	2	designed the study|collected and analyzed the data|wrote the initial draft of the manuscript, and all authors reviewed and provided substantive comments on the draft	wrote the initial draft of the manuscript, and all authors reviewed and provided substantive comments on the draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5810336	29165892	SO	2	reviewed and provided substantive comments on the study design	reviewed and provided substantive comments on the study design	Conceived and designed the experiments	Methodology	YES
5810336	29165892	TM	2	reviewed and provided substantive comments on the study design	reviewed and provided substantive comments on the study design	Conceived and designed the experiments	Methodology	YES
4408116	25905463	HYY	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4408116	25905463	HYY	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4408116	25905463	JC	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408116	25905463	JC	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408116	25905463	JL	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4408116	25905463	SNY	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408116	25905463	XLJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408116	25905463	XLJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408116	25905463	XLJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408116	25905463	XLJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408116	25905463	XYC	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4408116	25905463	YS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408116	25905463	YS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4408116	25905463	YS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4408116	25905463	ZHL	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
3292493	22284727	LJ	2	participated in the study design and coordination|proofread the manuscript	participated in the study design and coordination	Conceived and designed the experiments	Methodology|Project administration	YES
3292493	22284727	LJ	2	participated in the study design and coordination|proofread the manuscript	proofread the manuscript	-	-	NO
3292493	22284727	MB	2	participated in the study design and coordination|drafted the manuscript	participated in the study design and coordination	Conceived and designed the experiments	Methodology|Project administration	YES
3292493	22284727	MB	2	participated in the study design and coordination|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
3292493	22284727	MG	2	participated in the study design and coordination|proofread the manuscript	participated in the study design and coordination	Conceived and designed the experiments	Methodology|Project administration	YES
3292493	22284727	MG	2	participated in the study design and coordination|proofread the manuscript	proofread the manuscript	-	-	NO
3292493	22284727	OCB	2	participated in the study design and coordination|proofread the manuscript	participated in the study design and coordination	Conceived and designed the experiments	Methodology|Project administration	YES
3292493	22284727	OCB	2	participated in the study design and coordination|proofread the manuscript	proofread the manuscript	-	-	NO
3292493	22284727	WJGO	2	proofread the manuscript	proofread the manuscript	-	-	NO
5611485	28979272	All authors	PLoS52	supervised and complemented the writing|agree to be accountable for the content of the work	supervised and complemented the writing	Wrote the paper	Supervision	YES
5611485	28979272	All authors	PLoS52	supervised and complemented the writing|agree to be accountable for the content of the work	agree to be accountable for the content of the work	-	-	NO
5611485	28979272	CL	PLoS52	supervised the experiments	supervised the experiments	-	Supervision	YES
5611485	28979272	DL	PLoS52	conceived the original project and research plans|supervised the experiments	conceived the original project and research plans	Conceived and designed the experiments	Conceptualization	YES
5611485	28979272	DL	PLoS52	conceived the original project and research plans|supervised the experiments	supervised the experiments	-	Supervision	YES
5611485	28979272	HZ	PLoS52	provided technical assistance	provided technical assistance	Performed the experiments	Investigation	YES
5611485	28979272	LC	PLoS52	conceived the original project and research plans|supervised the experiments	conceived the original project and research plans	Conceived and designed the experiments	Conceptualization	YES
5611485	28979272	LC	PLoS52	conceived the original project and research plans|supervised the experiments	supervised the experiments	-	Supervision	YES
5611485	28979272	QZ	PLoS52	designed the experiments and performed most of the experiments|analyzed the data|wrote the article with contributions of all the authors	designed the experiments and performed most of the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5611485	28979272	QZ	PLoS52	designed the experiments and performed most of the experiments|analyzed the data|wrote the article with contributions of all the authors	analyzed the data	Analyzed the data	Formal analysis	YES
5611485	28979272	QZ	PLoS52	designed the experiments and performed most of the experiments|analyzed the data|wrote the article with contributions of all the authors	wrote the article with contributions of all the authors	Wrote the paper	Writing - Original Draft	YES
5611485	28979272	SN	PLoS52	analyzed the data|provided technical assistance|wrote the article with contributions of all the authors	analyzed the data	Analyzed the data	Formal analysis	YES
5611485	28979272	SN	PLoS52	analyzed the data|provided technical assistance|wrote the article with contributions of all the authors	provided technical assistance	Performed the experiments	Investigation	YES
5611485	28979272	SN	PLoS52	analyzed the data|provided technical assistance|wrote the article with contributions of all the authors	wrote the article with contributions of all the authors	Wrote the paper	Writing - Original Draft	YES
5611485	28979272	WD	PLoS52	provided technical assistance	provided technical assistance	Performed the experiments	Investigation	YES
5611485	28979272	XG	PLoS52	provided technical assistance	provided technical assistance	Performed the experiments	Investigation	YES
5611485	28979272	XZ	PLoS52	designed the experiments and performed most of the experiments|analyzed the data	designed the experiments and performed most of the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5611485	28979272	XZ	PLoS52	designed the experiments and performed most of the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
1762378	17183678	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762378	17183678	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762378	17183678	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762378	17183678	IU	PLoS5	Overviewed the manuscript	Overviewed the manuscript	-	-	NO
1762378	17183678	KK	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762378	17183678	TY	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762378	17183678	TY	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762378	17183678	TY	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5415748	28468647	BLT	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5415748	28468647	HJF	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5415748	28468647	KYZ	PLoS52	analyzed and interpreted the data	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5415748	28468647	SX	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5415748	28468647	TL	PLoS52	analyzed and interpreted the data|wrote the manuscript	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5415748	28468647	TL	PLoS52	analyzed and interpreted the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5415748	28468647	WJL	PLoS52	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5415748	28468647	ZW	PLoS52	analyzed and interpreted the data	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
3298693	22284761	C-HC	2	synthesized and purified the pretargeting agents	synthesized and purified the pretargeting agents	Performed the experiments	Investigation	YES
3298693	22284761	DMG	2	participated in the design of the study and helped draft the manuscript	participated in the design of the study and helped draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3298693	22284761	GMF	2	carried out the labeling procedures and the imaging studies	carried out the labeling procedures and the imaging studies	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
3298693	22284761	OCB	2	conceived the study, participated in the design of the study, and helped draft the manuscript	conceived the study, participated in the design of the study, and helped draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
3298693	22284761	PL	2	carried out the imaging studies and helped with the analysis of the studies	carried out the imaging studies and helped with the analysis of the studies	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
3298693	22284761	RMS	2	participated in the design of the study and helped draft the manuscript	participated in the design of the study and helped draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3298693	22284761	RS	2	conceived the study, carried out the imaging studies and the analysis of the studies, and drafted the manuscript	conceived the study, carried out the imaging studies and the analysis of the studies, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Investigation|Visualization|Writing - Original Draft	YES
3298693	22284761	WJGO	2	carried out the analysis of the imaging studies and helped draft the manuscript	carried out the analysis of the imaging studies and helped draft the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Investigation|Visualization|Writing - Original Draft	YES
3298693	22284761	WJM	2	synthesized and purified the pretargeting agents	synthesized and purified the pretargeting agents	Performed the experiments	Investigation	YES
3298693	22284761	WTAG	2	conceived the study and helped draft the manuscript	conceived the study and helped draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5810338	29381257	AES	2	contributed to the analysis and interpretation of data	contributed to the analysis and interpretation of data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5810338	29381257	All authors	2	have been involved in drafting the manuscript or revising it critically for intellectual content and have given approval for the final version to be published	have been involved in drafting the manuscript or revising it critically for intellectual content and have given approval for the final version to be published	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5810338	29381257	AvH	2	contributed to the concept and design, data acquisition, and interpretation	contributed to the concept and design, data acquisition, and interpretation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
5810338	29381257	CC	2	contributed to the study conception, acquisition and interpretation of data	contributed to the study conception, acquisition and interpretation of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
5810338	29381257	ET	2	contributed to the concept and design and data acquisition	contributed to the concept and design and data acquisition	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceptualization|Investigation|Resources	YES
5810338	29381257	HvR	2	contributed to the concept and design, data acquisition, and interpretation	contributed to the concept and design, data acquisition, and interpretation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
5810338	29381257	JMB	2	contributed to the study conception and interpretation of data	contributed to the study conception and interpretation of data	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Resources	YES
5810338	29381257	JPH	2	contributed to the study design, analysis, and interpretation	contributed to the study design, analysis, and interpretation	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5810338	29381257	RVB	2	contributed to the study conception, data acquisition and interpretation	contributed to the study conception, data acquisition and interpretation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
5810338	29381257	TTS	2	contributed to the data analysis and interpretation	contributed to the data analysis and interpretation	Analyzed the data	Formal analysis	YES
5900999	29466841	E.B.	2	contributed to the conception and design of the study|contributed to the acquisition and analysis of data|contributed to drafting the text and preparing the figures	contributed to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5900999	29466841	E.B.	2	contributed to the conception and design of the study|contributed to the acquisition and analysis of data|contributed to drafting the text and preparing the figures	contributed to the acquisition and analysis of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5900999	29466841	E.B.	2	contributed to the conception and design of the study|contributed to the acquisition and analysis of data|contributed to drafting the text and preparing the figures	contributed to drafting the text and preparing the figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5900999	29466841	E.M.C.H.	2	contributed to the acquisition and analysis of data|contributed to drafting the text and preparing the figures	contributed to the acquisition and analysis of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5900999	29466841	E.M.C.H.	2	contributed to the acquisition and analysis of data|contributed to drafting the text and preparing the figures	contributed to drafting the text and preparing the figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5900999	29466841	H.D.M.	2	contributed to the conception and design of the study|contributed to the acquisition and analysis of data	contributed to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5900999	29466841	H.D.M.	2	contributed to the conception and design of the study|contributed to the acquisition and analysis of data	contributed to the acquisition and analysis of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5900999	29466841	H.K.	2	contributed to the acquisition and analysis of data	contributed to the acquisition and analysis of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5900999	29466841	M.B.	2	contributed to the acquisition and analysis of data	contributed to the acquisition and analysis of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5900999	29466841	M.D.	2	contributed to the conception and design of the study|contributed to the acquisition and analysis of data|contributed to drafting the text and preparing the figures	contributed to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5900999	29466841	M.D.	2	contributed to the conception and design of the study|contributed to the acquisition and analysis of data|contributed to drafting the text and preparing the figures	contributed to the acquisition and analysis of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5900999	29466841	M.D.	2	contributed to the conception and design of the study|contributed to the acquisition and analysis of data|contributed to drafting the text and preparing the figures	contributed to drafting the text and preparing the figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5900999	29466841	M.H.P.K.	2	contributed to the acquisition and analysis of data	contributed to the acquisition and analysis of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5900999	29466841	M.S.v.d.K.	2	contributed to the conception and design of the study|contributed to the acquisition and analysis of data|contributed to drafting the text and preparing the figures	contributed to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5900999	29466841	M.S.v.d.K.	2	contributed to the conception and design of the study|contributed to the acquisition and analysis of data|contributed to drafting the text and preparing the figures	contributed to the acquisition and analysis of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5900999	29466841	M.S.v.d.K.	2	contributed to the conception and design of the study|contributed to the acquisition and analysis of data|contributed to drafting the text and preparing the figures	contributed to drafting the text and preparing the figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5900999	29466841	O.S.	2	contributed to the acquisition and analysis of data	contributed to the acquisition and analysis of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5900999	29466841	R.C.W.	2	contributed to the acquisition and analysis of data	contributed to the acquisition and analysis of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5900999	29466841	R.M.	2	contributed to the conception and design of the study|contributed to the acquisition and analysis of data|contributed to drafting the text and preparing the figures	contributed to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5900999	29466841	R.M.	2	contributed to the conception and design of the study|contributed to the acquisition and analysis of data|contributed to drafting the text and preparing the figures	contributed to the acquisition and analysis of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5900999	29466841	R.M.	2	contributed to the conception and design of the study|contributed to the acquisition and analysis of data|contributed to drafting the text and preparing the figures	contributed to drafting the text and preparing the figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5900999	29466841	U.B.	2	contributed to the acquisition and analysis of data	contributed to the acquisition and analysis of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
4408119	25905458	CHP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4408119	25905458	PFL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4408119	25905458	WDY	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4408119	25905458	WHX	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4408119	25905458	WHX	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408119	25905458	XLZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4408119	25905458	XWD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408119	25905458	XWD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408119	25905458	XWD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408119	25905458	XWD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408119	25905458	XWD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408119	25905458	YQL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408119	25905458	YQL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408119	25905458	YQL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408119	25905458	YQL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408119	25905458	YQL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408119	25905458	ZHH	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4408119	25905458	ZHH	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5611487	28979275	BC	2	performed experiments and analyzed data	performed experiments and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5611487	28979275	BH	2	performed experiments and analyzed data	performed experiments and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5611487	28979275	GZ	2	performed experiments and analyzed data|conducted bioinformatics analyses	performed experiments and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5611487	28979275	GZ	2	performed experiments and analyzed data|conducted bioinformatics analyses	conducted bioinformatics analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5611487	28979275	JY	2	performed experiments and analyzed data	performed experiments and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5611487	28979275	JZ	2	planned and designed the research|wrote the manuscript	planned and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5611487	28979275	JZ	2	planned and designed the research|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5611487	28979275	MA	2	performed experiments and analyzed data	performed experiments and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5611487	28979275	SM	2	performed experiments and analyzed data|conducted bioinformatics analyses|wrote the manuscript	performed experiments and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5611487	28979275	SM	2	performed experiments and analyzed data|conducted bioinformatics analyses|wrote the manuscript	conducted bioinformatics analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5611487	28979275	SM	2	performed experiments and analyzed data|conducted bioinformatics analyses|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3298710	22348532	AW	2	carried out the dna damage studies	carried out the dna damage studies	Performed the experiments	Investigation	YES
3298710	22348532	BC	2	conceived the study and participated in its design and coordination|designed and carried out in vivo experiments	conceived the study and participated in its design and coordination	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
3298710	22348532	BC	2	conceived the study and participated in its design and coordination|designed and carried out in vivo experiments	designed and carried out in vivo experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3298710	22348532	CW	2	performed immunocytochemistry	performed immunocytochemistry	Performed the experiments	Investigation	YES
3298710	22348532	KV	2	conceived the study and participated in its design and coordination	conceived the study and participated in its design and coordination	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
3298710	22348532	SS	2	designed and carried out in vivo experiments	designed and carried out in vivo experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3298710	22348532	VK	2	designed and carried out in vivo experiments	designed and carried out in vivo experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5415952	28472926	DL	2	interpreted the data and wrote the manuscript	interpreted the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5415952	28472926	EV	2	isolated and cultured or supplied isolates	isolated and cultured or supplied isolates	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5415952	28472926	HMBSS	2	performed data analyses|interpreted the data and wrote the manuscript	performed data analyses	Analyzed the data	Formal analysis	YES
5415952	28472926	HMBSS	2	performed data analyses|interpreted the data and wrote the manuscript	interpreted the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5415952	28472926	KDA	2	isolated and cultured or supplied isolates	isolated and cultured or supplied isolates	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5415952	28472926	KL	2	isolated and cultured or supplied isolates	isolated and cultured or supplied isolates	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5415952	28472926	KS	2	isolated and cultured or supplied isolates	isolated and cultured or supplied isolates	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5415952	28472926	LSB	2	performed data analyses|contributed to the manuscript	performed data analyses	Analyzed the data	Formal analysis	YES
5415952	28472926	LSB	2	performed data analyses|contributed to the manuscript	contributed to the manuscript	-	-	NO
5415952	28472926	ML	2	isolated and cultured or supplied isolates|contributed to the manuscript	isolated and cultured or supplied isolates	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5415952	28472926	ML	2	isolated and cultured or supplied isolates|contributed to the manuscript	contributed to the manuscript	-	-	NO
5415952	28472926	MS	2	isolated and cultured or supplied isolates	isolated and cultured or supplied isolates	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5415952	28472926	NRT	2	interpreted the data and wrote the manuscript	interpreted the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5415952	28472926	SRH	2	performed data analyses|contributed to the manuscript	performed data analyses	Analyzed the data	Formal analysis	YES
5415952	28472926	SRH	2	performed data analyses|contributed to the manuscript	contributed to the manuscript	-	-	NO
5415952	28472926	VIS	2	isolated and cultured or supplied isolates	isolated and cultured or supplied isolates	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5810339	29052344	A.K.	2	provided technical oversight	provided technical oversight	-	Supervision	YES
5810339	29052344	All authors	2	contributed to the conception and design of the study|participated in writing the manuscript and approved the final version	contributed to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5810339	29052344	All authors	2	contributed to the conception and design of the study|participated in writing the manuscript and approved the final version	participated in writing the manuscript and approved the final version	Wrote the paper	Writing - Original Draft	YES
5810339	29052344	E.R.	2	conducted the study|did the data analysis|developed the first draft	conducted the study	Performed the experiments	Investigation	YES
5810339	29052344	E.R.	2	conducted the study|did the data analysis|developed the first draft	did the data analysis	Analyzed the data	Formal analysis	YES
5810339	29052344	E.R.	2	conducted the study|did the data analysis|developed the first draft	developed the first draft	Wrote the paper	Writing - Original Draft	YES
5810339	29052344	H.G.	2	developed the first draft	developed the first draft	Wrote the paper	Writing - Original Draft	YES
5810339	29052344	K.B.	2	did the data analysis|developed the first draft	did the data analysis	Analyzed the data	Formal analysis	YES
5810339	29052344	K.B.	2	did the data analysis|developed the first draft	developed the first draft	Wrote the paper	Writing - Original Draft	YES
5901021	29461643	A.S.V.	2	participated in the study concept and design|contributed to drafting the manuscript and the figures	participated in the study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5901021	29461643	A.S.V.	2	participated in the study concept and design|contributed to drafting the manuscript and the figures	contributed to drafting the manuscript and the figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5901021	29461643	All authors	2	performed data acquisition and analysis	performed data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5901021	29461643	D.B.D.	2	participated in the study concept and design	participated in the study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5901021	29461643	F.C.	2	contributed to drafting the manuscript and the figures	contributed to drafting the manuscript and the figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5901021	29461643	F.R.	2	contributed to drafting the manuscript and the figures	contributed to drafting the manuscript and the figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5901021	29461643	F.R.T.	2	participated in the study concept and design|contributed to drafting the manuscript and the figures	participated in the study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5901021	29461643	F.R.T.	2	participated in the study concept and design|contributed to drafting the manuscript and the figures	contributed to drafting the manuscript and the figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5901021	29461643	I.L.-C.	2	participated in the study concept and design|contributed to drafting the manuscript and the figures	participated in the study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5901021	29461643	I.L.-C.	2	participated in the study concept and design|contributed to drafting the manuscript and the figures	contributed to drafting the manuscript and the figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5901021	29461643	R.S.	2	participated in the study concept and design|contributed to drafting the manuscript and the figures	participated in the study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5901021	29461643	R.S.	2	participated in the study concept and design|contributed to drafting the manuscript and the figures	contributed to drafting the manuscript and the figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5901021	29461643	S.H.A.	2	participated in the study concept and design|contributed to drafting the manuscript and the figures	participated in the study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5901021	29461643	S.H.A.	2	participated in the study concept and design|contributed to drafting the manuscript and the figures	contributed to drafting the manuscript and the figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5611491	28979285	CC	2	performed qrt pcr	performed qrt pcr	Performed the experiments	Investigation	YES
5611491	28979285	CH	2	critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5611491	28979285	DH	2	wrote the manuscript|designed the experiments	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5611491	28979285	DH	2	wrote the manuscript|designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5611491	28979285	EL	2	analyzed the transgenic plants	analyzed the transgenic plants	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5611491	28979285	IA	2	identified database oswrky tf gene sequences and designed primers	identified database oswrky tf gene sequences and designed primers	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5611491	28979285	NC	2	wrote the manuscript|performed qrt pcr	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5611491	28979285	NC	2	wrote the manuscript|performed qrt pcr	performed qrt pcr	Performed the experiments	Investigation	YES
5611491	28979285	SB	2	identified database oswrky tf gene sequences and designed primers	identified database oswrky tf gene sequences and designed primers	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5611491	28979285	SL	2	performed qrt pcr	performed qrt pcr	Performed the experiments	Investigation	YES
5611491	28979285	SP	2	identified database oswrky tf gene sequences and designed primers	identified database oswrky tf gene sequences and designed primers	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
3299608	22277306	JB	2	has contributed in the concept and design of the study and has enhanced the intellectual content of the manuscript	has contributed in the concept and design of the study and has enhanced the intellectual content of the manuscript	Conceived and designed the experiments	Conceptualization|Methodology	YES
3299608	22277306	JR	2	has contributed in acquiring the dosimetric data, in analyzing and interpreting this set of data, and in drafting the manuscript	has contributed in acquiring the dosimetric data, in analyzing and interpreting this set of data, and in drafting the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft	YES
3299608	22277306	MH	2	has contributed in the concept and design of the study, in acquiring data, in analyzing and interpreting data, and in drafting the manuscript and has critically contributed to and revised the manuscript, as well as approved the final content of the manuscript	has contributed in the concept and design of the study, in acquiring data, in analyzing and interpreting data, and in drafting the manuscript and has critically contributed to and revised the manuscript, as well as approved the final content of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
3299608	22277306	OE	2	has contributed in the acquisition of radiochemical data and analyzing and interpreting this set of data, as well as in drafting the manuscript	has contributed in the acquisition of radiochemical data and analyzing and interpreting this set of data, as well as in drafting the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft	YES
3299608	22277306	OS	2	has contributed in the concept and design of the study, in analyzing and interpreting data, and in drafting the manuscript, as well as in approving the final content of the manuscript	has contributed in the concept and design of the study, in analyzing and interpreting data, and in drafting the manuscript, as well as in approving the final content of the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Methodology|Resources|Writing - Original Draft	YES
3299608	22277306	PM	2	has contributed in the concept and design of the study, in acquiring preclinical data, and in analyzing and interpreting this set of data, as well as in drafting the manuscript	has contributed in the concept and design of the study, in acquiring preclinical data, and in analyzing and interpreting this set of data, as well as in drafting the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
3299608	22277306	SF	2	is the first author and has taken part in all aspects of preparing the manuscript	is the first author and has taken part in all aspects of preparing the manuscript	Wrote the paper	Writing - Original Draft	YES
3299608	22277306	TG	2	has contributed in acquiring the preclinical data, in analyzing and interpreting this set of data, and in drafting the manuscript	has contributed in acquiring the preclinical data, in analyzing and interpreting this set of data, and in drafting the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft	YES
1762380	17183716	JD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762380	17183716	JD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762380	17183716	JD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762380	17183716	JD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762380	17183716	JS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762380	17183716	JS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762380	17183716	JS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762380	17183716	JS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762380	17183716	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762380	17183716	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762380	17183716	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762380	17183716	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762380	17183716	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762380	17183716	NC	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762380	17183716	NC	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762380	17183716	TD	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762380	17183716	TD	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408120	25905790	CHM	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408120	25905790	HXM	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4408120	25905790	HXW	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4408120	25905790	HXW	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408120	25905790	JNQ	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4408120	25905790	LFG	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408120	25905790	LFG	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408120	25905790	LYX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408120	25905790	LYX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4408120	25905790	LYX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4408120	25905790	LYX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4408120	25905790	PQZ	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4408120	25905790	WW	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408120	25905790	WY	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408120	25905790	XHL	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4408120	25905790	XL	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4408120	25905790	XYX	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4408120	25905790	YX	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4408120	25905790	YX	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5611494	28979280	The author	2	confirms being the sole contributor of this work and approved it for publication	confirms being the sole contributor of this work and approved it for publication	-	-	NO
5418689	28472946	CHC	2	contributed to the development of substantial concept of terminus prediction|contributed to the acquisition of ngs data|developed the pipeline of terminus prediction method and analyzed data|were involved in drafting the manuscript	contributed to the development of substantial concept of terminus prediction	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
5418689	28472946	CHC	2	contributed to the development of substantial concept of terminus prediction|contributed to the acquisition of ngs data|developed the pipeline of terminus prediction method and analyzed data|were involved in drafting the manuscript	contributed to the acquisition of ngs data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5418689	28472946	CHC	2	contributed to the development of substantial concept of terminus prediction|contributed to the acquisition of ngs data|developed the pipeline of terminus prediction method and analyzed data|were involved in drafting the manuscript	developed the pipeline of terminus prediction method and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5418689	28472946	CHC	2	contributed to the development of substantial concept of terminus prediction|contributed to the acquisition of ngs data|developed the pipeline of terminus prediction method and analyzed data|were involved in drafting the manuscript	were involved in drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
5418689	28472946	LY	2	developed the pipeline of terminus prediction method and analyzed data	developed the pipeline of terminus prediction method and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5418689	28472946	MT	2	were involved in critical revision of the manuscript	were involved in critical revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5418689	28472946	MW	2	contributed to the development of substantial concept of terminus prediction|contributed to the acquisition of ngs data|were involved in drafting the manuscript|were involved in critical revision of the manuscript	contributed to the development of substantial concept of terminus prediction	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
5418689	28472946	MW	2	contributed to the development of substantial concept of terminus prediction|contributed to the acquisition of ngs data|were involved in drafting the manuscript|were involved in critical revision of the manuscript	contributed to the acquisition of ngs data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5418689	28472946	MW	2	contributed to the development of substantial concept of terminus prediction|contributed to the acquisition of ngs data|were involved in drafting the manuscript|were involved in critical revision of the manuscript	were involved in drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
5418689	28472946	MW	2	contributed to the development of substantial concept of terminus prediction|contributed to the acquisition of ngs data|were involved in drafting the manuscript|were involved in critical revision of the manuscript	were involved in critical revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5418689	28472946	SCC	2	were involved in critical revision of the manuscript	were involved in critical revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5418689	28472946	VW	2	contributed to the development of substantial concept of terminus prediction	contributed to the development of substantial concept of terminus prediction	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
3311594	22330760	JB	2	participated in the study coordination	participated in the study coordination	-	Project administration	YES
3311594	22330760	MB	2	conceived the study and participated in its design and coordination	conceived the study and participated in its design and coordination	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
3311594	22330760	NA	2	carried out the acquisition and the image analyses	carried out the acquisition and the image analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
3311594	22330760	TC	2	participated in the analyses	participated in the analyses	Analyzed the data	Formal analysis	YES
5901399	29331091	J.A.H.	1	Study concept and design|Drafting manuscript and figures	Study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5901399	29331091	J.A.H.	1	Study concept and design|Drafting manuscript and figures	Drafting manuscript and figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5901399	29331091	J.P.D.	1	Study concept and design|Drafting manuscript and figures	Study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5901399	29331091	J.P.D.	1	Study concept and design|Drafting manuscript and figures	Drafting manuscript and figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5901399	29331091	all authors	1	Data acquisition and analysis	Data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5810340	29091340	All co-authors	2	contributed to the research questions	contributed to the research questions	Conceived and designed the experiments	Conceptualization	YES
5810340	29091340	MK	2	offered technical expertise in developing our search strategy|extracted data and conducted the data analysis	offered technical expertise in developing our search strategy	-	-	NO
5810340	29091340	MK	2	offered technical expertise in developing our search strategy|extracted data and conducted the data analysis	extracted data and conducted the data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5810340	29091340	RK	2	extracted data and conducted the data analysis|drafted the first version of the manuscript and received extensive feedback from all co-authors	extracted data and conducted the data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5810340	29091340	RK	2	extracted data and conducted the data analysis|drafted the first version of the manuscript and received extensive feedback from all co-authors	drafted the first version of the manuscript and received extensive feedback from all co-authors	Wrote the paper	Writing - Original Draft	YES
1762381	17183646	DD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762381	17183646	DD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762381	17183646	DD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762381	17183646	JP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762381	17183646	JP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762381	17183646	JP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3323469	22333272	BF	2	participated in the conception and design of the study	participated in the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3323469	22333272	DPV	2	carried out the in vivo experiments	carried out the in vivo experiments	Performed the experiments	Investigation	YES
3323469	22333272	FP	2	carried out the in vitro and in vivo experiments, data analysis and drafted the manuscript	carried out the in vitro and in vivo experiments, data analysis and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3323469	22333272	GB	2	conceived of the study, participated in its design and coordination, and helped in making the draft of the manuscript	conceived of the study, participated in its design and coordination, and helped in making the draft of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
3323469	22333272	LeR	2	participated in the coordination of the study and reviewed the manuscript	participated in the coordination of the study and reviewed the manuscript	Wrote the paper	Project administration|Writing - Review & Editing	YES
4537707	26301240	Karsten H. Weylandt	2	contributed equally to this work	contributed equally to this work	-	-	NO
4537707	26301240	Simona Serini	2	contributed equally to this work	contributed equally to this work	-	-	NO
5611543	28979270	A-MW	PLoS5	Wrote and edited the paper	Wrote and edited the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5611543	28979270	LR	PLoS5	Contributed reagents/materials/ analysis tools	Contributed reagents/materials/ analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5611543	28979270	MA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote and edited the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5611543	28979270	MA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote and edited the paper	Performed the experiments	Performed the experiments	Investigation	YES
5611543	28979270	MA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote and edited the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5611543	28979270	MA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote and edited the paper	Wrote and edited the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5611543	28979270	RV	PLoS5	Contributed reagents/materials/ analysis tools|Wrote and edited the paper	Contributed reagents/materials/ analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5611543	28979270	RV	PLoS5	Contributed reagents/materials/ analysis tools|Wrote and edited the paper	Wrote and edited the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5611543	28979270	SP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote and edited the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5611543	28979270	SP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote and edited the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5611543	28979270	SP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote and edited the paper	Wrote and edited the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5611543	28979270	VB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote and edited the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5611543	28979270	VB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote and edited the paper	Performed the experiments	Performed the experiments	Investigation	YES
5611543	28979270	VB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote and edited the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5611543	28979270	VB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote and edited the paper	Wrote and edited the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5611543	28979270	YB	PLoS5	Conceived and designed the experiments|Wrote and edited the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5611543	28979270	YB	PLoS5	Conceived and designed the experiments|Wrote and edited the paper	Wrote and edited the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5611543	28979270	ZY	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5611543	28979270	ZZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5901412	29328521	A.B.	1	Acquisition and analysis of data	Acquisition and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5901412	29328521	A.M.R.	1	Acquisition and analysis of data	Acquisition and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5901412	29328521	B.D.	1	Acquisition and analysis of data	Acquisition and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5901412	29328521	D.P.	1	Acquisition and analysis of data	Acquisition and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5901412	29328521	D.S.R.	1	Drafting the text and/or preparing the figures	Drafting the text and/or preparing the figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5901412	29328521	G.C.	1	Acquisition and analysis of data	Acquisition and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5901412	29328521	G.E.	1	Acquisition and analysis of data	Acquisition and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5901412	29328521	G.P.	1	Acquisition and analysis of data	Acquisition and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5901412	29328521	G.S.	1	Acquisition and analysis of data	Acquisition and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5901412	29328521	L.E.	1	Acquisition and analysis of data	Acquisition and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5901412	29328521	L.M.	1	Conception and design of the study|Drafting the text and/or preparing the figures	Conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5901412	29328521	L.M.	1	Conception and design of the study|Drafting the text and/or preparing the figures	Drafting the text and/or preparing the figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5901412	29328521	L.V.	1	Acquisition and analysis of data|Drafting the text and/or preparing the figures	Acquisition and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5901412	29328521	L.V.	1	Acquisition and analysis of data|Drafting the text and/or preparing the figures	Drafting the text and/or preparing the figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5901412	29328521	M.A.	1	Conception and design of the study|Acquisition and analysis of data|Drafting the text and/or preparing the figures	Conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5901412	29328521	M.A.	1	Conception and design of the study|Acquisition and analysis of data|Drafting the text and/or preparing the figures	Acquisition and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5901412	29328521	M.A.	1	Conception and design of the study|Acquisition and analysis of data|Drafting the text and/or preparing the figures	Drafting the text and/or preparing the figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5901412	29328521	M.F.	1	Drafting the text and/or preparing the figures	Drafting the text and/or preparing the figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5901412	29328521	M.G.	1	Acquisition and analysis of data	Acquisition and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5901412	29328521	N.S.	1	Acquisition and analysis of data	Acquisition and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5901412	29328521	P.M.	1	Conception and design of the study|Acquisition and analysis of data|Drafting the text and/or preparing the figures	Conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5901412	29328521	P.M.	1	Conception and design of the study|Acquisition and analysis of data|Drafting the text and/or preparing the figures	Acquisition and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5901412	29328521	P.M.	1	Conception and design of the study|Acquisition and analysis of data|Drafting the text and/or preparing the figures	Drafting the text and/or preparing the figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5901412	29328521	P.S.	1	Acquisition and analysis of data	Acquisition and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5901412	29328521	R.S.	1	Acquisition and analysis of data	Acquisition and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5901412	29328521	V.M.	1	Acquisition and analysis of data	Acquisition and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
1762382	17183663	CA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762382	17183663	CA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762382	17183663	CA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762382	17183663	CA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762382	17183663	CA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762382	17183663	CS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762382	17183663	CS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762382	17183663	GG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762382	17183663	GG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762382	17183663	GG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762382	17183663	GG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762382	17183663	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762382	17183663	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762382	17183663	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762382	17183663	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762382	17183663	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762382	17183663	VG	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762382	17183663	VG	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5810342	29359533	NF-H	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5810342	29359533	RMS	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5418765	28472921	AKU	2	performed the pathologic and histologic examinations	performed the pathologic and histologic examinations	Performed the experiments	Investigation	YES
5418765	28472921	AN	2	performed the pathologic and histologic examinations	performed the pathologic and histologic examinations	Performed the experiments	Investigation	YES
5418765	28472921	JM	2	designed the study, carried out the experiments and data analysis, drafted and finalized the manuscript	designed the study, carried out the experiments and data analysis, drafted and finalized the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5418765	28472921	MHT	2	performed the pathologic and histologic examinations	performed the pathologic and histologic examinations	Performed the experiments	Investigation	YES
5418765	28472921	OD	2	designed the study, carried out the experiments and data analysis, drafted and finalized the manuscript	designed the study, carried out the experiments and data analysis, drafted and finalized the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
3337810	22464315	AA	2	did the fmt-xct imaging	did the fmt-xct imaging	Analyzed the data	Visualization	YES
3337810	22464315	AB	2	designed the experiments|performed the data analysis|have written the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
3337810	22464315	AB	2	designed the experiments|performed the data analysis|have written the manuscript	performed the data analysis	Analyzed the data	Formal analysis	YES
3337810	22464315	AB	2	designed the experiments|performed the data analysis|have written the manuscript	have written the manuscript	Wrote the paper	Writing - Original Draft	YES
3337810	22464315	BDS	2	have written the manuscript|provided the pss-794 contrast agent	have written the manuscript	Wrote the paper	Writing - Original Draft	YES
3337810	22464315	BDS	2	have written the manuscript|provided the pss-794 contrast agent	provided the pss-794 contrast agent	-	-	NO
3337810	22464315	DR	2	designed the experiments|have written the manuscript|provided conceptual input and supervised the research	designed the experiments	Conceived and designed the experiments	Methodology	YES
3337810	22464315	DR	2	designed the experiments|have written the manuscript|provided conceptual input and supervised the research	have written the manuscript	Wrote the paper	Writing - Original Draft	YES
3337810	22464315	DR	2	designed the experiments|have written the manuscript|provided conceptual input and supervised the research	provided conceptual input and supervised the research	Conceived and designed the experiments	Conceptualization|Supervision	YES
3337810	22464315	EH	2	designed the experiments|performed the data analysis	designed the experiments	Conceived and designed the experiments	Methodology	YES
3337810	22464315	EH	2	designed the experiments|performed the data analysis	performed the data analysis	Analyzed the data	Formal analysis	YES
3337810	22464315	VN	2	designed the experiments|provided conceptual input and supervised the research	designed the experiments	Conceived and designed the experiments	Methodology	YES
3337810	22464315	VN	2	designed the experiments|provided conceptual input and supervised the research	provided conceptual input and supervised the research	Conceived and designed the experiments	Conceptualization|Supervision	YES
1762383	17183699	AF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762383	17183699	AF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762383	17183699	AF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762383	17183699	DJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762383	17183699	DJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1762383	17183699	DJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1762383	17183699	DJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1762383	17183699	DJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762383	17183699	KM	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762383	17183699	KM	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762383	17183699	ML	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762383	17183699	ML	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762383	17183699	PH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762383	17183699	PH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762383	17183699	PH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762383	17183699	RA	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762383	17183699	RA	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1762383	17183699	RA	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762383	17183699	RB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762383	17183699	RB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1762383	17183699	RB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762383	17183699	SD	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762383	17183699	SD	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5611544	28979289	all authors	2	contributed to writing the manuscript	contributed to writing the manuscript	Wrote the paper	Writing - Original Draft	YES
4537710	26301243	Each author	2	participated actively in all paper preparation stages	participated actively in all paper preparation stages	-	-	NO
4409017	25909912	AC	PLoS5	Analyzed the data|Revised the manuscript for important conceptual content	Analyzed the data	Analyzed the data	Formal analysis	YES
4409017	25909912	AC	PLoS5	Analyzed the data|Revised the manuscript for important conceptual content	Revised the manuscript for important conceptual content	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
4409017	25909912	AOM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409017	25909912	AOM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409017	25909912	AOM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409017	25909912	AOM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409017	25909912	FM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409017	25909912	TCB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409017	25909912	TCB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4409017	25909912	TCB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
3340309	22444834	CRC	2	carried out the clinical aspects of the study	carried out the clinical aspects of the study	Performed the experiments	Investigation	YES
3340309	22444834	EOA	2	designed the study|drafted the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
3340309	22444834	EOA	2	designed the study|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
3340309	22444834	FET	2	carried out the analytical aspects of the study including statistical analysis and modelling	carried out the analytical aspects of the study including statistical analysis and modelling	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
3340309	22444834	KBC	2	carried out the clinical aspects of the study|carried out the analytical aspects of the study including statistical analysis and modelling|drafted the manuscript	carried out the clinical aspects of the study	Performed the experiments	Investigation	YES
3340309	22444834	KBC	2	carried out the clinical aspects of the study|carried out the analytical aspects of the study including statistical analysis and modelling|drafted the manuscript	carried out the analytical aspects of the study including statistical analysis and modelling	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
3340309	22444834	KBC	2	carried out the clinical aspects of the study|carried out the analytical aspects of the study including statistical analysis and modelling|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
3340309	22444834	LMK	2	carried out the clinical aspects of the study	carried out the clinical aspects of the study	Performed the experiments	Investigation	YES
3340309	22444834	LR	2	designed the study|carried out the analytical aspects of the study including statistical analysis and modelling|drafted the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
3340309	22444834	LR	2	designed the study|carried out the analytical aspects of the study including statistical analysis and modelling|drafted the manuscript	carried out the analytical aspects of the study including statistical analysis and modelling	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
3340309	22444834	LR	2	designed the study|carried out the analytical aspects of the study including statistical analysis and modelling|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5810343	29314670	All authors	2	contributed to model interpretation|were involved in revising the manuscript	contributed to model interpretation	Performed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5810343	29314670	All authors	2	contributed to model interpretation|were involved in revising the manuscript	were involved in revising the manuscript	Wrote the paper	Writing - Review & Editing	YES
5810343	29314670	CEH	2	provided behavioural parameter estimates	provided behavioural parameter estimates	Analyzed the data	Formal analysis	YES
5810343	29314670	DW	2	critically reviewed the modelling	critically reviewed the modelling	Performed the experiments	Methodology	YES
5810343	29314670	JD	2	conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5810343	29314670	MH	2	conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5810343	29314670	MS	2	provided behavioural parameter estimates	provided behavioural parameter estimates	Analyzed the data	Formal analysis	YES
5810343	29314670	NS	2	performed the modelling and drafted the manuscript|conceived the study	performed the modelling and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5810343	29314670	NS	2	performed the modelling and drafted the manuscript|conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5810343	29314670	OK	2	critically reviewed the modelling	critically reviewed the modelling	Performed the experiments	Methodology	YES
5418769	28472937	A.L.V.	2	contributed with sample collection and manuscript preparation	contributed with sample collection and manuscript preparation	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Resources|Writing - Original Draft	YES
5418769	28472937	C.F.	2	performed illumina sequencing and reviewed the manuscript	performed illumina sequencing and reviewed the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5418769	28472937	D.A.M.	2	performed data analyses/interpretation and drafted the manuscript	performed data analyses/interpretation and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5418769	28472937	P.A.B.	2	contributed with sample collection, data interpretation and manuscript preparation	contributed with sample collection, data interpretation and manuscript preparation	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft	YES
5418769	28472937	R.S.	2	contributed with data analyses and manuscript preparation	contributed with data analyses and manuscript preparation	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
5418769	28472937	T.E.P.	2	designed the work, contributed with data analyses, performed data interpretation and wrote the manuscript	designed the work, contributed with data analyses, performed data interpretation and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
1762384	17183644	DK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762384	17183644	DK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762384	17183644	DK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762384	17183644	KL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1762384	17183644	NP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1762384	17183644	RV	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762384	17183644	RV	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762384	17183644	RV	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762384	17183644	SL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762384	17183644	SL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762384	17183644	VZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762384	17183644	VZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762384	17183644	VZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762384	17183644	YH	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4537711	26301248	Christoph Riegger	PLoS52	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
4537711	26301248	Joseph Schwager	PLoS52	contributed equally to this work|designed the experiments|analysed the data|has written the paper	contributed equally to this work	-	-	NO
4537711	26301248	Joseph Schwager	PLoS52	contributed equally to this work|designed the experiments|analysed the data|has written the paper	designed the experiments	Conceived and designed the experiments	Methodology	YES
4537711	26301248	Joseph Schwager	PLoS52	contributed equally to this work|designed the experiments|analysed the data|has written the paper	analysed the data	Analyzed the data	Formal analysis	YES
4537711	26301248	Joseph Schwager	PLoS52	contributed equally to this work|designed the experiments|analysed the data|has written the paper	has written the paper	Wrote the paper	Writing - Original Draft	YES
4537711	26301248	Nathalie Richard	PLoS52	contributed equally to this work|designed the experiments|performed the experiments|analysed the data	contributed equally to this work	-	-	NO
4537711	26301248	Nathalie Richard	PLoS52	contributed equally to this work|designed the experiments|performed the experiments|analysed the data	designed the experiments	Conceived and designed the experiments	Methodology	YES
4537711	26301248	Nathalie Richard	PLoS52	contributed equally to this work|designed the experiments|performed the experiments|analysed the data	performed the experiments	Performed the experiments	Investigation	YES
4537711	26301248	Nathalie Richard	PLoS52	contributed equally to this work|designed the experiments|performed the experiments|analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
4537711	26301248	Norman Salem	PLoS52	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
4409037	25910083	ET	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409037	25910083	ET	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409037	25910083	ET	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409037	25910083	ET	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409037	25910083	ET	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409037	25910083	JCY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409037	25910083	JCY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409037	25910083	JCY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409037	25910083	JCY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409037	25910083	JCY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409037	25910083	PES	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409037	25910083	PES	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409037	25910083	PES	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409037	25910083	PES	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409037	25910083	PES	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3348032	22455873	CFMM	2	contributed in conception and design of the mice study|contributed in to the acquiring of pet data	contributed in conception and design of the mice study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3348032	22455873	CFMM	2	contributed in conception and design of the mice study|contributed in to the acquiring of pet data	contributed in to the acquiring of pet data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
3348032	22455873	Each author	2	contributed significantly to the submitted work	contributed significantly to the submitted work	-	-	NO
3348032	22455873	FEF	2	were in charge of the study, acquiring, analyzing, interpreting the data and drafting the manuscript	were in charge of the study, acquiring, analyzing, interpreting the data and drafting the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3348032	22455873	JE	2	was in charge of the radiochemistry	was in charge of the radiochemistry	-	-	NO
3348032	22455873	MCH	2	was responsible for pet image reconstruction and contributed to data analysis	was responsible for pet image reconstruction and contributed to data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
3348032	22455873	NHH	2	contributed in conception and design of the mice study	contributed in conception and design of the mice study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3348032	22455873	PET	2	contributed to the design of the study, analysis and interpretation of data	contributed to the design of the study, analysis and interpretation of data	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Methodology|Resources	YES
3348032	22455873	RAV	2	contributed to the design of the study, analysis and interpretation of all data and in drafting the manuscript	contributed to the design of the study, analysis and interpretation of all data and in drafting the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Original Draft	YES
3348032	22455873	SS	2	were in charge of the study, acquiring, analyzing, interpreting the data and drafting the manuscript	were in charge of the study, acquiring, analyzing, interpreting the data and drafting the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3348032	22455873	YT	2	analyzed the rat plasma data	analyzed the rat plasma data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5611565	28979274	GS	2	drafted the manuscript|edited the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5611565	28979274	GS	2	drafted the manuscript|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5611565	28979274	HP	2	edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5611565	28979274	JS	2	collected the samples|performed the real time pcr for the expression analysis	collected the samples	Performed the experiments	Investigation	YES
5611565	28979274	JS	2	collected the samples|performed the real time pcr for the expression analysis	performed the real time pcr for the expression analysis	Performed the experiments	Investigation	YES
5611565	28979274	KD	2	collected the samples|performed the real time pcr for the expression analysis	collected the samples	Performed the experiments	Investigation	YES
5611565	28979274	KD	2	collected the samples|performed the real time pcr for the expression analysis	performed the real time pcr for the expression analysis	Performed the experiments	Investigation	YES
5611565	28979274	KS	2	performed the real time pcr for the expression analysis	performed the real time pcr for the expression analysis	Performed the experiments	Investigation	YES
5611565	28979274	MJ	2	performed the biochemical characterization of the collected samples	performed the biochemical characterization of the collected samples	Performed the experiments	Investigation	YES
5611565	28979274	MS	2	performed the biochemical characterization of the collected samples	performed the biochemical characterization of the collected samples	Performed the experiments	Investigation	YES
5611565	28979274	RK	2	conceptualized the ideas and lay down the experiment|drafted the manuscript	conceptualized the ideas and lay down the experiment	Conceived and designed the experiments	Conceptualization	YES
5611565	28979274	RK	2	conceptualized the ideas and lay down the experiment|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5611565	28979274	SG	2	conceptualized the ideas and lay down the experiment	conceptualized the ideas and lay down the experiment	Conceived and designed the experiments	Conceptualization	YES
5611565	28979274	SP	2	conceptualized the ideas and lay down the experiment|edited the manuscript	conceptualized the ideas and lay down the experiment	Conceived and designed the experiments	Conceptualization	YES
5611565	28979274	SP	2	conceptualized the ideas and lay down the experiment|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5611565	28979274	UM	2	performed the biochemical characterization of the collected samples	performed the biochemical characterization of the collected samples	Performed the experiments	Investigation	YES
5611565	28979274	VC	2	drafted the manuscript|edited the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5611565	28979274	VC	2	drafted the manuscript|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
6032831	29604233	H.B.W.L.	1	Study concept and design|Data acquisition and analysis	Study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6032831	29604233	H.B.W.L.	1	Study concept and design|Data acquisition and analysis	Data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6032831	29604233	H.J.S.	1	Data acquisition and analysis	Data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6032831	29604233	J.L.F.	1	Study concept and design|Data acquisition and analysis	Study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6032831	29604233	J.L.F.	1	Study concept and design|Data acquisition and analysis	Data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6032831	29604233	S.P.C.	1	Study concept and design|Data acquisition and analysis	Study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6032831	29604233	S.P.C.	1	Study concept and design|Data acquisition and analysis	Data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6032831	29604233	all authors	1	Drafting the text and figures	Drafting the text and figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5810344	29327442	CL	2	contributed to the study design|provided statistical support	contributed to the study design	Conceived and designed the experiments	Methodology	YES
5810344	29327442	CL	2	contributed to the study design|provided statistical support	provided statistical support	Analyzed the data	Formal analysis	YES
5810344	29327442	CW	2	conceived the study|contributed to the study design	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5810344	29327442	CW	2	conceived the study|contributed to the study design	contributed to the study design	Conceived and designed the experiments	Methodology	YES
5810344	29327442	JT	2	conceived the study|contributed to the study design	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5810344	29327442	JT	2	conceived the study|contributed to the study design	contributed to the study design	Conceived and designed the experiments	Methodology	YES
5810344	29327442	MS	2	contributed to the study design|provided statistical support	contributed to the study design	Conceived and designed the experiments	Methodology	YES
5810344	29327442	MS	2	contributed to the study design|provided statistical support	provided statistical support	Analyzed the data	Formal analysis	YES
5810344	29327442	RF	2	contributed to the study design	contributed to the study design	Conceived and designed the experiments	Methodology	YES
5810344	29327442	SP	2	provided statistical support	provided statistical support	Analyzed the data	Formal analysis	YES
5810344	29327442	WT	2	contributed to the study design|provided statistical support	contributed to the study design	Conceived and designed the experiments	Methodology	YES
5810344	29327442	WT	2	contributed to the study design|provided statistical support	provided statistical support	Analyzed the data	Formal analysis	YES
1762385	17183703	AB	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762385	17183703	AB	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762385	17183703	AE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762385	17183703	AE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762385	17183703	AE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762385	17183703	BA	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762385	17183703	BA	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762385	17183703	BU	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762385	17183703	BU	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762385	17183703	EA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762385	17183703	EA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762385	17183703	EA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762385	17183703	FN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762385	17183703	FN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762385	17183703	FN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762385	17183703	FN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762385	17183703	FS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762385	17183703	FS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762385	17183703	FS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762385	17183703	GM	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762385	17183703	GM	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762385	17183703	MG	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762385	17183703	MG	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762385	17183703	MS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762385	17183703	MU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762385	17183703	MU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762385	17183703	MU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762385	17183703	NF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762385	17183703	NF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762385	17183703	NF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762385	17183703	NF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762385	17183703	RZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762385	17183703	RZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762385	17183703	RZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762385	17183703	SF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762385	17183703	SF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762385	17183703	SF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762385	17183703	SM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762385	17183703	UB	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762385	17183703	UB	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762385	17183703	UM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762385	17183703	UM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762385	17183703	UM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762385	17183703	ZR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762385	17183703	ZR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762385	17183703	ZR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409040	25909963	AI	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409040	25909963	AJR	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4409040	25909963	AJR	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4409040	25909963	AJR	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409040	25909963	AS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4409040	25909963	AS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4409040	25909963	AS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409040	25909963	AVC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409040	25909963	AVC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409040	25909963	AVC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409040	25909963	AVC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409040	25909963	BJJ	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4409040	25909963	BJJ	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409040	25909963	BW	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409040	25909963	LCD	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4409040	25909963	LCD	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409040	25909963	MS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4409040	25909963	MS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409040	25909963	RS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4409040	25909963	RS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409040	25909963	SAY	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4409040	25909963	SAY	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409040	25909963	SBS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4409040	25909963	SBS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409040	25909963	SGJ	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409040	25909963	SGJ	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409040	25909963	SK	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409040	25909963	XL	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4409040	25909963	XL	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5418855	28472924	All co-authors	2	participated in preparation of the final manuscript that was read and approved by all authors	participated in preparation of the final manuscript that was read and approved by all authors	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5418855	28472924	BH	2	contributed in design of the study and participated in preparation of the manuscript	contributed in design of the study and participated in preparation of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5418855	28472924	HS	2	contributed all challenge materials and performed rt-qpcr measurements of viral loads	contributed all challenge materials and performed rt-qpcr measurements of viral loads	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5418855	28472924	IOE	2	performed major part of the cdna synthesis, carried out major part of rt qpcr and analysed the rt-qpcr results	performed major part of the cdna synthesis, carried out major part of rt qpcr and analysed the rt-qpcr results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5418855	28472924	NTW	2	carried out major part of in silico analyses including blast analyses, predictions of target genes and promotor searches	carried out major part of in silico analyses including blast analyses, predictions of target genes and promotor searches	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5418855	28472924	OA	2	performed major part of the processing of the deep sequencing data and deseq2 analysis	performed major part of the processing of the deep sequencing data and deseq2 analysis	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5418855	28472924	RA	2	conceived and coordinated the study|worked on all aspects of the study including extraction of total rna, cdna synthesis, rt qpcr, the bioinformatics analyses and drafted the manuscript	conceived and coordinated the study	Conceived and designed the experiments	Conceptualization|Project administration	YES
5418855	28472924	RA	2	conceived and coordinated the study|worked on all aspects of the study including extraction of total rna, cdna synthesis, rt qpcr, the bioinformatics analyses and drafted the manuscript	worked on all aspects of the study including extraction of total rna, cdna synthesis, rt qpcr, the bioinformatics analyses and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3349514	22404895	AAL	2	critically reviewed the manuscript and approved the final content of the manuscript	critically reviewed the manuscript and approved the final content of the manuscript	Wrote the paper	Writing - Review & Editing	YES
3349514	22404895	All authors	2	reviewed the collected data and interpretation, provided feedback for further research during the study and approved the final submitted version of this manuscript	reviewed the collected data and interpretation, provided feedback for further research during the study and approved the final submitted version of this manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
3349514	22404895	FHPvV	2	performed data analysis and data interpretation, implemented some of the tools to perform image registrations, contributed in the study design and is the main author of the manuscript	performed data analysis and data interpretation, implemented some of the tools to perform image registrations, contributed in the study design and is the main author of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Visualization|Writing - Original Draft	YES
3349514	22404895	JN	2	implemented regisrigid, contributed to the intellectual content and critically reviewed manuscript	implemented regisrigid, contributed to the intellectual content and critically reviewed manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
3349514	22404895	LMV	2	provided pet image data and reviewed the manuscript	provided pet image data and reviewed the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Visualization|Writing - Review & Editing	YES
3349514	22404895	MIRIT	2	contributed to the intellectual content and critically reviewed manuscript	contributed to the intellectual content and critically reviewed manuscript	Wrote the paper	Writing - Review & Editing	YES
3349514	22404895	PvB	2	performed data analysis and data interpretation	performed data analysis and data interpretation	Analyzed the data	Formal analysis	YES
3349514	22404895	RB	2	performed a study design, supervised the project and reviewed and approved the final content of the manuscript	performed a study design, supervised the project and reviewed and approved the final content of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Supervision|Writing - Review & Editing	YES
6152589	30077530	AH	2	generated the idea, contributed to draft and to critically reviewed the manuscript|interpreted the data	generated the idea, contributed to draft and to critically reviewed the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
6152589	30077530	AH	2	generated the idea, contributed to draft and to critically reviewed the manuscript|interpreted the data	interpreted the data	Analyzed the data	Formal analysis	YES
6152589	30077530	AV	2	generated the idea, contributed to draft and to critically reviewed the manuscript|interpreted the data	generated the idea, contributed to draft and to critically reviewed the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
6152589	30077530	AV	2	generated the idea, contributed to draft and to critically reviewed the manuscript|interpreted the data	interpreted the data	Analyzed the data	Formal analysis	YES
6152589	30077530	COR	2	acquired the data and critically reviewed the manuscript|organized the final dataset	acquired the data and critically reviewed the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
6152589	30077530	COR	2	acquired the data and critically reviewed the manuscript|organized the final dataset	organized the final dataset	-	-	NO
6152589	30077530	DB	2	acquired the data and critically reviewed the manuscript|organized the final dataset|interpreted the data	acquired the data and critically reviewed the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
6152589	30077530	DB	2	acquired the data and critically reviewed the manuscript|organized the final dataset|interpreted the data	organized the final dataset	-	-	NO
6152589	30077530	DB	2	acquired the data and critically reviewed the manuscript|organized the final dataset|interpreted the data	interpreted the data	Analyzed the data	Formal analysis	YES
6152589	30077530	FDA	2	generated the idea, contributed to draft and to critically reviewed the manuscript|performed the statistical analyses	generated the idea, contributed to draft and to critically reviewed the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
6152589	30077530	FDA	2	generated the idea, contributed to draft and to critically reviewed the manuscript|performed the statistical analyses	performed the statistical analyses	Analyzed the data	Formal analysis	YES
6152589	30077530	FDS	2	interpreted the data	interpreted the data	Analyzed the data	Formal analysis	YES
6152589	30077530	IK	2	acquired the data and critically reviewed the manuscript|organized the final dataset	acquired the data and critically reviewed the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
6152589	30077530	IK	2	acquired the data and critically reviewed the manuscript|organized the final dataset	organized the final dataset	-	-	NO
6152589	30077530	JD	2	generated the idea, contributed to draft and to critically reviewed the manuscript|interpreted the data	generated the idea, contributed to draft and to critically reviewed the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
6152589	30077530	JD	2	generated the idea, contributed to draft and to critically reviewed the manuscript|interpreted the data	interpreted the data	Analyzed the data	Formal analysis	YES
6152589	30077530	MO	2	generated the idea, contributed to draft and to critically reviewed the manuscript|acquired the data and critically reviewed the manuscript|performed the statistical analyses|interpreted the data	generated the idea, contributed to draft and to critically reviewed the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
6152589	30077530	MO	2	generated the idea, contributed to draft and to critically reviewed the manuscript|acquired the data and critically reviewed the manuscript|performed the statistical analyses|interpreted the data	acquired the data and critically reviewed the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
6152589	30077530	MO	2	generated the idea, contributed to draft and to critically reviewed the manuscript|acquired the data and critically reviewed the manuscript|performed the statistical analyses|interpreted the data	performed the statistical analyses	Analyzed the data	Formal analysis	YES
6152589	30077530	MO	2	generated the idea, contributed to draft and to critically reviewed the manuscript|acquired the data and critically reviewed the manuscript|performed the statistical analyses|interpreted the data	interpreted the data	Analyzed the data	Formal analysis	YES
6152589	30077530	MP	2	acquired the data and critically reviewed the manuscript|organized the final dataset|interpreted the data	acquired the data and critically reviewed the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
6152589	30077530	MP	2	acquired the data and critically reviewed the manuscript|organized the final dataset|interpreted the data	organized the final dataset	-	-	NO
6152589	30077530	MP	2	acquired the data and critically reviewed the manuscript|organized the final dataset|interpreted the data	interpreted the data	Analyzed the data	Formal analysis	YES
6152589	30077530	ND	2	generated the idea, contributed to draft and to critically reviewed the manuscript|interpreted the data	generated the idea, contributed to draft and to critically reviewed the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
6152589	30077530	ND	2	generated the idea, contributed to draft and to critically reviewed the manuscript|interpreted the data	interpreted the data	Analyzed the data	Formal analysis	YES
6152589	30077530	SJH	2	generated the idea, contributed to draft and to critically reviewed the manuscript|interpreted the data	generated the idea, contributed to draft and to critically reviewed the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
6152589	30077530	SJH	2	generated the idea, contributed to draft and to critically reviewed the manuscript|interpreted the data	interpreted the data	Analyzed the data	Formal analysis	YES
6152589	30077530	SM	2	generated the idea, contributed to draft and to critically reviewed the manuscript|acquired the data and critically reviewed the manuscript|performed the statistical analyses|interpreted the data	generated the idea, contributed to draft and to critically reviewed the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
6152589	30077530	SM	2	generated the idea, contributed to draft and to critically reviewed the manuscript|acquired the data and critically reviewed the manuscript|performed the statistical analyses|interpreted the data	acquired the data and critically reviewed the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
6152589	30077530	SM	2	generated the idea, contributed to draft and to critically reviewed the manuscript|acquired the data and critically reviewed the manuscript|performed the statistical analyses|interpreted the data	performed the statistical analyses	Analyzed the data	Formal analysis	YES
6152589	30077530	SM	2	generated the idea, contributed to draft and to critically reviewed the manuscript|acquired the data and critically reviewed the manuscript|performed the statistical analyses|interpreted the data	interpreted the data	Analyzed the data	Formal analysis	YES
5611596	28979271	AF	7	design and planning of the research; sample collection, analysis and interpretation of the dataset	design and planning of the research; sample collection, analysis and interpretation of the dataset	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5611596	28979271	AR	7	analysis and interpretation of the dataset, elaboration of the draft, critical review of the content and construction of the final version of the manuscript	analysis and interpretation of the dataset, elaboration of the draft, critical review of the content and construction of the final version of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5611596	28979271	CK	7	critical review of the content and elaboration of the manuscript draft	critical review of the content and elaboration of the manuscript draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5611596	28979271	CQ	7	analysis and interpretation of the dataset, elaboration of the draft, critical review of the content and construction of the final version of the manuscript	analysis and interpretation of the dataset, elaboration of the draft, critical review of the content and construction of the final version of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5611596	28979271	JS	7	analysis and interpretation of the dataset, elaborating of the draft, critical review of the content and construction of the final version of the manuscript	analysis and interpretation of the dataset, elaborating of the draft, critical review of the content and construction of the final version of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5611596	28979271	MF	7	analysis and interpretation of the dataset, elaboration of the draft, critical review of the content and construction of the final version of the manuscript	analysis and interpretation of the dataset, elaboration of the draft, critical review of the content and construction of the final version of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5611596	28979271	MS	7	design and planning of the research, analysis and interpretation of the dataset	design and planning of the research, analysis and interpretation of the dataset	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5611596	28979271	PS	7	design and planning of the research, analysis and interpretation of the dataset	design and planning of the research, analysis and interpretation of the dataset	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5611596	28979271	RL	7	analysis and interpretation of the dataset, elaboration of the draft, critical review of the content and construction of the final version of the manuscript	analysis and interpretation of the dataset, elaboration of the draft, critical review of the content and construction of the final version of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5810346	29285883	EF	2	conceived the project	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5810346	29285883	EPM	2	led laboratory analyses and contributed to the manuscript	led laboratory analyses and contributed to the manuscript	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5810346	29285883	JRH	2	conceived the project	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5810346	29285883	OL	2	led laboratory analyses and contributed to the manuscript	led laboratory analyses and contributed to the manuscript	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5810346	29285883	SDM	2	contributed to the interpretation of findings and to the final drafting of the manuscript	contributed to the interpretation of findings and to the final drafting of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4409043	25909365	APB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409043	25909365	APB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409043	25909365	APB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409043	25909365	APB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409043	25909365	CPM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409043	25909365	CPM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409043	25909365	CS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409043	25909365	FQ	PLoS5	Conceived and designed the experiments|Analyzed the data|Performed the field survey	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409043	25909365	FQ	PLoS5	Conceived and designed the experiments|Analyzed the data|Performed the field survey	Analyzed the data	Analyzed the data	Formal analysis	YES
4409043	25909365	FQ	PLoS5	Conceived and designed the experiments|Analyzed the data|Performed the field survey	Performed the field survey	Performed the experiments	Investigation	YES
4409043	25909365	KV	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409043	25909365	NN	PLoS5	Analyzed the data|Performed the field survey	Analyzed the data	Analyzed the data	Formal analysis	YES
4409043	25909365	NN	PLoS5	Analyzed the data|Performed the field survey	Performed the field survey	Performed the experiments	Investigation	YES
4409043	25909365	PN	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409043	25909365	SG	PLoS5	Conceived and designed the experiments|Wrote the paper|Performed the field survey	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409043	25909365	SG	PLoS5	Conceived and designed the experiments|Wrote the paper|Performed the field survey	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409043	25909365	SG	PLoS5	Conceived and designed the experiments|Wrote the paper|Performed the field survey	Performed the field survey	Performed the experiments	Investigation	YES
4409043	25909365	YB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409043	25909365	YB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409043	25909365	YB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409043	25909365	YB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6175096	30048006	H.Y.K.	1	Conception and design of the study	Conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6175096	30048006	K.-W.O.	1	Conception and design of the study	Conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6175096	30048006	S.H.K.	1	Conception and design of the study	Conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6175096	30048006	all authors	1	Acquisition and analysis of data	Acquisition and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
1762386	17183648	AW	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762386	17183648	AW	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762386	17183648	GH	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762386	17183648	GH	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762386	17183648	HM	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762386	17183648	HM	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762386	17183648	MH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762386	17183648	MH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762386	17183648	MH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762386	17183648	MT	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762386	17183648	MT	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762386	17183648	SM	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762386	17183648	SM	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762386	17183648	TH	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762386	17183648	TH	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762386	17183648	TH	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762386	17183648	WH	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762386	17183648	WH	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6236127	30195843	AC	2	revised the manuscript and participated in the scientific discussion during the study	revised the manuscript and participated in the scientific discussion during the study	Wrote the paper	Writing - Review & Editing	YES
6236127	30195843	AS	2	designed the study protocol, performed data acquisition, performed statistical analyses and drafted the manuscript	designed the study protocol, performed data acquisition, performed statistical analyses and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
6236127	30195843	AV	2	revised the manuscript and participated in the scientific discussion during the study	revised the manuscript and participated in the scientific discussion during the study	Wrote the paper	Writing - Review & Editing	YES
6236127	30195843	GH	2	revised the manuscript and participated in the scientific discussion during the study	revised the manuscript and participated in the scientific discussion during the study	Wrote the paper	Writing - Review & Editing	YES
6236127	30195843	HT	2	revised the manuscript and participated in the scientific discussion during the study	revised the manuscript and participated in the scientific discussion during the study	Wrote the paper	Writing - Review & Editing	YES
6236127	30195843	IE	2	designed the study protocol, performed data acquisition, performed statistical analyses and drafted the manuscript	designed the study protocol, performed data acquisition, performed statistical analyses and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
6236127	30195843	JK	2	revised the manuscript and participated in the scientific discussion during the study	revised the manuscript and participated in the scientific discussion during the study	Wrote the paper	Writing - Review & Editing	YES
6236127	30195843	JL	2	revised the manuscript and participated in the scientific discussion during the study	revised the manuscript and participated in the scientific discussion during the study	Wrote the paper	Writing - Review & Editing	YES
6236127	30195843	JU	2	performed statistical analyses	performed statistical analyses	Analyzed the data	Formal analysis	YES
6236127	30195843	PL	2	performed data acquisition/analysis and revised the manuscript	performed data acquisition/analysis and revised the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
6236127	30195843	SB	2	designed the study protocol, performed data acquisition, performed statistical analyses and drafted the manuscript	designed the study protocol, performed data acquisition, performed statistical analyses and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
6236127	30195843	TL	2	performed data acquisition/analysis and revised the manuscript	performed data acquisition/analysis and revised the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
6236127	30195843	TS	2	designed the study protocol, performed data acquisition, performed statistical analyses and drafted the manuscript	designed the study protocol, performed data acquisition, performed statistical analyses and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
6236127	30195843	UR	2	revised the manuscript and participated in the scientific discussion during the study	revised the manuscript and participated in the scientific discussion during the study	Wrote the paper	Writing - Review & Editing	YES
3350394	22524272	AA	2	conceived the study and participated in the study design and result interpretation	conceived the study and participated in the study design and result interpretation	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
3350394	22524272	AJ	2	participated in the study design, performed the statistical analysis and drafted the manuscript	participated in the study design, performed the statistical analysis and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3350394	22524272	CH	2	participated in the study design, coordination and interpretation of study results	participated in the study design, coordination and interpretation of study results	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology|Project administration	YES
3350394	22524272	GA	2	conceived the study and participated in the study design and interpretation	conceived the study and participated in the study design and interpretation	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
3350394	22524272	JA	2	performed the radiochemistry work and participated in the data interpretation and description	performed the radiochemistry work and participated in the data interpretation and description	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3350394	22524272	KV	2	participated in the pet image analysis and method description	participated in the pet image analysis and method description	Performed the experiments|Analyzed the data	Visualization	YES
3350394	22524272	LF	2	conceived the study and participated in the interpretation of results and manuscript writing	conceived the study and participated in the interpretation of results and manuscript writing	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
3350394	22524272	PET	2	image analyses and statistical analysis and contributed to the data interpretation and method description	image analyses and statistical analysis and contributed to the data interpretation and method description	Performed the experiments|Analyzed the data	Formal analysis|Visualization	YES
3350394	22524272	PJ	2	designed the mr protocol and performed the mr analysis	designed the mr protocol and performed the mr analysis	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3350394	22524272	PS	2	participated in the study design and carried out the pet examinations	participated in the study design and carried out the pet examinations	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5611624	28979273	AdS	7	performed the ros, antioxidants and relative Rubisco content analyses; contributed to draft writing	performed the ros, antioxidants and relative Rubisco content analyses; contributed to draft writing	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5611624	28979273	C-OO	7	contributed in designing of the experiment, supervision and monitoring, manuscript writing	contributed in designing of the experiment, supervision and monitoring, manuscript writing	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Supervision|Writing - Original Draft	YES
5611624	28979273	CS	7	performed the ros, antioxidants and relative Rubisco content analyses; contributed to draft writing	performed the ros, antioxidants and relative Rubisco content analyses; contributed to draft writing	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5611624	28979273	ER	7	contributed in designing of the experiment, supervision and monitoring, manuscript writing	contributed in designing of the experiment, supervision and monitoring, manuscript writing	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Supervision|Writing - Original Draft	YES
5611624	28979273	FF	7	contributed in supervision of ros, antioxidants and relative Rubisco content analyses	contributed in supervision of ros, antioxidants and relative Rubisco content analyses	Analyzed the data	Formal analysis|Supervision	YES
5611624	28979273	KK	7	contributed in designing of the experiment, supervision and monitoring, biochemical analyses; critically revised the manuscript	contributed in designing of the experiment, supervision and monitoring, biochemical analyses; critically revised the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Supervision|Writing - Review & Editing	YES
5611624	28979273	MH	7	contributed in planning and designing of the experiment, experimental set up, all data recording and sampling, biochemical analyses, statistical analysis and writing of the manuscript	contributed in planning and designing of the experiment, experimental set up, all data recording and sampling, biochemical analyses, statistical analysis and writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
5418858	28472930	AMDS	2	conceived the study and designed the experiments|wrote the manuscript	conceived the study and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5418858	28472930	AMDS	2	conceived the study and designed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5418858	28472930	APSS	2	performed phage infection, virions purification, biofilm assays and one-step growth curve experiments|generated electron microscopy images	performed phage infection, virions purification, biofilm assays and one-step growth curve experiments	Performed the experiments	Investigation	YES
5418858	28472930	APSS	2	performed phage infection, virions purification, biofilm assays and one-step growth curve experiments|generated electron microscopy images	generated electron microscopy images	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
5418858	28472930	CU	2	guided the work with the vocs database	guided the work with the vocs database	Contributed reagents/materials/analysis tools	Software|Supervision	YES
5418858	28472930	DA	2	conceived the study and designed the experiments|performed genomic characterization and bioinformatics analyses|wrote the manuscript	conceived the study and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5418858	28472930	DA	2	conceived the study and designed the experiments|performed genomic characterization and bioinformatics analyses|wrote the manuscript	performed genomic characterization and bioinformatics analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5418858	28472930	DA	2	conceived the study and designed the experiments|performed genomic characterization and bioinformatics analyses|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5418858	28472930	EWK	2	generated electron microscopy images	generated electron microscopy images	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
5418858	28472930	JCS	2	conceived the study and designed the experiments|wrote the manuscript	conceived the study and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5418858	28472930	JCS	2	conceived the study and designed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5418858	28472930	KCL	2	isolated the new phages from composting|performed phage dna isolation and sequencing	isolated the new phages from composting	Performed the experiments	Investigation	YES
5418858	28472930	KCL	2	isolated the new phages from composting|performed phage dna isolation and sequencing	performed phage dna isolation and sequencing	Performed the experiments	Investigation	YES
5418858	28472930	LFM	2	performed phage dna isolation and sequencing|performed phage infection, virions purification, biofilm assays and one-step growth curve experiments	performed phage dna isolation and sequencing	Performed the experiments	Investigation	YES
5418858	28472930	LFM	2	performed phage dna isolation and sequencing|performed phage infection, virions purification, biofilm assays and one-step growth curve experiments	performed phage infection, virions purification, biofilm assays and one-step growth curve experiments	Performed the experiments	Investigation	YES
5418858	28472930	LPA	2	isolated the new phages from composting|performed phage dna isolation and sequencing	isolated the new phages from composting	Performed the experiments	Investigation	YES
5418858	28472930	LPA	2	isolated the new phages from composting|performed phage dna isolation and sequencing	performed phage dna isolation and sequencing	Performed the experiments	Investigation	YES
5418858	28472930	RBQ	2	performed phage infection, virions purification, biofilm assays and one-step growth curve experiments	performed phage infection, virions purification, biofilm assays and one-step growth curve experiments	Performed the experiments	Investigation	YES
4537716	26301245	Birgit Weyand	2	contributed equally to this work	contributed equally to this work	-	-	NO
4537716	26301245	Meir Israelowitz	2	contributed equally to this work	contributed equally to this work	-	-	NO
4409046	25909813	ALT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409046	25909813	ALT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409046	25909813	ALT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409046	25909813	ALT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409046	25909813	FD	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409046	25909813	FD	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409046	25909813	FL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409046	25909813	JCM	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409046	25909813	JCM	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409046	25909813	JIS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409046	25909813	JM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409046	25909813	MF	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4409046	25909813	MF	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409046	25909813	MG	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409046	25909813	MG	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409046	25909813	RM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409046	25909813	RM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409046	25909813	RM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409046	25909813	RM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762387	17183684	AB	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762387	17183684	HN	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762387	17183684	HN	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762387	17183684	HV	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762387	17183684	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762387	17183684	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762387	17183684	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762387	17183684	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762387	17183684	PM	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762387	17183684	PM	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762387	17183684	SF	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1762387	17183684	SF	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762387	17183684	SH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1762387	17183684	VB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
3351026	22464278	HJW	2	provided important advice in the conception of the study, gave advice in the interpretation of the data, and critically reviewed the manuscript	provided important advice in the conception of the study, gave advice in the interpretation of the data, and critically reviewed the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Resources|Writing - Review & Editing	YES
3351026	22464278	JN	2	developed the study concept	developed the study concept	Conceived and designed the experiments	Conceptualization	YES
3351026	22464278	JP	2	performed all nmr measurements and evaluated the data	performed all nmr measurements and evaluated the data	Performed the experiments	Investigation	YES
3351026	22464278	PET	2	imaging, and pet data analysis	imaging, and pet data analysis	Analyzed the data	Formal analysis|Visualization	YES
5810347	29178578	All authors	2	reviewed, contributed to and approved the final manuscript	reviewed, contributed to and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5810347	29178578	CNM	2	initiated the study, contributed to the study design and data collection, and was the main investigator responsible for the interpretation of results and drafting of the manuscript	initiated the study, contributed to the study design and data collection, and was the main investigator responsible for the interpretation of results and drafting of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
5810347	29178578	EJB	2	contributed to the study design, data collection and analysis, and drafting of the manuscript	contributed to the study design, data collection and analysis, and drafting of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
5810347	29178578	JAM	2	contributed to the study design and drafting of the manuscript	contributed to the study design and drafting of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5810347	29178578	KF	2	contributed to the study design and led the data collection	contributed to the study design and led the data collection	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources	YES
5810347	29178578	MFC	2	contributed to the data analysis and drafting of the manuscript	contributed to the data analysis and drafting of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6175238	30014503	All	2	members of the vwm research group contributed to identification and inclusion of patients and the acquisition of clinical data	members of the vwm research group contributed to identification and inclusion of patients and the acquisition of clinical data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
6175238	30014503	All authors	2	contributed to data acquisition and design	contributed to data acquisition and design	Conceived and designed the experiments|Performed the experiments	Investigation	YES
6175238	30014503	E.M.C.H.	2	drafted the manuscript and figures	drafted the manuscript and figures	Wrote the paper	Visualization|Writing - Original Draft	YES
6175238	30014503	M.S.v.d.K.	2	contributed to the conception and design of the study|drafted the manuscript and figures	contributed to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6175238	30014503	M.S.v.d.K.	2	contributed to the conception and design of the study|drafted the manuscript and figures	drafted the manuscript and figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5611643	28979288	BJ	2	conceived and designed the research|edited the manuscript	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5611643	28979288	BJ	2	conceived and designed the research|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5611643	28979288	KL	2	conducted dna and rna isolations	conducted dna and rna isolations	Performed the experiments	Investigation	YES
5611643	28979288	TL	2	conceived and designed the research|edited the manuscript	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5611643	28979288	TL	2	conceived and designed the research|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5611643	28979288	XX	2	conducted dna and rna isolations	conducted dna and rna isolations	Performed the experiments	Investigation	YES
5611643	28979288	XZ	2	conducted dna and rna isolations	conducted dna and rna isolations	Performed the experiments	Investigation	YES
5611643	28979288	YG	2	provided figures and tables	provided figures and tables	-	Visualization	YES
5611643	28979288	YX	2	conceived and designed the research|wrote the manuscript	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5611643	28979288	YX	2	conceived and designed the research|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5611643	28979288	ZW	2	provided figures and tables	provided figures and tables	-	Visualization	YES
1762388	17183718	AR	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1762388	17183718	BP	PLoS5	Analyzed the data|Analyzed the data|Wrote the paper|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762388	17183718	BP	PLoS5	Analyzed the data|Analyzed the data|Wrote the paper|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762388	17183718	BP	PLoS5	Analyzed the data|Analyzed the data|Wrote the paper|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762388	17183718	BP	PLoS5	Analyzed the data|Analyzed the data|Wrote the paper|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762388	17183718	EK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1762388	17183718	EZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1762388	17183718	GP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1762388	17183718	NG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1762388	17183718	PL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1762388	17183718	RB	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762388	17183718	SA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762388	17183718	SA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762388	17183718	SA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762388	17183718	SR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762388	17183718	SR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762388	17183718	SR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762388	17183718	SR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762388	17183718	TL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
3377914	22214246	FJ	2	participated in the design of the study|participated in the data analysis and in the writing of the manuscript	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
3377914	22214246	FJ	2	participated in the design of the study|participated in the data analysis and in the writing of the manuscript	participated in the data analysis and in the writing of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3377914	22214246	GD	2	participated in the design of the study	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
3377914	22214246	MH	2	developed the reconstruction algorithm|participated in the data analysis and in the writing of the manuscript	developed the reconstruction algorithm	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
3377914	22214246	MH	2	developed the reconstruction algorithm|participated in the data analysis and in the writing of the manuscript	participated in the data analysis and in the writing of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3377914	22214246	SP	2	participated in the data analysis and in the writing of the manuscript	participated in the data analysis and in the writing of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3377914	22214246	SW	2	conceived the method|participated in the design of the study|developed the reconstruction algorithm|participated in the data analysis and in the writing of the manuscript	conceived the method	Conceived and designed the experiments|Performed the experiments	Conceptualization	YES
3377914	22214246	SW	2	conceived the method|participated in the design of the study|developed the reconstruction algorithm|participated in the data analysis and in the writing of the manuscript	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
3377914	22214246	SW	2	conceived the method|participated in the design of the study|developed the reconstruction algorithm|participated in the data analysis and in the writing of the manuscript	developed the reconstruction algorithm	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
3377914	22214246	SW	2	conceived the method|participated in the design of the study|developed the reconstruction algorithm|participated in the data analysis and in the writing of the manuscript	participated in the data analysis and in the writing of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4409053	25909857	EJ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4409053	25909857	EJ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4409053	25909857	EJ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409053	25909857	JYC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409053	25909857	JYC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409053	25909857	JYC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409053	25909857	JYC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409053	25909857	Jienny Lee	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409053	25909857	Jongsung Lee	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409053	25909857	Jongsung Lee	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409053	25909857	Jongsung Lee	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409053	25909857	KJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409053	25909857	KJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409053	25909857	KJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409053	25909857	KJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409053	25909857	MK	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4409053	25909857	MK	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4409053	25909857	MK	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409053	25909857	SJ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409053	25909857	SWS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409053	25909857	YJS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409053	25909857	YJS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409053	25909857	YJS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5810348	29236362	AJR	PLoS52	conceptualized and designed the study|acquired the data|analysed the data|wrote the paper|reviewed and edited the manuscript	conceptualized and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5810348	29236362	AJR	PLoS52	conceptualized and designed the study|acquired the data|analysed the data|wrote the paper|reviewed and edited the manuscript	acquired the data	Performed the experiments	Investigation	YES
5810348	29236362	AJR	PLoS52	conceptualized and designed the study|acquired the data|analysed the data|wrote the paper|reviewed and edited the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
5810348	29236362	AJR	PLoS52	conceptualized and designed the study|acquired the data|analysed the data|wrote the paper|reviewed and edited the manuscript	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5810348	29236362	AJR	PLoS52	conceptualized and designed the study|acquired the data|analysed the data|wrote the paper|reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5810348	29236362	CRC	PLoS52	conceptualized and designed the study|reviewed and edited the manuscript	conceptualized and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5810348	29236362	CRC	PLoS52	conceptualized and designed the study|reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5810348	29236362	EA	PLoS52	conceptualized and designed the study|reviewed and edited the manuscript	conceptualized and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5810348	29236362	EA	PLoS52	conceptualized and designed the study|reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5810348	29236362	EAB	PLoS52	conceptualized and designed the study|reviewed and edited the manuscript	conceptualized and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5810348	29236362	EAB	PLoS52	conceptualized and designed the study|reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5810348	29236362	EW	PLoS52	acquired the data|reviewed and edited the manuscript	acquired the data	Performed the experiments	Investigation	YES
5810348	29236362	EW	PLoS52	acquired the data|reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5810348	29236362	GO	PLoS52	acquired the data|reviewed and edited the manuscript	acquired the data	Performed the experiments	Investigation	YES
5810348	29236362	GO	PLoS52	acquired the data|reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5810348	29236362	JB	PLoS52	analysed the data|reviewed and edited the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
5810348	29236362	JB	PLoS52	analysed the data|reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5810348	29236362	JMT	PLoS52	conceptualized and designed the study|analysed the data|wrote the paper|reviewed and edited the manuscript	conceptualized and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5810348	29236362	JMT	PLoS52	conceptualized and designed the study|analysed the data|wrote the paper|reviewed and edited the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
5810348	29236362	JMT	PLoS52	conceptualized and designed the study|analysed the data|wrote the paper|reviewed and edited the manuscript	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5810348	29236362	JMT	PLoS52	conceptualized and designed the study|analysed the data|wrote the paper|reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5810348	29236362	PO	PLoS52	conceptualized and designed the study|reviewed and edited the manuscript	conceptualized and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5810348	29236362	PO	PLoS52	conceptualized and designed the study|reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5810348	29236362	ZAK	PLoS52	conceptualized and designed the study|reviewed and edited the manuscript	conceptualized and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5810348	29236362	ZAK	PLoS52	conceptualized and designed the study|reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5418865	28472935	ALC	2	performed microarray experiments, analyzed the data and did qpcr analysis	performed microarray experiments, analyzed the data and did qpcr analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5418865	28472935	CR	2	performed microarray experiments, analyzed the data and did qpcr analysis	performed microarray experiments, analyzed the data and did qpcr analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5418865	28472935	CW	2	helped draft the manuscript	helped draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5418865	28472935	EC	2	helped draft the manuscript	helped draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5418865	28472935	IN	2	helped draft the manuscript	helped draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5418865	28472935	JCG	2	helped draft the manuscript	helped draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5418865	28472935	JG	2	helped draft the manuscript	helped draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5418865	28472935	JM	2	performed microarray experiments, analyzed the data and did qpcr analysis	performed microarray experiments, analyzed the data and did qpcr analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5418865	28472935	MB	2	did the cell cultures, rna extraction, western blot analysis, analyzed the data and wrote the manuscript	did the cell cultures, rna extraction, western blot analysis, analyzed the data and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5418865	28472935	PYR	2	helped draft the manuscript	helped draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5418865	28472935	VL	2	performed microarray experiments, analyzed the data and did qpcr analysis	performed microarray experiments, analyzed the data and did qpcr analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
1762389	17183668	DS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762389	17183668	DS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762389	17183668	DS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762389	17183668	DS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762389	17183668	HI	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1762389	17183668	SG	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762389	17183668	SG	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5810349	29436776	All authors	2	contributed equally to the writing of this manuscript and approved the final version	contributed equally to the writing of this manuscript and approved the final version	Wrote the paper	Writing - Original Draft	YES
5611679	28979279	AL	2	participated in the design of the study and interpretation	participated in the design of the study and interpretation	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5611679	28979279	AO	2	participated in the design of the study and interpretation	participated in the design of the study and interpretation	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5611679	28979279	CM	2	conducted experiments	conducted experiments	Performed the experiments	Investigation	YES
5611679	28979279	DD	2	conducted experiments|wrote the first draft of the manuscript, to which all authors contributed	conducted experiments	Performed the experiments	Investigation	YES
5611679	28979279	DD	2	conducted experiments|wrote the first draft of the manuscript, to which all authors contributed	wrote the first draft of the manuscript, to which all authors contributed	Wrote the paper	Writing - Original Draft	YES
5611679	28979279	DG	2	assisted in the supervision of this work	assisted in the supervision of this work	-	Supervision	YES
5611679	28979279	EA	2	conducted experiments	conducted experiments	Performed the experiments	Investigation	YES
5611679	28979279	FL	2	achieved bioinformatics analyses	achieved bioinformatics analyses	Analyzed the data	Formal analysis	YES
5611679	28979279	GG	2	conducted experiments|conceived, supervised and coordinated the work|wrote the first draft of the manuscript, to which all authors contributed	conducted experiments	Performed the experiments	Investigation	YES
5611679	28979279	GG	2	conducted experiments|conceived, supervised and coordinated the work|wrote the first draft of the manuscript, to which all authors contributed	conceived, supervised and coordinated the work	Conceived and designed the experiments	Conceptualization|Project administration|Supervision	YES
5611679	28979279	GG	2	conducted experiments|conceived, supervised and coordinated the work|wrote the first draft of the manuscript, to which all authors contributed	wrote the first draft of the manuscript, to which all authors contributed	Wrote the paper	Writing - Original Draft	YES
5611679	28979279	JC	2	assisted in the supervision of this work	assisted in the supervision of this work	-	Supervision	YES
5611679	28979279	MCl	2	participated in the design of the study and interpretation	participated in the design of the study and interpretation	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5611679	28979279	MCo	2	assisted in the supervision of this work	assisted in the supervision of this work	-	Supervision	YES
5611679	28979279	NG-G	2	assisted in the supervision of this work	assisted in the supervision of this work	-	Supervision	YES
5611679	28979279	NP	2	participated in the design of the study and interpretation	participated in the design of the study and interpretation	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5611679	28979279	OP	2	participated in the design of the study and interpretation	participated in the design of the study and interpretation	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5611679	28979279	SB	2	participated in the design of the study and interpretation|assisted in the supervision of this work	participated in the design of the study and interpretation	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5611679	28979279	SB	2	participated in the design of the study and interpretation|assisted in the supervision of this work	assisted in the supervision of this work	-	Supervision	YES
5611679	28979279	SC	2	assisted in the supervision of this work	assisted in the supervision of this work	-	Supervision	YES
5611679	28979279	TDdB	2	achieved bioinformatics analyses	achieved bioinformatics analyses	Analyzed the data	Formal analysis	YES
5611679	28979279	VC	2	participated in the design of the study and interpretation	participated in the design of the study and interpretation	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
6175482	30246904	All the authors	2	reviewed, revised, and approved the final manuscript	reviewed, revised, and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6175482	30246904	B.B.	2	were responsible for designing and performing the experiments|were responsible for drafting the manuscript and figures	were responsible for designing and performing the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6175482	30246904	B.B.	2	were responsible for designing and performing the experiments|were responsible for drafting the manuscript and figures	were responsible for drafting the manuscript and figures	Wrote the paper	Visualization|Writing - Original Draft	YES
6175482	30246904	D.H.	2	were responsible for designing and performing the experiments|were responsible for acquiring and analyzing the data|were responsible for drafting the manuscript and figures	were responsible for designing and performing the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6175482	30246904	D.H.	2	were responsible for designing and performing the experiments|were responsible for acquiring and analyzing the data|were responsible for drafting the manuscript and figures	were responsible for acquiring and analyzing the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6175482	30246904	D.H.	2	were responsible for designing and performing the experiments|were responsible for acquiring and analyzing the data|were responsible for drafting the manuscript and figures	were responsible for drafting the manuscript and figures	Wrote the paper	Visualization|Writing - Original Draft	YES
6175482	30246904	D.P.	2	were responsible for designing and performing the experiments	were responsible for designing and performing the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6175482	30246904	H.Z.	2	were responsible for designing and performing the experiments|were responsible for acquiring and analyzing the data	were responsible for designing and performing the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6175482	30246904	H.Z.	2	were responsible for designing and performing the experiments|were responsible for acquiring and analyzing the data	were responsible for acquiring and analyzing the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6175482	30246904	J.X.	2	were responsible for designing and performing the experiments|were responsible for acquiring and analyzing the data	were responsible for designing and performing the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6175482	30246904	J.X.	2	were responsible for designing and performing the experiments|were responsible for acquiring and analyzing the data	were responsible for acquiring and analyzing the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6175482	30246904	M.W.	2	were responsible for designing and performing the experiments	were responsible for designing and performing the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6175482	30246904	M.X.	2	were responsible for designing and performing the experiments	were responsible for designing and performing the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6175482	30246904	M.Z.	2	were responsible for designing and performing the experiments|were responsible for acquiring and analyzing the data|were responsible for drafting the manuscript and figures	were responsible for designing and performing the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6175482	30246904	M.Z.	2	were responsible for designing and performing the experiments|were responsible for acquiring and analyzing the data|were responsible for drafting the manuscript and figures	were responsible for acquiring and analyzing the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6175482	30246904	M.Z.	2	were responsible for designing and performing the experiments|were responsible for acquiring and analyzing the data|were responsible for drafting the manuscript and figures	were responsible for drafting the manuscript and figures	Wrote the paper	Visualization|Writing - Original Draft	YES
6175482	30246904	W.W.	2	were responsible for designing and performing the experiments|were responsible for drafting the manuscript and figures	were responsible for designing and performing the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6175482	30246904	W.W.	2	were responsible for designing and performing the experiments|were responsible for drafting the manuscript and figures	were responsible for drafting the manuscript and figures	Wrote the paper	Visualization|Writing - Original Draft	YES
6175482	30246904	X.L.	2	were responsible for designing and performing the experiments	were responsible for designing and performing the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6175482	30246904	X.Z.	2	were responsible for designing and performing the experiments	were responsible for designing and performing the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3713366	23935423	Junzeng Xu	2	performed the data analysis and wrote the paper	performed the data analysis and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3713366	23935423	Qi Wei	2	contributed to the field experiment and laboratory assay	contributed to the field experiment and laboratory assay	Performed the experiments	Investigation	YES
3713366	23935423	Shihong Yang	2	contributed significantly to data analysis and paper preparation	contributed significantly to data analysis and paper preparation	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
3713366	23935423	Shizhang Peng	2	is the corresponding author, conceived, and designed the experiments	is the corresponding author, conceived, and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
3713366	23935423	Xiaoli Gao	2	contributed to the field experiment and laboratory assay	contributed to the field experiment and laboratory assay	Performed the experiments	Investigation	YES
4409056	25909780	AB	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409056	25909780	AL	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4409056	25909780	AL	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409056	25909780	BF	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4409056	25909780	BF	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409056	25909780	BH	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409056	25909780	D. Daniels	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409056	25909780	D. Dranow	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4409056	25909780	D. Dranow	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409056	25909780	DF	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4409056	25909780	DF	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409056	25909780	EW	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4409056	25909780	EW	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409056	25909780	GW	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409056	25909780	GX	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4409056	25909780	GX	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409056	25909780	JA	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4409056	25909780	JA	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409056	25909780	JF	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4409056	25909780	JF	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409056	25909780	JVD	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409056	25909780	KA	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4409056	25909780	KA	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409056	25909780	MCC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409056	25909780	MCC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409056	25909780	MCC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409056	25909780	MSW	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409056	25909780	MSW	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409056	25909780	TG	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409056	25909780	ZN	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4409056	25909780	ZN	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
3395842	22297096	TB	2	guided the data analysis and statistics	guided the data analysis and statistics	Analyzed the data	Formal analysis|Supervision	YES
5420106	28476147	CS	2	performed the statistical analysis|performed the cis-motifs analysis|helped to draft the manuscript	performed the statistical analysis	Analyzed the data	Formal analysis	YES
5420106	28476147	CS	2	performed the statistical analysis|performed the cis-motifs analysis|helped to draft the manuscript	performed the cis-motifs analysis	Performed the experiments	Investigation	YES
5420106	28476147	CS	2	performed the statistical analysis|performed the cis-motifs analysis|helped to draft the manuscript	helped to draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5420106	28476147	CY	2	drafted the manuscript|conceived of the study, and participated in its design	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5420106	28476147	CY	2	drafted the manuscript|conceived of the study, and participated in its design	conceived of the study, and participated in its design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5420106	28476147	HL	2	carried out the molecular studies	carried out the molecular studies	Performed the experiments	Investigation	YES
5420106	28476147	JZ	2	took care the plants	took care the plants	Performed the experiments	Investigation	YES
5420106	28476147	KL	2	carried out the molecular studies|drafted the manuscript|conceived of the study, and participated in its design|acquired of funding	carried out the molecular studies	Performed the experiments	Investigation	YES
5420106	28476147	KL	2	carried out the molecular studies|drafted the manuscript|conceived of the study, and participated in its design|acquired of funding	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5420106	28476147	KL	2	carried out the molecular studies|drafted the manuscript|conceived of the study, and participated in its design|acquired of funding	conceived of the study, and participated in its design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5420106	28476147	KL	2	carried out the molecular studies|drafted the manuscript|conceived of the study, and participated in its design|acquired of funding	acquired of funding	-	Funding acquisition	YES
5420106	28476147	SF	2	carried out the molecular studies	carried out the molecular studies	Performed the experiments	Investigation	YES
5420106	28476147	SZ	2	carried out the molecular studies|performed the statistical analysis	carried out the molecular studies	Performed the experiments	Investigation	YES
5420106	28476147	SZ	2	carried out the molecular studies|performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
5817972	29457868	AB	2	supported study and data collection tool design and data analysis	supported study and data collection tool design and data analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5817972	29457868	All authors	2	contributed to drafting and finalizing the manuscript	contributed to drafting and finalizing the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5817972	29457868	HR	2	oversaw the project as principal investigator	oversaw the project as principal investigator	Conceived and designed the experiments	Conceptualization|Funding acquisition|Supervision	YES
5817972	29457868	JM	2	facilitated data collection and analysis	facilitated data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5817972	29457868	NM	2	supported data collection	supported data collection	Performed the experiments	Investigation	YES
5817972	29457868	RE	2	designed the study and data collection tools, participated in data collection, analysed the data and drafted the paper	designed the study and data collection tools, participated in data collection, analysed the data and drafted the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
1762390	17183665	AC	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762390	17183665	AC	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762390	17183665	AN	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762390	17183665	HT	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762390	17183665	KI	PLoS5	Provided advice about technical issues in using zebrafish	Provided advice about technical issues in using zebrafish	-	-	NO
1762390	17183665	NK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762390	17183665	NK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762390	17183665	NK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762390	17183665	TU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762390	17183665	TU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762390	17183665	TU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762390	17183665	TU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762390	17183665	YN	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5611683	28979277	AA	2	conceived and conducted the trials|were primarily responsible for writing the manuscript	conceived and conducted the trials	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5611683	28979277	AA	2	conceived and conducted the trials|were primarily responsible for writing the manuscript	were primarily responsible for writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5611683	28979277	AR	2	assisted in the data collection|were primarily responsible for writing the manuscript	assisted in the data collection	Performed the experiments	Investigation	YES
5611683	28979277	AR	2	assisted in the data collection|were primarily responsible for writing the manuscript	were primarily responsible for writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5611683	28979277	CG	2	conceived and conducted the trials|were primarily responsible for writing the manuscript	conceived and conducted the trials	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5611683	28979277	CG	2	conceived and conducted the trials|were primarily responsible for writing the manuscript	were primarily responsible for writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5611683	28979277	RV	2	conceived and conducted the trials	conceived and conducted the trials	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
4409059	25909508	CL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409059	25909508	CL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409059	25909508	CL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409059	25909508	CL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409059	25909508	HS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409059	25909508	HS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409059	25909508	HS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409059	25909508	HS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409059	25909508	JL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409059	25909508	JL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409059	25909508	JL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409059	25909508	JL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409059	25909508	MM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4409059	25909508	MM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409059	25909508	PP	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409059	25909508	PP	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409059	25909508	PP	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409059	25909508	PP	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3405466	22651703	AB	2	jointly performed protein extraction and western blot analysis	jointly performed protein extraction and western blot analysis	Performed the experiments	Investigation	YES
3405466	22651703	FDG	2	uptake studies, immunostaining and drafted the manuscript	uptake studies, immunostaining and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3405466	22651703	FDG-PET	2	imaging and analysis	imaging and analysis	Analyzed the data	Visualization	YES
3405466	22651703	FS	2	provided the a375 r1 and r3 vemurafenib-resistant cell lines, and provided manuscript input	provided the a375 r1 and r3 vemurafenib-resistant cell lines, and provided manuscript input	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
3405466	22651703	KH	2	conceived of the study and helped draft the manuscript	conceived of the study and helped draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
3405466	22651703	NvB	2	conceived of the study and helped draft the manuscript	conceived of the study and helped draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
3405466	22651703	SW	2	conceived of the study and helped draft the manuscript	conceived of the study and helped draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
3405466	22651703	TD	2	jointly performed protein extraction and western blot analysis	jointly performed protein extraction and western blot analysis	Performed the experiments	Investigation	YES
6220799	30155979	C.B.	1	Data acquisition and analysis	Data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6220799	30155979	G.D.-B.	1	Data acquisition and analysis	Data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6220799	30155979	G.G.	1	Data acquisition and analysis	Data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6220799	30155979	H.G.	1	Study concept and design|Data acquisition and analysis	Study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6220799	30155979	H.G.	1	Study concept and design|Data acquisition and analysis	Data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6220799	30155979	J.S.W.	1	Study concept and design|Data acquisition and analysis	Study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6220799	30155979	J.S.W.	1	Study concept and design|Data acquisition and analysis	Data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6220799	30155979	L.K.	1	Study concept and design|Data acquisition and analysis	Study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6220799	30155979	L.K.	1	Study concept and design|Data acquisition and analysis	Data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6220799	30155979	P.C.	1	Study concept and design|Data acquisition and analysis	Study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6220799	30155979	P.C.	1	Study concept and design|Data acquisition and analysis	Data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6220799	30155979	P.V.	1	Data acquisition and analysis	Data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6220799	30155979	S.B.	1	Data acquisition and analysis	Data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6220799	30155979	S.L.H.	1	Study concept and design|Data acquisition and analysis	Study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6220799	30155979	S.L.H.	1	Study concept and design|Data acquisition and analysis	Data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6220799	30155979	X.M.	1	Study concept and design|Data acquisition and analysis	Study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6220799	30155979	X.M.	1	Study concept and design|Data acquisition and analysis	Data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
1762391	17205141	AC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Designed simulations, wrote the modeling code	Analyzed the data	Analyzed the data	Formal analysis	YES
1762391	17205141	AC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Designed simulations, wrote the modeling code	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762391	17205141	AC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Designed simulations, wrote the modeling code	Designed simulations, wrote the modeling code	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Formal analysis|Methodology|Software|Writing - Original Draft	YES
1762391	17205141	GP	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Designed simulations, wrote the modeling code, performed the simulations, and made the figures	Performed the experiments	Performed the experiments	Investigation	YES
1762391	17205141	GP	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Designed simulations, wrote the modeling code, performed the simulations, and made the figures	Analyzed the data	Analyzed the data	Formal analysis	YES
1762391	17205141	GP	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Designed simulations, wrote the modeling code, performed the simulations, and made the figures	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762391	17205141	GP	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Designed simulations, wrote the modeling code, performed the simulations, and made the figures	Designed simulations, wrote the modeling code, performed the simulations, and made the figures	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Formal analysis|Investigation|Methodology|Software|Visualization|Writing - Original Draft	YES
1762391	17205141	MM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Conceived the project, designed simulations	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762391	17205141	MM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Conceived the project, designed simulations	Analyzed the data	Analyzed the data	Formal analysis	YES
1762391	17205141	MM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Conceived the project, designed simulations	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762391	17205141	MM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Conceived the project, designed simulations	Conceived the project, designed simulations	Conceived and designed the experiments	Conceptualization|Formal analysis|Methodology	YES
5611792	28979276	AH	2	agreed before submissions	agreed before submissions	-	-	NO
5611792	28979276	MI	2	agreed before submissions	agreed before submissions	-	-	NO
5611792	28979276	SA	2	modified the original experiments and implemented 2011 and 2012 at the same place|agreed before submissions	modified the original experiments and implemented 2011 and 2012 at the same place	Performed the experiments	Investigation	YES
5611792	28979276	SA	2	modified the original experiments and implemented 2011 and 2012 at the same place|agreed before submissions	agreed before submissions	-	-	NO
5611792	28979276	SK	2	agreed before submissions	agreed before submissions	-	-	NO
5829581	29489059	All of the authors	2	contributed to preparation of the manuscript	contributed to preparation of the manuscript	Wrote the paper	Writing - Original Draft	YES
5829581	29489059	Eshleman Conceived	2	of the study, drafted the manuscript	of the study, drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5420122	28477619	GMS	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5420122	28477619	JEA	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5420122	28477619	KMM	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5420122	28477619	KMM	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5420122	28477619	KMR	PLoS52	conceived and designed the experiments|analyzed the data|drafted the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5420122	28477619	KMR	PLoS52	conceived and designed the experiments|analyzed the data|drafted the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5420122	28477619	KMR	PLoS52	conceived and designed the experiments|analyzed the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5420122	28477619	NEB	PLoS52	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5420122	28477619	SGV	PLoS52	conceived and designed the experiments|performed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5420122	28477619	SGV	PLoS52	conceived and designed the experiments|performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
3407795	22682002	AT	2	was actively engaged in peptide synthesis, radiolabeling, and biological evaluation and assisted in writing the manuscript	was actively engaged in peptide synthesis, radiolabeling, and biological evaluation and assisted in writing the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3407795	22682002	BAN	2	designed the overall study and supervised radiochemical work, as well as the generation and final editing of this ms	designed the overall study and supervised radiochemical work, as well as the generation and final editing of this ms	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Review & Editing	YES
3407795	22682002	EPK	2	edited the ms	edited the ms	Wrote the paper	Writing - Review & Editing	YES
3407795	22682002	JCR	2	edited the ms	edited the ms	Wrote the paper	Writing - Review & Editing	YES
3407795	22682002	MdJ	2	edited the ms	edited the ms	Wrote the paper	Writing - Review & Editing	YES
3407795	22682002	PC	2	supervised peptide synthesis and participated in the design of analogs	supervised peptide synthesis and participated in the design of analogs	Conceived and designed the experiments|Performed the experiments	Investigation|Supervision	YES
3407795	22682002	TM	2	performed animal studies and drafted most parts of the ms	performed animal studies and drafted most parts of the ms	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4409060	25910253	JBD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409060	25910253	JBD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409060	25910253	JBD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409060	25910253	JBD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409060	25910253	JBD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409060	25910253	JPC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409060	25910253	JPC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409060	25910253	JPC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409060	25910253	JPC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5832948	29498234	All authors	2	contributed to the writing of the manuscript and reviewed and approved the final version	contributed to the writing of the manuscript and reviewed and approved the final version	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5832948	29498234	PDG	2	advised on the interpretation of the analysis	advised on the interpretation of the analysis	Analyzed the data	Formal analysis	YES
5832948	29498234	RO	2	advised on the interpretation of the analysis	advised on the interpretation of the analysis	Analyzed the data	Formal analysis	YES
5832948	29498234	SJA	2	conceived the study and developed the methods and analysis|wrote the first draft of the paper	conceived the study and developed the methods and analysis	Conceived and designed the experiments|Performed the experiments	Conceptualization|Methodology	YES
5832948	29498234	SJA	2	conceived the study and developed the methods and analysis|wrote the first draft of the paper	wrote the first draft of the paper	Wrote the paper	Writing - Original Draft	YES
5832948	29498234	TBH	2	conceived the study and developed the methods and analysis	conceived the study and developed the methods and analysis	Conceived and designed the experiments|Performed the experiments	Conceptualization|Methodology	YES
5613130	28983303	BA	1	Concept development, experimental planning, revision of initial draft	Concept development, experimental planning, revision of initial draft	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5613130	28983303	DT	1	Concept development, experimental planning, revision of initial draft	Concept development, experimental planning, revision of initial draft	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5613130	28983303	MB	1	Concept development, experimental planning, revision of initial draft	Concept development, experimental planning, revision of initial draft	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5613130	28983303	MS	1	Experimental execution, data collection, analysis, and initial writing	Experimental execution, data collection, analysis, and initial writing	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation	YES
5613130	28983303	UN	1	Experimental execution, data collection, analysis, and initial writing	Experimental execution, data collection, analysis, and initial writing	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation	YES
1762392	17183669	KR	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1762392	17183669	MF	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762392	17183669	MF	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762392	17183669	MF	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762392	17183669	PW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762392	17183669	PW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762392	17183669	PW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762392	17183669	RB	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762392	17183669	RB	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762392	17183669	SR	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762392	17183669	SS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762392	17183669	SS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1762392	17183669	SS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762392	17183669	ST	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
3413527	22626255	AV	2	has made substantial contributions to conception and design, acquisition, analysis and interpretation of data and drafted the manuscript	has made substantial contributions to conception and design, acquisition, analysis and interpretation of data and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Resources|Writing - Original Draft	YES
3413527	22626255	DM	2	assisted in the design of the imaging protocol and data analysis	assisted in the design of the imaging protocol and data analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology|Visualization	YES
3413527	22626255	MS	2	conceived the study, participated in its interpretation and has critically revised the manuscript	conceived the study, participated in its interpretation and has critically revised the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Review & Editing	YES
3413527	22626255	OS	2	has inspired the question of translation from mice to man and has critically revised the manuscript	has inspired the question of translation from mice to man and has critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
3413527	22626255	SH	2	participated in the design and interpretation of the study and has critically revised the manuscript	participated in the design and interpretation of the study and has critically revised the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
5420399	28477620	All authors	2	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5420399	28477620	BW	2	performed the procedures, analyzed all the data, and wrote the manuscript	performed the procedures, analyzed all the data, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5420399	28477620	DMW	2	performed the procedures, analyzed all the data, and wrote the manuscript	performed the procedures, analyzed all the data, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5420399	28477620	JC	2	helped with sampling during the slaughter trial and provided the trait data	helped with sampling during the slaughter trial and provided the trait data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5420399	28477620	JSW	2	helped with sampling during the slaughter trial and provided the trait data	helped with sampling during the slaughter trial and provided the trait data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5420399	28477620	JXL	2	conceived and designed the study and methods, revised the manuscript, and offered valuable suggestions on the manuscript and methods	conceived and designed the study and methods, revised the manuscript, and offered valuable suggestions on the manuscript and methods	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
5420399	28477620	LLG	2	conceived and designed the study and methods, revised the manuscript, and offered valuable suggestions on the manuscript and methods	conceived and designed the study and methods, revised the manuscript, and offered valuable suggestions on the manuscript and methods	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
5420399	28477620	ML	2	helped with sampling during the slaughter trial and provided the trait data	helped with sampling during the slaughter trial and provided the trait data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5420399	28477620	XBH	2	helped with sampling during the slaughter trial and provided the trait data	helped with sampling during the slaughter trial and provided the trait data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5420399	28477620	XHW	2	helped with sampling during the slaughter trial and provided the trait data	helped with sampling during the slaughter trial and provided the trait data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
6221157	30155909	F.R.	2	contributed to conception and design of the study	contributed to conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6221157	30155909	F.V.-K.	2	contributed to conception and design of the study	contributed to conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6221157	30155909	M.J.P.	2	contributed to conception and design of the study	contributed to conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6221157	30155909	P.L.	2	contributed to conception and design of the study	contributed to conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6221157	30155909	V.G.	2	contributed to conception and design of the study	contributed to conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6221157	30155909	all authors	2	contributed to acquisition and analysis of data|contributed to drafting the text and preparing the figures	contributed to acquisition and analysis of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
6221157	30155909	all authors	2	contributed to acquisition and analysis of data|contributed to drafting the text and preparing the figures	contributed to drafting the text and preparing the figures	Wrote the paper	Visualization|Writing - Original Draft	YES
4409061	25909191	CMK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409061	25909191	CMK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409061	25909191	CMK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409061	25909191	JSB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409061	25909191	JSB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409061	25909191	JSB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409061	25909191	MJD	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409061	25909191	MJD	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409061	25909191	MJD	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409061	25909191	NJ	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409061	25909191	NJ	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409061	25909191	NJ	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409061	25909191	SGP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409061	25909191	SGP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409061	25909191	SGP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409061	25909191	SGP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409061	25909191	SGP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5835841	29504269	AFP	2	collaborated on project design, sampling and reagent distribution logistics	collaborated on project design, sampling and reagent distribution logistics	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Project administration	YES
5835841	29504269	AMSC	2	worked on sample collection and genotyping tests	worked on sample collection and genotyping tests	Performed the experiments	Investigation	YES
5835841	29504269	AOPE	2	worked on sample collection and genotyping tests	worked on sample collection and genotyping tests	Performed the experiments	Investigation	YES
5835841	29504269	AT	2	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5835841	29504269	AWA	2	worked on sample collection and genotyping tests	worked on sample collection and genotyping tests	Performed the experiments	Investigation	YES
5835841	29504269	CCC	2	executed statistical analysis	executed statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5835841	29504269	CMC	2	worked on sample collection and genotyping tests	worked on sample collection and genotyping tests	Performed the experiments	Investigation	YES
5835841	29504269	CRBA	2	worked on sample collection and genotyping tests	worked on sample collection and genotyping tests	Performed the experiments	Investigation	YES
5835841	29504269	FM	2	collaborated on project design, sampling and reagent distribution logistics	collaborated on project design, sampling and reagent distribution logistics	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Project administration	YES
5835841	29504269	FMT	2	worked on sample collection and genotyping tests	worked on sample collection and genotyping tests	Performed the experiments	Investigation	YES
5835841	29504269	GISLL	2	worked on sample collection and genotyping tests	worked on sample collection and genotyping tests	Performed the experiments	Investigation	YES
5835841	29504269	HHCW	2	worked on sample collection and genotyping tests	worked on sample collection and genotyping tests	Performed the experiments	Investigation	YES
5835841	29504269	HTK	2	worked on sample collection and genotyping tests	worked on sample collection and genotyping tests	Performed the experiments	Investigation	YES
5835841	29504269	ICMO	2	worked on sample collection and genotyping tests	worked on sample collection and genotyping tests	Performed the experiments	Investigation	YES
5835841	29504269	JCCF	2	worked on sample collection and genotyping tests	worked on sample collection and genotyping tests	Performed the experiments	Investigation	YES
5835841	29504269	LEP	2	worked on sample collection and genotyping tests	worked on sample collection and genotyping tests	Performed the experiments	Investigation	YES
5835841	29504269	LTB	2	worked on sample collection and genotyping tests	worked on sample collection and genotyping tests	Performed the experiments	Investigation	YES
5835841	29504269	MBA	2	generated and analysed data	generated and analysed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5835841	29504269	MF	2	collaborated on project design, sampling and reagent distribution logistics	collaborated on project design, sampling and reagent distribution logistics	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Project administration	YES
5835841	29504269	MIMCP	2	worked on sample collection and genotyping tests	worked on sample collection and genotyping tests	Performed the experiments	Investigation	YES
5835841	29504269	MR	2	worked on sample collection and genotyping tests	worked on sample collection and genotyping tests	Performed the experiments	Investigation	YES
5835841	29504269	MVCF	2	worked on sample collection and genotyping tests	worked on sample collection and genotyping tests	Performed the experiments	Investigation	YES
5835841	29504269	NMCV	2	analysed the data and wrote the article	analysed the data and wrote the article	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5835841	29504269	RBLF	2	organized sampling and reagent distribution logistics and proofread the article	organized sampling and reagent distribution logistics and proofread the article	Performed the experiments	Investigation|Project administration	YES
5835841	29504269	RSD	2	worked on sample collection and genotyping tests	worked on sample collection and genotyping tests	Performed the experiments	Investigation	YES
5835841	29504269	SBF	2	worked on sample collection and genotyping tests|worked on sample collection and genotyping tests	worked on sample collection and genotyping tests	Performed the experiments	Investigation	YES
5835841	29504269	SBF	2	worked on sample collection and genotyping tests|worked on sample collection and genotyping tests	worked on sample collection and genotyping tests	Performed the experiments	Investigation	YES
5835841	29504269	STSL	2	worked on sample collection and genotyping tests	worked on sample collection and genotyping tests	Performed the experiments	Investigation	YES
5613134	28983306	All authors	2	have read and approved the manuscript	have read and approved the manuscript	-	-	NO
5613134	28983306	BM	2	designed the study|performed the data analyses|drafted the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5613134	28983306	BM	2	designed the study|performed the data analyses|drafted the manuscript	performed the data analyses	Analyzed the data	Formal analysis	YES
5613134	28983306	BM	2	designed the study|performed the data analyses|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5613134	28983306	EB	2	provided genetic resources and phenotypic data	provided genetic resources and phenotypic data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5613134	28983306	FB	2	participated in the data analyses|drafted the manuscript	participated in the data analyses	Analyzed the data	Formal analysis	YES
5613134	28983306	FB	2	participated in the data analyses|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5613134	28983306	FV	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5613134	28983306	GM	2	provided genetic resources and phenotypic data	provided genetic resources and phenotypic data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5613134	28983306	LC	2	provided metabolic data|drafted the manuscript	provided metabolic data	Contributed reagents/materials/analysis tools	Resources	YES
5613134	28983306	LC	2	provided metabolic data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5613134	28983306	LL	2	provided genomic data	provided genomic data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5613134	28983306	MB	2	provided genetic resources and phenotypic data	provided genetic resources and phenotypic data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5613134	28983306	NB	2	provided genetic resources and phenotypic data	provided genetic resources and phenotypic data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5613134	28983306	NL	2	designed the study|drafted the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5613134	28983306	NL	2	designed the study|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5613134	28983306	NP	2	provided genomic data	provided genomic data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5613134	28983306	PP	2	participated in the data analyses	participated in the data analyses	Analyzed the data	Formal analysis	YES
5613134	28983306	PV	2	designed the hybrid factorial design|drafted the manuscript	designed the hybrid factorial design	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5613134	28983306	PV	2	designed the hybrid factorial design|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5613134	28983306	SC	2	provided genomic data	provided genomic data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5613134	28983306	SM	2	provided genomic data	provided genomic data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
3413597	22608186	FJ	2	performed the study design|participated in the paper writing	performed the study design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3413597	22608186	FJ	2	performed the study design|participated in the paper writing	participated in the paper writing	Wrote the paper	-	YES
3413597	22608186	MVE	2	carried out the treatment and follow-up of the patients	carried out the treatment and follow-up of the patients	Performed the experiments	Investigation	YES
3413597	22608186	PG	2	carried out the treatment and follow-up of the patients	carried out the treatment and follow-up of the patients	Performed the experiments	Investigation	YES
3413597	22608186	RL	2	performed the study design|carried out the treatment and follow-up of the patients|participated in the paper writing	performed the study design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3413597	22608186	RL	2	performed the study design|carried out the treatment and follow-up of the patients|participated in the paper writing	carried out the treatment and follow-up of the patients	Performed the experiments	Investigation	YES
3413597	22608186	RL	2	performed the study design|carried out the treatment and follow-up of the patients|participated in the paper writing	participated in the paper writing	Wrote the paper	-	YES
3413597	22608186	SP	2	participated in the paper writing	participated in the paper writing	Wrote the paper	-	YES
3413597	22608186	SW	2	elaborated the hb-dependent dosimetry model and performed the results analysis|participated in the paper writing	elaborated the hb-dependent dosimetry model and performed the results analysis	Performed the experiments	Investigation|Methodology	YES
3413597	22608186	SW	2	elaborated the hb-dependent dosimetry model and performed the results analysis|participated in the paper writing	participated in the paper writing	Wrote the paper	-	YES
1762393	17183705	EC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762393	17183705	EC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762393	17183705	EC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762393	17183705	KZ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762393	17183705	KZ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762393	17183705	KZ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762393	17183705	UR	PLoS5	Contributed reagents/materials/analysis tools|Yai, provided access to study site, habituated animals, provided permits and invaluable background information on the gibbons	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762393	17183705	UR	PLoS5	Contributed reagents/materials/analysis tools|Yai, provided access to study site, habituated animals, provided permits and invaluable background information on the gibbons	Yai, provided access to study site, habituated animals, provided permits and invaluable background information on the gibbons	-	-	NO
6282793	30179273	B.E.	1	Authors involved in the study concept and design were|Authors involved in the data acquisition and analysis were|Authors involved in drafting the text and figures were	Authors involved in the study concept and design were	Conceived and designed the experiments	Conceptualization|Methodology	YES
6282793	30179273	B.E.	1	Authors involved in the study concept and design were|Authors involved in the data acquisition and analysis were|Authors involved in drafting the text and figures were	Authors involved in the data acquisition and analysis were	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6282793	30179273	B.E.	1	Authors involved in the study concept and design were|Authors involved in the data acquisition and analysis were|Authors involved in drafting the text and figures were	Authors involved in drafting the text and figures were	Wrote the paper	Visualization|Writing - Original Draft	YES
6282793	30179273	C.E.	1	Authors involved in the study concept and design were|Authors involved in the data acquisition and analysis were|Authors involved in drafting the text and figures were	Authors involved in the study concept and design were	Conceived and designed the experiments	Conceptualization|Methodology	YES
6282793	30179273	C.E.	1	Authors involved in the study concept and design were|Authors involved in the data acquisition and analysis were|Authors involved in drafting the text and figures were	Authors involved in the data acquisition and analysis were	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6282793	30179273	C.E.	1	Authors involved in the study concept and design were|Authors involved in the data acquisition and analysis were|Authors involved in drafting the text and figures were	Authors involved in drafting the text and figures were	Wrote the paper	Visualization|Writing - Original Draft	YES
6282793	30179273	I.G.	1	Authors involved in the study concept and design were|Authors involved in drafting the text and figures were	Authors involved in the study concept and design were	Conceived and designed the experiments	Conceptualization|Methodology	YES
6282793	30179273	I.G.	1	Authors involved in the study concept and design were|Authors involved in drafting the text and figures were	Authors involved in drafting the text and figures were	Wrote the paper	Visualization|Writing - Original Draft	YES
6282793	30179273	M.J.	1	Authors involved in the data acquisition and analysis were	Authors involved in the data acquisition and analysis were	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6282793	30179273	N.A.	1	Authors involved in the study concept and design were|Authors involved in drafting the text and figures were	Authors involved in the study concept and design were	Conceived and designed the experiments	Conceptualization|Methodology	YES
6282793	30179273	N.A.	1	Authors involved in the study concept and design were|Authors involved in drafting the text and figures were	Authors involved in drafting the text and figures were	Wrote the paper	Visualization|Writing - Original Draft	YES
6282793	30179273	N.V.	1	Authors involved in the study concept and design were|Authors involved in drafting the text and figures were	Authors involved in the study concept and design were	Conceived and designed the experiments	Conceptualization|Methodology	YES
6282793	30179273	N.V.	1	Authors involved in the study concept and design were|Authors involved in drafting the text and figures were	Authors involved in drafting the text and figures were	Wrote the paper	Visualization|Writing - Original Draft	YES
6282793	30179273	P.V.	1	Authors involved in the data acquisition and analysis were	Authors involved in the data acquisition and analysis were	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6282793	30179273	R.G.	1	Authors involved in the study concept and design were|Authors involved in the data acquisition and analysis were|Authors involved in drafting the text and figures were	Authors involved in the study concept and design were	Conceived and designed the experiments	Conceptualization|Methodology	YES
6282793	30179273	R.G.	1	Authors involved in the study concept and design were|Authors involved in the data acquisition and analysis were|Authors involved in drafting the text and figures were	Authors involved in the data acquisition and analysis were	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6282793	30179273	R.G.	1	Authors involved in the study concept and design were|Authors involved in the data acquisition and analysis were|Authors involved in drafting the text and figures were	Authors involved in drafting the text and figures were	Wrote the paper	Visualization|Writing - Original Draft	YES
6282793	30179273	R.L.	1	Authors involved in the data acquisition and analysis were	Authors involved in the data acquisition and analysis were	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6282793	30179273	S.M.	1	Authors involved in the study concept and design were|Authors involved in the data acquisition and analysis were|Authors involved in drafting the text and figures were	Authors involved in the study concept and design were	Conceived and designed the experiments	Conceptualization|Methodology	YES
6282793	30179273	S.M.	1	Authors involved in the study concept and design were|Authors involved in the data acquisition and analysis were|Authors involved in drafting the text and figures were	Authors involved in the data acquisition and analysis were	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6282793	30179273	S.M.	1	Authors involved in the study concept and design were|Authors involved in the data acquisition and analysis were|Authors involved in drafting the text and figures were	Authors involved in drafting the text and figures were	Wrote the paper	Visualization|Writing - Original Draft	YES
6282793	30179273	T.S.	1	Authors involved in the study concept and design were|Authors involved in drafting the text and figures were	Authors involved in the study concept and design were	Conceived and designed the experiments	Conceptualization|Methodology	YES
6282793	30179273	T.S.	1	Authors involved in the study concept and design were|Authors involved in drafting the text and figures were	Authors involved in drafting the text and figures were	Wrote the paper	Visualization|Writing - Original Draft	YES
6282793	30179273	T.T.	1	Authors involved in the data acquisition and analysis were	Authors involved in the data acquisition and analysis were	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3414741	22824200	AJH	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
3414741	22824200	AR	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
3414741	22824200	HTA	2	designed the study|drafted the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
3414741	22824200	HTA	2	designed the study|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
3414741	22824200	KL	2	carried out the experimental aspects of the study	carried out the experimental aspects of the study	Performed the experiments	Investigation	YES
3414741	22824200	PL	2	designed the study|carried out the experimental aspects of the study|drafted the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
3414741	22824200	PL	2	designed the study|carried out the experimental aspects of the study|drafted the manuscript	carried out the experimental aspects of the study	Performed the experiments	Investigation	YES
3414741	22824200	PL	2	designed the study|carried out the experimental aspects of the study|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5613135	28983304	AX	PLoS5	Contributed materials and analyzed the results	Contributed materials and analyzed the results	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5613135	28983304	CY	PLoS5	Conceived and designed the experiments|Performed the experiments|Performed the bioinformatics analysis|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5613135	28983304	CY	PLoS5	Conceived and designed the experiments|Performed the experiments|Performed the bioinformatics analysis|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
5613135	28983304	CY	PLoS5	Conceived and designed the experiments|Performed the experiments|Performed the bioinformatics analysis|Wrote the paper	Performed the bioinformatics analysis	Performed the experiments	Formal analysis|Investigation	YES
5613135	28983304	CY	PLoS5	Conceived and designed the experiments|Performed the experiments|Performed the bioinformatics analysis|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5613135	28983304	JD	PLoS5	Performed the experiments|Contributed materials and analyzed the results	Performed the experiments	Performed the experiments	Investigation	YES
5613135	28983304	JD	PLoS5	Performed the experiments|Contributed materials and analyzed the results	Contributed materials and analyzed the results	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5613135	28983304	SH	PLoS5	Contributed materials and analyzed the results	Contributed materials and analyzed the results	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5613135	28983304	XL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5420408	28477616	C.C.	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5420408	28477616	H.C.	PLoS52	performed the experiment	performed the experiment	Performed the experiments	Investigation	YES
5420408	28477616	L.S.	PLoS52	designed the research|analyzed the data	designed the research	Conceived and designed the experiments	Methodology	YES
5420408	28477616	L.S.	PLoS52	designed the research|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5420408	28477616	M.Q.S.	PLoS52	performed the experiment|analyzed the data	performed the experiment	Performed the experiments	Investigation	YES
5420408	28477616	M.Q.S.	PLoS52	performed the experiment|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5420408	28477616	W.Y.	PLoS52	designed the research|performed the experiment|analyzed the data	designed the research	Conceived and designed the experiments	Methodology	YES
5420408	28477616	W.Y.	PLoS52	designed the research|performed the experiment|analyzed the data	performed the experiment	Performed the experiments	Investigation	YES
5420408	28477616	W.Y.	PLoS52	designed the research|performed the experiment|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
4409062	25909773	AK	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409062	25909773	ALG	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4409062	25909773	ALG	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409062	25909773	AN	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409062	25909773	AN	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409062	25909773	DMU	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409062	25909773	DMU	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409062	25909773	II	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409062	25909773	JT	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4409062	25909773	JT	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409062	25909773	PKF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409062	25909773	PKF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409062	25909773	PKF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409062	25909773	PKF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409062	25909773	PKF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409062	25909773	TTH	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409062	25909773	TW	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409062	25909773	TW	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4409062	25909773	TW	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409062	25909773	VAF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409062	25909773	VAF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409062	25909773	VAF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409062	25909773	VAF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409062	25909773	VAF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409062	25909773	ZC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409062	25909773	ZC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409062	25909773	ZC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4537738	26301250	Antonella Trombetta	2	contributed equally to this work	contributed equally to this work	-	-	NO
4537738	26301250	Paolo Cotogni	2	contributed equally to this work	contributed equally to this work	-	-	NO
5838412	29508945	DW	2	contributed to the manuscript review and approval	contributed to the manuscript review and approval	Wrote the paper	Writing - Review & Editing	YES
5838412	29508945	JNJ	2	contributed to the manuscript review and approval	contributed to the manuscript review and approval	Wrote the paper	Writing - Review & Editing	YES
5838412	29508945	LAM	2	contributed to the manuscript review and approval	contributed to the manuscript review and approval	Wrote the paper	Writing - Review & Editing	YES
5838412	29508945	MH	2	developed the concept, drafted, reviewed and approved the manuscript	developed the concept, drafted, reviewed and approved the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
5838412	29508945	MS	2	developed the concept, drafted, reviewed and approved the manuscript	developed the concept, drafted, reviewed and approved the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
5838412	29508945	RL	2	contributed to the manuscript review and approval	contributed to the manuscript review and approval	Wrote the paper	Writing - Review & Editing	YES
5838412	29508945	SK	2	contributed to the manuscript review and approval	contributed to the manuscript review and approval	Wrote the paper	Writing - Review & Editing	YES
5838412	29508945	SL	2	contributed to the manuscript review and approval|contributed to the manuscript review and approval	contributed to the manuscript review and approval	Wrote the paper	Writing - Review & Editing	YES
5838412	29508945	SL	2	contributed to the manuscript review and approval|contributed to the manuscript review and approval	contributed to the manuscript review and approval	Wrote the paper	Writing - Review & Editing	YES
5838412	29508945	SMC	2	contributed to the manuscript review and approval	contributed to the manuscript review and approval	Wrote the paper	Writing - Review & Editing	YES
5838412	29508945	TG	2	contributed to the manuscript review and approval	contributed to the manuscript review and approval	Wrote the paper	Writing - Review & Editing	YES
5838412	29508945	TM	2	developed the concept, drafted, reviewed and approved the manuscript	developed the concept, drafted, reviewed and approved the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
3426461	22564710	All authors	2	contributed substantially to the scientific process leading to this manuscript	contributed substantially to the scientific process leading to this manuscript	-	-	NO
3426461	22564710	ES	2	critically contributed to the manuscript	critically contributed to the manuscript	-	-	NO
3426461	22564710	GT	2	contributed to the concept and design of the study, data analysis, data interpretation, drafted and revised the manuscript	contributed to the concept and design of the study, data analysis, data interpretation, drafted and revised the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
3426461	22564710	MPG	2	critically contributed to the manuscript	critically contributed to the manuscript	-	-	NO
3426461	22564710	NH	2	contributed to data analysis	contributed to data analysis	Analyzed the data	Formal analysis	YES
3426461	22564710	RC	2	contributed to the concept and design of the study, data analysis, data interpretation, drafted and revised the manuscript	contributed to the concept and design of the study, data analysis, data interpretation, drafted and revised the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
3426461	22564710	SB	2	contributed to the concept and design of the study, data analysis, data interpretation, drafted and revised the manuscript	contributed to the concept and design of the study, data analysis, data interpretation, drafted and revised the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
4409065	25909898	BN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409065	25909898	BN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409065	25909898	BN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409065	25909898	BN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409065	25909898	HL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409065	25909898	HL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409065	25909898	HL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409065	25909898	HL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409065	25909898	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409065	25909898	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409065	25909898	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409065	25909898	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409065	25909898	NT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409065	25909898	NT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409065	25909898	NT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409065	25909898	NT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409065	25909898	NT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409065	25909898	SP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4409065	25909898	SP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409065	25909898	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409065	25909898	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4409065	25909898	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762394	17183650	CG	PLoS5	Designed, conducted, and interpreted histology and immunohistochemistry	Designed, conducted, and interpreted histology and immunohistochemistry	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
1762394	17183650	DP	PLoS5	Performed in vitro and in vivo experiments and tissue processing	Performed in vitro and in vivo experiments and tissue processing	Performed the experiments	Investigation	YES
1762394	17183650	EG	PLoS5	Performed in vitro and in vivo experiments and tissue processing	Performed in vitro and in vivo experiments and tissue processing	Performed the experiments	Investigation	YES
1762394	17183650	JN	PLoS5	Wrote the paper|Designed, conducted, and interpreted histology and immunohistochemistry	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762394	17183650	JN	PLoS5	Wrote the paper|Designed, conducted, and interpreted histology and immunohistochemistry	Designed, conducted, and interpreted histology and immunohistochemistry	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
1762394	17183650	JR	PLoS5	Performed in vitro and in vivo experiments and tissue processing	Performed in vitro and in vivo experiments and tissue processing	Performed the experiments	Investigation	YES
1762394	17183650	KA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Designed and interpreted in vivo experiments|Designed, conducted, and interpreted histology and immunohistochemistry	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762394	17183650	KA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Designed and interpreted in vivo experiments|Designed, conducted, and interpreted histology and immunohistochemistry	Analyzed the data	Analyzed the data	Formal analysis	YES
1762394	17183650	KA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Designed and interpreted in vivo experiments|Designed, conducted, and interpreted histology and immunohistochemistry	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762394	17183650	KA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Designed and interpreted in vivo experiments|Designed, conducted, and interpreted histology and immunohistochemistry	Designed and interpreted in vivo experiments	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
1762394	17183650	KA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Designed and interpreted in vivo experiments|Designed, conducted, and interpreted histology and immunohistochemistry	Designed, conducted, and interpreted histology and immunohistochemistry	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
1762394	17183650	KJ	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762394	17183650	KY	PLoS5	Performed in vitro and in vivo experiments and tissue processing	Performed in vitro and in vivo experiments and tissue processing	Performed the experiments	Investigation	YES
1762394	17183650	MD	PLoS5	Wrote the paper|Designed and interpreted in vivo experiments|Designed and interpreted molecular experiments	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762394	17183650	MD	PLoS5	Wrote the paper|Designed and interpreted in vivo experiments|Designed and interpreted molecular experiments	Designed and interpreted in vivo experiments	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
1762394	17183650	MD	PLoS5	Wrote the paper|Designed and interpreted in vivo experiments|Designed and interpreted molecular experiments	Designed and interpreted molecular experiments	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
1762394	17183650	MM	PLoS5	Performed in vitro and in vivo experiments and tissue processing	Performed in vitro and in vivo experiments and tissue processing	Performed the experiments	Investigation	YES
1762394	17183650	PP	PLoS5	Designed and interpreted in vivo experiments|Edited the manuscript|Designed and interpreted molecular experiments	Designed and interpreted in vivo experiments	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
1762394	17183650	PP	PLoS5	Designed and interpreted in vivo experiments|Edited the manuscript|Designed and interpreted molecular experiments	Edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
1762394	17183650	PP	PLoS5	Designed and interpreted in vivo experiments|Edited the manuscript|Designed and interpreted molecular experiments	Designed and interpreted molecular experiments	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
1762394	17183650	RB	PLoS5	Performed in vitro and in vivo experiments and tissue processing	Performed in vitro and in vivo experiments and tissue processing	Performed the experiments	Investigation	YES
1762394	17183650	SG	PLoS5	Designed, conducted, and interpreted histology and immunohistochemistry	Designed, conducted, and interpreted histology and immunohistochemistry	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6282815	30295338	A.F.D.	PLoS52	made critical revisions of the manuscript|drafted the manuscript and prepared the figures	made critical revisions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
6282815	30295338	A.F.D.	PLoS52	made critical revisions of the manuscript|drafted the manuscript and prepared the figures	drafted the manuscript and prepared the figures	Wrote the paper	Visualization|Writing - Original Draft	YES
6282815	30295338	D.-C.T.	PLoS52	contributed to data acquisition|made critical revisions of the manuscript|drafted the manuscript and prepared the figures	contributed to data acquisition	Performed the experiments	Investigation	YES
6282815	30295338	D.-C.T.	PLoS52	contributed to data acquisition|made critical revisions of the manuscript|drafted the manuscript and prepared the figures	made critical revisions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
6282815	30295338	D.-C.T.	PLoS52	contributed to data acquisition|made critical revisions of the manuscript|drafted the manuscript and prepared the figures	drafted the manuscript and prepared the figures	Wrote the paper	Visualization|Writing - Original Draft	YES
6282815	30295338	F.-D.S.	PLoS52	formulated the conception and design of this study|drafted the manuscript and prepared the figures	formulated the conception and design of this study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6282815	30295338	F.-D.S.	PLoS52	formulated the conception and design of this study|drafted the manuscript and prepared the figures	drafted the manuscript and prepared the figures	Wrote the paper	Visualization|Writing - Original Draft	YES
6282815	30295338	F.D.S.	PLoS52	made critical revisions of the manuscript	made critical revisions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
6282815	30295338	J.Y.	PLoS52	contributed to data acquisition	contributed to data acquisition	Performed the experiments	Investigation	YES
6282815	30295338	K.S.	PLoS52	made critical revisions of the manuscript|drafted the manuscript and prepared the figures	made critical revisions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
6282815	30295338	K.S.	PLoS52	made critical revisions of the manuscript|drafted the manuscript and prepared the figures	drafted the manuscript and prepared the figures	Wrote the paper	Visualization|Writing - Original Draft	YES
6282815	30295338	L.S.	PLoS52	contributed to data acquisition	contributed to data acquisition	Performed the experiments	Investigation	YES
6282815	30295338	M.Z.	PLoS52	contributed to data acquisition	contributed to data acquisition	Performed the experiments	Investigation	YES
6282815	30295338	S.Z.	PLoS52	contributed to data acquisition	contributed to data acquisition	Performed the experiments	Investigation	YES
6282815	30295338	X.Y.	PLoS52	contributed to data acquisition	contributed to data acquisition	Performed the experiments	Investigation	YES
6282815	30295338	Y.F.	PLoS52	formulated the conception and design of this study|made critical revisions of the manuscript	formulated the conception and design of this study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6282815	30295338	Y.F.	PLoS52	formulated the conception and design of this study|made critical revisions of the manuscript	made critical revisions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
6282815	30295338	Z.Z.	PLoS52	contributed to data acquisition	contributed to data acquisition	Performed the experiments	Investigation	YES
6282815	30295338	all authors	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5613136	28983311	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5613136	28983311	BL	PLoS52	designed the research|analyzed the data|wrote the paper	designed the research	Conceived and designed the experiments	Methodology	YES
5613136	28983311	BL	PLoS52	designed the research|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5613136	28983311	BL	PLoS52	designed the research|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5613136	28983311	BZ	PLoS52	contributed reagents and greenhouse facility to the work	contributed reagents and greenhouse facility to the work	Contributed reagents/materials/analysis tools	Resources	YES
5613136	28983311	DL	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5613136	28983311	DW	PLoS52	designed the research|wrote the paper	designed the research	Conceived and designed the experiments	Methodology	YES
5613136	28983311	DW	PLoS52	designed the research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5613136	28983311	HZ	PLoS52	designed the research|analyzed the data|wrote the paper	designed the research	Conceived and designed the experiments	Methodology	YES
5613136	28983311	HZ	PLoS52	designed the research|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5613136	28983311	HZ	PLoS52	designed the research|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5613136	28983311	SL	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5613136	28983311	SL	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5613136	28983311	WC	PLoS52	contributed reagents and greenhouse facility to the work	contributed reagents and greenhouse facility to the work	Contributed reagents/materials/analysis tools	Resources	YES
5613136	28983311	XX	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5613136	28983311	XX	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5613136	28983311	YZ	PLoS52	performed the experiments|analyzed the data|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5613136	28983311	YZ	PLoS52	performed the experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5613136	28983311	YZ	PLoS52	performed the experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5941241	29750184	BMM	PLoS52	conceived and designed the study|recruited, sampled and collected data from patients	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5941241	29750184	BMM	PLoS52	conceived and designed the study|recruited, sampled and collected data from patients	recruited, sampled and collected data from patients	Performed the experiments	Investigation	YES
5941241	29750184	ILR	PLoS52	conceived and designed the study|recruited, sampled and collected data from patients	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5941241	29750184	ILR	PLoS52	conceived and designed the study|recruited, sampled and collected data from patients	recruited, sampled and collected data from patients	Performed the experiments	Investigation	YES
5941241	29750184	JS	PLoS52	conceived and designed the study|recruited, sampled and collected data from patients	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5941241	29750184	JS	PLoS52	conceived and designed the study|recruited, sampled and collected data from patients	recruited, sampled and collected data from patients	Performed the experiments	Investigation	YES
5941241	29750184	KAW	PLoS52	conceived and designed the study|analysed the data|wrote the manuscript, which was revised by all authors	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5941241	29750184	KAW	PLoS52	conceived and designed the study|analysed the data|wrote the manuscript, which was revised by all authors	analysed the data	Analyzed the data	Formal analysis	YES
5941241	29750184	KAW	PLoS52	conceived and designed the study|analysed the data|wrote the manuscript, which was revised by all authors	wrote the manuscript, which was revised by all authors	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5941241	29750184	MN	PLoS52	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5941241	29750184	NP	PLoS52	recruited, sampled and collected data from patients	recruited, sampled and collected data from patients	Performed the experiments	Investigation	YES
5941241	29750184	RJW	PLoS52	conceived and designed the study|analysed the data|wrote the manuscript, which was revised by all authors	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5941241	29750184	RJW	PLoS52	conceived and designed the study|analysed the data|wrote the manuscript, which was revised by all authors	analysed the data	Analyzed the data	Formal analysis	YES
5941241	29750184	RJW	PLoS52	conceived and designed the study|analysed the data|wrote the manuscript, which was revised by all authors	wrote the manuscript, which was revised by all authors	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5421330	28482802	AT	PLoS52	designed and organized the entire research|drafted the manuscript	designed and organized the entire research	Conceived and designed the experiments	Methodology	YES
5421330	28482802	AT	PLoS52	designed and organized the entire research|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5421330	28482802	GW	PLoS52	performed the experiments and acquired the data|analyzed the data	performed the experiments and acquired the data	Performed the experiments	Investigation	YES
5421330	28482802	GW	PLoS52	performed the experiments and acquired the data|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5421330	28482802	JQ	PLoS52	designed and organized the entire research|revised the manuscript critically	designed and organized the entire research	Conceived and designed the experiments	Methodology	YES
5421330	28482802	JQ	PLoS52	designed and organized the entire research|revised the manuscript critically	revised the manuscript critically	Wrote the paper	Writing - Review & Editing	YES
5421330	28482802	JX	PLoS52	performed the experiments and acquired the data|drafted the manuscript	performed the experiments and acquired the data	Performed the experiments	Investigation	YES
5421330	28482802	JX	PLoS52	performed the experiments and acquired the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5421330	28482802	LH	PLoS52	analyzed the data|drafted the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5421330	28482802	LH	PLoS52	analyzed the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5421330	28482802	LL	PLoS52	performed the experiments and acquired the data|revised the manuscript critically	performed the experiments and acquired the data	Performed the experiments	Investigation	YES
5421330	28482802	LL	PLoS52	performed the experiments and acquired the data|revised the manuscript critically	revised the manuscript critically	Wrote the paper	Writing - Review & Editing	YES
5421330	28482802	LZ	PLoS52	analyzed the data|drafted the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5421330	28482802	LZ	PLoS52	analyzed the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5421330	28482802	PF	PLoS52	designed and organized the entire research|revised the manuscript critically	designed and organized the entire research	Conceived and designed the experiments	Methodology	YES
5421330	28482802	PF	PLoS52	designed and organized the entire research|revised the manuscript critically	revised the manuscript critically	Wrote the paper	Writing - Review & Editing	YES
5421330	28482802	PL	PLoS52	performed the experiments and acquired the data|revised the manuscript critically	performed the experiments and acquired the data	Performed the experiments	Investigation	YES
5421330	28482802	PL	PLoS52	performed the experiments and acquired the data|revised the manuscript critically	revised the manuscript critically	Wrote the paper	Writing - Review & Editing	YES
5421330	28482802	RA	PLoS52	analyzed the data|revised the manuscript critically	analyzed the data	Analyzed the data	Formal analysis	YES
5421330	28482802	RA	PLoS52	analyzed the data|revised the manuscript critically	revised the manuscript critically	Wrote the paper	Writing - Review & Editing	YES
3358714	22629288	BRITON	7	design of study, analysis and interpretation of the data, critical revision/drafting of the manuscript, final approval to submit	design of study, analysis and interpretation of the data, critical revision/drafting of the manuscript, final approval to submit	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
3358714	22629288	RICHARD	7	statistical analysis and interpretation, critical revision/drafting of the manuscript, final approval to submit	statistical analysis and interpretation, critical revision/drafting of the manuscript, final approval to submit	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
3358714	22629288	SANDS	7	design of study, analysis and interpretation of the data, critical revision/drafting of the manuscript, final approval to submit	design of study, analysis and interpretation of the data, critical revision/drafting of the manuscript, final approval to submit	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
3358714	22629288	SHELL	7	design of study, analysis and interpretation of the data, critical revision/drafting of the manuscript, final approval to submit	design of study, analysis and interpretation of the data, critical revision/drafting of the manuscript, final approval to submit	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
3358714	22629288	ZHANG	7	statistical analysis and interpretation, critical revision/drafting of the manuscript, final approval to submit	statistical analysis and interpretation, critical revision/drafting of the manuscript, final approval to submit	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
3438085	22682020	MFA	2	helped to adjust the manuscript to fit the journal guidelines and revised the manuscript critically for important intellectual content	helped to adjust the manuscript to fit the journal guidelines and revised the manuscript critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
3438085	22682020	MIM-K	2	participated in the study design, carried out all the experiments, did the statistical analysis, and drafted the manuscript	participated in the study design, carried out all the experiments, did the statistical analysis, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
3438085	22682020	PAS	2	revised the manuscript critically for important intellectual content	revised the manuscript critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
3438085	22682020	PET	2	scans and revised the manuscript critically for important intellectual content	scans and revised the manuscript critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
3438085	22682020	SMA	2	revised the manuscript critically for important intellectual content	revised the manuscript critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
1762395	17183686	CF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762395	17183686	CF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762395	17183686	CF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762395	17183686	CF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762395	17183686	PV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762395	17183686	PV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1762395	17183686	PV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1762395	17183686	PV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409066	25909471	BLMB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409066	25909471	BLMB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409066	25909471	BLMB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409066	25909471	BLMB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409066	25909471	CP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409066	25909471	DN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409066	25909471	DN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409066	25909471	DN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409066	25909471	DN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409066	25909471	ECS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4409066	25909471	ECS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409066	25909471	EL	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4409066	25909471	EL	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409066	25909471	HV	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409066	25909471	HV	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409066	25909471	NV	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5422886	28482796	AHM	2	conceived and completed the bioinformatics pipeline	conceived and completed the bioinformatics pipeline	Conceived and designed the experiments	Conceptualization|Formal analysis	YES
5422886	28482796	BJS	2	designed the study and drafted the manuscript	designed the study and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5422886	28482796	HU	2	conceived and completed the bioinformatics pipeline	conceived and completed the bioinformatics pipeline	Conceived and designed the experiments	Conceptualization|Formal analysis	YES
5422886	28482796	JT	2	conceived and completed the bioinformatics pipeline	conceived and completed the bioinformatics pipeline	Conceived and designed the experiments	Conceptualization|Formal analysis	YES
5422886	28482796	LED	2	designed the study and drafted the manuscript|performed lab work, data analysis|conceived and completed the bioinformatics pipeline	designed the study and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5422886	28482796	LED	2	designed the study and drafted the manuscript|performed lab work, data analysis|conceived and completed the bioinformatics pipeline	performed lab work, data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5422886	28482796	LED	2	designed the study and drafted the manuscript|performed lab work, data analysis|conceived and completed the bioinformatics pipeline	conceived and completed the bioinformatics pipeline	Conceived and designed the experiments	Conceptualization|Formal analysis	YES
6282853	30264411	All authors	2	participated in data collection and analysis	participated in data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6282853	30264411	P.V.	2	conceived and designed the study|drafted the manuscript and figures	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6282853	30264411	P.V.	2	conceived and designed the study|drafted the manuscript and figures	drafted the manuscript and figures	Wrote the paper	Visualization|Writing - Original Draft	YES
6282853	30264411	S.A.P.	2	drafted the manuscript and figures	drafted the manuscript and figures	Wrote the paper	Visualization|Writing - Original Draft	YES
6282853	30264411	T.G.L.	2	drafted the manuscript and figures	drafted the manuscript and figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5613138	28983308	All authors	2	read, commented and approved the manuscript	read, commented and approved the manuscript	-	-	NO
5613138	28983308	EMS	2	population nursery|mutagenesis and m2 population generation, revision and proof reading of the manuscript	population nursery	-	-	NO
5613138	28983308	EMS	2	population nursery|mutagenesis and m2 population generation, revision and proof reading of the manuscript	mutagenesis and m2 population generation, revision and proof reading of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5613138	28983308	UPLC	2	mass spectrometry data acquisition and analysis of lignan extracts, revision of manuscript	mass spectrometry data acquisition and analysis of lignan extracts, revision of manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Formal analysis|Investigation|Writing - Review & Editing	YES
3441325	22863174	AT	2	made the conception and design, as well as the analysis and interpretation of data	made the conception and design, as well as the analysis and interpretation of data	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
3441325	22863174	CU	2	did the analysis and interpretation of data	did the analysis and interpretation of data	Analyzed the data	Formal analysis	YES
3441325	22863174	GB	2	conducted the analysis of data	conducted the analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3441325	22863174	KK	2	is responsible for the animal models and interpretation of data	is responsible for the animal models and interpretation of data	Performed the experiments|Analyzed the data	Formal analysis|Methodology	YES
3441325	22863174	MH	2	made the conception and design, as well as analysis and interpretation of data, revising the manuscript critically for important intellectual content and final approval of the manuscript	made the conception and design, as well as analysis and interpretation of data, revising the manuscript critically for important intellectual content and final approval of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Review & Editing	YES
3441325	22863174	MS	2	carried out the dcm animal models and interpretation of data	carried out the dcm animal models and interpretation of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
3441325	22863174	MW	2	did the analysis and interpretation of data	did the analysis and interpretation of data	Analyzed the data	Formal analysis	YES
3441325	22863174	PC	2	did the revision of the manuscript critically for important intellectual content	did the revision of the manuscript critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
3441325	22863174	SB	2	made the conception and design, as well as the analysis and interpretation of data	made the conception and design, as well as the analysis and interpretation of data	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
3441325	22863174	SL	2	did the analysis and interpretation of data	did the analysis and interpretation of data	Analyzed the data	Formal analysis	YES
3441325	22863174	SN	2	has done the analysis of data and revision of the manuscript critically for important intellectual content	has done the analysis of data and revision of the manuscript critically for important intellectual content	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
3441325	22863174	WF	2	did the revision of the manuscript critically for important intellectual content and the final approval of the manuscript	did the revision of the manuscript critically for important intellectual content and the final approval of the manuscript	Wrote the paper	Writing - Review & Editing	YES
1762396	17183720	FG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762396	17183720	FG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762396	17183720	FG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762396	17183720	FG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762396	17183720	FG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762396	17183720	FV	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1762396	17183720	FV	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762396	17183720	JB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1762396	17183720	JB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762396	17183720	JG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1762396	17183720	JG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762396	17183720	JI	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1762396	17183720	JI	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762396	17183720	JL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1762396	17183720	JL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762396	17183720	LM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1762396	17183720	LM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762396	17183720	ML	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1762396	17183720	ML	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762396	17183720	MM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762396	17183720	MM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762396	17183720	MM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762396	17183720	MM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762396	17183720	MM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762396	17183720	MR	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762396	17183720	MR	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762396	17183720	PV	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1762396	17183720	PV	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762396	17183720	SM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1762396	17183720	SM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762396	17183720	SP	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762396	17183720	SP	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762396	17183720	SP	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762396	17183720	SP	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762396	17183720	SP	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762396	17183720	SP	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762396	17183720	SP	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5839235	29509305	All authors	2	have provided input at all stages of the project and approved the final version	have provided input at all stages of the project and approved the final version	-	-	NO
5839235	29509305	C.I.H.	2	developed the initial analysis protocol|performed study co-ordination and prepared the datasets for analysis|prepared the first draft of the manuscript and completed all revisions	developed the initial analysis protocol	Conceived and designed the experiments	Methodology	YES
5839235	29509305	C.I.H.	2	developed the initial analysis protocol|performed study co-ordination and prepared the datasets for analysis|prepared the first draft of the manuscript and completed all revisions	performed study co-ordination and prepared the datasets for analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Project administration	YES
5839235	29509305	C.I.H.	2	developed the initial analysis protocol|performed study co-ordination and prepared the datasets for analysis|prepared the first draft of the manuscript and completed all revisions	prepared the first draft of the manuscript and completed all revisions	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5839235	29509305	C.S.	2	developed the initial analysis protocol|performed the statistical analysis|provided critical input at all stages of the preparation of the manuscript	developed the initial analysis protocol	Conceived and designed the experiments	Methodology	YES
5839235	29509305	C.S.	2	developed the initial analysis protocol|performed the statistical analysis|provided critical input at all stages of the preparation of the manuscript	performed the statistical analysis	Analyzed the data	Formal analysis	YES
5839235	29509305	C.S.	2	developed the initial analysis protocol|performed the statistical analysis|provided critical input at all stages of the preparation of the manuscript	provided critical input at all stages of the preparation of the manuscript	Wrote the paper	Writing - Original Draft	YES
5839235	29509305	J.D.L.	2	developed the initial analysis protocol|provided critical input at all stages of the preparation of the manuscript	developed the initial analysis protocol	Conceived and designed the experiments	Methodology	YES
5839235	29509305	J.D.L.	2	developed the initial analysis protocol|provided critical input at all stages of the preparation of the manuscript	provided critical input at all stages of the preparation of the manuscript	Wrote the paper	Writing - Original Draft	YES
5839235	29509305	L.R.	2	developed the initial analysis protocol|performed study co-ordination and prepared the datasets for analysis|provided critical input at all stages of the preparation of the manuscript	developed the initial analysis protocol	Conceived and designed the experiments	Methodology	YES
5839235	29509305	L.R.	2	developed the initial analysis protocol|performed study co-ordination and prepared the datasets for analysis|provided critical input at all stages of the preparation of the manuscript	performed study co-ordination and prepared the datasets for analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Project administration	YES
5839235	29509305	L.R.	2	developed the initial analysis protocol|performed study co-ordination and prepared the datasets for analysis|provided critical input at all stages of the preparation of the manuscript	provided critical input at all stages of the preparation of the manuscript	Wrote the paper	Writing - Original Draft	YES
4409067	25909989	AU	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409067	25909989	AU	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409067	25909989	MZ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409067	25909989	MZ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409067	25909989	MZ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409067	25909989	PS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409067	25909989	PS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409067	25909989	PS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3441881	22809406	AA	2	provided the concept for the review and critically reviewed and edited the manuscript	provided the concept for the review and critically reviewed and edited the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
3441881	22809406	ALBB	2	reviewed the current literature and wrote the manuscript	reviewed the current literature and wrote the manuscript	Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
3441881	22809406	AT	2	critically reviewed the manuscript	critically reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
3441881	22809406	BS	2	critically reviewed the manuscript	critically reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
3441881	22809406	VNC	2	critically reviewed the manuscript	critically reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
1762397	17183690	ET	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762397	17183690	ET	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762397	17183690	FY	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762397	17183690	FY	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762397	17183690	JQ	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762397	17183690	JQ	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762397	17183690	KY	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762397	17183690	KY	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762397	17183690	MS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762397	17183690	MS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762397	17183690	QL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762397	17183690	QL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762397	17183690	QL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762397	17183690	RE	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762397	17183690	RE	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762397	17183690	SL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762397	17183690	SL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762397	17183690	SL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762397	17183690	SL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762397	17183690	YY	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762397	17183690	YY	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5850046	29537178	EHL	7	data analysis, data interpretation, writing	data analysis, data interpretation, writing	Analyzed the data|Wrote the paper	Formal analysis	YES
5850046	29537178	HO	7	data analysis	data analysis	Analyzed the data	Formal analysis	YES
5850046	29537178	JF	7	study design, data interpretation, writing	study design, data interpretation, writing	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology	YES
5850046	29537178	PWC	7	study design, data interpretation, writing	study design, data interpretation, writing	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology	YES
5850046	29537178	SBM	7	study design, data interpretation, writing	study design, data interpretation, writing	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology	YES
5850046	29537178	WME	7	study design, data interpretation, writing	study design, data interpretation, writing	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology	YES
5850046	29537178	YHM	7	study design, data interpretation, writing	study design, data interpretation, writing	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology	YES
6282982	30196548	All authors	2	contributed to data acquisition and analysis|critically evaluated and approved the manuscript	contributed to data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6282982	30196548	All authors	2	contributed to data acquisition and analysis|critically evaluated and approved the manuscript	critically evaluated and approved the manuscript	-	-	NO
6282982	30196548	C.E.T.	2	contributed to study concept and design|contributed to drafting the text and figures	contributed to study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6282982	30196548	C.E.T.	2	contributed to study concept and design|contributed to drafting the text and figures	contributed to drafting the text and figures	Wrote the paper	Visualization|Writing - Original Draft	YES
6282982	30196548	I.M.W.V.	2	contributed to study concept and design|contributed to drafting the text and figures	contributed to study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6282982	30196548	I.M.W.V.	2	contributed to study concept and design|contributed to drafting the text and figures	contributed to drafting the text and figures	Wrote the paper	Visualization|Writing - Original Draft	YES
6282982	30196548	P.S.	2	contributed to study concept and design	contributed to study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6282982	30196548	W.M.v.d.F.	2	contributed to study concept and design|contributed to drafting the text and figures	contributed to study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6282982	30196548	W.M.v.d.F.	2	contributed to study concept and design|contributed to drafting the text and figures	contributed to drafting the text and figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5422975	28482799	AL	CRediT	Conceptualization|Data curation|Formal analysis|Investigation|Methodology|Project administration|Resources|Software|Supervision|Validation|Visualization|Writing - original draft|Writing - review & editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
5422975	28482799	AL	CRediT	Conceptualization|Data curation|Formal analysis|Investigation|Methodology|Project administration|Resources|Software|Supervision|Validation|Visualization|Writing - original draft|Writing - review & editing	Data curation	Analyzed the data	Data curation	YES
5422975	28482799	AL	CRediT	Conceptualization|Data curation|Formal analysis|Investigation|Methodology|Project administration|Resources|Software|Supervision|Validation|Visualization|Writing - original draft|Writing - review & editing	Formal analysis	Analyzed the data	Formal analysis	YES
5422975	28482799	AL	CRediT	Conceptualization|Data curation|Formal analysis|Investigation|Methodology|Project administration|Resources|Software|Supervision|Validation|Visualization|Writing - original draft|Writing - review & editing	Investigation	Performed the experiments	Investigation	YES
5422975	28482799	AL	CRediT	Conceptualization|Data curation|Formal analysis|Investigation|Methodology|Project administration|Resources|Software|Supervision|Validation|Visualization|Writing - original draft|Writing - review & editing	Methodology	Performed the experiments	Methodology	YES
5422975	28482799	AL	CRediT	Conceptualization|Data curation|Formal analysis|Investigation|Methodology|Project administration|Resources|Software|Supervision|Validation|Visualization|Writing - original draft|Writing - review & editing	Project administration	-	Project administration	YES
5422975	28482799	AL	CRediT	Conceptualization|Data curation|Formal analysis|Investigation|Methodology|Project administration|Resources|Software|Supervision|Validation|Visualization|Writing - original draft|Writing - review & editing	Resources	Contributed reagents/materials/analysis tools	Resources	YES
5422975	28482799	AL	CRediT	Conceptualization|Data curation|Formal analysis|Investigation|Methodology|Project administration|Resources|Software|Supervision|Validation|Visualization|Writing - original draft|Writing - review & editing	Software	Contributed reagents/materials/analysis tools	Software	YES
5422975	28482799	AL	CRediT	Conceptualization|Data curation|Formal analysis|Investigation|Methodology|Project administration|Resources|Software|Supervision|Validation|Visualization|Writing - original draft|Writing - review & editing	Supervision	-	Supervision	YES
5422975	28482799	AL	CRediT	Conceptualization|Data curation|Formal analysis|Investigation|Methodology|Project administration|Resources|Software|Supervision|Validation|Visualization|Writing - original draft|Writing - review & editing	Validation	Performed the experiments	Validation	YES
5422975	28482799	AL	CRediT	Conceptualization|Data curation|Formal analysis|Investigation|Methodology|Project administration|Resources|Software|Supervision|Validation|Visualization|Writing - original draft|Writing - review & editing	Visualization	Analyzed the data	Visualization	YES
5422975	28482799	AL	CRediT	Conceptualization|Data curation|Formal analysis|Investigation|Methodology|Project administration|Resources|Software|Supervision|Validation|Visualization|Writing - original draft|Writing - review & editing	Writing - original draft	Wrote the paper	Writing - Original Draft	YES
5422975	28482799	AL	CRediT	Conceptualization|Data curation|Formal analysis|Investigation|Methodology|Project administration|Resources|Software|Supervision|Validation|Visualization|Writing - original draft|Writing - review & editing	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
5422975	28482799	AP	CRediT	Data curation|Writing - review & editing	Data curation	Analyzed the data	Data curation	YES
5422975	28482799	AP	CRediT	Data curation|Writing - review & editing	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
5422975	28482799	DG	CRediT	Formal analysis|Writing - review & editing	Formal analysis	Analyzed the data	Formal analysis	YES
5422975	28482799	DG	CRediT	Formal analysis|Writing - review & editing	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
5422975	28482799	JV	CRediT	Formal analysis|Writing - review & editing	Formal analysis	Analyzed the data	Formal analysis	YES
5422975	28482799	JV	CRediT	Formal analysis|Writing - review & editing	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
5422975	28482799	RD	CRediT	Resources|Writing - review & editing	Resources	Contributed reagents/materials/analysis tools	Resources	YES
5422975	28482799	RD	CRediT	Resources|Writing - review & editing	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
5422975	28482799	UD	CRediT	Conceptualization|Funding acquisition|Resources|Supervision|Writing - review & editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
5422975	28482799	UD	CRediT	Conceptualization|Funding acquisition|Resources|Supervision|Writing - review & editing	Funding acquisition	-	Funding acquisition	YES
5422975	28482799	UD	CRediT	Conceptualization|Funding acquisition|Resources|Supervision|Writing - review & editing	Resources	Contributed reagents/materials/analysis tools	Resources	YES
5422975	28482799	UD	CRediT	Conceptualization|Funding acquisition|Resources|Supervision|Writing - review & editing	Supervision	-	Supervision	YES
5422975	28482799	UD	CRediT	Conceptualization|Funding acquisition|Resources|Supervision|Writing - review & editing	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
5613158	28983309	AB	2	designed the article, drafted the entire manuscript and arranged the references	designed the article, drafted the entire manuscript and arranged the references	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
5613158	28983309	AR	2	suggested the title of the opinion article|incorporated all the necessary modifications	suggested the title of the opinion article	-	-	NO
5613158	28983309	AR	2	suggested the title of the opinion article|incorporated all the necessary modifications	incorporated all the necessary modifications	-	-	NO
5613158	28983309	All the authors	2	checked and confirmed the final version of the manuscript	checked and confirmed the final version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5613158	28983309	SW	2	suggested the title of the opinion article	suggested the title of the opinion article	-	-	NO
3444322	22682265	AAL	2	were involved in the acquisition and interpretation of the pet studies and critically revised the manuscript	were involved in the acquisition and interpretation of the pet studies and critically revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
3444322	22682265	BNMB	2	were involved in the acquisition and interpretation of the pet studies and critically revised the manuscript	were involved in the acquisition and interpretation of the pet studies and critically revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
3444322	22682265	CHF	2	was involved in the acquisition and interpretation of the tcd studies and critically revised the manuscript	was involved in the acquisition and interpretation of the tcd studies and critically revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
3444322	22682265	CJMK	2	participated in the design of the study, interpreted the data and critically revised the manuscript	participated in the design of the study, interpreted the data and critically revised the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
3444322	22682265	LJK	2	participated in the design of the study, interpreted the data and critically revised the manuscript	participated in the design of the study, interpreted the data and critically revised the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
3444322	22682265	RB	2	were involved in the acquisition and interpretation of the pet studies and critically revised the manuscript	were involved in the acquisition and interpretation of the pet studies and critically revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
3444322	22682265	SP	2	participated in the design of the study, performed the statistical analysis, and drafted the manuscript	participated in the design of the study, performed the statistical analysis, and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4409068	25909482	JT	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409068	25909482	JT	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409068	25909482	JT	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409068	25909482	OP	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409068	25909482	OP	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409068	25909482	PDJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409068	25909482	PDJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409068	25909482	PDJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409068	25909482	PDJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409068	25909482	SN	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409068	25909482	TC	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409068	25909482	TC	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5851343	29537628	All authors	2	contributed and approved the final version	contributed and approved the final version	-	-	NO
5851343	29537628	PE	2	wrote the first draft	wrote the first draft	Wrote the paper	Writing - Original Draft	YES
1762398	17183667	AA	PLoS5	Performed the experiments|Programmed the virtual environment	Performed the experiments	Performed the experiments	Investigation	YES
1762398	17183667	AA	PLoS5	Performed the experiments|Programmed the virtual environment	Programmed the virtual environment	Contributed reagents/materials/analysis tools	Software	YES
1762398	17183667	AD	PLoS5	Programmed the virtual environment	Programmed the virtual environment	Contributed reagents/materials/analysis tools	Software	YES
1762398	17183667	CB	PLoS5	Contributed reagents/materials/analysis tools|Helped in the design of the experiment	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762398	17183667	CB	PLoS5	Contributed reagents/materials/analysis tools|Helped in the design of the experiment	Helped in the design of the experiment	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
1762398	17183667	CG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1762398	17183667	CG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762398	17183667	DS	PLoS5	Provided system support, critical comments, and prepared multi-media materials for the paper	Provided system support, critical comments, and prepared multi-media materials for the paper	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Resources|Writing - Original Draft	YES
1762398	17183667	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762398	17183667	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762398	17183667	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762398	17183667	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762398	17183667	MS-V	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper|Helped in the design of the experiment	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762398	17183667	MS-V	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper|Helped in the design of the experiment	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762398	17183667	MS-V	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper|Helped in the design of the experiment	Helped in the design of the experiment	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
1762398	17183667	NP	PLoS5	Helped in the design of the experiment	Helped in the design of the experiment	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3444346	22682159	AJ	2	performed the mc simulations and drafted the manuscript	performed the mc simulations and drafted the manuscript	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3444346	22682159	Both authors	2	designed the study|contributed to the scientific and intellectual discussion and interpretation of the data and revision of the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
3444346	22682159	Both authors	2	designed the study|contributed to the scientific and intellectual discussion and interpretation of the data and revision of the manuscript	contributed to the scientific and intellectual discussion and interpretation of the data and revision of the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
5613161	28983305	AKS	PLoS52	directed field efforts and phenotyping|analyzed the data	directed field efforts and phenotyping	Performed the experiments	Investigation|Supervision	YES
5613161	28983305	AKS	PLoS52	directed field efforts and phenotyping|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5613161	28983305	AS	PLoS52	directed field efforts and phenotyping	directed field efforts and phenotyping	Performed the experiments	Investigation|Supervision	YES
5613161	28983305	All authors	PLoS52	contributed to the preparation and development of manuscript	contributed to the preparation and development of manuscript	Wrote the paper	Writing - Original Draft	YES
5613161	28983305	JZ	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5613161	28983305	RC	PLoS52	collected phenotypic data|analyzed the data	collected phenotypic data	Performed the experiments	Investigation	YES
5613161	28983305	RC	PLoS52	collected phenotypic data|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5613161	28983305	SC	PLoS52	collected phenotypic data|analyzed the data	collected phenotypic data	Performed the experiments	Investigation	YES
5613161	28983305	SC	PLoS52	collected phenotypic data|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5422989	28482814	HG	2	developed the tilling population and wrote the manuscript|measured chlorophyll fluorescence parameters and prepared the drafting manuscript	developed the tilling population and wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5422989	28482814	HG	2	developed the tilling population and wrote the manuscript|measured chlorophyll fluorescence parameters and prepared the drafting manuscript	measured chlorophyll fluorescence parameters and prepared the drafting manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5422989	28482814	HX	2	prepared figures	prepared figures	-	Visualization	YES
5422989	28482814	JG	2	managed plant materials	managed plant materials	Performed the experiments	Investigation	YES
5422989	28482814	LL	2	conceived the original research, supervised data generation and analyses and wrote the manuscript	conceived the original research, supervised data generation and analyses and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Supervision|Writing - Original Draft	YES
5422989	28482814	LZ	2	managed plant materials	managed plant materials	Performed the experiments	Investigation	YES
5422989	28482814	SZ	2	managed plant materials	managed plant materials	Performed the experiments	Investigation	YES
5422989	28482814	XL	2	screened the alleles|designed the specific primers	screened the alleles	Performed the experiments	Investigation	YES
5422989	28482814	XL	2	screened the alleles|designed the specific primers	designed the specific primers	Conceived and designed the experiments	-	YES
5422989	28482814	YL	2	designed the specific primers|carried out the rt-qpcr and microscopy analysis|measured chlorophyll fluorescence parameters and prepared the drafting manuscript	designed the specific primers	Conceived and designed the experiments	-	YES
5422989	28482814	YL	2	designed the specific primers|carried out the rt-qpcr and microscopy analysis|measured chlorophyll fluorescence parameters and prepared the drafting manuscript	carried out the rt-qpcr and microscopy analysis	Performed the experiments	Investigation	YES
5422989	28482814	YL	2	designed the specific primers|carried out the rt-qpcr and microscopy analysis|measured chlorophyll fluorescence parameters and prepared the drafting manuscript	measured chlorophyll fluorescence parameters and prepared the drafting manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5422989	28482814	YX	2	prepared figures	prepared figures	-	Visualization	YES
5422989	28482814	ZY	2	developed the tilling population and wrote the manuscript	developed the tilling population and wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4409069	25909853	GW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409069	25909853	GW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409069	25909853	GW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409069	25909853	GW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409069	25909853	JT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409069	25909853	JT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4409069	25909853	JT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409069	25909853	KLH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409069	25909853	KLH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409069	25909853	KLH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409069	25909853	LQ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409069	25909853	LQ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4409069	25909853	LQ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4409069	25909853	LQ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409069	25909853	MW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409069	25909853	MW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4409069	25909853	MW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409069	25909853	ST	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409069	25909853	ST	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409069	25909853	ST	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409069	25909853	ST	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5851344	29537654	FTP	2	analysed the data and developed the cost-effectiveness model|wrote and revised the manuscript	analysed the data and developed the cost-effectiveness model	Performed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5851344	29537654	FTP	2	analysed the data and developed the cost-effectiveness model|wrote and revised the manuscript	wrote and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5851344	29537654	GMR	2	wrote and revised the manuscript	wrote and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5851344	29537654	MC	2	wrote and revised the manuscript	wrote and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5851344	29537654	MKB	2	wrote and revised the manuscript	wrote and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5851344	29537654	MM	2	wrote and revised the manuscript	wrote and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5851344	29537654	MQ	2	analysed the data and developed the cost-effectiveness model|wrote and revised the manuscript	analysed the data and developed the cost-effectiveness model	Performed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5851344	29537654	MQ	2	analysed the data and developed the cost-effectiveness model|wrote and revised the manuscript	wrote and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5851344	29537654	PV	2	analysed the data and developed the cost-effectiveness model|wrote and revised the manuscript	analysed the data and developed the cost-effectiveness model	Performed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5851344	29537654	PV	2	analysed the data and developed the cost-effectiveness model|wrote and revised the manuscript	wrote and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5851344	29537654	RE	2	wrote and revised the manuscript	wrote and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5851344	29537654	SDM	2	wrote and revised the manuscript	wrote and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3444359	22541756	AH	2	did the biological characterisation	did the biological characterisation	Performed the experiments	Investigation	YES
3444359	22541756	BH	2	conceived of the study and participated in its coordination	conceived of the study and participated in its coordination	Conceived and designed the experiments	Conceptualization|Project administration	YES
3444359	22541756	ES	2	designed the experiments, handled the coordination and edited the manuscript	designed the experiments, handled the coordination and edited the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Review & Editing	YES
3444359	22541756	HK	2	participated in the design, carried out the chemical syntheses and drafted the manuscript	participated in the design, carried out the chemical syntheses and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3444359	22541756	LS	2	helped with the hplc and mass spectroscopy experiments	helped with the hplc and mass spectroscopy experiments	Performed the experiments	Investigation	YES
3444359	22541756	RM	2	helped with the radioactive labelling and quantification	helped with the radioactive labelling and quantification	-	-	NO
3444359	22541756	UH	2	helped with the hplc and mass spectroscopy experiments	helped with the hplc and mass spectroscopy experiments	Performed the experiments	Investigation	YES
1762399	17183724	GS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762399	17183724	GS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762399	17183724	GS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762399	17183724	JS	PLoS5	Analyzed the data|Wrote the paper|Spohn	Analyzed the data	Analyzed the data	Formal analysis	YES
1762399	17183724	JS	PLoS5	Analyzed the data|Wrote the paper|Spohn	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762399	17183724	JS	PLoS5	Analyzed the data|Wrote the paper|Spohn	Spohn	-	-	NO
1762399	17183724	SB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762399	17183724	SB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762399	17183724	SB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762399	17183724	TA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762399	17183724	TA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762399	17183724	TA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409070	25909814	AM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409070	25909814	HM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409070	25909814	HM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409070	25909814	HM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409070	25909814	HM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409070	25909814	IH	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409070	25909814	KA	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409070	25909814	KF	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409070	25909814	KT	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409070	25909814	KY	PLoS5	Advised on experimental design	Advised on experimental design	Conceived and designed the experiments	Methodology	YES
4409070	25909814	MK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409070	25909814	TM	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409070	25909814	TM	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3444360	22846374	All authors	2	participated in the manuscript drafting and approval	participated in the manuscript drafting and approval	Wrote the paper	Writing - Original Draft	YES
3444360	22846374	BB	2	designed the study and performed the data analysis	designed the study and performed the data analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
3444360	22846374	MP	2	performed the literature search and data analysis	performed the literature search and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3444360	22846374	PW	2	designed the study, performed the patient recruitment, data acquisition, and data analysis, and coordinated the study	designed the study, performed the patient recruitment, data acquisition, and data analysis, and coordinated the study	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology|Project administration	YES
3444360	22846374	RW	2	performed the data analysis|performed the data processing and data analysis	performed the data analysis	Analyzed the data	Formal analysis	YES
3444360	22846374	RW	2	performed the data analysis|performed the data processing and data analysis	performed the data processing and data analysis	Analyzed the data	Data curation|Formal analysis	YES
3444360	22846374	SH	2	performed the data acquisition and data processing	performed the data acquisition and data processing	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5613164	28983307	BN	2	performed the experiment	performed the experiment	Performed the experiments	Investigation	YES
5613164	28983307	DL	2	designed and revised the manuscript	designed and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Review & Editing	YES
5613164	28983307	FX	2	collected and analyzed data	collected and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5613164	28983307	GD	2	collected and analyzed data	collected and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5613164	28983307	JG	2	collected and analyzed data	collected and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5613164	28983307	XX	2	performed the experiment and drew the graphs	performed the experiment and drew the graphs	Performed the experiments	Investigation	YES
5613164	28983307	XY	2	designed and performed the experiment, and wrote the manuscript	designed and performed the experiment, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5613164	28983307	YW	2	collected and analyzed data	collected and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5613164	28983307	YZ	2	performed the experiment	performed the experiment	Performed the experiments	Investigation	YES
5613164	28983307	ZZ	2	performed the experiment	performed the experiment	Performed the experiments	Investigation	YES
5613164	28983307	all the authors	2	reviewed and approved this submission	reviewed and approved this submission	-	-	NO
5690239	29546114	All authors	2	reviewed, contributed to and approved the final version of the manuscript	reviewed, contributed to and approved the final version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5690239	29546114	CBP	2	supported decisions during data analysis	supported decisions during data analysis	Analyzed the data	Formal analysis	YES
5690239	29546114	CM	2	designed research	designed research	Conceived and designed the experiments	Methodology	YES
5690239	29546114	ET	2	was responsible for calculation of dietary intake	was responsible for calculation of dietary intake	Analyzed the data	Formal analysis	YES
5690239	29546114	KFM	2	designed research	designed research	Conceived and designed the experiments	Methodology	YES
5690239	29546114	KTE	2	participated in project management and data collection	participated in project management and data collection	Performed the experiments|Analyzed the data	Data curation|Investigation|Project administration	YES
5690239	29546114	LBBA	2	analysed data and wrote the draft of the paper	analysed data and wrote the draft of the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5690239	29546114	RB	2	supported decisions during data analysis	supported decisions during data analysis	Analyzed the data	Formal analysis	YES
1762400	17183671	EG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762400	17183671	EG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762400	17183671	EG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762400	17183671	ES	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762400	17183671	ES	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762400	17183671	ES	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762400	17183671	ES	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762400	17183671	ES	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762400	17183671	FC	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762400	17183671	JD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762400	17183671	JD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1762400	17183671	JD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1762400	17183671	JD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762400	17183671	JP	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1762400	17183671	JP	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1762400	17183671	JP	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762400	17183671	MH	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1762400	17183671	MH	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762400	17183671	MS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1762400	17183671	MS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1762400	17183671	MS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5423416	28486975	CWE	1	Conceived and designed the study|Contributed samples from the msu pig resource population	Conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5423416	28486975	CWE	1	Conceived and designed the study|Contributed samples from the msu pig resource population	Contributed samples from the msu pig resource population	Contributed reagents/materials/analysis tools	Resources	YES
5423416	28486975	DS	1	Performed qpcr assays and analysis	Performed qpcr assays and analysis	Performed the experiments	Investigation	YES
5423416	28486975	JPS	1	Developed software and analysis pipeline	Developed software and analysis pipeline	Contributed reagents/materials/analysis tools	Software	YES
5423416	28486975	NER	1	Contributed samples from the msu pig resource population|Performed qpcr assays and analysis	Contributed samples from the msu pig resource population	Contributed reagents/materials/analysis tools	Resources	YES
5423416	28486975	NER	1	Contributed samples from the msu pig resource population|Performed qpcr assays and analysis	Performed qpcr assays and analysis	Performed the experiments	Investigation	YES
5423416	28486975	ROB	1	Contributed samples from the msu pig resource population	Contributed samples from the msu pig resource population	Contributed reagents/materials/analysis tools	Resources	YES
5423416	28486975	SAF	1	Developed software and analysis pipeline|Performed qpcr assays and analysis|Wrote the manuscript	Developed software and analysis pipeline	Contributed reagents/materials/analysis tools	Software	YES
5423416	28486975	SAF	1	Developed software and analysis pipeline|Performed qpcr assays and analysis|Wrote the manuscript	Performed qpcr assays and analysis	Performed the experiments	Investigation	YES
5423416	28486975	SAF	1	Developed software and analysis pipeline|Performed qpcr assays and analysis|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3444390	22731662	All authors	2	reviewed the manuscript in preparation and approved the final version for submission	reviewed the manuscript in preparation and approved the final version for submission	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3444390	22731662	BK	2	participated in the design of the study, performed statistical analyses, and drafted the manuscript	participated in the design of the study, performed statistical analyses, and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3444390	22731662	DM	2	conceived of the study|participated in the study design and conduct, and drafting of the manuscript	conceived of the study	Conceived and designed the experiments	Conceptualization	YES
3444390	22731662	DM	2	conceived of the study|participated in the study design and conduct, and drafting of the manuscript	participated in the study design and conduct, and drafting of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
3444390	22731662	ER	2	participated in study conduct and recruitment	participated in study conduct and recruitment	Performed the experiments	Investigation	YES
3444390	22731662	ES	2	participated in study coordination, image analysis, and data analysis	participated in study coordination, image analysis, and data analysis	Analyzed the data	Formal analysis|Project administration|Visualization	YES
3444390	22731662	HL	2	conceived of the study|participated in the study design and conduct, and drafting of the manuscript	conceived of the study	Conceived and designed the experiments	Conceptualization	YES
3444390	22731662	HL	2	conceived of the study|participated in the study design and conduct, and drafting of the manuscript	participated in the study design and conduct, and drafting of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
3444390	22731662	JS	2	participated in study conduct and recruitment	participated in study conduct and recruitment	Performed the experiments	Investigation	YES
3444390	22731662	LP	2	participated in study coordination, image analysis, and data analysis	participated in study coordination, image analysis, and data analysis	Analyzed the data	Formal analysis|Project administration|Visualization	YES
3444390	22731662	RL	2	conceived of the study	conceived of the study	Conceived and designed the experiments	Conceptualization	YES
3444390	22731662	VG	2	participated in study conduct and recruitment	participated in study conduct and recruitment	Performed the experiments	Investigation	YES
3444390	22731662	XC	2	participated in study coordination, image analysis, and data analysis	participated in study coordination, image analysis, and data analysis	Analyzed the data	Formal analysis|Project administration|Visualization	YES
5864576	29569354	BG	PLoS52	conceived and designed the study|contributed to the critical appraisal of the manuscript|approved the final version of the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5864576	29569354	BG	PLoS52	conceived and designed the study|contributed to the critical appraisal of the manuscript|approved the final version of the manuscript	contributed to the critical appraisal of the manuscript	-	-	NO
5864576	29569354	BG	PLoS52	conceived and designed the study|contributed to the critical appraisal of the manuscript|approved the final version of the manuscript	approved the final version of the manuscript	-	-	NO
5864576	29569354	BS	PLoS52	conceived and designed the study|analysed the data|contributed to the critical appraisal of the manuscript|approved the final version of the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5864576	29569354	BS	PLoS52	conceived and designed the study|analysed the data|contributed to the critical appraisal of the manuscript|approved the final version of the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
5864576	29569354	BS	PLoS52	conceived and designed the study|analysed the data|contributed to the critical appraisal of the manuscript|approved the final version of the manuscript	contributed to the critical appraisal of the manuscript	-	-	NO
5864576	29569354	BS	PLoS52	conceived and designed the study|analysed the data|contributed to the critical appraisal of the manuscript|approved the final version of the manuscript	approved the final version of the manuscript	-	-	NO
5864576	29569354	CM	PLoS52	conceived and designed the study|contributed to the critical appraisal of the manuscript|approved the final version of the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5864576	29569354	CM	PLoS52	conceived and designed the study|contributed to the critical appraisal of the manuscript|approved the final version of the manuscript	contributed to the critical appraisal of the manuscript	-	-	NO
5864576	29569354	CM	PLoS52	conceived and designed the study|contributed to the critical appraisal of the manuscript|approved the final version of the manuscript	approved the final version of the manuscript	-	-	NO
5864576	29569354	DP	PLoS52	conceived and designed the study|contributed to the critical appraisal of the manuscript|approved the final version of the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5864576	29569354	DP	PLoS52	conceived and designed the study|contributed to the critical appraisal of the manuscript|approved the final version of the manuscript	contributed to the critical appraisal of the manuscript	-	-	NO
5864576	29569354	DP	PLoS52	conceived and designed the study|contributed to the critical appraisal of the manuscript|approved the final version of the manuscript	approved the final version of the manuscript	-	-	NO
5864576	29569354	EG	PLoS52	conceived and designed the study|performed data abstraction|analysed the data|contributed to the critical appraisal of the manuscript|approved the final version of the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5864576	29569354	EG	PLoS52	conceived and designed the study|performed data abstraction|analysed the data|contributed to the critical appraisal of the manuscript|approved the final version of the manuscript	performed data abstraction	-	-	NO
5864576	29569354	EG	PLoS52	conceived and designed the study|performed data abstraction|analysed the data|contributed to the critical appraisal of the manuscript|approved the final version of the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
5864576	29569354	EG	PLoS52	conceived and designed the study|performed data abstraction|analysed the data|contributed to the critical appraisal of the manuscript|approved the final version of the manuscript	contributed to the critical appraisal of the manuscript	-	-	NO
5864576	29569354	EG	PLoS52	conceived and designed the study|performed data abstraction|analysed the data|contributed to the critical appraisal of the manuscript|approved the final version of the manuscript	approved the final version of the manuscript	-	-	NO
5864576	29569354	GC	PLoS52	conceived and designed the study|performed data abstraction|analysed the data|wrote the draft manuscript|contributed to the critical appraisal of the manuscript|approved the final version of the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5864576	29569354	GC	PLoS52	conceived and designed the study|performed data abstraction|analysed the data|wrote the draft manuscript|contributed to the critical appraisal of the manuscript|approved the final version of the manuscript	performed data abstraction	-	-	NO
5864576	29569354	GC	PLoS52	conceived and designed the study|performed data abstraction|analysed the data|wrote the draft manuscript|contributed to the critical appraisal of the manuscript|approved the final version of the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
5864576	29569354	GC	PLoS52	conceived and designed the study|performed data abstraction|analysed the data|wrote the draft manuscript|contributed to the critical appraisal of the manuscript|approved the final version of the manuscript	wrote the draft manuscript	Wrote the paper	Writing - Original Draft	YES
5864576	29569354	GC	PLoS52	conceived and designed the study|performed data abstraction|analysed the data|wrote the draft manuscript|contributed to the critical appraisal of the manuscript|approved the final version of the manuscript	contributed to the critical appraisal of the manuscript	-	-	NO
5864576	29569354	GC	PLoS52	conceived and designed the study|performed data abstraction|analysed the data|wrote the draft manuscript|contributed to the critical appraisal of the manuscript|approved the final version of the manuscript	approved the final version of the manuscript	-	-	NO
5864576	29569354	JC	PLoS52	analysed the data|wrote the draft manuscript|contributed to the critical appraisal of the manuscript|approved the final version of the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
5864576	29569354	JC	PLoS52	analysed the data|wrote the draft manuscript|contributed to the critical appraisal of the manuscript|approved the final version of the manuscript	wrote the draft manuscript	Wrote the paper	Writing - Original Draft	YES
5864576	29569354	JC	PLoS52	analysed the data|wrote the draft manuscript|contributed to the critical appraisal of the manuscript|approved the final version of the manuscript	contributed to the critical appraisal of the manuscript	-	-	NO
5864576	29569354	JC	PLoS52	analysed the data|wrote the draft manuscript|contributed to the critical appraisal of the manuscript|approved the final version of the manuscript	approved the final version of the manuscript	-	-	NO
5864576	29569354	JS	PLoS52	conceived and designed the study|contributed to the critical appraisal of the manuscript|approved the final version of the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5864576	29569354	JS	PLoS52	conceived and designed the study|contributed to the critical appraisal of the manuscript|approved the final version of the manuscript	contributed to the critical appraisal of the manuscript	-	-	NO
5864576	29569354	JS	PLoS52	conceived and designed the study|contributed to the critical appraisal of the manuscript|approved the final version of the manuscript	approved the final version of the manuscript	-	-	NO
5864576	29569354	JWP	PLoS52	conceived and designed the study|contributed to the critical appraisal of the manuscript|approved the final version of the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5864576	29569354	JWP	PLoS52	conceived and designed the study|contributed to the critical appraisal of the manuscript|approved the final version of the manuscript	contributed to the critical appraisal of the manuscript	-	-	NO
5864576	29569354	JWP	PLoS52	conceived and designed the study|contributed to the critical appraisal of the manuscript|approved the final version of the manuscript	approved the final version of the manuscript	-	-	NO
5864576	29569354	KJ	PLoS52	conceived and designed the study|performed data abstraction|contributed to data management|contributed to the critical appraisal of the manuscript|approved the final version of the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5864576	29569354	KJ	PLoS52	conceived and designed the study|performed data abstraction|contributed to data management|contributed to the critical appraisal of the manuscript|approved the final version of the manuscript	performed data abstraction	-	-	NO
5864576	29569354	KJ	PLoS52	conceived and designed the study|performed data abstraction|contributed to data management|contributed to the critical appraisal of the manuscript|approved the final version of the manuscript	contributed to data management	Analyzed the data	Data curation	YES
5864576	29569354	KJ	PLoS52	conceived and designed the study|performed data abstraction|contributed to data management|contributed to the critical appraisal of the manuscript|approved the final version of the manuscript	contributed to the critical appraisal of the manuscript	-	-	NO
5864576	29569354	KJ	PLoS52	conceived and designed the study|performed data abstraction|contributed to data management|contributed to the critical appraisal of the manuscript|approved the final version of the manuscript	approved the final version of the manuscript	-	-	NO
5864576	29569354	MG	PLoS52	conceived and designed the study|performed data abstraction|analysed the data|wrote the draft manuscript|contributed to the critical appraisal of the manuscript|approved the final version of the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5864576	29569354	MG	PLoS52	conceived and designed the study|performed data abstraction|analysed the data|wrote the draft manuscript|contributed to the critical appraisal of the manuscript|approved the final version of the manuscript	performed data abstraction	-	-	NO
5864576	29569354	MG	PLoS52	conceived and designed the study|performed data abstraction|analysed the data|wrote the draft manuscript|contributed to the critical appraisal of the manuscript|approved the final version of the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
5864576	29569354	MG	PLoS52	conceived and designed the study|performed data abstraction|analysed the data|wrote the draft manuscript|contributed to the critical appraisal of the manuscript|approved the final version of the manuscript	wrote the draft manuscript	Wrote the paper	Writing - Original Draft	YES
5864576	29569354	MG	PLoS52	conceived and designed the study|performed data abstraction|analysed the data|wrote the draft manuscript|contributed to the critical appraisal of the manuscript|approved the final version of the manuscript	contributed to the critical appraisal of the manuscript	-	-	NO
5864576	29569354	MG	PLoS52	conceived and designed the study|performed data abstraction|analysed the data|wrote the draft manuscript|contributed to the critical appraisal of the manuscript|approved the final version of the manuscript	approved the final version of the manuscript	-	-	NO
5864576	29569354	MW	PLoS52	conceived and designed the study|contributed to the critical appraisal of the manuscript|approved the final version of the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5864576	29569354	MW	PLoS52	conceived and designed the study|contributed to the critical appraisal of the manuscript|approved the final version of the manuscript	contributed to the critical appraisal of the manuscript	-	-	NO
5864576	29569354	MW	PLoS52	conceived and designed the study|contributed to the critical appraisal of the manuscript|approved the final version of the manuscript	approved the final version of the manuscript	-	-	NO
5864576	29569354	PC	PLoS52	conceived and designed the study|contributed to the critical appraisal of the manuscript|approved the final version of the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5864576	29569354	PC	PLoS52	conceived and designed the study|contributed to the critical appraisal of the manuscript|approved the final version of the manuscript	contributed to the critical appraisal of the manuscript	-	-	NO
5864576	29569354	PC	PLoS52	conceived and designed the study|contributed to the critical appraisal of the manuscript|approved the final version of the manuscript	approved the final version of the manuscript	-	-	NO
5613223	28983312	AL	2	were responsible for the overall design and conduct of experiments|conducted the seq data analysis|took the lead on manuscript development	were responsible for the overall design and conduct of experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5613223	28983312	AL	2	were responsible for the overall design and conduct of experiments|conducted the seq data analysis|took the lead on manuscript development	conducted the seq data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5613223	28983312	AL	2	were responsible for the overall design and conduct of experiments|conducted the seq data analysis|took the lead on manuscript development	took the lead on manuscript development	-	-	NO
5613223	28983312	CY	2	conducted the seq data analysis	conducted the seq data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5613223	28983312	DW	2	carried out the qrt-pcr and auxin content quantification	carried out the qrt-pcr and auxin content quantification	Performed the experiments	Investigation	YES
5613223	28983312	HC	2	carried out the qrt-pcr and auxin content quantification	carried out the qrt-pcr and auxin content quantification	Performed the experiments	Investigation	YES
5613223	28983312	JL	2	were responsible for the overall design and conduct of experiments|took the lead on manuscript development	were responsible for the overall design and conduct of experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5613223	28983312	JL	2	were responsible for the overall design and conduct of experiments|took the lead on manuscript development	took the lead on manuscript development	-	-	NO
5613223	28983312	MZ	2	were responsible for the overall design and conduct of experiments|prepared plant tissues and performed rna extraction and sequencing|took the lead on manuscript development	were responsible for the overall design and conduct of experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5613223	28983312	MZ	2	were responsible for the overall design and conduct of experiments|prepared plant tissues and performed rna extraction and sequencing|took the lead on manuscript development	prepared plant tissues and performed rna extraction and sequencing	Performed the experiments	Investigation	YES
5613223	28983312	MZ	2	were responsible for the overall design and conduct of experiments|prepared plant tissues and performed rna extraction and sequencing|took the lead on manuscript development	took the lead on manuscript development	-	-	NO
4409072	25909651	AK	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4409072	25909651	AK	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409072	25909651	AV	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409072	25909651	AV	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409072	25909651	EM	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409072	25909651	EM	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409072	25909651	GM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409072	25909651	GS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409072	25909651	JK	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409072	25909651	MG	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409072	25909651	MG	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409072	25909651	MG	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409072	25909651	MJK	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4409072	25909651	MJK	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409072	25909651	MK	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409072	25909651	MK	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409072	25909651	MK	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4538321	26339598	Nayeong Kim	2	contributed equally to this work	contributed equally to this work	-	-	NO
4538321	26339598	Soyeon Jeong	2	contributed equally to this work	contributed equally to this work	-	-	NO
3444955	22726667	CT	2	studies as radiological technologists|to the cardiac spect study and helped to draft the manuscript	studies as radiological technologists	-	-	NO
3444955	22726667	CT	2	studies as radiological technologists|to the cardiac spect study and helped to draft the manuscript	to the cardiac spect study and helped to draft the manuscript	Wrote the paper	Writing - Original Draft	YES
3444955	22726667	KF	2	participated as physicians	participated as physicians	-	-	NO
3444955	22726667	KaK	2	participated in the development of a respiratory motion indicator system and analysis of spect data	participated in the development of a respiratory motion indicator system and analysis of spect data	Performed the experiments|Analyzed the data	Formal analysis|Methodology	YES
3444955	22726667	KeK	2	participated as physicians	participated as physicians	-	-	NO
3444955	22726667	TM	2	participated in the discussion of spillover effects and misregistration effects between emission and attenuation data and helped to draft the manuscript	participated in the discussion of spillover effects and misregistration effects between emission and attenuation data and helped to draft the manuscript	Wrote the paper	Writing - Original Draft	YES
3444955	22726667	TZ	2	participated in the discussion of spillover effects and misregistration effects between emission and attenuation data and helped to draft the manuscript	participated in the discussion of spillover effects and misregistration effects between emission and attenuation data and helped to draft the manuscript	Wrote the paper	Writing - Original Draft	YES
3444955	22726667	YH	2	participated in the measurement of respiratory motions	participated in the measurement of respiratory motions	Performed the experiments	Investigation	YES
1762401	17183707	CC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762401	17183707	CC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762401	17183707	CC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762401	17183707	CM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762401	17183707	CM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762401	17183707	CM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762401	17183707	CU	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1762401	17183707	KG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1762401	17183707	SR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762401	17183707	SR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762401	17183707	SR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762401	17183707	SR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762401	17183707	SR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409105	25909503	CL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4409105	25909503	CL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409105	25909503	KW	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4409105	25909503	KW	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409105	25909503	LX	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409105	25909503	PY	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409105	25909503	QD	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409105	25909503	XL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409105	25909503	XL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409105	25909503	XL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409105	25909503	XL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409105	25909503	XW	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409105	25909503	XW	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5867275	29577598	All authors	2	revised the manuscript and approved the final version to be published	revised the manuscript and approved the final version to be published	Wrote the paper	Writing - Review & Editing	YES
5867275	29577598	BY	2	provided oversight for data collection	provided oversight for data collection	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources|Supervision	YES
5867275	29577598	CW	2	provided oversight for data collection	provided oversight for data collection	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources|Supervision	YES
5867275	29577598	DK	2	assisted in the data collection	assisted in the data collection	Performed the experiments	Investigation	YES
5867275	29577598	DW	2	provided oversight for data collection|assisted in the data collection	provided oversight for data collection	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources|Supervision	YES
5867275	29577598	DW	2	provided oversight for data collection|assisted in the data collection	assisted in the data collection	Performed the experiments	Investigation	YES
5867275	29577598	GM	2	assisted in the data collection	assisted in the data collection	Performed the experiments	Investigation	YES
5867275	29577598	JDT	2	contributed to the conception and design of the study	contributed to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5867275	29577598	JJO	2	contributed to the conception and design of the study|analysed the data and drafted the paper	contributed to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5867275	29577598	JJO	2	contributed to the conception and design of the study|analysed the data and drafted the paper	analysed the data and drafted the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5867275	29577598	LY	2	assisted in the data collection	assisted in the data collection	Performed the experiments	Investigation	YES
5867275	29577598	ML	2	assisted in the data collection	assisted in the data collection	Performed the experiments	Investigation	YES
5867275	29577598	ND	2	contributed to the conception and design of the study	contributed to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5867275	29577598	SH	2	assisted in the data collection	assisted in the data collection	Performed the experiments	Investigation	YES
5867275	29577598	WD	2	contributed to the conception and design of the study|analysed the data and drafted the paper	contributed to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5867275	29577598	WD	2	contributed to the conception and design of the study|analysed the data and drafted the paper	analysed the data and drafted the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5867275	29577598	WH	2	provided oversight for data collection|assisted in the data collection	provided oversight for data collection	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources|Supervision	YES
5867275	29577598	WH	2	provided oversight for data collection|assisted in the data collection	assisted in the data collection	Performed the experiments	Investigation	YES
5867275	29577598	WM	2	assisted in the data collection	assisted in the data collection	Performed the experiments	Investigation	YES
5423419	28330456	DMA	PLoS52	analyzed data and wrote the paper	analyzed data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5423419	28330456	HP	PLoS52	performed experiments, analyzed data and wrote the paper	performed experiments, analyzed data and wrote the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5423419	28330456	MWY	PLoS52	designed, performed the experiments, analyzed data and wrote the paper	designed, performed the experiments, analyzed data and wrote the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5423419	28330456	RS	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5423419	28330456	RY	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5423419	28330456	ZY	PLoS52	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5613247	28983313	FH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5613247	28983313	FH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
5613247	28983313	FH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5613247	28983313	FH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5613247	28983313	HZ	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5613247	28983313	HZ	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5613247	28983313	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5613247	28983313	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
5613247	28983313	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5613247	28983313	SH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5613247	28983313	SH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5613247	28983313	SH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5613247	28983313	SH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5613247	28983313	TN	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5613247	28983313	WC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5613247	28983313	XJ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5613247	28983313	YW	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5613247	28983313	YW	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5613247	28983313	YW	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3466153	22682066	ET	2	participated in the design of the study, helped with the statistical analysis and drafted the study	participated in the design of the study, helped with the statistical analysis and drafted the study	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3466153	22682066	LE	2	participated in the design of the study, helped with the statistical analysis and helped to draft the manuscript	participated in the design of the study, helped with the statistical analysis and helped to draft the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3466153	22682066	MO	2	participated in the design of the study and helped to draft the manuscript	participated in the design of the study and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3466153	22682066	MW	2	participated in the design of the study and helped to draft the manuscript	participated in the design of the study and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3466153	22682066	PH	2	performed the statistical analysis and helped to draft the manuscript	performed the statistical analysis and helped to draft the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
1762402	17183652	AA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762402	17183652	AA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762402	17183652	AA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762402	17183652	AA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762402	17183652	BA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762402	17183652	BA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762402	17183652	BA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762402	17183652	MC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1762402	17183652	PH	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762402	17183652	PH	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762402	17183652	SA	PLoS5	Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762402	17183652	SA	PLoS5	Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762402	17183652	SA	PLoS5	Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762402	17183652	SA	PLoS5	Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762402	17183652	TF	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409107	25910079	GT	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409107	25910079	KL	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409107	25910079	SJ	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409107	25910079	SJ	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409107	25910079	SJ	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5424310	28486930	HBC	2	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5424310	28486930	HNZ	2	designed the experiments|performed the experiments and sample collection|analyzed the data and drafted the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5424310	28486930	HNZ	2	designed the experiments|performed the experiments and sample collection|analyzed the data and drafted the manuscript	performed the experiments and sample collection	Performed the experiments	Investigation	YES
5424310	28486930	HNZ	2	designed the experiments|performed the experiments and sample collection|analyzed the data and drafted the manuscript	analyzed the data and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5424310	28486930	JYS	2	analyzed the data and drafted the manuscript	analyzed the data and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5424310	28486930	YZW	2	performed the experiments and sample collection	performed the experiments and sample collection	Performed the experiments	Investigation	YES
5867276	29577617	AG	PLoS52	conceived and designed the study|analysed the data|provided input on all manuscript drafts	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5867276	29577617	AG	PLoS52	conceived and designed the study|analysed the data|provided input on all manuscript drafts	analysed the data	Analyzed the data	Formal analysis	YES
5867276	29577617	AG	PLoS52	conceived and designed the study|analysed the data|provided input on all manuscript drafts	provided input on all manuscript drafts	Wrote the paper	Writing - Original Draft	YES
5867276	29577617	AP	PLoS52	conceived and designed the study|analysed the data|wrote the paper|provided input on all manuscript drafts	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5867276	29577617	AP	PLoS52	conceived and designed the study|analysed the data|wrote the paper|provided input on all manuscript drafts	analysed the data	Analyzed the data	Formal analysis	YES
5867276	29577617	AP	PLoS52	conceived and designed the study|analysed the data|wrote the paper|provided input on all manuscript drafts	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5867276	29577617	AP	PLoS52	conceived and designed the study|analysed the data|wrote the paper|provided input on all manuscript drafts	provided input on all manuscript drafts	Wrote the paper	Writing - Original Draft	YES
5867276	29577617	HN	PLoS52	conceived and designed the study|managed data collection|provided input on all manuscript drafts	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5867276	29577617	HN	PLoS52	conceived and designed the study|managed data collection|provided input on all manuscript drafts	managed data collection	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5867276	29577617	HN	PLoS52	conceived and designed the study|managed data collection|provided input on all manuscript drafts	provided input on all manuscript drafts	Wrote the paper	Writing - Original Draft	YES
5867276	29577617	MM	PLoS52	conceived and designed the study|analysed the data|provided input on all manuscript drafts	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5867276	29577617	MM	PLoS52	conceived and designed the study|analysed the data|provided input on all manuscript drafts	analysed the data	Analyzed the data	Formal analysis	YES
5867276	29577617	MM	PLoS52	conceived and designed the study|analysed the data|provided input on all manuscript drafts	provided input on all manuscript drafts	Wrote the paper	Writing - Original Draft	YES
5867276	29577617	MR	PLoS52	conceived and designed the study|analysed the data|wrote the paper|provided input on all manuscript drafts	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5867276	29577617	MR	PLoS52	conceived and designed the study|analysed the data|wrote the paper|provided input on all manuscript drafts	analysed the data	Analyzed the data	Formal analysis	YES
5867276	29577617	MR	PLoS52	conceived and designed the study|analysed the data|wrote the paper|provided input on all manuscript drafts	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5867276	29577617	MR	PLoS52	conceived and designed the study|analysed the data|wrote the paper|provided input on all manuscript drafts	provided input on all manuscript drafts	Wrote the paper	Writing - Original Draft	YES
5867276	29577617	PB	PLoS52	managed data collection|provided input on all manuscript drafts	managed data collection	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5867276	29577617	PB	PLoS52	managed data collection|provided input on all manuscript drafts	provided input on all manuscript drafts	Wrote the paper	Writing - Original Draft	YES
5867276	29577617	RB	PLoS52	provided input on all manuscript drafts	provided input on all manuscript drafts	Wrote the paper	Writing - Original Draft	YES
5867276	29577617	SS	PLoS52	managed data collection|provided input on all manuscript drafts	managed data collection	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5867276	29577617	SS	PLoS52	managed data collection|provided input on all manuscript drafts	provided input on all manuscript drafts	Wrote the paper	Writing - Original Draft	YES
5867276	29577617	VO	PLoS52	provided input on all manuscript drafts	provided input on all manuscript drafts	Wrote the paper	Writing - Original Draft	YES
5867276	29577617	WE	PLoS52	conceived and designed the study|analysed the data|provided input on all manuscript drafts	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5867276	29577617	WE	PLoS52	conceived and designed the study|analysed the data|provided input on all manuscript drafts	analysed the data	Analyzed the data	Formal analysis	YES
5867276	29577617	WE	PLoS52	conceived and designed the study|analysed the data|provided input on all manuscript drafts	provided input on all manuscript drafts	Wrote the paper	Writing - Original Draft	YES
5613731	28983302	All authors	2	read and approved the final manuscript for publication	read and approved the final manuscript for publication	Wrote the paper	Writing - Review & Editing	YES
5613731	28983302	DL	2	proposed the idea and hypothesis	proposed the idea and hypothesis	Conceived and designed the experiments	Conceptualization	YES
5613731	28983302	PC	2	proposed the idea and hypothesis|drafted the manuscript	proposed the idea and hypothesis	Conceived and designed the experiments	Conceptualization	YES
5613731	28983302	PC	2	proposed the idea and hypothesis|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5613731	28983302	TL	2	performed the statistical analysis and helped to draft and revise the manuscript	performed the statistical analysis and helped to draft and revise the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
1762403	17183688	YP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762403	17183688	YP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762403	17183688	YP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762403	17183688	YP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3467189	22877315	AK	2	provided very valuable intellectual advice on rodent anaesthesia and critically edited and reviewed the manuscript	provided very valuable intellectual advice on rodent anaesthesia and critically edited and reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
3467189	22877315	JLT	2	performed some of the reported animal experiments, reviewed current literature, provided the concept for the review and wrote the manuscript	performed some of the reported animal experiments, reviewed current literature, provided the concept for the review and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
3467189	22877315	WG	2	reviewed the manuscript and supported the conception of this review	reviewed the manuscript and supported the conception of this review	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
4409109	25909648	AA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409109	25909648	AA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409109	25909648	AA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409109	25909648	AA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409109	25909648	AA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409109	25909648	EG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409109	25909648	EG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409109	25909648	EG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409109	25909648	EG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409109	25909648	MG	PLoS5	Did experiments with the polarized light and studied the effect of impurities on the glass surface	Did experiments with the polarized light and studied the effect of impurities on the glass surface	Performed the experiments	Investigation	YES
5867332	29577616	A.C.	2	contributed to study concept and design|contributed to data retrieval, analysis, or interpretation|contributed to manuscript preparation	contributed to study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5867332	29577616	A.C.	2	contributed to study concept and design|contributed to data retrieval, analysis, or interpretation|contributed to manuscript preparation	contributed to data retrieval, analysis, or interpretation	Analyzed the data	Formal analysis	YES
5867332	29577616	A.C.	2	contributed to study concept and design|contributed to data retrieval, analysis, or interpretation|contributed to manuscript preparation	contributed to manuscript preparation	Wrote the paper	Writing - Original Draft	YES
5867332	29577616	All authors	2	provided critical review and edits	provided critical review and edits	Wrote the paper	Writing - Review & Editing	YES
5867332	29577616	D.V.	2	contributed to data retrieval, analysis, or interpretation	contributed to data retrieval, analysis, or interpretation	Analyzed the data	Formal analysis	YES
5867332	29577616	D.V.G.	2	contributed to data retrieval, analysis, or interpretation	contributed to data retrieval, analysis, or interpretation	Analyzed the data	Formal analysis	YES
5867332	29577616	J.C.H.	2	contributed to study concept and design|contributed to data retrieval, analysis, or interpretation|contributed to manuscript preparation	contributed to study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5867332	29577616	J.C.H.	2	contributed to study concept and design|contributed to data retrieval, analysis, or interpretation|contributed to manuscript preparation	contributed to data retrieval, analysis, or interpretation	Analyzed the data	Formal analysis	YES
5867332	29577616	J.C.H.	2	contributed to study concept and design|contributed to data retrieval, analysis, or interpretation|contributed to manuscript preparation	contributed to manuscript preparation	Wrote the paper	Writing - Original Draft	YES
5867332	29577616	K.R.M.	2	contributed to study concept and design	contributed to study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5867332	29577616	M.M.	2	contributed to data retrieval, analysis, or interpretation	contributed to data retrieval, analysis, or interpretation	Analyzed the data	Formal analysis	YES
5867332	29577616	R.H.	2	contributed to data retrieval, analysis, or interpretation	contributed to data retrieval, analysis, or interpretation	Analyzed the data	Formal analysis	YES
5867332	29577616	R.M.G.	2	contributed to data retrieval, analysis, or interpretation	contributed to data retrieval, analysis, or interpretation	Analyzed the data	Formal analysis	YES
5424319	28486986	RP	2	conceived and designed the study|wrote the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5424319	28486986	RP	2	conceived and designed the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5424319	28486986	YH	2	conceived and designed the study|performed the analysis|wrote the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5424319	28486986	YH	2	conceived and designed the study|performed the analysis|wrote the manuscript	performed the analysis	Performed the experiments	Investigation	YES
5424319	28486986	YH	2	conceived and designed the study|performed the analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3468361	22682364	AMS	2	participated in the design of the molecular imaging components of the study and coordination of molecular imaging data acquisition and analysis	participated in the design of the molecular imaging components of the study and coordination of molecular imaging data acquisition and analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology|Project administration|Visualization	YES
3468361	22682364	All authors	2	were involved in the drafting of the manuscript and approved the final version for submission	were involved in the drafting of the manuscript and approved the final version for submission	Wrote the paper	Writing - Original Draft	YES
3468361	22682364	CB	2	was responsible for the clinical development of sunitinib and was therefore involved in the conception, design, and execution of the study, and data evaluation	was responsible for the clinical development of sunitinib and was therefore involved in the conception, design, and execution of the study, and data evaluation	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
3468361	22682364	GCT	2	was involved in the conception of the project, protocol writing, patient accrual, and data analysis	was involved in the conception of the project, protocol writing, patient accrual, and data analysis	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology	YES
3468361	22682364	GOK	2	was involved in the design of the imaging studies and data analysis	was involved in the design of the imaging studies and data analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology|Visualization	YES
3468361	22682364	NB	2	was involved in conceiving of the study and participated in the study design and coordination	was involved in conceiving of the study and participated in the study design and coordination	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
3468361	22682364	PLM	2	participated in the design and coordination of the study, and analysis	participated in the design and coordination of the study, and analysis	Conceived and designed the experiments	Methodology|Project administration	YES
3468361	22682364	RJH	2	was involved in the conception and design of the molecular imaging components of the clinical trial of which this study represents a subgroup	was involved in the conception and design of the molecular imaging components of the clinical trial of which this study represents a subgroup	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Investigation|Methodology|Visualization	YES
3468361	22682364	TJM	2	reviewed the data and the manuscript	reviewed the data and the manuscript	Wrote the paper	Writing - Review & Editing	YES
3468361	22682364	TS	2	performed the pet data collection and image analysis	performed the pet data collection and image analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
1762404	17205127	DR	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762404	17205127	DR	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762404	17205127	LP	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762404	17205127	LP	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762404	17205127	LP	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762404	17205127	MT	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1762404	17205127	OL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1762404	17205127	OL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762404	17205127	TK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762404	17205127	TK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762404	17205127	TK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762404	17205127	TK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5613732	28983310	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5613732	28983310	BY	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5613732	28983310	FL	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5613732	28983310	HM	PLoS52	contributed to editing the manuscript	contributed to editing the manuscript	Wrote the paper	Writing - Review & Editing	YES
5613732	28983310	JZ	PLoS52	prepared the samples for sequencing	prepared the samples for sequencing	Performed the experiments	Investigation	YES
5613732	28983310	JpZ	PLoS52	prepared the samples for sequencing	prepared the samples for sequencing	Performed the experiments	Investigation	YES
5613732	28983310	LL	PLoS52	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5613732	28983310	SZ	PLoS52	designed the study|conducted the bioinformatics analyses and wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5613732	28983310	SZ	PLoS52	designed the study|conducted the bioinformatics analyses and wrote the manuscript	conducted the bioinformatics analyses and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5613732	28983310	WL	PLoS52	contributed to editing the manuscript	contributed to editing the manuscript	Wrote the paper	Writing - Review & Editing	YES
5613732	28983310	XL	PLoS52	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5613732	28983310	XY	PLoS52	prepared the samples for sequencing	prepared the samples for sequencing	Performed the experiments	Investigation	YES
5613732	28983310	XqL	PLoS52	prepared the samples for sequencing	prepared the samples for sequencing	Performed the experiments	Investigation	YES
5613732	28983310	YL	PLoS52	contributed to editing the manuscript	contributed to editing the manuscript	Wrote the paper	Writing - Review & Editing	YES
3469367	22925467	AS	2	conceived of the study, participated in its design and coordination and in the measurements, and drafted the manuscript	conceived of the study, participated in its design and coordination and in the measurements, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Project administration|Writing - Original Draft	YES
3469367	22925467	CB	2	participated in the study design and coordination and in the measurements, and helped draft the manuscript	participated in the study design and coordination and in the measurements, and helped draft the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Project administration|Writing - Original Draft	YES
3469367	22925467	DN	2	carried out all measurements and data processing, and helped draft the manuscript	carried out all measurements and data processing, and helped draft the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Investigation|Writing - Original Draft	YES
4409110	25910259	AP	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409110	25910259	AP	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409110	25910259	LC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409110	25910259	LC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409110	25910259	LC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409110	25910259	NN	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409110	25910259	NN	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409110	25910259	NN	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409110	25910259	NN	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409110	25910259	NW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409110	25910259	NW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409110	25910259	NW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409110	25910259	TB	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409110	25910259	TB	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5424326	28486968	ADV	2	designed the main aims of this work|provided guidance in the drafting of the manuscript	designed the main aims of this work	Conceived and designed the experiments	-	YES
5424326	28486968	ADV	2	designed the main aims of this work|provided guidance in the drafting of the manuscript	provided guidance in the drafting of the manuscript	Wrote the paper	Supervision|Writing - Original Draft	YES
5424326	28486968	All authors	2	read, corrected and approved the final manuscript	read, corrected and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5424326	28486968	FMC	2	designed the main aims of this work|conducted the different bioinformatic approaches to carry out the comparative genomics|provided guidance in the drafting of the manuscript	designed the main aims of this work	Conceived and designed the experiments	-	YES
5424326	28486968	FMC	2	designed the main aims of this work|conducted the different bioinformatic approaches to carry out the comparative genomics|provided guidance in the drafting of the manuscript	conducted the different bioinformatic approaches to carry out the comparative genomics	Performed the experiments	Formal analysis|Investigation	YES
5424326	28486968	FMC	2	designed the main aims of this work|conducted the different bioinformatic approaches to carry out the comparative genomics|provided guidance in the drafting of the manuscript	provided guidance in the drafting of the manuscript	Wrote the paper	Supervision|Writing - Original Draft	YES
5424326	28486968	GWS	2	designed the main aims of this work|wrote the manuscript|provided guidance in the drafting of the manuscript	designed the main aims of this work	Conceived and designed the experiments	-	YES
5424326	28486968	GWS	2	designed the main aims of this work|wrote the manuscript|provided guidance in the drafting of the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5424326	28486968	GWS	2	designed the main aims of this work|wrote the manuscript|provided guidance in the drafting of the manuscript	provided guidance in the drafting of the manuscript	Wrote the paper	Supervision|Writing - Original Draft	YES
5424326	28486968	JAGB	2	designed the main aims of this work|performed plasmid dna isolation and purification, and the different molecular biology techniques used in this study|conducted the different bioinformatic approaches to carry out the comparative genomics|wrote the manuscript	designed the main aims of this work	Conceived and designed the experiments	-	YES
5424326	28486968	JAGB	2	designed the main aims of this work|performed plasmid dna isolation and purification, and the different molecular biology techniques used in this study|conducted the different bioinformatic approaches to carry out the comparative genomics|wrote the manuscript	performed plasmid dna isolation and purification, and the different molecular biology techniques used in this study	Performed the experiments	Investigation	YES
5424326	28486968	JAGB	2	designed the main aims of this work|performed plasmid dna isolation and purification, and the different molecular biology techniques used in this study|conducted the different bioinformatic approaches to carry out the comparative genomics|wrote the manuscript	conducted the different bioinformatic approaches to carry out the comparative genomics	Performed the experiments	Formal analysis|Investigation	YES
5424326	28486968	JAGB	2	designed the main aims of this work|performed plasmid dna isolation and purification, and the different molecular biology techniques used in this study|conducted the different bioinformatic approaches to carry out the comparative genomics|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5867334	29577623	GM	2	contributed to the conception of the study, conceived and generated simulations, conducted analyses and wrote the first draft of the manuscript	contributed to the conception of the study, conceived and generated simulations, conducted analyses and wrote the first draft of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
5867334	29577623	HAW	2	contributed to the conception and design of the study	contributed to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5867334	29577623	LJA	2	conceived the study and simulations, and contributed to analyses	conceived the study and simulations, and contributed to analyses	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
5867334	29577623	SFA	2	contributed to the coding and simulations	contributed to the coding and simulations	-	Formal analysis	YES
1762405	17183645	IG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762405	17183645	IG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762405	17183645	IG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762405	17183645	JR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762405	17183645	JR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762405	17183645	JR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762405	17183645	JR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762405	17183645	SP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762405	17183645	SP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762405	17183645	SP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5614975	29018465	CZ	2	generated trangenic plants	generated trangenic plants	Performed the experiments	Investigation	YES
5614975	29018465	JC	2	cloned cdsamdc1 from bermudagrass	cloned cdsamdc1 from bermudagrass	Performed the experiments	Investigation	YES
5614975	29018465	JL	2	conducted most of the experiments of transgenic centipedegrass	conducted most of the experiments of transgenic centipedegrass	Performed the experiments	Investigation	YES
5614975	29018465	ML	2	conducted most of the experiments of transgenic centipedegrass	conducted most of the experiments of transgenic centipedegrass	Performed the experiments	Investigation	YES
5614975	29018465	PZ	2	determined gene expression in bermudagrass	determined gene expression in bermudagrass	Performed the experiments	Investigation	YES
5614975	29018465	SL	2	designed experiments and wrote manuscript	designed experiments and wrote manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5614975	29018465	ZG	2	designed experiments and wrote manuscript	designed experiments and wrote manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3472173	22788874	AC	2	conceived and designed the study, analysed and interpreted the data, drafted, wrote, and revised the manuscript, is the guarantor of the integrity of the study, and approved the final version to be published	conceived and designed the study, analysed and interpreted the data, drafted, wrote, and revised the manuscript, is the guarantor of the integrity of the study, and approved the final version to be published	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Data curation|Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
3472173	22788874	BAM	2	recruited patients and revised the manuscript	recruited patients and revised the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
3472173	22788874	BS	2	has done the statistics and revised the manuscript	has done the statistics and revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
3472173	22788874	CWAP	2	conceived and designed, read out, and revised the manuscript	conceived and designed, read out, and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
3472173	22788874	DRF	2	conceived and designed the study, read out, acquired, analysed, and interpreted the data, and drafted, wrote, and revised the manuscript	conceived and designed the study, read out, acquired, analysed, and interpreted the data, and drafted, wrote, and revised the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
3472173	22788874	GT	2	recruited patients and revised the manuscript	recruited patients and revised the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
3472173	22788874	GvS	2	acquired the irb approval and revised the manuscript	acquired the irb approval and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
3472173	22788874	KDMS	2	read out and revised the manuscript	read out and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
3472173	22788874	KS	2	acquired the irb approval, recruited patients, and revised the manuscript	acquired the irb approval, recruited patients, and revised the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
3472173	22788874	VZ	2	read out, wrote, and revised the manuscript	read out, wrote, and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4409111	25909476	HYH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409111	25909476	HYH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409111	25909476	HYH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409111	25909476	HYH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409111	25909476	STT	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4409111	25909476	STT	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409111	25909476	WC	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409111	25909476	WC	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409111	25909476	WC	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409111	25909476	WC	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409111	25909476	XLJ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409111	25909476	ZH	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4409111	25909476	ZH	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5424422	28486948	H-HZ	2	revised the whole manuscript	revised the whole manuscript	Wrote the paper	Writing - Review & Editing	YES
5424422	28486948	RL	2	designed the study, analyzed the data, wrote the paper and final approval of the version to be published	designed the study, analyzed the data, wrote the paper and final approval of the version to be published	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5424422	28486948	WZ	2	revised the whole manuscript	revised the whole manuscript	Wrote the paper	Writing - Review & Editing	YES
5424422	28486948	Z-QL	2	revised the whole manuscript	revised the whole manuscript	Wrote the paper	Writing - Review & Editing	YES
5614976	29018457	All authors	2	drafted the manuscript|gave final approval for publication	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5614976	29018457	All authors	2	drafted the manuscript|gave final approval for publication	gave final approval for publication	-	-	NO
5614976	29018457	FG	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5614976	29018457	GB	2	implemented the analyses	implemented the analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5614976	29018457	JC	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5614976	29018457	ND	2	implemented the analyses	implemented the analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5614976	29018457	TL	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5614976	29018457	XT	2	designed the study|implemented the analyses	designed the study	Conceived and designed the experiments	Methodology	YES
5614976	29018457	XT	2	designed the study|implemented the analyses	implemented the analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5614976	29018457	XY	2	implemented the analyses	implemented the analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5876496	29600595	AM	2	is the co-principal investigator and contributed to the studys design and implementation	is the co-principal investigator and contributed to the studys design and implementation	Conceived and designed the experiments|Performed the experiments	Conceptualization|Funding acquisition|Investigation|Methodology	YES
5876496	29600595	All authors	2	have reviewed and contributed to the writing, and have read and approve the final manuscript	have reviewed and contributed to the writing, and have read and approve the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5876496	29600595	AvdS	2	is the principal investigator and contributed to the studys design, implementation, analysis and led the writing of this manuscript	is the principal investigator and contributed to the studys design, implementation, analysis and led the writing of this manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Funding acquisition|Investigation|Methodology|Writing - Original Draft	YES
5876496	29600595	EB	2	is the study statistician and contributed to data management, analysis and writing of this manuscript	is the study statistician and contributed to data management, analysis and writing of this manuscript	Analyzed the data|Wrote the paper	Data curation|Formal analysis|Writing - Original Draft	YES
5876496	29600595	FO	2	are the site study coordinators and contributed to study implementation and data collection	are the site study coordinators and contributed to study implementation and data collection	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Project administration|Resources	YES
5876496	29600595	JS	2	is the medical monitor and contributed to clinical aspects of the study	is the medical monitor and contributed to clinical aspects of the study	-	Supervision	YES
5876496	29600595	KA	2	are the site principal investigators and led the implementation and data collection|are the site principal investigators and led the implementation and data collection	are the site principal investigators and led the implementation and data collection	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Funding acquisition|Investigation	YES
5876496	29600595	KA	2	are the site principal investigators and led the implementation and data collection|are the site principal investigators and led the implementation and data collection	are the site principal investigators and led the implementation and data collection	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Funding acquisition|Investigation	YES
5876496	29600595	KM	2	are the site study coordinators and contributed to study implementation and data collection	are the site study coordinators and contributed to study implementation and data collection	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Project administration|Resources	YES
5876496	29600595	RW	2	is the study coordinator and contributed to the studys design and implementation and to writing of this manuscript	is the study coordinator and contributed to the studys design and implementation and to writing of this manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Project administration|Writing - Original Draft	YES
1762406	17183653	AS	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762406	17183653	HN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762406	17183653	HN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762406	17183653	HN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762406	17183653	MC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1762406	17183653	MK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762406	17183653	MK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762406	17183653	MK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762406	17183653	RM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762406	17183653	RM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762406	17183653	RM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762406	17183653	RM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762406	17183653	SM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1762406	17183653	SO	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
3472222	22738240	AB	2	undertook the treatment validation work presented in additional file 2	undertook the treatment validation work presented in additional file 2	Performed the experiments	Investigation|Validation	YES
3472222	22738240	JEF	2	helped with the pet experiments and image analysis, and undertook the data curation and mining, statistical analysis, and figure preparation	helped with the pet experiments and image analysis, and undertook the data curation and mining, statistical analysis, and figure preparation	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation|Visualization	YES
3472222	22738240	RP	2	critically reviewed the data analysis, figures, and manuscript	critically reviewed the data analysis, figures, and manuscript	Analyzed the data|Wrote the paper	Formal analysis|Visualization|Writing - Review & Editing	YES
3472222	22738240	SPW	2	initiated and directed the work and wrote the manuscript	initiated and directed the work and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Supervision|Writing - Original Draft	YES
3472222	22738240	TB	2	oversaw the statistical analysis, ran the simulations, and prepared the mathematical analysis of additional file 3	oversaw the statistical analysis, ran the simulations, and prepared the mathematical analysis of additional file 3	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Supervision	YES
4409114	25909454	AMV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409114	25909454	AMV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409114	25909454	AMV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409114	25909454	AMV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409114	25909454	AMV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409114	25909454	DSM	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409114	25909454	DSM	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409114	25909454	KL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409114	25909454	KL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409114	25909454	KL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409114	25909454	MM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409114	25909454	MM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409114	25909454	MM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409114	25909454	NBR	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409114	25909454	NBR	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409114	25909454	NBR	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409114	25909454	RVS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409114	25909454	RVS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409114	25909454	RVS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409114	25909454	SV	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409114	25909454	SV	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409114	25909454	SV	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5878412	29603887	ADH	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5878412	29603887	AJ	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5878412	29603887	AMP	2	designed the survey|performed the data analysis and interpretation and drafted the manuscript	designed the survey	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5878412	29603887	AMP	2	designed the survey|performed the data analysis and interpretation and drafted the manuscript	performed the data analysis and interpretation and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5878412	29603887	AP	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5878412	29603887	CB	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5878412	29603887	CM	2	designed the survey|coordinated data collection|revised the manuscript	designed the survey	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5878412	29603887	CM	2	designed the survey|coordinated data collection|revised the manuscript	coordinated data collection	Performed the experiments	Investigation|Project administration	YES
5878412	29603887	CM	2	designed the survey|coordinated data collection|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5878412	29603887	CWW	2	designed the survey|coordinated data collection|revised the manuscript	designed the survey	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5878412	29603887	CWW	2	designed the survey|coordinated data collection|revised the manuscript	coordinated data collection	Performed the experiments	Investigation|Project administration	YES
5878412	29603887	CWW	2	designed the survey|coordinated data collection|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5878412	29603887	DN	2	designed the survey|coordinated data collection|revised the manuscript	designed the survey	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5878412	29603887	DN	2	designed the survey|coordinated data collection|revised the manuscript	coordinated data collection	Performed the experiments	Investigation|Project administration	YES
5878412	29603887	DN	2	designed the survey|coordinated data collection|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5878412	29603887	EY	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5878412	29603887	FN	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5878412	29603887	KA	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5878412	29603887	SND	2	designed the survey|coordinated data collection|revised the manuscript	designed the survey	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5878412	29603887	SND	2	designed the survey|coordinated data collection|revised the manuscript	coordinated data collection	Performed the experiments	Investigation|Project administration	YES
5878412	29603887	SND	2	designed the survey|coordinated data collection|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
3472282	23014191	AV	2	assisted in the design of the data analysis and revised the manuscript	assisted in the design of the data analysis and revised the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
3472282	23014191	CH	2	participated in the design and interpretation of the study and have critically revised the manuscript	participated in the design and interpretation of the study and have critically revised the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
3472282	23014191	CW	2	assisted in the design of the data analysis and revised the manuscript	assisted in the design of the data analysis and revised the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
3472282	23014191	KR	2	has made substantial contributions to the conception and design of the study and to the analysis and interpretation of data and drafted the manuscript	has made substantial contributions to the conception and design of the study and to the analysis and interpretation of data and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Methodology|Resources|Writing - Original Draft	YES
3472282	23014191	MCB	2	participated in the design and interpretation of the study and have critically revised the manuscript	participated in the design and interpretation of the study and have critically revised the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
3472282	23014191	MW	2	have conceived the study, participated in its interpretation, and have critically revised the manuscript	have conceived the study, participated in its interpretation, and have critically revised the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Review & Editing	YES
3472282	23014191	OS	2	have conceived the study, participated in its interpretation, and have critically revised the manuscript	have conceived the study, participated in its interpretation, and have critically revised the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Review & Editing	YES
1762407	17183722	CW	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762407	17183722	HD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762407	17183722	HD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762407	17183722	HD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762407	17183722	HD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762407	17183722	MT	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762407	17183722	MT	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762407	17183722	MT	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762407	17183722	NK	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762407	17183722	NK	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762407	17183722	TK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762407	17183722	TK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762407	17183722	TK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762407	17183722	TK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762407	17183722	TK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5614988	29018460	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5614988	29018460	FS	PLoS52	designed and organized the entire project|revised it	designed and organized the entire project	Conceived and designed the experiments	Methodology|Project administration	YES
5614988	29018460	FS	PLoS52	designed and organized the entire project|revised it	revised it	Wrote the paper	Writing - Review & Editing	YES
5614988	29018460	MD	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5614988	29018460	The authors	PLoS52	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	Performed the experiments	Investigation	YES
5614988	29018460	WY	PLoS52	designed and organized the entire project|performed the experiments	designed and organized the entire project	Conceived and designed the experiments	Methodology|Project administration	YES
5614988	29018460	WY	PLoS52	designed and organized the entire project|performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5614988	29018460	YjH	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5614988	29018460	YxH	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5425981	28490319	PZ	2	conceived and designed the experiment|analyzed and interpreted the data|wrote the manuscript	conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5425981	28490319	PZ	2	conceived and designed the experiment|analyzed and interpreted the data|wrote the manuscript	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5425981	28490319	PZ	2	conceived and designed the experiment|analyzed and interpreted the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5425981	28490319	SH	2	conceived and designed the experiment|wrote the manuscript	conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5425981	28490319	SH	2	conceived and designed the experiment|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5425981	28490319	XZ	2	conceived and designed the experiment	conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409115	25909654	BTD	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409115	25909654	BTD	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409115	25909654	EWP	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409115	25909654	EWP	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409115	25909654	EWP	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409115	25909654	EWP	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409115	25909654	MJT	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409115	25909654	MJT	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409115	25909654	MJT	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409115	25909654	MJT	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409115	25909654	PAS	PLoS5	Conceived and designed the experiments|Recruited participants|Behavioural and clinical assessments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409115	25909654	PAS	PLoS5	Conceived and designed the experiments|Recruited participants|Behavioural and clinical assessments	Recruited participants	Performed the experiments	Investigation	YES
4409115	25909654	PAS	PLoS5	Conceived and designed the experiments|Recruited participants|Behavioural and clinical assessments	Behavioural and clinical assessments	-	-	NO
4409115	25909654	PNS	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409115	25909654	PNS	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409115	25909654	RJ	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409115	25909654	RJG	PLoS5	Conceived and designed the experiments|Recruited participants|Behavioural and clinical assessments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409115	25909654	RJG	PLoS5	Conceived and designed the experiments|Recruited participants|Behavioural and clinical assessments	Recruited participants	Performed the experiments	Investigation	YES
4409115	25909654	RJG	PLoS5	Conceived and designed the experiments|Recruited participants|Behavioural and clinical assessments	Behavioural and clinical assessments	-	-	NO
4409115	25909654	SMD	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409115	25909654	SMD	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409115	25909654	SMD	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3475087	23016793	AKB	2	supervised the study and the assessments and directed the focus of the research	supervised the study and the assessments and directed the focus of the research	-	Supervision	YES
3475087	23016793	CL	2	analyzed the image data as well as clinical data and corrected the manuscript	analyzed the image data as well as clinical data and corrected the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Visualization|Writing - Review & Editing	YES
3475087	23016793	II	2	synthesized the radiotracer	synthesized the radiotracer	Performed the experiments	Investigation	YES
3475087	23016793	MCK	2	conceived of the study and study layout, performed the image analysis, and corrected and revised the manuscript	conceived of the study and study layout, performed the image analysis, and corrected and revised the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Investigation|Visualization|Writing - Review & Editing	YES
3475087	23016793	SS	2	supervised the work and gave input to the manuscript	supervised the work and gave input to the manuscript	-	Supervision	YES
3475087	23016793	WB	2	supervised the research area	supervised the research area	-	Supervision	YES
3475087	23016793	XL	2	conducted the study, analyzed the data, and wrote the manuscript	conducted the study, analyzed the data, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5878413	29603900	AH	2	contributed to study concept and design|contributed to critical revision of the manuscript	contributed to study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5878413	29603900	AH	2	contributed to study concept and design|contributed to critical revision of the manuscript	contributed to critical revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5878413	29603900	EH	2	contributed to study concept and design|contributed to acquisition, analysis or interpretation of the data|contributed to drafting of the manuscript|contributed to critical revision of the manuscript|obtained funding	contributed to study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5878413	29603900	EH	2	contributed to study concept and design|contributed to acquisition, analysis or interpretation of the data|contributed to drafting of the manuscript|contributed to critical revision of the manuscript|obtained funding	contributed to acquisition, analysis or interpretation of the data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5878413	29603900	EH	2	contributed to study concept and design|contributed to acquisition, analysis or interpretation of the data|contributed to drafting of the manuscript|contributed to critical revision of the manuscript|obtained funding	contributed to drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
5878413	29603900	EH	2	contributed to study concept and design|contributed to acquisition, analysis or interpretation of the data|contributed to drafting of the manuscript|contributed to critical revision of the manuscript|obtained funding	contributed to critical revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5878413	29603900	EH	2	contributed to study concept and design|contributed to acquisition, analysis or interpretation of the data|contributed to drafting of the manuscript|contributed to critical revision of the manuscript|obtained funding	obtained funding	-	Funding acquisition	YES
5878413	29603900	GS	2	contributed to study concept and design|contributed to critical revision of the manuscript	contributed to study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5878413	29603900	GS	2	contributed to study concept and design|contributed to critical revision of the manuscript	contributed to critical revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5878413	29603900	HdV	2	contributed to study concept and design|contributed to acquisition, analysis or interpretation of the data|contributed to critical revision of the manuscript	contributed to study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5878413	29603900	HdV	2	contributed to study concept and design|contributed to acquisition, analysis or interpretation of the data|contributed to critical revision of the manuscript	contributed to acquisition, analysis or interpretation of the data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5878413	29603900	HdV	2	contributed to study concept and design|contributed to acquisition, analysis or interpretation of the data|contributed to critical revision of the manuscript	contributed to critical revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5878413	29603900	JvdH	2	contributed to study concept and design|contributed to acquisition, analysis or interpretation of the data|contributed to critical revision of the manuscript|contributed to statistical analysis	contributed to study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5878413	29603900	JvdH	2	contributed to study concept and design|contributed to acquisition, analysis or interpretation of the data|contributed to critical revision of the manuscript|contributed to statistical analysis	contributed to acquisition, analysis or interpretation of the data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5878413	29603900	JvdH	2	contributed to study concept and design|contributed to acquisition, analysis or interpretation of the data|contributed to critical revision of the manuscript|contributed to statistical analysis	contributed to critical revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5878413	29603900	JvdH	2	contributed to study concept and design|contributed to acquisition, analysis or interpretation of the data|contributed to critical revision of the manuscript|contributed to statistical analysis	contributed to statistical analysis	Analyzed the data	Formal analysis	YES
5878413	29603900	MP	2	contributed to study concept and design|contributed to acquisition, analysis or interpretation of the data|contributed to critical revision of the manuscript|obtained funding	contributed to study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5878413	29603900	MP	2	contributed to study concept and design|contributed to acquisition, analysis or interpretation of the data|contributed to critical revision of the manuscript|obtained funding	contributed to acquisition, analysis or interpretation of the data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5878413	29603900	MP	2	contributed to study concept and design|contributed to acquisition, analysis or interpretation of the data|contributed to critical revision of the manuscript|obtained funding	contributed to critical revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5878413	29603900	MP	2	contributed to study concept and design|contributed to acquisition, analysis or interpretation of the data|contributed to critical revision of the manuscript|obtained funding	obtained funding	-	Funding acquisition	YES
5878413	29603900	MSvdL	2	contributed to study concept and design|contributed to acquisition, analysis or interpretation of the data|contributed to critical revision of the manuscript|contributed to statistical analysis|obtained funding	contributed to study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5878413	29603900	MSvdL	2	contributed to study concept and design|contributed to acquisition, analysis or interpretation of the data|contributed to critical revision of the manuscript|contributed to statistical analysis|obtained funding	contributed to acquisition, analysis or interpretation of the data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5878413	29603900	MSvdL	2	contributed to study concept and design|contributed to acquisition, analysis or interpretation of the data|contributed to critical revision of the manuscript|contributed to statistical analysis|obtained funding	contributed to critical revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5878413	29603900	MSvdL	2	contributed to study concept and design|contributed to acquisition, analysis or interpretation of the data|contributed to critical revision of the manuscript|contributed to statistical analysis|obtained funding	contributed to statistical analysis	Analyzed the data	Formal analysis	YES
5878413	29603900	MSvdL	2	contributed to study concept and design|contributed to acquisition, analysis or interpretation of the data|contributed to critical revision of the manuscript|contributed to statistical analysis|obtained funding	obtained funding	-	Funding acquisition	YES
5878413	29603900	RA	2	contributed to study concept and design|contributed to acquisition, analysis or interpretation of the data|contributed to drafting of the manuscript|contributed to critical revision of the manuscript|contributed to statistical analysis	contributed to study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5878413	29603900	RA	2	contributed to study concept and design|contributed to acquisition, analysis or interpretation of the data|contributed to drafting of the manuscript|contributed to critical revision of the manuscript|contributed to statistical analysis	contributed to acquisition, analysis or interpretation of the data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5878413	29603900	RA	2	contributed to study concept and design|contributed to acquisition, analysis or interpretation of the data|contributed to drafting of the manuscript|contributed to critical revision of the manuscript|contributed to statistical analysis	contributed to drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
5878413	29603900	RA	2	contributed to study concept and design|contributed to acquisition, analysis or interpretation of the data|contributed to drafting of the manuscript|contributed to critical revision of the manuscript|contributed to statistical analysis	contributed to critical revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5878413	29603900	RA	2	contributed to study concept and design|contributed to acquisition, analysis or interpretation of the data|contributed to drafting of the manuscript|contributed to critical revision of the manuscript|contributed to statistical analysis	contributed to statistical analysis	Analyzed the data	Formal analysis	YES
5878413	29603900	UD	2	contributed to study concept and design|contributed to acquisition, analysis or interpretation of the data|contributed to critical revision of the manuscript	contributed to study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5878413	29603900	UD	2	contributed to study concept and design|contributed to acquisition, analysis or interpretation of the data|contributed to critical revision of the manuscript	contributed to acquisition, analysis or interpretation of the data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5878413	29603900	UD	2	contributed to study concept and design|contributed to acquisition, analysis or interpretation of the data|contributed to critical revision of the manuscript	contributed to critical revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5878413	29603900	YvD	2	contributed to critical revision of the manuscript|obtained funding	contributed to critical revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5878413	29603900	YvD	2	contributed to critical revision of the manuscript|obtained funding	obtained funding	-	Funding acquisition	YES
5615213	29018462	GH	PLoS52	participated in figure preparation	participated in figure preparation	-	Visualization	YES
5615213	29018462	LK	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5615213	29018462	LL	PLoS52	participated in experiment design and manuscript revision	participated in experiment design and manuscript revision	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
5615213	29018462	MH	PLoS52	carried out the experiments and drafted the manuscript|supplemented the experiment data for revised manuscript|analyzed the data	carried out the experiments and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5615213	29018462	MH	PLoS52	carried out the experiments and drafted the manuscript|supplemented the experiment data for revised manuscript|analyzed the data	supplemented the experiment data for revised manuscript	Wrote the paper	Writing - Review & Editing	YES
5615213	29018462	MH	PLoS52	carried out the experiments and drafted the manuscript|supplemented the experiment data for revised manuscript|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5615213	29018462	WY	PLoS52	supplemented the experiment data for revised manuscript|participated in figure preparation	supplemented the experiment data for revised manuscript	Wrote the paper	Writing - Review & Editing	YES
5615213	29018462	WY	PLoS52	supplemented the experiment data for revised manuscript|participated in figure preparation	participated in figure preparation	-	Visualization	YES
5615213	29018462	XJ	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5615213	29018462	XW	PLoS52	participated in experiment design and manuscript revision	participated in experiment design and manuscript revision	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
5615213	29018462	YT	PLoS52	participated in figure preparation	participated in figure preparation	-	Visualization	YES
5615213	29018462	YW	PLoS52	conceived the study, participated in its design and revised the manuscript	conceived the study, participated in its design and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
1762408	17205110	CZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762408	17205110	CZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762408	17205110	CZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762408	17205110	CZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762408	17205110	ET	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762408	17205110	ET	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762408	17205110	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762408	17205110	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762408	17205110	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762408	17205110	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762408	17205110	TC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762408	17205110	TC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762408	17205110	TC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762408	17205110	TS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
3478187	22681935	CT	2	imaging, proofread the manuscript and made suggestions	imaging, proofread the manuscript and made suggestions	Analyzed the data	Visualization	YES
3478187	22681935	DAT	2	carried out the peptide synthesis	carried out the peptide synthesis	Performed the experiments	Investigation	YES
3478187	22681935	EGG	2	participated in the biodistribution studies	participated in the biodistribution studies	-	-	NO
3478187	22681935	LB	2	carried out the peptide synthesis	carried out the peptide synthesis	Performed the experiments	Investigation	YES
3478187	22681935	PB	2	contributed to the dose calculation	contributed to the dose calculation	Analyzed the data	Formal analysis	YES
3478187	22681935	RS	2	supervised the study and proofread the manuscript	supervised the study and proofread the manuscript	-	Supervision	YES
3478187	22681935	SD	2	participated in the whole study and drafted the manuscript	participated in the whole study and drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
3478187	22681935	VM	2	carried out the peptide synthesis	carried out the peptide synthesis	Performed the experiments	Investigation	YES
4409116	25910061	AMT	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409116	25910061	AMT	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409116	25910061	AMT	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409116	25910061	EWL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409116	25910061	EWL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409116	25910061	EWL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409116	25910061	GV	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Discussion of data analysis and results	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409116	25910061	GV	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Discussion of data analysis and results	Performed the experiments	Performed the experiments	Investigation	YES
4409116	25910061	GV	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Discussion of data analysis and results	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409116	25910061	GV	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Discussion of data analysis and results	Discussion of data analysis and results	Analyzed the data	Formal analysis	YES
4409116	25910061	KAS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4409116	25910061	KAS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409116	25910061	RH	PLoS5	Wrote the paper|Discussion of data analysis and results	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409116	25910061	RH	PLoS5	Wrote the paper|Discussion of data analysis and results	Discussion of data analysis and results	Analyzed the data	Formal analysis	YES
4409116	25910061	SAB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4409116	25910061	SAB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5426028	28494755	All authors	PLoS52	contributed and gave final approval of the manuscript for publication	contributed and gave final approval of the manuscript for publication	-	-	NO
5426028	28494755	DKH	PLoS52	designed research and experimental strategy	designed research and experimental strategy	Conceived and designed the experiments	Methodology	YES
5426028	28494755	KSL	PLoS52	designed research and experimental strategy	designed research and experimental strategy	Conceived and designed the experiments	Methodology	YES
5426028	28494755	NK	PLoS52	designed research and experimental strategy|conducted the experiments|analyzed the data|drafted manuscript	designed research and experimental strategy	Conceived and designed the experiments	Methodology	YES
5426028	28494755	NK	PLoS52	designed research and experimental strategy|conducted the experiments|analyzed the data|drafted manuscript	conducted the experiments	Performed the experiments	Investigation	YES
5426028	28494755	NK	PLoS52	designed research and experimental strategy|conducted the experiments|analyzed the data|drafted manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5426028	28494755	NK	PLoS52	designed research and experimental strategy|conducted the experiments|analyzed the data|drafted manuscript	drafted manuscript	Wrote the paper	Writing - Original Draft	YES
5426028	28494755	WC	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5426028	28494755	WMW	PLoS52	designed research and experimental strategy|drafted manuscript	designed research and experimental strategy	Conceived and designed the experiments	Methodology	YES
5426028	28494755	WMW	PLoS52	designed research and experimental strategy|drafted manuscript	drafted manuscript	Wrote the paper	Writing - Original Draft	YES
5426028	28494755	YZ	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5426028	28494755	ZF	PLoS52	designed research and experimental strategy	designed research and experimental strategy	Conceived and designed the experiments	Methodology	YES
5878414	29603888	ADP	2	contributed to the conception of the study design|conducted the analysis|analysed and interpreted the data|wrote the first manuscript draft|edited the manuscript	contributed to the conception of the study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5878414	29603888	ADP	2	contributed to the conception of the study design|conducted the analysis|analysed and interpreted the data|wrote the first manuscript draft|edited the manuscript	conducted the analysis	Performed the experiments	Investigation	YES
5878414	29603888	ADP	2	contributed to the conception of the study design|conducted the analysis|analysed and interpreted the data|wrote the first manuscript draft|edited the manuscript	analysed and interpreted the data	Analyzed the data	Formal analysis	YES
5878414	29603888	ADP	2	contributed to the conception of the study design|conducted the analysis|analysed and interpreted the data|wrote the first manuscript draft|edited the manuscript	wrote the first manuscript draft	Wrote the paper	Writing - Original Draft	YES
5878414	29603888	ADP	2	contributed to the conception of the study design|conducted the analysis|analysed and interpreted the data|wrote the first manuscript draft|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5878414	29603888	BG	2	contributed to the conception of the study design|acquired data|edited the manuscript	contributed to the conception of the study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5878414	29603888	BG	2	contributed to the conception of the study design|acquired data|edited the manuscript	acquired data	Performed the experiments	Investigation	YES
5878414	29603888	BG	2	contributed to the conception of the study design|acquired data|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5878414	29603888	BO	2	conducted the analysis|analysed and interpreted the data|wrote the first manuscript draft|edited the manuscript	conducted the analysis	Performed the experiments	Investigation	YES
5878414	29603888	BO	2	conducted the analysis|analysed and interpreted the data|wrote the first manuscript draft|edited the manuscript	analysed and interpreted the data	Analyzed the data	Formal analysis	YES
5878414	29603888	BO	2	conducted the analysis|analysed and interpreted the data|wrote the first manuscript draft|edited the manuscript	wrote the first manuscript draft	Wrote the paper	Writing - Original Draft	YES
5878414	29603888	BO	2	conducted the analysis|analysed and interpreted the data|wrote the first manuscript draft|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5878414	29603888	CJS	2	acquired data|edited the manuscript	acquired data	Performed the experiments	Investigation	YES
5878414	29603888	CJS	2	acquired data|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5878414	29603888	EL	2	analysed and interpreted the data|edited the manuscript	analysed and interpreted the data	Analyzed the data	Formal analysis	YES
5878414	29603888	EL	2	analysed and interpreted the data|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5878414	29603888	FM	2	acquired data|edited the manuscript	acquired data	Performed the experiments	Investigation	YES
5878414	29603888	FM	2	acquired data|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5878414	29603888	KAF	2	contributed to the conception of the study design|analysed and interpreted the data|edited the manuscript	contributed to the conception of the study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5878414	29603888	KAF	2	contributed to the conception of the study design|analysed and interpreted the data|edited the manuscript	analysed and interpreted the data	Analyzed the data	Formal analysis	YES
5878414	29603888	KAF	2	contributed to the conception of the study design|analysed and interpreted the data|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5878414	29603888	MES	2	conducted the analysis|analysed and interpreted the data|edited the manuscript	conducted the analysis	Performed the experiments	Investigation	YES
5878414	29603888	MES	2	conducted the analysis|analysed and interpreted the data|edited the manuscript	analysed and interpreted the data	Analyzed the data	Formal analysis	YES
5878414	29603888	MES	2	conducted the analysis|analysed and interpreted the data|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5878414	29603888	PML	2	contributed to the conception of the study design|conducted the analysis|acquired data|analysed and interpreted the data|wrote the first manuscript draft|edited the manuscript	contributed to the conception of the study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5878414	29603888	PML	2	contributed to the conception of the study design|conducted the analysis|acquired data|analysed and interpreted the data|wrote the first manuscript draft|edited the manuscript	conducted the analysis	Performed the experiments	Investigation	YES
5878414	29603888	PML	2	contributed to the conception of the study design|conducted the analysis|acquired data|analysed and interpreted the data|wrote the first manuscript draft|edited the manuscript	acquired data	Performed the experiments	Investigation	YES
5878414	29603888	PML	2	contributed to the conception of the study design|conducted the analysis|acquired data|analysed and interpreted the data|wrote the first manuscript draft|edited the manuscript	analysed and interpreted the data	Analyzed the data	Formal analysis	YES
5878414	29603888	PML	2	contributed to the conception of the study design|conducted the analysis|acquired data|analysed and interpreted the data|wrote the first manuscript draft|edited the manuscript	wrote the first manuscript draft	Wrote the paper	Writing - Original Draft	YES
5878414	29603888	PML	2	contributed to the conception of the study design|conducted the analysis|acquired data|analysed and interpreted the data|wrote the first manuscript draft|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5878414	29603888	RAP	2	conducted the analysis|analysed and interpreted the data|edited the manuscript	conducted the analysis	Performed the experiments	Investigation	YES
5878414	29603888	RAP	2	conducted the analysis|analysed and interpreted the data|edited the manuscript	analysed and interpreted the data	Analyzed the data	Formal analysis	YES
5878414	29603888	RAP	2	conducted the analysis|analysed and interpreted the data|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5878414	29603888	RLM	2	conducted the analysis|analysed and interpreted the data|edited the manuscript	conducted the analysis	Performed the experiments	Investigation	YES
5878414	29603888	RLM	2	conducted the analysis|analysed and interpreted the data|edited the manuscript	analysed and interpreted the data	Analyzed the data	Formal analysis	YES
5878414	29603888	RLM	2	conducted the analysis|analysed and interpreted the data|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5878414	29603888	RPW	2	contributed to the conception of the study design|analysed and interpreted the data|edited the manuscript	contributed to the conception of the study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5878414	29603888	RPW	2	contributed to the conception of the study design|analysed and interpreted the data|edited the manuscript	analysed and interpreted the data	Analyzed the data	Formal analysis	YES
5878414	29603888	RPW	2	contributed to the conception of the study design|analysed and interpreted the data|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5878414	29603888	VGV	2	contributed to the conception of the study design|acquired data|edited the manuscript	contributed to the conception of the study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5878414	29603888	VGV	2	contributed to the conception of the study design|acquired data|edited the manuscript	acquired data	Performed the experiments	Investigation	YES
5878414	29603888	VGV	2	contributed to the conception of the study design|acquired data|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
4538332	26339591	All authors	2	read, edited, and approved the final paper	read, edited, and approved the final paper	Wrote the paper	Writing - Review & Editing	YES
4538332	26339591	Chao-Chin Wu	2	contributed to the algorithm|analyzed the results and wrote the report|supervised the work	contributed to the algorithm	Contributed reagents/materials/analysis tools	Software	YES
4538332	26339591	Chao-Chin Wu	2	contributed to the algorithm|analyzed the results and wrote the report|supervised the work	analyzed the results and wrote the report	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4538332	26339591	Chao-Chin Wu	2	contributed to the algorithm|analyzed the results and wrote the report|supervised the work	supervised the work	-	Supervision	YES
4538332	26339591	Liang-Tsung Huang	2	contributed to the algorithm|analyzed the results and wrote the report	contributed to the algorithm	Contributed reagents/materials/analysis tools	Software	YES
4538332	26339591	Liang-Tsung Huang	2	contributed to the algorithm|analyzed the results and wrote the report	analyzed the results and wrote the report	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4538332	26339591	Lien-Fu Lai	2	contributed to the algorithm	contributed to the algorithm	Contributed reagents/materials/analysis tools	Software	YES
4538332	26339591	Yun-Ju Li	2	implemented the algorithm and carried out experiments	implemented the algorithm and carried out experiments	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5615247	29018464	HC	2	designed the study, performed the experiment, collected and analyzed the data, and wrote the manuscript	designed the study, performed the experiment, collected and analyzed the data, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5615247	29018464	JY	2	discussed the experiment design and manuscript writing	discussed the experiment design and manuscript writing	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5615247	29018464	KW	2	discussed the experiment design and manuscript writing	discussed the experiment design and manuscript writing	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5615247	29018464	YD	2	discussed the experiment design and manuscript writing	discussed the experiment design and manuscript writing	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5615247	29018464	YN	2	designed the study, performed the experiment, collected and analyzed the data, and wrote the manuscript	designed the study, performed the experiment, collected and analyzed the data, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
3483228	23067778	AL	2	was involved in interpreting data and drafting and improving the manuscript	was involved in interpreting data and drafting and improving the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
3483228	23067778	BvB	2	was the clinical supervisor involved in screening of participants and assisting in the pet data acquisition and helped draft the manuscript	was the clinical supervisor involved in screening of participants and assisting in the pet data acquisition and helped draft the manuscript	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Original Draft	YES
3483228	23067778	DvA	2	acquired the pet data, performed data analysis and wrote the manuscript	acquired the pet data, performed data analysis and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3483228	23067778	JE	2	was involved in tracer synthesis and quality control of tracer synthesis processes	was involved in tracer synthesis and quality control of tracer synthesis processes	Performed the experiments	Validation	YES
3483228	23067778	JvS	2	advised about the use of genetic terminology	advised about the use of genetic terminology	Performed the experiments	Investigation	YES
3483228	23067778	MK	2	was involved in the first ideas for the studies and study design	was involved in the first ideas for the studies and study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
3483228	23067778	ML	2	supervised the pet data analysis	supervised the pet data analysis	Analyzed the data	Formal analysis|Supervision	YES
3483228	23067778	PR	2	performed the dna isolation and molecular analysis	performed the dna isolation and molecular analysis	Performed the experiments	Investigation	YES
3483228	23067778	PS	2	assisted in recruiting the ad patients	assisted in recruiting the ad patients	Performed the experiments	Investigation	YES
3483228	23067778	RS	2	was involved in quality control of the pet tracer and metabolite analysis and performed quality control of the metabolite data	was involved in quality control of the pet tracer and metabolite analysis and performed quality control of the metabolite data	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Validation	YES
4409117	25910266	ASS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409117	25910266	BDS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409117	25910266	BDS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409117	25910266	CMO	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409117	25910266	CMO	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409117	25910266	CMO	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409117	25910266	MDB	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409117	25910266	MDB	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409117	25910266	NPM	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4409117	25910266	NPM	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409117	25910266	YWL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409117	25910266	YWL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409117	25910266	YWL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5426056	28494783	EG	2	was involved in project planning, provided experimental data and contributed to writing the paper	was involved in project planning, provided experimental data and contributed to writing the paper	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Methodology|Resources|Writing - Original Draft	YES
5426056	28494783	EGE	2	was involved in project planning, organized the fatty acid measurements and contributed to writing the paper	was involved in project planning, organized the fatty acid measurements and contributed to writing the paper	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Project administration|Writing - Original Draft	YES
5426056	28494783	HG	2	conducted imputation work and took part in writing the paper	conducted imputation work and took part in writing the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5426056	28494783	MPK	2	was involved in project planning, organized data for sequencing and contributed to writing the paper	was involved in project planning, organized data for sequencing and contributed to writing the paper	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Project administration|Writing - Original Draft	YES
5426056	28494783	MvS	2	conducted gwas analyses, snp detection and drafted the paper	conducted gwas analyses, snp detection and drafted the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5426056	28494783	RRF	2	contributed to fatty acid measurements and took part in writing the paper	contributed to fatty acid measurements and took part in writing the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5426056	28494783	SL	2	was involved in project planning and contributed to writing the paper	was involved in project planning and contributed to writing the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
1762409	17205129	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762409	17205129	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762409	17205129	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762409	17205129	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762409	17205129	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762409	17205129	NG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762409	17205129	NG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762409	17205129	NG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762409	17205129	NG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762409	17205129	NG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5878415	29603882	ADP	2	contributed to the analysis and interpretation of data for the work	contributed to the analysis and interpretation of data for the work	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5878415	29603882	AZ	2	contributed to the conception and design of the work|contributed to the analysis and interpretation of data for the work	contributed to the conception and design of the work	Conceived and designed the experiments	Conceptualization	YES
5878415	29603882	AZ	2	contributed to the conception and design of the work|contributed to the analysis and interpretation of data for the work	contributed to the analysis and interpretation of data for the work	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5878415	29603882	All authors	2	contributed substantially to drafting and revising the work critically for intellectual content and have approved the final version of the work to be published	contributed substantially to drafting and revising the work critically for intellectual content and have approved the final version of the work to be published	Wrote the paper	Writing - Original Draft	YES
5878415	29603882	BBR	2	contributed to the acquisition of data	contributed to the acquisition of data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5878415	29603882	KAF	2	contributed to the conception and design of the work|contributed to the analysis and interpretation of data for the work	contributed to the conception and design of the work	Conceived and designed the experiments	Conceptualization	YES
5878415	29603882	KAF	2	contributed to the conception and design of the work|contributed to the analysis and interpretation of data for the work	contributed to the analysis and interpretation of data for the work	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5878415	29603882	KHM	2	contributed to the acquisition of data	contributed to the acquisition of data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5878415	29603882	MH	2	contributed to the analysis and interpretation of data for the work	contributed to the analysis and interpretation of data for the work	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5878415	29603882	NK	2	contributed to the acquisition of data	contributed to the acquisition of data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5878415	29603882	RPW	2	contributed to the analysis and interpretation of data for the work	contributed to the analysis and interpretation of data for the work	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
3489558	22697397	H. All	2	authors contributed to the scientific and intellectual discussion and interpretation of the data	authors contributed to the scientific and intellectual discussion and interpretation of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
3489558	22697397	NR	2	carried out the animal trial|drafted the manuscript	carried out the animal trial	Performed the experiments	Investigation	YES
3489558	22697397	NR	2	carried out the animal trial|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
3489558	22697397	RNA	2	preprocessing of the data	preprocessing of the data	Analyzed the data	Data curation	YES
3489558	22697397	TZP	2	carried out the animal trial	carried out the animal trial	Performed the experiments	Investigation	YES
3489558	22697397	all authors	2	participated with substantial input and revision of the manuscript	participated with substantial input and revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
3412198	22870166	E Maheu	3	Critical revision of the article for important intellectual content|Final approval of article	Critical revision of the article for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
3412198	22870166	E Maheu	3	Critical revision of the article for important intellectual content|Final approval of article	Final approval of article	-	-	NO
3412198	22870166	H Schneider	3	Conception and design|Analysis and interpretation of the data|Drafting of the article|Critical revision of the article for important intellectual content|Final approval of article	Conception and design	Conceived and designed the experiments	Conceptualization	YES
3412198	22870166	H Schneider	3	Conception and design|Analysis and interpretation of the data|Drafting of the article|Critical revision of the article for important intellectual content|Final approval of article	Analysis and interpretation of the data	Analyzed the data	Formal analysis	YES
3412198	22870166	H Schneider	3	Conception and design|Analysis and interpretation of the data|Drafting of the article|Critical revision of the article for important intellectual content|Final approval of article	Drafting of the article	Wrote the paper	Writing - Original Draft	YES
3412198	22870166	H Schneider	3	Conception and design|Analysis and interpretation of the data|Drafting of the article|Critical revision of the article for important intellectual content|Final approval of article	Critical revision of the article for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
3412198	22870166	H Schneider	3	Conception and design|Analysis and interpretation of the data|Drafting of the article|Critical revision of the article for important intellectual content|Final approval of article	Final approval of article	-	-	NO
3412198	22870166	M Cucherat	3	Conception and design|Analysis and interpretation of the data|Critical revision of the article for important intellectual content|Final approval of article	Conception and design	Conceived and designed the experiments	Conceptualization	YES
3412198	22870166	M Cucherat	3	Conception and design|Analysis and interpretation of the data|Critical revision of the article for important intellectual content|Final approval of article	Analysis and interpretation of the data	Analyzed the data	Formal analysis	YES
3412198	22870166	M Cucherat	3	Conception and design|Analysis and interpretation of the data|Critical revision of the article for important intellectual content|Final approval of article	Critical revision of the article for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
3412198	22870166	M Cucherat	3	Conception and design|Analysis and interpretation of the data|Critical revision of the article for important intellectual content|Final approval of article	Final approval of article	-	-	NO
4409118	25910247	JS	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409118	25910247	KK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409118	25910247	KT	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409118	25910247	MK	PLoS5	Performed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409118	25910247	MK	PLoS5	Performed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409118	25910247	MN	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409118	25910247	MO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409118	25910247	MO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409118	25910247	MO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409118	25910247	MO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409118	25910247	SU	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409118	25910247	TK	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409118	25910247	TT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409118	25910247	TT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409118	25910247	TT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409118	25910247	TT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409118	25910247	YT	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409118	25910247	YU	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5615380	29018455	AM	2	contributed to the analysis, data interpretation, and writing	contributed to the analysis, data interpretation, and writing	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources	YES
5615380	29018455	JS	2	conducted the field portion of the experiment and contributed to the planning, data interpretation, and writing	conducted the field portion of the experiment and contributed to the planning, data interpretation, and writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources	YES
5615380	29018455	NB	2	contributed to the planning, analysis, interpretation, and writing	contributed to the planning, analysis, interpretation, and writing	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology	YES
3502253	22531468	BBB	2	selected the patient studies and performed the lesion delineation in the original patient data	selected the patient studies and performed the lesion delineation in the original patient data	Performed the experiments	Investigation	YES
3502253	22531468	FH	2	developed and implemented the pvc algorithm, performed part of the data analysis and is the main author of the manuscript	developed and implemented the pvc algorithm, performed part of the data analysis and is the main author of the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Software|Writing - Original Draft	YES
3502253	22531468	JK	2	provided intellectual input and reviewed the manuscript	provided intellectual input and reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
3502253	22531468	JL	2	performed part of the data analysis	performed part of the data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3502253	22531468	JP	2	performed part of the data analysis	performed part of the data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3502253	22531468	JS	2	provided intellectual input and reviewed the manuscript	provided intellectual input and reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
3502253	22531468	LO	2	selected the patient studies and performed the lesion delineation in the original patient data	selected the patient studies and performed the lesion delineation in the original patient data	Performed the experiments	Investigation	YES
3502253	22531468	PVC	2	wrote part of the manuscript	wrote part of the manuscript	Wrote the paper	Writing - Original Draft	YES
3502476	23034289	AAL	2	reviewed the manuscript, contributed to the intellectual content and approved the final content of the manuscript	reviewed the manuscript, contributed to the intellectual content and approved the final content of the manuscript	Wrote the paper	Writing - Review & Editing	YES
3502476	23034289	All authors	2	reviewed the collected data and interpretation, provided feedback for further research during the study and approved the final submitted version of this manuscript	reviewed the collected data and interpretation, provided feedback for further research during the study and approved the final submitted version of this manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
3502476	23034289	AvB	2	collected the data and reviewed the manuscript	collected the data and reviewed the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
3502476	23034289	CT	2	delineation and reviewed the manuscript	delineation and reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
3502476	23034289	DdR	2	provided pet image data and critically reviewed the manuscript	provided pet image data and critically reviewed the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Visualization|Writing - Review & Editing	YES
3502476	23034289	FHPvV	2	performed data interpretation, implemented some of the tumor delineation methods, assisted in drafting the manuscript and supervised the project	performed data interpretation, implemented some of the tumor delineation methods, assisted in drafting the manuscript and supervised the project	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Supervision|Writing - Original Draft	YES
3502476	23034289	MY	2	implemented some of the tools to perform tumor delineations and critically reviewed manuscript	implemented some of the tools to perform tumor delineations and critically reviewed manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
3502476	23034289	OSH	2	reviewed the manuscript and approved its final content	reviewed the manuscript and approved its final content	Wrote the paper	Writing - Review & Editing	YES
3502476	23034289	PC	2	performed data analysis and data interpretation, and is the main author of the manuscript	performed data analysis and data interpretation, and is the main author of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3502476	23034289	RB	2	performed a study design, implemented some of the tumor delineation methods, contributed to the intellectual content and reviewed and approved the final content of the manuscript	performed a study design, implemented some of the tumor delineation methods, contributed to the intellectual content and reviewed and approved the final content of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
3502476	23034289	WvE	2	provided the data and reviewed the manuscript	provided the data and reviewed the manuscript	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Review & Editing	YES
1762410	17205112	AK	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762410	17205112	CV	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762410	17205112	DS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762410	17205112	GK	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762410	17205112	JZ	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762410	17205112	JZ	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762410	17205112	NO	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762410	17205112	NO	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762410	17205112	VA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762410	17205112	VA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762410	17205112	VA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762410	17205112	VA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762410	17205112	VH	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762410	17205112	VH	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5878416	29603879	DC	PLoS52	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5878416	29603879	LM	PLoS52	performed the research|drafted the manuscript	performed the research	Performed the experiments	Investigation	YES
5878416	29603879	LM	PLoS52	performed the research|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5878416	29603879	VS	PLoS52	designed the research|drafted the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
5878416	29603879	VS	PLoS52	designed the research|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5878416	29603879	all authors	PLoS52	analysed the data|critically revised the manuscript for important intellectual content	analysed the data	Analyzed the data	Formal analysis	YES
5878416	29603879	all authors	PLoS52	analysed the data|critically revised the manuscript for important intellectual content	critically revised the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5615928	29018463	AB	2	did the gc-ms-analysis	did the gc-ms-analysis	-	-	NO
5615928	29018463	AS	2	performed the phytohormone quantification and gave advice on the statistical analysis	performed the phytohormone quantification and gave advice on the statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5615928	29018463	BR	2	the manuscript	the manuscript	-	-	NO
5615928	29018463	CH	2	genotyped cpr1-4 and cpr1-5 , did the qrt-pcrs depicted in figures 2 , 5 6 11|performed also the ros staining experiments and drafted parts of the manuscript and figures	genotyped cpr1-4 and cpr1-5 , did the qrt-pcrs depicted in figures 2 , 5 6 11	Performed the experiments	Investigation|Visualization	YES
5615928	29018463	CH	2	genotyped cpr1-4 and cpr1-5 , did the qrt-pcrs depicted in figures 2 , 5 6 11|performed also the ros staining experiments and drafted parts of the manuscript and figures	performed also the ros staining experiments and drafted parts of the manuscript and figures	Performed the experiments|Wrote the paper	Investigation|Visualization|Writing - Original Draft	YES
5615928	29018463	Carl-Severing-Berufskolleg	2	did the calculations and prepared the figures	did the calculations and prepared the figures	Analyzed the data	Formal analysis|Visualization	YES
5615928	29018463	ER	2	genotyped cpr1-4 and cpr1-5 , did the qrt-pcrs depicted in figures 2 , 5 6 11|also did the habitus documentation, crossed the mutants and selected the lines for further analysis, performed the caps marker analysis and the qrt-pcrs depicted in figures 3 10	genotyped cpr1-4 and cpr1-5 , did the qrt-pcrs depicted in figures 2 , 5 6 11	Performed the experiments	Investigation|Visualization	YES
5615928	29018463	ER	2	genotyped cpr1-4 and cpr1-5 , did the qrt-pcrs depicted in figures 2 , 5 6 11|also did the habitus documentation, crossed the mutants and selected the lines for further analysis, performed the caps marker analysis and the qrt-pcrs depicted in figures 3 10	also did the habitus documentation, crossed the mutants and selected the lines for further analysis, performed the caps marker analysis and the qrt-pcrs depicted in figures 3 10	Performed the experiments	Investigation|Visualization	YES
5615928	29018463	IH	2	performed the ascorbate measurements, the qrt-pcrs depicted in figures 7 8 , prepared the samples for the gc-ms analysis and drafted the figures	performed the ascorbate measurements, the qrt-pcrs depicted in figures 7 8 , prepared the samples for the gc-ms analysis and drafted the figures	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Visualization|Writing - Original Draft	YES
5615928	29018463	JvB	2	quantified the ros levels	quantified the ros levels	-	-	NO
5615928	29018463	KN	2	did the gc-ms-analysis	did the gc-ms-analysis	-	-	NO
5615928	29018463	TL	2	performed the phytohormone quantification and gave advice on the statistical analysis	performed the phytohormone quantification and gave advice on the statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3502552	22673157	FZ	2	was involved in the chemical characterization of the molecules and analysis	was involved in the chemical characterization of the molecules and analysis	Performed the experiments	Investigation	YES
3502552	22673157	KL	2	carried out the in vivo experiments and analysis	carried out the in vivo experiments and analysis	Performed the experiments	Investigation	YES
3502552	22673157	MS	2	participated in the conception and design of the study and carried out the peptide/chemical synthesis	participated in the conception and design of the study and carried out the peptide/chemical synthesis	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
3502552	22673157	MaE	2	contributed in the conception and design of the study, in the analysis and interpretation of data, and in the final approval of the manuscript	contributed in the conception and design of the study, in the analysis and interpretation of data, and in the final approval of the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Methodology|Resources	YES
3502552	22673157	MiE	2	contributed in revising the manuscript critically	contributed in revising the manuscript critically	Wrote the paper	Writing - Review & Editing	YES
3502552	22673157	UBW	2	carried out the in vitro experiments and contributed in the analysis and interpretation of data	carried out the in vitro experiments and contributed in the analysis and interpretation of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
3502552	22673157	UH	2	contributed in revising the manuscript critically	contributed in revising the manuscript critically	Wrote the paper	Writing - Review & Editing	YES
3502552	22673157	WM	2	contributed in revising the manuscript critically	contributed in revising the manuscript critically	Wrote the paper	Writing - Review & Editing	YES
4409119	25910043	BJH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409119	25910043	BJH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409119	25910043	BJH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409119	25910043	BJH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409119	25910043	DC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409119	25910043	DC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409119	25910043	DC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409119	25910043	LS	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409119	25910043	SEH	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409119	25910043	SEH	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409119	25910043	SEH	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762411	17205115	AP	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762411	17205115	AP	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762411	17205115	DB	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762411	17205115	DB	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1762411	17205115	DT	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762411	17205115	LM	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762411	17205115	LM	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1762411	17205115	PS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1762411	17205115	PS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5894250	29638044	G. All	2	authors read, commented on and approved the final manuscript	authors read, commented on and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5894250	29638044	RTG	2	wrote the modelling code and setup the online code repository	wrote the modelling code and setup the online code repository	Performed the experiments|Wrote the paper	Methodology|Software|Writing - Original Draft	YES
3504567	22999160	AT	2	participated in the data analysis and manuscript editing	participated in the data analysis and manuscript editing	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
3504567	22999160	AY	2	participated in the data analysis	participated in the data analysis	Analyzed the data	Formal analysis	YES
3504567	22999160	BCG	2	participated in the study design, performed the experiments and data analysis, and edited the manuscript	participated in the study design, performed the experiments and data analysis, and edited the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Review & Editing	YES
3504567	22999160	KC	2	participated in the experiments and data analysis	participated in the experiments and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3504567	22999160	MAK	2	participated in study design and manuscript editing	participated in study design and manuscript editing	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
3504567	22999160	MP	2	participated in the study design and coordination and reviewed the data analysis	participated in the study design and coordination and reviewed the data analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology|Project administration	YES
3504567	22999160	SJM	2	conceived of the study, participated in the design and coordination, reviewed the data analysis, and edited and approved the final manuscript	conceived of the study, participated in the design and coordination, reviewed the data analysis, and edited and approved the final manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Project administration|Writing - Review & Editing	YES
5622183	28993789	All authors	2	approved the manuscript and the version to be published	approved the manuscript and the version to be published	-	-	NO
5622183	28993789	HS	2	wrote and revised the manuscript	wrote and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5622183	28993789	JL	2	provided suggestions and revised the manuscript	provided suggestions and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5622183	28993789	WH	2	provided suggestions and revised the manuscript	provided suggestions and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5427609	28499406	DAY	PLoS52	wrote and corrected the manuscript	wrote and corrected the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5427609	28499406	DL	PLoS52	analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
5427609	28499406	HK	PLoS52	supervised and managed the whole study	supervised and managed the whole study	-	Project administration|Supervision	YES
5427609	28499406	JK	PLoS52	analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
5427609	28499406	JWH	PLoS52	designed and implemented the method and wrote the methods in the manuscript	designed and implemented the method and wrote the methods in the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5427609	28499406	KK	PLoS52	analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
5427609	28499406	OSJ	PLoS52	supervised and managed the whole study	supervised and managed the whole study	-	Project administration|Supervision	YES
5427609	28499406	SC	PLoS52	wrote and corrected the manuscript	wrote and corrected the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5427609	28499406	SJK	PLoS52	designed the experiment and method, performed the analysis of genome data, and drafted the manuscript	designed the experiment and method, performed the analysis of genome data, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5897849	29479867	AH	2	wrote the first draft of the study protocol	wrote the first draft of the study protocol	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5897849	29479867	AP	2	assisted in implementation, fieldwork, and data collection at study sites and regional data centres	assisted in implementation, fieldwork, and data collection at study sites and regional data centres	Performed the experiments	Investigation	YES
5897849	29479867	AT	2	assisted in implementation, fieldwork, and data collection at study sites and regional data centres	assisted in implementation, fieldwork, and data collection at study sites and regional data centres	Performed the experiments	Investigation	YES
5897849	29479867	All authors	2	reviewed and approved the final version for submission	reviewed and approved the final version for submission	-	-	NO
5897849	29479867	DN	2	assisted in implementation, fieldwork, and data collection at study sites and regional data centres	assisted in implementation, fieldwork, and data collection at study sites and regional data centres	Performed the experiments	Investigation	YES
5897849	29479867	EZ	2	wrote the first draft of the study protocol	wrote the first draft of the study protocol	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5897849	29479867	FD	2	assisted in implementation, fieldwork, and data collection at study sites and regional data centres	assisted in implementation, fieldwork, and data collection at study sites and regional data centres	Performed the experiments	Investigation	YES
5897849	29479867	IeDEA	2	data centres	data centres	-	-	NO
5897849	29479867	JS	2	assisted in implementation, fieldwork, and data collection at study sites and regional data centres	assisted in implementation, fieldwork, and data collection at study sites and regional data centres	Performed the experiments	Investigation	YES
5897849	29479867	ME	2	wrote the first draft of the study protocol|obtained funding for the project	wrote the first draft of the study protocol	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5897849	29479867	ME	2	wrote the first draft of the study protocol|obtained funding for the project	obtained funding for the project	-	Funding acquisition	YES
5897849	29479867	TN	2	assisted in implementation, fieldwork, and data collection at study sites and regional data centres	assisted in implementation, fieldwork, and data collection at study sites and regional data centres	Performed the experiments	Investigation	YES
5897849	29479867	all authors	2	contributed to the final version of the protocol|commented on earlier drafts of the report	contributed to the final version of the protocol	Conceived and designed the experiments	Methodology	YES
5897849	29479867	all authors	2	contributed to the final version of the protocol|commented on earlier drafts of the report	commented on earlier drafts of the report	Wrote the paper	Writing - Original Draft	YES
4409146	25910275	BH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409146	25910275	BH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409146	25910275	BH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409146	25910275	GS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409146	25910275	GS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409146	25910275	GS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409146	25910275	KD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409146	25910275	KD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409146	25910275	KD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409146	25910275	KD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409146	25910275	SB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409146	25910275	ST	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409146	25910275	ST	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4409146	25910275	ST	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762412	17205137	AB	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762412	17205137	JP	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762412	17205137	TC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762412	17205137	TC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762412	17205137	TC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762412	17205137	TC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762412	17205137	TC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762412	17205137	WW	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
3506555	22747744	ADW	2	were in charge of the study, synthesis, radiosynthesis as well as acquiring, analyzing and interpreting the data	were in charge of the study, synthesis, radiosynthesis as well as acquiring, analyzing and interpreting the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3506555	22747744	Each author	2	contributed significantly to the submitted work, and all authors assisted in drafting the manuscript	contributed significantly to the submitted work, and all authors assisted in drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
3506555	22747744	JE	2	were in charge of the study, synthesis, radiosynthesis as well as acquiring, analyzing and interpreting the data	were in charge of the study, synthesis, radiosynthesis as well as acquiring, analyzing and interpreting the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3506555	22747744	JV	2	were in charge of the study, synthesis, radiosynthesis as well as acquiring, analyzing and interpreting the data	were in charge of the study, synthesis, radiosynthesis as well as acquiring, analyzing and interpreting the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3506555	22747744	ML	2	were in charge of the animal study and analysis of the animal pet data	were in charge of the animal study and analysis of the animal pet data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3506555	22747744	MPJM	2	assisted with the radiosynthesis	assisted with the radiosynthesis	-	-	NO
3506555	22747744	MR	2	was in charge of the metabolite analysis	was in charge of the metabolite analysis	-	-	NO
3506555	22747744	PET	2	contributed to the design of the study, analysis and interpretation of data	contributed to the design of the study, analysis and interpretation of data	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Methodology|Resources	YES
3506555	22747744	SS	2	were in charge of the animal study and analysis of the animal pet data	were in charge of the animal study and analysis of the animal pet data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5622202	28993785	AB	2	contributed to study conception and design, conduct of the statistical modeling analyses, interpretation of the results, and writing of the manuscript	contributed to study conception and design, conduct of the statistical modeling analyses, interpretation of the results, and writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5622202	28993785	AH	2	contributed to study conception and design, molecular analysis, interpretation of the results, and writing of the manuscript	contributed to study conception and design, molecular analysis, interpretation of the results, and writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5622202	28993785	DC	2	conceived the study and its design, conducted the statistical and spatial modeling analyses, and wrote the first draft of the paper	conceived the study and its design, conducted the statistical and spatial modeling analyses, and wrote the first draft of the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
5622202	28993785	DR	2	conceived the study and its design, conducted the statistical and spatial modeling analyses, and wrote the first draft of the paper	conceived the study and its design, conducted the statistical and spatial modeling analyses, and wrote the first draft of the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
5622202	28993785	DT	2	contributed to study conception and design, molecular analysis, interpretation of the results, and writing of the manuscript	contributed to study conception and design, molecular analysis, interpretation of the results, and writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5622202	28993785	MT	2	contributed to study conception and design, conduct of the statistical modeling analyses, interpretation of the results, and writing of the manuscript	contributed to study conception and design, conduct of the statistical modeling analyses, interpretation of the results, and writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
1762413	17205131	KG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1762413	17205131	KG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762413	17205131	ME	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762413	17205131	ME	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762413	17205131	MS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762413	17205131	MS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762413	17205131	MS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762413	17205131	NG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1762413	17205131	NG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762413	17205131	TB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1762413	17205131	TB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409147	25909849	AS	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409147	25909849	LMW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409147	25909849	LMW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409147	25909849	LMW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409147	25909849	LMW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409147	25909849	MT	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409147	25909849	RTA	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409147	25909849	US	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409147	25909849	US	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409147	25909849	US	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3506556	22564761	AD	2	carried out the manual co-registration method and contributed to the draft of the manuscript	carried out the manual co-registration method and contributed to the draft of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3506556	22564761	AG	2	carried out the animal experiments and the fdot reconstructions, and contributed to the draft of the manuscript and the design of the study	carried out the animal experiments and the fdot reconstructions, and contributed to the draft of the manuscript and the design of the study	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
3506556	22564761	BT	2	conceived of the project and participated in its design, coordination and in writing the manuscript	conceived of the project and participated in its design, coordination and in writing the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
3506556	22564761	FD	2	contributed to the mouse experiments and provided comments on the manuscript	contributed to the mouse experiments and provided comments on the manuscript	Performed the experiments	Investigation	YES
3506556	22564761	RB	2	participated in the design of the study and carried out the pet acquisitions	participated in the design of the study and carried out the pet acquisitions	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3506556	22564761	RT	2	participated in the design of the study	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
5429521	28499415	FM	2	prepared plant material for dna extraction	prepared plant material for dna extraction	Performed the experiments	Investigation	YES
5429521	28499415	HH	2	revised it|conducted bioinformatics	revised it	Wrote the paper	Writing - Review & Editing	YES
5429521	28499415	HH	2	revised it|conducted bioinformatics	conducted bioinformatics	Performed the experiments	Formal analysis|Investigation	YES
5429521	28499415	KS	2	revised it|constructed the linkage map	revised it	Wrote the paper	Writing - Review & Editing	YES
5429521	28499415	KS	2	revised it|constructed the linkage map	constructed the linkage map	Performed the experiments	Investigation	YES
5429521	28499415	MI	2	prepared plant material for dna extraction|initiated and coordinated the project	prepared plant material for dna extraction	Performed the experiments	Investigation	YES
5429521	28499415	MI	2	prepared plant material for dna extraction|initiated and coordinated the project	initiated and coordinated the project	Conceived and designed the experiments	Conceptualization|Project administration	YES
5429521	28499415	SI	2	constructed the linkage map|initiated and coordinated the project	constructed the linkage map	Performed the experiments	Investigation	YES
5429521	28499415	SI	2	constructed the linkage map|initiated and coordinated the project	initiated and coordinated the project	Conceived and designed the experiments	Conceptualization|Project administration	YES
5429521	28499415	SN	2	constructed the linkage map|conducted bioinformatics	constructed the linkage map	Performed the experiments	Investigation	YES
5429521	28499415	SN	2	constructed the linkage map|conducted bioinformatics	conducted bioinformatics	Performed the experiments	Formal analysis|Investigation	YES
5622203	28993786	CP	2	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5622203	28993786	HlW	2	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5622203	28993786	HtW	2	revised the language	revised the language	Wrote the paper	Writing - Review & Editing	YES
5622203	28993786	JS	2	revised the language	revised the language	Wrote the paper	Writing - Review & Editing	YES
5622203	28993786	LD	2	collected the sequences	collected the sequences	Performed the experiments	Investigation	YES
5622203	28993786	LG	2	collected the sequences	collected the sequences	Performed the experiments	Investigation	YES
5622203	28993786	QM	2	revised the language	revised the language	Wrote the paper	Writing - Review & Editing	YES
5622203	28993786	SF	2	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5622203	28993786	SY	2	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5622203	28993786	XJ	2	revised the language	revised the language	Wrote the paper	Writing - Review & Editing	YES
5622203	28993786	YG	2	performed the experiments and wrote the manuscript	performed the experiments and wrote the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4538339	26339600	Courtney E. Cross	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
4538339	26339600	Mai F. Tolba	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
5898225	29652100	DPW	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5898225	29652100	LG	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5898225	29652100	RMS	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
1762414	17205134	NV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762414	17205134	NV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762414	17205134	NV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762414	17205134	NV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762414	17205134	PE	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762414	17205134	PE	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762414	17205134	PE	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3506557	23021154	FS	2	carried out the manuscript drafting, data collection, and data analysis	carried out the manuscript drafting, data collection, and data analysis	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3506557	23021154	KS	2	conceived of the study and participated in its design and coordination	conceived of the study and participated in its design and coordination	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
3506557	23021154	MS	2	carried out the data collection, therapy evaluation, and data analysis	carried out the data collection, therapy evaluation, and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3506557	23021154	MWH	2	carried out the manuscript drafting, data collection, and statistical analysis	carried out the manuscript drafting, data collection, and statistical analysis	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3506557	23021154	PVH	2	conceived of the study, participated in its design and coordination, carried out the final manuscript drafting, and is the senior responsible study person	conceived of the study, participated in its design and coordination, carried out the final manuscript drafting, and is the senior responsible study person	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Project administration|Writing - Original Draft|Writing - Review & Editing	YES
3506557	23021154	UH	2	carried out the data collection, therapy evaluation, and data analysis	carried out the data collection, therapy evaluation, and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3506557	23021154	UvW	2	carried out the data collection, therapy evaluation, and data analysis	carried out the data collection, therapy evaluation, and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5622297	28993787	MB	2	designed, conducted, analyzed data and drafted the manuscript	designed, conducted, analyzed data and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5622297	28993787	MK	2	designed the experiment, advised with data interpretation and reviewed the manuscript	designed the experiment, advised with data interpretation and reviewed the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
5622297	28993787	PK	2	designed the experiment, advised with data interpretation and reviewed the manuscript	designed the experiment, advised with data interpretation and reviewed the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
5622297	28993787	SM	2	designed the experiment, advised with data interpretation and reviewed the manuscript	designed the experiment, advised with data interpretation and reviewed the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
5898226	29652098	AN	PLoS52	acquired the data	acquired the data	Performed the experiments	Investigation	YES
5898226	29652098	All authors	PLoS52	reviewed the manuscript and approved it for submission	reviewed the manuscript and approved it for submission	Wrote the paper	Writing - Review & Editing	YES
5898226	29652098	CHS	PLoS52	acquired the data	acquired the data	Performed the experiments	Investigation	YES
5898226	29652098	DN	PLoS52	conceived the study|designed the study|analysed the data|wrote the first draft	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5898226	29652098	DN	PLoS52	conceived the study|designed the study|analysed the data|wrote the first draft	designed the study	Conceived and designed the experiments	Methodology	YES
5898226	29652098	DN	PLoS52	conceived the study|designed the study|analysed the data|wrote the first draft	analysed the data	Analyzed the data	Formal analysis	YES
5898226	29652098	DN	PLoS52	conceived the study|designed the study|analysed the data|wrote the first draft	wrote the first draft	Wrote the paper	Writing - Original Draft	YES
5898226	29652098	EK	PLoS52	acquired the data	acquired the data	Performed the experiments	Investigation	YES
5898226	29652098	ELV	PLoS52	designed the study|acquired the data|analysed the data	designed the study	Conceived and designed the experiments	Methodology	YES
5898226	29652098	ELV	PLoS52	designed the study|acquired the data|analysed the data	acquired the data	Performed the experiments	Investigation	YES
5898226	29652098	ELV	PLoS52	designed the study|acquired the data|analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
5898226	29652098	LFS	PLoS52	designed the study|acquired the data|analysed the data|wrote the first draft	designed the study	Conceived and designed the experiments	Methodology	YES
5898226	29652098	LFS	PLoS52	designed the study|acquired the data|analysed the data|wrote the first draft	acquired the data	Performed the experiments	Investigation	YES
5898226	29652098	LFS	PLoS52	designed the study|acquired the data|analysed the data|wrote the first draft	analysed the data	Analyzed the data	Formal analysis	YES
5898226	29652098	LFS	PLoS52	designed the study|acquired the data|analysed the data|wrote the first draft	wrote the first draft	Wrote the paper	Writing - Original Draft	YES
5898226	29652098	NH	PLoS52	acquired the data	acquired the data	Performed the experiments	Investigation	YES
5898226	29652098	OA	PLoS52	acquired the data|analysed the data	acquired the data	Performed the experiments	Investigation	YES
5898226	29652098	OA	PLoS52	acquired the data|analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
5898226	29652098	PV	PLoS52	acquired the data	acquired the data	Performed the experiments	Investigation	YES
4409148	25910186	DS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4409148	25910186	DS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409148	25910186	EHS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4409148	25910186	EHS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409148	25910186	HJF	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409148	25910186	HJF	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409148	25910186	HJMH	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409148	25910186	HJMH	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409148	25910186	HK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409148	25910186	HK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409148	25910186	HK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409148	25910186	HK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409148	25910186	JMW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409148	25910186	JMW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409148	25910186	JMW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409148	25910186	JNS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409148	25910186	JNS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409148	25910186	JNS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409148	25910186	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409148	25910186	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409148	25910186	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409148	25910186	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409148	25910186	MTK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409148	25910186	MTK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409148	25910186	MTK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409148	25910186	MTK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409148	25910186	OR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409148	25910186	OR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409148	25910186	OR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409148	25910186	OR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409148	25910186	SHD	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409148	25910186	SHD	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409148	25910186	TH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409148	25910186	TH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4409148	25910186	TH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5622300	28993788	JW	PLoS52	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5622300	28993788	JX	PLoS52	conceived the study and designed the experiments|analyzed the data|wrote the manuscript	conceived the study and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5622300	28993788	JX	PLoS52	conceived the study and designed the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5622300	28993788	JX	PLoS52	conceived the study and designed the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5622300	28993788	LS	PLoS52	carried out the experiments|analyzed the data|wrote the manuscript	carried out the experiments	Performed the experiments	Investigation	YES
5622300	28993788	LS	PLoS52	carried out the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5622300	28993788	LS	PLoS52	carried out the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5622300	28993788	PZ	PLoS52	carried out the experiments|analyzed the data	carried out the experiments	Performed the experiments	Investigation	YES
5622300	28993788	PZ	PLoS52	carried out the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5622300	28993788	RW	PLoS52	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5622300	28993788	YL	PLoS52	carried out the experiments|analyzed the data|wrote the manuscript	carried out the experiments	Performed the experiments	Investigation	YES
5622300	28993788	YL	PLoS52	carried out the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5622300	28993788	YL	PLoS52	carried out the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
1762415	17205117	AA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762415	17205117	AA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762415	17205117	AA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762415	17205117	AA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762415	17205117	EK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762415	17205117	EK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762415	17205117	EK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762415	17205117	EK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762415	17205117	YK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762415	17205117	YK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762415	17205117	YK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5429560	28499417	FD	PLoS52	performed the experiments|contributed analysis tools	performed the experiments	Performed the experiments	Investigation	YES
5429560	28499417	FD	PLoS52	performed the experiments|contributed analysis tools	contributed analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5429560	28499417	FS	PLoS52	conceived and designed the research|performed english editing	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5429560	28499417	FS	PLoS52	conceived and designed the research|performed english editing	performed english editing	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5429560	28499417	RY	PLoS52	performed the experiments|contributed analysis tools	performed the experiments	Performed the experiments	Investigation	YES
5429560	28499417	RY	PLoS52	performed the experiments|contributed analysis tools	contributed analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5429560	28499417	WW	PLoS52	conceived and designed the research|performed the experiments|analyzed the data and prepared figures|wrote the manuscript	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5429560	28499417	WW	PLoS52	conceived and designed the research|performed the experiments|analyzed the data and prepared figures|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5429560	28499417	WW	PLoS52	conceived and designed the research|performed the experiments|analyzed the data and prepared figures|wrote the manuscript	analyzed the data and prepared figures	Analyzed the data	Formal analysis|Visualization	YES
5429560	28499417	WW	PLoS52	conceived and designed the research|performed the experiments|analyzed the data and prepared figures|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5429560	28499417	XZ	PLoS52	performed the experiments|analyzed the data and prepared figures|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5429560	28499417	XZ	PLoS52	performed the experiments|analyzed the data and prepared figures|wrote the manuscript	analyzed the data and prepared figures	Analyzed the data	Formal analysis|Visualization	YES
5429560	28499417	XZ	PLoS52	performed the experiments|analyzed the data and prepared figures|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5429560	28499417	all authors	PLoS52	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
3506567	23006939	All authors	2	contributed to the scientific and intellectual discussion	contributed to the scientific and intellectual discussion	-	-	NO
3506567	23006939	EFA	2	planned the dosimetric study|made the analysis and interpretation of the data	planned the dosimetric study	Conceived and designed the experiments	Conceptualization	YES
3506567	23006939	EFA	2	planned the dosimetric study|made the analysis and interpretation of the data	made the analysis and interpretation of the data	Analyzed the data	Formal analysis	YES
3506567	23006939	ML	2	planned the dosimetric study|performed the calibrations, image analyses, and the first compilation of the data|made the analysis and interpretation of the data|drafted the manuscript	planned the dosimetric study	Conceived and designed the experiments	Conceptualization	YES
3506567	23006939	ML	2	planned the dosimetric study|performed the calibrations, image analyses, and the first compilation of the data|made the analysis and interpretation of the data|drafted the manuscript	performed the calibrations, image analyses, and the first compilation of the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
3506567	23006939	ML	2	planned the dosimetric study|performed the calibrations, image analyses, and the first compilation of the data|made the analysis and interpretation of the data|drafted the manuscript	made the analysis and interpretation of the data	Analyzed the data	Formal analysis	YES
3506567	23006939	ML	2	planned the dosimetric study|performed the calibrations, image analyses, and the first compilation of the data|made the analysis and interpretation of the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
3506567	23006939	PB	2	planned the dosimetric study	planned the dosimetric study	Conceived and designed the experiments	Conceptualization	YES
4409150	25909909	CYLC	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409150	25909909	FY	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409150	25909909	GY	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409150	25909909	IA	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409150	25909909	KHT	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409150	25909909	KK	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409150	25909909	KK	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409150	25909909	KMG	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409150	25909909	LJL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409150	25909909	LJL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409150	25909909	LJL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409150	25909909	LJL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409150	25909909	LLS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409150	25909909	LLS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409150	25909909	LLS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409150	25909909	LLS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409150	25909909	MKI	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409150	25909909	MTT	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409150	25909909	MTT	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409150	25909909	PG	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409150	25909909	SMS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409150	25909909	SMS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409150	25909909	TYW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409150	25909909	TYW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409150	25909909	TYW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409150	25909909	YSC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409150	25909909	YSC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409150	25909909	YSC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409150	25909909	YSL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409150	25909909	YSL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409150	25909909	YSL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3508867	22818866	EJ	2	participated in the design of the rw algorithm	participated in the design of the rw algorithm	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
3508867	22818866	PV	2	conceived of the study, and participated in its design and coordination	conceived of the study, and participated in its design and coordination	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
3508867	22818866	RM	2	drafted the manuscript, designed the phantom and patient study and performed the statistical analysis	drafted the manuscript, designed the phantom and patient study and performed the statistical analysis	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3508867	22818866	TL	2	participated in the design of the rw algorithm	participated in the design of the rw algorithm	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
1762416	17205133	AG	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Analyzed the data|Wrote the paper|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762416	17205133	AG	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Analyzed the data|Wrote the paper|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762416	17205133	AG	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Analyzed the data|Wrote the paper|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762416	17205133	AG	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Analyzed the data|Wrote the paper|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762416	17205133	AG	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Analyzed the data|Wrote the paper|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762416	17205133	AP	PLoS5	Conceived and designed the experiments|Performed the experiments|Collected the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762416	17205133	AP	PLoS5	Conceived and designed the experiments|Performed the experiments|Collected the data	Performed the experiments	Performed the experiments	Investigation	YES
1762416	17205133	AP	PLoS5	Conceived and designed the experiments|Performed the experiments|Collected the data	Collected the data	Performed the experiments	Investigation	YES
1762416	17205133	BR	PLoS5	Contributed reagents/materials/analysis tools|Collected human samples	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762416	17205133	BR	PLoS5	Contributed reagents/materials/analysis tools|Collected human samples	Collected human samples	Performed the experiments	Investigation	YES
1762416	17205133	GB	PLoS5	Performed the experiments|Collected the data	Performed the experiments	Performed the experiments	Investigation	YES
1762416	17205133	GB	PLoS5	Performed the experiments|Collected the data	Collected the data	Performed the experiments	Investigation	YES
1762416	17205133	GW	PLoS5	Contributed reagents/materials/analysis tools|Collected human samples	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762416	17205133	GW	PLoS5	Contributed reagents/materials/analysis tools|Collected human samples	Collected human samples	Performed the experiments	Investigation	YES
1762416	17205133	JT	PLoS5	Contributed reagents/materials/analysis tools|Collected human samples	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762416	17205133	JT	PLoS5	Contributed reagents/materials/analysis tools|Collected human samples	Collected human samples	Performed the experiments	Investigation	YES
1762416	17205133	KW	PLoS5	Performed the experiments|Collected the data	Performed the experiments	Performed the experiments	Investigation	YES
1762416	17205133	KW	PLoS5	Performed the experiments|Collected the data	Collected the data	Performed the experiments	Investigation	YES
1762416	17205133	RH	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762416	17205133	SC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Collected the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762416	17205133	SC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Collected the data	Performed the experiments	Performed the experiments	Investigation	YES
1762416	17205133	SC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Collected the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762416	17205133	SC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Collected the data	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762416	17205133	SC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Collected the data	Collected the data	Performed the experiments	Investigation	YES
1762416	17205133	TE	PLoS5	Performed the experiments|Collected the data	Performed the experiments	Performed the experiments	Investigation	YES
1762416	17205133	TE	PLoS5	Performed the experiments|Collected the data	Collected the data	Performed the experiments	Investigation	YES
5904528	29667336	AC	2	were responsible for the design of this research as well as the writing/revision of this manuscript	were responsible for the design of this research as well as the writing/revision of this manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5904528	29667336	BE	2	were instrumental in the writing and revision of this manuscript	were instrumental in the writing and revision of this manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5904528	29667336	DM	2	were responsible for the design of this research as well as the writing/revision of this manuscript	were responsible for the design of this research as well as the writing/revision of this manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5904528	29667336	FD	2	were instrumental in the writing and revision of this manuscript	were instrumental in the writing and revision of this manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5904528	29667336	KAF	2	were instrumental in the writing and revision of this manuscript	were instrumental in the writing and revision of this manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5904528	29667336	NR	2	were instrumental in the writing and revision of this manuscript	were instrumental in the writing and revision of this manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5904528	29667336	RLL	2	were responsible for the design of this research as well as the writing/revision of this manuscript	were responsible for the design of this research as well as the writing/revision of this manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5904528	29667336	RS	2	were instrumental in the writing and revision of this manuscript	were instrumental in the writing and revision of this manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5904528	29667336	RW	2	were instrumental in the writing and revision of this manuscript	were instrumental in the writing and revision of this manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5904528	29667336	SL	2	were instrumental in the writing and revision of this manuscript	were instrumental in the writing and revision of this manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5904528	29667336	VL	2	were instrumental in the writing and revision of this manuscript	were instrumental in the writing and revision of this manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5622589	28993784	AS	2	conducted some experiments	conducted some experiments	Performed the experiments	Investigation	YES
5622589	28993784	All the authors	2	read and approved the manuscript	read and approved the manuscript	-	-	NO
5622589	28993784	DP	2	performed most of the experiments	performed most of the experiments	Performed the experiments	Investigation	YES
5622589	28993784	EkVS	2	performed most of the experiments|evaluated the data and drafted the skeleton of manuscript|revised and finalized the manuscript	performed most of the experiments	Performed the experiments	Investigation	YES
5622589	28993784	EkVS	2	performed most of the experiments|evaluated the data and drafted the skeleton of manuscript|revised and finalized the manuscript	evaluated the data and drafted the skeleton of manuscript	Wrote the paper	Writing - Original Draft	YES
5622589	28993784	EkVS	2	performed most of the experiments|evaluated the data and drafted the skeleton of manuscript|revised and finalized the manuscript	revised and finalized the manuscript	Wrote the paper	Writing - Review & Editing	YES
5622589	28993784	EuVS	2	conducted some experiments	conducted some experiments	Performed the experiments	Investigation	YES
5622589	28993784	NE	2	conducted some experiments	conducted some experiments	Performed the experiments	Investigation	YES
5622589	28993784	TK	2	conceptualized the topic and designed the experiments|conducted some experiments|evaluated the data and drafted the skeleton of manuscript|revised and finalized the manuscript	conceptualized the topic and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5622589	28993784	TK	2	conceptualized the topic and designed the experiments|conducted some experiments|evaluated the data and drafted the skeleton of manuscript|revised and finalized the manuscript	conducted some experiments	Performed the experiments	Investigation	YES
5622589	28993784	TK	2	conceptualized the topic and designed the experiments|conducted some experiments|evaluated the data and drafted the skeleton of manuscript|revised and finalized the manuscript	evaluated the data and drafted the skeleton of manuscript	Wrote the paper	Writing - Original Draft	YES
5622589	28993784	TK	2	conceptualized the topic and designed the experiments|conducted some experiments|evaluated the data and drafted the skeleton of manuscript|revised and finalized the manuscript	revised and finalized the manuscript	Wrote the paper	Writing - Review & Editing	YES
5622589	28993784	VT	2	conducted some experiments	conducted some experiments	Performed the experiments	Investigation	YES
5622589	28993784	YD	2	conceptualized the topic and designed the experiments|evaluated the data and drafted the skeleton of manuscript|revised and finalized the manuscript	conceptualized the topic and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5622589	28993784	YD	2	conceptualized the topic and designed the experiments|evaluated the data and drafted the skeleton of manuscript|revised and finalized the manuscript	evaluated the data and drafted the skeleton of manuscript	Wrote the paper	Writing - Original Draft	YES
5622589	28993784	YD	2	conceptualized the topic and designed the experiments|evaluated the data and drafted the skeleton of manuscript|revised and finalized the manuscript	revised and finalized the manuscript	Wrote the paper	Writing - Review & Editing	YES
5429574	28499350	QL	2	conceived the project|developed the algorithm|performed experiments	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5429574	28499350	QL	2	conceived the project|developed the algorithm|performed experiments	developed the algorithm	Contributed reagents/materials/analysis tools	Software	YES
5429574	28499350	QL	2	conceived the project|developed the algorithm|performed experiments	performed experiments	Performed the experiments	Investigation	YES
5429574	28499350	RB	2	developed the algorithm	developed the algorithm	Contributed reagents/materials/analysis tools	Software	YES
5429574	28499350	TL	2	developed the algorithm|performed experiments	developed the algorithm	Contributed reagents/materials/analysis tools	Software	YES
5429574	28499350	TL	2	developed the algorithm|performed experiments	performed experiments	Performed the experiments	Investigation	YES
5429574	28499350	VXJ	2	conceived the project	conceived the project	Conceived and designed the experiments	Conceptualization	YES
4409151	25909636	CS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409151	25909636	CS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409151	25909636	CS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409151	25909636	CS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409151	25909636	EW	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409151	25909636	EW	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409151	25909636	JM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409151	25909636	KK	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409151	25909636	KK	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409151	25909636	KN	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409151	25909636	LE	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409151	25909636	LE	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409151	25909636	LE	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409151	25909636	PE	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409151	25909636	PE	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3508933	23140372	FB	2	participated in the design and coordination of the study and helped draft and correct the manuscript	participated in the design and coordination of the study and helped draft and correct the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft|Writing - Review & Editing	YES
3508933	23140372	MP	2	laid out the study design, carried out the experimental procedures, performed the statistical analysis, and drafted the report	laid out the study design, carried out the experimental procedures, performed the statistical analysis, and drafted the report	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
3508933	23140372	RL	2	participated in the design and coordination of the study and helped draft and correct the manuscript	participated in the design and coordination of the study and helped draft and correct the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft|Writing - Review & Editing	YES
5622593	28993782	LG	2	revised manuscript for publication	revised manuscript for publication	Wrote the paper	Writing - Review & Editing	YES
3511205	23107475	AAR	PLoS52	designed the study, analyzed and interpreted the data, and wrote the manuscript	designed the study, analyzed and interpreted the data, and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3511205	23107475	ASS	PLoS52	designed the study, analyzed and interpreted the data, and wrote the manuscript	designed the study, analyzed and interpreted the data, and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3511205	23107475	EK	PLoS52	designed the study, performed the experiments, analyzed and interpreted the data, and wrote the manuscript	designed the study, performed the experiments, analyzed and interpreted the data, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
3511205	23107475	GV	PLoS52	designed the study, analyzed and interpreted the data, and wrote the manuscript	designed the study, analyzed and interpreted the data, and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3511205	23107475	MRZ	PLoS52	designed the study, analyzed and interpreted the data, and wrote the manuscript	designed the study, analyzed and interpreted the data, and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3511205	23107475	TAS	PLoS52	designed the study, performed the experiments, analyzed and interpreted the data, and drafted and wrote the manuscript	designed the study, performed the experiments, analyzed and interpreted the data, and drafted and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
3511205	23107475	TNL	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
1762417	17205136	RJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762417	17205136	RJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762417	17205136	RJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762417	17205136	RJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762417	17205136	XN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762417	17205136	XN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762417	17205136	XN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762417	17205136	XN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5429582	28499347	DGEP	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5429582	28499347	IMV	PLoS52	performed the microscopy analysis	performed the microscopy analysis	Performed the experiments	Investigation	YES
5429582	28499347	MvH	PLoS52	analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5429582	28499347	MvH	PLoS52	analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5429582	28499347	PDM	PLoS52	guided bioinformatic data analysis|analyzed the data|wrote the paper	guided bioinformatic data analysis	Analyzed the data	Formal analysis|Supervision	YES
5429582	28499347	PDM	PLoS52	guided bioinformatic data analysis|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5429582	28499347	PDM	PLoS52	guided bioinformatic data analysis|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5429582	28499347	PJV	PLoS52	conceived and designed the experiments|analyzed the data|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5429582	28499347	PJV	PLoS52	conceived and designed the experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5429582	28499347	PJV	PLoS52	conceived and designed the experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5429582	28499347	WCdL	PLoS52	performed the microscopy analysis	performed the microscopy analysis	Performed the experiments	Investigation	YES
5429582	28499347	WMCvR	PLoS52	gave critical suggestions specially focused on the hd field	gave critical suggestions specially focused on the hd field	-	-	NO
4409171	25910080	HYJ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409171	25910080	LZ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409171	25910080	QW	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409171	25910080	RX	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409171	25910080	SQW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409171	25910080	SQW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409171	25910080	SQW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409171	25910080	SQW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409171	25910080	SQW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409171	25910080	X. Zhao	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409171	25910080	X. Zhao	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409171	25910080	X. Zhu	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
3519614	23021250	AU	2	were involved in conceiving the study and revising the manuscript	were involved in conceiving the study and revising the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
3519614	23021250	CT	2	experiments, participated in the design of the study, and drafted the manuscript	experiments, participated in the design of the study, and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3519614	23021250	EH	2	carried out the data analysis and template creation	carried out the data analysis and template creation	Analyzed the data	Formal analysis	YES
3519614	23021250	J-OA	2	involved in conceiving the study and provided the animals	involved in conceiving the study and provided the animals	Conceived and designed the experiments	Conceptualization	YES
3519614	23021250	KB	2	conceived the study, participated in its design and coordination, and helped draft the manuscript	conceived the study, participated in its design and coordination, and helped draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
3519614	23021250	MP	2	carried out the data analysis and template creation	carried out the data analysis and template creation	Analyzed the data	Formal analysis	YES
3519614	23021250	MS	2	involved in conceiving the study and provided the animals	involved in conceiving the study and provided the animals	Conceived and designed the experiments	Conceptualization	YES
3519614	23021250	PTM	2	were involved in conceiving the study and revising the manuscript	were involved in conceiving the study and revising the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
3519614	23021250	SS	2	were involved in conceiving the study and revising the manuscript	were involved in conceiving the study and revising the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5622609	28993783	All authors	2	reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5622609	28993783	FY	2	conceived and designed the study|performed data analysis and prepared tables and figures|drafted the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5622609	28993783	FY	2	conceived and designed the study|performed data analysis and prepared tables and figures|drafted the manuscript	performed data analysis and prepared tables and figures	Analyzed the data	Formal analysis|Visualization	YES
5622609	28993783	FY	2	conceived and designed the study|performed data analysis and prepared tables and figures|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5622609	28993783	GJ	2	performed data analysis and prepared tables and figures	performed data analysis and prepared tables and figures	Analyzed the data	Formal analysis|Visualization	YES
5622609	28993783	HB	2	conceived and designed the study|implemented field trials and performed the phenotyping	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5622609	28993783	HB	2	conceived and designed the study|implemented field trials and performed the phenotyping	implemented field trials and performed the phenotyping	Performed the experiments	Investigation	YES
5622609	28993783	JX	2	performed data analysis and prepared tables and figures|drafted the manuscript	performed data analysis and prepared tables and figures	Analyzed the data	Formal analysis|Visualization	YES
5622609	28993783	JX	2	performed data analysis and prepared tables and figures|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5622609	28993783	KR	2	conceived and designed the study|implemented field trials and performed the phenotyping	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5622609	28993783	KR	2	conceived and designed the study|implemented field trials and performed the phenotyping	implemented field trials and performed the phenotyping	Performed the experiments	Investigation	YES
5622609	28993783	SC	2	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5622609	28993783	SD	2	conceived and designed the study|implemented field trials and performed the phenotyping	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5622609	28993783	SD	2	conceived and designed the study|implemented field trials and performed the phenotyping	implemented field trials and performed the phenotyping	Performed the experiments	Investigation	YES
1762418	17205119	AR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762418	17205119	AR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762418	17205119	AR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762418	17205119	AR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762418	17205119	KD	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762418	17205119	MP	PLoS5	Contributed reagents/materials/analysis tools|Suggested corrections to the manuscript before submission	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762418	17205119	MP	PLoS5	Contributed reagents/materials/analysis tools|Suggested corrections to the manuscript before submission	Suggested corrections to the manuscript before submission	Wrote the paper	Writing - Review & Editing	YES
1762418	17205119	RJ	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762418	17205119	SA	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762418	17205119	SA	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762418	17205119	YS	PLoS5	Contributed reagents/materials/analysis tools|Corrected the paper before submission	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762418	17205119	YS	PLoS5	Contributed reagents/materials/analysis tools|Corrected the paper before submission	Corrected the paper before submission	Wrote the paper	Writing - Review & Editing	YES
3519726	23009555	GAMSvD	PLoS52	designed the experiments|have written the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
3519726	23009555	GAMSvD	PLoS52	designed the experiments|have written the manuscript	have written the manuscript	Wrote the paper	Writing - Original Draft	YES
3519726	23009555	MSvW	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
3519726	23009555	PMPvB	PLoS52	designed the experiments|have written the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
3519726	23009555	PMPvB	PLoS52	designed the experiments|have written the manuscript	have written the manuscript	Wrote the paper	Writing - Original Draft	YES
3519726	23009555	PvD	PLoS52	participated in important discussions	participated in important discussions	-	-	NO
3519726	23009555	RC	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
3519726	23009555	SO	PLoS52	designed the experiments|performed the experiments|have written the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
3519726	23009555	SO	PLoS52	designed the experiments|performed the experiments|have written the manuscript	performed the experiments	Performed the experiments	Investigation	YES
3519726	23009555	SO	PLoS52	designed the experiments|performed the experiments|have written the manuscript	have written the manuscript	Wrote the paper	Writing - Original Draft	YES
3519726	23009555	WM	PLoS52	participated in important discussions	participated in important discussions	-	-	NO
4409172	25909847	BM	PLoS5	Data collection of clinical samples	Data collection of clinical samples	Performed the experiments	Investigation	YES
4409172	25909847	EP	PLoS5	Wrote the paper|Data collection of clinical samples	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409172	25909847	EP	PLoS5	Wrote the paper|Data collection of clinical samples	Data collection of clinical samples	Performed the experiments	Investigation	YES
4409172	25909847	ES	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409172	25909847	FS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409172	25909847	JP	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409172	25909847	JP	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409172	25909847	JTR	PLoS5	Data collection of clinical samples	Data collection of clinical samples	Performed the experiments	Investigation	YES
4409172	25909847	KD	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409172	25909847	KD	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409172	25909847	MD	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409172	25909847	NR	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409172	25909847	PVH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409172	25909847	RW	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409172	25909847	RW	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409172	25909847	RW	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5622955	29018474	CW	2	conceived the ideas|performed the analysis|wrote the first draft	conceived the ideas	Conceived and designed the experiments	Conceptualization	YES
5622955	29018474	CW	2	conceived the ideas|performed the analysis|wrote the first draft	performed the analysis	Performed the experiments	Investigation	YES
5622955	29018474	CW	2	conceived the ideas|performed the analysis|wrote the first draft	wrote the first draft	Wrote the paper	Writing - Original Draft	YES
5622955	29018474	DJ	2	collected the data	collected the data	Performed the experiments	Investigation	YES
5622955	29018474	JL	2	performed the analysis	performed the analysis	Performed the experiments	Investigation	YES
5622955	29018474	ML	2	led the writing of the manuscript	led the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5622955	29018474	SS	2	collected the data	collected the data	Performed the experiments	Investigation	YES
5622955	29018474	TZ	2	led the writing of the manuscript	led the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5622955	29018474	WG	2	led the writing of the manuscript	led the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5622955	29018474	YC	2	led the writing of the manuscript	led the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5622955	29018474	ZC	2	collected the data	collected the data	Performed the experiments	Investigation	YES
5622955	29018474	ZG	2	collected the data	collected the data	Performed the experiments	Investigation	YES
5909111	29676000	AG	2	counceptualized the study and data analysis plan|drafted the manuscript	counceptualized the study and data analysis plan	Analyzed the data	Formal analysis	YES
5909111	29676000	AG	2	counceptualized the study and data analysis plan|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5909111	29676000	AK	2	reviewed and commented on initial and final drafts of the manuscript	reviewed and commented on initial and final drafts of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5909111	29676000	BT	2	extracted and collected data|performed the data analysis	extracted and collected data	Performed the experiments	Investigation	YES
5909111	29676000	BT	2	extracted and collected data|performed the data analysis	performed the data analysis	Analyzed the data	Formal analysis	YES
5909111	29676000	BW	2	reviewed and commented on initial and final drafts of the manuscript	reviewed and commented on initial and final drafts of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5909111	29676000	CS	2	extracted and collected data|reviewed and commented on initial and final drafts of the manuscript	extracted and collected data	Performed the experiments	Investigation	YES
5909111	29676000	CS	2	extracted and collected data|reviewed and commented on initial and final drafts of the manuscript	reviewed and commented on initial and final drafts of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5909111	29676000	DAC	2	reviewed and commented on initial and final drafts of the manuscript	reviewed and commented on initial and final drafts of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5909111	29676000	DC	2	extracted and collected data|performed the data analysis	extracted and collected data	Performed the experiments	Investigation	YES
5909111	29676000	DC	2	extracted and collected data|performed the data analysis	performed the data analysis	Analyzed the data	Formal analysis	YES
5909111	29676000	DPW	2	reviewed and commented on initial and final drafts of the manuscript	reviewed and commented on initial and final drafts of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5909111	29676000	H-MS	2	extracted and collected data|reviewed and commented on initial and final drafts of the manuscript	extracted and collected data	Performed the experiments	Investigation	YES
5909111	29676000	H-MS	2	extracted and collected data|reviewed and commented on initial and final drafts of the manuscript	reviewed and commented on initial and final drafts of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5909111	29676000	JH	2	extracted and collected data	extracted and collected data	Performed the experiments	Investigation	YES
5909111	29676000	MH	2	reviewed and commented on initial and final drafts of the manuscript	reviewed and commented on initial and final drafts of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5909111	29676000	PK	2	counceptualized the study and data analysis plan|drafted the manuscript	counceptualized the study and data analysis plan	Analyzed the data	Formal analysis	YES
5909111	29676000	PK	2	counceptualized the study and data analysis plan|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5909111	29676000	RG	2	counceptualized the study and data analysis plan|extracted and collected data|performed the data analysis|reviewed and commented on initial and final drafts of the manuscript	counceptualized the study and data analysis plan	Analyzed the data	Formal analysis	YES
5909111	29676000	RG	2	counceptualized the study and data analysis plan|extracted and collected data|performed the data analysis|reviewed and commented on initial and final drafts of the manuscript	extracted and collected data	Performed the experiments	Investigation	YES
5909111	29676000	RG	2	counceptualized the study and data analysis plan|extracted and collected data|performed the data analysis|reviewed and commented on initial and final drafts of the manuscript	performed the data analysis	Analyzed the data	Formal analysis	YES
5909111	29676000	RG	2	counceptualized the study and data analysis plan|extracted and collected data|performed the data analysis|reviewed and commented on initial and final drafts of the manuscript	reviewed and commented on initial and final drafts of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5909111	29676000	RTG	2	counceptualized the study and data analysis plan|performed the data analysis|drafted the manuscript	counceptualized the study and data analysis plan	Analyzed the data	Formal analysis	YES
5909111	29676000	RTG	2	counceptualized the study and data analysis plan|performed the data analysis|drafted the manuscript	performed the data analysis	Analyzed the data	Formal analysis	YES
5909111	29676000	RTG	2	counceptualized the study and data analysis plan|performed the data analysis|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
1762419	17205138	JR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762419	17205138	JR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762419	17205138	JR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762419	17205138	JR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762419	17205138	NH	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762419	17205138	NH	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762419	17205138	TA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762419	17205138	TA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762419	17205138	TA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762419	17205138	TA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5430618	28506246	HH	2	conceptualized and initiate the project|drafted the paper|supervised the project	conceptualized and initiate the project	Conceived and designed the experiments	Conceptualization	YES
5430618	28506246	HH	2	conceptualized and initiate the project|drafted the paper|supervised the project	drafted the paper	Wrote the paper	Writing - Original Draft	YES
5430618	28506246	HH	2	conceptualized and initiate the project|drafted the paper|supervised the project	supervised the project	-	Supervision	YES
5430618	28506246	JL	2	conceptualized and initiate the project|drafted the paper	conceptualized and initiate the project	Conceived and designed the experiments	Conceptualization	YES
5430618	28506246	JL	2	conceptualized and initiate the project|drafted the paper	drafted the paper	Wrote the paper	Writing - Original Draft	YES
5430618	28506246	MN	2	drafted the paper|supervised the project	drafted the paper	Wrote the paper	Writing - Original Draft	YES
5430618	28506246	MN	2	drafted the paper|supervised the project	supervised the project	-	Supervision	YES
5430618	28506246	OC	2	conceptualized and initiate the project|drafted the paper|supervised the project	conceptualized and initiate the project	Conceived and designed the experiments	Conceptualization	YES
5430618	28506246	OC	2	conceptualized and initiate the project|drafted the paper|supervised the project	drafted the paper	Wrote the paper	Writing - Original Draft	YES
5430618	28506246	OC	2	conceptualized and initiate the project|drafted the paper|supervised the project	supervised the project	-	Supervision	YES
3520720	23157877	ABC	2	contributed to the study design and data interpretation, and recruited appropriate patients to the study	contributed to the study design and data interpretation, and recruited appropriate patients to the study	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Methodology|Resources	YES
3520720	23157877	All authors	2	reviewed and provided feedback and insights for further research	reviewed and provided feedback and insights for further research	-	-	NO
3520720	23157877	DD	2	contributed to the study design, provided guidance on data analysis, and contributed to the writing of the manuscript	contributed to the study design, provided guidance on data analysis, and contributed to the writing of the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Supervision|Writing - Original Draft	YES
3520720	23157877	IM	2	contributed to the study design and data interpretation, and recruited appropriate patients to the study	contributed to the study design and data interpretation, and recruited appropriate patients to the study	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Methodology|Resources	YES
3520720	23157877	JF	2	contributed to the study design and assisted lra in all aspects of data collection	contributed to the study design and assisted lra in all aspects of data collection	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources	YES
3520720	23157877	LRA	2	contributed to the study design and collected all data in the manuscript	contributed to the study design and collected all data in the manuscript	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources	YES
3520720	23157877	RGA	2	contributed to the study design, performed data interpretation, and contributed substantially to the writing of the manuscript	contributed to the study design, performed data interpretation, and contributed substantially to the writing of the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Original Draft	YES
3520720	23157877	TEY	2	was the primary investigator responsible for the experimental design, intellectual content, supervision of data collection and analysis, and writing/editing the manuscript	was the primary investigator responsible for the experimental design, intellectual content, supervision of data collection and analysis, and writing/editing the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
3520720	23157877	VA	2	contributed to the study design and data interpretation, and recruited appropriate patients to the study	contributed to the study design and data interpretation, and recruited appropriate patients to the study	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Methodology|Resources	YES
3520720	23157877	XL	2	contributed to the study design, performed data analysis, and is the primary author of the manuscript	contributed to the study design, performed data analysis, and is the primary author of the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Original Draft	YES
4409204	25909443	AM	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409204	25909443	HAS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409204	25909443	HAS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409204	25909443	HAS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409204	25909443	HAS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409204	25909443	JTH	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409204	25909443	JWT	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409204	25909443	JWT	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409204	25909443	JWT	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409204	25909443	LGD	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409204	25909443	RHV	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409204	25909443	RHV	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409204	25909443	RHV	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409204	25909443	YSC	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4409204	25909443	YSC	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762420	17205121	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762420	17205121	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762420	17205121	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762420	17205121	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762420	17205121	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762420	17205121	PH	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Wrote the paper|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762420	17205121	PH	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Wrote the paper|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762420	17205121	PH	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Wrote the paper|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762420	17205121	PH	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Wrote the paper|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762420	17205121	PH	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Wrote the paper|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762420	17205121	PH	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Wrote the paper|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762420	17205121	PH	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Wrote the paper|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762420	17205121	PH	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Wrote the paper|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762420	17205121	SV	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762420	17205121	SV	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762420	17205121	SV	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762420	17205121	TT	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762420	17205121	TT	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5909112	29675995	CO	2	conceived the study design and research question|oversaw study implementation and data collation	conceived the study design and research question	Conceived and designed the experiments	Conceptualization|Methodology	YES
5909112	29675995	CO	2	conceived the study design and research question|oversaw study implementation and data collation	oversaw study implementation and data collation	Performed the experiments	Investigation|Supervision	YES
5909112	29675995	DO	2	oversaw study implementation and data collation|provided critical reviews of all draft versions of the manuscript	oversaw study implementation and data collation	Performed the experiments	Investigation|Supervision	YES
5909112	29675995	DO	2	oversaw study implementation and data collation|provided critical reviews of all draft versions of the manuscript	provided critical reviews of all draft versions of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5909112	29675995	EAO	2	conceived the study design and research question|developed the protocol|oversaw study implementation and data collation|provided critical reviews of all draft versions of the manuscript|assisted with conducting data analysis, data interpretation and critical review of the manuscript	conceived the study design and research question	Conceived and designed the experiments	Conceptualization|Methodology	YES
5909112	29675995	EAO	2	conceived the study design and research question|developed the protocol|oversaw study implementation and data collation|provided critical reviews of all draft versions of the manuscript|assisted with conducting data analysis, data interpretation and critical review of the manuscript	developed the protocol	Conceived and designed the experiments	Methodology	YES
5909112	29675995	EAO	2	conceived the study design and research question|developed the protocol|oversaw study implementation and data collation|provided critical reviews of all draft versions of the manuscript|assisted with conducting data analysis, data interpretation and critical review of the manuscript	oversaw study implementation and data collation	Performed the experiments	Investigation|Supervision	YES
5909112	29675995	EAO	2	conceived the study design and research question|developed the protocol|oversaw study implementation and data collation|provided critical reviews of all draft versions of the manuscript|assisted with conducting data analysis, data interpretation and critical review of the manuscript	provided critical reviews of all draft versions of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5909112	29675995	EAO	2	conceived the study design and research question|developed the protocol|oversaw study implementation and data collation|provided critical reviews of all draft versions of the manuscript|assisted with conducting data analysis, data interpretation and critical review of the manuscript	assisted with conducting data analysis, data interpretation and critical review of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5909112	29675995	EJ	2	provided critical reviews of all draft versions of the manuscript|provided critical reviews of all drafts	provided critical reviews of all draft versions of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5909112	29675995	EJ	2	provided critical reviews of all draft versions of the manuscript|provided critical reviews of all drafts	provided critical reviews of all drafts	Wrote the paper	Writing - Original Draft	YES
5909112	29675995	EO	2	provided critical reviews of all draft versions of the manuscript|provided critical reviews of all drafts	provided critical reviews of all draft versions of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5909112	29675995	EO	2	provided critical reviews of all draft versions of the manuscript|provided critical reviews of all drafts	provided critical reviews of all drafts	Wrote the paper	Writing - Original Draft	YES
5909112	29675995	GO	2	oversaw study implementation and data collation	oversaw study implementation and data collation	Performed the experiments	Investigation|Supervision	YES
5909112	29675995	HK	2	conceived the study design and research question|oversaw study implementation and data collation|provided critical reviews of all drafts|assisted with conducting data analysis, data interpretation and critical review of the manuscript	conceived the study design and research question	Conceived and designed the experiments	Conceptualization|Methodology	YES
5909112	29675995	HK	2	conceived the study design and research question|oversaw study implementation and data collation|provided critical reviews of all drafts|assisted with conducting data analysis, data interpretation and critical review of the manuscript	oversaw study implementation and data collation	Performed the experiments	Investigation|Supervision	YES
5909112	29675995	HK	2	conceived the study design and research question|oversaw study implementation and data collation|provided critical reviews of all drafts|assisted with conducting data analysis, data interpretation and critical review of the manuscript	provided critical reviews of all drafts	Wrote the paper	Writing - Original Draft	YES
5909112	29675995	HK	2	conceived the study design and research question|oversaw study implementation and data collation|provided critical reviews of all drafts|assisted with conducting data analysis, data interpretation and critical review of the manuscript	assisted with conducting data analysis, data interpretation and critical review of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5909112	29675995	KT	2	conceived the study design and research question|provided critical reviews of all drafts|assisted with conducting data analysis, data interpretation and critical review of the manuscript	conceived the study design and research question	Conceived and designed the experiments	Conceptualization|Methodology	YES
5909112	29675995	KT	2	conceived the study design and research question|provided critical reviews of all drafts|assisted with conducting data analysis, data interpretation and critical review of the manuscript	provided critical reviews of all drafts	Wrote the paper	Writing - Original Draft	YES
5909112	29675995	KT	2	conceived the study design and research question|provided critical reviews of all drafts|assisted with conducting data analysis, data interpretation and critical review of the manuscript	assisted with conducting data analysis, data interpretation and critical review of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5909112	29675995	MA	2	developed the protocol|oversaw study implementation and data collation|oversaw study implementation and data collation|provided critical reviews of all draft versions of the manuscript	developed the protocol	Conceived and designed the experiments	Methodology	YES
5909112	29675995	MA	2	developed the protocol|oversaw study implementation and data collation|oversaw study implementation and data collation|provided critical reviews of all draft versions of the manuscript	oversaw study implementation and data collation	Performed the experiments	Investigation|Supervision	YES
5909112	29675995	MA	2	developed the protocol|oversaw study implementation and data collation|oversaw study implementation and data collation|provided critical reviews of all draft versions of the manuscript	oversaw study implementation and data collation	Performed the experiments	Investigation|Supervision	YES
5909112	29675995	MA	2	developed the protocol|oversaw study implementation and data collation|oversaw study implementation and data collation|provided critical reviews of all draft versions of the manuscript	provided critical reviews of all draft versions of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5909112	29675995	NO	2	provided critical reviews of all draft versions of the manuscript	provided critical reviews of all draft versions of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5909112	29675995	OAB	2	developed the protocol|conducted the data analysis, literature search and wrote the first draft of the manuscript|provided critical reviews of all draft versions of the manuscript	developed the protocol	Conceived and designed the experiments	Methodology	YES
5909112	29675995	OAB	2	developed the protocol|conducted the data analysis, literature search and wrote the first draft of the manuscript|provided critical reviews of all draft versions of the manuscript	conducted the data analysis, literature search and wrote the first draft of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5909112	29675995	OAB	2	developed the protocol|conducted the data analysis, literature search and wrote the first draft of the manuscript|provided critical reviews of all draft versions of the manuscript	provided critical reviews of all draft versions of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5909112	29675995	OIO	2	oversaw study implementation and data collation|provided critical reviews of all drafts	oversaw study implementation and data collation	Performed the experiments	Investigation|Supervision	YES
5909112	29675995	OIO	2	oversaw study implementation and data collation|provided critical reviews of all drafts	provided critical reviews of all drafts	Wrote the paper	Writing - Original Draft	YES
5909112	29675995	ORNM	2	oversaw study implementation and data collation	oversaw study implementation and data collation	Performed the experiments	Investigation|Supervision	YES
5909112	29675995	SRP	2	provided critical reviews of all drafts|assisted with conducting data analysis, data interpretation and critical review of the manuscript	provided critical reviews of all drafts	Wrote the paper	Writing - Original Draft	YES
5909112	29675995	SRP	2	provided critical reviews of all drafts|assisted with conducting data analysis, data interpretation and critical review of the manuscript	assisted with conducting data analysis, data interpretation and critical review of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5622969	29018469	All authors	2	read and approved the manuscript	read and approved the manuscript	-	-	NO
5622969	29018469	SS	2	initiated and designed the research|obtained funding for this study|collected the materials and performed the experiments|wrote and revised the paper	initiated and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5622969	29018469	SS	2	initiated and designed the research|obtained funding for this study|collected the materials and performed the experiments|wrote and revised the paper	obtained funding for this study	-	Funding acquisition	YES
5622969	29018469	SS	2	initiated and designed the research|obtained funding for this study|collected the materials and performed the experiments|wrote and revised the paper	collected the materials and performed the experiments	Performed the experiments	Investigation	YES
5622969	29018469	SS	2	initiated and designed the research|obtained funding for this study|collected the materials and performed the experiments|wrote and revised the paper	wrote and revised the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5622969	29018469	XZ	2	initiated and designed the research|collected the materials and performed the experiments|wrote and revised the paper	initiated and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5622969	29018469	XZ	2	initiated and designed the research|collected the materials and performed the experiments|wrote and revised the paper	collected the materials and performed the experiments	Performed the experiments	Investigation	YES
5622969	29018469	XZ	2	initiated and designed the research|collected the materials and performed the experiments|wrote and revised the paper	wrote and revised the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5622969	29018469	YW	2	initiated and designed the research	initiated and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5622969	29018469	YZ	2	initiated and designed the research|collected the materials and performed the experiments|wrote and revised the paper	initiated and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5622969	29018469	YZ	2	initiated and designed the research|collected the materials and performed the experiments|wrote and revised the paper	collected the materials and performed the experiments	Performed the experiments	Investigation	YES
5622969	29018469	YZ	2	initiated and designed the research|collected the materials and performed the experiments|wrote and revised the paper	wrote and revised the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3520775	23072492	CK	2	performed the 2t4k modeling of the preclinical data and contributed to the interpretation of data	performed the 2t4k modeling of the preclinical data and contributed to the interpretation of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Methodology|Resources	YES
3520775	23072492	JM	2	is the main author of the manuscript and performed all nlme modeling	is the main author of the manuscript and performed all nlme modeling	Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
3520775	23072492	JPB	2	contributed to the conception and design of the study, and acquired the preclinical data	contributed to the conception and design of the study, and acquired the preclinical data	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceptualization|Investigation|Methodology|Resources	YES
3520775	23072492	MB	2	performed the human study including data acquisition and modeling	performed the human study including data acquisition and modeling	Performed the experiments	Investigation|Methodology	YES
3520775	23072492	MM	2	contributed to the interpretation of data and drafting of the manuscript	contributed to the interpretation of data and drafting of the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
3520775	23072492	OL	2	contributed to the conception and design of the study, and was also involved in drafting the manuscript	contributed to the conception and design of the study, and was also involved in drafting the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
3520775	23072492	RAV	2	contributed to the interpretation of data and drafting of the manuscript	contributed to the interpretation of data and drafting of the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
3520775	23072492	SS	2	contributed to the development of the nlme model and to the drafting of the manuscript	contributed to the development of the nlme model and to the drafting of the manuscript	Performed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4409205	25909781	ACBJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409205	25909781	ACBJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409205	25909781	ACBJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409205	25909781	MAK	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409205	25909781	MK	PLoS5	Reviewed the manuscripts and provided expert advice	Reviewed the manuscripts and provided expert advice	Wrote the paper	Writing - Review & Editing	YES
4409205	25909781	MMJ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409205	25909781	QZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409205	25909781	SS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409205	25909781	TGC	PLoS5	Reviewed the manuscripts and provided expert advice	Reviewed the manuscripts and provided expert advice	Wrote the paper	Writing - Review & Editing	YES
4409205	25909781	YH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409205	25909781	YH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409205	25909781	YH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409205	25909781	YH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5432975	28506205	LLM	2	is the senior coauthor|contributed to the study concept, interpretation, and writing of the manuscript	is the senior coauthor	-	-	NO
5432975	28506205	LLM	2	is the senior coauthor|contributed to the study concept, interpretation, and writing of the manuscript	contributed to the study concept, interpretation, and writing of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
5432975	28506205	LWML	2	is the first and corresponding author|has made contributions to the conception, data acquisition, analysis and interpretation of the results, and drafting of the manuscript	is the first and corresponding author	-	-	NO
5432975	28506205	LWML	2	is the first and corresponding author|has made contributions to the conception, data acquisition, analysis and interpretation of the results, and drafting of the manuscript	has made contributions to the conception, data acquisition, analysis and interpretation of the results, and drafting of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Resources|Writing - Original Draft	YES
5432975	28506205	ML	2	is a coauthor	is a coauthor	-	-	NO
5432975	28506205	QTL	2	tumor vs	tumor vs	-	-	NO
1762421	17205124	DT	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762421	17205124	DT	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762421	17205124	GC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762421	17205124	GC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762421	17205124	GC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762421	17205124	MP	PLoS5	Technical assistance with preparations of cells and apoptotic preys	Technical assistance with preparations of cells and apoptotic preys	Performed the experiments	Investigation	YES
1762421	17205124	VM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762421	17205124	VV	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1762421	17205124	YH	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762421	17205124	YH	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762421	17205124	ZM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1762421	17205124	ZZ	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762421	17205124	ZZ	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
3524758	23021206	HK	2	carried out all experiments and analyzed the data of in vitro binding assay and animal experiments	carried out all experiments and analyzed the data of in vitro binding assay and animal experiments	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3524758	23021206	IV-OH	2	in analyzing and interpreting the data	in analyzing and interpreting the data	Analyzed the data	Formal analysis	YES
3524758	23021206	KO	2	designed and took part in all aspects of this study and drafted the manuscript	designed and took part in all aspects of this study and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3524758	23021206	YK	2	contributed in the in vitro binding assay and metabolite analysis	contributed in the in vitro binding assay and metabolite analysis	Performed the experiments	Investigation	YES
5932637	29722482	BL	2	for design of neurodevelopmental sub-study|performed the neurodevelopmental assessments|wrote the first draft of the paper and all co-authors contributed to interpreting findings and writing the manuscript	for design of neurodevelopmental sub-study	Conceived and designed the experiments	Methodology	YES
5932637	29722482	BL	2	for design of neurodevelopmental sub-study|performed the neurodevelopmental assessments|wrote the first draft of the paper and all co-authors contributed to interpreting findings and writing the manuscript	performed the neurodevelopmental assessments	Performed the experiments	Investigation	YES
5932637	29722482	BL	2	for design of neurodevelopmental sub-study|performed the neurodevelopmental assessments|wrote the first draft of the paper and all co-authors contributed to interpreting findings and writing the manuscript	wrote the first draft of the paper and all co-authors contributed to interpreting findings and writing the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5932637	29722482	MC	2	wrote the first draft of the paper and all co-authors contributed to interpreting findings and writing the manuscript	wrote the first draft of the paper and all co-authors contributed to interpreting findings and writing the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5932637	29722482	MK	2	was the statistician for the neurodevelopmental sub-study	was the statistician for the neurodevelopmental sub-study	Analyzed the data	Formal analysis	YES
5932637	29722482	PES	2	performed the neurodevelopmental assessments	performed the neurodevelopmental assessments	Performed the experiments	Investigation	YES
5622977	29018456	AN	2	all contributed to the redaction of this review	all contributed to the redaction of this review	-	-	NO
5622977	29018456	CP	2	all contributed to the redaction of this review	all contributed to the redaction of this review	-	-	NO
5622977	29018456	ML	2	all contributed to the redaction of this review	all contributed to the redaction of this review	-	-	NO
5622977	29018456	VV	2	all contributed to the redaction of this review	all contributed to the redaction of this review	-	-	NO
4409206	25909589	AM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409206	25909589	AM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4409206	25909589	AM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409206	25909589	EH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409206	25909589	EH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409206	25909589	FH	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409206	25909589	FH	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409206	25909589	FH	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409206	25909589	FH	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409206	25909589	SKG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409206	25909589	SKG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409206	25909589	SL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409206	25909589	SL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5433024	28506212	AG	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5433024	28506212	HP	PLoS52	developed the software package	developed the software package	Contributed reagents/materials/analysis tools	Software	YES
5433024	28506212	LJZ	PLoS52	conceived and designed the computational method|developed the software package|analyzed the data|wrote the paper	conceived and designed the computational method	Conceived and designed the experiments|Performed the experiments	Conceptualization|Formal analysis|Methodology	YES
5433024	28506212	LJZ	PLoS52	conceived and designed the computational method|developed the software package|analyzed the data|wrote the paper	developed the software package	Contributed reagents/materials/analysis tools	Software	YES
5433024	28506212	LJZ	PLoS52	conceived and designed the computational method|developed the software package|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5433024	28506212	LJZ	PLoS52	conceived and designed the computational method|developed the software package|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5433024	28506212	ML	PLoS52	developed the software package	developed the software package	Contributed reagents/materials/analysis tools	Software	YES
5433024	28506212	SAW	PLoS52	conceived and designed the computational method|wrote the paper	conceived and designed the computational method	Conceived and designed the experiments|Performed the experiments	Conceptualization|Formal analysis|Methodology	YES
5433024	28506212	SAW	PLoS52	conceived and designed the computational method|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3531252	22776065	AT	2	carried out the design of this study and drafted the manuscript|participated in the pet studies|participated in the data analysis, data interpretation, and revising of the manuscript	carried out the design of this study and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
3531252	22776065	AT	2	carried out the design of this study and drafted the manuscript|participated in the pet studies|participated in the data analysis, data interpretation, and revising of the manuscript	participated in the pet studies	-	-	NO
3531252	22776065	AT	2	carried out the design of this study and drafted the manuscript|participated in the pet studies|participated in the data analysis, data interpretation, and revising of the manuscript	participated in the data analysis, data interpretation, and revising of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
3531252	22776065	BG	2	carried out the autoradiography studies|participated in the pet studies	carried out the autoradiography studies	Performed the experiments	Investigation	YES
3531252	22776065	BG	2	carried out the autoradiography studies|participated in the pet studies	participated in the pet studies	-	-	NO
3531252	22776065	CH	2	carried out the design of this study and drafted the manuscript|participated in the data analysis, data interpretation, and revising of the manuscript	carried out the design of this study and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
3531252	22776065	CH	2	carried out the design of this study and drafted the manuscript|participated in the data analysis, data interpretation, and revising of the manuscript	participated in the data analysis, data interpretation, and revising of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
3531252	22776065	JDA	2	participated in the pet studies	participated in the pet studies	-	-	NO
3531252	22776065	RN	2	carried out the metabolite analysis and measurement of protein binding	carried out the metabolite analysis and measurement of protein binding	Performed the experiments	Investigation	YES
3531252	22776065	SJF	2	participated in the pet studies	participated in the pet studies	-	-	NO
3531252	22776065	TF	2	carried out the design of this study and drafted the manuscript|carried out the autoradiography studies	carried out the design of this study and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
3531252	22776065	TF	2	carried out the design of this study and drafted the manuscript|carried out the autoradiography studies	carried out the autoradiography studies	Performed the experiments	Investigation	YES
1762422	17205140	AM	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762422	17205140	AM	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762422	17205140	DC	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762422	17205140	SL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762422	17205140	SL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762422	17205140	SL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762422	17205140	SL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762422	17205140	YZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762422	17205140	YZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762422	17205140	YZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762422	17205140	YZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762422	17205140	YZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5622981	29018461	CS	4	Design of experiment by|Experiments performed by|First draft done of the paper by	Design of experiment by	Conceived and designed the experiments	Methodology	YES
5622981	29018461	CS	4	Design of experiment by|Experiments performed by|First draft done of the paper by	Experiments performed by	Performed the experiments	Investigation	YES
5622981	29018461	CS	4	Design of experiment by|Experiments performed by|First draft done of the paper by	First draft done of the paper by	Wrote the paper	Writing - Original Draft	YES
5622981	29018461	FS	4	Design of experiment by|Suggestions of this paper made by	Design of experiment by	Conceived and designed the experiments	Methodology	YES
5622981	29018461	FS	4	Design of experiment by|Suggestions of this paper made by	Suggestions of this paper made by	-	-	NO
5622981	29018461	HC	4	Design of experiment by|Suggestions of this paper made by	Design of experiment by	Conceived and designed the experiments	Methodology	YES
5622981	29018461	HC	4	Design of experiment by|Suggestions of this paper made by	Suggestions of this paper made by	-	-	NO
5622981	29018461	JD	4	Design of experiment by	Design of experiment by	Conceived and designed the experiments	Methodology	YES
5622981	29018461	JZ	4	Design of experiment by	Design of experiment by	Conceived and designed the experiments	Methodology	YES
5622981	29018461	LG	4	Design of experiment by|Experiments performed by	Design of experiment by	Conceived and designed the experiments	Methodology	YES
5622981	29018461	LG	4	Design of experiment by|Experiments performed by	Experiments performed by	Performed the experiments	Investigation	YES
5622981	29018461	XT	4	Design of experiment by|Experiments performed by|First draft done of the paper by	Design of experiment by	Conceived and designed the experiments	Methodology	YES
5622981	29018461	XT	4	Design of experiment by|Experiments performed by|First draft done of the paper by	Experiments performed by	Performed the experiments	Investigation	YES
5622981	29018461	XT	4	Design of experiment by|Experiments performed by|First draft done of the paper by	First draft done of the paper by	Wrote the paper	Writing - Original Draft	YES
5622981	29018461	YS	4	Design of experiment by|Experiments performed by|Suggestions of this paper made by	Design of experiment by	Conceived and designed the experiments	Methodology	YES
5622981	29018461	YS	4	Design of experiment by|Experiments performed by|Suggestions of this paper made by	Experiments performed by	Performed the experiments	Investigation	YES
5622981	29018461	YS	4	Design of experiment by|Experiments performed by|Suggestions of this paper made by	Suggestions of this paper made by	-	-	NO
4409207	25909504	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409207	25909504	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409207	25909504	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409207	25909504	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409207	25909504	AS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409207	25909504	AS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409207	25909504	JR	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409207	25909504	JR	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409207	25909504	LL	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409207	25909504	LL	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409207	25909504	SH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409207	25909504	SH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409207	25909504	SH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409207	25909504	SH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3538506	22682112	DOTATOC	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3538506	22682112	HJW	2	gave advice in the interpretation of the data and critically reviewed the manuscript	gave advice in the interpretation of the data and critically reviewed the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
3538506	22682112	NODAGA-RGD	2	critically reviewed the manuscript	critically reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
1762423	17205123	AV	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762423	17205123	AV	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762423	17205123	DB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762423	17205123	DB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762423	17205123	DB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762423	17205123	DB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762423	17205123	FG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762423	17205123	FG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762423	17205123	FG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762423	17205123	FG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762423	17205123	FG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762423	17205123	SZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762423	17205123	SZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762423	17205123	SZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5622985	29018471	BM	2	conceived the topic	conceived the topic	Conceived and designed the experiments	Conceptualization	YES
5622985	29018471	C-CY	2	conceived the topic|wrote the manuscript	conceived the topic	Conceived and designed the experiments	Conceptualization	YES
5622985	29018471	C-CY	2	conceived the topic|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5622985	29018471	HZ	2	drew the picture of rice life cycle	drew the picture of rice life cycle	-	Visualization	YES
5622985	29018471	J-SZ	2	conceived the topic|revised the final version	conceived the topic	Conceived and designed the experiments	Conceptualization	YES
5622985	29018471	J-SZ	2	conceived the topic|revised the final version	revised the final version	Wrote the paper	Writing - Review & Editing	YES
5622985	29018471	S-YC	2	conceived the topic	conceived the topic	Conceived and designed the experiments	Conceptualization	YES
5433025	28506207	AWEF	7	conceived and designed the experimental study, performed data analysis, and wrote/edited the paper	conceived and designed the experimental study, performed data analysis, and wrote/edited the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5433025	28506207	SB	7	established the raw data format, conducted the initial data analysis, and performed statistical analysis on the data	established the raw data format, conducted the initial data analysis, and performed statistical analysis on the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5433025	28506207	SD	7	carried out experimental design, conducted the experimental work, conducted data analysis, prepared the figures, and wrote the paper	carried out experimental design, conducted the experimental work, conducted data analysis, prepared the figures, and wrote the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Visualization|Writing - Original Draft	YES
3544653	23168248	AAL	2	designed the study|supervised the data analyses	designed the study	Conceived and designed the experiments	Methodology	YES
3544653	23168248	AAL	2	designed the study|supervised the data analyses	supervised the data analyses	Analyzed the data	Formal analysis|Supervision	YES
3544653	23168248	All authors	2	edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
3544653	23168248	HNG	2	did all sample analyses	did all sample analyses	Analyzed the data	Formal analysis	YES
3544653	23168248	LWvG	2	recruited and scanned the subjects, performed the data analyses, and drafted the manuscript	recruited and scanned the subjects, performed the data analyses, and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3544653	23168248	MCH	2	did the data quality control and drafted the manuscript|supervised the data analyses	did the data quality control and drafted the manuscript	Performed the experiments|Wrote the paper	Data curation|Validation|Writing - Original Draft	YES
3544653	23168248	MCH	2	did the data quality control and drafted the manuscript|supervised the data analyses	supervised the data analyses	Analyzed the data	Formal analysis|Supervision	YES
3544653	23168248	MD	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
3544653	23168248	NJH	2	performed the data acquisition	performed the data acquisition	Performed the experiments	Investigation	YES
3544653	23168248	PS	2	inserted the arterial lines	inserted the arterial lines	-	-	NO
1762424	17205126	CS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762424	17205126	CS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1762424	17205126	CS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1762424	17205126	CS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762424	17205126	KJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762424	17205126	KJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762424	17205126	KJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762424	17205126	KV	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762424	17205126	KV	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762424	17205126	MD	PLoS5	Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1762424	17205126	MD	PLoS5	Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1762424	17205126	MD	PLoS5	Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1762424	17205126	MD	PLoS5	Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1762424	17205126	MD	PLoS5	Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762424	17205126	MD	PLoS5	Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762424	17205126	NL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1762424	17205126	NL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1762424	17205126	NL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762424	17205126	SP	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1762424	17205126	SP	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1762424	17205126	SP	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762424	17205126	TJ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1762424	17205126	TJ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1762424	17205126	TJ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762424	17205126	TM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762424	17205126	TM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1762424	17205126	TM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1762424	17205126	TM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5978638	29633552	Alessio Aghemo	2	designed the review, drafted the manuscript and critically revised it	designed the review, drafted the manuscript and critically revised it	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5978638	29633552	Lionel Piroth	2	designed the review, drafted the manuscript and critically revised it	designed the review, drafted the manuscript and critically revised it	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5978638	29633552	Sanjay Bhagani	2	designed the review, drafted the manuscript and critically revised it	designed the review, drafted the manuscript and critically revised it	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4409208	25910193	GR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409208	25910193	GR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409208	25910193	GR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409208	25910193	GR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409208	25910193	MA	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409208	25910193	NL	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409208	25910193	NL	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409208	25910193	RG	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409208	25910193	RG	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409208	25910193	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409208	25910193	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409208	25910193	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409208	25910193	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409208	25910193	WPQ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409208	25910193	WPQ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409208	25910193	WPQ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409208	25910193	WPQ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5622987	29018467	DL	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5622987	29018467	DS	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5622987	29018467	HR	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5622987	29018467	JC	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5622987	29018467	NH	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5622987	29018467	WH	PLoS52	designed the experiments|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5622987	29018467	WH	PLoS52	designed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5622987	29018467	YL	PLoS52	designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5622987	29018467	YL	PLoS52	designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5622987	29018467	YL	PLoS52	designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5622987	29018467	YL	PLoS52	designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5622987	29018467	ZL	PLoS52	designed the experiments|revised the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5622987	29018467	ZL	PLoS52	designed the experiments|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5622987	29018467	ZX	PLoS52	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
3557172	23281702	AA	2	reviewed current literature and wrote the manuscript	reviewed current literature and wrote the manuscript	Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
3557172	23281702	AR	2	provided valuable intellectual advice on the imaging studies|critically reviewed the manuscript	provided valuable intellectual advice on the imaging studies	Analyzed the data	Visualization	YES
3557172	23281702	AR	2	provided valuable intellectual advice on the imaging studies|critically reviewed the manuscript	critically reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
3557172	23281702	SJ	2	provided valuable input to the biology of the target molecule vap-1|critically reviewed the manuscript	provided valuable input to the biology of the target molecule vap-1	-	-	NO
3557172	23281702	SJ	2	provided valuable input to the biology of the target molecule vap-1|critically reviewed the manuscript	critically reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
1762425	17205109	ES	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1762425	17205109	JB	PLoS5	Conceived and designed the experiments|Analyzed the data|Revised the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762425	17205109	JB	PLoS5	Conceived and designed the experiments|Analyzed the data|Revised the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762425	17205109	JB	PLoS5	Conceived and designed the experiments|Analyzed the data|Revised the paper	Revised the paper	Wrote the paper	Writing - Review & Editing	YES
1762425	17205109	PR	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the methods for growth chambers	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762425	17205109	PR	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the methods for growth chambers	Performed the experiments	Performed the experiments	Investigation	YES
1762425	17205109	PR	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the methods for growth chambers	Wrote the methods for growth chambers	Performed the experiments|Wrote the paper	Writing - Original Draft	YES
1762425	17205109	YL	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762425	17205109	YL	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5978639	29633580	All authors	2	contributed equally to drafting the content, editing and reviewing the manuscript	contributed equally to drafting the content, editing and reviewing the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5433093	28506253	BZ	PLoS52	conceived of and designed the experiments|performed the experiments and data analysis|wrote the manuscript	conceived of and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5433093	28506253	BZ	PLoS52	conceived of and designed the experiments|performed the experiments and data analysis|wrote the manuscript	performed the experiments and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5433093	28506253	BZ	PLoS52	conceived of and designed the experiments|performed the experiments and data analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5433093	28506253	HYS	PLoS52	conducted the qpcr validation	conducted the qpcr validation	Performed the experiments	Investigation|Validation	YES
5433093	28506253	MYX	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5433093	28506253	PL	PLoS52	conceived of and designed the experiments|contributed reagents/materials and provided the experimental environment|wrote the manuscript	conceived of and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5433093	28506253	PL	PLoS52	conceived of and designed the experiments|contributed reagents/materials and provided the experimental environment|wrote the manuscript	contributed reagents/materials and provided the experimental environment	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5433093	28506253	PL	PLoS52	conceived of and designed the experiments|contributed reagents/materials and provided the experimental environment|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5433093	28506253	XWG	PLoS52	contributed reagents/materials and provided the experimental environment	contributed reagents/materials and provided the experimental environment	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4409209	25910222	AA	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409209	25910222	AA	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409209	25910222	AD	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409209	25910222	LV	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409209	25910222	LV	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409209	25910222	LV	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409209	25910222	LV	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409209	25910222	MCVG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409209	25910222	MCVG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409209	25910222	MCVG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409209	25910222	MCVG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409209	25910222	MGHB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409209	25910222	MGHB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409209	25910222	MGHB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409209	25910222	MGHB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409209	25910222	MRK	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409209	25910222	RZ	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409209	25910222	SMH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409209	25910222	SMH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409209	25910222	SMH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409209	25910222	SMH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409209	25910222	WB	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4538407	26339625	All the authors	2	equally contributed to the review	equally contributed to the review	-	-	NO
3557183	23343347	CT	2	measurements, image reconstructions, image fusion, and image analysis, and drafted the manuscript|measurements, carried out interpretation of data, and drafted the manuscript|measurements and participated in image reconstructions|measurements, image reconstructions, and interpretation of data, and drafted the manuscript	measurements, image reconstructions, image fusion, and image analysis, and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Investigation|Visualization|Writing - Original Draft	YES
3557183	23343347	CT	2	measurements, image reconstructions, image fusion, and image analysis, and drafted the manuscript|measurements, carried out interpretation of data, and drafted the manuscript|measurements and participated in image reconstructions|measurements, image reconstructions, and interpretation of data, and drafted the manuscript	measurements, carried out interpretation of data, and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3557183	23343347	CT	2	measurements, image reconstructions, image fusion, and image analysis, and drafted the manuscript|measurements, carried out interpretation of data, and drafted the manuscript|measurements and participated in image reconstructions|measurements, image reconstructions, and interpretation of data, and drafted the manuscript	measurements and participated in image reconstructions	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
3557183	23343347	CT	2	measurements, image reconstructions, image fusion, and image analysis, and drafted the manuscript|measurements, carried out interpretation of data, and drafted the manuscript|measurements and participated in image reconstructions|measurements, image reconstructions, and interpretation of data, and drafted the manuscript	measurements, image reconstructions, and interpretation of data, and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Visualization|Writing - Original Draft	YES
3557183	23343347	MEN	2	carried out image reconstructions and image fusion and drafted the manuscript	carried out image reconstructions and image fusion and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Investigation|Visualization|Writing - Original Draft	YES
5622988	29018468	CS	2	wrote the manuscript and gave final approval for publication	wrote the manuscript and gave final approval for publication	Wrote the paper	Writing - Original Draft	YES
5622988	29018468	XY	2	collected data|wrote the manuscript and gave final approval for publication	collected data	Performed the experiments	Investigation	YES
5622988	29018468	XY	2	collected data|wrote the manuscript and gave final approval for publication	wrote the manuscript and gave final approval for publication	Wrote the paper	Writing - Original Draft	YES
5622988	29018468	YG	2	designed the research|analyzed data|wrote the manuscript and gave final approval for publication	designed the research	Conceived and designed the experiments	Methodology	YES
5622988	29018468	YG	2	designed the research|analyzed data|wrote the manuscript and gave final approval for publication	analyzed data	Analyzed the data	Formal analysis	YES
5622988	29018468	YG	2	designed the research|analyzed data|wrote the manuscript and gave final approval for publication	wrote the manuscript and gave final approval for publication	Wrote the paper	Writing - Original Draft	YES
5622988	29018468	YJ	2	wrote the manuscript and gave final approval for publication	wrote the manuscript and gave final approval for publication	Wrote the paper	Writing - Original Draft	YES
5622988	29018468	ZT	2	designed the research|collected data|wrote the manuscript and gave final approval for publication	designed the research	Conceived and designed the experiments	Methodology	YES
5622988	29018468	ZT	2	designed the research|collected data|wrote the manuscript and gave final approval for publication	collected data	Performed the experiments	Investigation	YES
5622988	29018468	ZT	2	designed the research|collected data|wrote the manuscript and gave final approval for publication	wrote the manuscript and gave final approval for publication	Wrote the paper	Writing - Original Draft	YES
3590011	23482508	All	2	listed authors were responsible for data interpretation and conclusions	listed authors were responsible for data interpretation and conclusions	Analyzed the data	Formal analysis	YES
3590011	23482508	Dr Bunker	2	compiled the raw data, and the demographics and patient disposition data	compiled the raw data, and the demographics and patient disposition data	-	Data curation	YES
3590011	23482508	Dr Olin	2	compiled the raw data, and the demographics and patient disposition data	compiled the raw data, and the demographics and patient disposition data	-	Data curation	YES
3590011	23482508	Mr Jayewardene	2	compiled the raw data, and the demographics and patient disposition data	compiled the raw data, and the demographics and patient disposition data	-	Data curation	YES
1762426	17205111	AO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762426	17205111	AO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1762426	17205111	AO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1762426	17205111	AO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762426	17205111	GS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762426	17205111	GS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1762426	17205111	GS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1762426	17205111	GS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762426	17205111	JC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762426	17205111	JC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762426	17205111	JC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762426	17205111	MM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762426	17205111	MM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1762426	17205111	MM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1762426	17205111	MM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5978641	29485764	All authors	2	wrote, edited and approved the final manuscript	wrote, edited and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5978641	29485764	BV	2	conducted primary research and analysis	conducted primary research and analysis	Performed the experiments	Investigation	YES
5978641	29485764	ET	2	conducted primary research and analysis	conducted primary research and analysis	Performed the experiments	Investigation	YES
5978641	29485764	JD	2	conducted primary research and analysis	conducted primary research and analysis	Performed the experiments	Investigation	YES
5978641	29485764	LC	2	conducted primary research and analysis	conducted primary research and analysis	Performed the experiments	Investigation	YES
5978641	29485764	NZ	2	guided methods and analysis	guided methods and analysis	Performed the experiments	Supervision	YES
5978641	29485764	RH	2	conducted primary research and analysis	conducted primary research and analysis	Performed the experiments	Investigation	YES
4409210	25909190	DNS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409210	25909190	DNS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409210	25909190	DNS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409210	25909190	DNS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409210	25909190	FL	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409210	25909190	FL	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409210	25909190	FL	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409210	25909190	JDT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409210	25909190	JDT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409210	25909190	JDT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409210	25909190	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409210	25909190	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409210	25909190	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409210	25909190	PH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409210	25909190	PH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409210	25909190	PH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409210	25909190	QC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409210	25909190	QC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409210	25909190	SCJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409210	25909190	SCJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409210	25909190	SCJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409210	25909190	SCJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3558387	23289862	CC	2	conceived the study design and drafted the manuscript	conceived the study design and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
3558387	23289862	FA	2	performed most of the pet examinations, the visual analysis, the spm analysis, coordinated the results and contributed to draft the manuscript	performed most of the pet examinations, the visual analysis, the spm analysis, coordinated the results and contributed to draft the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Project administration|Visualization|Writing - Original Draft	YES
3558387	23289862	FC	2	performed pet visual analysis and reviewed the manuscript	performed pet visual analysis and reviewed the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Investigation|Visualization|Writing - Review & Editing	YES
3558387	23289862	LHP	2	read mri examinations	read mri examinations	Performed the experiments	Investigation	YES
3558387	23289862	OD	2	followed and referred the patients and extensively reviewed the manuscript	followed and referred the patients and extensively reviewed the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
3558387	23289862	PCR	2	performed the statistical analyses	performed the statistical analyses	Analyzed the data	Formal analysis	YES
3558387	23289862	SR	2	participated in the design of the study	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
3558387	23289862	VB	2	performed some pet examinations, participated in its design and helped to draft the manuscript	performed some pet examinations, participated in its design and helped to draft the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5623100	29018459	AHi	2	conducted picoplex single-cell sequencing, contributed to the manuscript and edited the manuscript	conducted picoplex single-cell sequencing, contributed to the manuscript and edited the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5623100	29018459	AHo	2	conceptualized the experiments, supervised the analyses, contributed to the manuscript and edited the manuscript	conceptualized the experiments, supervised the analyses, contributed to the manuscript and edited the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Supervision|Writing - Review & Editing	YES
5623100	29018459	All authors	2	read and approved the final version of this manuscript	read and approved the final version of this manuscript	-	-	NO
5623100	29018459	JF	2	conducted flow-sorting, contributed to the manuscript and edited the manuscript	conducted flow-sorting, contributed to the manuscript and edited the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5623100	29018459	MM	2	processed all raw data, analyzed the data, contributed to the manuscript and edited the manuscript	processed all raw data, analyzed the data, contributed to the manuscript and edited the manuscript	Analyzed the data|Wrote the paper	Data curation|Formal analysis|Writing - Review & Editing	YES
5623100	29018459	SD	2	isolated pollen nuclei, conducted flow-sorting, analyzed the data, and wrote the manuscript	isolated pollen nuclei, conducted flow-sorting, analyzed the data, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
543457	15610564	AMK	2	performed bioinformatics and statistical analysis|programmed the fountain software package to include the sage analysis modules|helped draft the manuscript	performed bioinformatics and statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
543457	15610564	AMK	2	performed bioinformatics and statistical analysis|programmed the fountain software package to include the sage analysis modules|helped draft the manuscript	programmed the fountain software package to include the sage analysis modules	Contributed reagents/materials/analysis tools	Software	YES
543457	15610564	AMK	2	performed bioinformatics and statistical analysis|programmed the fountain software package to include the sage analysis modules|helped draft the manuscript	helped draft the manuscript	Wrote the paper	Writing - Original Draft	YES
543457	15610564	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
543457	15610564	CJ	2	performed clone management, sequencing and data analysis	performed clone management, sequencing and data analysis	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
543457	15610564	EE	2	performed bioinformatics and statistical analysis	performed bioinformatics and statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
543457	15610564	HA	2	participated in the design of the study and its coordination|performed confirmation pcr analysis|helped draft the manuscript	participated in the design of the study and its coordination	Conceived and designed the experiments	Methodology|Project administration	YES
543457	15610564	HA	2	participated in the design of the study and its coordination|performed confirmation pcr analysis|helped draft the manuscript	performed confirmation pcr analysis	Performed the experiments	Investigation	YES
543457	15610564	HA	2	participated in the design of the study and its coordination|performed confirmation pcr analysis|helped draft the manuscript	helped draft the manuscript	Wrote the paper	Writing - Original Draft	YES
543457	15610564	JMB	2	conceived the project|participated in the design of the study and its coordination|performed bioinformatics and statistical analysis|programmed the fountain software package to include the sage analysis modules|helped draft the manuscript	conceived the project	Conceived and designed the experiments	Conceptualization	YES
543457	15610564	JMB	2	conceived the project|participated in the design of the study and its coordination|performed bioinformatics and statistical analysis|programmed the fountain software package to include the sage analysis modules|helped draft the manuscript	participated in the design of the study and its coordination	Conceived and designed the experiments	Methodology|Project administration	YES
543457	15610564	JMB	2	conceived the project|participated in the design of the study and its coordination|performed bioinformatics and statistical analysis|programmed the fountain software package to include the sage analysis modules|helped draft the manuscript	performed bioinformatics and statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
543457	15610564	JMB	2	conceived the project|participated in the design of the study and its coordination|performed bioinformatics and statistical analysis|programmed the fountain software package to include the sage analysis modules|helped draft the manuscript	programmed the fountain software package to include the sage analysis modules	Contributed reagents/materials/analysis tools	Software	YES
543457	15610564	JMB	2	conceived the project|participated in the design of the study and its coordination|performed bioinformatics and statistical analysis|programmed the fountain software package to include the sage analysis modules|helped draft the manuscript	helped draft the manuscript	Wrote the paper	Writing - Original Draft	YES
543457	15610564	MBW	2	conceived the project|participated in the design of the study and its coordination|constructed the libraries|performed clone management, sequencing and data analysis|performed bioinformatics and statistical analysis|helped draft the manuscript	conceived the project	Conceived and designed the experiments	Conceptualization	YES
543457	15610564	MBW	2	conceived the project|participated in the design of the study and its coordination|constructed the libraries|performed clone management, sequencing and data analysis|performed bioinformatics and statistical analysis|helped draft the manuscript	participated in the design of the study and its coordination	Conceived and designed the experiments	Methodology|Project administration	YES
543457	15610564	MBW	2	conceived the project|participated in the design of the study and its coordination|constructed the libraries|performed clone management, sequencing and data analysis|performed bioinformatics and statistical analysis|helped draft the manuscript	constructed the libraries	Performed the experiments	Investigation	YES
543457	15610564	MBW	2	conceived the project|participated in the design of the study and its coordination|constructed the libraries|performed clone management, sequencing and data analysis|performed bioinformatics and statistical analysis|helped draft the manuscript	performed clone management, sequencing and data analysis	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
543457	15610564	MBW	2	conceived the project|participated in the design of the study and its coordination|constructed the libraries|performed clone management, sequencing and data analysis|performed bioinformatics and statistical analysis|helped draft the manuscript	performed bioinformatics and statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
543457	15610564	MBW	2	conceived the project|participated in the design of the study and its coordination|constructed the libraries|performed clone management, sequencing and data analysis|performed bioinformatics and statistical analysis|helped draft the manuscript	helped draft the manuscript	Wrote the paper	Writing - Original Draft	YES
543457	15610564	MC	2	performed clone management, sequencing and data analysis	performed clone management, sequencing and data analysis	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
543457	15610564	MS	2	performed clone management, sequencing and data analysis	performed clone management, sequencing and data analysis	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
543457	15610564	NH	2	performed clone management, sequencing and data analysis	performed clone management, sequencing and data analysis	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
543457	15610564	RBC	2	participated in the design of the study and its coordination|performed clone management, sequencing and data analysis|performed bioinformatics and statistical analysis|helped draft the manuscript	participated in the design of the study and its coordination	Conceived and designed the experiments	Methodology|Project administration	YES
543457	15610564	RBC	2	participated in the design of the study and its coordination|performed clone management, sequencing and data analysis|performed bioinformatics and statistical analysis|helped draft the manuscript	performed clone management, sequencing and data analysis	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
543457	15610564	RBC	2	participated in the design of the study and its coordination|performed clone management, sequencing and data analysis|performed bioinformatics and statistical analysis|helped draft the manuscript	performed bioinformatics and statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
543457	15610564	RBC	2	participated in the design of the study and its coordination|performed clone management, sequencing and data analysis|performed bioinformatics and statistical analysis|helped draft the manuscript	helped draft the manuscript	Wrote the paper	Writing - Original Draft	YES
543457	15610564	SAGE	2	tag production and reference gene assignment	tag production and reference gene assignment	-	-	NO
543457	15610564	VL	2	performed bioinformatics and statistical analysis|helped draft the manuscript	performed bioinformatics and statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
543457	15610564	VL	2	performed bioinformatics and statistical analysis|helped draft the manuscript	helped draft the manuscript	Wrote the paper	Writing - Original Draft	YES
543457	15610564	YDW	2	performed clone management, sequencing and data analysis	performed clone management, sequencing and data analysis	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
3560220	22953701	CM	2	interpreted and analyzed the data, and wrote the paper|performed in vivo studies using the mouse subcutaneous xenograft model	interpreted and analyzed the data, and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3560220	22953701	CM	2	interpreted and analyzed the data, and wrote the paper|performed in vivo studies using the mouse subcutaneous xenograft model	performed in vivo studies using the mouse subcutaneous xenograft model	Performed the experiments	Investigation|Methodology	YES
3560220	22953701	HH	2	interpreted and analyzed the data, and wrote the paper|participated in the molecular genetic studies	interpreted and analyzed the data, and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3560220	22953701	HH	2	interpreted and analyzed the data, and wrote the paper|participated in the molecular genetic studies	participated in the molecular genetic studies	Performed the experiments	Investigation	YES
3560220	22953701	TS	2	generally supervised the study	generally supervised the study	-	Supervision	YES
3560220	22953701	YK	2	acquired the funds and gave critical advises	acquired the funds and gave critical advises	-	Funding acquisition	YES
3560220	22953701	YNJ	2	interpreted and analyzed the data, and wrote the paper	interpreted and analyzed the data, and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
1762427	17205142	HK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762427	17205142	HK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762427	17205142	HK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762427	17205142	HK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762427	17205142	JL	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762427	17205142	JL	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762427	17205142	KM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1762427	17205142	KO	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1762427	17205142	KR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762427	17205142	KR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762427	17205142	KR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4538410	26339617	Maria Tolia	2	contributed equally to this work	contributed equally to this work	-	-	NO
4538410	26339617	Nikolaos Tsoukalas	2	contributed equally to this work	contributed equally to this work	-	-	NO
5978642	29485749	COR	2	contributed to the concept, research, writing and revision, and coordination of authors	contributed to the concept, research, writing and revision, and coordination of authors	Conceived and designed the experiments|Wrote the paper	Conceptualization|Project administration|Writing - Review & Editing	YES
5978642	29485749	DTH	2	contributed to the concept, technical input and revision of drafts	contributed to the concept, technical input and revision of drafts	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
5978642	29485749	HG	2	contributed to the concept, research, writing and revision	contributed to the concept, research, writing and revision	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5978642	29485749	LH	2	contributed to the concept, technical input and revision of drafts	contributed to the concept, technical input and revision of drafts	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
5436443	28521739	BO	2	designed the experiment|analyzed data and wrote the manuscript	designed the experiment	Conceived and designed the experiments	Methodology	YES
5436443	28521739	BO	2	designed the experiment|analyzed data and wrote the manuscript	analyzed data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5436443	28521739	DP	2	designed the experiment	designed the experiment	Conceived and designed the experiments	Methodology	YES
5436443	28521739	HY	2	performed the genomics|analyzed data and wrote the manuscript	performed the genomics	Performed the experiments	Investigation	YES
5436443	28521739	HY	2	performed the genomics|analyzed data and wrote the manuscript	analyzed data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4409212	25910265	CM	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4409212	25910265	CM	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409212	25910265	IDL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409212	25910265	IDL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409212	25910265	IDL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409212	25910265	JG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409212	25910265	JG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409212	25910265	JG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409212	25910265	MCR	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409212	25910265	MCR	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409212	25910265	MGL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409212	25910265	MGL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409212	25910265	MGL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409212	25910265	MGL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409212	25910265	NRH	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4409212	25910265	NRH	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409212	25910265	RGD	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409212	25910265	RGD	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409212	25910265	RZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409212	25910265	RZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409212	25910265	RZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409212	25910265	RZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3561128	23316861	AMV	2	were responsible for the design and critical revision of the manuscript	were responsible for the design and critical revision of the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Review & Editing	YES
3561128	23316861	GMB	2	were responsible for the design and critical revision of the manuscript	were responsible for the design and critical revision of the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Review & Editing	YES
3561128	23316861	JN	2	were responsible for the design and critical revision of the manuscript	were responsible for the design and critical revision of the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Review & Editing	YES
3561128	23316861	OG	2	designed the study, carried out the pet imaging studies, analyzed the data, and wrote the manuscript	designed the study, carried out the pet imaging studies, analyzed the data, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Visualization|Writing - Original Draft	YES
3561128	23316861	PC	2	carried out and analyzed the pig mri studies	carried out and analyzed the pig mri studies	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3561128	23316861	SJ	2	were responsible for the design and critical revision of the manuscript	were responsible for the design and critical revision of the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Review & Editing	YES
3561128	23316861	VA	2	co-wrote the work	co-wrote the work	Wrote the paper	Writing - Original Draft	YES
1762428	17205128	AM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762428	17205128	DO	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762428	17205128	EG	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762428	17205128	EG	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762428	17205128	ER	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762428	17205128	GB	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762428	17205128	GB	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762428	17205128	IR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762428	17205128	IR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762428	17205128	IR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762428	17205128	IR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762428	17205128	LB	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1762428	17205128	LB	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762428	17205128	LC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762428	17205128	MG	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762428	17205128	MG	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762428	17205128	RF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762428	17205128	RF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762428	17205128	RF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762428	17205128	RM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762428	17205128	SC	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5623121	29018466	CA	2	designed the experimental setup|performed the analytical chemistry work, the gc-ms data extraction, metabolite identification|involved in the manuscript refinement	designed the experimental setup	Conceived and designed the experiments	Methodology	YES
5623121	29018466	CA	2	designed the experimental setup|performed the analytical chemistry work, the gc-ms data extraction, metabolite identification|involved in the manuscript refinement	performed the analytical chemistry work, the gc-ms data extraction, metabolite identification	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5623121	29018466	CA	2	designed the experimental setup|performed the analytical chemistry work, the gc-ms data extraction, metabolite identification|involved in the manuscript refinement	involved in the manuscript refinement	-	-	NO
5623121	29018466	CG	2	performed the analytical chemistry work, the gc-ms data extraction, metabolite identification|involved in the manuscript refinement	performed the analytical chemistry work, the gc-ms data extraction, metabolite identification	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5623121	29018466	CG	2	performed the analytical chemistry work, the gc-ms data extraction, metabolite identification|involved in the manuscript refinement	involved in the manuscript refinement	-	-	NO
5623121	29018466	EC	2	performed the sampling|performed the analytical chemistry work, the gc-ms data extraction, metabolite identification|wrote the article|involved in the manuscript refinement	performed the sampling	Performed the experiments	Investigation	YES
5623121	29018466	EC	2	performed the sampling|performed the analytical chemistry work, the gc-ms data extraction, metabolite identification|wrote the article|involved in the manuscript refinement	performed the analytical chemistry work, the gc-ms data extraction, metabolite identification	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5623121	29018466	EC	2	performed the sampling|performed the analytical chemistry work, the gc-ms data extraction, metabolite identification|wrote the article|involved in the manuscript refinement	wrote the article	Wrote the paper	Writing - Original Draft	YES
5623121	29018466	EC	2	performed the sampling|performed the analytical chemistry work, the gc-ms data extraction, metabolite identification|wrote the article|involved in the manuscript refinement	involved in the manuscript refinement	-	-	NO
5623121	29018466	GG	2	designed the experimental setup|performed the sampling|performed the statistical analysis|wrote the article|involved in the manuscript refinement	designed the experimental setup	Conceived and designed the experiments	Methodology	YES
5623121	29018466	GG	2	designed the experimental setup|performed the sampling|performed the statistical analysis|wrote the article|involved in the manuscript refinement	performed the sampling	Performed the experiments	Investigation	YES
5623121	29018466	GG	2	designed the experimental setup|performed the sampling|performed the statistical analysis|wrote the article|involved in the manuscript refinement	performed the statistical analysis	Analyzed the data	Formal analysis	YES
5623121	29018466	GG	2	designed the experimental setup|performed the sampling|performed the statistical analysis|wrote the article|involved in the manuscript refinement	wrote the article	Wrote the paper	Writing - Original Draft	YES
5623121	29018466	GG	2	designed the experimental setup|performed the sampling|performed the statistical analysis|wrote the article|involved in the manuscript refinement	involved in the manuscript refinement	-	-	NO
5623121	29018466	JH	2	designed the experimental setup|involved in the manuscript refinement	designed the experimental setup	Conceived and designed the experiments	Methodology	YES
5623121	29018466	JH	2	designed the experimental setup|involved in the manuscript refinement	involved in the manuscript refinement	-	-	NO
5623121	29018466	SL	2	designed the experimental setup|performed the sampling|performed the analytical chemistry work, the gc-ms data extraction, metabolite identification|performed the statistical analysis|wrote the article|involved in the manuscript refinement	designed the experimental setup	Conceived and designed the experiments	Methodology	YES
5623121	29018466	SL	2	designed the experimental setup|performed the sampling|performed the analytical chemistry work, the gc-ms data extraction, metabolite identification|performed the statistical analysis|wrote the article|involved in the manuscript refinement	performed the sampling	Performed the experiments	Investigation	YES
5623121	29018466	SL	2	designed the experimental setup|performed the sampling|performed the analytical chemistry work, the gc-ms data extraction, metabolite identification|performed the statistical analysis|wrote the article|involved in the manuscript refinement	performed the analytical chemistry work, the gc-ms data extraction, metabolite identification	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5623121	29018466	SL	2	designed the experimental setup|performed the sampling|performed the analytical chemistry work, the gc-ms data extraction, metabolite identification|performed the statistical analysis|wrote the article|involved in the manuscript refinement	performed the statistical analysis	Analyzed the data	Formal analysis	YES
5623121	29018466	SL	2	designed the experimental setup|performed the sampling|performed the analytical chemistry work, the gc-ms data extraction, metabolite identification|performed the statistical analysis|wrote the article|involved in the manuscript refinement	wrote the article	Wrote the paper	Writing - Original Draft	YES
5623121	29018466	SL	2	designed the experimental setup|performed the sampling|performed the analytical chemistry work, the gc-ms data extraction, metabolite identification|performed the statistical analysis|wrote the article|involved in the manuscript refinement	involved in the manuscript refinement	-	-	NO
3563455	23327687	CL	2	carried out all measurements and data processing and helped draft the manuscript	carried out all measurements and data processing and helped draft the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Investigation|Writing - Original Draft	YES
3563455	23327687	EQ	2	participated in data analysis and helped draft the manuscript	participated in data analysis and helped draft the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3563455	23327687	MB	2	participated in the study coordination and in the measurements	participated in the study coordination and in the measurements	Performed the experiments	Investigation|Project administration	YES
3563455	23327687	MHL	2	participated in the study coordination and in the measurements	participated in the study coordination and in the measurements	Performed the experiments	Investigation|Project administration	YES
3563455	23327687	NA	2	conceived the study, participated in its design and coordination and in the measurements, and drafted the manuscript	conceived the study, participated in its design and coordination and in the measurements, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Project administration|Writing - Original Draft	YES
3563455	23327687	ZG	2	participated in phantom data analysis and helped draft the manuscript	participated in phantom data analysis and helped draft the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4409214	25909997	HS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409214	25909997	HS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409214	25909997	HS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409214	25909997	HS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409214	25909997	JK	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4409214	25909997	JK	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4409214	25909997	JK	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409214	25909997	KK	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409214	25909997	MH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409214	25909997	MO	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4409214	25909997	MO	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409214	25909997	NH	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4409214	25909997	NH	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409214	25909997	SHY	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4409214	25909997	SHY	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409214	25909997	ST	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409214	25909997	ST	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409214	25909997	ST	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409214	25909997	TP	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5436446	28514956	CYT	7	Collection and/or assembly of data	Collection and/or assembly of data	Performed the experiments	Investigation	YES
5436446	28514956	LS	7	Conception and design, data analysis, financial support, manuscript writing	Conception and design, data analysis, financial support, manuscript writing	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Funding acquisition|Writing - Original Draft	YES
5436446	28514956	PS	7	Conception and design, collection and/or assembly of data, data analysis and interpretation, manuscript writing	Conception and design, collection and/or assembly of data, data analysis and interpretation, manuscript writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
1762429	17205114	JN	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762429	17205114	JN	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762429	17205114	JN	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762429	17205114	KA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762429	17205114	KA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762429	17205114	KA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762429	17205114	KA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3732634	23970831	Benpeng Li	2	contributed equally to this work and are joint first authors	contributed equally to this work and are joint first authors	-	-	NO
3732634	23970831	Qing Huang	2	contributed equally to this work and are joint first authors	contributed equally to this work and are joint first authors	-	-	NO
3570346	23136853	AK	2	conceived and designed the study|validated and synthesised the tracer|acquired the data|analysed and interpreted the data|critically edited and revised the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3570346	23136853	AK	2	conceived and designed the study|validated and synthesised the tracer|acquired the data|analysed and interpreted the data|critically edited and revised the manuscript	validated and synthesised the tracer	Performed the experiments	Validation	YES
3570346	23136853	AK	2	conceived and designed the study|validated and synthesised the tracer|acquired the data|analysed and interpreted the data|critically edited and revised the manuscript	acquired the data	Performed the experiments	Investigation	YES
3570346	23136853	AK	2	conceived and designed the study|validated and synthesised the tracer|acquired the data|analysed and interpreted the data|critically edited and revised the manuscript	analysed and interpreted the data	Analyzed the data	Formal analysis	YES
3570346	23136853	AK	2	conceived and designed the study|validated and synthesised the tracer|acquired the data|analysed and interpreted the data|critically edited and revised the manuscript	critically edited and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
3570346	23136853	CL	2	conceived and designed the study|analysed and interpreted the data|critically edited and revised the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3570346	23136853	CL	2	conceived and designed the study|analysed and interpreted the data|critically edited and revised the manuscript	analysed and interpreted the data	Analyzed the data	Formal analysis	YES
3570346	23136853	CL	2	conceived and designed the study|analysed and interpreted the data|critically edited and revised the manuscript	critically edited and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
3570346	23136853	FM	2	conceived and designed the study|acquired the data|analysed and interpreted the data|critically edited and revised the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3570346	23136853	FM	2	conceived and designed the study|acquired the data|analysed and interpreted the data|critically edited and revised the manuscript	acquired the data	Performed the experiments	Investigation	YES
3570346	23136853	FM	2	conceived and designed the study|acquired the data|analysed and interpreted the data|critically edited and revised the manuscript	analysed and interpreted the data	Analyzed the data	Formal analysis	YES
3570346	23136853	FM	2	conceived and designed the study|acquired the data|analysed and interpreted the data|critically edited and revised the manuscript	critically edited and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
3570346	23136853	GLR	2	acquired the data|quantified the data|critically edited and revised the manuscript	acquired the data	Performed the experiments	Investigation	YES
3570346	23136853	GLR	2	acquired the data|quantified the data|critically edited and revised the manuscript	quantified the data	-	-	NO
3570346	23136853	GLR	2	acquired the data|quantified the data|critically edited and revised the manuscript	critically edited and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
3570346	23136853	HA	2	quantified the data|analysed and interpreted the data	quantified the data	-	-	NO
3570346	23136853	HA	2	quantified the data|analysed and interpreted the data	analysed and interpreted the data	Analyzed the data	Formal analysis	YES
3570346	23136853	MCG	2	conceived and designed the study|acquired the data|quantified the data|analysed and interpreted the data|critically edited and revised the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3570346	23136853	MCG	2	conceived and designed the study|acquired the data|quantified the data|analysed and interpreted the data|critically edited and revised the manuscript	acquired the data	Performed the experiments	Investigation	YES
3570346	23136853	MCG	2	conceived and designed the study|acquired the data|quantified the data|analysed and interpreted the data|critically edited and revised the manuscript	quantified the data	-	-	NO
3570346	23136853	MCG	2	conceived and designed the study|acquired the data|quantified the data|analysed and interpreted the data|critically edited and revised the manuscript	analysed and interpreted the data	Analyzed the data	Formal analysis	YES
3570346	23136853	MCG	2	conceived and designed the study|acquired the data|quantified the data|analysed and interpreted the data|critically edited and revised the manuscript	critically edited and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
3570346	23136853	MQ	2	acquired the data|quantified the data|critically edited and revised the manuscript	acquired the data	Performed the experiments	Investigation	YES
3570346	23136853	MQ	2	acquired the data|quantified the data|critically edited and revised the manuscript	quantified the data	-	-	NO
3570346	23136853	MQ	2	acquired the data|quantified the data|critically edited and revised the manuscript	critically edited and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
3570346	23136853	PB	2	conceived and designed the study|acquired the data|quantified the data|critically edited and revised the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3570346	23136853	PB	2	conceived and designed the study|acquired the data|quantified the data|critically edited and revised the manuscript	acquired the data	Performed the experiments	Investigation	YES
3570346	23136853	PB	2	conceived and designed the study|acquired the data|quantified the data|critically edited and revised the manuscript	quantified the data	-	-	NO
3570346	23136853	PB	2	conceived and designed the study|acquired the data|quantified the data|critically edited and revised the manuscript	critically edited and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
3570346	23136853	PDC	2	conceived and designed the study|acquired the data|quantified the data|analysed and interpreted the data|wrote the manuscript|critically edited and revised the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3570346	23136853	PDC	2	conceived and designed the study|acquired the data|quantified the data|analysed and interpreted the data|wrote the manuscript|critically edited and revised the manuscript	acquired the data	Performed the experiments	Investigation	YES
3570346	23136853	PDC	2	conceived and designed the study|acquired the data|quantified the data|analysed and interpreted the data|wrote the manuscript|critically edited and revised the manuscript	quantified the data	-	-	NO
3570346	23136853	PDC	2	conceived and designed the study|acquired the data|quantified the data|analysed and interpreted the data|wrote the manuscript|critically edited and revised the manuscript	analysed and interpreted the data	Analyzed the data	Formal analysis	YES
3570346	23136853	PDC	2	conceived and designed the study|acquired the data|quantified the data|analysed and interpreted the data|wrote the manuscript|critically edited and revised the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3570346	23136853	PDC	2	conceived and designed the study|acquired the data|quantified the data|analysed and interpreted the data|wrote the manuscript|critically edited and revised the manuscript	critically edited and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
3570346	23136853	SD	2	conceived and designed the study|acquired the data|quantified the data|analysed and interpreted the data|wrote the manuscript|critically edited and revised the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3570346	23136853	SD	2	conceived and designed the study|acquired the data|quantified the data|analysed and interpreted the data|wrote the manuscript|critically edited and revised the manuscript	acquired the data	Performed the experiments	Investigation	YES
3570346	23136853	SD	2	conceived and designed the study|acquired the data|quantified the data|analysed and interpreted the data|wrote the manuscript|critically edited and revised the manuscript	quantified the data	-	-	NO
3570346	23136853	SD	2	conceived and designed the study|acquired the data|quantified the data|analysed and interpreted the data|wrote the manuscript|critically edited and revised the manuscript	analysed and interpreted the data	Analyzed the data	Formal analysis	YES
3570346	23136853	SD	2	conceived and designed the study|acquired the data|quantified the data|analysed and interpreted the data|wrote the manuscript|critically edited and revised the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3570346	23136853	SD	2	conceived and designed the study|acquired the data|quantified the data|analysed and interpreted the data|wrote the manuscript|critically edited and revised the manuscript	critically edited and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
3570346	23136853	TP	2	validated and synthesised the tracer|quantified the data|critically edited and revised the manuscript	validated and synthesised the tracer	Performed the experiments	Validation	YES
3570346	23136853	TP	2	validated and synthesised the tracer|quantified the data|critically edited and revised the manuscript	quantified the data	-	-	NO
3570346	23136853	TP	2	validated and synthesised the tracer|quantified the data|critically edited and revised the manuscript	critically edited and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5623178	29018472	BG	2	designed the experiment|helped with the with	designed the experiment	Conceived and designed the experiments	Methodology	YES
5623178	29018472	BG	2	designed the experiment|helped with the with	helped with the with	-	-	NO
5623178	29018472	CD	2	helped with the with	helped with the with	-	-	NO
5623178	29018472	CF	2	designed the experiment|helped with the with	designed the experiment	Conceived and designed the experiments	Methodology	YES
5623178	29018472	CF	2	designed the experiment|helped with the with	helped with the with	-	-	NO
5623178	29018472	GT	2	designed the experiment|helped with the with	designed the experiment	Conceived and designed the experiments	Methodology	YES
5623178	29018472	GT	2	designed the experiment|helped with the with	helped with the with	-	-	NO
5623178	29018472	MG	2	designed the experiment|conducted the experiments, with|analyzed the data and wrote the manuscript with contributions from all the authors	designed the experiment	Conceived and designed the experiments	Methodology	YES
5623178	29018472	MG	2	designed the experiment|conducted the experiments, with|analyzed the data and wrote the manuscript with contributions from all the authors	conducted the experiments, with	Performed the experiments	Investigation	YES
5623178	29018472	MG	2	designed the experiment|conducted the experiments, with|analyzed the data and wrote the manuscript with contributions from all the authors	analyzed the data and wrote the manuscript with contributions from all the authors	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4409215	25909630	HLS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409215	25909630	HLS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409215	25909630	HLS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409215	25909630	HLS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409215	25909630	HLS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409215	25909630	PAN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409215	25909630	PAN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409215	25909630	PAN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409215	25909630	PAN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5978645	29130601	AC	2	developed and finalized the manuscript	developed and finalized the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5978645	29130601	AE	2	developed and finalized the manuscript	developed and finalized the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5978645	29130601	BA	2	developed and finalized the manuscript	developed and finalized the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5978645	29130601	CZ	2	developed and finalized the manuscript	developed and finalized the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5978645	29130601	IJ	2	developed and finalized the manuscript	developed and finalized the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5978645	29130601	LV	2	developed and finalized the manuscript	developed and finalized the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5978645	29130601	ND	2	developed and finalized the manuscript	developed and finalized the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5978645	29130601	TP	2	developed and finalized the manuscript	developed and finalized the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5978645	29130601	ZK	2	developed and finalized the manuscript	developed and finalized the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3731795	23919092	Bhadra Brown	7	statistical analysis and interpretation, critical revision/drafting of the manuscript, final approval to submit. M	statistical analysis and interpretation, critical revision/drafting of the manuscript, final approval to submit. M	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
3731795	23919092	H. Sands	7	conduct of study, analysis and interpretation of data, critical revision/drafting of the manuscript, final approval to submit. P	conduct of study, analysis and interpretation of data, critical revision/drafting of the manuscript, final approval to submit. P	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
3731795	23919092	Noyes Essex	7	analysis and interpretation of data, critical revision/drafting of the manuscript, final approval to submit	analysis and interpretation of data, critical revision/drafting of the manuscript, final approval to submit	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
4538413	26339614	All authors	2	participated in preparation of this paper	participated in preparation of this paper	-	-	NO
5436462	28521784	JL	2	designed this study, developed the statistical methods and wrote the manuscript	designed this study, developed the statistical methods and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5436462	28521784	KLX	2	designed this study, developed the statistical methods and wrote the manuscript|wrote the r package and performed data analysis	designed this study, developed the statistical methods and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5436462	28521784	KLX	2	designed this study, developed the statistical methods and wrote the manuscript|wrote the r package and performed data analysis	wrote the r package and performed data analysis	Analyzed the data|Wrote the paper	Formal analysis|Software|Writing - Original Draft	YES
5436462	28521784	MMX	2	designed this study, developed the statistical methods and wrote the manuscript	designed this study, developed the statistical methods and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5489582	28577046	All of the authors	2	contributed to the manuscript drafts, and reviewed and approved the final manuscript	contributed to the manuscript drafts, and reviewed and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3570351	23311872	CLM	2	prepared the radiotracers and performed the hplc measurements	prepared the radiotracers and performed the hplc measurements	Performed the experiments	Investigation	YES
3570351	23311872	HUS	2	designed the experiments and wrote the manuscript|conceived the study and interpreted the data	designed the experiments and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3570351	23311872	HUS	2	designed the experiments and wrote the manuscript|conceived the study and interpreted the data	conceived the study and interpreted the data	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
3570351	23311872	MS	2	processed the data	processed the data	Analyzed the data	Data curation	YES
3570351	23311872	VWP	2	designed the experiments and wrote the manuscript	designed the experiments and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3570351	23311872	YZ	2	prepared the radiotracers and performed the hplc measurements	prepared the radiotracers and performed the hplc measurements	Performed the experiments	Investigation	YES
4409217	25909856	AMF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409217	25909856	AMF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409217	25909856	AMF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409217	25909856	AMF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409217	25909856	AMF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409217	25909856	BH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409217	25909856	BH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409217	25909856	BH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409217	25909856	BH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409217	25909856	BH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409217	25909856	LIG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409217	25909856	LIG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409217	25909856	LIG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409217	25909856	LIG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409217	25909856	LIG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409217	25909856	MJK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409217	25909856	MJK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409217	25909856	MJK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409217	25909856	MJK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409217	25909856	MJK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409217	25909856	PMW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409217	25909856	PMW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409217	25909856	PMW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409217	25909856	TER	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409217	25909856	TER	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409217	25909856	TER	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5978652	29171193	ACV	2	conceptualized and drafted the manuscript|provided critical inputs in the draft manuscript	conceptualized and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5978652	29171193	ACV	2	conceptualized and drafted the manuscript|provided critical inputs in the draft manuscript	provided critical inputs in the draft manuscript	Wrote the paper	Writing - Original Draft	YES
5978652	29171193	BP	2	provided critical inputs in the draft manuscript	provided critical inputs in the draft manuscript	Wrote the paper	Writing - Original Draft	YES
5978652	29171193	CM	2	provided critical inputs in the draft manuscript	provided critical inputs in the draft manuscript	Wrote the paper	Writing - Original Draft	YES
5978652	29171193	CN	2	provided critical inputs in the draft manuscript	provided critical inputs in the draft manuscript	Wrote the paper	Writing - Original Draft	YES
5978652	29171193	FC	2	provided critical inputs in the draft manuscript	provided critical inputs in the draft manuscript	Wrote the paper	Writing - Original Draft	YES
5978652	29171193	FMO	2	provided critical inputs in the draft manuscript	provided critical inputs in the draft manuscript	Wrote the paper	Writing - Original Draft	YES
5978652	29171193	GC	2	provided critical inputs in the draft manuscript	provided critical inputs in the draft manuscript	Wrote the paper	Writing - Original Draft	YES
5978652	29171193	HM	2	provided critical inputs in the draft manuscript	provided critical inputs in the draft manuscript	Wrote the paper	Writing - Original Draft	YES
5978652	29171193	HP	2	provided critical inputs in the draft manuscript	provided critical inputs in the draft manuscript	Wrote the paper	Writing - Original Draft	YES
5978652	29171193	JEJ	2	conceptualized and drafted the manuscript|provided critical inputs in the draft manuscript	conceptualized and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5978652	29171193	JEJ	2	conceptualized and drafted the manuscript|provided critical inputs in the draft manuscript	provided critical inputs in the draft manuscript	Wrote the paper	Writing - Original Draft	YES
5978652	29171193	JM	2	provided critical inputs in the draft manuscript	provided critical inputs in the draft manuscript	Wrote the paper	Writing - Original Draft	YES
5978652	29171193	KL	2	conducted the data analysis	conducted the data analysis	Analyzed the data	Formal analysis	YES
5978652	29171193	KS	2	provided critical inputs in the draft manuscript	provided critical inputs in the draft manuscript	Wrote the paper	Writing - Original Draft	YES
5978652	29171193	MM	2	conceptualized and drafted the manuscript|conducted the data analysis	conceptualized and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5978652	29171193	MM	2	conceptualized and drafted the manuscript|conducted the data analysis	conducted the data analysis	Analyzed the data	Formal analysis	YES
5978652	29171193	NSV	2	provided critical inputs in the draft manuscript	provided critical inputs in the draft manuscript	Wrote the paper	Writing - Original Draft	YES
5978652	29171193	OM	2	provided critical inputs in the draft manuscript	provided critical inputs in the draft manuscript	Wrote the paper	Writing - Original Draft	YES
5978652	29171193	RM	2	provided critical inputs in the draft manuscript	provided critical inputs in the draft manuscript	Wrote the paper	Writing - Original Draft	YES
5978652	29171193	SS	2	conceptualized and drafted the manuscript|conducted the data analysis	conceptualized and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5978652	29171193	SS	2	conceptualized and drafted the manuscript|conducted the data analysis	conducted the data analysis	Analyzed the data	Formal analysis	YES
5978652	29171193	TN	2	provided critical inputs in the draft manuscript	provided critical inputs in the draft manuscript	Wrote the paper	Writing - Original Draft	YES
5978652	29171193	VM	2	provided critical inputs in the draft manuscript	provided critical inputs in the draft manuscript	Wrote the paper	Writing - Original Draft	YES
5978652	29171193	WK	2	provided critical inputs in the draft manuscript	provided critical inputs in the draft manuscript	Wrote the paper	Writing - Original Draft	YES
5978652	29171193	YTD	2	conceptualized and drafted the manuscript	conceptualized and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5623184	29018458	All of the authors	PLoS52	read and approved the manuscript	read and approved the manuscript	-	-	NO
5623184	29018458	DY	PLoS52	carried out phenotyping and genotyping|managed the project|analyzed the data	carried out phenotyping and genotyping	Performed the experiments	Investigation	YES
5623184	29018458	DY	PLoS52	carried out phenotyping and genotyping|managed the project|analyzed the data	managed the project	-	Project administration	YES
5623184	29018458	DY	PLoS52	carried out phenotyping and genotyping|managed the project|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5623184	29018458	JZ	PLoS52	carried out phenotyping and genotyping	carried out phenotyping and genotyping	Performed the experiments	Investigation	YES
5623184	29018458	XH	PLoS52	carried out phenotyping and genotyping	carried out phenotyping and genotyping	Performed the experiments	Investigation	YES
5623184	29018458	XM	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5623184	29018458	XZ	PLoS52	carried out phenotyping and genotyping|managed the project|analyzed the data|wrote the paper	carried out phenotyping and genotyping	Performed the experiments	Investigation	YES
5623184	29018458	XZ	PLoS52	carried out phenotyping and genotyping|managed the project|analyzed the data|wrote the paper	managed the project	-	Project administration	YES
5623184	29018458	XZ	PLoS52	carried out phenotyping and genotyping|managed the project|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5623184	29018458	XZ	PLoS52	carried out phenotyping and genotyping|managed the project|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5623184	29018458	YW	PLoS52	managed the project	managed the project	-	Project administration	YES
1762431	17205113	AO	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Responsible for the english language of the paper and correspondence	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762431	17205113	AO	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Responsible for the english language of the paper and correspondence	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762431	17205113	AO	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Responsible for the english language of the paper and correspondence	Responsible for the english language of the paper and correspondence	-	-	NO
1762431	17205113	LK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762431	17205113	LK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762431	17205113	LK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762431	17205113	LK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762431	17205113	LK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3570487	23384286	JED	2	participated in the design of the study and in the analysis and interpretation of data	participated in the design of the study and in the analysis and interpretation of data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
3570487	23384286	LE	2	participated in the design of the study and in the analysis and interpretation of data, and drafted the manuscript	participated in the design of the study and in the analysis and interpretation of data, and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3570487	23384286	ML	2	participated in the design of the study and in the analysis and interpretation of data	participated in the design of the study and in the analysis and interpretation of data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
3570487	23384286	MO	2	carried out the analysis of data	carried out the analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3570487	23384286	PG	2	participated in the design of the study and in the analysis and interpretation of data	participated in the design of the study and in the analysis and interpretation of data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
3570487	23384286	PH	2	carried out the analysis of data	carried out the analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3570487	23384286	RK	2	participated in the design of the study and in the analysis and interpretation of data, and drafted the manuscript	participated in the design of the study and in the analysis and interpretation of data, and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5623187	29018470	AN	2	conceived, planned, and designed the research, and wrote the manuscript|performed the experiments involving gas exchange and carbohydrates dynamics	conceived, planned, and designed the research, and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
5623187	29018470	AN	2	conceived, planned, and designed the research, and wrote the manuscript|performed the experiments involving gas exchange and carbohydrates dynamics	performed the experiments involving gas exchange and carbohydrates dynamics	Performed the experiments	Investigation	YES
5623187	29018470	All authors	2	reviewed the final version of the manuscript	reviewed the final version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5623187	29018470	BA	2	was responsible for design and interpretation of histopathological experiments	was responsible for design and interpretation of histopathological experiments	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5623187	29018470	JR	2	performed the optical and electron microscopy	performed the optical and electron microscopy	Performed the experiments	Investigation	YES
5623187	29018470	LA	2	conceived, planned, and designed the research, and wrote the manuscript	conceived, planned, and designed the research, and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
5623187	29018470	MS	2	performed the optical and electron microscopy	performed the optical and electron microscopy	Performed the experiments	Investigation	YES
5623187	29018470	RR	2	conceived, planned, and designed the research, and wrote the manuscript	conceived, planned, and designed the research, and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
5623187	29018470	The authors	2	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	Performed the experiments	Investigation	YES
4538414	26339629	Young Lee	2	contributed equally to this work	contributed equally to this work	-	-	NO
4538414	26339629	Youngdoe Kim	2	contributed equally to this work	contributed equally to this work	-	-	NO
5978653	29485744	CW	2	reviewed all articles in the special issue, and formulated, drafted and developed the editorial	reviewed all articles in the special issue, and formulated, drafted and developed the editorial	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
5978653	29485744	DW	2	reviewed all articles in the special issue, and formulated, drafted and developed the editorial	reviewed all articles in the special issue, and formulated, drafted and developed the editorial	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
5978653	29485744	LC	2	reviewed all articles in the special issue, and formulated, drafted and developed the editorial	reviewed all articles in the special issue, and formulated, drafted and developed the editorial	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
4409218	25910249	AE	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4409218	25910249	AE	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409218	25910249	FL	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409218	25910249	FP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409218	25910249	FP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409218	25910249	FP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409218	25910249	HP	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409218	25910249	MJ	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409218	25910249	MJ	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409218	25910249	RP	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409218	25910249	RP	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409218	25910249	SV	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5437397	28521727	AAA	2	conceived and designed the study|finalised the data, wrote the manuscript and approved the final manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5437397	28521727	AAA	2	conceived and designed the study|finalised the data, wrote the manuscript and approved the final manuscript	finalised the data, wrote the manuscript and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5437397	28521727	AGL	2	conceived and designed the study|performed the experiments and data analyses|finalised the data, wrote the manuscript and approved the final manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5437397	28521727	AGL	2	conceived and designed the study|performed the experiments and data analyses|finalised the data, wrote the manuscript and approved the final manuscript	performed the experiments and data analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5437397	28521727	AGL	2	conceived and designed the study|performed the experiments and data analyses|finalised the data, wrote the manuscript and approved the final manuscript	finalised the data, wrote the manuscript and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3579699	23369630	CW	2	designed the study, performed the experiments, analysed and interpreted the data, and drafted and revised the manuscript	designed the study, performed the experiments, analysed and interpreted the data, and drafted and revised the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
3579699	23369630	FJB	2	conceived of and designed the study, participated in its coordination and drafted and revised the manuscript	conceived of and designed the study, participated in its coordination and drafted and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft|Writing - Review & Editing	YES
3579699	23369630	HAGvA	2	analysed and interpreted the data and revised the manuscript	analysed and interpreted the data and revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
3579699	23369630	OCB	2	participated in the study design and coordination and revised the manuscript	participated in the study design and coordination and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Review & Editing	YES
3579699	23369630	PL	2	co-performed the experiments and revised the manuscript	co-performed the experiments and revised the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5978654	29633561	JF	2	critically reviewed the manuscript and provided input accordingly	critically reviewed the manuscript and provided input accordingly	Wrote the paper	Writing - Review & Editing	YES
5978654	29633561	NL	2	wrote the draft of the outline|critically reviewed the manuscript and provided input accordingly	wrote the draft of the outline	Wrote the paper	Writing - Original Draft	YES
5978654	29633561	NL	2	wrote the draft of the outline|critically reviewed the manuscript and provided input accordingly	critically reviewed the manuscript and provided input accordingly	Wrote the paper	Writing - Review & Editing	YES
5978654	29633561	SC	2	critically reviewed the manuscript and provided input accordingly	critically reviewed the manuscript and provided input accordingly	Wrote the paper	Writing - Review & Editing	YES
5978654	29633561	SF	2	wrote the draft of the outline|wrote the first draft of the manuscript	wrote the draft of the outline	Wrote the paper	Writing - Original Draft	YES
5978654	29633561	SF	2	wrote the draft of the outline|wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
1762432	17205116	AE	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1762432	17205116	BM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762432	17205116	BM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762432	17205116	BM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762432	17205116	BM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5623194	29018473	AJM	2	conceived, designed and coordinated the study, and helped to draft the manuscript	conceived, designed and coordinated the study, and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
5623194	29018473	JA	2	performed qpcr analyses and drafted the manuscript	performed qpcr analyses and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5623194	29018473	JG	2	conceived, designed and coordinated the study, and helped to draft the manuscript	conceived, designed and coordinated the study, and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
5623194	29018473	VAL	2	provided analyses and access to additional data	provided analyses and access to additional data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5623194	29018473	VR	2	performed the resequencing and variant analyses	performed the resequencing and variant analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5623194	29018473	YG	2	performed the analyses of soluble sugars and organic acids, and interpretation of data	performed the analyses of soluble sugars and organic acids, and interpretation of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3598556	23442595	AN	2	participated in acquiring, analyzing, and interpreting the data, drafting the manuscript	participated in acquiring, analyzing, and interpreting the data, drafting the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3598556	23442595	AR	2	participated in analyzing and interpreting the data, drafting and revising the manuscript and enhancing its intellectual content, obtaining financing for the study	participated in analyzing and interpreting the data, drafting and revising the manuscript and enhancing its intellectual content, obtaining financing for the study	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
3598556	23442595	HK	2	participated in performing the histopathological analysis and drafting the manuscript	participated in performing the histopathological analysis and drafting the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3598556	23442595	HN	2	participated in recruiting the patients|participated in recruiting the patients, drafting the manuscript	participated in recruiting the patients	Performed the experiments	Investigation	YES
3598556	23442595	HN	2	participated in recruiting the patients|participated in recruiting the patients, drafting the manuscript	participated in recruiting the patients, drafting the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3598556	23442595	JO	2	participated in acquiring the data and drafting the manuscript	participated in acquiring the data and drafting the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3598556	23442595	JV	2	participated in interpreting the mri data and drafting the manuscript	participated in interpreting the mri data and drafting the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3598556	23442595	MK	2	participated in performing the histopathological analysis and drafting the manuscript	participated in performing the histopathological analysis and drafting the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3598556	23442595	MS	2	contributed to the study concept and design and participated in acquiring, analyzing, and interpreting the data and revising the manuscript	contributed to the study concept and design and participated in acquiring, analyzing, and interpreting the data and revising the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Resources|Writing - Review & Editing	YES
3598556	23442595	PR	2	participated in interpreting the data and revising the manuscript	participated in interpreting the data and revising the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
3598556	23442595	RL	2	participated in recruiting the patients, drafting the manuscript	participated in recruiting the patients, drafting the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3598556	23442595	RP	2	participated in interpreting the mri data and drafting the manuscript	participated in interpreting the mri data and drafting the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4409220	25909513	JC	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409220	25909513	JO	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4409220	25909513	JO	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4409220	25909513	JO	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409220	25909513	JZ	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409220	25909513	MP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409220	25909513	PS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409220	25909513	PS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409220	25909513	PS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409220	25909513	RW	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409220	25909513	RW	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5437419	28521734	AK	2	designed the study and performed laboratory experiments|carried out bioinformatic analysis|co-drafted the manuscript	designed the study and performed laboratory experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5437419	28521734	AK	2	designed the study and performed laboratory experiments|carried out bioinformatic analysis|co-drafted the manuscript	carried out bioinformatic analysis	Performed the experiments	Formal analysis|Investigation	YES
5437419	28521734	AK	2	designed the study and performed laboratory experiments|carried out bioinformatic analysis|co-drafted the manuscript	co-drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5437419	28521734	GD	2	provided e|co-drafted the manuscript	provided e	-	-	NO
5437419	28521734	GD	2	provided e|co-drafted the manuscript	co-drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5437419	28521734	KO	2	performed fish with 5s rdna and data analysis|co-drafted the manuscript	performed fish with 5s rdna and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5437419	28521734	KO	2	performed fish with 5s rdna and data analysis|co-drafted the manuscript	co-drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5437419	28521734	LK	2	performed fish with 5s rdna and data analysis	performed fish with 5s rdna and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5437419	28521734	RS	2	designed the study and performed laboratory experiments|collected biological material and prepared microscopic samples|carried out bioinformatic analysis|co-drafted the manuscript	designed the study and performed laboratory experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5437419	28521734	RS	2	designed the study and performed laboratory experiments|collected biological material and prepared microscopic samples|carried out bioinformatic analysis|co-drafted the manuscript	collected biological material and prepared microscopic samples	Performed the experiments	Investigation	YES
5437419	28521734	RS	2	designed the study and performed laboratory experiments|collected biological material and prepared microscopic samples|carried out bioinformatic analysis|co-drafted the manuscript	carried out bioinformatic analysis	Performed the experiments	Formal analysis|Investigation	YES
5437419	28521734	RS	2	designed the study and performed laboratory experiments|collected biological material and prepared microscopic samples|carried out bioinformatic analysis|co-drafted the manuscript	co-drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5437419	28521734	SG	2	carried out bioinformatic analysis	carried out bioinformatic analysis	Performed the experiments	Formal analysis|Investigation	YES
5437419	28521734	SP	2	collected biological material and prepared microscopic samples	collected biological material and prepared microscopic samples	Performed the experiments	Investigation	YES
5437419	28521734	all authors	2	read the manuscript	read the manuscript	-	-	NO
5978657	29633562	All authors	2	reviewed the full draft of the article and approved the final version for submission	reviewed the full draft of the article and approved the final version for submission	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5978657	29633562	GH	2	were part of the hep-core study group and contributed to the development of the original study instrument as well as providing input on the article	were part of the hep-core study group and contributed to the development of the original study instrument as well as providing input on the article	Wrote the paper	Writing - Original Draft	YES
5978657	29633562	JT	2	were part of the hep-core study group and contributed to the development of the original study instrument as well as providing input on the article	were part of the hep-core study group and contributed to the development of the original study instrument as well as providing input on the article	Wrote the paper	Writing - Original Draft	YES
5978657	29633562	JVL	2	was the hep-core studys principal investigator|drafted the article with input from the co-authors	was the hep-core studys principal investigator	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
5978657	29633562	JVL	2	was the hep-core studys principal investigator|drafted the article with input from the co-authors	drafted the article with input from the co-authors	Wrote the paper	Writing - Original Draft	YES
5978657	29633562	KS	2	were part of the hep-core study group and contributed to the development of the original study instrument as well as providing input on the article	were part of the hep-core study group and contributed to the development of the original study instrument as well as providing input on the article	Wrote the paper	Writing - Original Draft	YES
5978657	29633562	KSH	2	drafted the article with input from the co-authors	drafted the article with input from the co-authors	Wrote the paper	Writing - Original Draft	YES
5978657	29633562	MH	2	were part of the hep-core study group and contributed to the development of the original study instrument as well as providing input on the article	were part of the hep-core study group and contributed to the development of the original study instrument as well as providing input on the article	Wrote the paper	Writing - Original Draft	YES
5978657	29633562	MJR	2	were part of the hep-core study group and contributed to the development of the original study instrument as well as providing input on the article	were part of the hep-core study group and contributed to the development of the original study instrument as well as providing input on the article	Wrote the paper	Writing - Original Draft	YES
5978657	29633562	MM	2	were part of the hep-core study group and contributed to the development of the original study instrument as well as providing input on the article	were part of the hep-core study group and contributed to the development of the original study instrument as well as providing input on the article	Wrote the paper	Writing - Original Draft	YES
5978657	29633562	SRS	2	drafted the article with input from the co-authors|as the data manager	drafted the article with input from the co-authors	Wrote the paper	Writing - Original Draft	YES
5978657	29633562	SRS	2	drafted the article with input from the co-authors|as the data manager	as the data manager	Analyzed the data	Data curation|Project administration	YES
5978657	29633562	TR	2	were part of the hep-core study group and contributed to the development of the original study instrument as well as providing input on the article	were part of the hep-core study group and contributed to the development of the original study instrument as well as providing input on the article	Wrote the paper	Writing - Original Draft	YES
3598640	23272995	Each author	5	has contributed significantly to the submitted work: VR: design	has contributed significantly to the submitted work: VR: design	Conceived and designed the experiments	-	YES
3743639	23966804	AB	2	were responsible for model testing of mechanical ventilators and simulation training sessions|reviewed the study and this manuscript	were responsible for model testing of mechanical ventilators and simulation training sessions	Performed the experiments	Formal analysis|Investigation|Methodology	YES
3743639	23966804	AB	2	were responsible for model testing of mechanical ventilators and simulation training sessions|reviewed the study and this manuscript	reviewed the study and this manuscript	Wrote the paper	Writing - Review & Editing	YES
3743639	23966804	AC	2	chief investigator and coordinator for the medical section, conceived the study, participated in the design, and helped to draft the manuscript|were responsible for model testing of mechanical ventilators and simulation training sessions	chief investigator and coordinator for the medical section, conceived the study, participated in the design, and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
3743639	23966804	AC	2	chief investigator and coordinator for the medical section, conceived the study, participated in the design, and helped to draft the manuscript|were responsible for model testing of mechanical ventilators and simulation training sessions	were responsible for model testing of mechanical ventilators and simulation training sessions	Performed the experiments	Formal analysis|Investigation|Methodology	YES
3743639	23966804	AM	2	coordinated the engineering section	coordinated the engineering section	-	Project administration	YES
3743639	23966804	All authors	2	contributed to the development of the protocol and read and approved the final manuscript	contributed to the development of the protocol and read and approved the final manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft|Writing - Review & Editing	YES
3743639	23966804	CL	2	coordinated the engineering section	coordinated the engineering section	-	Project administration	YES
3743639	23966804	ES	2	were responsible for model testing of mechanical ventilators and simulation training sessions|reviewed the study and this manuscript	were responsible for model testing of mechanical ventilators and simulation training sessions	Performed the experiments	Formal analysis|Investigation|Methodology	YES
3743639	23966804	ES	2	were responsible for model testing of mechanical ventilators and simulation training sessions|reviewed the study and this manuscript	reviewed the study and this manuscript	Wrote the paper	Writing - Review & Editing	YES
3743639	23966804	FC	2	participated in the study design and are responsible for data collection and draft coordination/writing|created the figures for this manuscript	participated in the study design and are responsible for data collection and draft coordination/writing	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Project administration|Writing - Original Draft	YES
3743639	23966804	FC	2	participated in the study design and are responsible for data collection and draft coordination/writing|created the figures for this manuscript	created the figures for this manuscript	-	Visualization	YES
3743639	23966804	IB	2	were responsible for materials and software development	were responsible for materials and software development	Contributed reagents/materials/analysis tools	Software	YES
3743639	23966804	LB	2	were responsible for materials and software development	were responsible for materials and software development	Contributed reagents/materials/analysis tools	Software	YES
3743639	23966804	MC	2	participated in the study design and are responsible for data collection and draft coordination/writing|were responsible for research on physiology and pathophysiology of the newborn respiratory system|were responsible for model testing of mechanical ventilators and simulation training sessions	participated in the study design and are responsible for data collection and draft coordination/writing	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Project administration|Writing - Original Draft	YES
3743639	23966804	MC	2	participated in the study design and are responsible for data collection and draft coordination/writing|were responsible for research on physiology and pathophysiology of the newborn respiratory system|were responsible for model testing of mechanical ventilators and simulation training sessions	were responsible for research on physiology and pathophysiology of the newborn respiratory system	-	-	NO
3743639	23966804	MC	2	participated in the study design and are responsible for data collection and draft coordination/writing|were responsible for research on physiology and pathophysiology of the newborn respiratory system|were responsible for model testing of mechanical ventilators and simulation training sessions	were responsible for model testing of mechanical ventilators and simulation training sessions	Performed the experiments	Formal analysis|Investigation|Methodology	YES
3743639	23966804	MG	2	participated in the study design and are responsible for data collection and draft coordination/writing|were responsible for research on physiology and pathophysiology of the newborn respiratory system	participated in the study design and are responsible for data collection and draft coordination/writing	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Project administration|Writing - Original Draft	YES
3743639	23966804	MG	2	participated in the study design and are responsible for data collection and draft coordination/writing|were responsible for research on physiology and pathophysiology of the newborn respiratory system	were responsible for research on physiology and pathophysiology of the newborn respiratory system	-	-	NO
3743639	23966804	NINA	2	located inside the neonatal care unit of pisa hospital	located inside the neonatal care unit of pisa hospital	-	-	NO
3743639	23966804	PD	2	coordinated the engineering section	coordinated the engineering section	-	Project administration	YES
3743639	23966804	PG	2	reviewed the study and this manuscript	reviewed the study and this manuscript	Wrote the paper	Writing - Review & Editing	YES
3743639	23966804	RTS	2	participated in the study design and are responsible for data collection and draft coordination/writing|were responsible for research on physiology and pathophysiology of the newborn respiratory system	participated in the study design and are responsible for data collection and draft coordination/writing	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Project administration|Writing - Original Draft	YES
3743639	23966804	RTS	2	participated in the study design and are responsible for data collection and draft coordination/writing|were responsible for research on physiology and pathophysiology of the newborn respiratory system	were responsible for research on physiology and pathophysiology of the newborn respiratory system	-	-	NO
3743639	23966804	SM	2	are responsible for the prototype and testing phase, as well as revising the manuscript	are responsible for the prototype and testing phase, as well as revising the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
3743639	23966804	ST	2	participated in the study design and are responsible for data collection and draft coordination/writing|created the figures for this manuscript	participated in the study design and are responsible for data collection and draft coordination/writing	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Project administration|Writing - Original Draft	YES
3743639	23966804	ST	2	participated in the study design and are responsible for data collection and draft coordination/writing|created the figures for this manuscript	created the figures for this manuscript	-	Visualization	YES
3743639	23966804	Simulazione Neonatale	2	located inside the neonatal care unit of pisa hospital	located inside the neonatal care unit of pisa hospital	-	-	NO
3743639	23966804	Superiore SantAnna	2	which has expertise in the design and development of surgical, diagnostic, and therapeutic robotic systems and microtechnologies for medical applications	which has expertise in the design and development of surgical, diagnostic, and therapeutic robotic systems and microtechnologies for medical applications	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4409221	25909470	JLM	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409221	25909470	JW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409221	25909470	JW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409221	25909470	JW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409221	25909470	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409221	25909470	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409221	25909470	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409221	25909470	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409221	25909470	MSK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409221	25909470	TT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409221	25909470	TT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409221	25909470	TT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409221	25909470	TT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762433	17205132	DA	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762433	17205132	FM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1762433	17205132	FM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762433	17205132	HO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762433	17205132	HO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1762433	17205132	HO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1762433	17205132	HO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762433	17205132	JP	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762433	17205132	JP	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762433	17205132	OT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762433	17205132	OT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762433	17205132	OT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762433	17205132	OT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762433	17205132	OT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762433	17205132	SL	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762433	17205132	SL	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5623719	29021806	XQ	PLoS52	designed the experiments, analyzed the data and wrote the paper|performed the experiments	designed the experiments, analyzed the data and wrote the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5623719	29021806	XQ	PLoS52	designed the experiments, analyzed the data and wrote the paper|performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5623719	29021806	ZT	PLoS52	designed the experiments, analyzed the data and wrote the paper	designed the experiments, analyzed the data and wrote the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5623719	29021806	ZZ	PLoS52	designed the experiments, analyzed the data and wrote the paper	designed the experiments, analyzed the data and wrote the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5437515	28521747	JHJN	PLoS52	conceived and designed the study|performed the experiments|analysed and discussed the data|wrote the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5437515	28521747	JHJN	PLoS52	conceived and designed the study|performed the experiments|analysed and discussed the data|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5437515	28521747	JHJN	PLoS52	conceived and designed the study|performed the experiments|analysed and discussed the data|wrote the manuscript	analysed and discussed the data	Analyzed the data	Formal analysis	YES
5437515	28521747	JHJN	PLoS52	conceived and designed the study|performed the experiments|analysed and discussed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5437515	28521747	L-FW	PLoS52	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5437515	28521747	MLB	PLoS52	conceived and designed the study|analysed and discussed the data|wrote the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5437515	28521747	MLB	PLoS52	conceived and designed the study|analysed and discussed the data|wrote the manuscript	analysed and discussed the data	Analyzed the data	Formal analysis	YES
5437515	28521747	MLB	PLoS52	conceived and designed the study|analysed and discussed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5437515	28521747	MT	PLoS52	performed the experiments|analysed and discussed the data	performed the experiments	Performed the experiments	Investigation	YES
5437515	28521747	MT	PLoS52	performed the experiments|analysed and discussed the data	analysed and discussed the data	Analyzed the data	Formal analysis	YES
5978658	29130621	All authors	2	contributed equally to the writing and editing of this manuscript	contributed equally to the writing and editing of this manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3598883	22978819	All authors	2	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
3598883	22978819	FH	2	performed part of the data analysis	performed part of the data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3598883	22978819	JS	2	provided intellectual input	provided intellectual input	-	-	NO
3598883	22978819	JvdH	2	formulated the modeling part of this work and supported the discussion with his experience and knowledge of the subject	formulated the modeling part of this work and supported the discussion with his experience and knowledge of the subject	Conceived and designed the experiments|Performed the experiments	Conceptualization|Methodology	YES
3598883	22978819	KS	2	initially tested the sequence used for asl measurements	initially tested the sequence used for asl measurements	Performed the experiments	Investigation	YES
1762434	17205118	AD	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762434	17205118	AD	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762434	17205118	CC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1762434	17205118	EL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762434	17205118	EL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762434	17205118	EL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762434	17205118	EL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762434	17205118	JK	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1762434	17205118	JK	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762434	17205118	KB	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762434	17205118	MH	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1762434	17205118	MH	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762434	17205118	RL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1762434	17205118	RL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1762434	17205118	RL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762434	17205118	TH	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1762434	17205118	TH	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762434	17205118	WF	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762434	17205118	WF	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3599195	23442550	CT	2	imaging, image reconstruction, data analysis, and drafted the manuscript|imaging and revised the manuscript	imaging, image reconstruction, data analysis, and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Visualization|Writing - Original Draft	YES
3599195	23442550	CT	2	imaging, image reconstruction, data analysis, and drafted the manuscript|imaging and revised the manuscript	imaging and revised the manuscript	Analyzed the data|Wrote the paper	Visualization|Writing - Review & Editing	YES
3599195	23442550	GE	2	participated in the study design, functionalized the microbubbles, and revised the manuscript	participated in the study design, functionalized the microbubbles, and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
3599195	23442550	GP	2	participated in the study design and drafted the manuscript	participated in the study design and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3599195	23442550	KC	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
3599195	23442550	LD	2	participated in the study design, functionalized the microbubbles, and revised the manuscript	participated in the study design, functionalized the microbubbles, and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
3599195	23442550	LO	2	functionalized the microbubbles and revised the manuscript	functionalized the microbubbles and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
3599195	23442550	MH	2	designed the study, carried out animal experiments, performed data analysis, and finalized the manuscript	designed the study, carried out animal experiments, performed data analysis, and finalized the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Review & Editing	YES
3599195	23442550	PA	2	participated in the study design and drafted the manuscript	participated in the study design and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3599195	23442550	RA	2	participated in the study design, performed visual evaluation, and revised the manuscript	participated in the study design, performed visual evaluation, and revised the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Investigation|Methodology|Visualization|Writing - Review & Editing	YES
3599195	23442550	SM	2	functionalized the microbubbles and revised the manuscript	functionalized the microbubbles and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
3599195	23442550	TBB	2	participated in the study design and data analysis and drafted the manuscript	participated in the study design and data analysis and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5978659	29171192	EJA	2	conceptualized the paper	conceptualized the paper	Conceived and designed the experiments	Conceptualization	YES
5978659	29171192	TME	2	conceptualized the paper	conceptualized the paper	Conceived and designed the experiments	Conceptualization	YES
5978659	29171192	WMES	2	conceptualized the paper	conceptualized the paper	Conceived and designed the experiments	Conceptualization	YES
4538419	26339632	Shengyue Ji	2	contributed equally to this work	contributed equally to this work	-	-	NO
4538419	26339632	Weili Li	2	contributed equally to this work	contributed equally to this work	-	-	NO
4409222	25910040	DB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409222	25910040	DB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409222	25910040	DB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409222	25910040	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409222	25910040	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409222	25910040	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409222	25910040	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409222	25910040	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409222	25910040	TB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409222	25910040	TB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409222	25910040	TB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409222	25910040	TB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409222	25910040	TB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5437544	28521726	MPD	2	developed the algorithm|analysed the data and wrote the manuscript	developed the algorithm	Contributed reagents/materials/analysis tools	Software	YES
5437544	28521726	MPD	2	developed the algorithm|analysed the data and wrote the manuscript	analysed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5437544	28521726	SK	2	conceived the project|analysed the data and wrote the manuscript	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5437544	28521726	SK	2	conceived the project|analysed the data and wrote the manuscript	analysed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5623721	29021796	All authors	2	edited and commented on the manuscript	edited and commented on the manuscript	Wrote the paper	Writing - Review & Editing	YES
5623721	29021796	ST	2	provided the data and figures for the cytoscape analyses	provided the data and figures for the cytoscape analyses	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources|Visualization	YES
3599558	23406885	All authors	2	contributed to the writing and review of the reports and have read and approved the manuscript	contributed to the writing and review of the reports and have read and approved the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3599558	23406885	CM	2	drafted the research plan	drafted the research plan	Wrote the paper	Writing - Original Draft	YES
3599558	23406885	CYP	2	phenotyping, microsomal and hepatocyte incubations, and drafted the manuscript	phenotyping, microsomal and hepatocyte incubations, and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3599558	23406885	MES	2	conceived the project and assisted in the interpretation of results	conceived the project and assisted in the interpretation of results	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
3599558	23406885	RMS	2	selected the in vitro assays, reviewed and approved all results, and provided the interpretation of metabolic pathways	selected the in vitro assays, reviewed and approved all results, and provided the interpretation of metabolic pathways	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3599558	23406885	XL	2	contributed to experimental design and conducted supportive studies	contributed to experimental design and conducted supportive studies	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
1762435	17205120	BY	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762435	17205120	BY	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762435	17205120	CW	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762435	17205120	CW	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762435	17205120	CZ	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762435	17205120	DG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1762435	17205120	GC	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762435	17205120	JW	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762435	17205120	QL	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762435	17205120	QL	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1762435	17205120	WY	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762435	17205120	WY	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1762435	17205120	YJ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1762435	17205120	YZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762435	17205120	YZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762435	17205120	YZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762435	17205120	ZH	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762435	17205120	ZH	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5978660	29485735	AM	2	contributed significantly to data collection	contributed significantly to data collection	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5978660	29485735	DS	2	designed the study|contributed significantly to data collection	designed the study	Conceived and designed the experiments	Methodology	YES
5978660	29485735	DS	2	designed the study|contributed significantly to data collection	contributed significantly to data collection	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5978660	29485735	EH	2	designed the study|performed the analysis	designed the study	Conceived and designed the experiments	Methodology	YES
5978660	29485735	EH	2	designed the study|performed the analysis	performed the analysis	Performed the experiments	Investigation	YES
5978660	29485735	LM	2	contributed significantly to data collection	contributed significantly to data collection	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5978660	29485735	NU	2	contributed significantly to data collection	contributed significantly to data collection	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5978660	29485735	SC	2	designed the study|performed the analysis|wrote the first draft	designed the study	Conceived and designed the experiments	Methodology	YES
5978660	29485735	SC	2	designed the study|performed the analysis|wrote the first draft	performed the analysis	Performed the experiments	Investigation	YES
5978660	29485735	SC	2	designed the study|performed the analysis|wrote the first draft	wrote the first draft	Wrote the paper	Writing - Original Draft	YES
5978660	29485735	WF	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
4409223	25910236	CW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409223	25910236	CW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409223	25910236	CW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409223	25910236	DF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409223	25910236	DF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409223	25910236	DF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409223	25910236	GA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409223	25910236	GA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409223	25910236	GA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409223	25910236	GA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409223	25910236	JB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409223	25910236	JB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409223	25910236	JB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409223	25910236	MM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409223	25910236	MM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409223	25910236	MM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409223	25910236	MS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409223	25910236	NH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409223	25910236	NH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409223	25910236	NH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409223	25910236	OB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409223	25910236	OB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409223	25910236	OB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409223	25910236	SD	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409223	25910236	WH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409223	25910236	WH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409223	25910236	WH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3812784	24179556	IO	2	participated in the design of the study and included patients of her daily practice	participated in the design of the study and included patients of her daily practice	Conceived and designed the experiments	Methodology	YES
3812784	24179556	LAG	2	wrote the manuscript, conceived the study and participated in its design and coordination	wrote the manuscript, conceived the study and participated in its design and coordination	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
3812784	24179556	MM	2	participated in the design of the study and included patients of his daily practice	participated in the design of the study and included patients of his daily practice	Conceived and designed the experiments	Methodology	YES
3812784	24179556	MR	2	included patients of his daily practice and examined x-ray	included patients of his daily practice and examined x-ray	Performed the experiments	Investigation	YES
3812784	24179556	ZT	2	participated in the design of the study, performed the statistical analysis and included patients of his daily practice	participated in the design of the study, performed the statistical analysis and included patients of his daily practice	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
3600668	23446051	JMP	2	contributed to the study design and manuscript review and revision	contributed to the study design and manuscript review and revision	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
3600668	23446051	KMT	2	performed the study and data interpretation	performed the study and data interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3600668	23446051	LWL	2	participated in the manuscript review and revision	participated in the manuscript review and revision	Wrote the paper	Writing - Review & Editing	YES
3600668	23446051	MMM	2	designed the optical techniques utilized and contributed to the primary development of the hbe model and study design	designed the optical techniques utilized and contributed to the primary development of the hbe model and study design	Conceived and designed the experiments|Performed the experiments	Methodology	YES
3600668	23446051	SB	2	contributed to the study design and performed the study and analyzed the data	contributed to the study design and performed the study and analyzed the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Methodology|Resources	YES
3600668	23446051	TEC	2	contributed to the primary study design and interpretation and presentation of data and primarily wrote the manuscript	contributed to the primary study design and interpretation and presentation of data and primarily wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Original Draft	YES
5623722	29021798	AT	2	contributed in the bioinformatics works, helped ds in the final round of genotypic data analysis and corrected the manuscript	contributed in the bioinformatics works, helped ds in the final round of genotypic data analysis and corrected the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Review & Editing	YES
5623722	29021798	All the authors	2	were involved in the planning and execution of the work	were involved in the planning and execution of the work	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5623722	29021798	C-OO	2	helped ds in the phenotypic evaluation and corrected the manuscript	helped ds in the phenotypic evaluation and corrected the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5623722	29021798	DS	2	majorly conducted all the experiments, lab works, analyzed data in final round, and prepared the manuscript draft	majorly conducted all the experiments, lab works, analyzed data in final round, and prepared the manuscript draft	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5623722	29021798	ER	2	helped ds in the phenotypic evaluation and corrected the manuscript	helped ds in the phenotypic evaluation and corrected the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5623722	29021798	SA	2	helped ds in the generation of mapping populations and lab works, and majorly analyzed the genotypic data and qtl mapping in the first round and corrected the first draft of the manuscript	helped ds in the generation of mapping populations and lab works, and majorly analyzed the genotypic data and qtl mapping in the first round and corrected the first draft of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
1762436	17183673	AM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Provided grant funding	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762436	17183673	AM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Provided grant funding	Analyzed the data	Analyzed the data	Formal analysis	YES
1762436	17183673	AM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Provided grant funding	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762436	17183673	AM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Provided grant funding	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762436	17183673	AM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Provided grant funding	Provided grant funding	-	Funding acquisition	YES
1762436	17183673	BD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762436	17183673	BD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762436	17183673	BD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762436	17183673	BD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762436	17183673	DR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762436	17183673	DR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762436	17183673	DR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762436	17183673	FG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Provided grant funding	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762436	17183673	FG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Provided grant funding	Analyzed the data	Analyzed the data	Formal analysis	YES
1762436	17183673	FG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Provided grant funding	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762436	17183673	FG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Provided grant funding	Provided grant funding	-	Funding acquisition	YES
1762436	17183673	MC	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762436	17183673	SB	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762436	17183673	SB	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762436	17183673	SP	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762436	17183673	SP	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5978661	29171179	All authors	2	contributed to writing and reviewing the science	contributed to writing and reviewing the science	Wrote the paper	Writing - Review & Editing	YES
5978661	29171179	EA	2	developed the initial concept and idea	developed the initial concept and idea	Conceived and designed the experiments	Conceptualization	YES
5978661	29171179	EM	2	carried out the simulations, calibration and statistical analysis	carried out the simulations, calibration and statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5978661	29171179	LM	2	developed the initial concept and idea	developed the initial concept and idea	Conceived and designed the experiments	Conceptualization	YES
5978661	29171179	ML	2	developed the initial concept and idea|developed and wrote the first version of the simulation models|carried out the simulations, calibration and statistical analysis|drafted the first version of the manuscript	developed the initial concept and idea	Conceived and designed the experiments	Conceptualization	YES
5978661	29171179	ML	2	developed the initial concept and idea|developed and wrote the first version of the simulation models|carried out the simulations, calibration and statistical analysis|drafted the first version of the manuscript	developed and wrote the first version of the simulation models	Performed the experiments|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5978661	29171179	ML	2	developed the initial concept and idea|developed and wrote the first version of the simulation models|carried out the simulations, calibration and statistical analysis|drafted the first version of the manuscript	carried out the simulations, calibration and statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5978661	29171179	ML	2	developed the initial concept and idea|developed and wrote the first version of the simulation models|carried out the simulations, calibration and statistical analysis|drafted the first version of the manuscript	drafted the first version of the manuscript	Wrote the paper	Writing - Original Draft	YES
5978661	29171179	NYH	2	assisted in study conceptualization provided expertise regarding viral load monitoring	assisted in study conceptualization provided expertise regarding viral load monitoring	Conceived and designed the experiments	Conceptualization|Supervision	YES
5978661	29171179	TG	2	carried out the simulations, calibration and statistical analysis	carried out the simulations, calibration and statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5437562	28521758	CMS	1	Data management, analysis and interpretation|Manuscript writing	Data management, analysis and interpretation	Analyzed the data	Data curation|Formal analysis	YES
5437562	28521758	CMS	1	Data management, analysis and interpretation|Manuscript writing	Manuscript writing	Wrote the paper	Writing - Original Draft	YES
5437562	28521758	DJG	1	Data management, analysis and interpretation	Data management, analysis and interpretation	Analyzed the data	Data curation|Formal analysis	YES
5437562	28521758	JED	1	Data management, analysis and interpretation	Data management, analysis and interpretation	Analyzed the data	Data curation|Formal analysis	YES
5437562	28521758	JFT	1	Data management, analysis and interpretation	Data management, analysis and interpretation	Analyzed the data	Data curation|Formal analysis	YES
5437562	28521758	MS	1	Data management, analysis and interpretation	Data management, analysis and interpretation	Analyzed the data	Data curation|Formal analysis	YES
5437562	28521758	RDS	1	Data management, analysis and interpretation	Data management, analysis and interpretation	Analyzed the data	Data curation|Formal analysis	YES
4409290	25910276	BCP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409290	25910276	BCP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409290	25910276	BCP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409290	25910276	HN	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409290	25910276	JH	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409290	25910276	JH	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409290	25910276	JH	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409290	25910276	JR	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409290	25910276	JR	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409290	25910276	JR	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409290	25910276	WL	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4409290	25910276	WL	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5623726	29021807	HB	2	performed most of the experiments and drafted the manuscript	performed most of the experiments and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5623726	29021807	PZ	2	coordinated and designed the study and revised the article	coordinated and designed the study and revised the article	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Review & Editing	YES
5623726	29021807	WF	2	conducted part of yeast two-hybrid assay	conducted part of yeast two-hybrid assay	Performed the experiments	Investigation	YES
3610303	23497537	CF	2	calculated the estimation of the dosimetry	calculated the estimation of the dosimetry	Analyzed the data	Formal analysis	YES
3610303	23497537	CWH	2	participated in the design of the study|drafted the manuscript	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
3610303	23497537	CWH	2	participated in the design of the study|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
3610303	23497537	JAE	2	participated in the design of the study, carried out the experimental studies and analysed the data	participated in the design of the study, carried out the experimental studies and analysed the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
3610303	23497537	JTG	2	participated in the design of the study	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
3610303	23497537	JTR	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
3610303	23497537	LF	2	carried out the tracer preparation	carried out the tracer preparation	Performed the experiments	Investigation	YES
3610303	23497537	MR	2	participated both in designing the study and in analysing the data	participated both in designing the study and in analysing the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
3610303	23497537	RHP	2	carried out the experimental studies and participated in the analysis of data|drafted the manuscript	carried out the experimental studies and participated in the analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3610303	23497537	RHP	2	carried out the experimental studies and participated in the analysis of data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
3610303	23497537	RM	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
1762437	17205139	EM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762437	17205139	EM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762437	17205139	EM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1762437	17205139	EM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762437	17205139	JA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762437	17205139	JA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762437	17205139	JA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762437	17205139	LA	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762437	17205139	LA	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762437	17205139	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762437	17205139	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762437	17205139	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762437	17205139	MM	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762437	17205139	MM	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1762437	17205139	PC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1762437	17205139	PC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1762437	17205139	PC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1762437	17205139	PC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1762437	17205139	PS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1762437	17205139	PS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5978662	29485748	KT	2	researched, analysed data and drafted this commentary	researched, analysed data and drafted this commentary	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4409291	25909987	CM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409291	25909987	CM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4409291	25909987	CM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409291	25909987	K-UE	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4409291	25909987	K-UE	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409291	25909987	MVBG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409291	25909987	MVBG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4409291	25909987	MVBG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409291	25909987	NS	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409291	25909987	NS	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409291	25909987	PL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4409291	25909987	PL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409291	25909987	WA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409291	25909987	WA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409291	25909987	WA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409291	25909987	WA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409291	25909987	WA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5437716	28525982	All authors	2	have written and approved the final version of the manuscript	have written and approved the final version of the manuscript	Wrote the paper	Writing - Original Draft	YES
5437716	28525982	RI	2	contributed to the conception and design of this study|were involved in the analysis and interpretation of the data	contributed to the conception and design of this study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5437716	28525982	RI	2	contributed to the conception and design of this study|were involved in the analysis and interpretation of the data	were involved in the analysis and interpretation of the data	Analyzed the data	Formal analysis	YES
5437716	28525982	SRH	2	contributed to the conception and design of this study|acquired the data|were involved in the analysis and interpretation of the data	contributed to the conception and design of this study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5437716	28525982	SRH	2	contributed to the conception and design of this study|acquired the data|were involved in the analysis and interpretation of the data	acquired the data	Performed the experiments	Investigation	YES
5437716	28525982	SRH	2	contributed to the conception and design of this study|acquired the data|were involved in the analysis and interpretation of the data	were involved in the analysis and interpretation of the data	Analyzed the data	Formal analysis	YES
5437716	28525982	TT	2	acquired the data|were involved in the analysis and interpretation of the data	acquired the data	Performed the experiments	Investigation	YES
5437716	28525982	TT	2	acquired the data|were involved in the analysis and interpretation of the data	were involved in the analysis and interpretation of the data	Analyzed the data	Formal analysis	YES
3614476	23414629	CA	2	contributed to the intellectual content and critical review of the manuscript	contributed to the intellectual content and critical review of the manuscript	Wrote the paper	Writing - Review & Editing	YES
3614476	23414629	CBM	2	contributed to the intellectual content and critical review of the manuscript	contributed to the intellectual content and critical review of the manuscript	Wrote the paper	Writing - Review & Editing	YES
3614476	23414629	CR	2	contributed to the intellectual content and critical review of the manuscript	contributed to the intellectual content and critical review of the manuscript	Wrote the paper	Writing - Review & Editing	YES
3614476	23414629	EG	2	contributed significantly to the patient study and reviewed and approved the final content of the manuscript	contributed significantly to the patient study and reviewed and approved the final content of the manuscript	Wrote the paper	Writing - Review & Editing	YES
3614476	23414629	FKB	2	participated to the study design and coordination, and helped draft the manuscript	participated to the study design and coordination, and helped draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft	YES
3614476	23414629	FS	2	interpreted the results, gave a critical review of the work, and contributed to the enhancement of the manuscript	interpreted the results, gave a critical review of the work, and contributed to the enhancement of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
3614476	23414629	JB	2	interpreted the results, gave a critical review of the work, and contributed to the enhancement of the manuscript	interpreted the results, gave a critical review of the work, and contributed to the enhancement of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
3614476	23414629	LF	2	contributed to the intellectual content and critical review of the manuscript	contributed to the intellectual content and critical review of the manuscript	Wrote the paper	Writing - Review & Editing	YES
3614476	23414629	TC	2	performed the data acquisition, analysis, and interpretation|is the main author of the manuscript	performed the data acquisition, analysis, and interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3614476	23414629	TC	2	performed the data acquisition, analysis, and interpretation|is the main author of the manuscript	is the main author of the manuscript	Wrote the paper	Writing - Original Draft	YES
3614476	23414629	TE	2	contributed significantly to the patient study and reviewed and approved the final content of the manuscript	contributed significantly to the patient study and reviewed and approved the final content of the manuscript	Wrote the paper	Writing - Review & Editing	YES
3866697	24358067	C. Li	7	statistical analysis and interpretation, critical revision/drafting of the manuscript, final approval to submit. M	statistical analysis and interpretation, critical revision/drafting of the manuscript, final approval to submit. M	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
3866697	24358067	L. Kellner	7	conduct of study, analysis and interpretation of data, critical revision/drafting of the manuscript, final approval to submit	conduct of study, analysis and interpretation of data, critical revision/drafting of the manuscript, final approval to submit	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
3866697	24358067	N. Essex	7	analysis and interpretation of data, critical revision/drafting of the manuscript, final approval to submit	analysis and interpretation of data, critical revision/drafting of the manuscript, final approval to submit	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5623909	29021808	CC	2	analyzed the data and wrote the manuscript|conceived and supervised the study	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5623909	29021808	CC	2	analyzed the data and wrote the manuscript|conceived and supervised the study	conceived and supervised the study	Conceived and designed the experiments	Conceptualization|Supervision	YES
5623909	29021808	DL	2	performed the study with the	performed the study with the	Performed the experiments	Investigation	YES
5623909	29021808	GZ	2	assisted with the performed the study with the	assisted with the performed the study with the	Performed the experiments	Investigation	YES
5623909	29021808	HT	2	assisted with the performed the study with the|analyzed the data and wrote the manuscript|conceived and supervised the study	assisted with the performed the study with the	Performed the experiments	Investigation	YES
5623909	29021808	HT	2	assisted with the performed the study with the|analyzed the data and wrote the manuscript|conceived and supervised the study	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5623909	29021808	HT	2	assisted with the performed the study with the|analyzed the data and wrote the manuscript|conceived and supervised the study	conceived and supervised the study	Conceived and designed the experiments	Conceptualization|Supervision	YES
5623909	29021808	YX	2	performed the study with the|analyzed the data and wrote the manuscript	performed the study with the	Performed the experiments	Investigation	YES
5623909	29021808	YX	2	performed the study with the|analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
1764032	17206277	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1764032	17206277	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1764032	17206277	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1764032	17206277	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1764032	17206277	BN	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Designed and analyzed the computational model	Performed the experiments	Performed the experiments	Investigation	YES
1764032	17206277	BN	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Designed and analyzed the computational model	Analyzed the data	Analyzed the data	Formal analysis	YES
1764032	17206277	BN	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Designed and analyzed the computational model	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1764032	17206277	BN	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Designed and analyzed the computational model	Designed and analyzed the computational model	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Methodology	YES
1764032	17206277	DI	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Designed and analyzed the computational model	Performed the experiments	Performed the experiments	Investigation	YES
1764032	17206277	DI	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Designed and analyzed the computational model	Analyzed the data	Analyzed the data	Formal analysis	YES
1764032	17206277	DI	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Designed and analyzed the computational model	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1764032	17206277	DI	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Designed and analyzed the computational model	Designed and analyzed the computational model	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Methodology	YES
1764032	17206277	FW	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Designed and analyzed the computational model	Performed the experiments	Performed the experiments	Investigation	YES
1764032	17206277	FW	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Designed and analyzed the computational model	Analyzed the data	Analyzed the data	Formal analysis	YES
1764032	17206277	FW	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Designed and analyzed the computational model	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1764032	17206277	FW	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Designed and analyzed the computational model	Designed and analyzed the computational model	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Methodology	YES
1764032	17206277	GS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Designed and analyzed the computational model	Performed the experiments	Performed the experiments	Investigation	YES
1764032	17206277	GS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Designed and analyzed the computational model	Analyzed the data	Analyzed the data	Formal analysis	YES
1764032	17206277	GS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Designed and analyzed the computational model	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1764032	17206277	GS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Designed and analyzed the computational model	Designed and analyzed the computational model	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Methodology	YES
1764032	17206277	HT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1764032	17206277	HT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1764032	17206277	HT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1764032	17206277	HT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1764032	17206277	JM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1764032	17206277	JM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1764032	17206277	JM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1764032	17206277	JP	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1764032	17206277	JP	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1764032	17206277	KG	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1764032	17206277	KG	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1764032	17206277	MW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1764032	17206277	MW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1764032	17206277	MW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1764032	17206277	MW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1764032	17206277	QN	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Designed and analyzed the computational model	Performed the experiments	Performed the experiments	Investigation	YES
1764032	17206277	QN	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Designed and analyzed the computational model	Analyzed the data	Analyzed the data	Formal analysis	YES
1764032	17206277	QN	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Designed and analyzed the computational model	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1764032	17206277	QN	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Designed and analyzed the computational model	Designed and analyzed the computational model	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Methodology	YES
1764032	17206277	TL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1764032	17206277	TL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1764032	17206277	TL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1764032	17206277	TL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5978663	29130605	All authors	2	contributed equally to this work|discussed the results and implications, and commented on the manuscript at all stages	contributed equally to this work	-	-	NO
5978663	29130605	All authors	2	contributed equally to this work|discussed the results and implications, and commented on the manuscript at all stages	discussed the results and implications, and commented on the manuscript at all stages	-	-	NO
5978663	29130605	BK	2	led the implementation of all aspects of the work on routine viral load testing presented here	led the implementation of all aspects of the work on routine viral load testing presented here	Performed the experiments	Investigation	YES
5978663	29130605	TT	2	provided operational oversight and implementation support|wrote the main paper	provided operational oversight and implementation support	Performed the experiments	Investigation|Supervision	YES
5978663	29130605	TT	2	provided operational oversight and implementation support|wrote the main paper	wrote the main paper	Wrote the paper	Writing - Original Draft	YES
5978663	29130605	WM	2	provided technical oversight and implementation support	provided technical oversight and implementation support	Performed the experiments	Investigation|Supervision	YES
4409293	25909911	AA	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4409293	25909911	AA	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409293	25909911	CG	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4409293	25909911	CG	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409293	25909911	D. Fedorova	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4409293	25909911	D. Fedorova	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409293	25909911	D. Frendewey	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409293	25909911	D. Frendewey	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409293	25909911	D. Frendewey	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409293	25909911	DMV	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409293	25909911	DMV	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409293	25909911	DMV	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409293	25909911	DW	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4409293	25909911	DW	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409293	25909911	GD	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4409293	25909911	GD	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409293	25909911	GDY	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409293	25909911	GG	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409293	25909911	GG	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409293	25909911	GG	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409293	25909911	J. Rinn	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409293	25909911	J. Rojas	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4409293	25909911	J. Rojas	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409293	25909911	JP	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4409293	25909911	JP	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409293	25909911	JQ	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4409293	25909911	JQ	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409293	25909911	K-MVL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409293	25909911	K-MVL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409293	25909911	K-MVL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409293	25909911	LM	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4409293	25909911	LM	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409293	25909911	MH	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4409293	25909911	MH	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409293	25909911	WA	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409293	25909911	WA	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409293	25909911	WTP	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4409293	25909911	WTP	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
3614539	23521849	AJ	2	designed the study and interpreted all images|revised the manuscript	designed the study and interpreted all images	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology|Visualization	YES
3614539	23521849	AJ	2	designed the study and interpreted all images|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
3614539	23521849	BJ	2	helped with the design of the study, assessed the image quality, and revised the manuscript	helped with the design of the study, assessed the image quality, and revised the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Methodology|Validation|Visualization|Writing - Review & Editing	YES
3614539	23521849	CO	2	helped with the design of the study, assessed the image quality, and revised the manuscript	helped with the design of the study, assessed the image quality, and revised the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Methodology|Validation|Visualization|Writing - Review & Editing	YES
3614539	23521849	DM	2	helped with the design of the study, provided insights into physics, and revised the manuscript	helped with the design of the study, provided insights into physics, and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
3614539	23521849	ET	2	designed the study and interpreted all images|drafted the manuscript	designed the study and interpreted all images	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology|Visualization	YES
3614539	23521849	ET	2	designed the study and interpreted all images|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
3614539	23521849	GH	2	helped with the design of the study, assessed the image quality, and revised the manuscript	helped with the design of the study, assessed the image quality, and revised the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Methodology|Validation|Visualization|Writing - Review & Editing	YES
3614539	23521849	KN	2	helped with the design of the study and organization/setup of all images	helped with the design of the study and organization/setup of all images	Conceived and designed the experiments|Analyzed the data	Methodology|Project administration|Visualization	YES
3614539	23521849	LE	2	helped in the design of the study and revised the manuscript	helped in the design of the study and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
3614539	23521849	LJ	2	helped with the design of the study, assessed the image quality, and revised the manuscript	helped with the design of the study, assessed the image quality, and revised the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Methodology|Validation|Visualization|Writing - Review & Editing	YES
3614539	23521849	LLJ	2	helped with the design of the study, assessed the image quality, and revised the manuscript	helped with the design of the study, assessed the image quality, and revised the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Methodology|Validation|Visualization|Writing - Review & Editing	YES
3614539	23521849	ML	2	designed the study and interpreted all images|revised the manuscript	designed the study and interpreted all images	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology|Visualization	YES
3614539	23521849	ML	2	designed the study and interpreted all images|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
3614539	23521849	MSR	2	helped with the design of the study, assessed the image quality, and revised the manuscript	helped with the design of the study, assessed the image quality, and revised the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Methodology|Validation|Visualization|Writing - Review & Editing	YES
3614539	23521849	OG	2	helped with the design of the study, performed the statistical analysis, and contributed to the writing of the manuscript	helped with the design of the study, performed the statistical analysis, and contributed to the writing of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3614539	23521849	PW	2	helped in the design of the study and revised the manuscript	helped in the design of the study and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5438547	28525990	ASA	2	assisted with all analyses	assisted with all analyses	Analyzed the data	Formal analysis	YES
5438547	28525990	All authors	2	contributed to the writing and editing of the final manuscript	contributed to the writing and editing of the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5438547	28525990	CG	2	conceived the study|performed the pop-starr assay and all related analysis|designed the sequencing study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5438547	28525990	CG	2	conceived the study|performed the pop-starr assay and all related analysis|designed the sequencing study	performed the pop-starr assay and all related analysis	Performed the experiments	Investigation	YES
5438547	28525990	CG	2	conceived the study|performed the pop-starr assay and all related analysis|designed the sequencing study	designed the sequencing study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5438547	28525990	DMS	2	called the variants in the initial sequencing	called the variants in the initial sequencing	Performed the experiments	Investigation	YES
5438547	28525990	ICM	2	performed the allele-specific binding analysis	performed the allele-specific binding analysis	Performed the experiments	Investigation	YES
5438547	28525990	MN	2	called the variants in the initial sequencing	called the variants in the initial sequencing	Performed the experiments	Investigation	YES
5438547	28525990	TER	2	conceived the study|designed the sequencing study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5438547	28525990	TER	2	conceived the study|designed the sequencing study	designed the sequencing study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5438547	28525990	WLL	2	designed the sequencing study	designed the sequencing study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
1764033	17206281	HK	1	Was responsible for database configuration and manipulation helping in better control of results for the manuscript	Was responsible for database configuration and manipulation helping in better control of results for the manuscript	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
1764033	17206281	JW	1	Participated in generation of results for the manuscript	Participated in generation of results for the manuscript	-	-	NO
1764033	17206281	MK	1	Recruited subjects and coordinated clinical analysis and data base entry for the study	Recruited subjects and coordinated clinical analysis and data base entry for the study	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Formal analysis|Investigation|Project administration|Software	YES
1764033	17206281	PJ	1	Participated in analysis of results for the manuscript	Participated in analysis of results for the manuscript	Analyzed the data	Formal analysis	YES
1764033	17206281	RA	1	Helped in the design of the study, facilitating recruitment and providing clinical expertise in characterizing subjects for the manuscript	Helped in the design of the study, facilitating recruitment and providing clinical expertise in characterizing subjects for the manuscript	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
1764033	17206281	SG	1	Principal investigator and corresponding author, was instrumental in study design, analysis guidance, interpretation and writing the manuscript|Actively participated in study design, experimental execution, analysis of generated data and writing the manuscript	Principal investigator and corresponding author, was instrumental in study design, analysis guidance, interpretation and writing the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Funding acquisition|Methodology|Supervision|Writing - Original Draft	YES
1764033	17206281	SG	1	Principal investigator and corresponding author, was instrumental in study design, analysis guidance, interpretation and writing the manuscript|Actively participated in study design, experimental execution, analysis of generated data and writing the manuscript	Actively participated in study design, experimental execution, analysis of generated data and writing the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
1764033	17206281	SJ	1	Participated in generation of results for the manuscript	Participated in generation of results for the manuscript	-	-	NO
5623933	29021805	All authors	2	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5623933	29021805	CW	2	contributed to data collection and interpretation	contributed to data collection and interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5623933	29021805	FL	2	contributed to data collection and interpretation	contributed to data collection and interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5623933	29021805	XC	2	wrote the manuscript and executed the technical assays and statistical analysis|designed the experiment and edited the manuscript text	wrote the manuscript and executed the technical assays and statistical analysis	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5623933	29021805	XC	2	wrote the manuscript and executed the technical assays and statistical analysis|designed the experiment and edited the manuscript text	designed the experiment and edited the manuscript text	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5623933	29021805	YL	2	wrote the manuscript and executed the technical assays and statistical analysis	wrote the manuscript and executed the technical assays and statistical analysis	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5623933	29021805	YX	2	designed the experiment and edited the manuscript text	designed the experiment and edited the manuscript text	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5623933	29021805	ZD	2	contributed to data collection and interpretation	contributed to data collection and interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5623933	29021805	ZH	2	contributed to data collection and interpretation	contributed to data collection and interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5978664	29485739	All authors	PLoS52	reviewed and approved the final version	reviewed and approved the final version	-	-	NO
5978664	29485739	ET	PLoS52	had responsibility for the overall study design and management|wrote the paper	had responsibility for the overall study design and management	Conceived and designed the experiments	Methodology	YES
5978664	29485739	ET	PLoS52	had responsibility for the overall study design and management|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5978664	29485739	LC	PLoS52	had responsibility for the overall study design and management|had responsibility for conceptualizing the paper|conducted the analyses for the paper|wrote the paper	had responsibility for the overall study design and management	Conceived and designed the experiments	Methodology	YES
5978664	29485739	LC	PLoS52	had responsibility for the overall study design and management|had responsibility for conceptualizing the paper|conducted the analyses for the paper|wrote the paper	had responsibility for conceptualizing the paper	Conceived and designed the experiments	Conceptualization	YES
5978664	29485739	LC	PLoS52	had responsibility for the overall study design and management|had responsibility for conceptualizing the paper|conducted the analyses for the paper|wrote the paper	conducted the analyses for the paper	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5978664	29485739	LC	PLoS52	had responsibility for the overall study design and management|had responsibility for conceptualizing the paper|conducted the analyses for the paper|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5978664	29485739	LS	PLoS52	had responsibility for conceptualizing the paper|wrote the paper	had responsibility for conceptualizing the paper	Conceived and designed the experiments	Conceptualization	YES
5978664	29485739	LS	PLoS52	had responsibility for conceptualizing the paper|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5978664	29485739	MO	PLoS52	had responsibility for conceptualizing the paper|conducted the analyses for the paper	had responsibility for conceptualizing the paper	Conceived and designed the experiments	Conceptualization	YES
5978664	29485739	MO	PLoS52	had responsibility for conceptualizing the paper|conducted the analyses for the paper	conducted the analyses for the paper	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5978664	29485739	MP	PLoS52	had responsibility for the overall study design and management|had responsibility for conceptualizing the paper|conducted the analyses for the paper|wrote the paper	had responsibility for the overall study design and management	Conceived and designed the experiments	Methodology	YES
5978664	29485739	MP	PLoS52	had responsibility for the overall study design and management|had responsibility for conceptualizing the paper|conducted the analyses for the paper|wrote the paper	had responsibility for conceptualizing the paper	Conceived and designed the experiments	Conceptualization	YES
5978664	29485739	MP	PLoS52	had responsibility for the overall study design and management|had responsibility for conceptualizing the paper|conducted the analyses for the paper|wrote the paper	conducted the analyses for the paper	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5978664	29485739	MP	PLoS52	had responsibility for the overall study design and management|had responsibility for conceptualizing the paper|conducted the analyses for the paper|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5978664	29485739	SM	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3618317	23497589	All authors	2	edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
3618317	23497589	CT	2	data and drafted the manuscript	data and drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
3618317	23497589	JT	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
3618317	23497589	LH	2	did the hplc quality control	did the hplc quality control	Performed the experiments	Investigation|Validation	YES
3618317	23497589	MHS	2	designed the study|did hplc analyses and supervised all other analyses	designed the study	Conceived and designed the experiments	Methodology	YES
3618317	23497589	MHS	2	designed the study|did hplc analyses and supervised all other analyses	did hplc analyses and supervised all other analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Supervision	YES
3618317	23497589	OS	2	designed the study|prepared tracers	designed the study	Conceived and designed the experiments	Methodology	YES
3618317	23497589	OS	2	designed the study|prepared tracers	prepared tracers	-	-	NO
3618317	23497589	SF	2	prepared tracers	prepared tracers	-	-	NO
3618317	23497589	TJG	2	scanned the subjects	scanned the subjects	-	-	NO
3618317	23497589	TV	2	made statistical analyses	made statistical analyses	Analyzed the data	Formal analysis	YES
4409294	25910003	JWK	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409294	25910003	MKY	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409294	25910003	MKY	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409294	25910003	MKY	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409294	25910003	WRW	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409294	25910003	YKH	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409294	25910003	YKH	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1764034	17206274	AS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1764034	17206274	AT	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1764034	17206274	AT	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1764034	17206274	BP	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1764034	17206274	BP	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1764034	17206274	CB	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1764034	17206274	CR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1764034	17206274	CR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1764034	17206274	CR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1764034	17206274	CR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1764034	17206274	CS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1764034	17206274	EB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1764034	17206274	FA	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1764034	17206274	JL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1764034	17206274	JL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1764034	17206274	JP	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1764034	17206274	JT	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1764034	17206274	JT	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1764034	17206274	JT	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1764034	17206274	LM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1764034	17206274	ME	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1764034	17206274	MG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1764034	17206274	NN	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1764034	17206274	NN	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1764034	17206274	NN	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1764034	17206274	OM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1764034	17206274	OM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1764034	17206274	OM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1764034	17206274	OM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1764034	17206274	RD	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1764034	17206274	RD	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1764034	17206274	RD	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1764034	17206274	SC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1764034	17206274	TF	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5978666	29485728	HIV	2	drafted the first draft	drafted the first draft	Wrote the paper	Writing - Original Draft	YES
5978666	29485728	SDGs	2	contributed to the writing of the manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
3621254	23557183	EE	2	participated in planning and performing the in vivo studies	participated in planning and performing the in vivo studies	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3621254	23557183	JT	2	contributed to the study design and analyses of data as well as writing of the manuscript	contributed to the study design and analyses of data as well as writing of the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Original Draft	YES
3621254	23557183	RN	2	contributed to the study design and analyses of data as well as writing of the manuscript	contributed to the study design and analyses of data as well as writing of the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Original Draft	YES
3621254	23557183	SEE	2	designed and performed the in vivo studies, evaluated the immunohistochemistry, performed the statistical analyses, and wrote the manuscript	designed and performed the in vivo studies, evaluated the immunohistochemistry, performed the statistical analyses, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
3621254	23557183	SL	2	developed and performed the radiolabeling, and contributed to data interpretation and manuscript writing	developed and performed the radiolabeling, and contributed to data interpretation and manuscript writing	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3621254	23557183	TB	2	participated in planning the experiment, performed the dosimetric calculations, and contributed to data interpretation and manuscript writing	participated in planning the experiment, performed the dosimetric calculations, and contributed to data interpretation and manuscript writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5440902	28532419	AF	PLoS52	conceived and designed the experiments|collected the samples|conducted analysis|critically revised the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5440902	28532419	AF	PLoS52	conceived and designed the experiments|collected the samples|conducted analysis|critically revised the manuscript	collected the samples	Performed the experiments	Investigation	YES
5440902	28532419	AF	PLoS52	conceived and designed the experiments|collected the samples|conducted analysis|critically revised the manuscript	conducted analysis	Performed the experiments	Investigation	YES
5440902	28532419	AF	PLoS52	conceived and designed the experiments|collected the samples|conducted analysis|critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5440902	28532419	AM	PLoS52	collected the samples	collected the samples	Performed the experiments	Investigation	YES
5440902	28532419	FCB	PLoS52	conceived and designed the experiments|critically revised the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5440902	28532419	FCB	PLoS52	conceived and designed the experiments|critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5440902	28532419	LK	PLoS52	conducted analysis	conducted analysis	Performed the experiments	Investigation	YES
5440902	28532419	NVH	PLoS52	conceived and designed the experiments|collected the samples|conducted analysis|prepared the first draft|critically revised the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5440902	28532419	NVH	PLoS52	conceived and designed the experiments|collected the samples|conducted analysis|prepared the first draft|critically revised the manuscript	collected the samples	Performed the experiments	Investigation	YES
5440902	28532419	NVH	PLoS52	conceived and designed the experiments|collected the samples|conducted analysis|prepared the first draft|critically revised the manuscript	conducted analysis	Performed the experiments	Investigation	YES
5440902	28532419	NVH	PLoS52	conceived and designed the experiments|collected the samples|conducted analysis|prepared the first draft|critically revised the manuscript	prepared the first draft	Wrote the paper	Writing - Original Draft	YES
5440902	28532419	NVH	PLoS52	conceived and designed the experiments|collected the samples|conducted analysis|prepared the first draft|critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5440902	28532419	PJM	PLoS52	collected the samples	collected the samples	Performed the experiments	Investigation	YES
5440902	28532419	PPT	PLoS52	conducted analysis|critically revised the manuscript	conducted analysis	Performed the experiments	Investigation	YES
5440902	28532419	PPT	PLoS52	conducted analysis|critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5440902	28532419	RJH	PLoS52	conceived and designed the experiments|critically revised the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5440902	28532419	RJH	PLoS52	conceived and designed the experiments|critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5623940	29021804	JY	PLoS52	performed the experiments|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5623940	29021804	JY	PLoS52	performed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5623940	29021804	JhY	PLoS52	edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5623940	29021804	LN	PLoS52	performed the experiments|performed data analysis|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5623940	29021804	LN	PLoS52	performed the experiments|performed data analysis|wrote the manuscript	performed data analysis	Analyzed the data	Formal analysis	YES
5623940	29021804	LN	PLoS52	performed the experiments|performed data analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5623940	29021804	MD	PLoS52	edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5623940	29021804	MZ	PLoS52	performed data analysis	performed data analysis	Analyzed the data	Formal analysis	YES
5623940	29021804	WL	PLoS52	designed the experiments|performed data analysis|wrote the manuscript|edited the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5623940	29021804	WL	PLoS52	designed the experiments|performed data analysis|wrote the manuscript|edited the manuscript	performed data analysis	Analyzed the data	Formal analysis	YES
5623940	29021804	WL	PLoS52	designed the experiments|performed data analysis|wrote the manuscript|edited the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5623940	29021804	WL	PLoS52	designed the experiments|performed data analysis|wrote the manuscript|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
4409295	25909753	DG	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409295	25909753	DG	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409295	25909753	DG	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409295	25909753	DG	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409295	25909753	YC	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409295	25909753	YC	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409295	25909753	YC	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409295	25909753	YC	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4538580	26339633	Wei-Lian Phan	2	contributed equally to this work	contributed equally to this work	-	-	NO
4538580	26339633	Yu-Tzu Huang	2	contributed equally to this work	contributed equally to this work	-	-	NO
3623622	23557209	AAL	2	proofread the manuscript	proofread the manuscript	-	-	NO
3623622	23557209	ADW	2	participated in the study design, coordination and discussion of findings|proofread the manuscript	participated in the study design, coordination and discussion of findings	Conceived and designed the experiments	Methodology|Project administration	YES
3623622	23557209	ADW	2	participated in the study design, coordination and discussion of findings|proofread the manuscript	proofread the manuscript	-	-	NO
3623622	23557209	HJCB	2	performed the carbon-11 tracer synthesis and animal studies|participated in the study design, coordination and discussion of findings	performed the carbon-11 tracer synthesis and animal studies	Performed the experiments	Investigation	YES
3623622	23557209	HJCB	2	performed the carbon-11 tracer synthesis and animal studies|participated in the study design, coordination and discussion of findings	participated in the study design, coordination and discussion of findings	Conceived and designed the experiments	Methodology|Project administration	YES
3623622	23557209	JAJS	2	participated in the study design, coordination and discussion of findings|proofread the manuscript	participated in the study design, coordination and discussion of findings	Conceived and designed the experiments	Methodology|Project administration	YES
3623622	23557209	JAJS	2	participated in the study design, coordination and discussion of findings|proofread the manuscript	proofread the manuscript	-	-	NO
3623622	23557209	JEL	2	participated in the study design, coordination and discussion of findings|proofread the manuscript	participated in the study design, coordination and discussion of findings	Conceived and designed the experiments	Methodology|Project administration	YES
3623622	23557209	JEL	2	participated in the study design, coordination and discussion of findings|proofread the manuscript	proofread the manuscript	-	-	NO
3623622	23557209	JHDM	2	participated in the study design, coordination and discussion of findings|proofread the manuscript	participated in the study design, coordination and discussion of findings	Conceived and designed the experiments	Methodology|Project administration	YES
3623622	23557209	JHDM	2	participated in the study design, coordination and discussion of findings|proofread the manuscript	proofread the manuscript	-	-	NO
3623622	23557209	MCH	2	participated in the study design, coordination and discussion of findings|proofread the manuscript	participated in the study design, coordination and discussion of findings	Conceived and designed the experiments	Methodology|Project administration	YES
3623622	23557209	MCH	2	participated in the study design, coordination and discussion of findings|proofread the manuscript	proofread the manuscript	-	-	NO
5978668	29485727	All authors	2	contributed equally to drafting the content, editing and reviewing the manuscript for final endorsement	contributed equally to drafting the content, editing and reviewing the manuscript for final endorsement	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
1764035	17206280	EP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1764035	17206280	EP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1764035	17206280	EP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1764035	17206280	FZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1764035	17206280	HW	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1764035	17206280	JL	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Analyzed the data|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1764035	17206280	JL	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Analyzed the data|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1764035	17206280	JL	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Analyzed the data|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1764035	17206280	JL	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Analyzed the data|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1764035	17206280	JM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1764035	17206280	JM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1764035	17206280	JM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1764035	17206280	JS	PLoS5	Contributed reagents/materials/analysis tools|Reviewed the statistical analysis	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1764035	17206280	JS	PLoS5	Contributed reagents/materials/analysis tools|Reviewed the statistical analysis	Reviewed the statistical analysis	Analyzed the data	Formal analysis	YES
4409296	25910196	GDL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409296	25910196	GDL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409296	25910196	GDL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409296	25910196	GDL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409296	25910196	GSZ	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4409296	25910196	GSZ	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409296	25910196	HWC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409296	25910196	HWC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409296	25910196	HWC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409296	25910196	JF	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409296	25910196	JF	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409296	25910196	JP	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409296	25910196	LJW	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409296	25910196	SO	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409296	25910196	SO	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409296	25910196	SO	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3623648	23514539	AAL	2	revised and gave advice for improvement of the manuscript	revised and gave advice for improvement of the manuscript	Wrote the paper	Writing - Review & Editing	YES
3623648	23514539	ADW	2	participated in the study design and discussion and interpretation of findings|revised and gave advice for improvement of the manuscript	participated in the study design and discussion and interpretation of findings	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
3623648	23514539	ADW	2	participated in the study design and discussion and interpretation of findings|revised and gave advice for improvement of the manuscript	revised and gave advice for improvement of the manuscript	Wrote the paper	Writing - Review & Editing	YES
3623648	23514539	AF	2	revised and gave advice for improvement of the manuscript	revised and gave advice for improvement of the manuscript	Wrote the paper	Writing - Review & Editing	YES
3623648	23514539	HJCB	2	performed the carbon-11 tracer synthesis and all animal studies|participated in the study design and discussion and interpretation of findings|drafted the manuscript	performed the carbon-11 tracer synthesis and all animal studies	Performed the experiments	Investigation	YES
3623648	23514539	HJCB	2	performed the carbon-11 tracer synthesis and all animal studies|participated in the study design and discussion and interpretation of findings|drafted the manuscript	participated in the study design and discussion and interpretation of findings	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
3623648	23514539	HJCB	2	performed the carbon-11 tracer synthesis and all animal studies|participated in the study design and discussion and interpretation of findings|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
3623648	23514539	JEL	2	participated in the study design and discussion and interpretation of findings|revised and gave advice for improvement of the manuscript	participated in the study design and discussion and interpretation of findings	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
3623648	23514539	JEL	2	participated in the study design and discussion and interpretation of findings|revised and gave advice for improvement of the manuscript	revised and gave advice for improvement of the manuscript	Wrote the paper	Writing - Review & Editing	YES
3623648	23514539	MCH	2	participated in the study design and discussion and interpretation of findings|revised and gave advice for improvement of the manuscript	participated in the study design and discussion and interpretation of findings	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
3623648	23514539	MCH	2	participated in the study design and discussion and interpretation of findings|revised and gave advice for improvement of the manuscript	revised and gave advice for improvement of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5623950	29021803	AH	2	conceived the project and its components, designed and supervised the study, and revised the manuscript	conceived the project and its components, designed and supervised the study, and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Supervision|Writing - Review & Editing	YES
5623950	29021803	All authors	2	discussed the results, read and approved the manuscript	discussed the results, read and approved the manuscript	-	-	NO
5623950	29021803	GSM	2	contributed to the original concept of the project	contributed to the original concept of the project	Conceived and designed the experiments	Conceptualization	YES
5623950	29021803	RL	2	performed the ground-truthing, analyzed experimental data, and executed phenotypic and statistical data analyses|developed results and wrote the manuscript	performed the ground-truthing, analyzed experimental data, and executed phenotypic and statistical data analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5623950	29021803	RL	2	performed the ground-truthing, analyzed experimental data, and executed phenotypic and statistical data analyses|developed results and wrote the manuscript	developed results and wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5623950	29021803	SK	2	contributed to develop the workflow and write the manuscript	contributed to develop the workflow and write the manuscript	Performed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5440948	28532386	AZ	2	performed the analysis	performed the analysis	Performed the experiments	Investigation	YES
5440948	28532386	DM	2	oversaw the sequencing experiment	oversaw the sequencing experiment	Performed the experiments	Investigation|Supervision	YES
5440948	28532386	EG	2	performed the analysis	performed the analysis	Performed the experiments	Investigation	YES
5440948	28532386	FY	2	conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5440948	28532386	JX	2	conceived the study|performed the analysis	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5440948	28532386	JX	2	conceived the study|performed the analysis	performed the analysis	Performed the experiments	Investigation	YES
5440948	28532386	LBJ	2	conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5440948	28532386	NR	2	performed the analysis|performed the analysis	performed the analysis	Performed the experiments	Investigation	YES
5440948	28532386	NR	2	performed the analysis|performed the analysis	performed the analysis	Performed the experiments	Investigation	YES
5440948	28532386	RAG	2	oversaw the sequencing experiment	oversaw the sequencing experiment	Performed the experiments	Investigation|Supervision	YES
5440948	28532386	SW	2	performed the analysis	performed the analysis	Performed the experiments	Investigation	YES
5440948	28532386	WSW	2	performed the analysis	performed the analysis	Performed the experiments	Investigation	YES
5690371	29546097	LL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5690371	29546097	LL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials	Contributed reagents/materials	Contributed reagents/materials/analysis tools	Resources	YES
5690371	29546097	LX	PLoS5	Conceived and designed the experiments|Performed the experiments and analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5690371	29546097	LX	PLoS5	Conceived and designed the experiments|Performed the experiments and analyzed the data|Wrote the paper	Performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5690371	29546097	LX	PLoS5	Conceived and designed the experiments|Performed the experiments and analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409297	25909634	DF	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4409297	25909634	DF	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4409297	25909634	DF	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409297	25909634	XJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409297	25909634	XJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409297	25909634	XJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409297	25909634	XJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409297	25909634	XJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409297	25909634	XM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409297	25909634	XM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409297	25909634	XM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409297	25909634	XM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409297	25909634	XM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409297	25909634	XW	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4409297	25909634	XW	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4409297	25909634	XW	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
3626673	23557246	CD	2	designed and carried out the experimental studies and wrote the manuscript	designed and carried out the experimental studies and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
3626673	23557246	FDV	2	participated in the design of the study and helped to draft the manuscript	participated in the design of the study and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3626673	23557246	JH	2	participated in the design of protein purification	participated in the design of protein purification	Conceived and designed the experiments|Performed the experiments	Investigation	YES
3626673	23557246	LM	2	contributed to the carrying out of experimental studies and to the revision of the manuscript	contributed to the carrying out of experimental studies and to the revision of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
3626673	23557246	SN	2	contributed to the carrying out of experimental studies and to the revision of the manuscript	contributed to the carrying out of experimental studies and to the revision of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
3626673	23557246	SS	2	contributed to the conception and design of the study and critically contributed to and revised the manuscript	contributed to the conception and design of the study and critically contributed to and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
1764036	17206278	DP	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1764036	17206278	DP	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1764036	17206278	DP	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1764036	17206278	NB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1764036	17206278	NB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1764036	17206278	NB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1764036	17206278	PC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1764036	17206278	PC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1764036	17206278	PC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1764036	17206278	PC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1764036	17206278	PC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5623951	29021799	GH-S	2	conceived and designed the proteomics experiments|performed the mass spectrometry experiments and data analysis|wrote the manuscript	conceived and designed the proteomics experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5623951	29021799	GH-S	2	conceived and designed the proteomics experiments|performed the mass spectrometry experiments and data analysis|wrote the manuscript	performed the mass spectrometry experiments and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5623951	29021799	GH-S	2	conceived and designed the proteomics experiments|performed the mass spectrometry experiments and data analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5623951	29021799	MW	2	conceived and designed the proteomics experiments	conceived and designed the proteomics experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5623951	29021799	PW	2	conceived all other experiments	conceived all other experiments	Conceived and designed the experiments	Conceptualization	YES
5623951	29021799	RR	2	conceived and designed the proteomics experiments|conceived all other experiments|performed all other experiments	conceived and designed the proteomics experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5623951	29021799	RR	2	conceived and designed the proteomics experiments|conceived all other experiments|performed all other experiments	conceived all other experiments	Conceived and designed the experiments	Conceptualization	YES
5623951	29021799	RR	2	conceived and designed the proteomics experiments|conceived all other experiments|performed all other experiments	performed all other experiments	Performed the experiments	Investigation	YES
5978669	29485724	AMPATH	3	Healthcare	Healthcare	-	-	NO
5978669	29485724	CAPRISA	3	Africa	Africa	-	-	NO
5978669	29485724	ICAP	3	Models	Models	Performed the experiments	Methodology	YES
5682871	28616762	AH	2	processed the cmr data and histology	processed the cmr data and histology	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5682871	28616762	AV	2	participated in its design and coordination and helped to draft the manuscript	participated in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Project administration|Writing - Original Draft	YES
5682871	28616762	FA	2	participated in its design and coordination and helped to draft the manuscript	participated in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Project administration|Writing - Original Draft	YES
5682871	28616762	FvS	2	processed the cmr data and helped drafting the manuscript	processed the cmr data and helped drafting the manuscript	Analyzed the data|Wrote the paper	Data curation|Writing - Original Draft	YES
5682871	28616762	JG	2	conceived the study, carried out the experiments, processed the cmr data and histology and drafted the manuscript	conceived the study, carried out the experiments, processed the cmr data and histology and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Data curation|Investigation|Writing - Original Draft	YES
5682871	28616762	JvO	2	performed the cmr experiments	performed the cmr experiments	Performed the experiments	Investigation	YES
5682871	28616762	PD	2	participated in its design and coordination and helped to draft the manuscript	participated in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Project administration|Writing - Original Draft	YES
5682871	28616762	RvE	2	participated in the design of the study, processed the cmr data and histology, performed the statistical analysis and helped drafting the manuscript	participated in the design of the study, processed the cmr data and histology, performed the statistical analysis and helped drafting the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5682871	28616762	SC	2	participated in its design and coordination and helped to draft the manuscript	participated in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Project administration|Writing - Original Draft	YES
5682871	28616762	SJ	2	conceived the study and carried out the experiments	conceived the study and carried out the experiments	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5682871	28616762	TL	2	participated in its design and coordination and helped to draft the manuscript	participated in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Project administration|Writing - Original Draft	YES
5441008	28532390	AB	2	contributed to the experimental design	contributed to the experimental design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5441008	28532390	BP	2	contributed to the experimental design	contributed to the experimental design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5441008	28532390	DL	2	contributed to the experimental design	contributed to the experimental design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5441008	28532390	GK	2	contributed to the experimental design	contributed to the experimental design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5441008	28532390	JB	2	with feedback from all others	with feedback from all others	-	-	NO
5441008	28532390	JF	2	contributed to the experimental design|with feedback from all others	contributed to the experimental design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5441008	28532390	JF	2	contributed to the experimental design|with feedback from all others	with feedback from all others	-	-	NO
5441008	28532390	MS	2	contributed to the experimental design	contributed to the experimental design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5441008	28532390	RV	2	contributed to the experimental design	contributed to the experimental design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4409298	25909848	BC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409298	25909848	BC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4409298	25909848	BC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4409298	25909848	BC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409298	25909848	CPHV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409298	25909848	CPHV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409298	25909848	CPHV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409298	25909848	CPHV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409298	25909848	CPHV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409298	25909848	ET	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4409298	25909848	ET	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4409298	25909848	ET	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409298	25909848	JA	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409298	25909848	JA	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409298	25909848	JA	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409298	25909848	JA	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409298	25909848	KY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409298	25909848	KY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409298	25909848	KY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409298	25909848	KY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409298	25909848	KY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409298	25909848	LL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409298	25909848	LL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409298	25909848	LL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409298	25909848	MF	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4409298	25909848	MF	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409298	25909848	PB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4409298	25909848	PB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1764037	17206275	BC	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1764037	17206275	BC	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1764037	17206275	CH	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1764037	17206275	HA	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1764037	17206275	HA	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1764037	17206275	JB	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1764037	17206275	JC	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1764037	17206275	RA	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1764037	17206275	SB	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1764037	17206275	SB	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1764037	17206275	SQ	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1764037	17206275	SS	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1764037	17206275	WT	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5623955	29021802	BJ	PLoS52	designed the research|analyzed the data|wrote the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
5623955	29021802	BJ	PLoS52	designed the research|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5623955	29021802	BJ	PLoS52	designed the research|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5623955	29021802	GC	PLoS52	designed the research|performed the research|analyzed the data|wrote the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
5623955	29021802	GC	PLoS52	designed the research|performed the research|analyzed the data|wrote the manuscript	performed the research	Performed the experiments	Investigation	YES
5623955	29021802	GC	PLoS52	designed the research|performed the research|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5623955	29021802	GC	PLoS52	designed the research|performed the research|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5623955	29021802	JC	PLoS52	performed the research	performed the research	Performed the experiments	Investigation	YES
5623955	29021802	LW	PLoS52	performed the research	performed the research	Performed the experiments	Investigation	YES
5623955	29021802	YZ	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5623955	29021802	ZL	PLoS52	performed the research	performed the research	Performed the experiments	Investigation	YES
5978682	29633559	AEP	2	read and critically reviewed the manuscript draft	read and critically reviewed the manuscript draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5978682	29633559	AR	2	designed the data collection tool and manuscript concept|read and critically reviewed the manuscript draft	designed the data collection tool and manuscript concept	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5978682	29633559	AR	2	designed the data collection tool and manuscript concept|read and critically reviewed the manuscript draft	read and critically reviewed the manuscript draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5978682	29633559	CB	2	read and critically reviewed the manuscript draft	read and critically reviewed the manuscript draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5978682	29633559	FLA	2	designed the data collection tool and manuscript concept|read and critically reviewed the manuscript draft	designed the data collection tool and manuscript concept	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5978682	29633559	FLA	2	designed the data collection tool and manuscript concept|read and critically reviewed the manuscript draft	read and critically reviewed the manuscript draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5978682	29633559	GVM	2	read and critically reviewed the manuscript draft	read and critically reviewed the manuscript draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5978682	29633559	HCV	2	elimination in hiv co-infected populations initiatives and studies	elimination in hiv co-infected populations initiatives and studies	-	-	NO
5978682	29633559	JSD	2	designed the data collection tool and manuscript concept|read and critically reviewed the manuscript draft	designed the data collection tool and manuscript concept	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5978682	29633559	JSD	2	designed the data collection tool and manuscript concept|read and critically reviewed the manuscript draft	read and critically reviewed the manuscript draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5978682	29633559	KL	2	read and critically reviewed the manuscript draft	read and critically reviewed the manuscript draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5978682	29633559	MBK	2	read and critically reviewed the manuscript draft	read and critically reviewed the manuscript draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5978682	29633559	MEH	2	designed the data collection tool and manuscript concept|read and critically reviewed the manuscript draft	designed the data collection tool and manuscript concept	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5978682	29633559	MEH	2	designed the data collection tool and manuscript concept|read and critically reviewed the manuscript draft	read and critically reviewed the manuscript draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5978682	29633559	MP	2	read and critically reviewed the manuscript draft	read and critically reviewed the manuscript draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5978682	29633559	MvdV	2	read and critically reviewed the manuscript draft	read and critically reviewed the manuscript draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5978682	29633559	NC	2	read and critically reviewed the manuscript draft	read and critically reviewed the manuscript draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5978682	29633559	RSD	2	designed the data collection tool and manuscript concept|wrote the first draft of the manuscript	designed the data collection tool and manuscript concept	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5978682	29633559	RSD	2	designed the data collection tool and manuscript concept|wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
5978682	29633559	SS	2	read and critically reviewed the manuscript draft	read and critically reviewed the manuscript draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3637083	23557152	All authors	2	have been involved in drafting the manuscript or revising it critically for the important intellectual content	have been involved in drafting the manuscript or revising it critically for the important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3637083	23557152	BB	2	have made substantial contributions to conception and design|are involved in the acquisition of data|are responsible for the analysis and interpretation of data	have made substantial contributions to conception and design	Conceived and designed the experiments	Conceptualization	YES
3637083	23557152	BB	2	have made substantial contributions to conception and design|are involved in the acquisition of data|are responsible for the analysis and interpretation of data	are involved in the acquisition of data	Performed the experiments	Investigation	YES
3637083	23557152	BB	2	have made substantial contributions to conception and design|are involved in the acquisition of data|are responsible for the analysis and interpretation of data	are responsible for the analysis and interpretation of data	Analyzed the data	Formal analysis	YES
3637083	23557152	FC	2	are responsible for the analysis and interpretation of data	are responsible for the analysis and interpretation of data	Analyzed the data	Formal analysis	YES
3637083	23557152	FD	2	have made substantial contributions to conception and design|are involved in the acquisition of data|are responsible for the analysis and interpretation of data	have made substantial contributions to conception and design	Conceived and designed the experiments	Conceptualization	YES
3637083	23557152	FD	2	have made substantial contributions to conception and design|are involved in the acquisition of data|are responsible for the analysis and interpretation of data	are involved in the acquisition of data	Performed the experiments	Investigation	YES
3637083	23557152	FD	2	have made substantial contributions to conception and design|are involved in the acquisition of data|are responsible for the analysis and interpretation of data	are responsible for the analysis and interpretation of data	Analyzed the data	Formal analysis	YES
3637083	23557152	GB	2	are involved in the acquisition of data	are involved in the acquisition of data	Performed the experiments	Investigation	YES
3637083	23557152	GC	2	are involved in the acquisition of data	are involved in the acquisition of data	Performed the experiments	Investigation	YES
3637083	23557152	GG	2	are involved in the acquisition of data	are involved in the acquisition of data	Performed the experiments	Investigation	YES
3637083	23557152	LP	2	are involved in the acquisition of data	are involved in the acquisition of data	Performed the experiments	Investigation	YES
3637083	23557152	PC	2	are involved in the acquisition of data	are involved in the acquisition of data	Performed the experiments	Investigation	YES
3637083	23557152	PM	2	are responsible for the analysis and interpretation of data	are responsible for the analysis and interpretation of data	Analyzed the data	Formal analysis	YES
3637083	23557152	TC	2	are responsible for the analysis and interpretation of data	are responsible for the analysis and interpretation of data	Analyzed the data	Formal analysis	YES
5441073	28532434	All authors	2	were responsible for critical review and approval of the manuscript	were responsible for critical review and approval of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5441073	28532434	BMG	2	were responsible for the study design|were responsible for the first draft of the manuscript	were responsible for the study design	Conceived and designed the experiments	Methodology	YES
5441073	28532434	BMG	2	were responsible for the study design|were responsible for the first draft of the manuscript	were responsible for the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
5441073	28532434	CLT	2	were responsible for the study design	were responsible for the study design	Conceived and designed the experiments	Methodology	YES
5441073	28532434	DAC	2	were responsible for obtaining the isolates and the epidemiological data and preparing the dna for sequencing	were responsible for obtaining the isolates and the epidemiological data and preparing the dna for sequencing	Performed the experiments	Investigation	YES
5441073	28532434	DDM	2	were responsible for obtaining the isolates and the epidemiological data and preparing the dna for sequencing	were responsible for obtaining the isolates and the epidemiological data and preparing the dna for sequencing	Performed the experiments	Investigation	YES
5441073	28532434	JEB	2	was responsible for the genome assembly	was responsible for the genome assembly	-	-	NO
5441073	28532434	JL	2	were responsible for obtaining the isolates and the epidemiological data and preparing the dna for sequencing	were responsible for obtaining the isolates and the epidemiological data and preparing the dna for sequencing	Performed the experiments	Investigation	YES
5441073	28532434	JS	2	were responsible for the study design	were responsible for the study design	Conceived and designed the experiments	Methodology	YES
5441073	28532434	KD	2	were responsible for the study design|were responsible for the genome analysis|were responsible for the first draft of the manuscript	were responsible for the study design	Conceived and designed the experiments	Methodology	YES
5441073	28532434	KD	2	were responsible for the study design|were responsible for the genome analysis|were responsible for the first draft of the manuscript	were responsible for the genome analysis	-	-	NO
5441073	28532434	KD	2	were responsible for the study design|were responsible for the genome analysis|were responsible for the first draft of the manuscript	were responsible for the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
5441073	28532434	KG	2	were responsible for obtaining the isolates and the epidemiological data and preparing the dna for sequencing	were responsible for obtaining the isolates and the epidemiological data and preparing the dna for sequencing	Performed the experiments	Investigation	YES
5441073	28532434	MCJM	2	were responsible for the study design|were responsible for the genome analysis|were responsible for the first draft of the manuscript	were responsible for the study design	Conceived and designed the experiments	Methodology	YES
5441073	28532434	MCJM	2	were responsible for the study design|were responsible for the genome analysis|were responsible for the first draft of the manuscript	were responsible for the genome analysis	-	-	NO
5441073	28532434	MCJM	2	were responsible for the study design|were responsible for the genome analysis|were responsible for the first draft of the manuscript	were responsible for the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
5441073	28532434	MHK	2	were responsible for obtaining the isolates and the epidemiological data and preparing the dna for sequencing	were responsible for obtaining the isolates and the epidemiological data and preparing the dna for sequencing	Performed the experiments	Investigation	YES
5441073	28532434	OBH	2	were responsible for the genome analysis|were responsible for the first draft of the manuscript	were responsible for the genome analysis	-	-	NO
5441073	28532434	OBH	2	were responsible for the genome analysis|were responsible for the first draft of the manuscript	were responsible for the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
5441073	28532434	OM	2	were responsible for the study design	were responsible for the study design	Conceived and designed the experiments	Methodology	YES
1764038	17206279	DB	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1764038	17206279	DB	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1764038	17206279	HQ	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1764038	17206279	HQ	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409300	25909360	J-DX	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409300	25909360	L-ZL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409300	25909360	L-ZL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409300	25909360	L-ZL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409300	25909360	L-ZL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409300	25909360	LC	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409300	25909360	LC	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409300	25909360	Q-FZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409300	25909360	S-DZ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409300	25909360	S-DZ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409300	25909360	S-DZ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409300	25909360	S-DZ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5978684	29633554	KL	2	conceptualized and outlined the paper|wrote the introduction, summarized the articles and contributed to the conclusions	conceptualized and outlined the paper	Conceived and designed the experiments	Conceptualization	YES
5978684	29633554	KL	2	conceptualized and outlined the paper|wrote the introduction, summarized the articles and contributed to the conclusions	wrote the introduction, summarized the articles and contributed to the conclusions	Wrote the paper	Writing - Original Draft	YES
5978684	29633554	MK	2	conceptualized and outlined the paper|wrote the introduction, summarized the articles and contributed to the conclusions	conceptualized and outlined the paper	Conceived and designed the experiments	Conceptualization	YES
5978684	29633554	MK	2	conceptualized and outlined the paper|wrote the introduction, summarized the articles and contributed to the conclusions	wrote the introduction, summarized the articles and contributed to the conclusions	Wrote the paper	Writing - Original Draft	YES
3637362	23587060	ES	2	participated in the design of the study and performed the statistical analysis	participated in the design of the study and performed the statistical analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
3637362	23587060	JH	2	participated in the design of the study and performed the statistical analysis	participated in the design of the study and performed the statistical analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
3637362	23587060	KI	2	participated in the design of the study and performed the statistical analysis	participated in the design of the study and performed the statistical analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
4538583	26339636	Shiva Marthandan	2	contributed equally to this work	contributed equally to this work	-	-	NO
4538583	26339636	Steffen Priebe	2	contributed equally to this work	contributed equally to this work	-	-	NO
5442658	28535746	JJ	1	Performed the experiments and analyzed the data|Wrote the manuscript	Performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5442658	28535746	JJ	1	Performed the experiments and analyzed the data|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5442658	28535746	JSP	1	Performed the experiments and analyzed the data	Performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5442658	28535746	MVA	1	Performed the experiments and analyzed the data	Performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5442658	28535746	NAA	1	Performed the experiments and analyzed the data	Performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5442658	28535746	SJB	1	Performed the experiments and analyzed the data|Wrote the manuscript	Performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5442658	28535746	SJB	1	Performed the experiments and analyzed the data|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5442658	28535746	SUP	1	Conception and design of the experiments|Wrote the manuscript	Conception and design of the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5442658	28535746	SUP	1	Conception and design of the experiments|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5442658	28535746	YP	1	Performed the experiments and analyzed the data	Performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5623956	29021800	All authors	2	agreed to be accountable for the content of the work	agreed to be accountable for the content of the work	-	-	NO
5623956	29021800	All the authors	2	showed the final approval of the version to be published	showed the final approval of the version to be published	-	-	NO
5978692	29485746	AP	2	contributed to study design, development of data collection instruments and the protocol, study oversight and implementation, data interpretation, data analysis and writing of this manuscript	contributed to study design, development of data collection instruments and the protocol, study oversight and implementation, data interpretation, data analysis and writing of this manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Supervision|Writing - Original Draft	YES
5978692	29485746	AS	2	contributed to study design, development of data collection instruments and the protocol, study oversight and implementation, data interpretation, data analysis and writing of this manuscript	contributed to study design, development of data collection instruments and the protocol, study oversight and implementation, data interpretation, data analysis and writing of this manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Supervision|Writing - Original Draft	YES
5978692	29485746	CM	2	contributed to study design, development of data collection instruments and the protocol, study oversight and implementation, and editing of this manuscript	contributed to study design, development of data collection instruments and the protocol, study oversight and implementation, and editing of this manuscript	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Methodology|Resources|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
5978692	29485746	JKE	2	contributed to data analysis, data interpretation and writing of this manuscript	contributed to data analysis, data interpretation and writing of this manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5978692	29485746	JPH	2	contributed to study design, development of the protocol, data interpretation and editing of this manuscript	contributed to study design, development of the protocol, data interpretation and editing of this manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5978692	29485746	JW	2	contributed to data analysis, data interpretation and editing of the manuscript	contributed to data analysis, data interpretation and editing of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5978692	29485746	KK	2	contributed to study design, development of data collection instruments and the protocol, study oversight and implementation, and editing of this manuscript	contributed to study design, development of data collection instruments and the protocol, study oversight and implementation, and editing of this manuscript	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Methodology|Resources|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
5978692	29485746	KNK	2	contributed to data analysis, data interpretation and writing of this manuscript	contributed to data analysis, data interpretation and writing of this manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5978692	29485746	RT	2	contributed to the protocol development, study implementation and oversight, and editing of the manuscript	contributed to the protocol development, study implementation and oversight, and editing of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
5978692	29485746	RW	2	contributed to study implementation and oversight, and editing of the manuscript	contributed to study implementation and oversight, and editing of the manuscript	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Review & Editing	YES
4409301	25909957	AP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Mathematics aspects	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409301	25909957	AP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Mathematics aspects	Analyzed the data	Analyzed the data	Formal analysis	YES
4409301	25909957	AP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Mathematics aspects	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409301	25909957	AP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Mathematics aspects	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409301	25909957	AP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Mathematics aspects	Mathematics aspects	-	-	NO
4409301	25909957	DE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Biological and toxicological aspects	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409301	25909957	DE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Biological and toxicological aspects	Performed the experiments	Performed the experiments	Investigation	YES
4409301	25909957	DE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Biological and toxicological aspects	Analyzed the data	Analyzed the data	Formal analysis	YES
4409301	25909957	DE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Biological and toxicological aspects	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409301	25909957	DE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Biological and toxicological aspects	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409301	25909957	DE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Biological and toxicological aspects	Biological and toxicological aspects	Performed the experiments	Investigation	YES
4409301	25909957	FR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Biological and toxicological aspects	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409301	25909957	FR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Biological and toxicological aspects	Performed the experiments	Performed the experiments	Investigation	YES
4409301	25909957	FR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Biological and toxicological aspects	Analyzed the data	Analyzed the data	Formal analysis	YES
4409301	25909957	FR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Biological and toxicological aspects	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409301	25909957	FR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Biological and toxicological aspects	Biological and toxicological aspects	Performed the experiments	Investigation	YES
4409301	25909957	GL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Biological and toxicological aspects	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409301	25909957	GL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Biological and toxicological aspects	Analyzed the data	Analyzed the data	Formal analysis	YES
4409301	25909957	GL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Biological and toxicological aspects	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409301	25909957	GL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Biological and toxicological aspects	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409301	25909957	GL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Biological and toxicological aspects	Biological and toxicological aspects	Performed the experiments	Investigation	YES
4409301	25909957	MF	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4409301	25909957	MF	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4409301	25909957	MF	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409301	25909957	NJ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Biological and toxicological aspects	Performed the experiments	Performed the experiments	Investigation	YES
4409301	25909957	NJ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Biological and toxicological aspects	Analyzed the data	Analyzed the data	Formal analysis	YES
4409301	25909957	NJ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Biological and toxicological aspects	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409301	25909957	NJ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Biological and toxicological aspects	Biological and toxicological aspects	Performed the experiments	Investigation	YES
4409301	25909957	RB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Mathematics aspects	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409301	25909957	RB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Mathematics aspects	Performed the experiments	Performed the experiments	Investigation	YES
4409301	25909957	RB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Mathematics aspects	Analyzed the data	Analyzed the data	Formal analysis	YES
4409301	25909957	RB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Mathematics aspects	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409301	25909957	RB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Mathematics aspects	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409301	25909957	RB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Mathematics aspects	Mathematics aspects	-	-	NO
1764039	17206276	HN	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1764039	17206276	HN	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1764039	17206276	HN	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1764039	17206276	MY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1764039	17206276	MY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1764039	17206276	MY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1764039	17206276	MY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1764039	17206276	NK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1764039	17206276	NK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1764039	17206276	NK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3637524	23618099	HA	2	provided the clinical data	provided the clinical data	Contributed reagents/materials/analysis tools	Resources	YES
3637524	23618099	HT	2	performed the study design and contributed to the intellectual discussion	performed the study design and contributed to the intellectual discussion	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3637524	23618099	KF	2	provided the clinical data	provided the clinical data	Contributed reagents/materials/analysis tools	Resources	YES
3637524	23618099	KH	2	provided the clinical data	provided the clinical data	Contributed reagents/materials/analysis tools	Resources	YES
3637524	23618099	KY	2	performed the study design and contributed to the intellectual discussion	performed the study design and contributed to the intellectual discussion	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3637524	23618099	MM	2	provided the clinical data	provided the clinical data	Contributed reagents/materials/analysis tools	Resources	YES
3637524	23618099	MS	2	carried out the data analysis and interpretation and drafted the manuscript	carried out the data analysis and interpretation and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3637524	23618099	SW	2	provided the clinical data	provided the clinical data	Contributed reagents/materials/analysis tools	Resources	YES
3637524	23618099	TM	2	performed the study design and contributed to the intellectual discussion	performed the study design and contributed to the intellectual discussion	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3637524	23618099	YK	2	performed the study design and contributed to the intellectual discussion	performed the study design and contributed to the intellectual discussion	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5623981	29021801	BF	2	gave critical revision of the article	gave critical revision of the article	Wrote the paper	Writing - Review & Editing	YES
5623981	29021801	VM	2	gave critical revision of the article	gave critical revision of the article	Wrote the paper	Writing - Review & Editing	YES
5623981	29021801	WQ	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5442662	28535807	CAM	2	conceptualised the study and drafted the manuscript	conceptualised the study and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5442662	28535807	KWB	2	developed the genome and transcriptome databases, and assisted in drafting the manuscript	developed the genome and transcriptome databases, and assisted in drafting the manuscript	Contributed reagents/materials/analysis tools|Wrote the paper	Software|Writing - Original Draft	YES
5442662	28535807	MRH	2	conceptualised the study and drafted the manuscript	conceptualised the study and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5442662	28535807	NS	2	developed the genome and transcriptome databases, and assisted in drafting the manuscript	developed the genome and transcriptome databases, and assisted in drafting the manuscript	Contributed reagents/materials/analysis tools|Wrote the paper	Software|Writing - Original Draft	YES
5442662	28535807	REB	2	performed lab work, analysis and drafted the manuscript	performed lab work, analysis and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5442662	28535807	SFC	2	conceptualised the study and drafted the manuscript	conceptualised the study and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
1764644	17225862	AN	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1764644	17225862	AN	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1764644	17225862	DA	PLoS5	Offered expert advice on interpretation of data and manuscript preparation	Offered expert advice on interpretation of data and manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
1764644	17225862	KW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1764644	17225862	KW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1764644	17225862	KW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1764644	17225862	LY	PLoS5	Offered expert advice on interpretation of data and manuscript preparation	Offered expert advice on interpretation of data and manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
1764644	17225862	SA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1764644	17225862	SA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1764644	17225862	SA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1764644	17225862	SY	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1764644	17225862	SY	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
3639813	23618132	IS	2	performed the tem studies	performed the tem studies	Performed the experiments	Investigation	YES
3639813	23618132	KH	2	participated in the conduct of the study|participated in the study coordination, image analysis, and data analysis	participated in the conduct of the study	Performed the experiments	Investigation	YES
3639813	23618132	KH	2	participated in the conduct of the study|participated in the study coordination, image analysis, and data analysis	participated in the study coordination, image analysis, and data analysis	Analyzed the data	Formal analysis|Project administration|Visualization	YES
3639813	23618132	MaT	2	participated in the design of the study, performed the statistical analyses, and drafted the manuscript|participated in the conduct of the study|participated in the study coordination, image analysis, and data analysis	participated in the design of the study, performed the statistical analyses, and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3639813	23618132	MaT	2	participated in the design of the study, performed the statistical analyses, and drafted the manuscript|participated in the conduct of the study|participated in the study coordination, image analysis, and data analysis	participated in the conduct of the study	Performed the experiments	Investigation	YES
3639813	23618132	MaT	2	participated in the design of the study, performed the statistical analyses, and drafted the manuscript|participated in the conduct of the study|participated in the study coordination, image analysis, and data analysis	participated in the study coordination, image analysis, and data analysis	Analyzed the data	Formal analysis|Project administration|Visualization	YES
3639813	23618132	MiT	2	participated in the conduct of the study	participated in the conduct of the study	Performed the experiments	Investigation	YES
3639813	23618132	NT	2	prepared the pamam-grafted silica nanoparticles and executed the zeta potential measurements and the sem studies	prepared the pamam-grafted silica nanoparticles and executed the zeta potential measurements and the sem studies	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4409302	25909910	FH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409302	25909910	JL	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409302	25909910	PW	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4409302	25909910	PW	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409302	25909910	SX	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409302	25909910	SX	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409302	25909910	YL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409302	25909910	ZH	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409302	25909910	ZYW	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5624289	29021797	LC	1	Study conception and design	Study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5624289	29021797	PZ	1	Study conception and design	Study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5624289	29021797	SC	1	Study conception and design	Study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5624289	29021797	YZ	1	Study conception and design	Study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
1764646	17215957	CL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1764646	17215957	CL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1764646	17215957	CL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1764646	17215957	CL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1764646	17215957	CL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1764646	17215957	DC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1764646	17215957	DC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1764646	17215957	DC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1764646	17215957	DC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1764646	17215957	JH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1764646	17215957	JH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1764646	17215957	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1764646	17215957	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1764646	17215957	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1764646	17215957	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1764646	17215957	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1764646	17215957	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1764646	17215957	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1764646	17215957	PS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1764646	17215957	TR	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1764646	17215957	TR	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1764646	17215957	TR	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5442678	28539120	BAM	2	recruited patients	recruited patients	Performed the experiments	Investigation	YES
5442678	28539120	CNB	2	recruited patients	recruited patients	Performed the experiments	Investigation	YES
5442678	28539120	CvK	2	performed n of 1 study for patient 45	performed n of 1 study for patient 45	Performed the experiments	Investigation	YES
5442678	28539120	ELL	2	performed secondary control study and bootstrap analysis	performed secondary control study and bootstrap analysis	Performed the experiments	Investigation	YES
5442678	28539120	FRZ	2	conceived and designed the study, interpreted the data and wrote and reviewed the manuscript|managed the study, and conducted the objective pathway analyses for wgs data	conceived and designed the study, interpreted the data and wrote and reviewed the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5442678	28539120	FRZ	2	conceived and designed the study, interpreted the data and wrote and reviewed the manuscript|managed the study, and conducted the objective pathway analyses for wgs data	managed the study, and conducted the objective pathway analyses for wgs data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Data curation|Formal analysis|Investigation|Project administration	YES
5442678	28539120	H-YEC	2	performed gene regulatory region variation analyses and participated in secondary control study	performed gene regulatory region variation analyses and participated in secondary control study	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5442678	28539120	JM	2	performed n of 1 analyses of wgs data and copy number analyses, and provided editorial input	performed n of 1 analyses of wgs data and copy number analyses, and provided editorial input	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5442678	28539120	JMF	2	conceived and designed the study, interpreted the data and wrote and reviewed the manuscript	conceived and designed the study, interpreted the data and wrote and reviewed the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5442678	28539120	KM	2	performed abyss indel analysis	performed abyss indel analysis	Performed the experiments	Investigation	YES
5442678	28539120	LL	2	extracted dna and performed sanger verification	extracted dna and performed sanger verification	Performed the experiments	Investigation|Validation	YES
5442678	28539120	LLA	2	recruited patients	recruited patients	Performed the experiments	Investigation	YES
5442678	28539120	MAM	2	conceived and designed the study, interpreted the data and wrote and reviewed the manuscript	conceived and designed the study, interpreted the data and wrote and reviewed the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5442678	28539120	MC	2	performed tad analyses for regulatory region study	performed tad analyses for regulatory region study	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5442678	28539120	NM	2	recruited patients	recruited patients	Performed the experiments	Investigation	YES
5442678	28539120	PB	2	obtained research ethics boards approvals	obtained research ethics boards approvals	-	Project administration	YES
5442678	28539120	SLL	2	recruited patients	recruited patients	Performed the experiments	Investigation	YES
3640965	23618062	AH	2	led the study in total	led the study in total	-	-	NO
3640965	23618062	ATakano	2	analyzed the pet image data|drafted the manuscript	analyzed the pet image data	Analyzed the data	Formal analysis|Visualization	YES
3640965	23618062	ATakano	2	analyzed the pet image data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
3640965	23618062	AV	2	performed pet measurements|analyzed the pet image data	performed pet measurements	Performed the experiments	Investigation	YES
3640965	23618062	AV	2	performed pet measurements|analyzed the pet image data	analyzed the pet image data	Analyzed the data	Formal analysis|Visualization	YES
3640965	23618062	All authors	2	participated in the development of the study design|contributed to the interpretation of the study results|critically reviewed the manuscript and approved the final manuscript	participated in the development of the study design	Conceived and designed the experiments	Methodology	YES
3640965	23618062	All authors	2	participated in the development of the study design|contributed to the interpretation of the study results|critically reviewed the manuscript and approved the final manuscript	contributed to the interpretation of the study results	Analyzed the data	Formal analysis	YES
3640965	23618062	All authors	2	participated in the development of the study design|contributed to the interpretation of the study results|critically reviewed the manuscript and approved the final manuscript	critically reviewed the manuscript and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
3640965	23618062	BG	2	performed pet measurements	performed pet measurements	Performed the experiments	Investigation	YES
3640965	23618062	CH	2	led the study in total	led the study in total	-	-	NO
3640965	23618062	FP	2	recruited subjects	recruited subjects	Performed the experiments	Investigation	YES
3640965	23618062	JH	2	recruited subjects	recruited subjects	Performed the experiments	Investigation	YES
3640965	23618062	NAT	2	recruited subjects	recruited subjects	Performed the experiments	Investigation	YES
3640965	23618062	PS	2	performed pet measurements	performed pet measurements	Performed the experiments	Investigation	YES
3640965	23618062	SN	2	produced the pet radioligand	produced the pet radioligand	-	-	NO
3640965	23618062	TK	2	analyzed the mri data	analyzed the mri data	Analyzed the data	Formal analysis	YES
5625008	29033967	CL	2	critically edited the manuscript	critically edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5625008	29033967	FX	2	conceived and designed research|revised the manuscript	conceived and designed research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5625008	29033967	FX	2	conceived and designed research|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5625008	29033967	HoZ	2	helped in conducting the experiments and analyzing the data	helped in conducting the experiments and analyzing the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5625008	29033967	HuZ	2	critically edited the manuscript	critically edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5625008	29033967	J-JW	2	critically edited the manuscript	critically edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5625008	29033967	QZ	2	helped in conducting the experiments and analyzing the data	helped in conducting the experiments and analyzing the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5625008	29033967	XY	2	conceived and designed research|performed the experiments, analyzed the data, wrote the manuscript	conceived and designed research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5625008	29033967	XY	2	conceived and designed research|performed the experiments, analyzed the data, wrote the manuscript	performed the experiments, analyzed the data, wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4409303	25909320	CSH	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409303	25909320	CSH	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409303	25909320	CSH	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409303	25909320	CSH	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409303	25909320	PBA	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409303	25909320	PBA	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409303	25909320	PBA	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409303	25909320	PBA	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409303	25909320	SAS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409303	25909320	SAS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409303	25909320	SAS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409303	25909320	SAS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409303	25909320	SAS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3640969	23618081	All authors	2	contributed to the draft of the manuscript	contributed to the draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
3640969	23618081	EL	2	coordinated and interpreted the histological examination of all xenograft tissue specimens	coordinated and interpreted the histological examination of all xenograft tissue specimens	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Project administration	YES
3640969	23618081	FMM	2	participated in the design of the study and data analysis	participated in the design of the study and data analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
3640969	23618081	JVS	2	participated in the study design and helped monitoring the development of cell cultures and xenograft models	participated in the study design and helped monitoring the development of cell cultures and xenograft models	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Supervision	YES
3640969	23618081	KME	2	designed the experimental protocol, carried out the cell culture and development of the xenograft models, participated in and monitored the imaging of all animals and drafted the manuscript	designed the experimental protocol, carried out the cell culture and development of the xenograft models, participated in and monitored the imaging of all animals and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Investigation|Methodology|Supervision|Visualization|Writing - Original Draft	YES
3640969	23618081	LM	2	participated in the design of the study and data analysis	participated in the design of the study and data analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
3640969	23618081	MK	2	participated in the design of the study and data analysis	participated in the design of the study and data analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5978702	29485709	AG	2	collaborated on the design of the study|analyzed the data and wrote the paper	collaborated on the design of the study	Conceived and designed the experiments	Methodology	YES
5978702	29485709	AG	2	collaborated on the design of the study|analyzed the data and wrote the paper	analyzed the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5978702	29485709	All authors	2	provided critical intellectual input into the interpretation of results	provided critical intellectual input into the interpretation of results	Analyzed the data	Formal analysis	YES
5978702	29485709	JN	2	collaborated on the design of the study	collaborated on the design of the study	Conceived and designed the experiments	Methodology	YES
5978702	29485709	NMN	2	collaborated on the design of the study	collaborated on the design of the study	Conceived and designed the experiments	Methodology	YES
5978702	29485709	NT	2	collaborated on the design of the study	collaborated on the design of the study	Conceived and designed the experiments	Methodology	YES
5978702	29485709	SB	2	collaborated on the design of the study|analyzed the data and wrote the paper	collaborated on the design of the study	Conceived and designed the experiments	Methodology	YES
5978702	29485709	SB	2	collaborated on the design of the study|analyzed the data and wrote the paper	analyzed the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5978702	29485709	TM	2	collaborated on the design of the study	collaborated on the design of the study	Conceived and designed the experiments	Methodology	YES
1764683	17245446	HM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1764683	17245446	HM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1764683	17245446	SI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1764683	17245446	SI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1764683	17245446	SI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1764683	17245446	SI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1764683	17245446	TB	PLoS5	Wrote the paper|Supervised the entire project	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1764683	17245446	TB	PLoS5	Wrote the paper|Supervised the entire project	Supervised the entire project	-	Supervision	YES
1764683	17245446	WB	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
3648392	23618227	AA	PLoS52	contributed to the concept and design of the study|analyzed the data|critically contributed to the manuscript	contributed to the concept and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3648392	23618227	AA	PLoS52	contributed to the concept and design of the study|analyzed the data|critically contributed to the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
3648392	23618227	AA	PLoS52	contributed to the concept and design of the study|analyzed the data|critically contributed to the manuscript	critically contributed to the manuscript	-	-	NO
3648392	23618227	AJB	PLoS52	contributed to the concept and design of the study|acquired data on the subjects|analyzed the data	contributed to the concept and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3648392	23618227	AJB	PLoS52	contributed to the concept and design of the study|acquired data on the subjects|analyzed the data	acquired data on the subjects	Performed the experiments	Investigation	YES
3648392	23618227	AJB	PLoS52	contributed to the concept and design of the study|acquired data on the subjects|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
3648392	23618227	All authors	PLoS52	contributed substantially to the scientific process leading to this manuscript	contributed substantially to the scientific process leading to this manuscript	-	-	NO
3648392	23618227	EF	PLoS52	contributed to the concept and design of the study|analyzed the data	contributed to the concept and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3648392	23618227	EF	PLoS52	contributed to the concept and design of the study|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
3648392	23618227	EMG	PLoS52	acquired data on the subjects|critically contributed to the manuscript	acquired data on the subjects	Performed the experiments	Investigation	YES
3648392	23618227	EMG	PLoS52	acquired data on the subjects|critically contributed to the manuscript	critically contributed to the manuscript	-	-	NO
3648392	23618227	JB	PLoS52	contributed to the concept and design of the study|critically contributed to the manuscript	contributed to the concept and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3648392	23618227	JB	PLoS52	contributed to the concept and design of the study|critically contributed to the manuscript	critically contributed to the manuscript	-	-	NO
3648392	23618227	MLD	PLoS52	critically contributed to the manuscript	critically contributed to the manuscript	-	-	NO
3648392	23618227	PHB	PLoS52	contributed to the concept and design of the study	contributed to the concept and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5442695	28535780	AB	2	revised the draft and made contributions to the final manuscript	revised the draft and made contributions to the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5442695	28535780	KLM	2	revised the draft and made contributions to the final manuscript	revised the draft and made contributions to the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5442695	28535780	LFR	2	revised the draft and made contributions to the final manuscript	revised the draft and made contributions to the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5442695	28535780	MRW	2	supervised smc designed and performed the bioinformatic analysis under the|revised the draft and made contributions to the final manuscript	supervised smc designed and performed the bioinformatic analysis under the	Conceived and designed the experiments|Performed the experiments	Formal analysis|Investigation|Supervision	YES
5442695	28535780	MRW	2	supervised smc designed and performed the bioinformatic analysis under the|revised the draft and made contributions to the final manuscript	revised the draft and made contributions to the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5442695	28535780	SMC	2	designed and performed the bioinformatic analysis under the	designed and performed the bioinformatic analysis under the	Conceived and designed the experiments|Performed the experiments	Formal analysis|Investigation	YES
5625010	29033968	The author	2	confirms being the sole contributor of this work and approved it for publication	confirms being the sole contributor of this work and approved it for publication	-	-	NO
4409305	25909590	AM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409305	25909590	AMGA	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409305	25909590	AMGS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409305	25909590	AP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409305	25909590	AP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409305	25909590	AP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409305	25909590	AP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409305	25909590	JGE	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409305	25909590	JMM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409305	25909590	MJAG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409305	25909590	MJAG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4409305	25909590	MJAG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409305	25909590	NRL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409305	25909590	NRL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4409305	25909590	NRL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409305	25909590	SSR	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5978704	29633520	GH	2	conceptualized the main messages and provided comments on the paper	conceptualized the main messages and provided comments on the paper	Conceived and designed the experiments	Conceptualization	YES
5978704	29633520	MB	2	conceptualized the main messages and provided comments on the paper	conceptualized the main messages and provided comments on the paper	Conceived and designed the experiments	Conceptualization	YES
5978704	29633520	YH	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
3648448	23618039	ALK	2	devised the project, developed the methods, helped with the image acquisition, processed the data, and drafted the manuscript	devised the project, developed the methods, helped with the image acquisition, processed the data, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Data curation|Investigation|Methodology|Visualization|Writing - Original Draft	YES
3648448	23618039	EM	2	were involved in the image acquisition, project design, and drafting of the manuscript	were involved in the image acquisition, project design, and drafting of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Methodology|Visualization|Writing - Original Draft	YES
3648448	23618039	GA	2	were involved in the image acquisition, project design, and drafting of the manuscript	were involved in the image acquisition, project design, and drafting of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Methodology|Visualization|Writing - Original Draft	YES
3648448	23618039	PI	2	aided with the project design, data acquisition, and drafting of the manuscript	aided with the project design, data acquisition, and drafting of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
3648448	23618039	RS	2	were involved in drafting of the manuscript	were involved in drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
3648448	23618039	ST	2	were involved in drafting of the manuscript	were involved in drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
1764684	17225863	MC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1764684	17225863	MC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1764684	17225863	MC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1764684	17225863	RB	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1764684	17225863	RB	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5625070	29033957	AM	2	designed the sample|field sampling|do data analysis	designed the sample	Conceived and designed the experiments	-	YES
5625070	29033957	AM	2	designed the sample|field sampling|do data analysis	field sampling	Performed the experiments	Investigation	YES
5625070	29033957	AM	2	designed the sample|field sampling|do data analysis	do data analysis	Analyzed the data	Formal analysis	YES
5625070	29033957	DO	2	designed the sample|field sampling	designed the sample	Conceived and designed the experiments	-	YES
5625070	29033957	DO	2	designed the sample|field sampling	field sampling	Performed the experiments	Investigation	YES
5625070	29033957	O Wrote	2	the manuscript	the manuscript	-	-	NO
5625070	29033957	RC	2	designed the sample|field sampling|do data analysis	designed the sample	Conceived and designed the experiments	-	YES
5625070	29033957	RC	2	designed the sample|field sampling|do data analysis	field sampling	Performed the experiments	Investigation	YES
5625070	29033957	RC	2	designed the sample|field sampling|do data analysis	do data analysis	Analyzed the data	Formal analysis	YES
5625070	29033957	RI	2	designed the sample|do data analysis	designed the sample	Conceived and designed the experiments	-	YES
5625070	29033957	RI	2	designed the sample|do data analysis	do data analysis	Analyzed the data	Formal analysis	YES
3648494	23531207	All authors	2	edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
3648494	23531207	DD	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
3648494	23531207	JH	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
3648494	23531207	JL	2	supervised the clinical part of the paper	supervised the clinical part of the paper	-	Supervision	YES
3648494	23531207	LR	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5978710	29171172	AP	2	oversaw the review	oversaw the review	-	Supervision	YES
5978710	29171172	All	2	authors contributed to design and execution of the review, as well as to the interpretation of findings	authors contributed to design and execution of the review, as well as to the interpretation of findings	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5978710	29171172	PR	2	oversaw the review	oversaw the review	-	Supervision	YES
5978710	29171172	RVB	2	oversaw the review|wrote the first draft of the paper, which was revised by all authors|authors contributed to design and execution of the review, as well as to the interpretation of findings	oversaw the review	-	Supervision	YES
5978710	29171172	RVB	2	oversaw the review|wrote the first draft of the paper, which was revised by all authors|authors contributed to design and execution of the review, as well as to the interpretation of findings	wrote the first draft of the paper, which was revised by all authors	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5978710	29171172	RVB	2	oversaw the review|wrote the first draft of the paper, which was revised by all authors|authors contributed to design and execution of the review, as well as to the interpretation of findings	authors contributed to design and execution of the review, as well as to the interpretation of findings	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5442703	28535754	All authors	PLoS52	read and approved the finalized manuscript	read and approved the finalized manuscript	Wrote the paper	Writing - Review & Editing	YES
5442703	28535754	DD	PLoS52	contributed to the reagents	contributed to the reagents	Contributed reagents/materials/analysis tools	Resources	YES
5442703	28535754	JX	PLoS52	conceived and designed the experiments|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5442703	28535754	JX	PLoS52	conceived and designed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5442703	28535754	KL	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5442703	28535754	LF	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5442703	28535754	MQ	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5442703	28535754	QY	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5442703	28535754	QY	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5442703	28535754	RL	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5442703	28535754	SL	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5442703	28535754	TZ	PLoS52	contributed to the reagents	contributed to the reagents	Contributed reagents/materials/analysis tools	Resources	YES
5442703	28535754	The authors	PLoS52	report no potential conflicts of interest	report no potential conflicts of interest	-	-	NO
5442703	28535754	WC	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5442703	28535754	XZ	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5442703	28535754	XZ	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5442703	28535754	XZ	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5442703	28535754	XZ	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5442703	28535754	YL	PLoS52	contributed to the reagents	contributed to the reagents	Contributed reagents/materials/analysis tools	Resources	YES
5442703	28535754	YY	PLoS52	contributed to the reagents	contributed to the reagents	Contributed reagents/materials/analysis tools	Resources	YES
4409306	25909986	CT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409306	25909986	CT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409306	25909986	CT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409306	25909986	CT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409306	25909986	CT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409306	25909986	LJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409306	25909986	LJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409306	25909986	LJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409306	25909986	LJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409306	25909986	LJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5847211	29043465	AM	2	were local principal investigators	were local principal investigators	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
5847211	29043465	AZ	2	were a major contributor in writing the manuscript	were a major contributor in writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5847211	29043465	BG	2	performed the statistical analyses	performed the statistical analyses	Analyzed the data	Formal analysis	YES
5847211	29043465	CA	2	were local principal investigators|were a major contributor in writing the manuscript	were local principal investigators	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
5847211	29043465	CA	2	were local principal investigators|were a major contributor in writing the manuscript	were a major contributor in writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5847211	29043465	CMR	2	feature tracking and tagging	feature tracking and tagging	-	-	NO
5847211	29043465	FL	2	were local principal investigators	were local principal investigators	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
5847211	29043465	IG	2	were central principal investigators	were central principal investigators	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
5847211	29043465	KV	2	were local principal investigators	were local principal investigators	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
5847211	29043465	MC	2	analyzed and interpreted the patient data regarding the echocardiograms and speckle tracking analysis|were a major contributor in writing the manuscript	analyzed and interpreted the patient data regarding the echocardiograms and speckle tracking analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5847211	29043465	MC	2	analyzed and interpreted the patient data regarding the echocardiograms and speckle tracking analysis|were a major contributor in writing the manuscript	were a major contributor in writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5847211	29043465	MM	2	were local principal investigators	were local principal investigators	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
5847211	29043465	MR	2	performed the statistical analyses	performed the statistical analyses	Analyzed the data	Formal analysis	YES
5847211	29043465	MV	2	were central principal investigators	were central principal investigators	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
5847211	29043465	PC	2	assisted with the cmr tagging software|assisted with the cmr tagging software	assisted with the cmr tagging software	Contributed reagents/materials/analysis tools	Software	YES
5847211	29043465	PC	2	assisted with the cmr tagging software|assisted with the cmr tagging software	assisted with the cmr tagging software	Contributed reagents/materials/analysis tools	Software	YES
5847211	29043465	RN	2	were a major contributor in writing the manuscript	were a major contributor in writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5847211	29043465	WE	2	analyzed and interpreted the patient data regarding the echocardiograms and speckle tracking analysis|were a major contributor in writing the manuscript	analyzed and interpreted the patient data regarding the echocardiograms and speckle tracking analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5847211	29043465	WE	2	analyzed and interpreted the patient data regarding the echocardiograms and speckle tracking analysis|were a major contributor in writing the manuscript	were a major contributor in writing the manuscript	Wrote the paper	Writing - Original Draft	YES
3655042	23647774	AL	2	revised the manuscript for important intellectual content	revised the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
3655042	23647774	AP	2	participated in the design of the study, interpretation of data, and revised the manuscript for important intellectual content	participated in the design of the study, interpretation of data, and revised the manuscript for important intellectual content	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
3655042	23647774	AS	2	participated in the design of the study, interpretation of data, and revised the manuscript for important intellectual content	participated in the design of the study, interpretation of data, and revised the manuscript for important intellectual content	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
3655042	23647774	AV	2	revised the manuscript for important intellectual content	revised the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
3655042	23647774	CL	2	helped carrying out radiochemistry	helped carrying out radiochemistry	Performed the experiments	Investigation	YES
3655042	23647774	ES	2	revised the manuscript for important intellectual content	revised the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
3655042	23647774	FB	2	carried out the experiments, participated in the design of the study, and drafted the manuscript	carried out the experiments, participated in the design of the study, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
3655042	23647774	FG	2	helped carrying out radiochemistry	helped carrying out radiochemistry	Performed the experiments	Investigation	YES
3655042	23647774	FM	2	revised the manuscript for important intellectual content	revised the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
3655042	23647774	GW	2	carried out the experiments and participated in the design of the study	carried out the experiments and participated in the design of the study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3655042	23647774	JA	2	carried out radiochemistry	carried out radiochemistry	Performed the experiments	Investigation	YES
3655042	23647774	MAB	2	participated in the design of the study and interpretation of data	participated in the design of the study and interpretation of data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
3655042	23647774	NM	2	revised the manuscript for important intellectual content	revised the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
3655042	23647774	TB	2	revised the manuscript for important intellectual content	revised the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
1764709	17225854	AK	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1764709	17225854	AK	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1764709	17225854	GT	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1764709	17225854	GT	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1764709	17225854	IR	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1764709	17225854	IR	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1764709	17225854	MG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1764709	17225854	MG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1764709	17225854	MG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1764709	17225854	MM	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1764709	17225854	MM	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1764709	17225854	MW	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1764709	17225854	MW	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1764709	17225854	MW	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1764709	17225854	OK	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1764709	17225854	OK	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1764709	17225854	PR	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1764709	17225854	PR	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1764709	17225854	TP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1764709	17225854	ZM	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1764709	17225854	ZM	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409307	25909188	BvdB	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409307	25909188	DD	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409307	25909188	HB	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409307	25909188	IB	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409307	25909188	JR	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409307	25909188	JR	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409307	25909188	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409307	25909188	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409307	25909188	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409307	25909188	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409307	25909188	MR	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409307	25909188	MZ	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409307	25909188	MvdH	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409307	25909188	MvdH	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409307	25909188	NSvD	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409307	25909188	OS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409307	25909188	RdB	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4409307	25909188	RdB	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409307	25909188	TR	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409307	25909188	WvdG	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5625282	29033956	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5625282	29033956	FG	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5625282	29033956	JM	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5625282	29033956	JW	2	grew the plants and prepared the samples	grew the plants and prepared the samples	Performed the experiments	Investigation	YES
5625282	29033956	JZ	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5625282	29033956	LL	2	carried out most of the experiment, analyzed the transcriptome and digital gene expression data, wrote the methods part of the manuscript	carried out most of the experiment, analyzed the transcriptome and digital gene expression data, wrote the methods part of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5625282	29033956	NS	2	grew the plants and prepared the samples	grew the plants and prepared the samples	Performed the experiments	Investigation	YES
5625282	29033956	SW	2	designed the experiment and drafted the manuscript	designed the experiment and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5625282	29033956	SY	2	carried out most of the experiment, analyzed the transcriptome and digital gene expression data, wrote the methods part of the manuscript	carried out most of the experiment, analyzed the transcriptome and digital gene expression data, wrote the methods part of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5625282	29033956	XL	2	designed the experiment and drafted the manuscript	designed the experiment and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5625282	29033956	YG	2	grew the plants and prepared the samples	grew the plants and prepared the samples	Performed the experiments	Investigation	YES
5978711	29485714	AG	PLoS52	conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5978711	29485714	All authors	PLoS52	interpreted the data and contributed to writing the manuscript	interpreted the data and contributed to writing the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5978711	29485714	GF	PLoS52	conceived the study|designed the study|contributed to data collection and managed the data|analysed the data|drafted the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5978711	29485714	GF	PLoS52	conceived the study|designed the study|contributed to data collection and managed the data|analysed the data|drafted the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5978711	29485714	GF	PLoS52	conceived the study|designed the study|contributed to data collection and managed the data|analysed the data|drafted the manuscript	contributed to data collection and managed the data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5978711	29485714	GF	PLoS52	conceived the study|designed the study|contributed to data collection and managed the data|analysed the data|drafted the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
5978711	29485714	GF	PLoS52	conceived the study|designed the study|contributed to data collection and managed the data|analysed the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
3658936	23663426	EF	2	carried out the animal models and revised of the manuscript critically	carried out the animal models and revised of the manuscript critically	Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
3658936	23663426	GH	2	synthesised the precursors and radiotracers	synthesised the precursors and radiotracers	-	-	NO
3658936	23663426	HJW	2	took part in the conception and design, interpreting of the data and revision the manuscript	took part in the conception and design, interpreting of the data and revision the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Review & Editing	YES
3658936	23663426	HK	2	took part in the conception and design, interpreting of the data and revision the manuscript	took part in the conception and design, interpreting of the data and revision the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Review & Editing	YES
3658936	23663426	IL	2	took part in the conception and design, did the acquiring, analysing and interpreting of the data and wrote the manuscript	took part in the conception and design, did the acquiring, analysing and interpreting of the data and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
3658936	23663426	JN	2	synthesised the precursors and radiotracers|acquired and interpreted the data and revised the manuscript critically	synthesised the precursors and radiotracers	-	-	NO
3658936	23663426	JN	2	synthesised the precursors and radiotracers|acquired and interpreted the data and revised the manuscript critically	acquired and interpreted the data and revised the manuscript critically	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
3658936	23663426	KP	2	synthesised the precursors and radiotracers|acquired and interpreted the data and revised the manuscript critically	synthesised the precursors and radiotracers	-	-	NO
3658936	23663426	KP	2	synthesised the precursors and radiotracers|acquired and interpreted the data and revised the manuscript critically	acquired and interpreted the data and revised the manuscript critically	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
3658936	23663426	MR	2	took part in the conception and design, acquired, analysed and interpreted data	took part in the conception and design, acquired, analysed and interpreted data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation	YES
3658936	23663426	MS	2	took part in the conception and design, interpreting of the data and revision the manuscript	took part in the conception and design, interpreting of the data and revision the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Review & Editing	YES
3658936	23663426	SGN	2	is also involved in the interpretation of the in vivo data and revised the manuscript critically	is also involved in the interpretation of the in vivo data and revised the manuscript critically	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
3658936	23663426	SN	2	synthesised the precursors and radiotracers	synthesised the precursors and radiotracers	-	-	NO
5445270	28545403	AEW	PLoS52	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5445270	28545403	BSP	PLoS52	performed the statistical analysis of rna seq data	performed the statistical analysis of rna seq data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5445270	28545403	HW	PLoS52	processed rna seq data	processed rna seq data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5445270	28545403	IM	PLoS52	helped writing the manuscript and analyzed the data	helped writing the manuscript and analyzed the data	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5445270	28545403	JLD	PLoS52	helped with data analysis and manuscript assembly	helped with data analysis and manuscript assembly	Analyzed the data	Formal analysis	YES
5445270	28545403	KMW	PLoS52	helped writing the manuscript and analyzed the data	helped writing the manuscript and analyzed the data	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5445270	28545403	MR	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5445270	28545403	OV	PLoS52	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5445270	28545403	RJ	PLoS52	helped with data analysis and manuscript assembly	helped with data analysis and manuscript assembly	Analyzed the data	Formal analysis	YES
5445270	28545403	SS	PLoS52	performed the statistical analysis of rna seq data	performed the statistical analysis of rna seq data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5445270	28545403	SSF	PLoS52	processed rna seq data	processed rna seq data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
4196250	25328556	H.K.	2	contributed to conception and design, interpreted the data, and revised the article	contributed to conception and design, interpreted the data, and revised the article	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Resources|Writing - Review & Editing	YES
4196250	25328556	M.H.	2	contributed to conception and design, interpreted the data, and revised the article	contributed to conception and design, interpreted the data, and revised the article	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Resources|Writing - Review & Editing	YES
4196250	25328556	M.I.A.	2	performed experiments and drafted the article	performed experiments and drafted the article	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4196250	25328556	M.M.	2	performed experiments and drafted the article|contributed to conception and design, interpreted the data, and revised the article	performed experiments and drafted the article	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4196250	25328556	M.M.	2	performed experiments and drafted the article|contributed to conception and design, interpreted the data, and revised the article	contributed to conception and design, interpreted the data, and revised the article	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Resources|Writing - Review & Editing	YES
4196250	25328556	R.W.	2	contributed to conception and design, interpreted the data, and revised the article	contributed to conception and design, interpreted the data, and revised the article	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Resources|Writing - Review & Editing	YES
4196250	25328556	X.H.	2	contributed to conception and design, interpreted the data, and revised the article	contributed to conception and design, interpreted the data, and revised the article	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Resources|Writing - Review & Editing	YES
4196250	25328556	Y.N.	2	directed this study	directed this study	-	Supervision	YES
1764710	17225855	RK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1764710	17225855	RK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1764710	17225855	RK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1764710	17225855	VC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1764710	17225855	VC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1764710	17225855	VC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1764710	17225855	VC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5625325	29033965	AlK	2	carried out dna marker analysis and data analysis	carried out dna marker analysis and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5625325	29033965	All authors	2	approved the manuscript	approved the manuscript	-	-	NO
5625325	29033965	AnK	2	carried out dna marker analysis and data analysis|prepared plant materials and conducted insect resistance evaluation|wrote the manuscript	carried out dna marker analysis and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5625325	29033965	AnK	2	carried out dna marker analysis and data analysis|prepared plant materials and conducted insect resistance evaluation|wrote the manuscript	prepared plant materials and conducted insect resistance evaluation	Performed the experiments	Investigation	YES
5625325	29033965	AnK	2	carried out dna marker analysis and data analysis|prepared plant materials and conducted insect resistance evaluation|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5625325	29033965	JC	2	performed dna sequencing, and analyzed sequencing results|wrote the manuscript	performed dna sequencing, and analyzed sequencing results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5625325	29033965	JC	2	performed dna sequencing, and analyzed sequencing results|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5625325	29033965	PeS	2	prepared plant materials and conducted insect resistance evaluation|wrote the manuscript	prepared plant materials and conducted insect resistance evaluation	Performed the experiments	Investigation	YES
5625325	29033965	PeS	2	prepared plant materials and conducted insect resistance evaluation|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5625325	29033965	PrS	2	prepared plant materials and conducted insect resistance evaluation|initiated and coordinated the study, and analyzed the results|wrote the manuscript	prepared plant materials and conducted insect resistance evaluation	Performed the experiments	Investigation	YES
5625325	29033965	PrS	2	prepared plant materials and conducted insect resistance evaluation|initiated and coordinated the study, and analyzed the results|wrote the manuscript	initiated and coordinated the study, and analyzed the results	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Project administration	YES
5625325	29033965	PrS	2	prepared plant materials and conducted insect resistance evaluation|initiated and coordinated the study, and analyzed the results|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5625325	29033965	TY	2	prepared plant materials and conducted insect resistance evaluation	prepared plant materials and conducted insect resistance evaluation	Performed the experiments	Investigation	YES
5625325	29033965	XC	2	performed dna sequencing, and analyzed sequencing results|wrote the manuscript	performed dna sequencing, and analyzed sequencing results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5625325	29033965	XC	2	performed dna sequencing, and analyzed sequencing results|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5625325	29033965	XY	2	performed dna sequencing, and analyzed sequencing results	performed dna sequencing, and analyzed sequencing results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3662588	23663412	AMS	2	helped in the design of the experiments and as consultant	helped in the design of the experiments and as consultant	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3662588	23663412	CL	2	helped with the animal experiments and with the anesthesia, injections, imaging, necropsy, and tissue preparation	helped with the animal experiments and with the anesthesia, injections, imaging, necropsy, and tissue preparation	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
3662588	23663412	GZ	2	performed the tissue staining	performed the tissue staining	Performed the experiments	Investigation	YES
3662588	23663412	LJ	2	helped design the experiments, analyze and interpret data, and prepare the manuscript	helped design the experiments, analyze and interpret data, and prepare the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
3662588	23663412	MK	2	helped in the acquisition of data	helped in the acquisition of data	Performed the experiments	Investigation	YES
3662588	23663412	YT	2	helped design the experiments, prepared the tracers, and performed the experiments	helped design the experiments, prepared the tracers, and performed the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5445377	28545396	All authors	5	contributed to various aspects of this work (ordered by degree of contribution): conceived the study (NS	contributed to various aspects of this work (ordered by degree of contribution): conceived the study (NS	Conceived and designed the experiments	Conceptualization	YES
4409309	25910170	AGA	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409309	25910170	IMJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409309	25910170	IMJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409309	25910170	IMJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409309	25910170	JA	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4409309	25910170	JA	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409309	25910170	JLRA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409309	25910170	JLRA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409309	25910170	JLRA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409309	25910170	MSJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409309	25910170	MSJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409309	25910170	MSJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409309	25910170	MSJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5847219	28952037	All authors	2	have seen and approved the final version of the manuscript|have contributed substantially towards the conception, design or acquisition of data, and analysis or data interpretation or the drafting or revision of the manuscript	have seen and approved the final version of the manuscript	-	-	NO
5847219	28952037	All authors	2	have seen and approved the final version of the manuscript|have contributed substantially towards the conception, design or acquisition of data, and analysis or data interpretation or the drafting or revision of the manuscript	have contributed substantially towards the conception, design or acquisition of data, and analysis or data interpretation or the drafting or revision of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
3664572	23701960	All authors	2	contributed substantially to the scientific process leading to this manuscript	contributed substantially to the scientific process leading to this manuscript	-	-	NO
3664572	23701960	HI	2	performed the image analysis and simulation	performed the image analysis and simulation	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
3664572	23701960	NKa	2	participated in the study design and the data analysis	participated in the study design and the data analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
3664572	23701960	NKu	2	participated in the study design and the data analysis|performed the image analysis and simulation|drafted the manuscript	participated in the study design and the data analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
3664572	23701960	NKu	2	participated in the study design and the data analysis|performed the image analysis and simulation|drafted the manuscript	performed the image analysis and simulation	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
3664572	23701960	NKu	2	participated in the study design and the data analysis|performed the image analysis and simulation|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
3664572	23701960	TM	2	acquired data on the subjects	acquired data on the subjects	Performed the experiments	Investigation	YES
3664572	23701960	YM	2	participated in the study design and the data analysis|acquired data on the subjects	participated in the study design and the data analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
3664572	23701960	YM	2	participated in the study design and the data analysis|acquired data on the subjects	acquired data on the subjects	Performed the experiments	Investigation	YES
3664572	23701960	YN	2	participated in the study design and the data analysis	participated in the study design and the data analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
3664572	23701960	YS	2	acquired data on the subjects	acquired data on the subjects	Performed the experiments	Investigation	YES
3664572	23701960	YY	2	participated in the study design and the data analysis	participated in the study design and the data analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
3745988	23983646	Guangli Xu	2	contributed equally to this work	contributed equally to this work	-	-	NO
3745988	23983646	Hangxia Jin	2	contributed equally to this work	contributed equally to this work	-	-	NO
1764711	17225864	CR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1764711	17225864	CR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1764711	17225864	CR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1764711	17225864	CR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1764711	17225864	PS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1764711	17225864	PS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1764711	17225864	PS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5625327	29033954	CS	2	conceived of and wrote the manuscript	conceived of and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5625327	29033954	CZ	2	conceived of and wrote the manuscript	conceived of and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5625327	29033954	JY	2	conceived of and wrote the manuscript	conceived of and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5978714	29633564	AB	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5978714	29633564	KL	2	gave critical revisions	gave critical revisions	Wrote the paper	Writing - Review & Editing	YES
5978714	29633564	LD	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
3665493	23688107	CP	2	carried out the experimental treatments and imaging studies	carried out the experimental treatments and imaging studies	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
3665493	23688107	DH	2	conceived of the study and participated in its design and in the manuscript	conceived of the study and participated in its design and in the manuscript	Conceived and designed the experiments	Conceptualization|Methodology	YES
3665493	23688107	ED	2	carried out the development of the src orthotopic model	carried out the development of the src orthotopic model	Performed the experiments	Investigation|Methodology	YES
3665493	23688107	EMN	2	carried out the experimental treatments and imaging studies	carried out the experimental treatments and imaging studies	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
3665493	23688107	FG	2	carried out the development of the src orthotopic model	carried out the development of the src orthotopic model	Performed the experiments	Investigation|Methodology	YES
3665493	23688107	FR	2	conceived of the study and participated in its design and in the manuscript	conceived of the study and participated in its design and in the manuscript	Conceived and designed the experiments	Conceptualization|Methodology	YES
3665493	23688107	MFH	2	participated in the histology analysis	participated in the histology analysis	Performed the experiments	Investigation	YES
3665493	23688107	MMD	2	carried out the histology	carried out the histology	Performed the experiments	Investigation	YES
3665493	23688107	SB	2	carried out the experimental treatments and imaging studies	carried out the experimental treatments and imaging studies	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
4409310	25910005	AIHM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409310	25910005	AIHM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409310	25910005	AIHM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409310	25910005	AIHM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409310	25910005	DC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409310	25910005	DC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409310	25910005	DC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409310	25910005	DC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409310	25910005	HJ	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4409310	25910005	HJ	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409310	25910005	SY	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4409310	25910005	SY	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1764712	17225856	AP	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1764712	17225856	AP	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1764712	17225856	AS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1764712	17225856	AS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1764712	17225856	CH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1764712	17225856	CH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1764712	17225856	CH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1764712	17225856	CH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1764712	17225856	DB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1764712	17225856	DB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1764712	17225856	DB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1764712	17225856	JT	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1764712	17225856	KB	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1764712	17225856	KB	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1764712	17225856	KK	PLoS5	Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1764712	17225856	KK	PLoS5	Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1764712	17225856	KK	PLoS5	Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1764712	17225856	KK	PLoS5	Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1764712	17225856	MC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1764712	17225856	MO	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1764712	17225856	MO	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1764712	17225856	MO	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3665500	23651690	DMG	2	equally contributed to the making of this paper	equally contributed to the making of this paper	-	-	NO
3665500	23651690	RMS	2	equally contributed to the making of this paper	equally contributed to the making of this paper	-	-	NO
3665500	23651690	WJM	2	equally contributed to the making of this paper	equally contributed to the making of this paper	-	-	NO
5978738	29171180	All authors	2	contributed to writing and review, and all approved the final version	contributed to writing and review, and all approved the final version	Wrote the paper	Writing - Review & Editing	YES
5445414	28545453	DK	2	were responsible for the conception and design of the experiment|was the principal investigator for the study and provided edits for the final manuscript	were responsible for the conception and design of the experiment	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
5445414	28545453	DK	2	were responsible for the conception and design of the experiment|was the principal investigator for the study and provided edits for the final manuscript	was the principal investigator for the study and provided edits for the final manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Funding acquisition|Writing - Review & Editing	YES
5445414	28545453	FK	2	were responsible for the conception and design of the experiment|performed all experiments, analyses and manuscript preparation	were responsible for the conception and design of the experiment	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
5445414	28545453	FK	2	were responsible for the conception and design of the experiment|performed all experiments, analyses and manuscript preparation	performed all experiments, analyses and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4409311	25909381	CLE	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409311	25909381	CLE	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409311	25909381	CLE	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409311	25909381	CN	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409311	25909381	FL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409311	25909381	JC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409311	25909381	KL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409311	25909381	KL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409311	25909381	KL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409311	25909381	MG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409311	25909381	MGP	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409311	25909381	MGP	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409311	25909381	MGP	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409311	25909381	MKH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409311	25909381	MKH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409311	25909381	MKH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409311	25909381	MLD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409311	25909381	MLD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409311	25909381	MLD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409311	25909381	MLD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409311	25909381	SMT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409311	25909381	SMT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409311	25909381	SMT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409311	25909381	TEA	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409311	25909381	WEH	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5625568	29033964	MP	4	methodology review and editing was made by	methodology review and editing was made by	Performed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5625568	29033964	NH	4	methodology review and editing was made by	methodology review and editing was made by	Performed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5625568	29033964	VF	4	writing of original draft and Writing - review & editing was made by	writing of original draft and Writing - review & editing was made by	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3671201	23688063	AV	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
3671201	23688063	All authors	PLoS52	contributed to the design of the encdat study	contributed to the design of the encdat study	Conceived and designed the experiments	Methodology	YES
3671201	23688063	FN	PLoS52	recruited the subjects, interviewed the subjects about tobacco smoking habits and acquired spect data on the subjects	recruited the subjects, interviewed the subjects about tobacco smoking habits and acquired spect data on the subjects	Performed the experiments	Investigation	YES
3671201	23688063	GMK	PLoS52	recruited the subjects, interviewed the subjects about tobacco smoking habits and acquired spect data on the subjects	recruited the subjects, interviewed the subjects about tobacco smoking habits and acquired spect data on the subjects	Performed the experiments	Investigation	YES
3671201	23688063	GT	PLoS52	analyzed the data|drafted the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
3671201	23688063	GT	PLoS52	analyzed the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
3671201	23688063	JB	PLoS52	recruited the subjects, interviewed the subjects about tobacco smoking habits and acquired spect data on the subjects	recruited the subjects, interviewed the subjects about tobacco smoking habits and acquired spect data on the subjects	Performed the experiments	Investigation	YES
3671201	23688063	JCD	PLoS52	recruited the subjects, interviewed the subjects about tobacco smoking habits and acquired spect data on the subjects|analyzed the data	recruited the subjects, interviewed the subjects about tobacco smoking habits and acquired spect data on the subjects	Performed the experiments	Investigation	YES
3671201	23688063	JCD	PLoS52	recruited the subjects, interviewed the subjects about tobacco smoking habits and acquired spect data on the subjects|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
3671201	23688063	JD	PLoS52	recruited the subjects, interviewed the subjects about tobacco smoking habits and acquired spect data on the subjects	recruited the subjects, interviewed the subjects about tobacco smoking habits and acquired spect data on the subjects	Performed the experiments	Investigation	YES
3671201	23688063	KKH	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
3671201	23688063	KT	PLoS52	recruited the subjects, interviewed the subjects about tobacco smoking habits and acquired spect data on the subjects	recruited the subjects, interviewed the subjects about tobacco smoking habits and acquired spect data on the subjects	Performed the experiments	Investigation	YES
3671201	23688063	KVL	PLoS52	recruited the subjects, interviewed the subjects about tobacco smoking habits and acquired spect data on the subjects	recruited the subjects, interviewed the subjects about tobacco smoking habits and acquired spect data on the subjects	Performed the experiments	Investigation	YES
3671201	23688063	LHP	PLoS52	analyzed the data|drafted the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
3671201	23688063	LHP	PLoS52	analyzed the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
3671201	23688063	LTB	PLoS52	recruited the subjects, interviewed the subjects about tobacco smoking habits and acquired spect data on the subjects|analyzed the data	recruited the subjects, interviewed the subjects about tobacco smoking habits and acquired spect data on the subjects	Performed the experiments	Investigation	YES
3671201	23688063	LTB	PLoS52	recruited the subjects, interviewed the subjects about tobacco smoking habits and acquired spect data on the subjects|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
3671201	23688063	MP	PLoS52	recruited the subjects, interviewed the subjects about tobacco smoking habits and acquired spect data on the subjects	recruited the subjects, interviewed the subjects about tobacco smoking habits and acquired spect data on the subjects	Performed the experiments	Investigation	YES
3671201	23688063	MZ	PLoS52	recruited the subjects, interviewed the subjects about tobacco smoking habits and acquired spect data on the subjects|analyzed the data	recruited the subjects, interviewed the subjects about tobacco smoking habits and acquired spect data on the subjects	Performed the experiments	Investigation	YES
3671201	23688063	MZ	PLoS52	recruited the subjects, interviewed the subjects about tobacco smoking habits and acquired spect data on the subjects|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
3671201	23688063	OLK	PLoS52	recruited the subjects, interviewed the subjects about tobacco smoking habits and acquired spect data on the subjects	recruited the subjects, interviewed the subjects about tobacco smoking habits and acquired spect data on the subjects	Performed the experiments	Investigation	YES
3671201	23688063	OS	PLoS52	recruited the subjects, interviewed the subjects about tobacco smoking habits and acquired spect data on the subjects	recruited the subjects, interviewed the subjects about tobacco smoking habits and acquired spect data on the subjects	Performed the experiments	Investigation	YES
3671201	23688063	PSJ	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
3671201	23688063	SA	PLoS52	recruited the subjects, interviewed the subjects about tobacco smoking habits and acquired spect data on the subjects	recruited the subjects, interviewed the subjects about tobacco smoking habits and acquired spect data on the subjects	Performed the experiments	Investigation	YES
3671201	23688063	TS	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
3671201	23688063	TVB	PLoS52	recruited the subjects, interviewed the subjects about tobacco smoking habits and acquired spect data on the subjects	recruited the subjects, interviewed the subjects about tobacco smoking habits and acquired spect data on the subjects	Performed the experiments	Investigation	YES
3671201	23688063	The authors	PLoS52	recruited the subjects, interviewed the subjects about tobacco smoking habits and acquired spect data on the subjects	recruited the subjects, interviewed the subjects about tobacco smoking habits and acquired spect data on the subjects	Performed the experiments	Investigation	YES
4539210	26339613	Andrey Alexeyenko	2	conceived the study and wrote the paper|performed data analysis	conceived the study and wrote the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4539210	26339613	Andrey Alexeyenko	2	conceived the study and wrote the paper|performed data analysis	performed data analysis	Analyzed the data	Formal analysis	YES
4539210	26339613	Woojoo Lee	2	conceived the study and wrote the paper|performed data analysis	conceived the study and wrote the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4539210	26339613	Woojoo Lee	2	conceived the study and wrote the paper|performed data analysis	performed data analysis	Analyzed the data	Formal analysis	YES
4539210	26339613	Yudi Pawitan	2	conceived the study and wrote the paper	conceived the study and wrote the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
1764713	17225857	RV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1764713	17225857	RV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1764713	17225857	RV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1764713	17225857	RV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1764713	17225857	RV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1764713	17225857	SB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1764713	17225857	SB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1764713	17225857	SB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5980503	29851436	All authors	2	critically reviewed and approved the current version of the manuscript	critically reviewed and approved the current version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5980503	29851436	BT	2	supervised data collection at the ugandan sites	supervised data collection at the ugandan sites	Performed the experiments	Investigation|Supervision	YES
5980503	29851436	CLC	2	provided feedback on emerging findings from the qualitative study and reviewed and provided comments on a preliminary draft of the manuscript	provided feedback on emerging findings from the qualitative study and reviewed and provided comments on a preliminary draft of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5980503	29851436	ENJ	2	supervised data collection at the ugandan sites	supervised data collection at the ugandan sites	Performed the experiments	Investigation|Supervision	YES
5980503	29851436	ETK	2	supervised data collection at the ugandan sites	supervised data collection at the ugandan sites	Performed the experiments	Investigation|Supervision	YES
5980503	29851436	JMB	2	provided feedback on emerging findings from the qualitative study and reviewed and provided comments on a preliminary draft of the manuscript	provided feedback on emerging findings from the qualitative study and reviewed and provided comments on a preliminary draft of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5980503	29851436	MAW	2	designed the qualitative research	designed the qualitative research	Conceived and designed the experiments	Methodology	YES
5980503	29851436	NCW	2	designed the qualitative research|led the data analytic process and wrote and revised the manuscript	designed the qualitative research	Conceived and designed the experiments	Methodology	YES
5980503	29851436	NCW	2	designed the qualitative research|led the data analytic process and wrote and revised the manuscript	led the data analytic process and wrote and revised the manuscript	Analyzed the data|Wrote the paper	Data curation|Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5980503	29851436	RAH	2	provided feedback on emerging findings from the qualitative study and reviewed and provided comments on a preliminary draft of the manuscript	provided feedback on emerging findings from the qualitative study and reviewed and provided comments on a preliminary draft of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5980503	29851436	SBA	2	supervised data collection at the ugandan sites	supervised data collection at the ugandan sites	Performed the experiments	Investigation|Supervision	YES
5980503	29851436	TRM	2	supervised data collection at the ugandan sites	supervised data collection at the ugandan sites	Performed the experiments	Investigation|Supervision	YES
3680030	23738809	AHV	2	participated in the design of the study and evaluation and helped draft the manuscript	participated in the design of the study and evaluation and helped draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3680030	23738809	JH	2	participated in the design of the study and coordination and helped draft the manuscript	participated in the design of the study and coordination and helped draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft	YES
3680030	23738809	MC	2	conceived the study, participated in its design and coordination, carried out measurements, data processing and evaluation, and drafted the manuscript	conceived the study, participated in its design and coordination, carried out measurements, data processing and evaluation, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Data curation|Investigation|Methodology|Project administration|Writing - Original Draft	YES
3680030	23738809	TK	2	conceived the study, participated in its design, coordination and evaluation, and drafted the manuscript	conceived the study, participated in its design, coordination and evaluation, and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
5445440	28545405	AT	2	guided and performed biochemical and nir analysis of stem samples|have edited the manuscript	guided and performed biochemical and nir analysis of stem samples	Performed the experiments	Investigation|Supervision	YES
5445440	28545405	AT	2	guided and performed biochemical and nir analysis of stem samples|have edited the manuscript	have edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5445440	28545405	CAM	2	mapped the traits on the genetic map	mapped the traits on the genetic map	Performed the experiments	Investigation	YES
5445440	28545405	CLAK	2	performed dna extractions|guided the sequencing experiment and analyzed and transformed sequence data into short-sequence haplotype markers|have edited the manuscript	performed dna extractions	Performed the experiments	Investigation	YES
5445440	28545405	CLAK	2	performed dna extractions|guided the sequencing experiment and analyzed and transformed sequence data into short-sequence haplotype markers|have edited the manuscript	guided the sequencing experiment and analyzed and transformed sequence data into short-sequence haplotype markers	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Supervision	YES
5445440	28545405	CLAK	2	performed dna extractions|guided the sequencing experiment and analyzed and transformed sequence data into short-sequence haplotype markers|have edited the manuscript	have edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5445440	28545405	EIS	2	guided the sequencing experiment and analyzed and transformed sequence data into short-sequence haplotype markers|have edited the manuscript	guided the sequencing experiment and analyzed and transformed sequence data into short-sequence haplotype markers	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Supervision	YES
5445440	28545405	EIS	2	guided the sequencing experiment and analyzed and transformed sequence data into short-sequence haplotype markers|have edited the manuscript	have edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5445440	28545405	LDG	2	guided and performed biochemical and nir analysis of stem samples	guided and performed biochemical and nir analysis of stem samples	Performed the experiments	Investigation|Supervision	YES
5445440	28545405	LM	2	have edited the manuscript	have edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5445440	28545405	LMT	2	created the mapping population and designed the field experiment|guided and performed biochemical and nir analysis of stem samples	created the mapping population and designed the field experiment	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5445440	28545405	LMT	2	created the mapping population and designed the field experiment|guided and performed biochemical and nir analysis of stem samples	guided and performed biochemical and nir analysis of stem samples	Performed the experiments	Investigation|Supervision	YES
5445440	28545405	OD	2	created the mapping population and designed the field experiment|created the genetic map|mapped the traits on the genetic map|have edited the manuscript	created the mapping population and designed the field experiment	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5445440	28545405	OD	2	created the mapping population and designed the field experiment|created the genetic map|mapped the traits on the genetic map|have edited the manuscript	created the genetic map	Performed the experiments	Investigation	YES
5445440	28545405	OD	2	created the mapping population and designed the field experiment|created the genetic map|mapped the traits on the genetic map|have edited the manuscript	mapped the traits on the genetic map	Performed the experiments	Investigation	YES
5445440	28545405	OD	2	created the mapping population and designed the field experiment|created the genetic map|mapped the traits on the genetic map|have edited the manuscript	have edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5445440	28545405	RGFV	2	have edited the manuscript	have edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5445440	28545405	SJMM	2	guided and performed biochemical and nir analysis of stem samples	guided and performed biochemical and nir analysis of stem samples	Performed the experiments	Investigation|Supervision	YES
5445440	28545405	TvdW	2	created the genetic map|guided and performed biochemical and nir analysis of stem samples|mapped the traits on the genetic map|wrote the manuscript, with contributions from the coauthors in the methods section	created the genetic map	Performed the experiments	Investigation	YES
5445440	28545405	TvdW	2	created the genetic map|guided and performed biochemical and nir analysis of stem samples|mapped the traits on the genetic map|wrote the manuscript, with contributions from the coauthors in the methods section	guided and performed biochemical and nir analysis of stem samples	Performed the experiments	Investigation|Supervision	YES
5445440	28545405	TvdW	2	created the genetic map|guided and performed biochemical and nir analysis of stem samples|mapped the traits on the genetic map|wrote the manuscript, with contributions from the coauthors in the methods section	mapped the traits on the genetic map	Performed the experiments	Investigation	YES
5445440	28545405	TvdW	2	created the genetic map|guided and performed biochemical and nir analysis of stem samples|mapped the traits on the genetic map|wrote the manuscript, with contributions from the coauthors in the methods section	wrote the manuscript, with contributions from the coauthors in the methods section	Performed the experiments|Wrote the paper	Writing - Original Draft	YES
5625571	29033961	AF	2	implemented and tested the software	implemented and tested the software	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5625571	29033961	All authors	2	contributed to text and figures of the manuscript and approved the final manuscript	contributed to text and figures of the manuscript and approved the final manuscript	Wrote the paper	Visualization|Writing - Original Draft|Writing - Review & Editing	YES
5625571	29033961	CB	2	implemented and tested the software|performed all lab experiments	implemented and tested the software	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5625571	29033961	CB	2	implemented and tested the software|performed all lab experiments	performed all lab experiments	Performed the experiments	Investigation	YES
5625571	29033961	FF	2	designed the study|drafted the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5625571	29033961	FF	2	designed the study|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5625571	29033961	HS	2	designed the study|implemented and tested the software|drafted the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5625571	29033961	HS	2	designed the study|implemented and tested the software|drafted the manuscript	implemented and tested the software	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5625571	29033961	HS	2	designed the study|implemented and tested the software|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5625571	29033961	MM	2	designed the study|drafted the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5625571	29033961	MM	2	designed the study|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5625571	29033961	PE	2	implemented and tested the software|performed all lab experiments	implemented and tested the software	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5625571	29033961	PE	2	implemented and tested the software|performed all lab experiments	performed all lab experiments	Performed the experiments	Investigation	YES
5625571	29033961	The authors	2	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	Performed the experiments	Investigation	YES
4409313	25909949	KY	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409313	25909949	KY	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409313	25909949	ST	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409313	25909949	ST	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409313	25909949	ST	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409313	25909949	TB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409313	25909949	WY	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409313	25909949	WY	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409313	25909949	WY	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5980617	29852062	C.A-Y	PLoS52	analysed the data|wrote the paper	analysed the data	Analyzed the data	Formal analysis	YES
5980617	29852062	C.A-Y	PLoS52	analysed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5980617	29852062	D.K.	PLoS52	performed the research	performed the research	Performed the experiments	Investigation	YES
5980617	29852062	G.A.	PLoS52	performed the research	performed the research	Performed the experiments	Investigation	YES
5980617	29852062	J.M.	PLoS52	designed the research study	designed the research study	Conceived and designed the experiments	Methodology	YES
5980617	29852062	K.M.	PLoS52	performed the research	performed the research	Performed the experiments	Investigation	YES
5980617	29852062	L.V.	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5980617	29852062	M.H.	PLoS52	analysed the data|wrote the paper	analysed the data	Analyzed the data	Formal analysis	YES
5980617	29852062	M.H.	PLoS52	analysed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5980617	29852062	M.I.	PLoS52	designed the research study|performed the research|analysed the data|wrote the paper	designed the research study	Conceived and designed the experiments	Methodology	YES
5980617	29852062	M.I.	PLoS52	designed the research study|performed the research|analysed the data|wrote the paper	performed the research	Performed the experiments	Investigation	YES
5980617	29852062	M.I.	PLoS52	designed the research study|performed the research|analysed the data|wrote the paper	analysed the data	Analyzed the data	Formal analysis	YES
5980617	29852062	M.I.	PLoS52	designed the research study|performed the research|analysed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5980617	29852062	M.L.	PLoS52	performed the research	performed the research	Performed the experiments	Investigation	YES
5980617	29852062	M.S.	PLoS52	performed the research	performed the research	Performed the experiments	Investigation	YES
5980617	29852062	O.B.	PLoS52	performed the research	performed the research	Performed the experiments	Investigation	YES
5980617	29852062	P.J-P	PLoS52	designed the research study	designed the research study	Conceived and designed the experiments	Methodology	YES
5980617	29852062	R.S.	PLoS52	designed the research study|performed the research|analysed the data|wrote the paper	designed the research study	Conceived and designed the experiments	Methodology	YES
5980617	29852062	R.S.	PLoS52	designed the research study|performed the research|analysed the data|wrote the paper	performed the research	Performed the experiments	Investigation	YES
5980617	29852062	R.S.	PLoS52	designed the research study|performed the research|analysed the data|wrote the paper	analysed the data	Analyzed the data	Formal analysis	YES
5980617	29852062	R.S.	PLoS52	designed the research study|performed the research|analysed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5980617	29852062	S.L.	PLoS52	designed the research study|wrote the paper	designed the research study	Conceived and designed the experiments	Methodology	YES
5980617	29852062	S.L.	PLoS52	designed the research study|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5980617	29852062	S.M.	PLoS52	performed the research	performed the research	Performed the experiments	Investigation	YES
5980617	29852062	X.Y.	PLoS52	performed the research	performed the research	Performed the experiments	Investigation	YES
3680321	23738774	AW	2	participated in the review and critique on the manuscript and data collection	participated in the review and critique on the manuscript and data collection	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
3680321	23738774	CVMV	2	participated in the review and critique on the manuscript	participated in the review and critique on the manuscript	Wrote the paper	Writing - Review & Editing	YES
3680321	23738774	HWB	2	participated in the review and critique on the manuscript and data collection	participated in the review and critique on the manuscript and data collection	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
3680321	23738774	JB	2	participated in the research project conception, organization, and execution, data collection, and review and critique on the statistical analysis and manuscript	participated in the research project conception, organization, and execution, data collection, and review and critique on the statistical analysis and manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Project administration|Writing - Review & Editing	YES
3680321	23738774	RMADB	2	conceived of the research project	conceived of the research project	Conceived and designed the experiments	Conceptualization	YES
3680321	23738774	SRS	2	participated in the research project organization and execution and in the design and execution of the statistical analysis, data collection, and writing of the first draft of the manuscript	participated in the research project organization and execution and in the design and execution of the statistical analysis, data collection, and writing of the first draft of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Project administration|Writing - Original Draft	YES
1764714	17225865	JW	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1764714	17225865	JW	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1764714	17225865	LX	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1764714	17225865	LX	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1764714	17225865	MW	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1764714	17225865	MW	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1764714	17225865	MW	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1764714	17225865	TT	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1764714	17225865	WW	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1764714	17225865	WW	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1764714	17225865	YS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1764714	17225865	ZZ	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4258698	25489352	B Gauvain	2	participated to conception and design of the study, revision and final approval of the article	participated to conception and design of the study, revision and final approval of the article	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
4258698	25489352	B Verlhac	2	take responsibility for conception and design of the study, acquisition and analysis of data, drafting and final version of this article	take responsibility for conception and design of the study, acquisition and analysis of data, drafting and final version of this article	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4258698	25489352	C Jeandel	2	participated to conception and design of the study, revision and final approval of the article	participated to conception and design of the study, revision and final approval of the article	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
4258698	25489352	E Maheu	2	take responsibility for conception and design of the study, acquisition and analysis of data, drafting and final version of this article	take responsibility for conception and design of the study, acquisition and analysis of data, drafting and final version of this article	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4258698	25489352	JL	2	take responsibility for conception and design of the study, acquisition and analysis of data, drafting and final version of this article	take responsibility for conception and design of the study, acquisition and analysis of data, drafting and final version of this article	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4258698	25489352	Le Quintrec	2	take responsibility for conception and design of the study, acquisition and analysis of data, drafting and final version of this article	take responsibility for conception and design of the study, acquisition and analysis of data, drafting and final version of this article	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5445459	28545446	AA	PLoS52	participated in the study design	participated in the study design	Conceived and designed the experiments	Methodology	YES
5445459	28545446	All the authors	PLoS52	have contributed to the manuscript and approved the final version	have contributed to the manuscript and approved the final version	-	-	NO
5445459	28545446	BB	PLoS52	analyzed the data|drafted the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5445459	28545446	BB	PLoS52	analyzed the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5445459	28545446	BW	PLoS52	were responsible for sampling	were responsible for sampling	Performed the experiments	Investigation	YES
5445459	28545446	DAC	PLoS52	participated in the study design|were responsible for the laboratory analyses	participated in the study design	Conceived and designed the experiments	Methodology	YES
5445459	28545446	DAC	PLoS52	participated in the study design|were responsible for the laboratory analyses	were responsible for the laboratory analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5445459	28545446	DB	PLoS52	were responsible for sampling	were responsible for sampling	Performed the experiments	Investigation	YES
5445459	28545446	GKB	PLoS52	were responsible for sampling|were responsible for the laboratory analyses|analyzed the data|drafted the manuscript	were responsible for sampling	Performed the experiments	Investigation	YES
5445459	28545446	GKB	PLoS52	were responsible for sampling|were responsible for the laboratory analyses|analyzed the data|drafted the manuscript	were responsible for the laboratory analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5445459	28545446	GKB	PLoS52	were responsible for sampling|were responsible for the laboratory analyses|analyzed the data|drafted the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5445459	28545446	GKB	PLoS52	were responsible for sampling|were responsible for the laboratory analyses|analyzed the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5445459	28545446	OBB	PLoS52	analyzed the data|was responsible for the statistical and phylogenetic analyses	analyzed the data	Analyzed the data	Formal analysis	YES
5445459	28545446	OBB	PLoS52	analyzed the data|was responsible for the statistical and phylogenetic analyses	was responsible for the statistical and phylogenetic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5445459	28545446	PK	PLoS52	participated in the study design|were responsible for sampling	participated in the study design	Conceived and designed the experiments	Methodology	YES
5445459	28545446	PK	PLoS52	participated in the study design|were responsible for sampling	were responsible for sampling	Performed the experiments	Investigation	YES
5987811	29870128	RK	2	drafted and finalized the manuscript	drafted and finalized the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5626847	29033971	All of the authors	2	have read and approved the final manuscript	have read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5626847	29033971	GL	2	prepared the plant materials	prepared the plant materials	Performed the experiments	Investigation	YES
5626847	29033971	HW	2	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5626847	29033971	JS	2	contributed to the construction of molecular genetic map	contributed to the construction of molecular genetic map	Performed the experiments	Investigation	YES
5626847	29033971	JW	2	performed the data analysis and wrote the main manuscript text	performed the data analysis and wrote the main manuscript text	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5626847	29033971	XD	2	designed and managed the experiments	designed and managed the experiments	Conceived and designed the experiments	Methodology	YES
5626847	29033971	XW	2	prepared the plant materials	prepared the plant materials	Performed the experiments	Investigation	YES
4409314	25910229	ABS	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409314	25910229	ABS	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409314	25910229	BCL	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409314	25910229	BCL	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409314	25910229	DEM	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409314	25910229	DEM	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409314	25910229	KKA	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409314	25910229	KKA	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409314	25910229	KMH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409314	25910229	KMH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409314	25910229	KMH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409314	25910229	LS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409314	25910229	LS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409314	25910229	LS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409314	25910229	MEF	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409314	25910229	MEF	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409314	25910229	MEF	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409314	25910229	MGS	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409314	25910229	MGS	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409314	25910229	MLA	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409314	25910229	MLA	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409314	25910229	NTS	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409314	25910229	NTS	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409314	25910229	SHJ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409314	25910229	SHJ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409314	25910229	SHJ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409314	25910229	SIJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409314	25910229	SIJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409314	25910229	SIJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409314	25910229	SIJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409314	25910229	SIJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409314	25910229	WCP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409314	25910229	WCP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409314	25910229	WCP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409314	25910229	ZCH	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409314	25910229	ZCH	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3683333	23758896	CM	2	were responsible for the radiochemistry section	were responsible for the radiochemistry section	-	-	NO
3683333	23758896	DRF	2	participated in the acquisition and analysis of human and monkey data	participated in the acquisition and analysis of human and monkey data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3683333	23758896	EN	2	performed in vitro analyses	performed in vitro analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3683333	23758896	ES	2	performed in vitro analyses	performed in vitro analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3683333	23758896	JSL	2	participated in the acquisition and analysis of human and monkey data	participated in the acquisition and analysis of human and monkey data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3683333	23758896	JT	2	conceived the study and participated in its design and coordination	conceived the study and participated in its design and coordination	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
3683333	23758896	PZF	2	participated in the acquisition and analysis of human and monkey data	participated in the acquisition and analysis of human and monkey data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3683333	23758896	RBI	2	conceived the study and participated in its design and coordination	conceived the study and participated in its design and coordination	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
3683333	23758896	RLG	2	participated in the acquisition and analysis of human and monkey data	participated in the acquisition and analysis of human and monkey data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3683333	23758896	SSZ	2	performed blood analyses	performed blood analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3683333	23758896	VNB	2	performed in vitro analyses	performed in vitro analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3683333	23758896	VWP	2	were responsible for the radiochemistry section	were responsible for the radiochemistry section	-	-	NO
1764715	17225858	AS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1764715	17225858	AS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1764715	17225858	AS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1764715	17225858	DC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Assisted in manuscript preparation	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1764715	17225858	DC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Assisted in manuscript preparation	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1764715	17225858	DC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Assisted in manuscript preparation	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1764715	17225858	DC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Assisted in manuscript preparation	Assisted in manuscript preparation	Wrote the paper	Writing - Original Draft	YES
1764715	17225858	EV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Assisted in manuscript preparation	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1764715	17225858	EV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Assisted in manuscript preparation	Performed the experiments	Performed the experiments	Investigation	YES
1764715	17225858	EV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Assisted in manuscript preparation	Analyzed the data	Analyzed the data	Formal analysis	YES
1764715	17225858	EV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Assisted in manuscript preparation	Assisted in manuscript preparation	Wrote the paper	Writing - Original Draft	YES
1764715	17225858	L-CL	PLoS5	Assisted in manuscript preparation	Assisted in manuscript preparation	Wrote the paper	Writing - Original Draft	YES
1764715	17225858	LL	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1764715	17225858	LL	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1764715	17225858	YW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5445461	28545404	DN	2	designed the study and performed mathematical analysis|wrote the manuscript	designed the study and performed mathematical analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5445461	28545404	DN	2	designed the study and performed mathematical analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5445461	28545404	SY	2	performed simulation study and analyzed rna seq data|wrote the manuscript	performed simulation study and analyzed rna seq data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5445461	28545404	SY	2	performed simulation study and analyzed rna seq data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5989783	29873885	All	2	authors contributed to the interpretation of results, contributed technical expertise, commented on the drafts, and approved the final version	authors contributed to the interpretation of results, contributed technical expertise, commented on the drafts, and approved the final version	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5989783	29873885	KJL	2	extracted the data and performed the analysis	extracted the data and performed the analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5989783	29873885	MCB	2	designed and supervised the study and provided technical guidance|authors contributed to the interpretation of results, contributed technical expertise, commented on the drafts, and approved the final version	designed and supervised the study and provided technical guidance	Conceived and designed the experiments	Methodology|Supervision	YES
5989783	29873885	MCB	2	designed and supervised the study and provided technical guidance|authors contributed to the interpretation of results, contributed technical expertise, commented on the drafts, and approved the final version	authors contributed to the interpretation of results, contributed technical expertise, commented on the drafts, and approved the final version	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5989783	29873885	MMR	2	extracted the data and performed the analysis|authors contributed to the interpretation of results, contributed technical expertise, commented on the drafts, and approved the final version	extracted the data and performed the analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5989783	29873885	MMR	2	extracted the data and performed the analysis|authors contributed to the interpretation of results, contributed technical expertise, commented on the drafts, and approved the final version	authors contributed to the interpretation of results, contributed technical expertise, commented on the drafts, and approved the final version	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3686612	23731770	CCL	2	participated in the concept, design, and analysis of the study	participated in the concept, design, and analysis of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3686612	23731770	CRD	2	participated in the concept, design, and analysis of the study	participated in the concept, design, and analysis of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3686612	23731770	EMB	2	participated in radiotracer development, formulation, and quality assurance	participated in radiotracer development, formulation, and quality assurance	Conceived and designed the experiments|Performed the experiments	Conceptualization|Validation	YES
3686612	23731770	HS	2	participated in the concept, design, and analysis of the study	participated in the concept, design, and analysis of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3686612	23731770	JAOD	2	participated in the concept, design, and analysis of the study|acquired the data|drafted the manuscript	participated in the concept, design, and analysis of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3686612	23731770	JAOD	2	participated in the concept, design, and analysis of the study|acquired the data|drafted the manuscript	acquired the data	Performed the experiments	Investigation	YES
3686612	23731770	JAOD	2	participated in the concept, design, and analysis of the study|acquired the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
3686612	23731770	JAR	2	were responsible for primary clinical management and patient accrual|drafted the manuscript	were responsible for primary clinical management and patient accrual	Performed the experiments	Investigation	YES
3686612	23731770	JAR	2	were responsible for primary clinical management and patient accrual|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
3686612	23731770	JGG	2	participated in the concept, design, and analysis of the study|were responsible for primary clinical management and patient accrual	participated in the concept, design, and analysis of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3686612	23731770	JGG	2	participated in the concept, design, and analysis of the study|were responsible for primary clinical management and patient accrual	were responsible for primary clinical management and patient accrual	Performed the experiments	Investigation	YES
3686612	23731770	JLH	2	participated in the concept, design, and analysis of the study|acquired the data	participated in the concept, design, and analysis of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3686612	23731770	JLH	2	participated in the concept, design, and analysis of the study|acquired the data	acquired the data	Performed the experiments	Investigation	YES
3686612	23731770	NYL	2	participated in the concept, design, and analysis of the study|were responsible for primary clinical management and patient accrual	participated in the concept, design, and analysis of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3686612	23731770	NYL	2	participated in the concept, design, and analysis of the study|were responsible for primary clinical management and patient accrual	were responsible for primary clinical management and patient accrual	Performed the experiments	Investigation	YES
3686612	23731770	PBZ	2	participated in the concept, design, and analysis of the study|acquired the data	participated in the concept, design, and analysis of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3686612	23731770	PBZ	2	participated in the concept, design, and analysis of the study|acquired the data	acquired the data	Performed the experiments	Investigation	YES
3686612	23731770	SALK	2	were responsible for primary clinical management and patient accrual	were responsible for primary clinical management and patient accrual	Performed the experiments	Investigation	YES
3686612	23731770	SC	2	participated in radiotracer development, formulation, and quality assurance	participated in radiotracer development, formulation, and quality assurance	Conceived and designed the experiments|Performed the experiments	Conceptualization|Validation	YES
3686612	23731770	SDC	2	acquired the data	acquired the data	Performed the experiments	Investigation	YES
3686612	23731770	TL	2	were responsible for primary clinical management and patient accrual	were responsible for primary clinical management and patient accrual	Performed the experiments	Investigation	YES
5626848	29033969	BN	7	Contributed in conception and design, analysis, interpretation of data; drafting and revising content; final approval of the version to be published; agreement to be accountable for all aspects of the work	Contributed in conception and design, analysis, interpretation of data; drafting and revising content; final approval of the version to be published; agreement to be accountable for all aspects of the work	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Resources|Writing - Original Draft	YES
5626848	29033969	BR	7	Contributed in analysis, interpretation of data; revising content; final approval of the version to be published; agreement to be accountable for all aspects of the work	Contributed in analysis, interpretation of data; revising content; final approval of the version to be published; agreement to be accountable for all aspects of the work	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5626848	29033969	MS	7	Contributed in conception and design, interpretation of data; drafting and revising content; final approval of the version to be published; agreement to be accountable for all aspects of the work	Contributed in conception and design, interpretation of data; drafting and revising content; final approval of the version to be published; agreement to be accountable for all aspects of the work	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Resources|Writing - Original Draft	YES
5626848	29033969	SB	7	Contributed in conception, analysis, interpretation of data; drafting and revising content; final approval of the version to be published; agreement to be accountable for all aspects of the work	Contributed in conception, analysis, interpretation of data; drafting and revising content; final approval of the version to be published; agreement to be accountable for all aspects of the work	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Resources|Writing - Original Draft	YES
5626848	29033969	SN	7	Contributed in conception, analysis, interpretation of data; drafting and revising content; final approval of the version to be published; agreement to be accountable for all aspects of the work	Contributed in conception, analysis, interpretation of data; drafting and revising content; final approval of the version to be published; agreement to be accountable for all aspects of the work	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Resources|Writing - Original Draft	YES
4409315	25909895	CW	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409315	25909895	FT	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409315	25909895	FT	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409315	25909895	JL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409315	25909895	JZ	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409315	25909895	LZ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409315	25909895	NL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409315	25909895	X. Wan	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409315	25909895	X. Wang	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409315	25909895	XG	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409315	25909895	XG	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409315	25909895	XG	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1764717	17225859	FZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1764717	17225859	FZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1764717	17225859	FZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1764717	17225859	FZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1764717	17225859	JH	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1764717	17225859	JH	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1764717	17225859	MJ	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1764717	17225859	RB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1764717	17225859	RB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1764717	17225859	RB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1764717	17225859	SZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5445492	28545447	All authors	PLoS52	analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
5445492	28545447	EB	PLoS52	conceived and coordinated the study|carried out the in silico element detection and performed the clustering and phylogenetic analyses|carried out the chs annotations and drafted the paper	conceived and coordinated the study	Conceived and designed the experiments	Conceptualization|Project administration	YES
5445492	28545447	EB	PLoS52	conceived and coordinated the study|carried out the in silico element detection and performed the clustering and phylogenetic analyses|carried out the chs annotations and drafted the paper	carried out the in silico element detection and performed the clustering and phylogenetic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5445492	28545447	EB	PLoS52	conceived and coordinated the study|carried out the in silico element detection and performed the clustering and phylogenetic analyses|carried out the chs annotations and drafted the paper	carried out the chs annotations and drafted the paper	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Formal analysis|Investigation|Writing - Original Draft	YES
5445492	28545447	MP	PLoS52	carried out the in silico element detection and performed the clustering and phylogenetic analyses|carried out the chs annotations and drafted the paper	carried out the in silico element detection and performed the clustering and phylogenetic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5445492	28545447	MP	PLoS52	carried out the in silico element detection and performed the clustering and phylogenetic analyses|carried out the chs annotations and drafted the paper	carried out the chs annotations and drafted the paper	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Formal analysis|Investigation|Writing - Original Draft	YES
5445492	28545447	TD	PLoS52	carried out the in silico element detection and performed the clustering and phylogenetic analyses	carried out the in silico element detection and performed the clustering and phylogenetic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5991587	29878719	Both authors	2	contributed equally to this work	contributed equally to this work	-	-	NO
5991587	29878719	CJH	2	conceptualized the viewpoint|contributed equally to the first draft and subsequent revisions|performed the literature search	conceptualized the viewpoint	Conceived and designed the experiments	Conceptualization	YES
5991587	29878719	CJH	2	conceptualized the viewpoint|contributed equally to the first draft and subsequent revisions|performed the literature search	contributed equally to the first draft and subsequent revisions	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5991587	29878719	CJH	2	conceptualized the viewpoint|contributed equally to the first draft and subsequent revisions|performed the literature search	performed the literature search	Performed the experiments	Formal analysis|Investigation	YES
5991587	29878719	DTN	2	conceptualized the viewpoint|contributed equally to the first draft and subsequent revisions	conceptualized the viewpoint	Conceived and designed the experiments	Conceptualization	YES
5991587	29878719	DTN	2	conceptualized the viewpoint|contributed equally to the first draft and subsequent revisions	contributed equally to the first draft and subsequent revisions	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4409316	25909480	AMD	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409316	25909480	APS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409316	25909480	BPAS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409316	25909480	CLS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409316	25909480	CMF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409316	25909480	CMF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409316	25909480	CMF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409316	25909480	DFTS	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409316	25909480	DFTS	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409316	25909480	JAFS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409316	25909480	KPSF	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409316	25909480	MTG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409316	25909480	RAMF	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409316	25909480	RAP	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409316	25909480	SKB	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
3689076	23758882	AR	2	participated in the design of the study and revised the manuscript|participated in the immunohistochemical analysis	participated in the design of the study and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
3689076	23758882	AR	2	participated in the design of the study and revised the manuscript|participated in the immunohistochemical analysis	participated in the immunohistochemical analysis	Performed the experiments	Investigation	YES
3689076	23758882	CT	2	data analysis and helped in drafting the manuscript	data analysis and helped in drafting the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3689076	23758882	KB	2	conceived the study, participated in its design and coordination, and revised the manuscript	conceived the study, participated in its design and coordination, and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Review & Editing	YES
3689076	23758882	PTM	2	conceived the study, participated in its design and coordination, and revised the manuscript	conceived the study, participated in its design and coordination, and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Review & Editing	YES
3689076	23758882	RKT	2	participated in the design of the study and revised the manuscript	participated in the design of the study and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
3689076	23758882	SB	2	did the animal work, tissue processing, and morphometric analyses, participated in designing the study, and drafted the manuscript	did the animal work, tissue processing, and morphometric analyses, participated in designing the study, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
3747400	23983642	Jen-Yang Tang	2	made equal contributions to this work	made equal contributions to this work	-	-	NO
3747400	23983642	Ping-Ho Chen	2	made equal contributions to this work	made equal contributions to this work	-	-	NO
5993164	29883052	All authors	2	were involved in manuscript revisions and approved the final version of the article for submission	were involved in manuscript revisions and approved the final version of the article for submission	Wrote the paper	Writing - Review & Editing	YES
5993164	29883052	JJO	2	developed the mathematical model, conducted all simulations, and wrote the first draft of the paper	developed the mathematical model, conducted all simulations, and wrote the first draft of the paper	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5993164	29883052	JWE	2	developed the mathematical model, conducted all simulations, and wrote the first draft of the paper	developed the mathematical model, conducted all simulations, and wrote the first draft of the paper	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5993164	29883052	JWH	2	oversaw the creation and analysis of the data, and provided substantial intellectual contributions on model development and interpretation of data	oversaw the creation and analysis of the data, and provided substantial intellectual contributions on model development and interpretation of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Methodology|Resources|Supervision	YES
5993164	29883052	PB	2	oversaw the creation and analysis of the data, and provided substantial intellectual contributions on model development and interpretation of data	oversaw the creation and analysis of the data, and provided substantial intellectual contributions on model development and interpretation of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Methodology|Resources|Supervision	YES
5993164	29883052	TBH	2	developed the mathematical model, conducted all simulations, and wrote the first draft of the paper	developed the mathematical model, conducted all simulations, and wrote the first draft of the paper	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
544599	15610565	DL	2	amended and improved the design of the study	amended and improved the design of the study	Conceived and designed the experiments	Methodology	YES
544599	15610565	HJA	2	conceived of this study, carried out the tests, and drafted the manuscript	conceived of this study, carried out the tests, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
544599	15610565	JB	2	participated in the design of the study and drafted the manuscript	participated in the design of the study and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
544599	15610565	KWL	2	amended and improved the design of the study	amended and improved the design of the study	Conceived and designed the experiments	Methodology	YES
1764718	17225860	HL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1764718	17225860	HL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1764718	17225860	HL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1764718	17225860	IP	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1764718	17225860	KK	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1764718	17225860	KK	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1764718	17225860	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1764718	17225860	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1764718	17225860	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1764718	17225860	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5626879	29033962	AC	PLoS52	conceived and designed the study|drafted the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5626879	29033962	AC	PLoS52	conceived and designed the study|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5626879	29033962	All authors	PLoS52	have read and approved the manuscript	have read and approved the manuscript	-	-	NO
5626879	29033962	FK	PLoS52	conducted the rt-qpcr experiments	conducted the rt-qpcr experiments	Performed the experiments	Investigation	YES
5626879	29033962	GdF	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5626879	29033962	NR	PLoS52	conceived and designed the study|conducted in silico analysis|conducted the rt-qpcr experiments|analyzed the data|drafted the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5626879	29033962	NR	PLoS52	conceived and designed the study|conducted in silico analysis|conducted the rt-qpcr experiments|analyzed the data|drafted the manuscript	conducted in silico analysis	Performed the experiments	Formal analysis|Investigation	YES
5626879	29033962	NR	PLoS52	conceived and designed the study|conducted in silico analysis|conducted the rt-qpcr experiments|analyzed the data|drafted the manuscript	conducted the rt-qpcr experiments	Performed the experiments	Investigation	YES
5626879	29033962	NR	PLoS52	conceived and designed the study|conducted in silico analysis|conducted the rt-qpcr experiments|analyzed the data|drafted the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5626879	29033962	NR	PLoS52	conceived and designed the study|conducted in silico analysis|conducted the rt-qpcr experiments|analyzed the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5626879	29033962	RM	PLoS52	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3706344	23597059	AG	2	planned the study, evaluated data, oversaw the writing, and provided grant funding	planned the study, evaluated data, oversaw the writing, and provided grant funding	Conceived and designed the experiments|Wrote the paper	Conceptualization|Funding acquisition|Supervision	YES
3706344	23597059	BB	2	participated in planning and writing	participated in planning and writing	Conceived and designed the experiments|Wrote the paper	Methodology	YES
3706344	23597059	GAC	2	participated in planning and writing	participated in planning and writing	Conceived and designed the experiments|Wrote the paper	Methodology	YES
3706344	23597059	HLP	2	participated in planning of the human study, selected patients, evaluated the data and wrote the manuscript	participated in planning of the human study, selected patients, evaluated the data and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3706344	23597059	MK	2	participated in writing	participated in writing	Wrote the paper	-	YES
3706344	23597059	MS	2	planned the study, evaluated data, oversaw the writing, and provided grant funding	planned the study, evaluated data, oversaw the writing, and provided grant funding	Conceived and designed the experiments|Wrote the paper	Conceptualization|Funding acquisition|Supervision	YES
3706344	23597059	PN	2	participated in study planning, selected healthy controls, performed all lung spect analysis, evaluated data and wrote the manuscript	participated in study planning, selected healthy controls, performed all lung spect analysis, evaluated data and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4409317	25910039	JW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409317	25910039	JW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409317	25910039	JW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409317	25910039	JW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409317	25910039	JW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409317	25910039	LP	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4409317	25910039	LP	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409317	25910039	RQ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409317	25910039	RQ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409317	25910039	RQ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409317	25910039	RQ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409317	25910039	WZ	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4409317	25910039	WZ	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409317	25910039	YC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409317	25910039	YC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409317	25910039	YC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409317	25910039	YC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409317	25910039	YC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409317	25910039	YT	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4409317	25910039	YT	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1764720	17215958	FC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1764720	17215958	HY	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1764720	17215958	MG	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1764720	17215958	SC	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1764720	17215958	SC	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1764720	17215958	SZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Teaching technique	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1764720	17215958	SZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Teaching technique	Analyzed the data	Analyzed the data	Formal analysis	YES
1764720	17215958	SZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Teaching technique	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1764720	17215958	SZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Teaching technique	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1764720	17215958	SZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Teaching technique	Teaching technique	-	-	NO
1764720	17215958	YW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5626950	29033966	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5626950	29033966	BA	2	participated in the figure preparation	participated in the figure preparation	-	Visualization	YES
5626950	29033966	DH	2	participated in the sample preparation	participated in the sample preparation	Performed the experiments	Investigation	YES
5626950	29033966	KC	2	participated in the sample preparation	participated in the sample preparation	Performed the experiments	Investigation	YES
5626950	29033966	KH	2	performed the gene expression experiments	performed the gene expression experiments	Performed the experiments	Investigation	YES
5626950	29033966	SD	2	participated in planting the rice materials	participated in planting the rice materials	Performed the experiments	Investigation	YES
5626950	29033966	XH	2	participated in the gene cloning and complementary experiments	participated in the gene cloning and complementary experiments	Performed the experiments	Investigation	YES
5626950	29033966	XW	2	participated in planting the rice materials	participated in planting the rice materials	Performed the experiments	Investigation	YES
5626950	29033966	YL	2	participated in the vector construction	participated in the vector construction	Performed the experiments	Investigation	YES
5626950	29033966	YW	2	helped to prepare the figures and did partial writing	helped to prepare the figures and did partial writing	Wrote the paper	Visualization	YES
5626950	29033966	YsL	2	supervised the study and critically revised the manuscript	supervised the study and critically revised the manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
5626950	29033966	ZW	2	designed and participated in all the experimental procedures, performed the data analysis and also drafted the manuscript	designed and participated in all the experimental procedures, performed the data analysis and also drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
544600	15613238	AS	2	collected the data and performed most steps of bioinformatic and statistical analysis presented in the paper|designed the statistical tests applied in the study	collected the data and performed most steps of bioinformatic and statistical analysis presented in the paper	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
544600	15613238	AS	2	collected the data and performed most steps of bioinformatic and statistical analysis presented in the paper|designed the statistical tests applied in the study	designed the statistical tests applied in the study	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
544600	15613238	BL	2	designed and supervised the bioinformatic study, developed the initial framework for the analysis of the genomic sequences, made an independent observation about high incidence of clustering of super-conserved regions around genes encoding dna binding proteins, and annotated the ucr clusters with co-localizing genes|also co-wrote the manuscript	designed and supervised the bioinformatic study, developed the initial framework for the analysis of the genomic sequences, made an independent observation about high incidence of clustering of super-conserved regions around genes encoding dna binding proteins, and annotated the ucr clusters with co-localizing genes	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology|Supervision	YES
544600	15613238	BL	2	designed and supervised the bioinformatic study, developed the initial framework for the analysis of the genomic sequences, made an independent observation about high incidence of clustering of super-conserved regions around genes encoding dna binding proteins, and annotated the ucr clusters with co-localizing genes|also co-wrote the manuscript	also co-wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
544600	15613238	JE	2	initiated and co-supervised the study, which has the roots in his research in developmental neurobiology|also co-wrote the manuscript	initiated and co-supervised the study, which has the roots in his research in developmental neurobiology	Conceived and designed the experiments	Conceptualization|Supervision	YES
544600	15613238	JE	2	initiated and co-supervised the study, which has the roots in his research in developmental neurobiology|also co-wrote the manuscript	also co-wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
544600	15613238	PB	2	made initial analyses of putative regulatory elements on selected genes involved in neural tube development|discovered a number of super-conserved regions in the process, which helped create the rules for their genome-wide computational detection	made initial analyses of putative regulatory elements on selected genes involved in neural tube development	Analyzed the data	Formal analysis	YES
544600	15613238	PB	2	made initial analyses of putative regulatory elements on selected genes involved in neural tube development|discovered a number of super-conserved regions in the process, which helped create the rules for their genome-wide computational detection	discovered a number of super-conserved regions in the process, which helped create the rules for their genome-wide computational detection	Performed the experiments	Formal analysis|Investigation	YES
544600	15613238	PE	2	prepared genome sequence and annotation data for human, mouse and pufferfish|designed the statistical tests applied in the study	prepared genome sequence and annotation data for human, mouse and pufferfish	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
544600	15613238	PE	2	prepared genome sequence and annotation data for human, mouse and pufferfish|designed the statistical tests applied in the study	designed the statistical tests applied in the study	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
544600	15613238	SB	2	participated in the annotation of the gene set and in the creation of software for the visualization of results	participated in the annotation of the gene set and in the creation of software for the visualization of results	Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Formal analysis|Software|Visualization	YES
544600	15613238	WWW	2	participated in result interpretation, design of statistical tests, and writing later versions of the manuscript	participated in result interpretation, design of statistical tests, and writing later versions of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3707764	23829931	MEH	2	assisted with the interpretation of the biochemical assays within the context of the prkag2 model	assisted with the interpretation of the biochemical assays within the context of the prkag2 model	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
3707764	23829931	RSB	2	participated in the clinical implications and perspective on the fdg imaging data	participated in the clinical implications and perspective on the fdg imaging data	Analyzed the data	Visualization	YES
3707764	23829931	RdK	2	facilitated the application of kinetic modeling and quantification	facilitated the application of kinetic modeling and quantification	Performed the experiments	Methodology	YES
1764858	17245447	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1764858	17245447	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1764858	17245447	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1764858	17245447	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1764858	17245447	JB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1764858	17245447	JB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1764858	17245447	JB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1764858	17245447	JY	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1764858	17245447	JY	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1764858	17245447	JY	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409318	25909713	CFT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409318	25909713	CFT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409318	25909713	CFT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409318	25909713	CFT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409318	25909713	HCW	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409318	25909713	HWT	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409318	25909713	IJS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409318	25909713	IJS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409318	25909713	WCH	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409318	25909713	WH	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409318	25909713	YJL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5627015	29033953	BY	2	are the directors of the original research and paper writing	are the directors of the original research and paper writing	Wrote the paper	-	YES
5627015	29033953	CF	2	took charge of insect bioassay and herbicide resistant testing of transgenic lines	took charge of insect bioassay and herbicide resistant testing of transgenic lines	Performed the experiments	Investigation	YES
5627015	29033953	GX	2	took charge of field investigation of transgenic plants	took charge of field investigation of transgenic plants	Performed the experiments	Investigation	YES
5627015	29033953	JW	2	took charge of vector construction and molecular analysis of transformed plants	took charge of vector construction and molecular analysis of transformed plants	Performed the experiments	Investigation	YES
5627015	29033953	JZ	2	took charge of field investigation of transgenic plants	took charge of field investigation of transgenic plants	Performed the experiments	Investigation	YES
5627015	29033953	LS	2	took charge of data analysis and picture making	took charge of data analysis and picture making	Analyzed the data	Formal analysis|Visualization	YES
5627015	29033953	SZ	2	are the directors of the original research and paper writing	are the directors of the original research and paper writing	Wrote the paper	-	YES
5627015	29033953	TZ	2	took charge of original paper revising	took charge of original paper revising	-	-	NO
5627015	29033953	WW	2	took charge of genetic transformation and paper writing	took charge of genetic transformation and paper writing	Performed the experiments|Wrote the paper	Investigation	YES
5627015	29033953	XF	2	took charge of insect bioassay and herbicide resistant testing of transgenic lines	took charge of insect bioassay and herbicide resistant testing of transgenic lines	Performed the experiments	Investigation	YES
5627015	29033953	ZC	2	took charge of original paper revising	took charge of original paper revising	-	-	NO
5995313	29890048	AC	2	contributed to the interpretation and presentation of the findings	contributed to the interpretation and presentation of the findings	Analyzed the data	Formal analysis	YES
5995313	29890048	CI	2	designed and implemented the study|wrote the initial draft of the manuscript|contributed to the interpretation and presentation of the findings	designed and implemented the study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5995313	29890048	CI	2	designed and implemented the study|wrote the initial draft of the manuscript|contributed to the interpretation and presentation of the findings	wrote the initial draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
5995313	29890048	CI	2	designed and implemented the study|wrote the initial draft of the manuscript|contributed to the interpretation and presentation of the findings	contributed to the interpretation and presentation of the findings	Analyzed the data	Formal analysis	YES
5995313	29890048	DP	2	contributed to the interpretation and presentation of the findings	contributed to the interpretation and presentation of the findings	Analyzed the data	Formal analysis	YES
5995313	29890048	FD	2	contributed to the interpretation and presentation of the findings	contributed to the interpretation and presentation of the findings	Analyzed the data	Formal analysis	YES
5995313	29890048	KB	2	contributed to the interpretation and presentation of the findings	contributed to the interpretation and presentation of the findings	Analyzed the data	Formal analysis	YES
5995313	29890048	KP	2	contributed to the interpretation and presentation of the findings	contributed to the interpretation and presentation of the findings	Analyzed the data	Formal analysis	YES
5995313	29890048	MLN	2	contributed to the interpretation and presentation of the findings	contributed to the interpretation and presentation of the findings	Analyzed the data	Formal analysis	YES
5995313	29890048	NM	2	contributed to the interpretation and presentation of the findings	contributed to the interpretation and presentation of the findings	Analyzed the data	Formal analysis	YES
3708745	23829944	DJM	2	conducted the research for quantification using imaging markers	conducted the research for quantification using imaging markers	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
3708745	23829944	GK-M	2	designed the lab experiments including the imaging of mice|conducted the research for quantification using imaging markers	designed the lab experiments including the imaging of mice	Conceived and designed the experiments|Analyzed the data	Methodology|Visualization	YES
3708745	23829944	GK-M	2	designed the lab experiments including the imaging of mice|conducted the research for quantification using imaging markers	conducted the research for quantification using imaging markers	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
3708745	23829944	UB	2	conducted the research for quantification using imaging markers|developed the segmentation methods for quantitative and longitudinal analysis of small-animal images|wrote the software for segmentation evaluation test for inter- and intra-operator variation derivation|conducted all statistical tests, and two bio-statisticians independently checked those tests	conducted the research for quantification using imaging markers	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
3708745	23829944	UB	2	conducted the research for quantification using imaging markers|developed the segmentation methods for quantitative and longitudinal analysis of small-animal images|wrote the software for segmentation evaluation test for inter- and intra-operator variation derivation|conducted all statistical tests, and two bio-statisticians independently checked those tests	developed the segmentation methods for quantitative and longitudinal analysis of small-animal images	Performed the experiments|Analyzed the data	Methodology|Visualization	YES
3708745	23829944	UB	2	conducted the research for quantification using imaging markers|developed the segmentation methods for quantitative and longitudinal analysis of small-animal images|wrote the software for segmentation evaluation test for inter- and intra-operator variation derivation|conducted all statistical tests, and two bio-statisticians independently checked those tests	wrote the software for segmentation evaluation test for inter- and intra-operator variation derivation	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Software|Writing - Original Draft	YES
3708745	23829944	UB	2	conducted the research for quantification using imaging markers|developed the segmentation methods for quantitative and longitudinal analysis of small-animal images|wrote the software for segmentation evaluation test for inter- and intra-operator variation derivation|conducted all statistical tests, and two bio-statisticians independently checked those tests	conducted all statistical tests, and two bio-statisticians independently checked those tests	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5627020	29033958	CS	PLoS52	performed the experiments|analyzed the data|discussed the findings and interpreted the results|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5627020	29033958	CS	PLoS52	performed the experiments|analyzed the data|discussed the findings and interpreted the results|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5627020	29033958	CS	PLoS52	performed the experiments|analyzed the data|discussed the findings and interpreted the results|wrote the manuscript	discussed the findings and interpreted the results	Analyzed the data	Formal analysis	YES
5627020	29033958	CS	PLoS52	performed the experiments|analyzed the data|discussed the findings and interpreted the results|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5627020	29033958	CZ	PLoS52	conceived and designed the experiments|discussed the findings and interpreted the results	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5627020	29033958	CZ	PLoS52	conceived and designed the experiments|discussed the findings and interpreted the results	discussed the findings and interpreted the results	Analyzed the data	Formal analysis	YES
5627020	29033958	FB	PLoS52	performed the experiments|analyzed the data|discussed the findings and interpreted the results|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5627020	29033958	FB	PLoS52	performed the experiments|analyzed the data|discussed the findings and interpreted the results|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5627020	29033958	FB	PLoS52	performed the experiments|analyzed the data|discussed the findings and interpreted the results|wrote the manuscript	discussed the findings and interpreted the results	Analyzed the data	Formal analysis	YES
5627020	29033958	FB	PLoS52	performed the experiments|analyzed the data|discussed the findings and interpreted the results|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5627020	29033958	FV	PLoS52	conceived and designed the experiments|discussed the findings and interpreted the results	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5627020	29033958	FV	PLoS52	conceived and designed the experiments|discussed the findings and interpreted the results	discussed the findings and interpreted the results	Analyzed the data	Formal analysis	YES
5627020	29033958	GG	PLoS52	conceived and designed the experiments|discussed the findings and interpreted the results	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5627020	29033958	GG	PLoS52	conceived and designed the experiments|discussed the findings and interpreted the results	discussed the findings and interpreted the results	Analyzed the data	Formal analysis	YES
5627020	29033958	LS	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5627020	29033958	MD-R	PLoS52	conceived and designed the experiments|discussed the findings and interpreted the results|wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5627020	29033958	MD-R	PLoS52	conceived and designed the experiments|discussed the findings and interpreted the results|wrote the manuscript	discussed the findings and interpreted the results	Analyzed the data	Formal analysis	YES
5627020	29033958	MD-R	PLoS52	conceived and designed the experiments|discussed the findings and interpreted the results|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5627020	29033958	MS	PLoS52	conceived and designed the experiments|performed the experiments|discussed the findings and interpreted the results	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5627020	29033958	MS	PLoS52	conceived and designed the experiments|performed the experiments|discussed the findings and interpreted the results	performed the experiments	Performed the experiments	Investigation	YES
5627020	29033958	MS	PLoS52	conceived and designed the experiments|performed the experiments|discussed the findings and interpreted the results	discussed the findings and interpreted the results	Analyzed the data	Formal analysis	YES
5627020	29033958	SM	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5627020	29033958	VF	PLoS52	performed the experiments|analyzed the data|discussed the findings and interpreted the results	performed the experiments	Performed the experiments	Investigation	YES
5627020	29033958	VF	PLoS52	performed the experiments|analyzed the data|discussed the findings and interpreted the results	analyzed the data	Analyzed the data	Formal analysis	YES
5627020	29033958	VF	PLoS52	performed the experiments|analyzed the data|discussed the findings and interpreted the results	discussed the findings and interpreted the results	Analyzed the data	Formal analysis	YES
4409319	25909449	DS	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409319	25909449	DS	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409319	25909449	IAM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409319	25909449	IAM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409319	25909449	IAM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409319	25909449	IAM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409319	25909449	IAM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409319	25909449	JDR	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409319	25909449	JDR	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409319	25909449	MLJ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409319	25909449	NBP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409319	25909449	NBP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409319	25909449	NBP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409319	25909449	NBP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409319	25909449	SKD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409319	25909449	SKD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409319	25909449	SKD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409319	25909449	SKD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5446695	28549457	All authors	2	have analysed the data, contributed to the manuscript and approved the final version	have analysed the data, contributed to the manuscript and approved the final version	Analyzed the data	Formal analysis	YES
5446695	28549457	RNA	2	reads to the genome and prepared all figures and tables	reads to the genome and prepared all figures and tables	-	Visualization	YES
1764859	17245442	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1764859	17245442	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1764859	17245442	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1764859	17245442	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1764859	17245442	AR	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1764859	17245442	AR	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1764859	17245442	ML	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1764859	17245442	ML	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1764859	17245442	MP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1764859	17245442	MP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1764859	17245442	MP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1764859	17245442	PK	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1764859	17245442	PK	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1764859	17245442	PK	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1764859	17245442	PR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1764859	17245442	PR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1764859	17245442	PR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1764859	17245442	VG	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1764859	17245442	VG	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
6016621	29939488	DSK	2	contributed to the writing of the manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
6016621	29939488	JFD	2	conceptualized and designed the research study/grant|contributed to the writing of the manuscript	conceptualized and designed the research study/grant	Conceived and designed the experiments	Conceptualization|Methodology	YES
6016621	29939488	JFD	2	conceptualized and designed the research study/grant|contributed to the writing of the manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
6016621	29939488	JRB	2	conceptualized and designed the research study/grant	conceptualized and designed the research study/grant	Conceived and designed the experiments	Conceptualization|Methodology	YES
6016621	29939488	KHM	2	conceptualized and designed the research study/grant	conceptualized and designed the research study/grant	Conceived and designed the experiments	Conceptualization|Methodology	YES
6016621	29939488	KU	2	contributed to the writing of the manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
6016621	29939488	MM	2	conceptualized and designed the research study/grant|contributed to the writing of the manuscript	conceptualized and designed the research study/grant	Conceived and designed the experiments	Conceptualization|Methodology	YES
6016621	29939488	MM	2	conceptualized and designed the research study/grant|contributed to the writing of the manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
6016621	29939488	NBH	2	conceptualized and designed the research study/grant|contributed to the writing of the manuscript	conceptualized and designed the research study/grant	Conceived and designed the experiments	Conceptualization|Methodology	YES
6016621	29939488	NBH	2	conceptualized and designed the research study/grant|contributed to the writing of the manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
6016621	29939488	SKC	2	conceptualized and designed the research study/grant|executed the study and led the research analyses|contributed to the writing of the manuscript	conceptualized and designed the research study/grant	Conceived and designed the experiments	Conceptualization|Methodology	YES
6016621	29939488	SKC	2	conceptualized and designed the research study/grant|executed the study and led the research analyses|contributed to the writing of the manuscript	executed the study and led the research analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6016621	29939488	SKC	2	conceptualized and designed the research study/grant|executed the study and led the research analyses|contributed to the writing of the manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
6016621	29939488	TSK	2	conceptualized and designed the research study/grant	conceptualized and designed the research study/grant	Conceived and designed the experiments	Conceptualization|Methodology	YES
6016621	29939488	VAE	2	contributed to the writing of the manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
4319195	25674182	IH	2	participated in planning the study design, data interpretation and critically revised the manuscript	participated in planning the study design, data interpretation and critically revised the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
4319195	25674182	KF	2	participated in planning the study design, data interpretation and helped draft the manuscript	participated in planning the study design, data interpretation and helped draft the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4319195	25674182	MA	2	participated in planning the study design, gathered the data from the database, performed the statistical analyses, and drafted the manuscript	participated in planning the study design, gathered the data from the database, performed the statistical analyses, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Software|Writing - Original Draft	YES
4409320	25910232	CF	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409320	25910232	CF	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409320	25910232	CK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409320	25910232	CK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409320	25910232	CK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409320	25910232	CK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409320	25910232	GK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409320	25910232	GK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4409320	25910232	GK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409320	25910232	HK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409320	25910232	HK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4409320	25910232	HK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409320	25910232	LK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4409320	25910232	LK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409320	25910232	SP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409320	25910232	SP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409320	25910232	SP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409320	25910232	SP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5446715	28549425	DS	2	offered expertise to improve the manuscript and helped revise the draft	offered expertise to improve the manuscript and helped revise the draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5446715	28549425	EB	2	performed the simulation studies and real data analysis	performed the simulation studies and real data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5446715	28549425	JC	2	designed and implemented the method and drafted the manuscript under the|performed the simulation studies and real data analysis	designed and implemented the method and drafted the manuscript under the	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5446715	28549425	JC	2	designed and implemented the method and drafted the manuscript under the|performed the simulation studies and real data analysis	performed the simulation studies and real data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5446715	28549425	JH	2	performed the simulation studies and real data analysis	performed the simulation studies and real data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5446715	28549425	JX	2	performed the simulation studies and real data analysis	performed the simulation studies and real data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5446715	28549425	LL	2	supervised the designed and implemented the method and drafted the manuscript under the	supervised the designed and implemented the method and drafted the manuscript under the	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Supervision|Writing - Original Draft	YES
5446715	28549425	MM	2	contributed the real data set and aided in interpretation of the results	contributed the real data set and aided in interpretation of the results	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5446715	28549425	XL	2	supervised the designed and implemented the method and drafted the manuscript under the	supervised the designed and implemented the method and drafted the manuscript under the	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Supervision|Writing - Original Draft	YES
3717002	23497553	BBB	2	performed the pet measurements	performed the pet measurements	Performed the experiments	Investigation	YES
3717002	23497553	FH	2	performed part of the data analysis and wrote part of the manuscript	performed part of the data analysis and wrote part of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3717002	23497553	GS	2	contributed to the derivation of the theoretical background	contributed to the derivation of the theoretical background	-	Formal analysis	YES
3717002	23497553	JK	2	provided intellectual input and reviewed the manuscript	provided intellectual input and reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
3717002	23497553	JL	2	performed the pet measurements	performed the pet measurements	Performed the experiments	Investigation	YES
3717002	23497553	JS	2	provided intellectual input and reviewed the manuscript	provided intellectual input and reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
3717002	23497553	JVDH	2	derived the theoretical background, performed part of the data analysis, and is the main author of the manuscript	derived the theoretical background, performed part of the data analysis, and is the main author of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3717002	23497553	LO	2	contributed to the derivation of the theoretical background	contributed to the derivation of the theoretical background	-	Formal analysis	YES
5627026	29033959	JS	2	contributed to the drafting, editing and finalizing this editorial	contributed to the drafting, editing and finalizing this editorial	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5627026	29033959	LW	2	contributed to the drafting, editing and finalizing this editorial	contributed to the drafting, editing and finalizing this editorial	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
1764860	17225861	GD	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Did some of the bench-work, preliminary phylogenetic analyses, and assisted with the write-up of the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1764860	17225861	GD	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Did some of the bench-work, preliminary phylogenetic analyses, and assisted with the write-up of the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
1764860	17225861	GD	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Did some of the bench-work, preliminary phylogenetic analyses, and assisted with the write-up of the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1764860	17225861	GD	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Did some of the bench-work, preliminary phylogenetic analyses, and assisted with the write-up of the manuscript	Did some of the bench-work, preliminary phylogenetic analyses, and assisted with the write-up of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
1764860	17225861	PW	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Wrote the paper|Wrote the paper|Wrote the first draft, did most of the bench-work, the bioinformatic analysis, and data mining|Undertook most of the phylogenetic analyses and assisted with the write-up of the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1764860	17225861	PW	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Wrote the paper|Wrote the paper|Wrote the first draft, did most of the bench-work, the bioinformatic analysis, and data mining|Undertook most of the phylogenetic analyses and assisted with the write-up of the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1764860	17225861	PW	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Wrote the paper|Wrote the paper|Wrote the first draft, did most of the bench-work, the bioinformatic analysis, and data mining|Undertook most of the phylogenetic analyses and assisted with the write-up of the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
1764860	17225861	PW	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Wrote the paper|Wrote the paper|Wrote the first draft, did most of the bench-work, the bioinformatic analysis, and data mining|Undertook most of the phylogenetic analyses and assisted with the write-up of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
1764860	17225861	PW	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Wrote the paper|Wrote the paper|Wrote the first draft, did most of the bench-work, the bioinformatic analysis, and data mining|Undertook most of the phylogenetic analyses and assisted with the write-up of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
1764860	17225861	PW	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Wrote the paper|Wrote the paper|Wrote the first draft, did most of the bench-work, the bioinformatic analysis, and data mining|Undertook most of the phylogenetic analyses and assisted with the write-up of the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1764860	17225861	PW	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Wrote the paper|Wrote the paper|Wrote the first draft, did most of the bench-work, the bioinformatic analysis, and data mining|Undertook most of the phylogenetic analyses and assisted with the write-up of the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1764860	17225861	PW	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Wrote the paper|Wrote the paper|Wrote the first draft, did most of the bench-work, the bioinformatic analysis, and data mining|Undertook most of the phylogenetic analyses and assisted with the write-up of the manuscript	Wrote the first draft, did most of the bench-work, the bioinformatic analysis, and data mining	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
1764860	17225861	PW	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Wrote the paper|Wrote the paper|Wrote the first draft, did most of the bench-work, the bioinformatic analysis, and data mining|Undertook most of the phylogenetic analyses and assisted with the write-up of the manuscript	Undertook most of the phylogenetic analyses and assisted with the write-up of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
1764860	17225861	TR	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Provided funding, direction and assisted with the write-up of the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1764860	17225861	TR	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Provided funding, direction and assisted with the write-up of the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1764860	17225861	TR	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Provided funding, direction and assisted with the write-up of the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1764860	17225861	TR	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Provided funding, direction and assisted with the write-up of the manuscript	Provided funding, direction and assisted with the write-up of the manuscript	Wrote the paper	Funding acquisition|Writing - Original Draft	YES
3717018	23855995	All authors	2	contributed to the testing and refinement of the complete software package	contributed to the testing and refinement of the complete software package	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
3717018	23855995	ML	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3717018	23855995	RMvD	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3717018	23855995	SBC	2	programmed the client application|wrote the manuscript	programmed the client application	Contributed reagents/materials/analysis tools	Software	YES
3717018	23855995	SBC	2	programmed the client application|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6016637	29939483	All authors	2	were involved in the interpretation of the findings|commented extensively, revised the manuscript critically and approved the final version	were involved in the interpretation of the findings	Analyzed the data	Formal analysis	YES
6016637	29939483	All authors	2	were involved in the interpretation of the findings|commented extensively, revised the manuscript critically and approved the final version	commented extensively, revised the manuscript critically and approved the final version	Wrote the paper	Writing - Review & Editing	YES
4409321	25910191	AMA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409321	25910191	AMA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409321	25910191	AMA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409321	25910191	HYN	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409321	25910191	HYN	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409321	25910191	SMMAH	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409321	25910191	SMMAH	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5446728	28549456	All authors	PLoS52	reviewed and approved the final manuscript	reviewed and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5446728	28549456	BJ	PLoS52	participated in the design of the study|analyzed the data	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
5446728	28549456	BJ	PLoS52	participated in the design of the study|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5446728	28549456	CW	PLoS52	participated in the photo-thermal treatments and phenotypic data collection	participated in the photo-thermal treatments and phenotypic data collection	Performed the experiments	Investigation	YES
5446728	28549456	DW	PLoS52	designed the experiments and provided financial supports|wrote the manuscript	designed the experiments and provided financial supports	Conceived and designed the experiments	Funding acquisition|Methodology	YES
5446728	28549456	DW	PLoS52	designed the experiments and provided financial supports|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5446728	28549456	JL	PLoS52	performed phenotypic data collection|performed genotypic data collection|analyzed the data	performed phenotypic data collection	Performed the experiments	Investigation	YES
5446728	28549456	JL	PLoS52	performed phenotypic data collection|performed genotypic data collection|analyzed the data	performed genotypic data collection	Performed the experiments	Investigation	YES
5446728	28549456	JL	PLoS52	performed phenotypic data collection|performed genotypic data collection|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5446728	28549456	QS	PLoS52	participated in the design of the study|wrote the manuscript	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
5446728	28549456	QS	PLoS52	participated in the design of the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5446728	28549456	SS	PLoS52	participated in the design of the study|participated in the photo-thermal treatments and phenotypic data collection|revised the manuscript	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
5446728	28549456	SS	PLoS52	participated in the design of the study|participated in the photo-thermal treatments and phenotypic data collection|revised the manuscript	participated in the photo-thermal treatments and phenotypic data collection	Performed the experiments	Investigation	YES
5446728	28549456	SS	PLoS52	participated in the design of the study|participated in the photo-thermal treatments and phenotypic data collection|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5446728	28549456	TH	PLoS52	designed the experiments and provided financial supports|wrote the manuscript	designed the experiments and provided financial supports	Conceived and designed the experiments	Funding acquisition|Methodology	YES
5446728	28549456	TH	PLoS52	designed the experiments and provided financial supports|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5446728	28549456	TM	PLoS52	performed phenotypic data collection|performed genotypic data collection|analyzed the data|wrote the manuscript	performed phenotypic data collection	Performed the experiments	Investigation	YES
5446728	28549456	TM	PLoS52	performed phenotypic data collection|performed genotypic data collection|analyzed the data|wrote the manuscript	performed genotypic data collection	Performed the experiments	Investigation	YES
5446728	28549456	TM	PLoS52	performed phenotypic data collection|performed genotypic data collection|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5446728	28549456	TM	PLoS52	performed phenotypic data collection|performed genotypic data collection|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5446728	28549456	TW	PLoS52	analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5446728	28549456	TW	PLoS52	analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5446728	28549456	WH	PLoS52	participated in the design of the study|revised the manuscript	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
5446728	28549456	WH	PLoS52	participated in the design of the study|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5446728	28549456	WL	PLoS52	participated in the design of the study|revised the manuscript	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
5446728	28549456	WL	PLoS52	participated in the design of the study|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5446728	28549456	ZW	PLoS52	performed genotypic data collection|wrote the manuscript	performed genotypic data collection	Performed the experiments	Investigation	YES
5446728	28549456	ZW	PLoS52	performed genotypic data collection|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3717127	23849185	BM	2	built and tested the synthesizer	built and tested the synthesizer	Performed the experiments	Investigation	YES
3717127	23849185	GJS	2	designed the synthesizer	designed the synthesizer	Conceived and designed the experiments|Performed the experiments	Investigation	YES
3717127	23849185	HEH	2	contributed key design elements to the synthesizer and software	contributed key design elements to the synthesizer and software	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
3717127	23849185	JC	2	helped perform the radiosyntheses and collect specific activity data	helped perform the radiosyntheses and collect specific activity data	Performed the experiments	Investigation	YES
3717127	23849185	KMQ	2	designed the synthesizer|built and tested the synthesizer|designed the software architecture and user interface|implemented and tested the software|designed and performed experiments to characterize the synthesizer	designed the synthesizer	Conceived and designed the experiments|Performed the experiments	Investigation	YES
3717127	23849185	KMQ	2	designed the synthesizer|built and tested the synthesizer|designed the software architecture and user interface|implemented and tested the software|designed and performed experiments to characterize the synthesizer	built and tested the synthesizer	Performed the experiments	Investigation	YES
3717127	23849185	KMQ	2	designed the synthesizer|built and tested the synthesizer|designed the software architecture and user interface|implemented and tested the software|designed and performed experiments to characterize the synthesizer	designed the software architecture and user interface	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
3717127	23849185	KMQ	2	designed the synthesizer|built and tested the synthesizer|designed the software architecture and user interface|implemented and tested the software|designed and performed experiments to characterize the synthesizer	implemented and tested the software	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
3717127	23849185	KMQ	2	designed the synthesizer|built and tested the synthesizer|designed the software architecture and user interface|implemented and tested the software|designed and performed experiments to characterize the synthesizer	designed and performed experiments to characterize the synthesizer	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3717127	23849185	MDM	2	designed the synthesizer|designed the software architecture and user interface|conceived the project	designed the synthesizer	Conceived and designed the experiments|Performed the experiments	Investigation	YES
3717127	23849185	MDM	2	designed the synthesizer|designed the software architecture and user interface|conceived the project	designed the software architecture and user interface	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
3717127	23849185	MDM	2	designed the synthesizer|designed the software architecture and user interface|conceived the project	conceived the project	Conceived and designed the experiments	Conceptualization	YES
3717127	23849185	MEP	2	conceived the project	conceived the project	Conceived and designed the experiments	Conceptualization	YES
3717127	23849185	ML	2	designed the synthesizer|built and tested the synthesizer|designed the software architecture and user interface|designed and performed experiments to characterize the synthesizer|performed the radiosyntheses and analyses of synthesis data|wrote the manuscript	designed the synthesizer	Conceived and designed the experiments|Performed the experiments	Investigation	YES
3717127	23849185	ML	2	designed the synthesizer|built and tested the synthesizer|designed the software architecture and user interface|designed and performed experiments to characterize the synthesizer|performed the radiosyntheses and analyses of synthesis data|wrote the manuscript	built and tested the synthesizer	Performed the experiments	Investigation	YES
3717127	23849185	ML	2	designed the synthesizer|built and tested the synthesizer|designed the software architecture and user interface|designed and performed experiments to characterize the synthesizer|performed the radiosyntheses and analyses of synthesis data|wrote the manuscript	designed the software architecture and user interface	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
3717127	23849185	ML	2	designed the synthesizer|built and tested the synthesizer|designed the software architecture and user interface|designed and performed experiments to characterize the synthesizer|performed the radiosyntheses and analyses of synthesis data|wrote the manuscript	designed and performed experiments to characterize the synthesizer	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3717127	23849185	ML	2	designed the synthesizer|built and tested the synthesizer|designed the software architecture and user interface|designed and performed experiments to characterize the synthesizer|performed the radiosyntheses and analyses of synthesis data|wrote the manuscript	performed the radiosyntheses and analyses of synthesis data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3717127	23849185	ML	2	designed the synthesizer|built and tested the synthesizer|designed the software architecture and user interface|designed and performed experiments to characterize the synthesizer|performed the radiosyntheses and analyses of synthesis data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3717127	23849185	RMvD	2	designed the synthesizer|designed the software architecture and user interface|conceived the project|wrote the manuscript	designed the synthesizer	Conceived and designed the experiments|Performed the experiments	Investigation	YES
3717127	23849185	RMvD	2	designed the synthesizer|designed the software architecture and user interface|conceived the project|wrote the manuscript	designed the software architecture and user interface	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
3717127	23849185	RMvD	2	designed the synthesizer|designed the software architecture and user interface|conceived the project|wrote the manuscript	conceived the project	Conceived and designed the experiments	Conceptualization	YES
3717127	23849185	RMvD	2	designed the synthesizer|designed the software architecture and user interface|conceived the project|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3717127	23849185	SBC	2	designed the synthesizer|built and tested the synthesizer|designed the software architecture and user interface|implemented and tested the software|designed and performed experiments to characterize the synthesizer	designed the synthesizer	Conceived and designed the experiments|Performed the experiments	Investigation	YES
3717127	23849185	SBC	2	designed the synthesizer|built and tested the synthesizer|designed the software architecture and user interface|implemented and tested the software|designed and performed experiments to characterize the synthesizer	built and tested the synthesizer	Performed the experiments	Investigation	YES
3717127	23849185	SBC	2	designed the synthesizer|built and tested the synthesizer|designed the software architecture and user interface|implemented and tested the software|designed and performed experiments to characterize the synthesizer	designed the software architecture and user interface	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
3717127	23849185	SBC	2	designed the synthesizer|built and tested the synthesizer|designed the software architecture and user interface|implemented and tested the software|designed and performed experiments to characterize the synthesizer	implemented and tested the software	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
3717127	23849185	SBC	2	designed the synthesizer|built and tested the synthesizer|designed the software architecture and user interface|implemented and tested the software|designed and performed experiments to characterize the synthesizer	designed and performed experiments to characterize the synthesizer	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5627039	29033955	All authors	2	listed have made a substantial, direct and equal contribution to the work, and approved it for publication	listed have made a substantial, direct and equal contribution to the work, and approved it for publication	-	-	NO
3717131	23829959	CJ	2	participated in the study design, interpretation of the data and drafting of the manuscript	participated in the study design, interpretation of the data and drafting of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3717131	23829959	FB	2	participated in the study design and was responsible for the examinations	participated in the study design and was responsible for the examinations	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3717131	23829959	HJ	2	conceived the study, carried out many evaluations and participated in the interpretation of the data and drafting of the manuscript	conceived the study, carried out many evaluations and participated in the interpretation of the data and drafting of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
3717131	23829959	HL	2	carried out many evaluations and participated in the study design, interpretation of the data and drafting of the manuscript	carried out many evaluations and participated in the study design, interpretation of the data and drafting of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
1766343	17237885	AV	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1766343	17237885	AV	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1766343	17237885	LV	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1766343	17237885	LV	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1766343	17237885	NL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1766343	17237885	NL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1766343	17237885	NL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1766343	17237885	NL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1766343	17237885	PC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1766343	17237885	PC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1766343	17237885	VS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
6024120	29956491	AKG	2	conceptualized and drafted the commentary	conceptualized and drafted the commentary	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
6024120	29956491	DM	2	provided substantial feedback on the draft and subsequent revisions	provided substantial feedback on the draft and subsequent revisions	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6024120	29956491	JJA	2	provided substantial feedback on the draft and subsequent revisions	provided substantial feedback on the draft and subsequent revisions	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6024120	29956491	LTG	2	led the content analysis and also provided feedback on the draft and subsequent revisions	led the content analysis and also provided feedback on the draft and subsequent revisions	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6024120	29956491	PHS	2	provided substantial feedback on the draft and subsequent revisions	provided substantial feedback on the draft and subsequent revisions	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6024120	29956491	SM	2	provided substantial feedback on the draft and subsequent revisions	provided substantial feedback on the draft and subsequent revisions	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4409322	25910246	MB	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4409322	25910246	MB	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409322	25910246	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409322	25910246	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409322	25910246	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409322	25910246	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409322	25910246	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409322	25910246	UHT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409322	25910246	UHT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409322	25910246	UHT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409322	25910246	UHT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5446745	28549454	ESR	2	conceived of the study|designed and conducted the rearing experiments and dissections	conceived of the study	Conceived and designed the experiments	Conceptualization	YES
5446745	28549454	ESR	2	conceived of the study|designed and conducted the rearing experiments and dissections	designed and conducted the rearing experiments and dissections	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5446745	28549454	KS	2	performed all benchwork and genomics analyses	performed all benchwork and genomics analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5446745	28549454	MK	2	designed and conducted the rearing experiments and dissections	designed and conducted the rearing experiments and dissections	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3718724	23841937	KPW	2	participated in the animal studies and data analysis	participated in the animal studies and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3718724	23841937	KSI	2	participated in the tumor implant and design of experiments	participated in the tumor implant and design of experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3718724	23841937	MQW	2	performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
3718724	23841937	SCH	2	conceived the study, participated in its design, guided the data analysis, and helped draft the manuscript	conceived the study, participated in its design, guided the data analysis, and helped draft the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Supervision|Writing - Original Draft	YES
3718724	23841937	WM	2	participated in conceiving the study and in its design	participated in conceiving the study and in its design	Conceived and designed the experiments	Conceptualization|Methodology	YES
3718724	23841937	WS	2	participated in conceiving the study, performed the animal experiments and data analysis, and drafted the manuscript	participated in conceiving the study, performed the animal experiments and data analysis, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
6024144	29956496	All authors	2	have contributed to the preparation of the manuscript, read and approved the final acknowledgement draft	have contributed to the preparation of the manuscript, read and approved the final acknowledgement draft	Wrote the paper	Writing - Original Draft	YES
5627395	29033970	CF	7	Performed most of the experiments|Provided technical assistance	Performed most of the experiments	Performed the experiments	Investigation	YES
5627395	29033970	CF	7	Performed most of the experiments|Provided technical assistance	Provided technical assistance	Performed the experiments	Investigation	YES
5627395	29033970	DS-F	7	Wrote the article with contributions from all the authors	Wrote the article with contributions from all the authors	Wrote the paper	Writing - Original Draft	YES
5627395	29033970	GC	7	Conceived the original screening and research plans|Designed the experiments and analyzed the data|Wrote the article with contributions from all the authors	Conceived the original screening and research plans	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5627395	29033970	GC	7	Conceived the original screening and research plans|Designed the experiments and analyzed the data|Wrote the article with contributions from all the authors	Designed the experiments and analyzed the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5627395	29033970	GC	7	Conceived the original screening and research plans|Designed the experiments and analyzed the data|Wrote the article with contributions from all the authors	Wrote the article with contributions from all the authors	Wrote the paper	Writing - Original Draft	YES
5627395	29033970	IA	7	Conceived the original screening and research plans|Performed most of the experiments|Designed the experiments and analyzed the data	Conceived the original screening and research plans	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5627395	29033970	IA	7	Conceived the original screening and research plans|Performed most of the experiments|Designed the experiments and analyzed the data	Performed most of the experiments	Performed the experiments	Investigation	YES
5627395	29033970	IA	7	Conceived the original screening and research plans|Performed most of the experiments|Designed the experiments and analyzed the data	Designed the experiments and analyzed the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5627395	29033970	LN	7	Performed most of the experiments	Performed most of the experiments	Performed the experiments	Investigation	YES
5627395	29033970	SDD	7	Conceived the original screening and research plans|Designed the experiments and analyzed the data	Conceived the original screening and research plans	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5627395	29033970	SDD	7	Conceived the original screening and research plans|Designed the experiments and analyzed the data	Designed the experiments and analyzed the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
1766371	17218990	AN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1766371	17218990	AN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1766371	17218990	AN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1766371	17218990	BB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1766371	17218990	BB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1766371	17218990	BB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1766371	17218990	BB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1766371	17218990	CE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1766371	17218990	CE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1766371	17218990	CE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1766371	17218990	CE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1766371	17218990	CV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1766371	17218990	CV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1766371	17218990	CV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1766371	17218990	EC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1766371	17218990	EC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1766371	17218990	EC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1766371	17218990	EC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1766371	17218990	EK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1766371	17218990	EK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1766371	17218990	EK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1766371	17218990	EK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1766371	17218990	EK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1766371	17218990	EM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1766371	17218990	EM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1766371	17218990	EM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1766371	17218990	EM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1766371	17218990	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1766371	17218990	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1766371	17218990	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1766371	17218990	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1766371	17218990	LE	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1766371	17218990	LE	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1766371	17218990	LE	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1766371	17218990	LS	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1766371	17218990	LS	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1766371	17218990	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1766371	17218990	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1766371	17218990	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1766371	17218990	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1766371	17218990	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1766371	17218990	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1766371	17218990	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1766371	17218990	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1766371	17218990	MP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1766371	17218990	MP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1766371	17218990	MP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1766371	17218990	MP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1766371	17218990	MP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1766371	17218990	MR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1766371	17218990	MR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1766371	17218990	MR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1766371	17218990	MR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1766371	17218990	SE	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1766371	17218990	SE	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1766371	17218990	SE	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1766371	17218990	SE	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1766371	17218990	SF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1766371	17218990	SF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1766371	17218990	SF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1766371	17218990	SF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1766371	17218990	SF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1766371	17218990	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1766371	17218990	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1766371	17218990	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1766371	17218990	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1766371	17218990	YD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1766371	17218990	YD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1766371	17218990	YD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1766371	17218990	YD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409323	25909382	AG	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409323	25909382	AG	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409323	25909382	AW	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409323	25909382	AW	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409323	25909382	SMA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409323	25909382	SMA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409323	25909382	SMA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409323	25909382	SMA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409323	25909382	YB	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409323	25909382	YB	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3726297	23883566	AEHT	2	were involved in study design, implementation, analysis, and manuscript preparation	were involved in study design, implementation, analysis, and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
3726297	23883566	AG	2	were involved in radioembolization, angiographic analysis, and manuscript preparation	were involved in radioembolization, angiographic analysis, and manuscript preparation	Wrote the paper	Writing - Original Draft	YES
3726297	23883566	ASWG	2	were involved in study design, implementation, analysis, and manuscript preparation	were involved in study design, implementation, analysis, and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
3726297	23883566	AT	2	was involved in histopathological analysis and manuscript preparation	was involved in histopathological analysis and manuscript preparation	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3726297	23883566	BST	2	were involved in radioembolization, angiographic analysis, and manuscript preparation	were involved in radioembolization, angiographic analysis, and manuscript preparation	Wrote the paper	Writing - Original Draft	YES
3726297	23883566	DCEN	2	were involved in study design, implementation, analysis, and manuscript preparation	were involved in study design, implementation, analysis, and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
3726297	23883566	DWT	2	were involved in study design, scan optimization, and manuscript preparation	were involved in study design, scan optimization, and manuscript preparation	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3726297	23883566	FGI	2	were involved in radioembolization, angiographic analysis, and manuscript preparation	were involved in radioembolization, angiographic analysis, and manuscript preparation	Wrote the paper	Writing - Original Draft	YES
3726297	23883566	GKYL	2	were involved in study design, implementation, analysis, and manuscript preparation	were involved in study design, implementation, analysis, and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
3726297	23883566	JDS	2	were involved in study design, scan optimization, and manuscript preparation	were involved in study design, scan optimization, and manuscript preparation	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3726297	23883566	JY	2	were involved in study design, scan optimization, and manuscript preparation	were involved in study design, scan optimization, and manuscript preparation	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3726297	23883566	KHT	2	were involved in radioembolization, angiographic analysis, and manuscript preparation	were involved in radioembolization, angiographic analysis, and manuscript preparation	Wrote the paper	Writing - Original Draft	YES
3726297	23883566	MCB	2	were involved in radioembolization, angiographic analysis, and manuscript preparation	were involved in radioembolization, angiographic analysis, and manuscript preparation	Wrote the paper	Writing - Original Draft	YES
3726297	23883566	PKHC	2	was involved in clinical care and manuscript preparation	was involved in clinical care and manuscript preparation	Wrote the paper	Writing - Original Draft	YES
3726297	23883566	RHGL	2	were involved in radioembolization, angiographic analysis, and manuscript preparation	were involved in radioembolization, angiographic analysis, and manuscript preparation	Wrote the paper	Writing - Original Draft	YES
3726297	23883566	SS	2	were involved in study design, implementation, analysis, and manuscript preparation	were involved in study design, implementation, analysis, and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
3726297	23883566	TKBT	2	were involved in radioembolization, angiographic analysis, and manuscript preparation	were involved in radioembolization, angiographic analysis, and manuscript preparation	Wrote the paper	Writing - Original Draft	YES
3726297	23883566	TNY	2	were involved in radioembolization, angiographic analysis, and manuscript preparation	were involved in radioembolization, angiographic analysis, and manuscript preparation	Wrote the paper	Writing - Original Draft	YES
3726297	23883566	YHK	2	were involved in study design, implementation, analysis, and manuscript preparation	were involved in study design, implementation, analysis, and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
3726297	23883566	YST	2	were involved in study design, implementation, analysis, and manuscript preparation	were involved in study design, implementation, analysis, and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
6024257	29956882	AA	2	conducted the analysis, led interpretations and contributed to manuscript writing	conducted the analysis, led interpretations and contributed to manuscript writing	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6024257	29956882	ADH	2	contributed data and reviewed the manuscript	contributed data and reviewed the manuscript	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Review & Editing	YES
6024257	29956882	AGA	2	contributed data and reviewed the manuscript	contributed data and reviewed the manuscript	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Review & Editing	YES
6024257	29956882	CM	2	contributed data and reviewed the manuscript	contributed data and reviewed the manuscript	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Review & Editing	YES
6024257	29956882	KW-K	2	contributed data and reviewed the manuscript	contributed data and reviewed the manuscript	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Review & Editing	YES
6024257	29956882	LMP	2	contributed data and reviewed the manuscript	contributed data and reviewed the manuscript	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Review & Editing	YES
6024257	29956882	MC	2	contributed data and reviewed the manuscript	contributed data and reviewed the manuscript	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Review & Editing	YES
6024257	29956882	MGL	2	who also contributed to the analysis and interpretation of results	who also contributed to the analysis and interpretation of results	Analyzed the data	Formal analysis	YES
6024257	29956882	MJG	2	contributed data and reviewed the manuscript	contributed data and reviewed the manuscript	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Review & Editing	YES
6024257	29956882	ML	2	contributed data and reviewed the manuscript	contributed data and reviewed the manuscript	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Review & Editing	YES
6024257	29956882	MLG	2	conceived the project and contributed to manuscript writing	conceived the project and contributed to manuscript writing	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
6024257	29956882	NdR	2	contributed data and reviewed the manuscript	contributed data and reviewed the manuscript	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Review & Editing	YES
6024257	29956882	PB	2	contributed data and reviewed the manuscript	contributed data and reviewed the manuscript	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Review & Editing	YES
6024257	29956882	RB	2	contributed data and reviewed the manuscript	contributed data and reviewed the manuscript	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Review & Editing	YES
4539432	26345532	Jung-Woo Seo	2	equally contributed to this study as first authors	equally contributed to this study as first authors	-	-	NO
4539432	26345532	Yang Gyun Kim	2	equally contributed to this study as first authors	equally contributed to this study as first authors	-	-	NO
4493649	26161155	Ian D. Ferguson	1	Acquisition, analysis, and interpretation of the data|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content	Acquisition, analysis, and interpretation of the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4493649	26161155	Ian D. Ferguson	1	Acquisition, analysis, and interpretation of the data|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content	Drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
4493649	26161155	Ian D. Ferguson	1	Acquisition, analysis, and interpretation of the data|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content	Critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4493649	26161155	Kathryn S. Torok	1	Acquisition, analysis, and interpretation of the data|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content	Acquisition, analysis, and interpretation of the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4493649	26161155	Kathryn S. Torok	1	Acquisition, analysis, and interpretation of the data|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content	Drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
4493649	26161155	Kathryn S. Torok	1	Acquisition, analysis, and interpretation of the data|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content	Critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4493649	26161155	MD	1	Acquisition, analysis, and interpretation of the data|Acquisition, analysis, and interpretation of the data|Acquisition, analysis, and interpretation of the data	Acquisition, analysis, and interpretation of the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4493649	26161155	MD	1	Acquisition, analysis, and interpretation of the data|Acquisition, analysis, and interpretation of the data|Acquisition, analysis, and interpretation of the data	Acquisition, analysis, and interpretation of the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4493649	26161155	MD	1	Acquisition, analysis, and interpretation of the data|Acquisition, analysis, and interpretation of the data|Acquisition, analysis, and interpretation of the data	Acquisition, analysis, and interpretation of the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4493649	26161155	Peter Weiser	1	Acquisition, analysis, and interpretation of the data|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content	Acquisition, analysis, and interpretation of the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4493649	26161155	Peter Weiser	1	Acquisition, analysis, and interpretation of the data|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content	Drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
4493649	26161155	Peter Weiser	1	Acquisition, analysis, and interpretation of the data|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content	Critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
3733807	23902737	ET	2	designed the study and drafted the manuscript	designed the study and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3733807	23902737	LE	2	designed the study and drafted the manuscript	designed the study and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3733807	23902737	MO	2	performed the statistical analysis and helped draft the manuscript	performed the statistical analysis and helped draft the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
1766372	17218991	AC	PLoS5	Contributed reagents/materials/analysis tools|Edited the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1766372	17218991	AC	PLoS5	Contributed reagents/materials/analysis tools|Edited the paper	Edited the paper	Wrote the paper	Writing - Review & Editing	YES
1766372	17218991	CS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1766372	17218991	JS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1766372	17218991	JS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1766372	17218991	JS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1766372	17218991	MM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1766372	17218991	MM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1766372	17218991	MM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1766372	17218991	PE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1766372	17218991	PE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1766372	17218991	PE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1766372	17218991	PE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1766372	17218991	VM	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
544879	15588320	AF	2	supported the gene annotations and the def structure and function discussions	supported the gene annotations and the def structure and function discussions	Analyzed the data	Data curation|Formal analysis	YES
544879	15588320	AS	2	accounted for the assembly revision and the lcr analyses	accounted for the assembly revision and the lcr analyses	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
544879	15588320	IFLs	2	fish experiments	fish experiments	-	-	NO
544879	15588320	KH	2	were in charge for the individual haplotype and copy number determinations	were in charge for the individual haplotype and copy number determinations	Performed the experiments	Investigation	YES
544879	15588320	KR	2	contributed to the sequencing process of clones in the region|were in charge for the individual haplotype and copy number determinations	contributed to the sequencing process of clones in the region	Performed the experiments	Investigation	YES
544879	15588320	KR	2	contributed to the sequencing process of clones in the region|were in charge for the individual haplotype and copy number determinations	were in charge for the individual haplotype and copy number determinations	Performed the experiments	Investigation	YES
544879	15588320	KS	2	accounted for the assembly revision and the lcr analyses	accounted for the assembly revision and the lcr analyses	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
544879	15588320	LCR	2	chimpanzee sequence analyses and drafted the manuscript	chimpanzee sequence analyses and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
544879	15588320	MP	2	conceived, designed and coordinated the project	conceived, designed and coordinated the project	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
544879	15588320	MS	2	accounted for the assembly revision and the lcr analyses	accounted for the assembly revision and the lcr analyses	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
544879	15588320	NS	2	accounted for the assembly revision and the lcr analyses	accounted for the assembly revision and the lcr analyses	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
544879	15588320	PG	2	performed mapping and repeat analyses in the 8p23	performed mapping and repeat analyses in the 8p23	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
544879	15588320	RS	2	supported the gene annotations and the def structure and function discussions	supported the gene annotations and the def structure and function discussions	Analyzed the data	Data curation|Formal analysis	YES
544879	15588320	SA	2	accounted for the assembly revision and the lcr analyses	accounted for the assembly revision and the lcr analyses	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
544879	15588320	SNP	2	chimpanzee sequence analyses and drafted the manuscript	chimpanzee sequence analyses and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5627460	29033963	BKH	2	added his previous bacterial data and expertise to upgrade the whole text and figures	added his previous bacterial data and expertise to upgrade the whole text and figures	-	Visualization	YES
6031071	29972632	AE	2	contributed to data collection, and reviewed and edited the manuscript	contributed to data collection, and reviewed and edited the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
6031071	29972632	CC	2	contributed to data collection, and reviewed and edited the manuscript	contributed to data collection, and reviewed and edited the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
6031071	29972632	EA	2	contributed to the writing of the protocol, the questionnaire, and the manuscript, and analysed the data	contributed to the writing of the protocol, the questionnaire, and the manuscript, and analysed the data	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Original Draft	YES
6031071	29972632	KAR	2	contributed to data collection, and reviewed and edited the manuscript	contributed to data collection, and reviewed and edited the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
6031071	29972632	KK	2	contributed to data collection, and reviewed and edited the manuscript	contributed to data collection, and reviewed and edited the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
6031071	29972632	MAD	2	contributed to data collection, and reviewed and edited the manuscript	contributed to data collection, and reviewed and edited the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
6031071	29972632	PL	2	contributed to data collection, and reviewed and edited the manuscript	contributed to data collection, and reviewed and edited the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
6031071	29972632	RCV	2	contributed to the writing of the protocol and the questionnaire, data collection and reviewed and edited the manuscript	contributed to the writing of the protocol and the questionnaire, data collection and reviewed and edited the manuscript	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
6031071	29972632	SA	2	contributed to the writing of the protocol and the questionnaire, data collection and reviewed and edited the manuscript	contributed to the writing of the protocol and the questionnaire, data collection and reviewed and edited the manuscript	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
6031071	29972632	SMF	2	contributed to data collection, and reviewed and edited the manuscript	contributed to data collection, and reviewed and edited the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
6031071	29972632	SND	2	contributed to data collection and preparation, and review of the manuscript	contributed to data collection and preparation, and review of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
6031071	29972632	VL	2	contributed to the writing of the questionnaire and data collection and reviewed and edited the manuscript	contributed to the writing of the questionnaire and data collection and reviewed and edited the manuscript	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
3733998	23731789	AH	2	analyzed and interpreted the pet imaging data	analyzed and interpreted the pet imaging data	Analyzed the data	Formal analysis|Visualization	YES
3733998	23731789	CV	2	acquired the neuropsychological data|carried out the biological sample analyses	acquired the neuropsychological data	Performed the experiments	Investigation	YES
3733998	23731789	CV	2	acquired the neuropsychological data|carried out the biological sample analyses	carried out the biological sample analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3733998	23731789	EJB	2	conceived of the study, participated in its design and coordination, and helped draft the manuscript	conceived of the study, participated in its design and coordination, and helped draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
3733998	23731789	FB	2	analyzed and interpreted the mri imaging data	analyzed and interpreted the mri imaging data	Analyzed the data	Formal analysis|Visualization	YES
3733998	23731789	FC	2	contributed to the conception and design of the study	contributed to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3733998	23731789	FN	2	analyzed the imaging data	analyzed the imaging data	Analyzed the data	Formal analysis|Visualization	YES
3733998	23731789	HM	2	acquired the neuropsychological data	acquired the neuropsychological data	Performed the experiments	Investigation	YES
3733998	23731789	JP	2	conceived of the study, participated in its design and coordination, and helped draft the manuscript	conceived of the study, participated in its design and coordination, and helped draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
3733998	23731789	LSA	2	participated in acquiring and interpreting the data, performed the statistical analysis, and drafted the manuscript	participated in acquiring and interpreting the data, performed the statistical analysis, and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3733998	23731789	MP	2	acquired the clinical data	acquired the clinical data	Performed the experiments	Investigation	YES
3733998	23731789	MT	2	acquired the pet imaging data	acquired the pet imaging data	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
3733998	23731789	PaP	2	analyzed the imaging data and revised the manuscript	analyzed the imaging data and revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Visualization|Writing - Review & Editing	YES
3733998	23731789	PiP	2	analyzed and interpreted the pet imaging data	analyzed and interpreted the pet imaging data	Analyzed the data	Formal analysis|Visualization	YES
3733998	23731789	RG	2	analyzed and interpreted the mri imaging data	analyzed and interpreted the mri imaging data	Analyzed the data	Formal analysis|Visualization	YES
3733998	23731789	SD	2	acquired the clinical data	acquired the clinical data	Performed the experiments	Investigation	YES
4409324	25909711	AH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409324	25909711	AH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409324	25909711	AH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409324	25909711	AH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409324	25909711	AHP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409324	25909711	AHP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409324	25909711	AHP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409324	25909711	AY	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409324	25909711	AY	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409324	25909711	CMKV	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409324	25909711	EK	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4409324	25909711	EK	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409324	25909711	FA-O	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409324	25909711	HES	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409324	25909711	KGP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409324	25909711	KLM	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409324	25909711	KLM	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409324	25909711	KN	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409324	25909711	KRKR	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409324	25909711	LJW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409324	25909711	LJW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409324	25909711	LJW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409324	25909711	MC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409324	25909711	MM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409324	25909711	MS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409324	25909711	R. Serraj	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409324	25909711	R. Shestha	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409324	25909711	RCB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409324	25909711	RCB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409324	25909711	RCB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409324	25909711	RM	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409324	25909711	RRS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4409324	25909711	RRS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409324	25909711	SMP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409324	25909711	VB	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409324	25909711	VDV	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409324	25909711	VG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409324	25909711	VS	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409324	25909711	VV	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409324	25909711	ZA-S	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
544882	15627404	Both authors	2	participated on sequence alignment, phylogenetic analysis and writing of the manuscript	participated on sequence alignment, phylogenetic analysis and writing of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
544882	15627404	MSB	2	carried out all psi-blast searches, generated local sequence databases, and drafted the initial manuscript	carried out all psi-blast searches, generated local sequence databases, and drafted the initial manuscript	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Software|Writing - Original Draft	YES
1766463	17245448	CT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1766463	17245448	CT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1766463	17245448	CT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1766463	17245448	DS	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1766463	17245448	DS	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1766463	17245448	EK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1766463	17245448	HJ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1766463	17245448	KK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1766463	17245448	SK	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1766463	17245448	TY	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1766463	17245448	WK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1766463	17245448	WK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1766463	17245448	WK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1766463	17245448	WK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1766463	17245448	YB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
3733999	23885971	AEHT	2	were involved in the study design, implementation, analysis, and manuscript preparation	were involved in the study design, implementation, analysis, and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
3733999	23885971	ASWG	2	were involved in the study design, implementation, analysis, and manuscript preparation	were involved in the study design, implementation, analysis, and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
3733999	23885971	BST	2	were involved in the radioembolization, angiographic analysis, and manuscript preparation	were involved in the radioembolization, angiographic analysis, and manuscript preparation	Wrote the paper	Writing - Original Draft	YES
3733999	23885971	CB	2	were involved in the data analysis and manuscript preparation	were involved in the data analysis and manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3733999	23885971	DCEN	2	were involved in the study design, implementation, analysis, and manuscript preparation	were involved in the study design, implementation, analysis, and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
3733999	23885971	DWT	2	were involved in the study design, scan optimization, and manuscript preparation	were involved in the study design, scan optimization, and manuscript preparation	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3733999	23885971	FGI	2	were involved in the radioembolization, angiographic analysis, and manuscript preparation	were involved in the radioembolization, angiographic analysis, and manuscript preparation	Wrote the paper	Writing - Original Draft	YES
3733999	23885971	GKYL	2	were involved in the study design, implementation, analysis, and manuscript preparation	were involved in the study design, implementation, analysis, and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
3733999	23885971	JAB	2	were involved in the data analysis and manuscript preparation	were involved in the data analysis and manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3733999	23885971	JDS	2	were involved in the study design, scan optimization, and manuscript preparation	were involved in the study design, scan optimization, and manuscript preparation	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3733999	23885971	JY	2	were involved in the study design, scan optimization, and manuscript preparation	were involved in the study design, scan optimization, and manuscript preparation	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3733999	23885971	KHT	2	were involved in the radioembolization, angiographic analysis, and manuscript preparation	were involved in the radioembolization, angiographic analysis, and manuscript preparation	Wrote the paper	Writing - Original Draft	YES
3733999	23885971	MCB	2	were involved in the radioembolization, angiographic analysis, and manuscript preparation	were involved in the radioembolization, angiographic analysis, and manuscript preparation	Wrote the paper	Writing - Original Draft	YES
3733999	23885971	PKHC	2	was involved in the clinical care and manuscript preparation	was involved in the clinical care and manuscript preparation	Wrote the paper	Writing - Original Draft	YES
3733999	23885971	RHGL	2	were involved in the radioembolization, angiographic analysis, and manuscript preparation	were involved in the radioembolization, angiographic analysis, and manuscript preparation	Wrote the paper	Writing - Original Draft	YES
3733999	23885971	RJF	2	were involved in the data analysis and manuscript preparation	were involved in the data analysis and manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3733999	23885971	SS	2	were involved in the study design, implementation, analysis, and manuscript preparation	were involved in the study design, implementation, analysis, and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
3733999	23885971	TSTC	2	were involved in the data analysis and manuscript preparation	were involved in the data analysis and manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3733999	23885971	YHK	2	were involved in the study design, implementation, analysis, and manuscript preparation	were involved in the study design, implementation, analysis, and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
3733999	23885971	YST	2	were involved in the study design, implementation, analysis, and manuscript preparation	were involved in the study design, implementation, analysis, and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5627545	29033960	AA	2	contributed to review and final version of the manuscript	contributed to review and final version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5627545	29033960	HP	2	collected crop data	collected crop data	Performed the experiments	Investigation	YES
5627545	29033960	ML	2	contributed to review the manuscript	contributed to review the manuscript	Wrote the paper	Writing - Review & Editing	YES
5627545	29033960	MU	2	design the modeling study, perform the model analysis, synthesized results and constructed tables, figures for the paper and created the first draft	design the modeling study, perform the model analysis, synthesized results and constructed tables, figures for the paper and created the first draft	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Visualization|Writing - Original Draft	YES
5627545	29033960	YQ	2	collected weather and manage the field	collected weather and manage the field	Performed the experiments	Investigation	YES
5627545	29033960	YS	2	design the study and review the results	design the study and review the results	Conceived and designed the experiments	Methodology	YES
5627545	29033960	YZ	2	collected crop data	collected crop data	Performed the experiments	Investigation	YES
6031072	29972628	All authors	2	contributed to design the study|contributed to read and revised the final manuscript	contributed to design the study	Conceived and designed the experiments	Methodology	YES
6031072	29972628	All authors	2	contributed to design the study|contributed to read and revised the final manuscript	contributed to read and revised the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6031072	29972628	CFH	2	helped to collect the data	helped to collect the data	Performed the experiments	Investigation	YES
6031072	29972628	H-YK	2	helped to collect the data|contributed to analyse the data|wrote the initial draft of the paper	helped to collect the data	Performed the experiments	Investigation	YES
6031072	29972628	H-YK	2	helped to collect the data|contributed to analyse the data|wrote the initial draft of the paper	contributed to analyse the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6031072	29972628	H-YK	2	helped to collect the data|contributed to analyse the data|wrote the initial draft of the paper	wrote the initial draft of the paper	Wrote the paper	Writing - Original Draft	YES
6031072	29972628	JFPB	2	contributed to analyse the data	contributed to analyse the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6031072	29972628	NM	2	helped to collect the data	helped to collect the data	Performed the experiments	Investigation	YES
1766470	17245450	AP	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1766470	17245450	AP	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1766470	17245450	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1766470	17245450	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1766470	17245450	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1766470	17245450	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1766470	17245450	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1766470	17245450	JD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1766470	17245450	JD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1766470	17245450	JD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409332	25909595	DB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409332	25909595	DB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409332	25909595	DB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409332	25909595	HLQ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409332	25909595	HLQ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409332	25909595	HLQ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409332	25909595	HLQ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409332	25909595	HLQ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409332	25909595	JDS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409332	25909595	JDS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409332	25909595	JDS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409332	25909595	MM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409332	25909595	MM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409332	25909595	MM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409332	25909595	PACL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409332	25909595	PACL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409332	25909595	PACL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409332	25909595	PACL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409332	25909595	PACL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409332	25909595	PLJ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409332	25909595	PLJ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409332	25909595	PLJ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409332	25909595	PP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409332	25909595	PP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409332	25909595	PP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409332	25909595	RN	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409332	25909595	RN	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409332	25909595	RN	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409332	25909595	SY	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409332	25909595	SY	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409332	25909595	SY	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409332	25909595	TM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409332	25909595	TM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409332	25909595	TM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
544889	15598354	AC	2	designed the study|supervised the analysis and participated in the manuscript preparation	designed the study	Conceived and designed the experiments	Methodology	YES
544889	15598354	AC	2	designed the study|supervised the analysis and participated in the manuscript preparation	supervised the analysis and participated in the manuscript preparation	Wrote the paper	Supervision|Writing - Original Draft	YES
544889	15598354	DG	2	designed the study|supervised the analysis and participated in the manuscript preparation	designed the study	Conceived and designed the experiments	Methodology	YES
544889	15598354	DG	2	designed the study|supervised the analysis and participated in the manuscript preparation	supervised the analysis and participated in the manuscript preparation	Wrote the paper	Supervision|Writing - Original Draft	YES
544889	15598354	RS	2	designed the study|carried out the statistical analysis and prepared the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
544889	15598354	RS	2	designed the study|carried out the statistical analysis and prepared the manuscript	carried out the statistical analysis and prepared the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3734217	23879987	BF	2	prepared all figures and tables	prepared all figures and tables	-	Visualization	YES
3734217	23879987	CBJ	2	co-initiated the project and designed the research|designed and performed the lab experiments for ferret data	co-initiated the project and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
3734217	23879987	CBJ	2	co-initiated the project and designed the research|designed and performed the lab experiments for ferret data	designed and performed the lab experiments for ferret data	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3734217	23879987	DJM	2	co-initiated the project and designed the research|designed a segmentation evaluation test for inter- and intra-operator variation derivation	co-initiated the project and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
3734217	23879987	DJM	2	co-initiated the project and designed the research|designed a segmentation evaluation test for inter- and intra-operator variation derivation	designed a segmentation evaluation test for inter- and intra-operator variation derivation	Conceived and designed the experiments|Performed the experiments	Investigation	YES
3734217	23879987	KMJ	2	developed the image processing algorithms for quantitative and longitudinal analysis of small animal images|prepared all figures and tables|conducted all statistical tests	developed the image processing algorithms for quantitative and longitudinal analysis of small animal images	Analyzed the data|Contributed reagents/materials/analysis tools	Software|Visualization	YES
3734217	23879987	KMJ	2	developed the image processing algorithms for quantitative and longitudinal analysis of small animal images|prepared all figures and tables|conducted all statistical tests	prepared all figures and tables	-	Visualization	YES
3734217	23879987	KMJ	2	developed the image processing algorithms for quantitative and longitudinal analysis of small animal images|prepared all figures and tables|conducted all statistical tests	conducted all statistical tests	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3734217	23879987	SJ	2	co-initiated the project and designed the research	co-initiated the project and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
3734217	23879987	UB	2	co-initiated the project and designed the research|developed the image processing algorithms for quantitative and longitudinal analysis of small animal images|wrote the software for all algorithms|prepared all figures and tables|designed a segmentation evaluation test for inter- and intra-operator variation derivation|conducted all statistical tests	co-initiated the project and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
3734217	23879987	UB	2	co-initiated the project and designed the research|developed the image processing algorithms for quantitative and longitudinal analysis of small animal images|wrote the software for all algorithms|prepared all figures and tables|designed a segmentation evaluation test for inter- and intra-operator variation derivation|conducted all statistical tests	developed the image processing algorithms for quantitative and longitudinal analysis of small animal images	Analyzed the data|Contributed reagents/materials/analysis tools	Software|Visualization	YES
3734217	23879987	UB	2	co-initiated the project and designed the research|developed the image processing algorithms for quantitative and longitudinal analysis of small animal images|wrote the software for all algorithms|prepared all figures and tables|designed a segmentation evaluation test for inter- and intra-operator variation derivation|conducted all statistical tests	wrote the software for all algorithms	Contributed reagents/materials/analysis tools|Wrote the paper	Software|Writing - Original Draft	YES
3734217	23879987	UB	2	co-initiated the project and designed the research|developed the image processing algorithms for quantitative and longitudinal analysis of small animal images|wrote the software for all algorithms|prepared all figures and tables|designed a segmentation evaluation test for inter- and intra-operator variation derivation|conducted all statistical tests	prepared all figures and tables	-	Visualization	YES
3734217	23879987	UB	2	co-initiated the project and designed the research|developed the image processing algorithms for quantitative and longitudinal analysis of small animal images|wrote the software for all algorithms|prepared all figures and tables|designed a segmentation evaluation test for inter- and intra-operator variation derivation|conducted all statistical tests	designed a segmentation evaluation test for inter- and intra-operator variation derivation	Conceived and designed the experiments|Performed the experiments	Investigation	YES
3734217	23879987	UB	2	co-initiated the project and designed the research|developed the image processing algorithms for quantitative and longitudinal analysis of small animal images|wrote the software for all algorithms|prepared all figures and tables|designed a segmentation evaluation test for inter- and intra-operator variation derivation|conducted all statistical tests	conducted all statistical tests	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4409333	25909947	HN	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409333	25909947	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409333	25909947	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409333	25909947	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409333	25909947	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409333	25909947	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409333	25909947	SK	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4409333	25909947	SK	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4409333	25909947	SK	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409333	25909947	YM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4409333	25909947	YM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1766471	17245451	CO	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1766471	17245451	CO	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1766471	17245451	MO	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1766471	17245451	MO	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1766471	17245451	RO	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1766471	17245451	RO	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1766471	17245451	TK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1766471	17245451	TK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1766471	17245451	TK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1766471	17245451	TK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1766471	17245451	TK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1766471	17245451	TY	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1766471	17245451	TY	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
544894	15588328	BM	2	had implemented the mapping of expression data to pathways	had implemented the mapping of expression data to pathways	Performed the experiments	Investigation	YES
544894	15588328	DMS	2	has annotated the insulin signaling pathway	has annotated the insulin signaling pathway	-	-	NO
544894	15588328	GS	2	is involved in providing of sequence analysis tools and server software	is involved in providing of sequence analysis tools and server software	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources|Software	YES
544894	15588328	HH	2	was responsible for the content, the annotation process, webdesign, and processing of data sets	was responsible for the content, the annotation process, webdesign, and processing of data sets	Conceived and designed the experiments|Analyzed the data	Data curation|Formal analysis	YES
544894	15588328	JH	2	had implemented the mapping of expression data to pathways	had implemented the mapping of expression data to pathways	Performed the experiments	Investigation	YES
544894	15588328	MM	2	was responsible for the implementation of the database and web application as well as the relational database for the clone tracker	was responsible for the implementation of the database and web application as well as the relational database for the clone tracker	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
544894	15588328	ZT	2	was responsible for the design of the study and for overall project coordination	was responsible for the design of the study and for overall project coordination	Conceived and designed the experiments	Methodology|Project administration	YES
3737082	23915734	MFA	2	performed the experiments, analyzed and interpreted the data, and conceived and drafted the manuscript	performed the experiments, analyzed and interpreted the data, and conceived and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
3737082	23915734	MIMK	2	were involved in the conception of the manuscript, data interpretation, and manuscript writing	were involved in the conception of the manuscript, data interpretation, and manuscript writing	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
3737082	23915734	RS	2	were involved in the conception of the manuscript, data interpretation, and manuscript writing	were involved in the conception of the manuscript, data interpretation, and manuscript writing	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
3737082	23915734	SDK	2	contributed to data analysis and interpretation, to the conception of the manuscript, and to its writing	contributed to data analysis and interpretation, to the conception of the manuscript, and to its writing	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
6036396	29984473	LHN	2	inputs from other co-authors	inputs from other co-authors	-	-	NO
6036396	29984473	MK	2	drafted manuscript, with extensive feedback from other co-authors	drafted manuscript, with extensive feedback from other co-authors	Wrote the paper	Writing - Original Draft	YES
6036396	29984473	NF	2	inputs from other co-authors	inputs from other co-authors	-	-	NO
6036396	29984473	Y-RL	2	inputs from other co-authors	inputs from other co-authors	-	-	NO
5628244	29038660	AP	2	participated in performed the experiments	participated in performed the experiments	Performed the experiments	Investigation	YES
5628244	29038660	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5628244	29038660	GL	2	participated in the experimental design	participated in the experimental design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5628244	29038660	GX	2	participated in the experimental design	participated in the experimental design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5628244	29038660	JZ	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5628244	29038660	LH	2	participated in the experimental design	participated in the experimental design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5628244	29038660	ML	2	conceived the idea and participated in the interpretation of results and preparation of manuscript	conceived the idea and participated in the interpretation of results and preparation of manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
5628244	29038660	MS	2	performed the experiment, data analysis and prepared the manuscript	performed the experiment, data analysis and prepared the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5628244	29038660	XQ	2	participated in performed the experiments	participated in performed the experiments	Performed the experiments	Investigation	YES
5628244	29038660	XW	2	performed the experiment, data analysis and prepared the manuscript	performed the experiment, data analysis and prepared the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4409334	25909632	CJ	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409334	25909632	CJ	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409334	25909632	KL	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409334	25909632	KV	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409334	25909632	KV	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409334	25909632	SB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409334	25909632	SB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409334	25909632	SB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409334	25909632	SB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409334	25909632	ZL	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3737085	23915679	ABMAA	2	designed the experiments, contributed to the experimental analysis and interpretation of data, and contributed to the manuscript preparation|wrote the manuscript and revised the manuscript from other co-authors	designed the experiments, contributed to the experimental analysis and interpretation of data, and contributed to the manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
3737085	23915679	ABMAA	2	designed the experiments, contributed to the experimental analysis and interpretation of data, and contributed to the manuscript preparation|wrote the manuscript and revised the manuscript from other co-authors	wrote the manuscript and revised the manuscript from other co-authors	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3737085	23915679	GKR	2	designed the experiments, contributed to the interpretation of the experimental data, and edited the manuscript	designed the experiments, contributed to the interpretation of the experimental data, and edited the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Review & Editing	YES
3737085	23915679	JG	2	designed the experiments, contributed to the experimental analysis and interpretation of data, and contributed to the manuscript preparation	designed the experiments, contributed to the experimental analysis and interpretation of data, and contributed to the manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
3737085	23915679	PP	2	designed the experiments, contributed to the experimental analysis and interpretation of data, and contributed to the manuscript preparation|wrote the manuscript and revised the manuscript from other co-authors	designed the experiments, contributed to the experimental analysis and interpretation of data, and contributed to the manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
3737085	23915679	PP	2	designed the experiments, contributed to the experimental analysis and interpretation of data, and contributed to the manuscript preparation|wrote the manuscript and revised the manuscript from other co-authors	wrote the manuscript and revised the manuscript from other co-authors	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3737085	23915679	XG	2	conceived the work and contributed to the interpretation of the experimental data and editing the manuscript	conceived the work and contributed to the interpretation of the experimental data and editing the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Resources|Writing - Review & Editing	YES
1766472	17264880	BO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1766472	17264880	BO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1766472	17264880	BO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1766472	17264880	JR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1766472	17264880	JR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1766472	17264880	JR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1766472	17264880	PL	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1766472	17264880	RF	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1766472	17264880	RF	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3750402	23924517	AKK	2	contributed to the concept and design of the study|acquired data on the subjects|analyzed and interpreted the data	contributed to the concept and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3750402	23924517	AKK	2	contributed to the concept and design of the study|acquired data on the subjects|analyzed and interpreted the data	acquired data on the subjects	Performed the experiments	Investigation	YES
3750402	23924517	AKK	2	contributed to the concept and design of the study|acquired data on the subjects|analyzed and interpreted the data	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
3750402	23924517	All authors	2	contributed substantially to the scientific process leading to this manuscript	contributed substantially to the scientific process leading to this manuscript	-	-	NO
3750402	23924517	BJ	2	contributed to the concept and design of the study	contributed to the concept and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3750402	23924517	CWH	2	analyzed and interpreted the data	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
3750402	23924517	JTR	2	analyzed and interpreted the data	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
3750402	23924517	LF	2	analyzed and interpreted the data	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
3750402	23924517	MKN	2	acquired data on the subjects	acquired data on the subjects	Performed the experiments	Investigation	YES
3750402	23924517	MR	2	contributed to the concept and design of the study|analyzed and interpreted the data	contributed to the concept and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3750402	23924517	MR	2	contributed to the concept and design of the study|analyzed and interpreted the data	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
3750402	23924517	SSP	2	contributed to the concept and design of the study|acquired data on the subjects|analyzed and interpreted the data	contributed to the concept and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3750402	23924517	SSP	2	contributed to the concept and design of the study|acquired data on the subjects|analyzed and interpreted the data	acquired data on the subjects	Performed the experiments	Investigation	YES
3750402	23924517	SSP	2	contributed to the concept and design of the study|acquired data on the subjects|analyzed and interpreted the data	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
4409335	25909858	AMM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409335	25909858	AMM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409335	25909858	AMM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409335	25909858	AMM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409335	25909858	AMM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409335	25909858	AP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409335	25909858	AP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409335	25909858	AP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409335	25909858	AP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409335	25909858	BS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409335	25909858	BT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409335	25909858	BT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409335	25909858	BT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409335	25909858	BT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409335	25909858	CS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409335	25909858	CS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4409335	25909858	CS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409335	25909858	DW	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409335	25909858	DW	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409335	25909858	DW	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409335	25909858	MB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
544896	15610557	GJW	2	collaborated on bioinformatics and database development	collaborated on bioinformatics and database development	Contributed reagents/materials/analysis tools	Formal analysis|Software	YES
544896	15610557	JAW	2	provided microarray data and analyses	provided microarray data and analyses	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
544896	15610557	JP	2	designed, scripted and implemented funnybase and provided statistical analyses of database	designed, scripted and implemented funnybase and provided statistical analyses of database	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources|Software	YES
5630980	29038661	HB	2	concieved and designed the study and supervised all the analysis and drafted manuscript	concieved and designed the study and supervised all the analysis and drafted manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Original Draft	YES
5630980	29038661	HC	2	performed the analysis and drafted manuscript	performed the analysis and drafted manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5630980	29038661	SB	2	performed the analysis and drafted manuscript	performed the analysis and drafted manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4117108	25206017	ACPP	2	of 8	of 8	-	-	NO
6038000	29987877	AC	2	performed the elisa experiments|developed tools	performed the elisa experiments	Performed the experiments	Investigation	YES
6038000	29987877	AC	2	performed the elisa experiments|developed tools	developed tools	-	-	NO
6038000	29987877	All authors	2	participated in the analyses and interpretation of the data	participated in the analyses and interpretation of the data	Analyzed the data	Formal analysis	YES
6038000	29987877	BJ	2	performed the intestinal tissue preparations|wrote the animal protocols	performed the intestinal tissue preparations	Performed the experiments	Investigation	YES
6038000	29987877	BJ	2	performed the intestinal tissue preparations|wrote the animal protocols	wrote the animal protocols	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
6038000	29987877	CG	2	provided human samples	provided human samples	Contributed reagents/materials/analysis tools	Resources	YES
6038000	29987877	CL	2	provided human samples	provided human samples	Contributed reagents/materials/analysis tools	Resources	YES
6038000	29987877	DD	2	developed tools|developed the concept of the study and its experimental design	developed tools	-	-	NO
6038000	29987877	DD	2	developed tools|developed the concept of the study and its experimental design	developed the concept of the study and its experimental design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6038000	29987877	FB	2	performed data curation regarding samples from the human cohorts	performed data curation regarding samples from the human cohorts	Analyzed the data	Data curation	YES
6038000	29987877	LM	2	provided simian samples|performed data curation regarding samples from the human cohorts|supervised them	provided simian samples	Contributed reagents/materials/analysis tools	Resources	YES
6038000	29987877	LM	2	provided simian samples|performed data curation regarding samples from the human cohorts|supervised them	performed data curation regarding samples from the human cohorts	Analyzed the data	Data curation	YES
6038000	29987877	LM	2	provided simian samples|performed data curation regarding samples from the human cohorts|supervised them	supervised them	-	Supervision	YES
6038000	29987877	MA	2	developed the concept of the study and its experimental design	developed the concept of the study and its experimental design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6038000	29987877	MG	2	provided human samples|performed data curation regarding samples from the human cohorts	provided human samples	Contributed reagents/materials/analysis tools	Resources	YES
6038000	29987877	MG	2	provided human samples|performed data curation regarding samples from the human cohorts	performed data curation regarding samples from the human cohorts	Analyzed the data	Data curation	YES
6038000	29987877	MJP	2	performed the elisa experiments|performed the qpcr assays|performed the intestinal tissue preparations|developed the concept of the study and its experimental design|prepared the figures	performed the elisa experiments	Performed the experiments	Investigation	YES
6038000	29987877	MJP	2	performed the elisa experiments|performed the qpcr assays|performed the intestinal tissue preparations|developed the concept of the study and its experimental design|prepared the figures	performed the qpcr assays	Performed the experiments	Investigation	YES
6038000	29987877	MJP	2	performed the elisa experiments|performed the qpcr assays|performed the intestinal tissue preparations|developed the concept of the study and its experimental design|prepared the figures	performed the intestinal tissue preparations	Performed the experiments	Investigation	YES
6038000	29987877	MJP	2	performed the elisa experiments|performed the qpcr assays|performed the intestinal tissue preparations|developed the concept of the study and its experimental design|prepared the figures	developed the concept of the study and its experimental design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6038000	29987877	MJP	2	performed the elisa experiments|performed the qpcr assays|performed the intestinal tissue preparations|developed the concept of the study and its experimental design|prepared the figures	prepared the figures	-	Visualization	YES
6038000	29987877	MMT	2	developed the concept of the study and its experimental design|wrote the human protocols, supervised the research and wrote the manuscript, which was reviewed by the co-authors	developed the concept of the study and its experimental design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6038000	29987877	MMT	2	developed the concept of the study and its experimental design|wrote the human protocols, supervised the research and wrote the manuscript, which was reviewed by the co-authors	wrote the human protocols, supervised the research and wrote the manuscript, which was reviewed by the co-authors	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
6038000	29987877	MP	2	provided simian samples	provided simian samples	Contributed reagents/materials/analysis tools	Resources	YES
6038000	29987877	NH	2	performed the intestinal tissue preparations	performed the intestinal tissue preparations	Performed the experiments	Investigation	YES
6038000	29987877	NK	2	provided human samples|performed data curation regarding samples from the human cohorts	provided human samples	Contributed reagents/materials/analysis tools	Resources	YES
6038000	29987877	NK	2	provided human samples|performed data curation regarding samples from the human cohorts	performed data curation regarding samples from the human cohorts	Analyzed the data	Data curation	YES
6038000	29987877	NN	2	prepared the figures	prepared the figures	-	Visualization	YES
6038000	29987877	OL	2	provided human samples	provided human samples	Contributed reagents/materials/analysis tools	Resources	YES
6038000	29987877	RLG	2	provided simian samples	provided simian samples	Contributed reagents/materials/analysis tools	Resources	YES
6038000	29987877	SJP	2	performed the intestinal tissue preparations	performed the intestinal tissue preparations	Performed the experiments	Investigation	YES
6038000	29987877	TB	2	performed data curation regarding samples from the human cohorts	performed data curation regarding samples from the human cohorts	Analyzed the data	Data curation	YES
6038000	29987877	TGT	2	performed the intestinal tissue preparations	performed the intestinal tissue preparations	Performed the experiments	Investigation	YES
6038000	29987877	YM	2	prepared the figures	prepared the figures	-	Visualization	YES
1766473	17245443	EK	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1766473	17245443	EK	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1766473	17245443	FS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1766473	17245443	FS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1766473	17245443	HT	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1766473	17245443	HT	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1766473	17245443	HX	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1766473	17245443	HX	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1766473	17245443	JQ	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1766473	17245443	JQ	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1766473	17245443	KV	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1766473	17245443	KV	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1766473	17245443	LW	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Wrote the paper|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1766473	17245443	LW	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Wrote the paper|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1766473	17245443	LW	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Wrote the paper|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1766473	17245443	LW	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Wrote the paper|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1766473	17245443	LW	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Wrote the paper|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1766473	17245443	LW	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Wrote the paper|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1766473	17245443	LW	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Wrote the paper|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1766473	17245443	LW	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Wrote the paper|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1766473	17245443	MR	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1766473	17245443	MZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1766473	17245443	MZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1766473	17245443	MZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1766473	17245443	MZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1766473	17245443	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1766473	17245443	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1766473	17245443	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1766473	17245443	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1766473	17245443	XZ	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1766473	17245443	XZ	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
3750838	23915639	CC	2	helped considerably with the data analysis|have been involved significantly in data interpretation, drafting the manuscript and revising it critically for important intellectual content	helped considerably with the data analysis	Analyzed the data	Formal analysis	YES
3750838	23915639	CC	2	helped considerably with the data analysis|have been involved significantly in data interpretation, drafting the manuscript and revising it critically for important intellectual content	have been involved significantly in data interpretation, drafting the manuscript and revising it critically for important intellectual content	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
3750838	23915639	CMD	2	designed the study protocol|have been involved significantly in data interpretation, drafting the manuscript and revising it critically for important intellectual content	designed the study protocol	Conceived and designed the experiments	Methodology	YES
3750838	23915639	CMD	2	designed the study protocol|have been involved significantly in data interpretation, drafting the manuscript and revising it critically for important intellectual content	have been involved significantly in data interpretation, drafting the manuscript and revising it critically for important intellectual content	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
3750838	23915639	EL	2	coordinated and interpreted the histological and ihc examination of all resected prostate specimen|contributed to the draft of the manuscript	coordinated and interpreted the histological and ihc examination of all resected prostate specimen	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Project administration	YES
3750838	23915639	EL	2	coordinated and interpreted the histological and ihc examination of all resected prostate specimen|contributed to the draft of the manuscript	contributed to the draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
3750838	23915639	FC	2	acquired the anatomical images and defined the prostatic tissue compartments in the images|contributed to the draft of the manuscript	acquired the anatomical images and defined the prostatic tissue compartments in the images	Analyzed the data	Formal analysis|Visualization	YES
3750838	23915639	FC	2	acquired the anatomical images and defined the prostatic tissue compartments in the images|contributed to the draft of the manuscript	contributed to the draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
3750838	23915639	FMM	2	designed the study protocol|have been involved significantly in data interpretation, drafting the manuscript and revising it critically for important intellectual content	designed the study protocol	Conceived and designed the experiments	Methodology	YES
3750838	23915639	FMM	2	designed the study protocol|have been involved significantly in data interpretation, drafting the manuscript and revising it critically for important intellectual content	have been involved significantly in data interpretation, drafting the manuscript and revising it critically for important intellectual content	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
3750838	23915639	GMB	2	performed the tracer labelling|have been involved significantly in data interpretation, drafting the manuscript and revising it critically for important intellectual content	performed the tracer labelling	Performed the experiments	Investigation	YES
3750838	23915639	GMB	2	performed the tracer labelling|have been involved significantly in data interpretation, drafting the manuscript and revising it critically for important intellectual content	have been involved significantly in data interpretation, drafting the manuscript and revising it critically for important intellectual content	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
3750838	23915639	HD	2	helped with patient inclusion|contributed to the draft of the manuscript	helped with patient inclusion	-	-	NO
3750838	23915639	HD	2	helped with patient inclusion|contributed to the draft of the manuscript	contributed to the draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
3750838	23915639	HVP	2	helped with patient inclusion|contributed to the draft of the manuscript	helped with patient inclusion	-	-	NO
3750838	23915639	HVP	2	helped with patient inclusion|contributed to the draft of the manuscript	contributed to the draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
3750838	23915639	KG	2	have been involved significantly in data interpretation, drafting the manuscript and revising it critically for important intellectual content	have been involved significantly in data interpretation, drafting the manuscript and revising it critically for important intellectual content	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
3750838	23915639	KH	2	helped with patient inclusion|contributed to the draft of the manuscript	helped with patient inclusion	-	-	NO
3750838	23915639	KH	2	helped with patient inclusion|contributed to the draft of the manuscript	contributed to the draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
3750838	23915639	KME	2	conceived of and contributed to the study design, acquired all data, performed the data analysis and interpretation and drafted the manuscript	conceived of and contributed to the study design, acquired all data, performed the data analysis and interpretation and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
3750838	23915639	KVL	2	contributed substantially to the study design|have been involved significantly in data interpretation, drafting the manuscript and revising it critically for important intellectual content	contributed substantially to the study design	Conceived and designed the experiments	Methodology	YES
3750838	23915639	KVL	2	contributed substantially to the study design|have been involved significantly in data interpretation, drafting the manuscript and revising it critically for important intellectual content	have been involved significantly in data interpretation, drafting the manuscript and revising it critically for important intellectual content	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
3750838	23915639	LDW	2	acquired the anatomical images and defined the prostatic tissue compartments in the images|contributed to the draft of the manuscript	acquired the anatomical images and defined the prostatic tissue compartments in the images	Analyzed the data	Formal analysis|Visualization	YES
3750838	23915639	LDW	2	acquired the anatomical images and defined the prostatic tissue compartments in the images|contributed to the draft of the manuscript	contributed to the draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
3750838	23915639	LM	2	have been involved significantly in data interpretation, drafting the manuscript and revising it critically for important intellectual content	have been involved significantly in data interpretation, drafting the manuscript and revising it critically for important intellectual content	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
3750838	23915639	LVDB	2	helped with the screening of patients and coregistration of the ihc data with the anatomical images|contributed to the draft of the manuscript	helped with the screening of patients and coregistration of the ihc data with the anatomical images	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
3750838	23915639	LVDB	2	helped with the screening of patients and coregistration of the ihc data with the anatomical images|contributed to the draft of the manuscript	contributed to the draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
3750838	23915639	MK	2	contributed substantially to the study design|helped considerably with the data analysis|have been involved significantly in data interpretation, drafting the manuscript and revising it critically for important intellectual content	contributed substantially to the study design	Conceived and designed the experiments	Methodology	YES
3750838	23915639	MK	2	contributed substantially to the study design|helped considerably with the data analysis|have been involved significantly in data interpretation, drafting the manuscript and revising it critically for important intellectual content	helped considerably with the data analysis	Analyzed the data	Formal analysis	YES
3750838	23915639	MK	2	contributed substantially to the study design|helped considerably with the data analysis|have been involved significantly in data interpretation, drafting the manuscript and revising it critically for important intellectual content	have been involved significantly in data interpretation, drafting the manuscript and revising it critically for important intellectual content	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
3750838	23915639	SJ	2	helped with patient inclusion|contributed to the draft of the manuscript	helped with patient inclusion	-	-	NO
3750838	23915639	SJ	2	helped with patient inclusion|contributed to the draft of the manuscript	contributed to the draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
4409336	25909324	FSW	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409336	25909324	FSW	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409336	25909324	HJ	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409336	25909324	JY	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409336	25909324	JY	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409336	25909324	JY	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409336	25909324	LJW	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409336	25909324	LJW	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409336	25909324	QFW	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409336	25909324	XMZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409336	25909324	XMZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409336	25909324	XMZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409336	25909324	ZJY	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5632542	29042862	HP-O	2	optimized the membrane protein isolation protocol	optimized the membrane protein isolation protocol	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5632542	29042862	L-CC	2	prepared the materials for the nitrate starvation and resupply experiment	prepared the materials for the nitrate starvation and resupply experiment	Performed the experiments	Investigation	YES
5632542	29042862	LX	2	performed the data analysis manuscript revision and part of figure preparation	performed the data analysis manuscript revision and part of figure preparation	Analyzed the data|Wrote the paper	Formal analysis|Visualization|Writing - Original Draft|Writing - Review & Editing	YES
5632542	29042862	WS	2	provided experimental design	provided experimental design	Conceived and designed the experiments	Methodology	YES
5632542	29042862	XW	2	provided experimental design	provided experimental design	Conceived and designed the experiments	Methodology	YES
5632542	29042862	ZL	2	prepared the materials for the nitrate starvation and resupply experiment	prepared the materials for the nitrate starvation and resupply experiment	Performed the experiments	Investigation	YES
5450071	28558696	ACL	2	assisted in the paper preparation and results discussion	assisted in the paper preparation and results discussion	-	-	NO
5450071	28558696	ACM	2	developed the brazilian thematic maps and georeferenced the landraces	developed the brazilian thematic maps and georeferenced the landraces	-	-	NO
5450071	28558696	ASGC	2	assisted in the paper preparation and results discussion	assisted in the paper preparation and results discussion	-	-	NO
5450071	28558696	BSFM	2	made substantial contributions to the bioinformatics, genomic analysis and interpretation of data	made substantial contributions to the bioinformatics, genomic analysis and interpretation of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5450071	28558696	CB	2	assisted in the paper preparation and results discussion	assisted in the paper preparation and results discussion	-	-	NO
5450071	28558696	GRCC	2	prepared the dna samples	prepared the dna samples	Performed the experiments	Investigation	YES
5450071	28558696	IPPM	2	made substantial contributions to the bioinformatics, genomic analysis and interpretation of data	made substantial contributions to the bioinformatics, genomic analysis and interpretation of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5450071	28558696	JEAF	2	made substantial contributions to the bioinformatics, genomic analysis and interpretation of data	made substantial contributions to the bioinformatics, genomic analysis and interpretation of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5450071	28558696	JPGV	2	made substantial contributions to the bioinformatics, genomic analysis and interpretation of data	made substantial contributions to the bioinformatics, genomic analysis and interpretation of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5450071	28558696	JPO	2	assisted in the germplasm identification	assisted in the germplasm identification	Performed the experiments	Investigation	YES
5450071	28558696	MIZ	2	assisted in the paper preparation and results discussion	assisted in the paper preparation and results discussion	-	-	NO
5450071	28558696	PAMRV	2	conducted the analysis of the experiments, interpreted results and wrote the paper	conducted the analysis of the experiments, interpreted results and wrote the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5450071	28558696	RPV	2	coordinated the study, participated in analyzing data and wrote the paper	coordinated the study, participated in analyzing data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Project administration|Writing - Original Draft	YES
5450071	28558696	WJP	2	made substantial contributions to the bioinformatics, genomic analysis and interpretation of data	made substantial contributions to the bioinformatics, genomic analysis and interpretation of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
4539442	26346893	Hosik Choi	2	contributed equally to this work	contributed equally to this work	-	-	NO
4539442	26346893	Sungho Won	2	contributed equally to this work	contributed equally to this work	-	-	NO
1769464	17245449	BL	1	Participated in the statistical analysis of the study and interpretation of the results	Participated in the statistical analysis of the study and interpretation of the results	Analyzed the data	Formal analysis	YES
1769464	17245449	HG	1	Participated in the design of the study and interpretation of the results, and contributed to manuscript preparation	Participated in the design of the study and interpretation of the results, and contributed to manuscript preparation	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
1769464	17245449	JS	1	Contributed to the interpretation of the results and manuscript drafting	Contributed to the interpretation of the results and manuscript drafting	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
1769464	17245449	MB	1	Was involved in study design, interpretation of the results and writing of the manuscript	Was involved in study design, interpretation of the results and writing of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
1769464	17245449	MS	1	Participated in the statistical analysis of the study and interpretation of the results	Participated in the statistical analysis of the study and interpretation of the results	Analyzed the data	Formal analysis	YES
1769464	17245449	PS	1	Responsible for the design and statistical analysis of the cost-effectiveness analysis, interpretation of the results and wrote the first draft of the manuscript	Responsible for the design and statistical analysis of the cost-effectiveness analysis, interpretation of the results and wrote the first draft of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3751550	23870677	AH	2	carried out the autoradiography	carried out the autoradiography	Performed the experiments	Investigation	YES
3751550	23870677	JY	2	carried out the autoradiography	carried out the autoradiography	Performed the experiments	Investigation	YES
3751550	23870677	K Kawamura	2	performed the chemical synthesis, radiosynthesis, and measurement of lipophilicity	performed the chemical synthesis, radiosynthesis, and measurement of lipophilicity	Performed the experiments	Investigation	YES
3751550	23870677	K Kumata	2	performed the chemical synthesis, radiosynthesis, and measurement of lipophilicity	performed the chemical synthesis, radiosynthesis, and measurement of lipophilicity	Performed the experiments	Investigation	YES
3751550	23870677	KF	2	operated the automated machine for radiosynthesis	operated the automated machine for radiosynthesis	Performed the experiments	Investigation	YES
3751550	23870677	M-RZ	2	designed the present study and wrote the manuscript	designed the present study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3751550	23870677	MF	2	performed the chemical synthesis, radiosynthesis, and measurement of lipophilicity	performed the chemical synthesis, radiosynthesis, and measurement of lipophilicity	Performed the experiments	Investigation	YES
3751550	23870677	MO	2	operated the automated machine for radiosynthesis	operated the automated machine for radiosynthesis	Performed the experiments	Investigation	YES
3751550	23870677	NN	2	operated the automated machine for radiosynthesis	operated the automated machine for radiosynthesis	Performed the experiments	Investigation	YES
3751550	23870677	PET	2	experiments, and metabolite analyses	experiments, and metabolite analyses	Analyzed the data	Formal analysis	YES
3751550	23870677	TY	2	participated in all experiments and drafted the manuscript	participated in all experiments and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3751550	23870677	XL	2	carried out the autoradiography	carried out the autoradiography	Performed the experiments	Investigation	YES
6038147	29989338	HV	2	have contributed to the preparation of the manuscript, read and approved the final draft	have contributed to the preparation of the manuscript, read and approved the final draft	Wrote the paper	Writing - Original Draft	YES
6038147	29989338	KHM	2	have contributed to the preparation of the manuscript, read and approved the final draft	have contributed to the preparation of the manuscript, read and approved the final draft	Wrote the paper	Writing - Original Draft	YES
4409337	25909893	CPS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Approved the final version of the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409337	25909893	CPS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Approved the final version of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4409337	25909893	CPS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Approved the final version of the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409337	25909893	CPS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Approved the final version of the manuscript	Approved the final version of the manuscript	-	-	NO
4409337	25909893	DN	PLoS5	Performed the experiments|Approved the final version of the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4409337	25909893	DN	PLoS5	Performed the experiments|Approved the final version of the manuscript	Approved the final version of the manuscript	-	-	NO
4409337	25909893	EOF	PLoS5	Performed the experiments|Analyzed the data|Approved the final version of the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4409337	25909893	EOF	PLoS5	Performed the experiments|Analyzed the data|Approved the final version of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4409337	25909893	EOF	PLoS5	Performed the experiments|Analyzed the data|Approved the final version of the manuscript	Approved the final version of the manuscript	-	-	NO
4409337	25909893	GBE	PLoS5	Contributed reagents/materials/analysis tools|Approved the final version of the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409337	25909893	GBE	PLoS5	Contributed reagents/materials/analysis tools|Approved the final version of the manuscript	Approved the final version of the manuscript	-	-	NO
4409337	25909893	GR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409337	25909893	GR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4409337	25909893	GR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409337	25909893	JRMF	PLoS5	Performed the experiments|Approved the final version of the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4409337	25909893	JRMF	PLoS5	Performed the experiments|Approved the final version of the manuscript	Approved the final version of the manuscript	-	-	NO
4409337	25909893	KC	PLoS5	Contributed reagents/materials/analysis tools|Approved the final version of the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409337	25909893	KC	PLoS5	Contributed reagents/materials/analysis tools|Approved the final version of the manuscript	Approved the final version of the manuscript	-	-	NO
4409337	25909893	PCT	PLoS5	Contributed reagents/materials/analysis tools|Approved the final version of the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409337	25909893	PCT	PLoS5	Contributed reagents/materials/analysis tools|Approved the final version of the manuscript	Approved the final version of the manuscript	-	-	NO
4409337	25909893	RG	PLoS5	Approved the final version of the manuscript	Approved the final version of the manuscript	-	-	NO
4409337	25909893	VLS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Approved the final version of the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409337	25909893	VLS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Approved the final version of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4409337	25909893	VLS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Approved the final version of the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409337	25909893	VLS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Approved the final version of the manuscript	Approved the final version of the manuscript	-	-	NO
5632646	29046689	DW	2	provided guidance and help throughout this process as well as teaching and supervision|contributed equally to writing the manuscript	provided guidance and help throughout this process as well as teaching and supervision	-	Supervision	YES
5632646	29046689	DW	2	provided guidance and help throughout this process as well as teaching and supervision|contributed equally to writing the manuscript	contributed equally to writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5632646	29046689	JA	2	designed the described method, components and collected all images and data utilized in this manuscript|contributed equally to writing the manuscript	designed the described method, components and collected all images and data utilized in this manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Investigation|Methodology|Visualization	YES
5632646	29046689	JA	2	designed the described method, components and collected all images and data utilized in this manuscript|contributed equally to writing the manuscript	contributed equally to writing the manuscript	Wrote the paper	Writing - Original Draft	YES
1769465	17235363	AA	PLoS5	Conceived and designed the experiments|Leader	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1769465	17235363	AA	PLoS5	Conceived and designed the experiments|Leader	Leader	-	Supervision	YES
1769465	17235363	AP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1769465	17235363	AP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1769465	17235363	BS	PLoS5	Conceived and designed the experiments|Wrote the paper|Biopuces team	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1769465	17235363	BS	PLoS5	Conceived and designed the experiments|Wrote the paper|Biopuces team	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1769465	17235363	BS	PLoS5	Conceived and designed the experiments|Wrote the paper|Biopuces team	Biopuces team	-	-	NO
1769465	17235363	CD	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1769465	17235363	CL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1769465	17235363	CL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1769465	17235363	CM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1769465	17235363	CM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1769465	17235363	FC	PLoS5	Conceived and designed the experiments|Leader	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1769465	17235363	FC	PLoS5	Conceived and designed the experiments|Leader	Leader	-	Supervision	YES
1769465	17235363	FL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1769465	17235363	FL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1769465	17235363	FL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1769465	17235363	FL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1769465	17235363	FL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1769465	17235363	HP	PLoS5	Conceived and designed the experiments|Platform management	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1769465	17235363	HP	PLoS5	Conceived and designed the experiments|Platform management	Platform management	-	-	NO
1769465	17235363	JA	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1769465	17235363	JA	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1769465	17235363	JR	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1769465	17235363	JR	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
6041569	29998619	CW	2	co-wrote this paper	co-wrote this paper	Wrote the paper	Writing - Original Draft	YES
6041569	29998619	HFR	2	co-wrote this paper	co-wrote this paper	Wrote the paper	Writing - Original Draft	YES
3751570	23947784	HL	2	participated in the design of the study and in the analysis and interpretation of data	participated in the design of the study and in the analysis and interpretation of data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
3751570	23947784	KS	2	carried out the analysis of data	carried out the analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3751570	23947784	LE	2	participated in the design of the study and in the analysis and interpretation of data, and drafted the manuscript	participated in the design of the study and in the analysis and interpretation of data, and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3751570	23947784	ML	2	participated in the design of the study and in the analysis and interpretation of data	participated in the design of the study and in the analysis and interpretation of data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
3751570	23947784	MO	2	carried out the analysis of data	carried out the analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3751570	23947784	PG	2	participated in the design of the study and in the analysis and interpretation of data	participated in the design of the study and in the analysis and interpretation of data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
3751570	23947784	RK	2	participated in the design of the study and in the analysis and interpretation of data, and drafted the manuscript	participated in the design of the study and in the analysis and interpretation of data, and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4409338	25909591	JJ	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409338	25909591	KL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409338	25909591	KX	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409338	25909591	KX	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409338	25909591	KX	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409338	25909591	MB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409338	25909591	MB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409338	25909591	MB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409338	25909591	SL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409338	25909591	SL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409338	25909591	SL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409338	25909591	WY	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409338	25909591	YB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409338	25909591	YW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409338	25909591	YW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409338	25909591	YW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409338	25909591	YX	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5632647	29046678	AI	2	jointly conceived the study, acquired and interpreted the data, wrote the manuscript and assisted with manuscript revision	jointly conceived the study, acquired and interpreted the data, wrote the manuscript and assisted with manuscript revision	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5632647	29046678	AN	2	acquired and analyzed data and commented on the manuscript	acquired and analyzed data and commented on the manuscript	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5632647	29046678	MM	2	jointly conceived the study, interpreted the data, commented on the results	jointly conceived the study, interpreted the data, commented on the results	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
5632647	29046678	PD	2	assisted with data interpretation, manuscript writing, commented, reviewed and submitted the manuscript	assisted with data interpretation, manuscript writing, commented, reviewed and submitted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5632647	29046678	SL	2	acquired and analyzed data and commented on the manuscript	acquired and analyzed data and commented on the manuscript	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5450074	28558796	BHT	2	conceived the study, participated in experimental design and works and critically reviewed the drafted manuscript	conceived the study, participated in experimental design and works and critically reviewed the drafted manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5450074	28558796	BT	2	analyzed results of the microarray data|contributed other bioinformatics analysis, interpreted the data, and drafted the manuscript	analyzed results of the microarray data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5450074	28558796	BT	2	analyzed results of the microarray data|contributed other bioinformatics analysis, interpreted the data, and drafted the manuscript	contributed other bioinformatics analysis, interpreted the data, and drafted the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
5450074	28558796	CH	2	analyzed results of the microarray data	analyzed results of the microarray data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5450074	28558796	MZM	2	performed experimental procedures involving viruses and hybridizations	performed experimental procedures involving viruses and hybridizations	Performed the experiments	Investigation	YES
5450074	28558796	RJS	2	conceived the study, participated in experimental design and works and critically reviewed the drafted manuscript	conceived the study, participated in experimental design and works and critically reviewed the drafted manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5450074	28558796	SMS	2	helped in data analysis, drafting and critical review of the manuscript	helped in data analysis, drafting and critical review of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
1769466	17268575	AP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1769466	17268575	AP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1769466	17268575	AP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1769466	17268575	AP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1769466	17268575	DC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1769466	17268575	DC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1769466	17268575	DC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1769466	17268575	ID	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1769466	17268575	ID	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1769466	17268575	KY	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1769466	17268575	KY	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1769466	17268575	MR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1769466	17268575	MR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1769466	17268575	MR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1769466	17268575	RL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1769466	17268575	RL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1769466	17268575	RL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1769466	17268575	RL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3751692	23938036	ATMW	PLoS52	participated in the design of the study and revised the manuscript	participated in the design of the study and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
3751692	23938036	EHdG	PLoS52	analyzed the data, performed the statistical analysis and drafted the manuscript	analyzed the data, performed the statistical analysis and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3751692	23938036	JAvD	PLoS52	designed the study, performed the statistical analysis and revised the manuscript	designed the study, performed the statistical analysis and revised the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
3751692	23938036	NP	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
3751692	23938036	NRLW	PLoS52	provided the patient data	provided the patient data	Contributed reagents/materials/analysis tools	Resources	YES
3751692	23938036	RB	PLoS52	designed and performed the simulations	designed and performed the simulations	Conceived and designed the experiments|Performed the experiments	Formal analysis|Investigation	YES
3772744	23561423	EL	2	conceived the model analysis, participated in the study design and coordination, and in the manuscript writing	conceived the model analysis, participated in the study design and coordination, and in the manuscript writing	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
3772744	23561423	JB	2	participated in the study design, in the model interpretation and in the manuscript writing	participated in the study design, in the model interpretation and in the manuscript writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3772744	23561423	MB	2	participated in the study design, in the model interpretation and in the manuscript writing	participated in the study design, in the model interpretation and in the manuscript writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3772744	23561423	RM	2	participated in the study design, in the model interpretation and in the manuscript writing	participated in the study design, in the model interpretation and in the manuscript writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4409339	25909846	AH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409339	25909846	AH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409339	25909846	AH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409339	25909846	AH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409339	25909846	AH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409339	25909846	CB	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409339	25909846	CB	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409339	25909846	CB	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409339	25909846	MV	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409339	25909846	MV	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409339	25909846	PP	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409339	25909846	RDR	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409339	25909846	RDR	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409339	25909846	RDR	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6053474	30027643	AT	2	assisted with the literature review and revised and reviewed manuscript drafts	assisted with the literature review and revised and reviewed manuscript drafts	Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
6053474	30027643	GH	2	led in the design of the qualitative cohort and supported the analysis and content of this manuscript	led in the design of the qualitative cohort and supported the analysis and content of this manuscript	Conceived and designed the experiments	-	YES
6053474	30027643	HA	2	designed the hptn071 intervention and have oversight of all research activities	designed the hptn071 intervention and have oversight of all research activities	Conceived and designed the experiments	Methodology|Supervision	YES
6053474	30027643	JS	2	gave technical support to the qualitative cohort at all stages and supported the analysis approach and editing for this manuscript	gave technical support to the qualitative cohort at all stages and supported the analysis approach and editing for this manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
6053474	30027643	MS	2	was involved in the qualitative cohort data collection process, conducted and wrote up earlier data on the same community and reviewed the content of this manuscript	was involved in the qualitative cohort data collection process, conducted and wrote up earlier data on the same community and reviewed the content of this manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
6053474	30027643	RH	2	designed the hptn071 intervention and have oversight of all research activities	designed the hptn071 intervention and have oversight of all research activities	Conceived and designed the experiments	Methodology|Supervision	YES
6053474	30027643	SF	2	designed the hptn071 intervention and have oversight of all research activities	designed the hptn071 intervention and have oversight of all research activities	Conceived and designed the experiments	Methodology|Supervision	YES
5632652	29046682	Both authors	2	have made a substantial, direct and intellectual contribution to the work, and approved it for publication	have made a substantial, direct and intellectual contribution to the work, and approved it for publication	-	-	NO
5450082	28558729	AC	2	designed the study|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5450082	28558729	AC	2	designed the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5450082	28558729	AS	2	designed and performed assays and contributed to their analysis	designed and performed assays and contributed to their analysis	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5450082	28558729	HSC	2	designed the study|analyzed data|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5450082	28558729	HSC	2	designed the study|analyzed data|wrote the manuscript	analyzed data	Analyzed the data	Formal analysis	YES
5450082	28558729	HSC	2	designed the study|analyzed data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5450082	28558729	MB	2	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5450082	28558729	MRM	2	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5450082	28558729	PS	2	designed the study|analyzed data|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5450082	28558729	PS	2	designed the study|analyzed data|wrote the manuscript	analyzed data	Analyzed the data	Formal analysis	YES
5450082	28558729	PS	2	designed the study|analyzed data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5450082	28558729	TRG	2	designed and performed assays and contributed to their analysis	designed and performed assays and contributed to their analysis	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5450082	28558729	XY	2	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
1769520	17225866	AD	PLoS5	Contributed reagents/materials/analysis tools|Contributed conceptually and edited the manuscript text	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1769520	17225866	AD	PLoS5	Contributed reagents/materials/analysis tools|Contributed conceptually and edited the manuscript text	Contributed conceptually and edited the manuscript text	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
1769520	17225866	JD	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Conceived the study, wrote the code for the stochastic simulations, contributed conceptually and edited the manuscript text	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1769520	17225866	JD	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Conceived the study, wrote the code for the stochastic simulations, contributed conceptually and edited the manuscript text	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1769520	17225866	JD	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Conceived the study, wrote the code for the stochastic simulations, contributed conceptually and edited the manuscript text	Conceived the study, wrote the code for the stochastic simulations, contributed conceptually and edited the manuscript text	Conceived and designed the experiments|Wrote the paper	Conceptualization|Formal analysis|Software|Writing - Original Draft|Writing - Review & Editing	YES
1769520	17225866	JP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Conceived the study, analyzed the deterministic model, wrote the code for the stochastic simulations, parameterized the model for diseases in human populations, contributed conceptually and edited the manuscript text	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1769520	17225866	JP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Conceived the study, analyzed the deterministic model, wrote the code for the stochastic simulations, parameterized the model for diseases in human populations, contributed conceptually and edited the manuscript text	Performed the experiments	Performed the experiments	Investigation	YES
1769520	17225866	JP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Conceived the study, analyzed the deterministic model, wrote the code for the stochastic simulations, parameterized the model for diseases in human populations, contributed conceptually and edited the manuscript text	Analyzed the data	Analyzed the data	Formal analysis	YES
1769520	17225866	JP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Conceived the study, analyzed the deterministic model, wrote the code for the stochastic simulations, parameterized the model for diseases in human populations, contributed conceptually and edited the manuscript text	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1769520	17225866	JP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Conceived the study, analyzed the deterministic model, wrote the code for the stochastic simulations, parameterized the model for diseases in human populations, contributed conceptually and edited the manuscript text	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1769520	17225866	JP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Conceived the study, analyzed the deterministic model, wrote the code for the stochastic simulations, parameterized the model for diseases in human populations, contributed conceptually and edited the manuscript text	Conceived the study, analyzed the deterministic model, wrote the code for the stochastic simulations, parameterized the model for diseases in human populations, contributed conceptually and edited the manuscript text	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Software|Writing - Original Draft|Writing - Review & Editing	YES
1769520	17225866	SL	PLoS5	Contributed reagents/materials/analysis tools|Analyzed the deterministic model, contributed conceptually and edited the manuscript text	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1769520	17225866	SL	PLoS5	Contributed reagents/materials/analysis tools|Analyzed the deterministic model, contributed conceptually and edited the manuscript text	Analyzed the deterministic model, contributed conceptually and edited the manuscript text	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
3818979	24165377	AG	2	provided the pet scanner and the financial support and guidance in the design of the experiment, as well as the insightful and important revisions to the manuscript	provided the pet scanner and the financial support and guidance in the design of the experiment, as well as the insightful and important revisions to the manuscript	Conceived and designed the experiments|Wrote the paper	Funding acquisition|Methodology|Supervision|Writing - Review & Editing	YES
3818979	24165377	BX	2	also developed and carried out mr imaging sequences and supervised the wet-lab studies	also developed and carried out mr imaging sequences and supervised the wet-lab studies	Performed the experiments|Analyzed the data	Investigation|Supervision|Visualization	YES
3818979	24165377	CC	2	handled the animal models, carried out surgeries to create the heart failure models, the stem cell injection, and provided animal care	handled the animal models, carried out surgeries to create the heart failure models, the stem cell injection, and provided animal care	Performed the experiments	Investigation|Methodology	YES
3818979	24165377	CHIR	2	design of the experiments, and materials and laboratory resources and did the revisions of the manuscript	design of the experiments, and materials and laboratory resources and did the revisions of the manuscript	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Methodology|Resources|Writing - Review & Editing	YES
3818979	24165377	DF	2	provided advice on the experimental design	provided advice on the experimental design	Conceived and designed the experiments	Methodology	YES
3818979	24165377	EE	2	is the corresponding author|designed, drafted, and revised the manuscript, coordinated the experiments, carried out the pet imaging data acquisition, and was involved in pet data analysis and results	is the corresponding author	-	-	NO
3818979	24165377	EE	2	is the corresponding author|designed, drafted, and revised the manuscript, coordinated the experiments, carried out the pet imaging data acquisition, and was involved in pet data analysis and results	designed, drafted, and revised the manuscript, coordinated the experiments, carried out the pet imaging data acquisition, and was involved in pet data analysis and results	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Project administration|Visualization|Writing - Original Draft|Writing - Review & Editing	YES
3818979	24165377	FDG	2	carried out pet image analysis, developed pet-mer image registration software, and created the figures and tables|pcr measurements, data analysis, histochemical analysis, and provision of microscopic pictures	carried out pet image analysis, developed pet-mer image registration software, and created the figures and tables	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Investigation|Software|Visualization	YES
3818979	24165377	FDG	2	carried out pet image analysis, developed pet-mer image registration software, and created the figures and tables|pcr measurements, data analysis, histochemical analysis, and provision of microscopic pictures	pcr measurements, data analysis, histochemical analysis, and provision of microscopic pictures	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
3818979	24165377	FW	2	handled the animal models, carried out surgeries to create the heart failure models, the stem cell injection, and provided animal care	handled the animal models, carried out surgeries to create the heart failure models, the stem cell injection, and provided animal care	Performed the experiments	Investigation|Methodology	YES
3818979	24165377	RA	2	provided insightful advice on the experimental design, revisions to the manuscript, and general knowledge contribution to the stem cell studies	provided insightful advice on the experimental design, revisions to the manuscript, and general knowledge contribution to the stem cell studies	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Methodology|Resources|Writing - Review & Editing	YES
3818979	24165377	SM	2	provided the fdg, radiochemistry support, advice on the experimental design, and revisions to the manuscript	provided the fdg, radiochemistry support, advice on the experimental design, and revisions to the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
3818979	24165377	SPIO	2	pcr measurements, data analysis, histochemical analysis, and provision of microscopic pictures	pcr measurements, data analysis, histochemical analysis, and provision of microscopic pictures	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
3818979	24165377	Team Grant	2	design of the experiments, and materials and laboratory resources and did the revisions of the manuscript	design of the experiments, and materials and laboratory resources and did the revisions of the manuscript	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Methodology|Resources|Writing - Review & Editing	YES
3828419	24219987	CR	2	designed and carried out the in vitro experiments, performed the analysis of the results and drafted the manuscript	designed and carried out the in vitro experiments, performed the analysis of the results and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
3828419	24219987	JWB	2	made a substantial contribution to the conception, design and organisation of the conduct of the study	made a substantial contribution to the conception, design and organisation of the conduct of the study	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
3828419	24219987	MB	2	made a substantial contribution to the conception, design and organisation of the conduct of the study	made a substantial contribution to the conception, design and organisation of the conduct of the study	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
3828419	24219987	MT	2	carried out the xenograft experiments and performed the analysis of the results	carried out the xenograft experiments and performed the analysis of the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3828419	24219987	RJM	2	contributed to the design, supervision, and preparation of the manuscript	contributed to the design, supervision, and preparation of the manuscript	Conceived and designed the experiments|Wrote the paper	Supervision|Writing - Original Draft	YES
5450132	28558690	IM	PLoS52	performed the bioinformatics analyses|analysed the data|wrote the paper	performed the bioinformatics analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5450132	28558690	IM	PLoS52	performed the bioinformatics analyses|analysed the data|wrote the paper	analysed the data	Analyzed the data	Formal analysis	YES
5450132	28558690	IM	PLoS52	performed the bioinformatics analyses|analysed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5450132	28558690	PX	PLoS52	collected the data|performed the additional validations	collected the data	Performed the experiments	Investigation	YES
5450132	28558690	PX	PLoS52	collected the data|performed the additional validations	performed the additional validations	Performed the experiments	Investigation|Validation	YES
5450132	28558690	RC	PLoS52	designed the experiment|analysed the data|wrote the paper	designed the experiment	Conceived and designed the experiments	Methodology	YES
5450132	28558690	RC	PLoS52	designed the experiment|analysed the data|wrote the paper	analysed the data	Analyzed the data	Formal analysis	YES
5450132	28558690	RC	PLoS52	designed the experiment|analysed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5450132	28558690	SO	PLoS52	designed the experiment|collected the data|performed the bioinformatics analyses|performed the additional validations|analysed the data|wrote the paper	designed the experiment	Conceived and designed the experiments	Methodology	YES
5450132	28558690	SO	PLoS52	designed the experiment|collected the data|performed the bioinformatics analyses|performed the additional validations|analysed the data|wrote the paper	collected the data	Performed the experiments	Investigation	YES
5450132	28558690	SO	PLoS52	designed the experiment|collected the data|performed the bioinformatics analyses|performed the additional validations|analysed the data|wrote the paper	performed the bioinformatics analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5450132	28558690	SO	PLoS52	designed the experiment|collected the data|performed the bioinformatics analyses|performed the additional validations|analysed the data|wrote the paper	performed the additional validations	Performed the experiments	Investigation|Validation	YES
5450132	28558690	SO	PLoS52	designed the experiment|collected the data|performed the bioinformatics analyses|performed the additional validations|analysed the data|wrote the paper	analysed the data	Analyzed the data	Formal analysis	YES
5450132	28558690	SO	PLoS52	designed the experiment|collected the data|performed the bioinformatics analyses|performed the additional validations|analysed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5450132	28558690	TD	PLoS52	analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
5632664	29046688	The authors	2	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	Performed the experiments	Investigation	YES
5632664	29046688	YE	2	coordinated the project	coordinated the project	-	Project administration	YES
5632664	29046688	YL	2	conceived this study, performed data analyses, and wrote the manuscript	conceived this study, performed data analyses, and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
4409340	25909956	JHY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409340	25909956	JHY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409340	25909956	JHY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409340	25909956	JHY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409340	25909956	JHY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409340	25909956	LHP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409340	25909956	LHP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409340	25909956	LHP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409340	25909956	LHP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3831261	24225195	EM	2	implemented the analysis methods, analysed the data, participated in the design of the study and conceived and drafted the manuscript	implemented the analysis methods, analysed the data, participated in the design of the study and conceived and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
3831261	24225195	JTD	2	contributed to the design of the study and the interpretation of the data, as well as in the review of the manuscript	contributed to the design of the study and the interpretation of the data, as well as in the review of the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Review & Editing	YES
3831261	24225195	MV	2	participated in the implementation of the analysis methods and in the analysis data, as well as in the manuscript writing	participated in the implementation of the analysis methods and in the analysis data, as well as in the manuscript writing	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3831261	24225195	PJB	2	was involved in the interpretation of the data and in the manuscript review	was involved in the interpretation of the data and in the manuscript review	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
3831261	24225195	RAM	2	designed and carried out the perfusion experiments and participated in the critical review of the manuscript	designed and carried out the perfusion experiments and participated in the critical review of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
3831261	24225195	RS	2	designed and carried out the perfusion experiments and participated in the critical review of the manuscript	designed and carried out the perfusion experiments and participated in the critical review of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
3831261	24225195	TRE	2	designed the study and was involved in the data analysis as well as in the review of the manuscript	designed the study and was involved in the data analysis as well as in the review of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
4409341	25910171	EHS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409341	25910171	EJC	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4409341	25910171	EJC	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409341	25910171	EJL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409341	25910171	IGB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409341	25910171	JBJ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409341	25910171	JWC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409341	25910171	MHJ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409341	25910171	MSL	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409341	25910171	SRL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409341	25910171	SYM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409341	25910171	SYP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409341	25910171	YPC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409341	25910171	YPC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409341	25910171	YPC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409341	25910171	YSK	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409341	25910171	YSK	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5632726	29046683	CF	2	designed the experiments|discussed the results and modified the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5632726	29046683	CF	2	designed the experiments|discussed the results and modified the manuscript	discussed the results and modified the manuscript	Wrote the paper	Writing - Review & Editing	YES
5632726	29046683	FH	2	discussed the results and modified the manuscript	discussed the results and modified the manuscript	Wrote the paper	Writing - Review & Editing	YES
5632726	29046683	RW	2	discussed the results and modified the manuscript	discussed the results and modified the manuscript	Wrote the paper	Writing - Review & Editing	YES
5632726	29046683	SL	2	discussed the results and modified the manuscript	discussed the results and modified the manuscript	Wrote the paper	Writing - Review & Editing	YES
5632726	29046683	XZ	2	discussed the results and modified the manuscript	discussed the results and modified the manuscript	Wrote the paper	Writing - Review & Editing	YES
5632726	29046683	YC	2	discussed the results and modified the manuscript	discussed the results and modified the manuscript	Wrote the paper	Writing - Review & Editing	YES
5632726	29046683	YZ	2	designed the experiments|conducted the study, processed the data and wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5632726	29046683	YZ	2	designed the experiments|conducted the study, processed the data and wrote the manuscript	conducted the study, processed the data and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Investigation|Writing - Original Draft	YES
5632726	29046683	ZH	2	designed the experiments|discussed the results and modified the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5632726	29046683	ZH	2	designed the experiments|discussed the results and modified the manuscript	discussed the results and modified the manuscript	Wrote the paper	Writing - Review & Editing	YES
5450142	28558694	IB	2	designed and performed the experiments, interpreted the results and wrote the manuscript	designed and performed the experiments, interpreted the results and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5450142	28558694	MF	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5450142	28558694	NL	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5450142	28558694	PK	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5450142	28558694	SHO	2	designed methodology for rna seq data analysis and wrote the manuscript	designed methodology for rna seq data analysis and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5450142	28558694	TW	2	prepared the bac for sequencing	prepared the bac for sequencing	Performed the experiments	Investigation	YES
1770952	17245445	BK	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1770952	17245445	RF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1770952	17245445	RF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1770952	17245445	RF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1770952	17245445	RF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1770952	17245445	RF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6053476	30027668	AA	2	conducted the statistical analysis|secondary responsibility for writing the manuscript	conducted the statistical analysis	Analyzed the data	Formal analysis	YES
6053476	30027668	AA	2	conducted the statistical analysis|secondary responsibility for writing the manuscript	secondary responsibility for writing the manuscript	Wrote the paper	Writing - Original Draft	YES
6053476	30027668	All authors	2	were involved in review, critiquing and editing of the manuscript	were involved in review, critiquing and editing of the manuscript	Wrote the paper	Writing - Review & Editing	YES
6053476	30027668	CSC	2	conducted the statistical analysis	conducted the statistical analysis	Analyzed the data	Formal analysis	YES
6053476	30027668	EDC	2	secondary responsibility for writing the manuscript	secondary responsibility for writing the manuscript	Wrote the paper	Writing - Original Draft	YES
6053476	30027668	IM	2	oversaw data collection and curation	oversaw data collection and curation	Performed the experiments|Analyzed the data	Data curation|Investigation|Supervision	YES
6053476	30027668	MG	2	contributed to data analysis and interpretation|oversaw data collection and curation	contributed to data analysis and interpretation	Analyzed the data	Formal analysis	YES
6053476	30027668	MG	2	contributed to data analysis and interpretation|oversaw data collection and curation	oversaw data collection and curation	Performed the experiments|Analyzed the data	Data curation|Investigation|Supervision	YES
6053476	30027668	PE	2	oversaw data collection and curation	oversaw data collection and curation	Performed the experiments|Analyzed the data	Data curation|Investigation|Supervision	YES
6053476	30027668	TBN	2	contributed to data analysis and interpretation	contributed to data analysis and interpretation	Analyzed the data	Formal analysis	YES
3834104	24238306	HI	2	supervised the design and coordination of the study	supervised the design and coordination of the study	Conceived and designed the experiments	Methodology|Project administration|Supervision	YES
3834104	24238306	HShimada	2	participated in clinical pet study and contributed to the discussion	participated in clinical pet study and contributed to the discussion	-	-	NO
3834104	24238306	HShinotoh	2	participated in clinical pet study and contributed to the discussion	participated in clinical pet study and contributed to the discussion	-	-	NO
3834104	24238306	KF	2	conceived of the study, participated in the simulation study, and helped to draft the manuscript	conceived of the study, participated in the simulation study, and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
3834104	24238306	KS	2	participated in clinical pet study and the simulation study, and drafted the manuscript	participated in clinical pet study and the simulation study, and drafted the manuscript	Wrote the paper	Formal analysis|Writing - Original Draft	YES
3834104	24238306	NT	2	participated in clinical pet study and contributed to the discussion	participated in clinical pet study and contributed to the discussion	-	-	NO
3834104	24238306	SH	2	participated in clinical pet study and contributed to the discussion	participated in clinical pet study and contributed to the discussion	-	-	NO
3834104	24238306	TI	2	supervised the design and coordination of the study	supervised the design and coordination of the study	Conceived and designed the experiments	Methodology|Project administration|Supervision	YES
3834104	24238306	TS	2	supervised the design and coordination of the study	supervised the design and coordination of the study	Conceived and designed the experiments	Methodology|Project administration|Supervision	YES
4409342	25909779	AC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409342	25909779	AC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409342	25909779	AC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409342	25909779	AC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409342	25909779	AC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409342	25909779	ET	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409342	25909779	ET	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409342	25909779	ET	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409342	25909779	ET	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409342	25909779	ET	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409342	25909779	LP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409342	25909779	LP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409342	25909779	LP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409342	25909779	LP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409342	25909779	LP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5632728	29046684	EZ	2	determined the protein content	determined the protein content	Performed the experiments	Investigation	YES
5632728	29046684	FX	2	designed the experiments and critically revised the paper	designed the experiments and critically revised the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5632728	29046684	LR	2	accomplished the rna extraction and rt-qpcr analysis	accomplished the rna extraction and rt-qpcr analysis	Performed the experiments	Investigation	YES
5632728	29046684	XC	2	analyzed the data and wrote the paper	analyzed the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5632728	29046684	XY	2	supervised the experiments	supervised the experiments	-	Supervision	YES
5632728	29046684	YY	2	performed resin slicing and drew the figures	performed resin slicing and drew the figures	Performed the experiments	Investigation|Visualization	YES
5632728	29046684	ZD	2	collected the experimental samples and materials	collected the experimental samples and materials	Performed the experiments	Investigation	YES
3847228	24028474	DW	2	participated in the study design and manuscript drafting	participated in the study design and manuscript drafting	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3847228	24028474	FM	2	participated in the pet exams and image analysis	participated in the pet exams and image analysis	Analyzed the data	Visualization	YES
3847228	24028474	GK	2	participated in the study design and manuscript drafting	participated in the study design and manuscript drafting	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3847228	24028474	HB	2	participated in the pet exams and image analysis	participated in the pet exams and image analysis	Analyzed the data	Visualization	YES
3847228	24028474	JZ	2	participated in the ex vivo experiments	participated in the ex vivo experiments	Performed the experiments	Investigation	YES
3847228	24028474	MB	2	performed the animal experiments and participated in the data analysis and manuscript drafting	performed the animal experiments and participated in the data analysis and manuscript drafting	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3847228	24028474	PYM	2	supervised the study and drafted the manuscript	supervised the study and drafted the manuscript	Wrote the paper	Supervision|Writing - Original Draft	YES
3847228	24028474	RF	2	performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
3847228	24028474	SP	2	participated in the pet exams and image analysis	participated in the pet exams and image analysis	Analyzed the data	Visualization	YES
3847228	24028474	YD	2	supervised the study and drafted the manuscript	supervised the study and drafted the manuscript	Wrote the paper	Supervision|Writing - Original Draft	YES
5450186	28558688	AK	2	wrote and edited the manuscript, with	wrote and edited the manuscript, with	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5450186	28558688	EST-SSR	2	discovery and queried the repeat databases	discovery and queried the repeat databases	Contributed reagents/materials/analysis tools	Software	YES
5450186	28558688	JEC	2	supervised the larger project as a whole	supervised the larger project as a whole	-	Supervision	YES
5450186	28558688	JMK	2	did the parentage analysis that revealed that sm2 was the predominant pollen parent for sm1	did the parentage analysis that revealed that sm2 was the predominant pollen parent for sm1	-	-	NO
5450186	28558688	JRS	2	wrote and edited the manuscript, with|conceived, designed, and directed the project	wrote and edited the manuscript, with	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5450186	28558688	JRS	2	wrote and edited the manuscript, with|conceived, designed, and directed the project	conceived, designed, and directed the project	Conceived and designed the experiments	Conceptualization|Methodology|Supervision	YES
5450186	28558688	MTS	2	did the ddradseq library preps and size selections	did the ddradseq library preps and size selections	-	-	NO
5450186	28558688	MVC	2	verified the species identity of the parents, accomplished the clonal replication of the parents and progeny, established the clonal orchard and collected, prepared and submitted the voucher specimens	verified the species identity of the parents, accomplished the clonal replication of the parents and progeny, established the clonal orchard and collected, prepared and submitted the voucher specimens	Performed the experiments	Investigation|Validation	YES
5450186	28558688	OC	2	constructed the ddradseq bioinformatics pipeline, designed downsampling experiments and did the downsampling|wrote and edited the manuscript, with	constructed the ddradseq bioinformatics pipeline, designed downsampling experiments and did the downsampling	Conceived and designed the experiments|Performed the experiments	Formal analysis|Investigation|Methodology	YES
5450186	28558688	OC	2	constructed the ddradseq bioinformatics pipeline, designed downsampling experiments and did the downsampling|wrote and edited the manuscript, with	wrote and edited the manuscript, with	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5450186	28558688	OG	2	assisted with the with	assisted with the with	-	-	NO
5450186	28558688	RADseq	2	calls and final map construction	calls and final map construction	Performed the experiments	Investigation	YES
5450186	28558688	SE	2	constructed the ddradseq bioinformatics pipeline, designed downsampling experiments and did the downsampling	constructed the ddradseq bioinformatics pipeline, designed downsampling experiments and did the downsampling	Conceived and designed the experiments|Performed the experiments	Formal analysis|Investigation|Methodology	YES
5450186	28558688	SNP	2	calls and final map construction	calls and final map construction	Performed the experiments	Investigation	YES
5450186	28558688	SS	2	hosted the mapping populations	hosted the mapping populations	-	-	NO
6053477	30027687	AT	2	supported drafting the introduction	supported drafting the introduction	Wrote the paper	Writing - Original Draft	YES
6053477	30027687	All co-authors	2	participated in the interpretation of data and reviewing the manuscript at different stages	participated in the interpretation of data and reviewing the manuscript at different stages	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
6053477	30027687	GH	2	led the design of the qualitative cohort data collection process, supervised the analytic team, and led the drafting of this manuscript	led the design of the qualitative cohort data collection process, supervised the analytic team, and led the drafting of this manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Formal analysis|Investigation|Supervision|Writing - Original Draft	YES
6053477	30027687	HM	2	participated in data collection, led the analysis of observational data, and supported the development of the conceptual heuristic	participated in data collection, led the analysis of observational data, and supported the development of the conceptual heuristic	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation	YES
6053477	30027687	JM	2	participated in data collection and led the analysis of interview/discussion data	participated in data collection and led the analysis of interview/discussion data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6053477	30027687	LR	2	supported the design of the qualitative cohort data collection process, offered expert oversight for the analytic design and conceptualization of this paper, and provided detailed revisions of the paper itself	supported the design of the qualitative cohort data collection process, offered expert oversight for the analytic design and conceptualization of this paper, and provided detailed revisions of the paper itself	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Data curation|Formal analysis|Investigation|Supervision|Writing - Review & Editing	YES
6053477	30027687	LdV	2	participated in data collection and led the analysis of interview/discussion data	participated in data collection and led the analysis of interview/discussion data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6053477	30027687	MM	2	participated in data collection and led the analysis of interview/discussion data	participated in data collection and led the analysis of interview/discussion data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6053477	30027687	RN	2	participated in data collection and led the analysis of interview/discussion data	participated in data collection and led the analysis of interview/discussion data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
1773017	17264884	FW	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1773017	17264884	JX	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1773017	17264884	LT	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1773017	17264884	MJ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1773017	17264884	MJ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1773017	17264884	MJ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1773017	17264884	SL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1773017	17264884	SL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1773017	17264884	SL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1773017	17264884	XY	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1773017	17264884	XZ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1773017	17264884	XZ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1773017	17264884	XZ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409343	25909659	APS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4409343	25909659	APS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409343	25909659	FDC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409343	25909659	FDC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409343	25909659	FJZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409343	25909659	FJZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409343	25909659	FJZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409343	25909659	FJZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409343	25909659	HBW	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4409343	25909659	HBW	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409343	25909659	LLH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409343	25909659	NJT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409343	25909659	NJT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409343	25909659	NJT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409343	25909659	NJT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409343	25909659	WD	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409343	25909659	WMF	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409343	25909659	WMF	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
3848680	24041012	FDG	2	uptake studies, human tumor xenografts establishment, immunohistochemistry and drafted the manuscript	uptake studies, human tumor xenografts establishment, immunohistochemistry and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3848680	24041012	FDG-PET	2	imaging, data acquisition and analysis	imaging, data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
3848680	24041012	JT	2	participated in the study design and coordination	participated in the study design and coordination	Conceived and designed the experiments	Methodology|Project administration	YES
3848680	24041012	LiL	2	assisted with in vitro and ex - vivo studies	assisted with in vitro and ex - vivo studies	Performed the experiments	Investigation	YES
3848680	24041012	LuL	2	participated in the study design and coordination	participated in the study design and coordination	Conceived and designed the experiments	Methodology|Project administration	YES
3848680	24041012	NH	2	participated in the study design and coordination	participated in the study design and coordination	Conceived and designed the experiments	Methodology|Project administration	YES
3848680	24041012	NI	2	participated in the study design and coordination	participated in the study design and coordination	Conceived and designed the experiments	Methodology|Project administration	YES
3848680	24041012	PP	2	participated in the study design and coordination	participated in the study design and coordination	Conceived and designed the experiments	Methodology|Project administration	YES
3848680	24041012	SOP	2	of xenografts experiments	of xenografts experiments	-	-	NO
3848680	24041012	SSE	2	participated in the study design and coordination	participated in the study design and coordination	Conceived and designed the experiments	Methodology|Project administration	YES
3848680	24041012	VM	2	participated in the study design and coordination	participated in the study design and coordination	Conceived and designed the experiments	Methodology|Project administration	YES
4543116	26345295	Despina Moissidou	2	all contributed equally to this work	all contributed equally to this work	-	-	NO
4543116	26345295	Dong Hoon Shin	2	all contributed equally to this work	all contributed equally to this work	-	-	NO
4543116	26345295	Jasmine Day	2	all contributed equally to this work	all contributed equally to this work	-	-	NO
4543116	26345295	Raffaella Bianucci	2	all contributed equally to this work	all contributed equally to this work	-	-	NO
5853271	29568436	A.B.	2	created the website for public release of the database	created the website for public release of the database	Contributed reagents/materials/analysis tools	Software	YES
5853271	29568436	D.J.O.	2	performed the dtims instrumental analyses	performed the dtims instrumental analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5853271	29568436	E.S.B.	2	designed the experiments, analyzed the data and wrote the manuscript|determined the samples needed for the experiments, supervised different aspects of the project, and edited the manuscript	designed the experiments, analyzed the data and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5853271	29568436	E.S.B.	2	designed the experiments, analyzed the data and wrote the manuscript|determined the samples needed for the experiments, supervised different aspects of the project, and edited the manuscript	determined the samples needed for the experiments, supervised different aspects of the project, and edited the manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
5853271	29568436	N.A.A.	2	prepared the samples	prepared the samples	Performed the experiments	Investigation	YES
5853271	29568436	R.D.S.	2	determined the samples needed for the experiments, supervised different aspects of the project, and edited the manuscript	determined the samples needed for the experiments, supervised different aspects of the project, and edited the manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
5853271	29568436	R.W.	2	created the website for public release of the database	created the website for public release of the database	Contributed reagents/materials/analysis tools	Software	YES
5853271	29568436	S.H.P.	2	created the website for public release of the database	created the website for public release of the database	Contributed reagents/materials/analysis tools	Software	YES
5853271	29568436	X.Z.	2	designed the experiments, analyzed the data and wrote the manuscript|prepared the samples|performed the dtims instrumental analyses	designed the experiments, analyzed the data and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5853271	29568436	X.Z.	2	designed the experiments, analyzed the data and wrote the manuscript|prepared the samples|performed the dtims instrumental analyses	prepared the samples	Performed the experiments	Investigation	YES
5853271	29568436	X.Z.	2	designed the experiments, analyzed the data and wrote the manuscript|prepared the samples|performed the dtims instrumental analyses	performed the dtims instrumental analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5853271	29568436	Y.Z.	2	prepared the samples	prepared the samples	Performed the experiments	Investigation	YES
5632729	29046685	JP	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5632729	29046685	JP	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5632729	29046685	LL	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5632729	29046685	QX	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5632729	29046685	SZ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5632729	29046685	WL	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5632729	29046685	XD	PLoS52	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5632729	29046685	ZN	PLoS52	performed the experiments|analyzed the data|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5632729	29046685	ZN	PLoS52	performed the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5632729	29046685	ZN	PLoS52	performed the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3848786	24034278	DS	2	carried out the study concept and design, analyzed and interpreted the data, and wrote the manuscript	carried out the study concept and design, analyzed and interpreted the data, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
3848786	24034278	FDV	2	coordinated and revised the manuscript	coordinated and revised the manuscript	Wrote the paper	Project administration|Writing - Review & Editing	YES
1779620	17264883	EI	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1779620	17264883	EI	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1779620	17264883	EI	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1779620	17264883	GA	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1779620	17264883	GA	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1779620	17264883	GA	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1779620	17264883	GK	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1779620	17264883	GK	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1779620	17264883	IE	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1779620	17264883	IE	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1779620	17264883	IE	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1779620	17264883	JK	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1779620	17264883	JK	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1779620	17264883	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1779620	17264883	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1779620	17264883	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1779620	17264883	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1779620	17264883	JS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1779620	17264883	JS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1779620	17264883	JS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1779620	17264883	JS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1779620	17264883	JT	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1779620	17264883	JT	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1779620	17264883	JV	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1779620	17264883	JV	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1779620	17264883	KN	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1779620	17264883	KN	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1779620	17264883	MK	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1779620	17264883	MK	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1779620	17264883	MM	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1779620	17264883	MM	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1779620	17264883	PH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1779620	17264883	PH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1779620	17264883	PH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1779620	17264883	SV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1779620	17264883	SV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1779620	17264883	SV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1779620	17264883	SV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1779620	17264883	TT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1779620	17264883	TT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1779620	17264883	TT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409344	25909327	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409344	25909327	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4409344	25909327	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409344	25909327	FK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409344	25909327	FK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409344	25909327	FK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409344	25909327	FK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409344	25909327	JR	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409344	25909327	JR	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409344	25909327	KCN	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409344	25909327	KCN	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409344	25909327	MS	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409344	25909327	MS	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5632730	29046679	AG	2	conceived and designed the research|contributed in manuscript proofreading	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5632730	29046679	AG	2	conceived and designed the research|contributed in manuscript proofreading	contributed in manuscript proofreading	-	-	NO
5632730	29046679	AT	2	has contributed in bioinformatic analysis	has contributed in bioinformatic analysis	-	Formal analysis	YES
5632730	29046679	HM	2	contributed in tissue culture	contributed in tissue culture	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5632730	29046679	JB	2	has contributed in bioinformatic analysis	has contributed in bioinformatic analysis	-	Formal analysis	YES
5632730	29046679	PP	2	contributed in data analysis	contributed in data analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5632730	29046679	PY	2	contributed in data analysis	contributed in data analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5632730	29046679	RM	2	contributed in tissue culture	contributed in tissue culture	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5632730	29046679	SA	2	has performed all the experiments and wrote the manuscript	has performed all the experiments and wrote the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5632730	29046679	SR	2	contributed in tissue culture	contributed in tissue culture	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5632730	29046679	ZM	2	contributed in data analysis	contributed in data analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
3849131	24041035	CRF	2	performed the micropet analysis	performed the micropet analysis	Performed the experiments	Investigation	YES
3849131	24041035	HS	2	developed and carried out the organic syntheses and radiochemical syntheses and composed the manuscript	developed and carried out the organic syntheses and radiochemical syntheses and composed the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3849131	24041035	TB	2	performed the radiochemical syntheses	performed the radiochemical syntheses	Performed the experiments	Investigation	YES
3849131	24041035	TLR	2	is the project leader and coordinator	is the project leader and coordinator	-	Project administration|Supervision	YES
5450240	28558704	A.J.S.	2	provided guidance and consultation on the genotyping and biomarker details about adni data, data preprocessing, quality control, population stratification, gwas protocol, gene analysis, network analysis and pathway analysis	provided guidance and consultation on the genotyping and biomarker details about adni data, data preprocessing, quality control, population stratification, gwas protocol, gene analysis, network analysis and pathway analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Formal analysis|Investigation|Methodology|Resources|Supervision|Validation	YES
5450240	28558704	All the authors	2	reviewed, commented and approved the manuscript	reviewed, commented and approved the manuscript	Wrote the paper	Writing - Review & Editing	YES
5450240	28558704	CSF	2	biomarker data, and performed quality control and gwas	biomarker data, and performed quality control and gwas	Performed the experiments	Data curation|Investigation|Validation	YES
5450240	28558704	H.L.	2	led and supervised the research|designed the research and wrote the article	led and supervised the research	-	Supervision	YES
5450240	28558704	H.L.	2	led and supervised the research|designed the research and wrote the article	designed the research and wrote the article	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5450240	28558704	J.L.	2	led and supervised the research|designed the research and wrote the article	led and supervised the research	-	Supervision	YES
5450240	28558704	J.L.	2	led and supervised the research|designed the research and wrote the article	designed the research and wrote the article	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5450240	28558704	J.Y.	2	provided guidance and consultation on the genotyping and biomarker details about adni data, data preprocessing, quality control, population stratification, gwas protocol, gene analysis, network analysis and pathway analysis	provided guidance and consultation on the genotyping and biomarker details about adni data, data preprocessing, quality control, population stratification, gwas protocol, gene analysis, network analysis and pathway analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Formal analysis|Investigation|Methodology|Resources|Supervision|Validation	YES
5450240	28558704	L.S.	2	led and supervised the research|designed the research and wrote the article|provided guidance and consultation on the genotyping and biomarker details about adni data, data preprocessing, quality control, population stratification, gwas protocol, gene analysis, network analysis and pathway analysis	led and supervised the research	-	Supervision	YES
5450240	28558704	L.S.	2	led and supervised the research|designed the research and wrote the article|provided guidance and consultation on the genotyping and biomarker details about adni data, data preprocessing, quality control, population stratification, gwas protocol, gene analysis, network analysis and pathway analysis	designed the research and wrote the article	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5450240	28558704	L.S.	2	led and supervised the research|designed the research and wrote the article|provided guidance and consultation on the genotyping and biomarker details about adni data, data preprocessing, quality control, population stratification, gwas protocol, gene analysis, network analysis and pathway analysis	provided guidance and consultation on the genotyping and biomarker details about adni data, data preprocessing, quality control, population stratification, gwas protocol, gene analysis, network analysis and pathway analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Formal analysis|Investigation|Methodology|Resources|Supervision|Validation	YES
5450240	28558704	PINBPA	2	analysis, and pathway analysis	analysis, and pathway analysis	-	-	NO
5450240	28558704	S.C.	2	helped with research design and data analysis	helped with research design and data analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis	YES
5450240	28558704	S.K.	2	provided guidance and consultation on the genotyping and biomarker details about adni data, data preprocessing, quality control, population stratification, gwas protocol, gene analysis, network analysis and pathway analysis	provided guidance and consultation on the genotyping and biomarker details about adni data, data preprocessing, quality control, population stratification, gwas protocol, gene analysis, network analysis and pathway analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Formal analysis|Investigation|Methodology|Resources|Supervision|Validation	YES
5450240	28558704	W.C.	2	led and supervised the research|designed the research and wrote the article	led and supervised the research	-	Supervision	YES
5450240	28558704	W.C.	2	led and supervised the research|designed the research and wrote the article	designed the research and wrote the article	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5450240	28558704	W.L.	2	helped with research design and data analysis	helped with research design and data analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis	YES
5450240	28558704	X.M.	2	designed the research and wrote the article	designed the research and wrote the article	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5450240	28558704	X.Y.	2	provided guidance and consultation on the genotyping and biomarker details about adni data, data preprocessing, quality control, population stratification, gwas protocol, gene analysis, network analysis and pathway analysis	provided guidance and consultation on the genotyping and biomarker details about adni data, data preprocessing, quality control, population stratification, gwas protocol, gene analysis, network analysis and pathway analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Formal analysis|Investigation|Methodology|Resources|Supervision|Validation	YES
5450240	28558704	Y.W.	2	helped with research design and data analysis	helped with research design and data analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis	YES
6053480	30027600	All authors	2	contributed to the interpretation and presentation of the findings	contributed to the interpretation and presentation of the findings	Analyzed the data	Formal analysis	YES
6053480	30027600	JL	2	developed the research question addressed in this paper|did the statistical analysis|wrote the first draft of the manuscript with the support of jog	developed the research question addressed in this paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
6053480	30027600	JL	2	developed the research question addressed in this paper|did the statistical analysis|wrote the first draft of the manuscript with the support of jog	did the statistical analysis	Analyzed the data	Formal analysis	YES
6053480	30027600	JL	2	developed the research question addressed in this paper|did the statistical analysis|wrote the first draft of the manuscript with the support of jog	wrote the first draft of the manuscript with the support of jog	Wrote the paper	Writing - Original Draft	YES
6053480	30027600	JOG	2	developed the research question addressed in this paper	developed the research question addressed in this paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
6053480	30027600	MHD	2	did the statistical analysis	did the statistical analysis	Analyzed the data	Formal analysis	YES
6053480	30027600	NM	2	developed the research question addressed in this paper	developed the research question addressed in this paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4409345	25909712	AT	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409345	25909712	AV	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the software used in analysis	Performed the experiments	Performed the experiments	Investigation	YES
4409345	25909712	AV	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the software used in analysis	Analyzed the data	Analyzed the data	Formal analysis	YES
4409345	25909712	AV	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the software used in analysis	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409345	25909712	AV	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the software used in analysis	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409345	25909712	AV	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the software used in analysis	Designed the software used in analysis	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
4409345	25909712	LI	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409345	25909712	MS	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409345	25909712	MvD	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409345	25909712	PEVdB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the software used in analysis	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409345	25909712	PEVdB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the software used in analysis	Performed the experiments	Performed the experiments	Investigation	YES
4409345	25909712	PEVdB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the software used in analysis	Analyzed the data	Analyzed the data	Formal analysis	YES
4409345	25909712	PEVdB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the software used in analysis	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409345	25909712	PEVdB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the software used in analysis	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409345	25909712	PEVdB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the software used in analysis	Designed the software used in analysis	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
4409345	25909712	TS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the software used in analysis	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409345	25909712	TS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the software used in analysis	Performed the experiments	Performed the experiments	Investigation	YES
4409345	25909712	TS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the software used in analysis	Analyzed the data	Analyzed the data	Formal analysis	YES
4409345	25909712	TS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the software used in analysis	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409345	25909712	TS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the software used in analysis	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409345	25909712	TS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the software used in analysis	Designed the software used in analysis	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
4543372	26345612	Martina Haase	2	contributed equally to this work	contributed equally to this work	-	-	NO
4543372	26345612	Wolfgang Eichhorn	2	contributed equally to this work	contributed equally to this work	-	-	NO
3852759	24103360	AA	2	operated the micropet scanner and performed the imaging acquisition	operated the micropet scanner and performed the imaging acquisition	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
3852759	24103360	MAB	2	oversaw and coordinated the entirety of the project	oversaw and coordinated the entirety of the project	-	Project administration|Supervision	YES
3852759	24103360	MC	2	performed the immunocytochemistry assays and quantification	performed the immunocytochemistry assays and quantification	Performed the experiments	Investigation	YES
3852759	24103360	MJP	2	participated in imaging acquisition and immunocytochemistry preparation, performed all analyses, and drafted the manuscript	participated in imaging acquisition and immunocytochemistry preparation, performed all analyses, and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Visualization|Writing - Original Draft	YES
3852759	24103360	NM	2	performed the immunocytochemistry assays and quantification	performed the immunocytochemistry assays and quantification	Performed the experiments	Investigation	YES
3852759	24103360	PRN	2	contributed to the imaging pretreatment and analysis	contributed to the imaging pretreatment and analysis	Analyzed the data	Visualization	YES
5632738	29046687	All authors	2	listed have made a substantial, direct and intellectual contribution to the work, and approved it for publication	listed have made a substantial, direct and intellectual contribution to the work, and approved it for publication	-	-	NO
1779621	17268576	AD	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1779621	17268576	AD	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1779621	17268576	AN	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1779621	17268576	AN	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1779621	17268576	BB	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1779621	17268576	BB	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1779621	17268576	BB	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1779621	17268576	DM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1779621	17268576	DM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1779621	17268576	DM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1779621	17268576	DM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1779621	17268576	DP	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1779621	17268576	DP	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1779621	17268576	DP	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1779621	17268576	EC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1779621	17268576	EC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1779621	17268576	EC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1779621	17268576	EM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1779621	17268576	EM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1779621	17268576	EM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1779621	17268576	JV	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1779621	17268576	JV	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1779621	17268576	JW	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1779621	17268576	JW	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1779621	17268576	KD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1779621	17268576	KD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1779621	17268576	KD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1779621	17268576	KD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1779621	17268576	KJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Lead investigator and coordinated all study sites	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1779621	17268576	KJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Lead investigator and coordinated all study sites	Performed the experiments	Performed the experiments	Investigation	YES
1779621	17268576	KJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Lead investigator and coordinated all study sites	Analyzed the data	Analyzed the data	Formal analysis	YES
1779621	17268576	KJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Lead investigator and coordinated all study sites	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1779621	17268576	KJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Lead investigator and coordinated all study sites	Lead investigator and coordinated all study sites	-	Project administration	YES
1779621	17268576	KK	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1779621	17268576	KK	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1779621	17268576	MH	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1779621	17268576	MH	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1779621	17268576	PC	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1779621	17268576	PC	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1779621	17268576	PK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1779621	17268576	PK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1779621	17268576	PK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1779621	17268576	PP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1779621	17268576	PP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1779621	17268576	PP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1779621	17268576	PP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1779621	17268576	PS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1779621	17268576	PS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1779621	17268576	PS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1779621	17268576	PS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1779621	17268576	SP	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1779621	17268576	SP	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1779621	17268576	SS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1779621	17268576	SS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1779621	17268576	TS	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1779621	17268576	TS	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1779621	17268576	TS	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409346	25909458	BD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409346	25909458	BD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409346	25909458	BD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409346	25909458	BD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409346	25909458	BD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409346	25909458	CM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409346	25909458	CM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409346	25909458	CM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409346	25909458	CM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409346	25909458	CM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409346	25909458	MZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409346	25909458	MZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409346	25909458	MZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409346	25909458	MZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409346	25909458	MZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3853769	24139528	ASE	2	revised the manuscript critically for important intellectual content	revised the manuscript critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
3853769	24139528	CF	2	collected the data and drafted the manuscript	collected the data and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3853769	24139528	GH	2	contributed to the acquisition of funding and was part of the conception and design of the study	contributed to the acquisition of funding and was part of the conception and design of the study	Conceived and designed the experiments	Conceptualization|Funding acquisition|Methodology	YES
3853769	24139528	HA	2	was part of the conception and design of the study	was part of the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3853769	24139528	HH	2	collected the data and drafted the manuscript	collected the data and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3853769	24139528	IGS	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
3853769	24139528	JR	2	collected the data and revised the manuscript critically for important intellectual content	collected the data and revised the manuscript critically for important intellectual content	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
3853769	24139528	PH	2	collected the data, initiated the conception and design of the study, and revised the manuscript critically for important intellectual content	collected the data, initiated the conception and design of the study, and revised the manuscript critically for important intellectual content	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Writing - Review & Editing	YES
3853769	24139528	SS	2	collected data and revised the manuscript critically for important intellectual content	collected data and revised the manuscript critically for important intellectual content	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
6053481	30027686	AC	2	were also involved in analysis interpretation and contributed to the discussion and conclusions|also provided statistical support	were also involved in analysis interpretation and contributed to the discussion and conclusions	Analyzed the data	Formal analysis	YES
6053481	30027686	AC	2	were also involved in analysis interpretation and contributed to the discussion and conclusions|also provided statistical support	also provided statistical support	Analyzed the data	Formal analysis	YES
6053481	30027686	All authors	2	contributors in acknowledgements section were involved in data collection and exchange|contributed to the design of the study, commented on the manuscript and approved the final draft	contributors in acknowledgements section were involved in data collection and exchange	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
6053481	30027686	All authors	2	contributors in acknowledgements section were involved in data collection and exchange|contributed to the design of the study, commented on the manuscript and approved the final draft	contributed to the design of the study, commented on the manuscript and approved the final draft	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
6053481	30027686	FB	2	initiated this project|were also involved in analysis interpretation and contributed to the discussion and conclusions	initiated this project	Conceived and designed the experiments	Conceptualization	YES
6053481	30027686	FB	2	initiated this project|were also involved in analysis interpretation and contributed to the discussion and conclusions	were also involved in analysis interpretation and contributed to the discussion and conclusions	Analyzed the data	Formal analysis	YES
6053481	30027686	IF	2	carried out the data analyses and drafted the initial manuscript	carried out the data analyses and drafted the initial manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6053481	30027686	JDA	2	initiated this project|were also involved in analysis interpretation and contributed to the discussion and conclusions	initiated this project	Conceived and designed the experiments	Conceptualization	YES
6053481	30027686	JDA	2	initiated this project|were also involved in analysis interpretation and contributed to the discussion and conclusions	were also involved in analysis interpretation and contributed to the discussion and conclusions	Analyzed the data	Formal analysis	YES
1779622	17264887	CG	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1779622	17264887	DM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1779622	17264887	DM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1779622	17264887	DM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1779622	17264887	DM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1779622	17264887	EG	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1779622	17264887	EG	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1779622	17264887	EK	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1779622	17264887	EK	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1779622	17264887	KM	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1779622	17264887	KM	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5632739	29046686	CB	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5632739	29046686	CD	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5632739	29046686	XK	2	wrote the manuscript|performed all experiments	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5632739	29046686	XK	2	wrote the manuscript|performed all experiments	performed all experiments	Performed the experiments	Investigation	YES
5450241	28558659	AM	2	helped to conceive of the project, co-wrote manuscript, and provided advice and support throughout this project	helped to conceive of the project, co-wrote manuscript, and provided advice and support throughout this project	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5450241	28558659	EL	2	performed all experimental procedures and analyses of the rna seq data and wrote the manuscript	performed all experimental procedures and analyses of the rna seq data and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5450241	28558659	RH	2	helped conceive of this project and provided advice and support throughout much of this project	helped conceive of this project and provided advice and support throughout much of this project	Conceived and designed the experiments	Conceptualization	YES
3875899	24088510	AJS	2	were involved in the study design and interpretation of results	were involved in the study design and interpretation of results	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
3875899	24088510	AL	2	was involved in the acquisition and analysis of microdialysis data	was involved in the acquisition and analysis of microdialysis data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3875899	24088510	KD	2	helped design and run the study	helped design and run the study	Conceived and designed the experiments	Methodology	YES
3875899	24088510	MJF	2	were involved in the study design and interpretation of results	were involved in the study design and interpretation of results	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
3875899	24088510	MW	2	was involved in the study design and the acquisition, analysis, and interpretation of all data, and wrote the manuscript	was involved in the study design and the acquisition, analysis, and interpretation of all data, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
3875899	24088510	RK	2	advised on the study design, carried out the surgeries, and was involved in all data acquisition	advised on the study design, carried out the surgeries, and was involved in all data acquisition	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3875899	24088510	VS	2	were involved in the study design and interpretation of results	were involved in the study design and interpretation of results	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
1779623	17264888	JM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1779623	17264888	JM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1779623	17264888	JM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1779623	17264888	JM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1779623	17264888	YB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1779623	17264888	YB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1779623	17264888	YB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1779623	17264888	YB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6053482	30027583	AZ	2	contributed to the study design and manuscript writing	contributed to the study design and manuscript writing	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
6053482	30027583	CO	2	contributed to the study design and manuscript writing	contributed to the study design and manuscript writing	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
6053482	30027583	EJA	2	contributed to the study design and manuscript writing	contributed to the study design and manuscript writing	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
6053482	30027583	KC	2	contributed to the study design and analysis	contributed to the study design and analysis	Conceived and designed the experiments	Methodology	YES
6053482	30027583	LM	2	contributed to the study design and manuscript writing	contributed to the study design and manuscript writing	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
6053482	30027583	TP	2	conceived the design, conducted the analysis and drafted the manuscript	conceived the design, conducted the analysis and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
4409347	25909472	CG	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Interpretation of data|Drafting the article or revising it critically for important intellectual content|Final approval of the version to be published	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409347	25909472	CG	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Interpretation of data|Drafting the article or revising it critically for important intellectual content|Final approval of the version to be published	Performed the experiments	Performed the experiments	Investigation	YES
4409347	25909472	CG	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Interpretation of data|Drafting the article or revising it critically for important intellectual content|Final approval of the version to be published	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409347	25909472	CG	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Interpretation of data|Drafting the article or revising it critically for important intellectual content|Final approval of the version to be published	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409347	25909472	CG	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Interpretation of data|Drafting the article or revising it critically for important intellectual content|Final approval of the version to be published	Interpretation of data	Analyzed the data	Formal analysis	YES
4409347	25909472	CG	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Interpretation of data|Drafting the article or revising it critically for important intellectual content|Final approval of the version to be published	Drafting the article or revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4409347	25909472	CG	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Interpretation of data|Drafting the article or revising it critically for important intellectual content|Final approval of the version to be published	Final approval of the version to be published	-	-	NO
4409347	25909472	CJS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Interpretation of data|Drafting the article or revising it critically for important intellectual content|Final approval of the version to be published	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409347	25909472	CJS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Interpretation of data|Drafting the article or revising it critically for important intellectual content|Final approval of the version to be published	Analyzed the data	Analyzed the data	Formal analysis	YES
4409347	25909472	CJS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Interpretation of data|Drafting the article or revising it critically for important intellectual content|Final approval of the version to be published	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409347	25909472	CJS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Interpretation of data|Drafting the article or revising it critically for important intellectual content|Final approval of the version to be published	Interpretation of data	Analyzed the data	Formal analysis	YES
4409347	25909472	CJS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Interpretation of data|Drafting the article or revising it critically for important intellectual content|Final approval of the version to be published	Drafting the article or revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4409347	25909472	CJS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Interpretation of data|Drafting the article or revising it critically for important intellectual content|Final approval of the version to be published	Final approval of the version to be published	-	-	NO
4409347	25909472	EJR	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Interpretation of data|Drafting the article or revising it critically for important intellectual content|Final approval of the version to be published	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409347	25909472	EJR	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Interpretation of data|Drafting the article or revising it critically for important intellectual content|Final approval of the version to be published	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409347	25909472	EJR	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Interpretation of data|Drafting the article or revising it critically for important intellectual content|Final approval of the version to be published	Interpretation of data	Analyzed the data	Formal analysis	YES
4409347	25909472	EJR	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Interpretation of data|Drafting the article or revising it critically for important intellectual content|Final approval of the version to be published	Drafting the article or revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4409347	25909472	EJR	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Interpretation of data|Drafting the article or revising it critically for important intellectual content|Final approval of the version to be published	Final approval of the version to be published	-	-	NO
4409347	25909472	FP	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Interpretation of data|Drafting the article or revising it critically for important intellectual content|Final approval of the version to be published	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409347	25909472	FP	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Interpretation of data|Drafting the article or revising it critically for important intellectual content|Final approval of the version to be published	Performed the experiments	Performed the experiments	Investigation	YES
4409347	25909472	FP	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Interpretation of data|Drafting the article or revising it critically for important intellectual content|Final approval of the version to be published	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409347	25909472	FP	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Interpretation of data|Drafting the article or revising it critically for important intellectual content|Final approval of the version to be published	Interpretation of data	Analyzed the data	Formal analysis	YES
4409347	25909472	FP	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Interpretation of data|Drafting the article or revising it critically for important intellectual content|Final approval of the version to be published	Drafting the article or revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4409347	25909472	FP	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Interpretation of data|Drafting the article or revising it critically for important intellectual content|Final approval of the version to be published	Final approval of the version to be published	-	-	NO
4409347	25909472	HR	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Interpretation of data|Drafting the article or revising it critically for important intellectual content|Final approval of the version to be published	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409347	25909472	HR	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Interpretation of data|Drafting the article or revising it critically for important intellectual content|Final approval of the version to be published	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409347	25909472	HR	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Interpretation of data|Drafting the article or revising it critically for important intellectual content|Final approval of the version to be published	Interpretation of data	Analyzed the data	Formal analysis	YES
4409347	25909472	HR	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Interpretation of data|Drafting the article or revising it critically for important intellectual content|Final approval of the version to be published	Drafting the article or revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4409347	25909472	HR	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Interpretation of data|Drafting the article or revising it critically for important intellectual content|Final approval of the version to be published	Final approval of the version to be published	-	-	NO
4409347	25909472	JSB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Interpretation of data|Drafting the article or revising it critically for important intellectual content|Final approval of the version to be published	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409347	25909472	JSB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Interpretation of data|Drafting the article or revising it critically for important intellectual content|Final approval of the version to be published	Analyzed the data	Analyzed the data	Formal analysis	YES
4409347	25909472	JSB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Interpretation of data|Drafting the article or revising it critically for important intellectual content|Final approval of the version to be published	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409347	25909472	JSB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Interpretation of data|Drafting the article or revising it critically for important intellectual content|Final approval of the version to be published	Interpretation of data	Analyzed the data	Formal analysis	YES
4409347	25909472	JSB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Interpretation of data|Drafting the article or revising it critically for important intellectual content|Final approval of the version to be published	Drafting the article or revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4409347	25909472	JSB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Interpretation of data|Drafting the article or revising it critically for important intellectual content|Final approval of the version to be published	Final approval of the version to be published	-	-	NO
4409347	25909472	KW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Interpretation of data|Drafting the article or revising it critically for important intellectual content|Final approval of the version to be published	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409347	25909472	KW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Interpretation of data|Drafting the article or revising it critically for important intellectual content|Final approval of the version to be published	Performed the experiments	Performed the experiments	Investigation	YES
4409347	25909472	KW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Interpretation of data|Drafting the article or revising it critically for important intellectual content|Final approval of the version to be published	Analyzed the data	Analyzed the data	Formal analysis	YES
4409347	25909472	KW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Interpretation of data|Drafting the article or revising it critically for important intellectual content|Final approval of the version to be published	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409347	25909472	KW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Interpretation of data|Drafting the article or revising it critically for important intellectual content|Final approval of the version to be published	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409347	25909472	KW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Interpretation of data|Drafting the article or revising it critically for important intellectual content|Final approval of the version to be published	Interpretation of data	Analyzed the data	Formal analysis	YES
4409347	25909472	KW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Interpretation of data|Drafting the article or revising it critically for important intellectual content|Final approval of the version to be published	Drafting the article or revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4409347	25909472	KW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Interpretation of data|Drafting the article or revising it critically for important intellectual content|Final approval of the version to be published	Final approval of the version to be published	-	-	NO
4409347	25909472	MN	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Interpretation of data|Drafting the article or revising it critically for important intellectual content|Final approval of the version to be published	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409347	25909472	MN	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Interpretation of data|Drafting the article or revising it critically for important intellectual content|Final approval of the version to be published	Performed the experiments	Performed the experiments	Investigation	YES
4409347	25909472	MN	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Interpretation of data|Drafting the article or revising it critically for important intellectual content|Final approval of the version to be published	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409347	25909472	MN	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Interpretation of data|Drafting the article or revising it critically for important intellectual content|Final approval of the version to be published	Interpretation of data	Analyzed the data	Formal analysis	YES
4409347	25909472	MN	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Interpretation of data|Drafting the article or revising it critically for important intellectual content|Final approval of the version to be published	Drafting the article or revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4409347	25909472	MN	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Interpretation of data|Drafting the article or revising it critically for important intellectual content|Final approval of the version to be published	Final approval of the version to be published	-	-	NO
4409347	25909472	PMJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Interpretation of data|Drafting the article or revising it critically for important intellectual content|Final approval of the version to be published	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409347	25909472	PMJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Interpretation of data|Drafting the article or revising it critically for important intellectual content|Final approval of the version to be published	Performed the experiments	Performed the experiments	Investigation	YES
4409347	25909472	PMJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Interpretation of data|Drafting the article or revising it critically for important intellectual content|Final approval of the version to be published	Analyzed the data	Analyzed the data	Formal analysis	YES
4409347	25909472	PMJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Interpretation of data|Drafting the article or revising it critically for important intellectual content|Final approval of the version to be published	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409347	25909472	PMJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Interpretation of data|Drafting the article or revising it critically for important intellectual content|Final approval of the version to be published	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409347	25909472	PMJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Interpretation of data|Drafting the article or revising it critically for important intellectual content|Final approval of the version to be published	Interpretation of data	Analyzed the data	Formal analysis	YES
4409347	25909472	PMJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Interpretation of data|Drafting the article or revising it critically for important intellectual content|Final approval of the version to be published	Drafting the article or revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4409347	25909472	PMJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Interpretation of data|Drafting the article or revising it critically for important intellectual content|Final approval of the version to be published	Final approval of the version to be published	-	-	NO
4409347	25909472	RE	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Interpretation of data|Drafting the article or revising it critically for important intellectual content|Final approval of the version to be published	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409347	25909472	RE	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Interpretation of data|Drafting the article or revising it critically for important intellectual content|Final approval of the version to be published	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409347	25909472	RE	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Interpretation of data|Drafting the article or revising it critically for important intellectual content|Final approval of the version to be published	Interpretation of data	Analyzed the data	Formal analysis	YES
4409347	25909472	RE	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Interpretation of data|Drafting the article or revising it critically for important intellectual content|Final approval of the version to be published	Drafting the article or revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4409347	25909472	RE	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Interpretation of data|Drafting the article or revising it critically for important intellectual content|Final approval of the version to be published	Final approval of the version to be published	-	-	NO
4409347	25909472	RM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Interpretation of data|Drafting the article or revising it critically for important intellectual content|Final approval of the version to be published	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409347	25909472	RM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Interpretation of data|Drafting the article or revising it critically for important intellectual content|Final approval of the version to be published	Analyzed the data	Analyzed the data	Formal analysis	YES
4409347	25909472	RM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Interpretation of data|Drafting the article or revising it critically for important intellectual content|Final approval of the version to be published	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409347	25909472	RM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Interpretation of data|Drafting the article or revising it critically for important intellectual content|Final approval of the version to be published	Interpretation of data	Analyzed the data	Formal analysis	YES
4409347	25909472	RM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Interpretation of data|Drafting the article or revising it critically for important intellectual content|Final approval of the version to be published	Drafting the article or revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4409347	25909472	RM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Interpretation of data|Drafting the article or revising it critically for important intellectual content|Final approval of the version to be published	Final approval of the version to be published	-	-	NO
4409347	25909472	TB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Interpretation of data|Drafting the article or revising it critically for important intellectual content|Final approval of the version to be published	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409347	25909472	TB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Interpretation of data|Drafting the article or revising it critically for important intellectual content|Final approval of the version to be published	Performed the experiments	Performed the experiments	Investigation	YES
4409347	25909472	TB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Interpretation of data|Drafting the article or revising it critically for important intellectual content|Final approval of the version to be published	Analyzed the data	Analyzed the data	Formal analysis	YES
4409347	25909472	TB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Interpretation of data|Drafting the article or revising it critically for important intellectual content|Final approval of the version to be published	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409347	25909472	TB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Interpretation of data|Drafting the article or revising it critically for important intellectual content|Final approval of the version to be published	Interpretation of data	Analyzed the data	Formal analysis	YES
4409347	25909472	TB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Interpretation of data|Drafting the article or revising it critically for important intellectual content|Final approval of the version to be published	Drafting the article or revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4409347	25909472	TB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Interpretation of data|Drafting the article or revising it critically for important intellectual content|Final approval of the version to be published	Final approval of the version to be published	-	-	NO
3877947	24369784	HH	2	edited it	edited it	Wrote the paper	Writing - Review & Editing	YES
3877947	24369784	LE	2	edited it|were involved in the final diagnosis and interpretation of bone scans	edited it	Wrote the paper	Writing - Review & Editing	YES
3877947	24369784	LE	2	edited it|were involved in the final diagnosis and interpretation of bone scans	were involved in the final diagnosis and interpretation of bone scans	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3877947	24369784	YN	2	confirmed it	confirmed it	-	-	NO
5632805	29046681	All authors	PLoS52	discussed the results	discussed the results	-	-	NO
5632805	29046681	JH	PLoS52	designed the experiments and performed the data analysis	designed the experiments and performed the data analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5632805	29046681	KP	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5632805	29046681	LS	PLoS52	designed the experiments and performed the data analysis|supervised the study and the concept of the project|wrote the manuscript	designed the experiments and performed the data analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5632805	29046681	LS	PLoS52	designed the experiments and performed the data analysis|supervised the study and the concept of the project|wrote the manuscript	supervised the study and the concept of the project	Conceived and designed the experiments	Conceptualization|Supervision	YES
5632805	29046681	LS	PLoS52	designed the experiments and performed the data analysis|supervised the study and the concept of the project|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5632805	29046681	LU	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5632805	29046681	NDD	PLoS52	designed the experiments and performed the data analysis|supervised the study and the concept of the project|wrote the manuscript	designed the experiments and performed the data analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5632805	29046681	NDD	PLoS52	designed the experiments and performed the data analysis|supervised the study and the concept of the project|wrote the manuscript	supervised the study and the concept of the project	Conceived and designed the experiments	Conceptualization|Supervision	YES
5632805	29046681	NDD	PLoS52	designed the experiments and performed the data analysis|supervised the study and the concept of the project|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5632805	29046681	TF	PLoS52	designed the experiments and performed the data analysis|wrote the manuscript	designed the experiments and performed the data analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5632805	29046681	TF	PLoS52	designed the experiments and performed the data analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5450258	28558786	AS	2	designed and planned the study|made major contributions to data interpretation and writing the manuscript	designed and planned the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5450258	28558786	AS	2	designed and planned the study|made major contributions to data interpretation and writing the manuscript	made major contributions to data interpretation and writing the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
5450258	28558786	CM	2	sequenced the strains and analysed the data	sequenced the strains and analysed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5450258	28558786	DjM	2	sequenced the strains and analysed the data	sequenced the strains and analysed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5450258	28558786	GM	2	designed and planned the study|made major contributions to data interpretation and writing the manuscript	designed and planned the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5450258	28558786	GM	2	designed and planned the study|made major contributions to data interpretation and writing the manuscript	made major contributions to data interpretation and writing the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
5450258	28558786	MD	2	designed and planned the study	designed and planned the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5450258	28558786	MR	2	designed and planned the study	designed and planned the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5450258	28558786	SER	2	made major contributions to data interpretation and writing the manuscript	made major contributions to data interpretation and writing the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
5450258	28558786	SH	2	sequenced the strains and analysed the data	sequenced the strains and analysed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5450258	28558786	SK	2	sequenced the strains and analysed the data	sequenced the strains and analysed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5450258	28558786	VF	2	designed and planned the study|made major contributions to data interpretation and writing the manuscript	designed and planned the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5450258	28558786	VF	2	designed and planned the study|made major contributions to data interpretation and writing the manuscript	made major contributions to data interpretation and writing the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
5855125	29568453	G.A.A.	2	performed the research	performed the research	Performed the experiments	Investigation	YES
5855125	29568453	G.M.	2	performed the research	performed the research	Performed the experiments	Investigation	YES
5855125	29568453	R.A.S.	2	performed the research	performed the research	Performed the experiments	Investigation	YES
5855125	29568453	V.T.K.	2	performed the research	performed the research	Performed the experiments	Investigation	YES
5855125	29568453	X.F.	2	performed the research	performed the research	Performed the experiments	Investigation	YES
5855125	29568453	all authors	2	analyzed and interpreted the results	analyzed and interpreted the results	Analyzed the data	Formal analysis	YES
1779805	17252054	AS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1779805	17252054	AS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1779805	17252054	LS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1779805	17252054	LS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1779805	17252054	RG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1779805	17252054	RG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1779805	17252054	RG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1779805	17252054	RG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1779805	17252054	RG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1779805	17252054	SB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1779805	17252054	SB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1779805	17252054	SB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1779805	17252054	SB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1779805	17252054	VH	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1779805	17252054	VH	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
3877953	24369053	AS	2	drafted the manuscript and contributed to the data collection|drafted the figures and tables and contributed in the collection of data and manuscript editing	drafted the manuscript and contributed to the data collection	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3877953	24369053	AS	2	drafted the manuscript and contributed to the data collection|drafted the figures and tables and contributed in the collection of data and manuscript editing	drafted the figures and tables and contributed in the collection of data and manuscript editing	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Resources|Visualization|Writing - Original Draft|Writing - Review & Editing	YES
3877953	24369053	ASD	2	collected the data and drafted the figures and tables	collected the data and drafted the figures and tables	Performed the experiments|Wrote the paper	Investigation|Visualization|Writing - Original Draft	YES
3877953	24369053	HJB	2	participated in the design and coordination of the study	participated in the design and coordination of the study	Conceived and designed the experiments	Methodology|Project administration	YES
3877953	24369053	JN	2	contributed in the analysis and interpretation of the data and drafting of the manuscript	contributed in the analysis and interpretation of the data and drafting of the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
3877953	24369053	SE	2	conceived of the study concept, interpreted the data, and determined the methodology and directions of manuscript drafting including discussion of results	conceived of the study concept, interpreted the data, and determined the methodology and directions of manuscript drafting including discussion of results	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
3877953	24369053	SG	2	contributed to the concept of the study and critical revision of the article	contributed to the concept of the study and critical revision of the article	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
4409348	25909812	HSK	PLoS5	Conceived and designed the experiments|Recruitment and evaluation of the patients	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409348	25909812	HSK	PLoS5	Conceived and designed the experiments|Recruitment and evaluation of the patients	Recruitment and evaluation of the patients	Performed the experiments	Investigation	YES
4409348	25909812	KY	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Review and critique	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409348	25909812	KY	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Review and critique	Analyzed the data	Analyzed the data	Formal analysis	YES
4409348	25909812	KY	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Review and critique	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409348	25909812	KY	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Review and critique	Review and critique	-	-	NO
4409348	25909812	MJK	PLoS5	Recruitment and evaluation of the patients	Recruitment and evaluation of the patients	Performed the experiments	Investigation	YES
4409348	25909812	OC	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409348	25909812	SJC	PLoS5	Conceived and designed the experiments|Recruitment and evaluation of the patients|Review and critique	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409348	25909812	SJC	PLoS5	Conceived and designed the experiments|Recruitment and evaluation of the patients|Review and critique	Recruitment and evaluation of the patients	Performed the experiments	Investigation	YES
4409348	25909812	SJC	PLoS5	Conceived and designed the experiments|Recruitment and evaluation of the patients|Review and critique	Review and critique	-	-	NO
4409348	25909812	SY	PLoS5	Recruitment and evaluation of the patients	Recruitment and evaluation of the patients	Performed the experiments	Investigation	YES
4409348	25909812	YJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Review and critique	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409348	25909812	YJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Review and critique	Analyzed the data	Analyzed the data	Formal analysis	YES
4409348	25909812	YJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Review and critique	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409348	25909812	YJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Review and critique	Review and critique	-	-	NO
4409348	25909812	YL	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
6053483	30027651	BC	2	critically revised the manuscript for intellectual content	critically revised the manuscript for intellectual content	Wrote the paper	Writing - Review & Editing	YES
6053483	30027651	CL	2	critically revised the manuscript for intellectual content	critically revised the manuscript for intellectual content	Wrote the paper	Writing - Review & Editing	YES
6053483	30027651	DS	2	critically revised the manuscript for intellectual content	critically revised the manuscript for intellectual content	Wrote the paper	Writing - Review & Editing	YES
6053483	30027651	EV	2	conceived the sub-study|drafted the manuscript	conceived the sub-study	Conceived and designed the experiments	Conceptualization	YES
6053483	30027651	EV	2	conceived the sub-study|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
6053483	30027651	FS	2	designed the sub-study protocol|supervised the conducted the interviews under the|drafted the manuscript	designed the sub-study protocol	Conceived and designed the experiments	Methodology	YES
6053483	30027651	FS	2	designed the sub-study protocol|supervised the conducted the interviews under the|drafted the manuscript	supervised the conducted the interviews under the	Performed the experiments	Investigation|Supervision	YES
6053483	30027651	FS	2	designed the sub-study protocol|supervised the conducted the interviews under the|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
6053483	30027651	NM	2	conducted the interviews under the	conducted the interviews under the	Performed the experiments	Investigation	YES
6053483	30027651	NS	2	conducted the interviews under the	conducted the interviews under the	Performed the experiments	Investigation	YES
6053483	30027651	RR	2	conceived the sub-study|drafted the manuscript	conceived the sub-study	Conceived and designed the experiments	Conceptualization	YES
6053483	30027651	RR	2	conceived the sub-study|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
6053483	30027651	SK	2	designed the sub-study protocol|supervised the conducted the interviews under the|critically revised the manuscript for intellectual content	designed the sub-study protocol	Conceived and designed the experiments	Methodology	YES
6053483	30027651	SK	2	designed the sub-study protocol|supervised the conducted the interviews under the|critically revised the manuscript for intellectual content	supervised the conducted the interviews under the	Performed the experiments	Investigation|Supervision	YES
6053483	30027651	SK	2	designed the sub-study protocol|supervised the conducted the interviews under the|critically revised the manuscript for intellectual content	critically revised the manuscript for intellectual content	Wrote the paper	Writing - Review & Editing	YES
5450346	28558656	BS	2	analyzed and interpreted data	analyzed and interpreted data	Analyzed the data	Formal analysis	YES
5450346	28558656	JC	2	wrote the manuscript|contributed tools and materials	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5450346	28558656	JC	2	wrote the manuscript|contributed tools and materials	contributed tools and materials	Contributed reagents/materials/analysis tools	Resources	YES
5450346	28558656	JJ	2	conceived the study|analyzed and interpreted data|wrote the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5450346	28558656	JJ	2	conceived the study|analyzed and interpreted data|wrote the manuscript	analyzed and interpreted data	Analyzed the data	Formal analysis	YES
5450346	28558656	JJ	2	conceived the study|analyzed and interpreted data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5450346	28558656	JO	2	analyzed and interpreted data|contributed tools and materials	analyzed and interpreted data	Analyzed the data	Formal analysis	YES
5450346	28558656	JO	2	analyzed and interpreted data|contributed tools and materials	contributed tools and materials	Contributed reagents/materials/analysis tools	Resources	YES
5450346	28558656	LM	2	conceived the study|wrote the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5450346	28558656	LM	2	conceived the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5450346	28558656	PV	2	wrote the manuscript|contributed tools and materials	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5450346	28558656	PV	2	wrote the manuscript|contributed tools and materials	contributed tools and materials	Contributed reagents/materials/analysis tools	Resources	YES
1779806	17264885	AF	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1779806	17264885	AF	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1779806	17264885	DJ	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1779806	17264885	DJ	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1779806	17264885	DJ	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1779806	17264885	DJ	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1779806	17264885	KM	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1779806	17264885	ML	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1779806	17264885	PH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1779806	17264885	PH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1779806	17264885	PH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1779806	17264885	RA	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1779806	17264885	RB	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1779806	17264885	SD	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1779806	17264885	TC	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5632807	29046680	HB	2	reviewed and finalized the article	reviewed and finalized the article	Wrote the paper	Writing - Review & Editing	YES
5632807	29046680	HL	2	helped in finalizing the contents and structure of the manuscript	helped in finalizing the contents and structure of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5632807	29046680	MA	2	conceived, designed, and mainly developed the article	conceived, designed, and mainly developed the article	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
3878827	24330526	AA	2	analysed the pet data	analysed the pet data	Analyzed the data	Formal analysis	YES
3878827	24330526	AK	2	contributed to conception of the study	contributed to conception of the study	Conceived and designed the experiments	Conceptualization	YES
3878827	24330526	CF	2	synthesised the compounds	synthesised the compounds	Performed the experiments	Investigation	YES
3878827	24330526	ED	2	participated in the biodistribution and blocking studies	participated in the biodistribution and blocking studies	-	-	NO
3878827	24330526	FM	2	wrote the animal ethics protocols and participated in the biodistribution and blocking studies	wrote the animal ethics protocols and participated in the biodistribution and blocking studies	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
3878827	24330526	GR	2	participated in the biodistribution and blocking studies	participated in the biodistribution and blocking studies	-	-	NO
3878827	24330526	IG	2	developed the hplc metabolite studys method	developed the hplc metabolite studys method	Performed the experiments	Investigation|Methodology	YES
3878827	24330526	MG	2	supervised the research group	supervised the research group	-	Supervision	YES
3878827	24330526	NH	2	participated in the biodistribution and blocking studies	participated in the biodistribution and blocking studies	-	-	NO
3878827	24330526	PB	2	participated in the biodistribution and blocking studies	participated in the biodistribution and blocking studies	-	-	NO
3878827	24330526	RS	2	carried out the in vitro and in vivo studies, participated in analysis and interpretation of data, and revised the manuscript	carried out the in vitro and in vivo studies, participated in analysis and interpretation of data, and revised the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
3878827	24330526	TP	2	synthesised and radiosynthesised the compounds, carried out metabolite studies and revised the manuscript	synthesised and radiosynthesised the compounds, carried out metabolite studies and revised the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
3878827	24330526	VN	2	carried out radioreceptor binding studies, analysis and interpretation of data, performed statistical analysis, and drafted the manuscript	carried out radioreceptor binding studies, analysis and interpretation of data, performed statistical analysis, and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4409349	25909751	BKS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409349	25909751	IS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409349	25909751	IS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409349	25909751	IS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409349	25909751	IS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409349	25909751	JMD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409349	25909751	JMD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409349	25909751	JMD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409349	25909751	JMD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409349	25909751	JMD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409349	25909751	KF	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409349	25909751	MZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5452331	28569192	AA	2	made substantial contributions to acquisition of data, to interpretation and modification of the data	made substantial contributions to acquisition of data, to interpretation and modification of the data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5452331	28569192	AI	2	conceived of the study and drafted the manuscript|made substantial contributions to acquisition of data, to interpretation and modification of the data	conceived of the study and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5452331	28569192	AI	2	conceived of the study and drafted the manuscript|made substantial contributions to acquisition of data, to interpretation and modification of the data	made substantial contributions to acquisition of data, to interpretation and modification of the data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5452331	28569192	AP	2	made substantial contributions to acquisition of data, to interpretation and modification of the data	made substantial contributions to acquisition of data, to interpretation and modification of the data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5452331	28569192	All authors	2	involved in drafting the manuscript, read and approved the final version of the manuscript	involved in drafting the manuscript, read and approved the final version of the manuscript	Wrote the paper	Writing - Original Draft	YES
5452331	28569192	IP	2	made substantial contributions to acquisition of data, to interpretation and modification of the data	made substantial contributions to acquisition of data, to interpretation and modification of the data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5452331	28569192	RN	2	conceived of the study and drafted the manuscript|made substantial contributions to acquisition of data, to interpretation and modification of the data	conceived of the study and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5452331	28569192	RN	2	conceived of the study and drafted the manuscript|made substantial contributions to acquisition of data, to interpretation and modification of the data	made substantial contributions to acquisition of data, to interpretation and modification of the data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5452331	28569192	SA	2	conceived of the study and drafted the manuscript|made substantial contributions to acquisition of data, to interpretation and modification of the data	conceived of the study and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5452331	28569192	SA	2	conceived of the study and drafted the manuscript|made substantial contributions to acquisition of data, to interpretation and modification of the data	made substantial contributions to acquisition of data, to interpretation and modification of the data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5452331	28569192	SL	2	made substantial contributions to acquisition of data, to interpretation and modification of the data	made substantial contributions to acquisition of data, to interpretation and modification of the data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
6053484	30027665	All authors	2	reviewed and contributed to the final manuscript	reviewed and contributed to the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6053484	30027665	C.M.	2	facilitated data collection	facilitated data collection	Performed the experiments	Investigation	YES
6053484	30027665	D.B.	2	facilitated data collection	facilitated data collection	Performed the experiments	Investigation	YES
6053484	30027665	D.M.A.	2	provided content expertise	provided content expertise	-	-	NO
6053484	30027665	J.B.	2	facilitated data collection	facilitated data collection	Performed the experiments	Investigation	YES
6053484	30027665	K.C.	2	conceived of the study, coded and analysed the data, and wrote the first draft of the manuscript	conceived of the study, coded and analysed the data, and wrote the first draft of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Data curation|Formal analysis|Writing - Original Draft	YES
6053484	30027665	M.M.	2	facilitated data collection	facilitated data collection	Performed the experiments	Investigation	YES
6053484	30027665	M.N.L.	2	provided content expertise	provided content expertise	-	-	NO
6053484	30027665	M.P.F.	2	facilitated data collection|provided content expertise	facilitated data collection	Performed the experiments	Investigation	YES
6053484	30027665	M.P.F.	2	facilitated data collection|provided content expertise	provided content expertise	-	-	NO
6053484	30027665	S.B.	2	facilitated data collection	facilitated data collection	Performed the experiments	Investigation	YES
6053484	30027665	S.H.V.	2	provided content expertise	provided content expertise	-	-	NO
6053484	30027665	S.N.	2	facilitated data collection	facilitated data collection	Performed the experiments	Investigation	YES
3880002	24382020	JW	2	conducted the fdg pet studies in normal healthy subjects with 18-h fasting before scanning	conducted the fdg pet studies in normal healthy subjects with 18-h fasting before scanning	Performed the experiments	Investigation	YES
3880002	24382020	KI	2	conducted the fdg pet studies in normal subjects and patients with known or suspected cardiac sarcoidosis who had heparin loading plus 12-h fasting before scanning	conducted the fdg pet studies in normal subjects and patients with known or suspected cardiac sarcoidosis who had heparin loading plus 12-h fasting before scanning	Performed the experiments	Investigation	YES
3880002	24382020	KK	2	conducted the fdg pet studies in normal subjects and patients with known or suspected cardiac sarcoidosis who had heparin loading plus 12-h fasting before scanning	conducted the fdg pet studies in normal subjects and patients with known or suspected cardiac sarcoidosis who had heparin loading plus 12-h fasting before scanning	Performed the experiments	Investigation	YES
3880002	24382020	KU	2	conducted the fdg pet studies in normal healthy subjects with 18-h fasting before scanning	conducted the fdg pet studies in normal healthy subjects with 18-h fasting before scanning	Performed the experiments	Investigation	YES
3880002	24382020	MH	2	conceived of the study and participated in its design and coordination	conceived of the study and participated in its design and coordination	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
3880002	24382020	MO	2	conducted the fdg pet studies in normal subjects and patients with known or suspected cardiac sarcoidosis who had heparin loading plus 12-h fasting before scanning	conducted the fdg pet studies in normal subjects and patients with known or suspected cardiac sarcoidosis who had heparin loading plus 12-h fasting before scanning	Performed the experiments	Investigation	YES
3880002	24382020	MaM	2	participated in the design of the study, carried out the image interpretation, performed the statistical analysis, and drafted the manuscript	participated in the design of the study, carried out the image interpretation, performed the statistical analysis, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Visualization|Writing - Original Draft	YES
3880002	24382020	MiM	2	participated in the design of the study, carried out the image interpretation, performed the statistical analysis, and drafted the manuscript	participated in the design of the study, carried out the image interpretation, performed the statistical analysis, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Visualization|Writing - Original Draft	YES
3880002	24382020	OO	2	conducted the fdg pet studies in normal subjects and patients with known or suspected cardiac sarcoidosis who had heparin loading plus 12-h fasting before scanning	conducted the fdg pet studies in normal subjects and patients with known or suspected cardiac sarcoidosis who had heparin loading plus 12-h fasting before scanning	Performed the experiments	Investigation	YES
3880002	24382020	RM	2	conducted the fdg pet studies in normal subjects and patients with known or suspected cardiac sarcoidosis who had heparin loading plus 12-h fasting before scanning	conducted the fdg pet studies in normal subjects and patients with known or suspected cardiac sarcoidosis who had heparin loading plus 12-h fasting before scanning	Performed the experiments	Investigation	YES
3880002	24382020	TN	2	managed the patients data on cardiac status	managed the patients data on cardiac status	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
3880002	24382020	TY	2	managed the patients data about systematic sarcoidosis	managed the patients data about systematic sarcoidosis	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
3880002	24382020	YM	2	conducted the fdg pet studies in normal subjects and patients with known or suspected cardiac sarcoidosis who had heparin loading plus 12-h fasting before scanning	conducted the fdg pet studies in normal subjects and patients with known or suspected cardiac sarcoidosis who had heparin loading plus 12-h fasting before scanning	Performed the experiments	Investigation	YES
3880002	24382020	YY	2	managed the patients data about systematic sarcoidosis	managed the patients data about systematic sarcoidosis	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
1779807	17252055	AB	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1779807	17252055	AB	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1779807	17252055	DM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1779807	17252055	DM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1779807	17252055	DM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1779807	17252055	JF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1779807	17252055	JF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1779807	17252055	JF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1779807	17252055	JR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1779807	17252055	JR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1779807	17252055	JR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1779807	17252055	JR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1779807	17252055	JR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1779807	17252055	KP	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1779807	17252055	KP	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1779807	17252055	KP	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1779807	17252055	MM	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1779807	17252055	MM	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1779807	17252055	MM	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1779807	17252055	MM	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1779807	17252055	MM	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1779807	17252055	MM	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1779807	17252055	MM	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4544874	26345454	Hao Zhou	2	contributed equally as co-first authors of this work	contributed equally as co-first authors of this work	-	-	NO
4544874	26345454	Shun Chen	2	contributed equally as co-first authors of this work	contributed equally as co-first authors of this work	-	-	NO
6053544	30027588	CC	2	conceptualized the main messages|drafted the manuscript	conceptualized the main messages	Conceived and designed the experiments	Conceptualization	YES
6053544	30027588	CC	2	conceptualized the main messages|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
6053544	30027588	JS	2	conceptualized the main messages|provided critical reviews	conceptualized the main messages	Conceived and designed the experiments	Conceptualization	YES
6053544	30027588	JS	2	conceptualized the main messages|provided critical reviews	provided critical reviews	-	-	NO
6053544	30027588	SC	2	conceptualized the main messages|provided critical reviews	conceptualized the main messages	Conceived and designed the experiments	Conceptualization	YES
6053544	30027588	SC	2	conceptualized the main messages|provided critical reviews	provided critical reviews	-	-	NO
3880978	24369858	CF	2	participated in the analysis and interpretation of data and supervised the manuscript	participated in the analysis and interpretation of data and supervised the manuscript	Analyzed the data	Formal analysis|Supervision	YES
3880978	24369858	FH	2	participated in the analysis and interpretation of data and supervised the manuscript	participated in the analysis and interpretation of data and supervised the manuscript	Analyzed the data	Formal analysis|Supervision	YES
3880978	24369858	HA	2	participated in the analysis and interpretation of data and supervised the manuscript	participated in the analysis and interpretation of data and supervised the manuscript	Analyzed the data	Formal analysis|Supervision	YES
3880978	24369858	IS	2	participated in the design of the study and in the analysis and interpretation of data and drafted the manuscript	participated in the design of the study and in the analysis and interpretation of data and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3880978	24369858	JMMR	2	participated in the analysis and interpretation of data and supervised the manuscript	participated in the analysis and interpretation of data and supervised the manuscript	Analyzed the data	Formal analysis|Supervision	YES
3880978	24369858	JR	2	participated in the design of the study and in the analysis and interpretation of data and drafted the manuscript	participated in the design of the study and in the analysis and interpretation of data and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5632816	29046690	BL	PLoS52	performed research|analyzed data	performed research	Performed the experiments	Investigation	YES
5632816	29046690	BL	PLoS52	performed research|analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5632816	29046690	DQ	PLoS52	performed research|analyzed data|wrote the paper	performed research	Performed the experiments	Investigation	YES
5632816	29046690	DQ	PLoS52	performed research|analyzed data|wrote the paper	analyzed data	Analyzed the data	Formal analysis	YES
5632816	29046690	DQ	PLoS52	performed research|analyzed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5632816	29046690	DW	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
5632816	29046690	JM	PLoS52	performed research|analyzed data	performed research	Performed the experiments	Investigation	YES
5632816	29046690	JM	PLoS52	performed research|analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5632816	29046690	WH	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
5632816	29046690	XW	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
5632816	29046690	YN	PLoS52	designed research|performed research|analyzed data|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
5632816	29046690	YN	PLoS52	designed research|performed research|analyzed data|wrote the paper	performed research	Performed the experiments	Investigation	YES
5632816	29046690	YN	PLoS52	designed research|performed research|analyzed data|wrote the paper	analyzed data	Analyzed the data	Formal analysis	YES
5632816	29046690	YN	PLoS52	designed research|performed research|analyzed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5632816	29046690	YX	PLoS52	designed research|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
5632816	29046690	YX	PLoS52	designed research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5452409	28569133	AKC	2	contributed to the final manuscript	contributed to the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5452409	28569133	ARLC	2	completed all experiments, analysed and interpreted data, and drafted the manuscript	completed all experiments, analysed and interpreted data, and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5452409	28569133	ASW	2	contributed to the final manuscript	contributed to the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5452409	28569133	CR	2	contributed to the final manuscript	contributed to the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5452409	28569133	GN	2	implemented the bioinformatics tools and assisted with their use	implemented the bioinformatics tools and assisted with their use	Performed the experiments	Formal analysis|Investigation	YES
5452409	28569133	JAL	2	contributed to the final manuscript	contributed to the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5452409	28569133	MB	2	implemented the bioinformatics tools and assisted with their use	implemented the bioinformatics tools and assisted with their use	Performed the experiments	Formal analysis|Investigation	YES
5452409	28569133	OPF	2	contributed to the initial method design, including sequencing and oversaw library preparation	contributed to the initial method design, including sequencing and oversaw library preparation	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources|Supervision	YES
5452409	28569133	TraDIS	2	the optimisation of sequencing strategies	the optimisation of sequencing strategies	Performed the experiments	Investigation	YES
4409351	25909894	DJS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409351	25909894	DJS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409351	25909894	DJS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409351	25909894	DJS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1779808	17264881	AA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1779808	17264881	AA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1779808	17264881	AA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1779808	17264881	HE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1779808	17264881	HE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1779808	17264881	HE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1779808	17264881	HE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1779808	17264881	HE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1779808	17264881	KA	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1779808	17264881	KA	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1779808	17264881	KF	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1779808	17264881	KF	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5633601	29051768	All authors	2	listed have made a substantial, direct and intellectual contribution to the work, and approved it for publication	listed have made a substantial, direct and intellectual contribution to the work, and approved it for publication	-	-	NO
6055043	30033563	AC	2	edited the manuscript|contributed to the stigma index revisions and interpreted results	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
6055043	30033563	AC	2	edited the manuscript|contributed to the stigma index revisions and interpreted results	contributed to the stigma index revisions and interpreted results	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
6055043	30033563	AG	2	conceptualized key messages|contributed to the stigma index revisions and interpreted results	conceptualized key messages	Conceived and designed the experiments	Conceptualization	YES
6055043	30033563	AG	2	conceptualized key messages|contributed to the stigma index revisions and interpreted results	contributed to the stigma index revisions and interpreted results	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
6055043	30033563	AJ	2	contributed to the stigma index revisions and interpreted results	contributed to the stigma index revisions and interpreted results	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
6055043	30033563	BF	2	drafted the manuscript|conceptualized key messages|contributed to the stigma index revisions and interpreted results	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
6055043	30033563	BF	2	drafted the manuscript|conceptualized key messages|contributed to the stigma index revisions and interpreted results	conceptualized key messages	Conceived and designed the experiments	Conceptualization	YES
6055043	30033563	BF	2	drafted the manuscript|conceptualized key messages|contributed to the stigma index revisions and interpreted results	contributed to the stigma index revisions and interpreted results	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
6055043	30033563	CM	2	edited the manuscript|contributed to the stigma index revisions and interpreted results	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
6055043	30033563	CM	2	edited the manuscript|contributed to the stigma index revisions and interpreted results	contributed to the stigma index revisions and interpreted results	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
6055043	30033563	FA	2	contributed to the stigma index revisions and interpreted results	contributed to the stigma index revisions and interpreted results	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
6055043	30033563	JP	2	conceptualized key messages|edited the manuscript|contributed to the stigma index revisions and interpreted results	conceptualized key messages	Conceived and designed the experiments	Conceptualization	YES
6055043	30033563	JP	2	conceptualized key messages|edited the manuscript|contributed to the stigma index revisions and interpreted results	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
6055043	30033563	JP	2	conceptualized key messages|edited the manuscript|contributed to the stigma index revisions and interpreted results	contributed to the stigma index revisions and interpreted results	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
6055043	30033563	LN	2	conceptualized key messages|edited the manuscript|contributed to the stigma index revisions and interpreted results	conceptualized key messages	Conceived and designed the experiments	Conceptualization	YES
6055043	30033563	LN	2	conceptualized key messages|edited the manuscript|contributed to the stigma index revisions and interpreted results	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
6055043	30033563	LN	2	conceptualized key messages|edited the manuscript|contributed to the stigma index revisions and interpreted results	contributed to the stigma index revisions and interpreted results	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
6055043	30033563	LS	2	edited the manuscript|contributed to the stigma index revisions and interpreted results	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
6055043	30033563	LS	2	edited the manuscript|contributed to the stigma index revisions and interpreted results	contributed to the stigma index revisions and interpreted results	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
6055043	30033563	SB	2	conceptualized key messages|edited the manuscript|contributed to the stigma index revisions and interpreted results	conceptualized key messages	Conceived and designed the experiments	Conceptualization	YES
6055043	30033563	SB	2	conceptualized key messages|edited the manuscript|contributed to the stigma index revisions and interpreted results	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
6055043	30033563	SB	2	conceptualized key messages|edited the manuscript|contributed to the stigma index revisions and interpreted results	contributed to the stigma index revisions and interpreted results	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
6055043	30033563	SG	2	edited the manuscript|contributed to the stigma index revisions and interpreted results	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
6055043	30033563	SG	2	edited the manuscript|contributed to the stigma index revisions and interpreted results	contributed to the stigma index revisions and interpreted results	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
6055043	30033563	UA	2	edited the manuscript|contributed to the stigma index revisions and interpreted results	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
6055043	30033563	UA	2	edited the manuscript|contributed to the stigma index revisions and interpreted results	contributed to the stigma index revisions and interpreted results	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4409352	25909657	GJH	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409352	25909657	NH	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409352	25909657	NT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409352	25909657	NT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409352	25909657	NT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409352	25909657	NT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409352	25909657	NT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409352	25909657	WD	PLoS5	Helped draft and revise the manuscript	Helped draft and revise the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4409352	25909657	ZGL	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
3882100	24387284	AHS	2	designed and performed experiments, collected the data, performed statistical analysis and wrote the paper	designed and performed experiments, collected the data, performed statistical analysis and wrote the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
3882100	24387284	CKF	2	were involved with in vivo experiments and data collection	were involved with in vivo experiments and data collection	Performed the experiments	Investigation	YES
3882100	24387284	FA	2	designed and performed experiments, collected the data and performed statistical analysis	designed and performed experiments, collected the data and performed statistical analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
3882100	24387284	JM	2	developed and performed immunohistochemistry and imaging of the tissue microarray	developed and performed immunohistochemistry and imaging of the tissue microarray	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
3882100	24387284	JMD	2	were involved with in vivo experiments and data collection	were involved with in vivo experiments and data collection	Performed the experiments	Investigation	YES
3882100	24387284	MPB	2	participated in the design of the study, data collection, analysis and interpretation, and in writing the manuscript	participated in the design of the study, data collection, analysis and interpretation, and in writing the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
3882100	24387284	NSCLC	2	patients with la expression and performed statistical analysis	patients with la expression and performed statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5633614	29051769	AZ	2	constructed all the vectors	constructed all the vectors	Performed the experiments	Investigation	YES
5633614	29051769	DC	2	performed genetic transformations	performed genetic transformations	Performed the experiments	Investigation	YES
5633614	29051769	FG	2	performed the expression analysis and tissue localization and cell localization	performed the expression analysis and tissue localization and cell localization	Performed the experiments	Investigation	YES
5633614	29051769	GY	2	performed the phenotypic characterization of the mutant and transgenic plants	performed the phenotypic characterization of the mutant and transgenic plants	Performed the experiments	Investigation	YES
5633614	29051769	HL	2	carried out the field experiments and investigations	carried out the field experiments and investigations	Performed the experiments	Investigation	YES
5633614	29051769	JiZ	2	performed the cloning and functional analysis and collected almost all of the data	performed the cloning and functional analysis and collected almost all of the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5633614	29051769	JuZ	2	constructed all the vectors	constructed all the vectors	Performed the experiments	Investigation	YES
5633614	29051769	LW	2	carried out the field experiments and investigations	carried out the field experiments and investigations	Performed the experiments	Investigation	YES
5633614	29051769	PL	2	designed the experiments and directed the project	designed the experiments and directed the project	Conceived and designed the experiments	Methodology|Supervision	YES
5633614	29051769	QD	2	carried out the field experiments and investigations	carried out the field experiments and investigations	Performed the experiments	Investigation	YES
5633614	29051769	SL	2	designed the experiments and directed the project|analyzed the data and wrote the paper	designed the experiments and directed the project	Conceived and designed the experiments	Methodology|Supervision	YES
5633614	29051769	SL	2	designed the experiments and directed the project|analyzed the data and wrote the paper	analyzed the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5633614	29051769	SW	2	carried out the field experiments and investigations	carried out the field experiments and investigations	Performed the experiments	Investigation	YES
5633614	29051769	TL	2	performed the phenotypic characterization of the mutant and transgenic plants	performed the phenotypic characterization of the mutant and transgenic plants	Performed the experiments	Investigation	YES
5633614	29051769	WL	2	performed genetic transformations	performed genetic transformations	Performed the experiments	Investigation	YES
5633614	29051769	XW	2	performed the phenotypic characterization of the mutant and transgenic plants	performed the phenotypic characterization of the mutant and transgenic plants	Performed the experiments	Investigation	YES
5633614	29051769	YC	2	performed genetic transformations	performed genetic transformations	Performed the experiments	Investigation	YES
5633614	29051769	YL	2	constructed all the vectors	constructed all the vectors	Performed the experiments	Investigation	YES
5633614	29051769	YR	2	performed the expression analysis and tissue localization and cell localization	performed the expression analysis and tissue localization and cell localization	Performed the experiments	Investigation	YES
5633614	29051769	ZH	2	performed the cloning and functional analysis and collected almost all of the data	performed the cloning and functional analysis and collected almost all of the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6055118	30033536	AG	2	are co- investigators who assisted with the overall design of the study and offered feedback to the draft manuscript	are co- investigators who assisted with the overall design of the study and offered feedback to the draft manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
6055118	30033536	GA	2	is the principal investigator of the blue-ribbon boys study and was the lead writer	is the principal investigator of the blue-ribbon boys study and was the lead writer	Conceived and designed the experiments|Wrote the paper	Conceptualization|Funding acquisition	YES
6055118	30033536	GMS	2	is a co-principal investigator, led all data analysis and co-wrote the methods and results reported here	is a co-principal investigator, led all data analysis and co-wrote the methods and results reported here	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Funding acquisition|Writing - Original Draft	YES
6055118	30033536	KM	2	are co- investigators who assisted with the overall design of the study and offered feedback to the draft manuscript	are co- investigators who assisted with the overall design of the study and offered feedback to the draft manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
6055118	30033536	SA	2	are co- investigators who assisted with the overall design of the study and offered feedback to the draft manuscript	are co- investigators who assisted with the overall design of the study and offered feedback to the draft manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
6055118	30033536	SH	2	are co- investigators who assisted with the overall design of the study and offered feedback to the draft manuscript	are co- investigators who assisted with the overall design of the study and offered feedback to the draft manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
1779809	17264882	BG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Group leader under whose supervision the work was designed and performed	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1779809	17264882	BG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Group leader under whose supervision the work was designed and performed	Analyzed the data	Analyzed the data	Formal analysis	YES
1779809	17264882	BG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Group leader under whose supervision the work was designed and performed	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1779809	17264882	BG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Group leader under whose supervision the work was designed and performed	Group leader under whose supervision the work was designed and performed	Conceived and designed the experiments|Performed the experiments	Investigation|Supervision	YES
1779809	17264882	CL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1779809	17264882	CL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1779809	17264882	CL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1779809	17264882	CL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1779809	17264882	DG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1779809	17264882	DG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1779809	17264882	DG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1779809	17264882	DH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Group leader under whose supervision the work was designed and performed	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1779809	17264882	DH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Group leader under whose supervision the work was designed and performed	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1779809	17264882	DH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Group leader under whose supervision the work was designed and performed	Group leader under whose supervision the work was designed and performed	Conceived and designed the experiments|Performed the experiments	Investigation|Supervision	YES
1779809	17264882	EK	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1779809	17264882	KA	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1779809	17264882	LA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Group leader under whose supervision the work was designed and performed	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1779809	17264882	LA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Group leader under whose supervision the work was designed and performed	Analyzed the data	Analyzed the data	Formal analysis	YES
1779809	17264882	LA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Group leader under whose supervision the work was designed and performed	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1779809	17264882	LA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Group leader under whose supervision the work was designed and performed	Group leader under whose supervision the work was designed and performed	Conceived and designed the experiments|Performed the experiments	Investigation|Supervision	YES
3892075	24360192	CS	2	performed and analyzed ct angiography	performed and analyzed ct angiography	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3892075	24360192	CT	2	data and drafted the manuscript	data and drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
3892075	24360192	LS	2	performed pulmonary vein isolation|conceived of the study|participated in the design of the study and drafted the manuscript	performed pulmonary vein isolation	Performed the experiments	Investigation	YES
3892075	24360192	LS	2	performed pulmonary vein isolation|conceived of the study|participated in the design of the study and drafted the manuscript	conceived of the study	Conceived and designed the experiments	Conceptualization	YES
3892075	24360192	LS	2	performed pulmonary vein isolation|conceived of the study|participated in the design of the study and drafted the manuscript	participated in the design of the study and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3892075	24360192	MS	2	conceived of the study|participated in the design of the study and drafted the manuscript	conceived of the study	Conceived and designed the experiments	Conceptualization	YES
3892075	24360192	MS	2	conceived of the study|participated in the design of the study and drafted the manuscript	participated in the design of the study and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3892075	24360192	OS	2	participated in the design of the study and drafted the manuscript	participated in the design of the study and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3892075	24360192	PL	2	carried out the patients follow-up	carried out the patients follow-up	Performed the experiments	Investigation	YES
5452627	28569138	All authors	PLoS52	reviewed and approved the manuscript	reviewed and approved the manuscript	Wrote the paper	Writing - Review & Editing	YES
5452627	28569138	GYL	PLoS52	performed sscp and hrm experiments	performed sscp and hrm experiments	Performed the experiments	Investigation	YES
5452627	28569138	HHZ	PLoS52	cultivated the cotton plants in the field and collected the fiber and ovule samples	cultivated the cotton plants in the field and collected the fiber and ovule samples	Performed the experiments	Investigation	YES
5452627	28569138	JFZ	PLoS52	conceived and designed the experiments|revised the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5452627	28569138	JFZ	PLoS52	conceived and designed the experiments|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5452627	28569138	JWY	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5452627	28569138	MW	PLoS52	performed qrt-pcr experiments	performed qrt-pcr experiments	Performed the experiments	Investigation	YES
5452627	28569138	SXY	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5452627	28569138	WFP	PLoS52	cultivated the cotton plants in the field and collected the fiber and ovule samples	cultivated the cotton plants in the field and collected the fiber and ovule samples	Performed the experiments	Investigation	YES
5452627	28569138	XHL	PLoS52	performed the data analysis and wrote the manuscript	performed the data analysis and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4409353	25909484	AH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409353	25909484	AH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409353	25909484	AH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409353	25909484	BV	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409353	25909484	BV	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409353	25909484	CM	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409353	25909484	GS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409353	25909484	JA	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409353	25909484	JA	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409353	25909484	JA	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409353	25909484	KE	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409353	25909484	MD	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409353	25909484	MT	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409353	25909484	TW	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5633857	29051765	BY	PLoS52	contributed reagents/materials/analysis tools	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5633857	29051765	CM	PLoS52	contributed reagents/materials/analysis tools	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5633857	29051765	JS	PLoS52	contributed reagents/materials/analysis tools	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5633857	29051765	JT	PLoS52	conceived and designed the experiments|reviewed the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5633857	29051765	JT	PLoS52	conceived and designed the experiments|reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5633857	29051765	JW	PLoS52	contributed reagents/materials/analysis tools	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5633857	29051765	LC	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5633857	29051765	MH	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data and wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5633857	29051765	MH	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data and wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5633857	29051765	MH	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5633857	29051765	TF	PLoS52	contributed reagents/materials/analysis tools	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5633857	29051765	TT	PLoS52	performed the qpcr assays	performed the qpcr assays	Performed the experiments	Investigation	YES
5633857	29051765	XL	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5633857	29051765	YZ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
3895783	24397937	AB	PLoS52	wrote the paper|designed the research|analyzed the scans	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3895783	24397937	AB	PLoS52	wrote the paper|designed the research|analyzed the scans	designed the research	Conceived and designed the experiments	Methodology	YES
3895783	24397937	AB	PLoS52	wrote the paper|designed the research|analyzed the scans	analyzed the scans	Analyzed the data	Formal analysis	YES
3895783	24397937	JV	PLoS52	wrote the paper|designed the research	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3895783	24397937	JV	PLoS52	wrote the paper|designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
3895783	24397937	JZ	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3895783	24397937	KH	PLoS52	wrote the paper|provided patient data	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3895783	24397937	KH	PLoS52	wrote the paper|provided patient data	provided patient data	Contributed reagents/materials/analysis tools	Resources	YES
3895783	24397937	LM	PLoS52	performed the research	performed the research	Performed the experiments	Investigation	YES
3895783	24397937	MJ	PLoS52	wrote the paper|designed the research|analyzed and interpreted the data	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3895783	24397937	MJ	PLoS52	wrote the paper|designed the research|analyzed and interpreted the data	designed the research	Conceived and designed the experiments	Methodology	YES
3895783	24397937	MJ	PLoS52	wrote the paper|designed the research|analyzed and interpreted the data	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
3895783	24397937	MW	PLoS52	wrote the paper|designed the research|analyzed and interpreted the data	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3895783	24397937	MW	PLoS52	wrote the paper|designed the research|analyzed and interpreted the data	designed the research	Conceived and designed the experiments	Methodology	YES
3895783	24397937	MW	PLoS52	wrote the paper|designed the research|analyzed and interpreted the data	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
3895783	24397937	NH	PLoS52	analyzed the scans	analyzed the scans	Analyzed the data	Formal analysis	YES
3895783	24397937	OH	PLoS52	wrote the paper|analyzed the scans	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3895783	24397937	OH	PLoS52	wrote the paper|analyzed the scans	analyzed the scans	Analyzed the data	Formal analysis	YES
3895783	24397937	SC	PLoS52	wrote the paper|provided patient data|performed the research	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3895783	24397937	SC	PLoS52	wrote the paper|provided patient data|performed the research	provided patient data	Contributed reagents/materials/analysis tools	Resources	YES
3895783	24397937	SC	PLoS52	wrote the paper|provided patient data|performed the research	performed the research	Performed the experiments	Investigation	YES
3895783	24397937	SS	PLoS52	wrote the paper|performed the research	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3895783	24397937	SS	PLoS52	wrote the paper|performed the research	performed the research	Performed the experiments	Investigation	YES
6055119	30033644	All authors	PLoS52	critically reviewed and approved the manuscript	critically reviewed and approved the manuscript	Wrote the paper	Writing - Review & Editing	YES
6055119	30033644	CN	PLoS52	coordinated the study	coordinated the study	-	Project administration	YES
6055119	30033644	DM	PLoS52	implemented the study at their sites	implemented the study at their sites	Performed the experiments	Investigation	YES
6055119	30033644	DT	PLoS52	designed the analysis|analysed the data	designed the analysis	Conceived and designed the experiments	-	YES
6055119	30033644	DT	PLoS52	designed the analysis|analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
6055119	30033644	JB	PLoS52	supervised laboratory procedures	supervised laboratory procedures	Performed the experiments	Investigation|Supervision	YES
6055119	30033644	JJ	PLoS52	coordinated the study	coordinated the study	-	Project administration	YES
6055119	30033644	KH	PLoS52	coordinated the study	coordinated the study	-	Project administration	YES
6055119	30033644	NP	PLoS52	designed the study|led the study and wrote the first draft of the report|edited and finalized the manuscript for submission|designed the analysis	designed the study	Conceived and designed the experiments	Methodology	YES
6055119	30033644	NP	PLoS52	designed the study|led the study and wrote the first draft of the report|edited and finalized the manuscript for submission|designed the analysis	led the study and wrote the first draft of the report	Wrote the paper	Writing - Original Draft	YES
6055119	30033644	NP	PLoS52	designed the study|led the study and wrote the first draft of the report|edited and finalized the manuscript for submission|designed the analysis	edited and finalized the manuscript for submission	Wrote the paper	Writing - Review & Editing	YES
6055119	30033644	NP	PLoS52	designed the study|led the study and wrote the first draft of the report|edited and finalized the manuscript for submission|designed the analysis	designed the analysis	Conceived and designed the experiments	-	YES
6055119	30033644	NU	PLoS52	implemented the study at their sites	implemented the study at their sites	Performed the experiments	Investigation	YES
6055119	30033644	PM	PLoS52	oversaw data management	oversaw data management	Analyzed the data	Data curation|Supervision	YES
6055119	30033644	PP	PLoS52	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
6055119	30033644	PeP	PLoS52	implemented the study at their sites	implemented the study at their sites	Performed the experiments	Investigation	YES
6055119	30033644	SH	PLoS52	implemented the study at their sites	implemented the study at their sites	Performed the experiments	Investigation	YES
6055119	30033644	SP	PLoS52	implemented the study at their sites	implemented the study at their sites	Performed the experiments	Investigation	YES
6055119	30033644	SS	PLoS52	implemented the study at their sites	implemented the study at their sites	Performed the experiments	Investigation	YES
6055119	30033644	ST	PLoS52	implemented the study at their sites	implemented the study at their sites	Performed the experiments	Investigation	YES
6055119	30033644	TA	PLoS52	designed the study|edited and finalized the manuscript for submission	designed the study	Conceived and designed the experiments	Methodology	YES
6055119	30033644	TA	PLoS52	designed the study|edited and finalized the manuscript for submission	edited and finalized the manuscript for submission	Wrote the paper	Writing - Review & Editing	YES
6055119	30033644	TP	PLoS52	supervised laboratory procedures	supervised laboratory procedures	Performed the experiments	Investigation|Supervision	YES
6055119	30033644	TS	PLoS52	coordinated the study	coordinated the study	-	Project administration	YES
5455115	28571573	AE	2	revised the manuscript and jointly supervised the work	revised the manuscript and jointly supervised the work	Wrote the paper	Supervision|Writing - Review & Editing	YES
5455115	28571573	DP	2	was involved in the collection of the isolates, contributed to latex agglutination and dna extraction for the isolates in this study and contributed to the interpretation of the data and writing of the manuscript	was involved in the collection of the isolates, contributed to latex agglutination and dna extraction for the isolates in this study and contributed to the interpretation of the data and writing of the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft	YES
5455115	28571573	GK	2	performed the bioinformatics analysis, contributed to the interpretation of the data and drafted the manuscript	performed the bioinformatics analysis, contributed to the interpretation of the data and drafted the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft	YES
5455115	28571573	VJC	2	revised the manuscript and jointly supervised the work	revised the manuscript and jointly supervised the work	Wrote the paper	Supervision|Writing - Review & Editing	YES
3900669	24428856	AC	2	performed all radiological interpretations	performed all radiological interpretations	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3900669	24428856	AW	2	assisted with data collection and organization	assisted with data collection and organization	Performed the experiments	Investigation	YES
3900669	24428856	CH	2	were responsible for study concept and design	were responsible for study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
3900669	24428856	DR	2	were responsible for study concept and design	were responsible for study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
3900669	24428856	KJ	2	performed all radiological interpretations	performed all radiological interpretations	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3900669	24428856	MO	2	were responsible for study concept and design	were responsible for study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
3900669	24428856	RC	2	assisted in study design and performed and validated all statistical analyses	assisted in study design and performed and validated all statistical analyses	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology|Validation	YES
3900669	24428856	RL	2	assisted in study design and performed and validated all statistical analyses	assisted in study design and performed and validated all statistical analyses	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology|Validation	YES
4409354	25909602	CK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409354	25909602	CK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409354	25909602	CY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409354	25909602	CY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409354	25909602	CY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409354	25909602	CY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409354	25909602	CY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409354	25909602	MJ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409354	25909602	MJ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409354	25909602	MJ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409354	25909602	ST	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409354	25909602	ST	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409354	25909602	ST	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409354	25909602	ST	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5633859	29051767	AA	7	Performed experiments|Analyzed the data and wrote the manuscript	Performed experiments	Performed the experiments	Investigation	YES
5633859	29051767	AA	7	Performed experiments|Analyzed the data and wrote the manuscript	Analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5633859	29051767	AF	7	Planned and designed the research|Performed experiments|Analyzed the data and wrote the manuscript	Planned and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5633859	29051767	AF	7	Planned and designed the research|Performed experiments|Analyzed the data and wrote the manuscript	Performed experiments	Performed the experiments	Investigation	YES
5633859	29051767	AF	7	Planned and designed the research|Performed experiments|Analyzed the data and wrote the manuscript	Analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5633859	29051767	DP	7	Planned and designed the research|Performed experiments|Analyzed the data and wrote the manuscript	Planned and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5633859	29051767	DP	7	Planned and designed the research|Performed experiments|Analyzed the data and wrote the manuscript	Performed experiments	Performed the experiments	Investigation	YES
5633859	29051767	DP	7	Planned and designed the research|Performed experiments|Analyzed the data and wrote the manuscript	Analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5633859	29051767	NB	7	Planned and designed the research|Analyzed the data and wrote the manuscript	Planned and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5633859	29051767	NB	7	Planned and designed the research|Analyzed the data and wrote the manuscript	Analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5633859	29051767	RG	7	Performed experiments	Performed experiments	Performed the experiments	Investigation	YES
1781339	17285146	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1781339	17285146	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1781339	17285146	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1781339	17285146	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1781339	17285146	DH	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1781339	17285146	DH	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1781339	17285146	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1781339	17285146	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1781339	17285146	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1781339	17285146	NC	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1781339	17285146	NC	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3901766	24450990	BS	4	The statistical analysis was performed by|Manuscript editing was done by	The statistical analysis was performed by	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3901766	24450990	BS	4	The statistical analysis was performed by|Manuscript editing was done by	Manuscript editing was done by	Wrote the paper	Writing - Review & Editing	YES
3901766	24450990	CP	4	The clinical studies were conducted by|Manuscript editing was done by	The clinical studies were conducted by	Performed the experiments	Investigation	YES
3901766	24450990	CP	4	The clinical studies were conducted by|Manuscript editing was done by	Manuscript editing was done by	Wrote the paper	Writing - Review & Editing	YES
3901766	24450990	JD	4	Manuscript editing was done by	Manuscript editing was done by	Wrote the paper	Writing - Review & Editing	YES
3901766	24450990	KS	4	Manuscript editing was done by	Manuscript editing was done by	Wrote the paper	Writing - Review & Editing	YES
3901766	24450990	MWH	4	Literature research was done by|The clinical studies were conducted by|Manuscript editing was done by	Literature research was done by	-	Formal analysis	YES
3901766	24450990	MWH	4	Literature research was done by|The clinical studies were conducted by|Manuscript editing was done by	The clinical studies were conducted by	Performed the experiments	Investigation	YES
3901766	24450990	MWH	4	Literature research was done by|The clinical studies were conducted by|Manuscript editing was done by	Manuscript editing was done by	Wrote the paper	Writing - Review & Editing	YES
3901766	24450990	PG	4	The clinical studies were conducted by	The clinical studies were conducted by	Performed the experiments	Investigation	YES
3901766	24450990	PVH	4	Literature research was done by|The clinical studies were conducted by|Manuscript editing was done by	Literature research was done by	-	Formal analysis	YES
3901766	24450990	PVH	4	Literature research was done by|The clinical studies were conducted by|Manuscript editing was done by	The clinical studies were conducted by	Performed the experiments	Investigation	YES
3901766	24450990	PVH	4	Literature research was done by|The clinical studies were conducted by|Manuscript editing was done by	Manuscript editing was done by	Wrote the paper	Writing - Review & Editing	YES
3901766	24450990	RW	4	Manuscript editing was done by	Manuscript editing was done by	Wrote the paper	Writing - Review & Editing	YES
3901766	24450990	TDC	4	Literature research was done by|The clinical studies were conducted by|Manuscript editing was done by	Literature research was done by	-	Formal analysis	YES
3901766	24450990	TDC	4	Literature research was done by|The clinical studies were conducted by|Manuscript editing was done by	The clinical studies were conducted by	Performed the experiments	Investigation	YES
3901766	24450990	TDC	4	Literature research was done by|The clinical studies were conducted by|Manuscript editing was done by	Manuscript editing was done by	Wrote the paper	Writing - Review & Editing	YES
3901766	24450990	all authors	4	and manuscript final version approval were done by	and manuscript final version approval were done by	-	-	NO
6055120	30033684	DG	2	contributed to the data analysis, outlining of the manuscript, and technical editing	contributed to the data analysis, outlining of the manuscript, and technical editing	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
6055120	30033684	KL	2	contributed to analysis design, manuscript writing and editing	contributed to analysis design, manuscript writing and editing	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6055120	30033684	MK	2	cleaned the dataset and contributed to the analysis and manuscript writing	cleaned the dataset and contributed to the analysis and manuscript writing	Analyzed the data|Wrote the paper	Data curation|Formal analysis|Writing - Original Draft	YES
6055120	30033684	OS	2	provided technical inputs	provided technical inputs	-	-	NO
5455116	28576139	DC	2	designed the analysis and wrote the manuscript	designed the analysis and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
5455116	28576139	KKS	2	performed the analysis	performed the analysis	Performed the experiments	Investigation	YES
4409355	25909331	AAH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409355	25909331	AAH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4409355	25909331	AAH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409355	25909331	AH	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409355	25909331	JMP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409355	25909331	JMP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4409355	25909331	JMP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409355	25909331	KB	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409355	25909331	KL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409355	25909331	KL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409355	25909331	KL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409355	25909331	KL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409355	25909331	PG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409355	25909331	SR	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409355	25909331	SR	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409355	25909331	TT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409355	25909331	TT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409355	25909331	TT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409355	25909331	TT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3904930	24451009	AB	2	conceived of the study and participated in its design and coordination	conceived of the study and participated in its design and coordination	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
3904930	24451009	CB	2	conceived of the study and participated in its design and coordination	conceived of the study and participated in its design and coordination	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
3904930	24451009	CMS	2	carried out the data acquisition	carried out the data acquisition	Performed the experiments	Investigation	YES
3904930	24451009	FPK	2	performed the image processing and analysis and drafted the manuscript	performed the image processing and analysis and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Investigation|Visualization|Writing - Original Draft	YES
3904930	24451009	GIW	2	performed the image processing and analysis and drafted the manuscript	performed the image processing and analysis and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Investigation|Visualization|Writing - Original Draft	YES
3904930	24451009	KL	2	carried out the data acquisition	carried out the data acquisition	Performed the experiments	Investigation	YES
1781341	17285142	XX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1781341	17285142	XX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1781341	17285142	XX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1781341	17285142	XX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1781341	17285142	XX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6055121	30033535	All authors	2	have reviewed and approved the final manuscript	have reviewed and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6055121	30033535	BEO	2	were involved in reviewing and finalizing the manuscript	were involved in reviewing and finalizing the manuscript	Wrote the paper	Writing - Review & Editing	YES
6055121	30033535	GJM	2	were involved equally in the development of this manuscript	were involved equally in the development of this manuscript	Wrote the paper	Writing - Original Draft	YES
6055121	30033535	HKM	2	designed and implemented the intervention|were involved in reviewing and finalizing the manuscript	designed and implemented the intervention	Conceived and designed the experiments|Performed the experiments	Investigation	YES
6055121	30033535	HKM	2	designed and implemented the intervention|were involved in reviewing and finalizing the manuscript	were involved in reviewing and finalizing the manuscript	Wrote the paper	Writing - Review & Editing	YES
6055121	30033535	JMM	2	designed and implemented the intervention	designed and implemented the intervention	Conceived and designed the experiments|Performed the experiments	Investigation	YES
6055121	30033535	PB	2	were involved equally in the development of this manuscript|designed and implemented the intervention|were involved in analysing the quantitative data	were involved equally in the development of this manuscript	Wrote the paper	Writing - Original Draft	YES
6055121	30033535	PB	2	were involved equally in the development of this manuscript|designed and implemented the intervention|were involved in analysing the quantitative data	designed and implemented the intervention	Conceived and designed the experiments|Performed the experiments	Investigation	YES
6055121	30033535	PB	2	were involved equally in the development of this manuscript|designed and implemented the intervention|were involved in analysing the quantitative data	were involved in analysing the quantitative data	Analyzed the data	Formal analysis	YES
6055121	30033535	RLD	2	were involved in reviewing and finalizing the manuscript	were involved in reviewing and finalizing the manuscript	Wrote the paper	Writing - Review & Editing	YES
6055121	30033535	RTM	2	designed and implemented the intervention	designed and implemented the intervention	Conceived and designed the experiments|Performed the experiments	Investigation	YES
6055121	30033535	SJM	2	designed and implemented the intervention	designed and implemented the intervention	Conceived and designed the experiments|Performed the experiments	Investigation	YES
6055121	30033535	SKI	2	were involved in analysing the quantitative data	were involved in analysing the quantitative data	Analyzed the data	Formal analysis	YES
6055121	30033535	SM	2	were involved in reviewing and finalizing the manuscript	were involved in reviewing and finalizing the manuscript	Wrote the paper	Writing - Review & Editing	YES
6055121	30033535	TMK	2	designed and implemented the intervention	designed and implemented the intervention	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5634353	29051766	HC	2	designed the work, drafted the work or revised it critically for important intellectual content	designed the work, drafted the work or revised it critically for important intellectual content	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5634353	29051766	MS	2	revised it critically for important intellectual content	revised it critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5634353	29051766	NC	2	helped with the designed the research and analysis of data for the work with the	helped with the designed the research and analysis of data for the work with the	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5634353	29051766	SQ	2	designed the work, drafted the work or revised it critically for important intellectual content	designed the work, drafted the work or revised it critically for important intellectual content	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5634353	29051766	YW	2	the corresponding author of the manuscript, designed the research and analysis of data for the work with the	the corresponding author of the manuscript, designed the research and analysis of data for the work with the	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5634353	29051766	YY	2	revised it critically for important intellectual content	revised it critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5634353	29051766	ZL	2	revised it critically for important intellectual content	revised it critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
3910228	24472395	All authors	2	were involved in the writing process and all approved the manuscript before submission	were involved in the writing process and all approved the manuscript before submission	Wrote the paper	Writing - Original Draft	YES
3910228	24472395	BW	2	performed the statistical analysis|were involved in the interpretation of the data	performed the statistical analysis	Analyzed the data	Formal analysis	YES
3910228	24472395	BW	2	performed the statistical analysis|were involved in the interpretation of the data	were involved in the interpretation of the data	Analyzed the data	Formal analysis	YES
3910228	24472395	DV	2	contributed to the concept and study design	contributed to the concept and study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
3910228	24472395	EC	2	collected the data	collected the data	Performed the experiments	Investigation	YES
3910228	24472395	GK	2	contributed to the concept and study design|were involved in the interpretation of the data	contributed to the concept and study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
3910228	24472395	GK	2	contributed to the concept and study design|were involved in the interpretation of the data	were involved in the interpretation of the data	Analyzed the data	Formal analysis	YES
3910228	24472395	MJ	2	contributed to the concept and study design|collected the data|performed the statistical analysis|were involved in the interpretation of the data	contributed to the concept and study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
3910228	24472395	MJ	2	contributed to the concept and study design|collected the data|performed the statistical analysis|were involved in the interpretation of the data	collected the data	Performed the experiments	Investigation	YES
3910228	24472395	MJ	2	contributed to the concept and study design|collected the data|performed the statistical analysis|were involved in the interpretation of the data	performed the statistical analysis	Analyzed the data	Formal analysis	YES
3910228	24472395	MJ	2	contributed to the concept and study design|collected the data|performed the statistical analysis|were involved in the interpretation of the data	were involved in the interpretation of the data	Analyzed the data	Formal analysis	YES
3910228	24472395	OH	2	contributed to the concept and study design|collected the data|were involved in the interpretation of the data	contributed to the concept and study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
3910228	24472395	OH	2	contributed to the concept and study design|collected the data|were involved in the interpretation of the data	collected the data	Performed the experiments	Investigation	YES
3910228	24472395	OH	2	contributed to the concept and study design|collected the data|were involved in the interpretation of the data	were involved in the interpretation of the data	Analyzed the data	Formal analysis	YES
3910228	24472395	RB	2	contributed to the concept and study design|were involved in the interpretation of the data	contributed to the concept and study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
3910228	24472395	RB	2	contributed to the concept and study design|were involved in the interpretation of the data	were involved in the interpretation of the data	Analyzed the data	Formal analysis	YES
3910228	24472395	RK	2	contributed to the concept and study design|collected the data|were involved in the interpretation of the data	contributed to the concept and study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
3910228	24472395	RK	2	contributed to the concept and study design|collected the data|were involved in the interpretation of the data	collected the data	Performed the experiments	Investigation	YES
3910228	24472395	RK	2	contributed to the concept and study design|collected the data|were involved in the interpretation of the data	were involved in the interpretation of the data	Analyzed the data	Formal analysis	YES
3910228	24472395	SG	2	collected the data	collected the data	Performed the experiments	Investigation	YES
3910228	24472395	SV	2	collected the data	collected the data	Performed the experiments	Investigation	YES
3910228	24472395	WV	2	contributed to the concept and study design	contributed to the concept and study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409356	25909710	DAB	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409356	25909710	DAB	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409356	25909710	DAB	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409356	25909710	DAB	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409356	25909710	DSC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409356	25909710	DSC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409356	25909710	DSC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409356	25909710	DSC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409356	25909710	DSC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409356	25909710	EVM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409356	25909710	EVM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409356	25909710	EVM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409356	25909710	HW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409356	25909710	HW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409356	25909710	HW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409356	25909710	JH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409356	25909710	JH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409356	25909710	JH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409356	25909710	JH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409356	25909710	JH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409356	25909710	JK	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409356	25909710	JK	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409356	25909710	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409356	25909710	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409356	25909710	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409356	25909710	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409356	25909710	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409356	25909710	MC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409356	25909710	MC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409356	25909710	MC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409356	25909710	MV	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409356	25909710	MV	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409356	25909710	RS	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409356	25909710	RS	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409356	25909710	RS	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409356	25909710	SM	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409356	25909710	SM	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409356	25909710	TJT	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409356	25909710	TJT	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409356	25909710	TJT	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409356	25909710	TN	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409356	25909710	TN	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409356	25909710	XR	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409356	25909710	XR	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5457604	28578697	DAR	PLoS52	conceived and designed the experiments|wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5457604	28578697	DAR	PLoS52	conceived and designed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5457604	28578697	ELT	PLoS52	conceived and designed the experiments|performed the experimental exposure and sampling	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5457604	28578697	ELT	PLoS52	conceived and designed the experiments|performed the experimental exposure and sampling	performed the experimental exposure and sampling	Performed the experiments	Investigation	YES
5457604	28578697	PG	PLoS52	conceived and designed the experiments|performed the experimental exposure and sampling|processed the samples, performed the molecular analyses and analysed the data|wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5457604	28578697	PG	PLoS52	conceived and designed the experiments|performed the experimental exposure and sampling|processed the samples, performed the molecular analyses and analysed the data|wrote the manuscript	performed the experimental exposure and sampling	Performed the experiments	Investigation	YES
5457604	28578697	PG	PLoS52	conceived and designed the experiments|performed the experimental exposure and sampling|processed the samples, performed the molecular analyses and analysed the data|wrote the manuscript	processed the samples, performed the molecular analyses and analysed the data	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5457604	28578697	PG	PLoS52	conceived and designed the experiments|performed the experimental exposure and sampling|processed the samples, performed the molecular analyses and analysed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
1781342	17285143	CB	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1781342	17285143	CB	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6055122	30033537	CW	2	developed the concept for this article|reviewed and commented upon the manuscript at each stage of drafting	developed the concept for this article	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
6055122	30033537	CW	2	developed the concept for this article|reviewed and commented upon the manuscript at each stage of drafting	reviewed and commented upon the manuscript at each stage of drafting	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6055122	30033537	DA	2	developed the concept for this article|reviewed and commented upon the manuscript at each stage of drafting	developed the concept for this article	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
6055122	30033537	DA	2	developed the concept for this article|reviewed and commented upon the manuscript at each stage of drafting	reviewed and commented upon the manuscript at each stage of drafting	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6055122	30033537	JB	2	drafted and edited the manuscript	drafted and edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6055122	30033537	JZ	2	reviewed and commented upon the manuscript at each stage of drafting	reviewed and commented upon the manuscript at each stage of drafting	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6055122	30033537	TL	2	developed the concept for this article|drafted and edited the manuscript	developed the concept for this article	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
6055122	30033537	TL	2	developed the concept for this article|drafted and edited the manuscript	drafted and edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5635682	29056940	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5635682	29056940	HL	2	performed the bioinformatics work	performed the bioinformatics work	Performed the experiments	Formal analysis|Investigation	YES
5635682	29056940	JS	2	conceived the design of the study, analyzed the data and drafted the manuscript	conceived the design of the study, analyzed the data and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
5635682	29056940	KC	2	performed the bioinformatics work|was responsible for data analysis and writing of the manuscript	performed the bioinformatics work	Performed the experiments	Formal analysis|Investigation	YES
5635682	29056940	KC	2	performed the bioinformatics work|was responsible for data analysis and writing of the manuscript	was responsible for data analysis and writing of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5635682	29056940	KY	2	collected and identified samples	collected and identified samples	Performed the experiments	Investigation	YES
5635682	29056940	SH	2	conceived the design of the study, analyzed the data and drafted the manuscript	conceived the design of the study, analyzed the data and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
3937006	24528513	AO	2	participated in producing the figures and writing the article	participated in producing the figures and writing the article	Wrote the paper	Visualization|Writing - Original Draft	YES
3937006	24528513	AW	2	proposed the study and participated in drafting the experiments, performing the experiments, and writing the article	proposed the study and participated in drafting the experiments, performing the experiments, and writing the article	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
3937006	24528513	CM	2	participated in drafting and performing the experiments and writing the article	participated in drafting and performing the experiments and writing the article	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3937006	24528513	CR	2	participated in drafting the in vivo experiments, analyzing the data, and writing the article	participated in drafting the in vivo experiments, analyzing the data, and writing the article	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3937006	24528513	DW	2	proposed the study and participated in drafting the experiments, performing the experiments, and writing the article	proposed the study and participated in drafting the experiments, performing the experiments, and writing the article	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
3937006	24528513	GC	2	participated in drafting the in vivo experiments, analyzing the data, and writing the article	participated in drafting the in vivo experiments, analyzing the data, and writing the article	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3937006	24528513	HM	2	produced the glp1-binding radiopeptide and participated in drafting the experiments and writing the article	produced the glp1-binding radiopeptide and participated in drafting the experiments and writing the article	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3937006	24528513	JR	2	identified the glp1 receptor and participated in drafting the experiments and analyzing the data	identified the glp1 receptor and participated in drafting the experiments and analyzing the data	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3937006	24528513	RM	2	performed the intracellular localization experiments	performed the intracellular localization experiments	Performed the experiments	Investigation	YES
3937006	24528513	VP	2	participated in reviewing the data, producing the figures, and writing the article	participated in reviewing the data, producing the figures, and writing the article	Wrote the paper	Visualization|Writing - Original Draft|Writing - Review & Editing	YES
4409357	25909505	BL	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409357	25909505	BY	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409357	25909505	BY	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409357	25909505	HH	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409357	25909505	HL	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409357	25909505	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409357	25909505	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409357	25909505	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409357	25909505	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409357	25909505	PS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409357	25909505	PS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409357	25909505	PS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409357	25909505	WZ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409357	25909505	WZ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409357	25909505	XX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409357	25909505	XX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409357	25909505	XX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409357	25909505	XX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409357	25909505	YF	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409357	25909505	YZ	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409357	25909505	ZZ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5458484	28583068	AT	2	analyzed the hi-c data|wrote the manuscript|designed and supervised this research project	analyzed the hi-c data	Analyzed the data	Formal analysis	YES
5458484	28583068	AT	2	analyzed the hi-c data|wrote the manuscript|designed and supervised this research project	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5458484	28583068	AT	2	analyzed the hi-c data|wrote the manuscript|designed and supervised this research project	designed and supervised this research project	Conceived and designed the experiments	Methodology|Supervision	YES
5458484	28583068	HH	2	offered expertise on lncrna biology	offered expertise on lncrna biology	-	-	NO
5458484	28583068	IA	2	designed and supervised this research project	designed and supervised this research project	Conceived and designed the experiments	Methodology|Supervision	YES
5458484	28583068	TT	2	offered expertise on lncrna biology|designed an early prototype of the pipeline	offered expertise on lncrna biology	-	-	NO
5458484	28583068	TT	2	offered expertise on lncrna biology|designed an early prototype of the pipeline	designed an early prototype of the pipeline	Conceived and designed the experiments	-	YES
5458484	28583068	YG	2	designed and implemented the pipeline, performed computational analyses, generated figures and wrote the user manual|wrote the manuscript	designed and implemented the pipeline, performed computational analyses, generated figures and wrote the user manual	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Visualization|Writing - Original Draft	YES
5458484	28583068	YG	2	designed and implemented the pipeline, performed computational analyses, generated figures and wrote the user manual|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
1784062	17301878	IJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1784062	17301878	IJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1784062	17301878	IJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1784062	17301878	JP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1784062	17301878	JP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1784062	17301878	JP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1784062	17301878	JP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1784062	17301878	JP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6055123	30033557	AB	2	provided intervention oversight, training and quality assurance	provided intervention oversight, training and quality assurance	Performed the experiments	Supervision|Validation	YES
6055123	30033557	AHD	2	provided intervention oversight, training and quality assurance	provided intervention oversight, training and quality assurance	Performed the experiments	Supervision|Validation	YES
6055123	30033557	BVU	2	were study co-principal investigators|drafted the manuscript with input from the co-authors	were study co-principal investigators	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
6055123	30033557	BVU	2	were study co-principal investigators|drafted the manuscript with input from the co-authors	drafted the manuscript with input from the co-authors	Wrote the paper	Writing - Original Draft	YES
6055123	30033557	GTTH	2	conducted data analysis	conducted data analysis	Analyzed the data	Formal analysis	YES
6055123	30033557	HTTP	2	were study co-principal investigators	were study co-principal investigators	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
6055123	30033557	HVN	2	provided intervention oversight, training and quality assurance	provided intervention oversight, training and quality assurance	Performed the experiments	Supervision|Validation	YES
6055123	30033557	KEG	2	were study co-principal investigators|drafted the manuscript with input from the co-authors	were study co-principal investigators	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
6055123	30033557	KEG	2	were study co-principal investigators|drafted the manuscript with input from the co-authors	drafted the manuscript with input from the co-authors	Wrote the paper	Writing - Original Draft	YES
6055123	30033557	LHD	2	conducted data analysis	conducted data analysis	Analyzed the data	Formal analysis	YES
6055123	30033557	LTXH	2	provided intervention oversight, training and quality assurance	provided intervention oversight, training and quality assurance	Performed the experiments	Supervision|Validation	YES
6055123	30033557	MHT	2	were study co-principal investigators|drafted the manuscript with input from the co-authors|provided data collection oversight|conducted data analysis	were study co-principal investigators	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
6055123	30033557	MHT	2	were study co-principal investigators|drafted the manuscript with input from the co-authors|provided data collection oversight|conducted data analysis	drafted the manuscript with input from the co-authors	Wrote the paper	Writing - Original Draft	YES
6055123	30033557	MHT	2	were study co-principal investigators|drafted the manuscript with input from the co-authors|provided data collection oversight|conducted data analysis	provided data collection oversight	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources|Supervision	YES
6055123	30033557	MHT	2	were study co-principal investigators|drafted the manuscript with input from the co-authors|provided data collection oversight|conducted data analysis	conducted data analysis	Analyzed the data	Formal analysis	YES
6055123	30033557	SHV	2	provided advice and guidance on the intervention design	provided advice and guidance on the intervention design	Conceived and designed the experiments	Supervision	YES
6055123	30033557	TML	2	provided data collection oversight	provided data collection oversight	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources|Supervision	YES
6055123	30033557	TMN	2	provided advice and guidance on the intervention design	provided advice and guidance on the intervention design	Conceived and designed the experiments	Supervision	YES
6055123	30033557	TNNN	2	provided intervention oversight, training and quality assurance	provided intervention oversight, training and quality assurance	Performed the experiments	Supervision|Validation	YES
6055123	30033557	TTD	2	provided data collection oversight	provided data collection oversight	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources|Supervision	YES
6055123	30033557	TTT	2	provided intervention oversight, training and quality assurance	provided intervention oversight, training and quality assurance	Performed the experiments	Supervision|Validation	YES
3763262	24027439	Chih-Yu Lo	2	contributed equally to this work	contributed equally to this work	-	-	NO
3763262	24027439	Po-Len Liu	2	contributed equally to this work	contributed equally to this work	-	-	NO
4409358	25910277	DWE	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409358	25910277	DWE	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409358	25910277	DWE	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409358	25910277	GS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409358	25910277	GS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409358	25910277	GS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409358	25910277	HQ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409358	25910277	HQ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409358	25910277	HQ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409358	25910277	HQ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409358	25910277	HQ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409358	25910277	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409358	25910277	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409358	25910277	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409358	25910277	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409358	25910277	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5635696	29056939	RC-B	2	have substantial contributions to the conception or design of the work, drafting the manuscript, or critically revising it	have substantial contributions to the conception or design of the work, drafting the manuscript, or critically revising it	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
5635696	29056939	SN	2	have substantial contributions to the conception or design of the work, drafting the manuscript, or critically revising it	have substantial contributions to the conception or design of the work, drafting the manuscript, or critically revising it	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
3973855	24602385	AB	2	recruited the patients	recruited the patients	Performed the experiments	Investigation	YES
3973855	24602385	BD	2	did the data analysis and writing of the paper	did the data analysis and writing of the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3973855	24602385	CR	2	recruited the patients	recruited the patients	Performed the experiments	Investigation	YES
3973855	24602385	FDF	2	recruited the patients	recruited the patients	Performed the experiments	Investigation	YES
3973855	24602385	IB	2	developed the method	developed the method	Performed the experiments	Methodology	YES
3973855	24602385	IG	2	developed the method	developed the method	Performed the experiments	Methodology	YES
3973855	24602385	M-EM	2	recruited the patients	recruited the patients	Performed the experiments	Investigation	YES
3973855	24602385	OP	2	did the data analysis and writing of the paper	did the data analysis and writing of the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3973855	24602385	PM	2	designed the study|recruited the patients	designed the study	Conceived and designed the experiments	Methodology	YES
3973855	24602385	PM	2	designed the study|recruited the patients	recruited the patients	Performed the experiments	Investigation	YES
3973855	24602385	PV	2	designed the study|did the data analysis and writing of the paper	designed the study	Conceived and designed the experiments	Methodology	YES
3973855	24602385	PV	2	designed the study|did the data analysis and writing of the paper	did the data analysis and writing of the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3973855	24602385	RM	2	developed the method	developed the method	Performed the experiments	Methodology	YES
3973855	24602385	SB	2	recruited the patients	recruited the patients	Performed the experiments	Investigation	YES
3973855	24602385	SH	2	developed the method	developed the method	Performed the experiments	Methodology	YES
545953	15634361	AK	2	designed microarray, carried out experiments with fish and data analyses and drafted the manuscript	designed microarray, carried out experiments with fish and data analyses and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
545953	15634361	CR	2	constructed the multi-tissue cdna library and provided the selected genes	constructed the multi-tissue cdna library and provided the selected genes	Performed the experiments	Investigation	YES
545953	15634361	HK	2	conducted the microarray analyses	conducted the microarray analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
545953	15634361	HM	2	coordinated research	coordinated research	-	Project administration	YES
545953	15634361	SA	2	developed software for management of microarray data and performed the statistical analyses	developed software for management of microarray data and performed the statistical analyses	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Formal analysis|Investigation|Software	YES
3974015	24606872	AR	2	were involved in the study design, implementation, analysis, and manuscript preparation	were involved in the study design, implementation, analysis, and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
3974015	24606872	CTY	2	were involved in the implementation of the study and manuscript preparation	were involved in the implementation of the study and manuscript preparation	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3974015	24606872	DWT	2	were involved in the study design and manuscript preparation	were involved in the study design and manuscript preparation	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3974015	24606872	EGR	2	were involved in the study design and manuscript preparation	were involved in the study design and manuscript preparation	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3974015	24606872	JDS	2	were involved in the study design, implementation, analysis, and manuscript preparation	were involved in the study design, implementation, analysis, and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
3974015	24606872	JPA	2	were involved in the study design and manuscript preparation	were involved in the study design and manuscript preparation	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3974015	24606872	KK	2	were involved in the implementation of the study and manuscript preparation	were involved in the implementation of the study and manuscript preparation	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3974015	24606872	PC	2	were involved in the study design, implementation, analysis, and manuscript preparation	were involved in the study design, implementation, analysis, and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
6055124	30033612	ABJ	PLoS52	participated in study design|were involved in planning and supervision	participated in study design	Conceived and designed the experiments	Methodology	YES
6055124	30033612	ABJ	PLoS52	participated in study design|were involved in planning and supervision	were involved in planning and supervision	Conceived and designed the experiments	Methodology|Supervision	YES
6055124	30033612	ACFSS	PLoS52	wrote this paper with input from all authors	wrote this paper with input from all authors	Wrote the paper	Writing - Original Draft	YES
6055124	30033612	BG	PLoS52	participated in study design|analysed the data	participated in study design	Conceived and designed the experiments	Methodology	YES
6055124	30033612	BG	PLoS52	participated in study design|analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
6055124	30033612	MC	PLoS52	participated in study design|were involved in planning and supervision	participated in study design	Conceived and designed the experiments	Methodology	YES
6055124	30033612	MC	PLoS52	participated in study design|were involved in planning and supervision	were involved in planning and supervision	Conceived and designed the experiments	Methodology|Supervision	YES
6055124	30033612	NL	PLoS52	were involved in planning and supervision|wrote this paper with input from all authors	were involved in planning and supervision	Conceived and designed the experiments	Methodology|Supervision	YES
6055124	30033612	NL	PLoS52	were involved in planning and supervision|wrote this paper with input from all authors	wrote this paper with input from all authors	Wrote the paper	Writing - Original Draft	YES
6055124	30033612	RBB	PLoS52	participated in study design|were involved in planning and supervision|analysed the data|wrote this paper with input from all authors	participated in study design	Conceived and designed the experiments	Methodology	YES
6055124	30033612	RBB	PLoS52	participated in study design|were involved in planning and supervision|analysed the data|wrote this paper with input from all authors	were involved in planning and supervision	Conceived and designed the experiments	Methodology|Supervision	YES
6055124	30033612	RBB	PLoS52	participated in study design|were involved in planning and supervision|analysed the data|wrote this paper with input from all authors	analysed the data	Analyzed the data	Formal analysis	YES
6055124	30033612	RBB	PLoS52	participated in study design|were involved in planning and supervision|analysed the data|wrote this paper with input from all authors	wrote this paper with input from all authors	Wrote the paper	Writing - Original Draft	YES
6055124	30033612	RGC	PLoS52	were involved in planning and supervision|analysed the data	were involved in planning and supervision	Conceived and designed the experiments	Methodology|Supervision	YES
6055124	30033612	RGC	PLoS52	were involved in planning and supervision|analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
6055124	30033612	TB	PLoS52	wrote this paper with input from all authors	wrote this paper with input from all authors	Wrote the paper	Writing - Original Draft	YES
6055124	30033612	VC	PLoS52	were involved in planning and supervision	were involved in planning and supervision	Conceived and designed the experiments	Methodology|Supervision	YES
6055124	30033612	VGV	PLoS52	participated in study design|analysed the data	participated in study design	Conceived and designed the experiments	Methodology	YES
6055124	30033612	VGV	PLoS52	participated in study design|analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
5635722	29056941	HTsa	2	performed the research	performed the research	Performed the experiments	Investigation	YES
5635722	29056941	HsT	2	designed the research, analyzed the data and wrote the manuscript|participated in data analysis and discussion	designed the research, analyzed the data and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5635722	29056941	HsT	2	designed the research, analyzed the data and wrote the manuscript|participated in data analysis and discussion	participated in data analysis and discussion	Analyzed the data	Formal analysis	YES
3975705	24598405	AKH	2	contributed to the conception and design of the study, carried out the experimental studies and wrote the manuscript	contributed to the conception and design of the study, carried out the experimental studies and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Writing - Original Draft	YES
3975705	24598405	DS	2	contributed to the conception and design of the study, carried out the experimental studies and critically contributed to and revised the manuscript	contributed to the conception and design of the study, carried out the experimental studies and critically contributed to and revised the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Writing - Review & Editing	YES
3975705	24598405	JN	2	contributed to the conception and design of the study, carried out the experimental studies and critically contributed to and revised the manuscript	contributed to the conception and design of the study, carried out the experimental studies and critically contributed to and revised the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Writing - Review & Editing	YES
3975705	24598405	KS	2	contributed to the conception and design of the study, carried out the experimental studies and critically contributed to and revised the manuscript	contributed to the conception and design of the study, carried out the experimental studies and critically contributed to and revised the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Writing - Review & Editing	YES
3975705	24598405	MN	2	contributed to the conception and design of the study, carried out the experimental studies and critically contributed to and revised the manuscript	contributed to the conception and design of the study, carried out the experimental studies and critically contributed to and revised the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Writing - Review & Editing	YES
546001	15631628	DS	2	developed several of the key protocols used in this study	developed several of the key protocols used in this study	Conceived and designed the experiments	Methodology	YES
546001	15631628	GSY	2	was responsible for design and execution of this study, plus analysis of data and drafting of the manuscript	was responsible for design and execution of this study, plus analysis of data and drafting of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
546001	15631628	JMS	2	generated the data described in the study and participated in study design	generated the data described in the study and participated in study design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
546001	15631628	MAM	2	participated in the establishment of the production pipeline and read the manuscript and provided comments	participated in the establishment of the production pipeline and read the manuscript and provided comments	-	-	NO
546001	15631628	MB	2	provided quality assurance of the experimental procedures and participated in study design	provided quality assurance of the experimental procedures and participated in study design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Validation	YES
546001	15631628	RAH	2	conceived of the study and directed the analysis	conceived of the study and directed the analysis	Conceived and designed the experiments	Conceptualization|Supervision	YES
546001	15631628	SAB	2	generated the data described in the study and participated in study design	generated the data described in the study and participated in study design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4409361	25909649	DG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409361	25909649	DG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409361	25909649	DG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409361	25909649	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409361	25909649	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409361	25909649	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409361	25909649	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409361	25909649	RV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409361	25909649	RV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409361	25909649	RV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409361	25909649	RV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409361	25909649	VC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409361	25909649	VC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409361	25909649	VC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409361	25909649	VC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6055125	30033680	AS	2	contributed to the protocol development, training of study staff, manuscript writing	contributed to the protocol development, training of study staff, manuscript writing	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
6055125	30033680	ES	2	managed day-to-day implementation of the intervention and data collection, and contributed to the manuscript writing and review	managed day-to-day implementation of the intervention and data collection, and contributed to the manuscript writing and review	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
6055125	30033680	JN	2	assisted with implementation oversight and manuscript review	assisted with implementation oversight and manuscript review	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Review & Editing	YES
6055125	30033680	KOLs	2	supervised data collection and contributed to the manuscript writing and review|conducted the data analysis and led the manuscript writing	supervised data collection and contributed to the manuscript writing and review	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
6055125	30033680	KOLs	2	supervised data collection and contributed to the manuscript writing and review|conducted the data analysis and led the manuscript writing	conducted the data analysis and led the manuscript writing	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6055125	30033680	LV	2	conceptualized the study design|assisted with protocol and tool development, quantitative data analysis and contributed to manuscript writing	conceptualized the study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6055125	30033680	LV	2	conceptualized the study design|assisted with protocol and tool development, quantitative data analysis and contributed to manuscript writing	assisted with protocol and tool development, quantitative data analysis and contributed to manuscript writing	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Original Draft	YES
6055125	30033680	SA	2	conceptualized the study design	conceptualized the study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6055125	30033680	WT	2	conceptualized the study design	conceptualized the study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
1784064	17299585	AD	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1784064	17299585	AD	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1784064	17299585	AP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1784064	17299585	AP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1784064	17299585	AP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1784064	17299585	AP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1784064	17299585	AR	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1784064	17299585	AR	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1784064	17299585	CI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1784064	17299585	CI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1784064	17299585	CI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1784064	17299585	MF	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1784064	17299585	MF	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1784064	17299585	RA	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1784064	17299585	RA	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3976537	24593883	AS	2	performed the clinical studies	performed the clinical studies	Performed the experiments	Investigation	YES
3976537	24593883	HI	2	performed the clinical studies	performed the clinical studies	Performed the experiments	Investigation	YES
3976537	24593883	JT	2	are responsible for the study concepts and design|participated in the literature research|did the manuscript preparation|participated in the manuscript revision/review	are responsible for the study concepts and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
3976537	24593883	JT	2	are responsible for the study concepts and design|participated in the literature research|did the manuscript preparation|participated in the manuscript revision/review	participated in the literature research	-	Formal analysis	YES
3976537	24593883	JT	2	are responsible for the study concepts and design|participated in the literature research|did the manuscript preparation|participated in the manuscript revision/review	did the manuscript preparation	Wrote the paper	Writing - Original Draft	YES
3976537	24593883	JT	2	are responsible for the study concepts and design|participated in the literature research|did the manuscript preparation|participated in the manuscript revision/review	participated in the manuscript revision/review	Wrote the paper	Writing - Review & Editing	YES
3976537	24593883	KI	2	are responsible for the study concepts and design|participated in the literature research|participated in the literature research|did the manuscript preparation|did the manuscript preparation|participated in the manuscript revision/review|participated in the manuscript revision/review	are responsible for the study concepts and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
3976537	24593883	KI	2	are responsible for the study concepts and design|participated in the literature research|participated in the literature research|did the manuscript preparation|did the manuscript preparation|participated in the manuscript revision/review|participated in the manuscript revision/review	participated in the literature research	-	Formal analysis	YES
3976537	24593883	KI	2	are responsible for the study concepts and design|participated in the literature research|participated in the literature research|did the manuscript preparation|did the manuscript preparation|participated in the manuscript revision/review|participated in the manuscript revision/review	participated in the literature research	-	Formal analysis	YES
3976537	24593883	KI	2	are responsible for the study concepts and design|participated in the literature research|participated in the literature research|did the manuscript preparation|did the manuscript preparation|participated in the manuscript revision/review|participated in the manuscript revision/review	did the manuscript preparation	Wrote the paper	Writing - Original Draft	YES
3976537	24593883	KI	2	are responsible for the study concepts and design|participated in the literature research|participated in the literature research|did the manuscript preparation|did the manuscript preparation|participated in the manuscript revision/review|participated in the manuscript revision/review	did the manuscript preparation	Wrote the paper	Writing - Original Draft	YES
3976537	24593883	KI	2	are responsible for the study concepts and design|participated in the literature research|participated in the literature research|did the manuscript preparation|did the manuscript preparation|participated in the manuscript revision/review|participated in the manuscript revision/review	participated in the manuscript revision/review	Wrote the paper	Writing - Review & Editing	YES
3976537	24593883	KI	2	are responsible for the study concepts and design|participated in the literature research|participated in the literature research|did the manuscript preparation|did the manuscript preparation|participated in the manuscript revision/review|participated in the manuscript revision/review	participated in the manuscript revision/review	Wrote the paper	Writing - Review & Editing	YES
3976537	24593883	KK	2	are guarantors of integrity of the entire study|are responsible for the study concepts and design|participated in the literature research|performed the clinical studies|performed the data analysis/interpretation|did the manuscript preparation|participated in the manuscript revision/review	are guarantors of integrity of the entire study	-	-	NO
3976537	24593883	KK	2	are guarantors of integrity of the entire study|are responsible for the study concepts and design|participated in the literature research|performed the clinical studies|performed the data analysis/interpretation|did the manuscript preparation|participated in the manuscript revision/review	are responsible for the study concepts and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
3976537	24593883	KK	2	are guarantors of integrity of the entire study|are responsible for the study concepts and design|participated in the literature research|performed the clinical studies|performed the data analysis/interpretation|did the manuscript preparation|participated in the manuscript revision/review	participated in the literature research	-	Formal analysis	YES
3976537	24593883	KK	2	are guarantors of integrity of the entire study|are responsible for the study concepts and design|participated in the literature research|performed the clinical studies|performed the data analysis/interpretation|did the manuscript preparation|participated in the manuscript revision/review	performed the clinical studies	Performed the experiments	Investigation	YES
3976537	24593883	KK	2	are guarantors of integrity of the entire study|are responsible for the study concepts and design|participated in the literature research|performed the clinical studies|performed the data analysis/interpretation|did the manuscript preparation|participated in the manuscript revision/review	performed the data analysis/interpretation	Analyzed the data	Formal analysis	YES
3976537	24593883	KK	2	are guarantors of integrity of the entire study|are responsible for the study concepts and design|participated in the literature research|performed the clinical studies|performed the data analysis/interpretation|did the manuscript preparation|participated in the manuscript revision/review	did the manuscript preparation	Wrote the paper	Writing - Original Draft	YES
3976537	24593883	KK	2	are guarantors of integrity of the entire study|are responsible for the study concepts and design|participated in the literature research|performed the clinical studies|performed the data analysis/interpretation|did the manuscript preparation|participated in the manuscript revision/review	participated in the manuscript revision/review	Wrote the paper	Writing - Review & Editing	YES
3976537	24593883	KN	2	performed the clinical studies	performed the clinical studies	Performed the experiments	Investigation	YES
3976537	24593883	MM	2	performed the data analysis/interpretation	performed the data analysis/interpretation	Analyzed the data	Formal analysis	YES
3976537	24593883	MO	2	performed the clinical studies|performed the data analysis/interpretation	performed the clinical studies	Performed the experiments	Investigation	YES
3976537	24593883	MO	2	performed the clinical studies|performed the data analysis/interpretation	performed the data analysis/interpretation	Analyzed the data	Formal analysis	YES
3976537	24593883	RM	2	are guarantors of integrity of the entire study|are responsible for the study concepts and design|participated in the literature research|performed the clinical studies|performed the data analysis/interpretation|did the manuscript preparation|participated in the manuscript revision/review	are guarantors of integrity of the entire study	-	-	NO
3976537	24593883	RM	2	are guarantors of integrity of the entire study|are responsible for the study concepts and design|participated in the literature research|performed the clinical studies|performed the data analysis/interpretation|did the manuscript preparation|participated in the manuscript revision/review	are responsible for the study concepts and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
3976537	24593883	RM	2	are guarantors of integrity of the entire study|are responsible for the study concepts and design|participated in the literature research|performed the clinical studies|performed the data analysis/interpretation|did the manuscript preparation|participated in the manuscript revision/review	participated in the literature research	-	Formal analysis	YES
3976537	24593883	RM	2	are guarantors of integrity of the entire study|are responsible for the study concepts and design|participated in the literature research|performed the clinical studies|performed the data analysis/interpretation|did the manuscript preparation|participated in the manuscript revision/review	performed the clinical studies	Performed the experiments	Investigation	YES
3976537	24593883	RM	2	are guarantors of integrity of the entire study|are responsible for the study concepts and design|participated in the literature research|performed the clinical studies|performed the data analysis/interpretation|did the manuscript preparation|participated in the manuscript revision/review	performed the data analysis/interpretation	Analyzed the data	Formal analysis	YES
3976537	24593883	RM	2	are guarantors of integrity of the entire study|are responsible for the study concepts and design|participated in the literature research|performed the clinical studies|performed the data analysis/interpretation|did the manuscript preparation|participated in the manuscript revision/review	did the manuscript preparation	Wrote the paper	Writing - Original Draft	YES
3976537	24593883	RM	2	are guarantors of integrity of the entire study|are responsible for the study concepts and design|participated in the literature research|performed the clinical studies|performed the data analysis/interpretation|did the manuscript preparation|participated in the manuscript revision/review	participated in the manuscript revision/review	Wrote the paper	Writing - Review & Editing	YES
3976537	24593883	YM	2	performed the data analysis/interpretation	performed the data analysis/interpretation	Analyzed the data	Formal analysis	YES
5640704	29062319	All authors	2	discussed the results and commented on the manuscript	discussed the results and commented on the manuscript	-	-	NO
5640704	29062319	MR	2	conceived of the manuscript|edited the manuscript	conceived of the manuscript	Conceived and designed the experiments	Conceptualization	YES
5640704	29062319	MR	2	conceived of the manuscript|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5640704	29062319	MT	2	conceived of the manuscript|conducted all experiments	conceived of the manuscript	Conceived and designed the experiments	Conceptualization	YES
5640704	29062319	MT	2	conceived of the manuscript|conducted all experiments	conducted all experiments	Performed the experiments	Investigation	YES
5640704	29062319	NM	2	conducted all experiments	conducted all experiments	Performed the experiments	Investigation	YES
4409362	25909656	FXT	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409362	25909656	FXT	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409362	25909656	FXT	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409362	25909656	FXT	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409362	25909656	JJH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409362	25909656	JJH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409362	25909656	JJH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409362	25909656	JJH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409362	25909656	JLZ	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409362	25909656	JZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409362	25909656	JZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409362	25909656	JZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409362	25909656	JZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409362	25909656	JZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409362	25909656	TW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409362	25909656	YLX	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4548067	26347885	Jiang Wu	2	had equal contribution and are designated as co-first authors	had equal contribution and are designated as co-first authors	Conceived and designed the experiments	-	YES
546002	15651988	AND	2	carried out the cdna library construction, microarray fabrication, data analysis, and drafted the manuscript	carried out the cdna library construction, microarray fabrication, data analysis, and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
546002	15651988	BWH	2	constructed the microarray genechips and carried out microarray data acquisition	constructed the microarray genechips and carried out microarray data acquisition	Performed the experiments	Investigation	YES
546002	15651988	JRH	2	maintained and provided mosquito samples throughout the project	maintained and provided mosquito samples throughout the project	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
546002	15651988	YSH	2	performed the microarray experiment, data analysis, and helped draft the manuscript|to draft the manuscript and reviewed it	performed the microarray experiment, data analysis, and helped draft the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
546002	15651988	YSH	2	performed the microarray experiment, data analysis, and helped draft the manuscript|to draft the manuscript and reviewed it	to draft the manuscript and reviewed it	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6055127	30033589	AB	2	contributed to developing the study concept and design|contributed to data collection	contributed to developing the study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6055127	30033589	AB	2	contributed to developing the study concept and design|contributed to data collection	contributed to data collection	Performed the experiments	Investigation	YES
6055127	30033589	All authors	2	reviewed the manuscript critically for intellectual content	reviewed the manuscript critically for intellectual content	Wrote the paper	Writing - Review & Editing	YES
6055127	30033589	IM	2	contributed to developing the study concept and design	contributed to developing the study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6055127	30033589	JEL	2	assisted with data analysis and results interpretation	assisted with data analysis and results interpretation	Analyzed the data	Formal analysis	YES
6055127	30033589	JKE	2	contributed to developing the study concept and design	contributed to developing the study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6055127	30033589	KEL	2	contributed to developing the study concept and design	contributed to developing the study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6055127	30033589	MEH	2	had overall responsibility for implementing the study, and conceived and designed the study, analysed the data, and led the manuscript writing|contributed to developing the study concept and design|contributed to drafting the manuscript	had overall responsibility for implementing the study, and conceived and designed the study, analysed the data, and led the manuscript writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
6055127	30033589	MEH	2	had overall responsibility for implementing the study, and conceived and designed the study, analysed the data, and led the manuscript writing|contributed to developing the study concept and design|contributed to drafting the manuscript	contributed to developing the study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6055127	30033589	MEH	2	had overall responsibility for implementing the study, and conceived and designed the study, analysed the data, and led the manuscript writing|contributed to developing the study concept and design|contributed to drafting the manuscript	contributed to drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
6055127	30033589	PS	2	contributed to data collection	contributed to data collection	Performed the experiments	Investigation	YES
6055127	30033589	SSW	2	had overall responsibility for implementing the study, and conceived and designed the study, analysed the data, and led the manuscript writing|contributed to developing the study concept and design|contributed to data collection|assisted with data analysis and results interpretation|contributed to drafting the manuscript	had overall responsibility for implementing the study, and conceived and designed the study, analysed the data, and led the manuscript writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
6055127	30033589	SSW	2	had overall responsibility for implementing the study, and conceived and designed the study, analysed the data, and led the manuscript writing|contributed to developing the study concept and design|contributed to data collection|assisted with data analysis and results interpretation|contributed to drafting the manuscript	contributed to developing the study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6055127	30033589	SSW	2	had overall responsibility for implementing the study, and conceived and designed the study, analysed the data, and led the manuscript writing|contributed to developing the study concept and design|contributed to data collection|assisted with data analysis and results interpretation|contributed to drafting the manuscript	contributed to data collection	Performed the experiments	Investigation	YES
6055127	30033589	SSW	2	had overall responsibility for implementing the study, and conceived and designed the study, analysed the data, and led the manuscript writing|contributed to developing the study concept and design|contributed to data collection|assisted with data analysis and results interpretation|contributed to drafting the manuscript	assisted with data analysis and results interpretation	Analyzed the data	Formal analysis	YES
6055127	30033589	SSW	2	had overall responsibility for implementing the study, and conceived and designed the study, analysed the data, and led the manuscript writing|contributed to developing the study concept and design|contributed to data collection|assisted with data analysis and results interpretation|contributed to drafting the manuscript	contributed to drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
6055127	30033589	WM	2	contributed to drafting the manuscript	contributed to drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
6055127	30033589	WMM	2	had overall responsibility for implementing the study, and conceived and designed the study, analysed the data, and led the manuscript writing|contributed to developing the study concept and design|contributed to data collection|assisted with data analysis and results interpretation	had overall responsibility for implementing the study, and conceived and designed the study, analysed the data, and led the manuscript writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
6055127	30033589	WMM	2	had overall responsibility for implementing the study, and conceived and designed the study, analysed the data, and led the manuscript writing|contributed to developing the study concept and design|contributed to data collection|assisted with data analysis and results interpretation	contributed to developing the study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6055127	30033589	WMM	2	had overall responsibility for implementing the study, and conceived and designed the study, analysed the data, and led the manuscript writing|contributed to developing the study concept and design|contributed to data collection|assisted with data analysis and results interpretation	contributed to data collection	Performed the experiments	Investigation	YES
6055127	30033589	WMM	2	had overall responsibility for implementing the study, and conceived and designed the study, analysed the data, and led the manuscript writing|contributed to developing the study concept and design|contributed to data collection|assisted with data analysis and results interpretation	assisted with data analysis and results interpretation	Analyzed the data	Formal analysis	YES
1784065	17299586	AX	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1784065	17299586	AX	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1784065	17299586	AX	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1784065	17299586	CM	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1784065	17299586	CM	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1784065	17299586	GH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1784065	17299586	GH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1784065	17299586	GH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1784065	17299586	GH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1784065	17299586	HL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1784065	17299586	JC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1784065	17299586	JL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1784065	17299586	LF	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1784065	17299586	LG	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1784065	17299586	MD	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1784065	17299586	QZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1784065	17299586	SC	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1784065	17299586	XX	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1784065	17299586	XX	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1784065	17299586	YH	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1784065	17299586	YH	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
3986910	24670127	ES	2	conceived and coordinated the study and drafted the manuscript|conducted the in vivo metabolism study	conceived and coordinated the study and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Project administration|Writing - Original Draft	YES
3986910	24670127	ES	2	conceived and coordinated the study and drafted the manuscript|conducted the in vivo metabolism study	conducted the in vivo metabolism study	Performed the experiments	Investigation	YES
3986910	24670127	HR	2	conceived and coordinated the study and drafted the manuscript|performed the pet examinations and ex vivo studies	conceived and coordinated the study and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Project administration|Writing - Original Draft	YES
3986910	24670127	HR	2	conceived and coordinated the study and drafted the manuscript|performed the pet examinations and ex vivo studies	performed the pet examinations and ex vivo studies	Performed the experiments	Investigation	YES
3986910	24670127	JM	2	performed the immunohistochemistry studies	performed the immunohistochemistry studies	Performed the experiments	Investigation	YES
3986910	24670127	LH	2	conceived and coordinated the study and drafted the manuscript	conceived and coordinated the study and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Project administration|Writing - Original Draft	YES
3986910	24670127	LL	2	performed the pet examinations and ex vivo studies|conducted the in vivo metabolism study	performed the pet examinations and ex vivo studies	Performed the experiments	Investigation	YES
3986910	24670127	LL	2	performed the pet examinations and ex vivo studies|conducted the in vivo metabolism study	conducted the in vivo metabolism study	Performed the experiments	Investigation	YES
3986910	24670127	PD	2	carried out the mri examinations	carried out the mri examinations	Performed the experiments	Investigation	YES
3986910	24670127	SSE	2	conceived and coordinated the study and drafted the manuscript	conceived and coordinated the study and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Project administration|Writing - Original Draft	YES
3986910	24670127	TT	2	conceived and coordinated the study and drafted the manuscript	conceived and coordinated the study and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Project administration|Writing - Original Draft	YES
4409363	25909964	BGL	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409363	25909964	BGL	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409363	25909964	DHC	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409363	25909964	DHC	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409363	25909964	HLFC	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409363	25909964	MLH	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409363	25909964	MLH	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409363	25909964	MRK	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409363	25909964	RSG	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409363	25909964	SC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409363	25909964	SC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409363	25909964	SC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409363	25909964	SC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409363	25909964	SIS-D	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409363	25909964	SIS-D	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409363	25909964	SMW	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5640774	29062321	CL	CRediT	Manuscript preparation|Supervision	Manuscript preparation	Wrote the paper	Writing - Original Draft	YES
5640774	29062321	CL	CRediT	Manuscript preparation|Supervision	Supervision	-	Supervision	YES
5640774	29062321	JL	CRediT	Experimental design|Supervision|Funding	Experimental design	Conceived and designed the experiments	Methodology	YES
5640774	29062321	JL	CRediT	Experimental design|Supervision|Funding	Supervision	-	Supervision	YES
5640774	29062321	JL	CRediT	Experimental design|Supervision|Funding	Funding	-	Funding acquisition	YES
5640774	29062321	RM	CRediT	Experimental design|Experiments implementation|Data analysis|Manuscript preparation|Funding	Experimental design	Conceived and designed the experiments	Methodology	YES
5640774	29062321	RM	CRediT	Experimental design|Experiments implementation|Data analysis|Manuscript preparation|Funding	Experiments implementation	Performed the experiments	Investigation	YES
5640774	29062321	RM	CRediT	Experimental design|Experiments implementation|Data analysis|Manuscript preparation|Funding	Data analysis	Analyzed the data	Formal analysis	YES
5640774	29062321	RM	CRediT	Experimental design|Experiments implementation|Data analysis|Manuscript preparation|Funding	Manuscript preparation	Wrote the paper	Writing - Original Draft	YES
5640774	29062321	RM	CRediT	Experimental design|Experiments implementation|Data analysis|Manuscript preparation|Funding	Funding	-	Funding acquisition	YES
5640774	29062321	XH	CRediT	Manuscript preparation	Manuscript preparation	Wrote the paper	Writing - Original Draft	YES
5640774	29062321	YZ	CRediT	Manuscript preparation	Manuscript preparation	Wrote the paper	Writing - Original Draft	YES
3992152	24693879	AL	2	performed part of the data analysis	performed part of the data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3992152	24693879	BBB	2	selected the patient studies and performed the lesion delineation	selected the patient studies and performed the lesion delineation	Performed the experiments	Investigation	YES
3992152	24693879	FH	2	performed part of the data analysis and wrote part of the manuscript	performed part of the data analysis and wrote part of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3992152	24693879	GS	2	performed part of the data analysis	performed part of the data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3992152	24693879	JK	2	provided intellectual input and reviewed the manuscript	provided intellectual input and reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
3992152	24693879	JM	2	provided intellectual input and reviewed the manuscript	provided intellectual input and reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
3992152	24693879	JP	2	provided intellectual input and reviewed the manuscript	provided intellectual input and reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
3992152	24693879	LO	2	provided intellectual input and reviewed the manuscript	provided intellectual input and reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
3992152	24693879	SUR	2	performed part of the data analysis, and wrote part of the manuscript	performed part of the data analysis, and wrote part of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3992152	24693879	SUV	2	performed part of the data analysis, and wrote part of the manuscript	performed part of the data analysis, and wrote part of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6055128	30033654	AH	2	conceived of this manuscript|contributed substantially to the writing	conceived of this manuscript	Conceived and designed the experiments	Conceptualization	YES
6055128	30033654	AH	2	conceived of this manuscript|contributed substantially to the writing	contributed substantially to the writing	Wrote the paper	-	YES
6055128	30033654	DP	2	conceived of this manuscript|reviewed the manuscript	conceived of this manuscript	Conceived and designed the experiments	Conceptualization	YES
6055128	30033654	DP	2	conceived of this manuscript|reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
6055128	30033654	JB	2	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
6055128	30033654	JC	2	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
6055128	30033654	JZ	2	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
6055128	30033654	KS	2	conceived of this manuscript|reviewed the manuscript	conceived of this manuscript	Conceived and designed the experiments	Conceptualization	YES
6055128	30033654	KS	2	conceived of this manuscript|reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
6055128	30033654	VM	2	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
6055128	30033654	WH	2	conceived of this manuscript|contributed substantially to the writing	conceived of this manuscript	Conceived and designed the experiments	Conceptualization	YES
6055128	30033654	WH	2	conceived of this manuscript|contributed substantially to the writing	contributed substantially to the writing	Wrote the paper	-	YES
5460339	28583082	AC	PLoS5	Built the bioinformatic infrastructure for data access	Built the bioinformatic infrastructure for data access	-	Formal analysis	YES
5460339	28583082	BQ-T	PLoS5	Conceived and designed the experiments|Performed experiments|Contributed reagents/materials/analysis tools|Critically revised the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5460339	28583082	BQ-T	PLoS5	Conceived and designed the experiments|Performed experiments|Contributed reagents/materials/analysis tools|Critically revised the manuscript	Performed experiments	Performed the experiments	Investigation	YES
5460339	28583082	BQ-T	PLoS5	Conceived and designed the experiments|Performed experiments|Contributed reagents/materials/analysis tools|Critically revised the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5460339	28583082	BQ-T	PLoS5	Conceived and designed the experiments|Performed experiments|Contributed reagents/materials/analysis tools|Critically revised the manuscript	Critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5460339	28583082	CC	PLoS5	Performed experiments	Performed experiments	Performed the experiments	Investigation	YES
5460339	28583082	DB	PLoS5	Conceived and designed the experiments|Performed experiments|Contributed reagents/materials/analysis tools|Critically revised the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5460339	28583082	DB	PLoS5	Conceived and designed the experiments|Performed experiments|Contributed reagents/materials/analysis tools|Critically revised the manuscript	Performed experiments	Performed the experiments	Investigation	YES
5460339	28583082	DB	PLoS5	Conceived and designed the experiments|Performed experiments|Contributed reagents/materials/analysis tools|Critically revised the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5460339	28583082	DB	PLoS5	Conceived and designed the experiments|Performed experiments|Contributed reagents/materials/analysis tools|Critically revised the manuscript	Critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5460339	28583082	DM	PLoS5	Performed experiments|Analyzed the data|Critically revised the manuscript	Performed experiments	Performed the experiments	Investigation	YES
5460339	28583082	DM	PLoS5	Performed experiments|Analyzed the data|Critically revised the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
5460339	28583082	DM	PLoS5	Performed experiments|Analyzed the data|Critically revised the manuscript	Critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5460339	28583082	EB	PLoS5	Performed experiments|Contributed reagents/materials/analysis tools	Performed experiments	Performed the experiments	Investigation	YES
5460339	28583082	EB	PLoS5	Performed experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5460339	28583082	ED	PLoS5	Conceived and designed the experiments|Performed experiments|Contributed reagents/materials/analysis tools|Critically revised the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5460339	28583082	ED	PLoS5	Conceived and designed the experiments|Performed experiments|Contributed reagents/materials/analysis tools|Critically revised the manuscript	Performed experiments	Performed the experiments	Investigation	YES
5460339	28583082	ED	PLoS5	Conceived and designed the experiments|Performed experiments|Contributed reagents/materials/analysis tools|Critically revised the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5460339	28583082	ED	PLoS5	Conceived and designed the experiments|Performed experiments|Contributed reagents/materials/analysis tools|Critically revised the manuscript	Critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5460339	28583082	EVW	PLoS5	Performed experiments|Contributed reagents/materials/analysis tools|Critically revised the manuscript	Performed experiments	Performed the experiments	Investigation	YES
5460339	28583082	EVW	PLoS5	Performed experiments|Contributed reagents/materials/analysis tools|Critically revised the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5460339	28583082	EVW	PLoS5	Performed experiments|Contributed reagents/materials/analysis tools|Critically revised the manuscript	Critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5460339	28583082	FL	PLoS5	Conceived and designed the experiments|Critically revised the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5460339	28583082	FL	PLoS5	Conceived and designed the experiments|Critically revised the manuscript	Critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5460339	28583082	IV	PLoS5	Conceived and designed the experiments|Performed experiments|Contributed reagents/materials/analysis tools|Critically revised the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5460339	28583082	IV	PLoS5	Conceived and designed the experiments|Performed experiments|Contributed reagents/materials/analysis tools|Critically revised the manuscript	Performed experiments	Performed the experiments	Investigation	YES
5460339	28583082	IV	PLoS5	Conceived and designed the experiments|Performed experiments|Contributed reagents/materials/analysis tools|Critically revised the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5460339	28583082	IV	PLoS5	Conceived and designed the experiments|Performed experiments|Contributed reagents/materials/analysis tools|Critically revised the manuscript	Critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5460339	28583082	JAC	PLoS5	Performed experiments	Performed experiments	Performed the experiments	Investigation	YES
5460339	28583082	JRHM	PLoS5	Performed experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed experiments	Performed the experiments	Investigation	YES
5460339	28583082	JRHM	PLoS5	Performed experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5460339	28583082	JRHM	PLoS5	Performed experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5460339	28583082	JRHM	PLoS5	Performed experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5460339	28583082	LR	PLoS5	Conceived and designed the experiments|Performed experiments|Contributed reagents/materials/analysis tools|Critically revised the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5460339	28583082	LR	PLoS5	Conceived and designed the experiments|Performed experiments|Contributed reagents/materials/analysis tools|Critically revised the manuscript	Performed experiments	Performed the experiments	Investigation	YES
5460339	28583082	LR	PLoS5	Conceived and designed the experiments|Performed experiments|Contributed reagents/materials/analysis tools|Critically revised the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5460339	28583082	LR	PLoS5	Conceived and designed the experiments|Performed experiments|Contributed reagents/materials/analysis tools|Critically revised the manuscript	Critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5460339	28583082	MB	PLoS5	Performed experiments|Contributed reagents/materials/analysis tools	Performed experiments	Performed the experiments	Investigation	YES
5460339	28583082	MB	PLoS5	Performed experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5460339	28583082	MJA	PLoS5	Conceived and designed the experiments|Performed experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5460339	28583082	MJA	PLoS5	Conceived and designed the experiments|Performed experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed experiments	Performed the experiments	Investigation	YES
5460339	28583082	MJA	PLoS5	Conceived and designed the experiments|Performed experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5460339	28583082	MJA	PLoS5	Conceived and designed the experiments|Performed experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5460339	28583082	MJA	PLoS5	Conceived and designed the experiments|Performed experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5460339	28583082	MT	PLoS5	Performed experiments|Contributed reagents/materials/analysis tools|Critically revised the manuscript	Performed experiments	Performed the experiments	Investigation	YES
5460339	28583082	MT	PLoS5	Performed experiments|Contributed reagents/materials/analysis tools|Critically revised the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5460339	28583082	MT	PLoS5	Performed experiments|Contributed reagents/materials/analysis tools|Critically revised the manuscript	Critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5460339	28583082	MTD	PLoS5	Performed experiments|Critically revised the manuscript	Performed experiments	Performed the experiments	Investigation	YES
5460339	28583082	MTD	PLoS5	Performed experiments|Critically revised the manuscript	Critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5460339	28583082	NN	PLoS5	Built the bioinformatic infrastructure for data access	Built the bioinformatic infrastructure for data access	-	Formal analysis	YES
5460339	28583082	PA	PLoS5	Conceived and designed the experiments|Performed experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5460339	28583082	PA	PLoS5	Conceived and designed the experiments|Performed experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed experiments	Performed the experiments	Investigation	YES
5460339	28583082	PA	PLoS5	Conceived and designed the experiments|Performed experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5460339	28583082	PA	PLoS5	Conceived and designed the experiments|Performed experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5460339	28583082	PA	PLoS5	Conceived and designed the experiments|Performed experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5460339	28583082	PL	PLoS5	Conceived and designed the experiments|Performed experiments|Contributed reagents/materials/analysis tools|Critically revised the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5460339	28583082	PL	PLoS5	Conceived and designed the experiments|Performed experiments|Contributed reagents/materials/analysis tools|Critically revised the manuscript	Performed experiments	Performed the experiments	Investigation	YES
5460339	28583082	PL	PLoS5	Conceived and designed the experiments|Performed experiments|Contributed reagents/materials/analysis tools|Critically revised the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5460339	28583082	PL	PLoS5	Conceived and designed the experiments|Performed experiments|Contributed reagents/materials/analysis tools|Critically revised the manuscript	Critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5460339	28583082	SM	PLoS5	Performed experiments|Critically revised the manuscript	Performed experiments	Performed the experiments	Investigation	YES
5460339	28583082	SM	PLoS5	Performed experiments|Critically revised the manuscript	Critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5460339	28583082	TP	PLoS5	Conceived and designed the experiments|Performed experiments|Contributed reagents/materials/analysis tools|Critically revised the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5460339	28583082	TP	PLoS5	Conceived and designed the experiments|Performed experiments|Contributed reagents/materials/analysis tools|Critically revised the manuscript	Performed experiments	Performed the experiments	Investigation	YES
5460339	28583082	TP	PLoS5	Conceived and designed the experiments|Performed experiments|Contributed reagents/materials/analysis tools|Critically revised the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5460339	28583082	TP	PLoS5	Conceived and designed the experiments|Performed experiments|Contributed reagents/materials/analysis tools|Critically revised the manuscript	Critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
1784067	17299588	GA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1784067	17299588	GA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1784067	17299588	GA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1784067	17299588	GLA	PLoS5	Jointly conceived the project and carried out the fieldwork|Did the image analysis, statistical analyses and drafted and finalized the manuscript	Jointly conceived the project and carried out the fieldwork	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
1784067	17299588	GLA	PLoS5	Jointly conceived the project and carried out the fieldwork|Did the image analysis, statistical analyses and drafted and finalized the manuscript	Did the image analysis, statistical analyses and drafted and finalized the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Visualization|Writing - Original Draft|Writing - Review & Editing	YES
1784067	17299588	KK	PLoS5	Conceived and designed the experiments|Wrote the paper|Jointly conceived the project and carried out the fieldwork|Contributed to the finalization of the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1784067	17299588	KK	PLoS5	Conceived and designed the experiments|Wrote the paper|Jointly conceived the project and carried out the fieldwork|Contributed to the finalization of the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1784067	17299588	KK	PLoS5	Conceived and designed the experiments|Wrote the paper|Jointly conceived the project and carried out the fieldwork|Contributed to the finalization of the manuscript	Jointly conceived the project and carried out the fieldwork	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
1784067	17299588	KK	PLoS5	Conceived and designed the experiments|Wrote the paper|Jointly conceived the project and carried out the fieldwork|Contributed to the finalization of the manuscript	Contributed to the finalization of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4409364	25910041	AMB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409364	25910041	AMB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409364	25910041	AMB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409364	25910041	BL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409364	25910041	BL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409364	25910041	BL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409364	25910041	BL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409364	25910041	BL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409364	25910041	CT	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409364	25910041	CT	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409364	25910041	CT	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409364	25910041	DB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409364	25910041	DB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409364	25910041	DB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409364	25910041	FDB	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409364	25910041	LM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409364	25910041	LM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409364	25910041	LM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409364	25910041	MRM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409364	25910041	MRM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409364	25910041	MRM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409364	25910041	MRM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409364	25910041	SL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409364	25910041	SL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409364	25910041	SL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409364	25910041	SL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409364	25910041	SL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3995622	24620906	All authors	2	reviewed and approved the final manuscript	reviewed and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
3995622	24620906	CB	2	supervised and coordinated the study and manuscript preparation	supervised and coordinated the study and manuscript preparation	Wrote the paper	Project administration|Supervision|Writing - Original Draft	YES
3995622	24620906	CH	2	performed radiation dosage estimation base on the imaging data|participated in the writing	performed radiation dosage estimation base on the imaging data	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
3995622	24620906	CH	2	performed radiation dosage estimation base on the imaging data|participated in the writing	participated in the writing	Wrote the paper	-	YES
3995622	24620906	DD	2	contributed to the synthesis of the tracer|were responsible for the imaging study and ex vivo tissue assays	contributed to the synthesis of the tracer	-	-	NO
3995622	24620906	DD	2	contributed to the synthesis of the tracer|were responsible for the imaging study and ex vivo tissue assays	were responsible for the imaging study and ex vivo tissue assays	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
3995622	24620906	JL	2	were responsible for the imaging study and ex vivo tissue assays|participated in the writing	were responsible for the imaging study and ex vivo tissue assays	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
3995622	24620906	JL	2	were responsible for the imaging study and ex vivo tissue assays|participated in the writing	participated in the writing	Wrote the paper	-	YES
3995622	24620906	KS	2	wrote and tested the image quantification program and performed image analyses	wrote and tested the image quantification program and performed image analyses	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Software|Visualization|Writing - Original Draft	YES
3995622	24620906	LW	2	contributed to the synthesis of the tracer|were responsible for the imaging study and ex vivo tissue assays|participated in the writing	contributed to the synthesis of the tracer	-	-	NO
3995622	24620906	LW	2	contributed to the synthesis of the tracer|were responsible for the imaging study and ex vivo tissue assays|participated in the writing	were responsible for the imaging study and ex vivo tissue assays	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
3995622	24620906	LW	2	contributed to the synthesis of the tracer|were responsible for the imaging study and ex vivo tissue assays|participated in the writing	participated in the writing	Wrote the paper	-	YES
3995622	24620906	PF	2	contributed to statistical analysis of biodistribution data	contributed to statistical analysis of biodistribution data	Analyzed the data	Formal analysis	YES
3995622	24620906	RGW	2	wrote and tested the image quantification program and performed image analyses|contributed to statistical analysis of biodistribution data|participated in the writing	wrote and tested the image quantification program and performed image analyses	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Software|Visualization|Writing - Original Draft	YES
3995622	24620906	RGW	2	wrote and tested the image quantification program and performed image analyses|contributed to statistical analysis of biodistribution data|participated in the writing	contributed to statistical analysis of biodistribution data	Analyzed the data	Formal analysis	YES
3995622	24620906	RGW	2	wrote and tested the image quantification program and performed image analyses|contributed to statistical analysis of biodistribution data|participated in the writing	participated in the writing	Wrote the paper	-	YES
3995622	24620906	TDR	2	supervised and coordinated the study and manuscript preparation|participated in the writing	supervised and coordinated the study and manuscript preparation	Wrote the paper	Project administration|Supervision|Writing - Original Draft	YES
3995622	24620906	TDR	2	supervised and coordinated the study and manuscript preparation|participated in the writing	participated in the writing	Wrote the paper	-	YES
3995622	24620906	YD	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5640791	29062320	EH	2	supervised mt and provided substantial contributions to the conception and writing of the paper	supervised mt and provided substantial contributions to the conception and writing of the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Supervision|Writing - Original Draft	YES
5640791	29062320	MT	2	collected all data required for the research, developed the current scale and was the main author of the paper	collected all data required for the research, developed the current scale and was the main author of the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6055129	30033559	All authors	2	reviewed and contributed to the final manuscript and have read and approved the final version	reviewed and contributed to the final manuscript and have read and approved the final version	Wrote the paper	Writing - Review & Editing	YES
6055129	30033559	CK	2	collected the data	collected the data	Performed the experiments	Investigation	YES
6055129	30033559	CL	2	developed the cohort study	developed the cohort study	-	-	NO
6055129	30033559	CM	2	developed the cohort study|developed the costing study design	developed the cohort study	-	-	NO
6055129	30033559	CM	2	developed the cohort study|developed the costing study design	developed the costing study design	Conceived and designed the experiments	Methodology	YES
6055129	30033559	CS	2	developed the costing study design|developed the cost-effectiveness analysis|produced the results and were the lead writers of the manuscript	developed the costing study design	Conceived and designed the experiments	Methodology	YES
6055129	30033559	CS	2	developed the costing study design|developed the cost-effectiveness analysis|produced the results and were the lead writers of the manuscript	developed the cost-effectiveness analysis	-	-	NO
6055129	30033559	CS	2	developed the costing study design|developed the cost-effectiveness analysis|produced the results and were the lead writers of the manuscript	produced the results and were the lead writers of the manuscript	Wrote the paper	Writing - Original Draft	YES
6055129	30033559	DG	2	developed the costing study design	developed the costing study design	Conceived and designed the experiments	Methodology	YES
6055129	30033559	DW	2	developed the cost-effectiveness analysis	developed the cost-effectiveness analysis	-	-	NO
6055129	30033559	MM	2	developed the cohort study|developed the costing study design	developed the cohort study	-	-	NO
6055129	30033559	MM	2	developed the cohort study|developed the costing study design	developed the costing study design	Conceived and designed the experiments	Methodology	YES
6055129	30033559	PM	2	collected the data	collected the data	Performed the experiments	Investigation	YES
6055129	30033559	PP	2	developed the cohort study	developed the cohort study	-	-	NO
6055129	30033559	PT	2	collected the data	collected the data	Performed the experiments	Investigation	YES
6055129	30033559	PV	2	collected the data	collected the data	Performed the experiments	Investigation	YES
6055129	30033559	RS	2	developed the cost-effectiveness analysis|produced the results and were the lead writers of the manuscript	developed the cost-effectiveness analysis	-	-	NO
6055129	30033559	RS	2	developed the cost-effectiveness analysis|produced the results and were the lead writers of the manuscript	produced the results and were the lead writers of the manuscript	Wrote the paper	Writing - Original Draft	YES
6055129	30033559	TK	2	collected the data	collected the data	Performed the experiments	Investigation	YES
1784069	17285147	MR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1784069	17285147	MR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1784069	17285147	MR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1784069	17285147	MR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1784069	17285147	RS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1784069	17285147	RS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1784069	17285147	RS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1784069	17285147	RS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4015168	24602403	FK	2	designed the study, carried out the experiments and wrote the manuscript	designed the study, carried out the experiments and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
4015168	24602403	GEM	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4015168	24602403	JM	2	carried out experiments and revised the manuscript	carried out experiments and revised the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4015168	24602403	JW	2	carried out biodistribution and protein labelling experiments	carried out biodistribution and protein labelling experiments	Performed the experiments	Investigation	YES
4015168	24602403	PJB	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5460432	28583077	AG	2	designed the study|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5460432	28583077	AG	2	designed the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5460432	28583077	BC	2	conducted the experiments, performed the molecular biology studies and the statistical and microarray analyses|wrote the manuscript	conducted the experiments, performed the molecular biology studies and the statistical and microarray analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5460432	28583077	BC	2	conducted the experiments, performed the molecular biology studies and the statistical and microarray analyses|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5460432	28583077	MB	2	designed the study|conducted the experiments, performed the molecular biology studies and the statistical and microarray analyses|drafted the initial manuscript|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5460432	28583077	MB	2	designed the study|conducted the experiments, performed the molecular biology studies and the statistical and microarray analyses|drafted the initial manuscript|wrote the manuscript	conducted the experiments, performed the molecular biology studies and the statistical and microarray analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5460432	28583077	MB	2	designed the study|conducted the experiments, performed the molecular biology studies and the statistical and microarray analyses|drafted the initial manuscript|wrote the manuscript	drafted the initial manuscript	Wrote the paper	Writing - Original Draft	YES
5460432	28583077	MB	2	designed the study|conducted the experiments, performed the molecular biology studies and the statistical and microarray analyses|drafted the initial manuscript|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5460432	28583077	PM	2	conducted the experiments, performed the molecular biology studies and the statistical and microarray analyses|wrote the manuscript	conducted the experiments, performed the molecular biology studies and the statistical and microarray analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5460432	28583077	PM	2	conducted the experiments, performed the molecular biology studies and the statistical and microarray analyses|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5460432	28583077	SZ	2	designed the study|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5460432	28583077	SZ	2	designed the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4409365	25909361	AG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409365	25909361	AG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409365	25909361	AG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409365	25909361	AMBG	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409365	25909361	AP	PLoS5	Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409365	25909361	AP	PLoS5	Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409365	25909361	AS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4409365	25909361	AS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409365	25909361	BS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409365	25909361	CB	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409365	25909361	CM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409365	25909361	EG	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409365	25909361	Florencia Garcia	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409365	25909361	Francesc Garcia	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4409365	25909361	Francesc Garcia	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409365	25909361	J. Bargay	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409365	25909361	J. Besalduch	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409365	25909361	JB	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409365	25909361	JG	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409365	25909361	JMS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409365	25909361	JV	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409365	25909361	LB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409365	25909361	LB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409365	25909361	LB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409365	25909361	LB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409365	25909361	LG	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409365	25909361	MF	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409365	25909361	MS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409365	25909361	RDC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409365	25909361	RR	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1784070	17299591	AE	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1784070	17299591	CV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1784070	17299591	CV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1784070	17299591	CV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1784070	17299591	CV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1784070	17299591	DF	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1784070	17299591	DF	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1784070	17299591	EF	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1784070	17299591	FA	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1784070	17299591	FA	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1784070	17299591	GP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1784070	17299591	IC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1784070	17299591	IC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1784070	17299591	IC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1784070	17299591	JP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1784070	17299591	JP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1784070	17299591	JP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1784070	17299591	JS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1784070	17299591	MC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
6055130	30033558	CD	PLoS52	analysed the data|assisted in drafting the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
6055130	30033558	CD	PLoS52	analysed the data|assisted in drafting the manuscript	assisted in drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
6055130	30033558	EF	PLoS52	analysed the data|wrote the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
6055130	30033558	EF	PLoS52	analysed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6055130	30033558	FMC	PLoS52	conceived and designed the experiment|assisted in drafting the manuscript	conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
6055130	30033558	FMC	PLoS52	conceived and designed the experiment|assisted in drafting the manuscript	assisted in drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
6055130	30033558	JB	PLoS52	analysed the data|assisted in drafting the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
6055130	30033558	JB	PLoS52	analysed the data|assisted in drafting the manuscript	assisted in drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
6055130	30033558	JD	PLoS52	conceived and designed the experiment	conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
6055130	30033558	JRH	PLoS52	analysed the data|assisted in drafting the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
6055130	30033558	JRH	PLoS52	analysed the data|assisted in drafting the manuscript	assisted in drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
6055130	30033558	SM	PLoS52	conceived and designed the experiment|conceived and designed the experiment|analysed the data	conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
6055130	30033558	SM	PLoS52	conceived and designed the experiment|conceived and designed the experiment|analysed the data	conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
6055130	30033558	SM	PLoS52	conceived and designed the experiment|conceived and designed the experiment|analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
6055130	30033558	TNM	PLoS52	analysed the data|wrote the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
6055130	30033558	TNM	PLoS52	analysed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6055130	30033558	XA	PLoS52	analysed the data|assisted in drafting the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
6055130	30033558	XA	PLoS52	analysed the data|assisted in drafting the manuscript	assisted in drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
4015829	24606843	AB	2	contributed equally to this work and are joint first authors|carried out the protein radiolabelling, kit formulation, challenge assays, and drafted the manuscript	contributed equally to this work and are joint first authors	-	-	NO
4015829	24606843	AB	2	contributed equally to this work and are joint first authors|carried out the protein radiolabelling, kit formulation, challenge assays, and drafted the manuscript	carried out the protein radiolabelling, kit formulation, challenge assays, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
4015829	24606843	FK	2	contributed to production and purification of proteins	contributed to production and purification of proteins	Performed the experiments	Investigation	YES
4015829	24606843	GM	2	conceived of the study, participated in the design of the study and helped to draft the manuscript	conceived of the study, participated in the design of the study and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
4015829	24606843	JW	2	contributed equally to this work and are joint first authors|carried out protein radiolabelling, kit formulation, and drafted the manuscript	contributed equally to this work and are joint first authors	-	-	NO
4015829	24606843	JW	2	contributed equally to this work and are joint first authors|carried out protein radiolabelling, kit formulation, and drafted the manuscript	carried out protein radiolabelling, kit formulation, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
4015829	24606843	PB	2	conceived of the study, participated in the design of the study and helped to draft the manuscript	conceived of the study, participated in the design of the study and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
4015829	24606843	RT	2	contributed to production and purification of proteins	contributed to production and purification of proteins	Performed the experiments	Investigation	YES
4015829	24606843	TLC	2	quality control	quality control	Performed the experiments	Validation	YES
5641326	29067032	AL	2	led the design of the experimental trial, the management of the trial cultivation, and the collection of the agronomical data at harvest	led the design of the experimental trial, the management of the trial cultivation, and the collection of the agronomical data at harvest	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Data curation|Investigation|Methodology|Project administration	YES
5641326	29067032	All authors	2	have revised the work for intellectual content and have contributed to and approved the final content	have revised the work for intellectual content and have contributed to and approved the final content	Wrote the paper	Writing - Review & Editing	YES
5641326	29067032	JA	2	contributed to the majority of the critical revision of the manuscript text|all contributed significantly to the field and uav data acquisition, data processing, and experimental data interpretation	contributed to the majority of the critical revision of the manuscript text	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5641326	29067032	JA	2	contributed to the majority of the critical revision of the manuscript text|all contributed significantly to the field and uav data acquisition, data processing, and experimental data interpretation	all contributed significantly to the field and uav data acquisition, data processing, and experimental data interpretation	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Formal analysis|Investigation|Resources	YES
5641326	29067032	JM	2	led the design of the experimental trial, the management of the trial cultivation, and the collection of the agronomical data at harvest	led the design of the experimental trial, the management of the trial cultivation, and the collection of the agronomical data at harvest	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Data curation|Investigation|Methodology|Project administration	YES
5641326	29067032	MS	2	all contributed significantly to the field and uav data acquisition, data processing, and experimental data interpretation	all contributed significantly to the field and uav data acquisition, data processing, and experimental data interpretation	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Formal analysis|Investigation|Resources	YES
5641326	29067032	OV	2	all contributed significantly to the field and uav data acquisition, data processing, and experimental data interpretation	all contributed significantly to the field and uav data acquisition, data processing, and experimental data interpretation	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Formal analysis|Investigation|Resources	YES
5641326	29067032	RV	2	led the statistical analyses and figure preparation|contributed to the majority of the critical revision of the manuscript text|all contributed significantly to the field and uav data acquisition, data processing, and experimental data interpretation	led the statistical analyses and figure preparation	Analyzed the data	Formal analysis|Visualization	YES
5641326	29067032	RV	2	led the statistical analyses and figure preparation|contributed to the majority of the critical revision of the manuscript text|all contributed significantly to the field and uav data acquisition, data processing, and experimental data interpretation	contributed to the majority of the critical revision of the manuscript text	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5641326	29067032	RV	2	led the statistical analyses and figure preparation|contributed to the majority of the critical revision of the manuscript text|all contributed significantly to the field and uav data acquisition, data processing, and experimental data interpretation	all contributed significantly to the field and uav data acquisition, data processing, and experimental data interpretation	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Formal analysis|Investigation|Resources	YES
5641326	29067032	SCK	2	contributed to the majority of the critical revision of the manuscript text|all contributed significantly to the field and uav data acquisition, data processing, and experimental data interpretation	contributed to the majority of the critical revision of the manuscript text	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5641326	29067032	SCK	2	contributed to the majority of the critical revision of the manuscript text|all contributed significantly to the field and uav data acquisition, data processing, and experimental data interpretation	all contributed significantly to the field and uav data acquisition, data processing, and experimental data interpretation	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Formal analysis|Investigation|Resources	YES
5641326	29067032	SK	2	contributed to the majority of the critical revision of the manuscript text|all contributed significantly to the field and uav data acquisition, data processing, and experimental data interpretation|led the design of the experimental trial, the management of the trial cultivation, and the collection of the agronomical data at harvest	contributed to the majority of the critical revision of the manuscript text	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5641326	29067032	SK	2	contributed to the majority of the critical revision of the manuscript text|all contributed significantly to the field and uav data acquisition, data processing, and experimental data interpretation|led the design of the experimental trial, the management of the trial cultivation, and the collection of the agronomical data at harvest	all contributed significantly to the field and uav data acquisition, data processing, and experimental data interpretation	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Formal analysis|Investigation|Resources	YES
5641326	29067032	SK	2	contributed to the majority of the critical revision of the manuscript text|all contributed significantly to the field and uav data acquisition, data processing, and experimental data interpretation|led the design of the experimental trial, the management of the trial cultivation, and the collection of the agronomical data at harvest	led the design of the experimental trial, the management of the trial cultivation, and the collection of the agronomical data at harvest	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Data curation|Investigation|Methodology|Project administration	YES
5460460	28583072	BRS	2	study conception, experimental design, data analysis and manuscript production	study conception, experimental design, data analysis and manuscript production	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
5460460	28583072	JK	2	qrt pcr experimental design and data analysis, editing of manuscript	qrt pcr experimental design and data analysis, editing of manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Review & Editing	YES
5460460	28583072	JT	2	bioinformatic analysis of microarray and genomic data, figure production, manuscript editing	bioinformatic analysis of microarray and genomic data, figure production, manuscript editing	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Visualization|Writing - Review & Editing	YES
5460460	28583072	LL	2	sl experimental design, generation of experimental data, data analysis and manuscript production	sl experimental design, generation of experimental data, data analysis and manuscript production	Conceived and designed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5460460	28583072	WW	2	bioinformatic analysis of microarray and genomic data, figure production, manuscript editing	bioinformatic analysis of microarray and genomic data, figure production, manuscript editing	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Visualization|Writing - Review & Editing	YES
5460460	28583072	ZD	2	qrt pcr experimental design and data analysis, editing of manuscript	qrt pcr experimental design and data analysis, editing of manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Review & Editing	YES
3766572	24058286	Dong Chang	2	are cofirst authors for equal contribution to the present study	are cofirst authors for equal contribution to the present study	-	-	NO
3766572	24058286	Kejing Wang	2	are cofirst authors for equal contribution to the present study	are cofirst authors for equal contribution to the present study	-	-	NO
3766572	24058286	Zhenliang Chu	2	are cofirst authors for equal contribution to the present study	are cofirst authors for equal contribution to the present study	-	-	NO
1784071	17285144	AH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1784071	17285144	AH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1784071	17285144	AH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1784071	17285144	AH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1784071	17285144	AH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1784071	17285144	FG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1784071	17285144	FG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1784071	17285144	FG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1784071	17285144	FG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1784071	17285144	FG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1784071	17285144	SZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1784071	17285144	SZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1784071	17285144	SZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1784071	17285144	XW	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1784071	17285144	XW	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1784071	17285144	XW	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1784071	17285144	XW	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4029781	24308868	AA	2	performed the statistical analysis and critically revised the manuscript	performed the statistical analysis and critically revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4029781	24308868	AAL	2	were involved in the acquisition and interpretation of the pet studies, and critically revised the manuscript	were involved in the acquisition and interpretation of the pet studies, and critically revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4029781	24308868	BNMB	2	were involved in the acquisition and interpretation of the pet studies, and critically revised the manuscript	were involved in the acquisition and interpretation of the pet studies, and critically revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4029781	24308868	CJMK	2	participated in the design of the study and critically revised the manuscript	participated in the design of the study and critically revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
4029781	24308868	GJB	2	participated in the design of the study and critically revised the manuscript	participated in the design of the study and critically revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
4029781	24308868	JPB	2	were involved in the acquisition and interpretation of the pet studies, and critically revised the manuscript	were involved in the acquisition and interpretation of the pet studies, and critically revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4029781	24308868	LJK	2	participated in the design of the study and critically revised the manuscript	participated in the design of the study and critically revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
4029781	24308868	RB	2	were involved in the acquisition and interpretation of the pet studies, and critically revised the manuscript	were involved in the acquisition and interpretation of the pet studies, and critically revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4029781	24308868	SP	2	participated in the design of the study, performed the statistical analysis and drafted the manuscript	participated in the design of the study, performed the statistical analysis and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
6055131	30033604	All authors	2	contributed to data interpretation, writing the manuscript and approved the final version	contributed to data interpretation, writing the manuscript and approved the final version	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6055131	30033604	BL	2	collected or contributed data for the modelling	collected or contributed data for the modelling	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources	YES
6055131	30033604	CL	2	collected or contributed data for the modelling	collected or contributed data for the modelling	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources	YES
6055131	30033604	CN	2	collected or contributed data for the modelling	collected or contributed data for the modelling	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources	YES
6055131	30033604	CT	2	collected or contributed data for the modelling	collected or contributed data for the modelling	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources	YES
6055131	30033604	DD	2	collected or contributed data for the modelling	collected or contributed data for the modelling	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources	YES
6055131	30033604	FD	2	collected or contributed data for the modelling	collected or contributed data for the modelling	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources	YES
6055131	30033604	JW	2	undertook data analyses for parameterizing and calibrating the model	undertook data analyses for parameterizing and calibrating the model	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
6055131	30033604	KC	2	collected or contributed data for the modelling	collected or contributed data for the modelling	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources	YES
6055131	30033604	LD	2	undertook data analyses for parameterizing and calibrating the model	undertook data analyses for parameterizing and calibrating the model	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
6055131	30033604	MCB	2	conceptualized the study	conceptualized the study	Conceived and designed the experiments	Conceptualization	YES
6055131	30033604	NLD	2	collected or contributed data for the modelling	collected or contributed data for the modelling	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources	YES
6055131	30033604	PAND	2	collected or contributed data for the modelling	collected or contributed data for the modelling	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources	YES
6055131	30033604	PV	2	conceptualized the study|supervised the model analyses	conceptualized the study	Conceived and designed the experiments	Conceptualization	YES
6055131	30033604	PV	2	conceptualized the study|supervised the model analyses	supervised the model analyses	Performed the experiments|Analyzed the data	Formal analysis|Methodology|Supervision	YES
6055131	30033604	RSMM	2	collected or contributed data for the modelling	collected or contributed data for the modelling	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources	YES
6055131	30033604	SB	2	conceptualized the study|collected or contributed data for the modelling	conceptualized the study	Conceived and designed the experiments	Conceptualization	YES
6055131	30033604	SB	2	conceptualized the study|collected or contributed data for the modelling	collected or contributed data for the modelling	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources	YES
6055131	30033604	SM	2	conceptualized the study	conceptualized the study	Conceived and designed the experiments	Conceptualization	YES
6055131	30033604	SS	2	conceptualized the study|collected or contributed data for the modelling	conceptualized the study	Conceived and designed the experiments	Conceptualization	YES
6055131	30033604	SS	2	conceptualized the study|collected or contributed data for the modelling	collected or contributed data for the modelling	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources	YES
6055131	30033604	ST	2	collected or contributed data for the modelling	collected or contributed data for the modelling	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources	YES
5641357	29067028	All authors	2	contributed to the revision of the manuscript	contributed to the revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5641357	29067028	TH	2	wrote the draft together and contribute equally to this work	wrote the draft together and contribute equally to this work	Wrote the paper	Writing - Original Draft	YES
5641357	29067028	XY	2	draw the model	draw the model	Performed the experiments	Methodology	YES
5641357	29067028	YH	2	conceived the review and supervised the whole work	conceived the review and supervised the whole work	Conceived and designed the experiments	Conceptualization|Supervision	YES
5641357	29067028	ZH	2	wrote the draft together and contribute equally to this work	wrote the draft together and contribute equally to this work	Wrote the paper	Writing - Original Draft	YES
4409366	25909952	AOO	PLoS5	Critically evaluated the manuscript and provided scientific input	Critically evaluated the manuscript and provided scientific input	-	-	NO
4409366	25909952	DSR	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409366	25909952	DSR	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409366	25909952	EAD	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409366	25909952	HIF	PLoS5	Critically evaluated the manuscript and provided scientific input	Critically evaluated the manuscript and provided scientific input	-	-	NO
4409366	25909952	IRB	PLoS5	Critically evaluated the manuscript and provided scientific input	Critically evaluated the manuscript and provided scientific input	-	-	NO
4409366	25909952	JCF	PLoS5	Critically evaluated the manuscript and provided scientific input	Critically evaluated the manuscript and provided scientific input	-	-	NO
4409366	25909952	JG	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409366	25909952	JG	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409366	25909952	JWK	PLoS5	Critically evaluated the manuscript and provided scientific input	Critically evaluated the manuscript and provided scientific input	-	-	NO
4409366	25909952	MGK	PLoS5	Critically evaluated the manuscript and provided scientific input	Critically evaluated the manuscript and provided scientific input	-	-	NO
4409366	25909952	MMJ	PLoS5	Critically evaluated the manuscript and provided scientific input	Critically evaluated the manuscript and provided scientific input	-	-	NO
4409366	25909952	MPR	PLoS5	Critically evaluated the manuscript and provided scientific input	Critically evaluated the manuscript and provided scientific input	-	-	NO
4409366	25909952	MW	PLoS5	Critically evaluated the manuscript and provided scientific input	Critically evaluated the manuscript and provided scientific input	-	-	NO
4409366	25909952	RRT	PLoS5	Critically evaluated the manuscript and provided scientific input	Critically evaluated the manuscript and provided scientific input	-	-	NO
4409366	25909952	SER	PLoS5	Critically evaluated the manuscript and provided scientific input	Critically evaluated the manuscript and provided scientific input	-	-	NO
4409366	25909952	SSP	PLoS5	Critically evaluated the manuscript and provided scientific input	Critically evaluated the manuscript and provided scientific input	-	-	NO
5460472	28583088	BZ	4	Study was designed by|Data was analyzed by|Manuscript was written by	Study was designed by	Conceived and designed the experiments	Methodology	YES
5460472	28583088	BZ	4	Study was designed by|Data was analyzed by|Manuscript was written by	Data was analyzed by	Analyzed the data	Formal analysis	YES
5460472	28583088	BZ	4	Study was designed by|Data was analyzed by|Manuscript was written by	Manuscript was written by	Wrote the paper	Writing - Original Draft	YES
5460472	28583088	JF	4	Data was analyzed by|Manuscript was written by	Data was analyzed by	Analyzed the data	Formal analysis	YES
5460472	28583088	JF	4	Data was analyzed by|Manuscript was written by	Manuscript was written by	Wrote the paper	Writing - Original Draft	YES
5460472	28583088	JG	4	Experiment was performed by	Experiment was performed by	Performed the experiments	Investigation	YES
5460472	28583088	KK	4	Experiment was performed by	Experiment was performed by	Performed the experiments	Investigation	YES
5460472	28583088	PM	4	Study was designed by	Study was designed by	Conceived and designed the experiments	Methodology	YES
5460472	28583088	SS	4	Experiment was performed by	Experiment was performed by	Performed the experiments	Investigation	YES
5460472	28583088	TW	4	Study was designed by|Manuscript was written by	Study was designed by	Conceived and designed the experiments	Methodology	YES
5460472	28583088	TW	4	Study was designed by|Manuscript was written by	Manuscript was written by	Wrote the paper	Writing - Original Draft	YES
5460472	28583088	XX	4	Experiment was performed by	Experiment was performed by	Performed the experiments	Investigation	YES
1784073	17285148	CM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1784073	17285148	CM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1784073	17285148	CM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1784073	17285148	MV	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1784073	17285148	MV	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1784073	17285148	MV	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4052880	24949282	BP	2	drafted the manuscript, substantially contributed to the conception and design of the study, and acquired, analysed and interpreted the data	drafted the manuscript, substantially contributed to the conception and design of the study, and acquired, analysed and interpreted the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
4052880	24949282	DH	2	substantially contributed to the conception and design of the study and acquired clinical data	substantially contributed to the conception and design of the study and acquired clinical data	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceptualization|Investigation|Methodology|Resources	YES
4052880	24949282	LWV	2	substantially contributed to the conception and design of the study and revised the manuscript critically for important intellectual content	substantially contributed to the conception and design of the study and revised the manuscript critically for important intellectual content	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
4052880	24949282	MS	2	approved the final manuscript for submission and publication and revised the article critically for important intellectual content	approved the final manuscript for submission and publication and revised the article critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4052880	24949282	MVP	2	drafted and revised the manuscript critically for important intellectual content	drafted and revised the manuscript critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4052880	24949282	OB	2	substantially contributed to the conception and design of the study and acquired clinical data	substantially contributed to the conception and design of the study and acquired clinical data	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceptualization|Investigation|Methodology|Resources	YES
4052880	24949282	RVO	2	approved the final manuscript for submission and publication and revised the article critically for important intellectual content	approved the final manuscript for submission and publication and revised the article critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4061749	24401181	ADJ	2	participated in the study design, image analysis, and data interpretation and drafted the manuscript	participated in the study design, image analysis, and data interpretation and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Visualization|Writing - Original Draft	YES
4061749	24401181	APC	2	was responsible for the administrative and material support, data interpretation and critical review of the manuscript	was responsible for the administrative and material support, data interpretation and critical review of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Project administration|Writing - Review & Editing	YES
4061749	24401181	DMS	2	supervised the study, provided administrative or material support and participated in the critical review	supervised the study, provided administrative or material support and participated in the critical review	Contributed reagents/materials/analysis tools	Project administration|Resources|Supervision	YES
4061749	24401181	LA	2	carried out the data acquisition and participated in the scientific review	carried out the data acquisition and participated in the scientific review	Performed the experiments	Investigation	YES
4061749	24401181	MAM	2	participated in the data interpretation and critical review of the manuscript	participated in the data interpretation and critical review of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4061749	24401181	MGS	2	performed the dosimetry analysis	performed the dosimetry analysis	Performed the experiments	Investigation	YES
4061749	24401181	MJP	2	was responsible for the study concept and design, data interpretation and review of the manuscript	was responsible for the study concept and design, data interpretation and review of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Review & Editing	YES
1788933	17299594	HK	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1788933	17299594	HL	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1788933	17299594	IO	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1788933	17299594	KL	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1788933	17299594	PJ	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1788933	17299594	PJ	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5460480	28583065	ARZ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5460480	28583065	DAB	PLoS52	invented the nope method|worked on the manuscript	invented the nope method	Performed the experiments	-	YES
5460480	28583065	DAB	PLoS52	invented the nope method|worked on the manuscript	worked on the manuscript	Performed the experiments	-	YES
5460480	28583065	DAS	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5460480	28583065	DMC	PLoS52	invented the nope method|supervised the work|worked on the manuscript	invented the nope method	Performed the experiments	-	YES
5460480	28583065	DMC	PLoS52	invented the nope method|supervised the work|worked on the manuscript	supervised the work	-	Supervision	YES
5460480	28583065	DMC	PLoS52	invented the nope method|supervised the work|worked on the manuscript	worked on the manuscript	Performed the experiments	-	YES
5460480	28583065	IAS	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5460480	28583065	MAT	PLoS52	invented the nope method|performed the experiments|worked on the manuscript	invented the nope method	Performed the experiments	-	YES
5460480	28583065	MAT	PLoS52	invented the nope method|performed the experiments|worked on the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5460480	28583065	MAT	PLoS52	invented the nope method|performed the experiments|worked on the manuscript	worked on the manuscript	Performed the experiments	-	YES
5460480	28583065	MS	PLoS52	performed data analysis	performed data analysis	Analyzed the data	Formal analysis	YES
5460480	28583065	OIZ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5460480	28583065	SL	PLoS52	supervised the work	supervised the work	-	Supervision	YES
5641359	29067031	AC	2	conceived and designed the research|carried the experimental work, collected and prepared the data|conducted statistical analyses|interpreted the data and wrote the paper	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5641359	29067031	AC	2	conceived and designed the research|carried the experimental work, collected and prepared the data|conducted statistical analyses|interpreted the data and wrote the paper	carried the experimental work, collected and prepared the data	Performed the experiments	Investigation	YES
5641359	29067031	AC	2	conceived and designed the research|carried the experimental work, collected and prepared the data|conducted statistical analyses|interpreted the data and wrote the paper	conducted statistical analyses	Analyzed the data	Formal analysis	YES
5641359	29067031	AC	2	conceived and designed the research|carried the experimental work, collected and prepared the data|conducted statistical analyses|interpreted the data and wrote the paper	interpreted the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5641359	29067031	HA	2	carried the experimental work, collected and prepared the data	carried the experimental work, collected and prepared the data	Performed the experiments	Investigation	YES
5641359	29067031	HR	2	interpreted the data and wrote the paper	interpreted the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5641359	29067031	JB	2	interpreted the data and wrote the paper	interpreted the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5641359	29067031	M-DP	2	carried the experimental work, collected and prepared the data	carried the experimental work, collected and prepared the data	Performed the experiments	Investigation	YES
5641359	29067031	NL	2	conceived and designed the research|directed the work|interpreted the data and wrote the paper	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5641359	29067031	NL	2	conceived and designed the research|directed the work|interpreted the data and wrote the paper	directed the work	-	Supervision	YES
5641359	29067031	NL	2	conceived and designed the research|directed the work|interpreted the data and wrote the paper	interpreted the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5641359	29067031	OD	2	carried the experimental work, collected and prepared the data	carried the experimental work, collected and prepared the data	Performed the experiments	Investigation	YES
5641359	29067031	SC	2	carried the experimental work, collected and prepared the data	carried the experimental work, collected and prepared the data	Performed the experiments	Investigation	YES
5641359	29067031	SD-M	2	conceived and designed the research|directed the work|interpreted the data and wrote the paper	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5641359	29067031	SD-M	2	conceived and designed the research|directed the work|interpreted the data and wrote the paper	directed the work	-	Supervision	YES
5641359	29067031	SD-M	2	conceived and designed the research|directed the work|interpreted the data and wrote the paper	interpreted the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5641359	29067031	SS	2	conceived and designed the research|directed the work|interpreted the data and wrote the paper	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5641359	29067031	SS	2	conceived and designed the research|directed the work|interpreted the data and wrote the paper	directed the work	-	Supervision	YES
5641359	29067031	SS	2	conceived and designed the research|directed the work|interpreted the data and wrote the paper	interpreted the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4424489	25939626	A.B.	2	worked on the identification of experimental problems	worked on the identification of experimental problems	Performed the experiments	Investigation	YES
4424489	25939626	A.J.B.	2	jointly prepared the text for this article	jointly prepared the text for this article	Wrote the paper	Writing - Original Draft	YES
4424489	25939626	M.B.	2	jointly prepared the text for this article	jointly prepared the text for this article	Wrote the paper	Writing - Original Draft	YES
4424489	25939626	M.D.	2	were the main designers of the theoretical pipeline presented here	were the main designers of the theoretical pipeline presented here	Conceived and designed the experiments	Formal analysis	YES
4424489	25939626	R.A.	2	being initial testers and plugin developers|were the main designers of the theoretical pipeline presented here	being initial testers and plugin developers	-	-	NO
4424489	25939626	R.A.	2	being initial testers and plugin developers|were the main designers of the theoretical pipeline presented here	were the main designers of the theoretical pipeline presented here	Conceived and designed the experiments	Formal analysis	YES
4424489	25939626	R.C.A.	2	jointly prepared the text for this article	jointly prepared the text for this article	Wrote the paper	Writing - Original Draft	YES
4424489	25939626	S.P.	2	being initial testers and plugin developers|worked on the identification of experimental problems	being initial testers and plugin developers	-	-	NO
4424489	25939626	S.P.	2	being initial testers and plugin developers|worked on the identification of experimental problems	worked on the identification of experimental problems	Performed the experiments	Investigation	YES
4424489	25939626	S.W.T.P.	2	jointly prepared the text for this article	jointly prepared the text for this article	Wrote the paper	Writing - Original Draft	YES
4070025	24995151	AB	2	analyzed data and contributed to the manuscript writing	analyzed data and contributed to the manuscript writing	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4070025	24995151	AC	2	collected and analyzed data	collected and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4070025	24995151	AS	2	designed the study, interpreted the data, and revised the manuscript critically	designed the study, interpreted the data, and revised the manuscript critically	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
4070025	24995151	All authors	2	have met the criteria for authorship	have met the criteria for authorship	-	-	NO
4070025	24995151	CM	2	analyzed the data and revised the manuscript	analyzed the data and revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4070025	24995151	DM	2	collected and interpreted data	collected and interpreted data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4070025	24995151	FL	2	analyzed the data and revised the manuscript	analyzed the data and revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4070025	24995151	GC	2	collected, analyzed, and interpreted the data, and wrote the paper	collected, analyzed, and interpreted the data, and wrote the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4070025	24995151	HG	2	interpreted the data and revised the manuscript critically	interpreted the data and revised the manuscript critically	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4070025	24995151	JH	2	analyzed data and contributed to the manuscript writing	analyzed data and contributed to the manuscript writing	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4070025	24995151	MC	2	collected, analyzed, and interpreted the data, and wrote the paper	collected, analyzed, and interpreted the data, and wrote the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4070025	24995151	ME	2	analyzed data and contributed to the manuscript writing	analyzed data and contributed to the manuscript writing	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4070025	24995151	TJ	2	collected and interpreted data	collected and interpreted data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4409367	25910248	HZC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409367	25910248	JZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409367	25910248	LYL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409367	25910248	LYL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409367	25910248	LYL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409367	25910248	LYL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409367	25910248	LYL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409367	25910248	WMY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409367	25910248	WMY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4409367	25910248	WMY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4409367	25910248	WMY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409367	25910248	XF	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409367	25910248	YHW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409367	25910248	YSH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409367	25910248	YW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Critically revised the manuscript for important intellectual content	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409367	25910248	YW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Critically revised the manuscript for important intellectual content	Analyzed the data	Analyzed the data	Formal analysis	YES
4409367	25910248	YW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Critically revised the manuscript for important intellectual content	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409367	25910248	YW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Critically revised the manuscript for important intellectual content	Critically revised the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4409367	25910248	ZW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409367	25910248	ZZ	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4409367	25910248	ZZ	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
6055132	30033673	GM	2	all contributed to the preparation of the first draft	all contributed to the preparation of the first draft	Wrote the paper	Writing - Original Draft	YES
6055132	30033673	RCW	2	all contributed to the preparation of the first draft	all contributed to the preparation of the first draft	Wrote the paper	Writing - Original Draft	YES
6055132	30033673	RW	2	all contributed to the preparation of the first draft	all contributed to the preparation of the first draft	Wrote the paper	Writing - Original Draft	YES
6055132	30033673	TB	2	all contributed to the preparation of the first draft	all contributed to the preparation of the first draft	Wrote the paper	Writing - Original Draft	YES
1789077	17299595	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1789077	17299595	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1789077	17299595	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1789077	17299595	JH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1789077	17299595	JP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1789077	17299595	KF	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1789077	17299595	MF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1789077	17299595	MF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1789077	17299595	MF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1789077	17299595	RV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1789077	17299595	RV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1789077	17299595	RV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1789077	17299595	RV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4070081	24995150	CT	2	scanning, and data interpretation	scanning, and data interpretation	Analyzed the data	Formal analysis	YES
4070081	24995150	HCG	2	performed the quantification of spect data	performed the quantification of spect data	Performed the experiments	Investigation	YES
4070081	24995150	MM	2	participated in its design and coordination and helped draft the manuscript	participated in its design and coordination and helped draft the manuscript	Conceived and designed the experiments|Wrote the paper	Project administration|Writing - Original Draft	YES
4070081	24995150	MdJ	2	participated in its design and coordination and helped draft the manuscript	participated in its design and coordination and helped draft the manuscript	Conceived and designed the experiments|Wrote the paper	Project administration|Writing - Original Draft	YES
4070081	24995150	SEP	2	performed part of the animal experiments, participated in the design of the studies, and wrote the manuscript	performed part of the animal experiments, participated in the design of the studies, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
4070081	24995150	SMB	2	performed part of the animal experiments, participated in the design of the studies, and wrote the manuscript	performed part of the animal experiments, participated in the design of the studies, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
4409368	25909640	AE	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409368	25909640	AE	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409368	25909640	AOM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409368	25909640	AOM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409368	25909640	AOM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409368	25909640	AOM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409368	25909640	AOM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409368	25909640	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409368	25909640	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409368	25909640	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409368	25909640	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409368	25909640	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409368	25909640	FA	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409368	25909640	FA	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409368	25909640	GB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409368	25909640	GB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409368	25909640	GB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409368	25909640	GB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409368	25909640	GB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409368	25909640	MAA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409368	25909640	MAA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4409368	25909640	MAA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4409368	25909640	MAA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409368	25909640	MHM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409368	25909640	MHM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409368	25909640	MHM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409368	25909640	SA	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409368	25909640	SA	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409368	25909640	SA	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409368	25909640	SA	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5460488	28583075	CCB	2	generated the gene expression datasets|wrote the manuscript	generated the gene expression datasets	Performed the experiments	Investigation	YES
5460488	28583075	CCB	2	generated the gene expression datasets|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5460488	28583075	GAW	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5460488	28583075	RH	2	performed the rank bi-serial analyses|wrote the manuscript	performed the rank bi-serial analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5460488	28583075	RH	2	performed the rank bi-serial analyses|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5460488	28583075	WN	2	generated the gene expression datasets	generated the gene expression datasets	Performed the experiments	Investigation	YES
1789144	17299596	ID	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1789144	17299596	JK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1789144	17299596	JK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1789144	17299596	JK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1789144	17299596	JW	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1789144	17299596	NF	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1789144	17299596	NF	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1789144	17299596	NF	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1789144	17299596	PK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1789144	17299596	PK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1789144	17299596	PK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1789144	17299596	PK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1789144	17299596	RZ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1789144	17299596	RZ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1789144	17299596	RZ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1789144	17299596	SP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1789144	17299596	SP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1789144	17299596	SP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5641372	29067033	AF-N	2	conceived and supervised the work and finalized the manuscript	conceived and supervised the work and finalized the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Supervision|Writing - Review & Editing	YES
5641372	29067033	AdA	2	worked in qpcr experiments	worked in qpcr experiments	Performed the experiments	Investigation	YES
5641372	29067033	MA	2	was involved in experimental design and overall execution, as well as drafting the manuscript	was involved in experimental design and overall execution, as well as drafting the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5641372	29067033	MdA	2	helped in tissue culture assays and gene expression experiments	helped in tissue culture assays and gene expression experiments	Performed the experiments	Investigation	YES
4550748	26351640	Shiwei Zhang	2	contributed equally to this work	contributed equally to this work	-	-	NO
4550748	26351640	Xuefeng Qiu	2	contributed equally to this work	contributed equally to this work	-	-	NO
6058206	29972287	AG	2	contributed to intervention development and oversaw implementation of the intervention and contributed to the main finding interpretations and edited the manuscript	contributed to intervention development and oversaw implementation of the intervention and contributed to the main finding interpretations and edited the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
6058206	29972287	AP	2	developed the study design, raised funds for the trial and oversaw implementation of the study, interpreted study findings and wrote up the findings	developed the study design, raised funds for the trial and oversaw implementation of the study, interpreted study findings and wrote up the findings	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Funding acquisition|Investigation|Methodology|Supervision|Writing - Original Draft	YES
6058206	29972287	AS	2	oversaw implementation in the field, conducted study feedback and contributed to interpretation of finding and edited the manuscript	oversaw implementation in the field, conducted study feedback and contributed to interpretation of finding and edited the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Supervision|Writing - Review & Editing	YES
6058206	29972287	CM	2	developed the study design, raised funds for the trial and oversaw implementation of the study, interpreted study findings and wrote up the findings	developed the study design, raised funds for the trial and oversaw implementation of the study, interpreted study findings and wrote up the findings	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Funding acquisition|Investigation|Methodology|Supervision|Writing - Original Draft	YES
6058206	29972287	DP	2	contributed to intervention development and oversaw implementation of the intervention and contributed to the main finding interpretations and edited the manuscript	contributed to intervention development and oversaw implementation of the intervention and contributed to the main finding interpretations and edited the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
6058206	29972287	DR	2	contributed to intervention development and oversaw implementation of the intervention and contributed to the main finding interpretations and edited the manuscript	contributed to intervention development and oversaw implementation of the intervention and contributed to the main finding interpretations and edited the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
6058206	29972287	FXG	2	oversaw implementation in the field, conducted study feedback and contributed to interpretation of finding and edited the manuscript	oversaw implementation in the field, conducted study feedback and contributed to interpretation of finding and edited the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Supervision|Writing - Review & Editing	YES
6058206	29972287	KK	2	developed the study design, raised funds for the trial and oversaw implementation of the study, interpreted study findings and wrote up the findings	developed the study design, raised funds for the trial and oversaw implementation of the study, interpreted study findings and wrote up the findings	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Funding acquisition|Investigation|Methodology|Supervision|Writing - Original Draft	YES
6058206	29972287	RT	2	oversaw implementation in the field, conducted study feedback and contributed to interpretation of finding and edited the manuscript	oversaw implementation in the field, conducted study feedback and contributed to interpretation of finding and edited the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Supervision|Writing - Review & Editing	YES
6058206	29972287	SL	2	developed the study design, raised funds for the trial and oversaw implementation of the study, interpreted study findings and wrote up the findings	developed the study design, raised funds for the trial and oversaw implementation of the study, interpreted study findings and wrote up the findings	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Funding acquisition|Investigation|Methodology|Supervision|Writing - Original Draft	YES
6058206	29972287	SM	2	contributed to intervention development and oversaw implementation of the intervention and contributed to the main finding interpretations and edited the manuscript	contributed to intervention development and oversaw implementation of the intervention and contributed to the main finding interpretations and edited the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
6058206	29972287	ST	2	developed the study design, raised funds for the trial and oversaw implementation of the study, interpreted study findings and wrote up the findings	developed the study design, raised funds for the trial and oversaw implementation of the study, interpreted study findings and wrote up the findings	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Funding acquisition|Investigation|Methodology|Supervision|Writing - Original Draft	YES
4077623	25006544	CC	2	analysed the 60 examinations included in this study twice and took part to the final review and validation of the manuscript	analysed the 60 examinations included in this study twice and took part to the final review and validation of the manuscript	Performed the experiments|Wrote the paper	Investigation|Validation|Writing - Review & Editing	YES
4077623	25006544	CGC	2	is the second author	is the second author	-	-	NO
4077623	25006544	CL	2	brought their deep knowledge about the choline tracer and supported the literature review	brought their deep knowledge about the choline tracer and supported the literature review	-	Formal analysis	YES
4077623	25006544	CP	2	is the first author|coordinated all actions around this article	is the first author	-	-	NO
4077623	25006544	CP	2	is the first author|coordinated all actions around this article	coordinated all actions around this article	-	Project administration	YES
4077623	25006544	CT	2	examination and for their daily support during this study	examination and for their daily support during this study	Performed the experiments	Investigation	YES
4077623	25006544	HB	2	is the next to last author	is the next to last author	-	-	NO
4077623	25006544	JD	2	analysed the 60 examinations included in this study twice	analysed the 60 examinations included in this study twice	Performed the experiments	Investigation	YES
4077623	25006544	JG	2	performed the statistical calculations	performed the statistical calculations	Analyzed the data	Formal analysis	YES
4077623	25006544	JPV	2	is the last author	is the last author	-	-	NO
4077623	25006544	MDD	2	brought their deep knowledge about the choline tracer and supported the literature review	brought their deep knowledge about the choline tracer and supported the literature review	-	Formal analysis	YES
4528831	26217051	All authors	2	gave final approval for publication	gave final approval for publication	-	-	NO
4528831	26217051	C.D.	2	carried out extrusion and collected data	carried out extrusion and collected data	Performed the experiments	Investigation	YES
4528831	26217051	C.R.M.G.	2	conceived and coordinated the work	conceived and coordinated the work	Conceived and designed the experiments	Conceptualization|Project administration	YES
4528831	26217051	D.I.	2	carried out filament manufacture, additive manufacture and collected data	carried out filament manufacture, additive manufacture and collected data	Performed the experiments	Investigation	YES
4528831	26217051	F.C.	2	carried out filament production, additive manufacture and drafted the manuscript	carried out filament production, additive manufacture and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4528831	26217051	J.M.J.	2	carried out casting and collected data	carried out casting and collected data	Performed the experiments	Investigation	YES
4528831	26217051	P.S.G.	2	conceived and coordinated the work and finalized the manuscript	conceived and coordinated the work and finalized the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Project administration|Writing - Review & Editing	YES
4528831	26217051	Q.L.	2	carried out casting and collected data	carried out casting and collected data	Performed the experiments	Investigation	YES
4528831	26217051	S.S.	2	carried out superconductivity measurements	carried out superconductivity measurements	Performed the experiments	Investigation	YES
4528831	26217051	Y.W.	2	carried out spray deposition, casting, additive manufacture and collected data	carried out spray deposition, casting, additive manufacture and collected data	Performed the experiments	Investigation	YES
4409369	25909323	AC	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409369	25909323	AC	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409369	25909323	AP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409369	25909323	AP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409369	25909323	AP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409369	25909323	CS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409369	25909323	CS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409369	25909323	CS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409369	25909323	DB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409369	25909323	DB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409369	25909323	DB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409369	25909323	JR	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409369	25909323	JR	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409369	25909323	JR	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5460524	28583129	DS	2	designed the study, and supervised and complemented the writing	designed the study, and supervised and complemented the writing	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision	YES
5460524	28583129	HO	2	designed the study, and supervised and complemented the writing	designed the study, and supervised and complemented the writing	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision	YES
5460524	28583129	NS	2	gave technical support, supervised the database development, and complemented the writing	gave technical support, supervised the database development, and complemented the writing	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Software|Supervision	YES
5460524	28583129	TN	2	designed the study, analyzed the data, developed the database, and wrote the paper	designed the study, analyzed the data, developed the database, and wrote the paper	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Software|Writing - Original Draft	YES
5460524	28583129	TO	2	designed the study, and supervised and complemented the writing	designed the study, and supervised and complemented the writing	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision	YES
5641375	29067034	AV-S	2	commented on the manuscript	commented on the manuscript	-	-	NO
5641375	29067034	EL	2	performed the experiments, analyzed the data, and all authors discussed the results|wrote the manuscript	performed the experiments, analyzed the data, and all authors discussed the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5641375	29067034	EL	2	performed the experiments, analyzed the data, and all authors discussed the results|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5641375	29067034	ES	2	commented on the manuscript	commented on the manuscript	-	-	NO
5641375	29067034	RO	2	commented on the manuscript	commented on the manuscript	-	-	NO
6058263	30044059	All authors	5	participated in numerous rounds of discussions	participated in numerous rounds of discussions	-	-	NO
4409370	25909512	DI	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409370	25909512	DI	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409370	25909512	DI	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409370	25909512	JD	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409370	25909512	JD	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409370	25909512	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409370	25909512	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409370	25909512	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409370	25909512	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1789242	17299598	AR	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1789242	17299598	HY	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1789242	17299598	HY	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1789242	17299598	HY	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1789242	17299598	JK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1789242	17299598	JK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1789242	17299598	KP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1789242	17299598	KP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1789242	17299598	KP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1789242	17299598	MO	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1789242	17299598	MO	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1789242	17299598	MO	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1789242	17299598	MO	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1789242	17299598	MS	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1789242	17299598	TS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4077627	25006547	AH	2	performed dota conjugation and radiorabelling of the antibody	performed dota conjugation and radiorabelling of the antibody	Performed the experiments	Investigation	YES
4077627	25006547	HI	2	developed and evaluated the antibody	developed and evaluated the antibody	Performed the experiments	Investigation	YES
4077627	25006547	HK	2	performed dota conjugation and radiorabelling of the antibody	performed dota conjugation and radiorabelling of the antibody	Performed the experiments	Investigation	YES
4077627	25006547	KF	2	designed the study|performed the animal study and drafted the manuscript|performed pathological analysis	designed the study	Conceived and designed the experiments	Methodology	YES
4077627	25006547	KF	2	designed the study|performed the animal study and drafted the manuscript|performed pathological analysis	performed the animal study and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4077627	25006547	KF	2	designed the study|performed the animal study and drafted the manuscript|performed pathological analysis	performed pathological analysis	Performed the experiments	Investigation	YES
4077627	25006547	KK	2	designed the study|performed the animal study and drafted the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
4077627	25006547	KK	2	designed the study|performed the animal study and drafted the manuscript	performed the animal study and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4077627	25006547	KM	2	developed and evaluated the antibody	developed and evaluated the antibody	Performed the experiments	Investigation	YES
4077627	25006547	KS	2	designed the study|performed the animal study and drafted the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
4077627	25006547	KS	2	designed the study|performed the animal study and drafted the manuscript	performed the animal study and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4077627	25006547	MF	2	performed pathological analysis	performed pathological analysis	Performed the experiments	Investigation	YES
4077627	25006547	MI	2	performed pathological analysis	performed pathological analysis	Performed the experiments	Investigation	YES
4077627	25006547	OKA	2	developed and evaluated the antibody	developed and evaluated the antibody	Performed the experiments	Investigation	YES
4077627	25006547	TH	2	developed and evaluated the antibody	developed and evaluated the antibody	Performed the experiments	Investigation	YES
4077627	25006547	TK	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
4077627	25006547	TM	2	designed the study|performed the animal study and drafted the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
4077627	25006547	TM	2	designed the study|performed the animal study and drafted the manuscript	performed the animal study and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4077627	25006547	YS	2	performed dota conjugation and radiorabelling of the antibody	performed dota conjugation and radiorabelling of the antibody	Performed the experiments	Investigation	YES
6058272	30044056	All authors	2	have contributed to the preparation of the manuscript, read and approved the final draft	have contributed to the preparation of the manuscript, read and approved the final draft	Wrote the paper	Writing - Original Draft	YES
5460543	28583074	AF	2	generated the experimental data	generated the experimental data	Performed the experiments	Investigation	YES
5460543	28583074	GR	2	designed and coordinated the study|contributed to the writing of the manuscript	designed and coordinated the study	Conceived and designed the experiments	Methodology|Project administration	YES
5460543	28583074	GR	2	designed and coordinated the study|contributed to the writing of the manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5460543	28583074	JK	2	generated the experimental data	generated the experimental data	Performed the experiments	Investigation	YES
5460543	28583074	MS	2	designed and coordinated the study|contributed to the writing of the manuscript	designed and coordinated the study	Conceived and designed the experiments	Methodology|Project administration	YES
5460543	28583074	MS	2	designed and coordinated the study|contributed to the writing of the manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5460543	28583074	SvS	2	designed and coordinated the study|performed the computational analysis of the data|contributed to the writing of the manuscript	designed and coordinated the study	Conceived and designed the experiments	Methodology|Project administration	YES
5460543	28583074	SvS	2	designed and coordinated the study|performed the computational analysis of the data|contributed to the writing of the manuscript	performed the computational analysis of the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5460543	28583074	SvS	2	designed and coordinated the study|performed the computational analysis of the data|contributed to the writing of the manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5460543	28583074	VP	2	generated the experimental data	generated the experimental data	Performed the experiments	Investigation	YES
5460543	28583074	WC	2	generated the experimental data	generated the experimental data	Performed the experiments	Investigation	YES
4409371	25909330	AM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to discussion	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409371	25909330	AM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to discussion	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409371	25909330	AM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to discussion	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409371	25909330	AM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to discussion	Contributed to discussion	-	-	NO
4409371	25909330	AMVK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to discussion	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409371	25909330	AMVK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to discussion	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409371	25909330	AMVK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to discussion	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409371	25909330	AMVK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to discussion	Contributed to discussion	-	-	NO
4409371	25909330	KDS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to discussion	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409371	25909330	KDS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to discussion	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409371	25909330	KDS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to discussion	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409371	25909330	KDS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to discussion	Contributed to discussion	-	-	NO
4409371	25909330	PI	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to discussion	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409371	25909330	PI	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to discussion	Analyzed the data	Analyzed the data	Formal analysis	YES
4409371	25909330	PI	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to discussion	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409371	25909330	PI	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to discussion	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409371	25909330	PI	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to discussion	Contributed to discussion	-	-	NO
4409371	25909330	SM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to discussion	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409371	25909330	SM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to discussion	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409371	25909330	SM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to discussion	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409371	25909330	SM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to discussion	Contributed to discussion	-	-	NO
4409371	25909330	SP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to discussion	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409371	25909330	SP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to discussion	Performed the experiments	Performed the experiments	Investigation	YES
4409371	25909330	SP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to discussion	Analyzed the data	Analyzed the data	Formal analysis	YES
4409371	25909330	SP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to discussion	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409371	25909330	SP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to discussion	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409371	25909330	SP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to discussion	Contributed to discussion	-	-	NO
4077629	25006546	DG	2	performed the radiosynthesis and pharmacological controls|drafted the manuscript|conceived the study and participated in its design and coordination	performed the radiosynthesis and pharmacological controls	Performed the experiments	Investigation	YES
4077629	25006546	DG	2	performed the radiosynthesis and pharmacological controls|drafted the manuscript|conceived the study and participated in its design and coordination	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4077629	25006546	DG	2	performed the radiosynthesis and pharmacological controls|drafted the manuscript|conceived the study and participated in its design and coordination	conceived the study and participated in its design and coordination	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
4077629	25006546	IB	2	have recruited the patients and performed clinical examinations|conceived the study and participated in its design and coordination	have recruited the patients and performed clinical examinations	Performed the experiments	Investigation	YES
4077629	25006546	IB	2	have recruited the patients and performed clinical examinations|conceived the study and participated in its design and coordination	conceived the study and participated in its design and coordination	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
4077629	25006546	JPC	2	performed data acquisition and analysis|drafted the manuscript|conceived the study and participated in its design and coordination	performed data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4077629	25006546	JPC	2	performed data acquisition and analysis|drafted the manuscript|conceived the study and participated in its design and coordination	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4077629	25006546	JPC	2	performed data acquisition and analysis|drafted the manuscript|conceived the study and participated in its design and coordination	conceived the study and participated in its design and coordination	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
4077629	25006546	JV	2	performed the radiosynthesis and pharmacological controls|drafted the manuscript	performed the radiosynthesis and pharmacological controls	Performed the experiments	Investigation	YES
4077629	25006546	JV	2	performed the radiosynthesis and pharmacological controls|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4077629	25006546	MJR	2	performed data acquisition and analysis|drafted the manuscript|conceived the study and participated in its design and coordination	performed data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4077629	25006546	MJR	2	performed data acquisition and analysis|drafted the manuscript|conceived the study and participated in its design and coordination	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4077629	25006546	MJR	2	performed data acquisition and analysis|drafted the manuscript|conceived the study and participated in its design and coordination	conceived the study and participated in its design and coordination	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
4077629	25006546	MK	2	performed the precursor production	performed the precursor production	Performed the experiments	Investigation	YES
4077629	25006546	NA	2	performed the radiosynthesis and pharmacological controls|performed statistical analysis|drafted the manuscript	performed the radiosynthesis and pharmacological controls	Performed the experiments	Investigation	YES
4077629	25006546	NA	2	performed the radiosynthesis and pharmacological controls|performed statistical analysis|drafted the manuscript	performed statistical analysis	Analyzed the data	Formal analysis	YES
4077629	25006546	NA	2	performed the radiosynthesis and pharmacological controls|performed statistical analysis|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4077629	25006546	SB	2	performed the precursor production	performed the precursor production	Performed the experiments	Investigation	YES
4077629	25006546	SD	2	have recruited the patients and performed clinical examinations|conceived the study and participated in its design and coordination	have recruited the patients and performed clinical examinations	Performed the experiments	Investigation	YES
4077629	25006546	SD	2	have recruited the patients and performed clinical examinations|conceived the study and participated in its design and coordination	conceived the study and participated in its design and coordination	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
4077629	25006546	VC	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5641392	29067035	All authors	2	reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5641392	29067035	CH	2	provided advice on the experimental design	provided advice on the experimental design	Conceived and designed the experiments	Methodology	YES
5641392	29067035	CZ	2	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5641392	29067035	HL	2	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5641392	29067035	HZ	2	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5641392	29067035	JL	2	provided advice on the experimental design	provided advice on the experimental design	Conceived and designed the experiments	Methodology	YES
5641392	29067035	JQ	2	provided advice on the experimental design	provided advice on the experimental design	Conceived and designed the experiments	Methodology	YES
5641392	29067035	JS	2	performed phenotype measurements|analyzed data|wrote the manuscript	performed phenotype measurements	Performed the experiments	Investigation	YES
5641392	29067035	JS	2	performed phenotype measurements|analyzed data|wrote the manuscript	analyzed data	Analyzed the data	Formal analysis	YES
5641392	29067035	JS	2	performed phenotype measurements|analyzed data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5641392	29067035	JW	2	conceived and designed the study|wrote the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5641392	29067035	JW	2	conceived and designed the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5641392	29067035	SW	2	performed phenotype measurements	performed phenotype measurements	Performed the experiments	Investigation	YES
5641392	29067035	YX	2	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
6060422	30047573	AB	2	performed proteomic and microbiome analysis, data interpretation and helped with manuscript writing	performed proteomic and microbiome analysis, data interpretation and helped with manuscript writing	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6060422	30047573	EH	2	performed the measurements of drugs	performed the measurements of drugs	Performed the experiments	Investigation	YES
6060422	30047573	GBL	2	performed the experiments on cellular phenotyping	performed the experiments on cellular phenotyping	Performed the experiments	Investigation	YES
6060422	30047573	JC	2	were involved in the recruitment and follow-up of the participants	were involved in the recruitment and follow-up of the participants	Performed the experiments	Investigation	YES
6060422	30047573	JK	2	contributed to the study design|was the clinical leader	contributed to the study design	Conceived and designed the experiments	Methodology	YES
6060422	30047573	JK	2	contributed to the study design|was the clinical leader	was the clinical leader	-	Supervision	YES
6060422	30047573	JL	2	contributed to the study design|performed the data analysis, interpretation of the results and manuscript drafting	contributed to the study design	Conceived and designed the experiments	Methodology	YES
6060422	30047573	JL	2	contributed to the study design|performed the data analysis, interpretation of the results and manuscript drafting	performed the data analysis, interpretation of the results and manuscript drafting	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6060422	30047573	JM	2	were involved in the recruitment and follow-up of the participants	were involved in the recruitment and follow-up of the participants	Performed the experiments	Investigation	YES
6060422	30047573	JO	2	was the laboratory manager of the nairobi laboratory	was the laboratory manager of the nairobi laboratory	-	Project administration	YES
6060422	30047573	KB	2	performed proteomic and microbiome analysis, data interpretation and helped with manuscript writing	performed proteomic and microbiome analysis, data interpretation and helped with manuscript writing	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6060422	30047573	KF	2	was the principal investigator of the study	was the principal investigator of the study	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
6060422	30047573	KR	2	contributed to the study design	contributed to the study design	Conceived and designed the experiments	Methodology	YES
6060422	30047573	LM	2	performed the experiments on cellular phenotyping	performed the experiments on cellular phenotyping	Performed the experiments	Investigation	YES
6060422	30047573	LR	2	performed proteomic and microbiome analysis, data interpretation and helped with manuscript writing	performed proteomic and microbiome analysis, data interpretation and helped with manuscript writing	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6060422	30047573	MA	2	were involved in the recruitment and follow-up of the participants	were involved in the recruitment and follow-up of the participants	Performed the experiments	Investigation	YES
6060422	30047573	MK	2	contributed to the study design|was the medical officer of the study in charge of following participants	contributed to the study design	Conceived and designed the experiments	Methodology	YES
6060422	30047573	MK	2	contributed to the study design|was the medical officer of the study in charge of following participants	was the medical officer of the study in charge of following participants	-	-	NO
6060422	30047573	SM	2	performed proteomic and microbiome analysis, data interpretation and helped with manuscript writing	performed proteomic and microbiome analysis, data interpretation and helped with manuscript writing	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6060422	30047573	YC	2	performed the measurements of drugs	performed the measurements of drugs	Performed the experiments	Investigation	YES
1790633	17299599	CS	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1790633	17299599	EC	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1790633	17299599	EC	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1790633	17299599	JC	PLoS5	Conceived and designed the experiments|Analyzed the data|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1790633	17299599	JC	PLoS5	Conceived and designed the experiments|Analyzed the data|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1790633	17299599	JC	PLoS5	Conceived and designed the experiments|Analyzed the data|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1790633	17299599	JC	PLoS5	Conceived and designed the experiments|Analyzed the data|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1790633	17299599	JD	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1790633	17299599	KK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1790633	17299599	KK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1790633	17299599	KK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1790633	17299599	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1790633	17299599	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1790633	17299599	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1790633	17299599	NF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1790633	17299599	NF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1790633	17299599	NF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1790633	17299599	NF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1790633	17299599	SG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1790633	17299599	SG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1790633	17299599	SG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1790633	17299599	TL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5460546	28583089	AS	2	conceived and coordinated the study and contributed to the writing of the manuscript	conceived and coordinated the study and contributed to the writing of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Project administration|Writing - Original Draft	YES
5460546	28583089	BQT	2	developed genetic materials, carried out phenotyping, and contributed to the writing of the manuscript	developed genetic materials, carried out phenotyping, and contributed to the writing of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5460546	28583089	CdSL	2	developed genetic materials, carried out phenotyping, and contributed to the writing of the manuscript	developed genetic materials, carried out phenotyping, and contributed to the writing of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5460546	28583089	DB	2	developed genetic materials, carried out phenotyping, and contributed to the writing of the manuscript	developed genetic materials, carried out phenotyping, and contributed to the writing of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5460546	28583089	FB	2	performed all statistical analyses, and wrote most of the paper	performed all statistical analyses, and wrote most of the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5460546	28583089	IPC	2	developed genetic materials, carried out phenotyping, and contributed to the writing of the manuscript	developed genetic materials, carried out phenotyping, and contributed to the writing of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5460546	28583089	IV	2	developed genetic materials, carried out phenotyping, and contributed to the writing of the manuscript	developed genetic materials, carried out phenotyping, and contributed to the writing of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5460546	28583089	LR	2	conceived and coordinated the study and contributed to the writing of the manuscript	conceived and coordinated the study and contributed to the writing of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Project administration|Writing - Original Draft	YES
5460546	28583089	MB	2	contributed to the development of statistical analyses and writing of the manuscript	contributed to the development of statistical analyses and writing of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5460546	28583089	MJA	2	developed genetic materials, carried out phenotyping, and contributed to the writing of the manuscript	developed genetic materials, carried out phenotyping, and contributed to the writing of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5460546	28583089	NN	2	performed all statistical analyses, and wrote most of the paper	performed all statistical analyses, and wrote most of the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5460546	28583089	PA	2	developed genetic materials, carried out phenotyping, and contributed to the writing of the manuscript	developed genetic materials, carried out phenotyping, and contributed to the writing of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5460546	28583089	PL	2	developed genetic materials, carried out phenotyping, and contributed to the writing of the manuscript	developed genetic materials, carried out phenotyping, and contributed to the writing of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5460546	28583089	SM	2	developed genetic materials, carried out phenotyping, and contributed to the writing of the manuscript	developed genetic materials, carried out phenotyping, and contributed to the writing of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5460546	28583089	TP	2	developed genetic materials, carried out phenotyping, and contributed to the writing of the manuscript	developed genetic materials, carried out phenotyping, and contributed to the writing of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4078320	25006545	AS	2	are responsible for the hl pigs at the university of wisconsin	are responsible for the hl pigs at the university of wisconsin	-	-	NO
4078320	25006545	CK	2	are responsible for the hl pigs at the university of wisconsin	are responsible for the hl pigs at the university of wisconsin	-	-	NO
4078320	25006545	CL	2	performed the quantitative immunohistology	performed the quantitative immunohistology	Performed the experiments	Investigation	YES
4078320	25006545	GE	2	performed the necropsies	performed the necropsies	Performed the experiments	Investigation	YES
4078320	25006545	KB	2	imaged the pigs	imaged the pigs	Analyzed the data	Visualization	YES
4078320	25006545	LJ	2	supervised the performance of the experiments and wrote the manuscript	supervised the performance of the experiments and wrote the manuscript	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Original Draft	YES
4078320	25006545	MK	2	harvested the tissue and prepared it for histology	harvested the tissue and prepared it for histology	Performed the experiments	Investigation	YES
4078320	25006545	RAGE	2	biology and collaborated on the development of the imaging antibody	biology and collaborated on the development of the imaging antibody	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
4078320	25006545	YT	2	prepared the radiotracer and did the well counting and histological staining	prepared the radiotracer and did the well counting and histological staining	Performed the experiments	Investigation	YES
4409372	25910078	AC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409372	25910078	AC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4409372	25910078	AC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4409372	25910078	AC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409372	25910078	FC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409372	25910078	FF	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409372	25910078	GD	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409372	25910078	GR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409372	25910078	GR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409372	25910078	GR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409372	25910078	GR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409372	25910078	GR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409372	25910078	KCS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409372	25910078	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409372	25910078	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4409372	25910078	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409372	25910078	PG	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4549939	26303917	A.C.	2	developed the cable application example	developed the cable application example	-	-	NO
4549939	26303917	A.R.C.	2	working on recasting the second-order technique in the general theory of normal forms	working on recasting the second-order technique in the general theory of normal forms	-	-	NO
4549939	26303917	All authors	2	helped to draft the manuscript and gave final approval for publication	helped to draft the manuscript and gave final approval for publication	Wrote the paper	Writing - Original Draft	YES
4549939	26303917	D.J.W.	2	working on recasting the second-order technique in the general theory of normal forms	working on recasting the second-order technique in the general theory of normal forms	-	-	NO
4549939	26303917	S.A.N.	2	working on recasting the second-order technique in the general theory of normal forms|developed the cable application example	working on recasting the second-order technique in the general theory of normal forms	-	-	NO
4549939	26303917	S.A.N.	2	working on recasting the second-order technique in the general theory of normal forms|developed the cable application example	developed the cable application example	-	-	NO
4549939	26303917	T.L.H.	2	developed the cable application example	developed the cable application example	-	-	NO
5641395	29067030	LQ	2	designed the primers and performed experiments	designed the primers and performed experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5641395	29067030	QD	2	designed the primers and performed experiments	designed the primers and performed experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5641395	29067030	SF	2	designed the study, analyzed the data and wrote the manuscript	designed the study, analyzed the data and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5641395	29067030	TR	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5641395	29067030	YW	2	designed the primers and performed experiments	designed the primers and performed experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5641395	29067030	ZL	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5641395	29067030	ZT	2	designed the study, analyzed the data and wrote the manuscript	designed the study, analyzed the data and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
1790699	17299590	CF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1790699	17299590	CF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1790699	17299590	CF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1790699	17299590	CF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1790699	17299590	CF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1790699	17299590	JF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1790699	17299590	JF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1790699	17299590	JF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1790699	17299590	JF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1790699	17299590	JF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409373	25909447	GS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409373	25909447	GS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409373	25909447	GS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409373	25909447	MC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409373	25909447	MC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409373	25909447	MC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409373	25909447	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409373	25909447	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409373	25909447	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409373	25909447	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409373	25909447	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409373	25909447	TD	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409373	25909447	TD	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409373	25909447	TD	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409373	25909447	UL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409373	25909447	UL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409373	25909447	UL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4549940	26303916	Both authors	2	contributed to the drafting of the manuscript and gave final approval for publication	contributed to the drafting of the manuscript and gave final approval for publication	Wrote the paper	Writing - Original Draft	YES
4549940	26303916	K.W.	2	contributed the material giving a general overview of bayesian system identification and aided the articles revision	contributed the material giving a general overview of bayesian system identification and aided the articles revision	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Resources|Writing - Review & Editing	YES
5641402	29067036	HZ	2	reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5641402	29067036	JC	2	conducted the experiments, analyzed the data and drafted manuscript	conducted the experiments, analyzed the data and drafted manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5641402	29067036	MT	2	conceived the study|reviewed and edited the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5641402	29067036	MT	2	conceived the study|reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5641402	29067036	XZ	2	participated in the experiment	participated in the experiment	Performed the experiments	Investigation	YES
5460551	28583064	BS	PLoS52	participated in the design and or discussion of the study|performed genome gap closure, gene annotation and comparative genome analysis|analyzed the data	participated in the design and or discussion of the study	Conceived and designed the experiments	Methodology	YES
5460551	28583064	BS	PLoS52	participated in the design and or discussion of the study|performed genome gap closure, gene annotation and comparative genome analysis|analyzed the data	performed genome gap closure, gene annotation and comparative genome analysis	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5460551	28583064	BS	PLoS52	participated in the design and or discussion of the study|performed genome gap closure, gene annotation and comparative genome analysis|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5460551	28583064	CZ	PLoS52	participated in the design and or discussion of the study|carried out the major experiments in gene deletion mutant and transcriptomic analysis|analyzed the data	participated in the design and or discussion of the study	Conceived and designed the experiments	Methodology	YES
5460551	28583064	CZ	PLoS52	participated in the design and or discussion of the study|carried out the major experiments in gene deletion mutant and transcriptomic analysis|analyzed the data	carried out the major experiments in gene deletion mutant and transcriptomic analysis	Performed the experiments	Investigation	YES
5460551	28583064	CZ	PLoS52	participated in the design and or discussion of the study|carried out the major experiments in gene deletion mutant and transcriptomic analysis|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5460551	28583064	FS	PLoS52	participated in the design and or discussion of the study	participated in the design and or discussion of the study	Conceived and designed the experiments	Methodology	YES
5460551	28583064	HZ	PLoS52	participated in the design and or discussion of the study|directed the sequencing and comparative genome analysis|revised it for important improvement	participated in the design and or discussion of the study	Conceived and designed the experiments	Methodology	YES
5460551	28583064	HZ	PLoS52	participated in the design and or discussion of the study|directed the sequencing and comparative genome analysis|revised it for important improvement	directed the sequencing and comparative genome analysis	Performed the experiments	Investigation|Supervision	YES
5460551	28583064	HZ	PLoS52	participated in the design and or discussion of the study|directed the sequencing and comparative genome analysis|revised it for important improvement	revised it for important improvement	Wrote the paper	Writing - Review & Editing	YES
5460551	28583064	LC	PLoS52	participated in the design and or discussion of the study|analyzed the data	participated in the design and or discussion of the study	Conceived and designed the experiments	Methodology	YES
5460551	28583064	LC	PLoS52	participated in the design and or discussion of the study|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5460551	28583064	LX	PLoS52	participated in the design and or discussion of the study|revised it for important improvement	participated in the design and or discussion of the study	Conceived and designed the experiments	Methodology	YES
5460551	28583064	LX	PLoS52	participated in the design and or discussion of the study|revised it for important improvement	revised it for important improvement	Wrote the paper	Writing - Review & Editing	YES
5460551	28583064	MY	PLoS52	participated in the design and or discussion of the study	participated in the design and or discussion of the study	Conceived and designed the experiments	Methodology	YES
5460551	28583064	QS	PLoS52	participated in the design and or discussion of the study|revised it for important improvement	participated in the design and or discussion of the study	Conceived and designed the experiments	Methodology	YES
5460551	28583064	QS	PLoS52	participated in the design and or discussion of the study|revised it for important improvement	revised it for important improvement	Wrote the paper	Writing - Review & Editing	YES
5460551	28583064	TL	PLoS52	participated in the design and or discussion of the study|analyzed the data	participated in the design and or discussion of the study	Conceived and designed the experiments	Methodology	YES
5460551	28583064	TL	PLoS52	participated in the design and or discussion of the study|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5460551	28583064	WB	PLoS52	participated in the design and or discussion of the study	participated in the design and or discussion of the study	Conceived and designed the experiments	Methodology	YES
5460551	28583064	WG	PLoS52	assisted the genome sequencing and gene annotation	assisted the genome sequencing and gene annotation	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5460551	28583064	WH	PLoS52	assisted the genome sequencing and gene annotation	assisted the genome sequencing and gene annotation	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5460551	28583064	XP	PLoS52	participated in the design and or discussion of the study	participated in the design and or discussion of the study	Conceived and designed the experiments	Methodology	YES
5460551	28583064	YW	PLoS52	constructed gene reverse mutants and analyzed their growth curves	constructed gene reverse mutants and analyzed their growth curves	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4078321	25006543	AJ	2	designed the study, performed the monte carlo simulations and drafted the manuscript	designed the study, performed the monte carlo simulations and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4078321	25006543	Both authors	2	contributed to the scientific and intellectual discussion and interpretation of the data and revision of the manuscript	contributed to the scientific and intellectual discussion and interpretation of the data and revision of the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
4410522	26124545	Ashwini Hariharan	7	Experimental	Experimental	-	-	NO
4410522	26124545	G Jagtap	7	Writing of manuscript & supervision on experiment	Writing of manuscript & supervision on experiment	Wrote the paper	Supervision|Writing - Original Draft	YES
4410522	26124545	Shruthi Shetty	7	Experimental|Writing of manuscript, Aarti	Experimental	-	-	NO
4410522	26124545	Shruthi Shetty	7	Experimental|Writing of manuscript, Aarti	Writing of manuscript, Aarti	Wrote the paper	Writing - Original Draft	YES
4410522	26124545	Trupti Shirole	7	Biochemical studies	Biochemical studies	Performed the experiments	Investigation	YES
4409374	25910059	BK	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409374	25910059	FF	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409374	25910059	FF	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409374	25910059	FF	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409374	25910059	FF	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409374	25910059	MY	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409374	25910059	MY	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4409374	25910059	MY	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409374	25910059	PD	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4409374	25910059	PD	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5641410	29067029	P-FY	2	mainly contributed to collecting some very valuable walnut samples	mainly contributed to collecting some very valuable walnut samples	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5641410	29067029	Q-WL	2	is the corresponding author, he proposed this study subject, designed the relevant experiments, and also partially funded this study	is the corresponding author, he proposed this study subject, designed the relevant experiments, and also partially funded this study	Conceived and designed the experiments	Conceptualization|Funding acquisition|Methodology	YES
5641410	29067029	X-YM	2	is the first author and corresponding author, and his contributions are including sample collection, experiment performing, data analysis, paper writing and also partially funded this study	is the first author and corresponding author, and his contributions are including sample collection, experiment performing, data analysis, paper writing and also partially funded this study	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Funding acquisition|Investigation|Resources	YES
1790700	17299589	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1790700	17299589	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1790700	17299589	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1790700	17299589	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1790700	17299589	GM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1790700	17299589	GM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4410523	26124546	J Sanya	7	Participated in the revision of the manuscript and analysis of the result	Participated in the revision of the manuscript and analysis of the result	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4410523	26124546	M Ogundele	7	Main author and investigator that designed the experiments and wrote the manuscript, Olurotimi	Main author and investigator that designed the experiments and wrote the manuscript, Olurotimi	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4078388	25006548	AJ	2	carried out the experiments and wrote the manuscript	carried out the experiments and wrote the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4078388	25006548	BLB	2	was involved in the experiments and the analysis of the transfected cells and revised the manuscript	was involved in the experiments and the analysis of the transfected cells and revised the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4078388	25006548	MBe	2	designed the studies and analysed the results as well as wrote parts of the manuscript	designed the studies and analysed the results as well as wrote parts of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4078388	25006548	MBr	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4078388	25006548	RS	2	was involved in the design and analysis of the experiments and revised the manuscript	was involved in the design and analysis of the experiments and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
4549942	26303924	All three authors	2	were equally involved in the drafting, redrafting and preparation of all sections of the final version that was accepted for publication	were equally involved in the drafting, redrafting and preparation of all sections of the final version that was accepted for publication	Wrote the paper	Writing - Original Draft	YES
4549942	26303924	B.W.	2	led the review and classification of the methods available to carry it out in practice	led the review and classification of the methods available to carry it out in practice	Performed the experiments	Investigation	YES
4549942	26303924	D.J.E.	2	initiated the plan for the paper and its overall structure	initiated the plan for the paper and its overall structure	Conceived and designed the experiments	Conceptualization	YES
5461527	28589863	HJM	2	implemented the project	implemented the project	Performed the experiments	Investigation	YES
1790701	17299592	CN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1790701	17299592	CN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1790701	17299592	CN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1790701	17299592	CN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1790701	17299592	CN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1790701	17299592	RF	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1790701	17299592	RF	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1790701	17299592	RF	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1790701	17299592	RK	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1790701	17299592	RK	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409375	25909586	BHW	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409375	25909586	BHW	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409375	25909586	JJ	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409375	25909586	PCW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409375	25909586	WPG	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409375	25909586	WPG	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409375	25909586	WPG	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409375	25909586	XLX	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409375	25909586	XMY	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5641424	29067037	AC	PLoS5	Conceived and designed the experiments|Processing, analysis and interpretation|Analyzed the data|Prepared the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5641424	29067037	AC	PLoS5	Conceived and designed the experiments|Processing, analysis and interpretation|Analyzed the data|Prepared the manuscript	Processing, analysis and interpretation	Analyzed the data	Formal analysis	YES
5641424	29067037	AC	PLoS5	Conceived and designed the experiments|Processing, analysis and interpretation|Analyzed the data|Prepared the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
5641424	29067037	AC	PLoS5	Conceived and designed the experiments|Processing, analysis and interpretation|Analyzed the data|Prepared the manuscript	Prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5641424	29067037	AL	PLoS5	Conceived and designed the experiments|Data acquisition of plant pathogen and diagnostic tests|Edited the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5641424	29067037	AL	PLoS5	Conceived and designed the experiments|Data acquisition of plant pathogen and diagnostic tests|Edited the manuscript	Data acquisition of plant pathogen and diagnostic tests	Performed the experiments	Investigation	YES
5641424	29067037	AL	PLoS5	Conceived and designed the experiments|Data acquisition of plant pathogen and diagnostic tests|Edited the manuscript	Edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5641424	29067037	LDB	PLoS5	Data acquisition of plant pathogen and diagnostic tests|Edited the manuscript	Data acquisition of plant pathogen and diagnostic tests	Performed the experiments	Investigation	YES
5641424	29067037	LDB	PLoS5	Data acquisition of plant pathogen and diagnostic tests|Edited the manuscript	Edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5641424	29067037	YA	PLoS5	Conceived and designed the experiments|Processing, analysis and interpretation|Analyzed the data|Prepared the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5641424	29067037	YA	PLoS5	Conceived and designed the experiments|Processing, analysis and interpretation|Analyzed the data|Prepared the manuscript	Processing, analysis and interpretation	Analyzed the data	Formal analysis	YES
5641424	29067037	YA	PLoS5	Conceived and designed the experiments|Processing, analysis and interpretation|Analyzed the data|Prepared the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
5641424	29067037	YA	PLoS5	Conceived and designed the experiments|Processing, analysis and interpretation|Analyzed the data|Prepared the manuscript	Prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
4086353	25024931	ASWG	2	were involved in study design, implementation, data collection, data analysis, and manuscript preparation	were involved in study design, implementation, data collection, data analysis, and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4086353	25024931	BMM	2	were involved in study design, implementation, data collection, data analysis, and manuscript preparation	were involved in study design, implementation, data collection, data analysis, and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4086353	25024931	DCEN	2	were involved in study design, implementation, data collection, data analysis, and manuscript preparation	were involved in study design, implementation, data collection, data analysis, and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4086353	25024931	KHT	2	were involved in radioembolization, clinical care, and manuscript preparation	were involved in radioembolization, clinical care, and manuscript preparation	Wrote the paper	Writing - Original Draft	YES
4086353	25024931	PKHC	2	were involved in radioembolization, clinical care, and manuscript preparation	were involved in radioembolization, clinical care, and manuscript preparation	Wrote the paper	Writing - Original Draft	YES
4086353	25024931	YHK	2	were involved in study design, implementation, data collection, data analysis, and manuscript preparation	were involved in study design, implementation, data collection, data analysis, and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4086353	25024931	YT	2	were involved in study design, implementation, data collection, data analysis, and manuscript preparation	were involved in study design, implementation, data collection, data analysis, and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4607701	26347536	A.P.	2	formulated hypothesis, designed and conducted experiments	formulated hypothesis, designed and conducted experiments	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
4607701	26347536	All	2	were involved in paper preparation	were involved in paper preparation	-	-	NO
4607701	26347536	D.D.	2	formulated hypothesis, designed and conducted experiments	formulated hypothesis, designed and conducted experiments	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
4607701	26347536	J.B.	2	provided and processed observational data and validated model results	provided and processed observational data and validated model results	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Investigation|Methodology|Resources|Validation	YES
4607701	26347536	M.-L.T.	2	provided and processed observational data and validated model results	provided and processed observational data and validated model results	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Investigation|Methodology|Resources|Validation	YES
4607701	26347536	R.K.	2	provided and processed observational data and validated model results	provided and processed observational data and validated model results	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Investigation|Methodology|Resources|Validation	YES
1790702	17299584	AL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1790702	17299584	AL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1790702	17299584	AL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1790702	17299584	CW	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1790702	17299584	FB	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1790702	17299584	GC	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1790702	17299584	GT	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1790702	17299584	GT	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1790702	17299584	JA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1790702	17299584	JA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1790702	17299584	JA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409376	25909629	CKC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409376	25909629	CKC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409376	25909629	CKC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409376	25909629	CKC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409376	25909629	CPK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409376	25909629	DMW	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409376	25909629	JAB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409376	25909629	JJB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409376	25909629	JJB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409376	25909629	JJB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409376	25909629	KA	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409376	25909629	PLW	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409376	25909629	RCB	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409376	25909629	RCB	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409376	25909629	SJK	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409376	25909629	SLW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409376	25909629	SLW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409376	25909629	SLW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409376	25909629	SLW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409376	25909629	SRT	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5461532	28589858	AM	2	gave statistical guidance	gave statistical guidance	Analyzed the data	Formal analysis|Supervision	YES
5461532	28589858	DS	2	did the research and writing	did the research and writing	Wrote the paper	-	YES
5461532	28589858	ECC	2	did the research and writing	did the research and writing	Wrote the paper	-	YES
5461532	28589858	JHC	2	gave statistical guidance	gave statistical guidance	Analyzed the data	Formal analysis|Supervision	YES
4086443	25024930	FD	2	performed statistical analysis and participated in the design of the study	performed statistical analysis and participated in the design of the study	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
4086443	25024930	LB	2	performed fluorescence and confocal microscopy	performed fluorescence and confocal microscopy	Performed the experiments	Investigation	YES
4086443	25024930	LG	2	conceived and coordinated the study and carried out the experiments	conceived and coordinated the study and carried out the experiments	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Project administration	YES
4086443	25024930	ND	2	prepared the nanobodies	prepared the nanobodies	-	-	NO
4086443	25024930	TB	2	constructed the lentiviral vectors for transduction	constructed the lentiviral vectors for transduction	Performed the experiments	Investigation	YES
4086443	25024930	TL	2	participated in the design and coordination of the study and helped to draft the manuscript	participated in the design and coordination of the study and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft	YES
6067081	30063287	AGW	PLoS52	performed the experiments|wrote the first draft of the manuscript|contributed to the writing of the manuscript|agreed with the manuscripts results and conclusions|assisted with design of analyses and interpretation of result	performed the experiments	Performed the experiments	Investigation	YES
6067081	30063287	AGW	PLoS52	performed the experiments|wrote the first draft of the manuscript|contributed to the writing of the manuscript|agreed with the manuscripts results and conclusions|assisted with design of analyses and interpretation of result	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
6067081	30063287	AGW	PLoS52	performed the experiments|wrote the first draft of the manuscript|contributed to the writing of the manuscript|agreed with the manuscripts results and conclusions|assisted with design of analyses and interpretation of result	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
6067081	30063287	AGW	PLoS52	performed the experiments|wrote the first draft of the manuscript|contributed to the writing of the manuscript|agreed with the manuscripts results and conclusions|assisted with design of analyses and interpretation of result	agreed with the manuscripts results and conclusions	-	-	NO
6067081	30063287	AGW	PLoS52	performed the experiments|wrote the first draft of the manuscript|contributed to the writing of the manuscript|agreed with the manuscripts results and conclusions|assisted with design of analyses and interpretation of result	assisted with design of analyses and interpretation of result	Conceived and designed the experiments|Analyzed the data	Formal analysis	YES
6067081	30063287	CF	PLoS52	analysed the data|contributed to the writing of the manuscript|assisted with design of analyses and interpretation of result	analysed the data	Analyzed the data	Formal analysis	YES
6067081	30063287	CF	PLoS52	analysed the data|contributed to the writing of the manuscript|assisted with design of analyses and interpretation of result	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
6067081	30063287	CF	PLoS52	analysed the data|contributed to the writing of the manuscript|assisted with design of analyses and interpretation of result	assisted with design of analyses and interpretation of result	Conceived and designed the experiments|Analyzed the data	Formal analysis	YES
6067081	30063287	ELC	PLoS52	conceived and designed the experiments|performed the experiments|wrote the first draft of the manuscript|contributed to the writing of the manuscript|agreed with the manuscripts results and conclusions|assisted with design of analyses and interpretation of result	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6067081	30063287	ELC	PLoS52	conceived and designed the experiments|performed the experiments|wrote the first draft of the manuscript|contributed to the writing of the manuscript|agreed with the manuscripts results and conclusions|assisted with design of analyses and interpretation of result	performed the experiments	Performed the experiments	Investigation	YES
6067081	30063287	ELC	PLoS52	conceived and designed the experiments|performed the experiments|wrote the first draft of the manuscript|contributed to the writing of the manuscript|agreed with the manuscripts results and conclusions|assisted with design of analyses and interpretation of result	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
6067081	30063287	ELC	PLoS52	conceived and designed the experiments|performed the experiments|wrote the first draft of the manuscript|contributed to the writing of the manuscript|agreed with the manuscripts results and conclusions|assisted with design of analyses and interpretation of result	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
6067081	30063287	ELC	PLoS52	conceived and designed the experiments|performed the experiments|wrote the first draft of the manuscript|contributed to the writing of the manuscript|agreed with the manuscripts results and conclusions|assisted with design of analyses and interpretation of result	agreed with the manuscripts results and conclusions	-	-	NO
6067081	30063287	ELC	PLoS52	conceived and designed the experiments|performed the experiments|wrote the first draft of the manuscript|contributed to the writing of the manuscript|agreed with the manuscripts results and conclusions|assisted with design of analyses and interpretation of result	assisted with design of analyses and interpretation of result	Conceived and designed the experiments|Analyzed the data	Formal analysis	YES
6067081	30063287	JO	PLoS52	performed the experiments|contributed to the writing of the manuscript|agreed with the manuscripts results and conclusions	performed the experiments	Performed the experiments	Investigation	YES
6067081	30063287	JO	PLoS52	performed the experiments|contributed to the writing of the manuscript|agreed with the manuscripts results and conclusions	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
6067081	30063287	JO	PLoS52	performed the experiments|contributed to the writing of the manuscript|agreed with the manuscripts results and conclusions	agreed with the manuscripts results and conclusions	-	-	NO
6067081	30063287	KH	PLoS52	analysed the data|wrote the first draft of the manuscript|agreed with the manuscripts results and conclusions	analysed the data	Analyzed the data	Formal analysis	YES
6067081	30063287	KH	PLoS52	analysed the data|wrote the first draft of the manuscript|agreed with the manuscripts results and conclusions	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
6067081	30063287	KH	PLoS52	analysed the data|wrote the first draft of the manuscript|agreed with the manuscripts results and conclusions	agreed with the manuscripts results and conclusions	-	-	NO
6067081	30063287	MM	PLoS52	performed the experiments|contributed to the writing of the manuscript|agreed with the manuscripts results and conclusions	performed the experiments	Performed the experiments	Investigation	YES
6067081	30063287	MM	PLoS52	performed the experiments|contributed to the writing of the manuscript|agreed with the manuscripts results and conclusions	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
6067081	30063287	MM	PLoS52	performed the experiments|contributed to the writing of the manuscript|agreed with the manuscripts results and conclusions	agreed with the manuscripts results and conclusions	-	-	NO
6067081	30063287	MN	PLoS52	conceived and designed the experiments|performed the experiments|analysed the data|wrote the first draft of the manuscript|contributed to the writing of the manuscript|agreed with the manuscripts results and conclusions|assisted with design of analyses and interpretation of result	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6067081	30063287	MN	PLoS52	conceived and designed the experiments|performed the experiments|analysed the data|wrote the first draft of the manuscript|contributed to the writing of the manuscript|agreed with the manuscripts results and conclusions|assisted with design of analyses and interpretation of result	performed the experiments	Performed the experiments	Investigation	YES
6067081	30063287	MN	PLoS52	conceived and designed the experiments|performed the experiments|analysed the data|wrote the first draft of the manuscript|contributed to the writing of the manuscript|agreed with the manuscripts results and conclusions|assisted with design of analyses and interpretation of result	analysed the data	Analyzed the data	Formal analysis	YES
6067081	30063287	MN	PLoS52	conceived and designed the experiments|performed the experiments|analysed the data|wrote the first draft of the manuscript|contributed to the writing of the manuscript|agreed with the manuscripts results and conclusions|assisted with design of analyses and interpretation of result	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
6067081	30063287	MN	PLoS52	conceived and designed the experiments|performed the experiments|analysed the data|wrote the first draft of the manuscript|contributed to the writing of the manuscript|agreed with the manuscripts results and conclusions|assisted with design of analyses and interpretation of result	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
6067081	30063287	MN	PLoS52	conceived and designed the experiments|performed the experiments|analysed the data|wrote the first draft of the manuscript|contributed to the writing of the manuscript|agreed with the manuscripts results and conclusions|assisted with design of analyses and interpretation of result	agreed with the manuscripts results and conclusions	-	-	NO
6067081	30063287	MN	PLoS52	conceived and designed the experiments|performed the experiments|analysed the data|wrote the first draft of the manuscript|contributed to the writing of the manuscript|agreed with the manuscripts results and conclusions|assisted with design of analyses and interpretation of result	assisted with design of analyses and interpretation of result	Conceived and designed the experiments|Analyzed the data	Formal analysis	YES
6067081	30063287	PM	PLoS52	conceived and designed the experiments|performed the experiments|contributed to the writing of the manuscript|agreed with the manuscripts results and conclusions|assisted with design of analyses and interpretation of result	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6067081	30063287	PM	PLoS52	conceived and designed the experiments|performed the experiments|contributed to the writing of the manuscript|agreed with the manuscripts results and conclusions|assisted with design of analyses and interpretation of result	performed the experiments	Performed the experiments	Investigation	YES
6067081	30063287	PM	PLoS52	conceived and designed the experiments|performed the experiments|contributed to the writing of the manuscript|agreed with the manuscripts results and conclusions|assisted with design of analyses and interpretation of result	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
6067081	30063287	PM	PLoS52	conceived and designed the experiments|performed the experiments|contributed to the writing of the manuscript|agreed with the manuscripts results and conclusions|assisted with design of analyses and interpretation of result	agreed with the manuscripts results and conclusions	-	-	NO
6067081	30063287	PM	PLoS52	conceived and designed the experiments|performed the experiments|contributed to the writing of the manuscript|agreed with the manuscripts results and conclusions|assisted with design of analyses and interpretation of result	assisted with design of analyses and interpretation of result	Conceived and designed the experiments|Analyzed the data	Formal analysis	YES
5641554	29075272	JC	2	improve the manuscript	improve the manuscript	Wrote the paper	Writing - Review & Editing	YES
5641554	29075272	QL	2	designed the experiment|carried out the experiment|wrote the manuscript	designed the experiment	Conceived and designed the experiments	Methodology	YES
5641554	29075272	QL	2	designed the experiment|carried out the experiment|wrote the manuscript	carried out the experiment	Performed the experiments	Investigation	YES
5641554	29075272	QL	2	designed the experiment|carried out the experiment|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5641554	29075272	WD	2	designed the experiment|improve the manuscript	designed the experiment	Conceived and designed the experiments	Methodology	YES
5641554	29075272	WD	2	designed the experiment|improve the manuscript	improve the manuscript	Wrote the paper	Writing - Review & Editing	YES
5641554	29075272	YL	2	carried out the experiment	carried out the experiment	Performed the experiments	Investigation	YES
5641554	29075272	YT	2	carried out the experiment	carried out the experiment	Performed the experiments	Investigation	YES
4410525	26124548	G Esomonu	7	Involved in animal care and treatment, histological studies, Polycarp	Involved in animal care and treatment, histological studies, Polycarp	Performed the experiments	Investigation	YES
4410525	26124548	K Olaibi	7	Involved in animal care and treatment, histological studies, image and data analysis, Ugochukwu	Involved in animal care and treatment, histological studies, image and data analysis, Ugochukwu	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
4410525	26124548	M Ijomone	7	Involved in conception and study design, animal care and treatment, histological studies, image and data analysis, Olayemi	Involved in conception and study design, animal care and treatment, histological studies, image and data analysis, Olayemi	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation|Methodology|Visualization	YES
4410525	26124548	U Nwoha	7	Involved in conception and study design	Involved in conception and study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409377	25909363	DEM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Revise the manuscript critically for important intellectual content	Analyzed the data	Analyzed the data	Formal analysis	YES
4409377	25909363	DEM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Revise the manuscript critically for important intellectual content	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409377	25909363	DEM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Revise the manuscript critically for important intellectual content	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409377	25909363	DEM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Revise the manuscript critically for important intellectual content	Revise the manuscript critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4409377	25909363	PSML	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Revise the manuscript critically for important intellectual content	Performed the experiments	Performed the experiments	Investigation	YES
4409377	25909363	PSML	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Revise the manuscript critically for important intellectual content	Analyzed the data	Analyzed the data	Formal analysis	YES
4409377	25909363	PSML	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Revise the manuscript critically for important intellectual content	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409377	25909363	PSML	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Revise the manuscript critically for important intellectual content	Revise the manuscript critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4409377	25909363	SSC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Revise the manuscript critically for important intellectual content	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409377	25909363	SSC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Revise the manuscript critically for important intellectual content	Performed the experiments	Performed the experiments	Investigation	YES
4409377	25909363	SSC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Revise the manuscript critically for important intellectual content	Analyzed the data	Analyzed the data	Formal analysis	YES
4409377	25909363	SSC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Revise the manuscript critically for important intellectual content	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409377	25909363	SSC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Revise the manuscript critically for important intellectual content	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409377	25909363	SSC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Revise the manuscript critically for important intellectual content	Revise the manuscript critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4409377	25909363	WWC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Revise the manuscript critically for important intellectual content	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409377	25909363	WWC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Revise the manuscript critically for important intellectual content	Performed the experiments	Performed the experiments	Investigation	YES
4409377	25909363	WWC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Revise the manuscript critically for important intellectual content	Analyzed the data	Analyzed the data	Formal analysis	YES
4409377	25909363	WWC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Revise the manuscript critically for important intellectual content	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409377	25909363	WWC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Revise the manuscript critically for important intellectual content	Revise the manuscript critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4100568	25045603	AON	2	conceived of and contributed to the study design|performed the experiments and acquired the pet data|participated in interpretation of the data|revised the manuscript	conceived of and contributed to the study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4100568	25045603	AON	2	conceived of and contributed to the study design|performed the experiments and acquired the pet data|participated in interpretation of the data|revised the manuscript	performed the experiments and acquired the pet data	Performed the experiments	Investigation	YES
4100568	25045603	AON	2	conceived of and contributed to the study design|performed the experiments and acquired the pet data|participated in interpretation of the data|revised the manuscript	participated in interpretation of the data	Analyzed the data	Formal analysis	YES
4100568	25045603	AON	2	conceived of and contributed to the study design|performed the experiments and acquired the pet data|participated in interpretation of the data|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4100568	25045603	CS	2	conceived of and contributed to the study design|performed the experiments and acquired the pet data|analyzed the data and drafted the manuscript|participated in interpretation of the data	conceived of and contributed to the study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4100568	25045603	CS	2	conceived of and contributed to the study design|performed the experiments and acquired the pet data|analyzed the data and drafted the manuscript|participated in interpretation of the data	performed the experiments and acquired the pet data	Performed the experiments	Investigation	YES
4100568	25045603	CS	2	conceived of and contributed to the study design|performed the experiments and acquired the pet data|analyzed the data and drafted the manuscript|participated in interpretation of the data	analyzed the data and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4100568	25045603	CS	2	conceived of and contributed to the study design|performed the experiments and acquired the pet data|analyzed the data and drafted the manuscript|participated in interpretation of the data	participated in interpretation of the data	Analyzed the data	Formal analysis	YES
4100568	25045603	HI	2	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
4100568	25045603	HK	2	revised the manuscript|quantified the plasma unlabeled drug concentrations	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4100568	25045603	HK	2	revised the manuscript|quantified the plasma unlabeled drug concentrations	quantified the plasma unlabeled drug concentrations	Performed the experiments	Investigation	YES
4100568	25045603	KF	2	carried out the radiochemical synthesis and radio-hplc metabolite analysis	carried out the radiochemical synthesis and radio-hplc metabolite analysis	Performed the experiments	Investigation	YES
4100568	25045603	MH	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4100568	25045603	MI	2	conceived of and contributed to the study design	conceived of and contributed to the study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4100568	25045603	MRZ	2	revised the manuscript|carried out the radiochemical synthesis and radio-hplc metabolite analysis	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4100568	25045603	MRZ	2	revised the manuscript|carried out the radiochemical synthesis and radio-hplc metabolite analysis	carried out the radiochemical synthesis and radio-hplc metabolite analysis	Performed the experiments	Investigation	YES
4100568	25045603	MT	2	carried out the radiochemical synthesis and radio-hplc metabolite analysis	carried out the radiochemical synthesis and radio-hplc metabolite analysis	Performed the experiments	Investigation	YES
4100568	25045603	SI	2	quantified the plasma unlabeled drug concentrations	quantified the plasma unlabeled drug concentrations	Performed the experiments	Investigation	YES
4100568	25045603	SO	2	conceived of and contributed to the study design|performed the experiments and acquired the pet data	conceived of and contributed to the study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4100568	25045603	SO	2	conceived of and contributed to the study design|performed the experiments and acquired the pet data	performed the experiments and acquired the pet data	Performed the experiments	Investigation	YES
4100568	25045603	TI	2	carried out the radiochemical synthesis and radio-hplc metabolite analysis	carried out the radiochemical synthesis and radio-hplc metabolite analysis	Performed the experiments	Investigation	YES
4100568	25045603	TM	2	conceived of and contributed to the study design|participated in interpretation of the data	conceived of and contributed to the study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4100568	25045603	TM	2	conceived of and contributed to the study design|participated in interpretation of the data	participated in interpretation of the data	Analyzed the data	Formal analysis	YES
4100568	25045603	TS	2	conceived of and contributed to the study design|supervised the study	conceived of and contributed to the study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4100568	25045603	TS	2	conceived of and contributed to the study design|supervised the study	supervised the study	-	Supervision	YES
4100568	25045603	YN	2	conceived of and contributed to the study design|performed the experiments and acquired the pet data|participated in interpretation of the data	conceived of and contributed to the study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4100568	25045603	YN	2	conceived of and contributed to the study design|performed the experiments and acquired the pet data|participated in interpretation of the data	performed the experiments and acquired the pet data	Performed the experiments	Investigation	YES
4100568	25045603	YN	2	conceived of and contributed to the study design|performed the experiments and acquired the pet data|participated in interpretation of the data	participated in interpretation of the data	Analyzed the data	Formal analysis	YES
4100568	25045603	YS	2	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
1790703	17299593	CC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1790703	17299593	CC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1790703	17299593	CC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1790703	17299593	CC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1790703	17299593	JR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1790703	17299593	JR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1790703	17299593	JR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1790703	17299593	JR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1790703	17299593	JS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1790703	17299593	JS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5461550	28589866	AMT	2	designed the computational work	designed the computational work	Conceived and designed the experiments	Formal analysis	YES
5461550	28589866	CDJ	2	designed the molecular experiments	designed the molecular experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5461550	28589866	JKT	2	designed the molecular experiments	designed the molecular experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5461550	28589866	MLP	2	designed the molecular experiments	designed the molecular experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5461550	28589866	S-HS	2	designed the computational work	designed the computational work	Conceived and designed the experiments	Formal analysis	YES
4607703	26347539	A.C.	2	crafted the figures	crafted the figures	-	Visualization	YES
4607703	26347539	A.M.	2	crafted the figures	crafted the figures	-	Visualization	YES
4607703	26347539	A.S.	2	set up the analytical instruments, performed the on-board measurements, collected the data and conducted quality control|collected and analysed sonar data|crafted the figures	set up the analytical instruments, performed the on-board measurements, collected the data and conducted quality control	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation|Methodology|Validation	YES
4607703	26347539	A.S.	2	set up the analytical instruments, performed the on-board measurements, collected the data and conducted quality control|collected and analysed sonar data|crafted the figures	collected and analysed sonar data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4607703	26347539	A.S.	2	set up the analytical instruments, performed the on-board measurements, collected the data and conducted quality control|collected and analysed sonar data|crafted the figures	crafted the figures	-	Visualization	YES
4607703	26347539	D.C.	2	set up the analytical instruments, performed the on-board measurements, collected the data and conducted quality control|collected and analysed sonar data|crafted the figures	set up the analytical instruments, performed the on-board measurements, collected the data and conducted quality control	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation|Methodology|Validation	YES
4607703	26347539	D.C.	2	set up the analytical instruments, performed the on-board measurements, collected the data and conducted quality control|collected and analysed sonar data|crafted the figures	collected and analysed sonar data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4607703	26347539	D.C.	2	set up the analytical instruments, performed the on-board measurements, collected the data and conducted quality control|collected and analysed sonar data|crafted the figures	crafted the figures	-	Visualization	YES
4607703	26347539	D.K.	2	set up the analytical instruments, performed the on-board measurements, collected the data and conducted quality control|crafted the figures	set up the analytical instruments, performed the on-board measurements, collected the data and conducted quality control	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation|Methodology|Validation	YES
4607703	26347539	D.K.	2	set up the analytical instruments, performed the on-board measurements, collected the data and conducted quality control|crafted the figures	crafted the figures	-	Visualization	YES
4607703	26347539	G.P.	2	performed data assimilation|crafted the figures	performed data assimilation	-	-	NO
4607703	26347539	G.P.	2	performed data assimilation|crafted the figures	crafted the figures	-	Visualization	YES
4607703	26347539	I.S.	2	designed the fieldwork|drafted the first manuscript	designed the fieldwork	Conceived and designed the experiments|Performed the experiments	Investigation	YES
4607703	26347539	I.S.	2	designed the fieldwork|drafted the first manuscript	drafted the first manuscript	Wrote the paper	Writing - Original Draft	YES
4607703	26347539	L.L.	2	designed the fieldwork	designed the fieldwork	Conceived and designed the experiments|Performed the experiments	Investigation	YES
4607703	26347539	N.S.	2	designed the fieldwork|crafted the figures|drafted the first manuscript	designed the fieldwork	Conceived and designed the experiments|Performed the experiments	Investigation	YES
4607703	26347539	N.S.	2	designed the fieldwork|crafted the figures|drafted the first manuscript	crafted the figures	-	Visualization	YES
4607703	26347539	N.S.	2	designed the fieldwork|crafted the figures|drafted the first manuscript	drafted the first manuscript	Wrote the paper	Writing - Original Draft	YES
4607703	26347539	O.D.	2	designed the fieldwork	designed the fieldwork	Conceived and designed the experiments|Performed the experiments	Investigation	YES
4607703	26347539	O.G.	2	drafted the first manuscript	drafted the first manuscript	Wrote the paper	Writing - Original Draft	YES
4607703	26347539	S.J.	2	designed the fieldwork	designed the fieldwork	Conceived and designed the experiments|Performed the experiments	Investigation	YES
4607703	26347539	V.Y.	2	collected and analysed sonar data	collected and analysed sonar data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4607703	26347539	Va.S.	2	designed the fieldwork	designed the fieldwork	Conceived and designed the experiments|Performed the experiments	Investigation	YES
4607703	26347539	Vl.S.	2	set up the analytical instruments, performed the on-board measurements, collected the data and conducted quality control|performed microbiological experiments	set up the analytical instruments, performed the on-board measurements, collected the data and conducted quality control	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation|Methodology|Validation	YES
4607703	26347539	Vl.S.	2	set up the analytical instruments, performed the on-board measurements, collected the data and conducted quality control|performed microbiological experiments	performed microbiological experiments	Performed the experiments	Investigation	YES
4607703	26347539	all authors	2	contributed to the final version	contributed to the final version	-	-	NO
6067082	30063290	ACT	2	contributed to design of the study, data analysis and interpretation, and editing of the article	contributed to design of the study, data analysis and interpretation, and editing of the article	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Review & Editing	YES
6067082	30063290	BTC	2	contributed to conceptualization and design of the study, acquisition of data, data analysis and interpretation, and drafting and editing of the article	contributed to conceptualization and design of the study, acquisition of data, data analysis and interpretation, and drafting and editing of the article	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
4553179	26351635	All authors	2	read and approved the final paper	read and approved the final paper	-	-	NO
4553179	26351635	Efstrathios Karagiannis	2	were, respectively, the sponsors project manager and the sponsors medical officer for the trial|wrote the first draft of the paper	were, respectively, the sponsors project manager and the sponsors medical officer for the trial	-	Project administration	YES
4553179	26351635	Efstrathios Karagiannis	2	were, respectively, the sponsors project manager and the sponsors medical officer for the trial|wrote the first draft of the paper	wrote the first draft of the paper	Wrote the paper	Writing - Original Draft	YES
4553179	26351635	Heinz-Gerd Richter	2	as consulting office-based physician were involved in the study design and conduct of the trial|contributed to the paper from the first draft stage onwards by reviewing, commenting, and critically revising where applicable	as consulting office-based physician were involved in the study design and conduct of the trial	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4553179	26351635	Heinz-Gerd Richter	2	as consulting office-based physician were involved in the study design and conduct of the trial|contributed to the paper from the first draft stage onwards by reviewing, commenting, and critically revising where applicable	contributed to the paper from the first draft stage onwards by reviewing, commenting, and critically revising where applicable	Wrote the paper	Writing - Original Draft	YES
4553179	26351635	Jochen Sieber	2	were, respectively, the sponsors project manager and the sponsors medical officer for the trial|as consulting office-based physician were involved in the study design and conduct of the trial|wrote the first draft of the paper	were, respectively, the sponsors project manager and the sponsors medical officer for the trial	-	Project administration	YES
4553179	26351635	Jochen Sieber	2	were, respectively, the sponsors project manager and the sponsors medical officer for the trial|as consulting office-based physician were involved in the study design and conduct of the trial|wrote the first draft of the paper	as consulting office-based physician were involved in the study design and conduct of the trial	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4553179	26351635	Jochen Sieber	2	were, respectively, the sponsors project manager and the sponsors medical officer for the trial|as consulting office-based physician were involved in the study design and conduct of the trial|wrote the first draft of the paper	wrote the first draft of the paper	Wrote the paper	Writing - Original Draft	YES
4553179	26351635	Ludger Klimek	2	contributed to the paper from the first draft stage onwards by reviewing, commenting, and critically revising where applicable	contributed to the paper from the first draft stage onwards by reviewing, commenting, and critically revising where applicable	Wrote the paper	Writing - Original Draft	YES
4553179	26351635	Meike Hadler	2	as consulting office-based physician were involved in the study design and conduct of the trial|wrote the first draft of the paper	as consulting office-based physician were involved in the study design and conduct of the trial	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4553179	26351635	Meike Hadler	2	as consulting office-based physician were involved in the study design and conduct of the trial|wrote the first draft of the paper	wrote the first draft of the paper	Wrote the paper	Writing - Original Draft	YES
4553179	26351635	Oliver Pfaar	2	contributed to the paper from the first draft stage onwards by reviewing, commenting, and critically revising where applicable|took overall responsibility for finalization and submission of the paper	contributed to the paper from the first draft stage onwards by reviewing, commenting, and critically revising where applicable	Wrote the paper	Writing - Original Draft	YES
4553179	26351635	Oliver Pfaar	2	contributed to the paper from the first draft stage onwards by reviewing, commenting, and critically revising where applicable|took overall responsibility for finalization and submission of the paper	took overall responsibility for finalization and submission of the paper	Wrote the paper	Writing - Review & Editing	YES
5641557	29075278	CL	PLoS52	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5641557	29075278	FB	PLoS52	generated the hop/sti1-rnai-line and antibody	generated the hop/sti1-rnai-line and antibody	Performed the experiments	Investigation	YES
5641557	29075278	H-PM	PLoS52	conceived and designed the experiments|generated the hop/sti1-rnai-line and antibody	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5641557	29075278	H-PM	PLoS52	conceived and designed the experiments|generated the hop/sti1-rnai-line and antibody	generated the hop/sti1-rnai-line and antibody	Performed the experiments	Investigation	YES
5641557	29075278	JH	PLoS52	measured extracted sa by hplc	measured extracted sa by hplc	Performed the experiments	Investigation	YES
5641557	29075278	US	PLoS52	conceived and designed the experiments|analyzed the data|wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5641557	29075278	US	PLoS52	conceived and designed the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5641557	29075278	US	PLoS52	conceived and designed the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4109699	24369816	AC	2	collected and processed imaging and blood sample data	collected and processed imaging and blood sample data	Performed the experiments|Analyzed the data	Data curation|Investigation|Visualization	YES
4109699	24369816	DLa	2	conceived the study design	conceived the study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4109699	24369816	DLi	2	performed the data analysis	performed the data analysis	Analyzed the data	Formal analysis	YES
4109699	24369816	JDF	2	conceived the study design|drafted the manuscript	conceived the study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4109699	24369816	JDF	2	conceived the study design|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4109699	24369816	PM	2	conceived the study design|collected and processed imaging and blood sample data	conceived the study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4109699	24369816	PM	2	conceived the study design|collected and processed imaging and blood sample data	collected and processed imaging and blood sample data	Performed the experiments|Analyzed the data	Data curation|Investigation|Visualization	YES
4109699	24369816	SLH	2	performed the data analysis|drafted the manuscript	performed the data analysis	Analyzed the data	Formal analysis	YES
4109699	24369816	SLH	2	performed the data analysis|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4410526	26124549	Akshay Anand	7	Conceptualised and designed the study	Conceptualised and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4410526	26124549	Keshav Thakur	7	Acquired data, conducted the experiment	Acquired data, conducted the experiment	Performed the experiments	Investigation	YES
4410526	26124549	Pawan Gupta	7	Collected the control sample	Collected the control sample	Performed the experiments	Investigation	YES
4410526	26124549	Sudesh Prabhakar	7	Provided the als patients	Provided the als patients	-	-	NO
4410526	26124549	Suresh Sharma	7	performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
4608030	26460115	A.T.	2	leading the development and analysis	leading the development and analysis	-	-	NO
4608030	26460115	All co-authors	2	gave approval for the work to be published	gave approval for the work to be published	-	-	NO
4608030	26460115	S.D.	2	was responsible for the initial conceptualization of this research|gave approval for the work to be published	was responsible for the initial conceptualization of this research	Conceived and designed the experiments	Conceptualization	YES
4608030	26460115	S.D.	2	was responsible for the initial conceptualization of this research|gave approval for the work to be published	gave approval for the work to be published	-	-	NO
4608030	26460115	W.B.	2	gave approval for the work to be published	gave approval for the work to be published	-	-	NO
4409378	25909444	AKG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409378	25909444	AKG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409378	25909444	AKG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409378	25909444	ANK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409378	25909444	ANK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409378	25909444	ANK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409378	25909444	BH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409378	25909444	MLR	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409378	25909444	TLM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409378	25909444	WCN	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4409378	25909444	WCN	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4129469	25136512	DP	2	contributed to the study concept and assisted in drafting the manuscript|is the owner of the patent of ns14490 which was used as reference compound and supported the blocking compound ns6740	contributed to the study concept and assisted in drafting the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4129469	25136512	DP	2	contributed to the study concept and assisted in drafting the manuscript|is the owner of the patent of ns14490 which was used as reference compound and supported the blocking compound ns6740	is the owner of the patent of ns14490 which was used as reference compound and supported the blocking compound ns6740	Performed the experiments	Investigation	YES
4129469	25136512	JS	2	contributed to the study concept and revised the manuscript critically	contributed to the study concept and revised the manuscript critically	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
4129469	25136512	MS	2	was responsible for the synthesis of precursor material and assisted in drafting the manuscript	was responsible for the synthesis of precursor material and assisted in drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
4129469	25136512	OS	2	supported the pet studies and revised the manuscript critically	supported the pet studies and revised the manuscript critically	Wrote the paper	Writing - Review & Editing	YES
4129469	25136512	PC	2	analysed the pet data concerning the imaging of a7 nicotinic acetylcholine receptors in the brain	analysed the pet data concerning the imaging of a7 nicotinic acetylcholine receptors in the brain	Analyzed the data	Formal analysis|Visualization	YES
4129469	25136512	PET	2	scans, performed the statistical analysis and critically revised the manuscript	scans, performed the statistical analysis and critically revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4129469	25136512	SR	2	was responsible for the synthesis of the radiotracer and the analysis of radiometabolites	was responsible for the synthesis of the radiotracer and the analysis of radiometabolites	-	-	NO
5461553	28589865	Both authors	2	wrote the manuscript, designed the experiments, and analyzed the data	wrote the manuscript, designed the experiments, and analyzed the data	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5461553	28589865	NA	2	also run the experiments and prepared the illustrations	also run the experiments and prepared the illustrations	Analyzed the data	Visualization	YES
3771439	24068887	Abbas Ghorbani	2	had contributed to data collection and analysis|also contributed to drafting the paper	had contributed to data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3771439	24068887	Abbas Ghorbani	2	had contributed to data collection and analysis|also contributed to drafting the paper	also contributed to drafting the paper	Wrote the paper	Writing - Original Draft	YES
3771439	24068887	Ali Gholamrezaei	2	had contributed to data collection and analysis|also contributed to drafting the paper	had contributed to data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3771439	24068887	Ali Gholamrezaei	2	had contributed to data collection and analysis|also contributed to drafting the paper	also contributed to drafting the paper	Wrote the paper	Writing - Original Draft	YES
3771439	24068887	Alireza Zandifar	2	had substantial contributions to conception and design of the study, analysis of the data, and drafting the paper	had substantial contributions to conception and design of the study, analysis of the data, and drafting the paper	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Methodology|Resources|Writing - Original Draft	YES
3771439	24068887	Behzad Zolfaghari	2	had contributed to data collection and analysis|also contributed to drafting the paper	had contributed to data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3771439	24068887	Behzad Zolfaghari	2	had contributed to data collection and analysis|also contributed to drafting the paper	also contributed to drafting the paper	Wrote the paper	Writing - Original Draft	YES
3771439	24068887	Faraidoon Haghdoost	2	had contributed to data collection and analysis|also contributed to drafting the paper	had contributed to data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3771439	24068887	Faraidoon Haghdoost	2	had contributed to data collection and analysis|also contributed to drafting the paper	also contributed to drafting the paper	Wrote the paper	Writing - Original Draft	YES
3771439	24068887	Fatemeh Asgari	2	had contributed to data collection and analysis|also contributed to drafting the paper	had contributed to data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3771439	24068887	Fatemeh Asgari	2	had contributed to data collection and analysis|also contributed to drafting the paper	also contributed to drafting the paper	Wrote the paper	Writing - Original Draft	YES
3771439	24068887	Mahboobeh Banihashemi	2	had contributed to data collection and analysis|also contributed to drafting the paper	had contributed to data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3771439	24068887	Mahboobeh Banihashemi	2	had contributed to data collection and analysis|also contributed to drafting the paper	also contributed to drafting the paper	Wrote the paper	Writing - Original Draft	YES
3771439	24068887	Mohammad Reza Najafi	2	had contributed to data collection and analysis|also contributed to drafting the paper	had contributed to data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3771439	24068887	Mohammad Reza Najafi	2	had contributed to data collection and analysis|also contributed to drafting the paper	also contributed to drafting the paper	Wrote the paper	Writing - Original Draft	YES
3771439	24068887	Mohammad Saadatnia	2	had substantial contributions to conception and design of the study, analysis of the data, and drafting the paper	had substantial contributions to conception and design of the study, analysis of the data, and drafting the paper	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Methodology|Resources|Writing - Original Draft	YES
3771439	24068887	Navid Manouchehri	2	had contributed to data collection and analysis|also contributed to drafting the paper	had contributed to data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3771439	24068887	Navid Manouchehri	2	had contributed to data collection and analysis|also contributed to drafting the paper	also contributed to drafting the paper	Wrote the paper	Writing - Original Draft	YES
3771439	24068887	Samaneh Sadat Masjedi	2	had contributed to data collection and analysis|also contributed to drafting the paper	had contributed to data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3771439	24068887	Samaneh Sadat Masjedi	2	had contributed to data collection and analysis|also contributed to drafting the paper	also contributed to drafting the paper	Wrote the paper	Writing - Original Draft	YES
3771439	24068887	Vahid Shaygannejad	2	had contributed to data collection and analysis|also contributed to drafting the paper	had contributed to data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3771439	24068887	Vahid Shaygannejad	2	had contributed to data collection and analysis|also contributed to drafting the paper	also contributed to drafting the paper	Wrote the paper	Writing - Original Draft	YES
1790860	17311088	AK	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1790860	17311088	AK	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1790860	17311088	DN	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1790860	17311088	FH	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1790860	17311088	JC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1790860	17311088	MD	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5641558	29075274	KC	2	co-wrote the manuscript	co-wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5641558	29075274	TV	2	designed the experimental approach|co-wrote the manuscript	designed the experimental approach	Conceived and designed the experiments	Methodology	YES
5641558	29075274	TV	2	designed the experimental approach|co-wrote the manuscript	co-wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6085595	30094952	AM	2	conducted study implementation and/or study oversight	conducted study implementation and/or study oversight	Performed the experiments	Investigation|Supervision	YES
6085595	30094952	CAT	2	designed the study|conducted study implementation and/or study oversight|developed the analytic approach and conducted the analyses	designed the study	Conceived and designed the experiments	Methodology	YES
6085595	30094952	CAT	2	designed the study|conducted study implementation and/or study oversight|developed the analytic approach and conducted the analyses	conducted study implementation and/or study oversight	Performed the experiments	Investigation|Supervision	YES
6085595	30094952	CAT	2	designed the study|conducted study implementation and/or study oversight|developed the analytic approach and conducted the analyses	developed the analytic approach and conducted the analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6085595	30094952	CW	2	developed the analytic approach and conducted the analyses	developed the analytic approach and conducted the analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6085595	30094952	EJA	2	designed the study|conducted study implementation and/or study oversight|developed the analytic approach and conducted the analyses	designed the study	Conceived and designed the experiments	Methodology	YES
6085595	30094952	EJA	2	designed the study|conducted study implementation and/or study oversight|developed the analytic approach and conducted the analyses	conducted study implementation and/or study oversight	Performed the experiments	Investigation|Supervision	YES
6085595	30094952	EJA	2	designed the study|conducted study implementation and/or study oversight|developed the analytic approach and conducted the analyses	developed the analytic approach and conducted the analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6085595	30094952	ER	2	designed the study|conducted study implementation and/or study oversight	designed the study	Conceived and designed the experiments	Methodology	YES
6085595	30094952	ER	2	designed the study|conducted study implementation and/or study oversight	conducted study implementation and/or study oversight	Performed the experiments	Investigation|Supervision	YES
6085595	30094952	KY	2	developed the analytic approach and conducted the analyses	developed the analytic approach and conducted the analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6085595	30094952	LP	2	conducted study implementation and/or study oversight	conducted study implementation and/or study oversight	Performed the experiments	Investigation|Supervision	YES
6085595	30094952	MM	2	designed the study|conducted study implementation and/or study oversight	designed the study	Conceived and designed the experiments	Methodology	YES
6085595	30094952	MM	2	designed the study|conducted study implementation and/or study oversight	conducted study implementation and/or study oversight	Performed the experiments	Investigation|Supervision	YES
6085595	30094952	MN	2	conducted study implementation and/or study oversight	conducted study implementation and/or study oversight	Performed the experiments	Investigation|Supervision	YES
6085595	30094952	NS	2	conducted study implementation and/or study oversight	conducted study implementation and/or study oversight	Performed the experiments	Investigation|Supervision	YES
6085595	30094952	SA	2	designed the study|conducted study implementation and/or study oversight	designed the study	Conceived and designed the experiments	Methodology	YES
6085595	30094952	SA	2	designed the study|conducted study implementation and/or study oversight	conducted study implementation and/or study oversight	Performed the experiments	Investigation|Supervision	YES
6085595	30094952	all authors	2	contributed to manuscript writing and review	contributed to manuscript writing and review	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4608031	26460109	J.P.	2	contributed to the original research idea and to conceptualizing the research design|all co-authors gave approval for the work to be published	contributed to the original research idea and to conceptualizing the research design	Conceived and designed the experiments	Conceptualization	YES
4608031	26460109	J.P.	2	contributed to the original research idea and to conceptualizing the research design|all co-authors gave approval for the work to be published	all co-authors gave approval for the work to be published	-	-	NO
4608031	26460109	P.M.F.	2	contributed to the original research idea and to conceptualizing the research design|all co-authors gave approval for the work to be published	contributed to the original research idea and to conceptualizing the research design	Conceived and designed the experiments	Conceptualization	YES
4608031	26460109	P.M.F.	2	contributed to the original research idea and to conceptualizing the research design|all co-authors gave approval for the work to be published	all co-authors gave approval for the work to be published	-	-	NO
4608031	26460109	S.D.	2	contributed to the original research idea and to conceptualizing the research design|all co-authors gave approval for the work to be published	contributed to the original research idea and to conceptualizing the research design	Conceived and designed the experiments	Conceptualization	YES
4608031	26460109	S.D.	2	contributed to the original research idea and to conceptualizing the research design|all co-authors gave approval for the work to be published	all co-authors gave approval for the work to be published	-	-	NO
4608031	26460109	S.L.	2	contributed to the original research idea and to conceptualizing the research design|was responsible for data collection and analysis	contributed to the original research idea and to conceptualizing the research design	Conceived and designed the experiments	Conceptualization	YES
4608031	26460109	S.L.	2	contributed to the original research idea and to conceptualizing the research design|was responsible for data collection and analysis	was responsible for data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4409379	25910071	AK	PLoS5	Wrote the paper|Read and approved the final manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409379	25910071	AK	PLoS5	Wrote the paper|Read and approved the final manuscript	Read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4409379	25910071	AZ	PLoS5	Made a substantial contribution to interpretation of data, drafting and carefully revising the manuscript for intellectual content|Read and approved the final manuscript	Made a substantial contribution to interpretation of data, drafting and carefully revising the manuscript for intellectual content	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft|Writing - Review & Editing	YES
4409379	25910071	AZ	PLoS5	Made a substantial contribution to interpretation of data, drafting and carefully revising the manuscript for intellectual content|Read and approved the final manuscript	Read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4409379	25910071	DT	PLoS5	Made a substantial contribution to interpretation of data, drafting and carefully revising the manuscript for intellectual content|Read and approved the final manuscript	Made a substantial contribution to interpretation of data, drafting and carefully revising the manuscript for intellectual content	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft|Writing - Review & Editing	YES
4409379	25910071	DT	PLoS5	Made a substantial contribution to interpretation of data, drafting and carefully revising the manuscript for intellectual content|Read and approved the final manuscript	Read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4409379	25910071	GZ	PLoS5	Wrote the paper|Read and approved the final manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409379	25910071	GZ	PLoS5	Wrote the paper|Read and approved the final manuscript	Read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4409379	25910071	HAA	PLoS5	Wrote the paper|Read and approved the final manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409379	25910071	HAA	PLoS5	Wrote the paper|Read and approved the final manuscript	Read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4409379	25910071	JMF	PLoS5	Made a substantial contribution to interpretation of data, drafting and carefully revising the manuscript for intellectual content|Read and approved the final manuscript	Made a substantial contribution to interpretation of data, drafting and carefully revising the manuscript for intellectual content	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft|Writing - Review & Editing	YES
4409379	25910071	JMF	PLoS5	Made a substantial contribution to interpretation of data, drafting and carefully revising the manuscript for intellectual content|Read and approved the final manuscript	Read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4409379	25910071	RZ	PLoS5	Wrote the paper|Read and approved the final manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409379	25910071	RZ	PLoS5	Wrote the paper|Read and approved the final manuscript	Read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4175513	24267032	AL	2	provided intellectual input and reviewed the manuscript	provided intellectual input and reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
4175513	24267032	BBB	2	selected the patient studies and performed the lesion delineation	selected the patient studies and performed the lesion delineation	Performed the experiments	Investigation	YES
4175513	24267032	FH	2	performed part of the data analysis and wrote part of the manuscript	performed part of the data analysis and wrote part of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4175513	24267032	GS	2	performed part of the data analysis	performed part of the data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4175513	24267032	JM	2	provided intellectual input and reviewed the manuscript	provided intellectual input and reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
4175513	24267032	JP	2	provided intellectual input and reviewed the manuscript	provided intellectual input and reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
4175513	24267032	LO	2	performed part of the data analysis	performed part of the data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4175513	24267032	SUR	2	performed part of the data analysis, and wrote part of the manuscript	performed part of the data analysis, and wrote part of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4410529	26124551	Ajay Prakash	7	Helped with pharmacotherapy portion of review	Helped with pharmacotherapy portion of review	-	-	NO
4410529	26124551	Bikash Medhi	7	Provided technical guidance and did proof reading	Provided technical guidance and did proof reading	-	Supervision	YES
4410529	26124551	Rakesh Ruhela	7	Concept preparation, literature search, review writing and diagram preparation	Concept preparation, literature search, review writing and diagram preparation	Conceived and designed the experiments|Wrote the paper	Conceptualization|Formal analysis	YES
5461558	28589864	AS	2	evaluated the performance of the pipeline on the experimental datasets	evaluated the performance of the pipeline on the experimental datasets	Performed the experiments	Investigation	YES
5461558	28589864	CT	2	designed and evaluated the performance of the maximal common substring approach	designed and evaluated the performance of the maximal common substring approach	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5461558	28589864	DSC	2	designed the study|designed and implemented the hamming and the identical sequences filter|designed and implemented the k-mer bloom filter|evaluated the performance of the pipeline on the experimental datasets|analysed all data|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5461558	28589864	DSC	2	designed the study|designed and implemented the hamming and the identical sequences filter|designed and implemented the k-mer bloom filter|evaluated the performance of the pipeline on the experimental datasets|analysed all data|wrote the manuscript	designed and implemented the hamming and the identical sequences filter	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5461558	28589864	DSC	2	designed the study|designed and implemented the hamming and the identical sequences filter|designed and implemented the k-mer bloom filter|evaluated the performance of the pipeline on the experimental datasets|analysed all data|wrote the manuscript	designed and implemented the k-mer bloom filter	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5461558	28589864	DSC	2	designed the study|designed and implemented the hamming and the identical sequences filter|designed and implemented the k-mer bloom filter|evaluated the performance of the pipeline on the experimental datasets|analysed all data|wrote the manuscript	evaluated the performance of the pipeline on the experimental datasets	Performed the experiments	Investigation	YES
5461558	28589864	DSC	2	designed the study|designed and implemented the hamming and the identical sequences filter|designed and implemented the k-mer bloom filter|evaluated the performance of the pipeline on the experimental datasets|analysed all data|wrote the manuscript	analysed all data	Analyzed the data	Formal analysis	YES
5461558	28589864	DSC	2	designed the study|designed and implemented the hamming and the identical sequences filter|designed and implemented the k-mer bloom filter|evaluated the performance of the pipeline on the experimental datasets|analysed all data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5461558	28589864	IR	2	designed the study|designed and implemented the hamming and the identical sequences filter|evaluated the performance of the pipeline on the experimental datasets|analysed all data|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5461558	28589864	IR	2	designed the study|designed and implemented the hamming and the identical sequences filter|evaluated the performance of the pipeline on the experimental datasets|analysed all data|wrote the manuscript	designed and implemented the hamming and the identical sequences filter	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5461558	28589864	IR	2	designed the study|designed and implemented the hamming and the identical sequences filter|evaluated the performance of the pipeline on the experimental datasets|analysed all data|wrote the manuscript	evaluated the performance of the pipeline on the experimental datasets	Performed the experiments	Investigation	YES
5461558	28589864	IR	2	designed the study|designed and implemented the hamming and the identical sequences filter|evaluated the performance of the pipeline on the experimental datasets|analysed all data|wrote the manuscript	analysed all data	Analyzed the data	Formal analysis	YES
5461558	28589864	IR	2	designed the study|designed and implemented the hamming and the identical sequences filter|evaluated the performance of the pipeline on the experimental datasets|analysed all data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5461558	28589864	JC	2	designed and evaluated the performance of the maximal common substring approach	designed and evaluated the performance of the maximal common substring approach	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5461558	28589864	SA	2	designed and evaluated the performance of the maximal common substring approach	designed and evaluated the performance of the maximal common substring approach	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5461558	28589864	SPC	2	designed and evaluated the performance of the maximal common substring approach	designed and evaluated the performance of the maximal common substring approach	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5461558	28589864	SS	2	designed and implemented hdist	designed and implemented hdist	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5461558	28589864	SVT	2	designed and evaluated the performance of the maximal common substring approach	designed and evaluated the performance of the maximal common substring approach	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5461558	28589864	YK	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5461558	28589864	YZ	2	designed and implemented the k-mer bloom filter	designed and implemented the k-mer bloom filter	Conceived and designed the experiments|Performed the experiments	Investigation	YES
4608033	26392620	Both authors	2	contributed equally to this study	contributed equally to this study	-	-	NO
1790862	17311089	EH	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1790862	17311089	EH	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1790862	17311089	JM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1790862	17311089	JM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1790862	17311089	JM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1790862	17311089	MS	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1790862	17311089	MS	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1790862	17311089	RB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1790862	17311089	RB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1790862	17311089	RB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1790862	17311089	RB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1790862	17311089	RL	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1790862	17311089	SE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1790862	17311089	SE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1790862	17311089	SE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1790862	17311089	SE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1790862	17311089	ZS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1790862	17311089	ZS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1790862	17311089	ZS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1790862	17311089	ZX	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5641559	29075273	DM	CRediT	Methodology|Resources|Supervision	Methodology	Performed the experiments	Methodology	YES
5641559	29075273	DM	CRediT	Methodology|Resources|Supervision	Resources	Contributed reagents/materials/analysis tools	Resources	YES
5641559	29075273	DM	CRediT	Methodology|Resources|Supervision	Supervision	-	Supervision	YES
5641559	29075273	FC	CRediT	Writing - review & editing	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
5641559	29075273	FR	CRediT	Methodology|Investigation	Methodology	Performed the experiments	Methodology	YES
5641559	29075273	FR	CRediT	Methodology|Investigation	Investigation	Performed the experiments	Investigation	YES
5641559	29075273	LN	CRediT	Methodology|Investigation|Writing - review & editing	Methodology	Performed the experiments	Methodology	YES
5641559	29075273	LN	CRediT	Methodology|Investigation|Writing - review & editing	Investigation	Performed the experiments	Investigation	YES
5641559	29075273	LN	CRediT	Methodology|Investigation|Writing - review & editing	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
5641559	29075273	LT	CRediT	Conceptualization|Methodology|Writing - original draft|Writing - review & editing|Funding acquisition|Supervision	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
5641559	29075273	LT	CRediT	Conceptualization|Methodology|Writing - original draft|Writing - review & editing|Funding acquisition|Supervision	Methodology	Performed the experiments	Methodology	YES
5641559	29075273	LT	CRediT	Conceptualization|Methodology|Writing - original draft|Writing - review & editing|Funding acquisition|Supervision	Writing - original draft	Wrote the paper	Writing - Original Draft	YES
5641559	29075273	LT	CRediT	Conceptualization|Methodology|Writing - original draft|Writing - review & editing|Funding acquisition|Supervision	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
5641559	29075273	LT	CRediT	Conceptualization|Methodology|Writing - original draft|Writing - review & editing|Funding acquisition|Supervision	Funding acquisition	-	Funding acquisition	YES
5641559	29075273	LT	CRediT	Conceptualization|Methodology|Writing - original draft|Writing - review & editing|Funding acquisition|Supervision	Supervision	-	Supervision	YES
5641559	29075273	MP	CRediT	Resources	Resources	Contributed reagents/materials/analysis tools	Resources	YES
5641559	29075273	NB	CRediT	Methodology|Investigation|Writing - original draft|Writing - review & editing	Methodology	Performed the experiments	Methodology	YES
5641559	29075273	NB	CRediT	Methodology|Investigation|Writing - original draft|Writing - review & editing	Investigation	Performed the experiments	Investigation	YES
5641559	29075273	NB	CRediT	Methodology|Investigation|Writing - original draft|Writing - review & editing	Writing - original draft	Wrote the paper	Writing - Original Draft	YES
5641559	29075273	NB	CRediT	Methodology|Investigation|Writing - original draft|Writing - review & editing	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
5641559	29075273	OM	CRediT	Resources	Resources	Contributed reagents/materials/analysis tools	Resources	YES
5641559	29075273	SQ	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
5641559	29075273	US	CRediT	Investigation|Writing - review & editing	Investigation	Performed the experiments	Investigation	YES
5641559	29075273	US	CRediT	Investigation|Writing - review & editing	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
6088247	30101434	All authors	2	critically reviewed the manuscript and approved the final version|had full access to all of the data in the study and can take responsibility for the integrity of the data and the accuracy of the data analysis and believe that the manuscript represents honest work	critically reviewed the manuscript and approved the final version	Wrote the paper	Writing - Review & Editing	YES
6088247	30101434	All authors	2	critically reviewed the manuscript and approved the final version|had full access to all of the data in the study and can take responsibility for the integrity of the data and the accuracy of the data analysis and believe that the manuscript represents honest work	had full access to all of the data in the study and can take responsibility for the integrity of the data and the accuracy of the data analysis and believe that the manuscript represents honest work	Analyzed the data	Data curation|Formal analysis	YES
6088247	30101434	CJLMM	2	are principal investigators of the study|have set up the trial|were involved in data collection|drafted the manuscript|affirms that the manuscript is an honest, accurate and transparent account of the study being reported	are principal investigators of the study	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
6088247	30101434	CJLMM	2	are principal investigators of the study|have set up the trial|were involved in data collection|drafted the manuscript|affirms that the manuscript is an honest, accurate and transparent account of the study being reported	have set up the trial	Performed the experiments	Methodology	YES
6088247	30101434	CJLMM	2	are principal investigators of the study|have set up the trial|were involved in data collection|drafted the manuscript|affirms that the manuscript is an honest, accurate and transparent account of the study being reported	were involved in data collection	Performed the experiments	Investigation	YES
6088247	30101434	CJLMM	2	are principal investigators of the study|have set up the trial|were involved in data collection|drafted the manuscript|affirms that the manuscript is an honest, accurate and transparent account of the study being reported	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
6088247	30101434	CJLMM	2	are principal investigators of the study|have set up the trial|were involved in data collection|drafted the manuscript|affirms that the manuscript is an honest, accurate and transparent account of the study being reported	affirms that the manuscript is an honest, accurate and transparent account of the study being reported	Analyzed the data	Data curation	YES
6088247	30101434	DAMH	2	were involved in data collection|drafted the manuscript	were involved in data collection	Performed the experiments	Investigation	YES
6088247	30101434	DAMH	2	were involved in data collection|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
6088247	30101434	GD	2	are principal investigators of the study|have set up the trial|were involved in data collection	are principal investigators of the study	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
6088247	30101434	GD	2	are principal investigators of the study|have set up the trial|were involved in data collection	have set up the trial	Performed the experiments	Methodology	YES
6088247	30101434	GD	2	are principal investigators of the study|have set up the trial|were involved in data collection	were involved in data collection	Performed the experiments	Investigation	YES
6088247	30101434	KLR	2	were involved in data collection	were involved in data collection	Performed the experiments	Investigation	YES
6088247	30101434	MZ	2	have set up the trial|were involved in data collection|managed the database|drafted the manuscript	have set up the trial	Performed the experiments	Methodology	YES
6088247	30101434	MZ	2	have set up the trial|were involved in data collection|managed the database|drafted the manuscript	were involved in data collection	Performed the experiments	Investigation	YES
6088247	30101434	MZ	2	have set up the trial|were involved in data collection|managed the database|drafted the manuscript	managed the database	Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Software	YES
6088247	30101434	MZ	2	have set up the trial|were involved in data collection|managed the database|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
6088247	30101434	PJF	2	have set up the trial	have set up the trial	Performed the experiments	Methodology	YES
6088247	30101434	PJFS	2	were involved in data collection	were involved in data collection	Performed the experiments	Investigation	YES
6088247	30101434	PWN	2	performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
6088247	30101434	RDMS	2	were involved in data collection|drafted the manuscript	were involved in data collection	Performed the experiments	Investigation	YES
6088247	30101434	RDMS	2	were involved in data collection|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
6088247	30101434	WV	2	were involved in data collection	were involved in data collection	Performed the experiments	Investigation	YES
6088247	30101434	WWK	2	have set up the trial|were involved in data collection|performed the statistical analysis|managed the database|drafted the manuscript	have set up the trial	Performed the experiments	Methodology	YES
6088247	30101434	WWK	2	have set up the trial|were involved in data collection|performed the statistical analysis|managed the database|drafted the manuscript	were involved in data collection	Performed the experiments	Investigation	YES
6088247	30101434	WWK	2	have set up the trial|were involved in data collection|performed the statistical analysis|managed the database|drafted the manuscript	performed the statistical analysis	Analyzed the data	Formal analysis	YES
6088247	30101434	WWK	2	have set up the trial|were involved in data collection|performed the statistical analysis|managed the database|drafted the manuscript	managed the database	Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Software	YES
6088247	30101434	WWK	2	have set up the trial|were involved in data collection|performed the statistical analysis|managed the database|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4176481	24238262	IH	2	accounts for conception of the study, planning of the experiments and revision of the manuscript	accounts for conception of the study, planning of the experiments and revision of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
4176481	24238262	MB	2	were in charge of the peptide sequence conception and preliminary peptide characterization as well as in evaluation of the manuscript	were in charge of the peptide sequence conception and preliminary peptide characterization as well as in evaluation of the manuscript	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
4176481	24238262	PC	2	is the inventor of the near-infrared fluorescence dye used in this study and accounted for customization of the dye construct, experiments concerning characterization of dy-754 and revision of the manuscript	is the inventor of the near-infrared fluorescence dye used in this study and accounted for customization of the dye construct, experiments concerning characterization of dy-754 and revision of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4176481	24238262	RM	2	were in charge of the peptide sequence conception and preliminary peptide characterization as well as in evaluation of the manuscript	were in charge of the peptide sequence conception and preliminary peptide characterization as well as in evaluation of the manuscript	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
4176481	24238262	SK	2	conducted the main parts of the experimental work presented in this manuscript, participated in study design, planned the presented experiments and wrote the manuscript	conducted the main parts of the experimental work presented in this manuscript, participated in study design, planned the presented experiments and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Writing - Original Draft	YES
4409380	25909362	GJM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409380	25909362	GJM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409380	25909362	GJM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409380	25909362	HJH	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409380	25909362	HJH	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409380	25909362	HJH	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409380	25909362	JH	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409380	25909362	JH	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409380	25909362	JO	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409380	25909362	JO	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409380	25909362	MV	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409380	25909362	MV	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409380	25909362	MV	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409380	25909362	PD	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409380	25909362	PD	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409380	25909362	SB	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409380	25909362	SB	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4176482	24274579	CL	2	recruited the subjects, acquired the image and blood data and participated in the data analysis and the design, coordination, and writing of the manuscript	recruited the subjects, acquired the image and blood data and participated in the data analysis and the design, coordination, and writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Project administration|Visualization|Writing - Original Draft	YES
4176482	24274579	CT	2	recruited the subjects, acquired the image and blood data and participated in the data analysis and the design, coordination, and writing of the manuscript	recruited the subjects, acquired the image and blood data and participated in the data analysis and the design, coordination, and writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Project administration|Visualization|Writing - Original Draft	YES
4176482	24274579	DR	2	recruited the subjects, acquired the image and blood data and participated in the data analysis and the design, coordination, and writing of the manuscript	recruited the subjects, acquired the image and blood data and participated in the data analysis and the design, coordination, and writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Project administration|Visualization|Writing - Original Draft	YES
4176482	24274579	JLM	2	recruited the subjects, acquired the image and blood data and participated in the data analysis and the design, coordination, and writing of the manuscript	recruited the subjects, acquired the image and blood data and participated in the data analysis and the design, coordination, and writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Project administration|Visualization|Writing - Original Draft	YES
4176482	24274579	MB	2	recruited the subjects, acquired the image and blood data and participated in the data analysis and the design, coordination, and writing of the manuscript	recruited the subjects, acquired the image and blood data and participated in the data analysis and the design, coordination, and writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Project administration|Visualization|Writing - Original Draft	YES
4176482	24274579	PZF	2	conceived of the study, performed the image analyses and statistical comparisons, and drafted the manuscript	conceived of the study, performed the image analyses and statistical comparisons, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Visualization|Writing - Original Draft	YES
1790863	17299597	JU	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1790863	17299597	JU	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1790863	17299597	LC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1790863	17299597	LC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1790863	17299597	LC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1790863	17299597	OS	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1790863	17299597	OS	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1790863	17299597	OS	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1790863	17299597	OT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1790863	17299597	OT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1790863	17299597	OT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1790863	17299597	OT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4410531	26124552	Iqbal Dar Samia	7	Helped in reviewing the work	Helped in reviewing the work	-	-	NO
4410531	26124552	Ishrat Hussain Dar	7	Helped in reviewing the work	Helped in reviewing the work	-	-	NO
4410531	26124552	M Zunga	7	author	author	-	-	NO
4410531	26124552	Mohamed Ashraf	7	Helped in reviewing the work	Helped in reviewing the work	-	-	NO
4410531	26124552	Pervaiz Omar Farooq	7	Co-author	Co-author	-	-	NO
4410531	26124552	Rashid Abdul Qayoom	7	Helped in reviewing the work	Helped in reviewing the work	-	-	NO
4410531	26124552	Rather Javaid Basu	7	Helped in reviewing the work	Helped in reviewing the work	-	-	NO
5641568	29075279	MA	2	wrote, revised, and approved this manuscript	wrote, revised, and approved this manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5641568	29075279	N-SL	2	wrote, revised, and approved this manuscript	wrote, revised, and approved this manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4608034	26392615	All authors	2	gave final approval for publication	gave final approval for publication	-	-	NO
4608034	26392615	C.B.H.	2	assisted in drafting the manuscript	assisted in drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
4608034	26392615	F.L.	2	carried out the majority of the simulations, produced the graphics and drafted the manuscript	carried out the majority of the simulations, produced the graphics and drafted the manuscript	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4608034	26392615	G.P.	2	implemented the green function method, conducted the dipole source simulation and assisted in drafting the manuscript	implemented the green function method, conducted the dipole source simulation and assisted in drafting the manuscript	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4608034	26392615	J.K.	2	conducted the voellmy landslide simulation and assisted in drafting the manuscript	conducted the voellmy landslide simulation and assisted in drafting the manuscript	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4608034	26392615	S.G.	2	assisted in drafting the manuscript	assisted in drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
5461559	28589860	AZ	2	coordinate the project and provide the significant advice on the method design	coordinate the project and provide the significant advice on the method design	Conceived and designed the experiments|Performed the experiments	Methodology|Project administration	YES
5461559	28589860	NY	2	performs the experiments and the implementation	performs the experiments and the implementation	Performed the experiments	Investigation	YES
5461559	28589860	XG	2	does the literature review and tests	does the literature review and tests	-	Formal analysis	YES
5461559	28589860	YP	2	coordinate the project and provide the significant advice on the method design	coordinate the project and provide the significant advice on the method design	Conceived and designed the experiments|Performed the experiments	Methodology|Project administration	YES
4409381	25910190	BW	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409381	25910190	BW	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409381	25910190	MF	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409381	25910190	MF	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409381	25910190	SM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409381	25910190	SM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409381	25910190	SM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409381	25910190	ZK	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
6088248	30101439	BM	2	were involved in data collection|were involved in data interpretation and presentation of results	were involved in data collection	Performed the experiments	Investigation	YES
6088248	30101439	BM	2	were involved in data collection|were involved in data interpretation and presentation of results	were involved in data interpretation and presentation of results	Analyzed the data	Formal analysis	YES
6088248	30101439	CD	2	were involved in data collection|were involved in data interpretation and presentation of results	were involved in data collection	Performed the experiments	Investigation	YES
6088248	30101439	CD	2	were involved in data collection|were involved in data interpretation and presentation of results	were involved in data interpretation and presentation of results	Analyzed the data	Formal analysis	YES
6088248	30101439	CH	2	were involved in data collection|were involved in data interpretation and presentation of results	were involved in data collection	Performed the experiments	Investigation	YES
6088248	30101439	CH	2	were involved in data collection|were involved in data interpretation and presentation of results	were involved in data interpretation and presentation of results	Analyzed the data	Formal analysis	YES
6088248	30101439	HS	2	were involved in data interpretation and presentation of results	were involved in data interpretation and presentation of results	Analyzed the data	Formal analysis	YES
6088248	30101439	JS	2	were involved in data interpretation and presentation of results	were involved in data interpretation and presentation of results	Analyzed the data	Formal analysis	YES
6088248	30101439	KB	2	were involved in data collection|were involved in data interpretation and presentation of results	were involved in data collection	Performed the experiments	Investigation	YES
6088248	30101439	KB	2	were involved in data collection|were involved in data interpretation and presentation of results	were involved in data interpretation and presentation of results	Analyzed the data	Formal analysis	YES
6088248	30101439	LM	2	were involved in data interpretation and presentation of results	were involved in data interpretation and presentation of results	Analyzed the data	Formal analysis	YES
6088248	30101439	LR	2	were involved in data interpretation and presentation of results	were involved in data interpretation and presentation of results	Analyzed the data	Formal analysis	YES
6088248	30101439	MM	2	were involved in data collection|were involved in data interpretation and presentation of results	were involved in data collection	Performed the experiments	Investigation	YES
6088248	30101439	MM	2	were involved in data collection|were involved in data interpretation and presentation of results	were involved in data interpretation and presentation of results	Analyzed the data	Formal analysis	YES
6088248	30101439	NRH	2	were involved in data interpretation and presentation of results	were involved in data interpretation and presentation of results	Analyzed the data	Formal analysis	YES
6088248	30101439	SLH	2	were involved in data interpretation and presentation of results	were involved in data interpretation and presentation of results	Analyzed the data	Formal analysis	YES
4205473	25386390	AB	2	participated in the design of the study and in the analysis and interpretation of data, and drafted the manuscript	participated in the design of the study and in the analysis and interpretation of data, and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4205473	25386390	ET	2	participated in the design of the study and in the analysis and interpretation of data, and drafted the manuscript	participated in the design of the study and in the analysis and interpretation of data, and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4205473	25386390	LE	2	participated in the design of the study and in the analysis and interpretation of data, and drafted the manuscript	participated in the design of the study and in the analysis and interpretation of data, and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4205473	25386390	MO	2	carried out the statistical analysis of the data	carried out the statistical analysis of the data	Analyzed the data	Formal analysis	YES
4205473	25386390	MR	2	participated in the design of the study and in the analysis and interpretation of data, and drafted the manuscript	participated in the design of the study and in the analysis and interpretation of data, and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4205473	25386390	PW	2	participated in the design of the study and in the analysis and interpretation of data, and drafted the manuscript	participated in the design of the study and in the analysis and interpretation of data, and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4205473	25386390	RK	2	participated in the design of the study and in the analysis and interpretation of data	participated in the design of the study and in the analysis and interpretation of data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5641574	29075282	DY	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5641574	29075282	FY	2	provided input in experiments	provided input in experiments	-	-	NO
5641574	29075282	HL	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5641574	29075282	JD	2	provided input in experiments	provided input in experiments	-	-	NO
5641574	29075282	JW	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5641574	29075282	LW	2	provided input in experiments	provided input in experiments	-	-	NO
5641574	29075282	PZ	2	provided input in experiments	provided input in experiments	-	-	NO
5641574	29075282	YY	2	provided input in experiments	provided input in experiments	-	-	NO
5641574	29075282	ZC	2	conducted the experiments, including phenotypic data evaluation and gwas analysis|wrote this manuscript	conducted the experiments, including phenotypic data evaluation and gwas analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5641574	29075282	ZC	2	conducted the experiments, including phenotypic data evaluation and gwas analysis|wrote this manuscript	wrote this manuscript	Wrote the paper	Writing - Original Draft	YES
4409382	25909186	BHS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409382	25909186	BHS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409382	25909186	BHS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409382	25909186	DY	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409382	25909186	JF	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409382	25909186	RCK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409382	25909186	RCK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409382	25909186	RCK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409382	25909186	RCK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409382	25909186	WYC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409382	25909186	WYC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409382	25909186	WYC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1790865	17311090	AB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1790865	17311090	CG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1790865	17311090	DM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1790865	17311090	DM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1790865	17311090	DM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1790865	17311090	DM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1790865	17311090	EL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1790865	17311090	EL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1790865	17311090	EL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1790865	17311090	EL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1790865	17311090	EL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1790865	17311090	JV	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1790865	17311090	MA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1790865	17311090	MA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1790865	17311090	MA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1790865	17311090	MA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1790865	17311090	ML	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1790865	17311090	ND	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1790865	17311090	SB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1790865	17311090	SB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1790865	17311090	SB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1790865	17311090	SB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4410533	26124544	A Mahadule	7	Collection of data, statistical analysis and drafting of article, Pravin	Collection of data, statistical analysis and drafting of article, Pravin	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4410533	26124544	S Jadhao	7	Design of study and statistical analysis, Mrunal	Design of study and statistical analysis, Mrunal	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
4410533	26124544	S Phatak	7	Raising the article to intellectual level	Raising the article to intellectual level	-	-	NO
6111144	30152004	A.M.	PLoS52	designed the research study|wrote the manuscript	designed the research study	Conceived and designed the experiments	Methodology	YES
6111144	30152004	A.M.	PLoS52	designed the research study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6111144	30152004	A.v.d.S.	PLoS52	designed the research study|wrote the manuscript	designed the research study	Conceived and designed the experiments	Methodology	YES
6111144	30152004	A.v.d.S.	PLoS52	designed the research study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6111144	30152004	E.K.	PLoS52	designed the research study|conducted the research|coordinated and managed data collection during the study|analysed the data|wrote the manuscript	designed the research study	Conceived and designed the experiments	Methodology	YES
6111144	30152004	E.K.	PLoS52	designed the research study|conducted the research|coordinated and managed data collection during the study|analysed the data|wrote the manuscript	conducted the research	Performed the experiments	Investigation	YES
6111144	30152004	E.K.	PLoS52	designed the research study|conducted the research|coordinated and managed data collection during the study|analysed the data|wrote the manuscript	coordinated and managed data collection during the study	Performed the experiments|Analyzed the data	Data curation|Investigation|Project administration	YES
6111144	30152004	E.K.	PLoS52	designed the research study|conducted the research|coordinated and managed data collection during the study|analysed the data|wrote the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
6111144	30152004	E.K.	PLoS52	designed the research study|conducted the research|coordinated and managed data collection during the study|analysed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6111144	30152004	E.M.	PLoS52	designed the research study|wrote the manuscript	designed the research study	Conceived and designed the experiments	Methodology	YES
6111144	30152004	E.M.	PLoS52	designed the research study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6111144	30152004	K.M.	PLoS52	coordinated and managed data collection during the study	coordinated and managed data collection during the study	Performed the experiments|Analyzed the data	Data curation|Investigation|Project administration	YES
6111144	30152004	L.-G.B.	PLoS52	designed the research study	designed the research study	Conceived and designed the experiments	Methodology	YES
6111144	30152004	M.A.	PLoS52	designed the research study|wrote the manuscript	designed the research study	Conceived and designed the experiments	Methodology	YES
6111144	30152004	M.A.	PLoS52	designed the research study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6111144	30152004	M.K.S.-Q.	PLoS52	coordinated and managed data collection during the study|analysed the data	coordinated and managed data collection during the study	Performed the experiments|Analyzed the data	Data curation|Investigation|Project administration	YES
6111144	30152004	M.K.S.-Q.	PLoS52	coordinated and managed data collection during the study|analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
6111144	30152004	S.N.	PLoS52	conducted the research|coordinated and managed data collection during the study	conducted the research	Performed the experiments	Investigation	YES
6111144	30152004	S.N.	PLoS52	conducted the research|coordinated and managed data collection during the study	coordinated and managed data collection during the study	Performed the experiments|Analyzed the data	Data curation|Investigation|Project administration	YES
6111144	30152004	T.M.	PLoS52	conducted the research|coordinated and managed data collection during the study	conducted the research	Performed the experiments	Investigation	YES
6111144	30152004	T.M.	PLoS52	conducted the research|coordinated and managed data collection during the study	coordinated and managed data collection during the study	Performed the experiments|Analyzed the data	Data curation|Investigation|Project administration	YES
4608035	26392619	Both authors	2	gave final approval for publication	gave final approval for publication	-	-	NO
4608035	26392619	C.B.P.	2	analysed the field data, coordinated the study and drafted the manuscript	analysed the field data, coordinated the study and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Project administration|Writing - Original Draft	YES
4608035	26392619	E.M.S.W.	2	undertook the numerical simulations and helped draft the manuscript	undertook the numerical simulations and helped draft the manuscript	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4209452	25386389	AB	2	designed the phantom and in vivo study and revised the manuscript|carried out the phantom and in vivo experiments	designed the phantom and in vivo study and revised the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
4209452	25386389	AB	2	designed the phantom and in vivo study and revised the manuscript|carried out the phantom and in vivo experiments	carried out the phantom and in vivo experiments	Performed the experiments	Investigation	YES
4209452	25386389	FJB	2	had the initial idea for this multimodal imaging platform, made the initial design of the optical module, participated in the study design, and revised the manuscript	had the initial idea for this multimodal imaging platform, made the initial design of the optical module, participated in the study design, and revised the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Methodology|Visualization|Writing - Review & Editing	YES
4209452	25386389	FWBvL	2	designed the phantom and in vivo study and revised the manuscript	designed the phantom and in vivo study and revised the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
4209452	25386389	LJ	2	prepared the dye for the in vivo study and revised the manuscript	prepared the dye for the in vivo study and revised the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
4209452	25386389	MNvO	2	integrated the optical module with the u-spect-ii scanner, added fluorescence imaging, acquired the images of the phantom and in vivo study, analyzed the results, and wrote initial versions of the manuscript	integrated the optical module with the u-spect-ii scanner, added fluorescence imaging, acquired the images of the phantom and in vivo study, analyzed the results, and wrote initial versions of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Visualization|Writing - Original Draft	YES
4209452	25386389	RK	2	integrated the optical module with the u-spect-ii scanner, added fluorescence imaging, acquired the images of the phantom and in vivo study, analyzed the results, and wrote initial versions of the manuscript	integrated the optical module with the u-spect-ii scanner, added fluorescence imaging, acquired the images of the phantom and in vivo study, analyzed the results, and wrote initial versions of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Visualization|Writing - Original Draft	YES
4209452	25386389	TB	2	designed the phantom and in vivo study and revised the manuscript|carried out the phantom and in vivo experiments	designed the phantom and in vivo study and revised the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
4209452	25386389	TB	2	designed the phantom and in vivo study and revised the manuscript|carried out the phantom and in vivo experiments	carried out the phantom and in vivo experiments	Performed the experiments	Investigation	YES
4209452	25386389	WAM	2	co-designed the optical module for bioluminescence imaging, carried out initial experiments, and revised the manuscript	co-designed the optical module for bioluminescence imaging, carried out initial experiments, and revised the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Investigation|Methodology|Visualization|Writing - Review & Editing	YES
5461714	28587590	AM	2	established the rna seq analysis pipeline, prepared the rna seq data for the analysis and validated the results of functional enrichment	established the rna seq analysis pipeline, prepared the rna seq data for the analysis and validated the results of functional enrichment	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Validation	YES
5461714	28587590	CM	2	were involved in the manuscript preparation	were involved in the manuscript preparation	Wrote the paper	Writing - Original Draft	YES
5461714	28587590	GD	2	were involved in the manuscript preparation	were involved in the manuscript preparation	Wrote the paper	Writing - Original Draft	YES
5461714	28587590	LV	2	designed and supervised the project and was involved in the manuscript preparation	designed and supervised the project and was involved in the manuscript preparation	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Original Draft	YES
5461714	28587590	NLT	2	was responsible for generating raw rna seq data	was responsible for generating raw rna seq data	Performed the experiments	Investigation	YES
5461714	28587590	NN	2	was deeply involved in sample preparation, hybridization of the microarrays and other laboratory work	was deeply involved in sample preparation, hybridization of the microarrays and other laboratory work	Performed the experiments	Investigation	YES
5461714	28587590	PB	2	collected, controlled and provided the samples	collected, controlled and provided the samples	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5461714	28587590	PVN	2	drafted the manuscript and was responsible for statistics and analysis of gene expression data	drafted the manuscript and was responsible for statistics and analysis of gene expression data	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5461714	28587590	TK	2	established pipelines for splicing analysis in microarrays and rna seq data sets|was responsible for the analysis of alternative splicing	established pipelines for splicing analysis in microarrays and rna seq data sets	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5461714	28587590	TK	2	established pipelines for splicing analysis in microarrays and rna seq data sets|was responsible for the analysis of alternative splicing	was responsible for the analysis of alternative splicing	-	-	NO
4555360	26357658	Alexander Pfeil	4	Study idea was by|Data acquisition was by|Image analysis was by|Statistical analysis was by|Literature search was by|Paper writing was by	Study idea was by	Conceived and designed the experiments	Conceptualization	YES
4555360	26357658	Alexander Pfeil	4	Study idea was by|Data acquisition was by|Image analysis was by|Statistical analysis was by|Literature search was by|Paper writing was by	Data acquisition was by	Performed the experiments	Investigation	YES
4555360	26357658	Alexander Pfeil	4	Study idea was by|Data acquisition was by|Image analysis was by|Statistical analysis was by|Literature search was by|Paper writing was by	Image analysis was by	Analyzed the data	Visualization	YES
4555360	26357658	Alexander Pfeil	4	Study idea was by|Data acquisition was by|Image analysis was by|Statistical analysis was by|Literature search was by|Paper writing was by	Statistical analysis was by	Analyzed the data	Formal analysis	YES
4555360	26357658	Alexander Pfeil	4	Study idea was by|Data acquisition was by|Image analysis was by|Statistical analysis was by|Literature search was by|Paper writing was by	Literature search was by	-	Formal analysis	YES
4555360	26357658	Alexander Pfeil	4	Study idea was by|Data acquisition was by|Image analysis was by|Statistical analysis was by|Literature search was by|Paper writing was by	Paper writing was by	Wrote the paper	-	YES
4555360	26357658	Andreas Hansch	4	Literature search was by	Literature search was by	-	Formal analysis	YES
4555360	26357658	Christian Jung	4	Data acquisition was by|Paper editing was by	Data acquisition was by	Performed the experiments	Investigation	YES
4555360	26357658	Christian Jung	4	Data acquisition was by|Paper editing was by	Paper editing was by	Wrote the paper	Writing - Review & Editing	YES
4555360	26357658	Diane M. Renz	4	Statistical analysis was by|Literature search was by	Statistical analysis was by	Analyzed the data	Formal analysis	YES
4555360	26357658	Diane M. Renz	4	Statistical analysis was by|Literature search was by	Literature search was by	-	Formal analysis	YES
4555360	26357658	Gunter Wolf	4	Study idea was by|Paper writing was by	Study idea was by	Conceived and designed the experiments	Conceptualization	YES
4555360	26357658	Gunter Wolf	4	Study idea was by|Paper writing was by	Paper writing was by	Wrote the paper	-	YES
4555360	26357658	Joachim Bottcher	4	Image analysis was by|Paper writing was by	Image analysis was by	Analyzed the data	Visualization	YES
4555360	26357658	Joachim Bottcher	4	Image analysis was by|Paper writing was by	Paper writing was by	Wrote the paper	-	YES
4555360	26357658	Karl F. Drummer	4	Data acquisition was by|Image analysis was by	Data acquisition was by	Performed the experiments	Investigation	YES
4555360	26357658	Karl F. Drummer	4	Data acquisition was by|Image analysis was by	Image analysis was by	Analyzed the data	Visualization	YES
4555360	26357658	Marcus Franz	4	Data acquisition was by|Paper editing was by	Data acquisition was by	Performed the experiments	Investigation	YES
4555360	26357658	Marcus Franz	4	Data acquisition was by|Paper editing was by	Paper editing was by	Wrote the paper	Writing - Review & Editing	YES
4555360	26357658	Peter Oelzner	4	Study idea was by|Paper writing was by	Study idea was by	Conceived and designed the experiments	Conceptualization	YES
4555360	26357658	Peter Oelzner	4	Study idea was by|Paper writing was by	Paper writing was by	Wrote the paper	-	YES
4480251	26130911	Ashish Aggarwal	7	Data collection, preparation of manuscript, Manoj	Data collection, preparation of manuscript, Manoj	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4480251	26130911	K Tewari	7	Critical review of manuscript, Suresh	Critical review of manuscript, Suresh	Wrote the paper	Writing - Review & Editing	YES
4480251	26130911	N Mathuriya	7	Interpretation and review of radiology	Interpretation and review of radiology	Analyzed the data	Formal analysis	YES
4480251	26130911	Vivek Gupta	7	Interpretation and review of radiology	Interpretation and review of radiology	Analyzed the data	Formal analysis	YES
4233307	25411652	DRO	2	carried out the data analysis, statistical analysis, and table and figure preparation|was primarily responsible for the preparation of the manuscript and multiple revisions	carried out the data analysis, statistical analysis, and table and figure preparation	Analyzed the data	Formal analysis|Visualization	YES
4233307	25411652	DRO	2	carried out the data analysis, statistical analysis, and table and figure preparation|was primarily responsible for the preparation of the manuscript and multiple revisions	was primarily responsible for the preparation of the manuscript and multiple revisions	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4233307	25411652	GJ	2	were responsible for the study design and experimental protocols|assisted dro in the preparation of the manuscript	were responsible for the study design and experimental protocols	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4233307	25411652	GJ	2	were responsible for the study design and experimental protocols|assisted dro in the preparation of the manuscript	assisted dro in the preparation of the manuscript	Wrote the paper	Writing - Original Draft	YES
4233307	25411652	RDO	2	were responsible for the study design and experimental protocols|assisted dro in the preparation of the manuscript	were responsible for the study design and experimental protocols	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4233307	25411652	RDO	2	were responsible for the study design and experimental protocols|assisted dro in the preparation of the manuscript	assisted dro in the preparation of the manuscript	Wrote the paper	Writing - Original Draft	YES
4409383	25910231	AH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409383	25910231	ARA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409383	25910231	ARA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409383	25910231	ARA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409383	25910231	ARA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409383	25910231	DMS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409383	25910231	DMS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409383	25910231	DMS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409383	25910231	FRK	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409383	25910231	MAR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409383	25910231	MAR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409383	25910231	MAR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409383	25910231	MAR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409383	25910231	ZGC	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409383	25910231	ZGC	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6117497	30168275	ASK	2	developed the initial framework for the manuscript|prepared the initial outline and draft|incorporated revisions and coordinated the approval from all authors prior to submission|facilitated office clearance	developed the initial framework for the manuscript	Wrote the paper	Writing - Original Draft	YES
6117497	30168275	ASK	2	developed the initial framework for the manuscript|prepared the initial outline and draft|incorporated revisions and coordinated the approval from all authors prior to submission|facilitated office clearance	prepared the initial outline and draft	Wrote the paper	Writing - Original Draft	YES
6117497	30168275	ASK	2	developed the initial framework for the manuscript|prepared the initial outline and draft|incorporated revisions and coordinated the approval from all authors prior to submission|facilitated office clearance	incorporated revisions and coordinated the approval from all authors prior to submission	Wrote the paper	Project administration|Writing - Review & Editing	YES
6117497	30168275	ASK	2	developed the initial framework for the manuscript|prepared the initial outline and draft|incorporated revisions and coordinated the approval from all authors prior to submission|facilitated office clearance	facilitated office clearance	-	-	NO
6117497	30168275	BP	2	developed the initial framework for the manuscript|facilitated office clearance	developed the initial framework for the manuscript	Wrote the paper	Writing - Original Draft	YES
6117497	30168275	BP	2	developed the initial framework for the manuscript|facilitated office clearance	facilitated office clearance	-	-	NO
6117497	30168275	DE	2	developed the initial framework for the manuscript	developed the initial framework for the manuscript	Wrote the paper	Writing - Original Draft	YES
6117497	30168275	JK	2	developed the initial framework for the manuscript	developed the initial framework for the manuscript	Wrote the paper	Writing - Original Draft	YES
6117497	30168275	MOD	2	performed the data analysis and data interpretation	performed the data analysis and data interpretation	Analyzed the data	Formal analysis	YES
6117497	30168275	all authors	2	reviewed and provided revisions to the draft	reviewed and provided revisions to the draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5643487	29075280	CE-M	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5643487	29075280	EB-Q	2	designed, planned, wrote, and checked the manuscript	designed, planned, wrote, and checked the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
5643487	29075280	IE-M	2	checked the manuscript	checked the manuscript	Wrote the paper	Writing - Review & Editing	YES
5643487	29075280	MM-E	2	group leader, wrote and checked the manuscript	group leader, wrote and checked the manuscript	Wrote the paper	Supervision|Writing - Original Draft|Writing - Review & Editing	YES
1791715	17299582	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1791715	17299582	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1791715	17299582	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1791715	17299582	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1791715	17299582	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5461723	28587624	ED	2	conceived of the study and funded the genome sequencing	conceived of the study and funded the genome sequencing	Conceived and designed the experiments|Performed the experiments	Conceptualization|Funding acquisition|Investigation	YES
5461723	28587624	MSU	2	analyzed the genome and wrote the manuscript	analyzed the genome and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5461723	28587624	NR	2	analyzed the genome and wrote the manuscript	analyzed the genome and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4608036	26438278	A.I.	2	coordinated the study and performed the data analysis	coordinated the study and performed the data analysis	Analyzed the data	Formal analysis|Project administration	YES
4608036	26438278	A.P.L.	2	coordinated the study and performed the data analysis|gave final approval for publication	coordinated the study and performed the data analysis	Analyzed the data	Formal analysis|Project administration	YES
4608036	26438278	A.P.L.	2	coordinated the study and performed the data analysis|gave final approval for publication	gave final approval for publication	-	-	NO
4608036	26438278	All authors	2	gave final approval for publication	gave final approval for publication	-	-	NO
4608036	26438278	C.S.B.	2	gave final approval for publication	gave final approval for publication	-	-	NO
4608036	26438278	H.K.	2	gave final approval for publication	gave final approval for publication	-	-	NO
4608036	26438278	J.N.S.C.	2	coordinated the study and performed the data analysis|gave final approval for publication	coordinated the study and performed the data analysis	Analyzed the data	Formal analysis|Project administration	YES
4608036	26438278	J.N.S.C.	2	coordinated the study and performed the data analysis|gave final approval for publication	gave final approval for publication	-	-	NO
4608036	26438278	J.V.	2	coordinated the study and performed the data analysis|gave final approval for publication	coordinated the study and performed the data analysis	Analyzed the data	Formal analysis|Project administration	YES
4608036	26438278	J.V.	2	coordinated the study and performed the data analysis|gave final approval for publication	gave final approval for publication	-	-	NO
4608036	26438278	M.D.W.	2	coordinated the study and performed the data analysis|gave final approval for publication	coordinated the study and performed the data analysis	Analyzed the data	Formal analysis|Project administration	YES
4608036	26438278	M.D.W.	2	coordinated the study and performed the data analysis|gave final approval for publication	gave final approval for publication	-	-	NO
4608036	26438278	M.J.W.	2	coordinated the study and performed the data analysis|coordinated the study and performed the data analysis	coordinated the study and performed the data analysis	Analyzed the data	Formal analysis|Project administration	YES
4608036	26438278	M.J.W.	2	coordinated the study and performed the data analysis|coordinated the study and performed the data analysis	coordinated the study and performed the data analysis	Analyzed the data	Formal analysis|Project administration	YES
4608036	26438278	M.W.	2	coordinated the study and performed the data analysis|gave final approval for publication	coordinated the study and performed the data analysis	Analyzed the data	Formal analysis|Project administration	YES
4608036	26438278	M.W.	2	coordinated the study and performed the data analysis|gave final approval for publication	gave final approval for publication	-	-	NO
4608036	26438278	M.Z.	2	coordinated the study and performed the data analysis|gave final approval for publication	coordinated the study and performed the data analysis	Analyzed the data	Formal analysis|Project administration	YES
4608036	26438278	M.Z.	2	coordinated the study and performed the data analysis|gave final approval for publication	gave final approval for publication	-	-	NO
4608036	26438278	R.R.	2	coordinated the study and performed the data analysis|gave final approval for publication	coordinated the study and performed the data analysis	Analyzed the data	Formal analysis|Project administration	YES
4608036	26438278	R.R.	2	coordinated the study and performed the data analysis|gave final approval for publication	gave final approval for publication	-	-	NO
4608036	26438278	S.B.	2	gave final approval for publication	gave final approval for publication	-	-	NO
4608036	26438278	S.C.S.	2	gave final approval for publication	gave final approval for publication	-	-	NO
4608036	26438278	S.M.K.	2	gave final approval for publication	gave final approval for publication	-	-	NO
4608036	26438278	T.K.	2	coordinated the study and performed the data analysis	coordinated the study and performed the data analysis	Analyzed the data	Formal analysis|Project administration	YES
4608036	26438278	T.M.	2	coordinated the study and performed the data analysis|gave final approval for publication	coordinated the study and performed the data analysis	Analyzed the data	Formal analysis|Project administration	YES
4608036	26438278	T.M.	2	coordinated the study and performed the data analysis|gave final approval for publication	gave final approval for publication	-	-	NO
4608036	26438278	T.O.	2	gave final approval for publication	gave final approval for publication	-	-	NO
4608036	26438278	Y.S.	2	coordinated the study and performed the data analysis	coordinated the study and performed the data analysis	Analyzed the data	Formal analysis|Project administration	YES
4265888	25520903	AJH	2	participated in the design of the microbiological analyses	participated in the design of the microbiological analyses	Conceived and designed the experiments|Analyzed the data	Formal analysis	YES
4265888	25520903	AR	2	participated in the design of the study and drafting the manuscript	participated in the design of the study and drafting the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4265888	25520903	CT	2	imaging and participated in the data analysis and helped to draft the manuscript	imaging and participated in the data analysis and helped to draft the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Visualization|Writing - Original Draft	YES
4265888	25520903	EE	2	participated in the design of the microbiological analyses	participated in the design of the microbiological analyses	Conceived and designed the experiments|Analyzed the data	Formal analysis	YES
4265888	25520903	HTA	2	conceived the study and participated in its design, performed the experimental surgery, and drafted the manuscript	conceived the study and participated in its design, performed the experimental surgery, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Writing - Original Draft	YES
4265888	25520903	JK	2	contributed in the design of the microbiological analyses and carried out imaging with a fluorescence microscope and participated in the data analysis and helped to draft the manuscript	contributed in the design of the microbiological analyses and carried out imaging with a fluorescence microscope and participated in the data analysis and helped to draft the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Visualization|Writing - Original Draft	YES
4265888	25520903	MS	2	performed the histopathological analysis	performed the histopathological analysis	Performed the experiments	Investigation	YES
4265888	25520903	NM	2	participated in the experimental surgery and performed the statistical analysis	participated in the experimental surgery and performed the statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4265888	25520903	SJ	2	participated in the design of the study and drafting the manuscript	participated in the design of the study and drafting the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4265888	25520903	TS	2	participated in the pet imaging	participated in the pet imaging	Analyzed the data	Visualization	YES
1794132	17311091	EB	PLoS5	Conceived and designed the experiments|Manuscript revision	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1794132	17311091	EB	PLoS5	Conceived and designed the experiments|Manuscript revision	Manuscript revision	Wrote the paper	Writing - Review & Editing	YES
1794132	17311091	EM	PLoS5	Conceived and designed the experiments|Manuscript revision	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1794132	17311091	EM	PLoS5	Conceived and designed the experiments|Manuscript revision	Manuscript revision	Wrote the paper	Writing - Review & Editing	YES
1794132	17311091	HH	PLoS5	Participated in data compilation	Participated in data compilation	-	-	NO
1794132	17311091	MC	PLoS5	Participated in data compilation	Participated in data compilation	-	-	NO
1794132	17311091	XX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Obtained funding	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1794132	17311091	XX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Obtained funding	Performed the experiments	Performed the experiments	Investigation	YES
1794132	17311091	XX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Obtained funding	Analyzed the data	Analyzed the data	Formal analysis	YES
1794132	17311091	XX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Obtained funding	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1794132	17311091	XX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Obtained funding	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1794132	17311091	XX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Obtained funding	Obtained funding	-	Funding acquisition	YES
4480253	26130914	Ajeet Kumar	7	Himanshu	Himanshu	-	-	NO
4480253	26130914	K Mishra	7	Carried out the experiments. Jamuna	Carried out the experiments. Jamuna	Performed the experiments	Investigation	YES
4480253	26130914	Priyanka Dwivedi	7	Carried out the experiments. Jamuna	Carried out the experiments. Jamuna	Performed the experiments	Investigation	YES
4480253	26130914	R Subramaniam	7	Designed, carried out, supervised, and wrote the manuscript	Designed, carried out, supervised, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Original Draft	YES
5643848	29075271	All authors	2	have read and approved the final manuscript	have read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5643848	29075271	FL	2	carried out experiments	carried out experiments	Performed the experiments	Investigation	YES
5643848	29075271	HX	2	carried out experiments	carried out experiments	Performed the experiments	Investigation	YES
5643848	29075271	HZ	2	helped to revise the manuscript	helped to revise the manuscript	Wrote the paper	Writing - Review & Editing	YES
5643848	29075271	LY	2	carried out experiments|analyzed experimental results|wrote the manuscript	carried out experiments	Performed the experiments	Investigation	YES
5643848	29075271	LY	2	carried out experiments|analyzed experimental results|wrote the manuscript	analyzed experimental results	Analyzed the data	Formal analysis	YES
5643848	29075271	LY	2	carried out experiments|analyzed experimental results|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5643848	29075271	QS	2	conceived the project|wrote the manuscript	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5643848	29075271	QS	2	conceived the project|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5643848	29075271	XZ	2	carried out experiments	carried out experiments	Performed the experiments	Investigation	YES
5643848	29075271	ZN	2	conceived the project|wrote the manuscript	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5643848	29075271	ZN	2	conceived the project|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6138437	30375818	AEP	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
6138437	30375818	AIMH	PLoS52	enabled access to patient samples	enabled access to patient samples	-	-	NO
6138437	30375818	AMJW	PLoS52	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6138437	30375818	All authors	PLoS52	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
6138437	30375818	DMCdJ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
6138437	30375818	KJB	PLoS52	designed the study|performed the experiments|analysed the data|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
6138437	30375818	KJB	PLoS52	designed the study|performed the experiments|analysed the data|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
6138437	30375818	KJB	PLoS52	designed the study|performed the experiments|analysed the data|wrote the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
6138437	30375818	KJB	PLoS52	designed the study|performed the experiments|analysed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6138437	30375818	MN	PLoS52	designed the study|analysed the data|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
6138437	30375818	MN	PLoS52	designed the study|analysed the data|wrote the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
6138437	30375818	MN	PLoS52	designed the study|analysed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6138437	30375818	PMvH	PLoS52	designed the study|performed the experiments	designed the study	Conceived and designed the experiments	Methodology	YES
6138437	30375818	PMvH	PLoS52	designed the study|performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
6138437	30375818	WJvS	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
4409384	25909514	AN	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409384	25909514	BHA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409384	25909514	BHA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409384	25909514	BHA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409384	25909514	BHA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409384	25909514	BHA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409384	25909514	JY	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409384	25909514	MAZ	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409384	25909514	MAZ	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409384	25909514	MAZ	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409384	25909514	MIW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409384	25909514	NS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409384	25909514	SA	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4273686	25593791	AF	2	was responsible for implementation of the study, data acquisition, performing the experiments, analysing the results and preparing the manuscript	was responsible for implementation of the study, data acquisition, performing the experiments, analysing the results and preparing the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4273686	25593791	JD	2	contributed to the study design as well as analysis of the results and reviewing the manuscript	contributed to the study design as well as analysis of the results and reviewing the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
4273686	25593791	MK	2	contributed to the study design as well as analysis of the results and reviewing the manuscript	contributed to the study design as well as analysis of the results and reviewing the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
5461734	28587594	All the authors	PLoS52	discussed the results of the manuscript and reviewed the manuscript	discussed the results of the manuscript and reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5461734	28587594	CZH	PLoS52	helped in the execution of some experiments	helped in the execution of some experiments	Performed the experiments	Investigation	YES
5461734	28587594	DJJ	PLoS52	helped in the execution of some experiments	helped in the execution of some experiments	Performed the experiments	Investigation	YES
5461734	28587594	HWS	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5461734	28587594	LMX	PLoS52	helped in the execution of some experiments	helped in the execution of some experiments	Performed the experiments	Investigation	YES
5461734	28587594	NYC	PLoS52	analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5461734	28587594	NYC	PLoS52	analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5461734	28587594	SCF	PLoS52	executed the experiments|wrote the manuscript	executed the experiments	Performed the experiments	Investigation	YES
5461734	28587594	SCF	PLoS52	executed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5461734	28587594	TYY	PLoS52	helped in the execution of some experiments	helped in the execution of some experiments	Performed the experiments	Investigation	YES
5461734	28587594	YX	PLoS52	conceived and designed this work|wrote the manuscript	conceived and designed this work	Conceived and designed the experiments	Conceptualization	YES
5461734	28587594	YX	PLoS52	conceived and designed this work|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5461734	28587594	ZJ	PLoS52	helped in the execution of some experiments	helped in the execution of some experiments	Performed the experiments	Investigation	YES
5461734	28587594	ZQK	PLoS52	helped in the execution of some experiments	helped in the execution of some experiments	Performed the experiments	Investigation	YES
4608037	26438279	J.M.G.	2	designed the study, carried out the data analysis and drafted the manuscript	designed the study, carried out the data analysis and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4608037	26438279	P.G.	2	made substantial intellectual contributions to the concepts described in the manuscript and reviewed it critically	made substantial intellectual contributions to the concepts described in the manuscript and reviewed it critically	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
4608037	26438279	T.A.	2	made substantial intellectual contributions to the concepts described in the manuscript and reviewed it critically	made substantial intellectual contributions to the concepts described in the manuscript and reviewed it critically	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
1794133	17311092	AS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1794133	17311092	BP	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1794133	17311092	CL	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1794133	17311092	CL	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1794133	17311092	EV	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1794133	17311092	EV	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1794133	17311092	EV	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1794133	17311092	JG	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1794133	17311092	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1794133	17311092	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1794133	17311092	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1794133	17311092	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1794133	17311092	NV	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1794133	17311092	PB	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1794133	17311092	SJ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1794133	17311092	SR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1794133	17311092	SR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1794133	17311092	SR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1794133	17311092	SU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1794133	17311092	SU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1794133	17311092	SU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1794133	17311092	SU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409386	25909322	DY	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409386	25909322	HD	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409386	25909322	JH	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4409386	25909322	JH	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409386	25909322	JL	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409386	25909322	JX	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409386	25909322	JX	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409386	25909322	NY	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409386	25909322	SL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409386	25909322	SL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409386	25909322	SL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409386	25909322	SW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409386	25909322	SW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409386	25909322	SW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409386	25909322	SW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409386	25909322	XP	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409386	25909322	ZL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4409386	25909322	ZL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4480254	26130909	Amit Kumar	7	Analysis	Analysis	-	-	NO
4480254	26130909	K Pandit	7	Manuscript writing	Manuscript writing	Wrote the paper	Writing - Original Draft	YES
4480254	26130909	K Yadav	7	Data search and extraction	Data search and extraction	-	Data curation	YES
4480254	26130909	Kameshwar Prasad	7	Concept and designing of manuscript	Concept and designing of manuscript	Conceived and designed the experiments	Conceptualization	YES
4480254	26130909	Pradeep Kumar	7	Concept, data search, extraction and writing of manuscript, Arun	Concept, data search, extraction and writing of manuscript, Arun	Conceived and designed the experiments|Wrote the paper	Conceptualization|Data curation|Writing - Original Draft	YES
4480254	26130909	Ram Sagar	7	Data entry, Awadh	Data entry, Awadh	Analyzed the data	Data curation	YES
6141897	30225946	All authors	PLoS52	contributed to the writing and approved the final manuscript	contributed to the writing and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6141897	30225946	BK	PLoS52	designed and planned the research|performed and/or supervised the implementation|wrote the first draft of the manuscript	designed and planned the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
6141897	30225946	BK	PLoS52	designed and planned the research|performed and/or supervised the implementation|wrote the first draft of the manuscript	performed and/or supervised the implementation	Performed the experiments	Investigation|Supervision	YES
6141897	30225946	BK	PLoS52	designed and planned the research|performed and/or supervised the implementation|wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
6141897	30225946	BR	PLoS52	designed and planned the research|performed and/or supervised the implementation	designed and planned the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
6141897	30225946	BR	PLoS52	designed and planned the research|performed and/or supervised the implementation	performed and/or supervised the implementation	Performed the experiments	Investigation|Supervision	YES
6141897	30225946	GS	PLoS52	designed and planned the research|performed and/or supervised the implementation	designed and planned the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
6141897	30225946	GS	PLoS52	designed and planned the research|performed and/or supervised the implementation	performed and/or supervised the implementation	Performed the experiments	Investigation|Supervision	YES
6141897	30225946	IC	PLoS52	designed and planned the research|performed and/or supervised the implementation	designed and planned the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
6141897	30225946	IC	PLoS52	designed and planned the research|performed and/or supervised the implementation	performed and/or supervised the implementation	Performed the experiments	Investigation|Supervision	YES
6141897	30225946	LP	PLoS52	designed and planned the research|performed and/or supervised the implementation|analysed the data|wrote the first draft of the manuscript	designed and planned the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
6141897	30225946	LP	PLoS52	designed and planned the research|performed and/or supervised the implementation|analysed the data|wrote the first draft of the manuscript	performed and/or supervised the implementation	Performed the experiments	Investigation|Supervision	YES
6141897	30225946	LP	PLoS52	designed and planned the research|performed and/or supervised the implementation|analysed the data|wrote the first draft of the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
6141897	30225946	LP	PLoS52	designed and planned the research|performed and/or supervised the implementation|analysed the data|wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
6141897	30225946	MP	PLoS52	performed and/or supervised the implementation	performed and/or supervised the implementation	Performed the experiments	Investigation|Supervision	YES
6141897	30225946	NL	PLoS52	performed and/or supervised the implementation	performed and/or supervised the implementation	Performed the experiments	Investigation|Supervision	YES
6141897	30225946	RN	PLoS52	analysed the data|wrote the first draft of the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
6141897	30225946	RN	PLoS52	analysed the data|wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
6141897	30225946	SM	PLoS52	designed and planned the research|performed and/or supervised the implementation	designed and planned the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
6141897	30225946	SM	PLoS52	designed and planned the research|performed and/or supervised the implementation	performed and/or supervised the implementation	Performed the experiments	Investigation|Supervision	YES
6141897	30225946	SMK	PLoS52	designed and planned the research|performed and/or supervised the implementation	designed and planned the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
6141897	30225946	SMK	PLoS52	designed and planned the research|performed and/or supervised the implementation	performed and/or supervised the implementation	Performed the experiments	Investigation|Supervision	YES
6141897	30225946	SN	PLoS52	designed and planned the research|performed and/or supervised the implementation	designed and planned the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
6141897	30225946	SN	PLoS52	designed and planned the research|performed and/or supervised the implementation	performed and/or supervised the implementation	Performed the experiments	Investigation|Supervision	YES
5644052	29075270	DC	2	critically evaluated the manuscript	critically evaluated the manuscript	-	-	NO
5644052	29075270	DT	2	critically evaluated the manuscript	critically evaluated the manuscript	-	-	NO
5644052	29075270	JS	2	performed the experiment and wrote the manuscript	performed the experiment and wrote the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5644052	29075270	NU	2	designed the manuscript|performed the experiment and wrote the manuscript	designed the manuscript	Conceived and designed the experiments	-	YES
5644052	29075270	NU	2	designed the manuscript|performed the experiment and wrote the manuscript	performed the experiment and wrote the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5644052	29075270	SL	2	critically evaluated the manuscript	critically evaluated the manuscript	-	-	NO
5644052	29075270	SP	2	designed the manuscript	designed the manuscript	Conceived and designed the experiments	-	YES
5644052	29075270	SS	2	critically evaluated the manuscript	critically evaluated the manuscript	-	-	NO
5644052	29075270	VS	2	designed the manuscript	designed the manuscript	Conceived and designed the experiments	-	YES
1794134	17311093	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1794134	17311093	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1794134	17311093	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1794134	17311093	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1794134	17311093	EC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1794134	17311093	EC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1794134	17311093	EC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1794134	17311093	EC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1794134	17311093	HA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1794134	17311093	HA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1794134	17311093	HA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1794134	17311093	HA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1794134	17311093	LM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5461738	28587595	HZC	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5461738	28587595	SZY	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5461738	28587595	WYZ	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|contributed reagents/materials/analysis tools|conceived the experiments and wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5461738	28587595	WYZ	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|contributed reagents/materials/analysis tools|conceived the experiments and wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5461738	28587595	WYZ	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|contributed reagents/materials/analysis tools|conceived the experiments and wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5461738	28587595	WYZ	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|contributed reagents/materials/analysis tools|conceived the experiments and wrote the manuscript	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5461738	28587595	WYZ	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|contributed reagents/materials/analysis tools|conceived the experiments and wrote the manuscript	conceived the experiments and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5461738	28587595	XMT	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5461738	28587595	ZDS	PLoS52	conceived and designed the experiments|contributed reagents/materials/analysis tools|conceived the experiments and wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5461738	28587595	ZDS	PLoS52	conceived and designed the experiments|contributed reagents/materials/analysis tools|conceived the experiments and wrote the manuscript	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5461738	28587595	ZDS	PLoS52	conceived and designed the experiments|contributed reagents/materials/analysis tools|conceived the experiments and wrote the manuscript	conceived the experiments and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5461738	28587595	ZGL	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5461738	28587595	ZYC	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
4409387	25909991	GG	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4409387	25909991	GG	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409387	25909991	HF	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409387	25909991	SL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4409387	25909991	SL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409387	25909991	WL	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409387	25909991	XL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409387	25909991	XL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409387	25909991	XL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409387	25909991	XL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409387	25909991	YD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409387	25909991	YD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409387	25909991	YD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409387	25909991	YD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4480258	26130916	Akshay Anand	7	Substantial contributions to conception, design, revising it critically for important intellectual content,. Final approval of the version to be published	Substantial contributions to conception, design, revising it critically for important intellectual content,. Final approval of the version to be published	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
4480258	26130916	D De	7	Substantial contributions to editing the article	Substantial contributions to editing the article	Wrote the paper	Writing - Review & Editing	YES
4480258	26130916	K. Ranil	7	Substantial contributions to editing the article	Substantial contributions to editing the article	Wrote the paper	Writing - Review & Editing	YES
4480258	26130916	Manju Mohanty	7	Substantial contributions to editing the article	Substantial contributions to editing the article	Wrote the paper	Writing - Review & Editing	YES
4480258	26130916	Manoj Goyal	7	Substantial contributions to editing the article	Substantial contributions to editing the article	Wrote the paper	Writing - Review & Editing	YES
4480258	26130916	Rahul Tyagi	7	Substantial contributions to drafting the article	Substantial contributions to drafting the article	Wrote the paper	Writing - Original Draft	YES
4480258	26130916	Silva Nalaka Wijekoon	7	Substantial contributions to editing the article	Substantial contributions to editing the article	Wrote the paper	Writing - Review & Editing	YES
1794142	17311094	BL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1794142	17311094	BL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1794142	17311094	BL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1794142	17311094	BL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1794142	17311094	CW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1794142	17311094	SG	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1794142	17311094	SG	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6141900	30225908	ANK	PLoS52	contributed to the conception of the analysis idea|contributed to data collection and cleaning|analysed the data|wrote the manuscript|reviewed and contributed to the manuscript	contributed to the conception of the analysis idea	Conceived and designed the experiments	Conceptualization	YES
6141900	30225908	ANK	PLoS52	contributed to the conception of the analysis idea|contributed to data collection and cleaning|analysed the data|wrote the manuscript|reviewed and contributed to the manuscript	contributed to data collection and cleaning	Performed the experiments	Data curation|Investigation	YES
6141900	30225908	ANK	PLoS52	contributed to the conception of the analysis idea|contributed to data collection and cleaning|analysed the data|wrote the manuscript|reviewed and contributed to the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
6141900	30225908	ANK	PLoS52	contributed to the conception of the analysis idea|contributed to data collection and cleaning|analysed the data|wrote the manuscript|reviewed and contributed to the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6141900	30225908	ANK	PLoS52	contributed to the conception of the analysis idea|contributed to data collection and cleaning|analysed the data|wrote the manuscript|reviewed and contributed to the manuscript	reviewed and contributed to the manuscript	Wrote the paper	Writing - Review & Editing	YES
6141900	30225908	BE	PLoS52	contributed to the conception of the analysis idea|wrote the manuscript|reviewed and contributed to the manuscript|gave overall technical oversight for the analytic process and manuscript writing	contributed to the conception of the analysis idea	Conceived and designed the experiments	Conceptualization	YES
6141900	30225908	BE	PLoS52	contributed to the conception of the analysis idea|wrote the manuscript|reviewed and contributed to the manuscript|gave overall technical oversight for the analytic process and manuscript writing	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6141900	30225908	BE	PLoS52	contributed to the conception of the analysis idea|wrote the manuscript|reviewed and contributed to the manuscript|gave overall technical oversight for the analytic process and manuscript writing	reviewed and contributed to the manuscript	Wrote the paper	Writing - Review & Editing	YES
6141900	30225908	BE	PLoS52	contributed to the conception of the analysis idea|wrote the manuscript|reviewed and contributed to the manuscript|gave overall technical oversight for the analytic process and manuscript writing	gave overall technical oversight for the analytic process and manuscript writing	Wrote the paper	Supervision|Writing - Original Draft	YES
6141900	30225908	BSM	PLoS52	contributed to data collection and cleaning|analysed the data|reviewed and contributed to the manuscript	contributed to data collection and cleaning	Performed the experiments	Data curation|Investigation	YES
6141900	30225908	BSM	PLoS52	contributed to data collection and cleaning|analysed the data|reviewed and contributed to the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
6141900	30225908	BSM	PLoS52	contributed to data collection and cleaning|analysed the data|reviewed and contributed to the manuscript	reviewed and contributed to the manuscript	Wrote the paper	Writing - Review & Editing	YES
6141900	30225908	CTY	PLoS52	contributed to the conception of the analysis idea|contributed to data collection and cleaning|analysed the data|wrote the manuscript|reviewed and contributed to the manuscript	contributed to the conception of the analysis idea	Conceived and designed the experiments	Conceptualization	YES
6141900	30225908	CTY	PLoS52	contributed to the conception of the analysis idea|contributed to data collection and cleaning|analysed the data|wrote the manuscript|reviewed and contributed to the manuscript	contributed to data collection and cleaning	Performed the experiments	Data curation|Investigation	YES
6141900	30225908	CTY	PLoS52	contributed to the conception of the analysis idea|contributed to data collection and cleaning|analysed the data|wrote the manuscript|reviewed and contributed to the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
6141900	30225908	CTY	PLoS52	contributed to the conception of the analysis idea|contributed to data collection and cleaning|analysed the data|wrote the manuscript|reviewed and contributed to the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6141900	30225908	CTY	PLoS52	contributed to the conception of the analysis idea|contributed to data collection and cleaning|analysed the data|wrote the manuscript|reviewed and contributed to the manuscript	reviewed and contributed to the manuscript	Wrote the paper	Writing - Review & Editing	YES
6141900	30225908	EJA	PLoS52	contributed to the conception of the analysis idea|reviewed and contributed to the manuscript	contributed to the conception of the analysis idea	Conceived and designed the experiments	Conceptualization	YES
6141900	30225908	EJA	PLoS52	contributed to the conception of the analysis idea|reviewed and contributed to the manuscript	reviewed and contributed to the manuscript	Wrote the paper	Writing - Review & Editing	YES
6141900	30225908	EL	PLoS52	contributed to data collection and cleaning|reviewed and contributed to the manuscript	contributed to data collection and cleaning	Performed the experiments	Data curation|Investigation	YES
6141900	30225908	EL	PLoS52	contributed to data collection and cleaning|reviewed and contributed to the manuscript	reviewed and contributed to the manuscript	Wrote the paper	Writing - Review & Editing	YES
6141900	30225908	HF	PLoS52	contributed to data collection and cleaning	contributed to data collection and cleaning	Performed the experiments	Data curation|Investigation	YES
6141900	30225908	HNB	PLoS52	contributed to the conception of the analysis idea|contributed to data collection and cleaning|wrote the manuscript|reviewed and contributed to the manuscript	contributed to the conception of the analysis idea	Conceived and designed the experiments	Conceptualization	YES
6141900	30225908	HNB	PLoS52	contributed to the conception of the analysis idea|contributed to data collection and cleaning|wrote the manuscript|reviewed and contributed to the manuscript	contributed to data collection and cleaning	Performed the experiments	Data curation|Investigation	YES
6141900	30225908	HNB	PLoS52	contributed to the conception of the analysis idea|contributed to data collection and cleaning|wrote the manuscript|reviewed and contributed to the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6141900	30225908	HNB	PLoS52	contributed to the conception of the analysis idea|contributed to data collection and cleaning|wrote the manuscript|reviewed and contributed to the manuscript	reviewed and contributed to the manuscript	Wrote the paper	Writing - Review & Editing	YES
6141900	30225908	HW	PLoS52	reviewed and contributed to the manuscript	reviewed and contributed to the manuscript	Wrote the paper	Writing - Review & Editing	YES
6141900	30225908	JS	PLoS52	contributed to data collection and cleaning|reviewed and contributed to the manuscript	contributed to data collection and cleaning	Performed the experiments	Data curation|Investigation	YES
6141900	30225908	JS	PLoS52	contributed to data collection and cleaning|reviewed and contributed to the manuscript	reviewed and contributed to the manuscript	Wrote the paper	Writing - Review & Editing	YES
6141900	30225908	KWK	PLoS52	contributed to the conception of the analysis idea|reviewed and contributed to the manuscript	contributed to the conception of the analysis idea	Conceived and designed the experiments	Conceptualization	YES
6141900	30225908	KWK	PLoS52	contributed to the conception of the analysis idea|reviewed and contributed to the manuscript	reviewed and contributed to the manuscript	Wrote the paper	Writing - Review & Editing	YES
6141900	30225908	SA	PLoS52	contributed to data collection and cleaning|reviewed and contributed to the manuscript	contributed to data collection and cleaning	Performed the experiments	Data curation|Investigation	YES
6141900	30225908	SA	PLoS52	contributed to data collection and cleaning|reviewed and contributed to the manuscript	reviewed and contributed to the manuscript	Wrote the paper	Writing - Review & Editing	YES
5644155	29075277	EA	PLoS52	helped to draft the manuscript and revised manuscript	helped to draft the manuscript and revised manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5644155	29075277	GW	PLoS52	assisted with doing the experiments	assisted with doing the experiments	Performed the experiments	Investigation	YES
5644155	29075277	JF	PLoS52	designed the experiments|helped to draft the manuscript and revised manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5644155	29075277	JF	PLoS52	designed the experiments|helped to draft the manuscript and revised manuscript	helped to draft the manuscript and revised manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5644155	29075277	LZ	PLoS52	performed the experiments, and wrote the manuscript	performed the experiments, and wrote the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5644155	29075277	TH	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5644155	29075277	YX	PLoS52	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
4409389	25909998	FFM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409389	25909998	KZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409389	25909998	KZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409389	25909998	KZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409389	25909998	KZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409389	25909998	SNY	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4409389	25909998	SNY	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409389	25909998	XFG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409389	25909998	XFG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409389	25909998	XFG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409389	25909998	YCZ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409389	25909998	YZZ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409389	25909998	YZZ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4480259	26130910	Anuja Chandak Shweta	7	Statistical analysis, Dhananjay V	Statistical analysis, Dhananjay V	Analyzed the data	Formal analysis	YES
4480259	26130910	Daginawala Rajpal	7	Conception & design, critical revision of the article and overall responsibility	Conception & design, critical revision of the article and overall responsibility	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
4480259	26130910	H Lande	7	Data collection, Dinesh	Data collection, Dinesh	Performed the experiments	Investigation	YES
4480259	26130910	M Taori	7	Final approval of the article, Hatim F	Final approval of the article, Hatim F	-	-	NO
4480259	26130910	P Kabra	7	Analysis & interpretation of data, Nitin H	Analysis & interpretation of data, Nitin H	Analyzed the data	Formal analysis	YES
4480259	26130910	P Kawle	7	Article drafting and data collection, Amit	Article drafting and data collection, Amit	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4480259	26130910	R Badar	7	Statistical analysis, Dhananjay V	Statistical analysis, Dhananjay V	Analyzed the data	Formal analysis	YES
4480259	26130910	R Nayak	7	Conception & design and analysis and interpretation of data, Neha	Conception & design and analysis and interpretation of data, Neha	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
4480259	26130910	Raje Girdhar	7	Final approval of the article, Hatim F	Final approval of the article, Hatim F	-	-	NO
4480259	26130910	S Kashyap	7	Conception & design, critical revision of the article and overall responsibility	Conception & design, critical revision of the article and overall responsibility	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
546212	15647114	BF	2	characterized psg genomic clones and performed psg expression studies	characterized psg genomic clones and performed psg expression studies	Performed the experiments	Investigation	YES
546212	15647114	GD	2	isolated the psg bac clones and analysed psg32 exon 1 sequences in mouse strains	isolated the psg bac clones and analysed psg32 exon 1 sequences in mouse strains	Performed the experiments	Investigation	YES
546212	15647114	YAC	2	fragment assembly	fragment assembly	-	-	NO
1794152	17311095	AX	PLoS5	Revised the paper and provided the source of funding for the students	Revised the paper and provided the source of funding for the students	Wrote the paper	Funding acquisition|Writing - Review & Editing	YES
1794152	17311095	JZ	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1794152	17311095	JZ	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1794152	17311095	TZ	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1794152	17311095	TZ	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1794152	17311095	ZY	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1794152	17311095	ZY	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
3776380	24082855	Dong-Li Fu	2	contributed equally to this work and should be considered as cofirst authors	contributed equally to this work and should be considered as cofirst authors	-	-	NO
3776380	24082855	Guang-Li Yang	2	contributed equally to this work and should be considered as cofirst authors	contributed equally to this work and should be considered as cofirst authors	-	-	NO
5644244	29075275	AL	PLoS52	contributed reagents/materials/analysis tools	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5644244	29075275	CL	PLoS52	conceived and designed the experiments|performed disease resistance testing	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5644244	29075275	CL	PLoS52	conceived and designed the experiments|performed disease resistance testing	performed disease resistance testing	Performed the experiments	Investigation	YES
5644244	29075275	DC	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5644244	29075275	GL	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5644244	29075275	HL	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5644244	29075275	HY	PLoS52	performed disease resistance testing	performed disease resistance testing	Performed the experiments	Investigation	YES
5644244	29075275	JG	PLoS52	performed disease resistance testing	performed disease resistance testing	Performed the experiments	Investigation	YES
5644244	29075275	JL	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5644244	29075275	JS	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5644244	29075275	RH	PLoS52	performed the experiments|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5644244	29075275	RH	PLoS52	performed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5644244	29075275	SZ	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5644244	29075275	WG	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5644244	29075275	XC	PLoS52	contributed reagents/materials/analysis tools	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5644244	29075275	ZZ	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
6141901	30225927	All authors	PLoS52	critically reviewed and approved the manuscript	critically reviewed and approved the manuscript	Wrote the paper	Writing - Review & Editing	YES
6141901	30225927	CL	PLoS52	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
6141901	30225927	DT	PLoS52	designed the analysis|analysed the data	designed the analysis	Conceived and designed the experiments	-	YES
6141901	30225927	DT	PLoS52	designed the analysis|analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
6141901	30225927	JJ	PLoS52	coordinated the study and oversaw data management	coordinated the study and oversaw data management	Analyzed the data	Data curation|Project administration|Supervision	YES
6141901	30225927	KPa	PLoS52	implemented the study at their sites	implemented the study at their sites	Performed the experiments	Investigation	YES
6141901	30225927	KPu	PLoS52	conducted study monitoring	conducted study monitoring	Performed the experiments	Investigation|Supervision	YES
6141901	30225927	KT	PLoS52	implemented the study at their sites	implemented the study at their sites	Performed the experiments	Investigation	YES
6141901	30225927	NP	PLoS52	designed the study|led the study and wrote the first draft of the report|designed the analysis	designed the study	Conceived and designed the experiments	Methodology	YES
6141901	30225927	NP	PLoS52	designed the study|led the study and wrote the first draft of the report|designed the analysis	led the study and wrote the first draft of the report	Wrote the paper	Writing - Original Draft	YES
6141901	30225927	NP	PLoS52	designed the study|led the study and wrote the first draft of the report|designed the analysis	designed the analysis	Conceived and designed the experiments	-	YES
6141901	30225927	NT	PLoS52	implemented the study at their sites	implemented the study at their sites	Performed the experiments	Investigation	YES
6141901	30225927	PC	PLoS52	implemented the study at their sites	implemented the study at their sites	Performed the experiments	Investigation	YES
6141901	30225927	PPa	PLoS52	implemented the study at their sites	implemented the study at their sites	Performed the experiments	Investigation	YES
6141901	30225927	PPh	PLoS52	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
6141901	30225927	SN	PLoS52	coordinated the study and oversaw data management	coordinated the study and oversaw data management	Analyzed the data	Data curation|Project administration|Supervision	YES
6141901	30225927	SPa	PLoS52	performed laboratory testing	performed laboratory testing	Performed the experiments	Investigation	YES
6141901	30225927	SPe	PLoS52	coordinated the study and oversaw data management	coordinated the study and oversaw data management	Analyzed the data	Data curation|Project administration|Supervision	YES
6141901	30225927	SS	PLoS52	implemented the study at their sites	implemented the study at their sites	Performed the experiments	Investigation	YES
6141901	30225927	ST	PLoS52	implemented the study at their sites	implemented the study at their sites	Performed the experiments	Investigation	YES
6141901	30225927	TP	PLoS52	performed laboratory testing	performed laboratory testing	Performed the experiments	Investigation	YES
6141901	30225927	TS	PLoS52	coordinated the study and oversaw data management	coordinated the study and oversaw data management	Analyzed the data	Data curation|Project administration|Supervision	YES
4409390	25910221	BJ	PLoS5	Conceived and designed the experiments|Revised the article critically for important intellectual content	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409390	25910221	BJ	PLoS5	Conceived and designed the experiments|Revised the article critically for important intellectual content	Revised the article critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4409390	25910221	HCS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Revised the article critically for important intellectual content	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409390	25910221	HCS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Revised the article critically for important intellectual content	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409390	25910221	HCS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Revised the article critically for important intellectual content	Revised the article critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4409390	25910221	LJO	PLoS5	Conceived and designed the experiments|Revised the article critically for important intellectual content	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409390	25910221	LJO	PLoS5	Conceived and designed the experiments|Revised the article critically for important intellectual content	Revised the article critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4409390	25910221	LSD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409390	25910221	LSD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409390	25910221	LSD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409390	25910221	MN	PLoS5	Conceived and designed the experiments|Analyzed the data|Revised the article critically for important intellectual content	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409390	25910221	MN	PLoS5	Conceived and designed the experiments|Analyzed the data|Revised the article critically for important intellectual content	Analyzed the data	Analyzed the data	Formal analysis	YES
4409390	25910221	MN	PLoS5	Conceived and designed the experiments|Analyzed the data|Revised the article critically for important intellectual content	Revised the article critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4409390	25910221	OSS	PLoS5	Conceived and designed the experiments|Analyzed the data|Revised the article critically for important intellectual content	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409390	25910221	OSS	PLoS5	Conceived and designed the experiments|Analyzed the data|Revised the article critically for important intellectual content	Analyzed the data	Analyzed the data	Formal analysis	YES
4409390	25910221	OSS	PLoS5	Conceived and designed the experiments|Analyzed the data|Revised the article critically for important intellectual content	Revised the article critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4409390	25910221	SJF	PLoS5	Conceived and designed the experiments|Revised the article critically for important intellectual content	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409390	25910221	SJF	PLoS5	Conceived and designed the experiments|Revised the article critically for important intellectual content	Revised the article critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4608040	26438282	E.H.	4	The data analysis was carried out by	The data analysis was carried out by	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4608040	26438282	E.S.	4	The data analysis was carried out by	The data analysis was carried out by	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4480260	26130912	C Pereira	7	The analysis of the data, design of the project and project write up for subsequent approval	The analysis of the data, design of the project and project write up for subsequent approval	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology	YES
4480260	26130912	Ghaleb Elyamany	7	Initiating the project, design of the project, project write up and final approval	Initiating the project, design of the project, project write up and final approval	Conceived and designed the experiments|Wrote the paper	Methodology	YES
4480260	26130912	Mohammed Tareeqanwar	7	Contributed in conceptualizing the project, data analysis, project write up and subsequent constructive suggestions	Contributed in conceptualizing the project, data analysis, project write up and subsequent constructive suggestions	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Resources	YES
4480260	26130912	Nora El Khizzi	7	Contributed in giving the inputs from Microbiological results in infectious disease testing	Contributed in giving the inputs from Microbiological results in infectious disease testing	Performed the experiments	Investigation	YES
4480260	26130912	Omar Alsuhaibani	7	Verification of Data and part of the group to conceptualize the project, Winston	Verification of Data and part of the group to conceptualize the project, Winston	Conceived and designed the experiments|Performed the experiments	Conceptualization|Validation	YES
4480260	26130912	Saadia Bakheswain	7	Analyzing and verifying data of Microbiological results in infectious disease testing	Analyzing and verifying data of Microbiological results in infectious disease testing	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Validation	YES
1794153	17311096	AV	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1794153	17311096	AV	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1794153	17311096	CA	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1794153	17311096	CA	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1794153	17311096	DB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1794153	17311096	DW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1794153	17311096	DW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1794153	17311096	DW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1794153	17311096	DY	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1794153	17311096	EC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1794153	17311096	JG	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1794153	17311096	JH	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1794153	17311096	JH	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1794153	17311096	JT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1794153	17311096	JT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1794153	17311096	JT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1794153	17311096	MS	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1794153	17311096	PK	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1794153	17311096	PK	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1794153	17311096	RA	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1794153	17311096	SB	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1794153	17311096	SB	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1794153	17311096	SM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4556818	26356073	Catherine Zhang	2	contributed equally	contributed equally	-	-	NO
4556818	26356073	Loredana Campo	2	contributed equally	contributed equally	-	-	NO
5463331	28595597	AM	2	contributed substantially to data interpretation and revisions	contributed substantially to data interpretation and revisions	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
5463331	28595597	AS	2	participated in all steps of the project as coordinators, and critically reviewed the manuscript	participated in all steps of the project as coordinators, and critically reviewed the manuscript	Wrote the paper	Project administration|Writing - Review & Editing	YES
5463331	28595597	AVS	2	contributed substantially to data interpretation and revisions	contributed substantially to data interpretation and revisions	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
5463331	28595597	CSS	2	contributed substantially to data interpretation and revisions	contributed substantially to data interpretation and revisions	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
5463331	28595597	ELF	2	performed bioinformatics analysis of the data	performed bioinformatics analysis of the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5463331	28595597	GHMFS	2	conducted the proteomic analysis	conducted the proteomic analysis	Performed the experiments	Investigation	YES
5463331	28595597	HF	2	contributed substantially to data interpretation and revisions	contributed substantially to data interpretation and revisions	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
5463331	28595597	SCS	2	performed bioinformatics analysis of the data	performed bioinformatics analysis of the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5463331	28595597	VA	2	participated in all steps of the project as coordinators, and critically reviewed the manuscript	participated in all steps of the project as coordinators, and critically reviewed the manuscript	Wrote the paper	Project administration|Writing - Review & Editing	YES
5463331	28595597	WMS	2	performed microbiological analyses and sample preparation for proteomic analysis|conducted the proteomic analysis	performed microbiological analyses and sample preparation for proteomic analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5463331	28595597	WMS	2	performed microbiological analyses and sample preparation for proteomic analysis|conducted the proteomic analysis	conducted the proteomic analysis	Performed the experiments	Investigation	YES
5463331	28595597	YLL	2	participated in all steps of the project as coordinators, and critically reviewed the manuscript	participated in all steps of the project as coordinators, and critically reviewed the manuscript	Wrote the paper	Project administration|Writing - Review & Editing	YES
6149366	30240121	ET	2	had key roles in designing the research study and managing the research data|were involved in the management of the field research|oversaw the clinic data collection and management, and helped resolve complex clinic data issues|contributed to writing up the methods section	had key roles in designing the research study and managing the research data	Conceived and designed the experiments	Methodology	YES
6149366	30240121	ET	2	had key roles in designing the research study and managing the research data|were involved in the management of the field research|oversaw the clinic data collection and management, and helped resolve complex clinic data issues|contributed to writing up the methods section	were involved in the management of the field research	-	-	NO
6149366	30240121	ET	2	had key roles in designing the research study and managing the research data|were involved in the management of the field research|oversaw the clinic data collection and management, and helped resolve complex clinic data issues|contributed to writing up the methods section	oversaw the clinic data collection and management, and helped resolve complex clinic data issues	Performed the experiments|Analyzed the data	Data curation|Investigation|Supervision	YES
6149366	30240121	ET	2	had key roles in designing the research study and managing the research data|were involved in the management of the field research|oversaw the clinic data collection and management, and helped resolve complex clinic data issues|contributed to writing up the methods section	contributed to writing up the methods section	Performed the experiments|Wrote the paper	Writing - Original Draft	YES
6149366	30240121	LC	2	had key roles in designing the research study and managing the research data|were involved in the management of the field research|took the lead in conceptualizing the paper and writing it up|conducted the analysis	had key roles in designing the research study and managing the research data	Conceived and designed the experiments	Methodology	YES
6149366	30240121	LC	2	had key roles in designing the research study and managing the research data|were involved in the management of the field research|took the lead in conceptualizing the paper and writing it up|conducted the analysis	were involved in the management of the field research	-	-	NO
6149366	30240121	LC	2	had key roles in designing the research study and managing the research data|were involved in the management of the field research|took the lead in conceptualizing the paper and writing it up|conducted the analysis	took the lead in conceptualizing the paper and writing it up	Conceived and designed the experiments|Wrote the paper	Conceptualization	YES
6149366	30240121	LC	2	had key roles in designing the research study and managing the research data|were involved in the management of the field research|took the lead in conceptualizing the paper and writing it up|conducted the analysis	conducted the analysis	Performed the experiments	Investigation	YES
6149366	30240121	LS	2	contributed to this research design and to the choice of measurement tools	contributed to this research design and to the choice of measurement tools	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
6149366	30240121	MC	2	were involved in the management of the field research|contributed to the literature reviews and provided conceptual input for the introduction and discussion sections	were involved in the management of the field research	-	-	NO
6149366	30240121	MC	2	were involved in the management of the field research|contributed to the literature reviews and provided conceptual input for the introduction and discussion sections	contributed to the literature reviews and provided conceptual input for the introduction and discussion sections	Conceived and designed the experiments	Conceptualization|Formal analysis	YES
6149366	30240121	MO	2	conducted the analysis	conducted the analysis	Performed the experiments	Investigation	YES
6149366	30240121	MP	2	contributed to this research design and to the choice of measurement tools|were involved in the management of the field research|conducted the analysis	contributed to this research design and to the choice of measurement tools	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
6149366	30240121	MP	2	contributed to this research design and to the choice of measurement tools|were involved in the management of the field research|conducted the analysis	were involved in the management of the field research	-	-	NO
6149366	30240121	MP	2	contributed to this research design and to the choice of measurement tools|were involved in the management of the field research|conducted the analysis	conducted the analysis	Performed the experiments	Investigation	YES
6149366	30240121	NB	2	were involved in the management of the field research|oversaw the clinic data collection and management, and helped resolve complex clinic data issues	were involved in the management of the field research	-	-	NO
6149366	30240121	NB	2	were involved in the management of the field research|oversaw the clinic data collection and management, and helped resolve complex clinic data issues	oversaw the clinic data collection and management, and helped resolve complex clinic data issues	Performed the experiments|Analyzed the data	Data curation|Investigation|Supervision	YES
4409391	25909456	BA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409391	25909456	BA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409391	25909456	BA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409391	25909456	BA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409391	25909456	BA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409391	25909456	DL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409391	25909456	MAF	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409391	25909456	MBG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409391	25909456	MKD	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409391	25909456	MKD	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409391	25909456	RAG	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4409391	25909456	RAG	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409391	25909456	SA	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409391	25909456	SA	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409391	25909456	SY	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4409391	25909456	SY	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409391	25909456	WZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409391	25909456	WZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409391	25909456	WZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5644266	29075281	AR	2	conceived of and designed the study|managed and inoculated the experimental plants, collected samples, prepared cdna, performed the qpcr analysis, prepared samples for hplc and wrote the manuscript	conceived of and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5644266	29075281	AR	2	conceived of and designed the study|managed and inoculated the experimental plants, collected samples, prepared cdna, performed the qpcr analysis, prepared samples for hplc and wrote the manuscript	managed and inoculated the experimental plants, collected samples, prepared cdna, performed the qpcr analysis, prepared samples for hplc and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5644266	29075281	GY	2	assisted with the cdna preparation and qpcr analysis	assisted with the cdna preparation and qpcr analysis	Performed the experiments	Investigation	YES
5644266	29075281	HK	2	conducted the hplc analysis	conducted the hplc analysis	Performed the experiments	Investigation	YES
5644266	29075281	IN	2	conceived of and designed the study	conceived of and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5644266	29075281	JP	2	conceived of and designed the study	conceived of and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5644266	29075281	MH	2	carefully commented on a draft of the manuscript	carefully commented on a draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
5644266	29075281	RL	2	assisted with the cdna preparation and qpcr analysis	assisted with the cdna preparation and qpcr analysis	Performed the experiments	Investigation	YES
4650014	26574523	G.F.	4	which was updated and refined by	which was updated and refined by	-	-	NO
1794165	17311097	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1794165	17311097	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1794165	17311097	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1794165	17311097	GZ	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1794165	17311097	GZ	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1794165	17311097	RM	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1794165	17311097	TJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1794165	17311097	TJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1794165	17311097	TJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1794165	17311097	YB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4480261	26130918	Ashima Nehra	7	Carried out the initial assessment and interventions given to the patient and the family along with the compilation of the article	Carried out the initial assessment and interventions given to the patient and the family along with the compilation of the article	Performed the experiments	Investigation	YES
4480261	26130918	Harsimarpreet Kaur	7	Helped in the post assessment and compilation of the article	Helped in the post assessment and compilation of the article	-	-	NO
5463356	28592307	AL	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5463356	28592307	CR	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5463356	28592307	JM	PLoS52	analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
5463356	28592307	PYR	PLoS52	conceived and supervised the study|analysed the data|wrote the paper	conceived and supervised the study	Conceived and designed the experiments	Conceptualization|Supervision	YES
5463356	28592307	PYR	PLoS52	conceived and supervised the study|analysed the data|wrote the paper	analysed the data	Analyzed the data	Formal analysis	YES
5463356	28592307	PYR	PLoS52	conceived and supervised the study|analysed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4556830	26357656	Jinzhang Cai	2	contributed equally to this work	contributed equally to this work	-	-	NO
4556830	26357656	Qingwei Zhang	2	contributed equally to this work	contributed equally to this work	-	-	NO
4409392	25909194	ALC	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409392	25909194	ALC	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409392	25909194	ALC	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409392	25909194	ALC	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409392	25909194	CHL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409392	25909194	CHL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409392	25909194	CHL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409392	25909194	CHL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409392	25909194	CHL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409392	25909194	CHY	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409392	25909194	CHY	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4409392	25909194	CHY	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409392	25909194	CJC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409392	25909194	CNH	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409392	25909194	CSH	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409392	25909194	CYS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409392	25909194	CYS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409392	25909194	CYS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409392	25909194	CYS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409392	25909194	CYS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409392	25909194	DYC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409392	25909194	ICC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409392	25909194	JHL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409392	25909194	JHL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409392	25909194	JHL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409392	25909194	KTK	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409392	25909194	PFW	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409392	25909194	SHK	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409392	25909194	WHK	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409392	25909194	WWC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409392	25909194	YSL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409392	25909194	YSL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409392	25909194	YSL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409392	25909194	YSL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5463365	28595602	KO	1	Study design	Study design	Conceived and designed the experiments	Methodology	YES
5463365	28595602	RR	1	Study design	Study design	Conceived and designed the experiments	Methodology	YES
6173277	30289626	All authors	2	participated in research think tanks where ideas presented in the viewpoint were discussed, and revised and approved the text	participated in research think tanks where ideas presented in the viewpoint were discussed, and revised and approved the text	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
1794166	17311098	AV	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1794166	17311098	CG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1794166	17311098	FT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1794166	17311098	FT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1794166	17311098	FT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1794166	17311098	NT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1794166	17311098	NT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1794166	17311098	NT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1794166	17311098	NT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4650015	26574527	J.A.B.	2	contributed equally to the preparation of this review and both gave final approval for publication	contributed equally to the preparation of this review and both gave final approval for publication	-	-	NO
4650015	26574527	P.N.B.	2	contributed equally to the preparation of this review and both gave final approval for publication	contributed equally to the preparation of this review and both gave final approval for publication	-	-	NO
5644281	29075283	AFL	2	critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5644281	29075283	AL	2	contributed for writing and editing the major part of the review and was involved in approving the final version of the review	contributed for writing and editing the major part of the review and was involved in approving the final version of the review	Wrote the paper	Writing - Review & Editing	YES
5644281	29075283	AM	2	contributed to the design of this work outlay and was responsible for drafting the manuscript and final approval from all others	contributed to the design of this work outlay and was responsible for drafting the manuscript and final approval from all others	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
5644281	29075283	LS	2	organized and prepared some of the parts of this review	organized and prepared some of the parts of this review	-	-	NO
5644281	29075283	VB	2	organized and prepared some of the parts of this review	organized and prepared some of the parts of this review	-	-	NO
5644281	29075283	VM	2	organized and prepared some of the parts of this review	organized and prepared some of the parts of this review	-	-	NO
4481547	26130922	A Akanmu	7	interpretation of data, supervision of the entire study and drafting of manuscript	interpretation of data, supervision of the entire study and drafting of manuscript	Analyzed the data|Wrote the paper	Formal analysis|Supervision|Writing - Original Draft	YES
4481547	26130922	Adejoke Onaolapo Adejoke	7	Were also responsible for the collection, collation and analysis of data, interpretation of results and drafting of manuscript. Also responsible for the care of animals, Moses	Were also responsible for the collection, collation and analysis of data, interpretation of results and drafting of manuscript. Also responsible for the care of animals, Moses	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4481547	26130922	Gbola Olayiwola	7	interpretation of data, supervision of the entire study and drafting of manuscript	interpretation of data, supervision of the entire study and drafting of manuscript	Analyzed the data|Wrote the paper	Formal analysis|Supervision|Writing - Original Draft	YES
4481547	26130922	J Onaolapo	7	Were also responsible for the collection, collation and analysis of data, interpretation of results and drafting of manuscript. Also responsible for the care of animals, Moses	Were also responsible for the collection, collation and analysis of data, interpretation of results and drafting of manuscript. Also responsible for the care of animals, Moses	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4481547	26130922	Y Onaolapo	7	Conceived and designed the work that led to the submission, Olakunle J|Were also responsible for the collection, collation and analysis of data, interpretation of results and drafting of manuscript. Also responsible for the care of animals, Moses	Conceived and designed the work that led to the submission, Olakunle J	Conceived and designed the experiments	Conceptualization	YES
4481547	26130922	Y Onaolapo	7	Conceived and designed the work that led to the submission, Olakunle J|Were also responsible for the collection, collation and analysis of data, interpretation of results and drafting of manuscript. Also responsible for the care of animals, Moses	Were also responsible for the collection, collation and analysis of data, interpretation of results and drafting of manuscript. Also responsible for the care of animals, Moses	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
1794168	17311099	CB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1794168	17311099	JH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4685761	26621985	The authors	2	contributed equally to the research reported in this paper	contributed equally to the research reported in this paper	-	-	NO
5644282	29075276	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5644282	29075276	CB	2	carried out the plant experiments, contributed to interpretation of data and drafted the manuscript	carried out the plant experiments, contributed to interpretation of data and drafted the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft	YES
5644282	29075276	GS	2	carried out the plant experiments, contributed to interpretation of data and drafted the manuscript	carried out the plant experiments, contributed to interpretation of data and drafted the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft	YES
5644282	29075276	JB	2	carried out the plant experiments, contributed to interpretation of data and drafted the manuscript	carried out the plant experiments, contributed to interpretation of data and drafted the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft	YES
5644282	29075276	JF	2	draft and critically revise the manuscript	draft and critically revise the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5644282	29075276	LB	2	carried out the plant experiments, contributed to interpretation of data and drafted the manuscript	carried out the plant experiments, contributed to interpretation of data and drafted the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft	YES
5644282	29075276	LL	2	developed the mass spectrometric method, performed statistics and helped to draft the manuscript	developed the mass spectrometric method, performed statistics and helped to draft the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5644282	29075276	MB	2	draft and critically revise the manuscript	draft and critically revise the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5644282	29075276	PR	2	draft and critically revise the manuscript	draft and critically revise the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5644282	29075276	SL	2	carried out the plant experiments, contributed to interpretation of data and drafted the manuscript	carried out the plant experiments, contributed to interpretation of data and drafted the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft	YES
6178281	30303293	All authors	2	contributed substantively to the writing of this manuscript and approved the final version	contributed substantively to the writing of this manuscript and approved the final version	Wrote the paper	Writing - Original Draft	YES
5463376	28592235	All authors	2	read, edited and approved the manuscript	read, edited and approved the manuscript	Wrote the paper	Writing - Review & Editing	YES
5463376	28592235	BJM	2	conceived and designed the study and advised on interpretation of the data throughout	conceived and designed the study and advised on interpretation of the data throughout	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
5463376	28592235	CP	2	advised on interpretation of the data for genetic linkage map construction in the specific cross	advised on interpretation of the data for genetic linkage map construction in the specific cross	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5463376	28592235	DJP	2	conceived and designed the study and advised on interpretation of the data throughout	conceived and designed the study and advised on interpretation of the data throughout	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
5463376	28592235	MO	2	as well as advising on interpretation of the data and on bioinformatics	as well as advising on interpretation of the data and on bioinformatics	Analyzed the data	Formal analysis	YES
4409393	25909600	GDL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409393	25909600	GDL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409393	25909600	GDL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409393	25909600	GDL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409393	25909600	JJL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409393	25909600	JJL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409393	25909600	JJL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409393	25909600	SLC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409393	25909600	SLC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409393	25909600	SLC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409393	25909600	SLC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409393	25909600	SPC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409393	25909600	SPC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409393	25909600	SPC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409393	25909600	SPC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409393	25909600	ST	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409393	25909600	ST	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1794186	17311100	AJ	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1794186	17311100	AJ	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1794186	17311100	SD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1794186	17311100	SD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1794186	17311100	SD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1794186	17311100	SD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4481550	26130928	A Sillay	2	contributed equally to prepare the manuscript	contributed equally to prepare the manuscript	Wrote the paper	Writing - Original Draft	YES
6186966	30318715	BGW	2	contributed equally to conceptualizing, developing arguments, producing and finalizing the final draft	contributed equally to conceptualizing, developing arguments, producing and finalizing the final draft	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
6186966	30318715	RG	2	contributed equally to conceptualizing, developing arguments, producing and finalizing the final draft	contributed equally to conceptualizing, developing arguments, producing and finalizing the final draft	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
6186966	30318715	SG	2	contributed equally to conceptualizing, developing arguments, producing and finalizing the final draft	contributed equally to conceptualizing, developing arguments, producing and finalizing the final draft	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5645499	29081784	AF	PLoS52	conceived and designed the experiments|analyzed the data|contributed reagents/materials/analysis tools|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5645499	29081784	AF	PLoS52	conceived and designed the experiments|analyzed the data|contributed reagents/materials/analysis tools|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5645499	29081784	AF	PLoS52	conceived and designed the experiments|analyzed the data|contributed reagents/materials/analysis tools|wrote the paper	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5645499	29081784	AF	PLoS52	conceived and designed the experiments|analyzed the data|contributed reagents/materials/analysis tools|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5645499	29081784	HY	PLoS52	contributed reagents/materials/analysis tools	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5645499	29081784	KN	PLoS52	performed the experiments|contributed reagents/materials/analysis tools	performed the experiments	Performed the experiments	Investigation	YES
5645499	29081784	KN	PLoS52	performed the experiments|contributed reagents/materials/analysis tools	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5645499	29081784	MA	PLoS52	conceived and designed the experiments|contributed reagents/materials/analysis tools	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5645499	29081784	MA	PLoS52	conceived and designed the experiments|contributed reagents/materials/analysis tools	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5645499	29081784	MK	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5645499	29081784	TK	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|contributed reagents/materials/analysis tools|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5645499	29081784	TK	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|contributed reagents/materials/analysis tools|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5645499	29081784	TK	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|contributed reagents/materials/analysis tools|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5645499	29081784	TK	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|contributed reagents/materials/analysis tools|wrote the paper	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5645499	29081784	TK	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|contributed reagents/materials/analysis tools|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5645499	29081784	YK	PLoS52	performed the experiments|contributed reagents/materials/analysis tools	performed the experiments	Performed the experiments	Investigation	YES
5645499	29081784	YK	PLoS52	performed the experiments|contributed reagents/materials/analysis tools	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5645499	29081784	YN	PLoS52	performed the experiments|contributed reagents/materials/analysis tools	performed the experiments	Performed the experiments	Investigation	YES
5645499	29081784	YN	PLoS52	performed the experiments|contributed reagents/materials/analysis tools	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4481551	26130924	A Akanmu	7	Interpretation of data, supervision of the entire study and drafting of manuscript	Interpretation of data, supervision of the entire study and drafting of manuscript	Analyzed the data|Wrote the paper	Formal analysis|Supervision|Writing - Original Draft	YES
4481551	26130924	Gbola Olayiwola	7	Interpretation of data, supervision of the entire study and drafting of manuscript	Interpretation of data, supervision of the entire study and drafting of manuscript	Analyzed the data|Wrote the paper	Formal analysis|Supervision|Writing - Original Draft	YES
4481551	26130924	J Onaolapo	7	Conceived and designed the work as a part of his Phd thesis, Olakunle J Onaolapo and Adejoke	Conceived and designed the work as a part of his Phd thesis, Olakunle J Onaolapo and Adejoke	Conceived and designed the experiments	Conceptualization	YES
4481551	26130924	Y Onaolapo	7	Responsible for the care of animals, collection, collation and analysis of data, and drafting of manuscript, Moses	Responsible for the care of animals, collection, collation and analysis of data, and drafting of manuscript, Moses	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4685966	26667907	J.P.	2	conceived of the study|drafted the manuscript and agreed the final publication	conceived of the study	Conceived and designed the experiments	Conceptualization	YES
4685966	26667907	J.P.	2	conceived of the study|drafted the manuscript and agreed the final publication	drafted the manuscript and agreed the final publication	Wrote the paper	Writing - Original Draft	YES
4685966	26667907	S.M.	2	drafted the manuscript and agreed the final publication	drafted the manuscript and agreed the final publication	Wrote the paper	Writing - Original Draft	YES
4409394	25909811	HXJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409394	25909811	HXJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409394	25909811	HXJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409394	25909811	MLG	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409394	25909811	PY	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4409394	25909811	PZ	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409394	25909811	XJY	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409394	25909811	XTQ	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5465472	28595635	BCL	PLoS52	performed the research|analysed the data|wrote the paper	performed the research	Performed the experiments	Investigation	YES
5465472	28595635	BCL	PLoS52	performed the research|analysed the data|wrote the paper	analysed the data	Analyzed the data	Formal analysis	YES
5465472	28595635	BCL	PLoS52	performed the research|analysed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5465472	28595635	HC	PLoS52	performed the research|analysed the data|wrote the paper	performed the research	Performed the experiments	Investigation	YES
5465472	28595635	HC	PLoS52	performed the research|analysed the data|wrote the paper	analysed the data	Analyzed the data	Formal analysis	YES
5465472	28595635	HC	PLoS52	performed the research|analysed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5465472	28595635	SLK	PLoS52	performed the research|analysed the data|wrote the paper	performed the research	Performed the experiments	Investigation	YES
5465472	28595635	SLK	PLoS52	performed the research|analysed the data|wrote the paper	analysed the data	Analyzed the data	Formal analysis	YES
5465472	28595635	SLK	PLoS52	performed the research|analysed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5465472	28595635	SMK	PLoS52	performed the research|analysed the data|wrote the paper	performed the research	Performed the experiments	Investigation	YES
5465472	28595635	SMK	PLoS52	performed the research|analysed the data|wrote the paper	analysed the data	Analyzed the data	Formal analysis	YES
5465472	28595635	SMK	PLoS52	performed the research|analysed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5465472	28595635	WKC	PLoS52	designed the research|analysed the data|wrote the paper	designed the research	Conceived and designed the experiments	Methodology	YES
5465472	28595635	WKC	PLoS52	designed the research|analysed the data|wrote the paper	analysed the data	Analyzed the data	Formal analysis	YES
5465472	28595635	WKC	PLoS52	designed the research|analysed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5465472	28595635	YJ	PLoS52	designed the research|performed the research|analysed the data|wrote the paper	designed the research	Conceived and designed the experiments	Methodology	YES
5465472	28595635	YJ	PLoS52	designed the research|performed the research|analysed the data|wrote the paper	performed the research	Performed the experiments	Investigation	YES
5465472	28595635	YJ	PLoS52	designed the research|performed the research|analysed the data|wrote the paper	analysed the data	Analyzed the data	Formal analysis	YES
5465472	28595635	YJ	PLoS52	designed the research|performed the research|analysed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6186967	30318851	DJW	2	equally contributed to this response, supported with edits from the optima hiv study team	equally contributed to this response, supported with edits from the optima hiv study team	Wrote the paper	Writing - Review & Editing	YES
6186967	30318851	DPW	2	equally contributed to this response, supported with edits from the optima hiv study team	equally contributed to this response, supported with edits from the optima hiv study team	Wrote the paper	Writing - Review & Editing	YES
6186967	30318851	MG	2	equally contributed to this response, supported with edits from the optima hiv study team	equally contributed to this response, supported with edits from the optima hiv study team	Wrote the paper	Writing - Review & Editing	YES
1794193	17311101	AV	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1794193	17311101	MA	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1794193	17311101	MA	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1794193	17311101	MA	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1794193	17311101	NP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1794193	17311101	NP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1794193	17311101	NP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1794193	17311101	NP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1794193	17311101	RD	PLoS5	Center	Center	-	-	NO
1794193	17311101	ST	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5645508	29081783	FZ	2	performed experiments, analyzed and interpreted the data, and wrote the manuscript	performed experiments, analyzed and interpreted the data, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5645508	29081783	HG	2	revised the manuscript critically	revised the manuscript critically	Wrote the paper	Writing - Review & Editing	YES
5645508	29081783	JY	2	revised the manuscript critically|performed experiments, analyzed and interpreted the data, and wrote the manuscript	revised the manuscript critically	Wrote the paper	Writing - Review & Editing	YES
5645508	29081783	JY	2	revised the manuscript critically|performed experiments, analyzed and interpreted the data, and wrote the manuscript	performed experiments, analyzed and interpreted the data, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5645508	29081783	LY	2	designed the study|revised the manuscript critically|performed experiments, analyzed and interpreted the data, and wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5645508	29081783	LY	2	designed the study|revised the manuscript critically|performed experiments, analyzed and interpreted the data, and wrote the manuscript	revised the manuscript critically	Wrote the paper	Writing - Review & Editing	YES
5645508	29081783	LY	2	designed the study|revised the manuscript critically|performed experiments, analyzed and interpreted the data, and wrote the manuscript	performed experiments, analyzed and interpreted the data, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5645508	29081783	RT	2	designed the study|performed experiments, analyzed and interpreted the data, and wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5645508	29081783	RT	2	designed the study|performed experiments, analyzed and interpreted the data, and wrote the manuscript	performed experiments, analyzed and interpreted the data, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5645508	29081783	SL	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5645508	29081783	WL	2	revised the manuscript critically	revised the manuscript critically	Wrote the paper	Writing - Review & Editing	YES
5645508	29081783	XW	2	performed experiments, analyzed and interpreted the data, and wrote the manuscript	performed experiments, analyzed and interpreted the data, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5645508	29081783	YW	2	performed experiments, analyzed and interpreted the data, and wrote the manuscript	performed experiments, analyzed and interpreted the data, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6186968	30318848	AM	2	conducted the analysis|prepared the original draft|reviewed and edited the draft	conducted the analysis	Performed the experiments	Investigation	YES
6186968	30318848	AM	2	conducted the analysis|prepared the original draft|reviewed and edited the draft	prepared the original draft	Wrote the paper	Writing - Original Draft	YES
6186968	30318848	AM	2	conducted the analysis|prepared the original draft|reviewed and edited the draft	reviewed and edited the draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6186968	30318848	ANH	2	prepared the original draft|reviewed and edited the draft	prepared the original draft	Wrote the paper	Writing - Original Draft	YES
6186968	30318848	ANH	2	prepared the original draft|reviewed and edited the draft	reviewed and edited the draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6186968	30318848	CH	2	conceptualized the study|designed the study|conducted the analysis|prepared the original draft|reviewed and edited the draft	conceptualized the study	Conceived and designed the experiments	Conceptualization	YES
6186968	30318848	CH	2	conceptualized the study|designed the study|conducted the analysis|prepared the original draft|reviewed and edited the draft	designed the study	Conceived and designed the experiments	Methodology	YES
6186968	30318848	CH	2	conceptualized the study|designed the study|conducted the analysis|prepared the original draft|reviewed and edited the draft	conducted the analysis	Performed the experiments	Investigation	YES
6186968	30318848	CH	2	conceptualized the study|designed the study|conducted the analysis|prepared the original draft|reviewed and edited the draft	prepared the original draft	Wrote the paper	Writing - Original Draft	YES
6186968	30318848	CH	2	conceptualized the study|designed the study|conducted the analysis|prepared the original draft|reviewed and edited the draft	reviewed and edited the draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6186968	30318848	LL	2	reviewed and edited the draft	reviewed and edited the draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6186968	30318848	MM	2	designed the study|reviewed and edited the draft	designed the study	Conceived and designed the experiments	Methodology	YES
6186968	30318848	MM	2	designed the study|reviewed and edited the draft	reviewed and edited the draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6186968	30318848	MPF	2	conceptualized the study|reviewed and edited the draft	conceptualized the study	Conceived and designed the experiments	Conceptualization	YES
6186968	30318848	MPF	2	conceptualized the study|reviewed and edited the draft	reviewed and edited the draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6186968	30318848	SF	2	reviewed and edited the draft	reviewed and edited the draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6186968	30318848	SP	2	designed the study|conducted the analysis|prepared the original draft	designed the study	Conceived and designed the experiments	Methodology	YES
6186968	30318848	SP	2	designed the study|conducted the analysis|prepared the original draft	conducted the analysis	Performed the experiments	Investigation	YES
6186968	30318848	SP	2	designed the study|conducted the analysis|prepared the original draft	prepared the original draft	Wrote the paper	Writing - Original Draft	YES
4409395	25909740	JL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409395	25909740	JL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409395	25909740	XL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409395	25909740	XL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409395	25909740	XL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409395	25909740	XL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409395	25909740	XL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409395	25909740	YW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409395	25909740	YW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4409395	25909740	YW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4409395	25909740	YW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4685967	26667913	All authors	2	contributed to the work presented in this paper, discussed the issues, options and implications, commented on the manuscript at all stages, and gave final approval for publication	contributed to the work presented in this paper, discussed the issues, options and implications, commented on the manuscript at all stages, and gave final approval for publication	-	-	NO
5645512	29081782	AL	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5645512	29081782	EA	PLoS52	helped to revise the manuscript	helped to revise the manuscript	Wrote the paper	Writing - Review & Editing	YES
5645512	29081782	HS	PLoS52	helped to revise the manuscript	helped to revise the manuscript	Wrote the paper	Writing - Review & Editing	YES
5645512	29081782	JF	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5645512	29081782	LC	PLoS52	conceived and designed the experiments|analyzed the data|helped to revise the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5645512	29081782	LC	PLoS52	conceived and designed the experiments|analyzed the data|helped to revise the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5645512	29081782	LC	PLoS52	conceived and designed the experiments|analyzed the data|helped to revise the manuscript	helped to revise the manuscript	Wrote the paper	Writing - Review & Editing	YES
5645512	29081782	XH	PLoS52	analyzed the data|performed the experiments and wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5645512	29081782	XH	PLoS52	analyzed the data|performed the experiments and wrote the manuscript	performed the experiments and wrote the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5645512	29081782	ZH	PLoS52	analyzed the data|helped to revise the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5645512	29081782	ZH	PLoS52	analyzed the data|helped to revise the manuscript	helped to revise the manuscript	Wrote the paper	Writing - Review & Editing	YES
1794318	17297505	CK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1794318	17297505	CK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1794318	17297505	CK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1794318	17297505	CK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1794318	17297505	CL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1794318	17297505	CL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1794318	17297505	CL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1794318	17297505	CL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1794318	17297505	KL	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1794318	17297505	SL	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1794318	17297505	TW	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1794318	17297505	YC	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4481553	26130926	Anjana Talwar	7	Concept and design of study, critical important revision	Concept and design of study, critical important revision	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
4481553	26130926	Jayvardhan Singh	7	Drafting of article	Drafting of article	Wrote the paper	Writing - Original Draft	YES
4481553	26130926	Ratna Sharma	7	Concept and design of study and interpretation	Concept and design of study and interpretation	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
4481553	26130926	Yogesh Singh	7	Design of study, Acquisition, Interpretation and Drafting	Design of study, Acquisition, Interpretation and Drafting	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5465539	28595568	ADZ	2	contributed to bioinformatics analysis and wrote the manuscript	contributed to bioinformatics analysis and wrote the manuscript	Wrote the paper	Formal analysis|Writing - Original Draft	YES
5465539	28595568	LBH	2	contributed to bioinformatics analysis and wrote the manuscript|participated in primers design and rt-qpcr analysis	contributed to bioinformatics analysis and wrote the manuscript	Wrote the paper	Formal analysis|Writing - Original Draft	YES
5465539	28595568	LBH	2	contributed to bioinformatics analysis and wrote the manuscript|participated in primers design and rt-qpcr analysis	participated in primers design and rt-qpcr analysis	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5465539	28595568	LJL	2	performed sample collection and rna isolation	performed sample collection and rna isolation	Performed the experiments	Investigation	YES
5465539	28595568	PFC	2	participated in primers design and rt-qpcr analysis	participated in primers design and rt-qpcr analysis	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5465539	28595568	RH	2	performed sample collection and rna isolation	performed sample collection and rna isolation	Performed the experiments	Investigation	YES
5465539	28595568	YML	2	performed sample collection and rna isolation	performed sample collection and rna isolation	Performed the experiments	Investigation	YES
5465539	28595568	YPW	2	contributed to the design of the research and manuscript editing	contributed to the design of the research and manuscript editing	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5465539	28595568	YYP	2	participated in primers design and rt-qpcr analysis	participated in primers design and rt-qpcr analysis	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5465539	28595568	ZYZ	2	contributed to the design of the research and manuscript editing	contributed to the design of the research and manuscript editing	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
6192462	28872276	AC	7	study design|writing	study design	Conceived and designed the experiments	Methodology	YES
6192462	28872276	AC	7	study design|writing	writing	Wrote the paper	-	YES
6192462	28872276	AHM	7	data collection|data interpretation and analysis|writing	data collection	Performed the experiments	Investigation	YES
6192462	28872276	AHM	7	data collection|data interpretation and analysis|writing	data interpretation and analysis	Analyzed the data	Formal analysis	YES
6192462	28872276	AHM	7	data collection|data interpretation and analysis|writing	writing	Wrote the paper	-	YES
6192462	28872276	CTT	7	study design|data interpretation and analysis|writing	study design	Conceived and designed the experiments	Methodology	YES
6192462	28872276	CTT	7	study design|data interpretation and analysis|writing	data interpretation and analysis	Analyzed the data	Formal analysis	YES
6192462	28872276	CTT	7	study design|data interpretation and analysis|writing	writing	Wrote the paper	-	YES
6192462	28872276	EJA	7	study design|data interpretation and analysis|writing	study design	Conceived and designed the experiments	Methodology	YES
6192462	28872276	EJA	7	study design|data interpretation and analysis|writing	data interpretation and analysis	Analyzed the data	Formal analysis	YES
6192462	28872276	EJA	7	study design|data interpretation and analysis|writing	writing	Wrote the paper	-	YES
6192462	28872276	FP	7	data collection|data interpretation and analysis|writing	data collection	Performed the experiments	Investigation	YES
6192462	28872276	FP	7	data collection|data interpretation and analysis|writing	data interpretation and analysis	Analyzed the data	Formal analysis	YES
6192462	28872276	FP	7	data collection|data interpretation and analysis|writing	writing	Wrote the paper	-	YES
6192462	28872276	GGS	7	study design|data interpretation and analysis|writing	study design	Conceived and designed the experiments	Methodology	YES
6192462	28872276	GGS	7	study design|data interpretation and analysis|writing	data interpretation and analysis	Analyzed the data	Formal analysis	YES
6192462	28872276	GGS	7	study design|data interpretation and analysis|writing	writing	Wrote the paper	-	YES
6192462	28872276	KT	7	study design|data collection|data interpretation and analysis|writing	study design	Conceived and designed the experiments	Methodology	YES
6192462	28872276	KT	7	study design|data collection|data interpretation and analysis|writing	data collection	Performed the experiments	Investigation	YES
6192462	28872276	KT	7	study design|data collection|data interpretation and analysis|writing	data interpretation and analysis	Analyzed the data	Formal analysis	YES
6192462	28872276	KT	7	study design|data collection|data interpretation and analysis|writing	writing	Wrote the paper	-	YES
6192462	28872276	LH	7	data collection|data interpretation and analysis|writing	data collection	Performed the experiments	Investigation	YES
6192462	28872276	LH	7	data collection|data interpretation and analysis|writing	data interpretation and analysis	Analyzed the data	Formal analysis	YES
6192462	28872276	LH	7	data collection|data interpretation and analysis|writing	writing	Wrote the paper	-	YES
6192462	28872276	LK	7	study design|data interpretation and analysis|writing	study design	Conceived and designed the experiments	Methodology	YES
6192462	28872276	LK	7	study design|data interpretation and analysis|writing	data interpretation and analysis	Analyzed the data	Formal analysis	YES
6192462	28872276	LK	7	study design|data interpretation and analysis|writing	writing	Wrote the paper	-	YES
6192462	28872276	MC	7	data collection|writing	data collection	Performed the experiments	Investigation	YES
6192462	28872276	MC	7	data collection|writing	writing	Wrote the paper	-	YES
6192462	28872276	NM	7	data collection|writing	data collection	Performed the experiments	Investigation	YES
6192462	28872276	NM	7	data collection|writing	writing	Wrote the paper	-	YES
6192462	28872276	PMM	7	data interpretation and analysis|writing	data interpretation and analysis	Analyzed the data	Formal analysis	YES
6192462	28872276	PMM	7	data interpretation and analysis|writing	writing	Wrote the paper	-	YES
6192462	28872276	RS	7	study design|data collection|data interpretation and analysis|writing	study design	Conceived and designed the experiments	Methodology	YES
6192462	28872276	RS	7	study design|data collection|data interpretation and analysis|writing	data collection	Performed the experiments	Investigation	YES
6192462	28872276	RS	7	study design|data collection|data interpretation and analysis|writing	data interpretation and analysis	Analyzed the data	Formal analysis	YES
6192462	28872276	RS	7	study design|data collection|data interpretation and analysis|writing	writing	Wrote the paper	-	YES
6192462	28872276	SS	7	data interpretation and analysis|writing	data interpretation and analysis	Analyzed the data	Formal analysis	YES
6192462	28872276	SS	7	data interpretation and analysis|writing	writing	Wrote the paper	-	YES
4409397	25909192	BR	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409397	25909192	HS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409397	25909192	HS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409397	25909192	JC	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409397	25909192	MK	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409397	25909192	NW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409397	25909192	NW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409397	25909192	NW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409397	25909192	PS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409397	25909192	PS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409397	25909192	PS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409397	25909192	RL	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409397	25909192	RL	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409397	25909192	SA	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409397	25909192	SB	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409397	25909192	SB	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409397	25909192	SKK	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409397	25909192	SS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4409397	25909192	SS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409397	25909192	TAS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409397	25909192	TAS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409397	25909192	TAS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409397	25909192	UCMN	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409397	25909192	UCMN	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409397	25909192	VKS	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4556865	26357650	Xiang Yu	2	contributed equally to this work and should be regarded as joint first authors	contributed equally to this work and should be regarded as joint first authors	-	-	NO
4556865	26357650	Yanfen Zou	2	contributed equally to this work and should be regarded as joint first authors	contributed equally to this work and should be regarded as joint first authors	-	-	NO
5645530	29081787	ER-G	2	were in charge of reviewing the writing	were in charge of reviewing the writing	Wrote the paper	-	YES
5645530	29081787	IM-B	2	were in charge of reviewing the writing	were in charge of reviewing the writing	Wrote the paper	-	YES
5645530	29081787	IT-P	2	was responsible for the work team and the conception of the research topic	was responsible for the work team and the conception of the research topic	Conceived and designed the experiments	Conceptualization	YES
5645530	29081787	LA-A	2	were in charge of reviewing the writing	were in charge of reviewing the writing	Wrote the paper	-	YES
5645530	29081787	MV-H	2	was responsible for reviewing of literature and writing the paper	was responsible for reviewing of literature and writing the paper	Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5645530	29081787	RG-G	2	the conception of the research topic and reviewing of the literature	the conception of the research topic and reviewing of the literature	Conceived and designed the experiments	Conceptualization|Formal analysis	YES
5645530	29081787	RO-V	2	were in charge of reviewing the writing	were in charge of reviewing the writing	Wrote the paper	-	YES
5645530	29081787	SR-G	2	were in charge of reviewing the writing	were in charge of reviewing the writing	Wrote the paper	-	YES
4685968	26667914	A.M.L.B.	2	contributing specific sections	contributing specific sections	-	-	NO
4685968	26667914	All authors	2	planned the papers structure and content	planned the papers structure and content	Conceived and designed the experiments	Conceptualization	YES
4685968	26667914	N.R.	2	contributing specific sections	contributing specific sections	-	-	NO
4685968	26667914	all authors	2	contributed to revising the paper in light of referees advice	contributed to revising the paper in light of referees advice	Wrote the paper	Writing - Review & Editing	YES
1794319	17311102	DE	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1794319	17311102	DE	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1794319	17311102	DE	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1794319	17311102	ES	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1794319	17311102	ES	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1794319	17311102	ST	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1794319	17311102	ST	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1794319	17311102	TK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1794319	17311102	TK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1794319	17311102	TK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1794319	17311102	TK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1794319	17311102	YK	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4481555	26130930	Arunansu Talukdar	7	Critical revision of the article for important intellectual content, Partha pal|Final approval of the article	Critical revision of the article for important intellectual content, Partha pal	Wrote the paper	Writing - Review & Editing	YES
4481555	26130930	Arunansu Talukdar	7	Critical revision of the article for important intellectual content, Partha pal|Final approval of the article	Final approval of the article	-	-	NO
4481555	26130930	Chakraborty Subhasish Dey	7	Final approval of the article	Final approval of the article	-	-	NO
4481555	26130930	Partha Pal	7	Conception and design	Conception and design	Conceived and designed the experiments	Conceptualization	YES
4481555	26130930	Sayantan Ray	7	Conception and design|Drafting of the article|Analysis and interpretation of data|Critical revision of the article for important intellectual content, Partha pal	Conception and design	Conceived and designed the experiments	Conceptualization	YES
4481555	26130930	Sayantan Ray	7	Conception and design|Drafting of the article|Analysis and interpretation of data|Critical revision of the article for important intellectual content, Partha pal	Drafting of the article	Wrote the paper	Writing - Original Draft	YES
4481555	26130930	Sayantan Ray	7	Conception and design|Drafting of the article|Analysis and interpretation of data|Critical revision of the article for important intellectual content, Partha pal	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
4481555	26130930	Sayantan Ray	7	Conception and design|Drafting of the article|Analysis and interpretation of data|Critical revision of the article for important intellectual content, Partha pal	Critical revision of the article for important intellectual content, Partha pal	Wrote the paper	Writing - Review & Editing	YES
4481555	26130930	Sayantan Ray Sumit	7	Final approval of the article	Final approval of the article	-	-	NO
4481555	26130930	Subhasish Dey	7	Literature search	Literature search	-	Formal analysis	YES
4481555	26130930	Sumit Chakraborty	7	Analysis and interpretation of data|Critical revision of the article for important intellectual content, Partha pal	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
4481555	26130930	Sumit Chakraborty	7	Analysis and interpretation of data|Critical revision of the article for important intellectual content, Partha pal	Critical revision of the article for important intellectual content, Partha pal	Wrote the paper	Writing - Review & Editing	YES
4409398	25909631	DH	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409398	25909631	GCA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Designed the software used in analysis	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409398	25909631	GCA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Designed the software used in analysis	Performed the experiments	Performed the experiments	Investigation	YES
4409398	25909631	GCA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Designed the software used in analysis	Analyzed the data	Analyzed the data	Formal analysis	YES
4409398	25909631	GCA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Designed the software used in analysis	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409398	25909631	GCA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Designed the software used in analysis	Designed the software used in analysis	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
4409398	25909631	HM	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409398	25909631	HM	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409398	25909631	MS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409398	25909631	MSR	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4409398	25909631	MSR	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4409398	25909631	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409398	25909631	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409398	25909631	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409398	25909631	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409398	25909631	TR	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409398	25909631	TR	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5645531	29081786	BM	PLoS52	participated in the research and analyzed the data	participated in the research and analyzed the data	Analyzed the data	Formal analysis	YES
5645531	29081786	HG	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5645531	29081786	JZ	PLoS52	participated in the research and analyzed the data	participated in the research and analyzed the data	Analyzed the data	Formal analysis	YES
5645531	29081786	LG	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5645531	29081786	LH	PLoS52	conceived and designed the research|wrote the paper with contributions of all the authors	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5645531	29081786	LH	PLoS52	conceived and designed the research|wrote the paper with contributions of all the authors	wrote the paper with contributions of all the authors	Wrote the paper	Writing - Original Draft	YES
5645531	29081786	LT	PLoS52	participated in the research and analyzed the data	participated in the research and analyzed the data	Analyzed the data	Formal analysis	YES
5645531	29081786	PS	PLoS52	conceived and designed the research|performed the experiments|wrote the paper with contributions of all the authors	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5645531	29081786	PS	PLoS52	conceived and designed the research|performed the experiments|wrote the paper with contributions of all the authors	performed the experiments	Performed the experiments	Investigation	YES
5645531	29081786	PS	PLoS52	conceived and designed the research|performed the experiments|wrote the paper with contributions of all the authors	wrote the paper with contributions of all the authors	Wrote the paper	Writing - Original Draft	YES
5645531	29081786	TH	PLoS52	participated in the research and analyzed the data	participated in the research and analyzed the data	Analyzed the data	Formal analysis	YES
5645531	29081786	WG	PLoS52	conceived and designed the research|wrote the paper with contributions of all the authors	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5645531	29081786	WG	PLoS52	conceived and designed the research|wrote the paper with contributions of all the authors	wrote the paper with contributions of all the authors	Wrote the paper	Writing - Original Draft	YES
5645531	29081786	XW	PLoS52	performed the homology modeling and molecular docking	performed the homology modeling and molecular docking	Performed the experiments	Investigation|Methodology	YES
5645531	29081786	YT	PLoS52	participated in the research and analyzed the data	participated in the research and analyzed the data	Analyzed the data	Formal analysis	YES
5645531	29081786	YfZ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5645531	29081786	YjZ	PLoS52	participated in the research and analyzed the data	participated in the research and analyzed the data	Analyzed the data	Formal analysis	YES
5465541	28595569	BBZ	2	performed data analysis and qrt pcr|contributed to preparation of the manuscript	performed data analysis and qrt pcr	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5465541	28595569	BBZ	2	performed data analysis and qrt pcr|contributed to preparation of the manuscript	contributed to preparation of the manuscript	Wrote the paper	Writing - Original Draft	YES
5465541	28595569	CZX	2	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5465541	28595569	HLW	2	constructed the bc8f1 population and investigated plants fertility	constructed the bc8f1 population and investigated plants fertility	Performed the experiments	Investigation	YES
5465541	28595569	JFZ	2	aided in experiments design|contributed to preparation of the manuscript	aided in experiments design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5465541	28595569	JFZ	2	aided in experiments design|contributed to preparation of the manuscript	contributed to preparation of the manuscript	Wrote the paper	Writing - Original Draft	YES
5465541	28595569	JYW	2	designed the experiments|contributed to preparation of the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5465541	28595569	JYW	2	designed the experiments|contributed to preparation of the manuscript	contributed to preparation of the manuscript	Wrote the paper	Writing - Original Draft	YES
5465541	28595569	LPG	2	constructed the bc8f1 population and investigated plants fertility	constructed the bc8f1 population and investigated plants fertility	Performed the experiments	Investigation	YES
5465541	28595569	MZ	2	performed data analysis and qrt pcr|contributed to preparation of the manuscript	performed data analysis and qrt pcr	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5465541	28595569	MZ	2	performed data analysis and qrt pcr|contributed to preparation of the manuscript	contributed to preparation of the manuscript	Wrote the paper	Writing - Original Draft	YES
5465541	28595569	TXQ	2	constructed the bc8f1 population and investigated plants fertility	constructed the bc8f1 population and investigated plants fertility	Performed the experiments	Investigation	YES
5465541	28595569	XXZ	2	performed bioinformatics analysis|contributed to preparation of the manuscript	performed bioinformatics analysis	Performed the experiments	Formal analysis|Investigation	YES
5465541	28595569	XXZ	2	performed bioinformatics analysis|contributed to preparation of the manuscript	contributed to preparation of the manuscript	Wrote the paper	Writing - Original Draft	YES
4696073	26712639	B.C.	2	designed the study, helped to analyse the data and wrote the manuscript	designed the study, helped to analyse the data and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4696073	26712639	M.T.	2	conducted the experiments, analysed the data, helped draft the manuscript and helped design the study	conducted the experiments, analysed the data, helped draft the manuscript and helped design the study	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
6192897	30334377	AML	PLoS52	were responsible for data merging and management|led the analysis with|wrote the paper	were responsible for data merging and management	-	-	NO
6192897	30334377	AML	PLoS52	were responsible for data merging and management|led the analysis with|wrote the paper	led the analysis with	-	-	NO
6192897	30334377	AML	PLoS52	were responsible for data merging and management|led the analysis with|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6192897	30334377	AP	PLoS52	conceived this study|were responsible for hptn 068 design and implementation|were responsible for community mobilization study design and implementation	conceived this study	Conceived and designed the experiments	Conceptualization	YES
6192897	30334377	AP	PLoS52	conceived this study|were responsible for hptn 068 design and implementation|were responsible for community mobilization study design and implementation	were responsible for hptn 068 design and implementation	Conceived and designed the experiments|Performed the experiments	Investigation	YES
6192897	30334377	AP	PLoS52	conceived this study|were responsible for hptn 068 design and implementation|were responsible for community mobilization study design and implementation	were responsible for community mobilization study design and implementation	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6192897	30334377	AS	PLoS52	were responsible for hptn 068 design and implementation|were responsible for community mobilization study design and implementation	were responsible for hptn 068 design and implementation	Conceived and designed the experiments|Performed the experiments	Investigation	YES
6192897	30334377	AS	PLoS52	were responsible for hptn 068 design and implementation|were responsible for community mobilization study design and implementation	were responsible for community mobilization study design and implementation	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6192897	30334377	CM	PLoS52	were responsible for hptn 068 design and implementation|were responsible for community mobilization study design and implementation	were responsible for hptn 068 design and implementation	Conceived and designed the experiments|Performed the experiments	Investigation	YES
6192897	30334377	CM	PLoS52	were responsible for hptn 068 design and implementation|were responsible for community mobilization study design and implementation	were responsible for community mobilization study design and implementation	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6192897	30334377	DEG	PLoS52	were responsible for data merging and management|assisted with the led the analysis with	were responsible for data merging and management	-	-	NO
6192897	30334377	DEG	PLoS52	were responsible for data merging and management|assisted with the led the analysis with	assisted with the led the analysis with	-	-	NO
6192897	30334377	DP	PLoS52	were responsible for community mobilization study design and implementation	were responsible for community mobilization study design and implementation	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6192897	30334377	FXGO	PLoS52	were responsible for hptn 068 design and implementation|were responsible for community mobilization study design and implementation	were responsible for hptn 068 design and implementation	Conceived and designed the experiments|Performed the experiments	Investigation	YES
6192897	30334377	FXGO	PLoS52	were responsible for hptn 068 design and implementation|were responsible for community mobilization study design and implementation	were responsible for community mobilization study design and implementation	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6192897	30334377	JA	PLoS52	conceived this study|assisted with the led the analysis with	conceived this study	Conceived and designed the experiments	Conceptualization	YES
6192897	30334377	JA	PLoS52	conceived this study|assisted with the led the analysis with	assisted with the led the analysis with	-	-	NO
6192897	30334377	KK	PLoS52	conceived this study|were responsible for hptn 068 design and implementation|were responsible for community mobilization study design and implementation	conceived this study	Conceived and designed the experiments	Conceptualization	YES
6192897	30334377	KK	PLoS52	conceived this study|were responsible for hptn 068 design and implementation|were responsible for community mobilization study design and implementation	were responsible for hptn 068 design and implementation	Conceived and designed the experiments|Performed the experiments	Investigation	YES
6192897	30334377	KK	PLoS52	conceived this study|were responsible for hptn 068 design and implementation|were responsible for community mobilization study design and implementation	were responsible for community mobilization study design and implementation	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6192897	30334377	RGW	PLoS52	were responsible for hptn 068 design and implementation|were responsible for community mobilization study design and implementation	were responsible for hptn 068 design and implementation	Conceived and designed the experiments|Performed the experiments	Investigation	YES
6192897	30334377	RGW	PLoS52	were responsible for hptn 068 design and implementation|were responsible for community mobilization study design and implementation	were responsible for community mobilization study design and implementation	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6192897	30334377	RT	PLoS52	were responsible for hptn 068 design and implementation|were responsible for community mobilization study design and implementation	were responsible for hptn 068 design and implementation	Conceived and designed the experiments|Performed the experiments	Investigation	YES
6192897	30334377	RT	PLoS52	were responsible for hptn 068 design and implementation|were responsible for community mobilization study design and implementation	were responsible for community mobilization study design and implementation	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6192897	30334377	SAL	PLoS52	conceived this study|were responsible for community mobilization study design and implementation|assisted with the led the analysis with|wrote the paper	conceived this study	Conceived and designed the experiments	Conceptualization	YES
6192897	30334377	SAL	PLoS52	conceived this study|were responsible for community mobilization study design and implementation|assisted with the led the analysis with|wrote the paper	were responsible for community mobilization study design and implementation	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6192897	30334377	SAL	PLoS52	conceived this study|were responsible for community mobilization study design and implementation|assisted with the led the analysis with|wrote the paper	assisted with the led the analysis with	-	-	NO
6192897	30334377	SAL	PLoS52	conceived this study|were responsible for community mobilization study design and implementation|assisted with the led the analysis with|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6192897	30334377	SMT	PLoS52	were responsible for hptn 068 design and implementation|were responsible for community mobilization study design and implementation	were responsible for hptn 068 design and implementation	Conceived and designed the experiments|Performed the experiments	Investigation	YES
6192897	30334377	SMT	PLoS52	were responsible for hptn 068 design and implementation|were responsible for community mobilization study design and implementation	were responsible for community mobilization study design and implementation	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6192897	30334377	TBN	PLoS52	conceived this study|assisted with the led the analysis with	conceived this study	Conceived and designed the experiments	Conceptualization	YES
6192897	30334377	TBN	PLoS52	conceived this study|assisted with the led the analysis with	assisted with the led the analysis with	-	-	NO
1794595	17311103	AG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1794595	17311103	AS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1794595	17311103	DS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1794595	17311103	DS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1794595	17311103	JB	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1794595	17311103	JB	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1794595	17311103	JM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1794595	17311103	KH	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1794595	17311103	RK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1794595	17311103	RK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1794595	17311103	RK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1794595	17311103	RK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1794595	17311103	RT	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1794595	17311103	SB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1794595	17311103	SU	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1794595	17311103	SU	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1794595	17311103	SU	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1794595	17311103	SU	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1794595	17311103	WR	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5645754	29081788	All authors	2	listed have made a substantial, direct and intellectual contribution to the work, and approved it for publication	listed have made a substantial, direct and intellectual contribution to the work, and approved it for publication	-	-	NO
4481556	26130923	All	2	contributed in the implementation of the research, analysis of results and report writing	contributed in the implementation of the research, analysis of results and report writing	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation	YES
4696074	26712640	All authors	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4696074	26712640	J.M.R.	2	conceived of and designed the study	conceived of and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4696074	26712640	K.R.	2	carried out the simulations and developed the necessary code|performed the data analysis|conceived of and designed the study	carried out the simulations and developed the necessary code	Performed the experiments	Formal analysis|Investigation|Software	YES
4696074	26712640	K.R.	2	carried out the simulations and developed the necessary code|performed the data analysis|conceived of and designed the study	performed the data analysis	Analyzed the data	Formal analysis	YES
4696074	26712640	K.R.	2	carried out the simulations and developed the necessary code|performed the data analysis|conceived of and designed the study	conceived of and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4696074	26712640	M.K.B.	2	performed the data analysis	performed the data analysis	Analyzed the data	Formal analysis	YES
4696074	26712640	N.J.M.	2	performed the data analysis|conceived of and designed the study	performed the data analysis	Analyzed the data	Formal analysis	YES
4696074	26712640	N.J.M.	2	performed the data analysis|conceived of and designed the study	conceived of and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5465549	28595570	C.R.	2	designed the experiments|performed motifs identification and led studies of protein modeling	designed the experiments	Conceived and designed the experiments	Methodology	YES
5465549	28595570	C.R.	2	designed the experiments|performed motifs identification and led studies of protein modeling	performed motifs identification and led studies of protein modeling	Performed the experiments	Investigation|Methodology	YES
5465549	28595570	F.P.	2	performed phylogenetic tree, qrt pcr experiments, analyzed efp browser data and assisted with motifs identification	performed phylogenetic tree, qrt pcr experiments, analyzed efp browser data and assisted with motifs identification	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5465549	28595570	J.P.	2	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5645755	29081789	CL	2	measured npq values	measured npq values	Performed the experiments	Investigation	YES
5645755	29081789	GW	2	designed the study and analyzed the data|wrote the manuscript	designed the study and analyzed the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5645755	29081789	GW	2	designed the study and analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5645755	29081789	HZ	2	performed gwas	performed gwas	Performed the experiments	Investigation	YES
5645755	29081789	JJ	2	performed genotypic assay in qtl mapping	performed genotypic assay in qtl mapping	Performed the experiments	Investigation	YES
5645755	29081789	JX	2	performed genotypic assay in qtl mapping	performed genotypic assay in qtl mapping	Performed the experiments	Investigation	YES
5645755	29081789	QW	2	carried out most of the experiments and analyzed the data|wrote the manuscript	carried out most of the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5645755	29081789	QW	2	carried out most of the experiments and analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5645755	29081789	WX	2	performed gwas	performed gwas	Performed the experiments	Investigation	YES
5645755	29081789	XF	2	measured npq values	measured npq values	Performed the experiments	Investigation	YES
5645755	29081789	YH	2	assisted in the construction of mapping populations	assisted in the construction of mapping populations	Performed the experiments	Investigation	YES
1794596	17311104	AK	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Improved the paper with comments	Performed the experiments	Performed the experiments	Investigation	YES
1794596	17311104	AK	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Improved the paper with comments	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1794596	17311104	AK	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Improved the paper with comments	Improved the paper with comments	Wrote the paper	Writing - Review & Editing	YES
1794596	17311104	CB	PLoS5	Contributed reagents/materials/analysis tools|Improved the paper with comments	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1794596	17311104	CB	PLoS5	Contributed reagents/materials/analysis tools|Improved the paper with comments	Improved the paper with comments	Wrote the paper	Writing - Review & Editing	YES
1794596	17311104	DH	PLoS5	Contributed reagents/materials/analysis tools|Improved the paper with comments	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1794596	17311104	DH	PLoS5	Contributed reagents/materials/analysis tools|Improved the paper with comments	Improved the paper with comments	Wrote the paper	Writing - Review & Editing	YES
1794596	17311104	JF	PLoS5	Contributed reagents/materials/analysis tools|Improved the paper with comments	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1794596	17311104	JF	PLoS5	Contributed reagents/materials/analysis tools|Improved the paper with comments	Improved the paper with comments	Wrote the paper	Writing - Review & Editing	YES
1794596	17311104	JP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1794596	17311104	JP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1794596	17311104	JP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1794596	17311104	JP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1794596	17311104	JP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1794596	17311104	JS	PLoS5	Contributed reagents/materials/analysis tools|Improved the paper with comments	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1794596	17311104	JS	PLoS5	Contributed reagents/materials/analysis tools|Improved the paper with comments	Improved the paper with comments	Wrote the paper	Writing - Review & Editing	YES
1794596	17311104	JW	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Improved the paper with comments	Performed the experiments	Performed the experiments	Investigation	YES
1794596	17311104	JW	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Improved the paper with comments	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1794596	17311104	JW	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Improved the paper with comments	Improved the paper with comments	Wrote the paper	Writing - Review & Editing	YES
1794596	17311104	OH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Improved the paper with comments	Performed the experiments	Performed the experiments	Investigation	YES
1794596	17311104	OH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Improved the paper with comments	Analyzed the data	Analyzed the data	Formal analysis	YES
1794596	17311104	OH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Improved the paper with comments	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1794596	17311104	OH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Improved the paper with comments	Improved the paper with comments	Wrote the paper	Writing - Review & Editing	YES
1794596	17311104	SB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Improved the paper with comments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1794596	17311104	SB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Improved the paper with comments	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1794596	17311104	SB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Improved the paper with comments	Improved the paper with comments	Wrote the paper	Writing - Review & Editing	YES
6192898	30334379	The authors	2	contributed equally to the conceptualization, writing and editing of this article	contributed equally to the conceptualization, writing and editing of this article	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
4558421	26366420	Jolanta Kiewisz	2	equally contributed to this paper	equally contributed to this paper	-	-	NO
4558421	26366420	Tomasz Wasniewski	2	equally contributed to this paper	equally contributed to this paper	-	-	NO
4481557	26130925	GP	7	Involved in the data interpretation and manuscript preparation	Involved in the data interpretation and manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4481557	26130925	R Kannan	7	Designed the objectives, Rajaretinam|Carried out the experiments, Samuel|Involved in the data interpretation and manuscript preparation	Designed the objectives, Rajaretinam	Conceived and designed the experiments	-	YES
4481557	26130925	R Kannan	7	Designed the objectives, Rajaretinam|Carried out the experiments, Samuel|Involved in the data interpretation and manuscript preparation	Carried out the experiments, Samuel	Performed the experiments	Investigation	YES
4481557	26130925	R Kannan	7	Designed the objectives, Rajaretinam|Carried out the experiments, Samuel|Involved in the data interpretation and manuscript preparation	Involved in the data interpretation and manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4481557	26130925	Vincent Rajaretinam	7	Involved in the data interpretation and manuscript preparation	Involved in the data interpretation and manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4409401	25799449	IE	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409401	25799449	IE	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409401	25799449	IE	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409401	25799449	JJT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409401	25799449	JJT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4409401	25799449	JJT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4409401	25799449	JJT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4409401	25799449	JJT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409401	25799449	JM	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4409401	25799449	JM	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4696075	26712643	P.M.B.	2	contributed to its revision	contributed to its revision	Wrote the paper	Writing - Review & Editing	YES
4696075	26712643	all other authors	2	contributed to its revision	contributed to its revision	Wrote the paper	Writing - Review & Editing	YES
5465573	28595605	All authors	2	contributed to the discussion of the research and read and approved the final manuscript	contributed to the discussion of the research and read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5465573	28595605	CC	2	performed the experiments and data analysis|wrote the manuscript	performed the experiments and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5465573	28595605	CC	2	performed the experiments and data analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5465573	28595605	DS	2	designed the experiments|supervised the work	designed the experiments	Conceived and designed the experiments	Methodology	YES
5465573	28595605	DS	2	designed the experiments|supervised the work	supervised the work	-	Supervision	YES
5465573	28595605	IM	2	designed the experiments|performed the experiments and data analysis|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5465573	28595605	IM	2	designed the experiments|performed the experiments and data analysis|wrote the manuscript	performed the experiments and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5465573	28595605	IM	2	designed the experiments|performed the experiments and data analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5465573	28595605	IS	2	performed the experiments and data analysis	performed the experiments and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5465573	28595605	MJS	2	wrote the manuscript|supervised the work	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5465573	28595605	MJS	2	wrote the manuscript|supervised the work	supervised the work	-	Supervision	YES
5465573	28595605	RFD	2	designed the experiments|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5465573	28595605	RFD	2	designed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5465573	28595605	SD	2	designed the experiments|wrote the manuscript|supervised the work	designed the experiments	Conceived and designed the experiments	Methodology	YES
5465573	28595605	SD	2	designed the experiments|wrote the manuscript|supervised the work	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5465573	28595605	SD	2	designed the experiments|wrote the manuscript|supervised the work	supervised the work	-	Supervision	YES
1796660	17311105	AV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1796660	17311105	AV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1796660	17311105	AV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1796660	17311105	AV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1796660	17311105	AV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1796660	17311105	CR	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1796660	17311105	CR	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1796660	17311105	CR	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1796660	17311105	JN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1796660	17311105	JN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1796660	17311105	JN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1796660	17311105	JN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1796660	17311105	JN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1796660	17311105	KM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1796660	17311105	KM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1796660	17311105	KM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1796660	17311105	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1796660	17311105	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1796660	17311105	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1796660	17311105	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1796660	17311105	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1796660	17311105	SC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5646179	29081785	GT	2	were edited by the other authors, and upon their approval, was submitted for publication	were edited by the other authors, and upon their approval, was submitted for publication	Wrote the paper	Writing - Review & Editing	YES
5646179	29081785	MRK	2	were edited by the other authors, and upon their approval, was submitted for publication	were edited by the other authors, and upon their approval, was submitted for publication	Wrote the paper	Writing - Review & Editing	YES
5646179	29081785	TMLH	2	were edited by the other authors, and upon their approval, was submitted for publication	were edited by the other authors, and upon their approval, was submitted for publication	Wrote the paper	Writing - Review & Editing	YES
6192899	30334358	All authors	2	reviewed, provided feedback and approved the final manuscript	reviewed, provided feedback and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6192899	30334358	J.T.	2	conceived of the idea for this review|conducted the coding and analysis|prepared the manuscript	conceived of the idea for this review	Conceived and designed the experiments	Conceptualization	YES
6192899	30334358	J.T.	2	conceived of the idea for this review|conducted the coding and analysis|prepared the manuscript	conducted the coding and analysis	Performed the experiments	Investigation	YES
6192899	30334358	J.T.	2	conceived of the idea for this review|conducted the coding and analysis|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
6192899	30334358	M.B.	2	conducted the search	conducted the search	Performed the experiments	Investigation	YES
6192899	30334358	R.S.	2	conceived of the idea for this review	conceived of the idea for this review	Conceived and designed the experiments	Conceptualization	YES
6192899	30334358	S.D.	2	conceived of the idea for this review|conducted the search|extracted the data	conceived of the idea for this review	Conceived and designed the experiments	Conceptualization	YES
6192899	30334358	S.D.	2	conceived of the idea for this review|conducted the search|extracted the data	conducted the search	Performed the experiments	Investigation	YES
6192899	30334358	S.D.	2	conceived of the idea for this review|conducted the search|extracted the data	extracted the data	Performed the experiments	Investigation	YES
6192899	30334358	S.R.	2	conducted the coding and analysis|prepared the manuscript	conducted the coding and analysis	Performed the experiments	Investigation	YES
6192899	30334358	S.R.	2	conducted the coding and analysis|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
6192899	30334358	T.V.	2	extracted the data	extracted the data	Performed the experiments	Investigation	YES
6192899	30334358	Y.Z.	2	extracted the data|prepared the manuscript	extracted the data	Performed the experiments	Investigation	YES
6192899	30334358	Y.Z.	2	extracted the data|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
4707689	26755758	All authors	2	have contributed to the review article	have contributed to the review article	Wrote the paper	Writing - Review & Editing	YES
5649132	29085380	DW	7	Conducted the experiments, analyzed the data, and wrote the manuscript	Conducted the experiments, analyzed the data, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5649132	29085380	HZ	7	Assisted in analyzing the data	Assisted in analyzing the data	Analyzed the data	Formal analysis	YES
5649132	29085380	LW	7	Participated in detecting molecular makers and contributed to the genotyping experiment	Participated in detecting molecular makers and contributed to the genotyping experiment	Performed the experiments	Investigation	YES
5649132	29085380	LY	7	Conducted the experiments, analyzed the data, and wrote the manuscript	Conducted the experiments, analyzed the data, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5649132	29085380	QC	7	Conceived and directed the project and revised the manuscript	Conceived and directed the project and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Supervision|Writing - Review & Editing	YES
5649132	29085380	XC	7	Participated in detecting molecular makers and contributed to the genotyping experiment	Participated in detecting molecular makers and contributed to the genotyping experiment	Performed the experiments	Investigation	YES
5649132	29085380	YC	7	Conceived and directed the project and revised the manuscript	Conceived and directed the project and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Supervision|Writing - Review & Editing	YES
5649132	29085380	YX	7	Identified the resistant parental line and made the cross	Identified the resistant parental line and made the cross	Performed the experiments	Investigation	YES
4558423	26366419	J. Niklinski	2	coordinated molecular biology experiments and analysed the data	coordinated molecular biology experiments and analysed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Project administration	YES
4558423	26366419	J. Szamatowicz	2	helped in the collection of samples and molecular biology interpretation and analysis of data	helped in the collection of samples and molecular biology interpretation and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4558423	26366419	P. Laudanski	2	had an idea that designated the study, participated in the laboratory work, analysed the data, and wrote the paper	had an idea that designated the study, participated in the laboratory work, analysed the data, and wrote the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4558423	26366419	PCR	2	array experiments|array experiments and writing the paper|array experiments	array experiments	Performed the experiments	Investigation	YES
4558423	26366419	PCR	2	array experiments|array experiments and writing the paper|array experiments	array experiments and writing the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4558423	26366419	PCR	2	array experiments|array experiments and writing the paper|array experiments	array experiments	Performed the experiments	Investigation	YES
4409402	25909185	ABD	PLoS5	Analyzed the data|Wrote the paper|Modelling	Analyzed the data	Analyzed the data	Formal analysis	YES
4409402	25909185	ABD	PLoS5	Analyzed the data|Wrote the paper|Modelling	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409402	25909185	ABD	PLoS5	Analyzed the data|Wrote the paper|Modelling	Modelling	Performed the experiments	Methodology	YES
4409402	25909185	JMR	PLoS5	Analyzed the data|Wrote the paper|Modelling	Analyzed the data	Analyzed the data	Formal analysis	YES
4409402	25909185	JMR	PLoS5	Analyzed the data|Wrote the paper|Modelling	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4409402	25909185	JMR	PLoS5	Analyzed the data|Wrote the paper|Modelling	Modelling	Performed the experiments	Methodology	YES
4481559	26130921	Geeta Shroff	7	Drafted the manuscript, carried out the experiments, conceived of the study, and participated in its design and coordination and helped to draft the manuscript, J	Drafted the manuscript, carried out the experiments, conceived of the study, and participated in its design and coordination and helped to draft the manuscript, J	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Project administration|Writing - Original Draft	YES
4481559	26130921	K Barthakur	7	participated in the design of the study and performed the statistical analysis, Geeta Shroff and J|Read and approved the final manuscript	participated in the design of the study and performed the statistical analysis, Geeta Shroff and J	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
4481559	26130921	K Barthakur	7	participated in the design of the study and performed the statistical analysis, Geeta Shroff and J|Read and approved the final manuscript	Read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
1796944	17327909	BC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1796944	17327909	BC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1796944	17327909	BC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1796944	17327909	BC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1796944	17327909	RG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1796944	17327909	RG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1796944	17327909	RG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1796944	17327909	RG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1796944	17327909	WM	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1796944	17327909	WM	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4707690	26755760	all authors	2	were involved in the conception and design of the experiments, drafting and revising the manuscript, and final approval	were involved in the conception and design of the experiments, drafting and revising the manuscript, and final approval	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5466789	28599643	DLA	PLoS52	analyzed the results	analyzed the results	Analyzed the data	Formal analysis	YES
5466789	28599643	FBC	PLoS52	analyzed the results	analyzed the results	Analyzed the data	Formal analysis	YES
5466789	28599643	MCB	PLoS52	analyzed the results|wrote the paper	analyzed the results	Analyzed the data	Formal analysis	YES
5466789	28599643	MCB	PLoS52	analyzed the results|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5466789	28599643	SV	PLoS52	performed most of the experiments|analyzed the results|wrote the paper	performed most of the experiments	Performed the experiments	Investigation	YES
5466789	28599643	SV	PLoS52	performed most of the experiments|analyzed the results|wrote the paper	analyzed the results	Analyzed the data	Formal analysis	YES
5466789	28599643	SV	PLoS52	performed most of the experiments|analyzed the results|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6193312	30334600	All authors	2	have contributed substantially to the conception and design of the manuscript or acquisition, analysis or interpretation of the data for this work|contributed to the writing of the manuscript	have contributed substantially to the conception and design of the manuscript or acquisition, analysis or interpretation of the data for this work	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
6193312	30334600	All authors	2	have contributed substantially to the conception and design of the manuscript or acquisition, analysis or interpretation of the data for this work|contributed to the writing of the manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
6193312	30334600	Black Caucus Vice	2	provided socio-cultural expertise for the study	provided socio-cultural expertise for the study	-	-	NO
6193312	30334600	DPW	2	provided scientific leadership in the conceptualization, development and implementation of the study	provided scientific leadership in the conceptualization, development and implementation of the study	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Supervision	YES
6193312	30334600	Each author	2	has participated in the drafting or revision of the content	has participated in the drafting or revision of the content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6193312	30334600	GB	2	provided statistical analysis for the study	provided statistical analysis for the study	Analyzed the data	Formal analysis	YES
6193312	30334600	HPTN	2	provided socio-cultural expertise for the study	provided socio-cultural expertise for the study	-	-	NO
6193312	30334600	JPL	2	provided scientific leadership in all phases of community engagement for the study	provided scientific leadership in all phases of community engagement for the study	-	Supervision	YES
6193312	30334600	KHM	2	provided scientific leadership in the conceptualization, development and implementation of the study|served as a protocol team member and provided scientific-, medical- and health-related expertise for the study	provided scientific leadership in the conceptualization, development and implementation of the study	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Supervision	YES
6193312	30334600	KHM	2	provided scientific leadership in the conceptualization, development and implementation of the study|served as a protocol team member and provided scientific-, medical- and health-related expertise for the study	served as a protocol team member and provided scientific-, medical- and health-related expertise for the study	Conceived and designed the experiments	Methodology	YES
6193312	30334600	LEN	2	was the lead implementation scientist for the study|provided scientific leadership in the conceptualization, development and implementation of the study	was the lead implementation scientist for the study	Performed the experiments	Investigation	YES
6193312	30334600	LEN	2	was the lead implementation scientist for the study|provided scientific leadership in the conceptualization, development and implementation of the study	provided scientific leadership in the conceptualization, development and implementation of the study	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Supervision	YES
6193312	30334600	LHW	2	were the site investigators for the study in their respective cities|provided scientific leadership in the conceptualization, development and implementation of the study	were the site investigators for the study in their respective cities	-	-	NO
6193312	30334600	LHW	2	were the site investigators for the study in their respective cities|provided scientific leadership in the conceptualization, development and implementation of the study	provided scientific leadership in the conceptualization, development and implementation of the study	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Supervision	YES
6193312	30334600	LME	2	supervised data management for the study	supervised data management for the study	Analyzed the data	Data curation|Project administration|Supervision	YES
6193312	30334600	LW	2	provided scientific leadership in the conceptualization, development and implementation of the study	provided scientific leadership in the conceptualization, development and implementation of the study	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Supervision	YES
6193312	30334600	MM	2	were the site investigators for the study in their respective cities|provided scientific leadership in the conceptualization, development and implementation of the study	were the site investigators for the study in their respective cities	-	-	NO
6193312	30334600	MM	2	were the site investigators for the study in their respective cities|provided scientific leadership in the conceptualization, development and implementation of the study	provided scientific leadership in the conceptualization, development and implementation of the study	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Supervision	YES
6193312	30334600	PI	2	for her respective site	for her respective site	-	-	NO
6193312	30334600	SDF	2	was the co-chair of the study|provided scientific leadership in the conceptualization, development and implementation of the study	was the co-chair of the study	-	-	NO
6193312	30334600	SDF	2	was the co-chair of the study|provided scientific leadership in the conceptualization, development and implementation of the study	provided scientific leadership in the conceptualization, development and implementation of the study	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Supervision	YES
6193312	30334600	SS	2	were the site investigators for the study in their respective cities|provided scientific leadership in the conceptualization, development and implementation of the study	were the site investigators for the study in their respective cities	-	-	NO
6193312	30334600	SS	2	were the site investigators for the study in their respective cities|provided scientific leadership in the conceptualization, development and implementation of the study	provided scientific leadership in the conceptualization, development and implementation of the study	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Supervision	YES
6193312	30334600	YQC	2	provided statistical analysis for the study	provided statistical analysis for the study	Analyzed the data	Formal analysis	YES
4410915	25915064	GN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4410915	25915064	GN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4410915	25915064	GN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4410915	25915064	GN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4410915	25915064	HL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4410915	25915064	JQ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4410915	25915064	JQ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4410915	25915064	JQ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4410915	25915064	JZ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4410915	25915064	LZ	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4410915	25915064	LZ	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4410915	25915064	MH	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4410915	25915064	YC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4410915	25915064	YZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4410915	25915064	ZC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4410915	25915064	ZF	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5649140	29085377	All authors	2	read the ms and provided their consent|read and approved the final manuscript	read the ms and provided their consent	-	-	NO
5649140	29085377	All authors	2	read the ms and provided their consent|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4484368	26130913	K S Rao	7	Conceived the idea, designed the stimuli, assisted in writing the paper	Conceived the idea, designed the stimuli, assisted in writing the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4484368	26130913	Kuppuraj Sengottuvel	7	Conceived the idea, collected data, analyzed the data, wrote the paper, Prema	Conceived the idea, collected data, analyzed the data, wrote the paper, Prema	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
5467262	28606096	ARB	2	executed pipelines, analyzed data, and drafted the manuscript|designed figures|designed experiments	executed pipelines, analyzed data, and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5467262	28606096	ARB	2	executed pipelines, analyzed data, and drafted the manuscript|designed figures|designed experiments	designed figures	Conceived and designed the experiments	Visualization	YES
5467262	28606096	ARB	2	executed pipelines, analyzed data, and drafted the manuscript|designed figures|designed experiments	designed experiments	Conceived and designed the experiments	Methodology	YES
5467262	28606096	HC	2	designed experiments|helped write the manuscript	designed experiments	Conceived and designed the experiments	Methodology	YES
5467262	28606096	HC	2	designed experiments|helped write the manuscript	helped write the manuscript	Wrote the paper	Writing - Original Draft	YES
5467262	28606096	KAS	2	helped assemble pipelines and assisted with statistical analysis|designed figures|designed experiments	helped assemble pipelines and assisted with statistical analysis	Analyzed the data	Formal analysis	YES
5467262	28606096	KAS	2	helped assemble pipelines and assisted with statistical analysis|designed figures|designed experiments	designed figures	Conceived and designed the experiments	Visualization	YES
5467262	28606096	KAS	2	helped assemble pipelines and assisted with statistical analysis|designed figures|designed experiments	designed experiments	Conceived and designed the experiments	Methodology	YES
5467262	28606096	KB	2	designed experiments	designed experiments	Conceived and designed the experiments	Methodology	YES
5467262	28606096	NJS	2	designed and supervised the research|helped write the manuscript	designed and supervised the research	Conceived and designed the experiments	Methodology|Supervision	YES
5467262	28606096	NJS	2	designed and supervised the research|helped write the manuscript	helped write the manuscript	Wrote the paper	Writing - Original Draft	YES
5467262	28606096	OH	2	designed experiments|helped write the manuscript	designed experiments	Conceived and designed the experiments	Methodology	YES
5467262	28606096	OH	2	designed experiments|helped write the manuscript	helped write the manuscript	Wrote the paper	Writing - Original Draft	YES
5467262	28606096	RSL	2	designed figures|designed experiments	designed figures	Conceived and designed the experiments	Visualization	YES
5467262	28606096	RSL	2	designed figures|designed experiments	designed experiments	Conceived and designed the experiments	Methodology	YES
5467262	28606096	TI	2	set up high performance computing infrastructure	set up high performance computing infrastructure	Performed the experiments	Formal analysis|Investigation|Methodology	YES
1796945	17327910	BH	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1796945	17327910	DS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1796945	17327910	DS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1796945	17327910	ES	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1796945	17327910	ES	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1796945	17327910	ES	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1796945	17327910	FT	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1796945	17327910	FT	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1796945	17327910	MD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1796945	17327910	MD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1796945	17327910	MD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1796945	17327910	MD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1796945	17327910	ML	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1796945	17327910	ML	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5650606	29085384	All authors	2	listed have made a substantial, direct and intellectual contribution to the work, and approved it for publication	listed have made a substantial, direct and intellectual contribution to the work, and approved it for publication	-	-	NO
6193313	30334601	All authors	2	contributed to the writing of the manuscript and reviewed and approved the final version	contributed to the writing of the manuscript and reviewed and approved the final version	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6193313	30334601	CH	2	contributed to conception and design of the study and interpretation of the data|contributed to critical revisions	contributed to conception and design of the study and interpretation of the data	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Methodology|Resources	YES
6193313	30334601	CH	2	contributed to conception and design of the study and interpretation of the data|contributed to critical revisions	contributed to critical revisions	Wrote the paper	Writing - Review & Editing	YES
6193313	30334601	KM	2	contributed to conception and design of the study and interpretation of the data|contributed to data collection and analysis	contributed to conception and design of the study and interpretation of the data	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Methodology|Resources	YES
6193313	30334601	KM	2	contributed to conception and design of the study and interpretation of the data|contributed to data collection and analysis	contributed to data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6193313	30334601	MF	2	contributed to conception and design of the study and interpretation of the data|contributed to critical revisions	contributed to conception and design of the study and interpretation of the data	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Methodology|Resources	YES
6193313	30334601	MF	2	contributed to conception and design of the study and interpretation of the data|contributed to critical revisions	contributed to critical revisions	Wrote the paper	Writing - Review & Editing	YES
6193313	30334601	NE	2	contributed to conception and design of the study and interpretation of the data|contributed to data collection and analysis|contributed to critical revisions	contributed to conception and design of the study and interpretation of the data	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Methodology|Resources	YES
6193313	30334601	NE	2	contributed to conception and design of the study and interpretation of the data|contributed to data collection and analysis|contributed to critical revisions	contributed to data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6193313	30334601	NE	2	contributed to conception and design of the study and interpretation of the data|contributed to data collection and analysis|contributed to critical revisions	contributed to critical revisions	Wrote the paper	Writing - Review & Editing	YES
4733919	26809572	A.A.	2	contributed the analysis of mutual information and application of coding	contributed the analysis of mutual information and application of coding	-	-	NO
4733919	26809572	All authors	2	made significant contributions to this paper, its structure and various revisions|gave final approval for publication	made significant contributions to this paper, its structure and various revisions	Wrote the paper	Writing - Review & Editing	YES
4733919	26809572	All authors	2	made significant contributions to this paper, its structure and various revisions|gave final approval for publication	gave final approval for publication	-	-	NO
4733919	26809572	D.L.	2	undertook the analysis of channel models and estimates of channel capacity	undertook the analysis of channel models and estimates of channel capacity	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
4733919	26809572	G.L.	2	had a very substantial part	had a very substantial part	-	-	NO
4733919	26809572	N.A.S.	2	undertook the analysis of channel models and estimates of channel capacity	undertook the analysis of channel models and estimates of channel capacity	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
4733919	26809572	P.B.	2	proposed the structure of the paper, and contributed to the ideas, analysis and discussion of the results	proposed the structure of the paper, and contributed to the ideas, analysis and discussion of the results	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
4733919	26809572	R.I.K.	2	contributed to numerous discussions of the ideas described in this paper and its revision	contributed to numerous discussions of the ideas described in this paper and its revision	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
4733919	26809572	T.X.	2	undertook the analysis of channel models and estimates of channel capacity	undertook the analysis of channel models and estimates of channel capacity	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
4410917	25915945	EM	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4410917	25915945	EM	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4410917	25915945	GH	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4410917	25915945	MC	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4410917	25915945	MC	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4410917	25915945	MGDB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4410917	25915945	MGDB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4410917	25915945	MGDB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4410917	25915945	MGDB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4410917	25915945	MJB	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4410917	25915945	MM	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4410917	25915945	MM	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4410917	25915945	MU	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4410917	25915945	RB	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4410917	25915945	SC	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4410917	25915945	VO	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4410917	25915945	WS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5650612	29085381	All authors	2	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5650612	29085381	CY	2	established the root cultures	established the root cultures	Performed the experiments	Investigation	YES
5650612	29085381	FQ	2	participated in the enzymatic assays	participated in the enzymatic assays	Performed the experiments	Investigation	YES
5650612	29085381	HZ	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5650612	29085381	JZ	2	conducted the experiments, including the planting, gene cloning, protein recombination, enzymatic assays, molecular analysis, and alkaloid detection	conducted the experiments, including the planting, gene cloning, protein recombination, enzymatic assays, molecular analysis, and alkaloid detection	Performed the experiments	Investigation	YES
5650612	29085381	KZ	2	conducted the experiments, including the planting, gene cloning, protein recombination, enzymatic assays, molecular analysis, and alkaloid detection	conducted the experiments, including the planting, gene cloning, protein recombination, enzymatic assays, molecular analysis, and alkaloid detection	Performed the experiments	Investigation	YES
5650612	29085381	MC	2	analyzed the gc-ms data	analyzed the gc-ms data	Analyzed the data	Formal analysis	YES
5650612	29085381	TZ	2	conducted the experiments, including the planting, gene cloning, protein recombination, enzymatic assays, molecular analysis, and alkaloid detection	conducted the experiments, including the planting, gene cloning, protein recombination, enzymatic assays, molecular analysis, and alkaloid detection	Performed the experiments	Investigation	YES
5650612	29085381	XQL	2	participated in the enzymatic assays	participated in the enzymatic assays	Performed the experiments	Investigation	YES
5650612	29085381	XZL	2	conceived the experiments and wrote the manuscript	conceived the experiments and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5650612	29085381	ZL	2	conceived the experiments and wrote the manuscript	conceived the experiments and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
1797199	17311106	AJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1797199	17311106	AJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1797199	17311106	AJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1797199	17311106	AJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1797199	17311106	HS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1797199	17311106	HS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1797199	17311106	HS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1797199	17311106	HS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4558430	26366411	Chia-Chou Wu	2	contributed equally to this work	contributed equally to this work	-	-	NO
4558430	26366411	Yung-Hao Wong	2	contributed equally to this work	contributed equally to this work	-	-	NO
5467263	28606056	AY	2	designed the experiment|analyzed the data and wrote the manuscript	designed the experiment	Conceived and designed the experiments	Methodology	YES
5467263	28606056	AY	2	designed the experiment|analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5467263	28606056	HC	2	designed the experiment|did the experiment|analyzed the data and wrote the manuscript	designed the experiment	Conceived and designed the experiments	Methodology	YES
5467263	28606056	HC	2	designed the experiment|did the experiment|analyzed the data and wrote the manuscript	did the experiment	Performed the experiments	Investigation	YES
5467263	28606056	HC	2	designed the experiment|did the experiment|analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5467263	28606056	SB	2	did the experiment	did the experiment	Performed the experiments	Investigation	YES
5467263	28606056	YL	2	did the experiment	did the experiment	Performed the experiments	Investigation	YES
5467263	28606056	ZX	2	did the experiment	did the experiment	Performed the experiments	Investigation	YES
6193314	30334608	J.D.A.	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6193314	30334608	K.M.M.	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4627194	26525840	Khushboo Srivastava	7	Repeated transfection experiments and isolated rna and prepared cdna	Repeated transfection experiments and isolated rna and prepared cdna	Performed the experiments	Investigation	YES
4627194	26525840	Rajnikant Mishra	7	Planned experiments and mentored the progress of experiments, from initiation to completion of manuscript	Planned experiments and mentored the progress of experiments, from initiation to completion of manuscript	Conceived and designed the experiments	Conceptualization|Supervision	YES
4627194	26525840	Sachin Shukla	7	Initiated the work and did qpcr experiments following transfection	Initiated the work and did qpcr experiments following transfection	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
4627194	26525840	Shashank Kumar Maurya	7	Equally contributed for rt pcr based experiments, compiled data and wrote their part of explanations	Equally contributed for rt pcr based experiments, compiled data and wrote their part of explanations	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Data curation|Investigation|Resources|Writing - Original Draft	YES
4627194	26525840	Shuman Mishra	7	Equally contributed for rt pcr based experiments, compiled data and wrote their part of explanations	Equally contributed for rt pcr based experiments, compiled data and wrote their part of explanations	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Data curation|Investigation|Resources|Writing - Original Draft	YES
4410918	25915524	ED	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4410918	25915524	ED	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4410918	25915524	ED	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4410918	25915524	ED	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4410918	25915524	LB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4410918	25915524	LB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4410918	25915524	LB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4410918	25915524	LB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4410918	25915524	LB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4410918	25915524	NFB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4410918	25915524	NFB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4410918	25915524	NFB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4410918	25915524	NFB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4410918	25915524	OD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4410918	25915524	OD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4410918	25915524	OD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4410918	25915524	OD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4410918	25915524	PB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4410918	25915524	PB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4410918	25915524	PB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4410918	25915524	PB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4410918	25915524	PN	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4410918	25915524	PN	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4410918	25915524	TR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4410918	25915524	TR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4410918	25915524	TR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4410918	25915524	TR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1797416	17311107	EP	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1797416	17311107	EP	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1797416	17311107	NS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1797416	17311107	NS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1797416	17311107	NS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1797416	17311107	OL	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1797416	17311107	OL	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1797416	17311107	TS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1797416	17311107	TS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1797416	17311107	VR	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1797416	17311107	YM	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1797416	17311107	YM	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1797416	17311107	YM	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1797416	17311107	YM	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1797416	17311107	YM	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1797416	17311107	YM	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1797416	17311107	YM	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1797416	17311107	YM	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5470263	28610613	CS	2	provided materials and data	provided materials and data	Contributed reagents/materials/analysis tools	Resources	YES
5470263	28610613	FB	2	provided materials and data	provided materials and data	Contributed reagents/materials/analysis tools	Resources	YES
5470263	28610613	GY	2	provided materials and data	provided materials and data	Contributed reagents/materials/analysis tools	Resources	YES
5470263	28610613	JG	2	performed molecular lab work|the other authors	performed molecular lab work	Performed the experiments	Investigation	YES
5470263	28610613	JG	2	performed molecular lab work|the other authors	the other authors	-	-	NO
5470263	28610613	KDM	2	provided materials and data	provided materials and data	Contributed reagents/materials/analysis tools	Resources	YES
5470263	28610613	LF	2	conceived the study|the other authors	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5470263	28610613	LF	2	conceived the study|the other authors	the other authors	-	-	NO
5470263	28610613	MP	2	performed molecular lab work	performed molecular lab work	Performed the experiments	Investigation	YES
5470263	28610613	MS	2	provided materials and data	provided materials and data	Contributed reagents/materials/analysis tools	Resources	YES
5470263	28610613	RB	2	conceived the study|performed molecular lab work	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5470263	28610613	RB	2	conceived the study|performed molecular lab work	performed molecular lab work	Performed the experiments	Investigation	YES
5650620	29085379	BS	2	co-planned the experiments, co-analyzed the data and co-wrote the paper	co-planned the experiments, co-analyzed the data and co-wrote the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
5650620	29085379	RF	2	co-planned the experiments, co-analyzed the data and co-wrote the paper	co-planned the experiments, co-analyzed the data and co-wrote the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
6193315	30334609	CR	2	conceptualized the commentary	conceptualized the commentary	Conceived and designed the experiments	Conceptualization	YES
6193315	30334609	ER	2	conceptualized the commentary|provided content on implications for research	conceptualized the commentary	Conceived and designed the experiments	Conceptualization	YES
6193315	30334609	ER	2	conceptualized the commentary|provided content on implications for research	provided content on implications for research	-	-	NO
6193315	30334609	HIV	2	prevention programming	prevention programming	Contributed reagents/materials/analysis tools	Software	YES
6193315	30334609	MP	2	conceptualized the commentary|provided content on implications for research|drafted the manuscript, and all authors contributed to revisions	conceptualized the commentary	Conceived and designed the experiments	Conceptualization	YES
6193315	30334609	MP	2	conceptualized the commentary|provided content on implications for research|drafted the manuscript, and all authors contributed to revisions	provided content on implications for research	-	-	NO
6193315	30334609	MP	2	conceptualized the commentary|provided content on implications for research|drafted the manuscript, and all authors contributed to revisions	drafted the manuscript, and all authors contributed to revisions	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6193315	30334609	SS	2	conceptualized the commentary	conceptualized the commentary	Conceived and designed the experiments	Conceptualization	YES
4410919	25915658	CHM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4410919	25915658	CHM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4410919	25915658	CHM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4410919	25915658	FCS	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4410919	25915658	SCW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4410919	25915658	SCW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4410919	25915658	SCW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4410919	25915658	WTLC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4733921	26809573	A.W.M.	2	jointly conceived this work, collecting and analysing the trend data and arriving at the architectural outline|helped prepare the manuscript	jointly conceived this work, collecting and analysing the trend data and arriving at the architectural outline	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation	YES
4733921	26809573	A.W.M.	2	jointly conceived this work, collecting and analysing the trend data and arriving at the architectural outline|helped prepare the manuscript	helped prepare the manuscript	Wrote the paper	Writing - Original Draft	YES
4733921	26809573	All authors	2	gave final approval for publication	gave final approval for publication	-	-	NO
4733921	26809573	J.A.C.	2	inspired the original direction, provided motivating use-cases and made significant contributions to the manuscript	inspired the original direction, provided motivating use-cases and made significant contributions to the manuscript	-	-	NO
4733921	26809573	N.Z.	2	jointly conceived this work, collecting and analysing the trend data and arriving at the architectural outline	jointly conceived this work, collecting and analysing the trend data and arriving at the architectural outline	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation	YES
1797488	17327916	AL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1797488	17327916	AL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1797488	17327916	AL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1797488	17327916	AL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1797488	17327916	CL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1797488	17327916	CL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1797488	17327916	DN	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1797488	17327916	DN	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1797488	17327916	EA	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Prepared figures	Performed the experiments	Performed the experiments	Investigation	YES
1797488	17327916	EA	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Prepared figures	Analyzed the data	Analyzed the data	Formal analysis	YES
1797488	17327916	EA	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Prepared figures	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1797488	17327916	EA	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Prepared figures	Prepared figures	-	Visualization	YES
1797488	17327916	EF	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1797488	17327916	EF	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1797488	17327916	JM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1797488	17327916	JM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1797488	17327916	JM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1797488	17327916	JM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1797488	17327916	LD	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1797488	17327916	LD	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1797488	17327916	LM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1797488	17327916	LM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1797488	17327916	MM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1797488	17327916	MM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1797488	17327916	PF	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1797488	17327916	RG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1797488	17327916	RG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1797488	17327916	RG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1797488	17327916	RG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1797488	17327916	RG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1797488	17327916	SL	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5470264	28610618	DG	2	generated samples for the time series|wrote the manuscript	generated samples for the time series	Performed the experiments	Investigation	YES
5470264	28610618	DG	2	generated samples for the time series|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5470264	28610618	DS	2	generated samples for the time series	generated samples for the time series	Performed the experiments	Investigation	YES
5470264	28610618	ED	2	performed data analysis|wrote the manuscript	performed data analysis	Analyzed the data	Formal analysis	YES
5470264	28610618	ED	2	performed data analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5470264	28610618	FANTOM	2	consortium performed heliscopecage and data processing	consortium performed heliscopecage and data processing	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5470264	28610618	PZ	2	generated samples for the time series|performed data analysis|performed biological validation experiments|wrote the manuscript	generated samples for the time series	Performed the experiments	Investigation	YES
5470264	28610618	PZ	2	generated samples for the time series|performed data analysis|performed biological validation experiments|wrote the manuscript	performed data analysis	Analyzed the data	Formal analysis	YES
5470264	28610618	PZ	2	generated samples for the time series|performed data analysis|performed biological validation experiments|wrote the manuscript	performed biological validation experiments	Performed the experiments	Investigation|Validation	YES
5470264	28610618	PZ	2	generated samples for the time series|performed data analysis|performed biological validation experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5470264	28610618	TH	2	generated samples for the time series	generated samples for the time series	Performed the experiments	Investigation	YES
5470264	28610618	WH	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5650622	29085378	AR	2	gave final approval for publication of manuscript	gave final approval for publication of manuscript	-	-	NO
5650622	29085378	AS	2	supervised the write up the initial draft of manuscript under the	supervised the write up the initial draft of manuscript under the	Wrote the paper	Supervision|Writing - Original Draft	YES
5650622	29085378	AY	2	edited the manuscript for minor corrections	edited the manuscript for minor corrections	Wrote the paper	Writing - Review & Editing	YES
5650622	29085378	IS	2	write up the initial draft of manuscript under the	write up the initial draft of manuscript under the	Wrote the paper	Writing - Original Draft	YES
5650622	29085378	QA	2	make final version of the manuscript after important changes	make final version of the manuscript after important changes	-	-	NO
5650622	29085378	TH	2	gave final approval for publication of manuscript	gave final approval for publication of manuscript	-	-	NO
5650622	29085378	The author	2	write up the initial draft of manuscript under the	write up the initial draft of manuscript under the	Wrote the paper	Writing - Original Draft	YES
4733922	26809575	A.D.E.	2	provided final approval of the version to be published	provided final approval of the version to be published	-	-	NO
4733922	26809575	N.M.S.	2	made substantial contributions to the analysis of the population and capacity growth data featuring in figures 1 and 2 and revised this article critically for important intellectual content	made substantial contributions to the analysis of the population and capacity growth data featuring in figures 1 and 2 and revised this article critically for important intellectual content	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Visualization|Writing - Review & Editing	YES
4410920	25915417	PR	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4410920	25915417	PR	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4410920	25915417	PR	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4410920	25915417	SM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4410920	25915417	SM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4410920	25915417	SM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6193316	30334610	All co-authors	2	reviewed and gave input on the final draft, and cleared it for submission	reviewed and gave input on the final draft, and cleared it for submission	Wrote the paper	Writing - Original Draft	YES
6193316	30334610	DB	2	drafted the first draft of the manuscript, developed the conceptual model with input from co-authors and managed revisions|discussed key ideas and concepts forming the basis of this commentary	drafted the first draft of the manuscript, developed the conceptual model with input from co-authors and managed revisions	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
6193316	30334610	DB	2	drafted the first draft of the manuscript, developed the conceptual model with input from co-authors and managed revisions|discussed key ideas and concepts forming the basis of this commentary	discussed key ideas and concepts forming the basis of this commentary	Conceived and designed the experiments	Conceptualization	YES
6193316	30334610	FS	2	reviewed and substantively revised early drafts	reviewed and substantively revised early drafts	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6193316	30334610	MM	2	discussed key ideas and concepts forming the basis of this commentary	discussed key ideas and concepts forming the basis of this commentary	Conceived and designed the experiments	Conceptualization	YES
6193316	30334610	NM	2	discussed key ideas and concepts forming the basis of this commentary	discussed key ideas and concepts forming the basis of this commentary	Conceived and designed the experiments	Conceptualization	YES
6193316	30334610	SDM	2	discussed key ideas and concepts forming the basis of this commentary|reviewed and substantively revised early drafts	discussed key ideas and concepts forming the basis of this commentary	Conceived and designed the experiments	Conceptualization	YES
6193316	30334610	SDM	2	discussed key ideas and concepts forming the basis of this commentary|reviewed and substantively revised early drafts	reviewed and substantively revised early drafts	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6193316	30334610	SP	2	discussed key ideas and concepts forming the basis of this commentary	discussed key ideas and concepts forming the basis of this commentary	Conceived and designed the experiments	Conceptualization	YES
6193316	30334610	TE	2	discussed key ideas and concepts forming the basis of this commentary	discussed key ideas and concepts forming the basis of this commentary	Conceived and designed the experiments	Conceptualization	YES
4558435	26366416	Ya Yang	2	contributed equally to this work	contributed equally to this work	-	-	NO
4558435	26366416	Yanxia Sui	2	contributed equally to this work	contributed equally to this work	-	-	NO
4627200	26526209	Akshay Anand	7	Designed, supervised and provided resources for the study	Designed, supervised and provided resources for the study	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Methodology|Resources|Supervision	YES
4627200	26526209	FFA	7	Designed, supervised and provided resources for the study	Designed, supervised and provided resources for the study	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Methodology|Resources|Supervision	YES
4627200	26526209	Gillipsie Minhas	7	Performed the surgery	Performed the surgery	Performed the experiments	Investigation	YES
4627200	26526209	Munehisa Shimamura	7	Provided training	Provided training	-	-	NO
4627200	26526209	Reema Bansal	7	Supervised the	Supervised the	-	Supervision	YES
4627200	26526209	Ryuichi Morishita	7	Provided training	Provided training	-	-	NO
1797610	17330139	KR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1797610	17330139	KR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1797610	17330139	KR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1797610	17330139	KR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1797610	17330139	KR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1797610	17330139	TC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1797610	17330139	TC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1797610	17330139	TC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1797610	17330139	TC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1797610	17330139	TC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5650624	29085382	FB	PLoS5	Performed the experiment|Wrote the paper	Performed the experiment	Performed the experiments	Investigation	YES
5650624	29085382	FB	PLoS5	Performed the experiment|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5650624	29085382	GC	PLoS5	Conceived and designed the experiment|Analyzed data	Conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5650624	29085382	GC	PLoS5	Conceived and designed the experiment|Analyzed data	Analyzed data	Analyzed the data	Formal analysis	YES
5650624	29085382	JS	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5650624	29085382	LS	PLoS5	Performed the experiment|Analyzed data	Performed the experiment	Performed the experiments	Investigation	YES
5650624	29085382	LS	PLoS5	Performed the experiment|Analyzed data	Analyzed data	Analyzed the data	Formal analysis	YES
5650624	29085382	LZ	PLoS5	Conceived and designed the experiment|Performed the experiment|Analyzed data|Wrote the paper	Conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5650624	29085382	LZ	PLoS5	Conceived and designed the experiment|Performed the experiment|Analyzed data|Wrote the paper	Performed the experiment	Performed the experiments	Investigation	YES
5650624	29085382	LZ	PLoS5	Conceived and designed the experiment|Performed the experiment|Analyzed data|Wrote the paper	Analyzed data	Analyzed the data	Formal analysis	YES
5650624	29085382	LZ	PLoS5	Conceived and designed the experiment|Performed the experiment|Analyzed data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5650624	29085382	SW	PLoS5	Conceived and designed the experiment|Analyzed data|Wrote the paper	Conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5650624	29085382	SW	PLoS5	Conceived and designed the experiment|Analyzed data|Wrote the paper	Analyzed data	Analyzed the data	Formal analysis	YES
5650624	29085382	SW	PLoS5	Conceived and designed the experiment|Analyzed data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5650624	29085382	XL	PLoS5	Analyzed data|Wrote the paper	Analyzed data	Analyzed the data	Formal analysis	YES
5650624	29085382	XL	PLoS5	Analyzed data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5650624	29085382	ZP	PLoS5	Conceived and designed the experiment|Performed the experiment	Conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5650624	29085382	ZP	PLoS5	Conceived and designed the experiment|Performed the experiment	Performed the experiment	Performed the experiments	Investigation	YES
6193317	30334604	AW	2	reviewed ethics guidelines and drafted the manuscript	reviewed ethics guidelines and drafted the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6193317	30334604	CS	2	designed the paper, reviewed ethics guidelines and drafted the manuscript	designed the paper, reviewed ethics guidelines and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6193317	30334604	JS	2	helped interpret the review and revised the manuscript for important content	helped interpret the review and revised the manuscript for important content	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
6193317	30334604	PN	2	helped interpret the review and revised the manuscript for important content	helped interpret the review and revised the manuscript for important content	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5471737	28615053	DML	PLoS52	conducted the molecular experiments	conducted the molecular experiments	Performed the experiments	Investigation	YES
5471737	28615053	DYL	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5471737	28615053	HKZ	PLoS52	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5471737	28615053	LJQ	PLoS52	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5471737	28615053	WBL	PLoS52	designed and supervised the research|drafted the manuscript	designed and supervised the research	Conceived and designed the experiments	Methodology|Supervision	YES
5471737	28615053	WBL	PLoS52	designed and supervised the research|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5471737	28615053	WLT	PLoS52	conducted the molecular experiments	conducted the molecular experiments	Performed the experiments	Investigation	YES
5471737	28615053	XZ	PLoS52	analyzed the data|drafted the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5471737	28615053	XZ	PLoS52	analyzed the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5471737	28615053	YHL	PLoS52	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5471737	28615053	YPH	PLoS52	analyzed the data|drafted the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5471737	28615053	YPH	PLoS52	analyzed the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4410921	25915755	CC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Contributed to the study subject recruitment and sample collection	Analyzed the data	Analyzed the data	Formal analysis	YES
4410921	25915755	CC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Contributed to the study subject recruitment and sample collection	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4410921	25915755	CC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Contributed to the study subject recruitment and sample collection	Contributed to the study subject recruitment and sample collection	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4410921	25915755	CL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Contributed to the study subject recruitment and sample collection	Analyzed the data	Analyzed the data	Formal analysis	YES
4410921	25915755	CL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Contributed to the study subject recruitment and sample collection	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4410921	25915755	CL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Contributed to the study subject recruitment and sample collection	Contributed to the study subject recruitment and sample collection	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4410921	25915755	HW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4410921	25915755	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4410921	25915755	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4410921	25915755	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4410921	25915755	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4410921	25915755	JP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4410921	25915755	KC	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4410921	25915755	KC	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4410921	25915755	KN	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4410921	25915755	LL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4410921	25915755	LL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4410921	25915755	LL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4410921	25915755	LL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4410921	25915755	MC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Contributed to the study subject recruitment and sample collection	Analyzed the data	Analyzed the data	Formal analysis	YES
4410921	25915755	MC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Contributed to the study subject recruitment and sample collection	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4410921	25915755	MC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Contributed to the study subject recruitment and sample collection	Contributed to the study subject recruitment and sample collection	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4410921	25915755	ML	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Contributed to the study subject recruitment and sample collection	Analyzed the data	Analyzed the data	Formal analysis	YES
4410921	25915755	ML	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Contributed to the study subject recruitment and sample collection	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4410921	25915755	ML	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Contributed to the study subject recruitment and sample collection	Contributed to the study subject recruitment and sample collection	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4410921	25915755	WY	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4410921	25915755	XT	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4410921	25915755	ZC	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4410921	25915755	ZC	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4410921	25915755	ZT	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4627201	26526368	A Forero	7	Participated in study design, statistical analysis and interpretation of data, revising the final paper, Claudia T-Gutierrez: Participated in design, study supervision and revising the final paper, Alberto	Participated in study design, statistical analysis and interpretation of data, revising the final paper, Claudia T-Gutierrez: Participated in design, study supervision and revising the final paper, Alberto	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Supervision|Writing - Review & Editing	YES
4627201	26526368	E Mateus	7	Participated in the study design, data collection, analysis and interpretation of data, Jubby	Participated in the study design, data collection, analysis and interpretation of data, Jubby	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
4627201	26526368	J Fonseca	7	Participated in the study design, data collection, analysis and interpretation of data and drafting the manuscript, Heidi	Participated in the study design, data collection, analysis and interpretation of data and drafting the manuscript, Heidi	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4627201	26526368	M Galvez	7	Participated in the data collection, analysis and interpretation of data, drafting the manuscript and revising the final paper, Diego	Participated in the data collection, analysis and interpretation of data, drafting the manuscript and revising the final paper, Diego	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
4627201	26526368	V Meerbeke	7	Participated in study design, study supervision, statistical analysis and interpretation of data, as well as drafting the manuscript and revising the final paper	Participated in study design, study supervision, statistical analysis and interpretation of data, as well as drafting the manuscript and revising the final paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
1797615	17327917	JS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1797615	17327917	JS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1797615	17327917	JS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1797615	17327917	MM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1797615	17327917	MM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1797615	17327917	MM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1797615	17327917	MM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1797615	17327917	WM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
6198166	30350345	All authors	2	participated in the winnipeg symposium and contributed to the manuscript revisions|contributed significantly to this study and have reviewed and approved the final version	participated in the winnipeg symposium and contributed to the manuscript revisions	Wrote the paper	Writing - Review & Editing	YES
6198166	30350345	All authors	2	participated in the winnipeg symposium and contributed to the manuscript revisions|contributed significantly to this study and have reviewed and approved the final version	contributed significantly to this study and have reviewed and approved the final version	-	-	NO
6198166	30350345	CJB	2	drafted this manuscript|led the discussions on varied bioinformatics issues at the symposium and summarized the consensus on the corresponding topics that were presented here	drafted this manuscript	Wrote the paper	Writing - Original Draft	YES
6198166	30350345	CJB	2	drafted this manuscript|led the discussions on varied bioinformatics issues at the symposium and summarized the consensus on the corresponding topics that were presented here	led the discussions on varied bioinformatics issues at the symposium and summarized the consensus on the corresponding topics that were presented here	-	Formal analysis	YES
6198166	30350345	EE	2	led the discussions on varied bioinformatics issues at the symposium and summarized the consensus on the corresponding topics that were presented here	led the discussions on varied bioinformatics issues at the symposium and summarized the consensus on the corresponding topics that were presented here	-	Formal analysis	YES
6198166	30350345	EM	2	led the discussions on varied bioinformatics issues at the symposium and summarized the consensus on the corresponding topics that were presented here	led the discussions on varied bioinformatics issues at the symposium and summarized the consensus on the corresponding topics that were presented here	-	Formal analysis	YES
6198166	30350345	ERL	2	led the discussions on varied bioinformatics issues at the symposium and summarized the consensus on the corresponding topics that were presented here	led the discussions on varied bioinformatics issues at the symposium and summarized the consensus on the corresponding topics that were presented here	-	Formal analysis	YES
6198166	30350345	GVD	2	conceived and initiated the project	conceived and initiated the project	Conceived and designed the experiments	Conceptualization	YES
6198166	30350345	HJ	2	conceived and initiated the project|drafted this manuscript	conceived and initiated the project	Conceived and designed the experiments	Conceptualization	YES
6198166	30350345	HJ	2	conceived and initiated the project|drafted this manuscript	drafted this manuscript	Wrote the paper	Writing - Original Draft	YES
6198166	30350345	MH	2	led the discussions on varied bioinformatics issues at the symposium and summarized the consensus on the corresponding topics that were presented here	led the discussions on varied bioinformatics issues at the symposium and summarized the consensus on the corresponding topics that were presented here	-	Formal analysis	YES
6198166	30350345	MNJ	2	conceived and initiated the project|drafted this manuscript|led the discussions on varied bioinformatics issues at the symposium and summarized the consensus on the corresponding topics that were presented here	conceived and initiated the project	Conceived and designed the experiments	Conceptualization	YES
6198166	30350345	MNJ	2	conceived and initiated the project|drafted this manuscript|led the discussions on varied bioinformatics issues at the symposium and summarized the consensus on the corresponding topics that were presented here	drafted this manuscript	Wrote the paper	Writing - Original Draft	YES
6198166	30350345	MNJ	2	conceived and initiated the project|drafted this manuscript|led the discussions on varied bioinformatics issues at the symposium and summarized the consensus on the corresponding topics that were presented here	led the discussions on varied bioinformatics issues at the symposium and summarized the consensus on the corresponding topics that were presented here	-	Formal analysis	YES
6198166	30350345	NP	2	drafted this manuscript	drafted this manuscript	Wrote the paper	Writing - Original Draft	YES
6198166	30350345	PS	2	conceived and initiated the project	conceived and initiated the project	Conceived and designed the experiments	Conceptualization	YES
6198166	30350345	RC	2	led the discussions on varied bioinformatics issues at the symposium and summarized the consensus on the corresponding topics that were presented here	led the discussions on varied bioinformatics issues at the symposium and summarized the consensus on the corresponding topics that were presented here	-	Formal analysis	YES
6198166	30350345	RH	2	conceived and initiated the project	conceived and initiated the project	Conceived and designed the experiments	Conceptualization	YES
6198166	30350345	RK	2	conceived and initiated the project|drafted this manuscript	conceived and initiated the project	Conceived and designed the experiments	Conceptualization	YES
6198166	30350345	RK	2	conceived and initiated the project|drafted this manuscript	drafted this manuscript	Wrote the paper	Writing - Original Draft	YES
6198166	30350345	RP	2	conceived and initiated the project	conceived and initiated the project	Conceived and designed the experiments	Conceptualization	YES
5650699	29085383	AH	2	was involved in designing the greenhouse experiment and the critical revision of the manuscript	was involved in designing the greenhouse experiment and the critical revision of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5650699	29085383	AK	2	conceived the study and contributed to the critical revision of the manuscript	conceived the study and contributed to the critical revision of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5650699	29085383	All authors	2	approved the final version of the manuscript	approved the final version of the manuscript	-	-	NO
5650699	29085383	KM	2	developed the rils|were involved in revision of the manuscript	developed the rils	-	-	NO
5650699	29085383	KM	2	developed the rils|were involved in revision of the manuscript	were involved in revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5650699	29085383	MC	2	was involved in conducting the experiment, recording observations and drafting the article	was involved in conducting the experiment, recording observations and drafting the article	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5650699	29085383	MD	2	were involved in revision of the manuscript	were involved in revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5650699	29085383	MN	2	developed the rils	developed the rils	-	-	NO
5650699	29085383	NAAS	2	was involved in conducting the experiment and recording observations	was involved in conducting the experiment and recording observations	Performed the experiments	Investigation	YES
5650699	29085383	NS	2	was involved in experimental analysis, interpretation of data and revising the manuscript	was involved in experimental analysis, interpretation of data and revising the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5650699	29085383	SD	2	was involved in experimental analysis, interpretation of data and revising the manuscript	was involved in experimental analysis, interpretation of data and revising the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4412194	25977877	AKB	2	conceived and designed the study|revised it critically for important intellectual content	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412194	25977877	AKB	2	conceived and designed the study|revised it critically for important intellectual content	revised it critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4412194	25977877	AlS	2	acquired the data	acquired the data	Performed the experiments	Investigation	YES
4412194	25977877	All authors	2	gave final approval of the version to be published and agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	gave final approval of the version to be published and agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	-	-	NO
4412194	25977877	AnS	2	conceived and designed the study|revised it critically for important intellectual content	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412194	25977877	AnS	2	conceived and designed the study|revised it critically for important intellectual content	revised it critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4412194	25977877	CB	2	acquired the data	acquired the data	Performed the experiments	Investigation	YES
4412194	25977877	CL	2	analyzed and interpreted the data	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
4412194	25977877	KH	2	conceived and designed the study|revised it critically for important intellectual content	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412194	25977877	KH	2	conceived and designed the study|revised it critically for important intellectual content	revised it critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4412194	25977877	KL	2	conceived and designed the study|revised it critically for important intellectual content	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412194	25977877	KL	2	conceived and designed the study|revised it critically for important intellectual content	revised it critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4412194	25977877	RAW	2	analyzed and interpreted the data	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5471809	28615065	All authors	PLoS52	read, commented and approved the final manuscript	read, commented and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5471809	28615065	BZ	PLoS52	performed statistical analyses|wrote the paper|participated in data analyses	performed statistical analyses	Analyzed the data	Formal analysis	YES
5471809	28615065	BZ	PLoS52	performed statistical analyses|wrote the paper|participated in data analyses	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5471809	28615065	BZ	PLoS52	performed statistical analyses|wrote the paper|participated in data analyses	participated in data analyses	Analyzed the data	Formal analysis	YES
5471809	28615065	HJG	PLoS52	participated in data analyses	participated in data analyses	Analyzed the data	Formal analysis	YES
5471809	28615065	HMN	PLoS52	participated in the design of the study and contributed to acquisition of data	participated in the design of the study and contributed to acquisition of data	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources	YES
5471809	28615065	HN	PLoS52	carried out quantification of fatty acids	carried out quantification of fatty acids	Performed the experiments	Investigation	YES
5471809	28615065	JYL	PLoS52	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5471809	28615065	LG	PLoS52	carried out quantification of fatty acids	carried out quantification of fatty acids	Performed the experiments	Investigation	YES
5471809	28615065	LPZ	PLoS52	participated in the design of the study and contributed to acquisition of data	participated in the design of the study and contributed to acquisition of data	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources	YES
5471809	28615065	LYX	PLoS52	conceived and designed the study|performed statistical analyses|wrote the paper|participated in data analyses|performed snp and gene annotation	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5471809	28615065	LYX	PLoS52	conceived and designed the study|performed statistical analyses|wrote the paper|participated in data analyses|performed snp and gene annotation	performed statistical analyses	Analyzed the data	Formal analysis	YES
5471809	28615065	LYX	PLoS52	conceived and designed the study|performed statistical analyses|wrote the paper|participated in data analyses|performed snp and gene annotation	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5471809	28615065	LYX	PLoS52	conceived and designed the study|performed statistical analyses|wrote the paper|participated in data analyses|performed snp and gene annotation	participated in data analyses	Analyzed the data	Formal analysis	YES
5471809	28615065	LYX	PLoS52	conceived and designed the study|performed statistical analyses|wrote the paper|participated in data analyses|performed snp and gene annotation	performed snp and gene annotation	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5471809	28615065	PG	PLoS52	carried out quantification of fatty acids	carried out quantification of fatty acids	Performed the experiments	Investigation	YES
5471809	28615065	WGZ	PLoS52	carried out quantification of fatty acids	carried out quantification of fatty acids	Performed the experiments	Investigation	YES
5471809	28615065	XG	PLoS52	carried out quantification of fatty acids	carried out quantification of fatty acids	Performed the experiments	Investigation	YES
5471809	28615065	YC	PLoS52	carried out quantification of fatty acids	carried out quantification of fatty acids	Performed the experiments	Investigation	YES
5471809	28615065	YG	PLoS52	participated in the design of the study and contributed to acquisition of data	participated in the design of the study and contributed to acquisition of data	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources	YES
5471809	28615065	YHL	PLoS52	participated in data analyses	participated in data analyses	Analyzed the data	Formal analysis	YES
5471809	28615065	ZZW	PLoS52	participated in data analyses	participated in data analyses	Analyzed the data	Formal analysis	YES
1797616	17299587	AL	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1797616	17299587	AL	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1797616	17299587	CW	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1797616	17299587	PC	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1797616	17299587	PC	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1797616	17299587	SF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1797616	17299587	SF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1797616	17299587	SF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1797616	17299587	SF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1797616	17299587	SR	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1797616	17299587	SR	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1797616	17299587	WG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1797616	17299587	WG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1797616	17299587	WG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4410937	25915547	BCC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4410937	25915547	BCC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4410937	25915547	CLZ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4410937	25915547	CLZ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4410937	25915547	CLZ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4410937	25915547	CLZ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4410937	25915547	DDH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4410937	25915547	NL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4410937	25915547	SLW	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4410937	25915547	SLW	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4410937	25915547	SLW	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4410937	25915547	WYP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4410937	25915547	XLC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4410937	25915547	XS	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4410937	25915547	XS	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4410937	25915547	XS	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4410937	25915547	ZY	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4410937	25915547	ZY	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4627202	26526501	Arambakkam Mamangam Subaraja	7	Executed the bench work and also involved in manuscript preparation	Executed the bench work and also involved in manuscript preparation	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4627202	26526501	J Vanisree	7	Conceived the work, designed, analysed the results and wrote the major part of the manuscript	Conceived the work, designed, analysed the results and wrote the major part of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
6198167	30350392	BK	2	conceptualized, designed and developed the protocol|implemented the research|statistically analysed the data|interpreted the findings of the data|wrote the first draft of the manuscript	conceptualized, designed and developed the protocol	Conceived and designed the experiments	Conceptualization|Methodology	YES
6198167	30350392	BK	2	conceptualized, designed and developed the protocol|implemented the research|statistically analysed the data|interpreted the findings of the data|wrote the first draft of the manuscript	implemented the research	Performed the experiments	Investigation	YES
6198167	30350392	BK	2	conceptualized, designed and developed the protocol|implemented the research|statistically analysed the data|interpreted the findings of the data|wrote the first draft of the manuscript	statistically analysed the data	Analyzed the data	Formal analysis	YES
6198167	30350392	BK	2	conceptualized, designed and developed the protocol|implemented the research|statistically analysed the data|interpreted the findings of the data|wrote the first draft of the manuscript	interpreted the findings of the data	Analyzed the data	Formal analysis	YES
6198167	30350392	BK	2	conceptualized, designed and developed the protocol|implemented the research|statistically analysed the data|interpreted the findings of the data|wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
6198167	30350392	CGE	2	implemented the research	implemented the research	Performed the experiments	Investigation	YES
6198167	30350392	CY	2	implemented the research|collected the data	implemented the research	Performed the experiments	Investigation	YES
6198167	30350392	CY	2	implemented the research|collected the data	collected the data	Performed the experiments	Investigation	YES
6198167	30350392	DE	2	implemented the research|collected the data|statistically analysed the data|interpreted the findings of the data|wrote the first draft of the manuscript	implemented the research	Performed the experiments	Investigation	YES
6198167	30350392	DE	2	implemented the research|collected the data|statistically analysed the data|interpreted the findings of the data|wrote the first draft of the manuscript	collected the data	Performed the experiments	Investigation	YES
6198167	30350392	DE	2	implemented the research|collected the data|statistically analysed the data|interpreted the findings of the data|wrote the first draft of the manuscript	statistically analysed the data	Analyzed the data	Formal analysis	YES
6198167	30350392	DE	2	implemented the research|collected the data|statistically analysed the data|interpreted the findings of the data|wrote the first draft of the manuscript	interpreted the findings of the data	Analyzed the data	Formal analysis	YES
6198167	30350392	DE	2	implemented the research|collected the data|statistically analysed the data|interpreted the findings of the data|wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
6198167	30350392	GM	2	conceptualized, designed and developed the protocol|implemented the research	conceptualized, designed and developed the protocol	Conceived and designed the experiments	Conceptualization|Methodology	YES
6198167	30350392	GM	2	conceptualized, designed and developed the protocol|implemented the research	implemented the research	Performed the experiments	Investigation	YES
6198167	30350392	IC	2	conceptualized, designed and developed the protocol|interpreted the findings of the data|wrote the first draft of the manuscript	conceptualized, designed and developed the protocol	Conceived and designed the experiments	Conceptualization|Methodology	YES
6198167	30350392	IC	2	conceptualized, designed and developed the protocol|interpreted the findings of the data|wrote the first draft of the manuscript	interpreted the findings of the data	Analyzed the data	Formal analysis	YES
6198167	30350392	IC	2	conceptualized, designed and developed the protocol|interpreted the findings of the data|wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
6198167	30350392	IZ	2	implemented the research	implemented the research	Performed the experiments	Investigation	YES
6198167	30350392	JG	2	interpreted the findings of the data	interpreted the findings of the data	Analyzed the data	Formal analysis	YES
6198167	30350392	KJ	2	conceptualized, designed and developed the protocol	conceptualized, designed and developed the protocol	Conceived and designed the experiments	Conceptualization|Methodology	YES
6198167	30350392	MN	2	implemented the research|collected the data|statistically analysed the data|interpreted the findings of the data	implemented the research	Performed the experiments	Investigation	YES
6198167	30350392	MN	2	implemented the research|collected the data|statistically analysed the data|interpreted the findings of the data	collected the data	Performed the experiments	Investigation	YES
6198167	30350392	MN	2	implemented the research|collected the data|statistically analysed the data|interpreted the findings of the data	statistically analysed the data	Analyzed the data	Formal analysis	YES
6198167	30350392	MN	2	implemented the research|collected the data|statistically analysed the data|interpreted the findings of the data	interpreted the findings of the data	Analyzed the data	Formal analysis	YES
6198167	30350392	MP	2	implemented the research	implemented the research	Performed the experiments	Investigation	YES
6198167	30350392	RT	2	conceptualized, designed and developed the protocol|interpreted the findings of the data|interpreted the findings of the data	conceptualized, designed and developed the protocol	Conceived and designed the experiments	Conceptualization|Methodology	YES
6198167	30350392	RT	2	conceptualized, designed and developed the protocol|interpreted the findings of the data|interpreted the findings of the data	interpreted the findings of the data	Analyzed the data	Formal analysis	YES
6198167	30350392	RT	2	conceptualized, designed and developed the protocol|interpreted the findings of the data|interpreted the findings of the data	interpreted the findings of the data	Analyzed the data	Formal analysis	YES
6198167	30350392	SMK	2	conceptualized, designed and developed the protocol|implemented the research|interpreted the findings of the data	conceptualized, designed and developed the protocol	Conceived and designed the experiments	Conceptualization|Methodology	YES
6198167	30350392	SMK	2	conceptualized, designed and developed the protocol|implemented the research|interpreted the findings of the data	implemented the research	Performed the experiments	Investigation	YES
6198167	30350392	SMK	2	conceptualized, designed and developed the protocol|implemented the research|interpreted the findings of the data	interpreted the findings of the data	Analyzed the data	Formal analysis	YES
4412195	25977879	ARS	2	contributed to the direct tissue oxygen measurements	contributed to the direct tissue oxygen measurements	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4412195	25977879	CT	2	imaging, direct tissue oxygen measurements, analysis and interpretation of the data, and preparation of the manuscript|imaging, and preparation of the manuscript	imaging, direct tissue oxygen measurements, analysis and interpretation of the data, and preparation of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Visualization|Writing - Original Draft	YES
4412195	25977879	CT	2	imaging, direct tissue oxygen measurements, analysis and interpretation of the data, and preparation of the manuscript|imaging, and preparation of the manuscript	imaging, and preparation of the manuscript	Analyzed the data|Wrote the paper	Visualization|Writing - Original Draft	YES
4412195	25977879	EL	2	contributed to the statistical analysis of the study data	contributed to the statistical analysis of the study data	Analyzed the data	Formal analysis	YES
4412195	25977879	HM	2	contributed to the study design and interpretation of the data and preparation of the manuscript	contributed to the study design and interpretation of the data and preparation of the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Original Draft	YES
4412195	25977879	OS	2	contributed to the synthesis of the tracer	contributed to the synthesis of the tracer	-	-	NO
4412195	25977879	RG	2	contributed to the study design and supervision of cell culturing	contributed to the study design and supervision of cell culturing	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Supervision	YES
4412195	25977879	SF	2	contributed to the synthesis of the tracer	contributed to the synthesis of the tracer	-	-	NO
4412195	25977879	TJG	2	contributed to the conception and design of the study, to the experimental procedures, to the analysis and interpretation of the data, as well as to the preparation of the manuscript	contributed to the conception and design of the study, to the experimental procedures, to the analysis and interpretation of the data, as well as to the preparation of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
5885778	29675167	M.K.	2	performed the magnetometric and hf-epr measurements and analyses	performed the magnetometric and hf-epr measurements and analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5885778	29675167	M.P.	2	performed the magnetometric and hf-epr measurements and analyses	performed the magnetometric and hf-epr measurements and analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5885778	29675167	M.R.R.	2	performed the electrochemical experiments	performed the electrochemical experiments	Performed the experiments	Investigation	YES
5885778	29675167	P.Z.	2	synthesized and characterized the complexes|performed the magnetometric and hf-epr measurements and analyses	synthesized and characterized the complexes	Performed the experiments	Investigation	YES
5885778	29675167	P.Z.	2	synthesized and characterized the complexes|performed the magnetometric and hf-epr measurements and analyses	performed the magnetometric and hf-epr measurements and analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5885778	29675167	S.L.	2	performed and analyzed the q-band pulsed epr measurements	performed and analyzed the q-band pulsed epr measurements	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5885778	29675167	W.F.	2	performed the crystallographic investigation	performed the crystallographic investigation	Performed the experiments	Investigation	YES
1797623	17299583	CB	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1797623	17299583	CB	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1797623	17299583	EW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1797623	17299583	EW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1797623	17299583	EW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1797623	17299583	FP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1797623	17299583	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1797623	17299583	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1797623	17299583	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1797623	17299583	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1797623	17299583	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1797623	17299583	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1797623	17299583	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1797623	17299583	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1797623	17299583	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1797623	17299583	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1797623	17299583	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1797623	17299583	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1797623	17299583	RN	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1797623	17299583	RN	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4412196	25977880	AKB	2	conceived the study|revised it critically for important intellectual content	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4412196	25977880	AKB	2	conceived the study|revised it critically for important intellectual content	revised it critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4412196	25977880	AlS	2	acquired the data|were involved in the drafting of the manuscript	acquired the data	Performed the experiments	Investigation	YES
4412196	25977880	AlS	2	acquired the data|were involved in the drafting of the manuscript	were involved in the drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
4412196	25977880	All authors	2	gave final approval of the version to be published and agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	gave final approval of the version to be published and agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	-	-	NO
4412196	25977880	AnS	2	conceived the study|revised it critically for important intellectual content	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4412196	25977880	AnS	2	conceived the study|revised it critically for important intellectual content	revised it critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4412196	25977880	CB	2	acquired the data|were involved in the drafting of the manuscript|revised it critically for important intellectual content	acquired the data	Performed the experiments	Investigation	YES
4412196	25977880	CB	2	acquired the data|were involved in the drafting of the manuscript|revised it critically for important intellectual content	were involved in the drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
4412196	25977880	CB	2	acquired the data|were involved in the drafting of the manuscript|revised it critically for important intellectual content	revised it critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4412196	25977880	CL	2	conceived the study|analyzed and interpreted the data|were involved in the drafting of the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4412196	25977880	CL	2	conceived the study|analyzed and interpreted the data|were involved in the drafting of the manuscript	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
4412196	25977880	CL	2	conceived the study|analyzed and interpreted the data|were involved in the drafting of the manuscript	were involved in the drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
4412196	25977880	DOM	2	analyzed and interpreted the data	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
4412196	25977880	HH	2	analyzed and interpreted the data	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
4412196	25977880	KH	2	conceived the study|revised it critically for important intellectual content	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4412196	25977880	KH	2	conceived the study|revised it critically for important intellectual content	revised it critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4412196	25977880	KL	2	conceived the study|revised it critically for important intellectual content	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4412196	25977880	KL	2	conceived the study|revised it critically for important intellectual content	revised it critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4412196	25977880	MAA	2	conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4412196	25977880	RAB	2	revised it critically for important intellectual content	revised it critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4412196	25977880	RAW	2	conceived the study|analyzed and interpreted the data|were involved in the drafting of the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4412196	25977880	RAW	2	conceived the study|analyzed and interpreted the data|were involved in the drafting of the manuscript	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
4412196	25977880	RAW	2	conceived the study|analyzed and interpreted the data|were involved in the drafting of the manuscript	were involved in the drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
4792406	26953173	All authors	2	gave final approval for publication	gave final approval for publication	-	-	NO
4792406	26953173	F.Q.	2	motivated the study and provided ideas, helped design the study, and helped draft and revise the manuscript	motivated the study and provided ideas, helped design the study, and helped draft and revise the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
4792406	26953173	J.F.	2	obtained model data, carried out the majority of calculation and analysis, and helped draft the manuscript	obtained model data, carried out the majority of calculation and analysis, and helped draft the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4792406	26953173	Z.M.T.	2	motivated the study and provided ideas, helped design the study, and helped draft and revise the manuscript	motivated the study and provided ideas, helped design the study, and helped draft and revise the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
4792406	26953173	Z.W.	2	was the main designer and coordinated the study, carried out a portion of calculation and analysis, drafted and revised the manuscript	was the main designer and coordinated the study, carried out a portion of calculation and analysis, drafted and revised the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Project administration|Writing - Original Draft|Writing - Review & Editing	YES
4410938	25915765	BHS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4410938	25915765	BHS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4410938	25915765	GNY	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4410938	25915765	GNY	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4410938	25915765	JKK	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4410938	25915765	JKK	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4410938	25915765	JMK	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4410938	25915765	JMK	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4410938	25915765	SIY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4410938	25915765	SIY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4410938	25915765	SIY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4410938	25915765	SIY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4410938	25915765	SJB	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4410938	25915765	YML	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4410938	25915765	YML	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4410938	25915765	YML	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4627203	26526627	Geeta Shrauff	7	Involved in the conception, design and conducted the study, reviewed each draft of the manuscript	Involved in the conception, design and conducted the study, reviewed each draft of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
4627203	26526627	Rakesh Gupta	7	Involved in the clinical examination of some patients	Involved in the clinical examination of some patients	Performed the experiments	Investigation	YES
6198168	30350406	All authors	2	reviewed the manuscript critically for intellectual content	reviewed the manuscript critically for intellectual content	Wrote the paper	Writing - Review & Editing	YES
6198168	30350406	BDD	2	the hptn study team contributed to developing the study concept and design	the hptn study team contributed to developing the study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6198168	30350406	BH	2	contributed to data collection|assisted with data analysis and results interpretation	contributed to data collection	Performed the experiments	Investigation	YES
6198168	30350406	BH	2	contributed to data collection|assisted with data analysis and results interpretation	assisted with data analysis and results interpretation	Analyzed the data	Formal analysis	YES
6198168	30350406	CVA	2	contributed to data collection	contributed to data collection	Performed the experiments	Investigation	YES
6198168	30350406	DD	2	the hptn study team contributed to developing the study concept and design|contributed to data collection	the hptn study team contributed to developing the study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6198168	30350406	DD	2	the hptn study team contributed to developing the study concept and design|contributed to data collection	contributed to data collection	Performed the experiments	Investigation	YES
6198168	30350406	ELH	2	the hptn study team contributed to developing the study concept and design|contributed to data collection	the hptn study team contributed to developing the study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6198168	30350406	ELH	2	the hptn study team contributed to developing the study concept and design|contributed to data collection	contributed to data collection	Performed the experiments	Investigation	YES
6198168	30350406	EMP-M	2	contributed to data collection	contributed to data collection	Performed the experiments	Investigation	YES
6198168	30350406	HS	2	contributed to data collection	contributed to data collection	Performed the experiments	Investigation	YES
6198168	30350406	IFH	2	the hptn study team had overall responsibility for implementing the study, and conceived and designed the study, analysed the data and led the manuscript writing|assisted with data analysis and results interpretation|the hptn study team contributed to drafting the manuscript	the hptn study team had overall responsibility for implementing the study, and conceived and designed the study, analysed the data and led the manuscript writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
6198168	30350406	IFH	2	the hptn study team had overall responsibility for implementing the study, and conceived and designed the study, analysed the data and led the manuscript writing|assisted with data analysis and results interpretation|the hptn study team contributed to drafting the manuscript	assisted with data analysis and results interpretation	Analyzed the data	Formal analysis	YES
6198168	30350406	IFH	2	the hptn study team had overall responsibility for implementing the study, and conceived and designed the study, analysed the data and led the manuscript writing|assisted with data analysis and results interpretation|the hptn study team contributed to drafting the manuscript	the hptn study team contributed to drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
6198168	30350406	JPL	2	the hptn study team contributed to developing the study concept and design	the hptn study team contributed to developing the study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6198168	30350406	KD	2	contributed to data collection	contributed to data collection	Performed the experiments	Investigation	YES
6198168	30350406	KEL	2	the hptn study team had overall responsibility for implementing the study, and conceived and designed the study, analysed the data and led the manuscript writing|assisted with data analysis and results interpretation|the hptn study team contributed to drafting the manuscript	the hptn study team had overall responsibility for implementing the study, and conceived and designed the study, analysed the data and led the manuscript writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
6198168	30350406	KEL	2	the hptn study team had overall responsibility for implementing the study, and conceived and designed the study, analysed the data and led the manuscript writing|assisted with data analysis and results interpretation|the hptn study team contributed to drafting the manuscript	assisted with data analysis and results interpretation	Analyzed the data	Formal analysis	YES
6198168	30350406	KEL	2	the hptn study team had overall responsibility for implementing the study, and conceived and designed the study, analysed the data and led the manuscript writing|assisted with data analysis and results interpretation|the hptn study team contributed to drafting the manuscript	the hptn study team contributed to drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
6198168	30350406	KRM	2	assisted with data analysis and results interpretation	assisted with data analysis and results interpretation	Analyzed the data	Formal analysis	YES
6198168	30350406	LE	2	the hptn study team contributed to developing the study concept and design|contributed to data collection	the hptn study team contributed to developing the study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6198168	30350406	LE	2	the hptn study team contributed to developing the study concept and design|contributed to data collection	contributed to data collection	Performed the experiments	Investigation	YES
6198168	30350406	LES	2	the hptn study team contributed to developing the study concept and design|contributed to data collection	the hptn study team contributed to developing the study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6198168	30350406	LES	2	the hptn study team contributed to developing the study concept and design|contributed to data collection	contributed to data collection	Performed the experiments	Investigation	YES
6198168	30350406	LM	2	the hptn study team contributed to developing the study concept and design|contributed to data collection	the hptn study team contributed to developing the study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6198168	30350406	LM	2	the hptn study team contributed to developing the study concept and design|contributed to data collection	contributed to data collection	Performed the experiments	Investigation	YES
6198168	30350406	MGH	2	assisted with data analysis and results interpretation	assisted with data analysis and results interpretation	Analyzed the data	Formal analysis	YES
6198168	30350406	NS	2	the hptn study team contributed to developing the study concept and design	the hptn study team contributed to developing the study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6198168	30350406	NVV	2	the hptn study team contributed to developing the study concept and design	the hptn study team contributed to developing the study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6198168	30350406	OZ	2	contributed to data collection	contributed to data collection	Performed the experiments	Investigation	YES
6198168	30350406	PR	2	contributed to data collection	contributed to data collection	Performed the experiments	Investigation	YES
6198168	30350406	RS	2	the hptn study team contributed to developing the study concept and design|contributed to data collection	the hptn study team contributed to developing the study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6198168	30350406	RS	2	the hptn study team contributed to developing the study concept and design|contributed to data collection	contributed to data collection	Performed the experiments	Investigation	YES
6198168	30350406	SAR	2	assisted with data analysis and results interpretation	assisted with data analysis and results interpretation	Analyzed the data	Formal analysis	YES
6198168	30350406	SD	2	contributed to data collection|contributed to data collection	contributed to data collection	Performed the experiments	Investigation	YES
6198168	30350406	SD	2	contributed to data collection|contributed to data collection	contributed to data collection	Performed the experiments	Investigation	YES
6198168	30350406	SHE	2	contributed to data collection	contributed to data collection	Performed the experiments	Investigation	YES
6198168	30350406	SR	2	contributed to data collection	contributed to data collection	Performed the experiments	Investigation	YES
6198168	30350406	TK	2	contributed to data collection	contributed to data collection	Performed the experiments	Investigation	YES
6198168	30350406	TVH	2	contributed to data collection	contributed to data collection	Performed the experiments	Investigation	YES
6198168	30350406	VFG	2	contributed to data collection	contributed to data collection	Performed the experiments	Investigation	YES
6198168	30350406	WC	2	contributed to data collection	contributed to data collection	Performed the experiments	Investigation	YES
6198168	30350406	WCM	2	the hptn study team had overall responsibility for implementing the study, and conceived and designed the study, analysed the data and led the manuscript writing|the hptn study team contributed to developing the study concept and design|assisted with data analysis and results interpretation|the hptn study team contributed to drafting the manuscript	the hptn study team had overall responsibility for implementing the study, and conceived and designed the study, analysed the data and led the manuscript writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
6198168	30350406	WCM	2	the hptn study team had overall responsibility for implementing the study, and conceived and designed the study, analysed the data and led the manuscript writing|the hptn study team contributed to developing the study concept and design|assisted with data analysis and results interpretation|the hptn study team contributed to drafting the manuscript	the hptn study team contributed to developing the study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6198168	30350406	WCM	2	the hptn study team had overall responsibility for implementing the study, and conceived and designed the study, analysed the data and led the manuscript writing|the hptn study team contributed to developing the study concept and design|assisted with data analysis and results interpretation|the hptn study team contributed to drafting the manuscript	assisted with data analysis and results interpretation	Analyzed the data	Formal analysis	YES
6198168	30350406	WCM	2	the hptn study team had overall responsibility for implementing the study, and conceived and designed the study, analysed the data and led the manuscript writing|the hptn study team contributed to developing the study concept and design|assisted with data analysis and results interpretation|the hptn study team contributed to drafting the manuscript	the hptn study team contributed to drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
6198168	30350406	ZD	2	contributed to data collection	contributed to data collection	Performed the experiments	Investigation	YES
5471912	28615048	ICJ	2	conceived the project|supervised the experiments|designed the experiments and interpreted data|wrote the manuscript	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5471912	28615048	ICJ	2	conceived the project|supervised the experiments|designed the experiments and interpreted data|wrote the manuscript	supervised the experiments	-	Supervision	YES
5471912	28615048	ICJ	2	conceived the project|supervised the experiments|designed the experiments and interpreted data|wrote the manuscript	designed the experiments and interpreted data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5471912	28615048	ICJ	2	conceived the project|supervised the experiments|designed the experiments and interpreted data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5471912	28615048	JJ	2	performed the de novo assembly of rna seq	performed the de novo assembly of rna seq	Performed the experiments	Investigation	YES
5471912	28615048	NHC	2	conceived the project|designed the experiments and interpreted data	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5471912	28615048	NHC	2	conceived the project|designed the experiments and interpreted data	designed the experiments and interpreted data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5471912	28615048	RS	2	conceived the project|designed the experiments and interpreted data	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5471912	28615048	RS	2	conceived the project|designed the experiments and interpreted data	designed the experiments and interpreted data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5471912	28615048	SD	2	analyzed the transcriptome data|designed the experiments and interpreted data|performed the molecular and biochemical experiments|wrote the manuscript	analyzed the transcriptome data	Analyzed the data	Formal analysis	YES
5471912	28615048	SD	2	analyzed the transcriptome data|designed the experiments and interpreted data|performed the molecular and biochemical experiments|wrote the manuscript	designed the experiments and interpreted data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5471912	28615048	SD	2	analyzed the transcriptome data|designed the experiments and interpreted data|performed the molecular and biochemical experiments|wrote the manuscript	performed the molecular and biochemical experiments	Performed the experiments	Investigation	YES
5471912	28615048	SD	2	analyzed the transcriptome data|designed the experiments and interpreted data|performed the molecular and biochemical experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5471912	28615048	VS	2	analyzed the transcriptome data	analyzed the transcriptome data	Analyzed the data	Formal analysis	YES
4412375	25977876	AS	2	contributed to the design of the study, acquired, analysed and interpreted the pet data and histological and immunohistochemical stainings|drafted the manuscript	contributed to the design of the study, acquired, analysed and interpreted the pet data and histological and immunohistochemical stainings	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Methodology|Resources	YES
4412375	25977876	AS	2	contributed to the design of the study, acquired, analysed and interpreted the pet data and histological and immunohistochemical stainings|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4412375	25977876	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4412375	25977876	FL	2	participated in the immunohistochemical stainings and performance of pet experiments	participated in the immunohistochemical stainings and performance of pet experiments	Performed the experiments	Investigation	YES
4412375	25977876	GF	2	participated in the design of the animal studies and revised the manuscript critically	participated in the design of the animal studies and revised the manuscript critically	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
4412375	25977876	JR	2	participated in the design of the study and carried out in vitro pet experiments|contributed to the conception, design and coordination of the study, revised the manuscript critically for its intellectual content and gave final approval for the published version	participated in the design of the study and carried out in vitro pet experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4412375	25977876	JR	2	participated in the design of the study and carried out in vitro pet experiments|contributed to the conception, design and coordination of the study, revised the manuscript critically for its intellectual content and gave final approval for the published version	contributed to the conception, design and coordination of the study, revised the manuscript critically for its intellectual content and gave final approval for the published version	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Review & Editing	YES
4412375	25977876	MHS	2	contributed to the conception, design and coordination of the study, revised the manuscript critically for its intellectual content and gave final approval for the published version|helped to draft the manuscript	contributed to the conception, design and coordination of the study, revised the manuscript critically for its intellectual content and gave final approval for the published version	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Review & Editing	YES
4412375	25977876	MHS	2	contributed to the conception, design and coordination of the study, revised the manuscript critically for its intellectual content and gave final approval for the published version|helped to draft the manuscript	helped to draft the manuscript	Wrote the paper	Writing - Original Draft	YES
4412375	25977876	MS	2	participated in the design of the animal studies and revised the manuscript critically|drafted and revised the manuscript critically for its intellectual content	participated in the design of the animal studies and revised the manuscript critically	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
4412375	25977876	MS	2	participated in the design of the animal studies and revised the manuscript critically|drafted and revised the manuscript critically for its intellectual content	drafted and revised the manuscript critically for its intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4412375	25977876	OS	2	contributed to the conception, design and coordination of the study, revised the manuscript critically for its intellectual content and gave final approval for the published version	contributed to the conception, design and coordination of the study, revised the manuscript critically for its intellectual content and gave final approval for the published version	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Review & Editing	YES
4792408	26953182	All authors	2	gave final approval for publication	gave final approval for publication	-	-	NO
4792408	26953182	D.D.	2	participated in the open ocean field experiment and data analysis	participated in the open ocean field experiment and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4792408	26953182	F.Q.	2	proposed the research idea on wave-turbulence interaction, designed the road map of the present research, proposed the new parametrization scheme for vertical mixing and drafted the manuscript	proposed the research idea on wave-turbulence interaction, designed the road map of the present research, proposed the new parametrization scheme for vertical mixing and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
4792408	26953182	J.D.	2	carried out the holo-hilbert spectral analysis for the field measurements	carried out the holo-hilbert spectral analysis for the field measurements	Performed the experiments	Investigation	YES
4792408	26953182	Y.Y.	2	proposed the research idea on wave-turbulence interaction, designed the road map of the present research, proposed the new parametrization scheme for vertical mixing and drafted the manuscript	proposed the research idea on wave-turbulence interaction, designed the road map of the present research, proposed the new parametrization scheme for vertical mixing and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
4792408	26953182	Z.S.	2	carried out numerical experiments to test the sensitivity of the wave-induced vertical mixing to different ocean circulation models	carried out numerical experiments to test the sensitivity of the wave-induced vertical mixing to different ocean circulation models	Performed the experiments	Formal analysis|Investigation|Methodology	YES
1797824	17327918	AN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1797824	17327918	AN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1797824	17327918	AN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1797824	17327918	CN	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1797824	17327918	MA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1797824	17327918	MA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1797824	17327918	MA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1797824	17327918	MA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1797824	17327918	MA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1797824	17327918	MS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1797824	17327918	MS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1797824	17327918	MS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1797824	17327918	PR	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1797824	17327918	PR	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1797824	17327918	PR	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1797824	17327918	RW	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1797824	17327918	RW	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1797824	17327918	RW	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5650975	29089950	AD	2	contributed to data analysis, data interpretation, drafting the work, and final approval of the version	contributed to data analysis, data interpretation, drafting the work, and final approval of the version	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5650975	29089950	FT	2	contributed to data collection, data analysis, data interpretation, drafting the work, and final approval of the version	contributed to data collection, data analysis, data interpretation, drafting the work, and final approval of the version	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5650975	29089950	KH	2	contributed to data collection, data analysis, data interpretation, drafting the work, and final approval of the version	contributed to data collection, data analysis, data interpretation, drafting the work, and final approval of the version	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5650975	29089950	MD	2	contributed to data analysis, data interpretation, drafting the work, and final approval of the version	contributed to data analysis, data interpretation, drafting the work, and final approval of the version	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5650975	29089950	MH	2	contributed to the conception or design of the work, data analysis, data interpretation, writing the draft manuscript, and final approval of the version	contributed to the conception or design of the work, data analysis, data interpretation, writing the draft manuscript, and final approval of the version	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Resources|Writing - Original Draft	YES
5650975	29089950	SO	2	contributed to data analysis, data interpretation, drafting the work, and final approval of the version	contributed to data analysis, data interpretation, drafting the work, and final approval of the version	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5650975	29089950	SY	2	contributed to data analysis, data interpretation, drafting the work, and final approval of the version	contributed to data analysis, data interpretation, drafting the work, and final approval of the version	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5650975	29089950	TN	2	contributed to data collection, data analysis, and writing the draft manuscript	contributed to data collection, data analysis, and writing the draft manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4627204	26526736	PI	5	executed study plan	executed study plan	Performed the experiments	Investigation	YES
5651006	29089953	AP	2	prepared the research topic	prepared the research topic	-	-	NO
5651006	29089953	All the authors	2	edited the manuscripts|read and approved the editorial	edited the manuscripts	Wrote the paper	Writing - Review & Editing	YES
5651006	29089953	All the authors	2	edited the manuscripts|read and approved the editorial	read and approved the editorial	-	-	NO
5651006	29089953	DL	2	prepared the research topic	prepared the research topic	-	-	NO
5651006	29089953	FA	2	invited the authors and wrote the editorial	invited the authors and wrote the editorial	Wrote the paper	Writing - Original Draft	YES
5651006	29089953	MB	2	prepared the research topic	prepared the research topic	-	-	NO
4410939	25915942	AR	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4410939	25915942	AR	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4410939	25915942	AZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4410939	25915942	CD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4410939	25915942	CD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4410939	25915942	CD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4410939	25915942	EB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4410939	25915942	GB	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4410939	25915942	GL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4410939	25915942	GL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4410939	25915942	GL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4410939	25915942	LT	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4410939	25915942	LT	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4410939	25915942	LT	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4410939	25915942	MZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4410939	25915942	SC	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4410939	25915942	SC	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4792411	26953184	All authors	2	developed and contributed to the writing and editing of the manuscript	developed and contributed to the writing and editing of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4792411	26953184	P.D.	2	developed the numerical implementation and carried out the associated experiments	developed the numerical implementation and carried out the associated experiments	Performed the experiments	Formal analysis|Investigation	YES
4792411	26953184	P.F.	2	conceived of writing the manuscript|developed the numerical implementation and carried out the associated experiments	conceived of writing the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4792411	26953184	P.F.	2	conceived of writing the manuscript|developed the numerical implementation and carried out the associated experiments	developed the numerical implementation and carried out the associated experiments	Performed the experiments	Formal analysis|Investigation	YES
4792411	26953184	S.M.	2	conceived of writing the manuscript|developed the ridge-based method and carried out associated experiments	conceived of writing the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4792411	26953184	S.M.	2	conceived of writing the manuscript|developed the ridge-based method and carried out associated experiments	developed the ridge-based method and carried out associated experiments	Performed the experiments	Investigation|Methodology	YES
4792411	26953184	S.M.c.L.	2	conceived of writing the manuscript	conceived of writing the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4792411	26953184	T.O.	2	developed the ridge-based method and carried out associated experiments	developed the ridge-based method and carried out associated experiments	Performed the experiments	Investigation|Methodology	YES
1797825	17318257	AD	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1797825	17318257	EM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1797825	17318257	EM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1797825	17318257	EM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1797825	17318257	EM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1797825	17318257	IM	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1797825	17318257	IM	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1797825	17318257	SW	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5472924	28619070	AMR	2	edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5472924	28619070	AYR	2	isolated the dna and fingerprinted the germplasm accessions	isolated the dna and fingerprinted the germplasm accessions	Performed the experiments	Investigation	YES
5472924	28619070	DNA	2	finger printing and wrote the part of manuscript	finger printing and wrote the part of manuscript	Wrote the paper	Writing - Original Draft	YES
5472924	28619070	HB	2	analysed c4 pathway genes	analysed c4 pathway genes	-	-	NO
5472924	28619070	HCL	2	helped in project execution and edited the manuscript	helped in project execution and edited the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5472924	28619070	MDS	2	performed the orthomcl analysis and helped in writing the manuscript	performed the orthomcl analysis and helped in writing the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5472924	28619070	NCBI	2	prepared all tables, figures and wrote the manuscript	prepared all tables, figures and wrote the manuscript	Wrote the paper	Visualization|Writing - Original Draft	YES
5472924	28619070	SH	2	planned and conceived the project, wrote the project proposal, fund acquisition, interacted with sequencing providers and edited the manuscript	planned and conceived the project, wrote the project proposal, fund acquisition, interacted with sequencing providers and edited the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Funding acquisition|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5472924	28619070	UG	2	isolated the dna and fingerprinted the germplasm accessions	isolated the dna and fingerprinted the germplasm accessions	Performed the experiments	Investigation	YES
5651024	29089949	CLY	2	revised it critically for important intellectual content	revised it critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5651024	29089949	CQY	2	approved the version to be published	approved the version to be published	-	-	NO
5651024	29089949	GX	2	revised it critically for important intellectual content	revised it critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5651024	29089949	JC	2	approved the version to be published	approved the version to be published	-	-	NO
5651024	29089949	JZ	2	revised it critically for important intellectual content	revised it critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5651024	29089949	QM	2	revised it critically for important intellectual content	revised it critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5651024	29089949	WF	2	revised it critically for important intellectual content	revised it critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5651024	29089949	WZ	2	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5651024	29089949	XC	2	designed the experiments|revised it critically for important intellectual content	designed the experiments	Conceived and designed the experiments	Methodology	YES
5651024	29089949	XC	2	designed the experiments|revised it critically for important intellectual content	revised it critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5651024	29089949	XW	2	revised it critically for important intellectual content	revised it critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5651024	29089949	YD	2	designed the experiments|participated in data analysis and wrote the article	designed the experiments	Conceived and designed the experiments	Methodology	YES
5651024	29089949	YD	2	designed the experiments|participated in data analysis and wrote the article	participated in data analysis and wrote the article	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5651024	29089949	YY	2	revised it critically for important intellectual content	revised it critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4627205	26526864	Akshay Anand	7	Made substantial contributions to conception and design of manuscript, and gave final approval for publication of manuscript	Made substantial contributions to conception and design of manuscript, and gave final approval for publication of manuscript	Conceived and designed the experiments	Conceptualization	YES
4627205	26526864	Keshav Thakur	7	Has been involved in drafting the manuscript	Has been involved in drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
4410940	25915905	AD	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4410940	25915905	AD	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4410940	25915905	AD	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4410940	25915905	AVH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4410940	25915905	AVH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4410940	25915905	AVH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4410940	25915905	AVH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4410940	25915905	AVH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4410940	25915905	KU	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4410940	25915905	KU	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4410940	25915905	KU	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4410940	25915905	PT	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4410940	25915905	PT	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4410940	25915905	TO	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4410940	25915905	TO	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4410940	25915905	TO	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4410940	25915905	VP	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4410940	25915905	VP	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4410940	25915905	VP	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4410940	25915905	YR	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4410940	25915905	YR	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3296955	22505932	Beibei Chen	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
3296955	22505932	Bo Zhang	2	designed the study|performed all the experiments	designed the study	Conceived and designed the experiments	Methodology	YES
3296955	22505932	Bo Zhang	2	designed the study|performed all the experiments	performed all the experiments	Performed the experiments	Investigation	YES
3296955	22505932	Runsheng Chen	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
3296955	22505932	Tao Wu	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
3296955	22505932	Xiaopeng Zhu	2	provided technical suggestions	provided technical suggestions	-	-	NO
1800344	17327919	AS	PLoS5	Contributed reagents/materials/analysis tools|Assisted in writing the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1800344	17327919	AS	PLoS5	Contributed reagents/materials/analysis tools|Assisted in writing the paper	Assisted in writing the paper	Wrote the paper	Writing - Original Draft	YES
1800344	17327919	ED	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1800344	17327919	IM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1800344	17327919	IM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1800344	17327919	IM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1800344	17327919	IM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1800344	17327919	IM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1800344	17327919	OS	PLoS5	Contributed reagents/materials/analysis tools|Assisted in writing the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1800344	17327919	OS	PLoS5	Contributed reagents/materials/analysis tools|Assisted in writing the paper	Assisted in writing the paper	Wrote the paper	Writing - Original Draft	YES
1800344	17327919	TB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1800344	17327919	TB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1800344	17327919	TB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1800344	17327919	TB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1800344	17327919	TB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1800344	17327919	VG	PLoS5	Contributed reagents/materials/analysis tools|Assisted in analyzing the data	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1800344	17327919	VG	PLoS5	Contributed reagents/materials/analysis tools|Assisted in analyzing the data	Assisted in analyzing the data	Analyzed the data	Formal analysis	YES
4627206	26527042	Devi Pravin Salunke	7	Design and concept and collection of data, Sushanta	Design and concept and collection of data, Sushanta	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
4627206	26527042	K Sahoo	7	Collection of data	Collection of data	Performed the experiments	Investigation	YES
4627206	26527042	Mandeep Ghuman	7	Collection of data	Collection of data	Performed the experiments	Investigation	YES
4627206	26527042	P Patra	7	Manuscript drafting	Manuscript drafting	Wrote the paper	Writing - Original Draft	YES
5651032	29089952	AF	PLoS52	analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5651032	29089952	AF	PLoS52	analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5651032	29089952	All authors	PLoS52	reviewed and approved the final manuscript	reviewed and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5651032	29089952	BM	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5651032	29089952	CC-W	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5651032	29089952	CS	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5651032	29089952	CS	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5651032	29089952	DB	PLoS52	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5651032	29089952	GP	PLoS52	designed the experiments|analyzed the data	designed the experiments	Conceived and designed the experiments	Methodology	YES
5651032	29089952	GP	PLoS52	designed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5651032	29089952	JC	PLoS52	designed the experiments|wrote the paper	designed the experiments	Conceived and designed the experiments	Methodology	YES
5651032	29089952	JC	PLoS52	designed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5651032	29089952	KR	PLoS52	designed the experiments|wrote the paper	designed the experiments	Conceived and designed the experiments	Methodology	YES
5651032	29089952	KR	PLoS52	designed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5651032	29089952	MG	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5651032	29089952	ML	PLoS52	analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5651032	29089952	ML	PLoS52	analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5651032	29089952	QW	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5651032	29089952	RM	PLoS52	performed the experiments|analyzed the data|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5651032	29089952	RM	PLoS52	performed the experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5651032	29089952	RM	PLoS52	performed the experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5651032	29089952	RMconceived	PLoS52	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
4792412	26953180	A.C.C.Y.	2	contributed in discussions to perfect the high-dimensional approach	contributed in discussions to perfect the high-dimensional approach	-	-	NO
4792412	26953180	C.-H.J.	2	participated in validating the spectral models with various datasets	participated in validating the spectral models with various datasets	Performed the experiments	Methodology|Validation	YES
4792412	26953180	C.-L.K.	2	participated in validating the spectral models with various datasets	participated in validating the spectral models with various datasets	Performed the experiments	Methodology|Validation	YES
4792412	26953180	C.K.P.	2	participated in validating the spectral models with various datasets	participated in validating the spectral models with various datasets	Performed the experiments	Methodology|Validation	YES
4792412	26953180	D.J.	2	programmed the algorithm	programmed the algorithm	Contributed reagents/materials/analysis tools	Software	YES
4792412	26953180	H.-C.C.	2	programmed the algorithm	programmed the algorithm	Contributed reagents/materials/analysis tools	Software	YES
4792412	26953180	J.H.M.	2	provided some data in the tests	provided some data in the tests	Contributed reagents/materials/analysis tools	Resources	YES
4792412	26953180	J.R.Y.	2	programmed the algorithm	programmed the algorithm	Contributed reagents/materials/analysis tools	Software	YES
4792412	26953180	K.H.	2	contributed in discussions to perfect the high-dimensional approach	contributed in discussions to perfect the high-dimensional approach	-	-	NO
4792412	26953180	S.R.L.	2	participated in validating the spectral models with various datasets|also contributed in writing, as well as drafting the figures	participated in validating the spectral models with various datasets	Performed the experiments	Methodology|Validation	YES
4792412	26953180	S.R.L.	2	participated in validating the spectral models with various datasets|also contributed in writing, as well as drafting the figures	also contributed in writing, as well as drafting the figures	Wrote the paper	Visualization|Writing - Original Draft	YES
4792412	26953180	W.-K.L.	2	participated in validating the spectral models with various datasets	participated in validating the spectral models with various datasets	Performed the experiments	Methodology|Validation	YES
4792412	26953180	Y.-H.W.	2	participated in validating the spectral models with various datasets	participated in validating the spectral models with various datasets	Performed the experiments	Methodology|Validation	YES
4792412	26953180	Z.W.	2	contributed in discussions to perfect the high-dimensional approach	contributed in discussions to perfect the high-dimensional approach	-	-	NO
4561113	26366410	All authors	2	participated in the design and analysis of the literature and review of the paper	participated in the design and analysis of the literature and review of the paper	Conceived and designed the experiments|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4561113	26366410	Igor Malyshev	2	generated the idea and wrote a draft of the paper	generated the idea and wrote a draft of the paper	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
4561113	26366410	Yuri Malyshev	2	contributed to the productive discussion, rewriting, and improvement of the paper	contributed to the productive discussion, rewriting, and improvement of the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5474855	28625162	AB	2	conceived and designed the tobacco genome study	conceived and designed the tobacco genome study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5474855	28625162	ADE	2	were involved in preparation of the manuscript, which was revised by all authors	were involved in preparation of the manuscript, which was revised by all authors	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5474855	28625162	BW	2	generated sequence data	generated sequence data	Performed the experiments	Investigation	YES
5474855	28625162	D-S	2	were involved in preparation of the manuscript, which was revised by all authors	were involved in preparation of the manuscript, which was revised by all authors	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5474855	28625162	FA	2	generated sequence data	generated sequence data	Performed the experiments	Investigation	YES
5474855	28625162	JRB	2	generated sequence data	generated sequence data	Performed the experiments	Investigation	YES
5474855	28625162	KD-S	2	were involved in preparation of the manuscript, which was revised by all authors	were involved in preparation of the manuscript, which was revised by all authors	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5474855	28625162	KDE	2	conceived and designed the tobacco genome study|generated sequence data|were involved in preparation of the manuscript, which was revised by all authors	conceived and designed the tobacco genome study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5474855	28625162	KDE	2	conceived and designed the tobacco genome study|generated sequence data|were involved in preparation of the manuscript, which was revised by all authors	generated sequence data	Performed the experiments	Investigation	YES
5474855	28625162	KDE	2	conceived and designed the tobacco genome study|generated sequence data|were involved in preparation of the manuscript, which was revised by all authors	were involved in preparation of the manuscript, which was revised by all authors	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5474855	28625162	LAM	2	conceived and designed the tobacco genome study	conceived and designed the tobacco genome study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5474855	28625162	MH	2	conceived and designed the tobacco genome study|generated sequence data|were involved in preparation of the manuscript, which was revised by all authors	conceived and designed the tobacco genome study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5474855	28625162	MH	2	conceived and designed the tobacco genome study|generated sequence data|were involved in preparation of the manuscript, which was revised by all authors	generated sequence data	Performed the experiments	Investigation	YES
5474855	28625162	MH	2	conceived and designed the tobacco genome study|generated sequence data|were involved in preparation of the manuscript, which was revised by all authors	were involved in preparation of the manuscript, which was revised by all authors	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5474855	28625162	NF	2	were involved in preparation of the manuscript, which was revised by all authors	were involved in preparation of the manuscript, which was revised by all authors	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5474855	28625162	NF-P	2	conceived and designed the tobacco genome study	conceived and designed the tobacco genome study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5474855	28625162	RH	2	generated sequence data	generated sequence data	Performed the experiments	Investigation	YES
5474855	28625162	RL	2	were involved in preparation of the manuscript, which was revised by all authors	were involved in preparation of the manuscript, which was revised by all authors	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4410941	25915616	A. Katana	PLoS5	Contributed to the interpretation of the results	Contributed to the interpretation of the results	Analyzed the data	Formal analysis	YES
4410941	25915616	A. Kuwawenaruwa	PLoS5	Contributed to the interpretation of the results	Contributed to the interpretation of the results	Analyzed the data	Formal analysis	YES
4410941	25915616	AM	PLoS5	Contributed to the interpretation of the results	Contributed to the interpretation of the results	Analyzed the data	Formal analysis	YES
4410941	25915616	CM	PLoS5	Conceived and designed the experiments|Wrote the paper|Contributed to the interpretation of the results	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4410941	25915616	CM	PLoS5	Conceived and designed the experiments|Wrote the paper|Contributed to the interpretation of the results	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4410941	25915616	CM	PLoS5	Conceived and designed the experiments|Wrote the paper|Contributed to the interpretation of the results	Contributed to the interpretation of the results	Analyzed the data	Formal analysis	YES
4410941	25915616	EM	PLoS5	Contributed to the interpretation of the results	Contributed to the interpretation of the results	Analyzed the data	Formal analysis	YES
4410941	25915616	ES	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Contributed to the interpretation of the results	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4410941	25915616	ES	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Contributed to the interpretation of the results	Analyzed the data	Analyzed the data	Formal analysis	YES
4410941	25915616	ES	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Contributed to the interpretation of the results	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4410941	25915616	ES	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Contributed to the interpretation of the results	Contributed to the interpretation of the results	Analyzed the data	Formal analysis	YES
4410941	25915616	GM-N	PLoS5	Contributed to the interpretation of the results	Contributed to the interpretation of the results	Analyzed the data	Formal analysis	YES
4410941	25915616	JA	PLoS5	Contributed to the interpretation of the results	Contributed to the interpretation of the results	Analyzed the data	Formal analysis	YES
4410941	25915616	KH	PLoS5	Conceived and designed the experiments|Wrote the paper|Contributed to the interpretation of the results	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4410941	25915616	KH	PLoS5	Conceived and designed the experiments|Wrote the paper|Contributed to the interpretation of the results	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4410941	25915616	KH	PLoS5	Conceived and designed the experiments|Wrote the paper|Contributed to the interpretation of the results	Contributed to the interpretation of the results	Analyzed the data	Formal analysis	YES
4410941	25915616	LS	PLoS5	Contributed to the interpretation of the results	Contributed to the interpretation of the results	Analyzed the data	Formal analysis	YES
4410941	25915616	MC	PLoS5	Contributed to the interpretation of the results	Contributed to the interpretation of the results	Analyzed the data	Formal analysis	YES
4410941	25915616	MD	PLoS5	Contributed to the interpretation of the results	Contributed to the interpretation of the results	Analyzed the data	Formal analysis	YES
4410941	25915616	MR	PLoS5	Contributed to the interpretation of the results	Contributed to the interpretation of the results	Analyzed the data	Formal analysis	YES
4410941	25915616	PK	PLoS5	Contributed to the interpretation of the results	Contributed to the interpretation of the results	Analyzed the data	Formal analysis	YES
4410941	25915616	RG	PLoS5	Wrote the paper|Contributed to the interpretation of the results	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4410941	25915616	RG	PLoS5	Wrote the paper|Contributed to the interpretation of the results	Contributed to the interpretation of the results	Analyzed the data	Formal analysis	YES
4410941	25915616	SA	PLoS5	Contributed to the interpretation of the results	Contributed to the interpretation of the results	Analyzed the data	Formal analysis	YES
4410941	25915616	SF	PLoS5	Analyzed the data|Wrote the paper|Contributed to the interpretation of the results	Analyzed the data	Analyzed the data	Formal analysis	YES
4410941	25915616	SF	PLoS5	Analyzed the data|Wrote the paper|Contributed to the interpretation of the results	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4410941	25915616	SF	PLoS5	Analyzed the data|Wrote the paper|Contributed to the interpretation of the results	Contributed to the interpretation of the results	Analyzed the data	Formal analysis	YES
5651034	29089948	All authors	2	have read and approved the final version of the manuscript	have read and approved the final version of the manuscript	-	-	NO
5651034	29089948	BH	2	performed library preparation and sequencing	performed library preparation and sequencing	Performed the experiments	Investigation	YES
5651034	29089948	DK	2	performed library preparation and sequencing	performed library preparation and sequencing	Performed the experiments	Investigation	YES
5651034	29089948	RR	2	performed library preparation and sequencing	performed library preparation and sequencing	Performed the experiments	Investigation	YES
5651034	29089948	RS	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5651034	29089948	SS	2	performed dna extraction, bait development and data analysis|wrote the manuscript	performed dna extraction, bait development and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5651034	29089948	SS	2	performed dna extraction, bait development and data analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4822446	27045000	J.R.	2	was a clinical group leader, managed the measurements in the oslo university hospital, and contributed to the physiological interpretation of the results	was a clinical group leader, managed the measurements in the oslo university hospital, and contributed to the physiological interpretation of the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Supervision	YES
4822446	27045000	P.V.E.Mc.C.	2	helped in the execution and management of the research and editing the manuscript	helped in the execution and management of the research and editing the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4822446	27045000	S.P.	2	analysed the time-frequency properties of the signals and helped define phases within each oscillatory interval	analysed the time-frequency properties of the signals and helped define phases within each oscillatory interval	-	-	NO
4822446	27045000	T.S.	2	analysed the data, contributed to the interpretation and wrote the manuscript	analysed the data, contributed to the interpretation and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
1800345	17327920	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1800345	17327920	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1800345	17327920	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1800345	17327920	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1800345	17327920	CB	PLoS5	Participated in designing the corneal assays and performed them	Participated in designing the corneal assays and performed them	Conceived and designed the experiments|Performed the experiments	Investigation	YES
1800345	17327920	DB	PLoS5	Participated in designing all the metastasis assays and performed them	Participated in designing all the metastasis assays and performed them	Conceived and designed the experiments|Performed the experiments	Investigation	YES
1800345	17327920	DP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1800345	17327920	DP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1800345	17327920	DP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1800345	17327920	DP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1800345	17327920	GM	PLoS5	Participated in designing all bone marrow transplantation and antibody depletion studies and performed the and contributed to the writing of the paper	Participated in designing all bone marrow transplantation and antibody depletion studies and performed the and contributed to the writing of the paper	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
1800345	17327920	SH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1800345	17327920	SH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1800345	17327920	SH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1800345	17327920	SH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1800345	17327920	SH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6202800	30362662	All	2	authors assisted with the writing and revising of the manuscript, provided final approval of the version to be published and agreed to be accountable for all aspects of the work	authors assisted with the writing and revising of the manuscript, provided final approval of the version to be published and agreed to be accountable for all aspects of the work	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6202800	30362662	CO	2	authors assisted with the writing and revising of the manuscript, provided final approval of the version to be published and agreed to be accountable for all aspects of the work	authors assisted with the writing and revising of the manuscript, provided final approval of the version to be published and agreed to be accountable for all aspects of the work	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6202800	30362662	DRB	2	authors assisted with the writing and revising of the manuscript, provided final approval of the version to be published and agreed to be accountable for all aspects of the work	authors assisted with the writing and revising of the manuscript, provided final approval of the version to be published and agreed to be accountable for all aspects of the work	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6202800	30362662	GEG	2	authors assisted with the writing and revising of the manuscript, provided final approval of the version to be published and agreed to be accountable for all aspects of the work	authors assisted with the writing and revising of the manuscript, provided final approval of the version to be published and agreed to be accountable for all aspects of the work	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6202800	30362662	GT	2	authors assisted with the writing and revising of the manuscript, provided final approval of the version to be published and agreed to be accountable for all aspects of the work	authors assisted with the writing and revising of the manuscript, provided final approval of the version to be published and agreed to be accountable for all aspects of the work	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6202800	30362662	IC	2	authors assisted with the writing and revising of the manuscript, provided final approval of the version to be published and agreed to be accountable for all aspects of the work	authors assisted with the writing and revising of the manuscript, provided final approval of the version to be published and agreed to be accountable for all aspects of the work	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6202800	30362662	JJD	2	authors assisted with the writing and revising of the manuscript, provided final approval of the version to be published and agreed to be accountable for all aspects of the work	authors assisted with the writing and revising of the manuscript, provided final approval of the version to be published and agreed to be accountable for all aspects of the work	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6202800	30362662	LMB	2	authors assisted with the writing and revising of the manuscript, provided final approval of the version to be published and agreed to be accountable for all aspects of the work	authors assisted with the writing and revising of the manuscript, provided final approval of the version to be published and agreed to be accountable for all aspects of the work	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6202800	30362662	VAE	2	wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
4422956	25977878	AGMJ	2	helped interpreting the data and in critically revising the manuscript	helped interpreting the data and in critically revising the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4422956	25977878	HMJ	2	synthesized the aminomethylchroman molecules, helped in interpreting the results and in critically revising the manuscript	synthesized the aminomethylchroman molecules, helped in interpreting the results and in critically revising the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
4422956	25977878	JB	2	helped in the design of experiments, the interpretation of the data and in drafting the manuscript	helped in the design of experiments, the interpretation of the data and in drafting the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4422956	25977878	JPvW	2	carried out the molecular signalling experiments, analysed the data, interpreted the results and drafted the manuscript	carried out the molecular signalling experiments, analysed the data, interpreted the results and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4422956	25977878	MCM	2	was responsible for the design of the camp experiments, helped in analysing the data, interpreting the results and critically revising the manuscript	was responsible for the design of the camp experiments, helped in analysing the data, interpreting the results and critically revising the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Review & Editing	YES
4422956	25977878	PHE	2	helped interpreting the data and in critically revising the manuscript	helped interpreting the data and in critically revising the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4410948	25915043	CV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4410948	25915043	CV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4410948	25915043	CV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4410948	25915043	CV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4410948	25915043	CV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4410948	25915043	FS	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4410948	25915043	KZ	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4410948	25915043	KZ	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4410948	25915043	LC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4410948	25915043	LC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4410948	25915043	LC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4410948	25915043	LC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4410948	25915043	LC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4410948	25915043	LV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4410948	25915043	LV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4410948	25915043	LV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4410948	25915043	LV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4410948	25915043	MC	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4410948	25915043	NH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4410948	25915043	PR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4410948	25915043	PR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4410948	25915043	PR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4410948	25915043	SJ	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5477121	28629368	CT	2	designed the experiments, did the data analysis and wrote the paper	designed the experiments, did the data analysis and wrote the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5477121	28629368	EMI	2	helped the data analysis and contributed to manuscript writing	helped the data analysis and contributed to manuscript writing	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5477121	28629368	LLZ	2	helped the data analysis and contributed to manuscript writing	helped the data analysis and contributed to manuscript writing	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5477121	28629368	QLC	2	helped the data analysis and contributed to manuscript writing	helped the data analysis and contributed to manuscript writing	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5477121	28629368	XZ	2	designed the experiments, did the data analysis and wrote the paper	designed the experiments, did the data analysis and wrote the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5651043	29089951	All of the authors	2	reviewed the final version of the manuscript and approved the manuscript for publication	reviewed the final version of the manuscript and approved the manuscript for publication	Wrote the paper	Writing - Review & Editing	YES
5651043	29089951	DL	2	co-wrote the manuscript	co-wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5651043	29089951	JW	2	co-wrote the manuscript	co-wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5651043	29089951	JZ	2	co-wrote the manuscript	co-wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5651043	29089951	LC	2	provided suggestions and revised the manuscript	provided suggestions and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5651043	29089951	QC	2	conceived this work, wrote and revised the manuscript	conceived this work, wrote and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
5651043	29089951	XC	2	provided suggestions and revised the manuscript	provided suggestions and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5651043	29089951	XK	2	provided suggestions and revised the manuscript	provided suggestions and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5651043	29089951	YY	2	provided suggestions and revised the manuscript	provided suggestions and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5651043	29089951	ZR	2	conceived this work, wrote and revised the manuscript	conceived this work, wrote and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
1800346	17327907	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1800346	17327907	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1800346	17327907	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1800346	17327907	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1800346	17327907	EA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1800346	17327907	EA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1800346	17327907	EA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1800346	17327907	SD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1800346	17327907	SD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1800346	17327907	SD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1800346	17327907	SD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4855403	27140973	D.C.	2	contributed equally to the manuscript	contributed equally to the manuscript	-	-	NO
4855403	27140973	J.V.	2	contributed equally to the manuscript	contributed equally to the manuscript	-	-	NO
6207839	30378274	AH	2	performed and analysed drug measurements	performed and analysed drug measurements	Performed the experiments	Investigation	YES
6207839	30378274	CD	2	performed and analysed drug measurements	performed and analysed drug measurements	Performed the experiments	Investigation	YES
6207839	30378274	CEH	2	designed the research study	designed the research study	Conceived and designed the experiments	Methodology	YES
6207839	30378274	CFK	2	designed the research study|wrote the manuscript with contributions and interpretation of findings from all co-authors	designed the research study	Conceived and designed the experiments	Methodology	YES
6207839	30378274	CFK	2	designed the research study|wrote the manuscript with contributions and interpretation of findings from all co-authors	wrote the manuscript with contributions and interpretation of findings from all co-authors	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6207839	30378274	JF	2	performed and analysed drug measurements	performed and analysed drug measurements	Performed the experiments	Investigation	YES
6207839	30378274	LH	2	recruited study participants and collected data and specimens for analysis	recruited study participants and collected data and specimens for analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6207839	30378274	NAP	2	recruited study participants and collected data and specimens for analysis	recruited study participants and collected data and specimens for analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6207839	30378274	REH	2	designed the research study|wrote the manuscript with contributions and interpretation of findings from all co-authors	designed the research study	Conceived and designed the experiments	Methodology	YES
6207839	30378274	REH	2	designed the research study|wrote the manuscript with contributions and interpretation of findings from all co-authors	wrote the manuscript with contributions and interpretation of findings from all co-authors	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6207839	30378274	SH	2	recruited study participants and collected data and specimens for analysis	recruited study participants and collected data and specimens for analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
1800347	17327923	FK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1800347	17327923	FK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1800347	17327923	FK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1800347	17327923	FK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1800347	17327923	FK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1800347	17327923	ML	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1800347	17327923	ML	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1800347	17327923	ML	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5477169	28629321	IJG	2	provided scripts and advice for rna seq data analysis	provided scripts and advice for rna seq data analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources|Software	YES
5477169	28629321	JLM	2	prepared tissue samples for transmission electron microscopy and captured images	prepared tissue samples for transmission electron microscopy and captured images	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
5477169	28629321	KAD	2	conceived and designed the study|completed all other experiments and all of the data analysis, and was the major contributor in writing this manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5477169	28629321	KAD	2	conceived and designed the study|completed all other experiments and all of the data analysis, and was the major contributor in writing this manuscript	completed all other experiments and all of the data analysis, and was the major contributor in writing this manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5477169	28629321	MFB	2	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5477169	28629321	MGB	2	synthesized cdna libraries and prepared samples for sequencing|provided scripts and advice for rna seq data analysis	synthesized cdna libraries and prepared samples for sequencing	Performed the experiments	Investigation	YES
5477169	28629321	MGB	2	synthesized cdna libraries and prepared samples for sequencing|provided scripts and advice for rna seq data analysis	provided scripts and advice for rna seq data analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources|Software	YES
5477169	28629321	TdK	2	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5477169	28629321	WGDF	2	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5651046	29089954	AS	4	The experimental work was done by	The experimental work was done by	Performed the experiments	Investigation	YES
5651046	29089954	JK	4	The germplasm was provided by	The germplasm was provided by	-	-	NO
5651046	29089954	KS	4	The experimental work was done by|The Ms was edited by	The experimental work was done by	Performed the experiments	Investigation	YES
5651046	29089954	KS	4	The experimental work was done by|The Ms was edited by	The Ms was edited by	Wrote the paper	Writing - Review & Editing	YES
5651046	29089954	SK	4	The germplasm was provided by	The germplasm was provided by	-	-	NO
5651046	29089954	SS	4	The germplasm was provided by	The germplasm was provided by	-	-	NO
4410949	25915411	GY	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4410949	25915411	GY	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4410949	25915411	GY	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4410949	25915411	HL	PLoS5	Conceived and designed the experiments|Analyzed the data|Critical revision	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4410949	25915411	HL	PLoS5	Conceived and designed the experiments|Analyzed the data|Critical revision	Analyzed the data	Analyzed the data	Formal analysis	YES
4410949	25915411	HL	PLoS5	Conceived and designed the experiments|Analyzed the data|Critical revision	Critical revision	Wrote the paper	Writing - Review & Editing	YES
4410949	25915411	QL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4410949	25915411	RL	PLoS5	Conceived and designed the experiments|Analyzed the data|Critical revision	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4410949	25915411	RL	PLoS5	Conceived and designed the experiments|Analyzed the data|Critical revision	Analyzed the data	Analyzed the data	Formal analysis	YES
4410949	25915411	RL	PLoS5	Conceived and designed the experiments|Analyzed the data|Critical revision	Critical revision	Wrote the paper	Writing - Review & Editing	YES
4410949	25915411	WW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4410949	25915411	XS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4410949	25915411	YL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4410949	25915411	YL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4410949	25915411	YL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4934412	27536020	G.K.	4	Experiments were designed and conceived by|Data was analyzed by|Lab facilities/reagents/materials/analysis tools provided and contributed by|Manuscript was written by	Experiments were designed and conceived by	Conceived and designed the experiments	Conceptualization|Methodology	YES
4934412	27536020	G.K.	4	Experiments were designed and conceived by|Data was analyzed by|Lab facilities/reagents/materials/analysis tools provided and contributed by|Manuscript was written by	Data was analyzed by	Analyzed the data	Formal analysis	YES
4934412	27536020	G.K.	4	Experiments were designed and conceived by|Data was analyzed by|Lab facilities/reagents/materials/analysis tools provided and contributed by|Manuscript was written by	Lab facilities/reagents/materials/analysis tools provided and contributed by	-	-	NO
4934412	27536020	G.K.	4	Experiments were designed and conceived by|Data was analyzed by|Lab facilities/reagents/materials/analysis tools provided and contributed by|Manuscript was written by	Manuscript was written by	Wrote the paper	Writing - Original Draft	YES
4934412	27536020	S.M.	4	Experiments were designed and conceived by|Experiments were performed by|Data was analyzed by|Manuscript was written by	Experiments were designed and conceived by	Conceived and designed the experiments	Conceptualization|Methodology	YES
4934412	27536020	S.M.	4	Experiments were designed and conceived by|Experiments were performed by|Data was analyzed by|Manuscript was written by	Experiments were performed by	Performed the experiments	Investigation	YES
4934412	27536020	S.M.	4	Experiments were designed and conceived by|Experiments were performed by|Data was analyzed by|Manuscript was written by	Data was analyzed by	Analyzed the data	Formal analysis	YES
4934412	27536020	S.M.	4	Experiments were designed and conceived by|Experiments were performed by|Data was analyzed by|Manuscript was written by	Manuscript was written by	Wrote the paper	Writing - Original Draft	YES
4934412	27536020	S.S.L.	4	Experiments were designed and conceived by|Data was analyzed by|Manuscript was written by	Experiments were designed and conceived by	Conceived and designed the experiments	Conceptualization|Methodology	YES
4934412	27536020	S.S.L.	4	Experiments were designed and conceived by|Data was analyzed by|Manuscript was written by	Data was analyzed by	Analyzed the data	Formal analysis	YES
4934412	27536020	S.S.L.	4	Experiments were designed and conceived by|Data was analyzed by|Manuscript was written by	Manuscript was written by	Wrote the paper	Writing - Original Draft	YES
4934412	27536020	T.K.	4	Experiments were designed and conceived by|Experiments were performed by|Data was analyzed by|Manuscript was written by	Experiments were designed and conceived by	Conceived and designed the experiments	Conceptualization|Methodology	YES
4934412	27536020	T.K.	4	Experiments were designed and conceived by|Experiments were performed by|Data was analyzed by|Manuscript was written by	Experiments were performed by	Performed the experiments	Investigation	YES
4934412	27536020	T.K.	4	Experiments were designed and conceived by|Experiments were performed by|Data was analyzed by|Manuscript was written by	Data was analyzed by	Analyzed the data	Formal analysis	YES
4934412	27536020	T.K.	4	Experiments were designed and conceived by|Experiments were performed by|Data was analyzed by|Manuscript was written by	Manuscript was written by	Wrote the paper	Writing - Original Draft	YES
4934412	27536020	V.S.	4	Experiments were designed and conceived by|Experiments were performed by|Data was analyzed by	Experiments were designed and conceived by	Conceived and designed the experiments	Conceptualization|Methodology	YES
4934412	27536020	V.S.	4	Experiments were designed and conceived by|Experiments were performed by|Data was analyzed by	Experiments were performed by	Performed the experiments	Investigation	YES
4934412	27536020	V.S.	4	Experiments were designed and conceived by|Experiments were performed by|Data was analyzed by	Data was analyzed by	Analyzed the data	Formal analysis	YES
6216177	30394678	BG	2	conceptualized and designed the study, supervised the study, interpreted the data and critically reviewed the manuscript	conceptualized and designed the study, supervised the study, interpreted the data and critically reviewed the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Supervision|Writing - Review & Editing	YES
6216177	30394678	CA	2	collected and interpreted the data, and critically reviewed the manuscript	collected and interpreted the data, and critically reviewed the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
6216177	30394678	CC	2	collected and interpreted the data, and critically reviewed the manuscript	collected and interpreted the data, and critically reviewed the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
6216177	30394678	CY	2	interpreted the data and critically reviewed the manuscript	interpreted the data and critically reviewed the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
6216177	30394678	HP	2	conceptualized and designed the study, collected, statistically analysed and interpreted the data, and drafted and critically reviewed the manuscript	conceptualized and designed the study, collected, statistically analysed and interpreted the data, and drafted and critically reviewed the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
6216177	30394678	MM	2	collected and interpreted the data, and critically reviewed the manuscript	collected and interpreted the data, and critically reviewed the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
6216177	30394678	NG	2	collected and interpreted the data, and critically reviewed the manuscript	collected and interpreted the data, and critically reviewed the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
6216177	30394678	PL	2	interpreted the data and critically reviewed the manuscript	interpreted the data and critically reviewed the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
6216177	30394678	PS	2	collected and interpreted the data, and critically reviewed the manuscript	collected and interpreted the data, and critically reviewed the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
6216177	30394678	SWC	2	interpreted the data and critically reviewed the manuscript	interpreted the data and critically reviewed the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
6216177	30394678	VGV	2	conceptualized and designed the study, supervised the study, interpreted the data and critically reviewed the manuscript	conceptualized and designed the study, supervised the study, interpreted the data and critically reviewed the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Supervision|Writing - Review & Editing	YES
1800348	17327908	AG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1800348	17327908	AG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1800348	17327908	AG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1800348	17327908	CS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1800348	17327908	JN	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1800348	17327908	JN	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1800348	17327908	JN	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1800348	17327908	KA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1800348	17327908	KA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1800348	17327908	KA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1800348	17327908	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1800348	17327908	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1800348	17327908	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1800348	17327908	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1800348	17327908	MM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1800348	17327908	YW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4901248	27242299	S.R.H.	2	with a specific contribution to the description of the modelling strategies	with a specific contribution to the description of the modelling strategies	Performed the experiments	Methodology	YES
4410951	25915630	CJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4410951	25915630	CJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4410951	25915630	CJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4410951	25915630	FG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4410951	25915630	FG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4410951	25915630	FG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4410951	25915630	PF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4410951	25915630	PF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4410951	25915630	PF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4410951	25915630	PF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4410951	25915630	WK	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4410951	25915630	WK	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4410951	25915630	WS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4410951	25915630	WS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4410951	25915630	XK	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4410951	25915630	XL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4410951	25915630	XL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4410951	25915630	XL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4410951	25915630	XL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4410951	25915630	YW	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4410951	25915630	ZW	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5651047	29089956	DL	PLoS52	designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
5651047	29089956	LC	PLoS52	performed the research	performed the research	Performed the experiments	Investigation	YES
5651047	29089956	LG	PLoS52	performed the research	performed the research	Performed the experiments	Investigation	YES
5651047	29089956	RS	PLoS52	performed the research	performed the research	Performed the experiments	Investigation	YES
5651047	29089956	YJ	PLoS52	performed the research|wrote the paper	performed the research	Performed the experiments	Investigation	YES
5651047	29089956	YJ	PLoS52	performed the research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5651047	29089956	YY	PLoS52	performed the research|wrote the paper	performed the research	Performed the experiments	Investigation	YES
5651047	29089956	YY	PLoS52	performed the research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5651047	29089956	YZ	PLoS52	designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
4934413	27536023	R. Shukla	7	editing and finalizing the manuscript	editing and finalizing the manuscript	Wrote the paper	Writing - Review & Editing	YES
4934413	27536023	S. Kumar	7	drafting and finalizing the manuscript and editing the image	drafting and finalizing the manuscript and editing the image	Analyzed the data|Wrote the paper	Visualization|Writing - Original Draft|Writing - Review & Editing	YES
4934413	27536023	V. Holla	7	drafting and finalizing the manuscript and editing the image	drafting and finalizing the manuscript and editing the image	Analyzed the data|Wrote the paper	Visualization|Writing - Original Draft|Writing - Review & Editing	YES
5477377	28629322	GZ	2	was responsible for genotyping work and mapping the qtls	was responsible for genotyping work and mapping the qtls	Performed the experiments	Investigation	YES
5477377	28629322	HN	2	was responsible for experimental design, supervised the research and took the lead role in writing	was responsible for experimental design, supervised the research and took the lead role in writing	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Supervision	YES
5477377	28629322	ML	2	participated in the analysis of phenotypic data and drafting the manuscript	participated in the analysis of phenotypic data and drafting the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5477377	28629322	NL	2	participated in the experimental design, conducted field experiments and wrote the paper	participated in the experimental design, conducted field experiments and wrote the paper	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5477377	28629322	QM	2	helped with data analysis and revised the manuscript	helped with data analysis and revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5477377	28629322	QX	2	was responsible for genotyping work and mapping the qtls	was responsible for genotyping work and mapping the qtls	Performed the experiments	Investigation	YES
5477377	28629322	XH	2	performed phenotypic data of yield-related traits collection	performed phenotypic data of yield-related traits collection	Performed the experiments	Investigation	YES
5477377	28629322	YM	2	helped with data analysis and revised the manuscript	helped with data analysis and revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5477377	28629322	ZT	2	helped with candidate genes analysis	helped with candidate genes analysis	-	-	NO
6240757	30450699	AW	2	designed the study|designed or undertook the analysis|interpreted the data|wrote the first draft of the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
6240757	30450699	AW	2	designed the study|designed or undertook the analysis|interpreted the data|wrote the first draft of the manuscript	designed or undertook the analysis	Conceived and designed the experiments|Performed the experiments	Investigation	YES
6240757	30450699	AW	2	designed the study|designed or undertook the analysis|interpreted the data|wrote the first draft of the manuscript	interpreted the data	Analyzed the data	Formal analysis	YES
6240757	30450699	AW	2	designed the study|designed or undertook the analysis|interpreted the data|wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
6240757	30450699	CC	2	designed the study|oversaw the data management|designed or undertook the analysis|interpreted the data|wrote the first draft of the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
6240757	30450699	CC	2	designed the study|oversaw the data management|designed or undertook the analysis|interpreted the data|wrote the first draft of the manuscript	oversaw the data management	Analyzed the data	Data curation|Supervision	YES
6240757	30450699	CC	2	designed the study|oversaw the data management|designed or undertook the analysis|interpreted the data|wrote the first draft of the manuscript	designed or undertook the analysis	Conceived and designed the experiments|Performed the experiments	Investigation	YES
6240757	30450699	CC	2	designed the study|oversaw the data management|designed or undertook the analysis|interpreted the data|wrote the first draft of the manuscript	interpreted the data	Analyzed the data	Formal analysis	YES
6240757	30450699	CC	2	designed the study|oversaw the data management|designed or undertook the analysis|interpreted the data|wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
6240757	30450699	CM	2	oversaw the data management	oversaw the data management	Analyzed the data	Data curation|Supervision	YES
6240757	30450699	EP	2	interpreted the data	interpreted the data	Analyzed the data	Formal analysis	YES
6240757	30450699	ES	2	interpreted the data	interpreted the data	Analyzed the data	Formal analysis	YES
6240757	30450699	LS	2	interpreted the data	interpreted the data	Analyzed the data	Formal analysis	YES
6240757	30450699	SN	2	designed the study|oversaw the data management|designed or undertook the analysis|interpreted the data	designed the study	Conceived and designed the experiments	Methodology	YES
6240757	30450699	SN	2	designed the study|oversaw the data management|designed or undertook the analysis|interpreted the data	oversaw the data management	Analyzed the data	Data curation|Supervision	YES
6240757	30450699	SN	2	designed the study|oversaw the data management|designed or undertook the analysis|interpreted the data	designed or undertook the analysis	Conceived and designed the experiments|Performed the experiments	Investigation	YES
6240757	30450699	SN	2	designed the study|oversaw the data management|designed or undertook the analysis|interpreted the data	interpreted the data	Analyzed the data	Formal analysis	YES
4901251	27242305	All authors	2	were involved in the initial conception of the experiments	were involved in the initial conception of the experiments	Conceived and designed the experiments	Conceptualization	YES
4901251	27242305	R.J.Y.	2	made a substantial contribution to the design of the experiments, the acquisition of data, and its analysis and interpretation of data|were involved in drafting the article and revising it critically for intellectual content	made a substantial contribution to the design of the experiments, the acquisition of data, and its analysis and interpretation of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Methodology|Resources	YES
4901251	27242305	R.J.Y.	2	made a substantial contribution to the design of the experiments, the acquisition of data, and its analysis and interpretation of data|were involved in drafting the article and revising it critically for intellectual content	were involved in drafting the article and revising it critically for intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4901251	27242305	Z.-L.L.	2	made a substantial contribution to the design of the experiments, the acquisition of data, and its analysis and interpretation of data|were involved in drafting the article and revising it critically for intellectual content	made a substantial contribution to the design of the experiments, the acquisition of data, and its analysis and interpretation of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Methodology|Resources	YES
4901251	27242305	Z.-L.L.	2	made a substantial contribution to the design of the experiments, the acquisition of data, and its analysis and interpretation of data|were involved in drafting the article and revising it critically for intellectual content	were involved in drafting the article and revising it critically for intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4901251	27242305	all authors	2	gave final approval of the version to be published	gave final approval of the version to be published	-	-	NO
4410953	25915853	BXL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4410953	25915853	BXL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4410953	25915853	BXL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4410953	25915853	HZ	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4410953	25915853	JYL	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4410953	25915853	JYL	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4410953	25915853	KJM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4410953	25915853	MH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4410953	25915853	YXF	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4410953	25915853	ZH	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1800349	17330141	AA	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1800349	17330141	AW	PLoS5	Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1800349	17330141	AW	PLoS5	Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1800349	17330141	GC	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1800349	17330141	GD	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1800349	17330141	GD	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1800349	17330141	GZ	PLoS5	Performed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1800349	17330141	GZ	PLoS5	Performed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1800349	17330141	JH	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1800349	17330141	RM	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1800349	17330141	UB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5651048	29089958	PF-M	PLoS52	designed all experiments performed and data analysis|wrote the paper	designed all experiments performed and data analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5651048	29089958	PF-M	PLoS52	designed all experiments performed and data analysis|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5651048	29089958	RAC	PLoS52	designed all experiments performed and data analysis|wrote the paper	designed all experiments performed and data analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5651048	29089958	RAC	PLoS52	designed all experiments performed and data analysis|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5651048	29089958	RDP	PLoS52	designed all experiments performed and data analysis|wrote the paper	designed all experiments performed and data analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5651048	29089958	RDP	PLoS52	designed all experiments performed and data analysis|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5651048	29089958	RS	PLoS52	designed all experiments performed and data analysis|wrote the paper	designed all experiments performed and data analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5651048	29089958	RS	PLoS52	designed all experiments performed and data analysis|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5887965	29675207	All authors	2	contributed to the discussion	contributed to the discussion	-	-	NO
5887965	29675207	G.C.	2	contributed valuable assistance in electrochemical experiments and cell design	contributed valuable assistance in electrochemical experiments and cell design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5887965	29675207	J.J.C.	2	contributed valuable assistance in electrochemical experiments and cell design	contributed valuable assistance in electrochemical experiments and cell design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5887965	29675207	L.C.	2	devised the concept|wrote the manuscript|supervised the overall project	devised the concept	Conceived and designed the experiments	Conceptualization	YES
5887965	29675207	L.C.	2	devised the concept|wrote the manuscript|supervised the overall project	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5887965	29675207	L.C.	2	devised the concept|wrote the manuscript|supervised the overall project	supervised the overall project	-	Supervision	YES
5887965	29675207	N.K.	2	performed all experimental work on the electrochemical screening and hybrid electrolyser cell|wrote the manuscript	performed all experimental work on the electrochemical screening and hybrid electrolyser cell	Performed the experiments	Investigation	YES
5887965	29675207	N.K.	2	performed all experimental work on the electrochemical screening and hybrid electrolyser cell|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4901256	27242291	B.Y.	2	undertook all the experimental work, performed the majority of the data analysis and completed the first draft of this article	undertook all the experimental work, performed the majority of the data analysis and completed the first draft of this article	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4901256	27242291	C.S.	2	contributed critical comments on the draft of the paper	contributed critical comments on the draft of the paper	Wrote the paper	Writing - Original Draft	YES
4901256	27242291	P.J.W.	2	who also provided significant help on the interpretation of data and revised this article critically	who also provided significant help on the interpretation of data and revised this article critically	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
4901256	27242291	R.S.B.	2	proposed many important suggestions	proposed many important suggestions	Conceived and designed the experiments	Conceptualization	YES
4934415	27536021	M.S.	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4934415	27536021	R.M.R.	PLoS52	carried out the experiment and did the analysis and graphs|wrote the paper	carried out the experiment and did the analysis and graphs	Performed the experiments	Investigation	YES
4934415	27536021	R.M.R.	PLoS52	carried out the experiment and did the analysis and graphs|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5477733	28633640	CG	2	provided the funding of the study, participated in conception and design of the study, and agrees to be accountable for all aspects of the study	provided the funding of the study, participated in conception and design of the study, and agrees to be accountable for all aspects of the study	Conceived and designed the experiments	Conceptualization|Funding acquisition|Methodology	YES
5477733	28633640	DG	2	designed and carried out the animal experiment	designed and carried out the animal experiment	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5477733	28633640	HR	2	designed and carried out the animal experiment	designed and carried out the animal experiment	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5477733	28633640	JJ	2	made substantial contribution to conception and design of the experiment, performed statistical analyses, and helped with drafting the manuscript	made substantial contribution to conception and design of the experiment, performed statistical analyses, and helped with drafting the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5477733	28633640	MtP	2	analyzed and interpreted the data, and drafted the manuscript	analyzed and interpreted the data, and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5477733	28633640	QL	2	designed and carried out the animal experiment	designed and carried out the animal experiment	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5477733	28633640	RNA	2	performed and analyzed the real time pcr	performed and analyzed the real time pcr	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5477733	28633640	SZ	2	participated in conception and design of the experiment and analyses of the results, performed statistical analyses, and agrees to be accountable for accuracy and integrity of the data	participated in conception and design of the experiment and analyses of the results, performed statistical analyses, and agrees to be accountable for accuracy and integrity of the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Data curation|Formal analysis|Investigation|Methodology	YES
5477733	28633640	TD	2	was responsible for acquisition of the data and participated in drafting the manuscript	was responsible for acquisition of the data and participated in drafting the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5477733	28633640	XC	2	designed and carried out the animal experiment	designed and carried out the animal experiment	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5477733	28633640	YH	2	designed and carried out the animal experiment	designed and carried out the animal experiment	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5477733	28633640	ZX	2	designed and carried out the animal experiment	designed and carried out the animal experiment	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4410954	25915656	GL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4410954	25915656	GL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4410954	25915656	GL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4410954	25915656	GL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4410954	25915656	GL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4410954	25915656	IC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed software used in analysis	Analyzed the data	Analyzed the data	Formal analysis	YES
4410954	25915656	IC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed software used in analysis	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4410954	25915656	IC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed software used in analysis	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4410954	25915656	IC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed software used in analysis	Designed software used in analysis	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
4410954	25915656	LG	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4410954	25915656	LG	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4410954	25915656	MV	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4410954	25915656	MV	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4410954	25915656	MV	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4410954	25915656	RE	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4410954	25915656	RE	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4410954	25915656	RS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4410954	25915656	RS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1800350	17327924	ML	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1800350	17327924	ML	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1800350	17327924	PH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1800350	17327924	PH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1800350	17327924	PH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1800350	17327924	PH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4920280	27298433	C.E.M.	2	designed the experiments, and revised and edited the manuscript	designed the experiments, and revised and edited the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
4920280	27298433	K.M.B.	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
4920280	27298433	N.S.W.	2	provided materials and revised the manuscript	provided materials and revised the manuscript	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Review & Editing	YES
4920280	27298433	R.J.M.	2	designed and performed experiments, performed the data analysis, and wrote and edited the manuscript	designed and performed experiments, performed the data analysis, and wrote and edited the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
6246945	30460791	AW	2	acquired, analysed or interpreted the data and critically reviewed the manuscript for important intellectual content	acquired, analysed or interpreted the data and critically reviewed the manuscript for important intellectual content	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
6246945	30460791	CC	2	acquired, analysed or interpreted the data and critically reviewed the manuscript for important intellectual content	acquired, analysed or interpreted the data and critically reviewed the manuscript for important intellectual content	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
6246945	30460791	EM	2	acquired, analysed or interpreted the data and critically reviewed the manuscript for important intellectual content	acquired, analysed or interpreted the data and critically reviewed the manuscript for important intellectual content	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
6246945	30460791	JC	2	acquired, analysed or interpreted the data and critically reviewed the manuscript for important intellectual content	acquired, analysed or interpreted the data and critically reviewed the manuscript for important intellectual content	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
6246945	30460791	JG	2	acquired, analysed or interpreted the data and critically reviewed the manuscript for important intellectual content	acquired, analysed or interpreted the data and critically reviewed the manuscript for important intellectual content	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
6246945	30460791	MH	2	acquired, analysed or interpreted the data and critically reviewed the manuscript for important intellectual content	acquired, analysed or interpreted the data and critically reviewed the manuscript for important intellectual content	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
6246945	30460791	MK	2	conceptualized and designed the study|acquired, analysed or interpreted the data and critically reviewed the manuscript for important intellectual content	conceptualized and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6246945	30460791	MK	2	conceptualized and designed the study|acquired, analysed or interpreted the data and critically reviewed the manuscript for important intellectual content	acquired, analysed or interpreted the data and critically reviewed the manuscript for important intellectual content	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
6246945	30460791	NK	2	has had full access to all the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis|conceptualized and designed the study|acquired, analysed or interpreted the data and critically reviewed the manuscript for important intellectual content|drafted the manuscript	has had full access to all the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis	Analyzed the data	Data curation|Formal analysis	YES
6246945	30460791	NK	2	has had full access to all the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis|conceptualized and designed the study|acquired, analysed or interpreted the data and critically reviewed the manuscript for important intellectual content|drafted the manuscript	conceptualized and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6246945	30460791	NK	2	has had full access to all the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis|conceptualized and designed the study|acquired, analysed or interpreted the data and critically reviewed the manuscript for important intellectual content|drafted the manuscript	acquired, analysed or interpreted the data and critically reviewed the manuscript for important intellectual content	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
6246945	30460791	NK	2	has had full access to all the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis|conceptualized and designed the study|acquired, analysed or interpreted the data and critically reviewed the manuscript for important intellectual content|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
6246945	30460791	RN	2	acquired, analysed or interpreted the data and critically reviewed the manuscript for important intellectual content|statistically analysed the data	acquired, analysed or interpreted the data and critically reviewed the manuscript for important intellectual content	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
6246945	30460791	RN	2	acquired, analysed or interpreted the data and critically reviewed the manuscript for important intellectual content|statistically analysed the data	statistically analysed the data	Analyzed the data	Formal analysis	YES
6246945	30460791	SW	2	acquired, analysed or interpreted the data and critically reviewed the manuscript for important intellectual content	acquired, analysed or interpreted the data and critically reviewed the manuscript for important intellectual content	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
6246945	30460791	VLM	2	acquired, analysed or interpreted the data and critically reviewed the manuscript for important intellectual content	acquired, analysed or interpreted the data and critically reviewed the manuscript for important intellectual content	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
3791671	24163636	B. Li	2	contributed equally to this work and are joint first authors	contributed equally to this work and are joint first authors	-	-	NO
3791671	24163636	J. Cheng	2	contributed equally to this work and are joint first authors	contributed equally to this work and are joint first authors	-	-	NO
5651052	29089959	AI	2	supervised the work and revised the manuscript	supervised the work and revised the manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
5651052	29089959	AK	2	performed the experiments, analyzed the data, and wrote the manuscript	performed the experiments, analyzed the data, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5651052	29089959	DL	2	supervised the work and revised the manuscript	supervised the work and revised the manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
5651052	29089959	KL	2	supervised the work and revised the manuscript	supervised the work and revised the manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
5651052	29089959	ZBY	2	designed the research|supervised the work and revised the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
5651052	29089959	ZBY	2	designed the research|supervised the work and revised the manuscript	supervised the work and revised the manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
1800908	17342203	AF	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1800908	17342203	AF	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1800908	17342203	CB	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1800908	17342203	CB	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1800908	17342203	DE	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1800908	17342203	DE	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1800908	17342203	FH	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1800908	17342203	FH	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1800908	17342203	HS	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1800908	17342203	HS	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1800908	17342203	NC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1800908	17342203	NC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1800908	17342203	NC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1800908	17342203	NC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5651053	29089960	CD	2	initiated the research, designed the study and discussed the results	initiated the research, designed the study and discussed the results	Conceived and designed the experiments	Conceptualization|Methodology	YES
5651053	29089960	EJ	2	initiated the research, designed the study and discussed the results|coordinated the analysis of the results and the writing of the manuscript	initiated the research, designed the study and discussed the results	Conceived and designed the experiments	Conceptualization|Methodology	YES
5651053	29089960	EJ	2	initiated the research, designed the study and discussed the results|coordinated the analysis of the results and the writing of the manuscript	coordinated the analysis of the results and the writing of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Project administration|Writing - Original Draft	YES
5651053	29089960	HD	2	performed the protein extractions from purified cell walls and contributed to the analyses of results	performed the protein extractions from purified cell walls and contributed to the analyses of results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5651053	29089960	VH	2	performed the protein extractions from purified cell walls and contributed to the analyses of results	performed the protein extractions from purified cell walls and contributed to the analyses of results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4410955	25915746	JX	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4410955	25915746	LL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4410955	25915746	SP	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4410955	25915746	YH	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4410955	25915746	YT	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4410955	25915746	YW	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5477773	27552923	AY	2	performed evolutionary experiments	performed evolutionary experiments	Performed the experiments	Investigation	YES
5477773	27552923	All authors	2	conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5477773	27552923	NB	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5477773	27552923	ZT	2	performed rna seq experiments and data analysis|wrote the manuscript	performed rna seq experiments and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5477773	27552923	ZT	2	performed rna seq experiments and data analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4938062	27402924	H.Y.	2	revised it critically for important intellectual content	revised it critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4938062	27402924	L.Z.	2	revised it critically for important intellectual content	revised it critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
6250855	30465689	AM	2	reviewed the paper	reviewed the paper	Wrote the paper	Writing - Review & Editing	YES
6250855	30465689	AP	2	designed the research question, extensively reviewed the analyses and the paper	designed the research question, extensively reviewed the analyses and the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Review & Editing	YES
6250855	30465689	All authors	2	have read and approved the final manuscript	have read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6250855	30465689	CD	2	reviewed the paper	reviewed the paper	Wrote the paper	Writing - Review & Editing	YES
6250855	30465689	EF	2	reviewed the paper	reviewed the paper	Wrote the paper	Writing - Review & Editing	YES
6250855	30465689	FC	2	reviewed the paper	reviewed the paper	Wrote the paper	Writing - Review & Editing	YES
6250855	30465689	JD	2	reviewed the paper	reviewed the paper	Wrote the paper	Writing - Review & Editing	YES
6250855	30465689	JRH	2	reviewed the paper	reviewed the paper	Wrote the paper	Writing - Review & Editing	YES
6250855	30465689	LBM	2	performed the analyses and wrote the paper	performed the analyses and wrote the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6250855	30465689	OM	2	reviewed the paper	reviewed the paper	Wrote the paper	Writing - Review & Editing	YES
6250855	30465689	RY	2	reviewed the paper	reviewed the paper	Wrote the paper	Writing - Review & Editing	YES
6250855	30465689	SM	2	reviewed the paper	reviewed the paper	Wrote the paper	Writing - Review & Editing	YES
6250855	30465689	SN	2	reviewed the paper	reviewed the paper	Wrote the paper	Writing - Review & Editing	YES
6250855	30465689	TA	2	reviewed the paper	reviewed the paper	Wrote the paper	Writing - Review & Editing	YES
6250855	30465689	VC	2	designed the research question, extensively reviewed the analyses and the paper	designed the research question, extensively reviewed the analyses and the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Review & Editing	YES
4561303	26380287	Inas Helwa	2	contributed equally to this work	contributed equally to this work	-	-	NO
4561303	26380287	Khaled K. Abu-Amero	2	contributed equally to this work	contributed equally to this work	-	-	NO
1800909	17327906	EC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1800909	17327906	HS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1800909	17327906	HS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1800909	17327906	HS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1800909	17327906	HS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1800909	17327906	HS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1800909	17327906	KS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1800909	17327906	OI	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1800909	17327906	OI	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1800909	17327906	OI	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1800909	17327906	WK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5651077	29089955	GW	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5651077	29089955	JF	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5651077	29089955	JW	PLoS52	designed the research|wrote the article	designed the research	Conceived and designed the experiments	Methodology	YES
5651077	29089955	JW	PLoS52	designed the research|wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
5651077	29089955	YL	PLoS52	designed the research|performed the research|analyzed the data|wrote the article	designed the research	Conceived and designed the experiments	Methodology	YES
5651077	29089955	YL	PLoS52	designed the research|performed the research|analyzed the data|wrote the article	performed the research	Performed the experiments	Investigation	YES
5651077	29089955	YL	PLoS52	designed the research|performed the research|analyzed the data|wrote the article	analyzed the data	Analyzed the data	Formal analysis	YES
5651077	29089955	YL	PLoS52	designed the research|performed the research|analyzed the data|wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
5651077	29089955	YjL	PLoS52	designed the research|analyzed the data|wrote the article	designed the research	Conceived and designed the experiments	Methodology	YES
5651077	29089955	YjL	PLoS52	designed the research|analyzed the data|wrote the article	analyzed the data	Analyzed the data	Formal analysis	YES
5651077	29089955	YjL	PLoS52	designed the research|analyzed the data|wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
5651077	29089955	ZZ	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
4410956	25915601	CS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4410956	25915601	CS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4410956	25915601	CS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4410956	25915601	CS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4410956	25915601	JDL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4410956	25915601	KCW	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4410956	25915601	KCW	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4410956	25915601	MP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4410956	25915601	PJA	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4410956	25915601	THB	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4938075	27402937	Q.Z.	2	helped in revising it critically for important intellectual content and final approval of the version to be published	helped in revising it critically for important intellectual content and final approval of the version to be published	Wrote the paper	Writing - Review & Editing	YES
4938075	27402937	T.M.C.	2	substantially contributed to conception and design, acquisition of data, analysis and interpretation of data and drafting the article	substantially contributed to conception and design, acquisition of data, analysis and interpretation of data and drafting the article	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Resources|Writing - Original Draft	YES
5480177	28637447	CKO	2	performed the data analysis	performed the data analysis	Analyzed the data	Formal analysis	YES
5480177	28637447	DRA	2	wrote the manuscript, and all authors read and approved the final manuscript	wrote the manuscript, and all authors read and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5480177	28637447	FTC	2	designed the experiment	designed the experiment	Conceived and designed the experiments	Methodology	YES
5480177	28637447	HFT	2	performed the data analysis|wrote the manuscript, and all authors read and approved the final manuscript	performed the data analysis	Analyzed the data	Formal analysis	YES
5480177	28637447	HFT	2	performed the data analysis|wrote the manuscript, and all authors read and approved the final manuscript	wrote the manuscript, and all authors read and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5480177	28637447	HK	2	designed the experiment	designed the experiment	Conceived and designed the experiments	Methodology	YES
5480177	28637447	KLK	2	performed the experiment	performed the experiment	Performed the experiments	Investigation	YES
5480177	28637447	KM	2	wrote the manuscript, and all authors read and approved the final manuscript	wrote the manuscript, and all authors read and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5480177	28637447	QBK	2	performed the data analysis	performed the data analysis	Analyzed the data	Formal analysis	YES
5480177	28637447	SM	2	wrote the manuscript, and all authors read and approved the final manuscript	wrote the manuscript, and all authors read and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5480177	28637447	TEKO	2	wrote the manuscript, and all authors read and approved the final manuscript	wrote the manuscript, and all authors read and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5480177	28637447	YCW	2	designed the experiment|performed the experiment|performed the data analysis|wrote the manuscript, and all authors read and approved the final manuscript	designed the experiment	Conceived and designed the experiments	Methodology	YES
5480177	28637447	YCW	2	designed the experiment|performed the experiment|performed the data analysis|wrote the manuscript, and all authors read and approved the final manuscript	performed the experiment	Performed the experiments	Investigation	YES
5480177	28637447	YCW	2	designed the experiment|performed the experiment|performed the data analysis|wrote the manuscript, and all authors read and approved the final manuscript	performed the data analysis	Analyzed the data	Formal analysis	YES
5480177	28637447	YCW	2	designed the experiment|performed the experiment|performed the data analysis|wrote the manuscript, and all authors read and approved the final manuscript	wrote the manuscript, and all authors read and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6253066	30474351	AG	PLoS52	designed the study and data collection tools, and participated in data analysis|conducted the data collection	designed the study and data collection tools, and participated in data analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
6253066	30474351	AG	PLoS52	designed the study and data collection tools, and participated in data analysis|conducted the data collection	conducted the data collection	Performed the experiments	Investigation	YES
6253066	30474351	ALD	PLoS52	analysed the data|drafted the initial manuscript	analysed the data	Analyzed the data	Formal analysis	YES
6253066	30474351	ALD	PLoS52	analysed the data|drafted the initial manuscript	drafted the initial manuscript	Wrote the paper	Writing - Original Draft	YES
6253066	30474351	All authors	PLoS52	contributed to drafting and finalizing the manuscript	contributed to drafting and finalizing the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6253066	30474351	PAN	PLoS52	designed the study and data collection tools, and participated in data analysis|revised the manuscript	designed the study and data collection tools, and participated in data analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
6253066	30474351	PAN	PLoS52	designed the study and data collection tools, and participated in data analysis|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
6253066	30474351	ST	PLoS52	analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
1800910	17342202	AD	PLoS5	Revised the draft	Revised the draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
1800910	17342202	AW	PLoS5	Contributed reagents/materials/analysis tools|Revised the draft	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1800910	17342202	AW	PLoS5	Contributed reagents/materials/analysis tools|Revised the draft	Revised the draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
1800910	17342202	BP	PLoS5	Contributed reagents/materials/analysis tools|Revised the draft	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1800910	17342202	BP	PLoS5	Contributed reagents/materials/analysis tools|Revised the draft	Revised the draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
1800910	17342202	CH	PLoS5	Contributed reagents/materials/analysis tools|Revised the draft	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1800910	17342202	CH	PLoS5	Contributed reagents/materials/analysis tools|Revised the draft	Revised the draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
1800910	17342202	DE	PLoS5	Contributed reagents/materials/analysis tools|Revised the draft	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1800910	17342202	DE	PLoS5	Contributed reagents/materials/analysis tools|Revised the draft	Revised the draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
1800910	17342202	EH	PLoS5	Contributed reagents/materials/analysis tools|Revised the draft	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1800910	17342202	EH	PLoS5	Contributed reagents/materials/analysis tools|Revised the draft	Revised the draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
1800910	17342202	HS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1800910	17342202	HS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1800910	17342202	HS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1800910	17342202	HS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1800910	17342202	IJ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1800910	17342202	PP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1800910	17342202	PP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1800910	17342202	PP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1800910	17342202	RD	PLoS5	Contributed reagents/materials/analysis tools|Revised the draft	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1800910	17342202	RD	PLoS5	Contributed reagents/materials/analysis tools|Revised the draft	Revised the draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
1800910	17342202	SG	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1800910	17342202	SG	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1800910	17342202	SK	PLoS5	Contributed reagents/materials/analysis tools|Revised the draft	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1800910	17342202	SK	PLoS5	Contributed reagents/materials/analysis tools|Revised the draft	Revised the draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
1800910	17342202	SR	PLoS5	Performed the experiments|Revised the draft	Performed the experiments	Performed the experiments	Investigation	YES
1800910	17342202	SR	PLoS5	Performed the experiments|Revised the draft	Revised the draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
1800910	17342202	VM	PLoS5	Contributed reagents/materials/analysis tools|Revised the draft	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1800910	17342202	VM	PLoS5	Contributed reagents/materials/analysis tools|Revised the draft	Revised the draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4943635	27536017	A.G.	7	critical revision of draft and valuable input	critical revision of draft and valuable input	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4943635	27536017	P.P.	7	design of study	design of study	Conceived and designed the experiments	Methodology	YES
4943635	27536017	R.K.	7	data collection, drafting of manuscript, statistical analysis	data collection, drafting of manuscript, statistical analysis	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4943635	27536017	Y.S.	7	data collection, drafting, interpretation of result	data collection, drafting, interpretation of result	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5651081	29089957	All authors	2	contributed to drafting the manuscript and/or helped revise the manuscript	contributed to drafting the manuscript and/or helped revise the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5651081	29089957	JP	2	selected 9k markers for inclusion on the 50k chip and generated data for the chip validation	selected 9k markers for inclusion on the 50k chip and generated data for the chip validation	Performed the experiments	Investigation|Validation	YES
5651081	29089957	LR	2	generated the strategy for inclusion of markers on the chip|carried out the stratification of markers across chromosomes, the comparison of physical vs	generated the strategy for inclusion of markers on the chip	Performed the experiments	Investigation	YES
5651081	29089957	LR	2	generated the strategy for inclusion of markers on the chip|carried out the stratification of markers across chromosomes, the comparison of physical vs	carried out the stratification of markers across chromosomes, the comparison of physical vs	Performed the experiments	Investigation	YES
5651081	29089957	MB	2	carried out the variant calling and downstream analysis of the exome capture data	carried out the variant calling and downstream analysis of the exome capture data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5651081	29089957	MG	2	selected 9k markers for inclusion on the 50k chip and generated data for the chip validation	selected 9k markers for inclusion on the 50k chip and generated data for the chip validation	Performed the experiments	Investigation|Validation	YES
5651081	29089957	PH	2	generated the strategy for inclusion of markers on the chip	generated the strategy for inclusion of markers on the chip	Performed the experiments	Investigation	YES
5651081	29089957	PR	2	carried out the benchmarking of the gatk components	carried out the benchmarking of the gatk components	Performed the experiments	Investigation	YES
5651081	29089957	PS	2	generated the snp marker database and web interface	generated the snp marker database and web interface	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5651081	29089957	RW	2	coordinated and supervised the work	coordinated and supervised the work	-	Project administration|Supervision	YES
5651081	29089957	WT	2	curated the set of lines used for validation	curated the set of lines used for validation	Performed the experiments|Analyzed the data	Data curation|Validation	YES
4561306	26380286	Gang Cao	2	contributed equally to this work	contributed equally to this work	-	-	NO
4561306	26380286	Jue Hu	2	contributed equally to this work	contributed equally to this work	-	-	NO
4410957	25915937	DYF	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4410957	25915937	FW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4410957	25915937	FW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4410957	25915937	FW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4410957	25915937	FW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4410957	25915937	HZT	PLoS5	Contributed reagents/materials/analysis tools|Obtained permission for use experimental field	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4410957	25915937	HZT	PLoS5	Contributed reagents/materials/analysis tools|Obtained permission for use experimental field	Obtained permission for use experimental field	-	-	NO
4410957	25915937	JJZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4410957	25915937	JJZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4410957	25915937	JJZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4410957	25915937	JJZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4410957	25915937	JX	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4410957	25915937	MHX	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4410957	25915937	MX	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4410957	25915937	QPY	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4410957	25915937	SGZ	PLoS5	Contributed reagents/materials/analysis tools|Obtained permission for use experimental field	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4410957	25915937	SGZ	PLoS5	Contributed reagents/materials/analysis tools|Obtained permission for use experimental field	Obtained permission for use experimental field	-	-	NO
4410957	25915937	XJH	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4410957	25915937	YHL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
548148	15656914	BL	2	carried out the software development, sequence analysis, and the design of the study	carried out the software development, sequence analysis, and the design of the study	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Software	YES
548148	15656914	LXZ	2	conceived of the study, performed the statistical analysis, and participated in its coordination	conceived of the study, performed the statistical analysis, and participated in its coordination	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Project administration	YES
548148	15656914	QL	2	carried out the software development, sequence analysis, and the design of the study	carried out the software development, sequence analysis, and the design of the study	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Software	YES
6256843	30480373	AB	2	conceptualised and designed the study, contributed to operational needs and clinical oversight when required and critically reviewed the manuscript	conceptualised and designed the study, contributed to operational needs and clinical oversight when required and critically reviewed the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Supervision|Writing - Review & Editing	YES
6256843	30480373	All	2	approved the final draft	approved the final draft	Wrote the paper	Writing - Original Draft	YES
6256843	30480373	EK	2	conducted the study, cleaned and analysed the data and prepared the manuscript	conducted the study, cleaned and analysed the data and prepared the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Formal analysis|Investigation|Writing - Original Draft	YES
6256843	30480373	JE	2	contributed to data management and analysis and critically reviewed the manuscript	contributed to data management and analysis and critically reviewed the manuscript	Analyzed the data|Wrote the paper	Data curation|Formal analysis|Writing - Review & Editing	YES
6256843	30480373	KS	2	conceptualised and designed the study, contributed to operational needs and clinical oversight when required and critically reviewed the manuscript	conceptualised and designed the study, contributed to operational needs and clinical oversight when required and critically reviewed the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Supervision|Writing - Review & Editing	YES
6256843	30480373	MAD	2	conceptualised and designed the study, contributed to operational needs and clinical oversight when required and critically reviewed the manuscript|contributed to data management and analysis and critically reviewed the manuscript	conceptualised and designed the study, contributed to operational needs and clinical oversight when required and critically reviewed the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Supervision|Writing - Review & Editing	YES
6256843	30480373	MAD	2	conceptualised and designed the study, contributed to operational needs and clinical oversight when required and critically reviewed the manuscript|contributed to data management and analysis and critically reviewed the manuscript	contributed to data management and analysis and critically reviewed the manuscript	Analyzed the data|Wrote the paper	Data curation|Formal analysis|Writing - Review & Editing	YES
6256843	30480373	MK	2	conceptualised and designed the study, contributed to operational needs and clinical oversight when required and critically reviewed the manuscript	conceptualised and designed the study, contributed to operational needs and clinical oversight when required and critically reviewed the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Supervision|Writing - Review & Editing	YES
6256843	30480373	MO	2	conceptualised and designed the study, contributed to operational needs and clinical oversight when required and critically reviewed the manuscript	conceptualised and designed the study, contributed to operational needs and clinical oversight when required and critically reviewed the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Supervision|Writing - Review & Editing	YES
6256843	30480373	VT	2	contributed to data management and analysis and critically reviewed the manuscript	contributed to data management and analysis and critically reviewed the manuscript	Analyzed the data|Wrote the paper	Data curation|Formal analysis|Writing - Review & Editing	YES
5004050	27550767	L.B.	2	contributed to the experimental design, produced the analysis code and wrote the majority of the article	contributed to the experimental design, produced the analysis code and wrote the majority of the article	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Methodology|Software|Writing - Original Draft	YES
5004050	27550767	NEWEx	2	contributed to writing the article	contributed to writing the article	Wrote the paper	Writing - Original Draft	YES
5004050	27550767	R.G.H.	2	led the design of the experiment and contributed to the analysis and writing the article	led the design of the experiment and contributed to the analysis and writing the article	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5004050	27550767	S.L.G.	2	contributed to the design of the experiment and writing the article	contributed to the design of the experiment and writing the article	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
1800911	17342200	AA	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1800911	17342200	AA	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1800911	17342200	AA	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1800911	17342200	AP	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1800911	17342200	AP	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1800911	17342200	BS	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1800911	17342200	BS	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1800911	17342200	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1800911	17342200	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1800911	17342200	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1800911	17342200	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1800911	17342200	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1800911	17342200	JS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1800911	17342200	JS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1800911	17342200	MB	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1800911	17342200	MB	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1800911	17342200	MR	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1800911	17342200	MR	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1800911	17342200	NA	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4410958	25915519	CHY	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4410958	25915519	CYZ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4410958	25915519	FXM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4410958	25915519	GYC	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4410958	25915519	HWD	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4410958	25915519	HWD	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4410958	25915519	HWD	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4410958	25915519	LLS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4410958	25915519	LQZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4410958	25915519	PC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4410958	25915519	PC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4410958	25915519	PC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4410958	25915519	STS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4410958	25915519	WKY	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4410958	25915519	YBZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4410958	25915519	YPT	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4410958	25915519	YPT	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4410958	25915519	YPX	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5651262	29093729	All authors	2	listed have made a substantial, direct and intellectual contribution to the work, and approved it for publication	listed have made a substantial, direct and intellectual contribution to the work, and approved it for publication	-	-	NO
5481885	28645245	APM	PLoS52	contributed materials/analysis tools	contributed materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5481885	28645245	AW	PLoS52	conducted high-throughput sequencing analyses, subsequent statistical analyses, and interpreted the data	conducted high-throughput sequencing analyses, subsequent statistical analyses, and interpreted the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5481885	28645245	All authors	PLoS52	participated in writing and reviewing the manuscript	participated in writing and reviewing the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5481885	28645245	BJC	PLoS52	conducted high-throughput sequencing analyses, subsequent statistical analyses, and interpreted the data	conducted high-throughput sequencing analyses, subsequent statistical analyses, and interpreted the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5481885	28645245	MARM	PLoS52	conceived and designed the experiments|contributed materials/analysis tools	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5481885	28645245	MARM	PLoS52	conceived and designed the experiments|contributed materials/analysis tools	contributed materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5481885	28645245	SL	PLoS52	conceived and designed the experiments|performed the experiments|conducted high-throughput sequencing analyses, subsequent statistical analyses, and interpreted the data	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5481885	28645245	SL	PLoS52	conceived and designed the experiments|performed the experiments|conducted high-throughput sequencing analyses, subsequent statistical analyses, and interpreted the data	performed the experiments	Performed the experiments	Investigation	YES
5481885	28645245	SL	PLoS52	conceived and designed the experiments|performed the experiments|conducted high-throughput sequencing analyses, subsequent statistical analyses, and interpreted the data	conducted high-throughput sequencing analyses, subsequent statistical analyses, and interpreted the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5481885	28645245	THJ	PLoS52	developed plant materials	developed plant materials	Performed the experiments	Investigation	YES
6260921	30485720	All authors	2	reviewed and approved the final version	reviewed and approved the final version	-	-	NO
6260921	30485720	GG	2	conceived the study and designed the modelling analysis	conceived the study and designed the modelling analysis	Conceived and designed the experiments|Performed the experiments	Conceptualization|Methodology	YES
6260921	30485720	JE	2	reviewed the literature to inform the design of the study	reviewed the literature to inform the design of the study	Conceived and designed the experiments	Formal analysis|Methodology	YES
6260921	30485720	SJA	2	conceived the study and designed the modelling analysis|conducted the analyses and wrote the first draft of the manuscript	conceived the study and designed the modelling analysis	Conceived and designed the experiments|Performed the experiments	Conceptualization|Methodology	YES
6260921	30485720	SJA	2	conceived the study and designed the modelling analysis|conducted the analyses and wrote the first draft of the manuscript	conducted the analyses and wrote the first draft of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6260921	30485720	TBH	2	conceived the study and designed the modelling analysis	conceived the study and designed the modelling analysis	Conceived and designed the experiments|Performed the experiments	Conceptualization|Methodology	YES
5004051	27550757	All authors	2	contributed to the final manuscript	contributed to the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5004051	27550757	G.J.M.	2	undertook the lerwick launches, and analysed data	undertook the lerwick launches, and analysed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5004051	27550757	P.D.W.	2	obtained support for the work and developed the impact opportunity to plan the fieldwork	obtained support for the work and developed the impact opportunity to plan the fieldwork	Performed the experiments	Investigation	YES
5004051	27550757	R.G.H.	2	directed this study, wrote software and analysed the data obtained and drafted the manuscript|obtained support for the work and developed the impact opportunity to plan the fieldwork	directed this study, wrote software and analysed the data obtained and drafted the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Software|Supervision|Writing - Original Draft	YES
5004051	27550757	R.G.H.	2	directed this study, wrote software and analysed the data obtained and drafted the manuscript|obtained support for the work and developed the impact opportunity to plan the fieldwork	obtained support for the work and developed the impact opportunity to plan the fieldwork	Performed the experiments	Investigation	YES
4410959	25915761	AD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4410959	25915761	AD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4410959	25915761	AD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4410959	25915761	DB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4410959	25915761	EC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4410959	25915761	ES	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4410959	25915761	ES	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4410959	25915761	ES	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4410959	25915761	HRM	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4410959	25915761	JB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4410959	25915761	JDL	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4410959	25915761	JDL	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4410959	25915761	KC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4410959	25915761	LB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4410959	25915761	MOC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4410959	25915761	MP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4410959	25915761	P-CP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4410959	25915761	RCD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4410959	25915761	RCD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4410959	25915761	RCD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4410959	25915761	SMH	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4410959	25915761	SMH	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1801076	17342201	BK	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1801076	17342201	BK	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1801076	17342201	CM	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1801076	17342201	CM	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1801076	17342201	DC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1801076	17342201	DN	PLoS5	Data interpretation and discussion	Data interpretation and discussion	Analyzed the data	Formal analysis	YES
1801076	17342201	DS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1801076	17342201	DS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1801076	17342201	DS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1801076	17342201	DS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1801076	17342201	EH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1801076	17342201	EH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1801076	17342201	EH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1801076	17342201	JJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1801076	17342201	JJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1801076	17342201	JJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1801076	17342201	JJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1801076	17342201	MM	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1801076	17342201	RB	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1801076	17342201	RB	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1801076	17342201	SS	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1801076	17342201	SS	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1801076	17342201	VM	PLoS5	Data interpretation and discussion	Data interpretation and discussion	Analyzed the data	Formal analysis	YES
3791808	24163611	All the authors	2	revised the paper critically for important intellectual content and gave final approval	revised the paper critically for important intellectual content and gave final approval	Wrote the paper	Writing - Review & Editing	YES
3791808	24163611	Cesare Faldini	2	participated in the design of the study	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
3791808	24163611	Claudio Ripamonti	2	carried out the dxa studies and contributed to its interpretation	carried out the dxa studies and contributed to its interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3791808	24163611	Daniela Cocchi	2	participated in the design of the study and substantially contributed to the statistical analysis and interpretation of data	participated in the design of the study and substantially contributed to the statistical analysis and interpretation of data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
3791808	24163611	Francesca Bruno	2	performed the statistical analysis|contributed equally to this work	performed the statistical analysis	Analyzed the data	Formal analysis	YES
3791808	24163611	Francesca Bruno	2	performed the statistical analysis|contributed equally to this work	contributed equally to this work	-	-	NO
3791808	24163611	Giuliana Nervuti	2	participated in the acquisition of data and coordination of the study	participated in the acquisition of data and coordination of the study	Performed the experiments	Investigation|Project administration	YES
3791808	24163611	Luciano Merlini	2	conceived the study, participated in its design and coordination, and helped to draft the paper	conceived the study, participated in its design and coordination, and helped to draft the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
3791808	24163611	Maria Teresa Miscione	2	have made substantial contribution to acquisition of data|contributed equally to this work	have made substantial contribution to acquisition of data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
3791808	24163611	Maria Teresa Miscione	2	have made substantial contribution to acquisition of data|contributed equally to this work	contributed equally to this work	-	-	NO
3791808	24163611	Massimo Pellegrini	2	participated in the design of the study and carried out the anthropometric evaluations	participated in the design of the study and carried out the anthropometric evaluations	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3791808	24163611	Riccardo Orsini	2	contributed to interpretation of data	contributed to interpretation of data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6263088	30489698	AME	2	revised the manuscript for important intellectual content	revised the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
6263088	30489698	BA	2	acquired the data|revised the manuscript for important intellectual content	acquired the data	Performed the experiments	Investigation	YES
6263088	30489698	BA	2	acquired the data|revised the manuscript for important intellectual content	revised the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
6263088	30489698	LBK	2	revised the manuscript for important intellectual content	revised the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
6263088	30489698	LG	2	revised the manuscript for important intellectual content	revised the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
6263088	30489698	LT	2	provided statistical advice|revised the manuscript for important intellectual content	provided statistical advice	Analyzed the data	Formal analysis	YES
6263088	30489698	LT	2	provided statistical advice|revised the manuscript for important intellectual content	revised the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
6263088	30489698	MVDK	2	conceived the study|performed the statistical analyses and drafted the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
6263088	30489698	MVDK	2	conceived the study|performed the statistical analyses and drafted the manuscript	performed the statistical analyses and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6263088	30489698	PIN	2	acquired the data|revised the manuscript for important intellectual content	acquired the data	Performed the experiments	Investigation	YES
6263088	30489698	PIN	2	acquired the data|revised the manuscript for important intellectual content	revised the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
6263088	30489698	RTL	2	conceived the study|revised the manuscript for important intellectual content	conceived the study	Conceived and designed the experiments	Conceptualization	YES
6263088	30489698	RTL	2	conceived the study|revised the manuscript for important intellectual content	revised the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5651264	29093731	JHA	PLoS52	designed and supervised the study|wrote the manuscript	designed and supervised the study	Conceived and designed the experiments	Methodology|Supervision	YES
5651264	29093731	JHA	PLoS52	designed and supervised the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5651264	29093731	SJ	PLoS52	performed the experiments|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5651264	29093731	SJ	PLoS52	performed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5651264	29093731	SYK	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5004052	27550763	All authors	2	contributed to the final manuscript	contributed to the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5004052	27550763	G.J.M.	2	carried out the balloon launches from the lerwick observatory and performed the data analysis in the manuscript	carried out the balloon launches from the lerwick observatory and performed the data analysis in the manuscript	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5004052	27550763	K.A.N.	2	contributed to discussions over techniques used to interpret the data	contributed to discussions over techniques used to interpret the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5004052	27550763	P.D.W.	2	obtained support for the work and developed the impact opportunity to plan the fieldwork|contributed to discussions over techniques used to interpret the data	obtained support for the work and developed the impact opportunity to plan the fieldwork	Performed the experiments	Investigation	YES
5004052	27550763	P.D.W.	2	obtained support for the work and developed the impact opportunity to plan the fieldwork|contributed to discussions over techniques used to interpret the data	contributed to discussions over techniques used to interpret the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
4410960	25915865	CF	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4410960	25915865	CF	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4410960	25915865	JW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4410960	25915865	JW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4410960	25915865	JW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4410960	25915865	JW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4410960	25915865	ML	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4410960	25915865	ML	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4410960	25915865	ML	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4410960	25915865	ML	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4410960	25915865	NFA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4410960	25915865	NFA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4410960	25915865	NFA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4410960	25915865	NFA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4410960	25915865	NG	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4410960	25915865	PM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4410960	25915865	RMF	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4410960	25915865	SF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4410960	25915865	SF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4410960	25915865	SF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4410960	25915865	SF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4410960	25915865	SF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5481917	28645261	FH	2	prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5481917	28645261	JY	2	prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5481917	28645261	KD	2	participated in manuscript preparation	participated in manuscript preparation	Wrote the paper	Writing - Original Draft	YES
5481917	28645261	TD	2	for ugt gene family, as well as expression analysis of ugt gene family	for ugt gene family, as well as expression analysis of ugt gene family	Performed the experiments	Investigation	YES
5481917	28645261	TK	2	supervised the project and revised the manuscript	supervised the project and revised the manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
5481917	28645261	UGT	2	genes and finished the phylogenetic analysis of ugt gene family	genes and finished the phylogenetic analysis of ugt gene family	Performed the experiments	Investigation	YES
5481917	28645261	WGD	2	for ugt gene family, as well as expression analysis of ugt gene family	for ugt gene family, as well as expression analysis of ugt gene family	Performed the experiments	Investigation	YES
5481917	28645261	ZW	2	supervised the project and revised the manuscript	supervised the project and revised the manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
1803015	17330144	AP	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1803015	17330144	AP	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1803015	17330144	BB	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1803015	17330144	MP	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
6265236	30499224	All authors	2	have contributed to the preparation of the manuscript, read and approved the final draft	have contributed to the preparation of the manuscript, read and approved the final draft	Wrote the paper	Writing - Original Draft	YES
4410989	25915932	AD	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4410989	25915932	AS	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4410989	25915932	GM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4410989	25915932	NS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4410989	25915932	NS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4410989	25915932	OSM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4410989	25915932	OSM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4410989	25915932	OSM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4410989	25915932	OSM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4410989	25915932	OSM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4410989	25915932	US	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5849225	28960139	All authors	2	included in this article fulfill the icmje 2013 criteria of authorship	included in this article fulfill the icmje 2013 criteria of authorship	-	-	NO
5651269	29093720	AK	7	wrote the paper and designed the figures	wrote the paper and designed the figures	Conceived and designed the experiments|Wrote the paper	Visualization|Writing - Original Draft	YES
5651269	29093720	DD	7	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5651269	29093720	DK	7	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5651269	29093720	HK	7	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5651269	29093720	JS	7	wrote the paper and designed the figures	wrote the paper and designed the figures	Conceived and designed the experiments|Wrote the paper	Visualization|Writing - Original Draft	YES
5651269	29093720	KK	7	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5481918	28645248	LK	2	both contributed to the data collection, data generation, bioinformatics, analyses, interpretation, and writing of this manuscript	both contributed to the data collection, data generation, bioinformatics, analyses, interpretation, and writing of this manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5481918	28645248	MDM	2	both contributed to the data collection, data generation, bioinformatics, analyses, interpretation, and writing of this manuscript	both contributed to the data collection, data generation, bioinformatics, analyses, interpretation, and writing of this manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5004053	27550761	A.M.P.	2	drafted and analysed the data for the paper|designed the newex and feedback webforms	drafted and analysed the data for the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5004053	27550761	A.M.P.	2	drafted and analysed the data for the paper|designed the newex and feedback webforms	designed the newex and feedback webforms	Conceived and designed the experiments	-	YES
5004053	27550761	L.B.	2	produced figure 3 and contributed drafting of ssss2b and 3a	produced figure 3 and contributed drafting of ssss2b and 3a	Wrote the paper	Visualization|Writing - Original Draft	YES
5004053	27550761	R.G.H.	2	designed the newex and feedback webforms|revised the final manuscript with contributions from all authors	designed the newex and feedback webforms	Conceived and designed the experiments	-	YES
5004053	27550761	R.G.H.	2	designed the newex and feedback webforms|revised the final manuscript with contributions from all authors	revised the final manuscript with contributions from all authors	Wrote the paper	Writing - Review & Editing	YES
1803016	17327911	CS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1803016	17327911	DG	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1803016	17327911	DG	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1803016	17327911	LP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1803016	17327911	VC	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1803016	17327911	VD	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1803016	17327911	VD	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
6446247	30908114	All authors	PLoS52	contributed to conception, design, and drafting of the article	contributed to conception, design, and drafting of the article	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
6446247	30908114	Nadira Faber	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5651273	29093724	DN	2	designed the experiments and edited the manuscript	designed the experiments and edited the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5651273	29093724	II	2	interpreted the data and edited the manuscript	interpreted the data and edited the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5651273	29093724	JO	2	designed the experiments, produced, and analyzed the gene edited plants and wrote the manuscript	designed the experiments, produced, and analyzed the gene edited plants and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5651273	29093724	NT	2	supervised the design of experiments and analysis of edited plants, wrote and edited the manuscript	supervised the design of experiments and analysis of edited plants, wrote and edited the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
5651273	29093724	RB	2	designed the analysis and interpreted sequencing data, wrote and edited the manuscript	designed the analysis and interpreted sequencing data, wrote and edited the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5651273	29093724	TA	2	interpreted the data and edited the manuscript	interpreted the data and edited the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4410991	25915052	AC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Silico analysis of genes	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4410991	25915052	AC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Silico analysis of genes	Performed the experiments	Performed the experiments	Investigation	YES
4410991	25915052	AC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Silico analysis of genes	Analyzed the data	Analyzed the data	Formal analysis	YES
4410991	25915052	AC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Silico analysis of genes	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4410991	25915052	AC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Silico analysis of genes	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4410991	25915052	AC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Silico analysis of genes	Silico analysis of genes	-	-	NO
4410991	25915052	AK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Silico analysis of genes	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4410991	25915052	AK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Silico analysis of genes	Analyzed the data	Analyzed the data	Formal analysis	YES
4410991	25915052	AK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Silico analysis of genes	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4410991	25915052	AK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Silico analysis of genes	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4410991	25915052	AK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Silico analysis of genes	Silico analysis of genes	-	-	NO
4410991	25915052	RBS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4410991	25915052	RBS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4410991	25915052	RSC	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4410991	25915052	TS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4410991	25915052	TS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4410991	25915052	VJ	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
6275813	30614622	AE	PLoS52	designed the research study	designed the research study	Conceived and designed the experiments	Methodology	YES
6275813	30614622	AHS	PLoS52	designed the research study	designed the research study	Conceived and designed the experiments	Methodology	YES
6275813	30614622	AJ	PLoS52	designed the research study	designed the research study	Conceived and designed the experiments	Methodology	YES
6275813	30614622	All authors	PLoS52	contributed to revising the manuscript and read and approved the final version	contributed to revising the manuscript and read and approved the final version	Wrote the paper	Writing - Review & Editing	YES
6275813	30614622	CY	PLoS52	designed the research study	designed the research study	Conceived and designed the experiments	Methodology	YES
6275813	30614622	GRS	PLoS52	designed the research study	designed the research study	Conceived and designed the experiments	Methodology	YES
6275813	30614622	III	PLoS52	designed the research study	designed the research study	Conceived and designed the experiments	Methodology	YES
6275813	30614622	JP	PLoS52	designed the research study	designed the research study	Conceived and designed the experiments	Methodology	YES
6275813	30614622	K Panayidou	PLoS52	analysed the data|wrote the first draft of the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
6275813	30614622	K Panayidou	PLoS52	analysed the data|wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
6275813	30614622	K Patel	PLoS52	designed the research study	designed the research study	Conceived and designed the experiments	Methodology	YES
6275813	30614622	KWK	PLoS52	designed the research study	designed the research study	Conceived and designed the experiments	Methodology	YES
6275813	30614622	MAD	PLoS52	designed the research study|wrote the first draft of the manuscript	designed the research study	Conceived and designed the experiments	Methodology	YES
6275813	30614622	MAD	PLoS52	designed the research study|wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
6275813	30614622	ME	PLoS52	designed the research study|wrote the first draft of the manuscript	designed the research study	Conceived and designed the experiments	Methodology	YES
6275813	30614622	ME	PLoS52	designed the research study|wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
6275813	30614622	MY	PLoS52	designed the research study	designed the research study	Conceived and designed the experiments	Methodology	YES
6275813	30614622	NA	PLoS52	analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
6275813	30614622	RV	PLoS52	designed the research study	designed the research study	Conceived and designed the experiments	Methodology	YES
6275813	30614622	RVD	PLoS52	designed the research study	designed the research study	Conceived and designed the experiments	Methodology	YES
6275813	30614622	VL	PLoS52	designed the research study	designed the research study	Conceived and designed the experiments	Methodology	YES
5004054	27550759	R.G.H.	2	both designed the study|provided some analysis code, performed the analysis of the nocturnal jet, assisted in the interpretation of the analysis and edited the manuscript	both designed the study	Conceived and designed the experiments	Methodology	YES
5004054	27550759	R.G.H.	2	both designed the study|provided some analysis code, performed the analysis of the nocturnal jet, assisted in the interpretation of the analysis and edited the manuscript	provided some analysis code, performed the analysis of the nocturnal jet, assisted in the interpretation of the analysis and edited the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
5004054	27550759	S.L.G.	2	extracted and analysed the observational and model data and drafted the manuscript|both designed the study	extracted and analysed the observational and model data and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5004054	27550759	S.L.G.	2	extracted and analysed the observational and model data and drafted the manuscript|both designed the study	both designed the study	Conceived and designed the experiments	Methodology	YES
1803017	17327912	DM	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1803017	17327912	FF	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1803017	17327912	FF	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1803017	17327912	GH	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1803017	17327912	GK	PLoS5	Conducted the fieldwork and provided samples	Conducted the fieldwork and provided samples	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
1803017	17327912	JF	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1803017	17327912	JF	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1803017	17327912	JH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1803017	17327912	MS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1803017	17327912	SZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1803017	17327912	TS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5481933	28645249	DS	2	designed the study and drafted the manuscript	designed the study and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5481933	28645249	JL	2	carried out the lab work and analyses for the phylogenetic and transcriptome analyses|designed the study and drafted the manuscript	carried out the lab work and analyses for the phylogenetic and transcriptome analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5481933	28645249	JL	2	carried out the lab work and analyses for the phylogenetic and transcriptome analyses|designed the study and drafted the manuscript	designed the study and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5481933	28645249	PS	2	designed the study and drafted the manuscript	designed the study and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4410995	25915046	NK	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4410995	25915046	NK	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4410995	25915046	NK	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4410995	25915046	SK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4410995	25915046	SK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4410995	25915046	TA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4410995	25915046	TA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4410995	25915046	TA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4410995	25915046	TA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4410995	25915046	TA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4410995	25915046	TN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4410995	25915046	TN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4410995	25915046	TN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4410995	25915046	TN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4410995	25915046	TY	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4410995	25915046	TY	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5651282	29093732	AS	2	conceived the project and supervised the manuscript|drafted the manuscript and contributed to discussions|conducted computer simulations	conceived the project and supervised the manuscript	Conceived and designed the experiments	Conceptualization|Supervision	YES
5651282	29093732	AS	2	conceived the project and supervised the manuscript|drafted the manuscript and contributed to discussions|conducted computer simulations	drafted the manuscript and contributed to discussions	Wrote the paper	Writing - Original Draft	YES
5651282	29093732	AS	2	conceived the project and supervised the manuscript|drafted the manuscript and contributed to discussions|conducted computer simulations	conducted computer simulations	Performed the experiments	Formal analysis|Investigation	YES
5651282	29093732	GH	2	drafted the manuscript and contributed to discussions	drafted the manuscript and contributed to discussions	Wrote the paper	Writing - Original Draft	YES
5651282	29093732	JS	2	drafted the manuscript and contributed to discussions	drafted the manuscript and contributed to discussions	Wrote the paper	Writing - Original Draft	YES
5651282	29093732	ML	2	conceived the project and supervised the manuscript|drafted the manuscript and contributed to discussions|conducted computer simulations	conceived the project and supervised the manuscript	Conceived and designed the experiments	Conceptualization|Supervision	YES
5651282	29093732	ML	2	conceived the project and supervised the manuscript|drafted the manuscript and contributed to discussions|conducted computer simulations	drafted the manuscript and contributed to discussions	Wrote the paper	Writing - Original Draft	YES
5651282	29093732	ML	2	conceived the project and supervised the manuscript|drafted the manuscript and contributed to discussions|conducted computer simulations	conducted computer simulations	Performed the experiments	Formal analysis|Investigation	YES
5651282	29093732	TS	2	drafted the manuscript and contributed to discussions	drafted the manuscript and contributed to discussions	Wrote the paper	Writing - Original Draft	YES
5651282	29093732	YE-K	2	drafted the manuscript and contributed to discussions	drafted the manuscript and contributed to discussions	Wrote the paper	Writing - Original Draft	YES
3791813	24163617	DAccolti	2	contributed equally to this work	contributed equally to this work	-	-	NO
1803018	17342204	AT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1803018	17342204	AT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1803018	17342204	AT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1803018	17342204	MN	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1803018	17342204	MN	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1803018	17342204	MN	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5651362	29093730	AM	7	contributed ideas and text	contributed ideas and text	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5651362	29093730	MR	7	wrote the first draft of the paper	wrote the first draft of the paper	Wrote the paper	Writing - Original Draft	YES
5651362	29093730	RI	7	contributed ideas and text	contributed ideas and text	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4410996	25915539	AK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4410996	25915539	CG	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4410996	25915539	HT	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4410996	25915539	HT	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4410996	25915539	HT	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4410996	25915539	KT	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4410996	25915539	KT	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4410996	25915539	MY	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4410996	25915539	SA	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4410996	25915539	SA	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4410996	25915539	T. Tachi	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4410996	25915539	T. Tachi	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4410996	25915539	T. Tachi	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4410996	25915539	T. Tachi	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4410996	25915539	T. Tachi	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4410996	25915539	T. Tsuchiya	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4410996	25915539	TM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4410996	25915539	TN	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4410996	25915539	TO	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4410996	25915539	YN	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
6280013	30515997	BEN	2	conceived the study|acquired and analysed data for the model|developed the model|interpreted the model results|wrote the first draft of the manuscript|contributed to the writing of the manuscript|read and approved the final manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
6280013	30515997	BEN	2	conceived the study|acquired and analysed data for the model|developed the model|interpreted the model results|wrote the first draft of the manuscript|contributed to the writing of the manuscript|read and approved the final manuscript	acquired and analysed data for the model	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
6280013	30515997	BEN	2	conceived the study|acquired and analysed data for the model|developed the model|interpreted the model results|wrote the first draft of the manuscript|contributed to the writing of the manuscript|read and approved the final manuscript	developed the model	Performed the experiments	Methodology	YES
6280013	30515997	BEN	2	conceived the study|acquired and analysed data for the model|developed the model|interpreted the model results|wrote the first draft of the manuscript|contributed to the writing of the manuscript|read and approved the final manuscript	interpreted the model results	Performed the experiments|Analyzed the data	Formal analysis|Methodology	YES
6280013	30515997	BEN	2	conceived the study|acquired and analysed data for the model|developed the model|interpreted the model results|wrote the first draft of the manuscript|contributed to the writing of the manuscript|read and approved the final manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
6280013	30515997	BEN	2	conceived the study|acquired and analysed data for the model|developed the model|interpreted the model results|wrote the first draft of the manuscript|contributed to the writing of the manuscript|read and approved the final manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
6280013	30515997	BEN	2	conceived the study|acquired and analysed data for the model|developed the model|interpreted the model results|wrote the first draft of the manuscript|contributed to the writing of the manuscript|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6280013	30515997	CM	2	conceived the study|contributed to the writing of the manuscript|read and approved the final manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
6280013	30515997	CM	2	conceived the study|contributed to the writing of the manuscript|read and approved the final manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
6280013	30515997	CM	2	conceived the study|contributed to the writing of the manuscript|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6280013	30515997	DC	2	acquired and analysed data for the model|contributed to the writing of the manuscript|read and approved the final manuscript	acquired and analysed data for the model	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
6280013	30515997	DC	2	acquired and analysed data for the model|contributed to the writing of the manuscript|read and approved the final manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
6280013	30515997	DC	2	acquired and analysed data for the model|contributed to the writing of the manuscript|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6280013	30515997	JK	2	conceived the study|contributed to the writing of the manuscript|read and approved the final manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
6280013	30515997	JK	2	conceived the study|contributed to the writing of the manuscript|read and approved the final manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
6280013	30515997	JK	2	conceived the study|contributed to the writing of the manuscript|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6280013	30515997	LB	2	acquired and analysed data for the model|contributed to the writing of the manuscript|read and approved the final manuscript	acquired and analysed data for the model	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
6280013	30515997	LB	2	acquired and analysed data for the model|contributed to the writing of the manuscript|read and approved the final manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
6280013	30515997	LB	2	acquired and analysed data for the model|contributed to the writing of the manuscript|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6280013	30515997	LS-I	2	acquired and analysed data for the model|contributed to the writing of the manuscript|read and approved the final manuscript	acquired and analysed data for the model	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
6280013	30515997	LS-I	2	acquired and analysed data for the model|contributed to the writing of the manuscript|read and approved the final manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
6280013	30515997	LS-I	2	acquired and analysed data for the model|contributed to the writing of the manuscript|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6280013	30515997	SB	2	wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
6280013	30515997	SJG	2	acquired and analysed data for the model|developed the model|wrote the first draft of the manuscript|contributed to the writing of the manuscript|read and approved the final manuscript	acquired and analysed data for the model	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
6280013	30515997	SJG	2	acquired and analysed data for the model|developed the model|wrote the first draft of the manuscript|contributed to the writing of the manuscript|read and approved the final manuscript	developed the model	Performed the experiments	Methodology	YES
6280013	30515997	SJG	2	acquired and analysed data for the model|developed the model|wrote the first draft of the manuscript|contributed to the writing of the manuscript|read and approved the final manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
6280013	30515997	SJG	2	acquired and analysed data for the model|developed the model|wrote the first draft of the manuscript|contributed to the writing of the manuscript|read and approved the final manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
6280013	30515997	SJG	2	acquired and analysed data for the model|developed the model|wrote the first draft of the manuscript|contributed to the writing of the manuscript|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6280013	30515997	SR	2	interpreted the model results|contributed to the writing of the manuscript|read and approved the final manuscript	interpreted the model results	Performed the experiments|Analyzed the data	Formal analysis|Methodology	YES
6280013	30515997	SR	2	interpreted the model results|contributed to the writing of the manuscript|read and approved the final manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
6280013	30515997	SR	2	interpreted the model results|contributed to the writing of the manuscript|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6280013	30515997	TC	2	acquired and analysed data for the model|developed the model|contributed to the writing of the manuscript|read and approved the final manuscript	acquired and analysed data for the model	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
6280013	30515997	TC	2	acquired and analysed data for the model|developed the model|contributed to the writing of the manuscript|read and approved the final manuscript	developed the model	Performed the experiments	Methodology	YES
6280013	30515997	TC	2	acquired and analysed data for the model|developed the model|contributed to the writing of the manuscript|read and approved the final manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
6280013	30515997	TC	2	acquired and analysed data for the model|developed the model|contributed to the writing of the manuscript|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6280013	30515997	WS	2	acquired and analysed data for the model|contributed to the writing of the manuscript|read and approved the final manuscript	acquired and analysed data for the model	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
6280013	30515997	WS	2	acquired and analysed data for the model|contributed to the writing of the manuscript|read and approved the final manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
6280013	30515997	WS	2	acquired and analysed data for the model|contributed to the writing of the manuscript|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5004055	27550768	E.H.	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5004055	27550768	R.G.H.	2	drafted the manuscript and analysed the data presented	drafted the manuscript and analysed the data presented	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5481934	28645321	AC	PLoS52	gathered samples, prepared hypothalamus and ovary of the goats	gathered samples, prepared hypothalamus and ovary of the goats	Performed the experiments	Investigation	YES
5481934	28645321	AS	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5481934	28645321	AT	PLoS52	gathered samples, prepared hypothalamus and ovary of the goats|conducted the bioinformatics and statistical analysis|participated in improving the manuscript	gathered samples, prepared hypothalamus and ovary of the goats	Performed the experiments	Investigation	YES
5481934	28645321	AT	PLoS52	gathered samples, prepared hypothalamus and ovary of the goats|conducted the bioinformatics and statistical analysis|participated in improving the manuscript	conducted the bioinformatics and statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5481934	28645321	AT	PLoS52	gathered samples, prepared hypothalamus and ovary of the goats|conducted the bioinformatics and statistical analysis|participated in improving the manuscript	participated in improving the manuscript	Wrote the paper	Writing - Review & Editing	YES
5481934	28645321	BC	PLoS52	conceived and designed the experiments|gathered samples, prepared hypothalamus and ovary of the goats|participated in improving the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5481934	28645321	BC	PLoS52	conceived and designed the experiments|gathered samples, prepared hypothalamus and ovary of the goats|participated in improving the manuscript	gathered samples, prepared hypothalamus and ovary of the goats	Performed the experiments	Investigation	YES
5481934	28645321	BC	PLoS52	conceived and designed the experiments|gathered samples, prepared hypothalamus and ovary of the goats|participated in improving the manuscript	participated in improving the manuscript	Wrote the paper	Writing - Review & Editing	YES
5481934	28645321	BL	PLoS52	conducted the bioinformatics and statistical analysis|wrote the manuscript	conducted the bioinformatics and statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5481934	28645321	BL	PLoS52	conducted the bioinformatics and statistical analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5481934	28645321	DG	PLoS52	gathered samples, prepared hypothalamus and ovary of the goats	gathered samples, prepared hypothalamus and ovary of the goats	Performed the experiments	Investigation	YES
5481934	28645321	EC	PLoS52	gathered samples, prepared hypothalamus and ovary of the goats|conducted the bioinformatics and statistical analysis|conducted the experiments|wrote the manuscript	gathered samples, prepared hypothalamus and ovary of the goats	Performed the experiments	Investigation	YES
5481934	28645321	EC	PLoS52	gathered samples, prepared hypothalamus and ovary of the goats|conducted the bioinformatics and statistical analysis|conducted the experiments|wrote the manuscript	conducted the bioinformatics and statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5481934	28645321	EC	PLoS52	gathered samples, prepared hypothalamus and ovary of the goats|conducted the bioinformatics and statistical analysis|conducted the experiments|wrote the manuscript	conducted the experiments	Performed the experiments	Investigation	YES
5481934	28645321	EC	PLoS52	gathered samples, prepared hypothalamus and ovary of the goats|conducted the bioinformatics and statistical analysis|conducted the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5481934	28645321	GP	PLoS52	conceived and designed the experiments|supervised the progress of the project	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5481934	28645321	GP	PLoS52	conceived and designed the experiments|supervised the progress of the project	supervised the progress of the project	-	Supervision	YES
5481934	28645321	JLW	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5481934	28645321	PC	PLoS52	conceived and designed the experiments|supervised the progress of the project|conducted the bioinformatics and statistical analysis|wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5481934	28645321	PC	PLoS52	conceived and designed the experiments|supervised the progress of the project|conducted the bioinformatics and statistical analysis|wrote the manuscript	supervised the progress of the project	-	Supervision	YES
5481934	28645321	PC	PLoS52	conceived and designed the experiments|supervised the progress of the project|conducted the bioinformatics and statistical analysis|wrote the manuscript	conducted the bioinformatics and statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5481934	28645321	PC	PLoS52	conceived and designed the experiments|supervised the progress of the project|conducted the bioinformatics and statistical analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5481934	28645321	PR	PLoS52	gathered samples, prepared hypothalamus and ovary of the goats	gathered samples, prepared hypothalamus and ovary of the goats	Performed the experiments	Investigation	YES
5481934	28645321	SA	PLoS52	gathered samples, prepared hypothalamus and ovary of the goats	gathered samples, prepared hypothalamus and ovary of the goats	Performed the experiments	Investigation	YES
5481934	28645321	SC	PLoS52	gathered samples, prepared hypothalamus and ovary of the goats	gathered samples, prepared hypothalamus and ovary of the goats	Performed the experiments	Investigation	YES
5481934	28645321	SDM	PLoS52	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5481934	28645321	SF	PLoS52	gathered samples, prepared hypothalamus and ovary of the goats|conducted the bioinformatics and statistical analysis|conducted the experiments|wrote the manuscript	gathered samples, prepared hypothalamus and ovary of the goats	Performed the experiments	Investigation	YES
5481934	28645321	SF	PLoS52	gathered samples, prepared hypothalamus and ovary of the goats|conducted the bioinformatics and statistical analysis|conducted the experiments|wrote the manuscript	conducted the bioinformatics and statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5481934	28645321	SF	PLoS52	gathered samples, prepared hypothalamus and ovary of the goats|conducted the bioinformatics and statistical analysis|conducted the experiments|wrote the manuscript	conducted the experiments	Performed the experiments	Investigation	YES
5481934	28645321	SF	PLoS52	gathered samples, prepared hypothalamus and ovary of the goats|conducted the bioinformatics and statistical analysis|conducted the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
1803019	17327913	CA	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1803019	17327913	RT	PLoS5	Discussed results	Discussed results	-	-	NO
1803019	17327913	SP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1803019	17327913	SP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1803019	17327913	SP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1803019	17327913	SP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1803019	17327913	SR	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1803019	17327913	TG	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1803019	17327913	TG	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5651365	29093728	All authors	PLoS52	discussed the data, read, edited the manuscript and approved the final version	discussed the data, read, edited the manuscript and approved the final version	Wrote the paper	Writing - Review & Editing	YES
5651365	29093728	JS	PLoS52	phenotyped and genotyped the population	phenotyped and genotyped the population	Performed the experiments	Investigation	YES
5651365	29093728	LC	PLoS52	phenotyped and genotyped the population|analyzed the data|wrote the main part of the manuscript	phenotyped and genotyped the population	Performed the experiments	Investigation	YES
5651365	29093728	LC	PLoS52	phenotyped and genotyped the population|analyzed the data|wrote the main part of the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5651365	29093728	LC	PLoS52	phenotyped and genotyped the population|analyzed the data|wrote the main part of the manuscript	wrote the main part of the manuscript	Wrote the paper	Writing - Original Draft	YES
5651365	29093728	RS	PLoS52	developed the progenitors of the population|developed the populations|phenotyped and genotyped the population	developed the progenitors of the population	-	-	NO
5651365	29093728	RS	PLoS52	developed the progenitors of the population|developed the populations|phenotyped and genotyped the population	developed the populations	-	-	NO
5651365	29093728	RS	PLoS52	developed the progenitors of the population|developed the populations|phenotyped and genotyped the population	phenotyped and genotyped the population	Performed the experiments	Investigation	YES
5651365	29093728	VG	PLoS52	developed the progenitors of the population|developed the populations|phenotyped and genotyped the population	developed the progenitors of the population	-	-	NO
5651365	29093728	VG	PLoS52	developed the progenitors of the population|developed the populations|phenotyped and genotyped the population	developed the populations	-	-	NO
5651365	29093728	VG	PLoS52	developed the progenitors of the population|developed the populations|phenotyped and genotyped the population	phenotyped and genotyped the population	Performed the experiments	Investigation	YES
5651365	29093728	YH	PLoS52	developed the populations|phenotyped and genotyped the population|analyzed the data	developed the populations	-	-	NO
5651365	29093728	YH	PLoS52	developed the populations|phenotyped and genotyped the population|analyzed the data	phenotyped and genotyped the population	Performed the experiments	Investigation	YES
5651365	29093728	YH	PLoS52	developed the populations|phenotyped and genotyped the population|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5031629	27644981	All authors	PLoS52	contributed to the manuscript	contributed to the manuscript	-	-	NO
5031629	27644981	D.E.H.	PLoS52	performed experiments|analysed the data	performed experiments	Performed the experiments	Investigation	YES
5031629	27644981	D.E.H.	PLoS52	performed experiments|analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
5031629	27644981	D.M.S.	PLoS52	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5031629	27644981	J.L.H.	PLoS52	were responsible for experimental design	were responsible for experimental design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5031629	27644981	J.W.	PLoS52	were responsible for experimental design|performed experiments	were responsible for experimental design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5031629	27644981	J.W.	PLoS52	were responsible for experimental design|performed experiments	performed experiments	Performed the experiments	Investigation	YES
5031629	27644981	R.J.B.	PLoS52	were responsible for experimental design|analysed the data	were responsible for experimental design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5031629	27644981	R.J.B.	PLoS52	were responsible for experimental design|analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
5031629	27644981	S.W.H.	PLoS52	were responsible for experimental design|performed experiments|analysed the data	were responsible for experimental design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5031629	27644981	S.W.H.	PLoS52	were responsible for experimental design|performed experiments|analysed the data	performed experiments	Performed the experiments	Investigation	YES
5031629	27644981	S.W.H.	PLoS52	were responsible for experimental design|performed experiments|analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
548278	15676075	EB	2	tested database and interface	tested database and interface	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
548278	15676075	EC	2	provided supervision and guidance for the project	provided supervision and guidance for the project	-	Supervision	YES
548278	15676075	VG	2	designed and implemented the cascad database	designed and implemented the cascad database	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
4410998	25915521	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4410998	25915521	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4410998	25915521	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4410998	25915521	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4410998	25915521	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4410998	25915521	LB	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4410998	25915521	LB	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4410998	25915521	SU	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4410998	25915521	SU	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4410998	25915521	SU	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4410998	25915521	SU	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6280647	30516346	AG	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
6280647	30516346	BE	2	contributed to data collection	contributed to data collection	Performed the experiments	Investigation	YES
6280647	30516346	BT	2	contributed to data collection	contributed to data collection	Performed the experiments	Investigation	YES
6280647	30516346	CB	2	contributed to data collection|analysed the data and revised the manuscript	contributed to data collection	Performed the experiments	Investigation	YES
6280647	30516346	CB	2	contributed to data collection|analysed the data and revised the manuscript	analysed the data and revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
6280647	30516346	CF	2	designed the study|analysed the data and revised the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
6280647	30516346	CF	2	designed the study|analysed the data and revised the manuscript	analysed the data and revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
6280647	30516346	DT	2	analysed the data and revised the manuscript	analysed the data and revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
6280647	30516346	EC	2	analysed the data and revised the manuscript	analysed the data and revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
6280647	30516346	JH	2	designed the study|contributed to data collection|analysed the data and revised the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
6280647	30516346	JH	2	designed the study|contributed to data collection|analysed the data and revised the manuscript	contributed to data collection	Performed the experiments	Investigation	YES
6280647	30516346	JH	2	designed the study|contributed to data collection|analysed the data and revised the manuscript	analysed the data and revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
6280647	30516346	JO	2	designed the study|contributed to data collection|analysed the data and revised the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
6280647	30516346	JO	2	designed the study|contributed to data collection|analysed the data and revised the manuscript	contributed to data collection	Performed the experiments	Investigation	YES
6280647	30516346	JO	2	designed the study|contributed to data collection|analysed the data and revised the manuscript	analysed the data and revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
6280647	30516346	MC	2	designed the study|contributed to data collection	designed the study	Conceived and designed the experiments	Methodology	YES
6280647	30516346	MC	2	designed the study|contributed to data collection	contributed to data collection	Performed the experiments	Investigation	YES
6280647	30516346	RH	2	analysed the data and revised the manuscript	analysed the data and revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
6280647	30516346	SG	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
6280647	30516346	SW	2	contributed to data collection|analysed the data and revised the manuscript	contributed to data collection	Performed the experiments	Investigation	YES
6280647	30516346	SW	2	contributed to data collection|analysed the data and revised the manuscript	analysed the data and revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
6280647	30516346	TR	2	contributed to data collection|analysed the data and revised the manuscript	contributed to data collection	Performed the experiments	Investigation	YES
6280647	30516346	TR	2	contributed to data collection|analysed the data and revised the manuscript	analysed the data and revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
1803020	17342205	Tv Ad	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1803020	17342205	Tv Ad	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
548281	15667661	AMF	2	helped with experimental design and manuscript preparation	helped with experimental design and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
548281	15667661	YZ	2	did the experimental work	did the experimental work	Performed the experiments	Investigation	YES
4410999	25915854	A. Hemp	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4410999	25915854	A. Hemp	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4410999	25915854	A. Huth	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4410999	25915854	A. Huth	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4410999	25915854	A. Huth	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4410999	25915854	AE	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4410999	25915854	AE	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4410999	25915854	DSC	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4410999	25915854	DSC	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4410999	25915854	GR	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4410999	25915854	GR	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4410999	25915854	MF	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4410999	25915854	MK	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4410999	25915854	RF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4410999	25915854	RF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4410999	25915854	RF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4410999	25915854	RF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4410999	25915854	RF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4410999	25915854	SP	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4410999	25915854	SP	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6282942	30601598	AMO	2	were responsible for data collection	were responsible for data collection	Performed the experiments	Investigation	YES
6282942	30601598	All authors	2	critically reviewed and approved the final version of the manuscript	critically reviewed and approved the final version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
6282942	30601598	DC	2	conceived and designed this analysis|were responsible for data collection|contributed to data analysis and interpretation|conducted the literature search, wrote the manuscript and generated figures	conceived and designed this analysis	Conceived and designed the experiments	Conceptualization	YES
6282942	30601598	DC	2	conceived and designed this analysis|were responsible for data collection|contributed to data analysis and interpretation|conducted the literature search, wrote the manuscript and generated figures	were responsible for data collection	Performed the experiments	Investigation	YES
6282942	30601598	DC	2	conceived and designed this analysis|were responsible for data collection|contributed to data analysis and interpretation|conducted the literature search, wrote the manuscript and generated figures	contributed to data analysis and interpretation	Analyzed the data	Formal analysis	YES
6282942	30601598	DC	2	conceived and designed this analysis|were responsible for data collection|contributed to data analysis and interpretation|conducted the literature search, wrote the manuscript and generated figures	conducted the literature search, wrote the manuscript and generated figures	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Visualization|Writing - Original Draft	YES
6282942	30601598	DJC	2	conceived, designed, implemented and managed the rv254/search 010 study protocol	conceived, designed, implemented and managed the rv254/search 010 study protocol	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology|Project administration	YES
6282942	30601598	EB	2	contributed to data analysis and interpretation	contributed to data analysis and interpretation	Analyzed the data	Formal analysis	YES
6282942	30601598	EK	2	conceived, designed, implemented and managed the rv254/search 010 study protocol	conceived, designed, implemented and managed the rv254/search 010 study protocol	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology|Project administration	YES
6282942	30601598	ESB	2	were responsible for data collection|contributed to data analysis and interpretation	were responsible for data collection	Performed the experiments	Investigation	YES
6282942	30601598	ESB	2	were responsible for data collection|contributed to data analysis and interpretation	contributed to data analysis and interpretation	Analyzed the data	Formal analysis	YES
6282942	30601598	GK	2	contributed to data analysis and interpretation	contributed to data analysis and interpretation	Analyzed the data	Formal analysis	YES
6282942	30601598	JA	2	conceived, designed, implemented and managed the rv254/search 010 study protocol	conceived, designed, implemented and managed the rv254/search 010 study protocol	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology|Project administration	YES
6282942	30601598	JHK	2	conceived, designed, implemented and managed the rv254/search 010 study protocol	conceived, designed, implemented and managed the rv254/search 010 study protocol	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology|Project administration	YES
6282942	30601598	JLE	2	conceived, designed, implemented and managed the rv254/search 010 study protocol	conceived, designed, implemented and managed the rv254/search 010 study protocol	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology|Project administration	YES
6282942	30601598	MB	2	were responsible for data collection	were responsible for data collection	Performed the experiments	Investigation	YES
6282942	30601598	MDS	2	conceived, designed, implemented and managed the rv254/search 010 study protocol	conceived, designed, implemented and managed the rv254/search 010 study protocol	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology|Project administration	YES
6282942	30601598	MLR	2	conceived, designed, implemented and managed the rv254/search 010 study protocol	conceived, designed, implemented and managed the rv254/search 010 study protocol	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology|Project administration	YES
6282942	30601598	NC	2	conceived, designed, implemented and managed the rv254/search 010 study protocol	conceived, designed, implemented and managed the rv254/search 010 study protocol	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology|Project administration	YES
6282942	30601598	NLM	2	conceived, designed, implemented and managed the rv254/search 010 study protocol	conceived, designed, implemented and managed the rv254/search 010 study protocol	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology|Project administration	YES
6282942	30601598	NP	2	conceived, designed, implemented and managed the rv254/search 010 study protocol	conceived, designed, implemented and managed the rv254/search 010 study protocol	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology|Project administration	YES
6282942	30601598	PPham	2	provided bioinformatics support|contributed to data analysis and interpretation	provided bioinformatics support	-	Formal analysis	YES
6282942	30601598	PPham	2	provided bioinformatics support|contributed to data analysis and interpretation	contributed to data analysis and interpretation	Analyzed the data	Formal analysis	YES
6282942	30601598	PPhanuphak	2	conceived, designed, implemented and managed the rv254/search 010 study protocol	conceived, designed, implemented and managed the rv254/search 010 study protocol	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology|Project administration	YES
6282942	30601598	RJO	2	conceived, designed, implemented and managed the rv254/search 010 study protocol	conceived, designed, implemented and managed the rv254/search 010 study protocol	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology|Project administration	YES
6282942	30601598	RS	2	were responsible for data collection	were responsible for data collection	Performed the experiments	Investigation	YES
6282942	30601598	SP	2	provided bioinformatics support	provided bioinformatics support	-	Formal analysis	YES
6282942	30601598	ST	2	conceived and designed this analysis|were responsible for data collection|contributed to data analysis and interpretation	conceived and designed this analysis	Conceived and designed the experiments	Conceptualization	YES
6282942	30601598	ST	2	conceived and designed this analysis|were responsible for data collection|contributed to data analysis and interpretation	were responsible for data collection	Performed the experiments	Investigation	YES
6282942	30601598	ST	2	conceived and designed this analysis|were responsible for data collection|contributed to data analysis and interpretation	contributed to data analysis and interpretation	Analyzed the data	Formal analysis	YES
6282942	30601598	WR	2	were responsible for data collection	were responsible for data collection	Performed the experiments	Investigation	YES
5651519	29093727	All authors	2	made a substantial, direct and intellectual contribution to the work	made a substantial, direct and intellectual contribution to the work	-	-	NO
5651519	29093727	ZH	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
548301	15656902	AAZ	2	participated in discussions, suggested the assignment of genes to functional groups and gave textual advice	participated in discussions, suggested the assignment of genes to functional groups and gave textual advice	-	-	NO
548301	15656902	AL	2	participated in discussions and gave textual advice	participated in discussions and gave textual advice	-	-	NO
548301	15656902	CGCW	2	performed experiments, developed and analyzed functional groups of genes and participated in discussions	performed experiments, developed and analyzed functional groups of genes and participated in discussions	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
548301	15656902	HV	2	participated in discussions and gave textual advice	participated in discussions and gave textual advice	-	-	NO
548301	15656902	JW	2	participated in discussions	participated in discussions	-	-	NO
548301	15656902	LHFM	2	participated in discussions	participated in discussions	-	-	NO
548301	15656902	MB	2	performed experiments, developed and analyzed functional groups of genes and prepared the manuscript	performed experiments, developed and analyzed functional groups of genes and prepared the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
548301	15656902	PS	2	performed microarray normalization and data analysis	performed microarray normalization and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
1803021	17327914	AW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1803021	17327914	GF	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1803021	17327914	GF	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1803021	17327914	JI	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1803021	17327914	JI	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1803021	17327914	JI	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1803021	17327914	MC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1803021	17327914	NB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1803021	17327914	NB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1803021	17327914	NB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1803021	17327914	SL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1803021	17327914	SL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1803021	17327914	SL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1803021	17327914	SL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5031638	27644975	C.M.O.	2	conceived the topic and content for this review, wrote and edited the manuscript and approved the final version	conceived the topic and content for this review, wrote and edited the manuscript and approved the final version	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
5031638	27644975	R.I.V.	2	conceived the topic and content for this review, wrote and edited the manuscript and approved the final version	conceived the topic and content for this review, wrote and edited the manuscript and approved the final version	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
5031638	27644975	T.K.	2	conceived the topic and content for this review, wrote and edited the manuscript and approved the final version	conceived the topic and content for this review, wrote and edited the manuscript and approved the final version	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
4411002	25915946	AG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411002	25915946	AS	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411002	25915946	AS	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411002	25915946	CB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411002	25915946	CS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411002	25915946	CS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411002	25915946	CS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411002	25915946	DCL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411002	25915946	DV	PLoS5	Performed genetic counselling to families of affected individuals	Performed genetic counselling to families of affected individuals	Performed the experiments	Investigation	YES
4411002	25915946	FB	PLoS5	Provided clinical data and performed biopsies from patients	Provided clinical data and performed biopsies from patients	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4411002	25915946	FCS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411002	25915946	GF	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411002	25915946	LC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411002	25915946	MC	PLoS5	Provided clinical data and performed biopsies from patients	Provided clinical data and performed biopsies from patients	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4411002	25915946	MP	PLoS5	Performed genetic counselling to families of affected individuals	Performed genetic counselling to families of affected individuals	Performed the experiments	Investigation	YES
4411002	25915946	NL	PLoS5	Provided clinical data and performed biopsies from patients	Provided clinical data and performed biopsies from patients	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4411002	25915946	NR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411002	25915946	NR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411002	25915946	NR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411002	25915946	PL	PLoS5	Performed genetic counselling to families of affected individuals	Performed genetic counselling to families of affected individuals	Performed the experiments	Investigation	YES
4411002	25915946	RB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411002	25915946	RT	PLoS5	Wrote the paper|Provided clinical data and performed biopsies from patients	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411002	25915946	RT	PLoS5	Wrote the paper|Provided clinical data and performed biopsies from patients	Provided clinical data and performed biopsies from patients	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4411002	25915946	VG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5651524	29093721	ACG	2	were responsible for sample preparation, phenotyping, dna extraction and/or compilation of passport information	were responsible for sample preparation, phenotyping, dna extraction and/or compilation of passport information	Performed the experiments	Investigation	YES
5651524	29093721	AGh	2	provided valuable suggestions on the paper	provided valuable suggestions on the paper	-	-	NO
5651524	29093721	AGo	2	were responsible for sample preparation, phenotyping, dna extraction and/or compilation of passport information	were responsible for sample preparation, phenotyping, dna extraction and/or compilation of passport information	Performed the experiments	Investigation	YES
5651524	29093721	All authors	2	read and approved the paper	read and approved the paper	-	-	NO
5651524	29093721	DDT	2	were responsible for sample preparation, phenotyping, dna extraction and/or compilation of passport information	were responsible for sample preparation, phenotyping, dna extraction and/or compilation of passport information	Performed the experiments	Investigation	YES
5651524	29093721	KS	2	analyzed the data and wrote most part of the paper	analyzed the data and wrote most part of the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5651524	29093721	MLW	2	contributed to and edited the paper	contributed to and edited the paper	Wrote the paper	Writing - Review & Editing	YES
5651524	29093721	MNN	2	conceived, designed, and supervised the experiments, secured funding, and partly drafted the paper	conceived, designed, and supervised the experiments, secured funding, and partly drafted the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Funding acquisition|Methodology|Supervision|Writing - Original Draft	YES
5651524	29093721	MSi	2	provided valuable suggestions on the paper	provided valuable suggestions on the paper	-	-	NO
5651524	29093721	MSo	2	provided valuable suggestions on the paper	provided valuable suggestions on the paper	-	-	NO
5651524	29093721	SBK	2	were responsible for sample preparation, phenotyping, dna extraction and/or compilation of passport information	were responsible for sample preparation, phenotyping, dna extraction and/or compilation of passport information	Performed the experiments	Investigation	YES
5651524	29093721	XP	2	contributed to data analysis to create core and mini-core collection	contributed to data analysis to create core and mini-core collection	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5031647	27644983	All authors	2	gave final approval for publication	gave final approval for publication	-	-	NO
5031647	27644983	K.A.C.	2	carried out the laboratory work, participated in data analysis, participated in the design of the study and drafted the manuscript	carried out the laboratory work, participated in data analysis, participated in the design of the study and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5031647	27644983	R.P.E.	2	conceived of the study, designed the study, coordinated the study, participated in data analysis and helped draft the manuscript	conceived of the study, designed the study, coordinated the study, participated in data analysis and helped draft the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Project administration|Writing - Original Draft	YES
5031647	27644983	S.I.	2	participated in data analysis and helped draft the manuscript	participated in data analysis and helped draft the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
1803022	17342206	LM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1803022	17342206	LM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1803022	17342206	LM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1803022	17342206	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1803022	17342206	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1803022	17342206	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1803022	17342206	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1803022	17342206	MW	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1803022	17342206	MW	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1803022	17342206	MW	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1803022	17342206	WM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1803022	17342206	WM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1803022	17342206	WM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1803022	17342206	WM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4561874	26380292	Chih-Yen Hsiao	2	contributed equally to this work	contributed equally to this work	-	-	NO
4561874	26380292	Huang-Yu Yang	2	contributed equally to this work	contributed equally to this work	-	-	NO
5483258	28646875	CK	2	contributed equally to this work	contributed equally to this work	-	-	NO
5483258	28646875	HH	2	contributed equally to this work	contributed equally to this work	-	-	NO
5483258	28646875	HK	2	contributed equally to this work	contributed equally to this work	-	-	NO
4411004	25915039	AW	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411004	25915039	DB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411004	25915039	DB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411004	25915039	DB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411004	25915039	FW	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411004	25915039	JF	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411004	25915039	JF	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411004	25915039	KH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411004	25915039	KH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411004	25915039	PW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411004	25915039	PW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411004	25915039	PW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411004	25915039	PW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411004	25915039	PW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5052728	27698038	D.G.-C.	2	contributed to the design|analysed and interpreted the data	contributed to the design	Conceived and designed the experiments	-	YES
5052728	27698038	D.G.-C.	2	contributed to the design|analysed and interpreted the data	analysed and interpreted the data	Analyzed the data	Formal analysis	YES
5052728	27698038	H.Z.	2	analysed and interpreted the data	analysed and interpreted the data	Analyzed the data	Formal analysis	YES
5052728	27698038	J.T.	2	designed and conceptualized the paper|analysed and interpreted the data|drafted the article	designed and conceptualized the paper	Conceived and designed the experiments	Conceptualization	YES
5052728	27698038	J.T.	2	designed and conceptualized the paper|analysed and interpreted the data|drafted the article	analysed and interpreted the data	Analyzed the data	Formal analysis	YES
5052728	27698038	J.T.	2	designed and conceptualized the paper|analysed and interpreted the data|drafted the article	drafted the article	Wrote the paper	Writing - Original Draft	YES
5052728	27698038	all authors	2	revised and approved the version to be published	revised and approved the version to be published	Wrote the paper	Writing - Review & Editing	YES
6287094	30649834	BEP	2	contributed to study selection, data collection and manuscript revisions	contributed to study selection, data collection and manuscript revisions	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Resources|Writing - Review & Editing	YES
6287094	30649834	EKS	2	contributed to study selection, data collection, data management and manuscript revisions	contributed to study selection, data collection, data management and manuscript revisions	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Data curation|Investigation|Resources|Writing - Review & Editing	YES
6287094	30649834	HF	2	contributed to study selection, data collection, data management, creation of tables and manuscript revisions	contributed to study selection, data collection, data management, creation of tables and manuscript revisions	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Data curation|Investigation|Resources|Writing - Review & Editing	YES
6287094	30649834	JGC	2	was responsible for study design, oversight, study selection, data collection, data management, preliminary data analyses, interpretation of results, creation of tables and figures, and manuscript preparation	was responsible for study design, oversight, study selection, data collection, data management, preliminary data analyses, interpretation of results, creation of tables and figures, and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Formal analysis|Investigation|Methodology|Supervision|Visualization|Writing - Original Draft	YES
6287094	30649834	KC	2	contributed to data management and manuscript revisions	contributed to data management and manuscript revisions	Analyzed the data|Wrote the paper	Data curation|Writing - Review & Editing	YES
6287094	30649834	KR	2	contributed to study selection, data collection and manuscript revisions	contributed to study selection, data collection and manuscript revisions	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Resources|Writing - Review & Editing	YES
6287094	30649834	SHV	2	was responsible for study design, oversight, study selection, data collection and manuscript revisions	was responsible for study design, oversight, study selection, data collection and manuscript revisions	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Supervision|Writing - Review & Editing	YES
6287094	30649834	YL	2	was responsible for the analytic plan, statistical analyses, interpretation of results, creation of tables and figures and manuscript preparation	was responsible for the analytic plan, statistical analyses, interpretation of results, creation of tables and figures and manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Visualization|Writing - Original Draft	YES
5651529	29093726	AC	2	has also helped in writing the manuscript	has also helped in writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5651529	29093726	AD	2	has downloaded literature and written the manuscript and finally edited it	has downloaded literature and written the manuscript and finally edited it	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5651529	29093726	NA	2	has given the idea of contents	has given the idea of contents	Conceived and designed the experiments	Conceptualization	YES
5651529	29093726	PK	2	has assisted in downloading the material for the manuscript	has assisted in downloading the material for the manuscript	-	-	NO
4411005	25915939	DT	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411005	25915939	HK	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411005	25915939	JH	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4411005	25915939	MHO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411005	25915939	MHO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411005	25915939	MHO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411005	25915939	MHO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411005	25915939	YS	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1803023	17327921	GS	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1803023	17327921	GZ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1803023	17327921	GZ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1803023	17327921	GZ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1803023	17327921	KC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1803023	17327921	KV	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5052730	27698036	A.G.H.	2	conceived the research and wrote the first version of the manuscript	conceived the research and wrote the first version of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5052730	27698036	A.S.	2	contributed to the research on the isr and the whole-body models, and drafted and revised that part of the manuscript and created figure 2	contributed to the research on the isr and the whole-body models, and drafted and revised that part of the manuscript and created figure 2	Performed the experiments|Wrote the paper	Methodology|Visualization|Writing - Original Draft|Writing - Review & Editing	YES
5052730	27698036	All authors	2	contributed to the conception of the concept of the virtual artery and revised those sections of the manuscript	contributed to the conception of the concept of the virtual artery and revised those sections of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5052730	27698036	B.v.R.	2	contributed to the cell-based blood flow models, and drafted and revised the part on the cell-based models	contributed to the cell-based blood flow models, and drafted and revised the part on the cell-based models	Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5052730	27698036	E.L.	2	contributed to the cell-based blood flow models, and drafted and revised the part on the cell-based models	contributed to the cell-based blood flow models, and drafted and revised the part on the cell-based models	Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5052730	27698036	G.Z.	2	contributed to the cell-based blood flow models, and drafted and revised the part on the cell-based models	contributed to the cell-based blood flow models, and drafted and revised the part on the cell-based models	Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5052730	27698036	L.M.	2	contributed to the cell-based blood flow models, and drafted and revised the part on the cell-based models	contributed to the cell-based blood flow models, and drafted and revised the part on the cell-based models	Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5052730	27698036	N.M.	2	contributed to the research on the isr and the whole-body models, and drafted and revised that part of the manuscript and created figure 2	contributed to the research on the isr and the whole-body models, and drafted and revised that part of the manuscript and created figure 2	Performed the experiments|Wrote the paper	Methodology|Visualization|Writing - Original Draft|Writing - Review & Editing	YES
5052730	27698036	P.Z.	2	contributed to the research on the isr and the whole-body models, and drafted and revised that part of the manuscript and created figure 2	contributed to the research on the isr and the whole-body models, and drafted and revised that part of the manuscript and created figure 2	Performed the experiments|Wrote the paper	Methodology|Visualization|Writing - Original Draft|Writing - Review & Editing	YES
5483264	28646867	All	2	authors reviewed and approved the final manuscript	authors reviewed and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5483264	28646867	CKT	2	conceived and designed this project|authors reviewed and approved the final manuscript	conceived and designed this project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5483264	28646867	CKT	2	conceived and designed this project|authors reviewed and approved the final manuscript	authors reviewed and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5483264	28646867	DJN	2	conceived and designed this project|participated in data acquisition|authors reviewed and approved the final manuscript	conceived and designed this project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5483264	28646867	DJN	2	conceived and designed this project|participated in data acquisition|authors reviewed and approved the final manuscript	participated in data acquisition	Performed the experiments	Investigation	YES
5483264	28646867	DJN	2	conceived and designed this project|participated in data acquisition|authors reviewed and approved the final manuscript	authors reviewed and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5483264	28646867	HL	2	conceived and designed this project|participated in data acquisition	conceived and designed this project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5483264	28646867	HL	2	conceived and designed this project|participated in data acquisition	participated in data acquisition	Performed the experiments	Investigation	YES
5483264	28646867	JCMD	2	conceived and designed this project|authors reviewed and approved the final manuscript	conceived and designed this project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5483264	28646867	JCMD	2	conceived and designed this project|authors reviewed and approved the final manuscript	authors reviewed and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5483264	28646867	TPLS	2	conceived and designed this project|participated in data acquisition|authors reviewed and approved the final manuscript	conceived and designed this project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5483264	28646867	TPLS	2	conceived and designed this project|participated in data acquisition|authors reviewed and approved the final manuscript	participated in data acquisition	Performed the experiments	Investigation	YES
5483264	28646867	TPLS	2	conceived and designed this project|participated in data acquisition|authors reviewed and approved the final manuscript	authors reviewed and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5651625	29093722	HD	2	helped in the analysis of the results and editing the manuscript	helped in the analysis of the results and editing the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5651625	29093722	MS	2	designed and carried out the experiments, collected, and analyzed the results, and wrote the manuscript	designed and carried out the experiments, collected, and analyzed the results, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4411025	25915503	AD	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Performed field sampling|Contributed to the study design|Performed light and electron microscopic analyses|Reviewed and edited the manuscript, and approved its final version	Analyzed the data	Analyzed the data	Formal analysis	YES
4411025	25915503	AD	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Performed field sampling|Contributed to the study design|Performed light and electron microscopic analyses|Reviewed and edited the manuscript, and approved its final version	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411025	25915503	AD	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Performed field sampling|Contributed to the study design|Performed light and electron microscopic analyses|Reviewed and edited the manuscript, and approved its final version	Performed field sampling	Performed the experiments	Investigation	YES
4411025	25915503	AD	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Performed field sampling|Contributed to the study design|Performed light and electron microscopic analyses|Reviewed and edited the manuscript, and approved its final version	Contributed to the study design	Conceived and designed the experiments	Methodology	YES
4411025	25915503	AD	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Performed field sampling|Contributed to the study design|Performed light and electron microscopic analyses|Reviewed and edited the manuscript, and approved its final version	Performed light and electron microscopic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4411025	25915503	AD	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Performed field sampling|Contributed to the study design|Performed light and electron microscopic analyses|Reviewed and edited the manuscript, and approved its final version	Reviewed and edited the manuscript, and approved its final version	Wrote the paper	Writing - Review & Editing	YES
4411025	25915503	AV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Performed field sampling|Performed light and electron microscopic analyses|Reviewed and edited the manuscript, and approved its final version	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411025	25915503	AV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Performed field sampling|Performed light and electron microscopic analyses|Reviewed and edited the manuscript, and approved its final version	Performed the experiments	Performed the experiments	Investigation	YES
4411025	25915503	AV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Performed field sampling|Performed light and electron microscopic analyses|Reviewed and edited the manuscript, and approved its final version	Analyzed the data	Analyzed the data	Formal analysis	YES
4411025	25915503	AV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Performed field sampling|Performed light and electron microscopic analyses|Reviewed and edited the manuscript, and approved its final version	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411025	25915503	AV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Performed field sampling|Performed light and electron microscopic analyses|Reviewed and edited the manuscript, and approved its final version	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411025	25915503	AV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Performed field sampling|Performed light and electron microscopic analyses|Reviewed and edited the manuscript, and approved its final version	Performed field sampling	Performed the experiments	Investigation	YES
4411025	25915503	AV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Performed field sampling|Performed light and electron microscopic analyses|Reviewed and edited the manuscript, and approved its final version	Performed light and electron microscopic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4411025	25915503	AV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Performed field sampling|Performed light and electron microscopic analyses|Reviewed and edited the manuscript, and approved its final version	Reviewed and edited the manuscript, and approved its final version	Wrote the paper	Writing - Review & Editing	YES
4411025	25915503	GGP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Eleutheroschizon duboscqi in scoloplos armiger from the white sea and shared her findings with other authors for further collaboration, and contributed considerably to manuscript writing|Performed field sampling|Contributed to the study design|Performed light and electron microscopic analyses|Reviewed and edited the manuscript, and approved its final version	Analyzed the data	Analyzed the data	Formal analysis	YES
4411025	25915503	GGP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Eleutheroschizon duboscqi in scoloplos armiger from the white sea and shared her findings with other authors for further collaboration, and contributed considerably to manuscript writing|Performed field sampling|Contributed to the study design|Performed light and electron microscopic analyses|Reviewed and edited the manuscript, and approved its final version	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411025	25915503	GGP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Eleutheroschizon duboscqi in scoloplos armiger from the white sea and shared her findings with other authors for further collaboration, and contributed considerably to manuscript writing|Performed field sampling|Contributed to the study design|Performed light and electron microscopic analyses|Reviewed and edited the manuscript, and approved its final version	Eleutheroschizon duboscqi in scoloplos armiger from the white sea and shared her findings with other authors for further collaboration, and contributed considerably to manuscript writing	Wrote the paper	Writing - Original Draft	YES
4411025	25915503	GGP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Eleutheroschizon duboscqi in scoloplos armiger from the white sea and shared her findings with other authors for further collaboration, and contributed considerably to manuscript writing|Performed field sampling|Contributed to the study design|Performed light and electron microscopic analyses|Reviewed and edited the manuscript, and approved its final version	Performed field sampling	Performed the experiments	Investigation	YES
4411025	25915503	GGP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Eleutheroschizon duboscqi in scoloplos armiger from the white sea and shared her findings with other authors for further collaboration, and contributed considerably to manuscript writing|Performed field sampling|Contributed to the study design|Performed light and electron microscopic analyses|Reviewed and edited the manuscript, and approved its final version	Contributed to the study design	Conceived and designed the experiments	Methodology	YES
4411025	25915503	GGP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Eleutheroschizon duboscqi in scoloplos armiger from the white sea and shared her findings with other authors for further collaboration, and contributed considerably to manuscript writing|Performed field sampling|Contributed to the study design|Performed light and electron microscopic analyses|Reviewed and edited the manuscript, and approved its final version	Performed light and electron microscopic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4411025	25915503	GGP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Eleutheroschizon duboscqi in scoloplos armiger from the white sea and shared her findings with other authors for further collaboration, and contributed considerably to manuscript writing|Performed field sampling|Contributed to the study design|Performed light and electron microscopic analyses|Reviewed and edited the manuscript, and approved its final version	Reviewed and edited the manuscript, and approved its final version	Wrote the paper	Writing - Review & Editing	YES
4411025	25915503	MK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Performed light and electron microscopic analyses|Reviewed and edited the manuscript, and approved its final version	Analyzed the data	Analyzed the data	Formal analysis	YES
4411025	25915503	MK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Performed light and electron microscopic analyses|Reviewed and edited the manuscript, and approved its final version	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411025	25915503	MK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Performed light and electron microscopic analyses|Reviewed and edited the manuscript, and approved its final version	Performed light and electron microscopic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4411025	25915503	MK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Performed light and electron microscopic analyses|Reviewed and edited the manuscript, and approved its final version	Reviewed and edited the manuscript, and approved its final version	Wrote the paper	Writing - Review & Editing	YES
4411025	25915503	TGS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Performed field sampling|Contributed to the study design|Performed light and electron microscopic analyses|Reviewed and edited the manuscript, and approved its final version	Analyzed the data	Analyzed the data	Formal analysis	YES
4411025	25915503	TGS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Performed field sampling|Contributed to the study design|Performed light and electron microscopic analyses|Reviewed and edited the manuscript, and approved its final version	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411025	25915503	TGS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Performed field sampling|Contributed to the study design|Performed light and electron microscopic analyses|Reviewed and edited the manuscript, and approved its final version	Performed field sampling	Performed the experiments	Investigation	YES
4411025	25915503	TGS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Performed field sampling|Contributed to the study design|Performed light and electron microscopic analyses|Reviewed and edited the manuscript, and approved its final version	Contributed to the study design	Conceived and designed the experiments	Methodology	YES
4411025	25915503	TGS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Performed field sampling|Contributed to the study design|Performed light and electron microscopic analyses|Reviewed and edited the manuscript, and approved its final version	Performed light and electron microscopic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4411025	25915503	TGS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Performed field sampling|Contributed to the study design|Performed light and electron microscopic analyses|Reviewed and edited the manuscript, and approved its final version	Reviewed and edited the manuscript, and approved its final version	Wrote the paper	Writing - Review & Editing	YES
6291755	30548817	AA	PLoS52	were involved with the collection, preparation, and/or submission of the source data for the analysis	were involved with the collection, preparation, and/or submission of the source data for the analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6291755	30548817	AE	PLoS52	revised and finalized the concept|were involved with the collection, preparation, and/or submission of the source data for the analysis	revised and finalized the concept	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
6291755	30548817	AE	PLoS52	revised and finalized the concept|were involved with the collection, preparation, and/or submission of the source data for the analysis	were involved with the collection, preparation, and/or submission of the source data for the analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6291755	30548817	AHS	PLoS52	developed and wrote the analysis concept and analysis plan|revised and finalized the concept|were involved with the collection, preparation, and/or submission of the source data for the analysis|wrote the paper	developed and wrote the analysis concept and analysis plan	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
6291755	30548817	AHS	PLoS52	developed and wrote the analysis concept and analysis plan|revised and finalized the concept|were involved with the collection, preparation, and/or submission of the source data for the analysis|wrote the paper	revised and finalized the concept	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
6291755	30548817	AHS	PLoS52	developed and wrote the analysis concept and analysis plan|revised and finalized the concept|were involved with the collection, preparation, and/or submission of the source data for the analysis|wrote the paper	were involved with the collection, preparation, and/or submission of the source data for the analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6291755	30548817	AHS	PLoS52	developed and wrote the analysis concept and analysis plan|revised and finalized the concept|were involved with the collection, preparation, and/or submission of the source data for the analysis|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6291755	30548817	AK	PLoS52	developed and wrote the analysis concept and analysis plan|revised and finalized the concept|were involved with the collection, preparation, and/or submission of the source data for the analysis|conducted the analysis|wrote the paper	developed and wrote the analysis concept and analysis plan	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
6291755	30548817	AK	PLoS52	developed and wrote the analysis concept and analysis plan|revised and finalized the concept|were involved with the collection, preparation, and/or submission of the source data for the analysis|conducted the analysis|wrote the paper	revised and finalized the concept	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
6291755	30548817	AK	PLoS52	developed and wrote the analysis concept and analysis plan|revised and finalized the concept|were involved with the collection, preparation, and/or submission of the source data for the analysis|conducted the analysis|wrote the paper	were involved with the collection, preparation, and/or submission of the source data for the analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6291755	30548817	AK	PLoS52	developed and wrote the analysis concept and analysis plan|revised and finalized the concept|were involved with the collection, preparation, and/or submission of the source data for the analysis|conducted the analysis|wrote the paper	conducted the analysis	Performed the experiments	Investigation	YES
6291755	30548817	AK	PLoS52	developed and wrote the analysis concept and analysis plan|revised and finalized the concept|were involved with the collection, preparation, and/or submission of the source data for the analysis|conducted the analysis|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6291755	30548817	All co-authors	PLoS52	were involved with revisions of the paper, and read and approved the final version	were involved with revisions of the paper, and read and approved the final version	Wrote the paper	Writing - Review & Editing	YES
6291755	30548817	CM	PLoS52	revised and finalized the concept|were involved with the collection, preparation, and/or submission of the source data for the analysis	revised and finalized the concept	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
6291755	30548817	CM	PLoS52	revised and finalized the concept|were involved with the collection, preparation, and/or submission of the source data for the analysis	were involved with the collection, preparation, and/or submission of the source data for the analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6291755	30548817	DMM	PLoS52	were involved with the collection, preparation, and/or submission of the source data for the analysis	were involved with the collection, preparation, and/or submission of the source data for the analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6291755	30548817	ET	PLoS52	were involved with the collection, preparation, and/or submission of the source data for the analysis	were involved with the collection, preparation, and/or submission of the source data for the analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6291755	30548817	JP	PLoS52	were involved with the collection, preparation, and/or submission of the source data for the analysis	were involved with the collection, preparation, and/or submission of the source data for the analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6291755	30548817	KM	PLoS52	were involved with the collection, preparation, and/or submission of the source data for the analysis	were involved with the collection, preparation, and/or submission of the source data for the analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6291755	30548817	KWW	PLoS52	revised and finalized the concept|were involved with the collection, preparation, and/or submission of the source data for the analysis	revised and finalized the concept	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
6291755	30548817	KWW	PLoS52	revised and finalized the concept|were involved with the collection, preparation, and/or submission of the source data for the analysis	were involved with the collection, preparation, and/or submission of the source data for the analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6291755	30548817	LF	PLoS52	were involved with the collection, preparation, and/or submission of the source data for the analysis	were involved with the collection, preparation, and/or submission of the source data for the analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6291755	30548817	MAD	PLoS52	revised and finalized the concept|were involved with the collection, preparation, and/or submission of the source data for the analysis	revised and finalized the concept	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
6291755	30548817	MAD	PLoS52	revised and finalized the concept|were involved with the collection, preparation, and/or submission of the source data for the analysis	were involved with the collection, preparation, and/or submission of the source data for the analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6291755	30548817	ML	PLoS52	developed and wrote the analysis concept and analysis plan|revised and finalized the concept|were involved with the collection, preparation, and/or submission of the source data for the analysis|conducted the analysis	developed and wrote the analysis concept and analysis plan	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
6291755	30548817	ML	PLoS52	developed and wrote the analysis concept and analysis plan|revised and finalized the concept|were involved with the collection, preparation, and/or submission of the source data for the analysis|conducted the analysis	revised and finalized the concept	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
6291755	30548817	ML	PLoS52	developed and wrote the analysis concept and analysis plan|revised and finalized the concept|were involved with the collection, preparation, and/or submission of the source data for the analysis|conducted the analysis	were involved with the collection, preparation, and/or submission of the source data for the analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6291755	30548817	ML	PLoS52	developed and wrote the analysis concept and analysis plan|revised and finalized the concept|were involved with the collection, preparation, and/or submission of the source data for the analysis|conducted the analysis	conducted the analysis	Performed the experiments	Investigation	YES
6291755	30548817	MP	PLoS52	revised and finalized the concept	revised and finalized the concept	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
6291755	30548817	MV	PLoS52	were involved with the collection, preparation, and/or submission of the source data for the analysis	were involved with the collection, preparation, and/or submission of the source data for the analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6291755	30548817	MY	PLoS52	revised and finalized the concept|were involved with the collection, preparation, and/or submission of the source data for the analysis	revised and finalized the concept	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
6291755	30548817	MY	PLoS52	revised and finalized the concept|were involved with the collection, preparation, and/or submission of the source data for the analysis	were involved with the collection, preparation, and/or submission of the source data for the analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6291755	30548817	RH	PLoS52	revised and finalized the concept	revised and finalized the concept	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
6291755	30548817	RV	PLoS52	revised and finalized the concept|were involved with the collection, preparation, and/or submission of the source data for the analysis	revised and finalized the concept	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
6291755	30548817	RV	PLoS52	revised and finalized the concept|were involved with the collection, preparation, and/or submission of the source data for the analysis	were involved with the collection, preparation, and/or submission of the source data for the analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6291755	30548817	SA	PLoS52	revised and finalized the concept|were involved with the collection, preparation, and/or submission of the source data for the analysis	revised and finalized the concept	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
6291755	30548817	SA	PLoS52	revised and finalized the concept|were involved with the collection, preparation, and/or submission of the source data for the analysis	were involved with the collection, preparation, and/or submission of the source data for the analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6291755	30548817	VL	PLoS52	revised and finalized the concept|were involved with the collection, preparation, and/or submission of the source data for the analysis	revised and finalized the concept	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
6291755	30548817	VL	PLoS52	revised and finalized the concept|were involved with the collection, preparation, and/or submission of the source data for the analysis	were involved with the collection, preparation, and/or submission of the source data for the analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5651663	29093723	All authors	PLoS52	discussed the results|participated in completing the manuscript	discussed the results	-	-	NO
5651663	29093723	All authors	PLoS52	discussed the results|participated in completing the manuscript	participated in completing the manuscript	-	-	NO
5651663	29093723	HK	PLoS52	developed and performed the experiment|analyzed experimental data and processed images	developed and performed the experiment	Performed the experiments	Investigation	YES
5651663	29093723	HK	PLoS52	developed and performed the experiment|analyzed experimental data and processed images	analyzed experimental data and processed images	Analyzed the data	Data curation|Formal analysis|Visualization	YES
5651663	29093723	KK	PLoS52	proposed the study|developed and performed the experiment|analyzed experimental data and processed images|wrote the paper	proposed the study	Conceived and designed the experiments	Conceptualization	YES
5651663	29093723	KK	PLoS52	proposed the study|developed and performed the experiment|analyzed experimental data and processed images|wrote the paper	developed and performed the experiment	Performed the experiments	Investigation	YES
5651663	29093723	KK	PLoS52	proposed the study|developed and performed the experiment|analyzed experimental data and processed images|wrote the paper	analyzed experimental data and processed images	Analyzed the data	Data curation|Formal analysis|Visualization	YES
5651663	29093723	KK	PLoS52	proposed the study|developed and performed the experiment|analyzed experimental data and processed images|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5651663	29093723	SL	PLoS52	proposed the study	proposed the study	Conceived and designed the experiments	Conceptualization	YES
5651663	29093723	SP	PLoS52	developed and performed the experiment	developed and performed the experiment	Performed the experiments	Investigation	YES
1803026	17342208	JL	PLoS5	Conceived and designed the experiments|Wrote the paper|Contributed data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1803026	17342208	JL	PLoS5	Conceived and designed the experiments|Wrote the paper|Contributed data	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1803026	17342208	JL	PLoS5	Conceived and designed the experiments|Wrote the paper|Contributed data	Contributed data	Contributed reagents/materials/analysis tools	Resources	YES
1803026	17342208	KN	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1803026	17342208	KN	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1803026	17342208	KN	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1803026	17342208	LH	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1803026	17342208	LH	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5052733	27698033	A.P.	2	performed calculations	performed calculations	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5052733	27698033	All authors	2	analysed and interpreted data, drafted the article and approved the final version for publication	analysed and interpreted data, drafted the article and approved the final version for publication	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5052733	27698033	M.P.	2	performed calculations	performed calculations	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5052733	27698033	S.C.L.K.	2	performed calculations	performed calculations	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5483290	28646863	ARA	2	participated in the study design and coordinated sample collection	participated in the study design and coordinated sample collection	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Project administration	YES
5483290	28646863	EJG	2	were responsible for the conception, funding, study design, implementation of the project and managed data analysis	were responsible for the conception, funding, study design, implementation of the project and managed data analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Data curation|Formal analysis|Funding acquisition|Investigation|Methodology|Project administration	YES
5483290	28646863	JAW	2	were responsible for the conception, funding, study design, implementation of the project and managed data analysis	were responsible for the conception, funding, study design, implementation of the project and managed data analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Data curation|Formal analysis|Funding acquisition|Investigation|Methodology|Project administration	YES
5483290	28646863	MB	2	participated in the study design	participated in the study design	Conceived and designed the experiments	Methodology	YES
5483290	28646863	RAS	2	participated in the study design and coordinated sample collection	participated in the study design and coordinated sample collection	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Project administration	YES
5483290	28646863	SCB	2	were responsible for the conception, funding, study design, implementation of the project and managed data analysis|participated in the development of the research grants and provided guidance during the initial stages of analysis|contributed to the manuscript, read and approved the final manuscript	were responsible for the conception, funding, study design, implementation of the project and managed data analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Data curation|Formal analysis|Funding acquisition|Investigation|Methodology|Project administration	YES
5483290	28646863	SCB	2	were responsible for the conception, funding, study design, implementation of the project and managed data analysis|participated in the development of the research grants and provided guidance during the initial stages of analysis|contributed to the manuscript, read and approved the final manuscript	participated in the development of the research grants and provided guidance during the initial stages of analysis	-	Supervision	YES
5483290	28646863	SCB	2	were responsible for the conception, funding, study design, implementation of the project and managed data analysis|participated in the development of the research grants and provided guidance during the initial stages of analysis|contributed to the manuscript, read and approved the final manuscript	contributed to the manuscript, read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5483290	28646863	SHMcB	2	participated in the study design and coordinated sample collection	participated in the study design and coordinated sample collection	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Project administration	YES
5483290	28646863	SW	2	participated in the study design, carried out the statistical analysis and drafted the manuscript	participated in the study design, carried out the statistical analysis and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5483290	28646863	all authors	2	contributed to the manuscript, read and approved the final manuscript	contributed to the manuscript, read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4411027	25915926	JLW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411027	25915926	JLW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411027	25915926	JLW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411027	25915926	JLW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411027	25915926	JLW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411027	25915926	JMF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411027	25915926	JMF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411027	25915926	JMF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411027	25915926	JMF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411027	25915926	JMF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411027	25915926	JWG	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411027	25915926	JWG	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411027	25915926	SHB	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411027	25915926	SHB	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411027	25915926	SMW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411027	25915926	SMW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411027	25915926	SMW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411027	25915926	SMW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411027	25915926	TAM	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411027	25915926	TAM	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5052735	27698035	All authors	2	contributed to the concept and writing of the article	contributed to the concept and writing of the article	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
1803027	17327922	AL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1803027	17327922	AL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1803027	17327922	AL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1803027	17327922	AL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1803027	17327922	AL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1803027	17327922	AL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1803027	17327922	MT	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1803027	17327922	ZC	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1803027	17327922	ZC	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5651688	29093725	AG	2	designed the experiments|guided the experimental work	designed the experiments	Conceived and designed the experiments	Methodology	YES
5651688	29093725	AG	2	designed the experiments|guided the experimental work	guided the experimental work	Performed the experiments	Investigation|Supervision	YES
5651688	29093725	BN	2	designed the experiments|guided the experimental work	designed the experiments	Conceived and designed the experiments	Methodology	YES
5651688	29093725	BN	2	designed the experiments|guided the experimental work	guided the experimental work	Performed the experiments	Investigation|Supervision	YES
5651688	29093725	MH	2	designed the experiments|guided the experimental work	designed the experiments	Conceived and designed the experiments	Methodology	YES
5651688	29093725	MH	2	designed the experiments|guided the experimental work	guided the experimental work	Performed the experiments	Investigation|Supervision	YES
5651688	29093725	WB	2	designed the experiments|carried out the experiments, data analysis and prepared the figures	designed the experiments	Conceived and designed the experiments	Methodology	YES
5651688	29093725	WB	2	designed the experiments|carried out the experiments, data analysis and prepared the figures	carried out the experiments, data analysis and prepared the figures	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
6293134	30549217	All co-authors	2	contributed in designing the operational study|contributed to interpreting findings and writing the manuscript	contributed in designing the operational study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6293134	30549217	All co-authors	2	contributed in designing the operational study|contributed to interpreting findings and writing the manuscript	contributed to interpreting findings and writing the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6293134	30549217	BP	2	oversaw the data collection performed during the study	oversaw the data collection performed during the study	Performed the experiments	Investigation|Supervision	YES
6293134	30549217	BS	2	to write the first draft of the paper	to write the first draft of the paper	Wrote the paper	Writing - Original Draft	YES
6293134	30549217	RK	2	oversaw the data collection performed during the study|to write the first draft of the paper	oversaw the data collection performed during the study	Performed the experiments	Investigation|Supervision	YES
6293134	30549217	RK	2	oversaw the data collection performed during the study|to write the first draft of the paper	to write the first draft of the paper	Wrote the paper	Writing - Original Draft	YES
6293134	30549217	TA	2	to write the first draft of the paper	to write the first draft of the paper	Wrote the paper	Writing - Original Draft	YES
4411028	25915944	AW	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411028	25915944	AW	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411028	25915944	FZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411028	25915944	JW	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411028	25915944	JW	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411028	25915944	JW	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411028	25915944	JX	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411028	25915944	JZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411028	25915944	LZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411028	25915944	LZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411028	25915944	LZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411028	25915944	LZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411028	25915944	LZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411028	25915944	TT	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411028	25915944	YY	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5485680	28651543	BO	PLoS52	designed the experiments and drafted the manuscript	designed the experiments and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5485680	28651543	GZ	PLoS52	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5485680	28651543	HY	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5485680	28651543	ML	PLoS52	designed the experiments and drafted the manuscript|analyzed the data|carried out the experiments	designed the experiments and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5485680	28651543	ML	PLoS52	designed the experiments and drafted the manuscript|analyzed the data|carried out the experiments	analyzed the data	Analyzed the data	Formal analysis	YES
5485680	28651543	ML	PLoS52	designed the experiments and drafted the manuscript|analyzed the data|carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5485680	28651543	QH	PLoS52	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5485680	28651543	YL	PLoS52	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
4561934	26380280	Adelin Albert	2	contributed to the critical revision and intellectual content of the paper	contributed to the critical revision and intellectual content of the paper	Wrote the paper	Writing - Review & Editing	YES
4561934	26380280	All authors	2	contributed to the drafts and approved the final paper	contributed to the drafts and approved the final paper	Wrote the paper	Writing - Original Draft	YES
4561934	26380280	Anne-Francoise Donneau	2	are joint first authors	are joint first authors	-	-	NO
4561934	26380280	Axelle Hoge	2	was involved in the data collection and contributed to the critical discussion of the results	was involved in the data collection and contributed to the critical discussion of the results	Performed the experiments	Investigation	YES
4561934	26380280	Michele Guillaume	2	was the nescav project leader in wallonia and provided expertise and oversight throughout the process	was the nescav project leader in wallonia and provided expertise and oversight throughout the process	-	Supervision	YES
4561934	26380280	Philippe Kolh	2	cardiovascular surgeon and copromoter of the study, contributed to the critical revision of the paper	cardiovascular surgeon and copromoter of the study, contributed to the critical revision of the paper	Wrote the paper	Writing - Review & Editing	YES
4561934	26380280	Sven Majerus	2	contributed to the critical revision of the paper	contributed to the critical revision of the paper	Wrote the paper	Writing - Review & Editing	YES
4561934	26380280	Sylvie Streel	2	coordinated the field data collection in wallonia and drafted the present paper|to the paper|are joint first authors	coordinated the field data collection in wallonia and drafted the present paper	Performed the experiments|Wrote the paper	Investigation|Project administration|Writing - Original Draft	YES
4561934	26380280	Sylvie Streel	2	coordinated the field data collection in wallonia and drafted the present paper|to the paper|are joint first authors	to the paper	-	-	NO
4561934	26380280	Sylvie Streel	2	coordinated the field data collection in wallonia and drafted the present paper|to the paper|are joint first authors	are joint first authors	-	-	NO
3793319	24170980	Ahmed Omran	2	equally shared in this study	equally shared in this study	-	-	NO
3793319	24170980	Muhammad Usman Ashhab	2	equally shared in this study	equally shared in this study	-	-	NO
1803028	17342209	CC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1803028	17342209	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1803028	17342209	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1803028	17342209	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1803028	17342209	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1803028	17342209	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1803028	17342209	KR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1803028	17342209	KR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1803028	17342209	KR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1803028	17342209	KR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1803028	17342209	KR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1803028	17342209	PB	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1803028	17342209	PB	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5654479	29098001	DC	2	conceived and designed the experiment|analyzed the data and wrote the paper	conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5654479	29098001	DC	2	conceived and designed the experiment|analyzed the data and wrote the paper	analyzed the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5654479	29098001	ET	2	performed the evaluation|analyzed the data and wrote the paper	performed the evaluation	Performed the experiments	Investigation	YES
5654479	29098001	ET	2	performed the evaluation|analyzed the data and wrote the paper	analyzed the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5654479	29098001	MG	2	conceived and designed the experiment|performed the evaluation|analyzed the data and wrote the paper	conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5654479	29098001	MG	2	conceived and designed the experiment|performed the evaluation|analyzed the data and wrote the paper	performed the evaluation	Performed the experiments	Investigation	YES
5654479	29098001	MG	2	conceived and designed the experiment|performed the evaluation|analyzed the data and wrote the paper	analyzed the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6293147	30549245	All authors	2	contributed to manuscript writing and review	contributed to manuscript writing and review	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6293147	30549245	CAT	2	conceptualized the analysis|developed the analysis plan|conducted the data analysis	conceptualized the analysis	Conceived and designed the experiments	Conceptualization	YES
6293147	30549245	CAT	2	conceptualized the analysis|developed the analysis plan|conducted the data analysis	developed the analysis plan	-	-	NO
6293147	30549245	CAT	2	conceptualized the analysis|developed the analysis plan|conducted the data analysis	conducted the data analysis	Analyzed the data	Formal analysis	YES
6293147	30549245	EJA	2	conceptualized the analysis|developed the analysis plan	conceptualized the analysis	Conceived and designed the experiments	Conceptualization	YES
6293147	30549245	EJA	2	conceptualized the analysis|developed the analysis plan	developed the analysis plan	-	-	NO
6293147	30549245	KY	2	developed the analysis plan|conducted the data analysis	developed the analysis plan	-	-	NO
6293147	30549245	KY	2	developed the analysis plan|conducted the data analysis	conducted the data analysis	Analyzed the data	Formal analysis	YES
6293147	30549245	WME	2	conceptualized the analysis|developed the analysis plan	conceptualized the analysis	Conceived and designed the experiments	Conceptualization	YES
6293147	30549245	WME	2	conceptualized the analysis|developed the analysis plan	developed the analysis plan	-	-	NO
3348633	22611400	Gang Ren	2	are contributed equally to this work	are contributed equally to this work	-	-	NO
3348633	22611400	Jingwei Feng	2	are contributed equally to this work	are contributed equally to this work	-	-	NO
5485693	28651544	JKAS	2	wrote the draft and included comments from co-authors	wrote the draft and included comments from co-authors	Wrote the paper	Writing - Original Draft	YES
4411029	25915901	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411029	25915901	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411029	25915901	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411029	25915901	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411029	25915901	HK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411029	25915901	HK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411029	25915901	HK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411029	25915901	HK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411029	25915901	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411029	25915901	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411029	25915901	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411029	25915901	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1803029	17327915	FJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1803029	17327915	FJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1803029	17327915	FJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1803029	17327915	FJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1803029	17327915	JS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1803029	17327915	JS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1803029	17327915	JT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1803029	17327915	JT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1803029	17327915	JT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1803029	17327915	WF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1803029	17327915	WF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1803029	17327915	WF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5069528	29035258	All authors	2	worked together on developing the final manuscript	worked together on developing the final manuscript	Performed the experiments|Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5069528	29035258	M.L.	2	worked together on developing the final manuscript	worked together on developing the final manuscript	Performed the experiments|Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5069528	29035258	T.v.d.F.	2	designed the paper	designed the paper	Conceived and designed the experiments	-	YES
3793504	24170983	C. Ruiz	4	Study was designed by|The paper was drafted by	Study was designed by	Conceived and designed the experiments	Methodology	YES
3793504	24170983	C. Ruiz	4	Study was designed by|The paper was drafted by	The paper was drafted by	Wrote the paper	Writing - Original Draft	YES
3793504	24170983	E. De	4	Study was conducted by|The paper was drafted by	Study was conducted by	Performed the experiments	Investigation	YES
3793504	24170983	E. De	4	Study was conducted by|The paper was drafted by	The paper was drafted by	Wrote the paper	Writing - Original Draft	YES
3793504	24170983	M. Santin	4	The paper was drafted by	The paper was drafted by	Wrote the paper	Writing - Original Draft	YES
5654925	29104583	AB	2	contributed to the analysis and interpretation of the results and to the discussion section	contributed to the analysis and interpretation of the results and to the discussion section	Analyzed the data	Formal analysis	YES
5654925	29104583	AZ	2	planned and coordinated the study, performed data processing and analysis and wrote most of the main text	planned and coordinated the study, performed data processing and analysis and wrote most of the main text	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Data curation|Formal analysis|Project administration|Writing - Original Draft	YES
5654925	29104583	All authors	2	worked together to produce the final version of the text	worked together to produce the final version of the text	Performed the experiments	-	YES
5654925	29104583	BM	2	carried out the laser scanning measurements and the pre-processing of the point clouds, and wrote the methodology of the scanning	carried out the laser scanning measurements and the pre-processing of the point clouds, and wrote the methodology of the scanning	Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5654925	29104583	The authors	2	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	Performed the experiments	Investigation	YES
6294116	30549445	AJ	2	designed the study, contributed to data analyses and wrote the first draft of the manuscript|all contributed to interpretation of data, critically reviewed the manuscript and agreed on its final version	designed the study, contributed to data analyses and wrote the first draft of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
6294116	30549445	AJ	2	designed the study, contributed to data analyses and wrote the first draft of the manuscript|all contributed to interpretation of data, critically reviewed the manuscript and agreed on its final version	all contributed to interpretation of data, critically reviewed the manuscript and agreed on its final version	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
6294116	30549445	AT	2	all contributed to interpretation of data, critically reviewed the manuscript and agreed on its final version	all contributed to interpretation of data, critically reviewed the manuscript and agreed on its final version	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
6294116	30549445	DE	2	all contributed to interpretation of data, critically reviewed the manuscript and agreed on its final version	all contributed to interpretation of data, critically reviewed the manuscript and agreed on its final version	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
6294116	30549445	FD	2	all contributed to interpretation of data, critically reviewed the manuscript and agreed on its final version	all contributed to interpretation of data, critically reviewed the manuscript and agreed on its final version	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
6294116	30549445	GW	2	designed the study, contributed to data analyses and wrote the first draft of the manuscript|all contributed to interpretation of data, critically reviewed the manuscript and agreed on its final version	designed the study, contributed to data analyses and wrote the first draft of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
6294116	30549445	GW	2	designed the study, contributed to data analyses and wrote the first draft of the manuscript|all contributed to interpretation of data, critically reviewed the manuscript and agreed on its final version	all contributed to interpretation of data, critically reviewed the manuscript and agreed on its final version	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
6294116	30549445	LM	2	all contributed to interpretation of data, critically reviewed the manuscript and agreed on its final version	all contributed to interpretation of data, critically reviewed the manuscript and agreed on its final version	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
6294116	30549445	ME	2	all contributed to interpretation of data, critically reviewed the manuscript and agreed on its final version	all contributed to interpretation of data, critically reviewed the manuscript and agreed on its final version	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
6294116	30549445	MN	2	designed the study, contributed to data analyses and wrote the first draft of the manuscript|all contributed to interpretation of data, critically reviewed the manuscript and agreed on its final version	designed the study, contributed to data analyses and wrote the first draft of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
6294116	30549445	MN	2	designed the study, contributed to data analyses and wrote the first draft of the manuscript|all contributed to interpretation of data, critically reviewed the manuscript and agreed on its final version	all contributed to interpretation of data, critically reviewed the manuscript and agreed on its final version	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
6294116	30549445	MS	2	all contributed to interpretation of data, critically reviewed the manuscript and agreed on its final version	all contributed to interpretation of data, critically reviewed the manuscript and agreed on its final version	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
6294116	30549445	MV	2	designed the study, contributed to data analyses and wrote the first draft of the manuscript|all contributed to interpretation of data, critically reviewed the manuscript and agreed on its final version	designed the study, contributed to data analyses and wrote the first draft of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
6294116	30549445	MV	2	designed the study, contributed to data analyses and wrote the first draft of the manuscript|all contributed to interpretation of data, critically reviewed the manuscript and agreed on its final version	all contributed to interpretation of data, critically reviewed the manuscript and agreed on its final version	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
6294116	30549445	PC	2	all contributed to interpretation of data, critically reviewed the manuscript and agreed on its final version	all contributed to interpretation of data, critically reviewed the manuscript and agreed on its final version	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
4411030	25915415	LZL	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411030	25915415	TZ	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411030	25915415	TZ	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411030	25915415	XFC	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411030	25915415	XFC	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411030	25915415	ZZL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4411030	25915415	ZZL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5485702	28651633	AV	2	prepared samples and acquired data	prepared samples and acquired data	Performed the experiments	Investigation	YES
5485702	28651633	ES	2	developed methods and analyzed data	developed methods and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5485702	28651633	EVD	2	prepared samples and acquired data	prepared samples and acquired data	Performed the experiments	Investigation	YES
5485702	28651633	JG	2	developed methods and analyzed data	developed methods and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5485702	28651633	LS	2	conceived the study|prepared the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5485702	28651633	LS	2	conceived the study|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5485702	28651633	MB	2	prepared samples and acquired data|conceived the study	prepared samples and acquired data	Performed the experiments	Investigation	YES
5485702	28651633	MB	2	prepared samples and acquired data|conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5485702	28651633	MLK	2	prepared samples and acquired data	prepared samples and acquired data	Performed the experiments	Investigation	YES
5485702	28651633	OA	2	developed methods and analyzed data|conceived the study|prepared the manuscript	developed methods and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5485702	28651633	OA	2	developed methods and analyzed data|conceived the study|prepared the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5485702	28651633	OA	2	developed methods and analyzed data|conceived the study|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5485702	28651633	SD	2	prepared samples and acquired data|conceived the study	prepared samples and acquired data	Performed the experiments	Investigation	YES
5485702	28651633	SD	2	prepared samples and acquired data|conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
1803030	17342210	FF	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1803030	17342210	FF	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1803030	17342210	GT	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1803030	17342210	GT	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1803030	17342210	MM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1803030	17342210	MM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1803030	17342210	MP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1803030	17342210	RH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1803030	17342210	RH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1803030	17342210	RH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1803030	17342210	RH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1803030	17342210	RH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1803030	17342210	SE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1803030	17342210	SE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1803030	17342210	SE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1803030	17342210	SE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5069535	29035265	All authors	2	engaged in the discussions at the royal society and contributed to the preparation and revision of the manuscript	engaged in the discussions at the royal society and contributed to the preparation and revision of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4411031	25915051	CHL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411031	25915051	CHL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411031	25915051	YQZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411031	25915051	YQZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411031	25915051	YQZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411031	25915051	YQZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411031	25915051	YQZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411031	25915051	YY	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411031	25915051	YY	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411031	25915051	YY	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411031	25915051	YY	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6300754	30569625	GG	2	substantially contributed towards study design, data analysis, and interpretation of data, revision of the manuscript and approved the final version to be published	substantially contributed towards study design, data analysis, and interpretation of data, revision of the manuscript and approved the final version to be published	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Review & Editing	YES
6300754	30569625	JK	2	substantially contributed towards study design, data analysis, and interpretation of data, revision of the manuscript and approved the final version to be published	substantially contributed towards study design, data analysis, and interpretation of data, revision of the manuscript and approved the final version to be published	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Review & Editing	YES
6300754	30569625	JS	2	substantially contributed towards study design, data analysis, and interpretation of data, revision of the manuscript and approved the final version to be published	substantially contributed towards study design, data analysis, and interpretation of data, revision of the manuscript and approved the final version to be published	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Review & Editing	YES
6300754	30569625	LK	2	substantially contributed towards study design, data analysis, and interpretation of data, revision of the manuscript and approved the final version to be published	substantially contributed towards study design, data analysis, and interpretation of data, revision of the manuscript and approved the final version to be published	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Review & Editing	YES
6300754	30569625	NM	2	substantially contributed towards study design, data analysis, and interpretation of data, revision of the manuscript and approved the final version to be published	substantially contributed towards study design, data analysis, and interpretation of data, revision of the manuscript and approved the final version to be published	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Review & Editing	YES
6300754	30569625	NN	2	substantially contributed towards study design, data analysis, and interpretation of data, revision of the manuscript and approved the final version to be published	substantially contributed towards study design, data analysis, and interpretation of data, revision of the manuscript and approved the final version to be published	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Review & Editing	YES
6300754	30569625	SJ	2	substantially contributed towards study design, data analysis, and interpretation of data, revision of the manuscript and approved the final version to be published	substantially contributed towards study design, data analysis, and interpretation of data, revision of the manuscript and approved the final version to be published	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Review & Editing	YES
6300754	30569625	SS	2	conceived and designed the study and led the data collection, analysis and interpretation of data, drafted the article, led the revisions and approved the version to be published	conceived and designed the study and led the data collection, analysis and interpretation of data, drafted the article, led the revisions and approved the version to be published	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
6300754	30569625	TF	2	substantially contributed towards study design, data analysis, and interpretation of data, revision of the manuscript and approved the final version to be published	substantially contributed towards study design, data analysis, and interpretation of data, revision of the manuscript and approved the final version to be published	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Review & Editing	YES
1804098	17356693	RB	PLoS5	Wrote the paper|Performed computer simulations	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1804098	17356693	RB	PLoS5	Wrote the paper|Performed computer simulations	Performed computer simulations	Performed the experiments	Formal analysis|Investigation	YES
1804098	17356693	RV	PLoS5	Wrote the paper|Performed computer simulations	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1804098	17356693	RV	PLoS5	Wrote the paper|Performed computer simulations	Performed computer simulations	Performed the experiments	Formal analysis|Investigation	YES
1804098	17356693	SB	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5654942	29104578	All authors	2	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5654942	29104578	EA	2	conceived the experiment|wrote the manuscript	conceived the experiment	Conceived and designed the experiments	Conceptualization	YES
5654942	29104578	EA	2	conceived the experiment|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5654942	29104578	GG	2	conceived the experiment|conducted the experiment|analyzed the results|wrote the manuscript	conceived the experiment	Conceived and designed the experiments	Conceptualization	YES
5654942	29104578	GG	2	conceived the experiment|conducted the experiment|analyzed the results|wrote the manuscript	conducted the experiment	Performed the experiments	Investigation	YES
5654942	29104578	GG	2	conceived the experiment|conducted the experiment|analyzed the results|wrote the manuscript	analyzed the results	Analyzed the data	Formal analysis	YES
5654942	29104578	GG	2	conceived the experiment|conducted the experiment|analyzed the results|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5654942	29104578	MO	2	conducted the experiment	conducted the experiment	Performed the experiments	Investigation	YES
5654942	29104578	PS	2	conducted the experiment	conducted the experiment	Performed the experiments	Investigation	YES
3793540	24170981	Nabia Nazir	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
3793540	24170981	Shahid Iqbal	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
5485742	28651538	D.W.	2	provided input in the role of the predicted regulators in chromatin regulation|edited the manuscript	provided input in the role of the predicted regulators in chromatin regulation	Analyzed the data	Formal analysis	YES
5485742	28651538	D.W.	2	provided input in the role of the predicted regulators in chromatin regulation|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5485742	28651538	F.B.	2	analyzed the predictions|conducted the phenotypic characterization of chiq1-1 and complemented lines	analyzed the predictions	Analyzed the data	Formal analysis	YES
5485742	28651538	F.B.	2	analyzed the predictions|conducted the phenotypic characterization of chiq1-1 and complemented lines	conducted the phenotypic characterization of chiq1-1 and complemented lines	Performed the experiments	Investigation	YES
5485742	28651538	IP	2	pull-down assays, and generated and analyzed chiq1 transgenic lines	pull-down assays, and generated and analyzed chiq1 transgenic lines	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5485742	28651538	J.F.	2	analyzed the predictions|edited the manuscript	analyzed the predictions	Analyzed the data	Formal analysis	YES
5485742	28651538	J.F.	2	analyzed the predictions|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5485742	28651538	J.X.	2	edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5485742	28651538	L.C.	2	conducted the phenotypic characterization of chiq1-1 and complemented lines	conducted the phenotypic characterization of chiq1-1 and complemented lines	Performed the experiments	Investigation	YES
5485742	28651538	S.Y.R.	2	analyzed the predictions	analyzed the predictions	Analyzed the data	Formal analysis	YES
5485742	28651538	Y.D.	2	edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5069537	29035267	A.M.	2	organized the vast reference list	organized the vast reference list	-	-	NO
5069537	29035267	A.M.S.	2	contributed written examples and figures for the review section of the manuscript	contributed written examples and figures for the review section of the manuscript	Wrote the paper	Visualization|Writing - Original Draft|Writing - Review & Editing	YES
5069537	29035267	All authors	2	gave final approval for publication	gave final approval for publication	-	-	NO
5069537	29035267	C.J.	2	contributed written examples and figures for the review section of the manuscript	contributed written examples and figures for the review section of the manuscript	Wrote the paper	Visualization|Writing - Original Draft|Writing - Review & Editing	YES
5069537	29035267	D.P.	2	contributed written examples and figures for the review section of the manuscript	contributed written examples and figures for the review section of the manuscript	Wrote the paper	Visualization|Writing - Original Draft|Writing - Review & Editing	YES
5069537	29035267	F.D.	2	contributed written examples and figures for the review section of the manuscript	contributed written examples and figures for the review section of the manuscript	Wrote the paper	Visualization|Writing - Original Draft|Writing - Review & Editing	YES
5069537	29035267	G.A.C.	2	wrote the introduction	wrote the introduction	Wrote the paper	Writing - Original Draft	YES
5069537	29035267	H.T.	2	contributed written examples and figures for the review section of the manuscript	contributed written examples and figures for the review section of the manuscript	Wrote the paper	Visualization|Writing - Original Draft|Writing - Review & Editing	YES
5069537	29035267	M.A.C.	2	wrote the manuscript with significant written contributions or editorial comments from all authors	wrote the manuscript with significant written contributions or editorial comments from all authors	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5069537	29035267	P.S.A.	2	contributed written examples and figures for the review section of the manuscript	contributed written examples and figures for the review section of the manuscript	Wrote the paper	Visualization|Writing - Original Draft|Writing - Review & Editing	YES
5069537	29035267	P.W.B.	2	contributed written examples and figures for the review section of the manuscript	contributed written examples and figures for the review section of the manuscript	Wrote the paper	Visualization|Writing - Original Draft|Writing - Review & Editing	YES
5069537	29035267	TEI	2	shelf flux gauge	shelf flux gauge	-	-	NO
5069537	29035267	V.H.	2	wrote the introduction	wrote the introduction	Wrote the paper	Writing - Original Draft	YES
5069537	29035267	W.B.H.	2	contributed written examples and figures for the review section of the manuscript	contributed written examples and figures for the review section of the manuscript	Wrote the paper	Visualization|Writing - Original Draft|Writing - Review & Editing	YES
4411032	25915053	DM	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411032	25915053	DM	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411032	25915053	JFRP	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411032	25915053	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411032	25915053	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411032	25915053	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411032	25915053	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411032	25915053	MPG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411032	25915053	MPG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411032	25915053	MPG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411032	25915053	MPG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1804099	17356692	FS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1804099	17356692	FS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1804099	17356692	FS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1804099	17356692	FS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1804099	17356692	FS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1804099	17356692	SM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1804099	17356692	SM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1804099	17356692	SM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1804099	17356692	SM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6322485	30615271	CO	2	contributed to editing of the article	contributed to editing of the article	Wrote the paper	Writing - Review & Editing	YES
6322485	30615271	DR	2	contributed to acquisition of data, data analysis and interpretation	contributed to acquisition of data, data analysis and interpretation	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
6322485	30615271	IA	2	contributed to editing of the article	contributed to editing of the article	Wrote the paper	Writing - Review & Editing	YES
6322485	30615271	IW	2	contributed to editing of the article	contributed to editing of the article	Wrote the paper	Writing - Review & Editing	YES
6322485	30615271	IYJ	2	wrote the first draft of the manuscript and interpreted the results	wrote the first draft of the manuscript and interpreted the results	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6322485	30615271	JYC	2	contributed to conceptualization and design of the study	contributed to conceptualization and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6322485	30615271	MG	2	contributed to editing of the article	contributed to editing of the article	Wrote the paper	Writing - Review & Editing	YES
6322485	30615271	all authors	2	have read and approved the final manuscript	have read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5654954	29104585	MR	2	conceived the premise for this review	conceived the premise for this review	Conceived and designed the experiments	Conceptualization	YES
5654954	29104585	YC	2	conceived the premise for this review	conceived the premise for this review	Conceived and designed the experiments	Conceptualization	YES
548683	15676076	DN	2	isolated full length fam20a cdna, performed transfection experiments and drafted the manuscript	isolated full length fam20a cdna, performed transfection experiments and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
548683	15676076	EC	2	provided reagents and assistance in performing rt pcr assays	provided reagents and assistance in performing rt pcr assays	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
548683	15676076	EGB	2	provided reagents and assistance in performing rt pcr assays	provided reagents and assistance in performing rt pcr assays	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
548683	15676076	HY	2	performed rt pcr assays	performed rt pcr assays	Performed the experiments	Investigation	YES
548683	15676076	IN	2	assisted in construction of expression vectors	assisted in construction of expression vectors	Performed the experiments	Investigation	YES
548683	15676076	SCW	2	directed the project and performed genomics analyses|also wrote the final draft of the manuscript and all authors read and approved this version	directed the project and performed genomics analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Supervision	YES
548683	15676076	SCW	2	directed the project and performed genomics analyses|also wrote the final draft of the manuscript and all authors read and approved this version	also wrote the final draft of the manuscript and all authors read and approved this version	Wrote the paper	Writing - Original Draft	YES
548683	15676076	SS	2	performed genomics analyses	performed genomics analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4411033	25915951	AN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411033	25915951	AN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411033	25915951	AN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411033	25915951	AN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411033	25915951	AO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411033	25915951	AO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411033	25915951	AO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411033	25915951	AO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411033	25915951	AV	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411033	25915951	AV	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411033	25915951	AV	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411033	25915951	CsC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411033	25915951	CsL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411033	25915951	CsL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411033	25915951	CsL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411033	25915951	CsL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411033	25915951	CsL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411033	25915951	ECs	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411033	25915951	ECs	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411033	25915951	ECs	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411033	25915951	HG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411033	25915951	IB	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411033	25915951	IB	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411033	25915951	JGP	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411033	25915951	JGP	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411033	25915951	SM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411033	25915951	TF	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4411033	25915951	TF	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411033	25915951	TTV	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4411033	25915951	TTV	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411033	25915951	TW	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411033	25915951	ZsV	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411033	25915951	ZsV	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411033	25915951	ZsV	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5069538	29035268	A.R.B.	2	involved all authors|commented on by all authors	involved all authors	-	-	NO
5069538	29035268	A.R.B.	2	involved all authors|commented on by all authors	commented on by all authors	-	-	NO
5069538	29035268	All authors	2	contributed text	contributed text	Wrote the paper	Writing - Original Draft	YES
5069538	29035268	W.M.L.	2	involved all authors|commented on by all authors	involved all authors	-	-	NO
5069538	29035268	W.M.L.	2	involved all authors|commented on by all authors	commented on by all authors	-	-	NO
3159907	21906327	CHY	2	conceived of the study, participated in its design and coordination and wrote the manuscript	conceived of the study, participated in its design and coordination and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
3159907	21906327	DHK	2	carried out the molecular genetic studies and the assay of fatty acid hydroxylation	carried out the molecular genetic studies and the assay of fatty acid hydroxylation	Performed the experiments	Investigation	YES
3159907	21906327	DK	2	participated in the sequence alignment and performed the statistical analysis	participated in the sequence alignment and performed the statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3159907	21906327	HCJ	2	conceived of the study and participated in the design of the study	conceived of the study and participated in the design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3159907	21906327	HZC	2	participated in the design of the study	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
3159907	21906327	JGP	2	participated in the design of the study	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
3159907	21906327	JYK	2	carried out the molecular genetic studies and the assay of fatty acid hydroxylation	carried out the molecular genetic studies and the assay of fatty acid hydroxylation	Performed the experiments	Investigation	YES
3159907	21906327	KHK	2	carried out the assay of human drug substrate oxidation	carried out the assay of human drug substrate oxidation	Performed the experiments	Investigation	YES
3159907	21906327	SHP	2	carried out the assay of human drug substrate oxidation	carried out the assay of human drug substrate oxidation	Performed the experiments	Investigation	YES
3159907	21906327	SMS	2	carried out the molecular genetic studies and the assay of fatty acid hydroxylation	carried out the molecular genetic studies and the assay of fatty acid hydroxylation	Performed the experiments	Investigation	YES
3159907	21906327	SYK	2	carried out the molecular genetic studies and the assay of fatty acid hydroxylation	carried out the molecular genetic studies and the assay of fatty acid hydroxylation	Performed the experiments	Investigation	YES
3159907	21906327	TA	2	participated in the design of the study	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
3159907	21906327	YHJ	2	conceived of the study and participated in the design of the study	conceived of the study and participated in the design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3159907	21906327	YTC	2	participated in the design of the study	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
4411034	25915529	AE	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411034	25915529	AS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411034	25915529	ESESES	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411034	25915529	ESESES	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411034	25915529	GE	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411034	25915529	GE	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411034	25915529	II	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411034	25915529	II	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411034	25915529	II	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411034	25915529	MAR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411034	25915529	MAR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411034	25915529	MAR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411034	25915529	MAR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411034	25915529	MAR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411034	25915529	MAT	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411034	25915529	MAT	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411034	25915529	MAY	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411034	25915529	MAY	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411034	25915529	MEA	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4411034	25915529	MO	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411034	25915529	NY	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411034	25915529	NY	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411034	25915529	NY	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411034	25915529	SAESES	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411034	25915529	SAESES	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411034	25915529	SAESES	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411034	25915529	SAESES	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411034	25915529	SAESES	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411034	25915529	SEK	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411034	25915529	SEK	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1804100	17330140	DR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1804100	17330140	DR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1804100	17330140	DR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1804100	17330140	DR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
548691	15693999	AV	2	coordinated the project and finalized the manuscript	coordinated the project and finalized the manuscript	Wrote the paper	Project administration|Writing - Review & Editing	YES
548691	15693999	FV	2	carried out the molecular study	carried out the molecular study	Performed the experiments	Investigation	YES
548691	15693999	KF	2	carried out the molecular study	carried out the molecular study	Performed the experiments	Investigation	YES
548691	15693999	MD	2	carried out the molecular study	carried out the molecular study	Performed the experiments	Investigation	YES
548691	15693999	MM	2	made the chickrh6 panel	made the chickrh6 panel	-	-	NO
548691	15693999	SB	2	carried out the molecular study	carried out the molecular study	Performed the experiments	Investigation	YES
548691	15693999	SL	2	carried out the molecular study	carried out the molecular study	Performed the experiments	Investigation	YES
5655013	29104582	All authors	PLoS52	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5655013	29104582	HS	PLoS52	carried out the experiments|performed data analysis	carried out the experiments	Performed the experiments	Investigation	YES
5655013	29104582	HS	PLoS52	carried out the experiments|performed data analysis	performed data analysis	Analyzed the data	Formal analysis	YES
5655013	29104582	HZ	PLoS52	designed and supervised the research	designed and supervised the research	Conceived and designed the experiments	Methodology|Supervision	YES
5655013	29104582	LX	PLoS52	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5655013	29104582	QY	PLoS52	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5655013	29104582	TS	PLoS52	carried out the experiments|performed data analysis	carried out the experiments	Performed the experiments	Investigation	YES
5655013	29104582	TS	PLoS52	carried out the experiments|performed data analysis	performed data analysis	Analyzed the data	Formal analysis	YES
5655013	29104582	YY	PLoS52	designed and supervised the research|wrote the paper	designed and supervised the research	Conceived and designed the experiments	Methodology|Supervision	YES
5655013	29104582	YY	PLoS52	designed and supervised the research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6327944	30629340	ASC	PLoS52	performed the research|analysed the data|critically revised the manuscript	performed the research	Performed the experiments	Investigation	YES
6327944	30629340	ASC	PLoS52	performed the research|analysed the data|critically revised the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
6327944	30629340	ASC	PLoS52	performed the research|analysed the data|critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
6327944	30629340	BA	PLoS52	analysed the data|critically revised the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
6327944	30629340	BA	PLoS52	analysed the data|critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
6327944	30629340	CL	PLoS52	performed the research	performed the research	Performed the experiments	Investigation	YES
6327944	30629340	CR	PLoS52	designed the research study|analysed the data|wrote the paper	designed the research study	Conceived and designed the experiments	Methodology	YES
6327944	30629340	CR	PLoS52	designed the research study|analysed the data|wrote the paper	analysed the data	Analyzed the data	Formal analysis	YES
6327944	30629340	CR	PLoS52	designed the research study|analysed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6327944	30629340	EG	PLoS52	performed the research	performed the research	Performed the experiments	Investigation	YES
6327944	30629340	FB	PLoS52	designed the research study|performed the research|analysed the data|critically revised the manuscript	designed the research study	Conceived and designed the experiments	Methodology	YES
6327944	30629340	FB	PLoS52	designed the research study|performed the research|analysed the data|critically revised the manuscript	performed the research	Performed the experiments	Investigation	YES
6327944	30629340	FB	PLoS52	designed the research study|performed the research|analysed the data|critically revised the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
6327944	30629340	FB	PLoS52	designed the research study|performed the research|analysed the data|critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
6327944	30629340	LM	PLoS52	analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
6327944	30629340	NN	PLoS52	performed the research	performed the research	Performed the experiments	Investigation	YES
6327944	30629340	OL	PLoS52	designed the research study|analysed the data|critically revised the manuscript	designed the research study	Conceived and designed the experiments	Methodology	YES
6327944	30629340	OL	PLoS52	designed the research study|analysed the data|critically revised the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
6327944	30629340	OL	PLoS52	designed the research study|analysed the data|critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
6327944	30629340	PL	PLoS52	performed the research	performed the research	Performed the experiments	Investigation	YES
6327944	30629340	PT	PLoS52	performed the research	performed the research	Performed the experiments	Investigation	YES
6327944	30629340	TB	PLoS52	performed the research|analysed the data|critically revised the manuscript	performed the research	Performed the experiments	Investigation	YES
6327944	30629340	TB	PLoS52	performed the research|analysed the data|critically revised the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
6327944	30629340	TB	PLoS52	performed the research|analysed the data|critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
6327944	30629340	VAF	PLoS52	designed the research study|performed the research|analysed the data|wrote the paper	designed the research study	Conceived and designed the experiments	Methodology	YES
6327944	30629340	VAF	PLoS52	designed the research study|performed the research|analysed the data|wrote the paper	performed the research	Performed the experiments	Investigation	YES
6327944	30629340	VAF	PLoS52	designed the research study|performed the research|analysed the data|wrote the paper	analysed the data	Analyzed the data	Formal analysis	YES
6327944	30629340	VAF	PLoS52	designed the research study|performed the research|analysed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6327944	30629340	VM	PLoS52	performed the research	performed the research	Performed the experiments	Investigation	YES
4561943	26380281	Hsiang-Jui Huang	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
4561943	26380281	Hui-Min Ting	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
4561943	26380281	Hui-Min Ting	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
4561943	26380281	Hung-Yu Wang	PLoS52	performed the experiments|contributed materials and analysis tools	performed the experiments	Performed the experiments	Investigation	YES
4561943	26380281	Hung-Yu Wang	PLoS52	performed the experiments|contributed materials and analysis tools	contributed materials and analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4561943	26380281	Li-Fu Wu	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
4561943	26380281	Li-Fu Wu	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
4561943	26380281	Pei-Ju Chao	PLoS52	performed the experiments|analyzed the data|contributed materials and analysis tools	performed the experiments	Performed the experiments	Investigation	YES
4561943	26380281	Pei-Ju Chao	PLoS52	performed the experiments|analyzed the data|contributed materials and analysis tools	analyzed the data	Analyzed the data	Formal analysis	YES
4561943	26380281	Pei-Ju Chao	PLoS52	performed the experiments|analyzed the data|contributed materials and analysis tools	contributed materials and analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4561943	26380281	Shih-Sian Guo	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
4561943	26380281	Shu-Yuan Lin	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
4561943	26380281	Tsair-Fwu Lee	PLoS52	conceived and designed the experiments|analyzed the data|contributed materials and analysis tools	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4561943	26380281	Tsair-Fwu Lee	PLoS52	conceived and designed the experiments|analyzed the data|contributed materials and analysis tools	analyzed the data	Analyzed the data	Formal analysis	YES
4561943	26380281	Tsair-Fwu Lee	PLoS52	conceived and designed the experiments|analyzed the data|contributed materials and analysis tools	contributed materials and analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4561943	26380281	Wei-Chun Lin	PLoS52	conceived and designed the experiments|analyzed the data	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4561943	26380281	Wei-Chun Lin	PLoS52	conceived and designed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
3159908	21906329	All authors	2	contributed to the scientific discussion throughout the work and have read and approved the final manuscript	contributed to the scientific discussion throughout the work and have read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
3159908	21906329	BHH	2	participated in the design of the study and commented on the manuscript	participated in the design of the study and commented on the manuscript	Conceived and designed the experiments	Methodology	YES
3159908	21906329	DR	2	participated in the design of the study, constructed the strains and commented on the manuscript	participated in the design of the study, constructed the strains and commented on the manuscript	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3159908	21906329	GL	2	participated in the design of the study and commented on the manuscript	participated in the design of the study and commented on the manuscript	Conceived and designed the experiments	Methodology	YES
3159908	21906329	KO	2	participated in the design of the study, performed the experimental work and wrote the manuscript	participated in the design of the study, performed the experimental work and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
1804101	17342207	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1804101	17342207	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1804101	17342207	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1804101	17342207	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5655017	29104580	CG-B	PLoS52	planned and designed the research	planned and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5655017	29104580	DAB	PLoS52	callose staining	callose staining	Performed the experiments	Investigation	YES
5655017	29104580	EF-C	PLoS52	realized hormonal analysis, qpcr procedures|analyzing the results and wrote the manuscript with the technical support of cg-b who participated in drafting the manuscript as well	realized hormonal analysis, qpcr procedures	Performed the experiments	Investigation	YES
5655017	29104580	EF-C	PLoS52	realized hormonal analysis, qpcr procedures|analyzing the results and wrote the manuscript with the technical support of cg-b who participated in drafting the manuscript as well	analyzing the results and wrote the manuscript with the technical support of cg-b who participated in drafting the manuscript as well	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5655017	29104580	IF	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5655017	29104580	JN	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5655017	29104580	MS-S	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5655017	29104580	PG-A	PLoS52	planned and designed the research|participated in the correction of manuscript	planned and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5655017	29104580	PG-A	PLoS52	planned and designed the research|participated in the correction of manuscript	participated in the correction of manuscript	Wrote the paper	Writing - Review & Editing	YES
5655017	29104580	VP	PLoS52	planned and designed the research|participated in the correction of manuscript	planned and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5655017	29104580	VP	PLoS52	planned and designed the research|participated in the correction of manuscript	participated in the correction of manuscript	Wrote the paper	Writing - Review & Editing	YES
4411035	25915650	GM	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411035	25915650	GM	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411035	25915650	ILK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411035	25915650	ILK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411035	25915650	ILK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411035	25915650	ILK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411035	25915650	MOA	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411035	25915650	MOA	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411035	25915650	MS	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411035	25915650	MS	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411035	25915650	VGHE	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411035	25915650	VGHE	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3159909	21906328	AO	2	participated in design and coordination of this study	participated in design and coordination of this study	Conceived and designed the experiments	Methodology|Project administration	YES
3159909	21906328	HB	2	carried out an assay of antifungal activity	carried out an assay of antifungal activity	Performed the experiments	Investigation	YES
3159909	21906328	HT	2	participated in all experiments except an assay of antifungal activity	participated in all experiments except an assay of antifungal activity	Performed the experiments	Investigation	YES
3159909	21906328	KF	2	participated in design and coordination of this study	participated in design and coordination of this study	Conceived and designed the experiments	Methodology|Project administration	YES
3159909	21906328	MY	2	participated in all experiments except an assay of antifungal activity	participated in all experiments except an assay of antifungal activity	Performed the experiments	Investigation	YES
3159909	21906328	TT	2	participated in design and coordination of this study	participated in design and coordination of this study	Conceived and designed the experiments	Methodology|Project administration	YES
5488345	28655292	HERV	2	insertional polymorphisms	insertional polymorphisms	-	-	NO
5488345	28655292	HS	2	designed the study and wrote the manuscript	designed the study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5488345	28655292	HT	2	participated in the acquisition and interpretation of data	participated in the acquisition and interpretation of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5488345	28655292	NK	2	participated in the acquisition and interpretation of data	participated in the acquisition and interpretation of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5488345	28655292	TK	2	designed the study and wrote the manuscript|developed the algorithm to estimate the tsd lengths and performed genotyping	designed the study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5488345	28655292	TK	2	designed the study and wrote the manuscript|developed the algorithm to estimate the tsd lengths and performed genotyping	developed the algorithm to estimate the tsd lengths and performed genotyping	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Software	YES
6338102	30657642	All authors	2	critically reviewed and approved the final version	critically reviewed and approved the final version	-	-	NO
6338102	30657642	CLC	2	provided feedback on emerging findings from the qualitative study and reviewed and provided comments on the manuscript	provided feedback on emerging findings from the qualitative study and reviewed and provided comments on the manuscript	Wrote the paper	Writing - Review & Editing	YES
6338102	30657642	ENJ	2	analysed the data for this report, and wrote and revised the manuscript	analysed the data for this report, and wrote and revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
6338102	30657642	ETK	2	supervised data collection at the qualitative study sites	supervised data collection at the qualitative study sites	Performed the experiments	Investigation|Supervision	YES
6338102	30657642	JMB	2	provided feedback on emerging findings from the qualitative study and reviewed and provided comments on the manuscript	provided feedback on emerging findings from the qualitative study and reviewed and provided comments on the manuscript	Wrote the paper	Writing - Review & Editing	YES
6338102	30657642	MAW	2	designed the qualitative research	designed the qualitative research	Conceived and designed the experiments	Methodology	YES
6338102	30657642	NCW	2	designed the qualitative research|analysed the data for this report, and wrote and revised the manuscript	designed the qualitative research	Conceived and designed the experiments	Methodology	YES
6338102	30657642	NCW	2	designed the qualitative research|analysed the data for this report, and wrote and revised the manuscript	analysed the data for this report, and wrote and revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
6338102	30657642	SBA	2	supervised data collection at the qualitative study sites	supervised data collection at the qualitative study sites	Performed the experiments	Investigation|Supervision	YES
6338102	30657642	TRM	2	supervised data collection at the qualitative study sites	supervised data collection at the qualitative study sites	Performed the experiments	Investigation|Supervision	YES
5069539	29035270	A.T.	2	who enabled the gridding and presentation of data products	who enabled the gridding and presentation of data products	-	-	NO
5069539	29035270	All authors	2	assisted in critically refining the manuscript and approved its final version	assisted in critically refining the manuscript and approved its final version	-	-	NO
5069539	29035270	C.J.	2	who enabled the gridding and presentation of data products	who enabled the gridding and presentation of data products	-	-	NO
5069539	29035270	S.S.	2	chaired, collectively leading to the conception and design of this manuscript	chaired, collectively leading to the conception and design of this manuscript	Conceived and designed the experiments	Conceptualization	YES
5069539	29035270	W.B.H.	2	who enabled the gridding and presentation of data products	who enabled the gridding and presentation of data products	-	-	NO
5069539	29035270	W.M.B.	2	chaired, collectively leading to the conception and design of this manuscript	chaired, collectively leading to the conception and design of this manuscript	Conceived and designed the experiments	Conceptualization	YES
1804102	17356690	DG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1804102	17356690	DG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1804102	17356690	DG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1804102	17356690	DG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1804102	17356690	DG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1804102	17356690	FH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1804102	17356690	FH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1804102	17356690	FH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1804102	17356690	HV	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1804102	17356690	JB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1804102	17356690	JB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1804102	17356690	JB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1804102	17356690	JB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1804102	17356690	SL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1804102	17356690	SL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1804102	17356690	SL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1804102	17356690	SP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1804102	17356690	SP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1804102	17356690	SP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1804102	17356690	SP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1804102	17356690	SP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411036	25915899	CMB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Development of the spatial models and code	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411036	25915899	CMB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Development of the spatial models and code	Analyzed the data	Analyzed the data	Formal analysis	YES
4411036	25915899	CMB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Development of the spatial models and code	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411036	25915899	CMB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Development of the spatial models and code	Development of the spatial models and code	Performed the experiments	Methodology|Software	YES
4411036	25915899	JFC	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411036	25915899	JFC	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411036	25915899	RA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411036	25915899	RA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411036	25915899	RA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411036	25915899	SM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411036	25915899	SM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411036	25915899	SM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5655018	29104581	AD	2	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5655018	29104581	AK	2	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5655018	29104581	BG	2	generated the genetic diversity data	generated the genetic diversity data	Performed the experiments	Investigation	YES
5655018	29104581	CJ	2	planned the study|wrote the first draft of the paper and all authors assisted with the development of the final draft	planned the study	Conceived and designed the experiments	Conceptualization	YES
5655018	29104581	CJ	2	planned the study|wrote the first draft of the paper and all authors assisted with the development of the final draft	wrote the first draft of the paper and all authors assisted with the development of the final draft	Wrote the paper	Writing - Original Draft	YES
5655018	29104581	JD	2	planned the study|wrote the first draft of the paper and all authors assisted with the development of the final draft	planned the study	Conceived and designed the experiments	Conceptualization	YES
5655018	29104581	JD	2	planned the study|wrote the first draft of the paper and all authors assisted with the development of the final draft	wrote the first draft of the paper and all authors assisted with the development of the final draft	Wrote the paper	Writing - Original Draft	YES
5488370	28655320	BFN	1	Coordinated and drafted the manuscript	Coordinated and drafted the manuscript	Wrote the paper	Project administration|Writing - Original Draft	YES
5488370	28655320	CRP	1	Coordinated and drafted the manuscript	Coordinated and drafted the manuscript	Wrote the paper	Project administration|Writing - Original Draft	YES
5488370	28655320	DJM	1	Coordinated and drafted the manuscript	Coordinated and drafted the manuscript	Wrote the paper	Project administration|Writing - Original Draft	YES
5488370	28655320	RDH	1	Coordinated and drafted the manuscript	Coordinated and drafted the manuscript	Wrote the paper	Project administration|Writing - Original Draft	YES
6338103	30657644	Carolyn F. Williams	2	participated in calls and meetings of the treat all consensus statement working group to define and direct the consensus development process|critically reviewed drafts and contributed substantive content to the consensus statement manuscript	participated in calls and meetings of the treat all consensus statement working group to define and direct the consensus development process	Analyzed the data	Formal analysis	YES
6338103	30657644	Carolyn F. Williams	2	participated in calls and meetings of the treat all consensus statement working group to define and direct the consensus development process|critically reviewed drafts and contributed substantive content to the consensus statement manuscript	critically reviewed drafts and contributed substantive content to the consensus statement manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
6338103	30657644	Constantin Yiannoutsos	2	participated in calls and meetings of the treat all consensus statement working group to define and direct the consensus development process	participated in calls and meetings of the treat all consensus statement working group to define and direct the consensus development process	Analyzed the data	Formal analysis	YES
6338103	30657644	Denis Nash	2	drafted the consensus statement manuscript, drawing on the background document prepared for the kigali meeting	drafted the consensus statement manuscript, drawing on the background document prepared for the kigali meeting	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6338103	30657644	Ellen Brazier	2	coordinated all rounds of the delphi process|drafted the consensus statement manuscript, drawing on the background document prepared for the kigali meeting	coordinated all rounds of the delphi process	-	Project administration	YES
6338103	30657644	Ellen Brazier	2	coordinated all rounds of the delphi process|drafted the consensus statement manuscript, drawing on the background document prepared for the kigali meeting	drafted the consensus statement manuscript, drawing on the background document prepared for the kigali meeting	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6338103	30657644	Gilles Wandeler	2	participated in calls and meetings of the treat all consensus statement working group to define and direct the consensus development process|critically reviewed drafts and contributed substantive content to the consensus statement manuscript	participated in calls and meetings of the treat all consensus statement working group to define and direct the consensus development process	Analyzed the data	Formal analysis	YES
6338103	30657644	Gilles Wandeler	2	participated in calls and meetings of the treat all consensus statement working group to define and direct the consensus development process|critically reviewed drafts and contributed substantive content to the consensus statement manuscript	critically reviewed drafts and contributed substantive content to the consensus statement manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
6338103	30657644	Kara Wools-Kaloustian	2	participated in calls and meetings of the treat all consensus statement working group to define and direct the consensus development process|critically reviewed drafts and contributed substantive content to the consensus statement manuscript	participated in calls and meetings of the treat all consensus statement working group to define and direct the consensus development process	Analyzed the data	Formal analysis	YES
6338103	30657644	Kara Wools-Kaloustian	2	participated in calls and meetings of the treat all consensus statement working group to define and direct the consensus development process|critically reviewed drafts and contributed substantive content to the consensus statement manuscript	critically reviewed drafts and contributed substantive content to the consensus statement manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
6338103	30657644	Marcel Yotebieng	2	participated in calls and meetings of the treat all consensus statement working group to define and direct the consensus development process|drafted the consensus statement manuscript, drawing on the background document prepared for the kigali meeting|critically reviewed drafts and contributed substantive content to the consensus statement manuscript	participated in calls and meetings of the treat all consensus statement working group to define and direct the consensus development process	Analyzed the data	Formal analysis	YES
6338103	30657644	Marcel Yotebieng	2	participated in calls and meetings of the treat all consensus statement working group to define and direct the consensus development process|drafted the consensus statement manuscript, drawing on the background document prepared for the kigali meeting|critically reviewed drafts and contributed substantive content to the consensus statement manuscript	drafted the consensus statement manuscript, drawing on the background document prepared for the kigali meeting	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6338103	30657644	Marcel Yotebieng	2	participated in calls and meetings of the treat all consensus statement working group to define and direct the consensus development process|drafted the consensus statement manuscript, drawing on the background document prepared for the kigali meeting|critically reviewed drafts and contributed substantive content to the consensus statement manuscript	critically reviewed drafts and contributed substantive content to the consensus statement manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
6338103	30657644	Rachel C. Vreeman	2	participated in calls and meetings of the treat all consensus statement working group to define and direct the consensus development process	participated in calls and meetings of the treat all consensus statement working group to define and direct the consensus development process	Analyzed the data	Formal analysis	YES
6338103	30657644	Radhika Wikramanayake	2	participated in calls and meetings of the treat all consensus statement working group to define and direct the consensus development process	participated in calls and meetings of the treat all consensus statement working group to define and direct the consensus development process	Analyzed the data	Formal analysis	YES
4411037	25915545	ASW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411037	25915545	ASW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411037	25915545	ASW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411037	25915545	CID	PLoS5	Performed the experiments|Edited the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4411037	25915545	CID	PLoS5	Performed the experiments|Edited the manuscript	Edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
4411037	25915545	DMM	PLoS5	Conceived and designed the experiments|Analyzed the data|Edited the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411037	25915545	DMM	PLoS5	Conceived and designed the experiments|Analyzed the data|Edited the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4411037	25915545	DMM	PLoS5	Conceived and designed the experiments|Analyzed the data|Edited the manuscript	Edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
4411037	25915545	KGS	PLoS5	Performed the experiments|Edited the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4411037	25915545	KGS	PLoS5	Performed the experiments|Edited the manuscript	Edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
4411037	25915545	LAH	PLoS5	Performed the experiments|Edited the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4411037	25915545	LAH	PLoS5	Performed the experiments|Edited the manuscript	Edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
4411037	25915545	MMA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411037	25915545	MMA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411037	25915545	MMA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411037	25915545	MMA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1804257	17330142	JC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1804257	17330142	JC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1804257	17330142	JC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1804257	17330142	PU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1804257	17330142	PU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1804257	17330142	PU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1804257	17330142	PU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5488377	28655295	DMC	2	conceived and directed the study, participated in its design and coordination and helped to draft the manuscript	conceived and directed the study, participated in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Supervision|Writing - Original Draft	YES
5488377	28655295	FP	2	designed the experiment, carried out the bioinformatics analyses, and drafted the manuscript	designed the experiment, carried out the bioinformatics analyses, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5488377	28655295	HLL	2	participated in the design of the experiments and helped to draft the manuscript	participated in the design of the experiments and helped to draft the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5488377	28655295	MW	2	participated in the design of the study, implemented the software, and helped to draft the manuscript	participated in the design of the study, implemented the software, and helped to draft the manuscript	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Methodology|Software|Writing - Original Draft	YES
5488377	28655295	WYC	2	implemented the software, and helped to handle figures and tables	implemented the software, and helped to handle figures and tables	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software|Visualization	YES
5488377	28655295	YW	2	participated in the design of the study, implemented the software, and drafted the manuscript	participated in the design of the study, implemented the software, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Methodology|Software|Writing - Original Draft	YES
5488377	28655295	YX	2	as the correspondence author, provided financial support for the article and designed the way and frame of this study	as the correspondence author, provided financial support for the article and designed the way and frame of this study	Conceived and designed the experiments	Funding acquisition|Methodology	YES
5655116	29104584	AO	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5655116	29104584	All authors	PLoS52	approved the final manuscript	approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5655116	29104584	CC	PLoS52	supervised experiments	supervised experiments	-	Supervision	YES
5655116	29104584	CM	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5655116	29104584	CP	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5655116	29104584	DP	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5655116	29104584	ES	PLoS52	supervised experiments	supervised experiments	-	Supervision	YES
5655116	29104584	FP	PLoS52	supervised experiments	supervised experiments	-	Supervision	YES
5655116	29104584	JS	PLoS52	conceived, designed the study and wrote the manuscript|states that the process met the standards of a fair and objective review	conceived, designed the study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
5655116	29104584	JS	PLoS52	conceived, designed the study and wrote the manuscript|states that the process met the standards of a fair and objective review	states that the process met the standards of a fair and objective review	Analyzed the data	Formal analysis	YES
5655116	29104584	MC	PLoS52	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5655116	29104584	ND	PLoS52	performed the experiments|took part in writing the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5655116	29104584	ND	PLoS52	performed the experiments|took part in writing the manuscript	took part in writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5655116	29104584	PC	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5655116	29104584	The authors	PLoS52	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	Performed the experiments	Investigation	YES
4411043	25915782	CS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411043	25915782	CS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411043	25915782	FG	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411043	25915782	FG	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411043	25915782	FG	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411043	25915782	HM	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4411043	25915782	HV	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411043	25915782	JQ	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4411043	25915782	JQ	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4411043	25915782	KT	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4411043	25915782	KT	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4411043	25915782	MAV	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411043	25915782	SD	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4411043	25915782	SD	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4411043	25915782	VS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411043	25915782	VS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3222304	21906343	AP	2	participated in the design of the electron microscopy studies	participated in the design of the electron microscopy studies	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3222304	21906343	CA	2	conceived the study, carried out the design and the execution of the biodegradation experiments and executed the electron microscopy studies	conceived the study, carried out the design and the execution of the biodegradation experiments and executed the electron microscopy studies	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
3222304	21906343	FL	2	participated in the design and coordination of the study	participated in the design and coordination of the study	Conceived and designed the experiments	Methodology|Project administration	YES
6338297	30657639	CT	PLoS52	performed the research|analysed the data|contributed to the draft	performed the research	Performed the experiments	Investigation	YES
6338297	30657639	CT	PLoS52	performed the research|analysed the data|contributed to the draft	analysed the data	Analyzed the data	Formal analysis	YES
6338297	30657639	CT	PLoS52	performed the research|analysed the data|contributed to the draft	contributed to the draft	Wrote the paper	Writing - Original Draft	YES
6338297	30657639	ET	PLoS52	performed the research|analysed the data|wrote the paper	performed the research	Performed the experiments	Investigation	YES
6338297	30657639	ET	PLoS52	performed the research|analysed the data|wrote the paper	analysed the data	Analyzed the data	Formal analysis	YES
6338297	30657639	ET	PLoS52	performed the research|analysed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6338297	30657639	JC	PLoS52	designed the research study|performed the research|analysed the data|contributed to the draft	designed the research study	Conceived and designed the experiments	Methodology	YES
6338297	30657639	JC	PLoS52	designed the research study|performed the research|analysed the data|contributed to the draft	performed the research	Performed the experiments	Investigation	YES
6338297	30657639	JC	PLoS52	designed the research study|performed the research|analysed the data|contributed to the draft	analysed the data	Analyzed the data	Formal analysis	YES
6338297	30657639	JC	PLoS52	designed the research study|performed the research|analysed the data|contributed to the draft	contributed to the draft	Wrote the paper	Writing - Original Draft	YES
6338297	30657639	MV	PLoS52	analysed the data|wrote the paper	analysed the data	Analyzed the data	Formal analysis	YES
6338297	30657639	MV	PLoS52	analysed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5179934	27895259	A.H.	2	collaborated on the synchrotron powder diffraction experiments	collaborated on the synchrotron powder diffraction experiments	Performed the experiments	Investigation	YES
5179934	27895259	I.J.V.-Y.	2	carried out all experimental work	carried out all experimental work	Performed the experiments	Investigation	YES
5179934	27895259	L.B.	2	directed the research|drafted the manuscript	directed the research	-	Supervision	YES
5179934	27895259	L.B.	2	directed the research|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5179934	27895259	R.S.	2	carried out all experimental work|drafted the manuscript	carried out all experimental work	Performed the experiments	Investigation	YES
5179934	27895259	R.S.	2	carried out all experimental work|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5488378	28655355	All of the authors	PLoS52	assisted in writing the manuscript, discussed the results, and commented on the manuscript	assisted in writing the manuscript, discussed the results, and commented on the manuscript	Wrote the paper	Writing - Original Draft	YES
5488378	28655355	DL	PLoS52	conducted the experiments and analyzed the data	conducted the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5488378	28655355	KL	PLoS52	conducted the experiments and analyzed the data	conducted the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5488378	28655355	KT	PLoS52	conceived and designed the experiments|conducted the experiments and analyzed the data	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5488378	28655355	KT	PLoS52	conceived and designed the experiments|conducted the experiments and analyzed the data	conducted the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5488378	28655355	NJ	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5488378	28655355	QZ	PLoS52	conducted the experiments and analyzed the data	conducted the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5488378	28655355	YH	PLoS52	conducted the experiments and analyzed the data	conducted the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5488378	28655355	YY	PLoS52	conducted the experiments and analyzed the data	conducted the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
1805684	17356691	AA	PLoS5	Was involved in study design, data analysis and review of the manuscript	Was involved in study design, data analysis and review of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
1805684	17356691	DS	PLoS5	Was involved in study design, data analysis and review of the manuscript	Was involved in study design, data analysis and review of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
1805684	17356691	KA	PLoS5	Designed and conducted the study and had equal participation	Designed and conducted the study and had equal participation	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
1805684	17356691	MA	PLoS5	Designed and conducted the study and had equal participation	Designed and conducted the study and had equal participation	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
1805684	17356691	MI	PLoS5	Was involved in study design, data analysis and review of the manuscript	Was involved in study design, data analysis and review of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
1805684	17356691	PF	PLoS5	Overall supervisor of the project, helped at all steps	Overall supervisor of the project, helped at all steps	-	Supervision	YES
1805684	17356691	RS	PLoS5	Designed and conducted the study and had equal participation	Designed and conducted the study and had equal participation	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
1805684	17356691	SH	PLoS5	Analyzed the data|Wrote the paper|Designed and conducted the study and had equal participation	Analyzed the data	Analyzed the data	Formal analysis	YES
1805684	17356691	SH	PLoS5	Analyzed the data|Wrote the paper|Designed and conducted the study and had equal participation	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1805684	17356691	SH	PLoS5	Analyzed the data|Wrote the paper|Designed and conducted the study and had equal participation	Designed and conducted the study and had equal participation	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
1805684	17356691	UA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1805684	17356691	UA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1805684	17356691	UA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5655848	29104577	HC	2	provided revisions, and all three authors approved this mini review for publication	provided revisions, and all three authors approved this mini review for publication	Wrote the paper	Writing - Review & Editing	YES
5655848	29104577	SC	2	provided revisions, and all three authors approved this mini review for publication	provided revisions, and all three authors approved this mini review for publication	Wrote the paper	Writing - Review & Editing	YES
5655848	29104577	TW	2	collected literature and wrote the paper	collected literature and wrote the paper	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4411044	25915206	HP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411044	25915206	HP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411044	25915206	HP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411044	25915206	HP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411044	25915206	JL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4411044	25915206	JL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4411044	25915206	JL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411044	25915206	JM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411044	25915206	JM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411044	25915206	JM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411044	25915206	TY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411044	25915206	TY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411044	25915206	TY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411044	25915206	TY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411044	25915206	TY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411044	25915206	YB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411044	25915206	YB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411044	25915206	YB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6340053	30663278	AA	2	coordinated the icona foundation, conceived and supervised the study and finalized the draft of the manuscript	coordinated the icona foundation, conceived and supervised the study and finalized the draft of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Project administration|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
6340053	30663278	AC	2	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
6340053	30663278	ACL	2	contributed to the design of the study, was the main responsible person for data analysis and contributed to the article drafting	contributed to the design of the study, was the main responsible person for data analysis and contributed to the article drafting	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Original Draft	YES
6340053	30663278	ADL	2	contributed to data interpretation and article drafting	contributed to data interpretation and article drafting	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6340053	30663278	AM	2	designed the study, wrote the first draft of the manuscript and referred to appropriate literature	designed the study, wrote the first draft of the manuscript and referred to appropriate literature	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
6340053	30663278	AT	2	was the main responsible person for the data collection and contributed to data interpretation and article drafting	was the main responsible person for the data collection and contributed to data interpretation and article drafting	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6340053	30663278	AdAM	2	coordinated the icona foundation, conceived and supervised the study and finalized the draft of the manuscript	coordinated the icona foundation, conceived and supervised the study and finalized the draft of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Project administration|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
6340053	30663278	All authors	2	agreed with final article submission	agreed with final article submission	-	-	NO
6340053	30663278	FCS	2	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
6340053	30663278	FM	2	contributed to data interpretation and article drafting	contributed to data interpretation and article drafting	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6340053	30663278	FV	2	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
6340053	30663278	GM	2	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
6340053	30663278	SR	2	contributed to data interpretation and article drafting	contributed to data interpretation and article drafting	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
1805685	17356694	CC	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1805685	17356694	MP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1805685	17356694	MP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1805685	17356694	MP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1805685	17356694	SS	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1805685	17356694	SS	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5490172	28662628	IK	2	contributed to the analysis	contributed to the analysis	-	-	NO
5490172	28662628	JDR	2	contributed to the analysis	contributed to the analysis	-	-	NO
5490172	28662628	JF	2	contributed to the analysis	contributed to the analysis	-	-	NO
5490172	28662628	MB	2	conceived and designed research|performed research|contributed to the analysis|drafted the manuscript	conceived and designed research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5490172	28662628	MB	2	conceived and designed research|performed research|contributed to the analysis|drafted the manuscript	performed research	Performed the experiments	Investigation	YES
5490172	28662628	MB	2	conceived and designed research|performed research|contributed to the analysis|drafted the manuscript	contributed to the analysis	-	-	NO
5490172	28662628	MB	2	conceived and designed research|performed research|contributed to the analysis|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5490172	28662628	MM	2	conceived and designed research|drafted the manuscript	conceived and designed research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5490172	28662628	MM	2	conceived and designed research|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5490172	28662628	MMK	2	contributed to the analysis	contributed to the analysis	-	-	NO
5490172	28662628	PC	2	conceived and designed research|drafted the manuscript	conceived and designed research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5490172	28662628	PC	2	conceived and designed research|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5655971	29104579	EO	2	conceived and designed the research, performed the experiments, and wrote the manuscript	conceived and designed the research, performed the experiments, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Writing - Original Draft	YES
5655971	29104579	GH	2	conceived and designed the research, performed the experiments, and wrote the manuscript	conceived and designed the research, performed the experiments, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Writing - Original Draft	YES
5655971	29104579	IP	2	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5655971	29104579	J-YZ	2	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5655971	29104579	JK	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5655971	29104579	SK	2	conceived and designed the research, performed the experiments, and wrote the manuscript	conceived and designed the research, performed the experiments, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Writing - Original Draft	YES
5655971	29104579	SL	2	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5655971	29104579	TN	2	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6341973	30667175	BW	2	drafted, read and reviewed final version of letter	drafted, read and reviewed final version of letter	Wrote the paper	Writing - Original Draft	YES
4411045	25915640	BDS	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411045	25915640	HPP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411045	25915640	HPP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411045	25915640	HPP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411045	25915640	HPP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411045	25915640	XGZ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411045	25915640	XGZ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411045	25915640	XGZ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411045	25915640	XWY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411045	25915640	XWY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4411045	25915640	XWY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1805686	17356695	BI	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1805686	17356695	BI	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1805686	17356695	BI	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1805686	17356695	DA	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1805686	17356695	DA	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1805686	17356695	JC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1805686	17356695	JC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1805686	17356695	JC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1805686	17356695	JF	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1805686	17356695	JF	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1805686	17356695	JF	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1805686	17356695	LG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1805686	17356695	LG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1805686	17356695	LG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1805686	17356695	MO	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1805686	17356695	MO	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1805686	17356695	MO	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1805686	17356695	MO	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1805686	17356695	MS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1805686	17356695	MS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1805686	17356695	MS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1805686	17356695	MT	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1805686	17356695	MT	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1805686	17356695	PA	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1805686	17356695	PA	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1805686	17356695	VL	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1805686	17356695	VL	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5903369	29719691	D.Z.Z.	2	helped with manuscript writing	helped with manuscript writing	Wrote the paper	Writing - Original Draft	YES
5903369	29719691	F.G.W.	2	helped to guide the potential clinical use	helped to guide the potential clinical use	-	-	NO
5903369	29719691	L.C.	2	helped with manuscript writing	helped with manuscript writing	Wrote the paper	Writing - Original Draft	YES
5903369	29719691	L.R.G.	2	participated in the animal experiments	participated in the animal experiments	Performed the experiments	Investigation	YES
5903369	29719691	Q.X.	2	designed the research, conducted the majority of the experiments, analyzed the data, and wrote the manuscript	designed the research, conducted the majority of the experiments, analyzed the data, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5903369	29719691	U.G.	2	helped with manuscript writing	helped with manuscript writing	Wrote the paper	Writing - Original Draft	YES
5903369	29719691	W.G.L.	2	helped with manuscript writing	helped with manuscript writing	Wrote the paper	Writing - Original Draft	YES
5903369	29719691	W.W.	2	led in the design and synthesis of the macromers and hydrogels, and the animal experiments	led in the design and synthesis of the macromers and hydrogels, and the animal experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5903369	29719691	W.X.W.	2	came up with the original concepts and led the project|supervised the research	came up with the original concepts and led the project	Conceived and designed the experiments	Conceptualization	YES
5903369	29719691	W.X.W.	2	came up with the original concepts and led the project|supervised the research	supervised the research	-	Supervision	YES
5903369	29719691	Y.X.D.	2	helped with the optimization of the animal model	helped with the optimization of the animal model	Performed the experiments	Methodology	YES
5247477	28069764	All authors	2	contributed equally to this work	contributed equally to this work	-	-	NO
6341974	30667176	JJO	2	drafted the initial version of the letter|circulated the finalized letter for approval from all authors prior to submission	drafted the initial version of the letter	Wrote the paper	Writing - Original Draft	YES
6341974	30667176	JJO	2	drafted the initial version of the letter|circulated the finalized letter for approval from all authors prior to submission	circulated the finalized letter for approval from all authors prior to submission	-	-	NO
6341974	30667176	TBH	2	drafted the initial version of the letter	drafted the initial version of the letter	Wrote the paper	Writing - Original Draft	YES
5490193	28659179	AAK	2	assembled the wfol genome including initial annotation of the wfol genome	assembled the wfol genome including initial annotation of the wfol genome	Analyzed the data	Data curation|Formal analysis	YES
5490193	28659179	AFV	2	conceived, designed, coordinated the study and drafted the manuscript|performed the assembly of the genome|performed further scaffolding of the initial genome assembly, performed gene annotation and set up the genome portal	conceived, designed, coordinated the study and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
5490193	28659179	AFV	2	conceived, designed, coordinated the study and drafted the manuscript|performed the assembly of the genome|performed further scaffolding of the initial genome assembly, performed gene annotation and set up the genome portal	performed the assembly of the genome	Performed the experiments	Investigation	YES
5490193	28659179	AFV	2	conceived, designed, coordinated the study and drafted the manuscript|performed the assembly of the genome|performed further scaffolding of the initial genome assembly, performed gene annotation and set up the genome portal	performed further scaffolding of the initial genome assembly, performed gene annotation and set up the genome portal	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation|Methodology	YES
5490193	28659179	All authors	2	provided input and comments on subsequent revisions of the manuscript and approved the final version	provided input and comments on subsequent revisions of the manuscript and approved the final version	Wrote the paper	Writing - Review & Editing	YES
5490193	28659179	CAMvG	2	assisted in the analysis of gene family expansions involved in stress response	assisted in the analysis of gene family expansions involved in stress response	-	-	NO
5490193	28659179	DR	2	conceived, designed, coordinated the study and drafted the manuscript|assisted in interpretation of the go-enriched annotated gene families|performed hox gene cluster analysis and microrna analysis	conceived, designed, coordinated the study and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
5490193	28659179	DR	2	conceived, designed, coordinated the study and drafted the manuscript|assisted in interpretation of the go-enriched annotated gene families|performed hox gene cluster analysis and microrna analysis	assisted in interpretation of the go-enriched annotated gene families	Analyzed the data	Formal analysis	YES
5490193	28659179	DR	2	conceived, designed, coordinated the study and drafted the manuscript|assisted in interpretation of the go-enriched annotated gene families|performed hox gene cluster analysis and microrna analysis	performed hox gene cluster analysis and microrna analysis	Performed the experiments	Investigation	YES
5490193	28659179	GO	2	enrichment of the hgt gene set	enrichment of the hgt gene set	-	-	NO
5490193	28659179	JE	2	assembled the wfol genome including initial annotation of the wfol genome	assembled the wfol genome including initial annotation of the wfol genome	Analyzed the data	Data curation|Formal analysis	YES
5490193	28659179	MFLD	2	performed further scaffolding of the initial genome assembly, performed gene annotation and set up the genome portal	performed further scaffolding of the initial genome assembly, performed gene annotation and set up the genome portal	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation|Methodology	YES
5490193	28659179	NMvS	2	conceived, designed, coordinated the study and drafted the manuscript	conceived, designed, coordinated the study and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
5490193	28659179	SS	2	performed further scaffolding of the initial genome assembly, performed gene annotation and set up the genome portal	performed further scaffolding of the initial genome assembly, performed gene annotation and set up the genome portal	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation|Methodology	YES
5490193	28659179	SYA	2	performed the assembly of the genome	performed the assembly of the genome	Performed the experiments	Investigation	YES
4411046	25915897	LZ	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411046	25915897	LZ	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411046	25915897	MZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411046	25915897	MZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411046	25915897	MZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411046	25915897	MZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411046	25915897	MZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411046	25915897	ST	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411046	25915897	ST	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411046	25915897	ST	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5660262	29109733	DS	2	provided feedback and oversaw progression of the manuscript	provided feedback and oversaw progression of the manuscript	-	Supervision	YES
5660262	29109733	GI	2	gathered literature and prepared the manuscript	gathered literature and prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
1805687	17356696	AF	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1805687	17356696	JO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1805687	17356696	JO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1805687	17356696	JO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1805687	17356696	JO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1805687	17356696	JO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1805687	17356696	KT	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1805687	17356696	KT	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1805687	17356696	RK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1805687	17356696	RK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1805687	17356696	RK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1805687	17356696	RK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1805687	17356696	RK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5247484	28069771	All authors	2	contributed equally to the paper	contributed equally to the paper	-	-	NO
6344908	30675984	AV	2	participated in data analysis and revised the manuscript	participated in data analysis and revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
6344908	30675984	EAB	2	were involved in designing and conducting the study and revised the manuscript	were involved in designing and conducting the study and revised the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
6344908	30675984	FS	2	were involved in study design, overseeing data collection, analysis and revision of the manuscript	were involved in study design, overseeing data collection, analysis and revision of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Supervision|Writing - Review & Editing	YES
6344908	30675984	GM	2	were involved in study design, overseeing data collection, analysis and revision of the manuscript	were involved in study design, overseeing data collection, analysis and revision of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Supervision|Writing - Review & Editing	YES
6344908	30675984	JKE	2	designed the study, oversaw data collection, performed the analysis and wrote the manuscript	designed the study, oversaw data collection, performed the analysis and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Supervision|Writing - Original Draft	YES
6344908	30675984	JTO	2	were involved in designing and conducting the study and revised the manuscript	were involved in designing and conducting the study and revised the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
6344908	30675984	MM	2	were involved in study design, overseeing data collection, analysis and revision of the manuscript	were involved in study design, overseeing data collection, analysis and revision of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Supervision|Writing - Review & Editing	YES
6344908	30675984	PA	2	were involved in designing and conducting the study and revised the manuscript	were involved in designing and conducting the study and revised the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
6344908	30675984	SS	2	was involved in study design and revised the manuscript	was involved in study design and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
1805688	17356697	JB	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1805688	17356697	JB	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1805688	17356697	SS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1805688	17356697	SS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1805688	17356697	SS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1805688	17356697	SS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5490208	28659170	AP	1	Conceived the study|Generated the data|Performed the analyses|Wrote the manuscript	Conceived the study	Conceived and designed the experiments	Conceptualization	YES
5490208	28659170	AP	1	Conceived the study|Generated the data|Performed the analyses|Wrote the manuscript	Generated the data	Performed the experiments	Investigation	YES
5490208	28659170	AP	1	Conceived the study|Generated the data|Performed the analyses|Wrote the manuscript	Performed the analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5490208	28659170	AP	1	Conceived the study|Generated the data|Performed the analyses|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5490208	28659170	AS	1	Made substantial contributions to acquisition of data	Made substantial contributions to acquisition of data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5490208	28659170	CKK	1	Generated the data|Made substantial contributions to acquisition of data	Generated the data	Performed the experiments	Investigation	YES
5490208	28659170	CKK	1	Generated the data|Made substantial contributions to acquisition of data	Made substantial contributions to acquisition of data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5490208	28659170	PGA	1	Generated the data|Made substantial contributions to acquisition of data	Generated the data	Performed the experiments	Investigation	YES
5490208	28659170	PGA	1	Generated the data|Made substantial contributions to acquisition of data	Made substantial contributions to acquisition of data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5490208	28659170	PK	1	Generated the data|Performed the analyses|Wrote the manuscript	Generated the data	Performed the experiments	Investigation	YES
5490208	28659170	PK	1	Generated the data|Performed the analyses|Wrote the manuscript	Performed the analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5490208	28659170	PK	1	Generated the data|Performed the analyses|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5346219	28265024	J.M.	2	jointly planned out of the optimization framework and carried out final editing	jointly planned out of the optimization framework and carried out final editing	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Review & Editing	YES
5346219	28265024	W.M.	2	performed the implementations discussed in this paper, ran the simulations and drafted the manuscript|jointly planned out of the optimization framework and carried out final editing	performed the implementations discussed in this paper, ran the simulations and drafted the manuscript	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5346219	28265024	W.M.	2	performed the implementations discussed in this paper, ran the simulations and drafted the manuscript|jointly planned out of the optimization framework and carried out final editing	jointly planned out of the optimization framework and carried out final editing	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Review & Editing	YES
5660708	29114254	CL	2	commented and revised the manuscript	commented and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5660708	29114254	DM	2	commented and revised the manuscript	commented and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5660708	29114254	GY	2	conceived the ideas and developed the draft	conceived the ideas and developed the draft	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5660708	29114254	HL	2	conceived the ideas and developed the draft	conceived the ideas and developed the draft	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5660708	29114254	HW	2	commented and revised the manuscript	commented and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5660708	29114254	JH	2	commented and revised the manuscript	commented and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5660708	29114254	YW	2	commented and revised the manuscript	commented and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5660708	29114254	ZL	2	commented and revised the manuscript	commented and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4411048	25915049	BK	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4411048	25915049	ED	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4411048	25915049	ED	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4411048	25915049	IR	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411048	25915049	IR	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411048	25915049	JC	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411048	25915049	JC	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411048	25915049	MB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411048	25915049	MB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411048	25915049	MB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411048	25915049	MC	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4411048	25915049	N. Papandreou	PLoS5	Performed the experiments|Designed the mir software	Performed the experiments	Performed the experiments	Investigation	YES
4411048	25915049	N. Papandreou	PLoS5	Performed the experiments|Designed the mir software	Designed the mir software	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
4411048	25915049	N. Prudhomme	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
3222310	21906340	AS	2	participated in the design of the study, commented on the manuscript and supervised the ph	participated in the design of the study, commented on the manuscript and supervised the ph	Conceived and designed the experiments	Methodology|Supervision	YES
3222310	21906340	BAK	2	carried out the enzyme purification and biochemical experiments and drafted the manuscript|from which large parts of this study originated	carried out the enzyme purification and biochemical experiments and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3222310	21906340	BAK	2	carried out the enzyme purification and biochemical experiments and drafted the manuscript|from which large parts of this study originated	from which large parts of this study originated	Conceived and designed the experiments	Conceptualization	YES
3222310	21906340	CV	2	performed the genome sequencing and assembly and provided nucleotide sequence data	performed the genome sequencing and assembly and provided nucleotide sequence data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
3222310	21906340	DB	2	carried out protein analysis and identification	carried out protein analysis and identification	Performed the experiments	Investigation	YES
3222310	21906340	ER	2	carried out protein analysis and identification	carried out protein analysis and identification	Performed the experiments	Investigation	YES
3222310	21906340	FLPG	2	elaborated gc-ms data, conceived fragmentation patterns and commented on the manuscript	elaborated gc-ms data, conceived fragmentation patterns and commented on the manuscript	Conceived and designed the experiments	Conceptualization	YES
3222310	21906340	HPEK	2	participated in the design of the study and commented on the manuscript	participated in the design of the study and commented on the manuscript	Conceived and designed the experiments	Methodology	YES
3222310	21906340	JF	2	performed the genome sequencing and assembly and provided nucleotide sequence data	performed the genome sequencing and assembly and provided nucleotide sequence data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
3222310	21906340	ML	2	performed ipc-ms analyses	performed ipc-ms analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3222310	21906340	PFXC	2	participated in the design of the study, commented on the manuscript and supervised the ph	participated in the design of the study, commented on the manuscript and supervised the ph	Conceived and designed the experiments	Methodology|Supervision	YES
6351701	30697944	AA	2	contributed to the concept development|contributed data for the analysis	contributed to the concept development	Conceived and designed the experiments	Conceptualization	YES
6351701	30697944	AA	2	contributed to the concept development|contributed data for the analysis	contributed data for the analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6351701	30697944	AJ	2	contributed to the concept development|performed the statistical analysis	contributed to the concept development	Conceived and designed the experiments	Conceptualization	YES
6351701	30697944	AJ	2	contributed to the concept development|performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
6351701	30697944	AK	2	contributed data for the analysis	contributed data for the analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6351701	30697944	All authors	2	commented on the draft manuscript and approved of the final manuscript	commented on the draft manuscript and approved of the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6351701	30697944	BS	2	contributed data for the analysis	contributed data for the analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6351701	30697944	CDD	2	contributed data for the analysis	contributed data for the analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6351701	30697944	EY	2	contributed data for the analysis	contributed data for the analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6351701	30697944	FZ	2	contributed data for the analysis	contributed data for the analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6351701	30697944	JT	2	contributed data for the analysis	contributed data for the analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6351701	30697944	JYC	2	contributed data for the analysis	contributed data for the analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6351701	30697944	KVN	2	contributed data for the analysis	contributed data for the analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6351701	30697944	LPS	2	contributed data for the analysis	contributed data for the analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6351701	30697944	MPL	2	contributed data for the analysis	contributed data for the analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6351701	30697944	NK	2	contributed data for the analysis	contributed data for the analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6351701	30697944	OTN	2	contributed data for the analysis	contributed data for the analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6351701	30697944	RC	2	contributed data for the analysis	contributed data for the analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6351701	30697944	RD	2	contributed data for the analysis	contributed data for the analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6351701	30697944	SK	2	contributed data for the analysis|contributed data for the analysis	contributed data for the analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6351701	30697944	SK	2	contributed data for the analysis|contributed data for the analysis	contributed data for the analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6351701	30697944	SP	2	contributed data for the analysis	contributed data for the analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6351701	30697944	TPM	2	contributed data for the analysis	contributed data for the analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6351701	30697944	WH	2	contributed to the concept development|wrote the first draft of the manuscript	contributed to the concept development	Conceived and designed the experiments	Conceptualization	YES
6351701	30697944	WH	2	contributed to the concept development|wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
6351701	30697944	WWW	2	contributed data for the analysis	contributed data for the analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
1805689	17372625	CC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1805689	17372625	CC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1805689	17372625	CC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1805689	17372625	CC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5660721	29114256	All the authors	PLoS52	participated in the revision of the manuscript	participated in the revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5660721	29114256	CH	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5660721	29114256	J-GC	PLoS52	conceived the study and designed the experiments	conceived the study and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5660721	29114256	KZ	PLoS52	performed the experiments|analyzed the data|drafted the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5660721	29114256	KZ	PLoS52	performed the experiments|analyzed the data|drafted the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5660721	29114256	KZ	PLoS52	performed the experiments|analyzed the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5660721	29114256	NZ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5660721	29114256	QJ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5660721	29114256	SW	PLoS52	conceived the study and designed the experiments|analyzed the data|drafted the manuscript	conceived the study and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5660721	29114256	SW	PLoS52	conceived the study and designed the experiments|analyzed the data|drafted the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5660721	29114256	SW	PLoS52	conceived the study and designed the experiments|analyzed the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5660721	29114256	XW	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5660721	29114256	YW	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
3222312	21906347	ASV	2	participated in the design of the study and analysis of the data|wrote the manuscript and all authors participated in commenting and revising it	participated in the design of the study and analysis of the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
3222312	21906347	ASV	2	participated in the design of the study and analysis of the data|wrote the manuscript and all authors participated in commenting and revising it	wrote the manuscript and all authors participated in commenting and revising it	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3222312	21906347	All authors	2	contributed to the scientific discussion throughout the work and have read and approved the final manuscript	contributed to the scientific discussion throughout the work and have read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
3222312	21906347	JK	2	participated in the design of the study and analysis of the data	participated in the design of the study and analysis of the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
3222312	21906347	NK	2	participated in the design of the study, performed the experimental work and data interpretation	participated in the design of the study, performed the experimental work and data interpretation	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
3222312	21906347	TT	2	participated in the design of the study and analysis of the data	participated in the design of the study and analysis of the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
3222312	21906347	WR	2	participated in bacterial screening	participated in bacterial screening	Performed the experiments	Investigation	YES
5490213	28659188	RKS	2	has edited the manuscript and supervised the work	has edited the manuscript and supervised the work	Wrote the paper	Supervision|Writing - Review & Editing	YES
5490213	28659188	SU	2	has helped gj in transcriptome analysis	has helped gj in transcriptome analysis	-	-	NO
4411049	25915523	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411049	25915523	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411049	25915523	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411049	25915523	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411049	25915523	LG-C	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411049	25915523	MC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411049	25915523	MC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411049	25915523	MC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411049	25915523	MC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411049	25915523	MS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411049	25915523	MS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411049	25915523	MS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411049	25915523	MS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1805814	17332843	AA	1	Designed the study|Peformed further statistical analyses|Contributed to the interpretation of the findings and formulation of the report|Contributed to revision of the manuscript	Designed the study	Conceived and designed the experiments	Methodology	YES
1805814	17332843	AA	1	Designed the study|Peformed further statistical analyses|Contributed to the interpretation of the findings and formulation of the report|Contributed to revision of the manuscript	Peformed further statistical analyses	Analyzed the data	Formal analysis	YES
1805814	17332843	AA	1	Designed the study|Peformed further statistical analyses|Contributed to the interpretation of the findings and formulation of the report|Contributed to revision of the manuscript	Contributed to the interpretation of the findings and formulation of the report	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
1805814	17332843	AA	1	Designed the study|Peformed further statistical analyses|Contributed to the interpretation of the findings and formulation of the report|Contributed to revision of the manuscript	Contributed to revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
1805814	17332843	AR	1	Contributed to the interpretation of the findings and formulation of the report|Contributed to revision of the manuscript	Contributed to the interpretation of the findings and formulation of the report	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
1805814	17332843	AR	1	Contributed to the interpretation of the findings and formulation of the report|Contributed to revision of the manuscript	Contributed to revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
1805814	17332843	AV	1	Contributed to the interpretation of the findings and formulation of the report|Contributed to revision of the manuscript	Contributed to the interpretation of the findings and formulation of the report	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
1805814	17332843	AV	1	Contributed to the interpretation of the findings and formulation of the report|Contributed to revision of the manuscript	Contributed to revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
1805814	17332843	HH	1	Peformed further statistical analyses|Contributed to the interpretation of the findings and formulation of the report|Contributed to revision of the manuscript	Peformed further statistical analyses	Analyzed the data	Formal analysis	YES
1805814	17332843	HH	1	Peformed further statistical analyses|Contributed to the interpretation of the findings and formulation of the report|Contributed to revision of the manuscript	Contributed to the interpretation of the findings and formulation of the report	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
1805814	17332843	HH	1	Peformed further statistical analyses|Contributed to the interpretation of the findings and formulation of the report|Contributed to revision of the manuscript	Contributed to revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
1805814	17332843	KT	1	Designed the study|Peformed further statistical analyses|Contributed to the interpretation of the findings and formulation of the report|Wrote the first draft of the manuscript|Contributed to revision of the manuscript	Designed the study	Conceived and designed the experiments	Methodology	YES
1805814	17332843	KT	1	Designed the study|Peformed further statistical analyses|Contributed to the interpretation of the findings and formulation of the report|Wrote the first draft of the manuscript|Contributed to revision of the manuscript	Peformed further statistical analyses	Analyzed the data	Formal analysis	YES
1805814	17332843	KT	1	Designed the study|Peformed further statistical analyses|Contributed to the interpretation of the findings and formulation of the report|Wrote the first draft of the manuscript|Contributed to revision of the manuscript	Contributed to the interpretation of the findings and formulation of the report	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
1805814	17332843	KT	1	Designed the study|Peformed further statistical analyses|Contributed to the interpretation of the findings and formulation of the report|Wrote the first draft of the manuscript|Contributed to revision of the manuscript	Wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
1805814	17332843	KT	1	Designed the study|Peformed further statistical analyses|Contributed to the interpretation of the findings and formulation of the report|Wrote the first draft of the manuscript|Contributed to revision of the manuscript	Contributed to revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
1805814	17332843	TT	1	Designed the study|Contributed to the interpretation of the findings and formulation of the report|Contributed to revision of the manuscript	Designed the study	Conceived and designed the experiments	Methodology	YES
1805814	17332843	TT	1	Designed the study|Contributed to the interpretation of the findings and formulation of the report|Contributed to revision of the manuscript	Contributed to the interpretation of the findings and formulation of the report	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
1805814	17332843	TT	1	Designed the study|Contributed to the interpretation of the findings and formulation of the report|Contributed to revision of the manuscript	Contributed to revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
6351702	30697970	AW	2	conceived and designed the study|also contributed to analysis and interpretation of data	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6351702	30697970	AW	2	conceived and designed the study|also contributed to analysis and interpretation of data	also contributed to analysis and interpretation of data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6351702	30697970	BK	2	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6351702	30697970	S. All	2	authors commented on the paper and approved the final version	authors commented on the paper and approved the final version	-	-	NO
6351702	30697970	SH	2	collected and analysed data	collected and analysed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6351702	30697970	VD	2	collected and analysed data	collected and analysed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6351702	30697970	ZT	2	collected and analysed data	collected and analysed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4411050	25915508	DH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411050	25915508	DH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411050	25915508	DH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411050	25915508	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411050	25915508	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411050	25915508	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411050	25915508	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411050	25915508	SG	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411050	25915508	SG	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1805815	17332844	IK	PLoS5	Analyzed the data|Wrote the paper|Collected the data and revised the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1805815	17332844	IK	PLoS5	Analyzed the data|Wrote the paper|Collected the data and revised the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1805815	17332844	IK	PLoS5	Analyzed the data|Wrote the paper|Collected the data and revised the paper	Collected the data and revised the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
1805815	17332844	MF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1805815	17332844	MF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1805815	17332844	MF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5660728	29114257	BZ	2	designed the study|performed experiments|analyzed and interpreted the data|wrote the manuscript|revised the manuscript critically	designed the study	Conceived and designed the experiments	Methodology	YES
5660728	29114257	BZ	2	designed the study|performed experiments|analyzed and interpreted the data|wrote the manuscript|revised the manuscript critically	performed experiments	Performed the experiments	Investigation	YES
5660728	29114257	BZ	2	designed the study|performed experiments|analyzed and interpreted the data|wrote the manuscript|revised the manuscript critically	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5660728	29114257	BZ	2	designed the study|performed experiments|analyzed and interpreted the data|wrote the manuscript|revised the manuscript critically	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5660728	29114257	BZ	2	designed the study|performed experiments|analyzed and interpreted the data|wrote the manuscript|revised the manuscript critically	revised the manuscript critically	Wrote the paper	Writing - Review & Editing	YES
5660728	29114257	CZ	2	designed the study|performed experiments|analyzed and interpreted the data|wrote the manuscript|revised the manuscript critically	designed the study	Conceived and designed the experiments	Methodology	YES
5660728	29114257	CZ	2	designed the study|performed experiments|analyzed and interpreted the data|wrote the manuscript|revised the manuscript critically	performed experiments	Performed the experiments	Investigation	YES
5660728	29114257	CZ	2	designed the study|performed experiments|analyzed and interpreted the data|wrote the manuscript|revised the manuscript critically	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5660728	29114257	CZ	2	designed the study|performed experiments|analyzed and interpreted the data|wrote the manuscript|revised the manuscript critically	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5660728	29114257	CZ	2	designed the study|performed experiments|analyzed and interpreted the data|wrote the manuscript|revised the manuscript critically	revised the manuscript critically	Wrote the paper	Writing - Review & Editing	YES
5660728	29114257	HL	2	designed the study|performed experiments|analyzed and interpreted the data|wrote the manuscript|revised the manuscript critically	designed the study	Conceived and designed the experiments	Methodology	YES
5660728	29114257	HL	2	designed the study|performed experiments|analyzed and interpreted the data|wrote the manuscript|revised the manuscript critically	performed experiments	Performed the experiments	Investigation	YES
5660728	29114257	HL	2	designed the study|performed experiments|analyzed and interpreted the data|wrote the manuscript|revised the manuscript critically	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5660728	29114257	HL	2	designed the study|performed experiments|analyzed and interpreted the data|wrote the manuscript|revised the manuscript critically	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5660728	29114257	HL	2	designed the study|performed experiments|analyzed and interpreted the data|wrote the manuscript|revised the manuscript critically	revised the manuscript critically	Wrote the paper	Writing - Review & Editing	YES
5660728	29114257	JG	2	designed the study|analyzed and interpreted the data|revised the manuscript critically	designed the study	Conceived and designed the experiments	Methodology	YES
5660728	29114257	JG	2	designed the study|analyzed and interpreted the data|revised the manuscript critically	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5660728	29114257	JG	2	designed the study|analyzed and interpreted the data|revised the manuscript critically	revised the manuscript critically	Wrote the paper	Writing - Review & Editing	YES
5660728	29114257	JW	2	analyzed and interpreted the data	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5660728	29114257	SL	2	revised the manuscript critically	revised the manuscript critically	Wrote the paper	Writing - Review & Editing	YES
5660728	29114257	WL	2	designed the study|performed experiments|analyzed and interpreted the data|wrote the manuscript|revised the manuscript critically	designed the study	Conceived and designed the experiments	Methodology	YES
5660728	29114257	WL	2	designed the study|performed experiments|analyzed and interpreted the data|wrote the manuscript|revised the manuscript critically	performed experiments	Performed the experiments	Investigation	YES
5660728	29114257	WL	2	designed the study|performed experiments|analyzed and interpreted the data|wrote the manuscript|revised the manuscript critically	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5660728	29114257	WL	2	designed the study|performed experiments|analyzed and interpreted the data|wrote the manuscript|revised the manuscript critically	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5660728	29114257	WL	2	designed the study|performed experiments|analyzed and interpreted the data|wrote the manuscript|revised the manuscript critically	revised the manuscript critically	Wrote the paper	Writing - Review & Editing	YES
5660728	29114257	WW	2	analyzed and interpreted the data	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
6351749	30697950	A.G.	PLoS52	conducted the observational research and led data collection|designed the study|wrote the paper	conducted the observational research and led data collection	Performed the experiments	Investigation	YES
6351749	30697950	A.G.	PLoS52	conducted the observational research and led data collection|designed the study|wrote the paper	designed the study	Conceived and designed the experiments	Methodology	YES
6351749	30697950	A.G.	PLoS52	conducted the observational research and led data collection|designed the study|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6351749	30697950	B.G.	PLoS52	conducted the observational research and led data collection|designed the study|wrote the paper	conducted the observational research and led data collection	Performed the experiments	Investigation	YES
6351749	30697950	B.G.	PLoS52	conducted the observational research and led data collection|designed the study|wrote the paper	designed the study	Conceived and designed the experiments	Methodology	YES
6351749	30697950	B.G.	PLoS52	conducted the observational research and led data collection|designed the study|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6351749	30697950	C.B.	PLoS52	conducted the observational research and led data collection	conducted the observational research and led data collection	Performed the experiments	Investigation	YES
6351749	30697950	C.C.M.	PLoS52	conducted data quality assessments|designed the study|wrote the paper	conducted data quality assessments	-	Data curation|Validation	YES
6351749	30697950	C.C.M.	PLoS52	conducted data quality assessments|designed the study|wrote the paper	designed the study	Conceived and designed the experiments	Methodology	YES
6351749	30697950	C.C.M.	PLoS52	conducted data quality assessments|designed the study|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6351749	30697950	J.L.C.	PLoS52	conducted data quality assessments|designed the study|analysed the data|wrote the paper	conducted data quality assessments	-	Data curation|Validation	YES
6351749	30697950	J.L.C.	PLoS52	conducted data quality assessments|designed the study|analysed the data|wrote the paper	designed the study	Conceived and designed the experiments	Methodology	YES
6351749	30697950	J.L.C.	PLoS52	conducted data quality assessments|designed the study|analysed the data|wrote the paper	analysed the data	Analyzed the data	Formal analysis	YES
6351749	30697950	J.L.C.	PLoS52	conducted data quality assessments|designed the study|analysed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6351749	30697950	J.O.G.	PLoS52	conducted the observational research and led data collection|conducted data quality assessments	conducted the observational research and led data collection	Performed the experiments	Investigation	YES
6351749	30697950	J.O.G.	PLoS52	conducted the observational research and led data collection|conducted data quality assessments	conducted data quality assessments	-	Data curation|Validation	YES
6351749	30697950	K.J.	PLoS52	conducted data quality assessments|analysed the data	conducted data quality assessments	-	Data curation|Validation	YES
6351749	30697950	K.J.	PLoS52	conducted data quality assessments|analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
6351749	30697950	M.L.R.I.	PLoS52	conducted the observational research and led data collection	conducted the observational research and led data collection	Performed the experiments	Investigation	YES
6351749	30697950	M.M.E.	PLoS52	conducted the observational research and led data collection|designed the study|wrote the paper	conducted the observational research and led data collection	Performed the experiments	Investigation	YES
6351749	30697950	M.M.E.	PLoS52	conducted the observational research and led data collection|designed the study|wrote the paper	designed the study	Conceived and designed the experiments	Methodology	YES
6351749	30697950	M.M.E.	PLoS52	conducted the observational research and led data collection|designed the study|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6351749	30697950	P.R.A.	PLoS52	conducted the observational research and led data collection	conducted the observational research and led data collection	Performed the experiments	Investigation	YES
6351749	30697950	R.A.S.	PLoS52	conducted the observational research and led data collection	conducted the observational research and led data collection	Performed the experiments	Investigation	YES
6351749	30697950	S.R.	PLoS52	conducted the observational research and led data collection|conducted data quality assessments	conducted the observational research and led data collection	Performed the experiments	Investigation	YES
6351749	30697950	S.R.	PLoS52	conducted the observational research and led data collection|conducted data quality assessments	conducted data quality assessments	-	Data curation|Validation	YES
6351749	30697950	U.T.	PLoS52	conducted the observational research and led data collection	conducted the observational research and led data collection	Performed the experiments	Investigation	YES
6351749	30697950	V.V.	PLoS52	conducted the observational research and led data collection|designed the study	conducted the observational research and led data collection	Performed the experiments	Investigation	YES
6351749	30697950	V.V.	PLoS52	conducted the observational research and led data collection|designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5490230	28659132	TJG	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5490230	28659132	YYC	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5379042	28373382	D.B.	2	contributed equally to this work and gave final approval for publication	contributed equally to this work and gave final approval for publication	-	-	NO
5379042	28373382	P.A.G.	2	contributed equally to this work and gave final approval for publication	contributed equally to this work and gave final approval for publication	-	-	NO
4563089	26380300	Anna Mertas	2	contributed equally to this work	contributed equally to this work	-	-	NO
4563089	26380300	Tadeusz Morawiec	2	contributed equally to this work	contributed equally to this work	-	-	NO
4411051	25915423	CJM	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4411051	25915423	DDK	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4411051	25915423	HJC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411051	25915423	HJC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411051	25915423	HJC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411051	25915423	HJK	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4411051	25915423	JBW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411051	25915423	JP	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411051	25915423	JP	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411051	25915423	JYL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411051	25915423	WSK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411051	25915423	WSK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411051	25915423	WSK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1805816	17332845	DM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1805816	17332845	DM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1805816	17332845	DM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1805816	17332845	EE	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1805816	17332845	EE	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1805816	17332845	EE	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1805816	17332845	JI	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1805816	17332845	JI	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1805816	17332845	JI	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5909676	29732124	H.C.M.	PLoS52	analysed the experimental data, discussed the results, and wrote the manuscript	analysed the experimental data, discussed the results, and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5909676	29732124	I.K.	PLoS52	performed computational simulations	performed computational simulations	Performed the experiments	Formal analysis|Investigation	YES
5909676	29732124	I.Y.	PLoS52	participated in the sample preparation	participated in the sample preparation	Performed the experiments	Investigation	YES
5909676	29732124	S.C.	PLoS52	participated in the sample preparation	participated in the sample preparation	Performed the experiments	Investigation	YES
5909676	29732124	S.S.	PLoS52	designed the research|performed the experiments|analysed the experimental data, discussed the results, and wrote the manuscript|contributed equally to this study	designed the research	Conceived and designed the experiments	Methodology	YES
5909676	29732124	S.S.	PLoS52	designed the research|performed the experiments|analysed the experimental data, discussed the results, and wrote the manuscript|contributed equally to this study	performed the experiments	Performed the experiments	Investigation	YES
5909676	29732124	S.S.	PLoS52	designed the research|performed the experiments|analysed the experimental data, discussed the results, and wrote the manuscript|contributed equally to this study	analysed the experimental data, discussed the results, and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5909676	29732124	S.S.	PLoS52	designed the research|performed the experiments|analysed the experimental data, discussed the results, and wrote the manuscript|contributed equally to this study	contributed equally to this study	-	-	NO
5909676	29732124	U.J.	PLoS52	designed the research|analysed the experimental data, discussed the results, and wrote the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
5909676	29732124	U.J.	PLoS52	designed the research|analysed the experimental data, discussed the results, and wrote the manuscript	analysed the experimental data, discussed the results, and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5909676	29732124	Y.P.	PLoS52	performed computational simulations|analysed the experimental data, discussed the results, and wrote the manuscript|contributed equally to this study	performed computational simulations	Performed the experiments	Formal analysis|Investigation	YES
5909676	29732124	Y.P.	PLoS52	performed computational simulations|analysed the experimental data, discussed the results, and wrote the manuscript|contributed equally to this study	analysed the experimental data, discussed the results, and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5909676	29732124	Y.P.	PLoS52	performed computational simulations|analysed the experimental data, discussed the results, and wrote the manuscript|contributed equally to this study	contributed equally to this study	-	-	NO
5490237	28659185	MIZ	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5490237	28659185	NVR	PLoS52	wrote the paper|conceived of the research and designed the study	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5490237	28659185	NVR	PLoS52	wrote the paper|conceived of the research and designed the study	conceived of the research and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5490237	28659185	OAD	PLoS52	conceived of the research and designed the study	conceived of the research and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5490237	28659185	OAP	PLoS52	made phenotype tests	made phenotype tests	Performed the experiments	Investigation	YES
5490237	28659185	OIL	PLoS52	wrote the paper|conceived of the research and designed the study	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5490237	28659185	OIL	PLoS52	wrote the paper|conceived of the research and designed the study	conceived of the research and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5490237	28659185	YYP	PLoS52	made phenotype tests	made phenotype tests	Performed the experiments	Investigation	YES
5660730	29114253	AY	2	performed research	performed research	Performed the experiments	Investigation	YES
5660730	29114253	BD	2	designed the research|analyzed data and wrote the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
5660730	29114253	BD	2	designed the research|analyzed data and wrote the manuscript	analyzed data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5660730	29114253	GH	2	designed the research|analyzed data and wrote the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
5660730	29114253	GH	2	designed the research|analyzed data and wrote the manuscript	analyzed data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5660730	29114253	LZ	2	performed research	performed research	Performed the experiments	Investigation	YES
5660730	29114253	RC	2	performed research	performed research	Performed the experiments	Investigation	YES
5660730	29114253	SS	2	performed research	performed research	Performed the experiments	Investigation	YES
5660730	29114253	XS	2	performed research	performed research	Performed the experiments	Investigation	YES
5660730	29114253	YM	2	designed the research|performed research|analyzed data and wrote the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
5660730	29114253	YM	2	designed the research|performed research|analyzed data and wrote the manuscript	performed research	Performed the experiments	Investigation	YES
5660730	29114253	YM	2	designed the research|performed research|analyzed data and wrote the manuscript	analyzed data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5660730	29114253	YW	2	performed research	performed research	Performed the experiments	Investigation	YES
5660730	29114253	YZe	2	performed research	performed research	Performed the experiments	Investigation	YES
5660730	29114253	YZh	2	performed research	performed research	Performed the experiments	Investigation	YES
6364490	30724470	All other authors	2	revised the first draft and provided critical review to subsequent drafts	revised the first draft and provided critical review to subsequent drafts	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6364490	30724470	FZ	2	designed the study|developed the study protocol including development the data collection tool and study analytic plan|were responsible for critical review of the study protocol, carrying out of the study, conducting the data collection, data quality control and data management	designed the study	Conceived and designed the experiments	Methodology	YES
6364490	30724470	FZ	2	designed the study|developed the study protocol including development the data collection tool and study analytic plan|were responsible for critical review of the study protocol, carrying out of the study, conducting the data collection, data quality control and data management	developed the study protocol including development the data collection tool and study analytic plan	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
6364490	30724470	FZ	2	designed the study|developed the study protocol including development the data collection tool and study analytic plan|were responsible for critical review of the study protocol, carrying out of the study, conducting the data collection, data quality control and data management	were responsible for critical review of the study protocol, carrying out of the study, conducting the data collection, data quality control and data management	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Data curation|Investigation|Methodology|Validation	YES
6364490	30724470	GM	2	developed the study protocol including development the data collection tool and study analytic plan|were responsible for critical review of the study protocol, carrying out of the study, conducting the data collection, data quality control and data management	developed the study protocol including development the data collection tool and study analytic plan	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
6364490	30724470	GM	2	developed the study protocol including development the data collection tool and study analytic plan|were responsible for critical review of the study protocol, carrying out of the study, conducting the data collection, data quality control and data management	were responsible for critical review of the study protocol, carrying out of the study, conducting the data collection, data quality control and data management	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Data curation|Investigation|Methodology|Validation	YES
6364490	30724470	JB	2	performed the data cleaning and statistical analysis|wrote the first draft of the manuscript	performed the data cleaning and statistical analysis	Analyzed the data	Data curation|Formal analysis	YES
6364490	30724470	JB	2	performed the data cleaning and statistical analysis|wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
6364490	30724470	JH	2	designed the study|developed the study protocol including development the data collection tool and study analytic plan|were responsible for critical review of the study protocol, carrying out of the study, conducting the data collection, data quality control and data management|wrote the first draft of the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
6364490	30724470	JH	2	designed the study|developed the study protocol including development the data collection tool and study analytic plan|were responsible for critical review of the study protocol, carrying out of the study, conducting the data collection, data quality control and data management|wrote the first draft of the manuscript	developed the study protocol including development the data collection tool and study analytic plan	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
6364490	30724470	JH	2	designed the study|developed the study protocol including development the data collection tool and study analytic plan|were responsible for critical review of the study protocol, carrying out of the study, conducting the data collection, data quality control and data management|wrote the first draft of the manuscript	were responsible for critical review of the study protocol, carrying out of the study, conducting the data collection, data quality control and data management	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Data curation|Investigation|Methodology|Validation	YES
6364490	30724470	JH	2	designed the study|developed the study protocol including development the data collection tool and study analytic plan|were responsible for critical review of the study protocol, carrying out of the study, conducting the data collection, data quality control and data management|wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
6364490	30724470	LW	2	designed the study|developed the study protocol including development the data collection tool and study analytic plan|were responsible for critical review of the study protocol, carrying out of the study, conducting the data collection, data quality control and data management	designed the study	Conceived and designed the experiments	Methodology	YES
6364490	30724470	LW	2	designed the study|developed the study protocol including development the data collection tool and study analytic plan|were responsible for critical review of the study protocol, carrying out of the study, conducting the data collection, data quality control and data management	developed the study protocol including development the data collection tool and study analytic plan	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
6364490	30724470	LW	2	designed the study|developed the study protocol including development the data collection tool and study analytic plan|were responsible for critical review of the study protocol, carrying out of the study, conducting the data collection, data quality control and data management	were responsible for critical review of the study protocol, carrying out of the study, conducting the data collection, data quality control and data management	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Data curation|Investigation|Methodology|Validation	YES
6364490	30724470	TV	2	wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
6364490	30724470	YH	2	performed the data cleaning and statistical analysis	performed the data cleaning and statistical analysis	Analyzed the data	Data curation|Formal analysis	YES
6364490	30724470	ZC	2	developed the study protocol including development the data collection tool and study analytic plan|were responsible for critical review of the study protocol, carrying out of the study, conducting the data collection, data quality control and data management	developed the study protocol including development the data collection tool and study analytic plan	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
6364490	30724470	ZC	2	developed the study protocol including development the data collection tool and study analytic plan|were responsible for critical review of the study protocol, carrying out of the study, conducting the data collection, data quality control and data management	were responsible for critical review of the study protocol, carrying out of the study, conducting the data collection, data quality control and data management	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Data curation|Investigation|Methodology|Validation	YES
1805817	17332846	GM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1805817	17332846	GM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1805817	17332846	GM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1805817	17332846	GM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1805817	17332846	GM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1805817	17332846	JC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1805817	17332846	JC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1805817	17332846	JC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1805817	17332846	JC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1805817	17332846	JC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1805817	17332846	JW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1805817	17332846	JW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1805817	17332846	JW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1805817	17332846	JW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1805817	17332846	JW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1805817	17332846	KW	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1805817	17332846	KW	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1805817	17332846	KW	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1805817	17332846	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1805817	17332846	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1805817	17332846	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1805817	17332846	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1805817	17332846	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1805817	17332846	SP	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5394257	28416729	L.T.E.-T.	2	conceived the research and jointly interpreted results, wrote the paper and approved of its content prior to publication	conceived the research and jointly interpreted results, wrote the paper and approved of its content prior to publication	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
5394257	28416729	S.M.T.	2	conceived the research and jointly interpreted results, wrote the paper and approved of its content prior to publication|conducted the magma ocean modelling	conceived the research and jointly interpreted results, wrote the paper and approved of its content prior to publication	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
5394257	28416729	S.M.T.	2	conceived the research and jointly interpreted results, wrote the paper and approved of its content prior to publication|conducted the magma ocean modelling	conducted the magma ocean modelling	Performed the experiments	Investigation|Methodology	YES
5660857	29114258	FX	2	designed and supervised the study	designed and supervised the study	Conceived and designed the experiments	Methodology|Supervision	YES
5660857	29114258	HaC	2	conducted most of the experiments|analyzed the data and wrote the paper	conducted most of the experiments	Performed the experiments	Investigation	YES
5660857	29114258	HaC	2	conducted most of the experiments|analyzed the data and wrote the paper	analyzed the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5660857	29114258	HoC	2	performed the transcriptional analysis|participated in the proton flux assessment	performed the transcriptional analysis	Performed the experiments	Investigation	YES
5660857	29114258	HoC	2	performed the transcriptional analysis|participated in the proton flux assessment	participated in the proton flux assessment	-	-	NO
5660857	29114258	QZ	2	performed the transcriptional analysis|participated in the proton flux assessment	performed the transcriptional analysis	Performed the experiments	Investigation	YES
5660857	29114258	QZ	2	performed the transcriptional analysis|participated in the proton flux assessment	participated in the proton flux assessment	-	-	NO
4411052	25915947	CL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411052	25915947	CW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411052	25915947	DW	PLoS5	Contributed to supervision	Contributed to supervision	-	Supervision	YES
4411052	25915947	HD	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411052	25915947	HD	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411052	25915947	HS	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411052	25915947	HS	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411052	25915947	HW	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411052	25915947	HW	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411052	25915947	HZ	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4411052	25915947	KN	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Contributed to supervision	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411052	25915947	KN	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Contributed to supervision	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411052	25915947	KN	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Contributed to supervision	Contributed to supervision	-	Supervision	YES
4411052	25915947	KS	PLoS5	Contributed to supervision	Contributed to supervision	-	Supervision	YES
4411052	25915947	LL	PLoS5	Contributed to supervision	Contributed to supervision	-	Supervision	YES
4411052	25915947	MZ	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4411052	25915947	QJ	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4411052	25915947	QZ	PLoS5	Contributed to supervision	Contributed to supervision	-	Supervision	YES
4411052	25915947	SS	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4411052	25915947	XG	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411052	25915947	XG	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411052	25915947	XG	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411052	25915947	XL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411052	25915947	XW	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4411052	25915947	YX	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
549213	15676066	DPhil	2	student who worked on the coding aspects of the new methodology	student who worked on the coding aspects of the new methodology	Performed the experiments	Methodology	YES
549213	15676066	JFP	2	contributed to the bioinformatics discussions and planning stage of this project	contributed to the bioinformatics discussions and planning stage of this project	Conceived and designed the experiments	Formal analysis|Methodology	YES
549213	15676066	NJS	2	initiated the project, performed the genome sequence analyses, compared the two strains, interpreted the results, and prepared the biological aspects of the manuscript	initiated the project, performed the genome sequence analyses, compared the two strains, interpreted the results, and prepared the biological aspects of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
549213	15676066	SAJ	2	directed and primarily developed the analysis strategy and the implementation of the new computational basis of the methodology, and prepared the computational aspects of the manuscript	directed and primarily developed the analysis strategy and the implementation of the new computational basis of the methodology, and prepared the computational aspects of the manuscript	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Methodology|Supervision|Writing - Original Draft	YES
3373122	22701485	E. Ferreiro	2	contributed equally to the paper	contributed equally to the paper	-	-	NO
3373122	22701485	I. Baldeiras	2	contributed equally to the paper	contributed equally to the paper	-	-	NO
3373122	22701485	I. L. Ferreira	2	contributed equally to the paper	contributed equally to the paper	-	-	NO
5660868	29114255	All authors	2	listed have made a substantial, direct and intellectual contribution to the work, and approved it for publication	listed have made a substantial, direct and intellectual contribution to the work, and approved it for publication	-	-	NO
1805818	17332847	KS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1805818	17332847	KS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1805818	17332847	KS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1805818	17332847	KS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1805818	17332847	KS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1805818	17332847	LB	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1805818	17332847	MD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1805818	17332847	MD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1805818	17332847	MD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1805818	17332847	MD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1805818	17332847	MU	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1805818	17332847	MU	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1805818	17332847	MU	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1805818	17332847	QN	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1805818	17332847	SG	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1805818	17332847	SW	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1805818	17332847	SW	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1805818	17332847	TR	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1805818	17332847	TR	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5415645	28461428	A.C.S.	2	have carried out data analysis, built the model, designed the study and drafted the manuscript	have carried out data analysis, built the model, designed the study and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5415645	28461428	J.B.N.	2	have carried out data analysis, built the model, designed the study and drafted the manuscript	have carried out data analysis, built the model, designed the study and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5415645	28461428	J.M.A.	2	conceived of the study, coordinated the analysis and helped draft the manuscript	conceived of the study, coordinated the analysis and helped draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Project administration|Writing - Original Draft	YES
3375158	22719766	A.R.	2	designed research	designed research	Conceived and designed the experiments	Methodology	YES
3375158	22719766	H.-H.G.	2	designed research	designed research	Conceived and designed the experiments	Methodology	YES
3375158	22719766	N.V.B.	2	designed research|performed all experiments	designed research	Conceived and designed the experiments	Methodology	YES
3375158	22719766	N.V.B.	2	designed research|performed all experiments	performed all experiments	Performed the experiments	Investigation	YES
3375158	22719766	P.E.	2	performed initial experiments on cell cycle synchronization and confocal imaging of mitotic cells	performed initial experiments on cell cycle synchronization and confocal imaging of mitotic cells	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
4411053	25915927	LL	PLoS5	Conceived and designed the experiments|Revised the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411053	25915927	LL	PLoS5	Conceived and designed the experiments|Revised the paper	Revised the paper	Wrote the paper	Writing - Review & Editing	YES
4411053	25915927	SMW	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411053	25915927	SMW	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411053	25915927	SMW	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411053	25915927	SMW	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411053	25915927	YLL	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411053	25915927	YLL	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5492280	28662642	HZ	PLoS52	prepared plant materials and carried out qpcr analysis|wrote the manuscript and all authors read and approved the final version	prepared plant materials and carried out qpcr analysis	Performed the experiments	Investigation	YES
5492280	28662642	HZ	PLoS52	prepared plant materials and carried out qpcr analysis|wrote the manuscript and all authors read and approved the final version	wrote the manuscript and all authors read and approved the final version	Wrote the paper	Writing - Original Draft	YES
5492280	28662642	JFZ	PLoS52	prepared plant materials and carried out qpcr analysis|wrote the manuscript and all authors read and approved the final version	prepared plant materials and carried out qpcr analysis	Performed the experiments	Investigation	YES
5492280	28662642	JFZ	PLoS52	prepared plant materials and carried out qpcr analysis|wrote the manuscript and all authors read and approved the final version	wrote the manuscript and all authors read and approved the final version	Wrote the paper	Writing - Original Draft	YES
5492280	28662642	JJ	PLoS52	conceived and designed the experiments|performed the rna sequencing and bioinformatics data processing|wrote the manuscript and all authors read and approved the final version	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5492280	28662642	JJ	PLoS52	conceived and designed the experiments|performed the rna sequencing and bioinformatics data processing|wrote the manuscript and all authors read and approved the final version	performed the rna sequencing and bioinformatics data processing	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5492280	28662642	JJ	PLoS52	conceived and designed the experiments|performed the rna sequencing and bioinformatics data processing|wrote the manuscript and all authors read and approved the final version	wrote the manuscript and all authors read and approved the final version	Wrote the paper	Writing - Original Draft	YES
5492280	28662642	PJC	PLoS52	conceived and designed the experiments|wrote the manuscript and all authors read and approved the final version	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5492280	28662642	PJC	PLoS52	conceived and designed the experiments|wrote the manuscript and all authors read and approved the final version	wrote the manuscript and all authors read and approved the final version	Wrote the paper	Writing - Original Draft	YES
5492280	28662642	PL	PLoS52	performed the rna sequencing and bioinformatics data processing	performed the rna sequencing and bioinformatics data processing	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5492280	28662642	PP	PLoS52	did the gc-ms and lc-ms experiments	did the gc-ms and lc-ms experiments	Performed the experiments	Investigation	YES
5492280	28662642	XC	PLoS52	did the gc-ms and lc-ms experiments	did the gc-ms and lc-ms experiments	Performed the experiments	Investigation	YES
5492280	28662642	YLX	PLoS52	performed the rna sequencing and bioinformatics data processing	performed the rna sequencing and bioinformatics data processing	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5492280	28662642	ZFL	PLoS52	performed the rna sequencing and bioinformatics data processing	performed the rna sequencing and bioinformatics data processing	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
6367572	30734510	AA	2	conceived the idea and designed study|were involved in study design, contributed to the intellectual content and contributed to writing subsequent drafts of the paper|contributed to the interpretation of data and revising the work critically	conceived the idea and designed study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6367572	30734510	AA	2	conceived the idea and designed study|were involved in study design, contributed to the intellectual content and contributed to writing subsequent drafts of the paper|contributed to the interpretation of data and revising the work critically	were involved in study design, contributed to the intellectual content and contributed to writing subsequent drafts of the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
6367572	30734510	AA	2	conceived the idea and designed study|were involved in study design, contributed to the intellectual content and contributed to writing subsequent drafts of the paper|contributed to the interpretation of data and revising the work critically	contributed to the interpretation of data and revising the work critically	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6367572	30734510	AKC	2	were involved in study design, contributed to the intellectual content and contributed to writing subsequent drafts of the paper|contributed to the interpretation of data and revising the work critically	were involved in study design, contributed to the intellectual content and contributed to writing subsequent drafts of the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
6367572	30734510	AKC	2	were involved in study design, contributed to the intellectual content and contributed to writing subsequent drafts of the paper|contributed to the interpretation of data and revising the work critically	contributed to the interpretation of data and revising the work critically	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6367572	30734510	AM	2	contributed to the acquisition of data|were responsible for data management, statistical analysis and provided feedback on drafts of the paper	contributed to the acquisition of data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
6367572	30734510	AM	2	contributed to the acquisition of data|were responsible for data management, statistical analysis and provided feedback on drafts of the paper	were responsible for data management, statistical analysis and provided feedback on drafts of the paper	Analyzed the data|Wrote the paper	Data curation|Formal analysis|Writing - Original Draft	YES
6367572	30734510	All authors	2	reviewed and approved the final manuscript	reviewed and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6367572	30734510	ES	2	contributed to the intellectual content and commented on drafts the paper|were responsible for data management, statistical analysis and provided feedback on drafts of the paper	contributed to the intellectual content and commented on drafts the paper	Wrote the paper	Writing - Original Draft	YES
6367572	30734510	ES	2	contributed to the intellectual content and commented on drafts the paper|were responsible for data management, statistical analysis and provided feedback on drafts of the paper	were responsible for data management, statistical analysis and provided feedback on drafts of the paper	Analyzed the data|Wrote the paper	Data curation|Formal analysis|Writing - Original Draft	YES
6367572	30734510	GK	2	contributed to the intellectual content and commented on drafts the paper|contributed to the acquisition of data	contributed to the intellectual content and commented on drafts the paper	Wrote the paper	Writing - Original Draft	YES
6367572	30734510	GK	2	contributed to the intellectual content and commented on drafts the paper|contributed to the acquisition of data	contributed to the acquisition of data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
6367572	30734510	JJvO	2	were involved in study design, contributed to the intellectual content and contributed to writing subsequent drafts of the paper|contributed to the interpretation of data and revising the work critically	were involved in study design, contributed to the intellectual content and contributed to writing subsequent drafts of the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
6367572	30734510	JJvO	2	were involved in study design, contributed to the intellectual content and contributed to writing subsequent drafts of the paper|contributed to the interpretation of data and revising the work critically	contributed to the interpretation of data and revising the work critically	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6367572	30734510	JT	2	contributed to the intellectual content and commented on drafts the paper|contributed to the interpretation of data and revising the work critically	contributed to the intellectual content and commented on drafts the paper	Wrote the paper	Writing - Original Draft	YES
6367572	30734510	JT	2	contributed to the intellectual content and commented on drafts the paper|contributed to the interpretation of data and revising the work critically	contributed to the interpretation of data and revising the work critically	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6367572	30734510	MA	2	was responsible for overall data management, analysis and wrote the first draft of the paper|were responsible for data management, statistical analysis and provided feedback on drafts of the paper	was responsible for overall data management, analysis and wrote the first draft of the paper	Analyzed the data|Wrote the paper	Data curation|Formal analysis|Writing - Original Draft	YES
6367572	30734510	MA	2	was responsible for overall data management, analysis and wrote the first draft of the paper|were responsible for data management, statistical analysis and provided feedback on drafts of the paper	were responsible for data management, statistical analysis and provided feedback on drafts of the paper	Analyzed the data|Wrote the paper	Data curation|Formal analysis|Writing - Original Draft	YES
6367572	30734510	MJ	2	contributed to the intellectual content and commented on drafts the paper|contributed to the interpretation of data and revising the work critically	contributed to the intellectual content and commented on drafts the paper	Wrote the paper	Writing - Original Draft	YES
6367572	30734510	MJ	2	contributed to the intellectual content and commented on drafts the paper|contributed to the interpretation of data and revising the work critically	contributed to the interpretation of data and revising the work critically	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6367572	30734510	MvL	2	contributed to the intellectual content and commented on drafts the paper|contributed to the interpretation of data and revising the work critically	contributed to the intellectual content and commented on drafts the paper	Wrote the paper	Writing - Original Draft	YES
6367572	30734510	MvL	2	contributed to the intellectual content and commented on drafts the paper|contributed to the interpretation of data and revising the work critically	contributed to the interpretation of data and revising the work critically	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6367572	30734510	VB	2	contributed to the acquisition of data|were responsible for data management, statistical analysis and provided feedback on drafts of the paper	contributed to the acquisition of data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
6367572	30734510	VB	2	contributed to the acquisition of data|were responsible for data management, statistical analysis and provided feedback on drafts of the paper	were responsible for data management, statistical analysis and provided feedback on drafts of the paper	Analyzed the data|Wrote the paper	Data curation|Formal analysis|Writing - Original Draft	YES
5660973	29118781	All authors	2	contributed to the design of the study	contributed to the design of the study	Conceived and designed the experiments	Methodology	YES
5660973	29118781	RW	2	with the	with the	-	-	NO
5660973	29118781	all other authors	2	helped rw with the	helped rw with the	-	-	NO
4564579	26413516	Joerg Klaws	PLoS52	developed the methodology	developed the methodology	Performed the experiments	Methodology	YES
4564579	26413516	Magdalena Muller-Gerbl	PLoS52	designed the study and collected the data	designed the study and collected the data	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4564579	26413516	Mireille Toranelli	PLoS52	contributed the histology work	contributed the histology work	Performed the experiments	Investigation	YES
4564579	26413516	Nicole Helene Hauser	PLoS52	designed the study and collected the data|wrote the paper|contributed equally to this work	designed the study and collected the data	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4564579	26413516	Nicole Helene Hauser	PLoS52	designed the study and collected the data|wrote the paper|contributed equally to this work	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4564579	26413516	Nicole Helene Hauser	PLoS52	designed the study and collected the data|wrote the paper|contributed equally to this work	contributed equally to this work	-	-	NO
4564579	26413516	Sebastian Hoechel	PLoS52	developed the methodology|wrote the paper|contributed equally to this work	developed the methodology	Performed the experiments	Methodology	YES
4564579	26413516	Sebastian Hoechel	PLoS52	developed the methodology|wrote the paper|contributed equally to this work	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4564579	26413516	Sebastian Hoechel	PLoS52	developed the methodology|wrote the paper|contributed equally to this work	contributed equally to this work	-	-	NO
1808422	17356700	AM	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1808422	17356700	DR	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1808422	17356700	DR	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1808422	17356700	EH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1808422	17356700	EH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1808422	17356700	EH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1808422	17356700	EO	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1808422	17356700	EO	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1808422	17356700	EO	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1808422	17356700	EO	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1808422	17356700	FA	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1808422	17356700	FA	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1808422	17356700	JG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1808422	17356700	JG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1808422	17356700	JG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1808422	17356700	JG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1808422	17356700	LB	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1808422	17356700	LB	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1808422	17356700	SD	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1808422	17356700	SD	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1808422	17356700	VC	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1808422	17356700	VC	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5415650	28461437	A.H.	2	assisted with the qualitative data analysis and assisted with editing and revising the paper	assisted with the qualitative data analysis and assisted with editing and revising the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5415650	28461437	A.S.	2	undertook the quantitative data collection and analysis and assisted with revising the paper	undertook the quantitative data collection and analysis and assisted with revising the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
5415650	28461437	T.R.	2	carried out the qualitative fieldwork, designed the study and drafted the paper	carried out the qualitative fieldwork, designed the study and drafted the paper	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5492678	28662696	AC	PLoS52	conceived and designed the experiments|provided comments on the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5492678	28662696	AC	PLoS52	conceived and designed the experiments|provided comments on the manuscript	provided comments on the manuscript	-	-	NO
5492678	28662696	AVH	PLoS52	conducted the sequencing of the strains	conducted the sequencing of the strains	Performed the experiments	Investigation	YES
5492678	28662696	JAGR	PLoS52	conducted the experiments	conducted the experiments	Performed the experiments	Investigation	YES
5492678	28662696	JEK	PLoS52	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5492678	28662696	JK	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5492678	28662696	LBS	PLoS52	conceived and designed the experiments|conducted transcriptome and main analyses|wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5492678	28662696	LBS	PLoS52	conceived and designed the experiments|conducted transcriptome and main analyses|wrote the manuscript	conducted transcriptome and main analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5492678	28662696	LBS	PLoS52	conceived and designed the experiments|conducted transcriptome and main analyses|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5492678	28662696	MGS	PLoS52	conducted the experiments|conducted transcriptome and main analyses|wrote the manuscript	conducted the experiments	Performed the experiments	Investigation	YES
5492678	28662696	MGS	PLoS52	conducted the experiments|conducted transcriptome and main analyses|wrote the manuscript	conducted transcriptome and main analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5492678	28662696	MGS	PLoS52	conducted the experiments|conducted transcriptome and main analyses|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5492678	28662696	RB	PLoS52	conducted the experiments|conducted the sequencing of the strains	conducted the experiments	Performed the experiments	Investigation	YES
5492678	28662696	RB	PLoS52	conducted the experiments|conducted the sequencing of the strains	conducted the sequencing of the strains	Performed the experiments	Investigation	YES
5492678	28662696	RJMV	PLoS52	conducted the experiments|provided comments on the manuscript	conducted the experiments	Performed the experiments	Investigation	YES
5492678	28662696	RJMV	PLoS52	conducted the experiments|provided comments on the manuscript	provided comments on the manuscript	-	-	NO
5492678	28662696	RPJB	PLoS52	conducted the experiments|conducted transcriptome and main analyses|provided comments on the manuscript	conducted the experiments	Performed the experiments	Investigation	YES
5492678	28662696	RPJB	PLoS52	conducted the experiments|conducted transcriptome and main analyses|provided comments on the manuscript	conducted transcriptome and main analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5492678	28662696	RPJB	PLoS52	conducted the experiments|conducted transcriptome and main analyses|provided comments on the manuscript	provided comments on the manuscript	-	-	NO
4411054	25915745	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411054	25915745	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411054	25915745	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411054	25915745	AT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411054	25915745	AT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411054	25915745	AT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411054	25915745	AT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411054	25915745	BD	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411054	25915745	BD	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411054	25915745	BD	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411054	25915745	FC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411054	25915745	FC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411054	25915745	FC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411054	25915745	MCS	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411054	25915745	MCS	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411054	25915745	SvdH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411054	25915745	SvdH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411054	25915745	SvdH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411054	25915745	VS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411054	25915745	VS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411054	25915745	VS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411054	25915745	VS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1808423	17356701	AS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1808423	17356701	AS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1808423	17356701	AS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1808423	17356701	ES	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1808423	17356701	IB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1808423	17356701	IB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1808423	17356701	IB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1808423	17356701	JM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1808423	17356701	JM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1808423	17356701	JM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1808423	17356701	LH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1808423	17356701	LH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1808423	17356701	MB	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1808423	17356701	MR	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1808423	17356701	RG	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1808423	17356701	RH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1808423	17356701	RH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1808423	17356701	RH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1808423	17356701	SH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1808423	17356701	SH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1808423	17356701	SH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5660990	29118773	AA	2	conceived the idea, revised the literature and drafted the manuscript	conceived the idea, revised the literature and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
5660990	29118773	AZ	2	supervised the work and provided critical suggestions on the article	supervised the work and provided critical suggestions on the article	-	Supervision	YES
5660990	29118773	CM	2	supervised the work and provided critical suggestions on the article	supervised the work and provided critical suggestions on the article	-	Supervision	YES
5660990	29118773	FL-R	2	supervised the work and provided critical suggestions on the article	supervised the work and provided critical suggestions on the article	-	Supervision	YES
5660990	29118773	JH	2	supervised the work and provided critical suggestions on the article	supervised the work and provided critical suggestions on the article	-	Supervision	YES
5660990	29118773	MG	2	supervised the work and provided critical suggestions on the article	supervised the work and provided critical suggestions on the article	-	Supervision	YES
6371013	30746898	AC	2	contributed to the design of the study and oversaw the data collection	contributed to the design of the study and oversaw the data collection	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources|Supervision	YES
6371013	30746898	ACT	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
6371013	30746898	AK	2	contributed to the design of the study and oversaw the data collection	contributed to the design of the study and oversaw the data collection	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources|Supervision	YES
6371013	30746898	All authors	2	contributed to the execution of the work presented in the manuscript, and all critically reviewed and approved the final version	contributed to the execution of the work presented in the manuscript, and all critically reviewed and approved the final version	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
6371013	30746898	CO	2	designed the study|led the study	designed the study	Conceived and designed the experiments	Methodology	YES
6371013	30746898	CO	2	designed the study|led the study	led the study	-	-	NO
6371013	30746898	DRB	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
6371013	30746898	GA	2	led the study	led the study	-	-	NO
6371013	30746898	JEH	2	designed the study|led the study|wrote the first draft of the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
6371013	30746898	JEH	2	designed the study|led the study|wrote the first draft of the manuscript	led the study	-	-	NO
6371013	30746898	JEH	2	designed the study|led the study|wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
6371013	30746898	KB	2	contributed to the design of the study and oversaw the data collection	contributed to the design of the study and oversaw the data collection	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources|Supervision	YES
6371013	30746898	LTM	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
6371013	30746898	MBB	2	designed the study|led the study	designed the study	Conceived and designed the experiments	Methodology	YES
6371013	30746898	MBB	2	designed the study|led the study	led the study	-	-	NO
6371013	30746898	MJS	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
6371013	30746898	NK	2	contributed to the design of the study and oversaw the data collection	contributed to the design of the study and oversaw the data collection	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources|Supervision	YES
6371013	30746898	SA	2	led the study	led the study	-	-	NO
6371013	30746898	SM	2	contributed to the design of the study and oversaw the data collection	contributed to the design of the study and oversaw the data collection	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources|Supervision	YES
6371013	30746898	VK	2	contributed to the design of the study and oversaw the data collection	contributed to the design of the study and oversaw the data collection	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources|Supervision	YES
4564581	26413513	Guo-Yi Zhang	2	contributed equally to this work	contributed equally to this work	-	-	NO
4564581	26413513	Yue-Jian Wang	2	contributed equally to this work	contributed equally to this work	-	-	NO
1808424	17375184	BC	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1808424	17375184	BC	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1808424	17375184	CW	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1808424	17375184	JB	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1808424	17375184	JB	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1808424	17375184	NI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1808424	17375184	NI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1808424	17375184	NI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1808424	17375184	NI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1808424	17375184	NI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1808424	17375184	ST	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1808424	17375184	ST	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1808424	17375184	ST	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411055	25915860	EML	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411055	25915860	JJX	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411055	25915860	JJX	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411055	25915860	LDL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4411055	25915860	LDL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411055	25915860	LL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411055	25915860	LYX	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411055	25915860	LYX	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411055	25915860	XDZ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411055	25915860	XDZ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411055	25915860	XDZ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411055	25915860	XDZ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411055	25915860	YMX	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5492679	28662691	AH	2	conceived the project|were involved in the discussion and interpretation of the results	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5492679	28662691	AH	2	conceived the project|were involved in the discussion and interpretation of the results	were involved in the discussion and interpretation of the results	Analyzed the data	Formal analysis	YES
5492679	28662691	All authors	2	were involved in the writing and editing of the manuscript	were involved in the writing and editing of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5492679	28662691	BP	2	provided computataional infrastructure and expertise for the bioinformatics anlayses	provided computataional infrastructure and expertise for the bioinformatics anlayses	-	Formal analysis	YES
5492679	28662691	GL	2	were involved in the discussion and interpretation of the results	were involved in the discussion and interpretation of the results	Analyzed the data	Formal analysis	YES
5492679	28662691	JR	2	were involved the selection of the reference sample and sequencing to generate the assembly	were involved the selection of the reference sample and sequencing to generate the assembly	Performed the experiments	Investigation	YES
5492679	28662691	JS	2	performed the bioinformatics and the comparative analyses	performed the bioinformatics and the comparative analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5492679	28662691	LD	2	conceived the project|were involved the selection of the reference sample and sequencing to generate the assembly	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5492679	28662691	LD	2	conceived the project|were involved the selection of the reference sample and sequencing to generate the assembly	were involved the selection of the reference sample and sequencing to generate the assembly	Performed the experiments	Investigation	YES
5492679	28662691	LK	2	performed the copy number variation and repeat family analyses|wrote the majority of the manuscript	performed the copy number variation and repeat family analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5492679	28662691	LK	2	performed the copy number variation and repeat family analyses|wrote the majority of the manuscript	wrote the majority of the manuscript	Wrote the paper	Writing - Original Draft	YES
5492679	28662691	LO	2	conceived the project|were involved in the discussion and interpretation of the results	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5492679	28662691	LO	2	conceived the project|were involved in the discussion and interpretation of the results	were involved in the discussion and interpretation of the results	Analyzed the data	Formal analysis	YES
5492679	28662691	MS	2	performed the lab work for the reference sample|wrote the majority of the manuscript	performed the lab work for the reference sample	Performed the experiments	Investigation	YES
5492679	28662691	MS	2	performed the lab work for the reference sample|wrote the majority of the manuscript	wrote the majority of the manuscript	Wrote the paper	Writing - Original Draft	YES
5492679	28662691	SG	2	performed the bioinformatics and the comparative analyses|wrote the majority of the manuscript	performed the bioinformatics and the comparative analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5492679	28662691	SG	2	performed the bioinformatics and the comparative analyses|wrote the majority of the manuscript	wrote the majority of the manuscript	Wrote the paper	Writing - Original Draft	YES
5492679	28662691	TG	2	conceived the project|wrote the majority of the manuscript	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5492679	28662691	TG	2	conceived the project|wrote the majority of the manuscript	wrote the majority of the manuscript	Wrote the paper	Writing - Original Draft	YES
5492679	28662691	TMB	2	performed the copy number variation and repeat family analyses	performed the copy number variation and repeat family analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5492679	28662691	TSP	2	provided computataional infrastructure and expertise for the bioinformatics anlayses	provided computataional infrastructure and expertise for the bioinformatics anlayses	-	Formal analysis	YES
3800637	24187522	All authors	2	carried out the proof|conceived of the study, and participated in its design and coordination	carried out the proof	Performed the experiments	Investigation	YES
3800637	24187522	All authors	2	carried out the proof|conceived of the study, and participated in its design and coordination	conceived of the study, and participated in its design and coordination	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
5660992	29118774	AL	PLoS52	conceived and designed the study|analyzed the data	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5660992	29118774	AL	PLoS52	conceived and designed the study|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5660992	29118774	All authors	PLoS52	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5660992	29118774	BM	PLoS52	conceived and designed the study|performed the y2h analysis|performed qrt-pcr analysis|analyzed the data	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5660992	29118774	BM	PLoS52	conceived and designed the study|performed the y2h analysis|performed qrt-pcr analysis|analyzed the data	performed the y2h analysis	Performed the experiments	Investigation	YES
5660992	29118774	BM	PLoS52	conceived and designed the study|performed the y2h analysis|performed qrt-pcr analysis|analyzed the data	performed qrt-pcr analysis	Performed the experiments	Investigation	YES
5660992	29118774	BM	PLoS52	conceived and designed the study|performed the y2h analysis|performed qrt-pcr analysis|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5660992	29118774	DS	PLoS52	performed qrt-pcr analysis	performed qrt-pcr analysis	Performed the experiments	Investigation	YES
5660992	29118774	MJ	PLoS52	conceived and designed the study|performed phylogenetic and bioinformatic analysis|performed the y2h analysis|analyzed the data|wrote the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5660992	29118774	MJ	PLoS52	conceived and designed the study|performed phylogenetic and bioinformatic analysis|performed the y2h analysis|analyzed the data|wrote the manuscript	performed phylogenetic and bioinformatic analysis	Performed the experiments	Formal analysis|Investigation	YES
5660992	29118774	MJ	PLoS52	conceived and designed the study|performed phylogenetic and bioinformatic analysis|performed the y2h analysis|analyzed the data|wrote the manuscript	performed the y2h analysis	Performed the experiments	Investigation	YES
5660992	29118774	MJ	PLoS52	conceived and designed the study|performed phylogenetic and bioinformatic analysis|performed the y2h analysis|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5660992	29118774	MJ	PLoS52	conceived and designed the study|performed phylogenetic and bioinformatic analysis|performed the y2h analysis|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5660992	29118774	MS	PLoS52	performed qrt-pcr analysis	performed qrt-pcr analysis	Performed the experiments	Investigation	YES
3223133	22018096	Farhad Safarpoor Dehkordi	4	statistical analysis and writing of manuscript was done by	statistical analysis and writing of manuscript was done by	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4411056	25915867	AAM	PLoS5	Contributed reagents/materials/analysis tools|Follow-up of seropositve subjects	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411056	25915867	AAM	PLoS5	Contributed reagents/materials/analysis tools|Follow-up of seropositve subjects	Follow-up of seropositve subjects	-	-	NO
4411056	25915867	AF	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411056	25915867	AK	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411056	25915867	AK	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411056	25915867	BAF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411056	25915867	BAF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411056	25915867	BAF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411056	25915867	BAF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411056	25915867	MAT	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411056	25915867	MS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411056	25915867	NM	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411056	25915867	NM	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411056	25915867	RAD	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4411056	25915867	RAD	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1808425	17356702	AY	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1808425	17356702	DP	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1808425	17356702	DP	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1808425	17356702	HL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Discussed experiments and reviewed manuscript	Performed the experiments	Performed the experiments	Investigation	YES
1808425	17356702	HL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Discussed experiments and reviewed manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1808425	17356702	HL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Discussed experiments and reviewed manuscript	Discussed experiments and reviewed manuscript	Wrote the paper	Writing - Review & Editing	YES
1808425	17356702	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1808425	17356702	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1808425	17356702	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1808425	17356702	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1808425	17356702	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1808425	17356702	JW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1808425	17356702	JZ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1808425	17356702	KO	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1808425	17356702	LC	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1808425	17356702	LC	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1808425	17356702	LL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1808425	17356702	NH	PLoS5	Performed the experiments|Analyzed the data|Karyotyping	Performed the experiments	Performed the experiments	Investigation	YES
1808425	17356702	NH	PLoS5	Performed the experiments|Analyzed the data|Karyotyping	Analyzed the data	Analyzed the data	Formal analysis	YES
1808425	17356702	NH	PLoS5	Performed the experiments|Analyzed the data|Karyotyping	Karyotyping	Performed the experiments	Investigation	YES
1808425	17356702	RS	PLoS5	Analyzed the data|Reviewed all the histopathologcial and immunohistotological slides	Analyzed the data	Analyzed the data	Formal analysis	YES
1808425	17356702	RS	PLoS5	Analyzed the data|Reviewed all the histopathologcial and immunohistotological slides	Reviewed all the histopathologcial and immunohistotological slides	Performed the experiments	Investigation	YES
1808425	17356702	SB	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1808425	17356702	SK	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1808425	17356702	TN	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1808425	17356702	WC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1808425	17356702	WD	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1808425	17356702	XL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1808425	17356702	XP	PLoS5	Performed the experiments|Generated precancerous stem cell chimera mice	Performed the experiments	Performed the experiments	Investigation	YES
1808425	17356702	XP	PLoS5	Performed the experiments|Generated precancerous stem cell chimera mice	Generated precancerous stem cell chimera mice	Performed the experiments	Investigation	YES
1808425	17356702	YL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1808425	17356702	YW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1808425	17356702	YY	PLoS5	Performed the experiments|Constructed lentiviral vectors	Performed the experiments	Performed the experiments	Investigation	YES
1808425	17356702	YY	PLoS5	Performed the experiments|Constructed lentiviral vectors	Constructed lentiviral vectors	Performed the experiments	Investigation	YES
6371014	30746864	All	2	authors critically reviewed the first draft of the article and approved the final version to be submitted	authors critically reviewed the first draft of the article and approved the final version to be submitted	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6371014	30746864	DB	2	performed all the laboratory work	performed all the laboratory work	Performed the experiments	Investigation	YES
6371014	30746864	FMJL	2	performed all the laboratory work	performed all the laboratory work	Performed the experiments	Investigation	YES
6371014	30746864	GJD	2	authors critically reviewed the first draft of the article and approved the final version to be submitted	authors critically reviewed the first draft of the article and approved the final version to be submitted	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6371014	30746864	GVM	2	authors critically reviewed the first draft of the article and approved the final version to be submitted	authors critically reviewed the first draft of the article and approved the final version to be submitted	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6371014	30746864	JG	2	authors critically reviewed the first draft of the article and approved the final version to be submitted	authors critically reviewed the first draft of the article and approved the final version to be submitted	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6371014	30746864	MD	2	was the principal investigator of the rampt-c study	was the principal investigator of the rampt-c study	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
6371014	30746864	SRB	2	performed all the laboratory work|had access to the data in the study and takes responsibility for the integrity of the data and the accuracy of the results	performed all the laboratory work	Performed the experiments	Investigation	YES
6371014	30746864	SRB	2	performed all the laboratory work|had access to the data in the study and takes responsibility for the integrity of the data and the accuracy of the results	had access to the data in the study and takes responsibility for the integrity of the data and the accuracy of the results	-	Data curation	YES
6371014	30746864	TLA	2	authors critically reviewed the first draft of the article and approved the final version to be submitted	authors critically reviewed the first draft of the article and approved the final version to be submitted	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5434076	28507230	All authors	PLoS52	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5434076	28507230	E.D.-H.	PLoS52	conceived the research|analysed the data	conceived the research	Conceived and designed the experiments	Conceptualization	YES
5434076	28507230	E.D.-H.	PLoS52	conceived the research|analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
5434076	28507230	H.C.W.	PLoS52	analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
5434076	28507230	K.A.	PLoS52	conceived the research	conceived the research	Conceived and designed the experiments	Conceptualization	YES
5434076	28507230	M.J.C.	PLoS52	analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
5434076	28507230	P.C.	PLoS52	conducted the numerical simulations|analysed the data	conducted the numerical simulations	Performed the experiments	Formal analysis|Investigation	YES
5434076	28507230	P.C.	PLoS52	conducted the numerical simulations|analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
5434076	28507230	R.J.T.	PLoS52	conceived the research|analysed the data	conceived the research	Conceived and designed the experiments	Conceptualization	YES
5434076	28507230	R.J.T.	PLoS52	conceived the research|analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
5434076	28507230	S.G.D.	PLoS52	analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
5434076	28507230	Y.H.	PLoS52	conceived the research|conducted the numerical simulations	conceived the research	Conceived and designed the experiments	Conceptualization	YES
5434076	28507230	Y.H.	PLoS52	conceived the research|conducted the numerical simulations	conducted the numerical simulations	Performed the experiments	Formal analysis|Investigation	YES
5492916	28662630	HK	PLoS52	conducted the experiments	conducted the experiments	Performed the experiments	Investigation	YES
5492916	28662630	JW	PLoS52	designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
5492916	28662630	KO	PLoS52	conducted the experiments|wrote the paper	conducted the experiments	Performed the experiments	Investigation	YES
5492916	28662630	KO	PLoS52	conducted the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5492916	28662630	KS	PLoS52	designed the research|wrote the paper	designed the research	Conceived and designed the experiments	Methodology	YES
5492916	28662630	KS	PLoS52	designed the research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5492916	28662630	MK	PLoS52	conducted the experiments	conducted the experiments	Performed the experiments	Investigation	YES
5492916	28662630	MT	PLoS52	conducted the experiments	conducted the experiments	Performed the experiments	Investigation	YES
5492916	28662630	NY	PLoS52	conducted the experiments	conducted the experiments	Performed the experiments	Investigation	YES
5492916	28662630	TK	PLoS52	designed the research|wrote the paper	designed the research	Conceived and designed the experiments	Methodology	YES
5492916	28662630	TK	PLoS52	designed the research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5660995	29118776	LC	2	designed the experiments and contributed to the data interpretation|undertook the experiment and collected the data	designed the experiments and contributed to the data interpretation	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5660995	29118776	LC	2	designed the experiments and contributed to the data interpretation|undertook the experiment and collected the data	undertook the experiment and collected the data	Performed the experiments	Investigation	YES
5660995	29118776	MS	2	undertook the experiment and collected the data	undertook the experiment and collected the data	Performed the experiments	Investigation	YES
5660995	29118776	R. All	2	authors contributed to the revision of the manuscript and approved the final manuscript	authors contributed to the revision of the manuscript and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5660995	29118776	SA	2	designed the experiments and contributed to the data interpretation	designed the experiments and contributed to the data interpretation	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
4411057	25915898	DDK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411057	25915898	DDK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411057	25915898	DDK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411057	25915898	DDK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411057	25915898	DJM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411057	25915898	DJM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411057	25915898	DJM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411057	25915898	THS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411057	25915898	THS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411057	25915898	THS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1808426	17372626	BV	PLoS5	Provided technical help in microarray work	Provided technical help in microarray work	Performed the experiments	Investigation	YES
1808426	17372626	DX	PLoS5	Conducted computational analyses	Conducted computational analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
1808426	17372626	HN	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1808426	17372626	HN	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1808426	17372626	JQ	PLoS5	Analyzed the data|Conducted statistical analyses and provided critical comments on paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1808426	17372626	JQ	PLoS5	Analyzed the data|Conducted statistical analyses and provided critical comments on paper	Conducted statistical analyses and provided critical comments on paper	Analyzed the data	Formal analysis	YES
1808426	17372626	RK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1808426	17372626	RK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1808426	17372626	RK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1808426	17372626	RK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1808426	17372626	TJ	PLoS5	Analyzed the data|Conducted computational analyses	Analyzed the data	Analyzed the data	Formal analysis	YES
1808426	17372626	TJ	PLoS5	Analyzed the data|Conducted computational analyses	Conducted computational analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4564584	26413500	G. D. Allen	PLoS52	all participated in the inception, planning, and carrying out of the study|wrote the paper	all participated in the inception, planning, and carrying out of the study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4564584	26413500	G. D. Allen	PLoS52	all participated in the inception, planning, and carrying out of the study|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4564584	26413500	Garry W. Auld	PLoS52	all participated in the inception, planning, and carrying out of the study	all participated in the inception, planning, and carrying out of the study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4564584	26413500	Janice I. French	PLoS52	participated in the inception and study design	participated in the inception and study design	Conceived and designed the experiments	Methodology	YES
4564584	26413500	Jennifer E. Anderson	PLoS52	all participated in the inception, planning, and carrying out of the study	all participated in the inception, planning, and carrying out of the study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4564584	26413500	John W. Wilson	PLoS52	participated in statistical planning and analysis of the study results	participated in statistical planning and analysis of the study results	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
4564584	26413500	Marsha Wheeler	PLoS52	were the obstetricians who participated in carrying out the study	were the obstetricians who participated in carrying out the study	Performed the experiments	Investigation	YES
4564584	26413500	Melanie S. Reece	PLoS52	was the clinical research coordinator who participated in carrying out the study	was the clinical research coordinator who participated in carrying out the study	Performed the experiments	Investigation|Project administration	YES
4564584	26413500	Shannon M. Burke	PLoS52	were the obstetricians who participated in carrying out the study	were the obstetricians who participated in carrying out the study	Performed the experiments	Investigation	YES
6376610	30768762	All authors	PLoS52	reviewed and agreed to submit the manuscript	reviewed and agreed to submit the manuscript	Wrote the paper	Writing - Review & Editing	YES
6376610	30768762	CG	PLoS52	completed data collection	completed data collection	Performed the experiments	Investigation	YES
6376610	30768762	DK	PLoS52	designed the study|completed data collection|drafted the manuscript|assisted with interpretation of results	designed the study	Conceived and designed the experiments	Methodology	YES
6376610	30768762	DK	PLoS52	designed the study|completed data collection|drafted the manuscript|assisted with interpretation of results	completed data collection	Performed the experiments	Investigation	YES
6376610	30768762	DK	PLoS52	designed the study|completed data collection|drafted the manuscript|assisted with interpretation of results	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
6376610	30768762	DK	PLoS52	designed the study|completed data collection|drafted the manuscript|assisted with interpretation of results	assisted with interpretation of results	Analyzed the data	Formal analysis	YES
6376610	30768762	JM	PLoS52	assisted with interpretation of results	assisted with interpretation of results	Analyzed the data	Formal analysis	YES
6376610	30768762	KHM	PLoS52	designed the study|assisted with interpretation of results	designed the study	Conceived and designed the experiments	Methodology	YES
6376610	30768762	KHM	PLoS52	designed the study|assisted with interpretation of results	assisted with interpretation of results	Analyzed the data	Formal analysis	YES
6376610	30768762	KL	PLoS52	completed data collection	completed data collection	Performed the experiments	Investigation	YES
6376610	30768762	KM	PLoS52	designed the study|assisted with interpretation of results	designed the study	Conceived and designed the experiments	Methodology	YES
6376610	30768762	KM	PLoS52	designed the study|assisted with interpretation of results	assisted with interpretation of results	Analyzed the data	Formal analysis	YES
6376610	30768762	KMM	PLoS52	designed the study|completed data collection|analysed the data|assisted with interpretation of results	designed the study	Conceived and designed the experiments	Methodology	YES
6376610	30768762	KMM	PLoS52	designed the study|completed data collection|analysed the data|assisted with interpretation of results	completed data collection	Performed the experiments	Investigation	YES
6376610	30768762	KMM	PLoS52	designed the study|completed data collection|analysed the data|assisted with interpretation of results	analysed the data	Analyzed the data	Formal analysis	YES
6376610	30768762	KMM	PLoS52	designed the study|completed data collection|analysed the data|assisted with interpretation of results	assisted with interpretation of results	Analyzed the data	Formal analysis	YES
6376610	30768762	NIH	PLoS52	funded programme	funded programme	-	Funding acquisition	YES
6376610	30768762	VEP	PLoS52	analysed the data|drafted the manuscript|assisted with interpretation of results	analysed the data	Analyzed the data	Formal analysis	YES
6376610	30768762	VEP	PLoS52	analysed the data|drafted the manuscript|assisted with interpretation of results	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
6376610	30768762	VEP	PLoS52	analysed the data|drafted the manuscript|assisted with interpretation of results	assisted with interpretation of results	Analyzed the data	Formal analysis	YES
5492924	28662636	Both authors	2	wrote the paper, read and approved the final manuscript	wrote the paper, read and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5492924	28662636	JT	2	conceived and designed the analysis	conceived and designed the analysis	Conceived and designed the experiments	Conceptualization	YES
5492924	28662636	MCS	2	analysed and interpreted the data	analysed and interpreted the data	Analyzed the data	Formal analysis	YES
4411058	25915420	ADF	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411058	25915420	ADF	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411058	25915420	HL	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411058	25915420	HL	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411058	25915420	JPW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411058	25915420	JPW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411058	25915420	JPW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411058	25915420	KK	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411058	25915420	KK	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411058	25915420	MM	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411058	25915420	MM	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411058	25915420	MSK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411058	25915420	MSK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411058	25915420	MSK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411058	25915420	MW	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411058	25915420	MW	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411058	25915420	RO	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411058	25915420	RO	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5434078	28507232	M.O.	2	provided algorithms and discussed theoretical aspects of the manuscript	provided algorithms and discussed theoretical aspects of the manuscript	Contributed reagents/materials/analysis tools	Formal analysis|Software	YES
5434078	28507232	N.M.	2	conceived of and designed the study|drafted the manuscript	conceived of and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5434078	28507232	N.M.	2	conceived of and designed the study|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5434078	28507232	T.E.	2	carried out the numerical experiments and performed the data analysis|drafted the manuscript	carried out the numerical experiments and performed the data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5434078	28507232	T.E.	2	carried out the numerical experiments and performed the data analysis|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5434078	28507232	T.W.	2	preprocessed the fmri data|drafted the manuscript	preprocessed the fmri data	Analyzed the data	Data curation	YES
5434078	28507232	T.W.	2	preprocessed the fmri data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
1808427	17372629	BN	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1808427	17372629	BN	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1808427	17372629	BN	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1808427	17372629	PR	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6376611	30768776	All authors	2	contributed to the writing of the manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
6376611	30768776	CHO	2	provided socio-cultural expertise for the study	provided socio-cultural expertise for the study	-	-	NO
6376611	30768776	CWH	2	provided network laboratory oversight for data collection, testing, and reporting of the pharmacologic measures and technologies for the study	provided network laboratory oversight for data collection, testing, and reporting of the pharmacologic measures and technologies for the study	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources|Supervision	YES
6376611	30768776	DPW	2	provided scientific leadership in the conceptualization, development and implementation of the study	provided scientific leadership in the conceptualization, development and implementation of the study	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Supervision	YES
6376611	30768776	EPM	2	provided network laboratory oversight for data collection, testing, and reporting of the pharmacologic measures and technologies for the study	provided network laboratory oversight for data collection, testing, and reporting of the pharmacologic measures and technologies for the study	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources|Supervision	YES
6376611	30768776	GB	2	were the protocol statisticians and provided statistical design, data monitoring and analysis for the study	were the protocol statisticians and provided statistical design, data monitoring and analysis for the study	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Methodology|Resources|Supervision	YES
6376611	30768776	IK	2	provided research, data analysis and interpretation for the study and was also a co-pi for her respective site	provided research, data analysis and interpretation for the study and was also a co-pi for her respective site	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6376611	30768776	JPL	2	provided scientific leadership in all phases of community engagement for the study	provided scientific leadership in all phases of community engagement for the study	-	Supervision	YES
6376611	30768776	KHM	2	provided scientific leadership in the conceptualization, development and implementation of the study|served as a protocol team member and provided scientific medical and health-related expertise for the study	provided scientific leadership in the conceptualization, development and implementation of the study	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Supervision	YES
6376611	30768776	KHM	2	provided scientific leadership in the conceptualization, development and implementation of the study|served as a protocol team member and provided scientific medical and health-related expertise for the study	served as a protocol team member and provided scientific medical and health-related expertise for the study	Conceived and designed the experiments	Methodology	YES
6376611	30768776	LEN	2	was the lead implementation scientist for the study|provided scientific leadership in the conceptualization, development and implementation of the study	was the lead implementation scientist for the study	Performed the experiments	Investigation	YES
6376611	30768776	LEN	2	was the lead implementation scientist for the study|provided scientific leadership in the conceptualization, development and implementation of the study	provided scientific leadership in the conceptualization, development and implementation of the study	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Supervision	YES
6376611	30768776	LHW	2	were the site investigators for the study in their respective cities|provided scientific leadership in the conceptualization, development and implementation of the study	were the site investigators for the study in their respective cities	-	-	NO
6376611	30768776	LHW	2	were the site investigators for the study in their respective cities|provided scientific leadership in the conceptualization, development and implementation of the study	provided scientific leadership in the conceptualization, development and implementation of the study	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Supervision	YES
6376611	30768776	LME	2	supervised data management for the study	supervised data management for the study	Analyzed the data	Data curation|Project administration|Supervision	YES
6376611	30768776	LW	2	provided scientific leadership in the conceptualization, development and implementation of the study	provided scientific leadership in the conceptualization, development and implementation of the study	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Supervision	YES
6376611	30768776	MM	2	were the site investigators for the study in their respective cities|provided scientific leadership in the conceptualization, development and implementation of the study	were the site investigators for the study in their respective cities	-	-	NO
6376611	30768776	MM	2	were the site investigators for the study in their respective cities|provided scientific leadership in the conceptualization, development and implementation of the study	provided scientific leadership in the conceptualization, development and implementation of the study	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Supervision	YES
6376611	30768776	PW	2	provided project administration support for the study	provided project administration support for the study	-	Project administration	YES
6376611	30768776	SDF	2	was the co-chair of the study|provided scientific leadership in the conceptualization, development and implementation of the study	was the co-chair of the study	-	-	NO
6376611	30768776	SDF	2	was the co-chair of the study|provided scientific leadership in the conceptualization, development and implementation of the study	provided scientific leadership in the conceptualization, development and implementation of the study	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Supervision	YES
6376611	30768776	SS	2	were the site investigators for the study in their respective cities|provided scientific leadership in the conceptualization, development and implementation of the study	were the site investigators for the study in their respective cities	-	-	NO
6376611	30768776	SS	2	were the site investigators for the study in their respective cities|provided scientific leadership in the conceptualization, development and implementation of the study	provided scientific leadership in the conceptualization, development and implementation of the study	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Supervision	YES
6376611	30768776	YQC	2	were the protocol statisticians and provided statistical design, data monitoring and analysis for the study	were the protocol statisticians and provided statistical design, data monitoring and analysis for the study	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Methodology|Resources|Supervision	YES
5661020	29118777	AA	PLoS52	made some corrections and additional contributions	made some corrections and additional contributions	-	-	NO
5661020	29118777	LC	PLoS52	made some corrections and additional contributions	made some corrections and additional contributions	-	-	NO
5661020	29118777	LR	PLoS52	made some corrections and additional contributions	made some corrections and additional contributions	-	-	NO
5661020	29118777	ME	PLoS52	made some corrections and additional contributions	made some corrections and additional contributions	-	-	NO
5661020	29118777	NO	PLoS52	made some corrections and additional contributions	made some corrections and additional contributions	-	-	NO
5661020	29118777	SC	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3382959	22745639	C. Busu	2	contributed equally	contributed equally	-	-	NO
3382959	22745639	W. Li	2	contributed equally	contributed equally	-	-	NO
5493002	28662633	DD	2	contributed to statistical analysis of data and manuscript preparation	contributed to statistical analysis of data and manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5493002	28662633	ET	2	contributed to the experimental design, all aspects of execution, data analysis and manuscript preparation and funding	contributed to the experimental design, all aspects of execution, data analysis and manuscript preparation and funding	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Funding acquisition|Investigation|Methodology|Resources|Writing - Original Draft	YES
5493002	28662633	KB	2	contributed to experimental design of ozone treatments, ozone rating and manuscript preparation	contributed to experimental design of ozone treatments, ozone rating and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5493002	28662633	NW	2	contributed to the experimental design, all aspects of execution, data analysis and manuscript preparation	contributed to the experimental design, all aspects of execution, data analysis and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
5493002	28662633	TC	2	contributed to experimental design and manuscript preparation and funding	contributed to experimental design and manuscript preparation and funding	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Funding acquisition|Investigation|Methodology|Writing - Original Draft	YES
6376800	30768753	DCH	2	drafted the letter	drafted the letter	Wrote the paper	Writing - Original Draft	YES
6376800	30768753	JWM	2	drafted the letter	drafted the letter	Wrote the paper	Writing - Original Draft	YES
4411059	25915050	BH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Data construction	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411059	25915050	BH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Data construction	Analyzed the data	Analyzed the data	Formal analysis	YES
4411059	25915050	BH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Data construction	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411059	25915050	BH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Data construction	Data construction	Performed the experiments	Investigation	YES
4411059	25915050	CH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Data construction	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411059	25915050	CH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Data construction	Analyzed the data	Analyzed the data	Formal analysis	YES
4411059	25915050	CH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Data construction	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411059	25915050	CH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Data construction	Data construction	Performed the experiments	Investigation	YES
4411059	25915050	MA	PLoS5	Conceived and designed the experiments|Data construction	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411059	25915050	MA	PLoS5	Conceived and designed the experiments|Data construction	Data construction	Performed the experiments	Investigation	YES
5434080	28507234	All authors	2	discussed the results and approved the manuscript	discussed the results and approved the manuscript	-	-	NO
5434080	28507234	E.B.	2	devised the topic|carried out the simulations and drafted most of the manuscript	devised the topic	Conceived and designed the experiments	Conceptualization	YES
5434080	28507234	E.B.	2	devised the topic|carried out the simulations and drafted most of the manuscript	carried out the simulations and drafted most of the manuscript	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5434080	28507234	U.P.	2	devised the topic	devised the topic	Conceived and designed the experiments	Conceptualization	YES
1808428	17372628	HH	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1808428	17372628	JK	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1808428	17372628	LL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1808428	17372628	LL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1808428	17372628	LL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1808428	17372628	LL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1808428	17372628	MG	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1808428	17372628	PR	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1808428	17372628	RC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1808428	17372628	RS	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1808428	17372628	VS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1808428	17372628	VS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1808428	17372628	WD	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1808428	17372628	WT	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1808428	17372628	XC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1808428	17372628	XD	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1808428	17372628	XD	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1808428	17372628	XW	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5914294	29732052	H.-M.M.	2	performed iscat imaging experiment	performed iscat imaging experiment	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
5914294	29732052	I.-B.L.	2	contributed to this work equally|performed iscat imaging experiment	contributed to this work equally	-	-	NO
5914294	29732052	I.-B.L.	2	contributed to this work equally|performed iscat imaging experiment	performed iscat imaging experiment	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
5914294	29732052	J.-H.J.	2	performed iscat imaging experiment	performed iscat imaging experiment	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
5914294	29732052	J.-S.P.	2	prepared live cells|contributed to this work equally|performed iscat imaging experiment	prepared live cells	Performed the experiments	Investigation	YES
5914294	29732052	J.-S.P.	2	prepared live cells|contributed to this work equally|performed iscat imaging experiment	contributed to this work equally	-	-	NO
5914294	29732052	J.-S.P.	2	prepared live cells|contributed to this work equally|performed iscat imaging experiment	performed iscat imaging experiment	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
5914294	29732052	K.-H.K.	2	performed iscat imaging experiment	performed iscat imaging experiment	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
5914294	29732052	M.C.	2	proposed the concept and designed the experiment|led the project	proposed the concept and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5914294	29732052	M.C.	2	proposed the concept and designed the experiment|led the project	led the project	-	-	NO
5914294	29732052	S.-C.H.	2	proposed the concept and designed the experiment|contributed to the writing	proposed the concept and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5914294	29732052	S.-C.H.	2	proposed the concept and designed the experiment|contributed to the writing	contributed to the writing	Wrote the paper	-	YES
6378757	30775846	AD	2	designed and implemented the study|contributed to the interpretation and presentation of the findings	designed and implemented the study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6378757	30775846	AD	2	designed and implemented the study|contributed to the interpretation and presentation of the findings	contributed to the interpretation and presentation of the findings	Analyzed the data	Formal analysis	YES
6378757	30775846	AJS	2	designed and implemented the study|drafted the manuscript|contributed to the interpretation and presentation of the findings	designed and implemented the study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6378757	30775846	AJS	2	designed and implemented the study|drafted the manuscript|contributed to the interpretation and presentation of the findings	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
6378757	30775846	AJS	2	designed and implemented the study|drafted the manuscript|contributed to the interpretation and presentation of the findings	contributed to the interpretation and presentation of the findings	Analyzed the data	Formal analysis	YES
6378757	30775846	HK	2	designed and implemented the study|contributed to the interpretation and presentation of the findings	designed and implemented the study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6378757	30775846	HK	2	designed and implemented the study|contributed to the interpretation and presentation of the findings	contributed to the interpretation and presentation of the findings	Analyzed the data	Formal analysis	YES
6378757	30775846	KCC	2	designed and implemented the study|drafted the manuscript|contributed to the interpretation and presentation of the findings	designed and implemented the study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6378757	30775846	KCC	2	designed and implemented the study|drafted the manuscript|contributed to the interpretation and presentation of the findings	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
6378757	30775846	KCC	2	designed and implemented the study|drafted the manuscript|contributed to the interpretation and presentation of the findings	contributed to the interpretation and presentation of the findings	Analyzed the data	Formal analysis	YES
6378757	30775846	RH	2	designed and implemented the study|contributed to the interpretation and presentation of the findings	designed and implemented the study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6378757	30775846	RH	2	designed and implemented the study|contributed to the interpretation and presentation of the findings	contributed to the interpretation and presentation of the findings	Analyzed the data	Formal analysis	YES
5661024	29118779	JL	PLoS52	designed the experiment, drafted the manuscript	designed the experiment, drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5661024	29118779	JX	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5661024	29118779	ML	PLoS52	contributed reagents and analysis tools	contributed reagents and analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5661024	29118779	NC	PLoS52	contributed reagents and analysis tools	contributed reagents and analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5661024	29118779	SZ	PLoS52	contributed reagents and analysis tools	contributed reagents and analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5661024	29118779	YC	PLoS52	collected samples and performed the experiment	collected samples and performed the experiment	Performed the experiments	Investigation	YES
5661024	29118779	YS	PLoS52	designed the experiment, drafted the manuscript|analyzed the data	designed the experiment, drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5661024	29118779	YS	PLoS52	designed the experiment, drafted the manuscript|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
4411060	25915063	ADD	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411060	25915063	ADD	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411060	25915063	AP	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411060	25915063	AP	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411060	25915063	AP	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411060	25915063	AP	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411060	25915063	CDC	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411060	25915063	CDC	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411060	25915063	CS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411060	25915063	CS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4411060	25915063	CS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4411060	25915063	EN	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411060	25915063	EN	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411060	25915063	EN	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411060	25915063	EP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4411060	25915063	EP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411060	25915063	FDL	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4411060	25915063	FDL	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4411060	25915063	GD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411060	25915063	GD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4411060	25915063	GD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4411060	25915063	VI	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411060	25915063	VI	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411060	25915063	VI	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6381287	30784216	HS	2	is responsible for all the entirety of the piece	is responsible for all the entirety of the piece	-	-	NO
5661064	29118780	All authors	2	listed have made a substantial, direct and intellectual contribution to the work, and approved it for publication	listed have made a substantial, direct and intellectual contribution to the work, and approved it for publication	-	-	NO
5661064	29118780	The authors	2	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	Performed the experiments	Investigation	YES
5493111	28666414	AOP	2	carried out the analysis of the data	carried out the analysis of the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5493111	28666414	ATS	2	performed the laboratory analyses	performed the laboratory analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5493111	28666414	CCS	2	performed the laboratory analyses	performed the laboratory analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5493111	28666414	DMRP	2	carried out the analysis of the data|draft the manuscript	carried out the analysis of the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5493111	28666414	DMRP	2	carried out the analysis of the data|draft the manuscript	draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5493111	28666414	ESS	2	carried out the analysis of the data	carried out the analysis of the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5493111	28666414	GHG	2	planned the experiments	planned the experiments	Conceived and designed the experiments	Conceptualization	YES
5493111	28666414	GKZ	2	performed the laboratory analyses	performed the laboratory analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5493111	28666414	GPB	2	performed the laboratory analyses|carried out the analysis of the data|draft the manuscript	performed the laboratory analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5493111	28666414	GPB	2	performed the laboratory analyses|carried out the analysis of the data|draft the manuscript	carried out the analysis of the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5493111	28666414	GPB	2	performed the laboratory analyses|carried out the analysis of the data|draft the manuscript	draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5493111	28666414	JVCO	2	planned the experiments|carried out the analysis of the data|draft the manuscript	planned the experiments	Conceived and designed the experiments	Conceptualization	YES
5493111	28666414	JVCO	2	planned the experiments|carried out the analysis of the data|draft the manuscript	carried out the analysis of the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5493111	28666414	JVCO	2	planned the experiments|carried out the analysis of the data|draft the manuscript	draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5493111	28666414	RACS	2	carried out the analysis of the data	carried out the analysis of the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5493111	28666414	RMMTSD	2	carried out the analysis of the data	carried out the analysis of the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3274447	22104600	NVG	1	Chemical isolation and structural elucidation	Chemical isolation and structural elucidation	Performed the experiments	Investigation	YES
3274447	22104600	PDM	1	Chemical isolation and structural elucidation	Chemical isolation and structural elucidation	Performed the experiments	Investigation	YES
3274447	22104600	RAV	1	Chemical isolation and structural elucidation	Chemical isolation and structural elucidation	Performed the experiments	Investigation	YES
4411061	25915929	AMZ	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411061	25915929	BG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411061	25915929	BG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411061	25915929	BG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411061	25915929	JRF	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411061	25915929	MAW	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411061	25915929	MAW	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411061	25915929	MAW	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411061	25915929	MAW	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411061	25915929	MBR	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411061	25915929	QYZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411061	25915929	QYZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411061	25915929	QYZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411061	25915929	SES	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411061	25915929	SES	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411061	25915929	SES	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1808429	17356703	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1808429	17356703	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1808429	17356703	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1808429	17356703	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1808429	17356703	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1808429	17356703	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1808429	17356703	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1808429	17356703	PR	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1808429	17356703	PR	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6389354	30803162	AA	2	contributed data for the analysis	contributed data for the analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6389354	30803162	AJ	2	contributed to the concept development|performed the statistical analysis	contributed to the concept development	Conceived and designed the experiments	Conceptualization	YES
6389354	30803162	AJ	2	contributed to the concept development|performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
6389354	30803162	AK	2	contributed data for the analysis	contributed data for the analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6389354	30803162	All authors	2	commented on the draft manuscript and approved of the final manuscript	commented on the draft manuscript and approved of the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6389354	30803162	BLHS	2	contributed data for the analysis	contributed data for the analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6389354	30803162	EY	2	contributed data for the analysis	contributed data for the analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6389354	30803162	FJ	2	contributed data for the analysis	contributed data for the analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6389354	30803162	JT	2	contributed data for the analysis	contributed data for the analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6389354	30803162	JYC	2	contributed to the concept development|contributed data for the analysis	contributed to the concept development	Conceived and designed the experiments	Conceptualization	YES
6389354	30803162	JYC	2	contributed to the concept development|contributed data for the analysis	contributed data for the analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6389354	30803162	KVN	2	contributed data for the analysis	contributed data for the analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6389354	30803162	MPL	2	contributed data for the analysis	contributed data for the analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6389354	30803162	MYA	2	contributed to the concept development|wrote the first draft of the manuscript	contributed to the concept development	Conceived and designed the experiments	Conceptualization	YES
6389354	30803162	MYA	2	contributed to the concept development|wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
6389354	30803162	NK	2	contributed data for the analysis	contributed data for the analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6389354	30803162	OTN	2	contributed data for the analysis	contributed data for the analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6389354	30803162	RC	2	contributed data for the analysis	contributed data for the analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6389354	30803162	RD	2	contributed data for the analysis	contributed data for the analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6389354	30803162	SK	2	contributed data for the analysis|contributed data for the analysis	contributed data for the analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6389354	30803162	SK	2	contributed data for the analysis|contributed data for the analysis	contributed data for the analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6389354	30803162	SP	2	contributed data for the analysis	contributed data for the analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6389354	30803162	TPM	2	contributed data for the analysis	contributed data for the analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6389354	30803162	TTP	2	contributed data for the analysis	contributed data for the analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6389354	30803162	VK	2	contributed data for the analysis	contributed data for the analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6389354	30803162	WR	2	contributed data for the analysis	contributed data for the analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6389354	30803162	WWW	2	contributed data for the analysis	contributed data for the analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5661082	29118775	FN	7	Conducting the experiments|Analyzing the data|Writing the manuscript	Conducting the experiments	Performed the experiments	Investigation	YES
5661082	29118775	FN	7	Conducting the experiments|Analyzing the data|Writing the manuscript	Analyzing the data	Analyzed the data	Formal analysis	YES
5661082	29118775	FN	7	Conducting the experiments|Analyzing the data|Writing the manuscript	Writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5661082	29118775	HY	7	Revising the manuscript	Revising the manuscript	Wrote the paper	Writing - Review & Editing	YES
5661082	29118775	HZ	7	Conducting the experiments	Conducting the experiments	Performed the experiments	Investigation	YES
5661082	29118775	LJN	7	Conducting the experiments	Conducting the experiments	Performed the experiments	Investigation	YES
5661082	29118775	WW	7	Conceiving the study|Analyzing the data|Writing the manuscript|Revising the manuscript	Conceiving the study	Conceived and designed the experiments	Conceptualization	YES
5661082	29118775	WW	7	Conceiving the study|Analyzing the data|Writing the manuscript|Revising the manuscript	Analyzing the data	Analyzed the data	Formal analysis	YES
5661082	29118775	WW	7	Conceiving the study|Analyzing the data|Writing the manuscript|Revising the manuscript	Writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5661082	29118775	WW	7	Conceiving the study|Analyzing the data|Writing the manuscript|Revising the manuscript	Revising the manuscript	Wrote the paper	Writing - Review & Editing	YES
5661082	29118775	XLW	7	Analyzing the data|Revising the manuscript	Analyzing the data	Analyzed the data	Formal analysis	YES
5661082	29118775	XLW	7	Analyzing the data|Revising the manuscript	Revising the manuscript	Wrote the paper	Writing - Review & Editing	YES
5661082	29118775	ZKW	7	Revising the manuscript	Revising the manuscript	Wrote the paper	Writing - Review & Editing	YES
1808430	17356704	AS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1808430	17356704	OB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1808430	17356704	OB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1808430	17356704	OB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1808430	17356704	SP	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1808430	17356704	TG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1808430	17356704	TG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1808430	17356704	TG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1808430	17356704	TG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5493846	28666407	AB	2	designed and supervised cell culture experiments and analyzed the respective data	designed and supervised cell culture experiments and analyzed the respective data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology|Supervision	YES
5493846	28666407	AH-O	2	performed biochemical experiments, designed bioinformatic analyses, developed computational data and analyzed all data	performed biochemical experiments, designed bioinformatic analyses, developed computational data and analyzed all data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5493846	28666407	AP	2	designed bioinformatic analyses, developed and analyzed computational data	designed bioinformatic analyses, developed and analyzed computational data	Conceived and designed the experiments|Analyzed the data	Formal analysis	YES
5493846	28666407	AZ	2	designed and performed next generation sequencing	designed and performed next generation sequencing	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5493846	28666407	LB	2	designed and performed cell culture experiments and analyzed the respective data	designed and performed cell culture experiments and analyzed the respective data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5493846	28666407	MF	2	conceived and supervised the overall study, designed the experiments and analyzed all data|was responsible for the final version of the paper	conceived and supervised the overall study, designed the experiments and analyzed all data	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology|Supervision	YES
5493846	28666407	MF	2	conceived and supervised the overall study, designed the experiments and analyzed all data|was responsible for the final version of the paper	was responsible for the final version of the paper	-	-	NO
5493846	28666407	PJ	2	conceived and planned the overall study, designed all experiments and bioinformatic analyses, performed initial biochemical experiments and analyzed all data|drafted the manuscript with input from all authors and participated in preparation of its final version	conceived and planned the overall study, designed all experiments and bioinformatic analyses, performed initial biochemical experiments and analyzed all data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation|Methodology	YES
5493846	28666407	PJ	2	conceived and planned the overall study, designed all experiments and bioinformatic analyses, performed initial biochemical experiments and analyzed all data|drafted the manuscript with input from all authors and participated in preparation of its final version	drafted the manuscript with input from all authors and participated in preparation of its final version	Wrote the paper	Writing - Original Draft	YES
5493846	28666407	PM	2	participated in cell culture experiments	participated in cell culture experiments	Performed the experiments	Investigation	YES
4411062	25915948	HF	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4411062	25915948	HF	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411062	25915948	HR	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4411062	25915948	HR	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411062	25915948	JJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411062	25915948	JJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411062	25915948	JJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411062	25915948	JJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411062	25915948	JJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411062	25915948	NNL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411062	25915948	NNL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411062	25915948	NNL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411062	25915948	NNL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411062	25915948	SLW	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4411062	25915948	SLW	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411062	25915948	WHW	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4411062	25915948	WHW	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411062	25915948	XFL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4411062	25915948	XFL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411062	25915948	YPL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4411062	25915948	YPL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411062	25915948	YWS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4411062	25915948	YWS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411062	25915948	YXL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411062	25915948	YXL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411062	25915948	YXL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411062	25915948	YXL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411062	25915948	YXL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411062	25915948	ZHY	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4411062	25915948	ZHY	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5454228	28554979	A.I.	5	contributed dialogue and expertise on extraterrestrial samples ( Stardust	contributed dialogue and expertise on extraterrestrial samples ( Stardust	Contributed reagents/materials/analysis tools	Resources	YES
5454228	28554979	D.H.W.	5	led the discussion and presented the talk at the meeting Cometary Science After Rosetta|had more learning to do about Stardust and chondrules and received tutoring from co-authors H	led the discussion and presented the talk at the meeting Cometary Science After Rosetta	-	-	NO
5454228	28554979	D.H.W.	5	led the discussion and presented the talk at the meeting Cometary Science After Rosetta|had more learning to do about Stardust and chondrules and received tutoring from co-authors H	had more learning to do about Stardust and chondrules and received tutoring from co-authors H	-	-	NO
5454228	28554979	H.A.I.	5	contributed dialogue and expertise on extraterrestrial samples ( Stardust	contributed dialogue and expertise on extraterrestrial samples ( Stardust	Contributed reagents/materials/analysis tools	Resources	YES
5454228	28554979	M.E.Z.	5	contributed dialogue and expertise on extraterrestrial samples ( Stardust|contributed dialog and expertise on the fe-mn relation	contributed dialogue and expertise on extraterrestrial samples ( Stardust	Contributed reagents/materials/analysis tools	Resources	YES
5454228	28554979	M.E.Z.	5	contributed dialogue and expertise on extraterrestrial samples ( Stardust|contributed dialog and expertise on the fe-mn relation	contributed dialog and expertise on the fe-mn relation	-	-	NO
6393855	30816632	All	2	authors contributed to the final version of the manuscript	authors contributed to the final version of the manuscript	-	-	NO
6393855	30816632	CN	2	performed the research	performed the research	Performed the experiments	Investigation	YES
6393855	30816632	ERB	2	performed the research|designed the research study	performed the research	Performed the experiments	Investigation	YES
6393855	30816632	ERB	2	performed the research|designed the research study	designed the research study	Conceived and designed the experiments	Methodology	YES
6393855	30816632	FMK	2	performed the research	performed the research	Performed the experiments	Investigation	YES
6393855	30816632	GN	2	performed the research	performed the research	Performed the experiments	Investigation	YES
6393855	30816632	JMB	2	performed the research|designed the research study|authors contributed to the final version of the manuscript	performed the research	Performed the experiments	Investigation	YES
6393855	30816632	JMB	2	performed the research|designed the research study|authors contributed to the final version of the manuscript	designed the research study	Conceived and designed the experiments	Methodology	YES
6393855	30816632	JMB	2	performed the research|designed the research study|authors contributed to the final version of the manuscript	authors contributed to the final version of the manuscript	-	-	NO
6393855	30816632	NC	2	performed the research	performed the research	Performed the experiments	Investigation	YES
6393855	30816632	NM	2	performed the research	performed the research	Performed the experiments	Investigation	YES
6393855	30816632	SLH	2	performed the research|designed the research study	performed the research	Performed the experiments	Investigation	YES
6393855	30816632	SLH	2	performed the research|designed the research study	designed the research study	Conceived and designed the experiments	Methodology	YES
6393855	30816632	TPP	2	performed the research|designed the research study	performed the research	Performed the experiments	Investigation	YES
6393855	30816632	TPP	2	performed the research|designed the research study	designed the research study	Conceived and designed the experiments	Methodology	YES
5661169	29118778	AP	PLoS52	conceived and designed the experiments|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5661169	29118778	AP	PLoS52	conceived and designed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5661169	29118778	BW	PLoS52	analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5661169	29118778	BW	PLoS52	analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5661169	29118778	DJ	PLoS52	oversaw fiber analysis	oversaw fiber analysis	-	Supervision	YES
5661169	29118778	LS	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5661169	29118778	PC	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5661169	29118778	TS	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5661169	29118778	XD	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
1808431	17375185	EB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1808431	17375185	EB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1808431	17375185	EB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1808431	17375185	EB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1808431	17375185	EB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1808431	17375185	XH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1808431	17375185	XH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1808431	17375185	XH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1808431	17375185	XH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1808431	17375185	XH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3804371	24191141	A. T. Pinheiro	PLoS52	were responsible for recruiting and clinical evaluation of patients	were responsible for recruiting and clinical evaluation of patients	Performed the experiments	Investigation	YES
3804371	24191141	Carisi A. Polanczyk	PLoS52	reviewed the paper	reviewed the paper	Wrote the paper	Writing - Review & Editing	YES
3804371	24191141	Eduardo Sprinz	PLoS52	were joint senior authors on this work|wrote the paper	were joint senior authors on this work	-	-	NO
3804371	24191141	Eduardo Sprinz	PLoS52	were joint senior authors on this work|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3804371	24191141	M. Sassi	PLoS52	genotyped the patients and performed the experiments	genotyped the patients and performed the experiments	Performed the experiments	Investigation	YES
3804371	24191141	Mariangela F. Silveira	PLoS52	were responsible for recruiting and clinical evaluation of patients	were responsible for recruiting and clinical evaluation of patients	Performed the experiments	Investigation	YES
3804371	24191141	Rosmeri K. Lazzaretti	PLoS52	performed the statistical analyses|wrote the paper	performed the statistical analyses	Analyzed the data	Formal analysis	YES
3804371	24191141	Rosmeri K. Lazzaretti	PLoS52	performed the statistical analyses|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3804371	24191141	Vanessa S. Mattevi	PLoS52	were joint senior authors on this work|conceived and designed the experiments|performed the statistical analyses|wrote the paper	were joint senior authors on this work	-	-	NO
3804371	24191141	Vanessa S. Mattevi	PLoS52	were joint senior authors on this work|conceived and designed the experiments|performed the statistical analyses|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
3804371	24191141	Vanessa S. Mattevi	PLoS52	were joint senior authors on this work|conceived and designed the experiments|performed the statistical analyses|wrote the paper	performed the statistical analyses	Analyzed the data	Formal analysis	YES
3804371	24191141	Vanessa S. Mattevi	PLoS52	were joint senior authors on this work|conceived and designed the experiments|performed the statistical analyses|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411063	25915935	EH	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4411063	25915935	EH	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4411063	25915935	FA	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4411063	25915935	FA	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4411063	25915935	HH	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4411063	25915935	HH	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4411063	25915935	HY	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411063	25915935	HY	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411063	25915935	HY	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411063	25915935	MH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411063	25915935	MH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411063	25915935	MH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411063	25915935	MH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411063	25915935	NH	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411063	25915935	TM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411063	25915935	TM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411063	25915935	TM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3279308	22196374	AJM	2	are responsible for supervision and rationale of all experiments	are responsible for supervision and rationale of all experiments	Performed the experiments	Investigation|Supervision	YES
3279308	22196374	BMD	2	carried out the dna extraction and 16s rrna gene libraries	carried out the dna extraction and 16s rrna gene libraries	Performed the experiments	Investigation	YES
3279308	22196374	CFFA	2	carried out the biodegradation experiments, microorganism isolation, hydrocarbon analyses and drafted the manuscript	carried out the biodegradation experiments, microorganism isolation, hydrocarbon analyses and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3279308	22196374	EVSN	2	provided the petroleum samples|are responsible for supervision and rationale of all experiments	provided the petroleum samples	Contributed reagents/materials/analysis tools	Resources	YES
3279308	22196374	EVSN	2	provided the petroleum samples|are responsible for supervision and rationale of all experiments	are responsible for supervision and rationale of all experiments	Performed the experiments	Investigation|Supervision	YES
3279308	22196374	GFC	2	carried out the biodegradation experiments, microorganism isolation, hydrocarbon analyses and drafted the manuscript	carried out the biodegradation experiments, microorganism isolation, hydrocarbon analyses and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3279308	22196374	INSG	2	carried out the dna extraction and 16s rrna gene libraries	carried out the dna extraction and 16s rrna gene libraries	Performed the experiments	Investigation	YES
3279308	22196374	SPV	2	carried out the dna extraction and 16s rrna gene libraries	carried out the dna extraction and 16s rrna gene libraries	Performed the experiments	Investigation	YES
3279308	22196374	VMO	2	are responsible for supervision and rationale of all experiments	are responsible for supervision and rationale of all experiments	Performed the experiments	Investigation|Supervision	YES
5494133	28668094	APL	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5494133	28668094	CHL	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5494133	28668094	CJC	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5494133	28668094	CYL	PLoS52	conceived and designed the experiments|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5494133	28668094	CYL	PLoS52	conceived and designed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5494133	28668094	JML	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5494133	28668094	TX	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5494133	28668094	YHH	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5494133	28668094	YQD	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5454230	28554981	M.G.G.T.T.	2	was the primary author	was the primary author	Wrote the paper	Writing - Original Draft	YES
5454230	28554981	N.A.	2	who also aided with the construction and provision of figures	who also aided with the construction and provision of figures	Performed the experiments	Investigation|Visualization	YES
6416473	30868739	Brooke Hoots	2	curated the nhbs data|conducted the main nhbs data analysis	curated the nhbs data	Analyzed the data	Data curation	YES
6416473	30868739	Brooke Hoots	2	curated the nhbs data|conducted the main nhbs data analysis	conducted the main nhbs data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6416473	30868739	Chris Beyrer	2	contributed to study conceptualization|reviewed and edited the manuscript	contributed to study conceptualization	Conceived and designed the experiments	Conceptualization	YES
6416473	30868739	Chris Beyrer	2	contributed to study conceptualization|reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
6416473	30868739	Colin Flynn	2	contributed to other data analyses	contributed to other data analyses	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6416473	30868739	Danielle German	2	contributed to other data analyses	contributed to other data analyses	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6416473	30868739	Dobromir Dimitrov	2	designed the modelling methodology	designed the modelling methodology	Conceived and designed the experiments|Performed the experiments	Methodology	YES
6416473	30868739	Gabriela Paz-Bailey	2	curated the nhbs data|contributed to other data analyses|reviewed and edited the manuscript	curated the nhbs data	Analyzed the data	Data curation	YES
6416473	30868739	Gabriela Paz-Bailey	2	curated the nhbs data|contributed to other data analyses|reviewed and edited the manuscript	contributed to other data analyses	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6416473	30868739	Gabriela Paz-Bailey	2	curated the nhbs data|contributed to other data analyses|reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
6416473	30868739	H Remien	2	contributed to study conceptualization|acquired funding|reviewed and edited the manuscript	contributed to study conceptualization	Conceived and designed the experiments	Conceptualization	YES
6416473	30868739	H Remien	2	contributed to study conceptualization|acquired funding|reviewed and edited the manuscript	acquired funding	-	Funding acquisition	YES
6416473	30868739	H Remien	2	contributed to study conceptualization|acquired funding|reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
6416473	30868739	Jason E. Farley	2	contributed to other data analyses	contributed to other data analyses	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6416473	30868739	M Mitchell	2	contributed to other data analyses|designed the modelling methodology|developed the model code|wrote the initial draft of the manuscript	contributed to other data analyses	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6416473	30868739	M Mitchell	2	contributed to other data analyses|designed the modelling methodology|developed the model code|wrote the initial draft of the manuscript	designed the modelling methodology	Conceived and designed the experiments|Performed the experiments	Methodology	YES
6416473	30868739	M Mitchell	2	contributed to other data analyses|designed the modelling methodology|developed the model code|wrote the initial draft of the manuscript	developed the model code	Performed the experiments	Methodology|Software	YES
6416473	30868739	M Mitchell	2	contributed to other data analyses|designed the modelling methodology|developed the model code|wrote the initial draft of the manuscript	wrote the initial draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
6416473	30868739	Marcy Gelman	2	contributed to other data analyses	contributed to other data analyses	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6416473	30868739	Marie-Claude Boily	2	designed the modelling methodology|oversaw the study|wrote the initial draft of the manuscript|reviewed and edited the manuscript	designed the modelling methodology	Conceived and designed the experiments|Performed the experiments	Methodology	YES
6416473	30868739	Marie-Claude Boily	2	designed the modelling methodology|oversaw the study|wrote the initial draft of the manuscript|reviewed and edited the manuscript	oversaw the study	-	Supervision	YES
6416473	30868739	Marie-Claude Boily	2	designed the modelling methodology|oversaw the study|wrote the initial draft of the manuscript|reviewed and edited the manuscript	wrote the initial draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
6416473	30868739	Marie-Claude Boily	2	designed the modelling methodology|oversaw the study|wrote the initial draft of the manuscript|reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
1808432	17356698	DM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1808432	17356698	DM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1808432	17356698	DM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1808432	17356698	DM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1808432	17356698	JF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1808432	17356698	JF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1808432	17356698	JF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1808432	17356698	JF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1808432	17356698	MB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Participated in study design, conducted the molecular genotyping, and reviewed the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1808432	17356698	MB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Participated in study design, conducted the molecular genotyping, and reviewed the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
1808432	17356698	MB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Participated in study design, conducted the molecular genotyping, and reviewed the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1808432	17356698	MB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Participated in study design, conducted the molecular genotyping, and reviewed the manuscript	Participated in study design, conducted the molecular genotyping, and reviewed the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
1808432	17356698	MG	PLoS5	Conceived and designed the experiments|Analyzed the data|Conceived of the study, participated in its design and coordination, and helped to draft the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1808432	17356698	MG	PLoS5	Conceived and designed the experiments|Analyzed the data|Conceived of the study, participated in its design and coordination, and helped to draft the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
1808432	17356698	MG	PLoS5	Conceived and designed the experiments|Analyzed the data|Conceived of the study, participated in its design and coordination, and helped to draft the manuscript	Conceived of the study, participated in its design and coordination, and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
4411064	25915764	BL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411064	25915764	CQ	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411064	25915764	HF	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411064	25915764	JN	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411064	25915764	MT	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4411064	25915764	MX	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411064	25915764	MX	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411064	25915764	WL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411064	25915764	WZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411064	25915764	XJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411064	25915764	XJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411064	25915764	XJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411064	25915764	XP	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411064	25915764	XZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411064	25915764	YD	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411064	25915764	YD	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411064	25915764	YD	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
549535	15694003	DB	2	provided the bbsrc clones	provided the bbsrc clones	Contributed reagents/materials/analysis tools	Resources	YES
549535	15694003	FHCRC	2	clones, respectively	clones, respectively	-	-	NO
549535	15694003	JB	2	performed the analysis for clone selection	performed the analysis for clone selection	Performed the experiments	Investigation	YES
549535	15694003	JD	2	fabricated the microarrays|performed the analysis and validation of the microarray	fabricated the microarrays	Performed the experiments	Investigation	YES
549535	15694003	JD	2	fabricated the microarrays|performed the analysis and validation of the microarray	performed the analysis and validation of the microarray	Performed the experiments	Investigation|Validation	YES
549535	15694003	JT	2	performed the analysis for clone selection	performed the analysis for clone selection	Performed the experiments	Investigation	YES
549535	15694003	MA	2	generated the annotation file	generated the annotation file	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
549535	15694003	PN	2	performed the analysis and validation of the microarray	performed the analysis and validation of the microarray	Performed the experiments	Investigation|Validation	YES
549535	15694003	RB	2	fabricated the microarrays|performed the analysis and validation of the microarray	fabricated the microarrays	Performed the experiments	Investigation	YES
549535	15694003	RB	2	fabricated the microarrays|performed the analysis and validation of the microarray	performed the analysis and validation of the microarray	Performed the experiments	Investigation|Validation	YES
5662628	29123536	BR	2	made substantial contributions to conception, and critically revised the manuscript	made substantial contributions to conception, and critically revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5662628	29123536	BZ	2	made substantial contributions to conception, and critically revised the manuscript	made substantial contributions to conception, and critically revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5662628	29123536	JG	2	carried out the measurements, data analysis, and drafted the manuscript	carried out the measurements, data analysis, and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5662628	29123536	JZ	2	designed the experiment|made substantial contributions to conception, and critically revised the manuscript	designed the experiment	Conceived and designed the experiments	Methodology	YES
5662628	29123536	JZ	2	designed the experiment|made substantial contributions to conception, and critically revised the manuscript	made substantial contributions to conception, and critically revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5662628	29123536	PL	2	made substantial contributions to conception, and critically revised the manuscript	made substantial contributions to conception, and critically revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5662628	29123536	SD	2	made substantial contributions to conception, and critically revised the manuscript	made substantial contributions to conception, and critically revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
6416664	30869203	DJC	7	made substantial contributions to the design of the work; and interpretation of data for the work; and revised the work critically for important intellectual content; gave final approval of the version to be published; and agrees to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	made substantial contributions to the design of the work; and interpretation of data for the work; and revised the work critically for important intellectual content; gave final approval of the version to be published; and agrees to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Data curation|Formal analysis|Resources|Writing - Review & Editing	YES
6416664	30869203	EK	7	made substantial contributions to the design of the work; and to interpretation of data for the work; revised the work critically for important intellectual content; gave final approval of the version to be published; and agrees to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	made substantial contributions to the design of the work; and to interpretation of data for the work; revised the work critically for important intellectual content; gave final approval of the version to be published; and agrees to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Data curation|Formal analysis|Resources|Writing - Review & Editing	YES
6416664	30869203	GEH	7	made substantial contributions to the conception and design of the work, and to the analysis and interpretation of data for the work; drafted and revised the work for important intellectual content; gave final approval of the version to be published; and agrees to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	made substantial contributions to the conception and design of the work, and to the analysis and interpretation of data for the work; drafted and revised the work for important intellectual content; gave final approval of the version to be published; and agrees to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Data curation|Formal analysis|Resources|Writing - Original Draft|Writing - Review & Editing	YES
6416664	30869203	HLP	7	made substantial contributions to the conception and design of the work; and analysis and interpretation of data for the work; drafted the work and revised it critically for important intellectual content; gave final approval of the version to be published; and agrees to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	made substantial contributions to the conception and design of the work; and analysis and interpretation of data for the work; drafted the work and revised it critically for important intellectual content; gave final approval of the version to be published; and agrees to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Data curation|Formal analysis|Resources|Writing - Original Draft|Writing - Review & Editing	YES
6416664	30869203	JA	7	made substantial contributions to the design of the work; and interpretation of data for the work; revised the work critically for important intellectual content; gave final approval of the version to be published; and agrees to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	made substantial contributions to the design of the work; and interpretation of data for the work; revised the work critically for important intellectual content; gave final approval of the version to be published; and agrees to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Data curation|Formal analysis|Resources|Writing - Review & Editing	YES
6416664	30869203	KM	7	made substantial contributions to the analysis and interpretation of data for the work; drafted and revised the work for important intellectual content; gave final approval of the version to be published; and agrees to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	made substantial contributions to the analysis and interpretation of data for the work; drafted and revised the work for important intellectual content; gave final approval of the version to be published; and agrees to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Data curation|Formal analysis|Resources|Writing - Original Draft|Writing - Review & Editing	YES
6416664	30869203	MW	7	made substantial contributions to the analysis and interpretation of data for the work; drafted and revised the work for important intellectual content; gave final approval of the version to be published; and agrees to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	made substantial contributions to the analysis and interpretation of data for the work; drafted and revised the work for important intellectual content; gave final approval of the version to be published; and agrees to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Data curation|Formal analysis|Resources|Writing - Original Draft|Writing - Review & Editing	YES
6416664	30869203	NP	7	made substantial contributions to the interpretation of data for the work; revised the work critically for important intellectual content; gave final approval of the version to be published; and agrees to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	made substantial contributions to the interpretation of data for the work; revised the work critically for important intellectual content; gave final approval of the version to be published; and agrees to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Data curation|Formal analysis|Resources|Writing - Review & Editing	YES
6416664	30869203	NQO	7	made substantial contributions to the analysis and interpretation of data for the work; revised the work critically for important intellectual content; gave final approval of the version to be published; and agrees to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	made substantial contributions to the analysis and interpretation of data for the work; revised the work critically for important intellectual content; gave final approval of the version to be published; and agrees to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Data curation|Formal analysis|Resources|Writing - Review & Editing	YES
6416664	30869203	RJC	7	made substantial contributions to the conception and design of the work; and to the analysis and interpretation of data for the work; drafted and revised the work for important intellectual content; gave final approval of the version to be published; and agrees to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	made substantial contributions to the conception and design of the work; and to the analysis and interpretation of data for the work; drafted and revised the work for important intellectual content; gave final approval of the version to be published; and agrees to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Data curation|Formal analysis|Resources|Writing - Original Draft|Writing - Review & Editing	YES
6416664	30869203	SI	7	made substantial contributions to the conception and design of the work; and analysis and interpretation of data for the work; drafted the work and revised it critically for important intellectual content; gave final approval of the version to be published; and agrees to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	made substantial contributions to the conception and design of the work; and analysis and interpretation of data for the work; drafted the work and revised it critically for important intellectual content; gave final approval of the version to be published; and agrees to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Data curation|Formal analysis|Resources|Writing - Original Draft|Writing - Review & Editing	YES
6416664	30869203	TJ	7	made substantial contributions to the acquisition, analysis, and interpretation of data for the work; revised the work critically for important intellectual content; gave final approval of the version to be published; and agrees to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	made substantial contributions to the acquisition, analysis, and interpretation of data for the work; revised the work critically for important intellectual content; gave final approval of the version to be published; and agrees to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Data curation|Formal analysis|Investigation|Resources|Writing - Review & Editing	YES
5487713	28652490	Both authors	2	contributed equally to the writing of this paper	contributed equally to the writing of this paper	Wrote the paper	Writing - Original Draft	YES
4411066	25915403	CET	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411066	25915403	CET	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411066	25915403	CET	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411066	25915403	CET	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411066	25915403	JHT	PLoS5	Conceived and designed the experiments|Critical revision of the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411066	25915403	JHT	PLoS5	Conceived and designed the experiments|Critical revision of the manuscript	Critical revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4411066	25915403	PLS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411066	25915403	PLS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4411066	25915403	PLS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4411066	25915403	PLS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411066	25915403	SPO	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411066	25915403	SPO	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411066	25915403	SPO	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411066	25915403	SPO	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1808433	17356699	AI	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1808433	17356699	AR	PLoS5	Wrote the paper|Wrote the software	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1808433	17356699	AR	PLoS5	Wrote the paper|Wrote the software	Wrote the software	Contributed reagents/materials/analysis tools|Wrote the paper	Software|Writing - Original Draft	YES
1808433	17356699	DK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1808433	17356699	MN	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1808433	17356699	RK	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1808433	17356699	RK	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1808433	17356699	RK	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1808433	17356699	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1808433	17356699	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1808433	17356699	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1808433	17356699	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1808433	17356699	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
549560	15698474	AD	2	was at the origin of the project, participated in the design and evolution of the data schema, was the systematic tester and end-user and wrote the core of the article	was at the origin of the project, participated in the design and evolution of the data schema, was the systematic tester and end-user and wrote the core of the article	Conceived and designed the experiments|Wrote the paper	Data curation|Methodology|Writing - Original Draft	YES
549560	15698474	CC	2	implemented most of the databases into the core structure|the first leptolist database	implemented most of the databases into the core structure	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
549560	15698474	CC	2	implemented most of the databases into the core structure|the first leptolist database	the first leptolist database	Contributed reagents/materials/analysis tools	Software	YES
549560	15698474	FC	2	set up and administered the apache web server and mysql database	set up and administered the apache web server and mysql database	Performed the experiments|Contributed reagents/materials/analysis tools	Methodology|Software	YES
549560	15698474	IM	2	over the years designed most of the genolist data schema and user interface	over the years designed most of the genolist data schema and user interface	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Data curation|Software	YES
549560	15698474	VC	2	implemented most of the databases into the core structure	implemented most of the databases into the core structure	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
549560	15698474	YQ	2	implemented parts of the perl package	implemented parts of the perl package	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5662629	29123538	AD	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5662629	29123538	AK	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5662629	29123538	AS	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5662629	29123538	All the authors	2	revised the work critically for important intellectual content, approved the version to be published, and agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	revised the work critically for important intellectual content, approved the version to be published, and agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Wrote the paper	Writing - Review & Editing	YES
5662629	29123538	EB	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5662629	29123538	NM	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4411067	25915404	HA	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411067	25915404	JHK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411067	25915404	JP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411067	25915404	JP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411067	25915404	JP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411067	25915404	JP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411067	25915404	JP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411067	25915404	JSL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411067	25915404	MSL	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411067	25915404	MSL	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411067	25915404	SJY	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411067	25915404	WJK	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
6416665	30869202	All authors	2	reviewed and approved the final version	reviewed and approved the final version	-	-	NO
6416665	30869202	FM	2	conceptualized the analysis and the paper and also led the analyses|conceptualized the overall study and oversaw data collection	conceptualized the analysis and the paper and also led the analyses	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
6416665	30869202	FM	2	conceptualized the analysis and the paper and also led the analyses|conceptualized the overall study and oversaw data collection	conceptualized the overall study and oversaw data collection	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Supervision	YES
6416665	30869202	LC	2	conceptualized the overall study and oversaw data collection|contributed to the analyses and interpretation of the findings	conceptualized the overall study and oversaw data collection	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Supervision	YES
6416665	30869202	LC	2	conceptualized the overall study and oversaw data collection|contributed to the analyses and interpretation of the findings	contributed to the analyses and interpretation of the findings	Analyzed the data	Formal analysis	YES
6416665	30869202	MO	2	conceptualized the analysis and the paper and also led the analyses|conceptualized the overall study and oversaw data collection	conceptualized the analysis and the paper and also led the analyses	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
6416665	30869202	MO	2	conceptualized the analysis and the paper and also led the analyses|conceptualized the overall study and oversaw data collection	conceptualized the overall study and oversaw data collection	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Supervision	YES
4411068	25915938	Hee Jin Kim	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411068	25915938	Hee Jin Kim	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4411068	25915938	Hee Jin Kim	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411068	25915938	Hyun Jung Kim	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411068	25915938	Hyun Jung Kim	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411068	25915938	Hyun Jung Kim	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411068	25915938	Hyun Jung Kim	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411068	25915938	JSL	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4411068	25915938	SB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411068	25915938	SB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411068	25915938	SB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411068	25915938	SB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411068	25915938	SDL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411068	25915938	SWL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411068	25915938	SWL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411068	25915938	SWL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411068	25915938	SWL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411068	25915938	SWL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411068	25915938	YMO	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1810426	17375188	CH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1810426	17375188	CH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1810426	17375188	CH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1810426	17375188	CH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1810426	17375188	MM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1810426	17375188	MY	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1810426	17375188	PH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1810426	17375188	PH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1810426	17375188	PH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1810426	17375188	YG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1810426	17375188	YJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1810426	17375188	YJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1810426	17375188	YJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1810426	17375188	YJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5662645	29123541	AI	2	planned the research, design of experiments and handled the interpretation and preparation of the manuscript	planned the research, design of experiments and handled the interpretation and preparation of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
5662645	29123541	AK	2	planned the research, design of experiments and handled the interpretation and preparation of the manuscript	planned the research, design of experiments and handled the interpretation and preparation of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
5662645	29123541	BM	2	undertook the physiology, molecular biology, enzyme activity, and computational analyses|planned the research, design of experiments and handled the interpretation and preparation of the manuscript	undertook the physiology, molecular biology, enzyme activity, and computational analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5662645	29123541	BM	2	undertook the physiology, molecular biology, enzyme activity, and computational analyses|planned the research, design of experiments and handled the interpretation and preparation of the manuscript	planned the research, design of experiments and handled the interpretation and preparation of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
5662645	29123541	FE	2	took part in the physiology and molecular biology analyses	took part in the physiology and molecular biology analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5662645	29123541	TL	2	undertook the protein purification and part in the molecular biology|planned the research, design of experiments and handled the interpretation and preparation of the manuscript	undertook the protein purification and part in the molecular biology	Performed the experiments	Investigation	YES
5662645	29123541	TL	2	undertook the protein purification and part in the molecular biology|planned the research, design of experiments and handled the interpretation and preparation of the manuscript	planned the research, design of experiments and handled the interpretation and preparation of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
5487716	28652493	RSK	2	contributed their practical knowledge and commercial view on the requirements for a novel atom interferometer	contributed their practical knowledge and commercial view on the requirements for a novel atom interferometer	-	-	NO
5496148	28673242	All authors	2	contributed to the research and read and approved the final manuscript	contributed to the research and read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5496148	28673242	GHX	2	designed the experiment|performed experiments and supervised data analysis	designed the experiment	Conceived and designed the experiments	Methodology	YES
5496148	28673242	GHX	2	designed the experiment|performed experiments and supervised data analysis	performed experiments and supervised data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Supervision	YES
5496148	28673242	HX	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5496148	28673242	JNY	2	designed the experiment|revised the manuscript	designed the experiment	Conceived and designed the experiments	Methodology	YES
5496148	28673242	JNY	2	designed the experiment|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5496148	28673242	LMW	2	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5496148	28673242	PH	2	performed experiments and supervised data analysis|analyzed data	performed experiments and supervised data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Supervision	YES
5496148	28673242	PH	2	performed experiments and supervised data analysis|analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5496148	28673242	PZ	2	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5496148	28673242	XSW	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5496148	28673242	YZZ	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6416666	30869200	A.A.A.	PLoS52	designed the qualitative substudy	designed the qualitative substudy	Conceived and designed the experiments	Methodology	YES
6416666	30869200	B.E.M.	PLoS52	analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
6416666	30869200	C.R.	PLoS52	analysed the data|wrote the manuscript with all other authors contributing on review and revisions	analysed the data	Analyzed the data	Formal analysis	YES
6416666	30869200	C.R.	PLoS52	analysed the data|wrote the manuscript with all other authors contributing on review and revisions	wrote the manuscript with all other authors contributing on review and revisions	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6416666	30869200	J.S.	PLoS52	analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
6416666	30869200	J.W.	PLoS52	analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
6416666	30869200	K.R.A.	PLoS52	designed the qualitative substudy|as protocol team members|analysed the data|wrote the manuscript with all other authors contributing on review and revisions	designed the qualitative substudy	Conceived and designed the experiments	Methodology	YES
6416666	30869200	K.R.A.	PLoS52	designed the qualitative substudy|as protocol team members|analysed the data|wrote the manuscript with all other authors contributing on review and revisions	as protocol team members	Conceived and designed the experiments	Methodology	YES
6416666	30869200	K.R.A.	PLoS52	designed the qualitative substudy|as protocol team members|analysed the data|wrote the manuscript with all other authors contributing on review and revisions	analysed the data	Analyzed the data	Formal analysis	YES
6416666	30869200	K.R.A.	PLoS52	designed the qualitative substudy|as protocol team members|analysed the data|wrote the manuscript with all other authors contributing on review and revisions	wrote the manuscript with all other authors contributing on review and revisions	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6416666	30869200	M.M.	PLoS52	as protocol team members	as protocol team members	Conceived and designed the experiments	Methodology	YES
6416666	30869200	M.R.C.	PLoS52	analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
6416666	30869200	N.D.T.	PLoS52	implementing the interviews	implementing the interviews	Performed the experiments	Investigation	YES
6416666	30869200	R.J.L.	PLoS52	as protocol team members	as protocol team members	Conceived and designed the experiments	Methodology	YES
6416666	30869200	S.H.	PLoS52	designed the qualitative substudy|as protocol team members	designed the qualitative substudy	Conceived and designed the experiments	Methodology	YES
6416666	30869200	S.H.	PLoS52	designed the qualitative substudy|as protocol team members	as protocol team members	Conceived and designed the experiments	Methodology	YES
1810427	17375189	CN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1810427	17375189	CN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1810427	17375189	CN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1810427	17375189	CN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1810427	17375189	CN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1810427	17375189	HS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1810427	17375189	HS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1810427	17375189	HS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5540841	28739966	A.J.P.W.	2	collected and processed x-ray crystallography data	collected and processed x-ray crystallography data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5540841	28739966	D.-H.H.	2	contributed to the experimental data and characterization studies	contributed to the experimental data and characterization studies	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5540841	28739966	J.S.S.	2	carried out the majority of the experiments and characterization, interpreting the results and writing the manuscript	carried out the majority of the experiments and characterization, interpreting the results and writing the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5540841	28739966	R.C.T.-R.	2	carried out the majority of the experiments and characterization, interpreting the results and writing the manuscript	carried out the majority of the experiments and characterization, interpreting the results and writing the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5540841	28739966	R.T.C.	2	carried out the majority of the experiments and characterization, interpreting the results and writing the manuscript	carried out the majority of the experiments and characterization, interpreting the results and writing the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4411069	25915766	SCC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411069	25915766	SCC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411069	25915766	SCC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411069	25915766	TR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411069	25915766	TR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411069	25915766	TR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411069	25915766	TR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5662649	29123540	G-CZ	2	participated in the data analysis	participated in the data analysis	Analyzed the data	Formal analysis	YES
5662649	29123540	J-YX	2	participated in the data analysis|modified the manuscript	participated in the data analysis	Analyzed the data	Formal analysis	YES
5662649	29123540	J-YX	2	participated in the data analysis|modified the manuscript	modified the manuscript	Wrote the paper	Writing - Review & Editing	YES
5662649	29123540	L-WL	2	participated in the data analysis	participated in the data analysis	Analyzed the data	Formal analysis	YES
5662649	29123540	MC	2	participated in the data analysis	participated in the data analysis	Analyzed the data	Formal analysis	YES
5662649	29123540	X-QS	2	participated in the data analysis	participated in the data analysis	Analyzed the data	Formal analysis	YES
5662649	29123540	Y-MZ	2	conceived and designed the project|obtained and analyzed the data|drafted the manuscript	conceived and designed the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5662649	29123540	Y-MZ	2	conceived and designed the project|obtained and analyzed the data|drafted the manuscript	obtained and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5662649	29123540	Y-MZ	2	conceived and designed the project|obtained and analyzed the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5662649	29123540	Y-YH	2	conceived and designed the project|modified the manuscript	conceived and designed the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5662649	29123540	Y-YH	2	conceived and designed the project|modified the manuscript	modified the manuscript	Wrote the paper	Writing - Review & Editing	YES
5662649	29123540	Z-QS	2	conceived and designed the project|obtained and analyzed the data|modified the manuscript	conceived and designed the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5662649	29123540	Z-QS	2	conceived and designed the project|obtained and analyzed the data|modified the manuscript	obtained and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5662649	29123540	Z-QS	2	conceived and designed the project|obtained and analyzed the data|modified the manuscript	modified the manuscript	Wrote the paper	Writing - Review & Editing	YES
5496183	28673249	DL	2	conducted validation of experiments|contributed powerful analytical tools	conducted validation of experiments	Performed the experiments	Investigation|Validation	YES
5496183	28673249	DL	2	conducted validation of experiments|contributed powerful analytical tools	contributed powerful analytical tools	Contributed reagents/materials/analysis tools	Resources	YES
5496183	28673249	HJ	2	conducted validation of experiments	conducted validation of experiments	Performed the experiments	Investigation|Validation	YES
5496183	28673249	LL	2	conceived and designed the research	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5496183	28673249	LX	2	conceived and designed the research	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5496183	28673249	MT	2	conducted validation of experiments	conducted validation of experiments	Performed the experiments	Investigation|Validation	YES
5496183	28673249	WZ	2	contributed powerful analytical tools	contributed powerful analytical tools	Contributed reagents/materials/analysis tools	Resources	YES
5496183	28673249	XL	2	performed the data analysis and wrote the manuscript	performed the data analysis and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5496183	28673249	XZ	2	helped with the revise of manuscript	helped with the revise of manuscript	Wrote the paper	Writing - Review & Editing	YES
5496183	28673249	YW	2	contributed powerful analytical tools	contributed powerful analytical tools	Contributed reagents/materials/analysis tools	Resources	YES
5496183	28673249	YZ	2	helped with the revise of manuscript	helped with the revise of manuscript	Wrote the paper	Writing - Review & Editing	YES
6426069	29479861	AG	2	developed the protocol including literature search and study design|were involved in data analysis	developed the protocol including literature search and study design	Conceived and designed the experiments	Formal analysis|Methodology	YES
6426069	29479861	AG	2	developed the protocol including literature search and study design|were involved in data analysis	were involved in data analysis	Analyzed the data	Formal analysis	YES
6426069	29479861	All authors	2	contributed to editing the final report, were involved in the development of the primary manuscript, interpretation of data, and read and approved the final version	contributed to editing the final report, were involved in the development of the primary manuscript, interpretation of data, and read and approved the final version	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft|Writing - Review & Editing	YES
6426069	29479861	BU	2	developed the protocol including literature search and study design|were involved in data collection|were involved in data analysis	developed the protocol including literature search and study design	Conceived and designed the experiments	Formal analysis|Methodology	YES
6426069	29479861	BU	2	developed the protocol including literature search and study design|were involved in data collection|were involved in data analysis	were involved in data collection	Performed the experiments	Investigation	YES
6426069	29479861	BU	2	developed the protocol including literature search and study design|were involved in data collection|were involved in data analysis	were involved in data analysis	Analyzed the data	Formal analysis	YES
6426069	29479861	CK	2	developed the protocol including literature search and study design|were involved in data analysis	developed the protocol including literature search and study design	Conceived and designed the experiments	Formal analysis|Methodology	YES
6426069	29479861	CK	2	developed the protocol including literature search and study design|were involved in data analysis	were involved in data analysis	Analyzed the data	Formal analysis	YES
6426069	29479861	CO	2	were involved in data collection	were involved in data collection	Performed the experiments	Investigation	YES
6426069	29479861	DN	2	developed the protocol including literature search and study design	developed the protocol including literature search and study design	Conceived and designed the experiments	Formal analysis|Methodology	YES
6426069	29479861	EO	2	developed the protocol including literature search and study design	developed the protocol including literature search and study design	Conceived and designed the experiments	Formal analysis|Methodology	YES
6426069	29479861	IS	2	were involved in data collection|were involved in data analysis	were involved in data collection	Performed the experiments	Investigation	YES
6426069	29479861	IS	2	were involved in data collection|were involved in data analysis	were involved in data analysis	Analyzed the data	Formal analysis	YES
6426069	29479861	JN	2	developed the protocol including literature search and study design	developed the protocol including literature search and study design	Conceived and designed the experiments	Formal analysis|Methodology	YES
6426069	29479861	LV	2	developed the protocol including literature search and study design|were involved in data analysis	developed the protocol including literature search and study design	Conceived and designed the experiments	Formal analysis|Methodology	YES
6426069	29479861	LV	2	developed the protocol including literature search and study design|were involved in data analysis	were involved in data analysis	Analyzed the data	Formal analysis	YES
6426069	29479861	NB	2	developed the protocol including literature search and study design	developed the protocol including literature search and study design	Conceived and designed the experiments	Formal analysis|Methodology	YES
6426069	29479861	POO	2	developed the protocol including literature search and study design	developed the protocol including literature search and study design	Conceived and designed the experiments	Formal analysis|Methodology	YES
6426069	29479861	TP	2	were involved in data analysis	were involved in data analysis	Analyzed the data	Formal analysis	YES
6426069	29479861	VB	2	were involved in data collection	were involved in data collection	Performed the experiments	Investigation	YES
6426069	29479861	YF	2	were involved in data analysis	were involved in data analysis	Analyzed the data	Formal analysis	YES
1810428	17375190	SJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1810428	17375190	SJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1810428	17375190	SJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1810428	17375190	TH	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1810428	17375190	TH	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1810428	17375190	XD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1810428	17375190	XD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1810428	17375190	XD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1810428	17375190	XD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411070	25915770	CR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411070	25915770	CR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411070	25915770	CR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411070	25915770	CR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411070	25915770	CR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4564601	26413524	Joseph W. Musana	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
4564601	26413524	Kiran Shaikh	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
4564601	26413524	Pauline Samia	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
4564601	26413524	Salima Sulaiman	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
5540842	28739967	L.Y.P.L.	2	conceived and designed the study in addition to manuscript preparation	conceived and designed the study in addition to manuscript preparation	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
5540842	28739967	N.S.	2	prepared and characterized the dihydropyridine reagents	prepared and characterized the dihydropyridine reagents	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5540842	28739967	R.L.M.	2	conceived and designed the study in addition to manuscript preparation	conceived and designed the study in addition to manuscript preparation	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
5496224	28673247	AI	2	conceived the research	conceived the research	Conceived and designed the experiments	Conceptualization	YES
5496224	28673247	All	2	authors reviewed and approved the submitted manuscript	authors reviewed and approved the submitted manuscript	Wrote the paper	Writing - Review & Editing	YES
5496224	28673247	LQH	2	conceived the research|authors reviewed and approved the submitted manuscript	conceived the research	Conceived and designed the experiments	Conceptualization	YES
5496224	28673247	LQH	2	conceived the research|authors reviewed and approved the submitted manuscript	authors reviewed and approved the submitted manuscript	Wrote the paper	Writing - Review & Editing	YES
5496224	28673247	OAR	2	conceived the research	conceived the research	Conceived and designed the experiments	Conceptualization	YES
5496224	28673247	ZM	2	conceived the research	conceived the research	Conceived and designed the experiments	Conceptualization	YES
5559414	28784709	A.J.W.	2	wrote the initial draft and all authors contributed to its revision	wrote the initial draft and all authors contributed to its revision	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5559414	28784709	B.J.W.M.	2	performed the final runs	performed the final runs	Performed the experiments	Investigation	YES
5559414	28784709	T.M.L.	2	formulated the model and all authors developed it	formulated the model and all authors developed it	Conceived and designed the experiments|Performed the experiments	Conceptualization|Methodology	YES
6428502	30897303	All authors	PLoS52	have read and approved the final manuscript	have read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6428502	30897303	CDD	PLoS52	performed the research	performed the research	Performed the experiments	Investigation	YES
6428502	30897303	DJC	PLoS52	designed the research study|performed the research	designed the research study	Conceived and designed the experiments	Methodology	YES
6428502	30897303	DJC	PLoS52	designed the research study|performed the research	performed the research	Performed the experiments	Investigation	YES
6428502	30897303	HD	PLoS52	analysed the data|wrote the paper	analysed the data	Analyzed the data	Formal analysis	YES
6428502	30897303	HD	PLoS52	analysed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6428502	30897303	HL	PLoS52	designed the research study	designed the research study	Conceived and designed the experiments	Methodology	YES
6428502	30897303	JHE	PLoS52	designed the research study	designed the research study	Conceived and designed the experiments	Methodology	YES
6428502	30897303	JHM	PLoS52	designed the research study	designed the research study	Conceived and designed the experiments	Methodology	YES
6428502	30897303	LN	PLoS52	analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
6428502	30897303	TDN	PLoS52	performed the research	performed the research	Performed the experiments	Investigation	YES
6428502	30897303	TMP	PLoS52	performed the research	performed the research	Performed the experiments	Investigation	YES
6428502	30897303	TP	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6428502	30897303	TTP	PLoS52	designed the research study|performed the research	designed the research study	Conceived and designed the experiments	Methodology	YES
6428502	30897303	TTP	PLoS52	designed the research study|performed the research	performed the research	Performed the experiments	Investigation	YES
3293722	22280528	All authors	2	as a research team, carried out the microbiological experiments, bioassay tests and protein estimation, protein profile analysis, dna extraction matching and submission the sequencing data in the database of gene bank	as a research team, carried out the microbiological experiments, bioassay tests and protein estimation, protein profile analysis, dna extraction matching and submission the sequencing data in the database of gene bank	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Software	YES
3293722	22280528	FMR	2	suggested the research problem and outlined research plan, interpreted the data, prepared the manuscript and have given final approval of the version for publication|as a research team, carried out the microbiological experiments, bioassay tests and protein estimation, protein profile analysis, dna extraction matching and submission the sequencing data in the database of gene bank	suggested the research problem and outlined research plan, interpreted the data, prepared the manuscript and have given final approval of the version for publication	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3293722	22280528	FMR	2	suggested the research problem and outlined research plan, interpreted the data, prepared the manuscript and have given final approval of the version for publication|as a research team, carried out the microbiological experiments, bioassay tests and protein estimation, protein profile analysis, dna extraction matching and submission the sequencing data in the database of gene bank	as a research team, carried out the microbiological experiments, bioassay tests and protein estimation, protein profile analysis, dna extraction matching and submission the sequencing data in the database of gene bank	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Software	YES
3293722	22280528	HMF	2	as a research team, carried out the microbiological experiments, bioassay tests and protein estimation, protein profile analysis, dna extraction matching and submission the sequencing data in the database of gene bank|carried out statistical analysis and figured data	as a research team, carried out the microbiological experiments, bioassay tests and protein estimation, protein profile analysis, dna extraction matching and submission the sequencing data in the database of gene bank	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Software	YES
3293722	22280528	HMF	2	as a research team, carried out the microbiological experiments, bioassay tests and protein estimation, protein profile analysis, dna extraction matching and submission the sequencing data in the database of gene bank|carried out statistical analysis and figured data	carried out statistical analysis and figured data	Analyzed the data	Formal analysis|Visualization	YES
3293722	22280528	MN	2	as a research team, carried out the microbiological experiments, bioassay tests and protein estimation, protein profile analysis, dna extraction matching and submission the sequencing data in the database of gene bank	as a research team, carried out the microbiological experiments, bioassay tests and protein estimation, protein profile analysis, dna extraction matching and submission the sequencing data in the database of gene bank	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Software	YES
3293722	22280528	WDS	2	as a research team, carried out the microbiological experiments, bioassay tests and protein estimation, protein profile analysis, dna extraction matching and submission the sequencing data in the database of gene bank	as a research team, carried out the microbiological experiments, bioassay tests and protein estimation, protein profile analysis, dna extraction matching and submission the sequencing data in the database of gene bank	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Software	YES
5662652	29123535	MSB	2	carried out experiment and collected the data	carried out experiment and collected the data	Performed the experiments	Investigation	YES
5662652	29123535	RKB	2	did data analysis and wrote manuscript	did data analysis and wrote manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5662652	29123535	SKM	2	corrected the manuscript	corrected the manuscript	Wrote the paper	Writing - Review & Editing	YES
5662652	29123535	SN	2	designed the experiment|corrected the manuscript	designed the experiment	Conceived and designed the experiments	Methodology	YES
5662652	29123535	SN	2	designed the experiment|corrected the manuscript	corrected the manuscript	Wrote the paper	Writing - Review & Editing	YES
5662652	29123535	SRV	2	corrected the manuscript	corrected the manuscript	Wrote the paper	Writing - Review & Editing	YES
5662652	29123535	VGNTV	2	carried out experiment and collected the data	carried out experiment and collected the data	Performed the experiments	Investigation	YES
5662652	29123535	VVP	2	designed the experiment|carried out experiment and collected the data	designed the experiment	Conceived and designed the experiments	Methodology	YES
5662652	29123535	VVP	2	designed the experiment|carried out experiment and collected the data	carried out experiment and collected the data	Performed the experiments	Investigation	YES
5559419	28784714	A.C.N.G.	2	developed the fundamental ideas of and wrote the manuscript	developed the fundamental ideas of and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5559419	28784714	A.J.S.M.	2	conducted the analyses in figures 3 - 6 , respectively	conducted the analyses in figures 3 - 6 , respectively	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
5559419	28784714	All authors	2	contributed to the discussion of results	contributed to the discussion of results	-	-	NO
5559419	28784714	G.A.M.	2	conducted the analyses in figures 3 - 6 , respectively	conducted the analyses in figures 3 - 6 , respectively	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
5559419	28784714	P.J.B.	2	conducted the analyses in figures 3 - 6 , respectively	conducted the analyses in figures 3 - 6 , respectively	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
4411071	25915862	GUL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411071	25915862	HZW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411071	25915862	HZW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411071	25915862	JQS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411071	25915862	JQS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411071	25915862	JQS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411071	25915862	JQS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411071	25915862	NL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411071	25915862	NL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411071	25915862	NL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411071	25915862	NL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411071	25915862	WP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411071	25915862	XFW	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1810429	17375191	GE	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1810429	17375191	GE	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1810429	17375191	GE	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1810429	17375191	JD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1810429	17375191	JD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1810429	17375191	JD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1810429	17375191	JD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6432101	30907515	CJ	2	substantially provided intellectual input to the manuscript	substantially provided intellectual input to the manuscript	-	-	NO
6432101	30907515	CM	2	collected the data and informed the design of data collection methods	collected the data and informed the design of data collection methods	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6432101	30907515	CW	2	collected the data and informed the design of data collection methods	collected the data and informed the design of data collection methods	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6432101	30907515	ELC	2	formulated the research study and design|substantially provided intellectual input to the manuscript	formulated the research study and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6432101	30907515	ELC	2	formulated the research study and design|substantially provided intellectual input to the manuscript	substantially provided intellectual input to the manuscript	-	-	NO
6432101	30907515	ELS	2	formulated the research study and design|wrote the first draft of the manuscript	formulated the research study and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6432101	30907515	ELS	2	formulated the research study and design|wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
6432101	30907515	FMC	2	formulated the research study and design|substantially provided intellectual input to the manuscript	formulated the research study and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6432101	30907515	FMC	2	formulated the research study and design|substantially provided intellectual input to the manuscript	substantially provided intellectual input to the manuscript	-	-	NO
6432101	30907515	FTP	2	formulated the research study and design|analysed the data or contributed to the analysis|substantially provided intellectual input to the manuscript	formulated the research study and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6432101	30907515	FTP	2	formulated the research study and design|analysed the data or contributed to the analysis|substantially provided intellectual input to the manuscript	analysed the data or contributed to the analysis	Analyzed the data	Formal analysis	YES
6432101	30907515	FTP	2	formulated the research study and design|analysed the data or contributed to the analysis|substantially provided intellectual input to the manuscript	substantially provided intellectual input to the manuscript	-	-	NO
6432101	30907515	GM	2	analysed the data or contributed to the analysis	analysed the data or contributed to the analysis	Analyzed the data	Formal analysis	YES
6432101	30907515	JJO	2	substantially provided intellectual input to the manuscript	substantially provided intellectual input to the manuscript	-	-	NO
6432101	30907515	JRH	2	substantially provided intellectual input to the manuscript	substantially provided intellectual input to the manuscript	-	-	NO
6432101	30907515	KH	2	formulated the research study and design|substantially provided intellectual input to the manuscript	formulated the research study and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6432101	30907515	KH	2	formulated the research study and design|substantially provided intellectual input to the manuscript	substantially provided intellectual input to the manuscript	-	-	NO
6432101	30907515	MDE	2	formulated the research study and design|analysed the data or contributed to the analysis|wrote the first draft of the manuscript	formulated the research study and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6432101	30907515	MDE	2	formulated the research study and design|analysed the data or contributed to the analysis|wrote the first draft of the manuscript	analysed the data or contributed to the analysis	Analyzed the data	Formal analysis	YES
6432101	30907515	MDE	2	formulated the research study and design|analysed the data or contributed to the analysis|wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
6432101	30907515	MT	2	formulated the research study and design|formulated the research study and design|collected the data and informed the design of data collection methods	formulated the research study and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6432101	30907515	MT	2	formulated the research study and design|formulated the research study and design|collected the data and informed the design of data collection methods	formulated the research study and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6432101	30907515	MT	2	formulated the research study and design|formulated the research study and design|collected the data and informed the design of data collection methods	collected the data and informed the design of data collection methods	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6432101	30907515	NR	2	collected the data and informed the design of data collection methods	collected the data and informed the design of data collection methods	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6432101	30907515	PI	2	analysed the data or contributed to the analysis	analysed the data or contributed to the analysis	Analyzed the data	Formal analysis	YES
5496257	28676104	All authors	2	contributed experimental design oversight|reviewed and approved the final version of the manuscript	contributed experimental design oversight	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Supervision	YES
5496257	28676104	All authors	2	contributed experimental design oversight|reviewed and approved the final version of the manuscript	reviewed and approved the final version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5496257	28676104	CJF	2	aided with experimental design and supervised the whole project|provided spinal cord and brainstem data	aided with experimental design and supervised the whole project	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Supervision	YES
5496257	28676104	CJF	2	aided with experimental design and supervised the whole project|provided spinal cord and brainstem data	provided spinal cord and brainstem data	Contributed reagents/materials/analysis tools	Resources	YES
5496257	28676104	EYS	2	produced the lncrna annotation pipeline and did the data analysis|provided the cerebellar rna seq data	produced the lncrna annotation pipeline and did the data analysis	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5496257	28676104	EYS	2	produced the lncrna annotation pipeline and did the data analysis|provided the cerebellar rna seq data	provided the cerebellar rna seq data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5496257	28676104	JDM	2	aided with experimental design and supervised the whole project|provided the cerebellar rna seq data	aided with experimental design and supervised the whole project	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Supervision	YES
5496257	28676104	JDM	2	aided with experimental design and supervised the whole project|provided the cerebellar rna seq data	provided the cerebellar rna seq data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5496257	28676104	MCP	2	provided the cerebellar rna seq data	provided the cerebellar rna seq data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5496257	28676104	MJM	2	provided retina and skin data	provided retina and skin data	Contributed reagents/materials/analysis tools	Resources	YES
5496257	28676104	PJR	2	provided both embryonic tissue data	provided both embryonic tissue data	Contributed reagents/materials/analysis tools	Resources	YES
5496257	28676104	RRB	2	provided retina and skin data	provided retina and skin data	Contributed reagents/materials/analysis tools	Resources	YES
5496257	28676104	SJV	2	provided muscle data	provided muscle data	Contributed reagents/materials/analysis tools	Resources	YES
5496257	28676104	TAM	2	produced the lncrna annotation pipeline and did the data analysis	produced the lncrna annotation pipeline and did the data analysis	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
4411072	25915509	AT	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4411072	25915509	BK	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4411072	25915509	BK	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4411072	25915509	CS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411072	25915509	CS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411072	25915509	CS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411072	25915509	CS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411072	25915509	ER	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4411072	25915509	ER	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4411072	25915509	FL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4411072	25915509	FL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411072	25915509	JW	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411072	25915509	JW	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411072	25915509	JW	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411072	25915509	PR	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411072	25915509	PS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411072	25915509	PS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411072	25915509	PS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411072	25915509	PS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411072	25915509	RP	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411072	25915509	US	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411072	25915509	US	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411072	25915509	US	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5662881	29123534	AB	7	collated information for the tools reviewed	collated information for the tools reviewed	-	-	NO
5662881	29123534	LT	7	20% contribution to writing review and coordinated work for review	20% contribution to writing review and coordinated work for review	Wrote the paper	Project administration|Writing - Review & Editing	YES
5662881	29123534	SJ	7	formulated the review and wrote 70% of the review	formulated the review and wrote 70% of the review	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5662881	29123534	SM	7	10% contribution to writing review	10% contribution to writing review	Wrote the paper	Writing - Review & Editing	YES
1810430	17375192	CK	PLoS5	Wrote the paper|Directed the investigations	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1810430	17375192	CK	PLoS5	Wrote the paper|Directed the investigations	Directed the investigations	Performed the experiments	Investigation|Supervision	YES
1810430	17375192	CR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1810430	17375192	CR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1810430	17375192	CR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
6432102	30907496	AM	2	were the principal data collectors and contributed to the first draft	were the principal data collectors and contributed to the first draft	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6432102	30907496	CJ	2	provided a thorough review of the drafts and contributed to the second draft	provided a thorough review of the drafts and contributed to the second draft	Wrote the paper	Writing - Original Draft	YES
6432102	30907496	ELC	2	provided a thorough review of the drafts and contributed to the second draft	provided a thorough review of the drafts and contributed to the second draft	Wrote the paper	Writing - Original Draft	YES
6432102	30907496	ES	2	also contributed to first draft and reviewed subsequent iterations	also contributed to first draft and reviewed subsequent iterations	Wrote the paper	Writing - Original Draft	YES
6432102	30907496	HA	2	provided a thorough review of the drafts and contributed to the second draft	provided a thorough review of the drafts and contributed to the second draft	Wrote the paper	Writing - Original Draft	YES
6432102	30907496	KH	2	provided a thorough review of the drafts and contributed to the second draft	provided a thorough review of the drafts and contributed to the second draft	Wrote the paper	Writing - Original Draft	YES
6432102	30907496	LK	2	were the principal data collectors and contributed to the first draft	were the principal data collectors and contributed to the first draft	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6432102	30907496	LN	2	also contributed to first draft and reviewed subsequent iterations	also contributed to first draft and reviewed subsequent iterations	Wrote the paper	Writing - Original Draft	YES
6432102	30907496	MK	2	wrote first draft and led the entire writing process	wrote first draft and led the entire writing process	Wrote the paper	Writing - Original Draft	YES
6432102	30907496	MS	2	wrote first draft and led the entire writing process	wrote first draft and led the entire writing process	Wrote the paper	Writing - Original Draft	YES
6432102	30907496	PI	2	also contributed to first draft and reviewed subsequent iterations	also contributed to first draft and reviewed subsequent iterations	Wrote the paper	Writing - Original Draft	YES
6432102	30907496	RD	2	also contributed to first draft and reviewed subsequent iterations	also contributed to first draft and reviewed subsequent iterations	Wrote the paper	Writing - Original Draft	YES
5580445	28827423	A.H.	2	carried out the remainder of the experiments and data processing, apparatus calibration, specimen fabrication and microstructural study	carried out the remainder of the experiments and data processing, apparatus calibration, specimen fabrication and microstructural study	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5580445	28827423	Both authors	2	give final approval for publication	give final approval for publication	-	-	NO
5580445	28827423	E.R.	2	conceived of the study, carried out the greater fraction of the experiments and data processing, the interpretation of results and the drafting and revising of the paper	conceived of the study, carried out the greater fraction of the experiments and data processing, the interpretation of results and the drafting and revising of the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Data curation|Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5496318	28673244	DMU	2	designed the study, performed the analysis, and interpreted the results|wrote the manuscript	designed the study, performed the analysis, and interpreted the results	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5496318	28673244	DMU	2	designed the study, performed the analysis, and interpreted the results|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5496318	28673244	KK	2	performed the analysis	performed the analysis	Performed the experiments	Investigation	YES
5496318	28673244	KL	2	performed the analysis	performed the analysis	Performed the experiments	Investigation	YES
5496318	28673244	LL	2	conceived the study|designed the study, performed the analysis, and interpreted the results|wrote the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5496318	28673244	LL	2	conceived the study|designed the study, performed the analysis, and interpreted the results|wrote the manuscript	designed the study, performed the analysis, and interpreted the results	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5496318	28673244	LL	2	conceived the study|designed the study, performed the analysis, and interpreted the results|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5496318	28673244	NC	2	performed the analysis	performed the analysis	Performed the experiments	Investigation	YES
5496318	28673244	YL	2	designed the study, performed the analysis, and interpreted the results|wrote the manuscript	designed the study, performed the analysis, and interpreted the results	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5496318	28673244	YL	2	designed the study, performed the analysis, and interpreted the results|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4411073	25915950	HYH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411073	25915950	HYH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411073	25915950	HYH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411073	25915950	LLA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411073	25915950	LLA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411073	25915950	LLA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411073	25915950	LLA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411073	25915950	LLA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411073	25915950	NL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411073	25915950	NL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411073	25915950	NL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411073	25915950	NL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411073	25915950	NL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4564607	26448949	Hidetoshi Nagata	2	did clinical work for the cases and collected the data for this paper	did clinical work for the cases and collected the data for this paper	Performed the experiments	Investigation	YES
4564607	26448949	Hirokazu Tomishige	2	did clinical work for the cases and collected the data for this paper	did clinical work for the cases and collected the data for this paper	Performed the experiments	Investigation	YES
4564607	26448949	Jin Kawase	2	did clinical work for the cases and collected the data for this paper	did clinical work for the cases and collected the data for this paper	Performed the experiments	Investigation	YES
4564607	26448949	Masashi Isetani	2	did clinical work for the cases and collected the data for this paper	did clinical work for the cases and collected the data for this paper	Performed the experiments	Investigation	YES
4564607	26448949	Norihiko Kawabe	2	did clinical work for the cases and collected the data for this paper	did clinical work for the cases and collected the data for this paper	Performed the experiments	Investigation	YES
4564607	26448949	Satoshi Arakawa	2	did clinical work for the cases and collected the data for this paper	did clinical work for the cases and collected the data for this paper	Performed the experiments	Investigation	YES
4564607	26448949	Zenichi Morise	2	planned and performed the reported procedures and wrote this paper	planned and performed the reported procedures and wrote this paper	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
6432103	30907517	A.L.R.	2	made substantial contributions to formalize the concept of the commentary and development of the draft	made substantial contributions to formalize the concept of the commentary and development of the draft	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
6432103	30907517	All authors	2	have given final approval of the version to be published	have given final approval of the version to be published	-	-	NO
6432103	30907517	C.J.	2	have been involved in reviewing the commentary and providing valuable input	have been involved in reviewing the commentary and providing valuable input	-	-	NO
6432103	30907517	E.C.	2	have been involved in reviewing the commentary and providing valuable input	have been involved in reviewing the commentary and providing valuable input	-	-	NO
6432103	30907517	H.I.	2	made substantial contributions to formalize the concept of the commentary and development of the draft	made substantial contributions to formalize the concept of the commentary and development of the draft	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
6432103	30907517	K.H.	2	have been involved in reviewing the commentary and providing valuable input	have been involved in reviewing the commentary and providing valuable input	-	-	NO
6432103	30907517	O.M.	2	made substantial contributions to formalize the concept of the commentary and development of the draft	made substantial contributions to formalize the concept of the commentary and development of the draft	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
6432103	30907517	R.B.	2	have been involved in reviewing the commentary and providing valuable input	have been involved in reviewing the commentary and providing valuable input	-	-	NO
6432103	30907517	R.L.	2	contributed to the concept and evolution of the commentary	contributed to the concept and evolution of the commentary	Conceived and designed the experiments	Conceptualization	YES
1810431	17372627	ER	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1810431	17372627	ER	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1810431	17372627	ER	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1810431	17372627	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1810431	17372627	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1810431	17372627	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1810431	17372627	MG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1810431	17372627	MG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1810431	17372627	MG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1810431	17372627	VV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1810431	17372627	VV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1810431	17372627	VV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5496330	28673258	BM	2	analyzed ngs data	analyzed ngs data	Analyzed the data	Formal analysis	YES
5496330	28673258	GS	2	assisted in generating primers, performing qpcr experiments	assisted in generating primers, performing qpcr experiments	Performed the experiments	Investigation	YES
5496330	28673258	JRH	2	provided directions and critiques	provided directions and critiques	-	-	NO
5496330	28673258	NSR	2	comprehended the idea and designed the experiments	comprehended the idea and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5597724	28871050	J.L.	5	managed Phase 2 and R	managed Phase 2 and R	-	-	NO
5597724	28871050	K.F.	5	created the hacms program and managed Phase 1	created the hacms program and managed Phase 1	-	-	NO
4411074	25915906	JH	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411074	25915906	JH	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411074	25915906	JH	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411074	25915906	KB	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411074	25915906	KB	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411074	25915906	KL	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411074	25915906	KL	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411074	25915906	KL	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411074	25915906	LJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411074	25915906	LJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411074	25915906	LJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411074	25915906	NL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411074	25915906	NL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411074	25915906	NL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411074	25915906	NL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411074	25915906	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411074	25915906	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411074	25915906	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5662899	29123532	AS	2	collected all the literature and compiled the information|wrote the article	collected all the literature and compiled the information	Performed the experiments	Formal analysis|Investigation	YES
5662899	29123532	AS	2	collected all the literature and compiled the information|wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
5662899	29123532	BH	2	supported the idea|extensively edited the article	supported the idea	Conceived and designed the experiments	Conceptualization	YES
5662899	29123532	BH	2	supported the idea|extensively edited the article	extensively edited the article	Wrote the paper	Writing - Review & Editing	YES
5662899	29123532	HN	2	wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
5662899	29123532	KHMS	2	extensively edited the article	extensively edited the article	Wrote the paper	Writing - Review & Editing	YES
5662899	29123532	KS	2	collected all the literature and compiled the information|wrote the article	collected all the literature and compiled the information	Performed the experiments	Formal analysis|Investigation	YES
5662899	29123532	KS	2	collected all the literature and compiled the information|wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
5662899	29123532	MF	2	gave their valuable inputs in various specialized sections	gave their valuable inputs in various specialized sections	-	-	NO
5662899	29123532	PG	2	gave their valuable inputs in various specialized sections	gave their valuable inputs in various specialized sections	-	-	NO
5662899	29123532	PV	2	gave their valuable inputs in various specialized sections	gave their valuable inputs in various specialized sections	-	-	NO
5662899	29123532	RN	2	gave their valuable inputs in various specialized sections	gave their valuable inputs in various specialized sections	-	-	NO
5662899	29123532	RV	2	gave their valuable inputs in various specialized sections	gave their valuable inputs in various specialized sections	-	-	NO
5662899	29123532	SK	2	gave their valuable inputs in various specialized sections	gave their valuable inputs in various specialized sections	-	-	NO
6432104	30907505	C.J.	2	designed the project and its implementation|providing technical guidance|provided critical review of the article	designed the project and its implementation	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6432104	30907505	C.J.	2	designed the project and its implementation|providing technical guidance|provided critical review of the article	providing technical guidance	-	Supervision	YES
6432104	30907505	C.J.	2	designed the project and its implementation|providing technical guidance|provided critical review of the article	provided critical review of the article	Wrote the paper	Writing - Review & Editing	YES
6432104	30907505	C.N.	2	designed the project and its implementation	designed the project and its implementation	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6432104	30907505	E.L.C.	2	designed the project and its implementation|providing technical guidance|provided critical review of the article	designed the project and its implementation	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6432104	30907505	E.L.C.	2	designed the project and its implementation|providing technical guidance|provided critical review of the article	providing technical guidance	-	Supervision	YES
6432104	30907505	E.L.C.	2	designed the project and its implementation|providing technical guidance|provided critical review of the article	provided critical review of the article	Wrote the paper	Writing - Review & Editing	YES
6432104	30907505	G.S.	2	designed the project and its implementation	designed the project and its implementation	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6432104	30907505	K.H.	2	designed the project and its implementation|completed the first draft with contributions by all co-authors	designed the project and its implementation	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6432104	30907505	K.H.	2	designed the project and its implementation|completed the first draft with contributions by all co-authors	completed the first draft with contributions by all co-authors	Wrote the paper	Writing - Original Draft	YES
6432104	30907505	M.M.	2	designed the project and its implementation	designed the project and its implementation	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6432104	30907505	M.N.	2	designed the project and its implementation	designed the project and its implementation	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6432104	30907505	N.M.	2	designed the project and its implementation	designed the project and its implementation	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6432104	30907505	P.S.	2	designed the project and its implementation	designed the project and its implementation	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6432104	30907505	R.C.	2	designed the project and its implementation	designed the project and its implementation	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6432104	30907505	S.G.	2	designed the project and its implementation	designed the project and its implementation	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6432104	30907505	V.M.	2	designed the project and its implementation	designed the project and its implementation	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4411075	25915490	AA	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411075	25915490	AH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411075	25915490	AH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411075	25915490	AH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411075	25915490	ED	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4411075	25915490	ED	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411075	25915490	ISB	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4411075	25915490	ISB	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411075	25915490	JAH-G	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411075	25915490	JAH-G	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411075	25915490	JAH-G	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411075	25915490	JJB	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4411075	25915490	JJB	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4411075	25915490	RC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411075	25915490	RC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411075	25915490	SG-P	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4411075	25915490	SG-P	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1810432	17356689	BL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1810432	17356689	BL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1810432	17356689	BL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1810432	17356689	BL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1810432	17356689	JB	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1810432	17356689	JB	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3438795	22973314	All authors	2	shaped the final paper	shaped the final paper	-	-	NO
5662918	29123537	BW	2	performed analysis and interpretation of the data	performed analysis and interpretation of the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5662918	29123537	GY	2	designed the experiment|drafted the manuscript	designed the experiment	Conceived and designed the experiments	Methodology	YES
5662918	29123537	GY	2	designed the experiment|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5662918	29123537	KP	2	performed all the phenotypic evaluation	performed all the phenotypic evaluation	Performed the experiments	Investigation	YES
5662918	29123537	LM	2	performed all the phenotypic evaluation|performed analysis and interpretation of the data|drafted the manuscript	performed all the phenotypic evaluation	Performed the experiments	Investigation	YES
5662918	29123537	LM	2	performed all the phenotypic evaluation|performed analysis and interpretation of the data|drafted the manuscript	performed analysis and interpretation of the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5662918	29123537	LM	2	performed all the phenotypic evaluation|performed analysis and interpretation of the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5662918	29123537	QQ	2	designed the experiment	designed the experiment	Conceived and designed the experiments	Methodology	YES
5662918	29123537	The authors	2	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	Performed the experiments	Investigation	YES
5662918	29123537	XZ	2	performed all the phenotypic evaluation|performed analysis and interpretation of the data	performed all the phenotypic evaluation	Performed the experiments	Investigation	YES
5662918	29123537	XZ	2	performed all the phenotypic evaluation|performed analysis and interpretation of the data	performed analysis and interpretation of the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5662918	29123537	all authors	2	revised the paper and approved the final version to be published	revised the paper and approved the final version to be published	Wrote the paper	Writing - Review & Editing	YES
5597726	28871052	C.D.	2	discussed and came up with the general idea of the paper	discussed and came up with the general idea of the paper	Conceived and designed the experiments	Conceptualization	YES
5597726	28871052	D.K.	2	discussed and came up with the general idea of the paper	discussed and came up with the general idea of the paper	Conceived and designed the experiments	Conceptualization	YES
5496347	28673248	ABMC	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5496347	28673248	All authors	PLoS52	contributed to writing of the manuscript and approved the final manuscript	contributed to writing of the manuscript and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5496347	28673248	FRV	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5496347	28673248	HB	PLoS52	conceived and designed the experiments|performed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5496347	28673248	HB	PLoS52	conceived and designed the experiments|performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5496347	28673248	LP	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5496347	28673248	RR	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
6432105	30907491	All authors	2	provided comments on the paper	provided comments on the paper	-	-	NO
6432105	30907491	HAW	2	conceptualized the paper	conceptualized the paper	Conceived and designed the experiments	Conceptualization	YES
6432105	30907491	KF	2	conceptualized the paper	conceptualized the paper	Conceived and designed the experiments	Conceptualization	YES
6432105	30907491	MN	2	conceptualized the paper|wrote the first draft	conceptualized the paper	Conceived and designed the experiments	Conceptualization	YES
6432105	30907491	MN	2	conceptualized the paper|wrote the first draft	wrote the first draft	Wrote the paper	Writing - Original Draft	YES
4411076	25915413	DRM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411076	25915413	MFK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411076	25915413	MFK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411076	25915413	MFK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411076	25915413	MFK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411076	25915413	WAL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411076	25915413	WAL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411076	25915413	WAL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411076	25915413	YQ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411076	25915413	YQ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411076	25915413	YQ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411076	25915413	YQ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411076	25915413	YS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
3311597	22214407	HGW	2	carried out the microbiological experiments and drafted the manuscript	carried out the microbiological experiments and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3311597	22214407	JS	2	determined the optimal experimental conditions and performed chemical analyses	determined the optimal experimental conditions and performed chemical analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3311597	22214407	WK	2	guided structure elucidation and provided all interpretations of the chemical raw data	guided structure elucidation and provided all interpretations of the chemical raw data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources|Supervision	YES
1810433	17375186	CK	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1810433	17375186	FY	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1810433	17375186	MO	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1810433	17375186	MO	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1810433	17375186	MO	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1810433	17375186	XG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5662920	29123539	JIR-O	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5662920	29123539	JS	2	performed experiments, prepared figures, wrote parts, and revised the manuscript	performed experiments, prepared figures, wrote parts, and revised the manuscript	Performed the experiments|Wrote the paper	Investigation|Visualization|Writing - Original Draft|Writing - Review & Editing	YES
5662920	29123539	NM-M	2	conceptualized the research, designed experiments, participated in writing, editing, and revising the manuscript	conceptualized the research, designed experiments, participated in writing, editing, and revising the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5662920	29123539	SdF	2	conceptualized the research, designed experiments, participated in writing, editing, and revising the manuscript	conceptualized the research, designed experiments, participated in writing, editing, and revising the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5662920	29123539	YD-M	2	conceptualized the research, designed and performed experiments, wrote the original drafts, and prepared figures	conceptualized the research, designed and performed experiments, wrote the original drafts, and prepared figures	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Visualization|Writing - Original Draft	YES
6432106	30907499	CJ	2	drafted the manuscript and revised it critically|supervised the study and facilitated the acquisition of the cost data	drafted the manuscript and revised it critically	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6432106	30907499	CJ	2	drafted the manuscript and revised it critically|supervised the study and facilitated the acquisition of the cost data	supervised the study and facilitated the acquisition of the cost data	Performed the experiments	Investigation|Supervision	YES
6432106	30907499	CM	2	conceptualized and designed the study|collected and facilitated the collection of data|analysed and interpreted the data|drafted the manuscript and revised it critically	conceptualized and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6432106	30907499	CM	2	conceptualized and designed the study|collected and facilitated the collection of data|analysed and interpreted the data|drafted the manuscript and revised it critically	collected and facilitated the collection of data	Performed the experiments	Investigation	YES
6432106	30907499	CM	2	conceptualized and designed the study|collected and facilitated the collection of data|analysed and interpreted the data|drafted the manuscript and revised it critically	analysed and interpreted the data	Analyzed the data	Formal analysis	YES
6432106	30907499	CM	2	conceptualized and designed the study|collected and facilitated the collection of data|analysed and interpreted the data|drafted the manuscript and revised it critically	drafted the manuscript and revised it critically	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6432106	30907499	ELC	2	drafted the manuscript and revised it critically|supervised the study and facilitated the acquisition of the cost data	drafted the manuscript and revised it critically	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6432106	30907499	ELC	2	drafted the manuscript and revised it critically|supervised the study and facilitated the acquisition of the cost data	supervised the study and facilitated the acquisition of the cost data	Performed the experiments	Investigation|Supervision	YES
6432106	30907499	ELS	2	drafted the manuscript and revised it critically|supervised the study and facilitated the acquisition of the cost data	drafted the manuscript and revised it critically	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6432106	30907499	ELS	2	drafted the manuscript and revised it critically|supervised the study and facilitated the acquisition of the cost data	supervised the study and facilitated the acquisition of the cost data	Performed the experiments	Investigation|Supervision	YES
6432106	30907499	FC	2	drafted the manuscript and revised it critically|supervised the study and facilitated the acquisition of the cost data	drafted the manuscript and revised it critically	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6432106	30907499	FC	2	drafted the manuscript and revised it critically|supervised the study and facilitated the acquisition of the cost data	supervised the study and facilitated the acquisition of the cost data	Performed the experiments	Investigation|Supervision	YES
6432106	30907499	FTP	2	conceptualized and designed the study|analysed and interpreted the data|drafted the manuscript and revised it critically|supervised the study and facilitated the acquisition of the cost data	conceptualized and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6432106	30907499	FTP	2	conceptualized and designed the study|analysed and interpreted the data|drafted the manuscript and revised it critically|supervised the study and facilitated the acquisition of the cost data	analysed and interpreted the data	Analyzed the data	Formal analysis	YES
6432106	30907499	FTP	2	conceptualized and designed the study|analysed and interpreted the data|drafted the manuscript and revised it critically|supervised the study and facilitated the acquisition of the cost data	drafted the manuscript and revised it critically	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6432106	30907499	FTP	2	conceptualized and designed the study|analysed and interpreted the data|drafted the manuscript and revised it critically|supervised the study and facilitated the acquisition of the cost data	supervised the study and facilitated the acquisition of the cost data	Performed the experiments	Investigation|Supervision	YES
6432106	30907499	GN	2	drafted the manuscript and revised it critically|supervised the study and facilitated the acquisition of the cost data	drafted the manuscript and revised it critically	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6432106	30907499	GN	2	drafted the manuscript and revised it critically|supervised the study and facilitated the acquisition of the cost data	supervised the study and facilitated the acquisition of the cost data	Performed the experiments	Investigation|Supervision	YES
6432106	30907499	HA	2	drafted the manuscript and revised it critically|supervised the study and facilitated the acquisition of the cost data	drafted the manuscript and revised it critically	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6432106	30907499	HA	2	drafted the manuscript and revised it critically|supervised the study and facilitated the acquisition of the cost data	supervised the study and facilitated the acquisition of the cost data	Performed the experiments	Investigation|Supervision	YES
6432106	30907499	HM	2	conceptualized and designed the study|analysed and interpreted the data|drafted the manuscript and revised it critically|supervised the study and facilitated the acquisition of the cost data	conceptualized and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6432106	30907499	HM	2	conceptualized and designed the study|analysed and interpreted the data|drafted the manuscript and revised it critically|supervised the study and facilitated the acquisition of the cost data	analysed and interpreted the data	Analyzed the data	Formal analysis	YES
6432106	30907499	HM	2	conceptualized and designed the study|analysed and interpreted the data|drafted the manuscript and revised it critically|supervised the study and facilitated the acquisition of the cost data	drafted the manuscript and revised it critically	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6432106	30907499	HM	2	conceptualized and designed the study|analysed and interpreted the data|drafted the manuscript and revised it critically|supervised the study and facilitated the acquisition of the cost data	supervised the study and facilitated the acquisition of the cost data	Performed the experiments	Investigation|Supervision	YES
6432106	30907499	JJO	2	analysed and interpreted the data|drafted the manuscript and revised it critically	analysed and interpreted the data	Analyzed the data	Formal analysis	YES
6432106	30907499	JJO	2	analysed and interpreted the data|drafted the manuscript and revised it critically	drafted the manuscript and revised it critically	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6432106	30907499	KH	2	drafted the manuscript and revised it critically|supervised the study and facilitated the acquisition of the cost data	drafted the manuscript and revised it critically	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6432106	30907499	KH	2	drafted the manuscript and revised it critically|supervised the study and facilitated the acquisition of the cost data	supervised the study and facilitated the acquisition of the cost data	Performed the experiments	Investigation|Supervision	YES
6432106	30907499	LM	2	conceptualized and designed the study|collected and facilitated the collection of data|analysed and interpreted the data|drafted the manuscript and revised it critically	conceptualized and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6432106	30907499	LM	2	conceptualized and designed the study|collected and facilitated the collection of data|analysed and interpreted the data|drafted the manuscript and revised it critically	collected and facilitated the collection of data	Performed the experiments	Investigation	YES
6432106	30907499	LM	2	conceptualized and designed the study|collected and facilitated the collection of data|analysed and interpreted the data|drafted the manuscript and revised it critically	analysed and interpreted the data	Analyzed the data	Formal analysis	YES
6432106	30907499	LM	2	conceptualized and designed the study|collected and facilitated the collection of data|analysed and interpreted the data|drafted the manuscript and revised it critically	drafted the manuscript and revised it critically	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6432106	30907499	LS	2	conceptualized and designed the study|collected and facilitated the collection of data|analysed and interpreted the data|drafted the manuscript and revised it critically	conceptualized and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6432106	30907499	LS	2	conceptualized and designed the study|collected and facilitated the collection of data|analysed and interpreted the data|drafted the manuscript and revised it critically	collected and facilitated the collection of data	Performed the experiments	Investigation	YES
6432106	30907499	LS	2	conceptualized and designed the study|collected and facilitated the collection of data|analysed and interpreted the data|drafted the manuscript and revised it critically	analysed and interpreted the data	Analyzed the data	Formal analysis	YES
6432106	30907499	LS	2	conceptualized and designed the study|collected and facilitated the collection of data|analysed and interpreted the data|drafted the manuscript and revised it critically	drafted the manuscript and revised it critically	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6432106	30907499	MD	2	conceptualized and designed the study|analysed and interpreted the data|drafted the manuscript and revised it critically	conceptualized and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6432106	30907499	MD	2	conceptualized and designed the study|analysed and interpreted the data|drafted the manuscript and revised it critically	analysed and interpreted the data	Analyzed the data	Formal analysis	YES
6432106	30907499	MD	2	conceptualized and designed the study|analysed and interpreted the data|drafted the manuscript and revised it critically	drafted the manuscript and revised it critically	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6432106	30907499	MM	2	drafted the manuscript and revised it critically|supervised the study and facilitated the acquisition of the cost data	drafted the manuscript and revised it critically	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6432106	30907499	MM	2	drafted the manuscript and revised it critically|supervised the study and facilitated the acquisition of the cost data	supervised the study and facilitated the acquisition of the cost data	Performed the experiments	Investigation|Supervision	YES
6432106	30907499	MN	2	drafted the manuscript and revised it critically|supervised the study and facilitated the acquisition of the cost data	drafted the manuscript and revised it critically	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6432106	30907499	MN	2	drafted the manuscript and revised it critically|supervised the study and facilitated the acquisition of the cost data	supervised the study and facilitated the acquisition of the cost data	Performed the experiments	Investigation|Supervision	YES
6432106	30907499	MNE	2	drafted the manuscript and revised it critically|supervised the study and facilitated the acquisition of the cost data	drafted the manuscript and revised it critically	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6432106	30907499	MNE	2	drafted the manuscript and revised it critically|supervised the study and facilitated the acquisition of the cost data	supervised the study and facilitated the acquisition of the cost data	Performed the experiments	Investigation|Supervision	YES
6432106	30907499	NA	2	conceptualized and designed the study|collected and facilitated the collection of data|analysed and interpreted the data|drafted the manuscript and revised it critically	conceptualized and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6432106	30907499	NA	2	conceptualized and designed the study|collected and facilitated the collection of data|analysed and interpreted the data|drafted the manuscript and revised it critically	collected and facilitated the collection of data	Performed the experiments	Investigation	YES
6432106	30907499	NA	2	conceptualized and designed the study|collected and facilitated the collection of data|analysed and interpreted the data|drafted the manuscript and revised it critically	analysed and interpreted the data	Analyzed the data	Formal analysis	YES
6432106	30907499	NA	2	conceptualized and designed the study|collected and facilitated the collection of data|analysed and interpreted the data|drafted the manuscript and revised it critically	drafted the manuscript and revised it critically	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6432106	30907499	OM	2	drafted the manuscript and revised it critically|supervised the study and facilitated the acquisition of the cost data	drafted the manuscript and revised it critically	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6432106	30907499	OM	2	drafted the manuscript and revised it critically|supervised the study and facilitated the acquisition of the cost data	supervised the study and facilitated the acquisition of the cost data	Performed the experiments	Investigation|Supervision	YES
6432106	30907499	PC	2	collected and facilitated the collection of data|analysed and interpreted the data|drafted the manuscript and revised it critically	collected and facilitated the collection of data	Performed the experiments	Investigation	YES
6432106	30907499	PC	2	collected and facilitated the collection of data|analysed and interpreted the data|drafted the manuscript and revised it critically	analysed and interpreted the data	Analyzed the data	Formal analysis	YES
6432106	30907499	PC	2	collected and facilitated the collection of data|analysed and interpreted the data|drafted the manuscript and revised it critically	drafted the manuscript and revised it critically	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6432106	30907499	PI	2	drafted the manuscript and revised it critically|supervised the study and facilitated the acquisition of the cost data	drafted the manuscript and revised it critically	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6432106	30907499	PI	2	drafted the manuscript and revised it critically|supervised the study and facilitated the acquisition of the cost data	supervised the study and facilitated the acquisition of the cost data	Performed the experiments	Investigation|Supervision	YES
6432106	30907499	RC	2	drafted the manuscript and revised it critically|supervised the study and facilitated the acquisition of the cost data	drafted the manuscript and revised it critically	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6432106	30907499	RC	2	drafted the manuscript and revised it critically|supervised the study and facilitated the acquisition of the cost data	supervised the study and facilitated the acquisition of the cost data	Performed the experiments	Investigation|Supervision	YES
6432106	30907499	SK	2	collected and facilitated the collection of data|analysed and interpreted the data|drafted the manuscript and revised it critically	collected and facilitated the collection of data	Performed the experiments	Investigation	YES
6432106	30907499	SK	2	collected and facilitated the collection of data|analysed and interpreted the data|drafted the manuscript and revised it critically	analysed and interpreted the data	Analyzed the data	Formal analysis	YES
6432106	30907499	SK	2	collected and facilitated the collection of data|analysed and interpreted the data|drafted the manuscript and revised it critically	drafted the manuscript and revised it critically	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6432106	30907499	TC	2	collected and facilitated the collection of data|analysed and interpreted the data|drafted the manuscript and revised it critically	collected and facilitated the collection of data	Performed the experiments	Investigation	YES
6432106	30907499	TC	2	collected and facilitated the collection of data|analysed and interpreted the data|drafted the manuscript and revised it critically	analysed and interpreted the data	Analyzed the data	Formal analysis	YES
6432106	30907499	TC	2	collected and facilitated the collection of data|analysed and interpreted the data|drafted the manuscript and revised it critically	drafted the manuscript and revised it critically	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4411077	25915059	EOM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411077	25915059	EOM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411077	25915059	EOM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411077	25915059	EOM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411077	25915059	EPI	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4411077	25915059	EPI	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411077	25915059	JAAR	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4411077	25915059	JAAR	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4411077	25915059	JCP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411077	25915059	JCP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411077	25915059	JCP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411077	25915059	JCP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411077	25915059	JCP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411077	25915059	OABM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411077	25915059	OABM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411077	25915059	OABM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411077	25915059	OABM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1810434	17375187	AA	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1810434	17375187	CY	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1810434	17375187	DV	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1810434	17375187	DV	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1810434	17375187	DV	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1810434	17375187	IL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1810434	17375187	IL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1810434	17375187	IL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1810434	17375187	JF	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1810434	17375187	LF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1810434	17375187	LF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1810434	17375187	LF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1810434	17375187	LF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1810434	17375187	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1810434	17375187	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1810434	17375187	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1810434	17375187	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1810434	17375187	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1810434	17375187	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1810434	17375187	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1810434	17375187	XP	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1810434	17375187	XP	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5686400	29133442	A.R.G.M.	2	expanded the concept and did the simulations	expanded the concept and did the simulations	Conceived and designed the experiments	Conceptualization|Formal analysis	YES
5686400	29133442	All the authors	2	wrote the paper together	wrote the paper together	Wrote the paper	Writing - Original Draft	YES
5686400	29133442	S.M.M.	2	who then together built the algorithm|expanded the concept and did the simulations	who then together built the algorithm	Contributed reagents/materials/analysis tools	Software	YES
5686400	29133442	S.M.M.	2	who then together built the algorithm|expanded the concept and did the simulations	expanded the concept and did the simulations	Conceived and designed the experiments	Conceptualization|Formal analysis	YES
5496360	28673252	ASMC	2	participated in the experimental design|performed data analysis|collaborated with interpretation and discussion of the results	participated in the experimental design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5496360	28673252	ASMC	2	participated in the experimental design|performed data analysis|collaborated with interpretation and discussion of the results	performed data analysis	Analyzed the data	Formal analysis	YES
5496360	28673252	ASMC	2	participated in the experimental design|performed data analysis|collaborated with interpretation and discussion of the results	collaborated with interpretation and discussion of the results	Analyzed the data	Formal analysis	YES
5496360	28673252	BSV	2	participated in the experimental design|performed data analysis|drafted the manuscript|collaborated with interpretation and discussion of the results	participated in the experimental design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5496360	28673252	BSV	2	participated in the experimental design|performed data analysis|drafted the manuscript|collaborated with interpretation and discussion of the results	performed data analysis	Analyzed the data	Formal analysis	YES
5496360	28673252	BSV	2	participated in the experimental design|performed data analysis|drafted the manuscript|collaborated with interpretation and discussion of the results	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5496360	28673252	BSV	2	participated in the experimental design|performed data analysis|drafted the manuscript|collaborated with interpretation and discussion of the results	collaborated with interpretation and discussion of the results	Analyzed the data	Formal analysis	YES
5496360	28673252	JCCB	2	collaborated with interpretation and discussion of the results|provided the experimental environment and coordination	collaborated with interpretation and discussion of the results	Analyzed the data	Formal analysis	YES
5496360	28673252	JCCB	2	collaborated with interpretation and discussion of the results|provided the experimental environment and coordination	provided the experimental environment and coordination	-	Project administration	YES
5496360	28673252	LCAR	2	collaborated with interpretation and discussion of the results|provided the experimental environment and coordination	collaborated with interpretation and discussion of the results	Analyzed the data	Formal analysis	YES
5496360	28673252	LCAR	2	collaborated with interpretation and discussion of the results|provided the experimental environment and coordination	provided the experimental environment and coordination	-	Project administration	YES
5496360	28673252	LLC	2	collaborated with interpretation and discussion of the results|provided the experimental environment and coordination	collaborated with interpretation and discussion of the results	Analyzed the data	Formal analysis	YES
5496360	28673252	LLC	2	collaborated with interpretation and discussion of the results|provided the experimental environment and coordination	provided the experimental environment and coordination	-	Project administration	YES
5496360	28673252	MDP	2	participated in the experimental design|performed data analysis|collaborated with interpretation and discussion of the results	participated in the experimental design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5496360	28673252	MDP	2	participated in the experimental design|performed data analysis|collaborated with interpretation and discussion of the results	performed data analysis	Analyzed the data	Formal analysis	YES
5496360	28673252	MDP	2	participated in the experimental design|performed data analysis|collaborated with interpretation and discussion of the results	collaborated with interpretation and discussion of the results	Analyzed the data	Formal analysis	YES
4564617	26413529	Dilek Ongan	2	prepared the paper	prepared the paper	Wrote the paper	Writing - Original Draft	YES
4564617	26413529	Gulsah Kaner	2	prepared the paper	prepared the paper	Wrote the paper	Writing - Original Draft	YES
4564617	26413529	Meltem Soylu	2	prepared the paper	prepared the paper	Wrote the paper	Writing - Original Draft	YES
4564617	26413529	Neriman Inanc	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
4564617	26413529	Nimet Yuksel	2	designed the study|collected the data	designed the study	Conceived and designed the experiments	Methodology	YES
4564617	26413529	Nimet Yuksel	2	designed the study|collected the data	collected the data	Performed the experiments	Investigation	YES
5662930	29123533	BM	2	designed the study, analyzed the data and wrote the manuscript	designed the study, analyzed the data and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5662930	29123533	BMO	2	collected the data, analyzed the data and contributed to the writing of the manuscript	collected the data, analyzed the data and contributed to the writing of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5662930	29123533	GF	2	collected the data	collected the data	Performed the experiments	Investigation	YES
5662930	29123533	YG	2	designed and implemented the statistical models, analyzed the data and wrote the manuscript	designed and implemented the statistical models, analyzed the data and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
1817752	17375194	DF	PLoS5	Discussed the study motivation and scope, reviewed the paper	Discussed the study motivation and scope, reviewed the paper	Wrote the paper	Writing - Review & Editing	YES
1817752	17375194	HP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1817752	17375194	HP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1817752	17375194	HP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1817752	17375194	HP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1817752	17375194	RD	PLoS5	Reviewed the data analysis and interpretation, reviewed the paper	Reviewed the data analysis and interpretation, reviewed the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4411078	25915065	BL	PLoS5	Supervisor of project application fundings	Supervisor of project application fundings	-	Funding acquisition|Supervision	YES
4411078	25915065	BP	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411078	25915065	EB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411078	25915065	F. Cesca	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411078	25915065	F. Cesca	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411078	25915065	F. Cesca	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411078	25915065	F. Cesca	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411078	25915065	F. Curcio	PLoS5	Paper revision and editing	Paper revision and editing	Wrote the paper	Writing - Review & Editing	YES
4411078	25915065	GB	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411078	25915065	GD	PLoS5	Paper revision and editing	Paper revision and editing	Wrote the paper	Writing - Review & Editing	YES
4411078	25915065	GDdW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411078	25915065	GP	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411078	25915065	GS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411078	25915065	IRL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411078	25915065	IRL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411078	25915065	IRL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411078	25915065	LP	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411078	25915065	LV	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411078	25915065	MZ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411078	25915065	PB	PLoS5	Partial enrollment of patients	Partial enrollment of patients	Performed the experiments	Investigation	YES
4411078	25915065	RC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
6432108	30907498	AP	2	substantially contributed to the formulation of research question and conceptualized the study|worked on development and programming of the hiv synthesis model|analysed the simulations|drafted the manuscript or critically revising it for important intellectual content	substantially contributed to the formulation of research question and conceptualized the study	Conceived and designed the experiments	Conceptualization	YES
6432108	30907498	AP	2	substantially contributed to the formulation of research question and conceptualized the study|worked on development and programming of the hiv synthesis model|analysed the simulations|drafted the manuscript or critically revising it for important intellectual content	worked on development and programming of the hiv synthesis model	Performed the experiments|Contributed reagents/materials/analysis tools	Methodology|Software	YES
6432108	30907498	AP	2	substantially contributed to the formulation of research question and conceptualized the study|worked on development and programming of the hiv synthesis model|analysed the simulations|drafted the manuscript or critically revising it for important intellectual content	analysed the simulations	-	Formal analysis	YES
6432108	30907498	AP	2	substantially contributed to the formulation of research question and conceptualized the study|worked on development and programming of the hiv synthesis model|analysed the simulations|drafted the manuscript or critically revising it for important intellectual content	drafted the manuscript or critically revising it for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6432108	30907498	All authors	2	gave final approval of the version to be published	gave final approval of the version to be published	-	-	NO
6432108	30907498	CF	2	drafted the manuscript or critically revising it for important intellectual content	drafted the manuscript or critically revising it for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6432108	30907498	CJ	2	substantially contributed to the formulation of research question and conceptualized the study|drafted the manuscript or critically revising it for important intellectual content	substantially contributed to the formulation of research question and conceptualized the study	Conceived and designed the experiments	Conceptualization	YES
6432108	30907498	CJ	2	substantially contributed to the formulation of research question and conceptualized the study|drafted the manuscript or critically revising it for important intellectual content	drafted the manuscript or critically revising it for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6432108	30907498	ES	2	drafted the manuscript or critically revising it for important intellectual content	drafted the manuscript or critically revising it for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6432108	30907498	FC	2	substantially contributed to the formulation of research question and conceptualized the study|drafted the manuscript or critically revising it for important intellectual content	substantially contributed to the formulation of research question and conceptualized the study	Conceived and designed the experiments	Conceptualization	YES
6432108	30907498	FC	2	substantially contributed to the formulation of research question and conceptualized the study|drafted the manuscript or critically revising it for important intellectual content	drafted the manuscript or critically revising it for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6432108	30907498	FTP	2	substantially contributed to the formulation of research question and conceptualized the study|drafted the manuscript or critically revising it for important intellectual content	substantially contributed to the formulation of research question and conceptualized the study	Conceived and designed the experiments	Conceptualization	YES
6432108	30907498	FTP	2	substantially contributed to the formulation of research question and conceptualized the study|drafted the manuscript or critically revising it for important intellectual content	drafted the manuscript or critically revising it for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6432108	30907498	GN	2	drafted the manuscript or critically revising it for important intellectual content	drafted the manuscript or critically revising it for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6432108	30907498	HM	2	drafted the manuscript or critically revising it for important intellectual content	drafted the manuscript or critically revising it for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6432108	30907498	KH	2	substantially contributed to the formulation of research question and conceptualized the study|drafted the manuscript or critically revising it for important intellectual content	substantially contributed to the formulation of research question and conceptualized the study	Conceived and designed the experiments	Conceptualization	YES
6432108	30907498	KH	2	substantially contributed to the formulation of research question and conceptualized the study|drafted the manuscript or critically revising it for important intellectual content	drafted the manuscript or critically revising it for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6432108	30907498	LC	2	substantially contributed to the formulation of research question and conceptualized the study|drafted the manuscript or critically revising it for important intellectual content	substantially contributed to the formulation of research question and conceptualized the study	Conceived and designed the experiments	Conceptualization	YES
6432108	30907498	LC	2	substantially contributed to the formulation of research question and conceptualized the study|drafted the manuscript or critically revising it for important intellectual content	drafted the manuscript or critically revising it for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6432108	30907498	PR	2	substantially contributed to the formulation of research question and conceptualized the study|drafted the manuscript or critically revising it for important intellectual content	substantially contributed to the formulation of research question and conceptualized the study	Conceived and designed the experiments	Conceptualization	YES
6432108	30907498	PR	2	substantially contributed to the formulation of research question and conceptualized the study|drafted the manuscript or critically revising it for important intellectual content	drafted the manuscript or critically revising it for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6432108	30907498	RCB	2	drafted the manuscript or critically revising it for important intellectual content	drafted the manuscript or critically revising it for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6432108	30907498	TH	2	drafted the manuscript or critically revising it for important intellectual content	drafted the manuscript or critically revising it for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6432108	30907498	VC	2	substantially contributed to the formulation of research question and conceptualized the study|worked on development and programming of the hiv synthesis model|performed the modelling analysis|analysed the simulations|drafted the manuscript or critically revising it for important intellectual content	substantially contributed to the formulation of research question and conceptualized the study	Conceived and designed the experiments	Conceptualization	YES
6432108	30907498	VC	2	substantially contributed to the formulation of research question and conceptualized the study|worked on development and programming of the hiv synthesis model|performed the modelling analysis|analysed the simulations|drafted the manuscript or critically revising it for important intellectual content	worked on development and programming of the hiv synthesis model	Performed the experiments|Contributed reagents/materials/analysis tools	Methodology|Software	YES
6432108	30907498	VC	2	substantially contributed to the formulation of research question and conceptualized the study|worked on development and programming of the hiv synthesis model|performed the modelling analysis|analysed the simulations|drafted the manuscript or critically revising it for important intellectual content	performed the modelling analysis	Performed the experiments	Investigation|Methodology	YES
6432108	30907498	VC	2	substantially contributed to the formulation of research question and conceptualized the study|worked on development and programming of the hiv synthesis model|performed the modelling analysis|analysed the simulations|drafted the manuscript or critically revising it for important intellectual content	analysed the simulations	-	Formal analysis	YES
6432108	30907498	VC	2	substantially contributed to the formulation of research question and conceptualized the study|worked on development and programming of the hiv synthesis model|performed the modelling analysis|analysed the simulations|drafted the manuscript or critically revising it for important intellectual content	drafted the manuscript or critically revising it for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5686402	29133444	Both authors	2	gave their final approval for publication	gave their final approval for publication	-	-	NO
5686402	29133444	H.J.C.	2	carried out the computational design and evaluation, participated in data analysis, participated in the design of the study and drafted the manuscript	carried out the computational design and evaluation, participated in data analysis, participated in the design of the study and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5686402	29133444	M.M.	2	carried out the computational design and evaluation, participated in data analysis, participated in the design of the study and drafted the manuscript	carried out the computational design and evaluation, participated in data analysis, participated in the design of the study and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5663686	29163564	AS	2	designed and planned the research|performed sequence comparisons and prepared figures|wrote the manuscript and approved the version to be published	designed and planned the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5663686	29163564	AS	2	designed and planned the research|performed sequence comparisons and prepared figures|wrote the manuscript and approved the version to be published	performed sequence comparisons and prepared figures	Performed the experiments	Investigation|Visualization	YES
5663686	29163564	AS	2	designed and planned the research|performed sequence comparisons and prepared figures|wrote the manuscript and approved the version to be published	wrote the manuscript and approved the version to be published	Wrote the paper	Writing - Original Draft	YES
5663686	29163564	SM	2	designed and planned the research|performed database searches|wrote the manuscript and approved the version to be published	designed and planned the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5663686	29163564	SM	2	designed and planned the research|performed database searches|wrote the manuscript and approved the version to be published	performed database searches	Contributed reagents/materials/analysis tools	Software	YES
5663686	29163564	SM	2	designed and planned the research|performed database searches|wrote the manuscript and approved the version to be published	wrote the manuscript and approved the version to be published	Wrote the paper	Writing - Original Draft	YES
4411086	25915900	DPN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411086	25915900	DPN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411086	25915900	DPN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411086	25915900	DPN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411086	25915900	EGU	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411086	25915900	EGU	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411086	25915900	EGU	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411086	25915900	MLN	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411086	25915900	MMB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411086	25915900	RM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411086	25915900	RM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411086	25915900	RM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411086	25915900	RM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411086	25915900	RM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411086	25915900	SB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411086	25915900	YR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411086	25915900	YR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411086	25915900	YR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411086	25915900	YR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1819555	17375199	AB	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1819555	17375199	AB	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1819555	17375199	BF	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1819555	17375199	BF	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1819555	17375199	BF	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1819555	17375199	BP	PLoS5	Head of the research unit	Head of the research unit	-	-	NO
1819555	17375199	CG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1819555	17375199	CG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1819555	17375199	CG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1819555	17375199	CG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1819555	17375199	FC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1819555	17375199	GZ	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1819555	17375199	GZ	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1819555	17375199	JD	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1819555	17375199	JD	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1819555	17375199	JS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5497376	28676109	ER	2	performed bioinformatic analyses and analysed the data	performed bioinformatic analyses and analysed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5497376	28676109	LO	2	performed bioinformatic analyses and analysed the data	performed bioinformatic analyses and analysed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5497376	28676109	MB	2	conceived the study, analysed the data and wrote the manuscript	conceived the study, analysed the data and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
5497376	28676109	PM	2	performed bioinformatic analyses, analysed the data and wrote the manuscript	performed bioinformatic analyses, analysed the data and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5497376	28676109	RCL	2	performed qrt-pcr analyses and analysed the data	performed qrt-pcr analyses and analysed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5497376	28676109	RvR	2	conceived the study and wrote the manuscript	conceived the study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5497376	28676109	UP	2	performed bioinformatic analyses and analysed the data	performed bioinformatic analyses and analysed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5497376	28676109	ZT	2	performed bioinformatic analyses, analysed the data and wrote the manuscript	performed bioinformatic analyses, analysed the data and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6432109	30907513	CJ	2	were involved in the concept and design of the study and reviewed the manuscript	were involved in the concept and design of the study and reviewed the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
6432109	30907513	ELC	2	were involved in the concept and design of the study and reviewed the manuscript	were involved in the concept and design of the study and reviewed the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
6432109	30907513	KH	2	were involved in the concept and design of the study and reviewed the manuscript	were involved in the concept and design of the study and reviewed the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
6432109	30907513	LN	2	was involved in the design and data collection portion of the study and contributed to the writing of the manuscript	was involved in the design and data collection portion of the study and contributed to the writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
6432109	30907513	MS	2	were involved in the data collection portion of the study and reviewed the manuscript	were involved in the data collection portion of the study and reviewed the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
6432109	30907513	MT	2	was involved in the concept, design and analysis of the study and contributed to the writing of the manuscript	was involved in the concept, design and analysis of the study and contributed to the writing of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
6432109	30907513	RD	2	was involved in the concept, design, data collection and management, analysis of study data and led the writing of the manuscript	was involved in the concept, design, data collection and management, analysis of study data and led the writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Data curation|Formal analysis|Investigation|Methodology|Project administration|Writing - Original Draft	YES
6432109	30907513	VW	2	was involved in the concept, design, data collection and management of the study and contributed to the writing of the manuscript	was involved in the concept, design, data collection and management of the study and contributed to the writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Project administration|Writing - Original Draft	YES
5686408	29133450	All authors	2	analysed the data, contributed to writing the final manuscript and gave final approval for publication	analysed the data, contributed to writing the final manuscript and gave final approval for publication	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5663689	29163569	AM	2	approved the version to be published	approved the version to be published	-	-	NO
5663689	29163569	CC	2	approved the version to be published	approved the version to be published	-	-	NO
5663689	29163569	DM	2	contributed substantially to the conception and design of the review|drafted the text|approved the version to be published|agreed to be accountable for all aspects of the work	contributed substantially to the conception and design of the review	Conceived and designed the experiments	Conceptualization	YES
5663689	29163569	DM	2	contributed substantially to the conception and design of the review|drafted the text|approved the version to be published|agreed to be accountable for all aspects of the work	drafted the text	Wrote the paper	Writing - Original Draft	YES
5663689	29163569	DM	2	contributed substantially to the conception and design of the review|drafted the text|approved the version to be published|agreed to be accountable for all aspects of the work	approved the version to be published	-	-	NO
5663689	29163569	DM	2	contributed substantially to the conception and design of the review|drafted the text|approved the version to be published|agreed to be accountable for all aspects of the work	agreed to be accountable for all aspects of the work	-	-	NO
5663689	29163569	GG	2	contributed substantially to the conception and design of the review|approved the version to be published	contributed substantially to the conception and design of the review	Conceived and designed the experiments	Conceptualization	YES
5663689	29163569	GG	2	contributed substantially to the conception and design of the review|approved the version to be published	approved the version to be published	-	-	NO
5663689	29163569	MR	2	contributed substantially to the conception and design of the review|drafted the text|approved the version to be published|agreed to be accountable for all aspects of the work	contributed substantially to the conception and design of the review	Conceived and designed the experiments	Conceptualization	YES
5663689	29163569	MR	2	contributed substantially to the conception and design of the review|drafted the text|approved the version to be published|agreed to be accountable for all aspects of the work	drafted the text	Wrote the paper	Writing - Original Draft	YES
5663689	29163569	MR	2	contributed substantially to the conception and design of the review|drafted the text|approved the version to be published|agreed to be accountable for all aspects of the work	approved the version to be published	-	-	NO
5663689	29163569	MR	2	contributed substantially to the conception and design of the review|drafted the text|approved the version to be published|agreed to be accountable for all aspects of the work	agreed to be accountable for all aspects of the work	-	-	NO
5663689	29163569	MT	2	contributed substantially to the conception and design of the review|drafted the text|approved the version to be published|agreed to be accountable for all aspects of the work	contributed substantially to the conception and design of the review	Conceived and designed the experiments	Conceptualization	YES
5663689	29163569	MT	2	contributed substantially to the conception and design of the review|drafted the text|approved the version to be published|agreed to be accountable for all aspects of the work	drafted the text	Wrote the paper	Writing - Original Draft	YES
5663689	29163569	MT	2	contributed substantially to the conception and design of the review|drafted the text|approved the version to be published|agreed to be accountable for all aspects of the work	approved the version to be published	-	-	NO
5663689	29163569	MT	2	contributed substantially to the conception and design of the review|drafted the text|approved the version to be published|agreed to be accountable for all aspects of the work	agreed to be accountable for all aspects of the work	-	-	NO
5663689	29163569	PP	2	contributed substantially to the conception and design of the review|drafted the text|approved the version to be published|agreed to be accountable for all aspects of the work	contributed substantially to the conception and design of the review	Conceived and designed the experiments	Conceptualization	YES
5663689	29163569	PP	2	contributed substantially to the conception and design of the review|drafted the text|approved the version to be published|agreed to be accountable for all aspects of the work	drafted the text	Wrote the paper	Writing - Original Draft	YES
5663689	29163569	PP	2	contributed substantially to the conception and design of the review|drafted the text|approved the version to be published|agreed to be accountable for all aspects of the work	approved the version to be published	-	-	NO
5663689	29163569	PP	2	contributed substantially to the conception and design of the review|drafted the text|approved the version to be published|agreed to be accountable for all aspects of the work	agreed to be accountable for all aspects of the work	-	-	NO
5663689	29163569	PS	2	contributed substantially to the conception and design of the review|drafted the text|approved the version to be published|agreed to be accountable for all aspects of the work	contributed substantially to the conception and design of the review	Conceived and designed the experiments	Conceptualization	YES
5663689	29163569	PS	2	contributed substantially to the conception and design of the review|drafted the text|approved the version to be published|agreed to be accountable for all aspects of the work	drafted the text	Wrote the paper	Writing - Original Draft	YES
5663689	29163569	PS	2	contributed substantially to the conception and design of the review|drafted the text|approved the version to be published|agreed to be accountable for all aspects of the work	approved the version to be published	-	-	NO
5663689	29163569	PS	2	contributed substantially to the conception and design of the review|drafted the text|approved the version to be published|agreed to be accountable for all aspects of the work	agreed to be accountable for all aspects of the work	-	-	NO
5663689	29163569	RB	2	approved the version to be published	approved the version to be published	-	-	NO
5719219	29175905	A.M.B.	4	Data acquisition was performed by|data interpretation by|The manuscript was written by	Data acquisition was performed by	Performed the experiments	Investigation	YES
5719219	29175905	A.M.B.	4	Data acquisition was performed by|data interpretation by|The manuscript was written by	data interpretation by	Analyzed the data	Formal analysis	YES
5719219	29175905	A.M.B.	4	Data acquisition was performed by|data interpretation by|The manuscript was written by	The manuscript was written by	Wrote the paper	Writing - Original Draft	YES
5719219	29175905	A.V.	4	Data acquisition was performed by|data analysis by	Data acquisition was performed by	Performed the experiments	Investigation	YES
5719219	29175905	A.V.	4	Data acquisition was performed by|data analysis by	data analysis by	Analyzed the data	Formal analysis	YES
5719219	29175905	J.F.W.M.	4	Data acquisition was performed by	Data acquisition was performed by	Performed the experiments	Investigation	YES
5719219	29175905	J.P.	4	Sample preparation was performed by	Sample preparation was performed by	Performed the experiments	Investigation	YES
5719219	29175905	M.D.M.	4	Data acquisition was performed by	Data acquisition was performed by	Performed the experiments	Investigation	YES
5719219	29175905	P.S.	4	Data acquisition was performed by|data analysis by|data interpretation by	Data acquisition was performed by	Performed the experiments	Investigation	YES
5719219	29175905	P.S.	4	Data acquisition was performed by|data analysis by|data interpretation by	data analysis by	Analyzed the data	Formal analysis	YES
5719219	29175905	P.S.	4	Data acquisition was performed by|data analysis by|data interpretation by	data interpretation by	Analyzed the data	Formal analysis	YES
5719219	29175905	S.D.M.J.	4	Data acquisition was performed by|data analysis by	Data acquisition was performed by	Performed the experiments	Investigation	YES
5719219	29175905	S.D.M.J.	4	Data acquisition was performed by|data analysis by	data analysis by	Analyzed the data	Formal analysis	YES
5719219	29175905	S.W.T.P.	4	Data acquisition was performed by|data analysis by|data interpretation by|The manuscript was written by	Data acquisition was performed by	Performed the experiments	Investigation	YES
5719219	29175905	S.W.T.P.	4	Data acquisition was performed by|data analysis by|data interpretation by|The manuscript was written by	data analysis by	Analyzed the data	Formal analysis	YES
5719219	29175905	S.W.T.P.	4	Data acquisition was performed by|data analysis by|data interpretation by|The manuscript was written by	data interpretation by	Analyzed the data	Formal analysis	YES
5719219	29175905	S.W.T.P.	4	Data acquisition was performed by|data analysis by|data interpretation by|The manuscript was written by	The manuscript was written by	Wrote the paper	Writing - Original Draft	YES
1819556	17375200	AB	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1819556	17375200	AB	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1819556	17375200	BL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1819556	17375200	CT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1819556	17375200	CT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1819556	17375200	CT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1819556	17375200	DP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1819556	17375200	EL	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1819556	17375200	KL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1819556	17375200	KL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1819556	17375200	KL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1819556	17375200	RK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1819556	17375200	RK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1819556	17375200	SC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1819556	17375200	SC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1819556	17375200	WH	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
6432111	30907508	All authors	2	contributed to the final manuscript	contributed to the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6432111	30907508	CJ	2	drafted the manuscript with inputs from all authors	drafted the manuscript with inputs from all authors	Wrote the paper	Writing - Original Draft	YES
6432111	30907508	ELC	2	drafted the manuscript with inputs from all authors	drafted the manuscript with inputs from all authors	Wrote the paper	Writing - Original Draft	YES
6432111	30907508	KH	2	led the star implementation	led the star implementation	Performed the experiments	Investigation	YES
6432111	30907508	MK	2	drafted the manuscript with inputs from all authors	drafted the manuscript with inputs from all authors	Wrote the paper	Writing - Original Draft	YES
6432111	30907508	MT	2	led the qualitative research network in star and contributed to the qualitative analysis	led the qualitative research network in star and contributed to the qualitative analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6432111	30907508	ND	2	drafted the manuscript with inputs from all authors|developed the st-impacts study	drafted the manuscript with inputs from all authors	Wrote the paper	Writing - Original Draft	YES
6432111	30907508	ND	2	drafted the manuscript with inputs from all authors|developed the st-impacts study	developed the st-impacts study	-	-	NO
6432111	30907508	RC	2	led the star implementation	led the star implementation	Performed the experiments	Investigation	YES
6432111	30907508	WL	2	developed the st-impacts study	developed the st-impacts study	-	-	NO
4411087	25915759	BL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411087	25915759	BL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411087	25915759	BL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411087	25915759	BL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411087	25915759	CXZ	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411087	25915759	CXZ	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411087	25915759	FYL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411087	25915759	LW	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4411087	25915759	LW	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4411087	25915759	MSL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411087	25915759	SCH	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411087	25915759	SCH	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411087	25915759	XFM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5663694	29163566	AA	2	conceived the designed research and interpreted the results	conceived the designed research and interpreted the results	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
5663694	29163566	AV	2	developed the mrm methods and performed the analyses	developed the mrm methods and performed the analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5663694	29163566	AVQ	2	interpreted the mass spectrometry data	interpreted the mass spectrometry data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5663694	29163566	All authors	2	contributed to drafting and/or critical revision of the work and approved the manuscript	contributed to drafting and/or critical revision of the work and approved the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5663694	29163566	EM	2	interpreted the mass spectrometry data	interpreted the mass spectrometry data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5663694	29163566	JB	2	performed the chemometrics analysis	performed the chemometrics analysis	Performed the experiments	Investigation	YES
5663694	29163566	JP	2	conceived the designed research and interpreted the results	conceived the designed research and interpreted the results	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
5663694	29163566	LL	2	conceived the designed research and interpreted the results	conceived the designed research and interpreted the results	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
5663694	29163566	LP	2	developed the mrm methods and performed the analyses	developed the mrm methods and performed the analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5663694	29163566	MR	2	developed and applied the extraction protocols	developed and applied the extraction protocols	Conceived and designed the experiments	Methodology	YES
5663694	29163566	NS	2	supervised the metabolomics analysis|conceived the designed research and interpreted the results	supervised the metabolomics analysis	-	Supervision	YES
5663694	29163566	NS	2	supervised the metabolomics analysis|conceived the designed research and interpreted the results	conceived the designed research and interpreted the results	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
5663694	29163566	NT	2	performed the chemometrics analysis|conceived the designed research and interpreted the results	performed the chemometrics analysis	Performed the experiments	Investigation	YES
5663694	29163566	NT	2	performed the chemometrics analysis|conceived the designed research and interpreted the results	conceived the designed research and interpreted the results	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
5663694	29163566	VC	2	conceived the designed research and interpreted the results	conceived the designed research and interpreted the results	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
1819558	17375193	AS	PLoS5	Contributed reagents/materials/analysis tools|Helped write the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1819558	17375193	AS	PLoS5	Contributed reagents/materials/analysis tools|Helped write the paper	Helped write the paper	Wrote the paper	Writing - Original Draft	YES
1819558	17375193	BR	PLoS5	Helped develop the experimental design, analyze the data and write the paper	Helped develop the experimental design, analyze the data and write the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
1819558	17375193	IM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1819558	17375193	IM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1819558	17375193	IM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1819558	17375193	IM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1819558	17375193	IM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1819558	17375193	OS	PLoS5	Contributed reagents/materials/analysis tools|Helped analyze the data and write the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1819558	17375193	OS	PLoS5	Contributed reagents/materials/analysis tools|Helped analyze the data and write the paper	Helped analyze the data and write the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
1819558	17375193	SE	PLoS5	Contributed reagents/materials/analysis tools|Helped analyze the data and write the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1819558	17375193	SE	PLoS5	Contributed reagents/materials/analysis tools|Helped analyze the data and write the paper	Helped analyze the data and write the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
1819558	17375193	TB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1819558	17375193	TB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1819558	17375193	TB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1819558	17375193	TB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1819558	17375193	TB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5499013	28683832	AMM	2	performed dna extractions, assembly and annotation of plastid genomes, sequence alignments, comparative analysis of plastid genomes, phylogenetic analysis, estimation of times of divergence, and drafted the manuscript	performed dna extractions, assembly and annotation of plastid genomes, sequence alignments, comparative analysis of plastid genomes, phylogenetic analysis, estimation of times of divergence, and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Formal analysis|Investigation|Writing - Original Draft	YES
5499013	28683832	All authors	2	read and contributed written sections of the final manuscript	read and contributed written sections of the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5499013	28683832	MEF	2	allocated resources, designed the experiments, obtained the sequencing data, supervised the study and drafted the manuscript	allocated resources, designed the experiments, obtained the sequencing data, supervised the study and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Methodology|Resources|Supervision|Writing - Original Draft	YES
5499013	28683832	MPF	2	performed dna extractions, assembly and annotation of plastid genomes, sequence alignments, comparative analysis of plastid genomes, phylogenetic analysis, estimation of times of divergence, and drafted the manuscript	performed dna extractions, assembly and annotation of plastid genomes, sequence alignments, comparative analysis of plastid genomes, phylogenetic analysis, estimation of times of divergence, and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Formal analysis|Investigation|Writing - Original Draft	YES
4564624	26413522	All authors	2	have read and approved the final paper	have read and approved the final paper	-	-	NO
4564624	26413522	Bintou Sanno-Duanda	2	contributed to analysis, interpretation of data, and paper drafting	contributed to analysis, interpretation of data, and paper drafting	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
4564624	26413522	Chi-Ming Hung	2	carried out experiments	carried out experiments	Performed the experiments	Investigation	YES
4564624	26413522	Hung-Shiang Cheng	2	carried out experiments	carried out experiments	Performed the experiments	Investigation	YES
4564624	26413522	Kuan-Tsou Lin	2	performed data analysis and experiments	performed data analysis and experiments	Analyzed the data	Formal analysis	YES
4564624	26413522	Kuei-Hsiang Lin	2	performed conception and overall coordination of study and paper revision|equal contributed to this work	performed conception and overall coordination of study and paper revision	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Project administration|Writing - Review & Editing	YES
4564624	26413522	Kuei-Hsiang Lin	2	performed conception and overall coordination of study and paper revision|equal contributed to this work	equal contributed to this work	-	-	NO
4564624	26413522	Mei-Hua Tsai	2	contributed to analysis, interpretation of data, and paper drafting|equal contributed to this work	contributed to analysis, interpretation of data, and paper drafting	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
4564624	26413522	Mei-Hua Tsai	2	contributed to analysis, interpretation of data, and paper drafting|equal contributed to this work	equal contributed to this work	-	-	NO
4564624	26413522	Ming-Hui Yang	2	contributed to interpretation of data	contributed to interpretation of data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
4564624	26413522	Pei-Yu Chu	2	contributed to study design and paper revision	contributed to study design and paper revision	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
4564624	26413522	Shyng-Shiou Yuan	2	contributed to interpretation of data	contributed to interpretation of data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
4564624	26413522	Yu-Chang Tyan	2	contributed to interpretation of data	contributed to interpretation of data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5784097	29311205	A.K.	2	carried out the numerical modelling, data analysis and drafted the manuscript	carried out the numerical modelling, data analysis and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5784097	29311205	J.G.	2	conducted the experiments	conducted the experiments	Performed the experiments	Investigation	YES
5784097	29311205	K.P.	2	performed data analysis and drafted the manuscript	performed data analysis and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6432491	30907514	CJ	PLoS52	wrote the concise communication	wrote the concise communication	Wrote the paper	Writing - Original Draft	YES
6432491	30907514	CW	PLoS52	performed the experiments|wrote the concise communication	performed the experiments	Performed the experiments	Investigation	YES
6432491	30907514	CW	PLoS52	performed the experiments|wrote the concise communication	wrote the concise communication	Wrote the paper	Writing - Original Draft	YES
6432491	30907514	EA	PLoS52	performed the experiments|wrote the concise communication	performed the experiments	Performed the experiments	Investigation	YES
6432491	30907514	EA	PLoS52	performed the experiments|wrote the concise communication	wrote the concise communication	Wrote the paper	Writing - Original Draft	YES
6432491	30907514	EC	PLoS52	wrote the concise communication	wrote the concise communication	Wrote the paper	Writing - Original Draft	YES
6432491	30907514	FC	PLoS52	wrote the concise communication	wrote the concise communication	Wrote the paper	Writing - Original Draft	YES
6432491	30907514	HA	PLoS52	wrote the concise communication	wrote the concise communication	Wrote the paper	Writing - Original Draft	YES
6432491	30907514	KH	PLoS52	wrote the concise communication	wrote the concise communication	Wrote the paper	Writing - Original Draft	YES
6432491	30907514	MM	PLoS52	wrote the concise communication	wrote the concise communication	Wrote the paper	Writing - Original Draft	YES
6432491	30907514	MT	PLoS52	formulated and designed the experiments|wrote the concise communication	formulated and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6432491	30907514	MT	PLoS52	formulated and designed the experiments|wrote the concise communication	wrote the concise communication	Wrote the paper	Writing - Original Draft	YES
6432491	30907514	PM	PLoS52	analysed the data|wrote the concise communication	analysed the data	Analyzed the data	Formal analysis	YES
6432491	30907514	PM	PLoS52	analysed the data|wrote the concise communication	wrote the concise communication	Wrote the paper	Writing - Original Draft	YES
6432491	30907514	RD	PLoS52	formulated and designed the experiments|performed the experiments|analysed the data|wrote the concise communication	formulated and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6432491	30907514	RD	PLoS52	formulated and designed the experiments|performed the experiments|analysed the data|wrote the concise communication	performed the experiments	Performed the experiments	Investigation	YES
6432491	30907514	RD	PLoS52	formulated and designed the experiments|performed the experiments|analysed the data|wrote the concise communication	analysed the data	Analyzed the data	Formal analysis	YES
6432491	30907514	RD	PLoS52	formulated and designed the experiments|performed the experiments|analysed the data|wrote the concise communication	wrote the concise communication	Wrote the paper	Writing - Original Draft	YES
6432491	30907514	TE	PLoS52	performed the experiments|wrote the concise communication	performed the experiments	Performed the experiments	Investigation	YES
6432491	30907514	TE	PLoS52	performed the experiments|wrote the concise communication	wrote the concise communication	Wrote the paper	Writing - Original Draft	YES
6432491	30907514	VW	PLoS52	formulated and designed the experiments|performed the experiments|analysed the data|wrote the concise communication	formulated and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6432491	30907514	VW	PLoS52	formulated and designed the experiments|performed the experiments|analysed the data|wrote the concise communication	performed the experiments	Performed the experiments	Investigation	YES
6432491	30907514	VW	PLoS52	formulated and designed the experiments|performed the experiments|analysed the data|wrote the concise communication	analysed the data	Analyzed the data	Formal analysis	YES
6432491	30907514	VW	PLoS52	formulated and designed the experiments|performed the experiments|analysed the data|wrote the concise communication	wrote the concise communication	Wrote the paper	Writing - Original Draft	YES
4411089	25915602	AA	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411089	25915602	AP	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4411089	25915602	CFZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411089	25915602	CFZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411089	25915602	CFZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411089	25915602	D. Basso	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411089	25915602	D. Basso	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411089	25915602	D. Basso	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411089	25915602	D. Bozzato	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411089	25915602	EG	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411089	25915602	EG	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411089	25915602	ER	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411089	25915602	ER	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4411089	25915602	FN	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411089	25915602	FN	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411089	25915602	FN	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411089	25915602	GG	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411089	25915602	M. Pelloso	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4411089	25915602	M. Pelloso	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411089	25915602	M. Pescarin	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411089	25915602	M. Plebani	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411089	25915602	MC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4411089	25915602	MC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411089	25915602	SA	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411089	25915602	SM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5663695	29163567	AE	2	manuscript writing was completed by all authors	manuscript writing was completed by all authors	Wrote the paper	Writing - Original Draft	YES
5663695	29163567	KM	2	manuscript writing was completed by all authors	manuscript writing was completed by all authors	Wrote the paper	Writing - Original Draft	YES
5663695	29163567	KS	2	manuscript writing was completed by all authors	manuscript writing was completed by all authors	Wrote the paper	Writing - Original Draft	YES
5805918	29431682	E.J.D.	2	contributed to the acquisition and analysis of data	contributed to the acquisition and analysis of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5805918	29431682	J.C.H.	2	made significant contributions to the conception and design of this study	made significant contributions to the conception and design of this study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5805918	29431682	R.L.J.	2	made significant contributions to the conception and design of this study, drafting and revising the article and approving the article for publication	made significant contributions to the conception and design of this study, drafting and revising the article and approving the article for publication	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5805918	29431682	Y.C.	2	contributed to the acquisition and analysis of data	contributed to the acquisition and analysis of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
1819560	17375196	AC	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1819560	17375196	IG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1819560	17375196	IG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1819560	17375196	IG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1819560	17375196	IG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1819560	17375196	MP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1819560	17375196	SD	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1819560	17375196	SR	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1819560	17375196	SR	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1819560	17375196	SR	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6433601	30912306	All authors	2	critically reviewed the manuscript, suggested revisions and editorial changes, and approved the final version	critically reviewed the manuscript, suggested revisions and editorial changes, and approved the final version	Wrote the paper	Writing - Review & Editing	YES
6433601	30912306	EJ	2	drafted the initial manuscript	drafted the initial manuscript	Wrote the paper	Writing - Original Draft	YES
6433601	30912306	VW	2	drafted the initial manuscript	drafted the initial manuscript	Wrote the paper	Writing - Original Draft	YES
5663696	29163582	AR	2	conceived the study and wrote the paper|implemented the algorithms described and prepared results	conceived the study and wrote the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5663696	29163582	AR	2	conceived the study and wrote the paper|implemented the algorithms described and prepared results	implemented the algorithms described and prepared results	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5663696	29163582	BA	2	conceived the study and wrote the paper|collected and processed data	conceived the study and wrote the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5663696	29163582	BA	2	conceived the study and wrote the paper|collected and processed data	collected and processed data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5663696	29163582	DH	2	conceived the study and wrote the paper	conceived the study and wrote the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5663696	29163582	JL	2	conceived the study and wrote the paper|collected and processed data	conceived the study and wrote the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5663696	29163582	JL	2	conceived the study and wrote the paper|collected and processed data	collected and processed data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5663696	29163582	KB	2	conceived the study and wrote the paper|collected and processed data	conceived the study and wrote the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5663696	29163582	KB	2	conceived the study and wrote the paper|collected and processed data	collected and processed data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5663696	29163582	PM	2	implemented the algorithms described and prepared results	implemented the algorithms described and prepared results	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
4411090	25915038	AC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411090	25915038	JMA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411090	25915038	JMA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411090	25915038	JMA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411090	25915038	JMA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411090	25915038	JRM	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4411090	25915038	KBR	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411090	25915038	KBR	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411090	25915038	KBR	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411090	25915038	MC	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411090	25915038	MC	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411090	25915038	TE	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411090	25915038	VY	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411090	25915038	YZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5499015	28679357	DM	2	performed data analysis involving promoter elements and taxonomy|contributed to data discussions, manuscript writing and assembly	performed data analysis involving promoter elements and taxonomy	Analyzed the data	Formal analysis	YES
5499015	28679357	DM	2	performed data analysis involving promoter elements and taxonomy|contributed to data discussions, manuscript writing and assembly	contributed to data discussions, manuscript writing and assembly	Wrote the paper	Writing - Original Draft	YES
5499015	28679357	MHH	2	assisted in identifying and annotating promoter sequences	assisted in identifying and annotating promoter sequences	Performed the experiments	Investigation	YES
5499015	28679357	PS	2	performed promoter enrichment and protein domain analyses|contributed to data discussions, manuscript writing and assembly	performed promoter enrichment and protein domain analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5499015	28679357	PS	2	performed promoter enrichment and protein domain analyses|contributed to data discussions, manuscript writing and assembly	contributed to data discussions, manuscript writing and assembly	Wrote the paper	Writing - Original Draft	YES
5499015	28679357	RGU	2	conceived the study, performed hmm, subcellular localization and phylogenetic tree analyses|contributed to data discussions, manuscript writing and assembly	conceived the study, performed hmm, subcellular localization and phylogenetic tree analyses	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation	YES
5499015	28679357	RGU	2	conceived the study, performed hmm, subcellular localization and phylogenetic tree analyses|contributed to data discussions, manuscript writing and assembly	contributed to data discussions, manuscript writing and assembly	Wrote the paper	Writing - Original Draft	YES
5499015	28679357	WG	2	contributed to data discussions, manuscript writing and assembly	contributed to data discussions, manuscript writing and assembly	Wrote the paper	Writing - Original Draft	YES
4411091	25915398	ACA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411091	25915398	ACA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411091	25915398	ACA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411091	25915398	ACA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411091	25915398	ACA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411091	25915398	BRB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411091	25915398	BRB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411091	25915398	BRB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411091	25915398	BRB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411091	25915398	HR	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411091	25915398	HR	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411091	25915398	MNK	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411091	25915398	MNK	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411091	25915398	MNK	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1819562	17375195	DR	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1819562	17375195	DW	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Manuscript	Performed the experiments	Performed the experiments	Investigation	YES
1819562	17375195	DW	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
1819562	17375195	DW	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1819562	17375195	DW	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1819562	17375195	DW	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Manuscript	Manuscript	-	-	NO
1819562	17375195	EC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Manuscript	Performed the experiments	Performed the experiments	Investigation	YES
1819562	17375195	EC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1819562	17375195	EC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Manuscript	Manuscript	-	-	NO
1819562	17375195	JH	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1819562	17375195	JL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1819562	17375195	JR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1819562	17375195	JR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1819562	17375195	JR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1819562	17375195	JR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1819562	17375195	JR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1819562	17375195	LL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1819562	17375195	LR	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1819562	17375195	ME	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1819562	17375195	MM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1819562	17375195	MR	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1819562	17375195	MR	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1819562	17375195	MR	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1819562	17375195	PM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Manuscript	Performed the experiments	Performed the experiments	Investigation	YES
1819562	17375195	PM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
1819562	17375195	PM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1819562	17375195	PM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Manuscript	Manuscript	-	-	NO
1819562	17375195	TC	PLoS5	Contributed reagents/materials/analysis tools|Manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1819562	17375195	TC	PLoS5	Contributed reagents/materials/analysis tools|Manuscript	Manuscript	-	-	NO
1819562	17375195	TW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1819562	17375195	TW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1819562	17375195	TW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1819562	17375195	TW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1819562	17375195	TW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1819562	17375195	WF	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1819562	17375195	WF	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1819562	17375195	WF	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6436499	30916897	AW	2	were involved in the data collection	were involved in the data collection	Performed the experiments	Investigation	YES
6436499	30916897	All authors	2	contributed to the writing and revision of the manuscript	contributed to the writing and revision of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6436499	30916897	GH	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
6436499	30916897	JD	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
6436499	30916897	JK	2	were involved in the data collection	were involved in the data collection	Performed the experiments	Investigation	YES
6436499	30916897	JMG	2	designed the study|conducted the analyses	designed the study	Conceived and designed the experiments	Methodology	YES
6436499	30916897	JMG	2	designed the study|conducted the analyses	conducted the analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6436499	30916897	LM	2	were involved in the data collection	were involved in the data collection	Performed the experiments	Investigation	YES
6436499	30916897	MS	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
6436499	30916897	PG	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
6436499	30916897	TB	2	were involved in the data collection|designed the study	were involved in the data collection	Performed the experiments	Investigation	YES
6436499	30916897	TB	2	were involved in the data collection|designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
6436499	30916897	TG	2	were involved in the data collection	were involved in the data collection	Performed the experiments	Investigation	YES
5663720	29163585	CR	2	performed the research	performed the research	Performed the experiments	Investigation	YES
5663720	29163585	DL	2	designed the research|performed the research|analyzed the data and wrote the article	designed the research	Conceived and designed the experiments	Methodology	YES
5663720	29163585	DL	2	designed the research|performed the research|analyzed the data and wrote the article	performed the research	Performed the experiments	Investigation	YES
5663720	29163585	DL	2	designed the research|performed the research|analyzed the data and wrote the article	analyzed the data and wrote the article	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5663720	29163585	OP	2	designed the research|analyzed the data and wrote the article	designed the research	Conceived and designed the experiments	Methodology	YES
5663720	29163585	OP	2	designed the research|analyzed the data and wrote the article	analyzed the data and wrote the article	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5663720	29163585	SK	2	performed the research	performed the research	Performed the experiments	Investigation	YES
5663720	29163585	YK	2	performed the research	performed the research	Performed the experiments	Investigation	YES
5829175	29459412	C.M.	2	wrote the manuscript which was discussed among all authors	wrote the manuscript which was discussed among all authors	Wrote the paper	Writing - Original Draft	YES
5499059	28679365	AJM	2	discussed and monitored overall scientific progress of experiments	discussed and monitored overall scientific progress of experiments	-	Supervision	YES
5499059	28679365	DM	2	facilitated project management|discussed and monitored overall scientific progress of experiments	facilitated project management	-	Project administration	YES
5499059	28679365	DM	2	facilitated project management|discussed and monitored overall scientific progress of experiments	discussed and monitored overall scientific progress of experiments	-	Supervision	YES
5499059	28679365	DS	2	scripted programs for liquid handlers under the|discussed and monitored overall scientific progress of experiments	scripted programs for liquid handlers under the	-	-	NO
5499059	28679365	DS	2	scripted programs for liquid handlers under the|discussed and monitored overall scientific progress of experiments	discussed and monitored overall scientific progress of experiments	-	Supervision	YES
5499059	28679365	HK	2	technically assisted with some of the experiments	technically assisted with some of the experiments	Performed the experiments	Investigation	YES
5499059	28679365	HM	2	technically assisted with some of the experiments	technically assisted with some of the experiments	Performed the experiments	Investigation	YES
5499059	28679365	JS	2	discussed and monitored overall scientific progress of experiments	discussed and monitored overall scientific progress of experiments	-	Supervision	YES
5499059	28679365	MAM	2	conceived and oversaw the technological development projects in this study as principal investigators	conceived and oversaw the technological development projects in this study as principal investigators	Conceived and designed the experiments	Conceptualization|Funding acquisition|Supervision	YES
5499059	28679365	MB	2	discussed and monitored overall scientific progress of experiments	discussed and monitored overall scientific progress of experiments	-	Supervision	YES
5499059	28679365	MH	2	discussed and monitored overall scientific progress of experiments	discussed and monitored overall scientific progress of experiments	-	Supervision	YES
5499059	28679365	PP	2	technically assisted with some of the experiments	technically assisted with some of the experiments	Performed the experiments	Investigation	YES
5499059	28679365	PT	2	scripted programs for liquid handlers under the	scripted programs for liquid handlers under the	-	-	NO
5499059	28679365	RAH	2	conceived and oversaw the technological development projects in this study as principal investigators	conceived and oversaw the technological development projects in this study as principal investigators	Conceived and designed the experiments	Conceptualization|Funding acquisition|Supervision	YES
5499059	28679365	RAM	2	discussed and monitored overall scientific progress of experiments	discussed and monitored overall scientific progress of experiments	-	Supervision	YES
5499059	28679365	RDC	2	performed computational analysis of sequencing data under the|discussed and monitored overall scientific progress of experiments	performed computational analysis of sequencing data under the	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5499059	28679365	RDC	2	performed computational analysis of sequencing data under the|discussed and monitored overall scientific progress of experiments	discussed and monitored overall scientific progress of experiments	-	Supervision	YES
5499059	28679365	RJC	2	supervised the scripted programs for liquid handlers under the|discussed and monitored overall scientific progress of experiments	supervised the scripted programs for liquid handlers under the	-	Supervision	YES
5499059	28679365	RJC	2	supervised the scripted programs for liquid handlers under the|discussed and monitored overall scientific progress of experiments	discussed and monitored overall scientific progress of experiments	-	Supervision	YES
5499059	28679365	SB	2	performed computational analysis of sequencing data under the|discussed and monitored overall scientific progress of experiments	performed computational analysis of sequencing data under the	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5499059	28679365	SB	2	performed computational analysis of sequencing data under the|discussed and monitored overall scientific progress of experiments	discussed and monitored overall scientific progress of experiments	-	Supervision	YES
5499059	28679365	SH	2	discussed and monitored overall scientific progress of experiments	discussed and monitored overall scientific progress of experiments	-	Supervision	YES
5499059	28679365	SJJ	2	conceived and oversaw the technological development projects in this study as principal investigators	conceived and oversaw the technological development projects in this study as principal investigators	Conceived and designed the experiments	Conceptualization|Funding acquisition|Supervision	YES
5499059	28679365	TM	2	in conducting the library construction chemistry comparisons and the optimization of bead-based purifications under the	in conducting the library construction chemistry comparisons and the optimization of bead-based purifications under the	Performed the experiments	Investigation	YES
5499059	28679365	YM	2	supervised the performed computational analysis of sequencing data under the|discussed and monitored overall scientific progress of experiments	supervised the performed computational analysis of sequencing data under the	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Supervision	YES
5499059	28679365	YM	2	supervised the performed computational analysis of sequencing data under the|discussed and monitored overall scientific progress of experiments	discussed and monitored overall scientific progress of experiments	-	Supervision	YES
5499059	28679365	YZ	2	supervised the based purifications under the|discussed and monitored overall scientific progress of experiments	supervised the based purifications under the	Performed the experiments	Investigation|Supervision	YES
5499059	28679365	YZ	2	supervised the based purifications under the|discussed and monitored overall scientific progress of experiments	discussed and monitored overall scientific progress of experiments	-	Supervision	YES
6197973	30357064	MGD	2	participated in the whole process of the study design, data analysis, data collection, statistical analyses, writing and drafting the article	participated in the whole process of the study design, data analysis, data collection, statistical analyses, writing and drafting the article	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
1819563	17375197	CD	PLoS5	Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1819563	17375197	CD	PLoS5	Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1819563	17375197	DB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1819563	17375197	DB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1819563	17375197	HC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1819563	17375197	IC	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1819563	17375197	IC	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1819563	17375197	VF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1819563	17375197	VF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1819563	17375197	VF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1819563	17375197	VF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1819563	17375197	VF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411092	25915045	AFL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411092	25915045	ASS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411092	25915045	ASS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411092	25915045	ASS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411092	25915045	IEG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4411092	25915045	IEG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411092	25915045	JCA	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411092	25915045	JI	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411092	25915045	LDM	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4411092	25915045	LDM	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4411092	25915045	LFR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411092	25915045	LFR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411092	25915045	LFR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411092	25915045	RHP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4411092	25915045	RHP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411092	25915045	RMS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411092	25915045	RMS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411092	25915045	RMS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411092	25915045	RMS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411092	25915045	SMP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5663930	29163568	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5663930	29163568	The authors	2	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	Performed the experiments	Investigation	YES
5663930	29163568	WC	2	provided advice and edited the manuscript	provided advice and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5663930	29163568	XL	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5663930	29163568	YT	2	provided advice and edited the manuscript	provided advice and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5663930	29163568	YZ	2	provided advice and edited the manuscript	provided advice and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5663930	29163568	ZL	2	provided advice and edited the manuscript	provided advice and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5829177	29459414	S.U.	2	edited and improved by all co-authors	edited and improved by all co-authors	Wrote the paper	Writing - Review & Editing	YES
6439318	30924281	AA	2	were involved in data collection	were involved in data collection	Performed the experiments	Investigation	YES
6439318	30924281	AJ	2	were involved in data analysis|were involved in data interpretation and presentation of the results	were involved in data analysis	Analyzed the data	Formal analysis	YES
6439318	30924281	AJ	2	were involved in data analysis|were involved in data interpretation and presentation of the results	were involved in data interpretation and presentation of the results	Analyzed the data	Formal analysis	YES
6439318	30924281	AK	2	were involved in data collection	were involved in data collection	Performed the experiments	Investigation	YES
6439318	30924281	AW	2	were involved in data collection|were involved in data interpretation and presentation of the results	were involved in data collection	Performed the experiments	Investigation	YES
6439318	30924281	AW	2	were involved in data collection|were involved in data interpretation and presentation of the results	were involved in data interpretation and presentation of the results	Analyzed the data	Formal analysis	YES
6439318	30924281	BLHS	2	were involved in data collection	were involved in data collection	Performed the experiments	Investigation	YES
6439318	30924281	CDD	2	were involved in data collection	were involved in data collection	Performed the experiments	Investigation	YES
6439318	30924281	FJZ	2	were involved in data collection	were involved in data collection	Performed the experiments	Investigation	YES
6439318	30924281	JM	2	were involved in data analysis|were involved in data interpretation and presentation of the results	were involved in data analysis	Analyzed the data	Formal analysis	YES
6439318	30924281	JM	2	were involved in data analysis|were involved in data interpretation and presentation of the results	were involved in data interpretation and presentation of the results	Analyzed the data	Formal analysis	YES
6439318	30924281	JT	2	were involved in data collection	were involved in data collection	Performed the experiments	Investigation	YES
6439318	30924281	JYC	2	were involved in data collection	were involved in data collection	Performed the experiments	Investigation	YES
6439318	30924281	KJ	2	were involved in data collection|were involved in data interpretation and presentation of the results	were involved in data collection	Performed the experiments	Investigation	YES
6439318	30924281	KJ	2	were involved in data collection|were involved in data interpretation and presentation of the results	were involved in data interpretation and presentation of the results	Analyzed the data	Formal analysis	YES
6439318	30924281	KVN	2	were involved in data collection	were involved in data collection	Performed the experiments	Investigation	YES
6439318	30924281	MKP	2	were involved in data collection|were involved in data interpretation and presentation of the results	were involved in data collection	Performed the experiments	Investigation	YES
6439318	30924281	MKP	2	were involved in data collection|were involved in data interpretation and presentation of the results	were involved in data interpretation and presentation of the results	Analyzed the data	Formal analysis	YES
6439318	30924281	MPL	2	were involved in data collection	were involved in data collection	Performed the experiments	Investigation	YES
6439318	30924281	NK	2	were involved in data collection	were involved in data collection	Performed the experiments	Investigation	YES
6439318	30924281	OTN	2	were involved in data collection	were involved in data collection	Performed the experiments	Investigation	YES
6439318	30924281	PSL	2	were involved in data collection	were involved in data collection	Performed the experiments	Investigation	YES
6439318	30924281	RC	2	were involved in data collection|were involved in data interpretation and presentation of the results	were involved in data collection	Performed the experiments	Investigation	YES
6439318	30924281	RC	2	were involved in data collection|were involved in data interpretation and presentation of the results	were involved in data interpretation and presentation of the results	Analyzed the data	Formal analysis	YES
6439318	30924281	SK	2	were involved in data collection|were involved in data collection	were involved in data collection	Performed the experiments	Investigation	YES
6439318	30924281	SK	2	were involved in data collection|were involved in data collection	were involved in data collection	Performed the experiments	Investigation	YES
6439318	30924281	SWWK	2	were involved in data collection|were involved in data analysis|were involved in data interpretation and presentation of the results	were involved in data collection	Performed the experiments	Investigation	YES
6439318	30924281	SWWK	2	were involved in data collection|were involved in data analysis|were involved in data interpretation and presentation of the results	were involved in data analysis	Analyzed the data	Formal analysis	YES
6439318	30924281	SWWK	2	were involved in data collection|were involved in data analysis|were involved in data interpretation and presentation of the results	were involved in data interpretation and presentation of the results	Analyzed the data	Formal analysis	YES
6439318	30924281	TPM	2	were involved in data collection	were involved in data collection	Performed the experiments	Investigation	YES
6439318	30924281	WR	2	were involved in data collection	were involved in data collection	Performed the experiments	Investigation	YES
6439318	30924281	WWW	2	were involved in data collection|were involved in data analysis|were involved in data interpretation and presentation of the results	were involved in data collection	Performed the experiments	Investigation	YES
6439318	30924281	WWW	2	were involved in data collection|were involved in data analysis|were involved in data interpretation and presentation of the results	were involved in data analysis	Analyzed the data	Formal analysis	YES
6439318	30924281	WWW	2	were involved in data collection|were involved in data analysis|were involved in data interpretation and presentation of the results	were involved in data interpretation and presentation of the results	Analyzed the data	Formal analysis	YES
1819564	17375198	AC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1819564	17375198	AS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1819564	17375198	AT	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1819564	17375198	AT	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1819564	17375198	AT	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1819564	17375198	CL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1819564	17375198	CL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1819564	17375198	CO	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1819564	17375198	CO	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1819564	17375198	JC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1819564	17375198	JC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1819564	17375198	JC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1819564	17375198	RD	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1819564	17375198	XP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1819564	17375198	XP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5501078	28683819	CR	3	Study concept and design|Analysis and interpretation of data|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content|Obtained funding|Administrative, technical, or material support|Study supervision	Study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5501078	28683819	CR	3	Study concept and design|Analysis and interpretation of data|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content|Obtained funding|Administrative, technical, or material support|Study supervision	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
5501078	28683819	CR	3	Study concept and design|Analysis and interpretation of data|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content|Obtained funding|Administrative, technical, or material support|Study supervision	Drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
5501078	28683819	CR	3	Study concept and design|Analysis and interpretation of data|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content|Obtained funding|Administrative, technical, or material support|Study supervision	Critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5501078	28683819	CR	3	Study concept and design|Analysis and interpretation of data|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content|Obtained funding|Administrative, technical, or material support|Study supervision	Obtained funding	-	Funding acquisition	YES
5501078	28683819	CR	3	Study concept and design|Analysis and interpretation of data|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content|Obtained funding|Administrative, technical, or material support|Study supervision	Administrative, technical, or material support	Performed the experiments	Investigation|Project administration	YES
5501078	28683819	CR	3	Study concept and design|Analysis and interpretation of data|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content|Obtained funding|Administrative, technical, or material support|Study supervision	Study supervision	-	Supervision	YES
5501078	28683819	DE	3	Acquisition of data|Analysis and interpretation of data|Drafting of the manuscript|Statistical analysis	Acquisition of data	Performed the experiments	Investigation	YES
5501078	28683819	DE	3	Acquisition of data|Analysis and interpretation of data|Drafting of the manuscript|Statistical analysis	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
5501078	28683819	DE	3	Acquisition of data|Analysis and interpretation of data|Drafting of the manuscript|Statistical analysis	Drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
5501078	28683819	DE	3	Acquisition of data|Analysis and interpretation of data|Drafting of the manuscript|Statistical analysis	Statistical analysis	Analyzed the data	Formal analysis	YES
5501078	28683819	JH	3	Acquisition of data|Analysis and interpretation of data|Administrative, technical, or material support	Acquisition of data	Performed the experiments	Investigation	YES
5501078	28683819	JH	3	Acquisition of data|Analysis and interpretation of data|Administrative, technical, or material support	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
5501078	28683819	JH	3	Acquisition of data|Analysis and interpretation of data|Administrative, technical, or material support	Administrative, technical, or material support	Performed the experiments	Investigation|Project administration	YES
5501078	28683819	NH	3	Acquisition of data	Acquisition of data	Performed the experiments	Investigation	YES
5501078	28683819	PR	3	Study concept and design|Analysis and interpretation of data|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content|Statistical analysis|Obtained funding|Administrative, technical, or material support|Study supervision	Study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5501078	28683819	PR	3	Study concept and design|Analysis and interpretation of data|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content|Statistical analysis|Obtained funding|Administrative, technical, or material support|Study supervision	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
5501078	28683819	PR	3	Study concept and design|Analysis and interpretation of data|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content|Statistical analysis|Obtained funding|Administrative, technical, or material support|Study supervision	Drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
5501078	28683819	PR	3	Study concept and design|Analysis and interpretation of data|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content|Statistical analysis|Obtained funding|Administrative, technical, or material support|Study supervision	Critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5501078	28683819	PR	3	Study concept and design|Analysis and interpretation of data|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content|Statistical analysis|Obtained funding|Administrative, technical, or material support|Study supervision	Statistical analysis	Analyzed the data	Formal analysis	YES
5501078	28683819	PR	3	Study concept and design|Analysis and interpretation of data|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content|Statistical analysis|Obtained funding|Administrative, technical, or material support|Study supervision	Obtained funding	-	Funding acquisition	YES
5501078	28683819	PR	3	Study concept and design|Analysis and interpretation of data|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content|Statistical analysis|Obtained funding|Administrative, technical, or material support|Study supervision	Administrative, technical, or material support	Performed the experiments	Investigation|Project administration	YES
5501078	28683819	PR	3	Study concept and design|Analysis and interpretation of data|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content|Statistical analysis|Obtained funding|Administrative, technical, or material support|Study supervision	Study supervision	-	Supervision	YES
5501078	28683819	SK	3	Acquisition of data|Administrative, technical, or material support	Acquisition of data	Performed the experiments	Investigation	YES
5501078	28683819	SK	3	Acquisition of data|Administrative, technical, or material support	Administrative, technical, or material support	Performed the experiments	Investigation|Project administration	YES
5501078	28683819	SS	3	Acquisition of data|Drafting of the manuscript	Acquisition of data	Performed the experiments	Investigation	YES
5501078	28683819	SS	3	Acquisition of data|Drafting of the manuscript	Drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
5501078	28683819	VW	3	Acquisition of data	Acquisition of data	Performed the experiments	Investigation	YES
1820848	17375201	AJ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1820848	17375201	CC	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1820848	17375201	CC	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1820848	17375201	CW	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1820848	17375201	CW	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1820848	17375201	CW	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1820848	17375201	DL	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1820848	17375201	DL	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1820848	17375201	DW	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1820848	17375201	DW	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1820848	17375201	FZ	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1820848	17375201	FZ	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1820848	17375201	GG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1820848	17375201	GG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1820848	17375201	GG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1820848	17375201	HS	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1820848	17375201	HY	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1820848	17375201	JG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1820848	17375201	JT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1820848	17375201	JT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1820848	17375201	JT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1820848	17375201	JW	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Analyzed the data|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1820848	17375201	JW	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Analyzed the data|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1820848	17375201	JW	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Analyzed the data|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1820848	17375201	JW	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Analyzed the data|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1820848	17375201	JY	PLoS5	Conceived and designed the experiments|Analyzed the data|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1820848	17375201	JY	PLoS5	Conceived and designed the experiments|Analyzed the data|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1820848	17375201	JY	PLoS5	Conceived and designed the experiments|Analyzed the data|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1820848	17375201	JY	PLoS5	Conceived and designed the experiments|Analyzed the data|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1820848	17375201	ML	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1820848	17375201	ML	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1820848	17375201	RY	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1820848	17375201	RY	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1820848	17375201	RY	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1820848	17375201	TF	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1820848	17375201	WD	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1820848	17375201	WD	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1820848	17375201	WJ	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1820848	17375201	WS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1820848	17375201	XP	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1820848	17375201	XP	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1820848	17375201	XW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1820848	17375201	XW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1820848	17375201	XZ	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1820848	17375201	YD	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1820848	17375201	YF	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1820848	17375201	YF	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1820848	17375201	YF	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1820848	17375201	YJ	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1820848	17375201	YS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1820848	17375201	ZG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411093	25915516	CAP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411093	25915516	CAP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4411093	25915516	CAP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4411093	25915516	CAP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411093	25915516	LZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411093	25915516	LZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411093	25915516	LZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411093	25915516	LZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411093	25915516	SJC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411093	25915516	SJC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411093	25915516	SJC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411093	25915516	SJC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411093	25915516	SJC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411093	25915516	VvS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411093	25915516	VvS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411093	25915516	VvS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411093	25915516	VvS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5663994	29163559	DA	2	performed the data analysis including genome-wide association scan and related analyses|wrote the manuscript	performed the data analysis including genome-wide association scan and related analyses	Analyzed the data	Formal analysis	YES
5663994	29163559	DA	2	performed the data analysis including genome-wide association scan and related analyses|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5663994	29163559	KE	2	participated in calcium concentration measurements	participated in calcium concentration measurements	Performed the experiments	Investigation	YES
5663994	29163559	KP	2	designed the experiment	designed the experiment	Conceived and designed the experiments	Methodology	YES
5663994	29163559	MR	2	designed the experiment|conceived the idea and participated in the interpretation of results|wrote the manuscript	designed the experiment	Conceived and designed the experiments	Methodology	YES
5663994	29163559	MR	2	designed the experiment|conceived the idea and participated in the interpretation of results|wrote the manuscript	conceived the idea and participated in the interpretation of results	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
5663994	29163559	MR	2	designed the experiment|conceived the idea and participated in the interpretation of results|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5663994	29163559	NvW	2	participated in calcium concentration measurements	participated in calcium concentration measurements	Performed the experiments	Investigation	YES
6441924	30932364	AK	2	interpreted the data|contributed to subsequent revisions	interpreted the data	Analyzed the data	Formal analysis	YES
6441924	30932364	AK	2	interpreted the data|contributed to subsequent revisions	contributed to subsequent revisions	Wrote the paper	Writing - Review & Editing	YES
6441924	30932364	AT	2	conducted or contributed to data analysis|contributed to subsequent revisions	conducted or contributed to data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6441924	30932364	AT	2	conducted or contributed to data analysis|contributed to subsequent revisions	contributed to subsequent revisions	Wrote the paper	Writing - Review & Editing	YES
6441924	30932364	BC	2	designed the study|interpreted the data|contributed to subsequent revisions	designed the study	Conceived and designed the experiments	Methodology	YES
6441924	30932364	BC	2	designed the study|interpreted the data|contributed to subsequent revisions	interpreted the data	Analyzed the data	Formal analysis	YES
6441924	30932364	BC	2	designed the study|interpreted the data|contributed to subsequent revisions	contributed to subsequent revisions	Wrote the paper	Writing - Review & Editing	YES
6441924	30932364	CA	2	supervised and collected the study data|interpreted the data	supervised and collected the study data	Performed the experiments	Investigation|Supervision	YES
6441924	30932364	CA	2	supervised and collected the study data|interpreted the data	interpreted the data	Analyzed the data	Formal analysis	YES
6441924	30932364	IM	2	supervised and collected the study data	supervised and collected the study data	Performed the experiments	Investigation|Supervision	YES
6441924	30932364	LO	2	supervised and collected the study data|interpreted the data	supervised and collected the study data	Performed the experiments	Investigation|Supervision	YES
6441924	30932364	LO	2	supervised and collected the study data|interpreted the data	interpreted the data	Analyzed the data	Formal analysis	YES
6441924	30932364	NM	2	supervised and collected the study data|contributed to subsequent revisions	supervised and collected the study data	Performed the experiments	Investigation|Supervision	YES
6441924	30932364	NM	2	supervised and collected the study data|contributed to subsequent revisions	contributed to subsequent revisions	Wrote the paper	Writing - Review & Editing	YES
6441924	30932364	RK	2	designed the study|conducted or contributed to data analysis|interpreted the data|contributed to subsequent revisions	designed the study	Conceived and designed the experiments	Methodology	YES
6441924	30932364	RK	2	designed the study|conducted or contributed to data analysis|interpreted the data|contributed to subsequent revisions	conducted or contributed to data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6441924	30932364	RK	2	designed the study|conducted or contributed to data analysis|interpreted the data|contributed to subsequent revisions	interpreted the data	Analyzed the data	Formal analysis	YES
6441924	30932364	RK	2	designed the study|conducted or contributed to data analysis|interpreted the data|contributed to subsequent revisions	contributed to subsequent revisions	Wrote the paper	Writing - Review & Editing	YES
6441924	30932364	SO	2	designed the study|supervised and collected the study data|conducted or contributed to data analysis|interpreted the data|prepared the original manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
6441924	30932364	SO	2	designed the study|supervised and collected the study data|conducted or contributed to data analysis|interpreted the data|prepared the original manuscript	supervised and collected the study data	Performed the experiments	Investigation|Supervision	YES
6441924	30932364	SO	2	designed the study|supervised and collected the study data|conducted or contributed to data analysis|interpreted the data|prepared the original manuscript	conducted or contributed to data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6441924	30932364	SO	2	designed the study|supervised and collected the study data|conducted or contributed to data analysis|interpreted the data|prepared the original manuscript	interpreted the data	Analyzed the data	Formal analysis	YES
6441924	30932364	SO	2	designed the study|supervised and collected the study data|conducted or contributed to data analysis|interpreted the data|prepared the original manuscript	prepared the original manuscript	Wrote the paper	Writing - Original Draft	YES
5501352	28687067	All authors	PLoS52	reviewed and approved the final manuscript	reviewed and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5501352	28687067	JG	PLoS52	conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5501352	28687067	JL	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5501352	28687067	WJ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5501352	28687067	WW	PLoS52	designed the study|carried out the analyses and drafted the manuscript|performed the experiments|revised the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5501352	28687067	WW	PLoS52	designed the study|carried out the analyses and drafted the manuscript|performed the experiments|revised the manuscript	carried out the analyses and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5501352	28687067	WW	PLoS52	designed the study|carried out the analyses and drafted the manuscript|performed the experiments|revised the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5501352	28687067	WW	PLoS52	designed the study|carried out the analyses and drafted the manuscript|performed the experiments|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5501352	28687067	Yan Li	PLoS52	designed the study|conceived the study|revised the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5501352	28687067	Yan Li	PLoS52	designed the study|conceived the study|revised the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5501352	28687067	Yan Li	PLoS52	designed the study|conceived the study|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5501352	28687067	Yang Li	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
6197978	30357101	AGH	2	designed the review and revised the manuscript and reviewed the summaries	designed the review and revised the manuscript and reviewed the summaries	Conceived and designed the experiments|Wrote the paper	Writing - Review & Editing	YES
6197978	30357101	AJB	2	designed the review, performed the literature review, drafted the manuscript, and made the evidence-based summaries	designed the review, performed the literature review, drafted the manuscript, and made the evidence-based summaries	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
6197978	30357101	AWM	2	revised the manuscript, reviewed the summaries, and contributed to the literature search	revised the manuscript, reviewed the summaries, and contributed to the literature search	Wrote the paper	Formal analysis|Writing - Review & Editing	YES
6197978	30357101	KT	2	designed the review and revised the manuscript and reviewed the summaries	designed the review and revised the manuscript and reviewed the summaries	Conceived and designed the experiments|Wrote the paper	Writing - Review & Editing	YES
6197978	30357101	SZA	2	revised the manuscript, reviewed the summaries, and contributed to the literature search	revised the manuscript, reviewed the summaries, and contributed to the literature search	Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4411095	25915044	CFS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411095	25915044	CFS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411095	25915044	CG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411095	25915044	CG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4411095	25915044	CG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4411095	25915044	CS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Collection	Performed the experiments	Performed the experiments	Investigation	YES
4411095	25915044	CS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Collection	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411095	25915044	CS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Collection	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411095	25915044	CS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Collection	Collection	-	-	NO
4411095	25915044	GP	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4411095	25915044	GP	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411095	25915044	NC	PLoS5	Contributed reagents/materials/analysis tools|Collection	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411095	25915044	NC	PLoS5	Contributed reagents/materials/analysis tools|Collection	Collection	-	-	NO
4411095	25915044	RN	PLoS5	Contributed reagents/materials/analysis tools|Collection	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411095	25915044	RN	PLoS5	Contributed reagents/materials/analysis tools|Collection	Collection	-	-	NO
4411095	25915044	SP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411095	25915044	SP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411095	25915044	SP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411095	25915044	SP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1820849	17375202	AJ	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1820849	17375202	AJ	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1820849	17375202	ES	PLoS5	Conceived and designed the experiments|Performed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1820849	17375202	ES	PLoS5	Conceived and designed the experiments|Performed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1820849	17375202	ES	PLoS5	Conceived and designed the experiments|Performed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1820849	17375202	ES	PLoS5	Conceived and designed the experiments|Performed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1820849	17375202	LT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1820849	17375202	LT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1820849	17375202	LT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1820849	17375202	LT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1820849	17375202	MA	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1820849	17375202	MA	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1820849	17375202	MD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1820849	17375202	MD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1820849	17375202	MD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1820849	17375202	MD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1820849	17375202	MR	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1820849	17375202	PK	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1820849	17375202	PK	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1820849	17375202	ZN	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1820849	17375202	ZN	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1820849	17375202	ZN	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1820849	17375202	ZN	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4564631	26413552	A. C. Domingues	2	was responsible for histopathological examinations	was responsible for histopathological examinations	Performed the experiments	Investigation	YES
4564631	26413552	Alberto V. Pantoja	2	were responsible for statistical analysis	were responsible for statistical analysis	Analyzed the data	Formal analysis	YES
4564631	26413552	Alexandra R. Assad	2	were responsible for paper preparation and critical revision	were responsible for paper preparation and critical revision	Wrote the paper	Writing - Review & Editing	YES
4564631	26413552	Bruno M. Barcellos	2	were responsible for statistical analysis	were responsible for statistical analysis	Analyzed the data	Formal analysis	YES
4564631	26413552	Eduardo P. Reis	2	were responsible for acquisition of data and helped with technical procedures	were responsible for acquisition of data and helped with technical procedures	Performed the experiments	Investigation	YES
4564631	26413552	Ismar L. Cavalcanti	2	were responsible for paper preparation and critical revision	were responsible for paper preparation and critical revision	Wrote the paper	Writing - Review & Editing	YES
4564631	26413552	M. M. Castiglia	2	was responsible for study design and critical revision	was responsible for study design and critical revision	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
4564631	26413552	Renata P. Modolo	2	were responsible for acquisition of data and helped with technical procedures	were responsible for acquisition of data and helped with technical procedures	Performed the experiments	Investigation	YES
4564631	26413552	S. P. Modolo	2	was responsible for study design, data analysis, and paper preparation and supervised all phases of study	was responsible for study design, data analysis, and paper preparation and supervised all phases of study	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology|Supervision	YES
4564631	26413552	Thays D. Consolo	2	were responsible for acquisition of data and helped with technical procedures	were responsible for acquisition of data and helped with technical procedures	Performed the experiments	Investigation	YES
5501953	28687070	AM	CRediT	System integration	System integration	-	-	NO
5501953	28687070	BJ	CRediT	Material generation	Material generation	-	-	NO
5501953	28687070	CWL	CRediT	Hardware development	Hardware development	-	-	NO
5501953	28687070	HH	CRediT	Software development	Software development	Contributed reagents/materials/analysis tools	Software	YES
5501953	28687070	HS	CRediT	Data analysis	Data analysis	Analyzed the data	Formal analysis	YES
5501953	28687070	IM	CRediT	Experimental investigation	Experimental investigation	Performed the experiments	Investigation	YES
5501953	28687070	JD	CRediT	System integration	System integration	-	-	NO
5501953	28687070	JG	CRediT	Sequencing data generation	Sequencing data generation	Performed the experiments	Investigation	YES
5501953	28687070	JS	CRediT	Sequencing data generation	Sequencing data generation	Performed the experiments	Investigation	YES
5501953	28687070	JZ	CRediT	Material generation	Material generation	-	-	NO
5501953	28687070	KBP	CRediT	Material generation	Material generation	-	-	NO
5501953	28687070	KS	CRediT	Data analysis	Data analysis	Analyzed the data	Formal analysis	YES
5501953	28687070	LC	CRediT	Experimental investigation	Experimental investigation	Performed the experiments	Investigation	YES
5501953	28687070	LDG	CRediT	Data analysis|Writing	Data analysis	Analyzed the data	Formal analysis	YES
5501953	28687070	LDG	CRediT	Data analysis|Writing	Writing	Wrote the paper	-	YES
5501953	28687070	MS	CRediT	Conceptualization	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
5501953	28687070	PE	CRediT	Hardware development	Hardware development	-	-	NO
5501953	28687070	SA	CRediT	Experimental investigation	Experimental investigation	Performed the experiments	Investigation	YES
5501953	28687070	SH	CRediT	Hardware development	Hardware development	-	-	NO
5501953	28687070	SM	CRediT	Writing	Writing	Wrote the paper	-	YES
5501953	28687070	SS	CRediT	Conceptualization|Writing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
5501953	28687070	SS	CRediT	Conceptualization|Writing	Writing	Wrote the paper	-	YES
5501953	28687070	SW	CRediT	Data analysis	Data analysis	Analyzed the data	Formal analysis	YES
5501953	28687070	TS	CRediT	Hardware development	Hardware development	-	-	NO
5501953	28687070	WY	CRediT	Experimental investigation	Experimental investigation	Performed the experiments	Investigation	YES
5501953	28687070	YJC	CRediT	Experimental investigation|Writing	Experimental investigation	Performed the experiments	Investigation	YES
5501953	28687070	YJC	CRediT	Experimental investigation|Writing	Writing	Wrote the paper	-	YES
5501953	28687070	ZM	CRediT	Conceptualization|Writing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
5501953	28687070	ZM	CRediT	Conceptualization|Writing	Writing	Wrote the paper	-	YES
5897821	29610380	C.W.	2	contributed to the global coastal flood analysis	contributed to the global coastal flood analysis	-	-	NO
5897821	29610380	D.L.	2	contributed to the global coastal flood analysis	contributed to the global coastal flood analysis	-	-	NO
5897821	29610380	I.D.H.	2	conducted the climate simulations	conducted the climate simulations	Performed the experiments	Formal analysis|Investigation	YES
5897821	29610380	J.-L.M.	2	contributed on climate science and science--policy links|contributed to the global coastal flood analysis	contributed on climate science and science--policy links	-	-	NO
5897821	29610380	J.-L.M.	2	contributed on climate science and science--policy links|contributed to the global coastal flood analysis	contributed to the global coastal flood analysis	-	-	NO
5897821	29610380	J.A.G.	2	drafted the coastal ecosystems section	drafted the coastal ecosystems section	Wrote the paper	Writing - Original Draft	YES
5897821	29610380	J.H.	2	contributed to the global coastal flood analysis	contributed to the global coastal flood analysis	-	-	NO
5897821	29610380	M.S.	2	drafted the coastal ecosystems section	drafted the coastal ecosystems section	Wrote the paper	Writing - Original Draft	YES
5897821	29610380	P.G.	2	conducted the climate simulations	conducted the climate simulations	Performed the experiments	Formal analysis|Investigation	YES
5897821	29610380	R.J.N.	2	designed and wrote the bulk of the paper	designed and wrote the bulk of the paper	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
5897821	29610380	S.B.	2	designed and wrote the bulk of the paper	designed and wrote the bulk of the paper	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
5897821	29610380	T.W.	2	conducted the coastal city analysis	conducted the coastal city analysis	Performed the experiments	Investigation	YES
6442005	30932366	B.M.N.	2	performed and designed the research study, analysed the data and wrote the paper	performed and designed the research study, analysed the data and wrote the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
6442005	30932366	C.M.S.R.	2	designed parts of the research study	designed parts of the research study	Conceived and designed the experiments	Methodology	YES
6442005	30932366	G.S.S.	2	performed parts of the research study and analysed the data	performed parts of the research study and analysed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6442005	30932366	J.S.	2	designed parts of the research study	designed parts of the research study	Conceived and designed the experiments	Methodology	YES
6442005	30932366	M.L.S.H.	2	contributed essential material	contributed essential material	Contributed reagents/materials/analysis tools	Resources	YES
6442005	30932366	M.V.	2	contributed essential material and designed parts of the research study	contributed essential material and designed parts of the research study	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Methodology|Resources	YES
6442005	30932366	P.R.	2	designed parts of the research study	designed parts of the research study	Conceived and designed the experiments	Methodology	YES
6442005	30932366	R.M.	2	designed the research study	designed the research study	Conceived and designed the experiments	Methodology	YES
6442005	30932366	R.R.C.E.S.	2	performed parts of the research study and analysed the data	performed parts of the research study and analysed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6442005	30932366	R.S-F	2	performed and designed parts the research study	performed and designed parts the research study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6442005	30932366	S.M.K.	2	performed parts of the research	performed parts of the research	Performed the experiments	Investigation	YES
6442005	30932366	T.B.H.G.	2	was involved in all aspects of the study	was involved in all aspects of the study	-	-	NO
5664084	29163584	SF	PLoS52	performed the research|analyzed the data	performed the research	Performed the experiments	Investigation	YES
5664084	29163584	SF	PLoS52	performed the research|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5664084	29163584	SM	PLoS52	performed the research	performed the research	Performed the experiments	Investigation	YES
5664084	29163584	XS	PLoS52	designed the research|wrote the paper	designed the research	Conceived and designed the experiments	Methodology	YES
5664084	29163584	XS	PLoS52	designed the research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5664084	29163584	YL	PLoS52	designed the research|performed the research|analyzed the data|wrote the paper	designed the research	Conceived and designed the experiments	Methodology	YES
5664084	29163584	YL	PLoS52	designed the research|performed the research|analyzed the data|wrote the paper	performed the research	Performed the experiments	Investigation	YES
5664084	29163584	YL	PLoS52	designed the research|performed the research|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5664084	29163584	YL	PLoS52	designed the research|performed the research|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5664084	29163584	ZZ	PLoS52	designed the research|wrote the paper	designed the research	Conceived and designed the experiments	Methodology	YES
5664084	29163584	ZZ	PLoS52	designed the research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411096	25915659	AB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4411096	25915659	AB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4411096	25915659	AB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411096	25915659	NG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411096	25915659	NG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411096	25915659	NG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411096	25915659	NG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411096	25915659	NG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411096	25915659	PV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411096	25915659	PV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411096	25915659	PV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411096	25915659	PV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411096	25915659	PV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411096	25915659	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411096	25915659	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411096	25915659	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411096	25915659	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411096	25915659	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411096	25915659	SSS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411096	25915659	SSS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411096	25915659	SSS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411096	25915659	SSS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411096	25915659	SSS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411096	25915659	VM	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4411096	25915659	VM	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5897822	29610381	Both authors	2	contributed to the editing and revision of the manuscript	contributed to the editing and revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5897822	29610381	P.F.	2	conceived of the study|both designed parts of the analysis conducted in the study	conceived of the study	Conceived and designed the experiments	Conceptualization	YES
5897822	29610381	P.F.	2	conceived of the study|both designed parts of the analysis conducted in the study	both designed parts of the analysis conducted in the study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5897822	29610381	R.J.M.	2	both designed parts of the analysis conducted in the study|conducted the analysis, produced the figures and produced a first draft of the manuscript	both designed parts of the analysis conducted in the study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5897822	29610381	R.J.M.	2	both designed parts of the analysis conducted in the study|conducted the analysis, produced the figures and produced a first draft of the manuscript	conducted the analysis, produced the figures and produced a first draft of the manuscript	Performed the experiments|Wrote the paper	Investigation|Visualization|Writing - Original Draft	YES
1820850	17380189	DG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1820850	17380189	DG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1820850	17380189	DG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1820850	17380189	DG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1820850	17380189	DG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1820850	17380189	EC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1820850	17380189	EC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1820850	17380189	EC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1820850	17380189	EC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1820850	17380189	HM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1820850	17380189	HM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1820850	17380189	HM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1820850	17380189	HM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1820850	17380189	HM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1820850	17380189	MY	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1820850	17380189	MY	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1820850	17380189	MY	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1820850	17380189	RM	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1820850	17380189	SG	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1820850	17380189	TT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1820850	17380189	TT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1820850	17380189	TT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1820850	17380189	TT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5502484	28693416	CM	2	were instrumental in the design of the study and contributed to the interpretation and writing of the manuscript	were instrumental in the design of the study and contributed to the interpretation and writing of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5502484	28693416	JC	2	were instrumental in the design of the study and contributed to the interpretation and writing of the manuscript	were instrumental in the design of the study and contributed to the interpretation and writing of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5502484	28693416	KH	2	oversaw the analytic pipeline of the rna seq analysis	oversaw the analytic pipeline of the rna seq analysis	Performed the experiments	Investigation|Supervision	YES
5502484	28693416	LL	2	were instrumental in the design of the study and contributed to the interpretation and writing of the manuscript	were instrumental in the design of the study and contributed to the interpretation and writing of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5502484	28693416	MD	2	analyzed and interpreted the rna seq data and was the primary author responsible for manuscript preparation	analyzed and interpreted the rna seq data and was the primary author responsible for manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5502484	28693416	SP	2	preprocessed the raw rna seq data and provided an analysis pipeline to generate the placental gene network	preprocessed the raw rna seq data and provided an analysis pipeline to generate the placental gene network	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5664085	29163591	H-LZ	PLoS5	Mined and analyzed the data|Performed sample preparation and culture experiments|Performed tissue collection, rna isolation and qrt-pcr analysis	Mined and analyzed the data	Analyzed the data	Formal analysis	YES
5664085	29163591	H-LZ	PLoS5	Mined and analyzed the data|Performed sample preparation and culture experiments|Performed tissue collection, rna isolation and qrt-pcr analysis	Performed sample preparation and culture experiments	Performed the experiments	Investigation	YES
5664085	29163591	H-LZ	PLoS5	Mined and analyzed the data|Performed sample preparation and culture experiments|Performed tissue collection, rna isolation and qrt-pcr analysis	Performed tissue collection, rna isolation and qrt-pcr analysis	Performed the experiments	Investigation	YES
5664085	29163591	H-RG	PLoS5	Performed the bioinformatics analysis|Performed sample preparation and culture experiments	Performed the bioinformatics analysis	Performed the experiments	Formal analysis|Investigation	YES
5664085	29163591	H-RG	PLoS5	Performed the bioinformatics analysis|Performed sample preparation and culture experiments	Performed sample preparation and culture experiments	Performed the experiments	Investigation	YES
5664085	29163591	LX	PLoS5	Mined and analyzed the data|Performed tissue collection, rna isolation and qrt-pcr analysis|Performed endogenous phytohormone content analysis	Mined and analyzed the data	Analyzed the data	Formal analysis	YES
5664085	29163591	LX	PLoS5	Mined and analyzed the data|Performed tissue collection, rna isolation and qrt-pcr analysis|Performed endogenous phytohormone content analysis	Performed tissue collection, rna isolation and qrt-pcr analysis	Performed the experiments	Investigation	YES
5664085	29163591	LX	PLoS5	Mined and analyzed the data|Performed tissue collection, rna isolation and qrt-pcr analysis|Performed endogenous phytohormone content analysis	Performed endogenous phytohormone content analysis	Performed the experiments	Investigation	YES
5664085	29163591	R-ZZ	PLoS5	Performed sample preparation and culture experiments|Performed tissue collection, rna isolation and qrt-pcr analysis	Performed sample preparation and culture experiments	Performed the experiments	Investigation	YES
5664085	29163591	R-ZZ	PLoS5	Performed sample preparation and culture experiments|Performed tissue collection, rna isolation and qrt-pcr analysis	Performed tissue collection, rna isolation and qrt-pcr analysis	Performed the experiments	Investigation	YES
5664085	29163591	X-QZ	PLoS5	Conceived and designed the experiments|Performed the bioinformatics analysis|Performed endogenous phytohormone content analysis|Wrote and edited the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5664085	29163591	X-QZ	PLoS5	Conceived and designed the experiments|Performed the bioinformatics analysis|Performed endogenous phytohormone content analysis|Wrote and edited the manuscript	Performed the bioinformatics analysis	Performed the experiments	Formal analysis|Investigation	YES
5664085	29163591	X-QZ	PLoS5	Conceived and designed the experiments|Performed the bioinformatics analysis|Performed endogenous phytohormone content analysis|Wrote and edited the manuscript	Performed endogenous phytohormone content analysis	Performed the experiments	Investigation	YES
5664085	29163591	X-QZ	PLoS5	Conceived and designed the experiments|Performed the bioinformatics analysis|Performed endogenous phytohormone content analysis|Wrote and edited the manuscript	Wrote and edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5664085	29163591	YL	PLoS5	Conceived and designed the experiments|Performed the bioinformatics analysis|Mined and analyzed the data|Performed sample preparation and culture experiments|Wrote and edited the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5664085	29163591	YL	PLoS5	Conceived and designed the experiments|Performed the bioinformatics analysis|Mined and analyzed the data|Performed sample preparation and culture experiments|Wrote and edited the manuscript	Performed the bioinformatics analysis	Performed the experiments	Formal analysis|Investigation	YES
5664085	29163591	YL	PLoS5	Conceived and designed the experiments|Performed the bioinformatics analysis|Mined and analyzed the data|Performed sample preparation and culture experiments|Wrote and edited the manuscript	Mined and analyzed the data	Analyzed the data	Formal analysis	YES
5664085	29163591	YL	PLoS5	Conceived and designed the experiments|Performed the bioinformatics analysis|Mined and analyzed the data|Performed sample preparation and culture experiments|Wrote and edited the manuscript	Performed sample preparation and culture experiments	Performed the experiments	Investigation	YES
5664085	29163591	YL	PLoS5	Conceived and designed the experiments|Performed the bioinformatics analysis|Mined and analyzed the data|Performed sample preparation and culture experiments|Wrote and edited the manuscript	Wrote and edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5664085	29163591	Z-SZ	PLoS5	Conceived and designed the experiments|Mined and analyzed the data|Wrote and edited the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5664085	29163591	Z-SZ	PLoS5	Conceived and designed the experiments|Mined and analyzed the data|Wrote and edited the manuscript	Mined and analyzed the data	Analyzed the data	Formal analysis	YES
5664085	29163591	Z-SZ	PLoS5	Conceived and designed the experiments|Mined and analyzed the data|Wrote and edited the manuscript	Wrote and edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4411097	25915041	DS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411097	25915041	DS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411097	25915041	DS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411097	25915041	DS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411097	25915041	DS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411097	25915041	GES	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4411097	25915041	GES	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4411097	25915041	GES	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411097	25915041	IE	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411097	25915041	JNM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4411097	25915041	JNM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4411097	25915041	JNM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411097	25915041	KS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4411097	25915041	KS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4411097	25915041	KS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411097	25915041	SC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411097	25915041	SC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411097	25915041	SC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411097	25915041	SC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411097	25915041	SC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1820851	17389909	DC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1820851	17389909	DC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1820851	17389909	DC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1820851	17389909	DC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1820851	17389909	JG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1820851	17389909	JG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1820851	17389909	JG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1820851	17389909	LD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1820851	17389909	LD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1820851	17389909	LD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1820851	17389909	LD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5502489	28693474	AJvdW	2	contributed most to research, analysis, formulation of ideas and writing	contributed most to research, analysis, formulation of ideas and writing	Conceived and designed the experiments|Wrote the paper	Conceptualization	YES
5502489	28693474	DAC	2	contributed formulation of ideas, direction and writing	contributed formulation of ideas, direction and writing	Conceived and designed the experiments|Wrote the paper	Conceptualization	YES
5502489	28693474	JBR	2	contributed formulation of ideas, direction and writing	contributed formulation of ideas, direction and writing	Conceived and designed the experiments|Wrote the paper	Conceptualization	YES
5502489	28693474	MWVG	2	contributed research, analysis, formulation of ideas and writing	contributed research, analysis, formulation of ideas and writing	Conceived and designed the experiments|Wrote the paper	Conceptualization	YES
5502489	28693474	OR	2	contributed direction and writing	contributed direction and writing	Wrote the paper	-	YES
5502489	28693474	TPM	2	contributed formulation of ideas and writing	contributed formulation of ideas and writing	Conceived and designed the experiments|Wrote the paper	Conceptualization	YES
5664361	29163570	DW	2	conceived the study|designed the study, interpreted the results, and wrote the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5664361	29163570	DW	2	conceived the study|designed the study, interpreted the results, and wrote the manuscript	designed the study, interpreted the results, and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5664361	29163570	SW	2	designed the study, interpreted the results, and wrote the manuscript	designed the study, interpreted the results, and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4411098	25915540	AA	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411098	25915540	AA	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411098	25915540	AOVB	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4411098	25915540	AOVB	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4411098	25915540	FS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411098	25915540	FS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411098	25915540	FS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411098	25915540	FS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411098	25915540	HR	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4411098	25915540	HR	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4411098	25915540	PA	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411098	25915540	PA	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411098	25915540	PA	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411098	25915540	PA	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411098	25915540	PC	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4411098	25915540	PC	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4411098	25915540	V. Dimitrova	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411098	25915540	V. Dimitrova	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411098	25915540	V. Dimitrova	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411098	25915540	V. Dimitrova	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411098	25915540	V. Djonov	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
6452026	30957420	All authors	2	approved the final version of the manuscript	approved the final version of the manuscript	-	-	NO
6452026	30957420	BC	2	contributed to data collection and edited manuscript	contributed to data collection and edited manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
6452026	30957420	CC	2	contributed to results interpretation and edited manuscript	contributed to results interpretation and edited manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
6452026	30957420	CK	2	contributed to data collection and edited manuscript	contributed to data collection and edited manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
6452026	30957420	GM	2	contributed to data collection and edited manuscript	contributed to data collection and edited manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
6452026	30957420	HH	2	contributed to data collection and edited manuscript	contributed to data collection and edited manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
6452026	30957420	JMB	2	designed the study|involved in study design, results interpretation and edited manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
6452026	30957420	JMB	2	designed the study|involved in study design, results interpretation and edited manuscript	involved in study design, results interpretation and edited manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
6452026	30957420	JN	2	contributed to data collection and edited manuscript	contributed to data collection and edited manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
6452026	30957420	JQ	2	contributed to data collection and edited manuscript	contributed to data collection and edited manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
6452026	30957420	JV	2	conducted all statistical analyses|contributed to statistical analysis, results interpretation and edited manuscript	conducted all statistical analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6452026	30957420	JV	2	conducted all statistical analyses|contributed to statistical analysis, results interpretation and edited manuscript	contributed to statistical analysis, results interpretation and edited manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
6452026	30957420	KN	2	designed the study|contributed to study design, results interpretation and edited manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
6452026	30957420	KN	2	designed the study|contributed to study design, results interpretation and edited manuscript	contributed to study design, results interpretation and edited manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
6452026	30957420	LO	2	contributed to data collection and edited manuscript	contributed to data collection and edited manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
6452026	30957420	NM	2	designed the study|contributed to study design, results interpretation and edited manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
6452026	30957420	NM	2	designed the study|contributed to study design, results interpretation and edited manuscript	contributed to study design, results interpretation and edited manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
6452026	30957420	NT	2	contributed to data collection and edited manuscript	contributed to data collection and edited manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
6452026	30957420	RH	2	designed the study|contributed to funding, study design, results interpretation and manuscript first draft	designed the study	Conceived and designed the experiments	Methodology	YES
6452026	30957420	RH	2	designed the study|contributed to funding, study design, results interpretation and manuscript first draft	contributed to funding, study design, results interpretation and manuscript first draft	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Funding acquisition|Methodology|Writing - Original Draft	YES
6452026	30957420	RM	2	contributed to data collection and edited manuscript	contributed to data collection and edited manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
6452026	30957420	SM	2	contributed to data collection and edited manuscript	contributed to data collection and edited manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
1824705	17389915	AL	PLoS5	Provided expert statistical input which made the paper possible	Provided expert statistical input which made the paper possible	Analyzed the data	Formal analysis	YES
1824705	17389915	DF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1824705	17389915	DF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1824705	17389915	DF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1824705	17389915	EF	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1824705	17389915	GW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1824705	17389915	GW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1824705	17389915	GW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1824705	17389915	GW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1824705	17389915	GW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5502491	28693467	AR	2	performed wet lab work including nucleotide extraction and sequencing	performed wet lab work including nucleotide extraction and sequencing	Performed the experiments	Investigation	YES
5502491	28693467	RR	2	identified the challenge and importance of aligning hyper-edited reads to repeats|provided interpretation of the repprofile results	identified the challenge and importance of aligning hyper-edited reads to repeats	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5502491	28693467	RR	2	identified the challenge and importance of aligning hyper-edited reads to repeats|provided interpretation of the repprofile results	provided interpretation of the repprofile results	Analyzed the data	Formal analysis	YES
5502491	28693467	RRs	2	understanding of hyper-editing	understanding of hyper-editing	Wrote the paper	Writing - Review & Editing	YES
5502491	28693467	WM	2	wrote and executed repprofile code	wrote and executed repprofile code	Performed the experiments|Wrote the paper	Investigation|Software|Writing - Original Draft	YES
5502491	28693467	YS	2	identified the challenge and importance of aligning hyper-edited reads to repeats|performed wet lab work including nucleotide extraction and sequencing	identified the challenge and importance of aligning hyper-edited reads to repeats	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5502491	28693467	YS	2	identified the challenge and importance of aligning hyper-edited reads to repeats|performed wet lab work including nucleotide extraction and sequencing	performed wet lab work including nucleotide extraction and sequencing	Performed the experiments	Investigation	YES
5502491	28693467	YSs	2	understanding of hyper-editing	understanding of hyper-editing	Wrote the paper	Writing - Review & Editing	YES
5664368	29163575	All the authors	2	listed made substantial intellectual contribution to the work, wrote the manuscript together and approved it for publication	listed made substantial intellectual contribution to the work, wrote the manuscript together and approved it for publication	Wrote the paper	Writing - Original Draft	YES
4564639	26413544	All authors	2	participated in the interpretation of the results and in writing the subsequent drafts	participated in the interpretation of the results and in writing the subsequent drafts	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4411099	25915422	AB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411099	25915422	AL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411099	25915422	AR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Initiated and obtained funding for the project	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411099	25915422	AR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Initiated and obtained funding for the project	Analyzed the data	Analyzed the data	Formal analysis	YES
4411099	25915422	AR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Initiated and obtained funding for the project	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411099	25915422	AR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Initiated and obtained funding for the project	Initiated and obtained funding for the project	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
4411099	25915422	DK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411099	25915422	G. Saper	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411099	25915422	G. Schuster	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Initiated and obtained funding for the project	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411099	25915422	G. Schuster	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Initiated and obtained funding for the project	Analyzed the data	Analyzed the data	Formal analysis	YES
4411099	25915422	G. Schuster	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Initiated and obtained funding for the project	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411099	25915422	G. Schuster	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Initiated and obtained funding for the project	Initiated and obtained funding for the project	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
4411099	25915422	MAS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411099	25915422	NA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Initiated and obtained funding for the project	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411099	25915422	NA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Initiated and obtained funding for the project	Analyzed the data	Analyzed the data	Formal analysis	YES
4411099	25915422	NA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Initiated and obtained funding for the project	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411099	25915422	NA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Initiated and obtained funding for the project	Initiated and obtained funding for the project	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
4411099	25915422	RB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411099	25915422	RIP	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411099	25915422	RIP	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411099	25915422	RIP	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411099	25915422	SL	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4411099	25915422	SL	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5897827	29610386	A.M.	5	led analysis and writing of ss2	led analysis and writing of ss2	Wrote the paper	-	YES
5897827	29610386	J.P.	5	led analysis and writing of ss2	led analysis and writing of ss2	Wrote the paper	-	YES
5897827	29610386	P.S.	5	coordinated contributions and led analysis and writing of ss3	coordinated contributions and led analysis and writing of ss3	Wrote the paper	Project administration	YES
6452919	30958638	All authors	2	contributed substantially to the conception, design, analysis and interpretation of data, and participated in the preparation and review of drafts of this manuscript, and gave their final consent to the publication of the final version	contributed substantially to the conception, design, analysis and interpretation of data, and participated in the preparation and review of drafts of this manuscript, and gave their final consent to the publication of the final version	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Resources|Writing - Original Draft|Writing - Review & Editing	YES
1824706	17389920	DL	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1824706	17389920	GR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1824706	17389920	GR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1824706	17389920	GR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1824706	17389920	HS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1824706	17389920	HS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1824706	17389920	HS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1824706	17389920	HS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1824706	17389920	JM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1824706	17389920	JM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1824706	17389920	JM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1824706	17389920	JY	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1824706	17389920	JY	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1824706	17389920	JY	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1824706	17389920	RC	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
3655585	23710183	J. Lindner	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
3655585	23710183	K. A. Meissner	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
5504746	28693460	DM	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|contributed to the writing of the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5504746	28693460	DM	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|contributed to the writing of the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5504746	28693460	DM	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|contributed to the writing of the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5504746	28693460	DM	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|contributed to the writing of the manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5504746	28693460	KG	PLoS52	contributed reagents/materials/analysis tools	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5504746	28693460	SM	PLoS52	conceived and designed the experiments|contributed reagents/materials/analysis tools|contributed to the writing of the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5504746	28693460	SM	PLoS52	conceived and designed the experiments|contributed reagents/materials/analysis tools|contributed to the writing of the manuscript	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5504746	28693460	SM	PLoS52	conceived and designed the experiments|contributed reagents/materials/analysis tools|contributed to the writing of the manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5504746	28693460	ZM	PLoS52	contributed reagents/materials/analysis tools|contributed to the writing of the manuscript	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5504746	28693460	ZM	PLoS52	contributed reagents/materials/analysis tools|contributed to the writing of the manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
4411100	25915424	CPE	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411100	25915424	CPE	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411100	25915424	EL-Z	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411100	25915424	EL-Z	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411100	25915424	EL-Z	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411100	25915424	FN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411100	25915424	FN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411100	25915424	FN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411100	25915424	FN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411100	25915424	FN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411100	25915424	JA	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411100	25915424	JA	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411100	25915424	JA	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411100	25915424	JA	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411100	25915424	RC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411100	25915424	RC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4411100	25915424	RC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4411100	25915424	RC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5664426	29163565	AM	2	conducted the field experiment and acquired the data|they all approved the manuscript to be published and agreed to be accountable for all aspects of the work in ensuring the questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	conducted the field experiment and acquired the data	Performed the experiments	Investigation	YES
5664426	29163565	AM	2	conducted the field experiment and acquired the data|they all approved the manuscript to be published and agreed to be accountable for all aspects of the work in ensuring the questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	they all approved the manuscript to be published and agreed to be accountable for all aspects of the work in ensuring the questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	-	-	NO
5664426	29163565	BC	2	took part in designing the field and pot experiment and drafting the work, and also provided the 50 oilseed rape genotypes|they all approved the manuscript to be published and agreed to be accountable for all aspects of the work in ensuring the questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	took part in designing the field and pot experiment and drafting the work, and also provided the 50 oilseed rape genotypes	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5664426	29163565	BC	2	took part in designing the field and pot experiment and drafting the work, and also provided the 50 oilseed rape genotypes|they all approved the manuscript to be published and agreed to be accountable for all aspects of the work in ensuring the questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	they all approved the manuscript to be published and agreed to be accountable for all aspects of the work in ensuring the questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	-	-	NO
5664426	29163565	HH	2	analyzed the data and wrote the manuscript|they all approved the manuscript to be published and agreed to be accountable for all aspects of the work in ensuring the questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5664426	29163565	HH	2	analyzed the data and wrote the manuscript|they all approved the manuscript to be published and agreed to be accountable for all aspects of the work in ensuring the questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	they all approved the manuscript to be published and agreed to be accountable for all aspects of the work in ensuring the questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	-	-	NO
5664426	29163565	HT	2	edited the manuscript|they all approved the manuscript to be published and agreed to be accountable for all aspects of the work in ensuring the questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5664426	29163565	HT	2	edited the manuscript|they all approved the manuscript to be published and agreed to be accountable for all aspects of the work in ensuring the questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	they all approved the manuscript to be published and agreed to be accountable for all aspects of the work in ensuring the questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	-	-	NO
5664426	29163565	LC	2	took part in designing the pot experiment, conducted it, acquired the data and participated in drafting the work|they all approved the manuscript to be published and agreed to be accountable for all aspects of the work in ensuring the questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	took part in designing the pot experiment, conducted it, acquired the data and participated in drafting the work	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5664426	29163565	LC	2	took part in designing the pot experiment, conducted it, acquired the data and participated in drafting the work|they all approved the manuscript to be published and agreed to be accountable for all aspects of the work in ensuring the questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	they all approved the manuscript to be published and agreed to be accountable for all aspects of the work in ensuring the questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	-	-	NO
5664426	29163565	RY	2	took part in designing the field experiment, conducted it, acquired the data and participated in drafting the work|they all approved the manuscript to be published and agreed to be accountable for all aspects of the work in ensuring the questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	took part in designing the field experiment, conducted it, acquired the data and participated in drafting the work	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5664426	29163565	RY	2	took part in designing the field experiment, conducted it, acquired the data and participated in drafting the work|they all approved the manuscript to be published and agreed to be accountable for all aspects of the work in ensuring the questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	they all approved the manuscript to be published and agreed to be accountable for all aspects of the work in ensuring the questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	-	-	NO
5664426	29163565	XW	2	took part in designing the field and pot experiment and drafting the work, and also provided the 50 oilseed rape genotypes|they all approved the manuscript to be published and agreed to be accountable for all aspects of the work in ensuring the questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	took part in designing the field and pot experiment and drafting the work, and also provided the 50 oilseed rape genotypes	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5664426	29163565	XW	2	took part in designing the field and pot experiment and drafting the work, and also provided the 50 oilseed rape genotypes|they all approved the manuscript to be published and agreed to be accountable for all aspects of the work in ensuring the questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	they all approved the manuscript to be published and agreed to be accountable for all aspects of the work in ensuring the questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	-	-	NO
5664426	29163565	YG	2	designed the pot and field experiments, conducted it, acquired and analyzed the data|also drafted the work and revised the manuscript critically|they all approved the manuscript to be published and agreed to be accountable for all aspects of the work in ensuring the questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	designed the pot and field experiments, conducted it, acquired and analyzed the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5664426	29163565	YG	2	designed the pot and field experiments, conducted it, acquired and analyzed the data|also drafted the work and revised the manuscript critically|they all approved the manuscript to be published and agreed to be accountable for all aspects of the work in ensuring the questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	also drafted the work and revised the manuscript critically	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5664426	29163565	YG	2	designed the pot and field experiments, conducted it, acquired and analyzed the data|also drafted the work and revised the manuscript critically|they all approved the manuscript to be published and agreed to be accountable for all aspects of the work in ensuring the questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	they all approved the manuscript to be published and agreed to be accountable for all aspects of the work in ensuring the questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	-	-	NO
5664426	29163565	YL	2	took part in designing the pot experiment, conducted it, acquired the data and participated in drafting the work|they all approved the manuscript to be published and agreed to be accountable for all aspects of the work in ensuring the questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	took part in designing the pot experiment, conducted it, acquired the data and participated in drafting the work	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5664426	29163565	YL	2	took part in designing the pot experiment, conducted it, acquired the data and participated in drafting the work|they all approved the manuscript to be published and agreed to be accountable for all aspects of the work in ensuring the questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	they all approved the manuscript to be published and agreed to be accountable for all aspects of the work in ensuring the questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	-	-	NO
5897829	29610369	J.C.S.	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
5897829	29610369	P.C.F.	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
6452920	30958644	ALD	PLoS52	reviewed and extracted guidelines|designed the protocol|analysed the data|wrote the manuscript	reviewed and extracted guidelines	Performed the experiments	Investigation	YES
6452920	30958644	ALD	PLoS52	reviewed and extracted guidelines|designed the protocol|analysed the data|wrote the manuscript	designed the protocol	Conceived and designed the experiments	Methodology	YES
6452920	30958644	ALD	PLoS52	reviewed and extracted guidelines|designed the protocol|analysed the data|wrote the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
6452920	30958644	ALD	PLoS52	reviewed and extracted guidelines|designed the protocol|analysed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6452920	30958644	CJ	PLoS52	designed the protocol|all provided substantial input and edits to the manuscript	designed the protocol	Conceived and designed the experiments	Methodology	YES
6452920	30958644	CJ	PLoS52	designed the protocol|all provided substantial input and edits to the manuscript	all provided substantial input and edits to the manuscript	Wrote the paper	Writing - Review & Editing	YES
6452920	30958644	CL	PLoS52	all provided substantial input and edits to the manuscript	all provided substantial input and edits to the manuscript	Wrote the paper	Writing - Review & Editing	YES
6452920	30958644	CQ	PLoS52	reviewed and extracted guidelines|reviewed and commented on the protocol|all provided substantial input and edits to the manuscript	reviewed and extracted guidelines	Performed the experiments	Investigation	YES
6452920	30958644	CQ	PLoS52	reviewed and extracted guidelines|reviewed and commented on the protocol|all provided substantial input and edits to the manuscript	reviewed and commented on the protocol	Conceived and designed the experiments	Methodology	YES
6452920	30958644	CQ	PLoS52	reviewed and extracted guidelines|reviewed and commented on the protocol|all provided substantial input and edits to the manuscript	all provided substantial input and edits to the manuscript	Wrote the paper	Writing - Review & Editing	YES
6452920	30958644	IN	PLoS52	all provided substantial input and edits to the manuscript	all provided substantial input and edits to the manuscript	Wrote the paper	Writing - Review & Editing	YES
6452920	30958644	KAT	PLoS52	reviewed and extracted guidelines|designed the protocol|analysed the data|wrote the manuscript	reviewed and extracted guidelines	Performed the experiments	Investigation	YES
6452920	30958644	KAT	PLoS52	reviewed and extracted guidelines|designed the protocol|analysed the data|wrote the manuscript	designed the protocol	Conceived and designed the experiments	Methodology	YES
6452920	30958644	KAT	PLoS52	reviewed and extracted guidelines|designed the protocol|analysed the data|wrote the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
6452920	30958644	KAT	PLoS52	reviewed and extracted guidelines|designed the protocol|analysed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6452920	30958644	MON	PLoS52	all provided substantial input and edits to the manuscript	all provided substantial input and edits to the manuscript	Wrote the paper	Writing - Review & Editing	YES
6452920	30958644	RB	PLoS52	reviewed and commented on the protocol|all provided substantial input and edits to the manuscript	reviewed and commented on the protocol	Conceived and designed the experiments	Methodology	YES
6452920	30958644	RB	PLoS52	reviewed and commented on the protocol|all provided substantial input and edits to the manuscript	all provided substantial input and edits to the manuscript	Wrote the paper	Writing - Review & Editing	YES
6452920	30958644	SE	PLoS52	reviewed and commented on the protocol|all provided substantial input and edits to the manuscript	reviewed and commented on the protocol	Conceived and designed the experiments	Methodology	YES
6452920	30958644	SE	PLoS52	reviewed and commented on the protocol|all provided substantial input and edits to the manuscript	all provided substantial input and edits to the manuscript	Wrote the paper	Writing - Review & Editing	YES
1824707	17389911	AA	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1824707	17389911	AA	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1824707	17389911	AK	PLoS5	Gave feedback on the manuscript	Gave feedback on the manuscript	-	-	NO
1824707	17389911	GH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1824707	17389911	GH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1824707	17389911	GH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1824707	17389911	GH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1824707	17389911	GH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1824707	17389911	NM	PLoS5	Gave feedback on the manuscript	Gave feedback on the manuscript	-	-	NO
4411102	25915507	AP	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4411102	25915507	KVRR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411102	25915507	KVRR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411102	25915507	KVRR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411102	25915507	MP	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4411102	25915507	SKC	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411102	25915507	SKC	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4411102	25915507	TB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411102	25915507	TB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411102	25915507	TB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411102	25915507	TB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5504793	28693539	BSFM	2	performed the analysis of experiments and wrote the first version of the manuscript	performed the analysis of experiments and wrote the first version of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5504793	28693539	DG	2	generated the snp data, designed and coordinated the study and edited the final version of the manuscript	generated the snp data, designed and coordinated the study and edited the final version of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Project administration|Writing - Review & Editing	YES
5504793	28693539	EPF	2	conducted the field experiments and collected the phenotype data	conducted the field experiments and collected the phenotype data	Performed the experiments	Investigation	YES
5504793	28693539	JEAF	2	made substantial contributions to the bioinformatics, genomic prediction analysis and interpretation of data	made substantial contributions to the bioinformatics, genomic prediction analysis and interpretation of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5504793	28693539	LGN	2	made substantial contributions to the bioinformatics, genomic prediction analysis and interpretation of data|was involved in manuscript editing	made substantial contributions to the bioinformatics, genomic prediction analysis and interpretation of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5504793	28693539	LGN	2	made substantial contributions to the bioinformatics, genomic prediction analysis and interpretation of data|was involved in manuscript editing	was involved in manuscript editing	Wrote the paper	Writing - Review & Editing	YES
5504793	28693539	MFRRJr	2	contributed to the interpretation of results	contributed to the interpretation of results	Analyzed the data	Formal analysis	YES
5504793	28693539	MK	2	contributed to the interpretation of results	contributed to the interpretation of results	Analyzed the data	Formal analysis	YES
5504793	28693539	PETS	2	conducted the field experiments and collected the phenotype data	conducted the field experiments and collected the phenotype data	Performed the experiments	Investigation	YES
5504793	28693539	PRM	2	contributed to the interpretation of results	contributed to the interpretation of results	Analyzed the data	Formal analysis	YES
5897830	29610370	F.P.	PLoS52	conducted the statistical analysis, and created the figures|created the projections|wrote the paper	conducted the statistical analysis, and created the figures	Analyzed the data	Formal analysis|Visualization	YES
5897830	29610370	F.P.	PLoS52	conducted the statistical analysis, and created the figures|created the projections|wrote the paper	created the projections	-	-	NO
5897830	29610370	F.P.	PLoS52	conducted the statistical analysis, and created the figures|created the projections|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5897830	29610370	K.H.	PLoS52	generated and extracted the climate simulation data|wrote the paper	generated and extracted the climate simulation data	Performed the experiments	Formal analysis|Investigation	YES
5897830	29610370	K.H.	PLoS52	generated and extracted the climate simulation data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5897830	29610370	K.T.	PLoS52	created the projections|wrote the paper	created the projections	-	-	NO
5897830	29610370	K.T.	PLoS52	created the projections|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5897830	29610370	M.R.A.	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5897830	29610370	M.S.	PLoS52	conducted the statistical analysis, and created the figures|generated the climate estimation data|generated and extracted the climate simulation data|wrote the paper	conducted the statistical analysis, and created the figures	Analyzed the data	Formal analysis|Visualization	YES
5897830	29610370	M.S.	PLoS52	conducted the statistical analysis, and created the figures|generated the climate estimation data|generated and extracted the climate simulation data|wrote the paper	generated the climate estimation data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5897830	29610370	M.S.	PLoS52	conducted the statistical analysis, and created the figures|generated the climate estimation data|generated and extracted the climate simulation data|wrote the paper	generated and extracted the climate simulation data	Performed the experiments	Formal analysis|Investigation	YES
5897830	29610370	M.S.	PLoS52	conducted the statistical analysis, and created the figures|generated the climate estimation data|generated and extracted the climate simulation data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6462805	30983155	AEG	2	designed the study and wrote the protocol with input from all authors|designed the surveys and data collection tools	designed the study and wrote the protocol with input from all authors	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
6462805	30983155	AEG	2	designed the study and wrote the protocol with input from all authors|designed the surveys and data collection tools	designed the surveys and data collection tools	Conceived and designed the experiments|Performed the experiments	Investigation	YES
6462805	30983155	All authors	2	contributed to the interpretation of results and approved the manuscript	contributed to the interpretation of results and approved the manuscript	Analyzed the data	Formal analysis	YES
6462805	30983155	BG	2	oversaw recruitment of couples at clinical sites	oversaw recruitment of couples at clinical sites	Performed the experiments	Investigation|Supervision	YES
6462805	30983155	BKT	2	oversaw recruitment of couples at clinical sites	oversaw recruitment of couples at clinical sites	Performed the experiments	Investigation|Supervision	YES
6462805	30983155	BRB	2	designed the study and wrote the protocol with input from all authors|designed the surveys and data collection tools|analysed the data and drafted the manuscript	designed the study and wrote the protocol with input from all authors	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
6462805	30983155	BRB	2	designed the study and wrote the protocol with input from all authors|designed the surveys and data collection tools|analysed the data and drafted the manuscript	designed the surveys and data collection tools	Conceived and designed the experiments|Performed the experiments	Investigation	YES
6462805	30983155	BRB	2	designed the study and wrote the protocol with input from all authors|designed the surveys and data collection tools|analysed the data and drafted the manuscript	analysed the data and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6462805	30983155	CKF	2	oversaw recruitment of couples at clinical sites	oversaw recruitment of couples at clinical sites	Performed the experiments	Investigation|Supervision	YES
6462805	30983155	DJT	2	oversaw recruitment of couples at clinical sites	oversaw recruitment of couples at clinical sites	Performed the experiments	Investigation|Supervision	YES
6462805	30983155	FJ	2	designed the study and wrote the protocol with input from all authors|designed the surveys and data collection tools	designed the study and wrote the protocol with input from all authors	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
6462805	30983155	FJ	2	designed the study and wrote the protocol with input from all authors|designed the surveys and data collection tools	designed the surveys and data collection tools	Conceived and designed the experiments|Performed the experiments	Investigation	YES
6462805	30983155	GPP	2	designed the study and wrote the protocol with input from all authors|designed the surveys and data collection tools	designed the study and wrote the protocol with input from all authors	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
6462805	30983155	GPP	2	designed the study and wrote the protocol with input from all authors|designed the surveys and data collection tools	designed the surveys and data collection tools	Conceived and designed the experiments|Performed the experiments	Investigation	YES
6462805	30983155	JH	2	oversaw recruitment of couples at clinical sites	oversaw recruitment of couples at clinical sites	Performed the experiments	Investigation|Supervision	YES
6462805	30983155	NP	2	oversaw recruitment of couples at clinical sites	oversaw recruitment of couples at clinical sites	Performed the experiments	Investigation|Supervision	YES
5665000	29163581	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5665000	29163581	HF	PLoS52	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5665000	29163581	JM	PLoS52	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5665000	29163581	JY	PLoS52	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5665000	29163581	LY	PLoS52	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5665000	29163581	LZ	PLoS52	coordinated and supervised the project	coordinated and supervised the project	-	Project administration|Supervision	YES
5665000	29163581	QS	PLoS52	corrected the manuscript	corrected the manuscript	Wrote the paper	Writing - Review & Editing	YES
5665000	29163581	SL	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5665000	29163581	TC	PLoS52	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5665000	29163581	TG	PLoS52	corrected the manuscript	corrected the manuscript	Wrote the paper	Writing - Review & Editing	YES
5665000	29163581	WJL	PLoS52	corrected the manuscript	corrected the manuscript	Wrote the paper	Writing - Review & Editing	YES
5665000	29163581	WLL	PLoS52	corrected the manuscript	corrected the manuscript	Wrote the paper	Writing - Review & Editing	YES
5665000	29163581	XC	PLoS52	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5665000	29163581	XL	PLoS52	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5665000	29163581	YC	PLoS52	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5665000	29163581	YD	PLoS52	designed the experiments and wrote the manuscript|analyzed the data|performed experiments	designed the experiments and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5665000	29163581	YD	PLoS52	designed the experiments and wrote the manuscript|analyzed the data|performed experiments	analyzed the data	Analyzed the data	Formal analysis	YES
5665000	29163581	YD	PLoS52	designed the experiments and wrote the manuscript|analyzed the data|performed experiments	performed experiments	Performed the experiments	Investigation	YES
4568032	26413501	Leman Tomak	2	contributed to this work	contributed to this work	-	-	NO
4568032	26413501	MD	2	contributed to this work|contributed to this work	contributed to this work	-	-	NO
4568032	26413501	MD	2	contributed to this work|contributed to this work	contributed to this work	-	-	NO
4568032	26413501	Ph.D.	2	contributed to this work|contributed to this work	contributed to this work	-	-	NO
4568032	26413501	Ph.D.	2	contributed to this work|contributed to this work	contributed to this work	-	-	NO
4568032	26413501	Yilmaz Tomak	2	contributed to this work	contributed to this work	-	-	NO
4568032	26413501	Yuksel Bek	2	contributed to this work	contributed to this work	-	-	NO
4411103	25915066	CTS	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411103	25915066	CTS	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411103	25915066	KPW	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411103	25915066	LA	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411103	25915066	LA	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411103	25915066	MAC	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411103	25915066	MAC	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411103	25915066	MKL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411103	25915066	MKL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411103	25915066	MKL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411103	25915066	MKL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411103	25915066	OGJ	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411103	25915066	OJG	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411103	25915066	PA	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3807542	24198731	Dianwei Wu	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
3807542	24198731	Jiyan Su	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
3807542	24198731	Lirong Tan	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
1824708	17396162	JD	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1824708	17396162	JD	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1824708	17396162	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1824708	17396162	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1824708	17396162	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1824708	17396162	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5666294	29163563	AR	PLoS52	helped with the conducted the experiments and received	helped with the conducted the experiments and received	Performed the experiments	Investigation	YES
5666294	29163563	HNB	PLoS52	analyzed the data and formatted the figures	analyzed the data and formatted the figures	Analyzed the data	Formal analysis|Visualization	YES
5666294	29163563	KZ	PLoS52	helped with the conducted the experiments and received	helped with the conducted the experiments and received	Performed the experiments	Investigation	YES
5666294	29163563	LC	PLoS52	conceived and designed the study|reviewed and edited the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5666294	29163563	LC	PLoS52	conceived and designed the study|reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5666294	29163563	MHR	PLoS52	conducted the experiments and received|wrote the paper	conducted the experiments and received	Performed the experiments	Investigation	YES
5666294	29163563	MHR	PLoS52	conducted the experiments and received|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5666294	29163563	MSR	PLoS52	analyzed the data and formatted the figures	analyzed the data and formatted the figures	Analyzed the data	Formal analysis|Visualization	YES
5666294	29163563	SC	PLoS52	conceived and designed the study|reviewed and edited the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5666294	29163563	SC	PLoS52	conceived and designed the study|reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5666294	29163563	WW	PLoS52	guided the observation of the stigma exsertion rates	guided the observation of the stigma exsertion rates	Performed the experiments	Investigation|Supervision	YES
5666294	29163563	XZ	PLoS52	guided the observation of the stigma exsertion rates	guided the observation of the stigma exsertion rates	Performed the experiments	Investigation|Supervision	YES
5666294	29163563	YC	PLoS52	analyzed the data and formatted the figures	analyzed the data and formatted the figures	Analyzed the data	Formal analysis|Visualization	YES
5666294	29163563	YZ	PLoS52	conceived and designed the study|guided the observation of the stigma exsertion rates|wrote the paper	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5666294	29163563	YZ	PLoS52	conceived and designed the study|guided the observation of the stigma exsertion rates|wrote the paper	guided the observation of the stigma exsertion rates	Performed the experiments	Investigation|Supervision	YES
5666294	29163563	YZ	PLoS52	conceived and designed the study|guided the observation of the stigma exsertion rates|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5666294	29163563	all the authors	PLoS52	and approved	and approved	-	-	NO
5505149	28697749	AS	2	annotated genomes, and performed analysis|wrote the manuscript	annotated genomes, and performed analysis	Performed the experiments	Investigation	YES
5505149	28697749	AS	2	annotated genomes, and performed analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5505149	28697749	CM	2	identified and characterized the strains	identified and characterized the strains	Performed the experiments	Investigation	YES
5505149	28697749	EPCR	2	wrote the manuscript|helped with the genome analysis	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5505149	28697749	EPCR	2	wrote the manuscript|helped with the genome analysis	helped with the genome analysis	-	-	NO
5505149	28697749	MT	2	annotated genomes, and performed analysis|wrote the manuscript	annotated genomes, and performed analysis	Performed the experiments	Investigation	YES
5505149	28697749	MT	2	annotated genomes, and performed analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5505149	28697749	PJS	2	conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5505149	28697749	RT	2	helped with the genome analysis	helped with the genome analysis	-	-	NO
5505149	28697749	SB	2	helped with the genome analysis	helped with the genome analysis	-	-	NO
5505149	28697749	TP	2	conceived the study|wrote the manuscript|identified and characterized the strains	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5505149	28697749	TP	2	conceived the study|wrote the manuscript|identified and characterized the strains	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5505149	28697749	TP	2	conceived the study|wrote the manuscript|identified and characterized the strains	identified and characterized the strains	Performed the experiments	Investigation	YES
5505149	28697749	VP	2	helped with the genome analysis	helped with the genome analysis	-	-	NO
6462807	30983147	ARB	PLoS52	analysed the data|wrote the first draft of the paper	analysed the data	Analyzed the data	Formal analysis	YES
6462807	30983147	ARB	PLoS52	analysed the data|wrote the first draft of the paper	wrote the first draft of the paper	Wrote the paper	Writing - Original Draft	YES
6462807	30983147	All authors	PLoS52	contributed to and approved the final manuscript	contributed to and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6462807	30983147	GR	PLoS52	collected data	collected data	Performed the experiments	Investigation	YES
6462807	30983147	JLS	PLoS52	designed the research and collected data|analysed the data|wrote the first draft of the paper	designed the research and collected data	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6462807	30983147	JLS	PLoS52	designed the research and collected data|analysed the data|wrote the first draft of the paper	analysed the data	Analyzed the data	Formal analysis	YES
6462807	30983147	JLS	PLoS52	designed the research and collected data|analysed the data|wrote the first draft of the paper	wrote the first draft of the paper	Wrote the paper	Writing - Original Draft	YES
6462807	30983147	KAY	PLoS52	analysed the data|wrote the first draft of the paper	analysed the data	Analyzed the data	Formal analysis	YES
6462807	30983147	KAY	PLoS52	analysed the data|wrote the first draft of the paper	wrote the first draft of the paper	Wrote the paper	Writing - Original Draft	YES
6462807	30983147	SO	PLoS52	collected data	collected data	Performed the experiments	Investigation	YES
1824709	17389922	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1824709	17389922	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1824709	17389922	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1824709	17389922	EC	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1824709	17389922	EC	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1824709	17389922	EC	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1824709	17389922	EC	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1824709	17389922	FC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1824709	17389922	FC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1824709	17389922	FC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1824709	17389922	JR	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1824709	17389922	JR	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1824709	17389922	JR	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1824709	17389922	MV	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1824709	17389922	MV	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1824709	17389922	RD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1824709	17389922	RD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1824709	17389922	RD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3492062	22901717	MJM	2	participated in planning and interpretation of experiments	participated in planning and interpretation of experiments	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
3492062	22901717	PW	2	participated in interpretation of experiments and finishing of the manuscript	participated in interpretation of experiments and finishing of the manuscript	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3492062	22901717	TK	2	participated in planning and interpretation of experiments	participated in planning and interpretation of experiments	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
3492062	22901717	TOJ	2	was main responsible for planning and performing the experiments, and drafted the manuscript	was main responsible for planning and performing the experiments, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5915646	29661973	A.-M.A.v.V.	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
3492069	23046725	All authors	2	contributed to data interpretation and writing of the manuscript	contributed to data interpretation and writing of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3492069	23046725	FAR	2	guided the research	guided the research	-	Supervision	YES
3492069	23046725	WMM	2	guided the research	guided the research	-	Supervision	YES
4411104	25915048	DHJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411104	25915048	DHJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411104	25915048	DHJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411104	25915048	DHJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411104	25915048	HSC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411104	25915048	J-HK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411104	25915048	J-HK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4411104	25915048	J-HK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4411104	25915048	JCP	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411104	25915048	SKL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411104	25915048	SKS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411104	25915048	YCL	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411104	25915048	YCL	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6462808	30983152	A.M.S.	2	finalized the literature review and drafted the paper	finalized the literature review and drafted the paper	Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
6462808	30983152	B.R.P.	2	finalized the literature review and drafted the paper|finalized, formatted and submitted the paper as per journal guidelines	finalized the literature review and drafted the paper	Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
6462808	30983152	B.R.P.	2	finalized the literature review and drafted the paper|finalized, formatted and submitted the paper as per journal guidelines	finalized, formatted and submitted the paper as per journal guidelines	Wrote the paper	Writing - Review & Editing	YES
6462808	30983152	C.L.	2	provided critical data and technical supply chain input into the paper	provided critical data and technical supply chain input into the paper	Contributed reagents/materials/analysis tools	Resources	YES
6462808	30983152	C.M.	2	conceived and outlined paper and conducted initial literature review|finalized the literature review and drafted the paper|finalized, formatted and submitted the paper as per journal guidelines	conceived and outlined paper and conducted initial literature review	Conceived and designed the experiments|Performed the experiments	Conceptualization|Formal analysis|Investigation	YES
6462808	30983152	C.M.	2	conceived and outlined paper and conducted initial literature review|finalized the literature review and drafted the paper|finalized, formatted and submitted the paper as per journal guidelines	finalized the literature review and drafted the paper	Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
6462808	30983152	C.M.	2	conceived and outlined paper and conducted initial literature review|finalized the literature review and drafted the paper|finalized, formatted and submitted the paper as per journal guidelines	finalized, formatted and submitted the paper as per journal guidelines	Wrote the paper	Writing - Review & Editing	YES
6462808	30983152	L.O.	2	conceived and outlined paper and conducted initial literature review|finalized the literature review and drafted the paper	conceived and outlined paper and conducted initial literature review	Conceived and designed the experiments|Performed the experiments	Conceptualization|Formal analysis|Investigation	YES
6462808	30983152	L.O.	2	conceived and outlined paper and conducted initial literature review|finalized the literature review and drafted the paper	finalized the literature review and drafted the paper	Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
6462808	30983152	N.S.	2	finalized the literature review and drafted the paper	finalized the literature review and drafted the paper	Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
6462808	30983152	R.G.	2	conceived and outlined paper and conducted initial literature review|finalized the literature review and drafted the paper|finalized, formatted and submitted the paper as per journal guidelines	conceived and outlined paper and conducted initial literature review	Conceived and designed the experiments|Performed the experiments	Conceptualization|Formal analysis|Investigation	YES
6462808	30983152	R.G.	2	conceived and outlined paper and conducted initial literature review|finalized the literature review and drafted the paper|finalized, formatted and submitted the paper as per journal guidelines	finalized the literature review and drafted the paper	Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
6462808	30983152	R.G.	2	conceived and outlined paper and conducted initial literature review|finalized the literature review and drafted the paper|finalized, formatted and submitted the paper as per journal guidelines	finalized, formatted and submitted the paper as per journal guidelines	Wrote the paper	Writing - Review & Editing	YES
5670102	29163571	JS	2	contributed equally to the writing of this review|agree to be accountable for the content of the work	contributed equally to the writing of this review	Wrote the paper	Writing - Review & Editing	YES
5670102	29163571	JS	2	contributed equally to the writing of this review|agree to be accountable for the content of the work	agree to be accountable for the content of the work	-	-	NO
5670102	29163571	SL	2	contributed equally to the writing of this review|agree to be accountable for the content of the work	contributed equally to the writing of this review	Wrote the paper	Writing - Review & Editing	YES
5670102	29163571	SL	2	contributed equally to the writing of this review|agree to be accountable for the content of the work	agree to be accountable for the content of the work	-	-	NO
1824710	17389912	AR	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1824710	17389912	AR	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1824710	17389912	AW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1824710	17389912	AW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1824710	17389912	BD	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1824710	17389912	BD	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1824710	17389912	BD	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1824710	17389912	BD	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1824710	17389912	BW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1824710	17389912	BW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1824710	17389912	BW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1824710	17389912	BW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1824710	17389912	CV	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1824710	17389912	CV	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1824710	17389912	DC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1824710	17389912	DC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1824710	17389912	DS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1824710	17389912	DS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1824710	17389912	ER	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1824710	17389912	ER	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1824710	17389912	GR	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1824710	17389912	GR	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1824710	17389912	MA	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Wrote the paper|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1824710	17389912	MA	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Wrote the paper|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1824710	17389912	MA	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Wrote the paper|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1824710	17389912	MA	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Wrote the paper|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1824710	17389912	MA	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Wrote the paper|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1824710	17389912	MA	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Wrote the paper|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1824710	17389912	MA	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Wrote the paper|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1824710	17389912	MJ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1824710	17389912	MJ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1824710	17389912	NB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1824710	17389912	NB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1824710	17389912	RD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1824710	17389912	RD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1824710	17389912	RD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1824710	17389912	RD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1824710	17389912	RG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1824710	17389912	RG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1824710	17389912	TF	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1824710	17389912	TF	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
550646	15717931	BL	1	Concepts and supervision	Concepts and supervision	Conceived and designed the experiments	Conceptualization|Supervision	YES
550646	15717931	CW	1	Concepts and supervision|Running costs|Manus preparation	Concepts and supervision	Conceived and designed the experiments	Conceptualization|Supervision	YES
550646	15717931	CW	1	Concepts and supervision|Running costs|Manus preparation	Running costs	-	-	NO
550646	15717931	CW	1	Concepts and supervision|Running costs|Manus preparation	Manus preparation	-	-	NO
550646	15717931	MAF	1	Luciferase expression	Luciferase expression	Performed the experiments	Investigation	YES
550646	15717931	PGE	1	Manus preparation	Manus preparation	-	-	NO
550646	15717931	SM-T	1	Concepts and supervision	Concepts and supervision	Conceived and designed the experiments	Conceptualization|Supervision	YES
550646	15717931	SMT	1	Running costs|Manus preparation	Running costs	-	-	NO
550646	15717931	SMT	1	Running costs|Manus preparation	Manus preparation	-	-	NO
550646	15717931	WWW	1	Concepts and supervision	Concepts and supervision	Conceived and designed the experiments	Conceptualization|Supervision	YES
550646	15717931	YM	1	Assays and rflp assays|Luciferase expression	Assays and rflp assays	Performed the experiments	Investigation	YES
550646	15717931	YM	1	Assays and rflp assays|Luciferase expression	Luciferase expression	Performed the experiments	Investigation	YES
5915650	29661978	All the authors	2	gave their final approval for publication	gave their final approval for publication	-	-	NO
5915650	29661978	F.H.	2	helped draft the manuscript	helped draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5915650	29661978	F.M.	2	performed biofilm work and helped in statistical analysis	performed biofilm work and helped in statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5915650	29661978	M.J.D.	2	helped draft the manuscript	helped draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5915650	29661978	M.T.	2	performed qrt-pcr gene expression in 2d and 3d nanovibrational stimulation	performed qrt-pcr gene expression in 2d and 3d nanovibrational stimulation	Performed the experiments	Investigation	YES
5915650	29661978	P.C.	2	performed interferometry and helped draft the manuscript	performed interferometry and helped draft the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5915650	29661978	P.G.C.	2	helped draft the manuscript	helped draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5915650	29661978	S.N.R.	2	drafted the manuscript, participated in design of the bacterial biofilm study and statistical data analysis of study	drafted the manuscript, participated in design of the bacterial biofilm study and statistical data analysis of study	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5915650	29661978	S.R.	2	helped draft the manuscript	helped draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5915650	29661978	Von Kossa	2	staining and relevant statistical analysis	staining and relevant statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3492075	23021076	The authors	2	declare that we belong to a group of researcher with common interest on research	declare that we belong to a group of researcher with common interest on research	-	-	NO
3705783	23864860	Kumiko Terada	PLoS52	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3705783	23864860	Satomi Misao	PLoS52	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3705783	23864860	Tsutomu Nohno	PLoS52	conceived and designed the experiments|prepared the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
3705783	23864860	Tsutomu Nohno	PLoS52	conceived and designed the experiments|prepared the paper	prepared the paper	Wrote the paper	Writing - Original Draft	YES
4411105	25915526	BR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411105	25915526	BR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411105	25915526	BR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411105	25915526	GG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411105	25915526	GG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411105	25915526	GG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411105	25915526	GS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411105	25915526	GS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411105	25915526	GS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411105	25915526	GS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411105	25915526	IM	PLoS5	Did the clinical assessments|Contributed to the studys database	Did the clinical assessments	-	-	NO
4411105	25915526	IM	PLoS5	Did the clinical assessments|Contributed to the studys database	Contributed to the studys database	Contributed reagents/materials/analysis tools	Resources|Software	YES
4411105	25915526	JMH	PLoS5	Implemented the clinical protocol	Implemented the clinical protocol	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4411105	25915526	MF	PLoS5	Performed the experiments|Analyzed the data|Implemented the clinical protocol|Contributed to the studys database	Performed the experiments	Performed the experiments	Investigation	YES
4411105	25915526	MF	PLoS5	Performed the experiments|Analyzed the data|Implemented the clinical protocol|Contributed to the studys database	Analyzed the data	Analyzed the data	Formal analysis	YES
4411105	25915526	MF	PLoS5	Performed the experiments|Analyzed the data|Implemented the clinical protocol|Contributed to the studys database	Implemented the clinical protocol	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4411105	25915526	MF	PLoS5	Performed the experiments|Analyzed the data|Implemented the clinical protocol|Contributed to the studys database	Contributed to the studys database	Contributed reagents/materials/analysis tools	Resources|Software	YES
4411105	25915526	RP	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Contributed to the studys database	Performed the experiments	Performed the experiments	Investigation	YES
4411105	25915526	RP	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Contributed to the studys database	Analyzed the data	Analyzed the data	Formal analysis	YES
4411105	25915526	RP	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Contributed to the studys database	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411105	25915526	RP	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Contributed to the studys database	Contributed to the studys database	Contributed reagents/materials/analysis tools	Resources|Software	YES
4411105	25915526	VVG	PLoS5	Implemented the clinical protocol|Contributed to the studys database	Implemented the clinical protocol	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4411105	25915526	VVG	PLoS5	Implemented the clinical protocol|Contributed to the studys database	Contributed to the studys database	Contributed reagents/materials/analysis tools	Resources|Software	YES
1824711	17389914	AL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1824711	17389914	AL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1824711	17389914	AL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1824711	17389914	AL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1824711	17389914	MO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1824711	17389914	MO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1824711	17389914	MO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1824711	17389914	MO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1824711	17389914	PB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1824711	17389914	PB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1824711	17389914	PB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1824711	17389914	YH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
6462809	30983148	A.G.	PLoS52	conceptualized and designed the study, and had primary responsibility for interpretation of the data	conceptualized and designed the study, and had primary responsibility for interpretation of the data	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
6462809	30983148	A.K.	PLoS52	analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
6462809	30983148	B.L.G.	PLoS52	conceptualized and designed the study, and had primary responsibility for interpretation of the data	conceptualized and designed the study, and had primary responsibility for interpretation of the data	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
6462809	30983148	B.M.	PLoS52	analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
6462809	30983148	E.A.	PLoS52	conceptualized and designed the study, and had primary responsibility for interpretation of the data	conceptualized and designed the study, and had primary responsibility for interpretation of the data	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
6462809	30983148	J.M.H.	PLoS52	conceptualized and designed the study, and had primary responsibility for interpretation of the data	conceptualized and designed the study, and had primary responsibility for interpretation of the data	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
6462809	30983148	J.W.H.	PLoS52	conceptualized and designed the study, and had primary responsibility for interpretation of the data	conceptualized and designed the study, and had primary responsibility for interpretation of the data	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
6462809	30983148	K.W.	PLoS52	conceptualized and designed the study, and had primary responsibility for interpretation of the data	conceptualized and designed the study, and had primary responsibility for interpretation of the data	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
5938633	29712793	All authors	2	contributed to the methodological design, analysis and interpretation of data, and drafting of the manuscript	contributed to the methodological design, analysis and interpretation of data, and drafting of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Original Draft	YES
5938633	29712793	R.J.D.	2	coordinated this work and led the drafting of the manuscript	coordinated this work and led the drafting of the manuscript	Wrote the paper	Project administration|Writing - Original Draft	YES
550655	15717932	OD	2	conceived of the study and participated in the sequences alignment	conceived of the study and participated in the sequences alignment	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
550655	15717932	TV	2	coordinated the study	coordinated the study	-	Project administration	YES
4411106	25915401	AMN	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411106	25915401	AMN	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411106	25915401	AMN	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411106	25915401	JSP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411106	25915401	JSP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411106	25915401	JSP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411106	25915401	JSP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411106	25915401	SH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411106	25915401	SH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411106	25915401	SH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411106	25915401	SH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411106	25915401	SK	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5670114	29163572	AC	2	isolated bacteria from root samples, extracted rhizobacterial dna, and prepared it for sequencing|analyzed microbial community sequences|conducted root and microbial enzyme analysis	isolated bacteria from root samples, extracted rhizobacterial dna, and prepared it for sequencing	Performed the experiments	Investigation	YES
5670114	29163572	AC	2	isolated bacteria from root samples, extracted rhizobacterial dna, and prepared it for sequencing|analyzed microbial community sequences|conducted root and microbial enzyme analysis	analyzed microbial community sequences	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5670114	29163572	AC	2	isolated bacteria from root samples, extracted rhizobacterial dna, and prepared it for sequencing|analyzed microbial community sequences|conducted root and microbial enzyme analysis	conducted root and microbial enzyme analysis	Performed the experiments	Investigation	YES
5670114	29163572	All authors	2	contributed to writing and finalizing the paper, and also read and approved the final manuscript	contributed to writing and finalizing the paper, and also read and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5670114	29163572	CT	2	isolated bacteria from root samples, extracted rhizobacterial dna, and prepared it for sequencing|analyzed microbial community sequences|conducted root and microbial enzyme analysis	isolated bacteria from root samples, extracted rhizobacterial dna, and prepared it for sequencing	Performed the experiments	Investigation	YES
5670114	29163572	CT	2	isolated bacteria from root samples, extracted rhizobacterial dna, and prepared it for sequencing|analyzed microbial community sequences|conducted root and microbial enzyme analysis	analyzed microbial community sequences	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5670114	29163572	CT	2	isolated bacteria from root samples, extracted rhizobacterial dna, and prepared it for sequencing|analyzed microbial community sequences|conducted root and microbial enzyme analysis	conducted root and microbial enzyme analysis	Performed the experiments	Investigation	YES
5670114	29163572	DP	2	isolated bacteria from root samples, extracted rhizobacterial dna, and prepared it for sequencing	isolated bacteria from root samples, extracted rhizobacterial dna, and prepared it for sequencing	Performed the experiments	Investigation	YES
5670114	29163572	DW	2	designed the study|isolated bacteria from root samples, extracted rhizobacterial dna, and prepared it for sequencing|analyzed microbial community sequences	designed the study	Conceived and designed the experiments	Methodology	YES
5670114	29163572	DW	2	designed the study|isolated bacteria from root samples, extracted rhizobacterial dna, and prepared it for sequencing|analyzed microbial community sequences	isolated bacteria from root samples, extracted rhizobacterial dna, and prepared it for sequencing	Performed the experiments	Investigation	YES
5670114	29163572	DW	2	designed the study|isolated bacteria from root samples, extracted rhizobacterial dna, and prepared it for sequencing|analyzed microbial community sequences	analyzed microbial community sequences	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5670114	29163572	JC	2	conducted the field studies|performed the p analysis	conducted the field studies	Performed the experiments	Investigation	YES
5670114	29163572	JC	2	conducted the field studies|performed the p analysis	performed the p analysis	Performed the experiments	Investigation	YES
5670114	29163572	KC	2	designed the study|conducted the field studies|isolated bacteria from root samples, extracted rhizobacterial dna, and prepared it for sequencing|analyzed microbial community sequences|conducted root and microbial enzyme analysis|drafted the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5670114	29163572	KC	2	designed the study|conducted the field studies|isolated bacteria from root samples, extracted rhizobacterial dna, and prepared it for sequencing|analyzed microbial community sequences|conducted root and microbial enzyme analysis|drafted the manuscript	conducted the field studies	Performed the experiments	Investigation	YES
5670114	29163572	KC	2	designed the study|conducted the field studies|isolated bacteria from root samples, extracted rhizobacterial dna, and prepared it for sequencing|analyzed microbial community sequences|conducted root and microbial enzyme analysis|drafted the manuscript	isolated bacteria from root samples, extracted rhizobacterial dna, and prepared it for sequencing	Performed the experiments	Investigation	YES
5670114	29163572	KC	2	designed the study|conducted the field studies|isolated bacteria from root samples, extracted rhizobacterial dna, and prepared it for sequencing|analyzed microbial community sequences|conducted root and microbial enzyme analysis|drafted the manuscript	analyzed microbial community sequences	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5670114	29163572	KC	2	designed the study|conducted the field studies|isolated bacteria from root samples, extracted rhizobacterial dna, and prepared it for sequencing|analyzed microbial community sequences|conducted root and microbial enzyme analysis|drafted the manuscript	conducted root and microbial enzyme analysis	Performed the experiments	Investigation	YES
5670114	29163572	KC	2	designed the study|conducted the field studies|isolated bacteria from root samples, extracted rhizobacterial dna, and prepared it for sequencing|analyzed microbial community sequences|conducted root and microbial enzyme analysis|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5670114	29163572	RN	2	designed the study|conducted the field studies	designed the study	Conceived and designed the experiments	Methodology	YES
5670114	29163572	RN	2	designed the study|conducted the field studies	conducted the field studies	Performed the experiments	Investigation	YES
5670114	29163572	T-YL	2	isolated bacteria from root samples, extracted rhizobacterial dna, and prepared it for sequencing	isolated bacteria from root samples, extracted rhizobacterial dna, and prepared it for sequencing	Performed the experiments	Investigation	YES
1828616	17389916	DH	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1828616	17389916	DH	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1828616	17389916	XM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1828616	17389916	XM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1828616	17389916	XM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1828616	17389916	XM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5938637	29712797	All	2	the co-authors have contributed to different parts of the manuscript, in particular ssss1 and 2	the co-authors have contributed to different parts of the manuscript, in particular ssss1 and 2	-	-	NO
5938637	29712797	E.F.	2	has contributed to estimating some aggregated indices	has contributed to estimating some aggregated indices	Analyzed the data	Formal analysis	YES
5938637	29712797	F.B.	2	have contributed to the conceptual design of the study and summarizing the results	have contributed to the conceptual design of the study and summarizing the results	Conceived and designed the experiments	Conceptualization|Methodology	YES
5938637	29712797	J.M.	2	have computed the indices and calculated the index	have computed the indices and calculated the index	Analyzed the data	Formal analysis	YES
5938637	29712797	M.A.	2	have computed the indices and calculated the index	have computed the indices and calculated the index	Analyzed the data	Formal analysis	YES
5938637	29712797	M.M.	2	have computed the indices and calculated the index	have computed the indices and calculated the index	Analyzed the data	Formal analysis	YES
5938637	29712797	S.T.	2	have contributed to the conceptual design of the study and summarizing the results	have contributed to the conceptual design of the study and summarizing the results	Conceived and designed the experiments	Conceptualization|Methodology	YES
3502275	23067582	AG	PLoS52	designed the primer and helped in cloning experiment	designed the primer and helped in cloning experiment	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3502275	23067582	GJ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
3502275	23067582	PR	PLoS52	designed the experiments, analyzed the results and drafted the manuscript	designed the experiments, analyzed the results and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3502275	23067582	RT	PLoS52	provided help in developing the recombinant protein	provided help in developing the recombinant protein	Performed the experiments	Investigation	YES
3502275	23067582	SKP	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
1828617	17389917	CW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1828617	17389917	CW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1828617	17389917	CW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1828617	17389917	RB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1828617	17389917	RB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1828617	17389917	RB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6462810	30983111	All	2	six authors meet criteria for authorship and have made substantial contributions to various facets of the study including study design, data collection and analysis, and writing and editing of the manuscript|six authors take responsibility for the reported research, have critically reviewed this final manuscript, approved its submission and take full responsibility for the manuscript	six authors meet criteria for authorship and have made substantial contributions to various facets of the study including study design, data collection and analysis, and writing and editing of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
6462810	30983111	All	2	six authors meet criteria for authorship and have made substantial contributions to various facets of the study including study design, data collection and analysis, and writing and editing of the manuscript|six authors take responsibility for the reported research, have critically reviewed this final manuscript, approved its submission and take full responsibility for the manuscript	six authors take responsibility for the reported research, have critically reviewed this final manuscript, approved its submission and take full responsibility for the manuscript	Wrote the paper	Writing - Review & Editing	YES
6462810	30983111	HIV	2	exposure respectively	exposure respectively	-	-	NO
6462810	30983111	KB	2	reviewed all articles and performed data collection	reviewed all articles and performed data collection	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
6462810	30983111	MM	2	first conceptualized this systematic review|reviewed all articles and performed data collection|wrote the first draft with considerable input from the coauthors	first conceptualized this systematic review	Conceived and designed the experiments	Conceptualization	YES
6462810	30983111	MM	2	first conceptualized this systematic review|reviewed all articles and performed data collection|wrote the first draft with considerable input from the coauthors	reviewed all articles and performed data collection	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
6462810	30983111	MM	2	first conceptualized this systematic review|reviewed all articles and performed data collection|wrote the first draft with considerable input from the coauthors	wrote the first draft with considerable input from the coauthors	Wrote the paper	Writing - Original Draft	YES
4411107	25915936	CHW	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411107	25915936	CHW	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411107	25915936	CHW	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411107	25915936	CLY	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411107	25915936	CLY	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411107	25915936	CLY	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411107	25915936	CLY	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411107	25915936	CYT	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411107	25915936	CYT	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4411107	25915936	KJL	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4411107	25915936	KJL	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4411107	25915936	SCH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411107	25915936	SCH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411107	25915936	SCH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5954464	29760108	A.M.	2	conducted the oxygen isotope measurements	conducted the oxygen isotope measurements	Performed the experiments	Investigation	YES
5954464	29760108	A.V.B.	2	designed and implemented the sampling programme and initial sample/data handling	designed and implemented the sampling programme and initial sample/data handling	Conceived and designed the experiments|Performed the experiments	Data curation|Investigation	YES
5954464	29760108	All authors	2	contributed to the interpretation and discussion of the results, and approved the final version of the paper	contributed to the interpretation and discussion of the results, and approved the final version of the paper	Analyzed the data	Formal analysis	YES
5954464	29760108	E.R.B.	2	designed and implemented the sampling programme and initial sample/data handling	designed and implemented the sampling programme and initial sample/data handling	Conceived and designed the experiments|Performed the experiments	Data curation|Investigation	YES
5954464	29760108	M.M.	2	led the data analysis/interpretation and the writing of the paper	led the data analysis/interpretation and the writing of the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5954464	29760108	U.F.	2	processed the meteorological data and conducted the glacial discharge simulations	processed the meteorological data and conducted the glacial discharge simulations	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5670151	29163588	AF	2	performed the data analysis and revised the paper	performed the data analysis and revised the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5670151	29163588	AT	2	carried out the data analyses and wrote the manuscript	carried out the data analyses and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5670151	29163588	AnV	2	carried out the data analyses and wrote the manuscript|performed the data analysis and revised the paper	carried out the data analyses and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5670151	29163588	AnV	2	carried out the data analyses and wrote the manuscript|performed the data analysis and revised the paper	performed the data analysis and revised the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5670151	29163588	CB	2	carried out the data analyses and wrote the manuscript|participated in field and post-harvest evaluations of phenotypic traits	carried out the data analyses and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5670151	29163588	CB	2	carried out the data analyses and wrote the manuscript|participated in field and post-harvest evaluations of phenotypic traits	participated in field and post-harvest evaluations of phenotypic traits	Performed the experiments	Investigation	YES
5670151	29163588	DC	2	participated in field and post-harvest evaluations of phenotypic traits	participated in field and post-harvest evaluations of phenotypic traits	Performed the experiments	Investigation	YES
5670151	29163588	FB	2	performed the data analysis and revised the paper	performed the data analysis and revised the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5670151	29163588	FD	2	carried out the data analyses and wrote the manuscript|participated in field and post-harvest evaluations of phenotypic traits|performed the data analysis and revised the paper	carried out the data analyses and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5670151	29163588	FD	2	carried out the data analyses and wrote the manuscript|participated in field and post-harvest evaluations of phenotypic traits|performed the data analysis and revised the paper	participated in field and post-harvest evaluations of phenotypic traits	Performed the experiments	Investigation	YES
5670151	29163588	FD	2	carried out the data analyses and wrote the manuscript|participated in field and post-harvest evaluations of phenotypic traits|performed the data analysis and revised the paper	performed the data analysis and revised the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5670151	29163588	GO	2	participated in field and post-harvest evaluations of phenotypic traits	participated in field and post-harvest evaluations of phenotypic traits	Performed the experiments	Investigation	YES
5670151	29163588	GS	2	designed the study and revised the paper	designed the study and revised the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5670151	29163588	GV	2	designed the study and revised the paper	designed the study and revised the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5670151	29163588	LC	2	designed the study and revised the paper	designed the study and revised the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5670151	29163588	MBH	2	participated in field and post-harvest evaluations of phenotypic traits	participated in field and post-harvest evaluations of phenotypic traits	Performed the experiments	Investigation	YES
5670151	29163588	PC	2	performed the data analysis and revised the paper	performed the data analysis and revised the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5670151	29163588	PP	2	designed the study and revised the paper	designed the study and revised the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5670151	29163588	PR	2	participated in field and post-harvest evaluations of phenotypic traits	participated in field and post-harvest evaluations of phenotypic traits	Performed the experiments	Investigation	YES
5670151	29163588	RP	2	participated in field and post-harvest evaluations of phenotypic traits	participated in field and post-harvest evaluations of phenotypic traits	Performed the experiments	Investigation	YES
5670151	29163588	SU	2	participated in field and post-harvest evaluations of phenotypic traits	participated in field and post-harvest evaluations of phenotypic traits	Performed the experiments	Investigation	YES
550658	15720707	JY	2	did wet-lab testing of a subset of primer pairs	did wet-lab testing of a subset of primer pairs	Performed the experiments	Investigation	YES
550658	15720707	MES	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
550658	15720707	ML	2	did all programming and design of computational experiments and databases|drafted the manuscript	did all programming and design of computational experiments and databases	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Methodology|Software	YES
550658	15720707	ML	2	did all programming and design of computational experiments and databases|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
550658	15720707	RVK	2	contributed in the first database design	contributed in the first database design	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Resources|Software	YES
1828618	17396164	EK	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1828618	17396164	EK	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1828618	17396164	NN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1828618	17396164	NN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1828618	17396164	NN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1828618	17396164	NN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1828618	17396164	NN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1828618	17396164	SK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1828618	17396164	SK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1828618	17396164	SK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411108	25915515	HW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411108	25915515	HW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411108	25915515	HW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411108	25915515	HW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411108	25915515	HW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411108	25915515	LJ	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411108	25915515	LJ	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411108	25915515	QW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411108	25915515	QW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411108	25915515	QW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411108	25915515	YC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411108	25915515	YL	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411108	25915515	YZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
3742022	23997768	H. Benzin	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
3742022	23997768	S. Danner	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
4411109	25915767	FP	PLoS5	Performed the experiments|Provided access to the database|Contributed to the design of software for analysis and graphical presentation	Performed the experiments	Performed the experiments	Investigation	YES
4411109	25915767	FP	PLoS5	Performed the experiments|Provided access to the database|Contributed to the design of software for analysis and graphical presentation	Provided access to the database	Contributed reagents/materials/analysis tools	Resources|Software	YES
4411109	25915767	FP	PLoS5	Performed the experiments|Provided access to the database|Contributed to the design of software for analysis and graphical presentation	Contributed to the design of software for analysis and graphical presentation	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
4411109	25915767	MB	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411109	25915767	NB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411109	25915767	NB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411109	25915767	NB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411109	25915767	NB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5506605	28697743	CC	2	wrote the manuscript, with input from all authors|supervised the research	wrote the manuscript, with input from all authors	Wrote the paper	Writing - Original Draft	YES
5506605	28697743	CC	2	wrote the manuscript, with input from all authors|supervised the research	supervised the research	-	Supervision	YES
5506605	28697743	HME	2	wrote the manuscript, with input from all authors|supervised the research	wrote the manuscript, with input from all authors	Wrote the paper	Writing - Original Draft	YES
5506605	28697743	HME	2	wrote the manuscript, with input from all authors|supervised the research	supervised the research	-	Supervision	YES
5506605	28697743	JC	2	contributed samples and data	contributed samples and data	Contributed reagents/materials/analysis tools	Resources	YES
5506605	28697743	JE	2	contributed samples and data|wrote the manuscript, with input from all authors	contributed samples and data	Contributed reagents/materials/analysis tools	Resources	YES
5506605	28697743	JE	2	contributed samples and data|wrote the manuscript, with input from all authors	wrote the manuscript, with input from all authors	Wrote the paper	Writing - Original Draft	YES
5506605	28697743	MI	2	designed and performed the experiments|performed data analysis|wrote the manuscript, with input from all authors	designed and performed the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5506605	28697743	MI	2	designed and performed the experiments|performed data analysis|wrote the manuscript, with input from all authors	performed data analysis	Analyzed the data	Formal analysis	YES
5506605	28697743	MI	2	designed and performed the experiments|performed data analysis|wrote the manuscript, with input from all authors	wrote the manuscript, with input from all authors	Wrote the paper	Writing - Original Draft	YES
5506605	28697743	OE	2	contributed samples and data|wrote the manuscript, with input from all authors	contributed samples and data	Contributed reagents/materials/analysis tools	Resources	YES
5506605	28697743	OE	2	contributed samples and data|wrote the manuscript, with input from all authors	wrote the manuscript, with input from all authors	Wrote the paper	Writing - Original Draft	YES
5506605	28697743	OR	2	performed data analysis|wrote the manuscript, with input from all authors	performed data analysis	Analyzed the data	Formal analysis	YES
5506605	28697743	OR	2	performed data analysis|wrote the manuscript, with input from all authors	wrote the manuscript, with input from all authors	Wrote the paper	Writing - Original Draft	YES
6466898	30990252	AX	2	provided critical revisions of the manuscript	provided critical revisions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
6466898	30990252	EBM	2	provided critical revisions of the manuscript	provided critical revisions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
6466898	30990252	EPH	2	designed the study|wrote the first draft of the manuscript|provided critical revisions of the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
6466898	30990252	EPH	2	designed the study|wrote the first draft of the manuscript|provided critical revisions of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
6466898	30990252	EPH	2	designed the study|wrote the first draft of the manuscript|provided critical revisions of the manuscript	provided critical revisions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
6466898	30990252	KM	2	designed the study|provided critical revisions of the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
6466898	30990252	KM	2	designed the study|provided critical revisions of the manuscript	provided critical revisions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
6466898	30990252	LGB	2	provided critical revisions of the manuscript	provided critical revisions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
6466898	30990252	MH	2	provided critical revisions of the manuscript	provided critical revisions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
6466898	30990252	RAP	2	designed the study|provided critical revisions of the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
6466898	30990252	RAP	2	designed the study|provided critical revisions of the manuscript	provided critical revisions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
6466898	30990252	RPW	2	provided critical revisions of the manuscript	provided critical revisions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5670326	29163587	AM	2	contributed to the design of the research project	contributed to the design of the research project	Conceived and designed the experiments	Methodology	YES
5670326	29163587	CC	2	contributed to the design of the research project, site selection and collection of material	contributed to the design of the research project, site selection and collection of material	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources	YES
5670326	29163587	CL	2	contributed to the design of the research project, data analysis and drafted the manuscript	contributed to the design of the research project, data analysis and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Original Draft	YES
5670326	29163587	HX	2	carried out the experiments and contributed to data analysis	carried out the experiments and contributed to data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5670326	29163587	JB	2	contributed to the design of the research project	contributed to the design of the research project	Conceived and designed the experiments	Methodology	YES
5670326	29163587	JS	2	contributed to the design of the research project	contributed to the design of the research project	Conceived and designed the experiments	Methodology	YES
5670326	29163587	KT	2	performed tassel analysis on msgbs data	performed tassel analysis on msgbs data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5670326	29163587	MG	2	contributed to the design of the research project	contributed to the design of the research project	Conceived and designed the experiments	Methodology	YES
5670326	29163587	MK	2	carried out the experiments and contributed to data analysis	carried out the experiments and contributed to data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5670326	29163587	NS	2	performed gene ontology analysis on msgbs data	performed gene ontology analysis on msgbs data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5670326	29163587	RDB	2	contributed to the design of the research project, site selection and collection of material	contributed to the design of the research project, site selection and collection of material	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources	YES
5670326	29163587	TC	2	contributed to the design of the research project	contributed to the design of the research project	Conceived and designed the experiments	Methodology	YES
5954465	29760109	Both authors	2	contributed to the design and drafting of the manuscript	contributed to the design and drafting of the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
1828619	17396165	BL	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1828619	17396165	BL	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1828619	17396165	CS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1828619	17396165	CS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1828619	17396165	DG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1828619	17396165	DG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1828619	17396165	DG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1828619	17396165	DG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1828619	17396165	DG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1828619	17396165	EC	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1828619	17396165	EC	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1828619	17396165	EC	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1828619	17396165	NB	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1828619	17396165	NB	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1828619	17396165	RL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1828619	17396165	RL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1828619	17396165	RL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1828619	17396165	RS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1828619	17396165	RS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1828619	17396165	SG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1828619	17396165	SG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1828619	17396165	SG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1828619	17396165	SW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1828619	17396165	SW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1828619	17396165	SW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1828619	17396165	SW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1828619	17396165	TH	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1828619	17396165	TH	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1828619	17396165	YS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1828619	17396165	YS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1828619	17396165	YS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1828619	17396165	YS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
3519684	22812483	All	2	this work was carried out under the supervision of ark who conceived and coordinated the study, designed the experiments and drafted the manuscript	this work was carried out under the supervision of ark who conceived and coordinated the study, designed the experiments and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Project administration|Supervision|Writing - Original Draft	YES
3519684	22812483	CJ	2	carried out the experiments on the wastes	carried out the experiments on the wastes	Performed the experiments	Investigation	YES
3519684	22812483	SSZ	2	helped to draft the manuscript	helped to draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5941283	29780546	All authors	2	have given approval to the final version of the manuscript	have given approval to the final version of the manuscript	-	-	NO
4411110	25915660	AI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411110	25915660	AI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411110	25915660	AI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411110	25915660	AI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411110	25915660	CY	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411110	25915660	CY	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411110	25915660	DV	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411110	25915660	DV	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411110	25915660	HS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411110	25915660	NP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411110	25915660	NP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411110	25915660	NP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411110	25915660	NP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411110	25915660	TD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411110	25915660	TD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411110	25915660	TD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411110	25915660	TD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411110	25915660	TM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411110	25915660	TM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411110	25915660	TM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411110	25915660	TM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3519744	23009357	JN	2	participated in the design of the study|supervised the project and edited manuscript	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
3519744	23009357	JN	2	participated in the design of the study|supervised the project and edited manuscript	supervised the project and edited manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
3519744	23009357	KK	2	participated in the design of the study|performed the experimental work, analyzed the data and wrote the manuscript	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
3519744	23009357	KK	2	participated in the design of the study|performed the experimental work, analyzed the data and wrote the manuscript	performed the experimental work, analyzed the data and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3519744	23009357	VS	2	supervised the project and edited manuscript	supervised the project and edited manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
3519744	23009357	YC	2	contributed the plasmid, piyc08, used in this study	contributed the plasmid, piyc08, used in this study	Performed the experiments	Investigation	YES
5508667	28705154	AN	PLoS52	conceived and designed the study|drafted the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5508667	28705154	AN	PLoS52	conceived and designed the study|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5508667	28705154	All authors	PLoS52	contributed and approved the final version of the manuscript	contributed and approved the final version of the manuscript	-	-	NO
5508667	28705154	BG	PLoS52	conceived and designed the study|drafted the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5508667	28705154	BG	PLoS52	conceived and designed the study|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5508667	28705154	MC	PLoS52	set-up the experiments regarding bacterial cultivation, genomic dna extraction and rezasurin assay|performed the experiments	set-up the experiments regarding bacterial cultivation, genomic dna extraction and rezasurin assay	Performed the experiments	Investigation	YES
5508667	28705154	MC	PLoS52	set-up the experiments regarding bacterial cultivation, genomic dna extraction and rezasurin assay|performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5508667	28705154	PC	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5508667	28705154	SFR	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
6467461	30990969	CP	2	contributed to the study concept and design	contributed to the study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6467461	30990969	JA	2	contributed to the study concept and design	contributed to the study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6467461	30990969	JS	2	were the study coordinator	were the study coordinator	-	Project administration	YES
6467461	30990969	KM	2	contributed to the study concept and design|contributed to analysis and interpretation of the data	contributed to the study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6467461	30990969	KM	2	contributed to the study concept and design|contributed to analysis and interpretation of the data	contributed to analysis and interpretation of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6467461	30990969	MV	2	contributed to the study concept and design	contributed to the study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6467461	30990969	NJ	2	contributed to the study concept and design	contributed to the study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6467461	30990969	PT	2	contributed to the study concept and design	contributed to the study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6467461	30990969	SP	2	was statisticians	was statisticians	Analyzed the data	Formal analysis	YES
6467461	30990969	TP	2	contributed to the study concept and design|contributed to analysis and interpretation of the data	contributed to the study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6467461	30990969	TP	2	contributed to the study concept and design|contributed to analysis and interpretation of the data	contributed to analysis and interpretation of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6467461	30990969	TT	2	were the study coordinator	were the study coordinator	-	Project administration	YES
6467461	30990969	WC	2	contributed to the study concept and design|contributed to analysis and interpretation of the data	contributed to the study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6467461	30990969	WC	2	contributed to the study concept and design|contributed to analysis and interpretation of the data	contributed to analysis and interpretation of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6467461	30990969	WJ	2	contributed to the study concept and design|contributed to analysis and interpretation of the data|wrote the first draft of the paper and all co-authors contributed to interpreting the findings and revised the manuscript	contributed to the study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6467461	30990969	WJ	2	contributed to the study concept and design|contributed to analysis and interpretation of the data|wrote the first draft of the paper and all co-authors contributed to interpreting the findings and revised the manuscript	contributed to analysis and interpretation of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6467461	30990969	WJ	2	contributed to the study concept and design|contributed to analysis and interpretation of the data|wrote the first draft of the paper and all co-authors contributed to interpreting the findings and revised the manuscript	wrote the first draft of the paper and all co-authors contributed to interpreting the findings and revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5670350	29163594	All authors	2	took part in analyzing the data and approved the manuscript	took part in analyzing the data and approved the manuscript	Analyzed the data	Formal analysis	YES
5670350	29163594	CL	2	determined the aroma compound contents	determined the aroma compound contents	Performed the experiments	Investigation	YES
5670350	29163594	CW	2	conceived and designed the research|provided technical guidance and supervised the writing	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5670350	29163594	CW	2	conceived and designed the research|provided technical guidance and supervised the writing	provided technical guidance and supervised the writing	Wrote the paper	Supervision	YES
5670350	29163594	HD	2	analyzed the transcriptome sequences and tested the gene expressions	analyzed the transcriptome sequences and tested the gene expressions	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5670350	29163594	JG	2	provided technical guidance and supervised the writing	provided technical guidance and supervised the writing	Wrote the paper	Supervision	YES
5670350	29163594	JL	2	provided technical guidance and supervised the writing	provided technical guidance and supervised the writing	Wrote the paper	Supervision	YES
5670350	29163594	RZ	2	conceived and designed the research|determined the aroma compound contents|analyzed the transcriptome sequences and tested the gene expressions|wrote the manuscript	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5670350	29163594	RZ	2	conceived and designed the research|determined the aroma compound contents|analyzed the transcriptome sequences and tested the gene expressions|wrote the manuscript	determined the aroma compound contents	Performed the experiments	Investigation	YES
5670350	29163594	RZ	2	conceived and designed the research|determined the aroma compound contents|analyzed the transcriptome sequences and tested the gene expressions|wrote the manuscript	analyzed the transcriptome sequences and tested the gene expressions	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5670350	29163594	RZ	2	conceived and designed the research|determined the aroma compound contents|analyzed the transcriptome sequences and tested the gene expressions|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5670350	29163594	WX	2	determined the aroma compound contents	determined the aroma compound contents	Performed the experiments	Investigation	YES
5670350	29163594	XZ	2	analyzed the transcriptome sequences and tested the gene expressions	analyzed the transcriptome sequences and tested the gene expressions	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5670350	29163594	YW	2	determined the aroma compound contents|analyzed the transcriptome sequences and tested the gene expressions	determined the aroma compound contents	Performed the experiments	Investigation	YES
5670350	29163594	YW	2	determined the aroma compound contents|analyzed the transcriptome sequences and tested the gene expressions	analyzed the transcriptome sequences and tested the gene expressions	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
1828620	17389918	AB	PLoS5	Revised the paper	Revised the paper	Wrote the paper	Writing - Review & Editing	YES
1828620	17389918	AC	PLoS5	Contributed reagents/materials/analysis tools|Revised the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1828620	17389918	AC	PLoS5	Contributed reagents/materials/analysis tools|Revised the paper	Revised the paper	Wrote the paper	Writing - Review & Editing	YES
1828620	17389918	AP	PLoS5	Analyzed the data|Revised the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1828620	17389918	AP	PLoS5	Analyzed the data|Revised the paper	Revised the paper	Wrote the paper	Writing - Review & Editing	YES
1828620	17389918	CB	PLoS5	Revised the paper	Revised the paper	Wrote the paper	Writing - Review & Editing	YES
1828620	17389918	CS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1828620	17389918	CS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1828620	17389918	CS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1828620	17389918	JL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Revised the paper	Performed the experiments	Performed the experiments	Investigation	YES
1828620	17389918	JL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Revised the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1828620	17389918	JL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Revised the paper	Revised the paper	Wrote the paper	Writing - Review & Editing	YES
1828620	17389918	MC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1828620	17389918	PS	PLoS5	Contributed reagents/materials/analysis tools|Revised the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1828620	17389918	PS	PLoS5	Contributed reagents/materials/analysis tools|Revised the paper	Revised the paper	Wrote the paper	Writing - Review & Editing	YES
1828620	17389918	PW	PLoS5	Analyzed the data|Revised the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1828620	17389918	PW	PLoS5	Analyzed the data|Revised the paper	Revised the paper	Wrote the paper	Writing - Review & Editing	YES
1828620	17389918	SC	PLoS5	Conceived and designed the experiments|Analyzed the data|Oversaw the operation and accuracy of the entire study	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1828620	17389918	SC	PLoS5	Conceived and designed the experiments|Analyzed the data|Oversaw the operation and accuracy of the entire study	Analyzed the data	Analyzed the data	Formal analysis	YES
1828620	17389918	SC	PLoS5	Conceived and designed the experiments|Analyzed the data|Oversaw the operation and accuracy of the entire study	Oversaw the operation and accuracy of the entire study	Performed the experiments	Investigation|Supervision	YES
1828620	17389918	SY	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1828620	17389918	TS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1828620	17389918	WW	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1828620	17389918	XL	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1828620	17389918	XL	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1828620	17389918	ZO	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411111	25915922	JMA	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411111	25915922	MRP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411111	25915922	MRP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411111	25915922	MRP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411111	25915922	SH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411111	25915922	SH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411111	25915922	SH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411111	25915922	SH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5954468	29760112	E.M.J.	2	produced the carbonate system data and helped to write the manuscript	produced the carbonate system data and helped to write the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5954468	29760112	H.J.V.	2	produced the physical oceanographic data and helped to write the manuscript	produced the physical oceanographic data and helped to write the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5954468	29760112	J.D.	2	assisted in collecting and interpreting the isotope data and drafting the manuscript	assisted in collecting and interpreting the isotope data and drafting the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5954468	29760112	J.S.	2	assisted in designing the study, collecting biogeochemical data and drafting the manuscript	assisted in designing the study, collecting biogeochemical data and drafting the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5954468	29760112	M.P.M.	2	produced the seawater oxygen isotope data and helped to write the manuscript	produced the seawater oxygen isotope data and helped to write the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5954468	29760112	R.D.	2	assisted in producing the nutrient isotope data and writing the manuscript	assisted in producing the nutrient isotope data and writing the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5954468	29760112	S.F.H.	2	designed and led the study, produced the nutrient and nutrient isotope data and wrote the manuscript	designed and led the study, produced the nutrient and nutrient isotope data and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5954468	29760112	S.H.	2	assisted in collecting biogeochemical data and writing the manuscript	assisted in collecting biogeochemical data and writing the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5954468	29760112	Y.L.F.	2	assisted in collecting and processing the physics data and writing the manuscript	assisted in collecting and processing the physics data and writing the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Investigation|Writing - Original Draft	YES
1828621	17389919	BL	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1828621	17389919	BL	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1828621	17389919	DR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1828621	17389919	DR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1828621	17389919	DR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1828621	17389919	LB	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1828621	17389919	LB	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1828621	17389919	LE	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1828621	17389919	LE	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1828621	17389919	MS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1828621	17389919	MS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1828621	17389919	MS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3534607	23092441	AN	2	participated in the design of this study|performed the experimental work, analyzed the data, and drafted the manuscript	participated in the design of this study	Conceived and designed the experiments	Methodology	YES
3534607	23092441	AN	2	participated in the design of this study|performed the experimental work, analyzed the data, and drafted the manuscript	performed the experimental work, analyzed the data, and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3534607	23092441	JB	2	performed the experimental work, analyzed the data, and drafted the manuscript	performed the experimental work, analyzed the data, and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3534607	23092441	KK	2	participated in the design of this study|supervised this study and edited manuscript	participated in the design of this study	Conceived and designed the experiments	Methodology	YES
3534607	23092441	KK	2	participated in the design of this study|supervised this study and edited manuscript	supervised this study and edited manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
3534607	23092441	MU	2	participated in the design of this study|supervised this study and edited manuscript	participated in the design of this study	Conceived and designed the experiments	Methodology	YES
3534607	23092441	MU	2	participated in the design of this study|supervised this study and edited manuscript	supervised this study and edited manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
6468264	30993854	DH	2	contributed to the study design, data analysis and interpretation	contributed to the study design, data analysis and interpretation	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Methodology|Resources	YES
6468264	30993854	DN	2	contributed to the study design and interpretation	contributed to the study design and interpretation	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
6468264	30993854	ER	2	participated in data collection and interpretation	participated in data collection and interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6468264	30993854	GM	2	participated in data collection and interpretation	participated in data collection and interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6468264	30993854	JR	2	contributed to the study design, data analysis and interpretation|drafted the first version of the manuscript, which all authors subsequently reviewed, edited and approved	contributed to the study design, data analysis and interpretation	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Methodology|Resources	YES
6468264	30993854	JR	2	contributed to the study design, data analysis and interpretation|drafted the first version of the manuscript, which all authors subsequently reviewed, edited and approved	drafted the first version of the manuscript, which all authors subsequently reviewed, edited and approved	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6468264	30993854	JS	2	contributed to the study design and interpretation	contributed to the study design and interpretation	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
6468264	30993854	KA	2	contributed to the study design, data analysis and interpretation	contributed to the study design, data analysis and interpretation	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Methodology|Resources	YES
6468264	30993854	MB	2	contributed to data analysis and interpretation	contributed to data analysis and interpretation	Analyzed the data	Formal analysis	YES
6468264	30993854	MR	2	participated in data collection and interpretation	participated in data collection and interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6468264	30993854	MY	2	contributed to the study design, data analysis and interpretation	contributed to the study design, data analysis and interpretation	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Methodology|Resources	YES
6468264	30993854	QS	2	contributed to the study design, data analysis and interpretation	contributed to the study design, data analysis and interpretation	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Methodology|Resources	YES
6468264	30993854	VS	2	participated in data collection and interpretation	participated in data collection and interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4568330	26417598	Munsoo Kim	2	contributed equally to this research as first authors	contributed equally to this research as first authors	-	-	NO
4568330	26417598	Oh Jeong Kwon	2	contributed equally to this research as first authors	contributed equally to this research as first authors	-	-	NO
5508778	28701198	CSC	2	designed the algorithms and developed the software|performed experiments|wrote the manuscript	designed the algorithms and developed the software	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
5508778	28701198	CSC	2	designed the algorithms and developed the software|performed experiments|wrote the manuscript	performed experiments	Performed the experiments	Investigation	YES
5508778	28701198	CSC	2	designed the algorithms and developed the software|performed experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5508778	28701198	DB	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5508778	28701198	JG	2	designed the algorithms and developed the software|performed experiments|wrote the manuscript	designed the algorithms and developed the software	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
5508778	28701198	JG	2	designed the algorithms and developed the software|performed experiments|wrote the manuscript	performed experiments	Performed the experiments	Investigation	YES
5508778	28701198	JG	2	designed the algorithms and developed the software|performed experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5508778	28701198	MP	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5508778	28701198	SK	2	performed experiments|wrote the manuscript	performed experiments	Performed the experiments	Investigation	YES
5508778	28701198	SK	2	performed experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5670358	29163586	AS	2	developed the model and wrote the manuscript	developed the model and wrote the manuscript	Performed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5670358	29163586	TO	2	developed the model and wrote the manuscript|analyzed the model	developed the model and wrote the manuscript	Performed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5670358	29163586	TO	2	developed the model and wrote the manuscript|analyzed the model	analyzed the model	Performed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5954472	29760116	G.S.	2	helped the design of the study and analysis	helped the design of the study and analysis	Conceived and designed the experiments	Methodology	YES
5954472	29760116	H.D.	2	helped the design of the study and analysis	helped the design of the study and analysis	Conceived and designed the experiments	Methodology	YES
5954472	29760116	J.K.	2	helped the design of the study and analysis	helped the design of the study and analysis	Conceived and designed the experiments	Methodology	YES
5954472	29760116	M.B.	2	helped the design of the study and analysis	helped the design of the study and analysis	Conceived and designed the experiments	Methodology	YES
5954472	29760116	N.W.	2	performed data analysis and drafted the manuscript	performed data analysis and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5954472	29760116	O.S.	2	performed data analysis and drafted the manuscript	performed data analysis and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5954472	29760116	S.N.	2	helped the design of the study and analysis	helped the design of the study and analysis	Conceived and designed the experiments	Methodology	YES
4411112	25915940	ATHF	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411112	25915940	ATHF	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411112	25915940	BAG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411112	25915940	BAG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411112	25915940	BAG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411112	25915940	CAT	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper|Designed and performed sensitivity analyses	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411112	25915940	CAT	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper|Designed and performed sensitivity analyses	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411112	25915940	CAT	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper|Designed and performed sensitivity analyses	Designed and performed sensitivity analyses	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4411112	25915940	KE	PLoS5	Wrote the paper|Provided critical edits after first draft and subsequent drafts	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411112	25915940	KE	PLoS5	Wrote the paper|Provided critical edits after first draft and subsequent drafts	Provided critical edits after first draft and subsequent drafts	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4411112	25915940	KGH	PLoS5	Conceived and designed the experiments|Wrote the paper|Designed the figures|Designed and populated tables	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411112	25915940	KGH	PLoS5	Conceived and designed the experiments|Wrote the paper|Designed the figures|Designed and populated tables	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411112	25915940	KGH	PLoS5	Conceived and designed the experiments|Wrote the paper|Designed the figures|Designed and populated tables	Designed the figures	Conceived and designed the experiments	Visualization	YES
4411112	25915940	KGH	PLoS5	Conceived and designed the experiments|Wrote the paper|Designed the figures|Designed and populated tables	Designed and populated tables	Conceived and designed the experiments	-	YES
4411112	25915940	KIK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the figures|Designed and performed sensitivity analyses	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411112	25915940	KIK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the figures|Designed and performed sensitivity analyses	Analyzed the data	Analyzed the data	Formal analysis	YES
4411112	25915940	KIK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the figures|Designed and performed sensitivity analyses	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411112	25915940	KIK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the figures|Designed and performed sensitivity analyses	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411112	25915940	KIK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the figures|Designed and performed sensitivity analyses	Designed the figures	Conceived and designed the experiments	Visualization	YES
4411112	25915940	KIK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the figures|Designed and performed sensitivity analyses	Designed and performed sensitivity analyses	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4411112	25915940	LPP	PLoS5	Wrote the paper|Provided critical edits after first draft and subsequent drafts	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411112	25915940	LPP	PLoS5	Wrote the paper|Provided critical edits after first draft and subsequent drafts	Provided critical edits after first draft and subsequent drafts	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4411112	25915940	MRC	PLoS5	Wrote the paper|Provided critical edits after first draft and subsequent drafts	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411112	25915940	MRC	PLoS5	Wrote the paper|Provided critical edits after first draft and subsequent drafts	Provided critical edits after first draft and subsequent drafts	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4411112	25915940	POJ	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411112	25915940	POJ	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6474421	23993060	BL	2	added further thoughts and contributed to the writing	added further thoughts and contributed to the writing	Wrote the paper	-	YES
6474421	23993060	CO	2	conceptualized the manuscript and wrote the first draft	conceptualized the manuscript and wrote the first draft	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4411113	25915801	CAH	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411113	25915801	CAH	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411113	25915801	MDD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411113	25915801	MDD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411113	25915801	MDD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411113	25915801	MDD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411113	25915801	NES	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411113	25915801	NES	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411113	25915801	NES	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411113	25915801	TG	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411113	25915801	TG	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1828622	17389921	LP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1828622	17389921	LP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1828622	17389921	LP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1828622	17389921	LP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1828622	17389921	PA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1828622	17389921	PA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1828622	17389921	PA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1828622	17389921	PA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1828622	17389921	SA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1828622	17389921	SA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1828622	17389921	SA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1828622	17389921	SA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1828622	17389921	VL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1828622	17389921	VL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1828622	17389921	VL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5670359	29163593	FW	PLoS52	carried out the experiments|analyzed the data|wrote the manuscript	carried out the experiments	Performed the experiments	Investigation	YES
5670359	29163593	FW	PLoS52	carried out the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5670359	29163593	FW	PLoS52	carried out the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5670359	29163593	HQ	PLoS52	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5670359	29163593	JZ	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5670359	29163593	KY	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5670359	29163593	LBY	PLoS52	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5670359	29163593	LJY	PLoS52	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5670359	29163593	LX	PLoS52	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5670359	29163593	MC	PLoS52	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5670359	29163593	MX	PLoS52	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5670359	29163593	QC	PLoS52	designed the study|analyzed the data|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5670359	29163593	QC	PLoS52	designed the study|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5670359	29163593	QC	PLoS52	designed the study|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5670359	29163593	RQ	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5670359	29163593	SX	PLoS52	designed the study|analyzed the data|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5670359	29163593	SX	PLoS52	designed the study|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5670359	29163593	SX	PLoS52	designed the study|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5670359	29163593	WG	PLoS52	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5670359	29163593	WS	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5670359	29163593	ZC	PLoS52	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5508781	28701220	BS	2	performed data analysis, interpretation and revision	performed data analysis, interpretation and revision	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5508781	28701220	CQ	2	performed molecular genotypic data analysis	performed molecular genotypic data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5508781	28701220	ED	2	performed field test|performed molecular genotypic data analysis	performed field test	Performed the experiments	Investigation	YES
5508781	28701220	ED	2	performed field test|performed molecular genotypic data analysis	performed molecular genotypic data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5508781	28701220	GJ	2	performed data analysis, interpretation and revision	performed data analysis, interpretation and revision	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5508781	28701220	LY	2	performed data analysis, interpretation and revision|performed molecular genotypic data analysis|prepared the manuscript	performed data analysis, interpretation and revision	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5508781	28701220	LY	2	performed data analysis, interpretation and revision|performed molecular genotypic data analysis|prepared the manuscript	performed molecular genotypic data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5508781	28701220	LY	2	performed data analysis, interpretation and revision|performed molecular genotypic data analysis|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5508781	28701220	MEF	2	performed data analysis, interpretation and revision	performed data analysis, interpretation and revision	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5508781	28701220	NH	2	prepared the population	prepared the population	-	-	NO
5508781	28701220	PBC	2	provided project planning and coordination|prepared the manuscript	provided project planning and coordination	Conceived and designed the experiments	Methodology|Project administration	YES
5508781	28701220	PBC	2	provided project planning and coordination|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5508781	28701220	QS	2	provided project planning and coordination|performed data analysis, interpretation and revision|performed molecular genotypic data analysis|prepared the manuscript	provided project planning and coordination	Conceived and designed the experiments	Methodology|Project administration	YES
5508781	28701220	QS	2	provided project planning and coordination|performed data analysis, interpretation and revision|performed molecular genotypic data analysis|prepared the manuscript	performed data analysis, interpretation and revision	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5508781	28701220	QS	2	provided project planning and coordination|performed data analysis, interpretation and revision|performed molecular genotypic data analysis|prepared the manuscript	performed molecular genotypic data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5508781	28701220	QS	2	provided project planning and coordination|performed data analysis, interpretation and revision|performed molecular genotypic data analysis|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5508781	28701220	SL	2	performed data analysis, interpretation and revision	performed data analysis, interpretation and revision	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5508781	28701220	SR	2	performed data analysis, interpretation and revision	performed data analysis, interpretation and revision	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4411114	25915037	MSS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Developed the model|Designed and tested the simulation	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411114	25915037	MSS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Developed the model|Designed and tested the simulation	Performed the experiments	Performed the experiments	Investigation	YES
4411114	25915037	MSS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Developed the model|Designed and tested the simulation	Analyzed the data	Analyzed the data	Formal analysis	YES
4411114	25915037	MSS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Developed the model|Designed and tested the simulation	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411114	25915037	MSS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Developed the model|Designed and tested the simulation	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411114	25915037	MSS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Developed the model|Designed and tested the simulation	Developed the model	Performed the experiments	Methodology	YES
4411114	25915037	MSS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Developed the model|Designed and tested the simulation	Designed and tested the simulation	Conceived and designed the experiments|Performed the experiments	Formal analysis|Investigation	YES
1828623	17406665	MN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1828623	17406665	MN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1828623	17406665	MN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1828623	17406665	MN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1828623	17406665	MN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1828623	17406665	MW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1828623	17406665	MW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1828623	17406665	MW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1828623	17406665	MW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1828623	17406665	MW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5670501	29163595	JS	2	conceived and supervised study, helped to interpret data, and finalized manuscript	conceived and supervised study, helped to interpret data, and finalized manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Supervision|Writing - Review & Editing	YES
5670501	29163595	MO	2	conducted all live cell imaging|wrote first draft of the manuscript with input from all co-authors	conducted all live cell imaging	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
5670501	29163595	MO	2	conducted all live cell imaging|wrote first draft of the manuscript with input from all co-authors	wrote first draft of the manuscript with input from all co-authors	Wrote the paper	Writing - Original Draft	YES
5670501	29163595	PV	2	conducted all live cell imaging	conducted all live cell imaging	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
4568335	26417603	Both authors	2	contributed equally to the paper formulation	contributed equally to the paper formulation	Conceived and designed the experiments	Conceptualization	YES
5508783	28701230	ATV	PLoS52	conceived and designed the experiments, performed the experiments, analysed the data, and contributed substantially to writing the manuscript	conceived and designed the experiments, performed the experiments, analysed the data, and contributed substantially to writing the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5508783	28701230	JGER	PLoS52	conceived, designed, and performed experiments, and analysed the data	conceived, designed, and performed experiments, and analysed the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation|Methodology	YES
5508783	28701230	KHT	PLoS52	conceived, designed, and performed the experiments, analysed the data, prepared the tables and figures, and wrote the manuscript	conceived, designed, and performed the experiments, analysed the data, prepared the tables and figures, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Visualization|Writing - Original Draft	YES
5508783	28701230	MA	PLoS52	conceived and designed and performed experiments, and analysed the data	conceived and designed and performed experiments, and analysed the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation|Methodology	YES
5508783	28701230	MF	PLoS52	analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
5508783	28701230	SJC	PLoS52	conceived and designed the experiments, and analysed the data	conceived and designed the experiments, and analysed the data	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
5508783	28701230	all authors	PLoS52	read and commented on the manuscript at various production stages	read and commented on the manuscript at various production stages	-	-	NO
1828624	17389910	AA	1	Contributed to the planning of the experiments and data analysis|Contributed to writing and editing the text	Contributed to the planning of the experiments and data analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Methodology|Resources	YES
1828624	17389910	AA	1	Contributed to the planning of the experiments and data analysis|Contributed to writing and editing the text	Contributed to writing and editing the text	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
1828624	17389910	DH	1	Participated in the planning of the experiments and the data analysis and wrote most of the text	Participated in the planning of the experiments and the data analysis and wrote most of the text	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
1828624	17389910	VR	1	Had the main role in planning the experiments and performed all experiments and the data analysis|Contributed to writing and editing the text	Had the main role in planning the experiments and performed all experiments and the data analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
1828624	17389910	VR	1	Had the main role in planning the experiments and performed all experiments and the data analysis|Contributed to writing and editing the text	Contributed to writing and editing the text	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4411115	25915664	HZ	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411115	25915664	HZ	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411115	25915664	TS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411115	25915664	TS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411115	25915664	TS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411115	25915664	YKK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5670874	29163597	All authors	2	have read and approved the manuscript	have read and approved the manuscript	-	-	NO
5670874	29163597	BS	2	obtained the research funding|gave critical suggestions on manuscript preparation	obtained the research funding	-	Funding acquisition	YES
5670874	29163597	BS	2	obtained the research funding|gave critical suggestions on manuscript preparation	gave critical suggestions on manuscript preparation	Wrote the paper	Writing - Original Draft	YES
5670874	29163597	FL	2	gave critical suggestions on manuscript preparation	gave critical suggestions on manuscript preparation	Wrote the paper	Writing - Original Draft	YES
5670874	29163597	GF	2	obtained the research funding|gave critical suggestions on manuscript preparation	obtained the research funding	-	Funding acquisition	YES
5670874	29163597	GF	2	obtained the research funding|gave critical suggestions on manuscript preparation	gave critical suggestions on manuscript preparation	Wrote the paper	Writing - Original Draft	YES
5670874	29163597	HC	2	designed and supervised the study and wrote the manuscript|performed the microscopy	designed and supervised the study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Original Draft	YES
5670874	29163597	HC	2	designed and supervised the study and wrote the manuscript|performed the microscopy	performed the microscopy	Performed the experiments	Investigation	YES
5670874	29163597	LW	2	performed the microscopy|performed the malting and biochemical analyses|determined qpcr targets and designed primers	performed the microscopy	Performed the experiments	Investigation	YES
5670874	29163597	LW	2	performed the microscopy|performed the malting and biochemical analyses|determined qpcr targets and designed primers	performed the malting and biochemical analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5670874	29163597	LW	2	performed the microscopy|performed the malting and biochemical analyses|determined qpcr targets and designed primers	determined qpcr targets and designed primers	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5670874	29163597	NB	2	designed and supervised the study and wrote the manuscript|determined qpcr targets and designed primers	designed and supervised the study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Original Draft	YES
5670874	29163597	NB	2	designed and supervised the study and wrote the manuscript|determined qpcr targets and designed primers	determined qpcr targets and designed primers	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5670874	29163597	NS	2	performed the qpcr	performed the qpcr	Performed the experiments	Investigation	YES
5670874	29163597	RB	2	obtained the research funding|gave critical suggestions on manuscript preparation	obtained the research funding	-	Funding acquisition	YES
5670874	29163597	RB	2	obtained the research funding|gave critical suggestions on manuscript preparation	gave critical suggestions on manuscript preparation	Wrote the paper	Writing - Original Draft	YES
5670874	29163597	SK	2	performed the malting and biochemical analyses	performed the malting and biochemical analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5512735	28716118	All authors	2	reviewed the results and approved the final version of the manuscript	reviewed the results and approved the final version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5512735	28716118	GRL	2	conceived the study and wrote the paper	conceived the study and wrote the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5512735	28716118	JL	2	performed and analyzed all the date	performed and analyzed all the date	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5512735	28716118	JYZ	2	designed the study and revised the manuscript	designed the study and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5512735	28716118	MYZ	2	performed and analyzed all the date	performed and analyzed all the date	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5512735	28716118	SLJ	2	performed and analyzed all the date	performed and analyzed all the date	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5512735	28716118	SS	2	conceived the study and wrote the paper|designed the study and revised the manuscript	conceived the study and wrote the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5512735	28716118	SS	2	conceived the study and wrote the paper|designed the study and revised the manuscript	designed the study and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5512735	28716118	XFZ	2	performed and analyzed all the date	performed and analyzed all the date	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5512735	28716118	YXZ	2	performed and analyzed all the date	performed and analyzed all the date	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5990661	29807898	The authors	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
1828625	17406667	OC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1828625	17406667	OC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1828625	17406667	OC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1828625	17406667	OC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1828625	17406667	PC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Did the majority of the computer programming	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1828625	17406667	PC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Did the majority of the computer programming	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1828625	17406667	PC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Did the majority of the computer programming	Did the majority of the computer programming	Contributed reagents/materials/analysis tools	Formal analysis|Software	YES
4411116	25915775	FMJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411116	25915775	FMJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411116	25915775	FMJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411116	25915775	FMJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411116	25915775	JSV	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411116	25915775	JSV	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411116	25915775	JSV	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411116	25915775	JSV	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411116	25915775	KH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411116	25915775	KH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411116	25915775	KH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411116	25915775	KH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411116	25915775	KH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411116	25915775	MDS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411116	25915775	MDS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411116	25915775	MDS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411116	25915775	MDS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411116	25915775	MDS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5512810	28716048	BCT	2	all contributed to experimental design, data collection, data analysis and writing of the paper	all contributed to experimental design, data collection, data analysis and writing of the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
5512810	28716048	KK	2	all contributed to experimental design, data collection, data analysis and writing of the paper	all contributed to experimental design, data collection, data analysis and writing of the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
5512810	28716048	KXC	2	all contributed to experimental design, data collection, data analysis and writing of the paper	all contributed to experimental design, data collection, data analysis and writing of the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
5512810	28716048	LEG	2	all contributed to experimental design, data collection, data analysis and writing of the paper	all contributed to experimental design, data collection, data analysis and writing of the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
5512810	28716048	MMG	2	all contributed to experimental design, data collection, data analysis and writing of the paper	all contributed to experimental design, data collection, data analysis and writing of the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
5671031	29163578	All authors	2	revised the manuscript, read and approved the final manuscript	revised the manuscript, read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5671031	29163578	SKG	2	provided the breeding material, pedigree data and data of production environments	provided the breeding material, pedigree data and data of production environments	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5671031	29163578	SM	2	conceived and designed the experiment|conducted the experimental work|contributed to the data analysis and interpreted the results|wrote the paper under the	conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5671031	29163578	SM	2	conceived and designed the experiment|conducted the experimental work|contributed to the data analysis and interpreted the results|wrote the paper under the	conducted the experimental work	Performed the experiments	Investigation	YES
5671031	29163578	SM	2	conceived and designed the experiment|conducted the experimental work|contributed to the data analysis and interpreted the results|wrote the paper under the	contributed to the data analysis and interpreted the results	Analyzed the data	Formal analysis	YES
5671031	29163578	SM	2	conceived and designed the experiment|conducted the experimental work|contributed to the data analysis and interpreted the results|wrote the paper under the	wrote the paper under the	Wrote the paper	Writing - Original Draft	YES
5671031	29163578	VV	2	conceived and designed the experiment|contributed to the data analysis and interpreted the results|supervised the wrote the paper under the	conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5671031	29163578	VV	2	conceived and designed the experiment|contributed to the data analysis and interpreted the results|supervised the wrote the paper under the	contributed to the data analysis and interpreted the results	Analyzed the data	Formal analysis	YES
5671031	29163578	VV	2	conceived and designed the experiment|contributed to the data analysis and interpreted the results|supervised the wrote the paper under the	supervised the wrote the paper under the	Wrote the paper	Supervision|Writing - Original Draft	YES
1828626	17389923	DG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1828626	17389923	DG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1828626	17389923	DG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1828626	17389923	DG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411117	25915758	BJ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411117	25915758	GW	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411117	25915758	GW	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411117	25915758	JZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411117	25915758	LG	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4411117	25915758	LG	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4411117	25915758	MH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411117	25915758	YQ	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411117	25915758	YQ	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4411117	25915758	YQ	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1828628	17406668	AH	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1828628	17406668	AI	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1828628	17406668	CT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1828628	17406668	CT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1828628	17406668	CT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1828628	17406668	IP	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1828628	17406668	LR	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1828628	17406668	LR	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1828628	17406668	SO	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1828628	17406668	SO	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5512946	28716006	E.E.K.	PLoS52	performed the numerical work	performed the numerical work	Performed the experiments	Formal analysis|Investigation	YES
5512946	28716006	F.Z.	PLoS52	performed the experiments, helped draft the manuscript|conceived, designed and led the study, interpreted data and wrote the manuscript	performed the experiments, helped draft the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5512946	28716006	F.Z.	PLoS52	performed the experiments, helped draft the manuscript|conceived, designed and led the study, interpreted data and wrote the manuscript	conceived, designed and led the study, interpreted data and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
5512946	28716006	H.Q.	PLoS52	designed research|conceived, designed and led the study, interpreted data and wrote the manuscript|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
5512946	28716006	H.Q.	PLoS52	designed research|conceived, designed and led the study, interpreted data and wrote the manuscript|wrote the paper	conceived, designed and led the study, interpreted data and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
5512946	28716006	H.Q.	PLoS52	designed research|conceived, designed and led the study, interpreted data and wrote the manuscript|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5512946	28716006	J.K.	PLoS52	suggested strategies, interpreted data, advised on analyses, and helped draft	suggested strategies, interpreted data, advised on analyses, and helped draft	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5512946	28716006	K.K.C.	PLoS52	performed the numerical work	performed the numerical work	Performed the experiments	Formal analysis|Investigation	YES
5512946	28716006	L.W.	PLoS52	designed research|conceived, designed and led the study, interpreted data and wrote the manuscript|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
5512946	28716006	L.W.	PLoS52	designed research|conceived, designed and led the study, interpreted data and wrote the manuscript|wrote the paper	conceived, designed and led the study, interpreted data and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
5512946	28716006	L.W.	PLoS52	designed research|conceived, designed and led the study, interpreted data and wrote the manuscript|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5512946	28716006	S.R.	PLoS52	performed the numerical work	performed the numerical work	Performed the experiments	Formal analysis|Investigation	YES
5512946	28716006	V.R.I.	PLoS52	suggested strategies, interpreted data, advised on analyses, and helped draft	suggested strategies, interpreted data, advised on analyses, and helped draft	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4568348	26417601	Christos Papadimitriou	2	contributed equally	contributed equally	-	-	NO
4568348	26417601	Mehmet Ilyas Cosacak	2	contributed equally	contributed equally	-	-	NO
4411118	25915629	GZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411118	25915629	GZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411118	25915629	GZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411118	25915629	QZ	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4411118	25915629	QZ	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4411118	25915629	TC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411118	25915629	YH	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4411118	25915629	YH	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4411118	25915629	YL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411118	25915629	YL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4411118	25915629	YL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4411118	25915629	ZY	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4411118	25915629	ZY	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
6107538	30082309	P.W.	2	drafted the manuscript, and contributed to the intellectual vision of the manuscript	drafted the manuscript, and contributed to the intellectual vision of the manuscript	Wrote the paper	Writing - Original Draft	YES
6107538	30082309	S.O.	2	drafted the manuscript, and contributed to the intellectual vision of the manuscript	drafted the manuscript, and contributed to the intellectual vision of the manuscript	Wrote the paper	Writing - Original Draft	YES
5671467	29163562	All authors	2	contributed to revisions and commented on previous versions of the manuscript	contributed to revisions and commented on previous versions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5671467	29163562	CK	2	planned the experiments and supervised the study|contributed in the field experiments and collected the data|analyzed the data, discussed the main structure and wrote the manuscript	planned the experiments and supervised the study	Conceived and designed the experiments	Conceptualization|Supervision	YES
5671467	29163562	CK	2	planned the experiments and supervised the study|contributed in the field experiments and collected the data|analyzed the data, discussed the main structure and wrote the manuscript	contributed in the field experiments and collected the data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5671467	29163562	CK	2	planned the experiments and supervised the study|contributed in the field experiments and collected the data|analyzed the data, discussed the main structure and wrote the manuscript	analyzed the data, discussed the main structure and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5671467	29163562	DV	2	contributed in the field experiments and collected the data	contributed in the field experiments and collected the data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5671467	29163562	FD	2	contributed in the field experiments and collected the data	contributed in the field experiments and collected the data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5671467	29163562	FM	2	planned the experiments and supervised the study|contributed in the field experiments and collected the data	planned the experiments and supervised the study	Conceived and designed the experiments	Conceptualization|Supervision	YES
5671467	29163562	FM	2	planned the experiments and supervised the study|contributed in the field experiments and collected the data	contributed in the field experiments and collected the data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5671467	29163562	GJ	2	contributed in the field experiments and collected the data	contributed in the field experiments and collected the data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5671467	29163562	KS	2	planned the experiments and supervised the study|contributed in the field experiments and collected the data|analyzed the data, discussed the main structure and wrote the manuscript	planned the experiments and supervised the study	Conceived and designed the experiments	Conceptualization|Supervision	YES
5671467	29163562	KS	2	planned the experiments and supervised the study|contributed in the field experiments and collected the data|analyzed the data, discussed the main structure and wrote the manuscript	contributed in the field experiments and collected the data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5671467	29163562	KS	2	planned the experiments and supervised the study|contributed in the field experiments and collected the data|analyzed the data, discussed the main structure and wrote the manuscript	analyzed the data, discussed the main structure and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5671467	29163562	MF	2	contributed in the field experiments and collected the data|analyzed the data, discussed the main structure and wrote the manuscript	contributed in the field experiments and collected the data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5671467	29163562	MF	2	contributed in the field experiments and collected the data|analyzed the data, discussed the main structure and wrote the manuscript	analyzed the data, discussed the main structure and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5671467	29163562	MM	2	planned the experiments and supervised the study|contributed in the field experiments and collected the data	planned the experiments and supervised the study	Conceived and designed the experiments	Conceptualization|Supervision	YES
5671467	29163562	MM	2	planned the experiments and supervised the study|contributed in the field experiments and collected the data	contributed in the field experiments and collected the data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5671467	29163562	MvdH	2	planned the experiments and supervised the study|contributed in the field experiments and collected the data	planned the experiments and supervised the study	Conceived and designed the experiments	Conceptualization|Supervision	YES
5671467	29163562	MvdH	2	planned the experiments and supervised the study|contributed in the field experiments and collected the data	contributed in the field experiments and collected the data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5671467	29163562	NI	2	contributed in the field experiments and collected the data|analyzed the data, discussed the main structure and wrote the manuscript	contributed in the field experiments and collected the data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5671467	29163562	NI	2	contributed in the field experiments and collected the data|analyzed the data, discussed the main structure and wrote the manuscript	analyzed the data, discussed the main structure and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5671467	29163562	RBP	2	contributed in the field experiments and collected the data	contributed in the field experiments and collected the data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5671467	29163562	RCH	2	planned the experiments and supervised the study|contributed in the field experiments and collected the data|analyzed the data, discussed the main structure and wrote the manuscript	planned the experiments and supervised the study	Conceived and designed the experiments	Conceptualization|Supervision	YES
5671467	29163562	RCH	2	planned the experiments and supervised the study|contributed in the field experiments and collected the data|analyzed the data, discussed the main structure and wrote the manuscript	contributed in the field experiments and collected the data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5671467	29163562	RCH	2	planned the experiments and supervised the study|contributed in the field experiments and collected the data|analyzed the data, discussed the main structure and wrote the manuscript	analyzed the data, discussed the main structure and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5671467	29163562	SB	2	contributed in the field experiments and collected the data	contributed in the field experiments and collected the data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5671467	29163562	TT	2	planned the experiments and supervised the study	planned the experiments and supervised the study	Conceived and designed the experiments	Conceptualization|Supervision	YES
5671467	29163562	XC	2	contributed in the field experiments and collected the data|analyzed the data, discussed the main structure and wrote the manuscript	contributed in the field experiments and collected the data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5671467	29163562	XC	2	contributed in the field experiments and collected the data|analyzed the data, discussed the main structure and wrote the manuscript	analyzed the data, discussed the main structure and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6107542	30082302	All authors	2	contributed to the conceptualization and design of the study, and writing and review of the manuscript	contributed to the conceptualization and design of the study, and writing and review of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
6107542	30082302	M.J.S.	2	executed the study	executed the study	Performed the experiments	Investigation	YES
1828629	17396163	AIB	1	Conceived and designed experiments	Conceived and designed experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1828629	17396163	GL	1	Assisted with mouse experiments	Assisted with mouse experiments	Performed the experiments	Investigation	YES
1828629	17396163	JAK	1	Performed all other experiments	Performed all other experiments	Performed the experiments	Investigation	YES
1828629	17396163	JHF	1	Conceived and designed experiments|Performed all other experiments	Conceived and designed experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1828629	17396163	JHF	1	Conceived and designed experiments|Performed all other experiments	Performed all other experiments	Performed the experiments	Investigation	YES
1828629	17396163	KD	1	Assisted with mouse experiments	Assisted with mouse experiments	Performed the experiments	Investigation	YES
1828629	17396163	RC	1	Assisted with mouse experiments	Assisted with mouse experiments	Performed the experiments	Investigation	YES
1828629	17396163	SH	1	Advised experiments and provided most of funding	Advised experiments and provided most of funding	-	Funding acquisition	YES
1828629	17396163	VC	1	Assisted with mouse experiments	Assisted with mouse experiments	Performed the experiments	Investigation	YES
4411119	25915641	AMW	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411119	25915641	AMW	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411119	25915641	AMW	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411119	25915641	AMW	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411119	25915641	HZX	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411119	25915641	JSW	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4411119	25915641	WQW	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4411119	25915641	XDY	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4411119	25915641	XDY	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411119	25915641	XYW	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411119	25915641	YLC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411119	25915641	YLC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411119	25915641	YLC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411119	25915641	ZKL	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411119	25915641	ZKL	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411119	25915641	ZXS	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411119	25915641	ZXS	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411119	25915641	ZXS	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411119	25915641	ZXS	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5671478	29163601	BL	PLoS52	revised the paper	revised the paper	Wrote the paper	Writing - Review & Editing	YES
5671478	29163601	FY	PLoS52	carried out plant inoculation and real time qpcr experiments	carried out plant inoculation and real time qpcr experiments	Performed the experiments	Investigation	YES
5671478	29163601	JF	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5671478	29163601	JW	PLoS52	carried out plant inoculation and real time qpcr experiments	carried out plant inoculation and real time qpcr experiments	Performed the experiments	Investigation	YES
5671478	29163601	JZ	PLoS52	conceived and designed the experiments|analyzed the data|wrote the paper|revised the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5671478	29163601	JZ	PLoS52	conceived and designed the experiments|analyzed the data|wrote the paper|revised the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5671478	29163601	JZ	PLoS52	conceived and designed the experiments|analyzed the data|wrote the paper|revised the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5671478	29163601	JZ	PLoS52	conceived and designed the experiments|analyzed the data|wrote the paper|revised the paper	revised the paper	Wrote the paper	Writing - Review & Editing	YES
5671478	29163601	XW	PLoS52	revised the paper	revised the paper	Wrote the paper	Writing - Review & Editing	YES
5671478	29163601	YW	PLoS52	carried out plant inoculation and real time qpcr experiments	carried out plant inoculation and real time qpcr experiments	Performed the experiments	Investigation	YES
5671478	29163601	all authors	PLoS52	reviewed the paper	reviewed the paper	Wrote the paper	Writing - Review & Editing	YES
5512948	28716036	JAC	2	designed and coordinated experiments|prepared the manuscript	designed and coordinated experiments	Conceived and designed the experiments	Methodology|Project administration	YES
5512948	28716036	JAC	2	designed and coordinated experiments|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5512948	28716036	LC	2	performed tf analyses	performed tf analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5512948	28716036	LLC	2	performed enhancer prediction and sequence analyses|prepared the manuscript	performed enhancer prediction and sequence analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5512948	28716036	LLC	2	performed enhancer prediction and sequence analyses|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
1828630	17406669	AT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1828630	17406669	AT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1828630	17406669	AT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1828630	17406669	AT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1828630	17406669	DD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1828630	17406669	DD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1828630	17406669	DD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1828630	17406669	JP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1828630	17406669	JP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1828630	17406669	JP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1828630	17406669	JP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411120	25915777	CW	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411120	25915777	CW	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411120	25915777	HS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411120	25915777	HS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4411120	25915777	HS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4411120	25915777	KZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411120	25915777	KZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411120	25915777	KZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411120	25915777	KZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411120	25915777	SZ	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411120	25915777	SZ	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411120	25915777	WZ	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411120	25915777	WZ	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
6107609	30126916	All authors	2	gave final approval for publication	gave final approval for publication	-	-	NO
6107609	30126916	All the authors	2	had an equal contribution	had an equal contribution	-	-	NO
1828636	17245444	DP	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1828636	17245444	DP	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1828636	17245444	KA	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1828636	17245444	KA	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1828636	17245444	KM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1828636	17245444	KM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1828636	17245444	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Arranged funding	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1828636	17245444	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Arranged funding	Performed the experiments	Performed the experiments	Investigation	YES
1828636	17245444	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Arranged funding	Analyzed the data	Analyzed the data	Formal analysis	YES
1828636	17245444	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Arranged funding	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1828636	17245444	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Arranged funding	Arranged funding	-	Funding acquisition	YES
1828636	17245444	NH	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1828636	17245444	NH	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1828636	17245444	PS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1997116	17908342	All authors	2	contributed equally to this work	contributed equally to this work	-	-	NO
4411121	25915040	CZ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4411121	25915040	CZ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4411121	25915040	CZ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411121	25915040	FM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4411121	25915040	FM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4411121	25915040	FM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411121	25915040	HC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411121	25915040	HC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411121	25915040	HC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411121	25915040	HC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411121	25915040	HC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411121	25915040	JD	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411121	25915040	MZ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4411121	25915040	MZ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4411121	25915040	MZ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411121	25915040	XG	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4411121	25915040	XG	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4411121	25915040	XG	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411121	25915040	XZ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411121	25915040	XZ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411121	25915040	YH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4411121	25915040	YH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4411121	25915040	YH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411121	25915040	YN	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411121	25915040	YZ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411121	25915040	YZ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411121	25915040	YZ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411121	25915040	YZ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5513125	28709399	ADMD	PLoS52	conceived and designed the experiments|contributed reagents, materials, and analysis tools|wrote the manuscript|prepared the figures|reviewed drafts of the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5513125	28709399	ADMD	PLoS52	conceived and designed the experiments|contributed reagents, materials, and analysis tools|wrote the manuscript|prepared the figures|reviewed drafts of the paper	contributed reagents, materials, and analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5513125	28709399	ADMD	PLoS52	conceived and designed the experiments|contributed reagents, materials, and analysis tools|wrote the manuscript|prepared the figures|reviewed drafts of the paper	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5513125	28709399	ADMD	PLoS52	conceived and designed the experiments|contributed reagents, materials, and analysis tools|wrote the manuscript|prepared the figures|reviewed drafts of the paper	prepared the figures	-	Visualization	YES
5513125	28709399	ADMD	PLoS52	conceived and designed the experiments|contributed reagents, materials, and analysis tools|wrote the manuscript|prepared the figures|reviewed drafts of the paper	reviewed drafts of the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5513125	28709399	CPH	PLoS52	performed the experiments|reviewed drafts of the paper	performed the experiments	Performed the experiments	Investigation	YES
5513125	28709399	CPH	PLoS52	performed the experiments|reviewed drafts of the paper	reviewed drafts of the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5513125	28709399	HW	PLoS52	contributed reagents, materials, and analysis tools	contributed reagents, materials, and analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5513125	28709399	JSV	PLoS52	analyzed the data|reviewed drafts of the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5513125	28709399	JSV	PLoS52	analyzed the data|reviewed drafts of the paper	reviewed drafts of the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5513125	28709399	MA	PLoS52	analyzed the data|reviewed drafts of the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5513125	28709399	MA	PLoS52	analyzed the data|reviewed drafts of the paper	reviewed drafts of the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5513125	28709399	MT	PLoS52	analyzed the data|wrote the manuscript|prepared the figures|reviewed drafts of the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5513125	28709399	MT	PLoS52	analyzed the data|wrote the manuscript|prepared the figures|reviewed drafts of the paper	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5513125	28709399	MT	PLoS52	analyzed the data|wrote the manuscript|prepared the figures|reviewed drafts of the paper	prepared the figures	-	Visualization	YES
5513125	28709399	MT	PLoS52	analyzed the data|wrote the manuscript|prepared the figures|reviewed drafts of the paper	reviewed drafts of the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5513125	28709399	MTA	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5513125	28709399	RAP	PLoS52	analyzed the data|reviewed drafts of the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5513125	28709399	RAP	PLoS52	analyzed the data|reviewed drafts of the paper	reviewed drafts of the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5513125	28709399	RB	PLoS52	analyzed the data|reviewed drafts of the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5513125	28709399	RB	PLoS52	analyzed the data|reviewed drafts of the paper	reviewed drafts of the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5513125	28709399	RW	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5513125	28709399	SJJ	PLoS52	analyzed the data|prepared the figures|reviewed drafts of the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5513125	28709399	SJJ	PLoS52	analyzed the data|prepared the figures|reviewed drafts of the paper	prepared the figures	-	Visualization	YES
5513125	28709399	SJJ	PLoS52	analyzed the data|prepared the figures|reviewed drafts of the paper	reviewed drafts of the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5513125	28709399	TDR	PLoS52	conceived and designed the experiments|analyzed the data|wrote the manuscript|prepared the figures|reviewed drafts of the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5513125	28709399	TDR	PLoS52	conceived and designed the experiments|analyzed the data|wrote the manuscript|prepared the figures|reviewed drafts of the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5513125	28709399	TDR	PLoS52	conceived and designed the experiments|analyzed the data|wrote the manuscript|prepared the figures|reviewed drafts of the paper	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5513125	28709399	TDR	PLoS52	conceived and designed the experiments|analyzed the data|wrote the manuscript|prepared the figures|reviewed drafts of the paper	prepared the figures	-	Visualization	YES
5513125	28709399	TDR	PLoS52	conceived and designed the experiments|analyzed the data|wrote the manuscript|prepared the figures|reviewed drafts of the paper	reviewed drafts of the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5671499	29163604	AK	2	conceived the study and was involved in critical revision of the manuscript and final approval of the version to be published	conceived the study and was involved in critical revision of the manuscript and final approval of the version to be published	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5671499	29163604	KR	2	was involved in data analysis	was involved in data analysis	Analyzed the data	Formal analysis	YES
5671499	29163604	NS	2	was involved in conducting the experiment, analysis, data interpretation, and drafting of the manuscript	was involved in conducting the experiment, analysis, data interpretation, and drafting of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6107610	30126917	D.M.C.	2	participated in the a2 field trip|have synthesized findings related to the phase ii and a2 field trips that are already published, with hitherto unpublished results being provided for the a3 field trip	participated in the a2 field trip	-	-	NO
6107610	30126917	D.M.C.	2	participated in the a2 field trip|have synthesized findings related to the phase ii and a2 field trips that are already published, with hitherto unpublished results being provided for the a3 field trip	have synthesized findings related to the phase ii and a2 field trips that are already published, with hitherto unpublished results being provided for the a3 field trip	Performed the experiments	Investigation	YES
6107610	30126917	J.P.D.	2	have synthesized findings related to the phase ii and a2 field trips that are already published, with hitherto unpublished results being provided for the a3 field trip	have synthesized findings related to the phase ii and a2 field trips that are already published, with hitherto unpublished results being provided for the a3 field trip	Performed the experiments	Investigation	YES
6107610	30126917	S.W.	2	participated in the a3 field trip	participated in the a3 field trip	-	-	NO
1829175	17406670	LM	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1829175	17406670	LM	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1829175	17406670	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1829175	17406670	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1829175	17406670	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1829175	17406670	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1829175	17406670	NB	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1829175	17406670	NB	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1829175	17406670	SL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1829175	17406670	SL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1829175	17406670	SL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1829175	17406670	SL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2034594	17908290	JEH	2	participated in its design, coordinated and collected data and helped to draft the manuscript	participated in its design, coordinated and collected data and helped to draft the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Project administration|Writing - Original Draft	YES
2034594	17908290	RWM	2	participated in the design of the study, assisted in data collection, performed the statistical analysis, interpretation of data, and drafted the manuscript	participated in the design of the study, assisted in data collection, performed the statistical analysis, interpretation of data, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4883022	27234509	AF	PLoS52	conceived and designed the research|interpreted the results of the experiments|edited and revised the manuscript	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
4883022	27234509	AF	PLoS52	conceived and designed the research|interpreted the results of the experiments|edited and revised the manuscript	interpreted the results of the experiments	Analyzed the data	Formal analysis	YES
4883022	27234509	AF	PLoS52	conceived and designed the research|interpreted the results of the experiments|edited and revised the manuscript	edited and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4883022	27234509	FH	PLoS52	conceived and designed the research|performed the experiments|analysed the data|interpreted the results of the experiments|edited and revised the manuscript|approved the final version of the manuscript	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
4883022	27234509	FH	PLoS52	conceived and designed the research|performed the experiments|analysed the data|interpreted the results of the experiments|edited and revised the manuscript|approved the final version of the manuscript	performed the experiments	Performed the experiments	Investigation	YES
4883022	27234509	FH	PLoS52	conceived and designed the research|performed the experiments|analysed the data|interpreted the results of the experiments|edited and revised the manuscript|approved the final version of the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
4883022	27234509	FH	PLoS52	conceived and designed the research|performed the experiments|analysed the data|interpreted the results of the experiments|edited and revised the manuscript|approved the final version of the manuscript	interpreted the results of the experiments	Analyzed the data	Formal analysis	YES
4883022	27234509	FH	PLoS52	conceived and designed the research|performed the experiments|analysed the data|interpreted the results of the experiments|edited and revised the manuscript|approved the final version of the manuscript	edited and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4883022	27234509	FH	PLoS52	conceived and designed the research|performed the experiments|analysed the data|interpreted the results of the experiments|edited and revised the manuscript|approved the final version of the manuscript	approved the final version of the manuscript	-	-	NO
4883022	27234509	JD	PLoS52	conceived and designed the research|performed the experiments|analysed the data|interpreted the results of the experiments|prepared the figures|drafted the manuscript|edited and revised the manuscript|approved the final version of the manuscript	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
4883022	27234509	JD	PLoS52	conceived and designed the research|performed the experiments|analysed the data|interpreted the results of the experiments|prepared the figures|drafted the manuscript|edited and revised the manuscript|approved the final version of the manuscript	performed the experiments	Performed the experiments	Investigation	YES
4883022	27234509	JD	PLoS52	conceived and designed the research|performed the experiments|analysed the data|interpreted the results of the experiments|prepared the figures|drafted the manuscript|edited and revised the manuscript|approved the final version of the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
4883022	27234509	JD	PLoS52	conceived and designed the research|performed the experiments|analysed the data|interpreted the results of the experiments|prepared the figures|drafted the manuscript|edited and revised the manuscript|approved the final version of the manuscript	interpreted the results of the experiments	Analyzed the data	Formal analysis	YES
4883022	27234509	JD	PLoS52	conceived and designed the research|performed the experiments|analysed the data|interpreted the results of the experiments|prepared the figures|drafted the manuscript|edited and revised the manuscript|approved the final version of the manuscript	prepared the figures	-	Visualization	YES
4883022	27234509	JD	PLoS52	conceived and designed the research|performed the experiments|analysed the data|interpreted the results of the experiments|prepared the figures|drafted the manuscript|edited and revised the manuscript|approved the final version of the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4883022	27234509	JD	PLoS52	conceived and designed the research|performed the experiments|analysed the data|interpreted the results of the experiments|prepared the figures|drafted the manuscript|edited and revised the manuscript|approved the final version of the manuscript	edited and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4883022	27234509	JD	PLoS52	conceived and designed the research|performed the experiments|analysed the data|interpreted the results of the experiments|prepared the figures|drafted the manuscript|edited and revised the manuscript|approved the final version of the manuscript	approved the final version of the manuscript	-	-	NO
4883022	27234509	ML	PLoS52	conceived and designed the research|interpreted the results of the experiments|edited and revised the manuscript	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
4883022	27234509	ML	PLoS52	conceived and designed the research|interpreted the results of the experiments|edited and revised the manuscript	interpreted the results of the experiments	Analyzed the data	Formal analysis	YES
4883022	27234509	ML	PLoS52	conceived and designed the research|interpreted the results of the experiments|edited and revised the manuscript	edited and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4883022	27234509	QTN	PLoS52	conceived and designed the research|performed the experiments|interpreted the results of the experiments|edited and revised the manuscript	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
4883022	27234509	QTN	PLoS52	conceived and designed the research|performed the experiments|interpreted the results of the experiments|edited and revised the manuscript	performed the experiments	Performed the experiments	Investigation	YES
4883022	27234509	QTN	PLoS52	conceived and designed the research|performed the experiments|interpreted the results of the experiments|edited and revised the manuscript	interpreted the results of the experiments	Analyzed the data	Formal analysis	YES
4883022	27234509	QTN	PLoS52	conceived and designed the research|performed the experiments|interpreted the results of the experiments|edited and revised the manuscript	edited and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4883022	27234509	SM	PLoS52	performed the experiments|analysed the data|prepared the figures	performed the experiments	Performed the experiments	Investigation	YES
4883022	27234509	SM	PLoS52	performed the experiments|analysed the data|prepared the figures	analysed the data	Analyzed the data	Formal analysis	YES
4883022	27234509	SM	PLoS52	performed the experiments|analysed the data|prepared the figures	prepared the figures	-	Visualization	YES
4883022	27234509	VF	PLoS52	analysed the data|interpreted the results of the experiments|prepared the figures|edited and revised the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
4883022	27234509	VF	PLoS52	analysed the data|interpreted the results of the experiments|prepared the figures|edited and revised the manuscript	interpreted the results of the experiments	Analyzed the data	Formal analysis	YES
4883022	27234509	VF	PLoS52	analysed the data|interpreted the results of the experiments|prepared the figures|edited and revised the manuscript	prepared the figures	-	Visualization	YES
4883022	27234509	VF	PLoS52	analysed the data|interpreted the results of the experiments|prepared the figures|edited and revised the manuscript	edited and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4883022	27234509	XL	PLoS52	conceived and designed the research|performed the experiments|analysed the data|interpreted the results of the experiments|prepared the figures|drafted the manuscript	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
4883022	27234509	XL	PLoS52	conceived and designed the research|performed the experiments|analysed the data|interpreted the results of the experiments|prepared the figures|drafted the manuscript	performed the experiments	Performed the experiments	Investigation	YES
4883022	27234509	XL	PLoS52	conceived and designed the research|performed the experiments|analysed the data|interpreted the results of the experiments|prepared the figures|drafted the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
4883022	27234509	XL	PLoS52	conceived and designed the research|performed the experiments|analysed the data|interpreted the results of the experiments|prepared the figures|drafted the manuscript	interpreted the results of the experiments	Analyzed the data	Formal analysis	YES
4883022	27234509	XL	PLoS52	conceived and designed the research|performed the experiments|analysed the data|interpreted the results of the experiments|prepared the figures|drafted the manuscript	prepared the figures	-	Visualization	YES
4883022	27234509	XL	PLoS52	conceived and designed the research|performed the experiments|analysed the data|interpreted the results of the experiments|prepared the figures|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5513335	28715998	CL	2	performed the library preparation and the sequencing	performed the library preparation and the sequencing	Performed the experiments	Investigation	YES
5513335	28715998	ED	2	designed the experiments, conducted the analyses and wrote the manuscript	designed the experiments, conducted the analyses and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5513335	28715998	M-CC	2	provided support for the bioinformatic analyses	provided support for the bioinformatic analyses	Analyzed the data	Formal analysis	YES
5513335	28715998	MM	2	provided support for the characterization of plant material	provided support for the characterization of plant material	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5513335	28715998	OP	2	supervised the work	supervised the work	-	Supervision	YES
4411122	25915208	AWC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411122	25915208	AWC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411122	25915208	AWC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411122	25915208	BV	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411122	25915208	BV	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411122	25915208	DS	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411122	25915208	DS	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4411122	25915208	DS	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411122	25915208	GA	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411122	25915208	GA	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411122	25915208	HG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411122	25915208	IP	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4411122	25915208	IP	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4411122	25915208	RLG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411122	25915208	RLG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411122	25915208	RLG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411122	25915208	RLG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411122	25915208	RLG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411122	25915208	WA	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411122	25915208	WA	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5671511	29163577	AS	2	calculated codon frequencies	calculated codon frequencies	Analyzed the data	Formal analysis	YES
5671511	29163577	CG	2	prepared the constructs, transfected protoplasts, and analyzed data	prepared the constructs, transfected protoplasts, and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5671511	29163577	CN	2	prepared the constructs, transfected protoplasts, and analyzed data	prepared the constructs, transfected protoplasts, and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5671511	29163577	KU	2	calculated codon frequencies	calculated codon frequencies	Analyzed the data	Formal analysis	YES
5671511	29163577	LS	2	prepared the constructs, transfected protoplasts, and analyzed data	prepared the constructs, transfected protoplasts, and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5671511	29163577	MB	2	prepared the constructs, transfected protoplasts, and analyzed data	prepared the constructs, transfected protoplasts, and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5671511	29163577	MH	2	prepared the constructs, transfected protoplasts, and analyzed data|designed the experiments|wrote the manuscript with contributions by all authors	prepared the constructs, transfected protoplasts, and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5671511	29163577	MH	2	prepared the constructs, transfected protoplasts, and analyzed data|designed the experiments|wrote the manuscript with contributions by all authors	designed the experiments	Conceived and designed the experiments	Methodology	YES
5671511	29163577	MH	2	prepared the constructs, transfected protoplasts, and analyzed data|designed the experiments|wrote the manuscript with contributions by all authors	wrote the manuscript with contributions by all authors	Wrote the paper	Writing - Original Draft	YES
5671511	29163577	MS-R	2	supervised the project|designed the experiments	supervised the project	-	Supervision	YES
5671511	29163577	MS-R	2	supervised the project|designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5671511	29163577	P-FP	2	supervised the project|designed the experiments	supervised the project	-	Supervision	YES
5671511	29163577	P-FP	2	supervised the project|designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5671511	29163577	SR	2	conceived of the work|supervised the project|designed the experiments|wrote the manuscript with contributions by all authors	conceived of the work	Conceived and designed the experiments	Conceptualization	YES
5671511	29163577	SR	2	conceived of the work|supervised the project|designed the experiments|wrote the manuscript with contributions by all authors	supervised the project	-	Supervision	YES
5671511	29163577	SR	2	conceived of the work|supervised the project|designed the experiments|wrote the manuscript with contributions by all authors	designed the experiments	Conceived and designed the experiments	Methodology	YES
5671511	29163577	SR	2	conceived of the work|supervised the project|designed the experiments|wrote the manuscript with contributions by all authors	wrote the manuscript with contributions by all authors	Wrote the paper	Writing - Original Draft	YES
2042499	17908285	BRS	2	conceived of the study, participated in design of the study, analyzed statistics, and helped to draft the manuscript	conceived of the study, participated in design of the study, analyzed statistics, and helped to draft the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
2042499	17908285	JFY	2	participated in design of the study, collected data, analyzed statistics, and drafted the manuscript	participated in design of the study, collected data, analyzed statistics, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
2042499	17908285	JJP	2	collected data and helped to draft the manuscript	collected data and helped to draft the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
2042499	17908285	LJW	2	participated in design of the study and helped to draft the manuscript	participated in design of the study and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
2042499	17908285	PAB	2	participated in design of the study and helped to draft the manuscript	participated in design of the study and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5671580	29163596	All authors	2	listed have made a substantial, direct and intellectual contribution to the work, and approved it for publication	listed have made a substantial, direct and intellectual contribution to the work, and approved it for publication	-	-	NO
4411123	25915405	BKT	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4411123	25915405	BKT	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411123	25915405	CA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411123	25915405	CA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411123	25915405	CA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411123	25915405	CA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411123	25915405	KN	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411123	25915405	KN	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411123	25915405	KN	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411123	25915405	SM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411123	25915405	YS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411123	25915405	YS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4411123	25915405	YS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1829176	17389924	SW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1829176	17389924	SW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1829176	17389924	SW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1829176	17389924	SW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1829176	17389924	SW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4883985	26116121	BA	2	supported cell culture of ovcar3 and skov3 cells	supported cell culture of ovcar3 and skov3 cells	Performed the experiments	Investigation	YES
4883985	26116121	DG	2	supported ex vivo analyses and immunofluorescence and immunohistochemistry experiments from tumor sections	supported ex vivo analyses and immunofluorescence and immunohistochemistry experiments from tumor sections	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4883985	26116121	FW	2	was responsible for the design of the study and critically revised the manuscript	was responsible for the design of the study and critically revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
4883985	26116121	MeW	2	was responsible for animal experiments, including analysis of the pet data	was responsible for animal experiments, including analysis of the pet data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4883985	26116121	MoW	2	was supporting all radiopharmacological experiments	was supporting all radiopharmacological experiments	-	-	NO
4883985	26116121	SEL	2	supported radiolabeling experiments	supported radiolabeling experiments	Performed the experiments	Investigation	YES
4883985	26116121	SS	2	was responsible for the synthesis and pharmacological evaluation of the immunoconjugates|was responsible for writing the manuscript	was responsible for the synthesis and pharmacological evaluation of the immunoconjugates	-	-	NO
4883985	26116121	SS	2	was responsible for the synthesis and pharmacological evaluation of the immunoconjugates|was responsible for writing the manuscript	was responsible for writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5513378	28705237	CF	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5513378	28705237	CK	PLoS52	wrote and/or edited the manuscript	wrote and/or edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5513378	28705237	ES	PLoS52	provided technical support and were responsible for sequencing	provided technical support and were responsible for sequencing	Performed the experiments	Investigation	YES
5513378	28705237	IK	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5513378	28705237	JB	PLoS52	provided technical support and were responsible for sequencing|wrote and/or edited the manuscript	provided technical support and were responsible for sequencing	Performed the experiments	Investigation	YES
5513378	28705237	JB	PLoS52	provided technical support and were responsible for sequencing|wrote and/or edited the manuscript	wrote and/or edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5513378	28705237	SW	PLoS52	conceived, designed and analysed the experiments|performed the experiments|wrote and/or edited the manuscript	conceived, designed and analysed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5513378	28705237	SW	PLoS52	conceived, designed and analysed the experiments|performed the experiments|wrote and/or edited the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5513378	28705237	SW	PLoS52	conceived, designed and analysed the experiments|performed the experiments|wrote and/or edited the manuscript	wrote and/or edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5671591	29163602	PZ	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper|reviewed and revised the paper|corrected the english language for the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5671591	29163602	PZ	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper|reviewed and revised the paper|corrected the english language for the paper	performed the experiments	Performed the experiments	Investigation	YES
5671591	29163602	PZ	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper|reviewed and revised the paper|corrected the english language for the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5671591	29163602	PZ	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper|reviewed and revised the paper|corrected the english language for the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5671591	29163602	PZ	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper|reviewed and revised the paper|corrected the english language for the paper	reviewed and revised the paper	Wrote the paper	Writing - Review & Editing	YES
5671591	29163602	PZ	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper|reviewed and revised the paper|corrected the english language for the paper	corrected the english language for the paper	Wrote the paper	Writing - Review & Editing	YES
5671591	29163602	SA	PLoS52	reviewed and revised the paper	reviewed and revised the paper	Wrote the paper	Writing - Review & Editing	YES
5671591	29163602	TC	PLoS52	performed the experiments|analyzed the data|reviewed and revised the paper	performed the experiments	Performed the experiments	Investigation	YES
5671591	29163602	TC	PLoS52	performed the experiments|analyzed the data|reviewed and revised the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5671591	29163602	TC	PLoS52	performed the experiments|analyzed the data|reviewed and revised the paper	reviewed and revised the paper	Wrote the paper	Writing - Review & Editing	YES
5671591	29163602	TW	PLoS52	performed the experiments|analyzed the data|reviewed and revised the paper|corrected the english language for the paper	performed the experiments	Performed the experiments	Investigation	YES
5671591	29163602	TW	PLoS52	performed the experiments|analyzed the data|reviewed and revised the paper|corrected the english language for the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5671591	29163602	TW	PLoS52	performed the experiments|analyzed the data|reviewed and revised the paper|corrected the english language for the paper	reviewed and revised the paper	Wrote the paper	Writing - Review & Editing	YES
5671591	29163602	TW	PLoS52	performed the experiments|analyzed the data|reviewed and revised the paper|corrected the english language for the paper	corrected the english language for the paper	Wrote the paper	Writing - Review & Editing	YES
5671591	29163602	XC	PLoS52	performed the experiments|wrote the paper|reviewed and revised the paper	performed the experiments	Performed the experiments	Investigation	YES
5671591	29163602	XC	PLoS52	performed the experiments|wrote the paper|reviewed and revised the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5671591	29163602	XC	PLoS52	performed the experiments|wrote the paper|reviewed and revised the paper	reviewed and revised the paper	Wrote the paper	Writing - Review & Editing	YES
5671591	29163602	XR	PLoS52	conceived and designed the experiments|performed the experiments|wrote the paper|reviewed and revised the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5671591	29163602	XR	PLoS52	conceived and designed the experiments|performed the experiments|wrote the paper|reviewed and revised the paper	performed the experiments	Performed the experiments	Investigation	YES
5671591	29163602	XR	PLoS52	conceived and designed the experiments|performed the experiments|wrote the paper|reviewed and revised the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5671591	29163602	XR	PLoS52	conceived and designed the experiments|performed the experiments|wrote the paper|reviewed and revised the paper	reviewed and revised the paper	Wrote the paper	Writing - Review & Editing	YES
5671591	29163602	YW	PLoS52	performed the experiments|reviewed and revised the paper	performed the experiments	Performed the experiments	Investigation	YES
5671591	29163602	YW	PLoS52	performed the experiments|reviewed and revised the paper	reviewed and revised the paper	Wrote the paper	Writing - Review & Editing	YES
5671591	29163602	ZJ	PLoS52	conceived and designed the experiments|analyzed the data|reviewed and revised the paper|corrected the english language for the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5671591	29163602	ZJ	PLoS52	conceived and designed the experiments|analyzed the data|reviewed and revised the paper|corrected the english language for the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5671591	29163602	ZJ	PLoS52	conceived and designed the experiments|analyzed the data|reviewed and revised the paper|corrected the english language for the paper	reviewed and revised the paper	Wrote the paper	Writing - Review & Editing	YES
5671591	29163602	ZJ	PLoS52	conceived and designed the experiments|analyzed the data|reviewed and revised the paper|corrected the english language for the paper	corrected the english language for the paper	Wrote the paper	Writing - Review & Editing	YES
4569756	26421281	Liang Wang	2	contributed equally to this work	contributed equally to this work	-	-	NO
4569756	26421281	Xiao-Yang Liu	2	contributed equally to this work	contributed equally to this work	-	-	NO
4411124	25915643	KS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411124	25915643	NC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411124	25915643	NC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411124	25915643	NC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411124	25915643	NC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411124	25915643	PN	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411124	25915643	PV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411124	25915643	PV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411124	25915643	PV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411124	25915643	PV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411124	25915643	SC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411124	25915643	SG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411124	25915643	SM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411124	25915643	SM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411124	25915643	SM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1829177	17406671	HA	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1829177	17406671	LG	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1829177	17406671	LG	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1829177	17406671	PS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1829177	17406671	PS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1829177	17406671	PS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1829177	17406671	PS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2098780	17919327	CDW	2	participated in the data acquisition, helped in statistical analysis, and helped to draft the manuscript	participated in the data acquisition, helped in statistical analysis, and helped to draft the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
2098780	17919327	DSW	2	conceived the study, developed the study design, secured the funding for the project, helped with statistical analysis, and helped draft the manuscript	conceived the study, developed the study design, secured the funding for the project, helped with statistical analysis, and helped draft the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Funding acquisition|Methodology|Writing - Original Draft	YES
2098780	17919327	JW	2	participated in data acquisition and helped draft the manuscript	participated in data acquisition and helped draft the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
2098780	17919327	LWT	2	participated in the design of the study, coordination and data acquisition, performed the statistical analysis, and drafted the manuscript	participated in the design of the study, coordination and data acquisition, performed the statistical analysis, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Project administration|Writing - Original Draft	YES
2098780	17919327	TH	2	participated in data acquisition and helped to draft the manuscript	participated in data acquisition and helped to draft the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5513398	28716078	BM	2	designed the study|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5513398	28716078	BM	2	designed the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5513398	28716078	JW	2	conceived this study|designed the study|developed the software package|wrote the manuscript	conceived this study	Conceived and designed the experiments	Conceptualization	YES
5513398	28716078	JW	2	conceived this study|designed the study|developed the software package|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5513398	28716078	JW	2	conceived this study|designed the study|developed the software package|wrote the manuscript	developed the software package	Contributed reagents/materials/analysis tools	Software	YES
5513398	28716078	JW	2	conceived this study|designed the study|developed the software package|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5513398	28716078	ON	2	designed the study|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5513398	28716078	ON	2	designed the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5671604	29163589	FF	PLoS5	Data collection|Analyzed the data|Wrote the paper	Data collection	Performed the experiments	Investigation	YES
5671604	29163589	FF	PLoS5	Data collection|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5671604	29163589	FF	PLoS5	Data collection|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5671604	29163589	KS	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5671604	29163589	XQ	PLoS5	Contributed the experimental design|Data collection|Analyzed the data|Wrote the paper	Contributed the experimental design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5671604	29163589	XQ	PLoS5	Contributed the experimental design|Data collection|Analyzed the data|Wrote the paper	Data collection	Performed the experiments	Investigation	YES
5671604	29163589	XQ	PLoS5	Contributed the experimental design|Data collection|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5671604	29163589	XQ	PLoS5	Contributed the experimental design|Data collection|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5671604	29163589	YL	PLoS5	Data collection|Analyzed the data|Wrote the paper	Data collection	Performed the experiments	Investigation	YES
5671604	29163589	YL	PLoS5	Data collection|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5671604	29163589	YL	PLoS5	Data collection|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5671604	29163589	YcL	PLoS5	Contributed the experimental design|Wrote the paper	Contributed the experimental design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5671604	29163589	YcL	PLoS5	Contributed the experimental design|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411125	25915631	AK	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411125	25915631	AK	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411125	25915631	AK	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411125	25915631	EK	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411125	25915631	EZP	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411125	25915631	GKP	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411125	25915631	LAP	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411125	25915631	LAP	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411125	25915631	TCK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4411125	25915631	TCK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411125	25915631	YC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1829178	17389925	CK	PLoS5	Wrote the paper|Contributed to the experimental design and statistical analyses	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1829178	17389925	CK	PLoS5	Wrote the paper|Contributed to the experimental design and statistical analyses	Contributed to the experimental design and statistical analyses	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
1829178	17389925	CW	PLoS5	Wrote the paper|Contributed to the experimental design and statistical analyses	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1829178	17389925	CW	PLoS5	Wrote the paper|Contributed to the experimental design and statistical analyses	Contributed to the experimental design and statistical analyses	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
1829178	17389925	DM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1829178	17389925	DM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1829178	17389925	DM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1829178	17389925	IM	PLoS5	Analyzed the data|Wrote the paper|Assisted in coordination of field studies	Analyzed the data	Analyzed the data	Formal analysis	YES
1829178	17389925	IM	PLoS5	Analyzed the data|Wrote the paper|Assisted in coordination of field studies	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1829178	17389925	IM	PLoS5	Analyzed the data|Wrote the paper|Assisted in coordination of field studies	Assisted in coordination of field studies	-	Project administration	YES
1829178	17389925	JK	PLoS5	Wrote the paper|Contributed to the experimental design	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1829178	17389925	JK	PLoS5	Wrote the paper|Contributed to the experimental design	Contributed to the experimental design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
1829178	17389925	JR	PLoS5	Wrote the paper|Contributed to the experimental design	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1829178	17389925	JR	PLoS5	Wrote the paper|Contributed to the experimental design	Contributed to the experimental design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
1829178	17389925	LK	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Coordinated field studies	Performed the experiments	Performed the experiments	Investigation	YES
1829178	17389925	LK	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Coordinated field studies	Analyzed the data	Analyzed the data	Formal analysis	YES
1829178	17389925	LK	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Coordinated field studies	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1829178	17389925	LK	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Coordinated field studies	Coordinated field studies	-	Project administration	YES
1829178	17389925	PZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Coordinated field and laboratory studies	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1829178	17389925	PZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Coordinated field and laboratory studies	Analyzed the data	Analyzed the data	Formal analysis	YES
1829178	17389925	PZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Coordinated field and laboratory studies	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1829178	17389925	PZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Coordinated field and laboratory studies	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1829178	17389925	PZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Coordinated field and laboratory studies	Coordinated field and laboratory studies	Performed the experiments	Investigation|Project administration	YES
5671605	29163579	DS	2	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5671605	29163579	HO	2	directed the study	directed the study	-	Supervision	YES
5671605	29163579	KI	2	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5671605	29163579	KN	2	directed the study	directed the study	-	Supervision	YES
5671605	29163579	KS	2	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5671605	29163579	MM	2	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5671605	29163579	MS	2	directed the study|designed the experiments|wrote the manuscript	directed the study	-	Supervision	YES
5671605	29163579	MS	2	directed the study|designed the experiments|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5671605	29163579	MS	2	directed the study|designed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5671605	29163579	RS	2	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5671605	29163579	YM	2	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5671605	29163579	YY	2	directed the study|designed the experiments|performed the experiments and analyzed the data|wrote the manuscript	directed the study	-	Supervision	YES
5671605	29163579	YY	2	directed the study|designed the experiments|performed the experiments and analyzed the data|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5671605	29163579	YY	2	directed the study|designed the experiments|performed the experiments and analyzed the data|wrote the manuscript	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5671605	29163579	YY	2	directed the study|designed the experiments|performed the experiments and analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
2100070	17949492	CM	2	participated in the data acquisition	participated in the data acquisition	Performed the experiments	Investigation	YES
2100070	17949492	CW	2	participated in the data acquisition	participated in the data acquisition	Performed the experiments	Investigation	YES
2100070	17949492	DR	2	participated in the design of the study, coordination and data acquisition, and assisted in performing the statistical analysis and drafting the manuscript	participated in the design of the study, coordination and data acquisition, and assisted in performing the statistical analysis and drafting the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Project administration|Writing - Original Draft	YES
2100070	17949492	DSW	2	conceived the study, developed the study design, secured the funding for the project, assisted and provided oversight for all data acquisition and statistical analysis, assisted in drafting the manuscript, and served as the faculty mentor for the project	conceived the study, developed the study design, secured the funding for the project, assisted and provided oversight for all data acquisition and statistical analysis, assisted in drafting the manuscript, and served as the faculty mentor for the project	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Funding acquisition|Investigation|Methodology|Resources|Supervision|Writing - Original Draft	YES
2100070	17949492	LT	2	participated in the data acquisition	participated in the data acquisition	Performed the experiments	Investigation	YES
2100070	17949492	RK	2	participated in the design of the study and assisted in performing the statistical analysis	participated in the design of the study and assisted in performing the statistical analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
4411126	25915652	AT	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411126	25915652	AT	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411126	25915652	AT	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411126	25915652	CRG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411126	25915652	CRG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411126	25915652	CRG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411126	25915652	EE	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411126	25915652	EE	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411126	25915652	EE	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411126	25915652	IJD	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411126	25915652	IJD	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411126	25915652	JMS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411126	25915652	JMS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411126	25915652	JW	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411126	25915652	JW	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411126	25915652	JW	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411126	25915652	MEB	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411126	25915652	MEB	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
551604	15720711	Both authors	2	have read and accepted the final version of the manuscript	have read and accepted the final version of the manuscript	-	-	NO
551604	15720711	JMB	2	built the homology model, analyzed spatial vs	built the homology model, analyzed spatial vs	Performed the experiments|Analyzed the data	Formal analysis|Methodology	YES
551604	15720711	ORFs	2	were regarded as disrupted if they bear frameshift mutations or stop codons	were regarded as disrupted if they bear frameshift mutations or stop codons	-	-	NO
1829190	17406666	EK	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1829190	17406666	EK	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1829190	17406666	KH	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1829190	17406666	KH	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411127	25915550	FC	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411127	25915550	FC	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411127	25915550	JWM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411127	25915550	JWM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411127	25915550	JWM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411127	25915550	JWM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1829191	17389913	DB	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1829191	17389913	DG	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1829191	17389913	DG	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1829191	17389913	DG	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1829191	17389913	DR	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1829191	17389913	DR	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1829191	17389913	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1829191	17389913	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1829191	17389913	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1829191	17389913	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1829191	17389913	KD	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1829191	17389913	LK	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1829191	17389913	LK	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5671638	29163592	AC	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5671638	29163592	All authors	2	participated in the conception of the topic	participated in the conception of the topic	Conceived and designed the experiments	Conceptualization	YES
5671638	29163592	CL	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5671638	29163592	EK	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5671638	29163592	MH	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4569758	26448940	Hongchen Zhang	2	contributed equally to this work	contributed equally to this work	-	-	NO
4569758	26448940	Jian Zhu	2	contributed equally to this work	contributed equally to this work	-	-	NO
5516332	28724407	AMG	2	helped with the transcriptomic and promoter sequence analysis	helped with the transcriptomic and promoter sequence analysis	Performed the experiments	Investigation	YES
5516332	28724407	DN	2	named all genes following the standard p450 nomenclature	named all genes following the standard p450 nomenclature	-	-	NO
5516332	28724407	JA	2	conceived the study and participated in the experimental design and coordination|drafted the manuscript	conceived the study and participated in the experimental design and coordination	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology|Project administration	YES
5516332	28724407	JA	2	conceived the study and participated in the experimental design and coordination|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5516332	28724407	MB	2	contributed to the study design and analysis of the results	contributed to the study design and analysis of the results	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5516332	28724407	MSG	2	helped defining p450 gene structure	helped defining p450 gene structure	-	-	NO
5516332	28724407	PC	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5516332	28724407	VC	2	contributed to the study design and analysis of the results	contributed to the study design and analysis of the results	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
6107617	30126915	A.F.R.	2	developed the quality control method and procedure, led the study design, carried out the data analysis, and drafted the manuscript|contributed model output used in this study	developed the quality control method and procedure, led the study design, carried out the data analysis, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Validation|Writing - Original Draft	YES
6107617	30126915	A.F.R.	2	developed the quality control method and procedure, led the study design, carried out the data analysis, and drafted the manuscript|contributed model output used in this study	contributed model output used in this study	Performed the experiments	Methodology	YES
6107617	30126915	A.P.C.	2	designed and wrote the cice scripting system used for the quality-control testing procedure	designed and wrote the cice scripting system used for the quality-control testing procedure	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Software|Writing - Original Draft	YES
6107617	30126915	All the authors	2	gave their final approval for publication	gave their final approval for publication	-	-	NO
6107617	30126915	D.A.B.	2	contributed model output used in this study	contributed model output used in this study	Performed the experiments	Methodology	YES
6107617	30126915	E.C.H.	2	helped design the study and draft the manuscript|contributed model output used in this study	helped design the study and draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
6107617	30126915	E.C.H.	2	helped design the study and draft the manuscript|contributed model output used in this study	contributed model output used in this study	Performed the experiments	Methodology	YES
6107617	30126915	J.-F.L.	2	contributed model output used in this study	contributed model output used in this study	Performed the experiments	Methodology	YES
6107617	30126915	M.D.T.	2	designed and wrote the cice scripting system used for the quality-control testing procedure	designed and wrote the cice scripting system used for the quality-control testing procedure	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Software|Writing - Original Draft	YES
6107617	30126915	R.A.	2	contributed model output used in this study	contributed model output used in this study	Performed the experiments	Methodology	YES
4411128	25915207	BW	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Proofread the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4411128	25915207	BW	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Proofread the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4411128	25915207	BW	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Proofread the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411128	25915207	BW	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Proofread the manuscript	Proofread the manuscript	-	-	NO
4411128	25915207	FY	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Proofread the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4411128	25915207	FY	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Proofread the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4411128	25915207	FY	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Proofread the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411128	25915207	FY	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Proofread the manuscript	Proofread the manuscript	-	-	NO
4411128	25915207	HP	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Proofread the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411128	25915207	HP	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Proofread the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4411128	25915207	HP	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Proofread the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411128	25915207	HP	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Proofread the manuscript	Proofread the manuscript	-	-	NO
4411128	25915207	KM	PLoS5	Performed the experiments|Analyzed the data|Proofread the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4411128	25915207	KM	PLoS5	Performed the experiments|Analyzed the data|Proofread the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4411128	25915207	KM	PLoS5	Performed the experiments|Analyzed the data|Proofread the manuscript	Proofread the manuscript	-	-	NO
4411128	25915207	LZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Proofread the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411128	25915207	LZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Proofread the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4411128	25915207	LZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Proofread the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411128	25915207	LZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Proofread the manuscript	Proofread the manuscript	-	-	NO
4411128	25915207	XF	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Proofread the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4411128	25915207	XF	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Proofread the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4411128	25915207	XF	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Proofread the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411128	25915207	XF	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Proofread the manuscript	Proofread the manuscript	-	-	NO
4411128	25915207	YZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Proofread the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411128	25915207	YZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Proofread the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4411128	25915207	YZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Proofread the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4411128	25915207	YZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Proofread the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411128	25915207	YZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Proofread the manuscript	Proofread the manuscript	-	-	NO
4411128	25915207	ZT	PLoS5	Conceived and designed the experiments|Wrote the paper|Proofread the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411128	25915207	ZT	PLoS5	Conceived and designed the experiments|Wrote the paper|Proofread the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411128	25915207	ZT	PLoS5	Conceived and designed the experiments|Wrote the paper|Proofread the manuscript	Proofread the manuscript	-	-	NO
2131751	17915021	BS	2	was responsible for the study design and analysis of all performance related variables	was responsible for the study design and analysis of all performance related variables	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
2131751	17915021	MF	2	was responsible for the study design and all data collection	was responsible for the study design and all data collection	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
2131751	17915021	RB	2	was responsible for the study design, biochemical work, statistical analyses, and manuscript preparation	was responsible for the study design, biochemical work, statistical analyses, and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
2131751	17915021	WS	2	was responsible for blood collection, blood processing and biochemical work	was responsible for blood collection, blood processing and biochemical work	Performed the experiments	Investigation	YES
1831490	17406681	AG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Manuscript revision and field work	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1831490	17406681	AG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Manuscript revision and field work	Analyzed the data	Analyzed the data	Formal analysis	YES
1831490	17406681	AG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Manuscript revision and field work	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1831490	17406681	AG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Manuscript revision and field work	Manuscript revision and field work	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
1831490	17406681	CC	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Field work	Performed the experiments	Performed the experiments	Investigation	YES
1831490	17406681	CC	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Field work	Analyzed the data	Analyzed the data	Formal analysis	YES
1831490	17406681	CC	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Field work	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1831490	17406681	CC	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Field work	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1831490	17406681	CC	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Field work	Field work	Performed the experiments	Investigation	YES
1831490	17406681	NP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Manuscript revision and field work	Analyzed the data	Analyzed the data	Formal analysis	YES
1831490	17406681	NP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Manuscript revision and field work	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1831490	17406681	NP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Manuscript revision and field work	Manuscript revision and field work	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
1831490	17406681	RC	PLoS5	Contributed reagents/materials/analysis tools|Ecological and financial support, field work	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1831490	17406681	RC	PLoS5	Contributed reagents/materials/analysis tools|Ecological and financial support, field work	Ecological and financial support, field work	Performed the experiments	Funding acquisition|Investigation	YES
4411129	25915923	AAV	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411129	25915923	DJvV	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411129	25915923	HvdW	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411129	25915923	HvdW	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411129	25915923	ITK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411129	25915923	ITK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411129	25915923	ITK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411129	25915923	ITK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411129	25915923	NGB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411129	25915923	NGB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411129	25915923	NGB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411129	25915923	NV	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411129	25915923	NV	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411129	25915923	PvdH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411129	25915923	PvdH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411129	25915923	PvdH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411129	25915923	PvdM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411129	25915923	PvdM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411129	25915923	PvdM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411129	25915923	RTG	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411129	25915923	SJLB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411129	25915923	SJLB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411129	25915923	SJLB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5516393	28720072	AC	2	performed the qpcr profiling, analysed data and was a major contributor in writing the manuscript|conducted the rna seq bioinformatics	performed the qpcr profiling, analysed data and was a major contributor in writing the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5516393	28720072	AC	2	performed the qpcr profiling, analysed data and was a major contributor in writing the manuscript|conducted the rna seq bioinformatics	conducted the rna seq bioinformatics	Performed the experiments	Formal analysis|Investigation	YES
5516393	28720072	DW	2	analysed data and edited the manuscript	analysed data and edited the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5516393	28720072	EB	2	provided samples and optimised protocols	provided samples and optimised protocols	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Methodology|Resources	YES
5516393	28720072	ESD	2	analysed data and edited the manuscript	analysed data and edited the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5516393	28720072	FAP	2	performed monosaccharide-linkage analysis and acetyl bromide lignin determination, analysed data and was a major contributor in writing the manuscript	performed monosaccharide-linkage analysis and acetyl bromide lignin determination, analysed data and was a major contributor in writing the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5516393	28720072	HB	2	prepared samples for nmr and acetyl bromide lignin determination, analysed data and was a major contributor in writing the manuscript	prepared samples for nmr and acetyl bromide lignin determination, analysed data and was a major contributor in writing the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5516393	28720072	JR	2	performed nmr analysis and contributed to writing the manuscript	performed nmr analysis and contributed to writing the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5516393	28720072	YT	2	performed nmr analysis and contributed to writing the manuscript	performed nmr analysis and contributed to writing the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3833316	24288535	Christine Sorenson	PLoS52	conceived and designed the experiments|prepared the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
3833316	24288535	Christine Sorenson	PLoS52	conceived and designed the experiments|prepared the paper	prepared the paper	Wrote the paper	Writing - Original Draft	YES
3833316	24288535	Margaret Morrison	PLoS52	performed experiments and analyzed data|conceived and designed the experiments	performed experiments and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3833316	24288535	Margaret Morrison	PLoS52	performed experiments and analyzed data|conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
3833316	24288535	Nader Sheibani	PLoS52	conceived and designed the experiments|prepared the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
3833316	24288535	Nader Sheibani	PLoS52	conceived and designed the experiments|prepared the paper	prepared the paper	Wrote the paper	Writing - Original Draft	YES
3833316	24288535	Nasim Jamali	PLoS52	performed experiments and analyzed data|conceived and designed the experiments	performed experiments and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3833316	24288535	Nasim Jamali	PLoS52	performed experiments and analyzed data|conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
3833316	24288535	Tammy L. Palenski	PLoS52	performed experiments and analyzed data|conceived and designed the experiments	performed experiments and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3833316	24288535	Tammy L. Palenski	PLoS52	performed experiments and analyzed data|conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2131752	17931410	DG	2	made contributions to the design, acquisition of data, analysis and interpretation of data and involved in drafting the manuscript and revising	made contributions to the design, acquisition of data, analysis and interpretation of data and involved in drafting the manuscript and revising	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft	YES
2131752	17931410	JC	2	made contributions to the design, acquisition of data, analysis and interpretation of data and involved in drafting the manuscript and revising	made contributions to the design, acquisition of data, analysis and interpretation of data and involved in drafting the manuscript and revising	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft	YES
2131752	17931410	JD	2	made contributions to the design, acquisition of data, analysis and interpretation of data and involved in drafting the manuscript and revising	made contributions to the design, acquisition of data, analysis and interpretation of data and involved in drafting the manuscript and revising	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft	YES
2131752	17931410	RC	2	made contributions to the design, acquisition of data, analysis and interpretation of data and involved in drafting the manuscript and revising	made contributions to the design, acquisition of data, analysis and interpretation of data and involved in drafting the manuscript and revising	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft	YES
5671642	29163590	AA	PLoS52	conceived the project and its components|performed bioinformatics|wrote the paper	conceived the project and its components	Conceived and designed the experiments	Conceptualization	YES
5671642	29163590	AA	PLoS52	conceived the project and its components|performed bioinformatics|wrote the paper	performed bioinformatics	Performed the experiments	Formal analysis|Investigation	YES
5671642	29163590	AA	PLoS52	conceived the project and its components|performed bioinformatics|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5671642	29163590	CB	PLoS52	conceived the project and its components|cloned constructs and performed transient transformations|conducted gene expression analysis|wrote the paper	conceived the project and its components	Conceived and designed the experiments	Conceptualization	YES
5671642	29163590	CB	PLoS52	conceived the project and its components|cloned constructs and performed transient transformations|conducted gene expression analysis|wrote the paper	cloned constructs and performed transient transformations	Performed the experiments	Investigation	YES
5671642	29163590	CB	PLoS52	conceived the project and its components|cloned constructs and performed transient transformations|conducted gene expression analysis|wrote the paper	conducted gene expression analysis	Performed the experiments	Investigation	YES
5671642	29163590	CB	PLoS52	conceived the project and its components|cloned constructs and performed transient transformations|conducted gene expression analysis|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5671642	29163590	KL-W	PLoS52	cloned constructs and performed transient transformations|conducted gene expression analysis	cloned constructs and performed transient transformations	Performed the experiments	Investigation	YES
5671642	29163590	KL-W	PLoS52	cloned constructs and performed transient transformations|conducted gene expression analysis	conducted gene expression analysis	Performed the experiments	Investigation	YES
5671642	29163590	RE	PLoS52	conceived the project and its components|performed bioinformatics|wrote the paper	conceived the project and its components	Conceived and designed the experiments	Conceptualization	YES
5671642	29163590	RE	PLoS52	conceived the project and its components|performed bioinformatics|wrote the paper	performed bioinformatics	Performed the experiments	Formal analysis|Investigation	YES
5671642	29163590	RE	PLoS52	conceived the project and its components|performed bioinformatics|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5671642	29163590	RH	PLoS52	conceived the project and its components	conceived the project and its components	Conceived and designed the experiments	Conceptualization	YES
5671642	29163590	SD	PLoS52	cloned constructs and performed transient transformations	cloned constructs and performed transient transformations	Performed the experiments	Investigation	YES
5671642	29163590	ST	PLoS52	generated pear lines	generated pear lines	Performed the experiments	Investigation	YES
5671642	29163590	TM	PLoS52	grew arabidopsis lines and performed hplc	grew arabidopsis lines and performed hplc	Performed the experiments	Investigation	YES
5671642	29163590	WL	PLoS52	cloned constructs and performed transient transformations|grew arabidopsis lines and performed hplc	cloned constructs and performed transient transformations	Performed the experiments	Investigation	YES
5671642	29163590	WL	PLoS52	cloned constructs and performed transient transformations|grew arabidopsis lines and performed hplc	grew arabidopsis lines and performed hplc	Performed the experiments	Investigation	YES
5671642	29163590	YP	PLoS52	grew arabidopsis lines and performed hplc	grew arabidopsis lines and performed hplc	Performed the experiments	Investigation	YES
4411130	25915414	CY	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4411130	25915414	CY	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4411130	25915414	JY	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411130	25915414	RY	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411130	25915414	XL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411130	25915414	XL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411130	25915414	XL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411130	25915414	XL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411130	25915414	XY	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4411130	25915414	XY	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4411130	25915414	YQ	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411130	25915414	YY	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411131	25915544	ACO	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411131	25915544	ACO	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411131	25915544	ACO	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411131	25915544	ACO	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411131	25915544	AGS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411131	25915544	DLB	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411131	25915544	DLB	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411131	25915544	EGG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411131	25915544	EGG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411131	25915544	EGG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411131	25915544	EGG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411131	25915544	FJBP	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4411131	25915544	HJMG	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4411131	25915544	JLlD	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4411131	25915544	JLlD	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4411131	25915544	RHG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411131	25915544	SFT	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411131	25915544	SFT	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3610212	23514405	JN	2	participated in the design of the experiment|edited the manuscript	participated in the design of the experiment	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3610212	23514405	JN	2	participated in the design of the experiment|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
3610212	23514405	KK	2	participated in the design of the experiment|performed all the experiments, analyzed the data and wrote the manuscript	participated in the design of the experiment	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3610212	23514405	KK	2	participated in the design of the experiment|performed all the experiments, analyzed the data and wrote the manuscript	performed all the experiments, analyzed the data and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
1831491	17406672	DL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1831491	17406672	DL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1831491	17406672	DL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1831491	17406672	DL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5517970	28724357	ADG	PLoS52	performed sequence data processing, analysis and interpretation	performed sequence data processing, analysis and interpretation	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5517970	28724357	ADN	PLoS52	performed medical data analysis, diagnosis cross-validation	performed medical data analysis, diagnosis cross-validation	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Validation	YES
5517970	28724357	AGI	PLoS52	performed phages resistance test	performed phages resistance test	Performed the experiments	Investigation	YES
5517970	28724357	AVK	PLoS52	contributed equally to this work	contributed equally to this work	-	-	NO
5517970	28724357	BJP	PLoS52	performed bacteria cultivation, typing, isolation, samples preparation	performed bacteria cultivation, typing, isolation, samples preparation	Performed the experiments	Investigation	YES
5517970	28724357	BVV	PLoS52	performed dna extraction and sequencing	performed dna extraction and sequencing	Performed the experiments	Investigation	YES
5517970	28724357	DVR	PLoS52	contributed equally to this work|wrote the paper	contributed equally to this work	-	-	NO
5517970	28724357	DVR	PLoS52	contributed equally to this work|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5517970	28724357	GMS	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5517970	28724357	GRB	PLoS52	performed antibiotic susceptibility test and bacteriocin production test	performed antibiotic susceptibility test and bacteriocin production test	Performed the experiments	Investigation	YES
5517970	28724357	GSK	PLoS52	contributed equally to this work|performed sequence data processing, analysis and interpretation|wrote the paper	contributed equally to this work	-	-	NO
5517970	28724357	GSK	PLoS52	contributed equally to this work|performed sequence data processing, analysis and interpretation|wrote the paper	performed sequence data processing, analysis and interpretation	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5517970	28724357	GSK	PLoS52	contributed equally to this work|performed sequence data processing, analysis and interpretation|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5517970	28724357	GVM	PLoS52	supervised the progress of the project|wrote the paper	supervised the progress of the project	-	Supervision	YES
5517970	28724357	GVM	PLoS52	supervised the progress of the project|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5517970	28724357	IRK	PLoS52	performed dna extraction and sequencing	performed dna extraction and sequencing	Performed the experiments	Investigation	YES
5517970	28724357	KAV	PLoS52	performed sequence data processing, analysis and interpretation|wrote the paper	performed sequence data processing, analysis and interpretation	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5517970	28724357	KAV	PLoS52	performed sequence data processing, analysis and interpretation|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5517970	28724357	KES	PLoS52	performed dna extraction and sequencing	performed dna extraction and sequencing	Performed the experiments	Investigation	YES
5517970	28724357	KIL	PLoS52	performed endoscopy, samples acquisition, data collecting, diagnostics	performed endoscopy, samples acquisition, data collecting, diagnostics	Performed the experiments	Investigation	YES
5517970	28724357	KIY	PLoS52	performed dna extraction and sequencing	performed dna extraction and sequencing	Performed the experiments	Investigation	YES
5517970	28724357	LAK	PLoS52	performed dna extraction and sequencing	performed dna extraction and sequencing	Performed the experiments	Investigation	YES
5517970	28724357	LES	PLoS52	performed antibiotic susceptibility test and bacteriocin production test	performed antibiotic susceptibility test and bacteriocin production test	Performed the experiments	Investigation	YES
5517970	28724357	LVG	PLoS52	performed bacteria cultivation, typing, isolation, samples preparation	performed bacteria cultivation, typing, isolation, samples preparation	Performed the experiments	Investigation	YES
5517970	28724357	MAI	PLoS52	contributed equally to this work|performed sequence data processing, analysis and interpretation|wrote the paper	contributed equally to this work	-	-	NO
5517970	28724357	MAI	PLoS52	contributed equally to this work|performed sequence data processing, analysis and interpretation|wrote the paper	performed sequence data processing, analysis and interpretation	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5517970	28724357	MAI	PLoS52	contributed equally to this work|performed sequence data processing, analysis and interpretation|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5517970	28724357	MIV	PLoS52	performed medical data analysis, diagnosis cross-validation	performed medical data analysis, diagnosis cross-validation	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Validation	YES
5517970	28724357	MSY	PLoS52	performed dna extraction and sequencing	performed dna extraction and sequencing	Performed the experiments	Investigation	YES
5517970	28724357	PL	PLoS52	performed endoscopy, samples acquisition, data collecting, diagnostics	performed endoscopy, samples acquisition, data collecting, diagnostics	Performed the experiments	Investigation	YES
5517970	28724357	RDV	PLoS52	performed bacteria cultivation, typing, isolation, samples preparation	performed bacteria cultivation, typing, isolation, samples preparation	Performed the experiments	Investigation	YES
5517970	28724357	SMV	PLoS52	performed endoscopy, samples acquisition, data collecting, diagnostics	performed endoscopy, samples acquisition, data collecting, diagnostics	Performed the experiments	Investigation	YES
5517970	28724357	STA	PLoS52	performed dna extraction and sequencing	performed dna extraction and sequencing	Performed the experiments	Investigation	YES
5671643	29163599	THK	2	conceived the idea and wrote the paper	conceived the idea and wrote the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
6107620	30126918	The authors	2	contributed equally to all parts of the paper	contributed equally to all parts of the paper	-	-	NO
4411132	25915798	ALJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411132	25915798	ALJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411132	25915798	ALJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411132	25915798	ALJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411132	25915798	BSD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411132	25915798	BSD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411132	25915798	BSD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411132	25915798	BSD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411132	25915798	ENP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411132	25915798	JDD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411132	25915798	JDD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411132	25915798	JDD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411132	25915798	LVN	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411132	25915798	PCC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411132	25915798	RAJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411132	25915798	RAJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411132	25915798	RAJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411132	25915798	RAJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411132	25915798	SMMH	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411132	25915798	SMMH	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4569764	26421307	All the authors	2	contributed equally to this work	contributed equally to this work	-	-	NO
2164944	17974033	IBS	2	conducted the laboratory testing, physiological data analysis and drafted the manuscript	conducted the laboratory testing, physiological data analysis and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
2164944	17974033	KLS	2	conducted the nutritional data analysis and contributed to the manuscript	conducted the nutritional data analysis and contributed to the manuscript	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
1831492	17406683	AP	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1831492	17406683	CO	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1831492	17406683	DL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1831492	17406683	DS	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1831492	17406683	GS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1831492	17406683	HS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1831492	17406683	JH	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1831492	17406683	JJ	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1831492	17406683	JK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1831492	17406683	JR	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1831492	17406683	NC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1831492	17406683	NK	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1831492	17406683	PG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1831492	17406683	PS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1831492	17406683	VL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1831492	17406683	VL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1831492	17406683	VN	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1831492	17406683	VW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5671653	29163598	DW	2	analyzed the rna seq data	analyzed the rna seq data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5671653	29163598	GR	2	analyzed the rna seq data	analyzed the rna seq data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5671653	29163598	HZ	2	performed the experiment	performed the experiment	Performed the experiments	Investigation	YES
5671653	29163598	JC	2	conceived and designed the experiment|revised the manuscript	conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5671653	29163598	JC	2	conceived and designed the experiment|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5671653	29163598	JH	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5671653	29163598	MB	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5671653	29163598	RL	2	performed the experiment|analyzed the rna seq data|wrote the manuscript	performed the experiment	Performed the experiments	Investigation	YES
5671653	29163598	RL	2	performed the experiment|analyzed the rna seq data|wrote the manuscript	analyzed the rna seq data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5671653	29163598	RL	2	performed the experiment|analyzed the rna seq data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5671653	29163598	TY	2	conceived and designed the experiment|performed the experiment|analyzed the rna seq data|wrote the manuscript	conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5671653	29163598	TY	2	conceived and designed the experiment|performed the experiment|analyzed the rna seq data|wrote the manuscript	performed the experiment	Performed the experiments	Investigation	YES
5671653	29163598	TY	2	conceived and designed the experiment|performed the experiment|analyzed the rna seq data|wrote the manuscript	analyzed the rna seq data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5671653	29163598	TY	2	conceived and designed the experiment|performed the experiment|analyzed the rna seq data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5671653	29163598	XH	2	conceived and designed the experiment|performed the experiment|analyzed the rna seq data|wrote the manuscript	conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5671653	29163598	XH	2	conceived and designed the experiment|performed the experiment|analyzed the rna seq data|wrote the manuscript	performed the experiment	Performed the experiments	Investigation	YES
5671653	29163598	XH	2	conceived and designed the experiment|performed the experiment|analyzed the rna seq data|wrote the manuscript	analyzed the rna seq data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5671653	29163598	XH	2	conceived and designed the experiment|performed the experiment|analyzed the rna seq data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5671653	29163598	XZ	2	conceived and designed the experiment|revised the manuscript	conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5671653	29163598	XZ	2	conceived and designed the experiment|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5671653	29163598	YW	2	performed the experiment	performed the experiment	Performed the experiments	Investigation	YES
5671653	29163598	YY	2	analyzed the rna seq data	analyzed the rna seq data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5518114	28724354	All the authors	2	participated in data interpretation, and read and approved the manuscript	participated in data interpretation, and read and approved the manuscript	Analyzed the data	Formal analysis	YES
5518114	28724354	JG	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5518114	28724354	JP	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5518114	28724354	MC	2	designed the study|curated the model and performed metabolic network, statistical, and machine learning analyses	designed the study	Conceived and designed the experiments	Methodology	YES
5518114	28724354	MC	2	designed the study|curated the model and performed metabolic network, statistical, and machine learning analyses	curated the model and performed metabolic network, statistical, and machine learning analyses	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation|Methodology	YES
3627625	23547945	DK	PLoS52	designed research	designed research	Conceived and designed the experiments	Methodology	YES
3627625	23547945	HH	PLoS52	designed research|performed research|analyzed data|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
3627625	23547945	HH	PLoS52	designed research|performed research|analyzed data|wrote the paper	performed research	Performed the experiments	Investigation	YES
3627625	23547945	HH	PLoS52	designed research|performed research|analyzed data|wrote the paper	analyzed data	Analyzed the data	Formal analysis	YES
3627625	23547945	HH	PLoS52	designed research|performed research|analyzed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3627625	23547945	KM	PLoS52	designed research	designed research	Conceived and designed the experiments	Methodology	YES
3627625	23547945	NM	PLoS52	designed research	designed research	Conceived and designed the experiments	Methodology	YES
3627625	23547945	SS	PLoS52	performed research|analyzed data|wrote the paper	performed research	Performed the experiments	Investigation	YES
3627625	23547945	SS	PLoS52	performed research|analyzed data|wrote the paper	analyzed data	Analyzed the data	Formal analysis	YES
3627625	23547945	SS	PLoS52	performed research|analyzed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3627625	23547945	TY	PLoS52	designed research|performed research|analyzed data	designed research	Conceived and designed the experiments	Methodology	YES
3627625	23547945	TY	PLoS52	designed research|performed research|analyzed data	performed research	Performed the experiments	Investigation	YES
3627625	23547945	TY	PLoS52	designed research|performed research|analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
4411133	25915489	AC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4411133	25915489	AC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411133	25915489	AL	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411133	25915489	AL	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411133	25915489	BBN	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411133	25915489	BBN	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411133	25915489	BP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4411133	25915489	BP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411133	25915489	FF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411133	25915489	FF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411133	25915489	FF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411133	25915489	GL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411133	25915489	LP	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411133	25915489	LP	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411133	25915489	RS	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6107621	30126908	M.H.M.	2	developed the computer codes	developed the computer codes	Contributed reagents/materials/analysis tools	Formal analysis|Software	YES
6107621	30126908	The authors	2	jointly conceived of and wrote the paper	jointly conceived of and wrote the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
2174513	17956623	CK	2	participated in the data acquisition	participated in the data acquisition	Performed the experiments	Investigation	YES
2174513	17956623	CM	2	participated in the design of the study, coordination and data acquisition, and assisted in performing the statistical analysis and drafting the manuscript	participated in the design of the study, coordination and data acquisition, and assisted in performing the statistical analysis and drafting the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Project administration|Writing - Original Draft	YES
2174513	17956623	DSW	2	conceived the study, developed the study design, secured the funding for the project, assisted and provided oversight for all data acquisition and statistical analysis, assisted in drafting the manuscript, and served as the faculty mentor for the project	conceived the study, developed the study design, secured the funding for the project, assisted and provided oversight for all data acquisition and statistical analysis, assisted in drafting the manuscript, and served as the faculty mentor for the project	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Funding acquisition|Investigation|Methodology|Resources|Supervision|Writing - Original Draft	YES
2174513	17956623	EN	2	participated in the design of the study, coordination and data acquisition, and assisted in performing the statistical analysis and drafting the manuscript	participated in the design of the study, coordination and data acquisition, and assisted in performing the statistical analysis and drafting the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Project administration|Writing - Original Draft	YES
2174513	17956623	LT	2	participated in the data acquisition	participated in the data acquisition	Performed the experiments	Investigation	YES
2174513	17956623	MG	2	participated in the data acquisition|participated in the design of the study and assisted in performing the statistical analysis	participated in the data acquisition	Performed the experiments	Investigation	YES
2174513	17956623	MG	2	participated in the data acquisition|participated in the design of the study and assisted in performing the statistical analysis	participated in the design of the study and assisted in performing the statistical analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
2174513	17956623	RK	2	assisted with the design of the study, in securing funding for the project, and in the statistical analysis	assisted with the design of the study, in securing funding for the project, and in the statistical analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Funding acquisition|Methodology	YES
1831493	17406674	GD	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1831493	17406674	GD	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1831493	17406674	GD	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1831493	17406674	GG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1831493	17406674	GG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1831493	17406674	GG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1831493	17406674	PB	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1831493	17406674	RT	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1831493	17406674	RT	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1831493	17406674	RT	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1831493	17406674	SA	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1831493	17406674	SA	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1831493	17406674	VP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5671667	29163605	DQ	2	designed experiments	designed experiments	Conceived and designed the experiments	Methodology	YES
5671667	29163605	JY	2	assist the experiments	assist the experiments	Performed the experiments	Investigation	YES
5671667	29163605	XY	2	designed experiments	designed experiments	Conceived and designed the experiments	Methodology	YES
5671667	29163605	YD	2	assist the experiments	assist the experiments	Performed the experiments	Investigation	YES
5671667	29163605	YG	2	analyzed experimental results	analyzed experimental results	Analyzed the data	Formal analysis	YES
5671667	29163605	YL	2	assist the experiments	assist the experiments	Performed the experiments	Investigation	YES
5671667	29163605	YZ	2	carried out experiments and wrote the manuscript	carried out experiments and wrote the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4569774	26421302	Dong Wang	2	performed the experiments related to gender differences in smc plasticity and edited the paper	performed the experiments related to gender differences in smc plasticity and edited the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4569774	26421302	Elie Fadel	2	designed the studies and edited the paper	designed the studies and edited the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
4569774	26421302	Hermann Reichenspurner	2	designed the studies and edited the paper	designed the studies and edited the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
4569774	26421302	Julien Guihaire	2	performed the experiments, analyzed the data, and wrote the paper	performed the experiments, analyzed the data, and wrote the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4569774	26421302	Sonja Schrepfer	2	designed the studies, secured the funding, analyzed the data, and wrote the paper	designed the studies, secured the funding, analyzed the data, and wrote the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Funding acquisition|Methodology|Writing - Original Draft	YES
4569774	26421302	Tobias Deuse	2	designed the studies and wrote the paper	designed the studies and wrote the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5518130	28724410	BSX	2	provided guidance on the experimental design and funding	provided guidance on the experimental design and funding	Conceived and designed the experiments	Funding acquisition|Methodology|Supervision	YES
5518130	28724410	BWG	2	gathered the samples	gathered the samples	-	-	NO
5518130	28724410	CJL	2	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5518130	28724410	JFC	2	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5518130	28724410	JQZ	2	gathered the samples	gathered the samples	-	-	NO
5518130	28724410	JW	2	designed the experiments|gathered the samples|performed the data analysis, interpreted the results, and drafted the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5518130	28724410	JW	2	designed the experiments|gathered the samples|performed the data analysis, interpreted the results, and drafted the manuscript	gathered the samples	-	-	NO
5518130	28724410	JW	2	designed the experiments|gathered the samples|performed the data analysis, interpreted the results, and drafted the manuscript	performed the data analysis, interpreted the results, and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5518130	28724410	LSH	2	participated in intellectual discussions	participated in intellectual discussions	-	-	NO
5518130	28724410	WDS	2	provided guidance on the experimental design and funding	provided guidance on the experimental design and funding	Conceived and designed the experiments	Funding acquisition|Methodology|Supervision	YES
5518130	28724410	XXB	2	participated in intellectual discussions	participated in intellectual discussions	-	-	NO
5518130	28724410	YG	2	participated in intellectual discussions	participated in intellectual discussions	-	-	NO
5518130	28724410	ZHS	2	participated in intellectual discussions	participated in intellectual discussions	-	-	NO
6107622	30126920	D.L.F.	2	provided expert knowledge and experimental direction	provided expert knowledge and experimental direction	-	-	NO
6107622	30126920	H.D.B.S.H.	2	adapted the cice model, designed and carried out the experiments, performed the data analysis and drafted the manuscript	adapted the cice model, designed and carried out the experiments, performed the data analysis and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
6107622	30126920	M.T.	2	performed preliminary experiments and model development	performed preliminary experiments and model development	Performed the experiments	Investigation|Methodology	YES
2206055	17997838	MF	2	analyzed the results statistically|performed the pharmacokinetic analysis of the data, and|drafted the manuscript	analyzed the results statistically	Analyzed the data	Formal analysis	YES
2206055	17997838	MF	2	analyzed the results statistically|performed the pharmacokinetic analysis of the data, and|drafted the manuscript	performed the pharmacokinetic analysis of the data, and	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
2206055	17997838	MF	2	analyzed the results statistically|performed the pharmacokinetic analysis of the data, and|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
2206055	17997838	MP	2	participated in the design of the study	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
2206055	17997838	RH	2	participated in the design of the study|drafted the manuscript	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
2206055	17997838	RH	2	participated in the design of the study|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
2206055	17997838	RJ	2	participated in the design of the study|drafted the manuscript	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
2206055	17997838	RJ	2	participated in the design of the study|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4411134	25915866	JEL	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4411134	25915866	JEL	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4411134	25915866	JKV	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411134	25915866	JKV	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411134	25915866	JKV	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411134	25915866	MAG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411134	25915866	MAG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411134	25915866	MAG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411134	25915866	MAG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411134	25915866	PS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411134	25915866	PS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411134	25915866	PS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411134	25915866	PS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411134	25915866	SJS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411134	25915866	SJS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4411134	25915866	SJS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411134	25915866	WAA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411134	25915866	WAA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411134	25915866	WAA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411134	25915866	WAA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411134	25915866	WAA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1831494	17406673	AG	PLoS5	Initiated the research, obtained the datasets and wrote the outline of the paper	Initiated the research, obtained the datasets and wrote the outline of the paper	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
1831494	17406673	PC	PLoS5	Developed the statistical methods for calculating the confidence intervals	Developed the statistical methods for calculating the confidence intervals	Performed the experiments|Analyzed the data	Formal analysis|Methodology	YES
1831494	17406673	TG	PLoS5	Analyzed the data|Programmed and performed the data analysis and wrote the first draft of the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1831494	17406673	TG	PLoS5	Analyzed the data|Programmed and performed the data analysis and wrote the first draft of the paper	Programmed and performed the data analysis and wrote the first draft of the paper	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Software|Writing - Original Draft	YES
5671996	29163608	CL	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
5671996	29163608	CL	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5671996	29163608	DR	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5671996	29163608	GC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote and revised the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5671996	29163608	GC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote and revised the paper	Performed the experiments	Performed the experiments	Investigation	YES
5671996	29163608	GC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote and revised the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5671996	29163608	GC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote and revised the paper	Wrote and revised the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5671996	29163608	GX	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote and revised the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5671996	29163608	GX	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote and revised the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5671996	29163608	GX	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote and revised the paper	Wrote and revised the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5671996	29163608	HJ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5671996	29163608	LY	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5671996	29163608	LZ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5671996	29163608	QQ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote and revised the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5671996	29163608	QQ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote and revised the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5671996	29163608	QQ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote and revised the paper	Wrote and revised the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5671996	29163608	YZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5671996	29163608	ZG	PLoS5	Analyzed the data|Wrote and revised the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5671996	29163608	ZG	PLoS5	Analyzed the data|Wrote and revised the paper	Wrote and revised the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3671168	23659479	HK	2	designed the experiment, analyzed the data and drafted the manuscript|performed experiments and collected data	designed the experiment, analyzed the data and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3671168	23659479	HK	2	designed the experiment, analyzed the data and drafted the manuscript|performed experiments and collected data	performed experiments and collected data	Performed the experiments	Investigation	YES
3671168	23659479	SNG	2	designed the experiment, analyzed the data and drafted the manuscript	designed the experiment, analyzed the data and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3671168	23659479	SNM	2	designed the experiment, analyzed the data and drafted the manuscript|performed experiments and collected data	designed the experiment, analyzed the data and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3671168	23659479	SNM	2	designed the experiment, analyzed the data and drafted the manuscript|performed experiments and collected data	performed experiments and collected data	Performed the experiments	Investigation	YES
5518131	28724409	BW	4	Analysis and manuscript by	Analysis and manuscript by	-	-	NO
5518131	28724409	HL	4	Rice sequencing and ECTools development by	Rice sequencing and ECTools development by	Performed the experiments	Investigation	YES
5518131	28724409	JG	4	Rice sequencing and ECTools development by	Rice sequencing and ECTools development by	Performed the experiments	Investigation	YES
5518131	28724409	JL	4	Medicago sequencing by	Medicago sequencing by	Performed the experiments	Investigation	YES
5518131	28724409	JM	4	Medicago sequencing by|Analysis and manuscript by	Medicago sequencing by	Performed the experiments	Investigation	YES
5518131	28724409	JM	4	Medicago sequencing by|Analysis and manuscript by	Analysis and manuscript by	-	-	NO
5518131	28724409	JRM	4	Analysis and manuscript by	Analysis and manuscript by	-	-	NO
5518131	28724409	KATS	4	Medicago sequencing by|Analysis and manuscript by	Medicago sequencing by	Performed the experiments	Investigation	YES
5518131	28724409	KATS	4	Medicago sequencing by|Analysis and manuscript by	Analysis and manuscript by	-	-	NO
5518131	28724409	LGM	4	Rice sequencing and ECTools development by	Rice sequencing and ECTools development by	Performed the experiments	Investigation	YES
5518131	28724409	LS	4	Analysis and manuscript by	Analysis and manuscript by	-	-	NO
5518131	28724409	MCS	4	Rice sequencing and ECTools development by|Analysis and manuscript by	Rice sequencing and ECTools development by	Performed the experiments	Investigation	YES
5518131	28724409	MCS	4	Rice sequencing and ECTools development by|Analysis and manuscript by	Analysis and manuscript by	-	-	NO
5518131	28724409	NS	4	Rice sequencing and ECTools development by	Rice sequencing and ECTools development by	Performed the experiments	Investigation	YES
5518131	28724409	NY	4	Medicago sequencing by|Analysis and manuscript by	Medicago sequencing by	Performed the experiments	Investigation	YES
5518131	28724409	NY	4	Medicago sequencing by|Analysis and manuscript by	Analysis and manuscript by	-	-	NO
5518131	28724409	PT	4	Analysis and manuscript by	Analysis and manuscript by	-	-	NO
5518131	28724409	PZ	4	Analysis and manuscript by	Analysis and manuscript by	-	-	NO
5518131	28724409	RD	4	Medicago sequencing by	Medicago sequencing by	Performed the experiments	Investigation	YES
5518131	28724409	RS	4	Medicago sequencing by	Medicago sequencing by	Performed the experiments	Investigation	YES
5518131	28724409	SRM	4	Rice sequencing and ECTools development by	Rice sequencing and ECTools development by	Performed the experiments	Investigation	YES
5518131	28724409	TR	4	Medicago sequencing by|Analysis and manuscript by	Medicago sequencing by	Performed the experiments	Investigation	YES
5518131	28724409	TR	4	Medicago sequencing by|Analysis and manuscript by	Analysis and manuscript by	-	-	NO
5518131	28724409	WRM	4	Rice sequencing and ECTools development by	Rice sequencing and ECTools development by	Performed the experiments	Investigation	YES
3164220	21892258	All authors	PLoS52	contributed to drafting and critically revising the manuscript	contributed to drafting and critically revising the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3164220	21892258	HEW	PLoS52	conceived and designed the study|analyzed the data	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3164220	21892258	HEW	PLoS52	conceived and designed the study|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
3164220	21892258	MPM	PLoS52	conceived and designed the study|analyzed the data	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3164220	21892258	MPM	PLoS52	conceived and designed the study|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
3164220	21892258	PGT	PLoS52	carried out the study and collected data|analyzed the data	carried out the study and collected data	Performed the experiments	Investigation	YES
3164220	21892258	PGT	PLoS52	carried out the study and collected data|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
6127380	30177560	A.J.P.	2	contributed to data collection, analysis and interpretation	contributed to data collection, analysis and interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6127380	30177560	P.R.B.	2	contributed to data collection, analysis and interpretation|drafted the manuscript	contributed to data collection, analysis and interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6127380	30177560	P.R.B.	2	contributed to data collection, analysis and interpretation|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
6127380	30177560	R.M.S.	2	developed the methodology and performed the majority of the data collection and analysis|drafted the manuscript	developed the methodology and performed the majority of the data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
6127380	30177560	R.M.S.	2	developed the methodology and performed the majority of the data collection and analysis|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
6127380	30177560	S.A.A.	2	contributed to data collection, analysis and interpretation	contributed to data collection, analysis and interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6127380	30177560	S.J.G.	2	conceived of and designed the study|developed the methodology and performed the majority of the data collection and analysis|drafted the manuscript	conceived of and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6127380	30177560	S.J.G.	2	conceived of and designed the study|developed the methodology and performed the majority of the data collection and analysis|drafted the manuscript	developed the methodology and performed the majority of the data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
6127380	30177560	S.J.G.	2	conceived of and designed the study|developed the methodology and performed the majority of the data collection and analysis|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
2206056	17997840	ALA	7	Research design, assisted in obtaining grant funding, data analysis	Research design, assisted in obtaining grant funding, data analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Funding acquisition|Investigation	YES
2206056	17997840	CE	7	Data analysis and manuscript preparation	Data analysis and manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
2206056	17997840	CR	7	Lab director, data collection	Lab director, data collection	Performed the experiments	Investigation	YES
2206056	17997840	JL	7	Study coordinator and data collection	Study coordinator and data collection	Performed the experiments	Investigation|Project administration	YES
2206056	17997840	MG	7	Data collection and analysis	Data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
2206056	17997840	PC	7	Medical supervision and data collection	Medical supervision and data collection	Performed the experiments	Investigation|Supervision	YES
2206056	17997840	RBK	7	Obtained grant, served as PI of study, data analysis, manuscript preparation	Obtained grant, served as PI of study, data analysis, manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Funding acquisition|Investigation|Writing - Original Draft	YES
3671206	23657221	DHEC	PLoS52	participated in the design of the experiment|performed all the experiments|analyzed the data|wrote the manuscript	participated in the design of the experiment	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3671206	23657221	DHEC	PLoS52	participated in the design of the experiment|performed all the experiments|analyzed the data|wrote the manuscript	performed all the experiments	Performed the experiments	Investigation	YES
3671206	23657221	DHEC	PLoS52	participated in the design of the experiment|performed all the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
3671206	23657221	DHEC	PLoS52	participated in the design of the experiment|performed all the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3671206	23657221	KS	PLoS52	participated in the design of the experiment|analyzed the data|edited the manuscript	participated in the design of the experiment	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3671206	23657221	KS	PLoS52	participated in the design of the experiment|analyzed the data|edited the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
3671206	23657221	KS	PLoS52	participated in the design of the experiment|analyzed the data|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
4411135	25915941	ATC	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411135	25915941	ATC	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411135	25915941	BNP	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411135	25915941	BNP	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411135	25915941	BNP	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411135	25915941	LGM	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411135	25915941	LGM	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411135	25915941	MSL	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411135	25915941	MSL	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411135	25915941	MSL	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411135	25915941	MSL	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411135	25915941	NAP	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411135	25915941	NAP	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411135	25915941	NAP	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411135	25915941	VMV	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411135	25915941	VMV	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411135	25915941	VMV	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5672016	29163583	All authors	2	listed have made a substantial, direct and intellectual contribution to the work, and approved it for publication	listed have made a substantial, direct and intellectual contribution to the work, and approved it for publication	-	-	NO
1831495	17406675	CW	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1831495	17406675	EW	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1831495	17406675	GL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1831495	17406675	GL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1831495	17406675	GL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1831495	17406675	GL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1831495	17406675	JK	PLoS5	Performed the experiments|Analyzed the data|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1831495	17406675	JK	PLoS5	Performed the experiments|Analyzed the data|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1831495	17406675	JK	PLoS5	Performed the experiments|Analyzed the data|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1831495	17406675	JP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1831495	17406675	JP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1831495	17406675	JP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1831495	17406675	JP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1831495	17406675	KJ	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1831495	17406675	QC	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4571527	26421297	Dongdong Zhang	2	were involved in ovary histological analysis	were involved in ovary histological analysis	Performed the experiments	Investigation	YES
4571527	26421297	Hengxi Wei	2	contributed equally to the work|contributed to data collection and paper drafting	contributed equally to the work	-	-	NO
4571527	26421297	Hengxi Wei	2	contributed equally to the work|contributed to data collection and paper drafting	contributed to data collection and paper drafting	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4571527	26421297	Jihong Yuan	2	were involved in ovary histological analysis	were involved in ovary histological analysis	Performed the experiments	Investigation	YES
4571527	26421297	Li Li	2	contributed to data analysis and statistics	contributed to data analysis and statistics	Analyzed the data	Formal analysis	YES
4571527	26421297	Lin Liu	2	contributed to revising the paper	contributed to revising the paper	Wrote the paper	Writing - Review & Editing	YES
4571527	26421297	Shouquan Zhang	2	contributed to study concept and design	contributed to study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4571527	26421297	Xiangjie Liu	2	contributed equally to the work|contributed to data collection and paper drafting	contributed equally to the work	-	-	NO
4571527	26421297	Xiangjie Liu	2	contributed equally to the work|contributed to data collection and paper drafting	contributed to data collection and paper drafting	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4571527	26421297	Xinzheng Guo	2	contributed to data analysis and statistics	contributed to data analysis and statistics	Analyzed the data	Formal analysis	YES
5518132	28724352	GJ	2	designed the study, analyzed the results and wrote the manuscript|implemented the algorithm	designed the study, analyzed the results and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5518132	28724352	GJ	2	designed the study, analyzed the results and wrote the manuscript|implemented the algorithm	implemented the algorithm	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5518132	28724352	GX	2	designed the study, analyzed the results and wrote the manuscript	designed the study, analyzed the results and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5518132	28724352	XW	2	designed the study, analyzed the results and wrote the manuscript	designed the study, analyzed the results and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
2211291	18053183	KFW	2	was responsible for data collection, blood collection and processing, and manuscript preparation	was responsible for data collection, blood collection and processing, and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Investigation|Writing - Original Draft	YES
2211291	18053183	RB	2	was responsible for the study design, biochemical work, statistical analyses, and manuscript preparation	was responsible for the study design, biochemical work, statistical analyses, and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
2211291	18053183	WS	2	was responsible for the study design, data collection, blood collection and processing, and manuscript preparation	was responsible for the study design, data collection, blood collection and processing, and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Investigation|Methodology|Writing - Original Draft	YES
4411136	25915772	DLJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411136	25915772	DLJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411136	25915772	DLJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411136	25915772	FS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411136	25915772	FS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411136	25915772	FS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411136	25915772	LS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411136	25915772	LS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411136	25915772	LS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411136	25915772	PC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411136	25915772	PC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411136	25915772	PC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411136	25915772	RA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411136	25915772	RA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411136	25915772	RA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411136	25915772	RG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411136	25915772	RG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411136	25915772	RG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411136	25915772	RN	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411136	25915772	RN	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411136	25915772	RN	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411136	25915772	TA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411136	25915772	TA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411136	25915772	TA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1831496	17406677	AH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1831496	17406677	AH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1831496	17406677	AH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1831496	17406677	GB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1831496	17406677	GB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1831496	17406677	GB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1831496	17406677	GB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1831496	17406677	HS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1831496	17406677	HS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1831496	17406677	HS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1831496	17406677	SX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1831496	17406677	SX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1831496	17406677	SX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5672021	29163600	LF	2	conceived and designed the experiment, collected the materials, and wrote the paper|performed the experiments, assembled sequences, and analyzed the data	conceived and designed the experiment, collected the materials, and wrote the paper	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Writing - Original Draft	YES
5672021	29163600	LF	2	conceived and designed the experiment, collected the materials, and wrote the paper|performed the experiments, assembled sequences, and analyzed the data	performed the experiments, assembled sequences, and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5672021	29163600	LL	2	conceived and designed the experiment, collected the materials, and wrote the paper	conceived and designed the experiment, collected the materials, and wrote the paper	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Writing - Original Draft	YES
6127389	30177568	A.R.	2	carried out the modelling	carried out the modelling	Performed the experiments	Investigation|Methodology	YES
6127389	30177568	All authors	2	gave final approval for publication	gave final approval for publication	-	-	NO
6127389	30177568	D.N.S.	2	conceived and designed the study|conducted the data analysis|interpreted the data and wrote the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6127389	30177568	D.N.S.	2	conceived and designed the study|conducted the data analysis|interpreted the data and wrote the manuscript	conducted the data analysis	Analyzed the data	Formal analysis	YES
6127389	30177568	D.N.S.	2	conceived and designed the study|conducted the data analysis|interpreted the data and wrote the manuscript	interpreted the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6127389	30177568	D.S.	2	carried out the laboratory work	carried out the laboratory work	Performed the experiments	Investigation	YES
6127389	30177568	E.A.	2	carried out the laboratory work|conducted the data analysis	carried out the laboratory work	Performed the experiments	Investigation	YES
6127389	30177568	E.A.	2	carried out the laboratory work|conducted the data analysis	conducted the data analysis	Analyzed the data	Formal analysis	YES
6127389	30177568	E.T.	2	interpreted the data and wrote the manuscript	interpreted the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5520234	28728575	DC	2	were involved in the development of the association mapping population|performed phenotypic analysis	were involved in the development of the association mapping population	-	-	NO
5520234	28728575	DC	2	were involved in the development of the association mapping population|performed phenotypic analysis	performed phenotypic analysis	Performed the experiments	Investigation	YES
5520234	28728575	DN	2	conceived the study and designed the experiments	conceived the study and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5520234	28728575	IC	2	conceived the study and designed the experiments	conceived the study and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5520234	28728575	JK	2	conceived the study and designed the experiments|were involved in the development of the association mapping population|performed phenotypic analysis	conceived the study and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5520234	28728575	JK	2	conceived the study and designed the experiments|were involved in the development of the association mapping population|performed phenotypic analysis	were involved in the development of the association mapping population	-	-	NO
5520234	28728575	JK	2	conceived the study and designed the experiments|were involved in the development of the association mapping population|performed phenotypic analysis	performed phenotypic analysis	Performed the experiments	Investigation	YES
4411137	25915649	BL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411137	25915649	CJL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411137	25915649	HR	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411137	25915649	J. Liang	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411137	25915649	J. Liu	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411137	25915649	LGJ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411137	25915649	LGJ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411137	25915649	LGJ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411137	25915649	MYL	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411137	25915649	QYZ	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411137	25915649	QYZ	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411137	25915649	RZZ	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411137	25915649	RZZ	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411137	25915649	SM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
3863542	24369467	A. Senatore	2	contributed equally to this work	contributed equally to this work	-	-	NO
3863542	24369467	E. Restelli	2	contributed equally to this work	contributed equally to this work	-	-	NO
1831497	17406678	AR	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1831497	17406678	AR	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1831497	17406678	MF	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1831497	17406678	MF	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1831497	17406678	MF	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411138	25915410	CZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411138	25915410	CZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411138	25915410	CZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411138	25915410	JL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4411138	25915410	JL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411138	25915410	KL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411138	25915410	LF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411138	25915410	LF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411138	25915410	LF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411138	25915410	LF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411138	25915410	QC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411138	25915410	SZ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411138	25915410	WH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411138	25915410	WH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411138	25915410	WH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411138	25915410	XC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5672332	29163556	BH	2	contributed to data analyses and discussion	contributed to data analyses and discussion	Analyzed the data	Formal analysis	YES
5672332	29163556	GY	2	designed the experiments, analyzed the data and wrote the manuscript	designed the experiments, analyzed the data and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5672332	29163556	HL	2	contributed to data analyses and discussion	contributed to data analyses and discussion	Analyzed the data	Formal analysis	YES
5672332	29163556	HW	2	contributed in the stress experiments	contributed in the stress experiments	Performed the experiments	Investigation	YES
5672332	29163556	HZ	2	contributed in the stress experiments	contributed in the stress experiments	Performed the experiments	Investigation	YES
5672332	29163556	LZ	2	made a significant contribution for manuscript finishing touches	made a significant contribution for manuscript finishing touches	-	-	NO
5672332	29163556	MY	2	designed the experiments, analyzed the data and wrote the manuscript|performed the main experiments|made a significant contribution for manuscript finishing touches	designed the experiments, analyzed the data and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5672332	29163556	MY	2	designed the experiments, analyzed the data and wrote the manuscript|performed the main experiments|made a significant contribution for manuscript finishing touches	performed the main experiments	Performed the experiments	Investigation	YES
5672332	29163556	MY	2	designed the experiments, analyzed the data and wrote the manuscript|performed the main experiments|made a significant contribution for manuscript finishing touches	made a significant contribution for manuscript finishing touches	-	-	NO
5672332	29163556	SC	2	contributed to the production and processing of the pictures	contributed to the production and processing of the pictures	-	Visualization	YES
5672332	29163556	TW	2	made a significant contribution for manuscript finishing touches	made a significant contribution for manuscript finishing touches	-	-	NO
5672332	29163556	WS	2	designed the experiments, analyzed the data and wrote the manuscript	designed the experiments, analyzed the data and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5672332	29163556	WY	2	designed the experiments, analyzed the data and wrote the manuscript	designed the experiments, analyzed the data and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5672332	29163556	YZ	2	performed the main experiments	performed the main experiments	Performed the experiments	Investigation	YES
5520325	28728593	J-LF	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5520325	28728593	YAK	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
1831498	17406679	JV	1	Designed research, performed research, analyzed data, and wrote the paper	Designed research, performed research, analyzed data, and wrote the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
1831498	17406679	LS	1	Designed research, performed research, analyzed data, and wrote the paper	Designed research, performed research, analyzed data, and wrote the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4572405	26413527	Yubao Lu	2	contributed equally to this work	contributed equally to this work	-	-	NO
4572405	26413527	Yushun Gong	2	contributed equally to this work	contributed equally to this work	-	-	NO
2212632	17988393	AS	2	participated in data collection and analysis	participated in data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
2212632	17988393	AW	2	participated in data collection and analysis	participated in data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
2212632	17988393	ER	2	participated in data collection and analysis	participated in data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
2212632	17988393	HH	2	participated in the study design and helped draft the manuscript while aiding in data collection	participated in the study design and helped draft the manuscript while aiding in data collection	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
2212632	17988393	JC	2	participated in the study design and helped draft the manuscript while aiding in data collection	participated in the study design and helped draft the manuscript while aiding in data collection	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
2212632	17988393	JM	2	participated in the study design and helped draft the manuscript while aiding in data collection	participated in the study design and helped draft the manuscript while aiding in data collection	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
2212632	17988393	JS	2	participated in the study design and helped draft the manuscript while aiding in data collection	participated in the study design and helped draft the manuscript while aiding in data collection	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
2212632	17988393	MK	2	participated in data collection and analysis	participated in data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
2212632	17988393	MR	2	participated in data collection and analysis	participated in data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
2212632	17988393	MT	2	participated in data collection and analysis	participated in data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
2212632	17988393	SJK	2	participated in data collection and analysis	participated in data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
2212632	17988393	ST	2	participated in the study design and helped draft the manuscript while aiding in data collection	participated in the study design and helped draft the manuscript while aiding in data collection	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
2212632	17988393	VD	2	participated in data collection and analysis	participated in data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
2212632	17988393	all authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4411139	25915903	IS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411139	25915903	IS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411139	25915903	IS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411139	25915903	IS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411139	25915903	IS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411139	25915903	JW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411139	25915903	JW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411139	25915903	JW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411139	25915903	JW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411139	25915903	JW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1831499	17406680	AD	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1831499	17406680	AD	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1831499	17406680	AD	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1831499	17406680	GM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Main author	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1831499	17406680	GM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Main author	Performed the experiments	Performed the experiments	Investigation	YES
1831499	17406680	GM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Main author	Analyzed the data	Analyzed the data	Formal analysis	YES
1831499	17406680	GM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Main author	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1831499	17406680	GM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Main author	Main author	Wrote the paper	Writing - Original Draft	YES
1831499	17406680	HJ	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1831499	17406680	HJ	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1831499	17406680	JK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1831499	17406680	JK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1831499	17406680	JW	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1831499	17406680	JW	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5672497	29163573	JY	PLoS52	designed the experiments|performed experiments|analyzed the data	designed the experiments	Conceived and designed the experiments	Methodology	YES
5672497	29163573	JY	PLoS52	designed the experiments|performed experiments|analyzed the data	performed experiments	Performed the experiments	Investigation	YES
5672497	29163573	JY	PLoS52	designed the experiments|performed experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5672497	29163573	PA	PLoS52	designed the experiments|analyzed the data|wrote the paper	designed the experiments	Conceived and designed the experiments	Methodology	YES
5672497	29163573	PA	PLoS52	designed the experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5672497	29163573	PA	PLoS52	designed the experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5672497	29163573	PB	PLoS52	designed the experiments|performed experiments|analyzed the data|wrote the paper	designed the experiments	Conceived and designed the experiments	Methodology	YES
5672497	29163573	PB	PLoS52	designed the experiments|performed experiments|analyzed the data|wrote the paper	performed experiments	Performed the experiments	Investigation	YES
5672497	29163573	PB	PLoS52	designed the experiments|performed experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5672497	29163573	PB	PLoS52	designed the experiments|performed experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5672497	29163573	ZW	PLoS52	designed the experiments|analyzed the data	designed the experiments	Conceived and designed the experiments	Methodology	YES
5672497	29163573	ZW	PLoS52	designed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
2214727	17997853	AH	2	made contribution to the acquisition and interpretation of data and revising the manuscript	made contribution to the acquisition and interpretation of data and revising the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Review & Editing	YES
2214727	17997853	AP	2	conceived the study, analysed the data, drafted and revised the manuscript	conceived the study, analysed the data, drafted and revised the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
2214727	17997853	DPN	2	made contributions to the interpretation of the data, drafted and revised the manuscript	made contributions to the interpretation of the data, drafted and revised the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft|Writing - Review & Editing	YES
2214727	17997853	JB	2	made contribution to the acquisition and interpretation of data and revising the manuscript	made contribution to the acquisition and interpretation of data and revising the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Review & Editing	YES
2214727	17997853	JM	2	made contribution to the drafting and revising the manuscript	made contribution to the drafting and revising the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5520361	28732469	AMC	2	helped with the discussion	helped with the discussion	-	-	NO
5520361	28732469	AMM	2	prepared genomic libraries, worked on genome assembly and detection of microsatellite sequences	prepared genomic libraries, worked on genome assembly and detection of microsatellite sequences	Performed the experiments	Investigation	YES
5520361	28732469	FGF	2	supervised the study and helped with the discussion	supervised the study and helped with the discussion	-	Supervision	YES
5520361	28732469	MEF	2	conceived the study, supervised the laboratory work, performed statistical analyses and drafted the manuscript	conceived the study, supervised the laboratory work, performed statistical analyses and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Supervision|Writing - Original Draft	YES
5520361	28732469	NTJ	2	helped to identify and collect all the accessions	helped to identify and collect all the accessions	Performed the experiments	Investigation	YES
5520361	28732469	SA	2	worked on dna extraction, primer design, multiplex panel development, marker genotyping, statistical analyses and drafted the manuscript	worked on dna extraction, primer design, multiplex panel development, marker genotyping, statistical analyses and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4411140	25915653	AB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411140	25915653	AB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411140	25915653	AB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411140	25915653	GW	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4411140	25915653	GW	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4411140	25915653	HK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411140	25915653	HK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411140	25915653	HK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411140	25915653	HK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411140	25915653	HK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411140	25915653	JS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411140	25915653	JS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411140	25915653	JS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411140	25915653	KK	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4411140	25915653	KK	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4411140	25915653	MS	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411140	25915653	MS	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411140	25915653	MZ	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411140	25915653	MZ	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411140	25915653	PR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411140	25915653	PR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411140	25915653	PR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411140	25915653	PR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411140	25915653	PT	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411140	25915653	PT	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411140	25915653	PT	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411140	25915653	SF	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411140	25915653	SF	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411140	25915653	WM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411140	25915653	WM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411140	25915653	WM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411140	25915653	WM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411140	25915653	WM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6189553	30275157	B.D.	2	contributed to the geochemistry and geodynamics sections and linked these to the overall tectonic framework	contributed to the geochemistry and geodynamics sections and linked these to the overall tectonic framework	-	-	NO
6189553	30275157	C.J.H.	2	were involved in the overall conception, design and writing of the manuscript	were involved in the overall conception, design and writing of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
6189553	30275157	F.A.C.	2	contributed to the geochemistry and geodynamics sections and linked these to the overall tectonic framework	contributed to the geochemistry and geodynamics sections and linked these to the overall tectonic framework	-	-	NO
6189553	30275157	O.N.	2	contributed to the geochemistry and geodynamics sections and linked these to the overall tectonic framework	contributed to the geochemistry and geodynamics sections and linked these to the overall tectonic framework	-	-	NO
6189553	30275157	P.A.C.	2	were involved in the overall conception, design and writing of the manuscript|wrote the section on palaeomagnetics	were involved in the overall conception, design and writing of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
6189553	30275157	P.A.C.	2	were involved in the overall conception, design and writing of the manuscript|wrote the section on palaeomagnetics	wrote the section on palaeomagnetics	Wrote the paper	Writing - Original Draft	YES
6189553	30275157	S.A.P.	2	wrote the section on palaeomagnetics	wrote the section on palaeomagnetics	Wrote the paper	Writing - Original Draft	YES
2217562	18045476	BC	7	specimen and statistical analysis	specimen and statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
2217562	18045476	CDW	7	data collection, statistical analysis	data collection, statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
2217562	18045476	CMK	7	manuscript preparation, data collection, specimen analysis	manuscript preparation, data collection, specimen analysis	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
2217562	18045476	CR	7	coordinator of testing facilities and assisted in data collection	coordinator of testing facilities and assisted in data collection	Performed the experiments	Investigation|Project administration	YES
2217562	18045476	DW	7	laboratory director of specimen analytical lab, obtained muscle sample, and directed specimen analysis	laboratory director of specimen analytical lab, obtained muscle sample, and directed specimen analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Supervision	YES
2217562	18045476	JJ	7	data collection and dietary analysis	data collection and dietary analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
2217562	18045476	LWT	7	specimen and statistical analysis	specimen and statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
2217562	18045476	MC	7	data collection and specimen analysis	data collection and specimen analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
2217562	18045476	MDR	7	primary author, oversaw all aspects of study including recruitment, data/specimen analysis, and manuscript preparation	primary author, oversaw all aspects of study including recruitment, data/specimen analysis, and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Supervision|Writing - Original Draft	YES
2217562	18045476	MG	7	secondary author	secondary author	-	-	NO
2217562	18045476	MI	7	study co-collaborator, statistical analysis, subject recruitment	study co-collaborator, statistical analysis, subject recruitment	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
2217562	18045476	RBK	7	principal investigator of the study who obtained grant funds for project, designed study, supervised data collection and analysis, supervised statistical analyses, and co-authored paper	principal investigator of the study who obtained grant funds for project, designed study, supervised data collection and analysis, supervised statistical analyses, and co-authored paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Funding acquisition|Investigation|Methodology|Supervision|Writing - Original Draft	YES
2217562	18045476	RW	7	served as medical director for study	served as medical director for study	-	-	NO
2217562	18045476	TH	7	data collection and specimen analysis	data collection and specimen analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
1832223	17406682	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1832223	17406682	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1832223	17406682	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1832223	17406682	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1832223	17406682	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1832223	17406682	CD	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1832223	17406682	CT	PLoS5	Proteo search engine for identification of proteins	Proteo search engine for identification of proteins	Performed the experiments	Investigation	YES
1832223	17406682	JB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1832223	17406682	JB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1832223	17406682	JB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1832223	17406682	JB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5672787	29163607	AE-M	5	made substantial contributions to the conception or design of the work (AF	made substantial contributions to the conception or design of the work (AF	Conceived and designed the experiments	Conceptualization	YES
5672787	29163607	AF	5	made substantial contributions to the conception or design of the work (AF	made substantial contributions to the conception or design of the work (AF	Conceived and designed the experiments	Conceptualization	YES
5672787	29163607	EM	5	made substantial contributions to the conception or design of the work (AF	made substantial contributions to the conception or design of the work (AF	Conceived and designed the experiments	Conceptualization	YES
5672787	29163607	HL	5	made substantial contributions to the conception or design of the work (AF	made substantial contributions to the conception or design of the work (AF	Conceived and designed the experiments	Conceptualization	YES
5672787	29163607	IC	5	made substantial contributions to the conception or design of the work (AF	made substantial contributions to the conception or design of the work (AF	Conceived and designed the experiments	Conceptualization	YES
5672787	29163607	JS	5	made substantial contributions to the conception or design of the work (AF	made substantial contributions to the conception or design of the work (AF	Conceived and designed the experiments	Conceptualization	YES
5672787	29163607	MB	5	made substantial contributions to the conception or design of the work (AF	made substantial contributions to the conception or design of the work (AF	Conceived and designed the experiments	Conceptualization	YES
5672787	29163607	WQ	5	made substantial contributions to the conception or design of the work (AF	made substantial contributions to the conception or design of the work (AF	Conceived and designed the experiments	Conceptualization	YES
4411141	25915864	AT	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4411141	25915864	HY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411141	25915864	HY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411141	25915864	HY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411141	25915864	HY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411141	25915864	KT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411141	25915864	KT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411141	25915864	KT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411141	25915864	KT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411141	25915864	MK	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4411141	25915864	MK	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4411141	25915864	NS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4411141	25915864	NS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4411141	25915864	RT	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4411141	25915864	RT	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4411141	25915864	SK	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4411141	25915864	SK	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4411141	25915864	ST	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411141	25915864	SY	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4411141	25915864	SY	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4411141	25915864	TS	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411141	25915864	YN	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
3699431	23800294	AK	PLoS52	commented and supervised on the manuscript	commented and supervised on the manuscript	-	Supervision	YES
3699431	23800294	CO	PLoS52	commented and supervised on the manuscript	commented and supervised on the manuscript	-	Supervision	YES
3699431	23800294	RY	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3699431	23800294	YN	PLoS52	wrote the paper|designed and performed the experiments	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3699431	23800294	YN	PLoS52	wrote the paper|designed and performed the experiments	designed and performed the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6189554	30275165	All	2	contributors who do not meet all of these criteria should be included in the acknowledgements	contributors who do not meet all of these criteria should be included in the acknowledgements	-	-	NO
6189554	30275165	All authors	2	read, contributed to and approved the manuscript	read, contributed to and approved the manuscript	-	-	NO
6189554	30275165	F.A.C.	2	designed the study|drafted the figures	designed the study	Conceived and designed the experiments	Methodology	YES
6189554	30275165	F.A.C.	2	designed the study|drafted the figures	drafted the figures	Wrote the paper	Visualization|Writing - Original Draft	YES
6189554	30275165	O.N.	2	designed the study|drafted the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
6189554	30275165	O.N.	2	designed the study|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
6189554	30275165	P.A.C.	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
6189554	30275165	R.F.W.	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
6189554	30275165	Y.N.J.	2	drafted the figures	drafted the figures	Wrote the paper	Visualization|Writing - Original Draft	YES
4572435	26421276	Takeshi Yokoo	2	contributed equally to the editorial	contributed equally to the editorial	-	-	NO
4572435	26421276	Trevor Andrews	2	contributed equally to the editorial	contributed equally to the editorial	-	-	NO
1832224	17426809	AV	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1832224	17426809	AV	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1832224	17426809	FK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1832224	17426809	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Collected specimens	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1832224	17426809	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Collected specimens	Performed the experiments	Performed the experiments	Investigation	YES
1832224	17426809	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Collected specimens	Analyzed the data	Analyzed the data	Formal analysis	YES
1832224	17426809	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Collected specimens	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1832224	17426809	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Collected specimens	Collected specimens	Performed the experiments	Investigation	YES
1832224	17426809	TH	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5521070	28732463	BS	2	conceived the project	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5521070	28732463	MB	2	performed mass spectrometry experiments and analysis	performed mass spectrometry experiments and analysis	Performed the experiments	Investigation	YES
5521070	28732463	MC	2	performed mass spectrometry experiments and analysis	performed mass spectrometry experiments and analysis	Performed the experiments	Investigation	YES
5521070	28732463	ODA	2	wrote the web interface for sharing the predictions and other data	wrote the web interface for sharing the predictions and other data	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Software|Writing - Original Draft	YES
5521070	28732463	RF	2	conceived the project|performed all computational analysis and wrote the manuscript	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5521070	28732463	RF	2	conceived the project|performed all computational analysis and wrote the manuscript	performed all computational analysis and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5521070	28732463	SK	2	performed mass spectrometry experiments and analysis	performed mass spectrometry experiments and analysis	Performed the experiments	Investigation	YES
5521070	28732463	SM	2	performed mass spectrometry experiments and analysis	performed mass spectrometry experiments and analysis	Performed the experiments	Investigation	YES
4936982	27388754	EA	2	conceived the study and participated in its design	conceived the study and participated in its design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4936982	27388754	HSA	2	coordinated and collected all the underlying information related to the pet studies included	coordinated and collected all the underlying information related to the pet studies included	Performed the experiments	Investigation|Project administration	YES
4936982	27388754	HW	2	conceived the study and participated in its design	conceived the study and participated in its design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4936982	27388754	JG	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4936982	27388754	SL	2	conceived the study and participated in its design	conceived the study and participated in its design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4936982	27388754	SS	2	conceived the study and participated in its design|drafted the manuscript	conceived the study and participated in its design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4936982	27388754	SS	2	conceived the study and participated in its design|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4936982	27388754	SSE	2	conceived the study and participated in its design|drafted the manuscript	conceived the study and participated in its design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4936982	27388754	SSE	2	conceived the study and participated in its design|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
2217563	18053194	All authors	2	participated in the design of the study	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
2217563	18053194	FA	2	collected data	collected data	Performed the experiments	Investigation	YES
2217563	18053194	HH	2	collected data|drafted the manuscript	collected data	Performed the experiments	Investigation	YES
2217563	18053194	HH	2	collected data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
2217563	18053194	JB	2	validated the ball flight test method	validated the ball flight test method	Performed the experiments	Validation	YES
2217563	18053194	LS	2	collected data	collected data	Performed the experiments	Investigation	YES
2217563	18053194	MW	2	collected data	collected data	Performed the experiments	Investigation	YES
5673645	29163619	H-LH	2	designed the experiments|did data analyses|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5673645	29163619	H-LH	2	designed the experiments|did data analyses|wrote the manuscript	did data analyses	Analyzed the data	Formal analysis	YES
5673645	29163619	H-LH	2	designed the experiments|did data analyses|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5673645	29163619	H-WJ	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5673645	29163619	SS	2	designed the experiments|performed experiments|did data analyses|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5673645	29163619	SS	2	designed the experiments|performed experiments|did data analyses|wrote the manuscript	performed experiments	Performed the experiments	Investigation	YES
5673645	29163619	SS	2	designed the experiments|performed experiments|did data analyses|wrote the manuscript	did data analyses	Analyzed the data	Formal analysis	YES
5673645	29163619	SS	2	designed the experiments|performed experiments|did data analyses|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4411142	25915909	AB	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411142	25915909	AB	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411142	25915909	AD	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411142	25915909	AD	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411142	25915909	AG	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411142	25915909	DM	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411142	25915909	MF	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411142	25915909	MF	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2221871	18053263	B. Scott	2	conceived and designed the study, performed statistical analysis and wrote the final manuscript	conceived and designed the study, performed statistical analysis and wrote the final manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
2221871	18053263	J. Fernandes	2	conceived and designed the study and collected all data	conceived and designed the study and collected all data	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
2221871	18053263	M. Lehman	2	conceived and designed the study and collected all data	conceived and designed the study and collected all data	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
1832225	17406676	DG	PLoS5	Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1832225	17406676	DG	PLoS5	Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1832225	17406676	MF	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5521101	28732465	GHP	2	participated in the design of the study, carried out the analyses and results interpretation, were involved in the discussions, prepared and drafted the manuscript	participated in the design of the study, carried out the analyses and results interpretation, were involved in the discussions, prepared and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5521101	28732465	KMK	2	participated in the design of the study, carried out the analyses and results interpretation, were involved in the discussions, prepared and drafted the manuscript	participated in the design of the study, carried out the analyses and results interpretation, were involved in the discussions, prepared and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4938836	27393423	BT	2	designed the experiment, conducted the operation personally and drafted the manuscript	designed the experiment, conducted the operation personally and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
4938836	27393423	DLL	2	did a lot of work in the imaging examination and data analysis	did a lot of work in the imaging examination and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
4938836	27393423	HKG	2	designed the experiment, conducted the operation personally and drafted the manuscript	designed the experiment, conducted the operation personally and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
4938836	27393423	MI	2	model and revising the manuscript critically for important intellectual content	model and revising the manuscript critically for important intellectual content	Performed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
4938836	27393423	SM	2	did assisted work in these process	did assisted work in these process	-	-	NO
4938836	27393423	WB	2	did a lot of work in the imaging examination and data analysis	did a lot of work in the imaging examination and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
4938836	27393423	YBW	2	did assisted work in these process	did assisted work in these process	-	-	NO
4938836	27393423	ZHL	2	did assisted work in these process	did assisted work in these process	-	-	NO
1838519	17426816	BF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1838519	17426816	BF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1838519	17426816	BF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1838519	17426816	BF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1838519	17426816	EM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1838519	17426816	EM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1838519	17426816	EM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1838519	17426816	RT	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411143	25915771	CG	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4411143	25915771	CG	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4411143	25915771	CP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411143	25915771	CP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4411143	25915771	CP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411143	25915771	EP	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4411143	25915771	EP	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4411143	25915771	HMV	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4411143	25915771	HMV	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411143	25915771	LV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411143	25915771	LV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411143	25915771	LV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411143	25915771	LV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411143	25915771	LV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411143	25915771	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411143	25915771	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411143	25915771	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411143	25915771	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411143	25915771	NJPO	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4411143	25915771	NJPO	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2221872	18067677	CDW	2	assisted in the data acquisition	assisted in the data acquisition	Performed the experiments	Investigation	YES
2221872	18067677	DSW	2	conceived the study, developed the study design, secured the funding for the project, assisted and provided oversight for all data acquisition and statistical analysis, assisted in drafting the manuscript, and served as the faculty mentor for the project	conceived the study, developed the study design, secured the funding for the project, assisted and provided oversight for all data acquisition and statistical analysis, assisted in drafting the manuscript, and served as the faculty mentor for the project	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Funding acquisition|Investigation|Methodology|Resources|Supervision|Writing - Original Draft	YES
2221872	18067677	JAW	2	assisted in the data acquisition	assisted in the data acquisition	Performed the experiments	Investigation	YES
2221872	18067677	LWT	2	assisted in the data acquisition	assisted in the data acquisition	Performed the experiments	Investigation	YES
2221872	18067677	MDR	2	assisted in data acquisition, statistical analysis, and writing of the manuscript	assisted in data acquisition, statistical analysis, and writing of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
2221872	18067677	RBK	2	assisted with oversight, lab personnel, and in the statistical analysis	assisted with oversight, lab personnel, and in the statistical analysis	Analyzed the data	Formal analysis|Supervision	YES
3920604	24587805	Antonio Filippini	2	equally contributed to this work	equally contributed to this work	-	-	NO
3920604	24587805	Elio Ziparo	2	equally contributed to this work	equally contributed to this work	-	-	NO
5673649	29163615	MB	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5673649	29163615	MB	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5673649	29163615	NT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5673649	29163615	NT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5673649	29163615	NT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1838520	17426817	DW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1838520	17426817	DW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1838520	17426817	DW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1838520	17426817	DW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1838520	17426817	EB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1838520	17426817	EB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1838520	17426817	EB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6232575	30373944	All authors	2	analysed the comparison results|gave final approval for publication	analysed the comparison results	Analyzed the data	Formal analysis	YES
6232575	30373944	All authors	2	analysed the comparison results|gave final approval for publication	gave final approval for publication	-	-	NO
6232575	30373944	C.S.	2	conceived and performed the validation measurements	conceived and performed the validation measurements	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Validation	YES
6232575	30373944	D.W.P.T.	2	conceived and performed the validation measurements	conceived and performed the validation measurements	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Validation	YES
6232575	30373944	G.G.	2	conceived and drafted the manuscript|developed the wigner function theory	conceived and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
6232575	30373944	G.G.	2	conceived and drafted the manuscript|developed the wigner function theory	developed the wigner function theory	-	-	NO
6232575	30373944	G.T.	2	developed the wigner function theory	developed the wigner function theory	-	-	NO
6232575	30373944	J.R.	2	conceived and drafted the manuscript|developed the method of moments theory	conceived and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
6232575	30373944	J.R.	2	conceived and drafted the manuscript|developed the method of moments theory	developed the method of moments theory	Performed the experiments	Methodology	YES
6232575	30373944	M.H.	2	did the numerical work and compared with the experimental data	did the numerical work and compared with the experimental data	Performed the experiments	Formal analysis|Investigation	YES
6232575	30373944	M.H.B.	2	conceived and performed the validation measurements|did the numerical work and compared with the experimental data	conceived and performed the validation measurements	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Validation	YES
6232575	30373944	M.H.B.	2	conceived and performed the validation measurements|did the numerical work and compared with the experimental data	did the numerical work and compared with the experimental data	Performed the experiments	Formal analysis|Investigation	YES
6232575	30373944	P.R.	2	developed the method of moments theory	developed the method of moments theory	Performed the experiments	Methodology	YES
6232575	30373944	S.C.C.	2	developed the wigner function theory	developed the wigner function theory	-	-	NO
5673651	29163616	AK	PLoS52	assisted in molecular analysis	assisted in molecular analysis	Performed the experiments	Investigation	YES
5673651	29163616	LS	PLoS52	conceived and designed the experiments|contributed to the writing of the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5673651	29163616	LS	PLoS52	conceived and designed the experiments|contributed to the writing of the manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5673651	29163616	RS	PLoS52	assisted in molecular analysis	assisted in molecular analysis	Performed the experiments	Investigation	YES
5673651	29163616	SK	PLoS52	produced the transgenics and performed molecular analysis|performed physiological and biochemical experiments of transgenic plants	produced the transgenics and performed molecular analysis	Performed the experiments	Investigation	YES
5673651	29163616	SK	PLoS52	produced the transgenics and performed molecular analysis|performed physiological and biochemical experiments of transgenic plants	performed physiological and biochemical experiments of transgenic plants	Performed the experiments	Investigation	YES
2235827	18173851	HB	2	participated in the development of the original idea, research design, data interpretation and manuscript preparation	participated in the development of the original idea, research design, data interpretation and manuscript preparation	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
2235827	18173851	JD	2	participated in research design, data interpretation and manuscript preparation	participated in research design, data interpretation and manuscript preparation	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
2235827	18173851	JL	2	participated in subject screening, interviews and follow-up, analysis of all diet records and medical reports, and manuscript preparation	participated in subject screening, interviews and follow-up, analysis of all diet records and medical reports, and manuscript preparation	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
2235827	18173851	KG	2	conceived the idea, participated in research design, subject interviews and follow-up, data collection and analysis, and manuscript preparation	conceived the idea, participated in research design, subject interviews and follow-up, data collection and analysis, and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
2235827	18173851	PH	2	participated in research design, collection and analysis of diet records, and statistical analysis and interpretation of data	participated in research design, collection and analysis of diet records, and statistical analysis and interpretation of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5521155	28732532	GATE	2	to real data	to real data	-	-	NO
5521155	28732532	QL	2	designed the study|prepared the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5521155	28732532	QL	2	designed the study|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5521155	28732532	WZ	2	designed the study|performed the simulation analyses|prepared the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5521155	28732532	WZ	2	designed the study|performed the simulation analyses|prepared the manuscript	performed the simulation analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5521155	28732532	WZ	2	designed the study|performed the simulation analyses|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5521155	28732532	YL	2	designed the study|performed the simulation analyses|prepared the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5521155	28732532	YL	2	designed the study|performed the simulation analyses|prepared the manuscript	performed the simulation analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5521155	28732532	YL	2	designed the study|performed the simulation analyses|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
4963336	27464623	All authors	2	participated in the drafting and editing of the manuscript	participated in the drafting and editing of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4963336	27464623	JR	2	directed the patient acquisitions, performed the visual and quantitative analysis, and created the study design	directed the patient acquisitions, performed the visual and quantitative analysis, and created the study design	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Investigation|Methodology|Supervision|Visualization	YES
4963336	27464623	JS	2	processed the acquired data and lead the statistical analysis of results	processed the acquired data and lead the statistical analysis of results	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
4963336	27464623	MB	2	directed the patient acquisitions, performed the visual and quantitative analysis, and created the study design	directed the patient acquisitions, performed the visual and quantitative analysis, and created the study design	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Investigation|Methodology|Supervision|Visualization	YES
4963336	27464623	PR	2	processed the acquired data and lead the statistical analysis of results	processed the acquired data and lead the statistical analysis of results	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
4963336	27464623	TK	2	directed the patient acquisitions, performed the visual and quantitative analysis, and created the study design	directed the patient acquisitions, performed the visual and quantitative analysis, and created the study design	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Investigation|Methodology|Supervision|Visualization	YES
4411144	25915760	HO	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411144	25915760	KN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411144	25915760	KN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411144	25915760	KN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411144	25915760	KN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411144	25915760	KN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411144	25915760	MK	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4411144	25915760	MK	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411144	25915760	MZ	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411144	25915760	SN	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411144	25915760	SU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411144	25915760	SU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411144	25915760	SU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411144	25915760	SU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411144	25915760	TO	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1838521	17426810	AF	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1838521	17426810	AF	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1838521	17426810	AP	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1838521	17426810	AP	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1838521	17426810	CD	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1838521	17426810	CD	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1838521	17426810	CD	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1838521	17426810	CN	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1838521	17426810	CN	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1838521	17426810	DK	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1838521	17426810	DK	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1838521	17426810	HG	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1838521	17426810	HG	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1838521	17426810	KR	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1838521	17426810	KR	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1838521	17426810	KR	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1838521	17426810	SA	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1838521	17426810	SC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1838521	17426810	SC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1838521	17426810	SC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1838521	17426810	SC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4573221	26421278	Fei Li	2	designed the structure and interface of the software and drafted the paper	designed the structure and interface of the software and drafted the paper	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Software|Writing - Original Draft	YES
4573221	26421278	Xiaochen Bo	2	participated in the design of the package and helped to draft the paper	participated in the design of the package and helped to draft the paper	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
4573221	26421278	Xiaofei Zheng	2	participated in the design of the package and helped to draft the paper	participated in the design of the package and helped to draft the paper	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
4573221	26421278	Yang Cao	2	implemented the package and wrote the user manual	implemented the package and wrote the user manual	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
2244642	18039377	All authors	2	contributed equally to this work	contributed equally to this work	-	-	NO
5522595	28732460	All authors	2	drafted and approved the final manuscript	drafted and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5522595	28732460	BMC	2	selected snps and designed the goldengate chip	selected snps and designed the goldengate chip	Conceived and designed the experiments	-	YES
5522595	28732460	BV	2	provided valuable input in data analyses and interpretation, and critically reviewed the manuscript	provided valuable input in data analyses and interpretation, and critically reviewed the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
5522595	28732460	DKR	2	analysed data and drafted the manuscript	analysed data and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5522595	28732460	FC	2	discovered the snps	discovered the snps	-	-	NO
5522595	28732460	JAG	2	conceived, designed and supervised the study, contributed to the interpretation of the data and to the writing of the manuscript	conceived, designed and supervised the study, contributed to the interpretation of the data and to the writing of the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Methodology|Resources|Supervision|Writing - Original Draft	YES
5522595	28732460	JF	2	provided valuable input in data analyses and interpretation, and critically reviewed the manuscript	provided valuable input in data analyses and interpretation, and critically reviewed the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
5522595	28732460	LS	2	processed samples and analysed data	processed samples and analysed data	Analyzed the data	Data curation|Formal analysis	YES
5522595	28732460	MLP	2	helped with pedigree refinement	helped with pedigree refinement	-	-	NO
4411145	25915902	CSE	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411145	25915902	DDX	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411145	25915902	HTY	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4411145	25915902	HY	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4411145	25915902	JDC	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411145	25915902	JDC	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411145	25915902	JTC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4411145	25915902	JTC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411145	25915902	JUME	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411145	25915902	LYY	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411145	25915902	ML	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411145	25915902	ML	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411145	25915902	MMOO	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411145	25915902	RAM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411145	25915902	SMN	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411145	25915902	XFZ	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4411145	25915902	XFZ	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1838522	17415407	JM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1838522	17415407	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1838522	17415407	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1838522	17415407	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1838522	17415407	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1838522	17415407	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1838522	17415407	MS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1838522	17415407	RW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1838522	17415407	RW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1838522	17415407	RW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1838522	17415407	RW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1838522	17415407	RW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5673658	29163610	CM	PLoS52	carried out the experiments|wrote the paper	carried out the experiments	Performed the experiments	Investigation	YES
5673658	29163610	CM	PLoS52	carried out the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5673658	29163610	JC	PLoS52	carried out the experiments|wrote the paper	carried out the experiments	Performed the experiments	Investigation	YES
5673658	29163610	JC	PLoS52	carried out the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5673658	29163610	SS	PLoS52	designed the experiment|carried out the experiments|wrote the paper	designed the experiment	Conceived and designed the experiments	Methodology	YES
5673658	29163610	SS	PLoS52	designed the experiment|carried out the experiments|wrote the paper	carried out the experiments	Performed the experiments	Investigation	YES
5673658	29163610	SS	PLoS52	designed the experiment|carried out the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5673658	29163610	The authors	PLoS52	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	Performed the experiments	Investigation	YES
5673658	29163610	YT	PLoS52	designed the experiment|wrote the paper	designed the experiment	Conceived and designed the experiments	Methodology	YES
5673658	29163610	YT	PLoS52	designed the experiment|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4967051	27473846	ADS	2	was responsible for the pet-ct study design and the data evaluation, coordinated the project and contributed to the manuscript	was responsible for the pet-ct study design and the data evaluation, coordinated the project and contributed to the manuscript	Conceived and designed the experiments	Methodology|Project administration	YES
4967051	27473846	AP	2	participated in the design of the study, coordinated the work and contributed to draft the manuscript	participated in the design of the study, coordinated the work and contributed to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft	YES
4967051	27473846	CS	2	performed the pet-ct studies	performed the pet-ct studies	Performed the experiments	Investigation	YES
4967051	27473846	CT	2	data and drafted the manuscript	data and drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4967051	27473846	JH	2	was responsible for the selection of the patients who received the ipilimumab therapy	was responsible for the selection of the patients who received the ipilimumab therapy	-	-	NO
4967051	27473846	LP	2	was responsible for the post processing of the pet-ct data	was responsible for the post processing of the pet-ct data	Analyzed the data	Data curation	YES
4967051	27473846	TT	2	participated in the design of the study and the draft of the manuscript	participated in the design of the study and the draft of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4573223	26421280	All authors	2	participated in editing	participated in editing	Wrote the paper	Writing - Review & Editing	YES
4573223	26421280	Jun Li	2	designed research, analyzed the data, and wrote the paper	designed research, analyzed the data, and wrote the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
2253504	18230170	EDR	2	played an important role in data collection and manuscript preparation	played an important role in data collection and manuscript preparation	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
2253504	18230170	JRS	2	played an important role in study design and manuscript preparation	played an important role in study design and manuscript preparation	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
2253504	18230170	JTC	2	was the senior author and played an important role in study design, data collection, data analysis and interpretation, and manuscript preparation	was the senior author and played an important role in study design, data collection, data analysis and interpretation, and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
2253504	18230170	TJH	2	was the primary author of the manuscript	was the primary author of the manuscript	Wrote the paper	Writing - Original Draft	YES
6232598	30420541	All authors	2	gave final approval for publication	gave final approval for publication	-	-	NO
6232598	30420541	H.M.	2	carried out the field survey and ethological experiments and participated in data analysis	carried out the field survey and ethological experiments and participated in data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6232598	30420541	T.T.	2	carried out the field survey and ethological experiments and participated in data analysis	carried out the field survey and ethological experiments and participated in data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6232598	30420541	V.B.	2	coordinated the study and helped write the manuscript	coordinated the study and helped write the manuscript	Wrote the paper	Project administration|Writing - Original Draft	YES
6232598	30420541	Y.-P.G.	2	carried out the field survey and ethological experiments and participated in data analysis|wrote the manuscript and designed the experiment	carried out the field survey and ethological experiments and participated in data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6232598	30420541	Y.-P.G.	2	carried out the field survey and ethological experiments and participated in data analysis|wrote the manuscript and designed the experiment	wrote the manuscript and designed the experiment	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3928863	24627685	Costanza Montagna	2	equally contributed to this work	equally contributed to this work	-	-	NO
3928863	24627685	Salvatore Rizza	2	equally contributed to this work	equally contributed to this work	-	-	NO
2263015	18186936	AP	2	sought out the data source, performed data analysis and drafted the manuscript	sought out the data source, performed data analysis and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
2263015	18186936	DPN	2	assisted with data interpretation and contributed to the manuscript	assisted with data interpretation and contributed to the manuscript	Analyzed the data	Formal analysis	YES
1838523	17426813	AD	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1838523	17426813	AD	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1838523	17426813	IC	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1838523	17426813	IC	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1838523	17426813	JP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1838523	17426813	JP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1838523	17426813	JP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1838523	17426813	JP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1838523	17426813	LA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1838523	17426813	LA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1838523	17426813	LA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1838523	17426813	LA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1838523	17426813	LR	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1838523	17426813	LR	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1838523	17426813	MD	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1838523	17426813	MD	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1838523	17426813	MM	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1838523	17426813	MM	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1838523	17426813	MV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1838523	17426813	MV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1838523	17426813	MV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1838523	17426813	MV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1838523	17426813	MV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4573224	26421277	Qi Tang	2	contributed equally	contributed equally	-	-	NO
4573224	26421277	Yi Song	2	contributed equally	contributed equally	-	-	NO
5674934	29163576	HM	2	performed the research and analyzed the data	performed the research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5674934	29163576	KS	2	performed the research and analyzed the data	performed the research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5674934	29163576	MP	2	designed the research, performed research, analyzed the data, and wrote the article	designed the research, performed research, analyzed the data, and wrote the article	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5674934	29163576	MS	2	performed the research and analyzed the data	performed the research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5674934	29163576	SN	2	designed the research, performed research, analyzed the data, and wrote the article	designed the research, performed research, analyzed the data, and wrote the article	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5674934	29163576	TK	2	designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
552303	15720717	CU	2	conceived of, and supervised the study, and edited the manuscript	conceived of, and supervised the study, and edited the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Supervision|Writing - Review & Editing	YES
552303	15720717	MD	2	performed all analyses and wrote the manuscript	performed all analyses and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4411147	25915506	AH	PLoS5	Performed the experiments|Gave final approval of the version to be published|Agreed to be accountable for all aspects of the work	Performed the experiments	Performed the experiments	Investigation	YES
4411147	25915506	AH	PLoS5	Performed the experiments|Gave final approval of the version to be published|Agreed to be accountable for all aspects of the work	Gave final approval of the version to be published	-	-	NO
4411147	25915506	AH	PLoS5	Performed the experiments|Gave final approval of the version to be published|Agreed to be accountable for all aspects of the work	Agreed to be accountable for all aspects of the work	-	-	NO
4411147	25915506	GMP	PLoS5	Analyzed the data|Wrote the paper|Drafted the article or revised it critically for important intellectual content|Gave final approval of the version to be published|Agreed to be accountable for all aspects of the work	Analyzed the data	Analyzed the data	Formal analysis	YES
4411147	25915506	GMP	PLoS5	Analyzed the data|Wrote the paper|Drafted the article or revised it critically for important intellectual content|Gave final approval of the version to be published|Agreed to be accountable for all aspects of the work	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411147	25915506	GMP	PLoS5	Analyzed the data|Wrote the paper|Drafted the article or revised it critically for important intellectual content|Gave final approval of the version to be published|Agreed to be accountable for all aspects of the work	Drafted the article or revised it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4411147	25915506	GMP	PLoS5	Analyzed the data|Wrote the paper|Drafted the article or revised it critically for important intellectual content|Gave final approval of the version to be published|Agreed to be accountable for all aspects of the work	Gave final approval of the version to be published	-	-	NO
4411147	25915506	GMP	PLoS5	Analyzed the data|Wrote the paper|Drafted the article or revised it critically for important intellectual content|Gave final approval of the version to be published|Agreed to be accountable for all aspects of the work	Agreed to be accountable for all aspects of the work	-	-	NO
4411147	25915506	ICM	PLoS5	Conceived and designed the experiments|Gave final approval of the version to be published|Agreed to be accountable for all aspects of the work	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411147	25915506	ICM	PLoS5	Conceived and designed the experiments|Gave final approval of the version to be published|Agreed to be accountable for all aspects of the work	Gave final approval of the version to be published	-	-	NO
4411147	25915506	ICM	PLoS5	Conceived and designed the experiments|Gave final approval of the version to be published|Agreed to be accountable for all aspects of the work	Agreed to be accountable for all aspects of the work	-	-	NO
4411147	25915506	JHM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Drafted the article or revised it critically for important intellectual content|Gave final approval of the version to be published|Agreed to be accountable for all aspects of the work	Performed the experiments	Performed the experiments	Investigation	YES
4411147	25915506	JHM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Drafted the article or revised it critically for important intellectual content|Gave final approval of the version to be published|Agreed to be accountable for all aspects of the work	Analyzed the data	Analyzed the data	Formal analysis	YES
4411147	25915506	JHM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Drafted the article or revised it critically for important intellectual content|Gave final approval of the version to be published|Agreed to be accountable for all aspects of the work	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411147	25915506	JHM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Drafted the article or revised it critically for important intellectual content|Gave final approval of the version to be published|Agreed to be accountable for all aspects of the work	Drafted the article or revised it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4411147	25915506	JHM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Drafted the article or revised it critically for important intellectual content|Gave final approval of the version to be published|Agreed to be accountable for all aspects of the work	Gave final approval of the version to be published	-	-	NO
4411147	25915506	JHM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Drafted the article or revised it critically for important intellectual content|Gave final approval of the version to be published|Agreed to be accountable for all aspects of the work	Agreed to be accountable for all aspects of the work	-	-	NO
4411147	25915506	KC	PLoS5	Performed the experiments|Analyzed the data|Drafted the article or revised it critically for important intellectual content|Gave final approval of the version to be published|Agreed to be accountable for all aspects of the work	Performed the experiments	Performed the experiments	Investigation	YES
4411147	25915506	KC	PLoS5	Performed the experiments|Analyzed the data|Drafted the article or revised it critically for important intellectual content|Gave final approval of the version to be published|Agreed to be accountable for all aspects of the work	Analyzed the data	Analyzed the data	Formal analysis	YES
4411147	25915506	KC	PLoS5	Performed the experiments|Analyzed the data|Drafted the article or revised it critically for important intellectual content|Gave final approval of the version to be published|Agreed to be accountable for all aspects of the work	Drafted the article or revised it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4411147	25915506	KC	PLoS5	Performed the experiments|Analyzed the data|Drafted the article or revised it critically for important intellectual content|Gave final approval of the version to be published|Agreed to be accountable for all aspects of the work	Gave final approval of the version to be published	-	-	NO
4411147	25915506	KC	PLoS5	Performed the experiments|Analyzed the data|Drafted the article or revised it critically for important intellectual content|Gave final approval of the version to be published|Agreed to be accountable for all aspects of the work	Agreed to be accountable for all aspects of the work	-	-	NO
4411147	25915506	RG	PLoS5	Performed the experiments|Drafted the article or revised it critically for important intellectual content|Gave final approval of the version to be published|Agreed to be accountable for all aspects of the work	Performed the experiments	Performed the experiments	Investigation	YES
4411147	25915506	RG	PLoS5	Performed the experiments|Drafted the article or revised it critically for important intellectual content|Gave final approval of the version to be published|Agreed to be accountable for all aspects of the work	Drafted the article or revised it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4411147	25915506	RG	PLoS5	Performed the experiments|Drafted the article or revised it critically for important intellectual content|Gave final approval of the version to be published|Agreed to be accountable for all aspects of the work	Gave final approval of the version to be published	-	-	NO
4411147	25915506	RG	PLoS5	Performed the experiments|Drafted the article or revised it critically for important intellectual content|Gave final approval of the version to be published|Agreed to be accountable for all aspects of the work	Agreed to be accountable for all aspects of the work	-	-	NO
4411147	25915506	RR	PLoS5	Contributed reagents/materials/analysis tools|Gave final approval of the version to be published|Agreed to be accountable for all aspects of the work	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411147	25915506	RR	PLoS5	Contributed reagents/materials/analysis tools|Gave final approval of the version to be published|Agreed to be accountable for all aspects of the work	Gave final approval of the version to be published	-	-	NO
4411147	25915506	RR	PLoS5	Contributed reagents/materials/analysis tools|Gave final approval of the version to be published|Agreed to be accountable for all aspects of the work	Agreed to be accountable for all aspects of the work	-	-	NO
4411147	25915506	TK	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Gave final approval of the version to be published|Agreed to be accountable for all aspects of the work	Performed the experiments	Performed the experiments	Investigation	YES
4411147	25915506	TK	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Gave final approval of the version to be published|Agreed to be accountable for all aspects of the work	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411147	25915506	TK	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Gave final approval of the version to be published|Agreed to be accountable for all aspects of the work	Gave final approval of the version to be published	-	-	NO
4411147	25915506	TK	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Gave final approval of the version to be published|Agreed to be accountable for all aspects of the work	Agreed to be accountable for all aspects of the work	-	-	NO
4411147	25915506	VP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Drafted the article or revised it critically for important intellectual content|Gave final approval of the version to be published|Agreed to be accountable for all aspects of the work	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411147	25915506	VP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Drafted the article or revised it critically for important intellectual content|Gave final approval of the version to be published|Agreed to be accountable for all aspects of the work	Performed the experiments	Performed the experiments	Investigation	YES
4411147	25915506	VP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Drafted the article or revised it critically for important intellectual content|Gave final approval of the version to be published|Agreed to be accountable for all aspects of the work	Analyzed the data	Analyzed the data	Formal analysis	YES
4411147	25915506	VP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Drafted the article or revised it critically for important intellectual content|Gave final approval of the version to be published|Agreed to be accountable for all aspects of the work	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411147	25915506	VP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Drafted the article or revised it critically for important intellectual content|Gave final approval of the version to be published|Agreed to be accountable for all aspects of the work	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411147	25915506	VP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Drafted the article or revised it critically for important intellectual content|Gave final approval of the version to be published|Agreed to be accountable for all aspects of the work	Drafted the article or revised it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4411147	25915506	VP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Drafted the article or revised it critically for important intellectual content|Gave final approval of the version to be published|Agreed to be accountable for all aspects of the work	Gave final approval of the version to be published	-	-	NO
4411147	25915506	VP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Drafted the article or revised it critically for important intellectual content|Gave final approval of the version to be published|Agreed to be accountable for all aspects of the work	Agreed to be accountable for all aspects of the work	-	-	NO
4411147	25915506	WW	PLoS5	Performed the experiments|Gave final approval of the version to be published|Agreed to be accountable for all aspects of the work	Performed the experiments	Performed the experiments	Investigation	YES
4411147	25915506	WW	PLoS5	Performed the experiments|Gave final approval of the version to be published|Agreed to be accountable for all aspects of the work	Gave final approval of the version to be published	-	-	NO
4411147	25915506	WW	PLoS5	Performed the experiments|Gave final approval of the version to be published|Agreed to be accountable for all aspects of the work	Agreed to be accountable for all aspects of the work	-	-	NO
6282402	30478202	All the authors	2	discussed the results, wrote the manuscript and approved the final manuscript	discussed the results, wrote the manuscript and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6282402	30478202	R.I.	2	conceived of this study and performed simulations	conceived of this study and performed simulations	Conceived and designed the experiments|Performed the experiments	Conceptualization|Formal analysis|Investigation	YES
3751045	23924507	ARMA	2	participated in cloning of the genes and enzyme assay optimization, prepared the manuscript, and supervised experimental design	participated in cloning of the genes and enzyme assay optimization, prepared the manuscript, and supervised experimental design	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Supervision|Writing - Original Draft	YES
3751045	23924507	BJ	2	participated in cloning of the genes, carried out heterolgous expression and purification of the enzymes, participated in enzyme assay optimization, generated and characterized recombinant strains, and helped to draft the manuscript	participated in cloning of the genes, carried out heterolgous expression and purification of the enzymes, participated in enzyme assay optimization, generated and characterized recombinant strains, and helped to draft the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3751045	23924507	RLM	2	drafted the concept of the study and participated in the drawing of the phylogenetic tree	drafted the concept of the study and participated in the drawing of the phylogenetic tree	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
5674935	29163603	AP-S	7	bioinformatics and wrote the article	bioinformatics and wrote the article	Wrote the paper	Formal analysis|Writing - Original Draft	YES
5674935	29163603	EC	7	Experiment design and original set of experiments that led to the research, article writing, and revisions	Experiment design and original set of experiments that led to the research, article writing, and revisions	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5674935	29163603	LR-Z	7	Experiments design and article discussions	Experiments design and article discussions	Conceived and designed the experiments	Methodology	YES
5674935	29163603	MS	7	Microscopy related experiments	Microscopy related experiments	Performed the experiments	Investigation	YES
5674935	29163603	PH	7	Article discussions and review	Article discussions and review	-	-	NO
5674935	29163603	UR-C	7	Experiments design and conception and wrote the article	Experiments design and conception and wrote the article	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
2276184	18269769	JM	2	organized the blood collection and assayed the samples	organized the blood collection and assayed the samples	Performed the experiments	Investigation	YES
2276184	18269769	KL	2	organized the blood collection and assayed the samples	organized the blood collection and assayed the samples	Performed the experiments	Investigation	YES
2276184	18269769	KRG	2	participated in the design of the study	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
2276184	18269769	MP	2	participated in the design of the study	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
2276184	18269769	NM	2	participated in the design of the study|organized the blood collection and assayed the samples|drafted the manuscript	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
2276184	18269769	NM	2	participated in the design of the study|organized the blood collection and assayed the samples|drafted the manuscript	organized the blood collection and assayed the samples	Performed the experiments	Investigation	YES
2276184	18269769	NM	2	participated in the design of the study|organized the blood collection and assayed the samples|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
2276184	18269769	RJ	2	participated in the design of the study|drafted the manuscript	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
2276184	18269769	RJ	2	participated in the design of the study|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
2276184	18269769	VS	2	organized the blood collection and assayed the samples	organized the blood collection and assayed the samples	Performed the experiments	Investigation	YES
4980858	27515445	FXB	2	participated in the imaging analysis	participated in the imaging analysis	Analyzed the data	Visualization	YES
4980858	27515445	HB	2	participated in the imaging analysis	participated in the imaging analysis	Analyzed the data	Visualization	YES
4980858	27515445	JM	2	carried out the study design, all imaging data acquisition and analysis and the writing of the manuscript	carried out the study design, all imaging data acquisition and analysis and the writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Visualization|Writing - Original Draft	YES
4980858	27515445	SAE	2	particiapted in study design	particiapted in study design	Conceived and designed the experiments	Methodology	YES
4980858	27515445	STB	2	was involved in the study design, project management of azd8186 and the writing of the manuscript	was involved in the study design, project management of azd8186 and the writing of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft	YES
4980858	27515445	UH	2	participated and was involved in project management of azd8186	participated and was involved in project management of azd8186	-	Project administration	YES
4980858	27515445	UP	2	in the writing of the manuscript	in the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5523153	28738802	AF	2	performed the zebrafish histology	performed the zebrafish histology	Performed the experiments	Investigation	YES
5523153	28738802	JH	2	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5523153	28738802	KR	2	assisted with the analysed and interpreted the rna seq data with the	assisted with the analysed and interpreted the rna seq data with the	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5523153	28738802	MB	2	designed the experiments|assisted with the analysed and interpreted the rna seq data with the	designed the experiments	Conceived and designed the experiments	Methodology	YES
5523153	28738802	MB	2	designed the experiments|assisted with the analysed and interpreted the rna seq data with the	assisted with the analysed and interpreted the rna seq data with the	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5523153	28738802	NG	2	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5523153	28738802	SL	2	designed the experiments|performed the treatments, sample collection and laboratory work|analysed and interpreted the rna seq data with the	designed the experiments	Conceived and designed the experiments	Methodology	YES
5523153	28738802	SL	2	designed the experiments|performed the treatments, sample collection and laboratory work|analysed and interpreted the rna seq data with the	performed the treatments, sample collection and laboratory work	Performed the experiments	Investigation	YES
5523153	28738802	SL	2	designed the experiments|performed the treatments, sample collection and laboratory work|analysed and interpreted the rna seq data with the	analysed and interpreted the rna seq data with the	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
1838569	17406664	BS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1838569	17406664	BS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1838569	17406664	BS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1838569	17406664	BS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1838569	17406664	LG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1838569	17406664	LG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1838569	17406664	OL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1838569	17406664	OL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1838569	17406664	OL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1838569	17406664	OL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1838569	17406664	RV	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1838569	17406664	RV	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1838569	17406664	SA	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1838569	17406664	SA	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4411148	25915406	HL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4411148	25915406	HL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411148	25915406	HSJ	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4411148	25915406	HSJ	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411148	25915406	JEO	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411148	25915406	JN	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411148	25915406	JSL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411148	25915406	JSL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411148	25915406	JSL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411148	25915406	JSL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411148	25915406	KSP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411148	25915406	KSP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411148	25915406	KSP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411148	25915406	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411148	25915406	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411148	25915406	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411148	25915406	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411148	25915406	SSC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411148	25915406	SSC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411148	25915406	SSC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2276475	18289388	CMK	7	principal investigator of the study who obtained grant funds for project, supervised data collection and analysis, supervised statistical analyses, and co-authored paper	principal investigator of the study who obtained grant funds for project, supervised data collection and analysis, supervised statistical analyses, and co-authored paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Funding acquisition|Investigation|Supervision|Writing - Original Draft	YES
2276475	18289388	JRS	7	secondary author who helped obtain grant funds for the project	secondary author who helped obtain grant funds for the project	-	Funding acquisition	YES
2276475	18289388	MDR	7	manuscript preparation, recruitment, data analysis, statistical analysis	manuscript preparation, recruitment, data analysis, statistical analysis	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
2276475	18289388	VJD	7	primary author, recruitment, data analysis, statistical analysis and manuscript preparation	primary author, recruitment, data analysis, statistical analysis and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
1838920	17426811	AO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1838920	17426811	AO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1838920	17426811	AO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1838920	17426811	AO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1838920	17426811	AO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1838920	17426811	AR	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1838920	17426811	AR	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1838920	17426811	AR	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1838920	17426811	AR	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1838920	17426811	OK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1838920	17426811	OK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1838920	17426811	OK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1838920	17426811	OK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1838920	17426811	OK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6335296	30530543	H.K.M.T.	2	installation performed by all authors	installation performed by all authors	Performed the experiments	Investigation	YES
6335296	30530543	L.O.	2	wrote the manuscript|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6335296	30530543	L.O.	2	wrote the manuscript|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6335296	30530543	MMOS	2	installation performed by all authors	installation performed by all authors	Performed the experiments	Investigation	YES
4411149	25915488	FJB	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Manuscript approval	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411149	25915488	FJB	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Manuscript approval	Performed the experiments	Performed the experiments	Investigation	YES
4411149	25915488	FJB	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Manuscript approval	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411149	25915488	FJB	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Manuscript approval	Manuscript approval	-	-	NO
4411149	25915488	JAP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Manuscript revision|Manuscript approval	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411149	25915488	JAP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Manuscript revision|Manuscript approval	Performed the experiments	Performed the experiments	Investigation	YES
4411149	25915488	JAP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Manuscript revision|Manuscript approval	Analyzed the data	Analyzed the data	Formal analysis	YES
4411149	25915488	JAP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Manuscript revision|Manuscript approval	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411149	25915488	JAP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Manuscript revision|Manuscript approval	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411149	25915488	JAP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Manuscript revision|Manuscript approval	Manuscript revision	Wrote the paper	Writing - Review & Editing	YES
4411149	25915488	JAP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Manuscript revision|Manuscript approval	Manuscript approval	-	-	NO
4411149	25915488	JPF	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Manuscript revision|Manuscript approval	Performed the experiments	Performed the experiments	Investigation	YES
4411149	25915488	JPF	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Manuscript revision|Manuscript approval	Analyzed the data	Analyzed the data	Formal analysis	YES
4411149	25915488	JPF	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Manuscript revision|Manuscript approval	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411149	25915488	JPF	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Manuscript revision|Manuscript approval	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411149	25915488	JPF	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Manuscript revision|Manuscript approval	Manuscript revision	Wrote the paper	Writing - Review & Editing	YES
4411149	25915488	JPF	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Manuscript revision|Manuscript approval	Manuscript approval	-	-	NO
4411149	25915488	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Supervised housing and daily care of subjects|Manuscript revision|Manuscript approval	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411149	25915488	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Supervised housing and daily care of subjects|Manuscript revision|Manuscript approval	Performed the experiments	Performed the experiments	Investigation	YES
4411149	25915488	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Supervised housing and daily care of subjects|Manuscript revision|Manuscript approval	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411149	25915488	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Supervised housing and daily care of subjects|Manuscript revision|Manuscript approval	Supervised housing and daily care of subjects	-	Supervision	YES
4411149	25915488	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Supervised housing and daily care of subjects|Manuscript revision|Manuscript approval	Manuscript revision	Wrote the paper	Writing - Review & Editing	YES
4411149	25915488	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Supervised housing and daily care of subjects|Manuscript revision|Manuscript approval	Manuscript approval	-	-	NO
4980865	27515447	AH	2	contributed to the study design, preparation of the study, conducting of the measurements, analyzing of the data, drafting of the manuscript, and critical revision of the manuscript	contributed to the study design, preparation of the study, conducting of the measurements, analyzing of the data, drafting of the manuscript, and critical revision of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
4980865	27515447	AT	2	contributed to the preparation of the study, conducting of the measurements, and analyzing of the data	contributed to the preparation of the study, conducting of the measurements, and analyzing of the data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
4980865	27515447	CW	2	contributed to the preparation of the study, conducting of the measurements, and analyzing of the data	contributed to the preparation of the study, conducting of the measurements, and analyzing of the data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
4980865	27515447	FG	2	contributed to the preparation of the study, conducting of the measurements, and analyzing of the data	contributed to the preparation of the study, conducting of the measurements, and analyzing of the data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
4980865	27515447	HI	2	contributed to the study design, preparation of the study, conducting of the measurements, analyzing of the data, drafting of the manuscript, and critical revision of the manuscript	contributed to the study design, preparation of the study, conducting of the measurements, analyzing of the data, drafting of the manuscript, and critical revision of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
4980865	27515447	HW	2	contributed to the preparation of the study, conducting of the measurements, and analyzing of the data	contributed to the preparation of the study, conducting of the measurements, and analyzing of the data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
4980865	27515447	JS	2	contributed to the preparation of the study, conducting of the measurements, and analyzing of the data	contributed to the preparation of the study, conducting of the measurements, and analyzing of the data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
4980865	27515447	MH	2	contributed to the study design, drafting of the manuscript, and critical revision of the manuscript	contributed to the study design, drafting of the manuscript, and critical revision of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft|Writing - Review & Editing	YES
4980865	27515447	PB	2	contributed to the study design, drafting of the manuscript, and critical revision of the manuscript	contributed to the study design, drafting of the manuscript, and critical revision of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft|Writing - Review & Editing	YES
4980865	27515447	PC	2	contributed to the preparation of the study, conducting of the measurements, and analyzing of the data	contributed to the preparation of the study, conducting of the measurements, and analyzing of the data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
4980865	27515447	TH	2	contributed to the preparation of the study, conducting of the measurements, and analyzing of the data	contributed to the preparation of the study, conducting of the measurements, and analyzing of the data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
3751892	23958155	JL	2	participated in test design and supervision, and revised the manuscript|participated in the statistics analysis	participated in test design and supervision, and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Supervision|Writing - Review & Editing	YES
3751892	23958155	JL	2	participated in test design and supervision, and revised the manuscript|participated in the statistics analysis	participated in the statistics analysis	Analyzed the data	Formal analysis	YES
3751892	23958155	LQJ	2	conceived the study|carried out pretreatment, hydrolysis and fermentation experiments, and drafted manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
3751892	23958155	LQJ	2	conceived the study|carried out pretreatment, hydrolysis and fermentation experiments, and drafted manuscript	carried out pretreatment, hydrolysis and fermentation experiments, and drafted manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3751892	23958155	ZF	2	conceived the study|participated in test design and supervision, and revised the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
3751892	23958155	ZF	2	conceived the study|participated in test design and supervision, and revised the manuscript	participated in test design and supervision, and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Supervision|Writing - Review & Editing	YES
5525234	28738779	MM	2	performed the research|populated the database	performed the research	Performed the experiments	Investigation	YES
5525234	28738779	MM	2	performed the research|populated the database	populated the database	Contributed reagents/materials/analysis tools	Software	YES
5525234	28738779	MV	2	populated the database	populated the database	Contributed reagents/materials/analysis tools	Software	YES
5525234	28738779	RS	2	conceived and designed the research	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5675891	29163580	G-ZH	2	did the experimental work	did the experimental work	Performed the experiments	Investigation	YES
5675891	29163580	HR	2	conceived the study, designed the experiments, and wrote the manuscript	conceived the study, designed the experiments, and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
5675891	29163580	MJ	2	did the experimental work	did the experimental work	Performed the experiments	Investigation	YES
5675891	29163580	MU	2	conceived the study, designed the experiments, and wrote the manuscript|did the experimental work	conceived the study, designed the experiments, and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
5675891	29163580	MU	2	conceived the study, designed the experiments, and wrote the manuscript|did the experimental work	did the experimental work	Performed the experiments	Investigation	YES
1838921	17426812	AJ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1838921	17426812	AW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1838921	17426812	CL	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1838921	17426812	CL	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1838921	17426812	DN	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1838921	17426812	DN	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1838921	17426812	IB	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1838921	17426812	IB	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1838921	17426812	JL	PLoS5	Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1838921	17426812	JL	PLoS5	Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1838921	17426812	NL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1838921	17426812	PJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1838921	17426812	PJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1838921	17426812	PJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1838921	17426812	PT	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2288589	18302755	LMV	2	participated in the implementation of the study, assisted in carrying out the immunoassays, and drafted the manuscript	participated in the implementation of the study, assisted in carrying out the immunoassays, and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
2288589	18302755	MAP	2	participated in the implementation of the study and assisted in carrying out the immunoassays	participated in the implementation of the study and assisted in carrying out the immunoassays	Performed the experiments	Investigation	YES
2288589	18302755	NRR	2	participated in the study design and helped draft the manuscript	participated in the study design and helped draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
2288589	18302755	PCG	2	conceived of the study, participated in its design and coordination, carried out the immunoassays, performed the statistical analyses, and helped draft the manuscript	conceived of the study, participated in its design and coordination, carried out the immunoassays, performed the statistical analyses, and helped draft the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Project administration|Writing - Original Draft	YES
2288589	18302755	WFM	2	participated in the implementation of the study and assisted in carrying out the immunoassays	participated in the implementation of the study and assisted in carrying out the immunoassays	Performed the experiments	Investigation	YES
4411150	25915400	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411150	25915400	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411150	25915400	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411150	25915400	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411150	25915400	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411150	25915400	MJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411150	25915400	MJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411150	25915400	MJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411150	25915400	MJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411150	25915400	MJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411150	25915400	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411150	25915400	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411150	25915400	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411150	25915400	TK	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411150	25915400	TK	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411150	25915400	TK	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411150	25915400	TK	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4987764	27518873	All authors	PLoS52	were involved in the overall design of the studies and critically reviewed and approved the manuscript	were involved in the overall design of the studies and critically reviewed and approved the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
4987764	27518873	GF	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
4987764	27518873	LJ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
4987764	27518873	MB	PLoS52	performed the experiments|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
4987764	27518873	MB	PLoS52	performed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6335480	30966939	K.V.C.	2	conceived of the review topic|together wrote the introductory and concluding material|was responsible for the sections on mafic arc volcanism	conceived of the review topic	Conceived and designed the experiments	Conceptualization	YES
6335480	30966939	K.V.C.	2	conceived of the review topic|together wrote the introductory and concluding material|was responsible for the sections on mafic arc volcanism	together wrote the introductory and concluding material	Wrote the paper	Writing - Original Draft	YES
6335480	30966939	K.V.C.	2	conceived of the review topic|together wrote the introductory and concluding material|was responsible for the sections on mafic arc volcanism	was responsible for the sections on mafic arc volcanism	-	-	NO
6335480	30966939	M.E.	2	together wrote the introductory and concluding material	together wrote the introductory and concluding material	Wrote the paper	Writing - Original Draft	YES
5675896	29163617	AC	2	conceived the project and research plan and designed the experiments|performed most of the experiments, analyzed the data, and wrote the manuscript	conceived the project and research plan and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5675896	29163617	AC	2	conceived the project and research plan and designed the experiments|performed most of the experiments, analyzed the data, and wrote the manuscript	performed most of the experiments, analyzed the data, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5675896	29163617	AV	2	conceived the project and research plan and designed the experiments	conceived the project and research plan and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5675896	29163617	JA	2	provided technical support and data analyses and performed some of the experiments	provided technical support and data analyses and performed some of the experiments	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5675896	29163617	JR	2	provided technical support and data analyses and performed some of the experiments	provided technical support and data analyses and performed some of the experiments	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5675896	29163617	OS	2	provided technical support and data analyses and performed some of the experiments	provided technical support and data analyses and performed some of the experiments	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5675896	29163617	RS	2	provided technical support and data analyses and performed some of the experiments	provided technical support and data analyses and performed some of the experiments	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5675896	29163617	TM	2	provided technical support and data analyses and performed some of the experiments	provided technical support and data analyses and performed some of the experiments	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
3751922	23958081	AU	2	supervised experimental design and revised the manuscript for submission	supervised experimental design and revised the manuscript for submission	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Review & Editing	YES
3751922	23958081	BSD	2	carried out the technical guidance	carried out the technical guidance	Performed the experiments	Investigation|Supervision	YES
3751922	23958081	KU	2	participated in analysis of bacterial communities and contributed valuable suggestions to the study	participated in analysis of bacterial communities and contributed valuable suggestions to the study	-	-	NO
3751922	23958081	NK	2	conducted the technical guidance for cloning of the genes and drawing of the phylogenetic trees	conducted the technical guidance for cloning of the genes and drawing of the phylogenetic trees	Performed the experiments	Investigation|Supervision	YES
3751922	23958081	SM	2	carried out the molecular studies of soil bacterial communities and drafted the manuscript	carried out the molecular studies of soil bacterial communities and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3751922	23958081	TI	2	carried out soil treatments, crop cultivation, and sampling of soil	carried out soil treatments, crop cultivation, and sampling of soil	Performed the experiments	Investigation	YES
1838922	17426814	AA	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1838922	17426814	AA	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1838922	17426814	AA	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1838922	17426814	DG	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1838922	17426814	DG	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1838922	17426814	DG	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1838922	17426814	GE	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1838922	17426814	GE	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1838922	17426814	HC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1838922	17426814	KG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1838922	17426814	KG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1838922	17426814	KG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1838922	17426814	SM	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1838922	17426814	ZP	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1838922	17426814	ZP	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4411151	25915686	HIJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411151	25915686	HIJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411151	25915686	HIJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411151	25915686	HIJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411151	25915686	JAC	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411151	25915686	JAJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411151	25915686	JAJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411151	25915686	JAJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6335484	30966926	C.A.	2	set up and performed the numerical models|set up and performed the numerical models	set up and performed the numerical models	Performed the experiments	Formal analysis|Investigation|Methodology	YES
6335484	30966926	C.A.	2	set up and performed the numerical models|set up and performed the numerical models	set up and performed the numerical models	Performed the experiments	Formal analysis|Investigation|Methodology	YES
5676210	29163611	GL	PLoS52	provided the research materials	provided the research materials	Contributed reagents/materials/analysis tools	Resources	YES
5676210	29163611	HW	PLoS52	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5676210	29163611	JS	PLoS52	designed the experiments|analyzed the data|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5676210	29163611	JS	PLoS52	designed the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5676210	29163611	JS	PLoS52	designed the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5676210	29163611	JZ	PLoS52	collected the phenotypic data	collected the phenotypic data	Performed the experiments	Investigation	YES
5676210	29163611	XW	PLoS52	provided the research materials	provided the research materials	Contributed reagents/materials/analysis tools	Resources	YES
5676210	29163611	YW	PLoS52	performed cytological experiments|wrote the manuscript	performed cytological experiments	Performed the experiments	Investigation	YES
5676210	29163611	YW	PLoS52	performed cytological experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5676210	29163611	YY	PLoS52	performed the genetic experiments|performed cytological experiments|analyzed the data|wrote the manuscript	performed the genetic experiments	Performed the experiments	Investigation	YES
5676210	29163611	YY	PLoS52	performed the genetic experiments|performed cytological experiments|analyzed the data|wrote the manuscript	performed cytological experiments	Performed the experiments	Investigation	YES
5676210	29163611	YY	PLoS52	performed the genetic experiments|performed cytological experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5676210	29163611	YY	PLoS52	performed the genetic experiments|performed cytological experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5020033	27620458	DS	2	participated in the data investigation	participated in the data investigation	Performed the experiments	Investigation	YES
5020033	27620458	EI	2	designed the study, performed the analyses, and wrote the manuscript	designed the study, performed the analyses, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5020033	27620458	HM	2	supervised the study and helped to draft the manuscript	supervised the study and helped to draft the manuscript	Wrote the paper	Supervision|Writing - Original Draft	YES
5020033	27620458	KS	2	participated in the data investigation	participated in the data investigation	Performed the experiments	Investigation	YES
5020033	27620458	KY	2	assembled the data	assembled the data	-	-	NO
5020033	27620458	MM	2	gave conceptual advice	gave conceptual advice	Conceived and designed the experiments	Conceptualization	YES
5020033	27620458	NS	2	gave technical support	gave technical support	Performed the experiments	Investigation	YES
5020033	27620458	TT	2	carried out the patient management	carried out the patient management	Performed the experiments	Investigation	YES
5020033	27620458	YK	2	participated in the data investigation	participated in the data investigation	Performed the experiments	Investigation	YES
5525251	28738780	CYM	2	participated in the sample collection	participated in the sample collection	Performed the experiments	Investigation	YES
5525251	28738780	FXG	2	performed laboratory experiments, analyzed the data and drafted the manuscript	performed laboratory experiments, analyzed the data and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5525251	28738780	JFG	2	conceived the study and revised the manuscript	conceived the study and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5525251	28738780	LZ	2	designed the studies, analyzed the data, and drafted the manuscript	designed the studies, analyzed the data, and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5525251	28738780	QYZ	2	conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5525251	28738780	YW	2	participated in the data analysis and revised manuscript	participated in the data analysis and revised manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5525251	28738780	ZL	2	participated in the sample collection	participated in the sample collection	Performed the experiments	Investigation	YES
4573233	26421295	Lei Zhang	2	contributed equally	contributed equally	-	-	NO
4573233	26421295	Wenshi Yin	2	contributed equally	contributed equally	-	-	NO
2315638	18318910	Brian Leutholtz	2	assisted in research design and consultation	assisted in research design and consultation	Conceived and designed the experiments	-	YES
2315638	18318910	Brian Shelmadine	2	assisted in data collection	assisted in data collection	Performed the experiments	Investigation	YES
2315638	18318910	Chad Kerksick	2	assisted in data collection	assisted in data collection	Performed the experiments	Investigation	YES
2315638	18318910	Chris Rasmussen	2	is director of the exercise and sport nutrition lab	is director of the exercise and sport nutrition lab	-	-	NO
2315638	18318910	Darryn Willoughby	2	assisted in research design and consultation	assisted in research design and consultation	Conceived and designed the experiments	-	YES
2315638	18318910	Geoffrey Hudson	2	assisted in data collection	assisted in data collection	Performed the experiments	Investigation	YES
2315638	18318910	Matthew Cooke	2	assisted in designing the study, writing the grant, study coordination, data analysis, and manuscript preparation	assisted in designing the study, writing the grant, study coordination, data analysis, and manuscript preparation	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Project administration|Writing - Original Draft	YES
2315638	18318910	Mike Greenwood	2	assisted in research design and consultation	assisted in research design and consultation	Conceived and designed the experiments	-	YES
2315638	18318910	Mike Iosia	2	assisted in data collection and supervision of the study	assisted in data collection and supervision of the study	Performed the experiments	Investigation|Supervision	YES
2315638	18318910	PI	2	of study	of study	-	-	NO
2315638	18318910	Thomas Buford	2	assisted in data collection	assisted in data collection	Performed the experiments	Investigation	YES
1838923	17426815	AR	CRediT	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Critical revision of the manuscript|Supervision|Administrative support|Technical support	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1838923	17426815	AR	CRediT	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Critical revision of the manuscript|Supervision|Administrative support|Technical support	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1838923	17426815	AR	CRediT	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Critical revision of the manuscript|Supervision|Administrative support|Technical support	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1838923	17426815	AR	CRediT	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Critical revision of the manuscript|Supervision|Administrative support|Technical support	Critical revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
1838923	17426815	AR	CRediT	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Critical revision of the manuscript|Supervision|Administrative support|Technical support	Supervision	-	Supervision	YES
1838923	17426815	AR	CRediT	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Critical revision of the manuscript|Supervision|Administrative support|Technical support	Administrative support	-	Project administration	YES
1838923	17426815	AR	CRediT	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Critical revision of the manuscript|Supervision|Administrative support|Technical support	Technical support	Performed the experiments	Investigation	YES
1838923	17426815	BT	CRediT	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Supervised conduct of the study	Performed the experiments	Performed the experiments	Investigation	YES
1838923	17426815	BT	CRediT	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Supervised conduct of the study	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1838923	17426815	BT	CRediT	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Supervised conduct of the study	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1838923	17426815	BT	CRediT	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Supervised conduct of the study	Supervised conduct of the study	Performed the experiments	Investigation|Supervision	YES
1838923	17426815	JT	CRediT	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Critical revision of the manuscript|Supervision|Technical support	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1838923	17426815	JT	CRediT	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Critical revision of the manuscript|Supervision|Technical support	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1838923	17426815	JT	CRediT	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Critical revision of the manuscript|Supervision|Technical support	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1838923	17426815	JT	CRediT	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Critical revision of the manuscript|Supervision|Technical support	Critical revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
1838923	17426815	JT	CRediT	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Critical revision of the manuscript|Supervision|Technical support	Supervision	-	Supervision	YES
1838923	17426815	JT	CRediT	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Critical revision of the manuscript|Supervision|Technical support	Technical support	Performed the experiments	Investigation	YES
1838923	17426815	MP	CRediT	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Critical revision of the manuscript|Supervision|Technical support	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1838923	17426815	MP	CRediT	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Critical revision of the manuscript|Supervision|Technical support	Analyzed the data	Analyzed the data	Formal analysis	YES
1838923	17426815	MP	CRediT	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Critical revision of the manuscript|Supervision|Technical support	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1838923	17426815	MP	CRediT	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Critical revision of the manuscript|Supervision|Technical support	Critical revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
1838923	17426815	MP	CRediT	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Critical revision of the manuscript|Supervision|Technical support	Supervision	-	Supervision	YES
1838923	17426815	MP	CRediT	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Critical revision of the manuscript|Supervision|Technical support	Technical support	Performed the experiments	Investigation	YES
1838923	17426815	NP	CRediT	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Critical revision of the manuscript|Lead investigator	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1838923	17426815	NP	CRediT	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Critical revision of the manuscript|Lead investigator	Performed the experiments	Performed the experiments	Investigation	YES
1838923	17426815	NP	CRediT	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Critical revision of the manuscript|Lead investigator	Analyzed the data	Analyzed the data	Formal analysis	YES
1838923	17426815	NP	CRediT	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Critical revision of the manuscript|Lead investigator	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1838923	17426815	NP	CRediT	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Critical revision of the manuscript|Lead investigator	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1838923	17426815	NP	CRediT	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Critical revision of the manuscript|Lead investigator	Critical revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
1838923	17426815	NP	CRediT	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Critical revision of the manuscript|Lead investigator	Lead investigator	-	-	NO
1838923	17426815	PN	CRediT	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Critical revision of the manuscript|Supervision|Administrative support|Technical support	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1838923	17426815	PN	CRediT	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Critical revision of the manuscript|Supervision|Administrative support|Technical support	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1838923	17426815	PN	CRediT	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Critical revision of the manuscript|Supervision|Administrative support|Technical support	Critical revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
1838923	17426815	PN	CRediT	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Critical revision of the manuscript|Supervision|Administrative support|Technical support	Supervision	-	Supervision	YES
1838923	17426815	PN	CRediT	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Critical revision of the manuscript|Supervision|Administrative support|Technical support	Administrative support	-	Project administration	YES
1838923	17426815	PN	CRediT	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Critical revision of the manuscript|Supervision|Administrative support|Technical support	Technical support	Performed the experiments	Investigation	YES
1838923	17426815	RJ	CRediT	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Critical revision of the manuscript|Manager	Performed the experiments	Performed the experiments	Investigation	YES
1838923	17426815	RJ	CRediT	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Critical revision of the manuscript|Manager	Analyzed the data	Analyzed the data	Formal analysis	YES
1838923	17426815	RJ	CRediT	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Critical revision of the manuscript|Manager	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1838923	17426815	RJ	CRediT	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Critical revision of the manuscript|Manager	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1838923	17426815	RJ	CRediT	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Critical revision of the manuscript|Manager	Critical revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
1838923	17426815	RJ	CRediT	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Critical revision of the manuscript|Manager	Manager	-	Project administration	YES
1838923	17426815	SD	CRediT	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Critical revision of the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
1838923	17426815	SD	CRediT	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Critical revision of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
1838923	17426815	SD	CRediT	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Critical revision of the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1838923	17426815	SD	CRediT	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Critical revision of the manuscript	Critical revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
1838923	17426815	SK	CRediT	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Critical revision of the manuscript|Supervision|Administrative support	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1838923	17426815	SK	CRediT	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Critical revision of the manuscript|Supervision|Administrative support	Analyzed the data	Analyzed the data	Formal analysis	YES
1838923	17426815	SK	CRediT	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Critical revision of the manuscript|Supervision|Administrative support	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1838923	17426815	SK	CRediT	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Critical revision of the manuscript|Supervision|Administrative support	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1838923	17426815	SK	CRediT	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Critical revision of the manuscript|Supervision|Administrative support	Critical revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
1838923	17426815	SK	CRediT	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Critical revision of the manuscript|Supervision|Administrative support	Supervision	-	Supervision	YES
1838923	17426815	SK	CRediT	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Critical revision of the manuscript|Supervision|Administrative support	Administrative support	-	Project administration	YES
5681517	29163614	All authors	2	listed, have made substantial, direct and intellectual contribution to the work, and approved it for publication	listed, have made substantial, direct and intellectual contribution to the work, and approved it for publication	-	-	NO
4411152	25915639	CM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411152	25915639	CM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411152	25915639	CM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411152	25915639	CM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411152	25915639	JC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411152	25915639	JC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411152	25915639	JC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411152	25915639	JC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411152	25915639	JC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411152	25915639	JSA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411152	25915639	JSA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411152	25915639	JSA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411152	25915639	JSA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411152	25915639	JSA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411152	25915639	TM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411152	25915639	TM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411152	25915639	TM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411152	25915639	TS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411152	25915639	TS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411152	25915639	TS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411152	25915639	TS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411152	25915639	TS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5525271	28738828	HLT	2	designed the experiments|conducted experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5525271	28738828	HLT	2	designed the experiments|conducted experiments	conducted experiments	Performed the experiments	Investigation	YES
5525271	28738828	MCL	2	designed the experiments|conducted experiments|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5525271	28738828	MCL	2	designed the experiments|conducted experiments|wrote the manuscript	conducted experiments	Performed the experiments	Investigation	YES
5525271	28738828	MCL	2	designed the experiments|conducted experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5525271	28738828	SHW	2	designed the experiments|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5525271	28738828	SHW	2	designed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5525271	28738828	SLL	2	conducted experiments	conducted experiments	Performed the experiments	Investigation	YES
5525271	28738828	STJ	2	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5030203	27650280	AS	2	designed the imaging protocol and assisted in image acquisition|prepared the manuscript	designed the imaging protocol and assisted in image acquisition	Conceived and designed the experiments|Analyzed the data	Methodology|Visualization	YES
5030203	27650280	AS	2	designed the imaging protocol and assisted in image acquisition|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5030203	27650280	CL	2	designed the imaging protocol and assisted in image acquisition|prepared the manuscript	designed the imaging protocol and assisted in image acquisition	Conceived and designed the experiments|Analyzed the data	Methodology|Visualization	YES
5030203	27650280	CL	2	designed the imaging protocol and assisted in image acquisition|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5030203	27650280	EA	2	designed the imaging protocol and assisted in image acquisition	designed the imaging protocol and assisted in image acquisition	Conceived and designed the experiments|Analyzed the data	Methodology|Visualization	YES
5030203	27650280	HF	2	designed the imaging protocol and assisted in image acquisition	designed the imaging protocol and assisted in image acquisition	Conceived and designed the experiments|Analyzed the data	Methodology|Visualization	YES
5030203	27650280	KF	2	performed data processing and analysis|prepared the manuscript	performed data processing and analysis	Analyzed the data	Data curation|Formal analysis	YES
5030203	27650280	KF	2	performed data processing and analysis|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5030203	27650280	MG	2	performed data processing and analysis|prepared the manuscript	performed data processing and analysis	Analyzed the data	Data curation|Formal analysis	YES
5030203	27650280	MG	2	performed data processing and analysis|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5030203	27650280	RC	2	designed the imaging protocol and assisted in image acquisition|prepared the manuscript	designed the imaging protocol and assisted in image acquisition	Conceived and designed the experiments|Analyzed the data	Methodology|Visualization	YES
5030203	27650280	RC	2	designed the imaging protocol and assisted in image acquisition|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5030203	27650280	TM	2	performed data processing and analysis|prepared the manuscript	performed data processing and analysis	Analyzed the data	Data curation|Formal analysis	YES
5030203	27650280	TM	2	performed data processing and analysis|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
2365926	18423024	AJL	2	did data collection, data entry, drafting of the manuscript and reviewing the manuscript	did data collection, data entry, drafting of the manuscript and reviewing the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
2365926	18423024	DA	2	did data collection and critically reviewed the manuscript	did data collection and critically reviewed the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
2365926	18423024	DB	2	participated in study design and data collection	participated in study design and data collection	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
2365926	18423024	GB	2	did data collection and critically reviewed the manuscript	did data collection and critically reviewed the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
2365926	18423024	JAB	2	is the principal investigator of the study, conducted data collection, drafting and critically evaluating the manuscript	is the principal investigator of the study, conducted data collection, drafting and critically evaluating the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Funding acquisition|Investigation|Writing - Original Draft	YES
2365926	18423024	MK	2	did data collection and critically reviewed the manuscript	did data collection and critically reviewed the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
2365926	18423024	SVS	2	conceptualized the study question and design, conducted statistical analysis, interpretation of results, drafting of manuscript and reviewing of the manuscript	conceptualized the study question and design, conducted statistical analysis, interpretation of results, drafting of manuscript and reviewing of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
1847532	17440608	AA	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1847532	17440608	AA	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1847532	17440608	AL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1847532	17440608	AL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1847532	17440608	AL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1847532	17440608	AL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1847532	17440608	EF	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1847532	17440608	EF	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1847532	17440608	JP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1847532	17440608	JP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1847532	17440608	JP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1847532	17440608	MP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1847532	17440608	MP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1847532	17440608	MP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1847532	17440608	MP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1847532	17440608	NB	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1847532	17440608	NB	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1847532	17440608	SD	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1847532	17440608	SD	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4573423	26421293	Elisabeth Wischnitzki	2	performed bioinformatics analyses|drafted the paper	performed bioinformatics analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4573423	26421293	Elisabeth Wischnitzki	2	performed bioinformatics analyses|drafted the paper	drafted the paper	Wrote the paper	Writing - Original Draft	YES
4573423	26421293	Eva Maria Sehr	2	drafted the paper	drafted the paper	Wrote the paper	Writing - Original Draft	YES
4573423	26421293	Karin Hansel-Hohl	2	performed sample collection and dna extraction as well as wet lab methyl filtration experiments	performed sample collection and dna extraction as well as wet lab methyl filtration experiments	Performed the experiments	Investigation	YES
4573423	26421293	Kornel Burg	2	designed the experiment|advised in experimental design and assisted in conceptual data analysis	designed the experiment	Conceived and designed the experiments	Methodology	YES
4573423	26421293	Kornel Burg	2	designed the experiment|advised in experimental design and assisted in conceptual data analysis	advised in experimental design and assisted in conceptual data analysis	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
4573423	26421293	Maria Berenyi	2	designed the experiment|performed sample collection and dna extraction as well as wet lab methyl filtration experiments	designed the experiment	Conceived and designed the experiments	Methodology	YES
4573423	26421293	Maria Berenyi	2	designed the experiment|performed sample collection and dna extraction as well as wet lab methyl filtration experiments	performed sample collection and dna extraction as well as wet lab methyl filtration experiments	Performed the experiments	Investigation	YES
4573423	26421293	Silvia Fluch	2	designed the experiment|advised in experimental design and assisted in conceptual data analysis|coordinated the project and edited the paper	designed the experiment	Conceived and designed the experiments	Methodology	YES
4573423	26421293	Silvia Fluch	2	designed the experiment|advised in experimental design and assisted in conceptual data analysis|coordinated the project and edited the paper	advised in experimental design and assisted in conceptual data analysis	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
4573423	26421293	Silvia Fluch	2	designed the experiment|advised in experimental design and assisted in conceptual data analysis|coordinated the project and edited the paper	coordinated the project and edited the paper	Wrote the paper	Project administration|Writing - Review & Editing	YES
4411153	25915402	AGR	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411153	25915402	CNO	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411153	25915402	GFM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411153	25915402	GFM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411153	25915402	JIB	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4411153	25915402	MAB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411153	25915402	MAB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411153	25915402	MAB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411153	25915402	MAB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411153	25915402	RIB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411153	25915402	RIB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411153	25915402	TSB	PLoS5	Performed the experiment for answering the reviewers	Performed the experiment for answering the reviewers	Performed the experiments	Investigation	YES
5031577	27655427	AP	2	planned and carried out the synthesis and evaluation of the compounds	planned and carried out the synthesis and evaluation of the compounds	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5031577	27655427	HJW	2	helped in analyzing and interpreting the data and initiated and designed the study	helped in analyzing and interpreting the data and initiated and designed the study	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
5031577	27655427	MScho	2	participated in the design of the study, contributed to the data interpretation, and revised the manuscript	participated in the design of the study, contributed to the data interpretation, and revised the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
5525293	28738815	All authors	2	edited and approved the final version of the manuscript	edited and approved the final version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5525293	28738815	DBN	2	provided draft transcriptome and genome assemblies, and provided transcript annotations|gave conceptual advice on the manuscript	provided draft transcriptome and genome assemblies, and provided transcript annotations	Analyzed the data|Wrote the paper	Data curation|Formal analysis|Writing - Original Draft	YES
5525293	28738815	DBN	2	provided draft transcriptome and genome assemblies, and provided transcript annotations|gave conceptual advice on the manuscript	gave conceptual advice on the manuscript	Conceived and designed the experiments	Conceptualization	YES
5525293	28738815	DRD	2	jointly designed the study	jointly designed the study	Conceived and designed the experiments	Methodology	YES
5525293	28738815	JBS	2	collected the seed and established the common garden used in this experiment|jointly designed the study|performed experiments and collected data	collected the seed and established the common garden used in this experiment	Performed the experiments	Investigation	YES
5525293	28738815	JBS	2	collected the seed and established the common garden used in this experiment|jointly designed the study|performed experiments and collected data	jointly designed the study	Conceived and designed the experiments	Methodology	YES
5525293	28738815	JBS	2	collected the seed and established the common garden used in this experiment|jointly designed the study|performed experiments and collected data	performed experiments and collected data	Performed the experiments	Investigation	YES
5525293	28738815	JLW	2	provided draft transcriptome and genome assemblies, and provided transcript annotations|gave conceptual advice on the manuscript	provided draft transcriptome and genome assemblies, and provided transcript annotations	Analyzed the data|Wrote the paper	Data curation|Formal analysis|Writing - Original Draft	YES
5525293	28738815	JLW	2	provided draft transcriptome and genome assemblies, and provided transcript annotations|gave conceptual advice on the manuscript	gave conceptual advice on the manuscript	Conceived and designed the experiments	Conceptualization	YES
5525293	28738815	PCD	2	jointly designed the study|performed experiments and collected data|analyzed data	jointly designed the study	Conceived and designed the experiments	Methodology	YES
5525293	28738815	PCD	2	jointly designed the study|performed experiments and collected data|analyzed data	performed experiments and collected data	Performed the experiments	Investigation	YES
5525293	28738815	PCD	2	jointly designed the study|performed experiments and collected data|analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5525293	28738815	RCC	2	jointly designed the study|performed experiments and collected data|analyzed data	jointly designed the study	Conceived and designed the experiments	Methodology	YES
5525293	28738815	RCC	2	jointly designed the study|performed experiments and collected data|analyzed data	performed experiments and collected data	Performed the experiments	Investigation	YES
5525293	28738815	RCC	2	jointly designed the study|performed experiments and collected data|analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5525293	28738815	SH	2	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5525293	28738815	SJ	2	provided draft transcriptome and genome assemblies, and provided transcript annotations	provided draft transcriptome and genome assemblies, and provided transcript annotations	Analyzed the data|Wrote the paper	Data curation|Formal analysis|Writing - Original Draft	YES
2500001	18652668	JO	2	assisted in study coordination, supervision and data collection	assisted in study coordination, supervision and data collection	Performed the experiments	Investigation|Project administration|Supervision	YES
2500001	18652668	MLA	2	assisted in protocol development, clinical supply management and manuscript preparation	assisted in protocol development, clinical supply management and manuscript preparation	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
2500001	18652668	SCK	2	assisted in protocol development, data management and statistical analysis	assisted in protocol development, data management and statistical analysis	Conceived and designed the experiments|Analyzed the data	Data curation|Formal analysis|Methodology	YES
3817633	24235889	All authors	2	read and approved the final paper	read and approved the final paper	-	-	NO
3817633	24235889	Conchita Martin	2	was involved in drafting the paper, performing statistical analysis, and making substantial contributions to interpretation of data	was involved in drafting the paper, performing statistical analysis, and making substantial contributions to interpretation of data	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
3817633	24235889	Domenico Dalessandri	2	conceived the study, participated in its design and coordination, performed the experimental part, and wrote the paper	conceived the study, participated in its design and coordination, performed the experimental part, and wrote the paper	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Project administration|Writing - Original Draft	YES
3817633	24235889	Luca Contardo	2	was involved in selecting and performing statistical analysis	was involved in selecting and performing statistical analysis	Analyzed the data	Formal analysis	YES
3817633	24235889	Luca Visconti	2	were involved in revising the paper critically for important intellectual content	were involved in revising the paper critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
3817633	24235889	Marco Migliorati	2	participated in the design and performed the experimental part	participated in the design and performed the experimental part	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3817633	24235889	Rachele Rubiano	2	participated in the design and performed the experimental part	participated in the design and performed the experimental part	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3817633	24235889	Roberto Di Lenarda	2	were involved in revising the paper critically for important intellectual content	were involved in revising the paper critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5681527	29163558	N. All	2	authors read and approved the final manuscript	authors read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
1847533	17440609	CC	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1847533	17440609	CC	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1847533	17440609	CS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1847533	17440609	CS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1847533	17440609	CS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1847533	17440609	EP	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1847533	17440609	EP	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1847533	17440609	MD	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Analyzed the data|Wrote the paper|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1847533	17440609	MD	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Analyzed the data|Wrote the paper|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1847533	17440609	MD	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Analyzed the data|Wrote the paper|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1847533	17440609	MD	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Analyzed the data|Wrote the paper|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1847533	17440609	MD	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Analyzed the data|Wrote the paper|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1847533	17440609	MG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1847533	17440609	MM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1847533	17440609	MP	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1847533	17440609	MP	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1847533	17440609	RK	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1847533	17440609	RK	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1847533	17440609	SF	PLoS5	Performed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1847533	17440609	SF	PLoS5	Performed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1847533	17440609	SF	PLoS5	Performed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4573424	26421298	All authors	2	read, critically revised, and approved the final paper	read, critically revised, and approved the final paper	Wrote the paper	Writing - Review & Editing	YES
4573424	26421298	Anna Zhu	2	collected data and provided administrative, technical, or material support	collected data and provided administrative, technical, or material support	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Project administration|Resources	YES
4573424	26421298	Haitao Wang	2	administrated the genotyping analysis|were responsible for biospecimen and data collection	administrated the genotyping analysis	Performed the experiments	Investigation	YES
4573424	26421298	Haitao Wang	2	administrated the genotyping analysis|were responsible for biospecimen and data collection	were responsible for biospecimen and data collection	Performed the experiments	Investigation	YES
4573424	26421298	Hong Li	2	did the statistical analyses and interpreted the data	did the statistical analyses and interpreted the data	Analyzed the data	Formal analysis	YES
4573424	26421298	Huiying Liang	2	were considered to contribute equally to this work|performed data management, statistical analyses and interpretations of results and drafted the initial paper	were considered to contribute equally to this work	-	-	NO
4573424	26421298	Huiying Liang	2	were considered to contribute equally to this work|performed data management, statistical analyses and interpretations of results and drafted the initial paper	performed data management, statistical analyses and interpretations of results and drafted the initial paper	Analyzed the data|Wrote the paper	Data curation|Formal analysis|Writing - Original Draft	YES
4573424	26421298	Lujia Chen	2	were considered to contribute equally to this work|did the statistical analyses and interpreted the data|administrated the genotyping analysis|were responsible for biospecimen and data collection	were considered to contribute equally to this work	-	-	NO
4573424	26421298	Lujia Chen	2	were considered to contribute equally to this work|did the statistical analyses and interpreted the data|administrated the genotyping analysis|were responsible for biospecimen and data collection	did the statistical analyses and interpreted the data	Analyzed the data	Formal analysis	YES
4573424	26421298	Lujia Chen	2	were considered to contribute equally to this work|did the statistical analyses and interpreted the data|administrated the genotyping analysis|were responsible for biospecimen and data collection	administrated the genotyping analysis	Performed the experiments	Investigation	YES
4573424	26421298	Lujia Chen	2	were considered to contribute equally to this work|did the statistical analyses and interpreted the data|administrated the genotyping analysis|were responsible for biospecimen and data collection	were responsible for biospecimen and data collection	Performed the experiments	Investigation	YES
4573424	26421298	Ming Li	2	directed the study and was responsible for the study design	directed the study and was responsible for the study design	Conceived and designed the experiments	Methodology|Supervision	YES
4573424	26421298	Minying Sun	2	collected data and provided administrative, technical, or material support|were responsible for biospecimen and data collection	collected data and provided administrative, technical, or material support	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Project administration|Resources	YES
4573424	26421298	Minying Sun	2	collected data and provided administrative, technical, or material support|were responsible for biospecimen and data collection	were responsible for biospecimen and data collection	Performed the experiments	Investigation	YES
4573424	26421298	Xuexi Yang	2	were considered to contribute equally to this work|performed data management, statistical analyses and interpretations of results and drafted the initial paper	were considered to contribute equally to this work	-	-	NO
4573424	26421298	Xuexi Yang	2	were considered to contribute equally to this work|performed data management, statistical analyses and interpretations of results and drafted the initial paper	performed data management, statistical analyses and interpretations of results and drafted the initial paper	Analyzed the data|Wrote the paper	Data curation|Formal analysis|Writing - Original Draft	YES
2503954	18662395	MK	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
2503954	18662395	MP	2	participated in the design of the study|drafted the manuscript	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
2503954	18662395	MP	2	participated in the design of the study|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
2503954	18662395	MS	2	participated in the design of the study|organized the blood collection and assayed the samples, and analyzed the results statistically|drafted the manuscript	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
2503954	18662395	MS	2	participated in the design of the study|organized the blood collection and assayed the samples, and analyzed the results statistically|drafted the manuscript	organized the blood collection and assayed the samples, and analyzed the results statistically	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
2503954	18662395	MS	2	participated in the design of the study|organized the blood collection and assayed the samples, and analyzed the results statistically|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
2503954	18662395	RJ	2	participated in the design of the study|drafted the manuscript	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
2503954	18662395	RJ	2	participated in the design of the study|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
2503954	18662395	SS	2	conducted all phlebotomy and participated in the collection and assay of the samples	conducted all phlebotomy and participated in the collection and assay of the samples	Performed the experiments	Investigation	YES
5031580	27655428	AK	2	patients for evaluation	patients for evaluation	-	-	NO
5031580	27655428	All authors	2	were involved in the overall design of the studies and critically reviewed and approved the manuscript	were involved in the overall design of the studies and critically reviewed and approved the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5031580	27655428	JFL	2	recruited observers and participated in the evaluation|collected and analysed the data and wrote the manuscript	recruited observers and participated in the evaluation	Performed the experiments	Investigation	YES
5031580	27655428	JFL	2	recruited observers and participated in the evaluation|collected and analysed the data and wrote the manuscript	collected and analysed the data and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5031580	27655428	KH	2	recruited observers and participated in the evaluation	recruited observers and participated in the evaluation	Performed the experiments	Investigation	YES
4411154	25915632	AMM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411154	25915632	AMM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411154	25915632	AMM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411154	25915632	AMM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411154	25915632	BW	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4411154	25915632	BW	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411154	25915632	EM	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4411154	25915632	EM	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4411154	25915632	HR	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411154	25915632	HR	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411154	25915632	HR	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411154	25915632	JN	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4411154	25915632	JR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411154	25915632	JR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411154	25915632	JR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411154	25915632	JR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411154	25915632	LK	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4411154	25915632	LK	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4411154	25915632	ML	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4411154	25915632	ML	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411154	25915632	OM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411154	25915632	OM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411154	25915632	OM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411154	25915632	OM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411154	25915632	OT	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4411154	25915632	OT	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4411154	25915632	PO	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4411154	25915632	PT	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4411154	25915632	PT	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4411154	25915632	RK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4411154	25915632	RK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411154	25915632	RS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4411154	25915632	RS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4411154	25915632	TH	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411154	25915632	TH	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411154	25915632	TK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411154	25915632	ZB	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4411154	25915632	ZB	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4411154	25915632	ZS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4411154	25915632	ZS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1847701	17440616	DC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1847701	17440616	DC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1847701	17440616	DC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1847701	17440616	DC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1847701	17440616	YL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1847701	17440616	YL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1847701	17440616	YL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1847701	17440616	YL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1847701	17440616	YL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5526262	28743243	AP	2	assisted in interpreting the data and revised the manuscript|coordinated this study	assisted in interpreting the data and revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5526262	28743243	AP	2	assisted in interpreting the data and revised the manuscript|coordinated this study	coordinated this study	-	Project administration	YES
5526262	28743243	JD	2	designed, planed and interpreted the experimental work of this study|carried out the transcriptomic experiments|carried out all other experimental work and revised the manuscript	designed, planed and interpreted the experimental work of this study	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5526262	28743243	JD	2	designed, planed and interpreted the experimental work of this study|carried out the transcriptomic experiments|carried out all other experimental work and revised the manuscript	carried out the transcriptomic experiments	Performed the experiments	Investigation	YES
5526262	28743243	JD	2	designed, planed and interpreted the experimental work of this study|carried out the transcriptomic experiments|carried out all other experimental work and revised the manuscript	carried out all other experimental work and revised the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5526262	28743243	JK	2	assisted in interpreting the data and revised the manuscript|coordinated this study	assisted in interpreting the data and revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5526262	28743243	JK	2	assisted in interpreting the data and revised the manuscript|coordinated this study	coordinated this study	-	Project administration	YES
5526262	28743243	SSB	2	assisted in interpreting the data and revised the manuscript	assisted in interpreting the data and revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5526262	28743243	TG	2	constructed the deletion mutant	constructed the deletion mutant	Performed the experiments	Investigation	YES
5526262	28743243	TW	2	designed, planed and interpreted the experimental work of this study|constructed the deletion mutant|carried out the transcriptomic experiments|drafted the manuscript	designed, planed and interpreted the experimental work of this study	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5526262	28743243	TW	2	designed, planed and interpreted the experimental work of this study|constructed the deletion mutant|carried out the transcriptomic experiments|drafted the manuscript	constructed the deletion mutant	Performed the experiments	Investigation	YES
5526262	28743243	TW	2	designed, planed and interpreted the experimental work of this study|constructed the deletion mutant|carried out the transcriptomic experiments|drafted the manuscript	carried out the transcriptomic experiments	Performed the experiments	Investigation	YES
5526262	28743243	TW	2	designed, planed and interpreted the experimental work of this study|constructed the deletion mutant|carried out the transcriptomic experiments|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5526262	28743243	TZ	2	advised the project and was involved in revising the manuscript	advised the project and was involved in revising the manuscript	Wrote the paper	Writing - Review & Editing	YES
5526262	28743243	VO	2	constructed the deletion mutant|assisted in interpreting the data and revised the manuscript	constructed the deletion mutant	Performed the experiments	Investigation	YES
5526262	28743243	VO	2	constructed the deletion mutant|assisted in interpreting the data and revised the manuscript	assisted in interpreting the data and revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5681529	29163624	All authors	2	listed have made a substantial, direct, and intellectual contribution to the work, and approved it for publication	listed have made a substantial, direct, and intellectual contribution to the work, and approved it for publication	-	-	NO
2525623	18700016	FA	2	assisted in study coordination, supervision, protocol development, data management and statistical analysis	assisted in study coordination, supervision, protocol development, data management and statistical analysis	Conceived and designed the experiments|Analyzed the data	Data curation|Formal analysis|Methodology|Project administration|Supervision	YES
2525623	18700016	MA	2	assisted in protocol development, clinical supply management and manuscript preparation	assisted in protocol development, clinical supply management and manuscript preparation	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5039146	27678494	AN	2	recruited, consented and assessed the patients	recruited, consented and assessed the patients	Performed the experiments	Investigation	YES
5039146	27678494	CC	2	organised and performed the genotyping	organised and performed the genotyping	Performed the experiments	Investigation	YES
5039146	27678494	FT	2	helped design the study, analysed pet data and contributed to the writing of the paper	helped design the study, analysed pet data and contributed to the writing of the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5039146	27678494	MV	2	helped design the study, analysed pet data and contributed to the writing of the paper	helped design the study, analysed pet data and contributed to the writing of the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5039146	27678494	RH	2	helped design the study, assisted with the patient recruitment and contributed to the writing of the paper	helped design the study, assisted with the patient recruitment and contributed to the writing of the paper	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5039146	27678494	SR	2	was the principal investigator for this study, designed the experiment, assisted with the patient recruitment and data analysis and contributed to the writing of the paper	was the principal investigator for this study, designed the experiment, assisted with the patient recruitment and data analysis and contributed to the writing of the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Funding acquisition|Investigation|Methodology|Writing - Original Draft	YES
5039146	27678494	XX	2	organised and performed the genotyping	organised and performed the genotyping	Performed the experiments	Investigation	YES
4573432	26421306	Alejandro Gonzalez-Martinez	2	was responsible for the bioreactors field study and in silico testing of the different primers|were responsible for writing the paper|were responsible for the conformation of all tables and figures	was responsible for the bioreactors field study and in silico testing of the different primers	Performed the experiments	Formal analysis|Investigation	YES
4573432	26421306	Alejandro Gonzalez-Martinez	2	was responsible for the bioreactors field study and in silico testing of the different primers|were responsible for writing the paper|were responsible for the conformation of all tables and figures	were responsible for writing the paper	Wrote the paper	Writing - Original Draft	YES
4573432	26421306	Alejandro Gonzalez-Martinez	2	was responsible for the bioreactors field study and in silico testing of the different primers|were responsible for writing the paper|were responsible for the conformation of all tables and figures	were responsible for the conformation of all tables and figures	-	Visualization	YES
4573432	26421306	Alejandro Rodriguez-Sanchez	2	were responsible for writing the paper|were responsible for the conformation of all tables and figures	were responsible for writing the paper	Wrote the paper	Writing - Original Draft	YES
4573432	26421306	Alejandro Rodriguez-Sanchez	2	were responsible for writing the paper|were responsible for the conformation of all tables and figures	were responsible for the conformation of all tables and figures	-	Visualization	YES
4573432	26421306	Belen Rodelas	2	also were responsible for microbial ecology analysis|were responsible for writing the paper	also were responsible for microbial ecology analysis	Performed the experiments	Investigation	YES
4573432	26421306	Belen Rodelas	2	also were responsible for microbial ecology analysis|were responsible for writing the paper	were responsible for writing the paper	Wrote the paper	Writing - Original Draft	YES
4573432	26421306	Ben A. Abbas	2	was also responsible for this	was also responsible for this	-	-	NO
4573432	26421306	F. Osorio	2	were responsible for revision of the paper	were responsible for revision of the paper	Wrote the paper	Writing - Review & Editing	YES
4573432	26421306	Jesus Gonzalez-Lopez	2	were responsible for writing the paper|were responsible for revision of the paper	were responsible for writing the paper	Wrote the paper	Writing - Original Draft	YES
4573432	26421306	Jesus Gonzalez-Lopez	2	were responsible for writing the paper|were responsible for revision of the paper	were responsible for revision of the paper	Wrote the paper	Writing - Review & Editing	YES
4573432	26421306	Victoria Martinez-Toledo	2	also were responsible for microbial ecology analysis	also were responsible for microbial ecology analysis	Performed the experiments	Investigation	YES
4411155	25915617	AM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4411155	25915617	AM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411155	25915617	EM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411155	25915617	IG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411155	25915617	IG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411155	25915617	IG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411155	25915617	IG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411155	25915617	JA	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4411155	25915617	KG	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411155	25915617	LM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411155	25915617	LM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411155	25915617	LM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411155	25915617	MI	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411155	25915617	ML	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4411155	25915617	MP	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411155	25915617	MP	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411155	25915617	RP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411155	25915617	RP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411155	25915617	RP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1847702	17440617	AC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1847702	17440617	AC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1847702	17440617	AC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1847702	17440617	AC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1847702	17440617	AC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1847702	17440617	GK	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1847702	17440617	GK	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1847702	17440617	GK	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1847702	17440617	HP	PLoS5	Wrote the paper|Provided financial support and mentored the project	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1847702	17440617	HP	PLoS5	Wrote the paper|Provided financial support and mentored the project	Provided financial support and mentored the project	-	Funding acquisition|Supervision	YES
1847702	17440617	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1847702	17440617	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1847702	17440617	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1847702	17440617	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1847702	17440617	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5681534	29163625	AM	2	helped in writing and editing the manuscript|helped in the creating the snp data and gwas analysis	helped in writing and editing the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5681534	29163625	AM	2	helped in writing and editing the manuscript|helped in the creating the snp data and gwas analysis	helped in the creating the snp data and gwas analysis	Analyzed the data	Formal analysis	YES
5681534	29163625	HD	2	helped in the creating the snp data and gwas analysis	helped in the creating the snp data and gwas analysis	Analyzed the data	Formal analysis	YES
5681534	29163625	JS	2	helped in troubleshooting, provided constructive comments, suggestions and financial support to conduct the experiments	helped in troubleshooting, provided constructive comments, suggestions and financial support to conduct the experiments	Performed the experiments	Funding acquisition|Investigation	YES
5681534	29163625	KD	2	provided the protocols for cellulose content analysis and thoroughly edited the manuscript	provided the protocols for cellulose content analysis and thoroughly edited the manuscript	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Methodology|Resources|Writing - Review & Editing	YES
5681534	29163625	KG	2	provided their expert advice and suggestions to interpret the results	provided their expert advice and suggestions to interpret the results	Analyzed the data	Formal analysis	YES
5681534	29163625	PV	2	provided the genotyping data	provided the genotyping data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5681534	29163625	SK	2	performed all the experiments in the greenhouse and laboratory set up and conducted genetic, genomic, bioinformatics analyses, and wrote the manuscript	performed all the experiments in the greenhouse and laboratory set up and conducted genetic, genomic, bioinformatics analyses, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5681534	29163625	SS	2	provided the genotyping data	provided the genotyping data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5681534	29163625	XZ	2	helped in the creating the snp data and gwas analysis	helped in the creating the snp data and gwas analysis	Analyzed the data	Formal analysis	YES
5681534	29163625	ZZ	2	provided their expert advice and suggestions to interpret the results	provided their expert advice and suggestions to interpret the results	Analyzed the data	Formal analysis	YES
6388006	30967042	All authors	2	helped collect data for the survey, provided revisions for the manuscript, read and approved the manuscript	helped collect data for the survey, provided revisions for the manuscript, read and approved the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
6388006	30967042	D.G.	2	coordinated the project, wrote the main content on the analysis of added values, designed the analysis survey form and developed the scripts to convert the analysis data into figures and tables	coordinated the project, wrote the main content on the analysis of added values, designed the analysis survey form and developed the scripts to convert the analysis data into figures and tables	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Project administration|Software|Visualization|Writing - Original Draft	YES
6388006	30967042	D.S.	2	helped collect data by performing an independent literature search for multiscale computing tools	helped collect data by performing an independent literature search for multiscale computing tools	Performed the experiments	Formal analysis|Investigation	YES
5530493	28750625	ACM	1	Sample collection and data contribution	Sample collection and data contribution	Performed the experiments	Investigation	YES
5530493	28750625	AM	1	Sample collection and data contribution	Sample collection and data contribution	Performed the experiments	Investigation	YES
5530493	28750625	AVS	1	Sample collection and data contribution	Sample collection and data contribution	Performed the experiments	Investigation	YES
5530493	28750625	BH	1	Sample collection and data contribution	Sample collection and data contribution	Performed the experiments	Investigation	YES
5530493	28750625	BW	1	Sample collection and data contribution	Sample collection and data contribution	Performed the experiments	Investigation	YES
5530493	28750625	CJF	1	Sample collection and data contribution	Sample collection and data contribution	Performed the experiments	Investigation	YES
5530493	28750625	CMW	1	Sample collection and data contribution	Sample collection and data contribution	Performed the experiments	Investigation	YES
5530493	28750625	CP	1	Sample collection and data contribution	Sample collection and data contribution	Performed the experiments	Investigation	YES
5530493	28750625	DLB	1	Sample collection and data contribution	Sample collection and data contribution	Performed the experiments	Investigation	YES
5530493	28750625	EB	1	Sample collection and data contribution|Sample collection and data contribution	Sample collection and data contribution	Performed the experiments	Investigation	YES
5530493	28750625	EB	1	Sample collection and data contribution|Sample collection and data contribution	Sample collection and data contribution	Performed the experiments	Investigation	YES
5530493	28750625	GB	1	Sample collection and data contribution	Sample collection and data contribution	Performed the experiments	Investigation	YES
5530493	28750625	GKB	1	Sample collection and data contribution	Sample collection and data contribution	Performed the experiments	Investigation	YES
5530493	28750625	GL	1	Sample collection and data contribution	Sample collection and data contribution	Performed the experiments	Investigation	YES
5530493	28750625	GT	1	Sample collection and data contribution	Sample collection and data contribution	Performed the experiments	Investigation	YES
5530493	28750625	IT	1	Sample collection and data contribution	Sample collection and data contribution	Performed the experiments	Investigation	YES
5530493	28750625	JM	1	Sample collection and data contribution	Sample collection and data contribution	Performed the experiments	Investigation	YES
5530493	28750625	JNM	1	Sample collection and data contribution	Sample collection and data contribution	Performed the experiments	Investigation	YES
5530493	28750625	JRM	1	Experimental concept and design|Sample collection and data contribution|Manuscript writing and figures	Experimental concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5530493	28750625	JRM	1	Experimental concept and design|Sample collection and data contribution|Manuscript writing and figures	Sample collection and data contribution	Performed the experiments	Investigation	YES
5530493	28750625	JRM	1	Experimental concept and design|Sample collection and data contribution|Manuscript writing and figures	Manuscript writing and figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5530493	28750625	JT	1	Sample collection and data contribution	Sample collection and data contribution	Performed the experiments	Investigation	YES
5530493	28750625	LO	1	Experimental concept and design|Sample collection and data contribution	Experimental concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5530493	28750625	LO	1	Experimental concept and design|Sample collection and data contribution	Sample collection and data contribution	Performed the experiments	Investigation	YES
5530493	28750625	MEM	1	Experimental concept and design|Sample collection and data contribution|Data analysis and interpretation|Manuscript writing and figures	Experimental concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5530493	28750625	MEM	1	Experimental concept and design|Sample collection and data contribution|Data analysis and interpretation|Manuscript writing and figures	Sample collection and data contribution	Performed the experiments	Investigation	YES
5530493	28750625	MEM	1	Experimental concept and design|Sample collection and data contribution|Data analysis and interpretation|Manuscript writing and figures	Data analysis and interpretation	Analyzed the data	Formal analysis	YES
5530493	28750625	MEM	1	Experimental concept and design|Sample collection and data contribution|Data analysis and interpretation|Manuscript writing and figures	Manuscript writing and figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5530493	28750625	MS	1	Experimental concept and design|Data analysis and interpretation|Computational support	Experimental concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5530493	28750625	MS	1	Experimental concept and design|Data analysis and interpretation|Computational support	Data analysis and interpretation	Analyzed the data	Formal analysis	YES
5530493	28750625	MS	1	Experimental concept and design|Data analysis and interpretation|Computational support	Computational support	-	Formal analysis	YES
5530493	28750625	MSL	1	Sample collection and data contribution	Sample collection and data contribution	Performed the experiments	Investigation	YES
5530493	28750625	NM	1	Sample collection and data contribution	Sample collection and data contribution	Performed the experiments	Investigation	YES
5530493	28750625	OD	1	Sample collection and data contribution	Sample collection and data contribution	Performed the experiments	Investigation	YES
5530493	28750625	RF	1	Sample collection and data contribution	Sample collection and data contribution	Performed the experiments	Investigation	YES
5530493	28750625	RJS	1	Experimental concept and design|Data analysis and interpretation|Computational support|Manuscript writing and figures	Experimental concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5530493	28750625	RJS	1	Experimental concept and design|Data analysis and interpretation|Computational support|Manuscript writing and figures	Data analysis and interpretation	Analyzed the data	Formal analysis	YES
5530493	28750625	RJS	1	Experimental concept and design|Data analysis and interpretation|Computational support|Manuscript writing and figures	Computational support	-	Formal analysis	YES
5530493	28750625	RJS	1	Experimental concept and design|Data analysis and interpretation|Computational support|Manuscript writing and figures	Manuscript writing and figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5530493	28750625	SAB	1	Sample collection and data contribution	Sample collection and data contribution	Performed the experiments	Investigation	YES
5530493	28750625	SP	1	Sample collection and data contribution	Sample collection and data contribution	Performed the experiments	Investigation	YES
5530493	28750625	SR	1	Sample collection and data contribution	Sample collection and data contribution	Performed the experiments	Investigation	YES
5530493	28750625	TK	1	Sample collection and data contribution	Sample collection and data contribution	Performed the experiments	Investigation	YES
5530493	28750625	TL	1	Sample collection and data contribution	Sample collection and data contribution	Performed the experiments	Investigation	YES
5530493	28750625	VG	1	Sample collection and data contribution	Sample collection and data contribution	Performed the experiments	Investigation	YES
5530493	28750625	VJ	1	Sample collection and data contribution	Sample collection and data contribution	Performed the experiments	Investigation	YES
6179044	30284503	All	5	procedures performed in our study were in accordance with the ethical standards of the 1964 Helsinki declaration and its later amendments or comparable ethical standards	procedures performed in our study were in accordance with the ethical standards of the 1964 Helsinki declaration and its later amendments or comparable ethical standards	Performed the experiments	Investigation	YES
5052236	27709489	DG	2	participated in the study design as well as data collation and interpretation	participated in the study design as well as data collation and interpretation	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5052236	27709489	EF	2	participated in the study design as well as data collation and interpretation	participated in the study design as well as data collation and interpretation	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5052236	27709489	LB	2	participated in the study design as well as data collation and interpretation	participated in the study design as well as data collation and interpretation	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5052236	27709489	SH	2	participated in the study design as well as data collation and interpretation	participated in the study design as well as data collation and interpretation	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
1847703	17440607	T. Kiya	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1847703	17440607	T. Kiya	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1847703	17440607	T. Kiya	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1847703	17440607	T. Kiya	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1847703	17440607	T. Kubo	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1847703	17440607	T. Kunieda	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2569905	18793439	AF	2	carried out the research	carried out the research	Performed the experiments	Investigation	YES
2569905	18793439	JS	2	carried out research, oversaw project and helped write the manuscript	carried out research, oversaw project and helped write the manuscript	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Original Draft	YES
2569905	18793439	JSC	2	writing and data interpretation	writing and data interpretation	Analyzed the data|Wrote the paper	Formal analysis	YES
2569905	18793439	LS	2	data analysis and writing	data analysis and writing	Analyzed the data|Wrote the paper	Formal analysis	YES
1847704	17440618	AB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1847704	17440618	AB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1847704	17440618	AB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1847704	17440618	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1847704	17440618	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1847704	17440618	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1847704	17440618	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6388008	30967040	A.G.H.	2	conceived the research that led to this discussion paper and wrote the first version of the manuscript	conceived the research that led to this discussion paper and wrote the first version of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
6388008	30967040	B.C.	2	developed the scaling analysis	developed the scaling analysis	-	-	NO
6388008	30967040	all authors	2	contributed to the content of the manuscript and in revising the manuscript	contributed to the content of the manuscript and in revising the manuscript	Wrote the paper	Writing - Review & Editing	YES
3846598	23987136	BAA	2	were involved in data presentation, interpretation and writing of manuscript	were involved in data presentation, interpretation and writing of manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3846598	23987136	JAA	2	were involved in data presentation, interpretation and writing of manuscript	were involved in data presentation, interpretation and writing of manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3846598	23987136	XJJ	2	carried out fermentations and analyses|were involved in data presentation, interpretation and writing of manuscript	carried out fermentations and analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3846598	23987136	XJJ	2	carried out fermentations and analyses|were involved in data presentation, interpretation and writing of manuscript	were involved in data presentation, interpretation and writing of manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3846598	23987136	ZS	2	were involved in data presentation, interpretation and writing of manuscript	were involved in data presentation, interpretation and writing of manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5530509	28747151	MDC	2	designed the study and edited the manuscript	designed the study and edited the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5530509	28747151	MG	2	conducted the experiments, evaluated the data and wrote the manuscript	conducted the experiments, evaluated the data and wrote the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5530509	28747151	PP	2	contributed the hgap assembly|assisted with the evaluation	contributed the hgap assembly	-	-	NO
5530509	28747151	PP	2	contributed the hgap assembly|assisted with the evaluation	assisted with the evaluation	-	-	NO
5530509	28747151	WV	2	assisted with the evaluation	assisted with the evaluation	-	-	NO
4411156	25915904	IF	PLoS5	Conceived and designed the experiments|Provided intellectual input into the writing of the manuscript|Approved the manuscript for submission	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411156	25915904	IF	PLoS5	Conceived and designed the experiments|Provided intellectual input into the writing of the manuscript|Approved the manuscript for submission	Provided intellectual input into the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
4411156	25915904	IF	PLoS5	Conceived and designed the experiments|Provided intellectual input into the writing of the manuscript|Approved the manuscript for submission	Approved the manuscript for submission	-	-	NO
4411156	25915904	JCT	PLoS5	Conceived and designed the experiments|Performed the experiments|Provided intellectual input into the writing of the manuscript|Approved the manuscript for submission	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411156	25915904	JCT	PLoS5	Conceived and designed the experiments|Performed the experiments|Provided intellectual input into the writing of the manuscript|Approved the manuscript for submission	Performed the experiments	Performed the experiments	Investigation	YES
4411156	25915904	JCT	PLoS5	Conceived and designed the experiments|Performed the experiments|Provided intellectual input into the writing of the manuscript|Approved the manuscript for submission	Provided intellectual input into the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
4411156	25915904	JCT	PLoS5	Conceived and designed the experiments|Performed the experiments|Provided intellectual input into the writing of the manuscript|Approved the manuscript for submission	Approved the manuscript for submission	-	-	NO
4411156	25915904	KMF	PLoS5	Conceived and designed the experiments|Performed the experiments|Provided intellectual input into the writing of the manuscript|Approved the manuscript for submission	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411156	25915904	KMF	PLoS5	Conceived and designed the experiments|Performed the experiments|Provided intellectual input into the writing of the manuscript|Approved the manuscript for submission	Performed the experiments	Performed the experiments	Investigation	YES
4411156	25915904	KMF	PLoS5	Conceived and designed the experiments|Performed the experiments|Provided intellectual input into the writing of the manuscript|Approved the manuscript for submission	Provided intellectual input into the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
4411156	25915904	KMF	PLoS5	Conceived and designed the experiments|Performed the experiments|Provided intellectual input into the writing of the manuscript|Approved the manuscript for submission	Approved the manuscript for submission	-	-	NO
4411156	25915904	LF	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Approved the manuscript for submission	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411156	25915904	LF	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Approved the manuscript for submission	Performed the experiments	Performed the experiments	Investigation	YES
4411156	25915904	LF	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Approved the manuscript for submission	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411156	25915904	LF	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Approved the manuscript for submission	Approved the manuscript for submission	-	-	NO
4411156	25915904	MT	PLoS5	Conceived and designed the experiments|Performed the experiments|Provided intellectual input into the writing of the manuscript|Approved the manuscript for submission	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411156	25915904	MT	PLoS5	Conceived and designed the experiments|Performed the experiments|Provided intellectual input into the writing of the manuscript|Approved the manuscript for submission	Performed the experiments	Performed the experiments	Investigation	YES
4411156	25915904	MT	PLoS5	Conceived and designed the experiments|Performed the experiments|Provided intellectual input into the writing of the manuscript|Approved the manuscript for submission	Provided intellectual input into the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
4411156	25915904	MT	PLoS5	Conceived and designed the experiments|Performed the experiments|Provided intellectual input into the writing of the manuscript|Approved the manuscript for submission	Approved the manuscript for submission	-	-	NO
4411156	25915904	NG	PLoS5	Conceived and designed the experiments|Analyzed the data|Provided intellectual input into the writing of the manuscript|Approved the manuscript for submission	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411156	25915904	NG	PLoS5	Conceived and designed the experiments|Analyzed the data|Provided intellectual input into the writing of the manuscript|Approved the manuscript for submission	Analyzed the data	Analyzed the data	Formal analysis	YES
4411156	25915904	NG	PLoS5	Conceived and designed the experiments|Analyzed the data|Provided intellectual input into the writing of the manuscript|Approved the manuscript for submission	Provided intellectual input into the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
4411156	25915904	NG	PLoS5	Conceived and designed the experiments|Analyzed the data|Provided intellectual input into the writing of the manuscript|Approved the manuscript for submission	Approved the manuscript for submission	-	-	NO
4411156	25915904	PGS	PLoS5	Conceived and designed the experiments|Performed the experiments|Provided intellectual input into the writing of the manuscript|Approved the manuscript for submission	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411156	25915904	PGS	PLoS5	Conceived and designed the experiments|Performed the experiments|Provided intellectual input into the writing of the manuscript|Approved the manuscript for submission	Performed the experiments	Performed the experiments	Investigation	YES
4411156	25915904	PGS	PLoS5	Conceived and designed the experiments|Performed the experiments|Provided intellectual input into the writing of the manuscript|Approved the manuscript for submission	Provided intellectual input into the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
4411156	25915904	PGS	PLoS5	Conceived and designed the experiments|Performed the experiments|Provided intellectual input into the writing of the manuscript|Approved the manuscript for submission	Approved the manuscript for submission	-	-	NO
4411156	25915904	RF	PLoS5	Conceived and designed the experiments|Performed the experiments|Provided intellectual input into the writing of the manuscript|Approved the manuscript for submission	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411156	25915904	RF	PLoS5	Conceived and designed the experiments|Performed the experiments|Provided intellectual input into the writing of the manuscript|Approved the manuscript for submission	Performed the experiments	Performed the experiments	Investigation	YES
4411156	25915904	RF	PLoS5	Conceived and designed the experiments|Performed the experiments|Provided intellectual input into the writing of the manuscript|Approved the manuscript for submission	Provided intellectual input into the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
4411156	25915904	RF	PLoS5	Conceived and designed the experiments|Performed the experiments|Provided intellectual input into the writing of the manuscript|Approved the manuscript for submission	Approved the manuscript for submission	-	-	NO
4573615	26425554	Yi Cai	2	contributed equally to this work	contributed equally to this work	-	-	NO
4573615	26425554	Yushi Zhang	2	contributed equally to this work	contributed equally to this work	-	-	NO
5681583	29163612	AT	PLoS5	Conceived and designed the study|Analyzed the data|Wrote the paper	Conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5681583	29163612	AT	PLoS5	Conceived and designed the study|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5681583	29163612	AT	PLoS5	Conceived and designed the study|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5681583	29163612	CX	PLoS5	Performed the evaluation under field conditions	Performed the evaluation under field conditions	Performed the experiments	Investigation	YES
5681583	29163612	JM	PLoS5	Conceived and designed the study|Performed the evaluation under field conditions|Performed the evaluations in controlled conditions|Analyzed the data|Wrote the paper	Conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5681583	29163612	JM	PLoS5	Conceived and designed the study|Performed the evaluation under field conditions|Performed the evaluations in controlled conditions|Analyzed the data|Wrote the paper	Performed the evaluation under field conditions	Performed the experiments	Investigation	YES
5681583	29163612	JM	PLoS5	Conceived and designed the study|Performed the evaluation under field conditions|Performed the evaluations in controlled conditions|Analyzed the data|Wrote the paper	Performed the evaluations in controlled conditions	Performed the experiments	Investigation	YES
5681583	29163612	JM	PLoS5	Conceived and designed the study|Performed the evaluation under field conditions|Performed the evaluations in controlled conditions|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5681583	29163612	JM	PLoS5	Conceived and designed the study|Performed the evaluation under field conditions|Performed the evaluations in controlled conditions|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5681583	29163612	JRV	PLoS5	Performed the evaluation under field conditions	Performed the evaluation under field conditions	Performed the experiments	Investigation	YES
5681583	29163612	LFR	PLoS5	Performed the evaluation under field conditions	Performed the evaluation under field conditions	Performed the experiments	Investigation	YES
5056924	27726115	FI	2	performed and analyzed the pet studies	performed and analyzed the pet studies	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5056924	27726115	RF	2	performed and analyzed the pet studies	performed and analyzed the pet studies	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5056924	27726115	SDV	2	conceived and designed the study|drafted the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5056924	27726115	SDV	2	conceived and designed the study|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5056924	27726115	VDR	2	conceived and designed the study|performed and analyzed the pet studies|drafted the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5056924	27726115	VDR	2	conceived and designed the study|performed and analyzed the pet studies|drafted the manuscript	performed and analyzed the pet studies	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5056924	27726115	VDR	2	conceived and designed the study|performed and analyzed the pet studies|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
2570654	18826587	LK	2	played an important role in study design, data collection, data analysis, statistical analysis and interpretation and manuscript preparation	played an important role in study design, data collection, data analysis, statistical analysis and interpretation and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
2570654	18826587	MH	2	was the primary author of the manuscript and participated in the design of the study and carried out the data collection, data analysis, statistical analysis and interpretation of the results	was the primary author of the manuscript and participated in the design of the study and carried out the data collection, data analysis, statistical analysis and interpretation of the results	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
2570654	18826587	YP	2	played an important role in study design, data collection, data interpretation and study coordination	played an important role in study design, data collection, data interpretation and study coordination	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology|Project administration	YES
6388009	30967034	All authors	2	contributed to the writing of the manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
6388009	30967034	M.V.	2	performed much of the research and implemented the code described herein	performed much of the research and implemented the code described herein	Performed the experiments	Investigation	YES
6388009	30967034	P.V.C.	2	initiated the project and supervised the research	initiated the project and supervised the research	Conceived and designed the experiments	Conceptualization|Supervision	YES
6388009	30967034	R.R.	2	provided assistance with theory and model development, and contributed to the optimized hmm code	provided assistance with theory and model development, and contributed to the optimized hmm code	Performed the experiments|Contributed reagents/materials/analysis tools	Methodology|Software	YES
5537994	28760136	ML	2	participated in the data analysis	participated in the data analysis	Analyzed the data	Formal analysis	YES
5537994	28760136	SW	2	participated in the data analysis	participated in the data analysis	Analyzed the data	Formal analysis	YES
5537994	28760136	YY	2	constructed the f2 population	constructed the f2 population	Performed the experiments	Investigation	YES
5537994	28760136	ZC	2	carried out the phenotyping and genotyping of the f2 progeny	carried out the phenotyping and genotyping of the f2 progeny	Performed the experiments	Investigation	YES
5537994	28760136	ZP	2	participated in the language editing	participated in the language editing	Wrote the paper	Writing - Review & Editing	YES
5537994	28760136	ZY	2	designed the experiments and drafted the manuscript|carried out the phenotyping and genotyping of the f2 progeny	designed the experiments and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5537994	28760136	ZY	2	designed the experiments and drafted the manuscript|carried out the phenotyping and genotyping of the f2 progeny	carried out the phenotyping and genotyping of the f2 progeny	Performed the experiments	Investigation	YES
1847705	17440610	BR	PLoS5	Bred the mice and provided litters	Bred the mice and provided litters	-	-	NO
1847705	17440610	CD	PLoS5	Took in charge the est sequencing project	Took in charge the est sequencing project	Performed the experiments	Investigation	YES
1847705	17440610	CL	PLoS5	Provided technical help in molecular biology and histology	Provided technical help in molecular biology and histology	Performed the experiments	Investigation	YES
1847705	17440610	DN	PLoS5	Provided technical help in molecular biology and histology	Provided technical help in molecular biology and histology	Performed the experiments	Investigation	YES
1847705	17440610	DS	PLoS5	Carried out injections into xenopus embryos	Carried out injections into xenopus embryos	Performed the experiments	Investigation	YES
1847705	17440610	JP	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1847705	17440610	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1847705	17440610	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1847705	17440610	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1847705	17440610	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1847705	17440610	PW	PLoS5	Took in charge the est sequencing project	Took in charge the est sequencing project	Performed the experiments	Investigation	YES
1847705	17440610	SM	PLoS5	Analyzed the data|Wrote the paper|Conducted the work	Analyzed the data	Analyzed the data	Formal analysis	YES
1847705	17440610	SM	PLoS5	Analyzed the data|Wrote the paper|Conducted the work	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1847705	17440610	SM	PLoS5	Analyzed the data|Wrote the paper|Conducted the work	Conducted the work	Performed the experiments	Investigation	YES
1847705	17440610	TS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1847705	17440610	TS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1847705	17440610	TS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1847705	17440610	YL	PLoS5	Bred the mice and provided litters	Bred the mice and provided litters	-	-	NO
3847078	24004544	HPH	2	supervised experimental design and revised the manuscript for submission	supervised experimental design and revised the manuscript for submission	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Review & Editing	YES
3847078	24004544	MK	2	conceived and conducted the conception and design of the study and drafted the manuscript	conceived and conducted the conception and design of the study and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Writing - Original Draft	YES
3847078	24004544	MerE	2	supervised experimental design	supervised experimental design	Conceived and designed the experiments	Methodology|Supervision	YES
3847078	24004544	RN	2	contributed valuable suggestions to the study	contributed valuable suggestions to the study	-	-	NO
3847078	24004544	TI	2	supervised experimental design and revised the manuscript for submission	supervised experimental design and revised the manuscript for submission	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Review & Editing	YES
3847078	24004544	YS	2	carried out the molecular studies, characterized transgenic plants, participated in analysis of mercury accumulation and resistant, and helped to prepare the manuscript	carried out the molecular studies, characterized transgenic plants, participated in analysis of mercury accumulation and resistant, and helped to prepare the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4411157	25915933	BZ	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411157	25915933	GL	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411157	25915933	HW	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411157	25915933	HW	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411157	25915933	HW	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411157	25915933	SM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411157	25915933	TM	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4411157	25915933	TS	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4411157	25915933	XL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411157	25915933	XL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411157	25915933	XL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411157	25915933	YB	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4158265	25210519	Miyako Nishimoto	2	carried out immunolocalization studies and cell spreading analysis and imaging, protein binding studies, and participated in cell attachment studies	carried out immunolocalization studies and cell spreading analysis and imaging, protein binding studies, and participated in cell attachment studies	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
4158265	25210519	Satoru Ken Nishimoto	2	conceived and designed the study and participated in its execution	conceived and designed the study and participated in its execution	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
4573618	26425553	Fang Wang	2	contributed to the design of the study|designed and performed the computational modeling and drafted the paper	contributed to the design of the study	Conceived and designed the experiments	Methodology	YES
4573618	26425553	Fang Wang	2	contributed to the design of the study|designed and performed the computational modeling and drafted the paper	designed and performed the computational modeling and drafted the paper	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4573618	26425553	Guohua Wang	2	contributed to the design of the study|designed and performed the computational modeling and drafted the paper	contributed to the design of the study	Conceived and designed the experiments	Methodology	YES
4573618	26425553	Guohua Wang	2	contributed to the design of the study|designed and performed the computational modeling and drafted the paper	designed and performed the computational modeling and drafted the paper	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4573618	26425553	Qian Huang	2	participated in coordination, discussions related to result interpretation, and revision of the paper	participated in coordination, discussions related to result interpretation, and revision of the paper	Analyzed the data|Wrote the paper	Formal analysis|Project administration|Writing - Review & Editing	YES
4573618	26425553	Yadong Wang	2	contributed to the design of the study|participated in coordination, discussions related to result interpretation, and revision of the paper	contributed to the design of the study	Conceived and designed the experiments	Methodology	YES
4573618	26425553	Yadong Wang	2	contributed to the design of the study|participated in coordination, discussions related to result interpretation, and revision of the paper	participated in coordination, discussions related to result interpretation, and revision of the paper	Analyzed the data|Wrote the paper	Formal analysis|Project administration|Writing - Review & Editing	YES
4573618	26425553	Yu Li	2	designed and performed the computational modeling and drafted the paper|participated in coordination, discussions related to result interpretation, and revision of the paper	designed and performed the computational modeling and drafted the paper	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4573618	26425553	Yu Li	2	designed and performed the computational modeling and drafted the paper|participated in coordination, discussions related to result interpretation, and revision of the paper	participated in coordination, discussions related to result interpretation, and revision of the paper	Analyzed the data|Wrote the paper	Formal analysis|Project administration|Writing - Review & Editing	YES
5681748	29163609	CN	1	Critical discussion of the data	Critical discussion of the data	-	-	NO
5681748	29163609	FV	1	Designing and performing the experiments|Critical discussion of the data	Designing and performing the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5681748	29163609	FV	1	Designing and performing the experiments|Critical discussion of the data	Critical discussion of the data	-	-	NO
5681748	29163609	LL	1	Data analyses|Critical discussion of the data	Data analyses	Analyzed the data	Formal analysis	YES
5681748	29163609	LL	1	Data analyses|Critical discussion of the data	Critical discussion of the data	-	-	NO
5681748	29163609	MS	1	Critical discussion of the data	Critical discussion of the data	-	-	NO
5681748	29163609	PS	1	Critical discussion of the data	Critical discussion of the data	-	-	NO
5681748	29163609	RT	1	Designing and performing the experiments|Data analyses|Critical discussion of the data	Designing and performing the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5681748	29163609	RT	1	Designing and performing the experiments|Data analyses|Critical discussion of the data	Data analyses	Analyzed the data	Formal analysis	YES
5681748	29163609	RT	1	Designing and performing the experiments|Data analyses|Critical discussion of the data	Critical discussion of the data	-	-	NO
5681748	29163609	SC	1	Designing and performing the experiments|Critical discussion of the data|Paper preparation|Research coordination	Designing and performing the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5681748	29163609	SC	1	Designing and performing the experiments|Critical discussion of the data|Paper preparation|Research coordination	Critical discussion of the data	-	-	NO
5681748	29163609	SC	1	Designing and performing the experiments|Critical discussion of the data|Paper preparation|Research coordination	Paper preparation	-	-	NO
5681748	29163609	SC	1	Designing and performing the experiments|Critical discussion of the data|Paper preparation|Research coordination	Research coordination	-	Project administration	YES
5681748	29163609	TM	1	Designing and performing the experiments|Data analyses|Critical discussion of the data|Paper preparation|Research coordination	Designing and performing the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5681748	29163609	TM	1	Designing and performing the experiments|Data analyses|Critical discussion of the data|Paper preparation|Research coordination	Data analyses	Analyzed the data	Formal analysis	YES
5681748	29163609	TM	1	Designing and performing the experiments|Data analyses|Critical discussion of the data|Paper preparation|Research coordination	Critical discussion of the data	-	-	NO
5681748	29163609	TM	1	Designing and performing the experiments|Data analyses|Critical discussion of the data|Paper preparation|Research coordination	Paper preparation	-	-	NO
5681748	29163609	TM	1	Designing and performing the experiments|Data analyses|Critical discussion of the data|Paper preparation|Research coordination	Research coordination	-	Project administration	YES
5681748	29163609	YP	1	Data analyses|Critical discussion of the data|Paper preparation	Data analyses	Analyzed the data	Formal analysis	YES
5681748	29163609	YP	1	Data analyses|Critical discussion of the data|Paper preparation	Critical discussion of the data	-	-	NO
5681748	29163609	YP	1	Data analyses|Critical discussion of the data|Paper preparation	Paper preparation	-	-	NO
5069228	27757932	All authors	2	participated in the design of the study	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
5069228	27757932	ES	2	performed the pet scans|analyzed the images and performed the statistical analysis|drafted the manuscript	performed the pet scans	Performed the experiments	Investigation	YES
5069228	27757932	ES	2	performed the pet scans|analyzed the images and performed the statistical analysis|drafted the manuscript	analyzed the images and performed the statistical analysis	Analyzed the data	Formal analysis|Visualization	YES
5069228	27757932	ES	2	performed the pet scans|analyzed the images and performed the statistical analysis|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5069228	27757932	GH	2	performed the pet scans	performed the pet scans	Performed the experiments	Investigation	YES
5069228	27757932	HK	2	analyzed the images and performed the statistical analysis	analyzed the images and performed the statistical analysis	Analyzed the data	Formal analysis|Visualization	YES
5069228	27757932	IM	2	performed the pet scans	performed the pet scans	Performed the experiments	Investigation	YES
5069228	27757932	JH	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5069228	27757932	KI	2	performed the pet scans|analyzed the images and performed the statistical analysis|drafted the manuscript	performed the pet scans	Performed the experiments	Investigation	YES
5069228	27757932	KI	2	performed the pet scans|analyzed the images and performed the statistical analysis|drafted the manuscript	analyzed the images and performed the statistical analysis	Analyzed the data	Formal analysis|Visualization	YES
5069228	27757932	KI	2	performed the pet scans|analyzed the images and performed the statistical analysis|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5069228	27757932	KM	2	performed the pet scans	performed the pet scans	Performed the experiments	Investigation	YES
5069228	27757932	MT	2	analyzed the images and performed the statistical analysis	analyzed the images and performed the statistical analysis	Analyzed the data	Formal analysis|Visualization	YES
5069228	27757932	SN	2	performed the pet scans	performed the pet scans	Performed the experiments	Investigation	YES
5069228	27757932	TW	2	analyzed the images and performed the statistical analysis	analyzed the images and performed the statistical analysis	Analyzed the data	Formal analysis|Visualization	YES
5069228	27757932	YK	2	performed the pet scans	performed the pet scans	Performed the experiments	Investigation	YES
553965	15717927	A.J.	2	participated in the domain analysis	participated in the domain analysis	-	-	NO
553965	15717927	ArfGEF	2	in plants	in plants	Performed the experiments	Investigation	YES
553965	15717927	B.M.	2	carried out sequence and phylogenetic analysis	carried out sequence and phylogenetic analysis	Performed the experiments	Investigation	YES
553965	15717927	D.S.	2	performed splicing pattern analysis	performed splicing pattern analysis	Performed the experiments	Investigation	YES
553965	15717927	J.Ch	2	conceived and coordinated the study and wrote the manuscript	conceived and coordinated the study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Project administration|Writing - Original Draft	YES
553965	15717927	J.Co	2	annotated paramecium sequences	annotated paramecium sequences	Performed the experiments	Investigation	YES
553965	15717927	P.M.	2	performed splicing pattern analysis	performed splicing pattern analysis	Performed the experiments	Investigation	YES
553965	15717927	V.B.	2	carried out sequence and phylogenetic analysis	carried out sequence and phylogenetic analysis	Performed the experiments	Investigation	YES
2575187	18834505	All authors	2	reviewed content for scientific merit and provided general recommendations in relation to the direction of the manuscript	reviewed content for scientific merit and provided general recommendations in relation to the direction of the manuscript	Wrote the paper	Writing - Review & Editing	YES
2575187	18834505	All co-authors	2	were equally responsible for writing, revising, and providing feedback for submission	were equally responsible for writing, revising, and providing feedback for submission	Wrote the paper	-	YES
1847706	17440611	AA	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1847706	17440611	AA	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1847706	17440611	BD	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1847706	17440611	BD	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1847706	17440611	HG	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1847706	17440611	HG	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1847706	17440611	KH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1847706	17440611	ME	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1847706	17440611	ME	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1847706	17440611	MO	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Analyzed the data|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1847706	17440611	MO	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Analyzed the data|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1847706	17440611	MO	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Analyzed the data|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1847706	17440611	MO	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Analyzed the data|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1847706	17440611	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1847706	17440611	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1847706	17440611	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1847706	17440611	SS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1847706	17440611	SS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1847706	17440611	SS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1847706	17440611	TN	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1847706	17440611	TN	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1847706	17440611	YR	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1847706	17440611	YR	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2579279	18950510	CK	2	was the principal investigator of the study who obtained grant funds for project, designed study, supervised data collection and analysis, supervised statistical analyses, and assisted with manuscript preparation	was the principal investigator of the study who obtained grant funds for project, designed study, supervised data collection and analysis, supervised statistical analyses, and assisted with manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Funding acquisition|Investigation|Methodology|Supervision|Writing - Original Draft	YES
2579279	18950510	JS	2	was the study co-investigator who helped design study and assisted with data collection, statistical analyses, and manuscript preparation	was the study co-investigator who helped design study and assisted with data collection, statistical analyses, and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
2579279	18950510	MR	2	was the primary author, oversaw all aspects of study including recruitment, data/specimen analysis, and manuscript preparation	was the primary author, oversaw all aspects of study including recruitment, data/specimen analysis, and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Supervision|Writing - Original Draft	YES
2579279	18950510	SH	2	was the co-author, assisted with data collection, data analysis and manuscript preparation	was the co-author, assisted with data collection, data analysis and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
2579279	18950510	VD	2	was the co-author, oversaw all aspects of study including recruitment, data/specimen analysis, and manuscript preparation	was the co-author, oversaw all aspects of study including recruitment, data/specimen analysis, and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Supervision|Writing - Original Draft	YES
6388013	30967032	All authors	2	have made contributions to the overall draft such as revisions and critical feedback	have made contributions to the overall draft such as revisions and critical feedback	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6388013	30967032	B.S.	2	has contributed the section on why the kilometre scale matters in global high-resolution simulations	has contributed the section on why the kilometre scale matters in global high-resolution simulations	-	Formal analysis	YES
6388013	30967032	D.K.	2	has contributed to these efforts|have evaluated the dyamond runs	has contributed to these efforts	-	-	NO
6388013	30967032	D.K.	2	has contributed to these efforts|have evaluated the dyamond runs	have evaluated the dyamond runs	-	-	NO
6388013	30967032	ESiWACE	2	demonstrator set-ups and dyamond experiments|further contributed to the development of the performance models	demonstrator set-ups and dyamond experiments	-	-	NO
6388013	30967032	ESiWACE	2	demonstrator set-ups and dyamond experiments|further contributed to the development of the performance models	further contributed to the development of the performance models	Performed the experiments	Investigation|Methodology	YES
6388013	30967032	IFS	2	including scalability experiments and evaluation of energy spectra	including scalability experiments and evaluation of energy spectra	-	-	NO
6388013	30967032	J.B.	2	contributed to the establishment of the performance models|further contributed to the section on scalability challenges	contributed to the establishment of the performance models	Performed the experiments	Investigation|Methodology	YES
6388013	30967032	J.B.	2	contributed to the establishment of the performance models|further contributed to the section on scalability challenges	further contributed to the section on scalability challenges	-	-	NO
6388013	30967032	L.K.	2	has made substantial efforts with regard to setting up, programming and evaluating the icon configuration in global high-resolution mode	has made substantial efforts with regard to setting up, programming and evaluating the icon configuration in global high-resolution mode	Performed the experiments|Contributed reagents/materials/analysis tools	Methodology|Software	YES
6388013	30967032	M.B.	2	have evaluated the dyamond runs	have evaluated the dyamond runs	-	-	NO
6388013	30967032	P.A.	2	contributed to the establishment of the performance models	contributed to the establishment of the performance models	Performed the experiments	Investigation|Methodology	YES
6388013	30967032	P.B.	2	wrote the section on effective versus nominal resolution and made contributions to the ifs global set-up	wrote the section on effective versus nominal resolution and made contributions to the ifs global set-up	Wrote the paper	Writing - Original Draft	YES
6388013	30967032	P.N.	2	has coordinated the writing of the manuscript	has coordinated the writing of the manuscript	Wrote the paper	Project administration|Writing - Original Draft	YES
4411158	25915047	CYZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411158	25915047	CYZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411158	25915047	CYZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411158	25915047	CYZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411158	25915047	CZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411158	25915047	HLY	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411158	25915047	HLY	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411158	25915047	HLY	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411158	25915047	MC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411158	25915047	QLM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411158	25915047	QSG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411158	25915047	QSG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411158	25915047	YL	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5075321	27771904	BS	2	carried out the histopathological evaluation and writing of the manuscript	carried out the histopathological evaluation and writing of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5075321	27771904	CT	2	contributed to the design, recruitment and writing of the manuscript	contributed to the design, recruitment and writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5075321	27771904	HR	2	contributed to the design, recruitment and writing of the manuscript	contributed to the design, recruitment and writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5075321	27771904	IV	2	contributed to the design, recruitment and writing of the manuscript	contributed to the design, recruitment and writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5075321	27771904	JB	2	contributed to the design, recruitment and writing of the manuscript|participated in the radiological review and writing of the manuscript	contributed to the design, recruitment and writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5075321	27771904	JB	2	contributed to the design, recruitment and writing of the manuscript|participated in the radiological review and writing of the manuscript	participated in the radiological review and writing of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5075321	27771904	JP	2	contributed to the design, recruitment and writing of the manuscript	contributed to the design, recruitment and writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5075321	27771904	KN	2	contributed to the design, recruitment and writing of the manuscript	contributed to the design, recruitment and writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5075321	27771904	ML	2	contributed to the design, recruitment and writing of the manuscript	contributed to the design, recruitment and writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5075321	27771904	PT	2	participated in the radiological review and writing of the manuscript	participated in the radiological review and writing of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5075321	27771904	SW	2	contributed to the design, recruitment and writing of the manuscript	contributed to the design, recruitment and writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
553974	15710039	JIP	2	conducted microarray experiments	conducted microarray experiments	Performed the experiments	Investigation	YES
553974	15710039	JMO	2	conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
553974	15710039	WF	2	carried out analyses and prepared the manuscript	carried out analyses and prepared the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5681856	29163557	Q-BZ	2	initiated the study, organized field work, supervised the process of data analysis, and manuscript writing	initiated the study, organized field work, supervised the process of data analysis, and manuscript writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Data curation|Formal analysis|Investigation|Project administration|Supervision|Writing - Original Draft	YES
5681856	29163557	YL	2	conducted the data analysis, and wrote the manuscript	conducted the data analysis, and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
1847707	17440613	CH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1847707	17440613	CH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1847707	17440613	CH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1847707	17440613	LK	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1847707	17440613	LW	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1847707	17440613	MP	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1847707	17440613	MP	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1847707	17440613	MP	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1847707	17440613	PW	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1847707	17440613	SH	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1847707	17440613	SH	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2583972	18831767	AHLJ	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
2583972	18831767	All authors	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
2583972	18831767	BG	2	is the principal investigator of the project|designed the study|collected the data|conducted data analysis	is the principal investigator of the project	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
2583972	18831767	BG	2	is the principal investigator of the project|designed the study|collected the data|conducted data analysis	designed the study	Conceived and designed the experiments	Methodology	YES
2583972	18831767	BG	2	is the principal investigator of the project|designed the study|collected the data|conducted data analysis	collected the data	Performed the experiments	Investigation	YES
2583972	18831767	BG	2	is the principal investigator of the project|designed the study|collected the data|conducted data analysis	conducted data analysis	Analyzed the data	Formal analysis	YES
2583972	18831767	CU	2	collected the data|conducted data analysis	collected the data	Performed the experiments	Investigation	YES
2583972	18831767	CU	2	collected the data|conducted data analysis	conducted data analysis	Analyzed the data	Formal analysis	YES
2583972	18831767	FBB	2	collected the data|conducted data analysis	collected the data	Performed the experiments	Investigation	YES
2583972	18831767	FBB	2	collected the data|conducted data analysis	conducted data analysis	Analyzed the data	Formal analysis	YES
2583972	18831767	FBS	2	collected the data|conducted data analysis	collected the data	Performed the experiments	Investigation	YES
2583972	18831767	FBS	2	collected the data|conducted data analysis	conducted data analysis	Analyzed the data	Formal analysis	YES
2583972	18831767	GGA	2	collected the data|conducted data analysis	collected the data	Performed the experiments	Investigation	YES
2583972	18831767	GGA	2	collected the data|conducted data analysis	conducted data analysis	Analyzed the data	Formal analysis	YES
2583972	18831767	RCH	2	conducted data analysis	conducted data analysis	Analyzed the data	Formal analysis	YES
3851474	24099169	MH	2	carried out the experimental work|interpreted the results|wrote the manuscript	carried out the experimental work	Performed the experiments	Investigation	YES
3851474	24099169	MH	2	carried out the experimental work|interpreted the results|wrote the manuscript	interpreted the results	Analyzed the data	Formal analysis	YES
3851474	24099169	MH	2	carried out the experimental work|interpreted the results|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3851474	24099169	RC	2	designed the experiment|interpreted the results	designed the experiment	Conceived and designed the experiments	Methodology	YES
3851474	24099169	RC	2	designed the experiment|interpreted the results	interpreted the results	Analyzed the data	Formal analysis	YES
3851474	24099169	SRG	2	interpreted the results|wrote the manuscript	interpreted the results	Analyzed the data	Formal analysis	YES
3851474	24099169	SRG	2	interpreted the results|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3851474	24099169	YZ	2	designed the experiment|carried out the experimental work	designed the experiment	Conceived and designed the experiments	Methodology	YES
3851474	24099169	YZ	2	designed the experiment|carried out the experimental work	carried out the experimental work	Performed the experiments	Investigation	YES
4248398	25477962	Ade Kallas	2	was responsible for the conception, design, and execution of experiments, statistical analysis, interpretation of published data, and preparation and editing of this paper	was responsible for the conception, design, and execution of experiments, statistical analysis, interpretation of published data, and preparation and editing of this paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Review & Editing	YES
4248398	25477962	EBs	2	for the experiments	for the experiments	-	-	NO
4248398	25477962	Martin Pook	2	edited the paper	edited the paper	Wrote the paper	Writing - Review & Editing	YES
4248398	25477962	Toivo Maimets	2	edited the paper	edited the paper	Wrote the paper	Writing - Review & Editing	YES
4411159	25915861	DZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411159	25915861	GYY	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4411159	25915861	GYY	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411159	25915861	JCY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411159	25915861	JCY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411159	25915861	JCY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411159	25915861	JCY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411159	25915861	JCY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411159	25915861	JFW	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411159	25915861	JFW	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411159	25915861	WZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411159	25915861	WZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411159	25915861	WZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411159	25915861	WZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411159	25915861	YHZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411159	25915861	YHZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411159	25915861	YHZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411159	25915861	YHZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5540593	28764658	CF	2	performed genome sequencing of the bacterial strains	performed genome sequencing of the bacterial strains	Performed the experiments	Investigation	YES
5540593	28764658	CM	2	performed bioinformatic analyses	performed bioinformatic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5540593	28764658	DVS	2	participated and supervised the study	participated and supervised the study	-	Supervision	YES
5540593	28764658	FT	2	participated and supervised the study	participated and supervised the study	-	Supervision	YES
5540593	28764658	GAL	2	designed the study, performed analyses and wrote the manuscript|performed bioinformatic analyses	designed the study, performed analyses and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5540593	28764658	GAL	2	designed the study, performed analyses and wrote the manuscript|performed bioinformatic analyses	performed bioinformatic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5540593	28764658	KJ	2	provided bacterial strains	provided bacterial strains	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5540593	28764658	LM	2	performed bioinformatic analyses	performed bioinformatic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5540593	28764658	MMa	2	performed genome sequencing of the bacterial strains	performed genome sequencing of the bacterial strains	Performed the experiments	Investigation	YES
5540593	28764658	MMo	2	provided bacterial strains	provided bacterial strains	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5540593	28764658	MV	2	conceived the study, participated in its design and coordination, and contributed to the manuscript preparation	conceived the study, participated in its design and coordination, and contributed to the manuscript preparation	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
5540593	28764658	PM	2	provided bacterial strains	provided bacterial strains	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5540593	28764658	SD	2	performed genome sequencing of the bacterial strains	performed genome sequencing of the bacterial strains	Performed the experiments	Investigation	YES
5078113	27778311	AB	2	performed the experiments and analysed the results	performed the experiments and analysed the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5078113	27778311	EP	2	was responsible for designing the experiments and analysis of the results and wrote the manuscript|were responsible for the design of the study and critically revised the manuscript	was responsible for designing the experiments and analysis of the results and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5078113	27778311	EP	2	was responsible for designing the experiments and analysis of the results and wrote the manuscript|were responsible for the design of the study and critically revised the manuscript	were responsible for the design of the study and critically revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5078113	27778311	JI	2	supported the migration experiments, proliferation studies and result analysis	supported the migration experiments, proliferation studies and result analysis	-	-	NO
5078113	27778311	JW	2	were responsible for the design of the study and critically revised the manuscript	were responsible for the design of the study and critically revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5078113	27778311	LS	2	were responsible for the design of the study and critically revised the manuscript	were responsible for the design of the study and critically revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5078113	27778311	TS	2	performed the experiments and analysed the results	performed the experiments and analysed the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5681926	29163555	JM	2	designed the experiments and wrote the manuscript	designed the experiments and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5681926	29163555	NG	2	designed the experiments, performed the analysis, and wrote the manuscript	designed the experiments, performed the analysis, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
4573627	26425556	Fang Wang	2	performed the experiments and wrote the paper	performed the experiments and wrote the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4573627	26425556	Liran Juan	2	performed the experiments and wrote the paper	performed the experiments and wrote the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4573627	26425556	Yuming Zhao	2	designed the project|revised the paper	designed the project	Conceived and designed the experiments	Methodology	YES
4573627	26425556	Yuming Zhao	2	designed the project|revised the paper	revised the paper	Wrote the paper	Writing - Review & Editing	YES
5681929	29163561	AP	2	assisted with experiments and provided data	assisted with experiments and provided data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5681929	29163561	BS	2	assisted with microscopy and image capturing	assisted with microscopy and image capturing	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
5681929	29163561	HS	2	advised during all stages of the project and co-wrote and edited the manuscript	advised during all stages of the project and co-wrote and edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5681929	29163561	MC	2	assisted with experiments and provided data	assisted with experiments and provided data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5681929	29163561	MM	2	designed and conducted experiments and wrote the manuscript	designed and conducted experiments and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5681929	29163561	SC	2	assisted with experiments and provided data	assisted with experiments and provided data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
1847718	17426818	AH	PLoS5	Conceived and designed the experiments|Performed the experiments|Edited the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1847718	17426818	AH	PLoS5	Conceived and designed the experiments|Performed the experiments|Edited the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
1847718	17426818	AH	PLoS5	Conceived and designed the experiments|Performed the experiments|Edited the manuscript	Edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
1847718	17426818	BP	PLoS5	Analyzed the data|Edited the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
1847718	17426818	BP	PLoS5	Analyzed the data|Edited the manuscript	Edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
1847718	17426818	JA	PLoS5	Conceived and designed the experiments|Edited the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1847718	17426818	JA	PLoS5	Conceived and designed the experiments|Edited the manuscript	Edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
1847718	17426818	JB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1847718	17426818	JB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1847718	17426818	JB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1847718	17426818	KK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1847718	17426818	KK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1847718	17426818	KK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1847718	17426818	KK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1847718	17426818	PN	PLoS5	Performed the experiments|Contributed to experimental design|Edited the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
1847718	17426818	PN	PLoS5	Performed the experiments|Contributed to experimental design|Edited the manuscript	Contributed to experimental design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
1847718	17426818	PN	PLoS5	Performed the experiments|Contributed to experimental design|Edited the manuscript	Edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
554100	15710041	AGSHvR	2	designed the study on comparative genome analysis, performed database searches, sequence alignments and gene structure prediction and drafted the manuscript	designed the study on comparative genome analysis, performed database searches, sequence alignments and gene structure prediction and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Software|Writing - Original Draft	YES
554100	15710041	BvS	2	conducted and analyzed the pcr and sequencing experiments of the exon-intron boundaries of human cortactin and its splice variants	conducted and analyzed the pcr and sequencing experiments of the exon-intron boundaries of human cortactin and its splice variants	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
554100	15710041	ES	2	helped with writing the paper, provided overall technical guidance and coordination	helped with writing the paper, provided overall technical guidance and coordination	Wrote the paper	Project administration|Supervision|Writing - Original Draft	YES
554100	15710041	ESS	2	designed, conducted and analyzed the cloning and sequencing of the promoter of human cortactin	designed, conducted and analyzed the cloning and sequencing of the promoter of human cortactin	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
554100	15710041	PMK	2	read the manuscript and provided comments	read the manuscript and provided comments	-	-	NO
4411160	25915857	AC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411160	25915857	AC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411160	25915857	AC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411160	25915857	AC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411160	25915857	AP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411160	25915857	AP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411160	25915857	AP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411160	25915857	FS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411160	25915857	FS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411160	25915857	FS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411160	25915857	PP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411160	25915857	PP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4411160	25915857	PP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5075677	27826418	DV	2	conceived the study, participated in the design of the study, performed statistical analysis, and drafted the manuscript|carried out experiments|contributed to the writing of the manuscript	conceived the study, participated in the design of the study, performed statistical analysis, and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
5075677	27826418	DV	2	conceived the study, participated in the design of the study, performed statistical analysis, and drafted the manuscript|carried out experiments|contributed to the writing of the manuscript	carried out experiments	Performed the experiments	Investigation	YES
5075677	27826418	DV	2	conceived the study, participated in the design of the study, performed statistical analysis, and drafted the manuscript|carried out experiments|contributed to the writing of the manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5075677	27826418	KN	2	conceived the study, participated in the design of the study, performed statistical analysis, and drafted the manuscript|contributed to the writing of the manuscript	conceived the study, participated in the design of the study, performed statistical analysis, and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
5075677	27826418	KN	2	conceived the study, participated in the design of the study, performed statistical analysis, and drafted the manuscript|contributed to the writing of the manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5075677	27826418	MDM	2	contributed to the writing of the manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5075677	27826418	MNR	2	carried out experiments|contributed to the writing of the manuscript	carried out experiments	Performed the experiments	Investigation	YES
5075677	27826418	MNR	2	carried out experiments|contributed to the writing of the manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5075677	27826418	TRSO	2	contributed to the writing of the manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5075677	27826418	WAS	2	contributed to the writing of the manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5075677	27826418	ZJ	2	contributed to the writing of the manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
1849887	17440615	IR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1849887	17440615	IR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1849887	17440615	IR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1849887	17440615	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1849887	17440615	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1849887	17440615	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1849887	17440615	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1849887	17440615	JR	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1849887	17440615	JR	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1849887	17440615	PP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1849887	17440615	PP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1849887	17440615	PP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1849887	17440615	PP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2585553	18992136	AS	2	assisted in data management, statistical analysis and manuscript preparation	assisted in data management, statistical analysis and manuscript preparation	Analyzed the data|Wrote the paper	Data curation|Formal analysis|Writing - Original Draft	YES
2585553	18992136	BG	2	assisted in study coordination, data management and supervision	assisted in study coordination, data management and supervision	Analyzed the data	Data curation|Project administration|Supervision	YES
2585553	18992136	JC	2	assisted in protocol development and manuscript preparation	assisted in protocol development and manuscript preparation	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
2585553	18992136	JS	2	assisted in study coordination, supervision, protocol development and statistical analysis	assisted in study coordination, supervision, protocol development and statistical analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology|Project administration|Supervision	YES
2585553	18992136	MH	2	assisted in supervision, data management and study coordination	assisted in supervision, data management and study coordination	Analyzed the data	Data curation|Project administration|Supervision	YES
2585553	18992136	RH	2	assisted in protocol development and manuscript preparation	assisted in protocol development and manuscript preparation	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
2585553	18992136	TB	2	assisted in manuscript preparation	assisted in manuscript preparation	Wrote the paper	Writing - Original Draft	YES
5081978	27785766	AB	2	conceived and designed the study|supervised the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5081978	27785766	AB	2	conceived and designed the study|supervised the study	supervised the study	-	Supervision	YES
5081978	27785766	AKB	2	participated in the acquisition of the data|carried out the analysis and interpretation of the data|contributed to the administrative, technical, or material support of the study	participated in the acquisition of the data	Performed the experiments	Investigation	YES
5081978	27785766	AKB	2	participated in the acquisition of the data|carried out the analysis and interpretation of the data|contributed to the administrative, technical, or material support of the study	carried out the analysis and interpretation of the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5081978	27785766	AKB	2	participated in the acquisition of the data|carried out the analysis and interpretation of the data|contributed to the administrative, technical, or material support of the study	contributed to the administrative, technical, or material support of the study	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Project administration|Resources	YES
5081978	27785766	AS	2	contributed to the administrative, technical, or material support of the study	contributed to the administrative, technical, or material support of the study	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Project administration|Resources	YES
5081978	27785766	All authors	2	drafted the manuscript|provided their critical revision of the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5081978	27785766	All authors	2	drafted the manuscript|provided their critical revision of the manuscript	provided their critical revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5081978	27785766	CB	2	conceived and designed the study|participated in the acquisition of the data|carried out the analysis and interpretation of the data	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5081978	27785766	CB	2	conceived and designed the study|participated in the acquisition of the data|carried out the analysis and interpretation of the data	participated in the acquisition of the data	Performed the experiments	Investigation	YES
5081978	27785766	CB	2	conceived and designed the study|participated in the acquisition of the data|carried out the analysis and interpretation of the data	carried out the analysis and interpretation of the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5081978	27785766	CK	2	participated in the acquisition of the data|carried out the analysis and interpretation of the data	participated in the acquisition of the data	Performed the experiments	Investigation	YES
5081978	27785766	CK	2	participated in the acquisition of the data|carried out the analysis and interpretation of the data	carried out the analysis and interpretation of the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5081978	27785766	FL	2	conceived and designed the study|carried out the analysis and interpretation of the data	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5081978	27785766	FL	2	conceived and designed the study|carried out the analysis and interpretation of the data	carried out the analysis and interpretation of the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5081978	27785766	HJW	2	contributed to the administrative, technical, or material support of the study|supervised the study	contributed to the administrative, technical, or material support of the study	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Project administration|Resources	YES
5081978	27785766	HJW	2	contributed to the administrative, technical, or material support of the study|supervised the study	supervised the study	-	Supervision	YES
5081978	27785766	IS	2	carried out the analysis and interpretation of the data	carried out the analysis and interpretation of the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5081978	27785766	KH	2	conceived and designed the study|carried out the analysis and interpretation of the data|supervised the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5081978	27785766	KH	2	conceived and designed the study|carried out the analysis and interpretation of the data|supervised the study	carried out the analysis and interpretation of the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5081978	27785766	KH	2	conceived and designed the study|carried out the analysis and interpretation of the data|supervised the study	supervised the study	-	Supervision	YES
5081978	27785766	TAB	2	participated in the acquisition of the data|carried out the analysis and interpretation of the data|supervised the study	participated in the acquisition of the data	Performed the experiments	Investigation	YES
5081978	27785766	TAB	2	participated in the acquisition of the data|carried out the analysis and interpretation of the data|supervised the study	carried out the analysis and interpretation of the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5081978	27785766	TAB	2	participated in the acquisition of the data|carried out the analysis and interpretation of the data|supervised the study	supervised the study	-	Supervision	YES
6452041	30879414	Both authors	2	contributed equally|have both read and approved the manuscript	contributed equally	-	-	NO
6452041	30879414	Both authors	2	contributed equally|have both read and approved the manuscript	have both read and approved the manuscript	-	-	NO
4411161	25915748	AM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411161	25915748	FB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411161	25915748	FB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411161	25915748	FB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411161	25915748	HK	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411161	25915748	JLM	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4411161	25915748	JLM	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4411161	25915748	MCE	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411161	25915748	MCE	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411161	25915748	MD	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4411161	25915748	MD	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4411161	25915748	OZ	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411161	25915748	TO	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411161	25915748	VRS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411161	25915748	VRS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411161	25915748	VRS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411161	25915748	VRS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411161	25915748	WZ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5681934	29163630	GL	PLoS52	conceived and designed the study|reviewed and edited the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5681934	29163630	GL	PLoS52	conceived and designed the study|reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5681934	29163630	GW	PLoS52	conceived and designed the study|reviewed and edited the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5681934	29163630	GW	PLoS52	conceived and designed the study|reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5681934	29163630	HJ	PLoS52	wrote the paper|reviewed and edited the manuscript	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5681934	29163630	HJ	PLoS52	wrote the paper|reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5681934	29163630	HZ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5681934	29163630	MD	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5681934	29163630	SX	PLoS52	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5075678	27826419	ARM	2	helped develop the diffusion model and edited the manuscript, and designed the original in vitro and in vivo exposures upon which the analysis is based	helped develop the diffusion model and edited the manuscript, and designed the original in vitro and in vivo exposures upon which the analysis is based	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5075678	27826419	GC	2	helped to conceive the study and read the manuscript	helped to conceive the study and read the manuscript	Conceived and designed the experiments	Conceptualization	YES
5075678	27826419	IK	2	conceived the study, analyzed the results and drafted the manuscript	conceived the study, analyzed the results and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
5075678	27826419	JM	2	developed the pharmacokinetics model and read the manuscript	developed the pharmacokinetics model and read the manuscript	Performed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5075678	27826419	MP	2	further developed the pharmacokinetics model, ran the simulations and organized the data, and read the manuscript	further developed the pharmacokinetics model, ran the simulations and organized the data, and read the manuscript	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
1849888	17440619	AM	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1849888	17440619	DR	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1849888	17440619	DR	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1849888	17440619	FC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1849888	17440619	FC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1849888	17440619	FC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1849888	17440619	FC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1849888	17440619	JV	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1849888	17440619	JV	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
554113	15715905	All the authors	2	contributed to interpretation of the data and to writing the final manuscript	contributed to interpretation of the data and to writing the final manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft|Writing - Review & Editing	YES
554113	15715905	DJS	2	conceived the original study, carried out the bioinformatics analyses, and drafted the manuscript	conceived the original study, carried out the bioinformatics analyses, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
554113	15715905	GMP	2	conceived the original study, carried out the bioinformatics analyses, and drafted the manuscript	conceived the original study, carried out the bioinformatics analyses, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
554113	15715905	JAD	2	proposed extending the study to symbionts as well as pathogens	proposed extending the study to symbionts as well as pathogens	Conceived and designed the experiments	Conceptualization	YES
4573875	26425562	Cheng-Di Wang	2	contributed equally to this work	contributed equally to this work	-	-	NO
4573875	26425562	Lin Huang	2	contributed equally to this work	contributed equally to this work	-	-	NO
4573875	26425562	Nan Chen	2	contributed equally to this work	contributed equally to this work	-	-	NO
2585554	18990209	ACL	2	assisted in the study design, the data analysis and interpretation, and in the draft of the final manuscript	assisted in the study design, the data analysis and interpretation, and in the draft of the final manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
2585554	18990209	AVR	2	also assisted in the study design, the data analysis and interpretation, and in the final draft of the manuscript	also assisted in the study design, the data analysis and interpretation, and in the final draft of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
2585554	18990209	JMB	2	participated at the lead author and was responsible for the study design, screening and recruitment, data collection, data analysis and interpretation, and for the final draft of the manuscript	participated at the lead author and was responsible for the study design, screening and recruitment, data collection, data analysis and interpretation, and for the final draft of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5075679	27826420	AM	PLoS52	reviewed the studies in animal models	reviewed the studies in animal models	Performed the experiments	Methodology	YES
5075679	27826420	JHZ	PLoS52	modified the language	modified the language	-	-	NO
5075679	27826420	JT	PLoS52	modified the language	modified the language	-	-	NO
5075679	27826420	NM	PLoS52	reviewed the studies in animal models	reviewed the studies in animal models	Performed the experiments	Methodology	YES
5075679	27826420	QH	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5075679	27826420	TX	PLoS52	reviewed the studies in the clinic	reviewed the studies in the clinic	-	-	NO
5075679	27826420	ZG	PLoS52	reviewed the studies in the clinic	reviewed the studies in the clinic	-	-	NO
5541427	28768481	All authors	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5541427	28768481	BTM	2	performed the analyses described in this manuscript	performed the analyses described in this manuscript	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5541427	28768481	JK	2	performed the analyses described in this manuscript	performed the analyses described in this manuscript	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5541427	28768481	MGG	2	performed the analyses described in this manuscript	performed the analyses described in this manuscript	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5541427	28768481	NZ	2	performed the analyses described in this manuscript	performed the analyses described in this manuscript	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4411162	25915776	GLI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411162	25915776	GLI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411162	25915776	GLI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411162	25915776	GLI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411162	25915776	GLI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411162	25915776	JRB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411162	25915776	JRB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411162	25915776	JRB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411162	25915776	JRB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411162	25915776	JRB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411162	25915776	JRS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411162	25915776	JRS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411162	25915776	JRS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411162	25915776	JRS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411162	25915776	JRS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411162	25915776	MES	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411162	25915776	MES	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411162	25915776	MES	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411162	25915776	MES	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411162	25915776	MES	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411162	25915776	MKSH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411162	25915776	MKSH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411162	25915776	MKSH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411162	25915776	MKSH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411162	25915776	MKSH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411162	25915776	RE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411162	25915776	RE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411162	25915776	RE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411162	25915776	RE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411162	25915776	RE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411162	25915776	RTL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411162	25915776	RTL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411162	25915776	RTL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411162	25915776	RTL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411162	25915776	RTL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411162	25915776	SB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411162	25915776	SB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411162	25915776	SB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411162	25915776	SB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411162	25915776	SB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411162	25915776	WJP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411162	25915776	WJP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411162	25915776	WJP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411162	25915776	WJP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411162	25915776	WJP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1849889	17440606	AP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1849889	17440606	AP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1849889	17440606	AP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1849889	17440606	AP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1849889	17440606	AP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1849889	17440606	FN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1849889	17440606	FN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1849889	17440606	FN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1849889	17440606	FN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1849889	17440606	LN	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1849889	17440606	LN	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1849889	17440606	PS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1849889	17440606	PS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1849889	17440606	PS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1849889	17440606	PS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1849889	17440606	TD	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1849889	17440606	TD	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1849889	17440606	YG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1849889	17440606	YG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1849889	17440606	YG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1849889	17440606	YG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1849889	17440606	YG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6452050	30929636	A.N.	2	did initial analysis during beamtime and reviewed the manuscript	did initial analysis during beamtime and reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
6452050	30929636	J.M.G.	2	designed and carried out the experiment and drafted the manuscript	designed and carried out the experiment and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
6452050	30929636	J.P.C.	2	helped carry out the experiment, provided initial insight for analysis and reviewed the manuscript	helped carry out the experiment, provided initial insight for analysis and reviewed the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
6452050	30929636	M.R.W.	2	carried out the analysis, derived the theory and drafted the manuscript	carried out the analysis, derived the theory and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6452050	30929636	P.H.B.	2	advised the project through experiment and analysis and drafted the manuscript	advised the project through experiment and analysis and drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5541697	28768482	BK	7	designed and coordinated the study, carried out experiments and wrote the manuscript	designed and coordinated the study, carried out experiments and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Project administration|Writing - Original Draft	YES
5541697	28768482	CC	7	provided scientific data interpretation and wrote the manuscript	provided scientific data interpretation and wrote the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
5541697	28768482	JH	7	performed snp analyses and wrote the manuscript	performed snp analyses and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5541697	28768482	NH	7	performed snp analyses and wrote the manuscript	performed snp analyses and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5541697	28768482	RC	7	provided scientific data interpretation and wrote the manuscript	provided scientific data interpretation and wrote the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
5541697	28768482	SF	7	designed and coordinated the study, carried out experiments and wrote the manuscript	designed and coordinated the study, carried out experiments and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Project administration|Writing - Original Draft	YES
5541697	28768482	SY	7	performed snp analyses and wrote the manuscript	performed snp analyses and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5541697	28768482	SZ	7	designed and coordinated the study, carried out experiments and wrote the manuscript	designed and coordinated the study, carried out experiments and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Project administration|Writing - Original Draft	YES
3896689	24373204	DW	2	designed strains	designed strains	Conceived and designed the experiments|Performed the experiments	Investigation	YES
3896689	24373204	HS	2	designed strains	designed strains	Conceived and designed the experiments|Performed the experiments	Investigation	YES
3896689	24373204	HT	2	commented and supervised on the manuscript	commented and supervised on the manuscript	-	Supervision	YES
3896689	24373204	IT	2	performed strain construction and fermentation assay	performed strain construction and fermentation assay	Performed the experiments	Investigation	YES
3896689	24373204	JO	2	commented and supervised on the manuscript	commented and supervised on the manuscript	-	Supervision	YES
3896689	24373204	JS	2	designed research and wrote the manuscript	designed research and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3896689	24373204	KT	2	designed strains	designed strains	Conceived and designed the experiments|Performed the experiments	Investigation	YES
3896689	24373204	YY	2	performed strain construction and fermentation assay	performed strain construction and fermentation assay	Performed the experiments	Investigation	YES
5101239	27826950	BCL	2	all contributed to the synthesis of the flumazenil precursor and with expertise in radiochemistry, as well as revising the manuscript	all contributed to the synthesis of the flumazenil precursor and with expertise in radiochemistry, as well as revising the manuscript	Wrote the paper	Writing - Review & Editing	YES
5101239	27826950	Each author	2	contributed significantly to the submitted work	contributed significantly to the submitted work	-	-	NO
5101239	27826950	FZ	2	contributed with the quantitative data analysis	contributed with the quantitative data analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5101239	27826950	JHJ	2	all contributed to the synthesis of the flumazenil precursor and with expertise in radiochemistry, as well as revising the manuscript	all contributed to the synthesis of the flumazenil precursor and with expertise in radiochemistry, as well as revising the manuscript	Wrote the paper	Writing - Review & Editing	YES
5101239	27826950	JHP	2	was in charge of the radiochemistry and radiochemical analysis	was in charge of the radiochemistry and radiochemical analysis	Performed the experiments	Investigation	YES
5101239	27826950	LF	2	contributed with expertise in human anesthetics and expert knowledge of the gaba a receptor system in humans, as well as interpretation of the data	contributed with expertise in human anesthetics and expert knowledge of the gaba a receptor system in humans, as well as interpretation of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5101239	27826950	MP	2	was in charge of the study, designing the study, acquiring the data, analyzing and interpreting the results, producing figures and images and writing of the manuscript	was in charge of the study, designing the study, acquiring the data, analyzing and interpreting the results, producing figures and images and writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Visualization|Writing - Original Draft	YES
5101239	27826950	PET	2	image analysis|imaging, as well as interpretation of the data and writing of the manuscript	image analysis	Analyzed the data	Visualization	YES
5101239	27826950	PET	2	image analysis|imaging, as well as interpretation of the data and writing of the manuscript	imaging, as well as interpretation of the data and writing of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Visualization|Writing - Original Draft	YES
5101239	27826950	SB	2	contributed to the animal experiments	contributed to the animal experiments	Performed the experiments	Investigation	YES
5101239	27826950	SEK	2	all contributed to the synthesis of the flumazenil precursor and with expertise in radiochemistry, as well as revising the manuscript	all contributed to the synthesis of the flumazenil precursor and with expertise in radiochemistry, as well as revising the manuscript	Wrote the paper	Writing - Review & Editing	YES
5681945	29163629	GB	2	conceived and designed the experiments and wrote the paper|performed the experiments and analyzed the data	conceived and designed the experiments and wrote the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
5681945	29163629	GB	2	conceived and designed the experiments and wrote the paper|performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5681945	29163629	US	2	conceived and designed the experiments and wrote the paper	conceived and designed the experiments and wrote the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
2621121	19126212	ADF	2	were co-authors, oversaw all aspects of study including recruitment, data/specimen analysis, and manuscript preparation	were co-authors, oversaw all aspects of study including recruitment, data/specimen analysis, and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Supervision|Writing - Original Draft	YES
2621121	19126212	CPT	2	were co-authors, assisting with data collection and data analysis	were co-authors, assisting with data collection and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
2621121	19126212	JK	2	were co-authors, oversaw all aspects of study including recruitment, data/specimen analysis, and manuscript preparation	were co-authors, oversaw all aspects of study including recruitment, data/specimen analysis, and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Supervision|Writing - Original Draft	YES
2621121	19126212	JRH	2	was the primary investigator, obtained grant funds for project, designed study, supervised all study recruitment, data/specimen analysis, statistical analysis and manuscript preparation	was the primary investigator, obtained grant funds for project, designed study, supervised all study recruitment, data/specimen analysis, statistical analysis and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Funding acquisition|Investigation|Methodology|Supervision|Writing - Original Draft	YES
2621121	19126212	NAR	2	were co-authors, oversaw all aspects of study including recruitment, data/specimen analysis, and manuscript preparation	were co-authors, oversaw all aspects of study including recruitment, data/specimen analysis, and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Supervision|Writing - Original Draft	YES
2621121	19126212	SCR	2	were co-authors, assisting with data collection and data analysis	were co-authors, assisting with data collection and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4411163	25915399	HA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411163	25915399	HA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411163	25915399	HA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411163	25915399	ID	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411163	25915399	ID	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411163	25915399	ID	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411163	25915399	ID	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411163	25915399	ID	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1849890	17440620	HK	PLoS5	Analyzed the data|Wrote the paper|Developed the initial theory and developed the simulations	Analyzed the data	Analyzed the data	Formal analysis	YES
1849890	17440620	HK	PLoS5	Analyzed the data|Wrote the paper|Developed the initial theory and developed the simulations	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1849890	17440620	HK	PLoS5	Analyzed the data|Wrote the paper|Developed the initial theory and developed the simulations	Developed the initial theory and developed the simulations	-	Formal analysis	YES
1849890	17440620	NN	PLoS5	Analyzed the data|Developed the fortran programs	Analyzed the data	Analyzed the data	Formal analysis	YES
1849890	17440620	NN	PLoS5	Analyzed the data|Developed the fortran programs	Developed the fortran programs	-	Software	YES
1849890	17440620	PW	PLoS5	Wrote the paper|Developed the simulations, added biological/theoretical interpretations and revised the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1849890	17440620	PW	PLoS5	Wrote the paper|Developed the simulations, added biological/theoretical interpretations and revised the manuscript	Developed the simulations, added biological/theoretical interpretations and revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
1849890	17440620	TO	PLoS5	Analyzed the data|Developed the fortran programs	Analyzed the data	Analyzed the data	Formal analysis	YES
1849890	17440620	TO	PLoS5	Analyzed the data|Developed the fortran programs	Developed the fortran programs	-	Software	YES
1849890	17440620	TW	PLoS5	Analyzed the data|Developed the fortran programs	Analyzed the data	Analyzed the data	Formal analysis	YES
1849890	17440620	TW	PLoS5	Analyzed the data|Developed the fortran programs	Developed the fortran programs	-	Software	YES
1849890	17440620	YK	PLoS5	Analyzed the data|Wrote the paper|Developed the initial theory and developed the simulations	Analyzed the data	Analyzed the data	Formal analysis	YES
1849890	17440620	YK	PLoS5	Analyzed the data|Wrote the paper|Developed the initial theory and developed the simulations	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1849890	17440620	YK	PLoS5	Analyzed the data|Wrote the paper|Developed the initial theory and developed the simulations	Developed the initial theory and developed the simulations	-	Formal analysis	YES
1849890	17440620	YO	PLoS5	Analyzed the data|Developed the fortran programs	Analyzed the data	Analyzed the data	Formal analysis	YES
1849890	17440620	YO	PLoS5	Analyzed the data|Developed the fortran programs	Developed the fortran programs	-	Software	YES
5075680	27826417	AH	2	helped to perform the study and draft the manuscript	helped to perform the study and draft the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5075680	27826417	JL	2	helped to perform the study and draft the manuscript	helped to perform the study and draft the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5075680	27826417	LG	2	helped to perform the study and draft the manuscript	helped to perform the study and draft the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5075680	27826417	MC	2	conceived the study, participated in the study design and coordination and helped to draft the manuscript	conceived the study, participated in the study design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
5075680	27826417	MK	2	conducted the laboratory work, performed the statistical analysis and drafted the manuscript	conducted the laboratory work, performed the statistical analysis and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5075680	27826417	RR	2	participated in the study design and coordination and helped to draft the manuscript	participated in the study design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft	YES
5541722	28768484	BT	2	designed the studies described in this study, and wrote the manuscript	designed the studies described in this study, and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5541722	28768484	CDJ	2	contributed to the rna seq analysis and revised manuscript	contributed to the rna seq analysis and revised manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5541722	28768484	GT	2	participated in experimental design, and edited the manuscript with valuable advice on data analysis and chart display	participated in experimental design, and edited the manuscript with valuable advice on data analysis and chart display	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Review & Editing	YES
5541722	28768484	HNT	2	designed the studies described in this study, and wrote the manuscript	designed the studies described in this study, and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5541722	28768484	SCN	2	bioassays, rna seq experiments with data analyses, and the real time pcr with data analyses	bioassays, rna seq experiments with data analyses, and the real time pcr with data analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5541722	28768484	SW	2	contributed to the rna seq analysis and revised manuscript	contributed to the rna seq analysis and revised manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5541722	28768484	TCT	2	participated in data analysis and revised manuscript	participated in data analysis and revised manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4411164	25915934	BG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411164	25915934	BG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411164	25915934	BG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411164	25915934	JE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411164	25915934	JE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411164	25915934	JE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411164	25915934	JE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5112222	27854031	AA	2	contributed to the design, conduct and manuscript preparation	contributed to the design, conduct and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5112222	27854031	AC	2	contributed to the analysis and manuscript preparation	contributed to the analysis and manuscript preparation	Wrote the paper	Writing - Original Draft	YES
5112222	27854031	DP	2	contributed to the manuscript preparation	contributed to the manuscript preparation	Wrote the paper	Writing - Original Draft	YES
5112222	27854031	EOA	2	contributed to the design, analysis and manuscript preparation	contributed to the design, analysis and manuscript preparation	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
5112222	27854031	GH	2	contributed to the design and manuscript preparation	contributed to the design and manuscript preparation	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
5112222	27854031	PM	2	contributed to the analysis and manuscript preparation	contributed to the analysis and manuscript preparation	Wrote the paper	Writing - Original Draft	YES
5112222	27854031	RG	2	contributed to the manuscript preparation	contributed to the manuscript preparation	Wrote the paper	Writing - Original Draft	YES
5112222	27854031	RR	2	contributed to the statistical methodology and manuscript preparation	contributed to the statistical methodology and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5112222	27854031	RS	2	contributed to the design, analysis and manuscript preparation and submission	contributed to the design, analysis and manuscript preparation and submission	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
5112222	27854031	SM	2	contributed to the manuscript preparation	contributed to the manuscript preparation	Wrote the paper	Writing - Original Draft	YES
5112222	27854031	TB	2	contributed to the analysis and manuscript preparation	contributed to the analysis and manuscript preparation	Wrote the paper	Writing - Original Draft	YES
2621122	19126213	ADF	2	were co-authors, oversaw all aspects of study including recruitment, data/specimen analysis, and manuscript preparation	were co-authors, oversaw all aspects of study including recruitment, data/specimen analysis, and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Supervision|Writing - Original Draft	YES
2621122	19126213	CPT	2	were co-authors, assisting with data collection and data analysis	were co-authors, assisting with data collection and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
2621122	19126213	JK	2	were co-authors, oversaw all aspects of study including recruitment, data/specimen analysis, and manuscript preparation	were co-authors, oversaw all aspects of study including recruitment, data/specimen analysis, and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Supervision|Writing - Original Draft	YES
2621122	19126213	JRH	2	was the primary investigator, obtained grant funds for project, designed study, supervised all study recruitment, data/specimen analysis, statistical analysis and manuscript preparation	was the primary investigator, obtained grant funds for project, designed study, supervised all study recruitment, data/specimen analysis, statistical analysis and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Funding acquisition|Investigation|Methodology|Supervision|Writing - Original Draft	YES
2621122	19126213	MWH	2	were co-authors, assisting with data collection and data analysis	were co-authors, assisting with data collection and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
2621122	19126213	NAR	2	were co-authors, oversaw all aspects of study including recruitment, data/specimen analysis, and manuscript preparation	were co-authors, oversaw all aspects of study including recruitment, data/specimen analysis, and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Supervision|Writing - Original Draft	YES
5075681	27826421	XJ	2	obtained the funding	obtained the funding	-	Funding acquisition	YES
5681951	29163560	AS	2	developed mapping populations and looked after the breeding aspect of study	developed mapping populations and looked after the breeding aspect of study	Performed the experiments	Investigation	YES
5681951	29163560	PK	2	supervised the work and contributed in the revision of manuscript	supervised the work and contributed in the revision of manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
5681951	29163560	RS	2	helped in the bioinformatics analysis and revision of the manuscript	helped in the bioinformatics analysis and revision of the manuscript	Wrote the paper	Formal analysis|Writing - Review & Editing	YES
1849891	17440621	AB	PLoS5	Contributed to the experimental work and analysis of data	Contributed to the experimental work and analysis of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
1849891	17440621	AC	PLoS5	Provided assistance with the tap-tagging experiments	Provided assistance with the tap-tagging experiments	Performed the experiments	Investigation	YES
1849891	17440621	CB	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1849891	17440621	CB	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1849891	17440621	DL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1849891	17440621	DL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1849891	17440621	DL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1849891	17440621	DL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1849891	17440621	EL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1849891	17440621	EL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1849891	17440621	EL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1849891	17440621	JC	PLoS5	Contributed to the experimental work and analysis of data	Contributed to the experimental work and analysis of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
1849891	17440621	JW	PLoS5	Contributed to the experimental work and analysis of data	Contributed to the experimental work and analysis of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
1849891	17440621	KE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1849891	17440621	KE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1849891	17440621	KE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1849891	17440621	KE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1849891	17440621	MO	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1849891	17440621	MO	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1849891	17440621	NM	PLoS5	Contributed to the experimental work and analysis of data|Contributed to the writing of the paper	Contributed to the experimental work and analysis of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
1849891	17440621	NM	PLoS5	Contributed to the experimental work and analysis of data|Contributed to the writing of the paper	Contributed to the writing of the paper	Wrote the paper	Writing - Original Draft	YES
1849891	17440621	PW	PLoS5	Provided assistance with the tap-tagging experiments	Provided assistance with the tap-tagging experiments	Performed the experiments	Investigation	YES
1849891	17440621	RA	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1849891	17440621	RA	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1849891	17440621	ST	PLoS5	Contributed to the experimental work and analysis of data	Contributed to the experimental work and analysis of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
1849891	17440621	TK	PLoS5	Contributed to the experimental work and analysis of data	Contributed to the experimental work and analysis of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
4573887	26448948	Douglas M. Dahl	2	contributed equally to the paper	contributed equally to the paper	-	-	NO
4573887	26448948	Jiwei Huang	2	contributed equally to the paper	contributed equally to the paper	-	-	NO
5541746	28768496	JFC	PLoS52	performed the experiments including rna extraction, cdna synthesis, gene expression, and bioinformatics analysis|wrote the paper	performed the experiments including rna extraction, cdna synthesis, gene expression, and bioinformatics analysis	Performed the experiments	Formal analysis|Investigation	YES
5541746	28768496	JFC	PLoS52	performed the experiments including rna extraction, cdna synthesis, gene expression, and bioinformatics analysis|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5541746	28768496	LHZ	PLoS52	conceived and designed the study|wrote the paper	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5541746	28768496	LHZ	PLoS52	conceived and designed the study|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5541746	28768496	WMZ	PLoS52	conceived and designed the study|wrote the paper	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5541746	28768496	WMZ	PLoS52	conceived and designed the study|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5541746	28768496	ZH	PLoS52	worked for fish breeding and sample collecting	worked for fish breeding and sample collecting	Performed the experiments	Investigation	YES
2626573	19108717	EEN	2	also assisted in the study design, screening and recruitment, data collection, data analysis and interpretation, and for the final draft of the manuscript	also assisted in the study design, screening and recruitment, data collection, data analysis and interpretation, and for the final draft of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
2626573	19108717	JMB	2	participated at the lead author and was responsible for the study design, screening and recruitment, data collection, data analysis and interpretation, and for the final draft of the manuscript	participated at the lead author and was responsible for the study design, screening and recruitment, data collection, data analysis and interpretation, and for the final draft of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
2626573	19108717	PWR	2	acting as a thesis advisor and senior author, was responsible for assisting in the study design, data analysis and interpretation, and final draft	acting as a thesis advisor and senior author, was responsible for assisting in the study design, data analysis and interpretation, and final draft	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4411165	25915642	CH	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411165	25915642	CH	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411165	25915642	CH	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411165	25915642	CH	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411165	25915642	FB	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411165	25915642	FB	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411165	25915642	FB	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411165	25915642	JB	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411165	25915642	JB	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411165	25915642	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411165	25915642	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411165	25915642	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411165	25915642	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411165	25915642	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411165	25915642	JRF	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411165	25915642	JRF	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411165	25915642	JRF	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411165	25915642	KS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411165	25915642	KS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411165	25915642	KS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411165	25915642	KS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411165	25915642	KS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411165	25915642	MV	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411165	25915642	MV	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411165	25915642	MV	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411165	25915642	YLM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411165	25915642	YLM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411165	25915642	YLM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411165	25915642	YLM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5118228	27873240	All authors	2	prepared the manuscript and read and approved the final manuscript	prepared the manuscript and read and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5118228	27873240	EB	2	are involved in the study design|performed the experiments and data analysis	are involved in the study design	Conceived and designed the experiments	Methodology	YES
5118228	27873240	EB	2	are involved in the study design|performed the experiments and data analysis	performed the experiments and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5118228	27873240	HSC	2	are involved in the study design|performed the experiments and data analysis	are involved in the study design	Conceived and designed the experiments	Methodology	YES
5118228	27873240	HSC	2	are involved in the study design|performed the experiments and data analysis	performed the experiments and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5118228	27873240	JPN	2	are involved in the study design	are involved in the study design	Conceived and designed the experiments	Methodology	YES
5118228	27873240	MJ	2	are involved in the study design	are involved in the study design	Conceived and designed the experiments	Methodology	YES
5118228	27873240	MM	2	performed the experiments and data analysis	performed the experiments and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5118228	27873240	MN	2	performed the experiments and data analysis	performed the experiments and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5118228	27873240	MWK	2	are involved in the study design|performed the experiments and data analysis	are involved in the study design	Conceived and designed the experiments	Methodology	YES
5118228	27873240	MWK	2	are involved in the study design|performed the experiments and data analysis	performed the experiments and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5118228	27873240	RWA	2	are involved in the study design	are involved in the study design	Conceived and designed the experiments	Methodology	YES
5118228	27873240	TD	2	are involved in the study design|performed the experiments and data analysis	are involved in the study design	Conceived and designed the experiments	Methodology	YES
5118228	27873240	TD	2	are involved in the study design|performed the experiments and data analysis	performed the experiments and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5118228	27873240	WAB	2	are involved in the study design	are involved in the study design	Conceived and designed the experiments	Methodology	YES
1849892	17440622	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1849892	17440622	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1849892	17440622	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1849892	17440622	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1849892	17440622	LT	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1849892	17440622	LT	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1849892	17440622	ML	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1849892	17440622	ML	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1849892	17440622	ML	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1849892	17440622	RC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1849892	17440622	RC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1849892	17440622	RC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1849892	17440622	SS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1849892	17440622	SS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1849892	17440622	SS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5075682	27826422	EM	2	contributed with abstract and revised the manuscript for edits and important intellectual content	contributed with abstract and revised the manuscript for edits and important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5075682	27826422	EP	2	contributed to a global ischemia section	contributed to a global ischemia section	-	-	NO
5075682	27826422	Each author	2	believes that the manuscript represents honest work	believes that the manuscript represents honest work	-	-	NO
4553341	26351455	All authors	2	participated in the conception and experimental design and in the analysis and interpretation of data and revised the paper for important intellectual content before giving final approval	participated in the conception and experimental design and in the analysis and interpretation of data and revised the paper for important intellectual content before giving final approval	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Review & Editing	YES
4553341	26351455	Mauricio Di Fulvio	2	performed mrna expression analyses, conceived the studies, and wrote the paper	performed mrna expression analyses, conceived the studies, and wrote the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
4553341	26351455	Richa Singh	2	carried out protein expression, deglycosylation, and immunolocalization experiments and their densitometry/morphometry analyses and drafted the first version of the paper	carried out protein expression, deglycosylation, and immunolocalization experiments and their densitometry/morphometry analyses and drafted the first version of the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4553341	26351455	Romario Pacheco-Andrade	2	performed antibody characterization experiments	performed antibody characterization experiments	Performed the experiments	Investigation	YES
5681961	29163627	AD	2	involved in field data collection	involved in field data collection	Performed the experiments	Investigation	YES
5681961	29163627	AM	2	commented on the manuscript	commented on the manuscript	-	-	NO
5681961	29163627	FB	2	planned and designed the research|analyzed the data and wrote the manuscript	planned and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5681961	29163627	FB	2	planned and designed the research|analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5681961	29163627	GG-I	2	commented on the manuscript	commented on the manuscript	-	-	NO
5681961	29163627	J-GH	2	planned and designed the research|involved in field data collection|involved in fund raising|commented on the manuscript	planned and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5681961	29163627	J-GH	2	planned and designed the research|involved in field data collection|involved in fund raising|commented on the manuscript	involved in field data collection	Performed the experiments	Investigation	YES
5681961	29163627	J-GH	2	planned and designed the research|involved in field data collection|involved in fund raising|commented on the manuscript	involved in fund raising	-	Funding acquisition	YES
5681961	29163627	J-GH	2	planned and designed the research|involved in field data collection|involved in fund raising|commented on the manuscript	commented on the manuscript	-	-	NO
5681961	29163627	KS	2	involved in fund raising|commented on the manuscript	involved in fund raising	-	Funding acquisition	YES
5681961	29163627	KS	2	involved in fund raising|commented on the manuscript	commented on the manuscript	-	-	NO
5681961	29163627	PC	2	involved in fund raising|commented on the manuscript	involved in fund raising	-	Funding acquisition	YES
5681961	29163627	PC	2	involved in fund raising|commented on the manuscript	commented on the manuscript	-	-	NO
5681961	29163627	SA	2	planned and designed the research|analyzed the data and wrote the manuscript	planned and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5681961	29163627	SA	2	planned and designed the research|analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5681961	29163627	TA	2	commented on the manuscript	commented on the manuscript	-	-	NO
5681961	29163627	TH	2	planned and designed the research|commented on the manuscript	planned and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5681961	29163627	TH	2	planned and designed the research|commented on the manuscript	commented on the manuscript	-	-	NO
5681961	29163627	TV	2	involved in fund raising|commented on the manuscript	involved in fund raising	-	Funding acquisition	YES
5681961	29163627	TV	2	involved in fund raising|commented on the manuscript	commented on the manuscript	-	-	NO
5681961	29163627	The authors	2	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	Performed the experiments	Investigation	YES
5956983	29896389	A.A.	2	contributed in amino linker synthesis	contributed in amino linker synthesis	-	-	NO
5956983	29896389	C.J.C.	2	contributed to the theoretical studies	contributed to the theoretical studies	-	Formal analysis	YES
5956983	29896389	D.R.	2	contributed to the theoretical studies	contributed to the theoretical studies	-	Formal analysis	YES
5956983	29896389	J.T.H.	2	conceived the project, design the experiments and wrote the manuscript	conceived the project, design the experiments and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
5956983	29896389	O.K.F.	2	conceived the project, design the experiments and wrote the manuscript	conceived the project, design the experiments and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
5956983	29896389	S.G.	2	conceived the project, design the experiments and wrote the manuscript|performed the synthesis and experiments	conceived the project, design the experiments and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
5956983	29896389	S.G.	2	conceived the project, design the experiments and wrote the manuscript|performed the synthesis and experiments	performed the synthesis and experiments	Performed the experiments	Investigation	YES
5956983	29896389	S.J.G.	2	contributed in amino linker synthesis	contributed in amino linker synthesis	-	-	NO
5956983	29896389	T.L.	2	contributed in amino linker synthesis	contributed in amino linker synthesis	-	-	NO
3917680	24342107	AK	2	supervised on the manuscript	supervised on the manuscript	-	Supervision	YES
3917680	24342107	KS	2	performed hplc analysis	performed hplc analysis	Performed the experiments	Investigation	YES
3917680	24342107	TH	2	critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
3917680	24342107	TTanaka	2	critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
3917680	24342107	TTateno	2	designed and constructed plasmids and strains	designed and constructed plasmids and strains	Conceived and designed the experiments|Performed the experiments	Investigation	YES
3917680	24342107	YT	2	performed bioprocess reaction, enzyme assay and wrote the manuscript	performed bioprocess reaction, enzyme assay and wrote the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
2631482	19138405	LD	2	participated in searching and reviewing scholarly databases and textbooks as well as contributing to the methodology and assisting in coordination of the project	participated in searching and reviewing scholarly databases and textbooks as well as contributing to the methodology and assisting in coordination of the project	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Methodology|Project administration|Software|Writing - Review & Editing	YES
2631482	19138405	LL	2	was responsible for conceptualizing the review, directing the project, searching and reviewing scholarly materials, and drafting the majority of the manuscript	was responsible for conceptualizing the review, directing the project, searching and reviewing scholarly materials, and drafting the majority of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
3817657	24228003	Chong Wang	2	contributed equally to this study and share first authorship	contributed equally to this study and share first authorship	-	-	NO
3817657	24228003	Xi-Jin Zhou	2	contributed equally to this study and share first authorship	contributed equally to this study and share first authorship	-	-	NO
5543444	28774272	All authors	2	were involved in drafting the manuscript or revising it critically for important intellectual content, gave final approval of the version to be published and agreed to be accountable for all aspects related to the accuracy or integrity of any part of the work	were involved in drafting the manuscript or revising it critically for important intellectual content, gave final approval of the version to be published and agreed to be accountable for all aspects related to the accuracy or integrity of any part of the work	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5543444	28774272	JMB	2	designed the study|acquired the data and carried out the analysis	designed the study	Conceived and designed the experiments	Methodology	YES
5543444	28774272	JMB	2	designed the study|acquired the data and carried out the analysis	acquired the data and carried out the analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5543444	28774272	LP	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5543444	28774272	NH	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5543444	28774272	all authors	2	contributed to the analysis and interpretation of data	contributed to the analysis and interpretation of data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
4411166	25915510	CH	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411166	25915510	GH	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411166	25915510	MK	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411166	25915510	MK	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411166	25915510	P. Kahlert	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411166	25915510	P. Kleinbongard	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411166	25915510	P. Kleinbongard	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411166	25915510	P. Kleinbongard	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411166	25915510	PH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411166	25915510	PH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411166	25915510	PH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411166	25915510	PH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411166	25915510	RE	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411166	25915510	RE	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411166	25915510	RW	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411166	25915510	TB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411166	25915510	TB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411166	25915510	TB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411166	25915510	TB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5118229	27873241	ACJ	2	participated in the design of the study, collected data, helped to perform statistical analysis, and drafted the manuscript	participated in the design of the study, collected data, helped to perform statistical analysis, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5118229	27873241	AED	2	performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
5118229	27873241	FJ	2	participated in the studys coordination	participated in the studys coordination	-	Project administration	YES
5118229	27873241	LM	2	participated in the studys coordination	participated in the studys coordination	-	Project administration	YES
5118229	27873241	MS	2	participated in the studys coordination	participated in the studys coordination	-	Project administration	YES
5118229	27873241	NA	2	conceived the study, helped to perform statistical analysis, and helped to draft the manuscript	conceived the study, helped to perform statistical analysis, and helped to draft the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
5118229	27873241	XT	2	participated in the studys coordination	participated in the studys coordination	-	Project administration	YES
5075683	27826423	CLL	2	were responsible for writing the manuscript	were responsible for writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5075683	27826423	GC	2	was responsible for drafting and revision of the manuscript	was responsible for drafting and revision of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5075683	27826423	KZ	2	were responsible for writing the manuscript	were responsible for writing the manuscript	Wrote the paper	Writing - Original Draft	YES
1849893	17440612	EW	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1849893	17440612	EW	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1849893	17440612	JB	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1849893	17440612	JB	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1849893	17440612	SD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1849893	17440612	SD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1849893	17440612	SD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1849893	17440612	SD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1849893	17440612	SD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1849893	17440612	UW	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1849893	17440612	UW	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5681962	29163626	BL	PLoS52	performed genetic mapping	performed genetic mapping	Performed the experiments	Investigation	YES
5681962	29163626	HH	PLoS52	conceived and designed the experiments|performed physical mapping|analyzed the data and wrote the paper|revised the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5681962	29163626	HH	PLoS52	conceived and designed the experiments|performed physical mapping|analyzed the data and wrote the paper|revised the paper	performed physical mapping	Performed the experiments	Investigation	YES
5681962	29163626	HH	PLoS52	conceived and designed the experiments|performed physical mapping|analyzed the data and wrote the paper|revised the paper	analyzed the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5681962	29163626	HH	PLoS52	conceived and designed the experiments|performed physical mapping|analyzed the data and wrote the paper|revised the paper	revised the paper	Wrote the paper	Writing - Review & Editing	YES
5681962	29163626	RZ	PLoS52	performed genetic mapping	performed genetic mapping	Performed the experiments	Investigation	YES
5681962	29163626	SZ	PLoS52	developed dna markers|analyzed the data and wrote the paper	developed dna markers	-	-	NO
5681962	29163626	SZ	PLoS52	developed dna markers|analyzed the data and wrote the paper	analyzed the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5681962	29163626	TB	PLoS52	conceived and designed the experiments|performed physical mapping|revised the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5681962	29163626	TB	PLoS52	conceived and designed the experiments|performed physical mapping|revised the paper	performed physical mapping	Performed the experiments	Investigation	YES
5681962	29163626	TB	PLoS52	conceived and designed the experiments|performed physical mapping|revised the paper	revised the paper	Wrote the paper	Writing - Review & Editing	YES
5681962	29163626	YJ	PLoS52	developed dna markers|performed genetic mapping	developed dna markers	-	-	NO
5681962	29163626	YJ	PLoS52	developed dna markers|performed genetic mapping	performed genetic mapping	Performed the experiments	Investigation	YES
5681962	29163626	ZJ	PLoS52	performed genetic mapping	performed genetic mapping	Performed the experiments	Investigation	YES
5110125	27867478	All authors	2	contributed equally to the manuscript, read and approved the final version of the paper for publication	contributed equally to the manuscript, read and approved the final version of the paper for publication	-	-	NO
3917702	24410821	CJF	2	designed experiments, all authors participated in data analysis	designed experiments, all authors participated in data analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
3917702	24410821	EPI	2	designed experiments, all authors participated in data analysis|drafted the manuscript	designed experiments, all authors participated in data analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
3917702	24410821	EPI	2	designed experiments, all authors participated in data analysis|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
3917702	24410821	HKW	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
3917702	24410821	RJC	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
3917702	24410821	VB	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
2637826	19087290	DSW	2	conceived the study, developed the study design, secured the funding for the project, assisted and provided oversight for all data acquisition and statistical analysis, assisted in drafting the manuscript, and served as the faculty mentor for the project	conceived the study, developed the study design, secured the funding for the project, assisted and provided oversight for all data acquisition and statistical analysis, assisted in drafting the manuscript, and served as the faculty mentor for the project	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Funding acquisition|Investigation|Methodology|Resources|Supervision|Writing - Original Draft	YES
2637826	19087290	EN	2	participated in the data acquisition	participated in the data acquisition	Performed the experiments	Investigation	YES
2637826	19087290	GH	2	participated in the data acquisition	participated in the data acquisition	Performed the experiments	Investigation	YES
2637826	19087290	JC	2	participated in the data acquisition	participated in the data acquisition	Performed the experiments	Investigation	YES
2637826	19087290	JJ	2	participated in the design of the study, coordination and data acquisition, and assisted in performing the statistical analysis and drafting the manuscript	participated in the design of the study, coordination and data acquisition, and assisted in performing the statistical analysis and drafting the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Project administration|Writing - Original Draft	YES
2637826	19087290	JM	2	participated in the data acquisition	participated in the data acquisition	Performed the experiments	Investigation	YES
2637826	19087290	MC	2	assisted in graduate student supervision and participated data acquisition	assisted in graduate student supervision and participated data acquisition	Performed the experiments	Investigation|Supervision	YES
2637826	19087290	RK	2	assisted with providing graduate student funding and laboratory availability	assisted with providing graduate student funding and laboratory availability	-	Funding acquisition	YES
2637826	19087290	TB	2	participated in the data acquisition	participated in the data acquisition	Performed the experiments	Investigation	YES
5118230	27873239	HO	2	carried out the data analysis and drafted the manuscript	carried out the data analysis and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5118230	27873239	HT	2	conceived of the study and participated in its design and coodination	conceived of the study and participated in its design and coodination	Conceived and designed the experiments	Conceptualization|Methodology	YES
5118230	27873239	MK	2	carried out the pet probe synthesis	carried out the pet probe synthesis	Performed the experiments	Investigation	YES
5118230	27873239	TK	2	carried out animal handring	carried out animal handring	Performed the experiments	Investigation	YES
1849894	17440614	AT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1849894	17440614	AT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1849894	17440614	AT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1849894	17440614	BM	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1849894	17440614	BM	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1849894	17440614	DT	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1849894	17440614	DT	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1849894	17440614	KZ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1849894	17440614	KZ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1849894	17440614	KZ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1849894	17440614	MO	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1849894	17440614	OM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1849894	17440614	OM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1849894	17440614	OM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1849894	17440614	OM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1849894	17440614	VZ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5543532	28774270	AD	PLoS52	provided tools for bioinformatics analysis	provided tools for bioinformatics analysis	Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5543532	28774270	All authors	PLoS52	participated in the acquisition of data and the revision of the manuscript|read and approved the final version to be published|agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	participated in the acquisition of data and the revision of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5543532	28774270	All authors	PLoS52	participated in the acquisition of data and the revision of the manuscript|read and approved the final version to be published|agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	read and approved the final version to be published	-	-	NO
5543532	28774270	All authors	PLoS52	participated in the acquisition of data and the revision of the manuscript|read and approved the final version to be published|agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	-	-	NO
5543532	28774270	CG	PLoS52	prepared the samples	prepared the samples	Performed the experiments	Investigation	YES
5543532	28774270	DS	PLoS52	involved in steering committee of the project|conceived and designed the experiments|significantly contributed to the revision of the manuscript	involved in steering committee of the project	-	-	NO
5543532	28774270	DS	PLoS52	involved in steering committee of the project|conceived and designed the experiments|significantly contributed to the revision of the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5543532	28774270	DS	PLoS52	involved in steering committee of the project|conceived and designed the experiments|significantly contributed to the revision of the manuscript	significantly contributed to the revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5543532	28774270	FL	PLoS52	involved in steering committee of the project|significantly contributed to the revision of the manuscript	involved in steering committee of the project	-	-	NO
5543532	28774270	FL	PLoS52	involved in steering committee of the project|significantly contributed to the revision of the manuscript	significantly contributed to the revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5543532	28774270	SB	PLoS52	involved in steering committee of the project|significantly contributed to the revision of the manuscript	involved in steering committee of the project	-	-	NO
5543532	28774270	SB	PLoS52	involved in steering committee of the project|significantly contributed to the revision of the manuscript	significantly contributed to the revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5543532	28774270	SC	PLoS52	provided tools for bioinformatics analysis	provided tools for bioinformatics analysis	Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5543532	28774270	VN	PLoS52	provided tools for bioinformatics analysis	provided tools for bioinformatics analysis	Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5543532	28774270	WG	PLoS52	involved in steering committee of the project|conceived and designed the experiments|performed the experiments|prepared the samples|performed bioinformatics analyses, interpreted the data and wrote the manuscript	involved in steering committee of the project	-	-	NO
5543532	28774270	WG	PLoS52	involved in steering committee of the project|conceived and designed the experiments|performed the experiments|prepared the samples|performed bioinformatics analyses, interpreted the data and wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5543532	28774270	WG	PLoS52	involved in steering committee of the project|conceived and designed the experiments|performed the experiments|prepared the samples|performed bioinformatics analyses, interpreted the data and wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5543532	28774270	WG	PLoS52	involved in steering committee of the project|conceived and designed the experiments|performed the experiments|prepared the samples|performed bioinformatics analyses, interpreted the data and wrote the manuscript	prepared the samples	Performed the experiments	Investigation	YES
5543532	28774270	WG	PLoS52	involved in steering committee of the project|conceived and designed the experiments|performed the experiments|prepared the samples|performed bioinformatics analyses, interpreted the data and wrote the manuscript	performed bioinformatics analyses, interpreted the data and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5681966	29163628	JX	2	provided biochemical and molecular analysis support and management	provided biochemical and molecular analysis support and management	Performed the experiments	Investigation	YES
5681966	29163628	MY	2	performed most of the experiments and analyzed the data|designed the research, supervised the project, interpreted data, and drafted and revised the manuscript	performed most of the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5681966	29163628	MY	2	performed most of the experiments and analyzed the data|designed the research, supervised the project, interpreted data, and drafted and revised the manuscript	designed the research, supervised the project, interpreted data, and drafted and revised the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
5681966	29163628	RH	2	performed most of the experiments and analyzed the data	performed most of the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5681966	29163628	SH	2	performed most of the experiments and analyzed the data	performed most of the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5681966	29163628	SW	2	designed the research, supervised the project, interpreted data, and drafted and revised the manuscript	designed the research, supervised the project, interpreted data, and drafted and revised the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
5681966	29163628	XL	2	provided biochemical and molecular analysis support and management	provided biochemical and molecular analysis support and management	Performed the experiments	Investigation	YES
4411168	25915421	CL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411168	25915421	DQ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411168	25915421	FCY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411168	25915421	FCY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411168	25915421	FCY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411168	25915421	FCY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411168	25915421	JW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411168	25915421	JW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411168	25915421	JW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411168	25915421	WK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4411168	25915421	WS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5110126	27867475	HJH	2	searched the references and wrote the paper	searched the references and wrote the paper	Wrote the paper	Writing - Original Draft	YES
5110126	27867475	QS	2	searched the references and wrote the paper	searched the references and wrote the paper	Wrote the paper	Writing - Original Draft	YES
5110126	27867475	XJS	2	designed the study|revised the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5110126	27867475	XJS	2	designed the study|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5110126	27867475	ZHY	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5122527	27885618	AMDB	PLoS52	drafted the manuscript|analysed the data	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5122527	27885618	AMDB	PLoS52	drafted the manuscript|analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
5122527	27885618	All authors	PLoS52	proposed valuable comments, revise the manuscript critically for important intellectual content and approved the final manuscript	proposed valuable comments, revise the manuscript critically for important intellectual content and approved the final manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5122527	27885618	SAE	PLoS52	procured the icr12 antibody	procured the icr12 antibody	Performed the experiments	Investigation	YES
5122527	27885618	SEC	PLoS52	collected the imaging data|analysed the data	collected the imaging data	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
5122527	27885618	SEC	PLoS52	collected the imaging data|analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
5122527	27885618	TS	PLoS52	collected the imaging data	collected the imaging data	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
5544998	28778154	AP	2	designed the model and wrote the paper	designed the model and wrote the paper	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5544998	28778154	ME	2	contributed the software and analysis of oscillation phase	contributed the software and analysis of oscillation phase	Contributed reagents/materials/analysis tools	Software	YES
5544998	28778154	NP	2	designed the model and provided analytical solution	designed the model and provided analytical solution	Conceived and designed the experiments|Performed the experiments	Methodology	YES
5544998	28778154	SB	2	performed data mining and extraction of specific patterns of expression in multiple data	performed data mining and extraction of specific patterns of expression in multiple data	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
2645359	19175919	AAW	2	were responsible for data collection, blood collection and processing	were responsible for data collection, blood collection and processing	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
2645359	19175919	BJC	2	were responsible for data collection, blood collection and processing	were responsible for data collection, blood collection and processing	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
2645359	19175919	BKS	2	was responsible for the study design and manuscript preparation	was responsible for the study design and manuscript preparation	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
2645359	19175919	KGH	2	were responsible for data collection, blood collection and processing	were responsible for data collection, blood collection and processing	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
2645359	19175919	KHFW	2	were responsible for data collection, blood collection and processing	were responsible for data collection, blood collection and processing	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
2645359	19175919	RJB	2	was responsible for the study design, biochemical work, statistical analyses, and manuscript preparation	was responsible for the study design, biochemical work, statistical analyses, and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5110127	27867474	CHH	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5110127	27867474	JZ	PLoS52	collected literatures	collected literatures	Performed the experiments	Formal analysis|Investigation	YES
5110127	27867474	KL	PLoS52	collected literatures	collected literatures	Performed the experiments	Formal analysis|Investigation	YES
5110127	27867474	PXZ	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5110127	27867474	WWL	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5110127	27867474	XJS	PLoS52	designed this paper	designed this paper	Conceived and designed the experiments	-	YES
1849965	17460757	JB	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1849965	17460757	JB	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1849965	17460757	JC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1849965	17460757	JH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1849965	17460757	JH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1849965	17460757	JH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1849965	17460757	JK	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1849965	17460757	JK	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1849965	17460757	PL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1849965	17460757	PL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1849965	17460757	PL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1849965	17460757	PL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411170	25915744	DPX	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4411170	25915744	DPX	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411170	25915744	MYD	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411170	25915744	NNQ	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411170	25915744	NNQ	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4411170	25915744	NNQ	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411170	25915744	WGH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411170	25915744	WGH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411170	25915744	WGH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411170	25915744	WGH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411170	25915744	ZKX	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4411170	25915744	ZKX	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4411170	25915744	ZKX	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5681967	29163613	BK	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5681967	29163613	MS	PLoS52	conceived and designed the experiments|conducted the experiments and analyzed the data|wrote the manuscript and all authors contributed to editing the final manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5681967	29163613	MS	PLoS52	conceived and designed the experiments|conducted the experiments and analyzed the data|wrote the manuscript and all authors contributed to editing the final manuscript	conducted the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5681967	29163613	MS	PLoS52	conceived and designed the experiments|conducted the experiments and analyzed the data|wrote the manuscript and all authors contributed to editing the final manuscript	wrote the manuscript and all authors contributed to editing the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5681967	29163613	RV	PLoS52	conducted the experiments and analyzed the data	conducted the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5681967	29163613	ST	PLoS52	conceived and designed the experiments|conducted the experiments and analyzed the data|wrote the manuscript and all authors contributed to editing the final manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5681967	29163613	ST	PLoS52	conceived and designed the experiments|conducted the experiments and analyzed the data|wrote the manuscript and all authors contributed to editing the final manuscript	conducted the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5681967	29163613	ST	PLoS52	conceived and designed the experiments|conducted the experiments and analyzed the data|wrote the manuscript and all authors contributed to editing the final manuscript	wrote the manuscript and all authors contributed to editing the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3922913	24160319	ATRV	PLoS5	Contributed for the reagents/materials|Participated in the design and coordination of the study	Contributed for the reagents/materials	Contributed reagents/materials/analysis tools	Resources	YES
3922913	24160319	ATRV	PLoS5	Contributed for the reagents/materials|Participated in the design and coordination of the study	Participated in the design and coordination of the study	Conceived and designed the experiments	Methodology|Project administration	YES
3922913	24160319	CET	PLoS5	Analyzed the statistical, taxonomic, and comparative data|Analyzed the functional data|Wrote the manuscript	Analyzed the statistical, taxonomic, and comparative data	Analyzed the data	Formal analysis	YES
3922913	24160319	CET	PLoS5	Analyzed the statistical, taxonomic, and comparative data|Analyzed the functional data|Wrote the manuscript	Analyzed the functional data	Analyzed the data	Formal analysis	YES
3922913	24160319	CET	PLoS5	Analyzed the statistical, taxonomic, and comparative data|Analyzed the functional data|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3922913	24160319	JAG	PLoS5	Contributed for the reagents/materials|Participated in the design and coordination of the study	Contributed for the reagents/materials	Contributed reagents/materials/analysis tools	Resources	YES
3922913	24160319	JAG	PLoS5	Contributed for the reagents/materials|Participated in the design and coordination of the study	Participated in the design and coordination of the study	Conceived and designed the experiments	Methodology|Project administration	YES
3922913	24160319	LS	PLoS5	Analyzed the experimental data|Analyzed the functional data|Wrote the manuscript	Analyzed the experimental data	Analyzed the data	Formal analysis	YES
3922913	24160319	LS	PLoS5	Analyzed the experimental data|Analyzed the functional data|Wrote the manuscript	Analyzed the functional data	Analyzed the data	Formal analysis	YES
3922913	24160319	LS	PLoS5	Analyzed the experimental data|Analyzed the functional data|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3922913	24160319	MB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
3922913	24160319	MHV	PLoS5	Contributed for the reagents/materials|Participated in the design and coordination of the study	Contributed for the reagents/materials	Contributed reagents/materials/analysis tools	Resources	YES
3922913	24160319	MHV	PLoS5	Contributed for the reagents/materials|Participated in the design and coordination of the study	Participated in the design and coordination of the study	Conceived and designed the experiments	Methodology|Project administration	YES
3922913	24160319	WOB	PLoS5	Analyzed the experimental data	Analyzed the experimental data	Analyzed the data	Formal analysis	YES
3922913	24160319	WOBS	PLoS5	Analyzed the functional data|Contributed for the reagents/materials|Wrote the manuscript	Analyzed the functional data	Analyzed the data	Formal analysis	YES
3922913	24160319	WOBS	PLoS5	Analyzed the functional data|Contributed for the reagents/materials|Wrote the manuscript	Contributed for the reagents/materials	Contributed reagents/materials/analysis tools	Resources	YES
3922913	24160319	WOBS	PLoS5	Analyzed the functional data|Contributed for the reagents/materials|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5545021	28778147	AAS	2	developed the rnai mutants with differential concentrations of organic acids	developed the rnai mutants with differential concentrations of organic acids	Performed the experiments	Investigation	YES
5545021	28778147	AKD	2	performed the experiments and validations	performed the experiments and validations	Performed the experiments	Investigation|Validation	YES
5545021	28778147	DK	2	performed qrt-pcr analyses	performed qrt-pcr analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5545021	28778147	DM	2	performed the inoculation experiments	performed the inoculation experiments	Performed the experiments	Investigation	YES
5545021	28778147	DP	2	conceived and supervised the project, and drafted the manuscript	conceived and supervised the project, and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Supervision|Writing - Original Draft	YES
5545021	28778147	NL	2	performed the rna extractions	performed the rna extractions	Performed the experiments	Investigation	YES
5545021	28778147	NS	2	performed the bioinformatics analyses and drafted the manuscript	performed the bioinformatics analyses and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5545021	28778147	SB	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5545021	28778147	SC	2	developed the rnai mutants with differential concentrations of organic acids	developed the rnai mutants with differential concentrations of organic acids	Performed the experiments	Investigation	YES
5110128	27867468	MS	2	exclusively contributed to the study, read and approved the final version of this paper	exclusively contributed to the study, read and approved the final version of this paper	-	-	NO
5124015	27888500	All authors	2	contributed actively to the editing of the article and read and approved the final version	contributed actively to the editing of the article and read and approved the final version	Wrote the paper	Writing - Review & Editing	YES
5124015	27888500	GB	2	in the data analysis	in the data analysis	Analyzed the data	Formal analysis	YES
5124015	27888500	MSB	2	conducted the experiments, performed the analysis and wrote the text for this article|assisted in all aspects of the work	conducted the experiments, performed the analysis and wrote the text for this article	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5124015	27888500	MSB	2	conducted the experiments, performed the analysis and wrote the text for this article|assisted in all aspects of the work	assisted in all aspects of the work	-	-	NO
5124015	27888500	RF	2	was involved in the implementation of the motion compensation technique	was involved in the implementation of the motion compensation technique	Performed the experiments	Investigation	YES
2649036	19210788	All authors	2	contributed equally to this work	contributed equally to this work	-	-	NO
1849966	17460759	AV	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1849966	17460759	AV	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1849966	17460759	AV	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1849966	17460759	MH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1849966	17460759	MH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1849966	17460759	MH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1849966	17460759	MM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1849966	17460759	RN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1849966	17460759	RN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1849966	17460759	RN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1849966	17460759	RN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1849966	17460759	SC	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1849966	17460759	SC	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1849966	17460759	SR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1849966	17460759	SR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1849966	17460759	SR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411171	25915061	CH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411171	25915061	CH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411171	25915061	CH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411171	25915061	CH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411171	25915061	CH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411171	25915061	HSB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411171	25915061	HSB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411171	25915061	HSB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411171	25915061	HSB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411171	25915061	HSB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411171	25915061	LB	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411171	25915061	LB	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411171	25915061	LB	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411171	25915061	LB	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411171	25915061	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411171	25915061	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411171	25915061	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411171	25915061	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411171	25915061	OK	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411171	25915061	OK	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4575723	26425545	Detu Zhu	2	are equal contributors	are equal contributors	-	-	NO
4575723	26425545	Yumei Luo	2	are equal contributors	are equal contributors	-	-	NO
4575723	26425545	Zikai Chen	2	are equal contributors	are equal contributors	-	-	NO
5681968	29163574	CA	PLoS52	conceived and designed the study|analyzed the data|wrote the paper	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5681968	29163574	CA	PLoS52	conceived and designed the study|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5681968	29163574	CA	PLoS52	conceived and designed the study|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5681968	29163574	JD	PLoS52	performed the research	performed the research	Performed the experiments	Investigation	YES
5681968	29163574	MB	PLoS52	performed the research	performed the research	Performed the experiments	Investigation	YES
5681968	29163574	NK	PLoS52	conceived and designed the study|performed the research|analyzed the data|wrote the paper	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5681968	29163574	NK	PLoS52	conceived and designed the study|performed the research|analyzed the data|wrote the paper	performed the research	Performed the experiments	Investigation	YES
5681968	29163574	NK	PLoS52	conceived and designed the study|performed the research|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5681968	29163574	NK	PLoS52	conceived and designed the study|performed the research|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5681968	29163574	RG	PLoS52	analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5681968	29163574	RG	PLoS52	analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
2649889	19228401	DSW	2	conceived the study, developed the study design, secured the funding for the project, assisted and provided oversight for all data acquisition and statistical analysis, assisted in drafting the manuscript, and served as the faculty mentor for the project	conceived the study, developed the study design, secured the funding for the project, assisted and provided oversight for all data acquisition and statistical analysis, assisted in drafting the manuscript, and served as the faculty mentor for the project	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Funding acquisition|Investigation|Methodology|Resources|Supervision|Writing - Original Draft	YES
2649889	19228401	MC	2	participated in the data acquisition	participated in the data acquisition	Performed the experiments	Investigation	YES
2649889	19228401	MG	2	assisted with the design of the study	assisted with the design of the study	Conceived and designed the experiments	Methodology	YES
2649889	19228401	MS	2	assisted in coordination of the study, data acquisition, in performing the statistical analysis, and drafting the manuscript	assisted in coordination of the study, data acquisition, in performing the statistical analysis, and drafting the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Project administration|Writing - Original Draft	YES
2649889	19228401	RK	2	assisted with the design of the study|also secured the donation of the creatine ethyl ester supplement, and assisted in the statistical analysis and manuscript preparation	assisted with the design of the study	Conceived and designed the experiments	Methodology	YES
2649889	19228401	RK	2	assisted with the design of the study|also secured the donation of the creatine ethyl ester supplement, and assisted in the statistical analysis and manuscript preparation	also secured the donation of the creatine ethyl ester supplement, and assisted in the statistical analysis and manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
2649889	19228401	RS	2	participated in the data acquisition	participated in the data acquisition	Performed the experiments	Investigation	YES
2649889	19228401	TH	2	participated in the data acquisition	participated in the data acquisition	Performed the experiments	Investigation	YES
5110129	27867473	GC	2	responsible for its drafting and revision	responsible for its drafting and revision	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4581549	26448754	Carol S. Trempus	2	contributed equally as first authors	contributed equally as first authors	-	-	NO
4581549	26448754	Jaime M. Cyphert	2	contributed equally as first authors	contributed equally as first authors	-	-	NO
5545033	28778155	BL	2	performed the bioinformatics analysis	performed the bioinformatics analysis	Performed the experiments	Formal analysis|Investigation	YES
5545033	28778155	CW	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5545033	28778155	JY	2	performed the bioinformatics analysis	performed the bioinformatics analysis	Performed the experiments	Formal analysis|Investigation	YES
5545033	28778155	LC	2	performed the bioinformatics analysis	performed the bioinformatics analysis	Performed the experiments	Formal analysis|Investigation	YES
5545033	28778155	LW	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5545033	28778155	QJ	2	designed and supervised the research	designed and supervised the research	Conceived and designed the experiments	Methodology|Supervision	YES
5545033	28778155	TL	2	performed experiments|wrote the manuscript	performed experiments	Performed the experiments	Investigation	YES
5545033	28778155	TL	2	performed experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5545033	28778155	XX	2	performed experiments|wrote the manuscript	performed experiments	Performed the experiments	Investigation	YES
5545033	28778155	XX	2	performed experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
1849967	17460760	FT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1849967	17460760	FT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1849967	17460760	FT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1849967	17460760	FT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1849967	17460760	FT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1849967	17460760	MR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1849967	17460760	MR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1849967	17460760	MR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1849967	17460760	MR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1849967	17460760	MR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1849967	17460760	PP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1849967	17460760	PP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1849967	17460760	PP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1849967	17460760	PP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411172	25915931	DL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411172	25915931	DL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411172	25915931	DL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411172	25915931	DL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411172	25915931	JP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411172	25915931	JP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411172	25915931	JP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411172	25915931	JP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411172	25915931	KH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411172	25915931	KH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411172	25915931	KH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411172	25915931	KH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411172	25915931	SY	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411172	25915931	SY	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5126032	27896673	JS	2	was a principal investigator	was a principal investigator	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
4016035	24034235	JT	2	designed and performed the experimental work and participated in writing the manuscript	designed and performed the experimental work and participated in writing the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
4016035	24034235	LG	2	designed the study and participated in writing of the manuscript	designed the study and participated in writing of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4016035	24034235	LS	2	designed and performed the experimental work and participated in writing the manuscript	designed and performed the experimental work and participated in writing the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
4016035	24034235	TS	2	designed and performed the experimental work and participated in writing the manuscript	designed and performed the experimental work and participated in writing the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5682030	29163618	AM	PLoS52	designed experiments, performed experiments, and analyzed data|wrote the paper	designed experiments, performed experiments, and analyzed data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5682030	29163618	AM	PLoS52	designed experiments, performed experiments, and analyzed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5682030	29163618	YS	PLoS52	designed experiments, performed experiments, and analyzed data	designed experiments, performed experiments, and analyzed data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5682030	29163618	YW	PLoS52	designed experiments, performed experiments, and analyzed data	designed experiments, performed experiments, and analyzed data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
2651845	19250531	ADF	2	were co-authors, oversaw all aspects of study including recruitment, data/specimen analysis, and manuscript preparation	were co-authors, oversaw all aspects of study including recruitment, data/specimen analysis, and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Supervision|Writing - Original Draft	YES
2651845	19250531	JK	2	were co-authors, oversaw all aspects of study including recruitment, data/specimen analysis, and manuscript preparation	were co-authors, oversaw all aspects of study including recruitment, data/specimen analysis, and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Supervision|Writing - Original Draft	YES
2651845	19250531	JRH	2	was the primary investigator, obtained grant funds for project, designed study, supervised all study recruitment, data/specimen analysis, statistical analysis and manuscript preparation	was the primary investigator, obtained grant funds for project, designed study, supervised all study recruitment, data/specimen analysis, statistical analysis and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Funding acquisition|Investigation|Methodology|Supervision|Writing - Original Draft	YES
2651845	19250531	NAR	2	were co-authors, oversaw all aspects of study including recruitment, data/specimen analysis, and manuscript preparation	were co-authors, oversaw all aspects of study including recruitment, data/specimen analysis, and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Supervision|Writing - Original Draft	YES
2651845	19250531	SLR	2	were co-authors, oversaw all aspects of study including recruitment, data/specimen analysis, and manuscript preparation	were co-authors, oversaw all aspects of study including recruitment, data/specimen analysis, and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Supervision|Writing - Original Draft	YES
5110132	27867476	AM	2	reviewed the studies in animal models	reviewed the studies in animal models	Performed the experiments	Methodology	YES
5110132	27867476	JT	2	modified the language	modified the language	-	-	NO
5110132	27867476	JZ	2	modified the language	modified the language	-	-	NO
5110132	27867476	QH	2	write the paper	write the paper	Wrote the paper	Writing - Original Draft	YES
5110132	27867476	TX	2	reviewed the studies on clinic	reviewed the studies on clinic	-	-	NO
5110132	27867476	ZG	2	reviewed the studies on clinic	reviewed the studies on clinic	-	-	NO
1849968	17460755	GC	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1849968	17460755	GC	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1849968	17460755	GK	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1849968	17460755	HB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1849968	17460755	HB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1849968	17460755	HB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1849968	17460755	HB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1849968	17460755	HK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1849968	17460755	HK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1849968	17460755	TP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1849968	17460755	TP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5151115	27957720	BL	2	designed the nuclear medicine part of the study, read the scintigraphies and processed the data|contributed equally to this manuscript	designed the nuclear medicine part of the study, read the scintigraphies and processed the data	Conceived and designed the experiments|Analyzed the data	Data curation|Methodology	YES
5151115	27957720	BL	2	designed the nuclear medicine part of the study, read the scintigraphies and processed the data|contributed equally to this manuscript	contributed equally to this manuscript	-	-	NO
5151115	27957720	CD	2	performed in vitro work and supervised the section on biodistribution	performed in vitro work and supervised the section on biodistribution	Performed the experiments	Investigation|Supervision	YES
5151115	27957720	DE	2	designed the study and supervised the processing of clinical data	designed the study and supervised the processing of clinical data	Conceived and designed the experiments|Analyzed the data	Data curation|Methodology|Supervision	YES
5151115	27957720	FDV	2	developped the radiolabelling procedure and designed, performed and supervised the stability study and biodistribution study	developped the radiolabelling procedure and designed, performed and supervised the stability study and biodistribution study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Supervision	YES
5151115	27957720	FVdB	2	designed the study and supervised the processing of clinical data	designed the study and supervised the processing of clinical data	Conceived and designed the experiments|Analyzed the data	Data curation|Methodology|Supervision	YES
5151115	27957720	GV	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5151115	27957720	KB	2	was responsible for the dosimetry section	was responsible for the dosimetry section	-	-	NO
5151115	27957720	PC	2	designed the clinical part of the study, was involved in patient recruitement including clinical and ultrasound assessment of all patients and data processing|contributed equally to this manuscript	designed the clinical part of the study, was involved in patient recruitement including clinical and ultrasound assessment of all patients and data processing	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Data curation|Investigation|Methodology	YES
5151115	27957720	PC	2	designed the clinical part of the study, was involved in patient recruitement including clinical and ultrasound assessment of all patients and data processing|contributed equally to this manuscript	contributed equally to this manuscript	-	-	NO
5151115	27957720	RB	2	performed the in vitro study	performed the in vitro study	Performed the experiments	Investigation	YES
5151115	27957720	YD	2	was responsible for the dosimetry section	was responsible for the dosimetry section	-	-	NO
5545040	28778149	DF	2	did the assemblies and analyses|wrote the manuscript	did the assemblies and analyses	Analyzed the data	Formal analysis	YES
5545040	28778149	DF	2	did the assemblies and analyses|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5545040	28778149	JM	2	conceived and designed this research|did the assemblies and analyses|wrote the manuscript	conceived and designed this research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5545040	28778149	JM	2	conceived and designed this research|did the assemblies and analyses|wrote the manuscript	did the assemblies and analyses	Analyzed the data	Formal analysis	YES
5545040	28778149	JM	2	conceived and designed this research|did the assemblies and analyses|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5545040	28778149	JRM	2	conceived and designed this research|edited the manuscript	conceived and designed this research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5545040	28778149	JRM	2	conceived and designed this research|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5545040	28778149	KATS	2	conceived and designed this research|edited the manuscript	conceived and designed this research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5545040	28778149	KATS	2	conceived and designed this research|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5545040	28778149	KMM	2	did the assemblies and analyses|wrote the manuscript	did the assemblies and analyses	Analyzed the data	Formal analysis	YES
5545040	28778149	KMM	2	did the assemblies and analyses|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5545040	28778149	MJS	2	generated the r108 rna seq data|edited the manuscript	generated the r108 rna seq data	Performed the experiments	Investigation	YES
5545040	28778149	MJS	2	generated the r108 rna seq data|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5545040	28778149	NDY	2	conceived and designed this research|edited the manuscript	conceived and designed this research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5545040	28778149	NDY	2	conceived and designed this research|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5545040	28778149	NPD	2	did the assemblies and analyses	did the assemblies and analyses	Analyzed the data	Formal analysis	YES
5545040	28778149	PT	2	conceived and designed this research|edited the manuscript	conceived and designed this research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5545040	28778149	PT	2	conceived and designed this research|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5545040	28778149	PZ	2	did the assemblies and analyses|wrote the manuscript	did the assemblies and analyses	Analyzed the data	Formal analysis	YES
5545040	28778149	PZ	2	did the assemblies and analyses|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5545040	28778149	RMS	2	generated the r108 rna seq data|edited the manuscript	generated the r108 rna seq data	Performed the experiments	Investigation	YES
5545040	28778149	RMS	2	generated the r108 rna seq data|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5545040	28778149	TR	2	did the assemblies and analyses|wrote the manuscript	did the assemblies and analyses	Analyzed the data	Formal analysis	YES
5545040	28778149	TR	2	did the assemblies and analyses|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4575730	26425555	Hua Tao	2	contributed equally to this work	contributed equally to this work	-	-	NO
4575730	26425555	Lili Cui	2	contributed equally to this work	contributed equally to this work	-	-	NO
4575730	26425555	You Li	2	contributed equally to this work	contributed equally to this work	-	-	NO
5110133	27867477	GC	2	was responsible for its drafting and revision	was responsible for its drafting and revision	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5110133	27867477	LS	2	were responsible for writing the manuscript	were responsible for writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5110133	27867477	WWZ	2	were responsible for writing the manuscript	were responsible for writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5110133	27867477	ZQY	2	was responsible for its revision	was responsible for its revision	Wrote the paper	Writing - Review & Editing	YES
5682033	29163620	AP	2	conceived and designed the study|supervised the analytical and biochemical studies	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5682033	29163620	AP	2	conceived and designed the study|supervised the analytical and biochemical studies	supervised the analytical and biochemical studies	Performed the experiments	Investigation|Supervision	YES
5682033	29163620	All authors	2	discussed and commented the manuscript	discussed and commented the manuscript	-	-	NO
5682033	29163620	CR-S	2	performed the cloning and qrt-pcr experiments	performed the cloning and qrt-pcr experiments	Performed the experiments	Investigation	YES
5682033	29163620	DV-P	2	performed the cloning and qrt-pcr experiments|carried out the immunological studies|performed the transient expression experiments and the analytical and biochemical studies	performed the cloning and qrt-pcr experiments	Performed the experiments	Investigation	YES
5682033	29163620	DV-P	2	performed the cloning and qrt-pcr experiments|carried out the immunological studies|performed the transient expression experiments and the analytical and biochemical studies	carried out the immunological studies	Performed the experiments	Investigation	YES
5682033	29163620	DV-P	2	performed the cloning and qrt-pcr experiments|carried out the immunological studies|performed the transient expression experiments and the analytical and biochemical studies	performed the transient expression experiments and the analytical and biochemical studies	Performed the experiments	Investigation	YES
5682033	29163620	FV	2	supervised the transient expression experiments	supervised the transient expression experiments	Performed the experiments	Investigation|Supervision	YES
5682033	29163620	IG	2	supervised the transient expression experiments	supervised the transient expression experiments	Performed the experiments	Investigation|Supervision	YES
5682033	29163620	JM-R	2	conceived and designed the study|supervised the cloning, qrt pcr and immunological studies|wrote the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5682033	29163620	JM-R	2	conceived and designed the study|supervised the cloning, qrt pcr and immunological studies|wrote the manuscript	supervised the cloning, qrt pcr and immunological studies	Performed the experiments	Investigation|Supervision	YES
5682033	29163620	JM-R	2	conceived and designed the study|supervised the cloning, qrt pcr and immunological studies|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5682033	29163620	MH	2	supervised the cloning, qrt pcr and immunological studies	supervised the cloning, qrt pcr and immunological studies	Performed the experiments	Investigation|Supervision	YES
5682033	29163620	RG-R	2	carried out the immunological studies	carried out the immunological studies	Performed the experiments	Investigation	YES
2654424	19077317	AB	2	designed the study, developed the questionnaire and collected the data	designed the study, developed the questionnaire and collected the data	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
2654424	19077317	AP	2	carried out the analysis and drafted the manuscript	carried out the analysis and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
2654424	19077317	DPN	2	carried out the analysis and drafted the manuscript	carried out the analysis and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
2654424	19077317	GP	2	contributed to data collection and prepared the data set for statistical analysis	contributed to data collection and prepared the data set for statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
2654424	19077317	MMcN	2	designed the study, developed the questionnaire and collected the data	designed the study, developed the questionnaire and collected the data	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
2654424	19077317	RB	2	designed the study, developed the questionnaire and collected the data	designed the study, developed the questionnaire and collected the data	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4411174	25915756	BM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411174	25915756	BM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411174	25915756	BM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411174	25915756	HB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411174	25915756	HB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411174	25915756	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4411174	25915756	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4411174	25915756	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411174	25915756	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411174	25915756	JCW	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411174	25915756	JCW	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411174	25915756	JCW	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411174	25915756	SP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4411174	25915756	SP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4411174	25915756	SP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1851096	17460758	FV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1851096	17460758	FV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1851096	17460758	FV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1851096	17460758	FV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1851096	17460758	JC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1851096	17460758	JC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1851096	17460758	JC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1851096	17460758	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1851096	17460758	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1851096	17460758	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1851096	17460758	KS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1851096	17460758	KS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1851096	17460758	KS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1851096	17460758	KS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1851096	17460758	RP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1851096	17460758	RP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1851096	17460758	RP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5110134	27867469	BH	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5110134	27867469	JEB	PLoS52	performed data analysis and wrote the manuscript	performed data analysis and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5110134	27867469	JHA	PLoS52	performed data analysis and wrote the manuscript	performed data analysis and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5110134	27867469	JJR	PLoS52	performed data analysis and wrote the manuscript	performed data analysis and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5110134	27867469	LC	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5110134	27867469	MD	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5110134	27867469	NV	PLoS52	performed data analysis and wrote the manuscript	performed data analysis and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5110134	27867469	SB	PLoS52	performed data analysis and wrote the manuscript	performed data analysis and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5153383	27957721	ASP	2	were involved in the study design, implementation, analysis, and manuscript preparation	were involved in the study design, implementation, analysis, and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5153383	27957721	LKF	2	were involved in the study design, implementation, analysis, and manuscript preparation	were involved in the study design, implementation, analysis, and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5153383	27957721	RFA	2	treatment-planning simulator and assisted in the manuscript preparation|probe placement for ablation and the manuscript preparation	treatment-planning simulator and assisted in the manuscript preparation	Conceived and designed the experiments|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5153383	27957721	RFA	2	treatment-planning simulator and assisted in the manuscript preparation|probe placement for ablation and the manuscript preparation	probe placement for ablation and the manuscript preparation	Wrote the paper	Writing - Original Draft	YES
5153383	27957721	SK	2	assisted in the manuscript preparation and patient identification	assisted in the manuscript preparation and patient identification	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5153383	27957721	YCB	2	were involved in the study design, implementation, analysis, and manuscript preparation	were involved in the study design, implementation, analysis, and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
4052627	24949276	CRCMZ	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4052627	24949276	WMWY	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5682034	29163621	JC	2	designed and carried out the experiment of this study, and wrote the manuscript	designed and carried out the experiment of this study, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5682034	29163621	SY	2	participated and analyzed data in the experiment	participated and analyzed data in the experiment	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5682034	29163621	W-MT	2	planned the study and participated in the design of the experiment	planned the study and participated in the design of the experiment	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
5682034	29163621	YC	2	participated and analyzed data in the experiment	participated and analyzed data in the experiment	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4411262	25786210	AHW	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411262	25786210	CFD	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4411262	25786210	DBL	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5545845	28784084	ALB	2	performed rna isolation and qrt-pcr analysis	performed rna isolation and qrt-pcr analysis	Performed the experiments	Investigation	YES
5545845	28784084	BK	2	conceived and designed the study|wrote the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5545845	28784084	BK	2	conceived and designed the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5545845	28784084	LLC	2	carried out all data analyses|wrote the manuscript	carried out all data analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5545845	28784084	LLC	2	carried out all data analyses|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5545845	28784084	SB	2	conceived and designed the study|wrote the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5545845	28784084	SB	2	conceived and designed the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
1851097	17460761	AP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1851097	17460761	AP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1851097	17460761	AP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1851097	17460761	CL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1851097	17460761	CL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1851097	17460761	CL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1851097	17460761	DS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1851097	17460761	DS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1851097	17460761	DS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1851097	17460761	DS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1851097	17460761	GL	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1851097	17460761	GL	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1851097	17460761	JP	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1851097	17460761	JP	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1851097	17460761	PR	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1851097	17460761	PR	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1851097	17460761	RB	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1851097	17460761	RB	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1851097	17460761	TN	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1851097	17460761	TN	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5110135	27867470	MY	2	critically revised and wrote the manuscript	critically revised and wrote the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5110135	27867470	ST	2	collected and analyzed the data	collected and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5110135	27867470	TH	2	collected, analyzed and reviewed the data and wrote the first draft of the manuscript	collected, analyzed and reviewed the data and wrote the first draft of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
2660282	19284589	CD	2	developed the study hypothesis, research design, data collection, analysis, and manuscript preparation	developed the study hypothesis, research design, data collection, analysis, and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
2660282	19284589	HB	2	developed the study hypothesis, research design, data collection, analysis, and manuscript preparation	developed the study hypothesis, research design, data collection, analysis, and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
2660282	19284589	JL	2	participated in subject screening, interviews and manuscript preparation	participated in subject screening, interviews and manuscript preparation	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
2660282	19284589	PH	2	participated in research design, data interpretation and manuscript preparation	participated in research design, data interpretation and manuscript preparation	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
2660282	19284589	RB	2	participated in blood collection technique, analysis and interpretation of results	participated in blood collection technique, analysis and interpretation of results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5153393	27957722	HY	2	drafted the article	drafted the article	Wrote the paper	Writing - Original Draft	YES
5153393	27957722	KH	2	drafted the article	drafted the article	Wrote the paper	Writing - Original Draft	YES
5153393	27957722	KN	2	participated in the collection and assembly of the data	participated in the collection and assembly of the data	Performed the experiments	Investigation	YES
5153393	27957722	NK	2	carried out the data analysis and interpretation	carried out the data analysis and interpretation	Analyzed the data	Formal analysis	YES
5153393	27957722	NT	2	conceived of and made the study design	conceived of and made the study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5153393	27957722	NU	2	conceived of and made the study design|carried out the data analysis and interpretation|participated in the collection and assembly of the data|drafted the article|did the critical revision of the article for important intellectual content	conceived of and made the study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5153393	27957722	NU	2	conceived of and made the study design|carried out the data analysis and interpretation|participated in the collection and assembly of the data|drafted the article|did the critical revision of the article for important intellectual content	carried out the data analysis and interpretation	Analyzed the data	Formal analysis	YES
5153393	27957722	NU	2	conceived of and made the study design|carried out the data analysis and interpretation|participated in the collection and assembly of the data|drafted the article|did the critical revision of the article for important intellectual content	participated in the collection and assembly of the data	Performed the experiments	Investigation	YES
5153393	27957722	NU	2	conceived of and made the study design|carried out the data analysis and interpretation|participated in the collection and assembly of the data|drafted the article|did the critical revision of the article for important intellectual content	drafted the article	Wrote the paper	Writing - Original Draft	YES
5153393	27957722	NU	2	conceived of and made the study design|carried out the data analysis and interpretation|participated in the collection and assembly of the data|drafted the article|did the critical revision of the article for important intellectual content	did the critical revision of the article for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5153393	27957722	SZ	2	conceived of and made the study design|participated in the collection and assembly of the data|drafted the article	conceived of and made the study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5153393	27957722	SZ	2	conceived of and made the study design|participated in the collection and assembly of the data|drafted the article	participated in the collection and assembly of the data	Performed the experiments	Investigation	YES
5153393	27957722	SZ	2	conceived of and made the study design|participated in the collection and assembly of the data|drafted the article	drafted the article	Wrote the paper	Writing - Original Draft	YES
5153393	27957722	WY	2	participated in the collection and assembly of the data	participated in the collection and assembly of the data	Performed the experiments	Investigation	YES
5153393	27957722	YK	2	conceived of and made the study design|conceived of and made the study design|drafted the article|did the critical revision of the article for important intellectual content|made the final approval of the article	conceived of and made the study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5153393	27957722	YK	2	conceived of and made the study design|conceived of and made the study design|drafted the article|did the critical revision of the article for important intellectual content|made the final approval of the article	conceived of and made the study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5153393	27957722	YK	2	conceived of and made the study design|conceived of and made the study design|drafted the article|did the critical revision of the article for important intellectual content|made the final approval of the article	drafted the article	Wrote the paper	Writing - Original Draft	YES
5153393	27957722	YK	2	conceived of and made the study design|conceived of and made the study design|drafted the article|did the critical revision of the article for important intellectual content|made the final approval of the article	did the critical revision of the article for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5153393	27957722	YK	2	conceived of and made the study design|conceived of and made the study design|drafted the article|did the critical revision of the article for important intellectual content|made the final approval of the article	made the final approval of the article	-	-	NO
5153393	27957722	YS	2	participated in the collection and assembly of the data	participated in the collection and assembly of the data	Performed the experiments	Investigation	YES
4412265	25647747	BK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412265	25647747	BK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412265	25647747	BK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412265	25647747	BK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412265	25647747	BK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5682035	29163622	All authors	2	read and approved the manuscript	read and approved the manuscript	-	-	NO
5682035	29163622	F-FL	2	conducted experiments|analyzed data	conducted experiments	Performed the experiments	Investigation	YES
5682035	29163622	F-FL	2	conducted experiments|analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5682035	29163622	JX	2	conducted experiments	conducted experiments	Performed the experiments	Investigation	YES
5682035	29163622	S-XX	2	conceived and designed research|revised the manuscript	conceived and designed research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5682035	29163622	S-XX	2	conceived and designed research|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5682035	29163622	S-YC	2	conceived and designed research	conceived and designed research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5682035	29163622	X-CM	2	contributed new reagents and analytical tools	contributed new reagents and analytical tools	Contributed reagents/materials/analysis tools	Resources	YES
5682035	29163622	X-PL	2	conceived and designed research|conducted experiments|analyzed data	conceived and designed research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5682035	29163622	X-PL	2	conceived and designed research|conducted experiments|analyzed data	conducted experiments	Performed the experiments	Investigation	YES
5682035	29163622	X-PL	2	conceived and designed research|conducted experiments|analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5682035	29163622	Z-MZ	2	contributed new reagents and analytical tools	contributed new reagents and analytical tools	Contributed reagents/materials/analysis tools	Resources	YES
1851098	17460764	AI	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1851098	17460764	AI	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1851098	17460764	AI	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1851098	17460764	NF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1851098	17460764	NF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1851098	17460764	NF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1851098	17460764	NF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1851098	17460764	SH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1851098	17460764	SH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1851098	17460764	SH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5110136	27867483	LKX	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5110136	27867483	SHY	2	proof-read the manuscript	proof-read the manuscript	-	-	NO
5545864	28784091	CZ	PLoS52	analyzed the transcriptome data|analyzed the sequence data	analyzed the transcriptome data	Analyzed the data	Formal analysis	YES
5545864	28784091	CZ	PLoS52	analyzed the transcriptome data|analyzed the sequence data	analyzed the sequence data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5545864	28784091	GL	PLoS52	performed the experiments|analyzed the transcriptome data|analyzed the sequence data|drafted the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5545864	28784091	GL	PLoS52	performed the experiments|analyzed the transcriptome data|analyzed the sequence data|drafted the manuscript	analyzed the transcriptome data	Analyzed the data	Formal analysis	YES
5545864	28784091	GL	PLoS52	performed the experiments|analyzed the transcriptome data|analyzed the sequence data|drafted the manuscript	analyzed the sequence data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5545864	28784091	GL	PLoS52	performed the experiments|analyzed the transcriptome data|analyzed the sequence data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5545864	28784091	GS	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5545864	28784091	HZ	PLoS52	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5545864	28784091	SS	PLoS52	analyzed the transcriptome data|analyzed the sequence data	analyzed the transcriptome data	Analyzed the data	Formal analysis	YES
5545864	28784091	SS	PLoS52	analyzed the transcriptome data|analyzed the sequence data	analyzed the sequence data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5545864	28784091	TX	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5545864	28784091	XG	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5545864	28784091	XY	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
4412395	25919297	BY	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4412395	25919297	BY	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412395	25919297	HDK	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412395	25919297	HDK	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412395	25919297	HDK	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412395	25919297	HDK	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412395	25919297	HS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4412395	25919297	HS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4412395	25919297	SK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412395	25919297	SK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412395	25919297	SK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412395	25919297	YF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412395	25919297	YF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412395	25919297	YF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412395	25919297	YF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2674410	19341458	EG	2	was responsible for data input and analysis as well as manuscript preparation	was responsible for data input and analysis as well as manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
2674410	19341458	IO	2	carried out literature review, data collection and input	carried out literature review, data collection and input	Performed the experiments	Formal analysis|Investigation	YES
2674410	19341458	JH	2	was responsible for data analysis and manuscript preparation	was responsible for data analysis and manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
2674410	19341458	PJ	2	was responsible for study design, data collection, statistical analysis, and manuscript preparation	was responsible for study design, data collection, statistical analysis, and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
2674410	19341458	WB	2	carried out data collection and input	carried out data collection and input	Performed the experiments	Investigation	YES
5682037	29163623	B-hL	PLoS52	conceived and designed the research|discussed the results|wrote the paper	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5682037	29163623	B-hL	PLoS52	conceived and designed the research|discussed the results|wrote the paper	discussed the results	-	-	NO
5682037	29163623	B-hL	PLoS52	conceived and designed the research|discussed the results|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5682037	29163623	D-JY	PLoS52	conceived and designed the research|discussed the results	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5682037	29163623	D-JY	PLoS52	conceived and designed the research|discussed the results	discussed the results	-	-	NO
5682037	29163623	J-KZ	PLoS52	conceived and designed the research|discussed the results	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5682037	29163623	J-KZ	PLoS52	conceived and designed the research|discussed the results	discussed the results	-	-	NO
5682037	29163623	JP	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5682037	29163623	S-iY	PLoS52	performed the experiments|discussed the results|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5682037	29163623	S-iY	PLoS52	performed the experiments|discussed the results|wrote the paper	discussed the results	-	-	NO
5682037	29163623	S-iY	PLoS52	performed the experiments|discussed the results|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5682037	29163623	SC	PLoS52	performed the experiments|discussed the results|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5682037	29163623	SC	PLoS52	performed the experiments|discussed the results|wrote the paper	discussed the results	-	-	NO
5682037	29163623	SC	PLoS52	performed the experiments|discussed the results|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5682037	29163623	YM	PLoS52	performed the experiments|discussed the results	performed the experiments	Performed the experiments	Investigation	YES
5682037	29163623	YM	PLoS52	performed the experiments|discussed the results	discussed the results	-	-	NO
4052666	24949278	AVP	2	conceived of the study, and participated in its design and coordination and helped to draft the manuscript	conceived of the study, and participated in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
4052666	24949278	DJS	2	carried out the molecular biology studies	carried out the molecular biology studies	Performed the experiments	Investigation	YES
4052666	24949278	RL	2	designed and carried out the cultivations, fermentations and mortality tests, analyzed the data and wrote the manuscript	designed and carried out the cultivations, fermentations and mortality tests, analyzed the data and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5110137	27867488	JLS	2	designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
5110137	27867488	LRQ	2	designed the research|analyzed the data and prepared the typescript	designed the research	Conceived and designed the experiments	Methodology	YES
5110137	27867488	LRQ	2	designed the research|analyzed the data and prepared the typescript	analyzed the data and prepared the typescript	Analyzed the data	Formal analysis	YES
5153397	27957723	CBY	2	performed the analyses of synthesis results|contributed to the design of the study and writing process of the manuscript and performed the metabolite assay and analysis of the results	performed the analyses of synthesis results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5153397	27957723	CBY	2	performed the analyses of synthesis results|contributed to the design of the study and writing process of the manuscript and performed the metabolite assay and analysis of the results	contributed to the design of the study and writing process of the manuscript and performed the metabolite assay and analysis of the results	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5153397	27957723	KM	2	contributed to the design of the study, acquired, analyzed, and interpreted the animal studies and studies with human pancreas, and wrote the manuscript	contributed to the design of the study, acquired, analyzed, and interpreted the animal studies and studies with human pancreas, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5153397	27957723	MK	2	contributed to the studies performed with pigs	contributed to the studies performed with pigs	Performed the experiments	Investigation	YES
5153397	27957723	OS	2	coordinated the radiochemistry and tracer production|contributed to the design and coordination of the study, revised the manuscript, and gave final approval for the published version	coordinated the radiochemistry and tracer production	-	Project administration	YES
5153397	27957723	OS	2	coordinated the radiochemistry and tracer production|contributed to the design and coordination of the study, revised the manuscript, and gave final approval for the published version	contributed to the design and coordination of the study, revised the manuscript, and gave final approval for the published version	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Review & Editing	YES
5153397	27957723	PL	2	performed the analyses of synthesis results	performed the analyses of synthesis results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5153397	27957723	PN	2	contributed to the design and coordination of the study, revised the manuscript, and gave final approval for the published version	contributed to the design and coordination of the study, revised the manuscript, and gave final approval for the published version	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Review & Editing	YES
5153397	27957723	SK	2	performed the surgeries and collection of samples of human pancreas	performed the surgeries and collection of samples of human pancreas	Performed the experiments	Investigation	YES
5153397	27957723	TT	2	performed the dosimetry calculations	performed the dosimetry calculations	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
1851099	17460756	AN	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1851099	17460756	CF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1851099	17460756	CF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1851099	17460756	CF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1851099	17460756	GS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1851099	17460756	GS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1851099	17460756	GS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1851099	17460756	GS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1851099	17460756	JK	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1851099	17460756	JR	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1851099	17460756	JR	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1851099	17460756	JR	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1851099	17460756	MK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1851099	17460756	MK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1851099	17460756	MK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1851099	17460756	PC	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1851099	17460756	PC	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1851099	17460756	PL	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1851099	17460756	PL	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1851099	17460756	SP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1851099	17460756	SP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1851099	17460756	SP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1851099	17460756	VG	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1851099	17460756	VG	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1851099	17460756	VG	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1851099	17460756	VG	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1851099	17460756	YC	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1851099	17460756	YC	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1851099	17460756	YC	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412397	25919452	CC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412397	25919452	CC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412397	25919452	CC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412397	25919452	KZ	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4412397	25919452	KZ	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412397	25919452	LL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4412397	25919452	LL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412397	25919452	YFS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4412397	25919452	YFS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4412397	25919452	YX	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412397	25919452	ZGS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412397	25919452	ZGS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5547472	28784083	AP	2	provided the genetic material and supervised the growing of plant material|edited the manuscript	provided the genetic material and supervised the growing of plant material	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources|Supervision	YES
5547472	28784083	AP	2	provided the genetic material and supervised the growing of plant material|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5547472	28784083	DE	2	performed the transcriptome assembly|developed methodology for snp calling and data analyses|edited the manuscript	performed the transcriptome assembly	Performed the experiments	Investigation	YES
5547472	28784083	DE	2	performed the transcriptome assembly|developed methodology for snp calling and data analyses|edited the manuscript	developed methodology for snp calling and data analyses	Performed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5547472	28784083	DE	2	performed the transcriptome assembly|developed methodology for snp calling and data analyses|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5547472	28784083	GG	2	performed rna and dna extractions, performed the data analyses and wrote the manuscript|developed methodology for snp calling and data analyses	performed rna and dna extractions, performed the data analyses and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5547472	28784083	GG	2	performed rna and dna extractions, performed the data analyses and wrote the manuscript|developed methodology for snp calling and data analyses	developed methodology for snp calling and data analyses	Performed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5547472	28784083	PA	2	developed methodology for snp calling and data analyses|edited the manuscript	developed methodology for snp calling and data analyses	Performed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5547472	28784083	PA	2	developed methodology for snp calling and data analyses|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5547472	28784083	REV	2	edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5547472	28784083	RGFV	2	edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5547472	28784083	SNP	2	dosage scoring	dosage scoring	-	-	NO
5110138	27867484	JZ	2	is the corresponding author, and participated in conceiving and revising of the manuscript	is the corresponding author, and participated in conceiving and revising of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5110138	27867484	LH	2	participated in the manuscript drafting and editing, as well as gathering the references	participated in the manuscript drafting and editing, as well as gathering the references	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5110138	27867484	RC	2	conceived, collected the information/figures/references, and drafted the manuscript	conceived, collected the information/figures/references, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Visualization|Writing - Original Draft	YES
2691397	19442266	BW	2	handled blood, assisted during trials, performed glycogen assay	handled blood, assisted during trials, performed glycogen assay	Performed the experiments	Investigation	YES
2691397	19442266	DH	2	performed western blots	performed western blots	Performed the experiments	Investigation	YES
2691397	19442266	JI	2	defined the protocol, wrote and acquired grant, performed muscle biopsies, directed muscle tissue assays, reviewed and wrote portions of document	defined the protocol, wrote and acquired grant, performed muscle biopsies, directed muscle tissue assays, reviewed and wrote portions of document	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Supervision|Writing - Original Draft	YES
2691397	19442266	LK	2	recruited subjects, performed vo 2max tests, coordinated trial personnel, performed lactate assay, performed all statistical analysis and wrote document	recruited subjects, performed vo 2max tests, coordinated trial personnel, performed lactate assay, performed all statistical analysis and wrote document	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Project administration|Writing - Original Draft	YES
2691397	19442266	YHL	2	performed western blots	performed western blots	Performed the experiments	Investigation	YES
4581573	26448753	Ilia Atanelishvili	2	helped to draw the figures	helped to draw the figures	-	Visualization	YES
4581573	26448753	Ricardo Moreno Rodriguez	2	helped to draw the figures	helped to draw the figures	-	Visualization	YES
4581573	26448753	Roger R. Markwald	2	edited the final paper	edited the final paper	Wrote the paper	Writing - Review & Editing	YES
4581573	26448753	Shibnath Ghatak	2	wrote the review	wrote the review	Wrote the paper	Writing - Original Draft	YES
4581573	26448753	Suniti Misra	2	wrote the review	wrote the review	Wrote the paper	Writing - Original Draft	YES
4581573	26448753	Vincent C. Hascall	2	reviewed the draft and final paper	reviewed the draft and final paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5682324	29167680	AN	4	The review was finally edited and submitted by	The review was finally edited and submitted by	Wrote the paper	Writing - Review & Editing	YES
5177600	28004357	B. All	2	authors participated in drafting and revising this paper	authors participated in drafting and revising this paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
1851986	17460762	CH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1851986	17460762	CH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1851986	17460762	CH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1851986	17460762	CH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1851986	17460762	CH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1851986	17460762	CL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1851986	17460762	CL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1851986	17460762	CL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1851986	17460762	FK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1851986	17460762	JL	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1851986	17460762	JL	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1851986	17460762	KF	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412398	25919591	HG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4412398	25919591	HT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412398	25919591	HT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412398	25919591	HT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412398	25919591	HT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412398	25919591	JL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4412398	25919591	QX	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412398	25919591	QX	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412398	25919591	SZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4412398	25919591	WY	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4412398	25919591	X. Xiang	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4412398	25919591	X. Xu	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5110139	27867482	KJL	2	participated in the overall design of the review and obtained partial funding	participated in the overall design of the review and obtained partial funding	Conceived and designed the experiments	Funding acquisition	YES
5110139	27867482	SHS	2	reviewed the nbo studies in stroke, wrote up the manuscript	reviewed the nbo studies in stroke, wrote up the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5110139	27867482	XMJ	2	reviewed the nbo studies in clinic and edited the overall manuscript	reviewed the nbo studies in clinic and edited the overall manuscript	Wrote the paper	Writing - Review & Editing	YES
5110139	27867482	YML	2	improved the structure	improved the structure	-	-	NO
5110139	27867482	ZFQ	2	improved the structure	improved the structure	-	-	NO
5547479	28784089	AA	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5547479	28784089	AA	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5547479	28784089	BK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5547479	28784089	BK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
5547479	28784089	BK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5547479	28784089	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5547479	28784089	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
5547479	28784089	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5547479	28784089	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5547479	28784089	RA	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
5547479	28784089	RA	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5547479	28784089	RA	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5547479	28784089	SL	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5547479	28784089	TL	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5547479	28784089	TL	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5547479	28784089	YP	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2694142	19480650	CPE	2	designed this study and was responsible for all data analysis and the primary writing of this manuscript	designed this study and was responsible for all data analysis and the primary writing of this manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
2694142	19480650	CRM	2	assisted with data management, analysis and manuscript preparation	assisted with data management, analysis and manuscript preparation	Analyzed the data|Wrote the paper	Data curation|Formal analysis|Writing - Original Draft	YES
2694142	19480650	JAB	2	were responsible for the analysis of all fatty acids	were responsible for the analysis of all fatty acids	-	-	NO
2694142	19480650	MKH	2	prepared all intervention meals and assisted with the writing of this manuscript	prepared all intervention meals and assisted with the writing of this manuscript	Wrote the paper	Writing - Original Draft	YES
2694142	19480650	MM	2	assisted in meal preparation and was responsible for the recruiting and scheduling of study participants	assisted in meal preparation and was responsible for the recruiting and scheduling of study participants	Performed the experiments	Investigation	YES
2694142	19480650	RMD	2	were responsible for the analysis of all fatty acids	were responsible for the analysis of all fatty acids	-	-	NO
2694142	19480650	TSC	2	was the medical director for this trial and assisted in manuscript preparation	was the medical director for this trial and assisted in manuscript preparation	Wrote the paper	Writing - Original Draft	YES
4052670	24949260	KM	2	reviewed the data and the manuscript	reviewed the data and the manuscript	Wrote the paper	Writing - Review & Editing	YES
4052670	24949260	NH	2	designed the study in icellis nano bioreactor	designed the study in icellis nano bioreactor	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4052670	24949260	SD	2	designed the study in icellis nano bioreactor	designed the study in icellis nano bioreactor	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4052670	24949260	SRM	2	performed the chromatography	performed the chromatography	Performed the experiments	Investigation	YES
5682329	29167675	CJ	2	designed and supervised this study	designed and supervised this study	Conceived and designed the experiments	Methodology|Supervision	YES
5682329	29167675	XW	2	designed and supervised this study|conducted the experiments, performed data interpretation, and drafted the manuscript	designed and supervised this study	Conceived and designed the experiments	Methodology|Supervision	YES
5682329	29167675	XW	2	designed and supervised this study|conducted the experiments, performed data interpretation, and drafted the manuscript	conducted the experiments, performed data interpretation, and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5682329	29167675	YL	2	helped revise the manuscript in grammar	helped revise the manuscript in grammar	Wrote the paper	Writing - Review & Editing	YES
1851987	17460754	DT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1851987	17460754	DT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1851987	17460754	DT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1851987	17460754	DT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1851987	17460754	DT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1851987	17460754	ES	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1851987	17460754	ES	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1851987	17460754	GG	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1851987	17460754	GG	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1851987	17460754	WS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1851987	17460754	WS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1851987	17460754	WS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412401	25919005	AG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4412401	25919005	AM	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4412401	25919005	AM	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4412401	25919005	AP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4412401	25919005	BM	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412401	25919005	BM	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412401	25919005	BdB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4412401	25919005	FB	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4412401	25919005	FB	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4412401	25919005	JLM	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412401	25919005	JLM	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412401	25919005	JPG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412401	25919005	JPG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412401	25919005	JPG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412401	25919005	KvB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412401	25919005	KvB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412401	25919005	KvB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412401	25919005	KvB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412401	25919005	LC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4412401	25919005	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412401	25919005	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412401	25919005	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412401	25919005	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412401	25919005	SH	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4412401	25919005	SH	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412401	25919005	VAG	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4412401	25919005	VAG	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5547493	28784086	BW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5547493	28784086	BW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
5547493	28784086	BW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5547493	28784086	BW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5547493	28784086	BW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5547493	28784086	GW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5547493	28784086	GW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5547493	28784086	GW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5547493	28784086	YL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5547493	28784086	YL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5547493	28784086	YL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5547493	28784086	YL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5215993	28058660	All authors	2	critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5215993	28058660	MNB	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
2697134	19490606	AW	2	assisted in data collection	assisted in data collection	Performed the experiments	Investigation	YES
2697134	19490606	ER	2	assisted in data collection	assisted in data collection	Performed the experiments	Investigation	YES
2697134	19490606	MC	2	was the study coordinator and was involved in data analysis and manuscript preparation	was the study coordinator and was involved in data analysis and manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Project administration|Writing - Original Draft	YES
2697134	19490606	PC	2	assisted in data collection, research design and obtaining grant funding	assisted in data collection, research design and obtaining grant funding	Conceived and designed the experiments|Performed the experiments	Funding acquisition|Investigation	YES
2697134	19490606	PI	2	of the study	of the study	-	-	NO
5110141	27867481	GXD	2	provided assistance with data analysis and presentation of the data and preparation of paper publication	provided assistance with data analysis and presentation of the data and preparation of paper publication	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5110141	27867481	HGH	2	was responsible for the most aspects of the study including the data collection, data analysis and manuscript writing	was responsible for the most aspects of the study including the data collection, data analysis and manuscript writing	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5110141	27867481	HS	2	was responsible for analyzing and overviews and interpretation of the results	was responsible for analyzing and overviews and interpretation of the results	Analyzed the data	Formal analysis	YES
5110141	27867481	NK	2	was responsible for assisting in the design of the in vivo animal experiments and data analysis and preparation of paper publication	was responsible for assisting in the design of the in vivo animal experiments and data analysis and preparation of paper publication	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5110141	27867481	SH	2	provided assistance with the presentation of the histological results	provided assistance with the presentation of the histological results	Performed the experiments	Investigation	YES
1851988	17460763	FI	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1851988	17460763	FI	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1851988	17460763	MR	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1851988	17460763	WL	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1851988	17460763	WL	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1851988	17460763	WZ	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1851988	17460763	WZ	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5682339	29167678	All	2	authors read and approved the final manuscript	authors read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5682339	29167678	D-HK	2	participated in qpcr analysis, y2h assay and arabidopsis transformation	participated in qpcr analysis, y2h assay and arabidopsis transformation	Performed the experiments	Investigation	YES
5682339	29167678	J-YL	2	carried out the transient assay of tobacco leaves	carried out the transient assay of tobacco leaves	Performed the experiments	Investigation	YES
5682339	29167678	JK	2	analyzed the anthocyanins	analyzed the anthocyanins	Analyzed the data	Formal analysis	YES
5682339	29167678	S-HL	2	designed and performed the experiments and prepared the figures|authors read and approved the final manuscript	designed and performed the experiments and prepared the figures	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Visualization	YES
5682339	29167678	S-HL	2	designed and performed the experiments and prepared the figures|authors read and approved the final manuscript	authors read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5110142	27867487	AM	2	modified the language	modified the language	-	-	NO
5110142	27867487	JLH	2	write the paper	write the paper	Wrote the paper	Writing - Original Draft	YES
5110142	27867487	QH	2	modified the language	modified the language	-	-	NO
5110142	27867487	XJS	2	gave suggestions	gave suggestions	-	-	NO
5110142	27867487	ZHY	2	gave suggestions	gave suggestions	-	-	NO
1851989	17460765	AR	PLoS5	Analyzed the data|Assisted in writing the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1851989	17460765	AR	PLoS5	Analyzed the data|Assisted in writing the paper	Assisted in writing the paper	Wrote the paper	Writing - Original Draft	YES
1851989	17460765	CR	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1851989	17460765	DB	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1851989	17460765	DB	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1851989	17460765	IR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1851989	17460765	IR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1851989	17460765	IR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1851989	17460765	IR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1851989	17460765	JI	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1851989	17460765	JI	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1851989	17460765	JI	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1851989	17460765	JR	PLoS5	Analyzed the data|Assisted in writing the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1851989	17460765	JR	PLoS5	Analyzed the data|Assisted in writing the paper	Assisted in writing the paper	Wrote the paper	Writing - Original Draft	YES
1851989	17460765	MM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1851989	17460765	MM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1851989	17460765	YK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Assisted in writing the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1851989	17460765	YK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Assisted in writing the paper	Performed the experiments	Performed the experiments	Investigation	YES
1851989	17460765	YK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Assisted in writing the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1851989	17460765	YK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Assisted in writing the paper	Assisted in writing the paper	Wrote the paper	Writing - Original Draft	YES
4575996	26436088	Ming-Zhe Zhao	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
4575996	26436088	Wen Xue	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
4575996	26436088	Zhong Zheng	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
4575996	26436088	Zi-Xun Yan	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
5547501	28784092	BZ	2	participated in the design and in drafting the manuscript	participated in the design and in drafting the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
5547501	28784092	CZ	2	conceived, designed, implemented, tested and validated the workflow, and drafted the manuscript	conceived, designed, implemented, tested and validated the workflow, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Validation|Writing - Original Draft	YES
5547501	28784092	LL	2	participated in the design and in drafting the manuscript	participated in the design and in drafting the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
5547501	28784092	SZ	2	conceived, designed, implemented, tested and validated the workflow, and drafted the manuscript	conceived, designed, implemented, tested and validated the workflow, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Validation|Writing - Original Draft	YES
5682393	29167679	All of the authors	PLoS52	finally approved the manuscript	finally approved the manuscript	-	-	NO
5682393	29167679	F-LC	PLoS52	contributed materials/analysis tools	contributed materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5682393	29167679	KS	PLoS52	performed the experiments|contributed materials/analysis tools|wrote the manuscript|revised the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5682393	29167679	KS	PLoS52	performed the experiments|contributed materials/analysis tools|wrote the manuscript|revised the manuscript	contributed materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5682393	29167679	KS	PLoS52	performed the experiments|contributed materials/analysis tools|wrote the manuscript|revised the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5682393	29167679	KS	PLoS52	performed the experiments|contributed materials/analysis tools|wrote the manuscript|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5682393	29167679	UZ	PLoS52	contributed materials/analysis tools	contributed materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5682393	29167679	YJ	PLoS52	performed the experiments|contributed materials/analysis tools|revised the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5682393	29167679	YJ	PLoS52	performed the experiments|contributed materials/analysis tools|revised the manuscript	contributed materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5682393	29167679	YJ	PLoS52	performed the experiments|contributed materials/analysis tools|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5682393	29167679	Z-HL	PLoS52	designed and conceived the study|contributed materials/analysis tools|wrote the manuscript|revised the manuscript	designed and conceived the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5682393	29167679	Z-HL	PLoS52	designed and conceived the study|contributed materials/analysis tools|wrote the manuscript|revised the manuscript	contributed materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5682393	29167679	Z-HL	PLoS52	designed and conceived the study|contributed materials/analysis tools|wrote the manuscript|revised the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5682393	29167679	Z-HL	PLoS52	designed and conceived the study|contributed materials/analysis tools|wrote the manuscript|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
2698827	19500355	BBS	2	participated in the design of the study, performed the statistical analysis, and drafted the manuscript	participated in the design of the study, performed the statistical analysis, and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
2698827	19500355	ES	2	participated in the coordination of the study	participated in the coordination of the study	-	Project administration	YES
2698827	19500355	JKU	2	conceived of the study, and participated in its design and coordination and helped to draft the manuscript	conceived of the study, and participated in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
2698827	19500355	VJS	2	participated in the statistical analysis and in the drafting of the manuscript	participated in the statistical analysis and in the drafting of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5215994	28058659	All authors	2	discussed the results and implications, commented on the manuscript at all stages, and critically revised the manuscript	discussed the results and implications, commented on the manuscript at all stages, and critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5215994	28058659	HB	2	contributed to the conception and design|contributed to the acquisition of data|are responsible for the final approval of the manuscript	contributed to the conception and design	Conceived and designed the experiments	Conceptualization	YES
5215994	28058659	HB	2	contributed to the conception and design|contributed to the acquisition of data|are responsible for the final approval of the manuscript	contributed to the acquisition of data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5215994	28058659	HB	2	contributed to the conception and design|contributed to the acquisition of data|are responsible for the final approval of the manuscript	are responsible for the final approval of the manuscript	-	-	NO
5215994	28058659	HDZ	2	contributed to the conception and design|contributed to the acquisition of data|contributed to the analysis/interpretation of data|participated in the drafting the manuscript|are responsible for the final approval of the manuscript	contributed to the conception and design	Conceived and designed the experiments	Conceptualization	YES
5215994	28058659	HDZ	2	contributed to the conception and design|contributed to the acquisition of data|contributed to the analysis/interpretation of data|participated in the drafting the manuscript|are responsible for the final approval of the manuscript	contributed to the acquisition of data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5215994	28058659	HDZ	2	contributed to the conception and design|contributed to the acquisition of data|contributed to the analysis/interpretation of data|participated in the drafting the manuscript|are responsible for the final approval of the manuscript	contributed to the analysis/interpretation of data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5215994	28058659	HDZ	2	contributed to the conception and design|contributed to the acquisition of data|contributed to the analysis/interpretation of data|participated in the drafting the manuscript|are responsible for the final approval of the manuscript	participated in the drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
5215994	28058659	HDZ	2	contributed to the conception and design|contributed to the acquisition of data|contributed to the analysis/interpretation of data|participated in the drafting the manuscript|are responsible for the final approval of the manuscript	are responsible for the final approval of the manuscript	-	-	NO
5215994	28058659	JAE	2	contributed to the analysis/interpretation of data|are responsible for the final approval of the manuscript	contributed to the analysis/interpretation of data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5215994	28058659	JAE	2	contributed to the analysis/interpretation of data|are responsible for the final approval of the manuscript	are responsible for the final approval of the manuscript	-	-	NO
5215994	28058659	JBM	2	contributed to the analysis/interpretation of data|contributed to the statistical analysis|are responsible for the final approval of the manuscript	contributed to the analysis/interpretation of data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5215994	28058659	JBM	2	contributed to the analysis/interpretation of data|contributed to the statistical analysis|are responsible for the final approval of the manuscript	contributed to the statistical analysis	Analyzed the data	Formal analysis	YES
5215994	28058659	JBM	2	contributed to the analysis/interpretation of data|contributed to the statistical analysis|are responsible for the final approval of the manuscript	are responsible for the final approval of the manuscript	-	-	NO
5215994	28058659	JF	2	contributed to the analysis/interpretation of data|are responsible for the final approval of the manuscript	contributed to the analysis/interpretation of data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5215994	28058659	JF	2	contributed to the analysis/interpretation of data|are responsible for the final approval of the manuscript	are responsible for the final approval of the manuscript	-	-	NO
5215994	28058659	LJP	2	contributed to the conception and design|contributed to the acquisition of data|contributed to the analysis/interpretation of data|are responsible for the final approval of the manuscript	contributed to the conception and design	Conceived and designed the experiments	Conceptualization	YES
5215994	28058659	LJP	2	contributed to the conception and design|contributed to the acquisition of data|contributed to the analysis/interpretation of data|are responsible for the final approval of the manuscript	contributed to the acquisition of data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5215994	28058659	LJP	2	contributed to the conception and design|contributed to the acquisition of data|contributed to the analysis/interpretation of data|are responsible for the final approval of the manuscript	contributed to the analysis/interpretation of data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5215994	28058659	LJP	2	contributed to the conception and design|contributed to the acquisition of data|contributed to the analysis/interpretation of data|are responsible for the final approval of the manuscript	are responsible for the final approval of the manuscript	-	-	NO
5215994	28058659	RA	2	contributed to the analysis/interpretation of data|are responsible for the final approval of the manuscript	contributed to the analysis/interpretation of data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5215994	28058659	RA	2	contributed to the analysis/interpretation of data|are responsible for the final approval of the manuscript	are responsible for the final approval of the manuscript	-	-	NO
5110143	27867486	JEB	PLoS52	designed the experiments, analyzed data, and wrote the manuscript	designed the experiments, analyzed data, and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5110143	27867486	JHA	PLoS52	designed the experiments, analyzed data, and wrote the manuscript	designed the experiments, analyzed data, and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5110143	27867486	JJR	PLoS52	designed the experiments, analyzed data, and wrote the manuscript	designed the experiments, analyzed data, and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5110143	27867486	LC	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5110143	27867486	NV	PLoS52	designed the experiments, analyzed data, and wrote the manuscript	designed the experiments, analyzed data, and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5110143	27867486	SB	PLoS52	designed the experiments, analyzed data, and wrote the manuscript	designed the experiments, analyzed data, and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4412404	25919316	RN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412404	25919316	RN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412404	25919316	RN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412404	25919316	RN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412404	25919316	RN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412404	25919316	SS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412404	25919316	SS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1851990	17476321	AI	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1851990	17476321	AY	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1851990	17476321	AY	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1851990	17476321	ET	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1851990	17476321	JI	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1851990	17476321	JI	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1851990	17476321	JI	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1851990	17476321	JJ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1851990	17476321	KD	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1851990	17476321	LS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1851990	17476321	LS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1851990	17476321	ME	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1851990	17476321	ME	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1851990	17476321	ME	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1851990	17476321	ME	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1851990	17476321	PY	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1851990	17476321	PY	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1851990	17476321	RH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1851990	17476321	TH	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1851990	17476321	VG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5110144	27867480	All authors	PLoS52	were involved in experimental work and data acquisition, literature search and revision, and approved the final version of the paper	were involved in experimental work and data acquisition, literature search and revision, and approved the final version of the paper	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
5110144	27867480	JHB	PLoS52	were responsible for study concept and statistical analysis|wrote the paper	were responsible for study concept and statistical analysis	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
5110144	27867480	JHB	PLoS52	were responsible for study concept and statistical analysis|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5110144	27867480	MH	PLoS52	were responsible for study concept and statistical analysis	were responsible for study concept and statistical analysis	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
4052683	24949277	MA	4	Experimental design and the subsequent manuscript were reviewed by	Experimental design and the subsequent manuscript were reviewed by	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
4052683	24949277	PTA	4	work and writing of the manuscript were carried out by	work and writing of the manuscript were carried out by	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
1852331	17476326	JT	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1852331	17476326	JT	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1852331	17476326	LZ	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1852331	17476326	RO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1852331	17476326	RO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1852331	17476326	RO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1852331	17476326	RO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1852331	17476326	SS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1852331	17476326	SS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5547544	28784085	GN	2	designed the methodology and performed data analysis	designed the methodology and performed data analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5547544	28784085	JO	2	conceptualized the study|provided the biological material	conceptualized the study	Conceived and designed the experiments	Conceptualization	YES
5547544	28784085	JO	2	conceptualized the study|provided the biological material	provided the biological material	Contributed reagents/materials/analysis tools	Resources	YES
5547544	28784085	MPM	2	designed the methodology and performed data analysis	designed the methodology and performed data analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5547544	28784085	MS	2	conceptualized the study|designed the methodology and performed data analysis	conceptualized the study	Conceived and designed the experiments	Conceptualization	YES
5547544	28784085	MS	2	conceptualized the study|designed the methodology and performed data analysis	designed the methodology and performed data analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5547544	28784085	TR	2	conceptualized the study	conceptualized the study	Conceived and designed the experiments	Conceptualization	YES
5682563	29167676	JH	2	conceived the idea of the experiment|provided the technical guidance and editing support	conceived the idea of the experiment	Conceived and designed the experiments	Conceptualization	YES
5682563	29167676	JH	2	conceived the idea of the experiment|provided the technical guidance and editing support	provided the technical guidance and editing support	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Review & Editing	YES
5682563	29167676	KC	2	provided the technical guidance and editing support	provided the technical guidance and editing support	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Review & Editing	YES
5682563	29167676	LN	2	provided the technical guidance and editing support	provided the technical guidance and editing support	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Review & Editing	YES
5682563	29167676	SF	2	gathered the literature and contributed in arranging the data for different attributes|provided the technical guidance and editing support	gathered the literature and contributed in arranging the data for different attributes	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5682563	29167676	SF	2	gathered the literature and contributed in arranging the data for different attributes|provided the technical guidance and editing support	provided the technical guidance and editing support	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Review & Editing	YES
5682563	29167676	SP	2	provided the technical guidance and editing support	provided the technical guidance and editing support	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Review & Editing	YES
5682563	29167676	TZ	2	gathered the literature and contributed in arranging the data for different attributes	gathered the literature and contributed in arranging the data for different attributes	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5682563	29167676	ZY	2	had major and equal contribution in overall preparation	had major and equal contribution in overall preparation	-	-	NO
5682563	29167676	ZZ	2	had major and equal contribution in overall preparation	had major and equal contribution in overall preparation	-	-	NO
5236047	28091978	AS	2	carried out the objective and subjective assessments of the image quality	carried out the objective and subjective assessments of the image quality	Performed the experiments|Analyzed the data	Investigation|Validation|Visualization	YES
5236047	28091978	All authors	2	were involved in the overall design of the study and critically reviewed and approved the manuscript	were involved in the overall design of the study and critically reviewed and approved the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5236047	28091978	DP	2	was responsible for obtaining the regulatory approval for the study	was responsible for obtaining the regulatory approval for the study	-	Project administration	YES
5236047	28091978	FW	2	was involved in the patient recruitment, the data analysis, and the writing of the manuscript	was involved in the patient recruitment, the data analysis, and the writing of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5236047	28091978	HM	2	contributed towards the data analysis	contributed towards the data analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5236047	28091978	TW	2	carried out the objective and subjective assessments of the image quality	carried out the objective and subjective assessments of the image quality	Performed the experiments|Analyzed the data	Investigation|Validation|Visualization	YES
4575999	26436092	Chen Cui	2	are co-first authors	are co-first authors	-	-	NO
4575999	26436092	Yongjun Jiang	2	are co-first authors	are co-first authors	-	-	NO
2714833	19594929	AAW	2	was the primary author of the manuscript and played an important role in data collection and assessment	was the primary author of the manuscript and played an important role in data collection and assessment	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
2714833	19594929	EDR	2	played an important role in data collection and manuscript preparation	played an important role in data collection and manuscript preparation	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
2714833	19594929	JRS	2	played an important role in study design and manuscript preparation	played an important role in study design and manuscript preparation	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
2714833	19594929	JTC	2	was the senior author and played an important role in the grant procurement, study design, data analysis and interpretation, and manuscript preparation	was the senior author and played an important role in the grant procurement, study design, data analysis and interpretation, and manuscript preparation	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
2714833	19594929	KMH	2	played an important role in data collection and manuscript preparation	played an important role in data collection and manuscript preparation	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
2714833	19594929	PBC	2	played an important role in data collection and manuscript preparation	played an important role in data collection and manuscript preparation	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
2714833	19594929	TJH	2	played an important role in data collection and manuscript preparation	played an important role in data collection and manuscript preparation	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
2714833	19594929	TWB	2	played an important role in study design and manuscript preparation	played an important role in study design and manuscript preparation	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4412405	25919583	AD	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412405	25919583	AD	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412405	25919583	AM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412405	25919583	DS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412405	25919583	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412405	25919583	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412405	25919583	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412405	25919583	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412405	25919583	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412405	25919583	KO	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412405	25919583	NH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412405	25919583	NH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412405	25919583	NH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5110145	27867479	AK	2	performed research	performed research	Performed the experiments	Investigation	YES
5110145	27867479	AN	2	performed research|drafted manuscript	performed research	Performed the experiments	Investigation	YES
5110145	27867479	AN	2	performed research|drafted manuscript	drafted manuscript	Wrote the paper	Writing - Original Draft	YES
5110145	27867479	HY	2	performed research	performed research	Performed the experiments	Investigation	YES
5110145	27867479	JK	2	analyzed data and interpreted results of experiments	analyzed data and interpreted results of experiments	Analyzed the data	Formal analysis	YES
5110145	27867479	KK	2	performed research	performed research	Performed the experiments	Investigation	YES
5110145	27867479	KT	2	analyzed data and interpreted results of experiments	analyzed data and interpreted results of experiments	Analyzed the data	Formal analysis	YES
5110145	27867479	MI	2	performed research	performed research	Performed the experiments	Investigation	YES
5110145	27867479	NF	2	performed research	performed research	Performed the experiments	Investigation	YES
5110145	27867479	SL	2	analyzed data and interpreted results of experiments	analyzed data and interpreted results of experiments	Analyzed the data	Formal analysis	YES
5110145	27867479	TN	2	performed research	performed research	Performed the experiments	Investigation	YES
5110145	27867479	TYamada	2	performed research	performed research	Performed the experiments	Investigation	YES
5110145	27867479	TYumoto	2	analyzed data and interpreted results of experiments	analyzed data and interpreted results of experiments	Analyzed the data	Formal analysis	YES
1852332	17476327	AB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1852332	17476327	AB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1852332	17476327	AB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1852332	17476327	AB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1852332	17476327	AJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1852332	17476327	AJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1852332	17476327	AJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1852332	17476327	JZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1852332	17476327	JZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1852332	17476327	JZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
554769	15740627	Bryan Frank	2	contributed significantly to the development, implementation, and optimization of the protocol	contributed significantly to the development, implementation, and optimization of the protocol	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
554769	15740627	John Quackenbush	2	further developed the approach	further developed the approach	-	-	NO
554769	15740627	Nicholas Marko	2	further developed the approach	further developed the approach	-	-	NO
5237435	28091980	ALC	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5237435	28091980	All authors	PLoS52	edited and reviewed the manuscript	edited and reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5237435	28091980	CBH	PLoS52	analyzed the data|prepared the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5237435	28091980	CBH	PLoS52	analyzed the data|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5237435	28091980	DJR	PLoS52	carried out the protocol development and patient recruitment	carried out the protocol development and patient recruitment	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5237435	28091980	DLWR	PLoS52	carried out the protocol development and patient recruitment	carried out the protocol development and patient recruitment	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5237435	28091980	JCB	PLoS52	analyzed the data|carried out the protocol development and patient recruitment	analyzed the data	Analyzed the data	Formal analysis	YES
5237435	28091980	JCB	PLoS52	analyzed the data|carried out the protocol development and patient recruitment	carried out the protocol development and patient recruitment	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5237435	28091980	KNH	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5237435	28091980	MKO	PLoS52	analyzed the data|prepared the manuscript|carried out the protocol development and patient recruitment	analyzed the data	Analyzed the data	Formal analysis	YES
5237435	28091980	MKO	PLoS52	analyzed the data|prepared the manuscript|carried out the protocol development and patient recruitment	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5237435	28091980	MKO	PLoS52	analyzed the data|prepared the manuscript|carried out the protocol development and patient recruitment	carried out the protocol development and patient recruitment	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5237435	28091980	MMBM	PLoS52	analyzed the data|prepared the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5237435	28091980	MMBM	PLoS52	analyzed the data|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5683035	29167677	AZ	2	carried out the analysis|wrote the manuscript	carried out the analysis	Performed the experiments	Investigation	YES
5683035	29167677	AZ	2	carried out the analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5683035	29167677	BP	2	designed, led, and coordinated the overall study	designed, led, and coordinated the overall study	Conceived and designed the experiments	Methodology|Project administration	YES
5683035	29167677	FS	2	designed, led, and coordinated the overall study	designed, led, and coordinated the overall study	Conceived and designed the experiments	Methodology|Project administration	YES
5683035	29167677	HW	2	carried out the analysis|wrote the manuscript	carried out the analysis	Performed the experiments	Investigation	YES
5683035	29167677	HW	2	carried out the analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5683035	29167677	HY	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5683035	29167677	JB	2	carried out the analysis	carried out the analysis	Performed the experiments	Investigation	YES
5683035	29167677	JC	2	carried out the analysis	carried out the analysis	Performed the experiments	Investigation	YES
5683035	29167677	KS	2	performed and coordinated the genotyping work	performed and coordinated the genotyping work	Performed the experiments	Investigation|Project administration	YES
5683035	29167677	MO	2	designed, led, and coordinated the overall study	designed, led, and coordinated the overall study	Conceived and designed the experiments	Methodology|Project administration	YES
5683035	29167677	SC	2	carried out the analysis	carried out the analysis	Performed the experiments	Investigation	YES
5683035	29167677	XZ	2	designed, led, and coordinated the overall study|wrote the manuscript	designed, led, and coordinated the overall study	Conceived and designed the experiments	Methodology|Project administration	YES
5683035	29167677	XZ	2	designed, led, and coordinated the overall study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5683035	29167677	YB	2	designed, led, and coordinated the overall study|performed and coordinated the field experiments	designed, led, and coordinated the overall study	Conceived and designed the experiments	Methodology|Project administration	YES
5683035	29167677	YB	2	designed, led, and coordinated the overall study|performed and coordinated the field experiments	performed and coordinated the field experiments	Performed the experiments	Investigation|Project administration	YES
5683035	29167677	YL	2	carried out the analysis	carried out the analysis	Performed the experiments	Investigation	YES
5683035	29167677	YR	2	carried out the analysis	carried out the analysis	Performed the experiments	Investigation	YES
5683035	29167677	ZC	2	carried out the analysis	carried out the analysis	Performed the experiments	Investigation	YES
4581578	26448760	Edward V. Maytin	2	reviewed the abstract and introduction	reviewed the abstract and introduction	-	-	NO
4581578	26448760	Ilia Atanelishvili	2	helped to draw the figures	helped to draw the figures	-	Visualization	YES
4581578	26448760	Judith A. Mack	2	reviewed the abstract and introduction	reviewed the abstract and introduction	-	-	NO
4581578	26448760	Ricardo Moreno Rodriguez	2	helped to draw the figures	helped to draw the figures	-	Visualization	YES
4581578	26448760	Roger R. Markwald	2	edited the final paper	edited the final paper	Wrote the paper	Writing - Review & Editing	YES
4581578	26448760	Shibnath Ghatak	2	wrote the review	wrote the review	Wrote the paper	Writing - Original Draft	YES
4581578	26448760	Suniti Misra	2	wrote the review	wrote the review	Wrote the paper	Writing - Original Draft	YES
4581578	26448760	Vincent C. Hascall	2	reviewed the draft and final paper	reviewed the draft and final paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
2731073	19656392	BL	2	participated in the data acquisition	participated in the data acquisition	Performed the experiments	Investigation	YES
2731073	19656392	BS	2	assisted in coordination of the study, data acquisition, in performing the statistical analysis, and drafting the manuscript	assisted in coordination of the study, data acquisition, in performing the statistical analysis, and drafting the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Project administration|Writing - Original Draft	YES
2731073	19656392	DSW	2	conceived the study, developed the study design, secured the funding for the project, assisted and provided oversight for all data acquisition and statistical analysis, assisted and provided oversight in drafting the manuscript, and served as the faculty mentor for the project	conceived the study, developed the study design, secured the funding for the project, assisted and provided oversight for all data acquisition and statistical analysis, assisted and provided oversight in drafting the manuscript, and served as the faculty mentor for the project	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Funding acquisition|Investigation|Methodology|Resources|Supervision|Writing - Original Draft	YES
2731073	19656392	GH	2	participated in the data acquisition	participated in the data acquisition	Performed the experiments	Investigation	YES
2731073	19656392	LR	2	participated in the data acquisition	participated in the data acquisition	Performed the experiments	Investigation	YES
2731073	19656392	MC	2	participated in the data acquisition	participated in the data acquisition	Performed the experiments	Investigation	YES
2731073	19656392	TB	2	participated in the data acquisition	participated in the data acquisition	Performed the experiments	Investigation	YES
5223308	28217289	All authors	2	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5223308	28217289	LH	2	performed all the experiments, analyzed the data and prepared the figures	performed all the experiments, analyzed the data and prepared the figures	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
5223308	28217289	YD	2	conceived and designed the project|performed all the experiments, analyzed the data and prepared the figures|wrote the manuscript	conceived and designed the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5223308	28217289	YD	2	conceived and designed the project|performed all the experiments, analyzed the data and prepared the figures|wrote the manuscript	performed all the experiments, analyzed the data and prepared the figures	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
5223308	28217289	YD	2	conceived and designed the project|performed all the experiments, analyzed the data and prepared the figures|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5223308	28217289	YZ	2	conceived and designed the project	conceived and designed the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5223308	28217289	ZX	2	conceived and designed the project|conceived and designed the project|performed all the experiments, analyzed the data and prepared the figures|wrote the manuscript	conceived and designed the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5223308	28217289	ZX	2	conceived and designed the project|conceived and designed the project|performed all the experiments, analyzed the data and prepared the figures|wrote the manuscript	conceived and designed the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5223308	28217289	ZX	2	conceived and designed the project|conceived and designed the project|performed all the experiments, analyzed the data and prepared the figures|wrote the manuscript	performed all the experiments, analyzed the data and prepared the figures	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
5223308	28217289	ZX	2	conceived and designed the project|conceived and designed the project|performed all the experiments, analyzed the data and prepared the figures|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4052689	24949275	AB	2	was in charge of plasmid vector construction and confocal microscopy analysis, set up the transformation protocol and prepared the first draft of the manuscript	was in charge of plasmid vector construction and confocal microscopy analysis, set up the transformation protocol and prepared the first draft of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
4052689	24949275	BM	2	contributed to plasmid vector construction, confocal microscopy analysis, final editing of the manuscript and figure assembly	contributed to plasmid vector construction, confocal microscopy analysis, final editing of the manuscript and figure assembly	Performed the experiments|Wrote the paper	Investigation|Visualization|Writing - Review & Editing	YES
4052689	24949275	EM	2	performed tail-pcr experiments	performed tail-pcr experiments	Performed the experiments	Investigation	YES
4052689	24949275	PB	2	coordinated the project, designed part of the experiments and contributed to manuscript drafting	coordinated the project, designed part of the experiments and contributed to manuscript drafting	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft	YES
4052689	24949275	PF	2	contributed to data analysis	contributed to data analysis	Analyzed the data	Formal analysis	YES
4052689	24949275	SO	2	proposed the project, designed part of the experiments and wrote the last draft of the manuscript	proposed the project, designed part of the experiments and wrote the last draft of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
4412407	25919356	MSP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412407	25919356	MSP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412407	25919356	MSP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412407	25919356	MSP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412407	25919356	MSP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4664808	26664363	Each author	2	has participated sufficiently in the work and reviewed his/her role in the paper	has participated sufficiently in the work and reviewed his/her role in the paper	Wrote the paper	Writing - Review & Editing	YES
554773	15733318	Both authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
554773	15733318	C.M.	2	carried out all the analyses and interpreted the results|jointly wrote the manuscript	carried out all the analyses and interpreted the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
554773	15733318	C.M.	2	carried out all the analyses and interpreted the results|jointly wrote the manuscript	jointly wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
554773	15733318	E.G.	2	was involved in the design and supervision of the project|jointly wrote the manuscript	was involved in the design and supervision of the project	Conceived and designed the experiments	Methodology|Supervision	YES
554773	15733318	E.G.	2	was involved in the design and supervision of the project|jointly wrote the manuscript	jointly wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
2731074	19660118	ER	2	participated in the data acquisition and drafting the manuscript	participated in the data acquisition and drafting the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
2731074	19660118	KS	2	participated in the data acquisition and drafting the manuscript	participated in the data acquisition and drafting the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
2731074	19660118	MS	2	assisted in coordination of the study, data acquisition, in performing the statistical analysis, and drafting the manuscript	assisted in coordination of the study, data acquisition, in performing the statistical analysis, and drafting the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Project administration|Writing - Original Draft	YES
1852333	17476329	HS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1852333	17476329	HS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1852333	17476329	HT	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1852333	17476329	HT	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1852333	17476329	MF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1852333	17476329	MF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1852333	17476329	MF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4412408	25919010	BNA	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412408	25919010	BNA	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412408	25919010	BNA	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412408	25919010	JFO	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4412408	25919010	JFO	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4412408	25919010	JFO	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412408	25919010	QD	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412408	25919010	QD	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412408	25919010	QD	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412408	25919010	QD	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412408	25919010	SMD	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4412408	25919010	SMD	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412408	25919010	TL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4412408	25919010	TL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412408	25919010	UF	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4412408	25919010	UF	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5684119	29170672	SG	2	collected literatures and wrote the manuscript	collected literatures and wrote the manuscript	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5237436	28091979	AKOA	2	participated in data collection	participated in data collection	Performed the experiments	Investigation	YES
5237436	28091979	All authors	2	participated in the study design|participated in the data interpretation|critically revised the manuscript, and all authors approved the final version of the manuscript	participated in the study design	Conceived and designed the experiments	Methodology	YES
5237436	28091979	All authors	2	participated in the study design|participated in the data interpretation|critically revised the manuscript, and all authors approved the final version of the manuscript	participated in the data interpretation	Analyzed the data	Formal analysis	YES
5237436	28091979	All authors	2	participated in the study design|participated in the data interpretation|critically revised the manuscript, and all authors approved the final version of the manuscript	critically revised the manuscript, and all authors approved the final version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5237436	28091979	LJ	2	wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
5237436	28091979	OLN	2	participated in data collection	participated in data collection	Performed the experiments	Investigation	YES
5237436	28091979	PA	2	participated in data collection	participated in data collection	Performed the experiments	Investigation	YES
5223309	28217290	AO	2	revised the manuscipt	revised the manuscipt	Wrote the paper	Writing - Review & Editing	YES
5223309	28217290	JZ	2	is the corresponding author, participated in conceiving and revising of the manuscript	is the corresponding author, participated in conceiving and revising of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5223309	28217290	LH	2	conceived and drafted the manuscript, as well as, gathering the references	conceived and drafted the manuscript, as well as, gathering the references	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5223309	28217290	MH	2	performed the animal surgery and tissue histopathology	performed the animal surgery and tissue histopathology	Performed the experiments	Investigation	YES
5549306	28789618	CAH	2	formulated the research goal|contributed materials and analysis tools|wrote the manuscript	formulated the research goal	Conceived and designed the experiments	Conceptualization	YES
5549306	28789618	CAH	2	formulated the research goal|contributed materials and analysis tools|wrote the manuscript	contributed materials and analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5549306	28789618	CAH	2	formulated the research goal|contributed materials and analysis tools|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5549306	28789618	HLC	2	performed the cnv validation experiment	performed the cnv validation experiment	Performed the experiments	Investigation|Validation	YES
5549306	28789618	KDW	2	contributed materials and analysis tools	contributed materials and analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5549306	28789618	MWL	2	contributed materials and analysis tools	contributed materials and analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5549306	28789618	RHC	2	formulated the research goal|designed the methods and performed the analyses|wrote the manuscript	formulated the research goal	Conceived and designed the experiments	Conceptualization	YES
5549306	28789618	RHC	2	formulated the research goal|designed the methods and performed the analyses|wrote the manuscript	designed the methods and performed the analyses	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5549306	28789618	RHC	2	formulated the research goal|designed the methods and performed the analyses|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5549306	28789618	TQ	2	contributed materials and analysis tools	contributed materials and analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5549306	28789618	WJL	2	contributed materials and analysis tools	contributed materials and analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5549306	28789618	YDIC	2	contributed materials and analysis tools	contributed materials and analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5549306	28789618	YFC	2	formulated the research goal|designed the methods and performed the analyses|wrote the manuscript	formulated the research goal	Conceived and designed the experiments	Conceptualization	YES
5549306	28789618	YFC	2	formulated the research goal|designed the methods and performed the analyses|wrote the manuscript	designed the methods and performed the analyses	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5549306	28789618	YFC	2	formulated the research goal|designed the methods and performed the analyses|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5549306	28789618	YJH	2	contributed materials and analysis tools	contributed materials and analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4576004	26436096	Eun-Joo Choi	2	equally contributed to this study	equally contributed to this study	-	-	NO
4576004	26436096	Kyung-Suk Moon	2	equally contributed to this study	equally contributed to this study	-	-	NO
2780977	19909536	AS	2	contributed in writing and editing the manuscript along with concept and design, data acquisition, and data analysis and interpretation	contributed in writing and editing the manuscript along with concept and design, data acquisition, and data analysis and interpretation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
2780977	19909536	DF	2	contributed in writing and editing the manuscript along with concept and design, data acquisition, and data analysis and interpretation	contributed in writing and editing the manuscript along with concept and design, data acquisition, and data analysis and interpretation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
2780977	19909536	JC	2	contributed in writing and editing the manuscript, as well as concept and design	contributed in writing and editing the manuscript, as well as concept and design	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
2780977	19909536	JG	2	contributed in writing and editing the manuscript along with concept and design, data acquisition, and data analysis and interpretation	contributed in writing and editing the manuscript along with concept and design, data acquisition, and data analysis and interpretation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
2780977	19909536	JM	2	contributed in writing and editing the manuscript, as well as concept and design	contributed in writing and editing the manuscript, as well as concept and design	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
2780977	19909536	JS	2	contributed in writing and editing the manuscript, as well as concept and design	contributed in writing and editing the manuscript, as well as concept and design	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
2780977	19909536	KK	2	contributed in writing and editing the manuscript along with concept and design, data acquisition, and data analysis and interpretation	contributed in writing and editing the manuscript along with concept and design, data acquisition, and data analysis and interpretation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
2780977	19909536	TB	2	contributed in writing and editing the manuscript, as well as concept and design	contributed in writing and editing the manuscript, as well as concept and design	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
4680051	26713093	All authors	2	contributed equally to this work	contributed equally to this work	-	-	NO
1852582	17476325	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1852582	17476325	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1852582	17476325	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1852582	17476325	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1852582	17476325	IS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1852582	17476325	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1852582	17476325	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1852582	17476325	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1852582	17476325	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412409	25919014	JY	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412409	25919014	LL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412409	25919014	MC	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4412409	25919014	NF	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412409	25919014	XL	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412409	25919014	XL	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412409	25919014	Ying Wang	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4412409	25919014	Yun Wang	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412409	25919014	Yun Wang	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412409	25919014	ZW	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4412409	25919014	ZW	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5241264	28097640	All authors	PLoS52	commented on this manuscript and approved the final manuscript	commented on this manuscript and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5241264	28097640	BL	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5241264	28097640	BW	PLoS52	contributed reagents/materials/analysis tools	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5241264	28097640	EFA	PLoS52	conceived and designed the experiments|analyzed the data|contributed reagents/materials/analysis tools|drafted the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5241264	28097640	EFA	PLoS52	conceived and designed the experiments|analyzed the data|contributed reagents/materials/analysis tools|drafted the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5241264	28097640	EFA	PLoS52	conceived and designed the experiments|analyzed the data|contributed reagents/materials/analysis tools|drafted the manuscript	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5241264	28097640	EFA	PLoS52	conceived and designed the experiments|analyzed the data|contributed reagents/materials/analysis tools|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5241264	28097640	HJ	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5241264	28097640	HJ	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5241264	28097640	JD	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|drafted the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5241264	28097640	JD	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|drafted the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5241264	28097640	JD	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|drafted the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5241264	28097640	JD	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5241264	28097640	JS	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|drafted the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5241264	28097640	JS	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|drafted the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5241264	28097640	JS	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|drafted the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5241264	28097640	JS	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5241264	28097640	KH	PLoS52	contributed reagents/materials/analysis tools	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5241264	28097640	ML	PLoS52	analyzed the data|contributed reagents/materials/analysis tools	analyzed the data	Analyzed the data	Formal analysis	YES
5241264	28097640	ML	PLoS52	analyzed the data|contributed reagents/materials/analysis tools	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5241264	28097640	MM	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|drafted the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5241264	28097640	MM	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|drafted the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5241264	28097640	MM	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|drafted the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5241264	28097640	MM	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5241264	28097640	ON	PLoS52	analyzed the data|contributed reagents/materials/analysis tools|drafted the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5241264	28097640	ON	PLoS52	analyzed the data|contributed reagents/materials/analysis tools|drafted the manuscript	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5241264	28097640	ON	PLoS52	analyzed the data|contributed reagents/materials/analysis tools|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5241264	28097640	TZP	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5241264	28097640	YA	PLoS52	analyzed the data|contributed reagents/materials/analysis tools|drafted the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5241264	28097640	YA	PLoS52	analyzed the data|contributed reagents/materials/analysis tools|drafted the manuscript	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5241264	28097640	YA	PLoS52	analyzed the data|contributed reagents/materials/analysis tools|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5223310	28217291	HW	PLoS52	contributed equally to this work|designed this paper|wrote the paper	contributed equally to this work	-	-	NO
5223310	28217291	HW	PLoS52	contributed equally to this work|designed this paper|wrote the paper	designed this paper	Conceived and designed the experiments	-	YES
5223310	28217291	HW	PLoS52	contributed equally to this work|designed this paper|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5223310	28217291	LZ	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5223310	28217291	MC	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5223310	28217291	NX	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5223310	28217291	PL	PLoS52	contributed equally to this work|wrote the paper|reviewed this paper	contributed equally to this work	-	-	NO
5223310	28217291	PL	PLoS52	contributed equally to this work|wrote the paper|reviewed this paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5223310	28217291	PL	PLoS52	contributed equally to this work|wrote the paper|reviewed this paper	reviewed this paper	Wrote the paper	Writing - Review & Editing	YES
5223310	28217291	WY	PLoS52	reviewed this paper	reviewed this paper	Wrote the paper	Writing - Review & Editing	YES
5223310	28217291	YG	PLoS52	designed this paper|reviewed this paper	designed this paper	Conceived and designed the experiments	-	YES
5223310	28217291	YG	PLoS52	designed this paper|reviewed this paper	reviewed this paper	Wrote the paper	Writing - Review & Editing	YES
5684126	29170673	AC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5684126	29170673	BeL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5684126	29170673	BoL	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5684126	29170673	BoL	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5684126	29170673	HJ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5684126	29170673	HJ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5684126	29170673	LW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5684126	29170673	LW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
5684126	29170673	LW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5684126	29170673	LW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5684126	29170673	LY	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5684126	29170673	LY	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5684126	29170673	WG	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5684126	29170673	XD	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5684126	29170673	XR	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5684126	29170673	YC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5684126	29170673	YL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5684126	29170673	YL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2818616	20051111	AAM	2	conceived the study, developed the study design, participated in data acquisition and drafting the manuscript	conceived the study, developed the study design, participated in data acquisition and drafting the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Writing - Original Draft	YES
2818616	20051111	JJH	2	assisted with the design of the study, and the manuscript preparation	assisted with the design of the study, and the manuscript preparation	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
2818616	20051111	RP	2	collected blood samples and analyzed them	collected blood samples and analyzed them	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
2818616	20051111	TAMK	2	assisted with the design of the study and drafting the manuscript	assisted with the design of the study and drafting the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
2818616	20051111	TO	2	developed the study design, participated in the data acquisition and assisted in drafting the manuscript	developed the study design, participated in the data acquisition and assisted in drafting the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
2818616	20051111	TS	2	assisted with the design of the study and drafting the manuscript	assisted with the design of the study and drafting the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5223311	28217292	WCL	2	reviewed the studies, wrote up the manuscript	reviewed the studies, wrote up the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5223311	28217292	XCJ	2	participated in the overall design of the review and obtained partial funding	participated in the overall design of the review and obtained partial funding	Conceived and designed the experiments	Funding acquisition	YES
5549309	28789640	AP	2	contributed to bioinformatics analyses and supervised the pipeline of analysis	contributed to bioinformatics analyses and supervised the pipeline of analysis	Analyzed the data	Formal analysis|Supervision	YES
5549309	28789640	All the authors	2	provided a critical contribution for the improvement of the first draft of the manuscript and approved its final version	provided a critical contribution for the improvement of the first draft of the manuscript and approved its final version	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5549309	28789640	FS	2	extracted rna from samples, evaluated its quality, prepared sequencing libraries and performed validation experiments by rt pcr	extracted rna from samples, evaluated its quality, prepared sequencing libraries and performed validation experiments by rt pcr	Performed the experiments	Investigation|Validation	YES
5549309	28789640	HF	2	provided inputs for the biological interpretation of results and performed the analysis of lectin gene families	provided inputs for the biological interpretation of results and performed the analysis of lectin gene families	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5549309	28789640	IH	2	provided inputs for the biological interpretation of results and performed the analysis of lectin gene families	provided inputs for the biological interpretation of results and performed the analysis of lectin gene families	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5549309	28789640	KY	2	collected the biological material, dissected the animals and prepared tissues for rna extraction	collected the biological material, dissected the animals and prepared tissues for rna extraction	Performed the experiments	Investigation	YES
5549309	28789640	MG	2	performed the assembly, annotation and bioinformatics analyses, designed validation experiments and wrote the paper|conceived the project and experimental plan	performed the assembly, annotation and bioinformatics analyses, designed validation experiments and wrote the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Formal analysis|Investigation|Methodology|Validation|Writing - Original Draft	YES
5549309	28789640	MG	2	performed the assembly, annotation and bioinformatics analyses, designed validation experiments and wrote the paper|conceived the project and experimental plan	conceived the project and experimental plan	Conceived and designed the experiments	Conceptualization	YES
5549309	28789640	SS	2	collected the biological material, dissected the animals and prepared tissues for rna extraction	collected the biological material, dissected the animals and prepared tissues for rna extraction	Performed the experiments	Investigation	YES
5549309	28789640	TK	2	collected the biological material, dissected the animals and prepared tissues for rna extraction	collected the biological material, dissected the animals and prepared tissues for rna extraction	Performed the experiments	Investigation	YES
5549309	28789640	YF	2	conceived the project and experimental plan|collected the biological material, dissected the animals and prepared tissues for rna extraction|provided inputs for the biological interpretation of results and performed the analysis of lectin gene families	conceived the project and experimental plan	Conceived and designed the experiments	Conceptualization	YES
5549309	28789640	YF	2	conceived the project and experimental plan|collected the biological material, dissected the animals and prepared tissues for rna extraction|provided inputs for the biological interpretation of results and performed the analysis of lectin gene families	collected the biological material, dissected the animals and prepared tissues for rna extraction	Performed the experiments	Investigation	YES
5549309	28789640	YF	2	conceived the project and experimental plan|collected the biological material, dissected the animals and prepared tissues for rna extraction|provided inputs for the biological interpretation of results and performed the analysis of lectin gene families	provided inputs for the biological interpretation of results and performed the analysis of lectin gene families	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5549309	28789640	YO	2	provided inputs for the biological interpretation of results and performed the analysis of lectin gene families	provided inputs for the biological interpretation of results and performed the analysis of lectin gene families	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
1852583	17476322	AH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1852583	17476322	AH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1852583	17476322	AH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1852583	17476322	AR	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1852583	17476322	AR	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1852583	17476322	BQ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1852583	17476322	BQ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1852583	17476322	BQ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1852583	17476322	BQ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1852583	17476322	MK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1852583	17476322	MK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1852583	17476322	MK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1852583	17476322	RP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1852583	17476322	RP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1852583	17476322	RP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1852583	17476322	RP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5241570	28101850	AMC	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5241570	28101850	AS	PLoS52	are involved in the study design|performed the experiments|performed the data analysis	are involved in the study design	Conceived and designed the experiments	Methodology	YES
5241570	28101850	AS	PLoS52	are involved in the study design|performed the experiments|performed the data analysis	performed the experiments	Performed the experiments	Investigation	YES
5241570	28101850	AS	PLoS52	are involved in the study design|performed the experiments|performed the data analysis	performed the data analysis	Analyzed the data	Formal analysis	YES
5241570	28101850	CV	PLoS52	are involved in the study design|performed the experiments|performed the data analysis|drafted the manuscript	are involved in the study design	Conceived and designed the experiments	Methodology	YES
5241570	28101850	CV	PLoS52	are involved in the study design|performed the experiments|performed the data analysis|drafted the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5241570	28101850	CV	PLoS52	are involved in the study design|performed the experiments|performed the data analysis|drafted the manuscript	performed the data analysis	Analyzed the data	Formal analysis	YES
5241570	28101850	CV	PLoS52	are involved in the study design|performed the experiments|performed the data analysis|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5241570	28101850	FH	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5241570	28101850	JM	PLoS52	are involved in the study design|performed the experiments|performed the data analysis	are involved in the study design	Conceived and designed the experiments	Methodology	YES
5241570	28101850	JM	PLoS52	are involved in the study design|performed the experiments|performed the data analysis	performed the experiments	Performed the experiments	Investigation	YES
5241570	28101850	JM	PLoS52	are involved in the study design|performed the experiments|performed the data analysis	performed the data analysis	Analyzed the data	Formal analysis	YES
5241570	28101850	JP	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5241570	28101850	JRC	PLoS52	are involved in the study design	are involved in the study design	Conceived and designed the experiments	Methodology	YES
5241570	28101850	RAM	PLoS52	are involved in the study design|performed the experiments	are involved in the study design	Conceived and designed the experiments	Methodology	YES
5241570	28101850	RAM	PLoS52	are involved in the study design|performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5241570	28101850	SE	PLoS52	are involved in the study design|performed the experiments|performed the data analysis|drafted the manuscript	are involved in the study design	Conceived and designed the experiments	Methodology	YES
5241570	28101850	SE	PLoS52	are involved in the study design|performed the experiments|performed the data analysis|drafted the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5241570	28101850	SE	PLoS52	are involved in the study design|performed the experiments|performed the data analysis|drafted the manuscript	performed the data analysis	Analyzed the data	Formal analysis	YES
5241570	28101850	SE	PLoS52	are involved in the study design|performed the experiments|performed the data analysis|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5684173	29170675	DU	2	conducted the voc analysis|drafted the manuscript|contributed to the discussion and interpretation of results and read and approved the final manuscript	conducted the voc analysis	Performed the experiments	Investigation	YES
5684173	29170675	DU	2	conducted the voc analysis|drafted the manuscript|contributed to the discussion and interpretation of results and read and approved the final manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5684173	29170675	DU	2	conducted the voc analysis|drafted the manuscript|contributed to the discussion and interpretation of results and read and approved the final manuscript	contributed to the discussion and interpretation of results and read and approved the final manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5684173	29170675	FD	2	conceived and designed the experimental layout|performed the manual curation and evaluation of transcript predictions and compiled the carrot tps gene family|drafted the manuscript|contributed to the discussion and interpretation of results and read and approved the final manuscript	conceived and designed the experimental layout	Conceived and designed the experiments	Conceptualization|Methodology	YES
5684173	29170675	FD	2	conceived and designed the experimental layout|performed the manual curation and evaluation of transcript predictions and compiled the carrot tps gene family|drafted the manuscript|contributed to the discussion and interpretation of results and read and approved the final manuscript	performed the manual curation and evaluation of transcript predictions and compiled the carrot tps gene family	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5684173	29170675	FD	2	conceived and designed the experimental layout|performed the manual curation and evaluation of transcript predictions and compiled the carrot tps gene family|drafted the manuscript|contributed to the discussion and interpretation of results and read and approved the final manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5684173	29170675	FD	2	conceived and designed the experimental layout|performed the manual curation and evaluation of transcript predictions and compiled the carrot tps gene family|drafted the manuscript|contributed to the discussion and interpretation of results and read and approved the final manuscript	contributed to the discussion and interpretation of results and read and approved the final manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5684173	29170675	HB	2	conceived and designed the experimental layout|contributed to the discussion and interpretation of results and read and approved the final manuscript	conceived and designed the experimental layout	Conceived and designed the experiments	Conceptualization|Methodology	YES
5684173	29170675	HB	2	conceived and designed the experimental layout|contributed to the discussion and interpretation of results and read and approved the final manuscript	contributed to the discussion and interpretation of results and read and approved the final manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5684173	29170675	HL	2	performed the bioinformatic analysis|drafted the manuscript|contributed to the discussion and interpretation of results and read and approved the final manuscript	performed the bioinformatic analysis	Performed the experiments	Formal analysis|Investigation	YES
5684173	29170675	HL	2	performed the bioinformatic analysis|drafted the manuscript|contributed to the discussion and interpretation of results and read and approved the final manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5684173	29170675	HL	2	performed the bioinformatic analysis|drafted the manuscript|contributed to the discussion and interpretation of results and read and approved the final manuscript	contributed to the discussion and interpretation of results and read and approved the final manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5684173	29170675	JK	2	conceived and designed the experimental layout|performed the bioinformatic analysis|drafted the manuscript|contributed to the discussion and interpretation of results and read and approved the final manuscript	conceived and designed the experimental layout	Conceived and designed the experiments	Conceptualization|Methodology	YES
5684173	29170675	JK	2	conceived and designed the experimental layout|performed the bioinformatic analysis|drafted the manuscript|contributed to the discussion and interpretation of results and read and approved the final manuscript	performed the bioinformatic analysis	Performed the experiments	Formal analysis|Investigation	YES
5684173	29170675	JK	2	conceived and designed the experimental layout|performed the bioinformatic analysis|drafted the manuscript|contributed to the discussion and interpretation of results and read and approved the final manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5684173	29170675	JK	2	conceived and designed the experimental layout|performed the bioinformatic analysis|drafted the manuscript|contributed to the discussion and interpretation of results and read and approved the final manuscript	contributed to the discussion and interpretation of results and read and approved the final manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5684173	29170675	TB	2	performed the bioinformatic analysis	performed the bioinformatic analysis	Performed the experiments	Formal analysis|Investigation	YES
5684173	29170675	TN	2	conceived and designed the experimental layout|contributed to the discussion and interpretation of results and read and approved the final manuscript	conceived and designed the experimental layout	Conceived and designed the experiments	Conceptualization|Methodology	YES
5684173	29170675	TN	2	conceived and designed the experimental layout|contributed to the discussion and interpretation of results and read and approved the final manuscript	contributed to the discussion and interpretation of results and read and approved the final manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4412412	25919003	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412412	25919003	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412412	25919003	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412412	25919003	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412412	25919003	BA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412412	25919003	BA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412412	25919003	BA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412412	25919003	CFR	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412412	25919003	CFR	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412412	25919003	DF	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412412	25919003	DF	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412412	25919003	JMP	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412412	25919003	JMP	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412412	25919003	KT	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412412	25919003	KT	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412412	25919003	KT	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2821364	20157419	All authors	2	reviewed and approved the final manuscript	reviewed and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
2821364	20157419	JB	2	all contributed to the study design	all contributed to the study design	Conceived and designed the experiments	Methodology	YES
2821364	20157419	JF	2	all contributed to the study design	all contributed to the study design	Conceived and designed the experiments	Methodology	YES
2821364	20157419	MW	2	all contributed to the study design|both interpreted the data	all contributed to the study design	Conceived and designed the experiments	Methodology	YES
2821364	20157419	MW	2	all contributed to the study design|both interpreted the data	both interpreted the data	Analyzed the data	Formal analysis	YES
2821364	20157419	NW	2	recruited participants and conducted all data collection	recruited participants and conducted all data collection	Performed the experiments	Investigation	YES
2821364	20157419	SB	2	all contributed to the study design|recruited participants and conducted all data collection|undertook analysis of all the data|both interpreted the data	all contributed to the study design	Conceived and designed the experiments	Methodology	YES
2821364	20157419	SB	2	all contributed to the study design|recruited participants and conducted all data collection|undertook analysis of all the data|both interpreted the data	recruited participants and conducted all data collection	Performed the experiments	Investigation	YES
2821364	20157419	SB	2	all contributed to the study design|recruited participants and conducted all data collection|undertook analysis of all the data|both interpreted the data	undertook analysis of all the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
2821364	20157419	SB	2	all contributed to the study design|recruited participants and conducted all data collection|undertook analysis of all the data|both interpreted the data	both interpreted the data	Analyzed the data	Formal analysis	YES
5223312	28217293	CHH	2	drafting the article	drafting the article	Wrote the paper	Writing - Original Draft	YES
5223312	28217293	HL	2	literature collecting and analysis	literature collecting and analysis	-	Formal analysis	YES
5223312	28217293	WWL	2	structuring, revising and confirming the article	structuring, revising and confirming the article	Wrote the paper	Writing - Review & Editing	YES
5223312	28217293	XJS	2	designing this article	designing this article	Conceived and designed the experiments	-	YES
1853232	17476334	MW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1853232	17476334	MW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1853232	17476334	MW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1853232	17476334	MW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412475	25919759	CB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412475	25919759	CB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4412475	25919759	CB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4412475	25919759	CB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412475	25919759	CBU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412475	25919759	CBU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412475	25919759	CBU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412475	25919759	CBU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412475	25919759	CBU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412475	25919759	CR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412475	25919759	CR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412475	25919759	CR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412475	25919759	CR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412475	25919759	CR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412475	25919759	DWL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412475	25919759	DWL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412475	25919759	DWL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412475	25919759	DWL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412475	25919759	DWL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412475	25919759	GM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412475	25919759	GM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4412475	25919759	GM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4412475	25919759	GM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412475	25919759	JEO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412475	25919759	JEO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412475	25919759	JEO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412475	25919759	JEO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412475	25919759	JEO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412475	25919759	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412475	25919759	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412475	25919759	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412475	25919759	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412475	25919759	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412475	25919759	MW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412475	25919759	MW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4412475	25919759	MW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4412475	25919759	MW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412475	25919759	RH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412475	25919759	RH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4412475	25919759	RH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4412475	25919759	RH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412475	25919759	SG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412475	25919759	SG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412475	25919759	SG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412475	25919759	SG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412475	25919759	SG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2822829	20205750	CMM	2	participated in concept, design, coordination and helped draft the manuscript	participated in concept, design, coordination and helped draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Project administration|Writing - Original Draft	YES
2822829	20205750	GH	2	participated in concept, design, coordination and helped draft the manuscript	participated in concept, design, coordination and helped draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Project administration|Writing - Original Draft	YES
2822829	20205750	KAC	2	supervised and sweat analysis	supervised and sweat analysis	-	Supervision	YES
2822829	20205750	MSG	2	supervised and sweat analysis	supervised and sweat analysis	-	Supervision	YES
2822829	20205750	SASC	2	conceived the study, supervised, statistical analysis, manuscript preparation	conceived the study, supervised, statistical analysis, manuscript preparation	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Supervision|Writing - Original Draft	YES
2822829	20205750	SHZ	2	participated in concept, design, coordination and helped draft the manuscript	participated in concept, design, coordination and helped draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Project administration|Writing - Original Draft	YES
2822829	20205750	SSC	2	was the primary investigator, study design, data collection/analysis and manuscript draft	was the primary investigator, study design, data collection/analysis and manuscript draft	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5223313	28217294	LH	2	conceived and wrote the manuscript as well as gathered the references	conceived and wrote the manuscript as well as gathered the references	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5247390	28102506	AT	2	participated in data collection, image analysis, and data interpretation	participated in data collection, image analysis, and data interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
5247390	28102506	CR	2	participated in the design of the study and revision of the manuscript	participated in the design of the study and revision of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5247390	28102506	DS	2	lead this study at the multicenter sites and participated in data collection	lead this study at the multicenter sites and participated in data collection	Performed the experiments	Investigation	YES
5247390	28102506	EG	2	helped design the trial and analyzed the tumor samples	helped design the trial and analyzed the tumor samples	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5247390	28102506	GE	2	lead this study at the multicenter sites and participated in data collection	lead this study at the multicenter sites and participated in data collection	Performed the experiments	Investigation	YES
5247390	28102506	JB	2	participated in the design of the study and revision of the manuscript	participated in the design of the study and revision of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5247390	28102506	JC	2	participated in data collection, study management, data analysis, and prepared the manuscript	participated in data collection, study management, data analysis, and prepared the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Formal analysis|Investigation|Writing - Original Draft	YES
5247390	28102506	JL	2	participated in data management, trial design, and data analysis	participated in data management, trial design, and data analysis	Conceived and designed the experiments|Analyzed the data	Data curation|Formal analysis|Project administration	YES
5247390	28102506	JO	2	participated in data collection, image analysis, and data interpretation	participated in data collection, image analysis, and data interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
5247390	28102506	LK	2	participated in the design of the study and revision of the manuscript	participated in the design of the study and revision of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5247390	28102506	MK	2	lead this study at the multicenter sites and participated in data collection	lead this study at the multicenter sites and participated in data collection	Performed the experiments	Investigation	YES
5247390	28102506	ML	2	participated in data management, trial design, and data analysis	participated in data management, trial design, and data analysis	Conceived and designed the experiments|Analyzed the data	Data curation|Formal analysis|Project administration	YES
5247390	28102506	NH	2	lead this study at the multicenter sites and participated in data collection	lead this study at the multicenter sites and participated in data collection	Performed the experiments	Investigation	YES
5247390	28102506	PG	2	helped manage the trial and participated in data collection and analysis	helped manage the trial and participated in data collection and analysis	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation|Project administration	YES
5247390	28102506	RJ	2	participated in the design of the study and revision of the manuscript	participated in the design of the study and revision of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5247390	28102506	RW	2	participated in trial design, image analysis, data interpretation, and manuscript revision	participated in trial design, image analysis, data interpretation, and manuscript revision	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Visualization|Writing - Review & Editing	YES
5684176	29170677	All authors	2	commented on the article	commented on the article	-	-	NO
5684176	29170677	BW	2	conceived this project and designed all experiments|analyzed the data and wrote the paper	conceived this project and designed all experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5684176	29170677	BW	2	conceived this project and designed all experiments|analyzed the data and wrote the paper	analyzed the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5684176	29170677	GL	2	performed some of the experiments	performed some of the experiments	Performed the experiments	Investigation	YES
5684176	29170677	HY	2	analyzed the data and wrote the paper	analyzed the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5684176	29170677	JL	2	conceived this project and designed all experiments|analyzed the data and wrote the paper	conceived this project and designed all experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5684176	29170677	JL	2	conceived this project and designed all experiments|analyzed the data and wrote the paper	analyzed the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5684176	29170677	LJ	2	performed some of the experiments	performed some of the experiments	Performed the experiments	Investigation	YES
5684176	29170677	LW	2	performed some of the experiments	performed some of the experiments	Performed the experiments	Investigation	YES
5684176	29170677	MC	2	performed some of the experiments	performed some of the experiments	Performed the experiments	Investigation	YES
5684176	29170677	QH	2	conceived this project and designed all experiments|performed some of the experiments|analyzed the data and wrote the paper	conceived this project and designed all experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5684176	29170677	QH	2	conceived this project and designed all experiments|performed some of the experiments|analyzed the data and wrote the paper	performed some of the experiments	Performed the experiments	Investigation	YES
5684176	29170677	QH	2	conceived this project and designed all experiments|performed some of the experiments|analyzed the data and wrote the paper	analyzed the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5684176	29170677	SL	2	performed some of the experiments	performed some of the experiments	Performed the experiments	Investigation	YES
5684176	29170677	XM	2	performed some of the experiments	performed some of the experiments	Performed the experiments	Investigation	YES
5684176	29170677	XS	2	performed some of the experiments	performed some of the experiments	Performed the experiments	Investigation	YES
5684176	29170677	YH	2	conceived this project and designed all experiments|performed some of the experiments|analyzed the data and wrote the paper	conceived this project and designed all experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5684176	29170677	YH	2	conceived this project and designed all experiments|performed some of the experiments|analyzed the data and wrote the paper	performed some of the experiments	Performed the experiments	Investigation	YES
5684176	29170677	YH	2	conceived this project and designed all experiments|performed some of the experiments|analyzed the data and wrote the paper	analyzed the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5684176	29170677	YJ	2	performed some of the experiments	performed some of the experiments	Performed the experiments	Investigation	YES
5549340	28789611	All authors	2	contributed to the writing of the article	contributed to the writing of the article	Wrote the paper	Writing - Original Draft	YES
5549340	28789611	CR	2	provided support with the bioinformatics and statistics analysis	provided support with the bioinformatics and statistics analysis	Analyzed the data	Formal analysis	YES
5549340	28789611	DR	2	supervised and coordinated the project	supervised and coordinated the project	-	Project administration|Supervision	YES
5549340	28789611	MR	2	carried out the experiment and analyzed the data	carried out the experiment and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5549340	28789611	PEC	2	carried out the experiment and analyzed the data	carried out the experiment and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4052774	24949271	KVV	2	helped to draft the manuscript	helped to draft the manuscript	Wrote the paper	Writing - Original Draft	YES
4052774	24949271	SKN	2	designed and carried out the experiments, analyse the data and write the manuscript	designed and carried out the experiments, analyse the data and write the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5223314	28217295	FZ	2	collected the references and drafted the manuscript	collected the references and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5223314	28217295	TY	2	collected the references and drafted the manuscript	collected the references and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5223314	28217295	YS	2	collected the references and drafted the manuscript	collected the references and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
2822830	20205751	AAM	2	conceived the study, developed the study design, participated in data acquisition and drafting the manuscript	conceived the study, developed the study design, participated in data acquisition and drafting the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Writing - Original Draft	YES
2822830	20205751	HHo	2	assisted with the design of the study and drafting the manuscript	assisted with the design of the study and drafting the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
2822830	20205751	HHu	2	developed the study design, participated in the data acquisition and assisted in drafting the manuscript|designed the diets and supervised the subjects during the weight reduction period	developed the study design, participated in the data acquisition and assisted in drafting the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
2822830	20205751	HHu	2	developed the study design, participated in the data acquisition and assisted in drafting the manuscript|designed the diets and supervised the subjects during the weight reduction period	designed the diets and supervised the subjects during the weight reduction period	Conceived and designed the experiments	Supervision	YES
2822830	20205751	JJH	2	assisted with the design of the study and the manuscript preparation	assisted with the design of the study and the manuscript preparation	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
2822830	20205751	OM	2	developed the study design, participated in the data acquisition and assisted in drafting the manuscript|designed the diets and supervised the subjects during the weight reduction period	developed the study design, participated in the data acquisition and assisted in drafting the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
2822830	20205751	OM	2	developed the study design, participated in the data acquisition and assisted in drafting the manuscript|designed the diets and supervised the subjects during the weight reduction period	designed the diets and supervised the subjects during the weight reduction period	Conceived and designed the experiments	Supervision	YES
2822830	20205751	RP	2	collected blood samples and analyzed them	collected blood samples and analyzed them	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
2822830	20205751	TAMK	2	assisted with the design of the study and drafting the manuscript	assisted with the design of the study and drafting the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4412479	25919375	JLH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412479	25919375	JLH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412479	25919375	JLH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412479	25919375	JLH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412479	25919375	JLH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412479	25919375	KI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412479	25919375	KI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412479	25919375	KI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412479	25919375	KI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412479	25919375	KI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412479	25919375	TM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412479	25919375	TM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412479	25919375	TM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412479	25919375	TQN	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412479	25919375	TQN	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412479	25919375	TQN	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1853233	17476324	CR	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1853233	17476324	CR	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1853233	17476324	ER	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1853233	17476324	ER	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1853233	17476324	FR	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1853233	17476324	FR	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1853233	17476324	MP	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1853233	17476324	MP	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1853233	17476324	MT	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1853233	17476324	MT	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1853233	17476324	MT	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1853233	17476324	TE	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1853233	17476324	TE	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1853233	17476324	TE	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2822831	20205771	AM	2	designed and carried out the metabonomics experiments	designed and carried out the metabonomics experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
2822831	20205771	All authors	2	contributed in the drafting of the manuscript and approved the final manuscript	contributed in the drafting of the manuscript and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
2822831	20205771	HCB	2	designed and carried out the metabonomics experiments	designed and carried out the metabonomics experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
2822831	20205771	IKS	2	carried out the cellular experiments for proteomics and metabonomics studies	carried out the cellular experiments for proteomics and metabonomics studies	Performed the experiments	Investigation	YES
2822831	20205771	JFY	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
2822831	20205771	NCN	2	designed and carried out the metabonomics experiments	designed and carried out the metabonomics experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5684186	29170678	H-YY	2	designed the study|performed the laboratory experiments|performed the data collection, statistical analysis and figure mapping|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5684186	29170678	H-YY	2	designed the study|performed the laboratory experiments|performed the data collection, statistical analysis and figure mapping|wrote the manuscript	performed the laboratory experiments	Performed the experiments	Investigation	YES
5684186	29170678	H-YY	2	designed the study|performed the laboratory experiments|performed the data collection, statistical analysis and figure mapping|wrote the manuscript	performed the data collection, statistical analysis and figure mapping	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
5684186	29170678	H-YY	2	designed the study|performed the laboratory experiments|performed the data collection, statistical analysis and figure mapping|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5684186	29170678	ST	2	designed the study|provided scientific expertise	designed the study	Conceived and designed the experiments	Methodology	YES
5684186	29170678	ST	2	designed the study|provided scientific expertise	provided scientific expertise	-	-	NO
5684186	29170678	TI	2	designed the study|provided scientific expertise	designed the study	Conceived and designed the experiments	Methodology	YES
5684186	29170678	TI	2	designed the study|provided scientific expertise	provided scientific expertise	-	-	NO
5684186	29170678	TM	2	performed the data collection, statistical analysis and figure mapping	performed the data collection, statistical analysis and figure mapping	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
5247395	28102507	AT	2	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5247395	28102507	CAU	2	performed and analyzed the in vitro and in vivo studies and contributed to the writing of the manuscript and preparation of the figures	performed and analyzed the in vitro and in vivo studies and contributed to the writing of the manuscript and preparation of the figures	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Visualization|Writing - Original Draft	YES
5247395	28102507	CM	2	designed the study, supervised the practical experiments, and finalized the manuscript and figures	designed the study, supervised the practical experiments, and finalized the manuscript and figures	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Visualization|Writing - Review & Editing	YES
5247395	28102507	MB	2	contributed to the experiments and writing of the manuscript	contributed to the experiments and writing of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5247395	28102507	RMS	2	assisted the in vitro and in vivo studies and reviewed the manuscript	assisted the in vitro and in vivo studies and reviewed the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5247395	28102507	RS	2	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5223315	28217296	JC	2	reviewed and approved the manuscript	reviewed and approved the manuscript	Wrote the paper	Writing - Review & Editing	YES
5223315	28217296	PYL	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5223315	28217296	RAS	2	revised the draft	revised the draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5223315	28217296	WFY	2	reviewed and approved the manuscript	reviewed and approved the manuscript	Wrote the paper	Writing - Review & Editing	YES
5223315	28217296	XW	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5549384	28789634	ABA	2	developed the r scripts	developed the r scripts	Contributed reagents/materials/analysis tools	Software	YES
5549384	28789634	NK	2	studied the conception	studied the conception	Conceived and designed the experiments	Conceptualization	YES
5549384	28789634	RA	2	performed the statistical study|is involved in data analysis and manuscript editing	performed the statistical study	Analyzed the data	Formal analysis	YES
5549384	28789634	RA	2	performed the statistical study|is involved in data analysis and manuscript editing	is involved in data analysis and manuscript editing	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5549384	28789634	RB	2	developed the r scripts	developed the r scripts	Contributed reagents/materials/analysis tools	Software	YES
5549384	28789634	SB	2	studied the conception|analyzed the data and drafted the manuscript|performed the statistical study|developed the r scripts	studied the conception	Conceived and designed the experiments	Conceptualization	YES
5549384	28789634	SB	2	studied the conception|analyzed the data and drafted the manuscript|performed the statistical study|developed the r scripts	analyzed the data and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5549384	28789634	SB	2	studied the conception|analyzed the data and drafted the manuscript|performed the statistical study|developed the r scripts	performed the statistical study	Analyzed the data	Formal analysis	YES
5549384	28789634	SB	2	studied the conception|analyzed the data and drafted the manuscript|performed the statistical study|developed the r scripts	developed the r scripts	Contributed reagents/materials/analysis tools	Software	YES
1853234	17476336	AY	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1853234	17476336	HM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1853234	17476336	HM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1853234	17476336	HM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1853234	17476336	HW	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1853234	17476336	HZ	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1853234	17476336	HZ	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1853234	17476336	II	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1853234	17476336	JE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1853234	17476336	JE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1853234	17476336	JE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1853234	17476336	JW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1853234	17476336	JW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1853234	17476336	JW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1853234	17476336	JW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1853234	17476336	JW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1853234	17476336	KF	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1853234	17476336	KF	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1853234	17476336	KY	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1853234	17476336	KY	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1853234	17476336	KY	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1853234	17476336	PI	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1853234	17476336	PI	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1853234	17476336	QY	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1853234	17476336	QY	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1853234	17476336	SA	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1853234	17476336	SA	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1853234	17476336	SA	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1853234	17476336	TH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1853234	17476336	TH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1853234	17476336	TH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1853234	17476336	YK	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1853234	17476336	YK	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1853234	17476336	YZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1853234	17476336	YZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1853234	17476336	YZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1853234	17476336	YZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4052778	24949273	CD	2	carried out the cytotoxicity and cell proliferation studies, and participated in the interpretation and discussion of the results	carried out the cytotoxicity and cell proliferation studies, and participated in the interpretation and discussion of the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4052778	24949273	CFL	2	participated in the design of the study, in the analysis and discussion of the cell cycle experiments, and helped to draft the manuscript	participated in the design of the study, in the analysis and discussion of the cell cycle experiments, and helped to draft the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
4052778	24949273	EJG	2	carried out the production of the biosurfactants and helped to draft the manuscript	carried out the production of the biosurfactants and helped to draft the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4052778	24949273	LRR	2	conceived of the study, participated in its design and coordination, performed the statistical analysis and drafted the manuscript	conceived of the study, participated in its design and coordination, performed the statistical analysis and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Project administration|Writing - Original Draft	YES
4412481	25918847	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412481	25918847	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412481	25918847	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412481	25918847	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412481	25918847	JH	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4412481	25918847	JH	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412481	25918847	JML	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412481	25918847	JML	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4412481	25918847	LW	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412481	25918847	QHZ	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4412481	25918847	QHZ	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412481	25918847	SGG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4412481	25918847	SGG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412481	25918847	WLY	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4412481	25918847	WLY	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4412481	25918847	XFS	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412481	25918847	XFS	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412481	25918847	XGS	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412481	25918847	XGS	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4412481	25918847	XS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412481	25918847	XS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412481	25918847	XS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412481	25918847	XS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4581504	26448933	Joo-Ho Shin	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
4581504	26448933	Yunjong Lee	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
5223316	28217297	GHX	2	designed and revised it	designed and revised it	Conceived and designed the experiments|Wrote the paper	Writing - Review & Editing	YES
5223316	28217297	HF	2	designed and revised it	designed and revised it	Conceived and designed the experiments|Wrote the paper	Writing - Review & Editing	YES
5223316	28217297	SLH	2	searched the literature, analyzed the data, designed and wrote this paper	searched the literature, analyzed the data, designed and wrote this paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
2825211	20205834	AC	2	collected the data	collected the data	Performed the experiments	Investigation	YES
2825211	20205834	AHLC	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
2825211	20205834	AHLJ	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
2825211	20205834	All authors	2	have read and approved the final manuscript	have read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
2825211	20205834	BG	2	designed the study|conducted data analysis|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
2825211	20205834	BG	2	designed the study|conducted data analysis|wrote the manuscript	conducted data analysis	Analyzed the data	Formal analysis	YES
2825211	20205834	BG	2	designed the study|conducted data analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
2825211	20205834	HR	2	is the principal investigator of the project|designed the study|collected the data|conducted data analysis|wrote the manuscript	is the principal investigator of the project	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
2825211	20205834	HR	2	is the principal investigator of the project|designed the study|collected the data|conducted data analysis|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
2825211	20205834	HR	2	is the principal investigator of the project|designed the study|collected the data|conducted data analysis|wrote the manuscript	collected the data	Performed the experiments	Investigation	YES
2825211	20205834	HR	2	is the principal investigator of the project|designed the study|collected the data|conducted data analysis|wrote the manuscript	conducted data analysis	Analyzed the data	Formal analysis	YES
2825211	20205834	HR	2	is the principal investigator of the project|designed the study|collected the data|conducted data analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
2825211	20205834	MM	2	collected the data	collected the data	Performed the experiments	Investigation	YES
5684672	29170676	BW	PLoS52	assisted with revising the draft manuscript	assisted with revising the draft manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5684672	29170676	SQ	PLoS52	conceived the ideas and designed methodology|assisted with revising the draft manuscript	conceived the ideas and designed methodology	Conceived and designed the experiments|Performed the experiments	Conceptualization|Methodology	YES
5684672	29170676	SQ	PLoS52	conceived the ideas and designed methodology|assisted with revising the draft manuscript	assisted with revising the draft manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5684672	29170676	WS	PLoS52	conceived the ideas and designed methodology|collected the data|analyzed the data|led the writing of the manuscript	conceived the ideas and designed methodology	Conceived and designed the experiments|Performed the experiments	Conceptualization|Methodology	YES
5684672	29170676	WS	PLoS52	conceived the ideas and designed methodology|collected the data|analyzed the data|led the writing of the manuscript	collected the data	Performed the experiments	Investigation	YES
5684672	29170676	WS	PLoS52	conceived the ideas and designed methodology|collected the data|analyzed the data|led the writing of the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5684672	29170676	WS	PLoS52	conceived the ideas and designed methodology|collected the data|analyzed the data|led the writing of the manuscript	led the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5684672	29170676	YB	PLoS52	analyzed the data|assisted with revising the draft manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5684672	29170676	YB	PLoS52	analyzed the data|assisted with revising the draft manuscript	assisted with revising the draft manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5684672	29170676	YZ	PLoS52	conceived the ideas and designed methodology|assisted with revising the draft manuscript	conceived the ideas and designed methodology	Conceived and designed the experiments|Performed the experiments	Conceptualization|Methodology	YES
5684672	29170676	YZ	PLoS52	conceived the ideas and designed methodology|assisted with revising the draft manuscript	assisted with revising the draft manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5684672	29170676	ZL	PLoS52	collected the data	collected the data	Performed the experiments	Investigation	YES
5265228	28120177	AV	2	recruited and imaged the database participants	recruited and imaged the database participants	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Investigation|Software|Visualization	YES
5265228	28120177	All authors	2	reviewed and approved the final manuscript	reviewed and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5265228	28120177	JB	2	recruited and imaged the database participants	recruited and imaged the database participants	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Investigation|Software|Visualization	YES
5265228	28120177	JCD	2	contributed to the design, recruitment, and writing of the manuscript	contributed to the design, recruitment, and writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5265228	28120177	JD	2	recruited and imaged the database participants	recruited and imaged the database participants	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Investigation|Software|Visualization	YES
5265228	28120177	KT	2	recruited and imaged the database participants	recruited and imaged the database participants	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Investigation|Software|Visualization	YES
5265228	28120177	KVL	2	recruited and imaged the database participants	recruited and imaged the database participants	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Investigation|Software|Visualization	YES
5265228	28120177	LTB	2	contributed to the design, recruitment, and writing of the manuscript	contributed to the design, recruitment, and writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5265228	28120177	MP	2	recruited and imaged the database participants	recruited and imaged the database participants	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Investigation|Software|Visualization	YES
5265228	28120177	MZ	2	recruited and imaged the database participants	recruited and imaged the database participants	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Investigation|Software|Visualization	YES
5265228	28120177	OLK	2	recruited and imaged the database participants	recruited and imaged the database participants	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Investigation|Software|Visualization	YES
5265228	28120177	SAN	2	recruited and imaged the database participants	recruited and imaged the database participants	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Investigation|Software|Visualization	YES
5265228	28120177	SH	2	recruited and imaged the database participants	recruited and imaged the database participants	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Investigation|Software|Visualization	YES
5265228	28120177	SM	2	recruited and imaged the database participants	recruited and imaged the database participants	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Investigation|Software|Visualization	YES
5265228	28120177	TS	2	acquired all of the data for system characterisation	acquired all of the data for system characterisation	Performed the experiments	Investigation	YES
5265228	28120177	TVB	2	recruited and imaged the database participants	recruited and imaged the database participants	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Investigation|Software|Visualization	YES
4412492	25918850	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412492	25918850	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412492	25918850	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412492	25918850	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412492	25918850	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412492	25918850	JYW	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412492	25918850	MX	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412492	25918850	MX	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4412492	25918850	WZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412492	25918850	WZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412492	25918850	WZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412492	25918850	WZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412492	25918850	YFM	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412492	25918850	YFM	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412492	25918850	YW	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412492	25918850	YW	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4412492	25918850	ZG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412492	25918850	ZG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412492	25918850	ZG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412492	25918850	ZG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1853235	17476337	FP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1853235	17476337	FP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1853235	17476337	FP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1853235	17476337	FP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1853235	17476337	MS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1853235	17476337	MS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1853235	17476337	MS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1853235	17476337	TB	PLoS5	Performed the experiments|Analyzed the data|Performed the ex vivo whole blood assays	Performed the experiments	Performed the experiments	Investigation	YES
1853235	17476337	TB	PLoS5	Performed the experiments|Analyzed the data|Performed the ex vivo whole blood assays	Analyzed the data	Analyzed the data	Formal analysis	YES
1853235	17476337	TB	PLoS5	Performed the experiments|Analyzed the data|Performed the ex vivo whole blood assays	Performed the ex vivo whole blood assays	Performed the experiments	Investigation	YES
5549386	28789614	DX	PLoS52	performed the experiments|edited and revised the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5549386	28789614	DX	PLoS52	performed the experiments|edited and revised the manuscript	edited and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5549386	28789614	LC	PLoS52	performed the pakchoi cultivation and sample collection	performed the pakchoi cultivation and sample collection	Performed the experiments	Investigation	YES
5549386	28789614	LD	PLoS52	performed the pakchoi cultivation and sample collection	performed the pakchoi cultivation and sample collection	Performed the experiments	Investigation	YES
5549386	28789614	SG	PLoS52	designed the experiments|edited and revised the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5549386	28789614	SG	PLoS52	designed the experiments|edited and revised the manuscript	edited and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5549386	28789614	XS	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5549386	28789614	YR	PLoS52	designed the experiments|performed the pakchoi cultivation and sample collection|performed the experiments|wrote the manuscript draft	designed the experiments	Conceived and designed the experiments	Methodology	YES
5549386	28789614	YR	PLoS52	designed the experiments|performed the pakchoi cultivation and sample collection|performed the experiments|wrote the manuscript draft	performed the pakchoi cultivation and sample collection	Performed the experiments	Investigation	YES
5549386	28789614	YR	PLoS52	designed the experiments|performed the pakchoi cultivation and sample collection|performed the experiments|wrote the manuscript draft	performed the experiments	Performed the experiments	Investigation	YES
5549386	28789614	YR	PLoS52	designed the experiments|performed the pakchoi cultivation and sample collection|performed the experiments|wrote the manuscript draft	wrote the manuscript draft	Wrote the paper	Writing - Original Draft	YES
2837615	20178632	DLG	2	contributed to the drafting and revising of the manuscript, and gave final approval of the version to be published	contributed to the drafting and revising of the manuscript, and gave final approval of the version to be published	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
2837615	20178632	KHM	2	contributed to the design of the study and gave final approval of the version to be published	contributed to the design of the study and gave final approval of the version to be published	Conceived and designed the experiments	Methodology	YES
2837615	20178632	MS	2	contributed to the acquisition of data as well as the drafting and revising of the manuscript	contributed to the acquisition of data as well as the drafting and revising of the manuscript	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
2837615	20178632	SMA	2	conceived of and designed this study, contributed to the acquisition, analysis and interpretation of data, led the drafting and revising of the manuscript, and gave final approval of the version to be published	conceived of and designed this study, contributed to the acquisition, analysis and interpretation of data, led the drafting and revising of the manuscript, and gave final approval of the version to be published	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5402342	28480026	JPL	1	Concept and design of study or acquisition of data or analysis and interpretation of data|Drafting the article or revising it critically for important intellectual content|Final approval of the version to be published	Concept and design of study or acquisition of data or analysis and interpretation of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation|Methodology	YES
5402342	28480026	JPL	1	Concept and design of study or acquisition of data or analysis and interpretation of data|Drafting the article or revising it critically for important intellectual content|Final approval of the version to be published	Drafting the article or revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5402342	28480026	JPL	1	Concept and design of study or acquisition of data or analysis and interpretation of data|Drafting the article or revising it critically for important intellectual content|Final approval of the version to be published	Final approval of the version to be published	-	-	NO
5402342	28480026	JWC	1	Concept and design of study or acquisition of data or analysis and interpretation of data|Drafting the article or revising it critically for important intellectual content|Final approval of the version to be published	Concept and design of study or acquisition of data or analysis and interpretation of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation|Methodology	YES
5402342	28480026	JWC	1	Concept and design of study or acquisition of data or analysis and interpretation of data|Drafting the article or revising it critically for important intellectual content|Final approval of the version to be published	Drafting the article or revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5402342	28480026	JWC	1	Concept and design of study or acquisition of data or analysis and interpretation of data|Drafting the article or revising it critically for important intellectual content|Final approval of the version to be published	Final approval of the version to be published	-	-	NO
5402342	28480026	LAB	1	Concept and design of study or acquisition of data or analysis and interpretation of data|Concept and design of study or acquisition of data or analysis and interpretation of data|Drafting the article or revising it critically for important intellectual content|Drafting the article or revising it critically for important intellectual content|Final approval of the version to be published|Final approval of the version to be published	Concept and design of study or acquisition of data or analysis and interpretation of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation|Methodology	YES
5402342	28480026	LAB	1	Concept and design of study or acquisition of data or analysis and interpretation of data|Concept and design of study or acquisition of data or analysis and interpretation of data|Drafting the article or revising it critically for important intellectual content|Drafting the article or revising it critically for important intellectual content|Final approval of the version to be published|Final approval of the version to be published	Concept and design of study or acquisition of data or analysis and interpretation of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation|Methodology	YES
5402342	28480026	LAB	1	Concept and design of study or acquisition of data or analysis and interpretation of data|Concept and design of study or acquisition of data or analysis and interpretation of data|Drafting the article or revising it critically for important intellectual content|Drafting the article or revising it critically for important intellectual content|Final approval of the version to be published|Final approval of the version to be published	Drafting the article or revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5402342	28480026	LAB	1	Concept and design of study or acquisition of data or analysis and interpretation of data|Concept and design of study or acquisition of data or analysis and interpretation of data|Drafting the article or revising it critically for important intellectual content|Drafting the article or revising it critically for important intellectual content|Final approval of the version to be published|Final approval of the version to be published	Drafting the article or revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5402342	28480026	LAB	1	Concept and design of study or acquisition of data or analysis and interpretation of data|Concept and design of study or acquisition of data or analysis and interpretation of data|Drafting the article or revising it critically for important intellectual content|Drafting the article or revising it critically for important intellectual content|Final approval of the version to be published|Final approval of the version to be published	Final approval of the version to be published	-	-	NO
5402342	28480026	LAB	1	Concept and design of study or acquisition of data or analysis and interpretation of data|Concept and design of study or acquisition of data or analysis and interpretation of data|Drafting the article or revising it critically for important intellectual content|Drafting the article or revising it critically for important intellectual content|Final approval of the version to be published|Final approval of the version to be published	Final approval of the version to be published	-	-	NO
5402342	28480026	NN	1	Concept and design of study or acquisition of data or analysis and interpretation of data|Drafting the article or revising it critically for important intellectual content|Final approval of the version to be published	Concept and design of study or acquisition of data or analysis and interpretation of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation|Methodology	YES
5402342	28480026	NN	1	Concept and design of study or acquisition of data or analysis and interpretation of data|Drafting the article or revising it critically for important intellectual content|Final approval of the version to be published	Drafting the article or revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5402342	28480026	NN	1	Concept and design of study or acquisition of data or analysis and interpretation of data|Drafting the article or revising it critically for important intellectual content|Final approval of the version to be published	Final approval of the version to be published	-	-	NO
5402342	28480026	YS	1	Concept and design of study or acquisition of data or analysis and interpretation of data|Drafting the article or revising it critically for important intellectual content|Final approval of the version to be published	Concept and design of study or acquisition of data or analysis and interpretation of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation|Methodology	YES
5402342	28480026	YS	1	Concept and design of study or acquisition of data or analysis and interpretation of data|Drafting the article or revising it critically for important intellectual content|Final approval of the version to be published	Drafting the article or revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5402342	28480026	YS	1	Concept and design of study or acquisition of data or analysis and interpretation of data|Drafting the article or revising it critically for important intellectual content|Final approval of the version to be published	Final approval of the version to be published	-	-	NO
5272853	28130689	CNN	2	calculated the texture features and collected the validation results of all tested methods	calculated the texture features and collected the validation results of all tested methods	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Validation	YES
5272853	28130689	HW	2	together developed the study concept|programmed the methods for cross-validation and diagnostic feature calculation, and wrote the manuscript	together developed the study concept	Conceived and designed the experiments	Conceptualization	YES
5272853	28130689	HW	2	together developed the study concept|programmed the methods for cross-validation and diagnostic feature calculation, and wrote the manuscript	programmed the methods for cross-validation and diagnostic feature calculation, and wrote the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Software|Validation|Writing - Original Draft	YES
5272853	28130689	LY	2	together developed the study concept|collected the patient images, made the doctor diagnosis, conducted the pathology analysis, specified the lymph node center, and performed image segmentation|also critically reviewed the manuscript	together developed the study concept	Conceived and designed the experiments	Conceptualization	YES
5272853	28130689	LY	2	together developed the study concept|collected the patient images, made the doctor diagnosis, conducted the pathology analysis, specified the lymph node center, and performed image segmentation|also critically reviewed the manuscript	collected the patient images, made the doctor diagnosis, conducted the pathology analysis, specified the lymph node center, and performed image segmentation	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
5272853	28130689	LY	2	together developed the study concept|collected the patient images, made the doctor diagnosis, conducted the pathology analysis, specified the lymph node center, and performed image segmentation|also critically reviewed the manuscript	also critically reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5272853	28130689	PL	2	collected the patient images, made the doctor diagnosis, conducted the pathology analysis, specified the lymph node center, and performed image segmentation	collected the patient images, made the doctor diagnosis, conducted the pathology analysis, specified the lymph node center, and performed image segmentation	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
5272853	28130689	WL	2	together developed the study concept|prepared the data samples	together developed the study concept	Conceived and designed the experiments	Conceptualization	YES
5272853	28130689	WL	2	together developed the study concept|prepared the data samples	prepared the data samples	Performed the experiments	Investigation	YES
5272853	28130689	WW	2	collected the patient images, made the doctor diagnosis, conducted the pathology analysis, specified the lymph node center, and performed image segmentation	collected the patient images, made the doctor diagnosis, conducted the pathology analysis, specified the lymph node center, and performed image segmentation	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
5272853	28130689	YL	2	collected the patient images, made the doctor diagnosis, conducted the pathology analysis, specified the lymph node center, and performed image segmentation	collected the patient images, made the doctor diagnosis, conducted the pathology analysis, specified the lymph node center, and performed image segmentation	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
4412494	25919667	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412494	25919667	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412494	25919667	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412494	25919667	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412494	25919667	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412494	25919667	BA	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412494	25919667	BA	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412494	25919667	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412494	25919667	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412494	25919667	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412494	25919667	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412494	25919667	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412494	25919667	MM	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412494	25919667	MM	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2845094	20222976	AB	2	developed the concept of the study, contributed to its design, data collection, statistical analysis, and manuscript preparation	developed the concept of the study, contributed to its design, data collection, statistical analysis, and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
2845094	20222976	AM	2	provided background work for the manuscript and contributed to its preparation	provided background work for the manuscript and contributed to its preparation	Wrote the paper	Writing - Original Draft	YES
2845094	20222976	MG	2	provided background work for the manuscript and contributed to its preparation	provided background work for the manuscript and contributed to its preparation	Wrote the paper	Writing - Original Draft	YES
2845094	20222976	SK	2	contributed in the design of the study, data collection, and manuscript preparation	contributed in the design of the study, data collection, and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Methodology|Resources|Writing - Original Draft	YES
2845094	20222976	WK	2	contributed in the design of the study, data collection, and manuscript preparation	contributed in the design of the study, data collection, and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Methodology|Resources|Writing - Original Draft	YES
5550956	28793878	AC	2	designed the research and wrote the manuscript|performed the research	designed the research and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5550956	28793878	AC	2	designed the research and wrote the manuscript|performed the research	performed the research	Performed the experiments	Investigation	YES
5550956	28793878	LD	2	designed the research and wrote the manuscript	designed the research and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5550956	28793878	MHM	2	designed the research and wrote the manuscript|performed the research	designed the research and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5550956	28793878	MHM	2	designed the research and wrote the manuscript|performed the research	performed the research	Performed the experiments	Investigation	YES
5550956	28793878	MP	2	designed the research and wrote the manuscript	designed the research and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5402343	28480028	All authors	2	have made significant contributions in the formulation of study concept and design and gathering of related literature|aproved and read the final version of this manuscript for publication	have made significant contributions in the formulation of study concept and design and gathering of related literature	Conceived and designed the experiments	Conceptualization|Methodology	YES
5402343	28480028	All authors	2	have made significant contributions in the formulation of study concept and design and gathering of related literature|aproved and read the final version of this manuscript for publication	aproved and read the final version of this manuscript for publication	-	-	NO
5684833	29170674	AM	2	analyzed and interpreted data, designed and performed the experiments, wrote and revised the manuscript	analyzed and interpreted data, designed and performed the experiments, wrote and revised the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5684833	29170674	All authors	2	contributed to the discussion and approved the final manuscript	contributed to the discussion and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5684833	29170674	MM	2	conceived of the work and generated the rna seq data	conceived of the work and generated the rna seq data	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5684833	29170674	MS	2	conceived of the work, analyzed data, wrote and revised the manuscript	conceived of the work, analyzed data, wrote and revised the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5684833	29170674	RH	2	acquired and interpreted data	acquired and interpreted data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
1853236	17476328	CA	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1853236	17476328	CA	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1853236	17476328	CB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1853236	17476328	CB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1853236	17476328	CB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1853236	17476328	CB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1853236	17476328	CF	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1853236	17476328	CL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1853236	17476328	CL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1853236	17476328	DC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1853236	17476328	DC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1853236	17476328	DM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1853236	17476328	DM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1853236	17476328	DM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1853236	17476328	EV	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1853236	17476328	EV	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1853236	17476328	EV	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1853236	17476328	EV	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1853236	17476328	FW	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1853236	17476328	FW	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1853236	17476328	GA	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1853236	17476328	JB	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1853236	17476328	JB	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1853236	17476328	JC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1853236	17476328	JC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1853236	17476328	JN	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1853236	17476328	JN	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1853236	17476328	LA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1853236	17476328	LA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1853236	17476328	LA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1853236	17476328	LO	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1853236	17476328	LO	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1853236	17476328	MR	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1853236	17476328	MR	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1853236	17476328	OH	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1853236	17476328	PB	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1853236	17476328	PC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1853236	17476328	SR	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1853236	17476328	SR	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1853236	17476328	SR	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1853236	17476328	SR	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4070026	24995149	CC	2	conducted experiments	conducted experiments	Performed the experiments	Investigation	YES
4070026	24995149	IAD	2	conducted experiments	conducted experiments	Performed the experiments	Investigation	YES
4070026	24995149	MC	2	conducted experiments	conducted experiments	Performed the experiments	Investigation	YES
4070026	24995149	MM	2	conceived experiments|conducted experiments|analyzed data|wrote the manuscript	conceived experiments	Conceived and designed the experiments	Conceptualization	YES
4070026	24995149	MM	2	conceived experiments|conducted experiments|analyzed data|wrote the manuscript	conducted experiments	Performed the experiments	Investigation	YES
4070026	24995149	MM	2	conceived experiments|conducted experiments|analyzed data|wrote the manuscript	analyzed data	Analyzed the data	Formal analysis	YES
4070026	24995149	MM	2	conceived experiments|conducted experiments|analyzed data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4070026	24995149	MT	2	conceived experiments|wrote the manuscript	conceived experiments	Conceived and designed the experiments	Conceptualization	YES
4070026	24995149	MT	2	conceived experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
2851582	20181080	ADF	2	oversaw all aspects of study including recruitment, data/specimen analysis, and manuscript preparation	oversaw all aspects of study including recruitment, data/specimen analysis, and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Supervision|Writing - Original Draft	YES
2851582	20181080	AMG	2	oversaw all aspects of study including recruitment, data/specimen analysis, and manuscript preparation	oversaw all aspects of study including recruitment, data/specimen analysis, and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Supervision|Writing - Original Draft	YES
2851582	20181080	BK	2	were co-authors, assisting with data analysis	were co-authors, assisting with data analysis	Analyzed the data	Formal analysis	YES
2851582	20181080	BLB	2	were co-authors, assisting with data analysis	were co-authors, assisting with data analysis	Analyzed the data	Formal analysis	YES
2851582	20181080	CMM	2	were co-authors, assisting with data analysis	were co-authors, assisting with data analysis	Analyzed the data	Formal analysis	YES
2851582	20181080	JK	2	oversaw all aspects of study including recruitment, data/specimen analysis, and manuscript preparation	oversaw all aspects of study including recruitment, data/specimen analysis, and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Supervision|Writing - Original Draft	YES
2851582	20181080	JRH	2	was the primary investigator, obtained grant funds for project, designed study, supervised all study recruitment, data/specimen analysis, statistical analysis and manuscript preparation	was the primary investigator, obtained grant funds for project, designed study, supervised all study recruitment, data/specimen analysis, statistical analysis and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Funding acquisition|Investigation|Methodology|Supervision|Writing - Original Draft	YES
2851582	20181080	LLH	2	were co-authors, assisting with data analysis	were co-authors, assisting with data analysis	Analyzed the data	Formal analysis	YES
2851582	20181080	LMY	2	were co-authors, assisting with data analysis	were co-authors, assisting with data analysis	Analyzed the data	Formal analysis	YES
2851582	20181080	MS	2	oversaw all aspects of study including recruitment, data/specimen analysis, and manuscript preparation	oversaw all aspects of study including recruitment, data/specimen analysis, and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Supervision|Writing - Original Draft	YES
2851582	20181080	NAR	2	oversaw all aspects of study including recruitment, data/specimen analysis, and manuscript preparation	oversaw all aspects of study including recruitment, data/specimen analysis, and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Supervision|Writing - Original Draft	YES
2851582	20181080	NK	2	oversaw all aspects of study including recruitment, data/specimen analysis, and manuscript preparation	oversaw all aspects of study including recruitment, data/specimen analysis, and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Supervision|Writing - Original Draft	YES
2851582	20181080	SA	2	oversaw all aspects of study including recruitment, data/specimen analysis, and manuscript preparation	oversaw all aspects of study including recruitment, data/specimen analysis, and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Supervision|Writing - Original Draft	YES
2851582	20181080	SLR	2	oversaw all aspects of study including recruitment, data/specimen analysis, and manuscript preparation	oversaw all aspects of study including recruitment, data/specimen analysis, and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Supervision|Writing - Original Draft	YES
4412496	25919289	BH	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412496	25919289	GL	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412496	25919289	GL	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412496	25919289	GL	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412496	25919289	JG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4412496	25919289	JS	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412496	25919289	JY	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4412496	25919289	JY	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412496	25919289	MF	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412496	25919289	MF	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412496	25919289	SF	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412496	25919289	TA	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412496	25919289	TA	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412496	25919289	WC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4412496	25919289	WC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412496	25919289	YL	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5402344	28480029	AM	2	performed the experimental work and did the data collection|performed the statistical analysis|did the final data interpretation|contributed to the conception and design of the study	performed the experimental work and did the data collection	Performed the experiments	Investigation	YES
5402344	28480029	AM	2	performed the experimental work and did the data collection|performed the statistical analysis|did the final data interpretation|contributed to the conception and design of the study	performed the statistical analysis	Analyzed the data	Formal analysis	YES
5402344	28480029	AM	2	performed the experimental work and did the data collection|performed the statistical analysis|did the final data interpretation|contributed to the conception and design of the study	did the final data interpretation	Analyzed the data	Formal analysis	YES
5402344	28480029	AM	2	performed the experimental work and did the data collection|performed the statistical analysis|did the final data interpretation|contributed to the conception and design of the study	contributed to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5402344	28480029	APN	2	did the final data interpretation|contributed to the conception and design of the study	did the final data interpretation	Analyzed the data	Formal analysis	YES
5402344	28480029	APN	2	did the final data interpretation|contributed to the conception and design of the study	contributed to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5402344	28480029	All co-authors	2	revised and approved the paper for publication	revised and approved the paper for publication	Wrote the paper	Writing - Review & Editing	YES
5402344	28480029	BMV	2	did the final data interpretation|contributed to the conception and design of the study	did the final data interpretation	Analyzed the data	Formal analysis	YES
5402344	28480029	BMV	2	did the final data interpretation|contributed to the conception and design of the study	contributed to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5402344	28480029	DEVR	2	did the final data interpretation	did the final data interpretation	Analyzed the data	Formal analysis	YES
5402344	28480029	DS	2	performed and interpreted the multiplex cytokine analysis	performed and interpreted the multiplex cytokine analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5402344	28480029	DVR	2	contributed to the conception and design of the study	contributed to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5402344	28480029	GF	2	contributed to the conception and design of the study	contributed to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5402344	28480029	GMV	2	did the final data interpretation|contributed to the conception and design of the study	did the final data interpretation	Analyzed the data	Formal analysis	YES
5402344	28480029	GMV	2	did the final data interpretation|contributed to the conception and design of the study	contributed to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5402344	28480029	IK	2	contributed to the conception and design of the study	contributed to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5402344	28480029	MC	2	contributed to the conception and design of the study	contributed to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5402344	28480029	RV	2	did the final data interpretation|contributed to the conception and design of the study	did the final data interpretation	Analyzed the data	Formal analysis	YES
5402344	28480029	RV	2	did the final data interpretation|contributed to the conception and design of the study	contributed to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5402344	28480029	SC	2	performed and interpreted the multiplex cytokine analysis	performed and interpreted the multiplex cytokine analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5402344	28480029	SEV	2	performed the statistical analysis|contributed to the conception and design of the study	performed the statistical analysis	Analyzed the data	Formal analysis	YES
5402344	28480029	SEV	2	performed the statistical analysis|contributed to the conception and design of the study	contributed to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5402344	28480029	SO	2	performed the experimental work and did the data collection	performed the experimental work and did the data collection	Performed the experiments	Investigation	YES
5686044	29176987	EB	2	of the program and headed the research direction and guidance	of the program and headed the research direction and guidance	-	Supervision	YES
5686044	29176987	LR	2	assisted in research direction and guidance, and carried out the ams measurements	assisted in research direction and guidance, and carried out the ams measurements	Performed the experiments	Investigation|Supervision	YES
5686044	29176987	PI	2	of the program and headed the research direction and guidance	of the program and headed the research direction and guidance	-	Supervision	YES
5686044	29176987	Ph.D.	2	assisted in research direction and guidance, and carried out the ams measurements	assisted in research direction and guidance, and carried out the ams measurements	Performed the experiments	Investigation|Supervision	YES
5686044	29176987	ZK	2	obtained the sample on which the research was carried out	obtained the sample on which the research was carried out	Performed the experiments	Investigation	YES
5293699	28168589	All authors	2	contributed to the literature research and statistical analysis	contributed to the literature research and statistical analysis	Analyzed the data	Formal analysis	YES
5293699	28168589	BN	2	contributed to the study concepts and study design|contributed to the data acquisition and analysis|contributed to the manuscript drafting and editing	contributed to the study concepts and study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5293699	28168589	BN	2	contributed to the study concepts and study design|contributed to the data acquisition and analysis|contributed to the manuscript drafting and editing	contributed to the data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5293699	28168589	BN	2	contributed to the study concepts and study design|contributed to the data acquisition and analysis|contributed to the manuscript drafting and editing	contributed to the manuscript drafting and editing	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5293699	28168589	FB	2	contributed to the study concepts and study design|contributed to the data acquisition and analysis|contributed to the manuscript drafting and editing	contributed to the study concepts and study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5293699	28168589	FB	2	contributed to the study concepts and study design|contributed to the data acquisition and analysis|contributed to the manuscript drafting and editing	contributed to the data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5293699	28168589	FB	2	contributed to the study concepts and study design|contributed to the data acquisition and analysis|contributed to the manuscript drafting and editing	contributed to the manuscript drafting and editing	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5293699	28168589	KAdS	2	contributed to the data acquisition and analysis	contributed to the data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5293699	28168589	LS	2	contributed to the study concepts and study design|contributed to the data acquisition and analysis|contributed to the manuscript drafting and editing	contributed to the study concepts and study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5293699	28168589	LS	2	contributed to the study concepts and study design|contributed to the data acquisition and analysis|contributed to the manuscript drafting and editing	contributed to the data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5293699	28168589	LS	2	contributed to the study concepts and study design|contributed to the data acquisition and analysis|contributed to the manuscript drafting and editing	contributed to the manuscript drafting and editing	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4077001	25006539	MALDI-TOF	2	sequencing, elucidated lipopeptide structure and helped to draft manuscript	sequencing, elucidated lipopeptide structure and helped to draft manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4077001	25006539	MS	2	sequencing, elucidated lipopeptide structure and helped to draft manuscript	sequencing, elucidated lipopeptide structure and helped to draft manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5327758	28286521	Julie E. Morgan	2	performed all experiments within the paper	performed all experiments within the paper	Performed the experiments	Investigation	YES
5402345	28480030	CPR	2	that was purchased, and participated in writing the manuscript	that was purchased, and participated in writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5402345	28480030	DV	2	conceived, performed and analyzed the experiments shown in figures and tables, and participated in writing the manuscript	conceived, performed and analyzed the experiments shown in figures and tables, and participated in writing the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Visualization|Writing - Original Draft	YES
5402345	28480030	KN	2	conceived and analyzed the experiments shown in figures and tables, and was responsible for the manuscript	conceived and analyzed the experiments shown in figures and tables, and was responsible for the manuscript	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Visualization	YES
5402345	28480030	ZJ	2	supervised the preparation of recombinant enzymes, and participated in writing the manuscript	supervised the preparation of recombinant enzymes, and participated in writing the manuscript	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Original Draft	YES
1853237	17476330	KE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1853237	17476330	KE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1853237	17476330	KE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1853237	17476330	KE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1853237	17476330	KE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1853237	17476330	MS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1853237	17476330	MS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1853237	17476330	MS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1853237	17476330	MS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1853237	17476330	MY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1853237	17476330	MY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1853237	17476330	MY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1853237	17476330	MY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1853237	17476330	MY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1853237	17476330	TT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1853237	17476330	TT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1853237	17476330	TT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1853237	17476330	TT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5551008	28793853	BAM	2	contributed to study design, performed rna seq data analysis and contributed to writing the manuscript	contributed to study design, performed rna seq data analysis and contributed to writing the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
5551008	28793853	CLM	2	was involved in phenotyping and sample collection	was involved in phenotyping and sample collection	Performed the experiments	Investigation	YES
5551008	28793853	DEM	2	contributed to study design and manuscript preparation	contributed to study design and manuscript preparation	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5551008	28793853	EWH	2	conceived and designed the study, was involved in phenotyping and sample collection and contributed to results interpretation and writing the manuscript	conceived and designed the study, was involved in phenotyping and sample collection and contributed to results interpretation and writing the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5551008	28793853	GF	2	was involved in sample collection, prepared the samples and contributed to rna seq analysis	was involved in sample collection, prepared the samples and contributed to rna seq analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5551008	28793853	KB	2	performed the downstream bioinformatics analysis, interpreted results and wrote the manuscript	performed the downstream bioinformatics analysis, interpreted results and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5551008	28793853	KFG	2	was involved in phenotyping and sample collection	was involved in phenotyping and sample collection	Performed the experiments	Investigation	YES
5551008	28793853	LMK	2	designed the study, coordinated phenotyping and sample collection and contributed to manuscript preparation	designed the study, coordinated phenotyping and sample collection and contributed to manuscript preparation	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Project administration|Writing - Original Draft	YES
5551008	28793853	PAM	2	contributed to study design and implemented an rna seq data pre-processing pipeline	contributed to study design and implemented an rna seq data pre-processing pipeline	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Investigation|Methodology|Resources	YES
5402346	28480031	JLH	PLoS52	gave the suggestions	gave the suggestions	-	-	NO
5402346	28480031	LQ	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5402346	28480031	NZ	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5402346	28480031	XQY	PLoS52	revised the language	revised the language	Wrote the paper	Writing - Review & Editing	YES
5296268	28176243	AMP	2	obtained the ethical approval, designed the study, analysed the data and co-wrote paper	obtained the ethical approval, designed the study, analysed the data and co-wrote paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Project administration|Writing - Original Draft	YES
5296268	28176243	CDA	2	co-wrote the paper	co-wrote the paper	Wrote the paper	Writing - Original Draft	YES
5296268	28176243	GK	2	designed the study, consented the patients, acquired the data and analysed the data	designed the study, consented the patients, acquired the data and analysed the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
4412497	25919292	HA	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4412497	25919292	HA	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412497	25919292	HH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412497	25919292	HH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412497	25919292	HH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412497	25919292	HH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412497	25919292	HH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412497	25919292	HZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412497	25919292	HZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412497	25919292	HZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412497	25919292	HZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412497	25919292	JZ	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4412497	25919292	LG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4412497	25919292	ML	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412497	25919292	ML	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412497	25919292	ML	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412497	25919292	MZ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412497	25919292	MZ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412497	25919292	MZ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412497	25919292	PE	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4412497	25919292	XP	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412497	25919292	XP	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412497	25919292	XW	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412497	25919292	YY	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5686053	29176989	GN	2	participated in the design of the study, collection of the data, discussion and interpretation of the results	participated in the design of the study, collection of the data, discussion and interpretation of the results	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5686053	29176989	LO	2	participated in the design of the study, collection of the data, discussion and interpretation of the results	participated in the design of the study, collection of the data, discussion and interpretation of the results	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5686053	29176989	LZ	2	participated in the design of the study, collection of the data, discussion and interpretation of the results	participated in the design of the study, collection of the data, discussion and interpretation of the results	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5686053	29176989	PZ	2	participated in the design of the study, analysis the data and revision of the manuscript	participated in the design of the study, analysis the data and revision of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
5686053	29176989	QY	2	participated in the design of the study, collection of the data, discussion and interpretation of the results	participated in the design of the study, collection of the data, discussion and interpretation of the results	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5686053	29176989	XZ	2	participated in the design of the study, carried out the experiment, collected and analyzed the data, and drafted the manuscript	participated in the design of the study, carried out the experiment, collected and analyzed the data, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5686053	29176989	YH	2	participated in the design of the study, collection of the data, discussion and interpretation of the results	participated in the design of the study, collection of the data, discussion and interpretation of the results	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5686053	29176989	ZZ	2	participated in the design of the study, collection of the data, discussion and interpretation of the results	participated in the design of the study, collection of the data, discussion and interpretation of the results	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
3819946	24235883	Yi-Ji Su	2	contributed equally to this work	contributed equally to this work	-	-	NO
3819946	24235883	Zhi-Yong Guan	2	contributed equally to this work	contributed equally to this work	-	-	NO
1853238	17476331	AS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1853238	17476331	AS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1853238	17476331	AS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1853238	17476331	IB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1853238	17476331	IB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1853238	17476331	IB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1853238	17476331	TK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1853238	17476331	TK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1853238	17476331	TK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1853238	17476331	UP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1853238	17476331	UP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1853238	17476331	UP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5402347	28480032	DXF	2	were responsible for its revision	were responsible for its revision	Wrote the paper	Writing - Review & Editing	YES
5402347	28480032	GC	2	were responsible for its drafting and revision	were responsible for its drafting and revision	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5402347	28480032	LS	2	were responsible for writing the manuscript	were responsible for writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5402347	28480032	MJ	2	were responsible for writing the manuscript	were responsible for writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5402347	28480032	RG	2	were responsible for its revision	were responsible for its revision	Wrote the paper	Writing - Review & Editing	YES
5402347	28480032	YZS	2	were responsible for its drafting and revision	were responsible for its drafting and revision	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5402347	28480032	ZQY	2	were responsible for its revision	were responsible for its revision	Wrote the paper	Writing - Review & Editing	YES
4412498	25919110	DS	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412498	25919110	EH	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412498	25919110	HB	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412498	25919110	KY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412498	25919110	KY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412498	25919110	KY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412498	25919110	KY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412498	25919110	KY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412498	25919110	PH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412498	25919110	PH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412498	25919110	PH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412498	25919110	PH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412498	25919110	PH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412498	25919110	PS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412498	25919110	PS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412498	25919110	PS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412498	25919110	PS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412498	25919110	PS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5551020	28793856	DP	PLoS52	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5551020	28793856	JS	PLoS52	performed the experiments|revised the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5551020	28793856	JS	PLoS52	performed the experiments|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5551020	28793856	JW	PLoS52	conceived and designed the experiments|drafted the manuscript|revised the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5551020	28793856	JW	PLoS52	conceived and designed the experiments|drafted the manuscript|revised the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5551020	28793856	JW	PLoS52	conceived and designed the experiments|drafted the manuscript|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5551020	28793856	JZ	PLoS52	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5551020	28793856	XY	PLoS52	performed the experiments|performed data analysis|drafted the manuscript|revised the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5551020	28793856	XY	PLoS52	performed the experiments|performed data analysis|drafted the manuscript|revised the manuscript	performed data analysis	Analyzed the data	Formal analysis	YES
5551020	28793856	XY	PLoS52	performed the experiments|performed data analysis|drafted the manuscript|revised the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5551020	28793856	XY	PLoS52	performed the experiments|performed data analysis|drafted the manuscript|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5551020	28793856	YQ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
4086442	25024928	AP	5	conceived part of the study and participated in the coordination	conceived part of the study and participated in the coordination	Conceived and designed the experiments	Conceptualization|Project administration	YES
4086442	25024928	BN	5	conceived part of the study and participated in the coordination	conceived part of the study and participated in the coordination	Conceived and designed the experiments	Conceptualization|Project administration	YES
4086442	25024928	EP	5	carried out the preparative enzymatic reactions	carried out the preparative enzymatic reactions	Performed the experiments	Investigation	YES
4086442	25024928	GA	5	carried out optimization of hemicellulose extraction from rhizome	carried out optimization of hemicellulose extraction from rhizome	Performed the experiments	Investigation	YES
4086442	25024928	GT	5	carried out activity assay	carried out activity assay	Performed the experiments	Investigation	YES
4086442	25024928	IF	5	carried out the analytical enzymatic reactions	carried out the analytical enzymatic reactions	Performed the experiments	Investigation	YES
4086442	25024928	LL	5	conceived part of the study and VC carried out microbiological studies	conceived part of the study and VC carried out microbiological studies	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
4086442	25024928	PdD	5	carried out optimization of hemicellulose extraction from rhizome	carried out optimization of hemicellulose extraction from rhizome	Performed the experiments	Investigation	YES
5313492	28210997	ET	2	participated in the design of the study and in the analysis and interpretation of data, and drafted the manuscript	participated in the design of the study and in the analysis and interpretation of data, and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5313492	28210997	FK	2	participated in the analysis and interpretation of data	participated in the analysis and interpretation of data	Analyzed the data	Formal analysis	YES
5313492	28210997	JS	2	participated in the analysis and interpretation of data	participated in the analysis and interpretation of data	Analyzed the data	Formal analysis	YES
5313492	28210997	LE	2	participated in the design of the study and in the analysis and interpretation of data, and drafted the manuscript	participated in the design of the study and in the analysis and interpretation of data, and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5313492	28210997	LS	2	participated in the design of the study and in the analysis and interpretation of data, and drafted the manuscript	participated in the design of the study and in the analysis and interpretation of data, and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5313492	28210997	MO	2	performed the statistical analyses	performed the statistical analyses	Analyzed the data	Formal analysis	YES
5313492	28210997	MP	2	participated in the analysis and interpretation of data	participated in the analysis and interpretation of data	Analyzed the data	Formal analysis	YES
5313492	28210997	MS	2	participated in the analysis and interpretation of data	participated in the analysis and interpretation of data	Analyzed the data	Formal analysis	YES
5313492	28210997	NH	2	participated in the analysis and interpretation of data	participated in the analysis and interpretation of data	Analyzed the data	Formal analysis	YES
5313492	28210997	OE	2	participated in the design of the study and in the analysis and interpretation of data, and drafted the manuscript	participated in the design of the study and in the analysis and interpretation of data, and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5313492	28210997	PHC	2	participated in the analysis and interpretation of data	participated in the analysis and interpretation of data	Analyzed the data	Formal analysis	YES
5313492	28210997	RK	2	participated in the analysis and interpretation of data	participated in the analysis and interpretation of data	Analyzed the data	Formal analysis	YES
5313492	28210997	SLB	2	participated in the design of the study and in the analysis and interpretation of data, and drafted the manuscript|performed the statistical analyses	participated in the design of the study and in the analysis and interpretation of data, and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5313492	28210997	SLB	2	participated in the design of the study and in the analysis and interpretation of data, and drafted the manuscript|performed the statistical analyses	performed the statistical analyses	Analyzed the data	Formal analysis	YES
5686318	29176986	All authors	2	contributed to discussion of the results and approved the final manuscript	contributed to discussion of the results and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5686318	29176986	C-QD	2	designed the experiments on vineyard samples	designed the experiments on vineyard samples	Conceived and designed the experiments	Methodology	YES
5686318	29176986	FH	2	revised the manuscript and provided suggestions	revised the manuscript and provided suggestions	Wrote the paper	Writing - Review & Editing	YES
5686318	29176986	GC	2	promoted the double cropping system and sampled the grapes	promoted the double cropping system and sampled the grapes	-	-	NO
5686318	29176986	JW	2	designed the experiments on vineyard samples|revised the manuscript and provided suggestions	designed the experiments on vineyard samples	Conceived and designed the experiments	Methodology	YES
5686318	29176986	JW	2	designed the experiments on vineyard samples|revised the manuscript and provided suggestions	revised the manuscript and provided suggestions	Wrote the paper	Writing - Review & Editing	YES
5686318	29176986	LH	2	provided statistical and bioinformatics analysis	provided statistical and bioinformatics analysis	Analyzed the data	Formal analysis	YES
5686318	29176986	M-MC	2	promoted the double cropping system and sampled the grapes	promoted the double cropping system and sampled the grapes	-	-	NO
5686318	29176986	MS	2	analysis, and drafted the manuscript	analysis, and drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5686318	29176986	R-RG	2	provided statistical and bioinformatics analysis	provided statistical and bioinformatics analysis	Analyzed the data	Formal analysis	YES
5686318	29176986	X-HY	2	participated in the process of flavonoid extractions	participated in the process of flavonoid extractions	-	-	NO
5686318	29176986	X-JB	2	designed the experiments on vineyard samples	designed the experiments on vineyard samples	Conceived and designed the experiments	Methodology	YES
5686318	29176986	X-JC	2	promoted the double cropping system and sampled the grapes	promoted the double cropping system and sampled the grapes	-	-	NO
5686318	29176986	YW	2	provided statistical and bioinformatics analysis	provided statistical and bioinformatics analysis	Analyzed the data	Formal analysis	YES
5402348	28480033	JMW	2	participated in the overall design of the review and wrote the manuscript	participated in the overall design of the review and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5402348	28480033	KJL	2	participated in the overall design of the review and wrote the manuscript|edited, improved, participated in the overall design of the review and obtained funding	participated in the overall design of the review and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5402348	28480033	KJL	2	participated in the overall design of the review and wrote the manuscript|edited, improved, participated in the overall design of the review and obtained funding	edited, improved, participated in the overall design of the review and obtained funding	Conceived and designed the experiments|Wrote the paper	Funding acquisition|Writing - Review & Editing	YES
2854104	20156347	AES	2	was the primary author of the manuscript and played an important role in study design, data collection and assessment	was the primary author of the manuscript and played an important role in study design, data collection and assessment	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
2854104	20156347	DHF	2	played an important role in data collection and manuscript preparation	played an important role in data collection and manuscript preparation	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
2854104	20156347	JRS	2	was the senior author and played an important role in the grant procurement, study design, data analysis and manuscript preparation	was the senior author and played an important role in the grant procurement, study design, data analysis and manuscript preparation	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
2854104	20156347	KLK	2	played an important role in data collection and manuscript preparation	played an important role in data collection and manuscript preparation	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
1853239	17476332	DB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1853239	17476332	DB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1853239	17476332	DB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1853239	17476332	DW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1853239	17476332	DW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1853239	17476332	DW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1853239	17476332	NS	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4207730	25149707	See Members	2	of the airtum working group in the appendix section	of the airtum working group in the appendix section	-	-	NO
4412524	25919299	FF	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4412524	25919299	HQY	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412524	25919299	HQY	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412524	25919299	HQY	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412524	25919299	HW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4412524	25919299	JSH	PLoS5	Contributed reagents/materials/analysis tools|Took part in discussion on manuscript writing	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412524	25919299	JSH	PLoS5	Contributed reagents/materials/analysis tools|Took part in discussion on manuscript writing	Took part in discussion on manuscript writing	Wrote the paper	Writing - Original Draft	YES
4412524	25919299	JW	PLoS5	Contributed reagents/materials/analysis tools|Took part in discussion on manuscript writing	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412524	25919299	JW	PLoS5	Contributed reagents/materials/analysis tools|Took part in discussion on manuscript writing	Took part in discussion on manuscript writing	Wrote the paper	Writing - Original Draft	YES
4412524	25919299	LLS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4412524	25919299	TH	PLoS5	Contributed reagents/materials/analysis tools|Took part in discussion on manuscript writing	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412524	25919299	TH	PLoS5	Contributed reagents/materials/analysis tools|Took part in discussion on manuscript writing	Took part in discussion on manuscript writing	Wrote the paper	Writing - Original Draft	YES
4412524	25919299	XLP	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412524	25919299	YPZ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412524	25919299	YYJ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4412524	25919299	YZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412524	25919299	YZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412524	25919299	YZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412524	25919299	YZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5402240	28487741	Fanwei Meng	2	contributed equally to the manuscript	contributed equally to the manuscript	-	-	NO
5402240	28487741	Yohan Choi	2	contributed equally to the manuscript	contributed equally to the manuscript	-	-	NO
4100562	25045602	CR-S	2	collected and analyzed the volatile organic compounds	collected and analyzed the volatile organic compounds	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4100562	25045602	JWB	2	conceived the study and participated in the drafting of the paper	conceived the study and participated in the drafting of the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4100562	25045602	RH	2	designed the volatile exposure studies	designed the volatile exposure studies	Conceived and designed the experiments	Methodology	YES
4100562	25045602	SL	2	participated in the exposure experiments and the drafting of the paper	participated in the exposure experiments and the drafting of the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4584037	26448934	Hong-Hwa Chen	2	equally contributed to this work	equally contributed to this work	-	-	NO
4584037	26448934	Keng-Liang Wu	2	equally contributed to this work	equally contributed to this work	-	-	NO
5551029	28793854	AK	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5551029	28793854	AM	PLoS52	collected the leaf materials	collected the leaf materials	Performed the experiments	Investigation	YES
5551029	28793854	HW	PLoS52	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5551029	28793854	JL	PLoS52	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5551029	28793854	LY	PLoS52	collected the leaf materials	collected the leaf materials	Performed the experiments	Investigation	YES
5551029	28793854	MM	PLoS52	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5551029	28793854	NL	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5551029	28793854	SJ	PLoS52	collected the leaf materials	collected the leaf materials	Performed the experiments	Investigation	YES
5551029	28793854	YS	PLoS52	conceived and designed the study|performed de novo assembly, genome annotation, phylogenetic and other analyses|drafted the manuscript|performed the experiments	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5551029	28793854	YS	PLoS52	conceived and designed the study|performed de novo assembly, genome annotation, phylogenetic and other analyses|drafted the manuscript|performed the experiments	performed de novo assembly, genome annotation, phylogenetic and other analyses	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5551029	28793854	YS	PLoS52	conceived and designed the study|performed de novo assembly, genome annotation, phylogenetic and other analyses|drafted the manuscript|performed the experiments	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5551029	28793854	YS	PLoS52	conceived and designed the study|performed de novo assembly, genome annotation, phylogenetic and other analyses|drafted the manuscript|performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
2860344	20331847	CLC	2	performed statistical analysis	performed statistical analysis	Analyzed the data	Formal analysis	YES
2860344	20331847	SC	2	participated in the design of the study and performed the exercise protocol	participated in the design of the study and performed the exercise protocol	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
2860344	20331847	SH	2	analyzed blood samples for glutathione levels	analyzed blood samples for glutathione levels	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
2860344	20331847	WK	2	performed the exercise testing protocol	performed the exercise testing protocol	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
2860344	20331847	ZL	2	participated in the design of the study protocol, coordination and draft of the manuscript	participated in the design of the study protocol, coordination and draft of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft	YES
5402349	28480034	JM	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5402349	28480034	ZY	2	searched the reference	searched the reference	-	-	NO
5313496	28210996	All authors	2	contributed to the writing of the article and approved the final version	contributed to the writing of the article and approved the final version	Wrote the paper	Writing - Original Draft	YES
5313496	28210996	ES	2	were the supervisors of the study	were the supervisors of the study	-	Supervision	YES
5313496	28210996	GH	2	assisted in the experiments	assisted in the experiments	Performed the experiments	Investigation	YES
5313496	28210996	HI	2	assisted in the experiments	assisted in the experiments	Performed the experiments	Investigation	YES
5313496	28210996	HK	2	assisted in the data analysis	assisted in the data analysis	Analyzed the data	Formal analysis	YES
5313496	28210996	JH	2	were the supervisors of the study	were the supervisors of the study	-	Supervision	YES
5313496	28210996	KA	2	assisted in the experiments	assisted in the experiments	Performed the experiments	Investigation	YES
5313496	28210996	KI	2	assisted in the experiments	assisted in the experiments	Performed the experiments	Investigation	YES
5313496	28210996	KM	2	assisted in the data analysis	assisted in the data analysis	Analyzed the data	Formal analysis	YES
5313496	28210996	TW	2	conducted the experiments, performed the analysis, and wrote the manuscript	conducted the experiments, performed the analysis, and wrote the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5313496	28210996	YK	2	assisted in the experiments	assisted in the experiments	Performed the experiments	Investigation	YES
1853240	17476333	BS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1853240	17476333	BS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1853240	17476333	JM	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1853240	17476333	JM	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1853240	17476333	PP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1853240	17476333	PP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1853240	17476333	PP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1853240	17476333	YO	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1853240	17476333	YO	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5686452	29176988	AMA	2	handling editor declared their shared affiliation	handling editor declared their shared affiliation	-	-	NO
5686452	29176988	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5686452	29176988	C-ED	2	supervised dl carried out the statistical analyses under the|helped cd performed the whole snp genotyping analysis and validation process with the|conceived and coordinated the study	supervised dl carried out the statistical analyses under the	Analyzed the data	Formal analysis|Supervision	YES
5686452	29176988	C-ED	2	supervised dl carried out the statistical analyses under the|helped cd performed the whole snp genotyping analysis and validation process with the|conceived and coordinated the study	helped cd performed the whole snp genotyping analysis and validation process with the	Performed the experiments	Investigation|Validation	YES
5686452	29176988	C-ED	2	supervised dl carried out the statistical analyses under the|helped cd performed the whole snp genotyping analysis and validation process with the|conceived and coordinated the study	conceived and coordinated the study	Conceived and designed the experiments	Conceptualization|Project administration	YES
5686452	29176988	CD	2	managed the leaf sample collection and part of dna extraction|performed the whole snp genotyping analysis and validation process with the	managed the leaf sample collection and part of dna extraction	Performed the experiments	Investigation	YES
5686452	29176988	CD	2	managed the leaf sample collection and part of dna extraction|performed the whole snp genotyping analysis and validation process with the	performed the whole snp genotyping analysis and validation process with the	Performed the experiments	Investigation|Validation	YES
5686452	29176988	DL	2	carried out the statistical analyses under the	carried out the statistical analyses under the	Analyzed the data	Formal analysis	YES
5686452	29176988	ER	2	managed the leaf sample collection and part of dna extraction	managed the leaf sample collection and part of dna extraction	Performed the experiments	Investigation	YES
5686452	29176988	FL	2	coordinated the eu fruitbreedomics project including this study	coordinated the eu fruitbreedomics project including this study	-	Project administration	YES
5686452	29176988	HM	2	carried out the statistical analyses under the|helped cd performed the whole snp genotyping analysis and validation process with the	carried out the statistical analyses under the	Analyzed the data	Formal analysis	YES
5686452	29176988	HM	2	carried out the statistical analyses under the|helped cd performed the whole snp genotyping analysis and validation process with the	helped cd performed the whole snp genotyping analysis and validation process with the	Performed the experiments	Investigation|Validation	YES
5686452	29176988	HN	2	critically reviewed the manuscript	critically reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5686452	29176988	JU	2	carried out the statistical analyses under the	carried out the statistical analyses under the	Analyzed the data	Formal analysis	YES
5686452	29176988	LB	2	critically reviewed the manuscript	critically reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5686452	29176988	LG-G	2	critically reviewed the manuscript	critically reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5686452	29176988	MB	2	brought expertise about gwas methodology and results interpretation|critically reviewed the manuscript	brought expertise about gwas methodology and results interpretation	Performed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5686452	29176988	MB	2	brought expertise about gwas methodology and results interpretation|critically reviewed the manuscript	critically reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5686452	29176988	MO	2	critically reviewed the manuscript	critically reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5686452	29176988	MT	2	critically reviewed the manuscript	critically reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5686452	29176988	RV	2	critically reviewed the manuscript	critically reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5686452	29176988	SM	2	brought expertise about gwas methodology and results interpretation|critically reviewed the manuscript	brought expertise about gwas methodology and results interpretation	Performed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5686452	29176988	SM	2	brought expertise about gwas methodology and results interpretation|critically reviewed the manuscript	critically reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5686452	29176988	ST	2	supervised dl carried out the statistical analyses under the	supervised dl carried out the statistical analyses under the	Analyzed the data	Formal analysis|Supervision	YES
5686452	29176988	The authors	2	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	Performed the experiments	Investigation	YES
2861014	20398312	ALW	2	was the primary investigator, supervised all study recruitment, and data collection	was the primary investigator, supervised all study recruitment, and data collection	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Supervision	YES
2861014	20398312	AMG	2	assisted with study recruitment and data collection	assisted with study recruitment and data collection	Performed the experiments	Investigation	YES
2861014	20398312	JK	2	were co-authors, oversaw all aspects of study including recruitment, data/specimen analysis, and manuscript preparation	were co-authors, oversaw all aspects of study including recruitment, data/specimen analysis, and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Supervision|Writing - Original Draft	YES
2861014	20398312	JRH	2	was involved with study design, statistical analysis, and manuscript preparation	was involved with study design, statistical analysis, and manuscript preparation	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
2861014	20398312	NAR	2	were co-authors, oversaw all aspects of study including recruitment, data/specimen analysis, and manuscript preparation	were co-authors, oversaw all aspects of study including recruitment, data/specimen analysis, and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Supervision|Writing - Original Draft	YES
4412526	25919011	FK	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412526	25919011	FK	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412526	25919011	FK	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412526	25919011	HM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412526	25919011	HM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412526	25919011	HM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412526	25919011	HS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412526	25919011	HS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412526	25919011	HS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412526	25919011	JBS	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412526	25919011	JBS	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412526	25919011	JPMF	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412526	25919011	JPMF	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412526	25919011	JPMF	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412526	25919011	KJB	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412526	25919011	KJB	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412526	25919011	MWGNS	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412526	25919011	MWGNS	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412526	25919011	RTMD	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412526	25919011	RTMD	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412526	25919011	RTMD	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4105880	25147754	DP	2	contributed in conceiving the study and revised the manuscript	contributed in conceiving the study and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
4105880	25147754	JT	2	participated in design of the study and revised the manuscript	participated in design of the study and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
4105880	25147754	LS	2	performed the experiments and commented on the manuscript	performed the experiments and commented on the manuscript	Performed the experiments	Investigation	YES
4105880	25147754	MA	2	performed the experiments and commented on the manuscript	performed the experiments and commented on the manuscript	Performed the experiments	Investigation	YES
4105880	25147754	MB	2	participated in the initial design of the study and commented the manuscript	participated in the initial design of the study and commented the manuscript	Conceived and designed the experiments	Methodology	YES
4105880	25147754	MFM	2	participated in design of the study and revised the manuscript	participated in design of the study and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
4105880	25147754	MGG	2	conceived the study and revised the manuscript	conceived the study and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
4105880	25147754	PB	2	contributed in conceiving the study and revised the manuscript	contributed in conceiving the study and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
4105880	25147754	VWS	2	participated in the design of the study, performed the experiments and wrote the manuscript	participated in the design of the study, performed the experiments and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
4105880	25147754	YL	2	performed the experiments and commented on the manuscript	performed the experiments and commented on the manuscript	Performed the experiments	Investigation	YES
5553593	28797234	CS	2	drafted the manuscript|conceived of the study, and participated in its design	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5553593	28797234	CS	2	drafted the manuscript|conceived of the study, and participated in its design	conceived of the study, and participated in its design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5553593	28797234	HG	2	carried out the molecular studies|performed the statistical analysis	carried out the molecular studies	Performed the experiments	Investigation	YES
5553593	28797234	HG	2	carried out the molecular studies|performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
5553593	28797234	HW	2	conceived of the study, and participated in its design	conceived of the study, and participated in its design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5553593	28797234	JH	2	carried out the molecular studies	carried out the molecular studies	Performed the experiments	Investigation	YES
5553593	28797234	KJ	2	carried out the molecular studies	carried out the molecular studies	Performed the experiments	Investigation	YES
5553593	28797234	MJ	2	took care the plants	took care the plants	Performed the experiments	Investigation	YES
5553593	28797234	SF	2	carried out the molecular studies|acquired of funding and helped to draft the manuscript	carried out the molecular studies	Performed the experiments	Investigation	YES
5553593	28797234	SF	2	carried out the molecular studies|acquired of funding and helped to draft the manuscript	acquired of funding and helped to draft the manuscript	Wrote the paper	Funding acquisition|Writing - Original Draft	YES
5321646	28229437	AMMdS	2	added important points to the discussion	added important points to the discussion	-	-	NO
5321646	28229437	AP	2	were responsible for the experimental design and data collection	were responsible for the experimental design and data collection	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5321646	28229437	AW	2	greatly contributed to the methodology and discussion of the findings	greatly contributed to the methodology and discussion of the findings	Performed the experiments	Methodology	YES
5321646	28229437	DVG	2	was involved in the data analysis and strongly contributed to the discussion of the results	was involved in the data analysis and strongly contributed to the discussion of the results	Analyzed the data	Formal analysis	YES
5321646	28229437	ILA	2	jointly developed the concept and design of the manuscript|wrote the first draft, and all previously mentioned co-authors critically reviewed and edited the original and every subsequent draft	jointly developed the concept and design of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5321646	28229437	ILA	2	jointly developed the concept and design of the manuscript|wrote the first draft, and all previously mentioned co-authors critically reviewed and edited the original and every subsequent draft	wrote the first draft, and all previously mentioned co-authors critically reviewed and edited the original and every subsequent draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5321646	28229437	JD	2	were responsible for the experimental design and data collection	were responsible for the experimental design and data collection	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5321646	28229437	MK	2	greatly contributed to the methodology and discussion of the findings	greatly contributed to the methodology and discussion of the findings	Performed the experiments	Methodology	YES
5321646	28229437	RB	2	jointly developed the concept and design of the manuscript	jointly developed the concept and design of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5321646	28229437	RD	2	added important points to the discussion	added important points to the discussion	-	-	NO
2874510	20459662	DE	2	conceived of the study, participated in its design and coordination and helped to draft the manuscript	conceived of the study, participated in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
2874510	20459662	EP	2	carried out the analysis and interpretation of the data, and drafted the manuscript	carried out the analysis and interpretation of the data, and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
2874510	20459662	JC	2	conceived of the study, participated in its design and coordination and helped to draft the manuscript	conceived of the study, participated in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
2874510	20459662	KK	2	conceived of the study, participated in its design and coordination and helped to draft the manuscript	conceived of the study, participated in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
4124662	24103325	EF	PLoS52	conceived and designed the study|analyzed the data	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4124662	24103325	EF	PLoS52	conceived and designed the study|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
4124662	24103325	HM	PLoS52	conceived and designed the study|conceived and designed the study|analyzed the data|drafted the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4124662	24103325	HM	PLoS52	conceived and designed the study|conceived and designed the study|analyzed the data|drafted the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4124662	24103325	HM	PLoS52	conceived and designed the study|conceived and designed the study|analyzed the data|drafted the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
4124662	24103325	HM	PLoS52	conceived and designed the study|conceived and designed the study|analyzed the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4124662	24103325	HS	PLoS52	analyzed the data|drafted the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
4124662	24103325	HS	PLoS52	analyzed the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4124662	24103325	KK	PLoS52	conceived and designed the study|drafted the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4124662	24103325	KK	PLoS52	conceived and designed the study|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4124662	24103325	MS	PLoS52	conceived and designed the study|analyzed the data|drafted the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4124662	24103325	MS	PLoS52	conceived and designed the study|analyzed the data|drafted the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
4124662	24103325	MS	PLoS52	conceived and designed the study|analyzed the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4124662	24103325	MU	PLoS52	conceived and designed the study|drafted the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4124662	24103325	MU	PLoS52	conceived and designed the study|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4124662	24103325	YT	PLoS52	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
1855004	17476323	DG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Built and tested the model	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1855004	17476323	DG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Built and tested the model	Performed the experiments	Performed the experiments	Investigation	YES
1855004	17476323	DG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Built and tested the model	Analyzed the data	Analyzed the data	Formal analysis	YES
1855004	17476323	DG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Built and tested the model	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1855004	17476323	DG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Built and tested the model	Built and tested the model	Performed the experiments	Investigation|Methodology	YES
1855004	17476323	DW	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1855004	17476323	DW	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1855004	17476323	FY	PLoS5	Performed the experiments|Built and tested the model	Performed the experiments	Performed the experiments	Investigation	YES
1855004	17476323	FY	PLoS5	Performed the experiments|Built and tested the model	Built and tested the model	Performed the experiments	Investigation|Methodology	YES
1855004	17476323	GB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1855004	17476323	GB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1855004	17476323	GB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1855004	17476323	JE	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1855004	17476323	JE	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1855004	17476323	JE	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1855004	17476323	RM	PLoS5	Performed the experiments|Built and tested the model	Performed the experiments	Performed the experiments	Investigation	YES
1855004	17476323	RM	PLoS5	Performed the experiments|Built and tested the model	Built and tested the model	Performed the experiments	Investigation|Methodology	YES
4412529	25919665	IWP	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412529	25919665	IWP	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4412529	25919665	IWP	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412529	25919665	JJH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412529	25919665	JJH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412529	25919665	JJH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412529	25919665	JJH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412529	25919665	XL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412529	25919665	XL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412529	25919665	XL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412529	25919665	XL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412529	25919665	XL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412529	25919665	YF	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412529	25919665	YF	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4412529	25919665	YF	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5402351	28480027	GHZ	2	made a contribution to interpretation of data	made a contribution to interpretation of data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5402351	28480027	JA	2	designed the study and supervised the experiment performance and data analyzing during the whole process as the corresponding authors	designed the study and supervised the experiment performance and data analyzing during the whole process as the corresponding authors	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation|Methodology|Supervision	YES
5402351	28480027	LZ	2	contributed equally to conducting the study, drafting the manuscript and participating in data acquisition	contributed equally to conducting the study, drafting the manuscript and participating in data acquisition	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Resources|Writing - Original Draft	YES
5402351	28480027	PL	2	made a contribution to interpretation of data	made a contribution to interpretation of data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5402351	28480027	TC	2	contributed equally to conducting the study, drafting the manuscript and participating in data acquisition	contributed equally to conducting the study, drafting the manuscript and participating in data acquisition	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Resources|Writing - Original Draft	YES
5402351	28480027	WMY	2	contributed equally to conducting the study, drafting the manuscript and participating in data acquisition	contributed equally to conducting the study, drafting the manuscript and participating in data acquisition	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Resources|Writing - Original Draft	YES
5402351	28480027	ZMZ	2	designed the study and supervised the experiment performance and data analyzing during the whole process as the corresponding authors	designed the study and supervised the experiment performance and data analyzing during the whole process as the corresponding authors	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation|Methodology|Supervision	YES
5323339	28233160	AS	2	was in charge of the patient selection, manual delineation of tumours in morphological images, and manuscript revision	was in charge of the patient selection, manual delineation of tumours in morphological images, and manuscript revision	Performed the experiments|Analyzed the data|Wrote the paper	Investigation|Visualization|Writing - Review & Editing	YES
5323339	28233160	JG	2	contributed to the original idea, planning of the study, computer programming of segmentation and evaluation routines, monte carlo simulations, evaluation of data, and manuscript preparation	contributed to the original idea, planning of the study, computer programming of segmentation and evaluation routines, monte carlo simulations, evaluation of data, and manuscript preparation	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Methodology|Resources|Software|Writing - Original Draft	YES
5323339	28233160	KSG	2	also contributed to the original idea, initiation and planning of the study, supervision in method development, and manuscript revision	also contributed to the original idea, initiation and planning of the study, supervision in method development, and manuscript revision	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Methodology|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
5553655	28800729	C-KK	2	designed the research and wrote the paper	designed the research and wrote the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5553655	28800729	CPH	2	designed the research and wrote the paper|performed the research	designed the research and wrote the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5553655	28800729	CPH	2	designed the research and wrote the paper|performed the research	performed the research	Performed the experiments	Investigation	YES
5553655	28800729	JL	2	designed the research and wrote the paper	designed the research and wrote the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5553655	28800729	JP	2	performed the research	performed the research	Performed the experiments	Investigation	YES
5553655	28800729	ML	2	performed the research	performed the research	Performed the experiments	Investigation	YES
5553655	28800729	SGP	2	performed the research	performed the research	Performed the experiments	Investigation	YES
5553655	28800729	YL	2	performed the research	performed the research	Performed the experiments	Investigation	YES
5553655	28800729	YU	2	performed the research	performed the research	Performed the experiments	Investigation	YES
2876074	20459623	BKS	2	was responsible for the study design and assistance with manuscript preparation	was responsible for the study design and assistance with manuscript preparation	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
2876074	20459623	CGM	2	were responsible for data collection/entry and assistance with manuscript preparation	were responsible for data collection/entry and assistance with manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Investigation|Writing - Original Draft	YES
2876074	20459623	JFT	2	were responsible for data collection/entry and assistance with manuscript preparation	were responsible for data collection/entry and assistance with manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Investigation|Writing - Original Draft	YES
2876074	20459623	REC	2	were responsible for data collection/entry and assistance with manuscript preparation	were responsible for data collection/entry and assistance with manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Investigation|Writing - Original Draft	YES
2876074	20459623	RJB	2	was responsible for the study design, overseeing data collection, performance of biochemical assays, statistical analysis, and preparation of the manuscript	was responsible for the study design, overseeing data collection, performance of biochemical assays, statistical analysis, and preparation of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Supervision|Writing - Original Draft	YES
2876074	20459623	TMF	2	were responsible for data collection/entry and assistance with manuscript preparation	were responsible for data collection/entry and assistance with manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Investigation|Writing - Original Draft	YES
5693882	29181013	AP	PLoS52	drafted the figures, tables, and manuscript|conceived and designed the experiments	drafted the figures, tables, and manuscript	Wrote the paper	Visualization|Writing - Original Draft	YES
5693882	29181013	AP	PLoS52	drafted the figures, tables, and manuscript|conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5693882	29181013	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5693882	29181013	KN	PLoS52	did transcript abundance analysis	did transcript abundance analysis	-	-	NO
5693882	29181013	PG	PLoS52	carried out in silico analysis|did transcript abundance analysis|drafted the figures, tables, and manuscript	carried out in silico analysis	Performed the experiments	Formal analysis|Investigation	YES
5693882	29181013	PG	PLoS52	carried out in silico analysis|did transcript abundance analysis|drafted the figures, tables, and manuscript	did transcript abundance analysis	-	-	NO
5693882	29181013	PG	PLoS52	carried out in silico analysis|did transcript abundance analysis|drafted the figures, tables, and manuscript	drafted the figures, tables, and manuscript	Wrote the paper	Visualization|Writing - Original Draft	YES
5693882	29181013	SS-P	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4131155	25136511	FO	2	conceived of the study, participated in its design and coordination, interpreted the data and helped to draft the manuscript	conceived of the study, participated in its design and coordination, interpreted the data and helped to draft the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Project administration|Writing - Original Draft	YES
4131155	25136511	KO	2	participated in its design and coordination, performed the experiments, interpreted the dates and helped to draft the manuscript	participated in its design and coordination, performed the experiments, interpreted the dates and helped to draft the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Project administration|Writing - Original Draft	YES
4131155	25136511	MK	2	conceived of the study, participated in its design and coordination, interpreted the data and drafted the manuscript	conceived of the study, participated in its design and coordination, interpreted the data and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Project administration|Writing - Original Draft	YES
4131155	25136511	MS	2	conceived of the study, participated in its design and coordination, performed the experiments, interpreted the data and drafted the manuscript	conceived of the study, participated in its design and coordination, performed the experiments, interpreted the data and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Project administration|Writing - Original Draft	YES
4131155	25136511	NO	2	performed the experiments and the data analysis	performed the experiments and the data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4131155	25136511	SM	2	performed the experiments and the data analysis	performed the experiments and the data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4131155	25136511	YS	2	conceived of the study, participated in its design and coordination, and interpreted the data	conceived of the study, participated in its design and coordination, and interpreted the data	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology|Project administration	YES
5510290	28744362	FQL	2	designed this study	designed this study	Conceived and designed the experiments	Methodology	YES
5510290	28744362	KL	2	designed this study	designed this study	Conceived and designed the experiments	Methodology	YES
5510290	28744362	LLH	2	conducted statistical analysis	conducted statistical analysis	Analyzed the data	Formal analysis	YES
5510290	28744362	MC	2	conducted detections	conducted detections	Performed the experiments	Investigation	YES
5510290	28744362	MJW	2	established the animal model|conducted detections	established the animal model	Performed the experiments	Methodology	YES
5510290	28744362	MJW	2	established the animal model|conducted detections	conducted detections	Performed the experiments	Investigation	YES
5510290	28744362	MLT	2	conducted statistical analysis	conducted statistical analysis	Analyzed the data	Formal analysis	YES
5510290	28744362	SS	2	conducted detections	conducted detections	Performed the experiments	Investigation	YES
1855076	17476335	SC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Collected samples and sperm morphometric data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1855076	17476335	SC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Collected samples and sperm morphometric data	Analyzed the data	Analyzed the data	Formal analysis	YES
1855076	17476335	SC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Collected samples and sperm morphometric data	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1855076	17476335	SC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Collected samples and sperm morphometric data	Collected samples and sperm morphometric data	Performed the experiments	Investigation	YES
1855076	17476335	TB	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1855076	17476335	TB	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2876998	20441594	AHLJr	2	have conceived the idea of the manuscript and established the manuscripts general structure	have conceived the idea of the manuscript and established the manuscripts general structure	Conceived and designed the experiments	Conceptualization	YES
2876998	20441594	EF	2	have conceived the idea of the manuscript and established the manuscripts general structure	have conceived the idea of the manuscript and established the manuscripts general structure	Conceived and designed the experiments	Conceptualization	YES
2876998	20441594	GGA	2	have conceived the idea of the manuscript and established the manuscripts general structure|has written the first draft and the other authors have equally contributed to the final version, which was approved by all authors	have conceived the idea of the manuscript and established the manuscripts general structure	Conceived and designed the experiments	Conceptualization	YES
2876998	20441594	GGA	2	have conceived the idea of the manuscript and established the manuscripts general structure|has written the first draft and the other authors have equally contributed to the final version, which was approved by all authors	has written the first draft and the other authors have equally contributed to the final version, which was approved by all authors	Wrote the paper	Writing - Original Draft	YES
2876998	20441594	HN	2	have conceived the idea of the manuscript and established the manuscripts general structure	have conceived the idea of the manuscript and established the manuscripts general structure	Conceived and designed the experiments	Conceptualization	YES
2876998	20441594	MYS	2	have conceived the idea of the manuscript and established the manuscripts general structure	have conceived the idea of the manuscript and established the manuscripts general structure	Conceived and designed the experiments	Conceptualization	YES
2876998	20441594	SS	2	have conceived the idea of the manuscript and established the manuscripts general structure	have conceived the idea of the manuscript and established the manuscripts general structure	Conceived and designed the experiments	Conceptualization	YES
5763115	29445399	Alexandra Herzog	2	performed additional experiments and analyzed data	performed additional experiments and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5763115	29445399	Angelika A. Noegel	2	conceived the study, reviewed all data, and prepared the final versions of the manuscript, text, and figures	conceived the study, reviewed all data, and prepared the final versions of the manuscript, text, and figures	Conceived and designed the experiments|Wrote the paper	Conceptualization|Visualization|Writing - Original Draft|Writing - Review & Editing	YES
5763115	29445399	C. P. Unnikannan	2	performed additional experiments and analyzed data	performed additional experiments and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5763115	29445399	Carmen Mross	2	designed and carried out experiments, analyzed the data, prepared the figures, and wrote the manuscript|have equal contribution to this work	designed and carried out experiments, analyzed the data, prepared the figures, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Visualization|Writing - Original Draft	YES
5763115	29445399	Carmen Mross	2	designed and carried out experiments, analyzed the data, prepared the figures, and wrote the manuscript|have equal contribution to this work	have equal contribution to this work	-	-	NO
5763115	29445399	Clara Mohr	2	performed additional experiments and analyzed data	performed additional experiments and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5763115	29445399	Linlin Hao	2	performed additional experiments and analyzed data	performed additional experiments and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5763115	29445399	Ludwig Eichinger	2	conceived the study, reviewed all data, and prepared the final versions of the manuscript, text, and figures	conceived the study, reviewed all data, and prepared the final versions of the manuscript, text, and figures	Conceived and designed the experiments|Wrote the paper	Conceptualization|Visualization|Writing - Original Draft|Writing - Review & Editing	YES
5763115	29445399	Martina Munck	2	performed additional experiments and analyzed data	performed additional experiments and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5763115	29445399	Pranav Kelkar	2	performed additional experiments and analyzed data	performed additional experiments and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5763115	29445399	Sascha Neumann	2	conceived the study, reviewed all data, and prepared the final versions of the manuscript, text, and figures	conceived the study, reviewed all data, and prepared the final versions of the manuscript, text, and figures	Conceived and designed the experiments|Wrote the paper	Conceptualization|Visualization|Writing - Original Draft|Writing - Review & Editing	YES
5763115	29445399	Xin Xing	2	designed and carried out experiments, analyzed the data, prepared the figures, and wrote the manuscript|have equal contribution to this work	designed and carried out experiments, analyzed the data, prepared the figures, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Visualization|Writing - Original Draft	YES
5763115	29445399	Xin Xing	2	designed and carried out experiments, analyzed the data, prepared the figures, and wrote the manuscript|have equal contribution to this work	have equal contribution to this work	-	-	NO
5510291	28744363	AM	2	modified the language	modified the language	-	-	NO
5510291	28744363	BLZ	2	write the paper	write the paper	Wrote the paper	Writing - Original Draft	YES
5510291	28744363	FL	2	gave suggestions	gave suggestions	-	-	NO
5510291	28744363	JLH	2	write the paper	write the paper	Wrote the paper	Writing - Original Draft	YES
5510291	28744363	QH	2	modified the language	modified the language	-	-	NO
5510291	28744363	XJS	2	gave suggestions	gave suggestions	-	-	NO
4412530	25919389	AR	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4412530	25919389	GC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412530	25919389	GC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412530	25919389	GC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412530	25919389	JG	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412530	25919389	JG	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412530	25919389	LC	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4412530	25919389	OA	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4412530	25919389	OR	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412530	25919389	OR	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412530	25919389	OR	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4131161	25136510	All	2	authors have given final approval of the version to be published	authors have given final approval of the version to be published	-	-	NO
4131161	25136510	VHPE	2	authors have given final approval of the version to be published	authors have given final approval of the version to be published	-	-	NO
5328895	28244021	CN	2	contributed to the study design, drafting of the manuscript, and critical revision of the manuscript	contributed to the study design, drafting of the manuscript, and critical revision of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5328895	28244021	KM	2	contributed to the study design, drafting of the manuscript, and critical revision of the manuscript	contributed to the study design, drafting of the manuscript, and critical revision of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5328895	28244021	KT	2	contributed to the study design, preparation of the study, conducting of the measurements, analyzing of the data, drafting of the manuscript, and critical revision of the manuscript	contributed to the study design, preparation of the study, conducting of the measurements, analyzing of the data, drafting of the manuscript, and critical revision of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5328895	28244021	MJ	2	contributed to the study design, drafting of the manuscript, and critical revision of the manuscript	contributed to the study design, drafting of the manuscript, and critical revision of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5328895	28244021	TN	2	contributed to the study design, preparation of the study, conducting of the measurements, analyzing of the data, drafting of the manuscript, and critical revision of the manuscript	contributed to the study design, preparation of the study, conducting of the measurements, analyzing of the data, drafting of the manuscript, and critical revision of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5328895	28244021	YI	2	contributed to the preparation of the study, conducting of the measurements, and analyzing of the data	contributed to the preparation of the study, conducting of the measurements, and analyzing of the data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5328895	28244021	YM	2	contributed to the study design, preparation of the study, conducting of the measurements, analyzing of the data, drafting of the manuscript, and critical revision of the manuscript	contributed to the study design, preparation of the study, conducting of the measurements, analyzing of the data, drafting of the manuscript, and critical revision of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
2876999	20470411	All authors	2	contributed to the study design and reviewed and contributed to the final manuscript	contributed to the study design and reviewed and contributed to the final manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
2876999	20470411	EG	2	were responsible for data collection, statistical analysis, and manuscript preparation	were responsible for data collection, statistical analysis, and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
2876999	20470411	PJ	2	were responsible for data collection, statistical analysis, and manuscript preparation	were responsible for data collection, statistical analysis, and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
1855077	17476338	CS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1855077	17476338	DP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1855077	17476338	DP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1855077	17476338	DP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1855077	17476338	JS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1855077	17476338	RP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1855077	17476338	SC	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1855077	17476338	SC	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1855077	17476338	SH	PLoS5	Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1855077	17476338	SH	PLoS5	Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1855077	17476338	SH	PLoS5	Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1855077	17476338	SH	PLoS5	Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1855077	17476338	SH	PLoS5	Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1855077	17476338	SH	PLoS5	Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5693887	29181016	DW	2	conceived the article, planned its structure, discussed the literature, and wrote the article with	conceived the article, planned its structure, discussed the literature, and wrote the article with	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5693887	29181016	EP	2	assisted with the and wrote the article with	assisted with the and wrote the article with	Wrote the paper	Writing - Original Draft	YES
5693887	29181016	RP	2	assisted with the and wrote the article with	assisted with the and wrote the article with	Wrote the paper	Writing - Original Draft	YES
5553663	28800727	AA	2	provided critical reagents	provided critical reagents	Contributed reagents/materials/analysis tools	Resources	YES
5553663	28800727	AKA	2	provided critical reagents	provided critical reagents	Contributed reagents/materials/analysis tools	Resources	YES
5553663	28800727	DHKC	2	performed rflp haplotype analysis	performed rflp haplotype analysis	Performed the experiments	Investigation	YES
5553663	28800727	EMS	2	wrote the paper and conceived of the research	wrote the paper and conceived of the research	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5553663	28800727	GJM	2	provided critical reagents	provided critical reagents	Contributed reagents/materials/analysis tools	Resources	YES
5553663	28800727	GM	2	provided critical reagents	provided critical reagents	Contributed reagents/materials/analysis tools	Resources	YES
5553663	28800727	HQ	2	provided critical reagents	provided critical reagents	Contributed reagents/materials/analysis tools	Resources	YES
5553663	28800727	JJF	2	supervised the research and edited the paper	supervised the research and edited the paper	Wrote the paper	Supervision|Writing - Review & Editing	YES
5553663	28800727	LAF	2	edited the paper	edited the paper	Wrote the paper	Writing - Review & Editing	YES
5553663	28800727	MHS	2	supervised the research and edited the paper	supervised the research and edited the paper	Wrote the paper	Supervision|Writing - Review & Editing	YES
5553663	28800727	MSF	2	provided critical reagents	provided critical reagents	Contributed reagents/materials/analysis tools	Resources	YES
5553663	28800727	PS	2	supervised the research and edited the paper	supervised the research and edited the paper	Wrote the paper	Supervision|Writing - Review & Editing	YES
5510292	28744364	GC	2	were responsible for its drafting and revision	were responsible for its drafting and revision	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5510292	28744364	JYZ	2	were responsible for writing the manuscript	were responsible for writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5510292	28744364	RG	2	were responsible for its drafting and revision	were responsible for its drafting and revision	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5510292	28744364	YK	2	were responsible for its revision	were responsible for its revision	Wrote the paper	Writing - Review & Editing	YES
5510292	28744364	YPD	2	were responsible for writing the manuscript	were responsible for writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5510292	28744364	ZW	2	were responsible for its revision	were responsible for its revision	Wrote the paper	Writing - Review & Editing	YES
4143577	25177540	JS	2	designed the study|designed and performed the experimental work	designed the study	Conceived and designed the experiments	Methodology	YES
4143577	25177540	JS	2	designed the study|designed and performed the experimental work	designed and performed the experimental work	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4143577	25177540	LG	2	designed the study|participated herein	designed the study	Conceived and designed the experiments	Methodology	YES
4143577	25177540	LG	2	designed the study|participated herein	participated herein	-	-	NO
4143577	25177540	MS	2	designed and performed the experimental work	designed and performed the experimental work	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4143577	25177540	PS	2	contributed to the design and execution of the phylogenetic analysis|participated herein	contributed to the design and execution of the phylogenetic analysis	Conceived and designed the experiments|Performed the experiments	Investigation	YES
4143577	25177540	PS	2	contributed to the design and execution of the phylogenetic analysis|participated herein	participated herein	-	-	NO
1855078	17479162	GM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1855078	17479162	GM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1855078	17479162	GM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1855078	17479162	JW	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1855078	17479162	JW	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1855078	17479162	MO	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1855078	17479162	MO	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1855078	17479162	MO	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1855078	17479162	YA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1855078	17479162	YA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1855078	17479162	YA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5510293	28744365	HL	2	conceived the hypothesis and wrote a part of the paper	conceived the hypothesis and wrote a part of the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5510293	28744365	OYC	2	conceived the hypothesis, reviewed and edited the paper	conceived the hypothesis, reviewed and edited the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5510293	28744365	SRW	2	searched the references and modified the paper	searched the references and modified the paper	Wrote the paper	Writing - Review & Editing	YES
5510293	28744365	YJW	2	searched the references and wrote a part of the paper	searched the references and wrote a part of the paper	Wrote the paper	Writing - Original Draft	YES
2887392	20482784	CJW	2	acting as a thesis advisor, assisted with study design, data analysis and interpretation, and editing of the manuscript	acting as a thesis advisor, assisted with study design, data analysis and interpretation, and editing of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
2887392	20482784	CWM	2	participated in data collection, analysis and interpretation, and editing of the manuscript	participated in data collection, analysis and interpretation, and editing of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
2887392	20482784	MJS	2	acting as senior thesis advisor, participated in study design, screening and recruitment, data collection, analysis and interpretation, and final draft of the manuscript	acting as senior thesis advisor, participated in study design, screening and recruitment, data collection, analysis and interpretation, and final draft of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
2887392	20482784	MKT	2	acting as a thesis advisor, assisted with study design, data analysis and interpretation, and editing of the manuscript	acting as a thesis advisor, assisted with study design, data analysis and interpretation, and editing of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
2887392	20482784	RWM	2	participated in data collection and interpretation, and editing of the manuscript	participated in data collection and interpretation, and editing of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
2887392	20482784	SFG	2	participated as the lead author and participated in study design, screening and recruitment, data collection, analysis and interpretation, and final draft of the manuscript	participated as the lead author and participated in study design, screening and recruitment, data collection, analysis and interpretation, and final draft of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5328898	28244022	FK	2	contributed to the data analysis and interpretation	contributed to the data analysis and interpretation	Analyzed the data	Formal analysis	YES
5328898	28244022	HS	2	contributed to the design of the study	contributed to the design of the study	Conceived and designed the experiments	Methodology	YES
5328898	28244022	KH	2	contributed to the data analysis and interpretation|drafted the article	contributed to the data analysis and interpretation	Analyzed the data	Formal analysis	YES
5328898	28244022	KH	2	contributed to the data analysis and interpretation|drafted the article	drafted the article	Wrote the paper	Writing - Original Draft	YES
5328898	28244022	KK	2	contributed to the design of the study|drafted the article	contributed to the design of the study	Conceived and designed the experiments	Methodology	YES
5328898	28244022	KK	2	contributed to the design of the study|drafted the article	drafted the article	Wrote the paper	Writing - Original Draft	YES
5328898	28244022	NM	2	contributed to the data analysis and interpretation	contributed to the data analysis and interpretation	Analyzed the data	Formal analysis	YES
5328898	28244022	NOM	2	contributed to the design of the study|carried out the data analysis and interpretation|drafted the article	contributed to the design of the study	Conceived and designed the experiments	Methodology	YES
5328898	28244022	NOM	2	contributed to the design of the study|carried out the data analysis and interpretation|drafted the article	carried out the data analysis and interpretation	Analyzed the data	Formal analysis	YES
5328898	28244022	NOM	2	contributed to the design of the study|carried out the data analysis and interpretation|drafted the article	drafted the article	Wrote the paper	Writing - Original Draft	YES
5328898	28244022	NT	2	contributed to the design of the study|drafted the article	contributed to the design of the study	Conceived and designed the experiments	Methodology	YES
5328898	28244022	NT	2	contributed to the design of the study|drafted the article	drafted the article	Wrote the paper	Writing - Original Draft	YES
5328898	28244022	OM	2	contributed to the data analysis and interpretation|drafted the article	contributed to the data analysis and interpretation	Analyzed the data	Formal analysis	YES
5328898	28244022	OM	2	contributed to the data analysis and interpretation|drafted the article	drafted the article	Wrote the paper	Writing - Original Draft	YES
5328898	28244022	SY	2	contributed to the design of the study|carried out the data analysis and interpretation|drafted the article	contributed to the design of the study	Conceived and designed the experiments	Methodology	YES
5328898	28244022	SY	2	contributed to the design of the study|carried out the data analysis and interpretation|drafted the article	carried out the data analysis and interpretation	Analyzed the data	Formal analysis	YES
5328898	28244022	SY	2	contributed to the design of the study|carried out the data analysis and interpretation|drafted the article	drafted the article	Wrote the paper	Writing - Original Draft	YES
5328898	28244022	YM	2	performed pathological verification of igg4-rd	performed pathological verification of igg4-rd	Performed the experiments	Investigation|Validation	YES
4584049	26448928	Adebowale Adeniran	PLoS52	performed the pathology review of specimens	performed the pathology review of specimens	Performed the experiments	Investigation	YES
4584049	26448928	Brian Shuch	PLoS52	designed and oversaw the research study|analyzed and interpreted the data|wrote the paper	designed and oversaw the research study	Conceived and designed the experiments	Methodology|Supervision	YES
4584049	26448928	Brian Shuch	PLoS52	designed and oversaw the research study|analyzed and interpreted the data|wrote the paper	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
4584049	26448928	Brian Shuch	PLoS52	designed and oversaw the research study|analyzed and interpreted the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4584049	26448928	Fabio Parisi	PLoS52	analyzed and interpreted the data	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
4584049	26448928	Harriet M. Kluger	PLoS52	designed and oversaw the research study	designed and oversaw the research study	Conceived and designed the experiments	Methodology|Supervision	YES
4584049	26448928	Lucia B. Jilaveanu	PLoS52	designed and oversaw the research study|analyzed and interpreted the data|wrote the paper	designed and oversaw the research study	Conceived and designed the experiments	Methodology|Supervision	YES
4584049	26448928	Lucia B. Jilaveanu	PLoS52	designed and oversaw the research study|analyzed and interpreted the data|wrote the paper	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
4584049	26448928	Lucia B. Jilaveanu	PLoS52	designed and oversaw the research study|analyzed and interpreted the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4584049	26448928	Ryan Falbo	PLoS52	performed the immunofluorescent staining and data assembly	performed the immunofluorescent staining and data assembly	Performed the experiments	Investigation	YES
4584049	26448928	Yuval Kluger	PLoS52	analyzed and interpreted the data	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
4412532	25919592	AKR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412532	25919592	AKR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412532	25919592	AKR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412532	25919592	AKR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412532	25919592	AKR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412532	25919592	CH	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412532	25919592	CH	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412532	25919592	CH	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412532	25919592	GTG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412532	25919592	GTG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412532	25919592	GTG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412532	25919592	GTG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412532	25919592	GTG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412532	25919592	S. Baur	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412532	25919592	S. Baur	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412532	25919592	S. Baur	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412532	25919592	S. Beache	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412532	25919592	S. Beache	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412532	25919592	S. Beache	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412532	25919592	SKK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412532	25919592	SKK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412532	25919592	SKK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412532	25919592	SKK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412532	25919592	SKK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412532	25919592	TRR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412532	25919592	TRR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412532	25919592	TRR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412532	25919592	TRR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412532	25919592	TRR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4192553	25309846	FS	2	initiated the project	initiated the project	Conceived and designed the experiments	Conceptualization	YES
4192553	25309846	H. All	2	authors analyzed the data, wrote and approved the final manuscript	authors analyzed the data, wrote and approved the final manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
4192553	25309846	UB	2	initiated the project	initiated the project	Conceived and designed the experiments	Conceptualization	YES
5553679	28800724	The authors	2	contributed equally to the work and read and approved the final manuscript	contributed equally to the work and read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5693889	29181017	KR	2	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5693889	29181017	LL	2	in radioisotope labeling and fluorescent tracing|approved the final version of the manuscript	in radioisotope labeling and fluorescent tracing	Performed the experiments	Investigation	YES
5693889	29181017	LL	2	in radioisotope labeling and fluorescent tracing|approved the final version of the manuscript	approved the final version of the manuscript	-	-	NO
5693889	29181017	RG	2	designed the experiments|approved the final version of the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5693889	29181017	RG	2	designed the experiments|approved the final version of the manuscript	approved the final version of the manuscript	-	-	NO
5693889	29181017	all authors	2	approved the final version of the manuscript	approved the final version of the manuscript	-	-	NO
5510294	28744366	DXF	2	were responsible for its revision	were responsible for its revision	Wrote the paper	Writing - Review & Editing	YES
5510294	28744366	GC	2	were responsible for its revision	were responsible for its revision	Wrote the paper	Writing - Review & Editing	YES
5510294	28744366	JYZ	2	were responsible for writing the manuscript	were responsible for writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5510294	28744366	YK	2	were responsible for its drafting and revision	were responsible for its drafting and revision	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5510294	28744366	YPD	2	were responsible for writing the manuscript	were responsible for writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5510294	28744366	ZX	2	were responsible for its drafting and revision	were responsible for its drafting and revision	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
1855079	17476339	KM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1855079	17476339	MS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1855079	17476339	PB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Discovered the original structures	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1855079	17476339	PB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Discovered the original structures	Performed the experiments	Performed the experiments	Investigation	YES
1855079	17476339	PB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Discovered the original structures	Analyzed the data	Analyzed the data	Formal analysis	YES
1855079	17476339	PB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Discovered the original structures	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1855079	17476339	PB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Discovered the original structures	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1855079	17476339	PB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Discovered the original structures	Discovered the original structures	-	-	NO
1855079	17476339	RP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1855079	17476339	RP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1855079	17476339	RP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1855079	17476339	RW	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1855079	17476339	TB	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1855079	17476339	TB	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2887393	20482881	JL	2	played an important role in data collection and manuscript preparation	played an important role in data collection and manuscript preparation	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
2887393	20482881	JU	2	played an important role in data collection and manuscript preparation	played an important role in data collection and manuscript preparation	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
2887393	20482881	MM	2	played an important role in data collection and manuscript preparation	played an important role in data collection and manuscript preparation	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
2887393	20482881	TJ	2	was the primary author of the manuscript and played an important role in the data collection and assessment	was the primary author of the manuscript and played an important role in the data collection and assessment	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4230170	25401068	GG-LOX	2	mrna analysis, the western blot experiments, the immunoprecipitation, the proteomics analysis, fermentation experiments, and drafted the manuscript	mrna analysis, the western blot experiments, the immunoprecipitation, the proteomics analysis, fermentation experiments, and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4230170	25401068	JATR	2	conceived and performed the proteomics sample preparation and contributed to the manuscript	conceived and performed the proteomics sample preparation and contributed to the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
4230170	25401068	JPvS	2	was responsible for the mutagenesis work and analysis presented in this paper	was responsible for the mutagenesis work and analysis presented in this paper	Performed the experiments	Investigation	YES
4230170	25401068	LHdG	2	designed the experiments participated to draft the manuscript	designed the experiments participated to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4230170	25401068	RH	2	designed the experiments participated to draft the manuscript	designed the experiments participated to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4412533	25919137	AA	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper|Decision to share specimens for testing	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412533	25919137	AA	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper|Decision to share specimens for testing	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412533	25919137	AA	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper|Decision to share specimens for testing	Decision to share specimens for testing	Performed the experiments	Investigation	YES
4412533	25919137	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412533	25919137	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412533	25919137	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412533	25919137	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412533	25919137	AM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Decision to share specimens for testing	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412533	25919137	AM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Decision to share specimens for testing	Analyzed the data	Analyzed the data	Formal analysis	YES
4412533	25919137	AM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Decision to share specimens for testing	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412533	25919137	AM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Decision to share specimens for testing	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412533	25919137	AM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Decision to share specimens for testing	Decision to share specimens for testing	Performed the experiments	Investigation	YES
4412533	25919137	DE	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412533	25919137	DE	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412533	25919137	DE	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412533	25919137	DE	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412533	25919137	ME	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412533	25919137	ME	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412533	25919137	ME	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412533	25919137	ME	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412533	25919137	ST	PLoS5	Analyzed the data|Analyzed the data|Wrote the paper|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412533	25919137	ST	PLoS5	Analyzed the data|Analyzed the data|Wrote the paper|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412533	25919137	ST	PLoS5	Analyzed the data|Analyzed the data|Wrote the paper|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412533	25919137	ST	PLoS5	Analyzed the data|Analyzed the data|Wrote the paper|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412533	25919137	VP	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412533	25919137	VP	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412533	25919137	VP	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412533	25919137	XL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412533	25919137	XL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412533	25919137	XL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412533	25919137	YT	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412533	25919137	YT	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412533	25919137	YT	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5510295	28744367	JHH	2	planned the manuscript|edited and finalized the manuscript|both contributed to revisions of the manuscript	planned the manuscript	Conceived and designed the experiments	Conceptualization	YES
5510295	28744367	JHH	2	planned the manuscript|edited and finalized the manuscript|both contributed to revisions of the manuscript	edited and finalized the manuscript	Wrote the paper	Writing - Review & Editing	YES
5510295	28744367	JHH	2	planned the manuscript|edited and finalized the manuscript|both contributed to revisions of the manuscript	both contributed to revisions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5510295	28744367	NPP	2	performed literature search and analysis|both contributed to revisions of the manuscript	performed literature search and analysis	Performed the experiments	Formal analysis|Investigation	YES
5510295	28744367	NPP	2	performed literature search and analysis|both contributed to revisions of the manuscript	both contributed to revisions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5339262	28266002	ALS	2	pathology were crucial for the design, analysis and interpretation of the results of this project|were also particularly involved in the revising of the manuscript	pathology were crucial for the design, analysis and interpretation of the results of this project	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5339262	28266002	ALS	2	pathology were crucial for the design, analysis and interpretation of the results of this project|were also particularly involved in the revising of the manuscript	were also particularly involved in the revising of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5339262	28266002	AM	2	participated in the acquisition of the cognitive data, especially in the careful screening of our cohort	participated in the acquisition of the cognitive data, especially in the careful screening of our cohort	Performed the experiments	Investigation	YES
5339262	28266002	AP	2	participated in the acquisition of the cognitive data, especially in the careful screening of our cohort	participated in the acquisition of the cognitive data, especially in the careful screening of our cohort	Performed the experiments	Investigation	YES
5339262	28266002	BD	2	supervised and coordinated the teamwork from start to finish	supervised and coordinated the teamwork from start to finish	-	Project administration|Supervision	YES
5339262	28266002	FD	2	greatly contributed to the neuroimaging part of this study|provided their critical revision of the manuscript	greatly contributed to the neuroimaging part of this study	Analyzed the data	Visualization	YES
5339262	28266002	FD	2	greatly contributed to the neuroimaging part of this study|provided their critical revision of the manuscript	provided their critical revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5339262	28266002	FE	2	provided their critical revision of the manuscript	provided their critical revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5339262	28266002	FV	2	supervised and coordinated the teamwork from start to finish	supervised and coordinated the teamwork from start to finish	-	Project administration|Supervision	YES
5339262	28266002	LC	2	provided their critical revision of the manuscript	provided their critical revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5339262	28266002	MSB	2	was actively involved in this study from design to drafting|conducted all the statistical analyses and played a central role in interpreting the results and writing the article	was actively involved in this study from design to drafting	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5339262	28266002	MSB	2	was actively involved in this study from design to drafting|conducted all the statistical analyses and played a central role in interpreting the results and writing the article	conducted all the statistical analyses and played a central role in interpreting the results and writing the article	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5553681	28800721	AK	2	contributed to the execution of experiments and interpretation of the data	contributed to the execution of experiments and interpretation of the data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5553681	28800721	All authors	2	read, edited and approved the final manuscript	read, edited and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5553681	28800721	IHB	2	contributed to the design of experiments, execution of experiments, data analysis, interpretation of the data and preparation of the manuscript	contributed to the design of experiments, execution of experiments, data analysis, interpretation of the data and preparation of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
5553681	28800721	RKP	2	contributed to the design of experiments, interpretation of the data and preparation of the manuscript	contributed to the design of experiments, interpretation of the data and preparation of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
5693890	29181015	All authors	2	agreed on the manuscript	agreed on the manuscript	-	-	NO
5693890	29181015	MY	2	conceived and designed the research|performed the experiments and analyzed data|wrote the manuscript	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5693890	29181015	MY	2	conceived and designed the research|performed the experiments and analyzed data|wrote the manuscript	performed the experiments and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5693890	29181015	MY	2	conceived and designed the research|performed the experiments and analyzed data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5693890	29181015	P-CW	2	participated in algal cultivations	participated in algal cultivations	-	-	NO
5693890	29181015	P-LS	2	provided technical assistance	provided technical assistance	Performed the experiments	Investigation	YES
5693890	29181015	SX	2	conceived and designed the research|wrote the manuscript|supervised specific experiments	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5693890	29181015	SX	2	conceived and designed the research|wrote the manuscript|supervised specific experiments	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5693890	29181015	SX	2	conceived and designed the research|wrote the manuscript|supervised specific experiments	supervised specific experiments	-	Supervision	YES
5693890	29181015	Y-DC	2	designed the photobioreactors and illumination systems	designed the photobioreactors and illumination systems	Conceived and designed the experiments	-	YES
5693890	29181015	YF	2	participated in algal cultivations	participated in algal cultivations	-	-	NO
5693890	29181015	Z-YC	2	supervised specific experiments	supervised specific experiments	-	Supervision	YES
5510296	28744368	EFF	2	reviewed, analyzed, chose the representative slices, formatted, and performed all of the calculations on the imaging, drafted, and revised the manuscript	reviewed, analyzed, chose the representative slices, formatted, and performed all of the calculations on the imaging, drafted, and revised the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Visualization|Writing - Original Draft|Writing - Review & Editing	YES
5510296	28744368	PGH	2	consulted on the patient during the patients hospitalization and after discharge from the hospital, evaluated the patient, performed the hyperbaric treatment, videoed the patient, drafted, and revised the manuscript	consulted on the patient during the patients hospitalization and after discharge from the hospital, evaluated the patient, performed the hyperbaric treatment, videoed the patient, drafted, and revised the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
4230719	24670060	CL	2	performed growth profiling experimentation|contributed to experimental design and manuscript writing	performed growth profiling experimentation	Performed the experiments	Investigation	YES
4230719	24670060	CL	2	performed growth profiling experimentation|contributed to experimental design and manuscript writing	contributed to experimental design and manuscript writing	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
4230719	24670060	GMR	2	contributed to experimental design, manuscript writing and environmental sampling	contributed to experimental design, manuscript writing and environmental sampling	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
4230719	24670060	GNS	2	performed environmental characterization and strain purification/identification	performed environmental characterization and strain purification/identification	Performed the experiments	Investigation	YES
4230719	24670060	JAS	2	contributed to experimental design and manuscript writing	contributed to experimental design and manuscript writing	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
4230719	24670060	JDC	2	performed growth and lipid screening experiments	performed growth and lipid screening experiments	Performed the experiments	Investigation	YES
4230719	24670060	JKE	2	contributed to sampling, experimentation, experimental design and manuscript preparation	contributed to sampling, experimentation, experimental design and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
4230719	24670060	JM	2	performed growth profiling experimentation	performed growth profiling experimentation	Performed the experiments	Investigation	YES
4230719	24670060	KZ	2	performed gas chromatography and gravimetric lipid analysis	performed gas chromatography and gravimetric lipid analysis	Performed the experiments	Investigation	YES
4230719	24670060	NSH	2	performed growth profiling experimentation	performed growth profiling experimentation	Performed the experiments	Investigation	YES
2891663	20500899	AY	2	performed data collection	performed data collection	Performed the experiments	Investigation	YES
2891663	20500899	DL	2	was responsible for obtaining funding, designing the study, establishing community connections, performing laboratory testing, and performing data analysis	was responsible for obtaining funding, designing the study, establishing community connections, performing laboratory testing, and performing data analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Funding acquisition|Investigation|Methodology	YES
2891663	20500899	J Bloomer	2	assisted with manuscript writing and preparation	assisted with manuscript writing and preparation	Wrote the paper	Writing - Original Draft	YES
2891663	20500899	PP	2	assisted with data collection and in establishing community connections	assisted with data collection and in establishing community connections	Performed the experiments	Investigation	YES
2891663	20500899	SP	2	assisted with data collection and in establishing community connections	assisted with data collection and in establishing community connections	Performed the experiments	Investigation	YES
2891663	20500899	TS	2	performed data collection	performed data collection	Performed the experiments	Investigation	YES
5340791	28271461	FP	PLoS52	performed the research|analysed the data|wrote the manuscript	performed the research	Performed the experiments	Investigation	YES
5340791	28271461	FP	PLoS52	performed the research|analysed the data|wrote the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
5340791	28271461	FP	PLoS52	performed the research|analysed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5340791	28271461	HS	PLoS52	contributed to the administrative, technical or material support of the study	contributed to the administrative, technical or material support of the study	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Project administration|Resources	YES
5340791	28271461	LN	PLoS52	performed the research	performed the research	Performed the experiments	Investigation	YES
5340791	28271461	MH	PLoS52	contributed to the administrative, technical or material support of the study	contributed to the administrative, technical or material support of the study	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Project administration|Resources	YES
5340791	28271461	MM	PLoS52	designed the research study|contributed to the administrative, technical or material support of the study|wrote the manuscript	designed the research study	Conceived and designed the experiments	Methodology	YES
5340791	28271461	MM	PLoS52	designed the research study|contributed to the administrative, technical or material support of the study|wrote the manuscript	contributed to the administrative, technical or material support of the study	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Project administration|Resources	YES
5340791	28271461	MM	PLoS52	designed the research study|contributed to the administrative, technical or material support of the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5340791	28271461	MZ	PLoS52	performed the research|designed the research study|analysed the data|wrote the manuscript	performed the research	Performed the experiments	Investigation	YES
5340791	28271461	MZ	PLoS52	performed the research|designed the research study|analysed the data|wrote the manuscript	designed the research study	Conceived and designed the experiments	Methodology	YES
5340791	28271461	MZ	PLoS52	performed the research|designed the research study|analysed the data|wrote the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
5340791	28271461	MZ	PLoS52	performed the research|designed the research study|analysed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5340791	28271461	WW	PLoS52	contributed to the administrative, technical or material support of the study|wrote the manuscript	contributed to the administrative, technical or material support of the study	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Project administration|Resources	YES
5340791	28271461	WW	PLoS52	contributed to the administrative, technical or material support of the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4412534	25919140	AB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412534	25919140	AB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412534	25919140	AB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412534	25919140	AR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412534	25919140	AR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412534	25919140	AR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412534	25919140	AR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412534	25919140	AW	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4412534	25919140	AW	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412534	25919140	HD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412534	25919140	HD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412534	25919140	HD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412534	25919140	HVDK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412534	25919140	HVDK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412534	25919140	HVDK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412534	25919140	LGH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412534	25919140	LGH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4412534	25919140	LGH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4412534	25919140	MD	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412534	25919140	MRD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412534	25919140	MRD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4412534	25919140	MRD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4412534	25919140	NH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412534	25919140	NH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4412534	25919140	NH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4412534	25919140	NK	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412534	25919140	NK	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4412534	25919140	WS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412534	25919140	WS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412534	25919140	WS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412534	25919140	WS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5694171	29181014	All authors	2	have read and approved the final manuscript	have read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5694171	29181014	LR	2	contributed samples and performed the experiments	contributed samples and performed the experiments	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5694171	29181014	MG	2	contributed samples and performed the experiments|analyzed the data and drafted the manuscript	contributed samples and performed the experiments	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5694171	29181014	MG	2	contributed samples and performed the experiments|analyzed the data and drafted the manuscript	analyzed the data and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5694171	29181014	XP	2	conceived the study and participated in its design|analyzed the data and drafted the manuscript	conceived the study and participated in its design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5694171	29181014	XP	2	conceived the study and participated in its design|analyzed the data and drafted the manuscript	analyzed the data and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5553732	28797221	HS	2	conducted the pcoa analysis, most of the gwas and calculated the genomic heritability	conducted the pcoa analysis, most of the gwas and calculated the genomic heritability	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5553732	28797221	JB	2	accomplished the analysis with the pyrad pipeline and contributed to the analysis of the genetic structure	accomplished the analysis with the pyrad pipeline and contributed to the analysis of the genetic structure	Performed the experiments	Investigation	YES
5553732	28797221	JCR	2	significantly contributed to the study design and quantitative analysis of the data	significantly contributed to the study design and quantitative analysis of the data	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Methodology|Resources	YES
5553732	28797221	JD	2	supervised and designed the gc-ms analysis and contributed to study design	supervised and designed the gc-ms analysis and contributed to study design	Conceived and designed the experiments	Methodology|Supervision	YES
5553732	28797221	LGO	2	conceived the project|performed the experiments, managed the main data analysis, including gwas analysis, and wrote the manuscript	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5553732	28797221	LGO	2	conceived the project|performed the experiments, managed the main data analysis, including gwas analysis, and wrote the manuscript	performed the experiments, managed the main data analysis, including gwas analysis, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Formal analysis|Investigation|Writing - Original Draft	YES
5553732	28797221	PM	2	performed the gc-ms and analysed the compounds	performed the gc-ms and analysed the compounds	Performed the experiments	Investigation	YES
5553732	28797221	SP	2	supervised and designed the gc-ms analysis and contributed to study design	supervised and designed the gc-ms analysis and contributed to study design	Conceived and designed the experiments	Methodology|Supervision	YES
5553732	28797221	TFS	2	conceived the project|was a major contributor in designing the study and in writing the manuscript	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5553732	28797221	TFS	2	conceived the project|was a major contributor in designing the study and in writing the manuscript	was a major contributor in designing the study and in writing the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4304379	25421877	Both authors	2	contributed equally	contributed equally	-	-	NO
5510297	28744359	NM	2	contributed for reagents and corrected the paper	contributed for reagents and corrected the paper	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Review & Editing	YES
5510297	28744359	QL	2	conceived the study, designed the algorithms, performed the experiment, analyzed the experiment results, and wrote the manuscript	conceived the study, designed the algorithms, performed the experiment, analyzed the experiment results, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Software|Writing - Original Draft	YES
5510297	28744359	YT	2	contributed for reagents, conducted the western blot experiment, and corrected the manuscript	contributed for reagents, conducted the western blot experiment, and corrected the manuscript	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Resources|Writing - Review & Editing	YES
4230809	25401064	AK	2	carried out the molecular genetic studies, participated in the sequence alignment, drafted the manuscript, in the design of the study and performed the statistical analysis	carried out the molecular genetic studies, participated in the sequence alignment, drafted the manuscript, in the design of the study and performed the statistical analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4230809	25401064	ZS	2	have made substantial contributions to conception and design, or acquisition of data, or analysis and interpretation of data	have made substantial contributions to conception and design, or acquisition of data, or analysis and interpretation of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
4584051	26448945	Denarda Dangaj	2	contributed equally to this work	contributed equally to this work	-	-	NO
4584051	26448945	Evripidis Lanitis	2	contributed equally to this work	contributed equally to this work	-	-	NO
2892463	20525371	CAT	2	participated in supervision and provided oversight in drafting the manuscript	participated in supervision and provided oversight in drafting the manuscript	Wrote the paper	Supervision|Writing - Original Draft	YES
2892463	20525371	MO	2	assisted in the study concept and manuscript preparation	assisted in the study concept and manuscript preparation	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
2892463	20525371	SK	2	contributed to protocol development, statistical analysis and interpretation of the data and drafting the manuscript	contributed to protocol development, statistical analysis and interpretation of the data and drafting the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Original Draft	YES
2892463	20525371	SM	2	assisted in recruitment of the participants, data collection, clinical supply management and drafting the manuscript	assisted in recruitment of the participants, data collection, clinical supply management and drafting the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
1855081	17487270	JC	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Wrote the paper|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1855081	17487270	JC	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Wrote the paper|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1855081	17487270	JC	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Wrote the paper|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1855081	17487270	JC	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Wrote the paper|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1855081	17487270	JC	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Wrote the paper|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1855081	17487270	JC	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Wrote the paper|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1855081	17487270	TK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1855081	17487270	TK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1855081	17487270	TK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1855081	17487270	TK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1855081	17487270	TK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412535	25918841	AB	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412535	25918841	AC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4412535	25918841	AC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412535	25918841	AGU	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412535	25918841	AH	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412535	25918841	AL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412535	25918841	AP	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412535	25918841	CMvD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412535	25918841	CMvD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412535	25918841	CMvD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412535	25918841	CMvD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412535	25918841	CP	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412535	25918841	FR	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412535	25918841	GGK	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412535	25918841	GGK	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412535	25918841	GGK	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412535	25918841	HB	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412535	25918841	IZ	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412535	25918841	IZ	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412535	25918841	JB	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412535	25918841	JLL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412535	25918841	JPB	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412535	25918841	MC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412535	25918841	MC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412535	25918841	MC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412535	25918841	MP	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412535	25918841	MP	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412535	25918841	MTB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412535	25918841	MTB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412535	25918841	MTB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412535	25918841	O. Calero	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4412535	25918841	O. Combarros	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412535	25918841	O. Combarros	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412535	25918841	PSJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412535	25918841	PSJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412535	25918841	PSJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412535	25918841	RGW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412535	25918841	RGW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412535	25918841	RGW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412535	25918841	RSGK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412535	25918841	RSGK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412535	25918841	RSGK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412535	25918841	SH	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412535	25918841	SJC	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412535	25918841	SJC	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412535	25918841	SJvdL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4412535	25918841	SJvdL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412535	25918841	TS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412535	25918841	VL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412535	25918841	YSA	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412535	25918841	YSA	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4230810	25401079	AAG	2	conceived the study, participated in its design and coordination, helped to interpret the data and write the manuscript	conceived the study, participated in its design and coordination, helped to interpret the data and write the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Project administration|Writing - Original Draft	YES
4230810	25401079	NK	2	conducted the transformation experiments and prepared figures 2 3	conducted the transformation experiments and prepared figures 2 3	Performed the experiments	Investigation|Visualization	YES
4230810	25401079	SNS	2	performed many types of experiments to produce protoplasts and transform them, actively participated in the design of the study and drafted a preliminary manuscript containing figures 1 and 3	performed many types of experiments to produce protoplasts and transform them, actively participated in the design of the study and drafted a preliminary manuscript containing figures 1 and 3	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Visualization|Writing - Original Draft	YES
4230810	25401079	TB	2	prepared many batches of protoplasts	prepared many batches of protoplasts	-	-	NO
4230810	25401079	WJB	2	shaped the presentation of the material written	shaped the presentation of the material written	Wrote the paper	Writing - Original Draft	YES
5510298	28744360	AM	7	Contributions to the conception or design of the work|analysis and interpretation of data|final approval of article	Contributions to the conception or design of the work	Conceived and designed the experiments	Conceptualization	YES
5510298	28744360	AM	7	Contributions to the conception or design of the work|analysis and interpretation of data|final approval of article	analysis and interpretation of data	Analyzed the data	Formal analysis	YES
5510298	28744360	AM	7	Contributions to the conception or design of the work|analysis and interpretation of data|final approval of article	final approval of article	-	-	NO
5510298	28744360	AN	7	analysis and interpretation of data|drafting the article	analysis and interpretation of data	Analyzed the data	Formal analysis	YES
5510298	28744360	AN	7	analysis and interpretation of data|drafting the article	drafting the article	Wrote the paper	Writing - Original Draft	YES
5510298	28744360	BY	7	Contributions to the conception or design of the work|final approval of article	Contributions to the conception or design of the work	Conceived and designed the experiments	Conceptualization	YES
5510298	28744360	BY	7	Contributions to the conception or design of the work|final approval of article	final approval of article	-	-	NO
5510298	28744360	HM	7	analysis and interpretation of data|final approval of article	analysis and interpretation of data	Analyzed the data	Formal analysis	YES
5510298	28744360	HM	7	analysis and interpretation of data|final approval of article	final approval of article	-	-	NO
5510298	28744360	SF	7	Contributions to the conception or design of the work|analysis and interpretation of data	Contributions to the conception or design of the work	Conceived and designed the experiments	Conceptualization	YES
5510298	28744360	SF	7	Contributions to the conception or design of the work|analysis and interpretation of data	analysis and interpretation of data	Analyzed the data	Formal analysis	YES
5510298	28744360	TM	7	Contributions to the conception or design of the work|analysis and interpretation of data|final approval of article	Contributions to the conception or design of the work	Conceived and designed the experiments	Conceptualization	YES
5510298	28744360	TM	7	Contributions to the conception or design of the work|analysis and interpretation of data|final approval of article	analysis and interpretation of data	Analyzed the data	Formal analysis	YES
5510298	28744360	TM	7	Contributions to the conception or design of the work|analysis and interpretation of data|final approval of article	final approval of article	-	-	NO
2896923	20507554	LK	2	played an important role in study design, data collection and data interpretation and manuscript preparation	played an important role in study design, data collection and data interpretation and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
2896923	20507554	MH	2	was the primary author of the manuscript and participated in the design of the study and carried out the data collection, data analysis, statistical analysis and interpretation of the results	was the primary author of the manuscript and participated in the design of the study and carried out the data collection, data analysis, statistical analysis and interpretation of the results	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
2896923	20507554	YP	2	played an important role in study design, data collection and interpretation and study coordination	played an important role in study design, data collection and interpretation and study coordination	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology|Project administration	YES
5553748	28797224	IBHW	2	contributed to the study design|prepared the manuscript	contributed to the study design	Conceived and designed the experiments	Methodology	YES
5553748	28797224	IBHW	2	contributed to the study design|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5553748	28797224	JWM	2	performed sequencing data analysis|prepared the manuscript	performed sequencing data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5553748	28797224	JWM	2	performed sequencing data analysis|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5553748	28797224	MD	2	performed experimental evolution, growth characterization, cloning experiments and conceived of the study|prepared the manuscript	performed experimental evolution, growth characterization, cloning experiments and conceived of the study	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5553748	28797224	MD	2	performed experimental evolution, growth characterization, cloning experiments and conceived of the study|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5694217	29181012	JA	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5694217	29181012	JE	PLoS52	dicussed the results and wrote the manuscript	dicussed the results and wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5694217	29181012	MC	PLoS52	programmed the experiments|dicussed the results and wrote the manuscript	programmed the experiments	Contributed reagents/materials/analysis tools	Software	YES
5694217	29181012	MC	PLoS52	programmed the experiments|dicussed the results and wrote the manuscript	dicussed the results and wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5694217	29181012	ME	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5694217	29181012	PA	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5694217	29181012	VC	PLoS52	analyzed and discussed the phylogenetic data	analyzed and discussed the phylogenetic data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4412536	25919000	CXL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412536	25919000	GXN	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412536	25919000	WTX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412536	25919000	WTX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4412536	25919000	WTX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4412536	25919000	WZH	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412536	25919000	XCZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412536	25919000	XCZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412536	25919000	XCZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412536	25919000	XCZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412536	25919000	XPX	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412536	25919000	XPX	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412536	25919000	XPX	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412536	25919000	YYC	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412536	25919000	YYC	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4230811	25401073	HT	2	designed and performed experiments	designed and performed experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4230811	25401073	JD	2	analyzed data|participated in the design and coordination of this study and drafted the manuscript	analyzed data	Analyzed the data	Formal analysis	YES
4230811	25401073	JD	2	analyzed data|participated in the design and coordination of this study and drafted the manuscript	participated in the design and coordination of this study and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft	YES
4230811	25401073	MIsh	2	designed and performed experiments	designed and performed experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4230811	25401073	MIto	2	designed and performed experiments	designed and performed experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4230811	25401073	MT	2	participated in the design and coordination of this study and drafted the manuscript	participated in the design and coordination of this study and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft	YES
4230811	25401073	RM	2	designed and performed experiments	designed and performed experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4230811	25401073	YNag	2	participated in the design and coordination of this study and drafted the manuscript|conceived the study and is the responsible of the entire project	participated in the design and coordination of this study and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft	YES
4230811	25401073	YNag	2	participated in the design and coordination of this study and drafted the manuscript|conceived the study and is the responsible of the entire project	conceived the study and is the responsible of the entire project	Conceived and designed the experiments	Conceptualization	YES
4230811	25401073	YNit	2	designed and performed experiments	designed and performed experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4230811	25401073	YO	2	participated in the design of the study	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
4230811	25401073	ZP	2	analyzed data|participated in the design and coordination of this study and drafted the manuscript	analyzed data	Analyzed the data	Formal analysis	YES
4230811	25401073	ZP	2	analyzed data|participated in the design and coordination of this study and drafted the manuscript	participated in the design and coordination of this study and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft	YES
5510299	28744361	AH	2	helped to draft the manuscript	helped to draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5510299	28744361	All authors	2	read and approved the final text	read and approved the final text	-	-	NO
5510299	28744361	BK	2	contributed to the laboratory work and assisted in drafting the manuscript	contributed to the laboratory work and assisted in drafting the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5510299	28744361	LG	2	conducted the experimental laboratory work, analysed and interpreted the data and wrote the manuscript|are designated as guarantors	conducted the experimental laboratory work, analysed and interpreted the data and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5510299	28744361	LG	2	conducted the experimental laboratory work, analysed and interpreted the data and wrote the manuscript|are designated as guarantors	are designated as guarantors	Conceived and designed the experiments	-	YES
5510299	28744361	MC	2	originated the study, participated in its study design and coordination and helped to draft the manuscript|are designated as guarantors	originated the study, participated in its study design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
5510299	28744361	MC	2	originated the study, participated in its study design and coordination and helped to draft the manuscript|are designated as guarantors	are designated as guarantors	Conceived and designed the experiments	-	YES
5510299	28744361	MK	2	contributed to the laboratory work and assisted in drafting the manuscript	contributed to the laboratory work and assisted in drafting the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5510299	28744361	RB	2	contributed to the laboratory work and assisted in drafting the manuscript	contributed to the laboratory work and assisted in drafting the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5510299	28744361	RR	2	participated in the study coordination and helped to draft the manuscript	participated in the study coordination and helped to draft the manuscript	Wrote the paper	Project administration|Writing - Original Draft	YES
5360745	28324340	DT	2	gave advice in the data interpretation and reviewed the manuscript	gave advice in the data interpretation and reviewed the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5360745	28324340	EC	2	recruited the patients and reviewed the manuscript	recruited the patients and reviewed the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5360745	28324340	JS	2	analyzed the pet data and wrote the manuscript	analyzed the pet data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5360745	28324340	LE	2	assisted with the analyses and reviewed the manuscript	assisted with the analyses and reviewed the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5360745	28324340	MC	2	was integral in developing the study concept and reviewed the manuscript	was integral in developing the study concept and reviewed the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
5360745	28324340	MS	2	assisted with the imaging protocol	assisted with the imaging protocol	Conceived and designed the experiments|Analyzed the data	Methodology|Visualization	YES
5360745	28324340	SR	2	facilitated the correlation of the imaging and histologic registration	facilitated the correlation of the imaging and histologic registration	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
5360745	28324340	TT	2	performed the histologic analyses	performed the histologic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5360745	28324340	ZW	2	assisted with the imaging protocol	assisted with the imaging protocol	Conceived and designed the experiments|Analyzed the data	Methodology|Visualization	YES
1855430	17502914	JY	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1855430	17502914	JY	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1855430	17502914	JY	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1855430	17502914	JY	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1855430	17502914	KY	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1855430	17502914	KY	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1855430	17502914	YC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1855430	17502914	YC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1855430	17502914	YC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1855430	17502914	YT	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1855430	17502914	YT	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1855430	17502914	YY	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1855430	17502914	YY	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1855430	17502914	YY	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1855430	17502914	YY	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5553760	28797230	G. Sahana	2	contributed to the study design and drafted the manuscript	contributed to the study design and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5553760	28797230	G. Su	2	contributed to the study design and drafted the manuscript	contributed to the study design and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5553760	28797230	LF	2	carried out the main statistical analyses, wrote the manuscript, and conceived and designed the study	carried out the main statistical analyses, wrote the manuscript, and conceived and designed the study	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5553760	28797230	ML	2	contributed to the study design and drafted the manuscript	contributed to the study design and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5553760	28797230	PM	2	carried out the gwas analyses	carried out the gwas analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5553760	28797230	PS	2	conceived and designed the study and drafted the manuscript	conceived and designed the study and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
5553760	28797230	SZ	2	contributed to the study design and drafted the manuscript	contributed to the study design and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5553760	28797230	YY	2	contributed to the study design and drafted the manuscript	contributed to the study design and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
2909922	20587040	The authors	2	contributed equally with the inception and writing of the manuscript	contributed equally with the inception and writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5694442	29184562	GK	2	conceived and designed the research, interpreted the data, and critically revised the manuscript	conceived and designed the research, interpreted the data, and critically revised the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Review & Editing	YES
5694442	29184562	HS	2	analyzed and interpreted the data, and critically revised the manuscript	analyzed and interpreted the data, and critically revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5694442	29184562	KB	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5694442	29184562	ML	2	designed the research, performed experiments, analyzed and interpreted the data, and wrote the manuscript	designed the research, performed experiments, analyzed and interpreted the data, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5694442	29184562	PW	2	designed the research and critically revised the manuscript	designed the research and critically revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5694442	29184562	TH	2	designed the research and critically revised the manuscript	designed the research and critically revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5694442	29184562	UG	2	designed the research, analyzed and interpreted the data, and critically revised the manuscript	designed the research, analyzed and interpreted the data, and critically revised the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
4230812	25401061	CF	2	including the parameter estimation for equation 1	including the parameter estimation for equation 1	Analyzed the data	Formal analysis	YES
4230812	25401061	DLF	2	conceived of the study, and participated in its design and coordination and helped to draft the manuscript	conceived of the study, and participated in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
4412537	25919313	JF	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412537	25919313	JF	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412537	25919313	JF	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412537	25919313	JF	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412537	25919313	JMN	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412537	25919313	JMN	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412537	25919313	JMN	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412537	25919313	JMN	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412537	25919313	RAF	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412537	25919313	RAF	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412537	25919313	SDET	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412537	25919313	SDET	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412537	25919313	SDET	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412537	25919313	SDET	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412537	25919313	SSF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412537	25919313	SSF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412537	25919313	SSF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412537	25919313	SSF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2909923	20609257	DD	2	participated in protocol design, sample analyses and manuscript preparation	participated in protocol design, sample analyses and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
2909923	20609257	HH	2	participated in data collection, sample analysis and manuscript review	participated in data collection, sample analysis and manuscript review	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
2909923	20609257	JS	2	participated in data collection, sample analysis and manuscript review	participated in data collection, sample analysis and manuscript review	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
2909923	20609257	PB	2	participated in participant recruitment data collection, and manuscript review	participated in participant recruitment data collection, and manuscript review	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
2909923	20609257	RCH	2	participated in protocol design, conduct of the study, data analysis and manuscript preparation	participated in protocol design, conduct of the study, data analysis and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5674652	29152207	AM	7	Contributions to the conception or design of the work|interpretation of data|Final approval of the manuscript	Contributions to the conception or design of the work	Conceived and designed the experiments	Conceptualization	YES
5674652	29152207	AM	7	Contributions to the conception or design of the work|interpretation of data|Final approval of the manuscript	interpretation of data	Analyzed the data	Formal analysis	YES
5674652	29152207	AM	7	Contributions to the conception or design of the work|interpretation of data|Final approval of the manuscript	Final approval of the manuscript	-	-	NO
5674652	29152207	BM	7	Contributions to the acquisition and analysis of data for the work and Drafting the article	Contributions to the acquisition and analysis of data for the work and Drafting the article	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft	YES
5674652	29152207	EM	7	Contributions to the conception or design of the work|Final approval of the manuscript	Contributions to the conception or design of the work	Conceived and designed the experiments	Conceptualization	YES
5674652	29152207	EM	7	Contributions to the conception or design of the work|Final approval of the manuscript	Final approval of the manuscript	-	-	NO
5674652	29152207	GN	7	Contributions to the conception or design of the work|interpretation of data|Final approval of the manuscript	Contributions to the conception or design of the work	Conceived and designed the experiments	Conceptualization	YES
5674652	29152207	GN	7	Contributions to the conception or design of the work|interpretation of data|Final approval of the manuscript	interpretation of data	Analyzed the data	Formal analysis	YES
5674652	29152207	GN	7	Contributions to the conception or design of the work|interpretation of data|Final approval of the manuscript	Final approval of the manuscript	-	-	NO
5674652	29152207	HM	7	Contributions to the conception or design of the work|interpretation of data|Final approval of the manuscript	Contributions to the conception or design of the work	Conceived and designed the experiments	Conceptualization	YES
5674652	29152207	HM	7	Contributions to the conception or design of the work|interpretation of data|Final approval of the manuscript	interpretation of data	Analyzed the data	Formal analysis	YES
5674652	29152207	HM	7	Contributions to the conception or design of the work|interpretation of data|Final approval of the manuscript	Final approval of the manuscript	-	-	NO
1855431	17502915	AL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1855431	17502915	AM	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1855431	17502915	AM	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1855431	17502915	BL	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1855431	17502915	BL	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1855431	17502915	CB	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1855431	17502915	CB	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1855431	17502915	CT	PLoS5	Revision of the first draft	Revision of the first draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
1855431	17502915	DS	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1855431	17502915	EH	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1855431	17502915	FL	PLoS5	Revision of the first draft	Revision of the first draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
1855431	17502915	JS	PLoS5	Revision of the paper	Revision of the paper	Wrote the paper	Writing - Review & Editing	YES
1855431	17502915	KB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1855431	17502915	RR	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1855431	17502915	ZW	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1855431	17502915	ZW	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5360749	28324341	J. All	2	authors participated in drafting and revising this paper	authors participated in drafting and revising this paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5553782	28797240	EK	2	contributed code|assisted with the computational analyses	contributed code	Contributed reagents/materials/analysis tools	Software	YES
5553782	28797240	EK	2	contributed code|assisted with the computational analyses	assisted with the computational analyses	Analyzed the data	Formal analysis	YES
5553782	28797240	ER	2	performed all mouse and qpcr experiments|assisted with the computational analyses	performed all mouse and qpcr experiments	Performed the experiments	Investigation	YES
5553782	28797240	ER	2	performed all mouse and qpcr experiments|assisted with the computational analyses	assisted with the computational analyses	Analyzed the data	Formal analysis	YES
5553782	28797240	ET	2	performed the ion torrent library preparation and sequencing	performed the ion torrent library preparation and sequencing	Performed the experiments	Investigation	YES
5553782	28797240	GB	2	contributed code|assisted with the computational analyses	contributed code	Contributed reagents/materials/analysis tools	Software	YES
5553782	28797240	GB	2	contributed code|assisted with the computational analyses	assisted with the computational analyses	Analyzed the data	Formal analysis	YES
5553782	28797240	GG	2	conceived of the research|wrote the manuscript	conceived of the research	Conceived and designed the experiments	Conceptualization	YES
5553782	28797240	GG	2	conceived of the research|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5553782	28797240	JS	2	conceived of the research|performed the illumina library preparation and sequencing|wrote the manuscript	conceived of the research	Conceived and designed the experiments	Conceptualization	YES
5553782	28797240	JS	2	conceived of the research|performed the illumina library preparation and sequencing|wrote the manuscript	performed the illumina library preparation and sequencing	Performed the experiments	Investigation	YES
5553782	28797240	JS	2	conceived of the research|performed the illumina library preparation and sequencing|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5553782	28797240	KH	2	contributed code|assisted with the computational analyses	contributed code	Contributed reagents/materials/analysis tools	Software	YES
5553782	28797240	KH	2	contributed code|assisted with the computational analyses	assisted with the computational analyses	Analyzed the data	Formal analysis	YES
5553782	28797240	NL	2	developed and performed computational analyses|wrote the manuscript	developed and performed computational analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5553782	28797240	NL	2	developed and performed computational analyses|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5553782	28797240	OS	2	performed the illumina library preparation and sequencing	performed the illumina library preparation and sequencing	Performed the experiments	Investigation	YES
5553782	28797240	TG	2	conceived of the research|performed the ion torrent library preparation and sequencing|wrote the manuscript	conceived of the research	Conceived and designed the experiments	Conceptualization	YES
5553782	28797240	TG	2	conceived of the research|performed the ion torrent library preparation and sequencing|wrote the manuscript	performed the ion torrent library preparation and sequencing	Performed the experiments	Investigation	YES
5553782	28797240	TG	2	conceived of the research|performed the ion torrent library preparation and sequencing|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
2915951	20642826	BLB	2	made substantial contributions to data acquisition	made substantial contributions to data acquisition	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
2915951	20642826	BPM	2	made substantial contributions to data acquisition	made substantial contributions to data acquisition	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
2915951	20642826	CMM	2	was the primary investigator, obtained grant funds for the project, and supervised all study recruitment, data acquisition, data specimen analysis, and manuscript preparation|designed the study protocol|were also involved in manuscript writing and preparation	was the primary investigator, obtained grant funds for the project, and supervised all study recruitment, data acquisition, data specimen analysis, and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Funding acquisition|Investigation|Supervision|Writing - Original Draft	YES
2915951	20642826	CMM	2	was the primary investigator, obtained grant funds for the project, and supervised all study recruitment, data acquisition, data specimen analysis, and manuscript preparation|designed the study protocol|were also involved in manuscript writing and preparation	designed the study protocol	Conceived and designed the experiments	Methodology	YES
2915951	20642826	CMM	2	was the primary investigator, obtained grant funds for the project, and supervised all study recruitment, data acquisition, data specimen analysis, and manuscript preparation|designed the study protocol|were also involved in manuscript writing and preparation	were also involved in manuscript writing and preparation	Wrote the paper	Writing - Original Draft	YES
2915951	20642826	DLH	2	made substantial contributions to data acquisition	made substantial contributions to data acquisition	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
2915951	20642826	ECL	2	made substantial contributions to data acquisition|performed the statistical analysis and was primarily responsible for writing the manuscript	made substantial contributions to data acquisition	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
2915951	20642826	ECL	2	made substantial contributions to data acquisition|performed the statistical analysis and was primarily responsible for writing the manuscript	performed the statistical analysis and was primarily responsible for writing the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
2915951	20642826	JSV	2	made substantial contributions to interpretation of data	made substantial contributions to interpretation of data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
2915951	20642826	LEA	2	made substantial contributions to interpretation of data	made substantial contributions to interpretation of data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
2915951	20642826	LMY	2	made substantial contributions to data acquisition|were also involved in manuscript writing and preparation	made substantial contributions to data acquisition	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
2915951	20642826	LMY	2	made substantial contributions to data acquisition|were also involved in manuscript writing and preparation	were also involved in manuscript writing and preparation	Wrote the paper	Writing - Original Draft	YES
2915951	20642826	SASC	2	were also involved in manuscript writing and preparation	were also involved in manuscript writing and preparation	Wrote the paper	Writing - Original Draft	YES
2915951	20642826	WJK	2	designed the study protocol|were also involved in manuscript writing and preparation	designed the study protocol	Conceived and designed the experiments	Methodology	YES
2915951	20642826	WJK	2	designed the study protocol|were also involved in manuscript writing and preparation	were also involved in manuscript writing and preparation	Wrote the paper	Writing - Original Draft	YES
5694490	29184561	CL	1	Project concept and design|Mutant identification|Genotyping	Project concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5694490	29184561	CL	1	Project concept and design|Mutant identification|Genotyping	Mutant identification	Performed the experiments	Investigation	YES
5694490	29184561	CL	1	Project concept and design|Mutant identification|Genotyping	Genotyping	Performed the experiments	Investigation	YES
5694490	29184561	CT	1	Genotyping	Genotyping	Performed the experiments	Investigation	YES
5694490	29184561	DW	1	Mutant identification	Mutant identification	Performed the experiments	Investigation	YES
5694490	29184561	FY	1	Project concept and design|Genotyping	Project concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5694490	29184561	FY	1	Project concept and design|Genotyping	Genotyping	Performed the experiments	Investigation	YES
5694490	29184561	RW	1	Genotyping	Genotyping	Performed the experiments	Investigation	YES
5694490	29184561	SB	1	Population development|Field trial	Population development	-	-	NO
5694490	29184561	SB	1	Population development|Field trial	Field trial	-	-	NO
5694490	29184561	SW	1	Population development|Field trial	Population development	-	-	NO
5694490	29184561	SW	1	Population development|Field trial	Field trial	-	-	NO
5694490	29184561	WZ	1	Project concept and design	Project concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5694490	29184561	X-QZ	1	Population development|Field trial|Genotyping	Population development	-	-	NO
5694490	29184561	X-QZ	1	Population development|Field trial|Genotyping	Field trial	-	-	NO
5694490	29184561	X-QZ	1	Population development|Field trial|Genotyping	Genotyping	Performed the experiments	Investigation	YES
5694490	29184561	YX	1	Project concept and design	Project concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4584062	26448931	Chong Ma	2	contributed equally to this work	contributed equally to this work	-	-	NO
4584062	26448931	Lei Cao	2	contributed equally to this work	contributed equally to this work	-	-	NO
4412538	25919700	FGT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412538	25919700	FGT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412538	25919700	FGT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412538	25919700	PC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412538	25919700	PC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412538	25919700	PC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412538	25919700	PC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412538	25919700	YCL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412538	25919700	YCL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412538	25919700	YCL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4230813	25401060	DBL	2	also prepared the final draft of the manuscript for submission	also prepared the final draft of the manuscript for submission	Wrote the paper	Writing - Original Draft	YES
4230813	25401060	JF	2	assisted pks with the genome analyses	assisted pks with the genome analyses	Analyzed the data	Formal analysis	YES
4230813	25401060	PKSs	2	direct supervisor	direct supervisor	-	Supervision	YES
5553784	28797239	EM	PLoS52	performed rna extractions	performed rna extractions	Performed the experiments	Investigation	YES
5553784	28797239	JT	PLoS52	were responsible for the experimental protocols and generation of animal material	were responsible for the experimental protocols and generation of animal material	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5553784	28797239	MA	PLoS52	designed the experiment|wrote the paper	designed the experiment	Conceived and designed the experiments	Methodology	YES
5553784	28797239	MA	PLoS52	designed the experiment|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5553784	28797239	MG	PLoS52	were responsible for the experimental protocols and generation of animal material	were responsible for the experimental protocols and generation of animal material	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5553784	28797239	OG	PLoS52	performed the kinetic study	performed the kinetic study	Performed the experiments	Investigation	YES
5553784	28797239	RGP	PLoS52	performed the kinetic study	performed the kinetic study	Performed the experiments	Investigation	YES
5553784	28797239	RQ	PLoS52	designed the experiment|were responsible for the experimental protocols and generation of animal material	designed the experiment	Conceived and designed the experiments	Methodology	YES
5553784	28797239	RQ	PLoS52	designed the experiment|were responsible for the experimental protocols and generation of animal material	were responsible for the experimental protocols and generation of animal material	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5553784	28797239	TFC	PLoS52	performed rna extractions|analysed the data|wrote the paper	performed rna extractions	Performed the experiments	Investigation	YES
5553784	28797239	TFC	PLoS52	performed rna extractions|analysed the data|wrote the paper	analysed the data	Analyzed the data	Formal analysis	YES
5553784	28797239	TFC	PLoS52	performed rna extractions|analysed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5553784	28797239	all authors	PLoS52	contributed to the obtaining of biological samples|read and approved the manuscript	contributed to the obtaining of biological samples	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5553784	28797239	all authors	PLoS52	contributed to the obtaining of biological samples|read and approved the manuscript	read and approved the manuscript	-	-	NO
5364119	28337725	HY	2	provided technical support for phase analysis	provided technical support for phase analysis	Performed the experiments	Investigation	YES
5364119	28337725	KN	2	edited it|confirmed it|participated in the conception and study design	edited it	Wrote the paper	Writing - Review & Editing	YES
5364119	28337725	KN	2	edited it|confirmed it|participated in the conception and study design	confirmed it	-	-	NO
5364119	28337725	KN	2	edited it|confirmed it|participated in the conception and study design	participated in the conception and study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5364119	28337725	KO	2	performed data analysis and interpretation	performed data analysis and interpretation	Analyzed the data	Formal analysis	YES
5364119	28337725	MH	2	participated in the conception and study design	participated in the conception and study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5364119	28337725	MO	2	provided technical support for phase analysis	provided technical support for phase analysis	Performed the experiments	Investigation	YES
5364119	28337725	SK	2	performed data analysis and interpretation|participated in the conception and study design	performed data analysis and interpretation	Analyzed the data	Formal analysis	YES
5364119	28337725	SK	2	performed data analysis and interpretation|participated in the conception and study design	participated in the conception and study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5364119	28337725	SM	2	performed data analysis and interpretation	performed data analysis and interpretation	Analyzed the data	Formal analysis	YES
5364119	28337725	TS	2	provided technical support for phase analysis	provided technical support for phase analysis	Performed the experiments	Investigation	YES
1855432	17487271	AP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1855432	17487271	AP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1855432	17487271	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1855432	17487271	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1855432	17487271	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1855432	17487271	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1855432	17487271	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1855432	17487271	BS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1855432	17487271	BS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1855432	17487271	CS	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1855432	17487271	JA	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1855432	17487271	JA	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1855432	17487271	JM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1855432	17487271	JM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1855432	17487271	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1855432	17487271	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1855432	17487271	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1855432	17487271	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1855432	17487271	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1855432	17487271	RA	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1855432	17487271	TS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
2936297	20727213	CK	2	was involved in the conception of the study, data interpretation, literature review, and drafting of the manuscript	was involved in the conception of the study, data interpretation, literature review, and drafting of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
2936297	20727213	PGS	2	made substantial contributions to the experimental design, data acquisition, interpretation of the data and drafting of the manuscript	made substantial contributions to the experimental design, data acquisition, interpretation of the data and drafting of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
2936297	20727213	RW	2	made major contributions to the experimental design, data acquisition, and interpretation of the data	made major contributions to the experimental design, data acquisition, and interpretation of the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Methodology|Resources	YES
2936297	20727213	SJS	2	contributed to the conception of the study, interpretation of the data, and drafting of the manuscript	contributed to the conception of the study, interpretation of the data, and drafting of the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Resources|Writing - Original Draft	YES
4584063	26448942	Lin Wang	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
4584063	26448942	Wei Zhang	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
4478971	25846554	Both authors	2	contributed equally to the study	contributed equally to the study	-	-	NO
4412539	25919031	ERA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412539	25919031	ERA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412539	25919031	ERA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412539	25919031	EVS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4412539	25919031	EVS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4412539	25919031	IVA	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4412539	25919031	IVA	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4412539	25919031	LBB	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412539	25919031	LBB	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412539	25919031	PIB	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4412539	25919031	PIB	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412539	25919031	SVB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4412539	25919031	SVB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412539	25919031	YAR	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4412539	25919031	YAR	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5674654	29152209	EFF	7	Contributions to the conception or design of the work|interpretation of data|contributions to the acquisition and analysis of data for the work, and drafting the article|manuscript edition|final approval of the article	Contributions to the conception or design of the work	Conceived and designed the experiments	Conceptualization	YES
5674654	29152209	EFF	7	Contributions to the conception or design of the work|interpretation of data|contributions to the acquisition and analysis of data for the work, and drafting the article|manuscript edition|final approval of the article	interpretation of data	Analyzed the data	Formal analysis	YES
5674654	29152209	EFF	7	Contributions to the conception or design of the work|interpretation of data|contributions to the acquisition and analysis of data for the work, and drafting the article|manuscript edition|final approval of the article	contributions to the acquisition and analysis of data for the work, and drafting the article	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft	YES
5674654	29152209	EFF	7	Contributions to the conception or design of the work|interpretation of data|contributions to the acquisition and analysis of data for the work, and drafting the article|manuscript edition|final approval of the article	manuscript edition	Wrote the paper	Writing - Review & Editing	YES
5674654	29152209	EFF	7	Contributions to the conception or design of the work|interpretation of data|contributions to the acquisition and analysis of data for the work, and drafting the article|manuscript edition|final approval of the article	final approval of the article	-	-	NO
5674654	29152209	JL	7	Contributions to the conception or design of the work|contributions to the acquisition and analysis of data for the work, and drafting the article|final approval of the article	Contributions to the conception or design of the work	Conceived and designed the experiments	Conceptualization	YES
5674654	29152209	JL	7	Contributions to the conception or design of the work|contributions to the acquisition and analysis of data for the work, and drafting the article|final approval of the article	contributions to the acquisition and analysis of data for the work, and drafting the article	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft	YES
5674654	29152209	JL	7	Contributions to the conception or design of the work|contributions to the acquisition and analysis of data for the work, and drafting the article|final approval of the article	final approval of the article	-	-	NO
5674654	29152209	KWVM	7	Contributions to the conception or design of the work|contributions to the acquisition and analysis of data for the work, and drafting the article|final approval of the article	Contributions to the conception or design of the work	Conceived and designed the experiments	Conceptualization	YES
5674654	29152209	KWVM	7	Contributions to the conception or design of the work|contributions to the acquisition and analysis of data for the work, and drafting the article|final approval of the article	contributions to the acquisition and analysis of data for the work, and drafting the article	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft	YES
5674654	29152209	KWVM	7	Contributions to the conception or design of the work|contributions to the acquisition and analysis of data for the work, and drafting the article|final approval of the article	final approval of the article	-	-	NO
5674654	29152209	PGH	7	Contributions to the conception or design of the work|interpretation of data|contributions to the acquisition and analysis of data for the work, and drafting the article|manuscript edition|final approval of the article	Contributions to the conception or design of the work	Conceived and designed the experiments	Conceptualization	YES
5674654	29152209	PGH	7	Contributions to the conception or design of the work|interpretation of data|contributions to the acquisition and analysis of data for the work, and drafting the article|manuscript edition|final approval of the article	interpretation of data	Analyzed the data	Formal analysis	YES
5674654	29152209	PGH	7	Contributions to the conception or design of the work|interpretation of data|contributions to the acquisition and analysis of data for the work, and drafting the article|manuscript edition|final approval of the article	contributions to the acquisition and analysis of data for the work, and drafting the article	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft	YES
5674654	29152209	PGH	7	Contributions to the conception or design of the work|interpretation of data|contributions to the acquisition and analysis of data for the work, and drafting the article|manuscript edition|final approval of the article	manuscript edition	Wrote the paper	Writing - Review & Editing	YES
5674654	29152209	PGH	7	Contributions to the conception or design of the work|interpretation of data|contributions to the acquisition and analysis of data for the work, and drafting the article|manuscript edition|final approval of the article	final approval of the article	-	-	NO
5674654	29152209	SRA	7	Contributions to the conception or design of the work|interpretation of data|contributions to the acquisition and analysis of data for the work, and drafting the article|manuscript edition|final approval of the article	Contributions to the conception or design of the work	Conceived and designed the experiments	Conceptualization	YES
5674654	29152209	SRA	7	Contributions to the conception or design of the work|interpretation of data|contributions to the acquisition and analysis of data for the work, and drafting the article|manuscript edition|final approval of the article	interpretation of data	Analyzed the data	Formal analysis	YES
5674654	29152209	SRA	7	Contributions to the conception or design of the work|interpretation of data|contributions to the acquisition and analysis of data for the work, and drafting the article|manuscript edition|final approval of the article	contributions to the acquisition and analysis of data for the work, and drafting the article	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft	YES
5674654	29152209	SRA	7	Contributions to the conception or design of the work|interpretation of data|contributions to the acquisition and analysis of data for the work, and drafting the article|manuscript edition|final approval of the article	manuscript edition	Wrote the paper	Writing - Review & Editing	YES
5674654	29152209	SRA	7	Contributions to the conception or design of the work|interpretation of data|contributions to the acquisition and analysis of data for the work, and drafting the article|manuscript edition|final approval of the article	final approval of the article	-	-	NO
5694491	29184566	AA	PLoS52	conducted experiments|analyzed the data|drafted the manuscript	conducted experiments	Performed the experiments	Investigation	YES
5694491	29184566	AA	PLoS52	conducted experiments|analyzed the data|drafted the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5694491	29184566	AA	PLoS52	conducted experiments|analyzed the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5694491	29184566	AS	PLoS52	conducted experiments|analyzed the data|drafted the manuscript	conducted experiments	Performed the experiments	Investigation	YES
5694491	29184566	AS	PLoS52	conducted experiments|analyzed the data|drafted the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5694491	29184566	AS	PLoS52	conducted experiments|analyzed the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5694491	29184566	AZ	PLoS52	conducted experiments|analyzed the data	conducted experiments	Performed the experiments	Investigation	YES
5694491	29184566	AZ	PLoS52	conducted experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5694491	29184566	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5694491	29184566	IT	PLoS52	designed and conceived the study|analyzed the data|critically revised the manuscript	designed and conceived the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5694491	29184566	IT	PLoS52	designed and conceived the study|analyzed the data|critically revised the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5694491	29184566	IT	PLoS52	designed and conceived the study|analyzed the data|critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5694491	29184566	LL	PLoS52	designed and conceived the study|critically revised the manuscript	designed and conceived the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5694491	29184566	LL	PLoS52	designed and conceived the study|critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5694491	29184566	VZ	PLoS52	designed and conceived the study|analyzed the data|drafted the manuscript	designed and conceived the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5694491	29184566	VZ	PLoS52	designed and conceived the study|analyzed the data|drafted the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5694491	29184566	VZ	PLoS52	designed and conceived the study|analyzed the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4230814	25401075	DDL	2	conceived and designed the study, supervised the research group, provided funding support, drafted and revised the manuscript	conceived and designed the study, supervised the research group, provided funding support, drafted and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Funding acquisition|Methodology|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
4230814	25401075	NL	2	designed and undertook decoloration studies in the presence of chelators	designed and undertook decoloration studies in the presence of chelators	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4230814	25401075	PRC	2	designed and performed decoloration and enzyme assays and helped draft the manuscript	designed and performed decoloration and enzyme assays and helped draft the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
2955583	20860817	AH	2	helped conceive the study, participated in the study design and in the exercise sessions, helped with the strength measurements and helped to draft the manuscript	helped conceive the study, participated in the study design and in the exercise sessions, helped with the strength measurements and helped to draft the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Writing - Original Draft	YES
2955583	20860817	CS	2	participated in the design of the study and the exercise sessions, and helped with the enzyme analyses and drafting of the manuscript	participated in the design of the study and the exercise sessions, and helped with the enzyme analyses and drafting of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
2955583	20860817	ER	2	participated in the design of the study, helped with the enzyme analyses, and drafting of the manuscript	participated in the design of the study, helped with the enzyme analyses, and drafting of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
2955583	20860817	MC	2	conceived the study, carried out the exercise sessions and all analyses, and drafted the manuscript	conceived the study, carried out the exercise sessions and all analyses, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
2955583	20860817	PC	2	participated in the study design, participated in the exercise sessions and helped to draft the manuscript	participated in the study design, participated in the exercise sessions and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3821950	24260019	Fadi Chen	2	equally contributed to this work and should be considered as cocorresponding authors	equally contributed to this work and should be considered as cocorresponding authors	-	-	NO
3821950	24260019	Weimin Fang	2	equally contributed to this work and should be considered as cocorresponding authors	equally contributed to this work and should be considered as cocorresponding authors	-	-	NO
5364122	28337724	CK	2	contributed to the acquisition of data|contributed to the analysis and interpretation of data	contributed to the acquisition of data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5364122	28337724	CK	2	contributed to the acquisition of data|contributed to the analysis and interpretation of data	contributed to the analysis and interpretation of data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5364122	28337724	KA	2	contributed to the analysis and interpretation of data|contributed to the drafting of the manuscript	contributed to the analysis and interpretation of data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5364122	28337724	KA	2	contributed to the analysis and interpretation of data|contributed to the drafting of the manuscript	contributed to the drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
5364122	28337724	KH	2	contributed to the acquisition of data	contributed to the acquisition of data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5364122	28337724	KI	2	contributed to the study conception and design	contributed to the study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5364122	28337724	KK	2	contributed to the acquisition of data	contributed to the acquisition of data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5364122	28337724	NT	2	contributed to the study conception and design	contributed to the study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5364122	28337724	TS	2	contributed to the study conception and design|contributed to the acquisition of data|contributed to the analysis and interpretation of data|contributed to the critical revision	contributed to the study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5364122	28337724	TS	2	contributed to the study conception and design|contributed to the acquisition of data|contributed to the analysis and interpretation of data|contributed to the critical revision	contributed to the acquisition of data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5364122	28337724	TS	2	contributed to the study conception and design|contributed to the acquisition of data|contributed to the analysis and interpretation of data|contributed to the critical revision	contributed to the analysis and interpretation of data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5364122	28337724	TS	2	contributed to the study conception and design|contributed to the acquisition of data|contributed to the analysis and interpretation of data|contributed to the critical revision	contributed to the critical revision	Wrote the paper	Writing - Review & Editing	YES
5364122	28337724	YK	2	contributed to the c-11 flumazenil synthesis	contributed to the c-11 flumazenil synthesis	-	-	NO
5553785	28797246	AW	PLoS5	Proteome design and analyses|Wrote the paper	Proteome design and analyses	Conceived and designed the experiments|Analyzed the data	Formal analysis	YES
5553785	28797246	AW	PLoS5	Proteome design and analyses|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5553785	28797246	CS	PLoS5	Proteome design and analyses	Proteome design and analyses	Conceived and designed the experiments|Analyzed the data	Formal analysis	YES
5553785	28797246	JB	PLoS5	Proteome design and analyses|Genome analyses|Wrote the paper	Proteome design and analyses	Conceived and designed the experiments|Analyzed the data	Formal analysis	YES
5553785	28797246	JB	PLoS5	Proteome design and analyses|Genome analyses|Wrote the paper	Genome analyses	Analyzed the data	Formal analysis	YES
5553785	28797246	JB	PLoS5	Proteome design and analyses|Genome analyses|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5553785	28797246	JJE	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5553785	28797246	KWS	PLoS5	Proteome design and analyses	Proteome design and analyses	Conceived and designed the experiments|Analyzed the data	Formal analysis	YES
5553785	28797246	TB	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5553785	28797246	TSD	PLoS5	Proteome design and analyses	Proteome design and analyses	Conceived and designed the experiments|Analyzed the data	Formal analysis	YES
1855433	17487272	CC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1855433	17487272	CC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1855433	17487272	CC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1855433	17487272	CC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1855433	17487272	JC	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1855433	17487272	JC	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1855433	17487272	MG	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1855433	17487272	MG	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4230829	25401074	EC	2	participated in the design of the study and performed kinetic analysis	participated in the design of the study and performed kinetic analysis	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4230829	25401074	JZ	2	carried out the molecular biology studies and chemical analysis, participated in the sequence alignment and drafted the manuscript	carried out the molecular biology studies and chemical analysis, participated in the sequence alignment and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4230829	25401074	ML	2	performed statistical data treatments and interpretation of the data	performed statistical data treatments and interpretation of the data	Analyzed the data	Formal analysis	YES
4230829	25401074	PDG	2	participated in the design of the study and the coordination and helped to draft the manuscript	participated in the design of the study and the coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft	YES
5674655	29152210	JEB	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5674655	29152210	JHA	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5674655	29152210	JJR	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5674655	29152210	NV	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4412541	25919027	TK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412541	25919027	TK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412541	25919027	TK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412541	25919027	TK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412541	25919027	TK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2958879	20932294	EEN	2	was responsible for developing the concept and design of the study, data collection, statistical analysis and manuscript preparation	was responsible for developing the concept and design of the study, data collection, statistical analysis and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
2958879	20932294	JB	2	contributed with data analysis, statistical analysis, and manuscript preparation	contributed with data analysis, statistical analysis, and manuscript preparation	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
2958879	20932294	LKA	2	contributed in the design of the study, data collection, and manuscript preparation	contributed in the design of the study, data collection, and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Methodology|Resources|Writing - Original Draft	YES
2958879	20932294	MJS	2	contributed in the design of the study, data collection, and manuscript preparation	contributed in the design of the study, data collection, and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Methodology|Resources|Writing - Original Draft	YES
2958879	20932294	MLC	2	contributed in the design of the study, data collection, and manuscript preparation	contributed in the design of the study, data collection, and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Methodology|Resources|Writing - Original Draft	YES
2958879	20932294	VAP	2	contributed in the design of the study, data collection, and manuscript preparation	contributed in the design of the study, data collection, and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Methodology|Resources|Writing - Original Draft	YES
5694492	29184567	CR-N	2	collected and analyzed plant samples, obtained data on ecological factors and virus sequences, assembled the merv genome and wrote the manuscript	collected and analyzed plant samples, obtained data on ecological factors and virus sequences, assembled the merv genome and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5694492	29184567	IP	2	designed and coordinated the study, helped collecting samples, and wrote the manuscript	designed and coordinated the study, helped collecting samples, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Project administration|Writing - Original Draft	YES
5694492	29184567	NM	2	collected samples, performed multiple regression analyses, and participated in drafting the manuscript	collected samples, performed multiple regression analyses, and participated in drafting the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4230830	25401067	CMH	2	designed and undertook the growth studies and conceived and drafted the manuscript	designed and undertook the growth studies and conceived and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Writing - Original Draft	YES
4230830	25401067	DEK	2	participated in the design of the study and written work	participated in the design of the study and written work	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4230830	25401067	EJL	2	carried out the sugar assays	carried out the sugar assays	Performed the experiments	Investigation	YES
4230830	25401067	ISD	2	participated in the design of the study and written work	participated in the design of the study and written work	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4230830	25401067	SLK	2	conceived the study, and participated in its design and coordination and helped to draft the manuscript	conceived the study, and participated in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
5364125	28337723	JT	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5364125	28337723	JT	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5364125	28337723	JT	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5364125	28337723	JT	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5364125	28337723	KH	PLoS52	contributed the reagents/materials/analysis tools	contributed the reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5364125	28337723	KIshibashi	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5364125	28337723	KIshii	PLoS52	conceived and designed the experiments|contributed the reagents/materials/analysis tools	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5364125	28337723	KIshii	PLoS52	conceived and designed the experiments|contributed the reagents/materials/analysis tools	contributed the reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5364125	28337723	KIshiwata	PLoS52	conceived and designed the experiments|performed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5364125	28337723	KIshiwata	PLoS52	conceived and designed the experiments|performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5364125	28337723	KW	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5364125	28337723	KW	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5364125	28337723	MI	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5364125	28337723	MI	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5364125	28337723	MS	PLoS52	analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5364125	28337723	MS	PLoS52	analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5553868	28797245	CA	2	supported the analysis of the klassert dataset	supported the analysis of the klassert dataset	Analyzed the data	Formal analysis	YES
5553868	28797245	DR	2	generated the saraiva microarray dataset	generated the saraiva microarray dataset	Performed the experiments	Investigation	YES
5553868	28797245	HS	2	supported the analysis of the klassert dataset	supported the analysis of the klassert dataset	Analyzed the data	Formal analysis	YES
5553868	28797245	JL	2	supported the analysis of the czakai dataset	supported the analysis of the czakai dataset	Analyzed the data	Formal analysis	YES
5553868	28797245	JPS	2	conceived and designed the study|performed all bioinformatics analysis|wrote the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5553868	28797245	JPS	2	conceived and designed the study|performed all bioinformatics analysis|wrote the manuscript	performed all bioinformatics analysis	Performed the experiments	Formal analysis|Investigation	YES
5553868	28797245	JPS	2	conceived and designed the study|performed all bioinformatics analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5553868	28797245	KC	2	supported the analysis of the czakai dataset	supported the analysis of the czakai dataset	Analyzed the data	Formal analysis	YES
5553868	28797245	MB	2	generated the saraiva microarray dataset	generated the saraiva microarray dataset	Performed the experiments	Investigation	YES
5553868	28797245	MO	2	developed and implemented the milp models	developed and implemented the milp models	Performed the experiments	Investigation|Methodology	YES
5553868	28797245	RC	2	generated the saraiva microarray dataset	generated the saraiva microarray dataset	Performed the experiments	Investigation	YES
5553868	28797245	RK	2	conceived and designed the study|developed and implemented the milp models|wrote the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5553868	28797245	RK	2	conceived and designed the study|developed and implemented the milp models|wrote the manuscript	developed and implemented the milp models	Performed the experiments	Investigation|Methodology	YES
5553868	28797245	RK	2	conceived and designed the study|developed and implemented the milp models|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5553868	28797245	TK	2	supported the analysis of the klassert dataset	supported the analysis of the klassert dataset	Analyzed the data	Formal analysis	YES
2973848	20955601	AP	7	molecular biology assays	molecular biology assays	Performed the experiments	Investigation	YES
2973848	20955601	CC	7	dissertation guidance, interpretation of the data and preparation of experimental chow	dissertation guidance, interpretation of the data and preparation of experimental chow	Analyzed the data	Formal analysis|Supervision	YES
2973848	20955601	DR	7	animal training assistance	animal training assistance	-	-	NO
2973848	20955601	FA	7	animal training assistance	animal training assistance	-	-	NO
2973848	20955601	JP	7	randomization of the protocol training of animals, literature review and elisa assays assistance	randomization of the protocol training of animals, literature review and elisa assays assistance	Conceived and designed the experiments|Performed the experiments	Formal analysis|Investigation|Methodology	YES
2973848	20955601	RV	7	molecular biology assays	molecular biology assays	Performed the experiments	Investigation	YES
1855434	17487273	AB	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1855434	17487273	AB	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1855434	17487273	LL	PLoS5	Analyzed the data|Principal investigator	Analyzed the data	Analyzed the data	Formal analysis	YES
1855434	17487273	LL	PLoS5	Analyzed the data|Principal investigator	Principal investigator	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
1855434	17487273	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1855434	17487273	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1855434	17487273	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1855434	17487273	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412563	25919745	GH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412563	25919745	GH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412563	25919745	GH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412563	25919745	KU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412563	25919745	KU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412563	25919745	KU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412563	25919745	KU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412563	25919745	KU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412563	25919745	LB	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412563	25919745	LB	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4412563	25919745	MH	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412563	25919745	MH	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412563	25919745	MP	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412563	25919745	MP	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412563	25919745	MP	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412563	25919745	MP	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412563	25919745	NH	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412563	25919745	NH	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4412563	25919745	RB	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5674656	29152211	BH	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5674656	29152211	HND	PLoS52	performed the experiments|analyzed data	performed the experiments	Performed the experiments	Investigation	YES
5674656	29152211	HND	PLoS52	performed the experiments|analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5674656	29152211	JEB	PLoS52	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5674656	29152211	JHA	PLoS52	analyzed data|wrote the manuscript	analyzed data	Analyzed the data	Formal analysis	YES
5674656	29152211	JHA	PLoS52	analyzed data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5674656	29152211	JJR	PLoS52	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5674656	29152211	NV	PLoS52	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4478977	25908603	Both authors	2	contributed equally to this study	contributed equally to this study	-	-	NO
5694493	29184559	The author	2	confirms being the sole contributor of this work and approved it for publication	confirms being the sole contributor of this work and approved it for publication	-	-	NO
2978121	20977701	CCY	2	assisted the study design and was responsible for conducting the study, including subject recruitment, skill test and data analysis	assisted the study design and was responsible for conducting the study, including subject recruitment, skill test and data analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
2978121	20977701	CKC	2	was responsible for statistical analysis and manuscript preparation	was responsible for statistical analysis and manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
2978121	20977701	CLW	2	designed the study and assisted the manuscript preparation	designed the study and assisted the manuscript preparation	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
2978121	20977701	MCS	2	carried out blood analysis and assisted the manuscript preparation	carried out blood analysis and assisted the manuscript preparation	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
2978121	20977701	MHH	2	assisted the design of the study and manuscript preparation	assisted the design of the study and manuscript preparation	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5674657	29152212	All authors	2	have significant contributions in the formulation of study design and gathering of related literature, significant contributions in writing and editing the manuscript as well as approval of the final draft, and significant contribution in the analysis and interpretation of data	have significant contributions in the formulation of study design and gathering of related literature, significant contributions in writing and editing the manuscript as well as approval of the final draft, and significant contribution in the analysis and interpretation of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5371538	28357787	AT	2	handled the data acquisition|handled the analysis of the data|handled the drafting of the manuscript	handled the data acquisition	Performed the experiments	Investigation	YES
5371538	28357787	AT	2	handled the data acquisition|handled the analysis of the data|handled the drafting of the manuscript	handled the analysis of the data	Analyzed the data	Formal analysis	YES
5371538	28357787	AT	2	handled the data acquisition|handled the analysis of the data|handled the drafting of the manuscript	handled the drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
5371538	28357787	LEE	2	handled the recruitment of the patients|handled the drafting of the manuscript	handled the recruitment of the patients	Performed the experiments	Investigation	YES
5371538	28357787	LEE	2	handled the recruitment of the patients|handled the drafting of the manuscript	handled the drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
5371538	28357787	MK	2	handled the conception and design of the study|handled the data acquisition|handled the drafting of the manuscript	handled the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5371538	28357787	MK	2	handled the conception and design of the study|handled the data acquisition|handled the drafting of the manuscript	handled the data acquisition	Performed the experiments	Investigation	YES
5371538	28357787	MK	2	handled the conception and design of the study|handled the data acquisition|handled the drafting of the manuscript	handled the drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
5371538	28357787	OG	2	handled the conception and design of the study|handled the recruitment of the patients|handled the drafting of the manuscript	handled the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5371538	28357787	OG	2	handled the conception and design of the study|handled the recruitment of the patients|handled the drafting of the manuscript	handled the recruitment of the patients	Performed the experiments	Investigation	YES
5371538	28357787	OG	2	handled the conception and design of the study|handled the recruitment of the patients|handled the drafting of the manuscript	handled the drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
5371538	28357787	RA	2	handled the conception and design of the study|handled the analysis of the data|handled the drafting of the manuscript|supervised the pilot study	handled the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5371538	28357787	RA	2	handled the conception and design of the study|handled the analysis of the data|handled the drafting of the manuscript|supervised the pilot study	handled the analysis of the data	Analyzed the data	Formal analysis	YES
5371538	28357787	RA	2	handled the conception and design of the study|handled the analysis of the data|handled the drafting of the manuscript|supervised the pilot study	handled the drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
5371538	28357787	RA	2	handled the conception and design of the study|handled the analysis of the data|handled the drafting of the manuscript|supervised the pilot study	supervised the pilot study	-	Supervision	YES
5371538	28357787	RG	2	handled the recruitment of the patients|handled the drafting of the manuscript	handled the recruitment of the patients	Performed the experiments	Investigation	YES
5371538	28357787	RG	2	handled the recruitment of the patients|handled the drafting of the manuscript	handled the drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
4230895	25401071	NY	2	participated in the design, coordination of the study and contributed in the drafting of the manuscript	participated in the design, coordination of the study and contributed in the drafting of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft	YES
1855435	17487274	AL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1855435	17487274	AL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1855435	17487274	GG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1855435	17487274	GG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1855435	17487274	GG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1855435	17487274	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1855435	17487274	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1855435	17487274	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1855435	17487274	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1855435	17487274	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1855435	17487274	MB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1855435	17487274	MB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1855435	17487274	MB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1855435	17487274	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1855435	17487274	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1855435	17487274	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1855435	17487274	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1855435	17487274	PC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1855435	17487274	PC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1855435	17487274	WB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1855435	17487274	WB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2978122	20979623	BB	2	assisted in data collection and coordinated the study	assisted in data collection and coordinated the study	Performed the experiments	Investigation|Project administration	YES
2978122	20979623	BC	2	consulted on study design, manuscript review and preparation	consulted on study design, manuscript review and preparation	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft|Writing - Review & Editing	YES
2978122	20979623	CF	2	consulted on study design, manuscript review and preparation	consulted on study design, manuscript review and preparation	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft|Writing - Review & Editing	YES
2978122	20979623	CP	2	assisted in data collection and coordinated the study|analyzed data & wrote the manuscript	assisted in data collection and coordinated the study	Performed the experiments	Investigation|Project administration	YES
2978122	20979623	CP	2	assisted in data collection and coordinated the study|analyzed data & wrote the manuscript	analyzed data & wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
2978122	20979623	CW	2	is the principal investigator|analyzed data & wrote the manuscript	is the principal investigator	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
2978122	20979623	CW	2	is the principal investigator|analyzed data & wrote the manuscript	analyzed data & wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
2978122	20979623	DW	2	analyzed blood variables	analyzed blood variables	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
2978122	20979623	LT	2	analyzed data & wrote the manuscript|analyzed blood variables|consulted on study design, manuscript review and preparation	analyzed data & wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
2978122	20979623	LT	2	analyzed data & wrote the manuscript|analyzed blood variables|consulted on study design, manuscript review and preparation	analyzed blood variables	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
2978122	20979623	LT	2	analyzed data & wrote the manuscript|analyzed blood variables|consulted on study design, manuscript review and preparation	consulted on study design, manuscript review and preparation	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft|Writing - Review & Editing	YES
2978122	20979623	RK	2	assisted in the grant preparation and securing grant funding	assisted in the grant preparation and securing grant funding	-	Funding acquisition	YES
5674658	29152213	DXF	2	was responsible for its revision	was responsible for its revision	Wrote the paper	Writing - Review & Editing	YES
5674658	29152213	GC	2	were responsible for its drafting and revision	were responsible for its drafting and revision	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5674658	29152213	RTM	2	were responsible for writing the manuscript	were responsible for writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5674658	29152213	ZQC	2	were responsible for writing the manuscript	were responsible for writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5674658	29152213	ZW	2	were responsible for its drafting and revision	were responsible for its drafting and revision	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
555549	15755320	CJG	2	conceived of the study, participated in its design, coordinated the research and analysis, and drafted the manuscript	conceived of the study, participated in its design, coordinated the research and analysis, and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
555549	15755320	DG	2	of target transcript and fragment molecules shown in figure 8, at hybridization temperatures commonly used for long oligomer arrays	of target transcript and fragment molecules shown in figure 8, at hybridization temperatures commonly used for long oligomer arrays	Performed the experiments	Investigation|Visualization	YES
555549	15755320	JWW	2	participated in the design of the study and helped to draft the manuscript	participated in the design of the study and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
555549	15755320	VGR	2	participated in the design of the study, carried out the simulations and analysis, and drafted the manuscript	participated in the design of the study, carried out the simulations and analysis, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5694494	29184568	LM-S	2	designed and wrote the manuscript	designed and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
5694494	29184568	SP	2	designed and wrote the manuscript	designed and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
4230896	25401072	JS	2	performed the mass spectrometry measurements	performed the mass spectrometry measurements	Performed the experiments	Investigation	YES
4230896	25401072	MB	2	performed the mass spectrometry measurements	performed the mass spectrometry measurements	Performed the experiments	Investigation	YES
4230896	25401072	MJ	2	carried out the flow cytometry measurements, analysed the datasets and corrected the manuscript	carried out the flow cytometry measurements, analysed the datasets and corrected the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
4230896	25401072	RT	2	conceived the study and corrected the manuscript	conceived the study and corrected the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
4230896	25401072	SL	2	carried out the chemostat cultivations, analysed the datasets and drafted the manuscript	carried out the chemostat cultivations, analysed the datasets and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4230896	25401072	SM	2	conceived the study and corrected the manuscript	conceived the study and corrected the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
4412567	25919866	AWR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412567	25919866	AWR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412567	25919866	AWR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412567	25919866	AWR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412567	25919866	AWR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412567	25919866	CSJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412567	25919866	CSJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412567	25919866	CSJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412567	25919866	CSJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412567	25919866	DLT	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412567	25919866	ETHF	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412567	25919866	GJS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412567	25919866	HZ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412567	25919866	HZ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412567	25919866	HZ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412567	25919866	HZ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412567	25919866	JLM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412567	25919866	JTB	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4412567	25919866	JTB	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412567	25919866	LA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412567	25919866	LA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412567	25919866	LA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412567	25919866	LA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412567	25919866	LA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412567	25919866	LJS	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412567	25919866	SES	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412567	25919866	SES	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412567	25919866	SES	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412567	25919866	SES	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412567	25919866	SES	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1855983	17487275	BB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1855983	17487275	BB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1855983	17487275	BB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1855983	17487275	BB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1855983	17487275	BB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5374086	28361349	BE	2	did the data gathering, formal analysis and investigation	did the data gathering, formal analysis and investigation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5374086	28361349	CL	2	contributed to the conceptualization|did the data gathering, formal analysis and investigation|did the methodology and the writing of the manuscript	contributed to the conceptualization	Conceived and designed the experiments	Conceptualization	YES
5374086	28361349	CL	2	contributed to the conceptualization|did the data gathering, formal analysis and investigation|did the methodology and the writing of the manuscript	did the data gathering, formal analysis and investigation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5374086	28361349	CL	2	contributed to the conceptualization|did the data gathering, formal analysis and investigation|did the methodology and the writing of the manuscript	did the methodology and the writing of the manuscript	Performed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5374086	28361349	HP	2	contributed to the conceptualization|did the data gathering, formal analysis and investigation	contributed to the conceptualization	Conceived and designed the experiments	Conceptualization	YES
5374086	28361349	HP	2	contributed to the conceptualization|did the data gathering, formal analysis and investigation	did the data gathering, formal analysis and investigation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5374086	28361349	NA	2	contributed to the conceptualization|did the data gathering, formal analysis and investigation|did the methodology and the writing of the manuscript|is responsible for the supervision	contributed to the conceptualization	Conceived and designed the experiments	Conceptualization	YES
5374086	28361349	NA	2	contributed to the conceptualization|did the data gathering, formal analysis and investigation|did the methodology and the writing of the manuscript|is responsible for the supervision	did the data gathering, formal analysis and investigation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5374086	28361349	NA	2	contributed to the conceptualization|did the data gathering, formal analysis and investigation|did the methodology and the writing of the manuscript|is responsible for the supervision	did the methodology and the writing of the manuscript	Performed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5374086	28361349	NA	2	contributed to the conceptualization|did the data gathering, formal analysis and investigation|did the methodology and the writing of the manuscript|is responsible for the supervision	is responsible for the supervision	-	Supervision	YES
5674659	29152214	FY	2	conceived the concept of the manuscript|drafted the paper	conceived the concept of the manuscript	Conceived and designed the experiments	Conceptualization	YES
5674659	29152214	FY	2	conceived the concept of the manuscript|drafted the paper	drafted the paper	Wrote the paper	Writing - Original Draft	YES
5674659	29152214	ZYZ	2	conceived the concept of the manuscript|revised the manuscript	conceived the concept of the manuscript	Conceived and designed the experiments	Conceptualization	YES
5674659	29152214	ZYZ	2	conceived the concept of the manuscript|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
2984406	20979659	EG	2	was responsible for data collection, input and analysis as well as manuscript preparation	was responsible for data collection, input and analysis as well as manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
2984406	20979659	PJ	2	was responsible for study design, data collection, statistical analysis, and manuscript preparation	was responsible for study design, data collection, statistical analysis, and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5556342	28807002	DPA	PLoS52	developed the methodology|carried out data generation, testing, validations and analyses|wrote the paper	developed the methodology	Performed the experiments	Methodology	YES
5556342	28807002	DPA	PLoS52	developed the methodology|carried out data generation, testing, validations and analyses|wrote the paper	carried out data generation, testing, validations and analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Validation	YES
5556342	28807002	DPA	PLoS52	developed the methodology|carried out data generation, testing, validations and analyses|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5556342	28807002	IEH	PLoS52	carried out data generation, testing, validations and analyses|wrote the paper	carried out data generation, testing, validations and analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Validation	YES
5556342	28807002	IEH	PLoS52	carried out data generation, testing, validations and analyses|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5556342	28807002	JMS	PLoS52	conceived the project|wrote the paper	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5556342	28807002	JMS	PLoS52	conceived the project|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5556342	28807002	KLJ	PLoS52	developed the methodology	developed the methodology	Performed the experiments	Methodology	YES
5694496	29184558	AA-L	2	collected and analyzed data	collected and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5694496	29184558	AK	2	conceived the experiment, generated data and wrote the manuscript	conceived the experiment, generated data and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
5694496	29184558	AM-Q	2	collected and analyzed data	collected and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5694496	29184558	DK	2	conceived the experiment, generated data and wrote the manuscript	conceived the experiment, generated data and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
5694496	29184558	DL	2	generated, analyzed data and wrote the manuscript	generated, analyzed data and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5694496	29184558	GM	2	analyzed data and wrote the manuscript	analyzed data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5694496	29184558	HvB	2	analyzed data and wrote the manuscript	analyzed data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5694496	29184558	JM	2	conceived the experiment, analyzed data and wrote the manuscript	conceived the experiment, analyzed data and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
5694496	29184558	JR	2	analyzed data and wrote the manuscript	analyzed data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5694496	29184558	LP	2	conceived the experiment, analyzed data	conceived the experiment, analyzed data	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
5694496	29184558	NH	2	analyzed data and wrote the manuscript	analyzed data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5694496	29184558	WP-M	2	conceived the experiment, analyzed data and wrote the manuscript	conceived the experiment, analyzed data and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
4230897	25401080	JDK	2	contributed equally in the design of the study|performed the experimental work and wrote the manuscript	contributed equally in the design of the study	Conceived and designed the experiments	Methodology	YES
4230897	25401080	JDK	2	contributed equally in the design of the study|performed the experimental work and wrote the manuscript	performed the experimental work and wrote the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4230897	25401080	MC	2	contributed equally in the design of the study|helped in drafting the manuscript	contributed equally in the design of the study	Conceived and designed the experiments	Methodology	YES
4230897	25401080	MC	2	contributed equally in the design of the study|helped in drafting the manuscript	helped in drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
4230897	25401080	MGG	2	contributed equally in the design of the study|helped in drafting the manuscript	contributed equally in the design of the study	Conceived and designed the experiments	Methodology	YES
4230897	25401080	MGG	2	contributed equally in the design of the study|helped in drafting the manuscript	helped in drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
2992039	21059194	All authors	2	discussed results and helped to write the discussion and conclusion	discussed results and helped to write the discussion and conclusion	Wrote the paper	-	YES
2992039	21059194	ECC	2	conducted the research, collected and tabulated data	conducted the research, collected and tabulated data	Performed the experiments	Investigation	YES
2992039	21059194	FGR	2	conducted the research, collected and tabulated data	conducted the research, collected and tabulated data	Performed the experiments	Investigation	YES
2992039	21059194	FSL	2	conducted the research, collected and tabulated data	conducted the research, collected and tabulated data	Performed the experiments	Investigation	YES
2992039	21059194	RANP	2	organized the diets	organized the diets	-	-	NO
5674660	29152215	ALW	2	designed the outline, wrote the article, and solved queries related to scientific publications from the journals	designed the outline, wrote the article, and solved queries related to scientific publications from the journals	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
5674660	29152215	JG	2	performed literature searches, critiqued the literature findings, and wrote the article	performed literature searches, critiqued the literature findings, and wrote the article	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5674660	29152215	NLS	2	designed, organized, and wrote the article	designed, organized, and wrote the article	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
5674660	29152215	SAK	2	applied clinical concepts, revised the article to add logical reasoning, and cross-checked the referencing	applied clinical concepts, revised the article to add logical reasoning, and cross-checked the referencing	Conceived and designed the experiments|Wrote the paper	Conceptualization|Validation|Writing - Review & Editing	YES
5674660	29152215	SV	2	critiqued and applied logical reasoning to the literature findings	critiqued and applied logical reasoning to the literature findings	-	-	NO
4412568	25919124	JHZ	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4412568	25919124	JHZ	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412568	25919124	KFW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412568	25919124	KFW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412568	25919124	KFW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412568	25919124	KFW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412568	25919124	LL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4412568	25919124	LL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412568	25919124	MC	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412568	25919124	MZ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412568	25919124	MZ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412568	25919124	MZ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412568	25919124	QG	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412568	25919124	QQZ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412568	25919124	TL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412568	25919124	TL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412568	25919124	TL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2994790	21067611	AP	2	initiated the study, contributed to devising the tests, interpretation of the results and drafted the manuscript|supervised the study	initiated the study, contributed to devising the tests, interpretation of the results and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
2994790	21067611	AP	2	initiated the study, contributed to devising the tests, interpretation of the results and drafted the manuscript|supervised the study	supervised the study	-	Supervision	YES
2994790	21067611	DPN	2	contributed to the study design, devising the information leaflet on nitrate and drafted the section on functional food|supervised the study	contributed to the study design, devising the information leaflet on nitrate and drafted the section on functional food	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
2994790	21067611	DPN	2	contributed to the study design, devising the information leaflet on nitrate and drafted the section on functional food|supervised the study	supervised the study	-	Supervision	YES
2994790	21067611	RJ	2	was the primary investigator and was responsible for recruitment, data collection and statistical analysis, contributed to drafting the manuscript	was the primary investigator and was responsible for recruitment, data collection and statistical analysis, contributed to drafting the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4230898	25401077	GG	2	participated in the experimental design and contributed in the drafting of the manuscript	participated in the experimental design and contributed in the drafting of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
4230898	25401077	MS	2	participated in the design and performance of the experiments and drafted the manuscript	participated in the design and performance of the experiments and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
4230898	25401077	RH	2	carried out the experiments and analysed the data	carried out the experiments and analysed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4230898	25401077	RM	2	conceived of the study, participated in its design and contributed in the drafting of the manuscript	conceived of the study, participated in its design and contributed in the drafting of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
1855984	17487276	DK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1855984	17487276	GF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1855984	17487276	GF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1855984	17487276	GF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1855984	17487276	IC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1855984	17487276	SB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1855984	17487276	TA	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1855984	17487276	UB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1855984	17487276	UB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1855984	17487276	UB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1855984	17487276	UB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1855984	17487276	WK	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5378566	28374288	AG	2	took part in the conception, design and funding of the study	took part in the conception, design and funding of the study	Conceived and designed the experiments	Conceptualization|Funding acquisition|Methodology	YES
5378566	28374288	DDB	2	performed the molecular modelling experiments	performed the molecular modelling experiments	Performed the experiments	Investigation|Methodology	YES
5378566	28374288	ERF	2	planned and performed the synthesis, radiosynthesis and preclinical experiments and wrote the manuscript	planned and performed the synthesis, radiosynthesis and preclinical experiments and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
5378566	28374288	FDV	2	performed the in vitro assays	performed the in vitro assays	Performed the experiments	Investigation	YES
5378566	28374288	SF	2	performed the in vitro assays	performed the in vitro assays	Performed the experiments	Investigation	YES
5378566	28374288	SL	2	took part in the conception, design and funding of the study	took part in the conception, design and funding of the study	Conceived and designed the experiments	Conceptualization|Funding acquisition|Methodology	YES
5694497	29184560	AR	1	Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5694497	29184560	ASF	1	Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5694497	29184560	AT	1	Conceived and designed experiments|Wrote the manuscript	Conceived and designed experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5694497	29184560	AT	1	Conceived and designed experiments|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5694497	29184560	DS	1	Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5694497	29184560	HX	1	Conceived and designed experiments	Conceived and designed experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5694497	29184560	IB	1	Conceived and designed experiments|Conducted experiments	Conceived and designed experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5694497	29184560	IB	1	Conceived and designed experiments|Conducted experiments	Conducted experiments	Performed the experiments	Investigation	YES
5694497	29184560	JD	1	Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5694497	29184560	JdSF	1	Conceived and designed experiments|Conducted experiments|Wrote the manuscript	Conceived and designed experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5694497	29184560	JdSF	1	Conceived and designed experiments|Conducted experiments|Wrote the manuscript	Conducted experiments	Performed the experiments	Investigation	YES
5694497	29184560	JdSF	1	Conceived and designed experiments|Conducted experiments|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5556373	28806913	AB	2	conceived the study and designed the experiments	conceived the study and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5556373	28806913	All authors	2	were involved in the writing of the manuscript	were involved in the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5556373	28806913	BS	2	assisted in data analysis	assisted in data analysis	Analyzed the data	Formal analysis	YES
5556373	28806913	DAM	2	performed the de novo assembly of the transcriptomes and assisted in data analysis	performed the de novo assembly of the transcriptomes and assisted in data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5556373	28806913	JWW	2	performed the experiments and analysed the data|conceived the study and designed the experiments	performed the experiments and analysed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5556373	28806913	JWW	2	performed the experiments and analysed the data|conceived the study and designed the experiments	conceived the study and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5556373	28806913	KF	2	assisted in data analysis	assisted in data analysis	Analyzed the data	Formal analysis	YES
5556373	28806913	LM	2	performed the experiments and analysed the data	performed the experiments and analysed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5556373	28806913	MT	2	assisted in data analysis	assisted in data analysis	Analyzed the data	Formal analysis	YES
5556373	28806913	WPM	2	conceived the study and designed the experiments	conceived the study and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
3009695	21156078	AG	2	were co-authors, assisting with data collection and data analysis	were co-authors, assisting with data collection and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3009695	21156078	JRH	2	was the primary investigator, designed study, supervised all study recruitment, data/specimen analysis, statistical analysis and manuscript preparation	was the primary investigator, designed study, supervised all study recruitment, data/specimen analysis, statistical analysis and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Supervision|Writing - Original Draft	YES
3009695	21156078	MO	2	contributed to the conception and design of the study	contributed to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3009695	21156078	MP	2	contributed to the conception and design of the study	contributed to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3009695	21156078	MWH	2	were co-authors, assisting with data collection and data analysis	were co-authors, assisting with data collection and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3009695	21156078	NAB	2	were co-authors, assisting with data collection and data analysis	were co-authors, assisting with data collection and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3009695	21156078	NAR	2	was a co-authors, oversaw all aspects of study including recruitment, data/specimen analysis, and manuscript preparation	was a co-authors, oversaw all aspects of study including recruitment, data/specimen analysis, and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Supervision|Writing - Original Draft	YES
3009695	21156078	RJ	2	contributed to the conception and design of the study|helped drafting the drafting the manuscript	contributed to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3009695	21156078	RJ	2	contributed to the conception and design of the study|helped drafting the drafting the manuscript	helped drafting the drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
5674661	29152216	CHH	2	searched and reviewed the literatures	searched and reviewed the literatures	-	Formal analysis	YES
5674661	29152216	PXZ	2	searched and reviewed the literatures	searched and reviewed the literatures	-	Formal analysis	YES
5674661	29152216	WWL	2	designed this study and drafted the paper	designed this study and drafted the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4412570	25919462	HY	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Sample collection	Analyzed the data	Analyzed the data	Formal analysis	YES
4412570	25919462	HY	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Sample collection	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412570	25919462	HY	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Sample collection	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412570	25919462	HY	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Sample collection	Sample collection	Performed the experiments	Investigation	YES
4412570	25919462	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Sample collection	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412570	25919462	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Sample collection	Performed the experiments	Performed the experiments	Investigation	YES
4412570	25919462	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Sample collection	Analyzed the data	Analyzed the data	Formal analysis	YES
4412570	25919462	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Sample collection	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412570	25919462	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Sample collection	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412570	25919462	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Sample collection	Sample collection	Performed the experiments	Investigation	YES
4412570	25919462	KK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Sample collection	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412570	25919462	KK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Sample collection	Performed the experiments	Performed the experiments	Investigation	YES
4412570	25919462	KK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Sample collection	Analyzed the data	Analyzed the data	Formal analysis	YES
4412570	25919462	KK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Sample collection	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412570	25919462	KK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Sample collection	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412570	25919462	KK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Sample collection	Sample collection	Performed the experiments	Investigation	YES
4412570	25919462	MA	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Sample collection	Analyzed the data	Analyzed the data	Formal analysis	YES
4412570	25919462	MA	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Sample collection	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412570	25919462	MA	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Sample collection	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412570	25919462	MA	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Sample collection	Sample collection	Performed the experiments	Investigation	YES
4412570	25919462	TI	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Sample collection	Analyzed the data	Analyzed the data	Formal analysis	YES
4412570	25919462	TI	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Sample collection	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412570	25919462	TI	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Sample collection	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412570	25919462	TI	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Sample collection	Sample collection	Performed the experiments	Investigation	YES
4412570	25919462	TS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Sample collection	Analyzed the data	Analyzed the data	Formal analysis	YES
4412570	25919462	TS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Sample collection	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412570	25919462	TS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Sample collection	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412570	25919462	TS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Sample collection	Sample collection	Performed the experiments	Investigation	YES
4412570	25919462	TY	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Sample collection	Analyzed the data	Analyzed the data	Formal analysis	YES
4412570	25919462	TY	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Sample collection	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412570	25919462	TY	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Sample collection	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412570	25919462	TY	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Sample collection	Sample collection	Performed the experiments	Investigation	YES
4412570	25919462	YT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Sample collection	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412570	25919462	YT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Sample collection	Analyzed the data	Analyzed the data	Formal analysis	YES
4412570	25919462	YT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Sample collection	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412570	25919462	YT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Sample collection	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412570	25919462	YT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Sample collection	Sample collection	Performed the experiments	Investigation	YES
4230899	25401076	AM	2	designed the study and helped to draft the manuscript	designed the study and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4230899	25401076	HT	2	conceived and designed the study, and helped to draft the manuscript	conceived and designed the study, and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
4230899	25401076	MN	2	participated in the design of the study and the kinetics analysis, and helped to draft the manuscript	participated in the design of the study and the kinetics analysis, and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4230899	25401076	MT	2	participated in the kinetics analysis of paldh	participated in the kinetics analysis of paldh	-	-	NO
4230899	25401076	NF	2	designed the study, carried out most of the biochemical studies and drafted the manuscript	designed the study, carried out most of the biochemical studies and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
1855985	17487277	AL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1855985	17487277	AL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1855985	17487277	AL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1855985	17487277	AL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1855985	17487277	AL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1855985	17487277	BS	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1855985	17487277	BS	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1855985	17487277	BS	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1855985	17487277	DP	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1855985	17487277	DP	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1855985	17487277	EM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1855985	17487277	EM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1855985	17487277	EM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1855985	17487277	EM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1855985	17487277	EM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1855985	17487277	GF	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1855985	17487277	GF	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1855985	17487277	GF	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1855985	17487277	HV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1855985	17487277	HV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1855985	17487277	HV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1855985	17487277	HV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1855985	17487277	HV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1855985	17487277	IS	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1855985	17487277	IS	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1855985	17487277	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1855985	17487277	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1855985	17487277	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1855985	17487277	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1855985	17487277	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1855985	17487277	LF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1855985	17487277	LF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1855985	17487277	LF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1855985	17487277	LF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1855985	17487277	LF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1855985	17487277	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1855985	17487277	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1855985	17487277	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1855985	17487277	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1855985	17487277	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1855985	17487277	MM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1855985	17487277	MM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1855985	17487277	MM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1855985	17487277	MM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1855985	17487277	MM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1855985	17487277	MZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1855985	17487277	MZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1855985	17487277	MZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1855985	17487277	MZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1855985	17487277	MZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1855985	17487277	RW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1855985	17487277	RW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1855985	17487277	RW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1855985	17487277	RW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1855985	17487277	RW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1855985	17487277	SB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1855985	17487277	SB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1855985	17487277	SB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1855985	17487277	TM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1855985	17487277	TM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1855985	17487277	TM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1855985	17487277	TM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1855985	17487277	VR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1855985	17487277	VR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1855985	17487277	VR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1855985	17487277	VR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1855985	17487277	VR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1855985	17487277	WP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1855985	17487277	WP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1855985	17487277	WP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1855985	17487277	WP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1855985	17487277	WP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1855985	17487277	YK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1855985	17487277	YK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1855985	17487277	YK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1855985	17487277	YK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1855985	17487277	YK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5694544	29184563	AC	2	performed calcium measurements|contributed with the wrote the article with	performed calcium measurements	Performed the experiments	Investigation	YES
5694544	29184563	AC	2	performed calcium measurements|contributed with the wrote the article with	contributed with the wrote the article with	Wrote the paper	Writing - Original Draft	YES
5694544	29184563	DB	2	identified and phenotyped the mutant|performed microscopy and gene expression studies|contributed with the wrote the article with	identified and phenotyped the mutant	Performed the experiments	Investigation	YES
5694544	29184563	DB	2	identified and phenotyped the mutant|performed microscopy and gene expression studies|contributed with the wrote the article with	performed microscopy and gene expression studies	Performed the experiments	Investigation	YES
5694544	29184563	DB	2	identified and phenotyped the mutant|performed microscopy and gene expression studies|contributed with the wrote the article with	contributed with the wrote the article with	Wrote the paper	Writing - Original Draft	YES
5694544	29184563	KV	2	wrote the article with|supervised the research	wrote the article with	Wrote the paper	Writing - Original Draft	YES
5694544	29184563	KV	2	wrote the article with|supervised the research	supervised the research	-	Supervision	YES
5694544	29184563	SS	2	identified and phenotyped the mutant|performed microscopy and gene expression studies|performed calcium measurements|contributed with the wrote the article with	identified and phenotyped the mutant	Performed the experiments	Investigation	YES
5694544	29184563	SS	2	identified and phenotyped the mutant|performed microscopy and gene expression studies|performed calcium measurements|contributed with the wrote the article with	performed microscopy and gene expression studies	Performed the experiments	Investigation	YES
5694544	29184563	SS	2	identified and phenotyped the mutant|performed microscopy and gene expression studies|performed calcium measurements|contributed with the wrote the article with	performed calcium measurements	Performed the experiments	Investigation	YES
5694544	29184563	SS	2	identified and phenotyped the mutant|performed microscopy and gene expression studies|performed calcium measurements|contributed with the wrote the article with	contributed with the wrote the article with	Wrote the paper	Writing - Original Draft	YES
5557063	28810828	AM	2	performed the experiments and data analysis|prepared the draft	performed the experiments and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5557063	28810828	AM	2	performed the experiments and data analysis|prepared the draft	prepared the draft	Wrote the paper	Writing - Original Draft	YES
5557063	28810828	BPM	2	conceived the project|designed the experiments|prepared the draft|edited and finalized the manuscript	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5557063	28810828	BPM	2	conceived the project|designed the experiments|prepared the draft|edited and finalized the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5557063	28810828	BPM	2	conceived the project|designed the experiments|prepared the draft|edited and finalized the manuscript	prepared the draft	Wrote the paper	Writing - Original Draft	YES
5557063	28810828	BPM	2	conceived the project|designed the experiments|prepared the draft|edited and finalized the manuscript	edited and finalized the manuscript	Wrote the paper	Writing - Review & Editing	YES
5557063	28810828	GKP	2	performed the experiments and data analysis	performed the experiments and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5557063	28810828	NRN	2	designed the experiments|edited and finalized the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5557063	28810828	NRN	2	designed the experiments|edited and finalized the manuscript	edited and finalized the manuscript	Wrote the paper	Writing - Review & Editing	YES
5557063	28810828	SM	2	conceived the project|designed the experiments|edited and finalized the manuscript	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5557063	28810828	SM	2	conceived the project|designed the experiments|edited and finalized the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5557063	28810828	SM	2	conceived the project|designed the experiments|edited and finalized the manuscript	edited and finalized the manuscript	Wrote the paper	Writing - Review & Editing	YES
3016253	21162744	JH	2	worked at the study site, was involved in subject recruitment, data collection and editing of the manuscript	worked at the study site, was involved in subject recruitment, data collection and editing of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
3016253	21162744	RL	2	developed the workout routine for the protocol	developed the workout routine for the protocol	Conceived and designed the experiments	Methodology	YES
3016253	21162744	SS	2	was the primary author of the manuscript	was the primary author of the manuscript	Wrote the paper	Writing - Original Draft	YES
5380646	28378292	BCA	2	enhanced the intellectual content of and reviewed the manuscript	enhanced the intellectual content of and reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5380646	28378292	HL	2	acquired and analyzed data	acquired and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5380646	28378292	HWL	2	acquired and analyzed data	acquired and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5380646	28378292	JL	2	enhanced the intellectual content of and reviewed the manuscript	enhanced the intellectual content of and reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5380646	28378292	S.B.L.	2	acquired and analyzed data and drafted the manuscript	acquired and analyzed data and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5380646	28378292	SWL	2	enhanced the intellectual content of and reviewed the manuscript	enhanced the intellectual content of and reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5380646	28378292	SYJ	2	conceptualized and designed the study, analyzed data, revised the manuscript, and approved the final content of the manuscript	conceptualized and designed the study, analyzed data, revised the manuscript, and approved the final content of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Review & Editing	YES
5380646	28378292	YHJ	2	acquired and analyzed data|enhanced the intellectual content of and reviewed the manuscript	acquired and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5380646	28378292	YHJ	2	acquired and analyzed data|enhanced the intellectual content of and reviewed the manuscript	enhanced the intellectual content of and reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5806442	29497482	DJB	7	Co-supervisor, study design, article editing	Co-supervisor, study design, article editing	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Review & Editing	YES
5806442	29497482	HCG	7	Co-supervisor, data analysis, study design, article editing	Co-supervisor, data analysis, study design, article editing	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Supervision|Writing - Review & Editing	YES
5806442	29497482	OC	7	Assisted in experiments and data analysis	Assisted in experiments and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5806442	29497482	PDC	7	Primary experimental researcher & data analyser, article author. VS and E	Primary experimental researcher & data analyser, article author. VS and E	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5806442	29497482	SAA	7	Assisted in experiments and initial design	Assisted in experiments and initial design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4230900	25401065	GW	PLoS52	conceived and designed the experiments|contributed reagents/materials/analysis tools|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4230900	25401065	GW	PLoS52	conceived and designed the experiments|contributed reagents/materials/analysis tools|wrote the paper	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4230900	25401065	GW	PLoS52	conceived and designed the experiments|contributed reagents/materials/analysis tools|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4230900	25401065	LL	PLoS52	performed the experiments|analyzed the data|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
4230900	25401065	LL	PLoS52	performed the experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
4230900	25401065	LL	PLoS52	performed the experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4230900	25401065	PS	PLoS52	conceived and designed the experiments|analyzed the data|contributed reagents/materials/analysis tools|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4230900	25401065	PS	PLoS52	conceived and designed the experiments|analyzed the data|contributed reagents/materials/analysis tools|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
4230900	25401065	PS	PLoS52	conceived and designed the experiments|analyzed the data|contributed reagents/materials/analysis tools|wrote the paper	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4230900	25401065	PS	PLoS52	conceived and designed the experiments|analyzed the data|contributed reagents/materials/analysis tools|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4230900	25401065	SQP	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4230900	25401065	YL	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
3017021	21156069	AY	2	contributed to study design and manuscript preparation	contributed to study design and manuscript preparation	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3017021	21156069	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
3017021	21156069	HL	2	contributed to study design and manuscript preparation	contributed to study design and manuscript preparation	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3017021	21156069	JK	2	participated in data collection, statistical analysis, and manuscript preparation	participated in data collection, statistical analysis, and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3017021	21156069	JM	2	served as the principal investigator and contributed to study design, data collection, and manuscript preparation	served as the principal investigator and contributed to study design, data collection, and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Funding acquisition|Investigation|Methodology|Resources|Writing - Original Draft	YES
3017021	21156069	JR	2	participated in data collection and study management	participated in data collection and study management	Performed the experiments	Investigation	YES
3017021	21156069	KW	2	participated in data collection and study management	participated in data collection and study management	Performed the experiments	Investigation	YES
3017021	21156069	NA	2	participated in data collection, statistical analysis, and manuscript preparation	participated in data collection, statistical analysis, and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3017021	21156069	SC	2	participated in data collection and study management	participated in data collection and study management	Performed the experiments	Investigation	YES
4412571	25919284	SCB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412571	25919284	SCB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4412571	25919284	SCB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4412571	25919284	SM	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4412571	25919284	SM	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4412571	25919284	SVB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412571	25919284	SVB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412571	25919284	SVB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412571	25919284	SVB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412571	25919284	TESD	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412571	25919284	TESD	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412571	25919284	TESD	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5806443	29497483	CHH	2	conducted the experiment	conducted the experiment	Performed the experiments	Investigation	YES
5806443	29497483	JJX	2	provided advice on the experiment	provided advice on the experiment	-	-	NO
5806443	29497483	PXZ	2	conducted the experiment	conducted the experiment	Performed the experiments	Investigation	YES
5806443	29497483	RPL	2	provided advice on the experiment	provided advice on the experiment	-	-	NO
5806443	29497483	WGX	2	provided advice on the experiment	provided advice on the experiment	-	-	NO
5806443	29497483	WWL	2	designed this study and drafted the paper	designed this study and drafted the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4230901	25401063	Each author	2	has participated sufficiently in the work to take public responsibility for appropriate portions of the content	has participated sufficiently in the work to take public responsibility for appropriate portions of the content	-	-	NO
4230901	25401063	LY	2	has made substantial contributions to conception and design, or acquisition of data, or analysis and interpretation of data	has made substantial contributions to conception and design, or acquisition of data, or analysis and interpretation of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
4230901	25401063	ML	2	has been involved in discussing the results conducted and drafting the manuscript and revising it critically for important intellectual content	has been involved in discussing the results conducted and drafting the manuscript and revising it critically for important intellectual content	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5383912	28389883	CMF	PLoS52	designed the research|performed the in vivo and ex vivo experiments	designed the research	Conceived and designed the experiments	Methodology	YES
5383912	28389883	CMF	PLoS52	designed the research|performed the in vivo and ex vivo experiments	performed the in vivo and ex vivo experiments	Performed the experiments	Investigation	YES
5383912	28389883	DS	PLoS52	wrote software|analysed the images	wrote software	Contributed reagents/materials/analysis tools|Wrote the paper	Software|Writing - Original Draft	YES
5383912	28389883	DS	PLoS52	wrote software|analysed the images	analysed the images	Analyzed the data	Visualization	YES
5383912	28389883	EJ	PLoS52	designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
5383912	28389883	JH	PLoS52	wrote software|analysed the images|analysed the ex vivo data|wrote the paper	wrote software	Contributed reagents/materials/analysis tools|Wrote the paper	Software|Writing - Original Draft	YES
5383912	28389883	JH	PLoS52	wrote software|analysed the images|analysed the ex vivo data|wrote the paper	analysed the images	Analyzed the data	Visualization	YES
5383912	28389883	JH	PLoS52	wrote software|analysed the images|analysed the ex vivo data|wrote the paper	analysed the ex vivo data	Analyzed the data	Formal analysis	YES
5383912	28389883	JH	PLoS52	wrote software|analysed the images|analysed the ex vivo data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5383912	28389883	JKS	PLoS52	conducted the radiochemistry work	conducted the radiochemistry work	Performed the experiments	Investigation	YES
5383912	28389883	RP	PLoS52	analysed the images	analysed the images	Analyzed the data	Visualization	YES
5383912	28389883	SJM	PLoS52	designed the research|conducted the radiochemistry work	designed the research	Conceived and designed the experiments	Methodology	YES
5383912	28389883	SJM	PLoS52	designed the research|conducted the radiochemistry work	conducted the radiochemistry work	Performed the experiments	Investigation	YES
5383912	28389883	SM	PLoS52	performed the in vivo and ex vivo experiments|analysed the ex vivo data|performed statistical analyses|wrote the paper	performed the in vivo and ex vivo experiments	Performed the experiments	Investigation	YES
5383912	28389883	SM	PLoS52	performed the in vivo and ex vivo experiments|analysed the ex vivo data|performed statistical analyses|wrote the paper	analysed the ex vivo data	Analyzed the data	Formal analysis	YES
5383912	28389883	SM	PLoS52	performed the in vivo and ex vivo experiments|analysed the ex vivo data|performed statistical analyses|wrote the paper	performed statistical analyses	Analyzed the data	Formal analysis	YES
5383912	28389883	SM	PLoS52	performed the in vivo and ex vivo experiments|analysed the ex vivo data|performed statistical analyses|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5694548	29184569	AB	2	conceived the work and wrote the manuscript|contributed to the discussion of data	conceived the work and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5694548	29184569	AB	2	conceived the work and wrote the manuscript|contributed to the discussion of data	contributed to the discussion of data	Contributed reagents/materials/analysis tools	Resources	YES
5694548	29184569	AM	2	contributed the experimental data|contributed to the discussion of data	contributed the experimental data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5694548	29184569	AM	2	contributed the experimental data|contributed to the discussion of data	contributed to the discussion of data	Contributed reagents/materials/analysis tools	Resources	YES
5694548	29184569	AP	2	contributed the experimental data|performed bioinformatic analyses|contributed to the discussion of data	contributed the experimental data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5694548	29184569	AP	2	contributed the experimental data|performed bioinformatic analyses|contributed to the discussion of data	performed bioinformatic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5694548	29184569	AP	2	contributed the experimental data|performed bioinformatic analyses|contributed to the discussion of data	contributed to the discussion of data	Contributed reagents/materials/analysis tools	Resources	YES
5694548	29184569	All authors	2	read and agreed with the final version of the manuscript	read and agreed with the final version of the manuscript	-	-	NO
5694548	29184569	PL	2	contributed the experimental data|contributed to the discussion of data	contributed the experimental data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5694548	29184569	PL	2	contributed the experimental data|contributed to the discussion of data	contributed to the discussion of data	Contributed reagents/materials/analysis tools	Resources	YES
5694548	29184569	SA	2	conceived the work and wrote the manuscript|contributed to the discussion of data	conceived the work and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5694548	29184569	SA	2	conceived the work and wrote the manuscript|contributed to the discussion of data	contributed to the discussion of data	Contributed reagents/materials/analysis tools	Resources	YES
5557070	28806931	CW	CRediT	Extraction, purification and library preparation	Extraction, purification and library preparation	Performed the experiments	Investigation	YES
5557070	28806931	MH	CRediT	Methodology|Writing - review & editing|Funding acquisition	Methodology	Performed the experiments	Methodology	YES
5557070	28806931	MH	CRediT	Methodology|Writing - review & editing|Funding acquisition	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
5557070	28806931	MH	CRediT	Methodology|Writing - review & editing|Funding acquisition	Funding acquisition	-	Funding acquisition	YES
5557070	28806931	MS	CRediT	Methodology	Methodology	Performed the experiments	Methodology	YES
5557070	28806931	RA	CRediT	Methodology|Generation|Analysis|Tables|Data compilation and assembly|Resources|Data curation|Writing - original draft|Writing - review & editing|Visualization|Funding acquisition	Methodology	Performed the experiments	Methodology	YES
5557070	28806931	RA	CRediT	Methodology|Generation|Analysis|Tables|Data compilation and assembly|Resources|Data curation|Writing - original draft|Writing - review & editing|Visualization|Funding acquisition	Generation	-	-	NO
5557070	28806931	RA	CRediT	Methodology|Generation|Analysis|Tables|Data compilation and assembly|Resources|Data curation|Writing - original draft|Writing - review & editing|Visualization|Funding acquisition	Analysis	-	-	NO
5557070	28806931	RA	CRediT	Methodology|Generation|Analysis|Tables|Data compilation and assembly|Resources|Data curation|Writing - original draft|Writing - review & editing|Visualization|Funding acquisition	Tables	-	-	NO
5557070	28806931	RA	CRediT	Methodology|Generation|Analysis|Tables|Data compilation and assembly|Resources|Data curation|Writing - original draft|Writing - review & editing|Visualization|Funding acquisition	Data compilation and assembly	-	-	NO
5557070	28806931	RA	CRediT	Methodology|Generation|Analysis|Tables|Data compilation and assembly|Resources|Data curation|Writing - original draft|Writing - review & editing|Visualization|Funding acquisition	Resources	Contributed reagents/materials/analysis tools	Resources	YES
5557070	28806931	RA	CRediT	Methodology|Generation|Analysis|Tables|Data compilation and assembly|Resources|Data curation|Writing - original draft|Writing - review & editing|Visualization|Funding acquisition	Data curation	Analyzed the data	Data curation	YES
5557070	28806931	RA	CRediT	Methodology|Generation|Analysis|Tables|Data compilation and assembly|Resources|Data curation|Writing - original draft|Writing - review & editing|Visualization|Funding acquisition	Writing - original draft	Wrote the paper	Writing - Original Draft	YES
5557070	28806931	RA	CRediT	Methodology|Generation|Analysis|Tables|Data compilation and assembly|Resources|Data curation|Writing - original draft|Writing - review & editing|Visualization|Funding acquisition	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
5557070	28806931	RA	CRediT	Methodology|Generation|Analysis|Tables|Data compilation and assembly|Resources|Data curation|Writing - original draft|Writing - review & editing|Visualization|Funding acquisition	Visualization	Analyzed the data	Visualization	YES
5557070	28806931	RA	CRediT	Methodology|Generation|Analysis|Tables|Data compilation and assembly|Resources|Data curation|Writing - original draft|Writing - review & editing|Visualization|Funding acquisition	Funding acquisition	-	Funding acquisition	YES
5557070	28806931	RP	CRediT	Methodology|Generation|Analysis|Tables|Writing - review & editing|Visualization|Funding acquisition	Methodology	Performed the experiments	Methodology	YES
5557070	28806931	RP	CRediT	Methodology|Generation|Analysis|Tables|Writing - review & editing|Visualization|Funding acquisition	Generation	-	-	NO
5557070	28806931	RP	CRediT	Methodology|Generation|Analysis|Tables|Writing - review & editing|Visualization|Funding acquisition	Analysis	-	-	NO
5557070	28806931	RP	CRediT	Methodology|Generation|Analysis|Tables|Writing - review & editing|Visualization|Funding acquisition	Tables	-	-	NO
5557070	28806931	RP	CRediT	Methodology|Generation|Analysis|Tables|Writing - review & editing|Visualization|Funding acquisition	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
5557070	28806931	RP	CRediT	Methodology|Generation|Analysis|Tables|Writing - review & editing|Visualization|Funding acquisition	Visualization	Analyzed the data	Visualization	YES
5557070	28806931	RP	CRediT	Methodology|Generation|Analysis|Tables|Writing - review & editing|Visualization|Funding acquisition	Funding acquisition	-	Funding acquisition	YES
1855986	17487278	CP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1855986	17487278	JR	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1855986	17487278	JR	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1855986	17487278	JR	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1855986	17487278	LR	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1855986	17487278	LR	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1855986	17487278	MM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1855986	17487278	MM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1855986	17487278	MM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1855986	17487278	MM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1855986	17487278	MM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1855986	17487278	OP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1855986	17487278	PO	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1855986	17487278	PO	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1855986	17487278	SF	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5806444	29497484	A Modir	2	contributed to the conception or design	contributed to the conception or design	Conceived and designed the experiments	Conceptualization	YES
5806444	29497484	A Mohammadbeigi	2	contributed to the conception or design of the work analysis, or interpretation of data for the work	contributed to the conception or design of the work analysis, or interpretation of data for the work	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Resources	YES
5806444	29497484	BY	2	contributed to the acquisition and analysis of data for the work and drafted the article	contributed to the acquisition and analysis of data for the work and drafted the article	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft	YES
5806444	29497484	EM	2	was responsible for the conception or design of the work	was responsible for the conception or design of the work	Conceived and designed the experiments	Conceptualization	YES
5806444	29497484	HM	2	contributed to the conception or design of the interpretation of data for the work	contributed to the conception or design of the interpretation of data for the work	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Resources	YES
3042913	21294857	AA	2	were responsible for the data collection|were responsible for the statistical analysis	were responsible for the data collection	Performed the experiments	Investigation	YES
3042913	21294857	AA	2	were responsible for the data collection|were responsible for the statistical analysis	were responsible for the statistical analysis	Analyzed the data	Formal analysis	YES
3042913	21294857	AH	2	were responsible for the data collection|were responsible for the statistical analysis	were responsible for the data collection	Performed the experiments	Investigation	YES
3042913	21294857	AH	2	were responsible for the data collection|were responsible for the statistical analysis	were responsible for the statistical analysis	Analyzed the data	Formal analysis	YES
3042913	21294857	All authors	2	reviewed and contributed to the final manuscript	reviewed and contributed to the final manuscript	Wrote the paper	Writing - Review & Editing	YES
3042913	21294857	TV	2	were responsible for the data collection	were responsible for the data collection	Performed the experiments	Investigation	YES
4412572	25919295	AY	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4412572	25919295	AY	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4412572	25919295	DCM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412572	25919295	DCM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412572	25919295	DCM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412572	25919295	DCM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412572	25919295	EP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412572	25919295	EP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412572	25919295	EP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412572	25919295	EP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412572	25919295	EZ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412572	25919295	EZ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412572	25919295	EZ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412572	25919295	KFF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412572	25919295	KFF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412572	25919295	KFF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412572	25919295	KFF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412572	25919295	RD	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412572	25919295	RD	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412572	25919295	RD	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5389953	28405927	All authors	2	contributed to the conceptualizing and drafting of the manuscript	contributed to the conceptualizing and drafting of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
3824810	24282376	All the authors	2	including declare that they participated in the study concept and design|have seen and approved the final version of the paper	including declare that they participated in the study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
3824810	24282376	All the authors	2	including declare that they participated in the study concept and design|have seen and approved the final version of the paper	have seen and approved the final version of the paper	-	-	NO
3824810	24282376	Jingbing Wang	2	were two primary operators in this interventional treatment|contributed in this paper revision and is the cocorresponding writer	were two primary operators in this interventional treatment	Performed the experiments	Investigation	YES
3824810	24282376	Jingbing Wang	2	were two primary operators in this interventional treatment|contributed in this paper revision and is the cocorresponding writer	contributed in this paper revision and is the cocorresponding writer	Wrote the paper	Writing - Review & Editing	YES
3824810	24282376	Ke Li	2	participated in its coordination and helped to draft the paper	participated in its coordination and helped to draft the paper	Wrote the paper	Project administration|Writing - Original Draft	YES
3824810	24282376	Xiao An	2	were two primary operators in this interventional treatment|wrote the study report and drafted the paper	were two primary operators in this interventional treatment	Performed the experiments	Investigation	YES
3824810	24282376	Xiao An	2	were two primary operators in this interventional treatment|wrote the study report and drafted the paper	wrote the study report and drafted the paper	Wrote the paper	Writing - Original Draft	YES
5694554	29184565	AJ	2	assisted in the writing and interpretation of the data	assisted in the writing and interpretation of the data	Analyzed the data|Wrote the paper	Formal analysis	YES
5694554	29184565	All authors	2	were involved in the planning and design of the study, edited and approved the final manuscript	were involved in the planning and design of the study, edited and approved the final manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5694554	29184565	IA	2	assisted in the writing and interpretation of the data	assisted in the writing and interpretation of the data	Analyzed the data|Wrote the paper	Formal analysis	YES
5694554	29184565	JDJ	2	were responsible for the field experiments and phenotyping in the field	were responsible for the field experiments and phenotyping in the field	Performed the experiments	Investigation	YES
5694554	29184565	JO	2	assisted in the writing and interpretation of the data	assisted in the writing and interpretation of the data	Analyzed the data|Wrote the paper	Formal analysis	YES
5694554	29184565	LK	2	were responsible for the field experiments and phenotyping in the field	were responsible for the field experiments and phenotyping in the field	Performed the experiments	Investigation	YES
5694554	29184565	LR	2	were responsible for the field experiments and phenotyping in the field	were responsible for the field experiments and phenotyping in the field	Performed the experiments	Investigation	YES
5694554	29184565	OM	2	assisted in the writing and interpretation of the data	assisted in the writing and interpretation of the data	Analyzed the data|Wrote the paper	Formal analysis	YES
5694554	29184565	SSRs	2	the mlo evaluation	the mlo evaluation	-	-	NO
5694554	29184565	TB	2	performed the gwas and statistical analysis, wrote the manuscript, made the figures and finalized the tables	performed the gwas and statistical analysis, wrote the manuscript, made the figures and finalized the tables	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Visualization|Writing - Original Draft	YES
5694554	29184565	TC	2	were responsible for the field experiments and phenotyping in the field	were responsible for the field experiments and phenotyping in the field	Performed the experiments	Investigation	YES
1855987	17487279	FR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1855987	17487279	FR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1855987	17487279	FR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1855987	17487279	FR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1855987	17487279	HR	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1855987	17487279	HR	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1855987	17487279	KH	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1855987	17487279	KH	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1855987	17487279	PO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1855987	17487279	PO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1855987	17487279	PO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1855987	17487279	PO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4892130	27335626	AEJ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
4892130	27335626	AK	PLoS52	performed the experiments|analyzed the data|critically revised the manuscript	performed the experiments	Performed the experiments	Investigation	YES
4892130	27335626	AK	PLoS52	performed the experiments|analyzed the data|critically revised the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
4892130	27335626	AK	PLoS52	performed the experiments|analyzed the data|critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4892130	27335626	All authors	PLoS52	gave final approval of the article to be published and agree to be accountable for all aspects of the work	gave final approval of the article to be published and agree to be accountable for all aspects of the work	-	-	NO
4892130	27335626	LLG	PLoS52	designed the study|performed the experiments|analyzed the data|wrote the manuscript|critically revised the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
4892130	27335626	LLG	PLoS52	designed the study|performed the experiments|analyzed the data|wrote the manuscript|critically revised the manuscript	performed the experiments	Performed the experiments	Investigation	YES
4892130	27335626	LLG	PLoS52	designed the study|performed the experiments|analyzed the data|wrote the manuscript|critically revised the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
4892130	27335626	LLG	PLoS52	designed the study|performed the experiments|analyzed the data|wrote the manuscript|critically revised the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4892130	27335626	LLG	PLoS52	designed the study|performed the experiments|analyzed the data|wrote the manuscript|critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4892130	27335626	MI	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
4892130	27335626	QLM	PLoS52	designed the study|analyzed the data|wrote the manuscript|critically revised the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
4892130	27335626	QLM	PLoS52	designed the study|analyzed the data|wrote the manuscript|critically revised the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
4892130	27335626	QLM	PLoS52	designed the study|analyzed the data|wrote the manuscript|critically revised the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4892130	27335626	QLM	PLoS52	designed the study|analyzed the data|wrote the manuscript|critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4892130	27335626	VK	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
3049131	21324203	BC	2	participated in protocol design, data analyses and manuscript preparation	participated in protocol design, data analyses and manuscript preparation	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3049131	21324203	CJC	2	participated in protocol design, conduct of the study, data analyses and manuscript preparation	participated in protocol design, conduct of the study, data analyses and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
3049131	21324203	CMG	2	participated in protocol design, data analyses and manuscript preparation	participated in protocol design, data analyses and manuscript preparation	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3049131	21324203	LPK	2	participated in protocol design, data analyses and manuscript preparation	participated in protocol design, data analyses and manuscript preparation	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3049131	21324203	SD	2	participated in protocol design, data analyses and manuscript preparation	participated in protocol design, data analyses and manuscript preparation	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5557254	28806970	BL	PLoS52	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5557254	28806970	CA	PLoS52	carried out the experiments|analysed the data|wrote the manuscript, with input from all authors	carried out the experiments	Performed the experiments	Investigation	YES
5557254	28806970	CA	PLoS52	carried out the experiments|analysed the data|wrote the manuscript, with input from all authors	analysed the data	Analyzed the data	Formal analysis	YES
5557254	28806970	CA	PLoS52	carried out the experiments|analysed the data|wrote the manuscript, with input from all authors	wrote the manuscript, with input from all authors	Wrote the paper	Writing - Original Draft	YES
5557254	28806970	CAM	PLoS52	carried out the experiments|analysed the data	carried out the experiments	Performed the experiments	Investigation	YES
5557254	28806970	CAM	PLoS52	carried out the experiments|analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
5557254	28806970	DCH	PLoS52	carried out the experiments|analysed the data	carried out the experiments	Performed the experiments	Investigation	YES
5557254	28806970	DCH	PLoS52	carried out the experiments|analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
5557254	28806970	DGB	PLoS52	carried out the experiments|wrote the manuscript, with input from all authors	carried out the experiments	Performed the experiments	Investigation	YES
5557254	28806970	DGB	PLoS52	carried out the experiments|wrote the manuscript, with input from all authors	wrote the manuscript, with input from all authors	Wrote the paper	Writing - Original Draft	YES
5557254	28806970	DJM	PLoS52	wrote the manuscript, with input from all authors	wrote the manuscript, with input from all authors	Wrote the paper	Writing - Original Draft	YES
5557254	28806970	J-BR	PLoS52	carried out the experiments|analysed the data|wrote the manuscript, with input from all authors	carried out the experiments	Performed the experiments	Investigation	YES
5557254	28806970	J-BR	PLoS52	carried out the experiments|analysed the data|wrote the manuscript, with input from all authors	analysed the data	Analyzed the data	Formal analysis	YES
5557254	28806970	J-BR	PLoS52	carried out the experiments|analysed the data|wrote the manuscript, with input from all authors	wrote the manuscript, with input from all authors	Wrote the paper	Writing - Original Draft	YES
5557254	28806970	SF	PLoS52	analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
5399011	28429332	All authors	2	drafted and edited the article and approved the final manuscript	drafted and edited the article and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5399011	28429332	EL	2	conceived of and made the study design|carried out the data analysis and interpretation|participated in the collection and assembly of the data	conceived of and made the study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5399011	28429332	EL	2	conceived of and made the study design|carried out the data analysis and interpretation|participated in the collection and assembly of the data	carried out the data analysis and interpretation	Analyzed the data	Formal analysis	YES
5399011	28429332	EL	2	conceived of and made the study design|carried out the data analysis and interpretation|participated in the collection and assembly of the data	participated in the collection and assembly of the data	Performed the experiments	Investigation	YES
5399011	28429332	GC	2	conceived of and made the study design|carried out the data analysis and interpretation|participated in the collection and assembly of the data	conceived of and made the study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5399011	28429332	GC	2	conceived of and made the study design|carried out the data analysis and interpretation|participated in the collection and assembly of the data	carried out the data analysis and interpretation	Analyzed the data	Formal analysis	YES
5399011	28429332	GC	2	conceived of and made the study design|carried out the data analysis and interpretation|participated in the collection and assembly of the data	participated in the collection and assembly of the data	Performed the experiments	Investigation	YES
5399011	28429332	MS	2	carried out the data analysis and interpretation|participated in the collection and assembly of the data	carried out the data analysis and interpretation	Analyzed the data	Formal analysis	YES
5399011	28429332	MS	2	carried out the data analysis and interpretation|participated in the collection and assembly of the data	participated in the collection and assembly of the data	Performed the experiments	Investigation	YES
5399011	28429332	RF	2	conceived of and made the study design|participated in the collection and assembly of the data	conceived of and made the study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5399011	28429332	RF	2	conceived of and made the study design|participated in the collection and assembly of the data	participated in the collection and assembly of the data	Performed the experiments	Investigation	YES
5399011	28429332	VG	2	carried out the data analysis and interpretation|participated in the collection and assembly of the data	carried out the data analysis and interpretation	Analyzed the data	Formal analysis	YES
5399011	28429332	VG	2	carried out the data analysis and interpretation|participated in the collection and assembly of the data	participated in the collection and assembly of the data	Performed the experiments	Investigation	YES
5399011	28429332	VW	2	conceived of and made the study design|carried out the data analysis and interpretation|participated in the collection and assembly of the data	conceived of and made the study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5399011	28429332	VW	2	conceived of and made the study design|carried out the data analysis and interpretation|participated in the collection and assembly of the data	carried out the data analysis and interpretation	Analyzed the data	Formal analysis	YES
5399011	28429332	VW	2	conceived of and made the study design|carried out the data analysis and interpretation|participated in the collection and assembly of the data	participated in the collection and assembly of the data	Performed the experiments	Investigation	YES
4412573	25918999	DWD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412573	25918999	DWD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412573	25918999	DWD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412573	25918999	DWD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412573	25918999	KML	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412573	25918999	KML	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412573	25918999	KML	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412573	25918999	KML	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412573	25918999	MP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412573	25918999	MP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412573	25918999	MP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3063821	21362194	AJN	2	is the principal investigator of the project|designed the study|conducted data analysis|wrote the manuscript	is the principal investigator of the project	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
3063821	21362194	AJN	2	is the principal investigator of the project|designed the study|conducted data analysis|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
3063821	21362194	AJN	2	is the principal investigator of the project|designed the study|conducted data analysis|wrote the manuscript	conducted data analysis	Analyzed the data	Formal analysis	YES
3063821	21362194	AJN	2	is the principal investigator of the project|designed the study|conducted data analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3063821	21362194	All authors	2	have read and approved the final manuscript	have read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
3063821	21362194	FSCF	2	designed the study|collected the data|conducted data analysis|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
3063821	21362194	FSCF	2	designed the study|collected the data|conducted data analysis|wrote the manuscript	collected the data	Performed the experiments	Investigation	YES
3063821	21362194	FSCF	2	designed the study|collected the data|conducted data analysis|wrote the manuscript	conducted data analysis	Analyzed the data	Formal analysis	YES
3063821	21362194	FSCF	2	designed the study|collected the data|conducted data analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3063821	21362194	MACJ	2	collected the data	collected the data	Performed the experiments	Investigation	YES
3063821	21362194	NMBC	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
3063821	21362194	SAF	2	collected the data	collected the data	Performed the experiments	Investigation	YES
1855988	17502916	KK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1855988	17502916	KK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1855988	17502916	KK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1855988	17502916	KK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1855988	17502916	KK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5806445	29497485	ATS	PLoS52	performed the experiments|analyzed the data|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5806445	29497485	ATS	PLoS52	performed the experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5806445	29497485	ATS	PLoS52	performed the experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5806445	29497485	HH	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5806445	29497485	HK	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5806445	29497485	JN	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5806445	29497485	KE	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5806445	29497485	KE	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5806445	29497485	KM	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5806445	29497485	KM	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5806445	29497485	KM	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5806445	29497485	KM	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5806445	29497485	KT	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5806445	29497485	OK	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5806445	29497485	YW	PLoS52	conceived and designed the experiments|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5806445	29497485	YW	PLoS52	conceived and designed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4230905	25401070	EV	1	Acquisition of data, analysis and interpretation of data	Acquisition of data, analysis and interpretation of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5806446	29497486	GF	2	read the manuscript	read the manuscript	-	-	NO
5806446	29497486	IK	2	conceived the study, created the data, and wrote the manuscript	conceived the study, created the data, and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5806446	29497486	JM	2	developed the model	developed the model	Performed the experiments	Methodology	YES
5806446	29497486	MP	2	developed the model	developed the model	Performed the experiments	Methodology	YES
3066115	21414230	CGM	2	were responsible for data collection/entry and assistance with manuscript preparation	were responsible for data collection/entry and assistance with manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Investigation|Writing - Original Draft	YES
3066115	21414230	JFT	2	were responsible for data collection/entry and assistance with manuscript preparation	were responsible for data collection/entry and assistance with manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Investigation|Writing - Original Draft	YES
3066115	21414230	REC	2	were responsible for data collection/entry and assistance with manuscript preparation	were responsible for data collection/entry and assistance with manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Investigation|Writing - Original Draft	YES
3066115	21414230	RJB	2	was responsible for the study designs, overseeing data collection, biochemical work, statistical analysis, and preparation of the manuscript	was responsible for the study designs, overseeing data collection, biochemical work, statistical analysis, and preparation of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Supervision|Writing - Original Draft	YES
3066115	21414230	TMF	2	were responsible for data collection/entry and assistance with manuscript preparation	were responsible for data collection/entry and assistance with manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Investigation|Writing - Original Draft	YES
4412574	25919138	DFM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412574	25919138	DFM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412574	25919138	DFM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412574	25919138	DFM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412574	25919138	DFM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412574	25919138	HM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412574	25919138	HM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412574	25919138	HM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412574	25919138	HM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412574	25919138	HM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412574	25919138	WM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412574	25919138	WM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412574	25919138	WM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412574	25919138	WM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412574	25919138	WM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4231364	25405080	JS	2	participated in the expression and purification of the recombinant enzymes	participated in the expression and purification of the recombinant enzymes	Performed the experiments	Investigation	YES
4231364	25405080	JT	2	performed the molecular dynamics simulations	performed the molecular dynamics simulations	Performed the experiments	Formal analysis|Investigation	YES
4231364	25405080	MB	2	participated in the expression and purification of the recombinant enzymes	participated in the expression and purification of the recombinant enzymes	Performed the experiments	Investigation	YES
4231364	25405080	NK	2	carried out the recombinant cloning of genes coding for the polyester hydrolases	carried out the recombinant cloning of genes coding for the polyester hydrolases	Performed the experiments	Investigation	YES
4231364	25405080	RW	2	carried out the recombinant cloning of genes coding for the polyester hydrolases|carried out the biochemical characterization of the polyester hydrolases|analyzed the experimental and simulation data and prepared the manuscript	carried out the recombinant cloning of genes coding for the polyester hydrolases	Performed the experiments	Investigation	YES
4231364	25405080	RW	2	carried out the recombinant cloning of genes coding for the polyester hydrolases|carried out the biochemical characterization of the polyester hydrolases|analyzed the experimental and simulation data and prepared the manuscript	carried out the biochemical characterization of the polyester hydrolases	Performed the experiments	Investigation	YES
4231364	25405080	RW	2	carried out the recombinant cloning of genes coding for the polyester hydrolases|carried out the biochemical characterization of the polyester hydrolases|analyzed the experimental and simulation data and prepared the manuscript	analyzed the experimental and simulation data and prepared the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4231364	25405080	TO	2	carried out the biochemical characterization of the polyester hydrolases|analyzed the experimental and simulation data and prepared the manuscript	carried out the biochemical characterization of the polyester hydrolases	Performed the experiments	Investigation	YES
4231364	25405080	TO	2	carried out the biochemical characterization of the polyester hydrolases|analyzed the experimental and simulation data and prepared the manuscript	analyzed the experimental and simulation data and prepared the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4231364	25405080	WZ	2	conceived the study and contributed to manuscript writing	conceived the study and contributed to manuscript writing	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5557327	28806914	HJJ	2	screened redundant sequences and analysed collinearity and expression patterns	screened redundant sequences and analysed collinearity and expression patterns	Performed the experiments	Investigation	YES
5557327	28806914	HPZ	2	contributed to the detailed experimental design and the management and interpretation of data	contributed to the detailed experimental design and the management and interpretation of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Formal analysis|Investigation|Methodology|Resources	YES
5557327	28806914	JYW	2	contributed to literature research and guided the integrity of the entire study	contributed to literature research and guided the integrity of the entire study	-	Formal analysis|Supervision	YES
5557327	28806914	LTL	2	improved the methodology for data collection and analysis	improved the methodology for data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5557327	28806914	MRF	2	contributed to the interpretation of evolution analysis	contributed to the interpretation of evolution analysis	Analyzed the data	Formal analysis	YES
5557327	28806914	SLZ	2	conceived and designed the details of the experiments and involved in revising the manuscript	conceived and designed the details of the experiments and involved in revising the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
5557327	28806914	XL	2	contributed to the data analysis and manuscript drafting	contributed to the data analysis and manuscript drafting	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5557327	28806914	XQ	2	screened redundant sequences and analysed collinearity and expression patterns	screened redundant sequences and analysed collinearity and expression patterns	Performed the experiments	Investigation	YES
1855989	17502917	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1855989	17502917	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1855989	17502917	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1855989	17502917	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1855989	17502917	AT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1855989	17502917	AT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1855989	17502917	AT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1855989	17502917	AT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1855989	17502917	AT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1855989	17502917	BS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1855989	17502917	BS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1855989	17502917	BS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1855989	17502917	BS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1855989	17502917	KT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1855989	17502917	KT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1855989	17502917	KT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1855989	17502917	MB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1855989	17502917	MB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1855989	17502917	MB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1855989	17502917	MB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1855989	17502917	MG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1855989	17502917	MG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1855989	17502917	MG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1855989	17502917	RP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1855989	17502917	RP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1855989	17502917	RP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5694560	29184557	CP	2	performed the analysis	performed the analysis	Performed the experiments	Investigation	YES
5694560	29184557	JS	2	wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
5694560	29184557	QA	2	performed the analysis	performed the analysis	Performed the experiments	Investigation	YES
5694560	29184557	UQ	2	performed the analysis|wrote the article	performed the analysis	Performed the experiments	Investigation	YES
5694560	29184557	UQ	2	performed the analysis|wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
5400775	28432674	AAL	2	contributed to the study design and data interpretation, participated in reviewing the manuscript and gave final approval of the paper	contributed to the study design and data interpretation, participated in reviewing the manuscript and gave final approval of the paper	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Review & Editing	YES
5400775	28432674	BBNvB	2	contributed to the data acquisition, participated in reviewing the manuscript and gave final approval of the paper	contributed to the data acquisition, participated in reviewing the manuscript and gave final approval of the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5400775	28432674	ML	2	contributed to the data interpretation, participated in drafting the manuscript and gave final approval of the paper	contributed to the data interpretation, participated in drafting the manuscript and gave final approval of the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5400775	28432674	RB	2	contributed to the study design, data analysis and interpretation	contributed to the study design, data analysis and interpretation	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Methodology|Resources	YES
5400775	28432674	SSVG	2	contributed to the data analysis and interpretation, participated in drafting the manuscript and gave final approval of the paper	contributed to the data analysis and interpretation, participated in drafting the manuscript and gave final approval of the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5806447	29497487	AM	7	Contributions to the conception or design of the work analysis, and interpretation of data for the work	Contributions to the conception or design of the work analysis, and interpretation of data for the work	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Resources	YES
5806447	29497487	FT	7	Contributions to the conception or design of the interpretation of data for the work	Contributions to the conception or design of the interpretation of data for the work	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Resources	YES
5806447	29497487	HAR	7	Contributions to the conception or design of the work; analysis and interpretation of data	Contributions to the conception or design of the work; analysis and interpretation of data	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Resources	YES
5806447	29497487	NJ	7	Contributions to the conception or design of the work	Contributions to the conception or design of the work	Conceived and designed the experiments	Conceptualization	YES
4412575	25919015	TS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412575	25919015	TS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412575	25919015	TS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412575	25919015	TS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5557427	28806919	All of the authors	PLoS52	reviewed and approved the manuscript	reviewed and approved the manuscript	Wrote the paper	Writing - Review & Editing	YES
5557427	28806919	CSQ	PLoS52	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5557427	28806919	LZC	PLoS52	conducted the data analysis and prepared figures and tables	conducted the data analysis and prepared figures and tables	Analyzed the data	Formal analysis|Visualization	YES
5557427	28806919	WQT	PLoS52	conducted the snp validation	conducted the snp validation	Performed the experiments	Investigation|Validation	YES
5557427	28806919	YSW	PLoS52	conceived this study, and designed and supervised the experiments	conceived this study, and designed and supervised the experiments	Conceived and designed the experiments	Conceptualization|Methodology|Supervision	YES
5557427	28806919	ZC	PLoS52	conceived this study, and designed and supervised the experiments|performed the experiments|wrote the manuscript|conducted the snp validation	conceived this study, and designed and supervised the experiments	Conceived and designed the experiments	Conceptualization|Methodology|Supervision	YES
5557427	28806919	ZC	PLoS52	conceived this study, and designed and supervised the experiments|performed the experiments|wrote the manuscript|conducted the snp validation	performed the experiments	Performed the experiments	Investigation	YES
5557427	28806919	ZC	PLoS52	conceived this study, and designed and supervised the experiments|performed the experiments|wrote the manuscript|conducted the snp validation	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5557427	28806919	ZC	PLoS52	conceived this study, and designed and supervised the experiments|performed the experiments|wrote the manuscript|conducted the snp validation	conducted the snp validation	Performed the experiments	Investigation|Validation	YES
5557427	28806919	ZGQ	PLoS52	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5557427	28806919	ZGS	PLoS52	conceived this study, and designed and supervised the experiments|performed the experiments|conducted the data analysis and prepared figures and tables|wrote the manuscript	conceived this study, and designed and supervised the experiments	Conceived and designed the experiments	Conceptualization|Methodology|Supervision	YES
5557427	28806919	ZGS	PLoS52	conceived this study, and designed and supervised the experiments|performed the experiments|conducted the data analysis and prepared figures and tables|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5557427	28806919	ZGS	PLoS52	conceived this study, and designed and supervised the experiments|performed the experiments|conducted the data analysis and prepared figures and tables|wrote the manuscript	conducted the data analysis and prepared figures and tables	Analyzed the data	Formal analysis|Visualization	YES
5557427	28806919	ZGS	PLoS52	conceived this study, and designed and supervised the experiments|performed the experiments|conducted the data analysis and prepared figures and tables|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5694649	29184564	All of the authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5694649	29184564	C-KB	2	critically read the manuscript and improved the text	critically read the manuscript and improved the text	-	-	NO
5694649	29184564	DK	2	produced the figures	produced the figures	-	Visualization	YES
5694649	29184564	RH	2	conceived the study and coordinated the work	conceived the study and coordinated the work	Conceived and designed the experiments	Conceptualization|Project administration	YES
5694649	29184564	RM	2	critically read the manuscript and improved the text	critically read the manuscript and improved the text	-	-	NO
5694649	29184564	RRM	2	conceived the study and coordinated the work	conceived the study and coordinated the work	Conceived and designed the experiments	Conceptualization|Project administration	YES
1855990	17487280	CS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1855990	17487280	CS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1855990	17487280	KB	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1855990	17487280	KB	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1855990	17487280	SE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1855990	17487280	SE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1855990	17487280	SE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1855990	17487280	SE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5403773	28439843	EP	2	participated in data collection and data analysis and prepared the manuscript	participated in data collection and data analysis and prepared the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5403773	28439843	JA	2	participated in data analysis and revision of the manuscript	participated in data analysis and revision of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5403773	28439843	JAR	2	participated in data analysis and revision of the manuscript	participated in data analysis and revision of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5403773	28439843	JMMC	2	participated in the study design, data collection, and data analysis and prepared the manuscript	participated in the study design, data collection, and data analysis and prepared the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5403773	28439843	LS	2	participated in data analysis and revision of the manuscript	participated in data analysis and revision of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5403773	28439843	MJGV	2	participated in data analysis and revision of the manuscript	participated in data analysis and revision of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5403773	28439843	MRF	2	participated in data analysis and revision of the manuscript	participated in data analysis and revision of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5403773	28439843	VM	2	participated in data collection and data analysis	participated in data collection and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4412576	25919141	CA	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412576	25919141	EL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412576	25919141	GPC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412576	25919141	JAG	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412576	25919141	JQ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412576	25919141	JQ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412576	25919141	JQ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412576	25919141	JQ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412576	25919141	LPD	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4412576	25919141	MR-M	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412576	25919141	NG-H	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412576	25919141	PM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412576	25919141	PM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412576	25919141	PM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412576	25919141	PM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412576	25919141	RA	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
3079604	21473783	BK	2	designed the study and wrote the manuscript	designed the study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3079604	21473783	CM	2	carried out blood analysis and assisted the manuscript preparation	carried out blood analysis and assisted the manuscript preparation	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3079604	21473783	OS	2	was responsible for statistical analysis and manuscript preparation	was responsible for statistical analysis and manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3079604	21473783	PB	2	assisted in data analysis, data interpretation and manuscript preparation	assisted in data analysis, data interpretation and manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3079604	21473783	PK	2	carried out blood analysis and assisted the manuscript preparation	carried out blood analysis and assisted the manuscript preparation	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3079604	21473783	RI	2	assisted in data analysis, data interpretation and manuscript preparation	assisted in data analysis, data interpretation and manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3079604	21473783	TR	2	assisted the design of the study and manuscript preparation	assisted the design of the study and manuscript preparation	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5806448	29497488	HML	2	reviewed relative articles and drafted the manuscript|provided original creative ideals	reviewed relative articles and drafted the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5806448	29497488	HML	2	reviewed relative articles and drafted the manuscript|provided original creative ideals	provided original creative ideals	Conceived and designed the experiments	Conceptualization	YES
5806448	29497488	JWG	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5806448	29497488	RFZ	2	gave some important advices after reading the draft	gave some important advices after reading the draft	Wrote the paper	Writing - Original Draft	YES
1855991	17502918	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1855991	17502918	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1855991	17502918	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1855991	17502918	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1855991	17502918	MB	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5694787	29187862	All authors	2	contributed to write and approve the manuscript	contributed to write and approve the manuscript	Wrote the paper	Writing - Original Draft	YES
5403775	28439844	All authors	2	conceived and designed the study, and all authors critically reviewed the manuscript	conceived and designed the study, and all authors critically reviewed the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
5557475	28806912	HZ	PLoS52	contributed reagents/materials/analysis tools	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5557475	28806912	JYG	PLoS52	revised the paper	revised the paper	Wrote the paper	Writing - Review & Editing	YES
5557475	28806912	LFC	PLoS52	contributed reagents/materials/analysis tools	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5557475	28806912	LSY	PLoS52	contributed reagents/materials/analysis tools	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5557475	28806912	SPY	PLoS52	conceived and designed the experiments|wrote the paper|revised the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5557475	28806912	SPY	PLoS52	conceived and designed the experiments|wrote the paper|revised the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5557475	28806912	SPY	PLoS52	conceived and designed the experiments|wrote the paper|revised the paper	revised the paper	Wrote the paper	Writing - Review & Editing	YES
5557475	28806912	TLW	PLoS52	contributed reagents/materials/analysis tools	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5557475	28806912	TTH	PLoS52	contributed reagents/materials/analysis tools	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5557475	28806912	XLD	PLoS52	contributed reagents/materials/analysis tools	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5557475	28806912	XW	PLoS52	contributed reagents/materials/analysis tools	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5557475	28806912	YWL	PLoS52	conceived and designed the experiments|performed the experiments and analyzed the data|contributed reagents/materials/analysis tools|wrote the paper|revised the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5557475	28806912	YWL	PLoS52	conceived and designed the experiments|performed the experiments and analyzed the data|contributed reagents/materials/analysis tools|wrote the paper|revised the paper	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5557475	28806912	YWL	PLoS52	conceived and designed the experiments|performed the experiments and analyzed the data|contributed reagents/materials/analysis tools|wrote the paper|revised the paper	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5557475	28806912	YWL	PLoS52	conceived and designed the experiments|performed the experiments and analyzed the data|contributed reagents/materials/analysis tools|wrote the paper|revised the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5557475	28806912	YWL	PLoS52	conceived and designed the experiments|performed the experiments and analyzed the data|contributed reagents/materials/analysis tools|wrote the paper|revised the paper	revised the paper	Wrote the paper	Writing - Review & Editing	YES
5806449	29497489	DPZ	2	were responsible for writing the manuscript	were responsible for writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5806449	29497489	GC	2	were responsible for its drafting and revision	were responsible for its drafting and revision	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5806449	29497489	HYL	2	was responsible for its revision	was responsible for its revision	Wrote the paper	Writing - Review & Editing	YES
5806449	29497489	ZW	2	were responsible for its drafting and revision	were responsible for its drafting and revision	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5806449	29497489	ZWZ	2	were responsible for writing the manuscript	were responsible for writing the manuscript	Wrote the paper	Writing - Original Draft	YES
3117768	21595961	BW	2	was involved in subject recruitment, data collection and editing the manuscript	was involved in subject recruitment, data collection and editing the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
3117768	21595961	BWF	2	helped to draft the manuscript	helped to draft the manuscript	Wrote the paper	Writing - Original Draft	YES
3117768	21595961	LW	2	was involved in subject recruitment, data collection and helped to draft the manuscript	was involved in subject recruitment, data collection and helped to draft the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3117768	21595961	LYB	2	was the primary author of the manuscript	was the primary author of the manuscript	Wrote the paper	Writing - Original Draft	YES
3117768	21595961	RR	2	was involved in subject recruitment, data collection and helped to draft the manuscript	was involved in subject recruitment, data collection and helped to draft the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3117768	21595961	YPP	2	conceived of the study, participated in its design and coordination and helped to draft the manuscript	conceived of the study, participated in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
3117768	21595961	ZB	2	was involved in subject recruitment, data collection and editing the manuscript	was involved in subject recruitment, data collection and editing the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4412578	25919116	BS	PLoS5	Gathered data and performed detailed statistical analysis of the data	Gathered data and performed detailed statistical analysis of the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4412578	25919116	DS	PLoS5	Wrote the paper|Helped write and proofread the manuscript|Performed orbit analysis of the data	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412578	25919116	DS	PLoS5	Wrote the paper|Helped write and proofread the manuscript|Performed orbit analysis of the data	Helped write and proofread the manuscript	Wrote the paper	Writing - Original Draft	YES
4412578	25919116	DS	PLoS5	Wrote the paper|Helped write and proofread the manuscript|Performed orbit analysis of the data	Performed orbit analysis of the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4412578	25919116	FC	PLoS5	Generated orbits and constructed the gui/software for orbit visualization	Generated orbits and constructed the gui/software for orbit visualization	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Investigation|Software|Visualization	YES
4412578	25919116	MVV	PLoS5	Wrote the paper|Wrote, prepared, and proofread the manuscript|Performed orbit analysis of the data	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412578	25919116	MVV	PLoS5	Wrote the paper|Wrote, prepared, and proofread the manuscript|Performed orbit analysis of the data	Wrote, prepared, and proofread the manuscript	Wrote the paper	Writing - Original Draft	YES
4412578	25919116	MVV	PLoS5	Wrote the paper|Wrote, prepared, and proofread the manuscript|Performed orbit analysis of the data	Performed orbit analysis of the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3825124	24282375	The authors	2	contributed equally to the work	contributed equally to the work	-	-	NO
1855992	17487281	JD	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1855992	17487281	JD	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1855992	17487281	LN	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1855992	17487281	LN	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1855992	17487281	OM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1855992	17487281	OM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1855992	17487281	OM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
3133534	21693050	All authors	2	contributed to the interpretation of results, critically reviewed the manuscript for intellectual content, and gave approval of the final version of the manuscript to be published	contributed to the interpretation of results, critically reviewed the manuscript for intellectual content, and gave approval of the final version of the manuscript to be published	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
3133534	21693050	EAF	2	conceived the study idea and analyzed the data|designed the study|carried out data collection, and drafted the manuscript	conceived the study idea and analyzed the data	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
3133534	21693050	EAF	2	conceived the study idea and analyzed the data|designed the study|carried out data collection, and drafted the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
3133534	21693050	EAF	2	conceived the study idea and analyzed the data|designed the study|carried out data collection, and drafted the manuscript	carried out data collection, and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3133534	21693050	EPW	2	conceived the study idea and analyzed the data|designed the study	conceived the study idea and analyzed the data	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
3133534	21693050	EPW	2	conceived the study idea and analyzed the data|designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
3133534	21693050	JLM	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5694819	29187859	HS	2	collectively wrote the manuscript and initiated the work behind it	collectively wrote the manuscript and initiated the work behind it	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5694819	29187859	NI	2	collectively wrote the manuscript and initiated the work behind it|contributed with major parts of the literature research	collectively wrote the manuscript and initiated the work behind it	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5694819	29187859	NI	2	collectively wrote the manuscript and initiated the work behind it|contributed with major parts of the literature research	contributed with major parts of the literature research	-	Formal analysis	YES
5409907	28455733	JMN	2	designed the study|worked together on statistical analysis and data interpretation|oversaw the study	designed the study	Conceived and designed the experiments	Methodology	YES
5409907	28455733	JMN	2	designed the study|worked together on statistical analysis and data interpretation|oversaw the study	worked together on statistical analysis and data interpretation	Performed the experiments|Analyzed the data	Formal analysis	YES
5409907	28455733	JMN	2	designed the study|worked together on statistical analysis and data interpretation|oversaw the study	oversaw the study	-	Supervision	YES
5409907	28455733	NG	2	designed the study|collected, anonymized and analysed all data sets|worked together on statistical analysis and data interpretation|led the write up of the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5409907	28455733	NG	2	designed the study|collected, anonymized and analysed all data sets|worked together on statistical analysis and data interpretation|led the write up of the manuscript	collected, anonymized and analysed all data sets	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5409907	28455733	NG	2	designed the study|collected, anonymized and analysed all data sets|worked together on statistical analysis and data interpretation|led the write up of the manuscript	worked together on statistical analysis and data interpretation	Performed the experiments|Analyzed the data	Formal analysis	YES
5409907	28455733	NG	2	designed the study|collected, anonymized and analysed all data sets|worked together on statistical analysis and data interpretation|led the write up of the manuscript	led the write up of the manuscript	Wrote the paper	Writing - Original Draft	YES
5409907	28455733	PET-CT	2	acquisition and analysis	acquisition and analysis	-	-	NO
5409907	28455733	PK	2	designed the study|oversaw the study	designed the study	Conceived and designed the experiments	Methodology	YES
5409907	28455733	PK	2	designed the study|oversaw the study	oversaw the study	-	Supervision	YES
5409907	28455733	SF	2	designed the study|worked together on statistical analysis and data interpretation	designed the study	Conceived and designed the experiments	Methodology	YES
5409907	28455733	SF	2	designed the study|worked together on statistical analysis and data interpretation	worked together on statistical analysis and data interpretation	Performed the experiments|Analyzed the data	Formal analysis	YES
5409907	28455733	all authors	2	contributed to revising the manuscript and all approved the final manuscript	contributed to revising the manuscript and all approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5557481	28806925	DC	2	helped to interpret the results and refine the manuscript	helped to interpret the results and refine the manuscript	Analyzed the data	Formal analysis	YES
5557481	28806925	ESM	2	carried out the data analysis|helped to interpret the results and refine the manuscript	carried out the data analysis	Analyzed the data	Formal analysis	YES
5557481	28806925	ESM	2	carried out the data analysis|helped to interpret the results and refine the manuscript	helped to interpret the results and refine the manuscript	Analyzed the data	Formal analysis	YES
5557481	28806925	JAW	2	provided helpful advice on the data analysis|helped to interpret the results and refine the manuscript	provided helpful advice on the data analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5557481	28806925	JAW	2	provided helpful advice on the data analysis|helped to interpret the results and refine the manuscript	helped to interpret the results and refine the manuscript	Analyzed the data	Formal analysis	YES
5557481	28806925	MH	2	helped to interpret the results and refine the manuscript	helped to interpret the results and refine the manuscript	Analyzed the data	Formal analysis	YES
5557481	28806925	PW	2	conceived and designed the study|carried out the data analysis|drafted the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5557481	28806925	PW	2	conceived and designed the study|carried out the data analysis|drafted the manuscript	carried out the data analysis	Analyzed the data	Formal analysis	YES
5557481	28806925	PW	2	conceived and designed the study|carried out the data analysis|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5557481	28806925	SB	2	helped to interpret the results and refine the manuscript	helped to interpret the results and refine the manuscript	Analyzed the data	Formal analysis	YES
1857822	17487282	CB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1857822	17487282	CB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1857822	17487282	CB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1857822	17487282	DR	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1857822	17487282	DR	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1857822	17487282	DR	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1857822	17487282	FR	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1857822	17487282	FR	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1857822	17487282	GT	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1857822	17487282	JC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1857822	17487282	LK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1857822	17487282	LK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1857822	17487282	LK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1857822	17487282	MB	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1857822	17487282	PB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1857822	17487282	PB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1857822	17487282	PB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1857822	17487282	SA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1857822	17487282	SA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1857822	17487282	SA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1857822	17487282	TB	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1857822	17487282	TB	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5937297	29770189	JLH	2	performed experiments and drafted the paper	performed experiments and drafted the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5937297	29770189	WWL	2	designed the experiment and revised the article	designed the experiment and revised the article	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5937297	29770189	XJS	2	designed the experiment and revised the article	designed the experiment and revised the article	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
3141631	21689421	BC	2	assisted in data collection, data analysis, and/or manuscript preparation	assisted in data collection, data analysis, and/or manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3141631	21689421	CMK	2	assisted in data collection, data analysis, and/or manuscript preparation	assisted in data collection, data analysis, and/or manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3141631	21689421	CR	2	assisted in data collection, data analysis, and/or manuscript preparation	assisted in data collection, data analysis, and/or manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3141631	21689421	CW	2	assisted in data collection and manuscript preparation	assisted in data collection and manuscript preparation	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3141631	21689421	DW	2	oversaw analysis of blood work	oversaw analysis of blood work	Performed the experiments	Investigation|Supervision	YES
3141631	21689421	EN	2	assisted in data collection, data analysis, and/or manuscript preparation	assisted in data collection, data analysis, and/or manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3141631	21689421	KD	2	assisted in data collection, data analysis, and/or manuscript preparation	assisted in data collection, data analysis, and/or manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3141631	21689421	LG	2	assisted in data collection, data analysis, and/or manuscript preparation	assisted in data collection, data analysis, and/or manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3141631	21689421	LS	2	provided input on study design and results	provided input on study design and results	Conceived and designed the experiments	Methodology	YES
3141631	21689421	MC	2	assisted in data collection, data analysis, and/or manuscript preparation	assisted in data collection, data analysis, and/or manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3141631	21689421	MF	2	assisted in data collection, data analysis, and/or manuscript preparation	assisted in data collection, data analysis, and/or manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3141631	21689421	MI	2	assisted in data collection, data analysis, and/or manuscript preparation	assisted in data collection, data analysis, and/or manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3141631	21689421	RBK	2	served as principal investigator and contributed to the design of the study, statistical analysis, manuscript preparation, and procurement of external funding	served as principal investigator and contributed to the design of the study, statistical analysis, manuscript preparation, and procurement of external funding	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Funding acquisition|Methodology|Writing - Original Draft	YES
3141631	21689421	RL	2	assisted in data collection, data analysis, and/or manuscript preparation	assisted in data collection, data analysis, and/or manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3141631	21689421	TMC	2	served as the study supervisor, oversaw all testing, and assisted in writing of the manuscript	served as the study supervisor, oversaw all testing, and assisted in writing of the manuscript	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Original Draft	YES
4412579	25919025	AT	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4412579	25919025	ES	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4412579	25919025	MS	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4412579	25919025	MY	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4412579	25919025	NK	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4412579	25919025	OY	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412579	25919025	RA	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4412579	25919025	SO	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412579	25919025	SO	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412579	25919025	SO	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412579	25919025	TC	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412579	25919025	TC	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412579	25919025	TM	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4412579	25919025	YO	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5694821	29187861	S-QP	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5694821	29187861	YW	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5340830	27220743	A. Gustafsson	2	undertook the statistical analyses|performed the literature search|wrote the first draft of the manuscript	undertook the statistical analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5340830	27220743	A. Gustafsson	2	undertook the statistical analyses|performed the literature search|wrote the first draft of the manuscript	performed the literature search	Performed the experiments	Formal analysis|Investigation	YES
5340830	27220743	A. Gustafsson	2	undertook the statistical analyses|performed the literature search|wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
5340830	27220743	All authors	2	contributed to the discussion and have approved the final manuscript	contributed to the discussion and have approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5340830	27220743	I. Rydberg	2	managed the data collection and preparation of data in accordance with the protocol|managed the mph analyses	managed the data collection and preparation of data in accordance with the protocol	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Data curation|Investigation|Methodology	YES
5340830	27220743	I. Rydberg	2	managed the data collection and preparation of data in accordance with the protocol|managed the mph analyses	managed the mph analyses	Analyzed the data	Formal analysis	YES
5340830	27220743	M. Josefsson	2	managed the mph analyses|performed the literature search	managed the mph analyses	Analyzed the data	Formal analysis	YES
5340830	27220743	M. Josefsson	2	managed the mph analyses|performed the literature search	performed the literature search	Performed the experiments	Formal analysis|Investigation	YES
5340830	27220743	O. Hollertz	2	managed the data collection and preparation of data in accordance with the protocol	managed the data collection and preparation of data in accordance with the protocol	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Data curation|Investigation|Methodology	YES
5340830	27220743	P. Woxler	2	managed the data collection and preparation of data in accordance with the protocol	managed the data collection and preparation of data in accordance with the protocol	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Data curation|Investigation|Methodology	YES
5340830	27220743	T. Trygg	2	managed the data collection and preparation of data in accordance with the protocol	managed the data collection and preparation of data in accordance with the protocol	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Data curation|Investigation|Methodology	YES
1857823	17487283	BB	PLoS5	Independent confirmation of main results	Independent confirmation of main results	-	-	NO
1857823	17487283	DD	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1857823	17487283	DD	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1857823	17487283	HM	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1857823	17487283	HM	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1857823	17487283	LC	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1857823	17487283	TK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1857823	17487283	TK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1857823	17487283	TK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1857823	17487283	WA	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1857823	17487283	YH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5937298	29770191	NM	PLoS52	participated in the design of experiments|contributed reagents and materials|carried out the experiments|analyzed the data|drafted the manuscript|corrected the final manuscript	participated in the design of experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5937298	29770191	NM	PLoS52	participated in the design of experiments|contributed reagents and materials|carried out the experiments|analyzed the data|drafted the manuscript|corrected the final manuscript	contributed reagents and materials	Contributed reagents/materials/analysis tools	Resources	YES
5937298	29770191	NM	PLoS52	participated in the design of experiments|contributed reagents and materials|carried out the experiments|analyzed the data|drafted the manuscript|corrected the final manuscript	carried out the experiments	Performed the experiments	Investigation	YES
5937298	29770191	NM	PLoS52	participated in the design of experiments|contributed reagents and materials|carried out the experiments|analyzed the data|drafted the manuscript|corrected the final manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5937298	29770191	NM	PLoS52	participated in the design of experiments|contributed reagents and materials|carried out the experiments|analyzed the data|drafted the manuscript|corrected the final manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5937298	29770191	NM	PLoS52	participated in the design of experiments|contributed reagents and materials|carried out the experiments|analyzed the data|drafted the manuscript|corrected the final manuscript	corrected the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5937298	29770191	YS	PLoS52	carried out the experiments|analyzed the data	carried out the experiments	Performed the experiments	Investigation	YES
5937298	29770191	YS	PLoS52	carried out the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5937298	29770191	YT	PLoS52	participated in the design of experiments|carried out the experiments|analyzed the data|drafted the manuscript	participated in the design of experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5937298	29770191	YT	PLoS52	participated in the design of experiments|carried out the experiments|analyzed the data|drafted the manuscript	carried out the experiments	Performed the experiments	Investigation	YES
5937298	29770191	YT	PLoS52	participated in the design of experiments|carried out the experiments|analyzed the data|drafted the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5937298	29770191	YT	PLoS52	participated in the design of experiments|carried out the experiments|analyzed the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
3142197	21722409	HK	2	designed the study and were responsible for data analysis and interpretation|contributed to screening and recruitment of participants and data collection|drafted the manuscript	designed the study and were responsible for data analysis and interpretation	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
3142197	21722409	HK	2	designed the study and were responsible for data analysis and interpretation|contributed to screening and recruitment of participants and data collection|drafted the manuscript	contributed to screening and recruitment of participants and data collection	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
3142197	21722409	HK	2	designed the study and were responsible for data analysis and interpretation|contributed to screening and recruitment of participants and data collection|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
3142197	21722409	RC	2	designed the study and were responsible for data analysis and interpretation|supervised all procedure of this study and the manuscript	designed the study and were responsible for data analysis and interpretation	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
3142197	21722409	RC	2	designed the study and were responsible for data analysis and interpretation|supervised all procedure of this study and the manuscript	supervised all procedure of this study and the manuscript	Performed the experiments	Investigation|Supervision	YES
3142197	21722409	SIGL	2	contributed to screening and recruitment of participants and data collection	contributed to screening and recruitment of participants and data collection	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4412622	25919476	AS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412622	25919476	AS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412622	25919476	AS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412622	25919476	EDA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412622	25919476	EDA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4412622	25919476	EDA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412622	25919476	IK	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4412622	25919476	IP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412622	25919476	IP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412622	25919476	IP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412622	25919476	IP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412622	25919476	IP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412622	25919476	JT	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412622	25919476	JT	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4412622	25919476	LG	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412622	25919476	LG	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4412622	25919476	SA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412622	25919476	SA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412622	25919476	SA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412622	25919476	SA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412622	25919476	VC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412622	25919476	VC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4412622	25919476	VC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5415447	28470406	AH	2	contributed to the conception and design of the study	contributed to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5415447	28470406	DD	2	participated in the acquisition of the data	participated in the acquisition of the data	Performed the experiments	Investigation	YES
5415447	28470406	DLG	2	contributed to the conception and design of the study	contributed to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5415447	28470406	DRV	2	contributed to the conception and design of the study|made the critical revision	contributed to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5415447	28470406	DRV	2	contributed to the conception and design of the study|made the critical revision	made the critical revision	Wrote the paper	Writing - Review & Editing	YES
5415447	28470406	FH	2	contributed to the conception and design of the study|participated in the acquisition of the data|carried out the analysis and interpretation of the data|made the critical revision	contributed to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5415447	28470406	FH	2	contributed to the conception and design of the study|participated in the acquisition of the data|carried out the analysis and interpretation of the data|made the critical revision	participated in the acquisition of the data	Performed the experiments	Investigation	YES
5415447	28470406	FH	2	contributed to the conception and design of the study|participated in the acquisition of the data|carried out the analysis and interpretation of the data|made the critical revision	carried out the analysis and interpretation of the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5415447	28470406	FH	2	contributed to the conception and design of the study|participated in the acquisition of the data|carried out the analysis and interpretation of the data|made the critical revision	made the critical revision	Wrote the paper	Writing - Review & Editing	YES
5415447	28470406	JEF	2	contributed to the conception and design of the study	contributed to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5415447	28470406	JV	2	participated in the acquisition of the data	participated in the acquisition of the data	Performed the experiments	Investigation	YES
5415447	28470406	KS	2	participated in the acquisition of the data|carried out the analysis and interpretation of the data	participated in the acquisition of the data	Performed the experiments	Investigation	YES
5415447	28470406	KS	2	participated in the acquisition of the data|carried out the analysis and interpretation of the data	carried out the analysis and interpretation of the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5415447	28470406	MB	2	participated in the acquisition of the data	participated in the acquisition of the data	Performed the experiments	Investigation	YES
5415447	28470406	MS	2	contributed to the conception and design of the study|made the critical revision	contributed to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5415447	28470406	MS	2	contributed to the conception and design of the study|made the critical revision	made the critical revision	Wrote the paper	Writing - Review & Editing	YES
5415447	28470406	NA	2	participated in the acquisition of the data|carried out the analysis and interpretation of the data	participated in the acquisition of the data	Performed the experiments	Investigation	YES
5415447	28470406	NA	2	participated in the acquisition of the data|carried out the analysis and interpretation of the data	carried out the analysis and interpretation of the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5415447	28470406	RAL	2	participated in the acquisition of the data	participated in the acquisition of the data	Performed the experiments	Investigation	YES
5415447	28470406	SGN	2	made the critical revision	made the critical revision	Wrote the paper	Writing - Review & Editing	YES
5415447	28470406	SM	2	participated in the acquisition of the data	participated in the acquisition of the data	Performed the experiments	Investigation	YES
5415447	28470406	YD	2	contributed to the conception and design of the study	contributed to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5415447	28470406	YL	2	participated in the acquisition of the data	participated in the acquisition of the data	Performed the experiments	Investigation	YES
5415447	28470406	ZQ	2	participated in the acquisition of the data	participated in the acquisition of the data	Performed the experiments	Investigation	YES
5415447	28470406	ZV	2	contributed to the conception and design of the study|participated in the acquisition of the data|carried out the analysis and interpretation of the data|drafted the manuscript	contributed to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5415447	28470406	ZV	2	contributed to the conception and design of the study|participated in the acquisition of the data|carried out the analysis and interpretation of the data|drafted the manuscript	participated in the acquisition of the data	Performed the experiments	Investigation	YES
5415447	28470406	ZV	2	contributed to the conception and design of the study|participated in the acquisition of the data|carried out the analysis and interpretation of the data|drafted the manuscript	carried out the analysis and interpretation of the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5415447	28470406	ZV	2	contributed to the conception and design of the study|participated in the acquisition of the data|carried out the analysis and interpretation of the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
1857824	17502919	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1857824	17502919	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1857824	17502919	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1857824	17502919	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1857824	17502919	EG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1857824	17502919	EG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1857824	17502919	EG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1857824	17502919	EG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1857824	17502919	FB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1857824	17502919	FB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1857824	17502919	FB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1857824	17502919	FB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1857824	17502919	MR	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1857824	17502919	MR	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1857824	17502919	MR	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1857824	17502919	PB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1857824	17502919	PB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1857824	17502919	PB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1857824	17502919	PB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1857824	17502919	VT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1857824	17502919	VT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1857824	17502919	VT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3161391	20836884	The author	2	of this study is solely responsible for the study design, subject recruitment and health screening, data analysis, and manuscript preparation	of this study is solely responsible for the study design, subject recruitment and health screening, data analysis, and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5694822	29187860	All authors	2	contributed to and have read and approved the final version of the manuscript	contributed to and have read and approved the final version of the manuscript	-	-	NO
5694822	29187860	IB	2	conceived the project and contributed to experimental design	conceived the project and contributed to experimental design	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
5694822	29187860	LH	2	prepared functional genotypes and performed associative transcriptomics	prepared functional genotypes and performed associative transcriptomics	Performed the experiments	Investigation	YES
5694822	29187860	MB	2	conceived the project and contributed to experimental design	conceived the project and contributed to experimental design	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
5694822	29187860	NG	2	conceived the project and contributed to experimental design|wrote the manuscript	conceived the project and contributed to experimental design	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
5694822	29187860	NG	2	conceived the project and contributed to experimental design|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5694822	29187860	PW	2	conceived the project and contributed to experimental design	conceived the project and contributed to experimental design	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
5694822	29187860	TA	2	conceived the project and contributed to experimental design|analyzed associative transcriptomics data and performed and analyzed a|wrote the manuscript	conceived the project and contributed to experimental design	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
5694822	29187860	TA	2	conceived the project and contributed to experimental design|analyzed associative transcriptomics data and performed and analyzed a|wrote the manuscript	analyzed associative transcriptomics data and performed and analyzed a	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5694822	29187860	TA	2	conceived the project and contributed to experimental design|analyzed associative transcriptomics data and performed and analyzed a|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5694822	29187860	ZH	2	prepared functional genotypes and performed associative transcriptomics	prepared functional genotypes and performed associative transcriptomics	Performed the experiments	Investigation	YES
555753	15762987	A.S.	2	provides the tissue samples and clinical information	provides the tissue samples and clinical information	Contributed reagents/materials/analysis tools	Resources	YES
555753	15762987	C.M.A.	2	is the principal investigator and was involved in the conceptualization, design and writing of the manuscript	is the principal investigator and was involved in the conceptualization, design and writing of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Funding acquisition|Writing - Original Draft	YES
555753	15762987	H.S.	2	carried out the breast cancer sage libraries and provided practical feedback on aspects of the manuscript	carried out the breast cancer sage libraries and provided practical feedback on aspects of the manuscript	Performed the experiments	Investigation	YES
555753	15762987	J.A.D.	2	carried out the breast cancer sage libraries and provided practical feedback on aspects of the manuscript	carried out the breast cancer sage libraries and provided practical feedback on aspects of the manuscript	Performed the experiments	Investigation	YES
555753	15762987	K.B.	2	developed the biostatistical and web-page base methodology	developed the biostatistical and web-page base methodology	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Methodology|Software	YES
555753	15762987	M.C.A.	2	conceived the study idea and carried out the real time rt pcr validations, the biostatistical/ bioinformatics analysis and writing the manuscript	conceived the study idea and carried out the real time rt pcr validations, the biostatistical/ bioinformatics analysis and writing the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Validation|Writing - Original Draft	YES
555753	15762987	S.G.	2	developed the biostatistical and web-page base methodology	developed the biostatistical and web-page base methodology	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Methodology|Software	YES
555753	15762987	Y.H.	2	carried out the breast cancer sage libraries and provided practical feedback on aspects of the manuscript	carried out the breast cancer sage libraries and provided practical feedback on aspects of the manuscript	Performed the experiments	Investigation	YES
3177873	21892942	AOO	2	wrote the analysis plan with input from other author and drafted the manuscript	wrote the analysis plan with input from other author and drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
3177873	21892942	Both authors	2	were involved in the implementation of the study as well as read and approved the final manuscript	were involved in the implementation of the study as well as read and approved the final manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
3177873	21892942	YO	2	conducted the analysis and participated in the interpretation of the results and provided critical comments	conducted the analysis and participated in the interpretation of the results and provided critical comments	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4412624	25919614	HH	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412624	25919614	IK	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412624	25919614	KA	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412624	25919614	MM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412624	25919614	MM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412624	25919614	MM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412624	25919614	MU	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412624	25919614	T. Ikegami	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412624	25919614	T. Ikegami	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412624	25919614	T. Ikegami	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412624	25919614	T. Ikegami	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412624	25919614	T. Inatsugi	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5937299	29770192	All the authors	2	have contributed to drafting/revising the manuscript, study concept, or design, as well as data gathering and interpretation	have contributed to drafting/revising the manuscript, study concept, or design, as well as data gathering and interpretation	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5422222	28485003	All authors	2	were responsible for the article	were responsible for the article	-	-	NO
5422222	28485003	BS	2	initiated and oversaw the project	initiated and oversaw the project	Conceived and designed the experiments	Conceptualization|Supervision	YES
5422222	28485003	KW	2	gave administrative support	gave administrative support	-	Project administration	YES
5422222	28485003	YW	2	provided help for collecting the material	provided help for collecting the material	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5422222	28485003	YX	2	provided help for collecting the material	provided help for collecting the material	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
1859837	17505532	BB	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1859837	17505532	CM	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1859837	17505532	CM	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1859837	17505532	ED	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1859837	17505532	JM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Moreno	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1859837	17505532	JM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Moreno	Analyzed the data	Analyzed the data	Formal analysis	YES
1859837	17505532	JM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Moreno	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1859837	17505532	JM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Moreno	Moreno	-	-	NO
1859837	17505532	LM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1859837	17505532	NB	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1859837	17505532	NB	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1859837	17505532	NS	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1859837	17505532	SL	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1859837	17505532	SL	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
3826291	24288489	G. Baltopoulos	2	read and approved the final version of the paper	read and approved the final version of the paper	-	-	NO
3190328	21955383	EPO	2	wrote the manuscript, revised it and approved the final version of the manuscript	wrote the manuscript, revised it and approved the final version of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3190328	21955383	RCB	2	wrote, read and approved the final version of the manuscript	wrote, read and approved the final version of the manuscript	Wrote the paper	Writing - Original Draft	YES
5694824	29187858	AD-S	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5694824	29187858	AG-G	2	designed the study|made the molecular procedures|conducted the analyses	designed the study	Conceived and designed the experiments	Methodology	YES
5694824	29187858	AG-G	2	designed the study|made the molecular procedures|conducted the analyses	made the molecular procedures	Performed the experiments	Investigation	YES
5694824	29187858	AG-G	2	designed the study|made the molecular procedures|conducted the analyses	conducted the analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5694824	29187858	AM-Y	2	conducted the analyses	conducted the analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5694824	29187858	All authors	2	revised the results and wrote the manuscript	revised the results and wrote the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5694824	29187858	DP	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5694824	29187858	MS-A	2	conducted the analyses	conducted the analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
1859838	17505533	DB	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1859838	17505533	DB	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1859838	17505533	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1859838	17505533	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1859838	17505533	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1859838	17505533	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5937300	29770193	JZ	2	was the corresponding author and participated in conceiving the manuscript	was the corresponding author and participated in conceiving the manuscript	Conceived and designed the experiments	Conceptualization	YES
5937300	29770193	WB	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
555759	15760469	AA	2	carried out the laboratory work and part of the data analysis and provided input to the manuscript	carried out the laboratory work and part of the data analysis and provided input to the manuscript	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
555759	15760469	ACS	2	initiated the study, supervised it, and coordinated the manuscript writing process	initiated the study, supervised it, and coordinated the manuscript writing process	Conceived and designed the experiments|Wrote the paper	Conceptualization|Project administration|Supervision|Writing - Original Draft	YES
555759	15760469	LL	2	planned the experiments, guided the laboratory work and performed the analysis of results, interpreted the data and drafted the manuscript	planned the experiments, guided the laboratory work and performed the analysis of results, interpreted the data and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Supervision|Writing - Original Draft	YES
3206405	21992447	KG	2	the first author designed and wrote the introduction and the conclusion	the first author designed and wrote the introduction and the conclusion	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
3206405	21992447	SH	2	participated in the design of the study and performed the statistical analysis	participated in the design of the study and performed the statistical analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5937301	29770194	Performed Medline	2	searches, aided in writing the review article and critiqued the literature	searches, aided in writing the review article and critiqued the literature	Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
1859839	17487284	BS	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1859839	17487284	BS	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1859839	17487284	DG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1859839	17487284	DL	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1859839	17487284	DL	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1859839	17487284	DS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1859839	17487284	DS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1859839	17487284	DS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1859839	17487284	JS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1859839	17487284	JS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1859839	17487284	JS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1859839	17487284	RM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1859839	17487284	RM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1859839	17487284	RM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1859839	17487284	RM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1859839	17487284	RT	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1859839	17487284	RT	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1859839	17487284	SK	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5432456	28508284	All authors	2	participated in the study planning, data analysis and drafting of the manuscript and approved the final version	participated in the study planning, data analysis and drafting of the manuscript and approved the final version	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5696338	29201033	FZ	2	helped in manuscript preparation and revision	helped in manuscript preparation and revision	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5696338	29201033	GZ	2	helped in manuscript preparation and revision	helped in manuscript preparation and revision	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5696338	29201033	LS	2	helped in manuscript preparation and revision	helped in manuscript preparation and revision	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5696338	29201033	MG	2	conducted phenotyping, data analysis and prepared the draft	conducted phenotyping, data analysis and prepared the draft	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5696338	29201033	MZ	2	conceived and supervised the project, reviewed and revised the manuscript	conceived and supervised the project, reviewed and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Supervision|Writing - Review & Editing	YES
5696338	29201033	SS	2	conceived and supervised the project, reviewed and revised the manuscript	conceived and supervised the project, reviewed and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Supervision|Writing - Review & Editing	YES
5696338	29201033	YF	2	assisted mapping, qtl analysis and candidate gene search	assisted mapping, qtl analysis and candidate gene search	-	-	NO
3210081	22017963	AB	2	assisted with statistical analysis	assisted with statistical analysis	Analyzed the data	Formal analysis	YES
3210081	22017963	AP	2	was the primary author and carried out data collection, analysis of blood samples, and statistical analysis	was the primary author and carried out data collection, analysis of blood samples, and statistical analysis	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3210081	22017963	AT	2	helped collect data	helped collect data	Performed the experiments	Investigation	YES
3210081	22017963	CR	2	assisted with analysis of blood samples	assisted with analysis of blood samples	Performed the experiments	Investigation	YES
3210081	22017963	JG	2	helped collect data	helped collect data	Performed the experiments	Investigation	YES
3210081	22017963	JL	2	assisted with analysis of poms and sst data	assisted with analysis of poms and sst data	Analyzed the data	Formal analysis	YES
3210081	22017963	JO	2	assisted with analysis of blood samples	assisted with analysis of blood samples	Performed the experiments	Investigation	YES
3210081	22017963	MB	2	assisted with analysis of poms and sst data|assisted with analysis of blood samples	assisted with analysis of poms and sst data	Analyzed the data	Formal analysis	YES
3210081	22017963	MB	2	assisted with analysis of poms and sst data|assisted with analysis of blood samples	assisted with analysis of blood samples	Performed the experiments	Investigation	YES
3210081	22017963	MG	2	assisted with manuscript preparation	assisted with manuscript preparation	Wrote the paper	Writing - Original Draft	YES
3210081	22017963	RK	2	assisted with manuscript preparation	assisted with manuscript preparation	Wrote the paper	Writing - Original Draft	YES
3210081	22017963	SS	2	assisted with analysis of blood samples	assisted with analysis of blood samples	Performed the experiments	Investigation	YES
555765	15723697	Christoph Dieterich	2	built the entire pipeline and some parts of the web interface	built the entire pipeline and some parts of the web interface	Contributed reagents/materials/analysis tools	Software	YES
555765	15723697	Martin Vingron	2	initiated this work and provided all necessary infrastructure	initiated this work and provided all necessary infrastructure	Conceived and designed the experiments	Conceptualization	YES
555765	15723697	Peter F. Arndt	2	worked on an appropriate alignment scoring scheme	worked on an appropriate alignment scoring scheme	Performed the experiments	Investigation	YES
555765	15723697	Peter F. Stadler	2	initiated this work and provided all necessary infrastructure	initiated this work and provided all necessary infrastructure	Conceived and designed the experiments	Conceptualization	YES
555765	15723697	RNA	2	elements in the multiple alignments of the corg database	elements in the multiple alignments of the corg database	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
555765	15723697	Stefan Ropcke	2	set up our database of binding site descriptions	set up our database of binding site descriptions	Performed the experiments|Contributed reagents/materials/analysis tools	Methodology|Software	YES
555765	15723697	Steffen Grossmann	2	annotated transcription factor binding sites and provided parts of the web interface	annotated transcription factor binding sites and provided parts of the web interface	Contributed reagents/materials/analysis tools	Software	YES
4412628	25919283	AA	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412628	25919283	AA	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412628	25919283	AA	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412628	25919283	KZ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412628	25919283	KZ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412628	25919283	KZ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412628	25919283	NH	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412628	25919283	NH	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412628	25919283	NH	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412628	25919283	RH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412628	25919283	RH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412628	25919283	RH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412628	25919283	SN	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412628	25919283	SN	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412628	25919283	SN	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412628	25919283	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412628	25919283	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412628	25919283	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412628	25919283	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3215167	21992467	JS	2	conceived of the study, and participated in its design and coordination and helped to draft the manuscript	conceived of the study, and participated in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
3215167	21992467	MT	2	was the principle investigator of the study|conceived of the study, and participated in its design and coordination and helped to draft the manuscript	was the principle investigator of the study	-	-	NO
3215167	21992467	MT	2	was the principle investigator of the study|conceived of the study, and participated in its design and coordination and helped to draft the manuscript	conceived of the study, and participated in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
3215167	21992467	NM	2	provided the supplements and proposed the idea of the study	provided the supplements and proposed the idea of the study	Conceived and designed the experiments	Conceptualization	YES
3215167	21992467	RP	2	aided with data collection and analysis|conceived of the study, and participated in its design and coordination and helped to draft the manuscript	aided with data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3215167	21992467	RP	2	aided with data collection and analysis|conceived of the study, and participated in its design and coordination and helped to draft the manuscript	conceived of the study, and participated in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
4590913	26464857	Ayaz Ghouse	2	was responsible for drafting the protocol, getting ethical approvals, collecting data, and preparing the first draft	was responsible for drafting the protocol, getting ethical approvals, collecting data, and preparing the first draft	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
4590913	26464857	Aysha Almas	2	conceived the idea and reviewed the protocol, ethical approvals, data analysis, and reviewing paper	conceived the idea and reviewed the protocol, ethical approvals, data analysis, and reviewing paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Review & Editing	YES
4590913	26464857	Munawwar Khursheed	2	was involved in recruitment of patients and data collection	was involved in recruitment of patients and data collection	Performed the experiments	Investigation	YES
4590913	26464857	Raza Iftikhar	2	was involved in data collection and paper writing	was involved in data collection and paper writing	Performed the experiments|Wrote the paper	Investigation	YES
5794845	28795390	D. All	2	authors interpreted the results and contributed to the writing of the manuscript	authors interpreted the results and contributed to the writing of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
1864997	17505534	JA	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1864997	17505534	JA	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1864997	17505534	JH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1864997	17505534	JH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1864997	17505534	JH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1864997	17505534	PB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1864997	17505534	PB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1864997	17505534	PB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1864997	17505534	PB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1864997	17505534	RA	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1864997	17505534	RA	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1864997	17505534	RM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1864997	17505534	RM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1864997	17505534	WL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1864997	17505534	WL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1864997	17505534	YT	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1864997	17505534	YT	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5696355	29201034	QL	PLoS52	accomplished the experiments	accomplished the experiments	-	-	NO
5696355	29201034	YL	PLoS52	accomplished the experiments	accomplished the experiments	-	-	NO
5696355	29201034	YT	PLoS52	accomplished the experiments|analyzed the data	accomplished the experiments	-	-	NO
5696355	29201034	YT	PLoS52	accomplished the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
4588361	26451372	Alberto Urrets-Zavalia	2	equally contributed to this work	equally contributed to this work	-	-	NO
4588361	26451372	Horacio Marcelo Serra	2	equally contributed to this work	equally contributed to this work	-	-	NO
5937304	29770190	All authors	2	critically reviewed the manuscript	critically reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5937304	29770190	CU	2	conducted animal experiments	conducted animal experiments	Performed the experiments	Investigation	YES
5937304	29770190	KM	2	conducted animal experiments	conducted animal experiments	Performed the experiments	Investigation	YES
5937304	29770190	KU	2	conducted animal experiments	conducted animal experiments	Performed the experiments	Investigation	YES
5937304	29770190	RI	2	conducted data analyses	conducted data analyses	Analyzed the data	Formal analysis	YES
5937304	29770190	TT	2	conducted animal experiments	conducted animal experiments	Performed the experiments	Investigation	YES
5937304	29770190	YB	2	conducted data analyses	conducted data analyses	Analyzed the data	Formal analysis	YES
5937304	29770190	YH	2	conceived the project and prepared the manuscript|conducted animal experiments|conducted animal experiments|conducted data analyses|supervised all aspects of the study	conceived the project and prepared the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5937304	29770190	YH	2	conceived the project and prepared the manuscript|conducted animal experiments|conducted animal experiments|conducted data analyses|supervised all aspects of the study	conducted animal experiments	Performed the experiments	Investigation	YES
5937304	29770190	YH	2	conceived the project and prepared the manuscript|conducted animal experiments|conducted animal experiments|conducted data analyses|supervised all aspects of the study	conducted animal experiments	Performed the experiments	Investigation	YES
5937304	29770190	YH	2	conceived the project and prepared the manuscript|conducted animal experiments|conducted animal experiments|conducted data analyses|supervised all aspects of the study	conducted data analyses	Analyzed the data	Formal analysis	YES
5937304	29770190	YH	2	conceived the project and prepared the manuscript|conducted animal experiments|conducted animal experiments|conducted data analyses|supervised all aspects of the study	supervised all aspects of the study	-	Supervision	YES
5937304	29770190	YN	2	conceived the project and prepared the manuscript|supervised all aspects of the study	conceived the project and prepared the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5937304	29770190	YN	2	conceived the project and prepared the manuscript|supervised all aspects of the study	supervised all aspects of the study	-	Supervision	YES
5937304	29770190	YT	2	conducted data analyses	conducted data analyses	Analyzed the data	Formal analysis	YES
555766	15733327	MT	2	participated in the design and coordination of the study	participated in the design and coordination of the study	Conceived and designed the experiments	Methodology|Project administration	YES
555766	15733327	SF	2	carried out the computational and statistical analysis, and drafted the manuscript	carried out the computational and statistical analysis, and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
555766	15733327	TW	2	participated in the design and coordination of the study	participated in the design and coordination of the study	Conceived and designed the experiments	Methodology|Project administration	YES
4412629	25919661	AS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4412629	25919661	AS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4412629	25919661	CD	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412629	25919661	DL	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412629	25919661	DL	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412629	25919661	HZ	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4412629	25919661	HZ	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4412629	25919661	KT	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412629	25919661	RW	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412629	25919661	RW	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412629	25919661	SC	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412629	25919661	SC	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3215636	22032491	JMW	2	involved in drafting the manuscript and revising of the manuscript	involved in drafting the manuscript and revising of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3215636	22032491	PRO	2	conceived of and designed this study, contributed to the acquisition, analysis and interpretation of data	conceived of and designed this study, contributed to the acquisition, analysis and interpretation of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Methodology|Resources	YES
3215636	22032491	RB	2	involved in drafting the manuscript and revising of the manuscript	involved in drafting the manuscript and revising of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3215636	22032491	RDL	2	assisted data interpretation and manuscript preparation	assisted data interpretation and manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3215636	22032491	RS	2	assisted the design of the study, data interpretation and manuscript preparation	assisted the design of the study, data interpretation and manuscript preparation	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3215636	22032491	SJF	2	conceived of the study, and participated in its design and helped to draft the manuscript	conceived of the study, and participated in its design and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
3215636	22032491	TPSJ	2	conceived of and designed this study, contributed to the acquisition, analysis and interpretation of data, led the drafting and revising of the manuscript	conceived of and designed this study, contributed to the acquisition, analysis and interpretation of data, led the drafting and revising of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5436995	28523582	AFG	2	are responsible for the design of the study|are responsible for the approval of the final form	are responsible for the design of the study	Conceived and designed the experiments	Methodology	YES
5436995	28523582	AFG	2	are responsible for the design of the study|are responsible for the approval of the final form	are responsible for the approval of the final form	-	-	NO
5436995	28523582	DV	2	are responsible for the design of the study|are responsible for the data acquisition|are responsible for the approval of the final form	are responsible for the design of the study	Conceived and designed the experiments	Methodology	YES
5436995	28523582	DV	2	are responsible for the design of the study|are responsible for the data acquisition|are responsible for the approval of the final form	are responsible for the data acquisition	Performed the experiments	Investigation	YES
5436995	28523582	DV	2	are responsible for the design of the study|are responsible for the data acquisition|are responsible for the approval of the final form	are responsible for the approval of the final form	-	-	NO
5436995	28523582	ED	2	are responsible for the design of the study|are responsible for the data acquisition|are responsible for the approval of the final form	are responsible for the design of the study	Conceived and designed the experiments	Methodology	YES
5436995	28523582	ED	2	are responsible for the design of the study|are responsible for the data acquisition|are responsible for the approval of the final form	are responsible for the data acquisition	Performed the experiments	Investigation	YES
5436995	28523582	ED	2	are responsible for the design of the study|are responsible for the data acquisition|are responsible for the approval of the final form	are responsible for the approval of the final form	-	-	NO
5436995	28523582	FB	2	are responsible for the design of the study|are responsible for the data acquisition|are responsible for the approval of the final form	are responsible for the design of the study	Conceived and designed the experiments	Methodology	YES
5436995	28523582	FB	2	are responsible for the design of the study|are responsible for the data acquisition|are responsible for the approval of the final form	are responsible for the data acquisition	Performed the experiments	Investigation	YES
5436995	28523582	FB	2	are responsible for the design of the study|are responsible for the data acquisition|are responsible for the approval of the final form	are responsible for the approval of the final form	-	-	NO
5436995	28523582	FC	2	are responsible for the data analysis and critical evaluation of the results|are responsible for the manuscript writing|are responsible for the approval of the final form	are responsible for the data analysis and critical evaluation of the results	Analyzed the data	Formal analysis	YES
5436995	28523582	FC	2	are responsible for the data analysis and critical evaluation of the results|are responsible for the manuscript writing|are responsible for the approval of the final form	are responsible for the manuscript writing	Wrote the paper	Writing - Original Draft	YES
5436995	28523582	FC	2	are responsible for the data analysis and critical evaluation of the results|are responsible for the manuscript writing|are responsible for the approval of the final form	are responsible for the approval of the final form	-	-	NO
5436995	28523582	JOP	2	are responsible for the design of the study|are responsible for the data analysis and critical evaluation of the results|are responsible for the approval of the final form	are responsible for the design of the study	Conceived and designed the experiments	Methodology	YES
5436995	28523582	JOP	2	are responsible for the design of the study|are responsible for the data analysis and critical evaluation of the results|are responsible for the approval of the final form	are responsible for the data analysis and critical evaluation of the results	Analyzed the data	Formal analysis	YES
5436995	28523582	JOP	2	are responsible for the design of the study|are responsible for the data analysis and critical evaluation of the results|are responsible for the approval of the final form	are responsible for the approval of the final form	-	-	NO
5436995	28523582	MK	2	are responsible for the design of the study|are responsible for the data acquisition|are responsible for the approval of the final form	are responsible for the design of the study	Conceived and designed the experiments	Methodology	YES
5436995	28523582	MK	2	are responsible for the design of the study|are responsible for the data acquisition|are responsible for the approval of the final form	are responsible for the data acquisition	Performed the experiments	Investigation	YES
5436995	28523582	MK	2	are responsible for the design of the study|are responsible for the data acquisition|are responsible for the approval of the final form	are responsible for the approval of the final form	-	-	NO
5436995	28523582	PM	2	are responsible for the data acquisition|are responsible for the manuscript writing|are responsible for the approval of the final form	are responsible for the data acquisition	Performed the experiments	Investigation	YES
5436995	28523582	PM	2	are responsible for the data acquisition|are responsible for the manuscript writing|are responsible for the approval of the final form	are responsible for the manuscript writing	Wrote the paper	Writing - Original Draft	YES
5436995	28523582	PM	2	are responsible for the data acquisition|are responsible for the manuscript writing|are responsible for the approval of the final form	are responsible for the approval of the final form	-	-	NO
5436995	28523582	SB	2	are responsible for the design of the study|are responsible for the data acquisition|are responsible for the data analysis and critical evaluation of the results|are responsible for the approval of the final form	are responsible for the design of the study	Conceived and designed the experiments	Methodology	YES
5436995	28523582	SB	2	are responsible for the design of the study|are responsible for the data acquisition|are responsible for the data analysis and critical evaluation of the results|are responsible for the approval of the final form	are responsible for the data acquisition	Performed the experiments	Investigation	YES
5436995	28523582	SB	2	are responsible for the design of the study|are responsible for the data acquisition|are responsible for the data analysis and critical evaluation of the results|are responsible for the approval of the final form	are responsible for the data analysis and critical evaluation of the results	Analyzed the data	Formal analysis	YES
5436995	28523582	SB	2	are responsible for the design of the study|are responsible for the data acquisition|are responsible for the data analysis and critical evaluation of the results|are responsible for the approval of the final form	are responsible for the approval of the final form	-	-	NO
5436995	28523582	SG	2	are responsible for the design of the study|are responsible for the data acquisition|are responsible for the data analysis and critical evaluation of the results|are responsible for the manuscript writing|are responsible for the approval of the final form	are responsible for the design of the study	Conceived and designed the experiments	Methodology	YES
5436995	28523582	SG	2	are responsible for the design of the study|are responsible for the data acquisition|are responsible for the data analysis and critical evaluation of the results|are responsible for the manuscript writing|are responsible for the approval of the final form	are responsible for the data acquisition	Performed the experiments	Investigation	YES
5436995	28523582	SG	2	are responsible for the design of the study|are responsible for the data acquisition|are responsible for the data analysis and critical evaluation of the results|are responsible for the manuscript writing|are responsible for the approval of the final form	are responsible for the data analysis and critical evaluation of the results	Analyzed the data	Formal analysis	YES
5436995	28523582	SG	2	are responsible for the design of the study|are responsible for the data acquisition|are responsible for the data analysis and critical evaluation of the results|are responsible for the manuscript writing|are responsible for the approval of the final form	are responsible for the manuscript writing	Wrote the paper	Writing - Original Draft	YES
5436995	28523582	SG	2	are responsible for the design of the study|are responsible for the data acquisition|are responsible for the data analysis and critical evaluation of the results|are responsible for the manuscript writing|are responsible for the approval of the final form	are responsible for the approval of the final form	-	-	NO
5436995	28523582	VD	2	are responsible for the design of the study|are responsible for the data acquisition|are responsible for the approval of the final form	are responsible for the design of the study	Conceived and designed the experiments	Methodology	YES
5436995	28523582	VD	2	are responsible for the design of the study|are responsible for the data acquisition|are responsible for the approval of the final form	are responsible for the data acquisition	Performed the experiments	Investigation	YES
5436995	28523582	VD	2	are responsible for the design of the study|are responsible for the data acquisition|are responsible for the approval of the final form	are responsible for the approval of the final form	-	-	NO
6070837	30112164	AM	7	Contributions to the conception or design of the work and final approval of the article|Contributions to the conception or design of the work analysis, or interpretation of data for the work; and final approval of the article	Contributions to the conception or design of the work and final approval of the article	Conceived and designed the experiments	Conceptualization	YES
6070837	30112164	AM	7	Contributions to the conception or design of the work and final approval of the article|Contributions to the conception or design of the work analysis, or interpretation of data for the work; and final approval of the article	Contributions to the conception or design of the work analysis, or interpretation of data for the work; and final approval of the article	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Resources	YES
6070837	30112164	HM	7	Contributions to the conception or design of the interpretation of data for the work; and final approval of the article	Contributions to the conception or design of the interpretation of data for the work; and final approval of the article	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Resources	YES
6070837	30112164	OR	7	Contributions the acquisition and analysis of data for the work and drafting the article	Contributions the acquisition and analysis of data for the work and drafting the article	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft	YES
1864998	17505535	AG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1864998	17505535	AG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1864998	17505535	AG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1864998	17505535	AG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1864998	17505535	GM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1864998	17505535	GM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1864998	17505535	GM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1864998	17505535	GM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1864998	17505535	GP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1864998	17505535	GP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1864998	17505535	GP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1864998	17505535	GP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6001250	29997879	J.Z.	2	conceived the project, analyzed the results, and wrote the manuscript	conceived the project, analyzed the results, and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
6001250	29997879	Q.J.	2	synthesized the ucnp-pa-ti	synthesized the ucnp-pa-ti	Performed the experiments	Investigation	YES
6001250	29997879	X.Z.	2	synthesized the ucnp-pa-ti	synthesized the ucnp-pa-ti	Performed the experiments	Investigation	YES
6001250	29997879	Y.L.	2	conceived the project, analyzed the results, and wrote the manuscript|conducted other experiments	conceived the project, analyzed the results, and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
6001250	29997879	Y.L.	2	conceived the project, analyzed the results, and wrote the manuscript|conducted other experiments	conducted other experiments	Performed the experiments	Investigation	YES
5696356	29201035	AZ	2	analyzed, discussed results and wrote the manuscript	analyzed, discussed results and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5696356	29201035	AZ-G	2	prepared figures	prepared figures	-	Visualization	YES
5696356	29201035	KR	2	contributed with analysis tools|analyzed, discussed results and wrote the manuscript	contributed with analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5696356	29201035	KR	2	contributed with analysis tools|analyzed, discussed results and wrote the manuscript	analyzed, discussed results and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5696356	29201035	MF-E	2	prepared figures|analyzed, discussed results and wrote the manuscript	prepared figures	-	Visualization	YES
5696356	29201035	MF-E	2	prepared figures|analyzed, discussed results and wrote the manuscript	analyzed, discussed results and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5696356	29201035	MG-M	2	contributed with analysis tools|prepared figures	contributed with analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5696356	29201035	MG-M	2	contributed with analysis tools|prepared figures	prepared figures	-	Visualization	YES
5696356	29201035	MR	2	analyzed, discussed results and wrote the manuscript	analyzed, discussed results and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5696356	29201035	TG	2	analyzed, discussed results and wrote the manuscript	analyzed, discussed results and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5440420	28534134	AD	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5440420	28534134	AL	2	performed the sample analysis|wrote the manuscript	performed the sample analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5440420	28534134	AL	2	performed the sample analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3219660	22013987	AZJ	2	conceived of the study, collected and analysed data, and wrote the manuscript	conceived of the study, collected and analysed data, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
3219660	22013987	All authors	2	reviewed and approved the manuscript	reviewed and approved the manuscript	Wrote the paper	Writing - Review & Editing	YES
3219660	22013987	CY	2	collected and analysed data	collected and analysed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3219660	22013987	IF	2	participated in the design of the study, analysed data and reviewed the manuscript	participated in the design of the study, analysed data and reviewed the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
3219660	22013987	MGN	2	analysed data and performed the statistical analysis	analysed data and performed the statistical analysis	Analyzed the data	Formal analysis	YES
3219660	22013987	SR	2	analysed data	analysed data	Analyzed the data	Formal analysis	YES
3219660	22013987	TT	2	collected and analysed data	collected and analysed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3219660	22013987	VP	2	analysed data and reviewed the manuscript	analysed data and reviewed the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
3219660	22013987	YK	2	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5558184	28812539	All authors	2	wrote the manuscript, they have all read and approved the manuscript	wrote the manuscript, they have all read and approved the manuscript	Wrote the paper	Writing - Original Draft	YES
5558184	28812539	FC	2	performed experiments|analysed data	performed experiments	Performed the experiments	Investigation	YES
5558184	28812539	FC	2	performed experiments|analysed data	analysed data	Analyzed the data	Formal analysis	YES
5558184	28812539	FF	2	devised the research|analysed data	devised the research	Conceived and designed the experiments	Conceptualization	YES
5558184	28812539	FF	2	devised the research|analysed data	analysed data	Analyzed the data	Formal analysis	YES
5558184	28812539	JM	2	performed experiments|analysed data	performed experiments	Performed the experiments	Investigation	YES
5558184	28812539	JM	2	performed experiments|analysed data	analysed data	Analyzed the data	Formal analysis	YES
5558184	28812539	MM	2	analysed data	analysed data	Analyzed the data	Formal analysis	YES
5558184	28812539	MNW	2	devised the research|analysed data	devised the research	Conceived and designed the experiments	Conceptualization	YES
5558184	28812539	MNW	2	devised the research|analysed data	analysed data	Analyzed the data	Formal analysis	YES
5558184	28812539	MP	2	performed experiments|analysed data	performed experiments	Performed the experiments	Investigation	YES
5558184	28812539	MP	2	performed experiments|analysed data	analysed data	Analyzed the data	Formal analysis	YES
4412630	25919298	C-HP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412630	25919298	C-HP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412630	25919298	C-HP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412630	25919298	C-HP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412630	25919298	C-KL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4412630	25919298	C-KL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412630	25919298	CA	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4412630	25919298	D-KL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4412630	25919298	JYH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4412630	25919298	K-JU	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4412630	25919298	S-CY	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4412630	25919298	S-CY	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412630	25919298	Y-HJ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
3224778	22074365	RJA	2	was responsible for literature review and manuscript preparation	was responsible for literature review and manuscript preparation	Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
3224778	22074365	RJB	2	was responsible for the study design, biochemical work, statistical analyses, and manuscript preparation	was responsible for the study design, biochemical work, statistical analyses, and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
1865387	17505540	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1865387	17505540	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1865387	17505540	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1865387	17505540	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1865387	17505540	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1865387	17505540	MM	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1865387	17505540	RO	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1865387	17505540	RO	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1865387	17505540	TG	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5442037	28536967	DK	2	participated in the image analysis and data interpretation	participated in the image analysis and data interpretation	Analyzed the data	Formal analysis|Visualization	YES
5442037	28536967	HB	2	participated in data interpretation and revision of the manuscript	participated in data interpretation and revision of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5442037	28536967	IK	2	participated in data collection and analysis	participated in data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5442037	28536967	JM	2	participated in data interpretation and revision of the manuscript	participated in data interpretation and revision of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5442037	28536967	KM	2	participated in data interpretation and revision of the manuscript	participated in data interpretation and revision of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5442037	28536967	KP	2	participated in the image analysis and data interpretation	participated in the image analysis and data interpretation	Analyzed the data	Formal analysis|Visualization	YES
5442037	28536967	SC	2	participated in the image analysis and data interpretation	participated in the image analysis and data interpretation	Analyzed the data	Formal analysis|Visualization	YES
5442037	28536967	SJ	2	participated in data interpretation and revision of the manuscript	participated in data interpretation and revision of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5442037	28536967	SK	2	participated in the image analysis and data interpretation|participated in the study design, image analysis, data interpretation, and manuscript revision	participated in the image analysis and data interpretation	Analyzed the data	Formal analysis|Visualization	YES
5442037	28536967	SK	2	participated in the image analysis and data interpretation|participated in the study design, image analysis, data interpretation, and manuscript revision	participated in the study design, image analysis, data interpretation, and manuscript revision	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Visualization|Writing - Review & Editing	YES
5442037	28536967	SL	2	participated in data collection and analysis	participated in data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5442037	28536967	TJ	2	participated in data collection and data analysis and prepared the manuscript	participated in data collection and data analysis and prepared the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5442037	28536967	WJ	2	participated in data interpretation and revision of the manuscript	participated in data interpretation and revision of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5558185	28812537	AK	2	initiated the project and contributed to the method|developed and implemented the algorithm|performed the benchmarking study and comparison to alternative tools|wrote the manuscript	initiated the project and contributed to the method	Conceived and designed the experiments|Performed the experiments	Conceptualization	YES
5558185	28812537	AK	2	initiated the project and contributed to the method|developed and implemented the algorithm|performed the benchmarking study and comparison to alternative tools|wrote the manuscript	developed and implemented the algorithm	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5558185	28812537	AK	2	initiated the project and contributed to the method|developed and implemented the algorithm|performed the benchmarking study and comparison to alternative tools|wrote the manuscript	performed the benchmarking study and comparison to alternative tools	Performed the experiments	Investigation	YES
5558185	28812537	AK	2	initiated the project and contributed to the method|developed and implemented the algorithm|performed the benchmarking study and comparison to alternative tools|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5558185	28812537	DRR	2	initiated the project and contributed to the method	initiated the project and contributed to the method	Conceived and designed the experiments|Performed the experiments	Conceptualization	YES
5558185	28812537	QIAGENs	2	ontology and knowledge base	ontology and knowledge base	-	-	NO
5558185	28812537	RAR	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5558185	28812537	SS	2	initiated the project and contributed to the method|performed the benchmarking study and comparison to alternative tools|wrote the manuscript	initiated the project and contributed to the method	Conceived and designed the experiments|Performed the experiments	Conceptualization	YES
5558185	28812537	SS	2	initiated the project and contributed to the method|performed the benchmarking study and comparison to alternative tools|wrote the manuscript	performed the benchmarking study and comparison to alternative tools	Performed the experiments	Investigation	YES
5558185	28812537	SS	2	initiated the project and contributed to the method|performed the benchmarking study and comparison to alternative tools|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5558185	28812537	ST	2	provided guidance and project management for commercialization|performed the benchmarking study and comparison to alternative tools|wrote the manuscript	provided guidance and project management for commercialization	-	Project administration|Supervision	YES
5558185	28812537	ST	2	provided guidance and project management for commercialization|performed the benchmarking study and comparison to alternative tools|wrote the manuscript	performed the benchmarking study and comparison to alternative tools	Performed the experiments	Investigation	YES
5558185	28812537	ST	2	provided guidance and project management for commercialization|performed the benchmarking study and comparison to alternative tools|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6070839	30112166	DCS	7	Investigation, formal analysis, review & editing	Investigation, formal analysis, review & editing	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
6070839	30112166	HH	7	Resources, conceptualization, methodology, investigation, formal analysis, visualization and original draft preparation	Resources, conceptualization, methodology, investigation, formal analysis, visualization and original draft preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Resources|Visualization|Writing - Original Draft	YES
6070839	30112166	PP	7	Methodology, conceptualization, formal analysis, review & editing	Methodology, conceptualization, formal analysis, review & editing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Review & Editing	YES
6070839	30112166	TM	7	Investigation, data curation, formal analysis, visualization and original draft preparation	Investigation, data curation, formal analysis, visualization and original draft preparation	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Formal analysis|Investigation|Visualization|Writing - Original Draft	YES
6070839	30112166	VW	7	Methodology, supervision, review & editing	Methodology, supervision, review & editing	Performed the experiments|Wrote the paper	Methodology|Supervision|Writing - Review & Editing	YES
3229558	22087604	BTB	2	participated in data collection, statistical analysis, and manuscript preparation	participated in data collection, statistical analysis, and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3229558	22087604	CSS	2	participated in data collection, statistical analysis, and manuscript preparation	participated in data collection, statistical analysis, and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3229558	22087604	DRB	2	participated in data collection, statistical analysis, and manuscript preparation	participated in data collection, statistical analysis, and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3229558	22087604	MAP	2	participated in data collection, statistical analysis, and manuscript preparation	participated in data collection, statistical analysis, and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3229558	22087604	NRR	2	served as the principal investigator and contributed to study design, data collection, and manuscript preparation	served as the principal investigator and contributed to study design, data collection, and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Funding acquisition|Investigation|Methodology|Resources|Writing - Original Draft	YES
3229558	22087604	PCG	2	participated in data collection, statistical analysis, and manuscript preparation	participated in data collection, statistical analysis, and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3229558	22087604	SMP	2	participated in manuscript preparation	participated in manuscript preparation	Wrote the paper	Writing - Original Draft	YES
5696362	29201032	BP	2	performed most of the experiments, analyzed results and wrote most of the paper|provided financial support, helped in planning, executing and leading the project|were involved in manuscript preparation	performed most of the experiments, analyzed results and wrote most of the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5696362	29201032	BP	2	performed most of the experiments, analyzed results and wrote most of the paper|provided financial support, helped in planning, executing and leading the project|were involved in manuscript preparation	provided financial support, helped in planning, executing and leading the project	Conceived and designed the experiments|Performed the experiments	Funding acquisition|Investigation|Methodology	YES
5696362	29201032	BP	2	performed most of the experiments, analyzed results and wrote most of the paper|provided financial support, helped in planning, executing and leading the project|were involved in manuscript preparation	were involved in manuscript preparation	Wrote the paper	Writing - Original Draft	YES
5696362	29201032	CG	2	advised, helped in data analysis and supported with further ideas and experiments for the project|were involved in manuscript preparation	advised, helped in data analysis and supported with further ideas and experiments for the project	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation	YES
5696362	29201032	CG	2	advised, helped in data analysis and supported with further ideas and experiments for the project|were involved in manuscript preparation	were involved in manuscript preparation	Wrote the paper	Writing - Original Draft	YES
5696362	29201032	EJ	2	were involved in manuscript preparation	were involved in manuscript preparation	Wrote the paper	Writing - Original Draft	YES
5696362	29201032	LD	2	performed most of the experiments, analyzed results and wrote most of the paper|advised, helped in data analysis and supported with further ideas and experiments for the project|were involved in manuscript preparation	performed most of the experiments, analyzed results and wrote most of the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5696362	29201032	LD	2	performed most of the experiments, analyzed results and wrote most of the paper|advised, helped in data analysis and supported with further ideas and experiments for the project|were involved in manuscript preparation	advised, helped in data analysis and supported with further ideas and experiments for the project	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation	YES
5696362	29201032	LD	2	performed most of the experiments, analyzed results and wrote most of the paper|advised, helped in data analysis and supported with further ideas and experiments for the project|were involved in manuscript preparation	were involved in manuscript preparation	Wrote the paper	Writing - Original Draft	YES
4412631	25919139	JA	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412631	25919139	JA	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412631	25919139	LK	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412631	25919139	LK	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412631	25919139	PN	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412631	25919139	PP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4412631	25919139	RS	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412631	25919139	SKS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412631	25919139	SKS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412631	25919139	SKS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412631	25919139	SKS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412631	25919139	SM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4412631	25919139	SPG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412631	25919139	SPG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412631	25919139	SPG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6070840	30112165	AK	7	Contributions the acquisition and analysis of data for the work and Drafting the article	Contributions the acquisition and analysis of data for the work and Drafting the article	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft	YES
6070840	30112165	AZ	7	Contributions to the data collection, data entry, conception or design, and final approval of the article	Contributions to the data collection, data entry, conception or design, and final approval of the article	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Data curation|Investigation|Resources	YES
6070840	30112165	HM	7	Contributions to the conception or design of the work and final approval of the article	Contributions to the conception or design of the work and final approval of the article	Conceived and designed the experiments	Conceptualization	YES
6070840	30112165	MS	7	Contributions to the data collection, data entry, conception or design, and final approval of the article	Contributions to the data collection, data entry, conception or design, and final approval of the article	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Data curation|Investigation|Resources	YES
6070840	30112165	SP	7	Contributions to the conception or design of the interpretation of data for the work, and final approval of the article	Contributions to the conception or design of the interpretation of data for the work, and final approval of the article	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Resources	YES
5558187	28812535	HJM	2	devised the research|performed protein analyses|performed statistical analyses|wrote the manuscript with contributions from all authors	devised the research	Conceived and designed the experiments	Conceptualization	YES
5558187	28812535	HJM	2	devised the research|performed protein analyses|performed statistical analyses|wrote the manuscript with contributions from all authors	performed protein analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5558187	28812535	HJM	2	devised the research|performed protein analyses|performed statistical analyses|wrote the manuscript with contributions from all authors	performed statistical analyses	Analyzed the data	Formal analysis	YES
5558187	28812535	HJM	2	devised the research|performed protein analyses|performed statistical analyses|wrote the manuscript with contributions from all authors	wrote the manuscript with contributions from all authors	Wrote the paper	Writing - Original Draft	YES
5558187	28812535	JFM	2	performed protein analyses	performed protein analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5558187	28812535	KAW	2	devised the research|performed statistical analyses	devised the research	Conceived and designed the experiments	Conceptualization	YES
5558187	28812535	KAW	2	devised the research|performed statistical analyses	performed statistical analyses	Analyzed the data	Formal analysis	YES
5558187	28812535	KT	2	devised the research	devised the research	Conceived and designed the experiments	Conceptualization	YES
5558187	28812535	MNW	2	devised the research|performed protein analyses|wrote the manuscript with contributions from all authors	devised the research	Conceived and designed the experiments	Conceptualization	YES
5558187	28812535	MNW	2	devised the research|performed protein analyses|wrote the manuscript with contributions from all authors	performed protein analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5558187	28812535	MNW	2	devised the research|performed protein analyses|wrote the manuscript with contributions from all authors	wrote the manuscript with contributions from all authors	Wrote the paper	Writing - Original Draft	YES
5558187	28812535	ZK	2	performed statistical analyses	performed statistical analyses	Analyzed the data	Formal analysis	YES
5442040	28536968	AH	2	collected clinical parameters and performed the clinical cohort analysis, helped with statistical analysis and manuscript preparation	collected clinical parameters and performed the clinical cohort analysis, helped with statistical analysis and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5442040	28536968	DB	2	facilitated overall study concept and design, advised on data analysis techniques and aided in manuscript preparation	facilitated overall study concept and design, advised on data analysis techniques and aided in manuscript preparation	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
5442040	28536968	DC	2	aided in database management, derivation of clinical parameters, statistical analysis advice and manuscript review	aided in database management, derivation of clinical parameters, statistical analysis advice and manuscript review	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Software|Writing - Review & Editing	YES
5442040	28536968	EB	2	aided in study design, advised on clinical protocols and aided in manuscript production	aided in study design, advised on clinical protocols and aided in manuscript production	Conceived and designed the experiments	Methodology	YES
5442040	28536968	KW	2	led the study design, performed data analysis, and was the primary manuscript producer	led the study design, performed data analysis, and was the primary manuscript producer	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology|Writing - Original Draft	YES
5442040	28536968	MT	2	aided in study design and manuscript production	aided in study design and manuscript production	Conceived and designed the experiments	Methodology	YES
5442040	28536968	NP	2	provided input on study design and clinical protocols and manuscript review	provided input on study design and clinical protocols and manuscript review	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5442040	28536968	RM	2	provided input on study design and clinical protocols and manuscript review	provided input on study design and clinical protocols and manuscript review	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5442040	28536968	SC	2	provided input on study design and clinical protocols and manuscript review	provided input on study design and clinical protocols and manuscript review	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
1865388	17505541	PS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1865388	17505541	PS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1865388	17505541	PS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1865388	17505541	PS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1865388	17505541	PS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4589576	26457298	Danfeng Zhang	2	contributed equally to the paper	contributed equally to the paper	-	-	NO
4589576	26457298	Hai Jin	2	contributed equally to the paper	contributed equally to the paper	-	-	NO
4589576	26457298	Shun Gong	2	contributed equally to the paper	contributed equally to the paper	-	-	NO
3231804	22068021	DSW	2	conceived the study, developed the study design, secured the funding for the project, assisted and provided oversight for all data acquisition and statistical analysis, assisted and provided oversight in drafting the manuscript, and served as the faculty mentor and principal investigator for the project	conceived the study, developed the study design, secured the funding for the project, assisted and provided oversight for all data acquisition and statistical analysis, assisted and provided oversight in drafting the manuscript, and served as the faculty mentor and principal investigator for the project	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Funding acquisition|Investigation|Methodology|Resources|Supervision|Writing - Original Draft	YES
3231804	22068021	GH	2	helped with exercise sessions biochemical analysis	helped with exercise sessions biochemical analysis	Performed the experiments	Investigation	YES
3231804	22068021	MC	2	coordinated the study, carried out the exercise sessions and all analyses, and drafted the manuscript	coordinated the study, carried out the exercise sessions and all analyses, and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Project administration|Writing - Original Draft	YES
3231804	22068021	PLB	2	carried out the exercise sessions and helped with analysis	carried out the exercise sessions and helped with analysis	Performed the experiments	Investigation	YES
4412632	25919690	GPG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Revised the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412632	25919690	GPG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Revised the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412632	25919690	GPG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Revised the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412632	25919690	GPG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Revised the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412632	25919690	GPG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Revised the paper	Revised the paper	Wrote the paper	Writing - Review & Editing	YES
4412632	25919690	GTS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412632	25919690	GTS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412632	25919690	GTS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412632	25919690	GTS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412632	25919690	GTS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412632	25919690	LW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Revised the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412632	25919690	LW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Revised the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412632	25919690	LW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Revised the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412632	25919690	LW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Revised the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412632	25919690	LW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Revised the paper	Revised the paper	Wrote the paper	Writing - Review & Editing	YES
4412632	25919690	XYH	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6070841	30112167	NM	2	contributed to the supply of reagents and corrected the manuscript	contributed to the supply of reagents and corrected the manuscript	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Review & Editing	YES
6070841	30112167	QL	2	conceived the study, designed the algorithms, performed the experiment, analyzed the experiment results, and wrote the manuscript	conceived the study, designed the algorithms, performed the experiment, analyzed the experiment results, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Software|Writing - Original Draft	YES
6070841	30112167	YT	2	contributed for reagents, conducted the western blot experiments, and a detailed correction of the manuscript	contributed for reagents, conducted the western blot experiments, and a detailed correction of the manuscript	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Resources|Writing - Review & Editing	YES
5696719	29201036	CP	2	conducted the field and laboratory experiments	conducted the field and laboratory experiments	Performed the experiments	Investigation	YES
5696719	29201036	HY	2	conducted the field and laboratory experiments	conducted the field and laboratory experiments	Performed the experiments	Investigation	YES
5696719	29201036	JW	2	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5696719	29201036	QL	2	conducted the field and laboratory experiments	conducted the field and laboratory experiments	Performed the experiments	Investigation	YES
5696719	29201036	RZ	2	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5696719	29201036	XS	2	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5696719	29201036	YY	2	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5558188	28812538	NP	2	generated part of the data and of the data analyses	generated part of the data and of the data analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5558188	28812538	XC	2	conceived the study, analyzed the data and wrote the article	conceived the study, analyzed the data and wrote the article	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
1865389	17505542	AM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1865389	17505542	AM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1865389	17505542	BB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Conceived the study, selected the analytical tools, conducted the behavioral experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1865389	17505542	BB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Conceived the study, selected the analytical tools, conducted the behavioral experiments	Performed the experiments	Performed the experiments	Investigation	YES
1865389	17505542	BB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Conceived the study, selected the analytical tools, conducted the behavioral experiments	Analyzed the data	Analyzed the data	Formal analysis	YES
1865389	17505542	BB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Conceived the study, selected the analytical tools, conducted the behavioral experiments	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1865389	17505542	BB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Conceived the study, selected the analytical tools, conducted the behavioral experiments	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1865389	17505542	BB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Conceived the study, selected the analytical tools, conducted the behavioral experiments	Conceived the study, selected the analytical tools, conducted the behavioral experiments	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
1865389	17505542	CH	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1865389	17505542	GS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5445063	28547129	AB	2	carried out the data analysis and interpretation	carried out the data analysis and interpretation	Analyzed the data	Formal analysis	YES
5445063	28547129	All authors	2	contributed to the final approval of the version to be published	contributed to the final approval of the version to be published	-	-	NO
5445063	28547129	CC	2	contributed to the conception or design of the data collection|contributed to the conception or design of the analysis|carried out the data analysis and interpretation|participated in the drafting of the article	contributed to the conception or design of the data collection	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceptualization|Investigation|Resources	YES
5445063	28547129	CC	2	contributed to the conception or design of the data collection|contributed to the conception or design of the analysis|carried out the data analysis and interpretation|participated in the drafting of the article	contributed to the conception or design of the analysis	Conceived and designed the experiments	Conceptualization	YES
5445063	28547129	CC	2	contributed to the conception or design of the data collection|contributed to the conception or design of the analysis|carried out the data analysis and interpretation|participated in the drafting of the article	carried out the data analysis and interpretation	Analyzed the data	Formal analysis	YES
5445063	28547129	CC	2	contributed to the conception or design of the data collection|contributed to the conception or design of the analysis|carried out the data analysis and interpretation|participated in the drafting of the article	participated in the drafting of the article	Wrote the paper	Writing - Original Draft	YES
5445063	28547129	DM	2	contributed to the conception or design of the data collection|contributed to the conception or design of the analysis|participated in the data collection|carried out the critical revision of the article	contributed to the conception or design of the data collection	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceptualization|Investigation|Resources	YES
5445063	28547129	DM	2	contributed to the conception or design of the data collection|contributed to the conception or design of the analysis|participated in the data collection|carried out the critical revision of the article	contributed to the conception or design of the analysis	Conceived and designed the experiments	Conceptualization	YES
5445063	28547129	DM	2	contributed to the conception or design of the data collection|contributed to the conception or design of the analysis|participated in the data collection|carried out the critical revision of the article	participated in the data collection	Performed the experiments	Investigation	YES
5445063	28547129	DM	2	contributed to the conception or design of the data collection|contributed to the conception or design of the analysis|participated in the data collection|carried out the critical revision of the article	carried out the critical revision of the article	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5445063	28547129	FW	2	carried out the data analysis and interpretation|participated in the drafting of the article|carried out the critical revision of the article	carried out the data analysis and interpretation	Analyzed the data	Formal analysis	YES
5445063	28547129	FW	2	carried out the data analysis and interpretation|participated in the drafting of the article|carried out the critical revision of the article	participated in the drafting of the article	Wrote the paper	Writing - Original Draft	YES
5445063	28547129	FW	2	carried out the data analysis and interpretation|participated in the drafting of the article|carried out the critical revision of the article	carried out the critical revision of the article	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5445063	28547129	IW	2	contributed to the conception or design of the data collection|contributed to the conception or design of the analysis|carried out the critical revision of the article	contributed to the conception or design of the data collection	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceptualization|Investigation|Resources	YES
5445063	28547129	IW	2	contributed to the conception or design of the data collection|contributed to the conception or design of the analysis|carried out the critical revision of the article	contributed to the conception or design of the analysis	Conceived and designed the experiments	Conceptualization	YES
5445063	28547129	IW	2	contributed to the conception or design of the data collection|contributed to the conception or design of the analysis|carried out the critical revision of the article	carried out the critical revision of the article	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5445063	28547129	JC	2	contributed to the conception or design of the data collection|contributed to the conception or design of the analysis|carried out the critical revision of the article	contributed to the conception or design of the data collection	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceptualization|Investigation|Resources	YES
5445063	28547129	JC	2	contributed to the conception or design of the data collection|contributed to the conception or design of the analysis|carried out the critical revision of the article	contributed to the conception or design of the analysis	Conceived and designed the experiments	Conceptualization	YES
5445063	28547129	JC	2	contributed to the conception or design of the data collection|contributed to the conception or design of the analysis|carried out the critical revision of the article	carried out the critical revision of the article	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5445063	28547129	MF	2	contributed to the conception or design of the data collection|contributed to the conception or design of the analysis|participated in the data collection|carried out the data analysis and interpretation|participated in the drafting of the article|carried out the critical revision of the article	contributed to the conception or design of the data collection	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceptualization|Investigation|Resources	YES
5445063	28547129	MF	2	contributed to the conception or design of the data collection|contributed to the conception or design of the analysis|participated in the data collection|carried out the data analysis and interpretation|participated in the drafting of the article|carried out the critical revision of the article	contributed to the conception or design of the analysis	Conceived and designed the experiments	Conceptualization	YES
5445063	28547129	MF	2	contributed to the conception or design of the data collection|contributed to the conception or design of the analysis|participated in the data collection|carried out the data analysis and interpretation|participated in the drafting of the article|carried out the critical revision of the article	participated in the data collection	Performed the experiments	Investigation	YES
5445063	28547129	MF	2	contributed to the conception or design of the data collection|contributed to the conception or design of the analysis|participated in the data collection|carried out the data analysis and interpretation|participated in the drafting of the article|carried out the critical revision of the article	carried out the data analysis and interpretation	Analyzed the data	Formal analysis	YES
5445063	28547129	MF	2	contributed to the conception or design of the data collection|contributed to the conception or design of the analysis|participated in the data collection|carried out the data analysis and interpretation|participated in the drafting of the article|carried out the critical revision of the article	participated in the drafting of the article	Wrote the paper	Writing - Original Draft	YES
5445063	28547129	MF	2	contributed to the conception or design of the data collection|contributed to the conception or design of the analysis|participated in the data collection|carried out the data analysis and interpretation|participated in the drafting of the article|carried out the critical revision of the article	carried out the critical revision of the article	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5445063	28547129	MP	2	contributed to the conception or design of the data collection|contributed to the conception or design of the analysis|carried out the critical revision of the article	contributed to the conception or design of the data collection	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceptualization|Investigation|Resources	YES
5445063	28547129	MP	2	contributed to the conception or design of the data collection|contributed to the conception or design of the analysis|carried out the critical revision of the article	contributed to the conception or design of the analysis	Conceived and designed the experiments	Conceptualization	YES
5445063	28547129	MP	2	contributed to the conception or design of the data collection|contributed to the conception or design of the analysis|carried out the critical revision of the article	carried out the critical revision of the article	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5445063	28547129	PM	2	contributed to the conception or design of the data collection|contributed to the conception or design of the analysis|carried out the critical revision of the article	contributed to the conception or design of the data collection	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceptualization|Investigation|Resources	YES
5445063	28547129	PM	2	contributed to the conception or design of the data collection|contributed to the conception or design of the analysis|carried out the critical revision of the article	contributed to the conception or design of the analysis	Conceived and designed the experiments	Conceptualization	YES
5445063	28547129	PM	2	contributed to the conception or design of the data collection|contributed to the conception or design of the analysis|carried out the critical revision of the article	carried out the critical revision of the article	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5445063	28547129	RG	2	contributed to the conception or design of the data collection|contributed to the conception or design of the analysis|carried out the data analysis and interpretation|participated in the drafting of the article|carried out the critical revision of the article	contributed to the conception or design of the data collection	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceptualization|Investigation|Resources	YES
5445063	28547129	RG	2	contributed to the conception or design of the data collection|contributed to the conception or design of the analysis|carried out the data analysis and interpretation|participated in the drafting of the article|carried out the critical revision of the article	contributed to the conception or design of the analysis	Conceived and designed the experiments	Conceptualization	YES
5445063	28547129	RG	2	contributed to the conception or design of the data collection|contributed to the conception or design of the analysis|carried out the data analysis and interpretation|participated in the drafting of the article|carried out the critical revision of the article	carried out the data analysis and interpretation	Analyzed the data	Formal analysis	YES
5445063	28547129	RG	2	contributed to the conception or design of the data collection|contributed to the conception or design of the analysis|carried out the data analysis and interpretation|participated in the drafting of the article|carried out the critical revision of the article	participated in the drafting of the article	Wrote the paper	Writing - Original Draft	YES
5445063	28547129	RG	2	contributed to the conception or design of the data collection|contributed to the conception or design of the analysis|carried out the data analysis and interpretation|participated in the drafting of the article|carried out the critical revision of the article	carried out the critical revision of the article	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5445063	28547129	RTS	2	contributed to the conception or design of the data collection|contributed to the conception or design of the analysis|carried out the critical revision of the article	contributed to the conception or design of the data collection	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceptualization|Investigation|Resources	YES
5445063	28547129	RTS	2	contributed to the conception or design of the data collection|contributed to the conception or design of the analysis|carried out the critical revision of the article	contributed to the conception or design of the analysis	Conceived and designed the experiments	Conceptualization	YES
5445063	28547129	RTS	2	contributed to the conception or design of the data collection|contributed to the conception or design of the analysis|carried out the critical revision of the article	carried out the critical revision of the article	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4590921	26464844	Vellapallil Raman Kutty	4	which was modified and edited by	which was modified and edited by	Wrote the paper	Writing - Review & Editing	YES
4412635	25919034	ER	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412635	25919034	ER	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412635	25919034	ER	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412635	25919034	JS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412635	25919034	JS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412635	25919034	JW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412635	25919034	JW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412635	25919034	JW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412635	25919034	PT	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412635	25919034	RB	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412635	25919034	RB	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412635	25919034	S. Lee	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412635	25919034	S. Lee	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412635	25919034	S. Legg	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412635	25919034	S. Legg	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412635	25919034	S. Legg	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412635	25919034	S. Lum	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412635	25919034	S. Lum	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412635	25919034	S. Lum	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6070843	30112168	GC	2	were responsible for its drafting and revision	were responsible for its drafting and revision	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6070843	30112168	JQL	2	were responsible for its revision	were responsible for its revision	Wrote the paper	Writing - Review & Editing	YES
6070843	30112168	XL	2	were responsible for writing the manuscript	were responsible for writing the manuscript	Wrote the paper	Writing - Original Draft	YES
6070843	30112168	ZW	2	were responsible for its drafting and revision	were responsible for its drafting and revision	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6070843	30112168	ZWZ	2	were responsible for writing the manuscript	were responsible for writing the manuscript	Wrote the paper	Writing - Original Draft	YES
4589607	26457305	Jin Woo Jang	2	contributed equally to this work	contributed equally to this work	-	-	NO
4589607	26457305	Seung Gyu Yun	2	contributed equally to this work	contributed equally to this work	-	-	NO
5696741	29201037	A-RB	2	was involved in the data analysis and writing	was involved in the data analysis and writing	Analyzed the data|Wrote the paper	Formal analysis	YES
5696741	29201037	AA	2	was involved in the pcoa analysis and interpretation of the results	was involved in the pcoa analysis and interpretation of the results	Analyzed the data	Formal analysis	YES
5696741	29201037	EB	2	was involved in the construction of the libraries, and rt pcr analyses	was involved in the construction of the libraries, and rt pcr analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5696741	29201037	EL	2	was involved in the data analysis and interpretation	was involved in the data analysis and interpretation	Analyzed the data	Formal analysis	YES
5696741	29201037	JN	2	was involved in the project design, data analysis and writing	was involved in the project design, data analysis and writing	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology	YES
5696741	29201037	LG-C	2	was involved in data interpretation and writing the manuscript	was involved in data interpretation and writing the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5696741	29201037	MW	2	were involved in the project design, supervision, data analysis, and writing	were involved in the project design, supervision, data analysis, and writing	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Supervision	YES
5696741	29201037	SD	2	were involved in the project design, supervision, data analysis, and writing	were involved in the project design, supervision, data analysis, and writing	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Supervision	YES
5449315	28560582	AH	2	performed the data analysis	performed the data analysis	Analyzed the data	Formal analysis	YES
5449315	28560582	BI	2	participated in the design of the study and increased the intellectual content	participated in the design of the study and increased the intellectual content	Conceived and designed the experiments	Methodology	YES
5449315	28560582	BS	2	participated in the design of the study and increased the intellectual content	participated in the design of the study and increased the intellectual content	Conceived and designed the experiments	Methodology	YES
5449315	28560582	FV	2	participated in the design of the study, performed data analysis, and helped to draft the manuscript	participated in the design of the study, performed data analysis, and helped to draft the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5449315	28560582	MB	2	participated in the design of the study, performed data analysis, and helped to draft the manuscript	participated in the design of the study, performed data analysis, and helped to draft the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5449315	28560582	ML	2	performed the data analysis	performed the data analysis	Analyzed the data	Formal analysis	YES
5449315	28560582	MU	2	conceived the design of the study, contributed to global data analysis, performed the statistical analysis, and drafted the manuscript	conceived the design of the study, contributed to global data analysis, performed the statistical analysis, and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Methodology|Resources|Writing - Original Draft	YES
5449315	28560582	MZ	2	performed the data analysis	performed the data analysis	Analyzed the data	Formal analysis	YES
5449315	28560582	NA	2	conceived the design of the study, contributed to global data analysis, performed the statistical analysis, and drafted the manuscript	conceived the design of the study, contributed to global data analysis, performed the statistical analysis, and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Methodology|Resources|Writing - Original Draft	YES
5449315	28560582	PB	2	participated in the design of the study and increased the intellectual content	participated in the design of the study and increased the intellectual content	Conceived and designed the experiments	Methodology	YES
5449315	28560582	VW	2	participated in the design of the study and increased the intellectual content	participated in the design of the study and increased the intellectual content	Conceived and designed the experiments	Methodology	YES
5558190	28812536	All authors	2	critically revised and approved the manuscript	critically revised and approved the manuscript	Wrote the paper	Writing - Review & Editing	YES
5558190	28812536	CS	2	implemented the web server	implemented the web server	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5558190	28812536	GB	2	conceived and designed the work and wrote the paper|collected and curated data|implemented the web server|analysed and interpreted data on disease related variations	conceived and designed the work and wrote the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5558190	28812536	GB	2	conceived and designed the work and wrote the paper|collected and curated data|implemented the web server|analysed and interpreted data on disease related variations	collected and curated data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5558190	28812536	GB	2	conceived and designed the work and wrote the paper|collected and curated data|implemented the web server|analysed and interpreted data on disease related variations	implemented the web server	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5558190	28812536	GB	2	conceived and designed the work and wrote the paper|collected and curated data|implemented the web server|analysed and interpreted data on disease related variations	analysed and interpreted data on disease related variations	Analyzed the data	Formal analysis	YES
5558190	28812536	GP	2	implemented the web server	implemented the web server	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5558190	28812536	PLM	2	conceived and designed the work and wrote the paper|analysed and interpreted data on disease related variations	conceived and designed the work and wrote the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5558190	28812536	PLM	2	conceived and designed the work and wrote the paper|analysed and interpreted data on disease related variations	analysed and interpreted data on disease related variations	Analyzed the data	Formal analysis	YES
5558190	28812536	RC	2	conceived and designed the work and wrote the paper|analysed and interpreted data on disease related variations	conceived and designed the work and wrote the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5558190	28812536	RC	2	conceived and designed the work and wrote the paper|analysed and interpreted data on disease related variations	analysed and interpreted data on disease related variations	Analyzed the data	Formal analysis	YES
5558190	28812536	SB	2	ran the net-ge predictions	ran the net-ge predictions	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
1865390	17505543	HL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1865390	17505543	HL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1865390	17505543	HL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1865390	17505543	HL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1865390	17505543	RB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1865390	17505543	RB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1865390	17505543	RB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4589612	26457302	Tongyan Wang	2	contributed equally to this work	contributed equally to this work	-	-	NO
4589612	26457302	Yan Xiao	2	contributed equally to this work	contributed equally to this work	-	-	NO
5697168	29201038	AV	2	conceived the topic|wrote the manuscript|revised several versions of the manuscript	conceived the topic	Conceived and designed the experiments	Conceptualization	YES
5697168	29201038	AV	2	conceived the topic|wrote the manuscript|revised several versions of the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5697168	29201038	AV	2	conceived the topic|wrote the manuscript|revised several versions of the manuscript	revised several versions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5697168	29201038	CE	2	conceived the topic|wrote the manuscript|revised several versions of the manuscript	conceived the topic	Conceived and designed the experiments	Conceptualization	YES
5697168	29201038	CE	2	conceived the topic|wrote the manuscript|revised several versions of the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5697168	29201038	CE	2	conceived the topic|wrote the manuscript|revised several versions of the manuscript	revised several versions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5697168	29201038	JC	2	conceived the topic|wrote the manuscript|revised several versions of the manuscript	conceived the topic	Conceived and designed the experiments	Conceptualization	YES
5697168	29201038	JC	2	conceived the topic|wrote the manuscript|revised several versions of the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5697168	29201038	JC	2	conceived the topic|wrote the manuscript|revised several versions of the manuscript	revised several versions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5697168	29201038	JP-R	2	conceived the topic|wrote the manuscript|revised several versions of the manuscript	conceived the topic	Conceived and designed the experiments	Conceptualization	YES
5697168	29201038	JP-R	2	conceived the topic|wrote the manuscript|revised several versions of the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5697168	29201038	JP-R	2	conceived the topic|wrote the manuscript|revised several versions of the manuscript	revised several versions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5697168	29201038	PC	2	conceived the topic|wrote the manuscript|revised several versions of the manuscript	conceived the topic	Conceived and designed the experiments	Conceptualization	YES
5697168	29201038	PC	2	conceived the topic|wrote the manuscript|revised several versions of the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5697168	29201038	PC	2	conceived the topic|wrote the manuscript|revised several versions of the manuscript	revised several versions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4412636	25919293	CGK	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412636	25919293	CGK	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412636	25919293	CGK	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412636	25919293	CIC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412636	25919293	CIC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412636	25919293	CIC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412636	25919293	CIC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412636	25919293	CIC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412636	25919293	CMW	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412636	25919293	CMW	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412636	25919293	DMS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412636	25919293	DMS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412636	25919293	DMS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412636	25919293	ESM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412636	25919293	ESM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412636	25919293	ESM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412636	25919293	ESM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412636	25919293	ESM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412636	25919293	EZ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412636	25919293	EZ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412636	25919293	EZ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412636	25919293	WJS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412636	25919293	WJS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412636	25919293	WJS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412636	25919293	YD	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412636	25919293	YD	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412636	25919293	YD	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4590923	26464859	All authors	2	contributed to the writing of this paper	contributed to the writing of this paper	Wrote the paper	Writing - Original Draft	YES
4590923	26464859	all authors	2	read and approved the final paper	read and approved the final paper	-	-	NO
1866174	17520015	BE	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1866174	17520015	BE	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1866174	17520015	BE	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1866174	17520015	JM	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1866174	17520015	JM	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1866174	17520015	MA	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1866174	17520015	MA	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1866174	17520015	RH	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1866174	17520015	YZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1866174	17520015	YZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1866174	17520015	YZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1866174	17520015	YZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1866174	17520015	YZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5449352	28560583	AH	2	contributed to the study conception and design|contributed to the project supervision|contributed to the analysis and interpretation of the data|the contributed to critical revision	contributed to the study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5449352	28560583	AH	2	contributed to the study conception and design|contributed to the project supervision|contributed to the analysis and interpretation of the data|the contributed to critical revision	contributed to the project supervision	-	Supervision	YES
5449352	28560583	AH	2	contributed to the study conception and design|contributed to the project supervision|contributed to the analysis and interpretation of the data|the contributed to critical revision	contributed to the analysis and interpretation of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5449352	28560583	AH	2	contributed to the study conception and design|contributed to the project supervision|contributed to the analysis and interpretation of the data|the contributed to critical revision	the contributed to critical revision	Wrote the paper	Writing - Review & Editing	YES
5449352	28560583	BC	2	contributed to the analysis and interpretation of the data|the contributed to critical revision	contributed to the analysis and interpretation of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5449352	28560583	BC	2	contributed to the analysis and interpretation of the data|the contributed to critical revision	the contributed to critical revision	Wrote the paper	Writing - Review & Editing	YES
5449352	28560583	DA	2	contributed to the acquisition of the data|contributed to the analysis and interpretation of the data|contributed to the drafting of the manuscript	contributed to the acquisition of the data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5449352	28560583	DA	2	contributed to the acquisition of the data|contributed to the analysis and interpretation of the data|contributed to the drafting of the manuscript	contributed to the analysis and interpretation of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5449352	28560583	DA	2	contributed to the acquisition of the data|contributed to the analysis and interpretation of the data|contributed to the drafting of the manuscript	contributed to the drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
5449352	28560583	EF	2	contributed to the acquisition of the data|the contributed to critical revision	contributed to the acquisition of the data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5449352	28560583	EF	2	contributed to the acquisition of the data|the contributed to critical revision	the contributed to critical revision	Wrote the paper	Writing - Review & Editing	YES
5449352	28560583	FG	2	contributed to the project supervision	contributed to the project supervision	-	Supervision	YES
5449352	28560583	KV	2	contributed to the study conception and design|contributed to the project supervision|contributed to the analysis and interpretation of the data|the contributed to critical revision	contributed to the study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5449352	28560583	KV	2	contributed to the study conception and design|contributed to the project supervision|contributed to the analysis and interpretation of the data|the contributed to critical revision	contributed to the project supervision	-	Supervision	YES
5449352	28560583	KV	2	contributed to the study conception and design|contributed to the project supervision|contributed to the analysis and interpretation of the data|the contributed to critical revision	contributed to the analysis and interpretation of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5449352	28560583	KV	2	contributed to the study conception and design|contributed to the project supervision|contributed to the analysis and interpretation of the data|the contributed to critical revision	the contributed to critical revision	Wrote the paper	Writing - Review & Editing	YES
5449352	28560583	NP	2	contributed to the study conception and design|contributed to the acquisition of the data|contributed to the analysis and interpretation of the data|contributed to the drafting of the manuscript	contributed to the study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5449352	28560583	NP	2	contributed to the study conception and design|contributed to the acquisition of the data|contributed to the analysis and interpretation of the data|contributed to the drafting of the manuscript	contributed to the acquisition of the data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5449352	28560583	NP	2	contributed to the study conception and design|contributed to the acquisition of the data|contributed to the analysis and interpretation of the data|contributed to the drafting of the manuscript	contributed to the analysis and interpretation of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5449352	28560583	NP	2	contributed to the study conception and design|contributed to the acquisition of the data|contributed to the analysis and interpretation of the data|contributed to the drafting of the manuscript	contributed to the drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
5449352	28560583	SA	2	contributed to the acquisition of the data|contributed to the drafting of the manuscript	contributed to the acquisition of the data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5449352	28560583	SA	2	contributed to the acquisition of the data|contributed to the drafting of the manuscript	contributed to the drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
6178637	30319766	GJ	2	revised the article to add logical reasoning and corrected the literature	revised the article to add logical reasoning and corrected the literature	Wrote the paper	Writing - Review & Editing	YES
6178637	30319766	JG	2	performed medline searches, aided in writing the review article and critiqued the literature	performed medline searches, aided in writing the review article and critiqued the literature	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
6178637	30319766	NLS	2	formulated clinical concepts, reviewed the article, and corrected the references	formulated clinical concepts, reviewed the article, and corrected the references	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
6178637	30319766	OS	2	critiqued and applied logical reasoning to the literature	critiqued and applied logical reasoning to the literature	-	-	NO
6178637	30319766	RK	2	designed, organized, and wrote the review article	designed, organized, and wrote the review article	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6178637	30319766	SAK	2	formulated clinical concepts, reviewed the article, and corrected the references	formulated clinical concepts, reviewed the article, and corrected the references	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
6178637	30319766	WJ	2	critiqued and applied logical reasoning to the literature	critiqued and applied logical reasoning to the literature	-	-	NO
4412639	25919483	WCL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412639	25919483	WCL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412639	25919483	WCL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412639	25919483	WCL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412639	25919483	WCL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5558667	28810832	HL	1	Manuscript preparation	Manuscript preparation	Wrote the paper	Writing - Original Draft	YES
5558667	28810832	XN	1	Manuscript preparation	Manuscript preparation	Wrote the paper	Writing - Original Draft	YES
5558667	28810832	YG	1	Manuscript preparation	Manuscript preparation	Wrote the paper	Writing - Original Draft	YES
5698268	29204149	Evans Allen Grant	2	from tennessee state university and edited the manuscript versions	from tennessee state university and edited the manuscript versions	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5698268	29204149	XW	2	carried out all experiments, prepared tables and figures and wrote the manuscript draft	carried out all experiments, prepared tables and figures and wrote the manuscript draft	Performed the experiments|Wrote the paper	Investigation|Visualization|Writing - Original Draft	YES
1866175	17520016	AC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Suggested the idea for the study	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1866175	17520016	AC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Suggested the idea for the study	Analyzed the data	Analyzed the data	Formal analysis	YES
1866175	17520016	AC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Suggested the idea for the study	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1866175	17520016	AC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Suggested the idea for the study	Suggested the idea for the study	Conceived and designed the experiments	Conceptualization	YES
1866175	17520016	AS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1866175	17520016	ED	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1866175	17520016	ED	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1866175	17520016	ED	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1866175	17520016	JN	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1866175	17520016	JN	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1866175	17520016	PA	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1866175	17520016	PA	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1866175	17520016	RB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1866175	17520016	RB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1866175	17520016	RB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1866175	17520016	TM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1866175	17520016	XH	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1866175	17520016	XH	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
3826330	24288476	George Konstantakopoulos	2	contributed equally to this work	contributed equally to this work	-	-	NO
3826330	24288476	Vasilios G. Masdrakis	2	contributed equally to this work	contributed equally to this work	-	-	NO
6178638	30319762	AM	2	performed the conception or designed the work analysis, or interpretered the data for the work	performed the conception or designed the work analysis, or interpretered the data for the work	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation	YES
6178638	30319762	BY	2	performd the conception or designed the work and revised the final approval of the article	performd the conception or designed the work and revised the final approval of the article	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Review & Editing	YES
6178638	30319762	EM	2	performed the acquisition and analyzed the data for the work and drafted the article	performed the acquisition and analyzed the data for the work and drafted the article	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6178638	30319762	HM	2	performed the conception or designed the interpretation of data for the work	performed the conception or designed the interpretation of data for the work	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation	YES
6178638	30319762	SA	2	collected the data, analyzed the data for the work and drafted the article	collected the data, analyzed the data for the work and drafted the article	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5698279	29204152	AM	2	conceived and wrote the manuscript	conceived and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5698279	29204152	DM	2	conceived and wrote the manuscript	conceived and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5698279	29204152	JK	2	contributed to the data generation and interpretation	contributed to the data generation and interpretation	Analyzed the data	Formal analysis	YES
5698279	29204152	WP	2	contributed to the data generation and interpretation	contributed to the data generation and interpretation	Analyzed the data	Formal analysis	YES
5451375	28567708	JH	2	helped in the data analysis	helped in the data analysis	Analyzed the data	Formal analysis	YES
5451375	28567708	KH	2	is the guarantor of integrity of the entire study, is responsible for the data analysis, statistical analysis, and manuscript writing	is the guarantor of integrity of the entire study, is responsible for the data analysis, statistical analysis, and manuscript writing	Analyzed the data|Wrote the paper	Data curation|Formal analysis|Writing - Original Draft	YES
5451375	28567708	KS	2	carried out the clinical study and data collection	carried out the clinical study and data collection	Performed the experiments	Investigation	YES
5451375	28567708	MT	2	contributed to the study design, literature research, and manuscript editing	contributed to the study design, literature research, and manuscript editing	Conceived and designed the experiments|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
5451375	28567708	TH	2	helped in the data collection and data analysis	helped in the data collection and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5451375	28567708	YA	2	helped in the data collection and data analysis	helped in the data collection and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5451375	28567708	YH	2	helped in the data analysis	helped in the data analysis	Analyzed the data	Formal analysis	YES
5451375	28567708	YT	2	contributed to the manuscript review	contributed to the manuscript review	Wrote the paper	Writing - Review & Editing	YES
5451375	28567708	YY	2	contributed to the manuscript review	contributed to the manuscript review	Wrote the paper	Writing - Review & Editing	YES
4412663	25919632	CHY	PLoS5	Contributed to experimental ideas	Contributed to experimental ideas	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
4412663	25919632	HMX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412663	25919632	HMX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412663	25919632	HMX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412663	25919632	HMX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412663	25919632	HMX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412663	25919632	HWD	PLoS5	Contributed to experimental ideas	Contributed to experimental ideas	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
4412663	25919632	HY	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412663	25919632	HY	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412663	25919632	LL	PLoS5	Contributed to experimental ideas	Contributed to experimental ideas	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
4412663	25919632	QQX	PLoS5	Contributed to experimental ideas	Contributed to experimental ideas	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
4412663	25919632	XLL	PLoS5	Contributed to experimental ideas	Contributed to experimental ideas	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5558719	28810827	All authors	2	read, commented, and approved the final manuscript	read, commented, and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5558719	28810827	BB	2	performed experiments and data analysis|wrote the first draft the manuscript	performed experiments and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5558719	28810827	BB	2	performed experiments and data analysis|wrote the first draft the manuscript	wrote the first draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5558719	28810827	BJM	2	performed experiments and data analysis	performed experiments and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5558719	28810827	HW	2	performed experiments and data analysis	performed experiments and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5558719	28810827	LM	2	performed experiments and data analysis	performed experiments and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5558719	28810827	PAH	2	performed experiments and data analysis	performed experiments and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5558719	28810827	REG	2	performed experiments and data analysis	performed experiments and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5558719	28810827	SC	2	performed experiments and data analysis	performed experiments and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5558719	28810827	TT	2	performed experiments and data analysis	performed experiments and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5558719	28810827	XL	2	performed experiments and data analysis	performed experiments and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5558719	28810827	YL	2	designed the study|performed experiments and data analysis|wrote the first draft the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5558719	28810827	YL	2	designed the study|performed experiments and data analysis|wrote the first draft the manuscript	performed experiments and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5558719	28810827	YL	2	designed the study|performed experiments and data analysis|wrote the first draft the manuscript	wrote the first draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5558719	28810827	all authors	2	significantly contributed to the revision of the manuscript	significantly contributed to the revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
6178639	30319760	JHZ	2	participated in the study design, conceiving and revising of the manuscript	participated in the study design, conceiving and revising of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
6178639	30319760	LH	2	performed the study, conceived and drafted the manuscript, as well as gathered references	performed the study, conceived and drafted the manuscript, as well as gathered references	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
6178639	30319760	PMA	2	participated in study design and revised the manuscript	participated in study design and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
6178639	30319760	RLA	2	participated in study design and revised the manuscript	participated in study design and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
6178639	30319760	WB	2	participated in revising the manucript	participated in revising the manucript	-	-	NO
1866176	17520017	AF	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1866176	17520017	AF	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1866176	17520017	CH	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1866176	17520017	CK	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1866176	17520017	EB	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1866176	17520017	GR	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1866176	17520017	JJ	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1866176	17520017	JJ	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1866176	17520017	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1866176	17520017	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1866176	17520017	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1866176	17520017	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1866176	17520017	MO	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1866176	17520017	SK	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1866176	17520017	SM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1866176	17520017	TC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1866176	17520017	TC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1866176	17520017	TC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1866176	17520017	TC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1866176	17520017	TC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1866176	17520017	YS	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5698287	29204153	CP	PLoS52	performed leaf-level measurements|discussed the results and wrote the manuscript	performed leaf-level measurements	Performed the experiments	Investigation	YES
5698287	29204153	CP	PLoS52	performed leaf-level measurements|discussed the results and wrote the manuscript	discussed the results and wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5698287	29204153	GP	PLoS52	conceived and designed the experiments|analyzed the data|discussed the results and wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5698287	29204153	GP	PLoS52	conceived and designed the experiments|analyzed the data|discussed the results and wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5698287	29204153	GP	PLoS52	conceived and designed the experiments|analyzed the data|discussed the results and wrote the manuscript	discussed the results and wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5698287	29204153	IA	PLoS52	performed the experiments and measurements|analyzed the data|discussed the results and wrote the manuscript	performed the experiments and measurements	Performed the experiments	Investigation	YES
5698287	29204153	IA	PLoS52	performed the experiments and measurements|analyzed the data|discussed the results and wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5698287	29204153	IA	PLoS52	performed the experiments and measurements|analyzed the data|discussed the results and wrote the manuscript	discussed the results and wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5698287	29204153	LA	PLoS52	conceived and designed the experiments|discussed the results and wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5698287	29204153	LA	PLoS52	conceived and designed the experiments|discussed the results and wrote the manuscript	discussed the results and wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5698287	29204153	LV	PLoS52	performed the experiments and measurements|analyzed the data|discussed the results and wrote the manuscript	performed the experiments and measurements	Performed the experiments	Investigation	YES
5698287	29204153	LV	PLoS52	performed the experiments and measurements|analyzed the data|discussed the results and wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5698287	29204153	LV	PLoS52	performed the experiments and measurements|analyzed the data|discussed the results and wrote the manuscript	discussed the results and wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5457373	28577295	JS-H	2	performed the histological analysis	performed the histological analysis	Performed the experiments	Investigation	YES
5457373	28577295	PH	2	provided patient care and analyzed the patient data|wrote the manuscript	provided patient care and analyzed the patient data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5457373	28577295	PH	2	provided patient care and analyzed the patient data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5457373	28577295	SH	2	provided patient care and analyzed the patient data	provided patient care and analyzed the patient data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5457373	28577295	SK	2	performed the histological analysis	performed the histological analysis	Performed the experiments	Investigation	YES
5457373	28577295	UK	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4412664	25919288	DZ	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412664	25919288	DZ	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412664	25919288	JZ	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412664	25919288	JZ	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412664	25919288	KC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4412664	25919288	KL	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4412664	25919288	MM	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412664	25919288	MM	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412664	25919288	PL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4412664	25919288	QB	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4412664	25919288	QX	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4412664	25919288	QZ	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4412664	25919288	TZ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412664	25919288	XL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1866177	17505544	BK	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1866177	17505544	BK	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1866177	17505544	BK	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1866177	17505544	CB	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1866177	17505544	EF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1866177	17505544	EF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1866177	17505544	EF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1866177	17505544	FK	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1866177	17505544	FK	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1866177	17505544	JA	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1866177	17505544	JA	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1866177	17505544	JA	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1866177	17505544	KD	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1866177	17505544	KD	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1866177	17505544	KN	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1866177	17505544	KN	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1866177	17505544	KN	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1866177	17505544	NM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1866177	17505544	RK	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1866177	17505544	RK	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1866177	17505544	RK	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1866177	17505544	SN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1866177	17505544	SN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1866177	17505544	SN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1866177	17505544	SN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1866177	17505544	TR	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1866177	17505544	TR	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1866177	17505544	XL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
6178640	30319763	All the authors	2	participated in the laboratory stages of the study	participated in the laboratory stages of the study	Performed the experiments	Investigation	YES
4416096	25977875	AG	2	carried out the experiment|analyzed the data and contributed for the statistical analysis	carried out the experiment	Performed the experiments	Investigation	YES
4416096	25977875	AG	2	carried out the experiment|analyzed the data and contributed for the statistical analysis	analyzed the data and contributed for the statistical analysis	Analyzed the data	Formal analysis	YES
4416096	25977875	AH	2	have designed the work|carried out the experiment|analyzed the data and contributed for the statistical analysis|wrote the manuscript and reviewed the manuscript critically	have designed the work	Conceived and designed the experiments	-	YES
4416096	25977875	AH	2	have designed the work|carried out the experiment|analyzed the data and contributed for the statistical analysis|wrote the manuscript and reviewed the manuscript critically	carried out the experiment	Performed the experiments	Investigation	YES
4416096	25977875	AH	2	have designed the work|carried out the experiment|analyzed the data and contributed for the statistical analysis|wrote the manuscript and reviewed the manuscript critically	analyzed the data and contributed for the statistical analysis	Analyzed the data	Formal analysis	YES
4416096	25977875	AH	2	have designed the work|carried out the experiment|analyzed the data and contributed for the statistical analysis|wrote the manuscript and reviewed the manuscript critically	wrote the manuscript and reviewed the manuscript critically	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4416096	25977875	All the authors	2	have read the article and approved the final manuscript	have read the article and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4416096	25977875	MFL	2	have designed the work|analyzed the data and contributed for the statistical analysis|wrote the manuscript and reviewed the manuscript critically	have designed the work	Conceived and designed the experiments	-	YES
4416096	25977875	MFL	2	have designed the work|analyzed the data and contributed for the statistical analysis|wrote the manuscript and reviewed the manuscript critically	analyzed the data and contributed for the statistical analysis	Analyzed the data	Formal analysis	YES
4416096	25977875	MFL	2	have designed the work|analyzed the data and contributed for the statistical analysis|wrote the manuscript and reviewed the manuscript critically	wrote the manuscript and reviewed the manuscript critically	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4416096	25977875	MK	2	have designed the work|analyzed the data and contributed for the statistical analysis|wrote the manuscript and reviewed the manuscript critically	have designed the work	Conceived and designed the experiments	-	YES
4416096	25977875	MK	2	have designed the work|analyzed the data and contributed for the statistical analysis|wrote the manuscript and reviewed the manuscript critically	analyzed the data and contributed for the statistical analysis	Analyzed the data	Formal analysis	YES
4416096	25977875	MK	2	have designed the work|analyzed the data and contributed for the statistical analysis|wrote the manuscript and reviewed the manuscript critically	wrote the manuscript and reviewed the manuscript critically	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4416096	25977875	PGYSYS	2	jacobs university bremen	jacobs university bremen	-	-	NO
4412665	25919305	HP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412665	25919305	HP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412665	25919305	HP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412665	25919305	HP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412665	25919305	HP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412665	25919305	LV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412665	25919305	LV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412665	25919305	LV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412665	25919305	LV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412665	25919305	PR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412665	25919305	PR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412665	25919305	PR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412665	25919305	PR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412665	25919305	PR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412665	25919305	SS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412665	25919305	SS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412665	25919305	SS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5558724	28810831	BJH	2	supervised this project	supervised this project	-	Supervision	YES
5558724	28810831	BR	2	algorithm, analysed the sequence data and drafted the manuscript	algorithm, analysed the sequence data and drafted the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Software|Writing - Original Draft	YES
5558724	28810831	IMM	2	provided help with the processing of the whole genome sequence data	provided help with the processing of the whole genome sequence data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Investigation|Resources	YES
5558724	28810831	JEP	2	gave support to genomic prediction on heat tolerance data	gave support to genomic prediction on heat tolerance data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5558724	28810831	MEG	2	contributed the valuable ideas about the application of hybrid scheme to the whole genome sequence data	contributed the valuable ideas about the application of hybrid scheme to the whole genome sequence data	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceptualization|Investigation|Resources	YES
5558724	28810831	Y-PPC	2	supervised this project	supervised this project	-	Supervision	YES
5698777	29204148	All authors	2	listed have made a substantial, direct and intellectual contribution to the work, and approved it for publication	listed have made a substantial, direct and intellectual contribution to the work, and approved it for publication	-	-	NO
5459776	28585219	All authors	2	participated in the study planning, data analysis, and drafting of the manuscript and approved the final version	participated in the study planning, data analysis, and drafting of the manuscript and approved the final version	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
6178641	30319764	M. Critical	2	revisions of the manuscript were made by all authors	revisions of the manuscript were made by all authors	Wrote the paper	Writing - Review & Editing	YES
1866178	17520021	CZ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1866178	17520021	FP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1866178	17520021	GS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1866178	17520021	HX	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1866178	17520021	HX	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1866178	17520021	HX	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1866178	17520021	HX	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1866178	17520021	JC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1866178	17520021	KT	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1866178	17520021	MH	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1866178	17520021	SN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1866178	17520021	SN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1866178	17520021	SN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1866178	17520021	ST	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1866178	17520021	VN	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1866178	17520021	WL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1866178	17520021	WL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1866178	17520021	WL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1866178	17520021	WL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1866178	17520021	XX	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1866178	17520021	ZX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1866178	17520021	ZX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1866178	17520021	ZX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1866178	17520021	ZX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1866178	17520021	ZY	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
6178642	30319765	IR	2	revised the article to add logical reasoning and corrected the literature	revised the article to add logical reasoning and corrected the literature	Wrote the paper	Writing - Review & Editing	YES
6178642	30319765	JG	2	critiqued and applied logical reasoning to the literature	critiqued and applied logical reasoning to the literature	-	-	NO
6178642	30319765	NLS	2	performed medline searches, aided in writing the review article and critiqued the literature	performed medline searches, aided in writing the review article and critiqued the literature	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
6178642	30319765	OS	2	designed, organized, and wrote the review article	designed, organized, and wrote the review article	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6178642	30319765	SAK	2	formulated clinical concepts, reviewed the article, and corrected the reference	formulated clinical concepts, reviewed the article, and corrected the reference	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
6178642	30319765	WJ	2	critiqued and applied logical reasoning to the literature	critiqued and applied logical reasoning to the literature	-	-	NO
5558757	28810905	AMM	2	designed the study, analyzed the data, implemented the software and wrote the manuscript	designed the study, analyzed the data, implemented the software and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Software|Writing - Original Draft	YES
5558757	28810905	MK	2	performed the data curation, validation and, contributed to the discussion	performed the data curation, validation and, contributed to the discussion	Performed the experiments|Analyzed the data	Data curation|Validation	YES
5558757	28810905	VBB	2	conceptualized and designed the study, contributed to the discussion, and reviewed/edited the manuscript	conceptualized and designed the study, contributed to the discussion, and reviewed/edited the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
5698779	29204147	AK	2	collected data for section 1 and edited all sections after completing	collected data for section 1 and edited all sections after completing	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5698779	29204147	LZ	2	collected data for section 1 and edited all sections after completing	collected data for section 1 and edited all sections after completing	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5698779	29204147	PL	2	coordinated the all parts of the review and made final corrections and revisions	coordinated the all parts of the review and made final corrections and revisions	Wrote the paper	Project administration|Writing - Review & Editing	YES
5698779	29204147	YS	2	generated an idea and wrote first draft of the manuscript	generated an idea and wrote first draft of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
4427575	25992304	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4427575	25992304	KK	2	participated in the experimental design and revised the manuscript	participated in the experimental design and revised the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
4427575	25992304	MU	2	contributed to the experimental design and revised the manuscript critically	contributed to the experimental design and revised the manuscript critically	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
4427575	25992304	TS	2	designed and carried out the experiments, and drafted the manuscript	designed and carried out the experiments, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
4412667	25919136	CC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412667	25919136	CW	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412667	25919136	HC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412667	25919136	HD	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412667	25919136	HZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4412667	25919136	JH	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412667	25919136	JL	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412667	25919136	JL	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412667	25919136	JLL	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4412667	25919136	LL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412667	25919136	WG	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412667	25919136	WL	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412667	25919136	WL	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412667	25919136	WL	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412667	25919136	XDZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4412667	25919136	XZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4412667	25919136	YJS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412667	25919136	YPS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412667	25919136	YTT	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412667	25919136	YW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412667	25919136	YW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412667	25919136	YW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412667	25919136	YX	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412667	25919136	YX	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6178643	30319769	HMRK	2	concepted and designed the study, collected the data, searched the literature, wrote-up, reviewed and edited the manuscript	concepted and designed the study, collected the data, searched the literature, wrote-up, reviewed and edited the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
6178643	30319769	MK	2	designed, collected the data, and wrote-up the manuscript	designed, collected the data, and wrote-up the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5478550	28634836	AT	PLoS52	designed the study and wrote the protocol|analyzed the data	designed the study and wrote the protocol	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5478550	28634836	AT	PLoS52	designed the study and wrote the protocol|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5478550	28634836	CH	PLoS52	designed the study and wrote the protocol	designed the study and wrote the protocol	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5478550	28634836	PS	PLoS52	designed the study and wrote the protocol|conducted the pet experiment|analyzed the data	designed the study and wrote the protocol	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5478550	28634836	PS	PLoS52	designed the study and wrote the protocol|conducted the pet experiment|analyzed the data	conducted the pet experiment	Performed the experiments	Investigation	YES
5478550	28634836	PS	PLoS52	designed the study and wrote the protocol|conducted the pet experiment|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5478550	28634836	RA	PLoS52	analyzed the data|wrote the first draft of the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5478550	28634836	RA	PLoS52	analyzed the data|wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
5478550	28634836	RSM	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5478550	28634836	SN	PLoS52	conducted the pet experiment	conducted the pet experiment	Performed the experiments	Investigation	YES
1866179	17505545	AR	PLoS5	Performed the experiments|Discussed data analysis and provided assistance with writing the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
1866179	17505545	AR	PLoS5	Performed the experiments|Discussed data analysis and provided assistance with writing the manuscript	Discussed data analysis and provided assistance with writing the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
1866179	17505545	JG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1866179	17505545	TW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1866179	17505545	TW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1866179	17505545	TW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1866179	17505545	TW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6178644	30319767	CSZ	2	was responsible for writing the manuscript	was responsible for writing the manuscript	Wrote the paper	Writing - Original Draft	YES
6178644	30319767	GC	2	were responsible for its drafting and revision	were responsible for its drafting and revision	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6178644	30319767	HL	2	was responsible for its revision	was responsible for its revision	Wrote the paper	Writing - Review & Editing	YES
6178644	30319767	ZW	2	were responsible for its drafting and revision	were responsible for its drafting and revision	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5698875	29204151	ES	2	collected plant materials	collected plant materials	Performed the experiments	Investigation	YES
5698875	29204151	H-JS	2	conducted the experiments and analyzed the data	conducted the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5698875	29204151	HP	2	commented on the research	commented on the research	-	-	NO
5698875	29204151	JIL	2	collected plant materials	collected plant materials	Performed the experiments	Investigation	YES
5698875	29204151	JK	2	collected plant materials	collected plant materials	Performed the experiments	Investigation	YES
5698875	29204151	JP	2	collected plant materials	collected plant materials	Performed the experiments	Investigation	YES
5698875	29204151	JRL	2	commented on the research	commented on the research	-	-	NO
5698875	29204151	MA	2	collected plant materials	collected plant materials	Performed the experiments	Investigation	YES
5698875	29204151	S-KK	2	conducted the experiments and analyzed the data	conducted the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5698875	29204151	SC	2	collected plant materials	collected plant materials	Performed the experiments	Investigation	YES
5698875	29204151	SM	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5698875	29204151	SSK	2	conducted the experiments and analyzed the data	conducted the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5698875	29204151	SWK	2	commented on the research	commented on the research	-	-	NO
5698875	29204151	SY	2	designed the study|conducted the experiments and analyzed the data|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5698875	29204151	SY	2	designed the study|conducted the experiments and analyzed the data|wrote the manuscript	conducted the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5698875	29204151	SY	2	designed the study|conducted the experiments and analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5698875	29204151	WJ	2	commented on the research	commented on the research	-	-	NO
5698875	29204151	YL	2	commented on the research	commented on the research	-	-	NO
555941	15740615	AKM	2	performed rt pcr and cloning	performed rt pcr and cloning	Performed the experiments	Investigation	YES
555941	15740615	CK	2	participated in the design of the study and the assembly of genomic sequences	participated in the design of the study and the assembly of genomic sequences	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
555941	15740615	FR	2	conceived the study, performed the assembly of genomic sequences and the sequence alignments and drafted the manuscript	conceived the study, performed the assembly of genomic sequences and the sequence alignments and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
555941	15740615	HU	2	carried out the gene expression studies	carried out the gene expression studies	Performed the experiments	Investigation	YES
555941	15740615	TM	2	carried out the gene expression studies	carried out the gene expression studies	Performed the experiments	Investigation	YES
555941	15740615	TQPU	2	participated in the design of the study and the assembly of genomic sequences	participated in the design of the study and the assembly of genomic sequences	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4412668	25919300	AK	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4412668	25919300	AK	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4412668	25919300	AK	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412668	25919300	K. Sugie	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Responsible for the overall study design, participated in the organization, planning, and coordination of the study, and wrote the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412668	25919300	K. Sugie	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Responsible for the overall study design, participated in the organization, planning, and coordination of the study, and wrote the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4412668	25919300	K. Sugie	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Responsible for the overall study design, participated in the organization, planning, and coordination of the study, and wrote the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4412668	25919300	K. Sugie	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Responsible for the overall study design, participated in the organization, planning, and coordination of the study, and wrote the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412668	25919300	K. Sugie	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Responsible for the overall study design, participated in the organization, planning, and coordination of the study, and wrote the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412668	25919300	K. Sugie	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Responsible for the overall study design, participated in the organization, planning, and coordination of the study, and wrote the manuscript	Responsible for the overall study design, participated in the organization, planning, and coordination of the study, and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft	YES
4412668	25919300	KK	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4412668	25919300	M. Sugie	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Responsible for the overall study design, participated in the organization, planning, and coordination of the study, and wrote the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412668	25919300	M. Sugie	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Responsible for the overall study design, participated in the organization, planning, and coordination of the study, and wrote the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4412668	25919300	M. Sugie	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Responsible for the overall study design, participated in the organization, planning, and coordination of the study, and wrote the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4412668	25919300	M. Sugie	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Responsible for the overall study design, participated in the organization, planning, and coordination of the study, and wrote the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412668	25919300	M. Sugie	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Responsible for the overall study design, participated in the organization, planning, and coordination of the study, and wrote the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412668	25919300	M. Sugie	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Responsible for the overall study design, participated in the organization, planning, and coordination of the study, and wrote the manuscript	Responsible for the overall study design, participated in the organization, planning, and coordination of the study, and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft	YES
4412668	25919300	SU	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4412668	25919300	TI	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4412668	25919300	TI	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4412668	25919300	TI	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412668	25919300	TT	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4412668	25919300	YT	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4412668	25919300	YT	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4412668	25919300	YT	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4437994	25995981	All authors	2	revised and approved the manuscript	revised and approved the manuscript	Wrote the paper	Writing - Review & Editing	YES
4437994	25995981	BR	2	supervised the synthesized the tilivalline under	supervised the synthesized the tilivalline under	Performed the experiments	Investigation|Supervision	YES
4437994	25995981	BV	2	supervised the work of tdr and ev	supervised the work of tdr and ev	-	Supervision	YES
4437994	25995981	CG	2	advised on and performed the peptide analysis	advised on and performed the peptide analysis	Performed the experiments	Investigation	YES
4437994	25995981	CVS	2	supervised the synthesized the tilivalline under	supervised the synthesized the tilivalline under	Performed the experiments	Investigation|Supervision	YES
4437994	25995981	EV	2	conducted all experiments	conducted all experiments	Performed the experiments	Investigation	YES
4437994	25995981	IV	2	advised on and performed the peptide analysis	advised on and performed the peptide analysis	Performed the experiments	Investigation	YES
4437994	25995981	Karlien Van Wesemael	2	for confirming the used cell line to be mycoplasma free	for confirming the used cell line to be mycoplasma free	Performed the experiments	Investigation	YES
4437994	25995981	LMDC	2	synthesized the tilivalline under	synthesized the tilivalline under	Performed the experiments	Investigation	YES
4437994	25995981	MB	2	supervised the work of tdr and ev	supervised the work of tdr and ev	-	Supervision	YES
4437994	25995981	TDR	2	conducted all experiments|performed the data analysis, statistical analysis and drafted the manuscript	conducted all experiments	Performed the experiments	Investigation	YES
4437994	25995981	TDR	2	conducted all experiments|performed the data analysis, statistical analysis and drafted the manuscript	performed the data analysis, statistical analysis and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4437994	25995981	TVDW	2	supervised the work of tdr and ev	supervised the work of tdr and ev	-	Supervision	YES
1866180	17520023	AF	PLoS5	Contributed reagents/materials/analysis tools|Participated in the acquisition and interpretation of data, and revised the paper critically for important intellectual content	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1866180	17520023	AF	PLoS5	Contributed reagents/materials/analysis tools|Participated in the acquisition and interpretation of data, and revised the paper critically for important intellectual content	Participated in the acquisition and interpretation of data, and revised the paper critically for important intellectual content	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
1866180	17520023	AV	PLoS5	Contributed reagents/materials/analysis tools|Participated in the acquisition and interpretation of data, and revised the paper critically for important intellectual content	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1866180	17520023	AV	PLoS5	Contributed reagents/materials/analysis tools|Participated in the acquisition and interpretation of data, and revised the paper critically for important intellectual content	Participated in the acquisition and interpretation of data, and revised the paper critically for important intellectual content	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
1866180	17520023	CT	PLoS5	Contributed reagents/materials/analysis tools|Participated in the acquisition and interpretation of data, and revised the paper critically for important intellectual content	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1866180	17520023	CT	PLoS5	Contributed reagents/materials/analysis tools|Participated in the acquisition and interpretation of data, and revised the paper critically for important intellectual content	Participated in the acquisition and interpretation of data, and revised the paper critically for important intellectual content	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
1866180	17520023	FC	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1866180	17520023	FC	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1866180	17520023	LD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1866180	17520023	LD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1866180	17520023	LD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1866180	17520023	SA	PLoS5	Contributed reagents/materials/analysis tools|Participated in the acquisition and interpretation of data, and revised the paper critically for important intellectual content	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1866180	17520023	SA	PLoS5	Contributed reagents/materials/analysis tools|Participated in the acquisition and interpretation of data, and revised the paper critically for important intellectual content	Participated in the acquisition and interpretation of data, and revised the paper critically for important intellectual content	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
5479776	28639254	HD	2	contributed to the study design, preparation of the study, analyzing of the data	contributed to the study design, preparation of the study, analyzing of the data	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Methodology|Resources	YES
5479776	28639254	KM	2	contributed to phantom data collection	contributed to phantom data collection	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5479776	28639254	KS	2	contributed to phantom data collection	contributed to phantom data collection	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5479776	28639254	MJ	2	contributed to the study design and critical revision of the manuscript	contributed to the study design and critical revision of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5479776	28639254	NY	2	contributed to phantom data collection	contributed to phantom data collection	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5479776	28639254	RT	2	contributed to phantom data collection	contributed to phantom data collection	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5479776	28639254	TI	2	contributed to phantom data collection	contributed to phantom data collection	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5479776	28639254	TN	2	contributed to the study design, analyzing of the data, drafting of the manuscript, and critical revision of the manuscript	contributed to the study design, analyzing of the data, drafting of the manuscript, and critical revision of the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5479776	28639254	TO	2	contributed to phantom data collection	contributed to phantom data collection	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5479776	28639254	YO	2	contributed to phantom data collection	contributed to phantom data collection	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5479776	28639254	YY	2	contributed to phantom data collection	contributed to phantom data collection	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
6178645	30319761	GS	2	designed this study	designed this study	Conceived and designed the experiments	Methodology	YES
6178645	30319761	HJ	2	conducted detections|conducted statistical analysis	conducted detections	Performed the experiments	Investigation	YES
6178645	30319761	HJ	2	conducted detections|conducted statistical analysis	conducted statistical analysis	Analyzed the data	Formal analysis	YES
6178645	30319761	HQ	2	established the animal model	established the animal model	Performed the experiments	Methodology	YES
6178645	30319761	SJ	2	established the animal model|conducted detections	established the animal model	Performed the experiments	Methodology	YES
6178645	30319761	SJ	2	established the animal model|conducted detections	conducted detections	Performed the experiments	Investigation	YES
6178645	30319761	SQ	2	designed this study	designed this study	Conceived and designed the experiments	Methodology	YES
6178645	30319761	YS	2	designed this study|conducted detections|conducted statistical analysis	designed this study	Conceived and designed the experiments	Methodology	YES
6178645	30319761	YS	2	designed this study|conducted detections|conducted statistical analysis	conducted detections	Performed the experiments	Investigation	YES
6178645	30319761	YS	2	designed this study|conducted detections|conducted statistical analysis	conducted statistical analysis	Analyzed the data	Formal analysis	YES
4590932	26464867	Ayman El-Garf	2	was responsible for data collection, revision of the statistical analysis of the results, and revision of the paper	was responsible for data collection, revision of the statistical analysis of the results, and revision of the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
4590932	26464867	Hala Mohammed Lotfy	2	was responsible for supervision of data collection, revision of the statistical analysis of the results, and revision of the paper	was responsible for supervision of data collection, revision of the statistical analysis of the results, and revision of the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Supervision|Writing - Review & Editing	YES
4590932	26464867	Huda Marzouk	2	carried out data collection, revision of the statistical analysis of the results, writing and revising the results, writing the paper, and corresponding for publication	carried out data collection, revision of the statistical analysis of the results, writing and revising the results, writing the paper, and corresponding for publication	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
4590932	26464867	Laila Ahmed Rashed	2	was in charge of performance and supervision of laboratory investigations and revision of the paper	was in charge of performance and supervision of laboratory investigations and revision of the paper	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Review & Editing	YES
4590932	26464867	Yomna Mohammed Farag	2	carried out data collection, revision of the statistical analysis of the results, and revision of the paper	carried out data collection, revision of the statistical analysis of the results, and revision of the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
555942	15757509	MR	2	participated in the data analysis and in writing the manuscript	participated in the data analysis and in writing the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
555942	15757509	MS	2	designed the study, performed the sequence analysis, and participated in the data analysis and in writing the manuscript	designed the study, performed the sequence analysis, and participated in the data analysis and in writing the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4412669	25918842	ES	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412669	25918842	ES	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412669	25918842	ES	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412669	25918842	GS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412669	25918842	GS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412669	25918842	GS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412669	25918842	GS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412669	25918842	MF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412669	25918842	MF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412669	25918842	MF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412669	25918842	MF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412669	25918842	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412669	25918842	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412669	25918842	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5699443	29204150	All authors	2	made substantial contributions to conception and design of the experiment	made substantial contributions to conception and design of the experiment	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
5699443	29204150	GD	2	participate in revising the manuscript critically	participate in revising the manuscript critically	Wrote the paper	Writing - Review & Editing	YES
5699443	29204150	H-PK	2	participate in revising the manuscript critically	participate in revising the manuscript critically	Wrote the paper	Writing - Review & Editing	YES
5699443	29204150	NRS	2	performed the experiment including phenotypic and molecular analyses|analyzed and interpreted the data and wrote the manuscript	performed the experiment including phenotypic and molecular analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5699443	29204150	NRS	2	performed the experiment including phenotypic and molecular analyses|analyzed and interpreted the data and wrote the manuscript	analyzed and interpreted the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5699443	29204150	SW	2	analyzed and interpreted the data and wrote the manuscript	analyzed and interpreted the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4592895	26484352	Bong Soo Cha	2	were responsible for the critical revision of the paper	were responsible for the critical revision of the paper	Wrote the paper	Writing - Review & Editing	YES
4592895	26484352	Byung-Wan Lee	2	carried out data analysis and interpretation|were responsible for the drafting of the paper	carried out data analysis and interpretation	Analyzed the data	Formal analysis	YES
4592895	26484352	Byung-Wan Lee	2	carried out data analysis and interpretation|were responsible for the drafting of the paper	were responsible for the drafting of the paper	Wrote the paper	Writing - Original Draft	YES
4592895	26484352	Eun Seok Kang	2	were responsible for the critical revision of the paper	were responsible for the critical revision of the paper	Wrote the paper	Writing - Review & Editing	YES
4592895	26484352	Hyun Chul Lee	2	carried out data analysis and interpretation|were responsible for the critical revision of the paper	carried out data analysis and interpretation	Analyzed the data	Formal analysis	YES
4592895	26484352	Hyun Chul Lee	2	carried out data analysis and interpretation|were responsible for the critical revision of the paper	were responsible for the critical revision of the paper	Wrote the paper	Writing - Review & Editing	YES
4592895	26484352	Kwang Joon Kim	2	were responsible for the critical revision of the paper|were responsible for the statistics	were responsible for the critical revision of the paper	Wrote the paper	Writing - Review & Editing	YES
4592895	26484352	Kwang Joon Kim	2	were responsible for the critical revision of the paper|were responsible for the statistics	were responsible for the statistics	Analyzed the data	Formal analysis	YES
4592895	26484352	So Ra Kim	2	carried out data analysis and interpretation	carried out data analysis and interpretation	Analyzed the data	Formal analysis	YES
4441645	26020015	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4441645	26020015	DCV	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
4441645	26020015	ESM	2	conceived experiments|helped to draft the manuscript|analyzed data	conceived experiments	Conceived and designed the experiments	Conceptualization	YES
4441645	26020015	ESM	2	conceived experiments|helped to draft the manuscript|analyzed data	helped to draft the manuscript	Wrote the paper	Writing - Original Draft	YES
4441645	26020015	ESM	2	conceived experiments|helped to draft the manuscript|analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
4441645	26020015	IAD	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
4441645	26020015	MM	2	conceived experiments|performed the statistical analysis|analyzed data	conceived experiments	Conceived and designed the experiments	Conceptualization	YES
4441645	26020015	MM	2	conceived experiments|performed the statistical analysis|analyzed data	performed the statistical analysis	Analyzed the data	Formal analysis	YES
4441645	26020015	MM	2	conceived experiments|performed the statistical analysis|analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
4441645	26020015	PC	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
1866181	17520024	AH	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1866181	17520024	AH	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1866181	17520024	KB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1866181	17520024	KB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1866181	17520024	KB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1866181	17520024	KB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1866181	17520024	KF	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1866181	17520024	MT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1866181	17520024	MT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1866181	17520024	MT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1866181	17520024	MT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1866181	17520024	MT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1866181	17520024	SM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1866181	17520024	SM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1866181	17520024	SM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1866181	17520024	SM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
555945	15757516	A.J.E.	2	initiated and carried out the molecular genetic studies, drafted the manuscript and approved the final manuscript	initiated and carried out the molecular genetic studies, drafted the manuscript and approved the final manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
6352566	30713673	EFF	1	Conception and design of the work, definition of intellectual content, literature research, data acquisition, data analysis, manuscript preparation, manuscript editing, and manuscript review	Conception and design of the work, definition of intellectual content, literature research, data acquisition, data analysis, manuscript preparation, manuscript editing, and manuscript review	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
6352566	30713673	PGH	1	Conception and design of the work, definition of intellectual content, literature research, data acquisition, data analysis, manuscript preparation, manuscript editing, and manuscript review	Conception and design of the work, definition of intellectual content, literature research, data acquisition, data analysis, manuscript preparation, manuscript editing, and manuscript review	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5503853	28695424	AK	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5503853	28695424	AL	2	designed the study|analysed scans	designed the study	Conceived and designed the experiments	Methodology	YES
5503853	28695424	AL	2	designed the study|analysed scans	analysed scans	-	-	NO
5503853	28695424	All authors	2	contributed to the drafting of the manuscript, and all authors read and approved the final manuscript	contributed to the drafting of the manuscript, and all authors read and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5503853	28695424	BV	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5503853	28695424	KO	2	designed the study|included patients	designed the study	Conceived and designed the experiments	Methodology	YES
5503853	28695424	KO	2	designed the study|included patients	included patients	-	-	NO
5503853	28695424	MA	2	analysed data	analysed data	Analyzed the data	Formal analysis	YES
5503853	28695424	MBM	2	designed the study|included patients|analysed data	designed the study	Conceived and designed the experiments	Methodology	YES
5503853	28695424	MBM	2	designed the study|included patients|analysed data	included patients	-	-	NO
5503853	28695424	MBM	2	designed the study|included patients|analysed data	analysed data	Analyzed the data	Formal analysis	YES
5503853	28695424	TA	2	analysed scans	analysed scans	-	-	NO
4412670	25919692	AMM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412670	25919692	AMM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412670	25919692	AMM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412670	25919692	LG	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412670	25919692	MCC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4412670	25919692	MNV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412670	25919692	MNV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412670	25919692	MNV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412670	25919692	MNV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412670	25919692	MNV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5701616	29209337	CL	PLoS5	Designed research|Wrote the manuscript	Designed research	Conceived and designed the experiments	Methodology	YES
5701616	29209337	CL	PLoS5	Designed research|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5701616	29209337	GH	PLoS5	Designed research|Performed research|Analyzed the data|Wrote the manuscript	Designed research	Conceived and designed the experiments	Methodology	YES
5701616	29209337	GH	PLoS5	Designed research|Performed research|Analyzed the data|Wrote the manuscript	Performed research	Performed the experiments	Investigation	YES
5701616	29209337	GH	PLoS5	Designed research|Performed research|Analyzed the data|Wrote the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
5701616	29209337	GH	PLoS5	Designed research|Performed research|Analyzed the data|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5701616	29209337	KJF	PLoS5	Analyzed the data|Wrote the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
5701616	29209337	KJF	PLoS5	Analyzed the data|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5701616	29209337	MD	PLoS5	Designed research|Analyzed the data|Wrote the manuscript	Designed research	Conceived and designed the experiments	Methodology	YES
5701616	29209337	MD	PLoS5	Designed research|Analyzed the data|Wrote the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
5701616	29209337	MD	PLoS5	Designed research|Analyzed the data|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5701616	29209337	PU	PLoS5	Designed research|Wrote the manuscript	Designed research	Conceived and designed the experiments	Methodology	YES
5701616	29209337	PU	PLoS5	Designed research|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5701616	29209337	SH	PLoS5	Designed research|Wrote the manuscript	Designed research	Conceived and designed the experiments	Methodology	YES
5701616	29209337	SH	PLoS5	Designed research|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4441647	26020016	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4441647	26020016	HM	2	performed most of the mass measurement|performed most of the statistical analyses|designed the study and drafted the manuscript	performed most of the mass measurement	Performed the experiments	Investigation	YES
4441647	26020016	HM	2	performed most of the mass measurement|performed most of the statistical analyses|designed the study and drafted the manuscript	performed most of the statistical analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4441647	26020016	HM	2	performed most of the mass measurement|performed most of the statistical analyses|designed the study and drafted the manuscript	designed the study and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4441647	26020016	KE	2	generated the strains used|performed most of the mass measurement|performed most of the statistical analyses|designed the study and drafted the manuscript	generated the strains used	Performed the experiments	Investigation	YES
4441647	26020016	KE	2	generated the strains used|performed most of the mass measurement|performed most of the statistical analyses|designed the study and drafted the manuscript	performed most of the mass measurement	Performed the experiments	Investigation	YES
4441647	26020016	KE	2	generated the strains used|performed most of the mass measurement|performed most of the statistical analyses|designed the study and drafted the manuscript	performed most of the statistical analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4441647	26020016	KE	2	generated the strains used|performed most of the mass measurement|performed most of the statistical analyses|designed the study and drafted the manuscript	designed the study and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4441647	26020016	KK	2	designed the study and drafted the manuscript	designed the study and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4441647	26020016	MU	2	designed the study and drafted the manuscript	designed the study and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4441647	26020016	SA	2	generated the strains used|performed most of the mass measurement|performed most of the statistical analyses|designed the study and drafted the manuscript	generated the strains used	Performed the experiments	Investigation	YES
4441647	26020016	SA	2	generated the strains used|performed most of the mass measurement|performed most of the statistical analyses|designed the study and drafted the manuscript	performed most of the mass measurement	Performed the experiments	Investigation	YES
4441647	26020016	SA	2	generated the strains used|performed most of the mass measurement|performed most of the statistical analyses|designed the study and drafted the manuscript	performed most of the statistical analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4441647	26020016	SA	2	generated the strains used|performed most of the mass measurement|performed most of the statistical analyses|designed the study and drafted the manuscript	designed the study and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
1866182	17520014	DD	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1866182	17520014	DD	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1866182	17520014	DD	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1866182	17520014	HL	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1866182	17520014	HL	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1866182	17520014	IA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1866182	17520014	IA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1866182	17520014	IA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1866182	17520014	YW	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1866182	17520014	YW	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5515722	28721684	AJ	2	drafted and edited the manuscript|performed the dosimetry calculations	drafted and edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5515722	28721684	AJ	2	drafted and edited the manuscript|performed the dosimetry calculations	performed the dosimetry calculations	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5515722	28721684	GS	2	drafted and edited the manuscript|performed the dosimetry calculations	drafted and edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5515722	28721684	GS	2	drafted and edited the manuscript|performed the dosimetry calculations	performed the dosimetry calculations	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5515722	28721684	JRN	2	drafted and edited the manuscript|were responsible for maintaining cell lines and animals used	drafted and edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5515722	28721684	JRN	2	drafted and edited the manuscript|were responsible for maintaining cell lines and animals used	were responsible for maintaining cell lines and animals used	Performed the experiments	Investigation	YES
5515722	28721684	RH	2	performed the dosimetry calculations	performed the dosimetry calculations	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5515722	28721684	SP	2	were responsible for maintaining cell lines and animals used	were responsible for maintaining cell lines and animals used	Performed the experiments	Investigation	YES
5701633	29209336	CZ	PLoS52	contributed equally to this work|constructed the database	contributed equally to this work	-	-	NO
5701633	29209336	CZ	PLoS52	contributed equally to this work|constructed the database	constructed the database	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5701633	29209336	HA	PLoS52	led the research	led the research	-	-	NO
5701633	29209336	QL	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5701633	29209336	SH	PLoS52	led the research	led the research	-	-	NO
5701633	29209336	TW	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5701633	29209336	W-HC	PLoS52	led the research|wrote and revised the manuscript	led the research	-	-	NO
5701633	29209336	W-HC	PLoS52	led the research|wrote and revised the manuscript	wrote and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5701633	29209336	WL	PLoS52	contributed equally to this work|analyzed the data|wrote and revised the manuscript	contributed equally to this work	-	-	NO
5701633	29209336	WL	PLoS52	contributed equally to this work|analyzed the data|wrote and revised the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5701633	29209336	WL	PLoS52	contributed equally to this work|analyzed the data|wrote and revised the manuscript	wrote and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5701633	29209336	ZH	PLoS52	contributed equally to this work|constructed the database|wrote and revised the manuscript	contributed equally to this work	-	-	NO
5701633	29209336	ZH	PLoS52	contributed equally to this work|constructed the database|wrote and revised the manuscript	constructed the database	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5701633	29209336	ZH	PLoS52	contributed equally to this work|constructed the database|wrote and revised the manuscript	wrote and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6352567	30713671	HL	1	Manuscript writing	Manuscript writing	Wrote the paper	Writing - Original Draft	YES
5559785	28814272	AO	2	analyzed ms-data	analyzed ms-data	Analyzed the data	Formal analysis	YES
5559785	28814272	BG	2	analyzed ms-data	analyzed ms-data	Analyzed the data	Formal analysis	YES
5559785	28814272	DB	2	analyzed ms-data	analyzed ms-data	Analyzed the data	Formal analysis	YES
5559785	28814272	NA	2	characterized the t6ss|reviewed the manuscript	characterized the t6ss	Performed the experiments	Investigation	YES
5559785	28814272	NA	2	characterized the t6ss|reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5559785	28814272	UA	2	planned experimental approach|interpreted ms-data and validated new and re-annotated proteins	planned experimental approach	Conceived and designed the experiments	Conceptualization	YES
5559785	28814272	UA	2	planned experimental approach|interpreted ms-data and validated new and re-annotated proteins	interpreted ms-data and validated new and re-annotated proteins	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Validation	YES
5559785	28814272	UB	2	planned experimental approach|reviewed the manuscript	planned experimental approach	Conceived and designed the experiments	Conceptualization	YES
5559785	28814272	UB	2	planned experimental approach|reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5559785	28814272	all authors	2	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
4456594	26054735	AR	2	carried out fermentation experiments and helped to draft the manuscript	carried out fermentation experiments and helped to draft the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4456594	26054735	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4456594	26054735	BG	2	participated in the design of the study and helped to draft the manuscript	participated in the design of the study and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4456594	26054735	CF-S	2	carried out molecular genetic studies and fermentation experiments and helped to draft the manuscript	carried out molecular genetic studies and fermentation experiments and helped to draft the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4456594	26054735	DR	2	conceived the study and helped to draft the manuscript	conceived the study and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4456594	26054735	JLG	2	designed and coordinated the study and drafted the manuscript	designed and coordinated the study and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft	YES
4456594	26054735	MT	2	participated in the design of the study and helped to draft the manuscript	participated in the design of the study and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4456594	26054735	V. Morales	2	for technical support	for technical support	Performed the experiments	Investigation	YES
1866221	17505546	AJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1866221	17505546	AJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1866221	17505546	AJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1866221	17505546	AJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1866221	17505546	AJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1866221	17505546	AS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1866221	17505546	EA	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1866221	17505546	GP	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1866221	17505546	GP	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1866221	17505546	GS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1866221	17505546	GS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1866221	17505546	GS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1866221	17505546	MC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1866221	17505546	MC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1866221	17505546	MC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1866221	17505546	SA	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1866221	17505546	SA	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4412671	25919586	HM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4412671	25919586	KK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412671	25919586	KK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4412671	25919586	KK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412671	25919586	KN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412671	25919586	KN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4412671	25919586	KN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412671	25919586	KY	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4412671	25919586	SP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412671	25919586	SP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412671	25919586	SP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412671	25919586	SP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412671	25919586	SP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412671	25919586	TY	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412671	25919586	TY	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4412671	25919586	YK	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2806942	20119484	All authors	2	contributed to critique and modification of the manuscript and read and approved the final version	contributed to critique and modification of the manuscript and read and approved the final version	Wrote the paper	Writing - Review & Editing	YES
2806942	20119484	DO	2	contributed to the study design, data management, analysis and interpretation, and co-wrote the first draft of the article|is guarantor of the paper	contributed to the study design, data management, analysis and interpretation, and co-wrote the first draft of the article	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Data curation|Formal analysis|Methodology|Resources|Writing - Original Draft	YES
2806942	20119484	DO	2	contributed to the study design, data management, analysis and interpretation, and co-wrote the first draft of the article|is guarantor of the paper	is guarantor of the paper	-	-	NO
2806942	20119484	GA	2	worked on the analysis and interpretation of the data and co-wrote the first draft of the article	worked on the analysis and interpretation of the data and co-wrote the first draft of the article	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
2806942	20119484	NSM	2	was the project coordinator, contributed to the design of the study and participated in data analysis and interpretation	was the project coordinator, contributed to the design of the study and participated in data analysis and interpretation	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Methodology|Project administration|Resources	YES
2806942	20119484	SD	2	contributed to the study design, were responsible for the management of data collection and entry, and participated in data analysis and interpretation	contributed to the study design, were responsible for the management of data collection and entry, and participated in data analysis and interpretation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Formal analysis|Investigation|Methodology|Resources	YES
2806942	20119484	UB	2	contributed to the study design, were responsible for the management of data collection and entry, and participated in data analysis and interpretation	contributed to the study design, were responsible for the management of data collection and entry, and participated in data analysis and interpretation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Formal analysis|Investigation|Methodology|Resources	YES
5701636	29209338	DV	2	conceived the idea, performed all the analyses, and wrote the manuscript	conceived the idea, performed all the analyses, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
5520824	28733954	AF	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5520824	28733954	AV	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5520824	28733954	All authors	2	critically revised the article and approved of the final version for publication	critically revised the article and approved of the final version for publication	Wrote the paper	Writing - Review & Editing	YES
5520824	28733954	GJM	2	conceived of the study|designed the study|analysed the data and interpreted the results|drafted the article	conceived of the study	Conceived and designed the experiments	Conceptualization	YES
5520824	28733954	GJM	2	conceived of the study|designed the study|analysed the data and interpreted the results|drafted the article	designed the study	Conceived and designed the experiments	Methodology	YES
5520824	28733954	GJM	2	conceived of the study|designed the study|analysed the data and interpreted the results|drafted the article	analysed the data and interpreted the results	Analyzed the data	Formal analysis	YES
5520824	28733954	GJM	2	conceived of the study|designed the study|analysed the data and interpreted the results|drafted the article	drafted the article	Wrote the paper	Writing - Original Draft	YES
5520824	28733954	LF	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5520824	28733954	PPS	2	conceived of the study|designed the study|analysed the data and interpreted the results|drafted the article	conceived of the study	Conceived and designed the experiments	Conceptualization	YES
5520824	28733954	PPS	2	conceived of the study|designed the study|analysed the data and interpreted the results|drafted the article	designed the study	Conceived and designed the experiments	Methodology	YES
5520824	28733954	PPS	2	conceived of the study|designed the study|analysed the data and interpreted the results|drafted the article	analysed the data and interpreted the results	Analyzed the data	Formal analysis	YES
5520824	28733954	PPS	2	conceived of the study|designed the study|analysed the data and interpreted the results|drafted the article	drafted the article	Wrote the paper	Writing - Original Draft	YES
5520824	28733954	SC	2	conceived of the study|designed the study|drafted the article	conceived of the study	Conceived and designed the experiments	Conceptualization	YES
5520824	28733954	SC	2	conceived of the study|designed the study|drafted the article	designed the study	Conceived and designed the experiments	Methodology	YES
5520824	28733954	SC	2	conceived of the study|designed the study|drafted the article	drafted the article	Wrote the paper	Writing - Original Draft	YES
6352568	30713672	XT	1	Writing the manuscript	Writing the manuscript	Wrote the paper	Writing - Original Draft	YES
3117468	21546375	J.E.	2	both have equally contributed to the manuscript	both have equally contributed to the manuscript	-	-	NO
3117468	21546375	S.E.	2	both have equally contributed to the manuscript	both have equally contributed to the manuscript	-	-	NO
1866243	17520019	EH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1866243	17520019	EH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1866243	17520019	EH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1866243	17520019	EH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1866243	17520019	ID	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1866243	17520019	PB	PLoS5	Conceived and designed the experiments|Edited paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1866243	17520019	PB	PLoS5	Conceived and designed the experiments|Edited paper	Edited paper	Wrote the paper	Writing - Review & Editing	YES
1866243	17520019	VS	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4600481	26491659	Changchen Hu	2	contributed equally to this work and should be considered co-first authors	contributed equally to this work and should be considered co-first authors	-	-	NO
4600481	26491659	Hongming Ji	2	contributed equally to this work and should be considered co-first authors	contributed equally to this work and should be considered co-first authors	-	-	NO
4456602	26054734	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4456602	26054734	HA	2	revised the manuscript for important intellectual content	revised the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4456602	26054734	MM	2	revised the manuscript for important intellectual content	revised the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4456602	26054734	TH	2	conceived and designed this study, performed the experiment, and drafted the manuscript	conceived and designed this study, performed the experiment, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Writing - Original Draft	YES
4412673	25919394	KM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412673	25919394	KM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412673	25919394	KM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412673	25919394	KM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412673	25919394	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412673	25919394	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412673	25919394	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412673	25919394	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412673	25919394	MJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412673	25919394	MJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412673	25919394	MJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412673	25919394	TO	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412673	25919394	TO	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412673	25919394	TO	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5559791	28814270	All coauthors	2	reviewed, revised, commented on, and approved the final version of the manuscript	reviewed, revised, commented on, and approved the final version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5559791	28814270	CWR	2	performed the qrt-pcr analyses and wrote the first draft of the manuscript	performed the qrt-pcr analyses and wrote the first draft of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5559791	28814270	ELBD	2	designed and carried out the animal experiment	designed and carried out the animal experiment	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5559791	28814270	JS	2	secured funding|designed and carried out the animal experiment	secured funding	-	Funding acquisition	YES
5559791	28814270	JS	2	secured funding|designed and carried out the animal experiment	designed and carried out the animal experiment	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5559791	28814270	LAC	2	secured funding|designed and carried out the animal experiment	secured funding	-	Funding acquisition	YES
5559791	28814270	LAC	2	secured funding|designed and carried out the animal experiment	designed and carried out the animal experiment	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5559791	28814270	MJD	2	designed and carried out the animal experiment	designed and carried out the animal experiment	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5559791	28814270	SEA	2	secured funding|designed and carried out the animal experiment	secured funding	-	Funding acquisition	YES
5559791	28814270	SEA	2	secured funding|designed and carried out the animal experiment	designed and carried out the animal experiment	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5559791	28814270	TEP	2	secured funding|designed and carried out the animal experiment	secured funding	-	Funding acquisition	YES
5559791	28814270	TEP	2	secured funding|designed and carried out the animal experiment	designed and carried out the animal experiment	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5559791	28814270	WC	2	isolated rna from the abdominal fat samples, labeled, hybridized and scanned the microarrays	isolated rna from the abdominal fat samples, labeled, hybridized and scanned the microarrays	Performed the experiments	Investigation	YES
2892744	20640034	AM	2	participated in data interpretation|participated in the preparation of the report and approved the final version	participated in data interpretation	Analyzed the data	Formal analysis	YES
2892744	20640034	AM	2	participated in data interpretation|participated in the preparation of the report and approved the final version	participated in the preparation of the report and approved the final version	-	-	NO
2892744	20640034	DR	2	participated in data collection|participated in the preparation of the report and approved the final version	participated in data collection	Performed the experiments	Investigation	YES
2892744	20640034	DR	2	participated in data collection|participated in the preparation of the report and approved the final version	participated in the preparation of the report and approved the final version	-	-	NO
2892744	20640034	FK	2	participated in data collection|supervised the follow-up of patients|participated in the preparation of the report and approved the final version	participated in data collection	Performed the experiments	Investigation	YES
2892744	20640034	FK	2	participated in data collection|supervised the follow-up of patients|participated in the preparation of the report and approved the final version	supervised the follow-up of patients	-	Supervision	YES
2892744	20640034	FK	2	participated in data collection|supervised the follow-up of patients|participated in the preparation of the report and approved the final version	participated in the preparation of the report and approved the final version	-	-	NO
2892744	20640034	JCSF	2	contributed to the design of the studies|participated in data collection|participated in data entry|participated in data interpretation|conducted analysis of data|participated in the preparation of the report and approved the final version|are joint guarantors of the paper	contributed to the design of the studies	Conceived and designed the experiments	Methodology	YES
2892744	20640034	JCSF	2	contributed to the design of the studies|participated in data collection|participated in data entry|participated in data interpretation|conducted analysis of data|participated in the preparation of the report and approved the final version|are joint guarantors of the paper	participated in data collection	Performed the experiments	Investigation	YES
2892744	20640034	JCSF	2	contributed to the design of the studies|participated in data collection|participated in data entry|participated in data interpretation|conducted analysis of data|participated in the preparation of the report and approved the final version|are joint guarantors of the paper	participated in data entry	Analyzed the data	Data curation	YES
2892744	20640034	JCSF	2	contributed to the design of the studies|participated in data collection|participated in data entry|participated in data interpretation|conducted analysis of data|participated in the preparation of the report and approved the final version|are joint guarantors of the paper	participated in data interpretation	Analyzed the data	Formal analysis	YES
2892744	20640034	JCSF	2	contributed to the design of the studies|participated in data collection|participated in data entry|participated in data interpretation|conducted analysis of data|participated in the preparation of the report and approved the final version|are joint guarantors of the paper	conducted analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
2892744	20640034	JCSF	2	contributed to the design of the studies|participated in data collection|participated in data entry|participated in data interpretation|conducted analysis of data|participated in the preparation of the report and approved the final version|are joint guarantors of the paper	participated in the preparation of the report and approved the final version	-	-	NO
2892744	20640034	JCSF	2	contributed to the design of the studies|participated in data collection|participated in data entry|participated in data interpretation|conducted analysis of data|participated in the preparation of the report and approved the final version|are joint guarantors of the paper	are joint guarantors of the paper	-	-	NO
2892744	20640034	JP	2	participated in data collection|participated in data entry|participated in the preparation of the report and approved the final version	participated in data collection	Performed the experiments	Investigation	YES
2892744	20640034	JP	2	participated in data collection|participated in data entry|participated in the preparation of the report and approved the final version	participated in data entry	Analyzed the data	Data curation	YES
2892744	20640034	JP	2	participated in data collection|participated in data entry|participated in the preparation of the report and approved the final version	participated in the preparation of the report and approved the final version	-	-	NO
2892744	20640034	JRS	2	contributed to the design of the studies|participated in data collection|participated in data interpretation|participated in the preparation of the report and approved the final version|are joint guarantors of the paper	contributed to the design of the studies	Conceived and designed the experiments	Methodology	YES
2892744	20640034	JRS	2	contributed to the design of the studies|participated in data collection|participated in data interpretation|participated in the preparation of the report and approved the final version|are joint guarantors of the paper	participated in data collection	Performed the experiments	Investigation	YES
2892744	20640034	JRS	2	contributed to the design of the studies|participated in data collection|participated in data interpretation|participated in the preparation of the report and approved the final version|are joint guarantors of the paper	participated in data interpretation	Analyzed the data	Formal analysis	YES
2892744	20640034	JRS	2	contributed to the design of the studies|participated in data collection|participated in data interpretation|participated in the preparation of the report and approved the final version|are joint guarantors of the paper	participated in the preparation of the report and approved the final version	-	-	NO
2892744	20640034	JRS	2	contributed to the design of the studies|participated in data collection|participated in data interpretation|participated in the preparation of the report and approved the final version|are joint guarantors of the paper	are joint guarantors of the paper	-	-	NO
2892744	20640034	MB	2	participated in data collection|participated in data entry|participated in data interpretation|participated in the preparation of the report and approved the final version	participated in data collection	Performed the experiments	Investigation	YES
2892744	20640034	MB	2	participated in data collection|participated in data entry|participated in data interpretation|participated in the preparation of the report and approved the final version	participated in data entry	Analyzed the data	Data curation	YES
2892744	20640034	MB	2	participated in data collection|participated in data entry|participated in data interpretation|participated in the preparation of the report and approved the final version	participated in data interpretation	Analyzed the data	Formal analysis	YES
2892744	20640034	MB	2	participated in data collection|participated in data entry|participated in data interpretation|participated in the preparation of the report and approved the final version	participated in the preparation of the report and approved the final version	-	-	NO
2892744	20640034	MD	2	participated in data collection|participated in data entry|supervised the follow-up of patients|participated in the preparation of the report and approved the final version	participated in data collection	Performed the experiments	Investigation	YES
2892744	20640034	MD	2	participated in data collection|participated in data entry|supervised the follow-up of patients|participated in the preparation of the report and approved the final version	participated in data entry	Analyzed the data	Data curation	YES
2892744	20640034	MD	2	participated in data collection|participated in data entry|supervised the follow-up of patients|participated in the preparation of the report and approved the final version	supervised the follow-up of patients	-	Supervision	YES
2892744	20640034	MD	2	participated in data collection|participated in data entry|supervised the follow-up of patients|participated in the preparation of the report and approved the final version	participated in the preparation of the report and approved the final version	-	-	NO
2892744	20640034	NBK	2	contributed to the design of the studies|participated in data interpretation|participated in the preparation of the report and approved the final version	contributed to the design of the studies	Conceived and designed the experiments	Methodology	YES
2892744	20640034	NBK	2	contributed to the design of the studies|participated in data interpretation|participated in the preparation of the report and approved the final version	participated in data interpretation	Analyzed the data	Formal analysis	YES
2892744	20640034	NBK	2	contributed to the design of the studies|participated in data interpretation|participated in the preparation of the report and approved the final version	participated in the preparation of the report and approved the final version	-	-	NO
3248356	22152427	AG	2	developed the study protocol|were in charge of the recruitment of the subjects|participated in data collection	developed the study protocol	Conceived and designed the experiments	Methodology	YES
3248356	22152427	AG	2	developed the study protocol|were in charge of the recruitment of the subjects|participated in data collection	were in charge of the recruitment of the subjects	Performed the experiments	Investigation	YES
3248356	22152427	AG	2	developed the study protocol|were in charge of the recruitment of the subjects|participated in data collection	participated in data collection	Performed the experiments	Investigation	YES
3248356	22152427	GYM	2	developed the study protocol|participated in data collection|was responsible for the central and peripheral fatigue measurements	developed the study protocol	Conceived and designed the experiments	Methodology	YES
3248356	22152427	GYM	2	developed the study protocol|participated in data collection|was responsible for the central and peripheral fatigue measurements	participated in data collection	Performed the experiments	Investigation	YES
3248356	22152427	GYM	2	developed the study protocol|participated in data collection|was responsible for the central and peripheral fatigue measurements	was responsible for the central and peripheral fatigue measurements	Performed the experiments	Investigation	YES
3248356	22152427	JBM	2	participated in data collection	participated in data collection	Performed the experiments	Investigation	YES
3248356	22152427	JFL	2	developed the study protocol	developed the study protocol	Conceived and designed the experiments	Methodology	YES
3248356	22152427	LF	2	were in charge of the recruitment of the subjects|participated in data collection	were in charge of the recruitment of the subjects	Performed the experiments	Investigation	YES
3248356	22152427	LF	2	were in charge of the recruitment of the subjects|participated in data collection	participated in data collection	Performed the experiments	Investigation	YES
3248356	22152427	LM	2	developed the study protocol|was the project leader of this study|were in charge of the recruitment of the subjects	developed the study protocol	Conceived and designed the experiments	Methodology	YES
3248356	22152427	LM	2	developed the study protocol|was the project leader of this study|were in charge of the recruitment of the subjects	was the project leader of this study	-	Supervision	YES
3248356	22152427	LM	2	developed the study protocol|was the project leader of this study|were in charge of the recruitment of the subjects	were in charge of the recruitment of the subjects	Performed the experiments	Investigation	YES
3248356	22152427	LV	2	were in charge of the recruitment of the subjects|was in charge of data collection and management	were in charge of the recruitment of the subjects	Performed the experiments	Investigation	YES
3248356	22152427	LV	2	were in charge of the recruitment of the subjects|was in charge of data collection and management	was in charge of data collection and management	Performed the experiments	Investigation	YES
3248356	22152427	MG	2	developed the study protocol|participated in data collection	developed the study protocol	Conceived and designed the experiments	Methodology	YES
3248356	22152427	MG	2	developed the study protocol|participated in data collection	participated in data collection	Performed the experiments	Investigation	YES
3248356	22152427	PS	2	developed the study protocol	developed the study protocol	Conceived and designed the experiments	Methodology	YES
3248356	22152427	SLP	2	developed the study protocol|was responsible for the statistical analysis	developed the study protocol	Conceived and designed the experiments	Methodology	YES
3248356	22152427	SLP	2	developed the study protocol|was responsible for the statistical analysis	was responsible for the statistical analysis	Analyzed the data	Formal analysis	YES
5524658	28741281	ATH	2	performed data analysis|drafted the initial manuscript version	performed data analysis	Analyzed the data	Formal analysis	YES
5524658	28741281	ATH	2	performed data analysis|drafted the initial manuscript version	drafted the initial manuscript version	Wrote the paper	Writing - Original Draft	YES
5524658	28741281	All authors	2	contributed to interpretation of data, manuscript revisions, and approval of the final draft	contributed to interpretation of data, manuscript revisions, and approval of the final draft	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5524658	28741281	BLW	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5524658	28741281	DH	2	oversaw animal care and imaging data acquisition|performed data analysis	oversaw animal care and imaging data acquisition	Performed the experiments|Analyzed the data	Investigation|Supervision|Visualization	YES
5524658	28741281	DH	2	oversaw animal care and imaging data acquisition|performed data analysis	performed data analysis	Analyzed the data	Formal analysis	YES
5524658	28741281	KF	2	oversaw animal care and imaging data acquisition|performed data analysis	oversaw animal care and imaging data acquisition	Performed the experiments|Analyzed the data	Investigation|Supervision|Visualization	YES
5524658	28741281	KF	2	oversaw animal care and imaging data acquisition|performed data analysis	performed data analysis	Analyzed the data	Formal analysis	YES
5524658	28741281	KPC	2	designed the study|drafted the initial manuscript version	designed the study	Conceived and designed the experiments	Methodology	YES
5524658	28741281	KPC	2	designed the study|drafted the initial manuscript version	drafted the initial manuscript version	Wrote the paper	Writing - Original Draft	YES
5524658	28741281	NN	2	oversaw radiolabeling|performed data analysis	oversaw radiolabeling	Performed the experiments	Investigation|Supervision	YES
5524658	28741281	NN	2	oversaw radiolabeling|performed data analysis	performed data analysis	Analyzed the data	Formal analysis	YES
5524658	28741281	REC	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5701648	29209339	BRs	2	enzyme activities and gene expressions	enzyme activities and gene expressions	Performed the experiments	Investigation	YES
5701648	29209339	DL	2	cloned socyp85a1 gene	cloned socyp85a1 gene	Performed the experiments	Investigation	YES
5701648	29209339	FD	2	designed and performed part of the experiments|cloned socyp85a1 gene	designed and performed part of the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5701648	29209339	FD	2	designed and performed part of the experiments|cloned socyp85a1 gene	cloned socyp85a1 gene	Performed the experiments	Investigation	YES
5701648	29209339	WS	2	designed and performed part of the experiments|analyzed the data and wrote the manuscript	designed and performed part of the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5701648	29209339	WS	2	designed and performed part of the experiments|analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4412674	25919587	AMN	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412674	25919587	AMN	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412674	25919587	AMN	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412674	25919587	AW	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412674	25919587	AW	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412674	25919587	AW	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412674	25919587	JC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412674	25919587	JC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412674	25919587	JC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412674	25919587	JC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412674	25919587	JJT	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412674	25919587	JJT	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412674	25919587	JJT	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412674	25919587	JWH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412674	25919587	JWH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412674	25919587	JWH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4460183	26054733	AR	2	carried out the molecular genetic studies and recombinant protein production|drafted the manuscript which was critically revisited by all authors	carried out the molecular genetic studies and recombinant protein production	Performed the experiments	Investigation	YES
4460183	26054733	AR	2	carried out the molecular genetic studies and recombinant protein production|drafted the manuscript which was critically revisited by all authors	drafted the manuscript which was critically revisited by all authors	Wrote the paper	Writing - Original Draft	YES
4460183	26054733	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4460183	26054733	CC	2	carried out the molecular genetic studies and recombinant protein production	carried out the molecular genetic studies and recombinant protein production	Performed the experiments	Investigation	YES
4460183	26054733	DT	2	drafted the manuscript which was critically revisited by all authors	drafted the manuscript which was critically revisited by all authors	Wrote the paper	Writing - Original Draft	YES
4460183	26054733	TH	2	carried out the molecular genetic studies and recombinant protein production	carried out the molecular genetic studies and recombinant protein production	Performed the experiments	Investigation	YES
4460183	26054733	WJHB	2	drafted the manuscript which was critically revisited by all authors	drafted the manuscript which was critically revisited by all authors	Wrote the paper	Writing - Original Draft	YES
6352569	30713665	DPW	CRediT	project administration	project administration	-	Project administration	YES
6352569	30713665	HHZ	CRediT	investigation	investigation	Performed the experiments	Investigation	YES
6352569	30713665	JBS	CRediT	investigation	investigation	Performed the experiments	Investigation	YES
6352569	30713665	LZ	CRediT	Concept of design	Concept of design	Conceived and designed the experiments	Conceptualization	YES
6352569	30713665	MQZ	CRediT	project administration	project administration	-	Project administration	YES
6352569	30713665	TLQ	CRediT	investigation	investigation	Performed the experiments	Investigation	YES
6352569	30713665	YML	CRediT	investigation	investigation	Performed the experiments	Investigation	YES
3261811	22168756	AHL	2	participated in manuscript design, interpretation and preparation of the manuscript	participated in manuscript design, interpretation and preparation of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3261811	22168756	CRL	2	participated in manuscript design, wrote the first draft of the manuscript	participated in manuscript design, wrote the first draft of the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
3261811	22168756	DFSC	2	participated in the interpretation and preparation of the manuscript	participated in the interpretation and preparation of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3261811	22168756	HN	2	participated in the interpretation and preparation of the manuscript	participated in the interpretation and preparation of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3261811	22168756	NEZ	2	participated in the interpretation and preparation of the manuscript	participated in the interpretation and preparation of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3004029	21270957	All authors	2	were involved in conceptualising, drafting and revising the review	were involved in conceptualising, drafting and revising the review	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
3004029	21270957	BSC	2	carried out the literature review	carried out the literature review	Performed the experiments	Formal analysis|Investigation	YES
3004029	21270957	LJW	2	is guarantor of the paper	is guarantor of the paper	-	-	NO
3004029	21270957	RJM	2	carried out the literature review	carried out the literature review	Performed the experiments	Formal analysis|Investigation	YES
3004029	21270957	YL	2	carried out the literature review	carried out the literature review	Performed the experiments	Formal analysis|Investigation	YES
5559799	28814265	CB	2	supervised and assisted in the ngs data analysis and prepared the final manuscript	supervised and assisted in the ngs data analysis and prepared the final manuscript	Analyzed the data|Wrote the paper	Formal analysis|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
5559799	28814265	EE	2	supervised and assisted in the ngs data analysis and prepared the final manuscript	supervised and assisted in the ngs data analysis and prepared the final manuscript	Analyzed the data|Wrote the paper	Formal analysis|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
5559799	28814265	GDM	2	supervised and assisted in the ngs data analysis and prepared the final manuscript	supervised and assisted in the ngs data analysis and prepared the final manuscript	Analyzed the data|Wrote the paper	Formal analysis|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
5559799	28814265	ME	2	supervised and assisted in the ngs data analysis and prepared the final manuscript	supervised and assisted in the ngs data analysis and prepared the final manuscript	Analyzed the data|Wrote the paper	Formal analysis|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
5559799	28814265	MMZ	2	designed the research|carried out the experiment, analyzed the data and drafted the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
5559799	28814265	MMZ	2	designed the research|carried out the experiment, analyzed the data and drafted the manuscript	carried out the experiment, analyzed the data and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5559799	28814265	SMS	2	designed the research|supervised and assisted in the ngs data analysis and prepared the final manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
5559799	28814265	SMS	2	designed the research|supervised and assisted in the ngs data analysis and prepared the final manuscript	supervised and assisted in the ngs data analysis and prepared the final manuscript	Analyzed the data|Wrote the paper	Formal analysis|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
5529305	28748524	B. All	2	authors participated in drafting and revising this paper	authors participated in drafting and revising this paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
1866245	17520022	DB	1	Participated in the design and coordination of the study and helped to draft and finalize the manuscript	Participated in the design and coordination of the study and helped to draft and finalize the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft|Writing - Review & Editing	YES
1866245	17520022	DK	1	Participated in the computational analysis and in the preparation of the manuscript	Participated in the computational analysis and in the preparation of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
1866245	17520022	KB	1	Participated in the computation analysis	Participated in the computation analysis	Analyzed the data	Formal analysis	YES
3267647	22206347	All authors	2	have effectively contributed to this work in its different production stages	have effectively contributed to this work in its different production stages	-	-	NO
4412676	25919688	CWC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412676	25919688	CWC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412676	25919688	CWC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412676	25919688	CWC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412676	25919688	CWC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412676	25919688	CWH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4412676	25919688	CYL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4412676	25919688	ICW	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4412676	25919688	JYW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412676	25919688	JYW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412676	25919688	JYW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412676	25919688	WCC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4412676	25919688	WCC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412676	25919688	WHH	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4412676	25919688	YCF	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4412676	25919688	YCF	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412676	25919688	YTL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412676	25919688	YTL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412676	25919688	YTL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412676	25919688	YTL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412676	25919688	YTL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6352570	30713666	MH	1	Performing clinical studies	Performing clinical studies	Performed the experiments	Investigation	YES
6352570	30713666	TM	1	Performing clinical studies	Performing clinical studies	Performed the experiments	Investigation	YES
3081098	21637318	DSG	2	all undertook all the duties of authorship|provided technical input	all undertook all the duties of authorship	Performed the experiments	Investigation	YES
3081098	21637318	DSG	2	all undertook all the duties of authorship|provided technical input	provided technical input	-	-	NO
3081098	21637318	RD	2	all undertook all the duties of authorship	all undertook all the duties of authorship	Performed the experiments	Investigation	YES
3081098	21637318	VP	2	all undertook all the duties of authorship|is guarantor of the paper	all undertook all the duties of authorship	Performed the experiments	Investigation	YES
3081098	21637318	VP	2	all undertook all the duties of authorship|is guarantor of the paper	is guarantor of the paper	-	-	NO
4460186	26054736	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4460186	26054736	Garabed Antranikian	2	for his generous support and the access to laboratory facilities	for his generous support and the access to laboratory facilities	-	-	NO
4460186	26054736	MN	2	performed research	performed research	Performed the experiments	Investigation	YES
4460186	26054736	SE	2	conceived and supervised the study and wrote the manuscript	conceived and supervised the study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Supervision|Writing - Original Draft	YES
5701814	29209350	HW	2	supervised the study and complemented the writing	supervised the study and complemented the writing	Wrote the paper	Supervision	YES
5701814	29209350	KE	2	analyzed data and complemented the writing	analyzed data and complemented the writing	Analyzed the data|Wrote the paper	Formal analysis	YES
5701814	29209350	KK	2	conceived the study, analyzed data, and wrote the manuscript	conceived the study, analyzed data, and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
5548701	28791653	PKG	4	The manuscript was written by|all the experiments were designed by	The manuscript was written by	Wrote the paper	Writing - Original Draft	YES
5548701	28791653	PKG	4	The manuscript was written by|all the experiments were designed by	all the experiments were designed by	Conceived and designed the experiments	Methodology	YES
5548701	28791653	RN	4	The Chemistry and radiochemistry was designed and performed by	The Chemistry and radiochemistry was designed and performed by	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5548701	28791653	SG	4	The Chemistry and radiochemistry was designed and performed by|all the experiments were designed by	The Chemistry and radiochemistry was designed and performed by	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5548701	28791653	SG	4	The Chemistry and radiochemistry was designed and performed by|all the experiments were designed by	all the experiments were designed by	Conceived and designed the experiments	Methodology	YES
5548701	28791653	VG	4	The in vitro assays and cell binding assays were conducted by	The in vitro assays and cell binding assays were conducted by	Performed the experiments	Investigation	YES
5548701	28791653	YW	4	The microPET data was analyzed by	The microPET data was analyzed by	Analyzed the data	Formal analysis	YES
3283512	22176668	DM	2	was involved in data collection and editing the manuscript	was involved in data collection and editing the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
3283512	22176668	LYB	2	was the primary author of the manuscript	was the primary author of the manuscript	Wrote the paper	Writing - Original Draft	YES
3283512	22176668	TP	2	was involved in subject recruitment, data collection and helped to draft the manuscript	was involved in subject recruitment, data collection and helped to draft the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3283512	22176668	YPP	2	conceived of the study, participated in its design and coordination and helped to draft the manuscript	conceived of the study, participated in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
5559819	28814267	GR	2	conceived the study, participated in its design, coordination and drafted the manuscript|carried out rna extraction, cdna synthesis and additional bioinformatics downstream analysis	conceived the study, participated in its design, coordination and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
5559819	28814267	GR	2	conceived the study, participated in its design, coordination and drafted the manuscript|carried out rna extraction, cdna synthesis and additional bioinformatics downstream analysis	carried out rna extraction, cdna synthesis and additional bioinformatics downstream analysis	Performed the experiments	Formal analysis|Investigation	YES
5559819	28814267	JA	2	participated in the design, coordination and assisted with the manuscript draft and provided funding	participated in the design, coordination and assisted with the manuscript draft and provided funding	Conceived and designed the experiments|Wrote the paper	Funding acquisition|Project administration|Writing - Original Draft	YES
5559819	28814267	JBC	2	participated in the design, coordination and assisted with the manuscript draft and provided funding	participated in the design, coordination and assisted with the manuscript draft and provided funding	Conceived and designed the experiments|Wrote the paper	Funding acquisition|Project administration|Writing - Original Draft	YES
5559819	28814267	KD	2	was involved in the sequencing and validation of genes and helped draft the manuscript	was involved in the sequencing and validation of genes and helped draft the manuscript	Performed the experiments|Wrote the paper	Investigation|Validation|Writing - Original Draft	YES
5559819	28814267	LR	2	performed part of the bioinformatics analysis	performed part of the bioinformatics analysis	Performed the experiments	Formal analysis|Investigation	YES
5559819	28814267	PM	2	conceived the study, participated in its design, coordination and drafted the manuscript	conceived the study, participated in its design, coordination and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
5559819	28814267	TV	2	carried out the analysis of data and critically revised the manuscript	carried out the analysis of data and critically revised the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
5559819	28814267	TVN	2	conceived the study, participated in its design, coordination and drafted the manuscript|carried out rna extraction, cdna synthesis and additional bioinformatics downstream analysis	conceived the study, participated in its design, coordination and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
5559819	28814267	TVN	2	conceived the study, participated in its design, coordination and drafted the manuscript|carried out rna extraction, cdna synthesis and additional bioinformatics downstream analysis	carried out rna extraction, cdna synthesis and additional bioinformatics downstream analysis	Performed the experiments	Formal analysis|Investigation	YES
5559819	28814267	VC	2	was involved in sanger sequencing confirmation and laboratory assistance	was involved in sanger sequencing confirmation and laboratory assistance	Performed the experiments	Investigation	YES
5559819	28814267	VS	2	contributed to the sampling, dissection and provided an extra dataset for the current study	contributed to the sampling, dissection and provided an extra dataset for the current study	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4959927	27194814	Both authors	2	contributed equally to this article	contributed equally to this article	-	-	NO
3407873	22876272	JCSF	PLoS52	conceived and designed the study|analysed the data|interpreted the data|drafted the manuscript|revised the manuscript for intellectual content, and read and approved the final version	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3407873	22876272	JCSF	PLoS52	conceived and designed the study|analysed the data|interpreted the data|drafted the manuscript|revised the manuscript for intellectual content, and read and approved the final version	analysed the data	Analyzed the data	Formal analysis	YES
3407873	22876272	JCSF	PLoS52	conceived and designed the study|analysed the data|interpreted the data|drafted the manuscript|revised the manuscript for intellectual content, and read and approved the final version	interpreted the data	Analyzed the data	Formal analysis	YES
3407873	22876272	JCSF	PLoS52	conceived and designed the study|analysed the data|interpreted the data|drafted the manuscript|revised the manuscript for intellectual content, and read and approved the final version	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
3407873	22876272	JCSF	PLoS52	conceived and designed the study|analysed the data|interpreted the data|drafted the manuscript|revised the manuscript for intellectual content, and read and approved the final version	revised the manuscript for intellectual content, and read and approved the final version	Wrote the paper	Writing - Review & Editing	YES
3407873	22876272	JRS	PLoS52	conceived and designed the study|interpreted the data|drafted the manuscript|revised the manuscript for intellectual content, and read and approved the final version|is guarantor of the paper	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3407873	22876272	JRS	PLoS52	conceived and designed the study|interpreted the data|drafted the manuscript|revised the manuscript for intellectual content, and read and approved the final version|is guarantor of the paper	interpreted the data	Analyzed the data	Formal analysis	YES
3407873	22876272	JRS	PLoS52	conceived and designed the study|interpreted the data|drafted the manuscript|revised the manuscript for intellectual content, and read and approved the final version|is guarantor of the paper	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
3407873	22876272	JRS	PLoS52	conceived and designed the study|interpreted the data|drafted the manuscript|revised the manuscript for intellectual content, and read and approved the final version|is guarantor of the paper	revised the manuscript for intellectual content, and read and approved the final version	Wrote the paper	Writing - Review & Editing	YES
3407873	22876272	JRS	PLoS52	conceived and designed the study|interpreted the data|drafted the manuscript|revised the manuscript for intellectual content, and read and approved the final version|is guarantor of the paper	is guarantor of the paper	-	-	NO
3407873	22876272	MB	PLoS52	interpreted the data|revised the manuscript for intellectual content, and read and approved the final version	interpreted the data	Analyzed the data	Formal analysis	YES
3407873	22876272	MB	PLoS52	interpreted the data|revised the manuscript for intellectual content, and read and approved the final version	revised the manuscript for intellectual content, and read and approved the final version	Wrote the paper	Writing - Review & Editing	YES
6352571	30713664	FB	1	Designing of the study	Designing of the study	Conceived and designed the experiments	Methodology	YES
6352571	30713664	HA	1	Designing of the study	Designing of the study	Conceived and designed the experiments	Methodology	YES
4412678	25919374	DYK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4412678	25919374	FX	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4412678	25919374	GJW	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4412678	25919374	JCX	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4412678	25919374	JGZ	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4412678	25919374	LPG	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4412678	25919374	MGZ	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4412678	25919374	MYH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4412678	25919374	PD	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412678	25919374	PD	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412678	25919374	SSH	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4412678	25919374	XG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412678	25919374	XG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412678	25919374	XG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412678	25919374	XG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412678	25919374	YLC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4412678	25919374	YS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4412678	25919374	YYY	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1866246	17520013	MB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1866246	17520013	MB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1866246	17520013	MB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1866246	17520013	MB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1866246	17520013	YM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1866246	17520013	YM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1866246	17520013	YM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1866246	17520013	YM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5701815	29209351	J-HP	2	designed the experiments|performed the experiments and analyzed the data	designed the experiments	Conceived and designed the experiments	Methodology	YES
5701815	29209351	J-HP	2	designed the experiments|performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5701815	29209351	LT	2	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5701815	29209351	SJ	2	designed the experiments|performed the experiments and analyzed the data|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5701815	29209351	SJ	2	designed the experiments|performed the experiments and analyzed the data|wrote the manuscript	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5701815	29209351	SJ	2	designed the experiments|performed the experiments and analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4463951	26069206	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4463951	26069206	HKK	2	conceived and planned the study, and helped in drafting the manuscript	conceived and planned the study, and helped in drafting the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4463951	26069206	IS	2	analyzed xylanase activity	analyzed xylanase activity	Analyzed the data	Formal analysis	YES
4463951	26069206	MK	2	interpreted the data and revised the manuscript	interpreted the data and revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4463951	26069206	TW	2	designed the study, carried out most of the biological studies and statistical analyses, and drafted the manuscript	designed the study, carried out most of the biological studies and statistical analyses, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
3286371	22107883	CKC	2	was responsible for statistical analysis and manuscript preparation	was responsible for statistical analysis and manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3286371	22107883	CLW	2	designed the study and assisted the manuscript preparation	designed the study and assisted the manuscript preparation	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3286371	22107883	CMC	2	were responsible for conducting the study, including subject recruitment, biochemical measurements, and data analysis	were responsible for conducting the study, including subject recruitment, biochemical measurements, and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3286371	22107883	SHF	2	assisted the design of the study and manuscript preparation	assisted the design of the study and manuscript preparation	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3286371	22107883	TRJ	2	designed the study and assisted the manuscript preparation	designed the study and assisted the manuscript preparation	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3286371	22107883	WH	2	were responsible for conducting the study, including subject recruitment, biochemical measurements, and data analysis	were responsible for conducting the study, including subject recruitment, biochemical measurements, and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5559406	28815446	CS	2	contributed in acquiring and analyzing the data and approving the manuscript	contributed in acquiring and analyzing the data and approving the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5559406	28815446	FN	2	contributed in acquiring and analyzing the data and approving the manuscript	contributed in acquiring and analyzing the data and approving the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5559406	28815446	HE	2	contributed in acquiring and analyzing the data and approving the manuscript	contributed in acquiring and analyzing the data and approving the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5559406	28815446	KK	2	contributed in acquiring and analyzing the data and approving the manuscript	contributed in acquiring and analyzing the data and approving the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5559406	28815446	KT	2	contributed in the acquiring, analyzing, and interpreting of the data and drafting, revising, and approving of the manuscript	contributed in the acquiring, analyzing, and interpreting of the data and drafting, revising, and approving of the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5559406	28815446	MH	2	contributed in the conception and design and in the revising and approving of the manuscript and enhancing its intellectual content	contributed in the conception and design and in the revising and approving of the manuscript and enhancing its intellectual content	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5559406	28815446	MI	2	contributed in interpreting the data and drafting, revising, and approving of the manuscript and enhancing its intellectual content	contributed in interpreting the data and drafting, revising, and approving of the manuscript and enhancing its intellectual content	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5559406	28815446	MK	2	contributed in acquiring and analyzing the data and approving the manuscript	contributed in acquiring and analyzing the data and approving the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5559406	28815446	MO	2	contributed in acquiring and analyzing the data and approving the manuscript	contributed in acquiring and analyzing the data and approving the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5559406	28815446	MT	2	contributed in acquiring and analyzing the data and approving the manuscript	contributed in acquiring and analyzing the data and approving the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5559406	28815446	SK	2	contributed in acquiring and analyzing the data and approving the manuscript	contributed in acquiring and analyzing the data and approving the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5559406	28815446	SM	2	contributed in acquiring and analyzing the data and approving the manuscript	contributed in acquiring and analyzing the data and approving the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5559406	28815446	TI	2	contributed in acquiring and analyzing the data and approving the manuscript	contributed in acquiring and analyzing the data and approving the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5559406	28815446	TN	2	contributed in acquiring and analyzing the data and approving the manuscript	contributed in acquiring and analyzing the data and approving the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5559406	28815446	TS	2	contributed in the conception and design and in the revising and approving of the manuscript and enhancing its intellectual content	contributed in the conception and design and in the revising and approving of the manuscript and enhancing its intellectual content	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5559406	28815446	YI	2	contributed in acquiring and analyzing the data and approving the manuscript	contributed in acquiring and analyzing the data and approving the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5559406	28815446	YK	2	contributed in the conception and design	contributed in the conception and design	Conceived and designed the experiments	Conceptualization	YES
5559406	28815446	YT	2	contributed in acquiring and analyzing the data and approving the manuscript	contributed in acquiring and analyzing the data and approving the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5559406	28815446	ZMR	2	contributed in synthesizing the radioligands and approving the manuscript	contributed in synthesizing the radioligands and approving the manuscript	Performed the experiments	Investigation	YES
4412686	25918840	AJ	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4412686	25918840	AJ	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412686	25918840	CM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412686	25918840	CM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412686	25918840	CM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412686	25918840	GT	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412686	25918840	LD	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4412686	25918840	MS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412686	25918840	MS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412686	25918840	MS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6352572	30713669	HN	1	Conception of the work, literature search, experimental studies, data acquisition, data analysis, statistical analysis, manuscript preparation, manuscript editing, and manuscript review	Conception of the work, literature search, experimental studies, data acquisition, data analysis, statistical analysis, manuscript preparation, manuscript editing, and manuscript review	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
6352572	30713669	KI	1	Clinical studies, experimental studies, and data acquisition	Clinical studies, experimental studies, and data acquisition	Performed the experiments	Investigation	YES
6352572	30713669	YS	1	Design of the work, definition of intellectual content, and literature search	Design of the work, definition of intellectual content, and literature search	Conceived and designed the experiments	Formal analysis	YES
6352572	30713669	YT	1	Conception of the work, literature search, experimental studies, data acquisition, data analysis, statistical analysis, manuscript preparation, manuscript editing, and manuscript review	Conception of the work, literature search, experimental studies, data acquisition, data analysis, statistical analysis, manuscript preparation, manuscript editing, and manuscript review	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
3442179	24029401	ALC	2	designed the study|analysed and interpreted the data|drafted the manuscript|critically revised the manuscript for intellectual content	designed the study	Conceived and designed the experiments	Methodology	YES
3442179	24029401	ALC	2	designed the study|analysed and interpreted the data|drafted the manuscript|critically revised the manuscript for intellectual content	analysed and interpreted the data	Analyzed the data	Formal analysis	YES
3442179	24029401	ALC	2	designed the study|analysed and interpreted the data|drafted the manuscript|critically revised the manuscript for intellectual content	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
3442179	24029401	ALC	2	designed the study|analysed and interpreted the data|drafted the manuscript|critically revised the manuscript for intellectual content	critically revised the manuscript for intellectual content	Wrote the paper	Writing - Review & Editing	YES
3442179	24029401	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
3442179	24029401	FN	2	conceived the study|designed the study|analysed and interpreted the data|critically revised the manuscript for intellectual content	conceived the study	Conceived and designed the experiments	Conceptualization	YES
3442179	24029401	FN	2	conceived the study|designed the study|analysed and interpreted the data|critically revised the manuscript for intellectual content	designed the study	Conceived and designed the experiments	Methodology	YES
3442179	24029401	FN	2	conceived the study|designed the study|analysed and interpreted the data|critically revised the manuscript for intellectual content	analysed and interpreted the data	Analyzed the data	Formal analysis	YES
3442179	24029401	FN	2	conceived the study|designed the study|analysed and interpreted the data|critically revised the manuscript for intellectual content	critically revised the manuscript for intellectual content	Wrote the paper	Writing - Review & Editing	YES
3442179	24029401	JW	2	designed the study|drafted the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
3442179	24029401	JW	2	designed the study|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
3442179	24029401	MKP	2	designed the study|drafted the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
3442179	24029401	MKP	2	designed the study|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
3442179	24029401	MP	2	designed the study|drafted the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
3442179	24029401	MP	2	designed the study|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
3442179	24029401	MvV	2	designed the study|critically revised the manuscript for intellectual content	designed the study	Conceived and designed the experiments	Methodology	YES
3442179	24029401	MvV	2	designed the study|critically revised the manuscript for intellectual content	critically revised the manuscript for intellectual content	Wrote the paper	Writing - Review & Editing	YES
3442179	24029401	RM	2	conceived the study|designed the study|analysed and interpreted the data|drafted the manuscript|critically revised the manuscript for intellectual content|is guarantor of the paper	conceived the study	Conceived and designed the experiments	Conceptualization	YES
3442179	24029401	RM	2	conceived the study|designed the study|analysed and interpreted the data|drafted the manuscript|critically revised the manuscript for intellectual content|is guarantor of the paper	designed the study	Conceived and designed the experiments	Methodology	YES
3442179	24029401	RM	2	conceived the study|designed the study|analysed and interpreted the data|drafted the manuscript|critically revised the manuscript for intellectual content|is guarantor of the paper	analysed and interpreted the data	Analyzed the data	Formal analysis	YES
3442179	24029401	RM	2	conceived the study|designed the study|analysed and interpreted the data|drafted the manuscript|critically revised the manuscript for intellectual content|is guarantor of the paper	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
3442179	24029401	RM	2	conceived the study|designed the study|analysed and interpreted the data|drafted the manuscript|critically revised the manuscript for intellectual content|is guarantor of the paper	critically revised the manuscript for intellectual content	Wrote the paper	Writing - Review & Editing	YES
3442179	24029401	RM	2	conceived the study|designed the study|analysed and interpreted the data|drafted the manuscript|critically revised the manuscript for intellectual content|is guarantor of the paper	is guarantor of the paper	-	-	NO
3442179	24029401	SJL	2	analysed and interpreted the data|critically revised the manuscript for intellectual content	analysed and interpreted the data	Analyzed the data	Formal analysis	YES
3442179	24029401	SJL	2	analysed and interpreted the data|critically revised the manuscript for intellectual content	critically revised the manuscript for intellectual content	Wrote the paper	Writing - Review & Editing	YES
3442179	24029401	VIC	2	designed the study|analysed and interpreted the data|drafted the manuscript|critically revised the manuscript for intellectual content	designed the study	Conceived and designed the experiments	Methodology	YES
3442179	24029401	VIC	2	designed the study|analysed and interpreted the data|drafted the manuscript|critically revised the manuscript for intellectual content	analysed and interpreted the data	Analyzed the data	Formal analysis	YES
3442179	24029401	VIC	2	designed the study|analysed and interpreted the data|drafted the manuscript|critically revised the manuscript for intellectual content	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
3442179	24029401	VIC	2	designed the study|analysed and interpreted the data|drafted the manuscript|critically revised the manuscript for intellectual content	critically revised the manuscript for intellectual content	Wrote the paper	Writing - Review & Editing	YES
5701927	29209349	AV	2	prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5701927	29209349	All authors	2	have read and approved the manuscript for publication	have read and approved the manuscript for publication	-	-	NO
5701927	29209349	HM	2	designed the experiments|prepared the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5701927	29209349	HM	2	designed the experiments|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5701927	29209349	SC	2	designed the experiments|prepared the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5701927	29209349	SC	2	designed the experiments|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5701927	29209349	YC	2	conducted the experiments and analyzed the results|prepared the manuscript	conducted the experiments and analyzed the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5701927	29209349	YC	2	conducted the experiments and analyzed the results|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5701927	29209349	ZW	2	conducted the experiments and analyzed the results|prepared the manuscript	conducted the experiments and analyzed the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5701927	29209349	ZW	2	conducted the experiments and analyzed the results|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
3287968	22309475	AB	2	participated in the data collection process	participated in the data collection process	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
3287968	22309475	BK	2	supervised the analyses of data and helped to draft the manuscript	supervised the analyses of data and helped to draft the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Supervision|Writing - Original Draft	YES
3287968	22309475	FR	2	participated in the design of the study and managed the data collection process	participated in the design of the study and managed the data collection process	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Data curation|Investigation|Methodology	YES
3287968	22309475	JP	2	participated in the data collection process	participated in the data collection process	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
3287968	22309475	JV	2	participated in the data collection process	participated in the data collection process	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
3287968	22309475	MM	2	participated in the data collection process	participated in the data collection process	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
3287968	22309475	PT	2	participated in the data collection process	participated in the data collection process	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
3287968	22309475	RB	2	participated in the design of the study, managed the data collection process, conducted the analysis and drafted the manuscript	participated in the design of the study, managed the data collection process, conducted the analysis and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
3287968	22309475	TR	2	supervised the analyses of data and helped to draft the manuscript	supervised the analyses of data and helped to draft the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Supervision|Writing - Original Draft	YES
3287968	22309475	XI	2	participated in the design of the study and managed the data collection process	participated in the design of the study and managed the data collection process	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Data curation|Investigation|Methodology	YES
4412704	25919393	ACK	PLoS5	Analyzed the data|Provided conceptual contribution to the work and critical revision of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4412704	25919393	ACK	PLoS5	Analyzed the data|Provided conceptual contribution to the work and critical revision of the manuscript	Provided conceptual contribution to the work and critical revision of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
4412704	25919393	CDP	PLoS5	Provided conceptual contribution to the work and critical revision of the manuscript	Provided conceptual contribution to the work and critical revision of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
4412704	25919393	CEK	PLoS5	Performed the experiments|Provided conceptual contribution to the work and critical revision of the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4412704	25919393	CEK	PLoS5	Performed the experiments|Provided conceptual contribution to the work and critical revision of the manuscript	Provided conceptual contribution to the work and critical revision of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
4412704	25919393	DFN	PLoS5	Conceived and designed the experiments|Provided conceptual contribution to the work and critical revision of the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412704	25919393	DFN	PLoS5	Conceived and designed the experiments|Provided conceptual contribution to the work and critical revision of the manuscript	Provided conceptual contribution to the work and critical revision of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
4412704	25919393	EME	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412704	25919393	EME	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412704	25919393	EME	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412704	25919393	EME	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412704	25919393	FMH	PLoS5	Conceived and designed the experiments|Provided conceptual contribution to the work and critical revision of the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412704	25919393	FMH	PLoS5	Conceived and designed the experiments|Provided conceptual contribution to the work and critical revision of the manuscript	Provided conceptual contribution to the work and critical revision of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
4412704	25919393	LL	PLoS5	Provided conceptual contribution to the work and critical revision of the manuscript	Provided conceptual contribution to the work and critical revision of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
4412704	25919393	SJH	PLoS5	Performed the experiments|Provided conceptual contribution to the work and critical revision of the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4412704	25919393	SJH	PLoS5	Performed the experiments|Provided conceptual contribution to the work and critical revision of the manuscript	Provided conceptual contribution to the work and critical revision of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
4412704	25919393	TL	PLoS5	Analyzed the data|Provided conceptual contribution to the work and critical revision of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4412704	25919393	TL	PLoS5	Analyzed the data|Provided conceptual contribution to the work and critical revision of the manuscript	Provided conceptual contribution to the work and critical revision of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5559839	28814268	AP	2	conceived and designed the genetic study of mastitis in chios sheep and secured substantial funding|performed data collection, phenotyping, dna extractions and genetic parameter analysis|collated and edited the genotyping data and performed the genomic analysis|performed the pathway and the tfbs analyses|extracted and annotated the re-sequencing data of the hapmap sheep|interpreted these results|wrote the manuscript	conceived and designed the genetic study of mastitis in chios sheep and secured substantial funding	Conceived and designed the experiments|Performed the experiments	Conceptualization|Funding acquisition|Investigation|Methodology	YES
5559839	28814268	AP	2	conceived and designed the genetic study of mastitis in chios sheep and secured substantial funding|performed data collection, phenotyping, dna extractions and genetic parameter analysis|collated and edited the genotyping data and performed the genomic analysis|performed the pathway and the tfbs analyses|extracted and annotated the re-sequencing data of the hapmap sheep|interpreted these results|wrote the manuscript	performed data collection, phenotyping, dna extractions and genetic parameter analysis	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5559839	28814268	AP	2	conceived and designed the genetic study of mastitis in chios sheep and secured substantial funding|performed data collection, phenotyping, dna extractions and genetic parameter analysis|collated and edited the genotyping data and performed the genomic analysis|performed the pathway and the tfbs analyses|extracted and annotated the re-sequencing data of the hapmap sheep|interpreted these results|wrote the manuscript	collated and edited the genotyping data and performed the genomic analysis	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Formal analysis|Investigation|Writing - Review & Editing	YES
5559839	28814268	AP	2	conceived and designed the genetic study of mastitis in chios sheep and secured substantial funding|performed data collection, phenotyping, dna extractions and genetic parameter analysis|collated and edited the genotyping data and performed the genomic analysis|performed the pathway and the tfbs analyses|extracted and annotated the re-sequencing data of the hapmap sheep|interpreted these results|wrote the manuscript	performed the pathway and the tfbs analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5559839	28814268	AP	2	conceived and designed the genetic study of mastitis in chios sheep and secured substantial funding|performed data collection, phenotyping, dna extractions and genetic parameter analysis|collated and edited the genotyping data and performed the genomic analysis|performed the pathway and the tfbs analyses|extracted and annotated the re-sequencing data of the hapmap sheep|interpreted these results|wrote the manuscript	extracted and annotated the re-sequencing data of the hapmap sheep	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5559839	28814268	AP	2	conceived and designed the genetic study of mastitis in chios sheep and secured substantial funding|performed data collection, phenotyping, dna extractions and genetic parameter analysis|collated and edited the genotyping data and performed the genomic analysis|performed the pathway and the tfbs analyses|extracted and annotated the re-sequencing data of the hapmap sheep|interpreted these results|wrote the manuscript	interpreted these results	Analyzed the data	Formal analysis	YES
5559839	28814268	AP	2	conceived and designed the genetic study of mastitis in chios sheep and secured substantial funding|performed data collection, phenotyping, dna extractions and genetic parameter analysis|collated and edited the genotyping data and performed the genomic analysis|performed the pathway and the tfbs analyses|extracted and annotated the re-sequencing data of the hapmap sheep|interpreted these results|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5559839	28814268	All	2	other co-authors provided manuscript editing and feedback	other co-authors provided manuscript editing and feedback	Wrote the paper	Writing - Review & Editing	YES
5559839	28814268	DAH	2	secured the substantial funding	secured the substantial funding	-	Funding acquisition	YES
5559839	28814268	DH	2	interpreted these results	interpreted these results	Analyzed the data	Formal analysis	YES
5559839	28814268	ELC	2	created the sheep transcriptomic atlas and analysed the gene expression data of the sheep atlas and the milk transcriptome	created the sheep transcriptomic atlas and analysed the gene expression data of the sheep atlas and the milk transcriptome	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5559839	28814268	GA	2	conceived and designed the genetic study of mastitis in chios sheep and secured substantial funding|interpreted these results	conceived and designed the genetic study of mastitis in chios sheep and secured substantial funding	Conceived and designed the experiments|Performed the experiments	Conceptualization|Funding acquisition|Investigation|Methodology	YES
5559839	28814268	GA	2	conceived and designed the genetic study of mastitis in chios sheep and secured substantial funding|interpreted these results	interpreted these results	Analyzed the data	Formal analysis	YES
5559839	28814268	GBa	2	conceived and designed the genetic study of mastitis in chios sheep and secured substantial funding|performed data collection, phenotyping, dna extractions and genetic parameter analysis|collated and edited the genotyping data and performed the genomic analysis|interpreted these results|wrote the manuscript	conceived and designed the genetic study of mastitis in chios sheep and secured substantial funding	Conceived and designed the experiments|Performed the experiments	Conceptualization|Funding acquisition|Investigation|Methodology	YES
5559839	28814268	GBa	2	conceived and designed the genetic study of mastitis in chios sheep and secured substantial funding|performed data collection, phenotyping, dna extractions and genetic parameter analysis|collated and edited the genotyping data and performed the genomic analysis|interpreted these results|wrote the manuscript	performed data collection, phenotyping, dna extractions and genetic parameter analysis	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5559839	28814268	GBa	2	conceived and designed the genetic study of mastitis in chios sheep and secured substantial funding|performed data collection, phenotyping, dna extractions and genetic parameter analysis|collated and edited the genotyping data and performed the genomic analysis|interpreted these results|wrote the manuscript	collated and edited the genotyping data and performed the genomic analysis	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Formal analysis|Investigation|Writing - Review & Editing	YES
5559839	28814268	GBa	2	conceived and designed the genetic study of mastitis in chios sheep and secured substantial funding|performed data collection, phenotyping, dna extractions and genetic parameter analysis|collated and edited the genotyping data and performed the genomic analysis|interpreted these results|wrote the manuscript	interpreted these results	Analyzed the data	Formal analysis	YES
5559839	28814268	GBa	2	conceived and designed the genetic study of mastitis in chios sheep and secured substantial funding|performed data collection, phenotyping, dna extractions and genetic parameter analysis|collated and edited the genotyping data and performed the genomic analysis|interpreted these results|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5559839	28814268	GBr	2	performed data collection, phenotyping, dna extractions and genetic parameter analysis	performed data collection, phenotyping, dna extractions and genetic parameter analysis	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5559839	28814268	GS	2	performed the pathway and the tfbs analyses|extracted and annotated the re-sequencing data of the hapmap sheep	performed the pathway and the tfbs analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5559839	28814268	GS	2	performed the pathway and the tfbs analyses|extracted and annotated the re-sequencing data of the hapmap sheep	extracted and annotated the re-sequencing data of the hapmap sheep	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5559839	28814268	JS	2	performed the pathway and the tfbs analyses	performed the pathway and the tfbs analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5559839	28814268	MBM	2	generated the bmdm lps time-course dataset for the transcriptomic atlas	generated the bmdm lps time-course dataset for the transcriptomic atlas	Performed the experiments	Investigation	YES
5559839	28814268	SJB	2	created the sheep transcriptomic atlas and analysed the gene expression data of the sheep atlas and the milk transcriptome|extracted and annotated the re-sequencing data of the hapmap sheep	created the sheep transcriptomic atlas and analysed the gene expression data of the sheep atlas and the milk transcriptome	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5559839	28814268	SJB	2	created the sheep transcriptomic atlas and analysed the gene expression data of the sheep atlas and the milk transcriptome|extracted and annotated the re-sequencing data of the hapmap sheep	extracted and annotated the re-sequencing data of the hapmap sheep	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
4467805	26061774	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4467805	26061774	KN	2	conceived the study, participated in its design, drafted the manuscript	conceived the study, participated in its design, drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
4467805	26061774	KO	2	isolated bacterial and yeast strains from the kombucha culture	isolated bacterial and yeast strains from the kombucha culture	Performed the experiments	Investigation	YES
4467805	26061774	OL	2	carried out the molecular genetic studies	carried out the molecular genetic studies	Performed the experiments	Investigation	YES
4467805	26061774	PO	2	performed the sequence alignment	performed the sequence alignment	Performed the experiments	Investigation	YES
4467805	26061774	RO	2	performed the bioinformatics analysis and helped to draft the manuscript	performed the bioinformatics analysis and helped to draft the manuscript	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4467805	26061774	SS	2	carried out the cslm observations	carried out the cslm observations	Performed the experiments	Investigation	YES
4467805	26061774	VJ-P	2	participated in the design of the study	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
4467805	26061774	ZI	2	coordinated the study, helped to draft the manuscript and designed figures	coordinated the study, helped to draft the manuscript and designed figures	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Visualization|Writing - Original Draft	YES
5559408	28815478	BS	PLoS52	designed the study and wrote the protocol	designed the study and wrote the protocol	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5559408	28815478	CPF	PLoS52	designed the study and wrote the protocol|performed the pet studies|analysed the data|wrote the first draft of the manuscript	designed the study and wrote the protocol	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5559408	28815478	CPF	PLoS52	designed the study and wrote the protocol|performed the pet studies|analysed the data|wrote the first draft of the manuscript	performed the pet studies	Performed the experiments	Investigation	YES
5559408	28815478	CPF	PLoS52	designed the study and wrote the protocol|performed the pet studies|analysed the data|wrote the first draft of the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
5559408	28815478	CPF	PLoS52	designed the study and wrote the protocol|performed the pet studies|analysed the data|wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
5559408	28815478	ERK	PLoS52	analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
5559408	28815478	FMM	PLoS52	designed the study and wrote the protocol	designed the study and wrote the protocol	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5559408	28815478	GB	PLoS52	designed the study and wrote the protocol	designed the study and wrote the protocol	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5559408	28815478	GS	PLoS52	performed the pet studies	performed the pet studies	Performed the experiments	Investigation	YES
5559408	28815478	JCT	PLoS52	designed the study and wrote the protocol	designed the study and wrote the protocol	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5559408	28815478	KJL	PLoS52	designed the study and wrote the protocol|analysed the data|wrote the first draft of the manuscript	designed the study and wrote the protocol	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5559408	28815478	KJL	PLoS52	designed the study and wrote the protocol|analysed the data|wrote the first draft of the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
5559408	28815478	KJL	PLoS52	designed the study and wrote the protocol|analysed the data|wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
5559408	28815478	NG	PLoS52	analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
5559408	28815478	NJS	PLoS52	designed the study and wrote the protocol	designed the study and wrote the protocol	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5559408	28815478	NLA	PLoS52	designed the study and wrote the protocol|wrote the first draft of the manuscript	designed the study and wrote the protocol	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5559408	28815478	NLA	PLoS52	designed the study and wrote the protocol|wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
5559408	28815478	PB	PLoS52	designed the study and wrote the protocol	designed the study and wrote the protocol	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
1866360	17505547	AB	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1866360	17505547	AM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1866360	17505547	AM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1866360	17505547	BD	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1866360	17505547	BD	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1866360	17505547	BD	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1866360	17505547	CS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1866360	17505547	CS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1866360	17505547	CS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1866360	17505547	DC	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1866360	17505547	DC	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1866360	17505547	DC	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1866360	17505547	DC	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1866360	17505547	EL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Made useful comments on the paper	Performed the experiments	Performed the experiments	Investigation	YES
1866360	17505547	EL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Made useful comments on the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1866360	17505547	EL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Made useful comments on the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1866360	17505547	EL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Made useful comments on the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1866360	17505547	EL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Made useful comments on the paper	Made useful comments on the paper	-	-	NO
1866360	17505547	JC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1866360	17505547	JC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1866360	17505547	LJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Decided to submit the work for publication	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1866360	17505547	LJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Decided to submit the work for publication	Performed the experiments	Performed the experiments	Investigation	YES
1866360	17505547	LJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Decided to submit the work for publication	Analyzed the data	Analyzed the data	Formal analysis	YES
1866360	17505547	LJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Decided to submit the work for publication	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1866360	17505547	LJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Decided to submit the work for publication	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1866360	17505547	LJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Decided to submit the work for publication	Decided to submit the work for publication	-	-	NO
1866360	17505547	MT	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1866360	17505547	MT	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1866360	17505547	MT	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1866360	17505547	RL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1866360	17505547	RL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1866360	17505547	RL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1866360	17505547	SE	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1866360	17505547	SK	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1866360	17505547	SK	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
6352573	30713670	QZL	1	Writing the manuscript	Writing the manuscript	Wrote the paper	Writing - Original Draft	YES
6352573	30713670	XL	1	Writing the manuscript	Writing the manuscript	Wrote the paper	Writing - Original Draft	YES
3292952	22293241	DH	2	as post-graduate student, was responsible for recruiting the study participants, applying the study intervention, recording the data and writing the first draft of the manuscript|in the laboratory skills, helped with the statistical analyses and refined the final version of the manuscript	as post-graduate student, was responsible for recruiting the study participants, applying the study intervention, recording the data and writing the first draft of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3292952	22293241	DH	2	as post-graduate student, was responsible for recruiting the study participants, applying the study intervention, recording the data and writing the first draft of the manuscript|in the laboratory skills, helped with the statistical analyses and refined the final version of the manuscript	in the laboratory skills, helped with the statistical analyses and refined the final version of the manuscript	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4600487	26491665	Fei Jiang	2	contributed equally to this work	contributed equally to this work	-	-	NO
4600487	26491665	Jie Ma	2	contributed equally to this work	contributed equally to this work	-	-	NO
4412705	25919659	CMM	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412705	25919659	CMM	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412705	25919659	JAH	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412705	25919659	JAH	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412705	25919659	RCB	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412705	25919659	RCB	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412705	25919659	RGT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412705	25919659	RGT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412705	25919659	RGT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5701936	29209342	AS	PLoS52	designed this study|performed the research and analyzed the data|generated plasmids and established mutant lines|wrote the paper	designed this study	Conceived and designed the experiments	Methodology	YES
5701936	29209342	AS	PLoS52	designed this study|performed the research and analyzed the data|generated plasmids and established mutant lines|wrote the paper	performed the research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5701936	29209342	AS	PLoS52	designed this study|performed the research and analyzed the data|generated plasmids and established mutant lines|wrote the paper	generated plasmids and established mutant lines	Performed the experiments	Investigation	YES
5701936	29209342	AS	PLoS52	designed this study|performed the research and analyzed the data|generated plasmids and established mutant lines|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5701936	29209342	MH	PLoS52	designed this study|wrote the paper|directed the project	designed this study	Conceived and designed the experiments	Methodology	YES
5701936	29209342	MH	PLoS52	designed this study|wrote the paper|directed the project	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5701936	29209342	MH	PLoS52	designed this study|wrote the paper|directed the project	directed the project	-	Supervision	YES
5701936	29209342	MJ	PLoS52	generated plasmids and established mutant lines	generated plasmids and established mutant lines	Performed the experiments	Investigation	YES
3293068	22257640	DRK	2	were responsible for the study design, coordination of the study, and oversight of data collection and analysis	were responsible for the study design, coordination of the study, and oversight of data collection and analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology|Project administration|Supervision	YES
3293068	22257640	DSK	2	were responsible for the study design, coordination of the study, and oversight of data collection and analysis	were responsible for the study design, coordination of the study, and oversight of data collection and analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology|Project administration|Supervision	YES
3293068	22257640	RJB	2	assisted in manuscript preparation	assisted in manuscript preparation	Wrote the paper	Writing - Original Draft	YES
3293068	22257640	SF	2	were responsible for the study design, coordination of the study, and oversight of data collection and analysis	were responsible for the study design, coordination of the study, and oversight of data collection and analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology|Project administration|Supervision	YES
5560283	28819936	All authors	2	reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5560283	28819936	BK	2	carried out the data acquisition	carried out the data acquisition	Performed the experiments	Investigation	YES
5560283	28819936	FWBvL	2	are responsible for the study concept and study design|prepared in the manuscript	are responsible for the study concept and study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5560283	28819936	FWBvL	2	are responsible for the study concept and study design|prepared in the manuscript	prepared in the manuscript	Wrote the paper	Writing - Original Draft	YES
5560283	28819936	GHK	2	are responsible for the study concept and study design|carried out the data acquisition|are performed the quality control of data and algorithms, data analysis and interpretation, and statistical analysis|prepared in the manuscript	are responsible for the study concept and study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5560283	28819936	GHK	2	are responsible for the study concept and study design|carried out the data acquisition|are performed the quality control of data and algorithms, data analysis and interpretation, and statistical analysis|prepared in the manuscript	carried out the data acquisition	Performed the experiments	Investigation	YES
5560283	28819936	GHK	2	are responsible for the study concept and study design|carried out the data acquisition|are performed the quality control of data and algorithms, data analysis and interpretation, and statistical analysis|prepared in the manuscript	are performed the quality control of data and algorithms, data analysis and interpretation, and statistical analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Software|Validation	YES
5560283	28819936	GHK	2	are responsible for the study concept and study design|carried out the data acquisition|are performed the quality control of data and algorithms, data analysis and interpretation, and statistical analysis|prepared in the manuscript	prepared in the manuscript	Wrote the paper	Writing - Original Draft	YES
5560283	28819936	NSvdB	2	are responsible for the study concept and study design|carried out the data acquisition|are performed the quality control of data and algorithms, data analysis and interpretation, and statistical analysis|prepared in the manuscript	are responsible for the study concept and study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5560283	28819936	NSvdB	2	are responsible for the study concept and study design|carried out the data acquisition|are performed the quality control of data and algorithms, data analysis and interpretation, and statistical analysis|prepared in the manuscript	carried out the data acquisition	Performed the experiments	Investigation	YES
5560283	28819936	NSvdB	2	are responsible for the study concept and study design|carried out the data acquisition|are performed the quality control of data and algorithms, data analysis and interpretation, and statistical analysis|prepared in the manuscript	are performed the quality control of data and algorithms, data analysis and interpretation, and statistical analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Software|Validation	YES
5560283	28819936	NSvdB	2	are responsible for the study concept and study design|carried out the data acquisition|are performed the quality control of data and algorithms, data analysis and interpretation, and statistical analysis|prepared in the manuscript	prepared in the manuscript	Wrote the paper	Writing - Original Draft	YES
5560283	28819936	TE	2	carried out the data acquisition	carried out the data acquisition	Performed the experiments	Investigation	YES
5560283	28819936	WMCK	2	carried out the data acquisition	carried out the data acquisition	Performed the experiments	Investigation	YES
6352575	30713668	XJS	1	Study design	Study design	Conceived and designed the experiments	Methodology	YES
3316133	22397703	AJW	2	were co-authors, assisting with data collection and data analysis	were co-authors, assisting with data collection and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3316133	22397703	AMG	2	were co-authors, assisting with data collection and data analysis	were co-authors, assisting with data collection and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3316133	22397703	DMN	2	were co-authors, assisting with data collection and data analysis	were co-authors, assisting with data collection and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3316133	22397703	DRW	2	were co-authors, assisting with data collection and data analysis	were co-authors, assisting with data collection and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3316133	22397703	GTM	2	were co-authors, assisting with data collection and data analysis	were co-authors, assisting with data collection and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3316133	22397703	JRH	2	was the primary investigator, designed study, supervised all study recruitment, data/specimen analysis, statistical analysis and manuscript preparation	was the primary investigator, designed study, supervised all study recruitment, data/specimen analysis, statistical analysis and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Supervision|Writing - Original Draft	YES
3316133	22397703	MSF	2	helped drafting the drafting the manuscript	helped drafting the drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
3316133	22397703	MWH	2	were co-authors, assisting with data collection and data analysis	were co-authors, assisting with data collection and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3316133	22397703	NSE	2	were co-authors, assisting with data collection and data analysis	were co-authors, assisting with data collection and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3316133	22397703	WPM	2	were co-authors, assisting with data collection and data analysis	were co-authors, assisting with data collection and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4412707	25919689	K. Namba	PLoS5	Performed the experiments|Analyzed the data|Critical revision of the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4412707	25919689	K. Namba	PLoS5	Performed the experiments|Analyzed the data|Critical revision of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4412707	25919689	K. Namba	PLoS5	Performed the experiments|Analyzed the data|Critical revision of the manuscript	Critical revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4412707	25919689	K. Noda	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Critical revision of the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4412707	25919689	K. Noda	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Critical revision of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4412707	25919689	K. Noda	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Critical revision of the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412707	25919689	K. Noda	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Critical revision of the manuscript	Critical revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4412707	25919689	MS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Statistical analysis	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412707	25919689	MS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Statistical analysis	Analyzed the data	Analyzed the data	Formal analysis	YES
4412707	25919689	MS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Statistical analysis	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412707	25919689	MS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Statistical analysis	Statistical analysis	Analyzed the data	Formal analysis	YES
4412707	25919689	SI	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Critical revision of the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412707	25919689	SI	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Critical revision of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4412707	25919689	SI	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Critical revision of the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412707	25919689	SI	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Critical revision of the manuscript	Critical revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4412707	25919689	SM	PLoS5	Performed the experiments|Analyzed the data|Critical revision of the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4412707	25919689	SM	PLoS5	Performed the experiments|Analyzed the data|Critical revision of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4412707	25919689	SM	PLoS5	Performed the experiments|Analyzed the data|Critical revision of the manuscript	Critical revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4412707	25919689	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412707	25919689	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412707	25919689	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412707	25919689	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412707	25919689	WS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Critical revision of the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412707	25919689	WS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Critical revision of the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4412707	25919689	WS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Critical revision of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4412707	25919689	WS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Critical revision of the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412707	25919689	WS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Critical revision of the manuscript	Critical revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4412707	25919689	YH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412707	25919689	YH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412707	25919689	YH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4467806	26061773	AK	2	participated in the design of the study and helped to draft the manuscript	participated in the design of the study and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4467806	26061773	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4467806	26061773	KW	2	designed the study and wrote the manuscript	designed the study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4467806	26061773	MM	2	carried out the reactor operation and molecular genetic analyses	carried out the reactor operation and molecular genetic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
1867856	17520026	JA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1867856	17520026	JA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1867856	17520026	JA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1867856	17520026	JC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1867856	17520026	JC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1867856	17520026	JC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1867856	17520026	JC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1867856	17520026	JS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1867856	17520026	JS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1867856	17520026	MR	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1867856	17520026	MS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1867856	17520026	MW	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1867856	17520026	MW	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5702007	29209355	AG	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5702007	29209355	AG	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5702007	29209355	JF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5702007	29209355	JF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
5702007	29209355	JF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5702007	29209355	JF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5702007	29209355	LZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5702007	29209355	SS	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5702007	29209355	SS	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5702007	29209355	YB	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5702007	29209355	YB	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5559859	28814280	All authors	2	were involved in methodological development	were involved in methodological development	Performed the experiments	Methodology	YES
5559859	28814280	SH	2	conducted programming and numerical study	conducted programming and numerical study	Performed the experiments|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Software	YES
6352576	30713667	CA	1	Patient management	Patient management	-	-	NO
6352576	30713667	JG	1	Patient management	Patient management	-	-	NO
5561746	28822108	All authors	2	participated in the study planning, data analysis, and drafting of the manuscript and approved the final version	participated in the study planning, data analysis, and drafting of the manuscript and approved the final version	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3325889	22448911	All authors	2	were responsible for the experimental design, data collection, statistical analysis and preparation of the manuscript|worked read and approved the final manuscript	were responsible for the experimental design, data collection, statistical analysis and preparation of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
3325889	22448911	All authors	2	were responsible for the experimental design, data collection, statistical analysis and preparation of the manuscript|worked read and approved the final manuscript	worked read and approved the final manuscript	Performed the experiments|Wrote the paper	Writing - Review & Editing	YES
4412708	25919023	ELT	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412708	25919023	ELT	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412708	25919023	ELT	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412708	25919023	ELT	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412708	25919023	FB	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412708	25919023	FB	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412708	25919023	FB	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412708	25919023	FB	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412708	25919023	JAM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412708	25919023	JAM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412708	25919023	JAM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412708	25919023	JAM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412708	25919023	LP	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412708	25919023	LP	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412708	25919023	LP	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412708	25919023	LP	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412708	25919023	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412708	25919023	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412708	25919023	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412708	25919023	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412708	25919023	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412708	25919023	MMR	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412708	25919023	MMR	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412708	25919023	MMR	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412708	25919023	MMR	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3331813	22444601	Both authors	2	gave suggestions, read the manuscript carefully, fully agreed on its content and approved its final version	gave suggestions, read the manuscript carefully, fully agreed on its content and approved its final version	-	-	NO
3331813	22444601	CB	2	conceived the idea of the study, participated in the design of the study, analysis of data, drafted the first version of the manuscript and participated in finalizing the manuscript	conceived the idea of the study, participated in the design of the study, analysis of data, drafted the first version of the manuscript and participated in finalizing the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
3331813	22444601	EH	2	participated in the design of the study, and had the major responsibility of recruiting subjects and coordinating the data collection and analysis of the data|participated in developing the manuscript, discussing the findings and in finalizing the manuscript	participated in the design of the study, and had the major responsibility of recruiting subjects and coordinating the data collection and analysis of the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology|Project administration	YES
3331813	22444601	EH	2	participated in the design of the study, and had the major responsibility of recruiting subjects and coordinating the data collection and analysis of the data|participated in developing the manuscript, discussing the findings and in finalizing the manuscript	participated in developing the manuscript, discussing the findings and in finalizing the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4469597	26080793	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4469597	26080793	BL	2	wrote the manuscript assisted by all co-authors	wrote the manuscript assisted by all co-authors	Wrote the paper	Writing - Original Draft	YES
4469597	26080793	BZM	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
4469597	26080793	JDG	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
4469597	26080793	JFL	2	were committed to all the experiments	were committed to all the experiments	-	-	NO
4469597	26080793	LYW	2	wrote the manuscript assisted by all co-authors|designed the study|on statistical analysis and in the discussion on the interpretation of the data	wrote the manuscript assisted by all co-authors	Wrote the paper	Writing - Original Draft	YES
4469597	26080793	LYW	2	wrote the manuscript assisted by all co-authors|designed the study|on statistical analysis and in the discussion on the interpretation of the data	designed the study	Conceived and designed the experiments	Methodology	YES
4469597	26080793	LYW	2	wrote the manuscript assisted by all co-authors|designed the study|on statistical analysis and in the discussion on the interpretation of the data	on statistical analysis and in the discussion on the interpretation of the data	Analyzed the data	Formal analysis	YES
4469597	26080793	RGC	2	joint research fund	joint research fund	-	-	NO
4469597	26080793	SZY	2	were committed to all the experiments	were committed to all the experiments	-	-	NO
1867857	17520028	AL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1867857	17520028	AL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1867857	17520028	AL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1867857	17520028	AL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1867857	17520028	BD	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1867857	17520028	BD	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1867857	17520028	BD	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1867857	17520028	CK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1867857	17520028	CS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1867857	17520028	CS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1867857	17520028	CS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1867857	17520028	CS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1867857	17520028	CS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1867857	17520028	FM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1867857	17520028	FM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1867857	17520028	GS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1867857	17520028	GS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1867857	17520028	GT	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1867857	17520028	GT	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1867857	17520028	LB	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1867857	17520028	MG	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1867857	17520028	MG	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1867857	17520028	MG	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1867857	17520028	MG	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1867857	17520028	MG	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1867857	17520028	MG	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1867857	17520028	NC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1867857	17520028	PL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1867857	17520028	SF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1867857	17520028	SF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1867857	17520028	SF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1867857	17520028	SF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1867857	17520028	SF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6463440	30950416	AM	1	Study design, concept and definition	Study design, concept and definition	Conceived and designed the experiments	Conceptualization|Methodology	YES
6463440	30950416	DT	1	Study design, concept and definition	Study design, concept and definition	Conceived and designed the experiments	Conceptualization|Methodology	YES
6463440	30950416	EL	1	Study design, concept and definition	Study design, concept and definition	Conceived and designed the experiments	Conceptualization|Methodology	YES
6463440	30950416	ERC	1	Study design, concept and definition	Study design, concept and definition	Conceived and designed the experiments	Conceptualization|Methodology	YES
6463440	30950416	FS	1	Study design, concept and definition	Study design, concept and definition	Conceived and designed the experiments	Conceptualization|Methodology	YES
6463440	30950416	MCV	1	Study design, concept and definition	Study design, concept and definition	Conceived and designed the experiments	Conceptualization|Methodology	YES
6463440	30950416	MV	1	Study design, concept and definition	Study design, concept and definition	Conceived and designed the experiments	Conceptualization|Methodology	YES
6463440	30950416	SMN	1	Study design, concept and definition	Study design, concept and definition	Conceived and designed the experiments	Conceptualization|Methodology	YES
5561763	28822101	All authors	2	participated in the study planning, data analysis, and drafting of the manuscript and approved the final version	participated in the study planning, data analysis, and drafting of the manuscript and approved the final version	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5702011	29209335	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5702011	29209335	M-XW	2	participated in sample preparing, treating, collecting, total rna extracting and manuscript revise	participated in sample preparing, treating, collecting, total rna extracting and manuscript revise	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5702011	29209335	PM	2	participated in sample preparing, treating, collecting, total rna extracting and manuscript revise	participated in sample preparing, treating, collecting, total rna extracting and manuscript revise	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5702011	29209335	X-RM	2	conceived this study, designed the experimental plan, analysed data, drafted and revised the manuscript	conceived this study, designed the experimental plan, analysed data, drafted and revised the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5702011	29209335	XT	2	conceived this study, designed the experimental plan, analysed data, drafted and revised the manuscript	conceived this study, designed the experimental plan, analysed data, drafted and revised the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5702011	29209335	Y-FF	2	participated in sample preparing, treating, collecting, total rna extracting and manuscript revise	participated in sample preparing, treating, collecting, total rna extracting and manuscript revise	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5702011	29209335	YD	2	participated in sample preparing, treating, collecting, total rna extracting and manuscript revise	participated in sample preparing, treating, collecting, total rna extracting and manuscript revise	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5702011	29209335	YW	2	participated in data analyses and manuscript revise	participated in data analyses and manuscript revise	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5561555	28818039	AK	2	designed the study|performed the bioinformatics data analyses|performed the cell culture work and qrt-pcr experiments|wrote the first draft|all contributed to the preparation of the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5561555	28818039	AK	2	designed the study|performed the bioinformatics data analyses|performed the cell culture work and qrt-pcr experiments|wrote the first draft|all contributed to the preparation of the manuscript	performed the bioinformatics data analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5561555	28818039	AK	2	designed the study|performed the bioinformatics data analyses|performed the cell culture work and qrt-pcr experiments|wrote the first draft|all contributed to the preparation of the manuscript	performed the cell culture work and qrt-pcr experiments	Performed the experiments	Investigation	YES
5561555	28818039	AK	2	designed the study|performed the bioinformatics data analyses|performed the cell culture work and qrt-pcr experiments|wrote the first draft|all contributed to the preparation of the manuscript	wrote the first draft	Wrote the paper	Writing - Original Draft	YES
5561555	28818039	AK	2	designed the study|performed the bioinformatics data analyses|performed the cell culture work and qrt-pcr experiments|wrote the first draft|all contributed to the preparation of the manuscript	all contributed to the preparation of the manuscript	Wrote the paper	Writing - Original Draft	YES
5561555	28818039	AP	2	performed the cell culture work and qrt-pcr experiments	performed the cell culture work and qrt-pcr experiments	Performed the experiments	Investigation	YES
5561555	28818039	CAH	2	designed the study|guided the analysis and supervised the work|all contributed to the preparation of the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5561555	28818039	CAH	2	designed the study|guided the analysis and supervised the work|all contributed to the preparation of the manuscript	guided the analysis and supervised the work	-	Supervision	YES
5561555	28818039	CAH	2	designed the study|guided the analysis and supervised the work|all contributed to the preparation of the manuscript	all contributed to the preparation of the manuscript	Wrote the paper	Writing - Original Draft	YES
5561555	28818039	MK	2	designed the study|performed the bioinformatics data analyses|guided the analysis and supervised the work|all contributed to the preparation of the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5561555	28818039	MK	2	designed the study|performed the bioinformatics data analyses|guided the analysis and supervised the work|all contributed to the preparation of the manuscript	performed the bioinformatics data analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5561555	28818039	MK	2	designed the study|performed the bioinformatics data analyses|guided the analysis and supervised the work|all contributed to the preparation of the manuscript	guided the analysis and supervised the work	-	Supervision	YES
5561555	28818039	MK	2	designed the study|performed the bioinformatics data analyses|guided the analysis and supervised the work|all contributed to the preparation of the manuscript	all contributed to the preparation of the manuscript	Wrote the paper	Writing - Original Draft	YES
5561555	28818039	OK	2	all contributed to the preparation of the manuscript	all contributed to the preparation of the manuscript	Wrote the paper	Writing - Original Draft	YES
5561555	28818039	PM	2	all contributed to the preparation of the manuscript	all contributed to the preparation of the manuscript	Wrote the paper	Writing - Original Draft	YES
4480272	26112315	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4480272	26112315	BS	2	solved crystal structures	solved crystal structures	-	-	NO
4480272	26112315	HJ	2	performed and analyzed mic and cytotoxicity experiments	performed and analyzed mic and cytotoxicity experiments	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4480272	26112315	JC	2	performed and analyzed mic and cytotoxicity experiments	performed and analyzed mic and cytotoxicity experiments	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4480272	26112315	JD	2	performed and analyzed mic and cytotoxicity experiments	performed and analyzed mic and cytotoxicity experiments	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4480272	26112315	JY	2	crystallized compounds|participated in study design	crystallized compounds	Performed the experiments	Investigation	YES
4480272	26112315	JY	2	crystallized compounds|participated in study design	participated in study design	Conceived and designed the experiments	Methodology	YES
4480272	26112315	KM	2	conceived project, produced and purified compounds, drafted manuscript	conceived project, produced and purified compounds, drafted manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
4480272	26112315	MJ	2	participated in study design	participated in study design	Conceived and designed the experiments	Methodology	YES
4480272	26112315	RS	2	gave final approval for publishing manuscript	gave final approval for publishing manuscript	-	-	NO
4480272	26112315	SM	2	participated in data analysis and drafting of the manuscript	participated in data analysis and drafting of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4412709	25919588	AO	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412709	25919588	AO	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4412709	25919588	BT	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412709	25919588	CYH	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4412709	25919588	JDC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412709	25919588	JDC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4412709	25919588	JDC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4412709	25919588	JTH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412709	25919588	JTH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412709	25919588	JTH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412709	25919588	LH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4412709	25919588	OKD	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412709	25919588	PDC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412709	25919588	PDC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412709	25919588	PDC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412709	25919588	SB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412709	25919588	SB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4412709	25919588	SB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4412709	25919588	SP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412709	25919588	SP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4412709	25919588	SP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4412709	25919588	TMT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412709	25919588	TMT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4412709	25919588	TMT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
3334681	22420682	CJW	2	planned the study, assisted with data collection and wrote the bulk of the manuscript	planned the study, assisted with data collection and wrote the bulk of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
3334681	22420682	DJB	2	helped with study design and data collection	helped with study design and data collection	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3334681	22420682	MH	2	performed genotyping and manuscript preparation	performed genotyping and manuscript preparation	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3334681	22420682	MJS	2	helped with study design, data interpretation and manuscript preparation	helped with study design, data interpretation and manuscript preparation	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3334681	22420682	MKB	2	helped with study design, performed genotyping and manuscript preparation	helped with study design, performed genotyping and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
3334681	22420682	MM	2	helped with data collection and manuscript preparation	helped with data collection and manuscript preparation	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3334681	22420682	NDL	2	assisted with data collection, study design and manuscript preparation	assisted with data collection, study design and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
3334681	22420682	WD	2	performed genotyping and manuscript preparation	performed genotyping and manuscript preparation	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6463441	30950414	BRM	1	Writing the manuscript	Writing the manuscript	Wrote the paper	Writing - Original Draft	YES
6463441	30950414	WD	1	Writing the manuscript	Writing the manuscript	Wrote the paper	Writing - Original Draft	YES
1867858	17520029	AN	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1867858	17520029	AN	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1867858	17520029	TL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5567589	28831764	AD	2	contributed to the study design and manuscript drafting	contributed to the study design and manuscript drafting	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5567589	28831764	BB	2	contributed to the data collection and manuscript drafting	contributed to the data collection and manuscript drafting	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5567589	28831764	BN	2	contributed to the contribution of imaging tool and manuscript drafting	contributed to the contribution of imaging tool and manuscript drafting	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Visualization|Writing - Original Draft	YES
5567589	28831764	CR	2	contributed to the study design, manuscript design and manuscript drafting	contributed to the study design, manuscript design and manuscript drafting	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5567589	28831764	ED	2	contributed to the data collection, manuscript drafting and manuscript language editing	contributed to the data collection, manuscript drafting and manuscript language editing	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5567589	28831764	EK	2	contributed to the study design, development of methods, data collection, data analysis and manuscript drafting	contributed to the study design, development of methods, data collection, data analysis and manuscript drafting	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
5567589	28831764	HE	2	contributed to the study design, data analysis and manuscript drafting	contributed to the study design, data analysis and manuscript drafting	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Original Draft	YES
5567589	28831764	KS	2	contributed to the data collection and manuscript drafting	contributed to the data collection and manuscript drafting	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5567589	28831764	LT	2	contributed to the study design and manuscript drafting	contributed to the study design and manuscript drafting	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5567589	28831764	MS	2	contributed to the contribution of imaging tool and manuscript drafting	contributed to the contribution of imaging tool and manuscript drafting	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Visualization|Writing - Original Draft	YES
5567589	28831764	NA	2	contributed to the development of methods, data collection and manuscript drafting	contributed to the development of methods, data collection and manuscript drafting	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Methodology|Resources|Writing - Original Draft	YES
1867859	17520012	CG	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1867859	17520012	CG	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1867859	17520012	HI	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1867859	17520012	HI	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1867859	17520012	LK	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1867859	17520012	LK	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1867859	17520012	LM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1867859	17520012	OR	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1867859	17520012	SM	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1867859	17520012	SM	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4412710	25919309	KSP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412710	25919309	KSP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412710	25919309	KSP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412710	25919309	KSP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412710	25919309	NWG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412710	25919309	NWG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412710	25919309	NWG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412710	25919309	NWG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412710	25919309	SSB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412710	25919309	SSB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412710	25919309	SSB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3342894	22480293	AHLJ	2	have participated in data interpretation and manuscript review	have participated in data interpretation and manuscript review	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
3342894	22480293	BG	2	was a significant writer and responsible for data interpretation	was a significant writer and responsible for data interpretation	Analyzed the data|Wrote the paper	Formal analysis	YES
3342894	22480293	CRRA	2	was a significant writer and responsible for concept and design, experimental procedures, data analyses and interpretation	was a significant writer and responsible for concept and design, experimental procedures, data analyses and interpretation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology	YES
3342894	22480293	HN	2	have participated in experimental procedures, data interpretation and manuscript preparation	have participated in experimental procedures, data interpretation and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3342894	22480293	IHM	2	have participated in experimental procedures, data interpretation and manuscript preparation	have participated in experimental procedures, data interpretation and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3342894	22480293	LRGB	2	have participated in experimental procedures, data interpretation and manuscript preparation	have participated in experimental procedures, data interpretation and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3342894	22480293	MCI	2	have participated in data interpretation and manuscript review	have participated in data interpretation and manuscript review	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
3342894	22480293	PCB	2	have participated in data interpretation and manuscript review	have participated in data interpretation and manuscript review	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
3342894	22480293	PR	2	have participated in experimental procedures, data interpretation and manuscript preparation	have participated in experimental procedures, data interpretation and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4489976	26137911	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4489976	26137911	JB	2	synthesized the small oxidative molecules, contributed substantially for the conception of this work and also critically revising the paper	synthesized the small oxidative molecules, contributed substantially for the conception of this work and also critically revising the paper	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Review & Editing	YES
4489976	26137911	LSFC	2	contributed to experiments planning, carried out the molecular genetic experiments to generate two of the recombinant strains, carried out the small oxidative molecules supplement experiments, obtained the data, and worked on the paper draft	contributed to experiments planning, carried out the molecular genetic experiments to generate two of the recombinant strains, carried out the small oxidative molecules supplement experiments, obtained the data, and worked on the paper draft	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Methodology|Resources|Writing - Original Draft	YES
4489976	26137911	MB	2	contributed to the design of the work, revised it critically and contributing to intellectual content	contributed to the design of the work, revised it critically and contributing to intellectual content	Conceived and designed the experiments|Wrote the paper	Writing - Review & Editing	YES
4489976	26137911	MT	2	participated on the experiments planning and conception, carried out molecular genetic experiments to obtain one of the recombinant strains and critically revised the paper for important intellectual content	participated on the experiments planning and conception, carried out molecular genetic experiments to obtain one of the recombinant strains and critically revised the paper for important intellectual content	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Writing - Review & Editing	YES
4489976	26137911	Miller Tran	2	have equity in triton health and nutrition, which could be impacted by this research	have equity in triton health and nutrition, which could be impacted by this research	-	-	NO
4489976	26137911	SPM	2	contributed to conception and work design, data interpretation and critical revision	contributed to conception and work design, data interpretation and critical revision	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Resources|Writing - Review & Editing	YES
4489976	26137911	Stephen P. Mayfield	2	have equity in triton health and nutrition, which could be impacted by this research	have equity in triton health and nutrition, which could be impacted by this research	-	-	NO
4489976	26137911	The authors	2	have equity in triton health and nutrition, which could be impacted by this research	have equity in triton health and nutrition, which could be impacted by this research	-	-	NO
5574826	28853060	All authors	2	participated equally in the design of the study	participated equally in the design of the study	Conceived and designed the experiments	Methodology	YES
5574826	28853060	GEV	2	included patients	included patients	-	-	NO
5574826	28853060	KBF	2	included patients|analysed the images and performed statistical analysis|drafted the manuscript	included patients	-	-	NO
5574826	28853060	KBF	2	included patients|analysed the images and performed statistical analysis|drafted the manuscript	analysed the images and performed statistical analysis	Analyzed the data	Formal analysis|Visualization	YES
5574826	28853060	KBF	2	included patients|analysed the images and performed statistical analysis|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5574826	28853060	MS	2	analysed the images and performed statistical analysis|drafted the manuscript	analysed the images and performed statistical analysis	Analyzed the data	Formal analysis|Visualization	YES
5574826	28853060	MS	2	analysed the images and performed statistical analysis|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5574826	28853060	OLM	2	analysed the images and performed statistical analysis	analysed the images and performed statistical analysis	Analyzed the data	Formal analysis|Visualization	YES
5574826	28853060	PLE	2	analysed the images and performed statistical analysis	analysed the images and performed statistical analysis	Analyzed the data	Formal analysis|Visualization	YES
5574826	28853060	SK	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4600551	26491692	Ahmad Nassar	2	contributed equally to this work	contributed equally to this work	-	-	NO
4600551	26491692	Matthew Boyko	2	contributed equally to this work	contributed equally to this work	-	-	NO
5702019	29209344	All the authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5702019	29209344	CW	2	conceived and designed the study|performed the laboratory work|analyzed the data and wrote the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5702019	29209344	CW	2	conceived and designed the study|performed the laboratory work|analyzed the data and wrote the manuscript	performed the laboratory work	Performed the experiments	Investigation	YES
5702019	29209344	CW	2	conceived and designed the study|performed the laboratory work|analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5702019	29209344	MU	2	conceived and designed the study|analyzed the data and wrote the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5702019	29209344	MU	2	conceived and designed the study|analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5702019	29209344	PR	2	conceived and designed the study|analyzed the data and wrote the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5702019	29209344	PR	2	conceived and designed the study|analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5702019	29209344	TD	2	performed the laboratory work	performed the laboratory work	Performed the experiments	Investigation	YES
6463442	30950418	NM	4	Author contributions Conception and literature search: were conducted by	Author contributions Conception and literature search: were conducted by	Conceived and designed the experiments|Performed the experiments	Conceptualization|Formal analysis|Investigation	YES
6463442	30950418	TCH	4	Author contributions Conception and literature search: were conducted by	Author contributions Conception and literature search: were conducted by	Conceived and designed the experiments|Performed the experiments	Conceptualization|Formal analysis|Investigation	YES
1867860	17520025	AF	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1867860	17520025	AF	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1867860	17520025	DD	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1867860	17520025	DD	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1867860	17520025	KK	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1867860	17520025	LW	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1867860	17520025	LW	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1867860	17520025	SK	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1867860	17520025	SK	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1867860	17520025	SL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1867860	17520025	SP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1867860	17520025	TD	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1867860	17520025	WT	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
3349497	22490509	All authors	2	approved the final version to be published	approved the final version to be published	-	-	NO
3349497	22490509	BRR	2	contributed to conception and design, analysis and interpretation of data	contributed to conception and design, analysis and interpretation of data	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Resources	YES
3349497	22490509	GV	2	contributed to conception and design, analysis and interpretation of data	contributed to conception and design, analysis and interpretation of data	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Resources	YES
3349497	22490509	SE	2	contributed to conception and design, analysis and interpretation of data|drafted the paper and all authors contributed by revising it critically	contributed to conception and design, analysis and interpretation of data	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Resources	YES
3349497	22490509	SE	2	contributed to conception and design, analysis and interpretation of data|drafted the paper and all authors contributed by revising it critically	drafted the paper and all authors contributed by revising it critically	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
1868595	17520027	TT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1868595	17520027	TT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1868595	17520027	TT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1868595	17520027	YS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1868595	17520027	YS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1868595	17520027	YS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412711	25919357	LB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412711	25919357	LB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412711	25919357	LB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412711	25919357	LB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412711	25919357	MM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412711	25919357	MM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412711	25919357	MM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412711	25919357	TB	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412711	25919357	VP	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4412711	25919357	VP	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5561584	28818038	All of the authors	PLoS52	contributed to the writing of the manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5561584	28818038	BD	PLoS52	conceived and designed the experiments|interpreted the results	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5561584	28818038	BD	PLoS52	conceived and designed the experiments|interpreted the results	interpreted the results	Analyzed the data	Formal analysis	YES
5561584	28818038	CP	PLoS52	conceived and designed the experiments|performed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5561584	28818038	CP	PLoS52	conceived and designed the experiments|performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5561584	28818038	FR	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5561584	28818038	JFP	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5561584	28818038	JFP	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5561584	28818038	THMS	PLoS52	conceived and designed the experiments|interpreted the results	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5561584	28818038	THMS	PLoS52	conceived and designed the experiments|interpreted the results	interpreted the results	Analyzed the data	Formal analysis	YES
5561584	28818038	TK	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|interpreted the results	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5561584	28818038	TK	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|interpreted the results	performed the experiments	Performed the experiments	Investigation	YES
5561584	28818038	TK	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|interpreted the results	analyzed the data	Analyzed the data	Formal analysis	YES
5561584	28818038	TK	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|interpreted the results	interpreted the results	Analyzed the data	Formal analysis	YES
5702293	29209354	AS	PLoS52	performed the metabolism experiment	performed the metabolism experiment	Performed the experiments	Investigation	YES
5702293	29209354	DV	PLoS52	conceived and designed the experiments|performed the metabolism experiment|interpreted the results and wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5702293	29209354	DV	PLoS52	conceived and designed the experiments|performed the metabolism experiment|interpreted the results and wrote the manuscript	performed the metabolism experiment	Performed the experiments	Investigation	YES
5702293	29209354	DV	PLoS52	conceived and designed the experiments|performed the metabolism experiment|interpreted the results and wrote the manuscript	interpreted the results and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5702293	29209354	EK	PLoS52	conceived and designed the experiments|performed the metabolism experiment|performed the development experiment|interpreted the results and wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5702293	29209354	EK	PLoS52	conceived and designed the experiments|performed the metabolism experiment|performed the development experiment|interpreted the results and wrote the manuscript	performed the metabolism experiment	Performed the experiments	Investigation	YES
5702293	29209354	EK	PLoS52	conceived and designed the experiments|performed the metabolism experiment|performed the development experiment|interpreted the results and wrote the manuscript	performed the development experiment	Performed the experiments	Investigation	YES
5702293	29209354	EK	PLoS52	conceived and designed the experiments|performed the metabolism experiment|performed the development experiment|interpreted the results and wrote the manuscript	interpreted the results and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5702293	29209354	JG	PLoS52	conceived and designed the experiments|interpreted the results and wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5702293	29209354	JG	PLoS52	conceived and designed the experiments|interpreted the results and wrote the manuscript	interpreted the results and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5702293	29209354	KS	PLoS52	performed the metabolism experiment	performed the metabolism experiment	Performed the experiments	Investigation	YES
5702293	29209354	VJ	PLoS52	conceived and designed the experiments|performed the development experiment|interpreted the results and wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5702293	29209354	VJ	PLoS52	conceived and designed the experiments|performed the development experiment|interpreted the results and wrote the manuscript	performed the development experiment	Performed the experiments	Investigation	YES
5702293	29209354	VJ	PLoS52	conceived and designed the experiments|performed the development experiment|interpreted the results and wrote the manuscript	interpreted the results and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3353850	22471891	JLP	2	participated in drafting, editing, and submitting the manuscript	participated in drafting, editing, and submitting the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3353850	22471891	SASC	2	assisted with study design, statistical analysis and critically reviewed the manuscript for intellectual content	assisted with study design, statistical analysis and critically reviewed the manuscript for intellectual content	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
3353850	22471891	TS	2	supervised the research group, ran the statistical analysis, interpreted data, and was involved with manuscript drafting	supervised the research group, ran the statistical analysis, interpreted data, and was involved with manuscript drafting	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Supervision|Writing - Original Draft	YES
1868596	17534423	AP	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1868596	17534423	AP	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1868596	17534423	CB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1868596	17534423	CL	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1868596	17534423	CL	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1868596	17534423	DP	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1868596	17534423	DP	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1868596	17534423	ET	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1868596	17534423	MD	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1868596	17534423	NT	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1868596	17534423	RB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1868596	17534423	RC	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1868596	17534423	RN	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5574834	28853043	All authors	2	drafted and edited the article and approved the final manuscript	drafted and edited the article and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5574834	28853043	HD	2	carried out the data analysis and interpretation	carried out the data analysis and interpretation	Analyzed the data	Formal analysis	YES
5574834	28853043	TN	2	conceived of and made the study design|carried out the data analysis and interpretation|carried out the data analysis and interpretation|participated in the collection and assembly of the data	conceived of and made the study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5574834	28853043	TN	2	conceived of and made the study design|carried out the data analysis and interpretation|carried out the data analysis and interpretation|participated in the collection and assembly of the data	carried out the data analysis and interpretation	Analyzed the data	Formal analysis	YES
5574834	28853043	TN	2	conceived of and made the study design|carried out the data analysis and interpretation|carried out the data analysis and interpretation|participated in the collection and assembly of the data	carried out the data analysis and interpretation	Analyzed the data	Formal analysis	YES
5574834	28853043	TN	2	conceived of and made the study design|carried out the data analysis and interpretation|carried out the data analysis and interpretation|participated in the collection and assembly of the data	participated in the collection and assembly of the data	Performed the experiments	Investigation	YES
5574834	28853043	YM	2	carried out the data analysis and interpretation	carried out the data analysis and interpretation	Analyzed the data	Formal analysis	YES
5574834	28853043	YN	2	conceived of and made the study design|participated in the collection and assembly of the data	conceived of and made the study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5574834	28853043	YN	2	conceived of and made the study design|participated in the collection and assembly of the data	participated in the collection and assembly of the data	Performed the experiments	Investigation	YES
5574834	28853043	YY	2	conceived of and made the study design|participated in the collection and assembly of the data	conceived of and made the study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5574834	28853043	YY	2	conceived of and made the study design|participated in the collection and assembly of the data	participated in the collection and assembly of the data	Performed the experiments	Investigation	YES
4600553	26491680	Andreas Kolk	2	contributed equally to this work	contributed equally to this work	-	-	NO
4600553	26491680	Robert Kohnke	2	contributed equally to this work	contributed equally to this work	-	-	NO
4492345	26141525	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5561633	28818044	BFK	5	performed rna and cdna preparations	performed rna and cdna preparations	Performed the experiments	Investigation	YES
5561633	28818044	BJGS	5	performed qpcr laboratory work and analysis	performed qpcr laboratory work and analysis	Performed the experiments	Investigation	YES
5561633	28818044	JDP	5	wrote the manuscript with JDP	wrote the manuscript with JDP	Wrote the paper	Writing - Original Draft	YES
5561633	28818044	SRMJ	5	performed rna and cdna preparations	performed rna and cdna preparations	Performed the experiments	Investigation	YES
4412713	25919455	EGH	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412713	25919455	EGH	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412713	25919455	LVDM	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412713	25919455	LVDM	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412713	25919455	MD	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412713	25919455	MD	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412713	25919455	MD	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412713	25919455	MM	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412713	25919455	PDVH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412713	25919455	PDVH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5702303	29209353	All authors	2	reviewed and contributed to draft the manuscript as well as read and approved the final manuscript	reviewed and contributed to draft the manuscript as well as read and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5702303	29209353	CQ	2	carried out the ifc genotyping	carried out the ifc genotyping	Performed the experiments	Investigation	YES
5702303	29209353	GG-S	2	provided the genotyping infrastructure	provided the genotyping infrastructure	Performed the experiments	Investigation	YES
5702303	29209353	JB-C	2	carried out the ifc genotyping	carried out the ifc genotyping	Performed the experiments	Investigation	YES
5702303	29209353	JO-G	2	conceptualized and conceived the project and its components|carried out the ifc genotyping	conceptualized and conceived the project and its components	Conceived and designed the experiments	Conceptualization	YES
5702303	29209353	JO-G	2	conceptualized and conceived the project and its components|carried out the ifc genotyping	carried out the ifc genotyping	Performed the experiments	Investigation	YES
5702303	29209353	RC	2	conducted the phenotypic evaluation	conducted the phenotypic evaluation	Performed the experiments	Investigation	YES
5702303	29209353	RY	2	conceptualized and conceived the project and its components|corrected and edited it	conceptualized and conceived the project and its components	Conceived and designed the experiments	Conceptualization	YES
5702303	29209353	RY	2	conceptualized and conceived the project and its components|corrected and edited it	corrected and edited it	Wrote the paper	Writing - Review & Editing	YES
5702303	29209353	YZ	2	carried out the ifc genotyping	carried out the ifc genotyping	Performed the experiments	Investigation	YES
3356228	22512917	BHA	2	assisted in funding, providing resources, and manuscript preparation	assisted in funding, providing resources, and manuscript preparation	Contributed reagents/materials/analysis tools|Wrote the paper	Funding acquisition|Resources|Writing - Original Draft	YES
3356228	22512917	IM	2	assisted in study design, data collection and conducted the myofiber dimension analysis	assisted in study design, data collection and conducted the myofiber dimension analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
3356228	22512917	JMW	2	was responsible for study design, data collection, molecular and gene analysis, and manuscript preparation	was responsible for study design, data collection, molecular and gene analysis, and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
3356228	22512917	JPL	2	helped extensively in manuscript preparation	helped extensively in manuscript preparation	Wrote the paper	Writing - Original Draft	YES
3356228	22512917	JRS	2	helped extensively in manuscript preparation	helped extensively in manuscript preparation	Wrote the paper	Writing - Original Draft	YES
3356228	22512917	LBP	2	assisted in funding, providing resources, and manuscript preparation	assisted in funding, providing resources, and manuscript preparation	Contributed reagents/materials/analysis tools|Wrote the paper	Funding acquisition|Resources|Writing - Original Draft	YES
3356228	22512917	PCH	2	assisted in data collection/analysis for the study, and harvesting of tissues	assisted in data collection/analysis for the study, and harvesting of tissues	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3356228	22512917	PI	2	for the present study responsible for funding, providing resources, study design, supervising data collection and tissue analysis, and manuscript preparation	for the present study responsible for funding, providing resources, study design, supervising data collection and tissue analysis, and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Funding acquisition|Investigation|Methodology|Resources|Supervision|Writing - Original Draft	YES
3356228	22512917	S-rL	2	assisted in data collection/analysis for the study, and harvesting of tissues	assisted in data collection/analysis for the study, and harvesting of tissues	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3356228	22512917	SCG	2	assisted in study design, data collection and conducted the myofiber dimension analysis	assisted in study design, data collection and conducted the myofiber dimension analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
3356228	22512917	Y-mP	2	assisted in data collection/analysis for the study, and harvesting of tissues	assisted in data collection/analysis for the study, and harvesting of tissues	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5578947	28861740	HLK	2	contributed to the study design, and manuscript editing and review	contributed to the study design, and manuscript editing and review	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5578947	28861740	HNK	2	is the guarantor of integrity of the entire study, is responsible for the data analysis, statistical analysis, and manuscript writing	is the guarantor of integrity of the entire study, is responsible for the data analysis, statistical analysis, and manuscript writing	Analyzed the data|Wrote the paper	Data curation|Formal analysis|Writing - Original Draft	YES
5578947	28861740	HS	2	contributed to the study design, and manuscript editing and review	contributed to the study design, and manuscript editing and review	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5578947	28861740	JYK	2	is the guarantor of integrity of the entire study, is responsible for the data analysis, statistical analysis, and manuscript writing	is the guarantor of integrity of the entire study, is responsible for the data analysis, statistical analysis, and manuscript writing	Analyzed the data|Wrote the paper	Data curation|Formal analysis|Writing - Original Draft	YES
5578947	28861740	SR	2	helped in the data collection and data analysis	helped in the data collection and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5578947	28861740	YC	2	helped in the data collection and data analysis	helped in the data collection and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5578947	28861740	YY	2	helped in the data analysis	helped in the data analysis	Analyzed the data	Formal analysis	YES
1868597	17534421	AR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1868597	17534421	AR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1868597	17534421	AR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1868597	17534421	GA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1868597	17534421	GA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1868597	17534421	GA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1868597	17534421	GA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1868597	17534421	JM	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1868597	17534421	JP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1868597	17534421	MG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1868597	17534421	SP	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1868597	17534421	SP	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5562975	28821223	BM	2	contributed to the design of the experiment|implemented the experiment and sample collection	contributed to the design of the experiment	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5562975	28821223	BM	2	contributed to the design of the experiment|implemented the experiment and sample collection	implemented the experiment and sample collection	Performed the experiments	Investigation	YES
5562975	28821223	CF	2	contributed to the design of the experiment|implemented the experiment and sample collection|conducted the molecular analysis|analyzed and interpreted the results|prepared the manuscript, and all authors read and approved of final manuscript	contributed to the design of the experiment	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5562975	28821223	CF	2	contributed to the design of the experiment|implemented the experiment and sample collection|conducted the molecular analysis|analyzed and interpreted the results|prepared the manuscript, and all authors read and approved of final manuscript	implemented the experiment and sample collection	Performed the experiments	Investigation	YES
5562975	28821223	CF	2	contributed to the design of the experiment|implemented the experiment and sample collection|conducted the molecular analysis|analyzed and interpreted the results|prepared the manuscript, and all authors read and approved of final manuscript	conducted the molecular analysis	Performed the experiments	Investigation	YES
5562975	28821223	CF	2	contributed to the design of the experiment|implemented the experiment and sample collection|conducted the molecular analysis|analyzed and interpreted the results|prepared the manuscript, and all authors read and approved of final manuscript	analyzed and interpreted the results	Analyzed the data	Formal analysis	YES
5562975	28821223	CF	2	contributed to the design of the experiment|implemented the experiment and sample collection|conducted the molecular analysis|analyzed and interpreted the results|prepared the manuscript, and all authors read and approved of final manuscript	prepared the manuscript, and all authors read and approved of final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5562975	28821223	FP	2	contributed to the design of the experiment|conducted the molecular analysis|analyzed and interpreted the results|prepared the manuscript, and all authors read and approved of final manuscript	contributed to the design of the experiment	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5562975	28821223	FP	2	contributed to the design of the experiment|conducted the molecular analysis|analyzed and interpreted the results|prepared the manuscript, and all authors read and approved of final manuscript	conducted the molecular analysis	Performed the experiments	Investigation	YES
5562975	28821223	FP	2	contributed to the design of the experiment|conducted the molecular analysis|analyzed and interpreted the results|prepared the manuscript, and all authors read and approved of final manuscript	analyzed and interpreted the results	Analyzed the data	Formal analysis	YES
5562975	28821223	FP	2	contributed to the design of the experiment|conducted the molecular analysis|analyzed and interpreted the results|prepared the manuscript, and all authors read and approved of final manuscript	prepared the manuscript, and all authors read and approved of final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5562975	28821223	KS	2	contributed to the design of the experiment|implemented the experiment and sample collection	contributed to the design of the experiment	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5562975	28821223	KS	2	contributed to the design of the experiment|implemented the experiment and sample collection	implemented the experiment and sample collection	Performed the experiments	Investigation	YES
5562975	28821223	KW	2	contributed to the design of the experiment|implemented the experiment and sample collection|analyzed and interpreted the results|prepared the manuscript, and all authors read and approved of final manuscript	contributed to the design of the experiment	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5562975	28821223	KW	2	contributed to the design of the experiment|implemented the experiment and sample collection|analyzed and interpreted the results|prepared the manuscript, and all authors read and approved of final manuscript	implemented the experiment and sample collection	Performed the experiments	Investigation	YES
5562975	28821223	KW	2	contributed to the design of the experiment|implemented the experiment and sample collection|analyzed and interpreted the results|prepared the manuscript, and all authors read and approved of final manuscript	analyzed and interpreted the results	Analyzed the data	Formal analysis	YES
5562975	28821223	KW	2	contributed to the design of the experiment|implemented the experiment and sample collection|analyzed and interpreted the results|prepared the manuscript, and all authors read and approved of final manuscript	prepared the manuscript, and all authors read and approved of final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5562975	28821223	SP	2	contributed to the design of the experiment	contributed to the design of the experiment	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6463446	30950417	The author	2	completed the manuscript independently	completed the manuscript independently	-	-	NO
6463447	30950415	HMRK	1	Design of the study	Design of the study	Conceived and designed the experiments	Methodology	YES
6463447	30950415	MK	1	Design of the study	Design of the study	Conceived and designed the experiments	Methodology	YES
6463447	30950415	MS	1	Design of the study	Design of the study	Conceived and designed the experiments	Methodology	YES
4600555	26491682	Fabian Duttenhoefer	2	contributed equally to this work	contributed equally to this work	-	-	NO
4600555	26491682	Rafael Lara	2	contributed equally to this work	contributed equally to this work	-	-	NO
3356240	22400992	All authors	2	were involved in the study	were involved in the study	-	-	NO
3356240	22400992	JDR	2	was principal researcher, involved with liason with the company, participant screening, beverage assignment, data collection, statistical analysis and report generation	was principal researcher, involved with liason with the company, participant screening, beverage assignment, data collection, statistical analysis and report generation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3356240	22400992	LSK	2	was involved with monitoring of data collection including collation of performance data, and test beverage administration, as well as overview and editing of manuscript	was involved with monitoring of data collection including collation of performance data, and test beverage administration, as well as overview and editing of manuscript	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Review & Editing	YES
3356240	22400992	MDT	2	was co-researcher involved with cohort organization, data collection and blood analyses, confirmation of statistical analyses, and helped to draft the manuscript	was co-researcher involved with cohort organization, data collection and blood analyses, confirmation of statistical analyses, and helped to draft the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3356240	22400992	MGR	2	was involved in quality control, part data collection, and technical accuracy in preparation of the manuscript	was involved in quality control, part data collection, and technical accuracy in preparation of the manuscript	Performed the experiments|Wrote the paper	Investigation|Validation|Writing - Original Draft	YES
4412715	25919494	AH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412715	25919494	AH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412715	25919494	AH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412715	25919494	AH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412715	25919494	HHA	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412715	25919494	HHA	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412715	25919494	JE	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412715	25919494	JMD	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412715	25919494	WJ	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4412715	25919494	WJ	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4520822	26228353	AFA	2	participated in the design of primers, interpretation of data and helped to draft the manuscript	participated in the design of primers, interpretation of data and helped to draft the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4520822	26228353	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4520822	26228353	HMA	2	participated in its design and coordination, interpretation of data, and helped to draft the manuscript	participated in its design and coordination, interpretation of data, and helped to draft the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Project administration|Writing - Original Draft	YES
4520822	26228353	MPL	2	carried out the experimental studies, participated in the sequence analyses and alignments, in the design of the study and drafted the manuscript	carried out the experimental studies, participated in the sequence analyses and alignments, in the design of the study and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
1868598	17534424	DH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1868598	17534424	JE	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1868598	17534424	JE	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1868598	17534424	JE	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1868598	17534424	JS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1868598	17534424	SI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1868598	17534424	SI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1868598	17534424	SI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1868598	17534424	SI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1868598	17534424	WA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1868598	17534424	WA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1868598	17534424	WA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5587506	28879508	JMN	2	designed the study|worked together on statistical analysis and data interpretation|oversaw the study	designed the study	Conceived and designed the experiments	Methodology	YES
5587506	28879508	JMN	2	designed the study|worked together on statistical analysis and data interpretation|oversaw the study	worked together on statistical analysis and data interpretation	Performed the experiments|Analyzed the data	Formal analysis	YES
5587506	28879508	JMN	2	designed the study|worked together on statistical analysis and data interpretation|oversaw the study	oversaw the study	-	Supervision	YES
5587506	28879508	NG	2	designed the study|collected, anonymized and analysed all data sets|worked together on statistical analysis and data interpretation|led the write up of the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5587506	28879508	NG	2	designed the study|collected, anonymized and analysed all data sets|worked together on statistical analysis and data interpretation|led the write up of the manuscript	collected, anonymized and analysed all data sets	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5587506	28879508	NG	2	designed the study|collected, anonymized and analysed all data sets|worked together on statistical analysis and data interpretation|led the write up of the manuscript	worked together on statistical analysis and data interpretation	Performed the experiments|Analyzed the data	Formal analysis	YES
5587506	28879508	NG	2	designed the study|collected, anonymized and analysed all data sets|worked together on statistical analysis and data interpretation|led the write up of the manuscript	led the write up of the manuscript	Wrote the paper	Writing - Original Draft	YES
5587506	28879508	PET-CT	2	acquisition and analysis	acquisition and analysis	-	-	NO
5587506	28879508	PK	2	designed the study|oversaw the study	designed the study	Conceived and designed the experiments	Methodology	YES
5587506	28879508	PK	2	designed the study|oversaw the study	oversaw the study	-	Supervision	YES
5587506	28879508	SF	2	designed the study|worked together on statistical analysis and data interpretation	designed the study	Conceived and designed the experiments	Methodology	YES
5587506	28879508	SF	2	designed the study|worked together on statistical analysis and data interpretation	worked together on statistical analysis and data interpretation	Performed the experiments|Analyzed the data	Formal analysis	YES
5587506	28879508	all authors	2	contributed to revising the manuscript and all approved the final manuscript	contributed to revising the manuscript and all approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5702310	29209352	LJ	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
5702310	29209352	MR	PLoS52	designed the research|analyzed data|wrote the paper	designed the research	Conceived and designed the experiments	Methodology	YES
5702310	29209352	MR	PLoS52	designed the research|analyzed data|wrote the paper	analyzed data	Analyzed the data	Formal analysis	YES
5702310	29209352	MR	PLoS52	designed the research|analyzed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5702310	29209352	RD	PLoS52	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5702310	29209352	RR	PLoS52	analyzed data|wrote the paper	analyzed data	Analyzed the data	Formal analysis	YES
5702310	29209352	RR	PLoS52	analyzed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5702310	29209352	SF	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
5702310	29209352	SL	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
5702310	29209352	SZ	PLoS52	designed the research|performed research|analyzed data|wrote the paper	designed the research	Conceived and designed the experiments	Methodology	YES
5702310	29209352	SZ	PLoS52	designed the research|performed research|analyzed data|wrote the paper	performed research	Performed the experiments	Investigation	YES
5702310	29209352	SZ	PLoS52	designed the research|performed research|analyzed data|wrote the paper	analyzed data	Analyzed the data	Formal analysis	YES
5702310	29209352	SZ	PLoS52	designed the research|performed research|analyzed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5702310	29209352	XZ	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
5702310	29209352	YW	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
5702310	29209352	ZL	PLoS52	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
4600556	26491693	Byung-Chul Jeong	2	contributed equally to this work	contributed equally to this work	-	-	NO
4600556	26491693	Hyuck Choi	2	contributed equally to this work	contributed equally to this work	-	-	NO
5563000	28821232	AC	2	interpreted the results and improved the manuscript	interpreted the results and improved the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5563000	28821232	FC	2	interpreted the results and improved the manuscript	interpreted the results and improved the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5563000	28821232	LST	2	guided data acquisition methodology and critically revised the intellectual content of the manuscript for submission	guided data acquisition methodology and critically revised the intellectual content of the manuscript for submission	Performed the experiments|Wrote the paper	Investigation|Methodology|Supervision|Writing - Review & Editing	YES
5563000	28821232	MN	2	conducted some experiments, interpreted the results, and improved the manuscript	conducted some experiments, interpreted the results, and improved the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
5563000	28821232	MOS	2	interpreted the results and improved the manuscript	interpreted the results and improved the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5563000	28821232	RO	2	carried out the experiments, analyzed the data, interpreted the results, created the figure, and drafted of the manuscript	carried out the experiments, analyzed the data, interpreted the results, created the figure, and drafted of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Visualization|Writing - Original Draft	YES
5563000	28821232	SM	2	interpreted the results and improved the manuscript	interpreted the results and improved the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
3366912	22472466	BK	2	collected the data at the race	collected the data at the race	Performed the experiments	Investigation	YES
3366912	22472466	CAR	2	assisted in data analysis, data interpretation and manuscript preparation	assisted in data analysis, data interpretation and manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3366912	22472466	CC	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3366912	22472466	PK	2	collected the data at the race	collected the data at the race	Performed the experiments	Investigation	YES
3366912	22472466	TR	2	assisted in data analysis, data interpretation and manuscript preparation	assisted in data analysis, data interpretation and manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
1868777	17534428	AM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1868777	17534428	AM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1868777	17534428	AM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1868777	17534428	AM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1868777	17534428	DG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1868777	17534428	DG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1868777	17534428	DG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1868777	17534428	EL	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1868777	17534428	KL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1868777	17534428	MP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1868777	17534428	MP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1868777	17534428	MP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1868777	17534428	MP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1868777	17534428	MP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1868777	17534428	PC	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1868777	17534428	PC	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1868777	17534428	PC	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1868777	17534428	PD	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1868777	17534428	VA	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1868777	17534428	WZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1868777	17534428	WZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1868777	17534428	WZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1868777	17534428	WZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412716	25919001	DM	PLoS5	Collected data	Collected data	Performed the experiments	Investigation	YES
4412716	25919001	HM	PLoS5	Collected data	Collected data	Performed the experiments	Investigation	YES
4412716	25919001	JK	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412716	25919001	JK	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412716	25919001	KM	PLoS5	Revised the manuscript for content|Collected data	Revised the manuscript for content	Wrote the paper	Writing - Review & Editing	YES
4412716	25919001	KM	PLoS5	Revised the manuscript for content|Collected data	Collected data	Performed the experiments	Investigation	YES
4412716	25919001	RY	PLoS5	Wrote the paper|Collected data	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412716	25919001	RY	PLoS5	Wrote the paper|Collected data	Collected data	Performed the experiments	Investigation	YES
4412716	25919001	SS	PLoS5	Collected data	Collected data	Performed the experiments	Investigation	YES
4412716	25919001	SY	PLoS5	Collected data	Collected data	Performed the experiments	Investigation	YES
4412716	25919001	TM	PLoS5	Wrote the paper|Collected data	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412716	25919001	TM	PLoS5	Wrote the paper|Collected data	Collected data	Performed the experiments	Investigation	YES
4412716	25919001	YK	PLoS5	Analyzed the data|Wrote the paper|Collected data	Analyzed the data	Analyzed the data	Formal analysis	YES
4412716	25919001	YK	PLoS5	Analyzed the data|Wrote the paper|Collected data	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412716	25919001	YK	PLoS5	Analyzed the data|Wrote the paper|Collected data	Collected data	Performed the experiments	Investigation	YES
4412716	25919001	ZYS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Collected data	Performed the experiments	Performed the experiments	Investigation	YES
4412716	25919001	ZYS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Collected data	Analyzed the data	Analyzed the data	Formal analysis	YES
4412716	25919001	ZYS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Collected data	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412716	25919001	ZYS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Collected data	Collected data	Performed the experiments	Investigation	YES
5602811	28916904	All authors	2	participated in the study conception and design|participated in the data analysis and interpretation|participated in the revision of the manuscript and approved the final version of the manuscript	participated in the study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5602811	28916904	All authors	2	participated in the study conception and design|participated in the data analysis and interpretation|participated in the revision of the manuscript and approved the final version of the manuscript	participated in the data analysis and interpretation	Analyzed the data	Formal analysis	YES
5602811	28916904	All authors	2	participated in the study conception and design|participated in the data analysis and interpretation|participated in the revision of the manuscript and approved the final version of the manuscript	participated in the revision of the manuscript and approved the final version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5602811	28916904	BL	2	were involved in the patient recruitment	were involved in the patient recruitment	Performed the experiments	Investigation	YES
5602811	28916904	EJH	2	wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
5602811	28916904	JK	2	were involved in the patient recruitment	were involved in the patient recruitment	Performed the experiments	Investigation	YES
5602811	28916904	WHC	2	controlled the image acquisition and processing|made a critical revision	controlled the image acquisition and processing	Analyzed the data	Visualization	YES
5602811	28916904	WHC	2	controlled the image acquisition and processing|made a critical revision	made a critical revision	Wrote the paper	Writing - Review & Editing	YES
5602811	28916904	YHP	2	controlled the image acquisition and processing	controlled the image acquisition and processing	Analyzed the data	Visualization	YES
4412717	25919040	HYH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Responsible for performing database management, data analysis and statistic testing	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412717	25919040	HYH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Responsible for performing database management, data analysis and statistic testing	Performed the experiments	Performed the experiments	Investigation	YES
4412717	25919040	HYH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Responsible for performing database management, data analysis and statistic testing	Analyzed the data	Analyzed the data	Formal analysis	YES
4412717	25919040	HYH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Responsible for performing database management, data analysis and statistic testing	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412717	25919040	HYH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Responsible for performing database management, data analysis and statistic testing	Responsible for performing database management, data analysis and statistic testing	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Formal analysis|Investigation|Software	YES
4412717	25919040	SSC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Responsible for the design and implementation of the study	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412717	25919040	SSC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Responsible for the design and implementation of the study	Performed the experiments	Performed the experiments	Investigation	YES
4412717	25919040	SSC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Responsible for the design and implementation of the study	Analyzed the data	Analyzed the data	Formal analysis	YES
4412717	25919040	SSC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Responsible for the design and implementation of the study	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412717	25919040	SSC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Responsible for the design and implementation of the study	Responsible for the design and implementation of the study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3382422	22413851	ASF	2	conducted the orthopaedic examinations	conducted the orthopaedic examinations	Performed the experiments	Investigation	YES
3382422	22413851	All authors	2	contributed to the interpretation of results, critically reviewed the manuscript for intellectual content, and gave approval of the final version of the manuscript to be published	contributed to the interpretation of results, critically reviewed the manuscript for intellectual content, and gave approval of the final version of the manuscript to be published	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
3382422	22413851	DSM	2	conceived the study idea and analysed the data|designed the study|drafted the manuscript	conceived the study idea and analysed the data	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
3382422	22413851	DSM	2	conceived the study idea and analysed the data|designed the study|drafted the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
3382422	22413851	DSM	2	conceived the study idea and analysed the data|designed the study|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
3382422	22413851	RKE	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
3382422	22413851	RY	2	conceived the study idea and analysed the data|designed the study|carried out data collection|drafted the manuscript	conceived the study idea and analysed the data	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
3382422	22413851	RY	2	conceived the study idea and analysed the data|designed the study|carried out data collection|drafted the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
3382422	22413851	RY	2	conceived the study idea and analysed the data|designed the study|carried out data collection|drafted the manuscript	carried out data collection	Performed the experiments	Investigation	YES
3382422	22413851	RY	2	conceived the study idea and analysed the data|designed the study|carried out data collection|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
3382422	22413851	YA	2	designed the study|carried out data collection	designed the study	Conceived and designed the experiments	Methodology	YES
3382422	22413851	YA	2	designed the study|carried out data collection	carried out data collection	Performed the experiments	Investigation	YES
5080504	27819024	Moiz A. Ansari	2	contributed equally to this work	contributed equally to this work	-	-	NO
5080504	27819024	Rahul Pal	2	contributed equally to this work	contributed equally to this work	-	-	NO
5702320	29209341	All co-authors	2	approved the final version and agreed to be accountable for all aspects of this work	approved the final version and agreed to be accountable for all aspects of this work	-	-	NO
5702320	29209341	EF	2	led the review	led the review	-	-	NO
5702320	29209341	RS	2	made substantial contributions to the conception, development and revision of this review during the various workshops of the yamsys project|made substantial contributions for the acquisition of data for the revised version and contributed critically to the revised version	made substantial contributions to the conception, development and revision of this review during the various workshops of the yamsys project	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5702320	29209341	RS	2	made substantial contributions to the conception, development and revision of this review during the various workshops of the yamsys project|made substantial contributions for the acquisition of data for the revised version and contributed critically to the revised version	made substantial contributions for the acquisition of data for the revised version and contributed critically to the revised version	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Resources|Writing - Review & Editing	YES
1868778	17534431	JP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1868778	17534431	JP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1868778	17534431	JP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1868778	17534431	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1868778	17534431	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1868778	17534431	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1868778	17534431	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1868778	17534431	MC	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1868778	17534431	MC	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5605480	28929350	AW	2	provided critical analysis of the study design and revised the manuscript	provided critical analysis of the study design and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5605480	28929350	ES	2	revised the manuscript critically	revised the manuscript critically	Wrote the paper	Writing - Review & Editing	YES
5605480	28929350	KG	2	aided in study design, patient recruitment, and revised the manuscript	aided in study design, patient recruitment, and revised the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
5605480	28929350	PC	2	revised the manuscript critically	revised the manuscript critically	Wrote the paper	Writing - Review & Editing	YES
5605480	28929350	RZ	2	revised the manuscript critically	revised the manuscript critically	Wrote the paper	Writing - Review & Editing	YES
5605480	28929350	SB	2	revised the manuscript critically	revised the manuscript critically	Wrote the paper	Writing - Review & Editing	YES
5605480	28929350	SL	2	participated in the study design, performed primary image analysis, and prepared and edited the manuscript	participated in the study design, performed primary image analysis, and prepared and edited the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Investigation|Methodology|Visualization|Writing - Original Draft|Writing - Review & Editing	YES
5605480	28929350	TH	2	participated in the study design, performed primary image analysis, and prepared and edited the manuscript	participated in the study design, performed primary image analysis, and prepared and edited the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Investigation|Methodology|Visualization|Writing - Original Draft|Writing - Review & Editing	YES
5563008	28821222	All authors	2	reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5563008	28821222	CGF	2	collected samples from healthy controls and was involved in the direction of this work	collected samples from healthy controls and was involved in the direction of this work	Performed the experiments	Investigation	YES
5563008	28821222	LY	2	planned and directed this work, recruited healthy controls, prepared the manuscript and figures, and analyzed the data	planned and directed this work, recruited healthy controls, prepared the manuscript and figures, and analyzed the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Supervision|Visualization|Writing - Original Draft	YES
5563008	28821222	MAA	2	recruited and collected samples from study subjects, and contributed to the notions of data interpretation	recruited and collected samples from study subjects, and contributed to the notions of data interpretation	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5563008	28821222	RF	2	recruited healthy controls, isolated rna, performed bioanalyzer analysis of rna, prepared whole blood lysates, performed qpcr, analyzed the data and helped prepare the manuscript	recruited healthy controls, isolated rna, performed bioanalyzer analysis of rna, prepared whole blood lysates, performed qpcr, analyzed the data and helped prepare the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4412719	25919709	HY	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412719	25919709	JO	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412719	25919709	KI	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412719	25919709	MK	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412719	25919709	MK	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412719	25919709	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412719	25919709	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412719	25919709	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412719	25919709	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412719	25919709	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412719	25919709	YF	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412719	25919709	YF	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3395580	22569039	DNF	2	contributed to data analysis, data interpretation and manuscript editing	contributed to data analysis, data interpretation and manuscript editing	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
3395580	22569039	GH	2	as the principal investigator, contributed to conception and design of the experiment, data collection and analysis, data interpretation, manuscript draft and the editorial process	as the principal investigator, contributed to conception and design of the experiment, data collection and analysis, data interpretation, manuscript draft and the editorial process	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Data curation|Formal analysis|Funding acquisition|Investigation|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
3395580	22569039	JT	2	contributed to data analysis, data interpretation and manuscript editing	contributed to data analysis, data interpretation and manuscript editing	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
3395580	22569039	MH	2	as a post-graduate student, was responsible for conception, participant recruitment, data collection, initial data analysis, interpretation and initial drafting of the manuscript	as a post-graduate student, was responsible for conception, participant recruitment, data collection, initial data analysis, interpretation and initial drafting of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
3395580	22569039	PGB	2	contributed to data analysis, data interpretation and manuscript editing	contributed to data analysis, data interpretation and manuscript editing	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
3395580	22569039	SG	2	contributed to data interpretation, data presentation and manuscript drafting and editing	contributed to data interpretation, data presentation and manuscript drafting and editing	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
1868779	17534429	AY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1868779	17534429	AY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1868779	17534429	AY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1868779	17534429	AY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1868779	17534429	MR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1868779	17534429	MR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1868779	17534429	MR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1868779	17534429	PL	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1868779	17534429	PL	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1868779	17534429	SZ	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1868779	17534429	SZ	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5702333	29209346	All authors	2	listed have made a substantial, direct and intellectual contribution to the work, and approved it for publication	listed have made a substantial, direct and intellectual contribution to the work, and approved it for publication	-	-	NO
4523564	26239029	Both authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4523564	26239029	CRIS	2	projects 3655-4100-006-00d and 3655-21000-022-d	projects 3655-4100-006-00d and 3655-21000-022-d	-	-	NO
4523564	26239029	MAN	2	conducted the experiments|drafted the manuscript	conducted the experiments	Performed the experiments	Investigation	YES
4523564	26239029	MAN	2	conducted the experiments|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4523564	26239029	PJW	2	conceived the study|conducted the experiments|drafted the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4523564	26239029	PJW	2	conceived the study|conducted the experiments|drafted the manuscript	conducted the experiments	Performed the experiments	Investigation	YES
4523564	26239029	PJW	2	conceived the study|conducted the experiments|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4523564	26239029	USDA-ARS	2	projects 3655-4100-006-00d and 3655-21000-022-d	projects 3655-4100-006-00d and 3655-21000-022-d	-	-	NO
6009434	30009012	A.O.	2	helped with sample synthesis, performed structural characterization and data analysis, and co-edited the manuscript	helped with sample synthesis, performed structural characterization and data analysis, and co-edited the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
6009434	30009012	C.Z.	2	performed optical property measurement, performed data analysis and co-edit the manuscript	performed optical property measurement, performed data analysis and co-edit the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
6009434	30009012	CTSe	2	thin-film, performed the sem characterization, performed data analysis, and co-wrote the manuscript	thin-film, performed the sem characterization, performed data analysis, and co-wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6009434	30009012	E.K.	2	performed calculations for the electronic band structure, band gap, optical absorption coefficient, and the estimated photovoltaic conversion efficiency, performed data analysis and co-wrote the manuscript	performed calculations for the electronic band structure, band gap, optical absorption coefficient, and the estimated photovoltaic conversion efficiency, performed data analysis and co-wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6009434	30009012	G.S.	2	performed calculations for the electronic band structure, band gap, optical absorption coefficient, and the estimated photovoltaic conversion efficiency, performed data analysis and co-wrote the manuscript	performed calculations for the electronic band structure, band gap, optical absorption coefficient, and the estimated photovoltaic conversion efficiency, performed data analysis and co-wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6009434	30009012	J.G.	2	performed optical property measurement, performed data analysis and co-edit the manuscript	performed optical property measurement, performed data analysis and co-edit the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
6009434	30009012	J.T.H.	2	helped with thin-film fabrication, data analysis and co-edited the manuscript	helped with thin-film fabrication, data analysis and co-edited the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
6009434	30009012	L.Q.	2	performed calculations of phonon dispersion, and elastic constants, performed data analysis and co-edit the manuscript	performed calculations of phonon dispersion, and elastic constants, performed data analysis and co-edit the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
6009434	30009012	L.W.	2	performed calculations for the electronic band structure, band gap, optical absorption coefficient, and the estimated photovoltaic conversion efficiency, performed data analysis and co-wrote the manuscript	performed calculations for the electronic band structure, band gap, optical absorption coefficient, and the estimated photovoltaic conversion efficiency, performed data analysis and co-wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6009434	30009012	M.Z.	2	performed calculations of phonon dispersion, and elastic constants, performed data analysis and co-edit the manuscript	performed calculations of phonon dispersion, and elastic constants, performed data analysis and co-edit the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
6009434	30009012	P.F.P.P.	2	conceived the experiment, performed crystal structure measurement, analyzed the results and co-wrote the manuscript	conceived the experiment, performed crystal structure measurement, analyzed the results and co-wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
4412726	25919662	AD	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412726	25919662	AK	PLoS5	Constructive suggestions on clinical sides	Constructive suggestions on clinical sides	Performed the experiments	Investigation	YES
4412726	25919662	IY	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412726	25919662	RL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412726	25919662	RL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412726	25919662	RL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412726	25919662	RL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412726	25919662	RP	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412726	25919662	RP	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412726	25919662	RP	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412726	25919662	SF	PLoS5	Constructive suggestions on clinical sides	Constructive suggestions on clinical sides	Performed the experiments	Investigation	YES
4412726	25919662	SK	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412726	25919662	SK	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5331170	28293668	Emmanuel Alote Allotey	PLoS52	conceptualized and designed the study|recruited participants and generated the data|analyzed the data|drafted the manuscript|reviewed the manuscript for intellectual content and each author approved the final manuscript	conceptualized and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5331170	28293668	Emmanuel Alote Allotey	PLoS52	conceptualized and designed the study|recruited participants and generated the data|analyzed the data|drafted the manuscript|reviewed the manuscript for intellectual content and each author approved the final manuscript	recruited participants and generated the data	Performed the experiments	Investigation	YES
5331170	28293668	Emmanuel Alote Allotey	PLoS52	conceptualized and designed the study|recruited participants and generated the data|analyzed the data|drafted the manuscript|reviewed the manuscript for intellectual content and each author approved the final manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5331170	28293668	Emmanuel Alote Allotey	PLoS52	conceptualized and designed the study|recruited participants and generated the data|analyzed the data|drafted the manuscript|reviewed the manuscript for intellectual content and each author approved the final manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5331170	28293668	Emmanuel Alote Allotey	PLoS52	conceptualized and designed the study|recruited participants and generated the data|analyzed the data|drafted the manuscript|reviewed the manuscript for intellectual content and each author approved the final manuscript	reviewed the manuscript for intellectual content and each author approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5331170	28293668	Florence A. Attah	PLoS52	conceptualized and designed the study|recruited participants and generated the data|drafted the manuscript|reviewed the manuscript for intellectual content and each author approved the final manuscript	conceptualized and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5331170	28293668	Florence A. Attah	PLoS52	conceptualized and designed the study|recruited participants and generated the data|drafted the manuscript|reviewed the manuscript for intellectual content and each author approved the final manuscript	recruited participants and generated the data	Performed the experiments	Investigation	YES
5331170	28293668	Florence A. Attah	PLoS52	conceptualized and designed the study|recruited participants and generated the data|drafted the manuscript|reviewed the manuscript for intellectual content and each author approved the final manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5331170	28293668	Florence A. Attah	PLoS52	conceptualized and designed the study|recruited participants and generated the data|drafted the manuscript|reviewed the manuscript for intellectual content and each author approved the final manuscript	reviewed the manuscript for intellectual content and each author approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5331170	28293668	Gameli Kwame Norgbe	PLoS52	conceptualized and designed the study|analyzed the data|drafted the manuscript|reviewed the manuscript for intellectual content and each author approved the final manuscript	conceptualized and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5331170	28293668	Gameli Kwame Norgbe	PLoS52	conceptualized and designed the study|analyzed the data|drafted the manuscript|reviewed the manuscript for intellectual content and each author approved the final manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5331170	28293668	Gameli Kwame Norgbe	PLoS52	conceptualized and designed the study|analyzed the data|drafted the manuscript|reviewed the manuscript for intellectual content and each author approved the final manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5331170	28293668	Gameli Kwame Norgbe	PLoS52	conceptualized and designed the study|analyzed the data|drafted the manuscript|reviewed the manuscript for intellectual content and each author approved the final manuscript	reviewed the manuscript for intellectual content and each author approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5331170	28293668	James Osei-Yeboah	PLoS52	recruited participants and generated the data	recruited participants and generated the data	Performed the experiments	Investigation	YES
5331170	28293668	Jones Gyamfi	PLoS52	conceptualized and designed the study|analyzed the data|drafted the manuscript|reviewed the manuscript for intellectual content and each author approved the final manuscript	conceptualized and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5331170	28293668	Jones Gyamfi	PLoS52	conceptualized and designed the study|analyzed the data|drafted the manuscript|reviewed the manuscript for intellectual content and each author approved the final manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5331170	28293668	Jones Gyamfi	PLoS52	conceptualized and designed the study|analyzed the data|drafted the manuscript|reviewed the manuscript for intellectual content and each author approved the final manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5331170	28293668	Jones Gyamfi	PLoS52	conceptualized and designed the study|analyzed the data|drafted the manuscript|reviewed the manuscript for intellectual content and each author approved the final manuscript	reviewed the manuscript for intellectual content and each author approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5331170	28293668	K. B. A. Owiredu	PLoS52	conceptualized and designed the study|analyzed the data|drafted the manuscript|reviewed the manuscript for intellectual content and each author approved the final manuscript	conceptualized and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5331170	28293668	K. B. A. Owiredu	PLoS52	conceptualized and designed the study|analyzed the data|drafted the manuscript|reviewed the manuscript for intellectual content and each author approved the final manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5331170	28293668	K. B. A. Owiredu	PLoS52	conceptualized and designed the study|analyzed the data|drafted the manuscript|reviewed the manuscript for intellectual content and each author approved the final manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5331170	28293668	K. B. A. Owiredu	PLoS52	conceptualized and designed the study|analyzed the data|drafted the manuscript|reviewed the manuscript for intellectual content and each author approved the final manuscript	reviewed the manuscript for intellectual content and each author approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5331170	28293668	Mark Noagbe	PLoS52	conceptualized and designed the study|recruited participants and generated the data|drafted the manuscript|reviewed the manuscript for intellectual content and each author approved the final manuscript	conceptualized and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5331170	28293668	Mark Noagbe	PLoS52	conceptualized and designed the study|recruited participants and generated the data|drafted the manuscript|reviewed the manuscript for intellectual content and each author approved the final manuscript	recruited participants and generated the data	Performed the experiments	Investigation	YES
5331170	28293668	Mark Noagbe	PLoS52	conceptualized and designed the study|recruited participants and generated the data|drafted the manuscript|reviewed the manuscript for intellectual content and each author approved the final manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5331170	28293668	Mark Noagbe	PLoS52	conceptualized and designed the study|recruited participants and generated the data|drafted the manuscript|reviewed the manuscript for intellectual content and each author approved the final manuscript	reviewed the manuscript for intellectual content and each author approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5331170	28293668	Romeo Asumbasiya Aduko	PLoS52	conceptualized and designed the study|recruited participants and generated the data|analyzed the data|drafted the manuscript|reviewed the manuscript for intellectual content and each author approved the final manuscript	conceptualized and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5331170	28293668	Romeo Asumbasiya Aduko	PLoS52	conceptualized and designed the study|recruited participants and generated the data|analyzed the data|drafted the manuscript|reviewed the manuscript for intellectual content and each author approved the final manuscript	recruited participants and generated the data	Performed the experiments	Investigation	YES
5331170	28293668	Romeo Asumbasiya Aduko	PLoS52	conceptualized and designed the study|recruited participants and generated the data|analyzed the data|drafted the manuscript|reviewed the manuscript for intellectual content and each author approved the final manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5331170	28293668	Romeo Asumbasiya Aduko	PLoS52	conceptualized and designed the study|recruited participants and generated the data|analyzed the data|drafted the manuscript|reviewed the manuscript for intellectual content and each author approved the final manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5331170	28293668	Romeo Asumbasiya Aduko	PLoS52	conceptualized and designed the study|recruited participants and generated the data|analyzed the data|drafted the manuscript|reviewed the manuscript for intellectual content and each author approved the final manuscript	reviewed the manuscript for intellectual content and each author approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5331170	28293668	Sylvester Yao Lokpo	PLoS52	conceptualized and designed the study|recruited participants and generated the data|analyzed the data|drafted the manuscript|reviewed the manuscript for intellectual content and each author approved the final manuscript	conceptualized and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5331170	28293668	Sylvester Yao Lokpo	PLoS52	conceptualized and designed the study|recruited participants and generated the data|analyzed the data|drafted the manuscript|reviewed the manuscript for intellectual content and each author approved the final manuscript	recruited participants and generated the data	Performed the experiments	Investigation	YES
5331170	28293668	Sylvester Yao Lokpo	PLoS52	conceptualized and designed the study|recruited participants and generated the data|analyzed the data|drafted the manuscript|reviewed the manuscript for intellectual content and each author approved the final manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5331170	28293668	Sylvester Yao Lokpo	PLoS52	conceptualized and designed the study|recruited participants and generated the data|analyzed the data|drafted the manuscript|reviewed the manuscript for intellectual content and each author approved the final manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5331170	28293668	Sylvester Yao Lokpo	PLoS52	conceptualized and designed the study|recruited participants and generated the data|analyzed the data|drafted the manuscript|reviewed the manuscript for intellectual content and each author approved the final manuscript	reviewed the manuscript for intellectual content and each author approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5607050	28933018	CC	CRediT2	handled biopsy and surgery	handled biopsy and surgery	Performed the experiments	Investigation	YES
5607050	28933018	LMW	CRediT2	reported tumour regression grade	reported tumour regression grade	Analyzed the data	Formal analysis	YES
5607050	28933018	MP	CRediT2	contributed to conceptualization and study design	contributed to conceptualization and study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5607050	28933018	PET	CRediT2	data analysis, statistics and interpretation, wrote the manuscript and critically contributed to the manuscript	data analysis, statistics and interpretation, wrote the manuscript and critically contributed to the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5607050	28933018	ROIs	CRediT2	data analysis, statistics and interpretation, wrote the manuscript and critically contributed to the manuscript|reported clinical response, helped in project administration and wrote the manuscript|project administration	data analysis, statistics and interpretation, wrote the manuscript and critically contributed to the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5607050	28933018	ROIs	CRediT2	data analysis, statistics and interpretation, wrote the manuscript and critically contributed to the manuscript|reported clinical response, helped in project administration and wrote the manuscript|project administration	reported clinical response, helped in project administration and wrote the manuscript	Wrote the paper	Project administration|Writing - Original Draft	YES
5607050	28933018	ROIs	CRediT2	data analysis, statistics and interpretation, wrote the manuscript and critically contributed to the manuscript|reported clinical response, helped in project administration and wrote the manuscript|project administration	project administration	-	Project administration	YES
5607050	28933018	TM	CRediT2	is the principal investigator, contributed to conceptualization and study design, reported clinical response and critically contributed to the manuscript	is the principal investigator, contributed to conceptualization and study design, reported clinical response and critically contributed to the manuscript	Conceived and designed the experiments	Conceptualization|Funding acquisition|Methodology	YES
5607050	28933018	VS	CRediT2	contributed to patient characteristics table	contributed to patient characteristics table	Performed the experiments	Investigation	YES
5563009	28821226	All the authors	2	contributed to the manuscript revision	contributed to the manuscript revision	Wrote the paper	Writing - Review & Editing	YES
5563009	28821226	CD	2	performed the experimental work	performed the experimental work	Performed the experiments	Investigation	YES
5563009	28821226	CVM	2	conceived the project and the sampling design|wrote the first draft of the manuscript	conceived the project and the sampling design	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
5563009	28821226	CVM	2	conceived the project and the sampling design|wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
5563009	28821226	FHT	2	performed the experimental work	performed the experimental work	Performed the experiments	Investigation	YES
5563009	28821226	JWD	2	performed the experimental work	performed the experimental work	Performed the experiments	Investigation	YES
5563009	28821226	PM	2	conceived the project and the sampling design|wrote the first draft of the manuscript	conceived the project and the sampling design	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
5563009	28821226	PM	2	conceived the project and the sampling design|wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
5563009	28821226	PP	2	performed the experimental work	performed the experimental work	Performed the experiments	Investigation	YES
5563009	28821226	VG	2	performed the experimental work	performed the experimental work	Performed the experiments	Investigation	YES
5563009	28821226	YS	2	conceived the project and the sampling design|performed the experimental work|performed the bioinformatics and statistical analyses|wrote the first draft of the manuscript	conceived the project and the sampling design	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
5563009	28821226	YS	2	conceived the project and the sampling design|performed the experimental work|performed the bioinformatics and statistical analyses|wrote the first draft of the manuscript	performed the experimental work	Performed the experiments	Investigation	YES
5563009	28821226	YS	2	conceived the project and the sampling design|performed the experimental work|performed the bioinformatics and statistical analyses|wrote the first draft of the manuscript	performed the bioinformatics and statistical analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5563009	28821226	YS	2	conceived the project and the sampling design|performed the experimental work|performed the bioinformatics and statistical analyses|wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
3407494	22510233	FM	2	designed the study|conducted data analysis	designed the study	Conceived and designed the experiments	Methodology	YES
3407494	22510233	FM	2	designed the study|conducted data analysis	conducted data analysis	Analyzed the data	Formal analysis	YES
3407494	22510233	HM	2	designed the study|collected the data|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
3407494	22510233	HM	2	designed the study|collected the data|wrote the manuscript	collected the data	Performed the experiments	Investigation	YES
3407494	22510233	HM	2	designed the study|collected the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3407494	22510233	MS	2	designed the study|collected the data|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
3407494	22510233	MS	2	designed the study|collected the data|wrote the manuscript	collected the data	Performed the experiments	Investigation	YES
3407494	22510233	MS	2	designed the study|collected the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3407494	22510233	TM	2	is the principal investigator of the project|wrote the manuscript	is the principal investigator of the project	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
3407494	22510233	TM	2	is the principal investigator of the project|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3407494	22510233	YT	2	designed the study|conducted data analysis	designed the study	Conceived and designed the experiments	Methodology	YES
3407494	22510233	YT	2	designed the study|conducted data analysis	conducted data analysis	Analyzed the data	Formal analysis	YES
5574264	28894787	IRB	2	approval, conducted the data analysis, and wrote the manuscript	approval, conducted the data analysis, and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
1868780	17534422	BL	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1868780	17534422	BL	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1868780	17534422	SA	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1868780	17534422	SA	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5615083	28952076	All authors	2	revised former versions of the manuscript, and they read and approved the final manuscript	revised former versions of the manuscript, and they read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5615083	28952076	MHV	2	provided the data from her clinical study	provided the data from her clinical study	Contributed reagents/materials/analysis tools	Resources	YES
5615083	28952076	OG	2	designed the study, conducted the statistical analyses, and drafted the manuscript	designed the study, conducted the statistical analyses, and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5615083	28952076	PFHC	2	contributed to the interpretation of the findings	contributed to the interpretation of the findings	Analyzed the data	Formal analysis	YES
5615083	28952076	UH	2	discussed statistical analyses and participated in data interpretation	discussed statistical analyses and participated in data interpretation	Analyzed the data	Formal analysis	YES
5702339	29209345	AA	1	Experimental conducting, planning and writing	Experimental conducting, planning and writing	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology	YES
5702339	29209345	GL	1	Conception, planning, and revision	Conception, planning, and revision	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
5702339	29209345	J-LC	1	Writing input and revision	Writing input and revision	Wrote the paper	Writing - Review & Editing	YES
5702339	29209345	KL	1	Writing input and revision	Writing input and revision	Wrote the paper	Writing - Review & Editing	YES
5702339	29209345	KW	1	Writing input and revision	Writing input and revision	Wrote the paper	Writing - Review & Editing	YES
5702339	29209345	VR-N	1	Writing input and revision	Writing input and revision	Wrote the paper	Writing - Review & Editing	YES
4524883	26243173	All authors	2	have equally contributed to this work and have read and approved the final manuscript	have equally contributed to this work and have read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
3407721	22713127	AP	2	contributed to data collection and analysis	contributed to data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3407721	22713127	EC	2	were responsible for the patients recruitment and data collection	were responsible for the patients recruitment and data collection	Performed the experiments	Investigation	YES
3407721	22713127	FF	2	were responsible for the patients recruitment and data collection	were responsible for the patients recruitment and data collection	Performed the experiments	Investigation	YES
3407721	22713127	FP	2	contributed to the study design, was responsible for the final approval of the manuscript	contributed to the study design, was responsible for the final approval of the manuscript	Conceived and designed the experiments	Methodology	YES
3407721	22713127	FQ	2	were responsible for the patients recruitment and data collection	were responsible for the patients recruitment and data collection	Performed the experiments	Investigation	YES
3407721	22713127	MR	2	contributed to the design of the study and the preparation of the manuscript	contributed to the design of the study and the preparation of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3407721	22713127	PB	2	was responsible for the conception and design of the study as well as the preparation of the manuscript	was responsible for the conception and design of the study as well as the preparation of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
4412803	25919285	CCC	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412803	25919285	CCC	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412803	25919285	CCC	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412803	25919285	CCC	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412803	25919285	LCL	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412803	25919285	SPL	PLoS5	Wrote the paper|Manuscript preparation and review	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412803	25919285	SPL	PLoS5	Wrote the paper|Manuscript preparation and review	Manuscript preparation and review	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4412803	25919285	YWL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412803	25919285	YWL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412803	25919285	YWL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412803	25919285	YWL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412803	25919285	YWL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5563022	28821240	CM	2	carried out the ihc	carried out the ihc	Performed the experiments	Investigation	YES
5563022	28821240	JH	2	participated in the design and coordination of the study|drafted the manuscript	participated in the design and coordination of the study	Conceived and designed the experiments	Methodology|Project administration	YES
5563022	28821240	JH	2	participated in the design and coordination of the study|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5563022	28821240	KC	2	performed analyses of microbiota data	performed analyses of microbiota data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5563022	28821240	KW	2	participated in the design and coordination of the study	participated in the design and coordination of the study	Conceived and designed the experiments	Methodology|Project administration	YES
5563022	28821240	RB	2	performed analyses of microbiota data|participated in the design and coordination of the study	performed analyses of microbiota data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5563022	28821240	RB	2	performed analyses of microbiota data|participated in the design and coordination of the study	participated in the design and coordination of the study	Conceived and designed the experiments	Methodology|Project administration	YES
5563022	28821240	SSN	2	carried out the cd, permeabilisation and structural modelling analyses	carried out the cd, permeabilisation and structural modelling analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5563022	28821240	VLA	2	identified the snps and carried out the genotyping studies	identified the snps and carried out the genotyping studies	Performed the experiments	Investigation	YES
4600871	26491668	Dong Ju Son	PLoS52	analyzed and interpreted the data and wrote the paper	analyzed and interpreted the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4600871	26491668	Dong Won Lee	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
4600871	26491668	Hye Lim Lee	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
4600871	26491668	Jae Yeon Hwang	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
4600871	26491668	Ji Eun Hong	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
4600871	26491668	Jin Tae Hong	PLoS52	supervised the overall research, designed the experiments, secured funding, and had primary responsibility for final content	supervised the overall research, designed the experiments, secured funding, and had primary responsibility for final content	Conceived and designed the experiments	Funding acquisition|Methodology|Supervision	YES
4600871	26491668	Jung Ok Ban	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
4600871	26491668	Myung Hee Jung	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
4600871	26491668	Sang-Bae Han	PLoS52	analyzed and interpreted the data and wrote the paper	analyzed and interpreted the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4600871	26491668	Sun Mi Gu	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
4529425	26253391	All authors	2	had participated equally|read and approved the final manuscript	had participated equally	-	-	NO
4529425	26253391	All authors	2	had participated equally|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4529425	26253391	The authors	2	declared that they have no competing interests	declared that they have no competing interests	-	-	NO
1868781	17534433	CE	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1868781	17534433	CM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1868781	17534433	CM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1868781	17534433	CM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1868781	17534433	CM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1868781	17534433	CM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1868781	17534433	GG	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1868781	17534433	HS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1868781	17534433	HS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1868781	17534433	HS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1868781	17534433	RH	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1868781	17534433	RH	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1868781	17534433	VA	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4412812	25918848	HN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412812	25918848	HN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412812	25918848	HN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412812	25918848	HN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412812	25918848	HN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412812	25918848	KT	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412812	25918848	KT	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412812	25918848	NS	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412812	25918848	NS	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412812	25918848	SI	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412812	25918848	SI	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412812	25918848	SI	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412812	25918848	SI	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412812	25918848	YI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412812	25918848	YI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412812	25918848	YI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412812	25918848	YI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412812	25918848	YI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412812	25918848	YO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412812	25918848	YO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412812	25918848	YO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412812	25918848	YO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412812	25918848	YO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5702354	29209343	All the authors	2	discussed the results and commented on the manuscript	discussed the results and commented on the manuscript	-	-	NO
5702354	29209343	FZ	2	performed the experiment, collected the samples and collected the data	performed the experiment, collected the samples and collected the data	Performed the experiments	Investigation	YES
5702354	29209343	GZ	2	assisted to manage the experiment and collect the data	assisted to manage the experiment and collect the data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5702354	29209343	LY	2	designed the experiments, revised the manuscript and applied funding to support the study	designed the experiments, revised the manuscript and applied funding to support the study	Conceived and designed the experiments|Wrote the paper	Funding acquisition|Methodology|Writing - Review & Editing	YES
5702354	29209343	X-XW	2	analyzed the data, wrote the first manuscript and modified it	analyzed the data, wrote the first manuscript and modified it	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5702354	29209343	YZ	2	assisted to manage the experiment and collect the data	assisted to manage the experiment and collect the data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5563062	28821238	AC	PLoS52	conceived and the study|wrote the paper	conceived and the study	Conceived and designed the experiments	Conceptualization	YES
5563062	28821238	AC	PLoS52	conceived and the study|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5563062	28821238	FM	PLoS52	conceived and the study|designed the study|performed bioinformatics analyses|wrote the paper	conceived and the study	Conceived and designed the experiments	Conceptualization	YES
5563062	28821238	FM	PLoS52	conceived and the study|designed the study|performed bioinformatics analyses|wrote the paper	designed the study	Conceived and designed the experiments	Methodology	YES
5563062	28821238	FM	PLoS52	conceived and the study|designed the study|performed bioinformatics analyses|wrote the paper	performed bioinformatics analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5563062	28821238	FM	PLoS52	conceived and the study|designed the study|performed bioinformatics analyses|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5563062	28821238	LN	PLoS52	conceived and the study|wrote the paper	conceived and the study	Conceived and designed the experiments	Conceptualization	YES
5563062	28821238	LN	PLoS52	conceived and the study|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5563062	28821238	MC	PLoS52	performed cytological analyses|wrote the paper	performed cytological analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5563062	28821238	MC	PLoS52	performed cytological analyses|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5563062	28821238	PRIN-MIUR	PLoS52	project and coordinator of the study	project and coordinator of the study	-	Project administration	YES
5563062	28821238	SUNREP	PLoS52	project and coordinator of the study	project and coordinator of the study	-	Project administration	YES
5563062	28821238	TG	PLoS52	designed the study|performed bioinformatics analyses|performed molecular analyses|wrote the paper	designed the study	Conceived and designed the experiments	Methodology	YES
5563062	28821238	TG	PLoS52	designed the study|performed bioinformatics analyses|performed molecular analyses|wrote the paper	performed bioinformatics analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5563062	28821238	TG	PLoS52	designed the study|performed bioinformatics analyses|performed molecular analyses|wrote the paper	performed molecular analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5563062	28821238	TG	PLoS52	designed the study|performed bioinformatics analyses|performed molecular analyses|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5654269	29130065	Akosua Adom Agyeman	2	contributed to data extraction and manuscript revision	contributed to data extraction and manuscript revision	Analyzed the data|Wrote the paper	Data curation|Writing - Review & Editing	YES
5654269	29130065	Amos Laar	2	provided critical inputs into the manuscript revision	provided critical inputs into the manuscript revision	Wrote the paper	Writing - Review & Editing	YES
5654269	29130065	Richard Ofori-Asenso	2	carried out the literature search, conducted the analysis, and drafted the manuscript	carried out the literature search, conducted the analysis, and drafted the manuscript	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5624857	28971329	AC	2	contributed to the data collection	contributed to the data collection	Performed the experiments	Investigation	YES
5624857	28971329	ASB	2	contributed to the study conception, data collection, data analysis, and drafting of the manuscript	contributed to the study conception, data collection, data analysis, and drafting of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Resources|Writing - Original Draft	YES
5624857	28971329	JIE	2	contributed to the data collection and data analysis	contributed to the data collection and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5624857	28971329	LBS	2	was involved in the data collection and data analysis	was involved in the data collection and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5624857	28971329	MAG	2	contributed to the study conception, data collection, data analysis, securing the funding, and drafting of the manuscript	contributed to the study conception, data collection, data analysis, securing the funding, and drafting of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Funding acquisition|Investigation|Resources|Writing - Original Draft	YES
5624857	28971329	MEA	2	contributed to the study conception and securing the funding	contributed to the study conception and securing the funding	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
5624857	28971329	MSJ	2	contributed to the data collection and data analysis	contributed to the data collection and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5624857	28971329	MWB	2	contributed to the data collection and data analysis	contributed to the data collection and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5624857	28971329	PMP	2	contributed to the data collection and data analysis	contributed to the data collection and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5624857	28971329	SPR	2	contributed to the study conception, data collection, data analysis, and drafting of the manuscript	contributed to the study conception, data collection, data analysis, and drafting of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Resources|Writing - Original Draft	YES
3407788	22817979	All authors	2	have read, reviewed and contributed to the final manuscript	have read, reviewed and contributed to the final manuscript	Wrote the paper	Writing - Review & Editing	YES
1868782	17534435	AA	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1868782	17534435	AA	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1868782	17534435	CD	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1868782	17534435	CD	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1868782	17534435	ED	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Obtained funding for the study	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1868782	17534435	ED	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Obtained funding for the study	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1868782	17534435	ED	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Obtained funding for the study	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1868782	17534435	ED	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Obtained funding for the study	Obtained funding for the study	-	Funding acquisition	YES
1868782	17534435	FH	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1868782	17534435	FH	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1868782	17534435	MS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1868782	17534435	MS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1868782	17534435	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1868782	17534435	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1868782	17534435	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1868782	17534435	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1868782	17534435	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412813	25919488	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412813	25919488	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412813	25919488	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412813	25919488	JP	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412813	25919488	JP	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412813	25919488	RP	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412813	25919488	RP	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5687143	29226217	Atsbeha Gebreegziabxier	2	participated in laboratory tests	participated in laboratory tests	Performed the experiments	Investigation	YES
5687143	29226217	Desta Kassa	2	were involved during data analysis and in writing during the draft interim and final version of the manuscript	were involved during data analysis and in writing during the draft interim and final version of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5687143	29226217	Feyissa Challa	2	participated in laboratory tests	participated in laboratory tests	Performed the experiments	Investigation	YES
5687143	29226217	Gebremedhin Gebremicael	2	were lead authors in planning, implementation of the study, data analysis, writing of the draft, and final version of the manuscript	were lead authors in planning, implementation of the study, data analysis, writing of the draft, and final version of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5687143	29226217	Girmay Medhin	2	were involved during data analysis and in writing during the draft interim and final version of the manuscript	were involved during data analysis and in writing during the draft interim and final version of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5687143	29226217	Mistire Wolde	2	were involved during data analysis and in writing during the draft interim and final version of the manuscript	were involved during data analysis and in writing during the draft interim and final version of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5687143	29226217	Yemane Amare	2	were lead authors in planning, implementation of the study, data analysis, writing of the draft, and final version of the manuscript	were lead authors in planning, implementation of the study, data analysis, writing of the draft, and final version of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4531121	26260895	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4531121	26260895	DM	2	provided the isolates and critical revision of the manuscript	provided the isolates and critical revision of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4531121	26260895	ES	2	provided the isolates and critical revision of the manuscript	provided the isolates and critical revision of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4531121	26260895	JA	2	developed analytical tool and drafted the manuscript	developed analytical tool and drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4531121	26260895	LMI	2	supervised the work, gave conceptual advices, collected the african strains, and drafted the manuscript	supervised the work, gave conceptual advices, collected the african strains, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Supervision|Writing - Original Draft	YES
4531121	26260895	RBC	2	provided the isolates and critical revision of the manuscript	provided the isolates and critical revision of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4531121	26260895	YD	2	designed and performed experiments, analyzed data and drafted the manuscript	designed and performed experiments, analyzed data and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
1868783	17534426	NT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1868783	17534426	NT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1868783	17534426	NT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1868783	17534426	NT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1868783	17534426	NT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1868783	17534426	OK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1868783	17534426	OK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1868783	17534426	OK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1868783	17534426	OK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1868783	17534426	OK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5563889	28826405	AP	2	performed bioinformatic analyses of the data sets	performed bioinformatic analyses of the data sets	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5563889	28826405	DLV	2	planned the experiments	planned the experiments	Conceived and designed the experiments	Conceptualization	YES
5563889	28826405	JAS	2	planned the experiments|wrote the manuscript	planned the experiments	Conceived and designed the experiments	Conceptualization	YES
5563889	28826405	JAS	2	planned the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5563889	28826405	JIY	2	performed bioinformatic analyses of the data sets	performed bioinformatic analyses of the data sets	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5563889	28826405	JKH	2	performed the sequencing|performed bioinformatic analyses of the data sets	performed the sequencing	Performed the experiments	Investigation	YES
5563889	28826405	JKH	2	performed the sequencing|performed bioinformatic analyses of the data sets	performed bioinformatic analyses of the data sets	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5563889	28826405	JZC	2	performed bioinformatic analyses of the data sets	performed bioinformatic analyses of the data sets	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5563889	28826405	KVS	2	performed bioinformatic analyses of the data sets	performed bioinformatic analyses of the data sets	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5563889	28826405	LMH	2	performed bioinformatic analyses of the data sets	performed bioinformatic analyses of the data sets	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5563889	28826405	MAO	2	planned the experiments|wrote the manuscript	planned the experiments	Conceived and designed the experiments	Conceptualization	YES
5563889	28826405	MAO	2	planned the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5563889	28826405	SPG	2	planned the experiments|cultured and isolated dna|performed the sequencing|performed growth and metabolite analyses|performed bioinformatic analyses of the data sets|wrote the manuscript	planned the experiments	Conceived and designed the experiments	Conceptualization	YES
5563889	28826405	SPG	2	planned the experiments|cultured and isolated dna|performed the sequencing|performed growth and metabolite analyses|performed bioinformatic analyses of the data sets|wrote the manuscript	cultured and isolated dna	Performed the experiments	Investigation	YES
5563889	28826405	SPG	2	planned the experiments|cultured and isolated dna|performed the sequencing|performed growth and metabolite analyses|performed bioinformatic analyses of the data sets|wrote the manuscript	performed the sequencing	Performed the experiments	Investigation	YES
5563889	28826405	SPG	2	planned the experiments|cultured and isolated dna|performed the sequencing|performed growth and metabolite analyses|performed bioinformatic analyses of the data sets|wrote the manuscript	performed growth and metabolite analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5563889	28826405	SPG	2	planned the experiments|cultured and isolated dna|performed the sequencing|performed growth and metabolite analyses|performed bioinformatic analyses of the data sets|wrote the manuscript	performed bioinformatic analyses of the data sets	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5563889	28826405	SPG	2	planned the experiments|cultured and isolated dna|performed the sequencing|performed growth and metabolite analyses|performed bioinformatic analyses of the data sets|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5563889	28826405	SS	2	performed bioinformatic analyses of the data sets	performed bioinformatic analyses of the data sets	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5563889	28826405	VK	2	cultured and isolated dna	cultured and isolated dna	Performed the experiments	Investigation	YES
5563889	28826405	XP	2	performed growth and metabolite analyses	performed growth and metabolite analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5563889	28826405	YT	2	planned the experiments|performed the sequencing	planned the experiments	Conceived and designed the experiments	Conceptualization	YES
5563889	28826405	YT	2	planned the experiments|performed the sequencing	performed the sequencing	Performed the experiments	Investigation	YES
3409051	22812729	BA	2	participated in the blood analysis measurements	participated in the blood analysis measurements	Performed the experiments	Investigation	YES
3409051	22812729	DE	2	participated in the nutrition analysis	participated in the nutrition analysis	-	-	NO
3409051	22812729	GL	2	carried out the recollection of the data, designed the dietary booklet and drafted the manuscript	carried out the recollection of the data, designed the dietary booklet and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3409051	22812729	GS	2	conceived of the study, and participated in its design and coordination and helped to draft the manuscript	conceived of the study, and participated in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
3409051	22812729	IJ	2	participated in the design of the study and performed the statistical analysis	participated in the design of the study and performed the statistical analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
3409051	22812729	LJ	2	participated in the blood analysis measurements and coordination of the study	participated in the blood analysis measurements and coordination of the study	Performed the experiments	Investigation|Project administration	YES
3409051	22812729	RF	2	carried out the antioxidant analysis	carried out the antioxidant analysis	Performed the experiments	Investigation	YES
5626671	28975570	AI	2	contributed to the preparation of the study and critical revision of the manuscript	contributed to the preparation of the study and critical revision of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5626671	28975570	AK	2	contributed to explaining the study concept to patients and obtaining informed consent from them	contributed to explaining the study concept to patients and obtaining informed consent from them	Conceived and designed the experiments	Conceptualization|Project administration	YES
5626671	28975570	JF	2	contributed to explaining the study concept to patients and obtaining informed consent from them	contributed to explaining the study concept to patients and obtaining informed consent from them	Conceived and designed the experiments	Conceptualization|Project administration	YES
5626671	28975570	KI	2	contributed to the critical revision of the manuscript	contributed to the critical revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5626671	28975570	KN	2	contributed to phantom data collection	contributed to phantom data collection	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5626671	28975570	MF	2	contributed to the critical revision of the manuscript	contributed to the critical revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5626671	28975570	MJ	2	contributed to the critical revision of the manuscript	contributed to the critical revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5626671	28975570	MM	2	contributed to phantom data collection	contributed to phantom data collection	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5626671	28975570	MO	2	contributed to explaining the study concept to patients and obtaining informed consent from them	contributed to explaining the study concept to patients and obtaining informed consent from them	Conceived and designed the experiments	Conceptualization|Project administration	YES
5626671	28975570	TK	2	contributed to explaining the study concept to patients and obtaining informed consent from them	contributed to explaining the study concept to patients and obtaining informed consent from them	Conceived and designed the experiments	Conceptualization|Project administration	YES
5626671	28975570	TN	2	contributed to the study design, analysis of the data, and draft and critical revision of the manuscript	contributed to the study design, analysis of the data, and draft and critical revision of the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5626671	28975570	YO	2	contributed to the study design, phantom data collection and analysis of the data	contributed to the study design, phantom data collection and analysis of the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Methodology|Resources	YES
5702422	29209340	AR	2	interpreted the results	interpreted the results	Analyzed the data	Formal analysis	YES
5702422	29209340	All authors	2	have read and approved the manuscript for publication	have read and approved the manuscript for publication	-	-	NO
5702422	29209340	BS	2	conceived the idea of the study and drafting the manuscript	conceived the idea of the study and drafting the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5702422	29209340	DM	2	interpreted the results|conceived the idea of the study and drafting the manuscript	interpreted the results	Analyzed the data	Formal analysis	YES
5702422	29209340	DM	2	interpreted the results|conceived the idea of the study and drafting the manuscript	conceived the idea of the study and drafting the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5702422	29209340	IS	2	initiated the research, performed the downstream analyses, interpreted the results and drafted the manuscript|interpreted the results	initiated the research, performed the downstream analyses, interpreted the results and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
5702422	29209340	IS	2	initiated the research, performed the downstream analyses, interpreted the results and drafted the manuscript|interpreted the results	interpreted the results	Analyzed the data	Formal analysis	YES
5702422	29209340	SK	2	interpreted the results|conceived the idea of the study and drafting the manuscript	interpreted the results	Analyzed the data	Formal analysis	YES
5702422	29209340	SK	2	interpreted the results|conceived the idea of the study and drafting the manuscript	conceived the idea of the study and drafting the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5702422	29209340	SS	2	initiated the research, performed the downstream analyses, interpreted the results and drafted the manuscript|interpreted the results	initiated the research, performed the downstream analyses, interpreted the results and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
5702422	29209340	SS	2	initiated the research, performed the downstream analyses, interpreted the results and drafted the manuscript|interpreted the results	interpreted the results	Analyzed the data	Formal analysis	YES
4412816	25919813	CCS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412816	25919813	CCS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412816	25919813	CCS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412816	25919813	CCS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412816	25919813	CJY	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412816	25919813	CJY	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412816	25919813	CLH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4412816	25919813	CYL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4412816	25919813	FJY	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4412816	25919813	JTW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4412816	25919813	JYW	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412816	25919813	JYW	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412816	25919813	JYW	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412816	25919813	LNL	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412816	25919813	LNL	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412816	25919813	VCW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
3411406	22835211	A Palma	2	participated in the design of the study and helped to draft the manuscript	participated in the design of the study and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3411406	22835211	A Paoli	2	was the main researcher and was responsible for study design, statistical analysis and interpretation of data and draft of manuscript, conceived the study, participated in its design, drafted the manuscript and performed the statistical analysis	was the main researcher and was responsible for study design, statistical analysis and interpretation of data and draft of manuscript, conceived the study, participated in its design, drafted the manuscript and performed the statistical analysis	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
3411406	22835211	AB	2	participated in the design of the study and in the statistical analysis	participated in the design of the study and in the statistical analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
3411406	22835211	CB	2	was responsible for study design and acquisition of data	was responsible for study design and acquisition of data	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3411406	22835211	DA	2	participated in the study design and coordination and helped to draft the manuscript	participated in the study design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft	YES
3411406	22835211	KG	2	was responsible for analysis and interpretation of data and helped to draft the manuscript	was responsible for analysis and interpretation of data and helped to draft the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3411406	22835211	LC	2	was responsible for diet prescription and analysis	was responsible for diet prescription and analysis	-	-	NO
3411406	22835211	TM	2	helped to draft the manuscript	helped to draft the manuscript	Wrote the paper	Writing - Original Draft	YES
3411480	22780983	MO	2	was responsible for literature review and manuscript preparation	was responsible for literature review and manuscript preparation	Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
3411480	22780983	SMO	2	was responsible for the study design, biochemical work, statistical analyses, and manuscript preparation	was responsible for the study design, biochemical work, statistical analyses, and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4531123	26260894	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4531123	26260894	HYL	2	conceived experiments|wrote the manuscript	conceived experiments	Conceived and designed the experiments	Conceptualization	YES
4531123	26260894	HYL	2	conceived experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4531123	26260894	JSC	2	conducted experiments	conducted experiments	Performed the experiments	Investigation	YES
4531123	26260894	NYK	2	conducted experiments|wrote the manuscript	conducted experiments	Performed the experiments	Investigation	YES
4531123	26260894	NYK	2	conducted experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4531123	26260894	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5702424	29209347	The author	2	confirms being the sole contributor of this work and approved it for publication	confirms being the sole contributor of this work and approved it for publication	-	-	NO
5563900	28826393	AMD	1	Performed data analysis|Interpretation of results	Performed data analysis	Analyzed the data	Formal analysis	YES
5563900	28826393	AMD	1	Performed data analysis|Interpretation of results	Interpretation of results	Analyzed the data	Formal analysis	YES
5563900	28826393	JQY	1	Performed wet lab experiments	Performed wet lab experiments	Performed the experiments	Investigation	YES
5563900	28826393	WL	1	Interpretation of results	Interpretation of results	Analyzed the data	Formal analysis	YES
5563900	28826393	YMW	1	Interpretation of results	Interpretation of results	Analyzed the data	Formal analysis	YES
5563900	28826393	ZWJ	1	Performed wet lab experiments|Interpretation of results	Performed wet lab experiments	Performed the experiments	Investigation	YES
5563900	28826393	ZWJ	1	Performed wet lab experiments|Interpretation of results	Interpretation of results	Analyzed the data	Formal analysis	YES
5563900	28826393	ZX	1	Conceived the idea|Interpretation of results	Conceived the idea	Conceived and designed the experiments	Conceptualization	YES
5563900	28826393	ZX	1	Conceived the idea|Interpretation of results	Interpretation of results	Analyzed the data	Formal analysis	YES
4412817	25919634	AE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412817	25919634	AE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412817	25919634	AE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412817	25919634	AE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412817	25919634	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412817	25919634	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412817	25919634	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412817	25919634	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412817	25919634	SSA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412817	25919634	SSA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412817	25919634	SSA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412817	25919634	SSA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3420321	22697405	All authors	2	were responsible for the development of the final experimental design	were responsible for the development of the final experimental design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3420321	22697405	CAH	2	were responsible for data analysis|were responsible for data collection|was responsible for reviewing drafts of the manuscript	were responsible for data analysis	Analyzed the data	Formal analysis	YES
3420321	22697405	CAH	2	were responsible for data analysis|were responsible for data collection|was responsible for reviewing drafts of the manuscript	were responsible for data collection	Performed the experiments	Investigation	YES
3420321	22697405	CAH	2	were responsible for data analysis|were responsible for data collection|was responsible for reviewing drafts of the manuscript	was responsible for reviewing drafts of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3420321	22697405	CS	2	were responsible for writing of the manuscript	were responsible for writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
3420321	22697405	JP	2	were responsible for data collection	were responsible for data collection	Performed the experiments	Investigation	YES
3420321	22697405	RCH	2	first proposed the study and undertook an initial pilot investigation|were responsible for writing of the manuscript|were responsible for data analysis	first proposed the study and undertook an initial pilot investigation	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
3420321	22697405	RCH	2	first proposed the study and undertook an initial pilot investigation|were responsible for writing of the manuscript|were responsible for data analysis	were responsible for writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
3420321	22697405	RCH	2	first proposed the study and undertook an initial pilot investigation|were responsible for writing of the manuscript|were responsible for data analysis	were responsible for data analysis	Analyzed the data	Formal analysis	YES
5634989	29019109	All authors	2	contributed to writing the manuscript	contributed to writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5634989	29019109	DB	2	contributed to analyzing the data	contributed to analyzing the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5634989	29019109	DPS	2	contributed to managing imaging procedures	contributed to managing imaging procedures	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
5634989	29019109	JC	2	contributed to managing imaging procedures	contributed to managing imaging procedures	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
5634989	29019109	MSH	2	contributed to designing the study|contributed to managing imaging procedures|contributed to analyzing the data	contributed to designing the study	Conceived and designed the experiments	Methodology	YES
5634989	29019109	MSH	2	contributed to designing the study|contributed to managing imaging procedures|contributed to analyzing the data	contributed to managing imaging procedures	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
5634989	29019109	MSH	2	contributed to designing the study|contributed to managing imaging procedures|contributed to analyzing the data	contributed to analyzing the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5634989	29019109	PYLR	2	contributed to designing the study|contributed to managing imaging procedures|contributed to analyzing the data	contributed to designing the study	Conceived and designed the experiments	Methodology	YES
5634989	29019109	PYLR	2	contributed to designing the study|contributed to managing imaging procedures|contributed to analyzing the data	contributed to managing imaging procedures	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
5634989	29019109	PYLR	2	contributed to designing the study|contributed to managing imaging procedures|contributed to analyzing the data	contributed to analyzing the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5634989	29019109	RJH	2	contributed to designing the study|contributed to managing imaging procedures|contributed to analyzing the data	contributed to designing the study	Conceived and designed the experiments	Methodology	YES
5634989	29019109	RJH	2	contributed to designing the study|contributed to managing imaging procedures|contributed to analyzing the data	contributed to managing imaging procedures	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
5634989	29019109	RJH	2	contributed to designing the study|contributed to managing imaging procedures|contributed to analyzing the data	contributed to analyzing the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5634989	29019109	SS	2	contributed to designing the study|contributed to managing imaging procedures	contributed to designing the study	Conceived and designed the experiments	Methodology	YES
5634989	29019109	SS	2	contributed to designing the study|contributed to managing imaging procedures	contributed to managing imaging procedures	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
5634989	29019109	YC	2	contributed to designing the study|contributed to analyzing the data	contributed to designing the study	Conceived and designed the experiments	Methodology	YES
5634989	29019109	YC	2	contributed to designing the study|contributed to analyzing the data	contributed to analyzing the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
1868958	17534430	AT	PLoS5	Was responsible for sample recruitment and assignment of clinical diagnoses	Was responsible for sample recruitment and assignment of clinical diagnoses	Performed the experiments	Investigation	YES
1868958	17534430	CB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Conceived the statistical methods|Programmed the statistical software for the analysis of the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1868958	17534430	CB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Conceived the statistical methods|Programmed the statistical software for the analysis of the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1868958	17534430	CB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Conceived the statistical methods|Programmed the statistical software for the analysis of the data	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1868958	17534430	CB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Conceived the statistical methods|Programmed the statistical software for the analysis of the data	Conceived the statistical methods	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
1868958	17534430	CB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Conceived the statistical methods|Programmed the statistical software for the analysis of the data	Programmed the statistical software for the analysis of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Software	YES
1868958	17534430	DC	PLoS5	Wrote the paper|Conceived the statistical methods	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1868958	17534430	DC	PLoS5	Wrote the paper|Conceived the statistical methods	Conceived the statistical methods	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
1868958	17534430	IP	PLoS5	Responsible for the data management	Responsible for the data management	Analyzed the data	Data curation	YES
1868958	17534430	LB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Conceived the statistical methods	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1868958	17534430	LB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Conceived the statistical methods	Analyzed the data	Analyzed the data	Formal analysis	YES
1868958	17534430	LB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Conceived the statistical methods	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1868958	17534430	LB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Conceived the statistical methods	Conceived the statistical methods	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
1868958	17534430	LF	PLoS5	Conceived and designed the experiments|Wrote the paper|Responsible for the data management	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1868958	17534430	LF	PLoS5	Conceived and designed the experiments|Wrote the paper|Responsible for the data management	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1868958	17534430	LF	PLoS5	Conceived and designed the experiments|Wrote the paper|Responsible for the data management	Responsible for the data management	Analyzed the data	Data curation	YES
1868958	17534430	LM	PLoS5	Was responsible for sample recruitment and assignment of clinical diagnoses	Was responsible for sample recruitment and assignment of clinical diagnoses	Performed the experiments	Investigation	YES
1868958	17534430	MP	PLoS5	Was responsible for sample recruitment and assignment of clinical diagnoses	Was responsible for sample recruitment and assignment of clinical diagnoses	Performed the experiments	Investigation	YES
1868958	17534430	PB	PLoS5	Performed the experiments|Was responsible for the biological bank	Performed the experiments	Performed the experiments	Investigation	YES
1868958	17534430	PB	PLoS5	Performed the experiments|Was responsible for the biological bank	Was responsible for the biological bank	-	-	NO
1868958	17534430	RF	PLoS5	Was responsible for sample recruitment and assignment of clinical diagnoses	Was responsible for sample recruitment and assignment of clinical diagnoses	Performed the experiments	Investigation	YES
1868958	17534430	RP	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1868958	17534430	SM	PLoS5	Was responsible for sample recruitment and assignment of clinical diagnoses	Was responsible for sample recruitment and assignment of clinical diagnoses	Performed the experiments	Investigation	YES
1868958	17534430	VS	PLoS5	Was responsible for sample recruitment and assignment of clinical diagnoses	Was responsible for sample recruitment and assignment of clinical diagnoses	Performed the experiments	Investigation	YES
3423002	22866974	AJY	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3423002	22866974	JCR	PLoS52	processed biological samples	processed biological samples	Analyzed the data	Data curation	YES
3423002	22866974	JPK	PLoS52	designed research|conducted research|conducted statistical analysis	designed research	Conceived and designed the experiments	Methodology	YES
3423002	22866974	JPK	PLoS52	designed research|conducted research|conducted statistical analysis	conducted research	Performed the experiments	Investigation	YES
3423002	22866974	JPK	PLoS52	designed research|conducted research|conducted statistical analysis	conducted statistical analysis	Analyzed the data	Formal analysis	YES
3423002	22866974	JPM	PLoS52	designed research|conducted research|wrote the paper|had primary responsibility for final content	designed research	Conceived and designed the experiments	Methodology	YES
3423002	22866974	JPM	PLoS52	designed research|conducted research|wrote the paper|had primary responsibility for final content	conducted research	Performed the experiments	Investigation	YES
3423002	22866974	JPM	PLoS52	designed research|conducted research|wrote the paper|had primary responsibility for final content	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3423002	22866974	JPM	PLoS52	designed research|conducted research|wrote the paper|had primary responsibility for final content	had primary responsibility for final content	-	-	NO
3423002	22866974	KWW	PLoS52	conducted research	conducted research	Performed the experiments	Investigation	YES
3423002	22866974	LJL	PLoS52	conducted statistical analysis|wrote the paper	conducted statistical analysis	Analyzed the data	Formal analysis	YES
3423002	22866974	LJL	PLoS52	conducted statistical analysis|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3423002	22866974	SJC	PLoS52	conducted research	conducted research	Performed the experiments	Investigation	YES
5702509	29209348	RW	2	planned and designed the research	planned and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5702509	29209348	XP	2	planned and designed the research|wrote the manuscript	planned and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5702509	29209348	XP	2	planned and designed the research|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5702509	29209348	YZ	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5702509	29209348	ZW	2	planned and designed the research|wrote the manuscript	planned and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5702509	29209348	ZW	2	planned and designed the research|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4412818	25919398	SS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412818	25919398	SS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412818	25919398	SS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412818	25919398	WHT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412818	25919398	WHT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412818	25919398	WHT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412818	25919398	WHT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412818	25919398	WHT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5636775	29022216	AHS	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5636775	29022216	HI	PLoS52	conducted the pet experiment|analyzed the data	conducted the pet experiment	Performed the experiments	Investigation	YES
5636775	29022216	HI	PLoS52	conducted the pet experiment|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5636775	29022216	KY	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5636775	29022216	MO	PLoS52	conducted the pet experiment	conducted the pet experiment	Performed the experiments	Investigation	YES
5636775	29022216	NM	PLoS52	mainly revised the manuscript	mainly revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5636775	29022216	TA	PLoS52	conducted the pet experiment	conducted the pet experiment	Performed the experiments	Investigation	YES
5636775	29022216	TI	PLoS52	mainly revised the manuscript	mainly revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5636775	29022216	TK	PLoS52	designed the study and wrote the protocol|wrote the first draft of the manuscript	designed the study and wrote the protocol	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5636775	29022216	TK	PLoS52	designed the study and wrote the protocol|wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
5567635	28830347	ABG	PLoS52	provided training, consultation, and critical help with the bioinformatics data analysis	provided training, consultation, and critical help with the bioinformatics data analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5567635	28830347	AM	PLoS52	designed the research|performed the research and analyzed data|wrote the paper	designed the research	Conceived and designed the experiments	Methodology	YES
5567635	28830347	AM	PLoS52	designed the research|performed the research and analyzed data|wrote the paper	performed the research and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5567635	28830347	AM	PLoS52	designed the research|performed the research and analyzed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5567635	28830347	All authors	PLoS52	edited and/or approved the paper	edited and/or approved the paper	Wrote the paper	Writing - Review & Editing	YES
5567635	28830347	KDC	PLoS52	performed the research and analyzed data|wrote the paper	performed the research and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5567635	28830347	KDC	PLoS52	performed the research and analyzed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5567635	28830347	LM	PLoS52	provided training, consultation, and critical help with the bioinformatics data analysis	provided training, consultation, and critical help with the bioinformatics data analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5567635	28830347	NFP	PLoS52	provided training, consultation, and critical help with the bioinformatics data analysis	provided training, consultation, and critical help with the bioinformatics data analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
1868959	17534427	AC	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1868959	17534427	AC	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1868959	17534427	GW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1868959	17534427	KB	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1868959	17534427	KM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1868959	17534427	KM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1868959	17534427	KM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1868959	17534427	KM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1868959	17534427	MH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1868959	17534427	MW	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1868959	17534427	OK	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1868959	17534427	OK	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1868959	17534427	QC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1868959	17534427	QC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1868959	17534427	QC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1868959	17534427	SN	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1868959	17534427	UR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1868959	17534427	UR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1868959	17534427	UR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1868959	17534427	WP	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
3423013	22835267	DAponte	2	participated to the acquisition of data and carried out the wingate test	participated to the acquisition of data and carried out the wingate test	Performed the experiments	Investigation	YES
3423013	22835267	Francesco Mario Limongelli	2	have given final approval of the version	have given final approval of the version	-	-	NO
3423013	22835267	Luca Rastrelli	2	performed the water analysis, participated the interpretation of data, drafted the manuscript and given final approval of the version	performed the water analysis, participated the interpretation of data, drafted the manuscript and given final approval of the version	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3423013	22835267	Paola Brancaccio	2	participated the design of the study, performed the statistical analysis, the interpretation of data and drafted the manuscript	participated the design of the study, performed the statistical analysis, the interpretation of data and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3423013	22835267	Vincenzo Donnarumma	2	carried out all the laboratory analysis	carried out all the laboratory analysis	Performed the experiments	Investigation	YES
5643834	29038960	All authors	2	made substantial contribution to the conception of this commentary, have been involved in drafting, given final approval of the version to be published, and agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	made substantial contribution to the conception of this commentary, have been involved in drafting, given final approval of the version to be published, and agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4600926	26491657	Adane Worku	2	was involved in the spoligotyping of the isolates and interpretation	was involved in the spoligotyping of the isolates and interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4600926	26491657	Anwar Nuru	2	was involved in the design, data collection and laboratory work, and statistical analysis and interpretation of data and drafted the paper	was involved in the design, data collection and laboratory work, and statistical analysis and interpretation of data and drafted the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4600926	26491657	Gezahegne Mamo	2	was involved in the design, interpretation, and critical revision of the paper	was involved in the design, interpretation, and critical revision of the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4600926	26491657	Girmay Medhin	2	was involved in the design, statistical analysis, and critical revision of the paper	was involved in the design, statistical analysis, and critical revision of the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4600926	26491657	Gobena Ameni	2	was involved in the design, interpretation, and critical revision of the paper	was involved in the design, interpretation, and critical revision of the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4600926	26491657	Rembert Pieper	2	was involved in critical revision of the paper	was involved in critical revision of the paper	Wrote the paper	Writing - Review & Editing	YES
4600926	26491657	TB	2	culture, and interpretation	culture, and interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4412819	25918849	BG	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412819	25918849	BG	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412819	25918849	IB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412819	25918849	IB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412819	25918849	IB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412819	25918849	IB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412819	25918849	JMB	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412819	25918849	JMB	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412819	25918849	KS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412819	25918849	KS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412819	25918849	LJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412819	25918849	LJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412819	25918849	LJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412819	25918849	LJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412819	25918849	SP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412819	25918849	SP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412819	25918849	SP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412819	25918849	SP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412819	25918849	TO	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412819	25918849	TO	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412819	25918849	TO	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412819	25918849	TO	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4536250	26272478	AH	2	have designed the work|carried out the experiment|analyzed the data and contributed for the statistical analysis|wrote the manuscript and reviewed the manuscript critically	have designed the work	Conceived and designed the experiments	-	YES
4536250	26272478	AH	2	have designed the work|carried out the experiment|analyzed the data and contributed for the statistical analysis|wrote the manuscript and reviewed the manuscript critically	carried out the experiment	Performed the experiments	Investigation	YES
4536250	26272478	AH	2	have designed the work|carried out the experiment|analyzed the data and contributed for the statistical analysis|wrote the manuscript and reviewed the manuscript critically	analyzed the data and contributed for the statistical analysis	Analyzed the data	Formal analysis	YES
4536250	26272478	AH	2	have designed the work|carried out the experiment|analyzed the data and contributed for the statistical analysis|wrote the manuscript and reviewed the manuscript critically	wrote the manuscript and reviewed the manuscript critically	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4536250	26272478	All authors	2	read the article and approved the final manuscript	read the article and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4536250	26272478	MFL	2	have designed the work|analyzed the data and contributed for the statistical analysis|wrote the manuscript and reviewed the manuscript critically	have designed the work	Conceived and designed the experiments	-	YES
4536250	26272478	MFL	2	have designed the work|analyzed the data and contributed for the statistical analysis|wrote the manuscript and reviewed the manuscript critically	analyzed the data and contributed for the statistical analysis	Analyzed the data	Formal analysis	YES
4536250	26272478	MFL	2	have designed the work|analyzed the data and contributed for the statistical analysis|wrote the manuscript and reviewed the manuscript critically	wrote the manuscript and reviewed the manuscript critically	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4536250	26272478	MK	2	have designed the work|analyzed the data and contributed for the statistical analysis|wrote the manuscript and reviewed the manuscript critically	have designed the work	Conceived and designed the experiments	-	YES
4536250	26272478	MK	2	have designed the work|analyzed the data and contributed for the statistical analysis|wrote the manuscript and reviewed the manuscript critically	analyzed the data and contributed for the statistical analysis	Analyzed the data	Formal analysis	YES
4536250	26272478	MK	2	have designed the work|analyzed the data and contributed for the statistical analysis|wrote the manuscript and reviewed the manuscript critically	wrote the manuscript and reviewed the manuscript critically	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4536250	26272478	NY	2	carried out the experiment	carried out the experiment	Performed the experiments	Investigation	YES
4536250	26272478	PGYSYS	2	jacobs university bremen	jacobs university bremen	-	-	NO
1868965	17534432	AE	PLoS5	Conceived and designed the experiments|Analyzed the data|Patient enrollment	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1868965	17534432	AE	PLoS5	Conceived and designed the experiments|Analyzed the data|Patient enrollment	Analyzed the data	Analyzed the data	Formal analysis	YES
1868965	17534432	AE	PLoS5	Conceived and designed the experiments|Analyzed the data|Patient enrollment	Patient enrollment	Performed the experiments	Investigation	YES
1868965	17534432	AP	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1868965	17534432	AP	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1868965	17534432	CB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1868965	17534432	GC	PLoS5	Conceived and designed the experiments|Analyzed the data|Patient enrollment	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1868965	17534432	GC	PLoS5	Conceived and designed the experiments|Analyzed the data|Patient enrollment	Analyzed the data	Analyzed the data	Formal analysis	YES
1868965	17534432	GC	PLoS5	Conceived and designed the experiments|Analyzed the data|Patient enrollment	Patient enrollment	Performed the experiments	Investigation	YES
1868965	17534432	JC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1868965	17534432	JD	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1868965	17534432	MG	PLoS5	Performed the experiments|Histological evaluation	Performed the experiments	Performed the experiments	Investigation	YES
1868965	17534432	MG	PLoS5	Performed the experiments|Histological evaluation	Histological evaluation	Performed the experiments	Investigation	YES
1868965	17534432	MM	PLoS5	Analyzed the data|Patient enrollment	Analyzed the data	Analyzed the data	Formal analysis	YES
1868965	17534432	MM	PLoS5	Analyzed the data|Patient enrollment	Patient enrollment	Performed the experiments	Investigation	YES
1868965	17534432	MN	PLoS5	Conceived and designed the experiments|Analyzed the data|Patient enrollment	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1868965	17534432	MN	PLoS5	Conceived and designed the experiments|Analyzed the data|Patient enrollment	Analyzed the data	Analyzed the data	Formal analysis	YES
1868965	17534432	MN	PLoS5	Conceived and designed the experiments|Analyzed the data|Patient enrollment	Patient enrollment	Performed the experiments	Investigation	YES
1868965	17534432	MS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1868965	17534432	MS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1868965	17534432	MS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1868965	17534432	NK	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1868965	17534432	NK	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1868965	17534432	RP	PLoS5	Analyzed the data|Statistical analysis	Analyzed the data	Analyzed the data	Formal analysis	YES
1868965	17534432	RP	PLoS5	Analyzed the data|Statistical analysis	Statistical analysis	Analyzed the data	Formal analysis	YES
1868965	17534432	TK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1868965	17534432	TK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1868965	17534432	TK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1868965	17534432	TR	PLoS5	Analyzed the data|Statistical analysis	Analyzed the data	Analyzed the data	Formal analysis	YES
1868965	17534432	TR	PLoS5	Analyzed the data|Statistical analysis	Statistical analysis	Analyzed the data	Formal analysis	YES
3428650	22574901	BSG	2	contributed to the coordination and helped draft the manuscript	contributed to the coordination and helped draft the manuscript	Wrote the paper	Project administration|Writing - Original Draft	YES
3428650	22574901	ELO	2	contributed to study design, data collection and manuscript preparation	contributed to study design, data collection and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Methodology|Resources|Writing - Original Draft	YES
3428650	22574901	FJLG	2	served as the principal investigators and contributed to study design, data collection, and manuscript preparation	served as the principal investigators and contributed to study design, data collection, and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Funding acquisition|Investigation|Methodology|Resources|Writing - Original Draft	YES
3428650	22574901	JCLA	2	contributed to study design, data collection and manuscript preparation	contributed to study design, data collection and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Methodology|Resources|Writing - Original Draft	YES
3428650	22574901	JGGG	2	contributed to data collection and manuscript preparation	contributed to data collection and manuscript preparation	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3428650	22574901	JZVP	2	contributed to the coordination and helped draft the manuscript	contributed to the coordination and helped draft the manuscript	Wrote the paper	Project administration|Writing - Original Draft	YES
3428650	22574901	LEMG	2	contributed to study design, data collection and manuscript preparation	contributed to study design, data collection and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Methodology|Resources|Writing - Original Draft	YES
3428650	22574901	LGMA	2	participated in statistical analysis and manuscript preparation	participated in statistical analysis and manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3428650	22574901	MRTS	2	contributed to de acylcarnitine measures, participated in statistical analysis and manuscript preparation	contributed to de acylcarnitine measures, participated in statistical analysis and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3428650	22574901	RRG	2	served as the principal investigators and contributed to study design, data collection, and manuscript preparation	served as the principal investigators and contributed to study design, data collection, and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Funding acquisition|Investigation|Methodology|Resources|Writing - Original Draft	YES
5567642	28830353	BC	2	collected the samples	collected the samples	Performed the experiments	Investigation	YES
5567642	28830353	CMT	2	conceived and designed the project	conceived and designed the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5567642	28830353	SQT	2	performed the experiments and drafted the manuscript	performed the experiments and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5567642	28830353	YML	2	conceived and designed the project|revised the manuscript	conceived and designed the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5567642	28830353	YML	2	conceived and designed the project|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
3830889	24288480	Bo Liu	2	contributed equally to this work	contributed equally to this work	-	-	NO
3830889	24288480	Xin Gong	2	contributed equally to this work	contributed equally to this work	-	-	NO
5702872	29213277	GL	7	Collected the x-ray data	Collected the x-ray data	Performed the experiments	Investigation	YES
5702872	29213277	HZ	7	Collected the x-ray data	Collected the x-ray data	Performed the experiments	Investigation	YES
5702872	29213277	JC	7	Designed the experiments|Analyzed the data|Solved the structure|Wrote the manuscript	Designed the experiments	Conceived and designed the experiments	Methodology	YES
5702872	29213277	JC	7	Designed the experiments|Analyzed the data|Solved the structure|Wrote the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
5702872	29213277	JC	7	Designed the experiments|Analyzed the data|Solved the structure|Wrote the manuscript	Solved the structure	-	-	NO
5702872	29213277	JC	7	Designed the experiments|Analyzed the data|Solved the structure|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5702872	29213277	SL	7	Designed the experiments|Performed the experiments|Analyzed the data|Edited the figures	Designed the experiments	Conceived and designed the experiments	Methodology	YES
5702872	29213277	SL	7	Designed the experiments|Performed the experiments|Analyzed the data|Edited the figures	Performed the experiments	Performed the experiments	Investigation	YES
5702872	29213277	SL	7	Designed the experiments|Performed the experiments|Analyzed the data|Edited the figures	Analyzed the data	Analyzed the data	Formal analysis	YES
5702872	29213277	SL	7	Designed the experiments|Performed the experiments|Analyzed the data|Edited the figures	Edited the figures	Wrote the paper	Visualization|Writing - Review & Editing	YES
5702872	29213277	WS	7	Designed the experiments|Performed the experiments|Analyzed the data|Wrote the manuscript	Designed the experiments	Conceived and designed the experiments	Methodology	YES
5702872	29213277	WS	7	Designed the experiments|Performed the experiments|Analyzed the data|Wrote the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
5702872	29213277	WS	7	Designed the experiments|Performed the experiments|Analyzed the data|Wrote the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
5702872	29213277	WS	7	Designed the experiments|Performed the experiments|Analyzed the data|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5702872	29213277	ZH	7	Designed the experiments|Analyzed the data|Wrote the manuscript	Designed the experiments	Conceived and designed the experiments	Methodology	YES
5702872	29213277	ZH	7	Designed the experiments|Analyzed the data|Wrote the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
5702872	29213277	ZH	7	Designed the experiments|Analyzed the data|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5702872	29213277	ZW	7	Designed the experiments|Performed the experiments|Analyzed the data|Edited the figures|Wrote the manuscript	Designed the experiments	Conceived and designed the experiments	Methodology	YES
5702872	29213277	ZW	7	Designed the experiments|Performed the experiments|Analyzed the data|Edited the figures|Wrote the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
5702872	29213277	ZW	7	Designed the experiments|Performed the experiments|Analyzed the data|Edited the figures|Wrote the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
5702872	29213277	ZW	7	Designed the experiments|Performed the experiments|Analyzed the data|Edited the figures|Wrote the manuscript	Edited the figures	Wrote the paper	Visualization|Writing - Review & Editing	YES
5702872	29213277	ZW	7	Designed the experiments|Performed the experiments|Analyzed the data|Edited the figures|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
1871610	17534440	DZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1871610	17534440	DZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1871610	17534440	DZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1871610	17534440	DZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1871610	17534440	DZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1871610	17534440	GH	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1871610	17534440	GH	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1871610	17534440	JC	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1871610	17534440	JC	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1871610	17534440	JL	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1871610	17534440	JX	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1871610	17534440	JX	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1871610	17534440	JX	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1871610	17534440	KW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1871610	17534440	KW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1871610	17534440	KW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1871610	17534440	PM	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1871610	17534440	PM	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4412821	25919024	CFY	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412821	25919024	MJJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412821	25919024	MJJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412821	25919024	MJJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412821	25919024	MJJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412821	25919024	MJJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412821	25919024	PCT	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412821	25919024	WJS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412821	25919024	YSL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412821	25919024	YSL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5954879	29854721	Elisa B. Vandervort	2	contributed to the cervical cancer prevention literature review, discussion, critical review, and editing of the manuscript	contributed to the cervical cancer prevention literature review, discussion, critical review, and editing of the manuscript	Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5954879	29854721	Fabiola V. Moshi	2	drafted the manuscript and led the process of critical revision of the manuscript	drafted the manuscript and led the process of critical revision of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5954879	29854721	Stephen M. Kibusi	2	developed the study framework and study design, performed the statistical analysis, drafted the methods section of the paper, and participated in critical revision of the manuscript	developed the study framework and study design, performed the statistical analysis, drafted the methods section of the paper, and participated in critical revision of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5567656	28830358	DG	CRediT	coded it	coded it	-	-	NO
5567656	28830358	DR	CRediT	coded it	coded it	-	-	NO
5651532	29058157	BH	2	were involved in the planning of this study and supervision	were involved in the planning of this study and supervision	Conceived and designed the experiments	Methodology|Supervision	YES
5651532	29058157	FH	2	developed the algorithm used in the rover software used for measurement and supervised all technical aspects of the study regarding the rover software and its algorithm	developed the algorithm used in the rover software used for measurement and supervised all technical aspects of the study regarding the rover software and its algorithm	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software|Supervision	YES
5651532	29058157	GD	2	were involved in the planning of this study and supervision	were involved in the planning of this study and supervision	Conceived and designed the experiments	Methodology|Supervision	YES
5651532	29058157	JCJ	2	screened the database and collected the population eligible for measurement	screened the database and collected the population eligible for measurement	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5651532	29058157	MRM	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5651532	29058157	SM	2	screened the database and collected the population eligible for measurement|performed the measurement, analyzed the data, and wrote the manuscript	screened the database and collected the population eligible for measurement	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5651532	29058157	SM	2	screened the database and collected the population eligible for measurement|performed the measurement, analyzed the data, and wrote the manuscript	performed the measurement, analyzed the data, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5651532	29058157	The authors	2	were involved in the planning of this study and supervision	were involved in the planning of this study and supervision	Conceived and designed the experiments	Methodology|Supervision	YES
5651532	29058157	VP	2	were involved in the planning of this study and supervision	were involved in the planning of this study and supervision	Conceived and designed the experiments	Methodology|Supervision	YES
5651532	29058157	WB	2	were involved in the planning of this study and supervision	were involved in the planning of this study and supervision	Conceived and designed the experiments	Methodology|Supervision	YES
3439332	22691230	Benedito Pereira	2	were responsible for the supplementation program/procedure and acquisition of anaerobic performance data during the wingate test	were responsible for the supplementation program/procedure and acquisition of anaerobic performance data during the wingate test	Performed the experiments	Investigation	YES
3439332	22691230	Chrislaine O. Soares	2	were involved in hplc analyses for lipid oxidation data	were involved in hplc analyses for lipid oxidation data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3439332	22691230	Douglas Ganini	2	were involved in hplc analyses for lipid oxidation data	were involved in hplc analyses for lipid oxidation data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3439332	22691230	Leandro Lorenco-Lima	2	were responsible for the supplementation program/procedure and acquisition of anaerobic performance data during the wingate test	were responsible for the supplementation program/procedure and acquisition of anaerobic performance data during the wingate test	Performed the experiments	Investigation	YES
3439332	22691230	Leonardo R. Silveira	2	substantially contributed to the improvement of our physiological approach of our hypothesis	substantially contributed to the improvement of our physiological approach of our hypothesis	-	-	NO
3439332	22691230	M.Sc	2	were responsible for the supplementation program/procedure and acquisition of anaerobic performance data during the wingate test	were responsible for the supplementation program/procedure and acquisition of anaerobic performance data during the wingate test	Performed the experiments	Investigation	YES
3439332	22691230	MS	2	in order to improve the quality of our contribution	in order to improve the quality of our contribution	-	-	NO
3439332	22691230	Rui Curi	2	substantially contributed to the improvement of our physiological approach of our hypothesis	substantially contributed to the improvement of our physiological approach of our hypothesis	-	-	NO
1871611	17534425	EP	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1871611	17534425	EP	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1871611	17534425	EP	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1871611	17534425	EP	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1871611	17534425	FC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1871611	17534425	FC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1871611	17534425	FC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1871611	17534425	FC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1871611	17534425	FC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1871611	17534425	LB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1871611	17534425	LB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1871611	17534425	LB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1871611	17534425	LM	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1871611	17534425	LM	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1871611	17534425	NB	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1871611	17534425	NB	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1871611	17534425	SL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1871611	17534425	SL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1871611	17534425	SL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1871611	17534425	SL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4603312	26491689	Chuankui Wei	PLoS52	contributed to the study design and conducted data collection|conducted data analysis and interpretation of results|wrote the paper	contributed to the study design and conducted data collection	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources	YES
4603312	26491689	Chuankui Wei	PLoS52	contributed to the study design and conducted data collection|conducted data analysis and interpretation of results|wrote the paper	conducted data analysis and interpretation of results	Analyzed the data	Formal analysis	YES
4603312	26491689	Chuankui Wei	PLoS52	contributed to the study design and conducted data collection|conducted data analysis and interpretation of results|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4603312	26491689	Dengfeng Li	PLoS52	conducted data analysis and interpretation of results	conducted data analysis and interpretation of results	Analyzed the data	Formal analysis	YES
4603312	26491689	Hongming Song	PLoS52	contributed to the study design and conducted data collection|conducted data analysis and interpretation of results|wrote the paper	contributed to the study design and conducted data collection	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources	YES
4603312	26491689	Hongming Song	PLoS52	contributed to the study design and conducted data collection|conducted data analysis and interpretation of results|wrote the paper	conducted data analysis and interpretation of results	Analyzed the data	Formal analysis	YES
4603312	26491689	Hongming Song	PLoS52	contributed to the study design and conducted data collection|conducted data analysis and interpretation of results|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4603312	26491689	Jialu Song	PLoS52	conducted data analysis and interpretation of results	conducted data analysis and interpretation of results	Analyzed the data	Formal analysis	YES
4603312	26491689	Kaiyao Hua	PLoS52	conducted data analysis and interpretation of results	conducted data analysis and interpretation of results	Analyzed the data	Formal analysis	YES
4603312	26491689	Lin Fang	PLoS52	contributed to the study design and conducted data collection|conducted data analysis and interpretation of results	contributed to the study design and conducted data collection	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources	YES
4603312	26491689	Lin Fang	PLoS52	contributed to the study design and conducted data collection|conducted data analysis and interpretation of results	conducted data analysis and interpretation of results	Analyzed the data	Formal analysis	YES
4603312	26491689	Niraj Maskey	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412822	25918839	AMB	PLoS5	Performed the experiments|Analyzed the data|Read and approved the final manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4412822	25918839	AMB	PLoS5	Performed the experiments|Analyzed the data|Read and approved the final manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4412822	25918839	AMB	PLoS5	Performed the experiments|Analyzed the data|Read and approved the final manuscript	Read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4412822	25918839	EBZ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Designed the experiments|Read and approved the final manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4412822	25918839	EBZ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Designed the experiments|Read and approved the final manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4412822	25918839	EBZ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Designed the experiments|Read and approved the final manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412822	25918839	EBZ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Designed the experiments|Read and approved the final manuscript	Designed the experiments	Conceived and designed the experiments	Methodology	YES
4412822	25918839	EBZ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Designed the experiments|Read and approved the final manuscript	Read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4412822	25918839	KS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Designed the experiments|Read and approved the final manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4412822	25918839	KS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Designed the experiments|Read and approved the final manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4412822	25918839	KS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Designed the experiments|Read and approved the final manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412822	25918839	KS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Designed the experiments|Read and approved the final manuscript	Designed the experiments	Conceived and designed the experiments	Methodology	YES
4412822	25918839	KS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Designed the experiments|Read and approved the final manuscript	Read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4412822	25918839	MAL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Conceived the study|Designed the experiments|Read and approved the final manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4412822	25918839	MAL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Conceived the study|Designed the experiments|Read and approved the final manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4412822	25918839	MAL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Conceived the study|Designed the experiments|Read and approved the final manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412822	25918839	MAL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Conceived the study|Designed the experiments|Read and approved the final manuscript	Conceived the study	Conceived and designed the experiments	Conceptualization	YES
4412822	25918839	MAL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Conceived the study|Designed the experiments|Read and approved the final manuscript	Designed the experiments	Conceived and designed the experiments	Methodology	YES
4412822	25918839	MAL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Conceived the study|Designed the experiments|Read and approved the final manuscript	Read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4412822	25918839	MPD	PLoS5	Conceived the study|Read and approved the final manuscript	Conceived the study	Conceived and designed the experiments	Conceptualization	YES
4412822	25918839	MPD	PLoS5	Conceived the study|Read and approved the final manuscript	Read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4412822	25918839	PDF	PLoS5	Conceived the study|Read and approved the final manuscript	Conceived the study	Conceived and designed the experiments	Conceptualization	YES
4412822	25918839	PDF	PLoS5	Conceived the study|Read and approved the final manuscript	Read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4412822	25918839	SCF	PLoS5	Contributed reagents/materials/analysis tools|Conceived the study|Read and approved the final manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412822	25918839	SCF	PLoS5	Contributed reagents/materials/analysis tools|Conceived the study|Read and approved the final manuscript	Conceived the study	Conceived and designed the experiments	Conceptualization	YES
4412822	25918839	SCF	PLoS5	Contributed reagents/materials/analysis tools|Conceived the study|Read and approved the final manuscript	Read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4412822	25918839	SHH	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper|Conceived the study|Read and approved the final manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412822	25918839	SHH	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper|Conceived the study|Read and approved the final manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412822	25918839	SHH	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper|Conceived the study|Read and approved the final manuscript	Conceived the study	Conceived and designed the experiments	Conceptualization	YES
4412822	25918839	SHH	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper|Conceived the study|Read and approved the final manuscript	Read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4412822	25918839	UN	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Designed the experiments|Read and approved the final manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4412822	25918839	UN	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Designed the experiments|Read and approved the final manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4412822	25918839	UN	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Designed the experiments|Read and approved the final manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412822	25918839	UN	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Designed the experiments|Read and approved the final manuscript	Designed the experiments	Conceived and designed the experiments	Methodology	YES
4412822	25918839	UN	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Designed the experiments|Read and approved the final manuscript	Read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5702907	29213276	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5702907	29213276	BC	2	were involved in the preparation of samples	were involved in the preparation of samples	Performed the experiments	Investigation	YES
5702907	29213276	BG	2	provided help with cytological observations	provided help with cytological observations	Performed the experiments	Investigation	YES
5702907	29213276	BV	2	gathered the proteomic data	gathered the proteomic data	Performed the experiments	Investigation	YES
5702907	29213276	DH	2	designed and performed the experimental work	designed and performed the experimental work	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5702907	29213276	GC	2	were involved in the preparation of samples	were involved in the preparation of samples	Performed the experiments	Investigation	YES
5702907	29213276	GCl	2	completed the metabolome analyses	completed the metabolome analyses	Analyzed the data	Formal analysis	YES
5702907	29213276	HM	2	provided help with cytological observations	provided help with cytological observations	Performed the experiments	Investigation	YES
5702907	29213276	IL	2	designed and performed the experimental work	designed and performed the experimental work	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5702907	29213276	LR	2	designed and performed the experimental work|wrote the manuscript	designed and performed the experimental work	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5702907	29213276	LR	2	designed and performed the experimental work|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5702907	29213276	MG	2	designed and performed the experimental work|wrote the manuscript	designed and performed the experimental work	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5702907	29213276	MG	2	designed and performed the experimental work|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5702907	29213276	The authors	2	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	Performed the experiments	Investigation	YES
3441280	22510240	AB	2	participated in the design and conception of the study and helped to draft the manuscript	participated in the design and conception of the study and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
3441280	22510240	EJCMC	2	carried out the human intervention study, participated in the data analysis and drafted the manuscript	carried out the human intervention study, participated in the data analysis and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3441280	22510240	ICWA	2	participated in the design and data analysis of the study, and drafted the manuscript	participated in the design and data analysis of the study, and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3441280	22510240	MACH	2	participated in the design of the study and helped to draft the manuscript	participated in the design of the study and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3441280	22510240	MJLB	2	participated in the design of the study and helped to draft the manuscript	participated in the design of the study and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3441280	22510240	NH	2	produced the pellets and carried out the dissolution experiments	produced the pellets and carried out the dissolution experiments	Performed the experiments	Investigation	YES
3441280	22510240	PCD	2	conceived of the study, participated in the design and coordination of the study, and helped to draft the manuscript	conceived of the study, participated in the design and coordination of the study, and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
4542858	26289773	Both authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4542858	26289773	DIM	PLoS52	conceived the project and obtained the financial support|wrote the paper	conceived the project and obtained the financial support	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
4542858	26289773	DIM	PLoS52	conceived the project and obtained the financial support|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4542858	26289773	NMCS	PLoS52	performed the experimental study|wrote the paper	performed the experimental study	Performed the experiments	Investigation	YES
4542858	26289773	NMCS	PLoS52	performed the experimental study|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6011085	29977904	All authors	PLoS52	revised, read, and approved the final draft for submission	revised, read, and approved the final draft for submission	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6011085	29977904	Bright Addo	PLoS52	conceived the design of the study|did the literature review and drafted the manuscript	conceived the design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6011085	29977904	Bright Addo	PLoS52	conceived the design of the study|did the literature review and drafted the manuscript	did the literature review and drafted the manuscript	Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
6011085	29977904	N. K. Babayara	PLoS52	analysed the data|reviewed and edited the draft manuscript	analysed the data	Analyzed the data	Formal analysis	YES
6011085	29977904	N. K. Babayara	PLoS52	analysed the data|reviewed and edited the draft manuscript	reviewed and edited the draft manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6011085	29977904	Sally Sencherey	PLoS52	conceived the design of the study|collected the data|did the literature review and drafted the manuscript	conceived the design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6011085	29977904	Sally Sencherey	PLoS52	conceived the design of the study|collected the data|did the literature review and drafted the manuscript	collected the data	Performed the experiments	Investigation	YES
6011085	29977904	Sally Sencherey	PLoS52	conceived the design of the study|collected the data|did the literature review and drafted the manuscript	did the literature review and drafted the manuscript	Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5567664	28830357	CG	PLoS52	designed and coordinated the projects, evaluated the data and wrote the article	designed and coordinated the projects, evaluated the data and wrote the article	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft	YES
5567664	28830357	EMS	PLoS52	carried out experiments, collected and analysed the data	carried out experiments, collected and analysed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5567664	28830357	ER	PLoS52	analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
5567664	28830357	ET	PLoS52	designed and coordinated the projects	designed and coordinated the projects	Conceived and designed the experiments	Methodology|Project administration	YES
5567664	28830357	H-RH	PLoS52	provided plant material and phenotypic evaluations	provided plant material and phenotypic evaluations	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5567664	28830357	JD	PLoS52	analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
5567664	28830357	JL	PLoS52	designed and coordinated the projects	designed and coordinated the projects	Conceived and designed the experiments	Methodology|Project administration	YES
5567664	28830357	JMP	PLoS52	analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
5567664	28830357	JS	PLoS52	provided plant material and phenotypic evaluations	provided plant material and phenotypic evaluations	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5567664	28830357	NC	PLoS52	carried out experiments, collected and analysed the data	carried out experiments, collected and analysed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5655379	29067565	All authors	2	contributed to the manuscript	contributed to the manuscript	-	-	NO
5655379	29067565	GEDM	2	devised and managed the project and revised the manuscript	devised and managed the project and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Project administration|Writing - Review & Editing	YES
5655379	29067565	JKB	2	performed the quantitative image analysis of the pet data	performed the quantitative image analysis of the pet data	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
5655379	29067565	JRB	2	devised and managed the project and revised the manuscript	devised and managed the project and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Project administration|Writing - Review & Editing	YES
5655379	29067565	KS	2	performed the quantitative image analysis of the pet data	performed the quantitative image analysis of the pet data	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
5655379	29067565	PJB	2	devised and managed the project and revised the manuscript	devised and managed the project and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Project administration|Writing - Review & Editing	YES
5655379	29067565	SN	2	carried out the experiments and prepared the first draft of the manuscript	carried out the experiments and prepared the first draft of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4603314	26491663	Elias Chelala	2	had similar contributions to this paper	had similar contributions to this paper	-	-	NO
4603314	26491663	Hala El Rami	2	had similar contributions to this paper	had similar contributions to this paper	-	-	NO
1871612	17534438	AH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1871612	17534438	AH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1871612	17534438	AH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1871612	17534438	AH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1871612	17534438	AR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1871612	17534438	AR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1871612	17534438	AR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1871612	17534438	AS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1871612	17534438	AS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1871612	17534438	ES	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
3441850	22853297	CT	2	aided with data collection and analysis	aided with data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3441850	22853297	DM	2	conceived the study and participated in its design	conceived the study and participated in its design	Conceived and designed the experiments	Conceptualization|Methodology	YES
3441850	22853297	DP	2	aided with data collection and analysis	aided with data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3441850	22853297	JB	2	aided with data collection and analysis	aided with data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3441850	22853297	JS	2	was the principle investigator of the study|conceived the study and participated in its design|were responsible for the biochemical measurement and analysis	was the principle investigator of the study	-	-	NO
3441850	22853297	JS	2	was the principle investigator of the study|conceived the study and participated in its design|were responsible for the biochemical measurement and analysis	conceived the study and participated in its design	Conceived and designed the experiments	Conceptualization|Methodology	YES
3441850	22853297	JS	2	was the principle investigator of the study|conceived the study and participated in its design|were responsible for the biochemical measurement and analysis	were responsible for the biochemical measurement and analysis	Performed the experiments	Investigation	YES
3441850	22853297	KH	2	aided with data collection and analysis	aided with data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3441850	22853297	RV	2	conceived the study and participated in its design|were responsible for the biochemical measurement and analysis	conceived the study and participated in its design	Conceived and designed the experiments	Conceptualization|Methodology	YES
3441850	22853297	RV	2	conceived the study and participated in its design|were responsible for the biochemical measurement and analysis	were responsible for the biochemical measurement and analysis	Performed the experiments	Investigation	YES
3441850	22853297	SA	2	conceived the study and participated in its design	conceived the study and participated in its design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5703732	29218056	CQ	2	conceived and coordinated the study and finalized the article	conceived and coordinated the study and finalized the article	Conceived and designed the experiments|Wrote the paper	Conceptualization|Project administration|Writing - Review & Editing	YES
5703732	29218056	JM	2	isolated and cloned the pvrboha gene, made the rnai construct, conceived the study, and contributed in drafting manuscript	isolated and cloned the pvrboha gene, made the rnai construct, conceived the study, and contributed in drafting manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
5703732	29218056	LC	2	critically evaluated the data	critically evaluated the data	-	-	NO
5703732	29218056	M-KA	2	conducted the experiments, analyzed the data, and wrote the article	conducted the experiments, analyzed the data, and wrote the article	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5703732	29218056	NN	2	generated transgenic hairy roots and assisted in inoculation experiments with rhizobia	generated transgenic hairy roots and assisted in inoculation experiments with rhizobia	Performed the experiments	Investigation	YES
5703732	29218056	RS-L	2	assisted with histology and microscopy	assisted with histology and microscopy	Performed the experiments	Investigation	YES
6106798	30175110	H. M. M. Herath	2	involved in writing up the manuscript and all authors read and approved the final manuscript	involved in writing up the manuscript and all authors read and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6106798	30175110	N. P. Weerasinghe	2	involved in writing up the manuscript and all authors read and approved the final manuscript	involved in writing up the manuscript and all authors read and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4412824	25919366	BAN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412824	25919366	BAN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412824	25919366	BAN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412824	25919366	BAN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412824	25919366	BAN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412824	25919366	FMDG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412824	25919366	FMDG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412824	25919366	FMDG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412824	25919366	JAF	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412824	25919366	JAF	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412824	25919366	JAF	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412824	25919366	JAF	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412824	25919366	JLS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412824	25919366	JLS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412824	25919366	JLS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412824	25919366	JLS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412824	25919366	JMA	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412824	25919366	JMA	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412824	25919366	JMA	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412824	25919366	JMC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412824	25919366	JMC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412824	25919366	JMC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412824	25919366	JMC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412824	25919366	JMC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412824	25919366	JSA	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Development of artificial neural network framework	Analyzed the data	Analyzed the data	Formal analysis	YES
4412824	25919366	JSA	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Development of artificial neural network framework	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412824	25919366	JSA	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Development of artificial neural network framework	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412824	25919366	JSA	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Development of artificial neural network framework	Development of artificial neural network framework	Contributed reagents/materials/analysis tools	Software	YES
4412824	25919366	MGJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412824	25919366	MGJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412824	25919366	MGJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412824	25919366	MGJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412824	25919366	MGJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3447702	22943072	AK	2	aided with data collection and analysis|conceived parts of the study, and participated in its design and coordination as well as helped to draft the manuscript	aided with data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3447702	22943072	AK	2	aided with data collection and analysis|conceived parts of the study, and participated in its design and coordination as well as helped to draft the manuscript	conceived parts of the study, and participated in its design and coordination as well as helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
3447702	22943072	AKT	2	aided with data collection and analysis|conceived parts of the study, and participated in its design and coordination as well as helped to draft the manuscript	aided with data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3447702	22943072	AKT	2	aided with data collection and analysis|conceived parts of the study, and participated in its design and coordination as well as helped to draft the manuscript	conceived parts of the study, and participated in its design and coordination as well as helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
3447702	22943072	AT	2	aided with data collection and analysis|conceived parts of the study, and participated in its design and coordination as well as helped to draft the manuscript	aided with data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3447702	22943072	AT	2	aided with data collection and analysis|conceived parts of the study, and participated in its design and coordination as well as helped to draft the manuscript	conceived parts of the study, and participated in its design and coordination as well as helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
3447702	22943072	KSP	2	aided with data collection and analysis|conceived parts of the study, and participated in its design and coordination as well as helped to draft the manuscript	aided with data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3447702	22943072	KSP	2	aided with data collection and analysis|conceived parts of the study, and participated in its design and coordination as well as helped to draft the manuscript	conceived parts of the study, and participated in its design and coordination as well as helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
3447702	22943072	MC	2	conceived parts of the study, and participated in its design and coordination as well as helped to draft the manuscript|provided the supplements	conceived parts of the study, and participated in its design and coordination as well as helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
3447702	22943072	MC	2	conceived parts of the study, and participated in its design and coordination as well as helped to draft the manuscript|provided the supplements	provided the supplements	-	-	NO
3447702	22943072	SS	2	was the principle investigator of the study|conceived parts of the study, and participated in its design and coordination as well as helped to draft the manuscript	was the principle investigator of the study	-	-	NO
3447702	22943072	SS	2	was the principle investigator of the study|conceived parts of the study, and participated in its design and coordination as well as helped to draft the manuscript	conceived parts of the study, and participated in its design and coordination as well as helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
5568174	28830339	FK	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5568174	28830339	FK	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5568174	28830339	FK	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5568174	28830339	FK	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5568174	28830339	JC	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5568174	28830339	JZ	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5568174	28830339	JZ	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5568174	28830339	JZ	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5568174	28830339	JZ	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5568174	28830339	LY	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5568174	28830339	LY	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5568174	28830339	LY	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5568174	28830339	LY	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5568174	28830339	WL	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5568174	28830339	WL	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5568174	28830339	WL	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5568174	28830339	WL	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5568174	28830339	YT	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5656503	29071431	EZ	2	conducted the study and wrote the first and final draft of the article	conducted the study and wrote the first and final draft of the article	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5656503	29071431	JB	2	assisted in the conduction of the spect scans and writing of the article	assisted in the conduction of the spect scans and writing of the article	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5656503	29071431	JDS	2	assisted in analyzing the video recordings and writing of the article	assisted in analyzing the video recordings and writing of the article	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5656503	29071431	MAJT	2	assisted with the study protocol, conduction of the study, and writing of the article	assisted with the study protocol, conduction of the study, and writing of the article	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5656503	29071431	MS	2	assisted in analyzing the video recordings and writing of the article	assisted in analyzing the video recordings and writing of the article	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5656503	29071431	YEMD	2	assisted in analyzing the video recordings and writing of the article	assisted in analyzing the video recordings and writing of the article	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3459729	22726625	CH	2	participated sample analysis and manuscript editing	participated sample analysis and manuscript editing	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
3459729	22726625	DM	2	assisted in study supervision and coordination and was involved in data analysis and editing the manuscript	assisted in study supervision and coordination and was involved in data analysis and editing the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Project administration|Supervision|Writing - Review & Editing	YES
3459729	22726625	JRS	2	participated sample analysis and manuscript editing	participated sample analysis and manuscript editing	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
3459729	22726625	TP	2	was involved in participant recruitment, data collection and analysis|were involved in participant recruitment, data collection and analysis	was involved in participant recruitment, data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3459729	22726625	TP	2	was involved in participant recruitment, data collection and analysis|were involved in participant recruitment, data collection and analysis	were involved in participant recruitment, data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3459729	22726625	TPP	2	assisted in the design of the study, participant recruitment, study management, data collection and analysis and was the primary author of the manuscript	assisted in the design of the study, participant recruitment, study management, data collection and analysis and was the primary author of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
3459729	22726625	WCL	2	were involved in participant recruitment, data collection and analysis	were involved in participant recruitment, data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3459729	22726625	YPP	2	conceived of the study, participated in its design and coordination and helped to draft the manuscript	conceived of the study, participated in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
5704370	29218054	CW	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5704370	29218054	J-ZL	PLoS52	designed the experiments|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5704370	29218054	J-ZL	PLoS52	designed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5704370	29218054	JP	PLoS52	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5704370	29218054	JW	PLoS52	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5704370	29218054	LZ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5704370	29218054	MN	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5704370	29218054	The authors	PLoS52	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	Performed the experiments	Investigation	YES
5704370	29218054	Y-FS	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5704370	29218054	YL	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
6260533	30538998	All of the authors	2	participated in data collection, analysis, and interpretation and critically evaluated and approved the manuscript	participated in data collection, analysis, and interpretation and critically evaluated and approved the manuscript	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6260533	30538998	Daniel Melese Desalegn	2	critically reviewed and made progressive suggestions from the design to final write up of the result	critically reviewed and made progressive suggestions from the design to final write up of the result	Conceived and designed the experiments|Wrote the paper	-	YES
6260533	30538998	Kassu Desta Tullu	2	critically reviewed and made progressive suggestions from the design to final write up of the result	critically reviewed and made progressive suggestions from the design to final write up of the result	Conceived and designed the experiments|Wrote the paper	-	YES
6260533	30538998	Kumera Terfa Kitila	2	conceived and designed the study protocol, collected data, performed analysis, and interpreted data	conceived and designed the study protocol, collected data, performed analysis, and interpreted data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation|Methodology	YES
6260533	30538998	Lemi Mosisa Sori	2	critically reviewed and made progressive suggestions from the design to final write up of the result	critically reviewed and made progressive suggestions from the design to final write up of the result	Conceived and designed the experiments|Wrote the paper	-	YES
4412825	25919028	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412825	25919028	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4412825	25919028	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4412825	25919028	CMT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412825	25919028	CMT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412825	25919028	CMT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412825	25919028	CMT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412825	25919028	EV	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4412825	25919028	EV	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4412825	25919028	GS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4412825	25919028	GS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4412825	25919028	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412825	25919028	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412825	25919028	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412825	25919028	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412825	25919028	LM	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4412825	25919028	LM	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4412825	25919028	LML	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4412825	25919028	LML	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4412825	25919028	LRV	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412825	25919028	LS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412825	25919028	LS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412825	25919028	LW	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4412825	25919028	LW	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4412825	25919028	MLC	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4412825	25919028	MLC	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4412825	25919028	MT	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4412825	25919028	MT	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4412825	25919028	QGD	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4412825	25919028	QGD	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4412825	25919028	RD	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412825	25919028	RP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412825	25919028	RP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412825	25919028	RP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412825	25919028	RP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412825	25919028	SG	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4412825	25919028	SG	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4412825	25919028	SR	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412825	25919028	SR	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412825	25919028	WB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1871613	17534434	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1871613	17534434	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1871613	17534434	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1871613	17534434	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1871613	17534434	HT	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1871613	17534434	MR	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1871613	17534434	PP	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1871613	17534434	PP	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1871613	17534434	SB	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1871613	17534434	SB	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3461468	22569090	BPG	2	participated in the data acquisition and analysis and was a reviewer of the manuscript	participated in the data acquisition and analysis and was a reviewer of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
3461468	22569090	CGM	2	participated in the concept and design, carried out the data acquisition and was a reviewer of the manuscript	participated in the concept and design, carried out the data acquisition and was a reviewer of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Review & Editing	YES
3461468	22569090	JAV	2	participated in the data acquisition and analysis and was a reviewer of the manuscript	participated in the data acquisition and analysis and was a reviewer of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
3461468	22569090	JDC	2	participated in the concept and design, carried out the data acquisition and was the main writer of the manuscript	participated in the concept and design, carried out the data acquisition and was the main writer of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
3461468	22569090	JJS	2	participated in the concept and design, carried out the data analysis and was a reviewer of the manuscript	participated in the concept and design, carried out the data analysis and was a reviewer of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Review & Editing	YES
5660009	29080017	AB	2	performed the metabolite analysis	performed the metabolite analysis	Performed the experiments	Investigation	YES
5660009	29080017	AD	2	participated in the conception of study	participated in the conception of study	Conceived and designed the experiments	Conceptualization	YES
5660009	29080017	AK	2	performed the image analysis and dosimetry calculations	performed the image analysis and dosimetry calculations	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
5660009	29080017	BK	2	participated in the image analysis	participated in the image analysis	Analyzed the data	Visualization	YES
5660009	29080017	CT	2	imaging and plasma and urine sample collection	imaging and plasma and urine sample collection	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
5660009	29080017	HJ	2	developed the radiotracer synthesis, performed metabolite analysis, and drafted the manuscript	developed the radiotracer synthesis, performed metabolite analysis, and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5660009	29080017	JB-G	2	participated in the conception of study	participated in the conception of study	Conceived and designed the experiments	Conceptualization	YES
5660009	29080017	K-WP	2	contributed in the conception of study and data interpretation	contributed in the conception of study and data interpretation	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Resources	YES
5660009	29080017	KD	2	participated in the research coordination and clinical data collection	participated in the research coordination and clinical data collection	Performed the experiments	Investigation|Project administration	YES
5660009	29080017	MP	2	participated in the radiotracer synthesis	participated in the radiotracer synthesis	-	-	NO
5660009	29080017	NS	2	performed the image analysis	performed the image analysis	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
5660009	29080017	SR	2	contributed in the conception of study and data interpretation	contributed in the conception of study and data interpretation	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Resources	YES
5660009	29080017	TD	2	conceived of the study and participated in its design and coordination and helped to draft the manuscript	conceived of the study and participated in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
5660009	29080017	TG	2	performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
5660009	29080017	VL	2	contributed to the conception of study and helped to draft the manuscript	contributed to the conception of study and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5568196	28830354	AP	2	collected and analyzed the volatile data	collected and analyzed the volatile data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5568196	28830354	CC	2	conceived the study|collected and analyzed the genotypic data|drafted the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5568196	28830354	CC	2	conceived the study|collected and analyzed the genotypic data|drafted the manuscript	collected and analyzed the genotypic data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5568196	28830354	CC	2	conceived the study|collected and analyzed the genotypic data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5568196	28830354	EAB	2	collected and analyzed the volatile data	collected and analyzed the volatile data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5568196	28830354	FGG	2	conceived the study|developed the mapping population|drafted the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5568196	28830354	FGG	2	conceived the study|developed the mapping population|drafted the manuscript	developed the mapping population	-	-	NO
5568196	28830354	FGG	2	conceived the study|developed the mapping population|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5568196	28830354	JB	2	conceived the study|collected and analyzed the volatile data	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5568196	28830354	JB	2	conceived the study|collected and analyzed the volatile data	collected and analyzed the volatile data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5568196	28830354	QY	2	collected and analyzed the genotypic data	collected and analyzed the genotypic data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5568196	28830354	YY	2	conceived the study|collected and analyzed the volatile data|collected and analyzed the genotypic data|drafted the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5568196	28830354	YY	2	conceived the study|collected and analyzed the volatile data|collected and analyzed the genotypic data|drafted the manuscript	collected and analyzed the volatile data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5568196	28830354	YY	2	conceived the study|collected and analyzed the volatile data|collected and analyzed the genotypic data|drafted the manuscript	collected and analyzed the genotypic data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5568196	28830354	YY	2	conceived the study|collected and analyzed the volatile data|collected and analyzed the genotypic data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5704371	29218055	All authors	2	listed have made a substantial, direct and intellectual contribution to the work, and approved it for publication	listed have made a substantial, direct and intellectual contribution to the work, and approved it for publication	-	-	NO
4546119	26297438	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4546119	26297438	CS	2	substantially contributed to conception and design of the conducted experiments	substantially contributed to conception and design of the conducted experiments	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
4546119	26297438	JW	2	collected and calculated all data, created the graphs and figures and drafted this manuscript	collected and calculated all data, created the graphs and figures and drafted this manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Visualization|Writing - Original Draft	YES
4546119	26297438	RH	2	substantially contributed to conception and design of the conducted experiments	substantially contributed to conception and design of the conducted experiments	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
4546119	26297438	TM	2	conducted several shake flask experiments to evaluate the surfactin productivity of different bacillus strains	conducted several shake flask experiments to evaluate the surfactin productivity of different bacillus strains	Performed the experiments	Investigation	YES
4546119	26297438	WY	2	conducted his master thesis under the supervision of jw and contributed the data of the first shake flask experiments and fermentations	conducted his master thesis under the supervision of jw and contributed the data of the first shake flask experiments and fermentations	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources|Supervision	YES
1872046	17534436	AS	PLoS5	Manager	Manager	-	Project administration	YES
1872046	17534436	AT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1872046	17534436	AT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1872046	17534436	AT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1872046	17534436	CG	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1872046	17534436	CG	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1872046	17534436	ES	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1872046	17534436	GD	PLoS5	Conceived and designed the experiments|Analyzed the data|Collected the psychometric data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1872046	17534436	GD	PLoS5	Conceived and designed the experiments|Analyzed the data|Collected the psychometric data	Analyzed the data	Analyzed the data	Formal analysis	YES
1872046	17534436	GD	PLoS5	Conceived and designed the experiments|Analyzed the data|Collected the psychometric data	Collected the psychometric data	Performed the experiments	Investigation	YES
1872046	17534436	GF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1872046	17534436	GF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1872046	17534436	GF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1872046	17534436	GF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1872046	17534436	LP	PLoS5	Collected the psychometric data	Collected the psychometric data	Performed the experiments	Investigation	YES
1872046	17534436	VC	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4412830	25919286	ANE	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Interpretation of data analysis|Critical review of manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4412830	25919286	ANE	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Interpretation of data analysis|Critical review of manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412830	25919286	ANE	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Interpretation of data analysis|Critical review of manuscript	Interpretation of data analysis	Analyzed the data	Formal analysis	YES
4412830	25919286	ANE	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Interpretation of data analysis|Critical review of manuscript	Critical review of manuscript	Wrote the paper	Writing - Review & Editing	YES
4412830	25919286	CBS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Interpretation of data analysis|Critical review of manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412830	25919286	CBS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Interpretation of data analysis|Critical review of manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412830	25919286	CBS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Interpretation of data analysis|Critical review of manuscript	Interpretation of data analysis	Analyzed the data	Formal analysis	YES
4412830	25919286	CBS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Interpretation of data analysis|Critical review of manuscript	Critical review of manuscript	Wrote the paper	Writing - Review & Editing	YES
4412830	25919286	JHE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Interpretation of data analysis|Critical review of manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412830	25919286	JHE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Interpretation of data analysis|Critical review of manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4412830	25919286	JHE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Interpretation of data analysis|Critical review of manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4412830	25919286	JHE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Interpretation of data analysis|Critical review of manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412830	25919286	JHE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Interpretation of data analysis|Critical review of manuscript	Interpretation of data analysis	Analyzed the data	Formal analysis	YES
4412830	25919286	JHE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Interpretation of data analysis|Critical review of manuscript	Critical review of manuscript	Wrote the paper	Writing - Review & Editing	YES
3464793	22704463	BD	2	participated in the design of the study and manuscript preparation	participated in the design of the study and manuscript preparation	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3464793	22704463	BT	2	participated in the design of the study, recruitment of subjects, data collection, data analysis and drafted the manuscript	participated in the design of the study, recruitment of subjects, data collection, data analysis and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
3464793	22704463	GC	2	participated in the design of the study, data collection, data analysis, statistical analysis and helped draft the manuscript	participated in the design of the study, data collection, data analysis, statistical analysis and helped draft the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
3464793	22704463	KH	2	assisted in the recruitment of subjects, data collection and data analysis	assisted in the recruitment of subjects, data collection and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3464793	22704463	LA	2	participated in the design of the study and manuscript preparation	participated in the design of the study and manuscript preparation	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3464793	22704463	SC	2	assisted in the design of the study, recruitment of subjects, data collection and data analysis	assisted in the design of the study, recruitment of subjects, data collection and data analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5660010	29080056	All the authors	2	contributed to the writing of the article and approved the final version	contributed to the writing of the article and approved the final version	Wrote the paper	Writing - Original Draft	YES
5660010	29080056	ES	2	supervised the study	supervised the study	-	Supervision	YES
5660010	29080056	GH	2	conducted the experiments, performed the data analysis, and wrote the manuscript	conducted the experiments, performed the data analysis, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5660010	29080056	HI	2	assisted in the experiments	assisted in the experiments	Performed the experiments	Investigation	YES
5660010	29080056	HK	2	assisted in the data analysis	assisted in the data analysis	Analyzed the data	Formal analysis	YES
5660010	29080056	JH	2	supervised the study	supervised the study	-	Supervision	YES
5660010	29080056	KI	2	assisted in the experiments	assisted in the experiments	Performed the experiments	Investigation	YES
5660010	29080056	KM	2	assisted in the experiments	assisted in the experiments	Performed the experiments	Investigation	YES
5660010	29080056	MI	2	assisted in the experiments	assisted in the experiments	Performed the experiments	Investigation	YES
5660010	29080056	SN	2	assisted in the experiments	assisted in the experiments	Performed the experiments	Investigation	YES
5660010	29080056	TW	2	conducted the experiments, performed the data analysis, and wrote the manuscript	conducted the experiments, performed the data analysis, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5660010	29080056	YK	2	assisted in the experiments	assisted in the experiments	Performed the experiments	Investigation	YES
4605203	26491667	Alison L. Marshall	2	contributed to study design, paper review, appraisal, and editing	contributed to study design, paper review, appraisal, and editing	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
4605203	26491667	Carol A. Maher	2	contributed to interpretation, paper review, appraisal, and editing	contributed to interpretation, paper review, appraisal, and editing	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4605203	26491667	Mandy Schippers	2	contributed to study design, data collection, paper review, appraisal, and editing	contributed to study design, data collection, paper review, appraisal, and editing	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Methodology|Resources|Writing - Review & Editing	YES
4605203	26491667	Steven M. Phail	2	contributed to research idea conception, study design, data analysis and interpretation, and principal paper preparation, as well as paper review, appraisal, and editing	contributed to research idea conception, study design, data analysis and interpretation, and principal paper preparation, as well as paper review, appraisal, and editing	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Methodology|Resources|Writing - Review & Editing	YES
5568289	28830360	FM	PLoS52	conceived and designed the experiments|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5568289	28830360	FM	PLoS52	conceived and designed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5568289	28830360	MP	PLoS52	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5568289	28830360	PL	PLoS52	performed the western blot experiments	performed the western blot experiments	Performed the experiments	Investigation	YES
5568289	28830360	QL	PLoS52	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5568289	28830360	QW	PLoS52	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5568289	28830360	WC	PLoS52	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5568289	28830360	XJ	PLoS52	performed the western blot experiments	performed the western blot experiments	Performed the experiments	Investigation	YES
5568289	28830360	XZ	PLoS52	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
1872047	17534437	DY	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1872047	17534437	KE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1872047	17534437	KE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1872047	17534437	KE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1872047	17534437	KE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1872047	17534437	KK	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1872047	17534437	LD	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5704539	29218053	BH	PLoS52	wrote the python scripts|analyzed the data	wrote the python scripts	Contributed reagents/materials/analysis tools|Wrote the paper	Software|Writing - Original Draft	YES
5704539	29218053	BH	PLoS52	wrote the python scripts|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5704539	29218053	DP	PLoS52	tested the pipeline	tested the pipeline	Performed the experiments	Investigation	YES
5704539	29218053	GS	PLoS52	designed the pipeline|prepared the manuscript	designed the pipeline	Conceived and designed the experiments	-	YES
5704539	29218053	GS	PLoS52	designed the pipeline|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5704539	29218053	XL	PLoS52	designed the pipeline|tested the pipeline|analyzed the data|prepared the manuscript	designed the pipeline	Conceived and designed the experiments	-	YES
5704539	29218053	XL	PLoS52	designed the pipeline|tested the pipeline|analyzed the data|prepared the manuscript	tested the pipeline	Performed the experiments	Investigation	YES
5704539	29218053	XL	PLoS52	designed the pipeline|tested the pipeline|analyzed the data|prepared the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5704539	29218053	XL	PLoS52	designed the pipeline|tested the pipeline|analyzed the data|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
3465223	22992437	BS	7	laboratory analyses, data collection, manuscript revision	laboratory analyses, data collection, manuscript revision	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
3465223	22992437	FF	7	2nd supervising physician, blood sampling, manuscript revision	2nd supervising physician, blood sampling, manuscript revision	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Review & Editing	YES
3465223	22992437	GS	7	supervising physician, blood sampling, manuscript revision	supervising physician, blood sampling, manuscript revision	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Review & Editing	YES
3465223	22992437	JG	7	laboratory analyses, manuscript revision	laboratory analyses, manuscript revision	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
3465223	22992437	KS	7	performance diagnostics, manuscript revision	performance diagnostics, manuscript revision	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
3465223	22992437	ML	7	principal investigator, development of overall research plan/study protocol, project management and study oversight, statistical analyses, preparation of manuscript	principal investigator, development of overall research plan/study protocol, project management and study oversight, statistical analyses, preparation of manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Funding acquisition|Methodology|Project administration|Supervision|Writing - Original Draft	YES
3465223	22992437	SB	7	blood sampling, laboratory logistics, statistical analyses, manuscript revision	blood sampling, laboratory logistics, statistical analyses, manuscript revision	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Project administration|Writing - Review & Editing	YES
3465223	22992437	SH	7	laboratory analyses, preparation of manuscript	laboratory analyses, preparation of manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4412835	25919458	HZ	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412835	25919458	HZ	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4412835	25919458	LJ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412835	25919458	LJ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412835	25919458	LJ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412835	25919458	LJ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412835	25919458	MG	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4412835	25919458	MG	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412835	25919458	TZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412835	25919458	TZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412835	25919458	TZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412835	25919458	TZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5668221	29098485	All authors	2	participated in the study planning, data analysis, and drafting of the manuscript and approved the final version	participated in the study planning, data analysis, and drafting of the manuscript and approved the final version	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5668221	29098485	MA	2	wrote the code and developed the program	wrote the code and developed the program	Contributed reagents/materials/analysis tools|Wrote the paper	Software|Writing - Original Draft	YES
5705610	29225609	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5705610	29225609	The authors	2	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	Performed the experiments	Investigation	YES
3467174	22857787	BY	2	assessed laboratory variables and collected data	assessed laboratory variables and collected data	Performed the experiments	Investigation	YES
3467174	22857787	JL	2	recruited the subjects and guided the physical training and nutritional supplementation	recruited the subjects and guided the physical training and nutritional supplementation	Performed the experiments	Investigation|Supervision	YES
3467174	22857787	JMS	2	coordinated the study	coordinated the study	-	Project administration	YES
3467174	22857787	RL	2	recruited the subjects and guided the physical training and nutritional supplementation	recruited the subjects and guided the physical training and nutritional supplementation	Performed the experiments	Investigation|Supervision	YES
3467174	22857787	TH	2	assessed laboratory variables and collected data	assessed laboratory variables and collected data	Performed the experiments	Investigation	YES
3467174	22857787	YL	2	designed the study, conducted the investigations and analyzed the data	designed the study, conducted the investigations and analyzed the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
4412836	25919457	BBM	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412836	25919457	BBM	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412836	25919457	GT	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412836	25919457	GT	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412836	25919457	GT	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412836	25919457	IR	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412836	25919457	IR	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412836	25919457	LL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412836	25919457	LL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412836	25919457	LL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412836	25919457	LL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412836	25919457	PML	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4412836	25919457	PT	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4412836	25919457	TO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412836	25919457	TO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412836	25919457	TO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412836	25919457	TO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1876256	17551572	KF	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1876256	17551572	KF	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1876256	17551572	KS	PLoS5	Performed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1876256	17551572	KS	PLoS5	Performed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1876256	17551572	PB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1876256	17551572	SB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1876256	17551572	SB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1876256	17551572	SB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1876256	17551572	SB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1876256	17551572	SK	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1876256	17551572	SP	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1876256	17551572	SP	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1876256	17551572	SP	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1876256	17551572	VP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1876256	17551572	WS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1876256	17551572	WS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1876256	17551572	WS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1876256	17551572	WS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6013806	30155023	C.S.	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
6013806	30155023	C.S.S.	2	designed the research, and wrote the manuscript|performed experiments and edited the manuscript	designed the research, and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
6013806	30155023	C.S.S.	2	designed the research, and wrote the manuscript|performed experiments and edited the manuscript	performed experiments and edited the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
6013806	30155023	I.P.H.	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
6013806	30155023	J.D.W.	2	designed the research, and wrote the manuscript	designed the research, and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
6013806	30155023	J.K.R.	2	performed experiments and edited the manuscript	performed experiments and edited the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
6013806	30155023	M.A.H.	2	designed the research, and wrote the manuscript|performed experiments and edited the manuscript	designed the research, and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
6013806	30155023	M.A.H.	2	designed the research, and wrote the manuscript|performed experiments and edited the manuscript	performed experiments and edited the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
6013806	30155023	M.K.	2	performed experiments and edited the manuscript	performed experiments and edited the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
6013806	30155023	N.A.P.	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
6013806	30155023	R.A.D.B.	2	designed the research, and wrote the manuscript	designed the research, and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
6013806	30155023	R.J.S.	2	advised on the research and edited the manuscript	advised on the research and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
6013806	30155023	S.G.R.	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
6013806	30155023	S.S.	2	performed experiments and edited the manuscript	performed experiments and edited the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
6013806	30155023	S.T.Y.	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
6013806	30155023	V.B.N.	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
4549370	26307214	All authors	2	have read and approved the final manuscript	have read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4549370	26307214	JSCAJ	2	played a major role for sample collection and overall experimental procedures of this study	played a major role for sample collection and overall experimental procedures of this study	Performed the experiments	Investigation	YES
4549370	26307214	MMB	2	participated in data analysis and drafting of the manuscript	participated in data analysis and drafting of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4549370	26307214	SGVP	2	participated in data analysis and drafting of the manuscript	participated in data analysis and drafting of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4549370	26307214	TC	2	involved in the design and organization of the study and interpreted the results	involved in the design and organization of the study and interpreted the results	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology|Project administration	YES
5693838	29150726	AB	2	helped with data collection and analysis	helped with data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5693838	29150726	AG	2	helped with data collection and analysis	helped with data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5693838	29150726	All authors	2	contributed to the drafting of the manuscript, and all authors read and approved the final manuscript	contributed to the drafting of the manuscript, and all authors read and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5693838	29150726	GB	2	contributed to the concept and design of the study	contributed to the concept and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5693838	29150726	LE	2	helped with data collection and analysis	helped with data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5693838	29150726	LV	2	contributed to the concept and design of the study|helped with data collection and analysis|performed data analysis	contributed to the concept and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5693838	29150726	LV	2	contributed to the concept and design of the study|helped with data collection and analysis|performed data analysis	helped with data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5693838	29150726	LV	2	contributed to the concept and design of the study|helped with data collection and analysis|performed data analysis	performed data analysis	Analyzed the data	Formal analysis	YES
5693838	29150726	MB	2	contributed to the concept and design of the study	contributed to the concept and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5693838	29150726	MK	2	contributed to the concept and design of the study	contributed to the concept and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5693838	29150726	MRI	2	images of healthy controls	images of healthy controls	Analyzed the data	Visualization	YES
5693838	29150726	MU	2	helped with data collection and analysis	helped with data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5693838	29150726	NA	2	contributed to the concept and design of the study	contributed to the concept and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5693838	29150726	PB	2	contributed to the concept and design of the study	contributed to the concept and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5693838	29150726	RR	2	carried out polymorphism genotyping	carried out polymorphism genotyping	Performed the experiments	Investigation	YES
5693838	29150726	SL	2	was responsible for radiopharmaceutical production	was responsible for radiopharmaceutical production	-	-	NO
5693838	29150726	SZ	2	contributed to the concept and design of the study	contributed to the concept and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5705611	29225607	GKP	2	conceived the project|analyzed data and wrote the manuscript	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5705611	29225607	GKP	2	conceived the project|analyzed data and wrote the manuscript	analyzed data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5705611	29225607	HS	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5705611	29225607	KK	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5705611	29225607	PK	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5705611	29225607	SKJ	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5705611	29225607	SKS	2	performed experiments|analyzed data and wrote the manuscript	performed experiments	Performed the experiments	Investigation	YES
5705611	29225607	SKS	2	performed experiments|analyzed data and wrote the manuscript	analyzed data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3469378	22607394	All authors	2	were responsible for the study design, data collection, statistical analysis, and preparation of the manuscript	were responsible for the study design, data collection, statistical analysis, and preparation of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5568309	28830340	BZ	2	designed the experiment|assisted with data interpretation and edited and approved all draft manuscript versions	designed the experiment	Conceived and designed the experiments	Methodology	YES
5568309	28830340	BZ	2	designed the experiment|assisted with data interpretation and edited and approved all draft manuscript versions	assisted with data interpretation and edited and approved all draft manuscript versions	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5568309	28830340	CM	2	designed the experiment|carried out the experiments, analyzed the data and drafted the manuscript	designed the experiment	Conceived and designed the experiments	Methodology	YES
5568309	28830340	CM	2	designed the experiment|carried out the experiments, analyzed the data and drafted the manuscript	carried out the experiments, analyzed the data and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3470991	22928989	BS	2	participated in the design of the study, carried out the data collection, performed the statistical analyses and drafted the manuscript	participated in the design of the study, carried out the data collection, performed the statistical analyses and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
3470991	22928989	CS	2	conceived of the study, participated in its design and helped draft the manuscript|conceived of the study, participated in its design and helped draft the manuscript	conceived of the study, participated in its design and helped draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
3470991	22928989	CS	2	conceived of the study, participated in its design and helped draft the manuscript|conceived of the study, participated in its design and helped draft the manuscript	conceived of the study, participated in its design and helped draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
3470991	22928989	RCH	2	helped to draft the manuscript	helped to draft the manuscript	Wrote the paper	Writing - Original Draft	YES
4412837	25919290	MWF	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412837	25919290	RP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412837	25919290	RP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4412837	25919290	RP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4412837	25919290	RP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4412837	25919290	VG	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4412837	25919290	VG	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1876257	17551573	AM	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1876257	17551573	DM	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1876257	17551573	KF	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1876257	17551573	SK	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5705623	29225610	GG	2	subsequently contributed to produce the final version	subsequently contributed to produce the final version	-	-	NO
5705623	29225610	JK	2	subsequently contributed to produce the final version	subsequently contributed to produce the final version	-	-	NO
4573741	26384341	AEM	2	participated in the design of the experiments and helped to draft the manuscript	participated in the design of the experiments and helped to draft the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
4573741	26384341	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4573741	26384341	GE	2	supervised the project and commented the manuscript	supervised the project and commented the manuscript	-	Supervision	YES
4573741	26384341	JPMS	2	conceived the project and commented the manuscript	conceived the project and commented the manuscript	Conceived and designed the experiments	Conceptualization	YES
4573741	26384341	JS	2	helped to design the cloning strategy and commented the manuscript	helped to design the cloning strategy and commented the manuscript	Conceived and designed the experiments|Performed the experiments	Investigation	YES
4573741	26384341	JVS	2	carried out the fermenter experiments	carried out the fermenter experiments	Performed the experiments	Investigation	YES
4573741	26384341	KSV	2	carried out construction of the strains, performed the fermenter experiments and drafted the manuscript	carried out construction of the strains, performed the fermenter experiments and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4573741	26384341	Novel Economic	2	eco-efficient processes for the production of itaconic and fumaric acid	eco-efficient processes for the production of itaconic and fumaric acid	-	-	NO
4573741	26384341	RW	2	conceived, supervised and participated in the design of the project and contributed to write the manuscript	conceived, supervised and participated in the design of the project and contributed to write the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Supervision|Writing - Original Draft	YES
5701906	29177913	AM	2	conceived the study, participated in its design and coordination, and wrote the manuscript	conceived the study, participated in its design and coordination, and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
5701906	29177913	DP	2	carried out mri studies and analysis	carried out mri studies and analysis	Performed the experiments	Investigation	YES
5701906	29177913	JLL	2	participated in the design and coordination of the study	participated in the design and coordination of the study	Conceived and designed the experiments	Methodology|Project administration	YES
5701906	29177913	KRP	2	carried out the synthesis of the radiotracer and radiosynthesis	carried out the synthesis of the radiotracer and radiosynthesis	Performed the experiments	Investigation	YES
5701906	29177913	LC	2	carried out pet studies, imaging analysis, and immunohistochemistry	carried out pet studies, imaging analysis, and immunohistochemistry	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
3832967	24288472	Chao Shen	2	contributed equally to this work	contributed equally to this work	-	-	NO
3832967	24288472	Rong Xie	2	contributed equally to this work	contributed equally to this work	-	-	NO
3832967	24288472	Weimin Bao	2	contributed equally to this work	contributed equally to this work	-	-	NO
3832967	24288472	Xiaoyun Cao	2	contributed equally to this work	contributed equally to this work	-	-	NO
3472188	22992430	ACP	2	was involved in research design, analysis and manuscript preparation	was involved in research design, analysis and manuscript preparation	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
3472188	22992430	DL	2	was the study coordinator and was involved in research design, data collection and analysis, as well as manuscript preparation	was the study coordinator and was involved in research design, data collection and analysis, as well as manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Project administration|Writing - Original Draft	YES
3472188	22992430	ER	2	assisted in data analysis and manuscript development	assisted in data analysis and manuscript development	Analyzed the data	Formal analysis	YES
3472188	22992430	SS	2	assisted in research design	assisted in research design	Conceived and designed the experiments	-	YES
5568313	28830350	AR	PLoS5	Manuscript writing	Manuscript writing	Wrote the paper	Writing - Original Draft	YES
5568313	28830350	BCB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Manuscript writing	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5568313	28830350	BCB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Manuscript writing	Performed the experiments	Performed the experiments	Investigation	YES
5568313	28830350	BCB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Manuscript writing	Analyzed the data	Analyzed the data	Formal analysis	YES
5568313	28830350	BCB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Manuscript writing	Manuscript writing	Wrote the paper	Writing - Original Draft	YES
5568313	28830350	BNT	PLoS5	Manuscript writing	Manuscript writing	Wrote the paper	Writing - Original Draft	YES
5568313	28830350	DE	PLoS5	Analyzed the data|Manuscript writing	Analyzed the data	Analyzed the data	Formal analysis	YES
5568313	28830350	DE	PLoS5	Analyzed the data|Manuscript writing	Manuscript writing	Wrote the paper	Writing - Original Draft	YES
5568313	28830350	NK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Manuscript writing	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5568313	28830350	NK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Manuscript writing	Performed the experiments	Performed the experiments	Investigation	YES
5568313	28830350	NK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Manuscript writing	Analyzed the data	Analyzed the data	Formal analysis	YES
5568313	28830350	NK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Manuscript writing	Manuscript writing	Wrote the paper	Writing - Original Draft	YES
5568313	28830350	NR	PLoS5	Manuscript writing	Manuscript writing	Wrote the paper	Writing - Original Draft	YES
5568313	28830350	NV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Manuscript writing	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5568313	28830350	NV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Manuscript writing	Performed the experiments	Performed the experiments	Investigation	YES
5568313	28830350	NV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Manuscript writing	Analyzed the data	Analyzed the data	Formal analysis	YES
5568313	28830350	NV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Manuscript writing	Manuscript writing	Wrote the paper	Writing - Original Draft	YES
5568313	28830350	PS	PLoS5	Performed the experiments|Analyzed the data|Manuscript writing	Performed the experiments	Performed the experiments	Investigation	YES
5568313	28830350	PS	PLoS5	Performed the experiments|Analyzed the data|Manuscript writing	Analyzed the data	Analyzed the data	Formal analysis	YES
5568313	28830350	PS	PLoS5	Performed the experiments|Analyzed the data|Manuscript writing	Manuscript writing	Wrote the paper	Writing - Original Draft	YES
5568313	28830350	RKS	PLoS5	Manuscript writing	Manuscript writing	Wrote the paper	Writing - Original Draft	YES
5568313	28830350	RS	PLoS5	Manuscript writing	Manuscript writing	Wrote the paper	Writing - Original Draft	YES
5568313	28830350	SB	PLoS5	Manuscript writing	Manuscript writing	Wrote the paper	Writing - Original Draft	YES
5568313	28830350	TA	PLoS5	Performed the experiments|Analyzed the data|Manuscript writing	Performed the experiments	Performed the experiments	Investigation	YES
5568313	28830350	TA	PLoS5	Performed the experiments|Analyzed the data|Manuscript writing	Analyzed the data	Analyzed the data	Formal analysis	YES
5568313	28830350	TA	PLoS5	Performed the experiments|Analyzed the data|Manuscript writing	Manuscript writing	Wrote the paper	Writing - Original Draft	YES
1876258	17551574	JA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1876258	17551574	JA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1876258	17551574	JA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1876258	17551574	RA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1876258	17551574	RA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1876258	17551574	RA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4414059	25919756	AS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4414059	25919756	JSV	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414059	25919756	JSV	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414059	25919756	JSV	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414059	25919756	MK	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414059	25919756	MK	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414059	25919756	MK	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414059	25919756	NS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414059	25919756	NS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414059	25919756	NS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414059	25919756	NS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5705942	29225608	CY	1	Experiment designed|Data analysis|Experiment|Manuscript writing	Experiment designed	Conceived and designed the experiments	Methodology	YES
5705942	29225608	CY	1	Experiment designed|Data analysis|Experiment|Manuscript writing	Data analysis	Analyzed the data	Formal analysis	YES
5705942	29225608	CY	1	Experiment designed|Data analysis|Experiment|Manuscript writing	Experiment	-	-	NO
5705942	29225608	CY	1	Experiment designed|Data analysis|Experiment|Manuscript writing	Manuscript writing	Wrote the paper	Writing - Original Draft	YES
5705942	29225608	FS	1	Data analysis	Data analysis	Analyzed the data	Formal analysis	YES
5705942	29225608	HW	1	Experiment	Experiment	-	-	NO
5705942	29225608	LZ	1	Experiment designed|Data analysis|Experiment|Manuscript writing	Experiment designed	Conceived and designed the experiments	Methodology	YES
5705942	29225608	LZ	1	Experiment designed|Data analysis|Experiment|Manuscript writing	Data analysis	Analyzed the data	Formal analysis	YES
5705942	29225608	LZ	1	Experiment designed|Data analysis|Experiment|Manuscript writing	Experiment	-	-	NO
5705942	29225608	LZ	1	Experiment designed|Data analysis|Experiment|Manuscript writing	Manuscript writing	Wrote the paper	Writing - Original Draft	YES
5705942	29225608	QG	1	Experiment	Experiment	-	-	NO
5705942	29225608	SL	1	Experiment	Experiment	-	-	NO
5705942	29225608	SM	1	Experiment	Experiment	-	-	NO
5705942	29225608	ZY	1	Experiment	Experiment	-	-	NO
3479057	22971354	ARJ	2	served as the study coordinator, oversaw all testing, and assisted in data analysis and writing of the manuscript	served as the study coordinator, oversaw all testing, and assisted in data analysis and writing of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Project administration|Supervision|Writing - Original Draft	YES
3479057	22971354	AS	2	assisted with data collection	assisted with data collection	Performed the experiments	Investigation	YES
3479057	22971354	CM	2	served as a collaborating scientist	served as a collaborating scientist	-	-	NO
3479057	22971354	CR	2	served as lab coordinator and oversaw data collection and quality control of the study	served as lab coordinator and oversaw data collection and quality control of the study	Performed the experiments	Data curation|Investigation|Project administration|Supervision|Validation	YES
3479057	22971354	EG	2	assisted with data collection and reviewed and approved nutritional records as the studies registered dietitian	assisted with data collection and reviewed and approved nutritional records as the studies registered dietitian	Performed the experiments	Investigation	YES
3479057	22971354	JF	2	supervised the biopsy procedures	supervised the biopsy procedures	Performed the experiments	Investigation|Supervision	YES
3479057	22971354	JMO	2	assisted in data collection and statistical analysis	assisted in data collection and statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3479057	22971354	MG	2	assisted in experimental design, data analysis, and manuscript preparation	assisted in experimental design, data analysis, and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
3479057	22971354	RBK	2	served as principal investigator and contributed to the design of the study, statistical analysis, manuscript preparation, and procurement of external funding	served as principal investigator and contributed to the design of the study, statistical analysis, manuscript preparation, and procurement of external funding	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Funding acquisition|Methodology|Writing - Original Draft	YES
3479057	22971354	SR	2	supervised the biopsy procedures	supervised the biopsy procedures	Performed the experiments	Investigation|Supervision	YES
4573961	26384340	A-BB	PLoS52	have designed the work|analysed the data|reviewed the manuscript and made very important scientific contributions	have designed the work	Conceived and designed the experiments	-	YES
4573961	26384340	A-BB	PLoS52	have designed the work|analysed the data|reviewed the manuscript and made very important scientific contributions	analysed the data	Analyzed the data	Formal analysis	YES
4573961	26384340	A-BB	PLoS52	have designed the work|analysed the data|reviewed the manuscript and made very important scientific contributions	reviewed the manuscript and made very important scientific contributions	Wrote the paper	Writing - Review & Editing	YES
4573961	26384340	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4573961	26384340	FKS	PLoS52	analysed the data|reviewed the manuscript and made very important scientific contributions	analysed the data	Analyzed the data	Formal analysis	YES
4573961	26384340	FKS	PLoS52	analysed the data|reviewed the manuscript and made very important scientific contributions	reviewed the manuscript and made very important scientific contributions	Wrote the paper	Writing - Review & Editing	YES
4573961	26384340	RB	PLoS52	have designed the work|carried out the experiment|analysed the data|wrote the manuscript|reviewed the manuscript and made very important scientific contributions	have designed the work	Conceived and designed the experiments	-	YES
4573961	26384340	RB	PLoS52	have designed the work|carried out the experiment|analysed the data|wrote the manuscript|reviewed the manuscript and made very important scientific contributions	carried out the experiment	Performed the experiments	Investigation	YES
4573961	26384340	RB	PLoS52	have designed the work|carried out the experiment|analysed the data|wrote the manuscript|reviewed the manuscript and made very important scientific contributions	analysed the data	Analyzed the data	Formal analysis	YES
4573961	26384340	RB	PLoS52	have designed the work|carried out the experiment|analysed the data|wrote the manuscript|reviewed the manuscript and made very important scientific contributions	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4573961	26384340	RB	PLoS52	have designed the work|carried out the experiment|analysed the data|wrote the manuscript|reviewed the manuscript and made very important scientific contributions	reviewed the manuscript and made very important scientific contributions	Wrote the paper	Writing - Review & Editing	YES
4573961	26384340	XH	PLoS52	have designed the work|carried out the experiment|analysed the data|wrote the manuscript|reviewed the manuscript and made very important scientific contributions	have designed the work	Conceived and designed the experiments	-	YES
4573961	26384340	XH	PLoS52	have designed the work|carried out the experiment|analysed the data|wrote the manuscript|reviewed the manuscript and made very important scientific contributions	carried out the experiment	Performed the experiments	Investigation	YES
4573961	26384340	XH	PLoS52	have designed the work|carried out the experiment|analysed the data|wrote the manuscript|reviewed the manuscript and made very important scientific contributions	analysed the data	Analyzed the data	Formal analysis	YES
4573961	26384340	XH	PLoS52	have designed the work|carried out the experiment|analysed the data|wrote the manuscript|reviewed the manuscript and made very important scientific contributions	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4573961	26384340	XH	PLoS52	have designed the work|carried out the experiment|analysed the data|wrote the manuscript|reviewed the manuscript and made very important scientific contributions	reviewed the manuscript and made very important scientific contributions	Wrote the paper	Writing - Review & Editing	YES
5701907	29178006	AAG	2	collected the data	collected the data	Performed the experiments	Investigation	YES
5701907	29178006	APP	2	designed the study and prepared the manuscript|did the statistical analysis	designed the study and prepared the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5701907	29178006	APP	2	designed the study and prepared the manuscript|did the statistical analysis	did the statistical analysis	Analyzed the data	Formal analysis	YES
5701907	29178006	CG	2	gave technical support and conceptual advice	gave technical support and conceptual advice	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5701907	29178006	ChG	2	collected the data	collected the data	Performed the experiments	Investigation	YES
5701907	29178006	DCB	2	designed the study and prepared the manuscript|did the statistical analysis	designed the study and prepared the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5701907	29178006	DCB	2	designed the study and prepared the manuscript|did the statistical analysis	did the statistical analysis	Analyzed the data	Formal analysis	YES
5701907	29178006	FM	2	designed the study and prepared the manuscript|did the statistical analysis	designed the study and prepared the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5701907	29178006	FM	2	designed the study and prepared the manuscript|did the statistical analysis	did the statistical analysis	Analyzed the data	Formal analysis	YES
5701907	29178006	MG	2	collected the data	collected the data	Performed the experiments	Investigation	YES
5701907	29178006	MM	2	collected the data	collected the data	Performed the experiments	Investigation	YES
5701907	29178006	OG	2	gave technical support and conceptual advice	gave technical support and conceptual advice	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5701907	29178006	PAK	2	designed the study and prepared the manuscript	designed the study and prepared the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5701907	29178006	RRB	2	did the statistical analysis	did the statistical analysis	Analyzed the data	Formal analysis	YES
5568329	28830345	H.J.L.	PLoS52	reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5568329	28830345	J.L.T.	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5568329	28830345	L.D.G.	PLoS52	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5568329	28830345	Q.S.J.	PLoS52	conceived and designed the study|reviewed and edited the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5568329	28830345	Q.S.J.	PLoS52	conceived and designed the study|reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5568329	28830345	Z.P.	PLoS52	conceived and designed the study|performed the experiments|wrote the current manuscript|reviewed and edited the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5568329	28830345	Z.P.	PLoS52	conceived and designed the study|performed the experiments|wrote the current manuscript|reviewed and edited the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5568329	28830345	Z.P.	PLoS52	conceived and designed the study|performed the experiments|wrote the current manuscript|reviewed and edited the manuscript	wrote the current manuscript	Wrote the paper	Writing - Original Draft	YES
5568329	28830345	Z.P.	PLoS52	conceived and designed the study|performed the experiments|wrote the current manuscript|reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
1876259	17551577	AD	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1876259	17551577	MC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5706409	29225611	CL	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5706409	29225611	DZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5706409	29225611	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Edited the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5706409	29225611	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Edited the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
5706409	29225611	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Edited the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5706409	29225611	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Edited the manuscript	Edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5706409	29225611	LJ	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5706409	29225611	QL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5706409	29225611	XG	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
5706409	29225611	XG	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5706409	29225611	YS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
3483284	23046855	HA	2	implemented the study and collected the data	implemented the study and collected the data	Performed the experiments	Investigation	YES
3483284	23046855	JF	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3483284	23046855	JR	2	participated in the design of the study and in the writing of this manuscript	participated in the design of the study and in the writing of this manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3483284	23046855	NA	2	participated in the design of the study and in the writing of this manuscript	participated in the design of the study and in the writing of this manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3483284	23046855	RS	2	was the principle investigator of the study and designed the study|implemented the study and collected the data|participated in the design of the study and in the writing of this manuscript	was the principle investigator of the study and designed the study	Conceived and designed the experiments	Methodology	YES
3483284	23046855	RS	2	was the principle investigator of the study and designed the study|implemented the study and collected the data|participated in the design of the study and in the writing of this manuscript	implemented the study and collected the data	Performed the experiments	Investigation	YES
3483284	23046855	RS	2	was the principle investigator of the study and designed the study|implemented the study and collected the data|participated in the design of the study and in the writing of this manuscript	participated in the design of the study and in the writing of this manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3483284	23046855	SB	2	participated in the design of the study and in the writing of this manuscript	participated in the design of the study and in the writing of this manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4414267	25923708	AV	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414267	25923708	AV	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414267	25923708	CR-G	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414267	25923708	CR-G	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414267	25923708	CX	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414267	25923708	CX	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414267	25923708	EL-E	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414267	25923708	EL-E	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414267	25923708	FM-H	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414267	25923708	FM-H	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414267	25923708	FM-H	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414267	25923708	FM-H	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414267	25923708	G-BV	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Obtained permission and approval of health authorities	Performed the experiments	Performed the experiments	Investigation	YES
4414267	25923708	G-BV	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Obtained permission and approval of health authorities	Analyzed the data	Analyzed the data	Formal analysis	YES
4414267	25923708	G-BV	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Obtained permission and approval of health authorities	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414267	25923708	G-BV	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Obtained permission and approval of health authorities	Obtained permission and approval of health authorities	-	Project administration	YES
4414267	25923708	GV	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414267	25923708	GV	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414267	25923708	GV	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414267	25923708	IV-H	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414267	25923708	IV-H	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414267	25923708	IV-H	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414267	25923708	JM-O	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414267	25923708	JM-O	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414267	25923708	JM-O	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414267	25923708	MEH-C	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414267	25923708	MEH-C	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414267	25923708	MER-M	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414267	25923708	MER-M	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414267	25923708	MER-M	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414267	25923708	MR-V	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414267	25923708	MR-V	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414267	25923708	MR-V	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414267	25923708	MR-V	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414267	25923708	PM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Obtained permission and approval of health authorities	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414267	25923708	PM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Obtained permission and approval of health authorities	Analyzed the data	Analyzed the data	Formal analysis	YES
4414267	25923708	PM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Obtained permission and approval of health authorities	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414267	25923708	PM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Obtained permission and approval of health authorities	Obtained permission and approval of health authorities	-	Project administration	YES
1876261	17551578	AG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1876261	17551578	AG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1876261	17551578	AG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1876261	17551578	CR	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1876261	17551578	CR	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1876261	17551578	FT	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1876261	17551578	FT	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1876261	17551578	MC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1876261	17551578	MC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1876261	17551578	MC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1876261	17551578	MT	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1876261	17551578	MT	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1876261	17551578	RP	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1876261	17551578	RP	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5708653	29230228	C. All	PLoS52	authors discussed and approved the final manuscript	authors discussed and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5708653	29230228	JS	PLoS52	contributed to the data analysis	contributed to the data analysis	Analyzed the data	Formal analysis	YES
5708653	29230228	LL	PLoS52	contributed to the data analysis	contributed to the data analysis	Analyzed the data	Formal analysis	YES
5708653	29230228	NY	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5708653	29230228	WZ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5708653	29230228	XW	PLoS52	contributed to the data analysis	contributed to the data analysis	Analyzed the data	Formal analysis	YES
5568345	28830381	GB	2	provided data on blood and intestinal parameters	provided data on blood and intestinal parameters	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5568345	28830381	HQ	2	provided data on blood and intestinal parameters|supervised the project	provided data on blood and intestinal parameters	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5568345	28830381	HQ	2	provided data on blood and intestinal parameters|supervised the project	supervised the project	-	Supervision	YES
5568345	28830381	ILHL	2	provided data on blood and intestinal parameters|wrote the manuscript with|supervised the project	provided data on blood and intestinal parameters	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5568345	28830381	ILHL	2	provided data on blood and intestinal parameters|wrote the manuscript with|supervised the project	wrote the manuscript with	Wrote the paper	Writing - Original Draft	YES
5568345	28830381	ILHL	2	provided data on blood and intestinal parameters|wrote the manuscript with|supervised the project	supervised the project	-	Supervision	YES
5568345	28830381	LC	2	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5568345	28830381	LL	2	conceived and designed the study|helped with the wrote the manuscript with|supervised the project	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5568345	28830381	LL	2	conceived and designed the study|helped with the wrote the manuscript with|supervised the project	helped with the wrote the manuscript with	Wrote the paper	Writing - Original Draft	YES
5568345	28830381	LL	2	conceived and designed the study|helped with the wrote the manuscript with|supervised the project	supervised the project	-	Supervision	YES
5568345	28830381	MCP	2	provided data on blood and intestinal parameters	provided data on blood and intestinal parameters	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5568345	28830381	MJ	2	extracted rna and performed control quality|provided data on blood and intestinal parameters	extracted rna and performed control quality	Performed the experiments	Investigation	YES
5568345	28830381	MJ	2	extracted rna and performed control quality|provided data on blood and intestinal parameters	provided data on blood and intestinal parameters	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5568345	28830381	NI	2	was the project data manager	was the project data manager	Analyzed the data	Data curation|Project administration	YES
5568345	28830381	PM	2	provided data on blood and intestinal parameters	provided data on blood and intestinal parameters	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5568345	28830381	VR	2	extracted rna and performed control quality	extracted rna and performed control quality	Performed the experiments	Investigation	YES
5568345	28830381	VV	2	helped with the wrote the manuscript with	helped with the wrote the manuscript with	Wrote the paper	Writing - Original Draft	YES
5568345	28830381	YB	2	supervised the performance testing, from animal production to biological sampling	supervised the performance testing, from animal production to biological sampling	Performed the experiments	Investigation|Supervision	YES
5568345	28830381	YL	2	provided the transcriptomic data set	provided the transcriptomic data set	Contributed reagents/materials/analysis tools	Resources	YES
5568345	28830381	YY	2	wrote the manuscript with	wrote the manuscript with	Wrote the paper	Writing - Original Draft	YES
5705539	29185067	ES	2	performed dose calculations using raydose software	performed dose calculations using raydose software	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Software	YES
5705539	29185067	MDAr	2	conceived and designed the study, oversaw all phases of the research, analyzed data, and wrote the paper	conceived and designed the study, oversaw all phases of the research, analyzed data, and wrote the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Supervision|Writing - Original Draft	YES
5705539	29185067	MT	2	assisted with evaluation of results and manuscript preparation	assisted with evaluation of results and manuscript preparation	Wrote the paper	Writing - Original Draft	YES
5705539	29185067	NP	2	performed dose calculations using raydose software	performed dose calculations using raydose software	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Software	YES
5705539	29185067	RP	2	assisted with analysis and interpretation of results	assisted with analysis and interpretation of results	Analyzed the data	Formal analysis	YES
5705539	29185067	TLD	2	calibration, interpretation of the results, and revision of the manuscript	calibration, interpretation of the results, and revision of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
1876262	17551579	JC	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1876262	17551579	JC	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1876262	17551579	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1876262	17551579	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1876262	17551579	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1876262	17551579	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1876262	17551579	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1876262	17551579	SH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1876262	17551579	SH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1876262	17551579	SH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414268	25923113	CK-E	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414268	25923113	FG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414268	25923113	FG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414268	25923113	FG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414268	25923113	FG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414268	25923113	ICvH	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414268	25923113	LSdV	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414268	25923113	MJNLB	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414268	25923113	TA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414268	25923113	TA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414268	25923113	TA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414268	25923113	TA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414268	25923113	YK	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414268	25923113	YK	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4573974	26384343	AFP	2	carried out real time pcr analysis	carried out real time pcr analysis	Performed the experiments	Investigation	YES
4573974	26384343	All authors	2	have read and approved the final manuscript	have read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4573974	26384343	KM	2	carried out linkage mapping analysis	carried out linkage mapping analysis	Performed the experiments	Investigation	YES
4573974	26384343	KN	2	constructed libraries for next generation sequence	constructed libraries for next generation sequence	Performed the experiments	Investigation	YES
4573974	26384343	KY	2	contributed next generation sequence analysis and de novo assemble	contributed next generation sequence analysis and de novo assemble	Performed the experiments	Investigation	YES
4573974	26384343	NK	2	carried out real time pcr analysis	carried out real time pcr analysis	Performed the experiments	Investigation	YES
4573974	26384343	SN	2	contributed next generation sequence analysis and de novo assemble	contributed next generation sequence analysis and de novo assemble	Performed the experiments	Investigation	YES
4573974	26384343	SS	2	carried out real time pcr analysis	carried out real time pcr analysis	Performed the experiments	Investigation	YES
4573974	26384343	YS	2	carried out all protein purification, sequence analysis, and phylogenetic analysis	carried out all protein purification, sequence analysis, and phylogenetic analysis	Performed the experiments	Investigation	YES
5711811	29230232	AH	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5711811	29230232	AP	PLoS52	conceived this study|performed the experiments|analyzed data|wrote the manuscript	conceived this study	Conceived and designed the experiments	Conceptualization	YES
5711811	29230232	AP	PLoS52	conceived this study|performed the experiments|analyzed data|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5711811	29230232	AP	PLoS52	conceived this study|performed the experiments|analyzed data|wrote the manuscript	analyzed data	Analyzed the data	Formal analysis	YES
5711811	29230232	AP	PLoS52	conceived this study|performed the experiments|analyzed data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5711811	29230232	CL	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5711811	29230232	GC	PLoS52	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5711811	29230232	HP	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5711811	29230232	HS	PLoS52	analyzed data|wrote the manuscript	analyzed data	Analyzed the data	Formal analysis	YES
5711811	29230232	HS	PLoS52	analyzed data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5711811	29230232	J-CK	PLoS52	conceived this study|performed the experiments|analyzed data|wrote the manuscript	conceived this study	Conceived and designed the experiments	Conceptualization	YES
5711811	29230232	J-CK	PLoS52	conceived this study|performed the experiments|analyzed data|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5711811	29230232	J-CK	PLoS52	conceived this study|performed the experiments|analyzed data|wrote the manuscript	analyzed data	Analyzed the data	Formal analysis	YES
5711811	29230232	J-CK	PLoS52	conceived this study|performed the experiments|analyzed data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5711811	29230232	J-IK	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5711811	29230232	KK	PLoS52	conceived this study|performed the experiments|analyzed data|wrote the manuscript	conceived this study	Conceived and designed the experiments	Conceptualization	YES
5711811	29230232	KK	PLoS52	conceived this study|performed the experiments|analyzed data|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5711811	29230232	KK	PLoS52	conceived this study|performed the experiments|analyzed data|wrote the manuscript	analyzed data	Analyzed the data	Formal analysis	YES
5711811	29230232	KK	PLoS52	conceived this study|performed the experiments|analyzed data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5711811	29230232	NY	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5711811	29230232	TL	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5711811	29230232	Y-WL	PLoS52	analyzed data|wrote the manuscript	analyzed data	Analyzed the data	Formal analysis	YES
5711811	29230232	Y-WL	PLoS52	analyzed data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5711811	29230232	YL	PLoS52	conceived this study|performed the experiments|wrote the manuscript	conceived this study	Conceived and designed the experiments	Conceptualization	YES
5711811	29230232	YL	PLoS52	conceived this study|performed the experiments|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5711811	29230232	YL	PLoS52	conceived this study|performed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5712296	29198065	AA	2	contributed to the study design, data analysis, and critical revision of the manuscript	contributed to the study design, data analysis, and critical revision of the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Review & Editing	YES
5712296	29198065	BZ	2	contributed to the study design, data analysis, and critical revision of the manuscript	contributed to the study design, data analysis, and critical revision of the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Review & Editing	YES
5712296	29198065	DV	2	contributed to the study preparation, experimentation, and critical revision of the manuscript	contributed to the study preparation, experimentation, and critical revision of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5712296	29198065	JL	2	contributed to the study design, data analysis, and critical revision of the manuscript	contributed to the study design, data analysis, and critical revision of the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Review & Editing	YES
5712296	29198065	JP	2	contributed to the study preparation, experimentation, and critical revision of the manuscript	contributed to the study preparation, experimentation, and critical revision of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5712296	29198065	KF	2	contributed to the study preparation, experimentation, and critical revision of the manuscript	contributed to the study preparation, experimentation, and critical revision of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5712296	29198065	MS	2	designed the study, conducted the experiments, analysed the data, drafted the manuscript, and revised the manuscript per co-author suggestions	designed the study, conducted the experiments, analysed the data, drafted the manuscript, and revised the manuscript per co-author suggestions	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5712296	29198065	NKP	2	contributed to the study preparation, experimentation, and critical revision of the manuscript	contributed to the study preparation, experimentation, and critical revision of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5712296	29198065	OK	2	designed the study, conducted the experiments, analysed the data, drafted the manuscript, and revised the manuscript per co-author suggestions	designed the study, conducted the experiments, analysed the data, drafted the manuscript, and revised the manuscript per co-author suggestions	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5712296	29198065	VJ	2	contributed to the study preparation, experimentation, and critical revision of the manuscript	contributed to the study preparation, experimentation, and critical revision of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5568362	28830361	GH	2	designed the research and discussed the data|wrote the manuscript	designed the research and discussed the data	Conceived and designed the experiments	Methodology	YES
5568362	28830361	GH	2	designed the research and discussed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5568362	28830361	LPI	2	designed the research and discussed the data|performed the bioinformatic research and analyzed the data|wrote the manuscript	designed the research and discussed the data	Conceived and designed the experiments	Methodology	YES
5568362	28830361	LPI	2	designed the research and discussed the data|performed the bioinformatic research and analyzed the data|wrote the manuscript	performed the bioinformatic research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5568362	28830361	LPI	2	designed the research and discussed the data|performed the bioinformatic research and analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5568362	28830361	MR	2	designed and performed the experimental research	designed and performed the experimental research	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5568362	28830361	WBB	2	designed the research and discussed the data	designed the research and discussed the data	Conceived and designed the experiments	Methodology	YES
1876795	17534439	AD	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1876795	17534439	AD	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1876795	17534439	AS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1876795	17534439	BL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1876795	17534439	CB	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1876795	17534439	CB	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1876795	17534439	CG	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1876795	17534439	CI	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1876795	17534439	CM	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1876795	17534439	CM	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1876795	17534439	CW	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1876795	17534439	CW	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1876795	17534439	DE	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1876795	17534439	DE	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1876795	17534439	DE	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1876795	17534439	DM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1876795	17534439	DM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1876795	17534439	DM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1876795	17534439	DS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1876795	17534439	DW	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1876795	17534439	FL	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1876795	17534439	FL	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1876795	17534439	GG	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1876795	17534439	HL	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1876795	17534439	HL	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1876795	17534439	JD	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1876795	17534439	JG	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1876795	17534439	JG	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1876795	17534439	KR	PLoS5	Conceived and designed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1876795	17534439	KR	PLoS5	Conceived and designed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1876795	17534439	KR	PLoS5	Conceived and designed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1876795	17534439	KR	PLoS5	Conceived and designed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1876795	17534439	KR	PLoS5	Conceived and designed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1876795	17534439	KS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1876795	17534439	KS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1876795	17534439	LA	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1876795	17534439	LB	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1876795	17534439	LB	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1876795	17534439	ME	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1876795	17534439	ME	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1876795	17534439	MF	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1876795	17534439	MF	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1876795	17534439	MM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1876795	17534439	MP	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1876795	17534439	MS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1876795	17534439	NF	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1876795	17534439	RM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1876795	17534439	RR	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1876795	17534439	RR	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1876795	17534439	RS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1876795	17534439	RS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1876795	17534439	RS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1876795	17534439	RS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1876795	17534439	SH	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1876795	17534439	SL	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1876795	17534439	SL	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1876795	17534439	SY	PLoS5	Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1876795	17534439	SY	PLoS5	Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1876795	17534439	TH	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1876795	17534439	TH	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1876795	17534439	TP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1876795	17534439	VH	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1876795	17534439	VH	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5711826	29230233	AKS	2	involved in conceptualization of the project, study design, bio-informatics analyses, data compilation, manuscript writing, critical inputs and finalization of the manuscript	involved in conceptualization of the project, study design, bio-informatics analyses, data compilation, manuscript writing, critical inputs and finalization of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5711826	29230233	AUS	2	was involved in critical inputs and finalization of the manuscript	was involved in critical inputs and finalization of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5711826	29230233	All authors	2	have read and approved the final manuscript	have read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5711826	29230233	BB	2	involved in conceptualization of the project, study design, bio-informatics analyses, data compilation, manuscript writing, critical inputs and finalization of the manuscript|were involved wet lab experiments and bio-informatics analysis	involved in conceptualization of the project, study design, bio-informatics analyses, data compilation, manuscript writing, critical inputs and finalization of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5711826	29230233	BB	2	involved in conceptualization of the project, study design, bio-informatics analyses, data compilation, manuscript writing, critical inputs and finalization of the manuscript|were involved wet lab experiments and bio-informatics analysis	were involved wet lab experiments and bio-informatics analysis	-	Formal analysis	YES
5711826	29230233	DK	2	were involved wet lab experiments and bio-informatics analysis	were involved wet lab experiments and bio-informatics analysis	-	Formal analysis	YES
5711826	29230233	HD	2	were involved wet lab experiments and bio-informatics analysis	were involved wet lab experiments and bio-informatics analysis	-	Formal analysis	YES
5711826	29230233	KR	2	were involved wet lab experiments and bio-informatics analysis	were involved wet lab experiments and bio-informatics analysis	-	Formal analysis	YES
5711826	29230233	RA	2	involved in conceptualization of the project, study design, bio-informatics analyses, data compilation, manuscript writing, critical inputs and finalization of the manuscript	involved in conceptualization of the project, study design, bio-informatics analyses, data compilation, manuscript writing, critical inputs and finalization of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5711826	29230233	SG	2	was involved in critical inputs and finalization of the manuscript	was involved in critical inputs and finalization of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5711826	29230233	SS	2	were involved wet lab experiments and bio-informatics analysis	were involved wet lab experiments and bio-informatics analysis	-	Formal analysis	YES
5711826	29230233	TS	2	involved in conceptualization of the project, study design, bio-informatics analyses, data compilation, manuscript writing, critical inputs and finalization of the manuscript	involved in conceptualization of the project, study design, bio-informatics analyses, data compilation, manuscript writing, critical inputs and finalization of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
4414269	25923526	AC	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4414269	25923526	AC	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4414269	25923526	AC	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414269	25923526	CMB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4414269	25923526	CMB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4414269	25923526	CMB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414269	25923526	DG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414269	25923526	DG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4414269	25923526	DG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414269	25923526	MUM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414269	25923526	MUM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414269	25923526	MUM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414269	25923526	MUM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5716959	29209997	HI	2	performed the radiosynthesis	performed the radiosynthesis	Performed the experiments	Investigation	YES
5716959	29209997	KA	2	participated in the study coordination and in the design of the study and drafted the manuscript	participated in the study coordination and in the design of the study and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft	YES
5716959	29209997	MI	2	performed the pet experiments	performed the pet experiments	Performed the experiments	Investigation	YES
5716959	29209997	SM	2	performed the pet experiments	performed the pet experiments	Performed the experiments	Investigation	YES
5716959	29209997	TR	2	participated in the design of the study, performed pet, mc-1 measurement, and drafted the manuscript	participated in the design of the study, performed pet, mc-1 measurement, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5716959	29209997	YK	2	performed the histological study	performed the histological study	Performed the experiments	Investigation	YES
4605257	26491674	All authors	2	read and approved the final paper	read and approved the final paper	-	-	NO
4605257	26491674	Chang-Han Chen	2	participated in the interpretation of data and conducted immunohistochemistry analysis|coordinated the study and were involved in drafting the paper and revised it critically|contributed equally to this study	participated in the interpretation of data and conducted immunohistochemistry analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4605257	26491674	Chang-Han Chen	2	participated in the interpretation of data and conducted immunohistochemistry analysis|coordinated the study and were involved in drafting the paper and revised it critically|contributed equally to this study	coordinated the study and were involved in drafting the paper and revised it critically	Wrote the paper	Project administration|Writing - Original Draft|Writing - Review & Editing	YES
4605257	26491674	Chang-Han Chen	2	participated in the interpretation of data and conducted immunohistochemistry analysis|coordinated the study and were involved in drafting the paper and revised it critically|contributed equally to this study	contributed equally to this study	-	-	NO
4605257	26491674	Chien-Ting Liu	2	collected the clinical data of patients and performed statistical data analysis	collected the clinical data of patients and performed statistical data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4605257	26491674	Hsin-Ting Tsai	2	participated in the interpretation of data and conducted immunohistochemistry analysis	participated in the interpretation of data and conducted immunohistochemistry analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4605257	26491674	Kun-Ming Rau	2	collected the clinical data of patients and performed statistical data analysis	collected the clinical data of patients and performed statistical data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4605257	26491674	Sheng-Dean Luo	2	conceived the study design, carried out and coordinated immunohistochemical examinations of tumor specimens and data analysis, and drafted the paper	conceived the study design, carried out and coordinated immunohistochemical examinations of tumor specimens and data analysis, and drafted the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Project administration|Writing - Original Draft	YES
4605257	26491674	Tai-Jan Chiu	2	coordinated the study and were involved in drafting the paper and revised it critically|contributed equally to this study	coordinated the study and were involved in drafting the paper and revised it critically	Wrote the paper	Project administration|Writing - Original Draft|Writing - Review & Editing	YES
4605257	26491674	Tai-Jan Chiu	2	coordinated the study and were involved in drafting the paper and revised it critically|contributed equally to this study	contributed equally to this study	-	-	NO
4605257	26491674	Yi-Ching Chen	2	collected the clinical data of patients and performed statistical data analysis	collected the clinical data of patients and performed statistical data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4605257	26491674	Yi-Ju Chen	2	conceived the study design, carried out and coordinated immunohistochemical examinations of tumor specimens and data analysis, and drafted the paper	conceived the study design, carried out and coordinated immunohistochemical examinations of tumor specimens and data analysis, and drafted the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Project administration|Writing - Original Draft	YES
4577490	26391393	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4577490	26391393	BS	2	provided dlc-processing of samples	provided dlc-processing of samples	Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Resources	YES
4577490	26391393	HG	2	conceived of the study, and participated in its design and coordination and helped to draft the manuscript	conceived of the study, and participated in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
4577490	26391393	IB	2	conceived of the study, and participated in its design and coordination and helped to draft the manuscript	conceived of the study, and participated in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
4577490	26391393	NH	2	carried out the microbiological testing and drafted the manuscript	carried out the microbiological testing and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4577490	26391393	RB	2	conceived of the study, and participated in its design and coordination and helped to draft the manuscript	conceived of the study, and participated in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
4577490	26391393	RK	2	provided dlc-processing of samples	provided dlc-processing of samples	Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Resources	YES
4577490	26391393	RvER	2	conceived of the study, and participated in its design and coordination and helped to draft the manuscript	conceived of the study, and participated in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
4577490	26391393	SJ	2	carried out the microbiological testing and drafted the manuscript	carried out the microbiological testing and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
1876806	17551591	AS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1876806	17551591	CG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1876806	17551591	CG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1876806	17551591	CG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1876806	17551591	CG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1876806	17551591	CG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1876806	17551591	EN	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1876806	17551591	GF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1876806	17551591	GF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1876806	17551591	GF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1876806	17551591	JO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1876806	17551591	JO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1876806	17551591	JO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1876806	17551591	KC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1876806	17551591	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1876806	17551591	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1876806	17551591	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5568366	28830355	BG	2	contributed to the content of the database	contributed to the content of the database	Contributed reagents/materials/analysis tools	Resources|Software	YES
5568366	28830355	CC	2	contributed to the content of the database	contributed to the content of the database	Contributed reagents/materials/analysis tools	Resources|Software	YES
5568366	28830355	HDD	2	contributed to the content of the database|wrote the manuscript	contributed to the content of the database	Contributed reagents/materials/analysis tools	Resources|Software	YES
5568366	28830355	HDD	2	contributed to the content of the database|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5568366	28830355	JFU	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5568366	28830355	JS	2	contributed to the content of the database	contributed to the content of the database	Contributed reagents/materials/analysis tools	Resources|Software	YES
5711830	29230229	AC	2	manage the phenomobile acsuisition	manage the phenomobile acsuisition	-	-	NO
5711830	29230229	All authors	2	participated in the discussion	participated in the discussion	-	-	NO
5711830	29230229	BdS	2	manage the phenomobile acsuisition	manage the phenomobile acsuisition	-	-	NO
5711830	29230229	FB	2	manage the phenomobile acsuisition|made very significant revisions	manage the phenomobile acsuisition	-	-	NO
5711830	29230229	FB	2	manage the phenomobile acsuisition|made very significant revisions	made very significant revisions	Wrote the paper	Writing - Review & Editing	YES
5711830	29230229	MH	2	design the flight plan	design the flight plan	Conceived and designed the experiments	-	YES
5711830	29230229	SJ	2	manage the field platform	manage the field platform	-	-	NO
5711830	29230229	SM	2	design the flight plan	design the flight plan	Conceived and designed the experiments	-	YES
5711830	29230229	ST	2	manage the phenomobile acsuisition	manage the phenomobile acsuisition	-	-	NO
5722781	29222707	All authors	2	were actively involved in the interpretation of the data and in the drafting or revising of the manuscript, and all read and approved the final version submitted	were actively involved in the interpretation of the data and in the drafting or revising of the manuscript, and all read and approved the final version submitted	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5722781	29222707	JS	2	contributed to the conception and design|were involved in collecting data|were the driving forces in applying the manual image analyses	contributed to the conception and design	Conceived and designed the experiments	Conceptualization	YES
5722781	29222707	JS	2	contributed to the conception and design|were involved in collecting data|were the driving forces in applying the manual image analyses	were involved in collecting data	Performed the experiments	Investigation	YES
5722781	29222707	JS	2	contributed to the conception and design|were involved in collecting data|were the driving forces in applying the manual image analyses	were the driving forces in applying the manual image analyses	Analyzed the data	Formal analysis|Visualization	YES
5722781	29222707	KB-O	2	went through all anonymized data with the purpose of testing reproducibility and interobserver agreement	went through all anonymized data with the purpose of testing reproducibility and interobserver agreement	Performed the experiments	Investigation|Validation	YES
5722781	29222707	KT	2	were involved in collecting data|were the driving forces in applying the manual image analyses	were involved in collecting data	Performed the experiments	Investigation	YES
5722781	29222707	KT	2	were involved in collecting data|were the driving forces in applying the manual image analyses	were the driving forces in applying the manual image analyses	Analyzed the data	Formal analysis|Visualization	YES
5722781	29222707	LD	2	contributed to the conception and design|were involved in collecting data	contributed to the conception and design	Conceived and designed the experiments	Conceptualization	YES
5722781	29222707	LD	2	contributed to the conception and design|were involved in collecting data	were involved in collecting data	Performed the experiments	Investigation	YES
5722781	29222707	PH-C	2	contributed to the conception and design	contributed to the conception and design	Conceived and designed the experiments	Conceptualization	YES
5722781	29222707	SH	2	contributed to the conception and design|were involved in collecting data	contributed to the conception and design	Conceived and designed the experiments	Conceptualization	YES
5722781	29222707	SH	2	contributed to the conception and design|were involved in collecting data	were involved in collecting data	Performed the experiments	Investigation	YES
5722781	29222707	SJ	2	contributed to the conception and design	contributed to the conception and design	Conceived and designed the experiments	Conceptualization	YES
4414271	25922934	BD	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414271	25922934	CYB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4414271	25922934	DLC	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4414271	25922934	DWY	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414271	25922934	FNW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4414271	25922934	GHS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414271	25922934	GHS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414271	25922934	GMZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414271	25922934	GMZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414271	25922934	GMZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414271	25922934	GMZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414271	25922934	HLZ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414271	25922934	XJQ	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4414271	25922934	YZ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4579157	26395597	AE-C	2	reviewed the results and approved the final version of the manuscript	reviewed the results and approved the final version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4579157	26395597	AM	2	reviewed the results and approved the final version of the manuscript	reviewed the results and approved the final version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4579157	26395597	AR	2	designed, performed and analyzed all experiments in paper	designed, performed and analyzed all experiments in paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
4579157	26395597	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4579157	26395597	JGJ	2	conceived and coordinated the study and wrote the paper|designed, performed and analyzed all experiments in paper	conceived and coordinated the study and wrote the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Project administration|Writing - Original Draft	YES
4579157	26395597	JGJ	2	conceived and coordinated the study and wrote the paper|designed, performed and analyzed all experiments in paper	designed, performed and analyzed all experiments in paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
4579157	26395597	MC	2	reviewed the results and approved the final version of the manuscript	reviewed the results and approved the final version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4579157	26395597	TDP	2	conceived and coordinated the study and wrote the paper|designed, performed and analyzed all experiments in paper	conceived and coordinated the study and wrote the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Project administration|Writing - Original Draft	YES
4579157	26395597	TDP	2	conceived and coordinated the study and wrote the paper|designed, performed and analyzed all experiments in paper	designed, performed and analyzed all experiments in paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
1876807	17551580	AB	PLoS5	Acquired the data from national sources and contributed considerable expertise	Acquired the data from national sources and contributed considerable expertise	Performed the experiments	Investigation	YES
1876807	17551580	DS	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1876807	17551580	IG	PLoS5	Acquired the data from national sources and contributed considerable expertise	Acquired the data from national sources and contributed considerable expertise	Performed the experiments	Investigation	YES
1876807	17551580	LA	PLoS5	Acquired the data from national sources and contributed considerable expertise	Acquired the data from national sources and contributed considerable expertise	Performed the experiments	Investigation	YES
1876807	17551580	SR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1876807	17551580	SR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1876807	17551580	SR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1876807	17551580	VV	PLoS5	Acquired the data from national sources and contributed considerable expertise	Acquired the data from national sources and contributed considerable expertise	Performed the experiments	Investigation	YES
5727003	29234903	ADR	2	are the principal investigators of this research, guarantors of integrity of the entire study design and manuscript writing	are the principal investigators of this research, guarantors of integrity of the entire study design and manuscript writing	Conceived and designed the experiments|Wrote the paper	Conceptualization|Funding acquisition|Methodology|Writing - Original Draft	YES
5727003	29234903	ARJ	2	contributed to the study design and manuscript editing and review	contributed to the study design and manuscript editing and review	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5727003	29234903	CR	2	contributed to the study design and manuscript editing and review	contributed to the study design and manuscript editing and review	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5727003	29234903	CT	2	scans and analyzed the images	scans and analyzed the images	Analyzed the data	Formal analysis|Visualization	YES
5727003	29234903	JCH	2	analyzed the images and performed the dosimetric calculations	analyzed the images and performed the dosimetric calculations	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
5727003	29234903	JCMA	2	produced the cu-64 and performed the quality control of the injectable solution	produced the cu-64 and performed the quality control of the injectable solution	Performed the experiments	Investigation|Validation	YES
5727003	29234903	MAAR	2	are the principal investigators of this research, guarantors of integrity of the entire study design and manuscript writing	are the principal investigators of this research, guarantors of integrity of the entire study design and manuscript writing	Conceived and designed the experiments|Wrote the paper	Conceptualization|Funding acquisition|Methodology|Writing - Original Draft	YES
5727003	29234903	RMH	2	recruited the healthy volunteers	recruited the healthy volunteers	Performed the experiments	Investigation	YES
5568370	28830349	CF	2	implemented the models, analyzed data and wrote the paper	implemented the models, analyzed data and wrote the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5568370	28830349	KZ	2	designed the study, implemented the models, analyzed data and wrote the paper	designed the study, implemented the models, analyzed data and wrote the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5568370	28830349	PC	2	analyzed data and wrote the paper	analyzed data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5568370	28830349	PK	2	implemented the models, analyzed data and wrote the paper	implemented the models, analyzed data and wrote the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5568370	28830349	RK	2	designed the study, analyzed data and wrote the paper	designed the study, analyzed data and wrote the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4605267	26491691	Alexandrine Gautheron	2	contributed equally to this work	contributed equally to this work	-	-	NO
4605267	26491691	Malika Trad	2	contributed equally to this work	contributed equally to this work	-	-	NO
5711853	29230230	JA	2	conducted the field measurements and the collection of samples	conducted the field measurements and the collection of samples	Performed the experiments	Investigation	YES
5711853	29230230	OV-D	2	conducted the field measurements and the collection of samples	conducted the field measurements and the collection of samples	Performed the experiments	Investigation	YES
5711853	29230230	SK	2	carried out the uav flights for the obtainment of aerial measurements|with the contributions from all the other authors	carried out the uav flights for the obtainment of aerial measurements	Performed the experiments	Investigation	YES
5711853	29230230	SK	2	carried out the uav flights for the obtainment of aerial measurements|with the contributions from all the other authors	with the contributions from all the other authors	-	-	NO
1876808	17551581	All of the authors	2	contributed equally to all aspects of this paper	contributed equally to all aspects of this paper	-	-	NO
4414272	25923686	DG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414272	25923686	DG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414272	25923686	DG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414272	25923686	SF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414272	25923686	SF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414272	25923686	SF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414272	25923686	SF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414272	25923686	SF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5569476	28835210	CPC	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5569476	28835210	GZZ	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5569476	28835210	WZG	2	drafted the manuscript|revised the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5569476	28835210	WZG	2	drafted the manuscript|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5736520	29260333	All authors	PLoS52	edited, reviewed, and approved the manuscript	edited, reviewed, and approved the manuscript	Wrote the paper	Writing - Review & Editing	YES
5736520	29260333	DHW	PLoS52	reviewed the patient studies	reviewed the patient studies	-	-	NO
5736520	29260333	KNH	PLoS52	reviewed the patient studies	reviewed the patient studies	-	-	NO
5736520	29260333	LRE	PLoS52	carried out the protocol development and patient recruitment	carried out the protocol development and patient recruitment	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5736520	29260333	MKO	PLoS52	analyzed the data|prepared the manuscript|carried out the protocol development and patient recruitment	analyzed the data	Analyzed the data	Formal analysis	YES
5736520	29260333	MKO	PLoS52	analyzed the data|prepared the manuscript|carried out the protocol development and patient recruitment	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5736520	29260333	MKO	PLoS52	analyzed the data|prepared the manuscript|carried out the protocol development and patient recruitment	carried out the protocol development and patient recruitment	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5736520	29260333	TDT	PLoS52	analyzed the data|carried out the protocol development and patient recruitment	analyzed the data	Analyzed the data	Formal analysis	YES
5736520	29260333	TDT	PLoS52	analyzed the data|carried out the protocol development and patient recruitment	carried out the protocol development and patient recruitment	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5736520	29260333	TNS	PLoS52	carried out the protocol development and patient recruitment	carried out the protocol development and patient recruitment	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5712095	29230231	AF	2	designed the study|supervised the project|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5712095	29230231	AF	2	designed the study|supervised the project|wrote the manuscript	supervised the project	-	Supervision	YES
5712095	29230231	AF	2	designed the study|supervised the project|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5712095	29230231	AK	2	performed the bifc analysis	performed the bifc analysis	Performed the experiments	Investigation	YES
5712095	29230231	All authors	2	reviewed the results and approved the final version of the manuscript	reviewed the results and approved the final version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5712095	29230231	CO	2	designed the study|performed the kinase phosphorylation analysis|performed the bifc analysis|supervised the project|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5712095	29230231	CO	2	designed the study|performed the kinase phosphorylation analysis|performed the bifc analysis|supervised the project|wrote the manuscript	performed the kinase phosphorylation analysis	Performed the experiments	Investigation	YES
5712095	29230231	CO	2	designed the study|performed the kinase phosphorylation analysis|performed the bifc analysis|supervised the project|wrote the manuscript	performed the bifc analysis	Performed the experiments	Investigation	YES
5712095	29230231	CO	2	designed the study|performed the kinase phosphorylation analysis|performed the bifc analysis|supervised the project|wrote the manuscript	supervised the project	-	Supervision	YES
5712095	29230231	CO	2	designed the study|performed the kinase phosphorylation analysis|performed the bifc analysis|supervised the project|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5712095	29230231	JP	2	performed the structural analysis	performed the structural analysis	Performed the experiments	Investigation	YES
5712095	29230231	JT	2	supervised the project	supervised the project	-	Supervision	YES
5712095	29230231	LG	2	performed the kinase phosphorylation analysis	performed the kinase phosphorylation analysis	Performed the experiments	Investigation	YES
5712095	29230231	NA	2	performed the ms analysis	performed the ms analysis	Performed the experiments	Investigation	YES
5712095	29230231	TS	2	performed the kinase phosphorylation analysis	performed the kinase phosphorylation analysis	Performed the experiments	Investigation	YES
1876809	17551593	AR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1876809	17551593	AR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1876809	17551593	AR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1876809	17551593	MA	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1876809	17551593	MA	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1876809	17551593	MA	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1876809	17551593	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1876809	17551593	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1876809	17551593	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1876809	17551593	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1876809	17551593	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1876809	17551593	MV	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1876809	17551593	ST	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1876809	17551593	ST	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5741573	29274016	AK	2	contributed to the study design|contributed to the patient recruitment	contributed to the study design	Conceived and designed the experiments	Methodology	YES
5741573	29274016	AK	2	contributed to the study design|contributed to the patient recruitment	contributed to the patient recruitment	Performed the experiments	Investigation	YES
5741573	29274016	ES	2	contributed to the study design|contributed to data collection|contributed to data analysis and manuscript drafting	contributed to the study design	Conceived and designed the experiments	Methodology	YES
5741573	29274016	ES	2	contributed to the study design|contributed to data collection|contributed to data analysis and manuscript drafting	contributed to data collection	Performed the experiments	Investigation	YES
5741573	29274016	ES	2	contributed to the study design|contributed to data collection|contributed to data analysis and manuscript drafting	contributed to data analysis and manuscript drafting	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5741573	29274016	HH	2	contributed to the patient recruitment	contributed to the patient recruitment	Performed the experiments	Investigation	YES
5741573	29274016	JH	2	contributed to the study design|contributed to data collection|contributed to data analysis and manuscript drafting	contributed to the study design	Conceived and designed the experiments	Methodology	YES
5741573	29274016	JH	2	contributed to the study design|contributed to data collection|contributed to data analysis and manuscript drafting	contributed to data collection	Performed the experiments	Investigation	YES
5741573	29274016	JH	2	contributed to the study design|contributed to data collection|contributed to data analysis and manuscript drafting	contributed to data analysis and manuscript drafting	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5741573	29274016	KM	2	contributed to the study design|contributed to data collection|contributed to data analysis and manuscript drafting	contributed to the study design	Conceived and designed the experiments	Methodology	YES
5741573	29274016	KM	2	contributed to the study design|contributed to data collection|contributed to data analysis and manuscript drafting	contributed to data collection	Performed the experiments	Investigation	YES
5741573	29274016	KM	2	contributed to the study design|contributed to data collection|contributed to data analysis and manuscript drafting	contributed to data analysis and manuscript drafting	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5741573	29274016	MY	2	contributed to the study design|contributed to data collection|contributed to the patient recruitment	contributed to the study design	Conceived and designed the experiments	Methodology	YES
5741573	29274016	MY	2	contributed to the study design|contributed to data collection|contributed to the patient recruitment	contributed to data collection	Performed the experiments	Investigation	YES
5741573	29274016	MY	2	contributed to the study design|contributed to data collection|contributed to the patient recruitment	contributed to the patient recruitment	Performed the experiments	Investigation	YES
5741573	29274016	NT	2	contributed to the study design	contributed to the study design	Conceived and designed the experiments	Methodology	YES
5741573	29274016	TK	2	contributed to the study design|contributed to the patient recruitment	contributed to the study design	Conceived and designed the experiments	Methodology	YES
5741573	29274016	TK	2	contributed to the study design|contributed to the patient recruitment	contributed to the patient recruitment	Performed the experiments	Investigation	YES
5741573	29274016	TO	2	contributed to the patient recruitment	contributed to the patient recruitment	Performed the experiments	Investigation	YES
5712302	29234342	AB	2	performed experiments and data analysis	performed experiments and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5712302	29234342	AL	2	performed experiments and data analysis	performed experiments and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5712302	29234342	All authors	2	contributed to numerous discussions and revised the manuscript	contributed to numerous discussions and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5712302	29234342	EA	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5712302	29234342	JFa	2	performed experiments and data analysis	performed experiments and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5712302	29234342	JFu	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5712302	29234342	KC	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5712302	29234342	LC	2	designed the research|performed experiments and data analysis|wrote the manuscript in close collaboration with all authors	designed the research	Conceived and designed the experiments	Methodology	YES
5712302	29234342	LC	2	designed the research|performed experiments and data analysis|wrote the manuscript in close collaboration with all authors	performed experiments and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5712302	29234342	LC	2	designed the research|performed experiments and data analysis|wrote the manuscript in close collaboration with all authors	wrote the manuscript in close collaboration with all authors	Wrote the paper	Writing - Original Draft	YES
5712302	29234342	XH	2	performed experiments and data analysis	performed experiments and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5712302	29234342	YX	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5712302	29234342	ZH	2	performed experiments and data analysis	performed experiments and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4633474	26538191	Applied Life Sciences	2	kyoto university, japan	kyoto university, japan	-	-	NO
4633474	26538191	NS	2	conducted the enzyme characterization studies	conducted the enzyme characterization studies	Performed the experiments	Investigation	YES
4633474	26538191	P. All	2	authors read and approved the final manuscript	authors read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4633474	26538191	PC	2	carried out the molecular cloning experiments and enzyme purification	carried out the molecular cloning experiments and enzyme purification	Performed the experiments	Investigation	YES
4633474	26538191	PP	2	performed the protein structural analysis work	performed the protein structural analysis work	Performed the experiments	Investigation	YES
4633474	26538191	TP	2	carried out the molecular cloning experiments and enzyme purification|conducted the enzyme characterization studies	carried out the molecular cloning experiments and enzyme purification	Performed the experiments	Investigation	YES
4633474	26538191	TP	2	carried out the molecular cloning experiments and enzyme purification|conducted the enzyme characterization studies	conducted the enzyme characterization studies	Performed the experiments	Investigation	YES
4633474	26538191	WP	2	as her mentor	as her mentor	-	-	NO
5569477	28836940	KA	2	analysed hi-c data	analysed hi-c data	Analyzed the data	Formal analysis	YES
5569477	28836940	KK	2	analysed chip-seq data|wrote the manuscript|planned, coordinated and supervised the project	analysed chip-seq data	Analyzed the data	Formal analysis	YES
5569477	28836940	KK	2	analysed chip-seq data|wrote the manuscript|planned, coordinated and supervised the project	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5569477	28836940	KK	2	analysed chip-seq data|wrote the manuscript|planned, coordinated and supervised the project	planned, coordinated and supervised the project	Conceived and designed the experiments	Conceptualization|Project administration|Supervision	YES
5569477	28836940	SU	2	designed, performed experiments, and analyzed data|wrote the manuscript	designed, performed experiments, and analyzed data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5569477	28836940	SU	2	designed, performed experiments, and analyzed data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5569477	28836940	SV	2	analysed hi-c data	analysed hi-c data	Analyzed the data	Formal analysis	YES
4414273	25923327	GRP	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414273	25923327	GRP	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414273	25923327	KKB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414273	25923327	KKB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414273	25923327	KKB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414273	25923327	KLF	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414273	25923327	KLF	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414273	25923327	MJF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414273	25923327	MJF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414273	25923327	MJF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414273	25923327	MLR	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414273	25923327	MLR	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414273	25923327	MS	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4414273	25923327	REK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414273	25923327	REK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414273	25923327	REK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414273	25923327	TJB	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414273	25923327	TJB	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1876810	17551582	IC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1876810	17551582	IC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1876810	17551582	IC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1876810	17551582	IC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1876810	17551582	IC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1876810	17551582	NF	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1876810	17551582	NF	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1876810	17551582	NF	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5741574	29273939	DAJ	2	participated in the design of the study	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
5741574	29273939	DWH	2	participated in the design of the study	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
5741574	29273939	ET	2	carried out the compartment model analysis|developed the model used to analyze data	carried out the compartment model analysis	Performed the experiments	Investigation|Methodology	YES
5741574	29273939	ET	2	carried out the compartment model analysis|developed the model used to analyze data	developed the model used to analyze data	Performed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5741574	29273939	HK	2	developed the model used to analyze data	developed the model used to analyze data	Performed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5741574	29273939	IS	2	carried out the histology analysis	carried out the histology analysis	Performed the experiments	Investigation	YES
5741574	29273939	IY	2	developed the model used to analyze data	developed the model used to analyze data	Performed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5741574	29273939	JG	2	carried out the compartment model analysis	carried out the compartment model analysis	Performed the experiments	Investigation|Methodology	YES
5741574	29273939	MM	2	developed the model used to analyze data	developed the model used to analyze data	Performed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5741574	29273939	NCD	2	participated in the design of the study	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
5712309	29234336	All authors	2	approved the version to be published|agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	approved the version to be published	-	-	NO
5712309	29234336	All authors	2	approved the version to be published|agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	-	-	NO
5712309	29234336	DX	2	revised it critically for important intellectual content	revised it critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5712309	29234336	LT	2	analyzed and interpretated the data of the work|wrote the manuscript	analyzed and interpretated the data of the work	Analyzed the data	Formal analysis	YES
5712309	29234336	LT	2	analyzed and interpretated the data of the work|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5712309	29234336	NY	2	planned and designed the work	planned and designed the work	Conceived and designed the experiments	Conceptualization	YES
5712309	29234336	SD	2	revised it critically for important intellectual content	revised it critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5712309	29234336	WH	2	analyzed and interpretated the data of the work	analyzed and interpretated the data of the work	Analyzed the data	Formal analysis	YES
5712309	29234336	XF	2	analyzed and interpretated the data of the work	analyzed and interpretated the data of the work	Analyzed the data	Formal analysis	YES
5712309	29234336	XZ	2	revised it critically for important intellectual content	revised it critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4414274	25923109	DR	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414274	25923109	DR	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414274	25923109	DR	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414274	25923109	DR	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414274	25923109	GGC	PLoS5	Conceived and designed the experiments|Wrote the paper|Commented on the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414274	25923109	GGC	PLoS5	Conceived and designed the experiments|Wrote the paper|Commented on the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414274	25923109	GGC	PLoS5	Conceived and designed the experiments|Wrote the paper|Commented on the manuscript	Commented on the manuscript	-	-	NO
4414274	25923109	JJR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414274	25923109	JJR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414274	25923109	JJR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414274	25923109	JJR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414274	25923109	JJR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414274	25923109	JMHA	PLoS5	Conceived and designed the experiments|Wrote the paper|Commented on the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414274	25923109	JMHA	PLoS5	Conceived and designed the experiments|Wrote the paper|Commented on the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414274	25923109	JMHA	PLoS5	Conceived and designed the experiments|Wrote the paper|Commented on the manuscript	Commented on the manuscript	-	-	NO
4414274	25923109	RLL	PLoS5	Conceived and designed the experiments|Commented on the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414274	25923109	RLL	PLoS5	Conceived and designed the experiments|Commented on the manuscript	Commented on the manuscript	-	-	NO
4414274	25923109	RV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414274	25923109	RV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414274	25923109	RV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414274	25923109	RV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414274	25923109	RV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4641145	26556030	ANP	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
4641145	26556030	All the authors	2	read the article and approved the final manuscript	read the article and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4641145	26556030	DK	2	help in the sub-cloning and selecting of transformants	help in the sub-cloning and selecting of transformants	Performed the experiments	Investigation	YES
4641145	26556030	MFL	2	wrote the manuscript and reviewed the manuscript critically	wrote the manuscript and reviewed the manuscript critically	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4641145	26556030	MG	2	wrote the manuscript and reviewed the manuscript critically	wrote the manuscript and reviewed the manuscript critically	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4641145	26556030	MK	2	designed the work|carried out the experiments|analyzed the data and contributed for the statistical analysis|wrote the manuscript and reviewed the manuscript critically	designed the work	Conceived and designed the experiments	-	YES
4641145	26556030	MK	2	designed the work|carried out the experiments|analyzed the data and contributed for the statistical analysis|wrote the manuscript and reviewed the manuscript critically	carried out the experiments	Performed the experiments	Investigation	YES
4641145	26556030	MK	2	designed the work|carried out the experiments|analyzed the data and contributed for the statistical analysis|wrote the manuscript and reviewed the manuscript critically	analyzed the data and contributed for the statistical analysis	Analyzed the data	Formal analysis	YES
4641145	26556030	MK	2	designed the work|carried out the experiments|analyzed the data and contributed for the statistical analysis|wrote the manuscript and reviewed the manuscript critically	wrote the manuscript and reviewed the manuscript critically	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4641145	26556030	VY	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5569538	28835208	BVH	2	performed experiments, bioinformatics analyses and drafted the manuscript	performed experiments, bioinformatics analyses and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5569538	28835208	LD	2	performed experiments, bioinformatics analyses and drafted the manuscript	performed experiments, bioinformatics analyses and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5569538	28835208	RC	2	designed the study and performed field and nutrient analysis	designed the study and performed field and nutrient analysis	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5569538	28835208	SH	2	carried out the karyotype experiment	carried out the karyotype experiment	Performed the experiments	Investigation	YES
5569538	28835208	XL	2	performed experiments, bioinformatics analyses and drafted the manuscript	performed experiments, bioinformatics analyses and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5569538	28835208	XX	2	designed the study and performed field and nutrient analysis	designed the study and performed field and nutrient analysis	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5569538	28835208	YC	2	designed the study and performed field and nutrient analysis	designed the study and performed field and nutrient analysis	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5746495	29285636	BC	2	approved the final content of the manuscript	approved the final content of the manuscript	-	-	NO
5746495	29285636	EE	2	wrote the paper together|have substantial contributions to the conception and design	wrote the paper together	Wrote the paper	Writing - Original Draft	YES
5746495	29285636	EE	2	wrote the paper together|have substantial contributions to the conception and design	have substantial contributions to the conception and design	Conceived and designed the experiments	Conceptualization	YES
5746495	29285636	FB	2	drafted and revised the manuscript critically for important intellectual content	drafted and revised the manuscript critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5746495	29285636	TO	2	wrote the paper together|have substantial contributions to the conception and design	wrote the paper together	Wrote the paper	Writing - Original Draft	YES
5746495	29285636	TO	2	wrote the paper together|have substantial contributions to the conception and design	have substantial contributions to the conception and design	Conceived and designed the experiments	Conceptualization	YES
5746495	29285636	TYE	2	approved the final content of the manuscript	approved the final content of the manuscript	-	-	NO
1876811	17551583	DN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1876811	17551583	DN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1876811	17551583	DN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1876811	17551583	DN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1876811	17551583	DN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1876811	17551583	JM	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1876811	17551583	JM	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1876811	17551583	LH	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1876811	17551583	MJ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1876811	17551583	PG	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1876811	17551583	PG	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1876811	17551583	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1876811	17551583	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1876811	17551583	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1876811	17551583	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1876811	17551583	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4641146	26556029	All authors	PLoS52	revised and approved the final manuscript	revised and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4641146	26556029	HC	PLoS52	designed and performed the experiments and analyzed the data|wrote the paper	designed and performed the experiments and analyzed the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
4641146	26556029	HC	PLoS52	designed and performed the experiments and analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4641146	26556029	HY	PLoS52	contributed reagents/materials/analysis tools and data analysis	contributed reagents/materials/analysis tools and data analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
4641146	26556029	MM	PLoS52	contributed reagents/materials/analysis tools and data analysis	contributed reagents/materials/analysis tools and data analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
4641146	26556029	YH	PLoS52	designed and performed the experiments and analyzed the data	designed and performed the experiments and analyzed the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5571580	28836939	BD	2	carried out all the data gathering, analysis and wrote the original manuscript draft	carried out all the data gathering, analysis and wrote the original manuscript draft	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5571580	28836939	BH	2	carried out twin modeling studies	carried out twin modeling studies	Performed the experiments	Investigation|Methodology	YES
5571580	28836939	IM	2	carried out dna sequence validation of imputed genotyping results	carried out dna sequence validation of imputed genotyping results	Performed the experiments	Investigation|Validation	YES
5571580	28836939	JH	2	provided twin analyses and helped design statistical approaches	provided twin analyses and helped design statistical approaches	Conceived and designed the experiments|Analyzed the data	Formal analysis	YES
5571580	28836939	KK	2	provided primary guidance for all experiments, helped compose the final manuscript and provided funding for the work	provided primary guidance for all experiments, helped compose the final manuscript and provided funding for the work	Performed the experiments|Wrote the paper	Funding acquisition|Investigation|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
5571580	28836939	MK	2	provide analysis strategies and helped interpret statistical information	provide analysis strategies and helped interpret statistical information	Analyzed the data	Formal analysis	YES
5571580	28836939	MM	2	provided help with microbiome analyses and with population stratification approaches	provided help with microbiome analyses and with population stratification approaches	Analyzed the data	Formal analysis	YES
5571580	28836939	RC	2	provided phenotype data on twin and unrelated individuals and assisted in analysis strategy	provided phenotype data on twin and unrelated individuals and assisted in analysis strategy	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5571580	28836939	RK	2	provided critical reading and revision of the manuscript and helped with analysis of microbial data	provided critical reading and revision of the manuscript and helped with analysis of microbial data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Review & Editing	YES
4606086	26495304	All authors	2	read and approved the final paper	read and approved the final paper	-	-	NO
4606086	26495304	Chi-Wei Lin	2	participated in the collection of study material	participated in the collection of study material	Performed the experiments	Investigation	YES
4606086	26495304	Hao-Kuang Wang	2	participated in the collection of study material	participated in the collection of study material	Performed the experiments	Investigation	YES
4606086	26495304	Hung-Hsiang Liou	2	contributed to study conception, participated in its design and coordination, and helped to draft this paper|contributed equally to this work	contributed to study conception, participated in its design and coordination, and helped to draft this paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
4606086	26495304	Hung-Hsiang Liou	2	contributed to study conception, participated in its design and coordination, and helped to draft this paper|contributed equally to this work	contributed equally to this work	-	-	NO
4606086	26495304	I. Chen	2	participated in the collection of study material	participated in the collection of study material	Performed the experiments	Investigation	YES
4606086	26495304	Kuan Min She	2	participated in the collection of study material	participated in the collection of study material	Performed the experiments	Investigation	YES
4606086	26495304	Sheng-Hsiang Lin	2	performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
4606086	26495304	Shih-Yuan Hung	2	contributed to study conception, participated in its design and coordination, and helped to draft this paper	contributed to study conception, participated in its design and coordination, and helped to draft this paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
4606086	26495304	Tsun-Mei Lin	2	contributed to study conception, participated in its design and coordination, and helped to draft this paper|contributed equally to this work	contributed to study conception, participated in its design and coordination, and helped to draft this paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
4606086	26495304	Tsun-Mei Lin	2	contributed to study conception, participated in its design and coordination, and helped to draft this paper|contributed equally to this work	contributed equally to this work	-	-	NO
4606086	26495304	Yau-Sheng Tsai	2	contributed to study conception, participated in its design and coordination, and helped to draft this paper	contributed to study conception, participated in its design and coordination, and helped to draft this paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
4606086	26495304	Yi-Che Lee	2	contributed to study conception, participated in its design and coordination, and helped to draft this paper	contributed to study conception, participated in its design and coordination, and helped to draft this paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
4606086	26495304	Yuan-Yow Chiou	2	contributed to study conception, participated in its design and coordination, and helped to draft this paper	contributed to study conception, participated in its design and coordination, and helped to draft this paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
5748389	29292485	BS	2	were responsible for the study design, statistical analyses, and drafting the manuscript|coordinated the study	were responsible for the study design, statistical analyses, and drafting the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5748389	29292485	BS	2	were responsible for the study design, statistical analyses, and drafting the manuscript|coordinated the study	coordinated the study	-	Project administration	YES
5748389	29292485	JM	2	were responsible for the study design, statistical analyses, and drafting the manuscript	were responsible for the study design, statistical analyses, and drafting the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5748389	29292485	LL	2	was the radiation oncologist responsible for the radiation treatment and drafted the manuscript	was the radiation oncologist responsible for the radiation treatment and drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5748389	29292485	RK	2	were the gynecologic oncologists responsible for the follow-up of the patients|coordinated the study	were the gynecologic oncologists responsible for the follow-up of the patients	-	-	NO
5748389	29292485	RK	2	were the gynecologic oncologists responsible for the follow-up of the patients|coordinated the study	coordinated the study	-	Project administration	YES
5748389	29292485	SV	2	was the nuclear medicine physician responsible for the analyzation of the pet images	was the nuclear medicine physician responsible for the analyzation of the pet images	Analyzed the data	Formal analysis|Visualization	YES
5748389	29292485	TvG	2	were the gynecologic oncologists responsible for the follow-up of the patients	were the gynecologic oncologists responsible for the follow-up of the patients	-	-	NO
5712318	29234338	CO	PLoS52	conceived and designed the research project	conceived and designed the research project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5712318	29234338	H-MZ	PLoS52	performed the experiments and compiled the data sets	performed the experiments and compiled the data sets	Performed the experiments	Data curation|Investigation	YES
5712318	29234338	JP	PLoS52	conceived and designed the research project|analyzed the data	conceived and designed the research project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5712318	29234338	JP	PLoS52	conceived and designed the research project|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5712318	29234338	KC	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5712318	29234338	SW	PLoS52	performed the experiments and compiled the data sets	performed the experiments and compiled the data sets	Performed the experiments	Data curation|Investigation	YES
5712318	29234338	XX	PLoS52	performed the experiments and compiled the data sets	performed the experiments and compiled the data sets	Performed the experiments	Data curation|Investigation	YES
4414279	25923375	AK	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414279	25923375	AK	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414279	25923375	AMB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414279	25923375	AMB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414279	25923375	AMB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414279	25923375	CS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414279	25923375	CS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414279	25923375	CS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414279	25923375	IL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4414279	25923375	IL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4414279	25923375	IL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414279	25923375	JG	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414279	25923375	JG	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414279	25923375	JG	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414279	25923375	TMK	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414279	25923375	TMK	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414279	25923375	TMK	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414279	25923375	TMK	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3260695	22108914	A K Jenum	2	contributed equally to the work	contributed equally to the work	-	-	NO
3260695	22108914	All authors	2	have read and approved the final version	have read and approved the final version	-	-	NO
3260695	22108914	K Morkrid	2	contributed equally to the work	contributed equally to the work	-	-	NO
3260695	22108914	L Sletner	2	prepared the figures	prepared the figures	-	Visualization	YES
3260695	22108914	The authors	2	alone are responsible for the views expressed in the paper	alone are responsible for the views expressed in the paper	-	-	NO
4644132	26567001	BBM	PLoS5	Analyzed the data|Wrote the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4644132	26567001	BBM	PLoS5	Analyzed the data|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4644132	26567001	FJO	PLoS5	Idealized the experiments|Analyzed the data	Idealized the experiments	Conceived and designed the experiments	Conceptualization	YES
4644132	26567001	FJO	PLoS5	Idealized the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4644132	26567001	MAN	PLoS5	Idealized the experiments|Performed the experiments|Analyzed the data	Idealized the experiments	Conceived and designed the experiments	Conceptualization	YES
4644132	26567001	MAN	PLoS5	Idealized the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4644132	26567001	MAN	PLoS5	Idealized the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4644132	26567001	MH	PLoS5	Idealized the experiments|Performed the experiments|Analyzed the data|Wrote the manuscript	Idealized the experiments	Conceived and designed the experiments	Conceptualization	YES
4644132	26567001	MH	PLoS5	Idealized the experiments|Performed the experiments|Analyzed the data|Wrote the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4644132	26567001	MH	PLoS5	Idealized the experiments|Performed the experiments|Analyzed the data|Wrote the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4644132	26567001	MH	PLoS5	Idealized the experiments|Performed the experiments|Analyzed the data|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4644132	26567001	MM	PLoS5	Idealized the experiments|Analyzed the data	Idealized the experiments	Conceived and designed the experiments	Conceptualization	YES
4644132	26567001	MM	PLoS5	Idealized the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4644132	26567001	RSA	PLoS5	Analyzed the data|Wrote the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4644132	26567001	RSA	PLoS5	Analyzed the data|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
1876812	17551584	AH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1876812	17551584	AH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1876812	17551584	AH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1876812	17551584	BS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1876812	17551584	BS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1876812	17551584	CV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1876812	17551584	CV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1876812	17551584	CV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1876812	17551584	CV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1876812	17551584	CV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1876812	17551584	EB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1876812	17551584	HV	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1876812	17551584	HV	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1876812	17551584	HV	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1876812	17551584	NW	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1876812	17551584	NW	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5571589	28836935	DL	2	participated in the cultivation of seedlings and qrt-pcr analysis	participated in the cultivation of seedlings and qrt-pcr analysis	Performed the experiments	Investigation	YES
5571589	28836935	JHH	2	participated in the direction of this study	participated in the direction of this study	-	-	NO
5571589	28836935	LSC	2	designed and directed the study and revised the manuscript	designed and directed the study and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Review & Editing	YES
5571589	28836935	LTY	2	participated in the direction of this study	participated in the direction of this study	-	-	NO
5571589	28836935	WWL	2	carried out most of the experiment, analyzed the data and drafted the manuscript	carried out most of the experiment, analyzed the data and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5762617	29322269	DSL	2	revised the manuscript critically	revised the manuscript critically	Wrote the paper	Writing - Review & Editing	YES
5762617	29322269	GJC	2	provided critical analysis of the study design and revised the manuscript	provided critical analysis of the study design and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5762617	29322269	JCP	2	aided in study design, patient recruitment, and revised the manuscript	aided in study design, patient recruitment, and revised the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
5762617	29322269	JKC	2	revised the manuscript critically	revised the manuscript critically	Wrote the paper	Writing - Review & Editing	YES
5762617	29322269	SYK	2	gathered patients clinical data and revised the manuscript	gathered patients clinical data and revised the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5762617	29322269	YK	2	participated in the study design, performed primary image analysis, and prepared and edited the manuscript	participated in the study design, performed primary image analysis, and prepared and edited the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Investigation|Methodology|Visualization|Writing - Original Draft|Writing - Review & Editing	YES
4414280	25923455	ACR	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414280	25923455	ACR	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414280	25923455	ACR	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414280	25923455	ACR	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414280	25923455	CDB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414280	25923455	CDB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414280	25923455	CDB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414280	25923455	CDB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414280	25923455	CDB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414280	25923455	HVG	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414280	25923455	HVG	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414280	25923455	HVG	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414280	25923455	JH	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414280	25923455	JH	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414280	25923455	JH	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414280	25923455	JLW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414280	25923455	JLW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414280	25923455	JLW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414280	25923455	JLW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414280	25923455	KMH	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414280	25923455	KMH	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414280	25923455	KMH	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414280	25923455	MOLC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414280	25923455	MOLC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414280	25923455	MOLC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414280	25923455	MOLC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414280	25923455	MOLC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414280	25923455	MSH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414280	25923455	MSH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414280	25923455	MSH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414280	25923455	MSH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414280	25923455	MSH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414280	25923455	NA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414280	25923455	NA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414280	25923455	NA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414280	25923455	NA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414280	25923455	TNS	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414280	25923455	TNS	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414280	25923455	TNS	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414280	25923455	WRK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the code used in analysis	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414280	25923455	WRK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the code used in analysis	Performed the experiments	Performed the experiments	Investigation	YES
4414280	25923455	WRK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the code used in analysis	Analyzed the data	Analyzed the data	Formal analysis	YES
4414280	25923455	WRK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the code used in analysis	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414280	25923455	WRK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the code used in analysis	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414280	25923455	WRK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the code used in analysis	Designed the code used in analysis	Conceived and designed the experiments	-	YES
1876813	17551575	JM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1876813	17551575	JM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1876813	17551575	JM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5712320	29234335	KL	2	conceived this study and designed the scientific objectives and prepared the chitosan fragments sample|performed the metabolite profiling data analysis|provided financial support and revised the paper	conceived this study and designed the scientific objectives and prepared the chitosan fragments sample	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
5712320	29234335	KL	2	conceived this study and designed the scientific objectives and prepared the chitosan fragments sample|performed the metabolite profiling data analysis|provided financial support and revised the paper	performed the metabolite profiling data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5712320	29234335	KL	2	conceived this study and designed the scientific objectives and prepared the chitosan fragments sample|performed the metabolite profiling data analysis|provided financial support and revised the paper	provided financial support and revised the paper	Wrote the paper	Funding acquisition|Writing - Review & Editing	YES
5712320	29234335	PL	2	provided financial support and revised the paper	provided financial support and revised the paper	Wrote the paper	Funding acquisition|Writing - Review & Editing	YES
5712320	29234335	RX	2	supervised the project	supervised the project	-	Supervision	YES
5712320	29234335	SL	2	supervised the project	supervised the project	-	Supervision	YES
5712320	29234335	XZ	2	carried out the plant experiments and prepared the manuscript|performed the metabolite profiling data analysis	carried out the plant experiments and prepared the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5712320	29234335	XZ	2	carried out the plant experiments and prepared the manuscript|performed the metabolite profiling data analysis	performed the metabolite profiling data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5770346	29340798	DK	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5770346	29340798	JB	2	performed an additional pathology analysis on the samples obtained from surgery	performed an additional pathology analysis on the samples obtained from surgery	Performed the experiments	Investigation	YES
5770346	29340798	JvD	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5770346	29340798	PET	2	evaluation and analysed the data	evaluation and analysed the data	Analyzed the data	Formal analysis	YES
5770346	29340798	PJ	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5571608	28836963	PG	2	acquired data and performed all the analyses	acquired data and performed all the analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5571608	28836963	RS	2	conceived the idea and designed the project|improved on it	conceived the idea and designed the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5571608	28836963	RS	2	conceived the idea and designed the project|improved on it	improved on it	-	-	NO
4656259	26597959	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4656259	26597959	MM	2	was committed to all the experiments	was committed to all the experiments	-	-	NO
4656259	26597959	NMR	2	wrote the manuscript assisted by all co-authors|designed the study	wrote the manuscript assisted by all co-authors	Wrote the paper	Writing - Original Draft	YES
4656259	26597959	NMR	2	wrote the manuscript assisted by all co-authors|designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
4656259	26597959	PHS	2	on statistical analysis and in the discussion on the interpretation of the data	on statistical analysis and in the discussion on the interpretation of the data	Analyzed the data	Formal analysis	YES
4656259	26597959	SR	2	wrote the manuscript assisted by all co-authors|designed the study	wrote the manuscript assisted by all co-authors	Wrote the paper	Writing - Original Draft	YES
4656259	26597959	SR	2	wrote the manuscript assisted by all co-authors|designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
4414281	25923733	AMOL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414281	25923733	AMOL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414281	25923733	AMOL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414281	25923733	GFDP	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4414281	25923733	JCV	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414281	25923733	JNUY	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414281	25923733	JNUY	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414281	25923733	JNUY	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414281	25923733	KCRM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414281	25923733	LRSA	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414281	25923733	PGB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414281	25923733	PGB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414281	25923733	PGB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414281	25923733	PGB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5712348	29234346	AN	2	designed the study, conducted the experiments, and wrote the manuscript	designed the study, conducted the experiments, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5712348	29234346	CK	2	supervised experiments at all stages and performed critical revisions of the manuscript	supervised experiments at all stages and performed critical revisions of the manuscript	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Review & Editing	YES
5712348	29234346	KK	2	assisted the experimentation and data analysis	assisted the experimentation and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5712348	29234346	KL	2	designed the study, conducted the experiments, and wrote the manuscript	designed the study, conducted the experiments, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5712348	29234346	TA	2	assisted the experimentation and data analysis	assisted the experimentation and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
1876814	17551576	AG	PLoS5	Analyzed the data|Wrote the paper|Analysis and interpretation of laboratory data	Analyzed the data	Analyzed the data	Formal analysis	YES
1876814	17551576	AG	PLoS5	Analyzed the data|Wrote the paper|Analysis and interpretation of laboratory data	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1876814	17551576	AG	PLoS5	Analyzed the data|Wrote the paper|Analysis and interpretation of laboratory data	Analysis and interpretation of laboratory data	Analyzed the data	Formal analysis	YES
1876814	17551576	BG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Analysis and interpretation of laboratory data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1876814	17551576	BG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Analysis and interpretation of laboratory data	Analyzed the data	Analyzed the data	Formal analysis	YES
1876814	17551576	BG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Analysis and interpretation of laboratory data	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1876814	17551576	BG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Analysis and interpretation of laboratory data	Analysis and interpretation of laboratory data	Analyzed the data	Formal analysis	YES
1876814	17551576	CF	PLoS5	Analyzed the data|Analysis and interpretation of laboratory data	Analyzed the data	Analyzed the data	Formal analysis	YES
1876814	17551576	CF	PLoS5	Analyzed the data|Analysis and interpretation of laboratory data	Analysis and interpretation of laboratory data	Analyzed the data	Formal analysis	YES
1876814	17551576	CS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1876814	17551576	ES	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1876814	17551576	FG	PLoS5	Analyzed the data|Analysis and interpretation of laboratory data	Analyzed the data	Analyzed the data	Formal analysis	YES
1876814	17551576	FG	PLoS5	Analyzed the data|Analysis and interpretation of laboratory data	Analysis and interpretation of laboratory data	Analyzed the data	Formal analysis	YES
1876814	17551576	GG	PLoS5	Conceived and designed the experiments|Final approval of the version to be published	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1876814	17551576	GG	PLoS5	Conceived and designed the experiments|Final approval of the version to be published	Final approval of the version to be published	-	-	NO
1876814	17551576	IS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1876814	17551576	RA	PLoS5	Conceived and designed the experiments|Wrote the paper|Final approval of the version to be published	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1876814	17551576	RA	PLoS5	Conceived and designed the experiments|Wrote the paper|Final approval of the version to be published	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1876814	17551576	RA	PLoS5	Conceived and designed the experiments|Wrote the paper|Final approval of the version to be published	Final approval of the version to be published	-	-	NO
1876814	17551576	RM	PLoS5	Analyzed the data|Wrote the paper|Analysis and interpretation of laboratory data	Analyzed the data	Analyzed the data	Formal analysis	YES
1876814	17551576	RM	PLoS5	Analyzed the data|Wrote the paper|Analysis and interpretation of laboratory data	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1876814	17551576	RM	PLoS5	Analyzed the data|Wrote the paper|Analysis and interpretation of laboratory data	Analysis and interpretation of laboratory data	Analyzed the data	Formal analysis	YES
3502551	22734448	ABassini	7	essential contributions to the conception and design of the study protocol; acquisition, analysis and interpretation of data; and involvement in drafting of the manuscript|critical revisions for important intellectual content	essential contributions to the conception and design of the study protocol; acquisition, analysis and interpretation of data; and involvement in drafting of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
3502551	22734448	ABassini	7	essential contributions to the conception and design of the study protocol; acquisition, analysis and interpretation of data; and involvement in drafting of the manuscript|critical revisions for important intellectual content	critical revisions for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
3502551	22734448	ABessa	7	essential contributions to the conception and design of the study protocol; acquisition, analysis and interpretation of data; and involvement in drafting of the manuscript	essential contributions to the conception and design of the study protocol; acquisition, analysis and interpretation of data; and involvement in drafting of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
3502551	22734448	JPSWC	7	critical revisions for important intellectual content	critical revisions for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
3502551	22734448	LCC	7	essential contributions to the conception and design of the study protocol; acquisition, analysis and interpretation of data; and involvement in drafting of the manuscript|critical revisions for important intellectual content	essential contributions to the conception and design of the study protocol; acquisition, analysis and interpretation of data; and involvement in drafting of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
3502551	22734448	LCC	7	essential contributions to the conception and design of the study protocol; acquisition, analysis and interpretation of data; and involvement in drafting of the manuscript|critical revisions for important intellectual content	critical revisions for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
3502551	22734448	LCG	7	essential contributions to the conception and design of the study protocol; acquisition, analysis and interpretation of data; and involvement in drafting of the manuscript	essential contributions to the conception and design of the study protocol; acquisition, analysis and interpretation of data; and involvement in drafting of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
3502551	22734448	RFD	7	essential contributions to the conception and design of the study protocol; acquisition, analysis and interpretation of data; and involvement in drafting of the manuscript	essential contributions to the conception and design of the study protocol; acquisition, analysis and interpretation of data; and involvement in drafting of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
3502551	22734448	RL	7	critical revisions for important intellectual content	critical revisions for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5773462	29349517	AB	2	contributed patients, participated in the design and conception of the study, and helped to draft the manuscript	contributed patients, participated in the design and conception of the study, and helped to draft the manuscript	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Methodology|Resources|Writing - Original Draft	YES
5773462	29349517	ACJ	2	carried out pet studies, calculated the fdg uptake measurements, collaborated in part of the statistical analysis related to the fdg uptake measurements, and participated in the design and conception of the study and in drafting the manuscript	carried out pet studies, calculated the fdg uptake measurements, collaborated in part of the statistical analysis related to the fdg uptake measurements, and participated in the design and conception of the study and in drafting the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5773462	29349517	EMMN	2	participated in carrying out the gene expression microarrays	participated in carrying out the gene expression microarrays	Performed the experiments	Investigation	YES
5773462	29349517	FDG	2	uptake measurements|uptake measurements	uptake measurements	Performed the experiments	Investigation	YES
5773462	29349517	FDG	2	uptake measurements|uptake measurements	uptake measurements	Performed the experiments	Investigation	YES
5773462	29349517	FJFM	2	performed the pathological evaluation of the suitability of the biopsies used for microarray analysis	performed the pathological evaluation of the suitability of the biopsies used for microarray analysis	Performed the experiments	Investigation	YES
5773462	29349517	MS	2	contributed patients to the study and helped to draft the manuscript	contributed patients to the study and helped to draft the manuscript	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Original Draft	YES
5773462	29349517	RGM	2	participated in carrying out the gene expression microarrays, performed microarray statistical analysis, elaborated the genomic signature from microarray data and carried out the related statistical analysis, participated in the design and conception of the study, and helped to draft the manuscript	participated in carrying out the gene expression microarrays, performed microarray statistical analysis, elaborated the genomic signature from microarray data and carried out the related statistical analysis, participated in the design and conception of the study, and helped to draft the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
1876815	17551585	DH	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1876815	17551585	JR	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1876815	17551585	JR	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1876815	17551585	MP	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1876815	17551585	MP	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1876815	17551585	SN	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1876815	17551585	UB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1876815	17551585	UB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1876815	17551585	UB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1876815	17551585	UB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1876815	17551585	UM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5571640	28836962	AJ	2	sampled the tissue probes during the slaughter process|designed the study|carried out the cell culture experiments|performed the statistical and bioinformatics analyses of microarray data	sampled the tissue probes during the slaughter process	-	Data curation	YES
5571640	28836962	AJ	2	sampled the tissue probes during the slaughter process|designed the study|carried out the cell culture experiments|performed the statistical and bioinformatics analyses of microarray data	designed the study	Conceived and designed the experiments	Methodology	YES
5571640	28836962	AJ	2	sampled the tissue probes during the slaughter process|designed the study|carried out the cell culture experiments|performed the statistical and bioinformatics analyses of microarray data	carried out the cell culture experiments	Performed the experiments	Investigation	YES
5571640	28836962	AJ	2	sampled the tissue probes during the slaughter process|designed the study|carried out the cell culture experiments|performed the statistical and bioinformatics analyses of microarray data	performed the statistical and bioinformatics analyses of microarray data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5571640	28836962	EM	2	performed the statistical and bioinformatics analyses of microarray data|critically revised the manuscript	performed the statistical and bioinformatics analyses of microarray data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5571640	28836962	EM	2	performed the statistical and bioinformatics analyses of microarray data|critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5571640	28836962	FH	2	helped in target prediction analysis and created the heat map|critically revised the manuscript	helped in target prediction analysis and created the heat map	Analyzed the data	Formal analysis	YES
5571640	28836962	FH	2	helped in target prediction analysis and created the heat map|critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5571640	28836962	KW	2	sampled the tissue probes during the slaughter process|critically revised the manuscript	sampled the tissue probes during the slaughter process	-	Data curation	YES
5571640	28836962	KW	2	sampled the tissue probes during the slaughter process|critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5571640	28836962	LBA	2	collected and classified the bacteria samples|prepared the bacteria for experimental study	collected and classified the bacteria samples	Performed the experiments	Investigation	YES
5571640	28836962	LBA	2	collected and classified the bacteria samples|prepared the bacteria for experimental study	prepared the bacteria for experimental study	-	-	NO
5571640	28836962	NK	2	collected and classified the bacteria samples|critically revised the manuscript	collected and classified the bacteria samples	Performed the experiments	Investigation	YES
5571640	28836962	NK	2	collected and classified the bacteria samples|critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5571640	28836962	SP	2	designed the study|performed the statistical and bioinformatics analyses of microarray data|critically revised the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5571640	28836962	SP	2	designed the study|performed the statistical and bioinformatics analyses of microarray data|critically revised the manuscript	performed the statistical and bioinformatics analyses of microarray data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5571640	28836962	SP	2	designed the study|performed the statistical and bioinformatics analyses of microarray data|critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4414309	25658745	ALL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414309	25658745	ALL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414309	25658745	ALL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414309	25658745	ALL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414309	25658745	BJC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414309	25658745	BJC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414309	25658745	BJC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414309	25658745	CT	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4414309	25658745	CW	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414309	25658745	CW	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414309	25658745	CW	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414309	25658745	CW	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414309	25658745	LP	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414309	25658745	LP	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414309	25658745	LP	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414309	25658745	SR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414309	25658745	SR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414309	25658745	SR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414309	25658745	SR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414309	25658745	ZR	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4659786	26606918	AB	2	designed experiments and drafted the manuscript	designed experiments and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4659786	26606918	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4659786	26606918	EC	2	displayed cyt1aa in m13 and performed binding experiments	displayed cyt1aa in m13 and performed binding experiments	Performed the experiments	Investigation	YES
4659786	26606918	FP	2	designed ribosome display experiments and provided materials for displaying the toxins in ribosomes	designed ribosome display experiments and provided materials for displaying the toxins in ribosomes	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Methodology|Resources	YES
4659786	26606918	FZN	2	displayed cry3aa and performed binding experiments	displayed cry3aa and performed binding experiments	Performed the experiments	Investigation	YES
4659786	26606918	J. Wiersma	2	for kindly providing the phaberge system	for kindly providing the phaberge system	-	-	NO
4659786	26606918	MS	2	designed experiments and drafted the manuscript	designed experiments and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4659786	26606918	SP	2	constructed vectors for phage display, displayed cry1ac in m13 and all ribosome display experiments and drafted the manuscript	constructed vectors for phage display, displayed cry1ac in m13 and all ribosome display experiments and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4659786	26606918	To Erik	2	for kindly providing the phaberge system	for kindly providing the phaberge system	-	-	NO
4659786	26606918	To Lizbeth Cabrera	2	for technical assistance	for technical assistance	Performed the experiments	Investigation	YES
3506449	23035701	AJW	2	assisted with data collection and data analysis	assisted with data collection and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3506449	23035701	AMG	2	assisted with data collection and data analysis	assisted with data collection and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3506449	23035701	DRW	2	helped drafting the manuscript|assisted with data collection and data analysis	helped drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
3506449	23035701	DRW	2	helped drafting the manuscript|assisted with data collection and data analysis	assisted with data collection and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3506449	23035701	GTM	2	assisted with data collection and data analysis	assisted with data collection and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3506449	23035701	JRH	2	was the primary investigator, supervised all study recruitment and data/specimen analysis|designed study|performed the statistical analysis|supervised the manuscript preparation	was the primary investigator, supervised all study recruitment and data/specimen analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Supervision	YES
3506449	23035701	JRH	2	was the primary investigator, supervised all study recruitment and data/specimen analysis|designed study|performed the statistical analysis|supervised the manuscript preparation	designed study	Conceived and designed the experiments	Methodology	YES
3506449	23035701	JRH	2	was the primary investigator, supervised all study recruitment and data/specimen analysis|designed study|performed the statistical analysis|supervised the manuscript preparation	performed the statistical analysis	Analyzed the data	Formal analysis	YES
3506449	23035701	JRH	2	was the primary investigator, supervised all study recruitment and data/specimen analysis|designed study|performed the statistical analysis|supervised the manuscript preparation	supervised the manuscript preparation	Wrote the paper	Supervision|Writing - Original Draft	YES
3506449	23035701	JRS	2	performed the statistical analysis|helped drafting the manuscript	performed the statistical analysis	Analyzed the data	Formal analysis	YES
3506449	23035701	JRS	2	performed the statistical analysis|helped drafting the manuscript	helped drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
3506449	23035701	MP	2	designed study	designed study	Conceived and designed the experiments	Methodology	YES
3506449	23035701	MSF	2	assisted with data collection and data analysis	assisted with data collection and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3506449	23035701	NSE	2	assisted with data collection and data analysis	assisted with data collection and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3506449	23035701	RJ	2	designed study|helped drafting the manuscript	designed study	Conceived and designed the experiments	Methodology	YES
3506449	23035701	RJ	2	designed study|helped drafting the manuscript	helped drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
3506449	23035701	TCS	2	assisted with data collection and data analysis	assisted with data collection and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3506449	23035701	WPM	2	assisted with data collection and data analysis	assisted with data collection and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5712356	29234345	LS	2	designed the experiments|analyzed the data and wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5712356	29234345	LS	2	designed the experiments|analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5712356	29234345	MS	2	designed the experiments|analyzed the data and wrote the manuscript|supervised this study	designed the experiments	Conceived and designed the experiments	Methodology	YES
5712356	29234345	MS	2	designed the experiments|analyzed the data and wrote the manuscript|supervised this study	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5712356	29234345	MS	2	designed the experiments|analyzed the data and wrote the manuscript|supervised this study	supervised this study	-	Supervision	YES
5712356	29234345	SP	2	designed the experiments|carried out the field and laboratory experiments|analyzed the data and wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5712356	29234345	SP	2	designed the experiments|carried out the field and laboratory experiments|analyzed the data and wrote the manuscript	carried out the field and laboratory experiments	Performed the experiments	Investigation	YES
5712356	29234345	SP	2	designed the experiments|carried out the field and laboratory experiments|analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5712356	29234345	VR	2	carried out the field and laboratory experiments	carried out the field and laboratory experiments	Performed the experiments	Investigation	YES
5778088	29356993	CAP	2	contributed to the study design and data acquisition	contributed to the study design and data acquisition	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources	YES
5778088	29356993	DRM	2	contributed to the study design and data acquisition, data interpretation, and manuscript revision	contributed to the study design and data acquisition, data interpretation, and manuscript revision	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Review & Editing	YES
5778088	29356993	ETH	2	contributed to the data processing and manuscript revision	contributed to the data processing and manuscript revision	Analyzed the data|Wrote the paper	Data curation|Writing - Review & Editing	YES
5778088	29356993	KMB	2	scored the clinical images and contributed to the data interpretation and manuscript revision	scored the clinical images and contributed to the data interpretation and manuscript revision	Analyzed the data|Wrote the paper	Formal analysis|Visualization|Writing - Review & Editing	YES
5778088	29356993	MDW	2	contributed to the data acquisition and manuscript revision	contributed to the data acquisition and manuscript revision	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5574090	28841859	AL	2	performed phenotype assessment, gwas mapping and genotyping	performed phenotype assessment, gwas mapping and genotyping	Performed the experiments	Investigation	YES
5574090	28841859	All authors	2	participated in writing the manuscript and have read and approved the final version	participated in writing the manuscript and have read and approved the final version	Wrote the paper	Writing - Original Draft	YES
5574090	28841859	CD	2	designed the study|drafted the paper	designed the study	Conceived and designed the experiments	Methodology	YES
5574090	28841859	CD	2	designed the study|drafted the paper	drafted the paper	Wrote the paper	Writing - Original Draft	YES
5574090	28841859	DB	2	performed phenotype assessment, gwas mapping and genotyping	performed phenotype assessment, gwas mapping and genotyping	Performed the experiments	Investigation	YES
5574090	28841859	GDS	2	evaluated biopsies of peripheral nerves	evaluated biopsies of peripheral nerves	Performed the experiments	Investigation	YES
5574090	28841859	JRM	2	designed the study|drafted the paper	designed the study	Conceived and designed the experiments	Methodology	YES
5574090	28841859	JRM	2	designed the study|drafted the paper	drafted the paper	Wrote the paper	Writing - Original Draft	YES
5574090	28841859	KJE	2	performed phenotype assessment, gwas mapping and genotyping	performed phenotype assessment, gwas mapping and genotyping	Performed the experiments	Investigation	YES
5574090	28841859	KMM	2	performed phenotype assessment, gwas mapping and genotyping	performed phenotype assessment, gwas mapping and genotyping	Performed the experiments	Investigation	YES
5574090	28841859	TL	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5574090	28841859	VJ	2	performed bioinformatics	performed bioinformatics	Performed the experiments	Formal analysis|Investigation	YES
1876816	17551586	BD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1876816	17551586	BD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1876816	17551586	BD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1876816	17551586	BT	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1876816	17551586	BT	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1876816	17551586	IW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1876816	17551586	KA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1876816	17551586	KA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1876816	17551586	KA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1876816	17551586	KK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1876816	17551586	KK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1876816	17551586	KK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1876816	17551586	KK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1876816	17551586	MA	PLoS5	Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1876816	17551586	MA	PLoS5	Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1876816	17551586	MA	PLoS5	Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1876816	17551586	MA	PLoS5	Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1876816	17551586	OS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1876816	17551586	OS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1876816	17551586	OS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1876816	17551586	OS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1876816	17551586	TO	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1876816	17551586	TO	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1876816	17551586	TO	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1876816	17551586	TO	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414346	25923120	DM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414346	25923120	DM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414346	25923120	GDG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4414346	25923120	RRS	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414346	25923120	RRS	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414346	25923120	VK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414346	25923120	VK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414346	25923120	VK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414346	25923120	VK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414346	25923120	VK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3507661	23013531	ARS	2	were responsible for the study design, coordination of the study, and oversight of data collection and analysis	were responsible for the study design, coordination of the study, and oversight of data collection and analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology|Project administration|Supervision	YES
3507661	23013531	DRK	2	were responsible for the study design, coordination of the study, and oversight of data collection and analysis	were responsible for the study design, coordination of the study, and oversight of data collection and analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology|Project administration|Supervision	YES
3507661	23013531	DSK	2	were responsible for the study design, coordination of the study, and oversight of data collection and analysis	were responsible for the study design, coordination of the study, and oversight of data collection and analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology|Project administration|Supervision	YES
3507661	23013531	RJB	2	assisted in manuscript preparation	assisted in manuscript preparation	Wrote the paper	Writing - Original Draft	YES
3507661	23013531	SF	2	were responsible for the study design, coordination of the study, and oversight of data collection and analysis	were responsible for the study design, coordination of the study, and oversight of data collection and analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology|Project administration|Supervision	YES
4659796	26606919	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4659796	26606919	BC	2	conceived the project and provided the library	conceived the project and provided the library	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceptualization|Resources	YES
4659796	26606919	CSC	2	carried out the pha characterisation	carried out the pha characterisation	Performed the experiments	Investigation	YES
4659796	26606919	PW	2	carried out the microbial analysis, the sequencing and the phylogenetic analysis and draft the script	carried out the microbial analysis, the sequencing and the phylogenetic analysis and draft the script	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4659796	26606919	VBL	2	conceived, supervised the project and contributed to write the script	conceived, supervised the project and contributed to write the script	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Software|Supervision	YES
4659796	26606919	XM	2	carried out the fermenter experiments and helped writing the script	carried out the fermenter experiments and helped writing the script	Performed the experiments|Wrote the paper	Investigation	YES
5712362	29234333	AR	2	edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5712362	29234333	All co-authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5712362	29234333	BA	2	collected dna sample and did wet lab validation	collected dna sample and did wet lab validation	Performed the experiments	Investigation|Validation	YES
5712362	29234333	DeK	2	collected dna sample and did wet lab validation	collected dna sample and did wet lab validation	Performed the experiments	Investigation|Validation	YES
5712362	29234333	DiK	2	conceived the theme of the study|drafted the manuscript	conceived the theme of the study	Conceived and designed the experiments	Conceptualization	YES
5712362	29234333	DiK	2	conceived the theme of the study|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5712362	29234333	GS	2	edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5712362	29234333	MI	2	did the computational analysis and developed database|drafted the manuscript	did the computational analysis and developed database	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Software	YES
5712362	29234333	MI	2	did the computational analysis and developed database|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5712362	29234333	NR	2	collected dna sample and did wet lab validation	collected dna sample and did wet lab validation	Performed the experiments	Investigation|Validation	YES
5712362	29234333	PS	2	edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5712362	29234333	RS	2	edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5712362	29234333	RT	2	conceived the theme of the study|collected dna sample and did wet lab validation|edited the manuscript	conceived the theme of the study	Conceived and designed the experiments	Conceptualization	YES
5712362	29234333	RT	2	conceived the theme of the study|collected dna sample and did wet lab validation|edited the manuscript	collected dna sample and did wet lab validation	Performed the experiments	Investigation|Validation	YES
5712362	29234333	RT	2	conceived the theme of the study|collected dna sample and did wet lab validation|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5712362	29234333	SJ	2	did the computational analysis and developed database|drafted the manuscript	did the computational analysis and developed database	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Software	YES
5712362	29234333	SJ	2	did the computational analysis and developed database|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5712362	29234333	SS	2	collected dna sample and did wet lab validation|drafted the manuscript	collected dna sample and did wet lab validation	Performed the experiments	Investigation|Validation	YES
5712362	29234333	SS	2	collected dna sample and did wet lab validation|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5712362	29234333	UA	2	did the computational analysis and developed database	did the computational analysis and developed database	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Software	YES
5712362	29234333	VA	2	did the computational analysis and developed database	did the computational analysis and developed database	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Software	YES
5576108	28851270	ML	2	made substantial contributions to conception and design	made substantial contributions to conception and design	Conceived and designed the experiments	Conceptualization	YES
5576108	28851270	QK	2	analyzed and interpreted the data	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5576108	28851270	YD	2	made substantial contributions to conception and design|analyzed and interpreted the data|wrote the manuscript	made substantial contributions to conception and design	Conceived and designed the experiments	Conceptualization	YES
5576108	28851270	YD	2	made substantial contributions to conception and design|analyzed and interpreted the data|wrote the manuscript	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5576108	28851270	YD	2	made substantial contributions to conception and design|analyzed and interpreted the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5576108	28851270	YL	2	made substantial contributions to conception and design|participated in the acquisition of data	made substantial contributions to conception and design	Conceived and designed the experiments	Conceptualization	YES
5576108	28851270	YL	2	made substantial contributions to conception and design|participated in the acquisition of data	participated in the acquisition of data	Performed the experiments	Investigation	YES
5576108	28851270	YY	2	made substantial contributions to conception and design|participated in the acquisition of data	made substantial contributions to conception and design	Conceived and designed the experiments	Conceptualization	YES
5576108	28851270	YY	2	made substantial contributions to conception and design|participated in the acquisition of data	participated in the acquisition of data	Performed the experiments	Investigation	YES
5576108	28851270	ZH	2	analyzed and interpreted the data|wrote the manuscript	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5576108	28851270	ZH	2	analyzed and interpreted the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5576108	28851270	ZL	2	made substantial contributions to conception and design	made substantial contributions to conception and design	Conceived and designed the experiments	Conceptualization	YES
5576108	28851270	ZW	2	participated in the acquisition of data	participated in the acquisition of data	Performed the experiments	Investigation	YES
5778091	29356983	AL	PLoS52	wrote the article|developed the methodology|analysed the data	wrote the article	Wrote the paper	Writing - Original Draft	YES
5778091	29356983	AL	PLoS52	wrote the article|developed the methodology|analysed the data	developed the methodology	Performed the experiments	Methodology	YES
5778091	29356983	AL	PLoS52	wrote the article|developed the methodology|analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
5778091	29356983	All authors	PLoS52	contributed to drafting/revising the manuscript and have approved the final content	contributed to drafting/revising the manuscript and have approved the final content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5778091	29356983	All co-authors	PLoS52	have contributed significantly to this manuscript	have contributed significantly to this manuscript	-	-	NO
5778091	29356983	DR	PLoS52	wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
5778091	29356983	DV	PLoS52	wrote the article|analysed the data	wrote the article	Wrote the paper	Writing - Original Draft	YES
5778091	29356983	DV	PLoS52	wrote the article|analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
5778091	29356983	FH	PLoS52	wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
5778091	29356983	GVD	PLoS52	wrote the article|designed the research|developed the methodology|analysed the data	wrote the article	Wrote the paper	Writing - Original Draft	YES
5778091	29356983	GVD	PLoS52	wrote the article|designed the research|developed the methodology|analysed the data	designed the research	Conceived and designed the experiments	Methodology	YES
5778091	29356983	GVD	PLoS52	wrote the article|designed the research|developed the methodology|analysed the data	developed the methodology	Performed the experiments	Methodology	YES
5778091	29356983	GVD	PLoS52	wrote the article|designed the research|developed the methodology|analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
5778091	29356983	HVE	PLoS52	wrote the article|acquired the data|provided the study supervision	wrote the article	Wrote the paper	Writing - Original Draft	YES
5778091	29356983	HVE	PLoS52	wrote the article|acquired the data|provided the study supervision	acquired the data	Performed the experiments	Investigation	YES
5778091	29356983	HVE	PLoS52	wrote the article|acquired the data|provided the study supervision	provided the study supervision	-	Supervision	YES
5778091	29356983	MH	PLoS52	wrote the article|designed the research|developed the methodology|analysed the data	wrote the article	Wrote the paper	Writing - Original Draft	YES
5778091	29356983	MH	PLoS52	wrote the article|designed the research|developed the methodology|analysed the data	designed the research	Conceived and designed the experiments	Methodology	YES
5778091	29356983	MH	PLoS52	wrote the article|designed the research|developed the methodology|analysed the data	developed the methodology	Performed the experiments	Methodology	YES
5778091	29356983	MH	PLoS52	wrote the article|designed the research|developed the methodology|analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
5778091	29356983	OH	PLoS52	wrote the article|designed the research|developed the methodology|acquired the data|analysed the data	wrote the article	Wrote the paper	Writing - Original Draft	YES
5778091	29356983	OH	PLoS52	wrote the article|designed the research|developed the methodology|acquired the data|analysed the data	designed the research	Conceived and designed the experiments	Methodology	YES
5778091	29356983	OH	PLoS52	wrote the article|designed the research|developed the methodology|acquired the data|analysed the data	developed the methodology	Performed the experiments	Methodology	YES
5778091	29356983	OH	PLoS52	wrote the article|designed the research|developed the methodology|acquired the data|analysed the data	acquired the data	Performed the experiments	Investigation	YES
5778091	29356983	OH	PLoS52	wrote the article|designed the research|developed the methodology|acquired the data|analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
5778091	29356983	RC	PLoS52	wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
5778091	29356983	TN	PLoS52	wrote the article|designed the research	wrote the article	Wrote the paper	Writing - Original Draft	YES
5778091	29356983	TN	PLoS52	wrote the article|designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
5778091	29356983	VM	PLoS52	wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
5778091	29356983	WM	PLoS52	wrote the article|designed the research|developed the methodology|acquired the data|analysed the data|provided the study supervision	wrote the article	Wrote the paper	Writing - Original Draft	YES
5778091	29356983	WM	PLoS52	wrote the article|designed the research|developed the methodology|acquired the data|analysed the data|provided the study supervision	designed the research	Conceived and designed the experiments	Methodology	YES
5778091	29356983	WM	PLoS52	wrote the article|designed the research|developed the methodology|acquired the data|analysed the data|provided the study supervision	developed the methodology	Performed the experiments	Methodology	YES
5778091	29356983	WM	PLoS52	wrote the article|designed the research|developed the methodology|acquired the data|analysed the data|provided the study supervision	acquired the data	Performed the experiments	Investigation	YES
5778091	29356983	WM	PLoS52	wrote the article|designed the research|developed the methodology|acquired the data|analysed the data|provided the study supervision	analysed the data	Analyzed the data	Formal analysis	YES
5778091	29356983	WM	PLoS52	wrote the article|designed the research|developed the methodology|acquired the data|analysed the data|provided the study supervision	provided the study supervision	-	Supervision	YES
5778091	29356983	YJ	PLoS52	wrote the article|designed the research|developed the methodology|analysed the data	wrote the article	Wrote the paper	Writing - Original Draft	YES
5778091	29356983	YJ	PLoS52	wrote the article|designed the research|developed the methodology|analysed the data	designed the research	Conceived and designed the experiments	Methodology	YES
5778091	29356983	YJ	PLoS52	wrote the article|designed the research|developed the methodology|analysed the data	developed the methodology	Performed the experiments	Methodology	YES
5778091	29356983	YJ	PLoS52	wrote the article|designed the research|developed the methodology|analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
4414347	25923695	EEP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414347	25923695	EEP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414347	25923695	EEP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414347	25923695	EEP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414347	25923695	EEP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414347	25923695	JLK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414347	25923695	JLK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414347	25923695	JLK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414347	25923695	RJS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414347	25923695	RJS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414347	25923695	RJS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1876817	17551587	BD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1876817	17551587	BD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1876817	17551587	BD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1876817	17551587	CW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1876817	17551587	CW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1876817	17551587	CW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1876817	17551587	DN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1876817	17551587	DN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1876817	17551587	DN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1876817	17551587	DN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1876817	17551587	DS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1876817	17551587	DS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1876817	17551587	DS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1876817	17551587	DT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1876817	17551587	DT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1876817	17551587	DT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1876817	17551587	DT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1876817	17551587	JV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1876817	17551587	JV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1876817	17551587	JV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1876817	17551587	JV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1876817	17551587	JV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1876817	17551587	KL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1876817	17551587	KL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1876817	17551587	KL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1876817	17551587	KL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1876817	17551587	LC	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1876817	17551587	LC	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1876817	17551587	MA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1876817	17551587	MA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1876817	17551587	MA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1876817	17551587	MA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1876817	17551587	MA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1876817	17551587	NS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1876817	17551587	NS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1876817	17551587	NS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1876817	17551587	NS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1876817	17551587	NS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1876817	17551587	PM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1876817	17551587	PM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1876817	17551587	PM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1876817	17551587	TL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1876817	17551587	TL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1876817	17551587	TL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1876817	17551587	TL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1876817	17551587	TT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1876817	17551587	TT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1876817	17551587	TT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1876817	17551587	TT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1876817	17551587	TT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3518828	22958314	BMD	2	provided manuscript direction and edited the manuscript	provided manuscript direction and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
3518828	22958314	JDB	2	designed the manuscript, collected and analyzed study data, wrote, and edited the manuscript	designed the manuscript, collected and analyzed study data, wrote, and edited the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5712366	29234348	HH	2	performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
5712366	29234348	HM	2	performed the statistical analysis|wrote the manuscript	performed the statistical analysis	Analyzed the data	Formal analysis	YES
5712366	29234348	HM	2	performed the statistical analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5712366	29234348	KI	2	performed the bioinformatics analysis	performed the bioinformatics analysis	Performed the experiments	Formal analysis|Investigation	YES
5712366	29234348	KM	2	conceived, planned, and supervised the project|performed the bioinformatics analysis|wrote the manuscript	conceived, planned, and supervised the project	Conceived and designed the experiments	Conceptualization|Supervision	YES
5712366	29234348	KM	2	conceived, planned, and supervised the project|performed the bioinformatics analysis|wrote the manuscript	performed the bioinformatics analysis	Performed the experiments	Formal analysis|Investigation	YES
5712366	29234348	KM	2	conceived, planned, and supervised the project|performed the bioinformatics analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5712366	29234348	KT	2	performed the bioinformatics analysis	performed the bioinformatics analysis	Performed the experiments	Formal analysis|Investigation	YES
5712366	29234348	MS	2	performed the transcriptome analysis	performed the transcriptome analysis	Performed the experiments	Investigation	YES
5712366	29234348	RN	2	conceived, planned, and supervised the project|performed the statistical analysis|wrote the manuscript	conceived, planned, and supervised the project	Conceived and designed the experiments	Conceptualization|Supervision	YES
5712366	29234348	RN	2	conceived, planned, and supervised the project|performed the statistical analysis|wrote the manuscript	performed the statistical analysis	Analyzed the data	Formal analysis	YES
5712366	29234348	RN	2	conceived, planned, and supervised the project|performed the statistical analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5712366	29234348	SE	2	performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
5712366	29234348	SK	2	performed the statistical analysis|wrote the manuscript	performed the statistical analysis	Analyzed the data	Formal analysis	YES
5712366	29234348	SK	2	performed the statistical analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5712366	29234348	TS	2	performed the bioinformatics analysis	performed the bioinformatics analysis	Performed the experiments	Formal analysis|Investigation	YES
5712366	29234348	TY	2	performed the bioinformatics analysis	performed the bioinformatics analysis	Performed the experiments	Formal analysis|Investigation	YES
5712366	29234348	YO	2	performed the transcriptome analysis|wrote the manuscript	performed the transcriptome analysis	Performed the experiments	Investigation	YES
5712366	29234348	YO	2	performed the transcriptome analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5712366	29234348	YU-Y	2	performed the transcriptome analysis	performed the transcriptome analysis	Performed the experiments	Investigation	YES
4666183	26621111	AA	2	contributed to experimental design and discussion	contributed to experimental design and discussion	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4666183	26621111	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4666183	26621111	EG-S	2	carried out most of the experiments and drafted the manuscript	carried out most of the experiments and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4666183	26621111	EM	2	conceived the study, participated in its design, and contributed to the writing of the manuscript	conceived the study, participated in its design, and contributed to the writing of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
4666183	26621111	M. This	2	article does not contain any studies with human participants or animals performed by any of the authors	article does not contain any studies with human participants or animals performed by any of the authors	Performed the experiments	Investigation	YES
4666183	26621111	MT	2	developed several experiments	developed several experiments	-	-	NO
4666183	26621111	MTR	2	helped with the statistical analyses	helped with the statistical analyses	Analyzed the data	Formal analysis	YES
4666183	26621111	RG-P	2	assisted with conception and experimental design	assisted with conception and experimental design	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
5576253	28851277	MK	2	collaborated in the rna seq experiments and initial data analyses	collaborated in the rna seq experiments and initial data analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5576253	28851277	S. All	2	authors participated in the discussion for interpreting the analyzed data	authors participated in the discussion for interpreting the analyzed data	Analyzed the data	Formal analysis	YES
5576253	28851277	YK	2	designed the study|collaborated in the rna seq experiments and initial data analyses	designed the study	Conceived and designed the experiments	Methodology	YES
5576253	28851277	YK	2	designed the study|collaborated in the rna seq experiments and initial data analyses	collaborated in the rna seq experiments and initial data analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5576253	28851277	YS	2	designed the study|collaborated in the rna seq experiments and initial data analyses	designed the study	Conceived and designed the experiments	Methodology	YES
5576253	28851277	YS	2	designed the study|collaborated in the rna seq experiments and initial data analyses	collaborated in the rna seq experiments and initial data analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3524467	22937792	AM	2	conducted all the measurements during two field study for data collection before and after the race	conducted all the measurements during two field study for data collection before and after the race	Performed the experiments	Investigation	YES
3524467	22937792	BE	2	conducted all the measurements during two field study for data collection before and after the race	conducted all the measurements during two field study for data collection before and after the race	Performed the experiments	Investigation	YES
3524467	22937792	BK	2	designed the study and assisted the manuscript preparation|conducted all the measurements during two field study for data collection before and after the race	designed the study and assisted the manuscript preparation	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3524467	22937792	BK	2	designed the study and assisted the manuscript preparation|conducted all the measurements during two field study for data collection before and after the race	conducted all the measurements during two field study for data collection before and after the race	Performed the experiments	Investigation	YES
3524467	22937792	CAR	2	assisted in data analyses, statistical analyses, data interpretation and manuscript preparation	assisted in data analyses, statistical analyses, data interpretation and manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3524467	22937792	CM	2	conducted all the measurements during two field study for data collection before and after the race	conducted all the measurements during two field study for data collection before and after the race	Performed the experiments	Investigation	YES
3524467	22937792	JB	2	conducted all the measurements during two field study for data collection before and after the race	conducted all the measurements during two field study for data collection before and after the race	Performed the experiments	Investigation	YES
3524467	22937792	MM	2	drafted and wrote the manuscript	drafted and wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3524467	22937792	PK	2	conducted all the measurements during two field study for data collection before and after the race	conducted all the measurements during two field study for data collection before and after the race	Performed the experiments	Investigation	YES
3524467	22937792	TR	2	assisted in data analyses, statistical analyses, data interpretation and manuscript preparation	assisted in data analyses, statistical analyses, data interpretation and manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5712368	29234334	EK	PLoS52	conceived and designed the experiments|conducted the experiments|analyzed the data|wrote the manuscript|read and approved the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5712368	29234334	EK	PLoS52	conceived and designed the experiments|conducted the experiments|analyzed the data|wrote the manuscript|read and approved the manuscript	conducted the experiments	Performed the experiments	Investigation	YES
5712368	29234334	EK	PLoS52	conceived and designed the experiments|conducted the experiments|analyzed the data|wrote the manuscript|read and approved the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5712368	29234334	EK	PLoS52	conceived and designed the experiments|conducted the experiments|analyzed the data|wrote the manuscript|read and approved the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5712368	29234334	EK	PLoS52	conceived and designed the experiments|conducted the experiments|analyzed the data|wrote the manuscript|read and approved the manuscript	read and approved the manuscript	-	-	NO
5712368	29234334	PK	PLoS52	conceived and designed the experiments|read and approved the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5712368	29234334	PK	PLoS52	conceived and designed the experiments|read and approved the manuscript	read and approved the manuscript	-	-	NO
5712368	29234334	SM	PLoS52	conceived and designed the experiments|read and approved the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5712368	29234334	SM	PLoS52	conceived and designed the experiments|read and approved the manuscript	read and approved the manuscript	-	-	NO
4414348	25923540	AC	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414348	25923540	AC	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414348	25923540	AH	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414348	25923540	AH	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414348	25923540	AR	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414348	25923540	AR	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414348	25923540	ARJ	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414348	25923540	ARJ	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414348	25923540	DM	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414348	25923540	DM	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414348	25923540	IdlSG	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414348	25923540	IdlSG	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414348	25923540	JAP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414348	25923540	JAP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414348	25923540	JAP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414348	25923540	JAP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414348	25923540	JF	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414348	25923540	JF	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414348	25923540	JKR	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414348	25923540	JKR	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414348	25923540	KN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414348	25923540	KN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414348	25923540	KN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414348	25923540	KN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414348	25923540	KN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414348	25923540	LFLC	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414348	25923540	LFLC	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414348	25923540	MD	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414348	25923540	MD	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414348	25923540	MMan	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414348	25923540	MMan	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414348	25923540	MMar	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414348	25923540	MMar	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414348	25923540	MS	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414348	25923540	MS	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414348	25923540	SB	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414348	25923540	SB	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414348	25923540	SB	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414348	25923540	SM	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414348	25923540	SM	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414348	25923540	SS	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414348	25923540	SS	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414348	25923540	TL	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414348	25923540	TL	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1876818	17551588	DE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1876818	17551588	DE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1876818	17551588	DE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1876818	17551588	DE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1876818	17551588	DE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1876818	17551588	WK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1876818	17551588	WK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1876818	17551588	WK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1876818	17551588	WK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3529676	23237333	AE	2	drafted and revised the manuscript	drafted and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3529676	23237333	JD	2	drafted and revised the manuscript	drafted and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3529676	23237333	KP	2	drafted and revised the manuscript	drafted and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3529676	23237333	KS	2	helped draft the manuscript	helped draft the manuscript	Wrote the paper	Writing - Original Draft	YES
3529676	23237333	PZ	2	conceived of the study and participated in its design and data collection	conceived of the study and participated in its design and data collection	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
3529676	23237333	WS	2	performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
4606133	26495282	Chittibabu Guda	2	conceived of the study, provided overall guidance for this project, interpreted results, suggested improvements, and edited the paper	conceived of the study, provided overall guidance for this project, interpreted results, suggested improvements, and edited the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Supervision|Writing - Review & Editing	YES
4606133	26495282	Ru Shen	2	carried out this work, developed the method, analyzed the results, and drafted the paper	carried out this work, developed the method, analyzed the results, and drafted the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4606133	26495282	Xiaosheng Wang	2	conceived and performed validation of the cancer-type specific distinct subgraph patterns, wrote partial paper, and edited the paper	conceived and performed validation of the cancer-type specific distinct subgraph patterns, wrote partial paper, and edited the paper	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Validation|Writing - Original Draft|Writing - Review & Editing	YES
3341665	22408122	A V Sears	2	verified and collected the data and approved the final version of the manuscript	verified and collected the data and approved the final version of the manuscript	Performed the experiments	Investigation|Validation	YES
3341665	22408122	B R Walker	2	designed the study, interpreted the data and contributed to the writing of the manuscript	designed the study, interpreted the data and contributed to the writing of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3341665	22408122	G D O Lowe	2	carried out the biochemical analyses and edited the manuscript	carried out the biochemical analyses and edited the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
3341665	22408122	I J Deary	2	designed the study, interpreted the data and contributed to the writing of the manuscript	designed the study, interpreted the data and contributed to the writing of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3341665	22408122	J F Price	2	designed and carried out the study and edited the manuscript	designed and carried out the study and edited the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
3341665	22408122	J Labad	2	carried out the statistical analysis, interpreted the data and contributed to writing the manuscript	carried out the statistical analysis, interpreted the data and contributed to writing the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3341665	22408122	M W J Strachan	2	designed and carried out the study and approved the final version of the manuscript	designed and carried out the study and approved the final version of the manuscript	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3341665	22408122	R M Reynolds	2	designed and carried out the study, interpreted the data and wrote the manuscript|is guarantor for the manuscript	designed and carried out the study, interpreted the data and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
3341665	22408122	R M Reynolds	2	designed and carried out the study, interpreted the data and wrote the manuscript|is guarantor for the manuscript	is guarantor for the manuscript	-	-	NO
3341665	22408122	R M Williamson	2	carried out the liver sub-study and edited the manuscript	carried out the liver sub-study and edited the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5712405	29234344	JL	2	provide assistance	provide assistance	-	-	NO
1876819	17551589	AP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1876819	17551589	CE	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1876819	17551589	GA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1876819	17551589	GA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1876819	17551589	GA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1876819	17551589	GA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1876819	17551589	GH	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1876819	17551589	KF	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1876819	17551589	MF	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1876819	17551589	MF	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1876819	17551589	OK	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
3529694	23241341	AP	2	played an important role in manuscript preparation and revisions	played an important role in manuscript preparation and revisions	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3529694	23241341	AS	2	played an important role in manuscript preparation and revisions	played an important role in manuscript preparation and revisions	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3529694	23241341	JL	2	played an important role in manuscript preparation and revisions	played an important role in manuscript preparation and revisions	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3529694	23241341	MS	2	was the primary author of the manuscript	was the primary author of the manuscript	Wrote the paper	Writing - Original Draft	YES
5786599	29374335	BB	2	conceived of the study, participated in its design and coordination, and helped to draft the manuscript	conceived of the study, participated in its design and coordination, and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
5786599	29374335	CK	2	participated in the design of the study	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
5786599	29374335	DE	2	carried out the patient recruitment and helped to draft the manuscript	carried out the patient recruitment and helped to draft the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5786599	29374335	FB	2	participated in the design of the study	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
5786599	29374335	HV	2	conceived of the study, participated in its design and coordination, and helped to draft the manuscript	conceived of the study, participated in its design and coordination, and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
5786599	29374335	JR	2	conducted the renal denervation procedures	conducted the renal denervation procedures	Performed the experiments	Investigation	YES
5786599	29374335	LD	2	carried out the patient recruitment, performed the image analysis and statistical analysis, and drafted the manuscript	carried out the patient recruitment, performed the image analysis and statistical analysis, and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Visualization|Writing - Original Draft	YES
5786599	29374335	LV	2	participated in the design of the study	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
5786599	29374335	PB	2	carried out the patient recruitment	carried out the patient recruitment	Performed the experiments	Investigation	YES
5576322	28851275	AHJW	2	performed smrt sequencing and genome assembly	performed smrt sequencing and genome assembly	Performed the experiments	Investigation	YES
5576322	28851275	AZ	2	edited the assembly and performed gene annotation	edited the assembly and performed gene annotation	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Formal analysis|Investigation|Writing - Review & Editing	YES
5576322	28851275	DCS	2	performed and interpreted optical map alignments	performed and interpreted optical map alignments	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5576322	28851275	GR	2	annotated effector genes	annotated effector genes	-	-	NO
5576322	28851275	IL	2	annotated and analysed tes	annotated and analysed tes	-	-	NO
5576322	28851275	J-FD	2	annotated and performed phylogenetic analyses of sm genes and gene clusters, generated the fungal reporter strain, and performed gene expression analysis and confocal microscopy|wrote and revised the manuscript	annotated and performed phylogenetic analyses of sm genes and gene clusters, generated the fungal reporter strain, and performed gene expression analysis and confocal microscopy	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5576322	28851275	J-FD	2	annotated and performed phylogenetic analyses of sm genes and gene clusters, generated the fungal reporter strain, and performed gene expression analysis and confocal microscopy|wrote and revised the manuscript	wrote and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5576322	28851275	JA	2	annotated and analysed tes	annotated and analysed tes	-	-	NO
5576322	28851275	K-TK	2	annotated p450s and transcription factor genes	annotated p450s and transcription factor genes	-	-	NO
5576322	28851275	MVQ	2	annotated and analysed tes	annotated and analysed tes	-	-	NO
5576322	28851275	NL	2	wrote and revised the manuscript	wrote and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5576322	28851275	RJO	2	wrote and revised the manuscript|conceived and managed the project	wrote and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5576322	28851275	RJO	2	wrote and revised the manuscript|conceived and managed the project	conceived and managed the project	Conceived and designed the experiments	Conceptualization|Project administration	YES
5576322	28851275	SM	2	key genes	key genes	-	-	NO
5576322	28851275	SZ	2	performed and interpreted optical map alignments	performed and interpreted optical map alignments	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5576322	28851275	TEs	2	with genes	with genes	-	-	NO
5576322	28851275	Y-HL	2	annotated p450s and transcription factor genes	annotated p450s and transcription factor genes	-	-	NO
4673079	26646789	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4673079	26646789	BS	2	provided dlc-processing of samples	provided dlc-processing of samples	Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Resources	YES
4673079	26646789	HG	2	conceived of the study, and participated in its design and coordination and helped to draft the manuscript	conceived of the study, and participated in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
4673079	26646789	IB	2	conceived of the study, and participated in its design and coordination and helped to draft the manuscript	conceived of the study, and participated in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
4673079	26646789	NH	2	carried out the microbiological testing and drafted the manuscript	carried out the microbiological testing and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4673079	26646789	RB	2	conceived of the study, and participated in its design and coordination and helped to draft the manuscript	conceived of the study, and participated in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
4673079	26646789	RE	2	conceived of the study, and participated in its design and coordination and helped to draft the manuscript	conceived of the study, and participated in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
4673079	26646789	RK	2	provided dlc-processing of samples	provided dlc-processing of samples	Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Resources	YES
4673079	26646789	SJ	2	carried out the microbiological testing and drafted the manuscript	carried out the microbiological testing and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4414350	25923466	AB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4414350	25923466	BP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4414350	25923466	CAC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4414350	25923466	CAL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414350	25923466	CAL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414350	25923466	CAL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414350	25923466	CAL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414350	25923466	CJH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4414350	25923466	DBB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4414350	25923466	DHT	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4414350	25923466	DMR	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4414350	25923466	DMV	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4414350	25923466	GP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4414350	25923466	HLG	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414350	25923466	HLG	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414350	25923466	HLG	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414350	25923466	HW-R	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4414350	25923466	JL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4414350	25923466	KLC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4414350	25923466	LEW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4414350	25923466	MC-J	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4414350	25923466	MKK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4414350	25923466	MLP	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414350	25923466	MLP	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414350	25923466	MLP	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414350	25923466	MLP	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414350	25923466	MPR	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4414350	25923466	NCN	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4414350	25923466	NS	PLoS5	Organized and quality check on data entry	Organized and quality check on data entry	Analyzed the data	Data curation	YES
4414350	25923466	RP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4414350	25923466	TM	PLoS5	Organized and quality check on data entry	Organized and quality check on data entry	Analyzed the data	Data curation	YES
4414350	25923466	VLG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5712406	29234339	All authors	2	have critically revised this manuscript before submission and agreed to all aspects of the work	have critically revised this manuscript before submission and agreed to all aspects of the work	Wrote the paper	Writing - Review & Editing	YES
5712406	29234339	GL	2	bred and provided the wa-cms and its maintainer line used for this study	bred and provided the wa-cms and its maintainer line used for this study	-	-	NO
5712406	29234339	HX	2	designed the experiment, analyzed the data, and drafted the manuscript	designed the experiment, analyzed the data, and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5712406	29234339	JX	2	conducted most of the experiments and participated in data analyses|also participated in the drafting of the manuscript	conducted most of the experiments and participated in data analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5712406	29234339	JX	2	conducted most of the experiments and participated in data analyses|also participated in the drafting of the manuscript	also participated in the drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
5712406	29234339	LL	2	bred and provided the wa-cms and its maintainer line used for this study|was involved in the design of the experiment and the drafting of the manuscript	bred and provided the wa-cms and its maintainer line used for this study	-	-	NO
5712406	29234339	LL	2	bred and provided the wa-cms and its maintainer line used for this study|was involved in the design of the experiment and the drafting of the manuscript	was involved in the design of the experiment and the drafting of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5712406	29234339	SY	2	participated in the experiments	participated in the experiments	Performed the experiments	Investigation	YES
5712406	29234339	TT	2	conducted most of the experiments and participated in data analyses	conducted most of the experiments and participated in data analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5712406	29234339	XY	2	bred and provided the wa-cms and its maintainer line used for this study	bred and provided the wa-cms and its maintainer line used for this study	-	-	NO
5712406	29234339	YL	2	bred and provided the wa-cms and its maintainer line used for this study	bred and provided the wa-cms and its maintainer line used for this study	-	-	NO
5712406	29234339	ZL	2	participated in the experiments	participated in the experiments	Performed the experiments	Investigation	YES
3536606	23217197	DS	2	designed the testing procedure, collected the data, and discussed the results	designed the testing procedure, collected the data, and discussed the results	Conceived and designed the experiments|Performed the experiments	Investigation	YES
3536606	23217197	JR	2	performed statistical analysis and discussed data	performed statistical analysis and discussed data	Analyzed the data	Formal analysis	YES
3536606	23217197	MK	2	did preliminary statistical procedures and drafted the manuscript	did preliminary statistical procedures and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
1876820	17551590	GL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1876820	17551590	GL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1876820	17551590	GL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1876820	17551590	GM	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1876820	17551590	HK	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1876820	17551590	KL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1876820	17551590	LC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1876820	17551590	ME	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1876820	17551590	MV	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1876820	17551590	MV	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1876820	17551590	OB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1876820	17551590	PJ	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1876820	17551590	TS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1876820	17551590	YG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1876820	17551590	YK	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
3536709	23181739	AM	2	supervised the study design, the implementation of the measurements and the drafting and revising the manuscript	supervised the study design, the implementation of the measurements and the drafting and revising the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
3536709	23181739	EH	2	was responsible for the study design, the execution of the measurements, the statistical analysis and the preparation of the manuscript	was responsible for the study design, the execution of the measurements, the statistical analysis and the preparation of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
3536709	23181739	HK	2	helped in interpretation of data and revised the manuscript	helped in interpretation of data and revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
3536709	23181739	RP	2	participated in the study design and carried out all the blood sampling and analysis	participated in the study design and carried out all the blood sampling and analysis	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5712407	29234331	DG	PLoS52	performed all the experiments and data analysis|wrote the paper	performed all the experiments and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5712407	29234331	DG	PLoS52	performed all the experiments and data analysis|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5712407	29234331	JW	PLoS52	participated in data discussion and manuscript revision	participated in data discussion and manuscript revision	Wrote the paper	Writing - Review & Editing	YES
5712407	29234331	LW	PLoS52	participated in data discussion and manuscript revision	participated in data discussion and manuscript revision	Wrote the paper	Writing - Review & Editing	YES
5712407	29234331	MY	PLoS52	participated in data discussion and manuscript revision	participated in data discussion and manuscript revision	Wrote the paper	Writing - Review & Editing	YES
5712407	29234331	WG	PLoS52	participated in data discussion and manuscript revision	participated in data discussion and manuscript revision	Wrote the paper	Writing - Review & Editing	YES
5712407	29234331	XS	PLoS52	performed all the experiments and data analysis|wrote the paper	performed all the experiments and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5712407	29234331	XS	PLoS52	performed all the experiments and data analysis|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5712407	29234331	XW	PLoS52	conceived and led the research|wrote the paper	conceived and led the research	Conceived and designed the experiments	Conceptualization	YES
5712407	29234331	XW	PLoS52	conceived and led the research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5712407	29234331	ZW	PLoS52	participated in data discussion and manuscript revision	participated in data discussion and manuscript revision	Wrote the paper	Writing - Review & Editing	YES
5789121	29380088	HA	2	wrote the letter together|planed together the curriculum of the above-mentioned fellowship program	wrote the letter together	Wrote the paper	Writing - Original Draft	YES
5789121	29380088	HA	2	wrote the letter together|planed together the curriculum of the above-mentioned fellowship program	planed together the curriculum of the above-mentioned fellowship program	-	-	NO
5789121	29380088	ME	2	wrote the letter together|planed together the curriculum of the above-mentioned fellowship program	wrote the letter together	Wrote the paper	Writing - Original Draft	YES
5789121	29380088	ME	2	wrote the letter together|planed together the curriculum of the above-mentioned fellowship program	planed together the curriculum of the above-mentioned fellowship program	-	-	NO
4414351	25923330	AA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414351	25923330	AA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414351	25923330	AA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414351	25923330	AA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414351	25923330	LN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414351	25923330	LN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414351	25923330	LN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414351	25923330	LN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4675757	26660786	All	2	of the persons involved in this experiments were notified about this study and particiapted with their consent	of the persons involved in this experiments were notified about this study and particiapted with their consent	-	-	NO
4675757	26660786	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4675757	26660786	HYL	2	carried out the studies of identifying new microorganisms and drafted the manuscript	carried out the studies of identifying new microorganisms and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4675757	26660786	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
1885212	17551592	EQ	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1885212	17551592	EQ	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1885212	17551592	IA	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1885212	17551592	IA	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1885212	17551592	IA	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1885212	17551592	IA	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1885212	17551592	JC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1885212	17551592	JC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1885212	17551592	JC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5796928	29396705	AKB	2	contributed to drafting the manuscript	contributed to drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
5796928	29396705	All authors	2	revised and approved the manuscript	revised and approved the manuscript	Wrote the paper	Writing - Review & Editing	YES
5796928	29396705	JSM	2	contributed with the phantom design and printing|performed the phantom experiments|performed the data acquisition, data analysis, and calculations|contributed to drafting the manuscript	contributed with the phantom design and printing	Conceived and designed the experiments	-	YES
5796928	29396705	JSM	2	contributed with the phantom design and printing|performed the phantom experiments|performed the data acquisition, data analysis, and calculations|contributed to drafting the manuscript	performed the phantom experiments	Performed the experiments	Investigation	YES
5796928	29396705	JSM	2	contributed with the phantom design and printing|performed the phantom experiments|performed the data acquisition, data analysis, and calculations|contributed to drafting the manuscript	performed the data acquisition, data analysis, and calculations	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5796928	29396705	JSM	2	contributed with the phantom design and printing|performed the phantom experiments|performed the data acquisition, data analysis, and calculations|contributed to drafting the manuscript	contributed to drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
5796928	29396705	JTG	2	contributed with the phantom design and printing|performed the phantom experiments|performed the data acquisition, data analysis, and calculations|contributed to drafting the manuscript	contributed with the phantom design and printing	Conceived and designed the experiments	-	YES
5796928	29396705	JTG	2	contributed with the phantom design and printing|performed the phantom experiments|performed the data acquisition, data analysis, and calculations|contributed to drafting the manuscript	performed the phantom experiments	Performed the experiments	Investigation	YES
5796928	29396705	JTG	2	contributed with the phantom design and printing|performed the phantom experiments|performed the data acquisition, data analysis, and calculations|contributed to drafting the manuscript	performed the data acquisition, data analysis, and calculations	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5796928	29396705	JTG	2	contributed with the phantom design and printing|performed the phantom experiments|performed the data acquisition, data analysis, and calculations|contributed to drafting the manuscript	contributed to drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
5796928	29396705	ML	2	performed the data acquisition, data analysis, and calculations|contributed to drafting the manuscript	performed the data acquisition, data analysis, and calculations	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5796928	29396705	ML	2	performed the data acquisition, data analysis, and calculations|contributed to drafting the manuscript	contributed to drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
5796928	29396705	SS	2	performed the phantom experiments	performed the phantom experiments	Performed the experiments	Investigation	YES
5576338	28851267	AH	2	conceptualized the study and its design, performed experiments, analyzed data, interpreted results, drafted, edited and revised the manuscript	conceptualized the study and its design, performed experiments, analyzed data, interpreted results, drafted, edited and revised the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5576338	28851267	AWH	2	performed experiments, interpreted results, prepared figures, edited and revised the manuscript	performed experiments, interpreted results, prepared figures, edited and revised the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Visualization|Writing - Original Draft|Writing - Review & Editing	YES
5576338	28851267	DLE	2	interpreted results, prepared figures, edited and revised the manuscript	interpreted results, prepared figures, edited and revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Visualization|Writing - Original Draft|Writing - Review & Editing	YES
5576338	28851267	JUR	2	interpreted results and conceptualized the study	interpreted results and conceptualized the study	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
5576338	28851267	MMC	2	analyzed data, interpreted results, prepared figures and drafted the manuscript	analyzed data, interpreted results, prepared figures and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Visualization|Writing - Original Draft	YES
5576338	28851267	NMR	2	analyzed data, interpreted results and prepared figures	analyzed data, interpreted results and prepared figures	Analyzed the data	Formal analysis|Visualization	YES
5576338	28851267	PK	2	interpreted results, edited and revised the manuscript	interpreted results, edited and revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5576338	28851267	SPR	2	interpreted results and conceptualized the study	interpreted results and conceptualized the study	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
5576338	28851267	VN	2	conceptualized the study and its design, interpreted results, edited and revised the manuscript	conceptualized the study and its design, interpreted results, edited and revised the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Review & Editing	YES
5576338	28851267	YD	2	performed experiments and interpreted results	performed experiments and interpreted results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5576338	28851267	ZA	2	analyzed data, interpreted results, prepared figures, drafted, edited and revised the manuscript	analyzed data, interpreted results, prepared figures, drafted, edited and revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Visualization|Writing - Original Draft|Writing - Review & Editing	YES
5576338	28851267	ZL	2	analyzed data, interpreted results, prepared figures and drafted the manuscript	analyzed data, interpreted results, prepared figures and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Visualization|Writing - Original Draft	YES
5712408	29234340	BB	2	designed the study|contributed to sample harvest and data analysis|improved it and all authors revised it	designed the study	Conceived and designed the experiments	Methodology	YES
5712408	29234340	BB	2	designed the study|contributed to sample harvest and data analysis|improved it and all authors revised it	contributed to sample harvest and data analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5712408	29234340	BB	2	designed the study|contributed to sample harvest and data analysis|improved it and all authors revised it	improved it and all authors revised it	Wrote the paper	Writing - Review & Editing	YES
5712408	29234340	CC	2	contributed to starch and secondary metabolite analysis	contributed to starch and secondary metabolite analysis	-	-	NO
5712408	29234340	CL	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5712408	29234340	HE	2	designed the study|contributed to sample harvest and data analysis	designed the study	Conceived and designed the experiments	Methodology	YES
5712408	29234340	HE	2	designed the study|contributed to sample harvest and data analysis	contributed to sample harvest and data analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5712408	29234340	J-CB	2	designed the study|contributed to sample harvest and data analysis|improved it and all authors revised it	designed the study	Conceived and designed the experiments	Methodology	YES
5712408	29234340	J-CB	2	designed the study|contributed to sample harvest and data analysis|improved it and all authors revised it	contributed to sample harvest and data analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5712408	29234340	J-CB	2	designed the study|contributed to sample harvest and data analysis|improved it and all authors revised it	improved it and all authors revised it	Wrote the paper	Writing - Review & Editing	YES
5712408	29234340	J-CP	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5712408	29234340	LT	2	designed the study|contributed to sample harvest and data analysis|contributed to starch and secondary metabolite analysis|contributed to starch and sugar content analysis|wrote the first draft of the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5712408	29234340	LT	2	designed the study|contributed to sample harvest and data analysis|contributed to starch and secondary metabolite analysis|contributed to starch and sugar content analysis|wrote the first draft of the manuscript	contributed to sample harvest and data analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5712408	29234340	LT	2	designed the study|contributed to sample harvest and data analysis|contributed to starch and secondary metabolite analysis|contributed to starch and sugar content analysis|wrote the first draft of the manuscript	contributed to starch and secondary metabolite analysis	-	-	NO
5712408	29234340	LT	2	designed the study|contributed to sample harvest and data analysis|contributed to starch and secondary metabolite analysis|contributed to starch and sugar content analysis|wrote the first draft of the manuscript	contributed to starch and sugar content analysis	-	-	NO
5712408	29234340	LT	2	designed the study|contributed to sample harvest and data analysis|contributed to starch and secondary metabolite analysis|contributed to starch and sugar content analysis|wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
5712408	29234340	LU	2	helped with interpretation of chlorophyll fluorescence data	helped with interpretation of chlorophyll fluorescence data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5712408	29234340	SD	2	contributed to starch and sugar content analysis	contributed to starch and sugar content analysis	-	-	NO
4414352	25923705	BV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Reviewed, revised, and approved manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414352	25923705	BV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Reviewed, revised, and approved manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4414352	25923705	BV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Reviewed, revised, and approved manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4414352	25923705	BV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Reviewed, revised, and approved manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414352	25923705	BV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Reviewed, revised, and approved manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414352	25923705	BV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Reviewed, revised, and approved manuscript	Reviewed, revised, and approved manuscript	Wrote the paper	Writing - Review & Editing	YES
4414352	25923705	EOC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Reviewed, revised, and approved manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4414352	25923705	EOC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Reviewed, revised, and approved manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414352	25923705	EOC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Reviewed, revised, and approved manuscript	Reviewed, revised, and approved manuscript	Wrote the paper	Writing - Review & Editing	YES
4414352	25923705	GDK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Reviewed, revised, and approved manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414352	25923705	GDK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Reviewed, revised, and approved manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4414352	25923705	GDK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Reviewed, revised, and approved manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4414352	25923705	GDK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Reviewed, revised, and approved manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414352	25923705	GDK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Reviewed, revised, and approved manuscript	Reviewed, revised, and approved manuscript	Wrote the paper	Writing - Review & Editing	YES
4414352	25923705	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Reviewed, revised, and approved manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414352	25923705	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Reviewed, revised, and approved manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4414352	25923705	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Reviewed, revised, and approved manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4414352	25923705	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Reviewed, revised, and approved manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414352	25923705	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Reviewed, revised, and approved manuscript	Reviewed, revised, and approved manuscript	Wrote the paper	Writing - Review & Editing	YES
4414352	25923705	JMK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Reviewed, revised, and approved manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414352	25923705	JMK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Reviewed, revised, and approved manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414352	25923705	JMK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Reviewed, revised, and approved manuscript	Reviewed, revised, and approved manuscript	Wrote the paper	Writing - Review & Editing	YES
4414352	25923705	VMT	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Reviewed, revised, and approved manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4414352	25923705	VMT	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Reviewed, revised, and approved manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414352	25923705	VMT	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Reviewed, revised, and approved manuscript	Reviewed, revised, and approved manuscript	Wrote the paper	Writing - Review & Editing	YES
4414352	25923705	VS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Reviewed, revised, and approved manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414352	25923705	VS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Reviewed, revised, and approved manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414352	25923705	VS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Reviewed, revised, and approved manuscript	Reviewed, revised, and approved manuscript	Wrote the paper	Writing - Review & Editing	YES
3538552	23281794	RBK	2	incorporated recommendations into a final draft which was then reviewed, approved, and adopted as the official position of the issn by the research committee	incorporated recommendations into a final draft which was then reviewed, approved, and adopted as the official position of the issn by the research committee	Wrote the paper	Writing - Original Draft	YES
4606138	26495307	Klaus Kratochwill	2	contributed equally to this work	contributed equally to this work	-	-	NO
4606138	26495307	Thorsten O. Bender	2	contributed equally to this work	contributed equally to this work	-	-	NO
5799087	29404708	AB	2	contributed to the collection of the clinical data	contributed to the collection of the clinical data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5799087	29404708	ALS	2	ascertained the clinical question for the pet investigations and contributed to the collection of the clinical data	ascertained the clinical question for the pet investigations and contributed to the collection of the clinical data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5799087	29404708	AS	2	the method of the eeg conducted anesthesia for this setting	the method of the eeg conducted anesthesia for this setting	Performed the experiments	Investigation	YES
5799087	29404708	All authors	2	reviewed and approved the final manuscript	reviewed and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5799087	29404708	BS	2	the method of the eeg conducted anesthesia for this setting	the method of the eeg conducted anesthesia for this setting	Performed the experiments	Investigation	YES
5799087	29404708	FB	2	assured the infrastructure required for the study	assured the infrastructure required for the study	-	-	NO
5799087	29404708	FW	2	contributed to the data analysis	contributed to the data analysis	Analyzed the data	Formal analysis	YES
5799087	29404708	GB	2	was involved in performing the pet studies, supervised the retrospective data analysis, and contributed to the writing of the manuscript	was involved in performing the pet studies, supervised the retrospective data analysis, and contributed to the writing of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Supervision|Writing - Original Draft	YES
5799087	29404708	LG	2	assured the infrastructure required for the study	assured the infrastructure required for the study	-	-	NO
5799087	29404708	MD	2	contributed to the collection of the clinical data	contributed to the collection of the clinical data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5799087	29404708	MF	2	contributed to the collection of the clinical data	contributed to the collection of the clinical data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5799087	29404708	MM	2	performed the retrospective data analysis and contributed to the writing of the manuscript	performed the retrospective data analysis and contributed to the writing of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5799087	29404708	TL	2	assured the infrastructure required for the study	assured the infrastructure required for the study	-	-	NO
1885213	17565367	CH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1885213	17565367	CH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1885213	17565367	CH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1885213	17565367	CH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1885213	17565367	CH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1885213	17565367	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1885213	17565367	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1885213	17565367	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1885213	17565367	MC	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1885213	17565367	MC	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1885213	17565367	NA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1885213	17565367	NA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1885213	17565367	NA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1885213	17565367	NA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1885213	17565367	RT	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1885213	17565367	RT	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4688280	26695948	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4688280	26695948	HH	2	participated in the design this study, data analysis, interpretation of results and drafting of the manuscript	participated in the design this study, data analysis, interpretation of results and drafting of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4688280	26695948	HK	2	involved in the data analysis and interpreted the results	involved in the data analysis and interpreted the results	Analyzed the data	Formal analysis	YES
4688280	26695948	IK	2	involved in the data analysis and interpreted the results	involved in the data analysis and interpreted the results	Analyzed the data	Formal analysis	YES
4688280	26695948	JW	2	participated in the experimental procedures of this study and drafting of the manuscript	participated in the experimental procedures of this study and drafting of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4688280	26695948	KT	2	involved in the data analysis and interpreted the results	involved in the data analysis and interpreted the results	Analyzed the data	Formal analysis	YES
4688280	26695948	KY	2	participated in the experimental procedures of this study and drafting of the manuscript	participated in the experimental procedures of this study and drafting of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4688280	26695948	MA	2	participated in the experimental procedures of this study and drafting of the manuscript	participated in the experimental procedures of this study and drafting of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4688280	26695948	RK	2	involved in the data analysis and interpreted the results	involved in the data analysis and interpreted the results	Analyzed the data	Formal analysis	YES
4688280	26695948	TM	2	participated in the experimental procedures of this study and drafting of the manuscript|involved in the data analysis and interpreted the results	participated in the experimental procedures of this study and drafting of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4688280	26695948	TM	2	participated in the experimental procedures of this study and drafting of the manuscript|involved in the data analysis and interpreted the results	involved in the data analysis and interpreted the results	Analyzed the data	Formal analysis	YES
3400040	22660026	All authors	2	accept public responsibility for the content of the paper and confirm that they meet the icjme conditions for authorship, namely that they conceived and planned the work that led to the article or played an important role in interpreting the results, wrote the paper and/or made substantive suggestions for revision and approved the final version of the manuscript	accept public responsibility for the content of the paper and confirm that they meet the icjme conditions for authorship, namely that they conceived and planned the work that led to the article or played an important role in interpreting the results, wrote the paper and/or made substantive suggestions for revision and approved the final version of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
3542109	23153110	AWK	2	helped extensively with data collection	helped extensively with data collection	Performed the experiments	Investigation	YES
3542109	23153110	DDT	2	carried out subject recruitment, data collection, exercise training, immunoassays, and assisted with manuscript preparation	carried out subject recruitment, data collection, exercise training, immunoassays, and assisted with manuscript preparation	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3542109	23153110	EGW	2	helped extensively with data collection	helped extensively with data collection	Performed the experiments	Investigation	YES
3542109	23153110	JSK	2	provided assay support, and insight into drafting the study design and manuscript	provided assay support, and insight into drafting the study design and manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
3542109	23153110	LBP	2	provided assay support, and insight into drafting the study design and manuscript	provided assay support, and insight into drafting the study design and manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
3542109	23153110	MJO	2	conceived and designed the study, secured funding for the project, provided oversight of data collection, analysis, biochemical assays, and manuscript preparation	conceived and designed the study, secured funding for the project, provided oversight of data collection, analysis, biochemical assays, and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Funding acquisition|Investigation|Methodology|Resources|Supervision|Writing - Original Draft	YES
3542109	23153110	WKM	2	carried out data collection, participant recruitment, exercise training, laboratory testing, and manuscript preparation	carried out data collection, participant recruitment, exercise training, laboratory testing, and manuscript preparation	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5712412	29234343	All authors	2	contributed critically to revision	contributed critically to revision	Wrote the paper	Writing - Review & Editing	YES
5712412	29234343	CX	2	formulated the original idea and developed methodology	formulated the original idea and developed methodology	Conceived and designed the experiments|Performed the experiments	Conceptualization|Methodology	YES
5712412	29234343	FY	2	performed statistical analysis	performed statistical analysis	Analyzed the data	Formal analysis	YES
5712412	29234343	JS	2	performed sample processing|performed statistical analysis	performed sample processing	Performed the experiments	Data curation|Investigation	YES
5712412	29234343	JS	2	performed sample processing|performed statistical analysis	performed statistical analysis	Analyzed the data	Formal analysis	YES
5712412	29234343	YZ	2	wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
4414356	25922949	AC	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414356	25922949	AC	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414356	25922949	APS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4414356	25922949	BR	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4414356	25922949	BR	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4414356	25922949	BR	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414356	25922949	CJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414356	25922949	CJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414356	25922949	CJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414356	25922949	GV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414356	25922949	GV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414356	25922949	GV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414356	25922949	GV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414356	25922949	MC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4414356	25922949	RB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414356	25922949	RB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414356	25922949	RB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414356	25922949	SB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414356	25922949	SB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414356	25922949	SB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414356	25922949	SB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414356	25922949	TC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414356	25922949	TC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414356	25922949	TC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414356	25922949	TC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414356	25922949	VP	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414356	25922949	VP	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4688282	26695947	ABB	PLoS52	have designed the work|analysed the data|reviewed the manuscript and made very important scientific contributions	have designed the work	Conceived and designed the experiments	-	YES
4688282	26695947	ABB	PLoS52	have designed the work|analysed the data|reviewed the manuscript and made very important scientific contributions	analysed the data	Analyzed the data	Formal analysis	YES
4688282	26695947	ABB	PLoS52	have designed the work|analysed the data|reviewed the manuscript and made very important scientific contributions	reviewed the manuscript and made very important scientific contributions	Wrote the paper	Writing - Review & Editing	YES
4688282	26695947	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4688282	26695947	GL	PLoS52	analysed the data|reviewed the manuscript and made very important scientific contributions	analysed the data	Analyzed the data	Formal analysis	YES
4688282	26695947	GL	PLoS52	analysed the data|reviewed the manuscript and made very important scientific contributions	reviewed the manuscript and made very important scientific contributions	Wrote the paper	Writing - Review & Editing	YES
4688282	26695947	RB	PLoS52	have designed the work|carried out the experiment|analysed the data|wrote the manuscript|reviewed the manuscript and made very important scientific contributions	have designed the work	Conceived and designed the experiments	-	YES
4688282	26695947	RB	PLoS52	have designed the work|carried out the experiment|analysed the data|wrote the manuscript|reviewed the manuscript and made very important scientific contributions	carried out the experiment	Performed the experiments	Investigation	YES
4688282	26695947	RB	PLoS52	have designed the work|carried out the experiment|analysed the data|wrote the manuscript|reviewed the manuscript and made very important scientific contributions	analysed the data	Analyzed the data	Formal analysis	YES
4688282	26695947	RB	PLoS52	have designed the work|carried out the experiment|analysed the data|wrote the manuscript|reviewed the manuscript and made very important scientific contributions	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4688282	26695947	RB	PLoS52	have designed the work|carried out the experiment|analysed the data|wrote the manuscript|reviewed the manuscript and made very important scientific contributions	reviewed the manuscript and made very important scientific contributions	Wrote the paper	Writing - Review & Editing	YES
4688282	26695947	XH	PLoS52	have designed the work|carried out the experiment|analysed the data|reviewed the manuscript and made very important scientific contributions	have designed the work	Conceived and designed the experiments	-	YES
4688282	26695947	XH	PLoS52	have designed the work|carried out the experiment|analysed the data|reviewed the manuscript and made very important scientific contributions	carried out the experiment	Performed the experiments	Investigation	YES
4688282	26695947	XH	PLoS52	have designed the work|carried out the experiment|analysed the data|reviewed the manuscript and made very important scientific contributions	analysed the data	Analyzed the data	Formal analysis	YES
4688282	26695947	XH	PLoS52	have designed the work|carried out the experiment|analysed the data|reviewed the manuscript and made very important scientific contributions	reviewed the manuscript and made very important scientific contributions	Wrote the paper	Writing - Review & Editing	YES
3543170	23259853	DMC	2	conducted the exercise training, supplement administration, sample collection and the draft of the manuscript	conducted the exercise training, supplement administration, sample collection and the draft of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3543170	23259853	EDA	2	performed laboratory testing, statistical analysis, and contributed to the draft of the manuscript	performed laboratory testing, statistical analysis, and contributed to the draft of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3543170	23259853	FV	2	performed laboratory testing, statistical analysis, and contributed to the draft of the manuscript	performed laboratory testing, statistical analysis, and contributed to the draft of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3543170	23259853	JLFV	2	performed laboratory testing, statistical analysis, and contributed to the draft of the manuscript	performed laboratory testing, statistical analysis, and contributed to the draft of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3543170	23259853	LMT	2	conducted the exercise training, supplement administration, sample collection and the draft of the manuscript	conducted the exercise training, supplement administration, sample collection and the draft of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3543170	23259853	MC	2	have idealized the study and are responsible for the final form of the manuscript|conducted the exercise training, supplement administration, sample collection and the draft of the manuscript	have idealized the study and are responsible for the final form of the manuscript	Conceived and designed the experiments	Conceptualization	YES
3543170	23259853	MC	2	have idealized the study and are responsible for the final form of the manuscript|conducted the exercise training, supplement administration, sample collection and the draft of the manuscript	conducted the exercise training, supplement administration, sample collection and the draft of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3543170	23259853	SP	2	have idealized the study and are responsible for the final form of the manuscript|performed laboratory testing, statistical analysis, and contributed to the draft of the manuscript	have idealized the study and are responsible for the final form of the manuscript	Conceived and designed the experiments	Conceptualization	YES
3543170	23259853	SP	2	have idealized the study and are responsible for the final form of the manuscript|performed laboratory testing, statistical analysis, and contributed to the draft of the manuscript	performed laboratory testing, statistical analysis, and contributed to the draft of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3543170	23259853	SPTD	2	conducted the exercise training, supplement administration, sample collection and the draft of the manuscript	conducted the exercise training, supplement administration, sample collection and the draft of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3494865	23034782	B Delemer	2	were involved in the study design, data interpretation, drafting, and reviewing the manuscript	were involved in the study design, data interpretation, drafting, and reviewing the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
3494865	23034782	F Landron	2	coordinated the study and was involved in the data interpretation, drafting, and reviewing the manuscript	coordinated the study and was involved in the data interpretation, drafting, and reviewing the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Project administration|Writing - Original Draft|Writing - Review & Editing	YES
3494865	23034782	P Aubert	2	were involved in the study design, data interpretation, and reviewing the manuscript	were involved in the study design, data interpretation, and reviewing the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
3494865	23034782	P Nys	2	were involved in the study design, data interpretation, and reviewing the manuscript	were involved in the study design, data interpretation, and reviewing the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
3494865	23034782	S Bouee	2	were involved in the study design, data interpretation, drafting, and reviewing the manuscript	were involved in the study design, data interpretation, drafting, and reviewing the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
1885214	17565368	AB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1885214	17565368	BA	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1885214	17565368	BC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1885214	17565368	FR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1885214	17565368	FR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1885214	17565368	FR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1885214	17565368	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1885214	17565368	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1885214	17565368	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1885214	17565368	JW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1885214	17565368	JW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1885214	17565368	JW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1885214	17565368	LD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1885214	17565368	LD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1885214	17565368	LD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1885214	17565368	LD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1885214	17565368	MR	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1885214	17565368	PC	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1885214	17565368	PC	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1885214	17565368	RL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1885214	17565368	RL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1885214	17565368	SB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1885214	17565368	SH	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1885214	17565368	SH	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5577687	28854875	MAJ	2	designed the study and wrote the manuscript	designed the study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5577687	28854875	MB	2	contributed to data analyses	contributed to data analyses	Analyzed the data	Formal analysis	YES
5577687	28854875	MR	2	designed the study and wrote the manuscript|contributed to data analyses	designed the study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5577687	28854875	MR	2	designed the study and wrote the manuscript|contributed to data analyses	contributed to data analyses	Analyzed the data	Formal analysis	YES
5577687	28854875	NWGC	2	designed the study and wrote the manuscript|contributed to data analyses	designed the study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5577687	28854875	NWGC	2	designed the study and wrote the manuscript|contributed to data analyses	contributed to data analyses	Analyzed the data	Formal analysis	YES
5577687	28854875	SB	2	contributed to data analyses	contributed to data analyses	Analyzed the data	Formal analysis	YES
5712414	29234347	FC	2	designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
5712414	29234347	HC	2	did experiment and analyzed the data|wrote the manuscript	did experiment and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5712414	29234347	HC	2	did experiment and analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5712414	29234347	JS	2	did experiment and analyzed the data	did experiment and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5712414	29234347	JX	2	did experiment and analyzed the data	did experiment and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5712414	29234347	LW	2	did experiment and analyzed the data	did experiment and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5712414	29234347	MAN	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5712414	29234347	MLN	2	did experiment and analyzed the data	did experiment and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5712414	29234347	QK	2	designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
5712414	29234347	YH	2	designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
5712414	29234347	ZB	2	designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
4414357	25923789	AF	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414357	25923789	AI	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414357	25923789	BG	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414357	25923789	CC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414357	25923789	CC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414357	25923789	CC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414357	25923789	JW	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414357	25923789	JW	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414357	25923789	LZ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414357	25923789	MFGZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414357	25923789	MFGZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414357	25923789	MFGZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414357	25923789	RC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414357	25923789	TJ	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5801140	29411169	CL	2	performed the analysis	performed the analysis	Performed the experiments	Investigation	YES
5801140	29411169	MH	2	performed the analysis	performed the analysis	Performed the experiments	Investigation	YES
5801140	29411169	MSJ	2	aided in drafting the manuscript and revised it critically for important intellectual content	aided in drafting the manuscript and revised it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5801140	29411169	NN	2	performed the analysis	performed the analysis	Performed the experiments	Investigation	YES
5801140	29411169	RAW	2	designed the study, wrote the manuscript, and researched the data|performed the analysis	designed the study, wrote the manuscript, and researched the data	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5801140	29411169	RAW	2	designed the study, wrote the manuscript, and researched the data|performed the analysis	performed the analysis	Performed the experiments	Investigation	YES
5801140	29411169	SR	2	aided in drafting the manuscript and revised it critically for important intellectual content	aided in drafting the manuscript and revised it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5801140	29411169	TH	2	designed the study, wrote the manuscript, and researched the data|aided in drafting the manuscript and revised it critically for important intellectual content	designed the study, wrote the manuscript, and researched the data	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5801140	29411169	TH	2	designed the study, wrote the manuscript, and researched the data|aided in drafting the manuscript and revised it critically for important intellectual content	aided in drafting the manuscript and revised it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5801140	29411169	XC	2	designed the study, wrote the manuscript, and researched the data|performed the analysis	designed the study, wrote the manuscript, and researched the data	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5801140	29411169	XC	2	designed the study, wrote the manuscript, and researched the data|performed the analysis	performed the analysis	Performed the experiments	Investigation	YES
3545722	23270306	JD	2	drafted and revised the manuscript	drafted and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3545722	23270306	JK	2	reviewed the bone density data and confirmed its validity as well as general conclusions drawn from it	reviewed the bone density data and confirmed its validity as well as general conclusions drawn from it	-	-	NO
3545722	23270306	KP	2	drafted and revised the manuscript	drafted and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3545722	23270306	PZ	2	drafted and revised the manuscript|conceived of the study and participated in its design and data collection	drafted and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3545722	23270306	PZ	2	drafted and revised the manuscript|conceived of the study and participated in its design and data collection	conceived of the study and participated in its design and data collection	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
5712419	29234341	AB	7	paper writing	paper writing	Wrote the paper	-	YES
5712419	29234341	LT	7	Overall supervision	Overall supervision	-	Supervision	YES
5712419	29234341	MA	7	Paper writing	Paper writing	Wrote the paper	-	YES
5712419	29234341	RT	7	Paper writing	Paper writing	Wrote the paper	-	YES
5712419	29234341	SL	7	Paper writing	Paper writing	Wrote the paper	-	YES
5809627	29435671	ALD-P	2	helped us imagine the design of our study and improve it	helped us imagine the design of our study and improve it	Conceived and designed the experiments	Methodology	YES
5809627	29435671	DB	2	helped us with the technical aspect of the reconstruction algorithm	helped us with the technical aspect of the reconstruction algorithm	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5809627	29435671	MG	2	performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
5809627	29435671	PR	2	helped us imagine the design of our study and improve it	helped us imagine the design of our study and improve it	Conceived and designed the experiments	Methodology	YES
5809627	29435671	PYLR	2	helped us imagine the design of our study and improve it	helped us imagine the design of our study and improve it	Conceived and designed the experiments	Methodology	YES
5809627	29435671	PYS	2	helped us imagine the design of our study and improve it	helped us imagine the design of our study and improve it	Conceived and designed the experiments	Methodology	YES
5809627	29435671	Q. They	2	performed the interpretations of all bone scintigraphy and the redaction of the manuscript and its submission	performed the interpretations of all bone scintigraphy and the redaction of the manuscript and its submission	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5809627	29435671	RA	2	helped us imagine the design of our study and improve it	helped us imagine the design of our study and improve it	Conceived and designed the experiments	Methodology	YES
5809627	29435671	ZA	2	revised and wrote the intellectual content of the manuscript and helped at data and result interpretation	revised and wrote the intellectual content of the manuscript and helped at data and result interpretation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
1885215	17565369	AS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1885215	17565369	LS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1885215	17565369	LS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1885215	17565369	RG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1885215	17565369	RG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1885215	17565369	RG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1885215	17565369	RG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1885215	17565369	RG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1885215	17565369	SB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1885215	17565369	SB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5577768	28854876	H.R.	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5577768	28854876	HR	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5577768	28854876	JM	2	analysed all data	analysed all data	Analyzed the data	Formal analysis	YES
5577768	28854876	PP	2	performed all experiments	performed all experiments	Performed the experiments	Investigation	YES
5577768	28854876	SW	2	analysed all data	analysed all data	Analyzed the data	Formal analysis	YES
5577768	28854876	VI	2	performed all experiments|designed the study|analysed all data|drafted the manuscript	performed all experiments	Performed the experiments	Investigation	YES
5577768	28854876	VI	2	performed all experiments|designed the study|analysed all data|drafted the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5577768	28854876	VI	2	performed all experiments|designed the study|analysed all data|drafted the manuscript	analysed all data	Analyzed the data	Formal analysis	YES
5577768	28854876	VI	2	performed all experiments|designed the study|analysed all data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
3549746	23245800	All authors	2	have made substantive intellectual contributions towards conducting the study and preparing the manuscript for publication|read and approved the final manuscript	have made substantive intellectual contributions towards conducting the study and preparing the manuscript for publication	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3549746	23245800	All authors	2	have made substantive intellectual contributions towards conducting the study and preparing the manuscript for publication|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
3549746	23245800	CA	2	was involved in concept and design of the study, acquisition and interpretation of the data, drafting of the manuscript	was involved in concept and design of the study, acquisition and interpretation of the data, drafting of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
3549746	23245800	DTM	2	was responsible for concept and design of the study, analysis and interpretation of data, and revision of the manuscript	was responsible for concept and design of the study, analysis and interpretation of data, and revision of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Review & Editing	YES
3549746	23245800	LB	2	was responsible for securing funding for the study, concept and design of the study, overseeing ethical submission, data interpretation and drafting of the manuscript	was responsible for securing funding for the study, concept and design of the study, overseeing ethical submission, data interpretation and drafting of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Funding acquisition|Methodology|Supervision|Writing - Original Draft	YES
3549746	23245800	MR	2	was involved in concept and design of the study, gaining ethical clearance, subject recruitment, acquisition of the data, preparing tables and figures for publication, interpretation of the data and all aspects of writing the manuscript	was involved in concept and design of the study, gaining ethical clearance, subject recruitment, acquisition of the data, preparing tables and figures for publication, interpretation of the data and all aspects of writing the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Visualization|Writing - Original Draft	YES
3549746	23245800	NJ	2	was responsible for dietary standardisation and dispensing nutritional interventions, contributed to preparation of methodology, assisted with data analysis and review of manuscript	was responsible for dietary standardisation and dispensing nutritional interventions, contributed to preparation of methodology, assisted with data analysis and review of manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
3549746	23245800	PL	2	was responsible for concept and design of the study, interpretation of data, and revision of the manuscript	was responsible for concept and design of the study, interpretation of data, and revision of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Review & Editing	YES
4606149	26495291	Dacheng Qu	2	conceived of the analysis and helped write the paper	conceived of the analysis and helped write the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4606149	26495291	Hong Qu	2	conceived of the analysis and helped write the paper	conceived of the analysis and helped write the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4606149	26495291	Min Zhao	2	carried out analyses and helped write the paper|contributed equally	carried out analyses and helped write the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4606149	26495291	Min Zhao	2	carried out analyses and helped write the paper|contributed equally	contributed equally	-	-	NO
4606149	26495291	Yanming Chen	2	carried out analyses and helped write the paper|contributed equally	carried out analyses and helped write the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4606149	26495291	Yanming Chen	2	carried out analyses and helped write the paper|contributed equally	contributed equally	-	-	NO
3834604	24302874	Erez Nadir	4	The first draft of the paper was written by Vered Nir and by	The first draft of the paper was written by Vered Nir and by	Wrote the paper	Writing - Original Draft	YES
4414361	25923884	RH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414361	25923884	RH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414361	25923884	RH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414361	25923884	SB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414361	25923884	SB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414361	25923884	SB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414361	25923884	SB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5809632	29435678	AJ	2	conceived the study|developed statistical analysis plan and drafted the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5809632	29435678	AJ	2	conceived the study|developed statistical analysis plan and drafted the manuscript	developed statistical analysis plan and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5809632	29435678	DF	2	developed statistical analysis plan and drafted the manuscript|performed the statistical analysis	developed statistical analysis plan and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5809632	29435678	DF	2	developed statistical analysis plan and drafted the manuscript|performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
5809632	29435678	FZ	2	developed statistical analysis plan and drafted the manuscript|coordinated the effort	developed statistical analysis plan and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5809632	29435678	FZ	2	developed statistical analysis plan and drafted the manuscript|coordinated the effort	coordinated the effort	-	Project administration	YES
5809632	29435678	RB	2	conceived the study|developed statistical analysis plan and drafted the manuscript|performed the statistical analysis|coordinated the effort	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5809632	29435678	RB	2	conceived the study|developed statistical analysis plan and drafted the manuscript|performed the statistical analysis|coordinated the effort	developed statistical analysis plan and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5809632	29435678	RB	2	conceived the study|developed statistical analysis plan and drafted the manuscript|performed the statistical analysis|coordinated the effort	performed the statistical analysis	Analyzed the data	Formal analysis	YES
5809632	29435678	RB	2	conceived the study|developed statistical analysis plan and drafted the manuscript|performed the statistical analysis|coordinated the effort	coordinated the effort	-	Project administration	YES
5809632	29435678	TO	2	conceived the study|developed statistical analysis plan and drafted the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5809632	29435678	TO	2	conceived the study|developed statistical analysis plan and drafted the manuscript	developed statistical analysis plan and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5712420	29234337	AH	PLoS52	performed the molecular work	performed the molecular work	Performed the experiments	Investigation	YES
5712420	29234337	FW	PLoS52	designed the study|collected the data|performed the molecular work|analyzed the data|wrote the manuscript and all co-authors contributed substantially to revisions	designed the study	Conceived and designed the experiments	Methodology	YES
5712420	29234337	FW	PLoS52	designed the study|collected the data|performed the molecular work|analyzed the data|wrote the manuscript and all co-authors contributed substantially to revisions	collected the data	Performed the experiments	Investigation	YES
5712420	29234337	FW	PLoS52	designed the study|collected the data|performed the molecular work|analyzed the data|wrote the manuscript and all co-authors contributed substantially to revisions	performed the molecular work	Performed the experiments	Investigation	YES
5712420	29234337	FW	PLoS52	designed the study|collected the data|performed the molecular work|analyzed the data|wrote the manuscript and all co-authors contributed substantially to revisions	analyzed the data	Analyzed the data	Formal analysis	YES
5712420	29234337	FW	PLoS52	designed the study|collected the data|performed the molecular work|analyzed the data|wrote the manuscript and all co-authors contributed substantially to revisions	wrote the manuscript and all co-authors contributed substantially to revisions	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5712420	29234337	KS	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5712420	29234337	MvdH	PLoS52	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5712420	29234337	RW	PLoS52	collected the data|was responsible for the oscar field experiment	collected the data	Performed the experiments	Investigation	YES
5712420	29234337	RW	PLoS52	collected the data|was responsible for the oscar field experiment	was responsible for the oscar field experiment	Performed the experiments	Investigation	YES
1885216	17565370	EP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1885216	17565370	EP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1885216	17565370	EP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1885216	17565370	EP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1885216	17565370	JD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1885216	17565370	JD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1885216	17565370	JD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1885216	17565370	JD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1885216	17565370	JQ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1885216	17565370	JR	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1885216	17565370	JR	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1885216	17565370	PN	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1885216	17565370	PN	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1885216	17565370	TK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1885216	17565370	TK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1885216	17565370	TK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1885216	17565370	TN	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1885216	17565370	YP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5577849	28854898	CL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5577849	28854898	CW	PLoS5	Conceived and designed the experiments|Analyzed the data|Manuscript preparation	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5577849	28854898	CW	PLoS5	Conceived and designed the experiments|Analyzed the data|Manuscript preparation	Analyzed the data	Analyzed the data	Formal analysis	YES
5577849	28854898	CW	PLoS5	Conceived and designed the experiments|Analyzed the data|Manuscript preparation	Manuscript preparation	Wrote the paper	Writing - Original Draft	YES
5577849	28854898	FL	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
5577849	28854898	FL	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5577849	28854898	GX	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5577849	28854898	HZ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5577849	28854898	KC	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5577849	28854898	SZ	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5577849	28854898	YL	PLoS5	Performed the experiments|Analyzed the data|Manuscript preparation	Performed the experiments	Performed the experiments	Investigation	YES
5577849	28854898	YL	PLoS5	Performed the experiments|Analyzed the data|Manuscript preparation	Analyzed the data	Analyzed the data	Formal analysis	YES
5577849	28854898	YL	PLoS5	Performed the experiments|Analyzed the data|Manuscript preparation	Manuscript preparation	Wrote the paper	Writing - Original Draft	YES
5577849	28854898	YY	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5577849	28854898	ZL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
3549753	23316871	All authors	2	have given final approval of the version to be published	have given final approval of the version to be published	-	-	NO
3549753	23316871	PA	2	was involved in the conception, design, acquisition and analysis of the data and drafting the manuscript	was involved in the conception, design, acquisition and analysis of the data and drafting the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
5812956	29445878	AVL	2	prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5812956	29445878	DAH	2	prepared the manuscript and collected and analysed the data	prepared the manuscript and collected and analysed the data	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5812956	29445878	GAMSVD	2	prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5812956	29445878	KHK	2	collected the data and prepared the manuscript	collected the data and prepared the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5812956	29445878	OSH	2	analysed the data and prepared the manuscript	analysed the data and prepared the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5812956	29445878	RDB	2	prepared the manuscript and collected and analysed the data and is the principal investigator	prepared the manuscript and collected and analysed the data and is the principal investigator	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Funding acquisition|Investigation|Writing - Original Draft	YES
5712471	29234332	All authors	2	reviewed the results and approved the final version of the manuscript	reviewed the results and approved the final version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5712471	29234332	FY	2	conceived and coordinated the study|wrote the manuscript	conceived and coordinated the study	Conceived and designed the experiments	Conceptualization|Project administration	YES
5712471	29234332	FY	2	conceived and coordinated the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5712471	29234332	JS	2	provided technical assistance and contributed to the preparation of the figures	provided technical assistance and contributed to the preparation of the figures	Performed the experiments	Investigation|Visualization	YES
5712471	29234332	JZ	2	designed, performed, and analyzed the experiments shown in 3 figures , 4	designed, performed, and analyzed the experiments shown in 3 figures , 4	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology|Visualization	YES
5712471	29234332	LA	2	provided technical assistance and contributed to the preparation of the figures	provided technical assistance and contributed to the preparation of the figures	Performed the experiments	Investigation|Visualization	YES
5712471	29234332	RW	2	designed, performed, and analyzed the experiments shown in 6 figure	designed, performed, and analyzed the experiments shown in 6 figure	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology|Visualization	YES
5712471	29234332	SL	2	designed, performed, and analyzed the experiments shown in figures - 1 and supplemental data	designed, performed, and analyzed the experiments shown in figures - 1 and supplemental data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology|Visualization	YES
5712471	29234332	XL	2	provided technical assistance and contributed to the preparation of the figures	provided technical assistance and contributed to the preparation of the figures	Performed the experiments	Investigation|Visualization	YES
5712471	29234332	YL	2	designed, performed, and analyzed the experiments shown in 6 figure	designed, performed, and analyzed the experiments shown in 6 figure	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology|Visualization	YES
5712471	29234332	YQ	2	designed, performed, and analyzed the experiments shown in figures - 1 and supplemental data|designed, performed, and analyzed the experiments shown in 3 figures , 4|wrote the manuscript	designed, performed, and analyzed the experiments shown in figures - 1 and supplemental data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology|Visualization	YES
5712471	29234332	YQ	2	designed, performed, and analyzed the experiments shown in figures - 1 and supplemental data|designed, performed, and analyzed the experiments shown in 3 figures , 4|wrote the manuscript	designed, performed, and analyzed the experiments shown in 3 figures , 4	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology|Visualization	YES
5712471	29234332	YQ	2	designed, performed, and analyzed the experiments shown in figures - 1 and supplemental data|designed, performed, and analyzed the experiments shown in 3 figures , 4|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
1885217	17565372	RN	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1885217	17565372	RN	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1885217	17565372	RN	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1885217	17565372	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1885217	17565372	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1885217	17565372	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1885217	17565372	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5579935	28859623	TC	1	Conceived the study|Wrote the manuscript	Conceived the study	Conceived and designed the experiments	Conceptualization	YES
5579935	28859623	TC	1	Conceived the study|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5579935	28859623	VP	1	Conceived the study|Performed analyses|Wrote the manuscript	Conceived the study	Conceived and designed the experiments	Conceptualization	YES
5579935	28859623	VP	1	Conceived the study|Performed analyses|Wrote the manuscript	Performed analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5579935	28859623	VP	1	Conceived the study|Performed analyses|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4414362	25922942	DC	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414362	25922942	DC	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414362	25922942	EA	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414362	25922942	EA	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414362	25922942	KE	PLoS5	Input on design and assisted with revisions	Input on design and assisted with revisions	Conceived and designed the experiments|Wrote the paper	Writing - Review & Editing	YES
4414362	25922942	LB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414362	25922942	LB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414362	25922942	LB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414362	25922942	LM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414362	25922942	LM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414362	25922942	LM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414362	25922942	MW	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414362	25922942	MW	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414362	25922942	TG	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414362	25922942	TG	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414362	25922942	TG	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3562170	23347391	EKO	2	developed the study design, collected data, conducted statistical analysis, and drafted and submitted the manuscript	developed the study design, collected data, conducted statistical analysis, and drafted and submitted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
3562170	23347391	JEW	2	assisted in the study design, interpretation of data, and critically reviewed the manuscript	assisted in the study design, interpretation of data, and critically reviewed the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
3562170	23347391	MTR	2	assisted in the study design, interpretation of data, and critically reviewed the manuscript	assisted in the study design, interpretation of data, and critically reviewed the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
3562170	23347391	PAB	2	assisted in the study design, interpretation of data, and critically reviewed the manuscript	assisted in the study design, interpretation of data, and critically reviewed the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
3562170	23347391	SPP	2	assisted in the study design, interpretation of data, and critically reviewed the manuscript	assisted in the study design, interpretation of data, and critically reviewed the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
5712551	29238359	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4690820	26705241	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4690820	26705241	Christin Slomka	2	carried out the cultivation and expression experiments, the assays of enzyme activity, the establishment of hplc analysis and drafted the manuscript	carried out the cultivation and expression experiments, the assays of enzyme activity, the establishment of hplc analysis and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4690820	26705241	Christoph Syldatk	2	made contributions to the interpretation of data and participated in revising the article	made contributions to the interpretation of data and participated in revising the article	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
4690820	26705241	JR	2	made contributions to the interpretation of data and participated in revising the article	made contributions to the interpretation of data and participated in revising the article	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
4690820	26705241	SB	2	made contributions to the interpretation of data and participated in revising the article	made contributions to the interpretation of data and participated in revising the article	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
4690820	26705241	UE	2	made contributions to the interpretation of data and participated in revising the article	made contributions to the interpretation of data and participated in revising the article	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
1885218	17565373	AR	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1885218	17565373	AR	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1885218	17565373	MR	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1885218	17565373	MR	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1885218	17565373	MR	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1885218	17565373	RS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1885218	17565373	RS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1885218	17565373	RS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4606156	26495292	Hong Qu	2	carried out all analyses and helped write the paper|conceived the analysis and helped write the paper	carried out all analyses and helped write the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4606156	26495292	Hong Qu	2	carried out all analyses and helped write the paper|conceived the analysis and helped write the paper	conceived the analysis and helped write the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4606156	26495292	Min Zhao	2	conceived the analysis and helped write the paper	conceived the analysis and helped write the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4606156	26495292	Xueying Chen	2	carried out all analyses and helped write the paper	carried out all analyses and helped write the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5829280	29488080	AO	2	performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
5829280	29488080	BF	2	did the patient coordination	did the patient coordination	-	Project administration	YES
5829280	29488080	CHP	2	developed the study design and wrote the manuscript	developed the study design and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5829280	29488080	CS	2	developed the study design and wrote the manuscript	developed the study design and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5829280	29488080	FM	2	produced the amino acid infusion	produced the amino acid infusion	-	-	NO
5829280	29488080	ME	2	contributed on the manuscript	contributed on the manuscript	-	-	NO
5829280	29488080	PL	2	did the biochemical analysis	did the biochemical analysis	Performed the experiments	Investigation	YES
3565914	23286515	All authors	2	have made substantive intellectual contributions towards conducting the study and preparing the manuscript for publication	have made substantive intellectual contributions towards conducting the study and preparing the manuscript for publication	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3565914	23286515	CP	2	were involved in concept and design of the study, gaining ethical clearance, interpretation of the data and all aspects of writing the manuscript	were involved in concept and design of the study, gaining ethical clearance, interpretation of the data and all aspects of writing the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
3565914	23286515	IM	2	participated in subject recruitment, acquisition of the data, preparing tables and figures for publication, interpretation of the data and all aspects of writing the manuscript	participated in subject recruitment, acquisition of the data, preparing tables and figures for publication, interpretation of the data and all aspects of writing the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Visualization|Writing - Original Draft	YES
3565914	23286515	LV	2	were involved in concept and design of the study, gaining ethical clearance, interpretation of the data and all aspects of writing the manuscript	were involved in concept and design of the study, gaining ethical clearance, interpretation of the data and all aspects of writing the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
4414407	25923520	AB	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414407	25923520	AB	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414407	25923520	CDP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414407	25923520	CDP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414407	25923520	CDP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414407	25923520	CDP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414407	25923520	CDP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414407	25923520	DAKT	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4414407	25923520	DWC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414407	25923520	MCJW	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4414407	25923520	MP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414407	25923520	MP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414407	25923520	MP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414407	25923520	MP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414407	25923520	RJD	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414407	25923520	SO	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414407	25923520	SO	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414407	25923520	SO	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414407	25923520	TDMB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4414407	25923520	TDMB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5580217	28859611	ASH	2	performed all phenotypic evaluations, data analysis and manuscript preparation|conducted microarray experiments and analyzed the transcriptome data	performed all phenotypic evaluations, data analysis and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5580217	28859611	ASH	2	performed all phenotypic evaluations, data analysis and manuscript preparation|conducted microarray experiments and analyzed the transcriptome data	conducted microarray experiments and analyzed the transcriptome data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5580217	28859611	GD	2	conducted microarray experiments and analyzed the transcriptome data	conducted microarray experiments and analyzed the transcriptome data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5580217	28859611	ISK	2	performed all phenotypic evaluations, data analysis and manuscript preparation	performed all phenotypic evaluations, data analysis and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5580217	28859611	KVP	2	conducted microarray experiments and analyzed the transcriptome data	conducted microarray experiments and analyzed the transcriptome data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5580217	28859611	MK	2	conducted microarray experiments and analyzed the transcriptome data	conducted microarray experiments and analyzed the transcriptome data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5580217	28859611	MPJ	2	performed all phenotypic evaluations, data analysis and manuscript preparation	performed all phenotypic evaluations, data analysis and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5580217	28859611	PAK	2	involved in the designing of the experiments, data analysis, manuscript preparation and discussion	involved in the designing of the experiments, data analysis, manuscript preparation and discussion	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5580217	28859611	SA	2	performed all phenotypic evaluations, data analysis and manuscript preparation	performed all phenotypic evaluations, data analysis and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5580217	28859611	SG	2	performed all phenotypic evaluations, data analysis and manuscript preparation	performed all phenotypic evaluations, data analysis and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5580217	28859611	VSR	2	involved in the designing of the experiments, data analysis, manuscript preparation and discussion	involved in the designing of the experiments, data analysis, manuscript preparation and discussion	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5712565	29238355	AN	2	participated in data analysis	participated in data analysis	Analyzed the data	Formal analysis	YES
5712565	29238355	BK	2	performed the gene expression experiments, analyzed the data, and wrote the manuscript	performed the gene expression experiments, analyzed the data, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5712565	29238355	FM	2	participated in data analysis	participated in data analysis	Analyzed the data	Formal analysis	YES
5712565	29238355	GG	2	conceived the study and participated in writing of the manuscript	conceived the study and participated in writing of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5712565	29238355	PD	2	performed hormone measurements	performed hormone measurements	Performed the experiments	Investigation	YES
5712565	29238355	PV	2	performed protein analysis	performed protein analysis	Performed the experiments	Investigation	YES
5712565	29238355	RV	2	performed hormone measurements|conceived the study and participated in writing of the manuscript	performed hormone measurements	Performed the experiments	Investigation	YES
5712565	29238355	RV	2	performed hormone measurements|conceived the study and participated in writing of the manuscript	conceived the study and participated in writing of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4700032	26728467	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4700032	26728467	DB	2	helped in the wild type assays	helped in the wild type assays	Performed the experiments	Investigation	YES
4700032	26728467	OPC	2	performed the mutagenesis, purification and the assays	performed the mutagenesis, purification and the assays	Performed the experiments	Investigation	YES
4700032	26728467	SB	2	was responsible for the design of experiments, drafted the text and constructed wild type se3	was responsible for the design of experiments, drafted the text and constructed wild type se3	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
1885219	17565371	JS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1885219	17565371	JS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1885219	17565371	JS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1885219	17565371	MA	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1885219	17565371	MA	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1885219	17565371	SB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1885219	17565371	SB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1885219	17565371	SB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1885219	17565371	SB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1885219	17565371	SB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1885219	17565371	SS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1885219	17565371	SS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1885219	17565371	SS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1885219	17565371	VL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1885219	17565371	VL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1885219	17565371	VL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
3568064	23374455	JMW	2	prepared the draft of the position stand for review and editing by coauthors	prepared the draft of the position stand for review and editing by coauthors	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5829281	29488030	AdlF	2	performed the experiments, analyzed the data, and wrote the manuscript	performed the experiments, analyzed the data, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5829281	29488030	EE	2	performed the experiments, analyzed the data, and wrote the manuscript	performed the experiments, analyzed the data, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5829281	29488030	FR	2	designed the study and wrote the manuscript	designed the study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5829281	29488030	MA	2	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5829281	29488030	MM	2	designed the study and wrote the manuscript	designed the study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5829281	29488030	NM	2	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5829281	29488030	RZ	2	designed the study and wrote the manuscript	designed the study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5829281	29488030	SP	2	designed and performed the animal studies, analyzed the data, and wrote the manuscript	designed and performed the animal studies, analyzed the data, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4700033	26728466	Both authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4700033	26728466	KY	2	carried out the molecular genetic studies, participated in the sequence alignment and drafted the manuscript|contributed to the interpretations of the data	carried out the molecular genetic studies, participated in the sequence alignment and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4700033	26728466	KY	2	carried out the molecular genetic studies, participated in the sequence alignment and drafted the manuscript|contributed to the interpretations of the data	contributed to the interpretations of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
4700033	26728466	YT	2	contributed to the interpretations of the data	contributed to the interpretations of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5712577	29238357	MA	2	edited and added specific information to all sections	edited and added specific information to all sections	Wrote the paper	Writing - Review & Editing	YES
5712577	29238357	MM	2	edited and added specific information to all sections	edited and added specific information to all sections	Wrote the paper	Writing - Review & Editing	YES
5712577	29238357	VT	2	wrote review	wrote review	Wrote the paper	Writing - Original Draft	YES
5580268	28859626	BGL	2	conceived the study and designed the experiments	conceived the study and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5580268	28859626	FYY	2	carried out the experiments and analyzed the data	carried out the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5580268	28859626	JJG	2	carried out the experiments and analyzed the data	carried out the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5580268	28859626	LF	2	carried out the experiments and analyzed the data	carried out the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5580268	28859626	RM	2	guided and revised the article	guided and revised the article	Wrote the paper	Supervision|Writing - Review & Editing	YES
5580268	28859626	XJC	2	guided and revised the article	guided and revised the article	Wrote the paper	Supervision|Writing - Review & Editing	YES
5580268	28859626	YHS	2	conceived the study and designed the experiments|carried out the experiments and analyzed the data|wrote the manuscript	conceived the study and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5580268	28859626	YHS	2	conceived the study and designed the experiments|carried out the experiments and analyzed the data|wrote the manuscript	carried out the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5580268	28859626	YHS	2	conceived the study and designed the experiments|carried out the experiments and analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4414410	25923907	JC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414410	25923907	JC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414410	25923907	JC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414410	25923907	JC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414410	25923907	JC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414410	25923907	KG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414410	25923907	KG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414410	25923907	KG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414410	25923907	KG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414410	25923907	KG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414410	25923907	NL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414410	25923907	NL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414410	25923907	NL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3577439	23360586	AAA	2	each contributed equally to the formulation and writing of the manuscript	each contributed equally to the formulation and writing of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
3577439	23360586	BJS	2	each contributed equally to the formulation and writing of the manuscript	each contributed equally to the formulation and writing of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5833894	29492782	AP	2	are the principal investigators of this research and guarantors of integrity of the entire study design and manuscript writing	are the principal investigators of this research and guarantors of integrity of the entire study design and manuscript writing	Conceived and designed the experiments|Wrote the paper	Conceptualization|Funding acquisition|Methodology|Writing - Original Draft	YES
5833894	29492782	CT	2	scans and analyzed the images	scans and analyzed the images	Analyzed the data	Formal analysis|Visualization	YES
5833894	29492782	FP	2	analyzed the images and performed the dosimetric calculations	analyzed the images and performed the dosimetric calculations	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
5833894	29492782	GB	2	analyzed the images and performed the dosimetric calculations	analyzed the images and performed the dosimetric calculations	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
5833894	29492782	LC	2	contributed to the study design and manuscript editing and review	contributed to the study design and manuscript editing and review	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5833894	29492782	LG	2	contributed to the study design and manuscript editing and review	contributed to the study design and manuscript editing and review	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5833894	29492782	MC	2	contributed to the study design and manuscript editing and review	contributed to the study design and manuscript editing and review	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5833894	29492782	MG	2	contributed to the study design and manuscript editing and review	contributed to the study design and manuscript editing and review	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5833894	29492782	MP	2	performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
5833894	29492782	MU	2	are the principal investigators of this research and guarantors of integrity of the entire study design and manuscript writing|analyzed the images and performed the dosimetric calculations	are the principal investigators of this research and guarantors of integrity of the entire study design and manuscript writing	Conceived and designed the experiments|Wrote the paper	Conceptualization|Funding acquisition|Methodology|Writing - Original Draft	YES
5833894	29492782	MU	2	are the principal investigators of this research and guarantors of integrity of the entire study design and manuscript writing|analyzed the images and performed the dosimetric calculations	analyzed the images and performed the dosimetric calculations	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
5833894	29492782	SR	2	are the principal investigators of this research and guarantors of integrity of the entire study design and manuscript writing	are the principal investigators of this research and guarantors of integrity of the entire study design and manuscript writing	Conceived and designed the experiments|Wrote the paper	Conceptualization|Funding acquisition|Methodology|Writing - Original Draft	YES
1885284	17565379	DL	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1885284	17565379	DL	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1885284	17565379	GG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1885284	17565379	GG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1885284	17565379	GG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1885284	17565379	GG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1885284	17565379	HX	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1885284	17565379	JY	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1885284	17565379	KT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1885284	17565379	KT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1885284	17565379	KT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1885284	17565379	KT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1885284	17565379	LH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1885284	17565379	LK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1885284	17565379	MQ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1885284	17565379	MS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1885284	17565379	PJ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1885284	17565379	SW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1885284	17565379	TZ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1885284	17565379	TZ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1885284	17565379	TZ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1885284	17565379	XC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1885284	17565379	XD	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1885284	17565379	XT	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1885284	17565379	XY	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1885284	17565379	XY	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1885284	17565379	XY	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1885284	17565379	YD	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1885284	17565379	YF	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1885284	17565379	YF	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1885284	17565379	YF	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1885284	17565379	YK	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1885284	17565379	YZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1885284	17565379	ZC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5712589	29238358	AE	7	performed the research|analysed the data	performed the research	Performed the experiments	Investigation	YES
5712589	29238358	AE	7	performed the research|analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
5712589	29238358	DW	7	analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
5712589	29238358	EH	7	performed the research|analysed the data|wrote the paper	performed the research	Performed the experiments	Investigation	YES
5712589	29238358	EH	7	performed the research|analysed the data|wrote the paper	analysed the data	Analyzed the data	Formal analysis	YES
5712589	29238358	EH	7	performed the research|analysed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5712589	29238358	GD	7	analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
5712589	29238358	JK	7	analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
5712589	29238358	MH	7	designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
5712589	29238358	MW	7	performed the research|analysed the data	performed the research	Performed the experiments	Investigation	YES
5712589	29238358	MW	7	performed the research|analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
5712589	29238358	PB	7	performed the research|analysed the data	performed the research	Performed the experiments	Investigation	YES
5712589	29238358	PB	7	performed the research|analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
5712589	29238358	RH	7	designed the research|wrote the paper	designed the research	Conceived and designed the experiments	Methodology	YES
5712589	29238358	RH	7	designed the research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4710622	26759120	JF	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4710622	26759120	MAN	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4710622	26759120	MAN	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4710622	26759120	MAN	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4710622	26759120	MH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4710622	26759120	MH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4710622	26759120	RSA	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4710622	26759120	RSA	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4710622	26759120	all authors	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
3577441	23402535	AN	2	contributed to the interpretation	contributed to the interpretation	Analyzed the data	Formal analysis	YES
3577441	23402535	HI	2	was the primary author of the manuscript	was the primary author of the manuscript	Wrote the paper	Writing - Original Draft	YES
3577441	23402535	KI	2	designed the study and contributed to the interpretation	designed the study and contributed to the interpretation	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
3577441	23402535	KK	2	designed the study and contributed to the interpretation	designed the study and contributed to the interpretation	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
3577441	23402535	KM	2	assessed dietary intake of the subjects and contributed to the data analysis and interpretation	assessed dietary intake of the subjects and contributed to the data analysis and interpretation	Analyzed the data	Formal analysis	YES
3577441	23402535	KO	2	assessed dietary intake of the subjects and contributed to the data analysis and interpretation	assessed dietary intake of the subjects and contributed to the data analysis and interpretation	Analyzed the data	Formal analysis	YES
3577441	23402535	NM	2	assessed dietary intake of the subjects and contributed to the data analysis and interpretation	assessed dietary intake of the subjects and contributed to the data analysis and interpretation	Analyzed the data	Formal analysis	YES
3577441	23402535	RO	2	assessed dietary intake of the subjects and contributed to the data analysis and interpretation	assessed dietary intake of the subjects and contributed to the data analysis and interpretation	Analyzed the data	Formal analysis	YES
3577441	23402535	YY	2	designed the study and contributed to the interpretation	designed the study and contributed to the interpretation	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
4544680	26047625	C Sert	5	were involved in: analysis and interpretation of the data	were involved in: analysis and interpretation of the data	Analyzed the data	Formal analysis	YES
4544680	26047625	K Lee	5	were involved in: patient enrolment into the study	were involved in: patient enrolment into the study	-	-	NO
4544680	26047625	L Rozhinskaya	5	were involved in: patient enrolment into the study	were involved in: patient enrolment into the study	-	-	NO
4544680	26047625	M D Bronstein	5	were involved in: patient enrolment into the study	were involved in: patient enrolment into the study	-	-	NO
4544680	26047625	M Gadelha	5	were involved in: patient enrolment into the study	were involved in: patient enrolment into the study	-	-	NO
4544680	26047625	P Maisonobe	5	were involved in: analysis and interpretation of the data	were involved in: analysis and interpretation of the data	Analyzed the data	Formal analysis	YES
5580281	28859614	CY	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5580281	28859614	DR	PLoS52	designed the experiments|drafted the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5580281	28859614	DR	PLoS52	designed the experiments|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5580281	28859614	LH	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5580281	28859614	LQ	PLoS52	designed the experiments|performed the experiments|drafted the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5580281	28859614	LQ	PLoS52	designed the experiments|performed the experiments|drafted the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5580281	28859614	LQ	PLoS52	designed the experiments|performed the experiments|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5580281	28859614	LX	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5580281	28859614	PCR	PLoS52	proteomic data	proteomic data	-	-	NO
5580281	28859614	RT	PLoS52	proteomic data	proteomic data	-	-	NO
5580281	28859614	XH	PLoS52	designed the experiments|performed the experiments|drafted the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5580281	28859614	XH	PLoS52	designed the experiments|performed the experiments|drafted the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5580281	28859614	XH	PLoS52	designed the experiments|performed the experiments|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5580281	28859614	XL	PLoS52	designed the experiments|performed the experiments|drafted the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5580281	28859614	XL	PLoS52	designed the experiments|performed the experiments|drafted the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5580281	28859614	XL	PLoS52	designed the experiments|performed the experiments|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5580281	28859614	YL	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5580281	28859614	all authors	PLoS52	read, helped revise, and approved the final manuscript	read, helped revise, and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
3577454	23402493	AH	2	developed the study design|participated in data collection	developed the study design	Conceived and designed the experiments	Methodology	YES
3577454	23402493	AH	2	developed the study design|participated in data collection	participated in data collection	Performed the experiments	Investigation	YES
3577454	23402493	AM	2	developed the study design|participated in data collection	developed the study design	Conceived and designed the experiments	Methodology	YES
3577454	23402493	AM	2	developed the study design|participated in data collection	participated in data collection	Performed the experiments	Investigation	YES
3577454	23402493	All authors	2	contributed to drafting of the manuscript	contributed to drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
3577454	23402493	CGS	2	developed the study design|participated in data collection	developed the study design	Conceived and designed the experiments	Methodology	YES
3577454	23402493	CGS	2	developed the study design|participated in data collection	participated in data collection	Performed the experiments	Investigation	YES
3577454	23402493	EG	2	developed the study design|was responsible for carrying out mrna expression analysis	developed the study design	Conceived and designed the experiments	Methodology	YES
3577454	23402493	EG	2	developed the study design|was responsible for carrying out mrna expression analysis	was responsible for carrying out mrna expression analysis	Performed the experiments	Investigation	YES
3577454	23402493	KH	2	developed the study design|was in charge of subject recruitment, data collection and management, statistical analysis	developed the study design	Conceived and designed the experiments	Methodology	YES
3577454	23402493	KH	2	developed the study design|was in charge of subject recruitment, data collection and management, statistical analysis	was in charge of subject recruitment, data collection and management, statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5834417	29500717	AF	2	carried out the experiments and analysed the data|interpreted the data and analysed results|drafted the manuscript and all authors revised and approved the final manuscript to be published	carried out the experiments and analysed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5834417	29500717	AF	2	carried out the experiments and analysed the data|interpreted the data and analysed results|drafted the manuscript and all authors revised and approved the final manuscript to be published	interpreted the data and analysed results	Analyzed the data	Formal analysis	YES
5834417	29500717	AF	2	carried out the experiments and analysed the data|interpreted the data and analysed results|drafted the manuscript and all authors revised and approved the final manuscript to be published	drafted the manuscript and all authors revised and approved the final manuscript to be published	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5834417	29500717	AW	2	carried out the experiments and analysed the data|interpreted the data and analysed results	carried out the experiments and analysed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5834417	29500717	AW	2	carried out the experiments and analysed the data|interpreted the data and analysed results	interpreted the data and analysed results	Analyzed the data	Formal analysis	YES
5834417	29500717	GS	2	carried out the experiments and analysed the data|interpreted the data and analysed results	carried out the experiments and analysed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5834417	29500717	GS	2	carried out the experiments and analysed the data|interpreted the data and analysed results	interpreted the data and analysed results	Analyzed the data	Formal analysis	YES
5834417	29500717	GZ	2	contributed in the study design and data acquisition	contributed in the study design and data acquisition	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources	YES
5834417	29500717	IK	2	interpreted the data and analysed results	interpreted the data and analysed results	Analyzed the data	Formal analysis	YES
5834417	29500717	RG	2	interpreted the data and analysed results|contributed in the study design and data acquisition	interpreted the data and analysed results	Analyzed the data	Formal analysis	YES
5834417	29500717	RG	2	interpreted the data and analysed results|contributed in the study design and data acquisition	contributed in the study design and data acquisition	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources	YES
5834417	29500717	SL	2	contributed in the study design and data acquisition	contributed in the study design and data acquisition	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources	YES
4414411	25923814	AP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Revised the article critically for important intellectual content|Gave final approval of the version to be published	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414411	25923814	AP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Revised the article critically for important intellectual content|Gave final approval of the version to be published	Performed the experiments	Performed the experiments	Investigation	YES
4414411	25923814	AP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Revised the article critically for important intellectual content|Gave final approval of the version to be published	Analyzed the data	Analyzed the data	Formal analysis	YES
4414411	25923814	AP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Revised the article critically for important intellectual content|Gave final approval of the version to be published	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414411	25923814	AP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Revised the article critically for important intellectual content|Gave final approval of the version to be published	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414411	25923814	AP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Revised the article critically for important intellectual content|Gave final approval of the version to be published	Revised the article critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4414411	25923814	AP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Revised the article critically for important intellectual content|Gave final approval of the version to be published	Gave final approval of the version to be published	-	-	NO
4414411	25923814	GE	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Revised the article critically for important intellectual content|Gave final approval of the version to be published	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414411	25923814	GE	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Revised the article critically for important intellectual content|Gave final approval of the version to be published	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414411	25923814	GE	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Revised the article critically for important intellectual content|Gave final approval of the version to be published	Revised the article critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4414411	25923814	GE	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Revised the article critically for important intellectual content|Gave final approval of the version to be published	Gave final approval of the version to be published	-	-	NO
3583121	22564864	MJB	2	oversaw data collection and statistical analyses, and also led the writing of the manuscript	oversaw data collection and statistical analyses, and also led the writing of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Supervision|Writing - Original Draft	YES
3583121	22564864	RDH	2	secured funding that assisted with this research and assisted in the development of the study, and in the development and writing of the draft manuscript	secured funding that assisted with this research and assisted in the development of the study, and in the development and writing of the draft manuscript	Wrote the paper	Funding acquisition|Writing - Original Draft	YES
3583121	22564864	SMH	2	measured and analyzed some of the biochemical parameters and assisted in the development and writing of the draft manuscript	measured and analyzed some of the biochemical parameters and assisted in the development and writing of the draft manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3583121	22564864	SRS	2	conceived the idea for the study, obtained funding, led the development of the study design, obtained ethical approval, and assisted in manuscript preparation	conceived the idea for the study, obtained funding, led the development of the study design, obtained ethical approval, and assisted in manuscript preparation	Conceived and designed the experiments|Wrote the paper	Conceptualization|Funding acquisition|Methodology|Project administration|Writing - Original Draft	YES
3583121	22564864	TM	2	contributed to the development of the study design, raw data collection, and obtainment of ethical approval	contributed to the development of the study design, raw data collection, and obtainment of ethical approval	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Project administration|Resources	YES
3583121	22564864	YM	2	conceived the idea for the study, contributed to the development of the study design, and primarily responsible for raw data collection	conceived the idea for the study, contributed to the development of the study design, and primarily responsible for raw data collection	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceptualization|Investigation|Methodology|Resources	YES
1885285	17565380	AG	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1885285	17565380	GB	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1885285	17565380	GB	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1885285	17565380	JR	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1885285	17565380	LC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1885285	17565380	MF	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1885285	17565380	MH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1885285	17565380	MJ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1885285	17565380	MS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1885285	17565380	OS	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1885285	17565380	PA	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1885285	17565380	PC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1885285	17565380	PC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1885285	17565380	PC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1885285	17565380	PD	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1885285	17565380	PD	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1885285	17565380	SO	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1885285	17565380	SO	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1885285	17565380	SO	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4713403	26769491	AK	2	contributed to the interpretations of the data|were responsible for the design of experiments	contributed to the interpretations of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
4713403	26769491	AK	2	contributed to the interpretations of the data|were responsible for the design of experiments	were responsible for the design of experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4713403	26769491	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4713403	26769491	TB	2	carried out the molecular genetic studies, and drafted the manuscript|contributed to the interpretations of the data	carried out the molecular genetic studies, and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4713403	26769491	TB	2	carried out the molecular genetic studies, and drafted the manuscript|contributed to the interpretations of the data	contributed to the interpretations of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
4713403	26769491	TH	2	contributed to the interpretations of the data|were responsible for the design of experiments	contributed to the interpretations of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
4713403	26769491	TH	2	contributed to the interpretations of the data|were responsible for the design of experiments	were responsible for the design of experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4713403	26769491	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5712803	29238352	AC	2	designed the experiment, performed the data analysis and wrote the manuscript	designed the experiment, performed the data analysis and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5712803	29238352	CC	2	evaluated the tolerance of the transgenic plants to drought and salinity stresses	evaluated the tolerance of the transgenic plants to drought and salinity stresses	Performed the experiments	Investigation	YES
5712803	29238352	JL	2	analyzed the expression level of the abiotic stress related gene in the transgenic plants	analyzed the expression level of the abiotic stress related gene in the transgenic plants	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5712803	29238352	JX	2	conducted the bioinformatics analysis	conducted the bioinformatics analysis	Performed the experiments	Formal analysis|Investigation	YES
5712803	29238352	LX	2	designed the experiment, performed the data analysis and wrote the manuscript	designed the experiment, performed the data analysis and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5712803	29238352	RZ	2	collected the data of the agronomic traits and evaluated the powdery mildew resistance in the field using high generations of the transgenic plants	collected the data of the agronomic traits and evaluated the powdery mildew resistance in the field using high generations of the transgenic plants	Performed the experiments	Investigation	YES
5712803	29238352	WY	2	collected the data of the agronomic traits and evaluated the powdery mildew resistance in the field using high generations of the transgenic plants	collected the data of the agronomic traits and evaluated the powdery mildew resistance in the field using high generations of the transgenic plants	Performed the experiments	Investigation	YES
5712803	29238352	XWdesigned	2	the experiment to screen the pathogen induced genes in haynaldia villosa	the experiment to screen the pathogen induced genes in haynaldia villosa	Performed the experiments	Investigation	YES
5712803	29238352	XyW	2	cloned the erf1-v gene and detected the responses of erf1-v to biotic and abiotic stresses	cloned the erf1-v gene and detected the responses of erf1-v to biotic and abiotic stresses	Performed the experiments	Investigation	YES
5712803	29238352	ZD	2	evaluated the tolerance of the transgenic plants to drought and salinity stresses	evaluated the tolerance of the transgenic plants to drought and salinity stresses	Performed the experiments	Investigation	YES
5838028	29508107	GKA-A	2	made substantial contributions to the conception and design|contributed to the acquisition of the data or analysis and interpretation of the data|drafted the article or revised it critically for important intellectual content|did the final approval of the version to be published	made substantial contributions to the conception and design	Conceived and designed the experiments	Conceptualization	YES
5838028	29508107	GKA-A	2	made substantial contributions to the conception and design|contributed to the acquisition of the data or analysis and interpretation of the data|drafted the article or revised it critically for important intellectual content|did the final approval of the version to be published	contributed to the acquisition of the data or analysis and interpretation of the data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5838028	29508107	GKA-A	2	made substantial contributions to the conception and design|contributed to the acquisition of the data or analysis and interpretation of the data|drafted the article or revised it critically for important intellectual content|did the final approval of the version to be published	drafted the article or revised it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5838028	29508107	GKA-A	2	made substantial contributions to the conception and design|contributed to the acquisition of the data or analysis and interpretation of the data|drafted the article or revised it critically for important intellectual content|did the final approval of the version to be published	did the final approval of the version to be published	-	-	NO
5838028	29508107	JAC	2	made substantial contributions to the conception and design|contributed to the acquisition of the data or analysis and interpretation of the data|drafted the article or revised it critically for important intellectual content|did the final approval of the version to be published	made substantial contributions to the conception and design	Conceived and designed the experiments	Conceptualization	YES
5838028	29508107	JAC	2	made substantial contributions to the conception and design|contributed to the acquisition of the data or analysis and interpretation of the data|drafted the article or revised it critically for important intellectual content|did the final approval of the version to be published	contributed to the acquisition of the data or analysis and interpretation of the data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5838028	29508107	JAC	2	made substantial contributions to the conception and design|contributed to the acquisition of the data or analysis and interpretation of the data|drafted the article or revised it critically for important intellectual content|did the final approval of the version to be published	drafted the article or revised it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5838028	29508107	JAC	2	made substantial contributions to the conception and design|contributed to the acquisition of the data or analysis and interpretation of the data|drafted the article or revised it critically for important intellectual content|did the final approval of the version to be published	did the final approval of the version to be published	-	-	NO
5838028	29508107	JAOD	2	made substantial contributions to the conception and design|contributed to the acquisition of the data or analysis and interpretation of the data|drafted the article or revised it critically for important intellectual content|did the final approval of the version to be published	made substantial contributions to the conception and design	Conceived and designed the experiments	Conceptualization	YES
5838028	29508107	JAOD	2	made substantial contributions to the conception and design|contributed to the acquisition of the data or analysis and interpretation of the data|drafted the article or revised it critically for important intellectual content|did the final approval of the version to be published	contributed to the acquisition of the data or analysis and interpretation of the data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5838028	29508107	JAOD	2	made substantial contributions to the conception and design|contributed to the acquisition of the data or analysis and interpretation of the data|drafted the article or revised it critically for important intellectual content|did the final approval of the version to be published	drafted the article or revised it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5838028	29508107	JAOD	2	made substantial contributions to the conception and design|contributed to the acquisition of the data or analysis and interpretation of the data|drafted the article or revised it critically for important intellectual content|did the final approval of the version to be published	did the final approval of the version to be published	-	-	NO
5838028	29508107	NO	2	made substantial contributions to the conception and design|contributed to the acquisition of the data or analysis and interpretation of the data|drafted the article or revised it critically for important intellectual content|did the final approval of the version to be published	made substantial contributions to the conception and design	Conceived and designed the experiments	Conceptualization	YES
5838028	29508107	NO	2	made substantial contributions to the conception and design|contributed to the acquisition of the data or analysis and interpretation of the data|drafted the article or revised it critically for important intellectual content|did the final approval of the version to be published	contributed to the acquisition of the data or analysis and interpretation of the data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5838028	29508107	NO	2	made substantial contributions to the conception and design|contributed to the acquisition of the data or analysis and interpretation of the data|drafted the article or revised it critically for important intellectual content|did the final approval of the version to be published	drafted the article or revised it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5838028	29508107	NO	2	made substantial contributions to the conception and design|contributed to the acquisition of the data or analysis and interpretation of the data|drafted the article or revised it critically for important intellectual content|did the final approval of the version to be published	did the final approval of the version to be published	-	-	NO
5838028	29508107	NP-T	2	made substantial contributions to the conception and design|contributed to the acquisition of the data or analysis and interpretation of the data|drafted the article or revised it critically for important intellectual content|did the final approval of the version to be published	made substantial contributions to the conception and design	Conceived and designed the experiments	Conceptualization	YES
5838028	29508107	NP-T	2	made substantial contributions to the conception and design|contributed to the acquisition of the data or analysis and interpretation of the data|drafted the article or revised it critically for important intellectual content|did the final approval of the version to be published	contributed to the acquisition of the data or analysis and interpretation of the data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5838028	29508107	NP-T	2	made substantial contributions to the conception and design|contributed to the acquisition of the data or analysis and interpretation of the data|drafted the article or revised it critically for important intellectual content|did the final approval of the version to be published	drafted the article or revised it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5838028	29508107	NP-T	2	made substantial contributions to the conception and design|contributed to the acquisition of the data or analysis and interpretation of the data|drafted the article or revised it critically for important intellectual content|did the final approval of the version to be published	did the final approval of the version to be published	-	-	NO
5838028	29508107	PMS-J	2	made substantial contributions to the conception and design|contributed to the acquisition of the data or analysis and interpretation of the data|drafted the article or revised it critically for important intellectual content|did the final approval of the version to be published	made substantial contributions to the conception and design	Conceived and designed the experiments	Conceptualization	YES
5838028	29508107	PMS-J	2	made substantial contributions to the conception and design|contributed to the acquisition of the data or analysis and interpretation of the data|drafted the article or revised it critically for important intellectual content|did the final approval of the version to be published	contributed to the acquisition of the data or analysis and interpretation of the data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5838028	29508107	PMS-J	2	made substantial contributions to the conception and design|contributed to the acquisition of the data or analysis and interpretation of the data|drafted the article or revised it critically for important intellectual content|did the final approval of the version to be published	drafted the article or revised it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5838028	29508107	PMS-J	2	made substantial contributions to the conception and design|contributed to the acquisition of the data or analysis and interpretation of the data|drafted the article or revised it critically for important intellectual content|did the final approval of the version to be published	did the final approval of the version to be published	-	-	NO
5838028	29508107	SKL	2	contributed to the acquisition of the data or analysis and interpretation of the data|drafted the article or revised it critically for important intellectual content|did the final approval of the version to be published	contributed to the acquisition of the data or analysis and interpretation of the data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5838028	29508107	SKL	2	contributed to the acquisition of the data or analysis and interpretation of the data|drafted the article or revised it critically for important intellectual content|did the final approval of the version to be published	drafted the article or revised it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5838028	29508107	SKL	2	contributed to the acquisition of the data or analysis and interpretation of the data|drafted the article or revised it critically for important intellectual content|did the final approval of the version to be published	did the final approval of the version to be published	-	-	NO
5838028	29508107	SML	2	made substantial contributions to the conception and design|contributed to the acquisition of the data or analysis and interpretation of the data|drafted the article or revised it critically for important intellectual content|did the final approval of the version to be published	made substantial contributions to the conception and design	Conceived and designed the experiments	Conceptualization	YES
5838028	29508107	SML	2	made substantial contributions to the conception and design|contributed to the acquisition of the data or analysis and interpretation of the data|drafted the article or revised it critically for important intellectual content|did the final approval of the version to be published	contributed to the acquisition of the data or analysis and interpretation of the data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5838028	29508107	SML	2	made substantial contributions to the conception and design|contributed to the acquisition of the data or analysis and interpretation of the data|drafted the article or revised it critically for important intellectual content|did the final approval of the version to be published	drafted the article or revised it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5838028	29508107	SML	2	made substantial contributions to the conception and design|contributed to the acquisition of the data or analysis and interpretation of the data|drafted the article or revised it critically for important intellectual content|did the final approval of the version to be published	did the final approval of the version to be published	-	-	NO
5838028	29508107	SR	2	contributed to the acquisition of the data or analysis and interpretation of the data|drafted the article or revised it critically for important intellectual content|did the final approval of the version to be published	contributed to the acquisition of the data or analysis and interpretation of the data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5838028	29508107	SR	2	contributed to the acquisition of the data or analysis and interpretation of the data|drafted the article or revised it critically for important intellectual content|did the final approval of the version to be published	drafted the article or revised it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5838028	29508107	SR	2	contributed to the acquisition of the data or analysis and interpretation of the data|drafted the article or revised it critically for important intellectual content|did the final approval of the version to be published	did the final approval of the version to be published	-	-	NO
5838028	29508107	TO	2	made substantial contributions to the conception and design|contributed to the acquisition of the data or analysis and interpretation of the data|drafted the article or revised it critically for important intellectual content|did the final approval of the version to be published	made substantial contributions to the conception and design	Conceived and designed the experiments	Conceptualization	YES
5838028	29508107	TO	2	made substantial contributions to the conception and design|contributed to the acquisition of the data or analysis and interpretation of the data|drafted the article or revised it critically for important intellectual content|did the final approval of the version to be published	contributed to the acquisition of the data or analysis and interpretation of the data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5838028	29508107	TO	2	made substantial contributions to the conception and design|contributed to the acquisition of the data or analysis and interpretation of the data|drafted the article or revised it critically for important intellectual content|did the final approval of the version to be published	drafted the article or revised it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5838028	29508107	TO	2	made substantial contributions to the conception and design|contributed to the acquisition of the data or analysis and interpretation of the data|drafted the article or revised it critically for important intellectual content|did the final approval of the version to be published	did the final approval of the version to be published	-	-	NO
5838028	29508107	VB	2	contributed to the acquisition of the data or analysis and interpretation of the data|drafted the article or revised it critically for important intellectual content|did the final approval of the version to be published	contributed to the acquisition of the data or analysis and interpretation of the data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5838028	29508107	VB	2	contributed to the acquisition of the data or analysis and interpretation of the data|drafted the article or revised it critically for important intellectual content|did the final approval of the version to be published	drafted the article or revised it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5838028	29508107	VB	2	contributed to the acquisition of the data or analysis and interpretation of the data|drafted the article or revised it critically for important intellectual content|did the final approval of the version to be published	did the final approval of the version to be published	-	-	NO
5580312	28859620	AH	2	helped interpret the biological significance of results|wrote the manuscript	helped interpret the biological significance of results	Analyzed the data	Formal analysis	YES
5580312	28859620	AH	2	helped interpret the biological significance of results|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5580312	28859620	JO	2	helped interpret the biological significance of results|wrote the manuscript	helped interpret the biological significance of results	Analyzed the data	Formal analysis	YES
5580312	28859620	JO	2	helped interpret the biological significance of results|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5580312	28859620	RVR	2	conceptualised the study|designed the pipeline and wrote the scripts|wrote the manuscript	conceptualised the study	Conceived and designed the experiments	Conceptualization	YES
5580312	28859620	RVR	2	conceptualised the study|designed the pipeline and wrote the scripts|wrote the manuscript	designed the pipeline and wrote the scripts	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Software|Writing - Original Draft	YES
5580312	28859620	RVR	2	conceptualised the study|designed the pipeline and wrote the scripts|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5580312	28859620	SFL	2	conceptualised the study|helped interpret the biological significance of results|wrote the manuscript	conceptualised the study	Conceived and designed the experiments	Conceptualization	YES
5580312	28859620	SFL	2	conceptualised the study|helped interpret the biological significance of results|wrote the manuscript	helped interpret the biological significance of results	Analyzed the data	Formal analysis	YES
5580312	28859620	SFL	2	conceptualised the study|helped interpret the biological significance of results|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4414412	25923975	ARH	PLoS5	Analyzed the data|Critical reading from	Analyzed the data	Analyzed the data	Formal analysis	YES
4414412	25923975	ARH	PLoS5	Analyzed the data|Critical reading from	Critical reading from	-	-	NO
4414412	25923975	JCS	PLoS5	Performed the experiments|Critical reading from	Performed the experiments	Performed the experiments	Investigation	YES
4414412	25923975	JCS	PLoS5	Performed the experiments|Critical reading from	Critical reading from	-	-	NO
4414412	25923975	JNS	PLoS5	Performed the experiments|Critical reading from	Performed the experiments	Performed the experiments	Investigation	YES
4414412	25923975	JNS	PLoS5	Performed the experiments|Critical reading from	Critical reading from	-	-	NO
4414412	25923975	JPS	PLoS5	Performed the experiments|Critical reading from	Performed the experiments	Performed the experiments	Investigation	YES
4414412	25923975	JPS	PLoS5	Performed the experiments|Critical reading from	Critical reading from	-	-	NO
4414412	25923975	MCVP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414412	25923975	MCVP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414412	25923975	MCVP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414412	25923975	MCVP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414412	25923975	MLA	PLoS5	Performed the experiments|Analyzed the data|Critical reading from	Performed the experiments	Performed the experiments	Investigation	YES
4414412	25923975	MLA	PLoS5	Performed the experiments|Analyzed the data|Critical reading from	Analyzed the data	Analyzed the data	Formal analysis	YES
4414412	25923975	MLA	PLoS5	Performed the experiments|Analyzed the data|Critical reading from	Critical reading from	-	-	NO
4414412	25923975	PMM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414412	25923975	PMM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414412	25923975	PMM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414412	25923975	PMM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414412	25923975	SEP	PLoS5	Conceived and designed the experiments|Critical reading from	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414412	25923975	SEP	PLoS5	Conceived and designed the experiments|Critical reading from	Critical reading from	-	-	NO
4414412	25923975	ZS	PLoS5	Analyzed the data|Critical reading from	Analyzed the data	Analyzed the data	Formal analysis	YES
4414412	25923975	ZS	PLoS5	Analyzed the data|Critical reading from	Critical reading from	-	-	NO
3583772	23402436	CHK	PLoS52	designed the experiments|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
3583772	23402436	CHK	PLoS52	designed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3583772	23402436	CWH	PLoS52	designed the experiments|performed the experiments|performed the statistical analyses|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
3583772	23402436	CWH	PLoS52	designed the experiments|performed the experiments|performed the statistical analyses|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
3583772	23402436	CWH	PLoS52	designed the experiments|performed the experiments|performed the statistical analyses|wrote the manuscript	performed the statistical analyses	Analyzed the data	Formal analysis	YES
3583772	23402436	CWH	PLoS52	designed the experiments|performed the experiments|performed the statistical analyses|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3583772	23402436	CYC	PLoS52	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
3583772	23402436	CYH	PLoS52	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
3583772	23402436	JLI	PLoS52	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3583772	23402436	WHC	PLoS52	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
3583772	23402436	YST	PLoS52	designed the experiments|performed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
3583772	23402436	YST	PLoS52	designed the experiments|performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
1885551	17565366	AH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1885551	17565366	AH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1885551	17565366	AH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1885551	17565366	EV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1885551	17565366	EV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1885551	17565366	EV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1885551	17565366	EV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1885551	17565366	LT	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1885551	17565366	LT	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5712850	29238354	All authors	2	commented on the manuscript	commented on the manuscript	-	-	NO
5712850	29238354	BH	2	was involved in experiment planning	was involved in experiment planning	Conceived and designed the experiments	Methodology	YES
5712850	29238354	DV	2	planned, carried out and analyzed co-ip experiments, carried out go-term and network analysis and analyzed protein properties	planned, carried out and analyzed co-ip experiments, carried out go-term and network analysis and analyzed protein properties	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation	YES
5712850	29238354	JS	2	carried out and analyzed co-ip experiments	carried out and analyzed co-ip experiments	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5712850	29238354	KB	2	carried out go-term analysis and analyzed published transcript abundances	carried out go-term analysis and analyzed published transcript abundances	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5712850	29238354	MBa	2	cloned plasmids and carried out transient expression in nicotiana benthamiana	cloned plasmids and carried out transient expression in nicotiana benthamiana	Performed the experiments	Investigation	YES
5712850	29238354	MBu	2	generated and analyzed glucosinolate data and contributed to statistics, experimental and project design	generated and analyzed glucosinolate data and contributed to statistics, experimental and project design	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5712850	29238354	SN	2	generated cdna libraries and yeast 2-hybrid baits, planned and carried out yeast 2-hybrid experiments, generated arabidopsis lines stably expressing fluorophore-tagged enzymes, generated lines carrying multiple t-dna insertions, analyzed glucosinolate data, carried out statistical analysis and confocal microscopy and drafted the manuscript	generated cdna libraries and yeast 2-hybrid baits, planned and carried out yeast 2-hybrid experiments, generated arabidopsis lines stably expressing fluorophore-tagged enzymes, generated lines carrying multiple t-dna insertions, analyzed glucosinolate data, carried out statistical analysis and confocal microscopy and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
5580439	28863779	All the authors	2	contributed to the writing of the manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5580439	28863779	CRL	2	participated in the planning and coordination of the study and in the manuscript correction	participated in the planning and coordination of the study and in the manuscript correction	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Review & Editing	YES
5580439	28863779	DSD	2	provided the termite species for the experiments|participated in the planning and coordination of the study and in the manuscript correction	provided the termite species for the experiments	-	-	NO
5580439	28863779	DSD	2	provided the termite species for the experiments|participated in the planning and coordination of the study and in the manuscript correction	participated in the planning and coordination of the study and in the manuscript correction	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Review & Editing	YES
5580439	28863779	MC	2	analysed the results|wrote the manuscript|participated in the planning and coordination of the study and in the manuscript correction	analysed the results	Analyzed the data	Formal analysis	YES
5580439	28863779	MC	2	analysed the results|wrote the manuscript|participated in the planning and coordination of the study and in the manuscript correction	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5580439	28863779	MC	2	analysed the results|wrote the manuscript|participated in the planning and coordination of the study and in the manuscript correction	participated in the planning and coordination of the study and in the manuscript correction	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Review & Editing	YES
5580439	28863779	MM	2	analysed the results|wrote the manuscript	analysed the results	Analyzed the data	Formal analysis	YES
5580439	28863779	MM	2	analysed the results|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5580439	28863779	PD	2	participated in the planning and coordination of the study and in the manuscript correction	participated in the planning and coordination of the study and in the manuscript correction	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Review & Editing	YES
5580439	28863779	XG	2	analysed the results	analysed the results	Analyzed the data	Formal analysis	YES
5580439	28863779	YR	2	provided the termite species for the experiments|participated in the planning and coordination of the study and in the manuscript correction	provided the termite species for the experiments	-	-	NO
5580439	28863779	YR	2	provided the termite species for the experiments|participated in the planning and coordination of the study and in the manuscript correction	participated in the planning and coordination of the study and in the manuscript correction	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Review & Editing	YES
4414413	25923662	AS	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414413	25923662	AS	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414413	25923662	AW	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414413	25923662	JN	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414413	25923662	SR	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414413	25923662	SR	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414413	25923662	VE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414413	25923662	VE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414413	25923662	VE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414413	25923662	VE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414413	25923662	VE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5845090	29523980	CS	2	acquired and analyzed the data|created the figures and drafted the article	acquired and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5845090	29523980	CS	2	acquired and analyzed the data|created the figures and drafted the article	created the figures and drafted the article	Wrote the paper	Visualization|Writing - Original Draft	YES
5845090	29523980	MK	2	acquired and analyzed the data	acquired and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5845090	29523980	YM	2	conceived and designed the present study|supervised, and oversaw the quality control, the overall project	conceived and designed the present study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5845090	29523980	YM	2	conceived and designed the present study|supervised, and oversaw the quality control, the overall project	supervised, and oversaw the quality control, the overall project	Performed the experiments	Supervision|Validation	YES
3605276	23432819	All the authors	2	contributed to and approved the final manuscript	contributed to and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4606188	26495296	Daniela Belotti	2	have contributed equally to this work as co-first author	have contributed equally to this work as co-first author	-	-	NO
4606188	26495296	Elisa Gambini	2	have contributed equally to this work as co-last author	have contributed equally to this work as co-last author	-	-	NO
4606188	26495296	Giulio Pompilio	2	have contributed equally to this work as co-last author	have contributed equally to this work as co-last author	-	-	NO
4606188	26495296	Giuseppe Gaipa	2	have contributed equally to this work as co-first author	have contributed equally to this work as co-first author	-	-	NO
3607906	23517650	A.M.	2	is responsible for research design, conducting laboratory tests, statistical analysis and manuscript preparation	is responsible for research design, conducting laboratory tests, statistical analysis and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3607906	23517650	A.R.	2	was responsible for subject recruitment and laboratory tests assistance	was responsible for subject recruitment and laboratory tests assistance	Performed the experiments	Investigation	YES
5581476	28865446	All authors	2	contributed to and approved of the final manuscript	contributed to and approved of the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5581476	28865446	CFF	2	performed the validation experiments	performed the validation experiments	Performed the experiments	Investigation|Validation	YES
5581476	28865446	DGJL	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5581476	28865446	EK	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5581476	28865446	JBP	2	collected, and performed pre- and post-processing of the data	collected, and performed pre- and post-processing of the data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5581476	28865446	NM	2	collected, and performed pre- and post-processing of the data	collected, and performed pre- and post-processing of the data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
4606191	26495308	Martina Krecmerova	2	has made substantial contributions to conception and design, acquisition, analysis, and interpretation of data, has been involved in drafting the paper, or revising it critically for important intellectual content|agrees to be accountable for all aspects of the work, ensuring that the questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	has made substantial contributions to conception and design, acquisition, analysis, and interpretation of data, has been involved in drafting the paper, or revising it critically for important intellectual content	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
4606191	26495308	Martina Krecmerova	2	has made substantial contributions to conception and design, acquisition, analysis, and interpretation of data, has been involved in drafting the paper, or revising it critically for important intellectual content|agrees to be accountable for all aspects of the work, ensuring that the questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	agrees to be accountable for all aspects of the work, ensuring that the questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	-	-	NO
4606191	26495308	Tomas Vymazal	2	has made substantial contributions to conception and design and analysis and interpretation of data, has been involved in drafting the paper and revising it critically for important intellectual content, and has given the final approval of the version to be published|agrees to be accountable for all aspects of the work, ensuring that the questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	has made substantial contributions to conception and design and analysis and interpretation of data, has been involved in drafting the paper and revising it critically for important intellectual content, and has given the final approval of the version to be published	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Resources|Writing - Original Draft|Writing - Review & Editing	YES
4606191	26495308	Tomas Vymazal	2	has made substantial contributions to conception and design and analysis and interpretation of data, has been involved in drafting the paper and revising it critically for important intellectual content, and has given the final approval of the version to be published|agrees to be accountable for all aspects of the work, ensuring that the questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	agrees to be accountable for all aspects of the work, ensuring that the questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	-	-	NO
4414415	25923332	IMS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414415	25923332	IMS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414415	25923332	IMS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414415	25923332	IMS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414415	25923332	IMS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414415	25923332	NP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414415	25923332	NP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414415	25923332	NP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1885825	17565376	BF	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1885825	17565376	BF	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1885825	17565376	BF	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1885825	17565376	DB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1885825	17565376	DB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1885825	17565376	DB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1885825	17565376	DB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1885825	17565376	FB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1885825	17565376	FB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1885825	17565376	FB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1885825	17565376	FB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1885825	17565376	FC	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1885825	17565376	FC	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1885825	17565376	GS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1885825	17565376	GS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1885825	17565376	GS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1885825	17565376	JH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1885825	17565376	JH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1885825	17565376	JH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1885825	17565376	MD	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1885825	17565376	MD	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1885825	17565376	MD	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1885825	17565376	MG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1885825	17565376	MG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1885825	17565376	MG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1885825	17565376	MH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1885825	17565376	MH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1885825	17565376	MN	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1885825	17565376	MN	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1885825	17565376	SB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1885825	17565376	SB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1885825	17565376	SB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1885825	17565376	TL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1885825	17565376	TL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1885825	17565376	TL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1885825	17565376	UM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1885825	17565376	UM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1885825	17565376	UM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1885825	17565376	UM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1885825	17565376	VO	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1885825	17565376	VO	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1885825	17565376	VO	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5712882	29238353	AA	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5712882	29238353	IP	PLoS52	conceived and designed the experiments|analyzed the data|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5712882	29238353	IP	PLoS52	conceived and designed the experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5712882	29238353	IP	PLoS52	conceived and designed the experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5712882	29238353	IS	PLoS52	analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5712882	29238353	IS	PLoS52	analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5712882	29238353	M-DT	PLoS52	performed the experiments|analyzed the data|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5712882	29238353	M-DT	PLoS52	performed the experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5712882	29238353	M-DT	PLoS52	performed the experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5869326	29589224	AC	2	carried out the pet scan acquisitions, obtained the if and tac data in all patients, implemented patlaks analysis and 5p-kma, and participated in the manuscript writing	carried out the pet scan acquisitions, obtained the if and tac data in all patients, implemented patlaks analysis and 5p-kma, and participated in the manuscript writing	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5869326	29589224	AG	2	carried out the pet scan acquisitions, obtained the if and tac data in all patients, implemented patlaks analysis and 5p-kma, and participated in the manuscript writing	carried out the pet scan acquisitions, obtained the if and tac data in all patients, implemented patlaks analysis and 5p-kma, and participated in the manuscript writing	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5869326	29589224	EL	2	conceived the 3p-kma and participated in the study design and coordination and in the manuscript writing	conceived the 3p-kma and participated in the study design and coordination and in the manuscript writing	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
5869326	29589224	GG	2	carried out the pet scan acquisitions, obtained the if and tac data in all patients, implemented patlaks analysis and 5p-kma, and participated in the manuscript writing	carried out the pet scan acquisitions, obtained the if and tac data in all patients, implemented patlaks analysis and 5p-kma, and participated in the manuscript writing	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5869326	29589224	LI	2	carried out the pet scan acquisitions, obtained the if and tac data in all patients, implemented patlaks analysis and 5p-kma, and participated in the manuscript writing	carried out the pet scan acquisitions, obtained the if and tac data in all patients, implemented patlaks analysis and 5p-kma, and participated in the manuscript writing	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5869326	29589224	MLC	2	carried out the pet scan acquisitions, obtained the if and tac data in all patients, implemented patlaks analysis and 5p-kma, and participated in the manuscript writing	carried out the pet scan acquisitions, obtained the if and tac data in all patients, implemented patlaks analysis and 5p-kma, and participated in the manuscript writing	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5869326	29589224	RM	2	participated in the study design, in the model interpretation, and in the manuscript writing	participated in the study design, in the model interpretation, and in the manuscript writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3607973	23237303	All authors	2	have written the first draft of the manuscript, revised it and approved its final version	have written the first draft of the manuscript, revised it and approved its final version	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5583987	28870167	HCL	2	conceived the study, obtained the funding, and participated in its design and coordination and helped draft the manuscript	conceived the study, obtained the funding, and participated in its design and coordination and helped draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Funding acquisition|Methodology|Project administration|Writing - Original Draft	YES
5583987	28870167	JAH	2	performed the mirna seq and rna seq data analyses, carried out the mirna target prediction/validation and yeast one-hybrid studies and helped draft the manuscript	performed the mirna seq and rna seq data analyses, carried out the mirna target prediction/validation and yeast one-hybrid studies and helped draft the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Validation|Writing - Original Draft	YES
5583987	28870167	TEP	2	participated in the design of the study, contributed to interpretation of the data and helped draft the manuscript	participated in the design of the study, contributed to interpretation of the data and helped draft the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Original Draft	YES
1885826	17565377	LM	PLoS5	Analyzed the data|Helped in conducting the study	Analyzed the data	Analyzed the data	Formal analysis	YES
1885826	17565377	LM	PLoS5	Analyzed the data|Helped in conducting the study	Helped in conducting the study	Performed the experiments	Investigation	YES
1885826	17565377	PM	PLoS5	Conceived and designed the experiments|Helped in review of literature	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1885826	17565377	PM	PLoS5	Conceived and designed the experiments|Helped in review of literature	Helped in review of literature	-	Formal analysis	YES
1885826	17565377	RS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1885826	17565377	RS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1885826	17565377	RS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1885826	17565377	RS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1885826	17565377	SG	PLoS5	Conceived and designed the experiments|Analyzed the data|Helped in writing the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1885826	17565377	SG	PLoS5	Conceived and designed the experiments|Analyzed the data|Helped in writing the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1885826	17565377	SG	PLoS5	Conceived and designed the experiments|Analyzed the data|Helped in writing the paper	Helped in writing the paper	Wrote the paper	Writing - Original Draft	YES
1885826	17565377	SP	PLoS5	Conceived and designed the experiments|Analyzed the data|Helped in writing the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1885826	17565377	SP	PLoS5	Conceived and designed the experiments|Analyzed the data|Helped in writing the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1885826	17565377	SP	PLoS5	Conceived and designed the experiments|Analyzed the data|Helped in writing the paper	Helped in writing the paper	Wrote the paper	Writing - Original Draft	YES
4414420	25924013	AN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414420	25924013	AN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414420	25924013	AN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414420	25924013	AN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414420	25924013	CL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414420	25924013	CL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414420	25924013	CL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414420	25924013	CL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414420	25924013	HC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414420	25924013	HC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414420	25924013	HC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414420	25924013	IK	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414420	25924013	IK	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414420	25924013	KM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414420	25924013	KM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414420	25924013	KM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414420	25924013	LW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414420	25924013	LW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414420	25924013	LW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414420	25924013	LW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414420	25924013	SH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414420	25924013	SH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414420	25924013	SH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414420	25924013	SM	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3610290	23497120	NL	2	conceived and designed the study and prepared the manuscript	conceived and designed the study and prepared the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
3610290	23497120	TR	2	carried out all the experimental work and statistical analysis and helped to draft the manuscript	carried out all the experimental work and statistical analysis and helped to draft the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3610290	23497120	TT	2	provided medical coverage throughout the experiment	provided medical coverage throughout the experiment	-	-	NO
3610290	23497120	YK	2	carried out all the experimental work and statistical analysis and helped to draft the manuscript	carried out all the experimental work and statistical analysis and helped to draft the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5713035	29238356	HZ	PLoS52	designed the experiments|analyzed the data	designed the experiments	Conceived and designed the experiments	Methodology	YES
5713035	29238356	HZ	PLoS52	designed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5713035	29238356	JC	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5713035	29238356	JL	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5713035	29238356	PX	PLoS52	performed the experiments|carried out the bioinformatics analyses	performed the experiments	Performed the experiments	Investigation	YES
5713035	29238356	PX	PLoS52	performed the experiments|carried out the bioinformatics analyses	carried out the bioinformatics analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5713035	29238356	QY	PLoS52	designed the experiments|analyzed the data|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5713035	29238356	QY	PLoS52	designed the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5713035	29238356	QY	PLoS52	designed the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5713035	29238356	WC	PLoS52	designed the experiments|performed the experiments|carried out the bioinformatics analyses|analyzed the data|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5713035	29238356	WC	PLoS52	designed the experiments|performed the experiments|carried out the bioinformatics analyses|analyzed the data|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5713035	29238356	WC	PLoS52	designed the experiments|performed the experiments|carried out the bioinformatics analyses|analyzed the data|wrote the manuscript	carried out the bioinformatics analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5713035	29238356	WC	PLoS52	designed the experiments|performed the experiments|carried out the bioinformatics analyses|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5713035	29238356	WC	PLoS52	designed the experiments|performed the experiments|carried out the bioinformatics analyses|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5869349	29589155	AG	2	performed surgical procedures	performed surgical procedures	Performed the experiments	Investigation	YES
5869349	29589155	JH	2	participated in the design and implementation of the study	participated in the design and implementation of the study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5869349	29589155	JM	2	performed surgical procedures	performed surgical procedures	Performed the experiments	Investigation	YES
5869349	29589155	JS	2	participated in the design and implementation of the study|carried out the histology analyses	participated in the design and implementation of the study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5869349	29589155	JS	2	participated in the design and implementation of the study|carried out the histology analyses	carried out the histology analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5869349	29589155	LPK	2	carried out the histology analyses	carried out the histology analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5869349	29589155	MD	2	contributed to the data analysis|participated in the design and implementation of the study	contributed to the data analysis	Analyzed the data	Formal analysis	YES
5869349	29589155	MD	2	contributed to the data analysis|participated in the design and implementation of the study	participated in the design and implementation of the study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5869349	29589155	MP	2	contributed to the data analysis|participated in the design and implementation of the study	contributed to the data analysis	Analyzed the data	Formal analysis	YES
5869349	29589155	MP	2	contributed to the data analysis|participated in the design and implementation of the study	participated in the design and implementation of the study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5869349	29589155	PS	2	contributed to the data analysis	contributed to the data analysis	Analyzed the data	Formal analysis	YES
5869349	29589155	TR	2	contributed to the data analysis|participated in the design and implementation of the study	contributed to the data analysis	Analyzed the data	Formal analysis	YES
5869349	29589155	TR	2	contributed to the data analysis|participated in the design and implementation of the study	participated in the design and implementation of the study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5869349	29589155	VR	2	contributed to the data analysis	contributed to the data analysis	Analyzed the data	Formal analysis	YES
5869349	29589155	XS	2	performed radiotracer syntheses	performed radiotracer syntheses	Performed the experiments	Investigation	YES
5584002	28870170	All authors	2	contributed to prepare tables and figures, edited and approved the final manuscript	contributed to prepare tables and figures, edited and approved the final manuscript	Wrote the paper	Visualization|Writing - Original Draft|Writing - Review & Editing	YES
5584002	28870170	BFM	2	acted as a scientific consultant	acted as a scientific consultant	-	-	NO
5584002	28870170	BM	2	identified and analyzed plant cell wall degrading enzymes	identified and analyzed plant cell wall degrading enzymes	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5584002	28870170	SL	2	conceived and led the project, prepared fungal culture and dna for sequencing|wrote the manuscript	conceived and led the project, prepared fungal culture and dna for sequencing	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5584002	28870170	SL	2	conceived and led the project, prepared fungal culture and dna for sequencing|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3614480	23537142	AC	2	conceived the study|developed the design of the study|recruited participants, screened participants, collected all data, developed all sport drinks tested, performed statistical analyses, and wrote the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
3614480	23537142	AC	2	conceived the study|developed the design of the study|recruited participants, screened participants, collected all data, developed all sport drinks tested, performed statistical analyses, and wrote the manuscript	developed the design of the study	Conceived and designed the experiments	Methodology	YES
3614480	23537142	AC	2	conceived the study|developed the design of the study|recruited participants, screened participants, collected all data, developed all sport drinks tested, performed statistical analyses, and wrote the manuscript	recruited participants, screened participants, collected all data, developed all sport drinks tested, performed statistical analyses, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3614480	23537142	DL	2	contributed to the study design and helped draft the manuscript	contributed to the study design and helped draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3614480	23537142	HR	2	developed the design of the study|helped to draft the manuscript	developed the design of the study	Conceived and designed the experiments	Methodology	YES
3614480	23537142	HR	2	developed the design of the study|helped to draft the manuscript	helped to draft the manuscript	Wrote the paper	Writing - Original Draft	YES
1885827	17565381	AJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1885827	17565381	AJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1885827	17565381	AJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1885827	17565381	AJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1885827	17565381	AJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1885827	17565381	AW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1885827	17565381	AW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1885827	17565381	AW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1885827	17565381	AW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1885827	17565381	AW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1885827	17565381	BR	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1885827	17565381	CF	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1885827	17565381	HL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1885827	17565381	KW	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1885827	17565381	LP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1885827	17565381	MH	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1885827	17565381	MH	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1885827	17565381	MK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1885827	17565381	MR	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1885827	17565381	MS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1885827	17565381	PM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1885827	17565381	RG	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1885827	17565381	SV	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1885827	17565381	UH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1885827	17565381	WH	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1885827	17565381	YW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4414421	25923107	AMC	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414421	25923107	AMC	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414421	25923107	DSW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414421	25923107	DSW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414421	25923107	DSW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414421	25923107	DSW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414421	25923107	FS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414421	25923107	FS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414421	25923107	HWH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414421	25923107	HWH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4414421	25923107	HWH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4414421	25923107	JTM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414421	25923107	JTM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414421	25923107	JTM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414421	25923107	JTM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414421	25923107	KR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414421	25923107	KR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414421	25923107	KR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414421	25923107	KR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414421	25923107	KRC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414421	25923107	KRC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414421	25923107	MKK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414421	25923107	MKK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414421	25923107	MKK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414421	25923107	MKK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414421	25923107	MT	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4414421	25923107	RAM	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414421	25923107	RAM	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414421	25923107	RRC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414421	25923107	RRC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414421	25923107	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414421	25923107	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4414421	25923107	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4414421	25923107	TJC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414421	25923107	TJC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414421	25923107	TJC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414421	25923107	TJC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5874225	29594931	EFS	2	contributed to the design, critical review and revision of the manuscript	contributed to the design, critical review and revision of the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Review & Editing	YES
5874225	29594931	GMK	2	contributed to the data acquisition and analysis, critical review and revision of the manuscript	contributed to the data acquisition and analysis, critical review and revision of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
5874225	29594931	OSH	2	contributed to the concept, design, critical review and revision of the manuscript	contributed to the concept, design, critical review and revision of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5874225	29594931	RB	2	contributed to the concept, design, data-analysis and interpretation, drafting and revision of the manuscript	contributed to the concept, design, data-analysis and interpretation, drafting and revision of the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5874225	29594931	RI	2	contributed to the concept, design, data-analysis and interpretation, drafting and revision of the manuscript	contributed to the concept, design, data-analysis and interpretation, drafting and revision of the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5874225	29594931	VF	2	contributed to the data acquisition and analysis, critical review and revision of the manuscript	contributed to the data acquisition and analysis, critical review and revision of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
5714861	29250099	FA	2	performed the data analysis|wrote the manuscript	performed the data analysis	Analyzed the data	Formal analysis	YES
5714861	29250099	FA	2	performed the data analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5714861	29250099	HG	2	performed the data analysis|wrote the manuscript	performed the data analysis	Analyzed the data	Formal analysis	YES
5714861	29250099	HG	2	performed the data analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5714861	29250099	QP	2	designed this study|performed the data analysis|wrote the manuscript	designed this study	Conceived and designed the experiments	Methodology	YES
5714861	29250099	QP	2	designed this study|performed the data analysis|wrote the manuscript	performed the data analysis	Analyzed the data	Formal analysis	YES
5714861	29250099	QP	2	designed this study|performed the data analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3618008	23552612	AM	2	participated in data collection, statistical analysis	participated in data collection, statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3618008	23552612	GD	2	served as the principal investigator and contributed to study design, data collection, and manuscript preparation	served as the principal investigator and contributed to study design, data collection, and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Funding acquisition|Investigation|Methodology|Resources|Writing - Original Draft	YES
3618008	23552612	LB	2	participated in statistical analysis and manuscript preparation	participated in statistical analysis and manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5584012	28870171	AEM	2	analysed data	analysed data	Analyzed the data	Formal analysis	YES
5584012	28870171	AK	2	provided isolates and materials	provided isolates and materials	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5584012	28870171	AM	2	provided isolates and materials	provided isolates and materials	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5584012	28870171	DJ	2	designed the study|analysed data|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5584012	28870171	DJ	2	designed the study|analysed data|wrote the manuscript	analysed data	Analyzed the data	Formal analysis	YES
5584012	28870171	DJ	2	designed the study|analysed data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5584012	28870171	EMH	2	designed the study|analysed data	designed the study	Conceived and designed the experiments	Methodology	YES
5584012	28870171	EMH	2	designed the study|analysed data	analysed data	Analyzed the data	Formal analysis	YES
5584012	28870171	FC	2	analysed data	analysed data	Analyzed the data	Formal analysis	YES
5584012	28870171	JP	2	provided isolates and materials|supervised and managed the study	provided isolates and materials	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5584012	28870171	JP	2	provided isolates and materials|supervised and managed the study	supervised and managed the study	-	Project administration|Supervision	YES
5584012	28870171	MET	2	provided isolates and materials	provided isolates and materials	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5584012	28870171	SJP	2	designed the study|provided isolates and materials|supervised and managed the study|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5584012	28870171	SJP	2	designed the study|provided isolates and materials|supervised and managed the study|wrote the manuscript	provided isolates and materials	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5584012	28870171	SJP	2	designed the study|provided isolates and materials|supervised and managed the study|wrote the manuscript	supervised and managed the study	-	Project administration|Supervision	YES
5584012	28870171	SJP	2	designed the study|provided isolates and materials|supervised and managed the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5584012	28870171	SRH	2	developed the computational analysis tools	developed the computational analysis tools	Analyzed the data	Formal analysis	YES
5584012	28870171	TE	2	provided isolates and materials	provided isolates and materials	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4606217	26495310	Xiaowen Chen	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
4606217	26495310	Yanqiu Wang	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
1885828	17565383	RM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1885828	17565383	RM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1885828	17565383	RM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1885828	17565383	RM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1885828	17565383	SS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1885828	17565383	SS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1885828	17565383	SS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4747948	26860613	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4747948	26860613	JB	2	planned and executed the experiments, collected and calculated all data, created the graphs and figures and drafted this manuscript	planned and executed the experiments, collected and calculated all data, created the graphs and figures and drafted this manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Visualization|Writing - Original Draft	YES
4747948	26860613	MH	2	significantly contributed to data evaluation and interpretation of the experiment	significantly contributed to data evaluation and interpretation of the experiment	Analyzed the data	Formal analysis	YES
4747948	26860613	RH	2	substantially contributed to conception and design of the conducted experiments	substantially contributed to conception and design of the conducted experiments	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
3620959	23537169	All authors	2	contributed to the study design, the muscle and blood collection procedure, biochemical analyses, statistical analysis, and preparation of the manuscript	contributed to the study design, the muscle and blood collection procedure, biochemical analyses, statistical analysis, and preparation of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4414448	25923817	CMH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414448	25923817	CMH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414448	25923817	CMH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414448	25923817	CMH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414448	25923817	CMH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414448	25923817	FHA	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414448	25923817	FHA	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4414448	25923817	FHA	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414448	25923817	HB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4414448	25923817	HB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4414448	25923817	HB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414448	25923817	JKK	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4414448	25923817	JKK	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4414448	25923817	JKK	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414448	25923817	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414448	25923817	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414448	25923817	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414448	25923817	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414448	25923817	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414448	25923817	MKJ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4414448	25923817	MKJ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4414448	25923817	MKJ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414448	25923817	OH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4414448	25923817	OH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4414448	25923817	OH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414448	25923817	PLH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414448	25923817	PLH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414448	25923817	PLH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414448	25923817	PLH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414448	25923817	TP	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4414448	25923817	TP	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4414448	25923817	TP	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5714865	29250095	BY	PLoS52	prepared the samples	prepared the samples	Performed the experiments	Investigation	YES
5714865	29250095	CZ	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5714865	29250095	FW	PLoS52	prepared the samples	prepared the samples	Performed the experiments	Investigation	YES
5714865	29250095	JX	PLoS52	conceived the experiments and revised the manuscript	conceived the experiments and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5714865	29250095	KY	PLoS52	conceived the experiments and revised the manuscript	conceived the experiments and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5714865	29250095	LH	PLoS52	designed and performed the experiments, and prepared the manuscript	designed and performed the experiments, and prepared the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5714865	29250095	YnG	PLoS52	designed and performed the experiments, and prepared the manuscript	designed and performed the experiments, and prepared the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5714865	29250095	YqG	PLoS52	prepared the samples	prepared the samples	Performed the experiments	Investigation	YES
5714865	29250095	ZL	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5882477	29616369	AC	2	performed the statistical analysis of the pet and mri data, discussed the results, and revised the manuscript	performed the statistical analysis of the pet and mri data, discussed the results, and revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5882477	29616369	ES	2	designed and managed the study, discussed the results, and revised the manuscript	designed and managed the study, discussed the results, and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Review & Editing	YES
5882477	29616369	HR	2	provided the mmtv pymt animal model and discussed the results	provided the mmtv pymt animal model and discussed the results	Performed the experiments	Methodology	YES
5882477	29616369	LL	2	performed the pet data acquisition and analysis	performed the pet data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5882477	29616369	PD	2	carried out the mr imaging experiments and participated in the study discussion	carried out the mr imaging experiments and participated in the study discussion	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
5882477	29616369	RVK	2	performed the histology/immunohistochemistry studies, data analysis, and the manuscript revision	performed the histology/immunohistochemistry studies, data analysis, and the manuscript revision	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
5882477	29616369	SE	2	performed the statistical analysis of the pet and mri data, discussed the results, and revised the manuscript	performed the statistical analysis of the pet and mri data, discussed the results, and revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5882477	29616369	SH	2	coordinated the study and revised the manuscript	coordinated the study and revised the manuscript	Wrote the paper	Project administration|Writing - Review & Editing	YES
5882477	29616369	SNA	2	carried out the mr imaging experiments and participated in the study discussion	carried out the mr imaging experiments and participated in the study discussion	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
5882477	29616369	TF	2	was involved in the study treatment planning	was involved in the study treatment planning	Conceived and designed the experiments	Methodology	YES
5882477	29616369	TT	2	managed the study, performed pet data analysis, discussed the results, and drafted the manuscript	managed the study, performed pet data analysis, discussed the results, and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Formal analysis|Investigation|Project administration|Writing - Original Draft	YES
3623621	23432855	All	2	authors participated in writing, editing and approval of the final manuscript	authors participated in writing, editing and approval of the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3623621	23432855	EJHL	2	participated in study conception and design|performed data collection	participated in study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
3623621	23432855	EJHL	2	participated in study conception and design|performed data collection	performed data collection	Performed the experiments	Investigation	YES
3623621	23432855	GDW	2	participated in study conception and design|authors participated in writing, editing and approval of the final manuscript	participated in study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
3623621	23432855	GDW	2	participated in study conception and design|authors participated in writing, editing and approval of the final manuscript	authors participated in writing, editing and approval of the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3623621	23432855	SGT	2	participated in study conception and design|authors participated in writing, editing and approval of the final manuscript	participated in study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
3623621	23432855	SGT	2	participated in study conception and design|authors participated in writing, editing and approval of the final manuscript	authors participated in writing, editing and approval of the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3623621	23432855	SJF	2	performed data collection	performed data collection	Performed the experiments	Investigation	YES
1885829	17565382	HW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1885829	17565382	HW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1885829	17565382	HW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1885829	17565382	HW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1885829	17565382	MM	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1885829	17565382	MM	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3835358	24302878	Eugenia Castro-Mussot	2	supervised the project and edited the paper	supervised the project and edited the paper	Wrote the paper	Supervision|Writing - Review & Editing	YES
3835358	24302878	Griselda Ramirez-Reyes	2	performed the surgeries and selected and collected the cns tissue	performed the surgeries and selected and collected the cns tissue	Performed the experiments	Investigation	YES
3835358	24302878	Leticia Cedillo-Barron	2	obtained and evaluated the anti-ns3 monoclonal antibody used to detect viral replication	obtained and evaluated the anti-ns3 monoclonal antibody used to detect viral replication	Performed the experiments	Investigation|Validation	YES
3835358	24302878	Ma Isabel Salazar	2	supervised the entire development of the project, wrote the paper, and carried out the submission and revision processes	supervised the entire development of the project, wrote the paper, and carried out the submission and revision processes	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
3835358	24302878	Marisol Terreros-Tinoco	2	carried out the coimmunoprecipitation assays	carried out the coimmunoprecipitation assays	Performed the experiments	Investigation	YES
3835358	24302878	Marissa Perez-Garcia	2	established the primary-cns cultures and performed the vopba and immunofluorescence assays	established the primary-cns cultures and performed the vopba and immunofluorescence assays	Performed the experiments	Investigation	YES
3835358	24302878	Martha Garcia-Flores	2	outlined the initial project, established the collaboration, and analyzed the results	outlined the initial project, established the collaboration, and analyzed the results	Analyzed the data	Formal analysis	YES
3835358	24302878	Penelope Aguilera	2	supervised the staining procedures and set up the cell markers system	supervised the staining procedures and set up the cell markers system	Performed the experiments	Investigation|Methodology|Supervision	YES
5584319	28870149	HB	2	performed the genotyping	performed the genotyping	Performed the experiments	Investigation	YES
5584319	28870149	HL	2	performed the genotyping	performed the genotyping	Performed the experiments	Investigation	YES
5584319	28870149	HZ	2	developed the markers, assisted with manuscript editing, and design the study	developed the markers, assisted with manuscript editing, and design the study	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5584319	28870149	LZ	2	processed the resequencing data, analyzed the genomic variation, and constructed the phylogenetic tree	processed the resequencing data, analyzed the genomic variation, and constructed the phylogenetic tree	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5584319	28870149	MG	2	helped analyze the data	helped analyze the data	Analyzed the data	Formal analysis	YES
5584319	28870149	SL	2	performed the genotyping	performed the genotyping	Performed the experiments	Investigation	YES
5584319	28870149	TZ	2	performed the genotyping, analyzed the population structure, constructed the phylogenetic tree, assessed the genetic diversity and differentiation, selected the core set, and wrote the manuscript	performed the genotyping, analyzed the population structure, constructed the phylogenetic tree, assessed the genetic diversity and differentiation, selected the core set, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5584319	28870149	YL	2	polished the paper|processed the resequencing data, analyzed the genomic variation, and constructed the phylogenetic tree	polished the paper	Wrote the paper	Writing - Review & Editing	YES
5584319	28870149	YL	2	polished the paper|processed the resequencing data, analyzed the genomic variation, and constructed the phylogenetic tree	processed the resequencing data, analyzed the genomic variation, and constructed the phylogenetic tree	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
3623762	23531361	CAW	2	interpreted the data and reviewed the manuscript	interpreted the data and reviewed the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
3623762	23531361	MT	2	designed the study|were involved in statistical analysis and drafted the manuscript|interpreted the data and reviewed the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
3623762	23531361	MT	2	designed the study|were involved in statistical analysis and drafted the manuscript|interpreted the data and reviewed the manuscript	were involved in statistical analysis and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3623762	23531361	MT	2	designed the study|were involved in statistical analysis and drafted the manuscript|interpreted the data and reviewed the manuscript	interpreted the data and reviewed the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
3623762	23531361	SF	2	interpreted the data and reviewed the manuscript	interpreted the data and reviewed the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
3623762	23531361	SMG	2	designed the study|were involved in data collection|were involved in statistical analysis and drafted the manuscript|interpreted the data and reviewed the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
3623762	23531361	SMG	2	designed the study|were involved in data collection|were involved in statistical analysis and drafted the manuscript|interpreted the data and reviewed the manuscript	were involved in data collection	Performed the experiments	Investigation	YES
3623762	23531361	SMG	2	designed the study|were involved in data collection|were involved in statistical analysis and drafted the manuscript|interpreted the data and reviewed the manuscript	were involved in statistical analysis and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3623762	23531361	SMG	2	designed the study|were involved in data collection|were involved in statistical analysis and drafted the manuscript|interpreted the data and reviewed the manuscript	interpreted the data and reviewed the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
3623762	23531361	SMM	2	designed the study|were involved in data collection|were involved in statistical analysis and drafted the manuscript|interpreted the data and reviewed the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
3623762	23531361	SMM	2	designed the study|were involved in data collection|were involved in statistical analysis and drafted the manuscript|interpreted the data and reviewed the manuscript	were involved in data collection	Performed the experiments	Investigation	YES
3623762	23531361	SMM	2	designed the study|were involved in data collection|were involved in statistical analysis and drafted the manuscript|interpreted the data and reviewed the manuscript	were involved in statistical analysis and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3623762	23531361	SMM	2	designed the study|were involved in data collection|were involved in statistical analysis and drafted the manuscript|interpreted the data and reviewed the manuscript	interpreted the data and reviewed the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
3623762	23531361	UB	2	interpreted the data and reviewed the manuscript	interpreted the data and reviewed the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4414449	25923431	HS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4414449	25923431	ICM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414449	25923431	KT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Prediction of functional motif	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414449	25923431	KT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Prediction of functional motif	Performed the experiments	Performed the experiments	Investigation	YES
4414449	25923431	KT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Prediction of functional motif	Analyzed the data	Analyzed the data	Formal analysis	YES
4414449	25923431	KT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Prediction of functional motif	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414449	25923431	KT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Prediction of functional motif	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414449	25923431	KT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Prediction of functional motif	Prediction of functional motif	Analyzed the data	Formal analysis	YES
4414449	25923431	MI	PLoS5	Prediction of functional motif	Prediction of functional motif	Analyzed the data	Formal analysis	YES
4414449	25923431	MT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Prediction of functional motif	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414449	25923431	MT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Prediction of functional motif	Performed the experiments	Performed the experiments	Investigation	YES
4414449	25923431	MT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Prediction of functional motif	Analyzed the data	Analyzed the data	Formal analysis	YES
4414449	25923431	MT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Prediction of functional motif	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414449	25923431	MT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Prediction of functional motif	Prediction of functional motif	Analyzed the data	Formal analysis	YES
4414449	25923431	TM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414449	25923431	YK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414449	25923431	YK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4414449	25923431	YK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5884746	29619584	AG	2	carried out the study design and coordination, and drafted the manuscript	carried out the study design and coordination, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Project administration|Writing - Original Draft	YES
5884746	29619584	DS	2	participated in the elisa assay and edited the manuscript	participated in the elisa assay and edited the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5884746	29619584	JK	2	participated in the interpretation of data and revision of the manuscript	participated in the interpretation of data and revision of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5884746	29619584	YA	2	participated in the study design, carried out the animal study and imaging, processed the data, conducted the elisa assay, and drafted the manuscript	participated in the study design, carried out the animal study and imaging, processed the data, conducted the elisa assay, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Investigation|Methodology|Visualization|Writing - Original Draft	YES
5714882	29250094	A-MW	2	cultivated the plants and prepared plant extracts|who also wrote the manuscript with	cultivated the plants and prepared plant extracts	Performed the experiments	Investigation	YES
5714882	29250094	A-MW	2	cultivated the plants and prepared plant extracts|who also wrote the manuscript with	who also wrote the manuscript with	Wrote the paper	Writing - Original Draft	YES
5714882	29250094	DO	2	assisted a-mw who also wrote the manuscript with	assisted a-mw who also wrote the manuscript with	Wrote the paper	Writing - Original Draft	YES
5714882	29250094	KS	2	assisted a-mw who also wrote the manuscript with	assisted a-mw who also wrote the manuscript with	Wrote the paper	Writing - Original Draft	YES
5714882	29250094	TD	2	assisted a-mw who also wrote the manuscript with	assisted a-mw who also wrote the manuscript with	Wrote the paper	Writing - Original Draft	YES
5714882	29250094	The authors	2	would also like to acknowledge the help of a professional editing service	would also like to acknowledge the help of a professional editing service	Wrote the paper	Writing - Review & Editing	YES
1885830	17565385	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1885830	17565385	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1885830	17565385	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1885830	17565385	BS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1885830	17565385	JW	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1885830	17565385	MD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1885830	17565385	MD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1885830	17565385	MD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1885830	17565385	MD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1885830	17565385	MD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1885830	17565385	ME	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1885830	17565385	MP	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1885830	17565385	MP	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1885830	17565385	PK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1885830	17565385	PK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1885830	17565385	PK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1885830	17565385	PK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1885830	17565385	PK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3626726	23566489	AP	2	assisted in research design and analysis	assisted in research design and analysis	Conceived and designed the experiments	-	YES
3626726	23566489	CC	2	were involved in research design, analysis and manuscript preparation	were involved in research design, analysis and manuscript preparation	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
3626726	23566489	DM	2	were involved in research design, analysis and manuscript preparation	were involved in research design, analysis and manuscript preparation	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
3626726	23566489	FD	2	assisted in research design and analysis	assisted in research design and analysis	Conceived and designed the experiments	-	YES
3626726	23566489	JAT	2	assisted in research design and analysis	assisted in research design and analysis	Conceived and designed the experiments	-	YES
3626726	23566489	JR	2	were the study coordinators and were involved in research design, data collection and analysis, as well as manuscript preparation	were the study coordinators and were involved in research design, data collection and analysis, as well as manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Project administration|Writing - Original Draft	YES
3626726	23566489	VP	2	were the study coordinators and were involved in research design, data collection and analysis, as well as manuscript preparation	were the study coordinators and were involved in research design, data collection and analysis, as well as manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Project administration|Writing - Original Draft	YES
4414450	25923105	ADP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Assisted in the development of the sensitivity analysis|Assisted in the design of the study, interpretation of results, and discussion of the findings	Analyzed the data	Analyzed the data	Formal analysis	YES
4414450	25923105	ADP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Assisted in the development of the sensitivity analysis|Assisted in the design of the study, interpretation of results, and discussion of the findings	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414450	25923105	ADP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Assisted in the development of the sensitivity analysis|Assisted in the design of the study, interpretation of results, and discussion of the findings	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414450	25923105	ADP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Assisted in the development of the sensitivity analysis|Assisted in the design of the study, interpretation of results, and discussion of the findings	Assisted in the development of the sensitivity analysis	-	-	NO
4414450	25923105	ADP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Assisted in the development of the sensitivity analysis|Assisted in the design of the study, interpretation of results, and discussion of the findings	Assisted in the design of the study, interpretation of results, and discussion of the findings	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
4414450	25923105	EHK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Developed the mathematical model|Assisted in the design of the study, interpretation of results, and discussion of the findings	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414450	25923105	EHK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Developed the mathematical model|Assisted in the design of the study, interpretation of results, and discussion of the findings	Analyzed the data	Analyzed the data	Formal analysis	YES
4414450	25923105	EHK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Developed the mathematical model|Assisted in the design of the study, interpretation of results, and discussion of the findings	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414450	25923105	EHK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Developed the mathematical model|Assisted in the design of the study, interpretation of results, and discussion of the findings	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414450	25923105	EHK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Developed the mathematical model|Assisted in the design of the study, interpretation of results, and discussion of the findings	Developed the mathematical model	Performed the experiments	Formal analysis|Methodology	YES
4414450	25923105	EHK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Developed the mathematical model|Assisted in the design of the study, interpretation of results, and discussion of the findings	Assisted in the design of the study, interpretation of results, and discussion of the findings	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
4414450	25923105	GSG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Had the idea for the study, assembled the survey data, implemented the model for numerical analysis, and drafted the paper|Assisted in the design of the study, interpretation of results, and discussion of the findings	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414450	25923105	GSG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Had the idea for the study, assembled the survey data, implemented the model for numerical analysis, and drafted the paper|Assisted in the design of the study, interpretation of results, and discussion of the findings	Performed the experiments	Performed the experiments	Investigation	YES
4414450	25923105	GSG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Had the idea for the study, assembled the survey data, implemented the model for numerical analysis, and drafted the paper|Assisted in the design of the study, interpretation of results, and discussion of the findings	Analyzed the data	Analyzed the data	Formal analysis	YES
4414450	25923105	GSG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Had the idea for the study, assembled the survey data, implemented the model for numerical analysis, and drafted the paper|Assisted in the design of the study, interpretation of results, and discussion of the findings	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414450	25923105	GSG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Had the idea for the study, assembled the survey data, implemented the model for numerical analysis, and drafted the paper|Assisted in the design of the study, interpretation of results, and discussion of the findings	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414450	25923105	GSG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Had the idea for the study, assembled the survey data, implemented the model for numerical analysis, and drafted the paper|Assisted in the design of the study, interpretation of results, and discussion of the findings	Had the idea for the study, assembled the survey data, implemented the model for numerical analysis, and drafted the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4414450	25923105	GSG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Had the idea for the study, assembled the survey data, implemented the model for numerical analysis, and drafted the paper|Assisted in the design of the study, interpretation of results, and discussion of the findings	Assisted in the design of the study, interpretation of results, and discussion of the findings	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
1885976	17565375	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1885976	17565375	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1885976	17565375	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1885976	17565375	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1885976	17565375	KM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1885976	17565375	KM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1885976	17565375	KM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1885976	17565375	KM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5584320	28870156	AO	2	performed the transcriptome analysis of the metabolic genes|were the main coordinators of the chrysanthemum est project	performed the transcriptome analysis of the metabolic genes	Performed the experiments	Investigation	YES
5584320	28870156	AO	2	performed the transcriptome analysis of the metabolic genes|were the main coordinators of the chrysanthemum est project	were the main coordinators of the chrysanthemum est project	-	Project administration	YES
5584320	28870156	HK	2	performed the 454 sequencing	performed the 454 sequencing	Performed the experiments	Investigation	YES
5584320	28870156	K. Kishimoto	2	performed the transcriptome analysis of the metabolic genes	performed the transcriptome analysis of the metabolic genes	Performed the experiments	Investigation	YES
5584320	28870156	KN	2	performed the transcriptome analysis of tf genes|conducted the bioinformatics analysis	performed the transcriptome analysis of tf genes	Performed the experiments	Investigation	YES
5584320	28870156	KN	2	performed the transcriptome analysis of tf genes|conducted the bioinformatics analysis	conducted the bioinformatics analysis	Performed the experiments	Formal analysis|Investigation	YES
5584320	28870156	KS	2	prepared the cdna libraries for 454 sequencing|performed the transcriptome analysis of tf genes|were the main coordinators of the chrysanthemum est project|was primarily responsible for drafting the manuscript	prepared the cdna libraries for 454 sequencing	Performed the experiments	Investigation	YES
5584320	28870156	KS	2	prepared the cdna libraries for 454 sequencing|performed the transcriptome analysis of tf genes|were the main coordinators of the chrysanthemum est project|was primarily responsible for drafting the manuscript	performed the transcriptome analysis of tf genes	Performed the experiments	Investigation	YES
5584320	28870156	KS	2	prepared the cdna libraries for 454 sequencing|performed the transcriptome analysis of tf genes|were the main coordinators of the chrysanthemum est project|was primarily responsible for drafting the manuscript	were the main coordinators of the chrysanthemum est project	-	Project administration	YES
5584320	28870156	KS	2	prepared the cdna libraries for 454 sequencing|performed the transcriptome analysis of tf genes|were the main coordinators of the chrysanthemum est project|was primarily responsible for drafting the manuscript	was primarily responsible for drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
5584320	28870156	NM	2	performed the transcriptome analysis of tf genes|conducted the bioinformatics analysis	performed the transcriptome analysis of tf genes	Performed the experiments	Investigation	YES
5584320	28870156	NM	2	performed the transcriptome analysis of tf genes|conducted the bioinformatics analysis	conducted the bioinformatics analysis	Performed the experiments	Formal analysis|Investigation	YES
5714883	29250092	AD	2	conducted the experiments	conducted the experiments	Performed the experiments	Investigation	YES
5714883	29250092	All authors	2	approved the final version of the manuscript	approved the final version of the manuscript	-	-	NO
5714883	29250092	BB	2	conducted the experiments	conducted the experiments	Performed the experiments	Investigation	YES
5714883	29250092	BS	2	conducted the experiments|produced the graphical outputs	conducted the experiments	Performed the experiments	Investigation	YES
5714883	29250092	BS	2	conducted the experiments|produced the graphical outputs	produced the graphical outputs	-	-	NO
5714883	29250092	GV	2	conducted the experiments	conducted the experiments	Performed the experiments	Investigation	YES
5714883	29250092	HvdB	2	coordinating the research work	coordinating the research work	Performed the experiments	Investigation|Project administration	YES
5714883	29250092	MM	2	conducted the experiments|conducted the data analysis|produced the graphical outputs	conducted the experiments	Performed the experiments	Investigation	YES
5714883	29250092	MM	2	conducted the experiments|conducted the data analysis|produced the graphical outputs	conducted the data analysis	Analyzed the data	Formal analysis	YES
5714883	29250092	MM	2	conducted the experiments|conducted the data analysis|produced the graphical outputs	produced the graphical outputs	-	-	NO
5714883	29250092	MvdG	2	conducted the experiments	conducted the experiments	Performed the experiments	Investigation	YES
3639826	23601452	AAF	2	assisted in analysis and interpretation of data, as well as manuscript preparation	assisted in analysis and interpretation of data, as well as manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3639826	23601452	All authors	2	participated in editing and approved the final draft of the manuscript	participated in editing and approved the final draft of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3639826	23601452	HLL	2	contributed to the design and coordination of the study, drafting the manuscript, as well as oversight of data collection and analyses	contributed to the design and coordination of the study, drafting the manuscript, as well as oversight of data collection and analyses	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Project administration|Resources|Supervision|Writing - Original Draft	YES
3639826	23601452	JEH	2	carried out the practical aspects of the study, including data collection and dietary analyses	carried out the practical aspects of the study, including data collection and dietary analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3639826	23601452	JPW	2	performed the statistical analyses	performed the statistical analyses	Analyzed the data	Formal analysis	YES
3639826	23601452	SMA	2	participated in the adipokine analyses and assisted in manuscript preparation	participated in the adipokine analyses and assisted in manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3639826	23601452	SMH	2	carried out the practical aspects of the study, including data collection and dietary analyses	carried out the practical aspects of the study, including data collection and dietary analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3639826	23601452	TNZ	2	contributed to the design and coordination of the study, drafting the manuscript, as well as oversight of data collection and analyses	contributed to the design and coordination of the study, drafting the manuscript, as well as oversight of data collection and analyses	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Project administration|Resources|Supervision|Writing - Original Draft	YES
5884747	29619657	ACB	PLoS52	designed the study|performed the experiments	designed the study	Conceived and designed the experiments	Methodology	YES
5884747	29619657	ACB	PLoS52	designed the study|performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5884747	29619657	ASC	PLoS52	designed the study|performed the experiments	designed the study	Conceived and designed the experiments	Methodology	YES
5884747	29619657	ASC	PLoS52	designed the study|performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5884747	29619657	EJ	PLoS52	developed the radiochemistry for the study|performed the experiments	developed the radiochemistry for the study	-	-	NO
5884747	29619657	EJ	PLoS52	developed the radiochemistry for the study|performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5884747	29619657	KPT	PLoS52	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
1885978	17565374	CA	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1885978	17565374	CA	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1885978	17565374	NA	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1885978	17565374	NA	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1885978	17565374	NA	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3639860	23617897	All authors	2	have made substantive intellectual contributions towards conducting the study and preparing the manuscript for publication	have made substantive intellectual contributions towards conducting the study and preparing the manuscript for publication	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3639860	23617897	GZ	2	were responsible for the study design, coordination of the study, and oversight of data collection and analysis	were responsible for the study design, coordination of the study, and oversight of data collection and analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology|Project administration|Supervision	YES
3639860	23617897	HA	2	were responsible for the study design, coordination of the study, and oversight of data collection and analysis	were responsible for the study design, coordination of the study, and oversight of data collection and analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology|Project administration|Supervision	YES
3639860	23617897	JK	2	were responsible for the study design, coordination of the study, and oversight of data collection and analysis	were responsible for the study design, coordination of the study, and oversight of data collection and analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology|Project administration|Supervision	YES
3639860	23617897	KS	2	were responsible for the study design, coordination of the study, and oversight of data collection and analysis	were responsible for the study design, coordination of the study, and oversight of data collection and analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology|Project administration|Supervision	YES
3639860	23617897	MRJ	2	were responsible for the study design, coordination of the study, and oversight of data collection and analysis	were responsible for the study design, coordination of the study, and oversight of data collection and analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology|Project administration|Supervision	YES
3639860	23617897	SRS	2	assisted in manuscript preparation and the revision of final manuscript	assisted in manuscript preparation and the revision of final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3639860	23617897	TK	2	were responsible for the study design, coordination of the study, and oversight of data collection and analysis	were responsible for the study design, coordination of the study, and oversight of data collection and analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology|Project administration|Supervision	YES
3639860	23617897	ZKM	2	were responsible for the study design, coordination of the study, and oversight of data collection and analysis	were responsible for the study design, coordination of the study, and oversight of data collection and analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology|Project administration|Supervision	YES
5714885	29250086	LB	2	performed the segregation experiment	performed the segregation experiment	Performed the experiments	Investigation	YES
5714885	29250086	R-FG	2	supervised the experiments and complemented the writing	supervised the experiments and complemented the writing	Wrote the paper	Supervision	YES
5714885	29250086	X-MG	2	planted and managed the experimental materials, designed the experiments, collected images, analyzed the data and wrote the article	planted and managed the experimental materials, designed the experiments, collected images, analyzed the data and wrote the article	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Formal analysis|Investigation|Methodology|Visualization|Writing - Original Draft	YES
4761362	26897534	AF	2	helped with the wrote the manuscript with the|were involved in analyzing the data, interpretation of the data, and reviewing the manuscript	helped with the wrote the manuscript with the	Wrote the paper	Writing - Original Draft	YES
4761362	26897534	AF	2	helped with the wrote the manuscript with the|were involved in analyzing the data, interpretation of the data, and reviewing the manuscript	were involved in analyzing the data, interpretation of the data, and reviewing the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4761362	26897534	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4761362	26897534	HD	2	analyzed the experimental data	analyzed the experimental data	Analyzed the data	Formal analysis	YES
4761362	26897534	JS	2	designed the experiments|helped with the wrote the manuscript with the	designed the experiments	Conceived and designed the experiments	Methodology	YES
4761362	26897534	JS	2	designed the experiments|helped with the wrote the manuscript with the	helped with the wrote the manuscript with the	Wrote the paper	Writing - Original Draft	YES
4761362	26897534	PP	2	designed the experiments|wrote the manuscript with the	designed the experiments	Conceived and designed the experiments	Methodology	YES
4761362	26897534	PP	2	designed the experiments|wrote the manuscript with the	wrote the manuscript with the	Wrote the paper	Writing - Original Draft	YES
4761362	26897534	RJ	2	were involved in analyzing the data, interpretation of the data, and reviewing the manuscript	were involved in analyzing the data, interpretation of the data, and reviewing the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5584376	28870168	CD	PLoS52	designed the experiments|gathered the data	designed the experiments	Conceived and designed the experiments	Methodology	YES
5584376	28870168	CD	PLoS52	designed the experiments|gathered the data	gathered the data	Performed the experiments	Investigation	YES
5584376	28870168	EH	PLoS52	designed the experiments|obtained grant support for the work|gathered the data|analyzed the data|drafted the manuscript|edited the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5584376	28870168	EH	PLoS52	designed the experiments|obtained grant support for the work|gathered the data|analyzed the data|drafted the manuscript|edited the manuscript	obtained grant support for the work	-	Funding acquisition	YES
5584376	28870168	EH	PLoS52	designed the experiments|obtained grant support for the work|gathered the data|analyzed the data|drafted the manuscript|edited the manuscript	gathered the data	Performed the experiments	Investigation	YES
5584376	28870168	EH	PLoS52	designed the experiments|obtained grant support for the work|gathered the data|analyzed the data|drafted the manuscript|edited the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5584376	28870168	EH	PLoS52	designed the experiments|obtained grant support for the work|gathered the data|analyzed the data|drafted the manuscript|edited the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5584376	28870168	EH	PLoS52	designed the experiments|obtained grant support for the work|gathered the data|analyzed the data|drafted the manuscript|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5584376	28870168	RL	PLoS52	designed the experiments|performed infections|gathered the data|edited the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5584376	28870168	RL	PLoS52	designed the experiments|performed infections|gathered the data|edited the manuscript	performed infections	Performed the experiments	Investigation	YES
5584376	28870168	RL	PLoS52	designed the experiments|performed infections|gathered the data|edited the manuscript	gathered the data	Performed the experiments	Investigation	YES
5584376	28870168	RL	PLoS52	designed the experiments|performed infections|gathered the data|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5584376	28870168	SS	PLoS52	designed the experiments|gathered the data|edited the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5584376	28870168	SS	PLoS52	designed the experiments|gathered the data|edited the manuscript	gathered the data	Performed the experiments	Investigation	YES
5584376	28870168	SS	PLoS52	designed the experiments|gathered the data|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5584376	28870168	TE	PLoS52	designed the experiments|analyzed the data|drafted the manuscript|edited the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5584376	28870168	TE	PLoS52	designed the experiments|analyzed the data|drafted the manuscript|edited the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5584376	28870168	TE	PLoS52	designed the experiments|analyzed the data|drafted the manuscript|edited the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5584376	28870168	TE	PLoS52	designed the experiments|analyzed the data|drafted the manuscript|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5584376	28870168	all authors	PLoS52	contributed original ideas to the research and agreed on the final version of the manuscript	contributed original ideas to the research and agreed on the final version of the manuscript	Conceived and designed the experiments	Conceptualization	YES
5891438	29633046	AKS	2	performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
5891438	29633046	CT	2	studies and the interpretation of scans and drafted the manuscript|study design and the data evaluation, coordinated the project, and contributed to the manuscript	studies and the interpretation of scans and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5891438	29633046	CT	2	studies and the interpretation of scans and drafted the manuscript|study design and the data evaluation, coordinated the project, and contributed to the manuscript	study design and the data evaluation, coordinated the project, and contributed to the manuscript	Conceived and designed the experiments	Methodology|Project administration	YES
5891438	29633046	HG	2	was responsible for the selection and management of the patients included in the study	was responsible for the selection and management of the patients included in the study	Performed the experiments	Investigation|Project administration	YES
5891438	29633046	KK	2	was responsible for the radiotracers production	was responsible for the radiotracers production	-	-	NO
4414451	25923714	HBB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4414451	25923714	HBB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414451	25923714	XKM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414451	25923714	XKM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414451	25923714	XKM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414451	25923714	XKM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414451	25923714	YXZ	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4414451	25923714	YXZ	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414451	25923714	ZWL	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414451	25923714	ZWL	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3651299	23627832	AS	2	assisted with manuscript preparation	assisted with manuscript preparation	Wrote the paper	Writing - Original Draft	YES
3651299	23627832	CF	2	provided administrative oversight	provided administrative oversight	-	Supervision	YES
3651299	23627832	CW	2	was the primary investigator and designed the study|assisted with manuscript preparation	was the primary investigator and designed the study	Conceived and designed the experiments	Methodology	YES
3651299	23627832	CW	2	was the primary investigator and designed the study|assisted with manuscript preparation	assisted with manuscript preparation	Wrote the paper	Writing - Original Draft	YES
3651299	23627832	JO	2	was the primary author and prepared the manuscript	was the primary author and prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
3651299	23627832	LT	2	conducted all testing and statistical analysis	conducted all testing and statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3651299	23627832	RW	2	assisted with manuscript preparation	assisted with manuscript preparation	Wrote the paper	Writing - Original Draft	YES
3651299	23627832	SH	2	conducted all testing and statistical analysis	conducted all testing and statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3651299	23627832	SU	2	conducted all testing and statistical analysis	conducted all testing and statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3651299	23627832	SW	2	assisted with manuscript preparation	assisted with manuscript preparation	Wrote the paper	Writing - Original Draft	YES
1888723	17579707	AC	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1888723	17579707	AC	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1888723	17579707	JH	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1888723	17579707	JH	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1888723	17579707	JS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1888723	17579707	JS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1888723	17579707	MA	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1888723	17579707	MA	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1888723	17579707	MB	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1888723	17579707	MB	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1888723	17579707	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1888723	17579707	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1888723	17579707	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1888723	17579707	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1888723	17579707	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1888723	17579707	MN	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1888723	17579707	PO	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1888723	17579707	PS	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1888723	17579707	PS	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1888723	17579707	PZ	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1888723	17579707	PZ	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1888723	17579707	RS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1888723	17579707	RS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1888723	17579707	RS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1888723	17579707	SC	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1888723	17579707	SC	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1888723	17579707	SK	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1888723	17579707	UB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1888723	17579707	UB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1888723	17579707	UB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4766140	26910902	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4766140	26910902	FOP	2	were involved in performing the statistical analysis	were involved in performing the statistical analysis	Analyzed the data	Formal analysis	YES
4766140	26910902	GL	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
4766140	26910902	JF	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
4766140	26910902	JT	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
4766140	26910902	JW	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
4766140	26910902	KLP	2	carried out the experiments|carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
4766140	26910902	KLP	2	carried out the experiments|carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
4766140	26910902	LML	2	carried out the experiments|were involved in performing the statistical analysis|wrote the first draft	carried out the experiments	Performed the experiments	Investigation	YES
4766140	26910902	LML	2	carried out the experiments|were involved in performing the statistical analysis|wrote the first draft	were involved in performing the statistical analysis	Analyzed the data	Formal analysis	YES
4766140	26910902	LML	2	carried out the experiments|were involved in performing the statistical analysis|wrote the first draft	wrote the first draft	Wrote the paper	Writing - Original Draft	YES
4766140	26910902	MS	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
4766140	26910902	RM	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5584509	28874118	AC	PLoS52	conceived and designed the study|wrote the manuscript with contributions from all other authors	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5584509	28874118	AC	PLoS52	conceived and designed the study|wrote the manuscript with contributions from all other authors	wrote the manuscript with contributions from all other authors	Wrote the paper	Writing - Original Draft	YES
5584509	28874118	AP	PLoS52	analyzed and interpreted the data	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5584509	28874118	AS	PLoS52	analyzed and interpreted the data	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5584509	28874118	EB	PLoS52	analyzed and interpreted the data|wrote the manuscript with contributions from all other authors	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5584509	28874118	EB	PLoS52	analyzed and interpreted the data|wrote the manuscript with contributions from all other authors	wrote the manuscript with contributions from all other authors	Wrote the paper	Writing - Original Draft	YES
5584509	28874118	IA	PLoS52	analyzed and interpreted the data	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5584509	28874118	MB	PLoS52	conceived and designed the study|performed the experiments|wrote the manuscript with contributions from all other authors	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5584509	28874118	MB	PLoS52	conceived and designed the study|performed the experiments|wrote the manuscript with contributions from all other authors	performed the experiments	Performed the experiments	Investigation	YES
5584509	28874118	MB	PLoS52	conceived and designed the study|performed the experiments|wrote the manuscript with contributions from all other authors	wrote the manuscript with contributions from all other authors	Wrote the paper	Writing - Original Draft	YES
5584509	28874118	MG	PLoS52	performed the rna seq	performed the rna seq	Performed the experiments	Investigation	YES
5584509	28874118	MM	PLoS52	analyzed and interpreted the data|wrote the manuscript with contributions from all other authors	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5584509	28874118	MM	PLoS52	analyzed and interpreted the data|wrote the manuscript with contributions from all other authors	wrote the manuscript with contributions from all other authors	Wrote the paper	Writing - Original Draft	YES
5584509	28874118	MP	PLoS52	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5584509	28874118	PK	PLoS52	analyzed and interpreted the data	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
4606450	26495315	Hongbin Lin	2	contributed equally to this work	contributed equally to this work	-	-	NO
4606450	26495315	Yage Xing	2	contributed equally to this work	contributed equally to this work	-	-	NO
5895559	29644499	AR	2	participated in the design of the study and helped draft the manuscript	participated in the design of the study and helped draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5895559	29644499	CM	2	participated in the design of the study and helped draft the manuscript	participated in the design of the study and helped draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5895559	29644499	CP	2	concieved the study, participated in data collection and drafted the manuscript	concieved the study, participated in data collection and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5895559	29644499	ES	2	participated in the design of the study, helped draft the manuscript and coordinated the study	participated in the design of the study, helped draft the manuscript and coordinated the study	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft	YES
5895559	29644499	JS	2	participated in the design of the study and helped draft the manuscript	participated in the design of the study and helped draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5895559	29644499	KF	2	participated in data collection and analysis of results and helped draft the manuscript	participated in data collection and analysis of results and helped draft the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5895559	29644499	PW	2	participated in data collection	participated in data collection	Performed the experiments	Investigation	YES
5895559	29644499	RH	2	helped with statistical metholodogy and analysis of results	helped with statistical metholodogy and analysis of results	Analyzed the data	Formal analysis	YES
5714888	29250093	HY	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5714888	29250093	J-HZ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5714888	29250093	JF	PLoS52	supervised the study	supervised the study	-	Supervision	YES
5714888	29250093	JS	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5714888	29250093	L-LZ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5714888	29250093	RL	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5714888	29250093	SX	PLoS52	supervised the study|coordinated the overall study and edited the manuscript	supervised the study	-	Supervision	YES
5714888	29250093	SX	PLoS52	supervised the study|coordinated the overall study and edited the manuscript	coordinated the overall study and edited the manuscript	Wrote the paper	Project administration|Writing - Review & Editing	YES
5714888	29250093	W-MW	PLoS52	supervised the study|wrote the manuscript|coordinated the overall study and edited the manuscript	supervised the study	-	Supervision	YES
5714888	29250093	W-MW	PLoS52	supervised the study|wrote the manuscript|coordinated the overall study and edited the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5714888	29250093	W-MW	PLoS52	supervised the study|wrote the manuscript|coordinated the overall study and edited the manuscript	coordinated the overall study and edited the manuscript	Wrote the paper	Project administration|Writing - Review & Editing	YES
5714888	29250093	Y-JX	PLoS52	performed the experiments|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5714888	29250093	Y-JX	PLoS52	performed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5714888	29250093	YL	PLoS52	performed the experiments|supervised the study	performed the experiments	Performed the experiments	Investigation	YES
5714888	29250093	YL	PLoS52	performed the experiments|supervised the study	supervised the study	-	Supervision	YES
5714888	29250093	Z-XZ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
4414452	25923671	AF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414452	25923671	AF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414452	25923671	AF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414452	25923671	AF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414452	25923671	CB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414452	25923671	CB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414452	25923671	CB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414452	25923671	CB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414452	25923671	IRB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4414452	25923671	MM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4414452	25923671	OH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414452	25923671	OH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414452	25923671	OH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1888724	17579708	DL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1888724	17579708	DX	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1888724	17579708	DX	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1888724	17579708	HK	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1888724	17579708	LF	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1888724	17579708	PC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1888724	17579708	SZ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1888724	17579708	WL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1888724	17579708	XS	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1888724	17579708	XT	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1888724	17579708	YW	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1888724	17579708	YW	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1888724	17579708	YW	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3835483	24302856	E. Yamamoto	2	have contributed equally to this work	have contributed equally to this work	-	-	NO
3835483	24302856	F. Giangreco	2	have contributed equally to this work	have contributed equally to this work	-	-	NO
3835483	24302856	M. Hodoscek	2	have contributed equally to this work	have contributed equally to this work	-	-	NO
3835483	24302856	S. Hofinger	2	have contributed equally to this work	have contributed equally to this work	-	-	NO
3835483	24302856	V. Knecht	2	have contributed equally to this work	have contributed equally to this work	-	-	NO
3835483	24302856	Y. Hirano	2	have contributed equally to this work	have contributed equally to this work	-	-	NO
3661336	23627788	DA	2	carried out the study and collected the data	carried out the study and collected the data	Performed the experiments	Investigation	YES
3661336	23627788	MS	2	made all the statistical calculations	made all the statistical calculations	Analyzed the data	Formal analysis	YES
3661336	23627788	SS	2	participated in the sequence alignment and drafted the manuscript	participated in the sequence alignment and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5584555	28874136	A.D.	2	supervised the analysis, edited and approved the manuscript	supervised the analysis, edited and approved the manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
5584555	28874136	C.D.J.	2	supervised the analysis, edited and approved the manuscript	supervised the analysis, edited and approved the manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
5584555	28874136	J.A.	2	developed the software, generated the simulated data-set, obtained the results, analyzed them and prepared the manuscript	developed the software, generated the simulated data-set, obtained the results, analyzed them and prepared the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Software|Writing - Original Draft	YES
5584555	28874136	N.G.	2	participated in method development and adapting the practical applications|supervised the analysis, edited and approved the manuscript	participated in method development and adapting the practical applications	Performed the experiments	Methodology	YES
5584555	28874136	N.G.	2	participated in method development and adapting the practical applications|supervised the analysis, edited and approved the manuscript	supervised the analysis, edited and approved the manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
4606451	26495306	Akira Hyoda	2	made the study design, conducted the study and data analysis, and wrote the paper	made the study design, conducted the study and data analysis, and wrote the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4606451	26495306	All authors	2	discussed the results and approved the final paper	discussed the results and approved the final paper	-	-	NO
4606451	26495306	Nobuyasu Komasawa	2	made the study design, conducted the study and data analysis, and wrote the paper	made the study design, conducted the study and data analysis, and wrote the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4606451	26495306	Nozomi Majima	2	conducted the study and data analysis	conducted the study and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4606451	26495306	Sayuri Matsunami	2	conducted the study and data analysis	conducted the study and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4606451	26495306	Toshiaki Minami	2	was responsible for the study design and paper preparation	was responsible for the study design and paper preparation	Conceived and designed the experiments	Methodology	YES
4773312	26931430	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4773312	26931430	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4773312	26931430	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4773312	26931430	DNO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4773312	26931430	DNO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4773312	26931430	DNO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4773312	26931430	GFCR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4773312	26931430	GFCR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4773312	26931430	GFCR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4773312	26931430	GFCR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4773312	26931430	JBC	PLoS5	Analyzed the data|Contributed reagents/ materials/ financing support/ analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4773312	26931430	JBC	PLoS5	Analyzed the data|Contributed reagents/ materials/ financing support/ analysis tools|Wrote the paper	Contributed reagents/ materials/ financing support/ analysis tools	Contributed reagents/materials/analysis tools	Funding acquisition|Resources	YES
4773312	26931430	JBC	PLoS5	Analyzed the data|Contributed reagents/ materials/ financing support/ analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4773312	26931430	LCGO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4773312	26931430	LCGO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4773312	26931430	LCGO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4773312	26931430	LJ	PLoS5	Analyzed the data|Contributed reagents/ materials/ financing support/ analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4773312	26931430	LJ	PLoS5	Analyzed the data|Contributed reagents/ materials/ financing support/ analysis tools	Contributed reagents/ materials/ financing support/ analysis tools	Contributed reagents/materials/analysis tools	Funding acquisition|Resources	YES
4773312	26931430	LVZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4773312	26931430	LVZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4773312	26931430	LVZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4773312	26931430	MAVS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4773312	26931430	MAVS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4773312	26931430	MAVS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4773312	26931430	MRZP	PLoS5	Contributed reagents/ materials/ financing support/ analysis tools	Contributed reagents/ materials/ financing support/ analysis tools	Contributed reagents/materials/analysis tools	Funding acquisition|Resources	YES
4773312	26931430	PLR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/ materials/ financing support/ analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4773312	26931430	PLR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/ materials/ financing support/ analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4773312	26931430	PLR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/ materials/ financing support/ analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4773312	26931430	PLR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/ materials/ financing support/ analysis tools|Wrote the paper	Contributed reagents/ materials/ financing support/ analysis tools	Contributed reagents/materials/analysis tools	Funding acquisition|Resources	YES
4773312	26931430	PLR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/ materials/ financing support/ analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4773312	26931430	RCSR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/ materials/ financing support/ analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4773312	26931430	RCSR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/ materials/ financing support/ analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4773312	26931430	RCSR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/ materials/ financing support/ analysis tools	Contributed reagents/ materials/ financing support/ analysis tools	Contributed reagents/materials/analysis tools	Funding acquisition|Resources	YES
4773312	26931430	SPV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/ materials/ financing support/ analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4773312	26931430	SPV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/ materials/ financing support/ analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4773312	26931430	SPV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/ materials/ financing support/ analysis tools|Wrote the paper	Contributed reagents/ materials/ financing support/ analysis tools	Contributed reagents/materials/analysis tools	Funding acquisition|Resources	YES
4773312	26931430	SPV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/ materials/ financing support/ analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3661339	23680457	AHLJ	2	were significant manuscript revisers/reviewers|participated in the concept and design	were significant manuscript revisers/reviewers	Wrote the paper	Writing - Review & Editing	YES
3661339	23680457	AHLJ	2	were significant manuscript revisers/reviewers|participated in the concept and design	participated in the concept and design	Conceived and designed the experiments	Conceptualization	YES
3661339	23680457	BG	2	were significant manuscript writers|participated in the concept and design|participated in data analysis and interpretation	were significant manuscript writers	Wrote the paper	Writing - Original Draft	YES
3661339	23680457	BG	2	were significant manuscript writers|participated in the concept and design|participated in data analysis and interpretation	participated in the concept and design	Conceived and designed the experiments	Conceptualization	YES
3661339	23680457	BG	2	were significant manuscript writers|participated in the concept and design|participated in data analysis and interpretation	participated in data analysis and interpretation	Analyzed the data	Formal analysis	YES
3661339	23680457	HR	2	were significant manuscript revisers/reviewers|participated in the concept and design|participated in data analysis and interpretation	were significant manuscript revisers/reviewers	Wrote the paper	Writing - Review & Editing	YES
3661339	23680457	HR	2	were significant manuscript revisers/reviewers|participated in the concept and design|participated in data analysis and interpretation	participated in the concept and design	Conceived and designed the experiments	Conceptualization	YES
3661339	23680457	HR	2	were significant manuscript revisers/reviewers|participated in the concept and design|participated in data analysis and interpretation	participated in data analysis and interpretation	Analyzed the data	Formal analysis	YES
3661339	23680457	ML	2	were significant manuscript revisers/reviewers|were responsible for data acquisition	were significant manuscript revisers/reviewers	Wrote the paper	Writing - Review & Editing	YES
3661339	23680457	ML	2	were significant manuscript revisers/reviewers|were responsible for data acquisition	were responsible for data acquisition	Performed the experiments	Investigation	YES
3661339	23680457	MTS	2	were significant manuscript revisers/reviewers|were responsible for data acquisition	were significant manuscript revisers/reviewers	Wrote the paper	Writing - Review & Editing	YES
3661339	23680457	MTS	2	were significant manuscript revisers/reviewers|were responsible for data acquisition	were responsible for data acquisition	Performed the experiments	Investigation	YES
3661339	23680457	RL	2	were significant manuscript writers|were responsible for data acquisition|participated in data analysis and interpretation	were significant manuscript writers	Wrote the paper	Writing - Original Draft	YES
3661339	23680457	RL	2	were significant manuscript writers|were responsible for data acquisition|participated in data analysis and interpretation	were responsible for data acquisition	Performed the experiments	Investigation	YES
3661339	23680457	RL	2	were significant manuscript writers|were responsible for data acquisition|participated in data analysis and interpretation	participated in data analysis and interpretation	Analyzed the data	Formal analysis	YES
3661339	23680457	VSP	2	were responsible for data acquisition|participated in data analysis and interpretation	were responsible for data acquisition	Performed the experiments	Investigation	YES
3661339	23680457	VSP	2	were responsible for data acquisition|participated in data analysis and interpretation	participated in data analysis and interpretation	Analyzed the data	Formal analysis	YES
5897267	29651565	ASch	2	was involved in the in vitro and in vivo evaluation, performed the data evaluation and interpretation, and revised the manuscript	was involved in the in vitro and in vivo evaluation, performed the data evaluation and interpretation, and revised the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
5897267	29651565	HJW	2	initiated the development and evaluation of the eue-based inhibitors, participated in the data interpretation and in writing the manuscript and revising the final manuscript	initiated the development and evaluation of the eue-based inhibitors, participated in the data interpretation and in writing the manuscript and revising the final manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5897267	29651565	MR	2	imaging of the patients as well as image and data interpretation, drafted the human studies, and revised the final manuscript	imaging of the patients as well as image and data interpretation, drafted the human studies, and revised the final manuscript	Analyzed the data|Wrote the paper	Formal analysis|Visualization|Writing - Original Draft|Writing - Review & Editing	YES
5897267	29651565	PSMA	2	inhibitors and participated in the data interpretation and in revising the manuscript|inhibitors and participated in the data interpretation and in revising the final manuscript	inhibitors and participated in the data interpretation and in revising the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5897267	29651565	PSMA	2	inhibitors and participated in the data interpretation and in revising the manuscript|inhibitors and participated in the data interpretation and in revising the final manuscript	inhibitors and participated in the data interpretation and in revising the final manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4414453	25923916	AP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4414453	25923916	AP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414453	25923916	BB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414453	25923916	BB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414453	25923916	BB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414453	25923916	BB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414453	25923916	CT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414453	25923916	CT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414453	25923916	CT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414453	25923916	CT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414453	25923916	EKS	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414453	25923916	EKS	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4414453	25923916	EST	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4414453	25923916	EST	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414453	25923916	JB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4414453	25923916	JB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414453	25923916	MJB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4414453	25923916	MJB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414453	25923916	MKS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414453	25923916	MKS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414453	25923916	MKS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414453	25923916	STN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414453	25923916	STN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414453	25923916	STN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414453	25923916	STN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414453	25923916	YWL	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5714895	29250090	GP	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5714895	29250090	MASM	PLoS52	designed the experiment|wrote the paper	designed the experiment	Conceived and designed the experiments	Methodology	YES
5714895	29250090	MASM	PLoS52	designed the experiment|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5714895	29250090	NR	PLoS52	designed the experiment|performed the sequencing experiments|analyzed the data|wrote the paper	designed the experiment	Conceived and designed the experiments	Methodology	YES
5714895	29250090	NR	PLoS52	designed the experiment|performed the sequencing experiments|analyzed the data|wrote the paper	performed the sequencing experiments	Performed the experiments	Investigation	YES
5714895	29250090	NR	PLoS52	designed the experiment|performed the sequencing experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5714895	29250090	NR	PLoS52	designed the experiment|performed the sequencing experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5714895	29250090	SL	PLoS52	analyzed the data|developed the machine-learning pipeline|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5714895	29250090	SL	PLoS52	analyzed the data|developed the machine-learning pipeline|wrote the paper	developed the machine-learning pipeline	Analyzed the data	Formal analysis	YES
5714895	29250090	SL	PLoS52	analyzed the data|developed the machine-learning pipeline|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5714895	29250090	VR	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
1888725	17579709	AH	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1888725	17579709	AH	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1888725	17579709	GH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1888725	17579709	GH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1888725	17579709	LV	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1888725	17579709	LV	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1888725	17579709	LV	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1888725	17579709	MA	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1888725	17579709	MA	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1888725	17579709	PB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1888725	17579709	PB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1888725	17579709	PB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1888725	17579709	TT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1888725	17579709	TT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1888725	17579709	TT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1888725	17579709	TT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1888725	17579709	TT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5585901	28877668	DN	2	histology interpretation	histology interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3669033	23705671	AG	2	participated in the study design and coordination of subject visits	participated in the study design and coordination of subject visits	Conceived and designed the experiments	Methodology|Project administration	YES
3669033	23705671	Each author	2	contributed significantly to the successful carriage of this study	contributed significantly to the successful carriage of this study	-	-	NO
3669033	23705671	JT	2	coordinated the irb approval, subject visits, and sample inventory	coordinated the irb approval, subject visits, and sample inventory	-	Project administration	YES
3669033	23705671	MP	2	participated in the study design and coordination of subject visits	participated in the study design and coordination of subject visits	Conceived and designed the experiments	Methodology|Project administration	YES
3669033	23705671	ST	2	designed the study and drafted the manuscript	designed the study and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4775715	26936848	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4775715	26936848	CG	2	carried out the hplc analysis	carried out the hplc analysis	Performed the experiments	Investigation	YES
4775715	26936848	EA	2	pretreatment experiments	pretreatment experiments	-	-	NO
4775715	26936848	OP	2	contributed to analyze all the results and to draft the manuscript	contributed to analyze all the results and to draft the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4775715	26936848	SG	2	carried out the hydrolysis experiments and analyzed all the results	carried out the hydrolysis experiments and analyzed all the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4775715	26936848	SM	2	wrote the main manuscript text and prepared figures and tables|carried out the hydrolysis experiments and analyzed all the results	wrote the main manuscript text and prepared figures and tables	Wrote the paper	Visualization|Writing - Original Draft	YES
4775715	26936848	SM	2	wrote the main manuscript text and prepared figures and tables|carried out the hydrolysis experiments and analyzed all the results	carried out the hydrolysis experiments and analyzed all the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4775715	26936848	VB	2	designed the hydrolysis experiments and contributed to analyze the results	designed the hydrolysis experiments and contributed to analyze the results	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
4775715	26936848	VF	2	contributed to conceiving the study and participated in its design and coordination and drafted the manuscript|is the corresponding author	contributed to conceiving the study and participated in its design and coordination and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
4775715	26936848	VF	2	contributed to conceiving the study and participated in its design and coordination and drafted the manuscript|is the corresponding author	is the corresponding author	-	-	NO
3671129	23705637	David de Oliveira	2	participated in the collection of data, biochemical evaluation and statistical analysis	participated in the collection of data, biochemical evaluation and statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3671129	23705637	Grace Dourado	2	participated in the collection of data, biochemical evaluation and statistical analysis	participated in the collection of data, biochemical evaluation and statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3671129	23705637	Thais Cesar	2	who was the mentor of this work	who was the mentor of this work	-	-	NO
3671129	23705637	The authors	2	participated in the collection of data, biochemical evaluation and statistical analysis	participated in the collection of data, biochemical evaluation and statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4414455	25923807	HZ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414455	25923807	LC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414455	25923807	LC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414455	25923807	LC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414455	25923807	LC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414455	25923807	LC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414455	25923807	QJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414455	25923807	QJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414455	25923807	QJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414455	25923807	QJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414455	25923807	XC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4414455	25923807	XC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414455	25923807	YW	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414455	25923807	YX	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414455	25923807	YX	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414455	25923807	YX	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414455	25923807	ZX	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414455	25923807	ZX	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414455	25923807	ZX	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5714927	29250096	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5714927	29250096	IS	2	supervised the rote the manuscript under a	supervised the rote the manuscript under a	-	Supervision	YES
5714927	29250096	MK	2	supervised the arried out all the experiments and data analyses under a|supervised the rote the manuscript under a	supervised the arried out all the experiments and data analyses under a	Analyzed the data	Formal analysis|Supervision	YES
5714927	29250096	MK	2	supervised the arried out all the experiments and data analyses under a|supervised the rote the manuscript under a	supervised the rote the manuscript under a	-	Supervision	YES
5897268	29651571	CG	2	contributed to the data collection, data analysis, and writing of the manuscript	contributed to the data collection, data analysis, and writing of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5897268	29651571	DE	2	contributed to the neuropsychological testing and interpretation	contributed to the neuropsychological testing and interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5897268	29651571	JVDS	2	contributed to the neuropsychological testing and interpretation	contributed to the neuropsychological testing and interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5897268	29651571	KEG	2	contributed to the study design, interpretation of data, and revision of the manuscript	contributed to the study design, interpretation of data, and revision of the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Review & Editing	YES
5897268	29651571	KVB	2	contributed to the neuropsychological testing and interpretation	contributed to the neuropsychological testing and interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5897268	29651571	LS	2	contributed to the study design, interpretation of data, and revision of the manuscript	contributed to the study design, interpretation of data, and revision of the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Review & Editing	YES
5897268	29651571	PD	2	contributed to the study design, interpretation of data, and revision of the manuscript	contributed to the study design, interpretation of data, and revision of the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Review & Editing	YES
5897268	29651571	PK	2	contributed to the neuropsychological testing and interpretation	contributed to the neuropsychological testing and interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5897268	29651571	TT	2	contributed to the neurosurgery	contributed to the neurosurgery	Performed the experiments	Investigation	YES
5897268	29651571	VLJ	2	contributed to the neurosurgery	contributed to the neurosurgery	Performed the experiments	Investigation	YES
5897268	29651571	WVP	2	contributed to the study design, interpretation of data, and revision of the manuscript	contributed to the study design, interpretation of data, and revision of the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Review & Editing	YES
1888726	17579710	AB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1888726	17579710	AB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1888726	17579710	AB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1888726	17579710	AB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1888726	17579710	AH	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1888726	17579710	AH	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1888726	17579710	BG	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1888726	17579710	BG	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1888726	17579710	BG	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1888726	17579710	BG	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1888726	17579710	BS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1888726	17579710	BS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1888726	17579710	CM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1888726	17579710	CM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1888726	17579710	CM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1888726	17579710	DH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1888726	17579710	DH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1888726	17579710	DH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1888726	17579710	FJ	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1888726	17579710	FJ	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1888726	17579710	IV	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1888726	17579710	IV	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1888726	17579710	KL	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1888726	17579710	KL	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1888726	17579710	KM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1888726	17579710	KM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1888726	17579710	KM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1888726	17579710	PA	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1888726	17579710	PA	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1888726	17579710	PA	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1888726	17579710	QL	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1888726	17579710	QL	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1888726	17579710	RC	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1888726	17579710	RC	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1888726	17579710	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1888726	17579710	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1888726	17579710	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1888726	17579710	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1888726	17579710	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1888726	17579710	TG	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1888726	17579710	TG	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1888726	17579710	TG	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4775720	26936849	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4775720	26936849	MI	2	conceived of this study and wrote the manuscript	conceived of this study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4775720	26936849	The authors	2	have declared that they have no competing interests	have declared that they have no competing interests	-	-	NO
4775720	26936849	YI	2	conceived of this study and wrote the manuscript|carried out the experiment	conceived of this study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4775720	26936849	YI	2	conceived of this study and wrote the manuscript|carried out the experiment	carried out the experiment	Performed the experiments	Investigation	YES
3674971	23724789	AM	2	conceived of the study, and participated in its design and coordination and helped to draft the manuscript	conceived of the study, and participated in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
3674971	23724789	JS	2	were the principle investigators of the study|conceived of the study, and participated in its design and coordination and helped to draft the manuscript	were the principle investigators of the study	-	-	NO
3674971	23724789	JS	2	were the principle investigators of the study|conceived of the study, and participated in its design and coordination and helped to draft the manuscript	conceived of the study, and participated in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
3674971	23724789	MT	2	aided with data collection and analysis	aided with data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3674971	23724789	NM	2	conceived of the study, and participated in its design and coordination and helped to draft the manuscript|provided the supplements and proposed the idea of the study	conceived of the study, and participated in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
3674971	23724789	NM	2	conceived of the study, and participated in its design and coordination and helped to draft the manuscript|provided the supplements and proposed the idea of the study	provided the supplements and proposed the idea of the study	Conceived and designed the experiments	Conceptualization	YES
3674971	23724789	RP	2	were the principle investigators of the study	were the principle investigators of the study	-	-	NO
5585943	28874114	CD	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
5585943	28874114	CD	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5585943	28874114	CFU	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5585943	28874114	CFU	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5585943	28874114	CFU	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5585943	28874114	CG	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
5585943	28874114	CG	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5585943	28874114	DE	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
5585943	28874114	DE	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5585943	28874114	IGM	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5585943	28874114	JPL	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
5585943	28874114	JPL	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5585943	28874114	KS	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5585943	28874114	MJN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5585943	28874114	MJN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
5585943	28874114	MJN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5585943	28874114	MJN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5585943	28874114	MS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
5585943	28874114	MS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5585943	28874114	PS	PLoS5	Contributed material/reagents	Contributed material/reagents	Contributed reagents/materials/analysis tools	Resources	YES
5715234	29250088	DW	7	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5715234	29250088	HL	7	analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5715234	29250088	HL	7	analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5715234	29250088	LQ	7	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5715234	29250088	RG	7	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5715234	29250088	SW	7	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5715234	29250088	XF	7	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5715234	29250088	YG	7	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5715234	29250088	YL	7	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5715234	29250088	ZL	7	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5715234	29250088	ZL	7	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5715234	29250088	ZL	7	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5715234	29250088	ZL	7	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5715234	29250088	ZW	7	performed the experiments|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5715234	29250088	ZW	7	performed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5897276	29651569	BK	2	contributed to the analysis and interpretation of the data	contributed to the analysis and interpretation of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5897276	29651569	JK	2	designed the study, performed the data analysis, and wrote the manuscript	designed the study, performed the data analysis, and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5897276	29651569	KR	2	designed the study, performed the data analysis, and wrote the manuscript	designed the study, performed the data analysis, and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5897276	29651569	LS	2	contributed to the preparation of the study and the interpretation of the data	contributed to the preparation of the study and the interpretation of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5897276	29651569	MS	2	contributed to the analysis and interpretation of the data	contributed to the analysis and interpretation of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5897276	29651569	SS	2	contributed to the preparation of the study and the interpretation of the data	contributed to the preparation of the study and the interpretation of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
4414456	25923960	CL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Modified manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414456	25923960	CL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Modified manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4414456	25923960	CL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Modified manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4414456	25923960	CL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Modified manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414456	25923960	CL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Modified manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414456	25923960	CL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Modified manuscript	Modified manuscript	Wrote the paper	Writing - Review & Editing	YES
4414456	25923960	CMC	PLoS5	Critical review and comments|Modified manuscript	Critical review and comments	-	-	NO
4414456	25923960	CMC	PLoS5	Critical review and comments|Modified manuscript	Modified manuscript	Wrote the paper	Writing - Review & Editing	YES
4414456	25923960	HYY	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414456	25923960	HYY	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414456	25923960	HYY	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414456	25923960	JL	PLoS5	Critical review and comments|Modified manuscript	Critical review and comments	-	-	NO
4414456	25923960	JL	PLoS5	Critical review and comments|Modified manuscript	Modified manuscript	Wrote the paper	Writing - Review & Editing	YES
4414456	25923960	SLS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Modified manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414456	25923960	SLS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Modified manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414456	25923960	SLS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Modified manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414456	25923960	SLS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Modified manuscript	Modified manuscript	Wrote the paper	Writing - Review & Editing	YES
3680189	23731903	Both authors	2	were involved with the writing, editing and approval of the final manuscript	were involved with the writing, editing and approval of the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3680189	23731903	KB	2	was responsible for the concept of this project|were responsible for the study design, acquisition of data, analysis and interpretation of the data	was responsible for the concept of this project	Conceived and designed the experiments	Conceptualization	YES
3680189	23731903	KB	2	was responsible for the concept of this project|were responsible for the study design, acquisition of data, analysis and interpretation of the data	were responsible for the study design, acquisition of data, analysis and interpretation of the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
3680189	23731903	SC	2	were responsible for the study design, acquisition of data, analysis and interpretation of the data	were responsible for the study design, acquisition of data, analysis and interpretation of the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
4788993	26970766	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4788993	26970766	DLP	2	conceived the investigation	conceived the investigation	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
4788993	26970766	MCM	2	performed experiments and data analysis comparing manual and automated assays	performed experiments and data analysis comparing manual and automated assays	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4788993	26970766	MDP	2	characterized automated liquid handler performance	characterized automated liquid handler performance	Performed the experiments	Investigation	YES
4788993	26970766	NIST	2	program provided support for mcm	program provided support for mcm	-	-	NO
4788993	26970766	NJL	2	conceived the investigation	conceived the investigation	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
4788993	26970766	SPF	2	performed experiments and data analysis comparing manual and automated assays|conceived the investigation|drafted this report	performed experiments and data analysis comparing manual and automated assays	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4788993	26970766	SPF	2	performed experiments and data analysis comparing manual and automated assays|conceived the investigation|drafted this report	conceived the investigation	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
4788993	26970766	SPF	2	performed experiments and data analysis comparing manual and automated assays|conceived the investigation|drafted this report	drafted this report	Wrote the paper	Writing - Original Draft	YES
4788993	26970766	SURF	2	program provided support for mcm	program provided support for mcm	-	-	NO
4788993	26970766	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
1888727	17565378	DA	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1888727	17565378	JS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1888727	17565378	KP	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1888727	17565378	KP	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1888727	17565378	ML	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1888727	17565378	ML	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1888727	17565378	ML	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1888727	17565378	MW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1888727	17565378	MW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1888727	17565378	MW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1888727	17565378	RH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1888727	17565378	RH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1888727	17565378	RH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1888727	17565378	SB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1888727	17565378	SB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1888727	17565378	SB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1888727	17565378	SS	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1888727	17565378	SS	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1888727	17565378	VB	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4414459	25922935	GP	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414459	25922935	GT	PLoS5	Wrote the paper|Obtained requisite permits for animal ethics and research consent	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414459	25922935	GT	PLoS5	Wrote the paper|Obtained requisite permits for animal ethics and research consent	Obtained requisite permits for animal ethics and research consent	-	Project administration	YES
4414459	25922935	JZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Obtained requisite permits for animal ethics and research consent	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414459	25922935	JZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Obtained requisite permits for animal ethics and research consent	Performed the experiments	Performed the experiments	Investigation	YES
4414459	25922935	JZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Obtained requisite permits for animal ethics and research consent	Analyzed the data	Analyzed the data	Formal analysis	YES
4414459	25922935	JZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Obtained requisite permits for animal ethics and research consent	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414459	25922935	JZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Obtained requisite permits for animal ethics and research consent	Obtained requisite permits for animal ethics and research consent	-	Project administration	YES
4414459	25922935	KO	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Obtained requisite permits for animal ethics and research consent	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414459	25922935	KO	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Obtained requisite permits for animal ethics and research consent	Performed the experiments	Performed the experiments	Investigation	YES
4414459	25922935	KO	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Obtained requisite permits for animal ethics and research consent	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414459	25922935	KO	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Obtained requisite permits for animal ethics and research consent	Obtained requisite permits for animal ethics and research consent	-	Project administration	YES
4414459	25922935	TD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Obtained requisite permits for animal ethics and research consent	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414459	25922935	TD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Obtained requisite permits for animal ethics and research consent	Performed the experiments	Performed the experiments	Investigation	YES
4414459	25922935	TD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Obtained requisite permits for animal ethics and research consent	Analyzed the data	Analyzed the data	Formal analysis	YES
4414459	25922935	TD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Obtained requisite permits for animal ethics and research consent	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414459	25922935	TD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Obtained requisite permits for animal ethics and research consent	Obtained requisite permits for animal ethics and research consent	-	Project administration	YES
5715236	29250091	All authors	2	have contributed to, approved the manuscript	have contributed to, approved the manuscript	-	-	NO
5585954	28874137	BY	PLoS52	conceived the experiments|coordinated the manuscript writing	conceived the experiments	Conceived and designed the experiments	Conceptualization	YES
5585954	28874137	BY	PLoS52	conceived the experiments|coordinated the manuscript writing	coordinated the manuscript writing	Wrote the paper	Project administration|Writing - Original Draft	YES
5585954	28874137	CD	PLoS52	conceived the experiments|performed experiments|analyzed the data|collected samples and wrote the paper	conceived the experiments	Conceived and designed the experiments	Conceptualization	YES
5585954	28874137	CD	PLoS52	conceived the experiments|performed experiments|analyzed the data|collected samples and wrote the paper	performed experiments	Performed the experiments	Investigation	YES
5585954	28874137	CD	PLoS52	conceived the experiments|performed experiments|analyzed the data|collected samples and wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5585954	28874137	CD	PLoS52	conceived the experiments|performed experiments|analyzed the data|collected samples and wrote the paper	collected samples and wrote the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5585954	28874137	CZ	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5585954	28874137	JM	PLoS52	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5585954	28874137	LZ	PLoS52	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5585954	28874137	TL	PLoS52	collected samples and wrote the paper	collected samples and wrote the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5585954	28874137	XZ	PLoS52	conceived the experiments|coordinated the manuscript writing	conceived the experiments	Conceived and designed the experiments	Conceptualization	YES
5585954	28874137	XZ	PLoS52	conceived the experiments|coordinated the manuscript writing	coordinated the manuscript writing	Wrote the paper	Project administration|Writing - Original Draft	YES
5902437	29663167	AW	2	carried out a part of the molecular modeling	carried out a part of the molecular modeling	Performed the experiments	Investigation|Methodology	YES
5902437	29663167	JCzD	2	consulted the molecular modeling and revised the manuscript	consulted the molecular modeling and revised the manuscript	Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
5902437	29663167	MKD	2	interpreted the nmr data	interpreted the nmr data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5902437	29663167	MM	2	performed the in vitro studies and radiolabeling	performed the in vitro studies and radiolabeling	Performed the experiments	Investigation	YES
5902437	29663167	MO	2	conducted the in vitro studies, especially the binding assays	conducted the in vitro studies, especially the binding assays	Performed the experiments	Investigation	YES
5902437	29663167	NMN	2	performed the nmr measurements	performed the nmr measurements	Performed the experiments	Investigation	YES
5902437	29663167	PFJL	2	carried out the molecular modeling and wrote the manuscript	carried out the molecular modeling and wrote the manuscript	Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5902437	29663167	PG	2	designed the study, managed the project, and revised the manuscript	designed the study, managed the project, and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Review & Editing	YES
5902437	29663167	RM	2	designed the study, managed the project, and revised the manuscript	designed the study, managed the project, and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Review & Editing	YES
5902437	29663167	RS	2	performed the nmr measurements	performed the nmr measurements	Performed the experiments	Investigation	YES
4792827	26980601	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4792827	26980601	MAH	2	contributed in data interpretation, coordination and manuscript revision	contributed in data interpretation, coordination and manuscript revision	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Project administration|Resources|Writing - Review & Editing	YES
4792827	26980601	MS	2	carried out the coordination of the research work with concept development and helped in manuscript draft preparation and critical revision of the draft	carried out the coordination of the research work with concept development and helped in manuscript draft preparation and critical revision of the draft	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Project administration|Writing - Original Draft|Writing - Review & Editing	YES
4792827	26980601	RPC	2	were involved in molecular cloning analysis of aioa gene	were involved in molecular cloning analysis of aioa gene	Performed the experiments	Investigation	YES
4792827	26980601	SH	2	participated in geo-chemical parameter analysis of soil samples	participated in geo-chemical parameter analysis of soil samples	Performed the experiments	Investigation	YES
4792827	26980601	SKS	2	carried out sampling, microbiological, molecular analysis and data interpretation|were involved in molecular cloning analysis of aioa gene	carried out sampling, microbiological, molecular analysis and data interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4792827	26980601	SKS	2	carried out sampling, microbiological, molecular analysis and data interpretation|were involved in molecular cloning analysis of aioa gene	were involved in molecular cloning analysis of aioa gene	Performed the experiments	Investigation	YES
4792827	26980601	TJM	2	carried out sampling, microbiological, molecular analysis and data interpretation|participated in geo-chemical parameter analysis of soil samples	carried out sampling, microbiological, molecular analysis and data interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4792827	26980601	TJM	2	carried out sampling, microbiological, molecular analysis and data interpretation|participated in geo-chemical parameter analysis of soil samples	participated in geo-chemical parameter analysis of soil samples	Performed the experiments	Investigation	YES
4792827	26980601	UGC	2	of bangladesh	of bangladesh	-	-	NO
1888728	17579711	EV	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1888728	17579711	EV	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1888728	17579711	EV	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1888728	17579711	JS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1888728	17579711	JS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1888728	17579711	JS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1888728	17579711	JS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1888728	17579711	LJ	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1888728	17579711	LJ	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1888728	17579711	LJ	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1888728	17579711	MB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1888728	17579711	MB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1888728	17579711	MB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1888728	17579711	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1888728	17579711	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1888728	17579711	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1888728	17579711	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1888728	17579711	MW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1888728	17579711	MW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1888728	17579711	MW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1888728	17579711	MW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1888728	17579711	MW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1888728	17579711	SL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1888728	17579711	SL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1888728	17579711	SL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1888728	17579711	TH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1888728	17579711	TH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1888728	17579711	TH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3685561	23758838	SL	2	conceived the study design	conceived the study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5715272	29250085	AP	2	helped in the experimental design, contributed to experimental procedures and reviewed the manuscript	helped in the experimental design, contributed to experimental procedures and reviewed the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
5715272	29250085	AdS	2	equally designed and contributed to the experimental procedures and writing of the manuscript	equally designed and contributed to the experimental procedures and writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5715272	29250085	CS	2	helped in the experimental design, contributed to experimental procedures and reviewed the manuscript	helped in the experimental design, contributed to experimental procedures and reviewed the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
5715272	29250085	FF	2	helped in the experimental design, contributed to experimental procedures and reviewed the manuscript	helped in the experimental design, contributed to experimental procedures and reviewed the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
5715272	29250085	HA	2	helped in the experimental design, contributed to experimental procedures and reviewed the manuscript	helped in the experimental design, contributed to experimental procedures and reviewed the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
5715272	29250085	HAE	2	equally designed and contributed to the experimental procedures and writing of the manuscript	equally designed and contributed to the experimental procedures and writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5715272	29250085	JT	2	helped in the experimental design, contributed to experimental procedures and reviewed the manuscript	helped in the experimental design, contributed to experimental procedures and reviewed the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
5715272	29250085	MA	2	helped in the experimental design, contributed to experimental procedures and reviewed the manuscript	helped in the experimental design, contributed to experimental procedures and reviewed the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
5715272	29250085	SAJ	2	helped in the experimental design, contributed to experimental procedures and reviewed the manuscript	helped in the experimental design, contributed to experimental procedures and reviewed the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
5715272	29250085	SB-N	2	helped in the experimental design, contributed to experimental procedures and reviewed the manuscript	helped in the experimental design, contributed to experimental procedures and reviewed the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
5715272	29250085	SS	2	helped in the experimental design, contributed to experimental procedures and reviewed the manuscript	helped in the experimental design, contributed to experimental procedures and reviewed the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
5715272	29250085	TB	2	helped in the experimental design, contributed to experimental procedures and reviewed the manuscript	helped in the experimental design, contributed to experimental procedures and reviewed the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
5585965	28874116	CD	2	oversaw the study and aided with interpretation and conclusions	oversaw the study and aided with interpretation and conclusions	Analyzed the data	Formal analysis|Supervision	YES
5585965	28874116	DD	2	generated rna libraries for sequencing	generated rna libraries for sequencing	Performed the experiments	Investigation	YES
5585965	28874116	DKM	2	performed histological analysis	performed histological analysis	Performed the experiments	Investigation	YES
5585965	28874116	KDK	2	generated rna libraries for sequencing|conducted data analysis and interpretation|wrote the paper, and all authors provided feedback and have approved the final manuscript	generated rna libraries for sequencing	Performed the experiments	Investigation	YES
5585965	28874116	KDK	2	generated rna libraries for sequencing|conducted data analysis and interpretation|wrote the paper, and all authors provided feedback and have approved the final manuscript	conducted data analysis and interpretation	Analyzed the data	Formal analysis	YES
5585965	28874116	KDK	2	generated rna libraries for sequencing|conducted data analysis and interpretation|wrote the paper, and all authors provided feedback and have approved the final manuscript	wrote the paper, and all authors provided feedback and have approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5585965	28874116	KFO	2	generated rna libraries for sequencing|conducted data analysis and interpretation	generated rna libraries for sequencing	Performed the experiments	Investigation	YES
5585965	28874116	KFO	2	generated rna libraries for sequencing|conducted data analysis and interpretation	conducted data analysis and interpretation	Analyzed the data	Formal analysis	YES
5585965	28874116	MDD	2	oversaw the study and aided with interpretation and conclusions	oversaw the study and aided with interpretation and conclusions	Analyzed the data	Formal analysis|Supervision	YES
5585965	28874116	RBW	2	conducted data analysis and interpretation|oversaw the study and aided with interpretation and conclusions|wrote the paper, and all authors provided feedback and have approved the final manuscript	conducted data analysis and interpretation	Analyzed the data	Formal analysis	YES
5585965	28874116	RBW	2	conducted data analysis and interpretation|oversaw the study and aided with interpretation and conclusions|wrote the paper, and all authors provided feedback and have approved the final manuscript	oversaw the study and aided with interpretation and conclusions	Analyzed the data	Formal analysis|Supervision	YES
5585965	28874116	RBW	2	conducted data analysis and interpretation|oversaw the study and aided with interpretation and conclusions|wrote the paper, and all authors provided feedback and have approved the final manuscript	wrote the paper, and all authors provided feedback and have approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4798600	26989057	IM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/financing support/analysis tools|Preapared figures and tables	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4798600	26989057	IM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/financing support/analysis tools|Preapared figures and tables	Analyzed the data	Analyzed the data	Formal analysis	YES
4798600	26989057	IM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/financing support/analysis tools|Preapared figures and tables	Contributed reagents/materials/financing support/analysis tools	Contributed reagents/materials/analysis tools	Funding acquisition|Resources	YES
4798600	26989057	IM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/financing support/analysis tools|Preapared figures and tables	Preapared figures and tables	-	Visualization	YES
4798600	26989057	JT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/financing support/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4798600	26989057	JT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/financing support/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4798600	26989057	JT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/financing support/analysis tools	Contributed reagents/materials/financing support/analysis tools	Contributed reagents/materials/analysis tools	Funding acquisition|Resources	YES
4798600	26989057	TN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/financing support/analysis tools|Wrote main manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4798600	26989057	TN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/financing support/analysis tools|Wrote main manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4798600	26989057	TN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/financing support/analysis tools|Wrote main manuscript	Contributed reagents/materials/financing support/analysis tools	Contributed reagents/materials/analysis tools	Funding acquisition|Resources	YES
4798600	26989057	TN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/financing support/analysis tools|Wrote main manuscript	Wrote main manuscript	Wrote the paper	Writing - Original Draft	YES
4798600	26989057	YK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/financing support/analysis tools|Wrote main manuscript|Preapared figures and tables	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4798600	26989057	YK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/financing support/analysis tools|Wrote main manuscript|Preapared figures and tables	Performed the experiments	Performed the experiments	Investigation	YES
4798600	26989057	YK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/financing support/analysis tools|Wrote main manuscript|Preapared figures and tables	Analyzed the data	Analyzed the data	Formal analysis	YES
4798600	26989057	YK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/financing support/analysis tools|Wrote main manuscript|Preapared figures and tables	Contributed reagents/materials/financing support/analysis tools	Contributed reagents/materials/analysis tools	Funding acquisition|Resources	YES
4798600	26989057	YK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/financing support/analysis tools|Wrote main manuscript|Preapared figures and tables	Wrote main manuscript	Wrote the paper	Writing - Original Draft	YES
4798600	26989057	YK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/financing support/analysis tools|Wrote main manuscript|Preapared figures and tables	Preapared figures and tables	-	Visualization	YES
1888729	17579712	AK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1888729	17579712	AK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1888729	17579712	AK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1888729	17579712	DD	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1888729	17579712	EA	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1888729	17579712	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1888729	17579712	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1888729	17579712	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1888729	17579712	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1888729	17579712	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1888729	17579712	MM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414460	25923134	AF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414460	25923134	AF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414460	25923134	AF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414460	25923134	AF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414460	25923134	AGJ	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4414460	25923134	AGJ	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4414460	25923134	FPC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414460	25923134	FPC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4414460	25923134	FPC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414460	25923134	MAG	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414460	25923134	MAG	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414460	25923134	MAG	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414460	25923134	MAG	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414460	25923134	MC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414460	25923134	MC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414460	25923134	MC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414460	25923134	MC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5904095	29667074	EC	2	acquired the data|critically revised the manuscript	acquired the data	Performed the experiments	Investigation	YES
5904095	29667074	EC	2	acquired the data|critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5904095	29667074	KB	2	critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5904095	29667074	KEG	2	conceived and designed the study|acquired the data|drafted the manuscript|critically revised the manuscript|contributed to the statistical analysis	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5904095	29667074	KEG	2	conceived and designed the study|acquired the data|drafted the manuscript|critically revised the manuscript|contributed to the statistical analysis	acquired the data	Performed the experiments	Investigation	YES
5904095	29667074	KEG	2	conceived and designed the study|acquired the data|drafted the manuscript|critically revised the manuscript|contributed to the statistical analysis	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5904095	29667074	KEG	2	conceived and designed the study|acquired the data|drafted the manuscript|critically revised the manuscript|contributed to the statistical analysis	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5904095	29667074	KEG	2	conceived and designed the study|acquired the data|drafted the manuscript|critically revised the manuscript|contributed to the statistical analysis	contributed to the statistical analysis	Analyzed the data	Formal analysis	YES
5904095	29667074	KVL	2	conceived and designed the study|drafted the manuscript|critically revised the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5904095	29667074	KVL	2	conceived and designed the study|drafted the manuscript|critically revised the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5904095	29667074	KVL	2	conceived and designed the study|drafted the manuscript|critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5904095	29667074	LDC	2	acquired the data|drafted the manuscript|contributed to the statistical analysis	acquired the data	Performed the experiments	Investigation	YES
5904095	29667074	LDC	2	acquired the data|drafted the manuscript|contributed to the statistical analysis	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5904095	29667074	LDC	2	acquired the data|drafted the manuscript|contributed to the statistical analysis	contributed to the statistical analysis	Analyzed the data	Formal analysis	YES
5904095	29667074	PD	2	critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5904095	29667074	WVP	2	conceived and designed the study|acquired the data|critically revised the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5904095	29667074	WVP	2	conceived and designed the study|acquired the data|critically revised the manuscript	acquired the data	Performed the experiments	Investigation	YES
5904095	29667074	WVP	2	conceived and designed the study|acquired the data|critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4609334	26504780	Francesca Collina	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
4609334	26504780	Maurizio Di Bonito	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
3723652	23875823	DAT	2	were significant contributors to data acquisition and were important manuscript reviewers/revisers	were significant contributors to data acquisition and were important manuscript reviewers/revisers	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Resources|Writing - Review & Editing	YES
3723652	23875823	GOJ	2	were significant manuscript reviewers/revisers and were substantial contributors to conception and design of this study	were significant manuscript reviewers/revisers and were substantial contributors to conception and design of this study	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
3723652	23875823	HCB	2	were significant contributors to data acquisition and were important manuscript reviewers/revisers	were significant contributors to data acquisition and were important manuscript reviewers/revisers	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Resources|Writing - Review & Editing	YES
3723652	23875823	JTC	2	was the primary manuscript reviewer/reviser, a substantial contributor to concept and design, and contributed to data analysis and interpretation	was the primary manuscript reviewer/reviser, a substantial contributor to concept and design, and contributed to data analysis and interpretation	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Resources|Writing - Original Draft|Writing - Review & Editing	YES
3723652	23875823	KCC	2	were significant contributors to data acquisition and were important manuscript reviewers/revisers	were significant contributors to data acquisition and were important manuscript reviewers/revisers	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Resources|Writing - Review & Editing	YES
3723652	23875823	NDMJ	2	was the primary manuscript writer, and carried out data acquisition, data analysis and data interpretation	was the primary manuscript writer, and carried out data acquisition, data analysis and data interpretation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3723652	23875823	RJS	2	were significant manuscript reviewers/revisers and were substantial contributors to conception and design of this study	were significant manuscript reviewers/revisers and were substantial contributors to conception and design of this study	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
3723652	23875823	RWL	2	were significant contributors to data acquisition and were important manuscript reviewers/revisers	were significant contributors to data acquisition and were important manuscript reviewers/revisers	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Resources|Writing - Review & Editing	YES
3723652	23875823	TJH	2	were significant manuscript reviewers/revisers and were substantial contributors to conception and design of this study	were significant manuscript reviewers/revisers and were substantial contributors to conception and design of this study	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
5715336	29250081	All authors	2	substantially contributed to the work|commented on and edited the document and have approved the final submitted document	substantially contributed to the work	-	-	NO
5715336	29250081	All authors	2	substantially contributed to the work|commented on and edited the document and have approved the final submitted document	commented on and edited the document and have approved the final submitted document	Wrote the paper	Writing - Review & Editing	YES
5715336	29250081	BKS	2	made final editorial adjustments	made final editorial adjustments	-	-	NO
5715336	29250081	CL	2	made final editorial adjustments	made final editorial adjustments	-	-	NO
5715336	29250081	DFW	2	drafted the introduction	drafted the introduction	Wrote the paper	Writing - Original Draft	YES
5715336	29250081	ELGH	2	made final editorial adjustments	made final editorial adjustments	-	-	NO
5715336	29250081	FE	2	drafted the introduction|made final editorial adjustments	drafted the introduction	Wrote the paper	Writing - Original Draft	YES
5715336	29250081	FE	2	drafted the introduction|made final editorial adjustments	made final editorial adjustments	-	-	NO
5715336	29250081	HB	2	drafted the introduction|made final editorial adjustments	drafted the introduction	Wrote the paper	Writing - Original Draft	YES
5715336	29250081	HB	2	drafted the introduction|made final editorial adjustments	made final editorial adjustments	-	-	NO
5715336	29250081	HS	2	made final editorial adjustments	made final editorial adjustments	-	-	NO
5715336	29250081	JSC	2	made final editorial adjustments	made final editorial adjustments	-	-	NO
5585987	28874115	AHKR	2	analyzed part of the data	analyzed part of the data	Analyzed the data	Formal analysis	YES
5585987	28874115	CKK	2	supervised and monitored the experimental work	supervised and monitored the experimental work	Performed the experiments	Investigation|Supervision	YES
5585987	28874115	DJL	2	supervised and monitored the experimental work	supervised and monitored the experimental work	Performed the experiments	Investigation|Supervision	YES
5585987	28874115	ISN	2	supervised and monitored the experimental work	supervised and monitored the experimental work	Performed the experiments	Investigation|Supervision	YES
5585987	28874115	JIP	2	supervised and monitored the experimental work	supervised and monitored the experimental work	Performed the experiments	Investigation|Supervision	YES
5585987	28874115	KBL	2	supervised and monitored the experimental work	supervised and monitored the experimental work	Performed the experiments	Investigation|Supervision	YES
5585987	28874115	KK	2	designed the work and conducted the in silico analysis, grew the plants, isolated rna and carried out the expression analysis, and prepared a draft of the manuscript	designed the work and conducted the in silico analysis, grew the plants, isolated rna and carried out the expression analysis, and prepared a draft of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5585987	28874115	MBK	2	supervised and monitored the experimental work	supervised and monitored the experimental work	Performed the experiments	Investigation|Supervision	YES
5585987	28874115	MYC	2	designed and supervised the work	designed and supervised the work	Conceived and designed the experiments	Supervision	YES
5585987	28874115	UKN	2	analyzed the data and extensively revised the manuscript	analyzed the data and extensively revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
3726298	23514330	AJK	2	provided assay support, statistical and data analyses, and assisted with manuscript preparation	provided assay support, statistical and data analyses, and assisted with manuscript preparation	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft	YES
3726298	23514330	LAC	2	designed the study, secured funding, and was involved in the data collection and analysis, as well as manuscript preparation	designed the study, secured funding, and was involved in the data collection and analysis, as well as manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Funding acquisition|Investigation|Methodology|Writing - Original Draft	YES
3726298	23514330	RWK	2	assisted with both data and statistical analyses, and manuscript development	assisted with both data and statistical analyses, and manuscript development	Analyzed the data	Formal analysis	YES
4801823	27001438	AF	PLoS52	performed the experiments|drafted the manuscript	performed the experiments	Performed the experiments	Investigation	YES
4801823	27001438	AF	PLoS52	performed the experiments|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4801823	27001438	All authors	PLoS52	critically read and contributed to the final version of the manuscript|read and approved the final manuscript	critically read and contributed to the final version of the manuscript	-	-	NO
4801823	27001438	All authors	PLoS52	critically read and contributed to the final version of the manuscript|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4801823	27001438	GP	PLoS52	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
4801823	27001438	MV	PLoS52	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
4801823	27001438	NC	PLoS52	designed the experiments|performed the experiments|drafted the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
4801823	27001438	NC	PLoS52	designed the experiments|performed the experiments|drafted the manuscript	performed the experiments	Performed the experiments	Investigation	YES
4801823	27001438	NC	PLoS52	designed the experiments|performed the experiments|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4801823	27001438	VC	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
4414461	25923584	DFS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414461	25923584	DFS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414461	25923584	DFS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414461	25923584	DFS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414461	25923584	DFS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414461	25923584	FD	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4414461	25923584	GEB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414461	25923584	GEB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414461	25923584	GEB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414461	25923584	JC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414461	25923584	JC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414461	25923584	MJR	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4414461	25923584	MLJ	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4414461	25923584	MLJ	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4414461	25923584	MTV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414461	25923584	MTV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414461	25923584	MTV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414461	25923584	MTV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414461	25923584	MTV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414461	25923584	PCF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414461	25923584	PCF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414461	25923584	PCF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414461	25923584	PCF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414461	25923584	PCF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414461	25923584	PET	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4414461	25923584	PET	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1888730	17565384	QW	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1888730	17565384	QW	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1888730	17565384	QW	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1888730	17565384	YP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1888730	17565384	YP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1888730	17565384	YP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5930298	29717383	CT	2	carried out the animal surgical procedures, maintained the physiological condition of the animals, carried out the pet scans and data analysis, discussed and interpreted the data and findings, and drafted the manuscript	carried out the animal surgical procedures, maintained the physiological condition of the animals, carried out the pet scans and data analysis, discussed and interpreted the data and findings, and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5930298	29717383	HS	2	conceived of the study, participated in its design and coordination, and helped to draft the manuscript	conceived of the study, participated in its design and coordination, and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
5930298	29717383	HY	2	carried out the pet scans and data analysis, and participated in the sequence alignment	carried out the pet scans and data analysis, and participated in the sequence alignment	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5930298	29717383	KK	2	discussed and interpreted the data and findings, and participated in the sequence alignment	discussed and interpreted the data and findings, and participated in the sequence alignment	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5930298	29717383	MK	2	discussed and interpreted the data and findings, and participated in the sequence alignment	discussed and interpreted the data and findings, and participated in the sequence alignment	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5930298	29717383	NN	2	discussed and interpreted the data and findings, and participated in the sequence alignment	discussed and interpreted the data and findings, and participated in the sequence alignment	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5930298	29717383	NT	2	discussed and interpreted the data and findings, and participated in the sequence alignment	discussed and interpreted the data and findings, and participated in the sequence alignment	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5930298	29717383	NU	2	carried out the pet scans and data analysis, and participated in the sequence alignment	carried out the pet scans and data analysis, and participated in the sequence alignment	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5930298	29717383	SZ	2	carried out the pet scans and data analysis and participated in the design of the study	carried out the pet scans and data analysis and participated in the design of the study	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5930298	29717383	TA	2	discussed and interpreted the data and findings, and participated in the sequence alignment	discussed and interpreted the data and findings, and participated in the sequence alignment	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5930298	29717383	YK	2	carried out the pet scans and data analysis, and participated in the design of the study	carried out the pet scans and data analysis, and participated in the design of the study	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5930298	29717383	ZW	2	carried out the animal surgical procedures, maintained the physiological condition of the animals, and participated in the sequence alignment	carried out the animal surgical procedures, maintained the physiological condition of the animals, and participated in the sequence alignment	Performed the experiments	Investigation	YES
3733607	23875791	APXL	2	collected data, organized and built the first drafts of the manuscript	collected data, organized and built the first drafts of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3733607	23875791	BR	2	joined to help improve discussion	joined to help improve discussion	-	-	NO
3733607	23875791	CEC	2	collected data, organized and built the first drafts of the manuscript	collected data, organized and built the first drafts of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3733607	23875791	ECC	2	collected data, organized and built the first drafts of the manuscript	collected data, organized and built the first drafts of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3733607	23875791	EF	2	collected data, organized and built the first drafts of the manuscript	collected data, organized and built the first drafts of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3733607	23875791	FSL	2	joined to help improve discussion	joined to help improve discussion	-	-	NO
3733607	23875791	HAPB	2	collected data, organized and built the first drafts of the manuscript	collected data, organized and built the first drafts of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3733607	23875791	IRD	2	collected data, organized and built the first drafts of the manuscript	collected data, organized and built the first drafts of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3733607	23875791	SCC	2	collected data, organized and built the first drafts of the manuscript	collected data, organized and built the first drafts of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5715367	29250089	All authors	2	discussed the results and provided input on the manuscript	discussed the results and provided input on the manuscript	-	-	NO
5715367	29250089	EV	2	performed the phenotyping analyses	performed the phenotyping analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5715367	29250089	TE	2	target selection	target selection	-	-	NO
5940985	29740722	CL	2	reviewed the patient notes to establish the reference diagnosis and reviewed the manuscript	reviewed the patient notes to establish the reference diagnosis and reviewed the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5940985	29740722	CR	2	participated in the reporting study and reviewed the manuscript	participated in the reporting study and reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5940985	29740722	EL	2	participated in the reporting study and reviewed the manuscript	participated in the reporting study and reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5940985	29740722	JF	2	provided guidance on the study design and reviewed the manuscript	provided guidance on the study design and reviewed the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Review & Editing	YES
5940985	29740722	JT	2	designed the study, wrote the software, collected the data from the reporting study and wrote the manuscript	designed the study, wrote the software, collected the data from the reporting study and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Methodology|Software|Writing - Original Draft	YES
5940985	29740722	OB	2	reviewed the patient notes to establish the reference diagnosis, provided guidance on data collection and reviewed the manuscript	reviewed the patient notes to establish the reference diagnosis, provided guidance on data collection and reviewed the manuscript	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Resources|Supervision|Writing - Review & Editing	YES
4801825	27001439	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4801825	27001439	CC	2	produced the enzymatic cocktails in bioreactors	produced the enzymatic cocktails in bioreactors	-	-	NO
4801825	27001439	CR	2	designed the enzymatic hydrolysis experiments|analyzed all results|drafted the manuscript	designed the enzymatic hydrolysis experiments	Conceived and designed the experiments	Methodology	YES
4801825	27001439	CR	2	designed the enzymatic hydrolysis experiments|analyzed all results|drafted the manuscript	analyzed all results	Analyzed the data	Formal analysis	YES
4801825	27001439	CR	2	designed the enzymatic hydrolysis experiments|analyzed all results|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4801825	27001439	ED	2	performed the enzymatic hydrolysis experiments and quantified the sugars produced	performed the enzymatic hydrolysis experiments and quantified the sugars produced	Performed the experiments	Investigation	YES
4801825	27001439	FBC	2	designed the experiments for the production of the various enzymatic cocktails|analyzed all results	designed the experiments for the production of the various enzymatic cocktails	Conceived and designed the experiments	Methodology	YES
4801825	27001439	FBC	2	designed the experiments for the production of the various enzymatic cocktails|analyzed all results	analyzed all results	Analyzed the data	Formal analysis	YES
4801825	27001439	JT	2	designed the enzymatic hydrolysis experiments|analyzed all results	designed the enzymatic hydrolysis experiments	Conceived and designed the experiments	Methodology	YES
4801825	27001439	JT	2	designed the enzymatic hydrolysis experiments|analyzed all results	analyzed all results	Analyzed the data	Formal analysis	YES
4801825	27001439	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5586008	28877683	AL	2	contributed to collecting samples and measuring phenotypic data	contributed to collecting samples and measuring phenotypic data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5586008	28877683	CS	2	conceived the study and designed the project|revised the manuscript	conceived the study and designed the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5586008	28877683	CS	2	conceived the study and designed the project|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5586008	28877683	FS	2	contributed to collecting samples and measuring phenotypic data	contributed to collecting samples and measuring phenotypic data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5586008	28877683	GW	2	contributed to collecting samples and measuring phenotypic data	contributed to collecting samples and measuring phenotypic data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5586008	28877683	JY	2	performed genetic, bioinformatics and molecular analyses|contributed to collecting samples and measuring phenotypic data|wrote the manuscript	performed genetic, bioinformatics and molecular analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5586008	28877683	JY	2	performed genetic, bioinformatics and molecular analyses|contributed to collecting samples and measuring phenotypic data|wrote the manuscript	contributed to collecting samples and measuring phenotypic data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5586008	28877683	JY	2	performed genetic, bioinformatics and molecular analyses|contributed to collecting samples and measuring phenotypic data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5586008	28877683	NY	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5586008	28877683	SC	2	contributed to collecting samples and measuring phenotypic data	contributed to collecting samples and measuring phenotypic data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
1890305	17579718	HC	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1890305	17579718	HC	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1890305	17579718	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1890305	17579718	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1890305	17579718	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1890305	17579718	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1890305	17579718	NH	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1890305	17579718	SW	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1890305	17579718	SW	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3750261	23914839	IE	2	assisted in coordination and helped to draft the manuscript	assisted in coordination and helped to draft the manuscript	Wrote the paper	Project administration|Writing - Original Draft	YES
4414462	25923822	FG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414462	25923822	FG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414462	25923822	FG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414462	25923822	FG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414462	25923822	FZ	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414462	25923822	FZ	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414462	25923822	Hongjie Li	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414462	25923822	Huayun Li	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4414462	25923822	JF	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414462	25923822	JF	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414462	25923822	JW	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4414462	25923822	NW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4414462	25923822	SW	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414462	25923822	SW	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414462	25923822	YZ	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414462	25923822	YZ	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414462	25923822	ZL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5943199	29744748	AS	2	was the principal investigator of the study and also in charge of subject recruitment, routine measurements	was the principal investigator of the study and also in charge of subject recruitment, routine measurements	Conceived and designed the experiments|Performed the experiments	Conceptualization|Funding acquisition|Investigation	YES
5943199	29744748	BF	2	carried out the mri imaging evaluation	carried out the mri imaging evaluation	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
5943199	29744748	BKG	2	was in charge of the subject recruitment and study coordination	was in charge of the subject recruitment and study coordination	Performed the experiments	Investigation|Project administration	YES
5943199	29744748	LP	2	developed the machine learning algorithm and performed the according evaluations	developed the machine learning algorithm and performed the according evaluations	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Software	YES
5943199	29744748	LS	2	performed the partial volume correction procedure and participated in the manuscript writing	performed the partial volume correction procedure and participated in the manuscript writing	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5943199	29744748	MH	2	participated in the subject treatment and were in charge of the routine measurements|was the head of the study and in charge of the study coordination, and he helped to draft the manuscript	participated in the subject treatment and were in charge of the routine measurements	Performed the experiments	Investigation	YES
5943199	29744748	MH	2	participated in the subject treatment and were in charge of the routine measurements|was the head of the study and in charge of the study coordination, and he helped to draft the manuscript	was the head of the study and in charge of the study coordination, and he helped to draft the manuscript	Wrote the paper	Project administration|Writing - Original Draft	YES
5943199	29744748	PB	2	was in charge of the coordination of the mri protocol and the mri imaging evaluation	was in charge of the coordination of the mri protocol and the mri imaging evaluation	Conceived and designed the experiments|Analyzed the data	Methodology|Project administration|Visualization	YES
5943199	29744748	PET	2	imaging evaluation, and drafting the manuscript	imaging evaluation, and drafting the manuscript	Analyzed the data|Wrote the paper	Visualization|Writing - Original Draft	YES
5943199	29744748	SR	2	participated in the subject treatment and were in charge of the routine measurements	participated in the subject treatment and were in charge of the routine measurements	Performed the experiments	Investigation	YES
5943199	29744748	TN	2	participated in the subject treatment and were in charge of the routine measurements	participated in the subject treatment and were in charge of the routine measurements	Performed the experiments	Investigation	YES
4805677	27009074	AR	2	carried out the fungal taxonomic characterization	carried out the fungal taxonomic characterization	Performed the experiments	Investigation	YES
4805677	27009074	AV	2	carried out the fungal taxonomic characterization	carried out the fungal taxonomic characterization	Performed the experiments	Investigation	YES
4805677	27009074	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4805677	27009074	JAS	2	carried out the studies related to the xylanase production and drafted the manuscript	carried out the studies related to the xylanase production and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4805677	27009074	JMFV	2	participated in the xylanase activity assay and enzymatic characterization	participated in the xylanase activity assay and enzymatic characterization	Performed the experiments	Investigation	YES
4805677	27009074	LAM	2	carried out the fungal taxonomic characterization	carried out the fungal taxonomic characterization	Performed the experiments	Investigation	YES
4805677	27009074	LDS	2	contributed in data interpretation, coordination and manuscript revision	contributed in data interpretation, coordination and manuscript revision	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Project administration|Resources|Writing - Review & Editing	YES
4805677	27009074	MHT	2	carried out the studies related to the evaluation of toxic properties	carried out the studies related to the evaluation of toxic properties	Performed the experiments	Investigation	YES
5715369	29250087	BM	2	supervised the research	supervised the research	-	Supervision	YES
5715369	29250087	BT	2	provided technical assistance	provided technical assistance	Performed the experiments	Investigation	YES
5715369	29250087	GW	2	performed the semi-thin sections	performed the semi-thin sections	Performed the experiments	Investigation	YES
5715369	29250087	JT	2	finished the subcellular localization analysis	finished the subcellular localization analysis	Performed the experiments	Investigation	YES
5715369	29250087	LD	2	performed most of the experiments and wrote the manuscript	performed most of the experiments and wrote the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5715369	29250087	ML	2	performed rt-qpcr analyses and complementation test	performed rt-qpcr analyses and complementation test	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5715369	29250087	PQ	2	supervised and complemented the writing	supervised and complemented the writing	Wrote the paper	Supervision	YES
5715369	29250087	SF	2	finished the subcellular localization analysis	finished the subcellular localization analysis	Performed the experiments	Investigation	YES
5715369	29250087	SL	2	supervised the research	supervised the research	-	Supervision	YES
5715369	29250087	SZ	2	performed rt-qpcr analyses and complementation test	performed rt-qpcr analyses and complementation test	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5715369	29250087	WC	2	finished the subcellular localization analysis	finished the subcellular localization analysis	Performed the experiments	Investigation	YES
5715369	29250087	YW	2	supervised the research	supervised the research	-	Supervision	YES
3750511	23919405	JA	2	contributed significantly to all aspects of this study	contributed significantly to all aspects of this study	-	-	NO
3750511	23919405	VC	2	contributed significantly to all aspects of this study	contributed significantly to all aspects of this study	-	-	NO
1890306	17579719	CP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1890306	17579719	CP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1890306	17579719	CP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1890306	17579719	CP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1890306	17579719	CP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1890306	17579719	DC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1890306	17579719	DC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1890306	17579719	DC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1890306	17579719	DC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1890306	17579719	GP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1890306	17579719	GP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1890306	17579719	GP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1890306	17579719	PD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1890306	17579719	PD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1890306	17579719	PD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1890306	17579719	PD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1890306	17579719	PD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1890306	17579719	PH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1890306	17579719	PH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1890306	17579719	PH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1890306	17579719	PH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414466	25923338	CFC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414466	25923338	CFC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414466	25923338	HYY	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414466	25923338	HYY	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414466	25923338	HYY	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414466	25923338	LSC	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414466	25923338	LSC	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414466	25923338	THL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414466	25923338	THL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414466	25923338	THL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414466	25923338	THL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414466	25923338	THL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5588707	28877665	GPHvH	2	designed the study, performed some experiments and prepared the manuscript	designed the study, performed some experiments and prepared the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5588707	28877665	JMHT	2	carried out most of the experiments and contributed to writing the manuscript	carried out most of the experiments and contributed to writing the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5588707	28877665	MEC	2	carried out most of the experiments and contributed to writing the manuscript	carried out most of the experiments and contributed to writing the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5588707	28877665	PPPT	2	analyzed the effect of an additional copy pho4	analyzed the effect of an additional copy pho4	Analyzed the data	Formal analysis	YES
3750722	23914797	ESR	2	participated in data collection, data analysis, and the writing of the manuscript	participated in data collection, data analysis, and the writing of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3750722	23914797	MJD	2	designed the study and supervised the data collection, analysis, and interpretation|also supervised the writing of the manuscript	designed the study and supervised the data collection, analysis, and interpretation	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology|Supervision	YES
3750722	23914797	MJD	2	designed the study and supervised the data collection, analysis, and interpretation|also supervised the writing of the manuscript	also supervised the writing of the manuscript	Wrote the paper	Supervision|Writing - Original Draft	YES
3750722	23914797	MPO	2	helped with data collection and contributed to the writing of the manuscript	helped with data collection and contributed to the writing of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3750722	23914797	NIW	2	designed the study and supervised the data collection, analysis, and interpretation	designed the study and supervised the data collection, analysis, and interpretation	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology|Supervision	YES
3750722	23914797	RJM	2	was responsible for data collection, data analysis and interpretation, and the writing of the manuscript	was responsible for data collection, data analysis and interpretation, and the writing of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5715382	29250082	AH	2	designed and supervised the physiological experiments and participated in interpreting the morpho-physiological data	designed and supervised the physiological experiments and participated in interpreting the morpho-physiological data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology|Supervision	YES
5715382	29250082	AK	2	together conceptualized and supervised the whole study as well as participated in writing the manuscript	together conceptualized and supervised the whole study as well as participated in writing the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Supervision|Writing - Original Draft	YES
5715382	29250082	BH	2	performed the plant hormone measurements and participated in manuscript writing	performed the plant hormone measurements and participated in manuscript writing	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5715382	29250082	MB	2	performed the cell wall metabolite analysis and its interpretation, respectively	performed the cell wall metabolite analysis and its interpretation, respectively	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5715382	29250082	MLR	2	helped in sampling plant materials, performed transcript analysis of aoc and opr7 , interpreted the proteome and metabolite data and participated in writing the manuscript	helped in sampling plant materials, performed transcript analysis of aoc and opr7 , interpreted the proteome and metabolite data and participated in writing the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5715382	29250082	MR	2	together conceptualized and supervised the whole study as well as participated in writing the manuscript	together conceptualized and supervised the whole study as well as participated in writing the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Supervision|Writing - Original Draft	YES
5715382	29250082	MS	2	bioinformatics analysis for the root proteomics data	bioinformatics analysis for the root proteomics data	Analyzed the data	Formal analysis	YES
5715382	29250082	PP	2	performed the qrt-pcr analysis of genes related to phenylpropanoid pathway	performed the qrt-pcr analysis of genes related to phenylpropanoid pathway	Performed the experiments	Investigation	YES
5715382	29250082	RD	2	performed the morpho-physiological characterization experiments, generated all plant sampling material, prepared rna and protein samples, performed tmt labeling experiments, analyzed and interpreted the morpho-physiological, cell wall metabolite and root proteome results, and wrote the manuscript	performed the morpho-physiological characterization experiments, generated all plant sampling material, prepared rna and protein samples, performed tmt labeling experiments, analyzed and interpreted the morpho-physiological, cell wall metabolite and root proteome results, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5715382	29250082	RS	2	performed the cell wall metabolite analysis and its interpretation, respectively	performed the cell wall metabolite analysis and its interpretation, respectively	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5715382	29250082	VS	2	performed the root histological studies	performed the root histological studies	Performed the experiments	Investigation	YES
1890307	17579714	AT	PLoS5	Performed the experiments|Contributed to blood processing and immunological and virological analyses	Performed the experiments	Performed the experiments	Investigation	YES
1890307	17579714	AT	PLoS5	Performed the experiments|Contributed to blood processing and immunological and virological analyses	Contributed to blood processing and immunological and virological analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
1890307	17579714	HI	PLoS5	Performed the experiments|Contributed to blood processing and immunological and virological analyses	Performed the experiments	Performed the experiments	Investigation	YES
1890307	17579714	HI	PLoS5	Performed the experiments|Contributed to blood processing and immunological and virological analyses	Contributed to blood processing and immunological and virological analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
1890307	17579714	HY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1890307	17579714	HY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1890307	17579714	HY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1890307	17579714	HY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1890307	17579714	MK	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Contributed to immunological analyses	Performed the experiments	Performed the experiments	Investigation	YES
1890307	17579714	MK	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Contributed to immunological analyses	Analyzed the data	Analyzed the data	Formal analysis	YES
1890307	17579714	MK	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Contributed to immunological analyses	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1890307	17579714	MK	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Contributed to immunological analyses	Contributed to immunological analyses	Analyzed the data	Formal analysis	YES
1890307	17579714	TM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1890307	17579714	TM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1890307	17579714	TM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1890307	17579714	TM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5953910	29766311	FH	2	performed the data evaluation, designed the study, and wrote the manuscript|shared the first authorship	performed the data evaluation, designed the study, and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5953910	29766311	FH	2	performed the data evaluation, designed the study, and wrote the manuscript|shared the first authorship	shared the first authorship	-	-	NO
5953910	29766311	IA	2	contributed to the patient data, contributed to data assessment, and reviewed the manuscript	contributed to the patient data, contributed to data assessment, and reviewed the manuscript	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Review & Editing	YES
5953910	29766311	JK	2	contributed to the patient data, contributed to data assessment, and reviewed the manuscript	contributed to the patient data, contributed to data assessment, and reviewed the manuscript	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Review & Editing	YES
5953910	29766311	JM	2	performed the data evaluation, designed the study, and wrote the manuscript|shared the first authorship	performed the data evaluation, designed the study, and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5953910	29766311	JM	2	performed the data evaluation, designed the study, and wrote the manuscript|shared the first authorship	shared the first authorship	-	-	NO
5953910	29766311	JvdH	2	performed the data evaluation, designed the study, and wrote the manuscript	performed the data evaluation, designed the study, and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5953910	29766311	MCK	2	contributed to the patient data, contributed to data assessment, and reviewed the manuscript	contributed to the patient data, contributed to data assessment, and reviewed the manuscript	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Review & Editing	YES
4808072	27015845	AH	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4808072	27015845	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4808072	27015845	DSMZ	2	analyzed, interpreted and discussed the whole laboratory data	analyzed, interpreted and discussed the whole laboratory data	Analyzed the data	Formal analysis	YES
4808072	27015845	YH	2	conducted some of the experimental laboratory work	conducted some of the experimental laboratory work	Performed the experiments	Investigation	YES
4414467	25923776	JJF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414467	25923776	JJF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414467	25923776	JJF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414467	25923776	JJF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414467	25923776	ZJT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414467	25923776	ZJT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414467	25923776	ZJT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414467	25923776	ZJT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414467	25923776	ZJT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3750820	23924268	Each author	2	contributed significantly to the successful carriage of this study	contributed significantly to the successful carriage of this study	-	-	NO
3750820	23924268	JT	2	coordinated the irb approval, subject visits, and sample inventory	coordinated the irb approval, subject visits, and sample inventory	-	Project administration	YES
3750820	23924268	MP	2	participated in the study design and coordination of subject visits	participated in the study design and coordination of subject visits	Conceived and designed the experiments	Methodology|Project administration	YES
3750820	23924268	ST	2	designed the study and drafted the manuscript	designed the study and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5588714	28877662	EH	CRediT	Experimental validation	Experimental validation	Performed the experiments	Validation	YES
5588714	28877662	JX	CRediT	Conceptualization	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
5588714	28877662	XL	CRediT	Conceptualization	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
5588714	28877662	YL	CRediT	Conceptualization	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
5588714	28877662	ZL	CRediT	Experimental validation	Experimental validation	Performed the experiments	Validation	YES
1890308	17579717	DB	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1890308	17579717	DB	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1890308	17579717	FO	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1890308	17579717	FO	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1890308	17579717	KJ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1890308	17579717	LP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1890308	17579717	NB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1890308	17579717	SS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1890308	17579717	SS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1890308	17579717	TL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1890308	17579717	ZO	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1890308	17579717	ZO	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
3751771	23958337	DT	2	supported data collection, provided quality assurance and database management, conducted the secondary analyses, then wrote and edited the overall manuscript	supported data collection, provided quality assurance and database management, conducted the secondary analyses, then wrote and edited the overall manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Data curation|Formal analysis|Investigation|Resources|Software|Validation|Writing - Original Draft|Writing - Review & Editing	YES
3751771	23958337	HMK	2	wrote the funding proposal, managed the implementation of the overall study and edited the manuscript|to design the healthy eating component of the trial, including instrument selection and analysis and edited the manuscript	wrote the funding proposal, managed the implementation of the overall study and edited the manuscript	Performed the experiments|Wrote the paper	Funding acquisition|Investigation|Project administration|Writing - Original Draft|Writing - Review & Editing	YES
3751771	23958337	HMK	2	wrote the funding proposal, managed the implementation of the overall study and edited the manuscript|to design the healthy eating component of the trial, including instrument selection and analysis and edited the manuscript	to design the healthy eating component of the trial, including instrument selection and analysis and edited the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
3751771	23958337	PJN	2	wrote the funding proposal, managed the implementation of the overall study and edited the manuscript|helped develop the research question and also supervised the analysis of the data|to design the healthy eating component of the trial, including instrument selection and analysis and edited the manuscript	wrote the funding proposal, managed the implementation of the overall study and edited the manuscript	Performed the experiments|Wrote the paper	Funding acquisition|Investigation|Project administration|Writing - Original Draft|Writing - Review & Editing	YES
3751771	23958337	PJN	2	wrote the funding proposal, managed the implementation of the overall study and edited the manuscript|helped develop the research question and also supervised the analysis of the data|to design the healthy eating component of the trial, including instrument selection and analysis and edited the manuscript	helped develop the research question and also supervised the analysis of the data	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Supervision	YES
3751771	23958337	PJN	2	wrote the funding proposal, managed the implementation of the overall study and edited the manuscript|helped develop the research question and also supervised the analysis of the data|to design the healthy eating component of the trial, including instrument selection and analysis and edited the manuscript	to design the healthy eating component of the trial, including instrument selection and analysis and edited the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
3751771	23958337	SC	2	developed the research question, conducted the preliminary analysis and edited the manuscript	developed the research question, conducted the preliminary analysis and edited the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
4414468	25923664	AM	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4414468	25923664	AWT	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414468	25923664	AWT	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414468	25923664	EDG	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414468	25923664	EDG	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414468	25923664	SC	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414468	25923664	ZS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414468	25923664	ZS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414468	25923664	ZS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3751232	23977642	Adrian Jacques Ambrose	2	contributed to data analysis, interpretation, literature review and writing of this article	contributed to data analysis, interpretation, literature review and writing of this article	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
3751232	23977642	Helene Starks	2	contributed to data analysis, interpretation, literature review and writing of this article	contributed to data analysis, interpretation, literature review and writing of this article	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
3751232	23977642	Marjorie M. Mau	2	contributed to the research idea, study design and implementation, data collection, analysis, interpretation and writing of this article	contributed to the research idea, study design and implementation, data collection, analysis, interpretation and writing of this article	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
3751232	23977642	Rebecca Delafield	2	contributed to the study implementation, data collection, interpretation and writing of this article	contributed to the study implementation, data collection, interpretation and writing of this article	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft	YES
3751232	23977642	Vanessa Hiratsuka	2	contributed to study design, implementation, data collection, interpretation and writing of this article	contributed to study design, implementation, data collection, interpretation and writing of this article	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
5715398	29250083	MD	2	contributed to data analysis, interpretation of data and final approval of the version	contributed to data analysis, interpretation of data and final approval of the version	Analyzed the data	Formal analysis	YES
5715398	29250083	MH	2	contributed to the conception or design of the work, data analysis, interpretation of data and final approval of the version	contributed to the conception or design of the work, data analysis, interpretation of data and final approval of the version	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Resources	YES
5715398	29250083	TN	2	contributed to the conception or design of the work, collect data, data analysis, interpretation of data and writing of manuscript	contributed to the conception or design of the work, collect data, data analysis, interpretation of data and writing of manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Resources|Writing - Original Draft	YES
4816098	26847340	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4816098	26847340	CECP	2	did the experimental design and manuscript writing	did the experimental design and manuscript writing	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
4816098	26847340	DSA	2	did the experimental design and manuscript writing	did the experimental design and manuscript writing	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
4816098	26847340	FZG	2	performed microalga growth and all other analyse	performed microalga growth and all other analyse	Performed the experiments	Investigation	YES
4816098	26847340	HRS	2	did the experimental design and manuscript writing|performed microalga growth and all other analyse	did the experimental design and manuscript writing	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
4816098	26847340	HRS	2	did the experimental design and manuscript writing|performed microalga growth and all other analyse	performed microalga growth and all other analyse	Performed the experiments	Investigation	YES
4816098	26847340	VHM	2	performed microalga growth and all other analyse	performed microalga growth and all other analyse	Performed the experiments	Investigation	YES
5970127	29802556	ADW	PLoS52	designed the experiments|performed the animal experiments|supervised the project	designed the experiments	Conceived and designed the experiments	Methodology	YES
5970127	29802556	ADW	PLoS52	designed the experiments|performed the animal experiments|supervised the project	performed the animal experiments	Performed the experiments	Investigation	YES
5970127	29802556	ADW	PLoS52	designed the experiments|performed the animal experiments|supervised the project	supervised the project	-	Supervision	YES
5970127	29802556	AL	PLoS52	supervised the project	supervised the project	-	Supervision	YES
5970127	29802556	All authors	PLoS52	analysed the data|proofread the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
5970127	29802556	All authors	PLoS52	analysed the data|proofread the manuscript	proofread the manuscript	-	-	NO
5970127	29802556	BD	PLoS52	designed the experiments|supervised the project	designed the experiments	Conceived and designed the experiments	Methodology	YES
5970127	29802556	BD	PLoS52	designed the experiments|supervised the project	supervised the project	-	Supervision	YES
5970127	29802556	BvdW	PLoS52	designed the experiments|performed the chemical synthesis and radiosynthesis|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5970127	29802556	BvdW	PLoS52	designed the experiments|performed the chemical synthesis and radiosynthesis|wrote the manuscript	performed the chemical synthesis and radiosynthesis	Performed the experiments	Investigation	YES
5970127	29802556	BvdW	PLoS52	designed the experiments|performed the chemical synthesis and radiosynthesis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5970127	29802556	EK	PLoS52	performed the animal experiments	performed the animal experiments	Performed the experiments	Investigation	YES
5970127	29802556	JGJMB	PLoS52	performed the qpcr and histochemistry experiments	performed the qpcr and histochemistry experiments	Performed the experiments	Investigation	YES
5970127	29802556	JJB	PLoS52	performed the qpcr and histochemistry experiments	performed the qpcr and histochemistry experiments	Performed the experiments	Investigation	YES
5970127	29802556	MW	PLoS52	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5970127	29802556	RP	PLoS52	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5970127	29802556	WB	PLoS52	performed the animal experiments	performed the animal experiments	Performed the experiments	Investigation	YES
3827986	24195702	HN	1	Data acquisition|Data analysis and interpretation	Data acquisition	Performed the experiments	Investigation	YES
3827986	24195702	HN	1	Data acquisition|Data analysis and interpretation	Data analysis and interpretation	Analyzed the data	Formal analysis	YES
3827986	24195702	HO	1	Significant manuscript writer|Concept and design|Data analysis and interpretation|Significant manuscript reviewer/reviser	Significant manuscript writer	Wrote the paper	Writing - Original Draft	YES
3827986	24195702	HO	1	Significant manuscript writer|Concept and design|Data analysis and interpretation|Significant manuscript reviewer/reviser	Concept and design	Conceived and designed the experiments	Conceptualization	YES
3827986	24195702	HO	1	Significant manuscript writer|Concept and design|Data analysis and interpretation|Significant manuscript reviewer/reviser	Data analysis and interpretation	Analyzed the data	Formal analysis	YES
3827986	24195702	HO	1	Significant manuscript writer|Concept and design|Data analysis and interpretation|Significant manuscript reviewer/reviser	Significant manuscript reviewer/reviser	Wrote the paper	Writing - Review & Editing	YES
3827986	24195702	KI	1	Data acquisition|Data analysis and interpretation	Data acquisition	Performed the experiments	Investigation	YES
3827986	24195702	KI	1	Data acquisition|Data analysis and interpretation	Data analysis and interpretation	Analyzed the data	Formal analysis	YES
3827986	24195702	SGR	1	Significant manuscript writer|Concept and design|Data acquisition|Data analysis and interpretation	Significant manuscript writer	Wrote the paper	Writing - Original Draft	YES
3827986	24195702	SGR	1	Significant manuscript writer|Concept and design|Data acquisition|Data analysis and interpretation	Concept and design	Conceived and designed the experiments	Conceptualization	YES
3827986	24195702	SGR	1	Significant manuscript writer|Concept and design|Data acquisition|Data analysis and interpretation	Data acquisition	Performed the experiments	Investigation	YES
3827986	24195702	SGR	1	Significant manuscript writer|Concept and design|Data acquisition|Data analysis and interpretation	Data analysis and interpretation	Analyzed the data	Formal analysis	YES
3827986	24195702	SK	1	Data acquisition|Data analysis and interpretation	Data acquisition	Performed the experiments	Investigation	YES
3827986	24195702	SK	1	Data acquisition|Data analysis and interpretation	Data analysis and interpretation	Analyzed the data	Formal analysis	YES
3827986	24195702	SM	1	Concept and design|Significant manuscript reviewer/reviser	Concept and design	Conceived and designed the experiments	Conceptualization	YES
3827986	24195702	SM	1	Concept and design|Significant manuscript reviewer/reviser	Significant manuscript reviewer/reviser	Wrote the paper	Writing - Review & Editing	YES
3827986	24195702	TM	1	Significant manuscript writer|Concept and design|Data acquisition|Data analysis and interpretation	Significant manuscript writer	Wrote the paper	Writing - Original Draft	YES
3827986	24195702	TM	1	Significant manuscript writer|Concept and design|Data acquisition|Data analysis and interpretation	Concept and design	Conceived and designed the experiments	Conceptualization	YES
3827986	24195702	TM	1	Significant manuscript writer|Concept and design|Data acquisition|Data analysis and interpretation	Data acquisition	Performed the experiments	Investigation	YES
3827986	24195702	TM	1	Significant manuscript writer|Concept and design|Data acquisition|Data analysis and interpretation	Data analysis and interpretation	Analyzed the data	Formal analysis	YES
3827986	24195702	YM	1	Concept and design|Significant manuscript reviewer/reviser	Concept and design	Conceived and designed the experiments	Conceptualization	YES
3827986	24195702	YM	1	Concept and design|Significant manuscript reviewer/reviser	Significant manuscript reviewer/reviser	Wrote the paper	Writing - Review & Editing	YES
3827986	24195702	YN	1	Data analysis and interpretation|Statistical expertise	Data analysis and interpretation	Analyzed the data	Formal analysis	YES
3827986	24195702	YN	1	Data analysis and interpretation|Statistical expertise	Statistical expertise	Analyzed the data	Formal analysis	YES
4414469	25923325	LS	PLoS5	Analyzed the data|Edited the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4414469	25923325	LS	PLoS5	Analyzed the data|Edited the manuscript	Edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
4414469	25923325	MLP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414469	25923325	MLP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414469	25923325	MLP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414469	25923325	MLP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414469	25923325	MLP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414469	25923325	PDT-S	PLoS5	Conceived and designed the experiments|Analyzed the data|Edited the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414469	25923325	PDT-S	PLoS5	Conceived and designed the experiments|Analyzed the data|Edited the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4414469	25923325	PDT-S	PLoS5	Conceived and designed the experiments|Analyzed the data|Edited the manuscript	Edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
4414469	25923325	SJW	PLoS5	Conceived and designed the experiments|Analyzed the data|Edited the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414469	25923325	SJW	PLoS5	Conceived and designed the experiments|Analyzed the data|Edited the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4414469	25923325	SJW	PLoS5	Conceived and designed the experiments|Analyzed the data|Edited the manuscript	Edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
1891084	17579726	DB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1891084	17579726	DB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1891084	17579726	DB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1891084	17579726	DB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1891084	17579726	DB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1891084	17579726	LP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1891084	17579726	LP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1891084	17579726	LP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1891084	17579726	LP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1891084	17579726	LP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1891084	17579726	PA	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1891084	17579726	PA	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1891084	17579726	SM	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1891084	17579726	SM	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1891084	17579726	SP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1891084	17579726	SP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1891084	17579726	SP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1891084	17579726	SP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1891084	17579726	SP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5591509	28886704	AJW	2	helped analyze data and assisted in writing the manuscript	helped analyze data and assisted in writing the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5591509	28886704	ES	2	contributed lab space and assisted in writing the manuscript	contributed lab space and assisted in writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5591509	28886704	HRP	2	contributed resources and knowledge in chiapas and assisted in writing the manuscript	contributed resources and knowledge in chiapas and assisted in writing the manuscript	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Original Draft	YES
5591509	28886704	KLM	2	contributed funds and resources and wrote the manuscript	contributed funds and resources and wrote the manuscript	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Original Draft	YES
5591509	28886704	MAK	2	designed research, performed research, analyzed data, and wrote the manuscript	designed research, performed research, analyzed data, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5591509	28886704	SW	2	helped analyze data and assisted in writing the manuscript	helped analyze data and assisted in writing the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5715403	29250084	AS	PLoS52	carried out experimental work	carried out experimental work	Performed the experiments	Investigation	YES
5715403	29250084	CE-E	PLoS52	carried out experimental work|carried out experimental design and data analysis|wrote the paper	carried out experimental work	Performed the experiments	Investigation	YES
5715403	29250084	CE-E	PLoS52	carried out experimental work|carried out experimental design and data analysis|wrote the paper	carried out experimental design and data analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5715403	29250084	CE-E	PLoS52	carried out experimental work|carried out experimental design and data analysis|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5715403	29250084	EJ-V	PLoS52	carried out experimental work|carried out experimental design and data analysis	carried out experimental work	Performed the experiments	Investigation	YES
5715403	29250084	EJ-V	PLoS52	carried out experimental work|carried out experimental design and data analysis	carried out experimental design and data analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5715403	29250084	LR	PLoS52	carried out experimental design and data analysis|wrote the paper	carried out experimental design and data analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5715403	29250084	LR	PLoS52	carried out experimental design and data analysis|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5715403	29250084	SA	PLoS52	carried out experimental work|carried out experimental design and data analysis	carried out experimental work	Performed the experiments	Investigation	YES
5715403	29250084	SA	PLoS52	carried out experimental work|carried out experimental design and data analysis	carried out experimental design and data analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5715403	29250084	SB	PLoS52	carried out experimental design and data analysis|wrote the paper	carried out experimental design and data analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5715403	29250084	SB	PLoS52	carried out experimental design and data analysis|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5981153	29855728	AB	2	performed the readouts	performed the readouts	Performed the experiments	Investigation	YES
5981153	29855728	EEGWtV	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5981153	29855728	FdGB	2	performed the readouts	performed the readouts	Performed the experiments	Investigation	YES
5981153	29855728	HWN	2	performed the readouts	performed the readouts	Performed the experiments	Investigation	YES
5981153	29855728	IAB	2	performed the readouts|revised the manuscript	performed the readouts	Performed the experiments	Investigation	YES
5981153	29855728	IAB	2	performed the readouts|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5981153	29855728	JM	2	performed the readouts	performed the readouts	Performed the experiments	Investigation	YES
5981153	29855728	KNV	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5981153	29855728	MR	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5981153	29855728	PV	2	participated in the study coordination	participated in the study coordination	-	Project administration	YES
3844502	23967897	HJ	2	performed data specimen analysis	performed data specimen analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3844502	23967897	JMC	2	was the primary investigator, designed the study, obtained grant funds, supervised subject recruitment, data acquisition, data specimen collection, and manuscript preparation|was primarily responsible for writing the manuscript	was the primary investigator, designed the study, obtained grant funds, supervised subject recruitment, data acquisition, data specimen collection, and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Funding acquisition|Investigation|Methodology|Supervision|Writing - Original Draft	YES
3844502	23967897	JMC	2	was the primary investigator, designed the study, obtained grant funds, supervised subject recruitment, data acquisition, data specimen collection, and manuscript preparation|was primarily responsible for writing the manuscript	was primarily responsible for writing the manuscript	Wrote the paper	Writing - Original Draft	YES
3844502	23967897	MWR	2	performed data specimen analysis	performed data specimen analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3844502	23967897	RG	2	performed data specimen analysis	performed data specimen analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3844502	23967897	RW	2	made substantial contributions to manuscript writing and preparation	made substantial contributions to manuscript writing and preparation	Wrote the paper	Writing - Original Draft	YES
3844502	23967897	SASC	2	made substantial contributions to manuscript writing and preparation	made substantial contributions to manuscript writing and preparation	Wrote the paper	Writing - Original Draft	YES
3844502	23967897	TM	2	made substantial contributions to manuscript writing and preparation	made substantial contributions to manuscript writing and preparation	Wrote the paper	Writing - Original Draft	YES
3844502	23967897	VP	2	made substantial contributions to manuscript writing and preparation	made substantial contributions to manuscript writing and preparation	Wrote the paper	Writing - Original Draft	YES
4609342	26504783	David Duchesneau	2	contributed equally to this work	contributed equally to this work	-	-	NO
4609342	26504783	Jean-Michel Bourget	2	contributed equally to this work	contributed equally to this work	-	-	NO
4609342	26504783	Robert Gauvin	2	contributed equally to this work	contributed equally to this work	-	-	NO
4816958	27033544	AV	2	participated in the purification of petroselinic acid	participated in the purification of petroselinic acid	Performed the experiments	Investigation	YES
4816958	27033544	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4816958	27033544	CVS	2	contributed in coordination, generation of the grant money and manuscript revision	contributed in coordination, generation of the grant money and manuscript revision	Wrote the paper	Project administration|Writing - Review & Editing	YES
4816958	27033544	EIPD	2	participated in the purification of petroselinic acid|participated in the chemical modification of the petroselinic acid based sophorolipids|performed the surface tension measurements and drafted the manuscript	participated in the purification of petroselinic acid	Performed the experiments	Investigation	YES
4816958	27033544	EIPD	2	participated in the purification of petroselinic acid|participated in the chemical modification of the petroselinic acid based sophorolipids|performed the surface tension measurements and drafted the manuscript	participated in the chemical modification of the petroselinic acid based sophorolipids	Performed the experiments	Investigation	YES
4816958	27033544	EIPD	2	participated in the purification of petroselinic acid|participated in the chemical modification of the petroselinic acid based sophorolipids|performed the surface tension measurements and drafted the manuscript	performed the surface tension measurements and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4816958	27033544	EU	2	determined the fatty acid composition of the coriander oil|participated in the purification of petroselinic acid	determined the fatty acid composition of the coriander oil	-	-	NO
4816958	27033544	EU	2	determined the fatty acid composition of the coriander oil|participated in the purification of petroselinic acid	participated in the purification of petroselinic acid	Performed the experiments	Investigation	YES
4816958	27033544	INAVB	2	contributed in coordination, generation of the grant money and manuscript revision	contributed in coordination, generation of the grant money and manuscript revision	Wrote the paper	Project administration|Writing - Review & Editing	YES
4816958	27033544	JE	2	participated in the purification of petroselinic acid|carried out the sophorolipid fermentation|participated in the chemical modification of the petroselinic acid based sophorolipids	participated in the purification of petroselinic acid	Performed the experiments	Investigation	YES
4816958	27033544	JE	2	participated in the purification of petroselinic acid|carried out the sophorolipid fermentation|participated in the chemical modification of the petroselinic acid based sophorolipids	carried out the sophorolipid fermentation	Performed the experiments	Investigation	YES
4816958	27033544	JE	2	participated in the purification of petroselinic acid|carried out the sophorolipid fermentation|participated in the chemical modification of the petroselinic acid based sophorolipids	participated in the chemical modification of the petroselinic acid based sophorolipids	Performed the experiments	Investigation	YES
4816958	27033544	SV	2	carried out the sophorolipid fermentation	carried out the sophorolipid fermentation	Performed the experiments	Investigation	YES
4816958	27033544	TT	2	contributed in coordination, generation of the grant money and manuscript revision	contributed in coordination, generation of the grant money and manuscript revision	Wrote the paper	Project administration|Writing - Review & Editing	YES
4816958	27033544	WS	2	contributed in coordination, generation of the grant money and manuscript revision	contributed in coordination, generation of the grant money and manuscript revision	Wrote the paper	Project administration|Writing - Review & Editing	YES
1891085	17579716	EB	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1891085	17579716	EN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1891085	17579716	EN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1891085	17579716	EN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1891085	17579716	EN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1891085	17579716	HF	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1891085	17579716	HF	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1891085	17579716	JD	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1891085	17579716	JV	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1891085	17579716	JV	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1891085	17579716	SG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1891085	17579716	SG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1891085	17579716	SG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1891085	17579716	SG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1891085	17579716	SG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1891085	17579716	TK	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1891085	17579716	YS	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4414470	25923541	ARG	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414470	25923541	ARG	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414470	25923541	CWA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414470	25923541	CWA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414470	25923541	CWA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414470	25923541	JMO	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414470	25923541	JMO	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414470	25923541	MC-A	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414470	25923541	MC-A	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414470	25923541	MTM	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414470	25923541	PB	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4414470	25923541	SJG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414470	25923541	SJG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414470	25923541	SJG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414470	25923541	SJG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5981157	29855729	ES	2	were the supervisors of the study	were the supervisors of the study	-	Supervision	YES
5981157	29855729	HI	2	performed the radiosynthesis	performed the radiosynthesis	Performed the experiments	Investigation	YES
5981157	29855729	HK	2	performed the histological study and assessment, western blotting, and qrt pcr	performed the histological study and assessment, western blotting, and qrt pcr	Performed the experiments	Investigation	YES
5981157	29855729	JH	2	were the supervisors of the study	were the supervisors of the study	-	Supervision	YES
5981157	29855729	KA	2	participated in the study coordination and the design of the study and drafted the manuscript	participated in the study coordination and the design of the study and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft	YES
5981157	29855729	MI	2	performed the pet experiments	performed the pet experiments	Performed the experiments	Investigation	YES
5981157	29855729	RN	2	performed the histological assessment and drafted the manuscript	performed the histological assessment and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5981157	29855729	TR	2	participated in the design of the study, performed and analyzed the pet experiments, statistics analyses, and drafted the manuscript	participated in the design of the study, performed and analyzed the pet experiments, statistics analyses, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5715477	29250098	AC	2	reconstructed the model|carried out simulation and analysis|wrote the manuscript	reconstructed the model	Performed the experiments	Investigation|Methodology	YES
5715477	29250098	AC	2	reconstructed the model|carried out simulation and analysis|wrote the manuscript	carried out simulation and analysis	Performed the experiments	Formal analysis|Investigation	YES
5715477	29250098	AC	2	reconstructed the model|carried out simulation and analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5715477	29250098	BH	2	reconstructed the model|carried out simulation and analysis|wrote the manuscript	reconstructed the model	Performed the experiments	Investigation|Methodology	YES
5715477	29250098	BH	2	reconstructed the model|carried out simulation and analysis|wrote the manuscript	carried out simulation and analysis	Performed the experiments	Formal analysis|Investigation	YES
5715477	29250098	BH	2	reconstructed the model|carried out simulation and analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5715477	29250098	RS	2	carried out simulation and analysis	carried out simulation and analysis	Performed the experiments	Formal analysis|Investigation	YES
5715477	29250098	SK	2	supervised the work	supervised the work	-	Supervision	YES
3848455	24034227	BCR	2	participated in conception, design, and data acquisition, assisted in analysis and interpretation of data, and aided in the drafting and revising of the manuscript	participated in conception, design, and data acquisition, assisted in analysis and interpretation of data, and aided in the drafting and revising of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
3848455	24034227	CLD	2	participated in conception, design, and data acquisition, assisted in pcr analysis and interpretation of data, and wrote the manuscript	participated in conception, design, and data acquisition, assisted in pcr analysis and interpretation of data, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
3848455	24034227	DRS	2	participated in conception, design, and data acquisition, assisted in pcr analysis and interpretation of data, and aided in the drafting and revising of the manuscript	participated in conception, design, and data acquisition, assisted in pcr analysis and interpretation of data, and aided in the drafting and revising of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
3848455	24034227	JSC	2	participated in data acquisition, analysis and interpretation of data, and aided in the drafting and revising of the manuscript	participated in data acquisition, analysis and interpretation of data, and aided in the drafting and revising of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
3848455	24034227	WSH	2	participated in data acquisition, analysis and interpretation of data, and aided in the drafting and revising of the manuscript	participated in data acquisition, analysis and interpretation of data, and aided in the drafting and revising of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
4609343	26504777	Albuquerque Luna	PLoS52	conceived and designed the experiments|contributed with reagents/material/analysis tools	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4609343	26504777	Albuquerque Luna	PLoS52	conceived and designed the experiments|contributed with reagents/material/analysis tools	contributed with reagents/material/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4609343	26504777	Elenice Messias	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
4609343	26504777	Emmanuel Dias-Neto	PLoS52	performed the experiments|contributed with reagents/material/analysis tools	performed the experiments	Performed the experiments	Investigation	YES
4609343	26504777	Emmanuel Dias-Neto	PLoS52	performed the experiments|contributed with reagents/material/analysis tools	contributed with reagents/material/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4609343	26504777	Expedito Jose	PLoS52	conceived and designed the experiments|contributed with reagents/material/analysis tools	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4609343	26504777	Expedito Jose	PLoS52	conceived and designed the experiments|contributed with reagents/material/analysis tools	contributed with reagents/material/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4609343	26504777	Flair Jose Carrilho	PLoS52	contributed with reagents/material/analysis tools	contributed with reagents/material/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4609343	26504777	Joao Renato Rebello	PLoS52	performed the experiments|contributed with reagents/material/analysis tools	performed the experiments	Performed the experiments	Investigation	YES
4609343	26504777	Joao Renato Rebello	PLoS52	performed the experiments|contributed with reagents/material/analysis tools	contributed with reagents/material/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4609343	26504777	Maria Carmen Arroyo	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
4609343	26504777	Maria Cristina Carvalho	PLoS52	contributed with reagents/material/analysis tools	contributed with reagents/material/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4609343	26504777	Nascimento Goncalves	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
4609343	26504777	Pedro Luiz Silva	PLoS52	conceived and designed the experiments|performed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4609343	26504777	Pedro Luiz Silva	PLoS52	conceived and designed the experiments|performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
4609343	26504777	Ronaldo Cesar Borges	PLoS52	conceived and designed the experiments|contributed with reagents/material/analysis tools	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4609343	26504777	Ronaldo Cesar Borges	PLoS52	conceived and designed the experiments|contributed with reagents/material/analysis tools	contributed with reagents/material/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4609343	26504777	Vera Lucia Pagliusi	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
4609343	26504777	Viviana Alvarado-Mora	PLoS52	conceived and designed the experiments|performed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4609343	26504777	Viviana Alvarado-Mora	PLoS52	conceived and designed the experiments|performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
1891086	17579720	CH	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1891086	17579720	CH	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1891086	17579720	JB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1891086	17579720	JB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1891086	17579720	JB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1891086	17579720	JK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1891086	17579720	JK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1891086	17579720	JK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1891086	17579720	JS	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Analyzed the data|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Wrote the paper|Wrote the paper|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1891086	17579720	JS	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Analyzed the data|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Wrote the paper|Wrote the paper|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1891086	17579720	JS	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Analyzed the data|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Wrote the paper|Wrote the paper|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1891086	17579720	JS	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Analyzed the data|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Wrote the paper|Wrote the paper|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1891086	17579720	JS	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Analyzed the data|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Wrote the paper|Wrote the paper|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1891086	17579720	JS	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Analyzed the data|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Wrote the paper|Wrote the paper|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1891086	17579720	JS	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Analyzed the data|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Wrote the paper|Wrote the paper|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1891086	17579720	JS	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Analyzed the data|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Wrote the paper|Wrote the paper|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1891086	17579720	JS	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Analyzed the data|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Wrote the paper|Wrote the paper|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1891086	17579720	JS	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Analyzed the data|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Wrote the paper|Wrote the paper|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1891086	17579720	QL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1891086	17579720	QL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1891086	17579720	QL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1891086	17579720	YL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1891086	17579720	YL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1891086	17579720	YL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1891086	17579720	YL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1891086	17579720	YL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1891086	17579720	ZL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1891086	17579720	ZL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1891086	17579720	ZL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1891086	17579720	ZL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1891086	17579720	ZL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3849504	24066848	APH	2	secured support for this study and helped with manuscript writing	secured support for this study and helped with manuscript writing	Wrote the paper	Writing - Original Draft	YES
3849504	24066848	JB	2	helped with manuscript writing	helped with manuscript writing	Wrote the paper	Writing - Original Draft	YES
3849504	24066848	SCL	2	defined the design of the study, undertook data collection, data collation, data analysis and manuscript preparation	defined the design of the study, undertook data collection, data collation, data analysis and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4414471	25923669	DPL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414471	25923669	DYL	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4414471	25923669	RJS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414471	25923669	TJ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414471	25923669	XGZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414471	25923669	XGZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414471	25923669	XGZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414471	25923669	XGZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414471	25923669	XLP	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414471	25923669	XYY	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5992109	29881881	AB	2	contributed to the study concepts|contributed to the study design|contributed to the data acquisition|contributed to the quality control of data|contributed to the data analyses and interpretation|contributed to the statistical analysis|contributed to the manuscript preparation|contributed to the manuscript editing|contributed to the manuscript review	contributed to the study concepts	Conceived and designed the experiments	Conceptualization	YES
5992109	29881881	AB	2	contributed to the study concepts|contributed to the study design|contributed to the data acquisition|contributed to the quality control of data|contributed to the data analyses and interpretation|contributed to the statistical analysis|contributed to the manuscript preparation|contributed to the manuscript editing|contributed to the manuscript review	contributed to the study design	Conceived and designed the experiments	Methodology	YES
5992109	29881881	AB	2	contributed to the study concepts|contributed to the study design|contributed to the data acquisition|contributed to the quality control of data|contributed to the data analyses and interpretation|contributed to the statistical analysis|contributed to the manuscript preparation|contributed to the manuscript editing|contributed to the manuscript review	contributed to the data acquisition	Performed the experiments	Investigation	YES
5992109	29881881	AB	2	contributed to the study concepts|contributed to the study design|contributed to the data acquisition|contributed to the quality control of data|contributed to the data analyses and interpretation|contributed to the statistical analysis|contributed to the manuscript preparation|contributed to the manuscript editing|contributed to the manuscript review	contributed to the quality control of data	Performed the experiments|Contributed reagents/materials/analysis tools	Resources|Validation	YES
5992109	29881881	AB	2	contributed to the study concepts|contributed to the study design|contributed to the data acquisition|contributed to the quality control of data|contributed to the data analyses and interpretation|contributed to the statistical analysis|contributed to the manuscript preparation|contributed to the manuscript editing|contributed to the manuscript review	contributed to the data analyses and interpretation	Analyzed the data	Formal analysis	YES
5992109	29881881	AB	2	contributed to the study concepts|contributed to the study design|contributed to the data acquisition|contributed to the quality control of data|contributed to the data analyses and interpretation|contributed to the statistical analysis|contributed to the manuscript preparation|contributed to the manuscript editing|contributed to the manuscript review	contributed to the statistical analysis	Analyzed the data	Formal analysis	YES
5992109	29881881	AB	2	contributed to the study concepts|contributed to the study design|contributed to the data acquisition|contributed to the quality control of data|contributed to the data analyses and interpretation|contributed to the statistical analysis|contributed to the manuscript preparation|contributed to the manuscript editing|contributed to the manuscript review	contributed to the manuscript preparation	Wrote the paper	Writing - Original Draft	YES
5992109	29881881	AB	2	contributed to the study concepts|contributed to the study design|contributed to the data acquisition|contributed to the quality control of data|contributed to the data analyses and interpretation|contributed to the statistical analysis|contributed to the manuscript preparation|contributed to the manuscript editing|contributed to the manuscript review	contributed to the manuscript editing	Wrote the paper	Writing - Review & Editing	YES
5992109	29881881	AB	2	contributed to the study concepts|contributed to the study design|contributed to the data acquisition|contributed to the quality control of data|contributed to the data analyses and interpretation|contributed to the statistical analysis|contributed to the manuscript preparation|contributed to the manuscript editing|contributed to the manuscript review	contributed to the manuscript review	Wrote the paper	Writing - Review & Editing	YES
5992109	29881881	AS	2	contributed to the data acquisition|contributed to the quality control of data|contributed to the manuscript editing|contributed to the manuscript review	contributed to the data acquisition	Performed the experiments	Investigation	YES
5992109	29881881	AS	2	contributed to the data acquisition|contributed to the quality control of data|contributed to the manuscript editing|contributed to the manuscript review	contributed to the quality control of data	Performed the experiments|Contributed reagents/materials/analysis tools	Resources|Validation	YES
5992109	29881881	AS	2	contributed to the data acquisition|contributed to the quality control of data|contributed to the manuscript editing|contributed to the manuscript review	contributed to the manuscript editing	Wrote the paper	Writing - Review & Editing	YES
5992109	29881881	AS	2	contributed to the data acquisition|contributed to the quality control of data|contributed to the manuscript editing|contributed to the manuscript review	contributed to the manuscript review	Wrote the paper	Writing - Review & Editing	YES
5992109	29881881	HH	2	contributed to the study concepts|contributed to the study design|contributed to the manuscript editing|contributed to the manuscript review	contributed to the study concepts	Conceived and designed the experiments	Conceptualization	YES
5992109	29881881	HH	2	contributed to the study concepts|contributed to the study design|contributed to the manuscript editing|contributed to the manuscript review	contributed to the study design	Conceived and designed the experiments	Methodology	YES
5992109	29881881	HH	2	contributed to the study concepts|contributed to the study design|contributed to the manuscript editing|contributed to the manuscript review	contributed to the manuscript editing	Wrote the paper	Writing - Review & Editing	YES
5992109	29881881	HH	2	contributed to the study concepts|contributed to the study design|contributed to the manuscript editing|contributed to the manuscript review	contributed to the manuscript review	Wrote the paper	Writing - Review & Editing	YES
5992109	29881881	LB	2	contributed to the study concepts|contributed to the study design|contributed to the manuscript preparation|contributed to the manuscript editing|contributed to the manuscript review	contributed to the study concepts	Conceived and designed the experiments	Conceptualization	YES
5992109	29881881	LB	2	contributed to the study concepts|contributed to the study design|contributed to the manuscript preparation|contributed to the manuscript editing|contributed to the manuscript review	contributed to the study design	Conceived and designed the experiments	Methodology	YES
5992109	29881881	LB	2	contributed to the study concepts|contributed to the study design|contributed to the manuscript preparation|contributed to the manuscript editing|contributed to the manuscript review	contributed to the manuscript preparation	Wrote the paper	Writing - Original Draft	YES
5992109	29881881	LB	2	contributed to the study concepts|contributed to the study design|contributed to the manuscript preparation|contributed to the manuscript editing|contributed to the manuscript review	contributed to the manuscript editing	Wrote the paper	Writing - Review & Editing	YES
5992109	29881881	LB	2	contributed to the study concepts|contributed to the study design|contributed to the manuscript preparation|contributed to the manuscript editing|contributed to the manuscript review	contributed to the manuscript review	Wrote the paper	Writing - Review & Editing	YES
5992109	29881881	MS	2	contributed to the study concepts|contributed to the study design|contributed to the data acquisition|contributed to the quality control of data|contributed to the data analyses and interpretation|contributed to the statistical analysis|contributed to the manuscript preparation|contributed to the manuscript editing|contributed to the manuscript review	contributed to the study concepts	Conceived and designed the experiments	Conceptualization	YES
5992109	29881881	MS	2	contributed to the study concepts|contributed to the study design|contributed to the data acquisition|contributed to the quality control of data|contributed to the data analyses and interpretation|contributed to the statistical analysis|contributed to the manuscript preparation|contributed to the manuscript editing|contributed to the manuscript review	contributed to the study design	Conceived and designed the experiments	Methodology	YES
5992109	29881881	MS	2	contributed to the study concepts|contributed to the study design|contributed to the data acquisition|contributed to the quality control of data|contributed to the data analyses and interpretation|contributed to the statistical analysis|contributed to the manuscript preparation|contributed to the manuscript editing|contributed to the manuscript review	contributed to the data acquisition	Performed the experiments	Investigation	YES
5992109	29881881	MS	2	contributed to the study concepts|contributed to the study design|contributed to the data acquisition|contributed to the quality control of data|contributed to the data analyses and interpretation|contributed to the statistical analysis|contributed to the manuscript preparation|contributed to the manuscript editing|contributed to the manuscript review	contributed to the quality control of data	Performed the experiments|Contributed reagents/materials/analysis tools	Resources|Validation	YES
5992109	29881881	MS	2	contributed to the study concepts|contributed to the study design|contributed to the data acquisition|contributed to the quality control of data|contributed to the data analyses and interpretation|contributed to the statistical analysis|contributed to the manuscript preparation|contributed to the manuscript editing|contributed to the manuscript review	contributed to the data analyses and interpretation	Analyzed the data	Formal analysis	YES
5992109	29881881	MS	2	contributed to the study concepts|contributed to the study design|contributed to the data acquisition|contributed to the quality control of data|contributed to the data analyses and interpretation|contributed to the statistical analysis|contributed to the manuscript preparation|contributed to the manuscript editing|contributed to the manuscript review	contributed to the statistical analysis	Analyzed the data	Formal analysis	YES
5992109	29881881	MS	2	contributed to the study concepts|contributed to the study design|contributed to the data acquisition|contributed to the quality control of data|contributed to the data analyses and interpretation|contributed to the statistical analysis|contributed to the manuscript preparation|contributed to the manuscript editing|contributed to the manuscript review	contributed to the manuscript preparation	Wrote the paper	Writing - Original Draft	YES
5992109	29881881	MS	2	contributed to the study concepts|contributed to the study design|contributed to the data acquisition|contributed to the quality control of data|contributed to the data analyses and interpretation|contributed to the statistical analysis|contributed to the manuscript preparation|contributed to the manuscript editing|contributed to the manuscript review	contributed to the manuscript editing	Wrote the paper	Writing - Review & Editing	YES
5992109	29881881	MS	2	contributed to the study concepts|contributed to the study design|contributed to the data acquisition|contributed to the quality control of data|contributed to the data analyses and interpretation|contributed to the statistical analysis|contributed to the manuscript preparation|contributed to the manuscript editing|contributed to the manuscript review	contributed to the manuscript review	Wrote the paper	Writing - Review & Editing	YES
5992109	29881881	RB	2	contributed to the study concepts|contributed to the study design|contributed to the data acquisition|contributed to the quality control of data|contributed to the data analyses and interpretation|contributed to the statistical analysis|contributed to the manuscript preparation|contributed to the manuscript editing|contributed to the manuscript review	contributed to the study concepts	Conceived and designed the experiments	Conceptualization	YES
5992109	29881881	RB	2	contributed to the study concepts|contributed to the study design|contributed to the data acquisition|contributed to the quality control of data|contributed to the data analyses and interpretation|contributed to the statistical analysis|contributed to the manuscript preparation|contributed to the manuscript editing|contributed to the manuscript review	contributed to the study design	Conceived and designed the experiments	Methodology	YES
5992109	29881881	RB	2	contributed to the study concepts|contributed to the study design|contributed to the data acquisition|contributed to the quality control of data|contributed to the data analyses and interpretation|contributed to the statistical analysis|contributed to the manuscript preparation|contributed to the manuscript editing|contributed to the manuscript review	contributed to the data acquisition	Performed the experiments	Investigation	YES
5992109	29881881	RB	2	contributed to the study concepts|contributed to the study design|contributed to the data acquisition|contributed to the quality control of data|contributed to the data analyses and interpretation|contributed to the statistical analysis|contributed to the manuscript preparation|contributed to the manuscript editing|contributed to the manuscript review	contributed to the quality control of data	Performed the experiments|Contributed reagents/materials/analysis tools	Resources|Validation	YES
5992109	29881881	RB	2	contributed to the study concepts|contributed to the study design|contributed to the data acquisition|contributed to the quality control of data|contributed to the data analyses and interpretation|contributed to the statistical analysis|contributed to the manuscript preparation|contributed to the manuscript editing|contributed to the manuscript review	contributed to the data analyses and interpretation	Analyzed the data	Formal analysis	YES
5992109	29881881	RB	2	contributed to the study concepts|contributed to the study design|contributed to the data acquisition|contributed to the quality control of data|contributed to the data analyses and interpretation|contributed to the statistical analysis|contributed to the manuscript preparation|contributed to the manuscript editing|contributed to the manuscript review	contributed to the statistical analysis	Analyzed the data	Formal analysis	YES
5992109	29881881	RB	2	contributed to the study concepts|contributed to the study design|contributed to the data acquisition|contributed to the quality control of data|contributed to the data analyses and interpretation|contributed to the statistical analysis|contributed to the manuscript preparation|contributed to the manuscript editing|contributed to the manuscript review	contributed to the manuscript preparation	Wrote the paper	Writing - Original Draft	YES
5992109	29881881	RB	2	contributed to the study concepts|contributed to the study design|contributed to the data acquisition|contributed to the quality control of data|contributed to the data analyses and interpretation|contributed to the statistical analysis|contributed to the manuscript preparation|contributed to the manuscript editing|contributed to the manuscript review	contributed to the manuscript editing	Wrote the paper	Writing - Review & Editing	YES
5992109	29881881	RB	2	contributed to the study concepts|contributed to the study design|contributed to the data acquisition|contributed to the quality control of data|contributed to the data analyses and interpretation|contributed to the statistical analysis|contributed to the manuscript preparation|contributed to the manuscript editing|contributed to the manuscript review	contributed to the manuscript review	Wrote the paper	Writing - Review & Editing	YES
5716317	29250080	AK	PLoS52	aligned dartseq data with the reference genomes	aligned dartseq data with the reference genomes	-	-	NO
5716317	29250080	All authors	PLoS52	reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5716317	29250080	HR	PLoS52	designed the study, and prepared the manuscript	designed the study, and prepared the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5716317	29250080	JS	PLoS52	aligned dartseq data with the reference genomes	aligned dartseq data with the reference genomes	-	-	NO
5716317	29250080	NC	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5716317	29250080	RR	PLoS52	designed the study, and prepared the manuscript|analyzed the data	designed the study, and prepared the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5716317	29250080	RR	PLoS52	designed the study, and prepared the manuscript|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5716317	29250080	YQ	PLoS52	assisted in phenotyping, performed pod anatomy, and dna extractions	assisted in phenotyping, performed pod anatomy, and dna extractions	Performed the experiments	Investigation	YES
5591513	28886690	ACS	2	took part in manuscript writing	took part in manuscript writing	Wrote the paper	Writing - Original Draft	YES
5591513	28886690	CCP	2	assisted with fatty acid analyses, statistical analyses and data interpretation	assisted with fatty acid analyses, statistical analyses and data interpretation	Analyzed the data	Formal analysis	YES
5591513	28886690	JRH	2	performed and analysed the experimental qpcr studies	performed and analysed the experimental qpcr studies	Performed the experiments	Investigation	YES
5591513	28886690	KE	2	took a lead role in experimental design, assay development, cell isolation and sampling, microarray design and analyses, qpcr assay development, data analyses, data interpretation and the writing of this manuscript	took a lead role in experimental design, assay development, cell isolation and sampling, microarray design and analyses, qpcr assay development, data analyses, data interpretation and the writing of this manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5591513	28886690	MLR	2	was involved in experimental design, microarray experiment design, data analyses, and data interpretation, and he took an active role in manuscript writing	was involved in experimental design, microarray experiment design, data analyses, and data interpretation, and he took an active role in manuscript writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5591513	28886690	NCS	2	carried out phagocytosis and rb assays and helped with writing a part of the manuscript	carried out phagocytosis and rb assays and helped with writing a part of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5591513	28886690	RGT	2	designed and formulated the experimental diets	designed and formulated the experimental diets	Conceived and designed the experiments	Conceptualization|Methodology	YES
5591513	28886690	XX	2	helped with microarray experiment design and analyses as well as data interpretation	helped with microarray experiment design and analyses as well as data interpretation	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
1891087	17579721	MA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1891087	17579721	MA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1891087	17579721	MA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1891087	17579721	MA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1891087	17579721	MA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1891087	17579721	MD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1891087	17579721	MD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1891087	17579721	MD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1891087	17579721	MD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1891087	17579721	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1891087	17579721	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1891087	17579721	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1891087	17579721	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1891087	17579721	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1891087	17579721	PF	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1891087	17579721	PF	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1891087	17579721	PF	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1891087	17579721	XJ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1891087	17579721	XJ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1891087	17579721	XJ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1891087	17579721	YC	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1891087	17579721	YC	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1891087	17579721	YC	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1891087	17579721	YZ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1891087	17579721	YZ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1891087	17579721	YZ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1891087	17579721	ZR	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1891087	17579721	ZR	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1891087	17579721	ZV	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
3850644	24066806	DCS	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3850644	24066806	VCF	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4414473	25923106	BF	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414473	25923106	MJB	PLoS5	Conceived and designed the experiments|Wrote the paper|Obtained permission to use data for this analysis	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414473	25923106	MJB	PLoS5	Conceived and designed the experiments|Wrote the paper|Obtained permission to use data for this analysis	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414473	25923106	MJB	PLoS5	Conceived and designed the experiments|Wrote the paper|Obtained permission to use data for this analysis	Obtained permission to use data for this analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4414473	25923106	MWF	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414473	25923106	MWF	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414473	25923106	SMM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414473	25923106	SMM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414473	25923106	SMM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3851572	24107586	EOS	2	was involved in concept and design, analysis of data, and manuscript preparation	was involved in concept and design, analysis of data, and manuscript preparation	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
3851572	24107586	JED	2	contributed in concept and design, data acquisition, analysis of data, and manuscript preparation	contributed in concept and design, data acquisition, analysis of data, and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Resources|Writing - Original Draft	YES
3851572	24107586	JMJ	2	contributed in concept and design, data acquisition, analysis of data, and manuscript preparation	contributed in concept and design, data acquisition, analysis of data, and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Resources|Writing - Original Draft	YES
3851572	24107586	JMW	2	contributed in concept and design, data acquisition, analysis of data, and manuscript preparation	contributed in concept and design, data acquisition, analysis of data, and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Resources|Writing - Original Draft	YES
3851572	24107586	RPL	2	contributed in concept and design, data acquisition, analysis of data, and manuscript preparation	contributed in concept and design, data acquisition, analysis of data, and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Resources|Writing - Original Draft	YES
3851572	24107586	RW	2	were involved in concept and design and manuscript preparation	were involved in concept and design and manuscript preparation	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
3851572	24107586	SAM	2	contributed in concept and design, data acquisition, analysis of data, and manuscript preparation	contributed in concept and design, data acquisition, analysis of data, and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Resources|Writing - Original Draft	YES
3851572	24107586	SW	2	were involved in concept and design and manuscript preparation	were involved in concept and design and manuscript preparation	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
1891088	17579727	LC	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1891088	17579727	LC	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1891088	17579727	NR	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1891088	17579727	NR	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5717384	29250097	All authors	2	offered revisions and approved the final manuscript	offered revisions and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
3752286	23984265	CG	2	provided statistical analysis	provided statistical analysis	Analyzed the data	Formal analysis	YES
3752286	23984265	CS	2	participated in study design, coordination, data collection and analysis	participated in study design, coordination, data collection and analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology|Project administration	YES
3752286	23984265	JS	2	participated in study design, data collection and analysis, and was responsible for manuscript drafting	participated in study design, data collection and analysis, and was responsible for manuscript drafting	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
3752286	23984265	LD	2	participated in data collection|provided cultural advice and language translation	participated in data collection	Performed the experiments	Investigation	YES
3752286	23984265	LD	2	participated in data collection|provided cultural advice and language translation	provided cultural advice and language translation	-	-	NO
3752286	23984265	LL	2	was responsible for study conception, design and coordination, and participated in data collection, analysis and manuscript preparation	was responsible for study conception, design and coordination, and participated in data collection, analysis and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Project administration|Writing - Original Draft	YES
3752286	23984265	MS	2	participated in study design, coordination, data collection and analysis	participated in study design, coordination, data collection and analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology|Project administration	YES
3752286	23984265	PN	2	participated in the conception of the study and data interpretation	participated in the conception of the study and data interpretation	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
3752286	23984265	PO	2	participated in conception of the study, study design, data collection and analysis and manuscript preparation	participated in conception of the study, study design, data collection and analysis and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4840137	27103628	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4840137	27103628	Jorge Ferreira	2	for their technical assistance and valuable discussions	for their technical assistance and valuable discussions	Performed the experiments	Investigation	YES
4840137	27103628	Marlen Kilberg	2	for their technical assistance and valuable discussions	for their technical assistance and valuable discussions	Performed the experiments	Investigation	YES
4840137	27103628	Mostafa Jabbari	2	for their technical assistance and valuable discussions	for their technical assistance and valuable discussions	Performed the experiments	Investigation	YES
4414474	25923206	BLE	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414474	25923206	BLE	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414474	25923206	BLE	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414474	25923206	BLE	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414474	25923206	KCB	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414474	25923206	KCB	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414474	25923206	MGC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414474	25923206	MGC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414474	25923206	MGC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414474	25923206	SSJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414474	25923206	SSJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414474	25923206	SSJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414474	25923206	SSJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414474	25923206	SSJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3853711	24144232	HS	2	were responsible for the concept of this project and for the study design	were responsible for the concept of this project and for the study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
3853711	24144232	IP	2	were responsible for the concept of this project and for the study design	were responsible for the concept of this project and for the study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
3853711	24144232	KVP	2	were responsible for the acquisition and the analysis of the data|were responsible for the interpretation of the data	were responsible for the acquisition and the analysis of the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3853711	24144232	KVP	2	were responsible for the acquisition and the analysis of the data|were responsible for the interpretation of the data	were responsible for the interpretation of the data	Analyzed the data	Formal analysis	YES
3853711	24144232	LD	2	were responsible for the interpretation of the data|wrote the first version of the manuscript which was edited by the other authors	were responsible for the interpretation of the data	Analyzed the data	Formal analysis	YES
3853711	24144232	LD	2	were responsible for the interpretation of the data|wrote the first version of the manuscript which was edited by the other authors	wrote the first version of the manuscript which was edited by the other authors	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3853711	24144232	MR	2	were responsible for the acquisition and the analysis of the data	were responsible for the acquisition and the analysis of the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3853711	24144232	PH	2	were responsible for the concept of this project and for the study design|were responsible for the interpretation of the data|wrote the first version of the manuscript which was edited by the other authors	were responsible for the concept of this project and for the study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
3853711	24144232	PH	2	were responsible for the concept of this project and for the study design|were responsible for the interpretation of the data|wrote the first version of the manuscript which was edited by the other authors	were responsible for the interpretation of the data	Analyzed the data	Formal analysis	YES
3853711	24144232	PH	2	were responsible for the concept of this project and for the study design|were responsible for the interpretation of the data|wrote the first version of the manuscript which was edited by the other authors	wrote the first version of the manuscript which was edited by the other authors	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5993708	29884977	ARG	2	histological and immunohistochemical study, and pet analysis	histological and immunohistochemical study, and pet analysis	Performed the experiments	Investigation	YES
5993708	29884977	ES	2	were the supervisors of the study	were the supervisors of the study	-	Supervision	YES
5993708	29884977	HI	2	performed the radioligand synthesis	performed the radioligand synthesis	Performed the experiments	Investigation	YES
5993708	29884977	JH	2	were the supervisors of the study	were the supervisors of the study	-	Supervision	YES
5993708	29884977	KA	2	participated in the study coordination and the design of the study and drafted the manuscript	participated in the study coordination and the design of the study and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft	YES
5993708	29884977	MI	2	performed the mcao operation and pet experiments	performed the mcao operation and pet experiments	Performed the experiments	Investigation	YES
5993708	29884977	NM	2	participated in the design of the study	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
5993708	29884977	SM	2	performed the pet analysis and drafted the manuscript	performed the pet analysis and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5993708	29884977	SO	2	performed the immunohistochemical study	performed the immunohistochemical study	Performed the experiments	Investigation	YES
5993708	29884977	TR	2	performed pet experiments	performed pet experiments	Performed the experiments	Investigation	YES
4609346	26504781	Michael Gramlich	2	contributed equally to this work	contributed equally to this work	-	-	NO
4609346	26504781	Michael P. Feneley	2	contributed equally to this work	contributed equally to this work	-	-	NO
4609346	26504781	Qifeng Zhou	2	contributed equally to this work	contributed equally to this work	-	-	NO
4609346	26504781	Richard P. Harvey	2	contributed equally to this work	contributed equally to this work	-	-	NO
4609346	26504781	Scott Kesteven	2	contributed equally to this work	contributed equally to this work	-	-	NO
1891089	17579722	AK	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1891089	17579722	AK	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1891089	17579722	AM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1891089	17579722	AM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1891089	17579722	AM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1891089	17579722	AN	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1891089	17579722	AN	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1891089	17579722	EM	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1891089	17579722	EM	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1891089	17579722	IO	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1891089	17579722	IO	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1891089	17579722	MW	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1891089	17579722	MW	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1891089	17579722	PS	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1891089	17579722	PS	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1891089	17579722	RJ	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1891089	17579722	RJ	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1891089	17579722	RR	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1891089	17579722	RR	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1891089	17579722	RV	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1891089	17579722	RV	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3874647	24330488	MAJ	7	Conception and design, analysis and interpretation of the data, drafting and critically reviewing the manuscript	Conception and design, analysis and interpretation of the data, drafting and critically reviewing the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
3874647	24330488	MSJ	7	Drafting and critically reviewing the manuscript	Drafting and critically reviewing the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3874647	24330488	SCP	7	Interpretation of the data, drafting and critically reviewing the manuscript	Interpretation of the data, drafting and critically reviewing the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
3874647	24330488	SJ	7	Conception, interpretation of the data, drafting and critically reviewing the manuscript	Conception, interpretation of the data, drafting and critically reviewing the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
3874647	24330488	UA	7	Drafting and critically reviewing the manuscript	Drafting and critically reviewing the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5723009	29255473	All authors	2	listed have made a substantial, direct and intellectual contribution to the work, and approved it for publication	listed have made a substantial, direct and intellectual contribution to the work, and approved it for publication	-	-	NO
4414476	25923207	AS	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4414476	25923207	DK	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414476	25923207	DK	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414476	25923207	DS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4414476	25923207	DS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4414476	25923207	DS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414476	25923207	GG	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414476	25923207	IM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414476	25923207	IM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414476	25923207	IM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414476	25923207	IM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414476	25923207	IM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414476	25923207	JS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4414476	25923207	JS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414476	25923207	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414476	25923207	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414476	25923207	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414476	25923207	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5591532	28886694	AYL	2	helped to collect and prepare the samples for fiber quality exam and rna sequencing	helped to collect and prepare the samples for fiber quality exam and rna sequencing	Performed the experiments	Investigation	YES
5591532	28886694	HHS	2	helped to collect and prepare the samples for fiber quality exam and rna sequencing	helped to collect and prepare the samples for fiber quality exam and rna sequencing	Performed the experiments	Investigation	YES
5591532	28886694	HR	2	helped to collect and prepare the samples for fiber quality exam and rna sequencing	helped to collect and prepare the samples for fiber quality exam and rna sequencing	Performed the experiments	Investigation	YES
5591532	28886694	JWG	2	helped to collect and prepare the samples for fiber quality exam and rna sequencing	helped to collect and prepare the samples for fiber quality exam and rna sequencing	Performed the experiments	Investigation	YES
5591532	28886694	JWL	2	helped to collect and prepare the samples for fiber quality exam and rna sequencing	helped to collect and prepare the samples for fiber quality exam and rna sequencing	Performed the experiments	Investigation	YES
5591532	28886694	LXG	2	helped to collect and prepare the samples for fiber quality exam and rna sequencing	helped to collect and prepare the samples for fiber quality exam and rna sequencing	Performed the experiments	Investigation	YES
5591532	28886694	MW	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5591532	28886694	PTL	2	conceived and designed the study|drafted the manuscript|helped to collect and prepare the samples for fiber quality exam and rna sequencing|analyzed the rna seq data	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5591532	28886694	PTL	2	conceived and designed the study|drafted the manuscript|helped to collect and prepare the samples for fiber quality exam and rna sequencing|analyzed the rna seq data	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5591532	28886694	PTL	2	conceived and designed the study|drafted the manuscript|helped to collect and prepare the samples for fiber quality exam and rna sequencing|analyzed the rna seq data	helped to collect and prepare the samples for fiber quality exam and rna sequencing	Performed the experiments	Investigation	YES
5591532	28886694	PTL	2	conceived and designed the study|drafted the manuscript|helped to collect and prepare the samples for fiber quality exam and rna sequencing|analyzed the rna seq data	analyzed the rna seq data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5591532	28886694	QG	2	helped to collect and prepare the samples for fiber quality exam and rna sequencing	helped to collect and prepare the samples for fiber quality exam and rna sequencing	Performed the experiments	Investigation	YES
5591532	28886694	QWL	2	helped to collect and prepare the samples for fiber quality exam and rna sequencing	helped to collect and prepare the samples for fiber quality exam and rna sequencing	Performed the experiments	Investigation	YES
5591532	28886694	SQL	2	helped to collect and prepare the samples for fiber quality exam and rna sequencing	helped to collect and prepare the samples for fiber quality exam and rna sequencing	Performed the experiments	Investigation	YES
5591532	28886694	WKG	2	critically reviewed the manuscript|helped to collect and prepare the samples for fiber quality exam and rna sequencing	critically reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5591532	28886694	WKG	2	critically reviewed the manuscript|helped to collect and prepare the samples for fiber quality exam and rna sequencing	helped to collect and prepare the samples for fiber quality exam and rna sequencing	Performed the experiments	Investigation	YES
5591532	28886694	WS	2	helped to collect and prepare the samples for fiber quality exam and rna sequencing	helped to collect and prepare the samples for fiber quality exam and rna sequencing	Performed the experiments	Investigation	YES
5591532	28886694	WWS	2	helped to collect and prepare the samples for fiber quality exam and rna sequencing	helped to collect and prepare the samples for fiber quality exam and rna sequencing	Performed the experiments	Investigation	YES
5591532	28886694	XPG	2	critically reviewed the manuscript	critically reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5591532	28886694	YLY	2	conceived and designed the study|critically reviewed the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5591532	28886694	YLY	2	conceived and designed the study|critically reviewed the manuscript	critically reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5591532	28886694	YZS	2	conceived and designed the study|critically reviewed the manuscript|analyzed the rna seq data	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5591532	28886694	YZS	2	conceived and designed the study|critically reviewed the manuscript|analyzed the rna seq data	critically reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5591532	28886694	YZS	2	conceived and designed the study|critically reviewed the manuscript|analyzed the rna seq data	analyzed the rna seq data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3874750	24148197	AMV	2	helped in data analysis and interpretation	helped in data analysis and interpretation	Analyzed the data	Formal analysis	YES
3874750	24148197	CDC	2	helped with data collection and contributed to data analysis and interpretation	helped with data collection and contributed to data analysis and interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3874750	24148197	CU	2	helped with statistical analysis and writing of the manuscript	helped with statistical analysis and writing of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3874750	24148197	JFF	2	helped in data analysis and interpretation	helped in data analysis and interpretation	Analyzed the data	Formal analysis	YES
3874750	24148197	MCZ	2	participated in data analysis and the writing of the manuscript	participated in data analysis and the writing of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3874750	24148197	MSA	2	designed the study and supervised the data collection, analysis, and helped with the writing of the manuscript	designed the study and supervised the data collection, analysis, and helped with the writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Supervision|Writing - Original Draft	YES
3874750	24148197	RVG	2	was responsible for data collection, data analysis and interpretation, and the writing of the draft	was responsible for data collection, data analysis and interpretation, and the writing of the draft	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5995766	29892792	EL	2	performed the statistical analysis and helped to draft the chapter handling statistics	performed the statistical analysis and helped to draft the chapter handling statistics	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5995766	29892792	HI	2	helped to draft the manuscript	helped to draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5995766	29892792	IM	2	performed the renal angiographies	performed the renal angiographies	Performed the experiments	Investigation	YES
5995766	29892792	JP	2	coordinated and conceived the study and drafted the manuscript	coordinated and conceived the study and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Project administration|Writing - Original Draft	YES
5995766	29892792	KL	2	did part of the modeling work on pet data	did part of the modeling work on pet data	Performed the experiments	Methodology	YES
5995766	29892792	KM	2	participated in the design of the study and helped to draft the manuscript	participated in the design of the study and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5995766	29892792	NK	2	collected data, participated in the design of the study, and helped to draft the manuscript	collected data, participated in the design of the study, and helped to draft the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5995766	29892792	PN	2	participated in the design of the study	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
5995766	29892792	VO	2	did part of the modeling work on pet data and helped to draft the chapter handling modeling	did part of the modeling work on pet data and helped to draft the chapter handling modeling	Performed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
1891090	17579713	JF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1891090	17579713	JF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1891090	17579713	JF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414478	25923208	CY	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4414478	25923208	CY	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4414478	25923208	DW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414478	25923208	DW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414478	25923208	DW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414478	25923208	DW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414478	25923208	JE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414478	25923208	JE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414478	25923208	JE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414478	25923208	JE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414478	25923208	JE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414478	25923208	JH	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4414478	25923208	JH	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4414478	25923208	SV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414478	25923208	SV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414478	25923208	SV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414478	25923208	SV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414478	25923208	SV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5723347	29259615	All authors	PLoS52	read, revised, and approved the final manuscript	read, revised, and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5723347	29259615	BA	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data and wrote the manuscript|revised the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5723347	29259615	BA	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data and wrote the manuscript|revised the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5723347	29259615	BA	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data and wrote the manuscript|revised the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5723347	29259615	BA	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data and wrote the manuscript|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5723347	29259615	CO	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5723347	29259615	HS	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5723347	29259615	JL	PLoS52	performed the experiments|contributed to the interpretation of the results	performed the experiments	Performed the experiments	Investigation	YES
5723347	29259615	JL	PLoS52	performed the experiments|contributed to the interpretation of the results	contributed to the interpretation of the results	Analyzed the data	Formal analysis	YES
5723347	29259615	JY	PLoS52	revised the manuscript|contributed to the interpretation of the results	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5723347	29259615	JY	PLoS52	revised the manuscript|contributed to the interpretation of the results	contributed to the interpretation of the results	Analyzed the data	Formal analysis	YES
5723347	29259615	SC	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5723347	29259615	XD	PLoS52	performed the experiments|contributed to the interpretation of the results	performed the experiments	Performed the experiments	Investigation	YES
5723347	29259615	XD	PLoS52	performed the experiments|contributed to the interpretation of the results	contributed to the interpretation of the results	Analyzed the data	Formal analysis	YES
5723347	29259615	YL	PLoS52	conceived and designed the experiments|revised the manuscript|contributed to the interpretation of the results	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5723347	29259615	YL	PLoS52	conceived and designed the experiments|revised the manuscript|contributed to the interpretation of the results	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5723347	29259615	YL	PLoS52	conceived and designed the experiments|revised the manuscript|contributed to the interpretation of the results	contributed to the interpretation of the results	Analyzed the data	Formal analysis	YES
3879660	24299050	AAA	2	performed the literature search, performed quality assessment, and coded the studies	performed the literature search, performed quality assessment, and coded the studies	Performed the experiments	Formal analysis|Investigation|Validation	YES
3879660	24299050	All authors	2	took part in writing the manuscript	took part in writing the manuscript	Wrote the paper	Writing - Original Draft	YES
3879660	24299050	BJS	2	performed the literature search, performed quality assessment, and coded the studies	performed the literature search, performed quality assessment, and coded the studies	Performed the experiments	Formal analysis|Investigation|Validation	YES
3879660	24299050	JWK	2	devised and carried out the statistical analysis	devised and carried out the statistical analysis	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
4609348	26504818	Bharat B. Mittal	2	conceived of the study, project design, oversaw data collection and analysis, and helped edit the paper	conceived of the study, project design, oversaw data collection and analysis, and helped edit the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Supervision|Writing - Review & Editing	YES
4609348	26504818	Estela Martinez-Escala	2	participated in data collection and analysis and helped to draft the paper	participated in data collection and analysis and helped to draft the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4609348	26504818	Joan Guitart	2	participated in project design, coordinated data collection, and helped edit the paper	participated in project design, coordinated data collection, and helped edit the paper	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Project administration|Writing - Review & Editing	YES
4609348	26504818	Michelle S. Gentile	2	carried out data collection and analysis and drafted the paper	carried out data collection and analysis and drafted the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4609348	26504818	Steven Rosen	2	participated in project design and helped edit the paper	participated in project design and helped edit the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
4609348	26504818	Tarita O. Thomas	2	carried out data collection and analysis	carried out data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4609348	26504818	Timothy Kuzel	2	participated in project design and helped edit the paper	participated in project design and helped edit the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
6024240	30034722	All authors	2	discussed the results, contributed to writing the manuscript and commented on it	discussed the results, contributed to writing the manuscript and commented on it	Wrote the paper	Writing - Original Draft	YES
6024240	30034722	D.D.V.B.B.	2	carried out the structure refinement	carried out the structure refinement	Performed the experiments	Investigation	YES
6024240	30034722	D.W.	2	performed the kp experiments	performed the kp experiments	Performed the experiments	Investigation	YES
6024240	30034722	H.R.	2	carried out the structure refinement	carried out the structure refinement	Performed the experiments	Investigation	YES
6024240	30034722	I.S.	2	developed the concept	developed the concept	Conceived and designed the experiments	Conceptualization	YES
6024240	30034722	J.F.M.O.	2	performed the kp experiments	performed the kp experiments	Performed the experiments	Investigation	YES
6024240	30034722	J.H.	2	conducted the dft calculations	conducted the dft calculations	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6024240	30034722	N.S.	2	carried out the structure refinement	carried out the structure refinement	Performed the experiments	Investigation	YES
6024240	30034722	P.M.V.	2	developed the concept	developed the concept	Conceived and designed the experiments	Conceptualization	YES
6024240	30034722	R.A.	2	developed the concept|carried out the structure refinement	developed the concept	Conceived and designed the experiments	Conceptualization	YES
6024240	30034722	R.A.	2	developed the concept|carried out the structure refinement	carried out the structure refinement	Performed the experiments	Investigation	YES
6024240	30034722	R.V.S.	2	developed the concept	developed the concept	Conceived and designed the experiments	Conceptualization	YES
6024240	30034722	V.V.S.	2	conducted the dft calculations	conducted the dft calculations	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5591550	28886691	ADM	2	participated at the conception and design of the work and acquisition of data	participated at the conception and design of the work and acquisition of data	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5591550	28886691	All authors	2	reviewed and approved the final version of the manuscript	reviewed and approved the final version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5591550	28886691	DB	2	participated at the conception and design of the work and acquisition of data|performed the analysis and interpretation of data, and drafting of the work	participated at the conception and design of the work and acquisition of data	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5591550	28886691	DB	2	participated at the conception and design of the work and acquisition of data|performed the analysis and interpretation of data, and drafting of the work	performed the analysis and interpretation of data, and drafting of the work	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5591550	28886691	LT	2	participated at the conception and design of the work and acquisition of data|performed the analysis and interpretation of data, and drafting of the work	participated at the conception and design of the work and acquisition of data	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5591550	28886691	LT	2	participated at the conception and design of the work and acquisition of data|performed the analysis and interpretation of data, and drafting of the work	performed the analysis and interpretation of data, and drafting of the work	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5591550	28886691	LV	2	participated at the conception and design of the work and acquisition of data	participated at the conception and design of the work and acquisition of data	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5591550	28886691	MEC	2	participated at the conception and design of the work and acquisition of data	participated at the conception and design of the work and acquisition of data	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5591550	28886691	OC	2	participated at the conception and design of the work and acquisition of data	participated at the conception and design of the work and acquisition of data	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5591550	28886691	SA	2	critically revised and participated to the analysis and interpretation of data	critically revised and participated to the analysis and interpretation of data	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5995767	29892810	AH	2	contributed to the data analysis and interpretation|contributed to the conception and design|contributed to the data analysis and interpretation|contributed to the manuscript preparation and revision	contributed to the data analysis and interpretation	Analyzed the data	Formal analysis	YES
5995767	29892810	AH	2	contributed to the data analysis and interpretation|contributed to the conception and design|contributed to the data analysis and interpretation|contributed to the manuscript preparation and revision	contributed to the conception and design	Conceived and designed the experiments	Conceptualization	YES
5995767	29892810	AH	2	contributed to the data analysis and interpretation|contributed to the conception and design|contributed to the data analysis and interpretation|contributed to the manuscript preparation and revision	contributed to the data analysis and interpretation	Analyzed the data	Formal analysis	YES
5995767	29892810	AH	2	contributed to the data analysis and interpretation|contributed to the conception and design|contributed to the data analysis and interpretation|contributed to the manuscript preparation and revision	contributed to the manuscript preparation and revision	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5995767	29892810	CJM	2	contributed to the conception and design|contributed to the data acquisition|contributed to the data analysis and interpretation|contributed to the conception and design|contributed to the data analysis and interpretation|contributed to the manuscript preparation and revision	contributed to the conception and design	Conceived and designed the experiments	Conceptualization	YES
5995767	29892810	CJM	2	contributed to the conception and design|contributed to the data acquisition|contributed to the data analysis and interpretation|contributed to the conception and design|contributed to the data analysis and interpretation|contributed to the manuscript preparation and revision	contributed to the data acquisition	Performed the experiments	Investigation	YES
5995767	29892810	CJM	2	contributed to the conception and design|contributed to the data acquisition|contributed to the data analysis and interpretation|contributed to the conception and design|contributed to the data analysis and interpretation|contributed to the manuscript preparation and revision	contributed to the data analysis and interpretation	Analyzed the data	Formal analysis	YES
5995767	29892810	CJM	2	contributed to the conception and design|contributed to the data acquisition|contributed to the data analysis and interpretation|contributed to the conception and design|contributed to the data analysis and interpretation|contributed to the manuscript preparation and revision	contributed to the conception and design	Conceived and designed the experiments	Conceptualization	YES
5995767	29892810	CJM	2	contributed to the conception and design|contributed to the data acquisition|contributed to the data analysis and interpretation|contributed to the conception and design|contributed to the data analysis and interpretation|contributed to the manuscript preparation and revision	contributed to the data analysis and interpretation	Analyzed the data	Formal analysis	YES
5995767	29892810	CJM	2	contributed to the conception and design|contributed to the data acquisition|contributed to the data analysis and interpretation|contributed to the conception and design|contributed to the data analysis and interpretation|contributed to the manuscript preparation and revision	contributed to the manuscript preparation and revision	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5995767	29892810	DARB	2	contributed to the data acquisition|contributed to the manuscript preparation and revision	contributed to the data acquisition	Performed the experiments	Investigation	YES
5995767	29892810	DARB	2	contributed to the data acquisition|contributed to the manuscript preparation and revision	contributed to the manuscript preparation and revision	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5995767	29892810	DJB	2	contributed to the conception and design|contributed to the data analysis and interpretation|contributed to the manuscript preparation and revision	contributed to the conception and design	Conceived and designed the experiments	Conceptualization	YES
5995767	29892810	DJB	2	contributed to the conception and design|contributed to the data analysis and interpretation|contributed to the manuscript preparation and revision	contributed to the data analysis and interpretation	Analyzed the data	Formal analysis	YES
5995767	29892810	DJB	2	contributed to the conception and design|contributed to the data analysis and interpretation|contributed to the manuscript preparation and revision	contributed to the manuscript preparation and revision	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5995767	29892810	JSD	2	contributed to the conception and design|contributed to the data acquisition|contributed to the data analysis and interpretation|contributed to the data analysis and interpretation|contributed to the manuscript preparation and revision	contributed to the conception and design	Conceived and designed the experiments	Conceptualization	YES
5995767	29892810	JSD	2	contributed to the conception and design|contributed to the data acquisition|contributed to the data analysis and interpretation|contributed to the data analysis and interpretation|contributed to the manuscript preparation and revision	contributed to the data acquisition	Performed the experiments	Investigation	YES
5995767	29892810	JSD	2	contributed to the conception and design|contributed to the data acquisition|contributed to the data analysis and interpretation|contributed to the data analysis and interpretation|contributed to the manuscript preparation and revision	contributed to the data analysis and interpretation	Analyzed the data	Formal analysis	YES
5995767	29892810	JSD	2	contributed to the conception and design|contributed to the data acquisition|contributed to the data analysis and interpretation|contributed to the data analysis and interpretation|contributed to the manuscript preparation and revision	contributed to the data analysis and interpretation	Analyzed the data	Formal analysis	YES
5995767	29892810	JSD	2	contributed to the conception and design|contributed to the data acquisition|contributed to the data analysis and interpretation|contributed to the data analysis and interpretation|contributed to the manuscript preparation and revision	contributed to the manuscript preparation and revision	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5995767	29892810	MJK	2	contributed to the conception and design|contributed to the data analysis and interpretation|contributed to the data analysis and interpretation|contributed to the manuscript preparation and revision	contributed to the conception and design	Conceived and designed the experiments	Conceptualization	YES
5995767	29892810	MJK	2	contributed to the conception and design|contributed to the data analysis and interpretation|contributed to the data analysis and interpretation|contributed to the manuscript preparation and revision	contributed to the data analysis and interpretation	Analyzed the data	Formal analysis	YES
5995767	29892810	MJK	2	contributed to the conception and design|contributed to the data analysis and interpretation|contributed to the data analysis and interpretation|contributed to the manuscript preparation and revision	contributed to the data analysis and interpretation	Analyzed the data	Formal analysis	YES
5995767	29892810	MJK	2	contributed to the conception and design|contributed to the data analysis and interpretation|contributed to the data analysis and interpretation|contributed to the manuscript preparation and revision	contributed to the manuscript preparation and revision	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5995767	29892810	RH	2	contributed to the data analysis and interpretation|contributed to the manuscript preparation and revision	contributed to the data analysis and interpretation	Analyzed the data	Formal analysis	YES
5995767	29892810	RH	2	contributed to the data analysis and interpretation|contributed to the manuscript preparation and revision	contributed to the manuscript preparation and revision	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5995767	29892810	WT	2	contributed to the conception and design|contributed to the data acquisition|contributed to the data analysis and interpretation|contributed to the data analysis and interpretation|contributed to the manuscript preparation and revision	contributed to the conception and design	Conceived and designed the experiments	Conceptualization	YES
5995767	29892810	WT	2	contributed to the conception and design|contributed to the data acquisition|contributed to the data analysis and interpretation|contributed to the data analysis and interpretation|contributed to the manuscript preparation and revision	contributed to the data acquisition	Performed the experiments	Investigation	YES
5995767	29892810	WT	2	contributed to the conception and design|contributed to the data acquisition|contributed to the data analysis and interpretation|contributed to the data analysis and interpretation|contributed to the manuscript preparation and revision	contributed to the data analysis and interpretation	Analyzed the data	Formal analysis	YES
5995767	29892810	WT	2	contributed to the conception and design|contributed to the data acquisition|contributed to the data analysis and interpretation|contributed to the data analysis and interpretation|contributed to the manuscript preparation and revision	contributed to the data analysis and interpretation	Analyzed the data	Formal analysis	YES
5995767	29892810	WT	2	contributed to the conception and design|contributed to the data acquisition|contributed to the data analysis and interpretation|contributed to the data analysis and interpretation|contributed to the manuscript preparation and revision	contributed to the manuscript preparation and revision	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5723387	29259618	P-HS	2	designed the experiments, performed fluorescence spectrometer measurements, data processing and manuscript writing	designed the experiments, performed fluorescence spectrometer measurements, data processing and manuscript writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Investigation|Methodology|Writing - Original Draft	YES
5723387	29259618	Y-HL	2	contributed to the isolation of intact chloroplasts and the operation of laser confocal microscopy	contributed to the isolation of intact chloroplasts and the operation of laser confocal microscopy	Performed the experiments	Investigation	YES
1891091	17579723	AN	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1891091	17579723	AN	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1891091	17579723	AN	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1891091	17579723	EB	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1891091	17579723	EB	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1891091	17579723	EB	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1891091	17579723	GN	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1891091	17579723	GN	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1891091	17579723	JS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1891091	17579723	JS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1891091	17579723	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1891091	17579723	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1891091	17579723	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1891091	17579723	PS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1891091	17579723	PS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1891091	17579723	PS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1891091	17579723	PS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3929155	24512517	AZ	2	participated in the practical measurement in all field studies	participated in the practical measurement in all field studies	Performed the experiments	Investigation	YES
3929155	24512517	BK	2	developed the objectives of the study and intervention|lead the drafting of the manuscript, interpreted the findings and critically reviewed the manuscript	developed the objectives of the study and intervention	-	-	NO
3929155	24512517	BK	2	developed the objectives of the study and intervention|lead the drafting of the manuscript, interpreted the findings and critically reviewed the manuscript	lead the drafting of the manuscript, interpreted the findings and critically reviewed the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
3929155	24512517	DCH	2	developed the objectives of the study and intervention|managed recruitment and data collection|participated in the practical measurement in all field studies|performed statistical analysis|lead the drafting of the manuscript, interpreted the findings and critically reviewed the manuscript	developed the objectives of the study and intervention	-	-	NO
3929155	24512517	DCH	2	developed the objectives of the study and intervention|managed recruitment and data collection|participated in the practical measurement in all field studies|performed statistical analysis|lead the drafting of the manuscript, interpreted the findings and critically reviewed the manuscript	managed recruitment and data collection	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
3929155	24512517	DCH	2	developed the objectives of the study and intervention|managed recruitment and data collection|participated in the practical measurement in all field studies|performed statistical analysis|lead the drafting of the manuscript, interpreted the findings and critically reviewed the manuscript	participated in the practical measurement in all field studies	Performed the experiments	Investigation	YES
3929155	24512517	DCH	2	developed the objectives of the study and intervention|managed recruitment and data collection|participated in the practical measurement in all field studies|performed statistical analysis|lead the drafting of the manuscript, interpreted the findings and critically reviewed the manuscript	performed statistical analysis	Analyzed the data	Formal analysis	YES
3929155	24512517	DCH	2	developed the objectives of the study and intervention|managed recruitment and data collection|participated in the practical measurement in all field studies|performed statistical analysis|lead the drafting of the manuscript, interpreted the findings and critically reviewed the manuscript	lead the drafting of the manuscript, interpreted the findings and critically reviewed the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
3929155	24512517	IT	2	performed statistical analysis	performed statistical analysis	Analyzed the data	Formal analysis	YES
3929155	24512517	TR	2	lead the drafting of the manuscript, interpreted the findings and critically reviewed the manuscript	lead the drafting of the manuscript, interpreted the findings and critically reviewed the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
4414479	25923660	AJT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414479	25923660	AJT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414479	25923660	AJT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414479	25923660	AJT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414479	25923660	BSP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414479	25923660	BSP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414479	25923660	BSP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414479	25923660	BSP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414479	25923660	BSP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414479	25923660	DEW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414479	25923660	DEW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414479	25923660	DEW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414479	25923660	ENE	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414479	25923660	ENE	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414479	25923660	ENE	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414479	25923660	GMC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414479	25923660	GMC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414479	25923660	GMC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414479	25923660	JN	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414479	25923660	JN	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414479	25923660	JN	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414479	25923660	LRF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414479	25923660	LRF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414479	25923660	LRF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414479	25923660	LRF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5594438	28893182	BYS	2	participated in the experiments	participated in the experiments	Performed the experiments	Investigation	YES
5594438	28893182	QZ	2	contributed to the analysis and interpretation of data, participated in the experiments and drafted the manuscript	contributed to the analysis and interpretation of data, participated in the experiments and drafted the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft	YES
5594438	28893182	WS	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5594438	28893182	YX	2	provided the sample strains	provided the sample strains	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5594438	28893182	ZZ	2	designed the study|supervised the study and drafted and revised the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5594438	28893182	ZZ	2	designed the study|supervised the study and drafted and revised the manuscript	supervised the study and drafted and revised the manuscript	Wrote the paper	Supervision|Writing - Original Draft|Writing - Review & Editing	YES
5995768	29892963	AB	4	or both were provided by|The drafting or critical revision for important intellectual content of the manuscript were conducted by|The statistical analysis of the data was done by	or both were provided by	-	-	NO
5995768	29892963	AB	4	or both were provided by|The drafting or critical revision for important intellectual content of the manuscript were conducted by|The statistical analysis of the data was done by	The drafting or critical revision for important intellectual content of the manuscript were conducted by	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5995768	29892963	AB	4	or both were provided by|The drafting or critical revision for important intellectual content of the manuscript were conducted by|The statistical analysis of the data was done by	The statistical analysis of the data was done by	Analyzed the data	Formal analysis	YES
5995768	29892963	AO	4	The image analysis and experimental processing were contributed by	The image analysis and experimental processing were contributed by	Analyzed the data	Visualization	YES
5995768	29892963	AR	4	The image analysis and experimental processing were contributed by	The image analysis and experimental processing were contributed by	Analyzed the data	Visualization	YES
5995768	29892963	CM	4	or both were provided by|The drafting or critical revision for important intellectual content of the manuscript were conducted by|The critical revision of the manuscript content was furnished by|The statistical analysis of the data was done by	or both were provided by	-	-	NO
5995768	29892963	CM	4	or both were provided by|The drafting or critical revision for important intellectual content of the manuscript were conducted by|The critical revision of the manuscript content was furnished by|The statistical analysis of the data was done by	The drafting or critical revision for important intellectual content of the manuscript were conducted by	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5995768	29892963	CM	4	or both were provided by|The drafting or critical revision for important intellectual content of the manuscript were conducted by|The critical revision of the manuscript content was furnished by|The statistical analysis of the data was done by	The critical revision of the manuscript content was furnished by	Wrote the paper	Writing - Review & Editing	YES
5995768	29892963	CM	4	or both were provided by|The drafting or critical revision for important intellectual content of the manuscript were conducted by|The critical revision of the manuscript content was furnished by|The statistical analysis of the data was done by	The statistical analysis of the data was done by	Analyzed the data	Formal analysis	YES
5995768	29892963	FB	4	The critical revision of the manuscript content was furnished by	The critical revision of the manuscript content was furnished by	Wrote the paper	Writing - Review & Editing	YES
5995768	29892963	FDG	4	The image analysis and experimental processing were contributed by	The image analysis and experimental processing were contributed by	Analyzed the data	Visualization	YES
5995768	29892963	FF	4	The image analysis and experimental processing were contributed by	The image analysis and experimental processing were contributed by	Analyzed the data	Visualization	YES
5995768	29892963	FG	4	The image analysis and experimental processing were contributed by	The image analysis and experimental processing were contributed by	Analyzed the data	Visualization	YES
5995768	29892963	FN	4	The critical revision of the manuscript content was furnished by	The critical revision of the manuscript content was furnished by	Wrote the paper	Writing - Review & Editing	YES
5995768	29892963	GB	4	The image analysis and experimental processing were contributed by	The image analysis and experimental processing were contributed by	Analyzed the data	Visualization	YES
5995768	29892963	GC	4	The critical revision of the manuscript content was furnished by	The critical revision of the manuscript content was furnished by	Wrote the paper	Writing - Review & Editing	YES
5995768	29892963	GMS	4	or both were provided by|The drafting or critical revision for important intellectual content of the manuscript were conducted by|The critical revision of the manuscript content was furnished by|The statistical analysis of the data was done by	or both were provided by	-	-	NO
5995768	29892963	GMS	4	or both were provided by|The drafting or critical revision for important intellectual content of the manuscript were conducted by|The critical revision of the manuscript content was furnished by|The statistical analysis of the data was done by	The drafting or critical revision for important intellectual content of the manuscript were conducted by	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5995768	29892963	GMS	4	or both were provided by|The drafting or critical revision for important intellectual content of the manuscript were conducted by|The critical revision of the manuscript content was furnished by|The statistical analysis of the data was done by	The critical revision of the manuscript content was furnished by	Wrote the paper	Writing - Review & Editing	YES
5995768	29892963	GMS	4	or both were provided by|The drafting or critical revision for important intellectual content of the manuscript were conducted by|The critical revision of the manuscript content was furnished by|The statistical analysis of the data was done by	The statistical analysis of the data was done by	Analyzed the data	Formal analysis	YES
5995768	29892963	LE	4	The image analysis and experimental processing were contributed by	The image analysis and experimental processing were contributed by	Analyzed the data	Visualization	YES
5995768	29892963	LR	4	The image analysis and experimental processing were contributed by	The image analysis and experimental processing were contributed by	Analyzed the data	Visualization	YES
5995768	29892963	MB	4	The drafting or critical revision for important intellectual content of the manuscript were conducted by|The statistical analysis of the data was done by	The drafting or critical revision for important intellectual content of the manuscript were conducted by	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5995768	29892963	MB	4	The drafting or critical revision for important intellectual content of the manuscript were conducted by|The statistical analysis of the data was done by	The statistical analysis of the data was done by	Analyzed the data	Formal analysis	YES
5995768	29892963	MP	4	The critical revision of the manuscript content was furnished by	The critical revision of the manuscript content was furnished by	Wrote the paper	Writing - Review & Editing	YES
5995768	29892963	PP	4	The image analysis and experimental processing were contributed by	The image analysis and experimental processing were contributed by	Analyzed the data	Visualization	YES
5995768	29892963	SB	4	The image analysis and experimental processing were contributed by	The image analysis and experimental processing were contributed by	Analyzed the data	Visualization	YES
5995768	29892963	SM	4	The critical revision of the manuscript content was furnished by	The critical revision of the manuscript content was furnished by	Wrote the paper	Writing - Review & Editing	YES
5995768	29892963	SR	4	The image analysis and experimental processing were contributed by|The critical revision of the manuscript content was furnished by	The image analysis and experimental processing were contributed by	Analyzed the data	Visualization	YES
5995768	29892963	SR	4	The image analysis and experimental processing were contributed by|The critical revision of the manuscript content was furnished by	The critical revision of the manuscript content was furnished by	Wrote the paper	Writing - Review & Editing	YES
5995768	29892963	VC	4	or both were provided by|The drafting or critical revision for important intellectual content of the manuscript were conducted by|The statistical analysis of the data was done by	or both were provided by	-	-	NO
5995768	29892963	VC	4	or both were provided by|The drafting or critical revision for important intellectual content of the manuscript were conducted by|The statistical analysis of the data was done by	The drafting or critical revision for important intellectual content of the manuscript were conducted by	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5995768	29892963	VC	4	or both were provided by|The drafting or critical revision for important intellectual content of the manuscript were conducted by|The statistical analysis of the data was done by	The statistical analysis of the data was done by	Analyzed the data	Formal analysis	YES
3937107	24447726	DD	2	assisted in the study design, interpretation of data, and critically reviewed the manuscript	assisted in the study design, interpretation of data, and critically reviewed the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
3937107	24447726	GB	2	assisted in the study design, interpretation of data, and critically reviewed the manuscript	assisted in the study design, interpretation of data, and critically reviewed the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
3937107	24447726	MN	2	developed the study design, collected data, conducted statistical analysis, and drafted and submitted the manuscript	developed the study design, collected data, conducted statistical analysis, and drafted and submitted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5723390	29259617	CZ	2	helped to set up experiments	helped to set up experiments	Performed the experiments	Investigation|Methodology	YES
5723390	29259617	GL	2	performed the wet lab work and data analysis, and drafted the manuscript	performed the wet lab work and data analysis, and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5723390	29259617	JY	2	conceived the idea, participated in the design of the study and finalized the manuscript	conceived the idea, participated in the design of the study and finalized the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
5723390	29259617	LG	2	conceived the idea, participated in the design of the study and finalized the manuscript	conceived the idea, participated in the design of the study and finalized the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
5723390	29259617	WZ	2	participated in data analysis	participated in data analysis	Analyzed the data	Formal analysis	YES
5723390	29259617	YD	2	helped to set up experiments	helped to set up experiments	Performed the experiments	Investigation|Methodology	YES
5723390	29259617	YG	2	helped to set up experiments	helped to set up experiments	Performed the experiments	Investigation|Methodology	YES
5723390	29259617	YW	2	participated in data analysis	participated in data analysis	Analyzed the data	Formal analysis	YES
5723390	29259617	ZS	2	participated in data analysis	participated in data analysis	Analyzed the data	Formal analysis	YES
1891092	17579724	CP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1891092	17579724	CP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1891092	17579724	MA	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1891092	17579724	MA	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1891092	17579724	MR	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1891092	17579724	MR	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1891092	17579724	PC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1891092	17579724	PC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1891092	17579724	PC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1891092	17579724	PC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414480	25923909	FH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414480	25923909	FH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414480	25923909	FH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414480	25923909	FH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414480	25923909	JS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414480	25923909	JS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414480	25923909	JS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414480	25923909	LH	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414480	25923909	LH	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414480	25923909	RER	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414480	25923909	RER	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414480	25923909	RER	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414480	25923909	RER	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414480	25923909	RER	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5594474	28893186	AG	2	performed the computational experiments	performed the computational experiments	Performed the experiments	Formal analysis|Investigation	YES
5594474	28893186	AM	2	performed the computational experiments	performed the computational experiments	Performed the experiments	Formal analysis|Investigation	YES
5594474	28893186	AZ	2	designed the study and developed the methodology|performed the computational experiments|wrote the manuscript	designed the study and developed the methodology	Conceived and designed the experiments|Performed the experiments	Methodology	YES
5594474	28893186	AZ	2	designed the study and developed the methodology|performed the computational experiments|wrote the manuscript	performed the computational experiments	Performed the experiments	Formal analysis|Investigation	YES
5594474	28893186	AZ	2	designed the study and developed the methodology|performed the computational experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5594474	28893186	EB	2	designed the study and developed the methodology	designed the study and developed the methodology	Conceived and designed the experiments|Performed the experiments	Methodology	YES
5594474	28893186	LC	2	designed the study and developed the methodology|performed the computational experiments|wrote the manuscript	designed the study and developed the methodology	Conceived and designed the experiments|Performed the experiments	Methodology	YES
5594474	28893186	LC	2	designed the study and developed the methodology|performed the computational experiments|wrote the manuscript	performed the computational experiments	Performed the experiments	Formal analysis|Investigation	YES
5594474	28893186	LC	2	designed the study and developed the methodology|performed the computational experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5594474	28893186	UC	2	performed the computational experiments|wrote the manuscript	performed the computational experiments	Performed the experiments	Formal analysis|Investigation	YES
5594474	28893186	UC	2	performed the computational experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5594474	28893186	UK	2	designed the study and developed the methodology|performed the computational experiments|wrote the manuscript	designed the study and developed the methodology	Conceived and designed the experiments|Performed the experiments	Methodology	YES
5594474	28893186	UK	2	designed the study and developed the methodology|performed the computational experiments|wrote the manuscript	performed the computational experiments	Performed the experiments	Formal analysis|Investigation	YES
5594474	28893186	UK	2	designed the study and developed the methodology|performed the computational experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5594474	28893186	all authors	2	read, approved and edited the manuscript	read, approved and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5999593	29900481	All authors	PLoS52	contributed substantially to the scientific process leading to this manuscript	contributed substantially to the scientific process leading to this manuscript	-	-	NO
5999593	29900481	CS	PLoS52	acquired data	acquired data	Performed the experiments	Investigation	YES
5999593	29900481	HT	PLoS52	critically contributed to the manuscript	critically contributed to the manuscript	-	-	NO
5999593	29900481	KK	PLoS52	prepared the pet radioligand	prepared the pet radioligand	-	-	NO
5999593	29900481	KY	PLoS52	acquired data	acquired data	Performed the experiments	Investigation	YES
5999593	29900481	MH	PLoS52	critically contributed to the manuscript	critically contributed to the manuscript	-	-	NO
5999593	29900481	MI	PLoS52	analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
5999593	29900481	MRZ	PLoS52	prepared the pet radioligand	prepared the pet radioligand	-	-	NO
5999593	29900481	MY	PLoS52	contributed to the design of the study|analysed the data|drafted the manuscript	contributed to the design of the study	Conceived and designed the experiments	Methodology	YES
5999593	29900481	MY	PLoS52	contributed to the design of the study|analysed the data|drafted the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
5999593	29900481	MY	PLoS52	contributed to the design of the study|analysed the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5999593	29900481	TI	PLoS52	contributed to the design of the study|acquired data|analysed the data|drafted the manuscript	contributed to the design of the study	Conceived and designed the experiments	Methodology	YES
5999593	29900481	TI	PLoS52	contributed to the design of the study|acquired data|analysed the data|drafted the manuscript	acquired data	Performed the experiments	Investigation	YES
5999593	29900481	TI	PLoS52	contributed to the design of the study|acquired data|analysed the data|drafted the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
5999593	29900481	TI	PLoS52	contributed to the design of the study|acquired data|analysed the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5999593	29900481	TS	PLoS52	critically contributed to the manuscript	critically contributed to the manuscript	-	-	NO
5999593	29900481	YK	PLoS52	contributed to the design of the study|acquired data|analysed the data|drafted the manuscript	contributed to the design of the study	Conceived and designed the experiments	Methodology	YES
5999593	29900481	YK	PLoS52	contributed to the design of the study|acquired data|analysed the data|drafted the manuscript	acquired data	Performed the experiments	Investigation	YES
5999593	29900481	YK	PLoS52	contributed to the design of the study|acquired data|analysed the data|drafted the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
5999593	29900481	YK	PLoS52	contributed to the design of the study|acquired data|analysed the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4870530	27179529	ARC	2	helped to design the experiments, performed all the experimental work, analysed and interpreted data and wrote the manuscript	helped to design the experiments, performed all the experimental work, analysed and interpreted data and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4870530	27179529	All authors	2	contributed intellectually via scientific discussions during the work and have been involved in drafting the manuscript and revising it critically for important intellectual content|read and approved the final manuscript	contributed intellectually via scientific discussions during the work and have been involved in drafting the manuscript and revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4870530	27179529	All authors	2	contributed intellectually via scientific discussions during the work and have been involved in drafting the manuscript and revising it critically for important intellectual content|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4870530	27179529	IR	2	participated in the interpretation of data and reviewed the manuscript	participated in the interpretation of data and reviewed the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4870530	27179529	MAP	2	designed the experiments, supervised all the experimental work, contributed to data interpretation and reviewed the manuscript	designed the experiments, supervised all the experimental work, contributed to data interpretation and reviewed the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Supervision|Writing - Review & Editing	YES
4870530	27179529	MMA	2	participated in the interpretation of data and reviewed the manuscript	participated in the interpretation of data and reviewed the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4870530	27179529	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
3943438	24571926	AES	2	conceived, drafted and revised the manuscript	conceived, drafted and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
3943438	24571926	ETT	2	conceived of the review topic and drafted the manuscript	conceived of the review topic and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
3943438	24571926	LEN	2	helped to draft and revise the manuscript	helped to draft and revise the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5723393	29259610	AE	7	designed the research and wrote the manuscript	designed the research and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5723393	29259610	AH-T	7	designed the research, did the analysis, and wrote the manuscript	designed the research, did the analysis, and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5723393	29259610	AW	7	designed the research and wrote the manuscript	designed the research and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5723393	29259610	MB	7	designed the research and revised previous versions of the manuscript	designed the research and revised previous versions of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5723393	29259610	RL	7	designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
1891093	17579715	JT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1891093	17579715	JT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1891093	17579715	JT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1891093	17579715	JT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1891093	17579715	JT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3945952	24565110	CN	2	carried out the animal studies and participated in the samples measurement	carried out the animal studies and participated in the samples measurement	Performed the experiments	Investigation	YES
3945952	24565110	JL	2	performed the statistical analysis and helped to draft the manuscript|sconceived of the study, and participated in its design and coordination	performed the statistical analysis and helped to draft the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3945952	24565110	JL	2	performed the statistical analysis and helped to draft the manuscript|sconceived of the study, and participated in its design and coordination	sconceived of the study, and participated in its design and coordination	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
3945952	24565110	NL	2	sconceived of the study, and participated in its design and coordination	sconceived of the study, and participated in its design and coordination	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
3945952	24565110	XW	2	carried out the animal studies and participated in the samples measurement|drafted the manuscript	carried out the animal studies and participated in the samples measurement	Performed the experiments	Investigation	YES
3945952	24565110	XW	2	carried out the animal studies and participated in the samples measurement|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5999598	29900520	F-FBPA	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5999598	29900520	FH	2	performed the pet data analyses	performed the pet data analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5999598	29900520	HT	2	participated in the study coordination and the design of the study and drafted the manuscript	participated in the study coordination and the design of the study and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft	YES
5999598	29900520	TK	2	performed the animal care and pet measurements	performed the animal care and pet measurements	Performed the experiments	Investigation	YES
4870535	27184362	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4870535	27184362	DBL	2	submitted the manuscript, tables, and figures	submitted the manuscript, tables, and figures	-	Visualization	YES
4870535	27184362	PKS	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4870535	27184362	VS	2	conducted data analyses	conducted data analyses	Analyzed the data	Formal analysis	YES
4414481	25923698	BZ	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414481	25923698	HL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4414481	25923698	SW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4414481	25923698	TJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414481	25923698	TJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414481	25923698	TJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414481	25923698	TJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414481	25923698	TJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414481	25923698	WH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414481	25923698	WH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414481	25923698	WH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414481	25923698	WH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414481	25923698	XW	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5594485	28893190	AT	2	prepared the samples|analyzed and interpreted the data|prepared the manuscript draft	prepared the samples	Performed the experiments	Investigation	YES
5594485	28893190	AT	2	prepared the samples|analyzed and interpreted the data|prepared the manuscript draft	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5594485	28893190	AT	2	prepared the samples|analyzed and interpreted the data|prepared the manuscript draft	prepared the manuscript draft	Wrote the paper	Writing - Original Draft	YES
5594485	28893190	All authors	2	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5594485	28893190	CZ	2	processed the microarray	processed the microarray	Performed the experiments	Investigation	YES
5594485	28893190	WXL	2	analyzed and interpreted the data|prepared the manuscript draft	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5594485	28893190	WXL	2	analyzed and interpreted the data|prepared the manuscript draft	prepared the manuscript draft	Wrote the paper	Writing - Original Draft	YES
3975841	24589205	All authors	2	were involved in the study	were involved in the study	-	-	NO
3975841	24589205	JDR	2	was the principal researcher, involved with liaison with the company, participant assessment, data collection, statistical analysis and manuscript generation	was the principal researcher, involved with liaison with the company, participant assessment, data collection, statistical analysis and manuscript generation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3975841	24589205	LSK	2	was involved with monitoring of data collection including collation of performance data, and test beverage administration, as well as manuscript editing	was involved with monitoring of data collection including collation of performance data, and test beverage administration, as well as manuscript editing	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Review & Editing	YES
3975841	24589205	MDT	2	was co-researcher involved with cohort organization, data collection and blood analyses, confirmation of statistical analyses, and manuscript editing	was co-researcher involved with cohort organization, data collection and blood analyses, confirmation of statistical analyses, and manuscript editing	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
3975841	24589205	MGR	2	was involved in quality control, data collection, and technical accuracy in preparation of the manuscript	was involved in quality control, data collection, and technical accuracy in preparation of the manuscript	Performed the experiments|Wrote the paper	Investigation|Validation|Writing - Original Draft	YES
3975841	24589205	RJT	2	was involved with data collection and analysis	was involved with data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5723400	29259609	all authors	2	edited and reviewed manuscript	edited and reviewed manuscript	Wrote the paper	Writing - Review & Editing	YES
1891433	17593958	IW	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1891433	17593958	RP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1891433	17593958	SP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1891433	17593958	SP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1891433	17593958	SP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1891433	17593958	SS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
6002329	29904817	AD	2	participated in the acquisition of the data	participated in the acquisition of the data	Performed the experiments	Investigation	YES
6002329	29904817	ALB	2	carried out the analysis and interpretation of the data|drafted the manuscript	carried out the analysis and interpretation of the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6002329	29904817	ALB	2	carried out the analysis and interpretation of the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
6002329	29904817	EG	2	participated in the acquisition of the data	participated in the acquisition of the data	Performed the experiments	Investigation	YES
6002329	29904817	FLJ	2	participated in the acquisition of the data	participated in the acquisition of the data	Performed the experiments	Investigation	YES
6002329	29904817	GG	2	provided their critical revision of the manuscript	provided their critical revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
6002329	29904817	HSJ	2	conceived and designed the study|provided their critical revision of the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6002329	29904817	HSJ	2	conceived and designed the study|provided their critical revision of the manuscript	provided their critical revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
6002329	29904817	PB	2	provided their critical revision of the manuscript	provided their critical revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
6002329	29904817	PYS	2	provided their critical revision of the manuscript	provided their critical revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
6002329	29904817	SQ	2	provided their critical revision of the manuscript	provided their critical revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
6002329	29904817	XPN	2	conceived and designed the study|carried out the analysis and interpretation of the data|drafted the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6002329	29904817	XPN	2	conceived and designed the study|carried out the analysis and interpretation of the data|drafted the manuscript	carried out the analysis and interpretation of the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6002329	29904817	XPN	2	conceived and designed the study|carried out the analysis and interpretation of the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4875572	27207069	JZ	1	Experiment planning and design|Paper construction	Experiment planning and design	Conceived and designed the experiments	Methodology	YES
4875572	27207069	JZ	1	Experiment planning and design|Paper construction	Paper construction	Performed the experiments	Investigation	YES
4875572	27207069	LS	1	Sampling collection and analysis	Sampling collection and analysis	Performed the experiments	Investigation	YES
4875572	27207069	QS	1	Experiment planning and design	Experiment planning and design	Conceived and designed the experiments	Methodology	YES
4875572	27207069	SL	1	Experiment planning and design|Paper construction	Experiment planning and design	Conceived and designed the experiments	Methodology	YES
4875572	27207069	SL	1	Experiment planning and design|Paper construction	Paper construction	Performed the experiments	Investigation	YES
4875572	27207069	Shuqing Li	1	Experiment planning and design|Paper construction	Experiment planning and design	Conceived and designed the experiments	Methodology	YES
4875572	27207069	Shuqing Li	1	Experiment planning and design|Paper construction	Paper construction	Performed the experiments	Investigation	YES
4875572	27207069	YJ	1	Sampling collection and analysis	Sampling collection and analysis	Performed the experiments	Investigation	YES
4414482	25923220	FX	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414482	25923220	LZ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414482	25923220	LZ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414482	25923220	LZ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414482	25923220	MSG	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414482	25923220	MSG	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414482	25923220	MSG	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414482	25923220	TL	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414482	25923220	YL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
3975949	24552143	AN	2	participated in the interpretation and preparation of the manuscript	participated in the interpretation and preparation of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3975949	24552143	ANB	2	participated in the interpretation and preparation of the manuscript	participated in the interpretation and preparation of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3975949	24552143	CLD	2	participate in the manuscript design and wrote the first draft of the manuscript	participate in the manuscript design and wrote the first draft of the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
3975949	24552143	HN	2	participated in the manuscript design, interpretation and preparation of the manuscript	participated in the manuscript design, interpretation and preparation of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3975949	24552143	NM	2	participated in the interpretation and preparation of the manuscript	participated in the interpretation and preparation of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3975949	24552143	RAC	2	participated in the interpretation and preparation of the manuscript	participated in the interpretation and preparation of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3975949	24552143	VP	2	participated in the interpretation and preparation of the manuscript	participated in the interpretation and preparation of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5594505	28893177	BSL	2	participated in the design of the study and discussed the results|carried out bioinformatics analyses	participated in the design of the study and discussed the results	Conceived and designed the experiments	Methodology	YES
5594505	28893177	BSL	2	participated in the design of the study and discussed the results|carried out bioinformatics analyses	carried out bioinformatics analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5594505	28893177	GFZ	2	conceived the project|participated in the design of the study and discussed the results	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5594505	28893177	GFZ	2	conceived the project|participated in the design of the study and discussed the results	participated in the design of the study and discussed the results	Conceived and designed the experiments	Methodology	YES
5594505	28893177	JM	2	conceived the project|participated in the design of the study and discussed the results	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5594505	28893177	JM	2	conceived the project|participated in the design of the study and discussed the results	participated in the design of the study and discussed the results	Conceived and designed the experiments	Methodology	YES
5594505	28893177	KS	2	participated in the design of the study and discussed the results|carried out bioinformatics analyses	participated in the design of the study and discussed the results	Conceived and designed the experiments	Methodology	YES
5594505	28893177	KS	2	participated in the design of the study and discussed the results|carried out bioinformatics analyses	carried out bioinformatics analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5594505	28893177	LL	2	conceived the project|participated in the design of the study and discussed the results	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5594505	28893177	LL	2	conceived the project|participated in the design of the study and discussed the results	participated in the design of the study and discussed the results	Conceived and designed the experiments	Methodology	YES
5723404	29259613	All authors	2	have contributed substantially in conceiving the idea, and designing and interpretation of the work|have made significant contribution to the preparation and revision of drafts, and have given final approval for publication	have contributed substantially in conceiving the idea, and designing and interpretation of the work	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
5723404	29259613	All authors	2	have contributed substantially in conceiving the idea, and designing and interpretation of the work|have made significant contribution to the preparation and revision of drafts, and have given final approval for publication	have made significant contribution to the preparation and revision of drafts, and have given final approval for publication	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3975968	24568653	ARJ	2	assisted in data collection and statistical analysis	assisted in data collection and statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3975968	24568653	CM	2	served as a collaborating scientist	served as a collaborating scientist	-	-	NO
3975968	24568653	CR	2	served as lab coordinator and oversaw data collection and quality control of the study	served as lab coordinator and oversaw data collection and quality control of the study	Performed the experiments	Data curation|Investigation|Project administration|Supervision|Validation	YES
3975968	24568653	IP	2	assisted in the experimental design, data analysis, and manuscript preparation	assisted in the experimental design, data analysis, and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
3975968	24568653	JF	2	supervised the biopsy procedures	supervised the biopsy procedures	Performed the experiments	Investigation|Supervision	YES
3975968	24568653	JMO	2	served as the study coordinator, oversaw all testing, and assisted in data analysis and writing of the manuscript	served as the study coordinator, oversaw all testing, and assisted in data analysis and writing of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Project administration|Supervision|Writing - Original Draft	YES
3975968	24568653	MG	2	assisted in experimental design, data analysis, and manuscript preparation	assisted in experimental design, data analysis, and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
3975968	24568653	MP	2	assisted in the experimental design, data analysis, and manuscript preparation	assisted in the experimental design, data analysis, and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
3975968	24568653	RBK	2	served as principal investigator and contributed to the design of the study, statistical analysis, manuscript preparation, and procurement of external funding	served as principal investigator and contributed to the design of the study, statistical analysis, manuscript preparation, and procurement of external funding	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Funding acquisition|Methodology|Writing - Original Draft	YES
3975968	24568653	RJ	2	assisted in the experimental design, data analysis, and manuscript preparation	assisted in the experimental design, data analysis, and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
3975968	24568653	SR	2	supervised the biopsy procedures	supervised the biopsy procedures	Performed the experiments	Investigation|Supervision	YES
1891434	17593966	AW	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1891434	17593966	MM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1891434	17593966	MM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1891434	17593966	MN	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1891434	17593966	MV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1891434	17593966	MV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1891434	17593966	MV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1891434	17593966	MV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1891434	17593966	MW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1891434	17593966	MW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
6003894	29904822	BAS	2	critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
6003894	29904822	DF	2	assisted with clinical data collection and analysis and revised the manuscript	assisted with clinical data collection and analysis and revised the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
6003894	29904822	FD	2	critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
6003894	29904822	JKS	2	assisted with study design and revised the manuscript	assisted with study design and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
6003894	29904822	JMF	2	participated in the study design, data collection, and analysis	participated in the study design, data collection, and analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
6003894	29904822	KJF	2	participated in the data collection and revised the manuscript	participated in the data collection and revised the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
6003894	29904822	PWG	2	participated in the study design, clinical data collection, and revised the manuscript	participated in the study design, clinical data collection, and revised the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
6003894	29904822	RLW	2	critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
6003894	29904822	TAD	2	assisted with statistical analysis and revised and edited the manuscript	assisted with statistical analysis and revised and edited the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4609355	26504804	Lan Wang	2	contributed equally to this work	contributed equally to this work	-	-	NO
4609355	26504804	Zhong Cheng	2	contributed equally to this work	contributed equally to this work	-	-	NO
5723407	29259616	CL	PLoS52	conceived the research|performed the experiments	conceived the research	Conceived and designed the experiments	Conceptualization	YES
5723407	29259616	CL	PLoS52	conceived the research|performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5723407	29259616	LS	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5723407	29259616	ML	PLoS52	conceived the research|provided scientific suggestions, and revised the manuscript	conceived the research	Conceived and designed the experiments	Conceptualization	YES
5723407	29259616	ML	PLoS52	conceived the research|provided scientific suggestions, and revised the manuscript	provided scientific suggestions, and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5723407	29259616	XQ	PLoS52	conceived the research|designed the experiments|performed the experiments|analyzed the results, and wrote the manuscript	conceived the research	Conceived and designed the experiments	Conceptualization	YES
5723407	29259616	XQ	PLoS52	conceived the research|designed the experiments|performed the experiments|analyzed the results, and wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5723407	29259616	XQ	PLoS52	conceived the research|designed the experiments|performed the experiments|analyzed the results, and wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5723407	29259616	XQ	PLoS52	conceived the research|designed the experiments|performed the experiments|analyzed the results, and wrote the manuscript	analyzed the results, and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5723407	29259616	YL	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
3983672	24716994	DSM	2	helped draft the manuscript|assisted with data collection and data analysis	helped draft the manuscript	Wrote the paper	Writing - Original Draft	YES
3983672	24716994	DSM	2	helped draft the manuscript|assisted with data collection and data analysis	assisted with data collection and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3983672	24716994	GH	2	assisted in the design of the study	assisted in the design of the study	Conceived and designed the experiments	Methodology	YES
3983672	24716994	GL	2	were the primary investigators, supervised all study recruitment and data analysis|assisted in the design of the study|assisted with data collection and data analysis	were the primary investigators, supervised all study recruitment and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Supervision	YES
3983672	24716994	GL	2	were the primary investigators, supervised all study recruitment and data analysis|assisted in the design of the study|assisted with data collection and data analysis	assisted in the design of the study	Conceived and designed the experiments	Methodology	YES
3983672	24716994	GL	2	were the primary investigators, supervised all study recruitment and data analysis|assisted in the design of the study|assisted with data collection and data analysis	assisted with data collection and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3983672	24716994	IO	2	were the primary investigators, supervised all study recruitment and data analysis|assisted in the design of the study|helped draft the manuscript|assisted with data collection and data analysis	were the primary investigators, supervised all study recruitment and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Supervision	YES
3983672	24716994	IO	2	were the primary investigators, supervised all study recruitment and data analysis|assisted in the design of the study|helped draft the manuscript|assisted with data collection and data analysis	assisted in the design of the study	Conceived and designed the experiments	Methodology	YES
3983672	24716994	IO	2	were the primary investigators, supervised all study recruitment and data analysis|assisted in the design of the study|helped draft the manuscript|assisted with data collection and data analysis	helped draft the manuscript	Wrote the paper	Writing - Original Draft	YES
3983672	24716994	IO	2	were the primary investigators, supervised all study recruitment and data analysis|assisted in the design of the study|helped draft the manuscript|assisted with data collection and data analysis	assisted with data collection and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3983672	24716994	JRH	2	were the primary investigators, supervised all study recruitment and data analysis|assisted in the design of the study|performed the statistical analysis|supervised the manuscript preparation|helped draft the manuscript|assisted with data collection and data analysis	were the primary investigators, supervised all study recruitment and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Supervision	YES
3983672	24716994	JRH	2	were the primary investigators, supervised all study recruitment and data analysis|assisted in the design of the study|performed the statistical analysis|supervised the manuscript preparation|helped draft the manuscript|assisted with data collection and data analysis	assisted in the design of the study	Conceived and designed the experiments	Methodology	YES
3983672	24716994	JRH	2	were the primary investigators, supervised all study recruitment and data analysis|assisted in the design of the study|performed the statistical analysis|supervised the manuscript preparation|helped draft the manuscript|assisted with data collection and data analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
3983672	24716994	JRH	2	were the primary investigators, supervised all study recruitment and data analysis|assisted in the design of the study|performed the statistical analysis|supervised the manuscript preparation|helped draft the manuscript|assisted with data collection and data analysis	supervised the manuscript preparation	Wrote the paper	Supervision|Writing - Original Draft	YES
3983672	24716994	JRH	2	were the primary investigators, supervised all study recruitment and data analysis|assisted in the design of the study|performed the statistical analysis|supervised the manuscript preparation|helped draft the manuscript|assisted with data collection and data analysis	helped draft the manuscript	Wrote the paper	Writing - Original Draft	YES
3983672	24716994	JRH	2	were the primary investigators, supervised all study recruitment and data analysis|assisted in the design of the study|performed the statistical analysis|supervised the manuscript preparation|helped draft the manuscript|assisted with data collection and data analysis	assisted with data collection and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3983672	24716994	JRS	2	assisted in the design of the study|performed the statistical analysis|helped draft the manuscript	assisted in the design of the study	Conceived and designed the experiments	Methodology	YES
3983672	24716994	JRS	2	assisted in the design of the study|performed the statistical analysis|helped draft the manuscript	performed the statistical analysis	Analyzed the data	Formal analysis	YES
3983672	24716994	JRS	2	assisted in the design of the study|performed the statistical analysis|helped draft the manuscript	helped draft the manuscript	Wrote the paper	Writing - Original Draft	YES
3983672	24716994	MD	2	assisted in the design of the study	assisted in the design of the study	Conceived and designed the experiments	Methodology	YES
3983672	24716994	MWH	2	assisted with data collection and data analysis	assisted with data collection and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3983672	24716994	NS	2	assisted with data collection and data analysis	assisted with data collection and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3983672	24716994	WPM	2	assisted with data collection and data analysis	assisted with data collection and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3983672	24716994	YBM	2	assisted in the design of the study	assisted in the design of the study	Conceived and designed the experiments	Methodology	YES
1891435	17593959	AB	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1891435	17593959	AK	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1891435	17593959	AK	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1891435	17593959	FP	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1891435	17593959	ID	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1891435	17593959	II	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1891435	17593959	II	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1891435	17593959	II	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1891435	17593959	II	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1891435	17593959	IS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1891435	17593959	SK	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1891435	17593959	SV	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1891435	17593959	SV	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1891435	17593959	SV	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1891435	17593959	TL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1891435	17593959	TL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1891435	17593959	VK	PLoS5	Analyzed the data|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1891435	17593959	VK	PLoS5	Analyzed the data|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1891435	17593959	VM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1891435	17593959	YY	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1891435	17593959	YY	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1891435	17593959	YY	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5594519	28893192	All the authors	2	reviewed, approved and contributed to the final version of this manuscript	reviewed, approved and contributed to the final version of this manuscript	Wrote the paper	Writing - Review & Editing	YES
5594519	28893192	CH	2	supervised the study	supervised the study	-	Supervision	YES
5594519	28893192	RL	2	performed the systematic review, all experiments, analysis and drafted the manuscript	performed the systematic review, all experiments, analysis and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5594519	28893192	WM	2	supervised the study	supervised the study	-	Supervision	YES
4414483	25923532	BA	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414483	25923532	BA	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414483	25923532	CZ	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414483	25923532	CZ	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414483	25923532	JS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414483	25923532	JS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414483	25923532	JS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414483	25923532	PYT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414483	25923532	PYT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414483	25923532	PYT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414483	25923532	VK	PLoS5	Analyzed the data|Wrote the paper|Drew figures	Analyzed the data	Analyzed the data	Formal analysis	YES
4414483	25923532	VK	PLoS5	Analyzed the data|Wrote the paper|Drew figures	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414483	25923532	VK	PLoS5	Analyzed the data|Wrote the paper|Drew figures	Drew figures	-	Visualization	YES
4414483	25923532	ZL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5723411	29259614	All authors	2	have made a substantial, direct and intellectual contribution to the work, and approved it for publication	have made a substantial, direct and intellectual contribution to the work, and approved it for publication	-	-	NO
5723411	29259614	FP	2	was a pivoting writer and improved articulation	was a pivoting writer and improved articulation	Wrote the paper	-	YES
5723411	29259614	OS	2	initiated the work	initiated the work	Conceived and designed the experiments	Conceptualization	YES
5723411	29259614	PW	2	elaborated on the case study of pine nuts	elaborated on the case study of pine nuts	-	-	NO
6003896	29904808	DO	2	helped in critically interpreting the data and in revising the manuscript	helped in critically interpreting the data and in revising the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
6003896	29904808	JDA	2	were the primary writers of the manuscript who performed data collection, analysis, and interpretation	were the primary writers of the manuscript who performed data collection, analysis, and interpretation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6003896	29904808	JKM	2	helped in data collection and in revising the manuscript	helped in data collection and in revising the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
6003896	29904808	JN	2	performed the phantom study, image reconstruction, and analysis and reviewed the manuscript	performed the phantom study, image reconstruction, and analysis and reviewed the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Investigation|Visualization|Writing - Review & Editing	YES
6003896	29904808	KAF	2	evaluated patient data, helped in clinical interpretation, and revised the manuscript	evaluated patient data, helped in clinical interpretation, and revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
6003896	29904808	YKD	2	were the primary writers of the manuscript who performed data collection, analysis, and interpretation	were the primary writers of the manuscript who performed data collection, analysis, and interpretation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3835877	24298218	Paton Piromchai	2	designed and supervised the research, collected, analysed, and interpreted the data, and drafted and revised the paper	designed and supervised the research, collected, analysed, and interpreted the data, and drafted and revised the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
3835877	24298218	Sanguansak Thanaviratananich	2	made substantial contributions to the design of the study and approved the final version of the paper	made substantial contributions to the design of the study and approved the final version of the paper	Conceived and designed the experiments	Methodology	YES
1891436	17593960	CK	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1891436	17593960	CK	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1891436	17593960	JR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1891436	17593960	JR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1891436	17593960	JR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1891436	17593960	JZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1891436	17593960	JZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1891436	17593960	JZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1891436	17593960	JZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1891436	17593960	MA	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1891436	17593960	MH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1891436	17593960	MK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1891436	17593960	MK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1891436	17593960	MK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1891436	17593960	SL	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1891436	17593960	TM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1891436	17593960	VM	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
3986904	24670105	OD	2	obtained grant funding for this project|conducted data collection and instructed research assistants in data entry|prepared this manuscript for publication	obtained grant funding for this project	-	Funding acquisition	YES
3986904	24670105	OD	2	obtained grant funding for this project|conducted data collection and instructed research assistants in data entry|prepared this manuscript for publication	conducted data collection and instructed research assistants in data entry	Performed the experiments|Analyzed the data	Data curation|Investigation|Supervision	YES
3986904	24670105	OD	2	obtained grant funding for this project|conducted data collection and instructed research assistants in data entry|prepared this manuscript for publication	prepared this manuscript for publication	Wrote the paper	Writing - Original Draft	YES
3986904	24670105	ZY	2	obtained grant funding for this project|prepared data files and conducted data analysis	obtained grant funding for this project	-	Funding acquisition	YES
3986904	24670105	ZY	2	obtained grant funding for this project|prepared data files and conducted data analysis	prepared data files and conducted data analysis	Analyzed the data	Formal analysis	YES
4414484	25923736	BXX	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4414484	25923736	BXX	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4414484	25923736	CQ	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4414484	25923736	CQ	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4414484	25923736	HYW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414484	25923736	HYW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414484	25923736	HYW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414484	25923736	SC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414484	25923736	SC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414484	25923736	SC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5723420	29259612	JC	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5723420	29259612	JS	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5723420	29259612	RZ	PLoS52	prepared all the samples|wrote the manuscript with contributions from all authors	prepared all the samples	Performed the experiments	Investigation	YES
5723420	29259612	RZ	PLoS52	prepared all the samples|wrote the manuscript with contributions from all authors	wrote the manuscript with contributions from all authors	Wrote the paper	Writing - Original Draft	YES
5723420	29259612	SH	PLoS52	contributed to the manuscript revision	contributed to the manuscript revision	Wrote the paper	Writing - Review & Editing	YES
5723420	29259612	SSR	PLoS52	primers and data analysis	primers and data analysis	Analyzed the data	Formal analysis	YES
5723420	29259612	TL	PLoS52	conceived and designed the experiments|contributed to the manuscript revision	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5723420	29259612	TL	PLoS52	conceived and designed the experiments|contributed to the manuscript revision	contributed to the manuscript revision	Wrote the paper	Writing - Review & Editing	YES
5723420	29259612	XZ	PLoS52	performed experiments and analyzed data|wrote the manuscript with contributions from all authors	performed experiments and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5723420	29259612	XZ	PLoS52	performed experiments and analyzed data|wrote the manuscript with contributions from all authors	wrote the manuscript with contributions from all authors	Wrote the paper	Writing - Original Draft	YES
5723420	29259612	YZ	PLoS52	helped with rt-pcr data collection	helped with rt-pcr data collection	Performed the experiments	Investigation	YES
5723420	29259612	YwZ	PLoS52	contributed to plant materials subculture	contributed to plant materials subculture	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
1891437	17593962	AA	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1891437	17593962	AO	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1891437	17593962	AO	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1891437	17593962	AO	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1891437	17593962	AO	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1891437	17593962	BD	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1891437	17593962	CC	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1891437	17593962	CC	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1891437	17593962	FF	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1891437	17593962	FF	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1891437	17593962	LN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1891437	17593962	LN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1891437	17593962	LN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1891437	17593962	LN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1891437	17593962	MB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1891437	17593962	MB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1891437	17593962	MB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1891437	17593962	MB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1891437	17593962	ZB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5594537	28893199	ABD	2	performed the data mining, data analysis	performed the data mining, data analysis	Analyzed the data	Formal analysis	YES
5594537	28893199	ABG	2	performed the data mining, data analysis	performed the data mining, data analysis	Analyzed the data	Formal analysis	YES
5594537	28893199	SAG	2	performed the data mining, data analysis|participated in the drafting of the manuscript	performed the data mining, data analysis	Analyzed the data	Formal analysis	YES
5594537	28893199	SAG	2	performed the data mining, data analysis|participated in the drafting of the manuscript	participated in the drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
5594537	28893199	TKM	2	conceived the study, coordinated the research and wrote the manuscript	conceived the study, coordinated the research and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Project administration|Writing - Original Draft	YES
6003898	29904818	AC	2	collaborated with the small animal experiments included in this research in mice and rats	collaborated with the small animal experiments included in this research in mice and rats	Performed the experiments	Investigation	YES
6003898	29904818	AR	2	participated in the ex vivo analyses, autoradiographic, and histological studies	participated in the ex vivo analyses, autoradiographic, and histological studies	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6003898	29904818	CC	2	performed the radionuclide-labeling of the peptides	performed the radionuclide-labeling of the peptides	Performed the experiments	Investigation	YES
6003898	29904818	FM	2	co-wrote the ethical request for project authorization, developed the study design, analyzed the data, and drafted the manuscript	co-wrote the ethical request for project authorization, developed the study design, analyzed the data, and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
6003898	29904818	GG	2	participated in the histological studies	participated in the histological studies	Performed the experiments	Investigation	YES
6003898	29904818	GK	2	contributed to manuscript revision and its approval	contributed to manuscript revision and its approval	Wrote the paper	Writing - Review & Editing	YES
6003898	29904818	JP	2	performed the experimental studies in mice	performed the experimental studies in mice	Performed the experiments	Investigation	YES
6003898	29904818	NV	2	performed the radionuclide-labeling of the peptides	performed the radionuclide-labeling of the peptides	Performed the experiments	Investigation	YES
6003898	29904818	PYM	2	co-wrote the manuscript and approved the final version of the manuscript	co-wrote the manuscript and approved the final version of the manuscript	Wrote the paper	Writing - Original Draft	YES
6003898	29904818	SI	2	performed the experimental studies in mice	performed the experimental studies in mice	Performed the experiments	Investigation	YES
6003898	29904818	SP	2	collaborated with the study design, co-wrote the ethical request for project authorization, and provided the animal models	collaborated with the study design, co-wrote the ethical request for project authorization, and provided the animal models	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
6003898	29904818	ST	2	participated in the autoradiographic analyses	participated in the autoradiographic analyses	Analyzed the data	Formal analysis	YES
6003898	29904818	SyP	2	participated in the ex vivo analyses	participated in the ex vivo analyses	Analyzed the data	Formal analysis	YES
4414485	25923442	MT	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414485	25923442	MT	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414485	25923442	QL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414485	25923442	QL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414485	25923442	QL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414485	25923442	QL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3991905	24716892	BD	7	Study concept and design, data analysis and interpretation, manuscript preparation	Study concept and design, data analysis and interpretation, manuscript preparation	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
3991905	24716892	DS	7	Study concept and design, measurement of hepcidin samples, manuscript preparation	Study concept and design, measurement of hepcidin samples, manuscript preparation	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Writing - Original Draft	YES
3991905	24716892	DT	7	Study concept and design, data analysis and interpretation, manuscript preparation	Study concept and design, data analysis and interpretation, manuscript preparation	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
3991905	24716892	EW	7	Study concept and design, measurement of hepcidin samples, manuscript preparation	Study concept and design, measurement of hepcidin samples, manuscript preparation	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Writing - Original Draft	YES
3991905	24716892	GL	7	Study concept and design, data analysis and interpretation, manuscript preparation	Study concept and design, data analysis and interpretation, manuscript preparation	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
3991905	24716892	HT	7	Study concept and design, measurement of hepcidin samples, manuscript preparation	Study concept and design, measurement of hepcidin samples, manuscript preparation	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Writing - Original Draft	YES
3991905	24716892	MS	7	Study concept and design, data collection and analysis, measurement of biological samples, manuscript preparation	Study concept and design, data collection and analysis, measurement of biological samples, manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
3991905	24716892	PP	7	Study concept and design, measurement of biological samples, data analysis and interpretation, manuscript preparation	Study concept and design, measurement of biological samples, data analysis and interpretation, manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4609358	26504807	Jae-Jun Ryu	2	contributed equally to this work	contributed equally to this work	-	-	NO
4609358	26504807	Nam-Ho Kim	2	contributed equally to this work	contributed equally to this work	-	-	NO
4609358	26504807	So-Hyoun Lee	2	contributed equally to this work	contributed equally to this work	-	-	NO
5723425	29259611	CO	2	conceived and designed the research project|the interpretation of images and analysis of data	conceived and designed the research project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5723425	29259611	CO	2	conceived and designed the research project|the interpretation of images and analysis of data	the interpretation of images and analysis of data	Analyzed the data	Formal analysis|Visualization	YES
5723425	29259611	JP	2	conceived and designed the research project|the interpretation of images and analysis of data	conceived and designed the research project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5723425	29259611	JP	2	conceived and designed the research project|the interpretation of images and analysis of data	the interpretation of images and analysis of data	Analyzed the data	Formal analysis|Visualization	YES
1891438	17593956	AT	1	Designed the study	Designed the study	Conceived and designed the experiments	Methodology	YES
1891438	17593956	HW	1	Conducted the laboratory studies	Conducted the laboratory studies	Performed the experiments	Investigation	YES
1891438	17593956	IE	1	Conducted the laboratory studies	Conducted the laboratory studies	Performed the experiments	Investigation	YES
1891438	17593956	JVdB	1	Project directors|Wrote the initial study protocol|Revised the study protocol|Designed the analysis plan and conducted the analysis|Drafted the manuscript	Project directors	-	-	NO
1891438	17593956	JVdB	1	Project directors|Wrote the initial study protocol|Revised the study protocol|Designed the analysis plan and conducted the analysis|Drafted the manuscript	Wrote the initial study protocol	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
1891438	17593956	JVdB	1	Project directors|Wrote the initial study protocol|Revised the study protocol|Designed the analysis plan and conducted the analysis|Drafted the manuscript	Revised the study protocol	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
1891438	17593956	JVdB	1	Project directors|Wrote the initial study protocol|Revised the study protocol|Designed the analysis plan and conducted the analysis|Drafted the manuscript	Designed the analysis plan and conducted the analysis	Conceived and designed the experiments|Performed the experiments	Investigation	YES
1891438	17593956	JVdB	1	Project directors|Wrote the initial study protocol|Revised the study protocol|Designed the analysis plan and conducted the analysis|Drafted the manuscript	Drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
1891438	17593956	KAL	1	Project directors|Revised the study protocol|Drafted the manuscript	Project directors	-	-	NO
1891438	17593956	KAL	1	Project directors|Revised the study protocol|Drafted the manuscript	Revised the study protocol	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
1891438	17593956	KAL	1	Project directors|Revised the study protocol|Drafted the manuscript	Drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
1891438	17593956	MLB	1	Principal investigator for the study|Designed the study|Wrote the grant proposal|Wrote the initial study protocol|Revised the study protocol|Designed the analysis plan and conducted the analysis|Drafted the manuscript	Principal investigator for the study	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
1891438	17593956	MLB	1	Principal investigator for the study|Designed the study|Wrote the grant proposal|Wrote the initial study protocol|Revised the study protocol|Designed the analysis plan and conducted the analysis|Drafted the manuscript	Designed the study	Conceived and designed the experiments	Methodology	YES
1891438	17593956	MLB	1	Principal investigator for the study|Designed the study|Wrote the grant proposal|Wrote the initial study protocol|Revised the study protocol|Designed the analysis plan and conducted the analysis|Drafted the manuscript	Wrote the grant proposal	Wrote the paper	Writing - Original Draft	YES
1891438	17593956	MLB	1	Principal investigator for the study|Designed the study|Wrote the grant proposal|Wrote the initial study protocol|Revised the study protocol|Designed the analysis plan and conducted the analysis|Drafted the manuscript	Wrote the initial study protocol	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
1891438	17593956	MLB	1	Principal investigator for the study|Designed the study|Wrote the grant proposal|Wrote the initial study protocol|Revised the study protocol|Designed the analysis plan and conducted the analysis|Drafted the manuscript	Revised the study protocol	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
1891438	17593956	MLB	1	Principal investigator for the study|Designed the study|Wrote the grant proposal|Wrote the initial study protocol|Revised the study protocol|Designed the analysis plan and conducted the analysis|Drafted the manuscript	Designed the analysis plan and conducted the analysis	Conceived and designed the experiments|Performed the experiments	Investigation	YES
1891438	17593956	MLB	1	Principal investigator for the study|Designed the study|Wrote the grant proposal|Wrote the initial study protocol|Revised the study protocol|Designed the analysis plan and conducted the analysis|Drafted the manuscript	Drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
1891438	17593956	MM	1	Conducted the laboratory studies	Conducted the laboratory studies	Performed the experiments	Investigation	YES
1891438	17593956	NM	1	Supervised the field work for the study	Supervised the field work for the study	Performed the experiments	Investigation|Supervision	YES
1891438	17593956	all authors	1	Critically reviewed and approved the manuscript	Critically reviewed and approved the manuscript	Wrote the paper	Writing - Review & Editing	YES
3994392	24655435	AJP	2	conception and design of research|performed experiments|analyzed data|interpreted results of experiments|prepared figures|drafted manuscript|edited and revised manuscript|approved final version of manuscript	conception and design of research	Conceived and designed the experiments	Conceptualization|Methodology	YES
3994392	24655435	AJP	2	conception and design of research|performed experiments|analyzed data|interpreted results of experiments|prepared figures|drafted manuscript|edited and revised manuscript|approved final version of manuscript	performed experiments	Performed the experiments	Investigation	YES
3994392	24655435	AJP	2	conception and design of research|performed experiments|analyzed data|interpreted results of experiments|prepared figures|drafted manuscript|edited and revised manuscript|approved final version of manuscript	analyzed data	Analyzed the data	Formal analysis	YES
3994392	24655435	AJP	2	conception and design of research|performed experiments|analyzed data|interpreted results of experiments|prepared figures|drafted manuscript|edited and revised manuscript|approved final version of manuscript	interpreted results of experiments	Analyzed the data	Formal analysis	YES
3994392	24655435	AJP	2	conception and design of research|performed experiments|analyzed data|interpreted results of experiments|prepared figures|drafted manuscript|edited and revised manuscript|approved final version of manuscript	prepared figures	-	Visualization	YES
3994392	24655435	AJP	2	conception and design of research|performed experiments|analyzed data|interpreted results of experiments|prepared figures|drafted manuscript|edited and revised manuscript|approved final version of manuscript	drafted manuscript	Wrote the paper	Writing - Original Draft	YES
3994392	24655435	AJP	2	conception and design of research|performed experiments|analyzed data|interpreted results of experiments|prepared figures|drafted manuscript|edited and revised manuscript|approved final version of manuscript	edited and revised manuscript	Wrote the paper	Writing - Review & Editing	YES
3994392	24655435	AJP	2	conception and design of research|performed experiments|analyzed data|interpreted results of experiments|prepared figures|drafted manuscript|edited and revised manuscript|approved final version of manuscript	approved final version of manuscript	-	-	NO
3994392	24655435	DDM	2	performed experiments|analyzed data|interpreted results of experiments|drafted manuscript|edited and revised manuscript|approved final version of manuscript	performed experiments	Performed the experiments	Investigation	YES
3994392	24655435	DDM	2	performed experiments|analyzed data|interpreted results of experiments|drafted manuscript|edited and revised manuscript|approved final version of manuscript	analyzed data	Analyzed the data	Formal analysis	YES
3994392	24655435	DDM	2	performed experiments|analyzed data|interpreted results of experiments|drafted manuscript|edited and revised manuscript|approved final version of manuscript	interpreted results of experiments	Analyzed the data	Formal analysis	YES
3994392	24655435	DDM	2	performed experiments|analyzed data|interpreted results of experiments|drafted manuscript|edited and revised manuscript|approved final version of manuscript	drafted manuscript	Wrote the paper	Writing - Original Draft	YES
3994392	24655435	DDM	2	performed experiments|analyzed data|interpreted results of experiments|drafted manuscript|edited and revised manuscript|approved final version of manuscript	edited and revised manuscript	Wrote the paper	Writing - Review & Editing	YES
3994392	24655435	DDM	2	performed experiments|analyzed data|interpreted results of experiments|drafted manuscript|edited and revised manuscript|approved final version of manuscript	approved final version of manuscript	-	-	NO
3994392	24655435	DZA	2	conception and design of research|performed experiments|analyzed data|interpreted results of experiments|prepared figures|drafted manuscript|edited and revised manuscript|approved final version of manuscript	conception and design of research	Conceived and designed the experiments	Conceptualization|Methodology	YES
3994392	24655435	DZA	2	conception and design of research|performed experiments|analyzed data|interpreted results of experiments|prepared figures|drafted manuscript|edited and revised manuscript|approved final version of manuscript	performed experiments	Performed the experiments	Investigation	YES
3994392	24655435	DZA	2	conception and design of research|performed experiments|analyzed data|interpreted results of experiments|prepared figures|drafted manuscript|edited and revised manuscript|approved final version of manuscript	analyzed data	Analyzed the data	Formal analysis	YES
3994392	24655435	DZA	2	conception and design of research|performed experiments|analyzed data|interpreted results of experiments|prepared figures|drafted manuscript|edited and revised manuscript|approved final version of manuscript	interpreted results of experiments	Analyzed the data	Formal analysis	YES
3994392	24655435	DZA	2	conception and design of research|performed experiments|analyzed data|interpreted results of experiments|prepared figures|drafted manuscript|edited and revised manuscript|approved final version of manuscript	prepared figures	-	Visualization	YES
3994392	24655435	DZA	2	conception and design of research|performed experiments|analyzed data|interpreted results of experiments|prepared figures|drafted manuscript|edited and revised manuscript|approved final version of manuscript	drafted manuscript	Wrote the paper	Writing - Original Draft	YES
3994392	24655435	DZA	2	conception and design of research|performed experiments|analyzed data|interpreted results of experiments|prepared figures|drafted manuscript|edited and revised manuscript|approved final version of manuscript	edited and revised manuscript	Wrote the paper	Writing - Review & Editing	YES
3994392	24655435	DZA	2	conception and design of research|performed experiments|analyzed data|interpreted results of experiments|prepared figures|drafted manuscript|edited and revised manuscript|approved final version of manuscript	approved final version of manuscript	-	-	NO
3994392	24655435	LPD	2	analyzed data|interpreted results of experiments|drafted manuscript|edited and revised manuscript|approved final version of manuscript	analyzed data	Analyzed the data	Formal analysis	YES
3994392	24655435	LPD	2	analyzed data|interpreted results of experiments|drafted manuscript|edited and revised manuscript|approved final version of manuscript	interpreted results of experiments	Analyzed the data	Formal analysis	YES
3994392	24655435	LPD	2	analyzed data|interpreted results of experiments|drafted manuscript|edited and revised manuscript|approved final version of manuscript	drafted manuscript	Wrote the paper	Writing - Original Draft	YES
3994392	24655435	LPD	2	analyzed data|interpreted results of experiments|drafted manuscript|edited and revised manuscript|approved final version of manuscript	edited and revised manuscript	Wrote the paper	Writing - Review & Editing	YES
3994392	24655435	LPD	2	analyzed data|interpreted results of experiments|drafted manuscript|edited and revised manuscript|approved final version of manuscript	approved final version of manuscript	-	-	NO
3994392	24655435	NRB	2	conception and design of research|performed experiments|analyzed data|interpreted results of experiments|prepared figures|drafted manuscript|edited and revised manuscript|approved final version of manuscript	conception and design of research	Conceived and designed the experiments	Conceptualization|Methodology	YES
3994392	24655435	NRB	2	conception and design of research|performed experiments|analyzed data|interpreted results of experiments|prepared figures|drafted manuscript|edited and revised manuscript|approved final version of manuscript	performed experiments	Performed the experiments	Investigation	YES
3994392	24655435	NRB	2	conception and design of research|performed experiments|analyzed data|interpreted results of experiments|prepared figures|drafted manuscript|edited and revised manuscript|approved final version of manuscript	analyzed data	Analyzed the data	Formal analysis	YES
3994392	24655435	NRB	2	conception and design of research|performed experiments|analyzed data|interpreted results of experiments|prepared figures|drafted manuscript|edited and revised manuscript|approved final version of manuscript	interpreted results of experiments	Analyzed the data	Formal analysis	YES
3994392	24655435	NRB	2	conception and design of research|performed experiments|analyzed data|interpreted results of experiments|prepared figures|drafted manuscript|edited and revised manuscript|approved final version of manuscript	prepared figures	-	Visualization	YES
3994392	24655435	NRB	2	conception and design of research|performed experiments|analyzed data|interpreted results of experiments|prepared figures|drafted manuscript|edited and revised manuscript|approved final version of manuscript	drafted manuscript	Wrote the paper	Writing - Original Draft	YES
3994392	24655435	NRB	2	conception and design of research|performed experiments|analyzed data|interpreted results of experiments|prepared figures|drafted manuscript|edited and revised manuscript|approved final version of manuscript	edited and revised manuscript	Wrote the paper	Writing - Review & Editing	YES
3994392	24655435	NRB	2	conception and design of research|performed experiments|analyzed data|interpreted results of experiments|prepared figures|drafted manuscript|edited and revised manuscript|approved final version of manuscript	approved final version of manuscript	-	-	NO
3994392	24655435	POM	2	performed experiments|analyzed data|interpreted results of experiments|drafted manuscript|edited and revised manuscript|approved final version of manuscript	performed experiments	Performed the experiments	Investigation	YES
3994392	24655435	POM	2	performed experiments|analyzed data|interpreted results of experiments|drafted manuscript|edited and revised manuscript|approved final version of manuscript	analyzed data	Analyzed the data	Formal analysis	YES
3994392	24655435	POM	2	performed experiments|analyzed data|interpreted results of experiments|drafted manuscript|edited and revised manuscript|approved final version of manuscript	interpreted results of experiments	Analyzed the data	Formal analysis	YES
3994392	24655435	POM	2	performed experiments|analyzed data|interpreted results of experiments|drafted manuscript|edited and revised manuscript|approved final version of manuscript	drafted manuscript	Wrote the paper	Writing - Original Draft	YES
3994392	24655435	POM	2	performed experiments|analyzed data|interpreted results of experiments|drafted manuscript|edited and revised manuscript|approved final version of manuscript	edited and revised manuscript	Wrote the paper	Writing - Review & Editing	YES
3994392	24655435	POM	2	performed experiments|analyzed data|interpreted results of experiments|drafted manuscript|edited and revised manuscript|approved final version of manuscript	approved final version of manuscript	-	-	NO
3994392	24655435	RRC	2	analyzed data|interpreted results of experiments|drafted manuscript|edited and revised manuscript|approved final version of manuscript	analyzed data	Analyzed the data	Formal analysis	YES
3994392	24655435	RRC	2	analyzed data|interpreted results of experiments|drafted manuscript|edited and revised manuscript|approved final version of manuscript	interpreted results of experiments	Analyzed the data	Formal analysis	YES
3994392	24655435	RRC	2	analyzed data|interpreted results of experiments|drafted manuscript|edited and revised manuscript|approved final version of manuscript	drafted manuscript	Wrote the paper	Writing - Original Draft	YES
3994392	24655435	RRC	2	analyzed data|interpreted results of experiments|drafted manuscript|edited and revised manuscript|approved final version of manuscript	edited and revised manuscript	Wrote the paper	Writing - Review & Editing	YES
3994392	24655435	RRC	2	analyzed data|interpreted results of experiments|drafted manuscript|edited and revised manuscript|approved final version of manuscript	approved final version of manuscript	-	-	NO
3994392	24655435	SGP	2	conception and design of research|performed experiments|analyzed data|interpreted results of experiments|prepared figures|drafted manuscript|edited and revised manuscript|approved final version of manuscript	conception and design of research	Conceived and designed the experiments	Conceptualization|Methodology	YES
3994392	24655435	SGP	2	conception and design of research|performed experiments|analyzed data|interpreted results of experiments|prepared figures|drafted manuscript|edited and revised manuscript|approved final version of manuscript	performed experiments	Performed the experiments	Investigation	YES
3994392	24655435	SGP	2	conception and design of research|performed experiments|analyzed data|interpreted results of experiments|prepared figures|drafted manuscript|edited and revised manuscript|approved final version of manuscript	analyzed data	Analyzed the data	Formal analysis	YES
3994392	24655435	SGP	2	conception and design of research|performed experiments|analyzed data|interpreted results of experiments|prepared figures|drafted manuscript|edited and revised manuscript|approved final version of manuscript	interpreted results of experiments	Analyzed the data	Formal analysis	YES
3994392	24655435	SGP	2	conception and design of research|performed experiments|analyzed data|interpreted results of experiments|prepared figures|drafted manuscript|edited and revised manuscript|approved final version of manuscript	prepared figures	-	Visualization	YES
3994392	24655435	SGP	2	conception and design of research|performed experiments|analyzed data|interpreted results of experiments|prepared figures|drafted manuscript|edited and revised manuscript|approved final version of manuscript	drafted manuscript	Wrote the paper	Writing - Original Draft	YES
3994392	24655435	SGP	2	conception and design of research|performed experiments|analyzed data|interpreted results of experiments|prepared figures|drafted manuscript|edited and revised manuscript|approved final version of manuscript	edited and revised manuscript	Wrote the paper	Writing - Review & Editing	YES
3994392	24655435	SGP	2	conception and design of research|performed experiments|analyzed data|interpreted results of experiments|prepared figures|drafted manuscript|edited and revised manuscript|approved final version of manuscript	approved final version of manuscript	-	-	NO
6005997	29916085	All authors	2	read, contributed to, and approved the final manuscript	read, contributed to, and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6005997	29916085	JLH	2	conceived of the study and participated in its design and coordination	conceived of the study and participated in its design and coordination	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
6005997	29916085	JR	2	planned the study, carried out the experiments, and helped to draft the manuscript	planned the study, carried out the experiments, and helped to draft the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
6005997	29916085	LF	2	participated in performing the experiments	participated in performing the experiments	Performed the experiments	Investigation	YES
6005997	29916085	MG	2	planned the study, carried out the experiments, and drafted the manuscript	planned the study, carried out the experiments, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
6005997	29916085	NVKP	2	performed the radiochemistry	performed the radiochemistry	Performed the experiments	Investigation	YES
4414486	25923111	HK	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414486	25923111	IT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414486	25923111	IT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414486	25923111	IT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414486	25923111	KH	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414486	25923111	RM	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4414486	25923111	RM	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4414486	25923111	SA	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4414486	25923111	SA	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414486	25923111	TN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414486	25923111	TN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414486	25923111	TN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414486	25923111	TN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414486	25923111	TN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414486	25923111	TW	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4414486	25923111	TW	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4414486	25923111	YH	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4414486	25923111	YH	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4414486	25923111	YU	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5594555	28893191	BK	2	provided critical reagents and rna sequencing data	provided critical reagents and rna sequencing data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5594555	28893191	JH	2	contributed to data analysis and manuscript writing	contributed to data analysis and manuscript writing	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5594555	28893191	MM	2	contributed to data analysis and manuscript writing	contributed to data analysis and manuscript writing	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5594555	28893191	RK	2	conceived the study, carried out most of the data analysis and drafted the manuscript	conceived the study, carried out most of the data analysis and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
5594555	28893191	SM	2	contributed to data analysis and manuscript writing|performed data mining and contributed to manuscript writing	contributed to data analysis and manuscript writing	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5594555	28893191	SM	2	contributed to data analysis and manuscript writing|performed data mining and contributed to manuscript writing	performed data mining and contributed to manuscript writing	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5594555	28893191	WZ	2	performed data mining and contributed to manuscript writing	performed data mining and contributed to manuscript writing	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5594555	28893191	XH	2	provided critical reagents and rna sequencing data	provided critical reagents and rna sequencing data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
1891439	17593957	AA	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1891439	17593957	AA	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1891439	17593957	AA	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1891439	17593957	AA	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1891439	17593957	AP	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1891439	17593957	AP	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1891439	17593957	AP	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1891439	17593957	AP	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1891439	17593957	BB	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1891439	17593957	BB	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1891439	17593957	BB	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1891439	17593957	BB	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1891439	17593957	BP	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1891439	17593957	BP	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1891439	17593957	BP	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1891439	17593957	BP	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1891439	17593957	BY	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1891439	17593957	BY	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1891439	17593957	BY	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1891439	17593957	BY	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1891439	17593957	CD	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1891439	17593957	CD	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1891439	17593957	CD	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1891439	17593957	CD	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1891439	17593957	JC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Helped write the paper	Performed the experiments	Performed the experiments	Investigation	YES
1891439	17593957	JC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Helped write the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1891439	17593957	JC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Helped write the paper	Helped write the paper	Wrote the paper	Writing - Original Draft	YES
1891439	17593957	JD	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1891439	17593957	JD	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1891439	17593957	JD	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1891439	17593957	JD	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1891439	17593957	JF	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1891439	17593957	JF	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1891439	17593957	JF	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1891439	17593957	JF	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1891439	17593957	KS	PLoS5	Analyzed the data|Helped write the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1891439	17593957	KS	PLoS5	Analyzed the data|Helped write the paper	Helped write the paper	Wrote the paper	Writing - Original Draft	YES
1891439	17593957	MZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1891439	17593957	MZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1891439	17593957	MZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1891439	17593957	MZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1891439	17593957	SD	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Helped write the paper	Performed the experiments	Performed the experiments	Investigation	YES
1891439	17593957	SD	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Helped write the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1891439	17593957	SD	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Helped write the paper	Helped write the paper	Wrote the paper	Writing - Original Draft	YES
5723429	29259608	CaS	2	processed samples, and analyzed data	processed samples, and analyzed data	Analyzed the data	Data curation|Formal analysis	YES
5723429	29259608	CoS	2	processed samples, analyzed data and wrote the manuscript	processed samples, analyzed data and wrote the manuscript	Analyzed the data|Wrote the paper	Data curation|Formal analysis|Writing - Original Draft	YES
5723429	29259608	DL	2	processed samples, analyzed data and wrote the manuscript	processed samples, analyzed data and wrote the manuscript	Analyzed the data|Wrote the paper	Data curation|Formal analysis|Writing - Original Draft	YES
5723429	29259608	DR	2	processed samples, and analyzed data	processed samples, and analyzed data	Analyzed the data	Data curation|Formal analysis	YES
5723429	29259608	FA	2	processed samples, and analyzed data	processed samples, and analyzed data	Analyzed the data	Data curation|Formal analysis	YES
5723429	29259608	FF	2	analyzed data and wrote the manuscript	analyzed data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5723429	29259608	GM	2	processed samples, analyzed data and wrote the manuscript	processed samples, analyzed data and wrote the manuscript	Analyzed the data|Wrote the paper	Data curation|Formal analysis|Writing - Original Draft	YES
5723429	29259608	JM	2	conceived experiment, analyzed data and wrote the manuscript	conceived experiment, analyzed data and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
5723429	29259608	KM	2	processed samples, analyzed data	processed samples, analyzed data	Analyzed the data	Data curation|Formal analysis	YES
5723429	29259608	OC	2	processed samples, analyzed data	processed samples, analyzed data	Analyzed the data	Data curation|Formal analysis	YES
3994394	24661412	MS	2	helped with translation and the extensively correction of the whole text	helped with translation and the extensively correction of the whole text	-	-	NO
4414496	25922947	AD	PLoS5	Contributed reagents/materials/analysis tools|Discussed the results and contributed to the final manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414496	25922947	AD	PLoS5	Contributed reagents/materials/analysis tools|Discussed the results and contributed to the final manuscript	Discussed the results and contributed to the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4414496	25922947	BA	PLoS5	Performed the statistical analyses|Discussed the results and contributed to the final manuscript	Performed the statistical analyses	Analyzed the data	Formal analysis	YES
4414496	25922947	BA	PLoS5	Performed the statistical analyses|Discussed the results and contributed to the final manuscript	Discussed the results and contributed to the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4414496	25922947	GF	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Discussed the results and contributed to the final manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4414496	25922947	GF	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Discussed the results and contributed to the final manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414496	25922947	GF	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Discussed the results and contributed to the final manuscript	Discussed the results and contributed to the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4414496	25922947	JA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Performed the scale and water glucocorticoid analyses|Discussed the results and contributed to the final manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414496	25922947	JA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Performed the scale and water glucocorticoid analyses|Discussed the results and contributed to the final manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4414496	25922947	JA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Performed the scale and water glucocorticoid analyses|Discussed the results and contributed to the final manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414496	25922947	JA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Performed the scale and water glucocorticoid analyses|Discussed the results and contributed to the final manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414496	25922947	JA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Performed the scale and water glucocorticoid analyses|Discussed the results and contributed to the final manuscript	Performed the scale and water glucocorticoid analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4414496	25922947	JA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Performed the scale and water glucocorticoid analyses|Discussed the results and contributed to the final manuscript	Discussed the results and contributed to the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4414496	25922947	JM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Performed the blood, scale morphometric and gene analyses|Discussed the results and contributed to the final manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4414496	25922947	JM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Performed the blood, scale morphometric and gene analyses|Discussed the results and contributed to the final manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4414496	25922947	JM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Performed the blood, scale morphometric and gene analyses|Discussed the results and contributed to the final manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414496	25922947	JM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Performed the blood, scale morphometric and gene analyses|Discussed the results and contributed to the final manuscript	Performed the blood, scale morphometric and gene analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4414496	25922947	JM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Performed the blood, scale morphometric and gene analyses|Discussed the results and contributed to the final manuscript	Discussed the results and contributed to the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4414496	25922947	SDS	PLoS5	Contributed reagents/materials/analysis tools|Discussed the results and contributed to the final manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414496	25922947	SDS	PLoS5	Contributed reagents/materials/analysis tools|Discussed the results and contributed to the final manuscript	Discussed the results and contributed to the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4609361	26504806	INFO	2	template, and performed first draft data analysis and interpretation	template, and performed first draft data analysis and interpretation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4609361	26504806	Wubegzier Mekonnen	2	designed the study and selected the study area|checked the data analysis and interpretation, supervised the whole process, and made critical comments at each step in the research process and approved the final draft of the paper	designed the study and selected the study area	Conceived and designed the experiments	Methodology	YES
4609361	26504806	Wubegzier Mekonnen	2	designed the study and selected the study area|checked the data analysis and interpretation, supervised the whole process, and made critical comments at each step in the research process and approved the final draft of the paper	checked the data analysis and interpretation, supervised the whole process, and made critical comments at each step in the research process and approved the final draft of the paper	Analyzed the data|Wrote the paper	Data curation|Formal analysis|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
6008272	29923139	ABT	2	conceived and designed the present study|developed methodology|analyzed and interpreted the data|reviewed and revised the manuscript|supervised the overall project	conceived and designed the present study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6008272	29923139	ABT	2	conceived and designed the present study|developed methodology|analyzed and interpreted the data|reviewed and revised the manuscript|supervised the overall project	developed methodology	Performed the experiments	Methodology	YES
6008272	29923139	ABT	2	conceived and designed the present study|developed methodology|analyzed and interpreted the data|reviewed and revised the manuscript|supervised the overall project	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
6008272	29923139	ABT	2	conceived and designed the present study|developed methodology|analyzed and interpreted the data|reviewed and revised the manuscript|supervised the overall project	reviewed and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
6008272	29923139	ABT	2	conceived and designed the present study|developed methodology|analyzed and interpreted the data|reviewed and revised the manuscript|supervised the overall project	supervised the overall project	-	Supervision	YES
6008272	29923139	AS	2	acquired the data|provided administrative and material support	acquired the data	Performed the experiments	Investigation	YES
6008272	29923139	AS	2	acquired the data|provided administrative and material support	provided administrative and material support	Contributed reagents/materials/analysis tools	Project administration|Resources	YES
6008272	29923139	DB	2	developed methodology|provided the technical and material support|reviewed and revised the manuscript	developed methodology	Performed the experiments	Methodology	YES
6008272	29923139	DB	2	developed methodology|provided the technical and material support|reviewed and revised the manuscript	provided the technical and material support	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
6008272	29923139	DB	2	developed methodology|provided the technical and material support|reviewed and revised the manuscript	reviewed and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
6008272	29923139	KN	2	acquired the data|provided the technical and material support	acquired the data	Performed the experiments	Investigation	YES
6008272	29923139	KN	2	acquired the data|provided the technical and material support	provided the technical and material support	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
6008272	29923139	MD	2	acquired the data|analyzed and interpreted the data|provided the technical and material support	acquired the data	Performed the experiments	Investigation	YES
6008272	29923139	MD	2	acquired the data|analyzed and interpreted the data|provided the technical and material support	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
6008272	29923139	MD	2	acquired the data|analyzed and interpreted the data|provided the technical and material support	provided the technical and material support	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
6008272	29923139	MRZ	2	acquired the data|provided administrative and material support	acquired the data	Performed the experiments	Investigation	YES
6008272	29923139	MRZ	2	acquired the data|provided administrative and material support	provided administrative and material support	Contributed reagents/materials/analysis tools	Project administration|Resources	YES
6008272	29923139	PD	2	provided the technical and material support|reviewed and revised the manuscript	provided the technical and material support	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
6008272	29923139	PD	2	provided the technical and material support|reviewed and revised the manuscript	reviewed and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
6008272	29923139	TH	2	reviewed and revised the manuscript|supervised the overall project	reviewed and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
6008272	29923139	TH	2	reviewed and revised the manuscript|supervised the overall project	supervised the overall project	-	Supervision	YES
6008272	29923139	YF	2	developed methodology|reviewed and revised the manuscript	developed methodology	Performed the experiments	Methodology	YES
6008272	29923139	YF	2	developed methodology|reviewed and revised the manuscript	reviewed and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
6008272	29923139	YY	2	analyzed and interpreted the data|provided the technical and material support	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
6008272	29923139	YY	2	analyzed and interpreted the data|provided the technical and material support	provided the technical and material support	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
6008272	29923139	ZHJ	2	conceived and designed the present study|developed methodology|acquired the data|analyzed and interpreted the data|created the figures and tables, drafted and revised the manuscript	conceived and designed the present study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6008272	29923139	ZHJ	2	conceived and designed the present study|developed methodology|acquired the data|analyzed and interpreted the data|created the figures and tables, drafted and revised the manuscript	developed methodology	Performed the experiments	Methodology	YES
6008272	29923139	ZHJ	2	conceived and designed the present study|developed methodology|acquired the data|analyzed and interpreted the data|created the figures and tables, drafted and revised the manuscript	acquired the data	Performed the experiments	Investigation	YES
6008272	29923139	ZHJ	2	conceived and designed the present study|developed methodology|acquired the data|analyzed and interpreted the data|created the figures and tables, drafted and revised the manuscript	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
6008272	29923139	ZHJ	2	conceived and designed the present study|developed methodology|acquired the data|analyzed and interpreted the data|created the figures and tables, drafted and revised the manuscript	created the figures and tables, drafted and revised the manuscript	Wrote the paper	Visualization|Writing - Original Draft|Writing - Review & Editing	YES
1891440	17593964	FM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1891440	17593964	FM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1891440	17593964	FM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1891440	17593964	GL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1891440	17593964	GL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1891440	17593964	GL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1891440	17593964	GL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1891440	17593964	GL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1891440	17593964	GO	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1891440	17593964	RL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1891440	17593964	SZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1891440	17593964	SZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1891440	17593964	SZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1891440	17593964	SZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3995322	24636198	NL	2	conceived and designed the study and prepared the manuscript	conceived and designed the study and prepared the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
3995322	24636198	PP	2	assisted the experimental work	assisted the experimental work	Performed the experiments	Investigation	YES
3995322	24636198	PW	2	provided medical coverage throughout the experiment	provided medical coverage throughout the experiment	-	-	NO
3995322	24636198	TR	2	carried out all the experimental work and statistical analysis and helped to draft the manuscript	carried out all the experimental work and statistical analysis and helped to draft the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3995322	24636198	YK	2	assisted the experimental work	assisted the experimental work	Performed the experiments	Investigation	YES
5723653	29270181	All authors	2	contributed to the interpretation and discussion of the results	contributed to the interpretation and discussion of the results	Analyzed the data	Formal analysis	YES
5723653	29270181	CDC	2	oversaw the greenhouse trial, assisted with the laboratory analyses, collected and analyzed the data, and wrote the first draft of the manuscript	oversaw the greenhouse trial, assisted with the laboratory analyses, collected and analyzed the data, and wrote the first draft of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Supervision|Writing - Original Draft	YES
5723653	29270181	GB	2	performed the hplc analysis and assisted with analysis of the statistical data	performed the hplc analysis and assisted with analysis of the statistical data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5723653	29270181	GBC	2	performed all the enzymatic and biological assays, and also collected and analyzed the data, carried out the literature research and improved the manuscript content	performed all the enzymatic and biological assays, and also collected and analyzed the data, carried out the literature research and improved the manuscript content	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
5723653	29270181	LS	2	helped revise the text	helped revise the text	Wrote the paper	Writing - Review & Editing	YES
5723653	29270181	PC	2	helped design the experiment, analyzed the data and improved the manuscript content	helped design the experiment, analyzed the data and improved the manuscript content	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Review & Editing	YES
5723653	29270181	TV	2	conceived the research idea, and corrected and arranged the final version of this work	conceived the research idea, and corrected and arranged the final version of this work	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5594591	28893204	YJ	2	supervised the project	supervised the project	-	Supervision	YES
3835882	24298212	A. E. Asfour	2	contributed equally to the work	contributed equally to the work	-	-	NO
4004506	24782684	All authors	2	contributed equally to this work	contributed equally to this work	-	-	NO
4414498	25923663	DEG	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414498	25923663	DEG	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414498	25923663	EKS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414498	25923663	EKS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414498	25923663	JLB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414498	25923663	JLB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414498	25923663	JLB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414498	25923663	JLB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414498	25923663	KKG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414498	25923663	KKG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414498	25923663	KKG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414498	25923663	KKG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414498	25923663	SWN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414498	25923663	SWN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414498	25923663	SWN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414498	25923663	SWN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414498	25923663	SWN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6020088	29943161	AE	2	performed the visual scan analysis and edited the manuscript	performed the visual scan analysis and edited the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Investigation|Visualization|Writing - Review & Editing	YES
6020088	29943161	AGL	2	designed the study, analysed the results and edited the manuscript	designed the study, analysed the results and edited the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
6020088	29943161	All authors	2	reviewed and agreed to the manuscript content	reviewed and agreed to the manuscript content	Wrote the paper	Writing - Review & Editing	YES
6020088	29943161	CEB	2	designed the study, analysed the results and edited the manuscript	designed the study, analysed the results and edited the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
6020088	29943161	FT	2	were involved in study design, patient recruitment and edited the manuscript	were involved in study design, patient recruitment and edited the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
6020088	29943161	GW	2	designed the study, analysed the results and edited the manuscript	designed the study, analysed the results and edited the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
6020088	29943161	IK	2	designed the technique, created the program, analysed the results and edited the manuscript	designed the technique, created the program, analysed the results and edited the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
6020088	29943161	JMW	2	designed the technique, created the program, analysed the results and edited the manuscript	designed the technique, created the program, analysed the results and edited the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
6020088	29943161	JW	2	designed the study, analysed the results and edited the manuscript	designed the study, analysed the results and edited the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
6020088	29943161	KR	2	designed the study, analysed the results and edited the manuscript	designed the study, analysed the results and edited the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
6020088	29943161	LEV	2	designed the study, analysed the results and edited the manuscript	designed the study, analysed the results and edited the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
6020088	29943161	MK	2	were involved in study design, patient recruitment and edited the manuscript	were involved in study design, patient recruitment and edited the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
6020088	29943161	PA	2	performed the visual scan analysis and edited the manuscript	performed the visual scan analysis and edited the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Investigation|Visualization|Writing - Review & Editing	YES
6020088	29943161	PD	2	designed the technique, created the program, analysed the results and edited the manuscript	designed the technique, created the program, analysed the results and edited the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
6020088	29943161	RJW	2	were involved in study design, patient recruitment and edited the manuscript	were involved in study design, patient recruitment and edited the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
6020088	29943161	RYC	2	designed the study, analysed the results and edited the manuscript	designed the study, analysed the results and edited the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
6020088	29943161	SG-R	2	performed the visual scan analysis and edited the manuscript	performed the visual scan analysis and edited the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Investigation|Visualization|Writing - Review & Editing	YES
6020088	29943161	STM	2	managed the patient recruitment, follow-up and sample collection	managed the patient recruitment, follow-up and sample collection	Performed the experiments	Investigation	YES
1891442	17593961	PS	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4012529	24855458	All authors	2	contributed to drafting of the manuscript	contributed to drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
4012529	24855458	CFC	2	developed the study design, data collection, statistical analysis, and all sport drink tested	developed the study design, data collection, statistical analysis, and all sport drink tested	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
4012529	24855458	CLL	2	developed the study design, data collection, statistical analysis, and all sport drink tested	developed the study design, data collection, statistical analysis, and all sport drink tested	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
4012529	24855458	HWH	2	contributed to the data collection and analysis	contributed to the data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4012529	24855458	JCL	2	was in charge of participant recruitment and management	was in charge of participant recruitment and management	Performed the experiments	Investigation	YES
4012529	24855458	TA	2	helped draft the manuscript	helped draft the manuscript	Wrote the paper	Writing - Original Draft	YES
4012529	24855458	WDC	2	provided consultation	provided consultation	-	-	NO
5594592	28893188	HBH	2	conceived, coordinated, and designed the study	conceived, coordinated, and designed the study	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
5594592	28893188	WW	2	were responsible for sequencing	were responsible for sequencing	Performed the experiments	Investigation	YES
5594592	28893188	XHZ	2	conceived, coordinated, and designed the study|were responsible for sequencing|performed experiments and data analyses|drafted the manuscript	conceived, coordinated, and designed the study	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
5594592	28893188	XHZ	2	conceived, coordinated, and designed the study|were responsible for sequencing|performed experiments and data analyses|drafted the manuscript	were responsible for sequencing	Performed the experiments	Investigation	YES
5594592	28893188	XHZ	2	conceived, coordinated, and designed the study|were responsible for sequencing|performed experiments and data analyses|drafted the manuscript	performed experiments and data analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5594592	28893188	XHZ	2	conceived, coordinated, and designed the study|were responsible for sequencing|performed experiments and data analyses|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5594592	28893188	XMS	2	conceived, coordinated, and designed the study|were responsible for sequencing|performed experiments and data analyses|drafted the manuscript	conceived, coordinated, and designed the study	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
5594592	28893188	XMS	2	conceived, coordinated, and designed the study|were responsible for sequencing|performed experiments and data analyses|drafted the manuscript	were responsible for sequencing	Performed the experiments	Investigation	YES
5594592	28893188	XMS	2	conceived, coordinated, and designed the study|were responsible for sequencing|performed experiments and data analyses|drafted the manuscript	performed experiments and data analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5594592	28893188	XMS	2	conceived, coordinated, and designed the study|were responsible for sequencing|performed experiments and data analyses|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5594592	28893188	XQH	2	conceived, coordinated, and designed the study	conceived, coordinated, and designed the study	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
5594592	28893188	ZW	2	performed experiments and data analyses	performed experiments and data analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5723656	29270183	All authors	2	wrote and edited the manuscript	wrote and edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5723656	29270183	CW	2	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5723656	29270183	DL	2	performed the experimental work	performed the experimental work	Performed the experiments	Investigation	YES
5723656	29270183	GP	2	supervised the research and manuscript preparation	supervised the research and manuscript preparation	Wrote the paper	Supervision|Writing - Original Draft	YES
5723656	29270183	XS	2	designed the experiments|performed the experimental work|performed the data analysis	designed the experiments	Conceived and designed the experiments	Methodology	YES
5723656	29270183	XS	2	designed the experiments|performed the experimental work|performed the data analysis	performed the experimental work	Performed the experiments	Investigation	YES
5723656	29270183	XS	2	designed the experiments|performed the experimental work|performed the data analysis	performed the data analysis	Analyzed the data	Formal analysis	YES
6049522	30061998	All authors	2	read, provided feedback on, and approved the manuscript	read, provided feedback on, and approved the manuscript	-	-	NO
6049522	30061998	C.A.	2	designed the experiments and analyzed the data|interpreted data|primarily wrote the manuscript	designed the experiments and analyzed the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
6049522	30061998	C.A.	2	designed the experiments and analyzed the data|interpreted data|primarily wrote the manuscript	interpreted data	Analyzed the data	Formal analysis	YES
6049522	30061998	C.A.	2	designed the experiments and analyzed the data|interpreted data|primarily wrote the manuscript	primarily wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6049522	30061998	M.F.K.	2	interpreted data	interpreted data	Analyzed the data	Formal analysis	YES
6049522	30061998	M.J.C.	2	carried out the cryo-tem experiment	carried out the cryo-tem experiment	Performed the experiments	Investigation	YES
6049522	30061998	S.R.	2	designed the experiments and analyzed the data|interpreted data|primarily wrote the manuscript	designed the experiments and analyzed the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
6049522	30061998	S.R.	2	designed the experiments and analyzed the data|interpreted data|primarily wrote the manuscript	interpreted data	Analyzed the data	Formal analysis	YES
6049522	30061998	S.R.	2	designed the experiments and analyzed the data|interpreted data|primarily wrote the manuscript	primarily wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6049522	30061998	T.R.	2	designed the experiments and analyzed the data|interpreted data|primarily wrote the manuscript	designed the experiments and analyzed the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
6049522	30061998	T.R.	2	designed the experiments and analyzed the data|interpreted data|primarily wrote the manuscript	interpreted data	Analyzed the data	Formal analysis	YES
6049522	30061998	T.R.	2	designed the experiments and analyzed the data|interpreted data|primarily wrote the manuscript	primarily wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4015534	24152940	GL	7	dissertation guidance, interpretation of the data and and drafted the manuscript	dissertation guidance, interpretation of the data and and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Supervision|Writing - Original Draft	YES
4015534	24152940	LZ	7	elisa assays assistance and biochemical assays	elisa assays assistance and biochemical assays	Performed the experiments	Investigation	YES
4015534	24152940	XZ	7	animal training assistance	animal training assistance	-	-	NO
4015534	24152940	YL	7	molecular biology assays	molecular biology assays	Performed the experiments	Investigation	YES
4015534	24152940	YW	7	paper revise	paper revise	Wrote the paper	Writing - Review & Editing	YES
4015534	24152940	ZZ	7	randomization of the protocol training of animals, literature review	randomization of the protocol training of animals, literature review	Conceived and designed the experiments	Formal analysis|Methodology	YES
6029989	29971587	CF	2	performed the statistical analyses and helped to draft and revise the manuscript	performed the statistical analyses and helped to draft and revise the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
6029989	29971587	CHL	2	participated in the statistical analysis, image processing, and writing of the manuscript	participated in the statistical analysis, image processing, and writing of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Visualization|Writing - Original Draft	YES
6029989	29971587	CZ	2	conceived the study and participated in its design and coordination	conceived the study and participated in its design and coordination	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
6029989	29971587	EB	2	participated in the data collection and coordination of the study	participated in the data collection and coordination of the study	Performed the experiments	Investigation|Project administration	YES
6029989	29971587	ER	2	participated in the design, data collection, and coordination of the study and helped to draft and revise the manuscript	participated in the design, data collection, and coordination of the study and helped to draft and revise the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Project administration|Writing - Original Draft|Writing - Review & Editing	YES
6029989	29971587	GS	2	conceived the study and participated in the design and coordination of the study	conceived the study and participated in the design and coordination of the study	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
6029989	29971587	HK	2	participated in the design and coordination of the study	participated in the design and coordination of the study	Conceived and designed the experiments	Methodology|Project administration	YES
6029989	29971587	IH	2	helped summarize the results, helped write the first draft, and critically revised the manuscript	helped summarize the results, helped write the first draft, and critically revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6029989	29971587	LN	2	participated in the data collection and coordination of the study	participated in the data collection and coordination of the study	Performed the experiments	Investigation|Project administration	YES
6029989	29971587	MF	2	participated in the design and data collection and helped to draft and revise the manuscript	participated in the design and data collection and helped to draft and revise the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
6029989	29971587	MN	2	participated in the data collection and coordination of the study	participated in the data collection and coordination of the study	Performed the experiments	Investigation|Project administration	YES
6029989	29971587	PY	2	participated in the data collection and coordination of the study	participated in the data collection and coordination of the study	Performed the experiments	Investigation|Project administration	YES
6029989	29971587	PZF	2	performed the kinetic modeling and image processing and helped to draft and revise the manuscript	performed the kinetic modeling and image processing and helped to draft and revise the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Investigation|Methodology|Visualization|Writing - Original Draft|Writing - Review & Editing	YES
6029989	29971587	RI	2	conceived the study and participated in its design and coordination	conceived the study and participated in its design and coordination	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
6029989	29971587	RMV	2	participated in the design, data collection, and coordination of the study	participated in the design, data collection, and coordination of the study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Project administration	YES
6029989	29971587	WD	2	participated in the design and coordination of the study	participated in the design and coordination of the study	Conceived and designed the experiments	Methodology|Project administration	YES
4414499	25923706	HW	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414499	25923706	HW	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414499	25923706	HW	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414499	25923706	LS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414499	25923706	LS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414499	25923706	LS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414499	25923706	WT	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414499	25923706	WT	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1892799	17593965	BA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1892799	17593965	BA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1892799	17593965	BA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1892799	17593965	HB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1892799	17593965	HB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1892799	17593965	HB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1892799	17593965	JS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1892799	17593965	JS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1892799	17593965	JS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1892799	17593965	ML	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1892799	17593965	ML	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5723670	29270189	HY	2	designed experiments|performed the experiments and analyzed the data|wrote the manuscript	designed experiments	Conceived and designed the experiments	Methodology	YES
5723670	29270189	HY	2	designed experiments|performed the experiments and analyzed the data|wrote the manuscript	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5723670	29270189	HY	2	designed experiments|performed the experiments and analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5723670	29270189	MH	2	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5723670	29270189	MK	2	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5723670	29270189	MN	2	designed experiments|performed the experiments and analyzed the data|wrote the manuscript	designed experiments	Conceived and designed the experiments	Methodology	YES
5723670	29270189	MN	2	designed experiments|performed the experiments and analyzed the data|wrote the manuscript	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5723670	29270189	MN	2	designed experiments|performed the experiments and analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5723670	29270189	RK	2	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5723670	29270189	TM	2	designed experiments|performed the experiments and analyzed the data|wrote the manuscript	designed experiments	Conceived and designed the experiments	Methodology	YES
5723670	29270189	TM	2	designed experiments|performed the experiments and analyzed the data|wrote the manuscript	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5723670	29270189	TM	2	designed experiments|performed the experiments and analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5723670	29270189	TY	2	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5723670	29270189	YF	2	performed the experiments and analyzed the data|wrote the manuscript	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5723670	29270189	YF	2	performed the experiments and analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5723670	29270189	YN	2	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4609364	26504800	Chi-Jen Chung	2	contributed equally to this work	contributed equally to this work	-	-	NO
4609364	26504800	Hsi-Kai Tsou	2	contributed equally to this work	contributed equally to this work	-	-	NO
4015629	24160307	KS	2	participated in the design of the study	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
4015629	24160307	MT	2	participated in the design of the study, carried out the experiment and drafted the manuscript	participated in the design of the study, carried out the experiment and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
4015629	24160307	TT	2	performed the coordination and data analyses of the study, and helped to draft the manuscript	performed the coordination and data analyses of the study, and helped to draft the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Project administration|Writing - Original Draft	YES
4015629	24160307	TU	2	conceived of the study and participated in its design	conceived of the study and participated in its design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4015629	24160307	YT	2	participated in data arrangement	participated in data arrangement	-	-	NO
5594617	28893194	MF	2	carried out lab and field work and processed the raw data, with|with critical contributions by all authors	carried out lab and field work and processed the raw data, with	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5594617	28893194	MF	2	carried out lab and field work and processed the raw data, with|with critical contributions by all authors	with critical contributions by all authors	-	-	NO
5594617	28893194	MH	2	with critical contributions by all authors	with critical contributions by all authors	-	-	NO
5594617	28893194	SG	2	helped mf carried out lab and field work and processed the raw data, with	helped mf carried out lab and field work and processed the raw data, with	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
6029992	29971556	AB	2	initiated and designed this study, provided study coordination, and was involved in the interpretation of data	initiated and designed this study, provided study coordination, and was involved in the interpretation of data	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Methodology|Project administration|Resources	YES
6029992	29971556	BK	2	were involved in the drafting, reviewing, and revising the manuscript	were involved in the drafting, reviewing, and revising the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6029992	29971556	FV	2	contributed in the analysis, interpretation of data, and reviewing of the manuscript	contributed in the analysis, interpretation of data, and reviewing of the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
6029992	29971556	GK	2	contributed in the analysis, interpretation of data, and reviewing of the manuscript	contributed in the analysis, interpretation of data, and reviewing of the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
6029992	29971556	LvK	2	was responsible for data gathering and analysis and interpretation of data and performed the statistical analysis	was responsible for data gathering and analysis and interpretation of data and performed the statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6029992	29971556	ML	2	were involved in the drafting, reviewing, and revising the manuscript	were involved in the drafting, reviewing, and revising the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6029992	29971556	RdR	2	contributed in the analysis, interpretation of data, and reviewing of the manuscript	contributed in the analysis, interpretation of data, and reviewing of the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
4414500	25923525	ATG	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414500	25923525	ATG	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414500	25923525	CGE	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414500	25923525	CGE	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414500	25923525	CGE	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414500	25923525	JC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414500	25923525	JC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414500	25923525	JC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414500	25923525	JC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414500	25923525	WM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414500	25923525	WM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414500	25923525	WM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414500	25923525	WM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5723928	29270184	HF	7	contributed to the design of the work|analyzed the sequencing data	contributed to the design of the work	Conceived and designed the experiments	-	YES
5723928	29270184	HF	7	contributed to the design of the work|analyzed the sequencing data	analyzed the sequencing data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5723928	29270184	LH	7	contributed to the design of the work|finally approved the version to be published, and was accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	contributed to the design of the work	Conceived and designed the experiments	-	YES
5723928	29270184	LH	7	contributed to the design of the work|finally approved the version to be published, and was accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	finally approved the version to be published, and was accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	-	-	NO
5723928	29270184	MX	7	drafted the work or revised it critically for important intellectual content	drafted the work or revised it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5723928	29270184	TZ	7	analyzed the sequencing data	analyzed the sequencing data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5723928	29270184	XG	7	drafted the work or revised it critically for important intellectual content	drafted the work or revised it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5723928	29270184	XZ	7	detected the expression of mirnas and the corresponding target genes	detected the expression of mirnas and the corresponding target genes	Performed the experiments	Investigation	YES
1892800	17593977	HV	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1892800	17593977	JK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1892800	17593977	JK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1892800	17593977	JK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1892800	17593977	MP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1892800	17593977	MP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1892800	17593977	MP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1892800	17593977	MP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1892800	17593977	TM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4015808	24153020	ANS	2	contributed to the writing, data analyses and data interpretation that are a part of this manuscript	contributed to the writing, data analyses and data interpretation that are a part of this manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
4015808	24153020	FCL	2	contributed to the writing, data analyses and data interpretation that are a part of this manuscript	contributed to the writing, data analyses and data interpretation that are a part of this manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
4015808	24153020	JKU	2	contributed to the writing, data analyses and data interpretation that are a part of this manuscript	contributed to the writing, data analyses and data interpretation that are a part of this manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
4015808	24153020	JPL	2	contributed to the writing, data analyses and data interpretation that are a part of this manuscript	contributed to the writing, data analyses and data interpretation that are a part of this manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
4015808	24153020	JPM	2	contributed to the writing, data analyses and data interpretation that are a part of this manuscript	contributed to the writing, data analyses and data interpretation that are a part of this manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
4015808	24153020	MNP	2	contributed to the writing, data analyses and data interpretation that are a part of this manuscript	contributed to the writing, data analyses and data interpretation that are a part of this manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
4015808	24153020	ZMS	2	contributed to the writing, data analyses and data interpretation that are a part of this manuscript	contributed to the writing, data analyses and data interpretation that are a part of this manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
4916078	27325348	All	2	participants gave informed consent before participation in the study	participants gave informed consent before participation in the study	-	-	NO
4916078	27325348	All authors	2	critically revised the manuscript|read and approved the final manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4916078	27325348	All authors	2	critically revised the manuscript|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4916078	27325348	CF	2	patient selection and blood collection	patient selection and blood collection	Performed the experiments	Investigation	YES
4916078	27325348	JHL	2	conceived the work, supervised all the experiments and wrote the manuscript	conceived the work, supervised all the experiments and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Supervision|Writing - Original Draft	YES
4916078	27325348	JRF	2	performed protein expression, purification and immunoblot experiments, and elisa experiments	performed protein expression, purification and immunoblot experiments, and elisa experiments	Performed the experiments	Investigation	YES
4916078	27325348	MAR	2	performed neutrophil experiments and contributed to the writing of the manuscript	performed neutrophil experiments and contributed to the writing of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4916078	27325348	MM	2	performed protein expression, purification and immunoblot experiments, and elisa experiments|performed neutrophil experiments and contributed to the writing of the manuscript	performed protein expression, purification and immunoblot experiments, and elisa experiments	Performed the experiments	Investigation	YES
4916078	27325348	MM	2	performed protein expression, purification and immunoblot experiments, and elisa experiments|performed neutrophil experiments and contributed to the writing of the manuscript	performed neutrophil experiments and contributed to the writing of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4916078	27325348	P. The	2	authors declare that they have no competing interests	authors declare that they have no competing interests	-	-	NO
4916078	27325348	REE-H	2	performed neutrophil experiments and contributed to the writing of the manuscript	performed neutrophil experiments and contributed to the writing of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4916078	27325348	SAS	2	conceived the work, supervised all the experiments and wrote the manuscript|performed the cloning experiments and bioinformatics analyses|performed protein expression, purification and immunoblot experiments, and elisa experiments	conceived the work, supervised all the experiments and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Supervision|Writing - Original Draft	YES
4916078	27325348	SAS	2	conceived the work, supervised all the experiments and wrote the manuscript|performed the cloning experiments and bioinformatics analyses|performed protein expression, purification and immunoblot experiments, and elisa experiments	performed the cloning experiments and bioinformatics analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4916078	27325348	SAS	2	conceived the work, supervised all the experiments and wrote the manuscript|performed the cloning experiments and bioinformatics analyses|performed protein expression, purification and immunoblot experiments, and elisa experiments	performed protein expression, purification and immunoblot experiments, and elisa experiments	Performed the experiments	Investigation	YES
4916078	27325348	SN	2	performed neutrophil experiments and contributed to the writing of the manuscript	performed neutrophil experiments and contributed to the writing of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4916078	27325348	TP	2	performed protein expression, purification and immunoblot experiments, and elisa experiments	performed protein expression, purification and immunoblot experiments, and elisa experiments	Performed the experiments	Investigation	YES
4022420	24834017	AE	2	was involved in the execution of the measurements	was involved in the execution of the measurements	Performed the experiments	Investigation	YES
4022420	24834017	BF	2	was involved in the execution of the measurements	was involved in the execution of the measurements	Performed the experiments	Investigation	YES
4022420	24834017	CP	2	provided assistance in the study design, statistical analysis and editing of the manuscript	provided assistance in the study design, statistical analysis and editing of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
4022420	24834017	JA	2	was responsible for the study design, the statistical analysis and the writing of the manuscript	was responsible for the study design, the statistical analysis and the writing of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4022420	24834017	TS	2	provided assistance in the study design, statistical analysis and editing of the manuscript	provided assistance in the study design, statistical analysis and editing of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
6029994	29971517	BFH	2	contributed to the interpretation of data and results	contributed to the interpretation of data and results	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6029994	29971517	DA	2	contributed to revising the manuscript	contributed to revising the manuscript	Wrote the paper	Writing - Review & Editing	YES
6029994	29971517	HBL	2	contributed to the acquisition of data	contributed to the acquisition of data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
6029994	29971517	HS	2	contributed to the analysis and interpretation of data and drafted the manuscript	contributed to the analysis and interpretation of data and drafted the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
6029994	29971517	IL	2	contributed to the acquisition of data	contributed to the acquisition of data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
6029994	29971517	KE	2	contributed to the interpretation of data and results	contributed to the interpretation of data and results	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6029994	29971517	KT	2	contributed to revising the manuscript	contributed to revising the manuscript	Wrote the paper	Writing - Review & Editing	YES
6029994	29971517	LM	2	contributed to the acquisition of data	contributed to the acquisition of data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
6029994	29971517	SA	2	contributed to revising the manuscript	contributed to revising the manuscript	Wrote the paper	Writing - Review & Editing	YES
6029994	29971517	SO	2	contributed to revising the manuscript	contributed to revising the manuscript	Wrote the paper	Writing - Review & Editing	YES
5723933	29270180	DW	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5723933	29270180	NNW	PLoS52	conceived and designed the study, supervised the experiments, and compiled and finalized the article|analyzed the data|drafted and revised the manuscript	conceived and designed the study, supervised the experiments, and compiled and finalized the article	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Supervision|Writing - Review & Editing	YES
5723933	29270180	NNW	PLoS52	conceived and designed the study, supervised the experiments, and compiled and finalized the article|analyzed the data|drafted and revised the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5723933	29270180	NNW	PLoS52	conceived and designed the study, supervised the experiments, and compiled and finalized the article|analyzed the data|drafted and revised the manuscript	drafted and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5723933	29270180	YM	PLoS52	analyzed the data|drafted and wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5723933	29270180	YM	PLoS52	analyzed the data|drafted and wrote the manuscript	drafted and wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4414501	25923439	BCY	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414501	25923439	BCY	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414501	25923439	DHS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414501	25923439	DHS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414501	25923439	DHS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414501	25923439	DHS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414501	25923439	GYG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414501	25923439	GYG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414501	25923439	GYG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414501	25923439	JHL	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414501	25923439	JHL	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414501	25923439	JYC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414501	25923439	JYC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414501	25923439	JYC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414501	25923439	KCK	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414501	25923439	KCK	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414501	25923439	MSC	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414501	25923439	MSC	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414501	25923439	SWP	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414501	25923439	SWP	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414501	25923439	YHP	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414501	25923439	YHP	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5596466	28899353	B.T.	2	handled animals for study use, performed dissections to generate samples, and contributed to drafts of the initial manuscript	handled animals for study use, performed dissections to generate samples, and contributed to drafts of the initial manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5596466	28899353	B.Z.	2	contributed computational tools for data processing	contributed computational tools for data processing	Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Formal analysis|Resources	YES
5596466	28899353	C.G.	2	contributed to data analysis and quality control	contributed to data analysis and quality control	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Validation	YES
5596466	28899353	D.L.	2	contributed computational tools for data processing	contributed computational tools for data processing	Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Formal analysis|Resources	YES
5596466	28899353	H.J.L.	2	contributed to data analysis and quality control	contributed to data analysis and quality control	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Validation	YES
5596466	28899353	H.S.J.	2	contributed to data analysis and quality control	contributed to data analysis and quality control	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Validation	YES
5596466	28899353	J.A.	2	handled animals for study use, performed dissections to generate samples, and contributed to drafts of the initial manuscript	handled animals for study use, performed dissections to generate samples, and contributed to drafts of the initial manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5596466	28899353	J.Z.	2	conceived and designed the study|performed data analysis|performed experiments and generated sequencing libraries|wrote the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5596466	28899353	J.Z.	2	conceived and designed the study|performed data analysis|performed experiments and generated sequencing libraries|wrote the manuscript	performed data analysis	Analyzed the data	Formal analysis	YES
5596466	28899353	J.Z.	2	conceived and designed the study|performed data analysis|performed experiments and generated sequencing libraries|wrote the manuscript	performed experiments and generated sequencing libraries	Performed the experiments	Investigation	YES
5596466	28899353	J.Z.	2	conceived and designed the study|performed data analysis|performed experiments and generated sequencing libraries|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5596466	28899353	M.N.K.C.	2	contributed to data analysis and quality control	contributed to data analysis and quality control	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Validation	YES
5596466	28899353	N.B.R.	2	contributed to data analysis and quality control	contributed to data analysis and quality control	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Validation	YES
5596466	28899353	R.F.L.	2	contributed to data analysis and quality control	contributed to data analysis and quality control	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Validation	YES
5596466	28899353	R.L.S.	2	performed data analysis|wrote the manuscript	performed data analysis	Analyzed the data	Formal analysis	YES
5596466	28899353	R.L.S.	2	performed data analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5596466	28899353	T.J.C.	2	contributed to data analysis and quality control	contributed to data analysis and quality control	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Validation	YES
5596466	28899353	T.W.	2	conceived and designed the study|performed data analysis|wrote the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5596466	28899353	T.W.	2	conceived and designed the study|performed data analysis|wrote the manuscript	performed data analysis	Analyzed the data	Formal analysis	YES
5596466	28899353	T.W.	2	conceived and designed the study|performed data analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5596466	28899353	X.X.	2	performed experiments and generated sequencing libraries	performed experiments and generated sequencing libraries	Performed the experiments	Investigation	YES
4929112	27363997	AC	2	has contributed with planning and design of research work as well as interpretation of data	has contributed with planning and design of research work as well as interpretation of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Methodology|Resources	YES
4929112	27363997	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4929112	27363997	EFL	2	has contributed with planning and implementation of the research work as well as interpretation of data and article preparation	has contributed with planning and implementation of the research work as well as interpretation of data and article preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Methodology|Resources	YES
4929112	27363997	MJT	2	has contributed with planning and implementation of research work as well as revising the article critically	has contributed with planning and implementation of research work as well as revising the article critically	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
4929112	27363997	SF	2	has contributed with planning and implementation of the research work as well as interpretation of data and article preparation	has contributed with planning and implementation of the research work as well as interpretation of data and article preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Methodology|Resources	YES
4029397	24325803	ACS	2	participated in the realization of biochemical analysis	participated in the realization of biochemical analysis	Performed the experiments	Investigation	YES
4029397	24325803	CR	2	participated in the realization of biochemical analysis	participated in the realization of biochemical analysis	Performed the experiments	Investigation	YES
4029397	24325803	LPM	2	held the writing of the manuscript	held the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
4029397	24325803	MARM	2	participated in the realization of biochemical analysis	participated in the realization of biochemical analysis	Performed the experiments	Investigation	YES
4029397	24325803	MBA	2	was responsible for the study design, execution of biochemical analysis, statistical analysis and writing of the manuscript	was responsible for the study design, execution of biochemical analysis, statistical analysis and writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4029397	24325803	MCJ	2	participated in the realization of biochemical analysis	participated in the realization of biochemical analysis	Performed the experiments	Investigation	YES
4029397	24325803	RAD	2	participated in the realization of biochemical analysis	participated in the realization of biochemical analysis	Performed the experiments	Investigation	YES
4029397	24325803	RCVJ	2	participated in the realization of biochemical analysis	participated in the realization of biochemical analysis	Performed the experiments	Investigation	YES
1892801	17593967	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1892801	17593967	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1892801	17593967	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1892801	17593967	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1892801	17593967	JY	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1892801	17593967	ML	PLoS5	Conceived and designed the experiments|Analyzed the data|Revised the paper before submission	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1892801	17593967	ML	PLoS5	Conceived and designed the experiments|Analyzed the data|Revised the paper before submission	Analyzed the data	Analyzed the data	Formal analysis	YES
1892801	17593967	ML	PLoS5	Conceived and designed the experiments|Analyzed the data|Revised the paper before submission	Revised the paper before submission	Wrote the paper	Writing - Review & Editing	YES
1892801	17593967	WS	PLoS5	Contributed reagents/materials/analysis tools|Revised the paper before submission	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1892801	17593967	WS	PLoS5	Contributed reagents/materials/analysis tools|Revised the paper before submission	Revised the paper before submission	Wrote the paper	Writing - Review & Editing	YES
5724233	29270185	FG	PLoS52	performed the data analysis|revised the paper	performed the data analysis	Analyzed the data	Formal analysis	YES
5724233	29270185	FG	PLoS52	performed the data analysis|revised the paper	revised the paper	Wrote the paper	Writing - Review & Editing	YES
5724233	29270185	GR	PLoS52	revised the paper	revised the paper	Wrote the paper	Writing - Review & Editing	YES
5724233	29270185	JL	PLoS52	performed the experiments|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5724233	29270185	JL	PLoS52	performed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5724233	29270185	JR	PLoS52	revised the paper	revised the paper	Wrote the paper	Writing - Review & Editing	YES
5724233	29270185	RW	PLoS52	conceived and designed the experiments|performed the experiments|performed the data analysis|wrote the paper|revised the paper|secured the funds to support this research	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5724233	29270185	RW	PLoS52	conceived and designed the experiments|performed the experiments|performed the data analysis|wrote the paper|revised the paper|secured the funds to support this research	performed the experiments	Performed the experiments	Investigation	YES
5724233	29270185	RW	PLoS52	conceived and designed the experiments|performed the experiments|performed the data analysis|wrote the paper|revised the paper|secured the funds to support this research	performed the data analysis	Analyzed the data	Formal analysis	YES
5724233	29270185	RW	PLoS52	conceived and designed the experiments|performed the experiments|performed the data analysis|wrote the paper|revised the paper|secured the funds to support this research	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5724233	29270185	RW	PLoS52	conceived and designed the experiments|performed the experiments|performed the data analysis|wrote the paper|revised the paper|secured the funds to support this research	revised the paper	Wrote the paper	Writing - Review & Editing	YES
5724233	29270185	RW	PLoS52	conceived and designed the experiments|performed the experiments|performed the data analysis|wrote the paper|revised the paper|secured the funds to support this research	secured the funds to support this research	-	Funding acquisition	YES
5724233	29270185	XL	PLoS52	revised the paper	revised the paper	Wrote the paper	Writing - Review & Editing	YES
6031550	29974335	BC	PLoS52	designed the experiments|performed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
6031550	29974335	BC	PLoS52	designed the experiments|performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
6031550	29974335	JAE	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
6031550	29974335	JRG	PLoS52	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
6031550	29974335	PLD	PLoS52	designed the experiments|performed the experiments|analyzed the data|wrote the paper	designed the experiments	Conceived and designed the experiments	Methodology	YES
6031550	29974335	PLD	PLoS52	designed the experiments|performed the experiments|analyzed the data|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
6031550	29974335	PLD	PLoS52	designed the experiments|performed the experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
6031550	29974335	PLD	PLoS52	designed the experiments|performed the experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6031550	29974335	RJY	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6031550	29974335	SAJ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
6031550	29974335	SK	PLoS52	designed the experiments|performed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
6031550	29974335	SK	PLoS52	designed the experiments|performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
6031550	29974335	TR	PLoS52	designed the experiments|wrote the paper	designed the experiments	Conceived and designed the experiments	Methodology	YES
6031550	29974335	TR	PLoS52	designed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6031550	29974335	WW	PLoS52	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
4930434	27368914	JO	1	Experiment planning and design|Pigment production and analysis|Purification of pigment|Paper construction	Experiment planning and design	Conceived and designed the experiments	Methodology	YES
4930434	27368914	JO	1	Experiment planning and design|Pigment production and analysis|Purification of pigment|Paper construction	Pigment production and analysis	-	-	NO
4930434	27368914	JO	1	Experiment planning and design|Pigment production and analysis|Purification of pigment|Paper construction	Purification of pigment	Performed the experiments	Investigation	YES
4930434	27368914	JO	1	Experiment planning and design|Pigment production and analysis|Purification of pigment|Paper construction	Paper construction	Performed the experiments	Investigation	YES
4930434	27368914	RK	1	Experiment planning and design|Pigment production and analysis|Paper construction	Experiment planning and design	Conceived and designed the experiments	Methodology	YES
4930434	27368914	RK	1	Experiment planning and design|Pigment production and analysis|Paper construction	Pigment production and analysis	-	-	NO
4930434	27368914	RK	1	Experiment planning and design|Pigment production and analysis|Paper construction	Paper construction	Performed the experiments	Investigation	YES
4930434	27368914	TA	1	Pigment production and analysis	Pigment production and analysis	-	-	NO
4930434	27368914	TK	1	Experiment planning and design|Paper construction	Experiment planning and design	Conceived and designed the experiments	Methodology	YES
4930434	27368914	TK	1	Experiment planning and design|Paper construction	Paper construction	Performed the experiments	Investigation	YES
4930434	27368914	TW	1	Experiment planning and design|Paper construction	Experiment planning and design	Conceived and designed the experiments	Methodology	YES
4930434	27368914	TW	1	Experiment planning and design|Paper construction	Paper construction	Performed the experiments	Investigation	YES
4414503	25923531	FFG	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Collected the isolates	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414503	25923531	FFG	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Collected the isolates	Performed the experiments	Performed the experiments	Investigation	YES
4414503	25923531	FFG	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Collected the isolates	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414503	25923531	FFG	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Collected the isolates	Collected the isolates	Performed the experiments	Investigation	YES
4414503	25923531	HHY	PLoS5	Collected the isolates	Collected the isolates	Performed the experiments	Investigation	YES
4414503	25923531	LZH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414503	25923531	LZH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414503	25923531	LZH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414503	25923531	QH	PLoS5	Collected the isolates	Collected the isolates	Performed the experiments	Investigation	YES
4414503	25923531	XKG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4414503	25923531	XKG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414503	25923531	YQZ	PLoS5	Collected the isolates	Collected the isolates	Performed the experiments	Investigation	YES
4414503	25923531	YXN	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4414503	25923531	YXN	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4031978	24860277	BX	2	were responsible for biochemical work, dietary record and calculation, data collection/entry, and assistance with manuscript preparation	were responsible for biochemical work, dietary record and calculation, data collection/entry, and assistance with manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Formal analysis|Investigation|Writing - Original Draft	YES
4031978	24860277	CF	2	were responsible for biochemical work, dietary record and calculation, data collection/entry, and assistance with manuscript preparation	were responsible for biochemical work, dietary record and calculation, data collection/entry, and assistance with manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Formal analysis|Investigation|Writing - Original Draft	YES
4031978	24860277	COC	2	helped draft the manuscript	helped draft the manuscript	Wrote the paper	Writing - Original Draft	YES
4031978	24860277	GH	2	participated in formulating study design	participated in formulating study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4031978	24860277	HG	2	were responsible for biochemical work, dietary record and calculation, data collection/entry, and assistance with manuscript preparation	were responsible for biochemical work, dietary record and calculation, data collection/entry, and assistance with manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Formal analysis|Investigation|Writing - Original Draft	YES
4031978	24860277	JB	2	helped draft the manuscript	helped draft the manuscript	Wrote the paper	Writing - Original Draft	YES
4031978	24860277	JF	2	were responsible for biochemical work, dietary record and calculation, data collection/entry, and assistance with manuscript preparation	were responsible for biochemical work, dietary record and calculation, data collection/entry, and assistance with manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Formal analysis|Investigation|Writing - Original Draft	YES
4031978	24860277	JL	2	were responsible for biochemical work, dietary record and calculation, data collection/entry, and assistance with manuscript preparation	were responsible for biochemical work, dietary record and calculation, data collection/entry, and assistance with manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Formal analysis|Investigation|Writing - Original Draft	YES
4031978	24860277	JS	2	were responsible for biochemical work, dietary record and calculation, data collection/entry, and assistance with manuscript preparation	were responsible for biochemical work, dietary record and calculation, data collection/entry, and assistance with manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Formal analysis|Investigation|Writing - Original Draft	YES
4031978	24860277	KL	2	participated in formulating study design	participated in formulating study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4031978	24860277	LZ	2	were responsible for study design, data collection, statistical analysis, and manuscript preparation	were responsible for study design, data collection, statistical analysis, and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4031978	24860277	MY	2	were responsible for study design, data collection, statistical analysis, and manuscript preparation	were responsible for study design, data collection, statistical analysis, and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4031978	24860277	QW	2	were responsible for biochemical work, dietary record and calculation, data collection/entry, and assistance with manuscript preparation	were responsible for biochemical work, dietary record and calculation, data collection/entry, and assistance with manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Formal analysis|Investigation|Writing - Original Draft	YES
1892802	17593979	ES	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1892802	17593979	ES	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1892802	17593979	ES	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1892802	17593979	TG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1892802	17593979	TG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1892802	17593979	TG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1892802	17593979	TG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5596473	28899344	MA	2	contributed to the bioinformatics analysis	contributed to the bioinformatics analysis	-	Formal analysis	YES
5596473	28899344	NKV	2	conceived and directed the study|drafted the manuscript	conceived and directed the study	Conceived and designed the experiments	Conceptualization|Supervision	YES
5596473	28899344	NKV	2	conceived and directed the study|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5596473	28899344	PP	2	performed the dna extraction, assembled and annotated the genome|contributed to the bioinformatics analysis|drafted the manuscript	performed the dna extraction, assembled and annotated the genome	Performed the experiments	Investigation	YES
5596473	28899344	PP	2	performed the dna extraction, assembled and annotated the genome|contributed to the bioinformatics analysis|drafted the manuscript	contributed to the bioinformatics analysis	-	Formal analysis	YES
5596473	28899344	PP	2	performed the dna extraction, assembled and annotated the genome|contributed to the bioinformatics analysis|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
6045565	30006851	AH	2	provided input on the study design and manuscript review	provided input on the study design and manuscript review	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
6045565	30006851	BV	2	aided in the derivation of clinical parameters, study design and manuscript production	aided in the derivation of clinical parameters, study design and manuscript production	Conceived and designed the experiments	Methodology	YES
6045565	30006851	GM	2	aided in the database management and statistical analysis advice and aided in manuscript production	aided in the database management and statistical analysis advice and aided in manuscript production	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Software	YES
6045565	30006851	HL	2	led the study design, collected clinical parameters, performed data analysis and was the primary manuscript producer	led the study design, collected clinical parameters, performed data analysis and was the primary manuscript producer	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
6045565	30006851	IDD	2	helped in the study design, statistical analysis and manuscript preparation	helped in the study design, statistical analysis and manuscript preparation	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
6045565	30006851	MV	2	provided input on the study design and manuscript review	provided input on the study design and manuscript review	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
6045565	30006851	NR	2	provided input on the study design and manuscript review	provided input on the study design and manuscript review	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
6045565	30006851	PF	2	facilitated the overall study concept and design, validated lesion delineation, advised on data analysis techniques and aided in the manuscript preparation	facilitated the overall study concept and design, validated lesion delineation, advised on data analysis techniques and aided in the manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Validation|Writing - Original Draft	YES
6045565	30006851	TG	2	aided in the study design and manuscript production	aided in the study design and manuscript production	Conceived and designed the experiments	Methodology	YES
6050528	30079215	C.M.	2	conceived the research|carried out the experiments|wrote the manuscript	conceived the research	Conceived and designed the experiments	Conceptualization	YES
6050528	30079215	C.M.	2	conceived the research|carried out the experiments|wrote the manuscript	carried out the experiments	Performed the experiments	Investigation	YES
6050528	30079215	C.M.	2	conceived the research|carried out the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6050528	30079215	F.T.	2	conceived the research|carried out the experiments|wrote the manuscript	conceived the research	Conceived and designed the experiments	Conceptualization	YES
6050528	30079215	F.T.	2	conceived the research|carried out the experiments|wrote the manuscript	carried out the experiments	Performed the experiments	Investigation	YES
6050528	30079215	F.T.	2	conceived the research|carried out the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6050528	30079215	R.E.	2	conceived the research|directed the research|revised the manuscript	conceived the research	Conceived and designed the experiments	Conceptualization	YES
6050528	30079215	R.E.	2	conceived the research|directed the research|revised the manuscript	directed the research	-	Supervision	YES
6050528	30079215	R.E.	2	conceived the research|directed the research|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
6050528	30079215	all authors	2	commented on the work and the manuscript	commented on the work and the manuscript	-	-	NO
4932009	27376945	All authors	2	contributed to the design of the experiments|read and approved the final manuscript	contributed to the design of the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4932009	27376945	All authors	2	contributed to the design of the experiments|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4932009	27376945	Jose Antonio Echeverria	2	birzeit university	birzeit university	-	-	NO
4932009	27376945	LW	2	performed the experiments and drafted the manuscript	performed the experiments and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4033492	24864135	AAA	2	wrote the sections on nutrient timing and meal frequency	wrote the sections on nutrient timing and meal frequency	Wrote the paper	Writing - Original Draft	YES
4033492	24864135	ERH	2	developed the concept for this manuscript and wrote the sections on caloric intake, macronutrients, psychosocial issues and peak week	developed the concept for this manuscript and wrote the sections on caloric intake, macronutrients, psychosocial issues and peak week	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4033492	24864135	PJF	2	wrote the abstract, methods, limitations, and the section on dietary supplementation	wrote the abstract, methods, limitations, and the section on dietary supplementation	Performed the experiments|Wrote the paper	Writing - Original Draft	YES
1892803	17593969	AF	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1892803	17593969	AG	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1892803	17593969	AT	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1892803	17593969	DJ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1892803	17593969	MC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1892803	17593969	SH	PLoS5	Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1892803	17593969	SH	PLoS5	Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4609369	26504803	Feng Liu	2	contributed equally to this work	contributed equally to this work	-	-	NO
4609369	26504803	Shihua Wu	2	contributed equally to this work	contributed equally to this work	-	-	NO
4414504	25922936	AJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414504	25922936	AJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414504	25922936	AJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414504	25922936	AJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414504	25922936	AJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414504	25922936	AL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414504	25922936	AL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414504	25922936	AL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414504	25922936	AL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414504	25922936	AL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414504	25922936	AMM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414504	25922936	AMM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414504	25922936	AMM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414504	25922936	AMM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414504	25922936	AMM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414504	25922936	ARS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414504	25922936	ARS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414504	25922936	ARS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414504	25922936	ARS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414504	25922936	ARS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414504	25922936	ATS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414504	25922936	ATS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414504	25922936	ATS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414504	25922936	ATS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414504	25922936	ATS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414504	25922936	BKW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414504	25922936	BKW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414504	25922936	BKW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414504	25922936	BKW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414504	25922936	BKW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414504	25922936	ZZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414504	25922936	ZZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414504	25922936	ZZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414504	25922936	ZZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414504	25922936	ZZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1892804	17593970	BT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1892804	17593970	BT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1892804	17593970	BT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1892804	17593970	BT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1892804	17593970	BT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1892804	17593970	CB	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1892804	17593970	CB	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1892804	17593970	JH	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1892804	17593970	JH	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1892804	17593970	XB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1892804	17593970	XB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1892804	17593970	XB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5596481	28899413	ACF	2	carried out the genomic comparative analysis and wrote the manuscript|carried out the experimental work	carried out the genomic comparative analysis and wrote the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5596481	28899413	ACF	2	carried out the genomic comparative analysis and wrote the manuscript|carried out the experimental work	carried out the experimental work	Performed the experiments	Investigation	YES
5596481	28899413	MICS	2	conceived and planned the study, and revised the manuscript	conceived and planned the study, and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5596481	28899413	RD	2	carried out the genomic comparative analysis and wrote the manuscript|conceived and planned the study, and revised the manuscript	carried out the genomic comparative analysis and wrote the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5596481	28899413	RD	2	carried out the genomic comparative analysis and wrote the manuscript|conceived and planned the study, and revised the manuscript	conceived and planned the study, and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5596481	28899413	RT	2	conceived and planned the study, and revised the manuscript	conceived and planned the study, and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
4038365	24876828	JB	2	provided assistance in the editing of the manuscript	provided assistance in the editing of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4038365	24876828	KK	2	was involved in the execution of the measurements and the writing of the manuscript	was involved in the execution of the measurements and the writing of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4038365	24876828	KL	2	was responsible for the study design, the statistical analysis, execution of the measurements and the writing of the manuscript	was responsible for the study design, the statistical analysis, execution of the measurements and the writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
6047947	30014266	BF	2	prepared the solution for injection	prepared the solution for injection	Performed the experiments	Investigation	YES
6047947	30014266	F-BCPP	2	prepared the solution for injection	prepared the solution for injection	Performed the experiments	Investigation	YES
6047947	30014266	HO	2	performed animal experiments and data analysis	performed animal experiments and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6047947	30014266	HT	2	designed the study and drafted the manuscript	designed the study and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
6047947	30014266	OI	2	designed the study and drafted the manuscript	designed the study and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
6047947	30014266	TK	2	performed animal experiments and data analysis	performed animal experiments and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6047947	30014266	TS	2	designed the study and drafted the manuscript	designed the study and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4938812	27392493	A. Kondo	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
4938812	27392493	AK	2	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
4938812	27392493	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4938812	27392493	J. Ishii	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
4938812	27392493	JI	2	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
4938812	27392493	M. Kaishima	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
4938812	27392493	MK	2	conducted experiments	conducted experiments	Performed the experiments	Investigation	YES
4938812	27392493	N. Fukuda	2	declare that they are inventors on a pending patent using aspects of this work	declare that they are inventors on a pending patent using aspects of this work	-	-	NO
4938812	27392493	NF	2	designed the study|conducted experiments|analyzed data|co-wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
4938812	27392493	NF	2	designed the study|conducted experiments|analyzed data|co-wrote the manuscript	conducted experiments	Performed the experiments	Investigation	YES
4938812	27392493	NF	2	designed the study|conducted experiments|analyzed data|co-wrote the manuscript	analyzed data	Analyzed the data	Formal analysis	YES
4938812	27392493	NF	2	designed the study|conducted experiments|analyzed data|co-wrote the manuscript	co-wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4938812	27392493	S. Honda	2	declare that they are inventors on a pending patent using aspects of this work	declare that they are inventors on a pending patent using aspects of this work	-	-	NO
4938812	27392493	SH	2	analyzed data|co-wrote the manuscript	analyzed data	Analyzed the data	Formal analysis	YES
4938812	27392493	SH	2	analyzed data|co-wrote the manuscript	co-wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5725443	29270186	GL	2	prepared samples for ms|evaluated ms data|were responsible for interpreting the proteomic data|were responsible for writing the manuscript	prepared samples for ms	Performed the experiments	Investigation	YES
5725443	29270186	GL	2	prepared samples for ms|evaluated ms data|were responsible for interpreting the proteomic data|were responsible for writing the manuscript	evaluated ms data	-	-	NO
5725443	29270186	GL	2	prepared samples for ms|evaluated ms data|were responsible for interpreting the proteomic data|were responsible for writing the manuscript	were responsible for interpreting the proteomic data	Analyzed the data	Formal analysis	YES
5725443	29270186	GL	2	prepared samples for ms|evaluated ms data|were responsible for interpreting the proteomic data|were responsible for writing the manuscript	were responsible for writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5725443	29270186	II	2	performed statistical analyses|were responsible for interpreting the proteomic data|were responsible for writing the manuscript	performed statistical analyses	Analyzed the data	Formal analysis	YES
5725443	29270186	II	2	performed statistical analyses|were responsible for interpreting the proteomic data|were responsible for writing the manuscript	were responsible for interpreting the proteomic data	Analyzed the data	Formal analysis	YES
5725443	29270186	II	2	performed statistical analyses|were responsible for interpreting the proteomic data|were responsible for writing the manuscript	were responsible for writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5725443	29270186	JF	2	were responsible for interpreting the biological context	were responsible for interpreting the biological context	Analyzed the data	Formal analysis	YES
5725443	29270186	MF	2	were responsible for interpreting the biological context|were responsible for writing the manuscript	were responsible for interpreting the biological context	Analyzed the data	Formal analysis	YES
5725443	29270186	MF	2	were responsible for interpreting the biological context|were responsible for writing the manuscript	were responsible for writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5725443	29270186	SB	2	cultivated plants and isolated histones|were responsible for writing the manuscript	cultivated plants and isolated histones	Performed the experiments	Investigation	YES
5725443	29270186	SB	2	cultivated plants and isolated histones|were responsible for writing the manuscript	were responsible for writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5725443	29270186	ZZ	2	were responsible for interpreting the proteomic data|were responsible for writing the manuscript	were responsible for interpreting the proteomic data	Analyzed the data	Formal analysis	YES
5725443	29270186	ZZ	2	were responsible for interpreting the proteomic data|were responsible for writing the manuscript	were responsible for writing the manuscript	Wrote the paper	Writing - Original Draft	YES
4414505	25923700	DH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414505	25923700	DH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414505	25923700	DH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414505	25923700	DH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414505	25923700	RSW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414505	25923700	RSW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414505	25923700	RSW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414505	25923700	RSW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414505	25923700	RSW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414505	25923700	TP	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414505	25923700	TP	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414505	25923700	TP	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414505	25923700	TP	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4609370	26504797	Daqing Zhang	2	contributed equally to this work	contributed equally to this work	-	-	NO
4609370	26504797	Jianfeng Xiao	2	contributed equally to this work	contributed equally to this work	-	-	NO
4609370	26504797	Nannan Zhou	2	contributed equally to this work	contributed equally to this work	-	-	NO
1892805	17593972	CP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1892805	17593972	DC	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1892805	17593972	DC	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1892805	17593972	EO	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1892805	17593972	KS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1892805	17593972	MF	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1892805	17593972	MF	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1892805	17593972	MF	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5596863	28899357	GHM	2	participated in data analysis|performed the qpcr verification experiment|collected and prepared the experimental materials	participated in data analysis	Analyzed the data	Formal analysis	YES
5596863	28899357	GHM	2	participated in data analysis|performed the qpcr verification experiment|collected and prepared the experimental materials	performed the qpcr verification experiment	Performed the experiments	Investigation|Validation	YES
5596863	28899357	GHM	2	participated in data analysis|performed the qpcr verification experiment|collected and prepared the experimental materials	collected and prepared the experimental materials	Performed the experiments	Investigation	YES
5596863	28899357	LHS	2	participated in manuscript formatting and editing	participated in manuscript formatting and editing	Wrote the paper	Writing - Review & Editing	YES
5596863	28899357	RFL	2	contributed to the research design and reviewed the manuscript	contributed to the research design and reviewed the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Review & Editing	YES
5596863	28899357	YB	2	performed the qpcr verification experiment	performed the qpcr verification experiment	Performed the experiments	Investigation|Validation	YES
5596863	28899357	YD	2	collected and prepared the experimental materials	collected and prepared the experimental materials	Performed the experiments	Investigation	YES
5596863	28899357	ZPW	2	designed the research framework, carried out the experiments, performed the bioinformatics analyses, and drafted the manuscript	designed the research framework, carried out the experiments, performed the bioinformatics analyses, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
6047954	30014313	CHC	2	contributed to the patient selection and data acquisition|contributed to the critical revision of the manuscript	contributed to the patient selection and data acquisition	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
6047954	30014313	CHC	2	contributed to the patient selection and data acquisition|contributed to the critical revision of the manuscript	contributed to the critical revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
6047954	30014313	CHL	2	contributed to the patient selection and data acquisition|contributed to the critical revision of the manuscript	contributed to the patient selection and data acquisition	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
6047954	30014313	CHL	2	contributed to the patient selection and data acquisition|contributed to the critical revision of the manuscript	contributed to the critical revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
6047954	30014313	ITH	2	designed the study|contributed to the data analysis and interpretation|supervised the whole part of the present study	designed the study	Conceived and designed the experiments	Methodology	YES
6047954	30014313	ITH	2	designed the study|contributed to the data analysis and interpretation|supervised the whole part of the present study	contributed to the data analysis and interpretation	Analyzed the data	Formal analysis	YES
6047954	30014313	ITH	2	designed the study|contributed to the data analysis and interpretation|supervised the whole part of the present study	supervised the whole part of the present study	-	Supervision	YES
6047954	30014313	JLH	2	designed the study|contributed to the data analysis and interpretation|contributed to the drafting of the manuscript together with the corresponding authors	designed the study	Conceived and designed the experiments	Methodology	YES
6047954	30014313	JLH	2	designed the study|contributed to the data analysis and interpretation|contributed to the drafting of the manuscript together with the corresponding authors	contributed to the data analysis and interpretation	Analyzed the data	Formal analysis	YES
6047954	30014313	JLH	2	designed the study|contributed to the data analysis and interpretation|contributed to the drafting of the manuscript together with the corresponding authors	contributed to the drafting of the manuscript together with the corresponding authors	Wrote the paper	Writing - Original Draft	YES
6047954	30014313	KJL	2	designed the study|contributed to the data analysis and interpretation|contributed to the drafting of the manuscript together with the corresponding authors	designed the study	Conceived and designed the experiments	Methodology	YES
6047954	30014313	KJL	2	designed the study|contributed to the data analysis and interpretation|contributed to the drafting of the manuscript together with the corresponding authors	contributed to the data analysis and interpretation	Analyzed the data	Formal analysis	YES
6047954	30014313	KJL	2	designed the study|contributed to the data analysis and interpretation|contributed to the drafting of the manuscript together with the corresponding authors	contributed to the drafting of the manuscript together with the corresponding authors	Wrote the paper	Writing - Original Draft	YES
6047954	30014313	KLH	2	designed the study|contributed to the patient selection and data acquisition|contributed to the data analysis and interpretation|contributed to the drafting of the manuscript together with the corresponding authors	designed the study	Conceived and designed the experiments	Methodology	YES
6047954	30014313	KLH	2	designed the study|contributed to the patient selection and data acquisition|contributed to the data analysis and interpretation|contributed to the drafting of the manuscript together with the corresponding authors	contributed to the patient selection and data acquisition	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
6047954	30014313	KLH	2	designed the study|contributed to the patient selection and data acquisition|contributed to the data analysis and interpretation|contributed to the drafting of the manuscript together with the corresponding authors	contributed to the data analysis and interpretation	Analyzed the data	Formal analysis	YES
6047954	30014313	KLH	2	designed the study|contributed to the patient selection and data acquisition|contributed to the data analysis and interpretation|contributed to the drafting of the manuscript together with the corresponding authors	contributed to the drafting of the manuscript together with the corresponding authors	Wrote the paper	Writing - Original Draft	YES
6047954	30014313	MYH	2	contributed to the data analysis and interpretation|contributed to the drafting of the manuscript together with the corresponding authors	contributed to the data analysis and interpretation	Analyzed the data	Formal analysis	YES
6047954	30014313	MYH	2	contributed to the data analysis and interpretation|contributed to the drafting of the manuscript together with the corresponding authors	contributed to the drafting of the manuscript together with the corresponding authors	Wrote the paper	Writing - Original Draft	YES
6047954	30014313	NO	2	designed the study|contributed to the data analysis and interpretation|contributed to the critical revision of the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
6047954	30014313	NO	2	designed the study|contributed to the data analysis and interpretation|contributed to the critical revision of the manuscript	contributed to the data analysis and interpretation	Analyzed the data	Formal analysis	YES
6047954	30014313	NO	2	designed the study|contributed to the data analysis and interpretation|contributed to the critical revision of the manuscript	contributed to the critical revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
6047954	30014313	SPW	2	designed the study|contributed to the critical revision of the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
6047954	30014313	SPW	2	designed the study|contributed to the critical revision of the manuscript	contributed to the critical revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
6047954	30014313	TCY	2	designed the study|contributed to the critical revision of the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
6047954	30014313	TCY	2	designed the study|contributed to the critical revision of the manuscript	contributed to the critical revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
6047954	30014313	THL	2	designed the study|contributed to the patient selection and data acquisition|contributed to the data analysis and interpretation|supervised the whole part of the present study	designed the study	Conceived and designed the experiments	Methodology	YES
6047954	30014313	THL	2	designed the study|contributed to the patient selection and data acquisition|contributed to the data analysis and interpretation|supervised the whole part of the present study	contributed to the patient selection and data acquisition	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
6047954	30014313	THL	2	designed the study|contributed to the patient selection and data acquisition|contributed to the data analysis and interpretation|supervised the whole part of the present study	contributed to the data analysis and interpretation	Analyzed the data	Formal analysis	YES
6047954	30014313	THL	2	designed the study|contributed to the patient selection and data acquisition|contributed to the data analysis and interpretation|supervised the whole part of the present study	supervised the whole part of the present study	-	Supervision	YES
6047954	30014313	TYC	2	contributed to the patient selection and data acquisition|contributed to the critical revision of the manuscript	contributed to the patient selection and data acquisition	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
6047954	30014313	TYC	2	contributed to the patient selection and data acquisition|contributed to the critical revision of the manuscript	contributed to the critical revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
6047954	30014313	YJC	2	contributed to the patient selection and data acquisition|contributed to the critical revision of the manuscript	contributed to the patient selection and data acquisition	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
6047954	30014313	YJC	2	contributed to the patient selection and data acquisition|contributed to the critical revision of the manuscript	contributed to the critical revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
6047954	30014313	YMW	2	contributed to the patient selection and data acquisition|contributed to the data analysis and interpretation|contributed to the critical revision of the manuscript	contributed to the patient selection and data acquisition	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
6047954	30014313	YMW	2	contributed to the patient selection and data acquisition|contributed to the data analysis and interpretation|contributed to the critical revision of the manuscript	contributed to the data analysis and interpretation	Analyzed the data	Formal analysis	YES
6047954	30014313	YMW	2	contributed to the patient selection and data acquisition|contributed to the data analysis and interpretation|contributed to the critical revision of the manuscript	contributed to the critical revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
1892806	17593968	AC	PLoS5	Contributed to the analysis of the data and content of the paper	Contributed to the analysis of the data and content of the paper	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
1892806	17593968	BP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1892806	17593968	BP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1892806	17593968	DL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1892806	17593968	DL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1892806	17593968	DL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1892806	17593968	GS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1892806	17593968	GS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1892806	17593968	JD	PLoS5	Analyzed the data|Contributed to the content of the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1892806	17593968	JD	PLoS5	Analyzed the data|Contributed to the content of the paper	Contributed to the content of the paper	-	-	NO
1892806	17593968	SC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1892806	17593968	SC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1892806	17593968	SC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1892806	17593968	SD	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1892806	17593968	SD	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1892806	17593968	ST	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1892806	17593968	ST	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1892806	17593968	TZ	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1892806	17593968	TZ	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4943918	27411334	AS	1	Experimentation|Drafting	Experimentation	Performed the experiments	Investigation	YES
4943918	27411334	AS	1	Experimentation|Drafting	Drafting	Wrote the paper	Writing - Original Draft	YES
4943918	27411334	MK	1	Planning and designing of study|Experimentation|Analysis|Drafting	Planning and designing of study	Conceived and designed the experiments	Methodology	YES
4943918	27411334	MK	1	Planning and designing of study|Experimentation|Analysis|Drafting	Experimentation	Performed the experiments	Investigation	YES
4943918	27411334	MK	1	Planning and designing of study|Experimentation|Analysis|Drafting	Analysis	-	-	NO
4943918	27411334	MK	1	Planning and designing of study|Experimentation|Analysis|Drafting	Drafting	Wrote the paper	Writing - Original Draft	YES
4943918	27411334	RKS	1	Planning and designing of study|Analysis	Planning and designing of study	Conceived and designed the experiments	Methodology	YES
4943918	27411334	RKS	1	Planning and designing of study|Analysis	Analysis	-	-	NO
4943918	27411334	VB	1	Analysis	Analysis	-	-	NO
5725467	29270188	HS	2	performed the experiments and data analysis|wrote the manuscript	performed the experiments and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5725467	29270188	HS	2	performed the experiments and data analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5725467	29270188	JA	2	designed and supervised the study|wrote the manuscript	designed and supervised the study	Conceived and designed the experiments	Methodology|Supervision	YES
5725467	29270188	JA	2	designed and supervised the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5725467	29270188	PS	2	designed, performed, and analyzed data from the experiments|wrote the manuscript	designed, performed, and analyzed data from the experiments	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5725467	29270188	PS	2	designed, performed, and analyzed data from the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6054601	30030665	All authors	2	were involved in the editing process	were involved in the editing process	Wrote the paper	Writing - Review & Editing	YES
6054601	30030665	JMR	2	assisted in implementation of kinetic analysis tools	assisted in implementation of kinetic analysis tools	Performed the experiments	Investigation	YES
6054601	30030665	RCM	2	processed clinical studies and assisted in creation of figures	processed clinical studies and assisted in creation of figures	-	Visualization	YES
6054601	30030665	RSB	2	supervised project development and analysis	supervised project development and analysis	-	Supervision	YES
6054601	30030665	RdK	2	formulated partial volume correction|supervised project development and analysis	formulated partial volume correction	Conceived and designed the experiments	Conceptualization	YES
6054601	30030665	RdK	2	formulated partial volume correction|supervised project development and analysis	supervised project development and analysis	-	Supervision	YES
6054601	30030665	TW	2	performed kinetic analysis, created figures, and wrote the manuscript|formulated partial volume correction	performed kinetic analysis, created figures, and wrote the manuscript	Performed the experiments|Wrote the paper	Investigation|Visualization|Writing - Original Draft	YES
6054601	30030665	TW	2	performed kinetic analysis, created figures, and wrote the manuscript|formulated partial volume correction	formulated partial volume correction	Conceived and designed the experiments	Conceptualization	YES
1892807	17593975	AG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1892807	17593975	AM	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Wrote the paper|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1892807	17593975	AM	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Wrote the paper|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1892807	17593975	AM	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Wrote the paper|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1892807	17593975	AM	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Wrote the paper|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1892807	17593975	AM	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Wrote the paper|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1892807	17593975	AM	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Wrote the paper|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1892807	17593975	AM	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Wrote the paper|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1892807	17593975	AZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1892807	17593975	BS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1892807	17593975	CL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1892807	17593975	CZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1892807	17593975	CZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1892807	17593975	CZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1892807	17593975	EV	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1892807	17593975	EV	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1892807	17593975	GR	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1892807	17593975	GR	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1892807	17593975	JB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1892807	17593975	JB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1892807	17593975	JB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1892807	17593975	MS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1892807	17593975	MT	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1892807	17593975	MW	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1892807	17593975	VK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4414507	25923661	BB	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414507	25923661	BB	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4414507	25923661	DG	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414507	25923661	DG	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414507	25923661	DG	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414507	25923661	DG	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414507	25923661	LT	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4414507	25923661	MH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414507	25923661	MH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414507	25923661	MH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414507	25923661	MT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414507	25923661	MT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414507	25923661	MT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414507	25923661	MT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414507	25923661	MT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414507	25923661	PG	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414507	25923661	PG	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414507	25923661	PG	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414507	25923661	PG	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414507	25923661	SM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414507	25923661	SM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414507	25923661	SM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5596874	28899343	CSH	1	Conception and design|Principal investigator of the project	Conception and design	Conceived and designed the experiments	Conceptualization	YES
5596874	28899343	CSH	1	Conception and design|Principal investigator of the project	Principal investigator of the project	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
5596874	28899343	HYJ	1	Conception and design|Experimental part, analysis and interpretation of data|Preparation of the manuscript|Sample collection and maintaining patient database	Conception and design	Conceived and designed the experiments	Conceptualization	YES
5596874	28899343	HYJ	1	Conception and design|Experimental part, analysis and interpretation of data|Preparation of the manuscript|Sample collection and maintaining patient database	Experimental part, analysis and interpretation of data	Analyzed the data	Formal analysis	YES
5596874	28899343	HYJ	1	Conception and design|Experimental part, analysis and interpretation of data|Preparation of the manuscript|Sample collection and maintaining patient database	Preparation of the manuscript	Wrote the paper	Writing - Original Draft	YES
5596874	28899343	HYJ	1	Conception and design|Experimental part, analysis and interpretation of data|Preparation of the manuscript|Sample collection and maintaining patient database	Sample collection and maintaining patient database	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5596874	28899343	KDW	1	Preparation of the manuscript|Sample collection and maintaining patient database	Preparation of the manuscript	Wrote the paper	Writing - Original Draft	YES
5596874	28899343	KDW	1	Preparation of the manuscript|Sample collection and maintaining patient database	Sample collection and maintaining patient database	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5596874	28899343	KHJ	1	Experimental part, analysis and interpretation of data|Preparation of the manuscript	Experimental part, analysis and interpretation of data	Analyzed the data	Formal analysis	YES
5596874	28899343	KHJ	1	Experimental part, analysis and interpretation of data|Preparation of the manuscript	Preparation of the manuscript	Wrote the paper	Writing - Original Draft	YES
5596874	28899343	LJH	1	Conception and design|Experimental part, analysis and interpretation of data|Preparation of the manuscript	Conception and design	Conceived and designed the experiments	Conceptualization	YES
5596874	28899343	LJH	1	Conception and design|Experimental part, analysis and interpretation of data|Preparation of the manuscript	Experimental part, analysis and interpretation of data	Analyzed the data	Formal analysis	YES
5596874	28899343	LJH	1	Conception and design|Experimental part, analysis and interpretation of data|Preparation of the manuscript	Preparation of the manuscript	Wrote the paper	Writing - Original Draft	YES
5596874	28899343	PSY	1	Experimental part, analysis and interpretation of data	Experimental part, analysis and interpretation of data	Analyzed the data	Formal analysis	YES
5596874	28899343	RHM	1	Conception and design|Sample collection and maintaining patient database|Principal investigator of the project	Conception and design	Conceived and designed the experiments	Conceptualization	YES
5596874	28899343	RHM	1	Conception and design|Sample collection and maintaining patient database|Principal investigator of the project	Sample collection and maintaining patient database	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5596874	28899343	RHM	1	Conception and design|Sample collection and maintaining patient database|Principal investigator of the project	Principal investigator of the project	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
6054830	30032450	AV	2	were involved in the conception and design of the study|critically revised the manuscript for important intellectual content	were involved in the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6054830	30032450	AV	2	were involved in the conception and design of the study|critically revised the manuscript for important intellectual content	critically revised the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
6054830	30032450	CT	2	clinical data	clinical data	-	-	NO
6054830	30032450	GP	2	performed statistical analysis|critically revised the manuscript for important intellectual content	performed statistical analysis	Analyzed the data	Formal analysis	YES
6054830	30032450	GP	2	performed statistical analysis|critically revised the manuscript for important intellectual content	critically revised the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
6054830	30032450	MS	2	were involved in the conception and design of the study|have contributed equally to the manuscript and share the first authorship	were involved in the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6054830	30032450	MS	2	were involved in the conception and design of the study|have contributed equally to the manuscript and share the first authorship	have contributed equally to the manuscript and share the first authorship	-	-	NO
6054830	30032450	ST	2	were involved in the conception and design of the study|have contributed equally to the manuscript and share the first authorship	were involved in the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6054830	30032450	ST	2	were involved in the conception and design of the study|have contributed equally to the manuscript and share the first authorship	have contributed equally to the manuscript and share the first authorship	-	-	NO
6054830	30032450	VR	2	were involved in the conception and design of the study|critically revised the manuscript for important intellectual content	were involved in the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6054830	30032450	VR	2	were involved in the conception and design of the study|critically revised the manuscript for important intellectual content	critically revised the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5725473	29270190	GW	2	performed most of the experiments	performed most of the experiments	Performed the experiments	Investigation	YES
5725473	29270190	LW	2	performed most of the experiments	performed most of the experiments	Performed the experiments	Investigation	YES
5725473	29270190	XL	2	conceived the project and designed the experiments|wrote the manuscript	conceived the project and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5725473	29270190	XL	2	conceived the project and designed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5725473	29270190	YF	2	participated in the preparation of at2g21280 antibodies	participated in the preparation of at2g21280 antibodies	Performed the experiments	Investigation	YES
5725473	29270190	YL	2	performed most of the experiments|wrote the manuscript	performed most of the experiments	Performed the experiments	Investigation	YES
5725473	29270190	YL	2	performed most of the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
1892808	17579725	CC	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1892808	17579725	CC	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1892808	17579725	JY	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1892808	17579725	JY	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1892808	17579725	RW	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1892808	17579725	RW	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4958086	27447701	DMD-M	PLoS5	Conceived and designed the experiments|Analyzed the data and results|Wrote the manuscript|Directed and supervised this study|Prepared figures and tables	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4958086	27447701	DMD-M	PLoS5	Conceived and designed the experiments|Analyzed the data and results|Wrote the manuscript|Directed and supervised this study|Prepared figures and tables	Analyzed the data and results	Analyzed the data	Formal analysis	YES
4958086	27447701	DMD-M	PLoS5	Conceived and designed the experiments|Analyzed the data and results|Wrote the manuscript|Directed and supervised this study|Prepared figures and tables	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4958086	27447701	DMD-M	PLoS5	Conceived and designed the experiments|Analyzed the data and results|Wrote the manuscript|Directed and supervised this study|Prepared figures and tables	Directed and supervised this study	-	Supervision	YES
4958086	27447701	DMD-M	PLoS5	Conceived and designed the experiments|Analyzed the data and results|Wrote the manuscript|Directed and supervised this study|Prepared figures and tables	Prepared figures and tables	-	Visualization	YES
4958086	27447701	EH-L	PLoS5	Conceived and designed the experiments|Analyzed the data and results|Wrote the manuscript|Directed and supervised this study|Prepared figures and tables	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4958086	27447701	EH-L	PLoS5	Conceived and designed the experiments|Analyzed the data and results|Wrote the manuscript|Directed and supervised this study|Prepared figures and tables	Analyzed the data and results	Analyzed the data	Formal analysis	YES
4958086	27447701	EH-L	PLoS5	Conceived and designed the experiments|Analyzed the data and results|Wrote the manuscript|Directed and supervised this study|Prepared figures and tables	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4958086	27447701	EH-L	PLoS5	Conceived and designed the experiments|Analyzed the data and results|Wrote the manuscript|Directed and supervised this study|Prepared figures and tables	Directed and supervised this study	-	Supervision	YES
4958086	27447701	EH-L	PLoS5	Conceived and designed the experiments|Analyzed the data and results|Wrote the manuscript|Directed and supervised this study|Prepared figures and tables	Prepared figures and tables	-	Visualization	YES
4958086	27447701	GH-C	PLoS5	Performed the experiments|Analyzed the data and results|Wrote the manuscript|Prepared figures and tables	Performed the experiments	Performed the experiments	Investigation	YES
4958086	27447701	GH-C	PLoS5	Performed the experiments|Analyzed the data and results|Wrote the manuscript|Prepared figures and tables	Analyzed the data and results	Analyzed the data	Formal analysis	YES
4958086	27447701	GH-C	PLoS5	Performed the experiments|Analyzed the data and results|Wrote the manuscript|Prepared figures and tables	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4958086	27447701	GH-C	PLoS5	Performed the experiments|Analyzed the data and results|Wrote the manuscript|Prepared figures and tables	Prepared figures and tables	-	Visualization	YES
4958086	27447701	HBE-B	PLoS5	Analyzed the data and results|Wrote the manuscript|Directed and supervised this study	Analyzed the data and results	Analyzed the data	Formal analysis	YES
4958086	27447701	HBE-B	PLoS5	Analyzed the data and results|Wrote the manuscript|Directed and supervised this study	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4958086	27447701	HBE-B	PLoS5	Analyzed the data and results|Wrote the manuscript|Directed and supervised this study	Directed and supervised this study	-	Supervision	YES
4958086	27447701	JC	PLoS5	Conceived and designed the experiments|Analyzed the data and results|Wrote the manuscript|Directed and supervised this study|Prepared figures and tables	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4958086	27447701	JC	PLoS5	Conceived and designed the experiments|Analyzed the data and results|Wrote the manuscript|Directed and supervised this study|Prepared figures and tables	Analyzed the data and results	Analyzed the data	Formal analysis	YES
4958086	27447701	JC	PLoS5	Conceived and designed the experiments|Analyzed the data and results|Wrote the manuscript|Directed and supervised this study|Prepared figures and tables	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4958086	27447701	JC	PLoS5	Conceived and designed the experiments|Analyzed the data and results|Wrote the manuscript|Directed and supervised this study|Prepared figures and tables	Directed and supervised this study	-	Supervision	YES
4958086	27447701	JC	PLoS5	Conceived and designed the experiments|Analyzed the data and results|Wrote the manuscript|Directed and supervised this study|Prepared figures and tables	Prepared figures and tables	-	Visualization	YES
4958086	27447701	JOV-R	PLoS5	Performed the experiments|Analyzed the data and results|Wrote the manuscript|Prepared figures and tables	Performed the experiments	Performed the experiments	Investigation	YES
4958086	27447701	JOV-R	PLoS5	Performed the experiments|Analyzed the data and results|Wrote the manuscript|Prepared figures and tables	Analyzed the data and results	Analyzed the data	Formal analysis	YES
4958086	27447701	JOV-R	PLoS5	Performed the experiments|Analyzed the data and results|Wrote the manuscript|Prepared figures and tables	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4958086	27447701	JOV-R	PLoS5	Performed the experiments|Analyzed the data and results|Wrote the manuscript|Prepared figures and tables	Prepared figures and tables	-	Visualization	YES
4958086	27447701	YG-G	PLoS5	Analyzed the data and results|Wrote the manuscript	Analyzed the data and results	Analyzed the data	Formal analysis	YES
4958086	27447701	YG-G	PLoS5	Analyzed the data and results|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4414508	25923114	ASC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4414508	25923114	ASC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414508	25923114	CKM	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414508	25923114	CKM	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414508	25923114	DJM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414508	25923114	DJM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414508	25923114	DJM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414508	25923114	DJM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414508	25923114	JJAL	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414508	25923114	JJAL	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414508	25923114	JLD	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414508	25923114	MH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4414508	25923114	PO	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4414508	25923114	PV	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414508	25923114	TH	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4414508	25923114	TH	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414508	25923114	WRM	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414508	25923114	WRM	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414508	25923114	WT	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414508	25923114	WT	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5596942	28899360	DR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5596942	28899360	DR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5596942	28899360	DR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5596942	28899360	MB	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5596942	28899360	MB	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5596942	28899360	PC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
5596942	28899360	PC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5596942	28899360	PC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5596942	28899360	SB	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5596942	28899360	SB	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6054831	30032355	AC	2	participated in the planning and design of the studies and wrote the manuscript|made the operations and patient follow-ups	participated in the planning and design of the studies and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
6054831	30032355	AC	2	participated in the planning and design of the studies and wrote the manuscript|made the operations and patient follow-ups	made the operations and patient follow-ups	Performed the experiments	Investigation	YES
6054831	30032355	JS	2	participated in the planning and design of the studies and wrote the manuscript	participated in the planning and design of the studies and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
6054831	30032355	SL	2	participated in the planning and design of the studies and wrote the manuscript	participated in the planning and design of the studies and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4609373	26504810	Shan-Wen Liu	2	contribute equally to this paper	contribute equally to this paper	-	-	NO
4609373	26504810	Tsung-Hsien Chen	2	contribute equally to this paper	contribute equally to this paper	-	-	NO
5725808	29270182	CS	PLoS52	performed the experiments and analyzed the data|wrote the article	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5725808	29270182	CS	PLoS52	performed the experiments and analyzed the data|wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
5725808	29270182	JY	PLoS52	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5725808	29270182	SD	PLoS52	conceived and designed the experiments|wrote the article	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5725808	29270182	SD	PLoS52	conceived and designed the experiments|wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
5725808	29270182	all the authors	PLoS52	read and commented on the article	read and commented on the article	-	-	NO
6050536	30079200	H.C.	PLoS52	developed the theory	developed the theory	-	-	NO
6050536	30079200	H.Y.	PLoS52	performed the dna hairpin unzipping and rezipping experiments	performed the dna hairpin unzipping and rezipping experiments	Performed the experiments	Investigation	YES
6050536	30079200	J.Y.	PLoS52	developed the theory|wrote the paper|conceived and supervised the study	developed the theory	-	-	NO
6050536	30079200	J.Y.	PLoS52	developed the theory|wrote the paper|conceived and supervised the study	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6050536	30079200	J.Y.	PLoS52	developed the theory|wrote the paper|conceived and supervised the study	conceived and supervised the study	Conceived and designed the experiments	Conceptualization|Supervision	YES
6050536	30079200	M.Y.	PLoS52	performed the calculations and data fitting	performed the calculations and data fitting	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6050536	30079200	Q.T.	PLoS52	performed the titin i27 domain unfolding experiments	performed the titin i27 domain unfolding experiments	Performed the experiments	Investigation	YES
6050536	30079200	S.G.	PLoS52	developed the theory|performed the calculations and data fitting|wrote the paper	developed the theory	-	-	NO
6050536	30079200	S.G.	PLoS52	developed the theory|performed the calculations and data fitting|wrote the paper	performed the calculations and data fitting	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6050536	30079200	S.G.	PLoS52	developed the theory|performed the calculations and data fitting|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6050536	30079200	S.L.	PLoS52	performed the titin i27 domain unfolding experiments	performed the titin i27 domain unfolding experiments	Performed the experiments	Investigation	YES
4958091	27447702	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
4414509	25923917	AB	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414509	25923917	AB	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414509	25923917	DD	PLoS5	Wrote the paper|Enabled illumina sequencing and barcoding setup	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414509	25923917	DD	PLoS5	Wrote the paper|Enabled illumina sequencing and barcoding setup	Enabled illumina sequencing and barcoding setup	Performed the experiments	Investigation	YES
4414509	25923917	FVN	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper|Enabled illumina sequencing and barcoding setup	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414509	25923917	FVN	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper|Enabled illumina sequencing and barcoding setup	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414509	25923917	FVN	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper|Enabled illumina sequencing and barcoding setup	Enabled illumina sequencing and barcoding setup	Performed the experiments	Investigation	YES
4414509	25923917	FW	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414509	25923917	FW	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414509	25923917	GS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414509	25923917	GS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414509	25923917	IM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Sampling	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414509	25923917	IM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Sampling	Analyzed the data	Analyzed the data	Formal analysis	YES
4414509	25923917	IM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Sampling	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414509	25923917	IM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Sampling	Sampling	Performed the experiments	Investigation	YES
4414509	25923917	KM	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414509	25923917	KM	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414509	25923917	LP	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Sampling	Performed the experiments	Performed the experiments	Investigation	YES
4414509	25923917	LP	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Sampling	Analyzed the data	Analyzed the data	Formal analysis	YES
4414509	25923917	LP	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Sampling	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414509	25923917	LP	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Sampling	Sampling	Performed the experiments	Investigation	YES
4414509	25923917	PV	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1892809	17593974	AA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1892809	17593974	AA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1892809	17593974	AA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1892809	17593974	BB	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1892809	17593974	BG	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1892809	17593974	BG	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1892809	17593974	BG	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1892809	17593974	CH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1892809	17593974	CH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1892809	17593974	CH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1892809	17593974	CH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1892809	17593974	DF	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1892809	17593974	DG	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1892809	17593974	DG	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1892809	17593974	GF	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1892809	17593974	HB	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1892809	17593974	HB	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1892809	17593974	KW	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1892809	17593974	KW	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1892809	17593974	MT	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1892809	17593974	RC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1892809	17593974	SC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
6057864	30043115	AI	2	study design, data collection and analysis, manuscript preparation	study design, data collection and analysis, manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
6057864	30043115	LB	2	data collection, data collection and analysis, manuscript preparation	data collection, data collection and analysis, manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6057864	30043115	NH	2	data collection	data collection	Performed the experiments	Investigation	YES
6057864	30043115	PG	2	data analysis	data analysis	Analyzed the data	Formal analysis	YES
6057864	30043115	RH	2	study design and data analysis	study design and data analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
6057864	30043115	RW	2	study design	study design	Conceived and designed the experiments	Methodology	YES
6057864	30043115	SP	2	study design, data collection and analysis, manuscript preparation	study design, data collection and analysis, manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
6057864	30043115	SV	2	study design and data analysis	study design and data analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
6057864	30043115	TY	2	data analysis	data analysis	Analyzed the data	Formal analysis	YES
5596945	28899340	All authors	PLoS52	contributed to the conception and design of the study|contributed to writing and editing of the manuscript	contributed to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5596945	28899340	All authors	PLoS52	contributed to the conception and design of the study|contributed to writing and editing of the manuscript	contributed to writing and editing of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5596945	28899340	CML	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5596945	28899340	JNP	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5725826	29270187	GS	2	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5725826	29270187	RD	2	interpreted data, revised the manuscript critically	interpreted data, revised the manuscript critically	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5725826	29270187	SD	2	provided technical assistance to xs	provided technical assistance to xs	Performed the experiments	Investigation	YES
5725826	29270187	XS	2	performed the experiments and analyzed the data|drafted parts of the manuscript	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5725826	29270187	XS	2	performed the experiments and analyzed the data|drafted parts of the manuscript	drafted parts of the manuscript	Wrote the paper	Writing - Original Draft	YES
5725826	29270187	YP	2	conceived the project, supervised the experiments, and completed the writing	conceived the project, supervised the experiments, and completed the writing	Conceived and designed the experiments|Wrote the paper	Conceptualization|Supervision	YES
4960098	27457245	AS	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
4960098	27457245	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4960098	27457245	IAD	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
4960098	27457245	MMarvasi	2	conceived experiments|wrote the manuscript|performed the statistical analysis	conceived experiments	Conceived and designed the experiments	Conceptualization	YES
4960098	27457245	MMarvasi	2	conceived experiments|wrote the manuscript|performed the statistical analysis	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4960098	27457245	MMarvasi	2	conceived experiments|wrote the manuscript|performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
4960098	27457245	MMatuszewska	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
4960098	27457245	RCP	2	performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
4960098	27457245	THA	2	wrote the manuscript|performed the statistical analysis	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4960098	27457245	THA	2	wrote the manuscript|performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
4414510	25923667	KM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414510	25923667	KM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414510	25923667	KM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414510	25923667	PB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414510	25923667	PB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414510	25923667	PB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414510	25923667	PB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414510	25923667	PB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414510	25923667	SAW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414510	25923667	SAW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414510	25923667	SAW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414510	25923667	SAW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414510	25923667	SAW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414510	25923667	ZU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414510	25923667	ZU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414510	25923667	ZU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414510	25923667	ZU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414510	25923667	ZU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6060188	30046944	CGH	2	performed the tissue biopsies	performed the tissue biopsies	Performed the experiments	Investigation	YES
6060188	30046944	DJB	2	performed histopathological analysis	performed histopathological analysis	Performed the experiments	Investigation	YES
6060188	30046944	DMS	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
6060188	30046944	EEP	2	performed the data analysis and wrote the manuscript	performed the data analysis and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6060188	30046944	II	2	helped with the data analysis and image construction	helped with the data analysis and image construction	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
6060188	30046944	JJO	2	performed the tissue biopsies	performed the tissue biopsies	Performed the experiments	Investigation	YES
6060188	30046944	JN	2	helped with the data analysis and image construction	helped with the data analysis and image construction	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
6060188	30046944	MB	2	performed the data analysis and wrote the manuscript	performed the data analysis and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6060188	30046944	MMG	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
6060188	30046944	VA	2	helped with the data analysis and image construction	helped with the data analysis and image construction	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
1894649	17593976	AR	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1894649	17593976	AR	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1894649	17593976	AR	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1894649	17593976	AR	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1894649	17593976	DJ	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1894649	17593976	DJ	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1894649	17593976	DM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1894649	17593976	DM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1894649	17593976	DZ	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1894649	17593976	ET	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1894649	17593976	FK	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1894649	17593976	FK	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1894649	17593976	JL	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1894649	17593976	JR	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1894649	17593976	JR	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1894649	17593976	LB	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1894649	17593976	MF	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1894649	17593976	SM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1894649	17593976	SM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1894649	17593976	SM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1894649	17593976	TM	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1894649	17593976	TM	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1894649	17593976	YH	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1894649	17593976	YH	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1894649	17593976	ZS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1894649	17593976	ZS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414511	25923140	CR	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414511	25923140	DC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414511	25923140	DC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414511	25923140	DC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414511	25923140	DS	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414511	25923140	KVB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414511	25923140	KVB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414511	25923140	KVB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414511	25923140	LS	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414511	25923140	LW	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414511	25923140	MYA	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414511	25923140	MYA	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414511	25923140	ND	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414511	25923140	ND	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5727051	29276520	CA	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5727051	29276520	FL	PLoS52	designed the research|performed the experiments|analyzed the data	designed the research	Conceived and designed the experiments	Methodology	YES
5727051	29276520	FL	PLoS52	designed the research|performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5727051	29276520	FL	PLoS52	designed the research|performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5727051	29276520	GB	PLoS52	designed the research|analyzed the data|coordinated and helped to draft the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
5727051	29276520	GB	PLoS52	designed the research|analyzed the data|coordinated and helped to draft the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5727051	29276520	GB	PLoS52	designed the research|analyzed the data|coordinated and helped to draft the manuscript	coordinated and helped to draft the manuscript	Wrote the paper	Project administration|Writing - Original Draft	YES
5727051	29276520	JM	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5727051	29276520	MB	PLoS52	provided in vitro translated proteins	provided in vitro translated proteins	Performed the experiments	Investigation	YES
5727051	29276520	MF	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5727051	29276520	NH	PLoS52	designed the research|performed the experiments|analyzed the data	designed the research	Conceived and designed the experiments	Methodology	YES
5727051	29276520	NH	PLoS52	designed the research|performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5727051	29276520	NH	PLoS52	designed the research|performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5727051	29276520	PM	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5727051	29276520	SS	PLoS52	provided in vitro translated proteins	provided in vitro translated proteins	Performed the experiments	Investigation	YES
5727051	29276520	SV	PLoS52	provided in vitro translated proteins	provided in vitro translated proteins	Performed the experiments	Investigation	YES
5727051	29276520	UC	PLoS52	designed the research|coordinated and helped to draft the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
5727051	29276520	UC	PLoS52	designed the research|coordinated and helped to draft the manuscript	coordinated and helped to draft the manuscript	Wrote the paper	Project administration|Writing - Original Draft	YES
5727051	29276520	WH	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5727051	29276520	WH	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
4414512	25923709	CG	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4414512	25923709	ED	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414512	25923709	FB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414512	25923709	FB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414512	25923709	FB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414512	25923709	FB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414512	25923709	FB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414512	25923709	LF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414512	25923709	LF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414512	25923709	LF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414512	25923709	LF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414512	25923709	MCG	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4414512	25923709	MCG	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4414512	25923709	VC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1894650	17593978	CI	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1894650	17593978	CI	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1894650	17593978	CI	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1894650	17593978	CJ	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1894650	17593978	GA	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1894650	17593978	PB	PLoS5	Made the initial proposal to develop this software, contributed useful ideas regarding its implementation, provided constructive criticisms on the manuscript	Made the initial proposal to develop this software, contributed useful ideas regarding its implementation, provided constructive criticisms on the manuscript	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Investigation|Software|Writing - Original Draft	YES
6063804	30054846	AAL	PLoS52	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
6063804	30054846	ADW	PLoS52	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
6063804	30054846	All authors	PLoS52	contributed to the interpretation of the results and writing the manuscript	contributed to the interpretation of the results and writing the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6063804	30054846	BNMB	PLoS52	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
6063804	30054846	JvdA	PLoS52	designed the study|performed the experiments and acquired the data|analyzed the data	designed the study	Conceived and designed the experiments	Methodology	YES
6063804	30054846	JvdA	PLoS52	designed the study|performed the experiments and acquired the data|analyzed the data	performed the experiments and acquired the data	Performed the experiments	Investigation	YES
6063804	30054846	JvdA	PLoS52	designed the study|performed the experiments and acquired the data|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
6063804	30054846	LAS	PLoS52	performed the experiments and acquired the data	performed the experiments and acquired the data	Performed the experiments	Investigation	YES
6063804	30054846	MvdP	PLoS52	performed the experiments and acquired the data|analyzed the data	performed the experiments and acquired the data	Performed the experiments	Investigation	YES
6063804	30054846	MvdP	PLoS52	performed the experiments and acquired the data|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
6063804	30054846	RB	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
6063804	30054846	RCS	PLoS52	performed the experiments and acquired the data	performed the experiments and acquired the data	Performed the experiments	Investigation	YES
6063804	30054846	SSVG	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5598006	28903739	AC	2	supervised the research	supervised the research	-	Supervision	YES
5598006	28903739	BM	2	organised the epidemiologic part of the work	organised the epidemiologic part of the work	-	-	NO
5598006	28903739	DGH	2	performed the experiments and analysed the data	performed the experiments and analysed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5598006	28903739	DP	2	organised the epidemiologic part of the work	organised the epidemiologic part of the work	-	-	NO
5598006	28903739	FS	2	organised the epidemiologic part of the work	organised the epidemiologic part of the work	-	-	NO
5598006	28903739	IAB	2	organised the epidemiologic part of the work	organised the epidemiologic part of the work	-	-	NO
5598006	28903739	IL	2	performed the experiments and analysed the data	performed the experiments and analysed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5598006	28903739	IV	2	performed the experiments and analysed the data	performed the experiments and analysed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5598006	28903739	JCSK	2	designed the research|supervised the research	designed the research	Conceived and designed the experiments	Methodology	YES
5598006	28903739	JCSK	2	designed the research|supervised the research	supervised the research	-	Supervision	YES
5598006	28903739	JK	2	performed the experiments and analysed the data	performed the experiments and analysed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5598006	28903739	JV	2	supervised the research	supervised the research	-	Supervision	YES
5598006	28903739	MC-H	2	supervised the research	supervised the research	-	Supervision	YES
5598006	28903739	PG	2	designed the research|performed the experiments and analysed the data|wrote and all authors commented on the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
5598006	28903739	PG	2	designed the research|performed the experiments and analysed the data|wrote and all authors commented on the manuscript	performed the experiments and analysed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5598006	28903739	PG	2	designed the research|performed the experiments and analysed the data|wrote and all authors commented on the manuscript	wrote and all authors commented on the manuscript	Wrote the paper	Writing - Original Draft	YES
5598006	28903739	PV	2	designed the research|supervised the research	designed the research	Conceived and designed the experiments	Methodology	YES
5598006	28903739	PV	2	designed the research|supervised the research	supervised the research	-	Supervision	YES
5598006	28903739	RCHV	2	supervised the research	supervised the research	-	Supervision	YES
5598006	28903739	SAK	2	designed the research|supervised the research|wrote and all authors commented on the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
5598006	28903739	SAK	2	designed the research|supervised the research|wrote and all authors commented on the manuscript	supervised the research	-	Supervision	YES
5598006	28903739	SAK	2	designed the research|supervised the research|wrote and all authors commented on the manuscript	wrote and all authors commented on the manuscript	Wrote the paper	Writing - Original Draft	YES
5598006	28903739	TMCMK	2	supervised the research	supervised the research	-	Supervision	YES
5598006	28903739	The EnviroGenomarkers	2	consortium contributed to the design and conduct of the research and the evaluation of the results	consortium contributed to the design and conduct of the research and the evaluation of the results	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5727067	29276522	IM	2	planned and performed the experiments|analyzed and discussed the results obtained	planned and performed the experiments	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5727067	29276522	IM	2	planned and performed the experiments|analyzed and discussed the results obtained	analyzed and discussed the results obtained	Analyzed the data	Formal analysis	YES
5727067	29276522	PM	2	analyzed and discussed the results obtained	analyzed and discussed the results obtained	Analyzed the data	Formal analysis	YES
4970986	27485518	ARISA	2	sequencing, as part of his doctoral thesis	sequencing, as part of his doctoral thesis	Performed the experiments	Investigation	YES
4970986	27485518	AW	2	contributed arisa analysis, statistical data evaluation, and sequencing data	contributed arisa analysis, statistical data evaluation, and sequencing data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
4970986	27485518	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4970986	27485518	W. All	2	three authors were involved in data interpretation and the writing of the paper	three authors were involved in data interpretation and the writing of the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4609379	26504831	A. M. Mes-Masson	2	conceived the study, participated in its design and coordination, and helped to draft the paper	conceived the study, participated in its design and coordination, and helped to draft the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
4609379	26504831	D. Provencher	2	conceived the study, participated in its design and coordination, and helped to draft the paper	conceived the study, participated in its design and coordination, and helped to draft the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
4609379	26504831	G. Chene	2	conceived the study, participated in its design and coordination, and helped to draft the paper|validated all antibodies using western blot	conceived the study, participated in its design and coordination, and helped to draft the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
4609379	26504831	G. Chene	2	conceived the study, participated in its design and coordination, and helped to draft the paper|validated all antibodies using western blot	validated all antibodies using western blot	Performed the experiments	Investigation|Validation	YES
4609379	26504831	TMA	2	validated all antibodies using western blot	validated all antibodies using western blot	Performed the experiments	Investigation|Validation	YES
1894651	17593971	DG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1894651	17593971	DG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1894651	17593971	EL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1894651	17593971	KL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1894651	17593971	MP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1894651	17593971	PD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1894651	17593971	PD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1894651	17593971	PD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1894651	17593971	PD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1894651	17593971	PD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1894651	17593971	VA	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1894651	17593971	VA	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1894651	17593971	WZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4414513	25923775	AGA	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414513	25923775	AGA	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414513	25923775	AGA	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414513	25923775	BI	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414513	25923775	BI	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414513	25923775	BI	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414513	25923775	JA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414513	25923775	JA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414513	25923775	JA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414513	25923775	JA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414513	25923775	JA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414513	25923775	JAL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414513	25923775	JAL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414513	25923775	JAL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414513	25923775	KI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414513	25923775	KI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414513	25923775	KI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414513	25923775	KI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414513	25923775	KI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414513	25923775	KMF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414513	25923775	KMF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414513	25923775	KMF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414513	25923775	LH	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4414513	25923775	LH	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414513	25923775	NH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414513	25923775	NH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414513	25923775	NH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414513	25923775	NH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414513	25923775	RJH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414513	25923775	RJH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414513	25923775	RJH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414513	25923775	VF	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414513	25923775	VF	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6063806	30054750	DP	2	performed the delineation of lesions, helped with data and result interpretation, and commented on the manuscript	performed the delineation of lesions, helped with data and result interpretation, and commented on the manuscript	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6063806	30054750	EtV	2	performed the study design, performed the retrospective reconstructions, obtained the data, performed the statistical analysis, and wrote the manuscript	performed the study design, performed the retrospective reconstructions, obtained the data, performed the statistical analysis, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
6063806	30054750	GD	2	provided technical support for the applied pettoolbox, commented on study design, helped with data and result interpretation, and commented on the manuscript	provided technical support for the applied pettoolbox, commented on study design, helped with data and result interpretation, and commented on the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Methodology|Resources	YES
6063806	30054750	HN	2	performed the delineation of lesions, helped with data and result interpretation, and commented on the manuscript	performed the delineation of lesions, helped with data and result interpretation, and commented on the manuscript	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6063806	30054750	IB	2	was the principle investigator, commented on the study design, did patient inclusion, helped with data and result interpretation, and commented on the manuscript	was the principle investigator, commented on the study design, did patient inclusion, helped with data and result interpretation, and commented on the manuscript	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
6063806	30054750	JM	2	performed the delineation of lesions, helped with data and result interpretation, and commented on the manuscript	performed the delineation of lesions, helped with data and result interpretation, and commented on the manuscript	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6063806	30054750	UM	2	performed the delineation of lesions, helped with data and result interpretation, and commented on the manuscript	performed the delineation of lesions, helped with data and result interpretation, and commented on the manuscript	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5598043	28903734	FY	PLoS52	helped in collecting data and data analysis	helped in collecting data and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5598043	28903734	HD	PLoS52	helped in collecting data and data analysis	helped in collecting data and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5598043	28903734	JS	PLoS52	conceptualized the idea and revised the manuscript	conceptualized the idea and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5598043	28903734	NS	PLoS52	helped in collecting data and data analysis	helped in collecting data and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5598043	28903734	YX	PLoS52	wrote this manuscript|performed the experiments	wrote this manuscript	Wrote the paper	Writing - Original Draft	YES
5598043	28903734	YX	PLoS52	wrote this manuscript|performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5598043	28903734	YZ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
4970993	27485517	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4970993	27485517	BK	2	performed research	performed research	Performed the experiments	Investigation	YES
4970993	27485517	JWP	2	designed research and wrote the paper|analyzed data	designed research and wrote the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4970993	27485517	JWP	2	designed research and wrote the paper|analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
4970993	27485517	NHH	2	designed research and wrote the paper|performed research|analyzed data	designed research and wrote the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4970993	27485517	NHH	2	designed research and wrote the paper|performed research|analyzed data	performed research	Performed the experiments	Investigation	YES
4970993	27485517	NHH	2	designed research and wrote the paper|performed research|analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
4970993	27485517	NLH	2	performed research|analyzed data	performed research	Performed the experiments	Investigation	YES
4970993	27485517	NLH	2	performed research|analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
4970993	27485517	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5727076	29276527	CH	2	provided suggestions and revised the manuscript	provided suggestions and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5727076	29276527	GL	2	performed the experiments, analyzed the data, wrote and revised the manuscript	performed the experiments, analyzed the data, wrote and revised the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5727076	29276527	HS	2	conceived and directed this study, analyzed the data, wrote and revised the manuscript	conceived and directed this study, analyzed the data, wrote and revised the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
5727076	29276527	SF	2	performed the experiments, analyzed the data, wrote and revised the manuscript	performed the experiments, analyzed the data, wrote and revised the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5727076	29276527	WH	2	performed the experiments, analyzed the data, wrote and revised the manuscript	performed the experiments, analyzed the data, wrote and revised the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5727076	29276527	XL	2	performed the experiments, analyzed the data, wrote and revised the manuscript	performed the experiments, analyzed the data, wrote and revised the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5727076	29276527	YW	2	performed the experiments, analyzed the data, wrote and revised the manuscript	performed the experiments, analyzed the data, wrote and revised the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
4414514	25923119	FF	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414514	25923119	FF	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414514	25923119	JZ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414514	25923119	LG	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414514	25923119	LG	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414514	25923119	YL	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4414514	25923119	YL	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4414514	25923119	YX	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4414514	25923119	YX	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4414514	25923119	ZW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414514	25923119	ZW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414514	25923119	ZW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414514	25923119	ZW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414514	25923119	ZW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6066589	30062395	AVV	2	drafted the manuscript|performed the statistical analysis|acquired the data	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
6066589	30062395	AVV	2	drafted the manuscript|performed the statistical analysis|acquired the data	performed the statistical analysis	Analyzed the data	Formal analysis	YES
6066589	30062395	AVV	2	drafted the manuscript|performed the statistical analysis|acquired the data	acquired the data	Performed the experiments	Investigation	YES
6066589	30062395	All authors	2	conceived the study and participated in the design and coordination|contributed to data design, analysis, and interpretation|contributed to writing or critiquing drafts of the manuscript and approval of the final manuscript before publication	conceived the study and participated in the design and coordination	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
6066589	30062395	All authors	2	conceived the study and participated in the design and coordination|contributed to data design, analysis, and interpretation|contributed to writing or critiquing drafts of the manuscript and approval of the final manuscript before publication	contributed to data design, analysis, and interpretation	Conceived and designed the experiments|Analyzed the data	Formal analysis	YES
6066589	30062395	All authors	2	conceived the study and participated in the design and coordination|contributed to data design, analysis, and interpretation|contributed to writing or critiquing drafts of the manuscript and approval of the final manuscript before publication	contributed to writing or critiquing drafts of the manuscript and approval of the final manuscript before publication	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6066589	30062395	JFM	2	performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
6066589	30062395	JP	2	coordinated the radiochemistry production	coordinated the radiochemistry production	-	Project administration	YES
6066589	30062395	NK	2	performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
6066589	30062395	ST	2	acquired the data	acquired the data	Performed the experiments	Investigation	YES
4609380	26504838	All authors	2	participated in research design, writing of the paper, and data analysis, and all authors read and approved the final paper	participated in research design, writing of the paper, and data analysis, and all authors read and approved the final paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5602860	28915794	BW	PLoS52	conceived and planned the research|performed bioinformatics analysis and microscopic observation|wrote the paper	conceived and planned the research	Conceived and designed the experiments	Conceptualization	YES
5602860	28915794	BW	PLoS52	conceived and planned the research|performed bioinformatics analysis and microscopic observation|wrote the paper	performed bioinformatics analysis and microscopic observation	Performed the experiments	Formal analysis|Investigation	YES
5602860	28915794	BW	PLoS52	conceived and planned the research|performed bioinformatics analysis and microscopic observation|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5602860	28915794	GS	PLoS52	initiated and coordinated the project|conceived and planned the research|revised the manuscript	initiated and coordinated the project	Conceived and designed the experiments	Conceptualization|Project administration	YES
5602860	28915794	GS	PLoS52	initiated and coordinated the project|conceived and planned the research|revised the manuscript	conceived and planned the research	Conceived and designed the experiments	Conceptualization	YES
5602860	28915794	GS	PLoS52	initiated and coordinated the project|conceived and planned the research|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5602860	28915794	MLG	PLoS52	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5602860	28915794	RZ	PLoS52	conceived and planned the research	conceived and planned the research	Conceived and designed the experiments	Conceptualization	YES
5602860	28915794	XL	PLoS52	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4970999	27485516	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4970999	27485516	KK	2	participated in the design of the research	participated in the design of the research	Conceived and designed the experiments	Methodology	YES
4970999	27485516	MG	2	helped with the experiments	helped with the experiments	Performed the experiments	Investigation	YES
4970999	27485516	WYZ	2	carried out the experiment, analyzed the batch fermentation and transcriptome data, and drafted the manuscript	carried out the experiment, analyzed the batch fermentation and transcriptome data, and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4970999	27485516	YQT	2	designed the research, helped with the data analysis, and revised the manuscript	designed the research, helped with the data analysis, and revised the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
4970999	27485516	ZYX	2	helped with the experiments	helped with the experiments	Performed the experiments	Investigation	YES
4414515	25923692	C-CL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414515	25923692	DH	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414515	25923692	DH	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414515	25923692	DH	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414515	25923692	G-GZ	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414515	25923692	G-GZ	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414515	25923692	H-CG	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4414515	25923692	L-FL	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414515	25923692	L-FL	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414515	25923692	XW	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4414515	25923692	Y-PB	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414515	25923692	Y-PB	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414515	25923692	YL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5727088	29276526	All authors	2	interpreted the data and reviewed the manuscript	interpreted the data and reviewed the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5727088	29276526	CM	2	designed the field experiments and provided support with the 3d numerical modeling	designed the field experiments and provided support with the 3d numerical modeling	Conceived and designed the experiments|Performed the experiments	Formal analysis|Investigation|Methodology	YES
5727088	29276526	CO	2	proposed the diurnal field experiments and modeling scenarios	proposed the diurnal field experiments and modeling scenarios	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
5727088	29276526	MA	2	provided support with the modeling	provided support with the modeling	Performed the experiments	Methodology	YES
5727088	29276526	MH	2	provided support with the modeling	provided support with the modeling	Performed the experiments	Methodology	YES
5727088	29276526	MV	2	performed the field experiments, analyzed the data, performed the modeling and wrote the manuscript	performed the field experiments, analyzed the data, performed the modeling and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
1894652	17611619	AM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1894652	17611619	AP	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1894652	17611619	DA	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1894652	17611619	DA	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1894652	17611619	DA	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1894652	17611619	GB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1894652	17611619	GB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1894652	17611619	HB	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1894652	17611619	JM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1894652	17611619	JM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1894652	17611619	JM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1894652	17611619	KW	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1894652	17611619	SB	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1894652	17611619	UB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1894652	17611619	UB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1894652	17611619	UB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4047772	24910543	AW	2	interpreted the data	interpreted the data	Analyzed the data	Formal analysis	YES
4047772	24910543	All authors	2	were involved in drafting the manuscript and have given final approval of the published version	were involved in drafting the manuscript and have given final approval of the published version	Wrote the paper	Writing - Original Draft	YES
4047772	24910543	CAR	2	interpreted the data	interpreted the data	Analyzed the data	Formal analysis	YES
4047772	24910543	FIK	2	interpreted the data	interpreted the data	Analyzed the data	Formal analysis	YES
4047772	24910543	JF	2	interpreted the data	interpreted the data	Analyzed the data	Formal analysis	YES
4047772	24910543	JH	2	interpreted the data	interpreted the data	Analyzed the data	Formal analysis	YES
4414516	25923230	BX	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414516	25923230	BX	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414516	25923230	BX	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414516	25923230	BX	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414516	25923230	LC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4414516	25923230	ND	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414516	25923230	ND	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414516	25923230	ND	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414516	25923230	ND	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414516	25923230	ND	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414516	25923230	XT	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414516	25923230	XT	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414516	25923230	XT	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6068050	30066053	AAL	2	had contributed to the conception and design of the study	had contributed to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6068050	30066053	ADW	2	have contributed to acquisition of the data	have contributed to acquisition of the data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
6068050	30066053	All authors	2	have critically revised the manuscript and approved its final content	have critically revised the manuscript and approved its final content	Wrote the paper	Writing - Review & Editing	YES
6068050	30066053	MY	2	has contributed to acquisition, analysis and interpretation of the data	has contributed to acquisition, analysis and interpretation of the data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
6068050	30066053	NV	2	have contributed to acquisition and analysis of the data	have contributed to acquisition and analysis of the data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
6068050	30066053	OSH	2	has contributed to the acquisition of the data and the design of the study	has contributed to the acquisition of the data and the design of the study	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources	YES
6068050	30066053	PCWH	2	has contributed to acquisition of the data and the conception and design of the study	has contributed to acquisition of the data and the conception and design of the study	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceptualization|Investigation|Methodology|Resources	YES
6068050	30066053	PJWP	2	have contributed to acquisition of the data	have contributed to acquisition of the data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
6068050	30066053	PW	2	have contributed to acquisition of the data	have contributed to acquisition of the data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
6068050	30066053	RB	2	has contributed to interpretation of the data and the design of the study	has contributed to interpretation of the data and the design of the study	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Methodology|Resources	YES
6068050	30066053	RCS	2	have contributed to acquisition and analysis of the data	have contributed to acquisition and analysis of the data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
6068050	30066053	TK	2	drafted the manuscript and contributed to analysis and interpretation of the data	drafted the manuscript and contributed to analysis and interpretation of the data	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
4609381	26504842	All	2	researchers were independent from funders	researchers were independent from funders	-	-	NO
4609381	26504842	Angela M. Craigie	2	carried out the analysis|drafted the paper which was revised by all authors	carried out the analysis	Performed the experiments	Investigation	YES
4609381	26504842	Angela M. Craigie	2	carried out the analysis|drafted the paper which was revised by all authors	drafted the paper which was revised by all authors	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4609381	26504842	Annie S. Anderson	2	drafted the paper which was revised by all authors	drafted the paper which was revised by all authors	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4609381	26504842	J. C. Steele	2	designed the trial parameters and formed the investigator group who obtained the funding|were responsible for overseeing study implementation and data collection	designed the trial parameters and formed the investigator group who obtained the funding	Conceived and designed the experiments	Funding acquisition|Methodology	YES
4609381	26504842	J. C. Steele	2	designed the trial parameters and formed the investigator group who obtained the funding|were responsible for overseeing study implementation and data collection	were responsible for overseeing study implementation and data collection	Performed the experiments	Investigation|Supervision	YES
4609381	26504842	Martine Stead	2	carried out the analysis|drafted the paper which was revised by all authors	carried out the analysis	Performed the experiments	Investigation	YES
4609381	26504842	Martine Stead	2	carried out the analysis|drafted the paper which was revised by all authors	drafted the paper which was revised by all authors	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4609381	26504842	Maureen Macleod	2	carried out the analysis|drafted the paper which was revised by all authors	carried out the analysis	Performed the experiments	Investigation	YES
4609381	26504842	Maureen Macleod	2	carried out the analysis|drafted the paper which was revised by all authors	drafted the paper which was revised by all authors	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4609381	26504842	Stephen Caswell	2	were responsible for overseeing study implementation and data collection|carried out the analysis	were responsible for overseeing study implementation and data collection	Performed the experiments	Investigation|Supervision	YES
4609381	26504842	Stephen Caswell	2	were responsible for overseeing study implementation and data collection|carried out the analysis	carried out the analysis	Performed the experiments	Investigation	YES
5602955	28915789	AE	PLoS52	performed the gc-ms analyses	performed the gc-ms analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5602955	28915789	DKH	PLoS52	designed the experiments|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5602955	28915789	DKH	PLoS52	designed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5602955	28915789	EZ	PLoS52	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5602955	28915789	JA	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5602955	28915789	JK	PLoS52	performed the gc-ms analyses	performed the gc-ms analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5602955	28915789	MP	PLoS52	designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5602955	28915789	MP	PLoS52	designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5602955	28915789	MP	PLoS52	designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5602955	28915789	MP	PLoS52	designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5602955	28915789	all authors	PLoS52	read the manuscript, edited and commented on it before submission	read the manuscript, edited and commented on it before submission	Wrote the paper	Writing - Review & Editing	YES
4414518	25923765	CPL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414518	25923765	CPL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414518	25923765	CPL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414518	25923765	CPL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414518	25923765	MEM	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414518	25923765	MEM	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414518	25923765	RCD	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414518	25923765	RCD	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4974214	27491862	AR	2	have conceived and designed experiments|have contributed reagents/analysis tools|have written the research paper	have conceived and designed experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4974214	27491862	AR	2	have conceived and designed experiments|have contributed reagents/analysis tools|have written the research paper	have contributed reagents/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4974214	27491862	AR	2	have conceived and designed experiments|have contributed reagents/analysis tools|have written the research paper	have written the research paper	Wrote the paper	Writing - Original Draft	YES
4974214	27491862	ARS	2	have contributed reagents/analysis tools	have contributed reagents/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4974214	27491862	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4974214	27491862	MAN	2	have performed the experiments|have analyzed the data	have performed the experiments	Performed the experiments	Investigation	YES
4974214	27491862	MAN	2	have performed the experiments|have analyzed the data	have analyzed the data	Analyzed the data	Formal analysis	YES
4974214	27491862	SZ	2	have performed the experiments	have performed the experiments	Performed the experiments	Investigation	YES
4974214	27491862	SZH	2	have performed the experiments|have analyzed the data	have performed the experiments	Performed the experiments	Investigation	YES
4974214	27491862	SZH	2	have performed the experiments|have analyzed the data	have analyzed the data	Analyzed the data	Formal analysis	YES
4974214	27491862	ZK	2	have conceived and designed experiments|have performed the experiments|have analyzed the data|have written the research paper	have conceived and designed experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4974214	27491862	ZK	2	have conceived and designed experiments|have performed the experiments|have analyzed the data|have written the research paper	have performed the experiments	Performed the experiments	Investigation	YES
4974214	27491862	ZK	2	have conceived and designed experiments|have performed the experiments|have analyzed the data|have written the research paper	have analyzed the data	Analyzed the data	Formal analysis	YES
4974214	27491862	ZK	2	have conceived and designed experiments|have performed the experiments|have analyzed the data|have written the research paper	have written the research paper	Wrote the paper	Writing - Original Draft	YES
4048621	24910544	All authors	2	contributed equally to this manuscript	contributed equally to this manuscript	-	-	NO
1894653	17593963	AG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1894653	17593963	AG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1894653	17593963	AG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1894653	17593963	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1894653	17593963	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1894653	17593963	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1894653	17593963	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1894653	17593963	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1894653	17593963	MT	PLoS5	Lead	Lead	-	-	NO
1894653	17593963	Overall Project	PLoS5	Other	Other	-	-	NO
5727089	29276525	Both authors	2	analyzed and interpreted the data	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5727089	29276525	S. Both	2	authors read and approved the final version of the manuscript	authors read and approved the final version of the manuscript	-	-	NO
6070450	30069789	BW	2	performed the experiments and analysed the data	performed the experiments and analysed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6070450	30069789	ECC	2	analysed the data and wrote the manuscript	analysed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6070450	30069789	GN	2	performed the experiments, analysed the data, and wrote the manuscript	performed the experiments, analysed the data, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6070450	30069789	HM	2	conceived and designed the study and wrote the manuscript	conceived and designed the study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
6070450	30069789	JCR	2	conceived and designed the study and wrote the manuscript	conceived and designed the study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
6070450	30069789	KA	2	performed the experiments, analysed the data, and wrote the manuscript	performed the experiments, analysed the data, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6070450	30069789	MF	2	performed the experiments, analysed the data, and wrote the manuscript	performed the experiments, analysed the data, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6070450	30069789	MLT	2	performed the experiments and analysed the data	performed the experiments and analysed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6070450	30069789	SNR	2	analysed the data and wrote the manuscript	analysed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6070450	30069789	SU	2	performed the experiments, analysed the data, and wrote the manuscript	performed the experiments, analysed the data, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4049453	24914402	ABT	2	designed the study and acquired the data	designed the study and acquired the data	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4049453	24914402	AP	2	interpreted and analysed the data	interpreted and analysed the data	Analyzed the data	Formal analysis	YES
4049453	24914402	All of the authors	2	approve the final version of the manuscript	approve the final version of the manuscript	-	-	NO
4049453	24914402	DXS	2	designed the study and acquired the data	designed the study and acquired the data	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4049453	24914402	GSF	2	designed the study and acquired the data	designed the study and acquired the data	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4049453	24914402	LFB	2	interpreted and analysed the data|revised intellectual and critically the manuscript	interpreted and analysed the data	Analyzed the data	Formal analysis	YES
4049453	24914402	LFB	2	interpreted and analysed the data|revised intellectual and critically the manuscript	revised intellectual and critically the manuscript	Wrote the paper	Writing - Review & Editing	YES
4049453	24914402	PCFM	2	revised intellectual and critically the manuscript	revised intellectual and critically the manuscript	Wrote the paper	Writing - Review & Editing	YES
4049453	24914402	RMG	2	designed the study and acquired the data	designed the study and acquired the data	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4049453	24914402	SG	2	interpreted and analysed the data	interpreted and analysed the data	Analyzed the data	Formal analysis	YES
4049453	24914402	TAR	2	interpreted and analysed the data|revised intellectual and critically the manuscript	interpreted and analysed the data	Analyzed the data	Formal analysis	YES
4049453	24914402	TAR	2	interpreted and analysed the data|revised intellectual and critically the manuscript	revised intellectual and critically the manuscript	Wrote the paper	Writing - Review & Editing	YES
4049453	24914402	WR	2	designed the study and acquired the data	designed the study and acquired the data	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4993724	27549808	AZ	PLoS52	conceived the idea and designed the experiments|carried out the experiments|analyzed the data|wrote the manuscript	conceived the idea and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4993724	27549808	AZ	PLoS52	conceived the idea and designed the experiments|carried out the experiments|analyzed the data|wrote the manuscript	carried out the experiments	Performed the experiments	Investigation	YES
4993724	27549808	AZ	PLoS52	conceived the idea and designed the experiments|carried out the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
4993724	27549808	AZ	PLoS52	conceived the idea and designed the experiments|carried out the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4993724	27549808	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4993724	27549808	CC	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
4993724	27549808	XH	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
4993724	27549808	XW	PLoS52	conceived the idea and designed the experiments|analyzed the data|wrote the manuscript	conceived the idea and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4993724	27549808	XW	PLoS52	conceived the idea and designed the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
4993724	27549808	XW	PLoS52	conceived the idea and designed the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4993724	27549808	YL	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5603072	28915793	CL	2	edited the manuscript|coordinated the study	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5603072	28915793	CL	2	edited the manuscript|coordinated the study	coordinated the study	-	Project administration	YES
5603072	28915793	ER	2	contributed to the analysis	contributed to the analysis	-	-	NO
5603072	28915793	GD	2	contributed to the analysis|edited the manuscript	contributed to the analysis	-	-	NO
5603072	28915793	GD	2	contributed to the analysis|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5603072	28915793	GM	2	conceived and designed the study|contributed to the analysis|edited the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5603072	28915793	GM	2	conceived and designed the study|contributed to the analysis|edited the manuscript	contributed to the analysis	-	-	NO
5603072	28915793	GM	2	conceived and designed the study|contributed to the analysis|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5603072	28915793	JMA	2	produced the sequencing data|edited the manuscript	produced the sequencing data	Performed the experiments	Investigation	YES
5603072	28915793	JMA	2	produced the sequencing data|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5603072	28915793	KL	2	produced the sequencing data|edited the manuscript	produced the sequencing data	Performed the experiments	Investigation	YES
5603072	28915793	KL	2	produced the sequencing data|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5603072	28915793	OF	2	performed dna extractions and molecular experiments	performed dna extractions and molecular experiments	Performed the experiments	Investigation	YES
5603072	28915793	XA	2	conceived and designed the study|performed the analysis and wrote the manuscript|edited the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5603072	28915793	XA	2	conceived and designed the study|performed the analysis and wrote the manuscript|edited the manuscript	performed the analysis and wrote the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5603072	28915793	XA	2	conceived and designed the study|performed the analysis and wrote the manuscript|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
1894654	17593973	CH	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1894654	17593973	CH	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1894654	17593973	HO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1894654	17593973	HO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1894654	17593973	HO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1894654	17593973	HO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1894654	17593973	NK	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1894654	17593973	NK	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5727091	29276524	B-CK	PLoS5	Conceived and designed the experiments|Revised the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5727091	29276524	B-CK	PLoS5	Conceived and designed the experiments|Revised the manuscript	Revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5727091	29276524	DC	PLoS5	Revised the manuscript	Revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5727091	29276524	GC	PLoS5	Participated in phenotyping	Participated in phenotyping	Performed the experiments	Investigation	YES
5727091	29276524	HL	PLoS5	Revised the manuscript	Revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5727091	29276524	JJ	PLoS5	Conceived and designed the experiments|Participated in phenotyping|Participated in marker development and genetic mapping|Drafted the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5727091	29276524	JJ	PLoS5	Conceived and designed the experiments|Participated in phenotyping|Participated in marker development and genetic mapping|Drafted the manuscript	Participated in phenotyping	Performed the experiments	Investigation	YES
5727091	29276524	JJ	PLoS5	Conceived and designed the experiments|Participated in phenotyping|Participated in marker development and genetic mapping|Drafted the manuscript	Participated in marker development and genetic mapping	Performed the experiments	Investigation	YES
5727091	29276524	JJ	PLoS5	Conceived and designed the experiments|Participated in phenotyping|Participated in marker development and genetic mapping|Drafted the manuscript	Drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5727091	29276524	JV	PLoS5	Drafted the manuscript|Revised the manuscript	Drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5727091	29276524	JV	PLoS5	Drafted the manuscript|Revised the manuscript	Revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4061773	24944546	CR	2	conceived of the study and carried out data acquisition, analysis, interpretation, and was the principal writer for the manuscript	conceived of the study and carried out data acquisition, analysis, interpretation, and was the principal writer for the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
4061773	24944546	EP	2	participated in data acquisition and was a manuscript reviewer	participated in data acquisition and was a manuscript reviewer	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4061773	24944546	GW	2	conceived of the study and was a manuscript reviewer/reviser	conceived of the study and was a manuscript reviewer/reviser	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
4061773	24944546	MG	2	was the medical advisor and was a manuscript reviewer/reviser	was the medical advisor and was a manuscript reviewer/reviser	Wrote the paper	Writing - Review & Editing	YES
4061773	24944546	MP	2	carried out data interpretation and was a manuscript reviewer/reviser	carried out data interpretation and was a manuscript reviewer/reviser	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4061773	24944546	PK	2	was the research supervisor for the study and was involved in its conception|also assisted in the statistical analysis and interpretation of the results, and was the senior manuscript writer/reviser	was the research supervisor for the study and was involved in its conception	Conceived and designed the experiments	Conceptualization|Supervision	YES
4061773	24944546	PK	2	was the research supervisor for the study and was involved in its conception|also assisted in the statistical analysis and interpretation of the results, and was the senior manuscript writer/reviser	also assisted in the statistical analysis and interpretation of the results, and was the senior manuscript writer/reviser	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
4061773	24944546	YM	2	participated in data acquisition and was a manuscript reviewer	participated in data acquisition and was a manuscript reviewer	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
6070454	30069645	All authors	2	designed the study|critically revised the article and approved of the final version for publication	designed the study	Conceived and designed the experiments	Methodology	YES
6070454	30069645	All authors	2	designed the study|critically revised the article and approved of the final version for publication	critically revised the article and approved of the final version for publication	Wrote the paper	Writing - Review & Editing	YES
6070454	30069645	CH	2	conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
6070454	30069645	GJM	2	analyzed the data and interpreted the results	analyzed the data and interpreted the results	Analyzed the data	Formal analysis	YES
6070454	30069645	LF	2	conceived the study|analyzed the data and interpreted the results|drafted the article	conceived the study	Conceived and designed the experiments	Conceptualization	YES
6070454	30069645	LF	2	conceived the study|analyzed the data and interpreted the results|drafted the article	analyzed the data and interpreted the results	Analyzed the data	Formal analysis	YES
6070454	30069645	LF	2	conceived the study|analyzed the data and interpreted the results|drafted the article	drafted the article	Wrote the paper	Writing - Original Draft	YES
6070454	30069645	PS	2	conceived the study|did the screening and examination of the subjects|analyzed the data and interpreted the results|drafted the article	conceived the study	Conceived and designed the experiments	Conceptualization	YES
6070454	30069645	PS	2	conceived the study|did the screening and examination of the subjects|analyzed the data and interpreted the results|drafted the article	did the screening and examination of the subjects	Performed the experiments	Investigation	YES
6070454	30069645	PS	2	conceived the study|did the screening and examination of the subjects|analyzed the data and interpreted the results|drafted the article	analyzed the data and interpreted the results	Analyzed the data	Formal analysis	YES
6070454	30069645	PS	2	conceived the study|did the screening and examination of the subjects|analyzed the data and interpreted the results|drafted the article	drafted the article	Wrote the paper	Writing - Original Draft	YES
4609383	26504836	C. O. Rodrigues	2	conducted conception and design of the study, acquisition of the data, analysis and interpretation of the data, and drafting of the paper	conducted conception and design of the study, acquisition of the data, analysis and interpretation of the data, and drafting of the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4609383	26504836	Eliane Ignotti	2	did conception and design, interpretation of the data, and critical revision of the paper	did conception and design, interpretation of the data, and critical revision of the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Review & Editing	YES
4609383	26504836	Emerson S. Santos	2	did analysis and interpretation of the data	did analysis and interpretation of the data	Analyzed the data	Formal analysis	YES
4609383	26504836	Sandra S. Hacon	2	did interpretation of the data and critical revision of the paper	did interpretation of the data and critical revision of the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
1895887	17611622	AW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1895887	17611622	AW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1895887	17611622	CT	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1895887	17611622	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1895887	17611622	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1895887	17611622	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1895887	17611622	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1895887	17611622	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1895887	17611622	MW	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4414520	25923712	AAA	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4414520	25923712	AAA	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4414520	25923712	AAA	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414520	25923712	SHM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414520	25923712	SHM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414520	25923712	SHM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414520	25923712	SHM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414520	25923712	SHM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4071077	24966805	AW	2	interpreted the data	interpreted the data	Analyzed the data	Formal analysis	YES
4071077	24966805	All authors	2	were involved in drafting the manuscript and have given final approval of the published version	were involved in drafting the manuscript and have given final approval of the published version	Wrote the paper	Writing - Original Draft	YES
4071077	24966805	CAR	2	interpreted the data	interpreted the data	Analyzed the data	Formal analysis	YES
4071077	24966805	FIK	2	interpreted the data	interpreted the data	Analyzed the data	Formal analysis	YES
4071077	24966805	JH	2	interpreted the data	interpreted the data	Analyzed the data	Formal analysis	YES
4996802	27558018	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4996802	27558018	BY	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
4996802	27558018	CCH	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
4996802	27558018	JDH	PLoS52	designed the experiment|wrote the manuscript	designed the experiment	Conceived and designed the experiments	Methodology	YES
4996802	27558018	JDH	PLoS52	designed the experiment|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4996802	27558018	LS	PLoS52	designed the experiment|performed the experiments|wrote the manuscript	designed the experiment	Conceived and designed the experiments	Methodology	YES
4996802	27558018	LS	PLoS52	designed the experiment|performed the experiments|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
4996802	27558018	LS	PLoS52	designed the experiment|performed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6070455	30069753	All authors	2	contributed to data processing and manuscript revision	contributed to data processing and manuscript revision	Analyzed the data|Wrote the paper	Data curation|Writing - Review & Editing	YES
6070455	30069753	DM	2	drafted the manuscript and performed data analysis|contributed to data acquisition	drafted the manuscript and performed data analysis	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6070455	30069753	DM	2	drafted the manuscript and performed data analysis|contributed to data acquisition	contributed to data acquisition	Performed the experiments	Investigation	YES
6070455	30069753	GH	2	contributed to data acquisition	contributed to data acquisition	Performed the experiments	Investigation	YES
6070455	30069753	MS	2	contributed to data acquisition	contributed to data acquisition	Performed the experiments	Investigation	YES
6070455	30069753	RM	2	contributed to data acquisition	contributed to data acquisition	Performed the experiments	Investigation	YES
5727094	29276521	AN	7	established experimental design	established experimental design	Conceived and designed the experiments	Methodology	YES
5727094	29276521	CS	7	performed statistical analysis of the field trials	performed statistical analysis of the field trials	Analyzed the data	Formal analysis	YES
5727094	29276521	KB	7	designed crop modeling evaluation	designed crop modeling evaluation	Conceived and designed the experiments|Performed the experiments	Methodology	YES
5727094	29276521	LG	7	provided guidance for crop trial evaluation	provided guidance for crop trial evaluation	-	Supervision	YES
5727094	29276521	LP	7	established experimental design	established experimental design	Conceived and designed the experiments	Methodology	YES
5727094	29276521	LS	7	provided guidance for crop trial evaluation, and interpreted data for the work	provided guidance for crop trial evaluation, and interpreted data for the work	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources|Supervision	YES
5727094	29276521	RS	7	planned the field trial, performed the statistical analysis of the field trials, and drafted the work	planned the field trial, performed the statistical analysis of the field trials, and drafted the work	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
5604118	28923023	All authors	2	edited and approved the final manuscript	edited and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5604118	28923023	CDG	2	designed and performed the experiments|supervised the project	designed and performed the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5604118	28923023	CDG	2	designed and performed the experiments|supervised the project	supervised the project	-	Supervision	YES
5604118	28923023	GIM	2	supervised the project	supervised the project	-	Supervision	YES
5604118	28923023	LMY	2	designed the study|designed and performed the experiments|analysed the data and wrote the initial draft of the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5604118	28923023	LMY	2	designed the study|designed and performed the experiments|analysed the data and wrote the initial draft of the manuscript	designed and performed the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5604118	28923023	LMY	2	designed the study|designed and performed the experiments|analysed the data and wrote the initial draft of the manuscript	analysed the data and wrote the initial draft of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5604118	28923023	SAR	2	designed the study|supervised the project	designed the study	Conceived and designed the experiments	Methodology	YES
5604118	28923023	SAR	2	designed the study|supervised the project	supervised the project	-	Supervision	YES
5604118	28923023	VM	2	designed and performed the experiments	designed and performed the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4609384	26504837	Jozsef Kaszaki	2	contributed equally to this work	contributed equally to this work	-	-	NO
4609384	26504837	Peter Palagyi	2	contributed equally to this work	contributed equally to this work	-	-	NO
1895888	17611617	CJ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1895888	17611617	MS	PLoS5	Lemeer	Lemeer	-	-	NO
1895888	17611617	RR	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1895888	17611617	RR	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1895888	17611617	SL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4073191	24976800	All authors	2	have effectively contributed to this work in its different production stages	have effectively contributed to this work in its different production stages	-	-	NO
4414521	25923711	AS	PLoS5	Analyzed the data|Edited the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4414521	25923711	AS	PLoS5	Analyzed the data|Edited the manuscript	Edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
4414521	25923711	BH	PLoS5	Analyzed the data|Edited the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4414521	25923711	BH	PLoS5	Analyzed the data|Edited the manuscript	Edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
4414521	25923711	CCS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4414521	25923711	CCS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4414521	25923711	CKK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Edited the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414521	25923711	CKK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Edited the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4414521	25923711	CKK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Edited the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4414521	25923711	CKK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Edited the manuscript	Edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
4414521	25923711	DMS	PLoS5	Analyzed the data|Edited the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4414521	25923711	DMS	PLoS5	Analyzed the data|Edited the manuscript	Edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
4414521	25923711	HAA	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4414521	25923711	HAA	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4414521	25923711	HJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Edited the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414521	25923711	HJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Edited the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4414521	25923711	HJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Edited the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4414521	25923711	HJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Edited the manuscript	Edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
4414521	25923711	NM	PLoS5	Conceived and designed the experiments|Analyzed the data|Edited the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414521	25923711	NM	PLoS5	Conceived and designed the experiments|Analyzed the data|Edited the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4414521	25923711	NM	PLoS5	Conceived and designed the experiments|Analyzed the data|Edited the manuscript	Edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
4414521	25923711	NPC-A	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Edited the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414521	25923711	NPC-A	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Edited the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4414521	25923711	NPC-A	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Edited the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4414521	25923711	NPC-A	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Edited the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414521	25923711	NPC-A	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Edited the manuscript	Edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
4414521	25923711	RS	PLoS5	Analyzed the data|Edited the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4414521	25923711	RS	PLoS5	Analyzed the data|Edited the manuscript	Edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
4414521	25923711	SdH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Edited the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414521	25923711	SdH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Edited the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4414521	25923711	SdH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Edited the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414521	25923711	SdH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Edited the manuscript	Edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
4414521	25923711	VB	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4414521	25923711	VB	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5604137	28923016	EH	2	provided analytical support and performed analysis|drafted the manuscript	provided analytical support and performed analysis	Performed the experiments	Investigation	YES
5604137	28923016	EH	2	provided analytical support and performed analysis|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5604137	28923016	HS	2	performed the laboratory work, data analysis and bioinformatics|drafted the manuscript	performed the laboratory work, data analysis and bioinformatics	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5604137	28923016	HS	2	performed the laboratory work, data analysis and bioinformatics|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5604137	28923016	JM	2	conceived and supervised the study|obtained funding|drafted the manuscript	conceived and supervised the study	Conceived and designed the experiments	Conceptualization|Supervision	YES
5604137	28923016	JM	2	conceived and supervised the study|obtained funding|drafted the manuscript	obtained funding	-	Funding acquisition	YES
5604137	28923016	JM	2	conceived and supervised the study|obtained funding|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5604137	28923016	LS	2	provided analytical support and developed the website database resource	provided analytical support and developed the website database resource	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources|Software	YES
5604137	28923016	NB	2	conceived and supervised the study	conceived and supervised the study	Conceived and designed the experiments	Conceptualization|Supervision	YES
4996803	27558019	HL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4996803	27558019	LT	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4996803	27558019	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4996803	27558019	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4996803	27558019	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4996803	27558019	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4996803	27558019	XZ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4996803	27558019	XZ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4996803	27558019	XZ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4996803	27558019	YP	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5728089	29276523	AL	PLoS52	designed the experiment|analyzed the data|wrote and organized the manuscript	designed the experiment	Conceived and designed the experiments	Methodology	YES
5728089	29276523	AL	PLoS52	designed the experiment|analyzed the data|wrote and organized the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5728089	29276523	AL	PLoS52	designed the experiment|analyzed the data|wrote and organized the manuscript	wrote and organized the manuscript	Wrote the paper	Writing - Original Draft	YES
5728089	29276523	All authors	PLoS52	contributed to the writing and revising of the manuscript	contributed to the writing and revising of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5728089	29276523	KG	PLoS52	designed the experiment	designed the experiment	Conceived and designed the experiments	Methodology	YES
5728089	29276523	S-EP	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5728089	29276523	TT	PLoS52	conducted the experiment and collected data	conducted the experiment and collected data	Performed the experiments	Investigation	YES
5728089	29276523	XS	PLoS52	conducted the experiment and collected data	conducted the experiment and collected data	Performed the experiments	Investigation	YES
5728089	29276523	XW	PLoS52	conducted the experiment and collected data	conducted the experiment and collected data	Performed the experiments	Investigation	YES
5728089	29276523	YG	PLoS52	conducted the experiment and collected data	conducted the experiment and collected data	Performed the experiments	Investigation	YES
5728089	29276523	YH	PLoS52	conducted the experiment and collected data	conducted the experiment and collected data	Performed the experiments	Investigation	YES
5728089	29276523	YL	PLoS52	conducted the experiment and collected data|designed the experiment|analyzed the data	conducted the experiment and collected data	Performed the experiments	Investigation	YES
5728089	29276523	YL	PLoS52	conducted the experiment and collected data|designed the experiment|analyzed the data	designed the experiment	Conceived and designed the experiments	Methodology	YES
5728089	29276523	YL	PLoS52	conducted the experiment and collected data|designed the experiment|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
6081875	30076556	AB	2	supervised the collection of all clinical data for dosimetry and the related quality control	supervised the collection of all clinical data for dosimetry and the related quality control	Performed the experiments	Data curation|Investigation|Supervision|Validation	YES
6081875	30076556	AD	2	contributed to the concept and design of the study|carried out all data analysis	contributed to the concept and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6081875	30076556	AD	2	contributed to the concept and design of the study|carried out all data analysis	carried out all data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6081875	30076556	AG	2	contributed to the concept and design of the study|carried out all data analysis	contributed to the concept and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6081875	30076556	AG	2	contributed to the concept and design of the study|carried out all data analysis	carried out all data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6081875	30076556	AT	2	contributed to the concept and design of the study|carried out all data analysis	contributed to the concept and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6081875	30076556	AT	2	contributed to the concept and design of the study|carried out all data analysis	carried out all data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6081875	30076556	All authors	2	contributed to the drafting of the manuscript, and all authors read and approved the manuscript	contributed to the drafting of the manuscript, and all authors read and approved the manuscript	Wrote the paper	Writing - Original Draft	YES
6081875	30076556	FJG	2	was responsible for radiopharmaceutical production	was responsible for radiopharmaceutical production	-	-	NO
6081875	30076556	GB	2	contributed to the concept and design of the study|carried out all data analysis	contributed to the concept and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6081875	30076556	GB	2	contributed to the concept and design of the study|carried out all data analysis	carried out all data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6081875	30076556	HI	2	contributed to the concept and design of the study|carried out all data analysis	contributed to the concept and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6081875	30076556	HI	2	contributed to the concept and design of the study|carried out all data analysis	carried out all data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6081875	30076556	JB	2	contributed to the concept and design of the study	contributed to the concept and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6081875	30076556	LV	2	contributed to the concept and design of the study	contributed to the concept and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6081875	30076556	PB	2	contributed to the concept and design of the study	contributed to the concept and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6081875	30076556	ST	2	contributed to the concept and design of the study|carried out all data analysis	contributed to the concept and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6081875	30076556	ST	2	contributed to the concept and design of the study|carried out all data analysis	carried out all data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6081875	30076556	SZ	2	contributed to the concept and design of the study	contributed to the concept and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4074833	24982601	AP	2	collected study data and followed patients	collected study data and followed patients	Performed the experiments	Investigation	YES
4074833	24982601	All Authors	2	have read and approved the final manuscript	have read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4074833	24982601	FD	2	collected study data and followed patients	collected study data and followed patients	Performed the experiments	Investigation	YES
4074833	24982601	FF	2	contributed to data interpretation and drafted the manuscript	contributed to data interpretation and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4074833	24982601	GA	2	contributed to data interpretation and drafted the manuscript	contributed to data interpretation and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4074833	24982601	JR	2	collected study data and followed patients	collected study data and followed patients	Performed the experiments	Investigation	YES
4074833	24982601	JT	2	collected study data and followed patients	collected study data and followed patients	Performed the experiments	Investigation	YES
4074833	24982601	ST	2	contributed to data interpretation and drafted the manuscript	contributed to data interpretation and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4074833	24982601	XV	2	collected study data and followed patients	collected study data and followed patients	Performed the experiments	Investigation	YES
1895889	17611626	AD	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1895889	17611626	AD	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1895889	17611626	BR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1895889	17611626	BR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1895889	17611626	BR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1895889	17611626	BR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1895889	17611626	BR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1895889	17611626	DK	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1895889	17611626	DK	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1895889	17611626	RA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1895889	17611626	RA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1895889	17611626	RA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414522	25923911	CS	PLoS5	Reviewed the literature	Reviewed the literature	-	Formal analysis	YES
4414522	25923911	DHP	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4414522	25923911	DHP	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4414522	25923911	HZL	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414522	25923911	JFU	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4414522	25923911	JFW	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414522	25923911	JFW	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414522	25923911	JHM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4414522	25923911	JHM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414522	25923911	LZ	PLoS5	Contributed reagents/materials/analysis tools|Proofread the article	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414522	25923911	LZ	PLoS5	Contributed reagents/materials/analysis tools|Proofread the article	Proofread the article	-	-	NO
4077550	24991195	AAC	2	were significant manuscript revisers/reviewers|participated in the concept and design|participated in data analysis and interpretation	were significant manuscript revisers/reviewers	Wrote the paper	Writing - Review & Editing	YES
4077550	24991195	AAC	2	were significant manuscript revisers/reviewers|participated in the concept and design|participated in data analysis and interpretation	participated in the concept and design	Conceived and designed the experiments	Conceptualization	YES
4077550	24991195	AAC	2	were significant manuscript revisers/reviewers|participated in the concept and design|participated in data analysis and interpretation	participated in data analysis and interpretation	Analyzed the data	Formal analysis	YES
4077550	24991195	AS	2	were significant manuscript revisers/reviewers|were responsible for data acquisition	were significant manuscript revisers/reviewers	Wrote the paper	Writing - Review & Editing	YES
4077550	24991195	AS	2	were significant manuscript revisers/reviewers|were responsible for data acquisition	were responsible for data acquisition	Performed the experiments	Investigation	YES
4077550	24991195	BF	2	were significant manuscript revisers/reviewers|were responsible for data acquisition	were significant manuscript revisers/reviewers	Wrote the paper	Writing - Review & Editing	YES
4077550	24991195	BF	2	were significant manuscript revisers/reviewers|were responsible for data acquisition	were responsible for data acquisition	Performed the experiments	Investigation	YES
4077550	24991195	CJG	2	were significant manuscript writers|participated in the concept and design|were responsible for data acquisition|participated in data analysis and interpretation	were significant manuscript writers	Wrote the paper	Writing - Original Draft	YES
4077550	24991195	CJG	2	were significant manuscript writers|participated in the concept and design|were responsible for data acquisition|participated in data analysis and interpretation	participated in the concept and design	Conceived and designed the experiments	Conceptualization	YES
4077550	24991195	CJG	2	were significant manuscript writers|participated in the concept and design|were responsible for data acquisition|participated in data analysis and interpretation	were responsible for data acquisition	Performed the experiments	Investigation	YES
4077550	24991195	CJG	2	were significant manuscript writers|participated in the concept and design|were responsible for data acquisition|participated in data analysis and interpretation	participated in data analysis and interpretation	Analyzed the data	Formal analysis	YES
4077550	24991195	GB	2	were significant manuscript writers|participated in the concept and design|participated in data analysis and interpretation	were significant manuscript writers	Wrote the paper	Writing - Original Draft	YES
4077550	24991195	GB	2	were significant manuscript writers|participated in the concept and design|participated in data analysis and interpretation	participated in the concept and design	Conceived and designed the experiments	Conceptualization	YES
4077550	24991195	GB	2	were significant manuscript writers|participated in the concept and design|participated in data analysis and interpretation	participated in data analysis and interpretation	Analyzed the data	Formal analysis	YES
4077550	24991195	MB	2	were significant manuscript revisers/reviewers|were responsible for data acquisition	were significant manuscript revisers/reviewers	Wrote the paper	Writing - Review & Editing	YES
4077550	24991195	MB	2	were significant manuscript revisers/reviewers|were responsible for data acquisition	were responsible for data acquisition	Performed the experiments	Investigation	YES
4077550	24991195	RH	2	were significant manuscript writers|participated in the concept and design|participated in data analysis and interpretation	were significant manuscript writers	Wrote the paper	Writing - Original Draft	YES
4077550	24991195	RH	2	were significant manuscript writers|participated in the concept and design|participated in data analysis and interpretation	participated in the concept and design	Conceived and designed the experiments	Conceptualization	YES
4077550	24991195	RH	2	were significant manuscript writers|participated in the concept and design|participated in data analysis and interpretation	participated in data analysis and interpretation	Analyzed the data	Formal analysis	YES
4077550	24991195	SJC	2	were significant manuscript revisers/reviewers|participated in the concept and design|participated in data analysis and interpretation	were significant manuscript revisers/reviewers	Wrote the paper	Writing - Review & Editing	YES
4077550	24991195	SJC	2	were significant manuscript revisers/reviewers|participated in the concept and design|participated in data analysis and interpretation	participated in the concept and design	Conceived and designed the experiments	Conceptualization	YES
4077550	24991195	SJC	2	were significant manuscript revisers/reviewers|participated in the concept and design|participated in data analysis and interpretation	participated in data analysis and interpretation	Analyzed the data	Formal analysis	YES
4077550	24991195	ZV	2	were significant manuscript revisers/reviewers|were responsible for data acquisition	were significant manuscript revisers/reviewers	Wrote the paper	Writing - Review & Editing	YES
4077550	24991195	ZV	2	were significant manuscript revisers/reviewers|were responsible for data acquisition	were responsible for data acquisition	Performed the experiments	Investigation	YES
5001958	27566647	AT	2	performed experiments and drafted the manuscript	performed experiments and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5001958	27566647	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5001958	27566647	JO	2	assisted with the data analysis	assisted with the data analysis	Analyzed the data	Formal analysis	YES
5001958	27566647	JS	2	managed the overall project and revised the manuscript	managed the overall project and revised the manuscript	Wrote the paper	Project administration|Writing - Review & Editing	YES
5001958	27566647	MO	2	isolated and identified the tested yeast strains and revised the manuscript	isolated and identified the tested yeast strains and revised the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5001958	27566647	MT	2	isolated and identified the tested yeast strains and revised the manuscript	isolated and identified the tested yeast strains and revised the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5001958	27566647	RE	2	isolated and identified the tested yeast strains and revised the manuscript	isolated and identified the tested yeast strains and revised the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5001958	27566647	SK	2	assisted with the data analysis	assisted with the data analysis	Analyzed the data	Formal analysis	YES
5001958	27566647	TS	2	isolated and identified the tested yeast strains and revised the manuscript	isolated and identified the tested yeast strains and revised the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
3836457	24307874	Dan Lu	2	contributed equally to this work	contributed equally to this work	-	-	NO
3836457	24307874	Junfeng Jiang	2	contributed equally to this work	contributed equally to this work	-	-	NO
6082247	30083998	All authors	2	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
6082247	30083998	HS	2	designed the study and developed the methodology|analyzed and interpreted the data and wrote the manuscript	designed the study and developed the methodology	Conceived and designed the experiments|Performed the experiments	Methodology	YES
6082247	30083998	HS	2	designed the study and developed the methodology|analyzed and interpreted the data and wrote the manuscript	analyzed and interpreted the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6082247	30083998	ML	2	designed the study and developed the methodology|performed the irradiation and processing of the blood samples and the calculations of the absorbed doses|analyzed and interpreted the data and wrote the manuscript	designed the study and developed the methodology	Conceived and designed the experiments|Performed the experiments	Methodology	YES
6082247	30083998	ML	2	designed the study and developed the methodology|performed the irradiation and processing of the blood samples and the calculations of the absorbed doses|analyzed and interpreted the data and wrote the manuscript	performed the irradiation and processing of the blood samples and the calculations of the absorbed doses	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
6082247	30083998	ML	2	designed the study and developed the methodology|performed the irradiation and processing of the blood samples and the calculations of the absorbed doses|analyzed and interpreted the data and wrote the manuscript	analyzed and interpreted the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6082247	30083998	SSc	2	designed the study and developed the methodology|analyzed and interpreted the data and wrote the manuscript	designed the study and developed the methodology	Conceived and designed the experiments|Performed the experiments	Methodology	YES
6082247	30083998	SSc	2	designed the study and developed the methodology|analyzed and interpreted the data and wrote the manuscript	analyzed and interpreted the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6082247	30083998	UE	2	designed the study and developed the methodology|analyzed and interpreted the data and wrote the manuscript	designed the study and developed the methodology	Conceived and designed the experiments|Performed the experiments	Methodology	YES
6082247	30083998	UE	2	designed the study and developed the methodology|analyzed and interpreted the data and wrote the manuscript	analyzed and interpreted the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4083353	25002835	AS	PLoS52	designed the experiments|performed the statistical analyses|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
4083353	25002835	AS	PLoS52	designed the experiments|performed the statistical analyses|wrote the manuscript	performed the statistical analyses	Analyzed the data	Formal analysis	YES
4083353	25002835	AS	PLoS52	designed the experiments|performed the statistical analyses|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4083353	25002835	DV	PLoS52	designed the experiments|performed the experiments|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
4083353	25002835	DV	PLoS52	designed the experiments|performed the experiments|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
4083353	25002835	DV	PLoS52	designed the experiments|performed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4083353	25002835	LS	PLoS52	designed the experiments|performed the experiments|performed the statistical analyses|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
4083353	25002835	LS	PLoS52	designed the experiments|performed the experiments|performed the statistical analyses|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
4083353	25002835	LS	PLoS52	designed the experiments|performed the experiments|performed the statistical analyses|wrote the manuscript	performed the statistical analyses	Analyzed the data	Formal analysis	YES
4083353	25002835	LS	PLoS52	designed the experiments|performed the experiments|performed the statistical analyses|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4083353	25002835	SC	PLoS52	designed the experiments|performed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
4083353	25002835	SC	PLoS52	designed the experiments|performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5604158	28923004	AB	PLoS52	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5604158	28923004	AK	PLoS52	analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
5604158	28923004	BM	PLoS52	designed the study|analysed the data|edited the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5604158	28923004	BM	PLoS52	designed the study|analysed the data|edited the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
5604158	28923004	BM	PLoS52	designed the study|analysed the data|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5604158	28923004	CVF	PLoS52	designed the study|performed the experiments|analysed the data|edited the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5604158	28923004	CVF	PLoS52	designed the study|performed the experiments|analysed the data|edited the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5604158	28923004	CVF	PLoS52	designed the study|performed the experiments|analysed the data|edited the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
5604158	28923004	CVF	PLoS52	designed the study|performed the experiments|analysed the data|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5604158	28923004	EL	PLoS52	performed the experiments|analysed the data|edited the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5604158	28923004	EL	PLoS52	performed the experiments|analysed the data|edited the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
5604158	28923004	EL	PLoS52	performed the experiments|analysed the data|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5604158	28923004	EM	PLoS52	analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
5604158	28923004	ET	PLoS52	analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
5604158	28923004	FM	PLoS52	designed the study|edited the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5604158	28923004	FM	PLoS52	designed the study|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5604158	28923004	JR	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5604158	28923004	SO	PLoS52	designed the study|edited the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5604158	28923004	SO	PLoS52	designed the study|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5604158	28923004	YD	PLoS52	designed the study|performed the experiments|analysed the data|edited the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5604158	28923004	YD	PLoS52	designed the study|performed the experiments|analysed the data|edited the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5604158	28923004	YD	PLoS52	designed the study|performed the experiments|analysed the data|edited the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
5604158	28923004	YD	PLoS52	designed the study|performed the experiments|analysed the data|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5732145	29321787	BL	2	designed the experiment|helped in interpreting the results and revised the manuscript	designed the experiment	Conceived and designed the experiments	Methodology	YES
5732145	29321787	BL	2	designed the experiment|helped in interpreting the results and revised the manuscript	helped in interpreting the results and revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5732145	29321787	BW	2	performed ssr polymorphism detection	performed ssr polymorphism detection	Performed the experiments	Investigation	YES
5732145	29321787	HJ	2	designed the experiment|helped in interpreting the results and revised the manuscript	designed the experiment	Conceived and designed the experiments	Methodology	YES
5732145	29321787	HJ	2	designed the experiment|helped in interpreting the results and revised the manuscript	helped in interpreting the results and revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5732145	29321787	HL	2	helped in interpreting the results and revised the manuscript	helped in interpreting the results and revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5732145	29321787	JZ	2	performed ssr genotyping in the mapping population|assessed the population structure, relative kinship and linkage disequilibrium level in the peanut panel, and performed association analysis|wrote the manuscript	performed ssr genotyping in the mapping population	Performed the experiments	Investigation	YES
5732145	29321787	JZ	2	performed ssr genotyping in the mapping population|assessed the population structure, relative kinship and linkage disequilibrium level in the peanut panel, and performed association analysis|wrote the manuscript	assessed the population structure, relative kinship and linkage disequilibrium level in the peanut panel, and performed association analysis	Performed the experiments	Investigation	YES
5732145	29321787	JZ	2	performed ssr genotyping in the mapping population|assessed the population structure, relative kinship and linkage disequilibrium level in the peanut panel, and performed association analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5732145	29321787	LH	2	performed seed-related traits evaluation in the mapping population|assessed the population structure, relative kinship and linkage disequilibrium level in the peanut panel, and performed association analysis|wrote the manuscript	performed seed-related traits evaluation in the mapping population	Performed the experiments	Investigation	YES
5732145	29321787	LH	2	performed seed-related traits evaluation in the mapping population|assessed the population structure, relative kinship and linkage disequilibrium level in the peanut panel, and performed association analysis|wrote the manuscript	assessed the population structure, relative kinship and linkage disequilibrium level in the peanut panel, and performed association analysis	Performed the experiments	Investigation	YES
5732145	29321787	LH	2	performed seed-related traits evaluation in the mapping population|assessed the population structure, relative kinship and linkage disequilibrium level in the peanut panel, and performed association analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5732145	29321787	MP	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5732145	29321787	RV	2	helped in interpreting the results and revised the manuscript	helped in interpreting the results and revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5732145	29321787	WC	2	performed seed-related traits evaluation in the mapping population	performed seed-related traits evaluation in the mapping population	Performed the experiments	Investigation	YES
5732145	29321787	XR	2	planted the mapping population|performed seed-related traits evaluation in the mapping population	planted the mapping population	Performed the experiments	Investigation	YES
5732145	29321787	XR	2	planted the mapping population|performed seed-related traits evaluation in the mapping population	performed seed-related traits evaluation in the mapping population	Performed the experiments	Investigation	YES
5732145	29321787	XZ	2	performed seed-related traits evaluation in the mapping population	performed seed-related traits evaluation in the mapping population	Performed the experiments	Investigation	YES
5732145	29321787	YC	2	performed seed-related traits evaluation in the mapping population	performed seed-related traits evaluation in the mapping population	Performed the experiments	Investigation	YES
5732145	29321787	YL	2	helped in interpreting the results and revised the manuscript	helped in interpreting the results and revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5732145	29321787	YX	2	planted the mapping population|performed seed-related traits evaluation in the mapping population	planted the mapping population	Performed the experiments	Investigation	YES
5732145	29321787	YX	2	planted the mapping population|performed seed-related traits evaluation in the mapping population	performed seed-related traits evaluation in the mapping population	Performed the experiments	Investigation	YES
5732145	29321787	ZL	2	performed ssr genotyping in the mapping population	performed ssr genotyping in the mapping population	Performed the experiments	Investigation	YES
4414523	25923652	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414523	25923652	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414523	25923652	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414523	25923652	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414523	25923652	EI	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414523	25923652	EI	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414523	25923652	EI	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414523	25923652	ES	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414523	25923652	ES	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414523	25923652	ES	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414523	25923652	ES	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414523	25923652	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414523	25923652	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414523	25923652	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414523	25923652	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414523	25923652	NP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414523	25923652	NP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414523	25923652	NP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414523	25923652	NP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414523	25923652	NP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1895919	17611628	BJ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1895919	17611628	CJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1895919	17611628	CJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1895919	17611628	CJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1895919	17611628	JK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1895919	17611628	TK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1895919	17611628	TK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1895919	17611628	TK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1895919	17611628	TK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4085729	25006332	LJM	2	made substantial contributions to the acquisition of the data	made substantial contributions to the acquisition of the data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4085729	25006332	LSM	2	contributed to the analysis and interpretation of the data as well as the critical revision and final approval of the manuscript	contributed to the analysis and interpretation of the data as well as the critical revision and final approval of the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
4085729	25006332	YS	2	contributed to the conception, design, analysis, and interpretation of the data	contributed to the conception, design, analysis, and interpretation of the data	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Resources	YES
4609390	26504822	Blanca Humanes	2	contributed equally to this work	contributed equally to this work	-	-	NO
4609390	26504822	Juan Carlos Jado	2	contributed equally to this work	contributed equally to this work	-	-	NO
4609390	26504822	Sonia Camano	2	contributed equally to this work	contributed equally to this work	-	-	NO
4414524	25923779	AC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414524	25923779	AC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414524	25923779	AC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414524	25923779	AC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414524	25923779	AC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414524	25923779	AM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414524	25923779	AM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414524	25923779	AM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414524	25923779	AX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414524	25923779	AX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414524	25923779	AX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414524	25923779	AX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414524	25923779	BK	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414524	25923779	BK	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4414524	25923779	CW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414524	25923779	CW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4414524	25923779	CW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4414524	25923779	CW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414524	25923779	DL	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414524	25923779	DL	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4414524	25923779	DP	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414524	25923779	DP	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4414524	25923779	JB	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414524	25923779	JB	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414524	25923779	JD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414524	25923779	JD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4414524	25923779	JD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4414524	25923779	JD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414524	25923779	KF	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414524	25923779	NB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414524	25923779	NB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414524	25923779	NB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414524	25923779	PV	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414524	25923779	PV	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4414524	25923779	SM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414524	25923779	SM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414524	25923779	SM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414524	25923779	SN	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414524	25923779	SN	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4414524	25923779	SO	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414524	25923779	SO	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414524	25923779	SP	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414524	25923779	SP	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4414524	25923779	VK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414524	25923779	VK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4414524	25923779	VK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5732147	29321788	DC	PLoS52	designed the experiments and wrote the manuscript	designed the experiments and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5732147	29321788	GW	PLoS52	assisted doing the experiment	assisted doing the experiment	Performed the experiments	Investigation	YES
5732147	29321788	JW	PLoS52	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5732147	29321788	SP	PLoS52	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5732147	29321788	XT	PLoS52	assisted doing the experiment	assisted doing the experiment	Performed the experiments	Investigation	YES
5732147	29321788	XZ	PLoS52	designed the experiments and wrote the manuscript	designed the experiments and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5732147	29321788	YC	PLoS52	helped to draft the manuscript	helped to draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5732147	29321788	YL	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5732147	29321788	ZD	PLoS52	helped to draft the manuscript	helped to draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5732147	29321788	ZZ	PLoS52	assisted doing the experiment	assisted doing the experiment	Performed the experiments	Investigation	YES
1895920	17611629	JT	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1895920	17611629	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1895920	17611629	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1895920	17611629	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1895920	17611629	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1895920	17611629	PH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1895920	17611629	PH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1895920	17611629	PH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1895920	17611629	PH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1895920	17611629	PH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1895920	17611629	PT	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1895920	17611629	RM	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1895920	17611629	VW	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1895920	17611629	XG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1895920	17611629	XG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1895920	17611629	XG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5604164	28923001	AP	2	contributed to the data analysis and to the writing of the manuscript	contributed to the data analysis and to the writing of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5604164	28923001	All authors	2	read, critically discussed and approved the final manuscript	read, critically discussed and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5604164	28923001	FA	2	contributed to the data analysis and to the writing of the manuscript	contributed to the data analysis and to the writing of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5604164	28923001	LV	2	performed the search and analysis of data and was a major contributor in writing the manuscript	performed the search and analysis of data and was a major contributor in writing the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5604164	28923001	MC	2	contributed to the search and analysis of data and to the writing of the manuscript, performed the experimental validation of data and coordinated the work	contributed to the search and analysis of data and to the writing of the manuscript, performed the experimental validation of data and coordinated the work	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Project administration|Resources|Validation|Writing - Original Draft	YES
5604164	28923001	MCP	2	contributed to the data analysis and to the writing of the manuscript|reviewed the data analysis	contributed to the data analysis and to the writing of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5604164	28923001	MCP	2	contributed to the data analysis and to the writing of the manuscript|reviewed the data analysis	reviewed the data analysis	Analyzed the data	Formal analysis	YES
5604164	28923001	PS	2	contributed to the search and analysis of data and to the writing of the manuscript	contributed to the search and analysis of data and to the writing of the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
4086998	25006331	All authors	2	have given approval to the final version of the manuscript	have given approval to the final version of the manuscript	-	-	NO
5001960	27566648	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5001960	27566648	All the authors	2	participated in the design of the study	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
5001960	27566648	EvN	2	wrote the manuscript and all the authors critically read and approved the manuscript	wrote the manuscript and all the authors critically read and approved the manuscript	Wrote the paper	Writing - Original Draft	YES
5001960	27566648	VN	2	performed the experimental work|wrote the manuscript and all the authors critically read and approved the manuscript	performed the experimental work	Performed the experiments	Investigation	YES
5001960	27566648	VN	2	performed the experimental work|wrote the manuscript and all the authors critically read and approved the manuscript	wrote the manuscript and all the authors critically read and approved the manuscript	Wrote the paper	Writing - Original Draft	YES
5001960	27566648	VSN	2	performed the experimental work	performed the experimental work	Performed the experiments	Investigation	YES
6082748	30091088	All authors	2	participated in the study design, revised the manuscript, and approved the final manuscript	participated in the study design, revised the manuscript, and approved the final manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
6082748	30091088	CS	2	performed the radiochemical work	performed the radiochemical work	Performed the experiments	Investigation	YES
6082748	30091088	JN	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
6082748	30091088	JS	2	performed the radiochemical work|drafted the manuscript	performed the radiochemical work	Performed the experiments	Investigation	YES
6082748	30091088	JS	2	performed the radiochemical work|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
6082748	30091088	PH	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4414525	25923768	BXF	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4414525	25923768	BXF	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414525	25923768	HNX	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4414525	25923768	HNX	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414525	25923768	HRZ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414525	25923768	HRZ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414525	25923768	HRZ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414525	25923768	HRZ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414525	25923768	LG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414525	25923768	LG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414525	25923768	LG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414525	25923768	MFL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Performed cytology and results classification	Performed the experiments	Performed the experiments	Investigation	YES
4414525	25923768	MFL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Performed cytology and results classification	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414525	25923768	MFL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Performed cytology and results classification	Performed cytology and results classification	Performed the experiments	Investigation	YES
4414525	25923768	XWL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4414525	25923768	XWL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414525	25923768	YY	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4414525	25923768	YY	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414525	25923768	ZL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Performed cytology and results classification	Performed the experiments	Performed the experiments	Investigation	YES
4414525	25923768	ZL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Performed cytology and results classification	Analyzed the data	Analyzed the data	Formal analysis	YES
4414525	25923768	ZL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Performed cytology and results classification	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414525	25923768	ZL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Performed cytology and results classification	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414525	25923768	ZL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Performed cytology and results classification	Performed cytology and results classification	Performed the experiments	Investigation	YES
5732184	29321786	CK	2	designed the experiments and interpreted the results|supervised the project and complemented the writing	designed the experiments and interpreted the results	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5732184	29321786	CK	2	designed the experiments and interpreted the results|supervised the project and complemented the writing	supervised the project and complemented the writing	Wrote the paper	Supervision	YES
5732184	29321786	DY	2	carried out the experiments and interpreted the results	carried out the experiments and interpreted the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5732184	29321786	H-WJ	2	carried out the experiments and interpreted the results	carried out the experiments and interpreted the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5732184	29321786	J-HM	2	designed the experiments and interpreted the results|carried out the experiments and interpreted the results	designed the experiments and interpreted the results	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5732184	29321786	J-HM	2	designed the experiments and interpreted the results|carried out the experiments and interpreted the results	carried out the experiments and interpreted the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5732184	29321786	K-HL	2	carried out the experiments and interpreted the results	carried out the experiments and interpreted the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5732184	29321786	SL	2	provided technical assistance with the emsa analysis	provided technical assistance with the emsa analysis	Performed the experiments	Investigation	YES
1895921	17611621	JT	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1895921	17611621	LL	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1895921	17611621	LL	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1895921	17611621	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1895921	17611621	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1895921	17611621	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1895921	17611621	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1895921	17611621	MN	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1895921	17611621	MN	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1895921	17611621	MN	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1895921	17611621	NL	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1895921	17611621	NL	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1895921	17611621	WY	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1895921	17611621	WY	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1895921	17611621	YW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1895921	17611621	YW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1895921	17611621	YW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1895921	17611621	YW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6093825	30112704	CL	2	designed the animal studies, analyzed the data, and wrote the manuscript	designed the animal studies, analyzed the data, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
6093825	30112704	IM	2	designed the animal studies, analyzed the data, and wrote the manuscript	designed the animal studies, analyzed the data, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
6093825	30112704	KW	2	performed the experiments, analyzed the data, and wrote the manuscript	performed the experiments, analyzed the data, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6093825	30112704	LH	2	performed the experiments, analyzed the data, and wrote the manuscript	performed the experiments, analyzed the data, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6093825	30112704	MD	2	designed the animal studies, analyzed the data, and wrote the manuscript	designed the animal studies, analyzed the data, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
6093825	30112704	MM	2	designed the animal studies, analyzed the data, and wrote the manuscript	designed the animal studies, analyzed the data, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
6093825	30112704	MS	2	designed the animal studies, analyzed the data, and wrote the manuscript	designed the animal studies, analyzed the data, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
6093825	30112704	NB	2	performed the experiments, analyzed the data, and wrote the manuscript	performed the experiments, analyzed the data, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6093825	30112704	SP	2	performed the experiments, analyzed the data, and wrote the manuscript|designed the animal studies, analyzed the data, and wrote the manuscript	performed the experiments, analyzed the data, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6093825	30112704	SP	2	performed the experiments, analyzed the data, and wrote the manuscript|designed the animal studies, analyzed the data, and wrote the manuscript	designed the animal studies, analyzed the data, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
6093825	30112704	US	2	designed the animal studies, analyzed the data, and wrote the manuscript	designed the animal studies, analyzed the data, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4609392	26504840	Yijun Li	2	equally contributed to the paper	equally contributed to the paper	-	-	NO
4609392	26504840	Yiming Mu	2	equally contributed to the paper	equally contributed to the paper	-	-	NO
4094671	25050085	HH	2	analysed data	analysed data	Analyzed the data	Formal analysis	YES
4094671	25050085	HS	2	interpreted the data	interpreted the data	Analyzed the data	Formal analysis	YES
4094671	25050085	HY	2	analysed data	analysed data	Analyzed the data	Formal analysis	YES
4094671	25050085	JK	2	analysed and interpreted the data and wrote the manuscript	analysed and interpreted the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4094671	25050085	JP	2	interpreted the data and wrote the manuscript	interpreted the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4094671	25050085	KL	2	interpreted the data and had primary responsibility for the final content	interpreted the data and had primary responsibility for the final content	Analyzed the data	Formal analysis	YES
5002273	27568226	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5002273	27568226	CYP	PLoS52	provided the rice straw holocellulose	provided the rice straw holocellulose	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5002273	27568226	HBH	PLoS52	reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5002273	27568226	Professor Song	PLoS52	of shandong university for providing the strain	of shandong university for providing the strain	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5002273	27568226	RSY	PLoS52	conceived and designed the study|reviewed and edited the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5002273	27568226	RSY	PLoS52	conceived and designed the study|reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5002273	27568226	The authors	PLoS52	declare that they have no competing interests|claim that none of the material in the paper has been published or is under consideration for publication elsewhere	declare that they have no competing interests	-	-	NO
5002273	27568226	The authors	PLoS52	declare that they have no competing interests|claim that none of the material in the paper has been published or is under consideration for publication elsewhere	claim that none of the material in the paper has been published or is under consideration for publication elsewhere	-	-	NO
5002273	27568226	XGL	PLoS52	performed the experiments|write the paper	performed the experiments	Performed the experiments	Investigation	YES
5002273	27568226	XGL	PLoS52	performed the experiments|write the paper	write the paper	Wrote the paper	Writing - Original Draft	YES
5002273	27568226	XJM	PLoS52	conceived and designed the study|reviewed and edited the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5002273	27568226	XJM	PLoS52	conceived and designed the study|reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
3839125	24311978	Bronwen Rhodes	2	participated in the designing of the study and the writing of the paper	participated in the designing of the study and the writing of the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3839125	24311978	Lutz Beckert	2	participated in the designing of the study, the data analyses, and writing of the paper	participated in the designing of the study, the data analyses, and writing of the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3839125	24311978	Nick Erskine	2	participated in the data collection, data analyses, and writing of the paper	participated in the data collection, data analyses, and writing of the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3839125	24311978	Sue Stevenson	2	participated in the designing of the study and the data analyses	participated in the designing of the study and the data analyses	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
3839125	24311978	Vivien Daley	2	participated in the designing of the study, the data analyses, and the writing of the paper	participated in the designing of the study, the data analyses, and the writing of the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
1899087	17611620	AA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1899087	17611620	AA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1899087	17611620	AA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1899087	17611620	AA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1899087	17611620	MM	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1899087	17611620	PJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1899087	17611620	PJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1899087	17611620	PJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1899087	17611620	RD	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5732185	29321785	AW	2	conceived and designed the research|conducted the experiments|analyzed the data and wrote the manuscript	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5732185	29321785	AW	2	conceived and designed the research|conducted the experiments|analyzed the data and wrote the manuscript	conducted the experiments	Performed the experiments	Investigation	YES
5732185	29321785	AW	2	conceived and designed the research|conducted the experiments|analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5732185	29321785	All the authors	2	read and approved the manuscript	read and approved the manuscript	-	-	NO
5732185	29321785	MG	2	conceived and designed the research|analyzed the data and wrote the manuscript	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5732185	29321785	MG	2	conceived and designed the research|analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5732185	29321785	MN	2	provided the wish of mirna	provided the wish of mirna	-	-	NO
4414529	25923434	BP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414529	25923434	BP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414529	25923434	BP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414529	25923434	BP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414529	25923434	BP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414529	25923434	CB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414529	25923434	CB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414529	25923434	CB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414529	25923434	CB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414529	25923434	CB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414529	25923434	EAG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414529	25923434	EAG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414529	25923434	EAG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414529	25923434	EAG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414529	25923434	RC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414529	25923434	RC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414529	25923434	RC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414529	25923434	RC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414529	25923434	XDL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414529	25923434	XDL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414529	25923434	XDL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414529	25923434	XDL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5604286	28923019	BL	2	participated in data analysis and the manuscript preparation	participated in data analysis and the manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5604286	28923019	JY	2	analyzed the data and prepared the manuscript	analyzed the data and prepared the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5604286	28923019	KD	2	participated in data analysis and the manuscript preparation	participated in data analysis and the manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5604286	28923019	LW	2	participated in data analysis and the manuscript preparation	participated in data analysis and the manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5604286	28923019	ST	2	participated in data analysis and the manuscript preparation	participated in data analysis and the manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5604286	28923019	TK	2	participated in data analysis and the manuscript preparation	participated in data analysis and the manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5604286	28923019	XZ	2	participated in data analysis and the manuscript preparation	participated in data analysis and the manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4105559	25053925	AH	2	statistical analysis, data collection and interpretation and manuscript preparation	statistical analysis, data collection and interpretation and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4105559	25053925	HG	2	made substantial contributions to the study design, statistical analysis, data collection and interpretation and manuscript preparation	made substantial contributions to the study design, statistical analysis, data collection and interpretation and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
4105559	25053925	KB	2	made substantial contributions to the study design, statistical analysis, data collection and interpretation and manuscript preparation	made substantial contributions to the study design, statistical analysis, data collection and interpretation and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
4105559	25053925	TL	2	made substantial contributions to the study design, statistical analysis, data interpretation and manuscript preparation	made substantial contributions to the study design, statistical analysis, data interpretation and manuscript preparation	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Original Draft	YES
1899224	17622342	AK	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1899224	17622342	AK	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1899224	17622342	BK	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1899224	17622342	CK	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1899224	17622342	DW	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1899224	17622342	DW	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1899224	17622342	IM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1899224	17622342	IM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1899224	17622342	IM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6093830	30112620	AAL	2	contributed to the conception and design, analyzed and interpreted the data, drafted the manuscript and enhanced its intellectual content, and approved the final content of the manuscript	contributed to the conception and design, analyzed and interpreted the data, drafted the manuscript and enhanced its intellectual content, and approved the final content of the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Resources|Writing - Original Draft	YES
6093830	30112620	ADW	2	contributed to the conception and design, enhanced its intellectual content, and approved the final content of the manuscript	contributed to the conception and design, enhanced its intellectual content, and approved the final content of the manuscript	Conceived and designed the experiments	Conceptualization	YES
6093830	30112620	BNMvB	2	contributed to the conception and design, analyzed and interpreted the data, drafted the manuscript and enhanced its intellectual content, and approved the final content of the manuscript	contributed to the conception and design, analyzed and interpreted the data, drafted the manuscript and enhanced its intellectual content, and approved the final content of the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Resources|Writing - Original Draft	YES
6093830	30112620	CWJvdW	2	analyzed and interpreted the data, critically revised the manuscript, and approved the final content of the manuscript	analyzed and interpreted the data, critically revised the manuscript, and approved the final content of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
6093830	30112620	EEW	2	acquired the data, analyzed and interpreted the data, drafted the manuscript, and approved the final content of the manuscript	acquired the data, analyzed and interpreted the data, drafted the manuscript, and approved the final content of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6093830	30112620	FB	2	contributed to the conception and design, analyzed and interpreted the data, drafted the manuscript and enhanced its intellectual content, and approved the final content of the manuscript	contributed to the conception and design, analyzed and interpreted the data, drafted the manuscript and enhanced its intellectual content, and approved the final content of the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Resources|Writing - Original Draft	YES
6093830	30112620	LS	2	acquired the data, critically revised the manuscript, and approved the final content of the manuscript	acquired the data, critically revised the manuscript, and approved the final content of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
6093830	30112620	MY	2	contributed to the conception and design, analyzed and interpreted the data, drafted the manuscript and enhanced its intellectual content, and approved the final content of the manuscript	contributed to the conception and design, analyzed and interpreted the data, drafted the manuscript and enhanced its intellectual content, and approved the final content of the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Resources|Writing - Original Draft	YES
6093830	30112620	PS	2	contributed to the conception and design, enhanced its intellectual content, and approved the final content of the manuscript	contributed to the conception and design, enhanced its intellectual content, and approved the final content of the manuscript	Conceived and designed the experiments	Conceptualization	YES
6093830	30112620	RB	2	contributed to the conception and design, analyzed and interpreted the data, drafted the manuscript and enhanced its intellectual content, and approved the final content of the manuscript	contributed to the conception and design, analyzed and interpreted the data, drafted the manuscript and enhanced its intellectual content, and approved the final content of the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Resources|Writing - Original Draft	YES
6093830	30112620	RCS	2	acquired the data, analyzed and interpreted the data, critically contributed to the manuscript, and approved the final content of the manuscript	acquired the data, analyzed and interpreted the data, critically contributed to the manuscript, and approved the final content of the manuscript	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6093830	30112620	RO	2	contributed to the conception and design, enhanced its intellectual content, and approved the final content of the manuscript	contributed to the conception and design, enhanced its intellectual content, and approved the final content of the manuscript	Conceived and designed the experiments	Conceptualization	YES
6093830	30112620	SSVG	2	acquired the data, analyzed and interpreted the data, drafted the manuscript, and approved the final content of the manuscript	acquired the data, analyzed and interpreted the data, drafted the manuscript, and approved the final content of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6093830	30112620	TT	2	acquired the data, critically revised the manuscript, and approved the final content of the manuscript	acquired the data, critically revised the manuscript, and approved the final content of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4414530	25924009	BM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed to the writing of the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414530	25924009	BM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed to the writing of the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4414530	25924009	BM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed to the writing of the manuscript	Contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
4414530	25924009	CKO	PLoS5	Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Contributed to the writing of the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414530	25924009	CKO	PLoS5	Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Contributed to the writing of the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414530	25924009	CKO	PLoS5	Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Contributed to the writing of the manuscript	Contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
4414530	25924009	DLP	PLoS5	Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Contributed to the writing of the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414530	25924009	DLP	PLoS5	Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Contributed to the writing of the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414530	25924009	DLP	PLoS5	Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Contributed to the writing of the manuscript	Contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
4414530	25924009	JAP	PLoS5	Contributed reagents/materials/analysis tools|Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Contributed to the writing of the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414530	25924009	JAP	PLoS5	Contributed reagents/materials/analysis tools|Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Contributed to the writing of the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414530	25924009	JAP	PLoS5	Contributed reagents/materials/analysis tools|Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Contributed to the writing of the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4414530	25924009	JAP	PLoS5	Contributed reagents/materials/analysis tools|Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Contributed to the writing of the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414530	25924009	JAP	PLoS5	Contributed reagents/materials/analysis tools|Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Contributed to the writing of the manuscript	Contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
4414530	25924009	LTW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed to the writing of the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414530	25924009	LTW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed to the writing of the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4414530	25924009	LTW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed to the writing of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4414530	25924009	LTW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed to the writing of the manuscript	Contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
4414530	25924009	Margaret S. Coleman	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed to the writing of the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414530	25924009	Margaret S. Coleman	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed to the writing of the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4414530	25924009	Margaret S. Coleman	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed to the writing of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4414530	25924009	Margaret S. Coleman	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed to the writing of the manuscript	Contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
4414530	25924009	Martin S. Cetron	PLoS5	Conceived and designed the experiments|Contributed to the writing of the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414530	25924009	Martin S. Cetron	PLoS5	Conceived and designed the experiments|Contributed to the writing of the manuscript	Contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
4414530	25924009	WZ	PLoS5	Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Contributed to the writing of the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414530	25924009	WZ	PLoS5	Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Contributed to the writing of the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414530	25924009	WZ	PLoS5	Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Contributed to the writing of the manuscript	Contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
4107592	25057266	FAA	2	participated in the study design, the statistical analysis and the writing of the manuscript	participated in the study design, the statistical analysis and the writing of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4107592	25057266	FM	2	participated in the study design	participated in the study design	Conceived and designed the experiments	Methodology	YES
4107592	25057266	GD	2	participated in the study design and the writing of the manuscript	participated in the study design and the writing of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4107592	25057266	NB	2	was responsible for the study design, the execution of the measurements and the writing of the manuscript	was responsible for the study design, the execution of the measurements and the writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
4107592	25057266	PLR	2	participated in the study design	participated in the study design	Conceived and designed the experiments	Methodology	YES
5732187	29321789	CK	2	did and interpreted the synchrotron mid-ir analysis|participated in writing the manuscript	did and interpreted the synchrotron mid-ir analysis	Analyzed the data	Formal analysis	YES
5732187	29321789	CK	2	did and interpreted the synchrotron mid-ir analysis|participated in writing the manuscript	participated in writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5732187	29321789	JO	2	devised and participated in all aspects of the studies including designing of the experiments, statistical analyses and interpretation of the results|participated in writing the manuscript	devised and participated in all aspects of the studies including designing of the experiments, statistical analyses and interpretation of the results	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation|Methodology	YES
5732187	29321789	JO	2	devised and participated in all aspects of the studies including designing of the experiments, statistical analyses and interpretation of the results|participated in writing the manuscript	participated in writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5732187	29321789	KT	2	coordinated the synchrotron mid-ir analysis and discussed experiments|participated in writing the manuscript	coordinated the synchrotron mid-ir analysis and discussed experiments	-	Project administration	YES
5732187	29321789	KT	2	coordinated the synchrotron mid-ir analysis and discussed experiments|participated in writing the manuscript	participated in writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5732187	29321789	RL	2	did and interpreted the synchrotron mid-ir analysis	did and interpreted the synchrotron mid-ir analysis	Analyzed the data	Formal analysis	YES
5732187	29321789	XL	2	did and interpreted the synchrotron mid-ir analysis	did and interpreted the synchrotron mid-ir analysis	Analyzed the data	Formal analysis	YES
5732187	29321789	YL	2	devised and participated in all aspects of the studies including designing of the experiments, statistical analyses and interpretation of the results|contributed to growing plants and harvested the materials, performed microscopy studies, and participated in the synchrotron mid-ir analysis|participated in writing the manuscript	devised and participated in all aspects of the studies including designing of the experiments, statistical analyses and interpretation of the results	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation|Methodology	YES
5732187	29321789	YL	2	devised and participated in all aspects of the studies including designing of the experiments, statistical analyses and interpretation of the results|contributed to growing plants and harvested the materials, performed microscopy studies, and participated in the synchrotron mid-ir analysis|participated in writing the manuscript	contributed to growing plants and harvested the materials, performed microscopy studies, and participated in the synchrotron mid-ir analysis	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5732187	29321789	YL	2	devised and participated in all aspects of the studies including designing of the experiments, statistical analyses and interpretation of the results|contributed to growing plants and harvested the materials, performed microscopy studies, and participated in the synchrotron mid-ir analysis|participated in writing the manuscript	participated in writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5005231	27576895	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5005231	27576895	BA	2	contributed to the conception and design of the experiments|performed the experiments, analyzed the data and drafted the manuscript	contributed to the conception and design of the experiments	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
5005231	27576895	BA	2	contributed to the conception and design of the experiments|performed the experiments, analyzed the data and drafted the manuscript	performed the experiments, analyzed the data and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5005231	27576895	CRIS	2	project 5347-42000-019-00d|project 5347-42000-019-00d	project 5347-42000-019-00d	-	-	NO
5005231	27576895	CRIS	2	project 5347-42000-019-00d|project 5347-42000-019-00d	project 5347-42000-019-00d	-	-	NO
5005231	27576895	PC	2	contributed to the conception and design of the experiments	contributed to the conception and design of the experiments	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
5005231	27576895	RB	2	contributed to the conception and design of the experiments	contributed to the conception and design of the experiments	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
5005231	27576895	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5604411	28923009	AC	1	The manuscript was written and edited by	The manuscript was written and edited by	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5604411	28923009	AKG	1	The manuscript was written and edited by	The manuscript was written and edited by	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5604411	28923009	CB	1	The experiments were performed and analysed by|The manuscript was written and edited by	The experiments were performed and analysed by	Performed the experiments	Investigation	YES
5604411	28923009	CB	1	The experiments were performed and analysed by|The manuscript was written and edited by	The manuscript was written and edited by	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5604411	28923009	GSP	1	The manuscript was written and edited by	The manuscript was written and edited by	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5604411	28923009	HP	1	The experiments were performed and analysed by|The manuscript was written and edited by	The experiments were performed and analysed by	Performed the experiments	Investigation	YES
5604411	28923009	HP	1	The experiments were performed and analysed by|The manuscript was written and edited by	The manuscript was written and edited by	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5604411	28923009	MK	1	The experiments were performed and analysed by|The manuscript was written and edited by	The experiments were performed and analysed by	Performed the experiments	Investigation	YES
5604411	28923009	MK	1	The experiments were performed and analysed by|The manuscript was written and edited by	The manuscript was written and edited by	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5604411	28923009	SMR	1	The experiments were performed and analysed by|The manuscript was written and edited by	The experiments were performed and analysed by	Performed the experiments	Investigation	YES
5604411	28923009	SMR	1	The experiments were performed and analysed by|The manuscript was written and edited by	The manuscript was written and edited by	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4120730	25093015	AWK	2	assisted data collection and analysis and manuscript preparation	assisted data collection and analysis and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4120730	25093015	DAB	2	assisted data collection and analysis and manuscript preparation	assisted data collection and analysis and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4120730	25093015	DT	2	assisted data collection and analysis and manuscript preparation	assisted data collection and analysis and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4120730	25093015	MEE	2	assisted data collection and analysis and manuscript preparation	assisted data collection and analysis and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4120730	25093015	MJO	2	designed and managed the study, secured funding, analyzed the data and drafted the manuscript	designed and managed the study, secured funding, analyzed the data and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Data curation|Formal analysis|Funding acquisition|Methodology|Project administration|Writing - Original Draft	YES
4120730	25093015	MTS	2	assisted with study design and manuscript preparation	assisted with study design and manuscript preparation	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4120730	25093015	NF	2	assisted data collection and analysis and manuscript preparation	assisted data collection and analysis and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4120730	25093015	SRR	2	carried out all practical aspects of the study and assisted with data analysis, and manuscript preparation	carried out all practical aspects of the study and assisted with data analysis, and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4120730	25093015	TAM	2	assisted data collection and analysis and manuscript preparation	assisted data collection and analysis and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
1899225	17622345	CF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1899225	17622345	CF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1899225	17622345	CF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1899225	17622345	CF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1899225	17622345	DB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1899225	17622345	DB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1899225	17622345	FW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1899225	17622345	FW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1899225	17622345	FW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1899225	17622345	JP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1899225	17622345	JP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1899225	17622345	TT	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1899225	17622345	TT	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1899225	17622345	TT	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5732193	29312374	DH	2	jointly conceived the study, acquired and interpreted the data, wrote the manuscript and assisted with manuscript revision	jointly conceived the study, acquired and interpreted the data, wrote the manuscript and assisted with manuscript revision	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5732193	29312374	JC	2	acquired and analyzed data and commented on the manuscript	acquired and analyzed data and commented on the manuscript	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5732193	29312374	JT	2	acquired and analyzed data and commented on the manuscript	acquired and analyzed data and commented on the manuscript	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5732193	29312374	PD	2	jointly conceived the study, acquired and interpreted the data, wrote the manuscript and assisted with manuscript revision	jointly conceived the study, acquired and interpreted the data, wrote the manuscript and assisted with manuscript revision	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5732193	29312374	RJ	2	jointly conceived the study, acquired and interpreted the data, wrote the manuscript and assisted with manuscript revision	jointly conceived the study, acquired and interpreted the data, wrote the manuscript and assisted with manuscript revision	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
4414531	25923737	AW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414531	25923737	AW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414531	25923737	AW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414531	25923737	AW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414531	25923737	AW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414531	25923737	HN	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414531	25923737	HN	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414531	25923737	HN	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414531	25923737	HN	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414531	25923737	IRK	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414531	25923737	IRK	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414531	25923737	IRK	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414531	25923737	IRK	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414531	25923737	JDC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414531	25923737	JDC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414531	25923737	JDC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414531	25923737	JDC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414531	25923737	JDC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414531	25923737	JP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414531	25923737	JP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414531	25923737	JP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414531	25923737	JP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414531	25923737	JP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414531	25923737	MGH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414531	25923737	MGH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414531	25923737	MGH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414531	25923737	MGH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414531	25923737	OW	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414531	25923737	OW	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414531	25923737	OW	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414531	25923737	OW	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414531	25923737	PJN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414531	25923737	PJN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414531	25923737	PJN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414531	25923737	PJN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414531	25923737	SG	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414531	25923737	SG	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414531	25923737	SG	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414531	25923737	SG	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6095934	30116910	DA	2	performed the rat studies|analyzed and interpreted the pet data|wrote the manuscript	performed the rat studies	Performed the experiments	Investigation	YES
6095934	30116910	DA	2	performed the rat studies|analyzed and interpreted the pet data|wrote the manuscript	analyzed and interpreted the pet data	Analyzed the data	Formal analysis	YES
6095934	30116910	DA	2	performed the rat studies|analyzed and interpreted the pet data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6095934	30116910	FC	2	performed the radiochemical production	performed the radiochemical production	Performed the experiments	Investigation	YES
6095934	30116910	MB	2	designed the study|critically revised the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
6095934	30116910	MB	2	designed the study|critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
6095934	30116910	NT	2	designed the study|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
6095934	30116910	NT	2	designed the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6095934	30116910	OL	2	designed the study|critically revised the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
6095934	30116910	OL	2	designed the study|critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
6095934	30116910	SA	2	performed the rat studies|analyzed and interpreted the pet data|designed the study|critically revised the manuscript	performed the rat studies	Performed the experiments	Investigation	YES
6095934	30116910	SA	2	performed the rat studies|analyzed and interpreted the pet data|designed the study|critically revised the manuscript	analyzed and interpreted the pet data	Analyzed the data	Formal analysis	YES
6095934	30116910	SA	2	performed the rat studies|analyzed and interpreted the pet data|designed the study|critically revised the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
6095934	30116910	SA	2	performed the rat studies|analyzed and interpreted the pet data|designed the study|critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
6095934	30116910	SG	2	performed the rat studies	performed the rat studies	Performed the experiments	Investigation	YES
6095934	30116910	SM	2	analyzed and interpreted the pet data	analyzed and interpreted the pet data	Analyzed the data	Formal analysis	YES
4609395	26504823	Lisa McStay	2	contributed equally to this work	contributed equally to this work	-	-	NO
4609395	26504823	Xingqiong Meng	2	contributed equally to this work	contributed equally to this work	-	-	NO
4134516	25132809	BSF	2	person has made substantial contributions to conception and design, or acquisition of data, or analysis and interpretation of data|person gave final approval of the version to be published|person agrees to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	person has made substantial contributions to conception and design, or acquisition of data, or analysis and interpretation of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
4134516	25132809	BSF	2	person has made substantial contributions to conception and design, or acquisition of data, or analysis and interpretation of data|person gave final approval of the version to be published|person agrees to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	person gave final approval of the version to be published	-	-	NO
4134516	25132809	BSF	2	person has made substantial contributions to conception and design, or acquisition of data, or analysis and interpretation of data|person gave final approval of the version to be published|person agrees to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	person agrees to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	-	-	NO
4134516	25132809	CBM	2	person primarily was involved in drafting the manuscript or revising it critically for important intellectual content|person gave final approval of the version to be published|person agrees to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	person primarily was involved in drafting the manuscript or revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4134516	25132809	CBM	2	person primarily was involved in drafting the manuscript or revising it critically for important intellectual content|person gave final approval of the version to be published|person agrees to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	person gave final approval of the version to be published	-	-	NO
4134516	25132809	CBM	2	person primarily was involved in drafting the manuscript or revising it critically for important intellectual content|person gave final approval of the version to be published|person agrees to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	person agrees to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	-	-	NO
4134516	25132809	CDF	2	person has made substantial contributions to conception and design, or acquisition of data, or analysis and interpretation of data|person gave final approval of the version to be published|person agrees to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	person has made substantial contributions to conception and design, or acquisition of data, or analysis and interpretation of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
4134516	25132809	CDF	2	person has made substantial contributions to conception and design, or acquisition of data, or analysis and interpretation of data|person gave final approval of the version to be published|person agrees to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	person gave final approval of the version to be published	-	-	NO
4134516	25132809	CDF	2	person has made substantial contributions to conception and design, or acquisition of data, or analysis and interpretation of data|person gave final approval of the version to be published|person agrees to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	person agrees to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	-	-	NO
4134516	25132809	JAR	2	person has made substantial contributions to conception and design, or acquisition of data, or analysis and interpretation of data|person gave final approval of the version to be published|person agrees to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	person has made substantial contributions to conception and design, or acquisition of data, or analysis and interpretation of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
4134516	25132809	JAR	2	person has made substantial contributions to conception and design, or acquisition of data, or analysis and interpretation of data|person gave final approval of the version to be published|person agrees to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	person gave final approval of the version to be published	-	-	NO
4134516	25132809	JAR	2	person has made substantial contributions to conception and design, or acquisition of data, or analysis and interpretation of data|person gave final approval of the version to be published|person agrees to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	person agrees to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	-	-	NO
4134516	25132809	JMW	2	person has made substantial contributions to conception and design, or acquisition of data, or analysis and interpretation of data|person gave final approval of the version to be published|person agrees to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	person has made substantial contributions to conception and design, or acquisition of data, or analysis and interpretation of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
4134516	25132809	JMW	2	person has made substantial contributions to conception and design, or acquisition of data, or analysis and interpretation of data|person gave final approval of the version to be published|person agrees to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	person gave final approval of the version to be published	-	-	NO
4134516	25132809	JMW	2	person has made substantial contributions to conception and design, or acquisition of data, or analysis and interpretation of data|person gave final approval of the version to be published|person agrees to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	person agrees to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	-	-	NO
4134516	25132809	MDR	2	person has made substantial contributions to conception and design, or acquisition of data, or analysis and interpretation of data|person primarily was involved in drafting the manuscript or revising it critically for important intellectual content|person gave final approval of the version to be published|person agrees to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	person has made substantial contributions to conception and design, or acquisition of data, or analysis and interpretation of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
4134516	25132809	MDR	2	person has made substantial contributions to conception and design, or acquisition of data, or analysis and interpretation of data|person primarily was involved in drafting the manuscript or revising it critically for important intellectual content|person gave final approval of the version to be published|person agrees to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	person primarily was involved in drafting the manuscript or revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4134516	25132809	MDR	2	person has made substantial contributions to conception and design, or acquisition of data, or analysis and interpretation of data|person primarily was involved in drafting the manuscript or revising it critically for important intellectual content|person gave final approval of the version to be published|person agrees to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	person gave final approval of the version to be published	-	-	NO
4134516	25132809	MDR	2	person has made substantial contributions to conception and design, or acquisition of data, or analysis and interpretation of data|person primarily was involved in drafting the manuscript or revising it critically for important intellectual content|person gave final approval of the version to be published|person agrees to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	person agrees to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	-	-	NO
4134516	25132809	RHA	2	person has made substantial contributions to conception and design, or acquisition of data, or analysis and interpretation of data|person gave final approval of the version to be published|person agrees to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	person has made substantial contributions to conception and design, or acquisition of data, or analysis and interpretation of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
4134516	25132809	RHA	2	person has made substantial contributions to conception and design, or acquisition of data, or analysis and interpretation of data|person gave final approval of the version to be published|person agrees to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	person gave final approval of the version to be published	-	-	NO
4134516	25132809	RHA	2	person has made substantial contributions to conception and design, or acquisition of data, or analysis and interpretation of data|person gave final approval of the version to be published|person agrees to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	person agrees to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	-	-	NO
4134516	25132809	SB	2	person has made substantial contributions to conception and design, or acquisition of data, or analysis and interpretation of data|person gave final approval of the version to be published|person agrees to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	person has made substantial contributions to conception and design, or acquisition of data, or analysis and interpretation of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
4134516	25132809	SB	2	person has made substantial contributions to conception and design, or acquisition of data, or analysis and interpretation of data|person gave final approval of the version to be published|person agrees to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	person gave final approval of the version to be published	-	-	NO
4134516	25132809	SB	2	person has made substantial contributions to conception and design, or acquisition of data, or analysis and interpretation of data|person gave final approval of the version to be published|person agrees to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	person agrees to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	-	-	NO
4134516	25132809	VJD	2	person has made substantial contributions to conception and design, or acquisition of data, or analysis and interpretation of data|person gave final approval of the version to be published|person agrees to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	person has made substantial contributions to conception and design, or acquisition of data, or analysis and interpretation of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
4134516	25132809	VJD	2	person has made substantial contributions to conception and design, or acquisition of data, or analysis and interpretation of data|person gave final approval of the version to be published|person agrees to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	person gave final approval of the version to be published	-	-	NO
4134516	25132809	VJD	2	person has made substantial contributions to conception and design, or acquisition of data, or analysis and interpretation of data|person gave final approval of the version to be published|person agrees to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	person agrees to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	-	-	NO
5005234	27576894	All	2	applicable international, national, and/or institutional guidelines for the care and use of animals were followed	applicable international, national, and/or institutional guidelines for the care and use of animals were followed	-	-	NO
5005234	27576894	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5005234	27576894	HEN	2	participated in formulating the research questions, study design, organizing funding for the project and preparing the manuscript	participated in formulating the research questions, study design, organizing funding for the project and preparing the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Funding acquisition|Methodology|Project administration|Writing - Original Draft	YES
5005234	27576894	K Chan	2	participated in formulating the research questions, study design, practical laboratory work, analyzing the data and preparing the manuscript	participated in formulating the research questions, study design, practical laboratory work, analyzing the data and preparing the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5005234	27576894	KK	2	participated in the practical laboratory work and analyzing the microbiological data	participated in the practical laboratory work and analyzing the microbiological data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5005234	27576894	PVK	2	participated in formulating the research questions, study design, organizing funding for the microbiological work, analyzing the data and preparing the manuscript	participated in formulating the research questions, study design, organizing funding for the microbiological work, analyzing the data and preparing the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Funding acquisition|Investigation|Methodology|Project administration|Writing - Original Draft	YES
5005234	27576894	Small Grant Fund	2	the university of hong kong	the university of hong kong	-	-	NO
5005234	27576894	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5005234	27576894	YC	2	participated in formulating the research questions, study design and preparing the manuscript	participated in formulating the research questions, study design and preparing the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
1899226	17611623	CK	PLoS5	Implemented the conditional model	Implemented the conditional model	Performed the experiments	Investigation|Methodology	YES
1899226	17611623	DH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1899226	17611623	DH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1899226	17611623	DH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1899226	17611623	JC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1899226	17611623	JC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1899226	17611623	JC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1899226	17611623	JC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5732267	29312371	AL	7	Writing the text, drawing the figures	Writing the text, drawing the figures	Wrote the paper	Visualization	YES
5732267	29312371	KM	7	Writing the text	Writing the text	Wrote the paper	-	YES
5732267	29312371	MP	7	Writing the text, Compiling the tables	Writing the text, Compiling the tables	Wrote the paper	-	YES
5604515	28923029	AD	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5604515	28923029	BB	2	designed the study|wrote the scripts and carried out the analysis	designed the study	Conceived and designed the experiments	Methodology	YES
5604515	28923029	BB	2	designed the study|wrote the scripts and carried out the analysis	wrote the scripts and carried out the analysis	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Software|Writing - Original Draft	YES
5604515	28923029	CW	2	sequenced large part of the strains used for this study	sequenced large part of the strains used for this study	Performed the experiments	Investigation	YES
5604515	28923029	MR	2	sequenced large part of the strains used for this study	sequenced large part of the strains used for this study	Performed the experiments	Investigation	YES
5604515	28923029	PD	2	sequenced large part of the strains used for this study	sequenced large part of the strains used for this study	Performed the experiments	Investigation	YES
5604515	28923029	TAJL	2	sequenced large part of the strains used for this study	sequenced large part of the strains used for this study	Performed the experiments	Investigation	YES
4151021	25183955	MA	2	carried out experimental studies, participated in the randomized assignment of the participants and drafted the manuscript|carried out the immunoassays|participated in the design of the study and performed the statistical analysis|conceived of the study, and participated in its design and coordination and helped to draft the manuscript	carried out experimental studies, participated in the randomized assignment of the participants and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4151021	25183955	MA	2	carried out experimental studies, participated in the randomized assignment of the participants and drafted the manuscript|carried out the immunoassays|participated in the design of the study and performed the statistical analysis|conceived of the study, and participated in its design and coordination and helped to draft the manuscript	carried out the immunoassays	Performed the experiments	Investigation	YES
4151021	25183955	MA	2	carried out experimental studies, participated in the randomized assignment of the participants and drafted the manuscript|carried out the immunoassays|participated in the design of the study and performed the statistical analysis|conceived of the study, and participated in its design and coordination and helped to draft the manuscript	participated in the design of the study and performed the statistical analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
4151021	25183955	MA	2	carried out experimental studies, participated in the randomized assignment of the participants and drafted the manuscript|carried out the immunoassays|participated in the design of the study and performed the statistical analysis|conceived of the study, and participated in its design and coordination and helped to draft the manuscript	conceived of the study, and participated in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
4151021	25183955	The author	2	has read and approved the final manuscript	has read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6095935	30117062	HT	2	carried out pet studies	carried out pet studies	Performed the experiments	Investigation	YES
6095935	30117062	HY	2	carried out pet studies	carried out pet studies	Performed the experiments	Investigation	YES
6095935	30117062	KH	2	carried out pet studies	carried out pet studies	Performed the experiments	Investigation	YES
6095935	30117062	KN	2	carried out pet studies	carried out pet studies	Performed the experiments	Investigation	YES
6095935	30117062	MO	2	conceived of the study, and participated in its design and coordination and helped to draft the manuscript	conceived of the study, and participated in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
6095935	30117062	MT	2	carried out the pet studies, flow cytometry, and data analysis and drafted the manuscript	carried out the pet studies, flow cytometry, and data analysis and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6095935	30117062	TS	2	carried out pet studies	carried out pet studies	Performed the experiments	Investigation	YES
6095935	30117062	YK	2	participated in the design of the study and performed the pet analysis	participated in the design of the study and performed the pet analysis	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5005244	27576896	ASH	2	carried out experimental work	carried out experimental work	Performed the experiments	Investigation	YES
5005244	27576896	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5005244	27576896	C-R	2	postdoctoral residence	postdoctoral residence	-	-	NO
5005244	27576896	CCR	2	carried out the experiments and wrote the manuscript	carried out the experiments and wrote the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5005244	27576896	FNRO	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5005244	27576896	GZ	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5005244	27576896	MEHL	2	conceived experiments and wrote the manuscript	conceived experiments and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5005244	27576896	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5005244	27576896	YGH	2	carried out experimental work	carried out experimental work	Performed the experiments	Investigation	YES
4414532	25923334	BKK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414532	25923334	BKK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414532	25923334	BKK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414532	25923334	DR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414532	25923334	DR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414532	25923334	DR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414532	25923334	DR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414532	25923334	GS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414532	25923334	GS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414532	25923334	GS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414532	25923334	RAK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414532	25923334	RAK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414532	25923334	RAK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1899227	17611624	AC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Contributed to the revision of the final submitted paper|Contributed to the revision of the final submitted paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1899227	17611624	AC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Contributed to the revision of the final submitted paper|Contributed to the revision of the final submitted paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1899227	17611624	AC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Contributed to the revision of the final submitted paper|Contributed to the revision of the final submitted paper	Contributed to the revision of the final submitted paper	Wrote the paper	Writing - Review & Editing	YES
1899227	17611624	AC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Contributed to the revision of the final submitted paper|Contributed to the revision of the final submitted paper	Contributed to the revision of the final submitted paper	Wrote the paper	Writing - Review & Editing	YES
1899227	17611624	AM	PLoS5	Contributed reagents/materials/analysis tools|Contributed to the revision of the final submitted paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1899227	17611624	AM	PLoS5	Contributed reagents/materials/analysis tools|Contributed to the revision of the final submitted paper	Contributed to the revision of the final submitted paper	Wrote the paper	Writing - Review & Editing	YES
1899227	17611624	AZ	PLoS5	Contributed reagents/materials/analysis tools|Contributed to the revision of the final submitted paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1899227	17611624	AZ	PLoS5	Contributed reagents/materials/analysis tools|Contributed to the revision of the final submitted paper	Contributed to the revision of the final submitted paper	Wrote the paper	Writing - Review & Editing	YES
1899227	17611624	GF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1899227	17611624	GF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1899227	17611624	GF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1899227	17611624	MP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Contributed to the revision of the final submitted paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1899227	17611624	MP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Contributed to the revision of the final submitted paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1899227	17611624	MP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Contributed to the revision of the final submitted paper	Contributed to the revision of the final submitted paper	Wrote the paper	Writing - Review & Editing	YES
1899227	17611624	MT	PLoS5	Contributed reagents/materials/analysis tools|Contributed to the revision of the final submitted paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1899227	17611624	MT	PLoS5	Contributed reagents/materials/analysis tools|Contributed to the revision of the final submitted paper	Contributed to the revision of the final submitted paper	Wrote the paper	Writing - Review & Editing	YES
1899227	17611624	PM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Contributed to the revision of the final submitted paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1899227	17611624	PM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Contributed to the revision of the final submitted paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1899227	17611624	PM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Contributed to the revision of the final submitted paper	Contributed to the revision of the final submitted paper	Wrote the paper	Writing - Review & Editing	YES
1899227	17611624	RM	PLoS5	Contributed reagents/materials/analysis tools|Contributed to the revision of the final submitted paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1899227	17611624	RM	PLoS5	Contributed reagents/materials/analysis tools|Contributed to the revision of the final submitted paper	Contributed to the revision of the final submitted paper	Wrote the paper	Writing - Review & Editing	YES
1899227	17611624	VP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed to the revision of the final submitted paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1899227	17611624	VP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed to the revision of the final submitted paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1899227	17611624	VP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed to the revision of the final submitted paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1899227	17611624	VP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed to the revision of the final submitted paper	Contributed to the revision of the final submitted paper	Wrote the paper	Writing - Review & Editing	YES
6102169	30128776	HD	2	participated in the data analysis	participated in the data analysis	Analyzed the data	Formal analysis	YES
6102169	30128776	MS	2	is the project leader and corresponding author	is the project leader and corresponding author	-	Supervision	YES
6102169	30128776	YT	2	participated in the data analysis	participated in the data analysis	Analyzed the data	Formal analysis	YES
5732353	29312376	C-LM	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5732353	29312376	L-QZ	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5732353	29312376	L-QZ	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5732353	29312376	LC	PLoS52	conceived of and designed the experiment|wrote the paper	conceived of and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5732353	29312376	LC	PLoS52	conceived of and designed the experiment|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5732353	29312376	S-YS	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5732353	29312376	WC	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5732353	29312376	Y-XX	PLoS52	conceived of and designed the experiment|performed the experiments|analyzed the data|wrote the paper	conceived of and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5732353	29312376	Y-XX	PLoS52	conceived of and designed the experiment|performed the experiments|analyzed the data|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5732353	29312376	Y-XX	PLoS52	conceived of and designed the experiment|performed the experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5732353	29312376	Y-XX	PLoS52	conceived of and designed the experiment|performed the experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5732353	29312376	Y-YZ	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5732353	29312376	Y-YZ	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5009059	27586595	HM	1	Planning and designing of study|Drafting	Planning and designing of study	Conceived and designed the experiments	Methodology	YES
5009059	27586595	HM	1	Planning and designing of study|Drafting	Drafting	Wrote the paper	Writing - Original Draft	YES
5009059	27586595	KK	1	Planning and designing of study|Drafting	Planning and designing of study	Conceived and designed the experiments	Methodology	YES
5009059	27586595	KK	1	Planning and designing of study|Drafting	Drafting	Wrote the paper	Writing - Original Draft	YES
5009059	27586595	MU	1	Planning and designing of study|Drafting	Planning and designing of study	Conceived and designed the experiments	Methodology	YES
5009059	27586595	MU	1	Planning and designing of study|Drafting	Drafting	Wrote the paper	Writing - Original Draft	YES
5009059	27586595	SA	1	Planning and designing of study|Experimentation and result analysis|Drafting	Planning and designing of study	Conceived and designed the experiments	Methodology	YES
5009059	27586595	SA	1	Planning and designing of study|Experimentation and result analysis|Drafting	Experimentation and result analysis	Performed the experiments	Investigation	YES
5009059	27586595	SA	1	Planning and designing of study|Experimentation and result analysis|Drafting	Drafting	Wrote the paper	Writing - Original Draft	YES
5009059	27586595	TI	1	Planning and designing of study|Experimentation and result analysis|Drafting	Planning and designing of study	Conceived and designed the experiments	Methodology	YES
5009059	27586595	TI	1	Planning and designing of study|Experimentation and result analysis|Drafting	Experimentation and result analysis	Performed the experiments	Investigation	YES
5009059	27586595	TI	1	Planning and designing of study|Experimentation and result analysis|Drafting	Drafting	Wrote the paper	Writing - Original Draft	YES
5605997	28927378	AT	1	Analysis and interpretation|Manuscript writing	Analysis and interpretation	Analyzed the data	Formal analysis	YES
5605997	28927378	AT	1	Analysis and interpretation|Manuscript writing	Manuscript writing	Wrote the paper	Writing - Original Draft	YES
5605997	28927378	CA	1	Experimental concept and design|Acquisition of data|Manuscript writing	Experimental concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5605997	28927378	CA	1	Experimental concept and design|Acquisition of data|Manuscript writing	Acquisition of data	Performed the experiments	Investigation	YES
5605997	28927378	CA	1	Experimental concept and design|Acquisition of data|Manuscript writing	Manuscript writing	Wrote the paper	Writing - Original Draft	YES
5605997	28927378	DM	1	Experimental concept and design|Acquisition of data|Analysis and interpretation|Manuscript writing	Experimental concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5605997	28927378	DM	1	Experimental concept and design|Acquisition of data|Analysis and interpretation|Manuscript writing	Acquisition of data	Performed the experiments	Investigation	YES
5605997	28927378	DM	1	Experimental concept and design|Acquisition of data|Analysis and interpretation|Manuscript writing	Analysis and interpretation	Analyzed the data	Formal analysis	YES
5605997	28927378	DM	1	Experimental concept and design|Acquisition of data|Analysis and interpretation|Manuscript writing	Manuscript writing	Wrote the paper	Writing - Original Draft	YES
5605997	28927378	DQ	1	Experimental concept and design|Analysis and interpretation|Manuscript writing	Experimental concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5605997	28927378	DQ	1	Experimental concept and design|Analysis and interpretation|Manuscript writing	Analysis and interpretation	Analyzed the data	Formal analysis	YES
5605997	28927378	DQ	1	Experimental concept and design|Analysis and interpretation|Manuscript writing	Manuscript writing	Wrote the paper	Writing - Original Draft	YES
5605997	28927378	HV	1	Analysis and interpretation	Analysis and interpretation	Analyzed the data	Formal analysis	YES
5605997	28927378	JJ	1	Analysis and interpretation|Manuscript writing	Analysis and interpretation	Analyzed the data	Formal analysis	YES
5605997	28927378	JJ	1	Analysis and interpretation|Manuscript writing	Manuscript writing	Wrote the paper	Writing - Original Draft	YES
5605997	28927378	MV	1	Analysis and interpretation	Analysis and interpretation	Analyzed the data	Formal analysis	YES
5605997	28927378	PB	1	Acquisition of data	Acquisition of data	Performed the experiments	Investigation	YES
5605997	28927378	RK	1	Experimental concept and design|Acquisition of data	Experimental concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5605997	28927378	RK	1	Experimental concept and design|Acquisition of data	Acquisition of data	Performed the experiments	Investigation	YES
5605997	28927378	RS	1	Experimental concept and design|Acquisition of data|Manuscript writing	Experimental concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5605997	28927378	RS	1	Experimental concept and design|Acquisition of data|Manuscript writing	Acquisition of data	Performed the experiments	Investigation	YES
5605997	28927378	RS	1	Experimental concept and design|Acquisition of data|Manuscript writing	Manuscript writing	Wrote the paper	Writing - Original Draft	YES
5605997	28927378	YH	1	Analysis and interpretation	Analysis and interpretation	Analyzed the data	Formal analysis	YES
5605997	28927378	YL	1	Analysis and interpretation	Analysis and interpretation	Analyzed the data	Formal analysis	YES
1899228	17611625	FT	1	Conceived the project and wrote the paper	Conceived the project and wrote the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
1899228	17611625	SPB	1	Conceived the project and wrote the paper|Performed the model development and analysis	Conceived the project and wrote the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
1899228	17611625	SPB	1	Conceived the project and wrote the paper|Performed the model development and analysis	Performed the model development and analysis	Performed the experiments	Investigation|Methodology	YES
4414533	25923693	AH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414533	25923693	AH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414533	25923693	AH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414533	25923693	CW	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414533	25923693	CW	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414533	25923693	CW	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414533	25923693	CW	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414533	25923693	JW	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414533	25923693	JW	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414533	25923693	JW	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414533	25923693	JW	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414533	25923693	QZ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4414533	25923693	QZ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4414533	25923693	QZ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414533	25923693	YY	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414533	25923693	YY	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414533	25923693	YY	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414533	25923693	YZ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414533	25923693	YZ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414533	25923693	YZ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414533	25923693	YZ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414533	25923693	ZD	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4414533	25923693	ZD	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4414533	25923693	ZD	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4609416	26504844	Chanjiao Zheng	PLoS52	were responsible for literature searching and data extraction	were responsible for literature searching and data extraction	Analyzed the data	Data curation|Formal analysis	YES
4609416	26504844	Huanyu Shen	PLoS52	were responsible for literature searching and data extraction	were responsible for literature searching and data extraction	Analyzed the data	Data curation|Formal analysis	YES
4609416	26504844	Qun Liu	PLoS52	conceived and designed the research|wrote the paper	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
4609416	26504844	Qun Liu	PLoS52	conceived and designed the research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4609416	26504844	Yixiong Lei	PLoS52	revised the paper	revised the paper	Wrote the paper	Writing - Review & Editing	YES
4609416	26504844	Zhiheng Zhou	PLoS52	conceived and designed the research|was responsible for the quality assessment of studies|revised the paper	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
4609416	26504844	Zhiheng Zhou	PLoS52	conceived and designed the research|was responsible for the quality assessment of studies|revised the paper	was responsible for the quality assessment of studies	-	Validation	YES
4609416	26504844	Zhiheng Zhou	PLoS52	conceived and designed the research|was responsible for the quality assessment of studies|revised the paper	revised the paper	Wrote the paper	Writing - Review & Editing	YES
5732357	29312364	AF	2	also put the reference list together	also put the reference list together	-	-	NO
5732357	29312364	All authors	2	have read and approved the submitted manuscript	have read and approved the submitted manuscript	-	-	NO
5732357	29312364	VN	2	conceptualized figure 1	conceptualized figure 1	Conceived and designed the experiments	Conceptualization|Visualization	YES
4176132	24176020	CMK	2	assisted with the conduction of the clinical trial	assisted with the conduction of the clinical trial	Performed the experiments	Investigation	YES
4176132	24176020	EA	2	assisted with the data analysis	assisted with the data analysis	Analyzed the data	Formal analysis	YES
4176132	24176020	JFT	2	assisted with the data analysis	assisted with the data analysis	Analyzed the data	Formal analysis	YES
4176132	24176020	KAV	2	assisted with the design of the experiment, and wrote the manuscript	assisted with the design of the experiment, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
4176132	24176020	KKH	2	assisted with the data analysis	assisted with the data analysis	Analyzed the data	Formal analysis	YES
4176132	24176020	MCK	2	assisted with the conduction of the clinical trial	assisted with the conduction of the clinical trial	Performed the experiments	Investigation	YES
4176132	24176020	SB	2	designed the experiment, conducted the clinical trial, analyzed the data, and wrote the manuscript	designed the experiment, conducted the clinical trial, analyzed the data, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4176132	24176020	YC	2	assisted with the data analysis	assisted with the data analysis	Analyzed the data	Formal analysis	YES
5010549	27590888	CS	1	Analysis	Analysis	-	-	NO
5010549	27590888	FL	1	Planning and designing of study|Drafting	Planning and designing of study	Conceived and designed the experiments	Methodology	YES
5010549	27590888	FL	1	Planning and designing of study|Drafting	Drafting	Wrote the paper	Writing - Original Draft	YES
5010549	27590888	RZ	1	Experimentation	Experimentation	Performed the experiments	Investigation	YES
5010549	27590888	YW	1	Experimentation|Analysis	Experimentation	Performed the experiments	Investigation	YES
5010549	27590888	YW	1	Experimentation|Analysis	Analysis	-	-	NO
5010549	27590888	YZ	1	Planning and designing of study|Experimentation|Analysis|Drafting	Planning and designing of study	Conceived and designed the experiments	Methodology	YES
5010549	27590888	YZ	1	Planning and designing of study|Experimentation|Analysis|Drafting	Experimentation	Performed the experiments	Investigation	YES
5010549	27590888	YZ	1	Planning and designing of study|Experimentation|Analysis|Drafting	Analysis	-	-	NO
5010549	27590888	YZ	1	Planning and designing of study|Experimentation|Analysis|Drafting	Drafting	Wrote the paper	Writing - Original Draft	YES
5010549	27590888	ZS	1	Drafting	Drafting	Wrote the paper	Writing - Original Draft	YES
4414534	25923527	KR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414534	25923527	KR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414534	25923527	KR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414534	25923527	KR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414534	25923527	KR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414534	25923527	TA	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414534	25923527	TA	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414534	25923527	TA	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6104414	30136081	EEV	2	contributed to the preparation of the scanning procedure and manuscript correction	contributed to the preparation of the scanning procedure and manuscript correction	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
6104414	30136081	JB	2	contributed to the design of the study, manuscript correction, and expert interpretation of the results	contributed to the design of the study, manuscript correction, and expert interpretation of the results	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
6104414	30136081	KMdB	2	contributed to the preparation of scanning procedure and expert interpretation of the results	contributed to the preparation of scanning procedure and expert interpretation of the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6104414	30136081	MKS	2	contributed to the preparation of the scanning procedure, scanning patients, and manuscript correction	contributed to the preparation of the scanning procedure, scanning patients, and manuscript correction	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
6104414	30136081	SMA	2	contributed to the analysis and interpretation of the data and writing of the manuscript	contributed to the analysis and interpretation of the data and writing of the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
6104414	30136081	TCdW	2	contributed to the design of the study, expert interpretation of the results, and manuscript correction	contributed to the design of the study, expert interpretation of the results, and manuscript correction	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
1899229	17622349	EB	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1899229	17622349	EB	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1899229	17622349	EP	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1899229	17622349	EP	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1899229	17622349	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1899229	17622349	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1899229	17622349	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1899229	17622349	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1899229	17622349	MS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1899229	17622349	MS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1899229	17622349	TP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1899229	17622349	TP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1899229	17622349	TP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1899229	17622349	TP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5606014	28931375	GG	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5606014	28931375	J-FH	PLoS52	analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5606014	28931375	J-FH	PLoS52	analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5606014	28931375	KSS	PLoS52	performed protein modeling|analyzed the data|wrote the paper	performed protein modeling	Performed the experiments	Investigation|Methodology	YES
5606014	28931375	KSS	PLoS52	performed protein modeling|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5606014	28931375	KSS	PLoS52	performed protein modeling|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5606014	28931375	LM-P	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5606014	28931375	MB	PLoS52	contributed to the rt-qpcr and bioinformatics analyses	contributed to the rt-qpcr and bioinformatics analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4176133	24215679	AAM	2	was responsible for the study design, the execution of the measurements, the statistical analysis and the writing of the manuscript	was responsible for the study design, the execution of the measurements, the statistical analysis and the writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4176133	24215679	JRH	2	participated in the study design and in the writing of the manuscript	participated in the study design and in the writing of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4176133	24215679	JRS	2	participated in the study design and in the writing of the manuscript	participated in the study design and in the writing of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4176133	24215679	JS	2	participated in the study design, execution of the measurements, the statistical analysis and the writing of the manuscript	participated in the study design, execution of the measurements, the statistical analysis and the writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4176133	24215679	PH	2	participated in the study design, execution of the measurements, the statistical analysis and the writing of the manuscript	participated in the study design, execution of the measurements, the statistical analysis and the writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5016484	27620730	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5016484	27620730	BW	2	performed research	performed research	Performed the experiments	Investigation	YES
5016484	27620730	CCCRC	2	designed research and wrote the paper|analyzed data	designed research and wrote the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5016484	27620730	CCCRC	2	designed research and wrote the paper|analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5016484	27620730	HJH	2	designed research and wrote the paper|analyzed data	designed research and wrote the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5016484	27620730	HJH	2	designed research and wrote the paper|analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5016484	27620730	LYW	2	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5016484	27620730	MAF	2	performed research	performed research	Performed the experiments	Investigation	YES
5016484	27620730	SK	2	performed research	performed research	Performed the experiments	Investigation	YES
5732361	29312362	BA	PLoS52	designed the experiments|wrote the paper	designed the experiments	Conceived and designed the experiments	Methodology	YES
5732361	29312362	BA	PLoS52	designed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5732361	29312362	BM	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5732361	29312362	CT	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5732361	29312362	FI	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5732361	29312362	MG	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5732361	29312362	RG	PLoS52	designed the experiments|performed the experiments|analyzed the data|wrote the paper	designed the experiments	Conceived and designed the experiments	Methodology	YES
5732361	29312362	RG	PLoS52	designed the experiments|performed the experiments|analyzed the data|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5732361	29312362	RG	PLoS52	designed the experiments|performed the experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5732361	29312362	RG	PLoS52	designed the experiments|performed the experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5732361	29312362	SA	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5732361	29312362	SL	PLoS52	designed the experiments|wrote the paper	designed the experiments	Conceived and designed the experiments	Methodology	YES
5732361	29312362	SL	PLoS52	designed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5732361	29312362	SY	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5732361	29312362	TM	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5732361	29312362	WZ	PLoS52	designed the experiments|wrote the paper	designed the experiments	Conceived and designed the experiments	Methodology	YES
5732361	29312362	WZ	PLoS52	designed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414535	25923915	DMG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414535	25923915	DMG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414535	25923915	DMG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414535	25923915	DMG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414535	25923915	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414535	25923915	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414535	25923915	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414535	25923915	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414535	25923915	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6104464	30136163	AB	2	were involved in clinical care, surgical and histopathological data collection and and manuscript preparation	were involved in clinical care, surgical and histopathological data collection and and manuscript preparation	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6104464	30136163	CC	2	was involved in study design, implementation, analysis	was involved in study design, implementation, analysis	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6104464	30136163	CM	2	contributed to prepare and revise the manuscript enhancing its content and its usefulness in clinical practice	contributed to prepare and revise the manuscript enhancing its content and its usefulness in clinical practice	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6104464	30136163	CT	2	interpretation, image analysis and manuscript preparation	interpretation, image analysis and manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Visualization|Writing - Original Draft	YES
6104464	30136163	DV	2	were involved in clinical care, surgical and histopathological data collection and and manuscript preparation	were involved in clinical care, surgical and histopathological data collection and and manuscript preparation	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6104464	30136163	ED	2	was involved in study design, implementation, analysis, machine-learning analysis and manuscript preparation	was involved in study design, implementation, analysis, machine-learning analysis and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
6104464	30136163	PET	2	analysis and segmentation and manuscript preparation	analysis and segmentation and manuscript preparation	Wrote the paper	Writing - Original Draft	YES
6104464	30136163	RF	2	were involved in clinical care, surgical and histopathological data collection and and manuscript preparation	were involved in clinical care, surgical and histopathological data collection and and manuscript preparation	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5609056	28934931	AK	1	Conceptualised idea for research|Postgraduate supervisor of the lead author	Conceptualised idea for research	Conceived and designed the experiments	Conceptualization	YES
5609056	28934931	AK	1	Conceptualised idea for research|Postgraduate supervisor of the lead author	Postgraduate supervisor of the lead author	-	Supervision	YES
5609056	28934931	DLD	1	Responsible for data collection/analysis/design|Editorial input|Postgraduate supervisor of the lead author|Project leader/budget owner	Responsible for data collection/analysis/design	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5609056	28934931	DLD	1	Responsible for data collection/analysis/design|Editorial input|Postgraduate supervisor of the lead author|Project leader/budget owner	Editorial input	-	-	NO
5609056	28934931	DLD	1	Responsible for data collection/analysis/design|Editorial input|Postgraduate supervisor of the lead author|Project leader/budget owner	Postgraduate supervisor of the lead author	-	Supervision	YES
5609056	28934931	DLD	1	Responsible for data collection/analysis/design|Editorial input|Postgraduate supervisor of the lead author|Project leader/budget owner	Project leader/budget owner	-	Supervision	YES
5609056	28934931	JPG	1	Responsible for data collection/analysis/design|Editorial input|Postgraduate supervisor of the lead author	Responsible for data collection/analysis/design	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5609056	28934931	JPG	1	Responsible for data collection/analysis/design|Editorial input|Postgraduate supervisor of the lead author	Editorial input	-	-	NO
5609056	28934931	JPG	1	Responsible for data collection/analysis/design|Editorial input|Postgraduate supervisor of the lead author	Postgraduate supervisor of the lead author	-	Supervision	YES
5609056	28934931	MDP	1	Responsible for data collection/analysis/design|Editorial input	Responsible for data collection/analysis/design	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5609056	28934931	MDP	1	Responsible for data collection/analysis/design|Editorial input	Editorial input	-	-	NO
5609056	28934931	RJ	1	Editorial input	Editorial input	-	-	NO
5609056	28934931	ZDT	1	Responsible for data collection/analysis/design|Lead author writing up of article|Editorial input	Responsible for data collection/analysis/design	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5609056	28934931	ZDT	1	Responsible for data collection/analysis/design|Lead author writing up of article|Editorial input	Lead author writing up of article	Wrote the paper	Writing - Original Draft	YES
5609056	28934931	ZDT	1	Responsible for data collection/analysis/design|Lead author writing up of article|Editorial input	Editorial input	-	-	NO
1899230	17611618	DL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1899230	17611618	MG	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1899230	17611618	MG	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1899230	17611618	RM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1899230	17611618	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1899230	17611618	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1899230	17611618	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1899230	17611618	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1899230	17611618	VF	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
6104465	30136051	AS	2	was involved in the in vitro and in vivo evaluation, performed the data evaluation and interpretation, and revised the manuscript	was involved in the in vitro and in vivo evaluation, performed the data evaluation and interpretation, and revised the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
6104465	30136051	HJW	2	initiated the development and evaluation of the lipophilic psma inhibitors and participated in the data interpretation and in writing the manuscript and revising the final manuscript	initiated the development and evaluation of the lipophilic psma inhibitors and participated in the data interpretation and in writing the manuscript and revising the final manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
6104465	30136051	MScho	2	participated in the data interpretation and in revising the manuscript	participated in the data interpretation and in revising the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
6104465	30136051	MSchw	2	supported the preclinical evaluation of the psma inhibitors and in revising the final manuscript	supported the preclinical evaluation of the psma inhibitors and in revising the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6104465	30136051	MW	2	carried out the design and synthesis of the psma ligands, performed the preclinical in vitro and in vivo evaluation, and drafted the manuscript	carried out the design and synthesis of the psma ligands, performed the preclinical in vitro and in vivo evaluation, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6104465	30136051	SR	2	were involved in the in vitro evaluation and revised the final manuscript	were involved in the in vitro evaluation and revised the final manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
6104465	30136051	TG	2	were involved in the in vitro evaluation and revised the final manuscript	were involved in the in vitro evaluation and revised the final manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4190921	25342934	HH	PLoS52	conceived and designed the study|performed the experiments|performed the experiments|carried out immunoassay|carried out immunoassay|analyzed the data and wrote the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4190921	25342934	HH	PLoS52	conceived and designed the study|performed the experiments|performed the experiments|carried out immunoassay|carried out immunoassay|analyzed the data and wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
4190921	25342934	HH	PLoS52	conceived and designed the study|performed the experiments|performed the experiments|carried out immunoassay|carried out immunoassay|analyzed the data and wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
4190921	25342934	HH	PLoS52	conceived and designed the study|performed the experiments|performed the experiments|carried out immunoassay|carried out immunoassay|analyzed the data and wrote the manuscript	carried out immunoassay	Performed the experiments	Investigation	YES
4190921	25342934	HH	PLoS52	conceived and designed the study|performed the experiments|performed the experiments|carried out immunoassay|carried out immunoassay|analyzed the data and wrote the manuscript	carried out immunoassay	Performed the experiments	Investigation	YES
4190921	25342934	HH	PLoS52	conceived and designed the study|performed the experiments|performed the experiments|carried out immunoassay|carried out immunoassay|analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4190921	25342934	KS	PLoS52	conceived and designed the study|performed blood sampling	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4190921	25342934	KS	PLoS52	conceived and designed the study|performed blood sampling	performed blood sampling	Performed the experiments	Investigation	YES
4190921	25342934	MH	PLoS52	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4190921	25342934	TI	PLoS52	conceived and designed the study|performed the experiments|carried out immunoassay	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4190921	25342934	TI	PLoS52	conceived and designed the study|performed the experiments|carried out immunoassay	performed the experiments	Performed the experiments	Investigation	YES
4190921	25342934	TI	PLoS52	conceived and designed the study|performed the experiments|carried out immunoassay	carried out immunoassay	Performed the experiments	Investigation	YES
5016490	27620731	AS	2	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5016490	27620731	All authors	2	commented the manuscript|read and approved the final manuscript	commented the manuscript	-	-	NO
5016490	27620731	All authors	2	commented the manuscript|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5016490	27620731	CM	2	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5016490	27620731	JB	2	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5016490	27620731	JZ	2	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5016490	27620731	RV	2	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5016490	27620731	WG	2	designed the study and conducted experiments|analyzed data|wrote the manuscript	designed the study and conducted experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5016490	27620731	WG	2	designed the study and conducted experiments|analyzed data|wrote the manuscript	analyzed data	Analyzed the data	Formal analysis	YES
5016490	27620731	WG	2	designed the study and conducted experiments|analyzed data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4414536	25923691	AS	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414536	25923691	EB	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414536	25923691	EB	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414536	25923691	MM	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414536	25923691	MM	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4609430	26504849	A. Groza	PLoS52	conceived the study|wrote the paper	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4609430	26504849	A. Groza	PLoS52	conceived the study|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4609430	26504849	All authors	PLoS52	contributed to the interpretation of results and discussion and read, corrected, and approved the final paper	contributed to the interpretation of results and discussion and read, corrected, and approved the final paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4609430	26504849	C. L. Popa	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4609430	26504849	C. S. Ciobanu	PLoS52	performed the synthesis of the powders	performed the synthesis of the powders	Performed the experiments	Investigation	YES
4609430	26504849	D. Predoi	PLoS52	conceived the study|directed the study|wrote the paper	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4609430	26504849	D. Predoi	PLoS52	conceived the study|directed the study|wrote the paper	directed the study	-	Supervision	YES
4609430	26504849	D. Predoi	PLoS52	conceived the study|directed the study|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4609430	26504849	HAp	PLoS52	thin films	thin films	-	-	NO
4609430	26504849	M. Ganciu	PLoS52	performed the depositions of the pdms thin films	performed the depositions of the pdms thin films	Performed the experiments	Investigation	YES
4190923	25302053	AS	2	prepared the manuscript|performed statistical analysis	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
4190923	25302053	AS	2	prepared the manuscript|performed statistical analysis	performed statistical analysis	Analyzed the data	Formal analysis	YES
4190923	25302053	CF	2	provided administrative oversight	provided administrative oversight	-	Supervision	YES
4190923	25302053	CW	2	prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
4190923	25302053	JO	2	prepared the manuscript|performed data collection	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
4190923	25302053	JO	2	prepared the manuscript|performed data collection	performed data collection	Performed the experiments	Investigation	YES
4190923	25302053	LM	2	assisted with manuscript editing and revisions	assisted with manuscript editing and revisions	Wrote the paper	Writing - Review & Editing	YES
4190923	25302053	SH	2	prepared the manuscript|performed data collection|performed statistical analysis	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
4190923	25302053	SH	2	prepared the manuscript|performed data collection|performed statistical analysis	performed data collection	Performed the experiments	Investigation	YES
4190923	25302053	SH	2	prepared the manuscript|performed data collection|performed statistical analysis	performed statistical analysis	Analyzed the data	Formal analysis	YES
4190923	25302053	SU	2	performed data collection	performed data collection	Performed the experiments	Investigation	YES
6113196	30155674	AS	PLoS52	conducted the experiments	conducted the experiments	Performed the experiments	Investigation	YES
6113196	30155674	CB	PLoS52	designed the experiments|conducted the experiments|analyzed the data|wrote the paper	designed the experiments	Conceived and designed the experiments	Methodology	YES
6113196	30155674	CB	PLoS52	designed the experiments|conducted the experiments|analyzed the data|wrote the paper	conducted the experiments	Performed the experiments	Investigation	YES
6113196	30155674	CB	PLoS52	designed the experiments|conducted the experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
6113196	30155674	CB	PLoS52	designed the experiments|conducted the experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6113196	30155674	JAK	PLoS52	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
6113196	30155674	JFP	PLoS52	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
6113196	30155674	JH	PLoS52	designed the experiments|conducted the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
6113196	30155674	JH	PLoS52	designed the experiments|conducted the experiments	conducted the experiments	Performed the experiments	Investigation	YES
6113196	30155674	JL	PLoS52	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
6113196	30155674	KG	PLoS52	conducted the experiments	conducted the experiments	Performed the experiments	Investigation	YES
6113196	30155674	NVKP	PLoS52	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
6113196	30155674	TR	PLoS52	designed the experiments|analyzed the data|wrote the paper	designed the experiments	Conceived and designed the experiments	Methodology	YES
6113196	30155674	TR	PLoS52	designed the experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
6113196	30155674	TR	PLoS52	designed the experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
1899231	17611627	AV	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1899231	17611627	AV	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1899231	17611627	AV	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1899231	17611627	BA	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1899231	17611627	IM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1899231	17611627	JP	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1899231	17611627	JR	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1899231	17611627	JR	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1899231	17611627	NL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1899231	17611627	NL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1899231	17611627	NL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1899231	17611627	NL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1899231	17611627	PC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1899231	17611627	SC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5732362	29312372	AZ	PLoS52	were responsible for dna markers analysis and linkage analysis	were responsible for dna markers analysis and linkage analysis	-	-	NO
5732362	29312372	CZ	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5732362	29312372	DL	PLoS52	were responsible for dna markers analysis and linkage analysis	were responsible for dna markers analysis and linkage analysis	-	-	NO
5732362	29312372	XZ	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5732362	29312372	YQ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5732362	29312372	YR	PLoS52	performed the experiments|contributed to genetic mapping and qtl analysis|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5732362	29312372	YR	PLoS52	performed the experiments|contributed to genetic mapping and qtl analysis|wrote the paper	contributed to genetic mapping and qtl analysis	Performed the experiments	Investigation	YES
5732362	29312372	YR	PLoS52	performed the experiments|contributed to genetic mapping and qtl analysis|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5732362	29312372	YT	PLoS52	conceived and designed the experiments|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5732362	29312372	YT	PLoS52	conceived and designed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5732362	29312372	YX	PLoS52	contributed to genetic mapping and qtl analysis	contributed to genetic mapping and qtl analysis	Performed the experiments	Investigation	YES
5609061	28934930	AM	2	developed all the algorithms of the xcavator tool and performed all the comparison analyses	developed all the algorithms of the xcavator tool and performed all the comparison analyses	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Software	YES
5609061	28934930	All the authors	2	supervised the work and contributed to write the manuscript	supervised the work and contributed to write the manuscript	Wrote the paper	Supervision|Writing - Original Draft	YES
5609061	28934930	CS	2	performed population data analysis	performed population data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5609061	28934930	TP	2	interpreted the results	interpreted the results	Analyzed the data	Formal analysis	YES
4414537	25923690	CH	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4414537	25923690	HC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Conception and design of the work and acquisition of data|Meta-analysis|Drafted the article or revised it critically for important intellectual content|Final approval of the version to be published|Agreed to be accountable for all aspects of the work	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414537	25923690	HC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Conception and design of the work and acquisition of data|Meta-analysis|Drafted the article or revised it critically for important intellectual content|Final approval of the version to be published|Agreed to be accountable for all aspects of the work	Performed the experiments	Performed the experiments	Investigation	YES
4414537	25923690	HC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Conception and design of the work and acquisition of data|Meta-analysis|Drafted the article or revised it critically for important intellectual content|Final approval of the version to be published|Agreed to be accountable for all aspects of the work	Analyzed the data	Analyzed the data	Formal analysis	YES
4414537	25923690	HC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Conception and design of the work and acquisition of data|Meta-analysis|Drafted the article or revised it critically for important intellectual content|Final approval of the version to be published|Agreed to be accountable for all aspects of the work	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414537	25923690	HC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Conception and design of the work and acquisition of data|Meta-analysis|Drafted the article or revised it critically for important intellectual content|Final approval of the version to be published|Agreed to be accountable for all aspects of the work	Conception and design of the work and acquisition of data	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
4414537	25923690	HC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Conception and design of the work and acquisition of data|Meta-analysis|Drafted the article or revised it critically for important intellectual content|Final approval of the version to be published|Agreed to be accountable for all aspects of the work	Meta-analysis	Analyzed the data	Formal analysis	YES
4414537	25923690	HC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Conception and design of the work and acquisition of data|Meta-analysis|Drafted the article or revised it critically for important intellectual content|Final approval of the version to be published|Agreed to be accountable for all aspects of the work	Drafted the article or revised it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4414537	25923690	HC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Conception and design of the work and acquisition of data|Meta-analysis|Drafted the article or revised it critically for important intellectual content|Final approval of the version to be published|Agreed to be accountable for all aspects of the work	Final approval of the version to be published	-	-	NO
4414537	25923690	HC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Conception and design of the work and acquisition of data|Meta-analysis|Drafted the article or revised it critically for important intellectual content|Final approval of the version to be published|Agreed to be accountable for all aspects of the work	Agreed to be accountable for all aspects of the work	-	-	NO
4414537	25923690	LG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Conception and design of the work and acquisition of data|Meta-analysis|Drafted the article or revised it critically for important intellectual content|Final approval of the version to be published|Agreed to be accountable for all aspects of the work	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414537	25923690	LG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Conception and design of the work and acquisition of data|Meta-analysis|Drafted the article or revised it critically for important intellectual content|Final approval of the version to be published|Agreed to be accountable for all aspects of the work	Analyzed the data	Analyzed the data	Formal analysis	YES
4414537	25923690	LG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Conception and design of the work and acquisition of data|Meta-analysis|Drafted the article or revised it critically for important intellectual content|Final approval of the version to be published|Agreed to be accountable for all aspects of the work	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414537	25923690	LG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Conception and design of the work and acquisition of data|Meta-analysis|Drafted the article or revised it critically for important intellectual content|Final approval of the version to be published|Agreed to be accountable for all aspects of the work	Conception and design of the work and acquisition of data	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
4414537	25923690	LG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Conception and design of the work and acquisition of data|Meta-analysis|Drafted the article or revised it critically for important intellectual content|Final approval of the version to be published|Agreed to be accountable for all aspects of the work	Meta-analysis	Analyzed the data	Formal analysis	YES
4414537	25923690	LG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Conception and design of the work and acquisition of data|Meta-analysis|Drafted the article or revised it critically for important intellectual content|Final approval of the version to be published|Agreed to be accountable for all aspects of the work	Drafted the article or revised it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4414537	25923690	LG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Conception and design of the work and acquisition of data|Meta-analysis|Drafted the article or revised it critically for important intellectual content|Final approval of the version to be published|Agreed to be accountable for all aspects of the work	Final approval of the version to be published	-	-	NO
4414537	25923690	LG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Conception and design of the work and acquisition of data|Meta-analysis|Drafted the article or revised it critically for important intellectual content|Final approval of the version to be published|Agreed to be accountable for all aspects of the work	Agreed to be accountable for all aspects of the work	-	-	NO
4414537	25923690	ML	PLoS5	Wrote the paper|Conception and design of the work and acquisition of data|Drafted the article or revised it critically for important intellectual content|Final approval of the version to be published|Agreed to be accountable for all aspects of the work	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414537	25923690	ML	PLoS5	Wrote the paper|Conception and design of the work and acquisition of data|Drafted the article or revised it critically for important intellectual content|Final approval of the version to be published|Agreed to be accountable for all aspects of the work	Conception and design of the work and acquisition of data	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
4414537	25923690	ML	PLoS5	Wrote the paper|Conception and design of the work and acquisition of data|Drafted the article or revised it critically for important intellectual content|Final approval of the version to be published|Agreed to be accountable for all aspects of the work	Drafted the article or revised it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4414537	25923690	ML	PLoS5	Wrote the paper|Conception and design of the work and acquisition of data|Drafted the article or revised it critically for important intellectual content|Final approval of the version to be published|Agreed to be accountable for all aspects of the work	Final approval of the version to be published	-	-	NO
4414537	25923690	ML	PLoS5	Wrote the paper|Conception and design of the work and acquisition of data|Drafted the article or revised it critically for important intellectual content|Final approval of the version to be published|Agreed to be accountable for all aspects of the work	Agreed to be accountable for all aspects of the work	-	-	NO
4414537	25923690	QS	PLoS5	Analyzed the data|Wrote the paper|Final approval of the version to be published|Agreed to be accountable for all aspects of the work	Analyzed the data	Analyzed the data	Formal analysis	YES
4414537	25923690	QS	PLoS5	Analyzed the data|Wrote the paper|Final approval of the version to be published|Agreed to be accountable for all aspects of the work	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414537	25923690	QS	PLoS5	Analyzed the data|Wrote the paper|Final approval of the version to be published|Agreed to be accountable for all aspects of the work	Final approval of the version to be published	-	-	NO
4414537	25923690	QS	PLoS5	Analyzed the data|Wrote the paper|Final approval of the version to be published|Agreed to be accountable for all aspects of the work	Agreed to be accountable for all aspects of the work	-	-	NO
4190925	25302055	BEA	2	contributed to the conception and design of the study and revising the manuscript for intellectual content	contributed to the conception and design of the study and revising the manuscript for intellectual content	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
4190925	25302055	JMK	2	contributed to the acquisition of data, analysis and interpretation of data, drafting of the manuscript, and revising the manuscript for intellectual content	contributed to the acquisition of data, analysis and interpretation of data, drafting of the manuscript, and revising the manuscript for intellectual content	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
4190925	25302055	MPB	2	contributed to the analysis and interpretation of the data and revising the manuscript for intellectual content	contributed to the analysis and interpretation of the data and revising the manuscript for intellectual content	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
6115319	30159614	DH	4	The manuscript was drafted by	The manuscript was drafted by	Wrote the paper	Writing - Original Draft	YES
6115319	30159614	LW	4	The manuscript was drafted by	The manuscript was drafted by	Wrote the paper	Writing - Original Draft	YES
6115319	30159614	MS	4	was discussed and critically revised by	was discussed and critically revised by	Wrote the paper	Writing - Review & Editing	YES
6115319	30159614	MV	4	was discussed and critically revised by	was discussed and critically revised by	Wrote the paper	Writing - Review & Editing	YES
5609062	28934927	CZ	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5609062	28934927	WN	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5609062	28934927	YG	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5609062	28934927	YW	2	conceived and initiated the work	conceived and initiated the work	Conceived and designed the experiments	Conceptualization	YES
5609062	28934927	YX	2	conceived and initiated the work	conceived and initiated the work	Conceived and designed the experiments	Conceptualization	YES
5609062	28934927	ZL	2	designed the experiments|carried out the experiments|analyzed the data and wrote the paper	designed the experiments	Conceived and designed the experiments	Methodology	YES
5609062	28934927	ZL	2	designed the experiments|carried out the experiments|analyzed the data and wrote the paper	carried out the experiments	Performed the experiments	Investigation	YES
5609062	28934927	ZL	2	designed the experiments|carried out the experiments|analyzed the data and wrote the paper	analyzed the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
1899232	17622340	ES	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1899232	17622340	ES	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1899232	17622340	ES	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1899232	17622340	ES	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1899232	17622340	IZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1899232	17622340	IZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1899232	17622340	IZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1899232	17622340	IZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4190927	25302054	JAF	4	Revision of the manuscript by	Revision of the manuscript by	Wrote the paper	Writing - Review & Editing	YES
4190927	25302054	JSVV	4	analysis and interpretation of data by	analysis and interpretation of data by	Analyzed the data	Formal analysis	YES
4190927	25302054	JVVS	4	Conception and design of the study by	Conception and design of the study by	Conceived and designed the experiments	Conceptualization|Methodology	YES
4190927	25302054	MPTCM	4	Conception and design of the study by|Approval of the final version of the manuscript by	Conception and design of the study by	Conceived and designed the experiments	Conceptualization|Methodology	YES
4190927	25302054	MPTCM	4	Conception and design of the study by|Approval of the final version of the manuscript by	Approval of the final version of the manuscript by	-	-	NO
4190927	25302054	PCBL	4	analysis and interpretation of data by	analysis and interpretation of data by	Analyzed the data	Formal analysis	YES
4414538	25923778	JL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414538	25923778	JL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414538	25923778	JL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414538	25923778	WZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414538	25923778	WZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414538	25923778	WZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5732921	29312370	All authors	2	contributed to writing of the manuscript	contributed to writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5016491	27620732	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5016491	27620732	DZ	2	have conceived and designed experiments|have contributed reagents/analysis tools|helped with the has written the research paper with	have conceived and designed experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5016491	27620732	DZ	2	have conceived and designed experiments|have contributed reagents/analysis tools|helped with the has written the research paper with	have contributed reagents/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5016491	27620732	DZ	2	have conceived and designed experiments|have contributed reagents/analysis tools|helped with the has written the research paper with	helped with the has written the research paper with	Wrote the paper	Writing - Original Draft	YES
5016491	27620732	FY	2	have contributed reagents/analysis tools	have contributed reagents/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5016491	27620732	JX	2	have conceived and designed experiments|have performed the experiments|have analyzed the data|has written the research paper with	have conceived and designed experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5016491	27620732	JX	2	have conceived and designed experiments|have performed the experiments|have analyzed the data|has written the research paper with	have performed the experiments	Performed the experiments	Investigation	YES
5016491	27620732	JX	2	have conceived and designed experiments|have performed the experiments|have analyzed the data|has written the research paper with	have analyzed the data	Analyzed the data	Formal analysis	YES
5016491	27620732	JX	2	have conceived and designed experiments|have performed the experiments|have analyzed the data|has written the research paper with	has written the research paper with	Wrote the paper	Writing - Original Draft	YES
5016491	27620732	LL	2	have contributed reagents/analysis tools	have contributed reagents/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5016491	27620732	Ningbo City	2	the kc wong magna fund of ningbo university	the kc wong magna fund of ningbo university	-	-	NO
5016491	27620732	PQ	2	have performed the experiments|have analyzed the data	have performed the experiments	Performed the experiments	Investigation	YES
5016491	27620732	PQ	2	have performed the experiments|have analyzed the data	have analyzed the data	Analyzed the data	Formal analysis	YES
5016491	27620732	SX	2	have performed the experiments	have performed the experiments	Performed the experiments	Investigation	YES
5016491	27620732	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5609065	28934929	BTL	PLoS52	designed the experiments|designed the molecular barcodes|conducted the experiments|wrote the analysis algorithms|analyzed the data|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5609065	28934929	BTL	PLoS52	designed the experiments|designed the molecular barcodes|conducted the experiments|wrote the analysis algorithms|analyzed the data|wrote the manuscript	designed the molecular barcodes	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5609065	28934929	BTL	PLoS52	designed the experiments|designed the molecular barcodes|conducted the experiments|wrote the analysis algorithms|analyzed the data|wrote the manuscript	conducted the experiments	Performed the experiments	Investigation	YES
5609065	28934929	BTL	PLoS52	designed the experiments|designed the molecular barcodes|conducted the experiments|wrote the analysis algorithms|analyzed the data|wrote the manuscript	wrote the analysis algorithms	Contributed reagents/materials/analysis tools|Wrote the paper	Software|Writing - Original Draft	YES
5609065	28934929	BTL	PLoS52	designed the experiments|designed the molecular barcodes|conducted the experiments|wrote the analysis algorithms|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5609065	28934929	BTL	PLoS52	designed the experiments|designed the molecular barcodes|conducted the experiments|wrote the analysis algorithms|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5609065	28934929	HPJ	PLoS52	designed the experiments|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5609065	28934929	HPJ	PLoS52	designed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4190929	25302056	ESC	2	were significant manuscript writers|participated in the concept and design|participated in data analysis and interpretation	were significant manuscript writers	Wrote the paper	Writing - Original Draft	YES
4190929	25302056	ESC	2	were significant manuscript writers|participated in the concept and design|participated in data analysis and interpretation	participated in the concept and design	Conceived and designed the experiments	Conceptualization	YES
4190929	25302056	ESC	2	were significant manuscript writers|participated in the concept and design|participated in data analysis and interpretation	participated in data analysis and interpretation	Analyzed the data	Formal analysis	YES
4190929	25302056	HB	2	were significant manuscript writers|participated in the concept and design|were responsible for data acquisition|participated in data analysis and interpretation	were significant manuscript writers	Wrote the paper	Writing - Original Draft	YES
4190929	25302056	HB	2	were significant manuscript writers|participated in the concept and design|were responsible for data acquisition|participated in data analysis and interpretation	participated in the concept and design	Conceived and designed the experiments	Conceptualization	YES
4190929	25302056	HB	2	were significant manuscript writers|participated in the concept and design|were responsible for data acquisition|participated in data analysis and interpretation	were responsible for data acquisition	Performed the experiments	Investigation	YES
4190929	25302056	HB	2	were significant manuscript writers|participated in the concept and design|were responsible for data acquisition|participated in data analysis and interpretation	participated in data analysis and interpretation	Analyzed the data	Formal analysis	YES
4190929	25302056	LRA	2	were significant manuscript writers|participated in the concept and design|participated in data analysis and interpretation	were significant manuscript writers	Wrote the paper	Writing - Original Draft	YES
4190929	25302056	LRA	2	were significant manuscript writers|participated in the concept and design|participated in data analysis and interpretation	participated in the concept and design	Conceived and designed the experiments	Conceptualization	YES
4190929	25302056	LRA	2	were significant manuscript writers|participated in the concept and design|participated in data analysis and interpretation	participated in data analysis and interpretation	Analyzed the data	Formal analysis	YES
4190929	25302056	MVC	2	were significant manuscript writers|were responsible for data acquisition|participated in data analysis and interpretation	were significant manuscript writers	Wrote the paper	Writing - Original Draft	YES
4190929	25302056	MVC	2	were significant manuscript writers|were responsible for data acquisition|participated in data analysis and interpretation	were responsible for data acquisition	Performed the experiments	Investigation	YES
4190929	25302056	MVC	2	were significant manuscript writers|were responsible for data acquisition|participated in data analysis and interpretation	participated in data analysis and interpretation	Analyzed the data	Formal analysis	YES
6115323	30159686	AB	2	were involved in interpretation of data|drafted the manuscript	were involved in interpretation of data	Analyzed the data	Formal analysis	YES
6115323	30159686	AB	2	were involved in interpretation of data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
6115323	30159686	CT	2	collection of data	collection of data	Performed the experiments	Investigation	YES
6115323	30159686	ES	2	were responsible for data analysis and statistics|were involved in interpretation of data|drafted the manuscript	were responsible for data analysis and statistics	Analyzed the data	Formal analysis	YES
6115323	30159686	ES	2	were responsible for data analysis and statistics|were involved in interpretation of data|drafted the manuscript	were involved in interpretation of data	Analyzed the data	Formal analysis	YES
6115323	30159686	ES	2	were responsible for data analysis and statistics|were involved in interpretation of data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
6115323	30159686	GC	2	was responsible for the selection of the patients	was responsible for the selection of the patients	-	-	NO
6115323	30159686	GR	2	were responsible for data analysis and statistics|were involved in interpretation of data	were responsible for data analysis and statistics	Analyzed the data	Formal analysis	YES
6115323	30159686	GR	2	were responsible for data analysis and statistics|were involved in interpretation of data	were involved in interpretation of data	Analyzed the data	Formal analysis	YES
6115323	30159686	LI	2	were responsible for the conception and design of the study|were involved in interpretation of data|contributed to the manuscript	were responsible for the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6115323	30159686	LI	2	were responsible for the conception and design of the study|were involved in interpretation of data|contributed to the manuscript	were involved in interpretation of data	Analyzed the data	Formal analysis	YES
6115323	30159686	LI	2	were responsible for the conception and design of the study|were involved in interpretation of data|contributed to the manuscript	contributed to the manuscript	-	-	NO
6115323	30159686	MC	2	were responsible for data analysis and statistics	were responsible for data analysis and statistics	Analyzed the data	Formal analysis	YES
6115323	30159686	MLC	2	were responsible for the conception and design of the study|were involved in interpretation of data|drafted the manuscript	were responsible for the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6115323	30159686	MLC	2	were responsible for the conception and design of the study|were involved in interpretation of data|drafted the manuscript	were involved in interpretation of data	Analyzed the data	Formal analysis	YES
6115323	30159686	MLC	2	were responsible for the conception and design of the study|were involved in interpretation of data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
6115323	30159686	MVM	2	contributed to the manuscript	contributed to the manuscript	-	-	NO
6115323	30159686	PG	2	was involved in histological analysis	was involved in histological analysis	Performed the experiments	Investigation	YES
6115323	30159686	VS	2	were involved in interpretation of data|drafted the manuscript	were involved in interpretation of data	Analyzed the data	Formal analysis	YES
6115323	30159686	VS	2	were involved in interpretation of data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4414539	25923810	CD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414539	25923810	CD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414539	25923810	CD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414539	25923810	CD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414539	25923810	DL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4414539	25923810	MZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414539	25923810	MZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414539	25923810	MZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414539	25923810	MZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414539	25923810	TG	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414539	25923810	XK	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414539	25923810	XK	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414539	25923810	XL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1904252	17622354	XC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1904252	17622354	XC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1904252	17622354	XC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1904252	17622354	XC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1904252	17622354	XC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5732936	29312385	B-RL	2	carried out the experiment|participated in data interpretation and critical reading of the manuscript	carried out the experiment	Performed the experiments	Investigation	YES
5732936	29312385	B-RL	2	carried out the experiment|participated in data interpretation and critical reading of the manuscript	participated in data interpretation and critical reading of the manuscript	Analyzed the data	Formal analysis	YES
5732936	29312385	D-WB	2	participated in data interpretation and critical reading of the manuscript	participated in data interpretation and critical reading of the manuscript	Analyzed the data	Formal analysis	YES
5732936	29312385	MTI	2	designed the experiment and wrote the manuscript|carried out the experiment	designed the experiment and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5732936	29312385	MTI	2	designed the experiment and wrote the manuscript|carried out the experiment	carried out the experiment	Performed the experiments	Investigation	YES
5732936	29312385	S-HP	2	participated in data interpretation and critical reading of the manuscript	participated in data interpretation and critical reading of the manuscript	Analyzed the data	Formal analysis	YES
5732936	29312385	T-HK	2	designed the experiment and wrote the manuscript|participated in data interpretation and critical reading of the manuscript	designed the experiment and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5732936	29312385	T-HK	2	designed the experiment and wrote the manuscript|participated in data interpretation and critical reading of the manuscript	participated in data interpretation and critical reading of the manuscript	Analyzed the data	Formal analysis	YES
5732936	29312385	VHL	2	participated in data interpretation and critical reading of the manuscript	participated in data interpretation and critical reading of the manuscript	Analyzed the data	Formal analysis	YES
1904253	17622344	NU	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1904253	17622344	SA	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5019992	27620736	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5019992	27620736	GW	2	was the group leader providing financial support and supervision	was the group leader providing financial support and supervision	-	Funding acquisition|Supervision	YES
5019992	27620736	IEC	2	for animal experiment from medical school, southeast university	for animal experiment from medical school, southeast university	Performed the experiments	Investigation	YES
5019992	27620736	Ms Q. Qu	2	who was in response of the animal experiment had taken the experimental animal training and received the certificate from nanjing medical university	who was in response of the animal experiment had taken the experimental animal training and received the certificate from nanjing medical university	Performed the experiments	Investigation	YES
5019992	27620736	QQ	2	did the animal experiments	did the animal experiments	Performed the experiments	Investigation	YES
5019992	27620736	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5019992	27620736	XF	2	revised the manuscript and funded this study	revised the manuscript and funded this study	Wrote the paper	Funding acquisition|Writing - Review & Editing	YES
5019992	27620736	XX	2	did most of the experiments and prepared the manuscript	did most of the experiments and prepared the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6127070	30191351	AN	2	carried out the immunohistochemical analysis	carried out the immunohistochemical analysis	Performed the experiments	Investigation	YES
6127070	30191351	AR	2	participated in the data acquisition and statistical analysis	participated in the data acquisition and statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6127070	30191351	HJW	2	participated in the design of the study and helped to draft the manuscript	participated in the design of the study and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
6127070	30191351	JE	2	participated in the study design and coordination and data acquisition	participated in the study design and coordination and data acquisition	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Project administration	YES
6127070	30191351	KS	2	carried out the immunohistochemical studies	carried out the immunohistochemical studies	Performed the experiments	Investigation	YES
6127070	30191351	MN	2	participated in the data acquisition and study coordination and helped to draft the manuscript	participated in the data acquisition and study coordination and helped to draft the manuscript	Performed the experiments|Wrote the paper	Investigation|Project administration|Writing - Original Draft	YES
6127070	30191351	MS	2	conceived of the study, participated in the design of the study, and helped to draft the manuscript	conceived of the study, participated in the design of the study, and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
6127070	30191351	PH	2	participated in the design of the study and helped to draft the manuscript	participated in the design of the study and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
6127070	30191351	TV	2	participated in the design of the study and in the data acquisition and drafted the manuscript	participated in the design of the study and in the data acquisition and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
6127070	30191351	UK	2	participated in the design of the study and helped to draft the manuscript	participated in the design of the study and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4190931	25302057	DB	7	design of the study, revising manuscript	design of the study, revising manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
4190931	25302057	ED	7	conception and design of the study, acquisition of data, revising manuscript	conception and design of the study, acquisition of data, revising manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Writing - Review & Editing	YES
4190931	25302057	GE	7	acquisition of data, analysis and interpretation of data, revising manuscript	acquisition of data, analysis and interpretation of data, revising manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
4190931	25302057	JL	7	conception and design of the study, revising manuscript	conception and design of the study, revising manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
4190931	25302057	LM	7	acquisition of data, dietary protocol management, revising manuscript	acquisition of data, dietary protocol management, revising manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
4190931	25302057	MD	7	conception and design of the study (main clinical investigator), acquisition of data, revising manuscript	conception and design of the study (main clinical investigator), acquisition of data, revising manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Review & Editing	YES
4190931	25302057	NA	7	analysis and interpretation of data, revising manuscript	analysis and interpretation of data, revising manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4190931	25302057	PL	7	conception and design of the study, acquisition of data, analysis and interpretation of data, revising manuscript	conception and design of the study, acquisition of data, analysis and interpretation of data, revising manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Review & Editing	YES
4190931	25302057	PS	7	conception and design of the study (main project coordinator), acquisition of data, analysis and interpretation of data, drafting manuscript	conception and design of the study (main project coordinator), acquisition of data, analysis and interpretation of data, drafting manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Project administration|Writing - Original Draft	YES
4190931	25302057	SP	7	conception and design of the study (main project coordinator), analysis and interpretation of data, statistical analysis, drafting manuscript	conception and design of the study (main project coordinator), analysis and interpretation of data, statistical analysis, drafting manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Project administration|Writing - Original Draft	YES
4190931	25302057	SR	7	conception and design of the study, acquisition of data (electromyographic measures), analysis and interpretation of data (electromyographic measures), drafting manuscript	conception and design of the study, acquisition of data (electromyographic measures), analysis and interpretation of data (electromyographic measures), drafting manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4190931	25302057	TB	7	conception and design of the study, acquisition of data, analysis and interpretation of data, drafting manuscript	conception and design of the study, acquisition of data, analysis and interpretation of data, drafting manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4190931	25302057	VM	7	analysis and interpretation of data (electromyographic measures), revising manuscript	analysis and interpretation of data (electromyographic measures), revising manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
5610437	28938871	FC	2	conceived and designed the project	conceived and designed the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5610437	28938871	JC	2	performed the histological examination of the regeneration limb	performed the histological examination of the regeneration limb	Performed the experiments	Investigation	YES
5610437	28938871	JT	2	analyzed and interpreted the itraq data and was a major contributor in writing the manuscript|planned and executed experiments	analyzed and interpreted the itraq data and was a major contributor in writing the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5610437	28938871	JT	2	analyzed and interpreted the itraq data and was a major contributor in writing the manuscript|planned and executed experiments	planned and executed experiments	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5610437	28938871	LY	2	planned and executed experiments	planned and executed experiments	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5610437	28938871	MS	2	planned and executed experiments	planned and executed experiments	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5610437	28938871	YY	2	planned and executed experiments	planned and executed experiments	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
4414540	25923974	JG	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4414540	25923974	JG	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414540	25923974	JL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4414540	25923974	LZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414540	25923974	LZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414540	25923974	LZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414540	25923974	NL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4414540	25923974	NL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4414540	25923974	NL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414540	25923974	XZ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4414540	25923974	XZ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4414540	25923974	XZ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414540	25923974	YH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414540	25923974	YH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414540	25923974	YH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414540	25923974	YH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414540	25923974	ZD	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414540	25923974	ZD	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414540	25923974	ZD	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1904254	17622347	FS	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1904254	17622347	FS	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1904254	17622347	HH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1904254	17622347	HH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1904254	17622347	HH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1904254	17622347	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1904254	17622347	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1904254	17622347	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1904254	17622347	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1904254	17622347	MM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1904254	17622347	MM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1904254	17622347	MM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1904254	17622347	OC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1904254	17622347	OC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1904254	17622347	OC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1904254	17622347	RR	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1904254	17622347	RR	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5732959	29312383	JT	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5732959	29312383	XW	2	designed the study|prepared materials, performed most of experiments, and wrote the original manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5732959	29312383	XW	2	designed the study|prepared materials, performed most of experiments, and wrote the original manuscript	prepared materials, performed most of experiments, and wrote the original manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6131687	30203138	AG	2	helped with the data analysis	helped with the data analysis	Analyzed the data	Formal analysis	YES
6131687	30203138	AH	2	helped with the data analysis	helped with the data analysis	Analyzed the data	Formal analysis	YES
6131687	30203138	All authors	2	contributed to the drafting of the manuscript, and all authors read and approved the final manuscript	contributed to the drafting of the manuscript, and all authors read and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6131687	30203138	BS	2	contributed to the concept and design of the study	contributed to the concept and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6131687	30203138	EM	2	contributed to the implementation of the voxel-wise analysis	contributed to the implementation of the voxel-wise analysis	Performed the experiments	Investigation	YES
6131687	30203138	FWK	2	were in charge of the neuropathological diagnosis according to biopsy or resection	were in charge of the neuropathological diagnosis according to biopsy or resection	Performed the experiments	Investigation	YES
6131687	30203138	GB	2	contributed to the concept and design of the study|contributed to the implementation of the voxel-wise analysis	contributed to the concept and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6131687	30203138	GB	2	contributed to the concept and design of the study|contributed to the implementation of the voxel-wise analysis	contributed to the implementation of the voxel-wise analysis	Performed the experiments	Investigation	YES
6131687	30203138	JB	2	helped with the data analysis	helped with the data analysis	Analyzed the data	Formal analysis	YES
6131687	30203138	JCT	2	were in charge of the neuropathological diagnosis according to biopsy or resection	were in charge of the neuropathological diagnosis according to biopsy or resection	Performed the experiments	Investigation	YES
6131687	30203138	LV	2	contributed to the concept and design of the study|implemented the voxel-wise analysis, performed the global data and statistical analysis, and drafted the manuscript	contributed to the concept and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6131687	30203138	LV	2	contributed to the concept and design of the study|implemented the voxel-wise analysis, performed the global data and statistical analysis, and drafted the manuscript	implemented the voxel-wise analysis, performed the global data and statistical analysis, and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6131687	30203138	MU	2	contributed to the concept and design of the study	contributed to the concept and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6131687	30203138	NLA	2	contributed to the concept and design of the study	contributed to the concept and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6131687	30203138	PB	2	contributed to the concept and design of the study	contributed to the concept and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6131687	30203138	SZ	2	contributed to the concept and design of the study	contributed to the concept and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5020000	27620734	BCES	1	Acquisition of data|Drafting of manuscript	Acquisition of data	Performed the experiments	Investigation	YES
5020000	27620734	BCES	1	Acquisition of data|Drafting of manuscript	Drafting of manuscript	Wrote the paper	Writing - Original Draft	YES
5020000	27620734	GC	1	Acquisition of data|Analysis and interpretation of data	Acquisition of data	Performed the experiments	Investigation	YES
5020000	27620734	GC	1	Acquisition of data|Analysis and interpretation of data	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
5020000	27620734	IMD	1	Analysis and interpretation of data|Drafting of manuscript|Critical revision	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
5020000	27620734	IMD	1	Analysis and interpretation of data|Drafting of manuscript|Critical revision	Drafting of manuscript	Wrote the paper	Writing - Original Draft	YES
5020000	27620734	IMD	1	Analysis and interpretation of data|Drafting of manuscript|Critical revision	Critical revision	Wrote the paper	Writing - Review & Editing	YES
5020000	27620734	LDT	1	Acquisition of data	Acquisition of data	Performed the experiments	Investigation	YES
5020000	27620734	LPP	1	Acquisition of data|Analysis and interpretation of data|Drafting of manuscript|Critical revision	Acquisition of data	Performed the experiments	Investigation	YES
5020000	27620734	LPP	1	Acquisition of data|Analysis and interpretation of data|Drafting of manuscript|Critical revision	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
5020000	27620734	LPP	1	Acquisition of data|Analysis and interpretation of data|Drafting of manuscript|Critical revision	Drafting of manuscript	Wrote the paper	Writing - Original Draft	YES
5020000	27620734	LPP	1	Acquisition of data|Analysis and interpretation of data|Drafting of manuscript|Critical revision	Critical revision	Wrote the paper	Writing - Review & Editing	YES
5020000	27620734	LRO	1	Acquisition of data|Analysis and interpretation of data|Drafting of manuscript|Critical revision	Acquisition of data	Performed the experiments	Investigation	YES
5020000	27620734	LRO	1	Acquisition of data|Analysis and interpretation of data|Drafting of manuscript|Critical revision	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
5020000	27620734	LRO	1	Acquisition of data|Analysis and interpretation of data|Drafting of manuscript|Critical revision	Drafting of manuscript	Wrote the paper	Writing - Original Draft	YES
5020000	27620734	LRO	1	Acquisition of data|Analysis and interpretation of data|Drafting of manuscript|Critical revision	Critical revision	Wrote the paper	Writing - Review & Editing	YES
5020000	27620734	MJS	1	Analysis and interpretation of data|Drafting of manuscript|Critical revision	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
5020000	27620734	MJS	1	Analysis and interpretation of data|Drafting of manuscript|Critical revision	Drafting of manuscript	Wrote the paper	Writing - Original Draft	YES
5020000	27620734	MJS	1	Analysis and interpretation of data|Drafting of manuscript|Critical revision	Critical revision	Wrote the paper	Writing - Review & Editing	YES
5020000	27620734	MND	1	Analysis and interpretation of data|Drafting of manuscript|Critical revision	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
5020000	27620734	MND	1	Analysis and interpretation of data|Drafting of manuscript|Critical revision	Drafting of manuscript	Wrote the paper	Writing - Original Draft	YES
5020000	27620734	MND	1	Analysis and interpretation of data|Drafting of manuscript|Critical revision	Critical revision	Wrote the paper	Writing - Review & Editing	YES
5020000	27620734	MP	1	Analysis and interpretation of data|Drafting of manuscript|Critical revision	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
5020000	27620734	MP	1	Analysis and interpretation of data|Drafting of manuscript|Critical revision	Drafting of manuscript	Wrote the paper	Writing - Original Draft	YES
5020000	27620734	MP	1	Analysis and interpretation of data|Drafting of manuscript|Critical revision	Critical revision	Wrote the paper	Writing - Review & Editing	YES
5020000	27620734	PFM	1	Acquisition of data|Analysis and interpretation of data|Critical revision	Acquisition of data	Performed the experiments	Investigation	YES
5020000	27620734	PFM	1	Acquisition of data|Analysis and interpretation of data|Critical revision	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
5020000	27620734	PFM	1	Acquisition of data|Analysis and interpretation of data|Critical revision	Critical revision	Wrote the paper	Writing - Review & Editing	YES
5020000	27620734	PMR	1	Analysis and interpretation of data|Drafting of manuscript|Critical revision	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
5020000	27620734	PMR	1	Analysis and interpretation of data|Drafting of manuscript|Critical revision	Drafting of manuscript	Wrote the paper	Writing - Original Draft	YES
5020000	27620734	PMR	1	Analysis and interpretation of data|Drafting of manuscript|Critical revision	Critical revision	Wrote the paper	Writing - Review & Editing	YES
5020000	27620734	RAA	1	Analysis and interpretation of data|Drafting of manuscript|Critical revision	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
5020000	27620734	RAA	1	Analysis and interpretation of data|Drafting of manuscript|Critical revision	Drafting of manuscript	Wrote the paper	Writing - Original Draft	YES
5020000	27620734	RAA	1	Analysis and interpretation of data|Drafting of manuscript|Critical revision	Critical revision	Wrote the paper	Writing - Review & Editing	YES
5020000	27620734	RAP	1	Analysis and interpretation of data|Drafting of manuscript|Critical revision	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
5020000	27620734	RAP	1	Analysis and interpretation of data|Drafting of manuscript|Critical revision	Drafting of manuscript	Wrote the paper	Writing - Original Draft	YES
5020000	27620734	RAP	1	Analysis and interpretation of data|Drafting of manuscript|Critical revision	Critical revision	Wrote the paper	Writing - Review & Editing	YES
5020000	27620734	SAVP	1	Analysis and interpretation of data|Drafting of manuscript|Critical revision	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
5020000	27620734	SAVP	1	Analysis and interpretation of data|Drafting of manuscript|Critical revision	Drafting of manuscript	Wrote the paper	Writing - Original Draft	YES
5020000	27620734	SAVP	1	Analysis and interpretation of data|Drafting of manuscript|Critical revision	Critical revision	Wrote the paper	Writing - Review & Editing	YES
4414541	25923429	EM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4414541	25923429	KB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414541	25923429	KB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4414541	25923429	KB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4414541	25923429	KN	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4414541	25923429	MSa	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414541	25923429	MSa	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4414541	25923429	MSz	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414541	25923429	PWA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414541	25923429	PWA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414541	25923429	PWA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414541	25923429	WP	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414541	25923429	WP	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1904255	17622348	CT	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1904255	17622348	CT	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1904255	17622348	CT	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1904255	17622348	RE	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1904255	17622348	RE	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1904255	17622348	RE	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5610441	28938868	AS-LC	2	produced and analyzed the hcc data	produced and analyzed the hcc data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5610441	28938868	BK	2	conceived the study|designed stql|wrote the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5610441	28938868	BK	2	conceived the study|designed stql|wrote the manuscript	designed stql	Conceived and designed the experiments	-	YES
5610441	28938868	BK	2	conceived the study|designed stql|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5610441	28938868	EL	2	conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5610441	28938868	KH-OY	2	produced and analyzed the hcc data	produced and analyzed the hcc data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5610441	28938868	KYY	2	conceived the study|designed stql|produced and analyzed the hcc data|wrote the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5610441	28938868	KYY	2	conceived the study|designed stql|produced and analyzed the hcc data|wrote the manuscript	designed stql	Conceived and designed the experiments	-	YES
5610441	28938868	KYY	2	conceived the study|designed stql|produced and analyzed the hcc data|wrote the manuscript	produced and analyzed the hcc data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5610441	28938868	KYY	2	conceived the study|designed stql|produced and analyzed the hcc data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5610441	28938868	STQL	2	with other languages and systems	with other languages and systems	-	-	NO
5610441	28938868	THH	2	produced and analyzed the hcc data	produced and analyzed the hcc data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5610441	28938868	XZ	2	designed stql|wrote the manuscript	designed stql	Conceived and designed the experiments	-	YES
5610441	28938868	XZ	2	designed stql|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5732962	29312390	HJ	PLoS52	wrote the manuscript|performed the experiments	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5732962	29312390	HJ	PLoS52	wrote the manuscript|performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5732962	29312390	JX	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5732962	29312390	NW	PLoS52	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5732962	29312390	VO	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5732962	29312390	YZ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
4414544	25923732	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414544	25923732	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414544	25923732	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414544	25923732	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414544	25923732	JHL	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4414544	25923732	MS	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414544	25923732	MS	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4414544	25923732	NR	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4414544	25923732	NS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4414544	25923732	NS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414544	25923732	SRC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414544	25923732	SRC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414544	25923732	SRC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414544	25923732	SRC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414544	25923732	TA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414544	25923732	TA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414544	25923732	TA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414544	25923732	TA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6141411	30225682	AM	2	participated in the design of the study and data acquisition|participated in the data analysis and revised the manuscript	participated in the design of the study and data acquisition	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6141411	30225682	AM	2	participated in the design of the study and data acquisition|participated in the data analysis and revised the manuscript	participated in the data analysis and revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
6141411	30225682	DA	2	participated in the design of the study and data acquisition|participated in the data analysis and revised the manuscript	participated in the design of the study and data acquisition	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6141411	30225682	DA	2	participated in the design of the study and data acquisition|participated in the data analysis and revised the manuscript	participated in the data analysis and revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
6141411	30225682	DMG	2	participated in the data analysis and revised the manuscript	participated in the data analysis and revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
6141411	30225682	FB	2	participated in the design of the study and data acquisition, performed the statistical analysis, and drafted the manuscript	participated in the design of the study and data acquisition, performed the statistical analysis, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5020004	27620733	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5020004	27620733	CA	2	have conceived and designed the experiments|have performed the experiments|have analyzed the data|have contributed reagents/analysis tools|have written the research paper	have conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5020004	27620733	CA	2	have conceived and designed the experiments|have performed the experiments|have analyzed the data|have contributed reagents/analysis tools|have written the research paper	have performed the experiments	Performed the experiments	Investigation	YES
5020004	27620733	CA	2	have conceived and designed the experiments|have performed the experiments|have analyzed the data|have contributed reagents/analysis tools|have written the research paper	have analyzed the data	Analyzed the data	Formal analysis	YES
5020004	27620733	CA	2	have conceived and designed the experiments|have performed the experiments|have analyzed the data|have contributed reagents/analysis tools|have written the research paper	have contributed reagents/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5020004	27620733	CA	2	have conceived and designed the experiments|have performed the experiments|have analyzed the data|have contributed reagents/analysis tools|have written the research paper	have written the research paper	Wrote the paper	Writing - Original Draft	YES
5020004	27620733	PBS	2	have conceived and designed the experiments|have performed the experiments|have analyzed the data|have written the research paper	have conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5020004	27620733	PBS	2	have conceived and designed the experiments|have performed the experiments|have analyzed the data|have written the research paper	have performed the experiments	Performed the experiments	Investigation	YES
5020004	27620733	PBS	2	have conceived and designed the experiments|have performed the experiments|have analyzed the data|have written the research paper	have analyzed the data	Analyzed the data	Formal analysis	YES
5020004	27620733	PBS	2	have conceived and designed the experiments|have performed the experiments|have analyzed the data|have written the research paper	have written the research paper	Wrote the paper	Writing - Original Draft	YES
5020004	27620733	SRJ	2	have conceived and designed the experiments|have analyzed the data|have contributed reagents/analysis tools|have written the research paper	have conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5020004	27620733	SRJ	2	have conceived and designed the experiments|have analyzed the data|have contributed reagents/analysis tools|have written the research paper	have analyzed the data	Analyzed the data	Formal analysis	YES
5020004	27620733	SRJ	2	have conceived and designed the experiments|have analyzed the data|have contributed reagents/analysis tools|have written the research paper	have contributed reagents/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5020004	27620733	SRJ	2	have conceived and designed the experiments|have analyzed the data|have contributed reagents/analysis tools|have written the research paper	have written the research paper	Wrote the paper	Writing - Original Draft	YES
1904256	17622350	AL	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1904256	17622350	AL	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1904256	17622350	TG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1904256	17622350	TG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1904256	17622350	TG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1904256	17622350	TG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414545	25923803	BVE	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4414545	25923803	BVE	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414545	25923803	DMP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4414545	25923803	EAS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414545	25923803	EAS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414545	25923803	EAS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414545	25923803	EAS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414545	25923803	IAD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414545	25923803	IAD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4414545	25923803	IAD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414545	25923803	NKF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414545	25923803	NKF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414545	25923803	NKF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414545	25923803	NKF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414545	25923803	NNK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414545	25923803	NNK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414545	25923803	NNK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414545	25923803	NNK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414545	25923803	VAB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
3842066	24324385	Both authors	2	read and approved the final paper	read and approved the final paper	-	-	NO
3842066	24324385	Chengping Lu	2	designed the study|supervised the study and contributed to writing the paper	designed the study	Conceived and designed the experiments	Methodology	YES
3842066	24324385	Chengping Lu	2	designed the study|supervised the study and contributed to writing the paper	supervised the study and contributed to writing the paper	Wrote the paper	Supervision|Writing - Original Draft	YES
3842066	24324385	Hongjie Fan	2	supervised the study and contributed to writing the paper	supervised the study and contributed to writing the paper	Wrote the paper	Supervision|Writing - Original Draft	YES
3842066	24324385	Li Yi	2	performed most of the experiments, analysed the data, provided figures and tables, and writing the paper|contributed equally to this work	performed most of the experiments, analysed the data, provided figures and tables, and writing the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Visualization|Writing - Original Draft	YES
3842066	24324385	Li Yi	2	performed most of the experiments, analysed the data, provided figures and tables, and writing the paper|contributed equally to this work	contributed equally to this work	-	-	NO
3842066	24324385	Xiangchao Cheng	2	did some experiments and analysed data	did some experiments and analysed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3842066	24324385	Yang Wang	2	designed the study|performed most of the experiments, analysed the data, provided figures and tables, and writing the paper|contributed equally to this work	designed the study	Conceived and designed the experiments	Methodology	YES
3842066	24324385	Yang Wang	2	designed the study|performed most of the experiments, analysed the data, provided figures and tables, and writing the paper|contributed equally to this work	performed most of the experiments, analysed the data, provided figures and tables, and writing the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Visualization|Writing - Original Draft	YES
3842066	24324385	Yang Wang	2	designed the study|performed most of the experiments, analysed the data, provided figures and tables, and writing the paper|contributed equally to this work	contributed equally to this work	-	-	NO
3842066	24324385	Zhicheng Zhang	2	did some experiments and analysed data	did some experiments and analysed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5732984	29312373	HLP	7	performed the experiments and conducted bioinformatics analyses|analyzed the data, and wrote the manuscript	performed the experiments and conducted bioinformatics analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5732984	29312373	HLP	7	performed the experiments and conducted bioinformatics analyses|analyzed the data, and wrote the manuscript	analyzed the data, and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5732984	29312373	M-HC	7	conceived and designed the experiments|performed the experiments and conducted bioinformatics analyses|analyzed the data, and wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5732984	29312373	M-HC	7	conceived and designed the experiments|performed the experiments and conducted bioinformatics analyses|analyzed the data, and wrote the manuscript	performed the experiments and conducted bioinformatics analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5732984	29312373	M-HC	7	conceived and designed the experiments|performed the experiments and conducted bioinformatics analyses|analyzed the data, and wrote the manuscript	analyzed the data, and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5732984	29312373	MK	7	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5732984	29312373	S-WL	7	conceived and designed the experiments|analyzed the data, and wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5732984	29312373	S-WL	7	conceived and designed the experiments|analyzed the data, and wrote the manuscript	analyzed the data, and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5732984	29312373	SHB	7	analyzed the data, and wrote the manuscript	analyzed the data, and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5610455	28938869	GA	7	Data collection, analysis and manuscript preparation	Data collection, analysis and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5610455	28938869	LVC	7	Data collection, data analysis and manuscript preparation	Data collection, data analysis and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5610455	28938869	MAS	7	Conceived, planned and supervised experiments, manuscript preparation	Conceived, planned and supervised experiments, manuscript preparation	Conceived and designed the experiments|Wrote the paper	Conceptualization|Supervision|Writing - Original Draft	YES
5610455	28938869	SP	7	Data analysis and manuscript preparation	Data analysis and manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5610455	28938869	WT	7	Supervision and planning of experiments, and manuscript preparation	Supervision and planning of experiments, and manuscript preparation	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Original Draft	YES
5610455	28938869	ZPH	7	Data collection	Data collection	Performed the experiments	Investigation	YES
6167271	30276498	All authors	5	have participated in one or more of the following: (1) conception and design or analysis and interpretation of data	have participated in one or more of the following: (1) conception and design or analysis and interpretation of data	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
1904257	17622351	JJ	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1904257	17622351	JP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1904257	17622351	JP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1904257	17622351	JP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1904257	17622351	JP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1904257	17622351	SH	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1904257	17622351	SH	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1904257	17622351	VL	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1904257	17622351	VL	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414546	25923519	QY	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4414546	25923519	QY	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4414546	25923519	WY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414546	25923519	WY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414546	25923519	WY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414546	25923519	WY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414546	25923519	WY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414546	25923519	XC	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414546	25923519	YC	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414546	25923519	YZ	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5020028	27620735	Both authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5020028	27620735	MM	PLoS52	designed the experiments, analysed the results and wrote the manuscript	designed the experiments, analysed the results and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5020028	27620735	MMG	PLoS52	designed the experiments, analysed the results and wrote the manuscript|performed the experiments	designed the experiments, analysed the results and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5020028	27620735	MMG	PLoS52	designed the experiments, analysed the results and wrote the manuscript|performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
4609518	26504829	Christian Aalkjaer	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
4609518	26504829	Vladimir V. Matchkov	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
5732986	29312380	All authors	2	read and approved the manuscript	read and approved the manuscript	-	-	NO
6173675	30291527	HO	2	conducted examinations and patient follow-up	conducted examinations and patient follow-up	Performed the experiments	Investigation	YES
6173675	30291527	IT	2	conducted examinations and patient follow-up	conducted examinations and patient follow-up	Performed the experiments	Investigation	YES
6173675	30291527	KH	2	provided a semi-automated technique and contributed to the design of the study	provided a semi-automated technique and contributed to the design of the study	Conceived and designed the experiments	Methodology	YES
6173675	30291527	KK	2	conducted examinations and patient follow-up	conducted examinations and patient follow-up	Performed the experiments	Investigation	YES
6173675	30291527	MN	2	conducted examinations and patient follow-up	conducted examinations and patient follow-up	Performed the experiments	Investigation	YES
6173675	30291527	NO-NM	2	critically contributed to the manuscript	critically contributed to the manuscript	-	-	NO
6173675	30291527	OM	2	designed the study, collected and analyzed data, and contributed to the manuscript preparation	designed the study, collected and analyzed data, and contributed to the manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
6173675	30291527	SF	2	collected and analyzed data and contributed to the manuscript preparation	collected and analyzed data and contributed to the manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6173675	30291527	TA	2	conducted examinations and patient follow-up|critically contributed to the manuscript	conducted examinations and patient follow-up	Performed the experiments	Investigation	YES
6173675	30291527	TA	2	conducted examinations and patient follow-up|critically contributed to the manuscript	critically contributed to the manuscript	-	-	NO
6173675	30291527	TS	2	critically contributed to the manuscript	critically contributed to the manuscript	-	-	NO
1904258	17622352	CR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1904258	17622352	CR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1904258	17622352	CR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1904258	17622352	CR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1904258	17622352	CR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1904258	17622352	ER	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1904258	17622352	ER	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1904258	17622352	ER	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1904258	17622352	ER	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1904258	17622352	PW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1904258	17622352	PW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1904258	17622352	PW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1904258	17622352	PW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1904258	17622352	RS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1904258	17622352	RS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1904258	17622352	RS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1904258	17622352	RS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414547	25923770	BH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414547	25923770	BH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414547	25923770	BH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414547	25923770	BH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414547	25923770	BH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414547	25923770	EH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414547	25923770	EH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414547	25923770	EH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414547	25923770	EH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414547	25923770	EH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414547	25923770	EK	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414547	25923770	EK	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414547	25923770	KG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414547	25923770	KG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414547	25923770	KG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414547	25923770	MHT	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414547	25923770	MHT	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414547	25923770	MHT	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5613641	28946845	FT	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5613641	28946845	GW	PLoS52	performed sample preparation and total rna extraction	performed sample preparation and total rna extraction	Performed the experiments	Investigation	YES
5613641	28946845	HT	PLoS52	designed research	designed research	Conceived and designed the experiments	Methodology	YES
5613641	28946845	KW	PLoS52	performed sample preparation and total rna extraction	performed sample preparation and total rna extraction	Performed the experiments	Investigation	YES
5613641	28946845	LW	PLoS52	performed qrt-pcr experiment and new reagents	performed qrt-pcr experiment and new reagents	Performed the experiments	Investigation	YES
5613641	28946845	ML	PLoS52	designed research|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
5613641	28946845	ML	PLoS52	designed research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5613641	28946845	SH	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5613641	28946845	SL	PLoS52	performed qrt-pcr experiment and new reagents	performed qrt-pcr experiment and new reagents	Performed the experiments	Investigation	YES
5613641	28946845	WF	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5613641	28946845	XN	PLoS52	performed sample preparation and total rna extraction	performed sample preparation and total rna extraction	Performed the experiments	Investigation	YES
5613641	28946845	YJ	PLoS52	performed sample preparation and total rna extraction	performed sample preparation and total rna extraction	Performed the experiments	Investigation	YES
5613641	28946845	YZ	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5613641	28946845	ZL	PLoS52	designed research|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
5613641	28946845	ZL	PLoS52	designed research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5023640	27637943	SL	1	Mass spectrometric analysis results and its interpretation	Mass spectrometric analysis results and its interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4234291	24650275	DB	2	conceived the concept for the investigation and contributed significantly to the drafting of the manuscript|assisted in data collection and provided a significant contribution to composition and review of the manuscript	conceived the concept for the investigation and contributed significantly to the drafting of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
4234291	24650275	DB	2	conceived the concept for the investigation and contributed significantly to the drafting of the manuscript|assisted in data collection and provided a significant contribution to composition and review of the manuscript	assisted in data collection and provided a significant contribution to composition and review of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4234291	24650275	JA	2	was primary investigator in this study conducted the majority of testing and biochemical analysis	was primary investigator in this study conducted the majority of testing and biochemical analysis	Performed the experiments	Investigation	YES
4234291	24650275	LRM	2	conceived the concept for the investigation and contributed significantly to the drafting of the manuscript	conceived the concept for the investigation and contributed significantly to the drafting of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
4234291	24650275	TC	2	assisted in data collection and provided a significant contribution to composition and review of the manuscript	assisted in data collection and provided a significant contribution to composition and review of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5733009	29312363	AS	2	planned the experiments|analyzed the results	planned the experiments	Conceived and designed the experiments	Conceptualization	YES
5733009	29312363	AS	2	planned the experiments|analyzed the results	analyzed the results	Analyzed the data	Formal analysis	YES
5733009	29312363	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5733009	29312363	AnK	2	planned the experiments|generated nematode infected root samples, carried out gene expression studies through qrt pcr, developed transgenic lines, carried out gus analysis and rnai construct preparation|took the photographs|analyzed the results|wrote and finalized the manuscript	planned the experiments	Conceived and designed the experiments	Conceptualization	YES
5733009	29312363	AnK	2	planned the experiments|generated nematode infected root samples, carried out gene expression studies through qrt pcr, developed transgenic lines, carried out gus analysis and rnai construct preparation|took the photographs|analyzed the results|wrote and finalized the manuscript	generated nematode infected root samples, carried out gene expression studies through qrt pcr, developed transgenic lines, carried out gus analysis and rnai construct preparation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5733009	29312363	AnK	2	planned the experiments|generated nematode infected root samples, carried out gene expression studies through qrt pcr, developed transgenic lines, carried out gus analysis and rnai construct preparation|took the photographs|analyzed the results|wrote and finalized the manuscript	took the photographs	-	Visualization	YES
5733009	29312363	AnK	2	planned the experiments|generated nematode infected root samples, carried out gene expression studies through qrt pcr, developed transgenic lines, carried out gus analysis and rnai construct preparation|took the photographs|analyzed the results|wrote and finalized the manuscript	analyzed the results	Analyzed the data	Formal analysis	YES
5733009	29312363	AnK	2	planned the experiments|generated nematode infected root samples, carried out gene expression studies through qrt pcr, developed transgenic lines, carried out gus analysis and rnai construct preparation|took the photographs|analyzed the results|wrote and finalized the manuscript	wrote and finalized the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5733009	29312363	AtK	2	planned the experiments|designed and performed in silico analysis for nrrs promoters, cis-element identification|performed molecular cloning of promoters and expression based validation|took the photographs|analyzed the results|wrote and finalized the manuscript	planned the experiments	Conceived and designed the experiments	Conceptualization	YES
5733009	29312363	AtK	2	planned the experiments|designed and performed in silico analysis for nrrs promoters, cis-element identification|performed molecular cloning of promoters and expression based validation|took the photographs|analyzed the results|wrote and finalized the manuscript	designed and performed in silico analysis for nrrs promoters, cis-element identification	Conceived and designed the experiments|Performed the experiments	Formal analysis|Investigation	YES
5733009	29312363	AtK	2	planned the experiments|designed and performed in silico analysis for nrrs promoters, cis-element identification|performed molecular cloning of promoters and expression based validation|took the photographs|analyzed the results|wrote and finalized the manuscript	performed molecular cloning of promoters and expression based validation	Performed the experiments	Investigation|Validation	YES
5733009	29312363	AtK	2	planned the experiments|designed and performed in silico analysis for nrrs promoters, cis-element identification|performed molecular cloning of promoters and expression based validation|took the photographs|analyzed the results|wrote and finalized the manuscript	took the photographs	-	Visualization	YES
5733009	29312363	AtK	2	planned the experiments|designed and performed in silico analysis for nrrs promoters, cis-element identification|performed molecular cloning of promoters and expression based validation|took the photographs|analyzed the results|wrote and finalized the manuscript	analyzed the results	Analyzed the data	Formal analysis	YES
5733009	29312363	AtK	2	planned the experiments|designed and performed in silico analysis for nrrs promoters, cis-element identification|performed molecular cloning of promoters and expression based validation|took the photographs|analyzed the results|wrote and finalized the manuscript	wrote and finalized the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5733009	29312363	KS	2	planned the experiments|analyzed the results	planned the experiments	Conceived and designed the experiments	Conceptualization	YES
5733009	29312363	KS	2	planned the experiments|analyzed the results	analyzed the results	Analyzed the data	Formal analysis	YES
5733009	29312363	MA	2	analyzed the results	analyzed the results	Analyzed the data	Formal analysis	YES
5733009	29312363	PKJ	2	planned the experiments|analyzed the results|wrote and finalized the manuscript	planned the experiments	Conceived and designed the experiments	Conceptualization	YES
5733009	29312363	PKJ	2	planned the experiments|analyzed the results|wrote and finalized the manuscript	analyzed the results	Analyzed the data	Formal analysis	YES
5733009	29312363	PKJ	2	planned the experiments|analyzed the results|wrote and finalized the manuscript	wrote and finalized the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5733009	29312363	RB	2	analyzed the results	analyzed the results	Analyzed the data	Formal analysis	YES
5733009	29312363	RS	2	planned the experiments|analyzed the results	planned the experiments	Conceived and designed the experiments	Conceptualization	YES
5733009	29312363	RS	2	planned the experiments|analyzed the results	analyzed the results	Analyzed the data	Formal analysis	YES
5733009	29312363	VS	2	analyzed the results	analyzed the results	Analyzed the data	Formal analysis	YES
5618722	28954628	AB	7	knowledge transfer, critical discussion of the data, editing the manuscript	knowledge transfer, critical discussion of the data, editing the manuscript	Wrote the paper	Writing - Review & Editing	YES
5618722	28954628	AG	7	knowledge transfer, involvement in the laboratory part of the project, tissue processing	knowledge transfer, involvement in the laboratory part of the project, tissue processing	-	-	NO
5618722	28954628	HR	7	knowledge transfer, critical discussion and interpretation of data, and editing the manuscript	knowledge transfer, critical discussion and interpretation of data, and editing the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5618722	28954628	MPK	7	Concept of the study, experimental design, analysis and interpretation of data and writing the manuscript	Concept of the study, experimental design, analysis and interpretation of data and writing the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
5618722	28954628	SZ	7	Concept of the study, experimental design, analysis and interpretation of data and writing the manuscript	Concept of the study, experimental design, analysis and interpretation of data and writing the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
4414548	25923538	DM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414548	25923538	DM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414548	25923538	DM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414548	25923538	EQ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414548	25923538	EQ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4414548	25923538	EQ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414548	25923538	FQ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414548	25923538	FQ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4414548	25923538	FQ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4414548	25923538	FQ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414548	25923538	KF	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414548	25923538	KF	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414548	25923538	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414548	25923538	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414548	25923538	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414548	25923538	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414548	25923538	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414548	25923538	RF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414548	25923538	RF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4414548	25923538	RF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
6199202	30353250	All authors	PLoS52	read, revised, and approved the final manuscript	read, revised, and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6199202	30353250	JC	PLoS52	optimized the iodine staining|analyzed and interpreted the data	optimized the iodine staining	Performed the experiments	Investigation	YES
6199202	30353250	JC	PLoS52	optimized the iodine staining|analyzed and interpreted the data	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
6199202	30353250	MH	PLoS52	enabled the research and discussed outcomes	enabled the research and discussed outcomes	-	-	NO
6199202	30353250	MM	PLoS52	enabled the research and discussed outcomes	enabled the research and discussed outcomes	-	-	NO
6199202	30353250	SP	PLoS52	designed the experiments|performed the experiments|analyzed and interpreted the data|wrote the paper	designed the experiments	Conceived and designed the experiments	Methodology	YES
6199202	30353250	SP	PLoS52	designed the experiments|performed the experiments|analyzed and interpreted the data|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
6199202	30353250	SP	PLoS52	designed the experiments|performed the experiments|analyzed and interpreted the data|wrote the paper	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
6199202	30353250	SP	PLoS52	designed the experiments|performed the experiments|analyzed and interpreted the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6199202	30353250	TN	PLoS52	performed the experiments|analyzed and interpreted the data	performed the experiments	Performed the experiments	Investigation	YES
6199202	30353250	TN	PLoS52	performed the experiments|analyzed and interpreted the data	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
6199202	30353250	VP	PLoS52	established the pixel-based analysis|analyzed and interpreted the data|wrote the paper	established the pixel-based analysis	-	-	NO
6199202	30353250	VP	PLoS52	established the pixel-based analysis|analyzed and interpreted the data|wrote the paper	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
6199202	30353250	VP	PLoS52	established the pixel-based analysis|analyzed and interpreted the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6199202	30353250	WW	PLoS52	designed the experiments|analyzed and interpreted the data|wrote the paper	designed the experiments	Conceived and designed the experiments	Methodology	YES
6199202	30353250	WW	PLoS52	designed the experiments|analyzed and interpreted the data|wrote the paper	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
6199202	30353250	WW	PLoS52	designed the experiments|analyzed and interpreted the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
1905939	17637837	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1905939	17637837	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1905939	17637837	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1905939	17637837	AG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1905939	17637837	AG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1905939	17637837	AG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1905939	17637837	AM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1905939	17637837	AT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1905939	17637837	AT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1905939	17637837	AT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1905939	17637837	CB	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1905939	17637837	FL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1905939	17637837	JF	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1905939	17637837	JF	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1905939	17637837	OD	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1905939	17637837	OR	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1905939	17637837	OR	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1905939	17637837	PG	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1905939	17637837	SO	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5023641	27637944	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5023641	27637944	PL	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5023641	27637944	RX	PLoS52	prepared materials and performed the experiments|analyzed the data	prepared materials and performed the experiments	Performed the experiments	Investigation	YES
5023641	27637944	RX	PLoS52	prepared materials and performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5023641	27637944	SW	PLoS52	contributed to the design of the research|participated in the coordination and completion of the manuscript	contributed to the design of the research	Conceived and designed the experiments	Methodology	YES
5023641	27637944	SW	PLoS52	contributed to the design of the research|participated in the coordination and completion of the manuscript	participated in the coordination and completion of the manuscript	-	Project administration	YES
5023641	27637944	The authors	PLoS52	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5023641	27637944	XJD	PLoS52	contributed to the design of the research|analyzed the data|participated in the coordination and completion of the manuscript	contributed to the design of the research	Conceived and designed the experiments	Methodology	YES
5023641	27637944	XJD	PLoS52	contributed to the design of the research|analyzed the data|participated in the coordination and completion of the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5023641	27637944	XJD	PLoS52	contributed to the design of the research|analyzed the data|participated in the coordination and completion of the manuscript	participated in the coordination and completion of the manuscript	-	Project administration	YES
5023641	27637944	XZ	PLoS52	prepared materials and performed the experiments|analyzed the data	prepared materials and performed the experiments	Performed the experiments	Investigation	YES
5023641	27637944	XZ	PLoS52	prepared materials and performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
6206308	30374743	ADS	2	approved the final manuscript|were responsible for the administrative, technical, or material support	approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6206308	30374743	ADS	2	approved the final manuscript|were responsible for the administrative, technical, or material support	were responsible for the administrative, technical, or material support	Performed the experiments	Investigation|Project administration	YES
6206308	30374743	CEM	2	approved the final manuscript	approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6206308	30374743	CGR	2	approved the final manuscript|were responsible for the study supervision	approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6206308	30374743	CGR	2	approved the final manuscript|were responsible for the study supervision	were responsible for the study supervision	-	Supervision	YES
6206308	30374743	JC	2	approved the final manuscript	approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6206308	30374743	JCz	2	were responsible for the writing, review, and/or revision of the manuscript|approved the final manuscript|were responsible for the study supervision	were responsible for the writing, review, and/or revision of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6206308	30374743	JCz	2	were responsible for the writing, review, and/or revision of the manuscript|approved the final manuscript|were responsible for the study supervision	approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6206308	30374743	JCz	2	were responsible for the writing, review, and/or revision of the manuscript|approved the final manuscript|were responsible for the study supervision	were responsible for the study supervision	-	Supervision	YES
6206308	30374743	KH	2	were responsible for the writing, review, and/or revision of the manuscript|approved the final manuscript	were responsible for the writing, review, and/or revision of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6206308	30374743	KH	2	were responsible for the writing, review, and/or revision of the manuscript|approved the final manuscript	approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6206308	30374743	KL	2	were responsible for the conception and design and analysis and interpretation of data|were responsible for the acquisition of data|were responsible for the writing, review, and/or revision of the manuscript|approved the final manuscript|were responsible for the study supervision	were responsible for the conception and design and analysis and interpretation of data	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
6206308	30374743	KL	2	were responsible for the conception and design and analysis and interpretation of data|were responsible for the acquisition of data|were responsible for the writing, review, and/or revision of the manuscript|approved the final manuscript|were responsible for the study supervision	were responsible for the acquisition of data	Performed the experiments	Investigation	YES
6206308	30374743	KL	2	were responsible for the conception and design and analysis and interpretation of data|were responsible for the acquisition of data|were responsible for the writing, review, and/or revision of the manuscript|approved the final manuscript|were responsible for the study supervision	were responsible for the writing, review, and/or revision of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6206308	30374743	KL	2	were responsible for the conception and design and analysis and interpretation of data|were responsible for the acquisition of data|were responsible for the writing, review, and/or revision of the manuscript|approved the final manuscript|were responsible for the study supervision	approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6206308	30374743	KL	2	were responsible for the conception and design and analysis and interpretation of data|were responsible for the acquisition of data|were responsible for the writing, review, and/or revision of the manuscript|approved the final manuscript|were responsible for the study supervision	were responsible for the study supervision	-	Supervision	YES
6206308	30374743	LW	2	were responsible for the acquisition of data|approved the final manuscript|were responsible for the administrative, technical, or material support	were responsible for the acquisition of data	Performed the experiments	Investigation	YES
6206308	30374743	LW	2	were responsible for the acquisition of data|approved the final manuscript|were responsible for the administrative, technical, or material support	approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6206308	30374743	LW	2	were responsible for the acquisition of data|approved the final manuscript|were responsible for the administrative, technical, or material support	were responsible for the administrative, technical, or material support	Performed the experiments	Investigation|Project administration	YES
6206308	30374743	ME	2	were responsible for the conception and design and analysis and interpretation of data|were responsible for the acquisition of data|were responsible for the writing, review, and/or revision of the manuscript|approved the final manuscript|were responsible for the study supervision	were responsible for the conception and design and analysis and interpretation of data	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
6206308	30374743	ME	2	were responsible for the conception and design and analysis and interpretation of data|were responsible for the acquisition of data|were responsible for the writing, review, and/or revision of the manuscript|approved the final manuscript|were responsible for the study supervision	were responsible for the acquisition of data	Performed the experiments	Investigation	YES
6206308	30374743	ME	2	were responsible for the conception and design and analysis and interpretation of data|were responsible for the acquisition of data|were responsible for the writing, review, and/or revision of the manuscript|approved the final manuscript|were responsible for the study supervision	were responsible for the writing, review, and/or revision of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6206308	30374743	ME	2	were responsible for the conception and design and analysis and interpretation of data|were responsible for the acquisition of data|were responsible for the writing, review, and/or revision of the manuscript|approved the final manuscript|were responsible for the study supervision	approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6206308	30374743	ME	2	were responsible for the conception and design and analysis and interpretation of data|were responsible for the acquisition of data|were responsible for the writing, review, and/or revision of the manuscript|approved the final manuscript|were responsible for the study supervision	were responsible for the study supervision	-	Supervision	YES
6206308	30374743	MR	2	were responsible for the writing, review, and/or revision of the manuscript|approved the final manuscript	were responsible for the writing, review, and/or revision of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6206308	30374743	MR	2	were responsible for the writing, review, and/or revision of the manuscript|approved the final manuscript	approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6206308	30374743	RER	2	approved the final manuscript	approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6206308	30374743	RS	2	approved the final manuscript|were responsible for the administrative, technical, or material support	approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6206308	30374743	RS	2	approved the final manuscript|were responsible for the administrative, technical, or material support	were responsible for the administrative, technical, or material support	Performed the experiments	Investigation|Project administration	YES
6206308	30374743	SEA	2	were responsible for the acquisition of data|approved the final manuscript	were responsible for the acquisition of data	Performed the experiments	Investigation	YES
6206308	30374743	SEA	2	were responsible for the acquisition of data|approved the final manuscript	approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6206308	30374743	WPF	2	were responsible for the writing, review, and/or revision of the manuscript|approved the final manuscript	were responsible for the writing, review, and/or revision of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6206308	30374743	WPF	2	were responsible for the writing, review, and/or revision of the manuscript|approved the final manuscript	approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
1905940	17622355	AP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1905940	17622355	AP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1905940	17622355	AP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1905940	17622355	AP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1905940	17622355	AP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1905940	17622355	AS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1905940	17622355	AS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1905940	17622355	AS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1905940	17622355	AS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1905940	17622355	BH	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1905940	17622355	ES	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1905940	17622355	ES	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1905940	17622355	ES	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1905940	17622355	ES	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1905940	17622355	ES	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1905940	17622355	GN	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1905940	17622355	HA	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1905940	17622355	LL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1905940	17622355	MS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1905940	17622355	MS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1905940	17622355	MT	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1905940	17622355	PJ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1905940	17622355	PJ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1905940	17622355	PJ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1905940	17622355	TW	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1905940	17622355	TW	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5622428	28962550	ASP	PLoS5	Analyzed the data|Advised on the statistical analyses	Analyzed the data	Analyzed the data	Formal analysis	YES
5622428	28962550	ASP	PLoS5	Analyzed the data|Advised on the statistical analyses	Advised on the statistical analyses	Analyzed the data	Formal analysis	YES
5622428	28962550	AU	PLoS5	Performed the experiments|Analyzed the data|Immunohistochemistry	Performed the experiments	Performed the experiments	Investigation	YES
5622428	28962550	AU	PLoS5	Performed the experiments|Analyzed the data|Immunohistochemistry	Analyzed the data	Analyzed the data	Formal analysis	YES
5622428	28962550	AU	PLoS5	Performed the experiments|Analyzed the data|Immunohistochemistry	Immunohistochemistry	Performed the experiments	Investigation	YES
5622428	28962550	CLJC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5622428	28962550	CLJC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
5622428	28962550	CLJC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5622428	28962550	KT	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
5622428	28962550	KT	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5622428	28962550	LC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5622428	28962550	LC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
5622428	28962550	LC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5622428	28962550	SD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the manuscript|Network analysis|Performed experiments on cell lines	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5622428	28962550	SD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the manuscript|Network analysis|Performed experiments on cell lines	Performed the experiments	Performed the experiments	Investigation	YES
5622428	28962550	SD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the manuscript|Network analysis|Performed experiments on cell lines	Analyzed the data	Analyzed the data	Formal analysis	YES
5622428	28962550	SD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the manuscript|Network analysis|Performed experiments on cell lines	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5622428	28962550	SD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the manuscript|Network analysis|Performed experiments on cell lines	Network analysis	Analyzed the data	Formal analysis	YES
5622428	28962550	SD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the manuscript|Network analysis|Performed experiments on cell lines	Performed experiments on cell lines	Performed the experiments	Investigation	YES
5733015	29312391	C-YM	2	revised this article	revised this article	Wrote the paper	Writing - Review & Editing	YES
5733015	29312391	JY	2	revised this article	revised this article	Wrote the paper	Writing - Review & Editing	YES
5733015	29312391	R-LM	2	wrote the original draft of article	wrote the original draft of article	Wrote the paper	Writing - Original Draft	YES
5733015	29312391	X-XZ	2	wrote the original draft of article	wrote the original draft of article	Wrote the paper	Writing - Original Draft	YES
5733015	29312391	Y-XQ	2	conceived the ideas and contributed to substantial revisions	conceived the ideas and contributed to substantial revisions	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5733015	29312391	YL	2	conceived the ideas and contributed to substantial revisions	conceived the ideas and contributed to substantial revisions	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5733015	29312391	ZL	2	revised this article	revised this article	Wrote the paper	Writing - Review & Editing	YES
5733015	29312391	all authors	2	read and approved the final version of the manuscript	read and approved the final version of the manuscript	-	-	NO
4609764	26509145	Kristi S. Kelley	2	is the coauthor	is the coauthor	-	-	NO
4414549	25922939	CG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4414549	25922939	EM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414549	25922939	EM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414549	25922939	EM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414549	25922939	FA	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414549	25922939	GAD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414549	25922939	GAD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414549	25922939	GAD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414549	25922939	GAD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414549	25922939	ND	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4414549	25922939	SF	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414549	25922939	SF	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5025407	27637947	AB	2	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5025407	27637947	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5025407	27637947	JLR	2	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5025407	27637947	NK	2	designed the experiments|performed experiments|drafted the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5025407	27637947	NK	2	designed the experiments|performed experiments|drafted the manuscript	performed experiments	Performed the experiments	Investigation	YES
5025407	27637947	NK	2	designed the experiments|performed experiments|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5025407	27637947	RWS	2	designed the experiments|drafted the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5025407	27637947	RWS	2	designed the experiments|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5025407	27637947	UT	2	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5025407	27637947	UY	2	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
1905941	17622356	BV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1905941	17622356	BV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1905941	17622356	BV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1905941	17622356	BV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1905941	17622356	BV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1905941	17622356	LH	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6219999	30402779	JZ	2	made substantial contributions to the conception and design of the work, experimental performance, data processing, analysis and interpretation, and manuscript write up|provided final approval of the version submitted for publication and has agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	made substantial contributions to the conception and design of the work, experimental performance, data processing, analysis and interpretation, and manuscript write up	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Data curation|Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
6219999	30402779	JZ	2	made substantial contributions to the conception and design of the work, experimental performance, data processing, analysis and interpretation, and manuscript write up|provided final approval of the version submitted for publication and has agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	provided final approval of the version submitted for publication and has agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	-	-	NO
6219999	30402779	MVK	2	made substantial contributions to the conception and design of the work, clinical image reviews, guidelines, and manuscript write up|provided final approval of the version submitted for publication and has agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	made substantial contributions to the conception and design of the work, clinical image reviews, guidelines, and manuscript write up	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Visualization|Writing - Original Draft|Writing - Review & Editing	YES
6219999	30402779	MVK	2	made substantial contributions to the conception and design of the work, clinical image reviews, guidelines, and manuscript write up|provided final approval of the version submitted for publication and has agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	provided final approval of the version submitted for publication and has agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	-	-	NO
6219999	30402779	PM	2	made substantial contribution to the conception and design of the clinical trial and the lead on the investigational study from the side of the manufacturer|contributed to the review and editing of the manuscript	made substantial contribution to the conception and design of the clinical trial and the lead on the investigational study from the side of the manufacturer	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
6219999	30402779	PM	2	made substantial contribution to the conception and design of the clinical trial and the lead on the investigational study from the side of the manufacturer|contributed to the review and editing of the manuscript	contributed to the review and editing of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4414550	25923725	CB	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414550	25923725	CB	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414550	25923725	CPHM	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414550	25923725	CPHM	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414550	25923725	DB	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414550	25923725	DB	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414550	25923725	ET	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414550	25923725	ET	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414550	25923725	FAMT	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414550	25923725	IF	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414550	25923725	IF	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414550	25923725	JV	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414550	25923725	JV	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414550	25923725	MG	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414550	25923725	MG	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414550	25923725	MK	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414550	25923725	MK	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414550	25923725	SO	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414550	25923725	SO	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414550	25923725	SO	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414550	25923725	TAN	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414550	25923725	TAN	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3962552	24665435	AB	2	were responsible for collecting, compiling and analyzing the nutritional data and producing the manuscript	were responsible for collecting, compiling and analyzing the nutritional data and producing the manuscript	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3962552	24665435	BRL	2	designed the study, analyzed the data and wrote the first draft of the manuscript|were responsible for collecting, compiling and analyzing the nutritional data and producing the manuscript	designed the study, analyzed the data and wrote the first draft of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3962552	24665435	BRL	2	designed the study, analyzed the data and wrote the first draft of the manuscript|were responsible for collecting, compiling and analyzing the nutritional data and producing the manuscript	were responsible for collecting, compiling and analyzing the nutritional data and producing the manuscript	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3962552	24665435	JSS	2	participated in data interpretation and writing	participated in data interpretation and writing	Analyzed the data|Wrote the paper	Formal analysis	YES
5625832	28969601	FX	2	performed the experiment preparations	performed the experiment preparations	Performed the experiments	Investigation	YES
5625832	28969601	HL	2	carried out the analysis of data and revised the manuscript critically for important intellectual content	carried out the analysis of data and revised the manuscript critically for important intellectual content	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
5625832	28969601	LFZ	2	conceived of the study, participated in its design and coordination and drafted the manuscript	conceived of the study, participated in its design and coordination and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
5625832	28969601	PJ	2	conducted qrt pcr validation	conducted qrt pcr validation	Performed the experiments	Investigation|Validation	YES
5625832	28969601	WF	2	participated in the design and coordination and helped to draft the manuscript and provided the fund	participated in the design and coordination and helped to draft the manuscript and provided the fund	Conceived and designed the experiments|Wrote the paper	Funding acquisition|Project administration|Writing - Original Draft	YES
5625832	28969601	WZY	2	carried out the analysis of data and revised the manuscript critically for important intellectual content	carried out the analysis of data and revised the manuscript critically for important intellectual content	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
5625832	28969601	YH	2	conducted qrt pcr validation	conducted qrt pcr validation	Performed the experiments	Investigation|Validation	YES
5625832	28969601	ZGM	2	performed the experiment preparations	performed the experiment preparations	Performed the experiments	Investigation	YES
5625832	28969601	ZTT	2	conducted qrt pcr validation	conducted qrt pcr validation	Performed the experiments	Investigation|Validation	YES
5625832	28969601	ZYL	2	conceived of the study, participated in its design and coordination and drafted the manuscript|participated in the design and coordination and helped to draft the manuscript and provided the fund	conceived of the study, participated in its design and coordination and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
5625832	28969601	ZYL	2	conceived of the study, participated in its design and coordination and drafted the manuscript|participated in the design and coordination and helped to draft the manuscript and provided the fund	participated in the design and coordination and helped to draft the manuscript and provided the fund	Conceived and designed the experiments|Wrote the paper	Funding acquisition|Project administration|Writing - Original Draft	YES
5733034	29312368	All authors	2	contributed to the drafting/writing and interpretation of the work, and approve and are accountable for the final version of the manuscript	contributed to the drafting/writing and interpretation of the work, and approve and are accountable for the final version of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5733034	29312368	LH	2	did the statistics	did the statistics	Analyzed the data	Formal analysis	YES
5733034	29312368	MG	2	supervised and interpreted the fatty acid analysis	supervised and interpreted the fatty acid analysis	Analyzed the data	Formal analysis|Supervision	YES
5733034	29312368	RR	2	designed experimentation	designed experimentation	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5733034	29312368	X-DW	2	did the cytology	did the cytology	Performed the experiments	Investigation	YES
5733034	29312368	YS	2	designed experimentation|did the majority of experiments	designed experimentation	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5733034	29312368	YS	2	designed experimentation|did the majority of experiments	did the majority of experiments	Performed the experiments	Investigation	YES
1905942	17637843	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1905942	17637843	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1905942	17637843	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1905942	17637843	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1905942	17637843	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5025419	27637946	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5025419	27637946	LLM	2	conceived this study and constructed the bioreactors	conceived this study and constructed the bioreactors	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5025419	27637946	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5025419	27637946	WLD	2	contributed to analyze the data as well as results and wrote the manuscript	contributed to analyze the data as well as results and wrote the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
5025419	27637946	YL	2	conceived this study and constructed the bioreactors	conceived this study and constructed the bioreactors	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5025419	27637946	ZPL	2	conceived this study and constructed the bioreactors|supervised all the experiments and revised the manuscript	conceived this study and constructed the bioreactors	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5025419	27637946	ZPL	2	conceived this study and constructed the bioreactors|supervised all the experiments and revised the manuscript	supervised all the experiments and revised the manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
4414551	25923470	AM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4414551	25923470	JPT	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4414551	25923470	KK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414551	25923470	KK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4414551	25923470	KK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4414551	25923470	MTR	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414551	25923470	MTR	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414551	25923470	MTR	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414551	25923470	MW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414551	25923470	MW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414551	25923470	MW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414551	25923470	MW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414551	25923470	SH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4414551	25923470	TF	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4414551	25923470	TF	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4414551	25923470	TJR	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414551	25923470	TJR	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414551	25923470	TJR	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414551	25923470	TK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414551	25923470	TK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414551	25923470	TK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6226405	30414009	CS	2	helped with the literature search and acquisition and interpretation of the data	helped with the literature search and acquisition and interpretation of the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6226405	30414009	DH	2	participated in the study design and coordination and helped draft the manuscript	participated in the study design and coordination and helped draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft	YES
6226405	30414009	FH	2	revised the manuscript critically for important intellectual content and made substantial contributions to the data analysis	revised the manuscript critically for important intellectual content and made substantial contributions to the data analysis	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
6226405	30414009	IE	2	performed the literature search, collected and interpreted the data, and drafted the manuscript	performed the literature search, collected and interpreted the data, and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6226405	30414009	JG	2	participated in the study design and coordination and helped draft the manuscript	participated in the study design and coordination and helped draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft	YES
6226405	30414009	JH	2	revised the manuscript critically for important intellectual content and made substantial contributions to the data analysis	revised the manuscript critically for important intellectual content and made substantial contributions to the data analysis	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
6226405	30414009	KM	2	helped with the literature search and acquisition and interpretation of the data	helped with the literature search and acquisition and interpretation of the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6226405	30414009	KU	2	participated in the study design, collected the data, and edited the manuscript	participated in the study design, collected the data, and edited the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
6226405	30414009	ME	2	participated in the study design, collected the data, and edited the manuscript	participated in the study design, collected the data, and edited the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
6226405	30414009	NV	2	performed the literature search, collected and interpreted the data, and drafted the manuscript	performed the literature search, collected and interpreted the data, and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6226405	30414009	PW	2	helped with the literature search and acquisition and interpretation of the data	helped with the literature search and acquisition and interpretation of the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6226405	30414009	SB	2	helped with the literature search and acquisition and interpretation of the data	helped with the literature search and acquisition and interpretation of the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5733045	29312361	HR	2	coordinated, supervised and designed this study|wrote the manuscript and all the authors have commented, edited and approved the final manuscript	coordinated, supervised and designed this study	Conceived and designed the experiments	Methodology|Project administration|Supervision	YES
5733045	29312361	HR	2	coordinated, supervised and designed this study|wrote the manuscript and all the authors have commented, edited and approved the final manuscript	wrote the manuscript and all the authors have commented, edited and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5733045	29312361	RD	2	provided the dydh population and illumina snp data	provided the dydh population and illumina snp data	Contributed reagents/materials/analysis tools	Resources	YES
5629547	28984197	JW	2	joined the part work of data analysis	joined the part work of data analysis	Analyzed the data	Formal analysis	YES
5629547	28984197	PH	2	joined the part work of data analysis	joined the part work of data analysis	Analyzed the data	Formal analysis	YES
5629547	28984197	TX	2	implemented the study, performed data analysis and wrote the manuscript	implemented the study, performed data analysis and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5629547	28984197	XS	2	conceived the study and revised the manuscript	conceived the study and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5629547	28984197	ZZ	2	conceived the study and revised the manuscript	conceived the study and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
3984405	24765616	FS	2	conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5693824	28933041	MN	2	took part of the postoperative observation and helped to draft the manuscript	took part of the postoperative observation and helped to draft the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
1905943	17622339	AN	PLoS5	Contributed to project planning|Contributed data|Wrote parts of the paper	Contributed to project planning	Conceived and designed the experiments	Methodology	YES
1905943	17622339	AN	PLoS5	Contributed to project planning|Contributed data|Wrote parts of the paper	Contributed data	Contributed reagents/materials/analysis tools	Resources	YES
1905943	17622339	AN	PLoS5	Contributed to project planning|Contributed data|Wrote parts of the paper	Wrote parts of the paper	Wrote the paper	Writing - Original Draft	YES
1905943	17622339	AP	PLoS5	Provided data layers|Wrote parts of the paper	Provided data layers	Contributed reagents/materials/analysis tools	Resources	YES
1905943	17622339	AP	PLoS5	Provided data layers|Wrote parts of the paper	Wrote parts of the paper	Wrote the paper	Writing - Original Draft	YES
1905943	17622339	EW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote large parts of the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1905943	17622339	EW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote large parts of the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1905943	17622339	EW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote large parts of the paper	Wrote large parts of the paper	Wrote the paper	Writing - Original Draft	YES
1905943	17622339	RG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote large parts of the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1905943	17622339	RG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote large parts of the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1905943	17622339	RG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote large parts of the paper	Wrote large parts of the paper	Wrote the paper	Writing - Original Draft	YES
1905943	17622339	RH	PLoS5	Provided data layers|Wrote parts of the paper	Provided data layers	Contributed reagents/materials/analysis tools	Resources	YES
1905943	17622339	RH	PLoS5	Provided data layers|Wrote parts of the paper	Wrote parts of the paper	Wrote the paper	Writing - Original Draft	YES
1905943	17622339	SP	PLoS5	Contributed to project planning|Contributed to paper writing	Contributed to project planning	Conceived and designed the experiments	Methodology	YES
1905943	17622339	SP	PLoS5	Contributed to project planning|Contributed to paper writing	Contributed to paper writing	Wrote the paper	-	YES
4414552	25923333	JX	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414552	25923333	NW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4414552	25923333	PG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414552	25923333	PG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414552	25923333	PG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414552	25923333	PG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414552	25923333	PG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414552	25923333	YZ	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414552	25923333	ZDL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4414552	25923333	ZDL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4414552	25923333	ZDL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
6238014	30443684	AL	2	participated in the planning and design of the study|wrote the substantial parts of the draft of the manuscript|was responsible for the spect protocol|prepared and analyzed the spect data	participated in the planning and design of the study	Conceived and designed the experiments	Methodology	YES
6238014	30443684	AL	2	participated in the planning and design of the study|wrote the substantial parts of the draft of the manuscript|was responsible for the spect protocol|prepared and analyzed the spect data	wrote the substantial parts of the draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
6238014	30443684	AL	2	participated in the planning and design of the study|wrote the substantial parts of the draft of the manuscript|was responsible for the spect protocol|prepared and analyzed the spect data	was responsible for the spect protocol	Conceived and designed the experiments	Methodology	YES
6238014	30443684	AL	2	participated in the planning and design of the study|wrote the substantial parts of the draft of the manuscript|was responsible for the spect protocol|prepared and analyzed the spect data	prepared and analyzed the spect data	Analyzed the data	Formal analysis	YES
6238014	30443684	AV	2	participated in the planning and design of the study|was responsible for the development of the pet tracer	participated in the planning and design of the study	Conceived and designed the experiments	Methodology	YES
6238014	30443684	AV	2	participated in the planning and design of the study|was responsible for the development of the pet tracer	was responsible for the development of the pet tracer	-	-	NO
6238014	30443684	DB	2	performed the clinical examinations of the patients and healthy volunteers	performed the clinical examinations of the patients and healthy volunteers	Performed the experiments	Investigation	YES
6238014	30443684	JA	2	participated in the planning and design of the study|wrote the substantial parts of the draft of the manuscript	participated in the planning and design of the study	Conceived and designed the experiments	Methodology	YES
6238014	30443684	JA	2	participated in the planning and design of the study|wrote the substantial parts of the draft of the manuscript	wrote the substantial parts of the draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
6238014	30443684	JL	2	participated in the planning and design of the study|was responsible for the selection of the patients|performed the clinical examinations of the patients and healthy volunteers	participated in the planning and design of the study	Conceived and designed the experiments	Methodology	YES
6238014	30443684	JL	2	participated in the planning and design of the study|was responsible for the selection of the patients|performed the clinical examinations of the patients and healthy volunteers	was responsible for the selection of the patients	-	-	NO
6238014	30443684	JL	2	participated in the planning and design of the study|was responsible for the selection of the patients|performed the clinical examinations of the patients and healthy volunteers	performed the clinical examinations of the patients and healthy volunteers	Performed the experiments	Investigation	YES
6238014	30443684	KR	2	participated in the planning and design of the study	participated in the planning and design of the study	Conceived and designed the experiments	Methodology	YES
6238014	30443684	LE	2	performed the clinical examinations of the patients and healthy volunteers	performed the clinical examinations of the patients and healthy volunteers	Performed the experiments	Investigation	YES
6238014	30443684	LJ	2	wrote the substantial parts of the draft of the manuscript|was responsible for the preprocessing and segmentations and assisted in the analysis of the mri and pet data	wrote the substantial parts of the draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
6238014	30443684	LJ	2	wrote the substantial parts of the draft of the manuscript|was responsible for the preprocessing and segmentations and assisted in the analysis of the mri and pet data	was responsible for the preprocessing and segmentations and assisted in the analysis of the mri and pet data	Analyzed the data	Data curation|Formal analysis	YES
6238014	30443684	MJO	2	participated in the planning and design of the study|wrote the substantial parts of the draft of the manuscript|were responsible for the pet chemistry development and production of the pet tracer	participated in the planning and design of the study	Conceived and designed the experiments	Methodology	YES
6238014	30443684	MJO	2	participated in the planning and design of the study|wrote the substantial parts of the draft of the manuscript|were responsible for the pet chemistry development and production of the pet tracer	wrote the substantial parts of the draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
6238014	30443684	MJO	2	participated in the planning and design of the study|wrote the substantial parts of the draft of the manuscript|were responsible for the pet chemistry development and production of the pet tracer	were responsible for the pet chemistry development and production of the pet tracer	-	-	NO
6238014	30443684	MO	2	were responsible for the pet chemistry development and production of the pet tracer	were responsible for the pet chemistry development and production of the pet tracer	-	-	NO
6238014	30443684	PET	2	protocols and algorithms for delineation and performed the analysis of the pet data	protocols and algorithms for delineation and performed the analysis of the pet data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Methodology|Software	YES
6238014	30443684	SJM	2	was responsible for the initiation, design, and execution of the study|wrote the substantial parts of the draft of the manuscript|prepared and analyzed the spect data|participated in the segmentation of the mri data	was responsible for the initiation, design, and execution of the study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6238014	30443684	SJM	2	was responsible for the initiation, design, and execution of the study|wrote the substantial parts of the draft of the manuscript|prepared and analyzed the spect data|participated in the segmentation of the mri data	wrote the substantial parts of the draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
6238014	30443684	SJM	2	was responsible for the initiation, design, and execution of the study|wrote the substantial parts of the draft of the manuscript|prepared and analyzed the spect data|participated in the segmentation of the mri data	prepared and analyzed the spect data	Analyzed the data	Formal analysis	YES
6238014	30443684	SJM	2	was responsible for the initiation, design, and execution of the study|wrote the substantial parts of the draft of the manuscript|prepared and analyzed the spect data|participated in the segmentation of the mri data	participated in the segmentation of the mri data	-	-	NO
6238014	30443684	SaB	2	participated in the planning and design of the study|participated in the segmentation of the mri data|performed the clinical examinations of the patients and healthy volunteers	participated in the planning and design of the study	Conceived and designed the experiments	Methodology	YES
6238014	30443684	SaB	2	participated in the planning and design of the study|participated in the segmentation of the mri data|performed the clinical examinations of the patients and healthy volunteers	participated in the segmentation of the mri data	-	-	NO
6238014	30443684	SaB	2	participated in the planning and design of the study|participated in the segmentation of the mri data|performed the clinical examinations of the patients and healthy volunteers	performed the clinical examinations of the patients and healthy volunteers	Performed the experiments	Investigation	YES
5025423	27637945	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5025423	27637945	BLAST	2	analysis, in silico analyses, antifungal susceptibility tests, investigation of the antifungal effect manifestation, thermal stability investigation, interpretation of these data	analysis, in silico analyses, antifungal susceptibility tests, investigation of the antifungal effect manifestation, thermal stability investigation, interpretation of these data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5025423	27637945	ECD	2	spectroscopy, interpretation of ecd data	spectroscopy, interpretation of ecd data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5025423	27637945	MS	2	analyses, interpretation of ms data	analyses, interpretation of ms data	Analyzed the data	Formal analysis	YES
5025423	27637945	NFAP	2	and nfap2	and nfap2	-	-	NO
5629553	28984209	All authors	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5629553	28984209	EYC	2	conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5629553	28984209	LJW	2	conceived the study|designed the study and performed data analysis|interpreted the data	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5629553	28984209	LJW	2	conceived the study|designed the study and performed data analysis|interpreted the data	designed the study and performed data analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5629553	28984209	LJW	2	conceived the study|designed the study and performed data analysis|interpreted the data	interpreted the data	Analyzed the data	Formal analysis	YES
5629553	28984209	THH	2	conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5629553	28984209	YC	2	conceived the study|interpreted the data	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5629553	28984209	YC	2	conceived the study|interpreted the data	interpreted the data	Analyzed the data	Formal analysis	YES
5629553	28984209	YCC	2	conceived the study|designed the study and performed data analysis|interpreted the data	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5629553	28984209	YCC	2	conceived the study|designed the study and performed data analysis|interpreted the data	designed the study and performed data analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5629553	28984209	YCC	2	conceived the study|designed the study and performed data analysis|interpreted the data	interpreted the data	Analyzed the data	Formal analysis	YES
5733048	29312369	GC-TOF	2	data analysis	data analysis	Analyzed the data	Formal analysis	YES
1905944	17622353	CP	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1905944	17622353	ED	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1905944	17622353	ED	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1905944	17622353	ED	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1905944	17622353	GM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1905944	17622353	HL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1905944	17622353	JM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1905944	17622353	JM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1905944	17622353	JM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1905944	17622353	OD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1905944	17622353	OD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1905944	17622353	OD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1905944	17622353	OD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1905944	17622353	PS	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1905944	17622353	VP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4414554	25923243	AYK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414554	25923243	AYK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414554	25923243	AYK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414554	25923243	BRW	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414554	25923243	BRW	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414554	25923243	ESB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414554	25923243	ESB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414554	25923243	ESB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414554	25923243	JBW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414554	25923243	JBW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414554	25923243	JBW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414554	25923243	MES	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414554	25923243	MES	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414554	25923243	MES	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414554	25923243	PES	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414554	25923243	PES	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414554	25923243	RT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414554	25923243	RT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414554	25923243	RT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414554	25923243	RTC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414554	25923243	RTC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414554	25923243	RTC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6238015	30443801	AD	2	participated to the patient care and dataset collection	participated to the patient care and dataset collection	Performed the experiments	Investigation	YES
6238015	30443801	BF	2	participated to the dataset collection	participated to the dataset collection	Performed the experiments	Investigation	YES
6238015	30443801	DB	2	participated in the design of the study and developed the parapet methodology	participated in the design of the study and developed the parapet methodology	Conceived and designed the experiments|Performed the experiments	Methodology	YES
6238015	30443801	DT	2	participated in the design and the promotion of the study	participated in the design and the promotion of the study	Conceived and designed the experiments	Methodology	YES
6238015	30443801	EC	2	participated in the design of the study, the patient care and developed the parapet methodology	participated in the design of the study, the patient care and developed the parapet methodology	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6238015	30443801	IG	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
6238015	30443801	JL	2	performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
6238015	30443801	LP	2	helped in the design and coordination of the study, and participated to the patient inclusion in the clinical trial	helped in the design and coordination of the study, and participated to the patient inclusion in the clinical trial	Conceived and designed the experiments	Methodology|Project administration	YES
6238015	30443801	PG	2	participated to the patient care and dataset collection	participated to the patient care and dataset collection	Performed the experiments	Investigation	YES
6238015	30443801	PV	2	participated in the design and the promotion of the study	participated in the design and the promotion of the study	Conceived and designed the experiments	Methodology	YES
6238015	30443801	SD	2	participated to the patient inclusion in the clinical trial and the patient care	participated to the patient inclusion in the clinical trial and the patient care	Performed the experiments	Investigation	YES
6238015	30443801	SH	2	conceived the study, participated in its design and coordination, drafted the manuscript and performed the statistical analysis	conceived the study, participated in its design and coordination, drafted the manuscript and performed the statistical analysis	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Project administration|Writing - Original Draft	YES
6238015	30443801	ST	2	helped in the design of the study and participated to the patient inclusion in the clinical trial	helped in the design of the study and participated to the patient inclusion in the clinical trial	Conceived and designed the experiments	Methodology	YES
5733070	29312381	AG	2	supervised the research	supervised the research	-	Supervision	YES
5733070	29312381	All authors	2	read and approved the final copy of the manuscript	read and approved the final copy of the manuscript	-	-	NO
5733070	29312381	HD	2	supervised the research	supervised the research	-	Supervision	YES
5733070	29312381	MH	2	designed the research|provided research materials, analysis tools and worldwide data|supervised the research	designed the research	Conceived and designed the experiments	Methodology	YES
5733070	29312381	MH	2	designed the research|provided research materials, analysis tools and worldwide data|supervised the research	provided research materials, analysis tools and worldwide data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5733070	29312381	MH	2	designed the research|provided research materials, analysis tools and worldwide data|supervised the research	supervised the research	-	Supervision	YES
5733070	29312381	RJ	2	designed the research|performed the research, analyzed the data and drafted the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
5733070	29312381	RJ	2	designed the research|performed the research, analyzed the data and drafted the manuscript	performed the research, analyzed the data and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5025425	27637948	All	2	this work was carried out under the|materials used for the manuscript has been dully acknowledged	this work was carried out under the	Performed the experiments	Investigation	YES
5025425	27637948	All	2	this work was carried out under the|materials used for the manuscript has been dully acknowledged	materials used for the manuscript has been dully acknowledged	-	-	NO
5025425	27637948	All authors	2	read and approved the final manuscript|in this manuscript, here honestly declare that this manuscript is their own original work and has not been submitted by them or any other body else to another journal to fulfill a similar purpose	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5025425	27637948	All authors	2	read and approved the final manuscript|in this manuscript, here honestly declare that this manuscript is their own original work and has not been submitted by them or any other body else to another journal to fulfill a similar purpose	in this manuscript, here honestly declare that this manuscript is their own original work and has not been submitted by them or any other body else to another journal to fulfill a similar purpose	-	-	NO
5025425	27637948	CP	2	supervised the ll this work was carried out under the|also helped in editing the manuscript	supervised the ll this work was carried out under the	Performed the experiments	Investigation|Supervision	YES
5025425	27637948	CP	2	supervised the ll this work was carried out under the|also helped in editing the manuscript	also helped in editing the manuscript	Wrote the paper	Writing - Review & Editing	YES
5025425	27637948	DA	2	supervised the ll this work was carried out under the|also helped in editing the manuscript	supervised the ll this work was carried out under the	Performed the experiments	Investigation|Supervision	YES
5025425	27637948	DA	2	supervised the ll this work was carried out under the|also helped in editing the manuscript	also helped in editing the manuscript	Wrote the paper	Writing - Review & Editing	YES
5025425	27637948	MG	2	helped in molecular analysis|also helped in editing the manuscript	helped in molecular analysis	Performed the experiments	Investigation	YES
5025425	27637948	MG	2	helped in molecular analysis|also helped in editing the manuscript	also helped in editing the manuscript	Wrote the paper	Writing - Review & Editing	YES
5025425	27637948	NK	2	supervised the ll this work was carried out under the|also helped in editing the manuscript	supervised the ll this work was carried out under the	Performed the experiments	Investigation|Supervision	YES
5025425	27637948	NK	2	supervised the ll this work was carried out under the|also helped in editing the manuscript	also helped in editing the manuscript	Wrote the paper	Writing - Review & Editing	YES
5025425	27637948	TMJ	2	performed the experiments as part of his doctoral work	performed the experiments as part of his doctoral work	Performed the experiments	Investigation	YES
5025425	27637948	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5629558	28984201	AVI	2	conceptualized this work|downloaded data from databases, managed and analyzed clinical data|also performed survival prediction, statistical and gene network analyses	conceptualized this work	Conceived and designed the experiments	Conceptualization	YES
5629558	28984201	AVI	2	conceptualized this work|downloaded data from databases, managed and analyzed clinical data|also performed survival prediction, statistical and gene network analyses	downloaded data from databases, managed and analyzed clinical data	Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Formal analysis|Software	YES
5629558	28984201	AVI	2	conceptualized this work|downloaded data from databases, managed and analyzed clinical data|also performed survival prediction, statistical and gene network analyses	also performed survival prediction, statistical and gene network analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5629558	28984201	VAK	2	conceptualized this work|provided studys design, coordination of the study and wrote a final version of the manuscript|also performed survival prediction, statistical and gene network analyses	conceptualized this work	Conceived and designed the experiments	Conceptualization	YES
5629558	28984201	VAK	2	conceptualized this work|provided studys design, coordination of the study and wrote a final version of the manuscript|also performed survival prediction, statistical and gene network analyses	provided studys design, coordination of the study and wrote a final version of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft	YES
5629558	28984201	VAK	2	conceptualized this work|provided studys design, coordination of the study and wrote a final version of the manuscript|also performed survival prediction, statistical and gene network analyses	also performed survival prediction, statistical and gene network analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5629558	28984201	ZT	2	wrote the initial draft of the manuscript|performed microarray data analysis, including data quality control|also performed survival prediction, statistical and gene network analyses	wrote the initial draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
5629558	28984201	ZT	2	wrote the initial draft of the manuscript|performed microarray data analysis, including data quality control|also performed survival prediction, statistical and gene network analyses	performed microarray data analysis, including data quality control	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation|Validation	YES
5629558	28984201	ZT	2	wrote the initial draft of the manuscript|performed microarray data analysis, including data quality control|also performed survival prediction, statistical and gene network analyses	also performed survival prediction, statistical and gene network analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
1905945	17637836	AH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1905945	17637836	AH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1905945	17637836	AH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1905945	17637836	AH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1905945	17637836	AH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1905945	17637836	AJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1905945	17637836	AJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1905945	17637836	AJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1905945	17637836	AJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1905945	17637836	AJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1905945	17637836	ES	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1905945	17637836	ES	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1905945	17637836	HT	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1905945	17637836	HT	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1905945	17637836	JA	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1905945	17637836	JA	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1905945	17637836	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1905945	17637836	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1905945	17637836	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1905945	17637836	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1905945	17637836	KK	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1905945	17637836	LT	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1905945	17637836	LT	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1905945	17637836	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1905945	17637836	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1905945	17637836	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1905945	17637836	SC	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1905945	17637836	SC	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1905945	17637836	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1905945	17637836	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1905945	17637836	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1905945	17637836	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1905945	17637836	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414555	25923718	RC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414555	25923718	RC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414555	25923718	RC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414555	25923718	RC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414555	25923718	SPR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414555	25923718	SPR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414555	25923718	SPR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414555	25923718	SPR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414555	25923718	SPR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414555	25923718	ST	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414555	25923718	ST	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414555	25923718	ST	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4609771	26509151	Solmaz Abdolrahimzadeh	2	contributed equally	contributed equally	-	-	NO
4609771	26509151	Vito Fenicia	2	contributed equally	contributed equally	-	-	NO
6246760	30460579	AB	2	contributed to the study concepts and design|contributed to the data acquisition and quality control of the data|contributed to the data analyses and interpretation|contributed to the statistical analysis|contributed to the manuscript preparation|contributed to the manuscript review and editing	contributed to the study concepts and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6246760	30460579	AB	2	contributed to the study concepts and design|contributed to the data acquisition and quality control of the data|contributed to the data analyses and interpretation|contributed to the statistical analysis|contributed to the manuscript preparation|contributed to the manuscript review and editing	contributed to the data acquisition and quality control of the data	Performed the experiments	Data curation|Investigation|Validation	YES
6246760	30460579	AB	2	contributed to the study concepts and design|contributed to the data acquisition and quality control of the data|contributed to the data analyses and interpretation|contributed to the statistical analysis|contributed to the manuscript preparation|contributed to the manuscript review and editing	contributed to the data analyses and interpretation	Analyzed the data	Formal analysis	YES
6246760	30460579	AB	2	contributed to the study concepts and design|contributed to the data acquisition and quality control of the data|contributed to the data analyses and interpretation|contributed to the statistical analysis|contributed to the manuscript preparation|contributed to the manuscript review and editing	contributed to the statistical analysis	Analyzed the data	Formal analysis	YES
6246760	30460579	AB	2	contributed to the study concepts and design|contributed to the data acquisition and quality control of the data|contributed to the data analyses and interpretation|contributed to the statistical analysis|contributed to the manuscript preparation|contributed to the manuscript review and editing	contributed to the manuscript preparation	Wrote the paper	Writing - Original Draft	YES
6246760	30460579	AB	2	contributed to the study concepts and design|contributed to the data acquisition and quality control of the data|contributed to the data analyses and interpretation|contributed to the statistical analysis|contributed to the manuscript preparation|contributed to the manuscript review and editing	contributed to the manuscript review and editing	Wrote the paper	Writing - Review & Editing	YES
6246760	30460579	EH	2	contributed to the study concepts and design|contributed to the data acquisition and quality control of the data|contributed to the data analyses and interpretation|contributed to the statistical analysis|contributed to the manuscript preparation|contributed to the manuscript review and editing	contributed to the study concepts and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6246760	30460579	EH	2	contributed to the study concepts and design|contributed to the data acquisition and quality control of the data|contributed to the data analyses and interpretation|contributed to the statistical analysis|contributed to the manuscript preparation|contributed to the manuscript review and editing	contributed to the data acquisition and quality control of the data	Performed the experiments	Data curation|Investigation|Validation	YES
6246760	30460579	EH	2	contributed to the study concepts and design|contributed to the data acquisition and quality control of the data|contributed to the data analyses and interpretation|contributed to the statistical analysis|contributed to the manuscript preparation|contributed to the manuscript review and editing	contributed to the data analyses and interpretation	Analyzed the data	Formal analysis	YES
6246760	30460579	EH	2	contributed to the study concepts and design|contributed to the data acquisition and quality control of the data|contributed to the data analyses and interpretation|contributed to the statistical analysis|contributed to the manuscript preparation|contributed to the manuscript review and editing	contributed to the statistical analysis	Analyzed the data	Formal analysis	YES
6246760	30460579	EH	2	contributed to the study concepts and design|contributed to the data acquisition and quality control of the data|contributed to the data analyses and interpretation|contributed to the statistical analysis|contributed to the manuscript preparation|contributed to the manuscript review and editing	contributed to the manuscript preparation	Wrote the paper	Writing - Original Draft	YES
6246760	30460579	EH	2	contributed to the study concepts and design|contributed to the data acquisition and quality control of the data|contributed to the data analyses and interpretation|contributed to the statistical analysis|contributed to the manuscript preparation|contributed to the manuscript review and editing	contributed to the manuscript review and editing	Wrote the paper	Writing - Review & Editing	YES
6246760	30460579	EV	2	contributed to the study concepts and design|contributed to the data analyses and interpretation|contributed to the manuscript review and editing	contributed to the study concepts and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6246760	30460579	EV	2	contributed to the study concepts and design|contributed to the data analyses and interpretation|contributed to the manuscript review and editing	contributed to the data analyses and interpretation	Analyzed the data	Formal analysis	YES
6246760	30460579	EV	2	contributed to the study concepts and design|contributed to the data analyses and interpretation|contributed to the manuscript review and editing	contributed to the manuscript review and editing	Wrote the paper	Writing - Review & Editing	YES
6246760	30460579	GD	2	contributed to the data acquisition and quality control of the data|contributed to the data analyses and interpretation|contributed to the manuscript review and editing	contributed to the data acquisition and quality control of the data	Performed the experiments	Data curation|Investigation|Validation	YES
6246760	30460579	GD	2	contributed to the data acquisition and quality control of the data|contributed to the data analyses and interpretation|contributed to the manuscript review and editing	contributed to the data analyses and interpretation	Analyzed the data	Formal analysis	YES
6246760	30460579	GD	2	contributed to the data acquisition and quality control of the data|contributed to the data analyses and interpretation|contributed to the manuscript review and editing	contributed to the manuscript review and editing	Wrote the paper	Writing - Review & Editing	YES
6246760	30460579	GH	2	contributed to the study concepts and design|contributed to the data analyses and interpretation|contributed to the manuscript review and editing	contributed to the study concepts and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6246760	30460579	GH	2	contributed to the study concepts and design|contributed to the data analyses and interpretation|contributed to the manuscript review and editing	contributed to the data analyses and interpretation	Analyzed the data	Formal analysis	YES
6246760	30460579	GH	2	contributed to the study concepts and design|contributed to the data analyses and interpretation|contributed to the manuscript review and editing	contributed to the manuscript review and editing	Wrote the paper	Writing - Review & Editing	YES
6246760	30460579	MJ	2	contributed to the study concepts and design|contributed to the data acquisition and quality control of the data|contributed to the data analyses and interpretation|contributed to the statistical analysis|contributed to the manuscript preparation|contributed to the manuscript review and editing	contributed to the study concepts and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6246760	30460579	MJ	2	contributed to the study concepts and design|contributed to the data acquisition and quality control of the data|contributed to the data analyses and interpretation|contributed to the statistical analysis|contributed to the manuscript preparation|contributed to the manuscript review and editing	contributed to the data acquisition and quality control of the data	Performed the experiments	Data curation|Investigation|Validation	YES
6246760	30460579	MJ	2	contributed to the study concepts and design|contributed to the data acquisition and quality control of the data|contributed to the data analyses and interpretation|contributed to the statistical analysis|contributed to the manuscript preparation|contributed to the manuscript review and editing	contributed to the data analyses and interpretation	Analyzed the data	Formal analysis	YES
6246760	30460579	MJ	2	contributed to the study concepts and design|contributed to the data acquisition and quality control of the data|contributed to the data analyses and interpretation|contributed to the statistical analysis|contributed to the manuscript preparation|contributed to the manuscript review and editing	contributed to the statistical analysis	Analyzed the data	Formal analysis	YES
6246760	30460579	MJ	2	contributed to the study concepts and design|contributed to the data acquisition and quality control of the data|contributed to the data analyses and interpretation|contributed to the statistical analysis|contributed to the manuscript preparation|contributed to the manuscript review and editing	contributed to the manuscript preparation	Wrote the paper	Writing - Original Draft	YES
6246760	30460579	MJ	2	contributed to the study concepts and design|contributed to the data acquisition and quality control of the data|contributed to the data analyses and interpretation|contributed to the statistical analysis|contributed to the manuscript preparation|contributed to the manuscript review and editing	contributed to the manuscript review and editing	Wrote the paper	Writing - Review & Editing	YES
6246760	30460579	RB	2	contributed to the study concepts and design|contributed to the data acquisition and quality control of the data|contributed to the data analyses and interpretation|contributed to the statistical analysis|contributed to the manuscript preparation|contributed to the manuscript review and editing	contributed to the study concepts and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6246760	30460579	RB	2	contributed to the study concepts and design|contributed to the data acquisition and quality control of the data|contributed to the data analyses and interpretation|contributed to the statistical analysis|contributed to the manuscript preparation|contributed to the manuscript review and editing	contributed to the data acquisition and quality control of the data	Performed the experiments	Data curation|Investigation|Validation	YES
6246760	30460579	RB	2	contributed to the study concepts and design|contributed to the data acquisition and quality control of the data|contributed to the data analyses and interpretation|contributed to the statistical analysis|contributed to the manuscript preparation|contributed to the manuscript review and editing	contributed to the data analyses and interpretation	Analyzed the data	Formal analysis	YES
6246760	30460579	RB	2	contributed to the study concepts and design|contributed to the data acquisition and quality control of the data|contributed to the data analyses and interpretation|contributed to the statistical analysis|contributed to the manuscript preparation|contributed to the manuscript review and editing	contributed to the statistical analysis	Analyzed the data	Formal analysis	YES
6246760	30460579	RB	2	contributed to the study concepts and design|contributed to the data acquisition and quality control of the data|contributed to the data analyses and interpretation|contributed to the statistical analysis|contributed to the manuscript preparation|contributed to the manuscript review and editing	contributed to the manuscript preparation	Wrote the paper	Writing - Original Draft	YES
6246760	30460579	RB	2	contributed to the study concepts and design|contributed to the data acquisition and quality control of the data|contributed to the data analyses and interpretation|contributed to the statistical analysis|contributed to the manuscript preparation|contributed to the manuscript review and editing	contributed to the manuscript review and editing	Wrote the paper	Writing - Review & Editing	YES
6246760	30460579	WS	2	contributed to the study concepts and design|contributed to the data analyses and interpretation|contributed to the statistical analysis|contributed to the manuscript review and editing	contributed to the study concepts and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6246760	30460579	WS	2	contributed to the study concepts and design|contributed to the data analyses and interpretation|contributed to the statistical analysis|contributed to the manuscript review and editing	contributed to the data analyses and interpretation	Analyzed the data	Formal analysis	YES
6246760	30460579	WS	2	contributed to the study concepts and design|contributed to the data analyses and interpretation|contributed to the statistical analysis|contributed to the manuscript review and editing	contributed to the statistical analysis	Analyzed the data	Formal analysis	YES
6246760	30460579	WS	2	contributed to the study concepts and design|contributed to the data analyses and interpretation|contributed to the statistical analysis|contributed to the manuscript review and editing	contributed to the manuscript review and editing	Wrote the paper	Writing - Review & Editing	YES
5026979	27639854	All authors	2	contributed in the final approval|read and approved the final manuscript	contributed in the final approval	-	-	NO
5026979	27639854	All authors	2	contributed in the final approval|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5026979	27639854	CQ	2	contributed to the conception and design of the experiments	contributed to the conception and design of the experiments	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
5026979	27639854	GHZ	2	performed the experiments, analyzed the data and drafted the manuscript	performed the experiments, analyzed the data and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5026979	27639854	QK	2	contributed to the conception and design of the experiments|performed the experiments, analyzed the data and drafted the manuscript	contributed to the conception and design of the experiments	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
5026979	27639854	QK	2	contributed to the conception and design of the experiments|performed the experiments, analyzed the data and drafted the manuscript	performed the experiments, analyzed the data and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5026979	27639854	RHL	2	performed the experiments, analyzed the data and drafted the manuscript	performed the experiments, analyzed the data and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5026979	27639854	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5026979	27639854	YJC	2	contributed to the conception and design of the experiments	contributed to the conception and design of the experiments	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
5026979	27639854	YLC	2	contributed to the conception and design of the experiments	contributed to the conception and design of the experiments	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
5026979	27639854	YXM	2	contributed to the conception and design of the experiments|performed the experiments, analyzed the data and drafted the manuscript	contributed to the conception and design of the experiments	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
5026979	27639854	YXM	2	contributed to the conception and design of the experiments|performed the experiments, analyzed the data and drafted the manuscript	performed the experiments, analyzed the data and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5629559	28984206	JR	2	conceived of the study, participated in its design and helped to draft the manuscript	conceived of the study, participated in its design and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
5629559	28984206	LL	2	involved in the application design and deployed the web service	involved in the application design and deployed the web service	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
5629559	28984206	ZG	2	proposed the study, designed the application, accomplished the data analysis, and, drafted the manuscript	proposed the study, designed the application, accomplished the data analysis, and, drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
1906859	17637838	JN	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1906859	17637838	JPN	PLoS5	Interpreted the data	Interpreted the data	Analyzed the data	Formal analysis	YES
1906859	17637838	PT	PLoS5	Performed sequencing of human samples	Performed sequencing of human samples	Performed the experiments	Investigation	YES
1906859	17637838	RA	PLoS5	Wrote the paper|Interpreted the data|Developed the elimination method|Analyzed all probe level data	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1906859	17637838	RA	PLoS5	Wrote the paper|Interpreted the data|Developed the elimination method|Analyzed all probe level data	Interpreted the data	Analyzed the data	Formal analysis	YES
1906859	17637838	RA	PLoS5	Wrote the paper|Interpreted the data|Developed the elimination method|Analyzed all probe level data	Developed the elimination method	Performed the experiments	Methodology	YES
1906859	17637838	RA	PLoS5	Wrote the paper|Interpreted the data|Developed the elimination method|Analyzed all probe level data	Analyzed all probe level data	Analyzed the data	Formal analysis	YES
1906859	17637838	RB	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1906859	17637838	RCJ	PLoS5	Initiated and supervised the study|Conceived the study of individual probes|Interpreted the data|Developed the elimination method	Initiated and supervised the study	Conceived and designed the experiments	Conceptualization|Supervision	YES
1906859	17637838	RCJ	PLoS5	Initiated and supervised the study|Conceived the study of individual probes|Interpreted the data|Developed the elimination method	Conceived the study of individual probes	Conceived and designed the experiments	Conceptualization	YES
1906859	17637838	RCJ	PLoS5	Initiated and supervised the study|Conceived the study of individual probes|Interpreted the data|Developed the elimination method	Interpreted the data	Analyzed the data	Formal analysis	YES
1906859	17637838	RCJ	PLoS5	Initiated and supervised the study|Conceived the study of individual probes|Interpreted the data|Developed the elimination method	Developed the elimination method	Performed the experiments	Methodology	YES
1906859	17637838	RJ	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1906859	17637838	RJ	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414556	25923203	DK	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414556	25923203	DK	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414556	25923203	DK	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414556	25923203	MJB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414556	25923203	MJB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414556	25923203	MJB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414556	25923203	SAV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414556	25923203	SAV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414556	25923203	SAV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414556	25923203	SAV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414556	25923203	SAV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5733080	29312375	Y-BT	PLoS52	designed the experiments|wrote the paper	designed the experiments	Conceived and designed the experiments	Methodology	YES
5733080	29312375	Y-BT	PLoS52	designed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5733080	29312375	Y-XH	PLoS52	designed the experiments|performed the experiments and analyzed the data|wrote the paper	designed the experiments	Conceived and designed the experiments	Methodology	YES
5733080	29312375	Y-XH	PLoS52	designed the experiments|performed the experiments and analyzed the data|wrote the paper	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5733080	29312375	Y-XH	PLoS52	designed the experiments|performed the experiments and analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5733080	29312375	Z-FX	PLoS52	designed the experiments|wrote the paper	designed the experiments	Conceived and designed the experiments	Methodology	YES
5733080	29312375	Z-FX	PLoS52	designed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6265355	30498919	All authors	2	interpreted the results, critically revised the article, and approved of the final version for publication	interpreted the results, critically revised the article, and approved of the final version for publication	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
6265355	30498919	GJM	2	performed the kinetic modeling	performed the kinetic modeling	Performed the experiments	Investigation|Methodology	YES
6265355	30498919	LF	2	supervised the study	supervised the study	-	Supervision	YES
6265355	30498919	PPS	2	conceived of the study and designed the study|carried out the image analysis|performed the kinetic modeling|carried out the statistical analyses|drafted the article	conceived of the study and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6265355	30498919	PPS	2	conceived of the study and designed the study|carried out the image analysis|performed the kinetic modeling|carried out the statistical analyses|drafted the article	carried out the image analysis	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
6265355	30498919	PPS	2	conceived of the study and designed the study|carried out the image analysis|performed the kinetic modeling|carried out the statistical analyses|drafted the article	performed the kinetic modeling	Performed the experiments	Investigation|Methodology	YES
6265355	30498919	PPS	2	conceived of the study and designed the study|carried out the image analysis|performed the kinetic modeling|carried out the statistical analyses|drafted the article	carried out the statistical analyses	Analyzed the data	Formal analysis	YES
6265355	30498919	PPS	2	conceived of the study and designed the study|carried out the image analysis|performed the kinetic modeling|carried out the statistical analyses|drafted the article	drafted the article	Wrote the paper	Writing - Original Draft	YES
6265355	30498919	SC	2	drafted the article|supervised the study	drafted the article	Wrote the paper	Writing - Original Draft	YES
6265355	30498919	SC	2	drafted the article|supervised the study	supervised the study	-	Supervision	YES
6265355	30498919	ZC	2	carried out the image analysis	carried out the image analysis	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
5031564	27655587	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5031564	27655587	HW	2	conceived experiments|wrote the manuscript	conceived experiments	Conceived and designed the experiments	Conceptualization	YES
5031564	27655587	HW	2	conceived experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5031564	27655587	LC	2	conceived experiments|carried out the experiments|performed the statistical analysis|wrote the manuscript	conceived experiments	Conceived and designed the experiments	Conceptualization	YES
5031564	27655587	LC	2	conceived experiments|carried out the experiments|performed the statistical analysis|wrote the manuscript	carried out the experiments	Performed the experiments	Investigation	YES
5031564	27655587	LC	2	conceived experiments|carried out the experiments|performed the statistical analysis|wrote the manuscript	performed the statistical analysis	Analyzed the data	Formal analysis	YES
5031564	27655587	LC	2	conceived experiments|carried out the experiments|performed the statistical analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5031564	27655587	LY	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5031564	27655587	MW	2	performed the statistical analysis|wrote the manuscript	performed the statistical analysis	Analyzed the data	Formal analysis	YES
5031564	27655587	MW	2	performed the statistical analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5031564	27655587	SL	2	conceived experiments|performed the statistical analysis|wrote the manuscript	conceived experiments	Conceived and designed the experiments	Conceptualization	YES
5031564	27655587	SL	2	conceived experiments|performed the statistical analysis|wrote the manuscript	performed the statistical analysis	Analyzed the data	Formal analysis	YES
5031564	27655587	SL	2	conceived experiments|performed the statistical analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5733087	29312365	All authors	2	listed have made a substantial, direct and intellectual contribution to the work, and approved it for publication	listed have made a substantial, direct and intellectual contribution to the work, and approved it for publication	-	-	NO
5629566	28984191	BZ	PLoS5	Conceived and designed the experiments|Implemented the algorithm|Analyzed the results|Wrote the paper|Supervised the study	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5629566	28984191	BZ	PLoS5	Conceived and designed the experiments|Implemented the algorithm|Analyzed the results|Wrote the paper|Supervised the study	Implemented the algorithm	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5629566	28984191	BZ	PLoS5	Conceived and designed the experiments|Implemented the algorithm|Analyzed the results|Wrote the paper|Supervised the study	Analyzed the results	Analyzed the data	Formal analysis	YES
5629566	28984191	BZ	PLoS5	Conceived and designed the experiments|Implemented the algorithm|Analyzed the results|Wrote the paper|Supervised the study	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5629566	28984191	BZ	PLoS5	Conceived and designed the experiments|Implemented the algorithm|Analyzed the results|Wrote the paper|Supervised the study	Supervised the study	-	Supervision	YES
5629566	28984191	LX	PLoS5	Conceived and designed the experiments|Implemented the algorithm|Analyzed the results|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5629566	28984191	LX	PLoS5	Conceived and designed the experiments|Implemented the algorithm|Analyzed the results|Wrote the paper	Implemented the algorithm	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5629566	28984191	LX	PLoS5	Conceived and designed the experiments|Implemented the algorithm|Analyzed the results|Wrote the paper	Analyzed the results	Analyzed the data	Formal analysis	YES
5629566	28984191	LX	PLoS5	Conceived and designed the experiments|Implemented the algorithm|Analyzed the results|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5629566	28984191	MA	PLoS5	Conceived and designed the experiments|Implemented the algorithm|Performed the experiments|Analyzed the results|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5629566	28984191	MA	PLoS5	Conceived and designed the experiments|Implemented the algorithm|Performed the experiments|Analyzed the results|Wrote the paper	Implemented the algorithm	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5629566	28984191	MA	PLoS5	Conceived and designed the experiments|Implemented the algorithm|Performed the experiments|Analyzed the results|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
5629566	28984191	MA	PLoS5	Conceived and designed the experiments|Implemented the algorithm|Performed the experiments|Analyzed the results|Wrote the paper	Analyzed the results	Analyzed the data	Formal analysis	YES
5629566	28984191	MA	PLoS5	Conceived and designed the experiments|Implemented the algorithm|Performed the experiments|Analyzed the results|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5629566	28984191	XQ	PLoS5	Conceived and designed the experiments|Implemented the algorithm|Analyzed the results|Wrote the paper|Supervised the study	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5629566	28984191	XQ	PLoS5	Conceived and designed the experiments|Implemented the algorithm|Analyzed the results|Wrote the paper|Supervised the study	Implemented the algorithm	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5629566	28984191	XQ	PLoS5	Conceived and designed the experiments|Implemented the algorithm|Analyzed the results|Wrote the paper|Supervised the study	Analyzed the results	Analyzed the data	Formal analysis	YES
5629566	28984191	XQ	PLoS5	Conceived and designed the experiments|Implemented the algorithm|Analyzed the results|Wrote the paper|Supervised the study	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5629566	28984191	XQ	PLoS5	Conceived and designed the experiments|Implemented the algorithm|Analyzed the results|Wrote the paper|Supervised the study	Supervised the study	-	Supervision	YES
4414557	25923741	AB	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414557	25923741	AB	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4414557	25923741	IRH	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414557	25923741	IRH	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414557	25923741	IRH	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414557	25923741	KCS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414557	25923741	KCS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4414557	25923741	KCS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4414557	25923741	RCL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414557	25923741	RCL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414557	25923741	RCL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6265360	30498938	DT	2	carried out the phantom measurements, image reconstruction, and data analysis	carried out the phantom measurements, image reconstruction, and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
6265360	30498938	ED	2	contributed to the study design|were responsible for the patients and their treatment	contributed to the study design	Conceived and designed the experiments	Methodology	YES
6265360	30498938	ED	2	contributed to the study design|were responsible for the patients and their treatment	were responsible for the patients and their treatment	-	-	NO
6265360	30498938	EM-R	2	carried out the phantom measurements, image reconstruction, and data analysis	carried out the phantom measurements, image reconstruction, and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
6265360	30498938	JPP	2	contributed to the study design	contributed to the study design	Conceived and designed the experiments	Methodology	YES
6265360	30498938	LS	2	carried out the phantom measurements, image reconstruction, and data analysis|wrote the manuscript	carried out the phantom measurements, image reconstruction, and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
6265360	30498938	LS	2	carried out the phantom measurements, image reconstruction, and data analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6265360	30498938	MB	2	contributed to the study design	contributed to the study design	Conceived and designed the experiments	Methodology	YES
6265360	30498938	PE	2	helped with phantom measurements	helped with phantom measurements	Performed the experiments	Investigation	YES
6265360	30498938	POK	2	were responsible for the patients and their treatment	were responsible for the patients and their treatment	-	-	NO
6265360	30498938	SC	2	carried out the phantom measurements, image reconstruction, and data analysis	carried out the phantom measurements, image reconstruction, and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
1906860	17637828	AH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1906860	17637828	AH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1906860	17637828	AH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1906860	17637828	AH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1906860	17637828	CF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1906860	17637828	CF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1906860	17637828	CF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1906860	17637828	CF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1906860	17637828	CF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1906860	17637828	FT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1906860	17637828	FT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1906860	17637828	FT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1906860	17637828	FT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1906860	17637828	FT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1906860	17637828	HN	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1906860	17637828	HN	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1906860	17637828	HN	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1906860	17637828	JB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1906860	17637828	JB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1906860	17637828	JB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1906860	17637828	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1906860	17637828	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1906860	17637828	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1906860	17637828	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1906860	17637828	JN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1906860	17637828	JN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1906860	17637828	JN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1906860	17637828	JN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1906860	17637828	NM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1906860	17637828	NM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1906860	17637828	NM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1906860	17637828	XC	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6054140	30090244	C.S.	2	conceived the idea and designed the experiments|wrote the manuscript with input from all authors|supervised research	conceived the idea and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6054140	30090244	C.S.	2	conceived the idea and designed the experiments|wrote the manuscript with input from all authors|supervised research	wrote the manuscript with input from all authors	Wrote the paper	Writing - Original Draft	YES
6054140	30090244	C.S.	2	conceived the idea and designed the experiments|wrote the manuscript with input from all authors|supervised research	supervised research	-	Supervision	YES
6054140	30090244	D.D.P.	2	wrote the manuscript with input from all authors	wrote the manuscript with input from all authors	Wrote the paper	Writing - Original Draft	YES
6054140	30090244	H.-Y.H.	2	conceived the idea and designed the experiments|wrote the manuscript with input from all authors	conceived the idea and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6054140	30090244	H.-Y.H.	2	conceived the idea and designed the experiments|wrote the manuscript with input from all authors	wrote the manuscript with input from all authors	Wrote the paper	Writing - Original Draft	YES
6054140	30090244	H.N.	2	supervised research	supervised research	-	Supervision	YES
6054140	30090244	K.A.R.	2	wrote the manuscript with input from all authors	wrote the manuscript with input from all authors	Wrote the paper	Writing - Original Draft	YES
6054140	30090244	K.U.W.	2	supervised research	supervised research	-	Supervision	YES
6054140	30090244	M.N.	2	conceived the idea and designed the experiments|wrote the manuscript with input from all authors|supervised research	conceived the idea and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6054140	30090244	M.N.	2	conceived the idea and designed the experiments|wrote the manuscript with input from all authors|supervised research	wrote the manuscript with input from all authors	Wrote the paper	Writing - Original Draft	YES
6054140	30090244	M.N.	2	conceived the idea and designed the experiments|wrote the manuscript with input from all authors|supervised research	supervised research	-	Supervision	YES
6054140	30090244	N.-H.L.	2	wrote the manuscript with input from all authors|wrote the manuscript with input from all authors	wrote the manuscript with input from all authors	Wrote the paper	Writing - Original Draft	YES
6054140	30090244	N.-H.L.	2	wrote the manuscript with input from all authors|wrote the manuscript with input from all authors	wrote the manuscript with input from all authors	Wrote the paper	Writing - Original Draft	YES
6054140	30090244	O.P.	2	wrote the manuscript with input from all authors|supervised research	wrote the manuscript with input from all authors	Wrote the paper	Writing - Original Draft	YES
6054140	30090244	O.P.	2	wrote the manuscript with input from all authors|supervised research	supervised research	-	Supervision	YES
6054140	30090244	P.F.	2	wrote the manuscript with input from all authors	wrote the manuscript with input from all authors	Wrote the paper	Writing - Original Draft	YES
5045449	27696305	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5045449	27696305	DM	2	conducted the experiments	conducted the experiments	Performed the experiments	Investigation	YES
5045449	27696305	DZ	2	helped with the wrote the paper with	helped with the wrote the paper with	Wrote the paper	Writing - Original Draft	YES
5045449	27696305	HX	2	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5045449	27696305	SD	2	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5045449	27696305	YD	2	designed the experiments|conducted the experiments|analyzed data|wrote the paper with	designed the experiments	Conceived and designed the experiments	Methodology	YES
5045449	27696305	YD	2	designed the experiments|conducted the experiments|analyzed data|wrote the paper with	conducted the experiments	Performed the experiments	Investigation	YES
5045449	27696305	YD	2	designed the experiments|conducted the experiments|analyzed data|wrote the paper with	analyzed data	Analyzed the data	Formal analysis	YES
5045449	27696305	YD	2	designed the experiments|conducted the experiments|analyzed data|wrote the paper with	wrote the paper with	Wrote the paper	Writing - Original Draft	YES
5045449	27696305	ZJ	2	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5629567	28984205	DCS	2	assisted with study design	assisted with study design	Conceived and designed the experiments	Methodology	YES
5629567	28984205	QS	2	performed analysis for the study	performed analysis for the study	Performed the experiments	Investigation	YES
5629567	28984205	SZ	2	performed the majority of the analyses	performed the majority of the analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5629567	28984205	YG	2	designed and wrote the manuscript	designed and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
5629567	28984205	YS	2	designed and wrote the manuscript	designed and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
5733115	29255474	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5733115	29255474	B-XC	2	conceived and designed the experiments, analyzed the data and wrote the paper|critically revised the manuscript	conceived and designed the experiments, analyzed the data and wrote the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
5733115	29255474	B-XC	2	conceived and designed the experiments, analyzed the data and wrote the paper|critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5733115	29255474	Q-JL	2	for the revision of the manuscript	for the revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5733115	29255474	The authors	2	apologize for these errors and state that this does not change the scientific conclusions of the article in any way	apologize for these errors and state that this does not change the scientific conclusions of the article in any way	Analyzed the data	Formal analysis	YES
5733115	29255474	W-NZ	2	offered the help for photography	offered the help for photography	Performed the experiments	Investigation|Visualization	YES
5733115	29255474	W-YL	2	conceived and designed the experiments, analyzed the data and wrote the paper|carried out bioinformatics analysis and provided funding|critically revised the manuscript	conceived and designed the experiments, analyzed the data and wrote the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
5733115	29255474	W-YL	2	conceived and designed the experiments, analyzed the data and wrote the paper|carried out bioinformatics analysis and provided funding|critically revised the manuscript	carried out bioinformatics analysis and provided funding	Performed the experiments	Formal analysis|Funding acquisition|Investigation	YES
5733115	29255474	W-YL	2	conceived and designed the experiments, analyzed the data and wrote the paper|carried out bioinformatics analysis and provided funding|critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5733115	29255474	Z-JC	2	critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5733115	29255474	ZC	2	for the revision of the manuscript	for the revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4609774	26509164	Carmela R. Balistreri	2	was involved in conception and design of the paper|was involved in drafting the paper, its critical revision, and supervision|gave the final approval of the version to be published	was involved in conception and design of the paper	Conceived and designed the experiments	Conceptualization	YES
4609774	26509164	Carmela R. Balistreri	2	was involved in conception and design of the paper|was involved in drafting the paper, its critical revision, and supervision|gave the final approval of the version to be published	was involved in drafting the paper, its critical revision, and supervision	Wrote the paper	Supervision|Writing - Original Draft|Writing - Review & Editing	YES
4609774	26509164	Carmela R. Balistreri	2	was involved in conception and design of the paper|was involved in drafting the paper, its critical revision, and supervision|gave the final approval of the version to be published	gave the final approval of the version to be published	-	-	NO
4609774	26509164	Silvio Buffa	2	performed a research on literature data about methods used for evaluating epc cells	performed a research on literature data about methods used for evaluating epc cells	Performed the experiments	Formal analysis|Investigation	YES
4414559	25924011	AK	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4414559	25924011	AK	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4414559	25924011	MKE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414559	25924011	MKE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414559	25924011	MKE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414559	25924011	MKE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414559	25924011	MKE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414559	25924011	OE	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4414559	25924011	OE	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
6277398	30511175	AB	2	created the design of the study and analysis and supervised the project|participated in the design of the study and analysis and contributed to the manuscript revision and editing	created the design of the study and analysis and supervised the project	Conceived and designed the experiments	Methodology|Supervision	YES
6277398	30511175	AB	2	created the design of the study and analysis and supervised the project|participated in the design of the study and analysis and contributed to the manuscript revision and editing	participated in the design of the study and analysis and contributed to the manuscript revision and editing	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
6277398	30511175	BvR	2	collected the data and edited and revised the manuscript	collected the data and edited and revised the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
6277398	30511175	EW	2	collected the data and edited and revised the manuscript	collected the data and edited and revised the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
6277398	30511175	HvdP	2	collected the data and edited and revised the manuscript	collected the data and edited and revised the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
6277398	30511175	KH	2	collected the data and edited and revised the manuscript	collected the data and edited and revised the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
6277398	30511175	KJ	2	contributed to statistical analysis and manuscript revision	contributed to statistical analysis and manuscript revision	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
6277398	30511175	MD	2	participated in the design of the study and analysis and contributed to the manuscript revision and editing	participated in the design of the study and analysis and contributed to the manuscript revision and editing	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
6277398	30511175	OB	2	collected the data and edited and revised the manuscript	collected the data and edited and revised the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
6277398	30511175	RB	2	collected the data and edited and revised the manuscript	collected the data and edited and revised the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
6277398	30511175	RVO	2	participated in the design of the study and analysis and contributed to the manuscript revision and editing	participated in the design of the study and analysis and contributed to the manuscript revision and editing	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
6277398	30511175	SH	2	collected the data and edited and revised the manuscript	collected the data and edited and revised the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
6277398	30511175	TK	2	collected and analyzed the data, and drafted the manuscript	collected and analyzed the data, and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6277398	30511175	WP	2	collected the data and edited and revised the manuscript	collected the data and edited and revised the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
1910608	17637839	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1910608	17637839	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1910608	17637839	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1910608	17637839	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1910608	17637839	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1910608	17637839	JP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1910608	17637839	PG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1910608	17637839	PG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1910608	17637839	RS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1910608	17637839	RS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1910608	17637839	RS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1910608	17637839	RS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1910608	17637839	RW	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1910608	17637839	RW	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4111876	25147770	All authors	2	were involved in the discussion of the data, read and approved the final text	were involved in the discussion of the data, read and approved the final text	-	-	NO
4111876	25147770	F.B.	2	contributed to the data collection, laboratory measurements and provided advice on methodology	contributed to the data collection, laboratory measurements and provided advice on methodology	Performed the experiments	Investigation|Methodology	YES
4111876	25147770	G.L.	2	participated in collection of data, laboratory measurements and physical examination of the study participants	participated in collection of data, laboratory measurements and physical examination of the study participants	Performed the experiments	Investigation	YES
4111876	25147770	J.O.O.	2	supervised the project, participated in the design of the study, contributed to the draft and critical revision of the manuscript|has given final approval of the version to be published	supervised the project, participated in the design of the study, contributed to the draft and critical revision of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
4111876	25147770	J.O.O.	2	supervised the project, participated in the design of the study, contributed to the draft and critical revision of the manuscript|has given final approval of the version to be published	has given final approval of the version to be published	-	-	NO
4111876	25147770	L.D.	2	coordinated the project, participated in the design of the study and collection of data	coordinated the project, participated in the design of the study and collection of data	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Project administration	YES
4111876	25147770	M.B.	2	participated in the design of the study, advised on statistical analysis, contributed to the draft and critical revision of the paper	participated in the design of the study, advised on statistical analysis, contributed to the draft and critical revision of the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
4111876	25147770	M.C.	2	planned the study and contributed to the draft and critical revision of the paper	planned the study and contributed to the draft and critical revision of the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
4111876	25147770	N.P.	2	designed the study, collected the data, performed statistical analysis and wrote the manuscript	designed the study, collected the data, performed statistical analysis and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5733117	29312378	DX	2	provided assistance with subcellular localization and data analysis	provided assistance with subcellular localization and data analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5733117	29312378	HW	2	generated the transgenic materials and performed the experiments	generated the transgenic materials and performed the experiments	Performed the experiments	Investigation	YES
5733117	29312378	JF	2	designed and performed the experiments and wrote the manuscript	designed and performed the experiments and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5733117	29312378	LX	2	designed the experiments and wrote the manuscript	designed the experiments and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5733117	29312378	RL	2	provided assistance with subcellular localization and data analysis	provided assistance with subcellular localization and data analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5733117	29312378	SM	2	provided assistance with subcellular localization and data analysis	provided assistance with subcellular localization and data analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5047869	27699701	Both authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5047869	27699701	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5629589	28984181	FS	2	conceived the study, designed the framework of the paper and finalized the manuscript	conceived the study, designed the framework of the paper and finalized the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
5629589	28984181	JR	2	participated in the real data analysis	participated in the real data analysis	Analyzed the data	Formal analysis	YES
5629589	28984181	KT	2	participated in the real data analysis	participated in the real data analysis	Analyzed the data	Formal analysis	YES
5629589	28984181	MSW	2	conceived the study, designed the framework of the paper and finalized the manuscript	conceived the study, designed the framework of the paper and finalized the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
5629589	28984181	XB	2	did the simulation studies, proved the theorems, and wrote the manuscript	did the simulation studies, proved the theorems, and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4414560	25923715	CN	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414560	25923715	CN	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414560	25923715	CWM	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414560	25923715	OC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414560	25923715	OC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414560	25923715	OC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414560	25923715	PA	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414560	25923715	PA	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414560	25923715	PA	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414560	25923715	TP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414560	25923715	TP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414560	25923715	TP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414560	25923715	TP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414560	25923715	TP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6277401	30511194	CL	2	helped to draft the manuscript	helped to draft the manuscript	Wrote the paper	Writing - Original Draft	YES
6277401	30511194	FB	2	participated in the design of the study	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
6277401	30511194	MR	2	expertise, critical reading and editing of the manuscript	expertise, critical reading and editing of the manuscript	Wrote the paper	Writing - Review & Editing	YES
6277401	30511194	NJS	2	appropriated the mr-pet hardware and resources	appropriated the mr-pet hardware and resources	Contributed reagents/materials/analysis tools	Resources	YES
1910609	17637829	IH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1910609	17637829	IH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1910609	17637829	IH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1910609	17637829	PM	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1910609	17637829	PM	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1910609	17637829	TM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1910609	17637829	TM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1910609	17637829	TM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1910609	17637829	TM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414561	25923701	LS	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4414561	25923701	PL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414561	25923701	PL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414561	25923701	PL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414561	25923701	XX	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4414561	25923701	XZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414561	25923701	XZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414561	25923701	XZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414561	25923701	XZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414561	25923701	YM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414561	25923701	YM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414561	25923701	YM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414561	25923701	YM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414561	25923701	YM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414561	25923701	YY	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414561	25923701	ZY	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5629590	28984202	ACE	2	performed bioinformatics and statistical analysis for alternate algorithm comparisons and orthogonal long-read sequencing validation	performed bioinformatics and statistical analysis for alternate algorithm comparisons and orthogonal long-read sequencing validation	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Software|Validation	YES
5629590	28984202	DAW	2	provided support and management of the project	provided support and management of the project	-	Project administration	YES
5629590	28984202	DMM	2	performed and managed sequencing	performed and managed sequencing	Performed the experiments	Investigation	YES
5629590	28984202	JRL	2	provided support and management of the project	provided support and management of the project	-	Project administration	YES
5629590	28984202	KCW	2	provided support and management of the project	provided support and management of the project	-	Project administration	YES
5629590	28984202	MW	2	performed and managed sequencing	performed and managed sequencing	Performed the experiments	Investigation	YES
5629590	28984202	OAH	2	developed, implemented and refined the algorithm|performed bioinformatics and statistical analysis for alternate algorithm comparisons and orthogonal long-read sequencing validation|wrote the manuscript	developed, implemented and refined the algorithm	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5629590	28984202	OAH	2	developed, implemented and refined the algorithm|performed bioinformatics and statistical analysis for alternate algorithm comparisons and orthogonal long-read sequencing validation|wrote the manuscript	performed bioinformatics and statistical analysis for alternate algorithm comparisons and orthogonal long-read sequencing validation	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Software|Validation	YES
5629590	28984202	OAH	2	developed, implemented and refined the algorithm|performed bioinformatics and statistical analysis for alternate algorithm comparisons and orthogonal long-read sequencing validation|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5629590	28984202	RAG	2	provided support and management of the project	provided support and management of the project	-	Project administration	YES
5629590	28984202	WJS	2	provided support and management of the project	provided support and management of the project	-	Project administration	YES
5629590	28984202	YH	2	performed and managed sequencing	performed and managed sequencing	Performed the experiments	Investigation	YES
5629590	28984202	YL	2	performed primary analysis mapping and adapter trimming on the nextera sequencing data	performed primary analysis mapping and adapter trimming on the nextera sequencing data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5047870	27699703	All authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5047870	27699703	BS	2	conducted the experiments and analyzed data	conducted the experiments and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5047870	27699703	C. All	2	the authors read and approved the final manuscript	the authors read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5047870	27699703	GP	2	conducted the experiments and analyzed data	conducted the experiments and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5047870	27699703	MDP	2	conceived the ideas and designed the research experiments|conducted the experiments and analyzed data	conceived the ideas and designed the research experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5047870	27699703	MDP	2	conceived the ideas and designed the research experiments|conducted the experiments and analyzed data	conducted the experiments and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5047870	27699703	Mukesh Kumar	2	for technical assistance with the bioreactor runs	for technical assistance with the bioreactor runs	Performed the experiments	Investigation	YES
5047870	27699703	SVM	2	modelling of the data	modelling of the data	Performed the experiments	Methodology	YES
5047870	27699703	UCB	2	conceived the ideas and designed the research experiments	conceived the ideas and designed the research experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5733346	29326741	BD	7	analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5733346	29326741	BD	7	analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5733346	29326741	BZ	7	planned and designed the research|analyzed the data|wrote the manuscript	planned and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5733346	29326741	BZ	7	planned and designed the research|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5733346	29326741	BZ	7	planned and designed the research|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5733346	29326741	FL	7	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5733346	29326741	FY	7	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5733346	29326741	GW	7	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5733346	29326741	JW	7	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5733346	29326741	QW	7	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5733346	29326741	SQ	7	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5733346	29326741	TC	7	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5733346	29326741	TL	7	planned and designed the research|performed the experiments|analyzed the data|wrote the manuscript	planned and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5733346	29326741	TL	7	planned and designed the research|performed the experiments|analyzed the data|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5733346	29326741	TL	7	planned and designed the research|performed the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5733346	29326741	TL	7	planned and designed the research|performed the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5733346	29326741	XZ	7	planned and designed the research|analyzed the data|wrote the manuscript	planned and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5733346	29326741	XZ	7	planned and designed the research|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5733346	29326741	XZ	7	planned and designed the research|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5733346	29326741	YY	7	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5733346	29326741	ZG	7	planned and designed the research|performed the experiments|analyzed the data|wrote the manuscript	planned and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5733346	29326741	ZG	7	planned and designed the research|performed the experiments|analyzed the data|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5733346	29326741	ZG	7	planned and designed the research|performed the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5733346	29326741	ZG	7	planned and designed the research|performed the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4414562	25923215	HC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414562	25923215	HC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414562	25923215	HC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414562	25923215	HS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414562	25923215	HS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414562	25923215	HS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414562	25923215	HS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414562	25923215	KF	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414562	25923215	KF	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414562	25923215	KF	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414562	25923215	PN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414562	25923215	PN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414562	25923215	PN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414562	25923215	PN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414562	25923215	RS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414562	25923215	RS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414562	25923215	RS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414562	25923215	RS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414562	25923215	YF	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414562	25923215	YF	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414562	25923215	YF	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414562	25923215	ZH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414562	25923215	ZH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414562	25923215	ZH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6277402	30511173	CBF	2	participated in the data acquisition	participated in the data acquisition	Performed the experiments	Investigation	YES
6277402	30511173	CD	2	participated in the data acquisition	participated in the data acquisition	Performed the experiments	Investigation	YES
6277402	30511173	IL	2	performed the statistical analysis|helped to draft the manuscript	performed the statistical analysis	Analyzed the data	Formal analysis	YES
6277402	30511173	IL	2	performed the statistical analysis|helped to draft the manuscript	helped to draft the manuscript	Wrote the paper	Writing - Original Draft	YES
6277402	30511173	NA	2	conceived the study and its design|performed the statistical analysis|helped to draft the manuscript	conceived the study and its design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6277402	30511173	NA	2	conceived the study and its design|performed the statistical analysis|helped to draft the manuscript	performed the statistical analysis	Analyzed the data	Formal analysis	YES
6277402	30511173	NA	2	conceived the study and its design|performed the statistical analysis|helped to draft the manuscript	helped to draft the manuscript	Wrote the paper	Writing - Original Draft	YES
6277402	30511173	RC	2	conceived the study and its design|performed data acquisition and drafted the manuscript|performed the statistical analysis	conceived the study and its design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6277402	30511173	RC	2	conceived the study and its design|performed data acquisition and drafted the manuscript|performed the statistical analysis	performed data acquisition and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6277402	30511173	RC	2	conceived the study and its design|performed data acquisition and drafted the manuscript|performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
6277402	30511173	SB	2	helped to draft the manuscript	helped to draft the manuscript	Wrote the paper	Writing - Original Draft	YES
1910610	17637831	AA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1910610	17637831	AA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1910610	17637831	AA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1910610	17637831	AR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1910610	17637831	AR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1910610	17637831	AR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1910610	17637831	BI	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1910610	17637831	BI	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1910610	17637831	EF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1910610	17637831	EF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1910610	17637831	EF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1910610	17637831	EF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1910610	17637831	JA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1910610	17637831	JA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1910610	17637831	JA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1910610	17637831	JA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1910610	17637831	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1910610	17637831	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1910610	17637831	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1910610	17637831	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5629612	28984207	GIA	2	conducted in the initial planning and discussion	conducted in the initial planning and discussion	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5629612	28984207	JR	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5629612	28984207	JZ	2	conducted in the initial planning and discussion	conducted in the initial planning and discussion	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5629612	28984207	KC	2	conducted in the initial planning and discussion	conducted in the initial planning and discussion	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5629612	28984207	WZ	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5629612	28984207	YG	2	conducted in the initial planning and discussion	conducted in the initial planning and discussion	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5629612	28984207	ZL	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5629612	28984207	ZZ	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4414563	25922938	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414563	25922938	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414563	25922938	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414563	25922938	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414563	25922938	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414563	25922938	SD	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414563	25922938	SD	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414563	25922938	SD	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414563	25922938	TM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414563	25922938	TM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414563	25922938	TM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414563	25922938	TM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5047873	27699704	KZ	1	Experimentation	Experimentation	Performed the experiments	Investigation	YES
5047873	27699704	LC	1	Experimentation	Experimentation	Performed the experiments	Investigation	YES
5047873	27699704	SD	1	Planning and designing of study|Experimentation|Result analysis|Manuscript drafting	Planning and designing of study	Conceived and designed the experiments	Methodology	YES
5047873	27699704	SD	1	Planning and designing of study|Experimentation|Result analysis|Manuscript drafting	Experimentation	Performed the experiments	Investigation	YES
5047873	27699704	SD	1	Planning and designing of study|Experimentation|Result analysis|Manuscript drafting	Result analysis	-	-	NO
5047873	27699704	SD	1	Planning and designing of study|Experimentation|Result analysis|Manuscript drafting	Manuscript drafting	Wrote the paper	Writing - Original Draft	YES
5047873	27699704	XF	1	Experimentation	Experimentation	Performed the experiments	Investigation	YES
5047873	27699704	YP	1	Planning and designing of study	Planning and designing of study	Conceived and designed the experiments	Methodology	YES
5047873	27699704	ZL	1	Planning and designing of study|Result analysis	Planning and designing of study	Conceived and designed the experiments	Methodology	YES
5047873	27699704	ZL	1	Planning and designing of study|Result analysis	Result analysis	-	-	NO
5733352	29326739	JL	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5733352	29326739	JL	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5733352	29326739	JL	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5733352	29326739	JL	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5733352	29326739	MK	PLoS52	originally formulated the idea|conceived and designed the experiments|wrote the manuscript	originally formulated the idea	Conceived and designed the experiments	Conceptualization	YES
5733352	29326739	MK	PLoS52	originally formulated the idea|conceived and designed the experiments|wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5733352	29326739	MK	PLoS52	originally formulated the idea|conceived and designed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5733352	29326739	SL	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5733352	29326739	SL	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5733352	29326739	SL	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5733352	29326739	SL	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6281542	30519791	BK	2	were responsible for the study at the mayo clinic and provide the data and input to the manuscript preparation	were responsible for the study at the mayo clinic and provide the data and input to the manuscript preparation	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Original Draft	YES
6281542	30519791	CCR	2	performed centiloid analysis of the subjects using spm8 and provided valuable input into the discussion and review of the manuscript	performed centiloid analysis of the subjects using spm8 and provided valuable input into the discussion and review of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
6281542	30519791	CJB	2	provided valuable contribution in the analysis of the data, preparation and review of the manuscript	provided valuable contribution in the analysis of the data, preparation and review of the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft|Writing - Review & Editing	YES
6281542	30519791	DK	2	were responsible for the study at the mayo clinic and provide the data and input to the manuscript preparation	were responsible for the study at the mayo clinic and provide the data and input to the manuscript preparation	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Original Draft	YES
6281542	30519791	LCP	2	developed the fsl centiloid process and carried out the analysis of the data using this pipeline	developed the fsl centiloid process and carried out the analysis of the data using this pipeline	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
6281542	30519791	PMOD	2	prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
6281542	30519791	VD	2	performed centiloid analysis of the subjects using spm8 and provided valuable input into the discussion and review of the manuscript	performed centiloid analysis of the subjects using spm8 and provided valuable input into the discussion and review of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
6281542	30519791	VJL	2	were responsible for the study at the mayo clinic and provide the data and input to the manuscript preparation	were responsible for the study at the mayo clinic and provide the data and input to the manuscript preparation	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Original Draft	YES
6281542	30519791	VLV	2	performed centiloid analysis of the subjects using spm8 and provided valuable input into the discussion and review of the manuscript	performed centiloid analysis of the subjects using spm8 and provided valuable input into the discussion and review of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
1910611	17637832	MV	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4609779	26509155	Ayako Hakucho	PLoS52	performed the research|analyzed and interpreted the data	performed the research	Performed the experiments	Investigation	YES
4609779	26509155	Ayako Hakucho	PLoS52	performed the research|analyzed and interpreted the data	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
4609779	26509155	Jinyao Liu	PLoS52	designed the research|performed the research|analyzed and interpreted the data|wrote the paper	designed the research	Conceived and designed the experiments	Methodology	YES
4609779	26509155	Jinyao Liu	PLoS52	designed the research|performed the research|analyzed and interpreted the data|wrote the paper	performed the research	Performed the experiments	Investigation	YES
4609779	26509155	Jinyao Liu	PLoS52	designed the research|performed the research|analyzed and interpreted the data|wrote the paper	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
4609779	26509155	Jinyao Liu	PLoS52	designed the research|performed the research|analyzed and interpreted the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4609779	26509155	Tatsuya Fujimiya	PLoS52	analyzed and interpreted the data	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5047876	27699702	AK	2	supervised the research	supervised the research	-	Supervision	YES
5047876	27699702	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5047876	27699702	KI	2	designed the study, conducted the experiments and drafted the manuscript	designed the study, conducted the experiments and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5047876	27699702	Kazuhiro Hoshino	2	for his helpful advice	for his helpful advice	-	-	NO
5047876	27699702	TH	2	supervised the research	supervised the research	-	Supervision	YES
5047876	27699702	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5733359	29326736	AI	PLoS52	conceived and designed the study|performed the experiments|analyzed the data|contributed to the drafting and writing of the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5733359	29326736	AI	PLoS52	conceived and designed the study|performed the experiments|analyzed the data|contributed to the drafting and writing of the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5733359	29326736	AI	PLoS52	conceived and designed the study|performed the experiments|analyzed the data|contributed to the drafting and writing of the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5733359	29326736	AI	PLoS52	conceived and designed the study|performed the experiments|analyzed the data|contributed to the drafting and writing of the manuscript	contributed to the drafting and writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5733359	29326736	All authors	PLoS52	critically read and approved the manuscript	critically read and approved the manuscript	-	-	NO
5733359	29326736	FN	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5733359	29326736	MF	PLoS52	conceived and designed the study|performed the experiments|analyzed the data|drafted the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5733359	29326736	MF	PLoS52	conceived and designed the study|performed the experiments|analyzed the data|drafted the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5733359	29326736	MF	PLoS52	conceived and designed the study|performed the experiments|analyzed the data|drafted the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5733359	29326736	MF	PLoS52	conceived and designed the study|performed the experiments|analyzed the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5733359	29326736	RB	PLoS52	conceived and designed the study|performed the experiments|analyzed the data|contributed to the drafting and writing of the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5733359	29326736	RB	PLoS52	conceived and designed the study|performed the experiments|analyzed the data|contributed to the drafting and writing of the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5733359	29326736	RB	PLoS52	conceived and designed the study|performed the experiments|analyzed the data|contributed to the drafting and writing of the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5733359	29326736	RB	PLoS52	conceived and designed the study|performed the experiments|analyzed the data|contributed to the drafting and writing of the manuscript	contributed to the drafting and writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5733359	29326736	RP	PLoS52	conceived and designed the study|analyzed the data|drafted the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5733359	29326736	RP	PLoS52	conceived and designed the study|analyzed the data|drafted the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5733359	29326736	RP	PLoS52	conceived and designed the study|analyzed the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4414564	25923742	GL	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414564	25923742	GL	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414564	25923742	GY	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4414564	25923742	GY	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4414564	25923742	HJL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414564	25923742	HJL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414564	25923742	HJL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414564	25923742	KLC	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414564	25923742	KLC	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414564	25923742	KLC	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414564	25923742	KLC	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414564	25923742	PCC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414564	25923742	PCC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414564	25923742	PCC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414564	25923742	PCC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414564	25923742	PCC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6291411	30543050	AVDG	2	are responsible for the data acquisition|are responsible for the manuscript writing|are responsible for the approval of the final form	are responsible for the data acquisition	Performed the experiments	Investigation	YES
6291411	30543050	AVDG	2	are responsible for the data acquisition|are responsible for the manuscript writing|are responsible for the approval of the final form	are responsible for the manuscript writing	Wrote the paper	Writing - Original Draft	YES
6291411	30543050	AVDG	2	are responsible for the data acquisition|are responsible for the manuscript writing|are responsible for the approval of the final form	are responsible for the approval of the final form	-	-	NO
6291411	30543050	FC	2	are responsible for the data analysis and critical evaluation of the results|are responsible for the manuscript writing|are responsible for the approval of the final form	are responsible for the data analysis and critical evaluation of the results	Analyzed the data	Formal analysis	YES
6291411	30543050	FC	2	are responsible for the data analysis and critical evaluation of the results|are responsible for the manuscript writing|are responsible for the approval of the final form	are responsible for the manuscript writing	Wrote the paper	Writing - Original Draft	YES
6291411	30543050	FC	2	are responsible for the data analysis and critical evaluation of the results|are responsible for the manuscript writing|are responsible for the approval of the final form	are responsible for the approval of the final form	-	-	NO
6291411	30543050	JOP	2	are responsible for the design of the study|are responsible for the data analysis and critical evaluation of the results|are responsible for the approval of the final form	are responsible for the design of the study	Conceived and designed the experiments	Methodology	YES
6291411	30543050	JOP	2	are responsible for the design of the study|are responsible for the data analysis and critical evaluation of the results|are responsible for the approval of the final form	are responsible for the data analysis and critical evaluation of the results	Analyzed the data	Formal analysis	YES
6291411	30543050	JOP	2	are responsible for the design of the study|are responsible for the data analysis and critical evaluation of the results|are responsible for the approval of the final form	are responsible for the approval of the final form	-	-	NO
6291411	30543050	PM	2	are responsible for the data acquisition|are responsible for patients selection and follow up|are responsible for the approval of the final form	are responsible for the data acquisition	Performed the experiments	Investigation	YES
6291411	30543050	PM	2	are responsible for the data acquisition|are responsible for patients selection and follow up|are responsible for the approval of the final form	are responsible for patients selection and follow up	-	-	NO
6291411	30543050	PM	2	are responsible for the data acquisition|are responsible for patients selection and follow up|are responsible for the approval of the final form	are responsible for the approval of the final form	-	-	NO
6291411	30543050	RM	2	are responsible for the design of the study|are responsible for patients selection and follow up|are responsible for the approval of the final form	are responsible for the design of the study	Conceived and designed the experiments	Methodology	YES
6291411	30543050	RM	2	are responsible for the design of the study|are responsible for patients selection and follow up|are responsible for the approval of the final form	are responsible for patients selection and follow up	-	-	NO
6291411	30543050	RM	2	are responsible for the design of the study|are responsible for patients selection and follow up|are responsible for the approval of the final form	are responsible for the approval of the final form	-	-	NO
6291411	30543050	SB	2	are responsible for the design of the study|are responsible for the data analysis and critical evaluation of the results|are responsible for the approval of the final form	are responsible for the design of the study	Conceived and designed the experiments	Methodology	YES
6291411	30543050	SB	2	are responsible for the design of the study|are responsible for the data analysis and critical evaluation of the results|are responsible for the approval of the final form	are responsible for the data analysis and critical evaluation of the results	Analyzed the data	Formal analysis	YES
6291411	30543050	SB	2	are responsible for the design of the study|are responsible for the data analysis and critical evaluation of the results|are responsible for the approval of the final form	are responsible for the approval of the final form	-	-	NO
6291411	30543050	SG	2	are responsible for the design of the study|are responsible for the data analysis and critical evaluation of the results|are responsible for the manuscript writing|are responsible for the approval of the final form	are responsible for the design of the study	Conceived and designed the experiments	Methodology	YES
6291411	30543050	SG	2	are responsible for the design of the study|are responsible for the data analysis and critical evaluation of the results|are responsible for the manuscript writing|are responsible for the approval of the final form	are responsible for the data analysis and critical evaluation of the results	Analyzed the data	Formal analysis	YES
6291411	30543050	SG	2	are responsible for the design of the study|are responsible for the data analysis and critical evaluation of the results|are responsible for the manuscript writing|are responsible for the approval of the final form	are responsible for the manuscript writing	Wrote the paper	Writing - Original Draft	YES
6291411	30543050	SG	2	are responsible for the design of the study|are responsible for the data analysis and critical evaluation of the results|are responsible for the manuscript writing|are responsible for the approval of the final form	are responsible for the approval of the final form	-	-	NO
6291411	30543050	TZ	2	are responsible for the design of the study|are responsible for patients selection and follow up|are responsible for the approval of the final form	are responsible for the design of the study	Conceived and designed the experiments	Methodology	YES
6291411	30543050	TZ	2	are responsible for the design of the study|are responsible for patients selection and follow up|are responsible for the approval of the final form	are responsible for patients selection and follow up	-	-	NO
6291411	30543050	TZ	2	are responsible for the design of the study|are responsible for patients selection and follow up|are responsible for the approval of the final form	are responsible for the approval of the final form	-	-	NO
6291411	30543050	VG	2	are responsible for patients selection and follow up|are responsible for the data analysis and critical evaluation of the results|are responsible for the approval of the final form	are responsible for patients selection and follow up	-	-	NO
6291411	30543050	VG	2	are responsible for patients selection and follow up|are responsible for the data analysis and critical evaluation of the results|are responsible for the approval of the final form	are responsible for the data analysis and critical evaluation of the results	Analyzed the data	Formal analysis	YES
6291411	30543050	VG	2	are responsible for patients selection and follow up|are responsible for the data analysis and critical evaluation of the results|are responsible for the approval of the final form	are responsible for the approval of the final form	-	-	NO
5629613	28984208	All authors	2	edited and approved the final manuscript	edited and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5629613	28984208	GH	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5629613	28984208	PJ	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5629613	28984208	ZZ	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
1910612	17637833	AN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1910612	17637833	AN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1910612	17637833	AN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1910612	17637833	AN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1910612	17637833	AZ	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1910612	17637833	AZ	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1910612	17637833	BC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1910612	17637833	BC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1910612	17637833	BC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1910612	17637833	BC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1910612	17637833	BC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1910612	17637833	KH	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1910612	17637833	KH	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1910612	17637833	KV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1910612	17637833	KV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1910612	17637833	KV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1910612	17637833	KV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1910612	17637833	LF	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1910612	17637833	PB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1910612	17637833	PB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1910612	17637833	PB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1910612	17637833	SD	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1910612	17637833	SD	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1910612	17637833	SY	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1910612	17637833	SY	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1910612	17637833	SY	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1910612	17637833	TF	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1910612	17637833	WS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1910612	17637833	WS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1910612	17637833	WS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1910612	17637833	WT	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1910612	17637833	WT	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1910612	17637833	YH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
6292827	30547248	DVW	2	contributed to the design of the study, data acquisition, monitoring and interpretation, and critically revised the manuscript	contributed to the design of the study, data acquisition, monitoring and interpretation, and critically revised the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Supervision|Writing - Review & Editing	YES
6292827	30547248	JDV	2	contributed to the data acquisition, monitoring and interpretation, and critically revised the manuscript	contributed to the data acquisition, monitoring and interpretation, and critically revised the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Supervision|Writing - Review & Editing	YES
6292827	30547248	KVL	2	contributed to the design of the study, data acquisition, monitoring and interpretation, and critically revised the manuscript	contributed to the design of the study, data acquisition, monitoring and interpretation, and critically revised the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Supervision|Writing - Review & Editing	YES
6292827	30547248	MD	2	contributed to the design of the study, data analysis and interpretation, and drafted the manuscript	contributed to the design of the study, data analysis and interpretation, and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Original Draft	YES
6292827	30547248	MK	2	contributed to the design of the study, data analysis and interpretation, and finalized the manuscript	contributed to the design of the study, data analysis and interpretation, and finalized the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Review & Editing	YES
6292827	30547248	PVD	2	contributed to the design of the study, data monitoring and interpretation, and critically revised the manuscript	contributed to the design of the study, data monitoring and interpretation, and critically revised the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Supervision|Writing - Review & Editing	YES
5047877	27699705	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5047877	27699705	BLRD	2	conducted the batch study experiments, determined the kinetic parameters using the model, and analyzed the experimental data	conducted the batch study experiments, determined the kinetic parameters using the model, and analyzed the experimental data	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5047877	27699705	FS	2	helped interpret data	helped interpret data	Analyzed the data	Formal analysis	YES
5047877	27699705	JPP	2	helped interpret data	helped interpret data	Analyzed the data	Formal analysis	YES
5047877	27699705	RN	2	helped interpret data	helped interpret data	Analyzed the data	Formal analysis	YES
5047877	27699705	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5629616	28984193	DZ	2	conceived the idea and designed the system|drafted the manuscript	conceived the idea and designed the system	Conceived and designed the experiments	Conceptualization	YES
5629616	28984193	DZ	2	conceived the idea and designed the system|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5629616	28984193	GS	2	conceived the idea and designed the system|implemented and tested the system|drafted the manuscript	conceived the idea and designed the system	Conceived and designed the experiments	Conceptualization	YES
5629616	28984193	GS	2	conceived the idea and designed the system|implemented and tested the system|drafted the manuscript	implemented and tested the system	Performed the experiments	Investigation	YES
5629616	28984193	GS	2	conceived the idea and designed the system|implemented and tested the system|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5629616	28984193	SZ	2	conceived the idea and designed the system|drafted the manuscript	conceived the idea and designed the system	Conceived and designed the experiments	Conceptualization	YES
5629616	28984193	SZ	2	conceived the idea and designed the system|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5733364	29326731	CT	1	Experimental design|Experiments|Data analysis|Manuscript preparation|Manuscript modification	Experimental design	Conceived and designed the experiments	Methodology	YES
5733364	29326731	CT	1	Experimental design|Experiments|Data analysis|Manuscript preparation|Manuscript modification	Experiments	-	-	NO
5733364	29326731	CT	1	Experimental design|Experiments|Data analysis|Manuscript preparation|Manuscript modification	Data analysis	Analyzed the data	Formal analysis	YES
5733364	29326731	CT	1	Experimental design|Experiments|Data analysis|Manuscript preparation|Manuscript modification	Manuscript preparation	Wrote the paper	Writing - Original Draft	YES
5733364	29326731	CT	1	Experimental design|Experiments|Data analysis|Manuscript preparation|Manuscript modification	Manuscript modification	Wrote the paper	Writing - Review & Editing	YES
5733364	29326731	DD	1	Experimental design	Experimental design	Conceived and designed the experiments	Methodology	YES
5733364	29326731	GS	1	Manuscript modification	Manuscript modification	Wrote the paper	Writing - Review & Editing	YES
5733364	29326731	LX	1	Manuscript modification	Manuscript modification	Wrote the paper	Writing - Review & Editing	YES
5733364	29326731	QY	1	Manuscript modification	Manuscript modification	Wrote the paper	Writing - Review & Editing	YES
5733364	29326731	ZZ	1	Data analysis	Data analysis	Analyzed the data	Formal analysis	YES
4414565	25923345	AF	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4414565	25923345	AF	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4414565	25923345	AF	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414565	25923345	AS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414565	25923345	AS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414565	25923345	AS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414565	25923345	BS	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414565	25923345	BS	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4414565	25923345	CB	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4414565	25923345	CQ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4414565	25923345	DFC	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4414565	25923345	ET	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414565	25923345	JD	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414565	25923345	JD	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414565	25923345	JD	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414565	25923345	JO	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414565	25923345	JO	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414565	25923345	JO	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414565	25923345	JT	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414565	25923345	ML	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414565	25923345	YS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4414565	25923345	YS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1910613	17637845	BG	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1910613	17637845	CO	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1910613	17637845	DE	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1910613	17637845	JM	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Wrote the paper|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1910613	17637845	JM	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Wrote the paper|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1910613	17637845	JM	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Wrote the paper|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1910613	17637845	JM	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Wrote the paper|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1910613	17637845	JM	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Wrote the paper|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1910613	17637845	JM	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Wrote the paper|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1910613	17637845	JM	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Wrote the paper|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1910613	17637845	JM	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Wrote the paper|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1910613	17637845	KT	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1910613	17637845	LC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1910613	17637845	LC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1910613	17637845	LC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1910613	17637845	LC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1910613	17637845	LO	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1910613	17637845	PF	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1910613	17637845	PF	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1910613	17637845	TK	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
6301908	30574662	AC	PLoS52	performed the experiments|conceived either all or parts of the study	performed the experiments	Performed the experiments	Investigation	YES
6301908	30574662	AC	PLoS52	performed the experiments|conceived either all or parts of the study	conceived either all or parts of the study	Conceived and designed the experiments	Conceptualization	YES
6301908	30574662	All authors	PLoS52	read, contributed to, and approved the final manuscript	read, contributed to, and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6301908	30574662	BC	PLoS52	wrote the paper|conceived either all or parts of the study	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6301908	30574662	BC	PLoS52	wrote the paper|conceived either all or parts of the study	conceived either all or parts of the study	Conceived and designed the experiments	Conceptualization	YES
6301908	30574662	CD	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
6301908	30574662	ED	PLoS52	performed the experiments|conceived either all or parts of the study	performed the experiments	Performed the experiments	Investigation	YES
6301908	30574662	ED	PLoS52	performed the experiments|conceived either all or parts of the study	conceived either all or parts of the study	Conceived and designed the experiments	Conceptualization	YES
6301908	30574662	MG	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
6301908	30574662	PSB	PLoS52	performed the experiments|wrote the paper|conceived either all or parts of the study	performed the experiments	Performed the experiments	Investigation	YES
6301908	30574662	PSB	PLoS52	performed the experiments|wrote the paper|conceived either all or parts of the study	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6301908	30574662	PSB	PLoS52	performed the experiments|wrote the paper|conceived either all or parts of the study	conceived either all or parts of the study	Conceived and designed the experiments	Conceptualization	YES
6301908	30574662	PW	PLoS52	conceived either all or parts of the study	conceived either all or parts of the study	Conceived and designed the experiments	Conceptualization	YES
6301908	30574662	RD	PLoS52	wrote the paper|conceived either all or parts of the study	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6301908	30574662	RD	PLoS52	wrote the paper|conceived either all or parts of the study	conceived either all or parts of the study	Conceived and designed the experiments	Conceptualization	YES
5050174	27704470	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5050174	27704470	HH	2	conducted experiments	conducted experiments	Performed the experiments	Investigation	YES
5050174	27704470	KK	2	designed the study|analyzed data|co-wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5050174	27704470	KK	2	designed the study|analyzed data|co-wrote the manuscript	analyzed data	Analyzed the data	Formal analysis	YES
5050174	27704470	KK	2	designed the study|analyzed data|co-wrote the manuscript	co-wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5050174	27704470	MU	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5050174	27704470	RI	2	designed the study|conducted experiments|analyzed data|co-wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5050174	27704470	RI	2	designed the study|conducted experiments|analyzed data|co-wrote the manuscript	conducted experiments	Performed the experiments	Investigation	YES
5050174	27704470	RI	2	designed the study|conducted experiments|analyzed data|co-wrote the manuscript	analyzed data	Analyzed the data	Formal analysis	YES
5050174	27704470	RI	2	designed the study|conducted experiments|analyzed data|co-wrote the manuscript	co-wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5050174	27704470	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5629617	28984204	ADR	PLoS52	conceived the project idea|wrote the manuscript	conceived the project idea	Conceived and designed the experiments	Conceptualization	YES
5629617	28984204	ADR	PLoS52	conceived the project idea|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5629617	28984204	JL	PLoS52	analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5629617	28984204	JL	PLoS52	analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5629617	28984204	LY	PLoS52	implemented the algorithm|analyzed the data|wrote the manuscript	implemented the algorithm	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5629617	28984204	LY	PLoS52	implemented the algorithm|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5629617	28984204	LY	PLoS52	implemented the algorithm|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5629617	28984204	QL	PLoS52	conceived the project idea|wrote the manuscript	conceived the project idea	Conceived and designed the experiments	Conceptualization	YES
5629617	28984204	QL	PLoS52	conceived the project idea|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5629617	28984204	XW	PLoS52	conceived the project idea|implemented the algorithm|analyzed the data|wrote the manuscript	conceived the project idea	Conceived and designed the experiments	Conceptualization	YES
5629617	28984204	XW	PLoS52	conceived the project idea|implemented the algorithm|analyzed the data|wrote the manuscript	implemented the algorithm	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5629617	28984204	XW	PLoS52	conceived the project idea|implemented the algorithm|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5629617	28984204	XW	PLoS52	conceived the project idea|implemented the algorithm|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5629617	28984204	all authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4414566	25922937	AK	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414566	25922937	AK	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414566	25922937	AS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414566	25922937	AS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414566	25922937	AS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414566	25922937	AS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414566	25922937	EL	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414566	25922937	EL	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4414566	25922937	EL	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414566	25922937	LK	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414566	25922937	LK	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414566	25922937	LM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414566	25922937	LM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4414566	25922937	LM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414566	25922937	M. Laine	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414566	25922937	M. Laine	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414566	25922937	M. Laine	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414566	25922937	M. Lehtonen	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414566	25922937	M. Lehtonen	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414566	25922937	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414566	25922937	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4414566	25922937	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414566	25922937	PR	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414566	25922937	PR	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414566	25922937	SD	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414566	25922937	SD	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4414566	25922937	SD	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1910614	17637846	AR	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1910614	17637846	CC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1910614	17637846	CG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1910614	17637846	DW	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1910614	17637846	DW	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1910614	17637846	EB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1910614	17637846	EB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1910614	17637846	EB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1910614	17637846	EC	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1910614	17637846	EC	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1910614	17637846	EM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1910614	17637846	EM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1910614	17637846	EM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1910614	17637846	EM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1910614	17637846	IM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1910614	17637846	IM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1910614	17637846	IM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6306370	30588554	CC	2	contributed greatly to the design of the study and global revision of the manuscript, including reviewing the choice of references, tables, and figures and editing the initial and every subsequent draft	contributed greatly to the design of the study and global revision of the manuscript, including reviewing the choice of references, tables, and figures and editing the initial and every subsequent draft	Conceived and designed the experiments|Wrote the paper	Methodology|Visualization|Writing - Original Draft|Writing - Review & Editing	YES
6306370	30588554	DO	2	contributed extensively to the design of the study, tracer synthesis, and data acquisition and analysis of the micropet data	contributed extensively to the design of the study, tracer synthesis, and data acquisition and analysis of the micropet data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Methodology|Resources	YES
6306370	30588554	FRAL	2	contributed greatly to the design of the study and global revision of the manuscript, including reviewing the choice of references, tables, and figures and editing the initial and every subsequent draft	contributed greatly to the design of the study and global revision of the manuscript, including reviewing the choice of references, tables, and figures and editing the initial and every subsequent draft	Conceived and designed the experiments|Wrote the paper	Methodology|Visualization|Writing - Original Draft|Writing - Review & Editing	YES
6306370	30588554	GB	2	contributed greatly to the design of the study and global revision of the manuscript, including reviewing the choice of references, tables, and figures and editing the initial and every subsequent draft	contributed greatly to the design of the study and global revision of the manuscript, including reviewing the choice of references, tables, and figures and editing the initial and every subsequent draft	Conceived and designed the experiments|Wrote the paper	Methodology|Visualization|Writing - Original Draft|Writing - Review & Editing	YES
6306370	30588554	IFV	2	jointly developed the concept of the manuscript, performed data analysis, and were highly involved in the writing of the manuscript	jointly developed the concept of the manuscript, performed data analysis, and were highly involved in the writing of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
6306370	30588554	KVL	2	contributed greatly to the design of the study and global revision of the manuscript, including reviewing the choice of references, tables, and figures and editing the initial and every subsequent draft	contributed greatly to the design of the study and global revision of the manuscript, including reviewing the choice of references, tables, and figures and editing the initial and every subsequent draft	Conceived and designed the experiments|Wrote the paper	Methodology|Visualization|Writing - Original Draft|Writing - Review & Editing	YES
6306370	30588554	MK	2	jointly developed the concept of the manuscript, performed data analysis, and were highly involved in the writing of the manuscript	jointly developed the concept of the manuscript, performed data analysis, and were highly involved in the writing of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
4609783	26509152	All authors	2	discussed the results and approved the final paper	discussed the results and approved the final paper	-	-	NO
4609783	26509152	Kazuo Hattori	2	contributed to the study design, data collection, data analysis, and paper preparation	contributed to the study design, data collection, data analysis, and paper preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Methodology|Resources	YES
4609783	26509152	Kentaro Imagawa	2	contributed to the study design, data collection, data analysis, and paper preparation	contributed to the study design, data collection, data analysis, and paper preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Methodology|Resources	YES
4609783	26509152	Nobuyasu Komasawa	2	contributed to the study design, study implementation, data analysis, and paper preparation	contributed to the study design, study implementation, data analysis, and paper preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Methodology|Resources	YES
4609783	26509152	Ryosuke Mihara	2	contributed to the study design, study implementation, data analysis, and paper preparation	contributed to the study design, study implementation, data analysis, and paper preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Methodology|Resources	YES
4609783	26509152	Toshiaki Minami	2	contributed to the study design and paper preparation	contributed to the study design and paper preparation	Conceived and designed the experiments	Methodology	YES
5633883	29017490	AB	2	performed necropsy and histopathological examinations	performed necropsy and histopathological examinations	Performed the experiments	Investigation	YES
5633883	29017490	CS	2	performed data collection and recorded the phenotypes	performed data collection and recorded the phenotypes	Performed the experiments	Investigation	YES
5633883	29017490	DE	2	performed necropsy and histopathological examinations	performed necropsy and histopathological examinations	Performed the experiments	Investigation	YES
5633883	29017490	HM	2	performed data collection and recorded the phenotypes	performed data collection and recorded the phenotypes	Performed the experiments	Investigation	YES
5633883	29017490	JM	2	designed the study, carried out the experiments and data analysis, drafted and finalized the manuscript	designed the study, carried out the experiments and data analysis, drafted and finalized the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5633883	29017490	KF	2	performed clinical examinations and computed tomography	performed clinical examinations and computed tomography	Performed the experiments	Formal analysis|Investigation	YES
5633883	29017490	MH	2	performed clinical examinations and computed tomography	performed clinical examinations and computed tomography	Performed the experiments	Formal analysis|Investigation	YES
5633883	29017490	OD	2	designed the study, carried out the experiments and data analysis, drafted and finalized the manuscript	designed the study, carried out the experiments and data analysis, drafted and finalized the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5633883	29017490	SR	2	designed the study, carried out the experiments and data analysis, drafted and finalized the manuscript|performed clinical examinations and computed tomography	designed the study, carried out the experiments and data analysis, drafted and finalized the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5633883	29017490	SR	2	designed the study, carried out the experiments and data analysis, drafted and finalized the manuscript|performed clinical examinations and computed tomography	performed clinical examinations and computed tomography	Performed the experiments	Formal analysis|Investigation	YES
5733471	29326733	All authors	2	reviewed and approved the final manuscript	reviewed and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5733471	29326733	FX	2	grew the cotton seedlings and performed the physiological experiments|analyzed the physiological and proteome results and prepared the manuscript	grew the cotton seedlings and performed the physiological experiments	Performed the experiments	Investigation	YES
5733471	29326733	FX	2	grew the cotton seedlings and performed the physiological experiments|analyzed the physiological and proteome results and prepared the manuscript	analyzed the physiological and proteome results and prepared the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5733471	29326733	JS	2	participated in the management of cotton cultivation	participated in the management of cotton cultivation	-	-	NO
5733471	29326733	SH	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5733471	29326733	WG	2	designed the experiment|analyzed the physiological and proteome results and prepared the manuscript	designed the experiment	Conceived and designed the experiments	Methodology	YES
5733471	29326733	WG	2	designed the experiment|analyzed the physiological and proteome results and prepared the manuscript	analyzed the physiological and proteome results and prepared the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5733471	29326733	XD	2	received grant support|designed the experiment|revised the manuscript	received grant support	-	Funding acquisition	YES
5733471	29326733	XD	2	received grant support|designed the experiment|revised the manuscript	designed the experiment	Conceived and designed the experiments	Methodology	YES
5733471	29326733	XD	2	received grant support|designed the experiment|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5733471	29326733	ZP	2	participated in the management of cotton cultivation|revised the manuscript	participated in the management of cotton cultivation	-	-	NO
5733471	29326733	ZP	2	participated in the management of cotton cultivation|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4414567	25923670	BHT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414567	25923670	BHT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414567	25923670	BHT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414567	25923670	BHT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414567	25923670	BHT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414567	25923670	BZP	PLoS5	Contributed reagents/materials/analysis tools|Contributed to revising the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414567	25923670	BZP	PLoS5	Contributed reagents/materials/analysis tools|Contributed to revising the manuscript	Contributed to revising the manuscript	Wrote the paper	Writing - Review & Editing	YES
4414567	25923670	CS	PLoS5	Conceived and designed the experiments|Contributed to revising the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414567	25923670	CS	PLoS5	Conceived and designed the experiments|Contributed to revising the manuscript	Contributed to revising the manuscript	Wrote the paper	Writing - Review & Editing	YES
4414567	25923670	DJT	PLoS5	Analyzed the data|Contributed to revising the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4414567	25923670	DJT	PLoS5	Analyzed the data|Contributed to revising the manuscript	Contributed to revising the manuscript	Wrote the paper	Writing - Review & Editing	YES
4414567	25923670	JCM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Contributed to revising the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414567	25923670	JCM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Contributed to revising the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414567	25923670	JCM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Contributed to revising the manuscript	Contributed to revising the manuscript	Wrote the paper	Writing - Review & Editing	YES
4414567	25923670	MJA	PLoS5	Contributed reagents/materials/analysis tools|Contributed to revising the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414567	25923670	MJA	PLoS5	Contributed reagents/materials/analysis tools|Contributed to revising the manuscript	Contributed to revising the manuscript	Wrote the paper	Writing - Review & Editing	YES
4414567	25923670	RMH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414567	25923670	RMH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414567	25923670	RMH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414567	25923670	SD	PLoS5	Contributed reagents/materials/analysis tools|Contributed to revising the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414567	25923670	SD	PLoS5	Contributed reagents/materials/analysis tools|Contributed to revising the manuscript	Contributed to revising the manuscript	Wrote the paper	Writing - Review & Editing	YES
4414567	25923670	YH	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414567	25923670	YH	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1913202	17637840	AW	PLoS5	Wrote the paper|Conceived and designed the model|Interpretation of the results|Performed the computer simulations	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1913202	17637840	AW	PLoS5	Wrote the paper|Conceived and designed the model|Interpretation of the results|Performed the computer simulations	Conceived and designed the model	Conceived and designed the experiments|Performed the experiments	Conceptualization|Methodology	YES
1913202	17637840	AW	PLoS5	Wrote the paper|Conceived and designed the model|Interpretation of the results|Performed the computer simulations	Interpretation of the results	Analyzed the data	Formal analysis	YES
1913202	17637840	AW	PLoS5	Wrote the paper|Conceived and designed the model|Interpretation of the results|Performed the computer simulations	Performed the computer simulations	Performed the experiments	Formal analysis|Investigation	YES
1913202	17637840	KW	PLoS5	Wrote the paper|Interpretation of the results	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1913202	17637840	KW	PLoS5	Wrote the paper|Interpretation of the results	Interpretation of the results	Analyzed the data	Formal analysis	YES
1913202	17637840	MB	PLoS5	Wrote the paper|Conceived and designed the model|Interpretation of the results	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1913202	17637840	MB	PLoS5	Wrote the paper|Conceived and designed the model|Interpretation of the results	Conceived and designed the model	Conceived and designed the experiments|Performed the experiments	Conceptualization|Methodology	YES
1913202	17637840	MB	PLoS5	Wrote the paper|Conceived and designed the model|Interpretation of the results	Interpretation of the results	Analyzed the data	Formal analysis	YES
1913202	17637840	MM	PLoS5	Analyzed the data|Wrote the paper|Conceived and designed the model|Interpretation of the results|Performed the computer simulations	Analyzed the data	Analyzed the data	Formal analysis	YES
1913202	17637840	MM	PLoS5	Analyzed the data|Wrote the paper|Conceived and designed the model|Interpretation of the results|Performed the computer simulations	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1913202	17637840	MM	PLoS5	Analyzed the data|Wrote the paper|Conceived and designed the model|Interpretation of the results|Performed the computer simulations	Conceived and designed the model	Conceived and designed the experiments|Performed the experiments	Conceptualization|Methodology	YES
1913202	17637840	MM	PLoS5	Analyzed the data|Wrote the paper|Conceived and designed the model|Interpretation of the results|Performed the computer simulations	Interpretation of the results	Analyzed the data	Formal analysis	YES
1913202	17637840	MM	PLoS5	Analyzed the data|Wrote the paper|Conceived and designed the model|Interpretation of the results|Performed the computer simulations	Performed the computer simulations	Performed the experiments	Formal analysis|Investigation	YES
5050181	27704471	AC	1	Planning and designing of study	Planning and designing of study	Conceived and designed the experiments	Methodology	YES
5050181	27704471	MA	1	Planning and designing of study	Planning and designing of study	Conceived and designed the experiments	Methodology	YES
6306373	30588560	CH	2	designed the study, contributed to data interpretation, and were a major contributor in drafting and revising the manuscript	designed the study, contributed to data interpretation, and were a major contributor in drafting and revising the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
6306373	30588560	JB	2	generated the in vitro binding data, drafted and revised the manuscript	generated the in vitro binding data, drafted and revised the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
6306373	30588560	LF	2	contributed to the design of the study, interpretation of the data, drafted and revised the manuscript	contributed to the design of the study, interpretation of the data, drafted and revised the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
6306373	30588560	LJ	2	contributed to the design of the study, interpretation of the data, drafted and revised the manuscript	contributed to the design of the study, interpretation of the data, drafted and revised the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
6306373	30588560	LK	2	performed the tritium labeling, drafted and revised the manuscript	performed the tritium labeling, drafted and revised the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
6306373	30588560	MJ	2	designed the study, performed the experiments, acquired the data, contributed to data analysis and interpretation of the data, and were a major contributor in drafting and revising the manuscript	designed the study, performed the experiments, acquired the data, contributed to data analysis and interpretation of the data, and were a major contributor in drafting and revising the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
6306373	30588560	MSW	2	generated the in vitro binding data, drafted and revised the manuscript	generated the in vitro binding data, drafted and revised the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
6306373	30588560	Magnus Schou	2	contributed to the design of the study, interpretation of the data, drafted and revised the manuscript	contributed to the design of the study, interpretation of the data, drafted and revised the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
6306373	30588560	Marie Svedberg	2	generated autoradiography, homogenate binding and ich data, drafted and revised the manuscript	generated autoradiography, homogenate binding and ich data, drafted and revised the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
6306373	30588560	OE	2	designed the study, performed the experiments, acquired the data, contributed to data analysis and interpretation of the data, and were a major contributor in drafting and revising the manuscript	designed the study, performed the experiments, acquired the data, contributed to data analysis and interpretation of the data, and were a major contributor in drafting and revising the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
6306373	30588560	OK	2	contributed to the design of the study, interpretation of the data, drafted and revised the manuscript	contributed to the design of the study, interpretation of the data, drafted and revised the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
6306373	30588560	PJ	2	designed the study, contributed to data interpretation, and were a major contributor in drafting and revising the manuscript	designed the study, contributed to data interpretation, and were a major contributor in drafting and revising the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
6306373	30588560	RKS	2	generated autoradiography, homogenate binding and ich data, drafted and revised the manuscript	generated autoradiography, homogenate binding and ich data, drafted and revised the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
6306373	30588560	SS	2	contributed to the design of the study, interpretation of the data, drafted and revised the manuscript	contributed to the design of the study, interpretation of the data, drafted and revised the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
6306373	30588560	ZJ	2	performed the tritium labeling, drafted and revised the manuscript	performed the tritium labeling, drafted and revised the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
1913203	17637841	FK	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1913203	17637841	FK	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1913203	17637841	SF	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1913203	17637841	SF	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1913203	17637841	SS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1913203	17637841	TE	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1913203	17637841	TE	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1913203	17637841	TE	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414568	25923213	AJWH	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414568	25923213	AJWH	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414568	25923213	ARW	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414568	25923213	ARW	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414568	25923213	CDG	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414568	25923213	CDG	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414568	25923213	JVJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414568	25923213	JVJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414568	25923213	JVJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414568	25923213	JVJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5635495	29017442	JS	PLoS52	conceived and designed the study|conducted the data analyses|performed the experiments|drafted and revised the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5635495	29017442	JS	PLoS52	conceived and designed the study|conducted the data analyses|performed the experiments|drafted and revised the manuscript	conducted the data analyses	Analyzed the data	Formal analysis	YES
5635495	29017442	JS	PLoS52	conceived and designed the study|conducted the data analyses|performed the experiments|drafted and revised the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5635495	29017442	JS	PLoS52	conceived and designed the study|conducted the data analyses|performed the experiments|drafted and revised the manuscript	drafted and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5635495	29017442	JW	PLoS52	conceived and designed the study|drafted and revised the manuscript|supervised the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5635495	29017442	JW	PLoS52	conceived and designed the study|drafted and revised the manuscript|supervised the study	drafted and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5635495	29017442	JW	PLoS52	conceived and designed the study|drafted and revised the manuscript|supervised the study	supervised the study	-	Supervision	YES
5635495	29017442	LL	PLoS52	conceived and designed the study|conducted the data analyses|drafted and revised the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5635495	29017442	LL	PLoS52	conceived and designed the study|conducted the data analyses|drafted and revised the manuscript	conducted the data analyses	Analyzed the data	Formal analysis	YES
5635495	29017442	LL	PLoS52	conceived and designed the study|conducted the data analyses|drafted and revised the manuscript	drafted and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5635495	29017442	PW	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5635495	29017442	SZ	PLoS52	supervised the study	supervised the study	-	Supervision	YES
5733493	29326740	AA	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5733493	29326740	FW	2	designed some of the experiments	designed some of the experiments	Conceived and designed the experiments	Methodology	YES
5733493	29326740	JW	2	designed some of the experiments	designed some of the experiments	Conceived and designed the experiments	Methodology	YES
5733493	29326740	KZ	2	conceived and designed the research|wrote the manuscript	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5733493	29326740	KZ	2	conceived and designed the research|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5733493	29326740	TCK-EGGE	2	its transgenic plants	its transgenic plants	Performed the experiments	Investigation	YES
5733493	29326740	TCK-RGGR	2	its transgenic plants	its transgenic plants	Performed the experiments	Investigation	YES
4609785	26509161	Chien-Yih Lin	2	contributed to the design and conception of the study and interpretation of data	contributed to the design and conception of the study and interpretation of data	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Methodology|Resources	YES
4609785	26509161	Marcelia Sugata	2	carried out the study and prepared the paper|contributed to the design and conception of the study and interpretation of data	carried out the study and prepared the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4609785	26509161	Marcelia Sugata	2	carried out the study and prepared the paper|contributed to the design and conception of the study and interpretation of data	contributed to the design and conception of the study and interpretation of data	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Methodology|Resources	YES
4609785	26509161	Yang-Chia Shih	2	contributed to the design and conception of the study and interpretation of data|critically revised the paper	contributed to the design and conception of the study and interpretation of data	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Methodology|Resources	YES
4609785	26509161	Yang-Chia Shih	2	contributed to the design and conception of the study and interpretation of data|critically revised the paper	critically revised the paper	Wrote the paper	Writing - Review & Editing	YES
5052237	27709547	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5052237	27709547	All three authors	2	interpreted data and edited the manuscript	interpreted data and edited the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5052237	27709547	Biological Engineering Department	2	for support	for support	-	-	NO
5052237	27709547	Gary Strobel	2	for sound technical advice	for sound technical advice	-	-	NO
5052237	27709547	HRS	2	performed experiments and drafted the manuscript	performed experiments and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5052237	27709547	Natasha Mallette	2	for sound technical advice	for sound technical advice	-	-	NO
5052237	27709547	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5052237	27709547	WBK	2	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
6311169	30594961	CBF	2	performed the immunohistochemically analyses	performed the immunohistochemically analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6311169	30594961	CLa	2	performed the statistical analysis, wrote the article and built figures and tables	performed the statistical analysis, wrote the article and built figures and tables	Analyzed the data|Wrote the paper	Formal analysis|Visualization|Writing - Original Draft	YES
6311169	30594961	CLe	2	included the patients	included the patients	-	-	NO
6311169	30594961	CT	2	images analysis and helped writing the manuscript	images analysis and helped writing the manuscript	Analyzed the data|Wrote the paper	Visualization|Writing - Original Draft	YES
6311169	30594961	JMG	2	collected the clinical data	collected the clinical data	Performed the experiments	Investigation	YES
6311169	30594961	NA	2	designed the study and provided critical readings of the manuscript	designed the study and provided critical readings of the manuscript	Conceived and designed the experiments	Methodology	YES
1913204	17637830	BN	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1913204	17637830	BN	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1913204	17637830	CM	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1913204	17637830	CM	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1913204	17637830	IP	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1913204	17637830	IP	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1913204	17637830	IP	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1913204	17637830	NB	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1913204	17637830	NB	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1913204	17637830	PT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1913204	17637830	PT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1913204	17637830	PT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1913204	17637830	PT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1913204	17637830	PT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414569	25923116	CGP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414569	25923116	CGP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414569	25923116	CGP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414569	25923116	CTTB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414569	25923116	CTTB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414569	25923116	CTTB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414569	25923116	CTTB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414569	25923116	JFG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414569	25923116	JFG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414569	25923116	JFG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414569	25923116	JJK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414569	25923116	JJK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414569	25923116	JJK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414569	25923116	JJK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414569	25923116	KAG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414569	25923116	KAG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414569	25923116	KAG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414569	25923116	TT	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414569	25923116	TT	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5635513	29017458	AAF	PLoS52	prepared the biological samples and libraries|analyzed the data	prepared the biological samples and libraries	Performed the experiments	Investigation	YES
5635513	29017458	AAF	PLoS52	prepared the biological samples and libraries|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5635513	29017458	HSJ	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5635513	29017458	JS	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5733502	29326737	CF	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5733502	29326737	CF	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5733502	29326737	CX	PLoS52	conceived and designed the experiment|contributed regents/material/analysis tools	conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5733502	29326737	CX	PLoS52	conceived and designed the experiment|contributed regents/material/analysis tools	contributed regents/material/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5733502	29326737	GZ	PLoS52	performed the experiments|analyzed the data|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5733502	29326737	GZ	PLoS52	performed the experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5733502	29326737	GZ	PLoS52	performed the experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5733502	29326737	SD	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5733502	29326737	SD	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5733502	29326737	XW	PLoS52	conceived and designed the experiment|contributed regents/material/analysis tools	conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5733502	29326737	XW	PLoS52	conceived and designed the experiment|contributed regents/material/analysis tools	contributed regents/material/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5733502	29326737	YP	PLoS52	conceived and designed the experiment|analyzed the data|contributed regents/material/analysis tools|wrote the paper	conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5733502	29326737	YP	PLoS52	conceived and designed the experiment|analyzed the data|contributed regents/material/analysis tools|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5733502	29326737	YP	PLoS52	conceived and designed the experiment|analyzed the data|contributed regents/material/analysis tools|wrote the paper	contributed regents/material/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5733502	29326737	YP	PLoS52	conceived and designed the experiment|analyzed the data|contributed regents/material/analysis tools|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
1913205	17637842	AW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1913205	17637842	AW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1913205	17637842	AW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1913205	17637842	AW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1913205	17637842	FR	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1913205	17637842	FR	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1913205	17637842	FR	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1913205	17637842	IM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1913205	17637842	IM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1913205	17637842	IM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1913205	17637842	IM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1913205	17637842	IM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1913205	17637842	MI	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1913205	17637842	MI	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1913205	17637842	MI	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6318156	30607646	CHW	2	were involved in data collection	were involved in data collection	Performed the experiments	Investigation	YES
6318156	30607646	CTW	2	were involved in data collection	were involved in data collection	Performed the experiments	Investigation	YES
6318156	30607646	ITH	2	contributed to image analysis	contributed to image analysis	Analyzed the data	Visualization	YES
6318156	30607646	JRT	2	participated in the study design and drafted the manuscript	participated in the study design and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
6318156	30607646	LYY	2	was in charge of data analysis	was in charge of data analysis	Analyzed the data	Formal analysis	YES
6318156	30607646	SYC	2	were involved in data collection	were involved in data collection	Performed the experiments	Investigation	YES
6318156	30607646	TCY	2	participated in the study design and drafted the manuscript	participated in the study design and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
6318156	30607646	YHC	2	participated in the study design and drafted the manuscript	participated in the study design and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5053951	27714704	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5053951	27714704	LD	2	performed the nasba-elisa, all of data analysis and wrote the manuscript	performed the nasba-elisa, all of data analysis and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5053951	27714704	YH	2	corrected the manuscript	corrected the manuscript	Wrote the paper	Writing - Review & Editing	YES
5053951	27714704	YX	2	designed the study and supervised all the experiments	designed the study and supervised all the experiments	Conceived and designed the experiments	Methodology|Supervision	YES
5997593	29189960	All	5	named authors meet the international committee of Medical Journal Editors (icmje) criteria for authorship for this manuscript	named authors meet the international committee of Medical Journal Editors (icmje) criteria for authorship for this manuscript	Wrote the paper	Writing - Review & Editing	YES
4414570	25923211	AC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414570	25923211	AC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414570	25923211	AC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414570	25923211	AC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414570	25923211	AC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414570	25923211	FF	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414570	25923211	FF	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414570	25923211	FF	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414570	25923211	LC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414570	25923211	LC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414570	25923211	LC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414570	25923211	LC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414570	25923211	LC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414570	25923211	MA	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414570	25923211	MA	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414570	25923211	MH	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5635574	29017450	GZ	2	designed the experiments, did the data analysis and wrote the manuscript	designed the experiments, did the data analysis and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5635574	29017450	HP	2	did the clsm and rt pcr	did the clsm and rt pcr	Performed the experiments	Investigation	YES
5635574	29017450	QSS	2	designed the experiments, did the data analysis and wrote the manuscript	designed the experiments, did the data analysis and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5635574	29017450	XBX	2	helped the data analysis and contributed to manuscript writing and revision	helped the data analysis and contributed to manuscript writing and revision	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5635574	29017450	XMH	2	helped the data analysis and contributed to manuscript writing and revision	helped the data analysis and contributed to manuscript writing and revision	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5635574	29017450	YSW	2	did the clsm and rt pcr	did the clsm and rt pcr	Performed the experiments	Investigation	YES
1913206	17637834	MB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1913206	17637834	MB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1913206	17637834	MB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1913206	17637834	PT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1913206	17637834	PT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1913206	17637834	PT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1913206	17637834	PT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1913206	17637834	SO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1913206	17637834	SO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1913206	17637834	SO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1913206	17637834	YH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1913206	17637834	YH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1913206	17637834	YH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1913206	17637834	YH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5733541	29321792	GS	2	contributed equally to the discussion of the topic	contributed equally to the discussion of the topic	-	-	NO
5733541	29321792	MdA	2	contributed equally to the discussion of the topic	contributed equally to the discussion of the topic	-	-	NO
5055507	27718214	AAB	2	contributed data analysis	contributed data analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5055507	27718214	AHE	2	designed research	designed research	Conceived and designed the experiments	Methodology	YES
5055507	27718214	All authors	2	were involved in data interpretation and the writing of the paper|read and approved the final manuscript	were involved in data interpretation and the writing of the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5055507	27718214	All authors	2	were involved in data interpretation and the writing of the paper|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5055507	27718214	GDG	2	designed research	designed research	Conceived and designed the experiments	Methodology	YES
5055507	27718214	MAVL	2	contributed data analysis	contributed data analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5055507	27718214	MBM	2	designed research	designed research	Conceived and designed the experiments	Methodology	YES
5055507	27718214	MTT	2	preformed all experiments	preformed all experiments	Performed the experiments	Investigation	YES
5055507	27718214	SNG	2	preformed all experiments	preformed all experiments	Performed the experiments	Investigation	YES
5055507	27718214	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5055507	27718214	VGB	2	preformed all experiments	preformed all experiments	Performed the experiments	Investigation	YES
1913207	17637844	CN	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1913207	17637844	CN	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1913207	17637844	CN	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1913207	17637844	MD	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1913207	17637844	RH	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1913207	17637844	RH	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1913207	17637844	ST	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1913207	17637844	WD	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1913207	17637844	XC	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1913207	17637844	YL	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1913207	17637844	YL	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1913207	17637844	YW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4414571	25923432	EM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414571	25923432	EM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414571	25923432	EM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414571	25923432	EM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414571	25923432	ER	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4414571	25923432	ER	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4414571	25923432	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414571	25923432	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414571	25923432	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414571	25923432	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414571	25923432	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414571	25923432	MK	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4414571	25923432	MK	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4414571	25923432	NND	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414571	25923432	NND	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414571	25923432	NND	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414571	25923432	NND	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414571	25923432	SJS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414571	25923432	SJS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414571	25923432	TH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4414571	25923432	TH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4414571	25923432	TH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
6318161	30607651	AM	2	contributed to the data processing and manuscript revision	contributed to the data processing and manuscript revision	Analyzed the data|Wrote the paper	Data curation|Writing - Review & Editing	YES
6318161	30607651	DM	2	contributed to the study design, data interpretation and manuscript revision	contributed to the study design, data interpretation and manuscript revision	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Review & Editing	YES
6318161	30607651	KB	2	contributed to the data interpretation and manuscript revision	contributed to the data interpretation and manuscript revision	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
6318161	30607651	MW	2	contributed to the study design and data acquisition	contributed to the study design and data acquisition	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources	YES
5733556	29321790	HJ	PLoS5	Generated the data and performed the analysis	Generated the data and performed the analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5733556	29321790	HL	PLoS5	Generated the data and performed the analysis	Generated the data and performed the analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5733556	29321790	LS	PLoS5	Conceived and designed the study|Generated the data and performed the analysis|Wrote the paper	Conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5733556	29321790	LS	PLoS5	Conceived and designed the study|Generated the data and performed the analysis|Wrote the paper	Generated the data and performed the analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5733556	29321790	LS	PLoS5	Conceived and designed the study|Generated the data and performed the analysis|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5733556	29321790	SY	PLoS5	Contributed reagents, materials, analysis tools	Contributed reagents, materials, analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5733556	29321790	ZC	PLoS5	Generated the data and performed the analysis	Generated the data and performed the analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5733556	29321790	ZD	PLoS5	Generated the data and performed the analysis|Wrote the paper	Generated the data and performed the analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5733556	29321790	ZD	PLoS5	Generated the data and performed the analysis|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5733556	29321790	ZY	PLoS5	Contributed reagents, materials, analysis tools	Contributed reagents, materials, analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4609796	26509170	Chia-Chen Chuang	2	contributed to the work equally	contributed to the work equally	-	-	NO
4609796	26509170	Tingyang Zhou	2	contributed to the work equally	contributed to the work equally	-	-	NO
5637055	29020916	GW	2	participated in the data analysis and graphics	participated in the data analysis and graphics	Analyzed the data	Formal analysis	YES
5637055	29020916	GY	2	conducted animal experiments and surgical processes	conducted animal experiments and surgical processes	Performed the experiments	Investigation	YES
5637055	29020916	JBL	2	conducted animal experiments and surgical processes	conducted animal experiments and surgical processes	Performed the experiments	Investigation	YES
5637055	29020916	LZX	2	conducted qpcr validation	conducted qpcr validation	Performed the experiments	Investigation|Validation	YES
5637055	29020916	QL	2	provided the experimental animals	provided the experimental animals	-	-	NO
5637055	29020916	WSH	2	conceived the idea of this research, performed data analysis and drafted the manuscript	conceived the idea of this research, performed data analysis and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
5637055	29020916	WX	2	provided the experimental environment and coordination	provided the experimental environment and coordination	-	Project administration	YES
5637055	29020916	ZZY	2	provided the experimental environment and coordination	provided the experimental environment and coordination	-	Project administration	YES
1913551	17622341	AS	PLoS5	Performed the experiments|Assisted with the design of the radiation apparatus and the early radiation experiments	Performed the experiments	Performed the experiments	Investigation	YES
1913551	17622341	AS	PLoS5	Performed the experiments|Assisted with the design of the radiation apparatus and the early radiation experiments	Assisted with the design of the radiation apparatus and the early radiation experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
1913551	17622341	BC	PLoS5	Performed the experiments|Analyzed the data|Performed the majority of the radiation experiments, and the majority of the stereological analyses	Performed the experiments	Performed the experiments	Investigation	YES
1913551	17622341	BC	PLoS5	Performed the experiments|Analyzed the data|Performed the majority of the radiation experiments, and the majority of the stereological analyses	Analyzed the data	Analyzed the data	Formal analysis	YES
1913551	17622341	BC	PLoS5	Performed the experiments|Analyzed the data|Performed the majority of the radiation experiments, and the majority of the stereological analyses	Performed the majority of the radiation experiments, and the majority of the stereological analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
1913551	17622341	EG	PLoS5	Performed the experiments|Assisted with the radiation experiments and immunohistochemistry	Performed the experiments	Performed the experiments	Investigation	YES
1913551	17622341	EG	PLoS5	Performed the experiments|Assisted with the radiation experiments and immunohistochemistry	Assisted with the radiation experiments and immunohistochemistry	Performed the experiments	Investigation	YES
1913551	17622341	GA	PLoS5	Performed the experiments|Analyzed the data|Performed the majority of the human tissue immunohistochemical analyses, assisted with animal irradiation and care	Performed the experiments	Performed the experiments	Investigation	YES
1913551	17622341	GA	PLoS5	Performed the experiments|Analyzed the data|Performed the majority of the human tissue immunohistochemical analyses, assisted with animal irradiation and care	Analyzed the data	Analyzed the data	Formal analysis	YES
1913551	17622341	GA	PLoS5	Performed the experiments|Analyzed the data|Performed the majority of the human tissue immunohistochemical analyses, assisted with animal irradiation and care	Performed the majority of the human tissue immunohistochemical analyses, assisted with animal irradiation and care	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
1913551	17622341	GP	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Performed most of the tissue preparation and the majority of the experiments and data analysis, contributed significantly to the manuscript preparation and contributed to the supervision of all aspects of the study	Performed the experiments	Performed the experiments	Investigation	YES
1913551	17622341	GP	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Performed most of the tissue preparation and the majority of the experiments and data analysis, contributed significantly to the manuscript preparation and contributed to the supervision of all aspects of the study	Analyzed the data	Analyzed the data	Formal analysis	YES
1913551	17622341	GP	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Performed most of the tissue preparation and the majority of the experiments and data analysis, contributed significantly to the manuscript preparation and contributed to the supervision of all aspects of the study	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1913551	17622341	GP	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Performed most of the tissue preparation and the majority of the experiments and data analysis, contributed significantly to the manuscript preparation and contributed to the supervision of all aspects of the study	Performed most of the tissue preparation and the majority of the experiments and data analysis, contributed significantly to the manuscript preparation and contributed to the supervision of all aspects of the study	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Supervision|Writing - Original Draft	YES
1913551	17622341	MB	PLoS5	Performed the experiments|Performed the mri imaging and analyses	Performed the experiments	Performed the experiments	Investigation	YES
1913551	17622341	MB	PLoS5	Performed the experiments|Performed the mri imaging and analyses	Performed the mri imaging and analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
1913551	17622341	ME	PLoS5	Analyzed the data|Performed the histology and ultrastructural analyses	Analyzed the data	Analyzed the data	Formal analysis	YES
1913551	17622341	ME	PLoS5	Analyzed the data|Performed the histology and ultrastructural analyses	Performed the histology and ultrastructural analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
1913551	17622341	PG	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1913551	17622341	RA	PLoS5	Performed the experiments|Analyzed the data|Contributed to the immunohistochemistry and tissue preparation and performed the capillary analysis including stereology	Performed the experiments	Performed the experiments	Investigation	YES
1913551	17622341	RA	PLoS5	Performed the experiments|Analyzed the data|Contributed to the immunohistochemistry and tissue preparation and performed the capillary analysis including stereology	Analyzed the data	Analyzed the data	Formal analysis	YES
1913551	17622341	RA	PLoS5	Performed the experiments|Analyzed the data|Contributed to the immunohistochemistry and tissue preparation and performed the capillary analysis including stereology	Contributed to the immunohistochemistry and tissue preparation and performed the capillary analysis including stereology	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
1913551	17622341	VT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1913551	17622341	VT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1913551	17622341	VT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5055519	27718213	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5055519	27718213	All the authors	2	conceived the research work	conceived the research work	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5055519	27718213	SK	2	carried out the experiments and wrote the manuscript	carried out the experiments and wrote the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6323046	30617563	All authors	2	have reviewed and approved the final document	have reviewed and approved the final document	-	-	NO
6323046	30617563	DHM	2	takes full responsibility for the data, analyses and interpretation and the manner in which the research was conducted	takes full responsibility for the data, analyses and interpretation and the manner in which the research was conducted	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4414572	25923328	HELM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414572	25923328	HELM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414572	25923328	HELM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414572	25923328	HELM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414572	25923328	PDNH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414572	25923328	PDNH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414572	25923328	PDNH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414572	25923328	RAG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414572	25923328	RAG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414572	25923328	RAG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414572	25923328	RAG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414572	25923328	RAG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414572	25923328	RGF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414572	25923328	RGF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414572	25923328	RGF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414572	25923328	RGF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5997597	29725860	SLR	2	publication concept development, drafting, reviewing, and editing the manuscript	publication concept development, drafting, reviewing, and editing the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
5733559	29321791	H-XZ	7	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents, materials, analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5733559	29321791	H-XZ	7	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents, materials, analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
5733559	29321791	H-XZ	7	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents, materials, analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5733559	29321791	H-XZ	7	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents, materials, analysis tools|Wrote the paper	Contributed reagents, materials, analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5733559	29321791	H-XZ	7	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents, materials, analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5733559	29321791	M-LZ	7	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5733559	29321791	M-LZ	7	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5637070	29020919	CMW	2	carried out rna seq experiment and bioinformatics analysis|wrote the manuscript	carried out rna seq experiment and bioinformatics analysis	Performed the experiments	Formal analysis|Investigation	YES
5637070	29020919	CMW	2	carried out rna seq experiment and bioinformatics analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5637070	29020919	CN	2	conducted field trials	conducted field trials	Performed the experiments	Investigation	YES
5637070	29020919	JZ	2	carried out rna seq experiment and bioinformatics analysis	carried out rna seq experiment and bioinformatics analysis	Performed the experiments	Formal analysis|Investigation	YES
5637070	29020919	RM	2	conceived the study, coordinated all research activities|wrote the manuscript	conceived the study, coordinated all research activities	Conceived and designed the experiments	Conceptualization|Project administration	YES
5637070	29020919	RM	2	conceived the study, coordinated all research activities|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5637070	29020919	TJ	2	conducted field trials	conducted field trials	Performed the experiments	Investigation	YES
1913552	17637847	AT	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1913552	17637847	AT	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1913552	17637847	AT	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1913552	17637847	HK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1913552	17637847	HK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1913552	17637847	HK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1913552	17637847	HK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1913552	17637847	HK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1913552	17637847	MK	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1913552	17637847	MK	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1913552	17637847	ZF	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5055523	27718215	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5055523	27718215	HA	2	designed this study, performed experiments, participated in the interpretation of the results and drafted the manuscript	designed this study, performed experiments, participated in the interpretation of the results and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5055523	27718215	NN	2	participated in the design and coordination of this study and helped to revise the manuscript	participated in the design and coordination of this study and helped to revise the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Review & Editing	YES
5055523	27718215	TH	2	conceived and designed this study, coordinated the experiments, interpreted the results and revised the manuscript for important intellectual content	conceived and designed this study, coordinated the experiments, interpreted the results and revised the manuscript for important intellectual content	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Project administration|Writing - Review & Editing	YES
5055523	27718215	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
3844241	24348185	Guadalupe Alvarez-Hernan	2	contributed equally to this work	contributed equally to this work	-	-	NO
3844241	24348185	Ruth Bejarano-Escobar	2	contributed equally to this work	contributed equally to this work	-	-	NO
6335230	30649637	GN	2	contributed to the design and manuscript preparation|performed the clinical studies|performed the clinical follow up	contributed to the design and manuscript preparation	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
6335230	30649637	GN	2	contributed to the design and manuscript preparation|performed the clinical studies|performed the clinical follow up	performed the clinical studies	Performed the experiments	Investigation	YES
6335230	30649637	GN	2	contributed to the design and manuscript preparation|performed the clinical studies|performed the clinical follow up	performed the clinical follow up	Performed the experiments	Investigation	YES
6335230	30649637	HS	2	performed the clinical studies|performed the clinical follow up	performed the clinical studies	Performed the experiments	Investigation	YES
6335230	30649637	HS	2	performed the clinical studies|performed the clinical follow up	performed the clinical follow up	Performed the experiments	Investigation	YES
6335230	30649637	JT	2	contributed to the design and manuscript preparation	contributed to the design and manuscript preparation	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
6335230	30649637	KN	2	performed the clinical studies	performed the clinical studies	Performed the experiments	Investigation	YES
6335230	30649637	MH	2	contributed to the design and manuscript preparation|performed the clinical studies|performed the data analysis/interpretation	contributed to the design and manuscript preparation	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
6335230	30649637	MH	2	contributed to the design and manuscript preparation|performed the clinical studies|performed the data analysis/interpretation	performed the clinical studies	Performed the experiments	Investigation	YES
6335230	30649637	MH	2	contributed to the design and manuscript preparation|performed the clinical studies|performed the data analysis/interpretation	performed the data analysis/interpretation	Analyzed the data	Formal analysis	YES
6335230	30649637	RM	2	contributed to the design and manuscript preparation|performed the clinical studies|performed the data analysis/interpretation	contributed to the design and manuscript preparation	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
6335230	30649637	RM	2	contributed to the design and manuscript preparation|performed the clinical studies|performed the data analysis/interpretation	performed the clinical studies	Performed the experiments	Investigation	YES
6335230	30649637	RM	2	contributed to the design and manuscript preparation|performed the clinical studies|performed the data analysis/interpretation	performed the data analysis/interpretation	Analyzed the data	Formal analysis	YES
6335230	30649637	YT	2	contributed to the design and manuscript preparation|performed the clinical studies|performed the clinical follow up	contributed to the design and manuscript preparation	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
6335230	30649637	YT	2	contributed to the design and manuscript preparation|performed the clinical studies|performed the clinical follow up	performed the clinical studies	Performed the experiments	Investigation	YES
6335230	30649637	YT	2	contributed to the design and manuscript preparation|performed the clinical studies|performed the clinical follow up	performed the clinical follow up	Performed the experiments	Investigation	YES
4414573	25923658	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414573	25923658	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414573	25923658	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414573	25923658	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414573	25923658	KP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414573	25923658	KP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414573	25923658	KP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414573	25923658	KP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414573	25923658	MH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414573	25923658	MH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414573	25923658	MH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414573	25923658	MT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414573	25923658	MT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414573	25923658	MT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414573	25923658	MT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414573	25923658	OA	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414573	25923658	OA	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414573	25923658	OA	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414573	25923658	PJ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414573	25923658	PJ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414573	25923658	PJ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414573	25923658	PM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414573	25923658	PM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414573	25923658	PM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414573	25923658	PM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414573	25923658	PS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414573	25923658	PS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414573	25923658	PS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414573	25923658	RV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414573	25923658	RV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414573	25923658	RV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414573	25923658	RV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5637072	29020945	GBD	1	Acquisition of data	Acquisition of data	Performed the experiments	Investigation	YES
5637072	29020945	HL	1	Experimental concept and design|Manuscript revision|Given final approval of the version	Experimental concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5637072	29020945	HL	1	Experimental concept and design|Manuscript revision|Given final approval of the version	Manuscript revision	Wrote the paper	Writing - Review & Editing	YES
5637072	29020945	HL	1	Experimental concept and design|Manuscript revision|Given final approval of the version	Given final approval of the version	-	-	NO
5637072	29020945	HLZ	1	Analysis and interpretation	Analysis and interpretation	Analyzed the data	Formal analysis	YES
5637072	29020945	JJL	1	Experimental concept and design|Acquisition of data|Analysis and interpretation|Manuscript writing|Manuscript revision	Experimental concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5637072	29020945	JJL	1	Experimental concept and design|Acquisition of data|Analysis and interpretation|Manuscript writing|Manuscript revision	Acquisition of data	Performed the experiments	Investigation	YES
5637072	29020945	JJL	1	Experimental concept and design|Acquisition of data|Analysis and interpretation|Manuscript writing|Manuscript revision	Analysis and interpretation	Analyzed the data	Formal analysis	YES
5637072	29020945	JJL	1	Experimental concept and design|Acquisition of data|Analysis and interpretation|Manuscript writing|Manuscript revision	Manuscript writing	Wrote the paper	Writing - Original Draft	YES
5637072	29020945	JJL	1	Experimental concept and design|Acquisition of data|Analysis and interpretation|Manuscript writing|Manuscript revision	Manuscript revision	Wrote the paper	Writing - Review & Editing	YES
5637072	29020945	KJY	1	Acquisition of data	Acquisition of data	Performed the experiments	Investigation	YES
5637072	29020945	MQY	1	Experimental concept and design	Experimental concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5637072	29020945	QL	1	Analysis and interpretation	Analysis and interpretation	Analyzed the data	Formal analysis	YES
5637072	29020945	XC	1	Acquisition of data|Analysis and interpretation|Manuscript writing|Manuscript revision	Acquisition of data	Performed the experiments	Investigation	YES
5637072	29020945	XC	1	Acquisition of data|Analysis and interpretation|Manuscript writing|Manuscript revision	Analysis and interpretation	Analyzed the data	Formal analysis	YES
5637072	29020945	XC	1	Acquisition of data|Analysis and interpretation|Manuscript writing|Manuscript revision	Manuscript writing	Wrote the paper	Writing - Original Draft	YES
5637072	29020945	XC	1	Acquisition of data|Analysis and interpretation|Manuscript writing|Manuscript revision	Manuscript revision	Wrote the paper	Writing - Review & Editing	YES
5637072	29020945	ZFP	1	Analysis and interpretation	Analysis and interpretation	Analyzed the data	Formal analysis	YES
1913553	17622346	GG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1913553	17622346	GG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1913553	17622346	GG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1913553	17622346	KO	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1913553	17622346	KO	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1913553	17622346	RB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1913553	17622346	RB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1913553	17622346	RB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1913553	17622346	TC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5735074	29312388	AR-B	PLoS52	conceived and designed the project|contributed with reagents, materials, and analysis tools|wrote the paper	conceived and designed the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5735074	29312388	AR-B	PLoS52	conceived and designed the project|contributed with reagents, materials, and analysis tools|wrote the paper	contributed with reagents, materials, and analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5735074	29312388	AR-B	PLoS52	conceived and designed the project|contributed with reagents, materials, and analysis tools|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5735074	29312388	CA	PLoS52	conceived and designed the project|analyzed the data|contributed with reagents, materials, and analysis tools|wrote the paper	conceived and designed the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5735074	29312388	CA	PLoS52	conceived and designed the project|analyzed the data|contributed with reagents, materials, and analysis tools|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5735074	29312388	CA	PLoS52	conceived and designed the project|analyzed the data|contributed with reagents, materials, and analysis tools|wrote the paper	contributed with reagents, materials, and analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5735074	29312388	CA	PLoS52	conceived and designed the project|analyzed the data|contributed with reagents, materials, and analysis tools|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5735074	29312388	IM	PLoS52	collected the samples|wrote the paper	collected the samples	Performed the experiments	Investigation	YES
5735074	29312388	IM	PLoS52	collected the samples|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5735074	29312388	JD	PLoS52	were responsible for all plant metabolomics workflows|analyzed the data|wrote the paper	were responsible for all plant metabolomics workflows	Performed the experiments	Investigation|Methodology	YES
5735074	29312388	JD	PLoS52	were responsible for all plant metabolomics workflows|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5735074	29312388	JD	PLoS52	were responsible for all plant metabolomics workflows|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5735074	29312388	NR	PLoS52	conceived and designed the project	conceived and designed the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5735074	29312388	TJ	PLoS52	were responsible for all plant metabolomics workflows|analyzed the data|wrote the paper	were responsible for all plant metabolomics workflows	Performed the experiments	Investigation|Methodology	YES
5735074	29312388	TJ	PLoS52	were responsible for all plant metabolomics workflows|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5735074	29312388	TJ	PLoS52	were responsible for all plant metabolomics workflows|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3844243	24319359	Benjamin Henninger	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
3844243	24319359	Miriam Reichert	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
5059226	27730571	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5059226	27730571	DDH	PLoS52	conceived the idea and designed the experiments|analyzed the data	conceived the idea and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5059226	27730571	DDH	PLoS52	conceived the idea and designed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5059226	27730571	HN	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5059226	27730571	MW	PLoS52	conceived the idea and designed the experiments|analyzed the data|wrote the manuscript	conceived the idea and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5059226	27730571	MW	PLoS52	conceived the idea and designed the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5059226	27730571	MW	PLoS52	conceived the idea and designed the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5059226	27730571	RN	PLoS52	conceived the idea and designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	conceived the idea and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5059226	27730571	RN	PLoS52	conceived the idea and designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5059226	27730571	RN	PLoS52	conceived the idea and designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5059226	27730571	RN	PLoS52	conceived the idea and designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5059226	27730571	The authors	PLoS52	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
6340911	30666513	AH	2	oversaw the experimental procedures and the writing of the manuscript	oversaw the experimental procedures and the writing of the manuscript	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Original Draft	YES
6340911	30666513	HBS	2	performed pbmc isolation from healthy donor blood	performed pbmc isolation from healthy donor blood	Performed the experiments	Investigation	YES
6340911	30666513	MB	2	performed biodistribution studies	performed biodistribution studies	Performed the experiments	Investigation	YES
6340911	30666513	MS	2	oversaw the experimental procedures and the writing of the manuscript	oversaw the experimental procedures and the writing of the manuscript	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Original Draft	YES
6340911	30666513	NLA	2	performed pbmc isolation from healthy donor blood	performed pbmc isolation from healthy donor blood	Performed the experiments	Investigation	YES
6340911	30666513	SGN	2	performed image analysis	performed image analysis	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
6340911	30666513	SM	2	established the immunofluorescence staining methods required to characterize mr expression in the atherosclerotic lesions and interpreted the images	established the immunofluorescence staining methods required to characterize mr expression in the atherosclerotic lesions and interpreted the images	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
6340911	30666513	WW	2	oversaw the experimental procedures and the writing of the manuscript	oversaw the experimental procedures and the writing of the manuscript	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Original Draft	YES
6340911	30666513	YL	2	established the immunofluorescence staining methods required to characterize mr expression in the atherosclerotic lesions and interpreted the images	established the immunofluorescence staining methods required to characterize mr expression in the atherosclerotic lesions and interpreted the images	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
6340911	30666513	ZV	2	designed the experiments and wrote the manuscript	designed the experiments and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4414574	25923654	BR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414574	25923654	BR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414574	25923654	BR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414574	25923654	BR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414574	25923654	BR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414574	25923654	MA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414574	25923654	MA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414574	25923654	MA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414574	25923654	MA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414574	25923654	MA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5637074	29020923	All authors	2	discussed and interpreted the results of the analyses	discussed and interpreted the results of the analyses	Analyzed the data	Formal analysis	YES
5637074	29020923	GY	2	designed and performed the analyses	designed and performed the analyses	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5637074	29020923	MDP	2	conceived and supervised the study	conceived and supervised the study	Conceived and designed the experiments	Conceptualization|Supervision	YES
5637074	29020923	XB	2	conceived and supervised the study	conceived and supervised the study	Conceived and designed the experiments	Conceptualization|Supervision	YES
4332738	25694052	KLH	2	conducted the statistical analysis	conducted the statistical analysis	Analyzed the data	Formal analysis	YES
1913554	17622357	AL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1913554	17622357	AL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1913554	17622357	AL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1913554	17622357	AL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1913554	17622357	HB	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1913554	17622357	NK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1913554	17622357	NK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1913554	17622357	NK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1913554	17622357	NK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1913554	17622357	NK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1913554	17622357	SK	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1913554	17622357	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1913554	17622357	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1913554	17622357	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1913554	17622357	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1913554	17622357	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5735103	29312397	AM	2	had the original idea for the article and carried out the conceptualization of the article	had the original idea for the article and carried out the conceptualization of the article	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5735103	29312397	TC	2	did the initial data collection	did the initial data collection	Performed the experiments	Investigation	YES
5735103	29312397	TM	2	had the original idea for the article and carried out the conceptualization of the article|then led the write-up of the manuscript and all co-authors read and revised the manuscript	had the original idea for the article and carried out the conceptualization of the article	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5735103	29312397	TM	2	had the original idea for the article and carried out the conceptualization of the article|then led the write-up of the manuscript and all co-authors read and revised the manuscript	then led the write-up of the manuscript and all co-authors read and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5735103	29312397	VC	2	then led the write-up of the manuscript and all co-authors read and revised the manuscript	then led the write-up of the manuscript and all co-authors read and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5059232	27730572	All	2	authors read and approved the final manuscript	authors read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5059232	27730572	DHEC	2	conceived experiments	conceived experiments	Conceived and designed the experiments	Conceptualization	YES
5059232	27730572	KS	2	conceived experiments	conceived experiments	Conceived and designed the experiments	Conceptualization	YES
5059232	27730572	PSM	2	conceived experiments|wrote the manuscript|carried out the experiments	conceived experiments	Conceived and designed the experiments	Conceptualization	YES
5059232	27730572	PSM	2	conceived experiments|wrote the manuscript|carried out the experiments	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5059232	27730572	PSM	2	conceived experiments|wrote the manuscript|carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5059232	27730572	QCM	2	authors read and approved the final manuscript	authors read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5059232	27730572	SPO	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
6346696	30680469	AK	PLoS52	commented on the manuscript, and all authors approved the final version of the manuscript	commented on the manuscript, and all authors approved the final version of the manuscript	-	-	NO
6346696	30680469	All authors	PLoS52	participated in the data acquisition	participated in the data acquisition	Performed the experiments	Investigation	YES
6346696	30680469	IJ	PLoS52	analyzed the data|commented on the manuscript, and all authors approved the final version of the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
6346696	30680469	IJ	PLoS52	analyzed the data|commented on the manuscript, and all authors approved the final version of the manuscript	commented on the manuscript, and all authors approved the final version of the manuscript	-	-	NO
6346696	30680469	JK	PLoS52	commented on the manuscript, and all authors approved the final version of the manuscript	commented on the manuscript, and all authors approved the final version of the manuscript	-	-	NO
6346696	30680469	MS	PLoS52	commented on the manuscript, and all authors approved the final version of the manuscript	commented on the manuscript, and all authors approved the final version of the manuscript	-	-	NO
6346696	30680469	SA	PLoS52	designed the study|analyzed the data|drafted the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
6346696	30680469	SA	PLoS52	designed the study|analyzed the data|drafted the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
6346696	30680469	SA	PLoS52	designed the study|analyzed the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
6346696	30680469	SK	PLoS52	commented on the manuscript, and all authors approved the final version of the manuscript	commented on the manuscript, and all authors approved the final version of the manuscript	-	-	NO
6346696	30680469	TN	PLoS52	designed the study|drafted the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
6346696	30680469	TN	PLoS52	designed the study|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5637078	29020924	FL	PLoS52	performed the experiments|analyzed the data|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5637078	29020924	FL	PLoS52	performed the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5637078	29020924	FL	PLoS52	performed the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5637078	29020924	LPX	PLoS52	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5637078	29020924	LW	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5637078	29020924	SWG	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5637078	29020924	TTS	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5637078	29020924	WHS	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5637078	29020924	YCS	PLoS52	conceived and designed the experiments|analyzed the data|wrote the manuscript|revised the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5637078	29020924	YCS	PLoS52	conceived and designed the experiments|analyzed the data|wrote the manuscript|revised the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5637078	29020924	YCS	PLoS52	conceived and designed the experiments|analyzed the data|wrote the manuscript|revised the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5637078	29020924	YCS	PLoS52	conceived and designed the experiments|analyzed the data|wrote the manuscript|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5637078	29020924	YXQ	PLoS52	conceived and designed the experiments|revised the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5637078	29020924	YXQ	PLoS52	conceived and designed the experiments|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5735124	29312382	The author	2	confirms being the sole contributor of this work and approved it for publication	confirms being the sole contributor of this work and approved it for publication	-	-	NO
1913555	17622343	AH	PLoS5	Performed the experiments|Critical review of the article	Performed the experiments	Performed the experiments	Investigation	YES
1913555	17622343	AH	PLoS5	Performed the experiments|Critical review of the article	Critical review of the article	Wrote the paper	Writing - Review & Editing	YES
1913555	17622343	AV	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Data collection and data interpretation	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1913555	17622343	AV	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Data collection and data interpretation	Analyzed the data	Analyzed the data	Formal analysis	YES
1913555	17622343	AV	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Data collection and data interpretation	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1913555	17622343	AV	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Data collection and data interpretation	Data collection and data interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
1913555	17622343	BB	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Critical review of the article	Performed the experiments	Performed the experiments	Investigation	YES
1913555	17622343	BB	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Critical review of the article	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1913555	17622343	BB	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Critical review of the article	Critical review of the article	Wrote the paper	Writing - Review & Editing	YES
1913555	17622343	CH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Interpretation of data and final responsibility for the decision to submit to publication	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1913555	17622343	CH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Interpretation of data and final responsibility for the decision to submit to publication	Analyzed the data	Analyzed the data	Formal analysis	YES
1913555	17622343	CH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Interpretation of data and final responsibility for the decision to submit to publication	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1913555	17622343	CH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Interpretation of data and final responsibility for the decision to submit to publication	Interpretation of data and final responsibility for the decision to submit to publication	Analyzed the data	Formal analysis	YES
1913555	17622343	EO	PLoS5	Data collection and critical review of the article	Data collection and critical review of the article	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
1913555	17622343	GH	PLoS5	Performed the experiments|Wrote the paper|Data collection and data interpretation|Data collection	Performed the experiments	Performed the experiments	Investigation	YES
1913555	17622343	GH	PLoS5	Performed the experiments|Wrote the paper|Data collection and data interpretation|Data collection	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1913555	17622343	GH	PLoS5	Performed the experiments|Wrote the paper|Data collection and data interpretation|Data collection	Data collection and data interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
1913555	17622343	GH	PLoS5	Performed the experiments|Wrote the paper|Data collection and data interpretation|Data collection	Data collection	Performed the experiments	Investigation	YES
1913555	17622343	GL	PLoS5	Conceived and designed the experiments|Wrote the paper|Data collection	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1913555	17622343	GL	PLoS5	Conceived and designed the experiments|Wrote the paper|Data collection	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1913555	17622343	GL	PLoS5	Conceived and designed the experiments|Wrote the paper|Data collection	Data collection	Performed the experiments	Investigation	YES
1913555	17622343	JA	PLoS5	Conceived and designed the experiments|Interpretation of data and critical review of the article	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1913555	17622343	JA	PLoS5	Conceived and designed the experiments|Interpretation of data and critical review of the article	Interpretation of data and critical review of the article	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
1913555	17622343	JG	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Critical review of the article	Performed the experiments	Performed the experiments	Investigation	YES
1913555	17622343	JG	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Critical review of the article	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1913555	17622343	JG	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Critical review of the article	Critical review of the article	Wrote the paper	Writing - Review & Editing	YES
4609807	26509167	Feng He	2	contributed equally to this work	contributed equally to this work	-	-	NO
4609807	26509167	Limin Wang	2	contributed equally to this work	contributed equally to this work	-	-	NO
4414575	25923783	AMM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414575	25923783	AMM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414575	25923783	AMM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414575	25923783	AMM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414575	25923783	CP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414575	25923783	CP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414575	25923783	CP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414575	25923783	CP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414575	25923783	DP	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414575	25923783	JI	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4414575	25923783	MC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4414575	25923783	MPK	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414575	25923783	MPK	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414575	25923783	RM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4414575	25923783	RT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414575	25923783	RT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414575	25923783	RT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414575	25923783	RT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414575	25923783	WZ	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414575	25923783	WZ	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6353974	30701347	All authors	2	provided substantial contributions to the conception or design of the work	provided substantial contributions to the conception or design of the work	Conceived and designed the experiments	Conceptualization	YES
6353974	30701347	DS	2	helped in drafting the work or revising it critically for important intellectual content|helped in drafting the work or revising it critically for important intellectual content	helped in drafting the work or revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6353974	30701347	DS	2	helped in drafting the work or revising it critically for important intellectual content|helped in drafting the work or revising it critically for important intellectual content	helped in drafting the work or revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6353974	30701347	KN	2	contributed to the acquisition, analysis, or interpretation of data for the work|helped in drafting the work or revising it critically for important intellectual content|helped in drafting the work or revising it critically for important intellectual content	contributed to the acquisition, analysis, or interpretation of data for the work	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
6353974	30701347	KN	2	contributed to the acquisition, analysis, or interpretation of data for the work|helped in drafting the work or revising it critically for important intellectual content|helped in drafting the work or revising it critically for important intellectual content	helped in drafting the work or revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6353974	30701347	KN	2	contributed to the acquisition, analysis, or interpretation of data for the work|helped in drafting the work or revising it critically for important intellectual content|helped in drafting the work or revising it critically for important intellectual content	helped in drafting the work or revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6353974	30701347	KT	2	contributed to the acquisition, analysis, or interpretation of data for the work|helped in drafting the work or revising it critically for important intellectual content	contributed to the acquisition, analysis, or interpretation of data for the work	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
6353974	30701347	KT	2	contributed to the acquisition, analysis, or interpretation of data for the work|helped in drafting the work or revising it critically for important intellectual content	helped in drafting the work or revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6353974	30701347	KY	2	contributed to the acquisition, analysis, or interpretation of data for the work|helped in drafting the work or revising it critically for important intellectual content	contributed to the acquisition, analysis, or interpretation of data for the work	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
6353974	30701347	KY	2	contributed to the acquisition, analysis, or interpretation of data for the work|helped in drafting the work or revising it critically for important intellectual content	helped in drafting the work or revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6353974	30701347	MH	2	contributed to the acquisition, analysis, or interpretation of data for the work	contributed to the acquisition, analysis, or interpretation of data for the work	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
6353974	30701347	RM	2	contributed to the acquisition, analysis, or interpretation of data for the work|helped in drafting the work or revising it critically for important intellectual content	contributed to the acquisition, analysis, or interpretation of data for the work	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
6353974	30701347	RM	2	contributed to the acquisition, analysis, or interpretation of data for the work|helped in drafting the work or revising it critically for important intellectual content	helped in drafting the work or revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5059233	27730570	All authors	2	prepared and proofread the final draft|read and approved the final manuscript	prepared and proofread the final draft	Wrote the paper	Writing - Original Draft	YES
5059233	27730570	All authors	2	prepared and proofread the final draft|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5059233	27730570	CG	2	performed the phenotypic microarray and complete sequencing experiments	performed the phenotypic microarray and complete sequencing experiments	Performed the experiments	Investigation	YES
5059233	27730570	DF	2	conceived the idea and obtained funding for the project	conceived the idea and obtained funding for the project	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
5059233	27730570	JC	2	performed the phenotypic microarray and complete sequencing experiments	performed the phenotypic microarray and complete sequencing experiments	Performed the experiments	Investigation	YES
5059233	27730570	KC	2	conceived the idea and obtained funding for the project	conceived the idea and obtained funding for the project	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
5059233	27730570	TMC	2	performed the phenotypic microarray and complete sequencing experiments	performed the phenotypic microarray and complete sequencing experiments	Performed the experiments	Investigation	YES
5059233	27730570	The French Embassy	2	in malaysia for the awarded fellowships and continuous support	in malaysia for the awarded fellowships and continuous support	-	-	NO
5059233	27730570	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5059233	27730570	WY	2	performed the phenotypic microarray and complete sequencing experiments	performed the phenotypic microarray and complete sequencing experiments	Performed the experiments	Investigation	YES
5059233	27730570	YD	2	conceived the idea and obtained funding for the project	conceived the idea and obtained funding for the project	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
1914062	17637827	JK	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1914062	17637827	JK	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1914062	17637827	MM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1914062	17637827	MM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1914062	17637827	MM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1914062	17637827	MP	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1914062	17637827	MP	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1914062	17637827	MP	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1914062	17637827	NK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1914062	17637827	NK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1914062	17637827	NK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5997602	29574676	all authors	1	Concept and design	Concept and design	Conceived and designed the experiments	Conceptualization	YES
6355889	30706258	CS	2	contributed to the biostatistical analysis	contributed to the biostatistical analysis	Analyzed the data	Formal analysis	YES
6355889	30706258	JPB	2	contributed to the conception, design, drafting, and final approval of manuscript	contributed to the conception, design, drafting, and final approval of manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
6355889	30706258	MRP	2	contributed to the conception, design, and final approval	contributed to the conception, design, and final approval	Conceived and designed the experiments	Conceptualization	YES
6355889	30706258	PC	2	contributed to the conception, design, and final approval	contributed to the conception, design, and final approval	Conceived and designed the experiments	Conceptualization	YES
6355889	30706258	RG	2	contributed to the conception, design, and final approval	contributed to the conception, design, and final approval	Conceived and designed the experiments	Conceptualization	YES
4414576	25923738	CJB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Developed the original concept	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414576	25923738	CJB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Developed the original concept	Analyzed the data	Analyzed the data	Formal analysis	YES
4414576	25923738	CJB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Developed the original concept	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414576	25923738	CJB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Developed the original concept	Developed the original concept	Conceived and designed the experiments	Conceptualization	YES
4414576	25923738	RDK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Developed the original concept	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414576	25923738	RDK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Developed the original concept	Performed the experiments	Performed the experiments	Investigation	YES
4414576	25923738	RDK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Developed the original concept	Analyzed the data	Analyzed the data	Formal analysis	YES
4414576	25923738	RDK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Developed the original concept	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414576	25923738	RDK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Developed the original concept	Developed the original concept	Conceived and designed the experiments	Conceptualization	YES
4414576	25923738	RLHD	PLoS5	Wrote the paper|Developed the original concept	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414576	25923738	RLHD	PLoS5	Wrote the paper|Developed the original concept	Developed the original concept	Conceived and designed the experiments	Conceptualization	YES
4414576	25923738	RSH	PLoS5	Conceived and designed the experiments|Wrote the paper|Developed the original concept	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414576	25923738	RSH	PLoS5	Conceived and designed the experiments|Wrote the paper|Developed the original concept	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414576	25923738	RSH	PLoS5	Conceived and designed the experiments|Wrote the paper|Developed the original concept	Developed the original concept	Conceived and designed the experiments	Conceptualization	YES
4414576	25923738	TGS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Developed the original concept	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414576	25923738	TGS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Developed the original concept	Analyzed the data	Analyzed the data	Formal analysis	YES
4414576	25923738	TGS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Developed the original concept	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414576	25923738	TGS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Developed the original concept	Developed the original concept	Conceived and designed the experiments	Conceptualization	YES
5735125	29312389	All authors	2	listed have made a substantial, direct and intellectual contribution to the work, and approved it for publication	listed have made a substantial, direct and intellectual contribution to the work, and approved it for publication	-	-	NO
3139143	21785703	All authors	2	contributed to the design of the study|contributed to the analysis and interpretation of data	contributed to the design of the study	Conceived and designed the experiments	Methodology	YES
3139143	21785703	All authors	2	contributed to the design of the study|contributed to the analysis and interpretation of data	contributed to the analysis and interpretation of data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
3139143	21785703	C. A. Defanti	2	identified the participants	identified the participants	Performed the experiments	Investigation	YES
3139143	21785703	C. Defanti	2	administered the neuropsychological and neurobehavioural scales	administered the neuropsychological and neurobehavioural scales	-	-	NO
3139143	21785703	E. Chito	2	did the individual interviews	did the individual interviews	Performed the experiments	Investigation	YES
3139143	21785703	L. Sacco	2	identified the participants|administered the neuropsychological and neurobehavioural scales	identified the participants	Performed the experiments	Investigation	YES
3139143	21785703	L. Sacco	2	identified the participants|administered the neuropsychological and neurobehavioural scales	administered the neuropsychological and neurobehavioural scales	-	-	NO
3139143	21785703	M. Sala	2	did the individual interviews	did the individual interviews	Performed the experiments	Investigation	YES
3139143	21785703	P. Tiraboschi	2	drafted the article, and all authors revised it critically for important intellectual content|is the guarantor	drafted the article, and all authors revised it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3139143	21785703	P. Tiraboschi	2	drafted the article, and all authors revised it critically for important intellectual content|is the guarantor	is the guarantor	-	-	NO
3139143	21785703	S. Stefanini	2	administered the neuropsychological and neurobehavioural scales	administered the neuropsychological and neurobehavioural scales	-	-	NO
5061668	27734418	BHZ	1	Contributed materials	Contributed materials	Contributed reagents/materials/analysis tools	Resources	YES
5061668	27734418	JC	1	Contributed materials	Contributed materials	Contributed reagents/materials/analysis tools	Resources	YES
5061668	27734418	MSJ	1	Contributed materials	Contributed materials	Contributed reagents/materials/analysis tools	Resources	YES
5061668	27734418	PC	1	Contributed materials	Contributed materials	Contributed reagents/materials/analysis tools	Resources	YES
5061668	27734418	SS	1	Contributed materials	Contributed materials	Contributed reagents/materials/analysis tools	Resources	YES
5061668	27734418	WHZ	1	Contributed materials	Contributed materials	Contributed reagents/materials/analysis tools	Resources	YES
5061668	27734418	WZ	1	Contributed materials	Contributed materials	Contributed reagents/materials/analysis tools	Resources	YES
5061668	27734418	XDG	1	Contributed materials	Contributed materials	Contributed reagents/materials/analysis tools	Resources	YES
5061668	27734418	YG	1	Contributed materials	Contributed materials	Contributed reagents/materials/analysis tools	Resources	YES
5637092	29020917	BA	1	Conceived the project|Analysed the results|Revised and edited the manuscript	Conceived the project	Conceived and designed the experiments	Conceptualization	YES
5637092	29020917	BA	1	Conceived the project|Analysed the results|Revised and edited the manuscript	Analysed the results	Analyzed the data	Formal analysis	YES
5637092	29020917	BA	1	Conceived the project|Analysed the results|Revised and edited the manuscript	Revised and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5637092	29020917	CF	1	Conducted the experiments	Conducted the experiments	Performed the experiments	Investigation	YES
5637092	29020917	FL	1	Conceived the project|Conducted the experiments|Analysed the results|Wrote the first draft of the manuscript and figures|Revised and edited the manuscript	Conceived the project	Conceived and designed the experiments	Conceptualization	YES
5637092	29020917	FL	1	Conceived the project|Conducted the experiments|Analysed the results|Wrote the first draft of the manuscript and figures|Revised and edited the manuscript	Conducted the experiments	Performed the experiments	Investigation	YES
5637092	29020917	FL	1	Conceived the project|Conducted the experiments|Analysed the results|Wrote the first draft of the manuscript and figures|Revised and edited the manuscript	Analysed the results	Analyzed the data	Formal analysis	YES
5637092	29020917	FL	1	Conceived the project|Conducted the experiments|Analysed the results|Wrote the first draft of the manuscript and figures|Revised and edited the manuscript	Wrote the first draft of the manuscript and figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5637092	29020917	FL	1	Conceived the project|Conducted the experiments|Analysed the results|Wrote the first draft of the manuscript and figures|Revised and edited the manuscript	Revised and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5637092	29020917	JMR	1	Analysed the results|Performed bioinformatics analyses|Revised and edited the manuscript	Analysed the results	Analyzed the data	Formal analysis	YES
5637092	29020917	JMR	1	Analysed the results|Performed bioinformatics analyses|Revised and edited the manuscript	Performed bioinformatics analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5637092	29020917	JMR	1	Analysed the results|Performed bioinformatics analyses|Revised and edited the manuscript	Revised and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5637092	29020917	LJZ	1	Revised and edited the manuscript	Revised and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5637092	29020917	MS	1	Analysed the results|Performed bioinformatics analyses|Revised and edited the manuscript	Analysed the results	Analyzed the data	Formal analysis	YES
5637092	29020917	MS	1	Analysed the results|Performed bioinformatics analyses|Revised and edited the manuscript	Performed bioinformatics analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5637092	29020917	MS	1	Analysed the results|Performed bioinformatics analyses|Revised and edited the manuscript	Revised and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5637092	29020917	TN	1	Conducted the experiments|Revised and edited the manuscript	Conducted the experiments	Performed the experiments	Investigation	YES
5637092	29020917	TN	1	Conducted the experiments|Revised and edited the manuscript	Revised and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
1914377	17653262	AK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1914377	17653262	AK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1914377	17653262	AK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1914377	17653262	HH	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1914377	17653262	KS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1914377	17653262	KS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1914377	17653262	KS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1914377	17653262	KS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1914377	17653262	KS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1914377	17653262	SM	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1914377	17653262	SM	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1914377	17653262	YK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1914377	17653262	YK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1914377	17653262	YK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5735977	29312367	JA	2	contributed namely to the section about damage indicators	contributed namely to the section about damage indicators	-	-	NO
5735977	29312367	LB	2	contributed specifically to the stomatal conductance and mesophyll conductance sections|is also the author of all the parts of the text dealing with remote sensing techniques	contributed specifically to the stomatal conductance and mesophyll conductance sections	Performed the experiments	Investigation	YES
5735977	29312367	LB	2	contributed specifically to the stomatal conductance and mesophyll conductance sections|is also the author of all the parts of the text dealing with remote sensing techniques	is also the author of all the parts of the text dealing with remote sensing techniques	-	-	NO
5735977	29312367	LU	2	is the major contributor to all other sections	is the major contributor to all other sections	-	-	NO
6362178	30715647	EFS	2	contributed to acquisition of data and critical reviewing of the manuscript	contributed to acquisition of data and critical reviewing of the manuscript	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Resources|Writing - Review & Editing	YES
6362178	30715647	GMK	2	contributed to data analysis, data interpretation, and critical reviewing of the manuscript	contributed to data analysis, data interpretation, and critical reviewing of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
6362178	30715647	MC	2	contributed to the concept, data analysis, data interpretation, and writing the manuscript	contributed to the concept, data analysis, data interpretation, and writing the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Resources|Writing - Original Draft	YES
6362178	30715647	OSH	2	contributed to the concept, data interpretation, and critical reviewing of the manuscript	contributed to the concept, data interpretation, and critical reviewing of the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Resources|Writing - Review & Editing	YES
6362178	30715647	RB	2	contributed to the concept, data interpretation, and critical reviewing of the manuscript	contributed to the concept, data interpretation, and critical reviewing of the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Resources|Writing - Review & Editing	YES
6362178	30715647	SVSG	2	contributed to data-analysis, data interpretation, and critical reviewing of the manuscript	contributed to data-analysis, data interpretation, and critical reviewing of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
6362178	30715647	VF	2	contributed to acquisition of data and critical reviewing of the manuscript	contributed to acquisition of data and critical reviewing of the manuscript	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Resources|Writing - Review & Editing	YES
4414577	25923543	DN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414577	25923543	DN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414577	25923543	DN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414577	25923543	DN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414577	25923543	DN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414577	25923543	FLL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414577	25923543	FLL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414577	25923543	FLL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414577	25923543	FLL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414577	25923543	JHH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414577	25923543	JHH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414577	25923543	LTLT	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4414577	25923543	LTLT	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414577	25923543	SMS	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414577	25923543	SMS	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4414577	25923543	ZH	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414577	25923543	ZH	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414577	25923543	ZH	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414577	25923543	ZH	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1914378	17653264	BB	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1914378	17653264	FP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Led the work group	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1914378	17653264	FP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Led the work group	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1914378	17653264	FP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Led the work group	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1914378	17653264	FP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Led the work group	Led the work group	-	-	NO
1914378	17653264	KM	PLoS5	Laboratory director|Supervised study	Laboratory director	-	-	NO
1914378	17653264	KM	PLoS5	Laboratory director|Supervised study	Supervised study	-	Supervision	YES
1914378	17653264	SF	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1914378	17653264	SF	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1914378	17653264	SF	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1914378	17653264	YB	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1914378	17653264	YB	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5637254	29020934	All authors	2	have read and approved the final version of this manuscript	have read and approved the final version of this manuscript	-	-	NO
5637254	29020934	HL	2	designed experiments, analyzed data, and wrote the paper	designed experiments, analyzed data, and wrote the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5637254	29020934	JJP	2	performed research, confirmed bioinformatics data, performed plant defense assays, and subsequent data analysis	performed research, confirmed bioinformatics data, performed plant defense assays, and subsequent data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5637254	29020934	SMM	2	designed experiments, analyzed data, and wrote the paper	designed experiments, analyzed data, and wrote the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5637254	29020934	XZ	2	designed experiments, analyzed data, and wrote the paper|performed research, confirmed bioinformatics data, performed plant defense assays, and subsequent data analysis	designed experiments, analyzed data, and wrote the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5637254	29020934	XZ	2	designed experiments, analyzed data, and wrote the paper|performed research, confirmed bioinformatics data, performed plant defense assays, and subsequent data analysis	performed research, confirmed bioinformatics data, performed plant defense assays, and subsequent data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5063827	27739052	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5063827	27739052	GE	2	designed and guided the study and edited the manuscript	designed and guided the study and edited the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Review & Editing	YES
5063827	27739052	GOO	2	carried out the main experiments, interpreted the data and wrote the manuscript	carried out the main experiments, interpreted the data and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5063827	27739052	HS	2	did the electron microscopy and xeds analyses of the interactions	did the electron microscopy and xeds analyses of the interactions	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5736527	29326734	AA	2	performed the athb13-gst protein purification and emsa experiments	performed the athb13-gst protein purification and emsa experiments	Performed the experiments	Investigation	YES
5736527	29326734	BM-R	2	conceived the idea for the study	conceived the idea for the study	Conceived and designed the experiments	Conceptualization	YES
5736527	29326734	E-M	2	performed the athb13-gst protein purification and emsa experiments	performed the athb13-gst protein purification and emsa experiments	Performed the experiments	Investigation	YES
5736527	29326734	PR	2	made the crosses, confirmed their genotypes, and performed drought stress experiments under the	made the crosses, confirmed their genotypes, and performed drought stress experiments under the	Performed the experiments	Investigation	YES
5736527	29326734	RC	2	supervised the and performed drought stress experiments under the	supervised the and performed drought stress experiments under the	Performed the experiments	Investigation|Supervision	YES
5736527	29326734	SB	2	conceived the idea for the study	conceived the idea for the study	Conceived and designed the experiments	Conceptualization	YES
5736527	29326734	SE-M	2	performed the jub1 promoter deletion study and the y1h screen|performed the drought stress experiments	performed the jub1 promoter deletion study and the y1h screen	Performed the experiments	Investigation	YES
5736527	29326734	SE-M	2	performed the jub1 promoter deletion study and the y1h screen|performed the drought stress experiments	performed the drought stress experiments	Performed the experiments	Investigation	YES
5736527	29326734	VT	2	performed the drought stress experiments|performed the athb13-gst protein purification and emsa experiments	performed the drought stress experiments	Performed the experiments	Investigation	YES
5736527	29326734	VT	2	performed the drought stress experiments|performed the athb13-gst protein purification and emsa experiments	performed the athb13-gst protein purification and emsa experiments	Performed the experiments	Investigation	YES
6365580	30725219	CSB	2	validated all the study parameters and reviewed the entire manuscript	validated all the study parameters and reviewed the entire manuscript	Performed the experiments|Wrote the paper	Validation|Writing - Review & Editing	YES
6365580	30725219	MPY	2	collected all the data, analyzed the data with help of bio-statistician, and wrote the manuscript	collected all the data, analyzed the data with help of bio-statistician, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6365580	30725219	SB	2	collected all the data, analyzed the data with help of bio-statistician, and wrote the manuscript	collected all the data, analyzed the data with help of bio-statistician, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4414579	25923774	AT	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414579	25923774	AT	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414579	25923774	CH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414579	25923774	CH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414579	25923774	ES	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414579	25923774	ES	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414579	25923774	ES	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414579	25923774	ES	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414579	25923774	OK	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414579	25923774	OK	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414579	25923774	OK	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414579	25923774	RBE	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414579	25923774	RBE	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414579	25923774	SJ	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414579	25923774	SJ	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414579	25923774	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414579	25923774	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414579	25923774	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414579	25923774	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414579	25923774	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414579	25923774	TN	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414579	25923774	TN	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414579	25923774	TN	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414579	25923774	TvdM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414579	25923774	TvdM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414579	25923774	TvdM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414579	25923774	TvdM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1914379	17653286	JB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1914379	17653286	JB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1914379	17653286	JB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1914379	17653286	JS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1914379	17653286	JS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1914379	17653286	JS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5637328	29020939	AC-S	PLoS52	participated in the obtention of experimental data	participated in the obtention of experimental data	Performed the experiments	Investigation	YES
5637328	29020939	AS	PLoS52	performed most of the experiments|analysed the data	performed most of the experiments	Performed the experiments	Investigation	YES
5637328	29020939	AS	PLoS52	performed most of the experiments|analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
5637328	29020939	FF	PLoS52	participated in the obtention of experimental data|conceived and designed the study	participated in the obtention of experimental data	Performed the experiments	Investigation	YES
5637328	29020939	FF	PLoS52	participated in the obtention of experimental data|conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5637328	29020939	IM	PLoS52	participated in the obtention of experimental data|conceived and designed the study|analysed the data|wrote the paper	participated in the obtention of experimental data	Performed the experiments	Investigation	YES
5637328	29020939	IM	PLoS52	participated in the obtention of experimental data|conceived and designed the study|analysed the data|wrote the paper	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5637328	29020939	IM	PLoS52	participated in the obtention of experimental data|conceived and designed the study|analysed the data|wrote the paper	analysed the data	Analyzed the data	Formal analysis	YES
5637328	29020939	IM	PLoS52	participated in the obtention of experimental data|conceived and designed the study|analysed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5637328	29020939	IV	PLoS52	participated in the obtention of experimental data	participated in the obtention of experimental data	Performed the experiments	Investigation	YES
5637328	29020939	IVB	PLoS52	participated in the obtention of experimental data|conceived and designed the study|analysed the data|wrote the paper	participated in the obtention of experimental data	Performed the experiments	Investigation	YES
5637328	29020939	IVB	PLoS52	participated in the obtention of experimental data|conceived and designed the study|analysed the data|wrote the paper	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5637328	29020939	IVB	PLoS52	participated in the obtention of experimental data|conceived and designed the study|analysed the data|wrote the paper	analysed the data	Analyzed the data	Formal analysis	YES
5637328	29020939	IVB	PLoS52	participated in the obtention of experimental data|conceived and designed the study|analysed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5637328	29020939	JIS-M	PLoS52	performed most of the experiments|analysed the data	performed most of the experiments	Performed the experiments	Investigation	YES
5637328	29020939	JIS-M	PLoS52	performed most of the experiments|analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
5637328	29020939	MPA	PLoS52	participated in the obtention of experimental data	participated in the obtention of experimental data	Performed the experiments	Investigation	YES
5736534	29326738	All authors	2	listed, have made substantial, direct and intellectual contribution to the work, and approved it for publication	listed, have made substantial, direct and intellectual contribution to the work, and approved it for publication	-	-	NO
4414580	25923976	BLF	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414580	25923976	BLF	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414580	25923976	BLF	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414580	25923976	GL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414580	25923976	GL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414580	25923976	GL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414580	25923976	GL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414580	25923976	PS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414580	25923976	PS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414580	25923976	PS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414580	25923976	SS	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6367490	30734113	DVG	2	performed the data analysis and wrote the manuscript	performed the data analysis and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6367490	30734113	EFS	2	contributed to the patient inclusion, data acquisition, and manuscript revision	contributed to the patient inclusion, data acquisition, and manuscript revision	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Resources|Writing - Review & Editing	YES
6367490	30734113	GDK	2	performed the metrics extraction from images, analysed the data, and wrote the manuscript	performed the metrics extraction from images, analysed the data, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Visualization|Writing - Original Draft	YES
6367490	30734113	GMK	2	contributed to the patient inclusion, data acquisition, and manuscript revision	contributed to the patient inclusion, data acquisition, and manuscript revision	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Resources|Writing - Review & Editing	YES
6367490	30734113	OSH	2	contributed to the study design, patient inclusion, data acquisition, and manuscript revision	contributed to the study design, patient inclusion, data acquisition, and manuscript revision	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Methodology|Resources|Writing - Review & Editing	YES
6367490	30734113	RAJOD	2	contributed in the critical review of the manuscript	contributed in the critical review of the manuscript	Wrote the paper	Writing - Review & Editing	YES
6367490	30734113	RB	2	designed and managed the study, developed software for image processing, and wrote the manuscript	designed and managed the study, developed software for image processing, and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Methodology|Project administration|Software|Visualization|Writing - Original Draft	YES
6367490	30734113	VF	2	contributed to the patient inclusion, data acquisition, and manuscript revision	contributed to the patient inclusion, data acquisition, and manuscript revision	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Resources|Writing - Review & Editing	YES
5074941	27770389	All	2	animal experiment procedures were conducted in accordance with the guidelines of the animal welfare act and all procedures and protocols were approved by the institutional animal care and use committee of the sichuan agricultural university	animal experiment procedures were conducted in accordance with the guidelines of the animal welfare act and all procedures and protocols were approved by the institutional animal care and use committee of the sichuan agricultural university	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5074941	27770389	All authors	2	contributed to the design of the experiments|read and approved the final manuscript	contributed to the design of the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5074941	27770389	All authors	2	contributed to the design of the experiments|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5074941	27770389	FZ	2	performed the experiments and drafted the manuscript	performed the experiments and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5074941	27770389	Grassland Science	2	for providing experimental animals	for providing experimental animals	-	-	NO
5074941	27770389	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
1914380	17653282	AB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1914380	17653282	AB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1914380	17653282	AF	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1914380	17653282	AF	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1914380	17653282	AF	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1914380	17653282	AF	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1914380	17653282	AK	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1914380	17653282	AK	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1914380	17653282	AK	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1914380	17653282	BS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1914380	17653282	BS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1914380	17653282	BS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1914380	17653282	BS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1914380	17653282	CL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1914380	17653282	CL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1914380	17653282	CL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1914380	17653282	DF	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1914380	17653282	DF	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1914380	17653282	HJ	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1914380	17653282	HJ	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1914380	17653282	HL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1914380	17653282	HL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1914380	17653282	JN	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1914380	17653282	JN	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1914380	17653282	MB	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1914380	17653282	MB	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1914380	17653282	MF	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1914380	17653282	MF	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1914380	17653282	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1914380	17653282	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1914380	17653282	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1914380	17653282	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1914380	17653282	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1914380	17653282	OL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1914380	17653282	OL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1914380	17653282	OL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1914380	17653282	RS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1914380	17653282	RS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1914380	17653282	RS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1914380	17653282	SB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1914380	17653282	SB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1914380	17653282	SB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1914380	17653282	SB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1914380	17653282	UG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1914380	17653282	UG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1914380	17653282	UG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3140783	21789276	All authors	2	contributed to the design of the study	contributed to the design of the study	Conceived and designed the experiments	Methodology	YES
3140783	21789276	L. J. Irastorza	2	contributed to the analysis and interpretation of data, drafted the article and revised	contributed to the analysis and interpretation of data, drafted the article and revised	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft|Writing - Review & Editing	YES
3140783	21789276	P. Banuelos	2	identified the participants, did the individual interviews and administered the neuropsychological scales	identified the participants, did the individual interviews and administered the neuropsychological scales	Performed the experiments	Investigation	YES
3140783	21789276	P. Corujo	2	identified the participants, did the individual interviews and administered the neuropsychological scales	identified the participants, did the individual interviews and administered the neuropsychological scales	Performed the experiments	Investigation	YES
5637334	29020946	AF	2	conducted the analysis	conducted the analysis	Performed the experiments	Investigation	YES
5637334	29020946	All authors	2	conceived and designed experiments and wrote and edited the manuscript	conceived and designed experiments and wrote and edited the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5637334	29020946	PR	2	conducted the analysis	conducted the analysis	Performed the experiments	Investigation	YES
5736878	29326747	FH	PLoS52	conceived the research and designed the experiments|analyzed data and wrote the manuscript	conceived the research and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5736878	29326747	FH	PLoS52	conceived the research and designed the experiments|analyzed data and wrote the manuscript	analyzed data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5736878	29326747	JX	PLoS52	conceived the research and designed the experiments|performed the experiments|analyzed data and wrote the manuscript	conceived the research and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5736878	29326747	JX	PLoS52	conceived the research and designed the experiments|performed the experiments|analyzed data and wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5736878	29326747	JX	PLoS52	conceived the research and designed the experiments|performed the experiments|analyzed data and wrote the manuscript	analyzed data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5736878	29326747	LZ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5736878	29326747	PL	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
4414581	25923118	CAH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Provided critical revisions to the manuscript and approved the final version prior to submission	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414581	25923118	CAH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Provided critical revisions to the manuscript and approved the final version prior to submission	Analyzed the data	Analyzed the data	Formal analysis	YES
4414581	25923118	CAH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Provided critical revisions to the manuscript and approved the final version prior to submission	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414581	25923118	CAH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Provided critical revisions to the manuscript and approved the final version prior to submission	Provided critical revisions to the manuscript and approved the final version prior to submission	Wrote the paper	Writing - Review & Editing	YES
4414581	25923118	DF	PLoS5	Conceived and designed the experiments|Provided critical revisions to the manuscript and approved the final version prior to submission	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414581	25923118	DF	PLoS5	Conceived and designed the experiments|Provided critical revisions to the manuscript and approved the final version prior to submission	Provided critical revisions to the manuscript and approved the final version prior to submission	Wrote the paper	Writing - Review & Editing	YES
4414581	25923118	JMB	PLoS5	Conceived and designed the experiments|Wrote the paper|Provided critical revisions to the manuscript and approved the final version prior to submission	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414581	25923118	JMB	PLoS5	Conceived and designed the experiments|Wrote the paper|Provided critical revisions to the manuscript and approved the final version prior to submission	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414581	25923118	JMB	PLoS5	Conceived and designed the experiments|Wrote the paper|Provided critical revisions to the manuscript and approved the final version prior to submission	Provided critical revisions to the manuscript and approved the final version prior to submission	Wrote the paper	Writing - Review & Editing	YES
4414581	25923118	LK	PLoS5	Conceived and designed the experiments|Performed the experiments|Provided critical revisions to the manuscript and approved the final version prior to submission	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414581	25923118	LK	PLoS5	Conceived and designed the experiments|Performed the experiments|Provided critical revisions to the manuscript and approved the final version prior to submission	Performed the experiments	Performed the experiments	Investigation	YES
4414581	25923118	LK	PLoS5	Conceived and designed the experiments|Performed the experiments|Provided critical revisions to the manuscript and approved the final version prior to submission	Provided critical revisions to the manuscript and approved the final version prior to submission	Wrote the paper	Writing - Review & Editing	YES
4414581	25923118	PJR	PLoS5	Conceived and designed the experiments|Provided critical revisions to the manuscript and approved the final version prior to submission	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414581	25923118	PJR	PLoS5	Conceived and designed the experiments|Provided critical revisions to the manuscript and approved the final version prior to submission	Provided critical revisions to the manuscript and approved the final version prior to submission	Wrote the paper	Writing - Review & Editing	YES
5075331	27771916	Both authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5075331	27771916	IC	2	performed the research and wrote the paper	performed the research and wrote the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5075331	27771916	SK	2	designed the research and developed the experimental setup	designed the research and developed the experimental setup	Conceived and designed the experiments	Methodology	YES
6368634	30737563	DAP	2	developed the personalised insulin calculator and contributed to the study design, statistical analysis, and writing and revising the manuscript	developed the personalised insulin calculator and contributed to the study design, statistical analysis, and writing and revising the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
6368634	30737563	ELK	2	contributed to the data collection and revising the manuscript	contributed to the data collection and revising the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
6368634	30737563	JC	2	contributed to the statistical analysis and revising the manuscript	contributed to the statistical analysis and revising the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
6368634	30737563	LLM	2	performed the data collection and contributed to the study design, statistical analysis, and writing and revising the manuscript	performed the data collection and contributed to the study design, statistical analysis, and writing and revising the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
6368634	30737563	RJH	2	contributed to the study design and revising manuscript	contributed to the study design and revising manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
6368634	30737563	TA	2	contributed to the study design and revising the manuscript	contributed to the study design and revising the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
1914381	17653283	JC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1914381	17653283	JC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1914381	17653283	JC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1914381	17653283	JC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1914381	17653283	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1914381	17653283	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1914381	17653283	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1914381	17653283	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1914381	17653283	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1914381	17653283	SL	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1914381	17653283	SL	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414582	25923785	HU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414582	25923785	HU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414582	25923785	HU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414582	25923785	HU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414582	25923785	HU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414582	25923785	KY	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414582	25923785	KY	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4414582	25923785	SK	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414582	25923785	SK	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4414582	25923785	YI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414582	25923785	YI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414582	25923785	YI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414582	25923785	YI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414582	25923785	YI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4615854	26523278	Jiaming Liu	2	equally contributed to this work	equally contributed to this work	-	-	NO
4615854	26523278	Jing Sun	2	equally contributed to this work	equally contributed to this work	-	-	NO
5637355	29020922	AP	2	sequenced the genomes	sequenced the genomes	Performed the experiments	Investigation	YES
5637355	29020922	All the authors	2	reviewed critically the manuscript and approved the final version	reviewed critically the manuscript and approved the final version	Wrote the paper	Writing - Review & Editing	YES
5637355	29020922	BC	2	performed the assembly quality control	performed the assembly quality control	Performed the experiments	Investigation|Validation	YES
5637355	29020922	BL	2	processed data for the special set of genes	processed data for the special set of genes	Analyzed the data	Data curation	YES
5637355	29020922	DM	2	processed the samples for the sequencing	processed the samples for the sequencing	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5637355	29020922	DR	2	performed the phylogenetic analysis and the genome assembly, annotation and variant calling|performed the assembly quality control|made the biostatistical analysis|performed the manual annotation of the best candidates obtained|wrote the manuscript	performed the phylogenetic analysis and the genome assembly, annotation and variant calling	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5637355	29020922	DR	2	performed the phylogenetic analysis and the genome assembly, annotation and variant calling|performed the assembly quality control|made the biostatistical analysis|performed the manual annotation of the best candidates obtained|wrote the manuscript	performed the assembly quality control	Performed the experiments	Investigation|Validation	YES
5637355	29020922	DR	2	performed the phylogenetic analysis and the genome assembly, annotation and variant calling|performed the assembly quality control|made the biostatistical analysis|performed the manual annotation of the best candidates obtained|wrote the manuscript	made the biostatistical analysis	Analyzed the data	Formal analysis	YES
5637355	29020922	DR	2	performed the phylogenetic analysis and the genome assembly, annotation and variant calling|performed the assembly quality control|made the biostatistical analysis|performed the manual annotation of the best candidates obtained|wrote the manuscript	performed the manual annotation of the best candidates obtained	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5637355	29020922	DR	2	performed the phylogenetic analysis and the genome assembly, annotation and variant calling|performed the assembly quality control|made the biostatistical analysis|performed the manual annotation of the best candidates obtained|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5637355	29020922	EG	2	processed data for the special set of genes|performed the manual annotation of the best candidates obtained|wrote the manuscript	processed data for the special set of genes	Analyzed the data	Data curation	YES
5637355	29020922	EG	2	processed data for the special set of genes|performed the manual annotation of the best candidates obtained|wrote the manuscript	performed the manual annotation of the best candidates obtained	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5637355	29020922	EG	2	processed data for the special set of genes|performed the manual annotation of the best candidates obtained|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5637355	29020922	ER	2	processed data for the special set of genes	processed data for the special set of genes	Analyzed the data	Data curation	YES
5637355	29020922	LG	2	performed the assembly quality control	performed the assembly quality control	Performed the experiments	Investigation|Validation	YES
5637355	29020922	MZ	2	conceived the project|processed data for the special set of genes|made the biostatistical analysis|wrote the manuscript	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5637355	29020922	MZ	2	conceived the project|processed data for the special set of genes|made the biostatistical analysis|wrote the manuscript	processed data for the special set of genes	Analyzed the data	Data curation	YES
5637355	29020922	MZ	2	conceived the project|processed data for the special set of genes|made the biostatistical analysis|wrote the manuscript	made the biostatistical analysis	Analyzed the data	Formal analysis	YES
5637355	29020922	MZ	2	conceived the project|processed data for the special set of genes|made the biostatistical analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5637355	29020922	PL	2	processed data for the special set of genes	processed data for the special set of genes	Analyzed the data	Data curation	YES
5637355	29020922	PS	2	conceived the project|processed the samples for the sequencing|processed data for the special set of genes|wrote the manuscript	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5637355	29020922	PS	2	conceived the project|processed the samples for the sequencing|processed data for the special set of genes|wrote the manuscript	processed the samples for the sequencing	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5637355	29020922	PS	2	conceived the project|processed the samples for the sequencing|processed data for the special set of genes|wrote the manuscript	processed data for the special set of genes	Analyzed the data	Data curation	YES
5637355	29020922	PS	2	conceived the project|processed the samples for the sequencing|processed data for the special set of genes|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5637355	29020922	RA	2	processed data for the special set of genes|wrote the manuscript	processed data for the special set of genes	Analyzed the data	Data curation	YES
5637355	29020922	RA	2	processed data for the special set of genes|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5637355	29020922	RH	2	conceived the project	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5637355	29020922	RM	2	sequenced the genomes	sequenced the genomes	Performed the experiments	Investigation	YES
5637355	29020922	TC	2	sequenced the genomes	sequenced the genomes	Performed the experiments	Investigation	YES
5737090	29326743	KC	2	wrote the manuscript|critically evaluated the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5737090	29326743	KC	2	wrote the manuscript|critically evaluated the manuscript	critically evaluated the manuscript	-	-	NO
5737090	29326743	KW	2	conceived the idea|revised the manuscript|critically evaluated the manuscript	conceived the idea	Conceived and designed the experiments	Conceptualization	YES
5737090	29326743	KW	2	conceived the idea|revised the manuscript|critically evaluated the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5737090	29326743	KW	2	conceived the idea|revised the manuscript|critically evaluated the manuscript	critically evaluated the manuscript	-	-	NO
5737090	29326743	ML	2	conceived the idea|wrote the manuscript|critically evaluated the manuscript	conceived the idea	Conceived and designed the experiments	Conceptualization	YES
5737090	29326743	ML	2	conceived the idea|wrote the manuscript|critically evaluated the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5737090	29326743	ML	2	conceived the idea|wrote the manuscript|critically evaluated the manuscript	critically evaluated the manuscript	-	-	NO
5737090	29326743	SY	2	critically evaluated the manuscript	critically evaluated the manuscript	-	-	NO
5737090	29326743	YX	2	critically evaluated the manuscript	critically evaluated the manuscript	-	-	NO
4414583	25923697	KI	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4414583	25923697	KI	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4414583	25923697	KY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414583	25923697	KY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414583	25923697	KY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414583	25923697	KY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414583	25923697	MA	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4414583	25923697	MA	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4414583	25923697	MA	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414583	25923697	MM	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4414583	25923697	MM	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4414583	25923697	NA	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4414583	25923697	NY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414583	25923697	NY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414583	25923697	NY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414583	25923697	NY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414583	25923697	SC	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4414583	25923697	SC	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4414583	25923697	TS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414583	25923697	TS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414583	25923697	TS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414583	25923697	TS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414583	25923697	YK	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4414583	25923697	YM	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
6377687	30771115	HO	2	created the design of the study and supervised the project	created the design of the study and supervised the project	Conceived and designed the experiments	Methodology|Supervision	YES
6377687	30771115	NH	2	conducted patient recruit and follow-up	conducted patient recruit and follow-up	Performed the experiments	Investigation	YES
6377687	30771115	PZF	2	contributed to the manuscript revision and editing	contributed to the manuscript revision and editing	Wrote the paper	Writing - Review & Editing	YES
6377687	30771115	TY	2	created the design of the study and supervised the project|conducted patient recruit and follow-up	created the design of the study and supervised the project	Conceived and designed the experiments	Methodology|Supervision	YES
6377687	30771115	TY	2	created the design of the study and supervised the project|conducted patient recruit and follow-up	conducted patient recruit and follow-up	Performed the experiments	Investigation	YES
6377687	30771115	TeT	2	collected and analyzed the data and contributed to the manuscript preparation	collected and analyzed the data and contributed to the manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6377687	30771115	ToT	2	conducted patient recruit and follow-up	conducted patient recruit and follow-up	Performed the experiments	Investigation	YES
5081312	27785778	CLS	1	Planning and designing of study	Planning and designing of study	Conceived and designed the experiments	Methodology	YES
5081312	27785778	CYW	1	Planning and designing of study	Planning and designing of study	Conceived and designed the experiments	Methodology	YES
5081312	27785778	PYQ	1	Planning and designing of study	Planning and designing of study	Conceived and designed the experiments	Methodology	YES
1916400	17653270	CC	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1916400	17653270	CC	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1916400	17653270	CD	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1916400	17653270	CD	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1916400	17653270	CD	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1916400	17653270	CM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1916400	17653270	JC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1916400	17653270	JC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1916400	17653270	JC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1916400	17653270	JC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1916400	17653270	JC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1916400	17653270	JL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1916400	17653270	TH	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1916400	17653270	TH	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1916400	17653270	TH	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5639739	29025408	HC	2	collected the data, carried out the analysis and wrote the manuscript	collected the data, carried out the analysis and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5639739	29025408	JG	2	participated in data collection and the candidate genes analysis	participated in data collection and the candidate genes analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5639739	29025408	JX	2	participated in data collection and the candidate genes analysis	participated in data collection and the candidate genes analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5639739	29025408	LG	2	participated in data collection and the candidate genes analysis	participated in data collection and the candidate genes analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5639739	29025408	LZ	2	designed, led and coordinated the overall study	designed, led and coordinated the overall study	Conceived and designed the experiments	Methodology|Project administration	YES
5639739	29025408	ML	2	designed, led and coordinated the overall study	designed, led and coordinated the overall study	Conceived and designed the experiments	Methodology|Project administration	YES
5639739	29025408	MY	2	designed, led and coordinated the overall study	designed, led and coordinated the overall study	Conceived and designed the experiments	Methodology|Project administration	YES
5639739	29025408	NR	2	collected the data, carried out the analysis and wrote the manuscript	collected the data, carried out the analysis and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5639739	29025408	YL	2	designed, led and coordinated the overall study	designed, led and coordinated the overall study	Conceived and designed the experiments	Methodology|Project administration	YES
4414584	25923451	AM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414584	25923451	AM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414584	25923451	AM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414584	25923451	CJ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414584	25923451	CJ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414584	25923451	CJ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414584	25923451	JJ	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414584	25923451	JJ	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414584	25923451	JL	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414584	25923451	JL	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414584	25923451	KA	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414584	25923451	KA	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414584	25923451	KA	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414584	25923451	LN	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414584	25923451	LN	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414584	25923451	LN	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414584	25923451	MPB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414584	25923451	MPB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414584	25923451	MPB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5737097	29326735	All authors	2	carried out the field experiments and have read and approved this manuscript	carried out the field experiments and have read and approved this manuscript	Performed the experiments	Investigation	YES
5737097	29326735	JL	2	investigated the phenotypic data	investigated the phenotypic data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5737097	29326735	JT	2	conceived the research and improved the manuscript	conceived the research and improved the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5737097	29326735	QH	2	mapped the traits	mapped the traits	-	-	NO
5737097	29326735	WF	2	mapped the traits	mapped the traits	-	-	NO
5737097	29326735	YC	2	investigated the phenotypic data	investigated the phenotypic data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5737097	29326735	ZD	2	analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
1919420	17653285	JC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1919420	17653285	JC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1919420	17653285	JC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1919420	17653285	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1919420	17653285	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1919420	17653285	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1919420	17653285	KK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1919420	17653285	KK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1919420	17653285	KK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1919420	17653285	KK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1919420	17653285	RW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1919420	17653285	RW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1919420	17653285	RW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5093097	27807811	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5093097	27807811	EG	2	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5093097	27807811	HBS	2	conducted protein analysis experiments	conducted protein analysis experiments	Performed the experiments	Investigation	YES
5093097	27807811	JGCP	2	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5093097	27807811	JR	2	conducted protein analysis experiments	conducted protein analysis experiments	Performed the experiments	Investigation	YES
5093097	27807811	RAP	2	conceived and designed the study|drafted the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5093097	27807811	RAP	2	conceived and designed the study|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5093097	27807811	SDH	2	conducted protein analysis experiments	conducted protein analysis experiments	Performed the experiments	Investigation	YES
5093097	27807811	TMSB	2	conducted protein analysis experiments	conducted protein analysis experiments	Performed the experiments	Investigation	YES
5093097	27807811	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
4615858	26526790	Jingpei Long	2	contributed equally to this work	contributed equally to this work	-	-	NO
4615858	26526790	Zhiwei Ji	2	contributed equally to this work	contributed equally to this work	-	-	NO
3845396	24327805	Ambuj Kumar	2	equally contributed to this paper	equally contributed to this paper	-	-	NO
3845396	24327805	Vidya Rajendran	2	equally contributed to this paper	equally contributed to this paper	-	-	NO
6377692	30771019	AE	2	researched the data and contributed to, reviewed, and edited the manuscript	researched the data and contributed to, reviewed, and edited the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
6377692	30771019	IL	2	researched the data and contributed to, reviewed, and edited the manuscript	researched the data and contributed to, reviewed, and edited the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
6377692	30771019	IV	2	researched the data and wrote the manuscript	researched the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6377692	30771019	LJ	2	researched the data and contributed to, reviewed, and edited the manuscript	researched the data and contributed to, reviewed, and edited the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
6377692	30771019	MB	2	researched the data and contributed to, reviewed, and edited the manuscript	researched the data and contributed to, reviewed, and edited the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
6377692	30771019	MW	2	researched the data and contributed to, reviewed, and edited the manuscript	researched the data and contributed to, reviewed, and edited the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
6377692	30771019	OE	2	researched the data and wrote the manuscript|is the guarantor of this work and, as such, had full access to all the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis	researched the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6377692	30771019	OE	2	researched the data and wrote the manuscript|is the guarantor of this work and, as such, had full access to all the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis	is the guarantor of this work and, as such, had full access to all the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis	Analyzed the data	Data curation|Formal analysis	YES
6377692	30771019	OP	2	researched the data and contributed to, reviewed, and edited the manuscript	researched the data and contributed to, reviewed, and edited the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
6377692	30771019	PL	2	researched the data and contributed to, reviewed, and edited the manuscript	researched the data and contributed to, reviewed, and edited the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
6377692	30771019	SP	2	researched the data and contributed to, reviewed, and edited the manuscript	researched the data and contributed to, reviewed, and edited the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
6377692	30771019	TH	2	researched the data and contributed to, reviewed, and edited the manuscript	researched the data and contributed to, reviewed, and edited the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4414585	25923740	GG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414585	25923740	GG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414585	25923740	GG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414585	25923740	GG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414585	25923740	KH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414585	25923740	KH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414585	25923740	KH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414585	25923740	KH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414585	25923740	KH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414585	25923740	MK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414585	25923740	MK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414585	25923740	MK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414585	25923740	MU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414585	25923740	MU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414585	25923740	MU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414585	25923740	MU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414585	25923740	MU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414585	25923740	WB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414585	25923740	WB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414585	25923740	WB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5639745	29025409	AC	2	conducted the experiments	conducted the experiments	Performed the experiments	Investigation	YES
5639745	29025409	AJM	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5639745	29025409	All the authors	2	jointly conceived and designed the experiments and carried out the data analysis|reviewed and approved the final manuscript	jointly conceived and designed the experiments and carried out the data analysis	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
5639745	29025409	All the authors	2	jointly conceived and designed the experiments and carried out the data analysis|reviewed and approved the final manuscript	reviewed and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5639745	29025409	CMP-D	2	conducted the experiments	conducted the experiments	Performed the experiments	Investigation	YES
5639745	29025409	JMV	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5639745	29025409	MB	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5639745	29025409	MG-C	2	conducted the experiments|wrote the manuscript	conducted the experiments	Performed the experiments	Investigation	YES
5639745	29025409	MG-C	2	conducted the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5737139	29326732	CZ	2	designed experiment and supervised all the results, and contributed to writing the manuscript	designed experiment and supervised all the results, and contributed to writing the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Original Draft	YES
5737139	29326732	DG	2	helped with the figures and samples	helped with the figures and samples	-	Visualization	YES
5737139	29326732	DH	2	designed experiment and supervised all the results, and contributed to writing the manuscript	designed experiment and supervised all the results, and contributed to writing the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Original Draft	YES
5737139	29326732	LF	2	helped with the figures and samples	helped with the figures and samples	-	Visualization	YES
5737139	29326732	LZ	2	performed all the experimental measurements, analyzed the data, and drafted the manuscript	performed all the experimental measurements, analyzed the data, and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5737139	29326732	SW	2	helped with the figures and samples	helped with the figures and samples	-	Visualization	YES
5737139	29326732	XC	2	performed all the experimental measurements, analyzed the data, and drafted the manuscript	performed all the experimental measurements, analyzed the data, and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5737139	29326732	XY	2	performed all the experimental measurements, analyzed the data, and drafted the manuscript	performed all the experimental measurements, analyzed the data, and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5097060	27815917	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5097060	27815917	CL	2	co-wrote the manuscript	co-wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5097060	27815917	Cledir Santos	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5097060	27815917	MCD	2	analyzed data|co-wrote the manuscript	analyzed data	Analyzed the data	Formal analysis	YES
5097060	27815917	MCD	2	analyzed data|co-wrote the manuscript	co-wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5097060	27815917	Maria Cristina Diez	2	declare that they are inventors of a pending patent in chile using aspect of this work	declare that they are inventors of a pending patent in chile using aspect of this work	-	-	NO
5097060	27815917	NL	2	analyzed data|co-wrote the manuscript	analyzed data	Analyzed the data	Formal analysis	YES
5097060	27815917	NL	2	analyzed data|co-wrote the manuscript	co-wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5097060	27815917	Nelson Lima	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5097060	27815917	SE	2	conducted the experiments|co-wrote the manuscript	conducted the experiments	Performed the experiments	Investigation	YES
5097060	27815917	SE	2	conducted the experiments|co-wrote the manuscript	co-wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5097060	27815917	Sebastian Elgueta	2	declare that they are inventors of a pending patent in chile using aspect of this work	declare that they are inventors of a pending patent in chile using aspect of this work	-	-	NO
1919421	17653288	AV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1919421	17653288	AV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1919421	17653288	AV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1919421	17653288	AV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1919421	17653288	BW	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1919421	17653288	BW	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1919421	17653288	BW	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1919421	17653288	FM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1919421	17653288	FM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1919421	17653288	FM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1919421	17653288	FM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1919421	17653288	HS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1919421	17653288	HS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1919421	17653288	HS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1919421	17653288	MB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1919421	17653288	MB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1919421	17653288	MB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1919421	17653288	RS	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1919421	17653288	RS	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1919421	17653288	RS	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1919421	17653288	VG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1919421	17653288	VG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1919421	17653288	VG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1919421	17653288	VG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5639747	29025413	APS	2	conceived and designed the study|wrote the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5639747	29025413	APS	2	conceived and designed the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5639747	29025413	CAS	2	performed the data analysis|wrote the manuscript	performed the data analysis	Analyzed the data	Formal analysis	YES
5639747	29025413	CAS	2	performed the data analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5639747	29025413	JAFF	2	conceived and designed the study|performed the data analysis|wrote the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5639747	29025413	JAFF	2	conceived and designed the study|performed the data analysis|wrote the manuscript	performed the data analysis	Analyzed the data	Formal analysis	YES
5639747	29025413	JAFF	2	conceived and designed the study|performed the data analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5639747	29025413	LLB	2	performed the data analysis|wrote the manuscript	performed the data analysis	Analyzed the data	Formal analysis	YES
5639747	29025413	LLB	2	performed the data analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5639747	29025413	MACH	2	performed the data analysis|wrote the manuscript	performed the data analysis	Analyzed the data	Formal analysis	YES
5639747	29025413	MACH	2	performed the data analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6381199	30783791	CB	2	synthesized the radiotracers	synthesized the radiotracers	Performed the experiments	Investigation	YES
6381199	30783791	CD	2	were involved in the generation and characterization of the death-switch cell lines	were involved in the generation and characterization of the death-switch cell lines	Performed the experiments	Investigation	YES
6381199	30783791	CH	2	prepared the cells for tumour xenograft generation	prepared the cells for tumour xenograft generation	Performed the experiments	Investigation	YES
6381199	30783791	EOA	2	is the principal investigator and participated in the conception, design and coordination of the study	is the principal investigator and participated in the conception, design and coordination of the study	Conceived and designed the experiments	Conceptualization|Funding acquisition|Methodology|Project administration	YES
6381199	30783791	JH	2	were involved in the generation and characterization of the death-switch cell lines	were involved in the generation and characterization of the death-switch cell lines	Performed the experiments	Investigation	YES
6381199	30783791	KLS	2	were involved in the generation and characterization of the death-switch cell lines	were involved in the generation and characterization of the death-switch cell lines	Performed the experiments	Investigation	YES
6381199	30783791	LC	2	synthesized the radiotracers	synthesized the radiotracers	Performed the experiments	Investigation	YES
6381199	30783791	MMF	2	were involved in the generation and characterization of the death-switch cell lines	were involved in the generation and characterization of the death-switch cell lines	Performed the experiments	Investigation	YES
6381199	30783791	PET	2	imaging studies	imaging studies	Analyzed the data	Visualization	YES
6381199	30783791	SMS	2	carried out the in vitro studies and in vivo imaging experiments	carried out the in vitro studies and in vivo imaging experiments	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
6381199	30783791	TMI	2	were involved in the generation and characterization of the death-switch cell lines	were involved in the generation and characterization of the death-switch cell lines	Performed the experiments	Investigation	YES
6381199	30783791	VV	2	performed the in vivo biodistribution studies, all analyses and statistics and data interpretation and wrote the manuscript	performed the in vivo biodistribution studies, all analyses and statistics and data interpretation and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4615860	26526966	Marilia de Souza Dantas	2	contributed equally to this work	contributed equally to this work	-	-	NO
4414586	25922944	BFZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4414586	25922944	JSZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4414586	25922944	LXT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414586	25922944	LXT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414586	25922944	LXT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414586	25922944	LXT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414586	25922944	WM	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414586	25922944	WM	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414586	25922944	YXP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414586	25922944	YXP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414586	25922944	YXP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5741643	29326730	AB	2	designed experiments	designed experiments	Conceived and designed the experiments	Methodology	YES
5741643	29326730	All authors	2	contributed to the writing and revision of the manuscript	contributed to the writing and revision of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5741643	29326730	EJ	2	identified cyclotide genes from transcriptomic data	identified cyclotide genes from transcriptomic data	Performed the experiments	Investigation	YES
5741643	29326730	ID	2	designed experiments	designed experiments	Conceived and designed the experiments	Methodology	YES
5741643	29326730	K-OY	2	collected plant material for the transcriptome sequencing	collected plant material for the transcriptome sequencing	Performed the experiments	Investigation	YES
5741643	29326730	KJR	2	designed experiments	designed experiments	Conceived and designed the experiments	Methodology	YES
5741643	29326730	SP	2	designed experiments|carried out interpretation of precursor sequences, modeling and mass spectrometry|performed the phylogenetic analyses	designed experiments	Conceived and designed the experiments	Methodology	YES
5741643	29326730	SP	2	designed experiments|carried out interpretation of precursor sequences, modeling and mass spectrometry|performed the phylogenetic analyses	carried out interpretation of precursor sequences, modeling and mass spectrometry	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5741643	29326730	SP	2	designed experiments|carried out interpretation of precursor sequences, modeling and mass spectrometry|performed the phylogenetic analyses	performed the phylogenetic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5741643	29326730	TM	2	designed experiments|performed the phylogenetic analyses	designed experiments	Conceived and designed the experiments	Methodology	YES
5741643	29326730	TM	2	designed experiments|performed the phylogenetic analyses	performed the phylogenetic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5741643	29326730	UG	2	designed experiments|supervised the experiments	designed experiments	Conceived and designed the experiments	Methodology	YES
5741643	29326730	UG	2	designed experiments|supervised the experiments	supervised the experiments	-	Supervision	YES
5099301	27822898	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5099301	27822898	HDP	PLoS52	conceived the idea and designed the experiments|analyzed the data and wrote the manuscript	conceived the idea and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5099301	27822898	HDP	PLoS52	conceived the idea and designed the experiments|analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5099301	27822898	HJJ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5099301	27822898	SBL	PLoS52	conceived the idea and designed the experiments|performed the experiments|analyzed the data and wrote the manuscript	conceived the idea and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5099301	27822898	SBL	PLoS52	conceived the idea and designed the experiments|performed the experiments|analyzed the data and wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5099301	27822898	SBL	PLoS52	conceived the idea and designed the experiments|performed the experiments|analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5099301	27822898	SHY	PLoS52	conceived the idea and designed the experiments	conceived the idea and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5099301	27822898	The authors	PLoS52	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5099301	27822898	WSC	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
1919422	17653261	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1919422	17653261	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1919422	17653261	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1919422	17653261	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5639748	29025420	AM	2	made their contribution in data analyses and editing the manuscript	made their contribution in data analyses and editing the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
5639748	29025420	BA	2	made their contribution in data analyses and editing the manuscript	made their contribution in data analyses and editing the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
5639748	29025420	BD	2	made their contribution in data analyses and editing the manuscript	made their contribution in data analyses and editing the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
5639748	29025420	BTE	2	was responsible for data analyses and drafting the manuscript	was responsible for data analyses and drafting the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5639748	29025420	DW	2	made their contribution in data analyses and editing the manuscript	made their contribution in data analyses and editing the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
5639748	29025420	GA	2	made their contribution in data analyses and editing the manuscript	made their contribution in data analyses and editing the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
5639748	29025420	KS	2	supervised the design and analyses of the study and edited the manuscript	supervised the design and analyses of the study and edited the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Supervision|Writing - Review & Editing	YES
5639748	29025420	ML	2	made their contribution in data analyses and editing the manuscript	made their contribution in data analyses and editing the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
5639748	29025420	MO	2	made their contribution in data analyses and editing the manuscript	made their contribution in data analyses and editing the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
5639748	29025420	MW	2	made their contribution in data analyses and editing the manuscript	made their contribution in data analyses and editing the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
5639748	29025420	TC	2	made their contribution in data analyses and editing the manuscript	made their contribution in data analyses and editing the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
5639748	29025420	TK	2	made their contribution in data analyses and editing the manuscript	made their contribution in data analyses and editing the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
5639748	29025420	VO	2	made their contribution in data analyses and editing the manuscript	made their contribution in data analyses and editing the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
4414587	25923534	BS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414587	25923534	BS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414587	25923534	BS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414587	25923534	CG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414587	25923534	CG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414587	25923534	CG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414587	25923534	LH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414587	25923534	LH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414587	25923534	LH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414587	25923534	LH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414587	25923534	NR	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414587	25923534	NR	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414587	25923534	NR	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414587	25923534	NT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414587	25923534	NT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414587	25923534	NT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414587	25923534	NT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414587	25923534	SL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414587	25923534	SL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414587	25923534	SL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414587	25923534	SL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414587	25923534	SL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5741644	29326742	TS	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5741644	29326742	YP	PLoS52	performed the experiments and wrote the paper	performed the experiments and wrote the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5741644	29326742	YZ	PLoS52	designed the experiments and wrote the paper	designed the experiments and wrote the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
6382918	30788640	All authors	2	contributed to the study design and manuscript editing and review	contributed to the study design and manuscript editing and review	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
6382918	30788640	CMD	2	are the principal investigators of the research and have been involved in revising the manuscript critically for important intellectual content|scored the registration results	are the principal investigators of the research and have been involved in revising the manuscript critically for important intellectual content	Conceived and designed the experiments|Wrote the paper	Conceptualization|Funding acquisition|Writing - Review & Editing	YES
6382918	30788640	CMD	2	are the principal investigators of the research and have been involved in revising the manuscript critically for important intellectual content|scored the registration results	scored the registration results	-	-	NO
6382918	30788640	EJR	2	did the software development|was involved in the data collection, image analysis, statistical analysis, and drafting the manuscript	did the software development	Contributed reagents/materials/analysis tools	Software	YES
6382918	30788640	EJR	2	did the software development|was involved in the data collection, image analysis, statistical analysis, and drafting the manuscript	was involved in the data collection, image analysis, statistical analysis, and drafting the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Visualization|Writing - Original Draft	YES
6382918	30788640	GM	2	performed and analyzed the cbct scans	performed and analyzed the cbct scans	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6382918	30788640	JN	2	are the principal investigators of the research and have been involved in revising the manuscript critically for important intellectual content|did the software development	are the principal investigators of the research and have been involved in revising the manuscript critically for important intellectual content	Conceived and designed the experiments|Wrote the paper	Conceptualization|Funding acquisition|Writing - Review & Editing	YES
6382918	30788640	JN	2	are the principal investigators of the research and have been involved in revising the manuscript critically for important intellectual content|did the software development	did the software development	Contributed reagents/materials/analysis tools	Software	YES
6382918	30788640	KB	2	are the principal investigators of the research and have been involved in revising the manuscript critically for important intellectual content	are the principal investigators of the research and have been involved in revising the manuscript critically for important intellectual content	Conceived and designed the experiments|Wrote the paper	Conceptualization|Funding acquisition|Writing - Review & Editing	YES
6382918	30788640	WC	2	performed manual liver perfusion territory and liver segmentation	performed manual liver perfusion territory and liver segmentation	Performed the experiments	Investigation	YES
4414588	25924061	BZ	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414588	25924061	BZ	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414588	25924061	DB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414588	25924061	DB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414588	25924061	DB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414588	25924061	DB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414588	25924061	HZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414588	25924061	HZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414588	25924061	HZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414588	25924061	HZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414588	25924061	SL	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414588	25924061	SL	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5101243	27826948	JLS	1	Planning and designing of study	Planning and designing of study	Conceived and designed the experiments	Methodology	YES
5101243	27826948	JXC	1	Planning and designing of study	Planning and designing of study	Conceived and designed the experiments	Methodology	YES
5101243	27826948	YLL	1	Planning and designing of study	Planning and designing of study	Conceived and designed the experiments	Methodology	YES
3845628	24324375	Anne K. Mausberg	2	designed and performed the research, analyzed the data, and wrote the paper	designed and performed the research, analyzed the data, and wrote the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
3845628	24324375	Daniel Degrandi	2	performed the experiments and analysed data	performed the experiments and analysed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3845628	24324375	Felix P. Lubitz	2	performed the experiments, participated in the analysis of the data and the statistical analysis, and helped to draft the paper	performed the experiments, participated in the analysis of the data and the statistical analysis, and helped to draft the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3845628	24324375	Klaus Pfeffer	2	has revised the paper and was involved in study design	has revised the paper and was involved in study design	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
1919423	17653289	AC	1	Devised the screening strategy|Conducted the biochemical and cellular experiments, the microscopy analysis and the bioinformatics|Drafted the manuscript	Devised the screening strategy	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
1919423	17653289	AC	1	Devised the screening strategy|Conducted the biochemical and cellular experiments, the microscopy analysis and the bioinformatics|Drafted the manuscript	Conducted the biochemical and cellular experiments, the microscopy analysis and the bioinformatics	Performed the experiments	Formal analysis|Investigation	YES
1919423	17653289	AC	1	Devised the screening strategy|Conducted the biochemical and cellular experiments, the microscopy analysis and the bioinformatics|Drafted the manuscript	Drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
1919423	17653289	DB	1	Supported the dub cloning	Supported the dub cloning	Performed the experiments	Investigation	YES
1919423	17653289	EF	1	Devised the screening strategy|Supported the experimental approach|Helped draft the manuscript	Devised the screening strategy	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
1919423	17653289	EF	1	Devised the screening strategy|Supported the experimental approach|Helped draft the manuscript	Supported the experimental approach	-	-	NO
1919423	17653289	EF	1	Devised the screening strategy|Supported the experimental approach|Helped draft the manuscript	Helped draft the manuscript	Wrote the paper	Writing - Original Draft	YES
1919423	17653289	GK	1	Provided isopeptide-linked bait peptides	Provided isopeptide-linked bait peptides	Performed the experiments	Investigation	YES
1919423	17653289	PG	1	Supported the dub cloning	Supported the dub cloning	Performed the experiments	Investigation	YES
5639760	29025412	CM	2	carried out animal care, prepared samples and performed the experiments	carried out animal care, prepared samples and performed the experiments	Performed the experiments	Investigation	YES
5639760	29025412	LK	2	performed the data processing and biological information analysis	performed the data processing and biological information analysis	Analyzed the data	Data curation|Formal analysis	YES
5639760	29025412	YJ	2	designed and drafted the manuscript|conceived the study and the experimental design and helped draft the manuscript	designed and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
5639760	29025412	YJ	2	designed and drafted the manuscript|conceived the study and the experimental design and helped draft the manuscript	conceived the study and the experimental design and helped draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
5639760	29025412	YL	2	conceived the study and the experimental design and helped draft the manuscript	conceived the study and the experimental design and helped draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
5639760	29025412	YS	2	conceived the study and the experimental design and helped draft the manuscript	conceived the study and the experimental design and helped draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
5639760	29025412	YW	2	designed and drafted the manuscript|carried out animal care, prepared samples and performed the experiments|performed the data processing and biological information analysis	designed and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
5639760	29025412	YW	2	designed and drafted the manuscript|carried out animal care, prepared samples and performed the experiments|performed the data processing and biological information analysis	carried out animal care, prepared samples and performed the experiments	Performed the experiments	Investigation	YES
5639760	29025412	YW	2	designed and drafted the manuscript|carried out animal care, prepared samples and performed the experiments|performed the data processing and biological information analysis	performed the data processing and biological information analysis	Analyzed the data	Data curation|Formal analysis	YES
5741659	29326746	KS	2	performed most of the analysis and analyzed the data	performed most of the analysis and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5741659	29326746	NO	2	designed parts of the algorithm and helped with its implementation	designed parts of the algorithm and helped with its implementation	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5741659	29326746	RB	2	provided data and helped interpret the findings related to domestication	provided data and helped interpret the findings related to domestication	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5741659	29326746	The authors	2	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	Performed the experiments	Investigation	YES
5741659	29326746	ZN	2	conceived the project and wrote the article with	conceived the project and wrote the article with	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5741659	29326746	all authors	2	contributed with the conceived the project and wrote the article with	contributed with the conceived the project and wrote the article with	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4414589	25923362	CN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414589	25923362	CN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414589	25923362	CN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414589	25923362	CN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414589	25923362	ID	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414589	25923362	JDR	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414589	25923362	JDR	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414589	25923362	LPR	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
6384291	30790144	AD	2	contributed to the preparation of the study and of the revised manuscript	contributed to the preparation of the study and of the revised manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6384291	30790144	CLV	2	contributed to the preparation of the revised manuscript	contributed to the preparation of the revised manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6384291	30790144	DF	2	contributed to the preparation of the revised manuscript	contributed to the preparation of the revised manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6384291	30790144	MBe	2	contributed to the study design, phantom data collection, and analysis	contributed to the study design, phantom data collection, and analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Methodology|Resources	YES
6384291	30790144	MBi	2	contributed to the preparation of the revised manuscript	contributed to the preparation of the revised manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6384291	30790144	NB	2	contributed to the study design, data analysis, and writing of the original and revised manuscript	contributed to the study design, data analysis, and writing of the original and revised manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5101244	27826949	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5101244	27826949	CA	2	conceived, designed, and supervised the study, analyzed experimental data and wrote the manuscript	conceived, designed, and supervised the study, analyzed experimental data and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Supervision|Writing - Original Draft	YES
5101244	27826949	CB	2	designed and supervised the study	designed and supervised the study	Conceived and designed the experiments	Methodology|Supervision	YES
5101244	27826949	MS	2	designed and supervised the study	designed and supervised the study	Conceived and designed the experiments	Methodology|Supervision	YES
5101244	27826949	SH	2	designed and supervised the study	designed and supervised the study	Conceived and designed the experiments	Methodology|Supervision	YES
5101244	27826949	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5101244	27826949	Tossapol Limcharoensuk	2	for technical assistance	for technical assistance	Performed the experiments	Investigation	YES
5101244	27826949	YK	2	performed the experiments, analyzed experimental data and drafted the manuscript|designed and supervised the study	performed the experiments, analyzed experimental data and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5101244	27826949	YK	2	performed the experiments, analyzed experimental data and drafted the manuscript|designed and supervised the study	designed and supervised the study	Conceived and designed the experiments	Methodology|Supervision	YES
1919424	17653274	AD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1919424	17653274	AD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1919424	17653274	AD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1919424	17653274	AD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1919424	17653274	AV	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1919424	17653274	AV	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1919424	17653274	CC	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1919424	17653274	CC	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1919424	17653274	CC	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1919424	17653274	CG	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1919424	17653274	CG	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1919424	17653274	DR	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1919424	17653274	DR	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1919424	17653274	DR	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1919424	17653274	FM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1919424	17653274	FM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1919424	17653274	FM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1919424	17653274	FM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1919424	17653274	FS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1919424	17653274	FS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1919424	17653274	GC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1919424	17653274	GC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1919424	17653274	JB	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1919424	17653274	JB	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1919424	17653274	JF	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1919424	17653274	JF	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1919424	17653274	LP	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1919424	17653274	LP	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1919424	17653274	PC	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1919424	17653274	PC	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1919424	17653274	YL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1919424	17653274	YL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1919424	17653274	YL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5639766	29025393	ACT	2	designed fig	designed fig	Conceived and designed the experiments	-	YES
5639766	29025393	AD	2	designed the study|interpreted the results	designed the study	Conceived and designed the experiments	Methodology	YES
5639766	29025393	AD	2	designed the study|interpreted the results	interpreted the results	Analyzed the data	Formal analysis	YES
5639766	29025393	BR	2	contributed to analytic tools	contributed to analytic tools	Contributed reagents/materials/analysis tools	Resources	YES
5639766	29025393	GD	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5639766	29025393	HC	2	designed the study|interpreted the results	designed the study	Conceived and designed the experiments	Methodology	YES
5639766	29025393	HC	2	designed the study|interpreted the results	interpreted the results	Analyzed the data	Formal analysis	YES
5639766	29025393	KA	2	designed the study|interpreted the results|wrote the draft and the different authors contribute to its corrections	designed the study	Conceived and designed the experiments	Methodology	YES
5639766	29025393	KA	2	designed the study|interpreted the results|wrote the draft and the different authors contribute to its corrections	interpreted the results	Analyzed the data	Formal analysis	YES
5639766	29025393	KA	2	designed the study|interpreted the results|wrote the draft and the different authors contribute to its corrections	wrote the draft and the different authors contribute to its corrections	Wrote the paper	Writing - Original Draft	YES
5639766	29025393	NS	2	designed the study|generated the data|interpreted the results|wrote the draft and the different authors contribute to its corrections	designed the study	Conceived and designed the experiments	Methodology	YES
5639766	29025393	NS	2	designed the study|generated the data|interpreted the results|wrote the draft and the different authors contribute to its corrections	generated the data	Performed the experiments	Investigation	YES
5639766	29025393	NS	2	designed the study|generated the data|interpreted the results|wrote the draft and the different authors contribute to its corrections	interpreted the results	Analyzed the data	Formal analysis	YES
5639766	29025393	NS	2	designed the study|generated the data|interpreted the results|wrote the draft and the different authors contribute to its corrections	wrote the draft and the different authors contribute to its corrections	Wrote the paper	Writing - Original Draft	YES
5639766	29025393	OF	2	designed the study|contributed to analytic tools|interpreted the results	designed the study	Conceived and designed the experiments	Methodology	YES
5639766	29025393	OF	2	designed the study|contributed to analytic tools|interpreted the results	contributed to analytic tools	Contributed reagents/materials/analysis tools	Resources	YES
5639766	29025393	OF	2	designed the study|contributed to analytic tools|interpreted the results	interpreted the results	Analyzed the data	Formal analysis	YES
5639766	29025393	RA	2	designed the study|performed the population genetic analyses|interpreted the results|wrote the draft and the different authors contribute to its corrections	designed the study	Conceived and designed the experiments	Methodology	YES
5639766	29025393	RA	2	designed the study|performed the population genetic analyses|interpreted the results|wrote the draft and the different authors contribute to its corrections	performed the population genetic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5639766	29025393	RA	2	designed the study|performed the population genetic analyses|interpreted the results|wrote the draft and the different authors contribute to its corrections	interpreted the results	Analyzed the data	Formal analysis	YES
5639766	29025393	RA	2	designed the study|performed the population genetic analyses|interpreted the results|wrote the draft and the different authors contribute to its corrections	wrote the draft and the different authors contribute to its corrections	Wrote the paper	Writing - Original Draft	YES
5639766	29025393	YV	2	designed the study|interpreted the results|wrote the draft and the different authors contribute to its corrections	designed the study	Conceived and designed the experiments	Methodology	YES
5639766	29025393	YV	2	designed the study|interpreted the results|wrote the draft and the different authors contribute to its corrections	interpreted the results	Analyzed the data	Formal analysis	YES
5639766	29025393	YV	2	designed the study|interpreted the results|wrote the draft and the different authors contribute to its corrections	wrote the draft and the different authors contribute to its corrections	Wrote the paper	Writing - Original Draft	YES
4528079	26248959	James Ford	2	conceptualized the project, contributed to community-based research collaborations, contributed to interpretation of results, and contributed to manuscript writing	conceptualized the project, contributed to community-based research collaborations, contributed to interpretation of results, and contributed to manuscript writing	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
4528079	26248959	Kaitlin Patterson	2	contributed to data cleaning and analyses	contributed to data cleaning and analyses	Analyzed the data	Data curation|Formal analysis	YES
4528079	26248959	Lea Berrang-Ford	2	conceptualized the project, co-designed the questionnaires, co-supervised analyses, contributed to interpretation of results, and contributed to manuscript writing	conceptualized the project, co-designed the questionnaires, co-supervised analyses, contributed to interpretation of results, and contributed to manuscript writing	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Supervision|Writing - Original Draft	YES
4528079	26248959	Marie-Pierre Lardeau	2	contributed to analyses and interpretation of results, as well as manuscript editing	contributed to analyses and interpretation of results, as well as manuscript editing	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4528079	26248959	Sherilee Harper	2	co-designed the questionnaires, contributed to community-based research collaborations, led data collection, co-supervised data analyses and contributed to manuscript editing	co-designed the questionnaires, contributed to community-based research collaborations, led data collection, co-supervised data analyses and contributed to manuscript editing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Supervision|Writing - Review & Editing	YES
4528079	26248959	Victoria Edge	2	contributed to community-based research collaborations, contributed to planning and facilitation of data collection, and contributed to manuscript editing	contributed to community-based research collaborations, contributed to planning and facilitation of data collection, and contributed to manuscript editing	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Methodology|Resources|Writing - Review & Editing	YES
4528079	26248959	Yang Guo	2	co-analyzed data, interpreted results, prepared the primary manuscript draft, and led the editing	co-analyzed data, interpreted results, prepared the primary manuscript draft, and led the editing	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
4414590	25923722	CFC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414590	25923722	CFC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414590	25923722	CFC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414590	25923722	FHC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414590	25923722	FHC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414590	25923722	FHC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414590	25923722	FHC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414590	25923722	FHC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414590	25923722	MHC	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414590	25923722	MHC	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6386759	30796555	AK	2	performed the histopathological analysis	performed the histopathological analysis	Performed the experiments	Investigation	YES
6386759	30796555	AL	2	established the orthotopic rat model	established the orthotopic rat model	Performed the experiments	Methodology	YES
6386759	30796555	DP	2	established the orthotopic rat model|also performed surgical implantation of the orthopic tumors	established the orthotopic rat model	Performed the experiments	Methodology	YES
6386759	30796555	DP	2	established the orthotopic rat model|also performed surgical implantation of the orthopic tumors	also performed surgical implantation of the orthopic tumors	Performed the experiments	Investigation	YES
6386759	30796555	EK	2	optimized the mri sequence, performed mri acquisitions, analyzed the mri data, and were the major contributors in designing the experiments and the manuscript	optimized the mri sequence, performed mri acquisitions, analyzed the mri data, and were the major contributors in designing the experiments and the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
6386759	30796555	GM	2	contributed great input to adapt the mri sequences and supported with technical problems	contributed great input to adapt the mri sequences and supported with technical problems	Performed the experiments	Investigation	YES
6386759	30796555	IGS	2	supervised the statistical analysis	supervised the statistical analysis	Analyzed the data	Formal analysis|Supervision	YES
6386759	30796555	IMS	2	was involved in the establishment of the orthotopic rat model	was involved in the establishment of the orthotopic rat model	Performed the experiments	Methodology	YES
6386759	30796555	JA	2	optimized the mri sequence, performed mri acquisitions, analyzed the mri data, and were the major contributors in designing the experiments and the manuscript	optimized the mri sequence, performed mri acquisitions, analyzed the mri data, and were the major contributors in designing the experiments and the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
6386759	30796555	MB	2	contributed great input to adapt the mri sequences and supported with technical problems	contributed great input to adapt the mri sequences and supported with technical problems	Performed the experiments	Investigation	YES
6386759	30796555	NB	2	assisted with the animal experiments and animal welfare	assisted with the animal experiments and animal welfare	Performed the experiments	Investigation	YES
6386759	30796555	WB	2	contributed greatly to the writing of the manuscript and data analysis	contributed greatly to the writing of the manuscript and data analysis	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
1919425	17653263	AP	PLoS5	Analyzed the data|Reviewed manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
1919425	17653263	AP	PLoS5	Analyzed the data|Reviewed manuscript	Reviewed manuscript	Wrote the paper	Writing - Review & Editing	YES
1919425	17653263	CQ	PLoS5	Analyzed the data|Reviewed manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
1919425	17653263	CQ	PLoS5	Analyzed the data|Reviewed manuscript	Reviewed manuscript	Wrote the paper	Writing - Review & Editing	YES
1919425	17653263	FB	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Reviewed manuscript	Performed the experiments	Performed the experiments	Investigation	YES
1919425	17653263	FB	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Reviewed manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1919425	17653263	FB	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Reviewed manuscript	Reviewed manuscript	Wrote the paper	Writing - Review & Editing	YES
1919425	17653263	OA	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1919425	17653263	OA	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1919425	17653263	OA	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1919425	17653263	RF	PLoS5	Analyzed the data|Reviewed manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
1919425	17653263	RF	PLoS5	Analyzed the data|Reviewed manuscript	Reviewed manuscript	Wrote the paper	Writing - Review & Editing	YES
5102985	27830497	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5102985	27830497	HW	PLoS52	performed the experiments|performed the experiments|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5102985	27830497	HW	PLoS52	performed the experiments|performed the experiments|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5102985	27830497	HW	PLoS52	performed the experiments|performed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5102985	27830497	KW	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5102985	27830497	KY	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5102985	27830497	LL	PLoS52	revised the paper	revised the paper	Wrote the paper	Writing - Review & Editing	YES
5102985	27830497	ZC	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5102985	27830497	ZL	PLoS52	conceived and designed the experiments|contributed reagents/materials/analysis tools	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5102985	27830497	ZL	PLoS52	conceived and designed the experiments|contributed reagents/materials/analysis tools	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5742127	29312387	AP	PLoS52	analyzed the data|led the writing of the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5742127	29312387	AP	PLoS52	analyzed the data|led the writing of the manuscript	led the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5742127	29312387	All authors	PLoS52	contributed critically to the drafts and gave final approval for publication	contributed critically to the drafts and gave final approval for publication	Wrote the paper	Writing - Original Draft	YES
5742127	29312387	AvdW	PLoS52	conceived the ideas and designed methodology	conceived the ideas and designed methodology	Conceived and designed the experiments|Performed the experiments	Conceptualization|Methodology	YES
5742127	29312387	CR	PLoS52	collected the data	collected the data	Performed the experiments	Investigation	YES
5742127	29312387	H-KM	PLoS52	conceived the ideas and designed methodology|collected the data|analyzed the data|led the writing of the manuscript	conceived the ideas and designed methodology	Conceived and designed the experiments|Performed the experiments	Conceptualization|Methodology	YES
5742127	29312387	H-KM	PLoS52	conceived the ideas and designed methodology|collected the data|analyzed the data|led the writing of the manuscript	collected the data	Performed the experiments	Investigation	YES
5742127	29312387	H-KM	PLoS52	conceived the ideas and designed methodology|collected the data|analyzed the data|led the writing of the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5742127	29312387	H-KM	PLoS52	conceived the ideas and designed methodology|collected the data|analyzed the data|led the writing of the manuscript	led the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5742127	29312387	TMB	PLoS52	conceived the ideas and designed methodology|collected the data|analyzed the data|led the writing of the manuscript	conceived the ideas and designed methodology	Conceived and designed the experiments|Performed the experiments	Conceptualization|Methodology	YES
5742127	29312387	TMB	PLoS52	conceived the ideas and designed methodology|collected the data|analyzed the data|led the writing of the manuscript	collected the data	Performed the experiments	Investigation	YES
5742127	29312387	TMB	PLoS52	conceived the ideas and designed methodology|collected the data|analyzed the data|led the writing of the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5742127	29312387	TMB	PLoS52	conceived the ideas and designed methodology|collected the data|analyzed the data|led the writing of the manuscript	led the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5639768	29025389	DYZ	PLoS52	conducted rna extraction	conducted rna extraction	Performed the experiments	Investigation	YES
5639768	29025389	JX	PLoS52	supervised the experiments	supervised the experiments	-	Supervision	YES
5639768	29025389	KW	PLoS52	helped with rna seq sequencing	helped with rna seq sequencing	Performed the experiments	Investigation	YES
5639768	29025389	WLZ	PLoS52	conceived and designed the study|interpreted the results|wrote the paper	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5639768	29025389	WLZ	PLoS52	conceived and designed the study|interpreted the results|wrote the paper	interpreted the results	Analyzed the data	Formal analysis	YES
5639768	29025389	WLZ	PLoS52	conceived and designed the study|interpreted the results|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5639768	29025389	XCP	PLoS52	performed the rna seq, chip-seq and qpcr validation experiments|interpreted the results	performed the rna seq, chip-seq and qpcr validation experiments	Performed the experiments	Investigation|Validation	YES
5639768	29025389	XCP	PLoS52	performed the rna seq, chip-seq and qpcr validation experiments|interpreted the results	interpreted the results	Analyzed the data	Formal analysis	YES
5639768	29025389	XMY	PLoS52	helped to perform ir experiments	helped to perform ir experiments	Performed the experiments	Investigation	YES
5639768	29025389	XW	PLoS52	supervised the experiments	supervised the experiments	-	Supervision	YES
5639768	29025389	YF	PLoS52	analyzed all the data sets|interpreted the results	analyzed all the data sets	Analyzed the data	Formal analysis	YES
5639768	29025389	YF	PLoS52	analyzed all the data sets|interpreted the results	interpreted the results	Analyzed the data	Formal analysis	YES
3845728	24324371	Bernhard Schaller	2	helped write the paper and approved the final paper	helped write the paper and approved the final paper	Wrote the paper	Writing - Original Draft	YES
3845728	24324371	Jayesh Daya	2	edited and revised the paper and approved the final paper	edited and revised the paper and approved the final paper	Wrote the paper	Writing - Review & Editing	YES
3845728	24324371	Nora Sandu	2	edited and revised the paper and approved the final paper	edited and revised the paper and approved the final paper	Wrote the paper	Writing - Review & Editing	YES
3845728	24324371	Ronald B. Cappellani	2	helped in designing and writing the paper and approved the final paper	helped in designing and writing the paper and approved the final paper	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
3845728	24324371	Tumul Chowdhury	2	is responsible for data acquisition, data interpretation, drafting and writing the paper|approved the final paper	is responsible for data acquisition, data interpretation, drafting and writing the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3845728	24324371	Tumul Chowdhury	2	is responsible for data acquisition, data interpretation, drafting and writing the paper|approved the final paper	approved the final paper	-	-	NO
4414591	25923430	CWG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4414591	25923430	CYG	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414591	25923430	CYG	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4414591	25923430	DFC	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414591	25923430	FJL	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4414591	25923430	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414591	25923430	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414591	25923430	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414591	25923430	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414591	25923430	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414591	25923430	KL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414591	25923430	KL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414591	25923430	KL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414591	25923430	TL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4414591	25923430	UB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4414591	25923430	YS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
6391509	30806836	IM	4	Drafting of the manuscript and revisions were performed by|Final approval and submission of the manuscript was performed by	Drafting of the manuscript and revisions were performed by	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
6391509	30806836	IM	4	Drafting of the manuscript and revisions were performed by|Final approval and submission of the manuscript was performed by	Final approval and submission of the manuscript was performed by	Performed the experiments	Investigation	YES
6391509	30806836	IO	4	and data interpretation were performed by	and data interpretation were performed by	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6391509	30806836	MN	4	Final approval and submission of the manuscript was performed by	Final approval and submission of the manuscript was performed by	Performed the experiments	Investigation	YES
6391509	30806836	MT	4	and data interpretation were performed by	and data interpretation were performed by	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6391509	30806836	NO	4	and data interpretation were performed by|Drafting of the manuscript and revisions were performed by	and data interpretation were performed by	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6391509	30806836	NO	4	and data interpretation were performed by|Drafting of the manuscript and revisions were performed by	Drafting of the manuscript and revisions were performed by	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
6391509	30806836	ST	4	and data interpretation were performed by	and data interpretation were performed by	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
1919426	17653265	AB	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1919426	17653265	AB	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1919426	17653265	DB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1919426	17653265	DB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1919426	17653265	JJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1919426	17653265	JJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1919426	17653265	JJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1919426	17653265	JJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1919426	17653265	JJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1919426	17653265	JL	PLoS5	Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1919426	17653265	JL	PLoS5	Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1919426	17653265	JL	PLoS5	Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1919426	17653265	JL	PLoS5	Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1919426	17653265	MC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1919426	17653265	RS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1919426	17653265	TS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1919426	17653265	WH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1919426	17653265	WH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1919426	17653265	WH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1919426	17653265	XW	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1919426	17653265	XW	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4414592	25923788	CHC	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414592	25923788	CHC	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414592	25923788	CLZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414592	25923788	CLZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414592	25923788	CLZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414592	25923788	CLZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414592	25923788	CLZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414592	25923788	EG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414592	25923788	EG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414592	25923788	EG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414592	25923788	EG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414592	25923788	EG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414592	25923788	JTCL	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414592	25923788	MJM	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414592	25923788	MJM	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414592	25923788	NOL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414592	25923788	NOL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414592	25923788	NOL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414592	25923788	SAF	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4414592	25923788	SF	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4414592	25923788	SR	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4414592	25923788	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414592	25923788	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414592	25923788	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414592	25923788	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414592	25923788	SSG	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414592	25923788	SSG	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5102987	27830496	TL	PLoS5	Performed the experiments|Analyzed the data and contributed reagents|Writing the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
5102987	27830496	TL	PLoS5	Performed the experiments|Analyzed the data and contributed reagents|Writing the manuscript	Analyzed the data and contributed reagents	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5102987	27830496	TL	PLoS5	Performed the experiments|Analyzed the data and contributed reagents|Writing the manuscript	Writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5102987	27830496	XN	PLoS5	Performed the experiments|Analyzed the data and contributed reagents|Writing the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
5102987	27830496	XN	PLoS5	Performed the experiments|Analyzed the data and contributed reagents|Writing the manuscript	Analyzed the data and contributed reagents	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5102987	27830496	XN	PLoS5	Performed the experiments|Analyzed the data and contributed reagents|Writing the manuscript	Writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5102987	27830496	ZL	PLoS5	The main experimental conception and design|Analyzed the data and contributed reagents	The main experimental conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5102987	27830496	ZL	PLoS5	The main experimental conception and design|Analyzed the data and contributed reagents	Analyzed the data and contributed reagents	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5640929	29029602	All authors	2	contributed to editing and revising the manuscript	contributed to editing and revising the manuscript	Wrote the paper	Writing - Review & Editing	YES
5640929	29029602	KA	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5640929	29029602	MT	2	managed the computer resources	managed the computer resources	Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5640929	29029602	NK	2	designed and performed all experiments and analysed the data|wrote the manuscript	designed and performed all experiments and analysed the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5640929	29029602	NK	2	designed and performed all experiments and analysed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5742152	29312395	C-FZ	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5742152	29312395	C-FZ	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5742152	29312395	J-DR	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5742152	29312395	LZ	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5742152	29312395	LZ	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5742152	29312395	LZ	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5742152	29312395	SL	PLoS52	conceived and designed the experiments|analyzed the data|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5742152	29312395	SL	PLoS52	conceived and designed the experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5742152	29312395	SL	PLoS52	conceived and designed the experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5742152	29312395	X-QH	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5742152	29312395	X-QH	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5742152	29312395	X-QH	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5742152	29312395	ZZ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
4617876	26636099	All authors	2	have been involved in drafting the paper or revising it critically for important intellectual content and have given final approval of the version to be published	have been involved in drafting the paper or revising it critically for important intellectual content and have given final approval of the version to be published	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4617876	26636099	G. M. Marullo	2	conceived the paper	conceived the paper	Conceived and designed the experiments	Conceptualization	YES
6399366	30830508	All authors	2	performed aorta delineations and/or contributed to the final manuscript	performed aorta delineations and/or contributed to the final manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
6399366	30830508	FH	2	designed the study, performed the data evaluation, and wrote the manuscript|share first authorship	designed the study, performed the data evaluation, and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
6399366	30830508	FH	2	designed the study, performed the data evaluation, and wrote the manuscript|share first authorship	share first authorship	-	-	NO
6399366	30830508	JM	2	designed the study, performed the data evaluation, and wrote the manuscript|share first authorship	designed the study, performed the data evaluation, and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
6399366	30830508	JM	2	designed the study, performed the data evaluation, and wrote the manuscript|share first authorship	share first authorship	-	-	NO
6399366	30830508	JvdH	2	designed the study, performed the data evaluation, and wrote the manuscript	designed the study, performed the data evaluation, and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
1919427	17653259	AK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1919427	17653259	BC	PLoS5	Performed the experiments|Wrote the paper|Recruited patients	Performed the experiments	Performed the experiments	Investigation	YES
1919427	17653259	BC	PLoS5	Performed the experiments|Wrote the paper|Recruited patients	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1919427	17653259	BC	PLoS5	Performed the experiments|Wrote the paper|Recruited patients	Recruited patients	Performed the experiments	Investigation	YES
1919427	17653259	DC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Recruited patients	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1919427	17653259	DC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Recruited patients	Performed the experiments	Performed the experiments	Investigation	YES
1919427	17653259	DC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Recruited patients	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1919427	17653259	DC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Recruited patients	Recruited patients	Performed the experiments	Investigation	YES
1919427	17653259	DK	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1919427	17653259	DK	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1919427	17653259	DS	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Recruited patients	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1919427	17653259	DS	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Recruited patients	Performed the experiments	Performed the experiments	Investigation	YES
1919427	17653259	DS	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Recruited patients	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1919427	17653259	DS	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Recruited patients	Recruited patients	Performed the experiments	Investigation	YES
1919427	17653259	JM	PLoS5	Conceived and designed the experiments|Recruited patients	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1919427	17653259	JM	PLoS5	Conceived and designed the experiments|Recruited patients	Recruited patients	Performed the experiments	Investigation	YES
1919427	17653259	SE	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Recruited patients	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1919427	17653259	SE	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Recruited patients	Analyzed the data	Analyzed the data	Formal analysis	YES
1919427	17653259	SE	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Recruited patients	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1919427	17653259	SE	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Recruited patients	Recruited patients	Performed the experiments	Investigation	YES
5103005	27830495	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5103005	27830495	HH	2	wrote and revised the manuscript	wrote and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5103005	27830495	JBY	2	wrote and revised the manuscript	wrote and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5103005	27830495	QH	2	conceived experiments|carried out the experiments|performed the statistical analysis	conceived experiments	Conceived and designed the experiments	Conceptualization	YES
5103005	27830495	QH	2	conceived experiments|carried out the experiments|performed the statistical analysis	carried out the experiments	Performed the experiments	Investigation	YES
5103005	27830495	QH	2	conceived experiments|carried out the experiments|performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
5103005	27830495	RZ	2	conceived experiments|carried out the experiments	conceived experiments	Conceived and designed the experiments	Conceptualization	YES
5103005	27830495	RZ	2	conceived experiments|carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5103005	27830495	XYY	2	performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
5103005	27830495	ZHY	2	conceived experiments|wrote and revised the manuscript	conceived experiments	Conceived and designed the experiments	Conceptualization	YES
5103005	27830495	ZHY	2	conceived experiments|wrote and revised the manuscript	wrote and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5103005	27830495	ZWG	2	wrote and revised the manuscript	wrote and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4414593	25923237	BMK	PLoS5	Performed the experiments|Analyzed the data|Analyzed the data and agreed with the final version of the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4414593	25923237	BMK	PLoS5	Performed the experiments|Analyzed the data|Analyzed the data and agreed with the final version of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4414593	25923237	BMK	PLoS5	Performed the experiments|Analyzed the data|Analyzed the data and agreed with the final version of the manuscript	Analyzed the data and agreed with the final version of the manuscript	Analyzed the data	Formal analysis	YES
4414593	25923237	DRM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Analyzed the data and agreed with the final version of the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414593	25923237	DRM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Analyzed the data and agreed with the final version of the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4414593	25923237	DRM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Analyzed the data and agreed with the final version of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4414593	25923237	DRM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Analyzed the data and agreed with the final version of the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414593	25923237	DRM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Analyzed the data and agreed with the final version of the manuscript	Analyzed the data and agreed with the final version of the manuscript	Analyzed the data	Formal analysis	YES
4414593	25923237	SC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Analyzed the data and agreed with the final version of the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4414593	25923237	SC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Analyzed the data and agreed with the final version of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4414593	25923237	SC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Analyzed the data and agreed with the final version of the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414593	25923237	SC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Analyzed the data and agreed with the final version of the manuscript	Analyzed the data and agreed with the final version of the manuscript	Analyzed the data	Formal analysis	YES
4414593	25923237	SKM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Analyzed the data and agreed with the final version of the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414593	25923237	SKM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Analyzed the data and agreed with the final version of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4414593	25923237	SKM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Analyzed the data and agreed with the final version of the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414593	25923237	SKM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Analyzed the data and agreed with the final version of the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414593	25923237	SKM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Analyzed the data and agreed with the final version of the manuscript	Analyzed the data and agreed with the final version of the manuscript	Analyzed the data	Formal analysis	YES
5640933	29029611	Both authors	2	interpreted the results and wrote the manuscript	interpreted the results and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5640933	29029611	SL	2	conducted the computational, genetic and biochemical analyses	conducted the computational, genetic and biochemical analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
1919428	17653287	DL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1919428	17653287	DL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1919428	17653287	DL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1919428	17653287	FB	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1919428	17653287	FB	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1919428	17653287	JP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1919428	17653287	JP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1919428	17653287	JP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6419652	30868318	DSW	2	retrieved the data|analyzed and interpreted the data|wrote the manuscript	retrieved the data	-	-	NO
6419652	30868318	DSW	2	retrieved the data|analyzed and interpreted the data|wrote the manuscript	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
6419652	30868318	DSW	2	retrieved the data|analyzed and interpreted the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6419652	30868318	EHJGA	2	designed the study|analyzed and interpreted the data|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
6419652	30868318	EHJGA	2	designed the study|analyzed and interpreted the data|wrote the manuscript	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
6419652	30868318	EHJGA	2	designed the study|analyzed and interpreted the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6419652	30868318	EMMS	2	retrieved the data|analyzed and interpreted the data|wrote the manuscript	retrieved the data	-	-	NO
6419652	30868318	EMMS	2	retrieved the data|analyzed and interpreted the data|wrote the manuscript	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
6419652	30868318	EMMS	2	retrieved the data|analyzed and interpreted the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6419652	30868318	JJH	2	interpreted and analyzed the scans	interpreted and analyzed the scans	Analyzed the data	Formal analysis	YES
6419652	30868318	KvL	2	interpreted and analyzed the scans	interpreted and analyzed the scans	Analyzed the data	Formal analysis	YES
6419652	30868318	LFdGO	2	interpreted and analyzed the scans	interpreted and analyzed the scans	Analyzed the data	Formal analysis	YES
6419652	30868318	MG	2	designed the study|analyzed and interpreted the data	designed the study	Conceived and designed the experiments	Methodology	YES
6419652	30868318	MG	2	designed the study|analyzed and interpreted the data	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
6419652	30868318	WG	2	analyzed and interpreted the data	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
4618119	26558261	Tao Yu	2	contributed equally to this study	contributed equally to this study	-	-	NO
4618119	26558261	Zhengfei Yang	2	contributed equally to this study	contributed equally to this study	-	-	NO
5104702	27832517	AKP	2	collected the samples, performed the experiments, analyzed the data, and wrote the paper	collected the samples, performed the experiments, analyzed the data, and wrote the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5104702	27832517	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5104702	27832517	NSK	2	critically analyzed the study and helped in drafting the article as well as edited the manuscript	critically analyzed the study and helped in drafting the article as well as edited the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5104702	27832517	SDM	2	helped in performing the experiments and analyzed the data	helped in performing the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5104702	27832517	SPS	2	critically analyzed the study and helped in drafting the article as well as edited the manuscript	critically analyzed the study and helped in drafting the article as well as edited the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5104702	27832517	State Biotech Hub	2	to mizoram university	to mizoram university	-	-	NO
5640959	29029607	BJ	2	carried out the design of the study and drafted the manuscript|revised the manuscript	carried out the design of the study and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5640959	29029607	BJ	2	carried out the design of the study and drafted the manuscript|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5640959	29029607	JWC	2	participated in sample collection, rna extraction, quantitative rt pcr and data analysis	participated in sample collection, rna extraction, quantitative rt pcr and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5640959	29029607	JX	2	participated in sample collection, rna extraction, quantitative rt pcr and data analysis	participated in sample collection, rna extraction, quantitative rt pcr and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5640959	29029607	LW	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5640959	29029607	LZ	2	carried out the design of the study and drafted the manuscript|performed the experimental work and data analysis|participated in sample collection, rna extraction, quantitative rt pcr and data analysis|revised the manuscript	carried out the design of the study and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5640959	29029607	LZ	2	carried out the design of the study and drafted the manuscript|performed the experimental work and data analysis|participated in sample collection, rna extraction, quantitative rt pcr and data analysis|revised the manuscript	performed the experimental work and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5640959	29029607	LZ	2	carried out the design of the study and drafted the manuscript|performed the experimental work and data analysis|participated in sample collection, rna extraction, quantitative rt pcr and data analysis|revised the manuscript	participated in sample collection, rna extraction, quantitative rt pcr and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5640959	29029607	LZ	2	carried out the design of the study and drafted the manuscript|performed the experimental work and data analysis|participated in sample collection, rna extraction, quantitative rt pcr and data analysis|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5640959	29029607	WXL	2	carried out the design of the study and drafted the manuscript|participated in sample collection, rna extraction, quantitative rt pcr and data analysis|revised the manuscript	carried out the design of the study and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5640959	29029607	WXL	2	carried out the design of the study and drafted the manuscript|participated in sample collection, rna extraction, quantitative rt pcr and data analysis|revised the manuscript	participated in sample collection, rna extraction, quantitative rt pcr and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5640959	29029607	WXL	2	carried out the design of the study and drafted the manuscript|participated in sample collection, rna extraction, quantitative rt pcr and data analysis|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5640959	29029607	ZCH	2	performed the experimental work and data analysis|participated in sample collection, rna extraction, quantitative rt pcr and data analysis|revised the manuscript	performed the experimental work and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5640959	29029607	ZCH	2	performed the experimental work and data analysis|participated in sample collection, rna extraction, quantitative rt pcr and data analysis|revised the manuscript	participated in sample collection, rna extraction, quantitative rt pcr and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5640959	29029607	ZCH	2	performed the experimental work and data analysis|participated in sample collection, rna extraction, quantitative rt pcr and data analysis|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5640959	29029607	ZGL	2	participated in sample collection, rna extraction, quantitative rt pcr and data analysis	participated in sample collection, rna extraction, quantitative rt pcr and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5742156	29312401	BG	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
5742156	29312401	BG	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5742156	29312401	GH	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
5742156	29312401	GH	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5742156	29312401	HL-K	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5742156	29312401	JQ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5742156	29312401	JY	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
5742156	29312401	JY	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
5742156	29312401	JY	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5742156	29312401	WS	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5742156	29312401	WS	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5742156	29312401	YT	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4414594	25923696	HGB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414594	25923696	HGB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414594	25923696	HGB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414594	25923696	HGB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414594	25923696	HGB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414594	25923696	JLS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414594	25923696	JLS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414594	25923696	JLS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414594	25923696	JLS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414594	25923696	JLS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1919429	17653266	CW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1919429	17653266	CW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1919429	17653266	CW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1919429	17653266	CW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1919429	17653266	GM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1919429	17653266	GM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1919429	17653266	GM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1919429	17653266	ND	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1919429	17653266	ND	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1919429	17653266	PB	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1919429	17653266	PB	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4618120	26636102	Alessandro Moro Daniele	2	has performed all the statistical analysis and also analyzed the results	has performed all the statistical analysis and also analyzed the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4618120	26636102	Andreina Lafori	2	collaborated in the data analysis and in the writing of the paper and then approved the final version of the paper	collaborated in the data analysis and in the writing of the paper and then approved the final version of the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4618120	26636102	Cervelli Mario Romandini	2	has performed all the statistical analysis and also analyzed the results	has performed all the statistical analysis and also analyzed the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4618120	26636102	Claudio Vicini	2	collaborated with polysomnography evaluation, to improve and adapt the test at adult population, revised the paper, and then approved its final version	collaborated with polysomnography evaluation, to improve and adapt the test at adult population, revised the paper, and then approved its final version	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4618120	26636102	Fabrizio Salamanca Giovanni	2	collaborated with polysomnography evaluation, revised the paper, and then approved its final version	collaborated with polysomnography evaluation, revised the paper, and then approved its final version	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4618120	26636102	Giulio Gasparini	2	invented the test	invented the test	-	-	NO
4618120	26636102	Michele De Benedetto	2	collaborated with polysomnography evaluation, revised the paper, and then approved its final version	collaborated with polysomnography evaluation, revised the paper, and then approved its final version	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4618120	26636102	Sorrenti Enrico Foresta	2	collaborated with polysomnography evaluation, revised the paper, and then approved its final version	collaborated with polysomnography evaluation, revised the paper, and then approved its final version	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
6423188	30887136	D.M.	2	has carried out the immunohistochemistry and western blot analysis|have analyzed and interpreted the results|have approved the manuscript	has carried out the immunohistochemistry and western blot analysis	Performed the experiments	Investigation	YES
6423188	30887136	D.M.	2	has carried out the immunohistochemistry and western blot analysis|have analyzed and interpreted the results|have approved the manuscript	have analyzed and interpreted the results	Analyzed the data	Formal analysis	YES
6423188	30887136	D.M.	2	has carried out the immunohistochemistry and western blot analysis|have analyzed and interpreted the results|have approved the manuscript	have approved the manuscript	-	-	NO
6423188	30887136	K.D.	2	was responsible for the conception, design, and analysis and interpretation of data|have analyzed and interpreted the results|was responsible for writing the manuscript|have approved the manuscript	was responsible for the conception, design, and analysis and interpretation of data	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
6423188	30887136	K.D.	2	was responsible for the conception, design, and analysis and interpretation of data|have analyzed and interpreted the results|was responsible for writing the manuscript|have approved the manuscript	have analyzed and interpreted the results	Analyzed the data	Formal analysis	YES
6423188	30887136	K.D.	2	was responsible for the conception, design, and analysis and interpretation of data|have analyzed and interpreted the results|was responsible for writing the manuscript|have approved the manuscript	was responsible for writing the manuscript	Wrote the paper	Writing - Original Draft	YES
6423188	30887136	K.D.	2	was responsible for the conception, design, and analysis and interpretation of data|have analyzed and interpreted the results|was responsible for writing the manuscript|have approved the manuscript	have approved the manuscript	-	-	NO
6423188	30887136	S.G.	2	assisted in in vivo animal imaging experiments|have approved the manuscript	assisted in in vivo animal imaging experiments	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
6423188	30887136	S.G.	2	assisted in in vivo animal imaging experiments|have approved the manuscript	have approved the manuscript	-	-	NO
6423188	30887136	S.S.	2	assisted in in vivo animal imaging experiments|have approved the manuscript	assisted in in vivo animal imaging experiments	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
6423188	30887136	S.S.	2	assisted in in vivo animal imaging experiments|have approved the manuscript	have approved the manuscript	-	-	NO
5106418	27837549	All	2	authors read and approved the final manuscript	authors read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5106418	27837549	JU	2	manuscript drafting|authors read and approved the final manuscript	manuscript drafting	Wrote the paper	Writing - Original Draft	YES
5106418	27837549	JU	2	manuscript drafting|authors read and approved the final manuscript	authors read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5106418	27837549	YES	2	manuscript drafting	manuscript drafting	Wrote the paper	Writing - Original Draft	YES
5106418	27837549	YHK	2	authors read and approved the final manuscript	authors read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5742160	29312386	All authors	2	read, reviewed, and approved the final manuscript	read, reviewed, and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5742160	29312386	BG	2	partially revised the manuscript	partially revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5742160	29312386	QZ	2	conceived and designed the research|collected samples, generated experimental data, performed the entire data analysis, and drafted earlier versions of the manuscript	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5742160	29312386	QZ	2	conceived and designed the research|collected samples, generated experimental data, performed the entire data analysis, and drafted earlier versions of the manuscript	collected samples, generated experimental data, performed the entire data analysis, and drafted earlier versions of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5742160	29312386	TL	2	was involved in the sample collection	was involved in the sample collection	Performed the experiments	Investigation	YES
5742160	29312386	XX	2	conceived and designed the research	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5742160	29312386	ZZ	2	partially revised the manuscript|was involved in the sample collection	partially revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5742160	29312386	ZZ	2	partially revised the manuscript|was involved in the sample collection	was involved in the sample collection	Performed the experiments	Investigation	YES
6424988	30888521	KN	2	contributed to the analysis of the clinical data and collected the phantom data for calculating the calibration factors	contributed to the analysis of the clinical data and collected the phantom data for calculating the calibration factors	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
6424988	30888521	MJ	2	contributed to the study design and critically revised the manuscript	contributed to the study design and critically revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
6424988	30888521	TN	2	contributed to the study design, analyzed the data, and drafted and critically revised the manuscript	contributed to the study design, analyzed the data, and drafted and critically revised the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
6424988	30888521	TS	2	contributed to the analysis of the clinical data and collected the phantom data for calculating the calibration factors	contributed to the analysis of the clinical data and collected the phantom data for calculating the calibration factors	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
6424988	30888521	YO	2	contributed to the study design, analyzed the data, and drafted and critically revised the manuscript	contributed to the study design, analyzed the data, and drafted and critically revised the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5644071	29037146	HKT	PLoS52	designed the analyses|wrote the paper|is the principal investigator	designed the analyses	Conceived and designed the experiments|Analyzed the data	Formal analysis	YES
5644071	29037146	HKT	PLoS52	designed the analyses|wrote the paper|is the principal investigator	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5644071	29037146	HKT	PLoS52	designed the analyses|wrote the paper|is the principal investigator	is the principal investigator	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
5644071	29037146	WHL	PLoS52	designed the analyses|collected the data and performed the analyses|wrote the paper	designed the analyses	Conceived and designed the experiments|Analyzed the data	Formal analysis	YES
5644071	29037146	WHL	PLoS52	designed the analyses|collected the data and performed the analyses|wrote the paper	collected the data and performed the analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5644071	29037146	WHL	PLoS52	designed the analyses|collected the data and performed the analyses|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5644071	29037146	ZTYT	PLoS52	designed the analyses|wrote the paper	designed the analyses	Conceived and designed the experiments|Analyzed the data	Formal analysis	YES
5644071	29037146	ZTYT	PLoS52	designed the analyses|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
1919430	17653267	AW	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1919430	17653267	AW	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1919430	17653267	DP	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1919430	17653267	JG	PLoS5	Provided guidance|Contributed to analyzes|Edited the manuscript	Provided guidance	-	Supervision	YES
1919430	17653267	JG	PLoS5	Provided guidance|Contributed to analyzes|Edited the manuscript	Contributed to analyzes	Analyzed the data	Formal analysis	YES
1919430	17653267	JG	PLoS5	Provided guidance|Contributed to analyzes|Edited the manuscript	Edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
1919430	17653267	LB	PLoS5	Provided guidance|Edited the manuscript	Provided guidance	-	Supervision	YES
1919430	17653267	LB	PLoS5	Provided guidance|Edited the manuscript	Edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
1919430	17653267	PH	PLoS5	Contributed to editing	Contributed to editing	Wrote the paper	Writing - Review & Editing	YES
1919430	17653267	VC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1919430	17653267	VC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1919430	17653267	VC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1919430	17653267	VC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5742162	29312398	DB	2	conceived the idea and contributed to experimental design	conceived the idea and contributed to experimental design	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
5742162	29312398	MS	2	contributed to experimental design and carried out aphid experimental work, overall data analysis, and writing of the manuscript	contributed to experimental design and carried out aphid experimental work, overall data analysis, and writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
5742162	29312398	TH	2	conceived the idea and contributed to experimental design|carried out whitefly experimental work and contributed to interpretation of results and writing of the manuscript	conceived the idea and contributed to experimental design	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
5742162	29312398	TH	2	conceived the idea and contributed to experimental design|carried out whitefly experimental work and contributed to interpretation of results and writing of the manuscript	carried out whitefly experimental work and contributed to interpretation of results and writing of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5108735	27844458	AGN	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5108735	27844458	All authors	2	read and approved the manuscript|have declared that they have no competing interests	read and approved the manuscript	-	-	NO
5108735	27844458	All authors	2	read and approved the manuscript|have declared that they have no competing interests	have declared that they have no competing interests	-	-	NO
5108735	27844458	KDS	2	directed and designed experiments	directed and designed experiments	Conceived and designed the experiments	Methodology|Supervision	YES
5108735	27844458	NRD	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5108735	27844458	PTG	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5108735	27844458	SRW	2	directed and designed experiments	directed and designed experiments	Conceived and designed the experiments	Methodology|Supervision	YES
5108735	27844458	SVA	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
4414595	25923665	AP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414595	25923665	AP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414595	25923665	AP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414595	25923665	AP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414595	25923665	AP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414595	25923665	FAMV	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414595	25923665	FAMV	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414595	25923665	FAMV	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414595	25923665	JS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414595	25923665	JS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414595	25923665	JS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414595	25923665	JS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414595	25923665	MPMV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414595	25923665	MPMV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414595	25923665	MPMV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414595	25923665	MPMV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414595	25923665	MPMV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414595	25923665	MVS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414595	25923665	MVS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414595	25923665	MVS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414595	25923665	MVS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414595	25923665	MVS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414595	25923665	TH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414595	25923665	TH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414595	25923665	TH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6424990	30888559	AM	2	contributed to drafting of the manuscript together	contributed to drafting of the manuscript together	Wrote the paper	Writing - Original Draft	YES
6424990	30888559	HO	2	designed the study|contributed to data acquisition|contributed to the data analysis and interpretation|performed the statistical analysis|contributed to drafting of the manuscript together	designed the study	Conceived and designed the experiments	Methodology	YES
6424990	30888559	HO	2	designed the study|contributed to data acquisition|contributed to the data analysis and interpretation|performed the statistical analysis|contributed to drafting of the manuscript together	contributed to data acquisition	Performed the experiments	Investigation	YES
6424990	30888559	HO	2	designed the study|contributed to data acquisition|contributed to the data analysis and interpretation|performed the statistical analysis|contributed to drafting of the manuscript together	contributed to the data analysis and interpretation	Analyzed the data	Formal analysis	YES
6424990	30888559	HO	2	designed the study|contributed to data acquisition|contributed to the data analysis and interpretation|performed the statistical analysis|contributed to drafting of the manuscript together	performed the statistical analysis	Analyzed the data	Formal analysis	YES
6424990	30888559	HO	2	designed the study|contributed to data acquisition|contributed to the data analysis and interpretation|performed the statistical analysis|contributed to drafting of the manuscript together	contributed to drafting of the manuscript together	Wrote the paper	Writing - Original Draft	YES
6424990	30888559	KK	2	contributed to drafting of the manuscript together	contributed to drafting of the manuscript together	Wrote the paper	Writing - Original Draft	YES
6424990	30888559	TM	2	contributed to data acquisition	contributed to data acquisition	Performed the experiments	Investigation	YES
6424990	30888559	TT	2	contributed to data acquisition|contributed to the data analysis and interpretation|performed the statistical analysis|contributed to drafting of the manuscript together	contributed to data acquisition	Performed the experiments	Investigation	YES
6424990	30888559	TT	2	contributed to data acquisition|contributed to the data analysis and interpretation|performed the statistical analysis|contributed to drafting of the manuscript together	contributed to the data analysis and interpretation	Analyzed the data	Formal analysis	YES
6424990	30888559	TT	2	contributed to data acquisition|contributed to the data analysis and interpretation|performed the statistical analysis|contributed to drafting of the manuscript together	performed the statistical analysis	Analyzed the data	Formal analysis	YES
6424990	30888559	TT	2	contributed to data acquisition|contributed to the data analysis and interpretation|performed the statistical analysis|contributed to drafting of the manuscript together	contributed to drafting of the manuscript together	Wrote the paper	Writing - Original Draft	YES
6424990	30888559	YH	2	contributed to data acquisition|contributed to drafting of the manuscript together	contributed to data acquisition	Performed the experiments	Investigation	YES
6424990	30888559	YH	2	contributed to data acquisition|contributed to drafting of the manuscript together	contributed to drafting of the manuscript together	Wrote the paper	Writing - Original Draft	YES
6424990	30888559	YK	2	contributed to drafting of the manuscript together	contributed to drafting of the manuscript together	Wrote the paper	Writing - Original Draft	YES
1919431	17653268	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1919431	17653268	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1919431	17653268	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1919431	17653268	HA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1919431	17653268	HA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1919431	17653268	HA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1919431	17653268	JW	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Performed the experiments|Wrote the paper|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1919431	17653268	JW	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Performed the experiments|Wrote the paper|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1919431	17653268	JW	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Performed the experiments|Wrote the paper|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1919431	17653268	JW	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Performed the experiments|Wrote the paper|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1919431	17653268	JW	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Performed the experiments|Wrote the paper|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1919431	17653268	JW	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Performed the experiments|Wrote the paper|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1919431	17653268	LP	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1919431	17653268	LP	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1919431	17653268	LP	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1919431	17653268	SA	PLoS5	Performed the experiments|Performed the experiments|Performed the experiments|Wrote the paper|Wrote the paper|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1919431	17653268	SA	PLoS5	Performed the experiments|Performed the experiments|Performed the experiments|Wrote the paper|Wrote the paper|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1919431	17653268	SA	PLoS5	Performed the experiments|Performed the experiments|Performed the experiments|Wrote the paper|Wrote the paper|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1919431	17653268	SA	PLoS5	Performed the experiments|Performed the experiments|Performed the experiments|Wrote the paper|Wrote the paper|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1919431	17653268	SA	PLoS5	Performed the experiments|Performed the experiments|Performed the experiments|Wrote the paper|Wrote the paper|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1919431	17653268	SA	PLoS5	Performed the experiments|Performed the experiments|Performed the experiments|Wrote the paper|Wrote the paper|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1919431	17653268	SJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1919431	17653268	SJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1919431	17653268	SJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1919431	17653268	SJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1919431	17653268	YF	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1919431	17653268	YF	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5644092	29037173	All authors	2	participated in writing and approved the final version of the manuscript	participated in writing and approved the final version of the manuscript	Wrote the paper	Writing - Original Draft	YES
5644092	29037173	JB	2	provided expertise on protists and the eukaryotic phylogeny|led and guided the study	provided expertise on protists and the eukaryotic phylogeny	-	-	NO
5644092	29037173	JB	2	provided expertise on protists and the eukaryotic phylogeny|led and guided the study	led and guided the study	-	Supervision	YES
5644092	29037173	LG	2	provided the first version of reference taxa	provided the first version of reference taxa	-	-	NO
5644092	29037173	NG	2	selected the taxa for the reference database and wrote the reference database section in the manuscript	selected the taxa for the reference database and wrote the reference database section in the manuscript	Contributed reagents/materials/analysis tools|Wrote the paper	Software|Writing - Original Draft	YES
5644092	29037173	SR	2	provided bioinformatics expertise and wrote sections of the manuscript|led and guided the study	provided bioinformatics expertise and wrote sections of the manuscript	Wrote the paper	Formal analysis|Writing - Original Draft	YES
5644092	29037173	SR	2	provided bioinformatics expertise and wrote sections of the manuscript|led and guided the study	led and guided the study	-	Supervision	YES
5108744	27844457	All	2	authors read and approved the final manuscript	authors read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5108744	27844457	JNB	2	authors read and approved the final manuscript	authors read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5108744	27844457	KV	2	executed the project	executed the project	Performed the experiments	Investigation	YES
6426909	30895393	All authors	PLoS52	contributed to the review and editing of the manuscript and approved the final manuscript	contributed to the review and editing of the manuscript and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6426909	30895393	BL	PLoS52	performed tissue sample processing|performed bioinformatic analyses and data visualization|analyzed and interpreted the data	performed tissue sample processing	Performed the experiments	Data curation|Investigation	YES
6426909	30895393	BL	PLoS52	performed tissue sample processing|performed bioinformatic analyses and data visualization|analyzed and interpreted the data	performed bioinformatic analyses and data visualization	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
6426909	30895393	BL	PLoS52	performed tissue sample processing|performed bioinformatic analyses and data visualization|analyzed and interpreted the data	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
6426909	30895393	BW	PLoS52	analyzed and interpreted the data|contributed reagents/materials/analysis tools	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
6426909	30895393	BW	PLoS52	analyzed and interpreted the data|contributed reagents/materials/analysis tools	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
6426909	30895393	EFA	PLoS52	conceived and designed the experiments|analyzed and interpreted the data|contributed reagents/materials/analysis tools|drafted the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6426909	30895393	EFA	PLoS52	conceived and designed the experiments|analyzed and interpreted the data|contributed reagents/materials/analysis tools|drafted the manuscript	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
6426909	30895393	EFA	PLoS52	conceived and designed the experiments|analyzed and interpreted the data|contributed reagents/materials/analysis tools|drafted the manuscript	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
6426909	30895393	EFA	PLoS52	conceived and designed the experiments|analyzed and interpreted the data|contributed reagents/materials/analysis tools|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
6426909	30895393	ES	PLoS52	performed tissue sample processing|analyzed and interpreted the data	performed tissue sample processing	Performed the experiments	Data curation|Investigation	YES
6426909	30895393	ES	PLoS52	performed tissue sample processing|analyzed and interpreted the data	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
6426909	30895393	JD	PLoS52	conceived and designed the experiments|performed the animal experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6426909	30895393	JD	PLoS52	conceived and designed the experiments|performed the animal experiments	performed the animal experiments	Performed the experiments	Investigation	YES
6426909	30895393	JS	PLoS52	conceived and designed the experiments|performed the animal experiments|performed tissue sample processing|performed bioinformatic analyses and data visualization|analyzed and interpreted the data|contributed reagents/materials/analysis tools|drafted the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6426909	30895393	JS	PLoS52	conceived and designed the experiments|performed the animal experiments|performed tissue sample processing|performed bioinformatic analyses and data visualization|analyzed and interpreted the data|contributed reagents/materials/analysis tools|drafted the manuscript	performed the animal experiments	Performed the experiments	Investigation	YES
6426909	30895393	JS	PLoS52	conceived and designed the experiments|performed the animal experiments|performed tissue sample processing|performed bioinformatic analyses and data visualization|analyzed and interpreted the data|contributed reagents/materials/analysis tools|drafted the manuscript	performed tissue sample processing	Performed the experiments	Data curation|Investigation	YES
6426909	30895393	JS	PLoS52	conceived and designed the experiments|performed the animal experiments|performed tissue sample processing|performed bioinformatic analyses and data visualization|analyzed and interpreted the data|contributed reagents/materials/analysis tools|drafted the manuscript	performed bioinformatic analyses and data visualization	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
6426909	30895393	JS	PLoS52	conceived and designed the experiments|performed the animal experiments|performed tissue sample processing|performed bioinformatic analyses and data visualization|analyzed and interpreted the data|contributed reagents/materials/analysis tools|drafted the manuscript	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
6426909	30895393	JS	PLoS52	conceived and designed the experiments|performed the animal experiments|performed tissue sample processing|performed bioinformatic analyses and data visualization|analyzed and interpreted the data|contributed reagents/materials/analysis tools|drafted the manuscript	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
6426909	30895393	JS	PLoS52	conceived and designed the experiments|performed the animal experiments|performed tissue sample processing|performed bioinformatic analyses and data visualization|analyzed and interpreted the data|contributed reagents/materials/analysis tools|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
6426909	30895393	KH	PLoS52	analyzed and interpreted the data|contributed reagents/materials/analysis tools	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
6426909	30895393	KH	PLoS52	analyzed and interpreted the data|contributed reagents/materials/analysis tools	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
6426909	30895393	NPR	PLoS52	performed tissue sample processing|performed bioinformatic analyses and data visualization|analyzed and interpreted the data	performed tissue sample processing	Performed the experiments	Data curation|Investigation	YES
6426909	30895393	NPR	PLoS52	performed tissue sample processing|performed bioinformatic analyses and data visualization|analyzed and interpreted the data	performed bioinformatic analyses and data visualization	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
6426909	30895393	NPR	PLoS52	performed tissue sample processing|performed bioinformatic analyses and data visualization|analyzed and interpreted the data	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
6426909	30895393	ON	PLoS52	analyzed and interpreted the data|contributed reagents/materials/analysis tools	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
6426909	30895393	ON	PLoS52	analyzed and interpreted the data|contributed reagents/materials/analysis tools	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
6426909	30895393	TZP	PLoS52	performed tissue sample processing|analyzed and interpreted the data	performed tissue sample processing	Performed the experiments	Data curation|Investigation	YES
6426909	30895393	TZP	PLoS52	performed tissue sample processing|analyzed and interpreted the data	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5742209	29312399	BH	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5742209	29312399	LL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5742209	29312399	LZ	PLoS5	Carried out the experiments|Contributed reagents/materials/analysis tools	Carried out the experiments	Performed the experiments	Investigation	YES
5742209	29312399	LZ	PLoS5	Carried out the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5742209	29312399	MY	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5742209	29312399	PC	PLoS5	Created and designed the experiments|Carried out the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Created and designed the experiments	Conceived and designed the experiments	Methodology	YES
5742209	29312399	PC	PLoS5	Created and designed the experiments|Carried out the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Carried out the experiments	Performed the experiments	Investigation	YES
5742209	29312399	PC	PLoS5	Created and designed the experiments|Carried out the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5742209	29312399	PC	PLoS5	Created and designed the experiments|Carried out the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5742209	29312399	SA	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5742209	29312399	YQ	PLoS5	Created and designed the experiments|Wrote the paper	Created and designed the experiments	Conceived and designed the experiments	Methodology	YES
5742209	29312399	YQ	PLoS5	Created and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5742209	29312399	YaL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5742209	29312399	YiL	PLoS5	Created and designed the experiments|The analysis of data	Created and designed the experiments	Conceived and designed the experiments	Methodology	YES
5742209	29312399	YiL	PLoS5	Created and designed the experiments|The analysis of data	The analysis of data	Analyzed the data	Formal analysis	YES
5742209	29312399	ZH	PLoS5	Carried out the experiments|Contributed reagents/materials/analysis tools	Carried out the experiments	Performed the experiments	Investigation	YES
5742209	29312399	ZH	PLoS5	Carried out the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5742209	29312399	ZR	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5742209	29312399	ZZ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414596	25923694	GL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4414596	25923694	JPY	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414596	25923694	JXW	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4571579	26374468	All authors	2	have participated in the manuscript according to the criteria for authors	have participated in the manuscript according to the criteria for authors	-	-	NO
1919432	17653280	CR	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1919432	17653280	CR	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1919432	17653280	RG	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1919432	17653280	RG	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1919432	17653280	SJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1919432	17653280	SJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1919432	17653280	SJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6430261	30903403	AKOA	2	contributed to the treatment of living animals	contributed to the treatment of living animals	-	-	NO
6430261	30903403	All authors	2	have revised the manuscript critically for important intellectual content and given the final approval of the version to be published	have revised the manuscript critically for important intellectual content and given the final approval of the version to be published	Wrote the paper	Writing - Review & Editing	YES
6430261	30903403	Each author	2	has participated sufficiently in the work to take public responsibility for appropriate portions of the content and has agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	has participated sufficiently in the work to take public responsibility for appropriate portions of the content and has agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	-	-	NO
6430261	30903403	OLN	2	contributed to the histopathology and necropsy	contributed to the histopathology and necropsy	Performed the experiments	Investigation	YES
6430261	30903403	PA	2	contributed to the idea, design, necropsy, analysis of imaging, interpretation of data, statistics, and writing of the manuscript	contributed to the idea, design, necropsy, analysis of imaging, interpretation of data, statistics, and writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Resources|Visualization|Writing - Original Draft	YES
6430261	30903403	SBH	2	contributed to the modeling of the fdg data	contributed to the modeling of the fdg data	Performed the experiments|Contributed reagents/materials/analysis tools	Methodology|Resources	YES
5644099	29037144	All authors	2	wrote, read, and approved the final manuscript	wrote, read, and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5644099	29037144	CMP	2	developed the key idea|did all the experiments|analyzed the rna seq data	developed the key idea	Conceived and designed the experiments	Conceptualization	YES
5644099	29037144	CMP	2	developed the key idea|did all the experiments|analyzed the rna seq data	did all the experiments	Performed the experiments	Investigation	YES
5644099	29037144	CMP	2	developed the key idea|did all the experiments|analyzed the rna seq data	analyzed the rna seq data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5644099	29037144	DPP	2	developed the key idea	developed the key idea	Conceived and designed the experiments	Conceptualization	YES
5644099	29037144	MAK	2	developed the key idea	developed the key idea	Conceived and designed the experiments	Conceptualization	YES
5644099	29037144	RLK	2	did all the experiments|analyzed the rna seq data	did all the experiments	Performed the experiments	Investigation	YES
5644099	29037144	RLK	2	did all the experiments|analyzed the rna seq data	analyzed the rna seq data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5110461	27848233	AB	2	designed and carried out all experiments, analyzed the data, and drafted the manuscript	designed and carried out all experiments, analyzed the data, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5110461	27848233	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5110461	27848233	JN	2	conceived the study and revised the manuscript	conceived the study and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5110461	27848233	VS	2	assisted with the data analysis and revised the manuscript	assisted with the data analysis and revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5110461	27848233	YC	2	designed the research, assisted with the data analysis, and revised the manuscript	designed the research, assisted with the data analysis, and revised the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
1919433	17637835	CH	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1919433	17637835	JC	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1919433	17637835	JC	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1919433	17637835	JO	PLoS5	Analyzed the data|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1919433	17637835	JO	PLoS5	Analyzed the data|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1919433	17637835	ML	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1919433	17637835	ML	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1919433	17637835	ML	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1919433	17637835	MN	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1919433	17637835	MN	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1919433	17637835	MN	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1919433	17637835	MZ	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1919433	17637835	MZ	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5742226	29312396	DZ	2	co-designed and initiated this study, collated the plot data used in the analysis, contributed to integration and interpretation of the data, and contributed to the final manuscript	co-designed and initiated this study, collated the plot data used in the analysis, contributed to integration and interpretation of the data, and contributed to the final manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Data curation|Formal analysis|Methodology|Resources|Writing - Review & Editing	YES
5742226	29312396	EN	2	co-designed this study, contributed to statistical analysis and to integration, and interpretation of the results, and played a lead role in drafting the final manuscript	co-designed this study, contributed to statistical analysis and to integration, and interpretation of the results, and played a lead role in drafting the final manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5742226	29312396	MM	2	contributed to collation of the plot data used in the analysis, conducted and documented the bulk of the similarity and phylogenetic analyses, contributed to integration and interpretation of the results, and contributed to the final manuscript	contributed to collation of the plot data used in the analysis, conducted and documented the bulk of the similarity and phylogenetic analyses, contributed to integration and interpretation of the results, and contributed to the final manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Review & Editing	YES
5742226	29312396	TM	2	conducted statistical analysis, contributed to integration, visualization and interpretation of the results, also contributing toward the final manuscript	conducted statistical analysis, contributed to integration, visualization and interpretation of the results, also contributing toward the final manuscript	Analyzed the data|Wrote the paper	Formal analysis|Visualization|Writing - Review & Editing	YES
5112228	27854078	All	2	data is shown in graphs	data is shown in graphs	-	-	NO
5112228	27854078	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5112228	27854078	KK	2	assisted with the parameters and optimization problem solved by the sej took	assisted with the parameters and optimization problem solved by the sej took	-	-	NO
5112228	27854078	SEJ	2	parameters and optimization problem solved by the sej took	parameters and optimization problem solved by the sej took	-	-	NO
5112228	27854078	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
1919434	17653284	BB	PLoS5	Performed the experiments|Wrote the paper|Revised the manuscript|Contributed to the statistical design	Performed the experiments	Performed the experiments	Investigation	YES
1919434	17653284	BB	PLoS5	Performed the experiments|Wrote the paper|Revised the manuscript|Contributed to the statistical design	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1919434	17653284	BB	PLoS5	Performed the experiments|Wrote the paper|Revised the manuscript|Contributed to the statistical design	Revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
1919434	17653284	BB	PLoS5	Performed the experiments|Wrote the paper|Revised the manuscript|Contributed to the statistical design	Contributed to the statistical design	Conceived and designed the experiments|Analyzed the data	Formal analysis	YES
1919434	17653284	EA	PLoS5	Revised the manuscript|Collected samples and evaluated the patients	Revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
1919434	17653284	EA	PLoS5	Revised the manuscript|Collected samples and evaluated the patients	Collected samples and evaluated the patients	Performed the experiments	Investigation	YES
1919434	17653284	GJ	PLoS5	Analyzed the data|Revised the manuscript|Wrote the statistical sections in the manuscript|Contributed to the statistical design	Analyzed the data	Analyzed the data	Formal analysis	YES
1919434	17653284	GJ	PLoS5	Analyzed the data|Revised the manuscript|Wrote the statistical sections in the manuscript|Contributed to the statistical design	Revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
1919434	17653284	GJ	PLoS5	Analyzed the data|Revised the manuscript|Wrote the statistical sections in the manuscript|Contributed to the statistical design	Wrote the statistical sections in the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
1919434	17653284	GJ	PLoS5	Analyzed the data|Revised the manuscript|Wrote the statistical sections in the manuscript|Contributed to the statistical design	Contributed to the statistical design	Conceived and designed the experiments|Analyzed the data	Formal analysis	YES
1919434	17653284	IR	PLoS5	Revised the manuscript|Contributed to genotyping	Revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
1919434	17653284	IR	PLoS5	Revised the manuscript|Contributed to genotyping	Contributed to genotyping	Performed the experiments	Investigation	YES
1919434	17653284	JH	PLoS5	Conceived and designed the experiments|Contributed with reagents and samples|Revised the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1919434	17653284	JH	PLoS5	Conceived and designed the experiments|Contributed with reagents and samples|Revised the manuscript	Contributed with reagents and samples	Contributed reagents/materials/analysis tools	Resources	YES
1919434	17653284	JH	PLoS5	Conceived and designed the experiments|Contributed with reagents and samples|Revised the manuscript	Revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
1919434	17653284	JP	PLoS5	Contributed to the analysis of data|Wrote the statistical sections in the manuscript	Contributed to the analysis of data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
1919434	17653284	JP	PLoS5	Contributed to the analysis of data|Wrote the statistical sections in the manuscript	Wrote the statistical sections in the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
1919434	17653284	KD	PLoS5	Conceived and designed the experiments|Wrote the paper|Revised the manuscript|Contributed to the statistical design	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1919434	17653284	KD	PLoS5	Conceived and designed the experiments|Wrote the paper|Revised the manuscript|Contributed to the statistical design	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1919434	17653284	KD	PLoS5	Conceived and designed the experiments|Wrote the paper|Revised the manuscript|Contributed to the statistical design	Revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
1919434	17653284	KD	PLoS5	Conceived and designed the experiments|Wrote the paper|Revised the manuscript|Contributed to the statistical design	Contributed to the statistical design	Conceived and designed the experiments|Analyzed the data	Formal analysis	YES
5644110	29037147	EJ	2	provided materials and facilities	provided materials and facilities	Contributed reagents/materials/analysis tools	Resources	YES
5644110	29037147	HV	2	designed and performed individual experiments	designed and performed individual experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5644110	29037147	KS	2	designed and conceived the study|designed and performed individual experiments	designed and conceived the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5644110	29037147	KS	2	designed and conceived the study|designed and performed individual experiments	designed and performed individual experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5644110	29037147	LP	2	organized genome sequencing	organized genome sequencing	Performed the experiments	Investigation	YES
5644110	29037147	O-PS	2	assembled the genomes and participated in the bioinformatic analyses	assembled the genomes and participated in the bioinformatic analyses	Analyzed the data	Formal analysis	YES
5644110	29037147	PA	2	designed and conceived the study|provided materials and facilities	designed and conceived the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5644110	29037147	PA	2	designed and conceived the study|provided materials and facilities	provided materials and facilities	Contributed reagents/materials/analysis tools	Resources	YES
5644110	29037147	PD	2	designed and conceived the study|performed majority of the experiments	designed and conceived the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5644110	29037147	PD	2	designed and conceived the study|performed majority of the experiments	performed majority of the experiments	Performed the experiments	Investigation	YES
5644110	29037147	PKL	2	assembled the genomes and participated in the bioinformatic analyses	assembled the genomes and participated in the bioinformatic analyses	Analyzed the data	Formal analysis	YES
5644110	29037147	PV	2	designed and conceived the study|provided materials and facilities	designed and conceived the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5644110	29037147	PV	2	designed and conceived the study|provided materials and facilities	provided materials and facilities	Contributed reagents/materials/analysis tools	Resources	YES
5644110	29037147	RJR	2	designed and performed individual experiments	designed and performed individual experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5644110	29037147	VP	2	designed and conceived the study|provided materials and facilities	designed and conceived the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5644110	29037147	VP	2	designed and conceived the study|provided materials and facilities	provided materials and facilities	Contributed reagents/materials/analysis tools	Resources	YES
4414597	25922933	JH	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414597	25922933	MC	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414597	25922933	PR	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5742235	29312393	All authors	2	reviewed the results and approved the final version of the manuscript	reviewed the results and approved the final version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5742235	29312393	CA-L	2	contributed to the preparation of the figures, drafting and revision of the manuscript	contributed to the preparation of the figures, drafting and revision of the manuscript	Wrote the paper	Visualization|Writing - Original Draft|Writing - Review & Editing	YES
5742235	29312393	IJ	2	conceived and coordinated the study|designed, performed and analyzed the experiments|contributed to the preparation of the figures, drafting and revision of the manuscript|wrote the manuscript	conceived and coordinated the study	Conceived and designed the experiments	Conceptualization|Project administration	YES
5742235	29312393	IJ	2	conceived and coordinated the study|designed, performed and analyzed the experiments|contributed to the preparation of the figures, drafting and revision of the manuscript|wrote the manuscript	designed, performed and analyzed the experiments	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5742235	29312393	IJ	2	conceived and coordinated the study|designed, performed and analyzed the experiments|contributed to the preparation of the figures, drafting and revision of the manuscript|wrote the manuscript	contributed to the preparation of the figures, drafting and revision of the manuscript	Wrote the paper	Visualization|Writing - Original Draft|Writing - Review & Editing	YES
5742235	29312393	IJ	2	conceived and coordinated the study|designed, performed and analyzed the experiments|contributed to the preparation of the figures, drafting and revision of the manuscript|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5742235	29312393	LJ	2	designed, performed and analyzed the experiments|contributed to the preparation of the figures, drafting and revision of the manuscript	designed, performed and analyzed the experiments	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5742235	29312393	LJ	2	designed, performed and analyzed the experiments|contributed to the preparation of the figures, drafting and revision of the manuscript	contributed to the preparation of the figures, drafting and revision of the manuscript	Wrote the paper	Visualization|Writing - Original Draft|Writing - Review & Editing	YES
5742235	29312393	LM	2	designed, performed and analyzed the experiments|contributed to the preparation of the figures, drafting and revision of the manuscript	designed, performed and analyzed the experiments	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5742235	29312393	LM	2	designed, performed and analyzed the experiments|contributed to the preparation of the figures, drafting and revision of the manuscript	contributed to the preparation of the figures, drafting and revision of the manuscript	Wrote the paper	Visualization|Writing - Original Draft|Writing - Review & Editing	YES
5742235	29312393	SB	2	performed the modeling predictions|contributed to the preparation of the figures, drafting and revision of the manuscript	performed the modeling predictions	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5742235	29312393	SB	2	performed the modeling predictions|contributed to the preparation of the figures, drafting and revision of the manuscript	contributed to the preparation of the figures, drafting and revision of the manuscript	Wrote the paper	Visualization|Writing - Original Draft|Writing - Review & Editing	YES
6437225	30919133	AAL	2	contributed to the concept and design of the study|drafted the article|contributed to the data analysis|contributed to the interpretation of the data|read, critically reviewed, and approved the manuscript	contributed to the concept and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6437225	30919133	AAL	2	contributed to the concept and design of the study|drafted the article|contributed to the data analysis|contributed to the interpretation of the data|read, critically reviewed, and approved the manuscript	drafted the article	Wrote the paper	Writing - Original Draft	YES
6437225	30919133	AAL	2	contributed to the concept and design of the study|drafted the article|contributed to the data analysis|contributed to the interpretation of the data|read, critically reviewed, and approved the manuscript	contributed to the data analysis	Analyzed the data	Formal analysis	YES
6437225	30919133	AAL	2	contributed to the concept and design of the study|drafted the article|contributed to the data analysis|contributed to the interpretation of the data|read, critically reviewed, and approved the manuscript	contributed to the interpretation of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6437225	30919133	AAL	2	contributed to the concept and design of the study|drafted the article|contributed to the data analysis|contributed to the interpretation of the data|read, critically reviewed, and approved the manuscript	read, critically reviewed, and approved the manuscript	Wrote the paper	Writing - Review & Editing	YES
6437225	30919133	CF	2	provided the data|contributed to the interpretation of the data|read, critically reviewed, and approved the manuscript	provided the data	Contributed reagents/materials/analysis tools	Resources	YES
6437225	30919133	CF	2	provided the data|contributed to the interpretation of the data|read, critically reviewed, and approved the manuscript	contributed to the interpretation of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6437225	30919133	CF	2	provided the data|contributed to the interpretation of the data|read, critically reviewed, and approved the manuscript	read, critically reviewed, and approved the manuscript	Wrote the paper	Writing - Review & Editing	YES
6437225	30919133	FH	2	contributed to the concept and design of the study|drafted the article|contributed to the data analysis|contributed to the interpretation of the data|read, critically reviewed, and approved the manuscript	contributed to the concept and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6437225	30919133	FH	2	contributed to the concept and design of the study|drafted the article|contributed to the data analysis|contributed to the interpretation of the data|read, critically reviewed, and approved the manuscript	drafted the article	Wrote the paper	Writing - Original Draft	YES
6437225	30919133	FH	2	contributed to the concept and design of the study|drafted the article|contributed to the data analysis|contributed to the interpretation of the data|read, critically reviewed, and approved the manuscript	contributed to the data analysis	Analyzed the data	Formal analysis	YES
6437225	30919133	FH	2	contributed to the concept and design of the study|drafted the article|contributed to the data analysis|contributed to the interpretation of the data|read, critically reviewed, and approved the manuscript	contributed to the interpretation of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6437225	30919133	FH	2	contributed to the concept and design of the study|drafted the article|contributed to the data analysis|contributed to the interpretation of the data|read, critically reviewed, and approved the manuscript	read, critically reviewed, and approved the manuscript	Wrote the paper	Writing - Review & Editing	YES
6437225	30919133	HB	2	contributed to the data analysis|contributed to the interpretation of the data|read, critically reviewed, and approved the manuscript	contributed to the data analysis	Analyzed the data	Formal analysis	YES
6437225	30919133	HB	2	contributed to the data analysis|contributed to the interpretation of the data|read, critically reviewed, and approved the manuscript	contributed to the interpretation of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6437225	30919133	HB	2	contributed to the data analysis|contributed to the interpretation of the data|read, critically reviewed, and approved the manuscript	read, critically reviewed, and approved the manuscript	Wrote the paper	Writing - Review & Editing	YES
6437225	30919133	ILA	2	contributed to the concept and design of the study|drafted the article|contributed to the data analysis|contributed to the interpretation of the data|read, critically reviewed, and approved the manuscript	contributed to the concept and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6437225	30919133	ILA	2	contributed to the concept and design of the study|drafted the article|contributed to the data analysis|contributed to the interpretation of the data|read, critically reviewed, and approved the manuscript	drafted the article	Wrote the paper	Writing - Original Draft	YES
6437225	30919133	ILA	2	contributed to the concept and design of the study|drafted the article|contributed to the data analysis|contributed to the interpretation of the data|read, critically reviewed, and approved the manuscript	contributed to the data analysis	Analyzed the data	Formal analysis	YES
6437225	30919133	ILA	2	contributed to the concept and design of the study|drafted the article|contributed to the data analysis|contributed to the interpretation of the data|read, critically reviewed, and approved the manuscript	contributed to the interpretation of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6437225	30919133	ILA	2	contributed to the concept and design of the study|drafted the article|contributed to the data analysis|contributed to the interpretation of the data|read, critically reviewed, and approved the manuscript	read, critically reviewed, and approved the manuscript	Wrote the paper	Writing - Review & Editing	YES
6437225	30919133	JDG	2	contributed to the concept and design of the study|contributed to the interpretation of the data|read, critically reviewed, and approved the manuscript	contributed to the concept and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6437225	30919133	JDG	2	contributed to the concept and design of the study|contributed to the interpretation of the data|read, critically reviewed, and approved the manuscript	contributed to the interpretation of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6437225	30919133	JDG	2	contributed to the concept and design of the study|contributed to the interpretation of the data|read, critically reviewed, and approved the manuscript	read, critically reviewed, and approved the manuscript	Wrote the paper	Writing - Review & Editing	YES
6437225	30919133	KH	2	provided the data|contributed to the interpretation of the data|read, critically reviewed, and approved the manuscript	provided the data	Contributed reagents/materials/analysis tools	Resources	YES
6437225	30919133	KH	2	provided the data|contributed to the interpretation of the data|read, critically reviewed, and approved the manuscript	contributed to the interpretation of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6437225	30919133	KH	2	provided the data|contributed to the interpretation of the data|read, critically reviewed, and approved the manuscript	read, critically reviewed, and approved the manuscript	Wrote the paper	Writing - Review & Editing	YES
6437225	30919133	MY	2	contributed to the concept and design of the study|drafted the article|contributed to the data analysis|contributed to the interpretation of the data|read, critically reviewed, and approved the manuscript	contributed to the concept and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6437225	30919133	MY	2	contributed to the concept and design of the study|drafted the article|contributed to the data analysis|contributed to the interpretation of the data|read, critically reviewed, and approved the manuscript	drafted the article	Wrote the paper	Writing - Original Draft	YES
6437225	30919133	MY	2	contributed to the concept and design of the study|drafted the article|contributed to the data analysis|contributed to the interpretation of the data|read, critically reviewed, and approved the manuscript	contributed to the data analysis	Analyzed the data	Formal analysis	YES
6437225	30919133	MY	2	contributed to the concept and design of the study|drafted the article|contributed to the data analysis|contributed to the interpretation of the data|read, critically reviewed, and approved the manuscript	contributed to the interpretation of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6437225	30919133	MY	2	contributed to the concept and design of the study|drafted the article|contributed to the data analysis|contributed to the interpretation of the data|read, critically reviewed, and approved the manuscript	read, critically reviewed, and approved the manuscript	Wrote the paper	Writing - Review & Editing	YES
6437225	30919133	SB	2	provided the data|contributed to the interpretation of the data|read, critically reviewed, and approved the manuscript	provided the data	Contributed reagents/materials/analysis tools	Resources	YES
6437225	30919133	SB	2	provided the data|contributed to the interpretation of the data|read, critically reviewed, and approved the manuscript	contributed to the interpretation of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6437225	30919133	SB	2	provided the data|contributed to the interpretation of the data|read, critically reviewed, and approved the manuscript	read, critically reviewed, and approved the manuscript	Wrote the paper	Writing - Review & Editing	YES
1919467	17653277	CB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1919467	17653277	CB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1919467	17653277	CB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1919467	17653277	DB	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1919467	17653277	DB	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1919467	17653277	JS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1919467	17653277	JS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1919467	17653277	MM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1919467	17653277	MM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1919467	17653277	MM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1919467	17653277	MM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1919467	17653277	MM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1919467	17653277	VK	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1919467	17653277	VK	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4619757	26568955	Bing Wang	2	contribute equally to this study	contribute equally to this study	-	-	NO
4619757	26568955	Xiaoteng Yu	2	contribute equally to this study	contribute equally to this study	-	-	NO
5118231	27873164	AM	2	have conceived and designed experiments|have analyzed the data|have written the research paper	have conceived and designed experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5118231	27873164	AM	2	have conceived and designed experiments|have analyzed the data|have written the research paper	have analyzed the data	Analyzed the data	Formal analysis	YES
5118231	27873164	AM	2	have conceived and designed experiments|have analyzed the data|have written the research paper	have written the research paper	Wrote the paper	Writing - Original Draft	YES
5118231	27873164	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5118231	27873164	GR	2	have conceived and designed experiments|has performed the experiments|have analyzed the data|have written the research paper	have conceived and designed experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5118231	27873164	GR	2	have conceived and designed experiments|has performed the experiments|have analyzed the data|have written the research paper	has performed the experiments	Performed the experiments	Investigation	YES
5118231	27873164	GR	2	have conceived and designed experiments|has performed the experiments|have analyzed the data|have written the research paper	have analyzed the data	Analyzed the data	Formal analysis	YES
5118231	27873164	GR	2	have conceived and designed experiments|has performed the experiments|have analyzed the data|have written the research paper	have written the research paper	Wrote the paper	Writing - Original Draft	YES
5118231	27873164	GZ	2	have conceived and designed experiments	have conceived and designed experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5118231	27873164	WL	2	have contributed reagents/analysis tools	have contributed reagents/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5118231	27873164	XZ	2	have contributed reagents/analysis tools	have contributed reagents/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414598	25923440	BLK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414598	25923440	BLK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414598	25923440	BLK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414598	25923440	CE	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4414598	25923440	CE	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4414598	25923440	MLA	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414598	25923440	SG	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4414598	25923440	SG	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4414598	25923440	YX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414598	25923440	YX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4414598	25923440	YX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5644112	29037161	AF	2	helped idealizing the study, in discussing the results and in writing the manuscript	helped idealizing the study, in discussing the results and in writing the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5644112	29037161	CO	2	helped idealizing the study, in discussing the results and in writing the manuscript	helped idealizing the study, in discussing the results and in writing the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5644112	29037161	DB	2	reared all insects and completed larval performance studies	reared all insects and completed larval performance studies	Performed the experiments	Investigation	YES
5644112	29037161	KLSB	2	idealized the study, completed lab work, interpreted the data, prepared figures and wrote the manuscript	idealized the study, completed lab work, interpreted the data, prepared figures and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Visualization|Writing - Original Draft	YES
5644112	29037161	MMB	2	analyzed and annotated the transcriptome, and was a major contributor in idealizing the study and in writing the manuscript	analyzed and annotated the transcriptome, and was a major contributor in idealizing the study and in writing the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
5644112	29037161	RJH	2	reared all insects and completed larval performance studies	reared all insects and completed larval performance studies	Performed the experiments	Investigation	YES
5742236	29312405	KG	2	have made a substantial, direct and intellectual contribution to the work, and approved it for publication	have made a substantial, direct and intellectual contribution to the work, and approved it for publication	-	-	NO
5742236	29312405	PK	2	have made a substantial, direct and intellectual contribution to the work, and approved it for publication	have made a substantial, direct and intellectual contribution to the work, and approved it for publication	-	-	NO
6437247	30919091	ACC	2	critically revised the manuscript and improved the pharmacokinetic analysis pipeline	critically revised the manuscript and improved the pharmacokinetic analysis pipeline	Wrote the paper	Writing - Review & Editing	YES
6437247	30919091	CN	2	conceived, designed, or supervised the metabolic studies	conceived, designed, or supervised the metabolic studies	Conceived and designed the experiments	Conceptualization|Methodology|Supervision	YES
6437247	30919091	DPB	2	conceived, designed, or supervised the metabolic studies	conceived, designed, or supervised the metabolic studies	Conceived and designed the experiments	Conceptualization|Methodology|Supervision	YES
6437247	30919091	MAR	2	designed and implemented the pharmacokinetic analysis pipeline, performed data analysis, and drafted this paper|on the implementation of the pharmacokinetic pipeline	designed and implemented the pharmacokinetic analysis pipeline, performed data analysis, and drafted this paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6437247	30919091	MAR	2	designed and implemented the pharmacokinetic analysis pipeline, performed data analysis, and drafted this paper|on the implementation of the pharmacokinetic pipeline	on the implementation of the pharmacokinetic pipeline	Performed the experiments	Investigation	YES
6437247	30919091	ML	2	critically revised the manuscript and improved the pharmacokinetic analysis pipeline	critically revised the manuscript and improved the pharmacokinetic analysis pipeline	Wrote the paper	Writing - Review & Editing	YES
6437247	30919091	RL	2	critically revised the manuscript and improved the pharmacokinetic analysis pipeline	critically revised the manuscript and improved the pharmacokinetic analysis pipeline	Wrote the paper	Writing - Review & Editing	YES
1920549	17653260	IM	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1920549	17653260	IM	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1920549	17653260	SA	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1920549	17653260	SA	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5120163	27878569	YK	1	Contributed materials	Contributed materials	Contributed reagents/materials/analysis tools	Resources	YES
5120163	27878569	YU	1	Contributed materials	Contributed materials	Contributed reagents/materials/analysis tools	Resources	YES
4414599	25923713	ATM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414599	25923713	ATM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414599	25923713	ATM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414599	25923713	ATM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414599	25923713	FJR-D	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414599	25923713	FJRD	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414599	25923713	FJRD	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414599	25923713	FJRD	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414599	25923713	FJRD	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414599	25923713	SA	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4414599	25923713	SA	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4414599	25923713	VG	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4414599	25923713	VG	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4414599	25923713	VG	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414599	25923713	VSJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414599	25923713	VSJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414599	25923713	VSJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414599	25923713	VSJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5644125	29037158	MH	2	conceived and executed the study|wrote the manuscript	conceived and executed the study	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5644125	29037158	MH	2	conceived and executed the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5644125	29037158	MWH	2	conceived and executed the study|edited and proofed the manuscript	conceived and executed the study	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5644125	29037158	MWH	2	conceived and executed the study|edited and proofed the manuscript	edited and proofed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5742238	29312407	AS	2	helped writing the final manuscript and all authors approved the final manuscript	helped writing the final manuscript and all authors approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5742238	29312407	BG	2	helped writing the final manuscript and all authors approved the final manuscript	helped writing the final manuscript and all authors approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5742238	29312407	RS	2	helped writing the final manuscript and all authors approved the final manuscript	helped writing the final manuscript and all authors approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5742238	29312407	SC	2	did the literature research, drafted the manuscript and made tables	did the literature research, drafted the manuscript and made tables	Wrote the paper	Formal analysis|Writing - Original Draft	YES
5742238	29312407	The authors	2	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	Performed the experiments	Investigation	YES
4626370	26514282	A-KSK	2	drafted the first version of the manuscript|contributed equally to this work	drafted the first version of the manuscript	Wrote the paper	Writing - Original Draft	YES
4626370	26514282	A-KSK	2	drafted the first version of the manuscript|contributed equally to this work	contributed equally to this work	-	-	NO
4626370	26514282	A-SH	2	drafted the first version of the manuscript|contributed equally to this work	drafted the first version of the manuscript	Wrote the paper	Writing - Original Draft	YES
4626370	26514282	A-SH	2	drafted the first version of the manuscript|contributed equally to this work	contributed equally to this work	-	-	NO
4626370	26514282	All authors	2	participated in the acquisition of statistical data and revised the manuscript for important intellectual content	participated in the acquisition of statistical data and revised the manuscript for important intellectual content	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
4414600	25923806	HD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414600	25923806	HD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414600	25923806	HD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414600	25923806	IN	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414600	25923806	IN	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414600	25923806	IP	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414600	25923806	IP	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5120169	27878568	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5120169	27878568	HS	2	supervised the research and revised the manuscript	supervised the research and revised the manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
5120169	27878568	JBVL	2	supervised the research and revised the manuscript	supervised the research and revised the manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
5120169	27878568	MJT	2	assisted partly with the experiments	assisted partly with the experiments	Performed the experiments	Investigation	YES
5120169	27878568	MZ	2	conducted the experiments and wrote the manuscript	conducted the experiments and wrote the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5120169	27878568	PB	2	supervised the experiments partly and revised the manuscript	supervised the experiments partly and revised the manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
1920550	17653272	AJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1920550	17653272	AJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1920550	17653272	AJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1920550	17653272	AJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1920550	17653272	AJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1920550	17653272	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1920550	17653272	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1920550	17653272	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1920550	17653272	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1920550	17653272	CS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1920550	17653272	FH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1920550	17653272	GA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1920550	17653272	GA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1920550	17653272	GA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1920550	17653272	GA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1920550	17653272	GA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1920550	17653272	GC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1920550	17653272	GC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1920550	17653272	GC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1920550	17653272	GC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1920550	17653272	GF	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1920550	17653272	GF	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1920550	17653272	GF	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1920550	17653272	IF	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1920550	17653272	IF	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1920550	17653272	IN	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1920550	17653272	IN	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1920550	17653272	MA	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1920550	17653272	PD	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1920550	17653272	SH	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1920550	17653272	SH	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1920550	17653272	SS	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1920550	17653272	SS	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1920550	17653272	VB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1920550	17653272	VB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1920550	17653272	VB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1920550	17653272	VV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1920550	17653272	VV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1920550	17653272	VV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1920550	17653272	VV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1920550	17653272	VV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5742248	29312410	All authors	2	listed have made substantial, direct and intellectual contribution to the work, and approved it for publication	listed have made substantial, direct and intellectual contribution to the work, and approved it for publication	-	-	NO
5644144	29041914	All authors	2	reviewed and approved the final manuscript	reviewed and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5644144	29041914	BS	2	performed the dna and rna extractions	performed the dna and rna extractions	Performed the experiments	Investigation	YES
5644144	29041914	CW	2	performed the genome and transcriptome assembly and annotation	performed the genome and transcriptome assembly and annotation	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5644144	29041914	EJD	2	annotated and analysed the whole genome and transcriptome data for specific functions and wrote the corresponding text	annotated and analysed the whole genome and transcriptome data for specific functions and wrote the corresponding text	Analyzed the data|Wrote the paper	Data curation|Formal analysis|Writing - Original Draft	YES
5644144	29041914	KM	2	conducted the phylogenetic analysis	conducted the phylogenetic analysis	Performed the experiments	Investigation	YES
5644144	29041914	KR	2	annotated and analysed the whole genome and transcriptome data for specific functions and wrote the corresponding text	annotated and analysed the whole genome and transcriptome data for specific functions and wrote the corresponding text	Analyzed the data|Wrote the paper	Data curation|Formal analysis|Writing - Original Draft	YES
5644144	29041914	LT	2	performed the dna and rna extractions	performed the dna and rna extractions	Performed the experiments	Investigation	YES
5644144	29041914	MDJ	2	annotated and analysed the whole genome and transcriptome data for specific functions and wrote the corresponding text	annotated and analysed the whole genome and transcriptome data for specific functions and wrote the corresponding text	Analyzed the data|Wrote the paper	Data curation|Formal analysis|Writing - Original Draft	YES
5644144	29041914	MIS	2	conceived and designed the project and led the writing|performed the dna and rna extractions	conceived and designed the project and led the writing	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology	YES
5644144	29041914	MIS	2	conceived and designed the project and led the writing|performed the dna and rna extractions	performed the dna and rna extractions	Performed the experiments	Investigation	YES
5644144	29041914	NJG	2	conceived and designed the project and led the writing	conceived and designed the project and led the writing	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology	YES
5644144	29041914	PKD	2	annotated and analysed the whole genome and transcriptome data for specific functions and wrote the corresponding text	annotated and analysed the whole genome and transcriptome data for specific functions and wrote the corresponding text	Analyzed the data|Wrote the paper	Data curation|Formal analysis|Writing - Original Draft	YES
5644144	29041914	PPG	2	annotated and analysed the whole genome and transcriptome data for specific functions and wrote the corresponding text	annotated and analysed the whole genome and transcriptome data for specific functions and wrote the corresponding text	Analyzed the data|Wrote the paper	Data curation|Formal analysis|Writing - Original Draft	YES
5644144	29041914	RDN	2	conceived and designed the project and led the writing|annotated and analysed the whole genome and transcriptome data for specific functions and wrote the corresponding text	conceived and designed the project and led the writing	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology	YES
5644144	29041914	RDN	2	conceived and designed the project and led the writing|annotated and analysed the whole genome and transcriptome data for specific functions and wrote the corresponding text	annotated and analysed the whole genome and transcriptome data for specific functions and wrote the corresponding text	Analyzed the data|Wrote the paper	Data curation|Formal analysis|Writing - Original Draft	YES
5644144	29041914	RNC	2	annotated and analysed the whole genome and transcriptome data for specific functions and wrote the corresponding text	annotated and analysed the whole genome and transcriptome data for specific functions and wrote the corresponding text	Analyzed the data|Wrote the paper	Data curation|Formal analysis|Writing - Original Draft	YES
5644144	29041914	SB	2	conducted the phylogenetic analysis	conducted the phylogenetic analysis	Performed the experiments	Investigation	YES
5644144	29041914	SG	2	annotated and analysed the whole genome and transcriptome data for specific functions and wrote the corresponding text	annotated and analysed the whole genome and transcriptome data for specific functions and wrote the corresponding text	Analyzed the data|Wrote the paper	Data curation|Formal analysis|Writing - Original Draft	YES
5644144	29041914	TRB	2	conceived and designed the project and led the writing	conceived and designed the project and led the writing	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology	YES
4414601	25922940	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414601	25922940	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414601	25922940	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414601	25922940	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414601	25922940	SZ	PLoS5	Wrote the paper|Supervised the work	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414601	25922940	SZ	PLoS5	Wrote the paper|Supervised the work	Supervised the work	-	Supervision	YES
4414601	25922940	YS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Supervised the work	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414601	25922940	YS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Supervised the work	Analyzed the data	Analyzed the data	Formal analysis	YES
4414601	25922940	YS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Supervised the work	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414601	25922940	YS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Supervised the work	Supervised the work	-	Supervision	YES
6393253	30706242	AJ	2	contributed to the conception and design of the study and the analysis and interpretation of data, drafted the article or revised it critically for important intellectual content, and approved the final version to be published	contributed to the conception and design of the study and the analysis and interpretation of data, drafted the article or revised it critically for important intellectual content, and approved the final version to be published	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
6393253	30706242	AK	2	contributed to the conception and design of the study and the analysis and interpretation of data, drafted the article or revised it critically for important intellectual content, and approved the final version to be published	contributed to the conception and design of the study and the analysis and interpretation of data, drafted the article or revised it critically for important intellectual content, and approved the final version to be published	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
6393253	30706242	DF	2	contributed to the conception and design of the study and the analysis and interpretation of data, drafted the article or revised it critically for important intellectual content, and approved the final version to be published	contributed to the conception and design of the study and the analysis and interpretation of data, drafted the article or revised it critically for important intellectual content, and approved the final version to be published	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
6393253	30706242	EAT	2	contributed to the conception and design of the study and the analysis and interpretation of data, drafted the article or revised it critically for important intellectual content, and approved the final version to be published	contributed to the conception and design of the study and the analysis and interpretation of data, drafted the article or revised it critically for important intellectual content, and approved the final version to be published	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
6393253	30706242	IJS	2	contributed to the conception and design of the study and the analysis and interpretation of data, drafted the article or revised it critically for important intellectual content, and approved the final version to be published	contributed to the conception and design of the study and the analysis and interpretation of data, drafted the article or revised it critically for important intellectual content, and approved the final version to be published	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
6393253	30706242	PL	2	contributed to the conception and design of the study and the analysis and interpretation of data, drafted the article or revised it critically for important intellectual content, and approved the final version to be published	contributed to the conception and design of the study and the analysis and interpretation of data, drafted the article or revised it critically for important intellectual content, and approved the final version to be published	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
6393253	30706242	RHG	2	contributed to the conception and design of the study and the analysis and interpretation of data, drafted the article or revised it critically for important intellectual content, and approved the final version to be published	contributed to the conception and design of the study and the analysis and interpretation of data, drafted the article or revised it critically for important intellectual content, and approved the final version to be published	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
6393253	30706242	SS	2	contributed to the conception and design of the study and the analysis and interpretation of data, drafted the article or revised it critically for important intellectual content, and approved the final version to be published	contributed to the conception and design of the study and the analysis and interpretation of data, drafted the article or revised it critically for important intellectual content, and approved the final version to be published	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
1920551	17653273	TS	PLoS5	Wrote the paper|Derived the general equation for optimal decision boundaries|Found and analyzed specific solutions for several example probability distributions	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1920551	17653273	TS	PLoS5	Wrote the paper|Derived the general equation for optimal decision boundaries|Found and analyzed specific solutions for several example probability distributions	Derived the general equation for optimal decision boundaries	-	-	NO
1920551	17653273	TS	PLoS5	Wrote the paper|Derived the general equation for optimal decision boundaries|Found and analyzed specific solutions for several example probability distributions	Found and analyzed specific solutions for several example probability distributions	Analyzed the data	Formal analysis	YES
1920551	17653273	WB	PLoS5	Wrote the paper|Derived the general equation for optimal decision boundaries|Found and analyzed specific solutions for several example probability distributions	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1920551	17653273	WB	PLoS5	Wrote the paper|Derived the general equation for optimal decision boundaries|Found and analyzed specific solutions for several example probability distributions	Derived the general equation for optimal decision boundaries	-	-	NO
1920551	17653273	WB	PLoS5	Wrote the paper|Derived the general equation for optimal decision boundaries|Found and analyzed specific solutions for several example probability distributions	Found and analyzed specific solutions for several example probability distributions	Analyzed the data	Formal analysis	YES
5120623	27878786	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5120623	27878786	BL	2	provided a significant contribution to the design of the study, and also participated in the critical revision of each draft of the manuscript	provided a significant contribution to the design of the study, and also participated in the critical revision of each draft of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5120623	27878786	CN	2	conceived of the study initially and participated in its design, and also assisted in the drafting and revision of the manuscript	conceived of the study initially and participated in its design, and also assisted in the drafting and revision of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5120623	27878786	GPC	2	the gene expression analysis	the gene expression analysis	Performed the experiments	Investigation	YES
5120623	27878786	LJ	2	participated in the growth and harvest of bacterial cultures for the pha homopolymer experiments using various fatty acids, assisted in the preparation and analysis of samples for gc, performed the growth profile analysis, analyzed the polymer yields at 24 and 48 h, and drafted the figures and methods corresponding to the growth profile	participated in the growth and harvest of bacterial cultures for the pha homopolymer experiments using various fatty acids, assisted in the preparation and analysis of samples for gc, performed the growth profile analysis, analyzed the polymer yields at 24 and 48 h, and drafted the figures and methods corresponding to the growth profile	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Visualization|Writing - Original Draft	YES
5120623	27878786	RS	2	also drafted the manuscript in its entirety	also drafted the manuscript in its entirety	Wrote the paper	Writing - Original Draft	YES
5644170	29037165	DKL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5644170	29037165	FL	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5644170	29037165	JD	PLoS5	Conceived, designed and coordinated the work	Conceived, designed and coordinated the work	Conceived and designed the experiments	Conceptualization|Project administration	YES
5644170	29037165	JV	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5644170	29037165	MA	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5644170	29037165	MK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5644170	29037165	SHJ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5644170	29037165	WHY	PLoS5	Conceived, designed and coordinated the work	Conceived, designed and coordinated the work	Conceived and designed the experiments	Conceptualization|Project administration	YES
5644170	29037165	WWT	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
5644170	29037165	WWT	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5644170	29037165	WXE	PLoS5	Wrote the paper|Conceived, designed and coordinated the work	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5644170	29037165	WXE	PLoS5	Wrote the paper|Conceived, designed and coordinated the work	Conceived, designed and coordinated the work	Conceived and designed the experiments	Conceptualization|Project administration	YES
5644170	29037165	WYF	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5644170	29037165	XJ	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5644170	29037165	XJ	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5644170	29037165	YCY	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5644170	29037165	ZJ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4619761	26539468	Anil K. Rustgi	PLoS52	led the project and oversaw the analysis	led the project and oversaw the analysis	-	Supervision	YES
4619761	26539468	Blair B. Madison	PLoS52	designed and performed the experiments	designed and performed the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4619761	26539468	Qi Liu	PLoS52	conducted data analysis|wrote the paper	conducted data analysis	Analyzed the data	Formal analysis	YES
4619761	26539468	Qi Liu	PLoS52	conducted data analysis|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4619761	26539468	Xue Zhong	PLoS52	conducted data analysis	conducted data analysis	Analyzed the data	Formal analysis	YES
4619761	26539468	Yu Shyr	PLoS52	led the project and oversaw the analysis	led the project and oversaw the analysis	-	Supervision	YES
4414602	25923205	JDN	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4414602	25923205	JFC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4414602	25923205	JG	PLoS5	Critical review of the manuscript|Provided convenience for performing the experiments	Critical review of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4414602	25923205	JG	PLoS5	Critical review of the manuscript|Provided convenience for performing the experiments	Provided convenience for performing the experiments	Performed the experiments	Investigation	YES
4414602	25923205	JS	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4414602	25923205	MCL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414602	25923205	MCL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414602	25923205	MCL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414602	25923205	MCL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414602	25923205	MMX	PLoS5	Contributed reagents/materials/analysis tools|Critical review of the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414602	25923205	MMX	PLoS5	Contributed reagents/materials/analysis tools|Critical review of the manuscript	Critical review of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5742254	29312366	MKP	7	performed most of the experiments|interpreted the results|improved the manuscript|conceived, designed, and supervised the study and finalized the manuscript	performed most of the experiments	Performed the experiments	Investigation	YES
5742254	29312366	MKP	7	performed most of the experiments|interpreted the results|improved the manuscript|conceived, designed, and supervised the study and finalized the manuscript	interpreted the results	Analyzed the data	Formal analysis	YES
5742254	29312366	MKP	7	performed most of the experiments|interpreted the results|improved the manuscript|conceived, designed, and supervised the study and finalized the manuscript	improved the manuscript	Wrote the paper	Writing - Review & Editing	YES
5742254	29312366	MKP	7	performed most of the experiments|interpreted the results|improved the manuscript|conceived, designed, and supervised the study and finalized the manuscript	conceived, designed, and supervised the study and finalized the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Supervision|Writing - Review & Editing	YES
5742254	29312366	MKV	7	performed most of the experiments|analyzed genotyping data and conducted genetic analysis|interpreted the results|drafted the MS	performed most of the experiments	Performed the experiments	Investigation	YES
5742254	29312366	MKV	7	performed most of the experiments|analyzed genotyping data and conducted genetic analysis|interpreted the results|drafted the MS	analyzed genotyping data and conducted genetic analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5742254	29312366	MKV	7	performed most of the experiments|analyzed genotyping data and conducted genetic analysis|interpreted the results|drafted the MS	interpreted the results	Analyzed the data	Formal analysis	YES
5742254	29312366	MKV	7	performed most of the experiments|analyzed genotyping data and conducted genetic analysis|interpreted the results|drafted the MS	drafted the MS	Wrote the paper	Writing - Original Draft	YES
5742254	29312366	MS	7	generated genotyping data on diverse germplasm panel|analyzed genotyping data and conducted genetic analysis	generated genotyping data on diverse germplasm panel	Performed the experiments	Investigation	YES
5742254	29312366	MS	7	generated genotyping data on diverse germplasm panel|analyzed genotyping data and conducted genetic analysis	analyzed genotyping data and conducted genetic analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5742254	29312366	RKV	7	improved the manuscript|conceived, designed, and supervised the study and finalized the manuscript	improved the manuscript	Wrote the paper	Writing - Review & Editing	YES
5742254	29312366	RKV	7	improved the manuscript|conceived, designed, and supervised the study and finalized the manuscript	conceived, designed, and supervised the study and finalized the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Supervision|Writing - Review & Editing	YES
5742254	29312366	SMK	7	performed indel marker discovery and primer designing	performed indel marker discovery and primer designing	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5742254	29312366	TN	7	generated genotyping data on diverse germplasm panel	generated genotyping data on diverse germplasm panel	Performed the experiments	Investigation	YES
5742254	29312366	VG	7	analyzed genotyping data and conducted genetic analysis	analyzed genotyping data and conducted genetic analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5742254	29312366	YS	7	generated genotyping data on diverse germplasm panel	generated genotyping data on diverse germplasm panel	Performed the experiments	Investigation	YES
1920552	17653269	JA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1920552	17653269	JA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1920552	17653269	JA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1920552	17653269	JL	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1920552	17653269	JL	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1920552	17653269	SK	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1920552	17653269	SK	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1920552	17653269	SY	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1920552	17653269	SY	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1920552	17653269	SY	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1920552	17653269	YK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4414603	25923465	AM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414603	25923465	AM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414603	25923465	AM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414603	25923465	AM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414603	25923465	GKC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4414603	25923465	LVR	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414603	25923465	LVR	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414603	25923465	LVR	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414603	25923465	MCL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4414603	25923465	VAVNB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414603	25923465	VAVNB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414603	25923465	VAVNB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414603	25923465	VAVNB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5125315	27896786	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5125315	27896786	CW	2	analyzed data and wrote the paper	analyzed data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5125315	27896786	FL	2	performed research	performed research	Performed the experiments	Investigation	YES
5125315	27896786	LH	2	designed research|analyzed data and wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
5125315	27896786	LH	2	designed research|analyzed data and wrote the paper	analyzed data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5125315	27896786	WM	2	performed research	performed research	Performed the experiments	Investigation	YES
5125315	27896786	ZX	2	designed research|performed research|analyzed data and wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
5125315	27896786	ZX	2	designed research|performed research|analyzed data and wrote the paper	performed research	Performed the experiments	Investigation	YES
5125315	27896786	ZX	2	designed research|performed research|analyzed data and wrote the paper	analyzed data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4636865	26547082	Claudia A. Steiner	2	coordinated review of the nationwide inpatient sample data, reviewed and approved the manuscript as submitted	coordinated review of the nationwide inpatient sample data, reviewed and approved the manuscript as submitted	Wrote the paper	Project administration|Writing - Review & Editing	YES
4636865	26547082	Eric M. Foote	2	conceptualized and designed the study, drafted the manuscript and approved the manuscript as submitted	conceptualized and designed the study, drafted the manuscript and approved the manuscript as submitted	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
4636865	26547082	Michael Bartholomew	2	assisted in conceptualizing and designing the study, reviewed and revised the initial manuscript and approved the final manuscript as submitted	assisted in conceptualizing and designing the study, reviewed and revised the initial manuscript and approved the final manuscript as submitted	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
4636865	26547082	Robert C. Holman	2	carried out the data analyses, coordinated the use of the data, revised manuscript drafts and approved the final manuscript as submitted	carried out the data analyses, coordinated the use of the data, revised manuscript drafts and approved the final manuscript as submitted	Analyzed the data|Wrote the paper	Formal analysis|Project administration|Writing - Original Draft|Writing - Review & Editing	YES
4636865	26547082	Rosalyn J. Singleton	2	conceptualized and designed the study, drafted the manuscript and approved the manuscript as submitted	conceptualized and designed the study, drafted the manuscript and approved the manuscript as submitted	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
4636865	26547082	Sara M. Seeman	2	carried out the data analyses, coordinated the use of the data, revised manuscript drafts and approved the final manuscript as submitted	carried out the data analyses, coordinated the use of the data, revised manuscript drafts and approved the final manuscript as submitted	Analyzed the data|Wrote the paper	Formal analysis|Project administration|Writing - Original Draft|Writing - Review & Editing	YES
4636865	26547082	Thomas W. Hennessy	2	assisted in conceptualizing and designing the study, reviewed and revised the initial manuscript and approved the final manuscript as submitted	assisted in conceptualizing and designing the study, reviewed and revised the initial manuscript and approved the final manuscript as submitted	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
5742256	29312379	AA	7	analyzed the data with the input from L-SPT	analyzed the data with the input from L-SPT	Analyzed the data	Formal analysis	YES
5742256	29312379	AH	7	analyzed the data with the input from L-SPT|wrote the paper	analyzed the data with the input from L-SPT	Analyzed the data	Formal analysis	YES
5742256	29312379	AH	7	analyzed the data with the input from L-SPT|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5742256	29312379	EA	7	analyzed the data with the input from L-SPT|contributed reagents, materials, analysis tools|wrote the paper	analyzed the data with the input from L-SPT	Analyzed the data	Formal analysis	YES
5742256	29312379	EA	7	analyzed the data with the input from L-SPT|contributed reagents, materials, analysis tools|wrote the paper	contributed reagents, materials, analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5742256	29312379	EA	7	analyzed the data with the input from L-SPT|contributed reagents, materials, analysis tools|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5742256	29312379	FB	7	analyzed the data with the input from L-SPT|wrote the paper	analyzed the data with the input from L-SPT	Analyzed the data	Formal analysis	YES
5742256	29312379	FB	7	analyzed the data with the input from L-SPT|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5742256	29312379	L-SPT	7	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5742256	29312379	MJ	7	conceived and designed the experiments|performed the experiments|analyzed the data with the input from L-SPT|contributed reagents, materials, analysis tools|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5742256	29312379	MJ	7	conceived and designed the experiments|performed the experiments|analyzed the data with the input from L-SPT|contributed reagents, materials, analysis tools|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5742256	29312379	MJ	7	conceived and designed the experiments|performed the experiments|analyzed the data with the input from L-SPT|contributed reagents, materials, analysis tools|wrote the paper	analyzed the data with the input from L-SPT	Analyzed the data	Formal analysis	YES
5742256	29312379	MJ	7	conceived and designed the experiments|performed the experiments|analyzed the data with the input from L-SPT|contributed reagents, materials, analysis tools|wrote the paper	contributed reagents, materials, analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5742256	29312379	MJ	7	conceived and designed the experiments|performed the experiments|analyzed the data with the input from L-SPT|contributed reagents, materials, analysis tools|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5742256	29312379	OO	7	conceived and designed the experiments|performed the experiments|analyzed the data with the input from L-SPT|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5742256	29312379	OO	7	conceived and designed the experiments|performed the experiments|analyzed the data with the input from L-SPT|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5742256	29312379	OO	7	conceived and designed the experiments|performed the experiments|analyzed the data with the input from L-SPT|wrote the paper	analyzed the data with the input from L-SPT	Analyzed the data	Formal analysis	YES
5742256	29312379	OO	7	conceived and designed the experiments|performed the experiments|analyzed the data with the input from L-SPT|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5742256	29312379	SS	7	analyzed the data with the input from L-SPT|wrote the paper	analyzed the data with the input from L-SPT	Analyzed the data	Formal analysis	YES
5742256	29312379	SS	7	analyzed the data with the input from L-SPT|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5644175	29037153	AM	2	designed the study|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5644175	29037153	AM	2	designed the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5644175	29037153	NO	2	designed the study|performed experiments and bioinformatics analysis|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5644175	29037153	NO	2	designed the study|performed experiments and bioinformatics analysis|wrote the manuscript	performed experiments and bioinformatics analysis	Performed the experiments	Formal analysis|Investigation	YES
5644175	29037153	NO	2	designed the study|performed experiments and bioinformatics analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
1920553	17653281	BC	PLoS5	Contributed to the data analysis	Contributed to the data analysis	Analyzed the data	Formal analysis	YES
1920553	17653281	BS	PLoS5	Designed the study	Designed the study	Conceived and designed the experiments	Methodology	YES
1920553	17653281	FT	PLoS5	Contributed to the design of the study and contributed to the data interpretation	Contributed to the design of the study and contributed to the data interpretation	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Methodology|Resources	YES
1920553	17653281	NV	PLoS5	Designed the study|Performed the data collection and analysis|Wrote the paper	Designed the study	Conceived and designed the experiments	Methodology	YES
1920553	17653281	NV	PLoS5	Designed the study|Performed the data collection and analysis|Wrote the paper	Performed the data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
1920553	17653281	NV	PLoS5	Designed the study|Performed the data collection and analysis|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1920553	17653281	TC	PLoS5	Designed the study	Designed the study	Conceived and designed the experiments	Methodology	YES
4414604	25923209	AKT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414604	25923209	AKT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414604	25923209	AKT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414604	25923209	AKT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414604	25923209	DS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414604	25923209	DS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414604	25923209	JC	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414604	25923209	JS	PLoS5	Performed the experiments|Contributed to conception and design, acquisition of data	Performed the experiments	Performed the experiments	Investigation	YES
4414604	25923209	JS	PLoS5	Performed the experiments|Contributed to conception and design, acquisition of data	Contributed to conception and design, acquisition of data	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceptualization|Investigation|Resources	YES
4414604	25923209	KD	PLoS5	Performed the experiments|Contributed to conception and design, acquisition of data	Performed the experiments	Performed the experiments	Investigation	YES
4414604	25923209	KD	PLoS5	Performed the experiments|Contributed to conception and design, acquisition of data	Contributed to conception and design, acquisition of data	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceptualization|Investigation|Resources	YES
4414604	25923209	MK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4414604	25923209	RK	PLoS5	Contributed to conception and design, acquisition of data	Contributed to conception and design, acquisition of data	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceptualization|Investigation|Resources	YES
4414604	25923209	SL	PLoS5	Contributed to conception and design, acquisition of data	Contributed to conception and design, acquisition of data	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceptualization|Investigation|Resources	YES
4414604	25923209	SR	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414604	25923209	SR	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5128008	27900727	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5128008	27900727	HW	2	participated in the design of the study, and supervised the research work|helped to review and editing the manuscript|participated in the providing the necessary resources and funding acquisition	participated in the design of the study, and supervised the research work	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Supervision	YES
5128008	27900727	HW	2	participated in the design of the study, and supervised the research work|helped to review and editing the manuscript|participated in the providing the necessary resources and funding acquisition	helped to review and editing the manuscript	Wrote the paper	Writing - Review & Editing	YES
5128008	27900727	HW	2	participated in the design of the study, and supervised the research work|helped to review and editing the manuscript|participated in the providing the necessary resources and funding acquisition	participated in the providing the necessary resources and funding acquisition	Contributed reagents/materials/analysis tools	Funding acquisition|Resources	YES
5128008	27900727	JP	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5128008	27900727	JW	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5128008	27900727	KW	2	participated in the design of the study, and supervised the research work|drafted the original manuscript|participated in the providing the necessary resources and funding acquisition	participated in the design of the study, and supervised the research work	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Supervision	YES
5128008	27900727	KW	2	participated in the design of the study, and supervised the research work|drafted the original manuscript|participated in the providing the necessary resources and funding acquisition	drafted the original manuscript	Wrote the paper	Writing - Original Draft	YES
5128008	27900727	KW	2	participated in the design of the study, and supervised the research work|drafted the original manuscript|participated in the providing the necessary resources and funding acquisition	participated in the providing the necessary resources and funding acquisition	Contributed reagents/materials/analysis tools	Funding acquisition|Resources	YES
5128008	27900727	MZ	2	carried out the experiments|helped to review and editing the manuscript|participated in the providing the necessary resources and funding acquisition	carried out the experiments	Performed the experiments	Investigation	YES
5128008	27900727	MZ	2	carried out the experiments|helped to review and editing the manuscript|participated in the providing the necessary resources and funding acquisition	helped to review and editing the manuscript	Wrote the paper	Writing - Review & Editing	YES
5128008	27900727	MZ	2	carried out the experiments|helped to review and editing the manuscript|participated in the providing the necessary resources and funding acquisition	participated in the providing the necessary resources and funding acquisition	Contributed reagents/materials/analysis tools	Funding acquisition|Resources	YES
5128008	27900727	PZ	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5128008	27900727	RW	2	participated in the design of the study, and supervised the research work|helped to review and editing the manuscript|take part in the project administration and funding acquisition|participated in the providing the necessary resources and funding acquisition	participated in the design of the study, and supervised the research work	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Supervision	YES
5128008	27900727	RW	2	participated in the design of the study, and supervised the research work|helped to review and editing the manuscript|take part in the project administration and funding acquisition|participated in the providing the necessary resources and funding acquisition	helped to review and editing the manuscript	Wrote the paper	Writing - Review & Editing	YES
5128008	27900727	RW	2	participated in the design of the study, and supervised the research work|helped to review and editing the manuscript|take part in the project administration and funding acquisition|participated in the providing the necessary resources and funding acquisition	take part in the project administration and funding acquisition	-	Funding acquisition|Project administration	YES
5128008	27900727	RW	2	participated in the design of the study, and supervised the research work|helped to review and editing the manuscript|take part in the project administration and funding acquisition|participated in the providing the necessary resources and funding acquisition	participated in the providing the necessary resources and funding acquisition	Contributed reagents/materials/analysis tools	Funding acquisition|Resources	YES
5128008	27900727	RZ	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5128008	27900727	SQ	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5128008	27900727	WY	2	participated in the design of the study, and supervised the research work|helped to review and editing the manuscript|take part in the project administration and funding acquisition|participated in the providing the necessary resources and funding acquisition	participated in the design of the study, and supervised the research work	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Supervision	YES
5128008	27900727	WY	2	participated in the design of the study, and supervised the research work|helped to review and editing the manuscript|take part in the project administration and funding acquisition|participated in the providing the necessary resources and funding acquisition	helped to review and editing the manuscript	Wrote the paper	Writing - Review & Editing	YES
5128008	27900727	WY	2	participated in the design of the study, and supervised the research work|helped to review and editing the manuscript|take part in the project administration and funding acquisition|participated in the providing the necessary resources and funding acquisition	take part in the project administration and funding acquisition	-	Funding acquisition|Project administration	YES
5128008	27900727	WY	2	participated in the design of the study, and supervised the research work|helped to review and editing the manuscript|take part in the project administration and funding acquisition|participated in the providing the necessary resources and funding acquisition	participated in the providing the necessary resources and funding acquisition	Contributed reagents/materials/analysis tools	Funding acquisition|Resources	YES
5128008	27900727	YL	2	participated in the design of the study, and supervised the research work|helped to review and editing the manuscript|participated in the providing the necessary resources and funding acquisition	participated in the design of the study, and supervised the research work	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Supervision	YES
5128008	27900727	YL	2	participated in the design of the study, and supervised the research work|helped to review and editing the manuscript|participated in the providing the necessary resources and funding acquisition	helped to review and editing the manuscript	Wrote the paper	Writing - Review & Editing	YES
5128008	27900727	YL	2	participated in the design of the study, and supervised the research work|helped to review and editing the manuscript|participated in the providing the necessary resources and funding acquisition	participated in the providing the necessary resources and funding acquisition	Contributed reagents/materials/analysis tools	Funding acquisition|Resources	YES
5128008	27900727	YZ	2	carried out the experiments|drafted the original manuscript	carried out the experiments	Performed the experiments	Investigation	YES
5128008	27900727	YZ	2	carried out the experiments|drafted the original manuscript	drafted the original manuscript	Wrote the paper	Writing - Original Draft	YES
5644186	29037167	CIA	2	conceived and designed study|reviewed and edited the manuscript	conceived and designed study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5644186	29037167	CIA	2	conceived and designed study|reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5644186	29037167	IPG	2	reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5644186	29037167	JAB	2	reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5644186	29037167	JY	2	conceived and designed study|developed methods|performed the computational analyses|reviewed and edited the manuscript	conceived and designed study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5644186	29037167	JY	2	conceived and designed study|developed methods|performed the computational analyses|reviewed and edited the manuscript	developed methods	Performed the experiments	Methodology	YES
5644186	29037167	JY	2	conceived and designed study|developed methods|performed the computational analyses|reviewed and edited the manuscript	performed the computational analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5644186	29037167	JY	2	conceived and designed study|developed methods|performed the computational analyses|reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5644186	29037167	MFS	2	reviewed and edited the manuscript|provided the curated genetic ancestry data	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5644186	29037167	MFS	2	reviewed and edited the manuscript|provided the curated genetic ancestry data	provided the curated genetic ancestry data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Investigation|Resources	YES
5644186	29037167	YH	2	conceived and designed study|developed methods|reviewed and edited the manuscript	conceived and designed study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5644186	29037167	YH	2	conceived and designed study|developed methods|reviewed and edited the manuscript	developed methods	Performed the experiments	Methodology	YES
5644186	29037167	YH	2	conceived and designed study|developed methods|reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
1920554	17668046	AI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1920554	17668046	AI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1920554	17668046	AI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1920554	17668046	AI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1920554	17668046	AN	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1920554	17668046	AN	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1920554	17668046	AN	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1920554	17668046	BB	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1920554	17668046	BB	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1920554	17668046	CP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1920554	17668046	CP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1920554	17668046	CP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1920554	17668046	MB	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1920554	17668046	MB	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1920554	17668046	RA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1920554	17668046	RA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1920554	17668046	RA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5742262	29312392	ES	2	revised and finalized the manuscript	revised and finalized the manuscript	Wrote the paper	Writing - Review & Editing	YES
5742262	29312392	TK	2	revised and finalized the manuscript	revised and finalized the manuscript	Wrote the paper	Writing - Review & Editing	YES
5742262	29312392	YD	2	revised and finalized the manuscript	revised and finalized the manuscript	Wrote the paper	Writing - Review & Editing	YES
5742262	29312392	all the authors	2	read and approved the manuscript	read and approved the manuscript	-	-	NO
5138170	27921270	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5138170	27921270	GG	2	performed experiments, and analyzed data	performed experiments, and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5138170	27921270	JHL	2	performed experiments, and analyzed data|designed experiments and wrote the manuscript	performed experiments, and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5138170	27921270	JHL	2	performed experiments, and analyzed data|designed experiments and wrote the manuscript	designed experiments and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5138170	27921270	JL	2	conceived of the study|designed experiments and wrote the manuscript	conceived of the study	Conceived and designed the experiments	Conceptualization	YES
5138170	27921270	JL	2	conceived of the study|designed experiments and wrote the manuscript	designed experiments and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5138170	27921270	TKW	2	conceived of the study	conceived of the study	Conceived and designed the experiments	Conceptualization	YES
5138170	27921270	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5138170	27921270	YGK	2	performed experiments, and analyzed data	performed experiments, and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4414605	25923767	AR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Developed, implemented, and improved the software tool	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414605	25923767	AR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Developed, implemented, and improved the software tool	Performed the experiments	Performed the experiments	Investigation	YES
4414605	25923767	AR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Developed, implemented, and improved the software tool	Analyzed the data	Analyzed the data	Formal analysis	YES
4414605	25923767	AR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Developed, implemented, and improved the software tool	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414605	25923767	AR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Developed, implemented, and improved the software tool	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414605	25923767	AR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Developed, implemented, and improved the software tool	Developed, implemented, and improved the software tool	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
4414605	25923767	BV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Developed, implemented, and improved the software tool|Modified the tool, performed the new experiments for revised version, and addressed the reviewers comments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414605	25923767	BV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Developed, implemented, and improved the software tool|Modified the tool, performed the new experiments for revised version, and addressed the reviewers comments	Performed the experiments	Performed the experiments	Investigation	YES
4414605	25923767	BV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Developed, implemented, and improved the software tool|Modified the tool, performed the new experiments for revised version, and addressed the reviewers comments	Analyzed the data	Analyzed the data	Formal analysis	YES
4414605	25923767	BV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Developed, implemented, and improved the software tool|Modified the tool, performed the new experiments for revised version, and addressed the reviewers comments	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414605	25923767	BV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Developed, implemented, and improved the software tool|Modified the tool, performed the new experiments for revised version, and addressed the reviewers comments	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414605	25923767	BV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Developed, implemented, and improved the software tool|Modified the tool, performed the new experiments for revised version, and addressed the reviewers comments	Developed, implemented, and improved the software tool	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
4414605	25923767	BV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Developed, implemented, and improved the software tool|Modified the tool, performed the new experiments for revised version, and addressed the reviewers comments	Modified the tool, performed the new experiments for revised version, and addressed the reviewers comments	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4414605	25923767	CB	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper|Developed, implemented, and improved the software tool	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414605	25923767	CB	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper|Developed, implemented, and improved the software tool	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414605	25923767	CB	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper|Developed, implemented, and improved the software tool	Developed, implemented, and improved the software tool	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
4414605	25923767	HM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the parallel and distributed algorithm|Developed, implemented, and improved the software tool|Modified the tool, performed the new experiments for revised version, and addressed the reviewers comments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414605	25923767	HM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the parallel and distributed algorithm|Developed, implemented, and improved the software tool|Modified the tool, performed the new experiments for revised version, and addressed the reviewers comments	Performed the experiments	Performed the experiments	Investigation	YES
4414605	25923767	HM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the parallel and distributed algorithm|Developed, implemented, and improved the software tool|Modified the tool, performed the new experiments for revised version, and addressed the reviewers comments	Analyzed the data	Analyzed the data	Formal analysis	YES
4414605	25923767	HM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the parallel and distributed algorithm|Developed, implemented, and improved the software tool|Modified the tool, performed the new experiments for revised version, and addressed the reviewers comments	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414605	25923767	HM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the parallel and distributed algorithm|Developed, implemented, and improved the software tool|Modified the tool, performed the new experiments for revised version, and addressed the reviewers comments	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414605	25923767	HM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the parallel and distributed algorithm|Developed, implemented, and improved the software tool|Modified the tool, performed the new experiments for revised version, and addressed the reviewers comments	Designed the parallel and distributed algorithm	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
4414605	25923767	HM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the parallel and distributed algorithm|Developed, implemented, and improved the software tool|Modified the tool, performed the new experiments for revised version, and addressed the reviewers comments	Developed, implemented, and improved the software tool	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
4414605	25923767	HM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the parallel and distributed algorithm|Developed, implemented, and improved the software tool|Modified the tool, performed the new experiments for revised version, and addressed the reviewers comments	Modified the tool, performed the new experiments for revised version, and addressed the reviewers comments	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4414605	25923767	IB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the parallel and distributed algorithm|Modified the tool, performed the new experiments for revised version, and addressed the reviewers comments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414605	25923767	IB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the parallel and distributed algorithm|Modified the tool, performed the new experiments for revised version, and addressed the reviewers comments	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414605	25923767	IB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the parallel and distributed algorithm|Modified the tool, performed the new experiments for revised version, and addressed the reviewers comments	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414605	25923767	IB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the parallel and distributed algorithm|Modified the tool, performed the new experiments for revised version, and addressed the reviewers comments	Designed the parallel and distributed algorithm	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
4414605	25923767	IB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the parallel and distributed algorithm|Modified the tool, performed the new experiments for revised version, and addressed the reviewers comments	Modified the tool, performed the new experiments for revised version, and addressed the reviewers comments	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4414605	25923767	JC	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper|Developed, implemented, and improved the software tool	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414605	25923767	JC	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper|Developed, implemented, and improved the software tool	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414605	25923767	JC	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper|Developed, implemented, and improved the software tool	Developed, implemented, and improved the software tool	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
4414605	25923767	SJ	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414605	25923767	SJ	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5645894	29041902	HJ	2	took part in data interpretation and manuscript writing and editing	took part in data interpretation and manuscript writing and editing	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5645894	29041902	XC	2	took part in data analysis and interpretation, and manuscript writing and editing	took part in data analysis and interpretation, and manuscript writing and editing	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
1920555	17653275	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1920555	17653275	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1920555	17653275	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1920555	17653275	AK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1920555	17653275	AW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1920555	17653275	AW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1920555	17653275	AW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1920555	17653275	CM	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1920555	17653275	CM	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1920555	17653275	CQ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1920555	17653275	CQ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1920555	17653275	CQ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1920555	17653275	CQ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1920555	17653275	EW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1920555	17653275	EW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1920555	17653275	EW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1920555	17653275	KS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1920555	17653275	SK	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1920555	17653275	SL	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1920555	17653275	TS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1920555	17653275	TS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1920555	17653275	TS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1920555	17653275	TS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5153395	27957724	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5153395	27957724	JB	2	planned and executed the experiments, collected and calculated all data, created the graphs and figures and drafted this manuscript	planned and executed the experiments, collected and calculated all data, created the graphs and figures and drafted this manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Visualization|Writing - Original Draft	YES
5153395	27957724	MH	2	significantly contributed to data evaluation and interpretation of the experiment as well as graphs and figures	significantly contributed to data evaluation and interpretation of the experiment as well as graphs and figures	Analyzed the data	Formal analysis|Visualization	YES
5153395	27957724	RH	2	substantially contributed to conception and design of the conducted experiments and contributed in manuscript writing	substantially contributed to conception and design of the conducted experiments and contributed in manuscript writing	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Writing - Original Draft	YES
5153395	27957724	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5646149	29041903	JLB	2	designed the study and was a major contributor in writing the manuscript|read, corrected and approved the final manuscript	designed the study and was a major contributor in writing the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5646149	29041903	JLB	2	designed the study and was a major contributor in writing the manuscript|read, corrected and approved the final manuscript	read, corrected and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5646149	29041903	MK	2	programmed and conducted all described calculations and drafted the manuscript	programmed and conducted all described calculations and drafted the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Software|Writing - Original Draft	YES
4414606	25923739	EA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414606	25923739	EA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414606	25923739	EA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414606	25923739	EA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414606	25923739	HCO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414606	25923739	HCO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4414606	25923739	HCO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4414606	25923739	HCO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5742265	29312394	AH	7	participated in the surveys	participated in the surveys	Performed the experiments	Investigation	YES
5742265	29312394	BH	7	conceived and designed the experiments and revised the manuscript	conceived and designed the experiments and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
5742265	29312394	BP	7	participated in the surveys	participated in the surveys	Performed the experiments	Investigation	YES
5742265	29312394	FG	7	conceived and designed the experiments and revised the manuscript	conceived and designed the experiments and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
5742265	29312394	GC	7	conceived and designed the experiments and revised the manuscript	conceived and designed the experiments and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
5742265	29312394	J-JC	7	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5742265	29312394	JaF	7	participated in the surveys	participated in the surveys	Performed the experiments	Investigation	YES
5742265	29312394	JeF	7	participated in the surveys	participated in the surveys	Performed the experiments	Investigation	YES
5742265	29312394	NY	7	conceived and designed the experiments, performed the experiments, analyzed the data, wrote the paper, and prepared the figures and tables	conceived and designed the experiments, performed the experiments, analyzed the data, wrote the paper, and prepared the figures and tables	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Visualization|Writing - Original Draft	YES
5742265	29312394	PP	7	conceived and designed the experiments and revised the manuscript	conceived and designed the experiments and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
5742265	29312394	RJ	7	participated in the surveys	participated in the surveys	Performed the experiments	Investigation	YES
5742265	29312394	SP	7	conceived and designed the experiments and revised the manuscript	conceived and designed the experiments and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
5742265	29312394	SR	7	provided the unpublished madagascar strains	provided the unpublished madagascar strains	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5742265	29312394	YJ-F	7	participated in the surveys	participated in the surveys	Performed the experiments	Investigation	YES
5174012	28000139	AK	2	designed and guided the study	designed and guided the study	Conceived and designed the experiments	Methodology|Supervision	YES
5174012	28000139	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5174012	28000139	DS	2	conceived the idea for this research and designed the experiments|performed the metabolomic analyses|wrote the manuscript	conceived the idea for this research and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5174012	28000139	DS	2	conceived the idea for this research and designed the experiments|performed the metabolomic analyses|wrote the manuscript	performed the metabolomic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5174012	28000139	DS	2	conceived the idea for this research and designed the experiments|performed the metabolomic analyses|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5174012	28000139	KS	2	conceived the idea for this research and designed the experiments|wrote the manuscript	conceived the idea for this research and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5174012	28000139	KS	2	conceived the idea for this research and designed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5174012	28000139	YT	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
1920556	17653276	AH	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1920556	17653276	AH	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1920556	17653276	AR	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1920556	17653276	AU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1920556	17653276	AU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1920556	17653276	AU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1920556	17653276	CD	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1920556	17653276	CD	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1920556	17653276	GP	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1920556	17653276	GP	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1920556	17653276	HD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Wrote the first draft of the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1920556	17653276	HD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Wrote the first draft of the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1920556	17653276	HD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Wrote the first draft of the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1920556	17653276	HD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Wrote the first draft of the paper	Wrote the first draft of the paper	Wrote the paper	Writing - Original Draft	YES
1920556	17653276	HN	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1920556	17653276	HN	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1920556	17653276	JW	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1920556	17653276	KP	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1920556	17653276	KP	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1920556	17653276	MD	PLoS5	Conceived and designed the study|Enrolled patients	Conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
1920556	17653276	MD	PLoS5	Conceived and designed the study|Enrolled patients	Enrolled patients	Performed the experiments	Investigation	YES
1920556	17653276	MH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1920556	17653276	MJ	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1920556	17653276	MJ	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1920556	17653276	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1920556	17653276	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1920556	17653276	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1920556	17653276	MO	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1920556	17653276	MO	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1920556	17653276	NG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1920556	17653276	NG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1920556	17653276	NS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1920556	17653276	NS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1920556	17653276	PK	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1920556	17653276	PK	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1920556	17653276	PK	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1920556	17653276	RP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1920556	17653276	RP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1920556	17653276	RT	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1920556	17653276	RT	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1920556	17653276	RZ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1920556	17653276	SF	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1920556	17653276	SG	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1920556	17653276	SG	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1920556	17653276	TB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1920556	17653276	TB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1920556	17653276	TG	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1920556	17653276	TS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1920556	17653276	TS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1920556	17653276	TS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1920556	17653276	WS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1920556	17653276	WS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5646159	29041922	HC	2	collected data	collected data	Performed the experiments	Investigation	YES
5646159	29041922	JL	2	conceived and supervised this work|constructed the database and tools|collected data|modified the manuscript	conceived and supervised this work	Conceived and designed the experiments	Conceptualization|Supervision	YES
5646159	29041922	JL	2	conceived and supervised this work|constructed the database and tools|collected data|modified the manuscript	constructed the database and tools	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5646159	29041922	JL	2	conceived and supervised this work|constructed the database and tools|collected data|modified the manuscript	collected data	Performed the experiments	Investigation	YES
5646159	29041922	JL	2	conceived and supervised this work|constructed the database and tools|collected data|modified the manuscript	modified the manuscript	Wrote the paper	Writing - Review & Editing	YES
5646159	29041922	JZ	2	constructed the database and tools|collected data|mainly curated the data|drafted manuscript	constructed the database and tools	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5646159	29041922	JZ	2	constructed the database and tools|collected data|mainly curated the data|drafted manuscript	collected data	Performed the experiments	Investigation	YES
5646159	29041922	JZ	2	constructed the database and tools|collected data|mainly curated the data|drafted manuscript	mainly curated the data	Analyzed the data	Data curation	YES
5646159	29041922	JZ	2	constructed the database and tools|collected data|mainly curated the data|drafted manuscript	drafted manuscript	Wrote the paper	Writing - Original Draft	YES
5646159	29041922	LX	2	collected data	collected data	Performed the experiments	Investigation	YES
5646159	29041922	LZ	2	collected data|modified the manuscript	collected data	Performed the experiments	Investigation	YES
5646159	29041922	LZ	2	collected data|modified the manuscript	modified the manuscript	Wrote the paper	Writing - Review & Editing	YES
5646159	29041922	RZ	2	constructed the database and tools	constructed the database and tools	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5646159	29041922	WX	2	conceived and supervised this work|modified the manuscript	conceived and supervised this work	Conceived and designed the experiments	Conceptualization|Supervision	YES
5646159	29041922	WX	2	conceived and supervised this work|modified the manuscript	modified the manuscript	Wrote the paper	Writing - Review & Editing	YES
5646159	29041922	XH	2	collected data|modified the manuscript	collected data	Performed the experiments	Investigation	YES
5646159	29041922	XH	2	collected data|modified the manuscript	modified the manuscript	Wrote the paper	Writing - Review & Editing	YES
5646159	29041922	XJ	2	collected data	collected data	Performed the experiments	Investigation	YES
5646159	29041922	ZS	2	collected data	collected data	Performed the experiments	Investigation	YES
6393260	30617944	BC	CRediT	Concept and design	Concept and design	Conceived and designed the experiments	Conceptualization	YES
6393260	30617944	CL	CRediT	Concept and design|supervision	Concept and design	Conceived and designed the experiments	Conceptualization	YES
6393260	30617944	CL	CRediT	Concept and design|supervision	supervision	-	Supervision	YES
6393260	30617944	HA	CRediT	supervision	supervision	-	Supervision	YES
4414607	25923438	HQ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414607	25923438	HQ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414607	25923438	HQ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414607	25923438	HS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4414607	25923438	HS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414607	25923438	LG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4414607	25923438	MJ	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4414607	25923438	MJ	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4414607	25923438	MP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414607	25923438	MP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414607	25923438	MP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414607	25923438	QW	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414607	25923438	QW	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414607	25923438	XL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414607	25923438	XL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414607	25923438	XL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414607	25923438	XL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414607	25923438	YH	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4414607	25923438	YH	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414607	25923438	YL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4414607	25923438	ZK	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414607	25923438	ZK	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414607	25923438	ZK	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1920557	17653278	DW	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1920557	17653278	HV	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1920557	17653278	MY	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1920557	17653278	PL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1920557	17653278	PL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1920557	17653278	PL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1920557	17653278	PL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1920557	17653278	YL	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5177599	28004362	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5177599	28004362	HEQEP	2	the university grants commission of bangladesh for supporting the establishment of laboratory facilities	the university grants commission of bangladesh for supporting the establishment of laboratory facilities	-	-	NO
5177599	28004362	MAH	2	developed hypothesis, supervised the whole work and helped prepare the manuscript	developed hypothesis, supervised the whole work and helped prepare the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Supervision|Writing - Original Draft	YES
5177599	28004362	MS	2	developed hypothesis, supervised the work on bench and helped prepare the manuscript	developed hypothesis, supervised the work on bench and helped prepare the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Supervision|Writing - Original Draft	YES
5177599	28004362	Mouth Disease Vaccine	2	biofilm formation, and heavy metal resistance in bacteria	biofilm formation, and heavy metal resistance in bacteria	-	-	NO
5177599	28004362	RPC	2	designed and worked on bench as well as drafted the manuscript	designed and worked on bench as well as drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Writing - Original Draft	YES
5177599	28004362	SA	2	partially carried out work on bench and helped prepare the manuscript	partially carried out work on bench and helped prepare the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5177599	28004362	SS	2	partially carried out work on bench and helped draft the manuscript	partially carried out work on bench and helped draft the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5177599	28004362	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5742266	29312403	FH	2	performed the experiments, analyzed the data and wrote the manuscript	performed the experiments, analyzed the data and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5742266	29312403	HW	2	designed the study and discussed the manuscript	designed the study and discussed the manuscript	Conceived and designed the experiments	Methodology	YES
5742266	29312403	MR	2	designed the study and discussed the manuscript	designed the study and discussed the manuscript	Conceived and designed the experiments	Methodology	YES
5742266	29312403	PX	2	performed the experiments, analyzed the data and wrote the manuscript	performed the experiments, analyzed the data and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5742266	29312403	SL	2	designed the study and discussed the manuscript	designed the study and discussed the manuscript	Conceived and designed the experiments	Methodology	YES
5742266	29312403	XL	2	designed the study and discussed the manuscript	designed the study and discussed the manuscript	Conceived and designed the experiments	Methodology	YES
5742266	29312403	YB	2	performed the experiments, analyzed the data and wrote the manuscript	performed the experiments, analyzed the data and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5742266	29312403	YW	2	designed the study and discussed the manuscript	designed the study and discussed the manuscript	Conceived and designed the experiments	Methodology	YES
4414608	25923913	AF	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414608	25923913	AP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414608	25923913	AP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414608	25923913	AP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414608	25923913	AP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414608	25923913	JB	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4414608	25923913	JB	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4414608	25923913	PM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414608	25923913	PM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414608	25923913	PM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5209304	28050857	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5209304	28050857	CP	2	identification of bacterial species|designed the experiments	identification of bacterial species	Performed the experiments	Investigation	YES
5209304	28050857	CP	2	identification of bacterial species|designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5209304	28050857	JGH	2	antimicrobial spectrum analysis	antimicrobial spectrum analysis	Performed the experiments	Investigation	YES
5209304	28050857	PB	2	perform the majority of the experiments|designed the experiments|drafted the manuscript	perform the majority of the experiments	Performed the experiments	Investigation	YES
5209304	28050857	PB	2	perform the majority of the experiments|designed the experiments|drafted the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5209304	28050857	PB	2	perform the majority of the experiments|designed the experiments|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5209304	28050857	RWS	2	designed the experiments|drafted the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5209304	28050857	RWS	2	designed the experiments|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
1920558	17653279	AT	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1920558	17653279	AT	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1920558	17653279	BT	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1920558	17653279	BT	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1920558	17653279	DV	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1920558	17653279	DV	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1920558	17653279	DV	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1920558	17653279	LJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1920558	17653279	LJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1920558	17653279	LJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1920558	17653279	LJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1920558	17653279	MS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1920558	17653279	MS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5742319	29326745	All authors	2	listed have made a substantial, direct and intellectual contribution to the work, and approved it for publication	listed have made a substantial, direct and intellectual contribution to the work, and approved it for publication	-	-	NO
4414609	25923922	J. Xiao	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4414609	25923922	J. Xing	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4414609	25923922	JQ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414609	25923922	JQ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414609	25923922	RL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414609	25923922	RL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414609	25923922	RL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414609	25923922	RL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414609	25923922	RL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414609	25923922	SZ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414609	25923922	XJL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414609	25923922	XJL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414609	25923922	XPJ	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414609	25923922	XPJ	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414609	25923922	XS	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4414609	25923922	XTQ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4414609	25923922	XYZ	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4414609	25923922	YFX	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5648452	29047329	G.X.	PLoS52	conducted the study|performed the experiments|performed the dna extraction and illumina sequencing|performed the bioinformatic analyses	conducted the study	Performed the experiments	Investigation	YES
5648452	29047329	G.X.	PLoS52	conducted the study|performed the experiments|performed the dna extraction and illumina sequencing|performed the bioinformatic analyses	performed the experiments	Performed the experiments	Investigation	YES
5648452	29047329	G.X.	PLoS52	conducted the study|performed the experiments|performed the dna extraction and illumina sequencing|performed the bioinformatic analyses	performed the dna extraction and illumina sequencing	Performed the experiments	Investigation	YES
5648452	29047329	G.X.	PLoS52	conducted the study|performed the experiments|performed the dna extraction and illumina sequencing|performed the bioinformatic analyses	performed the bioinformatic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5648452	29047329	J.Z.	PLoS52	performed the bioinformatic analyses	performed the bioinformatic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5648452	29047329	L.P.	PLoS52	performed the bioinformatic analyses	performed the bioinformatic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5648452	29047329	L.S.	PLoS52	conducted the study|performed the dna extraction and illumina sequencing|performed the bioinformatic analyses|wrote and edited the manuscript	conducted the study	Performed the experiments	Investigation	YES
5648452	29047329	L.S.	PLoS52	conducted the study|performed the dna extraction and illumina sequencing|performed the bioinformatic analyses|wrote and edited the manuscript	performed the dna extraction and illumina sequencing	Performed the experiments	Investigation	YES
5648452	29047329	L.S.	PLoS52	conducted the study|performed the dna extraction and illumina sequencing|performed the bioinformatic analyses|wrote and edited the manuscript	performed the bioinformatic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5648452	29047329	L.S.	PLoS52	conducted the study|performed the dna extraction and illumina sequencing|performed the bioinformatic analyses|wrote and edited the manuscript	wrote and edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5648452	29047329	L.X.	PLoS52	performed the bioinformatic analyses|wrote and edited the manuscript	performed the bioinformatic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5648452	29047329	L.X.	PLoS52	performed the bioinformatic analyses|wrote and edited the manuscript	wrote and edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5648452	29047329	O.Z.	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5648452	29047329	P.Y.	PLoS52	conducted the study|wrote and edited the manuscript	conducted the study	Performed the experiments	Investigation	YES
5648452	29047329	P.Y.	PLoS52	conducted the study|wrote and edited the manuscript	wrote and edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5648452	29047329	W.D.	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5648452	29047329	W.F.	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5648452	29047329	Y.J.	PLoS52	wrote and edited the manuscript	wrote and edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5648452	29047329	Y.Q.	PLoS52	performed the dna extraction and illumina sequencing	performed the dna extraction and illumina sequencing	Performed the experiments	Investigation	YES
5648452	29047329	Z.J.	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5648452	29047329	Z.M.	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
4414610	25923354	FY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414610	25923354	FY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414610	25923354	FY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414610	25923354	FY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414610	25923354	GBX	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414610	25923354	GBX	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414610	25923354	GBX	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414610	25923354	GBX	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414610	25923354	YYC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414610	25923354	YYC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414610	25923354	YYC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414610	25923354	YYC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414610	25923354	YYC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5209305	28050852	AH	PLoS52	performed the research and interpreted the results	performed the research and interpreted the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5209305	28050852	AM	PLoS52	performed the research and interpreted the results|designed the experiments|wrote the paper	performed the research and interpreted the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5209305	28050852	AM	PLoS52	performed the research and interpreted the results|designed the experiments|wrote the paper	designed the experiments	Conceived and designed the experiments	Methodology	YES
5209305	28050852	AM	PLoS52	performed the research and interpreted the results|designed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5209305	28050852	AV	PLoS52	stored at utrecht university library database	stored at utrecht university library database	Contributed reagents/materials/analysis tools	Software	YES
5209305	28050852	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5209305	28050852	BB	PLoS52	performed the research and interpreted the results	performed the research and interpreted the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5209305	28050852	HABW	PLoS52	designed the experiments|wrote the paper	designed the experiments	Conceived and designed the experiments	Methodology	YES
5209305	28050852	HABW	PLoS52	designed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5209305	28050852	HTSB	PLoS52	performed the research and interpreted the results	performed the research and interpreted the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5209305	28050852	LGL	PLoS52	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5209305	28050852	The authors	PLoS52	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
1924601	17668044	BC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1924601	17668044	BC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1924601	17668044	BC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1924601	17668044	EC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1924601	17668044	EC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1924601	17668044	EC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1924601	17668044	EC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1924601	17668044	EC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1924601	17668044	RB	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1924601	17668044	RB	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1924601	17668044	TG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1924601	17668044	TG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5742331	29326729	CH	PLoS52	designed research|performed research|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
5742331	29326729	CH	PLoS52	designed research|performed research|wrote the paper	performed research	Performed the experiments	Investigation	YES
5742331	29326729	CH	PLoS52	designed research|performed research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5742331	29326729	CS	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5742331	29326729	GS	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
5742331	29326729	MM	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5742331	29326729	RS	PLoS52	designed research|performed research|supervised data analysis and interpretation|wrote the paper|critically revised the paper for final publication	designed research	Conceived and designed the experiments	Methodology	YES
5742331	29326729	RS	PLoS52	designed research|performed research|supervised data analysis and interpretation|wrote the paper|critically revised the paper for final publication	performed research	Performed the experiments	Investigation	YES
5742331	29326729	RS	PLoS52	designed research|performed research|supervised data analysis and interpretation|wrote the paper|critically revised the paper for final publication	supervised data analysis and interpretation	Analyzed the data	Formal analysis|Supervision	YES
5742331	29326729	RS	PLoS52	designed research|performed research|supervised data analysis and interpretation|wrote the paper|critically revised the paper for final publication	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5742331	29326729	RS	PLoS52	designed research|performed research|supervised data analysis and interpretation|wrote the paper|critically revised the paper for final publication	critically revised the paper for final publication	Wrote the paper	Writing - Review & Editing	YES
5742331	29326729	RY	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5742331	29326729	SK	PLoS52	performed research|analyzed the data|wrote the paper	performed research	Performed the experiments	Investigation	YES
5742331	29326729	SK	PLoS52	performed research|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5742331	29326729	SK	PLoS52	performed research|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5742331	29326729	TN	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
4414612	25923352	CVM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414612	25923352	CVM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414612	25923352	CVM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414612	25923352	CVM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414612	25923352	FHT	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4414612	25923352	PM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414612	25923352	PM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414612	25923352	PM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414612	25923352	PM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414612	25923352	PP	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414612	25923352	VR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414612	25923352	VR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414612	25923352	VR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414612	25923352	VR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414612	25923352	YS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5648457	29047334	All the authors	2	contributed to the discussion of the results, and also to the text	contributed to the discussion of the results, and also to the text	Wrote the paper	Writing - Original Draft	YES
5648457	29047334	HWS	2	proposed and implemented both the pca and the svm methods, and executed the experiments	proposed and implemented both the pca and the svm methods, and executed the experiments	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5648457	29047334	MEMTW	2	proposed the svm method and discussed the implementation	proposed the svm method and discussed the implementation	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5648457	29047334	MMB	2	proposed and discussed the biological aspects to be considered for predicting lncrnas	proposed and discussed the biological aspects to be considered for predicting lncrnas	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
5648457	29047334	PFS	2	proposed the problem and the experiments	proposed the problem and the experiments	Conceived and designed the experiments	Conceptualization	YES
5648457	29047334	TR	2	proposed and discussed the biological aspects to be considered for predicting lncrnas	proposed and discussed the biological aspects to be considered for predicting lncrnas	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
5209306	28050845	AAL	2	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5209306	28050845	AMS	2	designed and performed the experiments	designed and performed the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5209306	28050845	ASN	2	designed and performed the experiments	designed and performed the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5209306	28050845	ASS	2	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5209306	28050845	AVL	2	designed and performed the experiments	designed and performed the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5209306	28050845	All	2	data is shown in graphs, figures and table	data is shown in graphs, figures and table	-	Visualization	YES
5209306	28050845	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5209306	28050845	MON	2	designed and performed the experiments	designed and performed the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5209306	28050845	MVZ	2	designed and performed the experiments	designed and performed the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5209306	28050845	NGV	2	designed and performed the experiments	designed and performed the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5209306	28050845	OVB	2	designed and performed the experiments	designed and performed the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5209306	28050845	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5209306	28050845	ZAL	2	designed and performed the experiments	designed and performed the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5209306	28050845	ZIA-K	2	designed and performed the experiments	designed and performed the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5209306	28050845	ZIB	2	designed and performed the experiments	designed and performed the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
1924602	17668045	CM	PLoS5	Conceived and designed the experiments|Conceived some experiments|Critically revised the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1924602	17668045	CM	PLoS5	Conceived and designed the experiments|Conceived some experiments|Critically revised the manuscript	Conceived some experiments	Conceived and designed the experiments	Conceptualization	YES
1924602	17668045	CM	PLoS5	Conceived and designed the experiments|Conceived some experiments|Critically revised the manuscript	Critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
1924602	17668045	CT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1924602	17668045	CT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1924602	17668045	CT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1924602	17668045	CT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1924602	17668045	GK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Wrote the first draft of the paper|Designed the study	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1924602	17668045	GK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Wrote the first draft of the paper|Designed the study	Analyzed the data	Analyzed the data	Formal analysis	YES
1924602	17668045	GK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Wrote the first draft of the paper|Designed the study	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1924602	17668045	GK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Wrote the first draft of the paper|Designed the study	Wrote the first draft of the paper	Wrote the paper	Writing - Original Draft	YES
1924602	17668045	GK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Wrote the first draft of the paper|Designed the study	Designed the study	Conceived and designed the experiments	Methodology	YES
1924602	17668045	GM	PLoS5	Contributed reagents/materials/analysis tools|Contributed to the renal fibroblast cell lines and renal tissue samples	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1924602	17668045	GM	PLoS5	Contributed reagents/materials/analysis tools|Contributed to the renal fibroblast cell lines and renal tissue samples	Contributed to the renal fibroblast cell lines and renal tissue samples	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
1924602	17668045	HK	PLoS5	Contributed reagents/materials/analysis tools|Critically involved in the generation of the antisera	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1924602	17668045	HK	PLoS5	Contributed reagents/materials/analysis tools|Critically involved in the generation of the antisera	Critically involved in the generation of the antisera	-	-	NO
1924602	17668045	MK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Participated in the study design|Participated in the patients sample collection	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1924602	17668045	MK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Participated in the study design|Participated in the patients sample collection	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1924602	17668045	MK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Participated in the study design|Participated in the patients sample collection	Participated in the study design	Conceived and designed the experiments	Methodology	YES
1924602	17668045	MK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Participated in the study design|Participated in the patients sample collection	Participated in the patients sample collection	Performed the experiments	Investigation	YES
5742349	29326750	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5742349	29326750	BJ	2	conceived and designed the sequence data analysis, and wrote the manuscript	conceived and designed the sequence data analysis, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
5742349	29326750	CJ	2	conceived and designed the sequence data analysis, and wrote the manuscript	conceived and designed the sequence data analysis, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
5742349	29326750	JZ	2	contributed to data analysis	contributed to data analysis	Analyzed the data	Formal analysis	YES
5742349	29326750	L-QC	2	reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5742349	29326750	LH	2	contributed to data analysis	contributed to data analysis	Analyzed the data	Formal analysis	YES
5742349	29326750	XZ	2	performed the mutation analyses	performed the mutation analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5742349	29326750	YD	2	contributed to data analysis	contributed to data analysis	Analyzed the data	Formal analysis	YES
5742349	29326750	YX	2	conceived and designed the sequence data analysis, and wrote the manuscript	conceived and designed the sequence data analysis, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
5742349	29326750	ZP	2	performed the md analyses	performed the md analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4414613	25923702	EKJ	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414613	25923702	EKJ	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414613	25923702	HCK	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414613	25923702	HCK	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414613	25923702	HK	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4414613	25923702	JSR	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4414613	25923702	JWH	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4414613	25923702	MJJ	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4414613	25923702	TYK	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4414613	25923702	WBK	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4414613	25923702	WGK	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414613	25923702	WGK	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414613	25923702	YKS	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4414613	25923702	YMC	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5209307	28050848	AM	2	designed plus supervised the experiments and contributed to the writing of the manuscript	designed plus supervised the experiments and contributed to the writing of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Original Draft	YES
5209307	28050848	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5209307	28050848	Florian-Alexander Herbst	2	for his help with the protein-sip attempts	for his help with the protein-sip attempts	Performed the experiments	Investigation	YES
5209307	28050848	JP	2	performed the metagenomic analyses of the enrichment cultures	performed the metagenomic analyses of the enrichment cultures	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5209307	28050848	LABGeM	2	team for their efforts with the microscope genome annotation platform	team for their efforts with the microscope genome annotation platform	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5209307	28050848	MD	2	supervised the illumina amplicon-based sequencing and analysis, and provided the corresponding data and sections of the manuscript	supervised the illumina amplicon-based sequencing and analysis, and provided the corresponding data and sections of the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources|Supervision	YES
5209307	28050848	MK	2	designed the general study concept and supervised the experiments and writing of the manuscript	designed the general study concept and supervised the experiments and writing of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Supervision|Writing - Original Draft	YES
5209307	28050848	PAH	2	in complex environments	in complex environments	-	-	NO
5209307	28050848	TB	2	performed and supervised the metagenomic analyses, and contributed to the writing of the manuscript	performed and supervised the metagenomic analyses, and contributed to the writing of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Supervision|Writing - Original Draft	YES
5209307	28050848	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5648474	29047335	JED	2	designed and conducted the study|edited the manuscript	designed and conducted the study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5648474	29047335	JED	2	designed and conducted the study|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5648474	29047335	JFT	2	designed and conducted the study|collected samples and processed the genotypes|wrote the manuscript|edited the manuscript	designed and conducted the study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5648474	29047335	JFT	2	designed and conducted the study|collected samples and processed the genotypes|wrote the manuscript|edited the manuscript	collected samples and processed the genotypes	Performed the experiments	Data curation|Investigation	YES
5648474	29047335	JFT	2	designed and conducted the study|collected samples and processed the genotypes|wrote the manuscript|edited the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5648474	29047335	JFT	2	designed and conducted the study|collected samples and processed the genotypes|wrote the manuscript|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5648474	29047335	JLH	2	designed and conducted the study|conducted bioinformatic analyses of genotypes and sequence variants|wrote the manuscript	designed and conducted the study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5648474	29047335	JLH	2	designed and conducted the study|conducted bioinformatic analyses of genotypes and sequence variants|wrote the manuscript	conducted bioinformatic analyses of genotypes and sequence variants	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5648474	29047335	JLH	2	designed and conducted the study|conducted bioinformatic analyses of genotypes and sequence variants|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5648474	29047335	RDS	2	designed and conducted the study|collected samples and processed the genotypes|processed ngs data|edited the manuscript	designed and conducted the study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5648474	29047335	RDS	2	designed and conducted the study|collected samples and processed the genotypes|processed ngs data|edited the manuscript	collected samples and processed the genotypes	Performed the experiments	Data curation|Investigation	YES
5648474	29047335	RDS	2	designed and conducted the study|collected samples and processed the genotypes|processed ngs data|edited the manuscript	processed ngs data	Analyzed the data	Data curation	YES
5648474	29047335	RDS	2	designed and conducted the study|collected samples and processed the genotypes|processed ngs data|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5742410	29326748	CS	2	conceived and designed the study|carried out the experiments	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5742410	29326748	CS	2	conceived and designed the study|carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5742410	29326748	H-JP	2	provided materials and related information	provided materials and related information	Contributed reagents/materials/analysis tools	Resources	YES
5742410	29326748	HP	2	provided materials and related information	provided materials and related information	Contributed reagents/materials/analysis tools	Resources	YES
5742410	29326748	JJ	2	conceived and designed the study|carried out the experiments|analyzed and interpreted the data|prepared the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5742410	29326748	JJ	2	conceived and designed the study|carried out the experiments|analyzed and interpreted the data|prepared the manuscript	carried out the experiments	Performed the experiments	Investigation	YES
5742410	29326748	JJ	2	conceived and designed the study|carried out the experiments|analyzed and interpreted the data|prepared the manuscript	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5742410	29326748	JJ	2	conceived and designed the study|carried out the experiments|analyzed and interpreted the data|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5742410	29326748	KS	2	conceived and designed the study|carried out the experiments|analyzed and interpreted the data|prepared the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5742410	29326748	KS	2	conceived and designed the study|carried out the experiments|analyzed and interpreted the data|prepared the manuscript	carried out the experiments	Performed the experiments	Investigation	YES
5742410	29326748	KS	2	conceived and designed the study|carried out the experiments|analyzed and interpreted the data|prepared the manuscript	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5742410	29326748	KS	2	conceived and designed the study|carried out the experiments|analyzed and interpreted the data|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5742410	29326748	S-WH	2	provided materials and related information	provided materials and related information	Contributed reagents/materials/analysis tools	Resources	YES
5742410	29326748	SC	2	conceived and designed the study|carried out the experiments|analyzed and interpreted the data|prepared the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5742410	29326748	SC	2	conceived and designed the study|carried out the experiments|analyzed and interpreted the data|prepared the manuscript	carried out the experiments	Performed the experiments	Investigation	YES
5742410	29326748	SC	2	conceived and designed the study|carried out the experiments|analyzed and interpreted the data|prepared the manuscript	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5742410	29326748	SC	2	conceived and designed the study|carried out the experiments|analyzed and interpreted the data|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
1924603	17668047	GF	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1924603	17668047	GF	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1924603	17668047	GW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1924603	17668047	GW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1924603	17668047	GW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1924603	17668047	HJ	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1924603	17668047	HJ	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1924603	17668047	JG	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1924603	17668047	JP	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1924603	17668047	QX	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1924603	17668047	QX	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1924603	17668047	QX	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1924603	17668047	SHa	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1924603	17668047	SHa	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1924603	17668047	SHa	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1924603	17668047	SHa	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1924603	17668047	SHi	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1924603	17668047	SHi	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1924603	17668047	SHi	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1924603	17668047	SHi	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1924603	17668047	SHi	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1924603	17668047	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1924603	17668047	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1924603	17668047	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1924603	17668047	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1924603	17668047	SY	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1924603	17668047	SY	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1924603	17668047	XQ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1924603	17668047	XQ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1924603	17668047	XQ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1924603	17668047	YL	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4414615	25923139	AT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414615	25923139	AT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414615	25923139	AT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414615	25923139	AT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414615	25923139	CE	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414615	25923139	CE	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414615	25923139	CE	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414615	25923139	JMV	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414615	25923139	JMV	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414615	25923139	JMV	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414615	25923139	ODK	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414615	25923139	ODK	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414615	25923139	PH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4414615	25923139	PV	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5648517	29047327	AW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5648517	29047327	AW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5648517	29047327	AW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5648517	29047327	DC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5648517	29047327	EA	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5648517	29047327	EA	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
5648517	29047327	EA	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5648517	29047327	GLT	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5648517	29047327	GLT	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
5648517	29047327	GLT	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5648517	29047327	JB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5648517	29047327	KOS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5648517	29047327	KOS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
5648517	29047327	KOS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5648517	29047327	KOS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5648517	29047327	LK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5648517	29047327	RBE	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5648517	29047327	RBE	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5648517	29047327	RBE	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5648517	29047327	RWS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5648517	29047327	RWS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
5648517	29047327	RWS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5648517	29047327	RWS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5648517	29047327	RWS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5648517	29047327	TF	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
5648517	29047327	TF	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
5648517	29047327	TF	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5209310	28050856	All authors	2	were involved in data interpretation and the writing of the paper|read and approved the final manuscript	were involved in data interpretation and the writing of the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5209310	28050856	All authors	2	were involved in data interpretation and the writing of the paper|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5209310	28050856	BIP	2	designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
5209310	28050856	JFD	2	designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
5209310	28050856	ORA	2	designed the research|preformed all the experiments and data analysis	designed the research	Conceived and designed the experiments	Methodology	YES
5209310	28050856	ORA	2	designed the research|preformed all the experiments and data analysis	preformed all the experiments and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5209310	28050856	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5742411	29326744	CS	3	Collection of data	Collection of data	Performed the experiments	Investigation	YES
5742411	29326744	EE-N	3	Collection of data	Collection of data	Performed the experiments	Investigation	YES
5742411	29326744	EM	3	Conception and design of this study|Analysis and interpretation of the data	Conception and design of this study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5742411	29326744	EM	3	Conception and design of this study|Analysis and interpretation of the data	Analysis and interpretation of the data	Analyzed the data	Formal analysis	YES
5742411	29326744	GS	3	Analysis and interpretation of the data	Analysis and interpretation of the data	Analyzed the data	Formal analysis	YES
5742411	29326744	JMF	3	Collection of data	Collection of data	Performed the experiments	Investigation	YES
5742411	29326744	PM	3	Conception and design of this study|Collection of data|Analysis and interpretation of the data|Drafting of the article	Conception and design of this study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5742411	29326744	PM	3	Conception and design of this study|Collection of data|Analysis and interpretation of the data|Drafting of the article	Collection of data	Performed the experiments	Investigation	YES
5742411	29326744	PM	3	Conception and design of this study|Collection of data|Analysis and interpretation of the data|Drafting of the article	Analysis and interpretation of the data	Analyzed the data	Formal analysis	YES
5742411	29326744	PM	3	Conception and design of this study|Collection of data|Analysis and interpretation of the data|Drafting of the article	Drafting of the article	Wrote the paper	Writing - Original Draft	YES
5742411	29326744	RP	3	Conception and design of this study|Analysis and interpretation of the data	Conception and design of this study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5742411	29326744	RP	3	Conception and design of this study|Analysis and interpretation of the data	Analysis and interpretation of the data	Analyzed the data	Formal analysis	YES
5742411	29326744	RR	3	Conception and design of this study|Analysis and interpretation of the data|Drafting of the article	Conception and design of this study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5742411	29326744	RR	3	Conception and design of this study|Analysis and interpretation of the data|Drafting of the article	Analysis and interpretation of the data	Analyzed the data	Formal analysis	YES
5742411	29326744	RR	3	Conception and design of this study|Analysis and interpretation of the data|Drafting of the article	Drafting of the article	Wrote the paper	Writing - Original Draft	YES
5742411	29326744	all authors	3	Critical revision and final approval of the article	Critical revision and final approval of the article	Wrote the paper	Writing - Review & Editing	YES
1924604	17668048	DM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1924604	17668048	GP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1924604	17668048	GP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1924604	17668048	GP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1924604	17668048	KS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1924604	17668048	KS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1924604	17668048	KS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1924604	17668048	KS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1924604	17668048	RG	PLoS5	Performed the experiments|Analyzed the data|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1924604	17668048	RG	PLoS5	Performed the experiments|Analyzed the data|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1924604	17668048	RG	PLoS5	Performed the experiments|Analyzed the data|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1924604	17668048	RO	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1924604	17668048	SC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1924604	17668048	SC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1924604	17668048	SC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1924604	17668048	SC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414616	25922948	CJJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414616	25922948	CJJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414616	25922948	CJJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414616	25922948	CJJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414616	25922948	CWW	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4414616	25922948	CWW	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414616	25922948	DWC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414616	25922948	DWC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414616	25922948	DWC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414616	25922948	GSH	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414616	25922948	H. Chang	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4414616	25922948	H. Chang	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414616	25922948	H. Chiu	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414616	25922948	H. Chiu	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414616	25922948	HHH	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414616	25922948	KH	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4414616	25922948	KH	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4414616	25922948	TYH	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4414616	25922948	YHL	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4414616	25922948	YHL	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4414616	25922948	YJL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414616	25922948	YJL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414616	25922948	YJL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414616	25922948	YJL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414616	25922948	YJL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5649071	29052505	All authors	2	read and approved the final manuscript|agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5649071	29052505	All authors	2	read and approved the final manuscript|agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	-	-	NO
5649071	29052505	CT	2	made substantial contributions to conception and design of the experiments|made substantial contributions to analysis and interpretation of data|revised the manuscript critically for important intellectual content	made substantial contributions to conception and design of the experiments	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
5649071	29052505	CT	2	made substantial contributions to conception and design of the experiments|made substantial contributions to analysis and interpretation of data|revised the manuscript critically for important intellectual content	made substantial contributions to analysis and interpretation of data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5649071	29052505	CT	2	made substantial contributions to conception and design of the experiments|made substantial contributions to analysis and interpretation of data|revised the manuscript critically for important intellectual content	revised the manuscript critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5649071	29052505	Each author	2	participated sufficiently in the work to take public responsibility for appropriate portions of the content	participated sufficiently in the work to take public responsibility for appropriate portions of the content	-	-	NO
5649071	29052505	HW	2	made substantial contributions to acquisition of data|made substantial contributions to analysis and interpretation of data|performed the validation experiments|revised the manuscript critically for important intellectual content	made substantial contributions to acquisition of data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5649071	29052505	HW	2	made substantial contributions to acquisition of data|made substantial contributions to analysis and interpretation of data|performed the validation experiments|revised the manuscript critically for important intellectual content	made substantial contributions to analysis and interpretation of data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5649071	29052505	HW	2	made substantial contributions to acquisition of data|made substantial contributions to analysis and interpretation of data|performed the validation experiments|revised the manuscript critically for important intellectual content	performed the validation experiments	Performed the experiments	Investigation|Validation	YES
5649071	29052505	HW	2	made substantial contributions to acquisition of data|made substantial contributions to analysis and interpretation of data|performed the validation experiments|revised the manuscript critically for important intellectual content	revised the manuscript critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5649071	29052505	LW	2	made substantial contributions to conception and design of the experiments|made substantial contributions to acquisition of data|made substantial contributions to analysis and interpretation of data|performed the validation experiments|were involved in drafting the manuscript	made substantial contributions to conception and design of the experiments	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
5649071	29052505	LW	2	made substantial contributions to conception and design of the experiments|made substantial contributions to acquisition of data|made substantial contributions to analysis and interpretation of data|performed the validation experiments|were involved in drafting the manuscript	made substantial contributions to acquisition of data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5649071	29052505	LW	2	made substantial contributions to conception and design of the experiments|made substantial contributions to acquisition of data|made substantial contributions to analysis and interpretation of data|performed the validation experiments|were involved in drafting the manuscript	made substantial contributions to analysis and interpretation of data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5649071	29052505	LW	2	made substantial contributions to conception and design of the experiments|made substantial contributions to acquisition of data|made substantial contributions to analysis and interpretation of data|performed the validation experiments|were involved in drafting the manuscript	performed the validation experiments	Performed the experiments	Investigation|Validation	YES
5649071	29052505	LW	2	made substantial contributions to conception and design of the experiments|made substantial contributions to acquisition of data|made substantial contributions to analysis and interpretation of data|performed the validation experiments|were involved in drafting the manuscript	were involved in drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
5649071	29052505	LY	2	made substantial contributions to conception and design of the experiments|made substantial contributions to acquisition of data|made substantial contributions to analysis and interpretation of data|were involved in drafting the manuscript|revised the manuscript critically for important intellectual content	made substantial contributions to conception and design of the experiments	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
5649071	29052505	LY	2	made substantial contributions to conception and design of the experiments|made substantial contributions to acquisition of data|made substantial contributions to analysis and interpretation of data|were involved in drafting the manuscript|revised the manuscript critically for important intellectual content	made substantial contributions to acquisition of data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5649071	29052505	LY	2	made substantial contributions to conception and design of the experiments|made substantial contributions to acquisition of data|made substantial contributions to analysis and interpretation of data|were involved in drafting the manuscript|revised the manuscript critically for important intellectual content	made substantial contributions to analysis and interpretation of data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5649071	29052505	LY	2	made substantial contributions to conception and design of the experiments|made substantial contributions to acquisition of data|made substantial contributions to analysis and interpretation of data|were involved in drafting the manuscript|revised the manuscript critically for important intellectual content	were involved in drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
5649071	29052505	LY	2	made substantial contributions to conception and design of the experiments|made substantial contributions to acquisition of data|made substantial contributions to analysis and interpretation of data|were involved in drafting the manuscript|revised the manuscript critically for important intellectual content	revised the manuscript critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4414618	25923533	MEA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414618	25923533	MEA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414618	25923533	MEA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414618	25923533	MEA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414618	25923533	MF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414618	25923533	MF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414618	25923533	MF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414618	25923533	MT	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414618	25923533	MT	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414618	25923533	NC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414618	25923533	NC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414618	25923533	NC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1924877	17668056	HN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1924877	17668056	HN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1924877	17668056	HN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1924877	17668056	HN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1924877	17668056	HW	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1924877	17668056	HW	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1924877	17668056	JM	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5742420	29326749	AD	PLoS52	conceived and designed the experiments|discussed the findings and interpreted the results	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5742420	29326749	AD	PLoS52	conceived and designed the experiments|discussed the findings and interpreted the results	discussed the findings and interpreted the results	Analyzed the data	Formal analysis	YES
5742420	29326749	HL	PLoS52	conceived and designed the experiments|performed the experimental work|analyzed the data|discussed the findings and interpreted the results|wrote the first draft of the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5742420	29326749	HL	PLoS52	conceived and designed the experiments|performed the experimental work|analyzed the data|discussed the findings and interpreted the results|wrote the first draft of the paper	performed the experimental work	Performed the experiments	Investigation	YES
5742420	29326749	HL	PLoS52	conceived and designed the experiments|performed the experimental work|analyzed the data|discussed the findings and interpreted the results|wrote the first draft of the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5742420	29326749	HL	PLoS52	conceived and designed the experiments|performed the experimental work|analyzed the data|discussed the findings and interpreted the results|wrote the first draft of the paper	discussed the findings and interpreted the results	Analyzed the data	Formal analysis	YES
5742420	29326749	HL	PLoS52	conceived and designed the experiments|performed the experimental work|analyzed the data|discussed the findings and interpreted the results|wrote the first draft of the paper	wrote the first draft of the paper	Wrote the paper	Writing - Original Draft	YES
5742420	29326749	JD	PLoS52	conceived and designed the experiments|performed the experimental work|analyzed the data|discussed the findings and interpreted the results|wrote the first draft of the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5742420	29326749	JD	PLoS52	conceived and designed the experiments|performed the experimental work|analyzed the data|discussed the findings and interpreted the results|wrote the first draft of the paper	performed the experimental work	Performed the experiments	Investigation	YES
5742420	29326749	JD	PLoS52	conceived and designed the experiments|performed the experimental work|analyzed the data|discussed the findings and interpreted the results|wrote the first draft of the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5742420	29326749	JD	PLoS52	conceived and designed the experiments|performed the experimental work|analyzed the data|discussed the findings and interpreted the results|wrote the first draft of the paper	discussed the findings and interpreted the results	Analyzed the data	Formal analysis	YES
5742420	29326749	JD	PLoS52	conceived and designed the experiments|performed the experimental work|analyzed the data|discussed the findings and interpreted the results|wrote the first draft of the paper	wrote the first draft of the paper	Wrote the paper	Writing - Original Draft	YES
5742420	29326749	KD	PLoS52	performed the experimental work|analyzed the data|discussed the findings and interpreted the results	performed the experimental work	Performed the experiments	Investigation	YES
5742420	29326749	KD	PLoS52	performed the experimental work|analyzed the data|discussed the findings and interpreted the results	analyzed the data	Analyzed the data	Formal analysis	YES
5742420	29326749	KD	PLoS52	performed the experimental work|analyzed the data|discussed the findings and interpreted the results	discussed the findings and interpreted the results	Analyzed the data	Formal analysis	YES
5742420	29326749	M-CL	PLoS52	discussed the findings and interpreted the results	discussed the findings and interpreted the results	Analyzed the data	Formal analysis	YES
5742420	29326749	WJ	PLoS52	discussed the findings and interpreted the results	discussed the findings and interpreted the results	Analyzed the data	Formal analysis	YES
3852803	24348153	Waki Sekine	2	contributed equally to this study	contributed equally to this study	-	-	NO
3852803	24348153	Yuji Haraguchi	2	contributed equally to this study	contributed equally to this study	-	-	NO
5209312	28050849	JCY	CRediT	Conception and design|Critical revision of the manuscript|Supervision	Conception and design	Conceived and designed the experiments	Conceptualization	YES
5209312	28050849	JCY	CRediT	Conception and design|Critical revision of the manuscript|Supervision	Critical revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5209312	28050849	JCY	CRediT	Conception and design|Critical revision of the manuscript|Supervision	Supervision	-	Supervision	YES
5209312	28050849	MSR	CRediT	Conception and design|Acquisition of data|Drafting of the manuscript|Critical revision of the manuscript	Conception and design	Conceived and designed the experiments	Conceptualization	YES
5209312	28050849	MSR	CRediT	Conception and design|Acquisition of data|Drafting of the manuscript|Critical revision of the manuscript	Acquisition of data	Performed the experiments	Investigation	YES
5209312	28050849	MSR	CRediT	Conception and design|Acquisition of data|Drafting of the manuscript|Critical revision of the manuscript	Drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
5209312	28050849	MSR	CRediT	Conception and design|Acquisition of data|Drafting of the manuscript|Critical revision of the manuscript	Critical revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5209312	28050849	YHC	CRediT	Conception and design|Acquisition of data|Critical revision of the manuscript	Conception and design	Conceived and designed the experiments	Conceptualization	YES
5209312	28050849	YHC	CRediT	Conception and design|Acquisition of data|Critical revision of the manuscript	Acquisition of data	Performed the experiments	Investigation	YES
5209312	28050849	YHC	CRediT	Conception and design|Acquisition of data|Critical revision of the manuscript	Critical revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5209312	28050849	YSC	CRediT	Acquisition of data	Acquisition of data	Performed the experiments	Investigation	YES
4414619	25923699	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414619	25923699	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414619	25923699	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414619	25923699	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414619	25923699	MK	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4414619	25923699	NKY	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414619	25923699	NKY	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414619	25923699	RS	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414619	25923699	RS	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414619	25923699	RSK	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414619	25923699	RSK	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414619	25923699	SD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414619	25923699	SD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414619	25923699	SD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5651566	29058591	CK	2	conceived the study, participated in its design and coordination and drafted the manuscript	conceived the study, participated in its design and coordination and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
5651566	29058591	GD	2	conceived the study, participated in its design and coordination and drafted the manuscript|performed the experiments and wrote the paper	conceived the study, participated in its design and coordination and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
5651566	29058591	GD	2	conceived the study, participated in its design and coordination and drafted the manuscript|performed the experiments and wrote the paper	performed the experiments and wrote the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5651566	29058591	WY	2	conceived the study, participated in its design and coordination and drafted the manuscript	conceived the study, participated in its design and coordination and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
5651566	29058591	XK	2	reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5651566	29058591	XM	2	advised and analyzed the data	advised and analyzed the data	Analyzed the data	Formal analysis	YES
5651566	29058591	YG	2	performed the experiments and wrote the paper	performed the experiments and wrote the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5651566	29058591	YZ	2	performed the experiments and wrote the paper	performed the experiments and wrote the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
1924878	17668058	DP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1924878	17668058	DP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1924878	17668058	DP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1924878	17668058	DP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1924878	17668058	KT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1924878	17668058	KT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1924878	17668058	KT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1924878	17668058	KT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5209313	28050851	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5209313	28050851	DR	2	planned and undertook all the practical aspects of the manuscript|commented on by all authors	planned and undertook all the practical aspects of the manuscript	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5209313	28050851	DR	2	planned and undertook all the practical aspects of the manuscript|commented on by all authors	commented on by all authors	-	-	NO
5742621	29312419	BM	2	conducted the plant growth experiments	conducted the plant growth experiments	Performed the experiments	Investigation	YES
5742621	29312419	KG	2	conducted the plant growth experiments	conducted the plant growth experiments	Performed the experiments	Investigation	YES
5742621	29312419	PK	2	conceived the research program|conducted the plant growth experiments|wrote the first draft of the article to which all other authors contributed	conceived the research program	Conceived and designed the experiments	Conceptualization	YES
5742621	29312419	PK	2	conceived the research program|conducted the plant growth experiments|wrote the first draft of the article to which all other authors contributed	conducted the plant growth experiments	Performed the experiments	Investigation	YES
5742621	29312419	PK	2	conceived the research program|conducted the plant growth experiments|wrote the first draft of the article to which all other authors contributed	wrote the first draft of the article to which all other authors contributed	Wrote the paper	Writing - Original Draft	YES
4619792	26539482	Fei-Ting Hsu	2	contributed equally to this study	contributed equally to this study	-	-	NO
4619792	26539482	Yu-Chang Liu	2	contributed equally to this study	contributed equally to this study	-	-	NO
4414620	25923356	A-MB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414620	25923356	A-MB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414620	25923356	A-MB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414620	25923356	AB	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414620	25923356	B-JK	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414620	25923356	B-JK	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414620	25923356	EB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414620	25923356	EB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414620	25923356	EB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414620	25923356	GH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4414620	25923356	JB	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4414620	25923356	JB	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4414620	25923356	KvdG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414620	25923356	KvdG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414620	25923356	KvdG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414620	25923356	KvdG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414620	25923356	KvdG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414620	25923356	MvdH	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414620	25923356	MvdH	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414620	25923356	MvdH	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414620	25923356	PL	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4414620	25923356	PL	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4414620	25923356	SA	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414620	25923356	SA	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414620	25923356	WA	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414620	25923356	WA	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5651609	29058583	NR	4	The study was conceived and designed by|The experimental work was carried out by|The data analysis was performed by|The manuscript was written by	The study was conceived and designed by	Conceived and designed the experiments	Conceptualization|Methodology	YES
5651609	29058583	NR	4	The study was conceived and designed by|The experimental work was carried out by|The data analysis was performed by|The manuscript was written by	The experimental work was carried out by	Performed the experiments	Investigation	YES
5651609	29058583	NR	4	The study was conceived and designed by|The experimental work was carried out by|The data analysis was performed by|The manuscript was written by	The data analysis was performed by	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5651609	29058583	NR	4	The study was conceived and designed by|The experimental work was carried out by|The data analysis was performed by|The manuscript was written by	The manuscript was written by	Wrote the paper	Writing - Original Draft	YES
5651609	29058583	TE	4	The study was conceived and designed by|The data analysis was performed by|The manuscript was written by	The study was conceived and designed by	Conceived and designed the experiments	Conceptualization|Methodology	YES
5651609	29058583	TE	4	The study was conceived and designed by|The data analysis was performed by|The manuscript was written by	The data analysis was performed by	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5651609	29058583	TE	4	The study was conceived and designed by|The data analysis was performed by|The manuscript was written by	The manuscript was written by	Wrote the paper	Writing - Original Draft	YES
5651609	29058583	UI	4	The data analysis was performed by|The manuscript was written by	The data analysis was performed by	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5651609	29058583	UI	4	The data analysis was performed by|The manuscript was written by	The manuscript was written by	Wrote the paper	Writing - Original Draft	YES
1924915	17653271	AA	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1924915	17653271	BR	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1924915	17653271	BR	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1924915	17653271	LS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1924915	17653271	LS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1924915	17653271	LS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1924915	17653271	LS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5743010	29312377	IC	1	Contributed to conception or design of the work|Contributed in data analysis and interpretation|Contributed in critical revision of the article|Final approval of the version to be published	Contributed to conception or design of the work	Conceived and designed the experiments	Conceptualization	YES
5743010	29312377	IC	1	Contributed to conception or design of the work|Contributed in data analysis and interpretation|Contributed in critical revision of the article|Final approval of the version to be published	Contributed in data analysis and interpretation	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5743010	29312377	IC	1	Contributed to conception or design of the work|Contributed in data analysis and interpretation|Contributed in critical revision of the article|Final approval of the version to be published	Contributed in critical revision of the article	Wrote the paper	Writing - Review & Editing	YES
5743010	29312377	IC	1	Contributed to conception or design of the work|Contributed in data analysis and interpretation|Contributed in critical revision of the article|Final approval of the version to be published	Final approval of the version to be published	-	-	NO
5743010	29312377	NL	1	Contributed to conception or design of the work|Collected the data|Contributed in data analysis and interpretation|Drafted the article	Contributed to conception or design of the work	Conceived and designed the experiments	Conceptualization	YES
5743010	29312377	NL	1	Contributed to conception or design of the work|Collected the data|Contributed in data analysis and interpretation|Drafted the article	Collected the data	Performed the experiments	Investigation	YES
5743010	29312377	NL	1	Contributed to conception or design of the work|Collected the data|Contributed in data analysis and interpretation|Drafted the article	Contributed in data analysis and interpretation	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5743010	29312377	NL	1	Contributed to conception or design of the work|Collected the data|Contributed in data analysis and interpretation|Drafted the article	Drafted the article	Wrote the paper	Writing - Original Draft	YES
5743010	29312377	RS	1	Contributed in data analysis and interpretation|Drafted the article	Contributed in data analysis and interpretation	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5743010	29312377	RS	1	Contributed in data analysis and interpretation|Drafted the article	Drafted the article	Wrote the paper	Writing - Original Draft	YES
5743010	29312377	YA	1	Contributed to conception or design of the work|Contributed in data analysis and interpretation|Drafted the article	Contributed to conception or design of the work	Conceived and designed the experiments	Conceptualization	YES
5743010	29312377	YA	1	Contributed to conception or design of the work|Contributed in data analysis and interpretation|Drafted the article	Contributed in data analysis and interpretation	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5743010	29312377	YA	1	Contributed to conception or design of the work|Contributed in data analysis and interpretation|Drafted the article	Drafted the article	Wrote the paper	Writing - Original Draft	YES
5209314	28050850	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5209314	28050850	JLS	2	conceived and supervised the study|made manuscript revisions	conceived and supervised the study	Conceived and designed the experiments	Conceptualization|Supervision	YES
5209314	28050850	JLS	2	conceived and supervised the study|made manuscript revisions	made manuscript revisions	Wrote the paper	Writing - Review & Editing	YES
5209314	28050850	JZ	2	conceived and supervised the study|designed experiments and analyzed data|performed experiments|made manuscript revisions	conceived and supervised the study	Conceived and designed the experiments	Conceptualization|Supervision	YES
5209314	28050850	JZ	2	conceived and supervised the study|designed experiments and analyzed data|performed experiments|made manuscript revisions	designed experiments and analyzed data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5209314	28050850	JZ	2	conceived and supervised the study|designed experiments and analyzed data|performed experiments|made manuscript revisions	performed experiments	Performed the experiments	Investigation	YES
5209314	28050850	JZ	2	conceived and supervised the study|designed experiments and analyzed data|performed experiments|made manuscript revisions	made manuscript revisions	Wrote the paper	Writing - Review & Editing	YES
5209314	28050850	KL	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5209314	28050850	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5209314	28050850	XGX	2	designed experiments and analyzed data	designed experiments and analyzed data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5209314	28050850	XLW	2	provided new tools	provided new tools	Contributed reagents/materials/analysis tools	Resources	YES
4414621	25923716	CR	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414621	25923716	CR	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414621	25923716	CY	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414621	25923716	CY	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414621	25923716	DH	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414621	25923716	DH	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414621	25923716	DH	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414621	25923716	DS	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414621	25923716	JW	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414621	25923716	JW	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414621	25923716	JW	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414621	25923716	QD	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414621	25923716	QD	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414621	25923716	QD	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414621	25923716	SD	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414621	25923716	SD	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414621	25923716	SD	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414621	25923716	SI	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414621	25923716	SI	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414621	25923716	TJ	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414621	25923716	TJ	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5651615	29058585	All authors	2	have read and approved the final version of this manuscript	have read and approved the final version of this manuscript	-	-	NO
5651615	29058585	CS	2	performed the experiments and data analyses	performed the experiments and data analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5651615	29058585	DFZ	2	conceived and designed the study|performed the experiments and data analyses|finalised the data|wrote the manuscript and approved the final manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5651615	29058585	DFZ	2	conceived and designed the study|performed the experiments and data analyses|finalised the data|wrote the manuscript and approved the final manuscript	performed the experiments and data analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5651615	29058585	DFZ	2	conceived and designed the study|performed the experiments and data analyses|finalised the data|wrote the manuscript and approved the final manuscript	finalised the data	-	-	NO
5651615	29058585	DFZ	2	conceived and designed the study|performed the experiments and data analyses|finalised the data|wrote the manuscript and approved the final manuscript	wrote the manuscript and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5651615	29058585	GCP	2	wrote the manuscript and approved the final manuscript	wrote the manuscript and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5651615	29058585	JZ	2	performed the experiments and data analyses	performed the experiments and data analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5651615	29058585	XS	2	conceived and designed the study|wrote the manuscript and approved the final manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5651615	29058585	XS	2	conceived and designed the study|wrote the manuscript and approved the final manuscript	wrote the manuscript and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5651615	29058585	XYZ	2	performed the experiments and data analyses	performed the experiments and data analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5651615	29058585	YC	2	performed the experiments and data analyses	performed the experiments and data analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3983681	24473148	All authors	2	contributed reagents, strains and participated in data analysis	contributed reagents, strains and participated in data analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
3983681	24473148	IP	2	contributing to the edition of the text	contributing to the edition of the text	Wrote the paper	Writing - Original Draft	YES
3983681	24473148	RB	2	contributed advice on chip experiments	contributed advice on chip experiments	Performed the experiments	Investigation	YES
3983681	24473148	SJ	2	contributing to the edition of the text	contributing to the edition of the text	Wrote the paper	Writing - Original Draft	YES
5743026	29312415	AM	7	designed all experiments|performed all experiments and analyses|prepared the manuscript	designed all experiments	Conceived and designed the experiments	Methodology	YES
5743026	29312415	AM	7	designed all experiments|performed all experiments and analyses|prepared the manuscript	performed all experiments and analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5743026	29312415	AM	7	designed all experiments|performed all experiments and analyses|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5743026	29312415	BM	7	contributed to the bifc experiment|prepared the manuscript	contributed to the bifc experiment	Performed the experiments	Investigation	YES
5743026	29312415	BM	7	contributed to the bifc experiment|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5743026	29312415	HB	7	identified the alternative transcripts	identified the alternative transcripts	Performed the experiments	Investigation	YES
5743026	29312415	J-BC	7	designed all experiments|prepared the manuscript	designed all experiments	Conceived and designed the experiments	Methodology	YES
5743026	29312415	J-BC	7	designed all experiments|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5209317	28050846	All	2	the data and materials used in the study are publicly available	the data and materials used in the study are publicly available	-	-	NO
5209317	28050846	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5209317	28050846	HWH	2	carried out all the experiments	carried out all the experiments	Performed the experiments	Investigation	YES
5209317	28050846	JTF	2	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5209317	28050846	LRH	2	took charge of the preservation of strain zx01	took charge of the preservation of strain zx01	Performed the experiments	Investigation	YES
5209317	28050846	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5209317	28050846	XZ	2	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5209317	28050846	YBS	2	carried out all the experiments	carried out all the experiments	Performed the experiments	Investigation	YES
5209317	28050846	YZ	2	carried out all the experiments|collected and calculated all data, created the tables and figures and wrote this manuscript	carried out all the experiments	Performed the experiments	Investigation	YES
5209317	28050846	YZ	2	carried out all the experiments|collected and calculated all data, created the tables and figures and wrote this manuscript	collected and calculated all data, created the tables and figures and wrote this manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Visualization|Writing - Original Draft	YES
1925140	17668043	AK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1925140	17668043	BS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1925140	17668043	CB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1925140	17668043	CS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1925140	17668043	CS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1925140	17668043	CS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1925140	17668043	GC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1925140	17668043	JB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1925140	17668043	JR	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1925140	17668043	MM	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1925140	17668043	MM	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1925140	17668043	PB	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1925140	17668043	RR	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1925140	17668043	RR	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1925140	17668043	SG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5651623	29058582	MAK	2	designed the study and set up the experiments|analyzed and interpreted the data|wrote the manuscript	designed the study and set up the experiments	Conceived and designed the experiments|Performed the experiments	Methodology	YES
5651623	29058582	MAK	2	designed the study and set up the experiments|analyzed and interpreted the data|wrote the manuscript	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5651623	29058582	MAK	2	designed the study and set up the experiments|analyzed and interpreted the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5651623	29058582	NH	2	processed the data|analyzed and interpreted the data|wrote the manuscript	processed the data	Analyzed the data	Data curation	YES
5651623	29058582	NH	2	processed the data|analyzed and interpreted the data|wrote the manuscript	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5651623	29058582	NH	2	processed the data|analyzed and interpreted the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4414623	25923719	KI	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414623	25923719	KI	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414623	25923719	KI	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414623	25923719	KI	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414623	25923719	NY	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414623	25923719	SI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414623	25923719	SI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414623	25923719	SI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414623	25923719	SI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414623	25923719	SI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414623	25923719	SO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4414623	25923719	SO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4414623	25923719	SO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4414623	25923719	SO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414623	25923719	SO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4414623	25923719	YA	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4414623	25923719	YY	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1925141	17668057	JA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1925141	17668057	JA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1925141	17668057	JA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1925141	17668057	JR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1925141	17668057	JR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1925141	17668057	JR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1925141	17668057	JR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5209319	28050847	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5209319	28050847	Felix Bischoff	2	for their support	for their support	-	-	NO
5209319	28050847	GK	2	conceived of the study and participated in its design and coordination and helped to draft the manuscript	conceived of the study and participated in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
5209319	28050847	KB	2	provided writing assistance and helped in results analyzing	provided writing assistance and helped in results analyzing	Analyzed the data|Wrote the paper	Formal analysis	YES
5209319	28050847	MB	2	carried out the molecular genetic studies, microorganisms cultivation, enzymatic activity assays and drafted the manuscript	carried out the molecular genetic studies, microorganisms cultivation, enzymatic activity assays and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5209319	28050847	RB	2	participated in the design of the study and provided excellent biochemical knowledge support	participated in the design of the study and provided excellent biochemical knowledge support	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources	YES
5209319	28050847	Sylvane Stegmann	2	for their support	for their support	-	-	NO
5209319	28050847	TR	2	participated in the design of the study	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
5209319	28050847	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5209319	28050847	UH	2	searched for appropriate genes and carried out the molecular genetic studies	searched for appropriate genes and carried out the molecular genetic studies	Performed the experiments	Investigation	YES
3983682	24534090	GK	2	conceived the icp analysis and biological classifiers|designed and conducted the cdk proteomics experiments|wrote the manuscript with input from all authors	conceived the icp analysis and biological classifiers	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
3983682	24534090	GK	2	conceived the icp analysis and biological classifiers|designed and conducted the cdk proteomics experiments|wrote the manuscript with input from all authors	designed and conducted the cdk proteomics experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3983682	24534090	GK	2	conceived the icp analysis and biological classifiers|designed and conducted the cdk proteomics experiments|wrote the manuscript with input from all authors	wrote the manuscript with input from all authors	Wrote the paper	Writing - Original Draft	YES
3983682	24534090	HH	2	designed and conducted the cdk proteomics experiments|supervised research|wrote the manuscript with input from all authors	designed and conducted the cdk proteomics experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3983682	24534090	HH	2	designed and conducted the cdk proteomics experiments|supervised research|wrote the manuscript with input from all authors	supervised research	-	Supervision	YES
3983682	24534090	HH	2	designed and conducted the cdk proteomics experiments|supervised research|wrote the manuscript with input from all authors	wrote the manuscript with input from all authors	Wrote the paper	Writing - Original Draft	YES
3983682	24534090	JR	2	conceived the icp analysis and biological classifiers|designed and conducted the cdk proteomics experiments|supervised research|wrote the manuscript with input from all authors	conceived the icp analysis and biological classifiers	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
3983682	24534090	JR	2	conceived the icp analysis and biological classifiers|designed and conducted the cdk proteomics experiments|supervised research|wrote the manuscript with input from all authors	designed and conducted the cdk proteomics experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3983682	24534090	JR	2	conceived the icp analysis and biological classifiers|designed and conducted the cdk proteomics experiments|supervised research|wrote the manuscript with input from all authors	supervised research	-	Supervision	YES
3983682	24534090	JR	2	conceived the icp analysis and biological classifiers|designed and conducted the cdk proteomics experiments|supervised research|wrote the manuscript with input from all authors	wrote the manuscript with input from all authors	Wrote the paper	Writing - Original Draft	YES
3983682	24534090	NH	2	designed and conducted the cdk proteomics experiments|wrote the manuscript with input from all authors	designed and conducted the cdk proteomics experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3983682	24534090	NH	2	designed and conducted the cdk proteomics experiments|wrote the manuscript with input from all authors	wrote the manuscript with input from all authors	Wrote the paper	Writing - Original Draft	YES
5743649	29312418	All authors	2	listed have made a substantial, direct and intellectual contribution to the work, and approved it for publication	listed have made a substantial, direct and intellectual contribution to the work, and approved it for publication	-	-	NO
5653981	29061109	A. All	2	authors read, interpret and approved the final version of the manuscript	authors read, interpret and approved the final version of the manuscript	Analyzed the data	Formal analysis	YES
5653981	29061109	DA	2	contributed with the designed and optimized the method with intellectual	contributed with the designed and optimized the method with intellectual	Conceived and designed the experiments|Performed the experiments	Methodology	YES
5653981	29061109	JS	2	designed and optimized the method with intellectual|assisted in the experiments	designed and optimized the method with intellectual	Conceived and designed the experiments|Performed the experiments	Methodology	YES
5653981	29061109	JS	2	designed and optimized the method with intellectual|assisted in the experiments	assisted in the experiments	Performed the experiments	Investigation	YES
5653981	29061109	KD	2	contributed with the designed and optimized the method with intellectual|assisted in the experiments	contributed with the designed and optimized the method with intellectual	Conceived and designed the experiments|Performed the experiments	Methodology	YES
5653981	29061109	KD	2	contributed with the designed and optimized the method with intellectual|assisted in the experiments	assisted in the experiments	Performed the experiments	Investigation	YES
5653981	29061109	YZ	2	designed and optimized the method with intellectual|performed the experiments and analyzed the data	designed and optimized the method with intellectual	Conceived and designed the experiments|Performed the experiments	Methodology	YES
5653981	29061109	YZ	2	designed and optimized the method with intellectual|performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6115686	30310584	A.V.	2	designed and performed the zeolite syntheses and catalytic experiments	designed and performed the zeolite syntheses and catalytic experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6115686	30310584	All authors	2	contributed extensively to the work presented in this paper	contributed extensively to the work presented in this paper	-	-	NO
6115686	30310584	B.L.	2	designed and performed the zeolite syntheses and catalytic experiments|analysed output data, wrote the manuscript and financed the project	designed and performed the zeolite syntheses and catalytic experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6115686	30310584	B.L.	2	designed and performed the zeolite syntheses and catalytic experiments|analysed output data, wrote the manuscript and financed the project	analysed output data, wrote the manuscript and financed the project	Analyzed the data|Wrote the paper	Formal analysis|Funding acquisition|Writing - Original Draft	YES
6115686	30310584	C.C.	2	carried out the theoretical calculations	carried out the theoretical calculations	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6115686	30310584	E.S.G.	2	designed and performed the zeolite syntheses and catalytic experiments	designed and performed the zeolite syntheses and catalytic experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6115686	30310584	M.G.W.	2	performed the high resolution electronic microscopy study	performed the high resolution electronic microscopy study	Performed the experiments	Investigation	YES
6115686	30310584	P.L.	2	designed and performed the zeolite syntheses and catalytic experiments	designed and performed the zeolite syntheses and catalytic experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6115686	30310584	S.S.	2	performed the high resolution electronic microscopy study	performed the high resolution electronic microscopy study	Performed the experiments	Investigation	YES
5209320	28050853	ASA	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5209320	28050853	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5209320	28050853	LJV	PLoS52	designed and performed the experiment and wrote the manuscript	designed and performed the experiment and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5209320	28050853	RPM	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5209320	28050853	TA	PLoS52	designed and performed the experiment and wrote the manuscript	designed and performed the experiment and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5743679	29312409	FF	2	assisted the experiment	assisted the experiment	Performed the experiments	Investigation	YES
5743679	29312409	HS	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5743679	29312409	JL	2	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5743679	29312409	QZ	2	designed the experiment and wrote the paper	designed the experiment and wrote the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4415758	25928540	FK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4415758	25928540	JT	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4415758	25928540	JX	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4415758	25928540	LH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4415758	25928540	LW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415758	25928540	LW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415758	25928540	LW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415758	25928540	MZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415758	25928540	MZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415758	25928540	MZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415758	25928540	XC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415758	25928540	XC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415758	25928540	XC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415758	25928540	YC	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
3983685	24434184	AS	PLoS52	performed experiments and analyzed the data|provided important tools or techniques|discussed and reviewed the manuscript	performed experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3983685	24434184	AS	PLoS52	performed experiments and analyzed the data|provided important tools or techniques|discussed and reviewed the manuscript	provided important tools or techniques	Contributed reagents/materials/analysis tools	Resources	YES
3983685	24434184	AS	PLoS52	performed experiments and analyzed the data|provided important tools or techniques|discussed and reviewed the manuscript	discussed and reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
3983685	24434184	BL	PLoS52	wrote the manuscript|provided important tools or techniques|discussed and reviewed the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3983685	24434184	BL	PLoS52	wrote the manuscript|provided important tools or techniques|discussed and reviewed the manuscript	provided important tools or techniques	Contributed reagents/materials/analysis tools	Resources	YES
3983685	24434184	BL	PLoS52	wrote the manuscript|provided important tools or techniques|discussed and reviewed the manuscript	discussed and reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
3983685	24434184	CS	PLoS52	performed experiments and analyzed the data	performed experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3983685	24434184	EEP	PLoS52	provided important tools or techniques|discussed and reviewed the manuscript	provided important tools or techniques	Contributed reagents/materials/analysis tools	Resources	YES
3983685	24434184	EEP	PLoS52	provided important tools or techniques|discussed and reviewed the manuscript	discussed and reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
3983685	24434184	ME	PLoS52	provided important tools or techniques|discussed and reviewed the manuscript	provided important tools or techniques	Contributed reagents/materials/analysis tools	Resources	YES
3983685	24434184	ME	PLoS52	provided important tools or techniques|discussed and reviewed the manuscript	discussed and reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
3983685	24434184	MM	PLoS52	wrote the manuscript|provided important tools or techniques|discussed and reviewed the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3983685	24434184	MM	PLoS52	wrote the manuscript|provided important tools or techniques|discussed and reviewed the manuscript	provided important tools or techniques	Contributed reagents/materials/analysis tools	Resources	YES
3983685	24434184	MM	PLoS52	wrote the manuscript|provided important tools or techniques|discussed and reviewed the manuscript	discussed and reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
3983685	24434184	OA	PLoS52	conceived and designed the experiments|performed experiments and analyzed the data|wrote the manuscript|discussed and reviewed the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
3983685	24434184	OA	PLoS52	conceived and designed the experiments|performed experiments and analyzed the data|wrote the manuscript|discussed and reviewed the manuscript	performed experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3983685	24434184	OA	PLoS52	conceived and designed the experiments|performed experiments and analyzed the data|wrote the manuscript|discussed and reviewed the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3983685	24434184	OA	PLoS52	conceived and designed the experiments|performed experiments and analyzed the data|wrote the manuscript|discussed and reviewed the manuscript	discussed and reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
3983685	24434184	RG	PLoS52	wrote the manuscript|provided important tools or techniques|discussed and reviewed the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3983685	24434184	RG	PLoS52	wrote the manuscript|provided important tools or techniques|discussed and reviewed the manuscript	provided important tools or techniques	Contributed reagents/materials/analysis tools	Resources	YES
3983685	24434184	RG	PLoS52	wrote the manuscript|provided important tools or techniques|discussed and reviewed the manuscript	discussed and reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
3983685	24434184	RGE	PLoS52	conceived and designed the experiments|wrote the manuscript|discussed and reviewed the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
3983685	24434184	RGE	PLoS52	conceived and designed the experiments|wrote the manuscript|discussed and reviewed the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3983685	24434184	RGE	PLoS52	conceived and designed the experiments|wrote the manuscript|discussed and reviewed the manuscript	discussed and reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
3983685	24434184	UZ	PLoS52	performed experiments and analyzed the data	performed experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3983685	24434184	VS	PLoS52	provided important tools or techniques|discussed and reviewed the manuscript	provided important tools or techniques	Contributed reagents/materials/analysis tools	Resources	YES
3983685	24434184	VS	PLoS52	provided important tools or techniques|discussed and reviewed the manuscript	discussed and reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5653985	29061120	GH	2	conceived of and designed the study|collected pteropods for the study|analyzed the results and wrote the manuscript	conceived of and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5653985	29061120	GH	2	conceived of and designed the study|collected pteropods for the study|analyzed the results and wrote the manuscript	collected pteropods for the study	Performed the experiments	Investigation	YES
5653985	29061120	GH	2	conceived of and designed the study|collected pteropods for the study|analyzed the results and wrote the manuscript	analyzed the results and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5653985	29061120	KJ	2	collected pteropods for the study|isolated the rna, prepared libraries and performed the bioinformatic analysis|analyzed the results and wrote the manuscript	collected pteropods for the study	Performed the experiments	Investigation	YES
5653985	29061120	KJ	2	collected pteropods for the study|isolated the rna, prepared libraries and performed the bioinformatic analysis|analyzed the results and wrote the manuscript	isolated the rna, prepared libraries and performed the bioinformatic analysis	Performed the experiments	Formal analysis|Investigation	YES
5653985	29061120	KJ	2	collected pteropods for the study|isolated the rna, prepared libraries and performed the bioinformatic analysis|analyzed the results and wrote the manuscript	analyzed the results and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
1925142	17668052	MS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Participated in some of the experiments and in part of the data analysis	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1925142	17668052	MS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Participated in some of the experiments and in part of the data analysis	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1925142	17668052	MS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Participated in some of the experiments and in part of the data analysis	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1925142	17668052	MS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Participated in some of the experiments and in part of the data analysis	Participated in some of the experiments and in part of the data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
1925142	17668052	RR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1925142	17668052	RR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1925142	17668052	RR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1925142	17668052	RR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5743680	29312404	AK	2	designed, performed, analyzed the experiments, and wrote the paper	designed, performed, analyzed the experiments, and wrote the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5743680	29312404	All authors	2	reviewed the results and approved the final version of the manuscript	reviewed the results and approved the final version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5743680	29312404	JT	2	designed, performed, analyzed the experiments, and wrote the paper	designed, performed, analyzed the experiments, and wrote the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5743680	29312404	SL	2	designed, performed, analyzed the experiments, and wrote the paper	designed, performed, analyzed the experiments, and wrote the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5743680	29312404	TX	2	performed the nmr analysis of bleogen pb1	performed the nmr analysis of bleogen pb1	Performed the experiments	Investigation	YES
4619810	26539494	All authors	2	have given final approval of the version to be published	have given final approval of the version to be published	-	-	NO
4619810	26539494	Bei Lin	2	had the idea for this research, took responsibility for the design of this work, and wrote the paper	had the idea for this research, took responsibility for the design of this work, and wrote the paper	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
4619810	26539494	Huimin Wang	2	participated in its design and coordination and helped draft the paper	participated in its design and coordination and helped draft the paper	Conceived and designed the experiments|Wrote the paper	Project administration|Writing - Original Draft	YES
4619810	26539494	Huiyu Zhuang	2	have made substantial contributions in acquisition of date	have made substantial contributions in acquisition of date	-	-	NO
4619810	26539494	Jian Gao	2	participated in its design and coordination and helped draft the paper	participated in its design and coordination and helped draft the paper	Conceived and designed the experiments|Wrote the paper	Project administration|Writing - Original Draft	YES
4619810	26539494	Juanjuan Liu	2	performed all statistical analyses	performed all statistical analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4619810	26539494	Liancheng Zhu	2	performed all statistical analyses	performed all statistical analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4619810	26539494	Mingzi Tan	2	have made substantial contributions in acquisition of date	have made substantial contributions in acquisition of date	-	-	NO
4619810	26539494	Xiao Li	2	had the idea for this research, took responsibility for the design of this work, and wrote the paper	had the idea for this research, took responsibility for the design of this work, and wrote the paper	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
4619810	26539494	Yiping Gao	2	have made substantial contributions in acquisition of date	have made substantial contributions in acquisition of date	-	-	NO
4619810	26539494	Zhenhua Hu	2	participated in its design and coordination and helped draft the paper	participated in its design and coordination and helped draft the paper	Conceived and designed the experiments|Wrote the paper	Project administration|Writing - Original Draft	YES
1925143	17668060	CC	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1925143	17668060	CC	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1925143	17668060	DW	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1925143	17668060	DW	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1925143	17668060	GS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1925143	17668060	GS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1925143	17668060	OM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1925143	17668060	OM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1925143	17668060	OM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1925143	17668060	YG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1925143	17668060	YG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1925143	17668060	YG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5209323	28050844	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5209323	28050844	GL	2	designed the experiment|drafted the manuscript	designed the experiment	Conceived and designed the experiments	Methodology	YES
5209323	28050844	GL	2	designed the experiment|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5209323	28050844	JTM	2	operated the reactors and made analysis|drafted the manuscript	operated the reactors and made analysis	Performed the experiments	Investigation	YES
5209323	28050844	JTM	2	operated the reactors and made analysis|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5209323	28050844	JXN	2	operated the reactors and made analysis	operated the reactors and made analysis	Performed the experiments	Investigation	YES
5209323	28050844	LMM	2	designed the experiment	designed the experiment	Conceived and designed the experiments	Methodology	YES
5209323	28050844	YL	2	designed the experiment	designed the experiment	Conceived and designed the experiments	Methodology	YES
5209323	28050844	YLC	2	operated the reactors and made analysis	operated the reactors and made analysis	Performed the experiments	Investigation	YES
5209323	28050844	ZGG	2	designed the experiment	designed the experiment	Conceived and designed the experiments	Methodology	YES
4415761	25928356	AB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415761	25928356	AB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415761	25928356	AB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415761	25928356	AS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415761	25928356	AS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415761	25928356	AS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415761	25928356	CP	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415761	25928356	JC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415761	25928356	JC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415761	25928356	JM	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4415761	25928356	MB	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415761	25928356	PG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415761	25928356	PG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415761	25928356	RN	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415761	25928356	SU	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415761	25928356	SU	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415761	25928356	SU	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415761	25928356	SW	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5653991	29061108	All authors	2	submitted comments on drafts, and read and approved the final manuscript	submitted comments on drafts, and read and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5653991	29061108	GPZ	2	contributed to the design of the study and interpretation of data	contributed to the design of the study and interpretation of data	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Methodology|Resources	YES
5653991	29061108	HXC	2	contributed to interpretation of data and writing of the manuscript	contributed to interpretation of data and writing of the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
5653991	29061108	HYW	2	contributed to the performing of the study, analysis of data and writing of the manuscript	contributed to the performing of the study, analysis of data and writing of the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft	YES
5653991	29061108	JL	2	contributed to data analysis and writing of the manuscript	contributed to data analysis and writing of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5653991	29061108	JW	2	contributed to data analysis and writing of the manuscript|contributed to the design of the study and interpretation of data	contributed to data analysis and writing of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5653991	29061108	JW	2	contributed to data analysis and writing of the manuscript|contributed to the design of the study and interpretation of data	contributed to the design of the study and interpretation of data	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Methodology|Resources	YES
5653991	29061108	MQZ	2	contributed to the sample collection and data analysis	contributed to the sample collection and data analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5653991	29061108	QHL	2	contributed to interpretation of data and writing of the manuscript	contributed to interpretation of data and writing of the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
5653991	29061108	RRL	2	contributed to the design and performing of the study, the interpretation of data, and writing of the manuscript	contributed to the design and performing of the study, the interpretation of data, and writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
5653991	29061108	SYX	2	contributed to the sample collection and data analysis	contributed to the sample collection and data analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5653991	29061108	TXD	2	contributed to the sample collection and data analysis	contributed to the sample collection and data analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
3983686	24431221	AG	2	performed experiments and analyzed data	performed experiments and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3983686	24431221	BC	2	mentored the study	mentored the study	-	Supervision	YES
3983686	24431221	BEC	2	mentored the study	mentored the study	-	Supervision	YES
3983686	24431221	CZ	2	performed experiments and analyzed data	performed experiments and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3983686	24431221	GL	2	performed experiments and analyzed data	performed experiments and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3983686	24431221	GT	2	performed experiments and analyzed data	performed experiments and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3983686	24431221	JN	2	mentored the study	mentored the study	-	Supervision	YES
3983686	24431221	NP	2	performed experiments and analyzed data	performed experiments and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3983686	24431221	OSS	2	mentored the study	mentored the study	-	Supervision	YES
3983686	24431221	SBS	2	performed experiments and analyzed data	performed experiments and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3983686	24431221	SC	2	mentored the study	mentored the study	-	Supervision	YES
3983686	24431221	YS	2	performed experiments and analyzed data	performed experiments and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5743684	29312416	HH	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5743684	29312416	JC	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5743684	29312416	JL	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5743684	29312416	MZ	PLoS52	designed the experiments|performed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5743684	29312416	MZ	PLoS52	designed the experiments|performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5743684	29312416	TW	PLoS52	designed the experiments|performed the experiments|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5743684	29312416	TW	PLoS52	designed the experiments|performed the experiments|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5743684	29312416	TW	PLoS52	designed the experiments|performed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5743684	29312416	XH	PLoS52	designed the experiments|wrote the manuscript|revised the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5743684	29312416	XH	PLoS52	designed the experiments|wrote the manuscript|revised the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5743684	29312416	XH	PLoS52	designed the experiments|wrote the manuscript|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5743684	29312416	YC	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
4619811	26539508	Xiao-Dong Zou	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
4619811	26539508	Yiu-Cho Chung	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
4415762	25927600	JT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415762	25927600	JT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415762	25927600	JT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415762	25927600	JT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415762	25927600	MA	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415762	25927600	MA	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415762	25927600	ME	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415762	25927600	ME	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415762	25927600	ME	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415762	25927600	ME	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1925144	17668053	AH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1925144	17668053	AH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1925144	17668053	AH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1925144	17668053	DM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1925144	17668053	DM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1925144	17668053	DM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1925144	17668053	DM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1925144	17668053	KS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1925144	17668053	KS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1925144	17668053	KS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1925144	17668053	KS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1925144	17668053	KS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1925144	17668053	YS	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1925144	17668053	YT	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1925144	17668053	YT	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5209325	28050842	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5209325	28050842	MHS	PLoS52	conceived and designed the experiments|analyzed data and co-wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5209325	28050842	MHS	PLoS52	conceived and designed the experiments|analyzed data and co-wrote the manuscript	analyzed data and co-wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5209325	28050842	MZ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5209325	28050842	SDL	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5209325	28050842	ZBS	PLoS52	performed the experiments|analyzed data and co-wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5209325	28050842	ZBS	PLoS52	performed the experiments|analyzed data and co-wrote the manuscript	analyzed data and co-wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5743704	29312413	All authors	2	participated in the design of the experiments as well as the analysis/evaluation of the results	participated in the design of the experiments as well as the analysis/evaluation of the results	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5743704	29312413	MG	2	drafted the initial manuscript and all authors participated in the editing and approved its final version	drafted the initial manuscript and all authors participated in the editing and approved its final version	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5743704	29312413	NG	2	drafted the initial manuscript and all authors participated in the editing and approved its final version	drafted the initial manuscript and all authors participated in the editing and approved its final version	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3983687	24488179	CPP	2	conceived the study|interpreted data and wrote the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
3983687	24488179	CPP	2	conceived the study|interpreted data and wrote the manuscript	interpreted data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3983687	24488179	KWV	2	conceived the study|interpreted data and wrote the manuscript|performed experiments	conceived the study	Conceived and designed the experiments	Conceptualization	YES
3983687	24488179	KWV	2	conceived the study|interpreted data and wrote the manuscript|performed experiments	interpreted data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3983687	24488179	KWV	2	conceived the study|interpreted data and wrote the manuscript|performed experiments	performed experiments	Performed the experiments	Investigation	YES
3983687	24488179	LK	2	conducted est profiling	conducted est profiling	Performed the experiments	Investigation	YES
3983687	24488179	PLO	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
3983687	24488179	SEC	2	provided reagents	provided reagents	Contributed reagents/materials/analysis tools	Resources	YES
3983687	24488179	SL	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
3983687	24488179	SNS	2	interpreted data and wrote the manuscript	interpreted data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3983687	24488179	VC	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5654045	29061117	AZ	PLoS5	Conceived and designed the experiments|Analysed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5654045	29061117	AZ	PLoS5	Conceived and designed the experiments|Analysed the data	Analysed the data	Analyzed the data	Formal analysis	YES
5654045	29061117	DN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analysed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5654045	29061117	DN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analysed the data	Performed the experiments	Performed the experiments	Investigation	YES
5654045	29061117	DN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analysed the data	Analysed the data	Analyzed the data	Formal analysis	YES
5654045	29061117	MIF	PLoS5	Conceived and designed the experiments|Analysed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5654045	29061117	MIF	PLoS5	Conceived and designed the experiments|Analysed the data	Analysed the data	Analyzed the data	Formal analysis	YES
5654045	29061117	RS	PLoS5	Analysed the data	Analysed the data	Analyzed the data	Formal analysis	YES
5743732	29312412	AE	PLoS52	performed research|analyzed data	performed research	Performed the experiments	Investigation	YES
5743732	29312412	AE	PLoS52	performed research|analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5743732	29312412	AV	PLoS52	performed research|analyzed data|wrote the paper	performed research	Performed the experiments	Investigation	YES
5743732	29312412	AV	PLoS52	performed research|analyzed data|wrote the paper	analyzed data	Analyzed the data	Formal analysis	YES
5743732	29312412	AV	PLoS52	performed research|analyzed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5743732	29312412	BA	PLoS52	designed research|performed research|analyzed data|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
5743732	29312412	BA	PLoS52	designed research|performed research|analyzed data|wrote the paper	performed research	Performed the experiments	Investigation	YES
5743732	29312412	BA	PLoS52	designed research|performed research|analyzed data|wrote the paper	analyzed data	Analyzed the data	Formal analysis	YES
5743732	29312412	BA	PLoS52	designed research|performed research|analyzed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5743732	29312412	CZ	PLoS52	performed research|wrote the paper	performed research	Performed the experiments	Investigation	YES
5743732	29312412	CZ	PLoS52	performed research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5743732	29312412	LH	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
5743732	29312412	SP	PLoS52	designed research|analyzed data|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
5743732	29312412	SP	PLoS52	designed research|analyzed data|wrote the paper	analyzed data	Analyzed the data	Formal analysis	YES
5743732	29312412	SP	PLoS52	designed research|analyzed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5743732	29312412	SRC	PLoS52	designed research|performed research|analyzed data|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
5743732	29312412	SRC	PLoS52	designed research|performed research|analyzed data|wrote the paper	performed research	Performed the experiments	Investigation	YES
5743732	29312412	SRC	PLoS52	designed research|performed research|analyzed data|wrote the paper	analyzed data	Analyzed the data	Formal analysis	YES
5743732	29312412	SRC	PLoS52	designed research|performed research|analyzed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
1925145	17668061	AP	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1925145	17668061	CC	PLoS5	Performed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1925145	17668061	CC	PLoS5	Performed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1925145	17668061	CC	PLoS5	Performed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1925145	17668061	FB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1925145	17668061	FS	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1925145	17668061	FS	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1925145	17668061	JM	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1925145	17668061	JM	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1925145	17668061	JS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1925145	17668061	JS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1925145	17668061	MF	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1925145	17668061	MF	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1925145	17668061	MM	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1925145	17668061	MM	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1925145	17668061	MN	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1925145	17668061	MN	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1925145	17668061	MP	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1925145	17668061	MR	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1925145	17668061	MR	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1925145	17668061	NM	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1925145	17668061	NM	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1925145	17668061	PM	PLoS5	Analyzed the data|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1925145	17668061	PM	PLoS5	Analyzed the data|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1925145	17668061	PM	PLoS5	Analyzed the data|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1925145	17668061	PS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1925145	17668061	RS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1925145	17668061	RS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1925145	17668061	SD	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1925145	17668061	SD	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1925145	17668061	TV	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1925145	17668061	TV	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5654091	29061116	All authors	PLoS52	reviewed and approved the manuscript	reviewed and approved the manuscript	Wrote the paper	Writing - Review & Editing	YES
5654091	29061116	GYL	PLoS52	performed the qrt-pcr experiments	performed the qrt-pcr experiments	Performed the experiments	Investigation	YES
5654091	29061116	HHZ	PLoS52	collected the leaves samples in the culture room	collected the leaves samples in the culture room	Performed the experiments	Investigation	YES
5654091	29061116	JFZ	PLoS52	conceived and designed the experiments|revised the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5654091	29061116	JFZ	PLoS52	conceived and designed the experiments|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5654091	29061116	JWY	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5654091	29061116	MW	PLoS52	cultivated the cotton plants in the field and collected the fiber and ovule samples	cultivated the cotton plants in the field and collected the fiber and ovule samples	Performed the experiments	Investigation	YES
5654091	29061116	SXY	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5654091	29061116	WFP	PLoS52	cultivated the cotton plants in the field and collected the fiber and ovule samples	cultivated the cotton plants in the field and collected the fiber and ovule samples	Performed the experiments	Investigation	YES
5654091	29061116	XHL	PLoS52	performed the data analysis and wrote the manuscript	performed the data analysis and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5654091	29061116	XLL	PLoS52	cultivated the cotton plants in the field and collected the fiber and ovule samples	cultivated the cotton plants in the field and collected the fiber and ovule samples	Performed the experiments	Investigation	YES
5654091	29061116	XSZ	PLoS52	collected the leaves samples in the culture room	collected the leaves samples in the culture room	Performed the experiments	Investigation	YES
5654091	29061116	YHG	PLoS52	performed the qrt-pcr experiments	performed the qrt-pcr experiments	Performed the experiments	Investigation	YES
5209326	28050855	All authors	2	were involved in data interpretation and the writing of the paper|read and approved the final manuscript	were involved in data interpretation and the writing of the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5209326	28050855	All authors	2	were involved in data interpretation and the writing of the paper|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5209326	28050855	CLH	2	designed research|contributed data analysis	designed research	Conceived and designed the experiments	Methodology	YES
5209326	28050855	CLH	2	designed research|contributed data analysis	contributed data analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5209326	28050855	CZ	2	designed research|preformed all experiments	designed research	Conceived and designed the experiments	Methodology	YES
5209326	28050855	CZ	2	designed research|preformed all experiments	preformed all experiments	Performed the experiments	Investigation	YES
5209326	28050855	TL	2	preformed all experiments	preformed all experiments	Performed the experiments	Investigation	YES
5209326	28050855	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5209326	28050855	XYS	2	designed research|preformed all experiments|contributed data analysis	designed research	Conceived and designed the experiments	Methodology	YES
5209326	28050855	XYS	2	designed research|preformed all experiments|contributed data analysis	preformed all experiments	Performed the experiments	Investigation	YES
5209326	28050855	XYS	2	designed research|preformed all experiments|contributed data analysis	contributed data analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
4415766	25928057	DZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4415766	25928057	HL	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415766	25928057	HL	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415766	25928057	JW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415766	25928057	JW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415766	25928057	JW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415766	25928057	JW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415766	25928057	SG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4415766	25928057	SY	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4415766	25928057	WL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415766	25928057	Y. Li	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4415766	25928057	Y. Lv	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4415766	25928057	Y. Zhao	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4415766	25928057	Y. Zuo	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4415766	25928057	YW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4415766	25928057	ZW	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5743801	29312414	AD	2	performed the experiments with	performed the experiments with	Performed the experiments	Investigation	YES
5743801	29312414	AO	2	performed the experiments with	performed the experiments with	Performed the experiments	Investigation	YES
5743801	29312414	All authors	2	analyzed, interpreted, and discussed the results and contributed to writing of the manuscript	analyzed, interpreted, and discussed the results and contributed to writing of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5743801	29312414	KM	2	performed the experiments with	performed the experiments with	Performed the experiments	Investigation	YES
5743801	29312414	MU	2	performed the experiments with	performed the experiments with	Performed the experiments	Investigation	YES
5743801	29312414	WS	2	assisted with the performed the experiments with	assisted with the performed the experiments with	Performed the experiments	Investigation	YES
1925146	17668062	AS	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1925146	17668062	GS	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1925146	17668062	GS	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1925146	17668062	MM	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1925146	17668062	NT	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1925146	17668062	TG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1925146	17668062	TG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1925146	17668062	TG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1925146	17668062	TG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3989650	24514026	AL	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
3989650	24514026	APJ	PLoS52	analysed data|planned the project/supervised experiments|wrote the manuscript with	analysed data	Analyzed the data	Formal analysis	YES
3989650	24514026	APJ	PLoS52	analysed data|planned the project/supervised experiments|wrote the manuscript with	planned the project/supervised experiments	Conceived and designed the experiments	Conceptualization|Supervision	YES
3989650	24514026	APJ	PLoS52	analysed data|planned the project/supervised experiments|wrote the manuscript with	wrote the manuscript with	Wrote the paper	Writing - Original Draft	YES
3989650	24514026	AR	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
3989650	24514026	ASM	PLoS52	analysed data|planned the project/supervised experiments|helped with the wrote the manuscript with	analysed data	Analyzed the data	Formal analysis	YES
3989650	24514026	ASM	PLoS52	analysed data|planned the project/supervised experiments|helped with the wrote the manuscript with	planned the project/supervised experiments	Conceived and designed the experiments	Conceptualization|Supervision	YES
3989650	24514026	ASM	PLoS52	analysed data|planned the project/supervised experiments|helped with the wrote the manuscript with	helped with the wrote the manuscript with	Wrote the paper	Writing - Original Draft	YES
3989650	24514026	DJD	PLoS52	developed protocols and provided reagents|helped with the wrote the manuscript with	developed protocols and provided reagents	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Methodology|Resources	YES
3989650	24514026	DJD	PLoS52	developed protocols and provided reagents|helped with the wrote the manuscript with	helped with the wrote the manuscript with	Wrote the paper	Writing - Original Draft	YES
3989650	24514026	KJM	PLoS52	performed the experiments|analysed data|helped with the wrote the manuscript with	performed the experiments	Performed the experiments	Investigation	YES
3989650	24514026	KJM	PLoS52	performed the experiments|analysed data|helped with the wrote the manuscript with	analysed data	Analyzed the data	Formal analysis	YES
3989650	24514026	KJM	PLoS52	performed the experiments|analysed data|helped with the wrote the manuscript with	helped with the wrote the manuscript with	Wrote the paper	Writing - Original Draft	YES
3989650	24514026	LMW	PLoS52	performed the experiments|analysed data|helped with the wrote the manuscript with	performed the experiments	Performed the experiments	Investigation	YES
3989650	24514026	LMW	PLoS52	performed the experiments|analysed data|helped with the wrote the manuscript with	analysed data	Analyzed the data	Formal analysis	YES
3989650	24514026	LMW	PLoS52	performed the experiments|analysed data|helped with the wrote the manuscript with	helped with the wrote the manuscript with	Wrote the paper	Writing - Original Draft	YES
3989650	24514026	MAMR	PLoS52	performed the experiments|analysed data|helped with the wrote the manuscript with	performed the experiments	Performed the experiments	Investigation	YES
3989650	24514026	MAMR	PLoS52	performed the experiments|analysed data|helped with the wrote the manuscript with	analysed data	Analyzed the data	Formal analysis	YES
3989650	24514026	MAMR	PLoS52	performed the experiments|analysed data|helped with the wrote the manuscript with	helped with the wrote the manuscript with	Wrote the paper	Writing - Original Draft	YES
3989650	24514026	RER	PLoS52	performed the experiments|analysed data|wrote the manuscript with	performed the experiments	Performed the experiments	Investigation	YES
3989650	24514026	RER	PLoS52	performed the experiments|analysed data|wrote the manuscript with	analysed data	Analyzed the data	Formal analysis	YES
3989650	24514026	RER	PLoS52	performed the experiments|analysed data|wrote the manuscript with	wrote the manuscript with	Wrote the paper	Writing - Original Draft	YES
3989650	24514026	RJL	PLoS52	developed protocols and provided reagents	developed protocols and provided reagents	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Methodology|Resources	YES
3989650	24514026	SD	PLoS52	developed protocols and provided reagents|helped with the wrote the manuscript with	developed protocols and provided reagents	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Methodology|Resources	YES
3989650	24514026	SD	PLoS52	developed protocols and provided reagents|helped with the wrote the manuscript with	helped with the wrote the manuscript with	Wrote the paper	Writing - Original Draft	YES
3989650	24514026	YL	PLoS52	performed the experiments|analysed data	performed the experiments	Performed the experiments	Investigation	YES
3989650	24514026	YL	PLoS52	performed the experiments|analysed data	analysed data	Analyzed the data	Formal analysis	YES
3989650	24514026	YM	PLoS52	planned the project/supervised experiments|helped with the wrote the manuscript with	planned the project/supervised experiments	Conceived and designed the experiments	Conceptualization|Supervision	YES
3989650	24514026	YM	PLoS52	planned the project/supervised experiments|helped with the wrote the manuscript with	helped with the wrote the manuscript with	Wrote the paper	Writing - Original Draft	YES
5209329	28050858	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5209329	28050858	All the authors	PLoS52	conceived the research work	conceived the research work	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5209329	28050858	Biotechnology Research Center	PLoS52	the university of tokyo, for providing research facilities	the university of tokyo, for providing research facilities	-	-	NO
5209329	28050858	CSM	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5209329	28050858	HN	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5209329	28050858	JC	PLoS52	conducted the analyses|analyzed the data|drafted the manuscript	conducted the analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5209329	28050858	JC	PLoS52	conducted the analyses|analyzed the data|drafted the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5209329	28050858	JC	PLoS52	conducted the analyses|analyzed the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5209329	28050858	KO	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5209329	28050858	The authors	PLoS52	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5654107	29061122	AM	2	performed rna sequencing with	performed rna sequencing with	Performed the experiments	Investigation	YES
5654107	29061122	DW	2	interpreted the data and wrote the manuscript	interpreted the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5654107	29061122	GG	2	helped with the and performed rna sequencing with	helped with the and performed rna sequencing with	Performed the experiments	Investigation	YES
5654107	29061122	JM	2	performed most of the experiments with	performed most of the experiments with	Performed the experiments	Investigation	YES
5654107	29061122	MB	2	helped with the performed most of the experiments with	helped with the performed most of the experiments with	Performed the experiments	Investigation	YES
5654107	29061122	OH	2	helped with the performed most of the experiments with	helped with the performed most of the experiments with	Performed the experiments	Investigation	YES
5654107	29061122	SR	2	helped with the performed most of the experiments with	helped with the performed most of the experiments with	Performed the experiments	Investigation	YES
5654107	29061122	TH	2	performed rna sequencing with	performed rna sequencing with	Performed the experiments	Investigation	YES
4415767	25927839	FH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed equally in the preparation on the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415767	25927839	FH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed equally in the preparation on the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415767	25927839	FH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed equally in the preparation on the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415767	25927839	FH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed equally in the preparation on the manuscript	Contributed equally in the preparation on the manuscript	Wrote the paper	Writing - Original Draft	YES
4415767	25927839	MA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed equally in the preparation on the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415767	25927839	MA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed equally in the preparation on the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4415767	25927839	MA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed equally in the preparation on the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4415767	25927839	MA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed equally in the preparation on the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415767	25927839	MA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed equally in the preparation on the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415767	25927839	MA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed equally in the preparation on the manuscript	Contributed equally in the preparation on the manuscript	Wrote the paper	Writing - Original Draft	YES
5743936	29285025	All the authors	2	have made a substantial, direct, intellectual contribution to the work, and reviewed the final version of the manuscript	have made a substantial, direct, intellectual contribution to the work, and reviewed the final version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5743936	29285025	GA	2	initiated the project	initiated the project	Conceived and designed the experiments	Conceptualization	YES
5743936	29285025	KA	2	initiated the project	initiated the project	Conceived and designed the experiments	Conceptualization	YES
5743936	29285025	MM	2	initiated the project	initiated the project	Conceived and designed the experiments	Conceptualization	YES
1925147	17668063	AC	PLoS5	Senior clinical investigator	Senior clinical investigator	-	-	NO
1925147	17668063	AF	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1925147	17668063	AO	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1925147	17668063	AO	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1925147	17668063	AO	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1925147	17668063	AO	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1925147	17668063	BH	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1925147	17668063	BH	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1925147	17668063	CS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1925147	17668063	DA	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1925147	17668063	DG	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Supervised molecular genetics experiments	Performed the experiments	Performed the experiments	Investigation	YES
1925147	17668063	DG	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Supervised molecular genetics experiments	Analyzed the data	Analyzed the data	Formal analysis	YES
1925147	17668063	DG	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Supervised molecular genetics experiments	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1925147	17668063	DG	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Supervised molecular genetics experiments	Supervised molecular genetics experiments	Performed the experiments	Investigation|Supervision	YES
1925147	17668063	HJ	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1925147	17668063	JM	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1925147	17668063	JM	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1925147	17668063	MD	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1925147	17668063	MD	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1925147	17668063	MS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Senior investigator overseeing all molecular genetic aspects of project	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1925147	17668063	MS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Senior investigator overseeing all molecular genetic aspects of project	Analyzed the data	Analyzed the data	Formal analysis	YES
1925147	17668063	MS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Senior investigator overseeing all molecular genetic aspects of project	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1925147	17668063	MS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Senior investigator overseeing all molecular genetic aspects of project	Senior investigator overseeing all molecular genetic aspects of project	Performed the experiments	Investigation|Supervision	YES
1925147	17668063	PD	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1925147	17668063	SB	PLoS5	Performed the experiments|Supervised molecular genetics experiments	Performed the experiments	Performed the experiments	Investigation	YES
1925147	17668063	SB	PLoS5	Performed the experiments|Supervised molecular genetics experiments	Supervised molecular genetics experiments	Performed the experiments	Investigation|Supervision	YES
1925147	17668063	SE	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1925147	17668063	SE	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1925147	17668063	SG	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1925147	17668063	SH	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1925147	17668063	SP	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1925147	17668063	VM	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1925147	17668063	VM	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4158885	24872509	BM	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
4158885	24872509	CVR	2	supervised research	supervised research	-	Supervision	YES
4158885	24872509	EV	2	performed experiments|wrote the manuscript	performed experiments	Performed the experiments	Investigation	YES
4158885	24872509	EV	2	performed experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4158885	24872509	JW	2	designed experiments and led the project|performed experiments|wrote the manuscript	designed experiments and led the project	Conceived and designed the experiments	Methodology	YES
4158885	24872509	JW	2	designed experiments and led the project|performed experiments|wrote the manuscript	performed experiments	Performed the experiments	Investigation	YES
4158885	24872509	JW	2	designed experiments and led the project|performed experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4158885	24872509	LAP	2	designed experiments and led the project|supervised research|conceived and initiated the project|wrote the manuscript	designed experiments and led the project	Conceived and designed the experiments	Methodology	YES
4158885	24872509	LAP	2	designed experiments and led the project|supervised research|conceived and initiated the project|wrote the manuscript	supervised research	-	Supervision	YES
4158885	24872509	LAP	2	designed experiments and led the project|supervised research|conceived and initiated the project|wrote the manuscript	conceived and initiated the project	Conceived and designed the experiments	Conceptualization	YES
4158885	24872509	LAP	2	designed experiments and led the project|supervised research|conceived and initiated the project|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4158885	24872509	MB	2	supervised research	supervised research	-	Supervision	YES
4158885	24872509	MDA	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
4158885	24872509	MS	2	supervised research|wrote the manuscript	supervised research	-	Supervision	YES
4158885	24872509	MS	2	supervised research|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4158885	24872509	SHM	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
4158885	24872509	TMO	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
4158885	24872509	YG	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5744017	29312408	JH	2	conceived the experiments, provided experimental platform, and revised the manuscript	conceived the experiments, provided experimental platform, and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5744017	29312408	LM	2	performed the experiments, analyzed the data, and prepared the manuscript	performed the experiments, analyzed the data, and prepared the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5744017	29312408	LS	2	performed the experiments, analyzed the data, and prepared the manuscript	performed the experiments, analyzed the data, and prepared the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5744017	29312408	YW	2	maintained the experimental platform and attended bench work	maintained the experimental platform and attended bench work	Performed the experiments	Investigation	YES
5744017	29312408	YZ	2	performed the experiments, analyzed the data, and prepared the manuscript	performed the experiments, analyzed the data, and prepared the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
1925148	17668055	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1925148	17668055	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1925148	17668055	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1925148	17668055	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1925148	17668055	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1925148	17668055	MS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1925148	17668055	MS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1925148	17668055	TT	PLoS5	Wrote the paper|Supervised the experiments and analysis|Contributed to analysis|Provided significant insights|Helped in editing and amending the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1925148	17668055	TT	PLoS5	Wrote the paper|Supervised the experiments and analysis|Contributed to analysis|Provided significant insights|Helped in editing and amending the manuscript	Supervised the experiments and analysis	-	Supervision	YES
1925148	17668055	TT	PLoS5	Wrote the paper|Supervised the experiments and analysis|Contributed to analysis|Provided significant insights|Helped in editing and amending the manuscript	Contributed to analysis	-	-	NO
1925148	17668055	TT	PLoS5	Wrote the paper|Supervised the experiments and analysis|Contributed to analysis|Provided significant insights|Helped in editing and amending the manuscript	Provided significant insights	-	-	NO
1925148	17668055	TT	PLoS5	Wrote the paper|Supervised the experiments and analysis|Contributed to analysis|Provided significant insights|Helped in editing and amending the manuscript	Helped in editing and amending the manuscript	Wrote the paper	Writing - Review & Editing	YES
5655832	29065852	EH	1	Study concept and design|Analysis and interpretation of data|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content|Statistical analysis|Obtained funding|Administrative, technical, or material support	Study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5655832	29065852	EH	1	Study concept and design|Analysis and interpretation of data|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content|Statistical analysis|Obtained funding|Administrative, technical, or material support	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
5655832	29065852	EH	1	Study concept and design|Analysis and interpretation of data|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content|Statistical analysis|Obtained funding|Administrative, technical, or material support	Drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
5655832	29065852	EH	1	Study concept and design|Analysis and interpretation of data|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content|Statistical analysis|Obtained funding|Administrative, technical, or material support	Critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5655832	29065852	EH	1	Study concept and design|Analysis and interpretation of data|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content|Statistical analysis|Obtained funding|Administrative, technical, or material support	Statistical analysis	Analyzed the data	Formal analysis	YES
5655832	29065852	EH	1	Study concept and design|Analysis and interpretation of data|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content|Statistical analysis|Obtained funding|Administrative, technical, or material support	Obtained funding	-	Funding acquisition	YES
5655832	29065852	EH	1	Study concept and design|Analysis and interpretation of data|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content|Statistical analysis|Obtained funding|Administrative, technical, or material support	Administrative, technical, or material support	Performed the experiments	Investigation|Project administration	YES
5655832	29065852	GE	1	Study concept and design|Acquisition of data|Analysis and interpretation of data|Critical revision of the manuscript for important intellectual content|Obtained funding|Study supervision	Study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5655832	29065852	GE	1	Study concept and design|Acquisition of data|Analysis and interpretation of data|Critical revision of the manuscript for important intellectual content|Obtained funding|Study supervision	Acquisition of data	Performed the experiments	Investigation	YES
5655832	29065852	GE	1	Study concept and design|Acquisition of data|Analysis and interpretation of data|Critical revision of the manuscript for important intellectual content|Obtained funding|Study supervision	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
5655832	29065852	GE	1	Study concept and design|Acquisition of data|Analysis and interpretation of data|Critical revision of the manuscript for important intellectual content|Obtained funding|Study supervision	Critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5655832	29065852	GE	1	Study concept and design|Acquisition of data|Analysis and interpretation of data|Critical revision of the manuscript for important intellectual content|Obtained funding|Study supervision	Obtained funding	-	Funding acquisition	YES
5655832	29065852	GE	1	Study concept and design|Acquisition of data|Analysis and interpretation of data|Critical revision of the manuscript for important intellectual content|Obtained funding|Study supervision	Study supervision	-	Supervision	YES
5655832	29065852	MP	1	Acquisition of data|Analysis and interpretation of data|Critical revision of the manuscript for important intellectual content|Study supervision	Acquisition of data	Performed the experiments	Investigation	YES
5655832	29065852	MP	1	Acquisition of data|Analysis and interpretation of data|Critical revision of the manuscript for important intellectual content|Study supervision	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
5655832	29065852	MP	1	Acquisition of data|Analysis and interpretation of data|Critical revision of the manuscript for important intellectual content|Study supervision	Critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5655832	29065852	MP	1	Acquisition of data|Analysis and interpretation of data|Critical revision of the manuscript for important intellectual content|Study supervision	Study supervision	-	Supervision	YES
5655832	29065852	MS	1	Acquisition of data|Analysis and interpretation of data|Critical revision of the manuscript for important intellectual content|Administrative, technical, or material support	Acquisition of data	Performed the experiments	Investigation	YES
5655832	29065852	MS	1	Acquisition of data|Analysis and interpretation of data|Critical revision of the manuscript for important intellectual content|Administrative, technical, or material support	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
5655832	29065852	MS	1	Acquisition of data|Analysis and interpretation of data|Critical revision of the manuscript for important intellectual content|Administrative, technical, or material support	Critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5655832	29065852	MS	1	Acquisition of data|Analysis and interpretation of data|Critical revision of the manuscript for important intellectual content|Administrative, technical, or material support	Administrative, technical, or material support	Performed the experiments	Investigation|Project administration	YES
5655832	29065852	OM	1	Study concept and design|Acquisition of data|Analysis and interpretation of data|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content|Statistical analysis|Obtained funding|Administrative, technical, or material support|Study supervision	Study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5655832	29065852	OM	1	Study concept and design|Acquisition of data|Analysis and interpretation of data|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content|Statistical analysis|Obtained funding|Administrative, technical, or material support|Study supervision	Acquisition of data	Performed the experiments	Investigation	YES
5655832	29065852	OM	1	Study concept and design|Acquisition of data|Analysis and interpretation of data|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content|Statistical analysis|Obtained funding|Administrative, technical, or material support|Study supervision	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
5655832	29065852	OM	1	Study concept and design|Acquisition of data|Analysis and interpretation of data|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content|Statistical analysis|Obtained funding|Administrative, technical, or material support|Study supervision	Drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
5655832	29065852	OM	1	Study concept and design|Acquisition of data|Analysis and interpretation of data|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content|Statistical analysis|Obtained funding|Administrative, technical, or material support|Study supervision	Critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5655832	29065852	OM	1	Study concept and design|Acquisition of data|Analysis and interpretation of data|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content|Statistical analysis|Obtained funding|Administrative, technical, or material support|Study supervision	Statistical analysis	Analyzed the data	Formal analysis	YES
5655832	29065852	OM	1	Study concept and design|Acquisition of data|Analysis and interpretation of data|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content|Statistical analysis|Obtained funding|Administrative, technical, or material support|Study supervision	Obtained funding	-	Funding acquisition	YES
5655832	29065852	OM	1	Study concept and design|Acquisition of data|Analysis and interpretation of data|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content|Statistical analysis|Obtained funding|Administrative, technical, or material support|Study supervision	Administrative, technical, or material support	Performed the experiments	Investigation|Project administration	YES
5655832	29065852	OM	1	Study concept and design|Acquisition of data|Analysis and interpretation of data|Drafting of the manuscript|Critical revision of the manuscript for important intellectual content|Statistical analysis|Obtained funding|Administrative, technical, or material support|Study supervision	Study supervision	-	Supervision	YES
5655832	29065852	PA	1	Analysis and interpretation of data|Critical revision of the manuscript for important intellectual content|Statistical analysis	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
5655832	29065852	PA	1	Analysis and interpretation of data|Critical revision of the manuscript for important intellectual content|Statistical analysis	Critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5655832	29065852	PA	1	Analysis and interpretation of data|Critical revision of the manuscript for important intellectual content|Statistical analysis	Statistical analysis	Analyzed the data	Formal analysis	YES
5655832	29065852	WG	1	Acquisition of data|Analysis and interpretation of data|Critical revision of the manuscript for important intellectual content|Administrative, technical, or material support	Acquisition of data	Performed the experiments	Investigation	YES
5655832	29065852	WG	1	Acquisition of data|Analysis and interpretation of data|Critical revision of the manuscript for important intellectual content|Administrative, technical, or material support	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
5655832	29065852	WG	1	Acquisition of data|Analysis and interpretation of data|Critical revision of the manuscript for important intellectual content|Administrative, technical, or material support	Critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5655832	29065852	WG	1	Acquisition of data|Analysis and interpretation of data|Critical revision of the manuscript for important intellectual content|Administrative, technical, or material support	Administrative, technical, or material support	Performed the experiments	Investigation|Project administration	YES
4415768	25928422	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Discussed the results and implications and reviewed the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415768	25928422	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Discussed the results and implications and reviewed the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415768	25928422	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Discussed the results and implications and reviewed the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415768	25928422	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Discussed the results and implications and reviewed the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415768	25928422	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Discussed the results and implications and reviewed the paper	Discussed the results and implications and reviewed the paper	Wrote the paper	Writing - Review & Editing	YES
4415768	25928422	AP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4415768	25928422	MC	PLoS5	Performed the experiments|Discussed the results and implications and reviewed the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415768	25928422	MC	PLoS5	Performed the experiments|Discussed the results and implications and reviewed the paper	Discussed the results and implications and reviewed the paper	Wrote the paper	Writing - Review & Editing	YES
4415768	25928422	MPM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Discussed the results and implications and reviewed the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415768	25928422	MPM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Discussed the results and implications and reviewed the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415768	25928422	MPM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Discussed the results and implications and reviewed the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415768	25928422	MPM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Discussed the results and implications and reviewed the paper	Discussed the results and implications and reviewed the paper	Wrote the paper	Writing - Review & Editing	YES
4415768	25928422	RF	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415768	25928422	SSP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Discussed the results and implications and reviewed the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415768	25928422	SSP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Discussed the results and implications and reviewed the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415768	25928422	SSP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Discussed the results and implications and reviewed the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415768	25928422	SSP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Discussed the results and implications and reviewed the paper	Discussed the results and implications and reviewed the paper	Wrote the paper	Writing - Review & Editing	YES
4415768	25928422	TM	PLoS5	Analyzed the data|Discussed the results and implications and reviewed the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415768	25928422	TM	PLoS5	Analyzed the data|Discussed the results and implications and reviewed the paper	Discussed the results and implications and reviewed the paper	Wrote the paper	Writing - Review & Editing	YES
5209330	28050843	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5209330	28050843	BB	2	corresponding author designed the concept, monitored all experiments and prepared the manuscript	corresponding author designed the concept, monitored all experiments and prepared the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Supervision|Writing - Original Draft	YES
5209330	28050843	BC	2	were involved in procurement of samples from different regions for yeast isolation	were involved in procurement of samples from different regions for yeast isolation	Performed the experiments	Investigation	YES
5209330	28050843	BKK	2	were involved in procurement of samples from different regions for yeast isolation	were involved in procurement of samples from different regions for yeast isolation	Performed the experiments	Investigation	YES
5209330	28050843	BS	2	with the	with the	-	-	NO
5209330	28050843	BSR-RFSMS	2	fellowship to carry out the research work	fellowship to carry out the research work	Performed the experiments	Investigation	YES
5209330	28050843	GSR	2	helped bs with the	helped bs with the	-	-	NO
5209330	28050843	KVK	2	carried out the cytotoxicity assays	carried out the cytotoxicity assays	Performed the experiments	Investigation	YES
5209330	28050843	TAD	2	designed and monitored the cytotoxicity experiments	designed and monitored the cytotoxicity experiments	Conceived and designed the experiments	Methodology|Supervision	YES
5209330	28050843	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
4158905	24986880	All authors	2	contributed to design and interpretation of experiments and writing the manuscript	contributed to design and interpretation of experiments and writing the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4158905	24986880	HH	2	performed and analysed in vitro motility assays	performed and analysed in vitro motility assays	Performed the experiments	Investigation	YES
4158905	24986880	LU	2	purified native dynein and dynactin and performed negative stain electron microscopy	purified native dynein and dynactin and performed negative stain electron microscopy	Performed the experiments	Investigation	YES
4158905	24986880	MS	2	produced baculovirus constructs and expressed and purified the recombinant dynein complex and bicd2n	produced baculovirus constructs and expressed and purified the recombinant dynein complex and bicd2n	Performed the experiments	Investigation	YES
1925149	17668066	EH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1925149	17668066	EH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1925149	17668066	EH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1925149	17668066	JB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1925149	17668066	JB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1925149	17668066	JB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4619817	26539496	Adam Cornish	2	designed the study, performed all analyses, made the figures, and wrote the paper	designed the study, performed all analyses, made the figures, and wrote the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Visualization|Writing - Original Draft	YES
4619817	26539496	Chittibabu Guda	2	provided essential feedback on improvements to the paper and input on the analyses themselves and thoroughly edited the paper	provided essential feedback on improvements to the paper and input on the analyses themselves and thoroughly edited the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5744018	29312411	CL	2	designed the research|performed the research|analyzed data and wrote the paper	designed the research	Conceived and designed the experiments	Methodology	YES
5744018	29312411	CL	2	designed the research|performed the research|analyzed data and wrote the paper	performed the research	Performed the experiments	Investigation	YES
5744018	29312411	CL	2	designed the research|performed the research|analyzed data and wrote the paper	analyzed data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5744018	29312411	DL	2	designed the research|analyzed data and wrote the paper	designed the research	Conceived and designed the experiments	Methodology	YES
5744018	29312411	DL	2	designed the research|analyzed data and wrote the paper	analyzed data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5744018	29312411	FY	2	designed the research|performed the research|analyzed data and wrote the paper	designed the research	Conceived and designed the experiments	Methodology	YES
5744018	29312411	FY	2	designed the research|performed the research|analyzed data and wrote the paper	performed the research	Performed the experiments	Investigation	YES
5744018	29312411	FY	2	designed the research|performed the research|analyzed data and wrote the paper	analyzed data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5744018	29312411	HT	2	performed the research	performed the research	Performed the experiments	Investigation	YES
5744018	29312411	LC	2	designed the research|analyzed data and wrote the paper	designed the research	Conceived and designed the experiments	Methodology	YES
5744018	29312411	LC	2	designed the research|analyzed data and wrote the paper	analyzed data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5744018	29312411	LT	2	performed the research|analyzed data and wrote the paper	performed the research	Performed the experiments	Investigation	YES
5744018	29312411	LT	2	performed the research|analyzed data and wrote the paper	analyzed data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5744018	29312411	SL	2	designed the research|analyzed data and wrote the paper	designed the research	Conceived and designed the experiments	Methodology	YES
5744018	29312411	SL	2	designed the research|analyzed data and wrote the paper	analyzed data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5744018	29312411	XhH	2	performed the research	performed the research	Performed the experiments	Investigation	YES
5744018	29312411	XyH	2	performed the research	performed the research	Performed the experiments	Investigation	YES
5744018	29312411	ZX	2	performed the research	performed the research	Performed the experiments	Investigation	YES
5655900	29065857	AJ	2	prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5655900	29065857	AS	2	implemented the file upload module	implemented the file upload module	Performed the experiments	Investigation	YES
5655900	29065857	GS	2	designed the web application|implemented the workflow	designed the web application	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
5655900	29065857	GS	2	designed the web application|implemented the workflow	implemented the workflow	Performed the experiments	Investigation|Methodology	YES
5655900	29065857	KA	2	conceived and supervised this work|prepared the manuscript	conceived and supervised this work	Conceived and designed the experiments	Conceptualization|Supervision	YES
5655900	29065857	KA	2	conceived and supervised this work|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5655900	29065857	SK	2	designed the web application	designed the web application	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
5655900	29065857	VJ	2	designed the web application|implemented the workflow|prepared the manuscript	designed the web application	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
5655900	29065857	VJ	2	designed the web application|implemented the workflow|prepared the manuscript	implemented the workflow	Performed the experiments	Investigation|Methodology	YES
5655900	29065857	VJ	2	designed the web application|implemented the workflow|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5216010	28058634	AS	2	conceived the idea and designed the experiments	conceived the idea and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5216010	28058634	All authors	2	contributed to discussion of the results|read and approved the final manuscript	contributed to discussion of the results	-	-	NO
5216010	28058634	All authors	2	contributed to discussion of the results|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5216010	28058634	BKA	2	conceived the idea and designed the experiments	conceived the idea and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5216010	28058634	IW	2	conceived the idea and designed the experiments|performed the experiments, analyzed the data and wrote the manuscript	conceived the idea and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5216010	28058634	IW	2	conceived the idea and designed the experiments|performed the experiments, analyzed the data and wrote the manuscript	performed the experiments, analyzed the data and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5216010	28058634	KSB	2	contributed to the design of the experiments	contributed to the design of the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5216010	28058634	MS	2	conceived the idea and designed the experiments|performed the experiments, analyzed the data and wrote the manuscript	conceived the idea and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5216010	28058634	MS	2	conceived the idea and designed the experiments|performed the experiments, analyzed the data and wrote the manuscript	performed the experiments, analyzed the data and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4926098	27357369	All authors	2	contributed to the discussion, reviewed and edited the manuscript, and read and approved the final manuscript	contributed to the discussion, reviewed and edited the manuscript, and read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4926098	27357369	PH	2	acquired the data, and conceived and helped design the study|provided important historical and ethical insights that helped to frame the presentation of the manuscript	acquired the data, and conceived and helped design the study	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
4926098	27357369	PH	2	acquired the data, and conceived and helped design the study|provided important historical and ethical insights that helped to frame the presentation of the manuscript	provided important historical and ethical insights that helped to frame the presentation of the manuscript	-	-	NO
4926098	27357369	RD	2	co-conceived and helped design the study, researched data and wrote the initial draft of the manuscript	co-conceived and helped design the study, researched data and wrote the initial draft of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
4926098	27357369	SA	2	co-conceived and helped design the study|provided important historical and ethical insights that helped to frame the presentation of the manuscript	co-conceived and helped design the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4926098	27357369	SA	2	co-conceived and helped design the study|provided important historical and ethical insights that helped to frame the presentation of the manuscript	provided important historical and ethical insights that helped to frame the presentation of the manuscript	-	-	NO
1925150	17668067	BS	PLoS5	Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1925150	17668067	BS	PLoS5	Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1925150	17668067	BS	PLoS5	Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1925150	17668067	BS	PLoS5	Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1925150	17668067	CS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1925150	17668067	CS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1925150	17668067	CS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1925150	17668067	CS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1925150	17668067	CT	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1925150	17668067	CT	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1925150	17668067	JM	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1925150	17668067	JM	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1925150	17668067	MS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1925150	17668067	MS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1925150	17668067	MS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1925150	17668067	PA	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1925150	17668067	SK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4415769	25927528	AD	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4415769	25927528	AHT	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4415769	25927528	BAN	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4415769	25927528	BCS	PLoS5	Performed the experiments|Reviewed and edited data, results, and manuscripts	Performed the experiments	Performed the experiments	Investigation	YES
4415769	25927528	BCS	PLoS5	Performed the experiments|Reviewed and edited data, results, and manuscripts	Reviewed and edited data, results, and manuscripts	Wrote the paper	Writing - Review & Editing	YES
4415769	25927528	BK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415769	25927528	BK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415769	25927528	BK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415769	25927528	BK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415769	25927528	BK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415769	25927528	EAM	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415769	25927528	EAM	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4415769	25927528	EIKR	PLoS5	Reviewed and edited data, results, and manuscripts	Reviewed and edited data, results, and manuscripts	Wrote the paper	Writing - Review & Editing	YES
4415769	25927528	ES	PLoS5	Conceived and designed the experiments|Performed the experiments|Reviewed and edited data, results, and manuscripts	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415769	25927528	ES	PLoS5	Conceived and designed the experiments|Performed the experiments|Reviewed and edited data, results, and manuscripts	Performed the experiments	Performed the experiments	Investigation	YES
4415769	25927528	ES	PLoS5	Conceived and designed the experiments|Performed the experiments|Reviewed and edited data, results, and manuscripts	Reviewed and edited data, results, and manuscripts	Wrote the paper	Writing - Review & Editing	YES
4415769	25927528	GLF	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415769	25927528	GLF	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415769	25927528	HB	PLoS5	Conceived and designed the experiments|Reviewed and edited data, results, and manuscripts	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415769	25927528	HB	PLoS5	Conceived and designed the experiments|Reviewed and edited data, results, and manuscripts	Reviewed and edited data, results, and manuscripts	Wrote the paper	Writing - Review & Editing	YES
4415769	25927528	JJ	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415769	25927528	JJ	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415769	25927528	JK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415769	25927528	JK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415769	25927528	JK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415769	25927528	JR	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4415769	25927528	JWD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415769	25927528	JWD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415769	25927528	JWD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415769	25927528	LK	PLoS5	Performed the experiments|Performed the experiments|Reviewed and edited data, results, and manuscripts	Performed the experiments	Performed the experiments	Investigation	YES
4415769	25927528	LK	PLoS5	Performed the experiments|Performed the experiments|Reviewed and edited data, results, and manuscripts	Performed the experiments	Performed the experiments	Investigation	YES
4415769	25927528	LK	PLoS5	Performed the experiments|Performed the experiments|Reviewed and edited data, results, and manuscripts	Reviewed and edited data, results, and manuscripts	Wrote the paper	Writing - Review & Editing	YES
4415769	25927528	LS	PLoS5	Performed the experiments|Reviewed and edited data, results, and manuscripts	Performed the experiments	Performed the experiments	Investigation	YES
4415769	25927528	LS	PLoS5	Performed the experiments|Reviewed and edited data, results, and manuscripts	Reviewed and edited data, results, and manuscripts	Wrote the paper	Writing - Review & Editing	YES
4415769	25927528	MAS	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415769	25927528	MAS	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415769	25927528	MB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415769	25927528	MB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415769	25927528	MB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415769	25927528	MB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415769	25927528	NC	PLoS5	Performed the experiments|Analyzed the data|Reviewed and edited data, results, and manuscripts	Performed the experiments	Performed the experiments	Investigation	YES
4415769	25927528	NC	PLoS5	Performed the experiments|Analyzed the data|Reviewed and edited data, results, and manuscripts	Analyzed the data	Analyzed the data	Formal analysis	YES
4415769	25927528	NC	PLoS5	Performed the experiments|Analyzed the data|Reviewed and edited data, results, and manuscripts	Reviewed and edited data, results, and manuscripts	Wrote the paper	Writing - Review & Editing	YES
4415769	25927528	NH	PLoS5	Reviewed and edited data, results, and manuscripts	Reviewed and edited data, results, and manuscripts	Wrote the paper	Writing - Review & Editing	YES
4415769	25927528	NNH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415769	25927528	NNH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4415769	25927528	NNH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4415769	25927528	SRR	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4415769	25927528	SSR	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415769	25927528	TAL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415769	25927528	TAL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415769	25927528	TAL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415769	25927528	VL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4168288	24760698	AIL-C	2	performed research	performed research	Performed the experiments	Investigation	YES
4168288	24760698	BG	2	designed study and supervised work|wrote the manuscript	designed study and supervised work	Conceived and designed the experiments	Methodology|Supervision	YES
4168288	24760698	BG	2	designed study and supervised work|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4168288	24760698	ED	2	performed bioinformatic analysis	performed bioinformatic analysis	Performed the experiments	Formal analysis|Investigation	YES
4168288	24760698	FJC-N	2	designed experiments, performed research and analysed data|wrote the manuscript	designed experiments, performed research and analysed data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
4168288	24760698	FJC-N	2	designed experiments, performed research and analysed data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4168288	24760698	FSN	2	performed bioinformatic analysis|wrote the manuscript	performed bioinformatic analysis	Performed the experiments	Formal analysis|Investigation	YES
4168288	24760698	FSN	2	performed bioinformatic analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4168288	24760698	IJ-M	2	performed research	performed research	Performed the experiments	Investigation	YES
4168288	24760698	LW	2	discussed results and manuscript	discussed results and manuscript	-	-	NO
4168288	24760698	NKW	2	performed research	performed research	Performed the experiments	Investigation	YES
4168288	24760698	RH	2	performed bioinformatic analysis	performed bioinformatic analysis	Performed the experiments	Formal analysis|Investigation	YES
4168288	24760698	VM	2	performed research	performed research	Performed the experiments	Investigation	YES
5657036	29513196	BF	2	work on the data preparation and analysis	work on the data preparation and analysis	Analyzed the data	Formal analysis	YES
5657036	29513196	JT	2	work on the algorithm design	work on the algorithm design	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
5657036	29513196	JZ	2	work on the algorithm design	work on the algorithm design	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
5657036	29513196	LZ	2	work on the algorithm design|work on the experimental design|work on the data preparation and analysis	work on the algorithm design	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
5657036	29513196	LZ	2	work on the algorithm design|work on the experimental design|work on the data preparation and analysis	work on the experimental design	Conceived and designed the experiments	Methodology	YES
5657036	29513196	LZ	2	work on the algorithm design|work on the experimental design|work on the data preparation and analysis	work on the data preparation and analysis	Analyzed the data	Formal analysis	YES
5657036	29513196	YL	2	work on the algorithm design|work on the experimental design|work on the data preparation and analysis	work on the algorithm design	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
5657036	29513196	YL	2	work on the algorithm design|work on the experimental design|work on the data preparation and analysis	work on the experimental design	Conceived and designed the experiments	Methodology	YES
5657036	29513196	YL	2	work on the algorithm design|work on the experimental design|work on the data preparation and analysis	work on the data preparation and analysis	Analyzed the data	Formal analysis	YES
5218947	28063146	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5218947	28063146	JDK	PLoS52	performed the experiments|draft the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5218947	28063146	JDK	PLoS52	performed the experiments|draft the manuscript	draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5218947	28063146	JHS	PLoS52	analyzed the results	analyzed the results	Analyzed the data	Formal analysis	YES
5218947	28063146	MGL	PLoS52	analyzed the results	analyzed the results	Analyzed the data	Formal analysis	YES
5218947	28063146	MIK	PLoS52	performed the experiments|draft the manuscript|analyzed the results	performed the experiments	Performed the experiments	Investigation	YES
5218947	28063146	MIK	PLoS52	performed the experiments|draft the manuscript|analyzed the results	draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5218947	28063146	MIK	PLoS52	performed the experiments|draft the manuscript|analyzed the results	analyzed the results	Analyzed the data	Formal analysis	YES
5744040	29312431	M. The	2	final manuscript was read and approved by all authors	final manuscript was read and approved by all authors	Wrote the paper	Writing - Review & Editing	YES
5744040	29312431	MS	2	conducted the qpcr and some of the southern blot hybridization analyses	conducted the qpcr and some of the southern blot hybridization analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5744040	29312431	RB	2	conceived the study and supervised the work	conceived the study and supervised the work	Conceived and designed the experiments	Conceptualization|Supervision	YES
5744040	29312431	ZI	2	performed the majority of the experimental work	performed the majority of the experimental work	Performed the experiments	Investigation	YES
4619819	26525953	Hagen Frickmann	2	contributed equally to this work	contributed equally to this work	-	-	NO
4619819	26525953	Philipp Warnke	2	contributed equally to this work	contributed equally to this work	-	-	NO
1930150	17668049	DB	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1930150	17668049	DB	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1930150	17668049	DL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1930150	17668049	DL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1930150	17668049	DL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1930150	17668049	DL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1930150	17668049	GD	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1930150	17668049	GD	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1930150	17668049	HC	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1930150	17668049	HC	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1930150	17668049	SM	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Wrote the paper|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1930150	17668049	SM	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Wrote the paper|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1930150	17668049	SM	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Wrote the paper|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1930150	17668049	SM	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Wrote the paper|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4194102	24966277	AU	2	maintained the mouse colony and generated crosses	maintained the mouse colony and generated crosses	Performed the experiments	Investigation	YES
4194102	24966277	JS	2	advised on experimental design and edited the manuscript	advised on experimental design and edited the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
4194102	24966277	JX	2	helped design and conduct the experiments	helped design and conduct the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4194102	24966277	MP	2	helped design and conduct the experiments	helped design and conduct the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4194102	24966277	SC	2	designed and led the study and wrote the manuscript	designed and led the study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5657037	29513195	LZ	2	designed the project, analyzed and interpreted the data|were involved in drafting and revising the manuscript	designed the project, analyzed and interpreted the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5657037	29513195	LZ	2	designed the project, analyzed and interpreted the data|were involved in drafting and revising the manuscript	were involved in drafting and revising the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5657037	29513195	SY	2	were involved in drafting and revising the manuscript	were involved in drafting and revising the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5657037	29513195	VV	2	designed the project, analyzed and interpreted the data|executed the program|were involved in drafting and revising the manuscript	designed the project, analyzed and interpreted the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5657037	29513195	VV	2	designed the project, analyzed and interpreted the data|executed the program|were involved in drafting and revising the manuscript	executed the program	Performed the experiments	Investigation	YES
5657037	29513195	VV	2	designed the project, analyzed and interpreted the data|executed the program|were involved in drafting and revising the manuscript	were involved in drafting and revising the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5744074	29312384	AH	2	conducted the diet assessment|co-wrote the manuscript with significant input from all authors	conducted the diet assessment	Performed the experiments	Investigation	YES
5744074	29312384	AH	2	conducted the diet assessment|co-wrote the manuscript with significant input from all authors	co-wrote the manuscript with significant input from all authors	Wrote the paper	Writing - Original Draft	YES
5744074	29312384	All authors	2	contributed to the development of ideas, collection of literature, and data extraction	contributed to the development of ideas, collection of literature, and data extraction	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Data curation|Formal analysis|Investigation|Resources	YES
5744074	29312384	CH	2	provided unpublished data for inclusion in the meta-analyses	provided unpublished data for inclusion in the meta-analyses	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5744074	29312384	JR	2	conducted the correlation meta-analysis|co-wrote the manuscript with significant input from all authors	conducted the correlation meta-analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5744074	29312384	JR	2	conducted the correlation meta-analysis|co-wrote the manuscript with significant input from all authors	co-wrote the manuscript with significant input from all authors	Wrote the paper	Writing - Original Draft	YES
5744074	29312384	MW	2	conducted the top-down meta-analysis|co-wrote the manuscript with significant input from all authors	conducted the top-down meta-analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5744074	29312384	MW	2	conducted the top-down meta-analysis|co-wrote the manuscript with significant input from all authors	co-wrote the manuscript with significant input from all authors	Wrote the paper	Writing - Original Draft	YES
5744074	29312384	NK	2	conducted the top-down meta-analysis|co-wrote the manuscript with significant input from all authors	conducted the top-down meta-analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5744074	29312384	NK	2	conducted the top-down meta-analysis|co-wrote the manuscript with significant input from all authors	co-wrote the manuscript with significant input from all authors	Wrote the paper	Writing - Original Draft	YES
5744074	29312384	PJ	2	provided unpublished data for inclusion in the meta-analyses	provided unpublished data for inclusion in the meta-analyses	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
4415771	25928744	AW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415771	25928744	AW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415771	25928744	AW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415771	25928744	AW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415771	25928744	AW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415771	25928744	BM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415771	25928744	BM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415771	25928744	BM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415771	25928744	CZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415771	25928744	CZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415771	25928744	CZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415771	25928744	CZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415771	25928744	FR	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415771	25928744	FR	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415771	25928744	FR	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415771	25928744	MP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415771	25928744	MP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415771	25928744	MP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415771	25928744	MP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415771	25928744	MP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415771	25928744	NS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415771	25928744	NS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415771	25928744	NS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415771	25928744	NT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415771	25928744	NT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415771	25928744	NT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415771	25928744	NT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415771	25928744	SI	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415771	25928744	SI	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415771	25928744	SI	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415771	25928744	SK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415771	25928744	SK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415771	25928744	SK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415771	25928744	SK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415771	25928744	SM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415771	25928744	SM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415771	25928744	SM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415771	25928744	TH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415771	25928744	TH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415771	25928744	TH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415771	25928744	TH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5218949	28063148	All	2	animal experiments were compliant with the ethical standards of anhui agricultural university	animal experiments were compliant with the ethical standards of anhui agricultural university	Performed the experiments	Investigation	YES
5218949	28063148	All of the authors	2	have read and approved the final manuscript	have read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5218949	28063148	CB	2	participated in the data collection and analysis	participated in the data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5218949	28063148	DY	2	was involved in the drafting of the manuscript	was involved in the drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
5218949	28063148	GL	2	participated in statistical analysis	participated in statistical analysis	Analyzed the data	Formal analysis	YES
5218949	28063148	GW	2	participated in the research design, and helped draft the manuscript	participated in the research design, and helped draft the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
5218949	28063148	KQ	2	participated in statistical analysis	participated in statistical analysis	Analyzed the data	Formal analysis	YES
5218949	28063148	KY	2	participated in the data collection and analysis	participated in the data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5218949	28063148	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5218949	28063148	YL	2	conceived of the study and revised the manuscript critically	conceived of the study and revised the manuscript critically	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5218949	28063148	YW	2	conceived of the study, performed the experiments, and drafted the manuscript	conceived of the study, performed the experiments, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
1930151	17668050	CC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1930151	17668050	CM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1930151	17668050	CM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1930151	17668050	CM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1930151	17668050	DE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1930151	17668050	DE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1930151	17668050	DE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1930151	17668050	DE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1930151	17668050	HA	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1930151	17668050	JR	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1930151	17668050	JR	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1930151	17668050	JR	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1930151	17668050	RD	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1930151	17668050	RD	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1930151	17668050	TL	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1930151	17668050	TL	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4619821	26539491	Abdel Kareem Azab	2	designed the study, analyzed and interpreted the data, wrote the paper, and supervised the study	designed the study, analyzed and interpreted the data, wrote the paper, and supervised the study	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Supervision|Writing - Original Draft	YES
4619821	26539491	Barbara Muz	2	designed the study, performed experiments, analyzed and interpreted the data, and wrote the paper	designed the study, performed experiments, analyzed and interpreted the data, and wrote the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4619821	26539491	Feda Azab	2	performed experiments, evaluated the data, and reviewed the paper	performed experiments, evaluated the data, and reviewed the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4619821	26539491	Richard Alvarez	2	provided the antibodies and reviewed the paper	provided the antibodies and reviewed the paper	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Resources|Writing - Review & Editing	YES
4619821	26539491	Scott Rollins	2	provided the antibodies and reviewed the paper	provided the antibodies and reviewed the paper	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Resources|Writing - Review & Editing	YES
4619821	26539491	Ziad Kawar	2	provided the antibodies and reviewed the paper	provided the antibodies and reviewed the paper	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Resources|Writing - Review & Editing	YES
4415773	25928420	EBC	PLoS5	Contributed in concept developing and discussion	Contributed in concept developing and discussion	Conceived and designed the experiments	Conceptualization	YES
4415773	25928420	ECC	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415773	25928420	ECC	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415773	25928420	LL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415773	25928420	LL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415773	25928420	LL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415773	25928420	LL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415773	25928420	YG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4415773	25928420	YW	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4415773	25928420	YY	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5657050	29513194	All of the authors	2	contributed to the preparation and approval of the final manuscript	contributed to the preparation and approval of the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5657050	29513194	HFL	2	initiated and designed the study	initiated and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5657050	29513194	JW	2	implemeted the predited method	implemeted the predited method	Performed the experiments|Wrote the paper	Writing - Review & Editing	YES
5657050	29513194	YJZ	2	initiated and designed the study|implemeted the predited method|contributed to the results analysis	initiated and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5657050	29513194	YJZ	2	initiated and designed the study|implemeted the predited method|contributed to the results analysis	implemeted the predited method	Performed the experiments|Wrote the paper	Writing - Review & Editing	YES
5657050	29513194	YJZ	2	initiated and designed the study|implemeted the predited method|contributed to the results analysis	contributed to the results analysis	-	-	NO
5657050	29513194	YWL	2	contributed to the results analysis	contributed to the results analysis	-	-	NO
5657050	29513194	ZHY	2	implemeted the predited method	implemeted the predited method	Performed the experiments|Wrote the paper	Writing - Review & Editing	YES
1930152	17668068	DC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1930152	17668068	JL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1930152	17668068	RB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1930152	17668068	RH	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1930152	17668068	RH	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1930152	17668068	RM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1930152	17668068	RM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1930152	17668068	RM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1930152	17668068	RM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1930152	17668068	RS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1930152	17668068	VA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1930152	17668068	VA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1930152	17668068	VA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1930152	17668068	VA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415774	25927918	BB	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415774	25927918	BB	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415774	25927918	SVK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415774	25927918	SVK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415774	25927918	SVK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415774	25927918	SVK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415774	25927918	ZJ	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5657052	29513198	AQ	2	performed the interpretation of the results and wrote the manuscript	performed the interpretation of the results and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5657052	29513198	BH	2	performed the interpretation of the results and wrote the manuscript	performed the interpretation of the results and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5657052	29513198	JW	2	contributed to the design of the study|performed the implementation of the framework|performed the interpretation of the results and wrote the manuscript	contributed to the design of the study	Conceived and designed the experiments	Methodology	YES
5657052	29513198	JW	2	contributed to the design of the study|performed the implementation of the framework|performed the interpretation of the results and wrote the manuscript	performed the implementation of the framework	Performed the experiments	Investigation	YES
5657052	29513198	JW	2	contributed to the design of the study|performed the implementation of the framework|performed the interpretation of the results and wrote the manuscript	performed the interpretation of the results and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5657052	29513198	XS	2	contributed to the design of the study|performed the interpretation of the results and wrote the manuscript	contributed to the design of the study	Conceived and designed the experiments	Methodology	YES
5657052	29513198	XS	2	contributed to the design of the study|performed the interpretation of the results and wrote the manuscript	performed the interpretation of the results and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5744081	29312426	DI	2	performed the experiments and experimental measures|contributed to the graphical representation of data	performed the experiments and experimental measures	Performed the experiments	Investigation	YES
5744081	29312426	DI	2	performed the experiments and experimental measures|contributed to the graphical representation of data	contributed to the graphical representation of data	Contributed reagents/materials/analysis tools	Resources	YES
5744081	29312426	FM	2	performed the experiments and experimental measures|analyzed and interpreted all the results|contributed to the graphical representation of data	performed the experiments and experimental measures	Performed the experiments	Investigation	YES
5744081	29312426	FM	2	performed the experiments and experimental measures|analyzed and interpreted all the results|contributed to the graphical representation of data	analyzed and interpreted all the results	Analyzed the data	Formal analysis	YES
5744081	29312426	FM	2	performed the experiments and experimental measures|analyzed and interpreted all the results|contributed to the graphical representation of data	contributed to the graphical representation of data	Contributed reagents/materials/analysis tools	Resources	YES
5744081	29312426	GL	2	performed the experiments and experimental measures|contributed to the graphical representation of data	performed the experiments and experimental measures	Performed the experiments	Investigation	YES
5744081	29312426	GL	2	performed the experiments and experimental measures|contributed to the graphical representation of data	contributed to the graphical representation of data	Contributed reagents/materials/analysis tools	Resources	YES
5744081	29312426	MM	2	designed the experiment|performed the experiments and experimental measures|analyzed and interpreted all the results|contributed to the graphical representation of data	designed the experiment	Conceived and designed the experiments	Methodology	YES
5744081	29312426	MM	2	designed the experiment|performed the experiments and experimental measures|analyzed and interpreted all the results|contributed to the graphical representation of data	performed the experiments and experimental measures	Performed the experiments	Investigation	YES
5744081	29312426	MM	2	designed the experiment|performed the experiments and experimental measures|analyzed and interpreted all the results|contributed to the graphical representation of data	analyzed and interpreted all the results	Analyzed the data	Formal analysis	YES
5744081	29312426	MM	2	designed the experiment|performed the experiments and experimental measures|analyzed and interpreted all the results|contributed to the graphical representation of data	contributed to the graphical representation of data	Contributed reagents/materials/analysis tools	Resources	YES
5744081	29312426	NM	2	analyzed and interpreted all the results|commented critically on the manuscript	analyzed and interpreted all the results	Analyzed the data	Formal analysis	YES
5744081	29312426	NM	2	analyzed and interpreted all the results|commented critically on the manuscript	commented critically on the manuscript	-	-	NO
5218955	28063147	All	2	sequences used in this study is available in the dna databank of japan|other data are available on request	sequences used in this study is available in the dna databank of japan	Performed the experiments	Investigation	YES
5218955	28063147	All	2	sequences used in this study is available in the dna databank of japan|other data are available on request	other data are available on request	-	-	NO
5218955	28063147	All authors	2	contributed equally in the write up of this article|read and approved the final manuscript	contributed equally in the write up of this article	Wrote the paper	Writing - Original Draft	YES
5218955	28063147	All authors	2	contributed equally in the write up of this article|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5218955	28063147	See Additional	2	file 1 for details	file 1 for details	-	-	NO
5218955	28063147	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
4194125	24837709	AW	PLoS52	analysed data	analysed data	Analyzed the data	Formal analysis	YES
4194125	24837709	BM	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
4194125	24837709	CF	PLoS52	contributed analytical tools/reagents|wrote the paper	contributed analytical tools/reagents	Contributed reagents/materials/analysis tools	Resources	YES
4194125	24837709	CF	PLoS52	contributed analytical tools/reagents|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4194125	24837709	CM	PLoS52	analysed data	analysed data	Analyzed the data	Formal analysis	YES
4194125	24837709	DEN	PLoS52	designed research|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
4194125	24837709	DEN	PLoS52	designed research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4194125	24837709	EG	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
4194125	24837709	HI-Z	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
4194125	24837709	HS	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
4194125	24837709	IGM	PLoS52	designed research|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
4194125	24837709	IGM	PLoS52	designed research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4194125	24837709	JB	PLoS52	performed research|performed research	performed research	Performed the experiments	Investigation	YES
4194125	24837709	JB	PLoS52	performed research|performed research	performed research	Performed the experiments	Investigation	YES
4194125	24837709	JG	PLoS52	contributed analytical tools/reagents	contributed analytical tools/reagents	Contributed reagents/materials/analysis tools	Resources	YES
4194125	24837709	KB	PLoS52	contributed analytical tools/reagents	contributed analytical tools/reagents	Contributed reagents/materials/analysis tools	Resources	YES
4194125	24837709	MA	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
4194125	24837709	NP-G	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
4194125	24837709	RR	PLoS52	performed research|analysed data	performed research	Performed the experiments	Investigation	YES
4194125	24837709	RR	PLoS52	performed research|analysed data	analysed data	Analyzed the data	Formal analysis	YES
4194125	24837709	RS	PLoS52	analysed data	analysed data	Analyzed the data	Formal analysis	YES
4194125	24837709	VZ	PLoS52	designed research|performed research|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
4194125	24837709	VZ	PLoS52	designed research|performed research|wrote the paper	performed research	Performed the experiments	Investigation	YES
4194125	24837709	VZ	PLoS52	designed research|performed research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
1930153	17668051	BC	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1930153	17668051	BC	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1930153	17668051	CL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1930153	17668051	CV	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1930153	17668051	PS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1930153	17668051	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1930153	17668051	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1930153	17668051	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1930153	17668051	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415775	25928805	KK	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4415775	25928805	KK	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4415775	25928805	MK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4415775	25928805	NK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4415775	25928805	TA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415775	25928805	TA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415775	25928805	TA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415775	25928805	TA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415775	25928805	TA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415775	25928805	TI	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415775	25928805	TI	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415775	25928805	TI	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415775	25928805	TO	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5222764	28070827	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5222764	28070827	BS	2	designed experiments and wrote the manuscript	designed experiments and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5222764	28070827	CW	2	designed experiments and wrote the manuscript	designed experiments and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5222764	28070827	CZ	2	performed experiments, and analyzed data|conceived of the study|designed experiments and wrote the manuscript	performed experiments, and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5222764	28070827	CZ	2	performed experiments, and analyzed data|conceived of the study|designed experiments and wrote the manuscript	conceived of the study	Conceived and designed the experiments	Conceptualization	YES
5222764	28070827	CZ	2	performed experiments, and analyzed data|conceived of the study|designed experiments and wrote the manuscript	designed experiments and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5222764	28070827	Detection System	2	version with 3	version with 3	-	-	NO
5222764	28070827	JL	2	performed experiments, and analyzed data|conceived of the study	performed experiments, and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5222764	28070827	JL	2	performed experiments, and analyzed data|conceived of the study	conceived of the study	Conceived and designed the experiments	Conceptualization	YES
5222764	28070827	LY	2	performed experiments, and analyzed data	performed experiments, and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5222764	28070827	PCR	2	version with 3	version with 3	-	-	NO
5222764	28070827	SC	2	performed experiments, and analyzed data	performed experiments, and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5222764	28070827	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5657082	29513193	FM	2	implemented and tested them and was a major contributor in raw data preparations including the dedicated location ontologies	implemented and tested them and was a major contributor in raw data preparations including the dedicated location ontologies	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5657082	29513193	FZ	2	proposed the tree and rule learning methods|wrote the manuscript	proposed the tree and rule learning methods	Conceived and designed the experiments|Performed the experiments	Conceptualization	YES
5657082	29513193	FZ	2	proposed the tree and rule learning methods|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5657082	29513193	JK	2	proposed, implemented and tested the bidirectional enrichment method|wrote the manuscript	proposed, implemented and tested the bidirectional enrichment method	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5657082	29513193	JK	2	proposed, implemented and tested the bidirectional enrichment method|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4619824	26539504	Achim G. Beule	2	contributed to development of wound model and revision of paper	contributed to development of wound model and revision of paper	Performed the experiments|Wrote the paper	Methodology|Writing - Original Draft|Writing - Review & Editing	YES
4619824	26539504	Christian Scharf	2	contributed to design of study and experimental planning, data analysis, conception, drafting and revision of paper, and acquisition of funds	contributed to design of study and experimental planning, data analysis, conception, drafting and revision of paper, and acquisition of funds	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Funding acquisition|Investigation|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
4619824	26539504	Christine Eymann	2	contributed to interpretation of the data and writing of paper	contributed to interpretation of the data and writing of paper	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
4619824	26539504	Derik Lendeckel	2	contributed to the analysis and interpretation of data and drafting the paper	contributed to the analysis and interpretation of data and drafting the paper	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
4619824	26539504	INPen	2	plasma source, acquisition of funding, and revision of paper|plasma source, acquisition of funding, and revision of paper	plasma source, acquisition of funding, and revision of paper	Performed the experiments|Wrote the paper	Funding acquisition|Investigation|Writing - Review & Editing	YES
4619824	26539504	INPen	2	plasma source, acquisition of funding, and revision of paper|plasma source, acquisition of funding, and revision of paper	plasma source, acquisition of funding, and revision of paper	Performed the experiments|Wrote the paper	Funding acquisition|Investigation|Writing - Review & Editing	YES
4619824	26539504	Katrin Darm	2	contributed to cell cultivation, plasma treatment, and dige experiment	contributed to cell cultivation, plasma treatment, and dige experiment	Performed the experiments	Investigation	YES
4619824	26539504	ONeil	2	contributed to data analysis and drafting of paper	contributed to data analysis and drafting of paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4619824	26539504	Philipp Emicke	2	contributed to gel image and mass spectrometry analyses, statistical analyses, and drafting of paper	contributed to gel image and mass spectrometry analyses, statistical analyses, and drafting of paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Visualization|Writing - Original Draft	YES
4619824	26539504	Uwe Volker	2	contributed to provision of mass spectrometry instruments and ipa data analysis software	contributed to provision of mass spectrometry instruments and ipa data analysis software	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources|Software	YES
4619824	26539504	Werner Hosemann	2	contributed to acquisition of funding and revision of paper	contributed to acquisition of funding and revision of paper	Wrote the paper	Funding acquisition|Writing - Review & Editing	YES
5744184	29312417	All authors	2	participated in manuscript preparation	participated in manuscript preparation	Wrote the paper	Writing - Original Draft	YES
5744184	29312417	HR	2	performed experiments and designed the research	performed experiments and designed the research	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5744184	29312417	MI	2	performed experiments and designed the research	performed experiments and designed the research	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5744184	29312417	MP	2	was involved in the phylogenetic tree analysis	was involved in the phylogenetic tree analysis	Performed the experiments	Investigation	YES
5744184	29312417	NN	2	performed experiments and designed the research	performed experiments and designed the research	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5744184	29312417	SG-G	2	performed experiments and designed the research	performed experiments and designed the research	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6128370	30258563	CW	2	was responsible for cell maintenance	was responsible for cell maintenance	Performed the experiments	Investigation	YES
6128370	30258563	DG	2	was responsible for funding	was responsible for funding	-	Funding acquisition	YES
6128370	30258563	LJ	2	performed experiments, analysed data and prepared the manuscript	performed experiments, analysed data and prepared the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
1930154	17668069	DR	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1930154	17668069	DR	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1930154	17668069	HL	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1930154	17668069	LW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1930154	17668069	MW	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1930154	17668069	PM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1930154	17668069	RC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1930154	17668069	RC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1930154	17668069	RC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1930154	17668069	RC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1930154	17668069	SB	PLoS5	Contributed reagents/materials/analysis tools|Principal investigator	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1930154	17668069	SB	PLoS5	Contributed reagents/materials/analysis tools|Principal investigator	Principal investigator	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
4415778	25927360	ARS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4415778	25927360	ARS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4415778	25927360	ARS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415778	25927360	BS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4415778	25927360	BS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415778	25927360	CEC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415778	25927360	CEC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415778	25927360	CEC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415778	25927360	DH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4415778	25927360	DH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4415778	25927360	DH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415778	25927360	GG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4415778	25927360	GP	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4415778	25927360	GP	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4415778	25927360	GP	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415778	25927360	KM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415778	25927360	KS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415778	25927360	KS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415778	25927360	KS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415778	25927360	NI	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415778	25927360	NI	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4415778	25927360	OL	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415778	25927360	OL	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4415778	25927360	PKG	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4415778	25927360	PKG	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4415778	25927360	PKG	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415778	25927360	PM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415778	25927360	PM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4415778	25927360	PM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4415778	25927360	PS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4415778	25927360	RB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4415778	25927360	RB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4415778	25927360	RB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415778	25927360	S. Mazumdar	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415778	25927360	S. Mehta	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415778	25927360	S. Mehta	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415778	25927360	S. Mehta	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415778	25927360	SD	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4415778	25927360	SD	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4415778	25927360	SK	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4415778	25927360	SK	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415778	25927360	SM	PLoS5	Performed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4415778	25927360	SM	PLoS5	Performed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4415778	25927360	SSY	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4415778	25927360	SSY	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4415778	25927360	SSY	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415778	25927360	VP	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4415778	25927360	VS	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415778	25927360	VSC	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415778	25927360	VSC	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4195764	24952894	APJ	2	the chemistry	the chemistry	-	-	NO
4195764	24952894	All authors	2	discussed the results and commented on the manuscript	discussed the results and commented on the manuscript	-	-	NO
4195764	24952894	CWGF	2	the chemistry	the chemistry	-	-	NO
4195764	24952894	JL	2	helped kjs with	helped kjs with	-	-	NO
4195764	24952894	PJFH	2	aiding interpretation	aiding interpretation	Analyzed the data	Formal analysis	YES
4619827	26539499	Johannes Knobloch	2	contributed equally	contributed equally	-	-	NO
4619827	26539499	Martin Nitschke	2	contributed equally	contributed equally	-	-	NO
5744193	29312421	All of the authors	2	have read and approved the final version of the manuscript	have read and approved the final version of the manuscript	-	-	NO
5241254	28097594	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5241254	28097594	EWL	2	assisted nmr data analysis	assisted nmr data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5241254	28097594	LLM	2	conceived this study	conceived this study	Conceived and designed the experiments	Conceptualization	YES
5241254	28097594	TTH	2	isolated vibrio strains used in this work	isolated vibrio strains used in this work	Performed the experiments	Investigation	YES
5241254	28097594	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5241254	28097594	XYG	2	performed the experiments, analyzed the data as well as results and wrote the manuscript	performed the experiments, analyzed the data as well as results and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5241254	28097594	YL	2	conceived this study	conceived this study	Conceived and designed the experiments	Conceptualization	YES
5241254	28097594	ZPL	2	conceived this study|supervised all the experiments and revised the manuscript	conceived this study	Conceived and designed the experiments	Conceptualization	YES
5241254	28097594	ZPL	2	conceived this study|supervised all the experiments and revised the manuscript	supervised all the experiments and revised the manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
1930155	17668059	HB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1930155	17668059	HB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1930155	17668059	HB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1930155	17668059	NY	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1930155	17668059	NY	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1930155	17668059	NY	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1930155	17668059	YY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1930155	17668059	YY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1930155	17668059	YY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1930155	17668059	YY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1930155	17668059	YY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5657092	29513192	JJT	2	participated in providing ideas and improving the manuscript	participated in providing ideas and improving the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5657092	29513192	LYW	2	participated in designing the experiments, drafting the manuscript and performing the statistical analysis	participated in designing the experiments, drafting the manuscript and performing the statistical analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5657092	29513192	QZ	2	participated in providing ideas and improving the manuscript	participated in providing ideas and improving the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5744400	29312406	All authors	PLoS52	contributed to experimental design and interpretation	contributed to experimental design and interpretation	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5744400	29312406	HT	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5744400	29312406	LT	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5744400	29312406	LW	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5744400	29312406	MW	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5744400	29312406	RL-D	PLoS52	conceived the project and wrote the manuscript with contributions from all authors	conceived the project and wrote the manuscript with contributions from all authors	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5744400	29312406	TJ-G	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
4415779	25927833	CMB	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415779	25927833	DLK	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415779	25927833	LF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415779	25927833	LF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415779	25927833	LF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415779	25927833	LF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415779	25927833	MCGC	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415779	25927833	MCGC	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415779	25927833	MTC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415779	25927833	MTC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415779	25927833	MTC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415779	25927833	PDG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415779	25927833	PDG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415779	25927833	PDG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415779	25927833	PDG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4195770	25063673	CK	2	provided reagents and support in analysing the data	provided reagents and support in analysing the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
4195770	25063673	DTO	2	provided reagents and support in analysing the data	provided reagents and support in analysing the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
4195770	25063673	HF	2	characterised the mouse model and performed behavioural tests	characterised the mouse model and performed behavioural tests	Performed the experiments	Investigation|Methodology	YES
4195770	25063673	JGG	2	provided reagents and support in analysing the data	provided reagents and support in analysing the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
4195770	25063673	JU	2	provided reagents and support in analysing the data	provided reagents and support in analysing the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
4195770	25063673	JVF	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
4195770	25063673	LB	2	characterised the mouse model and performed behavioural tests	characterised the mouse model and performed behavioural tests	Performed the experiments	Investigation|Methodology	YES
4195770	25063673	LG	2	characterised the mouse model and performed behavioural tests	characterised the mouse model and performed behavioural tests	Performed the experiments	Investigation|Methodology	YES
4195770	25063673	LT	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
4195770	25063673	MF	2	conceived the general framework of this study|prepared the manuscript	conceived the general framework of this study	Conceived and designed the experiments	Conceptualization	YES
4195770	25063673	MF	2	conceived the general framework of this study|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
4195770	25063673	MH	2	provided reagents and support in analysing the data	provided reagents and support in analysing the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
4195770	25063673	MHdA	2	characterised the mouse model and performed behavioural tests	characterised the mouse model and performed behavioural tests	Performed the experiments	Investigation|Methodology	YES
4195770	25063673	ML	2	provided reagents and support in analysing the data	provided reagents and support in analysing the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
4195770	25063673	MP	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
4195770	25063673	PH	2	provided reagents and support in analysing the data	provided reagents and support in analysing the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
4195770	25063673	PL	2	performed bioinformatics analyses	performed bioinformatics analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4195770	25063673	RTK	2	provided reagents and support in analysing the data	provided reagents and support in analysing the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
4195770	25063673	SB	2	conceived the general framework of this study|designed and performed experiments|prepared the manuscript	conceived the general framework of this study	Conceived and designed the experiments	Conceptualization	YES
4195770	25063673	SB	2	conceived the general framework of this study|designed and performed experiments|prepared the manuscript	designed and performed experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4195770	25063673	SB	2	conceived the general framework of this study|designed and performed experiments|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
4195770	25063673	SD	2	performed bioinformatics analyses	performed bioinformatics analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4195770	25063673	SH	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
4195770	25063673	SK	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
4195770	25063673	SMH	2	characterised the mouse model and performed behavioural tests	characterised the mouse model and performed behavioural tests	Performed the experiments	Investigation|Methodology	YES
4195770	25063673	TK	2	characterised the mouse model and performed behavioural tests	characterised the mouse model and performed behavioural tests	Performed the experiments	Investigation|Methodology	YES
4195770	25063673	VG-D	2	characterised the mouse model and performed behavioural tests	characterised the mouse model and performed behavioural tests	Performed the experiments	Investigation|Methodology	YES
4195770	25063673	WW	2	characterised the mouse model and performed behavioural tests	characterised the mouse model and performed behavioural tests	Performed the experiments	Investigation|Methodology	YES
5256623	28116697	All	2	data is shown in graphs, figures and table	data is shown in graphs, figures and table	-	Visualization	YES
5256623	28116697	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5256623	28116697	GC	2	planned and carried out the experiments, analyzed the data and wrote the manuscript	planned and carried out the experiments, analyzed the data and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
5256623	28116697	KS	2	assisted to carry out experiments	assisted to carry out experiments	Performed the experiments	Investigation	YES
5256623	28116697	QB	2	assisted to carry out experiments	assisted to carry out experiments	Performed the experiments	Investigation	YES
5256623	28116697	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5256623	28116697	XFT	2	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5256623	28116697	ZQW	2	participated in the data analysis and finalized the manuscript	participated in the data analysis and finalized the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
3696339	23560809	HM	2	supervised lgd during analysis and interpretation of the spirometry results	supervised lgd during analysis and interpretation of the spirometry results	Analyzed the data	Formal analysis|Supervision	YES
3696339	23560809	JS	2	supervised the project from planning to the preparation of the final manuscript	supervised the project from planning to the preparation of the final manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
3696339	23560809	LGD	2	planned and directed this trial and is responsible for data analysis and preparation of the initial manuscript	planned and directed this trial and is responsible for data analysis and preparation of the initial manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Supervision|Writing - Original Draft	YES
1930156	17668064	BR	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1930156	17668064	BR	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1930156	17668064	DP	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1930156	17668064	DP	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1930156	17668064	KS	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1930156	17668064	KS	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1930156	17668064	KS	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1930156	17668064	MT	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1930156	17668064	MT	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1930156	17668064	MT	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1930156	17668064	RC	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1930156	17668064	RC	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1930156	17668064	RG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1930156	17668064	RG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1930156	17668064	RG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1930156	17668064	YJ	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5657101	29070035	DL	2	normalized expression data, generated and compiled signatures, and designed and developed savant	normalized expression data, generated and compiled signatures, and designed and developed savant	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5657101	29070035	DM	2	conceived the project and analyses	conceived the project and analyses	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
5657101	29070035	MA	2	normalized expression data, generated and compiled signatures, and designed and developed savant	normalized expression data, generated and compiled signatures, and designed and developed savant	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5657101	29070035	MP	2	conceived the project and analyses	conceived the project and analyses	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
5657101	29070035	RM	2	conceived the project and analyses	conceived the project and analyses	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
5657101	29070035	VanT	2	during development	during development	-	-	NO
4415780	25928631	BHMM	PLoS5	Contributed reagents/materials/analysis tools|Performed the structure modeling	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415780	25928631	BHMM	PLoS5	Contributed reagents/materials/analysis tools|Performed the structure modeling	Performed the structure modeling	Performed the experiments	Investigation|Methodology	YES
4415780	25928631	BRM	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4415780	25928631	BRM	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4415780	25928631	JC-R	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415780	25928631	JC-R	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415780	25928631	JC-R	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415780	25928631	VK	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4415780	25928631	VK	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5744402	29312420	All authors	2	have read and approved the final version of the manuscript	have read and approved the final version of the manuscript	-	-	NO
4198050	24843046	PCK	2	designed and led the study and wrote the manuscript	designed and led the study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5256632	28116698	Both authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5256632	28116698	DP	2	developed hypothesis, supervised the work on bench and helped prepare the manuscript	developed hypothesis, supervised the work on bench and helped prepare the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Supervision|Writing - Original Draft	YES
5256632	28116698	Hanna Koch	2	et al	et al	-	-	NO
5256632	28116698	Holger Daims	2	et al	et al	-	-	NO
5256632	28116698	QY	2	designed and worked on bench as well as drafted the manuscript	designed and worked on bench as well as drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Writing - Original Draft	YES
5256632	28116698	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5744437	29312424	DC	1	Experiments	Experiments	-	-	NO
5744437	29312424	JL	1	Experiments	Experiments	-	-	NO
5744437	29312424	LZ	1	Experiments	Experiments	-	-	NO
5744437	29312424	MY	1	Data analysis	Data analysis	Analyzed the data	Formal analysis	YES
5744437	29312424	PL	1	Experiments	Experiments	-	-	NO
5744437	29312424	TX	1	Experiments	Experiments	-	-	NO
5744437	29312424	XL	1	Experimental design|Manuscript preparation|Supervision, funding and reagents	Experimental design	Conceived and designed the experiments	Methodology	YES
5744437	29312424	XL	1	Experimental design|Manuscript preparation|Supervision, funding and reagents	Manuscript preparation	Wrote the paper	Writing - Original Draft	YES
5744437	29312424	XL	1	Experimental design|Manuscript preparation|Supervision, funding and reagents	Supervision, funding and reagents	-	Funding acquisition|Supervision	YES
5744437	29312424	YY	1	Experimental design|Experiments|Data analysis|Manuscript preparation	Experimental design	Conceived and designed the experiments	Methodology	YES
5744437	29312424	YY	1	Experimental design|Experiments|Data analysis|Manuscript preparation	Experiments	-	-	NO
5744437	29312424	YY	1	Experimental design|Experiments|Data analysis|Manuscript preparation	Data analysis	Analyzed the data	Formal analysis	YES
5744437	29312424	YY	1	Experimental design|Experiments|Data analysis|Manuscript preparation	Manuscript preparation	Wrote the paper	Writing - Original Draft	YES
4232046	25092765	AAB	2	mk experimental design|interpretation of generated data|writing the manuscript	mk experimental design	Conceived and designed the experiments	Methodology	YES
4232046	25092765	AAB	2	mk experimental design|interpretation of generated data|writing the manuscript	interpretation of generated data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4232046	25092765	AAB	2	mk experimental design|interpretation of generated data|writing the manuscript	writing the manuscript	Wrote the paper	Writing - Original Draft	YES
4232046	25092765	AAV	2	kt experiments	kt experiments	-	-	NO
4232046	25092765	BEL	2	kt experiments	kt experiments	-	-	NO
4232046	25092765	DC	2	mk experimental design	mk experimental design	Conceived and designed the experiments	Methodology	YES
4232046	25092765	ERW	2	kt experiments	kt experiments	-	-	NO
4232046	25092765	FG	2	mk experimental design|kt experiments|interpretation of generated data|writing the manuscript	mk experimental design	Conceived and designed the experiments	Methodology	YES
4232046	25092765	FG	2	mk experimental design|kt experiments|interpretation of generated data|writing the manuscript	kt experiments	-	-	NO
4232046	25092765	FG	2	mk experimental design|kt experiments|interpretation of generated data|writing the manuscript	interpretation of generated data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4232046	25092765	FG	2	mk experimental design|kt experiments|interpretation of generated data|writing the manuscript	writing the manuscript	Wrote the paper	Writing - Original Draft	YES
4232046	25092765	HH	2	mk experimental design|interpretation of generated data|writing the manuscript	mk experimental design	Conceived and designed the experiments	Methodology	YES
4232046	25092765	HH	2	mk experimental design|interpretation of generated data|writing the manuscript	interpretation of generated data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4232046	25092765	HH	2	mk experimental design|interpretation of generated data|writing the manuscript	writing the manuscript	Wrote the paper	Writing - Original Draft	YES
4232046	25092765	NR	2	kt experiments	kt experiments	-	-	NO
4232046	25092765	PH	2	mk experimental design|kt experiments|interpretation of generated data|writing the manuscript	mk experimental design	Conceived and designed the experiments	Methodology	YES
4232046	25092765	PH	2	mk experimental design|kt experiments|interpretation of generated data|writing the manuscript	kt experiments	-	-	NO
4232046	25092765	PH	2	mk experimental design|kt experiments|interpretation of generated data|writing the manuscript	interpretation of generated data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4232046	25092765	PH	2	mk experimental design|kt experiments|interpretation of generated data|writing the manuscript	writing the manuscript	Wrote the paper	Writing - Original Draft	YES
4232046	25092765	RAC	2	mk experimental design	mk experimental design	Conceived and designed the experiments	Methodology	YES
4232046	25092765	SRB	2	kt experiments	kt experiments	-	-	NO
4232046	25092765	UM	2	mk experimental design	mk experimental design	Conceived and designed the experiments	Methodology	YES
4232046	25092765	VK	2	kt experiments	kt experiments	-	-	NO
5657102	29513197	JYW	2	conducted this research|applied the simulation experiments|wrote this manuscript	conducted this research	Performed the experiments	Investigation	YES
5657102	29513197	JYW	2	conducted this research|applied the simulation experiments|wrote this manuscript	applied the simulation experiments	-	Formal analysis	YES
5657102	29513197	JYW	2	conducted this research|applied the simulation experiments|wrote this manuscript	wrote this manuscript	Wrote the paper	Writing - Original Draft	YES
5657102	29513197	KY	2	applied the experiments on tcga dataset	applied the experiments on tcga dataset	-	-	NO
5657102	29513197	WKW	2	designed the algorithm|applied the simulation experiments|wrote this manuscript	designed the algorithm	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
5657102	29513197	WKW	2	designed the algorithm|applied the simulation experiments|wrote this manuscript	applied the simulation experiments	-	Formal analysis	YES
5657102	29513197	WKW	2	designed the algorithm|applied the simulation experiments|wrote this manuscript	wrote this manuscript	Wrote the paper	Writing - Original Draft	YES
5657102	29513197	XJC	2	applied the simulation experiments	applied the simulation experiments	-	Formal analysis	YES
5657102	29513197	XPZ	2	designed the algorithm	designed the algorithm	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
5657102	29513197	XX	2	wrote this manuscript	wrote this manuscript	Wrote the paper	Writing - Original Draft	YES
5657102	29513197	YG	2	designed the algorithm|applied the simulation experiments|applied the experiments on tcga dataset	designed the algorithm	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
5657102	29513197	YG	2	designed the algorithm|applied the simulation experiments|applied the experiments on tcga dataset	applied the simulation experiments	-	Formal analysis	YES
5657102	29513197	YG	2	designed the algorithm|applied the simulation experiments|applied the experiments on tcga dataset	applied the experiments on tcga dataset	-	-	NO
5657102	29513197	ZMZ	2	conducted this research	conducted this research	Performed the experiments	Investigation	YES
1931610	17668074	FS	PLoS5	Performed the experiments|Analyzed the data|Provided critical comments and provided materials for the paper	Performed the experiments	Performed the experiments	Investigation	YES
1931610	17668074	FS	PLoS5	Performed the experiments|Analyzed the data|Provided critical comments and provided materials for the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1931610	17668074	FS	PLoS5	Performed the experiments|Analyzed the data|Provided critical comments and provided materials for the paper	Provided critical comments and provided materials for the paper	Contributed reagents/materials/analysis tools	Resources	YES
1931610	17668074	LC	PLoS5	Performed the experiments|Provided critical comments and provided materials for the paper	Performed the experiments	Performed the experiments	Investigation	YES
1931610	17668074	LC	PLoS5	Performed the experiments|Provided critical comments and provided materials for the paper	Provided critical comments and provided materials for the paper	Contributed reagents/materials/analysis tools	Resources	YES
1931610	17668074	ML	PLoS5	Performed the experiments|Analyzed the data|Helped in designing the experiments|Provided critical comments and provided materials for the paper	Performed the experiments	Performed the experiments	Investigation	YES
1931610	17668074	ML	PLoS5	Performed the experiments|Analyzed the data|Helped in designing the experiments|Provided critical comments and provided materials for the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1931610	17668074	ML	PLoS5	Performed the experiments|Analyzed the data|Helped in designing the experiments|Provided critical comments and provided materials for the paper	Helped in designing the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
1931610	17668074	ML	PLoS5	Performed the experiments|Analyzed the data|Helped in designing the experiments|Provided critical comments and provided materials for the paper	Provided critical comments and provided materials for the paper	Contributed reagents/materials/analysis tools	Resources	YES
1931610	17668074	SA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1931610	17668074	SA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1931610	17668074	SA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415781	25928635	BL	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415781	25928635	BL	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415781	25928635	BY	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4415781	25928635	CL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415781	25928635	HL	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415781	25928635	HL	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415781	25928635	HL	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415781	25928635	JL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4415781	25928635	JZ	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4415781	25928635	LS	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4415781	25928635	MY	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415781	25928635	ZZ	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5744440	29312425	JC	2	contributed in revising manuscript	contributed in revising manuscript	Wrote the paper	Writing - Review & Editing	YES
5744440	29312425	JM	2	contributed in revising manuscript	contributed in revising manuscript	Wrote the paper	Writing - Review & Editing	YES
5744440	29312425	W-wL	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5744440	29312425	Y-sL	2	contributed in revising manuscript	contributed in revising manuscript	Wrote the paper	Writing - Review & Editing	YES
5265227	28116699	AER	PLoS52	performed the experiments|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5265227	28116699	AER	PLoS52	performed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5265227	28116699	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5265227	28116699	DAMP	PLoS52	performed the experiments|analysed data	performed the experiments	Performed the experiments	Investigation	YES
5265227	28116699	DAMP	PLoS52	performed the experiments|analysed data	analysed data	Analyzed the data	Formal analysis	YES
5265227	28116699	MAP	PLoS52	conceived the idea and designed the experiments	conceived the idea and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5265227	28116699	MM	PLoS52	analysed data	analysed data	Analyzed the data	Formal analysis	YES
1931611	17684549	AS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1931611	17684549	CK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1931611	17684549	CK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1931611	17684549	CK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1931611	17684549	CK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1931611	17684549	GB	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1931611	17684549	GC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1931611	17684549	GC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415782	25928544	GS	PLoS5	Contributed to the discussion and reviewed the manuscript	Contributed to the discussion and reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
4415782	25928544	IM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed to the discussion and reviewed the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415782	25928544	IM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed to the discussion and reviewed the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4415782	25928544	IM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed to the discussion and reviewed the manuscript	Contributed to the discussion and reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
4415782	25928544	JDR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed to the discussion and reviewed the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415782	25928544	JDR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed to the discussion and reviewed the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4415782	25928544	JDR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed to the discussion and reviewed the manuscript	Contributed to the discussion and reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
4415782	25928544	KM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Contributed to the discussion and reviewed the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415782	25928544	KM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Contributed to the discussion and reviewed the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4415782	25928544	KM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Contributed to the discussion and reviewed the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4415782	25928544	KM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Contributed to the discussion and reviewed the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415782	25928544	KM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Contributed to the discussion and reviewed the manuscript	Contributed to the discussion and reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
4282369	25260751	EG	2	conceived aspects of the experimental design, performed experiments, interpreted the data and wrote the manuscript	conceived aspects of the experimental design, performed experiments, interpreted the data and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4282369	25260751	MK	2	conceived aspects of the experimental design, performed experiments, interpreted the data and wrote the manuscript	conceived aspects of the experimental design, performed experiments, interpreted the data and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4282369	25260751	NC	2	conceived aspects of the experimental design, performed experiments, interpreted the data and wrote the manuscript	conceived aspects of the experimental design, performed experiments, interpreted the data and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4282369	25260751	SA	2	conceived aspects of the experimental design, performed experiments, interpreted the data and wrote the manuscript	conceived aspects of the experimental design, performed experiments, interpreted the data and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4282369	25260751	TS	2	conceived aspects of the experimental design, performed experiments, interpreted the data and wrote the manuscript	conceived aspects of the experimental design, performed experiments, interpreted the data and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4282369	25260751	XW	2	conceived aspects of the experimental design, performed experiments, interpreted the data and wrote the manuscript	conceived aspects of the experimental design, performed experiments, interpreted the data and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5658907	29078746	JLX	2	designed the experiment	designed the experiment	Conceived and designed the experiments	Methodology	YES
5658907	29078746	JZ	2	performed phenotypic evaluation|performed analysis and interpretation of the data|drafted the manuscript	performed phenotypic evaluation	Performed the experiments	Investigation	YES
5658907	29078746	JZ	2	performed phenotypic evaluation|performed analysis and interpretation of the data|drafted the manuscript	performed analysis and interpretation of the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5658907	29078746	JZ	2	performed phenotypic evaluation|performed analysis and interpretation of the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5658907	29078746	KC	2	performed phenotypic evaluation	performed phenotypic evaluation	Performed the experiments	Investigation	YES
5658907	29078746	LJX	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5658907	29078746	SAN	2	performed phenotypic evaluation	performed phenotypic evaluation	Performed the experiments	Investigation	YES
5658907	29078746	XQW	2	performed phenotypic evaluation	performed phenotypic evaluation	Performed the experiments	Investigation	YES
5658907	29078746	XQZ	2	performed phenotypic evaluation	performed phenotypic evaluation	Performed the experiments	Investigation	YES
5658907	29078746	YLP	2	performed analysis and interpretation of the data	performed analysis and interpretation of the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5658907	29078746	YW	2	performed phenotypic evaluation	performed phenotypic evaluation	Performed the experiments	Investigation	YES
5658907	29078746	ZKL	2	designed the experiment	designed the experiment	Conceived and designed the experiments	Methodology	YES
5744444	29312423	CL	2	provided the environmental data	provided the environmental data	Contributed reagents/materials/analysis tools	Resources	YES
5744444	29312423	LS	2	compiled the evi data|did the data analysis|wrote the first draft of the manuscript with contribution from others	compiled the evi data	-	Data curation	YES
5744444	29312423	LS	2	compiled the evi data|did the data analysis|wrote the first draft of the manuscript with contribution from others	did the data analysis	Analyzed the data	Formal analysis	YES
5744444	29312423	LS	2	compiled the evi data|did the data analysis|wrote the first draft of the manuscript with contribution from others	wrote the first draft of the manuscript with contribution from others	Wrote the paper	Writing - Original Draft	YES
5744444	29312423	LW	2	did the data analysis|wrote the first draft of the manuscript with contribution from others	did the data analysis	Analyzed the data	Formal analysis	YES
5744444	29312423	LW	2	did the data analysis|wrote the first draft of the manuscript with contribution from others	wrote the first draft of the manuscript with contribution from others	Wrote the paper	Writing - Original Draft	YES
5744444	29312423	YJ	2	provided the environmental data	provided the environmental data	Contributed reagents/materials/analysis tools	Resources	YES
5744444	29312423	YW	2	provided the environmental data	provided the environmental data	Contributed reagents/materials/analysis tools	Resources	YES
4619841	26539512	Abdulaziz Al Khulaifi	2	suggested the idea and, as a chair of the department, provided general support and substantial contribution to concept and design and acquisition of data	suggested the idea and, as a chair of the department, provided general support and substantial contribution to concept and design and acquisition of data	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceptualization|Investigation|Resources	YES
4619841	26539512	Alejandro Kohn Tuli	2	was responsible for data interpretation	was responsible for data interpretation	Analyzed the data	Formal analysis	YES
4619841	26539512	Amr S. Omar	2	carried out study design and contributed to concept, writing the paper, and revising the final form	carried out study design and contributed to concept, writing the paper, and revising the final form	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Writing - Original Draft	YES
4619841	26539512	Hany Osman	2	was responsible for data collection	was responsible for data collection	Performed the experiments	Investigation	YES
4619841	26539512	Praveen C. Sivadasan	2	was responsible for data management and paper revision	was responsible for data management and paper revision	Analyzed the data|Wrote the paper	Data curation|Writing - Review & Editing	YES
4619841	26539512	Rajvir Singh	2	conducted statistical analysis	conducted statistical analysis	Analyzed the data	Formal analysis	YES
4619841	26539512	Samy Hanoura	2	was responsible for data collection and paper revision	was responsible for data collection and paper revision	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4619841	26539512	Suraj Sudarsanan	2	was responsible for data collection, interpretation of data, and revising the paper	was responsible for data collection, interpretation of data, and revising the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
4619841	26539512	Yasser Shouman	2	was responsible for revision of the paper	was responsible for revision of the paper	Wrote the paper	Writing - Review & Editing	YES
1931612	17684552	JM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1931612	17684552	LG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1931612	17684552	LG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1931612	17684552	LG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1931612	17684552	PS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1931612	17684552	PS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1931612	17684552	PS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1931612	17684552	PS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1931612	17684552	SC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5267591	28124290	Both authors	2	read and approved the final manuscript|declare that they have no competing interests	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5267591	28124290	Both authors	2	read and approved the final manuscript|declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5267591	28124290	KL	2	designed research|performed research|analysed data and wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
5267591	28124290	KL	2	designed research|performed research|analysed data and wrote the paper	performed research	Performed the experiments	Investigation	YES
5267591	28124290	KL	2	designed research|performed research|analysed data and wrote the paper	analysed data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5267591	28124290	Monica Navarro-Gonzalez	2	is thanked for suggestions and discussions on experiments	is thanked for suggestions and discussions on experiments	-	-	NO
5267591	28124290	UK	2	designed research|analysed data and wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
5267591	28124290	UK	2	designed research|analysed data and wrote the paper	analysed data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4282387	25190518	CP	2	designed and performed experiments and analysed the data	designed and performed experiments and analysed the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
4282387	25190518	DS	2	designed and performed experiments and analysed the data	designed and performed experiments and analysed the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
4282387	25190518	GG	2	designed and performed experiments and analysed the data	designed and performed experiments and analysed the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
4282387	25190518	JES	2	designed the experiments, analysed the data and wrote the manuscript	designed the experiments, analysed the data and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4282387	25190518	MNP	2	provided and analysed the replication timing and sns data	provided and analysed the replication timing and sns data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources|Validation	YES
4282387	25190518	PM	2	designed and performed the biophysical analysis of the g4 motifs	designed and performed the biophysical analysis of the g4 motifs	Conceived and designed the experiments|Performed the experiments	Investigation	YES
4282387	25190518	PS	2	designed and performed experiments and analysed the data	designed and performed experiments and analysed the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
4282387	25190518	SB	2	designed and performed the biophysical analysis of the g4 motifs	designed and performed the biophysical analysis of the g4 motifs	Conceived and designed the experiments|Performed the experiments	Investigation	YES
4415784	25928219	HY	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415784	25928219	HY	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4415784	25928219	HY	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415784	25928219	JZ	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415784	25928219	JZ	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415784	25928219	LQ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415784	25928219	LQ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415784	25928219	LQ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415784	25928219	LQ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415784	25928219	MHW	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415784	25928219	MHW	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415784	25928219	MHW	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415784	25928219	XJL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4415784	25928219	XYF	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415784	25928219	XYF	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415784	25928219	ZGW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5744461	29312422	AM	PLoS52	designed and performed the greenhouse and field experiments	designed and performed the greenhouse and field experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5744461	29312422	DD	PLoS52	conceived of and designed the study|wrote the paper	conceived of and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5744461	29312422	DD	PLoS52	conceived of and designed the study|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5744461	29312422	DR	PLoS52	conceived of and designed the study	conceived of and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5744461	29312422	JS	PLoS52	conceived of and designed the study	conceived of and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5744461	29312422	KG	PLoS52	conceived of and designed the study|wrote the paper	conceived of and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5744461	29312422	KG	PLoS52	conceived of and designed the study|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5744461	29312422	PG	PLoS52	designed and performed the greenhouse and field experiments	designed and performed the greenhouse and field experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5744461	29312422	RL	PLoS52	designed and performed the greenhouse and field experiments|wrote the paper	designed and performed the greenhouse and field experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5744461	29312422	RL	PLoS52	designed and performed the greenhouse and field experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
1931613	17668071	BS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1931613	17668071	BS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1931613	17668071	BS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1931613	17668071	BS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1931613	17668071	WJ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1931613	17668071	WJ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1931613	17668071	WJ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5658915	29078754	FS	PLoS52	conceived and designed the experiment|performed the experiment|analyzed the data|wrote the manuscript	conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5658915	29078754	FS	PLoS52	conceived and designed the experiment|performed the experiment|analyzed the data|wrote the manuscript	performed the experiment	Performed the experiments	Investigation	YES
5658915	29078754	FS	PLoS52	conceived and designed the experiment|performed the experiment|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5658915	29078754	FS	PLoS52	conceived and designed the experiment|performed the experiment|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5658915	29078754	GC	PLoS52	performed the experiment	performed the experiment	Performed the experiments	Investigation	YES
5658915	29078754	HM	PLoS52	conceived and designed the experiment|wrote the manuscript	conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5658915	29078754	HM	PLoS52	conceived and designed the experiment|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5658915	29078754	LY	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5658915	29078754	MJ	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5658915	29078754	MMT	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5658915	29078754	XM	PLoS52	performed the experiment	performed the experiment	Performed the experiments	Investigation	YES
5658915	29078754	ZD	PLoS52	conceived and designed the experiment	conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5658915	29078754	ZL	PLoS52	performed the experiment	performed the experiment	Performed the experiments	Investigation	YES
4282640	25378478	AFN	2	designed and carried out experiments	designed and carried out experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4282640	25378478	JJ	2	designed and carried out experiments and wrote the manuscript	designed and carried out experiments and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
4282640	25378478	JM	2	supervised the project and contributed to writing the manuscript	supervised the project and contributed to writing the manuscript	Wrote the paper	Supervision|Writing - Original Draft	YES
4282640	25378478	JP	2	contributed to experiments	contributed to experiments	Performed the experiments	Investigation	YES
4282640	25378478	KH	2	contributed to experiments	contributed to experiments	Performed the experiments	Investigation	YES
4282640	25378478	MB	2	supervised the b cell part of the project	supervised the b cell part of the project	Performed the experiments	Investigation|Supervision	YES
4282640	25378478	MM	2	designed experiments	designed experiments	Conceived and designed the experiments	Methodology	YES
4282640	25378478	TH	2	designed and carried out experiments and wrote the manuscript|designed the shrna cloning strategy	designed and carried out experiments and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
4282640	25378478	TH	2	designed and carried out experiments and wrote the manuscript|designed the shrna cloning strategy	designed the shrna cloning strategy	Conceived and designed the experiments|Performed the experiments	Investigation	YES
4282640	25378478	TK	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5270615	28124289	All	2	data are fully available without restriction	data are fully available without restriction	-	-	NO
5270615	28124289	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5270615	28124289	CC	2	conceived of the study, designed the experiments and helped to draft the manuscript	conceived of the study, designed the experiments and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
5270615	28124289	CYX	2	performed the modeling analysis	performed the modeling analysis	Performed the experiments	Investigation|Methodology	YES
5270615	28124289	CZ	2	performed the modeling analysis	performed the modeling analysis	Performed the experiments	Investigation|Methodology	YES
5270615	28124289	GQL	2	conceived of the study, designed the experiments and helped to draft the manuscript	conceived of the study, designed the experiments and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
5270615	28124289	HY	2	performed the experiments, created the graphs and drafted this manuscript	performed the experiments, created the graphs and drafted this manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5270615	28124289	JFZ	2	performed the modeling analysis	performed the modeling analysis	Performed the experiments	Investigation|Methodology	YES
5270615	28124289	RHZ	2	participated in the design of the study	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
5270615	28124289	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
4415785	25927701	BQW	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415785	25927701	BQW	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415785	25927701	BQW	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415785	25927701	CQY	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415785	25927701	HW	PLoS5	Contributed to the data collection and data quality control	Contributed to the data collection and data quality control	Performed the experiments	Data curation|Investigation|Validation	YES
4415785	25927701	JL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415785	25927701	LMC	PLoS5	Contributed to the data collection and data quality control	Contributed to the data collection and data quality control	Performed the experiments	Data curation|Investigation|Validation	YES
4415785	25927701	LML	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415785	25927701	SFW	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415785	25927701	WHC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415785	25927701	WJG	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4415785	25927701	WJG	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4415785	25927701	XPW	PLoS5	Contributed to the data collection and data quality control	Contributed to the data collection and data quality control	Performed the experiments	Data curation|Investigation|Validation	YES
4415785	25927701	ZCP	PLoS5	Contributed to the data collection and data quality control	Contributed to the data collection and data quality control	Performed the experiments	Data curation|Investigation|Validation	YES
1933252	17668065	KM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1933252	17668065	KM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1933252	17668065	KM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1933252	17668065	KM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1933252	17668065	PM	PLoS5	Conceived and designed the experiments|Wrote the first draft of the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1933252	17668065	PM	PLoS5	Conceived and designed the experiments|Wrote the first draft of the paper	Wrote the first draft of the paper	Wrote the paper	Writing - Original Draft	YES
1933252	17668065	TT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1933252	17668065	TT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1933252	17668065	TT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5660447	29078748	CS	PLoS52	conceived and designed the study|critically reviewed the manuscript for important intellectual content and revised the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5660447	29078748	CS	PLoS52	conceived and designed the study|critically reviewed the manuscript for important intellectual content and revised the manuscript	critically reviewed the manuscript for important intellectual content and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5660447	29078748	HH	PLoS52	conducted sample collection|performed the experiments|conducted the literature search, performed data extraction and analysis, and interpreted the results|critically reviewed the manuscript for important intellectual content and revised the manuscript	conducted sample collection	Performed the experiments	Investigation	YES
5660447	29078748	HH	PLoS52	conducted sample collection|performed the experiments|conducted the literature search, performed data extraction and analysis, and interpreted the results|critically reviewed the manuscript for important intellectual content and revised the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5660447	29078748	HH	PLoS52	conducted sample collection|performed the experiments|conducted the literature search, performed data extraction and analysis, and interpreted the results|critically reviewed the manuscript for important intellectual content and revised the manuscript	conducted the literature search, performed data extraction and analysis, and interpreted the results	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5660447	29078748	HH	PLoS52	conducted sample collection|performed the experiments|conducted the literature search, performed data extraction and analysis, and interpreted the results|critically reviewed the manuscript for important intellectual content and revised the manuscript	critically reviewed the manuscript for important intellectual content and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5660447	29078748	JY	PLoS52	conceived and designed the study|conducted the literature search, performed data extraction and analysis, and interpreted the results|drafted and wrote the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5660447	29078748	JY	PLoS52	conceived and designed the study|conducted the literature search, performed data extraction and analysis, and interpreted the results|drafted and wrote the manuscript	conducted the literature search, performed data extraction and analysis, and interpreted the results	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5660447	29078748	JY	PLoS52	conceived and designed the study|conducted the literature search, performed data extraction and analysis, and interpreted the results|drafted and wrote the manuscript	drafted and wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5660447	29078748	MA	PLoS52	conducted sample collection|performed the experiments|conducted the literature search, performed data extraction and analysis, and interpreted the results|critically reviewed the manuscript for important intellectual content and revised the manuscript	conducted sample collection	Performed the experiments	Investigation	YES
5660447	29078748	MA	PLoS52	conducted sample collection|performed the experiments|conducted the literature search, performed data extraction and analysis, and interpreted the results|critically reviewed the manuscript for important intellectual content and revised the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5660447	29078748	MA	PLoS52	conducted sample collection|performed the experiments|conducted the literature search, performed data extraction and analysis, and interpreted the results|critically reviewed the manuscript for important intellectual content and revised the manuscript	conducted the literature search, performed data extraction and analysis, and interpreted the results	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5660447	29078748	MA	PLoS52	conducted sample collection|performed the experiments|conducted the literature search, performed data extraction and analysis, and interpreted the results|critically reviewed the manuscript for important intellectual content and revised the manuscript	critically reviewed the manuscript for important intellectual content and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5660447	29078748	SK	PLoS52	conceived and designed the study|critically reviewed the manuscript for important intellectual content and revised the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5660447	29078748	SK	PLoS52	conceived and designed the study|critically reviewed the manuscript for important intellectual content and revised the manuscript	critically reviewed the manuscript for important intellectual content and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5660447	29078748	TT	PLoS52	conducted sample collection|performed the experiments|critically reviewed the manuscript for important intellectual content and revised the manuscript	conducted sample collection	Performed the experiments	Investigation	YES
5660447	29078748	TT	PLoS52	conducted sample collection|performed the experiments|critically reviewed the manuscript for important intellectual content and revised the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5660447	29078748	TT	PLoS52	conducted sample collection|performed the experiments|critically reviewed the manuscript for important intellectual content and revised the manuscript	critically reviewed the manuscript for important intellectual content and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5285291	28144889	AEM	PLoS52	conceived and designed the experiments|analysed the data|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5285291	28144889	AEM	PLoS52	conceived and designed the experiments|analysed the data|wrote the paper	analysed the data	Analyzed the data	Formal analysis	YES
5285291	28144889	AEM	PLoS52	conceived and designed the experiments|analysed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5285291	28144889	All authors	PLoS52	read and approved the final manuscript|declare that they have no competing interests	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5285291	28144889	All authors	PLoS52	read and approved the final manuscript|declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5285291	28144889	CA	PLoS52	analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
5285291	28144889	CAO	PLoS52	conceived and designed the experiments|performed the experiments|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5285291	28144889	CAO	PLoS52	conceived and designed the experiments|performed the experiments|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5285291	28144889	CAO	PLoS52	conceived and designed the experiments|performed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5285291	28144889	ESS	PLoS52	analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
5285291	28144889	JGS	PLoS52	performed the experiments|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5285291	28144889	JGS	PLoS52	performed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5285291	28144889	MFS	PLoS52	conceived and designed the experiments|analysed the data|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5285291	28144889	MFS	PLoS52	conceived and designed the experiments|analysed the data|wrote the paper	analysed the data	Analyzed the data	Formal analysis	YES
5285291	28144889	MFS	PLoS52	conceived and designed the experiments|analysed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5285291	28144889	RFBS	PLoS52	performed the experiments|analysed the data|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5285291	28144889	RFBS	PLoS52	performed the experiments|analysed the data|wrote the paper	analysed the data	Analyzed the data	Formal analysis	YES
5285291	28144889	RFBS	PLoS52	performed the experiments|analysed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5285291	28144889	SF	PLoS52	conceived and designed the experiments|analysed the data|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5285291	28144889	SF	PLoS52	conceived and designed the experiments|analysed the data|wrote the paper	analysed the data	Analyzed the data	Formal analysis	YES
5285291	28144889	SF	PLoS52	conceived and designed the experiments|analysed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415786	25927832	AD	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415786	25927832	AD	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415786	25927832	ANT	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4415786	25927832	ANT	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415786	25927832	BB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415786	25927832	BB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415786	25927832	BB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415786	25927832	BL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415786	25927832	BL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415786	25927832	BL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415786	25927832	BL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415786	25927832	BVDE	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415786	25927832	BVDE	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415786	25927832	BVDE	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415786	25927832	DE	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415786	25927832	DHL	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415786	25927832	DHL	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415786	25927832	FH	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415786	25927832	FH	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415786	25927832	IF	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415786	25927832	IF	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415786	25927832	IF	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415786	25927832	JA	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415786	25927832	JA	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415786	25927832	JD	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4415786	25927832	JLG	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4415786	25927832	PD	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415786	25927832	PD	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415786	25927832	PD	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415786	25927832	PD	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415786	25927832	PD	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415786	25927832	PG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415786	25927832	PG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415786	25927832	PG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415786	25927832	TH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415786	25927832	TH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415786	25927832	TH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415786	25927832	TH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4282642	25391662	AG	2	contributed to data in fig 6	contributed to data in fig 6	-	-	NO
4282642	25391662	CL	2	conceived the project, designed the experiments, and wrote the manuscript|produced data in figs 2 7 supplementary figs s4 and s5	conceived the project, designed the experiments, and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
4282642	25391662	CL	2	conceived the project, designed the experiments, and wrote the manuscript|produced data in figs 2 7 supplementary figs s4 and s5	produced data in figs 2 7 supplementary figs s4 and s5	Performed the experiments	Investigation	YES
4282642	25391662	CR	2	produced data in supplementary figs s1 and s2	produced data in supplementary figs s1 and s2	Performed the experiments	Investigation	YES
4282642	25391662	GW	2	contributed to data in fig 3	contributed to data in fig 3	-	-	NO
4282642	25391662	LP	2	made intellectual contributions to the design and analysis of the experiments and helped with the drafting of the manuscript	made intellectual contributions to the design and analysis of the experiments and helped with the drafting of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
4282642	25391662	LS	2	contributed to data in fig 3	contributed to data in fig 3	-	-	NO
4282642	25391662	PA	2	produced data in fig 8 supplementary figs s18 and s20	produced data in fig 8 supplementary figs s18 and s20	Performed the experiments	Investigation	YES
4282642	25391662	PG	2	did the bulk of the data processing and bioinformatics	did the bulk of the data processing and bioinformatics	Analyzed the data	Data curation|Formal analysis	YES
4282642	25391662	TB	2	made intellectual contributions to the design and analysis of the experiments and helped with the drafting of the manuscript	made intellectual contributions to the design and analysis of the experiments and helped with the drafting of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
4282642	25391662	TG	2	contributed to data in supplementary fig s20	contributed to data in supplementary fig s20	-	-	NO
4282642	25391662	TS	2	conceived the project, designed the experiments, and wrote the manuscript|produced data in figs 1 and 3 , 4 5 6 7 8 9 and most supplementary figures and contributed to bioinformatics analysis	conceived the project, designed the experiments, and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
4282642	25391662	TS	2	conceived the project, designed the experiments, and wrote the manuscript|produced data in figs 1 and 3 , 4 5 6 7 8 9 and most supplementary figures and contributed to bioinformatics analysis	produced data in figs 1 and 3 , 4 5 6 7 8 9 and most supplementary figures and contributed to bioinformatics analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
4282642	25391662	VD	2	contributed to data in fig 7	contributed to data in fig 7	-	-	NO
1933253	17668070	AM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1933253	17668070	MG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1933253	17668070	ML	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1933253	17668070	ML	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1933253	17668070	ML	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1933253	17668070	PK	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1933253	17668070	TE	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1933253	17668070	TE	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1933253	17668070	TE	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5744475	29312402	CS	2	provided the initial research design and obtained funding|contributed to the research and analysis design, and to the writing of this article	provided the initial research design and obtained funding	Conceived and designed the experiments	Funding acquisition	YES
5744475	29312402	CS	2	provided the initial research design and obtained funding|contributed to the research and analysis design, and to the writing of this article	contributed to the research and analysis design, and to the writing of this article	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
5744475	29312402	SN	2	performed all remaining experiments and bioinformatics analyses|contributed to the research and analysis design, and to the writing of this article	performed all remaining experiments and bioinformatics analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5744475	29312402	SN	2	performed all remaining experiments and bioinformatics analyses|contributed to the research and analysis design, and to the writing of this article	contributed to the research and analysis design, and to the writing of this article	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
5744475	29312402	TA	2	performed the tsa experiments for figure	performed the tsa experiments for figure	Performed the experiments	Investigation|Visualization	YES
4415788	25928293	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415788	25928293	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415788	25928293	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415788	25928293	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415788	25928293	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415788	25928293	HK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415788	25928293	HK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415788	25928293	HK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415788	25928293	NMZ	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415788	25928293	NMZ	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415788	25928293	SNS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415788	25928293	SNS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415788	25928293	SNS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5660452	29078745	AW	PLoS52	conducted the analyses|drafted and edited the manuscript	conducted the analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5660452	29078745	AW	PLoS52	conducted the analyses|drafted and edited the manuscript	drafted and edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5660452	29078745	CHL	PLoS52	conducted the analyses	conducted the analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5660452	29078745	LXS	PLoS52	constructed the libraries	constructed the libraries	Performed the experiments	Investigation	YES
5660452	29078745	LZH	PLoS52	conceived and designed the experiments|drafted and edited the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5660452	29078745	LZH	PLoS52	conceived and designed the experiments|drafted and edited the manuscript	drafted and edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5660452	29078745	MH	PLoS52	conceived and designed the experiments|conducted the analyses|drafted and edited the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5660452	29078745	MH	PLoS52	conceived and designed the experiments|conducted the analyses|drafted and edited the manuscript	conducted the analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5660452	29078745	MH	PLoS52	conceived and designed the experiments|conducted the analyses|drafted and edited the manuscript	drafted and edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5660452	29078745	NN	PLoS52	conceived and designed the experiments|drafted and edited the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5660452	29078745	NN	PLoS52	conceived and designed the experiments|drafted and edited the manuscript	drafted and edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5660452	29078745	PFS	PLoS52	constructed the libraries|drafted and edited the manuscript	constructed the libraries	Performed the experiments	Investigation	YES
5660452	29078745	PFS	PLoS52	constructed the libraries|drafted and edited the manuscript	drafted and edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5660452	29078745	PPKA	PLoS52	constructed the libraries	constructed the libraries	Performed the experiments	Investigation	YES
5660452	29078745	SGL	PLoS52	procured the samples	procured the samples	-	-	NO
5660452	29078745	SH	PLoS52	conducted the analyses|drafted and edited the manuscript	conducted the analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5660452	29078745	SH	PLoS52	conducted the analyses|drafted and edited the manuscript	drafted and edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5660452	29078745	SZH	PLoS52	constructed the libraries	constructed the libraries	Performed the experiments	Investigation	YES
5660452	29078745	WFB	PLoS52	conceived and designed the experiments|drafted and edited the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5660452	29078745	WFB	PLoS52	conceived and designed the experiments|drafted and edited the manuscript	drafted and edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5660452	29078745	YOZ	PLoS52	conducted the analyses|drafted and edited the manuscript	conducted the analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5660452	29078745	YOZ	PLoS52	conducted the analyses|drafted and edited the manuscript	drafted and edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
1933254	17668072	CW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1933254	17668072	CW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1933254	17668072	CW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1933254	17668072	CW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1933254	17668072	CW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1933254	17668072	DN	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1933254	17668072	DN	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1933254	17668072	DN	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1933254	17668072	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1933254	17668072	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1933254	17668072	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1933254	17668072	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1933254	17668072	MV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1933254	17668072	MV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1933254	17668072	MV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1933254	17668072	MV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1933254	17668072	RS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1933254	17668072	RS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1933254	17668072	UH	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1933254	17668072	UH	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1933254	17668072	UH	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415791	25928295	AUHA	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415791	25928295	IA	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415791	25928295	IA	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415791	25928295	MAB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4415791	25928295	MAN	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4415791	25928295	MAN	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4415791	25928295	SMAB	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415791	25928295	SMAB	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5289932	28155199	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5289932	28155199	MS	PLoS52	designed and supervised the study, and wrote the manuscript	designed and supervised the study, and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Original Draft	YES
5289932	28155199	SH	PLoS52	designed and supervised the study, and wrote the manuscript	designed and supervised the study, and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Original Draft	YES
5289932	28155199	SU	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5289932	28155199	TK	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5289932	28155199	YS	PLoS52	designed and performed the experiments, and wrote the manuscript	designed and performed the experiments, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
4283404	25180228	HTN	2	performed experiments|designed experiments, analyzed data, and wrote the paper	performed experiments	Performed the experiments	Investigation	YES
4283404	25180228	HTN	2	performed experiments|designed experiments, analyzed data, and wrote the paper	designed experiments, analyzed data, and wrote the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4283404	25180228	HX	2	performed experiments|performed the xenograft experiments	performed experiments	Performed the experiments	Investigation	YES
4283404	25180228	HX	2	performed experiments|performed the xenograft experiments	performed the xenograft experiments	Performed the experiments	Investigation	YES
4283404	25180228	PMV	2	designed experiments, analyzed data, and wrote the paper	designed experiments, analyzed data, and wrote the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4283404	25180228	QC	2	performed the xenograft experiments	performed the xenograft experiments	Performed the experiments	Investigation	YES
4283404	25180228	RZ	2	performed computational analysis of cancer data	performed computational analysis of cancer data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4283404	25180228	SMC	2	designed experiments, analyzed data, and wrote the paper	designed experiments, analyzed data, and wrote the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4283404	25180228	XH	2	designed experiments, analyzed data, and wrote the paper	designed experiments, analyzed data, and wrote the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4283404	25180228	ZH	2	performed computational analysis of cancer data	performed computational analysis of cancer data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5744479	29312427	GC	2	coordinated the review and he wrote many parts of the article	coordinated the review and he wrote many parts of the article	Wrote the paper	Project administration|Writing - Original Draft|Writing - Review & Editing	YES
5744479	29312427	LH	2	wrote part of the review dealing the effects of protein hydrolystes on microbiome and she contributed to improve the article	wrote part of the review dealing the effects of protein hydrolystes on microbiome and she contributed to improve the article	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5744479	29312427	MC	2	wrote part of the review dealing with germination and seedling growth and she contributed to improve the article	wrote part of the review dealing with germination and seedling growth and she contributed to improve the article	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5744479	29312427	MR	2	wrote part of the review dealing with the microbiome and he contributed to improve the article	wrote part of the review dealing with the microbiome and he contributed to improve the article	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5744479	29312427	PB	2	wrote part of the review dealing with protein hydrolysate effects on plant growth	wrote part of the review dealing with protein hydrolysate effects on plant growth	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5744479	29312427	RC	2	wrote part of the review dealing with chemical characteristics of protein hydrolysates	wrote part of the review dealing with chemical characteristics of protein hydrolysates	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5744479	29312427	YR	2	wrote many parts of the article especially those dealing with the effects of protein hydrolysates on yield and quality and he contributed to improve the article	wrote many parts of the article especially those dealing with the effects of protein hydrolysates on yield and quality and he contributed to improve the article	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5661916	29084515	JKZ	2	performed experiments and contributed to data analysis and validation	performed experiments and contributed to data analysis and validation	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Validation	YES
5661916	29084515	LPX	2	conceived, designed and initiated the project|helped to revise the manuscript	conceived, designed and initiated the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5661916	29084515	LPX	2	conceived, designed and initiated the project|helped to revise the manuscript	helped to revise the manuscript	Wrote the paper	Writing - Review & Editing	YES
5661916	29084515	XZ	2	performed experiments and contributed to data analysis and validation	performed experiments and contributed to data analysis and validation	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Validation	YES
5661916	29084515	YCS	2	performed experiments and contributed to data analysis and validation	performed experiments and contributed to data analysis and validation	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Validation	YES
5661916	29084515	YTY	2	conceived, designed and initiated the project|prepared materials|performed experiments and contributed to data analysis and validation|drafted the manuscript	conceived, designed and initiated the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5661916	29084515	YTY	2	conceived, designed and initiated the project|prepared materials|performed experiments and contributed to data analysis and validation|drafted the manuscript	prepared materials	Performed the experiments	Investigation	YES
5661916	29084515	YTY	2	conceived, designed and initiated the project|prepared materials|performed experiments and contributed to data analysis and validation|drafted the manuscript	performed experiments and contributed to data analysis and validation	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Validation	YES
5661916	29084515	YTY	2	conceived, designed and initiated the project|prepared materials|performed experiments and contributed to data analysis and validation|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5661916	29084515	YXQ	2	conceived, designed and initiated the project|helped to revise the manuscript	conceived, designed and initiated the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5661916	29084515	YXQ	2	conceived, designed and initiated the project|helped to revise the manuscript	helped to revise the manuscript	Wrote the paper	Writing - Review & Editing	YES
5661916	29084515	ZTW	2	performed experiments and contributed to data analysis and validation	performed experiments and contributed to data analysis and validation	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Validation	YES
1933255	17668054	AM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1933255	17668054	AM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1933255	17668054	AM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1933255	17668054	CH	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1933255	17668054	EL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1933255	17668054	GD	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Edited the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
1933255	17668054	GD	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Edited the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1933255	17668054	GD	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Edited the manuscript	Edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
1933255	17668054	GM	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1933255	17668054	GM	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1933255	17668054	MT	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1933255	17668054	MT	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1933255	17668054	MT	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1933255	17668054	PD	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1933255	17668054	VS	PLoS5	Conceived and designed the experiments|Analyzed the data|Edited the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1933255	17668054	VS	PLoS5	Conceived and designed the experiments|Analyzed the data|Edited the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
1933255	17668054	VS	PLoS5	Conceived and designed the experiments|Analyzed the data|Edited the manuscript	Edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
4619845	26539490	Kyoji Hagiwara	2	contributed equally to this work	contributed equally to this work	-	-	NO
4619845	26539490	Pan He	2	contributed equally to this work	contributed equally to this work	-	-	NO
4415792	25928216	CLLC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415792	25928216	CZHL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4415792	25928216	JL	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4415792	25928216	JP	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415792	25928216	JZ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415792	25928216	PG	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4415792	25928216	PLL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4415792	25928216	QY	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415792	25928216	QY	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415792	25928216	SMJMY	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4415792	25928216	WJC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415792	25928216	XJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415792	25928216	XJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415792	25928216	XJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415792	25928216	XJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415792	25928216	ZL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1933256	17668073	AB	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1933256	17668073	DC	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1933256	17668073	HT	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1933256	17668073	HT	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1933256	17668073	KF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1933256	17668073	KF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1933256	17668073	KF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5744481	29312429	All the authors	2	participated in data analysis and interpretation, and contributed to the writing and editing of the manuscript	participated in data analysis and interpretation, and contributed to the writing and editing of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5744481	29312429	CZ	2	conceived the ideas for the study|contributed to the experimentation	conceived the ideas for the study	Conceived and designed the experiments	Conceptualization	YES
5744481	29312429	CZ	2	conceived the ideas for the study|contributed to the experimentation	contributed to the experimentation	Performed the experiments	Investigation	YES
5744481	29312429	HL	2	contributed to the experimentation	contributed to the experimentation	Performed the experiments	Investigation	YES
5744481	29312429	MZ	2	conceived the ideas for the study	conceived the ideas for the study	Conceived and designed the experiments	Conceptualization	YES
5293700	28168572	AG	2	participated in the design of the study, and supervised the research work|drafted the original manuscript	participated in the design of the study, and supervised the research work	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Supervision	YES
5293700	28168572	AG	2	participated in the design of the study, and supervised the research work|drafted the original manuscript	drafted the original manuscript	Wrote the paper	Writing - Original Draft	YES
5293700	28168572	AT	2	carried out the experiments|drafted the original manuscript	carried out the experiments	Performed the experiments	Investigation	YES
5293700	28168572	AT	2	carried out the experiments|drafted the original manuscript	drafted the original manuscript	Wrote the paper	Writing - Original Draft	YES
5293700	28168572	All	2	datasets on which the conclusions of the manuscript rely are presented in the main paper	datasets on which the conclusions of the manuscript rely are presented in the main paper	-	-	NO
5293700	28168572	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5293700	28168572	HB	2	performed the angiogenesis in vitro and in vivo experiments	performed the angiogenesis in vitro and in vivo experiments	Performed the experiments	Investigation	YES
5293700	28168572	MG	2	participated in the fermentation process	participated in the fermentation process	Performed the experiments	Investigation	YES
5293700	28168572	MM	2	performed the angiogenesis in vitro and in vivo experiments	performed the angiogenesis in vitro and in vivo experiments	Performed the experiments	Investigation	YES
5293700	28168572	NFM	2	participated in the affinity chromatography experiment	participated in the affinity chromatography experiment	Performed the experiments	Investigation	YES
5293700	28168572	NM	2	performed the angiogenesis in vitro and in vivo experiments	performed the angiogenesis in vitro and in vivo experiments	Performed the experiments	Investigation	YES
5293700	28168572	RA	2	produced and provided the cdna	produced and provided the cdna	Performed the experiments	Investigation	YES
5293700	28168572	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
4283412	25271254	DG	2	performed experiments and analysed data	performed experiments and analysed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4283412	25271254	GJG	2	devised the study, analysed the data and wrote the manuscript	devised the study, analysed the data and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
4283412	25271254	JVS	2	devised the study, analysed the data and wrote the manuscript	devised the study, analysed the data and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
4283412	25271254	KML	2	performed experiments and analysed data	performed experiments and analysed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4283412	25271254	RD	2	performed experiments and analysed data	performed experiments and analysed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4283412	25271254	RJBN	2	devised the study, analysed the data and wrote the manuscript	devised the study, analysed the data and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
5663151	29084524	AM	2	conceived the study|analyzed data|prepared the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5663151	29084524	AM	2	conceived the study|analyzed data|prepared the manuscript	analyzed data	Analyzed the data	Formal analysis	YES
5663151	29084524	AM	2	conceived the study|analyzed data|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5663151	29084524	EB	2	performed the comparative genomic analysis|analyzed data|prepared the manuscript	performed the comparative genomic analysis	Performed the experiments	Investigation	YES
5663151	29084524	EB	2	performed the comparative genomic analysis|analyzed data|prepared the manuscript	analyzed data	Analyzed the data	Formal analysis	YES
5663151	29084524	EB	2	performed the comparative genomic analysis|analyzed data|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5663151	29084524	EP	2	conceived the study|performed experiments|performed the comparative genomic analysis|analyzed data|prepared the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5663151	29084524	EP	2	conceived the study|performed experiments|performed the comparative genomic analysis|analyzed data|prepared the manuscript	performed experiments	Performed the experiments	Investigation	YES
5663151	29084524	EP	2	conceived the study|performed experiments|performed the comparative genomic analysis|analyzed data|prepared the manuscript	performed the comparative genomic analysis	Performed the experiments	Investigation	YES
5663151	29084524	EP	2	conceived the study|performed experiments|performed the comparative genomic analysis|analyzed data|prepared the manuscript	analyzed data	Analyzed the data	Formal analysis	YES
5663151	29084524	EP	2	conceived the study|performed experiments|performed the comparative genomic analysis|analyzed data|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5663151	29084524	MF	2	analyzed ngs data and performed snps and indels calling|analyzed data|prepared the manuscript	analyzed ngs data and performed snps and indels calling	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5663151	29084524	MF	2	analyzed ngs data and performed snps and indels calling|analyzed data|prepared the manuscript	analyzed data	Analyzed the data	Formal analysis	YES
5663151	29084524	MF	2	analyzed ngs data and performed snps and indels calling|analyzed data|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5663151	29084524	MV	2	prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5663151	29084524	RF	2	conceived the study|analyzed data|prepared the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5663151	29084524	RF	2	conceived the study|analyzed data|prepared the manuscript	analyzed data	Analyzed the data	Formal analysis	YES
5663151	29084524	RF	2	conceived the study|analyzed data|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5663151	29084524	SB	2	prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5663151	29084524	VCS	2	prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
1933591	17684554	MN	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1933591	17684554	MN	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1933591	17684554	YN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1933591	17684554	YN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1933591	17684554	YN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1933591	17684554	YN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1933591	17684554	YN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415793	25927609	BBF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415793	25927609	BBF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415793	25927609	BBF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415793	25927609	BBF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415793	25927609	BBF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415793	25927609	NTS	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415793	25927609	NTS	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415793	25927609	PSM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415793	25927609	PSM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415793	25927609	PSM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415793	25927609	SKB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415793	25927609	SKB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415793	25927609	SKB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4619847	26539502	Jingchun Sun	2	contributed equally	contributed equally	-	-	NO
4619847	26539502	Yukun Chen	2	contributed equally	contributed equally	-	-	NO
5293708	28168573	AAK	2	the knut and alice wallenberg foundation and the novo nordisk foundation	the knut and alice wallenberg foundation and the novo nordisk foundation	-	-	NO
5293708	28168573	AB	2	the knut and alice wallenberg foundation and the novo nordisk foundation	the knut and alice wallenberg foundation and the novo nordisk foundation	-	-	NO
5293708	28168573	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5293708	28168573	DB	2	designed and performed part of the experiments|edited the manuscript	designed and performed part of the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5293708	28168573	DB	2	designed and performed part of the experiments|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5293708	28168573	JN	2	conceived the study|edited the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5293708	28168573	JN	2	conceived the study|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5293708	28168573	MG	2	designed and performed part of the experiments|edited the manuscript	designed and performed part of the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5293708	28168573	MG	2	designed and performed part of the experiments|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5293708	28168573	VS	2	conceived the study|edited the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5293708	28168573	VS	2	conceived the study|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5293708	28168573	YW	2	designed and performed most of the experiments|wrote the manuscript	designed and performed most of the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5293708	28168573	YW	2	designed and performed most of the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5664567	29089035	CP	2	prepared experimental plants	prepared experimental plants	Performed the experiments	Investigation	YES
5664567	29089035	CYZ	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5664567	29089035	JS	2	collected data and carried out all data analyses	collected data and carried out all data analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5664567	29089035	JSH	2	conceptualized the idea|revised the manuscript	conceptualized the idea	Conceived and designed the experiments	Conceptualization	YES
5664567	29089035	JSH	2	conceptualized the idea|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5664567	29089035	SMF	2	performed the experiments and wrote the manuscript|collected data and carried out all data analyses	performed the experiments and wrote the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5664567	29089035	SMF	2	performed the experiments and wrote the manuscript|collected data and carried out all data analyses	collected data and carried out all data analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5744616	29312430	GK	2	wrote the grant, planned the study, performed the experiments and wrote the paper	wrote the grant, planned the study, performed the experiments and wrote the paper	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
5744616	29312430	HN	2	performed chemical analyses	performed chemical analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5744616	29312430	MT	2	planned the study, performed the experiments and the statistics, wrote the paper	planned the study, performed the experiments and the statistics, wrote the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
4331003	25568309	DWA	1	Conception, design and analysis|Constructed strains and plasmids|Performed experiments|Wrote the manuscript	Conception, design and analysis	Conceived and designed the experiments	Conceptualization	YES
4331003	25568309	DWA	1	Conception, design and analysis|Constructed strains and plasmids|Performed experiments|Wrote the manuscript	Constructed strains and plasmids	Performed the experiments	Investigation	YES
4331003	25568309	DWA	1	Conception, design and analysis|Constructed strains and plasmids|Performed experiments|Wrote the manuscript	Performed experiments	Performed the experiments	Investigation	YES
4331003	25568309	DWA	1	Conception, design and analysis|Constructed strains and plasmids|Performed experiments|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4331003	25568309	JE	1	Conception, design and analysis|Wrote the manuscript	Conception, design and analysis	Conceived and designed the experiments	Conceptualization	YES
4331003	25568309	JE	1	Conception, design and analysis|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4331003	25568309	LJW	1	Conception, design and analysis|Constructed strains and plasmids|Wrote the manuscript	Conception, design and analysis	Conceived and designed the experiments	Conceptualization	YES
4331003	25568309	LJW	1	Conception, design and analysis|Constructed strains and plasmids|Wrote the manuscript	Constructed strains and plasmids	Performed the experiments	Investigation	YES
4331003	25568309	LJW	1	Conception, design and analysis|Constructed strains and plasmids|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
1933592	17684555	IE	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1933592	17684555	IE	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1933592	17684555	IE	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1933592	17684555	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1933592	17684555	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1933592	17684555	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1933592	17684555	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1933592	17684555	OM	PLoS5	Conceived and designed the experiments|Wrote the paper|These authors share seniority	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1933592	17684555	OM	PLoS5	Conceived and designed the experiments|Wrote the paper|These authors share seniority	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1933592	17684555	OM	PLoS5	Conceived and designed the experiments|Wrote the paper|These authors share seniority	These authors share seniority	-	-	NO
1933592	17684555	PG	PLoS5	Conceived and designed the experiments|Wrote the paper|These authors share seniority	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1933592	17684555	PG	PLoS5	Conceived and designed the experiments|Wrote the paper|These authors share seniority	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1933592	17684555	PG	PLoS5	Conceived and designed the experiments|Wrote the paper|These authors share seniority	These authors share seniority	-	-	NO
1933592	17684555	SM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1933592	17684555	YB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5296263	28176283	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5296263	28176283	DPN	2	designed and coordinated the study, carrying out the experimental work|drafted the manuscript	designed and coordinated the study, carrying out the experimental work	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Project administration	YES
5296263	28176283	DPN	2	designed and coordinated the study, carrying out the experimental work|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5296263	28176283	GL	2	participated in design of the study and helped drafting and reviewing the manuscript	participated in design of the study and helped drafting and reviewing the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5296263	28176283	MFG	2	participated in design of the study and helped drafting and reviewing the manuscript	participated in design of the study and helped drafting and reviewing the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5296263	28176283	SP	2	designed and coordinated the study, carrying out the experimental work|highly contributed for the manuscript revision and submission	designed and coordinated the study, carrying out the experimental work	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Project administration	YES
5296263	28176283	SP	2	designed and coordinated the study, carrying out the experimental work|highly contributed for the manuscript revision and submission	highly contributed for the manuscript revision and submission	Wrote the paper	Writing - Review & Editing	YES
5744637	29312428	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5744637	29312428	BC	2	performed the quality characterization	performed the quality characterization	Performed the experiments	Investigation	YES
5744637	29312428	CB	2	participated in the establishment of the field trials, and performed the agronomic characterization|coordinated and participated in the acquisition of quality data, and participated in the manuscript revision	participated in the establishment of the field trials, and performed the agronomic characterization	Performed the experiments	Investigation	YES
5744637	29312428	CB	2	participated in the establishment of the field trials, and performed the agronomic characterization|coordinated and participated in the acquisition of quality data, and participated in the manuscript revision	coordinated and participated in the acquisition of quality data, and participated in the manuscript revision	Performed the experiments|Wrote the paper	Investigation|Project administration|Writing - Review & Editing	YES
5744637	29312428	JG	2	performed the analysis of the agronomic data, and critically participated in the manuscript revision	performed the analysis of the agronomic data, and critically participated in the manuscript revision	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
5744637	29312428	MB	2	performed the quality characterization	performed the quality characterization	Performed the experiments	Investigation	YES
5744637	29312428	MCVP	2	designed and coordinated the study and participated in the drafting and revising of the manuscript	designed and coordinated the study and participated in the drafting and revising of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft|Writing - Review & Editing	YES
5744637	29312428	MLA	2	performed the dna isolation and the ssr genotyping, the analysis of the molecular and quality data, and drafted the manuscript	performed the dna isolation and the ssr genotyping, the analysis of the molecular and quality data, and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5744637	29312428	MP	2	participated in the establishment of the field trials, and performed the agronomic characterization	participated in the establishment of the field trials, and performed the agronomic characterization	Performed the experiments	Investigation	YES
5744637	29312428	MRB	2	coordinated and participated in the acquisition of quality data, and participated in the manuscript revision	coordinated and participated in the acquisition of quality data, and participated in the manuscript revision	Performed the experiments|Wrote the paper	Investigation|Project administration|Writing - Review & Editing	YES
5744637	29312428	PMRM-M	2	coordinated the field trials and performed the agronomic characterization	coordinated the field trials and performed the agronomic characterization	Performed the experiments	Investigation|Project administration	YES
5744637	29312428	The authors	2	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	Performed the experiments	Investigation	YES
5744637	29312428	ZS	2	participated in the analysis of the molecular and phenotypic data, and critically participated in the manuscript revision	participated in the analysis of the molecular and phenotypic data, and critically participated in the manuscript revision	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
4415794	25928845	AM	PLoS5	Contributed discussion to improve the manuscript|Conducted field work|Thuja fossil records	Contributed discussion to improve the manuscript	Wrote the paper	Writing - Review & Editing	YES
4415794	25928845	AM	PLoS5	Contributed discussion to improve the manuscript|Conducted field work|Thuja fossil records	Conducted field work	Performed the experiments	Investigation	YES
4415794	25928845	AM	PLoS5	Contributed discussion to improve the manuscript|Conducted field work|Thuja fossil records	Thuja fossil records	-	-	NO
4415794	25928845	CQT	PLoS5	Analyzed the data|Wrote the paper|Conceived and designed this study|Conducted field work	Analyzed the data	Analyzed the data	Formal analysis	YES
4415794	25928845	CQT	PLoS5	Analyzed the data|Wrote the paper|Conceived and designed this study|Conducted field work	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415794	25928845	CQT	PLoS5	Analyzed the data|Wrote the paper|Conceived and designed this study|Conducted field work	Conceived and designed this study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415794	25928845	CQT	PLoS5	Analyzed the data|Wrote the paper|Conceived and designed this study|Conducted field work	Conducted field work	Performed the experiments	Investigation	YES
4415794	25928845	KR	PLoS5	Contributed discussion to improve the manuscript|Helped literature collection|Helped in editing the manuscript	Contributed discussion to improve the manuscript	Wrote the paper	Writing - Review & Editing	YES
4415794	25928845	KR	PLoS5	Contributed discussion to improve the manuscript|Helped literature collection|Helped in editing the manuscript	Helped literature collection	-	Formal analysis	YES
4415794	25928845	KR	PLoS5	Contributed discussion to improve the manuscript|Helped literature collection|Helped in editing the manuscript	Helped in editing the manuscript	Wrote the paper	Writing - Review & Editing	YES
4415794	25928845	KS	PLoS5	Thuja specimens	Thuja specimens	Performed the experiments	Investigation	YES
4415794	25928845	LYH	PLoS5	Created the maps of the study sites	Created the maps of the study sites	-	-	NO
4415794	25928845	MO	PLoS5	Conducted field work|Contributed ideas and discussion to improve the manuscript	Conducted field work	Performed the experiments	Investigation	YES
4415794	25928845	MO	PLoS5	Conducted field work|Contributed ideas and discussion to improve the manuscript	Contributed ideas and discussion to improve the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
4415794	25928845	SRY	PLoS5	Identified plant species in the field	Identified plant species in the field	Performed the experiments	Investigation	YES
4415794	25928845	SZ	PLoS5	Assisted in field work	Assisted in field work	Performed the experiments	Investigation	YES
4415794	25928845	YY	PLoS5	Conceived and designed this study|Arranged and conducted field work|Contributed discussion to improve the manuscript	Conceived and designed this study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415794	25928845	YY	PLoS5	Conceived and designed this study|Arranged and conducted field work|Contributed discussion to improve the manuscript	Arranged and conducted field work	Performed the experiments	Investigation	YES
4415794	25928845	YY	PLoS5	Conceived and designed this study|Arranged and conducted field work|Contributed discussion to improve the manuscript	Contributed discussion to improve the manuscript	Wrote the paper	Writing - Review & Editing	YES
1933593	17684546	DV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1933593	17684546	DV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1933593	17684546	DV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1933593	17684546	DV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1933593	17684546	TS	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1933593	17684546	TS	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5664786	29089022	All authors	2	analyzed data and reviewed the manuscript	analyzed data and reviewed the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5664786	29089022	CP	2	conducted marker development, genotyping, and mapping|wrote the manuscript	conducted marker development, genotyping, and mapping	Performed the experiments	Investigation	YES
5664786	29089022	CP	2	conducted marker development, genotyping, and mapping|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5664786	29089022	FM	2	conducted marker development, genotyping, and mapping	conducted marker development, genotyping, and mapping	Performed the experiments	Investigation	YES
5664786	29089022	GL	2	conducted marker development, genotyping, and mapping|wrote the manuscript	conducted marker development, genotyping, and mapping	Performed the experiments	Investigation	YES
5664786	29089022	GL	2	conducted marker development, genotyping, and mapping|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5664786	29089022	LY	2	conceived the project and designed the experiments|wrote the manuscript	conceived the project and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5664786	29089022	LY	2	conceived the project and designed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5664786	29089022	PSB	2	conceived the project and designed the experiments|wrote the manuscript	conceived the project and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5664786	29089022	PSB	2	conceived the project and designed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5664786	29089022	RB	2	conducted marker development, genotyping, and mapping|wrote the manuscript	conducted marker development, genotyping, and mapping	Performed the experiments	Investigation	YES
5664786	29089022	RB	2	conducted marker development, genotyping, and mapping|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5664786	29089022	TH	2	conducted marker development, genotyping, and mapping	conducted marker development, genotyping, and mapping	Performed the experiments	Investigation	YES
5664786	29089022	VB	2	processed the genotyping-by-sequencing data and performed snp calling	processed the genotyping-by-sequencing data and performed snp calling	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
4331008	25588944	KM	2	prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
4331008	25588944	SLW	2	prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
4415795	25927920	AB	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4415795	25927920	AB	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4415795	25927920	AD	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415795	25927920	AD	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415795	25927920	AD	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415795	25927920	ALC	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415795	25927920	ALC	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415795	25927920	FP	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415795	25927920	GDN	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415795	25927920	GDN	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415795	25927920	GT	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4415795	25927920	GT	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4415795	25927920	KG	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4415795	25927920	KG	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4415795	25927920	LG	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1933594	17684547	AN	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1933594	17684547	AN	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1933594	17684547	IS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1933594	17684547	IS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1933594	17684547	JE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1933594	17684547	JE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1933594	17684547	JE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1933594	17684547	JE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1933594	17684547	KG	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5744647	29312400	MB	5	wrote this manuscript with revisions and editorial advice from VW	wrote this manuscript with revisions and editorial advice from VW	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5149654	27938639	A.B.	2	supervised the study, collaborated in its design, development, and data analysis, and conducted email follow-up during data collection|who provided critical revision	supervised the study, collaborated in its design, development, and data analysis, and conducted email follow-up during data collection	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology|Supervision	YES
5149654	27938639	A.B.	2	supervised the study, collaborated in its design, development, and data analysis, and conducted email follow-up during data collection|who provided critical revision	who provided critical revision	Wrote the paper	Writing - Review & Editing	YES
5664820	29089020	CKCJ	2	designed and carried out the experiments, including rna extraction, rna seq analysis, differential gene expression analysis and data interpretation, and wrote the article	designed and carried out the experiments, including rna extraction, rna seq analysis, differential gene expression analysis and data interpretation, and wrote the article	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5664820	29089020	MH	2	provided the server for data analysis, guidance on computational analysis of the sequence data and interpretation	provided the server for data analysis, guidance on computational analysis of the sequence data and interpretation	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources|Supervision	YES
5664820	29089020	PKK	2	designed, wrote and provided guidance on the project, and helped format and edit the manuscript	designed, wrote and provided guidance on the project, and helped format and edit the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
5664820	29089020	TDT	2	provided the server for data analysis, guidance on computational analysis of the sequence data and interpretation	provided the server for data analysis, guidance on computational analysis of the sequence data and interpretation	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources|Supervision	YES
1933595	17684557	ES	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1933595	17684557	ES	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1933595	17684557	ES	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1933595	17684557	ES	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1933595	17684557	ES	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1933595	17684557	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1933595	17684557	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1933595	17684557	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1933595	17684557	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1933595	17684557	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4880859	27231439	AO	2	assisted in data collection and sample analysis	assisted in data collection and sample analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4880859	27231439	CG	2	assisted in data collection and sample analysis	assisted in data collection and sample analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4880859	27231439	CR	2	is the director of the exercise and sport nutrition lab	is the director of the exercise and sport nutrition lab	-	-	NO
4880859	27231439	EG	2	assisted with data collection, sample analysis, and review of dietary inventories as the rd on staff	assisted with data collection, sample analysis, and review of dietary inventories as the rd on staff	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4880859	27231439	KL	2	assisted in designing the study, writing the grant, study coordination, data collection, data analysis, and manuscript preparation	assisted in designing the study, writing the grant, study coordination, data collection, data analysis, and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Project administration|Writing - Original Draft	YES
4880859	27231439	MG	2	assisted in research design and consultation	assisted in research design and consultation	Conceived and designed the experiments	-	YES
4880859	27231439	RD	2	assisted in data collection and sample analysis	assisted in data collection and sample analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4880859	27231439	SC	2	assisted in study consultation	assisted in study consultation	-	-	NO
4880859	27231439	SMT	2	assisted in study consultation	assisted in study consultation	-	-	NO
4880859	27231439	SR	2	assisted in study consultation	assisted in study consultation	-	-	NO
4880859	27231439	SS	2	assisted in data collection and sample analysis	assisted in data collection and sample analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4339119	25527291	AQUA	2	prm analysis in the laboratory, performed all mass spectrometry and analyzed the data	prm analysis in the laboratory, performed all mass spectrometry and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4339119	25527291	CG	2	discovered ubiquitin phosphorylation by pink1 in vitro	discovered ubiquitin phosphorylation by pink1 in vitro	Performed the experiments	Investigation	YES
4339119	25527291	CMJ	2	performed stability measurements	performed stability measurements	Performed the experiments	Investigation	YES
4339119	25527291	DK	2	solved and refined the phosphoub crystal structure|wrote the manuscript with input from all authors	solved and refined the phosphoub crystal structure	-	-	NO
4339119	25527291	DK	2	solved and refined the phosphoub crystal structure|wrote the manuscript with input from all authors	wrote the manuscript with input from all authors	Wrote the paper	Writing - Original Draft	YES
4339119	25527291	JNP	2	generated reagents and provided expertise and protocols	generated reagents and provided expertise and protocols	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4339119	25527291	JW	2	performed nmr analysis	performed nmr analysis	Performed the experiments	Investigation	YES
4339119	25527291	KNS	2	discovered ubiquitin phosphorylation by pink1 in vitro	discovered ubiquitin phosphorylation by pink1 in vitro	Performed the experiments	Investigation	YES
4339119	25527291	SMVF	2	performed nmr analysis	performed nmr analysis	Performed the experiments	Investigation	YES
4339119	25527291	TW	2	solved and refined the phosphoub crystal structure|discovered ubiquitin phosphorylation by pink1 in vitro	solved and refined the phosphoub crystal structure	-	-	NO
4339119	25527291	TW	2	solved and refined the phosphoub crystal structure|discovered ubiquitin phosphorylation by pink1 in vitro	discovered ubiquitin phosphorylation by pink1 in vitro	Performed the experiments	Investigation	YES
4415797	25928885	DG	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415797	25928885	DG	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415797	25928885	DG	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415797	25928885	DG	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415797	25928885	GZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415797	25928885	GZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415797	25928885	GZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415797	25928885	GZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415797	25928885	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415797	25928885	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415797	25928885	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415797	25928885	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415797	25928885	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5302012	28138939	JIQ	1	Planning and designing of study	Planning and designing of study	Conceived and designed the experiments	Methodology	YES
5302012	28138939	MI	1	Planning and designing of study	Planning and designing of study	Conceived and designed the experiments	Methodology	YES
3858885	24376388	Fengbo Wu	2	contributed equally to this work	contributed equally to this work	-	-	NO
3858885	24376388	Ting Xu	2	contributed equally to this work	contributed equally to this work	-	-	NO
5758543	29354151	CC	PLoS52	prepared the materials	prepared the materials	Performed the experiments	Investigation	YES
5758543	29354151	CD	PLoS52	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5758543	29354151	GZ	PLoS52	prepared the materials	prepared the materials	Performed the experiments	Investigation	YES
5758543	29354151	J-LY	PLoS52	suggested the histological experiment|revised the manuscript	suggested the histological experiment	Performed the experiments	Investigation	YES
5758543	29354151	J-LY	PLoS52	suggested the histological experiment|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5758543	29354151	JG	PLoS52	analyzed the data|prepared dna and rna samples|performed gene expression and paraffin section analyses|prepared the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5758543	29354151	JG	PLoS52	analyzed the data|prepared dna and rna samples|performed gene expression and paraffin section analyses|prepared the manuscript	prepared dna and rna samples	Performed the experiments	Investigation	YES
5758543	29354151	JG	PLoS52	analyzed the data|prepared dna and rna samples|performed gene expression and paraffin section analyses|prepared the manuscript	performed gene expression and paraffin section analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5758543	29354151	JG	PLoS52	analyzed the data|prepared dna and rna samples|performed gene expression and paraffin section analyses|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5758543	29354151	KC	PLoS52	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5758543	29354151	LG	PLoS52	prepared the materials	prepared the materials	Performed the experiments	Investigation	YES
5758543	29354151	LW	PLoS52	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5758543	29354151	QW	PLoS52	prepared dna and rna samples	prepared dna and rna samples	Performed the experiments	Investigation	YES
5758543	29354151	TD	PLoS52	prepared the materials	prepared the materials	Performed the experiments	Investigation	YES
5758543	29354151	WF	PLoS52	prepared the materials	prepared the materials	Performed the experiments	Investigation	YES
5758543	29354151	XW	PLoS52	prepared the materials	prepared the materials	Performed the experiments	Investigation	YES
5758543	29354151	YL	PLoS52	analyzed the data|prepared dna and rna samples	analyzed the data	Analyzed the data	Formal analysis	YES
5758543	29354151	YL	PLoS52	analyzed the data|prepared dna and rna samples	prepared dna and rna samples	Performed the experiments	Investigation	YES
4886409	27247543	AC	4	data interpretation was undertaken by	data interpretation was undertaken by	Analyzed the data	Formal analysis	YES
4886409	27247543	EM	4	data were collected and analysed by	data were collected and analysed by	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4886409	27247543	FT	4	The study was designed by|data interpretation was undertaken by|Manuscript preparation was performed by	The study was designed by	Conceived and designed the experiments	Methodology	YES
4886409	27247543	FT	4	The study was designed by|data interpretation was undertaken by|Manuscript preparation was performed by	data interpretation was undertaken by	Analyzed the data	Formal analysis	YES
4886409	27247543	FT	4	The study was designed by|data interpretation was undertaken by|Manuscript preparation was performed by	Manuscript preparation was performed by	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4886409	27247543	GG	4	The study was designed by|data interpretation was undertaken by|Manuscript preparation was performed by	The study was designed by	Conceived and designed the experiments	Methodology	YES
4886409	27247543	GG	4	The study was designed by|data interpretation was undertaken by|Manuscript preparation was performed by	data interpretation was undertaken by	Analyzed the data	Formal analysis	YES
4886409	27247543	GG	4	The study was designed by|data interpretation was undertaken by|Manuscript preparation was performed by	Manuscript preparation was performed by	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4886409	27247543	GP	4	data were collected and analysed by	data were collected and analysed by	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4886409	27247543	IS	4	data were collected and analysed by	data were collected and analysed by	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4886409	27247543	MP	4	data were collected and analysed by|data were collected and analysed by	data were collected and analysed by	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4886409	27247543	MP	4	data were collected and analysed by|data were collected and analysed by	data were collected and analysed by	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4886409	27247543	SO	4	data were collected and analysed by	data were collected and analysed by	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4886409	27247543	SR	4	data were collected and analysed by	data were collected and analysed by	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
1933596	17684558	LX	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1933596	17684558	LX	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1933596	17684558	RL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1933596	17684558	RL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1933596	17684558	RL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1933596	17684558	SJ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1933596	17684558	SJ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1933596	17684558	SJ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1933596	17684558	SR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1933596	17684558	SR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1933596	17684558	SR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1933596	17684558	SR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1933596	17684558	SS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1933596	17684558	SS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5667528	29096603	BC	2	conducted the field experiments and collected the data	conducted the field experiments and collected the data	Performed the experiments	Investigation	YES
5667528	29096603	DC	2	analyzed the data and wrote the paper	analyzed the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5667528	29096603	EOA	2	contributed to bioinformatics analysis	contributed to bioinformatics analysis	-	Formal analysis	YES
5667528	29096603	LN	2	conducted the field experiments and collected the data	conducted the field experiments and collected the data	Performed the experiments	Investigation	YES
5667528	29096603	SB	2	contributed to bioinformatics analysis	contributed to bioinformatics analysis	-	Formal analysis	YES
5667528	29096603	ST	2	contributed to bioinformatics analysis	contributed to bioinformatics analysis	-	Formal analysis	YES
5667528	29096603	TDG	2	conducted the field experiments and collected the data	conducted the field experiments and collected the data	Performed the experiments	Investigation	YES
5667528	29096603	VP	2	participated in the genotyping work	participated in the genotyping work	Performed the experiments	Investigation	YES
5667528	29096603	VR	2	contributed to bioinformatics analysis|conducted the field experiments and collected the data	contributed to bioinformatics analysis	-	Formal analysis	YES
5667528	29096603	VR	2	contributed to bioinformatics analysis|conducted the field experiments and collected the data	conducted the field experiments and collected the data	Performed the experiments	Investigation	YES
5667528	29096603	XA	2	contributed to bioinformatics analysis	contributed to bioinformatics analysis	-	Formal analysis	YES
5667528	29096603	ZL	2	conducted the field experiments and collected the data	conducted the field experiments and collected the data	Performed the experiments	Investigation	YES
4891923	27274715	All authors	2	worked collectively to design the study	worked collectively to design the study	Conceived and designed the experiments|Performed the experiments	Methodology	YES
4891923	27274715	BH	2	helped in drafting the manuscript	helped in drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
4891923	27274715	GE	2	was the primary investigator and supervised all study recruitment	was the primary investigator and supervised all study recruitment	Performed the experiments	Investigation|Supervision	YES
4891923	27274715	MA	2	performed the statistical analysis|helped in drafting the manuscript	performed the statistical analysis	Analyzed the data	Formal analysis	YES
4891923	27274715	MA	2	performed the statistical analysis|helped in drafting the manuscript	helped in drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
4891923	27274715	PH	2	helped in drafting the manuscript	helped in drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
5758561	29354149	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5307391	28194744	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5307391	28194744	LJ	2	was primarily responsible for the designing experimental program	was primarily responsible for the designing experimental program	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5307391	28194744	RZ	2	offered some valuable thoughts and advice for modifying the manuscript	offered some valuable thoughts and advice for modifying the manuscript	Wrote the paper	Writing - Review & Editing	YES
5307391	28194744	Technology Innovation Talents	2	in universities of henan province	in universities of henan province	-	-	NO
5307391	28194744	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5307391	28194744	XL	2	offered some valuable thoughts and advice for modifying the manuscript	offered some valuable thoughts and advice for modifying the manuscript	Wrote the paper	Writing - Review & Editing	YES
4415799	25927361	DC	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415799	25927361	DC	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415799	25927361	DS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415799	25927361	DS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415799	25927361	DS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415799	25927361	DS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415799	25927361	KS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415799	25927361	KS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415799	25927361	KS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415799	25927361	KS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415799	25927361	OT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415799	25927361	OT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415799	25927361	OT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415799	25927361	OT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415799	25927361	TH	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415799	25927361	TH	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4339124	25535246	AMB	2	performed the experiments of the themis and shp1 study	performed the experiments of the themis and shp1 study	Performed the experiments	Investigation	YES
4339124	25535246	BM	2	conceived and developed the lck s59a mice	conceived and developed the lck s59a mice	Conceived and designed the experiments	Conceptualization	YES
4339124	25535246	CG	2	conceived and developed the lck s59a mice	conceived and developed the lck s59a mice	Conceived and designed the experiments	Conceptualization	YES
4339124	25535246	GF	2	provided key reagents and help with data analysis	provided key reagents and help with data analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
4339124	25535246	KCM	2	prepared reagents and provided technical assistance	prepared reagents and provided technical assistance	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4339124	25535246	KK	2	performed the experiments of the themis and shp1 study	performed the experiments of the themis and shp1 study	Performed the experiments	Investigation	YES
4339124	25535246	NRJG	2	provided key reagents and help with data analysis	provided key reagents and help with data analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
4339124	25535246	OA	2	initiated the project and conceived the experiments of the themis and shp1 study|wrote the manuscript with contributions from all authors	initiated the project and conceived the experiments of the themis and shp1 study	Conceived and designed the experiments	Conceptualization	YES
4339124	25535246	OA	2	initiated the project and conceived the experiments of the themis and shp1 study|wrote the manuscript with contributions from all authors	wrote the manuscript with contributions from all authors	Wrote the paper	Writing - Original Draft	YES
4339124	25535246	OD	2	helped in analysing the phospho-flow data	helped in analysing the phospho-flow data	Analyzed the data	Formal analysis	YES
4339124	25535246	PCS	2	provided recombinant grb2 sh3-gst and advised on far-western experiments	provided recombinant grb2 sh3-gst and advised on far-western experiments	Performed the experiments	Investigation	YES
4339124	25535246	RR	2	wrote the manuscript with contributions from all authors	wrote the manuscript with contributions from all authors	Wrote the paper	Writing - Original Draft	YES
4339124	25535246	S-PC	2	generated stable cd8 co-receptor expressing jurkat 1g4 cells	generated stable cd8 co-receptor expressing jurkat 1g4 cells	Performed the experiments	Investigation	YES
4339124	25535246	SMF	2	provided recombinant grb2 sh3-gst and advised on far-western experiments	provided recombinant grb2 sh3-gst and advised on far-western experiments	Performed the experiments	Investigation	YES
4339124	25535246	WP	2	initiated the project and conceived the experiments of the themis and shp1 study|performed the experiments of the themis and shp1 study|wrote the manuscript with contributions from all authors	initiated the project and conceived the experiments of the themis and shp1 study	Conceived and designed the experiments	Conceptualization	YES
4339124	25535246	WP	2	initiated the project and conceived the experiments of the themis and shp1 study|performed the experiments of the themis and shp1 study|wrote the manuscript with contributions from all authors	performed the experiments of the themis and shp1 study	Performed the experiments	Investigation	YES
4339124	25535246	WP	2	initiated the project and conceived the experiments of the themis and shp1 study|performed the experiments of the themis and shp1 study|wrote the manuscript with contributions from all authors	wrote the manuscript with contributions from all authors	Wrote the paper	Writing - Original Draft	YES
1933597	17684568	DJ	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1933597	17684568	DJ	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1933597	17684568	JJ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1933597	17684568	JJ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1933597	17684568	JJ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4901467	27293386	All authors	2	contributed to the conception of the experimental design and drafting of the manuscript	contributed to the conception of the experimental design and drafting of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Writing - Original Draft	YES
4901467	27293386	JJ	2	participated in data collection	participated in data collection	Performed the experiments	Investigation	YES
4901467	27293386	MM	2	participated in data collection	participated in data collection	Performed the experiments	Investigation	YES
4901467	27293386	PF	2	participated in data collection	participated in data collection	Performed the experiments	Investigation	YES
4901467	27293386	RV	2	participated in data collection	participated in data collection	Performed the experiments	Investigation	YES
4415800	25928358	AAME	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415800	25928358	AAME	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415800	25928358	AAME	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415800	25928358	AAME	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415800	25928358	AAME	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415800	25928358	FZ	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4415800	25928358	FZ	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415800	25928358	MWA	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415800	25928358	MWA	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415800	25928358	RM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415800	25928358	RM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415800	25928358	RM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415800	25928358	RM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5668952	29096601	CAG	2	planned the study and wrote the manuscript|performed the dna extraction study, the pcr study, and the melting curve study|analysed the samples using 16s rrna gene sequencing and shotgun metagenomics, and contributed to writing the manuscript	planned the study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5668952	29096601	CAG	2	planned the study and wrote the manuscript|performed the dna extraction study, the pcr study, and the melting curve study|analysed the samples using 16s rrna gene sequencing and shotgun metagenomics, and contributed to writing the manuscript	performed the dna extraction study, the pcr study, and the melting curve study	Performed the experiments	Investigation	YES
5668952	29096601	CAG	2	planned the study and wrote the manuscript|performed the dna extraction study, the pcr study, and the melting curve study|analysed the samples using 16s rrna gene sequencing and shotgun metagenomics, and contributed to writing the manuscript	analysed the samples using 16s rrna gene sequencing and shotgun metagenomics, and contributed to writing the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5668952	29096601	GB	2	managed sample collection and approved the manuscript	managed sample collection and approved the manuscript	Performed the experiments	Investigation	YES
5668952	29096601	JK	2	managed sample collection and approved the manuscript	managed sample collection and approved the manuscript	Performed the experiments	Investigation	YES
5668952	29096601	JW	2	contributed to laboratory experiment design, and manuscript editing	contributed to laboratory experiment design, and manuscript editing	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
5668952	29096601	LJH	2	planned the study and wrote the manuscript	planned the study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5668952	29096601	PC	2	managed sample collection and approved the manuscript	managed sample collection and approved the manuscript	Performed the experiments	Investigation	YES
5668952	29096601	SC	2	analysed the samples using 16s rrna gene sequencing and shotgun metagenomics, and contributed to writing the manuscript	analysed the samples using 16s rrna gene sequencing and shotgun metagenomics, and contributed to writing the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5668952	29096601	SM	2	analysed the samples using 16s rrna gene sequencing and shotgun metagenomics, and contributed to writing the manuscript	analysed the samples using 16s rrna gene sequencing and shotgun metagenomics, and contributed to writing the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5668952	29096601	UW	2	performed the primer aligning study	performed the primer aligning study	Performed the experiments	Investigation	YES
4619857	26539528	Enfeng Wang	2	have contributed equally to this work	have contributed equally to this work	-	-	NO
4619857	26539528	Lu Zhao	2	have contributed equally to this work	have contributed equally to this work	-	-	NO
5758583	29354147	BL	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5758583	29354147	XL	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5758583	29354147	XL	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5758583	29354147	XL	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5758583	29354147	XL	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5758583	29354147	YHY	PLoS52	supported the data determination	supported the data determination	-	-	NO
5758583	29354147	YPY	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5758583	29354147	YW	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
1933598	17684544	AE	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1933598	17684544	AF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1933598	17684544	AF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1933598	17684544	AF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1933598	17684544	AF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1933598	17684544	AR	PLoS5	Performed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1933598	17684544	AR	PLoS5	Performed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1933598	17684544	CB	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1933598	17684544	CB	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1933598	17684544	CM	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1933598	17684544	CM	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1933598	17684544	CO	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1933598	17684544	CO	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1933598	17684544	FW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1933598	17684544	GM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1933598	17684544	HF	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1933598	17684544	JH	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1933598	17684544	KH	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1933598	17684544	KH	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1933598	17684544	MA	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1933598	17684544	MK	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1933598	17684544	MK	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1933598	17684544	MP	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1933598	17684544	MS	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1933598	17684544	MW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1933598	17684544	NP	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1933598	17684544	NP	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1933598	17684544	PN	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1933598	17684544	PR	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1933598	17684544	RH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1933598	17684544	RL	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1933598	17684544	RL	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1933598	17684544	SS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1933598	17684544	SS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1933598	17684544	TB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1933598	17684544	TK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1933598	17684544	TK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1933598	17684544	UR	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5307404	28194743	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5307404	28194743	GQ	2	conducted the experiments and wrote the manuscript	conducted the experiments and wrote the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5307404	28194743	GY	2	conducted the experiments and wrote the manuscript	conducted the experiments and wrote the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5307404	28194743	WM	2	performed the data analyses	performed the data analyses	Analyzed the data	Formal analysis	YES
5307404	28194743	WZ	2	supervised the research	supervised the research	-	Supervision	YES
5307404	28194743	YH	2	performed the data analyses	performed the data analyses	Analyzed the data	Formal analysis	YES
5307404	28194743	YY	2	conducted the experiments and wrote the manuscript	conducted the experiments and wrote the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5307404	28194743	ZG	2	supervised the research	supervised the research	-	Supervision	YES
5307404	28194743	ZW	2	supervised the research and revised the manuscript	supervised the research and revised the manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
4339125	25582120	ARC	2	designed and performed most of the experiments and analysed the data	designed and performed most of the experiments and analysed the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
4339125	25582120	All authors	2	discussed the results and commented on the manuscript	discussed the results and commented on the manuscript	-	-	NO
4339125	25582120	CF	2	designed and performed most of the experiments and analysed the data	designed and performed most of the experiments and analysed the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
4339125	25582120	KO	2	executed the pulsed-field gel electrophoresis experiments in fig 4	executed the pulsed-field gel electrophoresis experiments in fig 4	Performed the experiments	Investigation	YES
4339125	25582120	MT	2	designed and supervised the study, analysed the data and wrote the manuscript	designed and supervised the study, analysed the data and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Supervision|Writing - Original Draft	YES
4339125	25582120	SB	2	designed and performed most of the experiments and analysed the data	designed and performed most of the experiments and analysed the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
4415801	25927525	JG	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415801	25927525	LQ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415801	25927525	LQ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415801	25927525	LQ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415801	25927525	LQ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415801	25927525	LQ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415801	25927525	LZ	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4415801	25927525	YL	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415801	25927525	YL	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415801	25927525	YS	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415801	25927525	YZ	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5309192	28197985	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5309192	28197985	JQ	2	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5309192	28197985	MY	2	carried out all the experiments	carried out all the experiments	Performed the experiments	Investigation	YES
5309192	28197985	YH	2	designed the experiments|carried out all the experiments|collected and calculated all data, created the tables and figures and wrote this manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5309192	28197985	YH	2	designed the experiments|carried out all the experiments|collected and calculated all data, created the tables and figures and wrote this manuscript	carried out all the experiments	Performed the experiments	Investigation	YES
5309192	28197985	YH	2	designed the experiments|carried out all the experiments|collected and calculated all data, created the tables and figures and wrote this manuscript	collected and calculated all data, created the tables and figures and wrote this manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Visualization|Writing - Original Draft	YES
5758588	29354140	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5758588	29354140	FdA	PLoS52	conceived and designed the experiments|all three revised the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5758588	29354140	FdA	PLoS52	conceived and designed the experiments|all three revised the manuscript	all three revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5758588	29354140	GO-A	PLoS52	contributed to the experimental work	contributed to the experimental work	Performed the experiments	Investigation	YES
5758588	29354140	JA	PLoS52	conceived and designed the experiments|all three revised the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5758588	29354140	JA	PLoS52	conceived and designed the experiments|all three revised the manuscript	all three revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5758588	29354140	MP	PLoS52	contributed to the experimental work	contributed to the experimental work	Performed the experiments	Investigation	YES
5758588	29354140	MS	PLoS52	contributed to the experimental work	contributed to the experimental work	Performed the experiments	Investigation	YES
5758588	29354140	RV	PLoS52	contributed to the data analysis and preparation of tables and figures	contributed to the data analysis and preparation of tables and figures	Analyzed the data	Formal analysis|Visualization	YES
5758588	29354140	SY	PLoS52	contributed to the data analysis and preparation of tables and figures	contributed to the data analysis and preparation of tables and figures	Analyzed the data	Formal analysis|Visualization	YES
5668977	29096602	CP	PLoS52	conceived and designed the experiments|conducted experiments|analyzed the data|wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5668977	29096602	CP	PLoS52	conceived and designed the experiments|conducted experiments|analyzed the data|wrote the manuscript	conducted experiments	Performed the experiments	Investigation	YES
5668977	29096602	CP	PLoS52	conceived and designed the experiments|conducted experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5668977	29096602	CP	PLoS52	conceived and designed the experiments|conducted experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5668977	29096602	DY	PLoS52	conducted experiments	conducted experiments	Performed the experiments	Investigation	YES
5668977	29096602	GL	PLoS52	conceived and designed the experiments|wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5668977	29096602	GL	PLoS52	conceived and designed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5668977	29096602	LC	PLoS52	conducted experiments	conducted experiments	Performed the experiments	Investigation	YES
5668977	29096602	LY	PLoS52	conducted experiments|helped to revise the manuscript	conducted experiments	Performed the experiments	Investigation	YES
5668977	29096602	LY	PLoS52	conducted experiments|helped to revise the manuscript	helped to revise the manuscript	Wrote the paper	Writing - Review & Editing	YES
5668977	29096602	XL	PLoS52	conducted experiments	conducted experiments	Performed the experiments	Investigation	YES
5668977	29096602	Y Zhang	PLoS52	conducted experiments	conducted experiments	Performed the experiments	Investigation	YES
5668977	29096602	Y Zheng	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5668977	29096602	YW	PLoS52	conducted experiments	conducted experiments	Performed the experiments	Investigation	YES
5668977	29096602	ZF	PLoS52	analyzed the data|helped to revise the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5668977	29096602	ZF	PLoS52	analyzed the data|helped to revise the manuscript	helped to revise the manuscript	Wrote the paper	Writing - Review & Editing	YES
4415802	25927991	ACSL	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415802	25927991	ACSL	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415802	25927991	FQO	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4415802	25927991	FSF	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4415802	25927991	FSR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415802	25927991	FSR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415802	25927991	FSR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415802	25927991	FSR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415802	25927991	JBM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415802	25927991	JBM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415802	25927991	JBM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415802	25927991	JBM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415802	25927991	JBM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415802	25927991	JCZ	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4928275	27366132	BS	2	primarily collected the data and aided in editing manuscript	primarily collected the data and aided in editing manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4928275	27366132	KS	2	primarily collected the data and aided in editing manuscript	primarily collected the data and aided in editing manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4928275	27366132	MH	2	assisted in the conceptualization of the study design, acquired study funding, and helped edit the manuscript	assisted in the conceptualization of the study design, acquired study funding, and helped edit the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Funding acquisition|Methodology|Writing - Review & Editing	YES
4928275	27366132	SE	2	helped conceptualize the study purposes, organized and analyzed the data, and wrote and edited the manuscript	helped conceptualize the study purposes, organized and analyzed the data, and wrote and edited the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Project administration|Writing - Original Draft|Writing - Review & Editing	YES
4928275	27366132	SK	2	also helped conceptualize the study, organized and analyzed the data, and helped write and edit the manuscript	also helped conceptualize the study, organized and analyzed the data, and helped write and edit the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Project administration|Writing - Original Draft|Writing - Review & Editing	YES
4928275	27366132	SR	2	oversaw the study design, manuscript layout, and was the primary editor of the manuscript	oversaw the study design, manuscript layout, and was the primary editor of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Review & Editing	YES
1933599	17684559	BM	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1933599	17684559	BM	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1933599	17684559	PH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1933599	17684559	PH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1933599	17684559	PH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1933599	17684559	PH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1933599	17684559	PH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1933599	17684559	WH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1933599	17684559	WH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1933599	17684559	WH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4619869	26539525	All authors	2	read and approved the final paper	read and approved the final paper	-	-	NO
4619869	26539525	Axel Newe	2	created the questionnaire, was part of the peer group, and helped to draft the paper	created the questionnaire, was part of the peer group, and helped to draft the paper	Wrote the paper	Writing - Original Draft	YES
4619869	26539525	Benjamin Trinczek	2	provided technical support, was part of the peer group, and helped to draft the paper	provided technical support, was part of the peer group, and helped to draft the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4619869	26539525	Brita Sedlmayr	2	analysed and discussed the results, supervised the methodological approach, and helped to draft the paper|contributed equally to this work	analysed and discussed the results, supervised the methodological approach, and helped to draft the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Supervision|Writing - Original Draft	YES
4619869	26539525	Brita Sedlmayr	2	analysed and discussed the results, supervised the methodological approach, and helped to draft the paper|contributed equally to this work	contributed equally to this work	-	-	NO
4619869	26539525	Caroline Lafitte	2	participated in a pretest, provided user advice, and helped to draft the paper	participated in a pretest, provided user advice, and helped to draft the paper	Wrote the paper	Writing - Original Draft	YES
4619869	26539525	Fleur Fritz	2	analysed and discussed the results, supervised the methodological approach, and helped to draft the paper|contributed equally to this work	analysed and discussed the results, supervised the methodological approach, and helped to draft the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Supervision|Writing - Original Draft	YES
4619869	26539525	Fleur Fritz	2	analysed and discussed the results, supervised the methodological approach, and helped to draft the paper|contributed equally to this work	contributed equally to this work	-	-	NO
4619869	26539525	Inaki Soto-Rey	2	managed the evaluation team, collected the data, and wrote the paper	managed the evaluation team, collected the data, and wrote the paper	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Investigation|Writing - Original Draft	YES
4619869	26539525	James Cunningham	2	developed the training material, was part of the peer group, and helped to draft the paper	developed the training material, was part of the peer group, and helped to draft the paper	Wrote the paper	Writing - Original Draft	YES
4619869	26539525	NDja	2	managed the evaluation team, collected the data, and wrote the paper	managed the evaluation team, collected the data, and wrote the paper	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Investigation|Writing - Original Draft	YES
4365034	25599992	CWJS	2	conceived and designed the investigation|wrote the manuscript with input from all other authors	conceived and designed the investigation	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
4365034	25599992	CWJS	2	conceived and designed the investigation|wrote the manuscript with input from all other authors	wrote the manuscript with input from all other authors	Wrote the paper	Writing - Original Draft	YES
4365034	25599992	JA	2	carried out iclip experiments	carried out iclip experiments	Performed the experiments	Investigation	YES
4365034	25599992	JK	2	carried out iclip experiments	carried out iclip experiments	Performed the experiments	Investigation	YES
4365034	25599992	JU	2	analysed microarray data	analysed microarray data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4365034	25599992	MBC	2	conceived and designed the investigation|carried out proteomic and molecular biology experiments|wrote the manuscript with input from all other authors	conceived and designed the investigation	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
4365034	25599992	MBC	2	conceived and designed the investigation|carried out proteomic and molecular biology experiments|wrote the manuscript with input from all other authors	carried out proteomic and molecular biology experiments	Performed the experiments	Investigation	YES
4365034	25599992	MBC	2	conceived and designed the investigation|carried out proteomic and molecular biology experiments|wrote the manuscript with input from all other authors	wrote the manuscript with input from all other authors	Wrote the paper	Writing - Original Draft	YES
4365034	25599992	MH	2	carried out iclip experiments	carried out iclip experiments	Performed the experiments	Investigation	YES
4365034	25599992	MK	2	analysed microarray data	analysed microarray data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5309194	28197984	All	2	data is shown in graphs	data is shown in graphs	-	-	NO
5309194	28197984	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5309194	28197984	Dong-Ju Kims	2	insightful suggestions	insightful suggestions	-	-	NO
5309194	28197984	JW	2	participated in the design of the study, and supervised the research work	participated in the design of the study, and supervised the research work	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Supervision	YES
5309194	28197984	KS	2	helped to review and to edit the manuscript	helped to review and to edit the manuscript	Wrote the paper	Writing - Review & Editing	YES
5309194	28197984	NC	2	carried out the transport experiments, participated in the reference research and drafted the manuscript	carried out the transport experiments, participated in the reference research and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5309194	28197984	SG	2	carried out the surface potential analysis	carried out the surface potential analysis	Performed the experiments	Investigation	YES
5309194	28197984	SJ	2	conceived of the study, and participated in its design and coordination and helped to draft the manuscript	conceived of the study, and participated in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
5309194	28197984	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5668983	29096605	LZ	2	conceived and designed the study|were responsible for data analysis and revising the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5668983	29096605	LZ	2	conceived and designed the study|were responsible for data analysis and revising the manuscript	were responsible for data analysis and revising the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5668983	29096605	MZ	2	were responsible for data analysis and revising the manuscript	were responsible for data analysis and revising the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5668983	29096605	NS	2	conceived and designed the study|wrote the manuscript|were responsible for data analysis and revising the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5668983	29096605	NS	2	conceived and designed the study|wrote the manuscript|were responsible for data analysis and revising the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5668983	29096605	NS	2	conceived and designed the study|wrote the manuscript|were responsible for data analysis and revising the manuscript	were responsible for data analysis and revising the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5758590	29354139	CL	7	performed the sampling|measured the contents of mycotoxins and performed quantitative real-time pcr analysis|performed nmr measurements, spectral processing and data analysis|wrote the article	performed the sampling	Performed the experiments	Investigation	YES
5758590	29354139	CL	7	performed the sampling|measured the contents of mycotoxins and performed quantitative real-time pcr analysis|performed nmr measurements, spectral processing and data analysis|wrote the article	measured the contents of mycotoxins and performed quantitative real-time pcr analysis	Performed the experiments	Investigation	YES
5758590	29354139	CL	7	performed the sampling|measured the contents of mycotoxins and performed quantitative real-time pcr analysis|performed nmr measurements, spectral processing and data analysis|wrote the article	performed nmr measurements, spectral processing and data analysis	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5758590	29354139	CL	7	performed the sampling|measured the contents of mycotoxins and performed quantitative real-time pcr analysis|performed nmr measurements, spectral processing and data analysis|wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
5758590	29354139	FC	7	performed the sampling|measured the contents of mycotoxins and performed quantitative real-time pcr analysis|performed nmr measurements, spectral processing and data analysis|wrote the article	performed the sampling	Performed the experiments	Investigation	YES
5758590	29354139	FC	7	performed the sampling|measured the contents of mycotoxins and performed quantitative real-time pcr analysis|performed nmr measurements, spectral processing and data analysis|wrote the article	measured the contents of mycotoxins and performed quantitative real-time pcr analysis	Performed the experiments	Investigation	YES
5758590	29354139	FC	7	performed the sampling|measured the contents of mycotoxins and performed quantitative real-time pcr analysis|performed nmr measurements, spectral processing and data analysis|wrote the article	performed nmr measurements, spectral processing and data analysis	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5758590	29354139	FC	7	performed the sampling|measured the contents of mycotoxins and performed quantitative real-time pcr analysis|performed nmr measurements, spectral processing and data analysis|wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
5758590	29354139	H-PL	7	involved in the manuscript refinement	involved in the manuscript refinement	-	-	NO
5758590	29354139	HL	7	involved in the manuscript refinement	involved in the manuscript refinement	-	-	NO
5758590	29354139	HT	7	designed the project|wrote the article	designed the project	Conceived and designed the experiments	Methodology	YES
5758590	29354139	HT	7	designed the project|wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
5758590	29354139	JZ	7	performed the sampling|performed nmr measurements, spectral processing and data analysis	performed the sampling	Performed the experiments	Investigation	YES
5758590	29354139	JZ	7	performed the sampling|performed nmr measurements, spectral processing and data analysis	performed nmr measurements, spectral processing and data analysis	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5758590	29354139	Y-CL	7	designed the project|wrote the article	designed the project	Conceived and designed the experiments	Methodology	YES
5758590	29354139	Y-CL	7	designed the project|wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
4415804	25928886	FPDC	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415804	25928886	JDW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415804	25928886	JDW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415804	25928886	JDW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415804	25928886	JDW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415804	25928886	UKS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415804	25928886	UKS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415804	25928886	UKS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415804	25928886	UKS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1933600	17684569	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1933600	17684569	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1933600	17684569	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1933600	17684569	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1933600	17684569	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1933600	17684569	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1933600	17684569	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1933600	17684569	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1933600	17684569	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1933600	17684569	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4940907	27408608	GH	2	developed the idea for this systematic review|prepared the protocol|prepared the first draft of the manuscript	developed the idea for this systematic review	Conceived and designed the experiments|Performed the experiments	Conceptualization|Methodology	YES
4940907	27408608	GH	2	developed the idea for this systematic review|prepared the protocol|prepared the first draft of the manuscript	prepared the protocol	Conceived and designed the experiments	Methodology	YES
4940907	27408608	GH	2	developed the idea for this systematic review|prepared the protocol|prepared the first draft of the manuscript	prepared the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
4940907	27408608	LS	2	developed the idea for this systematic review|while data extraction, analyses, and synthesis was done by all authors	developed the idea for this systematic review	Conceived and designed the experiments|Performed the experiments	Conceptualization|Methodology	YES
4940907	27408608	LS	2	developed the idea for this systematic review|while data extraction, analyses, and synthesis was done by all authors	while data extraction, analyses, and synthesis was done by all authors	Analyzed the data	Data curation|Formal analysis	YES
4940907	27408608	MP	2	while data extraction, analyses, and synthesis was done by all authors	while data extraction, analyses, and synthesis was done by all authors	Analyzed the data	Data curation|Formal analysis	YES
4940907	27408608	PCC	2	acquired part of the data	acquired part of the data	Performed the experiments	Investigation	YES
4940907	27408608	all authors	2	read and approved of the final manuscript	read and approved of the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4388601	25712476	AE	2	performed the experiments in mammalian cell culture	performed the experiments in mammalian cell culture	Performed the experiments	Investigation	YES
4388601	25712476	BJT	2	supervised the experiments|performed the initial genetic screen, conceived the experiments and wrote the manuscript with input from the other authors	supervised the experiments	-	Supervision	YES
4388601	25712476	BJT	2	supervised the experiments|performed the initial genetic screen, conceived the experiments and wrote the manuscript with input from the other authors	performed the initial genetic screen, conceived the experiments and wrote the manuscript with input from the other authors	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
4388601	25712476	GCF	2	performed the experiments in drosophila	performed the experiments in drosophila	Performed the experiments	Investigation	YES
4388601	25712476	IK	2	performed the experiments in drosophila	performed the experiments in drosophila	Performed the experiments	Investigation	YES
4388601	25712476	NT	2	supervised the experiments	supervised the experiments	-	Supervision	YES
4388601	25712476	PSR	2	performed the biochemical experiments	performed the biochemical experiments	Performed the experiments	Investigation	YES
5311015	28205102	All	PLoS52	data were included in the main manuscript	data were included in the main manuscript	-	-	NO
5311015	28205102	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5311015	28205102	JA	PLoS52	analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
5311015	28205102	NAY	PLoS52	conceived of the study|designed experiments	conceived of the study	Conceived and designed the experiments	Conceptualization	YES
5311015	28205102	NAY	PLoS52	conceived of the study|designed experiments	designed experiments	Conceived and designed the experiments	Methodology	YES
5311015	28205102	NN	PLoS52	performed experiments|analysed the data|wrote the manuscript	performed experiments	Performed the experiments	Investigation	YES
5311015	28205102	NN	PLoS52	performed experiments|analysed the data|wrote the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
5311015	28205102	NN	PLoS52	performed experiments|analysed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5311015	28205102	RH	PLoS52	conceived of the study|designed experiments|analysed the data|wrote the manuscript	conceived of the study	Conceived and designed the experiments	Conceptualization	YES
5311015	28205102	RH	PLoS52	conceived of the study|designed experiments|analysed the data|wrote the manuscript	designed experiments	Conceived and designed the experiments	Methodology	YES
5311015	28205102	RH	PLoS52	conceived of the study|designed experiments|analysed the data|wrote the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
5311015	28205102	RH	PLoS52	conceived of the study|designed experiments|analysed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5311015	28205102	SR	PLoS52	designed experiments	designed experiments	Conceived and designed the experiments	Methodology	YES
5311015	28205102	The authors	PLoS52	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
1933601	17684570	BP	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1933601	17684570	BP	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1933601	17684570	JB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1933601	17684570	KS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1933601	17684570	KS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1933601	17684570	KS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1933601	17684570	WZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1933601	17684570	WZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1933601	17684570	WZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1933601	17684570	WZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1933601	17684570	XA	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5669012	29096600	All Authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5669012	29096600	All authors	2	contributed comments to the final version of the manuscript	contributed comments to the final version of the manuscript	-	-	NO
5669012	29096600	DZ	2	contributed custom-made software and codes, and participated in sample collection, data analysis and data visualisation	contributed custom-made software and codes, and participated in sample collection, data analysis and data visualisation	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Formal analysis|Investigation|Resources|Software|Visualization	YES
5669012	29096600	GTW	2	conceived and coordinated the study, and reviewed the manuscript	conceived and coordinated the study, and reviewed the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Project administration|Writing - Review & Editing	YES
5669012	29096600	IJ	2	participated in the design of the study, data analysis, data visualisation, and co-wrote the manuscript	participated in the design of the study, data analysis, data visualisation, and co-wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Visualization|Writing - Original Draft	YES
5669012	29096600	JZ	2	participated in the design of the study and in the molecular lab work	participated in the design of the study and in the molecular lab work	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5669012	29096600	RC	2	participated in the molecular lab work, data analysis, and carried out sequence alignments	participated in the molecular lab work, data analysis, and carried out sequence alignments	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5669012	29096600	WXL	2	conceived and coordinated the study, and reviewed the manuscript	conceived and coordinated the study, and reviewed the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Project administration|Writing - Review & Editing	YES
5669012	29096600	ZH	2	collected the samples, participated in the design of the study, lab work, data analysis, and helped write the manuscript	collected the samples, participated in the design of the study, lab work, data analysis, and helped write the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5758593	29354137	AD	2	provided the tetraploid sequence of btr1 btr2 orthologs|wrote the manuscript	provided the tetraploid sequence of btr1 btr2 orthologs	Performed the experiments	Investigation	YES
5758593	29354137	AD	2	provided the tetraploid sequence of btr1 btr2 orthologs|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5758593	29354137	All authors	2	have reviewed and commented on the manuscript	have reviewed and commented on the manuscript	Wrote the paper	Writing - Review & Editing	YES
5758593	29354137	BK	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5758593	29354137	FD	2	carried out haplotype analysis	carried out haplotype analysis	Performed the experiments	Investigation	YES
5758593	29354137	GW	2	provided the archaeobotanical data|wrote the manuscript	provided the archaeobotanical data	Contributed reagents/materials/analysis tools	Resources	YES
5758593	29354137	GW	2	provided the archaeobotanical data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5758593	29354137	MP	2	assessed rachis type and performed qtl analysis|carried out haplotype analysis|designed the experiments|wrote the manuscript	assessed rachis type and performed qtl analysis	Performed the experiments	Investigation	YES
5758593	29354137	MP	2	assessed rachis type and performed qtl analysis|carried out haplotype analysis|designed the experiments|wrote the manuscript	carried out haplotype analysis	Performed the experiments	Investigation	YES
5758593	29354137	MP	2	assessed rachis type and performed qtl analysis|carried out haplotype analysis|designed the experiments|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5758593	29354137	MP	2	assessed rachis type and performed qtl analysis|carried out haplotype analysis|designed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5758593	29354137	SS	2	assessed rachis type and performed qtl analysis	assessed rachis type and performed qtl analysis	Performed the experiments	Investigation	YES
5758593	29354137	TKo	2	designed the experiments|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5758593	29354137	TKo	2	designed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4474527	25899817	FP	2	was edited by all other authors	was edited by all other authors	Wrote the paper	Writing - Review & Editing	YES
4474527	25899817	SPJ	2	was edited by all other authors	was edited by all other authors	Wrote the paper	Writing - Review & Editing	YES
4944315	27418883	CKC	2	conception and design of research|interpreted results of research|drafted the manuscript|edited and revised the manuscript|approved final version of manuscript	conception and design of research	Conceived and designed the experiments	Conceptualization|Methodology	YES
4944315	27418883	CKC	2	conception and design of research|interpreted results of research|drafted the manuscript|edited and revised the manuscript|approved final version of manuscript	interpreted results of research	Analyzed the data	Formal analysis	YES
4944315	27418883	CKC	2	conception and design of research|interpreted results of research|drafted the manuscript|edited and revised the manuscript|approved final version of manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4944315	27418883	CKC	2	conception and design of research|interpreted results of research|drafted the manuscript|edited and revised the manuscript|approved final version of manuscript	edited and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4944315	27418883	CKC	2	conception and design of research|interpreted results of research|drafted the manuscript|edited and revised the manuscript|approved final version of manuscript	approved final version of manuscript	-	-	NO
4944315	27418883	CYC	2	performed experiments|conception and design of research|analyzed data|interpreted results of research|edited and revised the manuscript	performed experiments	Performed the experiments	Investigation	YES
4944315	27418883	CYC	2	performed experiments|conception and design of research|analyzed data|interpreted results of research|edited and revised the manuscript	conception and design of research	Conceived and designed the experiments	Conceptualization|Methodology	YES
4944315	27418883	CYC	2	performed experiments|conception and design of research|analyzed data|interpreted results of research|edited and revised the manuscript	analyzed data	Analyzed the data	Formal analysis	YES
4944315	27418883	CYC	2	performed experiments|conception and design of research|analyzed data|interpreted results of research|edited and revised the manuscript	interpreted results of research	Analyzed the data	Formal analysis	YES
4944315	27418883	CYC	2	performed experiments|conception and design of research|analyzed data|interpreted results of research|edited and revised the manuscript	edited and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4944315	27418883	HJW	2	conception and design of research|edited and revised the manuscript	conception and design of research	Conceived and designed the experiments	Conceptualization|Methodology	YES
4944315	27418883	HJW	2	conception and design of research|edited and revised the manuscript	edited and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4944315	27418883	IFC	2	performed experiments|analyzed data	performed experiments	Performed the experiments	Investigation	YES
4944315	27418883	IFC	2	performed experiments|analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
4944315	27418883	KMC	2	conception and design of research|interpreted results of research	conception and design of research	Conceived and designed the experiments	Conceptualization|Methodology	YES
4944315	27418883	KMC	2	conception and design of research|interpreted results of research	interpreted results of research	Analyzed the data	Formal analysis	YES
1933602	17684561	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1933602	17684561	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1933602	17684561	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1933602	17684561	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1933602	17684561	KW	PLoS5	Conceived and designed the experiments|Contributed to editing the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1933602	17684561	KW	PLoS5	Conceived and designed the experiments|Contributed to editing the manuscript	Contributed to editing the manuscript	Wrote the paper	Writing - Review & Editing	YES
1933602	17684561	TH	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1933602	17684561	TH	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1933602	17684561	TH	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5758599	29354142	DC	PLoS52	designed the research|supervised the experiments|wrote the article	designed the research	Conceived and designed the experiments	Methodology	YES
5758599	29354142	DC	PLoS52	designed the research|supervised the experiments|wrote the article	supervised the experiments	-	Supervision	YES
5758599	29354142	DC	PLoS52	designed the research|supervised the experiments|wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
5758599	29354142	ML	PLoS52	performed the research|wrote the article	performed the research	Performed the experiments	Investigation	YES
5758599	29354142	ML	PLoS52	performed the research|wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
5758599	29354142	SM	PLoS52	designed the research|supervised the experiments|wrote the article	designed the research	Conceived and designed the experiments	Methodology	YES
5758599	29354142	SM	PLoS52	designed the research|supervised the experiments|wrote the article	supervised the experiments	-	Supervision	YES
5758599	29354142	SM	PLoS52	designed the research|supervised the experiments|wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
5758599	29354142	ZM	PLoS52	designed the research|performed the research|analyzed the data|wrote the article	designed the research	Conceived and designed the experiments	Methodology	YES
5758599	29354142	ZM	PLoS52	designed the research|performed the research|analyzed the data|wrote the article	performed the research	Performed the experiments	Investigation	YES
5758599	29354142	ZM	PLoS52	designed the research|performed the research|analyzed the data|wrote the article	analyzed the data	Analyzed the data	Formal analysis	YES
5758599	29354142	ZM	PLoS52	designed the research|performed the research|analyzed the data|wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
5311017	28205101	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5311017	28205101	DX	2	performed the research, analyzed data and wrote this manuscript	performed the research, analyzed data and wrote this manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5311017	28205101	JN	2	designed the research and polished the manuscript	designed the research and polished the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5311017	28205101	QC	2	helped to draft the manuscript	helped to draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5311017	28205101	SL	2	designed the research and polished the manuscript	designed the research and polished the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
4415806	25927921	CB	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415806	25927921	CB	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415806	25927921	GB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415806	25927921	GB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415806	25927921	GB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415806	25927921	GB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415806	25927921	JH	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415806	25927921	JH	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415806	25927921	RDR	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415806	25927921	RDR	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5670726	29100491	JK	2	coordinated the study and helped finalize the manuscript	coordinated the study and helped finalize the manuscript	Wrote the paper	Project administration|Writing - Review & Editing	YES
5670726	29100491	LFB	2	performed experimental procedure and the complete data analysis of the present study|prepared a draft of the manuscript	performed experimental procedure and the complete data analysis of the present study	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5670726	29100491	LFB	2	performed experimental procedure and the complete data analysis of the present study|prepared a draft of the manuscript	prepared a draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
5670726	29100491	MI	2	performed experimental procedure and the complete data analysis of the present study	performed experimental procedure and the complete data analysis of the present study	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5670726	29100491	VFW	2	coordinated the study and helped finalize the manuscript	coordinated the study and helped finalize the manuscript	Wrote the paper	Project administration|Writing - Review & Editing	YES
4474532	25925385	MMUA	2	conceived and supervised project, analyzed data, and wrote manuscript	conceived and supervised project, analyzed data, and wrote manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Supervision|Writing - Original Draft	YES
4474532	25925385	PERK	2	collected data, solved and refined structures, preformed biochemical experiments, and analyzed data and structures	collected data, solved and refined structures, preformed biochemical experiments, and analyzed data and structures	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4474532	25925385	PRN	2	preformed in vivo phosphorylation experiments	preformed in vivo phosphorylation experiments	Performed the experiments	Investigation	YES
3859205	24376378	Carla Jones	PLoS52	evaluated inos expression	evaluated inos expression	Performed the experiments	Investigation	YES
3859205	24376378	Fernando Queiroz Cunha	PLoS52	supervised the study, critically reviewed the paper and provided essential reagents	supervised the study, critically reviewed the paper and provided essential reagents	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Supervision|Writing - Review & Editing	YES
3859205	24376378	Ignez Gaspar-Elsas	PLoS52	supervised the study, critically reviewed the paper and provided essential reagents	supervised the study, critically reviewed the paper and provided essential reagents	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Supervision|Writing - Review & Editing	YES
3859205	24376378	Maria Augusta Arruda	PLoS52	designed the inhibitor studies	designed the inhibitor studies	Conceived and designed the experiments	Methodology	YES
3859205	24376378	P. Xavier-Elsas	PLoS52	made equally essential contributions to the execution and design of the experiments, respectively, and should therefore be considered joint first authors, listed in alphabetical order	made equally essential contributions to the execution and design of the experiments, respectively, and should therefore be considered joint first authors, listed in alphabetical order	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3859205	24376378	Pedro Xavier-Elsas	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3859205	24376378	Ricardo A. Luz	PLoS52	evaluated no production	evaluated no production	-	-	NO
3859205	24376378	Thiago Mattar Cunha	PLoS52	designed the inhibitor studies	designed the inhibitor studies	Conceived and designed the experiments	Methodology	YES
4947244	27429596	BC	4	This study was designed by|data analysis was conducted by|manuscript preparation was conducted by	This study was designed by	Conceived and designed the experiments	Methodology	YES
4947244	27429596	BC	4	This study was designed by|data analysis was conducted by|manuscript preparation was conducted by	data analysis was conducted by	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4947244	27429596	BC	4	This study was designed by|data analysis was conducted by|manuscript preparation was conducted by	manuscript preparation was conducted by	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4947244	27429596	LB	4	data were collected by	data were collected by	Performed the experiments	Investigation	YES
4947244	27429596	MF	4	data were collected by|manuscript preparation was conducted by	data were collected by	Performed the experiments	Investigation	YES
4947244	27429596	MF	4	data were collected by|manuscript preparation was conducted by	manuscript preparation was conducted by	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4947244	27429596	NM	4	This study was designed by|data analysis was conducted by|manuscript preparation was conducted by	This study was designed by	Conceived and designed the experiments	Methodology	YES
4947244	27429596	NM	4	This study was designed by|data analysis was conducted by|manuscript preparation was conducted by	data analysis was conducted by	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4947244	27429596	NM	4	This study was designed by|data analysis was conducted by|manuscript preparation was conducted by	manuscript preparation was conducted by	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4947244	27429596	RC	4	data were collected by	data were collected by	Performed the experiments	Investigation	YES
1933603	17684551	GB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1933603	17684551	GB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1933603	17684551	GB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1933603	17684551	GB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1933603	17684551	GM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1933603	17684551	GM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1933603	17684551	GM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1933603	17684551	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1933603	17684551	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1933603	17684551	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1933603	17684551	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1933603	17684551	TH	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1933603	17684551	TH	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5758602	29354143	All authors	2	discussed the results and commented on the manuscript	discussed the results and commented on the manuscript	-	-	NO
5758602	29354143	BG	2	analyzed insect bioassay data	analyzed insect bioassay data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5758602	29354143	CS	2	analyzed molecular biology data	analyzed molecular biology data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5758602	29354143	KD	2	analyzed molecular biology data|edited the manuscript	analyzed molecular biology data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5758602	29354143	KD	2	analyzed molecular biology data|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5758602	29354143	PS	2	analyzed molecular biology data	analyzed molecular biology data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5758602	29354143	SD	2	edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5758602	29354143	SM	2	analyzed molecular biology data|analyzed insect bioassay data|wrote the manuscript	analyzed molecular biology data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5758602	29354143	SM	2	analyzed molecular biology data|analyzed insect bioassay data|wrote the manuscript	analyzed insect bioassay data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5758602	29354143	SM	2	analyzed molecular biology data|analyzed insect bioassay data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5758602	29354143	SS	2	analyzed insect bioassay data|wrote the manuscript	analyzed insect bioassay data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5758602	29354143	SS	2	analyzed insect bioassay data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4619873	26539529	Constantinos Giaginis	2	contributed equally to the study	contributed equally to the study	-	-	NO
4619873	26539529	Eleftheria Lakiotaki	2	contributed equally to the study	contributed equally to the study	-	-	NO
4415807	25927685	ALP	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415807	25927685	ST	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415807	25927685	ST	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415807	25927685	ST	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415807	25927685	ST	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415807	25927685	ST	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415807	25927685	TCN	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415807	25927685	TCN	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415807	25927685	TCN	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5674736	29110701	F.L.	PLoS52	designed the project|wrote the paper	designed the project	Conceived and designed the experiments	Methodology	YES
5674736	29110701	F.L.	PLoS52	designed the project|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5674736	29110701	K.H.	PLoS52	did the pcr validation experiment	did the pcr validation experiment	Performed the experiments	Investigation|Validation	YES
5674736	29110701	M.J.	PLoS52	designed the project|analyzed the data|wrote the paper	designed the project	Conceived and designed the experiments	Methodology	YES
5674736	29110701	M.J.	PLoS52	designed the project|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5674736	29110701	M.J.	PLoS52	designed the project|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5674736	29110701	S.D.	PLoS52	carried out ssr identification and analysis|made the figures|drafted the manuscript|analyzed the data	carried out ssr identification and analysis	Performed the experiments	Investigation	YES
5674736	29110701	S.D.	PLoS52	carried out ssr identification and analysis|made the figures|drafted the manuscript|analyzed the data	made the figures	-	Visualization	YES
5674736	29110701	S.D.	PLoS52	carried out ssr identification and analysis|made the figures|drafted the manuscript|analyzed the data	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5674736	29110701	S.D.	PLoS52	carried out ssr identification and analysis|made the figures|drafted the manuscript|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5674736	29110701	S.W.	PLoS52	distinguished fruit fries|wrote the paper	distinguished fruit fries	-	-	NO
5674736	29110701	S.W.	PLoS52	distinguished fruit fries|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5313495	28211005	ERH	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
5313495	28211005	ERH	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5313495	28211005	HP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5313495	28211005	JC	PLoS5	Bio sequencing and sequence analysis	Bio sequencing and sequence analysis	Performed the experiments	Investigation	YES
5313495	28211005	JGF	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5313495	28211005	LEM	PLoS5	Generated and analyzed the data|Wrote the paper	Generated and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5313495	28211005	LEM	PLoS5	Generated and analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5313495	28211005	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Generated and analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5313495	28211005	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Generated and analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
5313495	28211005	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Generated and analyzed the data|Wrote the paper	Generated and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5313495	28211005	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Generated and analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5313495	28211005	MJB	PLoS5	Bio sequencing and sequence analysis	Bio sequencing and sequence analysis	Performed the experiments	Investigation	YES
5313495	28211005	NS	PLoS5	Project management	Project management	-	Project administration	YES
5313495	28211005	RK	PLoS5	Bio library prep	Bio library prep	-	-	NO
5313495	28211005	TW	PLoS5	Project management	Project management	-	Project administration	YES
4962429	27468258	AEJ	2	performed all emg procedures and analyses	performed all emg procedures and analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4962429	27468258	AEM	2	performed data collection	performed data collection	Performed the experiments	Investigation	YES
4962429	27468258	AMH	2	performed data collection	performed data collection	Performed the experiments	Investigation	YES
4962429	27468258	CBM	2	performed data collection	performed data collection	Performed the experiments	Investigation	YES
4962429	27468258	GDO	2	performed all emg procedures and analyses	performed all emg procedures and analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4962429	27468258	JJM	2	assisted study design, data analyses and the drafting of the manuscript	assisted study design, data analyses and the drafting of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4962429	27468258	JJS	2	performed data collection	performed data collection	Performed the experiments	Investigation	YES
4962429	27468258	KCY	2	assisted study design, data analyses and the drafting of the manuscript	assisted study design, data analyses and the drafting of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4962429	27468258	MDR	2	drafted the first version of the manuscript	drafted the first version of the manuscript	Wrote the paper	Writing - Original Draft	YES
4962429	27468258	PWM	2	coordinated the study, recruited participants, and analyzed the data|performed data collection	coordinated the study, recruited participants, and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Project administration	YES
4962429	27468258	PWM	2	coordinated the study, recruited participants, and analyzed the data|performed data collection	performed data collection	Performed the experiments	Investigation	YES
4962429	27468258	WCK	2	coordinated the study, recruited participants, and analyzed the data|performed data collection|drafted the first version of the manuscript	coordinated the study, recruited participants, and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Project administration	YES
4962429	27468258	WCK	2	coordinated the study, recruited participants, and analyzed the data|performed data collection|drafted the first version of the manuscript	performed data collection	Performed the experiments	Investigation	YES
4962429	27468258	WCK	2	coordinated the study, recruited participants, and analyzed the data|performed data collection|drafted the first version of the manuscript	drafted the first version of the manuscript	Wrote the paper	Writing - Original Draft	YES
4962429	27468258	WHW	2	performed all emg procedures and analyses	performed all emg procedures and analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
1933604	17684563	HB	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1933604	17684563	HP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1933604	17684563	HP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1933604	17684563	HP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1933604	17684563	HP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1933604	17684563	JB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1933604	17684563	JB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1933604	17684563	JB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1933604	17684563	MR	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1933604	17684563	MR	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1933604	17684563	PM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1933604	17684563	PM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5758603	29354153	AH	2	provided intellectual input and revised the manuscript	provided intellectual input and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5758603	29354153	MG	2	provided intellectual input and revised the manuscript	provided intellectual input and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5758603	29354153	RG	2	performed experiments and drafted the manuscript	performed experiments and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5758603	29354153	YW	2	conduced rna seq analysis	conduced rna seq analysis	Performed the experiments	Investigation	YES
5674791	29115920	DPW	2	assisted with analysis of the data or organization of the manuscript	assisted with analysis of the data or organization of the manuscript	Analyzed the data	Formal analysis	YES
5674791	29115920	TASSEL	2	pipeline for soybean snp calling	pipeline for soybean snp calling	-	-	NO
5315648	28213885	AC	2	conceptualized and supervised entire work, compiled data and finalized the manuscript	conceptualized and supervised entire work, compiled data and finalized the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Data curation|Supervision|Writing - Review & Editing	YES
5315648	28213885	AM	2	carried out most of the experiments and wrote the manuscript	carried out most of the experiments and wrote the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5315648	28213885	APG	2	supervised lcms/quantification work	supervised lcms/quantification work	-	Supervision	YES
5315648	28213885	All	2	the data is available	the data is available	-	-	NO
5315648	28213885	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5315648	28213885	BAS	2	supervised chemistry work and structure elucidation	supervised chemistry work and structure elucidation	-	Supervision	YES
5315648	28213885	CR	2	performed experiments at fermenter scale	performed experiments at fermenter scale	Performed the experiments	Investigation	YES
5315648	28213885	CSIR-IIIM	2	for his interest in this work	for his interest in this work	-	-	NO
5315648	28213885	FYP	2	is gratefully acknowledged	is gratefully acknowledged	-	-	NO
5315648	28213885	MK	2	isolated and characterized compounds|did lcms analysis and quantification	isolated and characterized compounds	Performed the experiments	Investigation	YES
5315648	28213885	MK	2	isolated and characterized compounds|did lcms analysis and quantification	did lcms analysis and quantification	-	-	NO
5315648	28213885	PA	2	helped in molecular work	helped in molecular work	Performed the experiments	Investigation	YES
5315648	28213885	Project Plant-Microbe	2	is gratefully acknowledged	is gratefully acknowledged	-	-	NO
5315648	28213885	SGG	2	designed and supervised molecular work	designed and supervised molecular work	Conceived and designed the experiments|Performed the experiments	Investigation|Supervision	YES
5315648	28213885	Soil Interactions	2	is gratefully acknowledged	is gratefully acknowledged	-	-	NO
5315648	28213885	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
1934337	17684548	AT	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper|Designed the model|Analyzed the model|Performed computer simulations	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1934337	17684548	AT	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper|Designed the model|Analyzed the model|Performed computer simulations	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1934337	17684548	AT	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper|Designed the model|Analyzed the model|Performed computer simulations	Designed the model	Conceived and designed the experiments|Performed the experiments	Methodology	YES
1934337	17684548	AT	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper|Designed the model|Analyzed the model|Performed computer simulations	Analyzed the model	Performed the experiments|Analyzed the data	Formal analysis|Methodology	YES
1934337	17684548	AT	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper|Designed the model|Analyzed the model|Performed computer simulations	Performed computer simulations	Performed the experiments	Formal analysis|Investigation	YES
1934337	17684548	JW	PLoS5	Wrote the paper|Designed the model	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1934337	17684548	JW	PLoS5	Wrote the paper|Designed the model	Designed the model	Conceived and designed the experiments|Performed the experiments	Methodology	YES
1934337	17684548	MF	PLoS5	Wrote the paper|Performed computer simulations	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1934337	17684548	MF	PLoS5	Wrote the paper|Performed computer simulations	Performed computer simulations	Performed the experiments	Formal analysis|Investigation	YES
1934337	17684548	PH	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1934337	17684548	YK	PLoS5	Analyzed the model	Analyzed the model	Performed the experiments|Analyzed the data	Formal analysis|Methodology	YES
4415808	25928296	AF	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415808	25928296	AF	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415808	25928296	CA	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4415808	25928296	CA	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4415808	25928296	JP	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415808	25928296	OK	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4415808	25928296	OK	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4415808	25928296	SNU	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415808	25928296	SNU	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415808	25928296	SNU	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415808	25928296	SV	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4415808	25928296	SV	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4415808	25928296	UD	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4966593	27478425	BL	2	formulated the research question, designed the study, carried it out, analysed the data and revised the manuscript	formulated the research question, designed the study, carried it out, analysed the data and revised the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Review & Editing	YES
4966593	27478425	CGS	2	formulated the research question, designed the study, carried it out, and revised the manuscript	formulated the research question, designed the study, carried it out, and revised the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Writing - Review & Editing	YES
4966593	27478425	CP	2	designed the study, carried it out, analysed the data and revised the manuscript	designed the study, carried it out, analysed the data and revised the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Review & Editing	YES
4966593	27478425	FA	2	formulated the research question, designed the study, carried it out, analysed the data and revised the manuscript	formulated the research question, designed the study, carried it out, analysed the data and revised the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Review & Editing	YES
4966593	27478425	JDC	2	formulated the research question, designed the study, carried it out, analysed the data and wrote the manuscript	formulated the research question, designed the study, carried it out, analysed the data and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4966593	27478425	JJS	2	formulated the research question, designed the study, carried it out, analysed the data and revised the manuscript	formulated the research question, designed the study, carried it out, analysed the data and revised the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Review & Editing	YES
5758608	29354141	MO	2	designed this review work, assembled and analyzed the related papers, performed the experiments, and wrote the manuscript	designed this review work, assembled and analyzed the related papers, performed the experiments, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
3859213	24376383	Jose M. Alvarez	2	contributed equally to this work	contributed equally to this work	-	-	NO
3859213	24376383	Ricardo J. Ordas	2	contributed equally to this work	contributed equally to this work	-	-	NO
4415809	25928138	DCW	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4415809	25928138	DCW	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4415809	25928138	DCW	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415809	25928138	PJD	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415809	25928138	WL	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415809	25928138	WL	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4516428	25872774	AG	2	were responsible for overall supervision|wrote the manuscript	were responsible for overall supervision	-	Supervision	YES
4516428	25872774	AG	2	were responsible for overall supervision|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4516428	25872774	AJM	2	designed experiments and analysed data|wrote the manuscript	designed experiments and analysed data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
4516428	25872774	AJM	2	designed experiments and analysed data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4516428	25872774	CCC	2	performed lysosomal-current experiments	performed lysosomal-current experiments	Performed the experiments	Investigation	YES
4516428	25872774	CGr	2	performed lysosomal-current experiments	performed lysosomal-current experiments	Performed the experiments	Investigation	YES
4516428	25872774	CWS	2	performed lysosomal-current experiments	performed lysosomal-current experiments	Performed the experiments	Investigation	YES
4516428	25872774	FMP	2	supervised macrophage work	supervised macrophage work	-	Supervision	YES
4516428	25872774	JP	2	were responsible for overall supervision|wrote the manuscript	were responsible for overall supervision	-	Supervision	YES
4516428	25872774	JP	2	were responsible for overall supervision|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4516428	25872774	KTC	2	performed rt pcr and rt-qpcr experiments	performed rt pcr and rt-qpcr experiments	Performed the experiments	Investigation	YES
4516428	25872774	LCD	2	designed experiments and analysed data|wrote the manuscript	designed experiments and analysed data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
4516428	25872774	LCD	2	designed experiments and analysed data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4516428	25872774	MB	2	performed lysosomal-current experiments	performed lysosomal-current experiments	Performed the experiments	Investigation	YES
4516428	25872774	MEF	2	preparation, lentiviral expression and localization studies, immunoblotting, and radioligand binding assays	preparation, lentiviral expression and localization studies, immunoblotting, and radioligand binding assays	Performed the experiments	Investigation	YES
4516428	25872774	MR	2	designed experiments and analysed data|wrote the manuscript	designed experiments and analysed data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
4516428	25872774	MR	2	designed experiments and analysed data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4516428	25872774	NP	2	supervised macrophage work	supervised macrophage work	-	Supervision	YES
4516428	25872774	TFW	2	performed photoaffinity labelling	performed photoaffinity labelling	Performed the experiments	Investigation	YES
4516428	25872774	TP	2	designed experiments and analysed data	designed experiments and analysed data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
1934930	17684565	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1934930	17684565	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1934930	17684565	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1934930	17684565	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1934930	17684565	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4971637	27489522	All authors	2	have contributed to the conception and design of the study, generation, collection, assembly, analysis and/or interpretation of data|have drafted and approved the final version of the manuscript	have contributed to the conception and design of the study, generation, collection, assembly, analysis and/or interpretation of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Methodology|Resources	YES
4971637	27489522	All authors	2	have contributed to the conception and design of the study, generation, collection, assembly, analysis and/or interpretation of data|have drafted and approved the final version of the manuscript	have drafted and approved the final version of the manuscript	Wrote the paper	Writing - Original Draft	YES
5674806	29110697	ECT	PLoS52	conceived of this study|wrote, edited and approved the manuscript	conceived of this study	Conceived and designed the experiments	Conceptualization	YES
5674806	29110697	ECT	PLoS52	conceived of this study|wrote, edited and approved the manuscript	wrote, edited and approved the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5674806	29110697	ZH	PLoS52	conceived of this study|designed and wrote the pipeline|analyzed the data|wrote, edited and approved the manuscript	conceived of this study	Conceived and designed the experiments	Conceptualization	YES
5674806	29110697	ZH	PLoS52	conceived of this study|designed and wrote the pipeline|analyzed the data|wrote, edited and approved the manuscript	designed and wrote the pipeline	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
5674806	29110697	ZH	PLoS52	conceived of this study|designed and wrote the pipeline|analyzed the data|wrote, edited and approved the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5674806	29110697	ZH	PLoS52	conceived of this study|designed and wrote the pipeline|analyzed the data|wrote, edited and approved the manuscript	wrote, edited and approved the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5318318	28220445	All authors	2	reviewed the manuscript|read and approved the final manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5318318	28220445	All authors	2	reviewed the manuscript|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5318318	28220445	DT	2	conceived and designed the research	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5318318	28220445	JHW	2	conceived and designed the research|wrote the manuscript	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5318318	28220445	JHW	2	conceived and designed the research|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5318318	28220445	JJ	2	performed the in vivo experiment and analyzed the data	performed the in vivo experiment and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5318318	28220445	NY	2	performed the in vivo experiment and analyzed the data	performed the in vivo experiment and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5318318	28220445	RYM	2	conceived and designed the research|wrote the manuscript	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5318318	28220445	RYM	2	conceived and designed the research|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5318318	28220445	XJF	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5318318	28220445	XMW	2	performed the in vitro experiment	performed the in vitro experiment	Performed the experiments	Investigation	YES
5318318	28220445	XW	2	performed the in vitro experiment	performed the in vitro experiment	Performed the experiments	Investigation	YES
5318318	28220445	YH	2	performed the in vivo experiment and analyzed the data	performed the in vivo experiment and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4415810	25927439	ARA	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4415810	25927439	CR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415810	25927439	CR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4415810	25927439	CR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4415810	25927439	FM	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415810	25927439	FM	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415810	25927439	GD	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415810	25927439	KGM	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4415810	25927439	MM	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4415810	25927439	MM	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4415810	25927439	MS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415810	25927439	MS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415810	25927439	NJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415810	25927439	NJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415810	25927439	NJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415810	25927439	NJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415810	25927439	RP	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415810	25927439	US	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415810	25927439	US	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5759035	29354144	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5759035	29354144	RdS	2	helped with the created figures with the	helped with the created figures with the	-	Visualization	YES
5759035	29354144	The authors	2	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	Performed the experiments	Investigation	YES
1934931	17684566	CC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1934931	17684566	CC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1934931	17684566	CC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1934931	17684566	FS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1934931	17684566	FS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1934931	17684566	FS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1934931	17684566	KW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1934931	17684566	KW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1934931	17684566	KW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1934931	17684566	KW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1934931	17684566	RK	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1934931	17684566	RK	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4516432	25979828	BK	2	designed experiments|performed biochemical experiments|analyzed sequencing data|wrote the manuscript	designed experiments	Conceived and designed the experiments	Methodology	YES
4516432	25979828	BK	2	designed experiments|performed biochemical experiments|analyzed sequencing data|wrote the manuscript	performed biochemical experiments	Performed the experiments	Investigation	YES
4516432	25979828	BK	2	designed experiments|performed biochemical experiments|analyzed sequencing data|wrote the manuscript	analyzed sequencing data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4516432	25979828	BK	2	designed experiments|performed biochemical experiments|analyzed sequencing data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4516432	25979828	CJ	2	designed experiments|performed and analyzed single-molecule experiments|wrote the manuscript	designed experiments	Conceived and designed the experiments	Methodology	YES
4516432	25979828	CJ	2	designed experiments|performed and analyzed single-molecule experiments|wrote the manuscript	performed and analyzed single-molecule experiments	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4516432	25979828	CJ	2	designed experiments|performed and analyzed single-molecule experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4516432	25979828	DJP	2	prepared recombinant proteins	prepared recombinant proteins	Performed the experiments	Investigation	YES
4516432	25979828	DKS	2	prepared recombinant proteins	prepared recombinant proteins	Performed the experiments	Investigation	YES
4516432	25979828	HC	2	analyzed sequencing data|wrote the manuscript	analyzed sequencing data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4516432	25979828	HC	2	analyzed sequencing data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4516432	25979828	LL	2	designed experiments|performed and analyzed single-molecule experiments|wrote the manuscript	designed experiments	Conceived and designed the experiments	Methodology	YES
4516432	25979828	LL	2	designed experiments|performed and analyzed single-molecule experiments|wrote the manuscript	performed and analyzed single-molecule experiments	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4516432	25979828	LL	2	designed experiments|performed and analyzed single-molecule experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4516432	25979828	MF	2	performed and analyzed single-molecule experiments	performed and analyzed single-molecule experiments	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4516432	25979828	MH	2	designed experiments|performed biochemical experiments|wrote the manuscript	designed experiments	Conceived and designed the experiments	Methodology	YES
4516432	25979828	MH	2	designed experiments|performed biochemical experiments|wrote the manuscript	performed biochemical experiments	Performed the experiments	Investigation	YES
4516432	25979828	MH	2	designed experiments|performed biochemical experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4516432	25979828	SL	2	prepared recombinant proteins	prepared recombinant proteins	Performed the experiments	Investigation	YES
4516432	25979828	VNK	2	designed experiments|wrote the manuscript	designed experiments	Conceived and designed the experiments	Methodology	YES
4516432	25979828	VNK	2	designed experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5010764	27594812	GE	2	assisted in research design and consultation, sample analysis and manuscript preparation	assisted in research design and consultation, sample analysis and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5010764	27594812	MK	2	support of analysis instrument, sample analysis and manuscript preparation	support of analysis instrument, sample analysis and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5010764	27594812	NE	2	assisted in designing the study, writing the grant, study coordination, data collection, data analysis, and manuscript preparation	assisted in designing the study, writing the grant, study coordination, data collection, data analysis, and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Project administration|Writing - Original Draft	YES
4415811	25927436	AB	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4415811	25927436	AB	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4415811	25927436	EF	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4415811	25927436	NB	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415811	25927436	NB	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4415811	25927436	NB	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415811	25927436	NR	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415811	25927436	NR	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415811	25927436	NR	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415811	25927436	YL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415811	25927436	YL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415811	25927436	YL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415811	25927436	YL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415811	25927436	YL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415811	25927436	YMJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415811	25927436	YMJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415811	25927436	YMJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415811	25927436	YMJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5678558	29115936	JT	2	supervised and contributed to the drafting of the manuscript	supervised and contributed to the drafting of the manuscript	Wrote the paper	Supervision|Writing - Original Draft	YES
5678558	29115936	MD	2	conceived and performed experiments, interpreted the data, and developed the draft of the manuscript	conceived and performed experiments, interpreted the data, and developed the draft of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
5678558	29115936	MS	2	provided initial switchgrass clones|supervised and contributed to the drafting of the manuscript	provided initial switchgrass clones	Contributed reagents/materials/analysis tools	Resources	YES
5678558	29115936	MS	2	provided initial switchgrass clones|supervised and contributed to the drafting of the manuscript	supervised and contributed to the drafting of the manuscript	Wrote the paper	Supervision|Writing - Original Draft	YES
5678558	29115936	SX	2	performed bioinformatic analysis, interpreted the data, and contributed significantly in drafting the manuscript	performed bioinformatic analysis, interpreted the data, and contributed significantly in drafting the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5678558	29115936	VK	2	conceived, supervised the whole project, and contributed to the drafting and editing of the manuscript	conceived, supervised the whole project, and contributed to the drafting and editing of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
5319944	28224439	DM	1	Erythritol production and analysis	Erythritol production and analysis	-	-	NO
5319944	28224439	HI	1	Experiment planning and design|Erythritol production and analysis|Paper construction	Experiment planning and design	Conceived and designed the experiments	Methodology	YES
5319944	28224439	HI	1	Experiment planning and design|Erythritol production and analysis|Paper construction	Erythritol production and analysis	-	-	NO
5319944	28224439	HI	1	Experiment planning and design|Erythritol production and analysis|Paper construction	Paper construction	Performed the experiments	Investigation	YES
5319944	28224439	JO	1	Experiment planning and design|Paper construction	Experiment planning and design	Conceived and designed the experiments	Methodology	YES
5319944	28224439	JO	1	Experiment planning and design|Paper construction	Paper construction	Performed the experiments	Investigation	YES
5319944	28224439	KT	1	Experiment planning and design	Experiment planning and design	Conceived and designed the experiments	Methodology	YES
5319944	28224439	TK	1	Paper construction	Paper construction	Performed the experiments	Investigation	YES
5319944	28224439	TW	1	Experiment planning and design|Paper construction	Experiment planning and design	Conceived and designed the experiments	Methodology	YES
5319944	28224439	TW	1	Experiment planning and design|Paper construction	Paper construction	Performed the experiments	Investigation	YES
5024503	27651751	JLD	2	was responsible for animal training, animal testing, biochemical analyses, database management, and assistance with the study design and manuscript preparation	was responsible for animal training, animal testing, biochemical analyses, database management, and assistance with the study design and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Project administration|Software|Writing - Original Draft	YES
5024503	27651751	KKB	2	contributed to the study design, supervision of animal care and use, and interpretation of data	contributed to the study design, supervision of animal care and use, and interpretation of data	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Methodology|Resources|Supervision	YES
5024503	27651751	MvdM	2	were responsible for the study design and manuscript preparation	were responsible for the study design and manuscript preparation	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5024503	27651751	RJB	2	were responsible for the study design and manuscript preparation	were responsible for the study design and manuscript preparation	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5024503	27651751	RKB	2	contributed to study design, evaluation of intestinal functions, and manuscript preparation	contributed to study design, evaluation of intestinal functions, and manuscript preparation	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5024503	27651751	SLD	2	assisted with the biochemical analyses	assisted with the biochemical analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
1934932	17684567	J Li	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1934932	17684567	J Liu	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1934932	17684567	J Liu	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1934932	17684567	J Liu	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1934932	17684567	ME	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1934932	17684567	ME	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1934932	17684567	RK	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1934932	17684567	ZC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4551349	26136212	AK	2	performed most of the experiments	performed most of the experiments	Performed the experiments	Investigation	YES
4551349	26136212	DAC	2	were involved in conceptual design and manuscript authorship	were involved in conceptual design and manuscript authorship	Conceived and designed the experiments	Conceptualization	YES
4551349	26136212	GCP	2	performed most of the experiments|were involved in conceptual design and manuscript authorship	performed most of the experiments	Performed the experiments	Investigation	YES
4551349	26136212	GCP	2	performed most of the experiments|were involved in conceptual design and manuscript authorship	were involved in conceptual design and manuscript authorship	Conceived and designed the experiments	Conceptualization	YES
4551349	26136212	HRM	2	provided critical reagents and advice	provided critical reagents and advice	Contributed reagents/materials/analysis tools	Resources	YES
4551349	26136212	IF	2	provided critical reagents and advice	provided critical reagents and advice	Contributed reagents/materials/analysis tools	Resources	YES
4551349	26136212	JLH	2	analysed mass spectrometry data	analysed mass spectrometry data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4551349	26136212	LVS	2	performed most of the experiments|were involved in conceptual design and manuscript authorship	performed most of the experiments	Performed the experiments	Investigation	YES
4551349	26136212	LVS	2	performed most of the experiments|were involved in conceptual design and manuscript authorship	were involved in conceptual design and manuscript authorship	Conceived and designed the experiments	Conceptualization	YES
4551349	26136212	VHC	2	were involved in conceptual design and manuscript authorship	were involved in conceptual design and manuscript authorship	Conceived and designed the experiments	Conceptualization	YES
5760537	29354148	All authors	2	approved the final manuscript	approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5678747	29115927	AC	2	designed, conducted and described the statistical analysis as well as revised the manuscript	designed, conducted and described the statistical analysis as well as revised the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
5678747	29115927	MD	2	designed, conducted and described the statistical analysis as well as revised the manuscript	designed, conducted and described the statistical analysis as well as revised the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
5678747	29115927	PaS	2	designed the concept of the meta-analysis and wrote and revised the manuscript	designed the concept of the meta-analysis and wrote and revised the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5678747	29115927	PiS	2	collected, processed and analysed transcriptomic data and wrote the manuscript	collected, processed and analysed transcriptomic data and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Formal analysis|Investigation|Writing - Original Draft	YES
4232858	24460655	D Cappellini	2	served as investigators on this trial, enrolling patients|contributed to data interpretation, reviewed and provided their comments on this manuscript|served as study steering committee members overseeing the conduct of the trial, from study design to analysis plan and data interpretation	served as investigators on this trial, enrolling patients	Performed the experiments	Investigation	YES
4232858	24460655	D Cappellini	2	served as investigators on this trial, enrolling patients|contributed to data interpretation, reviewed and provided their comments on this manuscript|served as study steering committee members overseeing the conduct of the trial, from study design to analysis plan and data interpretation	contributed to data interpretation, reviewed and provided their comments on this manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4232858	24460655	D Cappellini	2	served as investigators on this trial, enrolling patients|contributed to data interpretation, reviewed and provided their comments on this manuscript|served as study steering committee members overseeing the conduct of the trial, from study design to analysis plan and data interpretation	served as study steering committee members overseeing the conduct of the trial, from study design to analysis plan and data interpretation	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology|Supervision	YES
4232858	24460655	D Habr	2	assisted in developing the trial protocol	assisted in developing the trial protocol	Conceived and designed the experiments	Methodology	YES
4232858	24460655	Z Zhu	2	served as the trial statistician	served as the trial statistician	Analyzed the data	Formal analysis	YES
4619880	26539522	Gerald Fogarty	2	are responsible for the initiation and coordination of the entire study	are responsible for the initiation and coordination of the entire study	-	Project administration	YES
4619880	26539522	Gina Hesselberg	2	are responsible for the initiation and coordination of the entire study	are responsible for the initiation and coordination of the entire study	-	Project administration	YES
5321639	28229435	All authors	2	reviewed the manuscript|read and approved the final manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5321639	28229435	All authors	2	reviewed the manuscript|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5321639	28229435	DT	2	conceived and designed the research	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5321639	28229435	HXC	2	designed peptides and performed the in vitro pharmacodynamics	designed peptides and performed the in vitro pharmacodynamics	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5321639	28229435	JHW	2	conceived and designed the research|wrote the manuscript	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5321639	28229435	JHW	2	conceived and designed the research|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5321639	28229435	RYM	2	conceived and designed the research|wrote the manuscript	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5321639	28229435	RYM	2	conceived and designed the research|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5321639	28229435	XJF	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4415813	25927358	JM	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415813	25927358	KJW	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415813	25927358	KM	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415813	25927358	MP	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5760538	29354138	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5760538	29354138	DL	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5760538	29354138	NT-Z	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4551353	26101372	AJF	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4551353	26101372	CPT	2	contributed reagents and experimental data	contributed reagents and experimental data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4551353	26101372	DEC	2	directed the experiments described in figs 5 7 supplementary figs s2 s3 s4 s5a s6 s7|wrote the manuscript	directed the experiments described in figs 5 7 supplementary figs s2 s3 s4 s5a s6 s7	-	Supervision	YES
4551353	26101372	DEC	2	directed the experiments described in figs 5 7 supplementary figs s2 s3 s4 s5a s6 s7|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4551353	26101372	GJT	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4551353	26101372	PJL	2	provided the e2 rnai library and protocol	provided the e2 rnai library and protocol	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Methodology|Resources	YES
4551353	26101372	TS	2	contributed reagents and experimental data	contributed reagents and experimental data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4551353	26101372	WIS	2	directed the experiments described in figs 5 7 supplementary figs s2 s3 s4 s5a s6 s7|wrote the manuscript	directed the experiments described in figs 5 7 supplementary figs s2 s3 s4 s5a s6 s7	-	Supervision	YES
4551353	26101372	WIS	2	directed the experiments described in figs 5 7 supplementary figs s2 s3 s4 s5a s6 s7|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5678779	29115918	All authors	2	read, edited and approved the final manuscript	read, edited and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5678779	29115918	RH	2	author participated sufficiently in the work to take public responsibility for appropriate portions of the content	author participated sufficiently in the work to take public responsibility for appropriate portions of the content	-	-	NO
5678779	29115918	TMD	2	author participated sufficiently in the work to take public responsibility for appropriate portions of the content	author participated sufficiently in the work to take public responsibility for appropriate portions of the content	-	-	NO
1934933	17684560	AD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1934933	17684560	AD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1934933	17684560	AD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1934933	17684560	AD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1934933	17684560	AH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1934933	17684560	AH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1934933	17684560	AH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1934933	17684560	AH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1934933	17684560	YP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1934933	17684560	YP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1934933	17684560	YP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1934933	17684560	YP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1934933	17684560	YP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415814	25928898	AA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415814	25928898	AA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415814	25928898	AA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415814	25928898	AA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415814	25928898	AA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415814	25928898	CM	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415814	25928898	FB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415814	25928898	FB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415814	25928898	FB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415814	25928898	FB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415814	25928898	FB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415814	25928898	GD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415814	25928898	GD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415814	25928898	GD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415814	25928898	GD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415814	25928898	GD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415814	25928898	SM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415814	25928898	TVF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415814	25928898	TVF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415814	25928898	TVF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415814	25928898	TVF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415814	25928898	TVF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5034497	27688737	AH	2	carried out experiments	carried out experiments	Performed the experiments	Investigation	YES
5034497	27688737	AI	2	supervised research work and drafted the manuscript	supervised research work and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Original Draft	YES
5034497	27688737	AK	2	supervised research work and drafted the manuscript	supervised research work and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Original Draft	YES
5034497	27688737	BM	2	supervised research work and drafted the manuscript	supervised research work and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Original Draft	YES
5034497	27688737	BR	2	carried out experiments	carried out experiments	Performed the experiments	Investigation	YES
5034497	27688737	HA	2	carried out experiments	carried out experiments	Performed the experiments	Investigation	YES
5034497	27688737	JS	2	carried out experiments	carried out experiments	Performed the experiments	Investigation	YES
5034497	27688737	NJ	2	wrote the manuscript|carried out experiments	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5034497	27688737	NJ	2	wrote the manuscript|carried out experiments	carried out experiments	Performed the experiments	Investigation	YES
5321645	28229436	All	2	datasets on which the conclusions of the manuscript rely are presented in the main paper	datasets on which the conclusions of the manuscript rely are presented in the main paper	-	-	NO
5321645	28229436	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5321645	28229436	FL	2	conceived and coordinated the study, and helped in the drafting of the manuscript	conceived and coordinated the study, and helped in the drafting of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Project administration|Writing - Original Draft	YES
5321645	28229436	KRZ	2	participated in some of the experiments	participated in some of the experiments	Performed the experiments	Investigation	YES
5321645	28229436	MHZ	2	participated in some of the experiments	participated in some of the experiments	Performed the experiments	Investigation	YES
5321645	28229436	RZ	2	designed and conducted the bulk of the experiments, performed analysis and interpretation of data, and drafted the manuscript	designed and conducted the bulk of the experiments, performed analysis and interpretation of data, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5321645	28229436	TBN	2	gave advice in the study and edited the manuscript	gave advice in the study and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5321645	28229436	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5321645	28229436	YJH	2	participated in some of the experiments	participated in some of the experiments	Performed the experiments	Investigation	YES
1934934	17684550	GS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1934934	17684550	GS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1934934	17684550	GS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1934934	17684550	HN	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1934934	17684550	HN	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4570519	26240067	ADC	2	to acquisition of data	to acquisition of data	Performed the experiments	Investigation	YES
4570519	26240067	AH	2	to analysis and interpretation of the data|to statistical analysis	to analysis and interpretation of the data	Analyzed the data	Formal analysis	YES
4570519	26240067	AH	2	to analysis and interpretation of the data|to statistical analysis	to statistical analysis	Analyzed the data	Formal analysis	YES
4570519	26240067	AM	2	to provision of reagents	to provision of reagents	-	-	NO
4570519	26240067	ARC	2	contributed to study concept and design	contributed to study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4570519	26240067	AW	2	to analysis and interpretation of the data	to analysis and interpretation of the data	Analyzed the data	Formal analysis	YES
4570519	26240067	BD	2	to acquisition of data|to analysis and interpretation of the data	to acquisition of data	Performed the experiments	Investigation	YES
4570519	26240067	BD	2	to acquisition of data|to analysis and interpretation of the data	to analysis and interpretation of the data	Analyzed the data	Formal analysis	YES
4570519	26240067	DJH	2	contributed to study concept and design|to acquisition of data|to analysis and interpretation of the data|to drafting of the manuscript	contributed to study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4570519	26240067	DJH	2	contributed to study concept and design|to acquisition of data|to analysis and interpretation of the data|to drafting of the manuscript	to acquisition of data	Performed the experiments	Investigation	YES
4570519	26240067	DJH	2	contributed to study concept and design|to acquisition of data|to analysis and interpretation of the data|to drafting of the manuscript	to analysis and interpretation of the data	Analyzed the data	Formal analysis	YES
4570519	26240067	DJH	2	contributed to study concept and design|to acquisition of data|to analysis and interpretation of the data|to drafting of the manuscript	to drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
4570519	26240067	FC	2	to acquisition of data|to analysis and interpretation of the data	to acquisition of data	Performed the experiments	Investigation	YES
4570519	26240067	FC	2	to acquisition of data|to analysis and interpretation of the data	to analysis and interpretation of the data	Analyzed the data	Formal analysis	YES
4570519	26240067	FS	2	to acquisition of data	to acquisition of data	Performed the experiments	Investigation	YES
4570519	26240067	GK	2	to statistical analysis	to statistical analysis	Analyzed the data	Formal analysis	YES
4570519	26240067	GM	2	to acquisition of data	to acquisition of data	Performed the experiments	Investigation	YES
4570519	26240067	JM	2	to acquisition of data	to acquisition of data	Performed the experiments	Investigation	YES
4570519	26240067	KRR	2	to acquisition of data	to acquisition of data	Performed the experiments	Investigation	YES
4570519	26240067	LL	2	to analysis and interpretation of the data	to analysis and interpretation of the data	Analyzed the data	Formal analysis	YES
4570519	26240067	LP	2	to acquisition of data	to acquisition of data	Performed the experiments	Investigation	YES
4570519	26240067	ML	2	to acquisition of data	to acquisition of data	Performed the experiments	Investigation	YES
4570519	26240067	NB	2	to acquisition of data	to acquisition of data	Performed the experiments	Investigation	YES
4570519	26240067	OJS	2	contributed to study concept and design|to drafting of the manuscript	contributed to study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4570519	26240067	OJS	2	contributed to study concept and design|to drafting of the manuscript	to drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
4570519	26240067	OS	2	to analysis and interpretation of the data	to analysis and interpretation of the data	Analyzed the data	Formal analysis	YES
4570519	26240067	RAR	2	contributed to study concept and design|to acquisition of data|to analysis and interpretation of the data|to drafting of the manuscript	contributed to study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4570519	26240067	RAR	2	contributed to study concept and design|to acquisition of data|to analysis and interpretation of the data|to drafting of the manuscript	to acquisition of data	Performed the experiments	Investigation	YES
4570519	26240067	RAR	2	contributed to study concept and design|to acquisition of data|to analysis and interpretation of the data|to drafting of the manuscript	to analysis and interpretation of the data	Analyzed the data	Formal analysis	YES
4570519	26240067	RAR	2	contributed to study concept and design|to acquisition of data|to analysis and interpretation of the data|to drafting of the manuscript	to drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
4570519	26240067	RC	2	to provision of reagents	to provision of reagents	-	-	NO
4570519	26240067	SB	2	to acquisition of data	to acquisition of data	Performed the experiments	Investigation	YES
4570519	26240067	SL	2	to acquisition of data	to acquisition of data	Performed the experiments	Investigation	YES
4570519	26240067	SR	2	to acquisition of data|to analysis and interpretation of the data	to acquisition of data	Performed the experiments	Investigation	YES
4570519	26240067	SR	2	to acquisition of data|to analysis and interpretation of the data	to analysis and interpretation of the data	Analyzed the data	Formal analysis	YES
4570519	26240067	SS	2	to provision of reagents	to provision of reagents	-	-	NO
4570519	26240067	VSM	2	to acquisition of data	to acquisition of data	Performed the experiments	Investigation	YES
5680602	29121856	CX	2	participated in the data analysis	participated in the data analysis	Analyzed the data	Formal analysis	YES
5680602	29121856	HF	2	participated in the data analysis	participated in the data analysis	Analyzed the data	Formal analysis	YES
5680602	29121856	JZ	2	designed the research and wrote the paper	designed the research and wrote the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5680602	29121856	LZ	2	performed the experiments, analyzed the data and wrote the paper	performed the experiments, analyzed the data and wrote the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5680602	29121856	ML	2	designed the research and wrote the paper	designed the research and wrote the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5680602	29121856	ZL	2	performed the experiments, analyzed the data and wrote the paper	performed the experiments, analyzed the data and wrote the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
1934935	17684562	DR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1934935	17684562	DR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1934935	17684562	DR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1934935	17684562	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1934935	17684562	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1934935	17684562	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1934935	17684562	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1934935	17684562	KC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1934935	17684562	KC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1934935	17684562	KC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1934935	17684562	MS	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1934935	17684562	MS	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1934935	17684562	NA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1934935	17684562	NA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1934935	17684562	NA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1934935	17684562	NA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1934935	17684562	TC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1934935	17684562	TC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1934935	17684562	TC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1934935	17684562	TC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1934935	17684562	WS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1934935	17684562	WS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1934935	17684562	WS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5057468	27777541	David J. Beale	2	was responsible for the sole content of this article	was responsible for the sole content of this article	-	-	NO
5760540	29354152	AZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5760540	29354152	CL	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
5760540	29354152	CL	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5760540	29354152	DR	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5760540	29354152	GC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote and revised the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5760540	29354152	GC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote and revised the paper	Performed the experiments	Performed the experiments	Investigation	YES
5760540	29354152	GC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote and revised the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5760540	29354152	GC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote and revised the paper	Wrote and revised the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5760540	29354152	GX	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote and revised the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5760540	29354152	GX	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote and revised the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5760540	29354152	GX	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote and revised the paper	Wrote and revised the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5760540	29354152	JH	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5760540	29354152	LY	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5760540	29354152	LZ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5760540	29354152	QQ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote and revised the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5760540	29354152	QQ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote and revised the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5760540	29354152	QQ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote and revised the paper	Wrote and revised the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5760540	29354152	YZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5760540	29354152	ZG	PLoS5	Analyzed the data|Wrote and revised the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5760540	29354152	ZG	PLoS5	Analyzed the data|Wrote and revised the paper	Wrote and revised the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4415815	25928633	AB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4415815	25928633	AS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4415815	25928633	CCV	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415815	25928633	DSM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4415815	25928633	FM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415815	25928633	FM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415815	25928633	FM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415815	25928633	FM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415815	25928633	FM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415815	25928633	MFD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415815	25928633	MFD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415815	25928633	MFD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415815	25928633	MFD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415815	25928633	MFD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415815	25928633	MHP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415815	25928633	MHP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415815	25928633	MHP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415815	25928633	MHP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415815	25928633	MHP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415815	25928633	MR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415815	25928633	MR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415815	25928633	MR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415815	25928633	MR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415815	25928633	SR	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415815	25928633	SR	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415815	25928633	SR	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5680758	29121875	CC	2	performed bioinformatic, pathway and statistical analyses	performed bioinformatic, pathway and statistical analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5680758	29121875	DK	2	conceived the study and participated in its design and coordination and helped to draft the manuscript|performed the animal study	conceived the study and participated in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
5680758	29121875	DK	2	conceived the study and participated in its design and coordination and helped to draft the manuscript|performed the animal study	performed the animal study	Performed the experiments	Investigation	YES
5680758	29121875	DM	2	performed the animal study|performed the molecular analyses|performed bioinformatic, pathway and statistical analyses|drafted the manuscript	performed the animal study	Performed the experiments	Investigation	YES
5680758	29121875	DM	2	performed the animal study|performed the molecular analyses|performed bioinformatic, pathway and statistical analyses|drafted the manuscript	performed the molecular analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5680758	29121875	DM	2	performed the animal study|performed the molecular analyses|performed bioinformatic, pathway and statistical analyses|drafted the manuscript	performed bioinformatic, pathway and statistical analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5680758	29121875	DM	2	performed the animal study|performed the molecular analyses|performed bioinformatic, pathway and statistical analyses|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5680758	29121875	KK	2	performed bioinformatic, pathway and statistical analyses	performed bioinformatic, pathway and statistical analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5680758	29121875	MD	2	conceived the study and participated in its design and coordination and helped to draft the manuscript|performed the animal study	conceived the study and participated in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
5680758	29121875	MD	2	conceived the study and participated in its design and coordination and helped to draft the manuscript|performed the animal study	performed the animal study	Performed the experiments	Investigation	YES
5680758	29121875	SW	2	conceived the study and participated in its design and coordination and helped to draft the manuscript|performed the molecular analyses|drafted the manuscript	conceived the study and participated in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
5680758	29121875	SW	2	conceived the study and participated in its design and coordination and helped to draft the manuscript|performed the molecular analyses|drafted the manuscript	performed the molecular analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5680758	29121875	SW	2	conceived the study and participated in its design and coordination and helped to draft the manuscript|performed the molecular analyses|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5323333	28233286	AAAK	2	arranged funding and helped in preparing the manuscript	arranged funding and helped in preparing the manuscript	Wrote the paper	Funding acquisition|Writing - Original Draft	YES
5323333	28233286	All	2	the data are provided as an excel sheet except for the data on purification and characterization of carvacrol and thymol that will be published elsewhere	the data are provided as an excel sheet except for the data on purification and characterization of carvacrol and thymol that will be published elsewhere	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5323333	28233286	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5323333	28233286	HZA	2	arranged funding and helped in preparing the manuscript	arranged funding and helped in preparing the manuscript	Wrote the paper	Funding acquisition|Writing - Original Draft	YES
5323333	28233286	JA	2	he did rna isolation and rt pcr studies	he did rna isolation and rt pcr studies	Performed the experiments	Investigation	YES
5323333	28233286	JM	2	arranged funding and helped in preparing the manuscript	arranged funding and helped in preparing the manuscript	Wrote the paper	Funding acquisition|Writing - Original Draft	YES
5323333	28233286	MK	2	he collected the plant sample and isolated and identified thymol and carvacrol therefrom	he collected the plant sample and isolated and identified thymol and carvacrol therefrom	Performed the experiments	Investigation	YES
5323333	28233286	OHAE	2	carried out the sem studies	carried out the sem studies	Performed the experiments	Investigation	YES
5323333	28233286	RW	2	he helped in microbiological studies	he helped in microbiological studies	-	-	NO
5323333	28233286	STK	2	main author designed and executed the study	main author designed and executed the study	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5323333	28233286	Saud Arabia	2	for support	for support	-	-	NO
5323333	28233286	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
4415816	25928067	DJ	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4415816	25928067	JF	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415816	25928067	JF	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415816	25928067	JW	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4415816	25928067	KW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415816	25928067	KW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415816	25928067	LY	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415816	25928067	TY	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4415816	25928067	TY	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415816	25928067	WL	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4415816	25928067	YL	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415816	25928067	YL	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415816	25928067	YS	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415816	25928067	YS	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415816	25928067	YS	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415816	25928067	YS	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1934936	17684564	BV	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1934936	17684564	BV	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1934936	17684564	BV	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1934936	17684564	BV	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1934936	17684564	DW	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1934936	17684564	DW	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1934936	17684564	DW	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1934936	17684564	DW	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1934936	17684564	GW	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1934936	17684564	HN	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1934936	17684564	HN	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1934936	17684564	NP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1934936	17684564	NP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1934936	17684564	NP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1934936	17684564	NP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1934936	17684564	NP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1934936	17684564	RA	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1934936	17684564	RA	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
3863453	24379736	Peng Zhiyou	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
3863453	24379736	Yang Meijuan	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
5760546	29354145	All authors	2	discussed the results, commented on the manuscript and approved the final manuscript	discussed the results, commented on the manuscript and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5760546	29354145	H-PP	2	developed alternative methods generating the two-phase experimental designs|revised the manuscript	developed alternative methods generating the two-phase experimental designs	Conceived and designed the experiments|Performed the experiments	Methodology	YES
5760546	29354145	H-PP	2	developed alternative methods generating the two-phase experimental designs|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5760546	29354145	HM	2	developed alternative methods generating the two-phase experimental designs|conducted post hoc analysis of the experiment 2013/14, the dummy analyses and prepared the manuscript	developed alternative methods generating the two-phase experimental designs	Conceived and designed the experiments|Performed the experiments	Methodology	YES
5760546	29354145	HM	2	developed alternative methods generating the two-phase experimental designs|conducted post hoc analysis of the experiment 2013/14, the dummy analyses and prepared the manuscript	conducted post hoc analysis of the experiment 2013/14, the dummy analyses and prepared the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5760546	29354145	RB	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5070225	27777542	ARJ	2	assisted with data analysis and manuscript preparation	assisted with data analysis and manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5070225	27777542	DRB	2	assisted with manuscript preparation	assisted with manuscript preparation	Wrote the paper	Writing - Original Draft	YES
5070225	27777542	JMO	2	assisted with data analysis and manuscript preparation	assisted with data analysis and manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5070225	27777542	MG	2	assisted with study design and manuscript preparation	assisted with study design and manuscript preparation	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5070225	27777542	MTJ	2	designed the study, oversaw data collection, data analysis and manuscript preparation	designed the study, oversaw data collection, data analysis and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Supervision|Writing - Original Draft	YES
5070225	27777542	MVH	2	assisted with manuscript preparation	assisted with manuscript preparation	Wrote the paper	Writing - Original Draft	YES
4585460	26136213	HS	PLoS52	conceived and designed the human patient experiments|wrote the paper	conceived and designed the human patient experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4585460	26136213	HS	PLoS52	conceived and designed the human patient experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4585460	26136213	IJC	PLoS52	performed the statistical analysis in figs 5 6	performed the statistical analysis in figs 5 6	Analyzed the data	Formal analysis	YES
4585460	26136213	JC	PLoS52	performed the zebrafish experiments|wrote the paper	performed the zebrafish experiments	Performed the experiments	Investigation	YES
4585460	26136213	JC	PLoS52	performed the zebrafish experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4585460	26136213	LCW	PLoS52	performed the zebrafish experiments|wrote the paper	performed the zebrafish experiments	Performed the experiments	Investigation	YES
4585460	26136213	LCW	PLoS52	performed the zebrafish experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4585460	26136213	MLB-B	PLoS52	conceived and designed the human patient experiments|performed the experiments in figs 5 and 6|wrote the paper	conceived and designed the human patient experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4585460	26136213	MLB-B	PLoS52	conceived and designed the human patient experiments|performed the experiments in figs 5 and 6|wrote the paper	performed the experiments in figs 5 and 6	Performed the experiments	Investigation	YES
4585460	26136213	MLB-B	PLoS52	conceived and designed the human patient experiments|performed the experiments in figs 5 and 6|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4585460	26136213	NA	PLoS52	conceived and designed the zebrafish experiments|performed the zebrafish experiments|wrote the paper	conceived and designed the zebrafish experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4585460	26136213	NA	PLoS52	conceived and designed the zebrafish experiments|performed the zebrafish experiments|wrote the paper	performed the zebrafish experiments	Performed the experiments	Investigation	YES
4585460	26136213	NA	PLoS52	conceived and designed the zebrafish experiments|performed the zebrafish experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4585460	26136213	PM	PLoS52	conceived and designed the zebrafish experiments|wrote the paper	conceived and designed the zebrafish experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4585460	26136213	PM	PLoS52	conceived and designed the zebrafish experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4585460	26136213	TS	PLoS52	conceived and designed the human patient experiments	conceived and designed the human patient experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4585460	26136213	YF	PLoS52	conceived and designed the zebrafish experiments|wrote the paper	conceived and designed the zebrafish experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4585460	26136213	YF	PLoS52	conceived and designed the zebrafish experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4619898	26539538	All authors	2	read and approved the final paper	read and approved the final paper	-	-	NO
4619898	26539538	Chao-Yuan Huang	2	performed the operations and further paper editing	performed the operations and further paper editing	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4619898	26539538	Che-Yuan Hu	2	designed this study and collected clinical data|drafted this paper|contributed equally to this paper	designed this study and collected clinical data	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4619898	26539538	Che-Yuan Hu	2	designed this study and collected clinical data|drafted this paper|contributed equally to this paper	drafted this paper	Wrote the paper	Writing - Original Draft	YES
4619898	26539538	Che-Yuan Hu	2	designed this study and collected clinical data|drafted this paper|contributed equally to this paper	contributed equally to this paper	-	-	NO
4619898	26539538	Cheng-Kuang Yang	2	designed this study and collected clinical data|contributed equally to this paper	designed this study and collected clinical data	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4619898	26539538	Cheng-Kuang Yang	2	designed this study and collected clinical data|contributed equally to this paper	contributed equally to this paper	-	-	NO
4619898	26539538	Shiu-Dong Chung	2	collected clinical data	collected clinical data	Performed the experiments	Investigation	YES
4619898	26539538	Shun-Fa Hung	2	collected clinical data	collected clinical data	Performed the experiments	Investigation	YES
4619898	26539538	Yen-Chuan Ou	2	performed the operations and further paper editing	performed the operations and further paper editing	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4619898	26539538	Yeong-Shiau Pu	2	performed the operations and further paper editing	performed the operations and further paper editing	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4415817	25927603	AEO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415817	25927603	AEO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415817	25927603	AEO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415817	25927603	AEO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415817	25927603	AMB	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415817	25927603	CS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415817	25927603	CS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415817	25927603	CS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415817	25927603	HP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415817	25927603	HP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415817	25927603	HP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415817	25927603	HP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415817	25927603	HP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415817	25927603	JS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415817	25927603	JS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415817	25927603	JS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415817	25927603	JS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415817	25927603	MM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415817	25927603	MM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415817	25927603	SS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1936222	17684545	AH	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1936222	17684545	AZ	PLoS5	Analyzed the data|Wrote the paper|Developed the theory	Analyzed the data	Analyzed the data	Formal analysis	YES
1936222	17684545	AZ	PLoS5	Analyzed the data|Wrote the paper|Developed the theory	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1936222	17684545	AZ	PLoS5	Analyzed the data|Wrote the paper|Developed the theory	Developed the theory	-	-	NO
1936222	17684545	FJ	PLoS5	Wrote the paper|Developed the theory	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1936222	17684545	FJ	PLoS5	Wrote the paper|Developed the theory	Developed the theory	-	-	NO
1936222	17684545	HB	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1936222	17684545	HB	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1936222	17684545	KK	PLoS5	Wrote the paper|Developed the theory	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1936222	17684545	KK	PLoS5	Wrote the paper|Developed the theory	Developed the theory	-	-	NO
5323338	28233287	All	2	patients provided written consent prior to sample collection	patients provided written consent prior to sample collection	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Resources|Writing - Original Draft	YES
5323338	28233287	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5323338	28233287	JQH	2	carried out the molecular genetic studies	carried out the molecular genetic studies	Performed the experiments	Investigation	YES
5323338	28233287	ML	2	carried out the molecular genetic studies|participated in the sequence alignment and drafted the manuscript|collected clinical samples	carried out the molecular genetic studies	Performed the experiments	Investigation	YES
5323338	28233287	ML	2	carried out the molecular genetic studies|participated in the sequence alignment and drafted the manuscript|collected clinical samples	participated in the sequence alignment and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5323338	28233287	ML	2	carried out the molecular genetic studies|participated in the sequence alignment and drafted the manuscript|collected clinical samples	collected clinical samples	Performed the experiments	Investigation	YES
5323338	28233287	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5323338	28233287	XGG	2	carried out the molecular genetic studies|participated in the sequence alignment and drafted the manuscript|conceived of the study, and participated in its design and coordination and helped to draft the manuscript	carried out the molecular genetic studies	Performed the experiments	Investigation	YES
5323338	28233287	XGG	2	carried out the molecular genetic studies|participated in the sequence alignment and drafted the manuscript|conceived of the study, and participated in its design and coordination and helped to draft the manuscript	participated in the sequence alignment and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5323338	28233287	XGG	2	carried out the molecular genetic studies|participated in the sequence alignment and drafted the manuscript|conceived of the study, and participated in its design and coordination and helped to draft the manuscript	conceived of the study, and participated in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
5323338	28233287	XZW	2	collected clinical samples	collected clinical samples	Performed the experiments	Investigation	YES
5323338	28233287	YX	2	participated in the design of the study and performed the analysis	participated in the design of the study and performed the analysis	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5760558	29354150	CW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5760558	29354150	HY	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5760558	29354150	MZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5760558	29354150	QL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5760558	29354150	QL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
5760558	29354150	QL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5760558	29354150	QL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5760558	29354150	QX	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5760558	29354150	SW	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5760558	29354150	XC	PLoS5	Revised the manuscript	Revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5760558	29354150	XL	PLoS5	Revised the manuscript	Revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5760558	29354150	XN	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5760558	29354150	XN	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5760558	29354150	XW	PLoS5	Conceived and designed the experiments|Revised the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5760558	29354150	XW	PLoS5	Conceived and designed the experiments|Revised the manuscript	Revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5760558	29354150	XY	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5760558	29354150	YF	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5760558	29354150	YW	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5760558	29354150	YY	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4585463	26139536	DGC	2	interpreted mass spectrometry data	interpreted mass spectrometry data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5093951	27822169	All other authors	2	read and reviewed the final manuscript	read and reviewed the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5093951	27822169	DAB	2	performed data analysis and statistics and contributed to drafting the manuscript	performed data analysis and statistics and contributed to drafting the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5093951	27822169	MDV	2	assisted with study design and statistical analysis	assisted with study design and statistical analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5093951	27822169	MJO	2	conceived of the study, carried out data collection and developed the draft of manuscript	conceived of the study, carried out data collection and developed the draft of manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
5093951	27822169	MTS	2	assisted with study design and statistical analysis	assisted with study design and statistical analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5093951	27822169	SJK	2	conceived of the study, carried out data collection and developed the draft of manuscript	conceived of the study, carried out data collection and developed the draft of manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
5680769	29121861	HL	PLoS52	conducted the research|analyzed the data	conducted the research	Performed the experiments	Investigation	YES
5680769	29121861	HL	PLoS52	conducted the research|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5680769	29121861	IJ	PLoS52	interpreted the data|wrote the manuscript|revised the manuscript critically for important intellectual content	interpreted the data	Analyzed the data	Formal analysis	YES
5680769	29121861	IJ	PLoS52	interpreted the data|wrote the manuscript|revised the manuscript critically for important intellectual content	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5680769	29121861	IJ	PLoS52	interpreted the data|wrote the manuscript|revised the manuscript critically for important intellectual content	revised the manuscript critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5680769	29121861	PP	PLoS52	provided the materials|collected the data|analyzed the data	provided the materials	Contributed reagents/materials/analysis tools	Resources	YES
5680769	29121861	PP	PLoS52	provided the materials|collected the data|analyzed the data	collected the data	Performed the experiments	Investigation	YES
5680769	29121861	PP	PLoS52	provided the materials|collected the data|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5680769	29121861	WP	PLoS52	designed the study|conducted the research|provided the materials|collected the data|analyzed the data|interpreted the data|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5680769	29121861	WP	PLoS52	designed the study|conducted the research|provided the materials|collected the data|analyzed the data|interpreted the data|wrote the manuscript	conducted the research	Performed the experiments	Investigation	YES
5680769	29121861	WP	PLoS52	designed the study|conducted the research|provided the materials|collected the data|analyzed the data|interpreted the data|wrote the manuscript	provided the materials	Contributed reagents/materials/analysis tools	Resources	YES
5680769	29121861	WP	PLoS52	designed the study|conducted the research|provided the materials|collected the data|analyzed the data|interpreted the data|wrote the manuscript	collected the data	Performed the experiments	Investigation	YES
5680769	29121861	WP	PLoS52	designed the study|conducted the research|provided the materials|collected the data|analyzed the data|interpreted the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5680769	29121861	WP	PLoS52	designed the study|conducted the research|provided the materials|collected the data|analyzed the data|interpreted the data|wrote the manuscript	interpreted the data	Analyzed the data	Formal analysis	YES
5680769	29121861	WP	PLoS52	designed the study|conducted the research|provided the materials|collected the data|analyzed the data|interpreted the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5680769	29121861	WW	PLoS52	conceptualized the study|designed the study|revised the manuscript critically for important intellectual content	conceptualized the study	Conceived and designed the experiments	Conceptualization	YES
5680769	29121861	WW	PLoS52	conceptualized the study|designed the study|revised the manuscript critically for important intellectual content	designed the study	Conceived and designed the experiments	Methodology	YES
5680769	29121861	WW	PLoS52	conceptualized the study|designed the study|revised the manuscript critically for important intellectual content	revised the manuscript critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5680769	29121861	YZ	PLoS52	conceptualized the study|designed the study|conducted the research|provided the materials|collected the data|interpreted the data|revised the manuscript critically for important intellectual content	conceptualized the study	Conceived and designed the experiments	Conceptualization	YES
5680769	29121861	YZ	PLoS52	conceptualized the study|designed the study|conducted the research|provided the materials|collected the data|interpreted the data|revised the manuscript critically for important intellectual content	designed the study	Conceived and designed the experiments	Methodology	YES
5680769	29121861	YZ	PLoS52	conceptualized the study|designed the study|conducted the research|provided the materials|collected the data|interpreted the data|revised the manuscript critically for important intellectual content	conducted the research	Performed the experiments	Investigation	YES
5680769	29121861	YZ	PLoS52	conceptualized the study|designed the study|conducted the research|provided the materials|collected the data|interpreted the data|revised the manuscript critically for important intellectual content	provided the materials	Contributed reagents/materials/analysis tools	Resources	YES
5680769	29121861	YZ	PLoS52	conceptualized the study|designed the study|conducted the research|provided the materials|collected the data|interpreted the data|revised the manuscript critically for important intellectual content	collected the data	Performed the experiments	Investigation	YES
5680769	29121861	YZ	PLoS52	conceptualized the study|designed the study|conducted the research|provided the materials|collected the data|interpreted the data|revised the manuscript critically for important intellectual content	interpreted the data	Analyzed the data	Formal analysis	YES
5680769	29121861	YZ	PLoS52	conceptualized the study|designed the study|conducted the research|provided the materials|collected the data|interpreted the data|revised the manuscript critically for important intellectual content	revised the manuscript critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4415818	25927364	BAT	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415818	25927364	BAT	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415818	25927364	DDF	PLoS5	Contributed reagents/materials/analysis tools|Read and contributed to finalization of the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415818	25927364	DDF	PLoS5	Contributed reagents/materials/analysis tools|Read and contributed to finalization of the manuscript	Read and contributed to finalization of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4415818	25927364	DJH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Read and contributed to finalization of the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415818	25927364	DJH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Read and contributed to finalization of the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4415818	25927364	DJH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Read and contributed to finalization of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4415818	25927364	DJH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Read and contributed to finalization of the manuscript	Read and contributed to finalization of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4415818	25927364	DMS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Read and contributed to finalization of the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415818	25927364	DMS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Read and contributed to finalization of the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415818	25927364	DMS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Read and contributed to finalization of the manuscript	Read and contributed to finalization of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4415818	25927364	GNT	PLoS5	Analyzed the data|Read and contributed to finalization of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4415818	25927364	GNT	PLoS5	Analyzed the data|Read and contributed to finalization of the manuscript	Read and contributed to finalization of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4415818	25927364	HJK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415818	25927364	HJK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415818	25927364	HJK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415818	25927364	HJK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415818	25927364	HSM	PLoS5	Performed the experiments|Read and contributed to finalization of the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4415818	25927364	HSM	PLoS5	Performed the experiments|Read and contributed to finalization of the manuscript	Read and contributed to finalization of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4415818	25927364	KMY	PLoS5	Conceived and designed the experiments|Analyzed the data|Read and contributed to finalization of the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415818	25927364	KMY	PLoS5	Conceived and designed the experiments|Analyzed the data|Read and contributed to finalization of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4415818	25927364	KMY	PLoS5	Conceived and designed the experiments|Analyzed the data|Read and contributed to finalization of the manuscript	Read and contributed to finalization of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4415818	25927364	MKG	PLoS5	Performed the experiments|Read and contributed to finalization of the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4415818	25927364	MKG	PLoS5	Performed the experiments|Read and contributed to finalization of the manuscript	Read and contributed to finalization of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4415818	25927364	RBT	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Read and contributed to finalization of the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4415818	25927364	RBT	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Read and contributed to finalization of the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415818	25927364	RBT	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Read and contributed to finalization of the manuscript	Read and contributed to finalization of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4415818	25927364	ZJC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Read and contributed to finalization of the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415818	25927364	ZJC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Read and contributed to finalization of the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415818	25927364	ZJC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Read and contributed to finalization of the manuscript	Read and contributed to finalization of the manuscript	Wrote the paper	Writing - Review & Editing	YES
1936433	17710135	AQ	PLoS5	Contributed reagents/materials/analysis tools|Patient recruitment, clinical assessment, grouping of patients	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1936433	17710135	AQ	PLoS5	Contributed reagents/materials/analysis tools|Patient recruitment, clinical assessment, grouping of patients	Patient recruitment, clinical assessment, grouping of patients	Performed the experiments	Investigation	YES
1936433	17710135	AY	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1936433	17710135	FK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the study|Wrote the first draft of the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1936433	17710135	FK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the study|Wrote the first draft of the paper	Performed the experiments	Performed the experiments	Investigation	YES
1936433	17710135	FK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the study|Wrote the first draft of the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1936433	17710135	FK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the study|Wrote the first draft of the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1936433	17710135	FK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the study|Wrote the first draft of the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1936433	17710135	FK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the study|Wrote the first draft of the paper	Designed the study	Conceived and designed the experiments	Methodology	YES
1936433	17710135	FK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the study|Wrote the first draft of the paper	Wrote the first draft of the paper	Wrote the paper	Writing - Original Draft	YES
1936433	17710135	GL	PLoS5	Contributed reagents/materials/analysis tools|Patient recruitment, clinical assessment, grouping of patients	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1936433	17710135	GL	PLoS5	Contributed reagents/materials/analysis tools|Patient recruitment, clinical assessment, grouping of patients	Patient recruitment, clinical assessment, grouping of patients	Performed the experiments	Investigation	YES
1936433	17710135	HM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1936433	17710135	HM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1936433	17710135	HV	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1936433	17710135	HV	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1936433	17710135	LN	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1936433	17710135	LN	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1936433	17710135	LT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1936433	17710135	LT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1936433	17710135	LT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1936433	17710135	LT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1936433	17710135	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1936433	17710135	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1936433	17710135	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1936433	17710135	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1936433	17710135	RL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1936433	17710135	RL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1936433	17710135	TU	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1936433	17710135	TU	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1936433	17710135	VY	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1936433	17710135	VY	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5328894	28244030	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5328894	28244030	FO	2	conceived of the study, participated in its design and coordination, interpreted the data and helped to draft the manuscript	conceived of the study, participated in its design and coordination, interpreted the data and helped to draft the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Project administration|Writing - Original Draft	YES
5328894	28244030	KN	2	performed the experiments and the data analysis	performed the experiments and the data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5328894	28244030	Kazuaki Okawa	2	for their valuable suggestions and the technical assistance	for their valuable suggestions and the technical assistance	Performed the experiments	Investigation	YES
5328894	28244030	MK	2	conceived of the study, participated in its design and coordination, interpreted the data, and drafted the manuscript	conceived of the study, participated in its design and coordination, interpreted the data, and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Project administration|Writing - Original Draft	YES
5328894	28244030	MS	2	conceived of the study, participated in its design and coordination, interpreted the data, and drafted the manuscript	conceived of the study, participated in its design and coordination, interpreted the data, and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Project administration|Writing - Original Draft	YES
5328894	28244030	Masahiro Kimura	2	for their valuable suggestions and the technical assistance	for their valuable suggestions and the technical assistance	Performed the experiments	Investigation	YES
5328894	28244030	Misa Ohno	2	for their valuable suggestions and the technical assistance	for their valuable suggestions and the technical assistance	Performed the experiments	Investigation	YES
5328894	28244030	SH	2	conceived of the study, participated in its design and coordination, performed the experiments, interpreted the data, and drafted the manuscript	conceived of the study, participated in its design and coordination, performed the experiments, interpreted the data, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Project administration|Writing - Original Draft	YES
5328894	28244030	SW	2	participated in its design and coordination, performed the experiments, interpreted the data, and helped to draft the manuscript	participated in its design and coordination, performed the experiments, interpreted the data, and helped to draft the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Project administration|Writing - Original Draft	YES
5328894	28244030	TK	2	performed the experiments and the data analysis	performed the experiments and the data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5328894	28244030	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5328894	28244030	YS	2	conceived of the study, participated in its design and coordination, and interpreted the data	conceived of the study, participated in its design and coordination, and interpreted the data	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology|Project administration	YES
5761208	29354146	AB	2	supervised the kaspar snp design program|provided scientific expertise on the conception of the study	supervised the kaspar snp design program	Conceived and designed the experiments	Supervision	YES
5761208	29354146	AB	2	supervised the kaspar snp design program|provided scientific expertise on the conception of the study	provided scientific expertise on the conception of the study	Conceived and designed the experiments	Conceptualization	YES
5761208	29354146	AD	2	managed and participated in phenotypic data acquisition, performed all the phenotypic and gwa analyses and drafted the manuscript	managed and participated in phenotypic data acquisition, performed all the phenotypic and gwa analyses and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Formal analysis|Investigation|Writing - Original Draft	YES
5761208	29354146	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5761208	29354146	GA	2	coordinated the snp genotyping of the collection, performed its analysis and contributed to genetic analysis	coordinated the snp genotyping of the collection, performed its analysis and contributed to genetic analysis	Performed the experiments	Investigation|Project administration	YES
5761208	29354146	GB	2	coordinated the snp genotyping of the collection, performed its analysis and contributed to genetic analysis|supervised the kaspar snp design program	coordinated the snp genotyping of the collection, performed its analysis and contributed to genetic analysis	Performed the experiments	Investigation|Project administration	YES
5761208	29354146	GB	2	coordinated the snp genotyping of the collection, performed its analysis and contributed to genetic analysis|supervised the kaspar snp design program	supervised the kaspar snp design program	Conceived and designed the experiments	Supervision	YES
5761208	29354146	GD	2	provided scientific expertise on the conception of the study	provided scientific expertise on the conception of the study	Conceived and designed the experiments	Conceptualization	YES
5761208	29354146	GLR	2	contributed to implement controlled condition assays, evaluated plant architecture and disease resistance traits and analyzed root images	contributed to implement controlled condition assays, evaluated plant architecture and disease resistance traits and analyzed root images	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
5761208	29354146	HM	2	contributed to implement controlled condition assays, evaluated plant architecture and disease resistance traits and analyzed root images	contributed to implement controlled condition assays, evaluated plant architecture and disease resistance traits and analyzed root images	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
5761208	29354146	HdL	2	contributed to implement controlled condition assays, evaluated plant architecture and disease resistance traits and analyzed root images	contributed to implement controlled condition assays, evaluated plant architecture and disease resistance traits and analyzed root images	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
5761208	29354146	Infinium BeadChip	2	genotyping program of the pea-collection	genotyping program of the pea-collection	Performed the experiments	Investigation	YES
5761208	29354146	JB	2	provided scientific expertise on the conception of the study	provided scientific expertise on the conception of the study	Conceived and designed the experiments	Conceptualization	YES
5761208	29354146	M-LP	2	coordinated the overall study and the manuscript draft	coordinated the overall study and the manuscript draft	Wrote the paper	Project administration|Writing - Original Draft	YES
5761208	29354146	MM-D	2	co-supervised the conception of the study and the drafting of the manuscript	co-supervised the conception of the study and the drafting of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Supervision|Writing - Original Draft	YES
5761208	29354146	VA	2	contributed to implement controlled condition assays, evaluated plant architecture and disease resistance traits and analyzed root images	contributed to implement controlled condition assays, evaluated plant architecture and disease resistance traits and analyzed root images	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
5761208	29354146	VB	2	coordinated the overall study and the manuscript draft	coordinated the overall study and the manuscript draft	Wrote the paper	Project administration|Writing - Original Draft	YES
5761208	29354146	VNB	2	contributed to implement controlled condition assays, evaluated plant architecture and disease resistance traits and analyzed root images	contributed to implement controlled condition assays, evaluated plant architecture and disease resistance traits and analyzed root images	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
4609182	26254305	GK	2	purified parkin and performed nmr titrations	purified parkin and performed nmr titrations	Performed the experiments	Investigation	YES
4609182	26254305	JW	2	did x-ray data processing and phasing	did x-ray data processing and phasing	Analyzed the data	Data curation	YES
4609182	26254305	KG	2	conceived experiments, performed data analysis, and wrote the manuscript	conceived experiments, performed data analysis, and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
4609182	26254305	MS	2	purified parkin and performed nmr titrations	purified parkin and performed nmr titrations	Performed the experiments	Investigation	YES
4609182	26254305	MV	2	performed the ubiquitination assay	performed the ubiquitination assay	Performed the experiments	Investigation	YES
4609182	26254305	SAXS	2	data acquisition, itc assays, pull-down assays, and wrote the manuscript|data acquisition, and itc assays	data acquisition, itc assays, pull-down assays, and wrote the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4609182	26254305	SAXS	2	data acquisition, itc assays, pull-down assays, and wrote the manuscript|data acquisition, and itc assays	data acquisition, and itc assays	Performed the experiments	Investigation	YES
4609182	26254305	SR	2	did the kinase assays	did the kinase assays	Performed the experiments	Investigation	YES
4609182	26254305	TS	2	performed nmr titrations and analysis	performed nmr titrations and analysis	Performed the experiments	Investigation	YES
4609182	26254305	VS	2	performed construct design, protein purifications	performed construct design, protein purifications	Conceived and designed the experiments|Performed the experiments	Investigation	YES
1937019	17710142	BB	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1937019	17710142	BB	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1937019	17710142	CT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1937019	17710142	CT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1937019	17710142	CT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1937019	17710142	CT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1937019	17710142	FC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1937019	17710142	FC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1937019	17710142	FC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1937019	17710142	FC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1937019	17710142	FC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1937019	17710142	FL	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1937019	17710142	FL	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1937019	17710142	HT	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1937019	17710142	HT	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1937019	17710142	PV	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1937019	17710142	PV	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5105234	27843418	BJF	2	assisted in study design, participant recruitment, and data analyses	assisted in study design, participant recruitment, and data analyses	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5105234	27843418	BMK	2	assisted in study design, participant recruitment, and data analyses|performed data collection|drafted the first version of the manuscript	assisted in study design, participant recruitment, and data analyses	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5105234	27843418	BMK	2	assisted in study design, participant recruitment, and data analyses|performed data collection|drafted the first version of the manuscript	performed data collection	Performed the experiments	Investigation	YES
5105234	27843418	BMK	2	assisted in study design, participant recruitment, and data analyses|performed data collection|drafted the first version of the manuscript	drafted the first version of the manuscript	Wrote the paper	Writing - Original Draft	YES
5105234	27843418	JAR	2	performed data collection	performed data collection	Performed the experiments	Investigation	YES
5105234	27843418	JWS	2	assisted in study design, participant recruitment, and data analyses|was responsible for securing research funding|drafted the first version of the manuscript	assisted in study design, participant recruitment, and data analyses	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5105234	27843418	JWS	2	assisted in study design, participant recruitment, and data analyses|was responsible for securing research funding|drafted the first version of the manuscript	was responsible for securing research funding	-	Funding acquisition	YES
5105234	27843418	JWS	2	assisted in study design, participant recruitment, and data analyses|was responsible for securing research funding|drafted the first version of the manuscript	drafted the first version of the manuscript	Wrote the paper	Writing - Original Draft	YES
5105234	27843418	MJM	2	assisted in study design, participant recruitment, and data analyses|drafted the first version of the manuscript	assisted in study design, participant recruitment, and data analyses	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5105234	27843418	MJM	2	assisted in study design, participant recruitment, and data analyses|drafted the first version of the manuscript	drafted the first version of the manuscript	Wrote the paper	Writing - Original Draft	YES
5105234	27843418	PJF	2	assisted in study design, participant recruitment, and data analyses	assisted in study design, participant recruitment, and data analyses	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5105234	27843418	TJP	2	performed data collection	performed data collection	Performed the experiments	Investigation	YES
5680785	29121865	AK	2	conceived the study|were responsible for data analysis, interpretation, and writing the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5680785	29121865	AK	2	conceived the study|were responsible for data analysis, interpretation, and writing the manuscript	were responsible for data analysis, interpretation, and writing the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5680785	29121865	AS-V	2	conceived the study|supervised processing of raw rna seq reads and initial rna seq analysis|were responsible for bioinformatics analysis and interpretation of rna seq data|contributed to tissue collection|were responsible for data analysis, interpretation, and writing the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5680785	29121865	AS-V	2	conceived the study|supervised processing of raw rna seq reads and initial rna seq analysis|were responsible for bioinformatics analysis and interpretation of rna seq data|contributed to tissue collection|were responsible for data analysis, interpretation, and writing the manuscript	supervised processing of raw rna seq reads and initial rna seq analysis	Performed the experiments	Investigation|Supervision	YES
5680785	29121865	AS-V	2	conceived the study|supervised processing of raw rna seq reads and initial rna seq analysis|were responsible for bioinformatics analysis and interpretation of rna seq data|contributed to tissue collection|were responsible for data analysis, interpretation, and writing the manuscript	were responsible for bioinformatics analysis and interpretation of rna seq data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5680785	29121865	AS-V	2	conceived the study|supervised processing of raw rna seq reads and initial rna seq analysis|were responsible for bioinformatics analysis and interpretation of rna seq data|contributed to tissue collection|were responsible for data analysis, interpretation, and writing the manuscript	contributed to tissue collection	Contributed reagents/materials/analysis tools	Resources	YES
5680785	29121865	AS-V	2	conceived the study|supervised processing of raw rna seq reads and initial rna seq analysis|were responsible for bioinformatics analysis and interpretation of rna seq data|contributed to tissue collection|were responsible for data analysis, interpretation, and writing the manuscript	were responsible for data analysis, interpretation, and writing the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5680785	29121865	JAC	2	contributed to data analysis and interpretation, and to the writing of the manuscript	contributed to data analysis and interpretation, and to the writing of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5680785	29121865	KWL	2	supervised processing of raw rna seq reads and initial rna seq analysis|were responsible for bioinformatics analysis and interpretation of rna seq data|performed the phenotypic validation experiments|contributed to tissue collection|were responsible for data analysis, interpretation, and writing the manuscript	supervised processing of raw rna seq reads and initial rna seq analysis	Performed the experiments	Investigation|Supervision	YES
5680785	29121865	KWL	2	supervised processing of raw rna seq reads and initial rna seq analysis|were responsible for bioinformatics analysis and interpretation of rna seq data|performed the phenotypic validation experiments|contributed to tissue collection|were responsible for data analysis, interpretation, and writing the manuscript	were responsible for bioinformatics analysis and interpretation of rna seq data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5680785	29121865	KWL	2	supervised processing of raw rna seq reads and initial rna seq analysis|were responsible for bioinformatics analysis and interpretation of rna seq data|performed the phenotypic validation experiments|contributed to tissue collection|were responsible for data analysis, interpretation, and writing the manuscript	performed the phenotypic validation experiments	Performed the experiments	Investigation|Validation	YES
5680785	29121865	KWL	2	supervised processing of raw rna seq reads and initial rna seq analysis|were responsible for bioinformatics analysis and interpretation of rna seq data|performed the phenotypic validation experiments|contributed to tissue collection|were responsible for data analysis, interpretation, and writing the manuscript	contributed to tissue collection	Contributed reagents/materials/analysis tools	Resources	YES
5680785	29121865	KWL	2	supervised processing of raw rna seq reads and initial rna seq analysis|were responsible for bioinformatics analysis and interpretation of rna seq data|performed the phenotypic validation experiments|contributed to tissue collection|were responsible for data analysis, interpretation, and writing the manuscript	were responsible for data analysis, interpretation, and writing the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5680785	29121865	PEK	2	conceived the study|were responsible for bioinformatics analysis and interpretation of rna seq data|adapted the decalcification protocol to zebrafish heads and was responsible for the laser microdissection of experimental tissue and rna isolation for sequencing|were responsible for data analysis, interpretation, and writing the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5680785	29121865	PEK	2	conceived the study|were responsible for bioinformatics analysis and interpretation of rna seq data|adapted the decalcification protocol to zebrafish heads and was responsible for the laser microdissection of experimental tissue and rna isolation for sequencing|were responsible for data analysis, interpretation, and writing the manuscript	were responsible for bioinformatics analysis and interpretation of rna seq data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5680785	29121865	PEK	2	conceived the study|were responsible for bioinformatics analysis and interpretation of rna seq data|adapted the decalcification protocol to zebrafish heads and was responsible for the laser microdissection of experimental tissue and rna isolation for sequencing|were responsible for data analysis, interpretation, and writing the manuscript	adapted the decalcification protocol to zebrafish heads and was responsible for the laser microdissection of experimental tissue and rna isolation for sequencing	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5680785	29121865	PEK	2	conceived the study|were responsible for bioinformatics analysis and interpretation of rna seq data|adapted the decalcification protocol to zebrafish heads and was responsible for the laser microdissection of experimental tissue and rna isolation for sequencing|were responsible for data analysis, interpretation, and writing the manuscript	were responsible for data analysis, interpretation, and writing the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4415910	25928807	DW	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415910	25928807	DW	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415910	25928807	DW	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415910	25928807	ET	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415910	25928807	ET	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415910	25928807	ET	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415910	25928807	ET	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415910	25928807	JH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415910	25928807	JH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415910	25928807	JH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415910	25928807	JH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415910	25928807	JH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415910	25928807	NF	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415910	25928807	NF	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415910	25928807	NF	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415910	25928807	SH	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415910	25928807	SH	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415910	25928807	SH	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415910	25928807	SH	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4232928	24797664	All authors	2	gave input, reviewed and approved the manuscript	gave input, reviewed and approved the manuscript	Wrote the paper	Writing - Review & Editing	YES
1937020	17710143	BG	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1937020	17710143	BG	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1937020	17710143	GS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1937020	17710143	GS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1937020	17710143	GS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1937020	17710143	RW	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5766665	29358942	AR	2	conceived the study and obtained the funding|participated to designing the genetic tests, providing the seed and establishing and maintaining tests on the field	conceived the study and obtained the funding	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
5766665	29358942	AR	2	conceived the study and obtained the funding|participated to designing the genetic tests, providing the seed and establishing and maintaining tests on the field	participated to designing the genetic tests, providing the seed and establishing and maintaining tests on the field	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5766665	29358942	All authors	2	participated in the drafting of the manuscript|read and approved the final version of the manuscript	participated in the drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
5766665	29358942	All authors	2	participated in the drafting of the manuscript|read and approved the final version of the manuscript	read and approved the final version of the manuscript	-	-	NO
5766665	29358942	GO	2	performed traits measurements, data analyses and primary interpretation of results	performed traits measurements, data analyses and primary interpretation of results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5766665	29358942	JBe	2	conceived the study and obtained the funding	conceived the study and obtained the funding	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
5766665	29358942	JBo	2	conceived the study and obtained the funding	conceived the study and obtained the funding	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
5766665	29358942	JD	2	participated in the statistical analyses	participated in the statistical analyses	Analyzed the data	Formal analysis	YES
5766665	29358942	LB	2	conceived the study and obtained the funding	conceived the study and obtained the funding	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
5766665	29358942	ML	2	conceived the study and obtained the funding|his team installed the three weather stations for the acquisition of environmental data, and conducted mineral and root architecture analyses	conceived the study and obtained the funding	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
5766665	29358942	ML	2	conceived the study and obtained the funding|his team installed the three weather stations for the acquisition of environmental data, and conducted mineral and root architecture analyses	his team installed the three weather stations for the acquisition of environmental data, and conducted mineral and root architecture analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5328899	28244029	AF	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5328899	28244029	All	PLoS52	animal experiments and study protocols were approved by the guidelines of the zhejiang university animal care and use committee	animal experiments and study protocols were approved by the guidelines of the zhejiang university animal care and use committee	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5328899	28244029	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5328899	28244029	BW	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5328899	28244029	The authors	PLoS52	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5328899	28244029	WL	PLoS52	conceived and designed the experiments|revised the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5328899	28244029	WL	PLoS52	conceived and designed the experiments|revised the paper	revised the paper	Wrote the paper	Writing - Review & Editing	YES
5328899	28244029	XC	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5328899	28244029	YL	PLoS52	revised the paper	revised the paper	Wrote the paper	Writing - Review & Editing	YES
5328899	28244029	YW	PLoS52	conceived and designed the experiments|performed the experiments|performed the experiments|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5328899	28244029	YW	PLoS52	conceived and designed the experiments|performed the experiments|performed the experiments|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5328899	28244029	YW	PLoS52	conceived and designed the experiments|performed the experiments|performed the experiments|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5328899	28244029	YW	PLoS52	conceived and designed the experiments|performed the experiments|performed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
1937021	17684556	AF	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1937021	17684556	EW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1937021	17684556	EW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1937021	17684556	EW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1937021	17684556	EW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1937021	17684556	PL	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5680815	29121857	All authors	2	read, revised and approved the final manuscript	read, revised and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5680815	29121857	BG	2	reference panel and support in high-performance computing	reference panel and support in high-performance computing	Performed the experiments	Formal analysis|Investigation	YES
5680815	29121857	HP	2	designed the experiments|imputed and analyzed the sequence data|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5680815	29121857	HP	2	designed the experiments|imputed and analyzed the sequence data|wrote the manuscript	imputed and analyzed the sequence data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5680815	29121857	HP	2	designed the experiments|imputed and analyzed the sequence data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5680815	29121857	MEG	2	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
4609183	26254304	AK	2	crystallized and solved the ublr0rbr and s65dr0rbr structures, performed the complex experiments in fig 6 , analysed data and wrote the manuscript|produced phosphoproteins	crystallized and solved the ublr0rbr and s65dr0rbr structures, performed the complex experiments in fig 6 , analysed data and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4609183	26254304	AK	2	crystallized and solved the ublr0rbr and s65dr0rbr structures, performed the complex experiments in fig 6 , analysed data and wrote the manuscript|produced phosphoproteins	produced phosphoproteins	Performed the experiments	Investigation	YES
4609183	26254304	GSS	2	conceived of the study, designed experiments, analysed data and wrote the manuscript	conceived of the study, designed experiments, analysed data and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
4609183	26254304	HW	2	conceived of the study, designed experiments, analysed data and wrote the manuscript	conceived of the study, designed experiments, analysed data and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
4609183	26254304	KRB	2	expressed and purified numerous isotopically labelled proteins for nmr experiment	expressed and purified numerous isotopically labelled proteins for nmr experiment	Performed the experiments	Investigation	YES
4609183	26254304	NMR	2	spectra of r0rbr	spectra of r0rbr	-	-	NO
4609183	26254304	RJMT	2	performed itc experiments and analysis, and expressed and purified multiple proteins	performed itc experiments and analysis, and expressed and purified multiple proteins	Performed the experiments	Investigation	YES
4609183	26254304	RT	2	cloned several constructs	cloned several constructs	Performed the experiments	Investigation	YES
4609183	26254304	VKC	2	designed and performed ubiquitination assays	designed and performed ubiquitination assays	Conceived and designed the experiments|Performed the experiments	Investigation	YES
4415911	25927356	CMC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415911	25927356	DQL	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415911	25927356	DQL	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415911	25927356	GHD	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415911	25927356	GYL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415911	25927356	HC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4415911	25927356	JSL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415911	25927356	JW	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415911	25927356	MHS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4415911	25927356	QXH	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415911	25927356	WTY	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4415911	25927356	X. Hu	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4415911	25927356	X. Huang	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415911	25927356	X. Yan	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4415911	25927356	X. Yang	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415911	25927356	X. Yang	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415911	25927356	X. Yang	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415911	25927356	X. Yang	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415911	25927356	XJX	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4415911	25927356	XJX	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4415911	25927356	XYZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4415911	25927356	YFH	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415911	25927356	YYC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4415911	25927356	YZ	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4415911	25927356	YZ	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4415911	25927356	YZG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4415911	25927356	Z. Shao	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415911	25927356	Z. Shen	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415911	25927356	ZBL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415911	25927356	ZGC	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4415911	25927356	ZH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415911	25927356	ZH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415911	25927356	ZH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415911	25927356	ZH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5767183	29375597	AE-G	2	performed the measurements of 8-ohg level including isolation of mrna	performed the measurements of 8-ohg level including isolation of mrna	Performed the experiments	Investigation	YES
5767183	29375597	All authors	2	analyzed the obtained results|critically read, corrected, and approved the manuscript	analyzed the obtained results	Analyzed the data	Formal analysis	YES
5767183	29375597	All authors	2	analyzed the obtained results|critically read, corrected, and approved the manuscript	critically read, corrected, and approved the manuscript	Wrote the paper	Writing - Review & Editing	YES
5767183	29375597	JC-B	2	designed the research|performed the measurements of 8-ohg level including isolation of mrna|carried out the examination of lipid peroxidation|wrote the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
5767183	29375597	JC-B	2	designed the research|performed the measurements of 8-ohg level including isolation of mrna|carried out the examination of lipid peroxidation|wrote the manuscript	performed the measurements of 8-ohg level including isolation of mrna	Performed the experiments	Investigation	YES
5767183	29375597	JC-B	2	designed the research|performed the measurements of 8-ohg level including isolation of mrna|carried out the examination of lipid peroxidation|wrote the manuscript	carried out the examination of lipid peroxidation	Performed the experiments	Investigation	YES
5767183	29375597	JC-B	2	designed the research|performed the measurements of 8-ohg level including isolation of mrna|carried out the examination of lipid peroxidation|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5767183	29375597	JD	2	designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
5767183	29375597	MB	2	performed the measurements of 8-ohg level including isolation of mrna	performed the measurements of 8-ohg level including isolation of mrna	Performed the experiments	Investigation	YES
5767183	29375597	RNA	2	mrna isolation	mrna isolation	Performed the experiments	Investigation	YES
1937022	17710153	GZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1937022	17710153	MC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1937022	17710153	MC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1937022	17710153	MC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1937022	17710153	RF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1937022	17710153	RF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1937022	17710153	RF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1937022	17710153	RF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5328902	28244031	AW	2	supervised the work and helped prepare the manuscript	supervised the work and helped prepare the manuscript	Wrote the paper	Supervision|Writing - Original Draft	YES
5328902	28244031	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5328902	28244031	DP	2	developed the hypothesis, supervised the whole work and prepared the manuscript	developed the hypothesis, supervised the whole work and prepared the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Supervision|Writing - Original Draft	YES
5328902	28244031	JL	2	developed the hypothesis, supervised the whole work and prepared the manuscript	developed the hypothesis, supervised the whole work and prepared the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Supervision|Writing - Original Draft	YES
5328902	28244031	LC	2	designed and worked on the bench as well as drafted manuscript	designed and worked on the bench as well as drafted manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Writing - Original Draft	YES
5328902	28244031	QY	2	designed and worked on the bench as well as drafted manuscript	designed and worked on the bench as well as drafted manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Writing - Original Draft	YES
5328902	28244031	SY	2	designed and worked on the bench as well as drafted manuscript	designed and worked on the bench as well as drafted manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Writing - Original Draft	YES
5328902	28244031	XT	2	supervised the work and helped prepare the manuscript	supervised the work and helped prepare the manuscript	Wrote the paper	Supervision|Writing - Original Draft	YES
5328902	28244031	XY	2	designed and worked on the bench as well as drafted manuscript	designed and worked on the bench as well as drafted manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Writing - Original Draft	YES
5121944	27924137	AC	2	wrote the main manuscript text	wrote the main manuscript text	Wrote the paper	Writing - Original Draft	YES
5121944	27924137	All authors	2	read, provided feedback and approved the final version	read, provided feedback and approved the final version	-	-	NO
5121944	27924137	NM	2	designed, coordinated, provided critical revision of the article and prepared all figures	designed, coordinated, provided critical revision of the article and prepared all figures	Conceived and designed the experiments|Wrote the paper	Project administration|Visualization|Writing - Review & Editing	YES
5680825	29121877	BH	2	provided useful comments and suggestions and helped to draft the manuscript	provided useful comments and suggestions and helped to draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5680825	29121877	HJM	2	conceived and designed the study|provided useful comments and suggestions and helped to draft the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5680825	29121877	HJM	2	conceived and designed the study|provided useful comments and suggestions and helped to draft the manuscript	provided useful comments and suggestions and helped to draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5680825	29121877	MAMG	2	conceived and designed the study|provided useful comments and suggestions and helped to draft the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5680825	29121877	MAMG	2	conceived and designed the study|provided useful comments and suggestions and helped to draft the manuscript	provided useful comments and suggestions and helped to draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5680825	29121877	MB	2	performed the data analysis|provided useful comments and suggestions and helped to draft the manuscript	performed the data analysis	Analyzed the data	Formal analysis	YES
5680825	29121877	MB	2	performed the data analysis|provided useful comments and suggestions and helped to draft the manuscript	provided useful comments and suggestions and helped to draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5680825	29121877	MFLD	2	performed the data analysis|wrote the manuscript	performed the data analysis	Analyzed the data	Formal analysis	YES
5680825	29121877	MFLD	2	performed the data analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5680825	29121877	MSL	2	provided useful comments and suggestions and helped to draft the manuscript	provided useful comments and suggestions and helped to draft the manuscript	Wrote the paper	Writing - Original Draft	YES
1937023	17710136	JG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1937023	17710136	JG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1937023	17710136	JG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1937023	17710136	MJ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1937023	17710136	MW	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4619914	26539549	D. Pfalzgraf	2	equally contributed to this paper	equally contributed to this paper	-	-	NO
4619914	26539549	M. Ritter	2	equally contributed to this paper	equally contributed to this paper	-	-	NO
4415912	25927835	JEK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415912	25927835	JEK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415912	25927835	JEK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415912	25927835	JEK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415912	25927835	KLR	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415912	25927835	KLR	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415912	25927835	LB	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415912	25927835	LS	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415912	25927835	MJ	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415912	25927835	MJ	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415912	25927835	SDR	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415912	25927835	SDR	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5767185	29375601	H-QY	PLoS52	revised the article	revised the article	Wrote the paper	Writing - Review & Editing	YES
5767185	29375601	HL	PLoS52	conceived and designed the work|analyzed the data|wrote the article	conceived and designed the work	Conceived and designed the experiments	Conceptualization	YES
5767185	29375601	HL	PLoS52	conceived and designed the work|analyzed the data|wrote the article	analyzed the data	Analyzed the data	Formal analysis	YES
5767185	29375601	HL	PLoS52	conceived and designed the work|analyzed the data|wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
5767185	29375601	JC	PLoS52	revised the article	revised the article	Wrote the paper	Writing - Review & Editing	YES
5767185	29375601	PX	PLoS52	conceived and designed the work|carried out the experiments|analyzed the data|revised the article	conceived and designed the work	Conceived and designed the experiments	Conceptualization	YES
5767185	29375601	PX	PLoS52	conceived and designed the work|carried out the experiments|analyzed the data|revised the article	carried out the experiments	Performed the experiments	Investigation	YES
5767185	29375601	PX	PLoS52	conceived and designed the work|carried out the experiments|analyzed the data|revised the article	analyzed the data	Analyzed the data	Formal analysis	YES
5767185	29375601	PX	PLoS52	conceived and designed the work|carried out the experiments|analyzed the data|revised the article	revised the article	Wrote the paper	Writing - Review & Editing	YES
5767185	29375601	SW	PLoS52	helped with constructing some clones	helped with constructing some clones	Performed the experiments	Investigation	YES
5767185	29375601	TZ	PLoS52	conceived and designed the work|carried out the experiments|analyzed the data|wrote the article	conceived and designed the work	Conceived and designed the experiments	Conceptualization	YES
5767185	29375601	TZ	PLoS52	conceived and designed the work|carried out the experiments|analyzed the data|wrote the article	carried out the experiments	Performed the experiments	Investigation	YES
5767185	29375601	TZ	PLoS52	conceived and designed the work|carried out the experiments|analyzed the data|wrote the article	analyzed the data	Analyzed the data	Formal analysis	YES
5767185	29375601	TZ	PLoS52	conceived and designed the work|carried out the experiments|analyzed the data|wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
5767185	29375601	WW	PLoS52	helped with constructing some clones	helped with constructing some clones	Performed the experiments	Investigation	YES
4654935	26471730	AI	2	supervised the ase function under|planned experiments and analysed results	supervised the ase function under	-	Supervision	YES
4654935	26471730	AI	2	supervised the ase function under|planned experiments and analysed results	planned experiments and analysed results	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
4654935	26471730	BDD	2	assisted with mass spectrometry analysis under	assisted with mass spectrometry analysis under	Performed the experiments	Investigation	YES
4654935	26471730	CK	2	performed most of the experiments|planned experiments and analysed results	performed most of the experiments	Performed the experiments	Investigation	YES
4654935	26471730	CK	2	performed most of the experiments|planned experiments and analysed results	planned experiments and analysed results	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
4654935	26471730	DGC	2	assisted with mass spectrometry analysis under	assisted with mass spectrometry analysis under	Performed the experiments	Investigation	YES
4654935	26471730	GTPase	2	function under	function under	-	-	NO
4654935	26471730	HIW	2	performed biochemical analysis of pink1	performed biochemical analysis of pink1	Performed the experiments	Investigation	YES
4654935	26471730	JBP	2	performed bioinformatic analysis	performed bioinformatic analysis	Performed the experiments	Formal analysis|Investigation	YES
4654935	26471730	JCC	2	generated and provided pink1 patient fibroblasts	generated and provided pink1 patient fibroblasts	Performed the experiments	Investigation	YES
4654935	26471730	MMKM	2	planned experiments and analysed results|wrote the paper with|conceived and supervised the project	planned experiments and analysed results	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
4654935	26471730	MMKM	2	planned experiments and analysed results|wrote the paper with|conceived and supervised the project	wrote the paper with	Wrote the paper	Writing - Original Draft	YES
4654935	26471730	MMKM	2	planned experiments and analysed results|wrote the paper with|conceived and supervised the project	conceived and supervised the project	Conceived and designed the experiments	Conceptualization|Supervision	YES
4654935	26471730	MP	2	generated cdna constructs used in the project	generated cdna constructs used in the project	Performed the experiments	Investigation	YES
4654935	26471730	MT	2	supervised the assisted with mass spectrometry analysis under|planned experiments and analysed results|conceived and supervised the project	supervised the assisted with mass spectrometry analysis under	Performed the experiments	Investigation|Supervision	YES
4654935	26471730	MT	2	supervised the assisted with mass spectrometry analysis under|planned experiments and analysed results|conceived and supervised the project	planned experiments and analysed results	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
4654935	26471730	MT	2	supervised the assisted with mass spectrometry analysis under|planned experiments and analysed results|conceived and supervised the project	conceived and supervised the project	Conceived and designed the experiments	Conceptualization|Supervision	YES
4654935	26471730	OC	2	generated and provided pink1 patient fibroblasts	generated and provided pink1 patient fibroblasts	Performed the experiments	Investigation	YES
4654935	26471730	RG	2	assisted with mass spectrometry analysis under	assisted with mass spectrometry analysis under	Performed the experiments	Investigation	YES
4654935	26471730	TJM	2	designed and generated cas9/crispr oligos	designed and generated cas9/crispr oligos	Conceived and designed the experiments|Performed the experiments	Investigation	YES
4654935	26471730	YCL	2	performed most of the experiments|planned experiments and analysed results|wrote the paper with	performed most of the experiments	Performed the experiments	Investigation	YES
4654935	26471730	YCL	2	performed most of the experiments|planned experiments and analysed results|wrote the paper with	planned experiments and analysed results	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
4654935	26471730	YCL	2	performed most of the experiments|planned experiments and analysed results|wrote the paper with	wrote the paper with	Wrote the paper	Writing - Original Draft	YES
4654935	26471730	all the authors	2	contributed with the wrote the paper with	contributed with the wrote the paper with	Wrote the paper	Writing - Original Draft	YES
5121981	27904439	FF	2	both participated in literature review and drafting the letter	both participated in literature review and drafting the letter	Wrote the paper	Formal analysis|Writing - Original Draft	YES
5121981	27904439	NM	2	both participated in literature review and drafting the letter	both participated in literature review and drafting the letter	Wrote the paper	Formal analysis|Writing - Original Draft	YES
4619918	26539548	Kaori Umezaki	2	contributed equally	contributed equally	-	-	NO
4619918	26539548	Tomoki Nishimura	2	contributed equally	contributed equally	-	-	NO
5331024	28247289	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5331024	28247289	MJK	PLoS52	conceived anddesigned the study|performed the experiments|analyzed the data|wrote the manuscript	conceived anddesigned the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5331024	28247289	MJK	PLoS52	conceived anddesigned the study|performed the experiments|analyzed the data|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5331024	28247289	MJK	PLoS52	conceived anddesigned the study|performed the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5331024	28247289	MJK	PLoS52	conceived anddesigned the study|performed the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5331024	28247289	MO	PLoS52	advised the research	advised the research	-	-	NO
5331024	28247289	MRR	PLoS52	conceived anddesigned the study|performed the experiments|analyzed the data|revised the manuscript	conceived anddesigned the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5331024	28247289	MRR	PLoS52	conceived anddesigned the study|performed the experiments|analyzed the data|revised the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5331024	28247289	MRR	PLoS52	conceived anddesigned the study|performed the experiments|analyzed the data|revised the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5331024	28247289	MRR	PLoS52	conceived anddesigned the study|performed the experiments|analyzed the data|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5331024	28247289	SDS	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5331024	28247289	SI	PLoS52	advised the research	advised the research	-	-	NO
1937024	17710124	CE	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1937024	17710124	DU	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1937024	17710124	FL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1937024	17710124	FM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1937024	17710124	GM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1937024	17710124	JF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1937024	17710124	JF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1937024	17710124	JF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1937024	17710124	MC	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1937024	17710124	MC	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1937024	17710124	MH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1937024	17710124	MO	PLoS5	Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1937024	17710124	MO	PLoS5	Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1937024	17710124	RT	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1937024	17710124	RT	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1937024	17710124	TI	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1937024	17710124	TT	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1937024	17710124	TT	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1937024	17710124	WF	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415913	25928218	CFM	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415913	25928218	CMF	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4415913	25928218	EI	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415913	25928218	EI	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415913	25928218	EM	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415913	25928218	EM	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415913	25928218	JPD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415913	25928218	JPD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415913	25928218	JPD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415913	25928218	JS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4415913	25928218	JS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415913	25928218	KA	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415913	25928218	KA	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415913	25928218	KSS	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415913	25928218	KSS	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415913	25928218	KSS	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415913	25928218	PDC	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415913	25928218	PDC	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415913	25928218	RSK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415913	25928218	RSK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415913	25928218	RSK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415913	25928218	SP	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415913	25928218	SP	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5767223	29375599	JY	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5767223	29375599	LH	PLoS52	supervised the research	supervised the research	-	Supervision	YES
5767223	29375599	PS	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5767223	29375599	WG	PLoS52	wrote the manuscript|supervised the research	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5767223	29375599	WG	PLoS52	wrote the manuscript|supervised the research	supervised the research	-	Supervision	YES
5767223	29375599	YiZ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5767223	29375599	YuZ	PLoS52	wrote the manuscript|performed the experiments	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5767223	29375599	YuZ	PLoS52	wrote the manuscript|performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5681780	29126398	DJZ	PLoS52	conceived and designed the experiments|performed the data analyses|wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5681780	29126398	DJZ	PLoS52	conceived and designed the experiments|performed the data analyses|wrote the manuscript	performed the data analyses	Analyzed the data	Formal analysis	YES
5681780	29126398	DJZ	PLoS52	conceived and designed the experiments|performed the data analyses|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5681780	29126398	DYZ	PLoS52	conceived and designed the experiments|supervised the study|wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5681780	29126398	DYZ	PLoS52	conceived and designed the experiments|supervised the study|wrote the manuscript	supervised the study	-	Supervision	YES
5681780	29126398	DYZ	PLoS52	conceived and designed the experiments|supervised the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5681780	29126398	EP	PLoS52	contributed to the concept development|wrote the manuscript	contributed to the concept development	Conceived and designed the experiments	Conceptualization	YES
5681780	29126398	EP	PLoS52	contributed to the concept development|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5681780	29126398	HL	PLoS52	contributed to the concept development|wrote the manuscript	contributed to the concept development	Conceived and designed the experiments	Conceptualization	YES
5681780	29126398	HL	PLoS52	contributed to the concept development|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5681780	29126398	ML	PLoS52	contributed to the concept development|wrote the manuscript	contributed to the concept development	Conceived and designed the experiments	Conceptualization	YES
5681780	29126398	ML	PLoS52	contributed to the concept development|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5123227	27924138	AJM	4	The study was designed by|Funding was obtained by|data were collected and analyzed by|data interpretation and manuscript preparation were undertaken by	The study was designed by	Conceived and designed the experiments	Methodology	YES
5123227	27924138	AJM	4	The study was designed by|Funding was obtained by|data were collected and analyzed by|data interpretation and manuscript preparation were undertaken by	Funding was obtained by	-	Funding acquisition	YES
5123227	27924138	AJM	4	The study was designed by|Funding was obtained by|data were collected and analyzed by|data interpretation and manuscript preparation were undertaken by	data were collected and analyzed by	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5123227	27924138	AJM	4	The study was designed by|Funding was obtained by|data were collected and analyzed by|data interpretation and manuscript preparation were undertaken by	data interpretation and manuscript preparation were undertaken by	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5123227	27924138	JLK	4	The study was designed by|Funding was obtained by|data were collected and analyzed by|data interpretation and manuscript preparation were undertaken by	The study was designed by	Conceived and designed the experiments	Methodology	YES
5123227	27924138	JLK	4	The study was designed by|Funding was obtained by|data were collected and analyzed by|data interpretation and manuscript preparation were undertaken by	Funding was obtained by	-	Funding acquisition	YES
5123227	27924138	JLK	4	The study was designed by|Funding was obtained by|data were collected and analyzed by|data interpretation and manuscript preparation were undertaken by	data were collected and analyzed by	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5123227	27924138	JLK	4	The study was designed by|Funding was obtained by|data were collected and analyzed by|data interpretation and manuscript preparation were undertaken by	data interpretation and manuscript preparation were undertaken by	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5123227	27924138	MJO	4	The study was designed by|data interpretation and manuscript preparation were undertaken by	The study was designed by	Conceived and designed the experiments	Methodology	YES
5123227	27924138	MJO	4	The study was designed by|data interpretation and manuscript preparation were undertaken by	data interpretation and manuscript preparation were undertaken by	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4682641	26438724	LG	2	assisted with data analysis and establishment of the methods	assisted with data analysis and establishment of the methods	Performed the experiments|Analyzed the data	Formal analysis	YES
4682641	26438724	MAK	2	assisted with data analysis and establishment of the methods	assisted with data analysis and establishment of the methods	Performed the experiments|Analyzed the data	Formal analysis	YES
4682641	26438724	MB	2	obtained funding, designed experiments, and oversaw the study|wrote the manuscript	obtained funding, designed experiments, and oversaw the study	Conceived and designed the experiments	Funding acquisition|Methodology|Supervision	YES
4682641	26438724	MB	2	obtained funding, designed experiments, and oversaw the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4682641	26438724	RK-S	2	performed chip, generated libraries for next-generation sequencing, and analyzed chip-seq	performed chip, generated libraries for next-generation sequencing, and analyzed chip-seq	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4682641	26438724	RNA	2	deep sequencing	deep sequencing	Performed the experiments	Investigation	YES
4682641	26438724	RS	2	designed and carried out most of the experiments|wrote the manuscript	designed and carried out most of the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4682641	26438724	RS	2	designed and carried out most of the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
1937025	17710139	RB	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1937025	17710139	TK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1937025	17710139	TK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1937025	17710139	TK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4415914	25927437	DH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415914	25927437	DH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415914	25927437	DH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415914	25927437	ERL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4415914	25927437	FR	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4415914	25927437	GE	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415914	25927437	GE	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4415914	25927437	JAJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415914	25927437	JAJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4415914	25927437	JAJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4415914	25927437	KS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415914	25927437	KS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415914	25927437	KS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415914	25927437	KS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415914	25927437	LSB	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415914	25927437	NRB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5413861	28160316	CR	2	contributed to the study design, collected the data and co-ordinated the study|planned and conducted the data analysis	contributed to the study design, collected the data and co-ordinated the study	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Project administration|Resources	YES
5413861	28160316	CR	2	contributed to the study design, collected the data and co-ordinated the study|planned and conducted the data analysis	planned and conducted the data analysis	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
5413861	28160316	IJH	2	acting as senior researcher	acting as senior researcher	-	-	NO
5413861	28160316	JMD	2	planned and conducted the data analysis|prepared the manuscript with all other authors providing comments and critical revisions	planned and conducted the data analysis	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
5413861	28160316	JMD	2	planned and conducted the data analysis|prepared the manuscript with all other authors providing comments and critical revisions	prepared the manuscript with all other authors providing comments and critical revisions	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5413861	28160316	TRO	2	contributed to the study design, collected the data and co-ordinated the study	contributed to the study design, collected the data and co-ordinated the study	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Project administration|Resources	YES
5413861	28160316	all authors	2	prior to submission	prior to submission	-	-	NO
5334330	28255861	JC	1	Analysis	Analysis	-	-	NO
5334330	28255861	MI	1	Drafting	Drafting	Wrote the paper	Writing - Original Draft	YES
5334330	28255861	TA	1	Experimentation	Experimentation	Performed the experiments	Investigation	YES
5334330	28255861	XZ	1	Analysis	Analysis	-	-	NO
5334330	28255861	YW	1	Planning and designing of study	Planning and designing of study	Conceived and designed the experiments	Methodology	YES
5767231	29375608	AN	1	Experimental design|Data analysis|Manuscript preparation|Supervision, funding, and reagents	Experimental design	Conceived and designed the experiments	Methodology	YES
5767231	29375608	AN	1	Experimental design|Data analysis|Manuscript preparation|Supervision, funding, and reagents	Data analysis	Analyzed the data	Formal analysis	YES
5767231	29375608	AN	1	Experimental design|Data analysis|Manuscript preparation|Supervision, funding, and reagents	Manuscript preparation	Wrote the paper	Writing - Original Draft	YES
5767231	29375608	AN	1	Experimental design|Data analysis|Manuscript preparation|Supervision, funding, and reagents	Supervision, funding, and reagents	-	Funding acquisition|Supervision	YES
5767231	29375608	K-SC	1	Experimental design|Experiments|Data analysis|Manuscript preparation	Experimental design	Conceived and designed the experiments	Methodology	YES
5767231	29375608	K-SC	1	Experimental design|Experiments|Data analysis|Manuscript preparation	Experiments	-	-	NO
5767231	29375608	K-SC	1	Experimental design|Experiments|Data analysis|Manuscript preparation	Data analysis	Analyzed the data	Formal analysis	YES
5767231	29375608	K-SC	1	Experimental design|Experiments|Data analysis|Manuscript preparation	Manuscript preparation	Wrote the paper	Writing - Original Draft	YES
5767231	29375608	KT	1	Experiments|Data analysis|Manuscript preparation	Experiments	-	-	NO
5767231	29375608	KT	1	Experiments|Data analysis|Manuscript preparation	Data analysis	Analyzed the data	Formal analysis	YES
5767231	29375608	KT	1	Experiments|Data analysis|Manuscript preparation	Manuscript preparation	Wrote the paper	Writing - Original Draft	YES
5767231	29375608	NK	1	Experimental design|Manuscript preparation|Supervision, funding, and reagents	Experimental design	Conceived and designed the experiments	Methodology	YES
5767231	29375608	NK	1	Experimental design|Manuscript preparation|Supervision, funding, and reagents	Manuscript preparation	Wrote the paper	Writing - Original Draft	YES
5767231	29375608	NK	1	Experimental design|Manuscript preparation|Supervision, funding, and reagents	Supervision, funding, and reagents	-	Funding acquisition|Supervision	YES
5126823	27932937	BB	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5126823	27932937	DJC	PLoS52	designed the research|supervised the research nurse coordinators and phlebotomists in the implementation of the study|edited the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
5126823	27932937	DJC	PLoS52	designed the research|supervised the research nurse coordinators and phlebotomists in the implementation of the study|edited the manuscript	supervised the research nurse coordinators and phlebotomists in the implementation of the study	Performed the experiments	Investigation|Project administration|Supervision	YES
5126823	27932937	DJC	PLoS52	designed the research|supervised the research nurse coordinators and phlebotomists in the implementation of the study|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5126823	27932937	GF	PLoS52	designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
5126823	27932937	JAS	PLoS52	edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5126823	27932937	JJW	PLoS52	designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
5126823	27932937	REH	PLoS52	designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
5681832	29126393	AD	2	generated and provided data on the laboratory characteristics of the clinical and environmental strains	generated and provided data on the laboratory characteristics of the clinical and environmental strains	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5681832	29126393	DB	2	performed ngs sequencing and part of the ngs data analysis	performed ngs sequencing and part of the ngs data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5681832	29126393	DD	2	provided epidemiological data on the patients movements and environmental isolates	provided epidemiological data on the patients movements and environmental isolates	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5681832	29126393	JL	2	provided epidemiological data on the patients movements and environmental isolates	provided epidemiological data on the patients movements and environmental isolates	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5681832	29126393	LS	2	performed ngs sequencing and part of the ngs data analysis	performed ngs sequencing and part of the ngs data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5681832	29126393	MM	2	generated and provided data on the laboratory characteristics of the clinical and environmental strains	generated and provided data on the laboratory characteristics of the clinical and environmental strains	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5681832	29126393	MW	2	designed the study, analysed the data and prepared the manuscript	designed the study, analysed the data and prepared the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5681832	29126393	PO	2	performed ngs sequencing and part of the ngs data analysis	performed ngs sequencing and part of the ngs data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5681832	29126393	SO	2	performed ngs sequencing and part of the ngs data analysis	performed ngs sequencing and part of the ngs data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5681832	29126393	SP	2	designed the study, analysed the data and prepared the manuscript	designed the study, analysed the data and prepared the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5681832	29126393	WV	2	provided epidemiological data on the patients movements and environmental isolates	provided epidemiological data on the patients movements and environmental isolates	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
1937026	17710150	DN	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1937026	17710150	DN	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1937026	17710150	HP	PLoS5	Discussion of methods|Discussion of results and editing of manuscript	Discussion of methods	Performed the experiments	-	YES
1937026	17710150	HP	PLoS5	Discussion of methods|Discussion of results and editing of manuscript	Discussion of results and editing of manuscript	Wrote the paper	Writing - Review & Editing	YES
1937026	17710150	IC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1937026	17710150	IC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1937026	17710150	IC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1937026	17710150	PA	PLoS5	Discussion of results and editing of manuscript	Discussion of results and editing of manuscript	Wrote the paper	Writing - Review & Editing	YES
1937026	17710150	PM	PLoS5	Discussion of results and editing of manuscript	Discussion of results and editing of manuscript	Wrote the paper	Writing - Review & Editing	YES
1937026	17710150	TM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1937026	17710150	TM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1937026	17710150	TM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1937026	17710150	TM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4717998	26620550	CAS	2	wrote the manuscript|designed, performed, and analyzed cell-biological experiments|designed, performed, and analyzed animal experiments	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4717998	26620550	CAS	2	wrote the manuscript|designed, performed, and analyzed cell-biological experiments|designed, performed, and analyzed animal experiments	designed, performed, and analyzed cell-biological experiments	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
4717998	26620550	CAS	2	wrote the manuscript|designed, performed, and analyzed cell-biological experiments|designed, performed, and analyzed animal experiments	designed, performed, and analyzed animal experiments	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
4717998	26620550	JBR	2	designed, performed, and analyzed animal experiments	designed, performed, and analyzed animal experiments	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
4717998	26620550	KN	2	designed, performed, and analyzed cell-biological experiments	designed, performed, and analyzed cell-biological experiments	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
4717998	26620550	NH	2	designed, performed, and analyzed animal experiments	designed, performed, and analyzed animal experiments	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
4717998	26620550	SFT	2	conceived the project and supervised all research|wrote the manuscript	conceived the project and supervised all research	Conceived and designed the experiments	Conceptualization|Supervision	YES
4717998	26620550	SFT	2	conceived the project and supervised all research|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4415915	25927985	HTP	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4415915	25927985	LZ	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4415915	25927985	LZ	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415915	25927985	MZZ	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4415915	25927985	TTW	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415915	25927985	TTW	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415915	25927985	TTW	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415915	25927985	YLG	PLoS5	Conceived and designed the experiments|Wrote the paper|Obtained permission for use of rats	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415915	25927985	YLG	PLoS5	Conceived and designed the experiments|Wrote the paper|Obtained permission for use of rats	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415915	25927985	YLG	PLoS5	Conceived and designed the experiments|Wrote the paper|Obtained permission for use of rats	Obtained permission for use of rats	-	-	NO
5139084	27980499	AA	2	conceived the study|participated in the design and coordination of the study|carried out the data collection and performed the statistical analysis|helped to draft the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5139084	27980499	AA	2	conceived the study|participated in the design and coordination of the study|carried out the data collection and performed the statistical analysis|helped to draft the manuscript	participated in the design and coordination of the study	Conceived and designed the experiments	Methodology|Project administration	YES
5139084	27980499	AA	2	conceived the study|participated in the design and coordination of the study|carried out the data collection and performed the statistical analysis|helped to draft the manuscript	carried out the data collection and performed the statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5139084	27980499	AA	2	conceived the study|participated in the design and coordination of the study|carried out the data collection and performed the statistical analysis|helped to draft the manuscript	helped to draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5139084	27980499	AF	2	participated in the design and coordination of the study	participated in the design and coordination of the study	Conceived and designed the experiments	Methodology|Project administration	YES
5139084	27980499	JO	2	conceived the study|participated in the design and coordination of the study|carried out the data collection and performed the statistical analysis|helped to draft the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5139084	27980499	JO	2	conceived the study|participated in the design and coordination of the study|carried out the data collection and performed the statistical analysis|helped to draft the manuscript	participated in the design and coordination of the study	Conceived and designed the experiments	Methodology|Project administration	YES
5139084	27980499	JO	2	conceived the study|participated in the design and coordination of the study|carried out the data collection and performed the statistical analysis|helped to draft the manuscript	carried out the data collection and performed the statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5139084	27980499	JO	2	conceived the study|participated in the design and coordination of the study|carried out the data collection and performed the statistical analysis|helped to draft the manuscript	helped to draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5139084	27980499	KRM	2	carried out blood analyses	carried out blood analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5767233	29375600	DC-D	2	edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5767233	29375600	DN	2	organized and wrote the manuscript	organized and wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4415916	25927209	AIDC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415916	25927209	AIDC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415916	25927209	AIDC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415916	25927209	AIDC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415916	25927209	JC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415916	25927209	RE	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415916	25927209	RE	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415916	25927209	RE	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415916	25927209	RP	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415916	25927209	SB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5339260	28265975	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5339260	28265975	BSM	2	assisted with the experiments	assisted with the experiments	Performed the experiments	Investigation	YES
5339260	28265975	DOS	2	assisted with the experiments	assisted with the experiments	Performed the experiments	Investigation	YES
5339260	28265975	JMS	2	designed research|performed research|analyzed data and wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
5339260	28265975	JMS	2	designed research|performed research|analyzed data and wrote the paper	performed research	Performed the experiments	Investigation	YES
5339260	28265975	JMS	2	designed research|performed research|analyzed data and wrote the paper	analyzed data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5339260	28265975	LFPS	2	designed research|analyzed data and wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
5339260	28265975	LFPS	2	designed research|analyzed data and wrote the paper	analyzed data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5339260	28265975	LGM	2	assisted partly with laboratory analysis	assisted partly with laboratory analysis	Performed the experiments	Investigation	YES
5339260	28265975	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
1937027	17710151	AG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1937027	17710151	AG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1937027	17710151	AG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1937027	17710151	AG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1937027	17710151	AG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1937027	17710151	ASG	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1937027	17710151	ASG	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1937027	17710151	SW	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1937027	17710151	SW	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5681842	29126384	LM	2	designed the project|analyzed data|interpreted data analysis results|wrote the manuscript|edited the manuscript	designed the project	Conceived and designed the experiments	Methodology	YES
5681842	29126384	LM	2	designed the project|analyzed data|interpreted data analysis results|wrote the manuscript|edited the manuscript	analyzed data	Analyzed the data	Formal analysis	YES
5681842	29126384	LM	2	designed the project|analyzed data|interpreted data analysis results|wrote the manuscript|edited the manuscript	interpreted data analysis results	Analyzed the data	Formal analysis	YES
5681842	29126384	LM	2	designed the project|analyzed data|interpreted data analysis results|wrote the manuscript|edited the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5681842	29126384	LM	2	designed the project|analyzed data|interpreted data analysis results|wrote the manuscript|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5681842	29126384	MC	2	analyzed data|edited the manuscript	analyzed data	Analyzed the data	Formal analysis	YES
5681842	29126384	MC	2	analyzed data|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5681842	29126384	WS	2	designed the project|interpreted data analysis results|edited the manuscript	designed the project	Conceived and designed the experiments	Methodology	YES
5681842	29126384	WS	2	designed the project|interpreted data analysis results|edited the manuscript	interpreted data analysis results	Analyzed the data	Formal analysis	YES
5681842	29126384	WS	2	designed the project|interpreted data analysis results|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5681842	29126384	YF	2	analyzed data|wrote the manuscript	analyzed data	Analyzed the data	Formal analysis	YES
5681842	29126384	YF	2	analyzed data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4741301	26711178	APS	2	performed the mass spectrometry analysis of the bioid experiments	performed the mass spectrometry analysis of the bioid experiments	Performed the experiments	Investigation	YES
4741301	26711178	CAL	2	designed and performed most of the experiments and wrote the manuscript	designed and performed most of the experiments and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
4741301	26711178	CB	2	generated the stable shrna cells and provided reagents and advice	generated the stable shrna cells and provided reagents and advice	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4741301	26711178	DF	2	performed the mass spectrometry analysis of the bioid experiments	performed the mass spectrometry analysis of the bioid experiments	Performed the experiments	Investigation	YES
4741301	26711178	DJ	2	performed the atg9 immunoisolation experiments	performed the atg9 immunoisolation experiments	Performed the experiments	Investigation	YES
4741301	26711178	SAT	2	directed the research, performed the gst pulldown in fig 1 and wrote the manuscript	directed the research, performed the gst pulldown in fig 1 and wrote the manuscript	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Original Draft	YES
4741301	26711178	SN	2	generated the stable shrna cells and provided reagents and advice	generated the stable shrna cells and provided reagents and advice	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5223470	28077934	CHH	4	data were collected and analyzed by	data were collected and analyzed by	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5223470	28077934	DSH	4	The study was designed by|data were collected and analyzed by|data interpretation and manuscript preparation were undertaken by	The study was designed by	Conceived and designed the experiments	Methodology	YES
5223470	28077934	DSH	4	The study was designed by|data were collected and analyzed by|data interpretation and manuscript preparation were undertaken by	data were collected and analyzed by	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5223470	28077934	DSH	4	The study was designed by|data were collected and analyzed by|data interpretation and manuscript preparation were undertaken by	data interpretation and manuscript preparation were undertaken by	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5223470	28077934	SYC	4	The study was designed by|data were collected and analyzed by|data interpretation and manuscript preparation were undertaken by	The study was designed by	Conceived and designed the experiments	Methodology	YES
5223470	28077934	SYC	4	The study was designed by|data were collected and analyzed by|data interpretation and manuscript preparation were undertaken by	data were collected and analyzed by	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5223470	28077934	SYC	4	The study was designed by|data were collected and analyzed by|data interpretation and manuscript preparation were undertaken by	data interpretation and manuscript preparation were undertaken by	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5223470	28077934	TGW	4	The study was designed by	The study was designed by	Conceived and designed the experiments	Methodology	YES
5223470	28077934	WSY	4	The study was designed by|data interpretation and manuscript preparation were undertaken by	The study was designed by	Conceived and designed the experiments	Methodology	YES
5223470	28077934	WSY	4	The study was designed by|data interpretation and manuscript preparation were undertaken by	data interpretation and manuscript preparation were undertaken by	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5767239	29375606	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5767239	29375606	DX	2	designed the research and wrote the manuscript	designed the research and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5767239	29375606	JSun	2	designed the research and wrote the manuscript	designed the research and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
1939728	17710127	AV	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1939728	17710127	AV	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1939728	17710127	BP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1939728	17710127	CD	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1939728	17710127	CD	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1939728	17710127	EH	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1939728	17710127	EH	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1939728	17710127	FB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1939728	17710127	FB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1939728	17710127	FB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1939728	17710127	FB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1939728	17710127	FJ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1939728	17710127	LF	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1939728	17710127	LF	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1939728	17710127	LF	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1939728	17710127	LG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1939728	17710127	MM	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1939728	17710127	MM	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1939728	17710127	OL	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1939728	17710127	OL	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1939728	17710127	PB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1939728	17710127	PK	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1939728	17710127	PK	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1939728	17710127	PL	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1939728	17710127	PL	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1939728	17710127	SH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1939728	17710127	VG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4415917	25927990	AN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415917	25927990	AN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415917	25927990	AN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415917	25927990	AN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415917	25927990	AN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415917	25927990	BR	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415917	25927990	BR	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4415917	25927990	CB	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415917	25927990	CB	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4415917	25927990	CS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415917	25927990	CS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4415917	25927990	CS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415917	25927990	FK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4415917	25927990	KK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4415917	25927990	KK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415917	25927990	KV	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4415917	25927990	LS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4415917	25927990	MA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415917	25927990	MA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415917	25927990	MA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415917	25927990	MA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415917	25927990	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415917	25927990	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415917	25927990	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415917	25927990	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415917	25927990	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5339263	28265976	AB	1	Design of the experiments|Experiments performed by|Data analyses|The article written by|Graphics	Design of the experiments	Conceived and designed the experiments	Methodology	YES
5339263	28265976	AB	1	Design of the experiments|Experiments performed by|Data analyses|The article written by|Graphics	Experiments performed by	Performed the experiments	Investigation	YES
5339263	28265976	AB	1	Design of the experiments|Experiments performed by|Data analyses|The article written by|Graphics	Data analyses	Analyzed the data	Formal analysis	YES
5339263	28265976	AB	1	Design of the experiments|Experiments performed by|Data analyses|The article written by|Graphics	The article written by	Wrote the paper	Writing - Original Draft	YES
5339263	28265976	AB	1	Design of the experiments|Experiments performed by|Data analyses|The article written by|Graphics	Graphics	-	-	NO
5339263	28265976	JM	1	Design of the experiments|Experiments performed by|Data analyses|The article written by|Graphics	Design of the experiments	Conceived and designed the experiments	Methodology	YES
5339263	28265976	JM	1	Design of the experiments|Experiments performed by|Data analyses|The article written by|Graphics	Experiments performed by	Performed the experiments	Investigation	YES
5339263	28265976	JM	1	Design of the experiments|Experiments performed by|Data analyses|The article written by|Graphics	Data analyses	Analyzed the data	Formal analysis	YES
5339263	28265976	JM	1	Design of the experiments|Experiments performed by|Data analyses|The article written by|Graphics	The article written by	Wrote the paper	Writing - Original Draft	YES
5339263	28265976	JM	1	Design of the experiments|Experiments performed by|Data analyses|The article written by|Graphics	Graphics	-	-	NO
5339263	28265976	JRM	1	Design of the experiments|Experiments performed by|Data analyses|The article written by	Design of the experiments	Conceived and designed the experiments	Methodology	YES
5339263	28265976	JRM	1	Design of the experiments|Experiments performed by|Data analyses|The article written by	Experiments performed by	Performed the experiments	Investigation	YES
5339263	28265976	JRM	1	Design of the experiments|Experiments performed by|Data analyses|The article written by	Data analyses	Analyzed the data	Formal analysis	YES
5339263	28265976	JRM	1	Design of the experiments|Experiments performed by|Data analyses|The article written by	The article written by	Wrote the paper	Writing - Original Draft	YES
5339263	28265976	KR	1	Design of the experiments|Experiments performed by|Data analyses|The article written by|Graphics	Design of the experiments	Conceived and designed the experiments	Methodology	YES
5339263	28265976	KR	1	Design of the experiments|Experiments performed by|Data analyses|The article written by|Graphics	Experiments performed by	Performed the experiments	Investigation	YES
5339263	28265976	KR	1	Design of the experiments|Experiments performed by|Data analyses|The article written by|Graphics	Data analyses	Analyzed the data	Formal analysis	YES
5339263	28265976	KR	1	Design of the experiments|Experiments performed by|Data analyses|The article written by|Graphics	The article written by	Wrote the paper	Writing - Original Draft	YES
5339263	28265976	KR	1	Design of the experiments|Experiments performed by|Data analyses|The article written by|Graphics	Graphics	-	-	NO
5767242	29375603	H-CW	2	contributed the experimental design, research fund and critical revising of the manuscript	contributed the experimental design, research fund and critical revising of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
5767242	29375603	J-WY	2	performed the field experiments and lab analyses and contributed draft writing	performed the field experiments and lab analyses and contributed draft writing	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5767242	29375603	W-PS	2	performed the field experiments and lab analyses and contributed draft writing	performed the field experiments and lab analyses and contributed draft writing	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5767242	29375603	WC	2	performed the field experiments and lab analyses and contributed draft writing	performed the field experiments and lab analyses and contributed draft writing	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5767242	29375603	X-MH	2	contributed the experimental design, research fund and critical revising of the manuscript	contributed the experimental design, research fund and critical revising of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
5682641	29132317	AL	CRediT	Conceived and designed the experiments|Performed the experiments|Analysed the data|Writing - draft	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5682641	29132317	AL	CRediT	Conceived and designed the experiments|Performed the experiments|Analysed the data|Writing - draft	Performed the experiments	Performed the experiments	Investigation	YES
5682641	29132317	AL	CRediT	Conceived and designed the experiments|Performed the experiments|Analysed the data|Writing - draft	Analysed the data	Analyzed the data	Formal analysis	YES
5682641	29132317	AL	CRediT	Conceived and designed the experiments|Performed the experiments|Analysed the data|Writing - draft	Writing - draft	Wrote the paper	Writing - Original Draft	YES
5682641	29132317	CK	CRediT	Conceived and designed the experiments|Performed the experiments|Writing - review & editing	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5682641	29132317	CK	CRediT	Conceived and designed the experiments|Performed the experiments|Writing - review & editing	Performed the experiments	Performed the experiments	Investigation	YES
5682641	29132317	CK	CRediT	Conceived and designed the experiments|Performed the experiments|Writing - review & editing	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
5682641	29132317	CM	CRediT	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5682641	29132317	IB	CRediT	Supervised field work and responsible for acquisition of samples	Supervised field work and responsible for acquisition of samples	Performed the experiments	Investigation|Supervision	YES
5682641	29132317	IF	CRediT	Conceived and designed the experiments|Supervision|Writing - draft	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5682641	29132317	IF	CRediT	Conceived and designed the experiments|Supervision|Writing - draft	Supervision	-	Supervision	YES
5682641	29132317	IF	CRediT	Conceived and designed the experiments|Supervision|Writing - draft	Writing - draft	Wrote the paper	Writing - Original Draft	YES
5682641	29132317	IM	CRediT	Conceived and designed the experiments|Supervision|Writing - review & editing	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5682641	29132317	IM	CRediT	Conceived and designed the experiments|Supervision|Writing - review & editing	Supervision	-	Supervision	YES
5682641	29132317	IM	CRediT	Conceived and designed the experiments|Supervision|Writing - review & editing	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
5682641	29132317	JHK	CRediT	Performed the experiments|Writing - review & editing	Performed the experiments	Performed the experiments	Investigation	YES
5682641	29132317	JHK	CRediT	Performed the experiments|Writing - review & editing	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
5682641	29132317	LOC	CRediT	Supervision|Writing - review & editing	Supervision	-	Supervision	YES
5682641	29132317	LOC	CRediT	Supervision|Writing - review & editing	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
5682641	29132317	NH	CRediT	Performed the experiments|Writing - review & editing	Performed the experiments	Performed the experiments	Investigation	YES
5682641	29132317	NH	CRediT	Performed the experiments|Writing - review & editing	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
5682641	29132317	SW	CRediT	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5682641	29132317	SW	CRediT	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1939729	17684553	EC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1939729	17684553	EC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1939729	17684553	EC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1939729	17684553	FC	PLoS5	Conceived and designed the experiments|Wrote the paper|Medical director	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1939729	17684553	FC	PLoS5	Conceived and designed the experiments|Wrote the paper|Medical director	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1939729	17684553	FC	PLoS5	Conceived and designed the experiments|Wrote the paper|Medical director	Medical director	-	-	NO
1939729	17684553	FR	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1939729	17684553	FR	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1939729	17684553	FT	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1939729	17684553	FT	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1939729	17684553	SB	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1939729	17684553	SB	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1939729	17684553	SP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Had full access to all the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1939729	17684553	SP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Had full access to all the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis	Analyzed the data	Analyzed the data	Formal analysis	YES
1939729	17684553	SP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Had full access to all the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1939729	17684553	SP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Had full access to all the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis	Had full access to all the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis	Analyzed the data	Data curation|Formal analysis	YES
4620037	26539488	Jie Chen	2	contributed equally to this work	contributed equally to this work	-	-	NO
4620037	26539488	Yanzhou Yang	2	contributed equally to this work	contributed equally to this work	-	-	NO
4741303	26742780	ACB	2	designed and supervised experiments	designed and supervised experiments	Conceived and designed the experiments	Methodology|Supervision	YES
4741303	26742780	ADH	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
4741303	26742780	AMC	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
4741303	26742780	AMS	2	conceived the study, designed and supervised experiments, and wrote the paper	conceived the study, designed and supervised experiments, and wrote the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Supervision|Writing - Original Draft	YES
4741303	26742780	All authors	2	edited the paper	edited the paper	Wrote the paper	Writing - Review & Editing	YES
4741303	26742780	CM	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
4741303	26742780	CMS	2	designed and supervised experiments	designed and supervised experiments	Conceived and designed the experiments	Methodology|Supervision	YES
4741303	26742780	CXCS	2	designed and performed experiments, analyzed data, and wrote the paper	designed and performed experiments, analyzed data, and wrote the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4741303	26742780	DF	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
4741303	26742780	DM	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
4741303	26742780	EB	2	designed and supervised experiments	designed and supervised experiments	Conceived and designed the experiments	Methodology|Supervision	YES
4741303	26742780	JK	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
4741303	26742780	KS	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
4741303	26742780	MB	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
4741303	26742780	MP	2	designed and supervised experiments	designed and supervised experiments	Conceived and designed the experiments	Methodology|Supervision	YES
4741303	26742780	MZ	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
4741303	26742780	MZS	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
4741303	26742780	NA	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
4741303	26742780	RAS	2	designed and supervised experiments	designed and supervised experiments	Conceived and designed the experiments	Methodology|Supervision	YES
4741303	26742780	RC	2	designed and supervised experiments	designed and supervised experiments	Conceived and designed the experiments	Methodology|Supervision	YES
4741303	26742780	RCH	2	designed and supervised experiments	designed and supervised experiments	Conceived and designed the experiments	Methodology|Supervision	YES
4741303	26742780	RPB	2	designed and supervised experiments	designed and supervised experiments	Conceived and designed the experiments	Methodology|Supervision	YES
4741303	26742780	TVM	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
4741303	26742780	VB	2	designed and supervised experiments	designed and supervised experiments	Conceived and designed the experiments	Methodology|Supervision	YES
5234097	28096757	CPE	2	served as a scientific liaison to the sponsor, assisted in study design, data analysis and interpretation, and provided comments on the manuscript|was not involved in data collection or data entry and there were no restrictions on publication of the data or preparation of this paper	served as a scientific liaison to the sponsor, assisted in study design, data analysis and interpretation, and provided comments on the manuscript	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5234097	28096757	CPE	2	served as a scientific liaison to the sponsor, assisted in study design, data analysis and interpretation, and provided comments on the manuscript|was not involved in data collection or data entry and there were no restrictions on publication of the data or preparation of this paper	was not involved in data collection or data entry and there were no restrictions on publication of the data or preparation of this paper	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5234097	28096757	DW	2	assisted in data collection and sample analysis	assisted in data collection and sample analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5234097	28096757	MG	2	assisted in research design and consultation	assisted in research design and consultation	Conceived and designed the experiments	-	YES
5234097	28096757	MK	2	assisted in data collection and sample analysis	assisted in data collection and sample analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5234097	28096757	NB	2	assisted in data collection and sample analysis	assisted in data collection and sample analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5234097	28096757	PI	2	assisted in the design of the study, data analysis, and manuscript preparation	assisted in the design of the study, data analysis, and manuscript preparation	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5234097	28096757	PSM	2	served as study quality assurance manager	served as study quality assurance manager	Performed the experiments	Project administration|Validation	YES
5234097	28096757	YPJ	2	served as study coordinator and assisted with data collection, data analysis, and manuscript preparation	served as study coordinator and assisted with data collection, data analysis, and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Project administration|Writing - Original Draft	YES
5342990	28275994	All authors	2	participated in the discussion of the experiment schedule and problem at regular intervals in the whole processes of this study|read and approved the final manuscript	participated in the discussion of the experiment schedule and problem at regular intervals in the whole processes of this study	Performed the experiments	Investigation	YES
5342990	28275994	All authors	2	participated in the discussion of the experiment schedule and problem at regular intervals in the whole processes of this study|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5342990	28275994	TH	2	participated in the design of the study, coordination and helped to draft the manuscript	participated in the design of the study, coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft	YES
5342990	28275994	YB	2	conceived of this microbial induced carbonate precipitation studies, participated in the whole experiments, samples scanning, data analysis and drafted the manuscript	conceived of this microbial induced carbonate precipitation studies, participated in the whole experiments, samples scanning, data analysis and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
5342990	28275994	YZL	2	participated in the sequence alignment	participated in the sequence alignment	Performed the experiments	Investigation	YES
5767251	29375607	JK	2	conducted the confocal microscopy	conducted the confocal microscopy	Performed the experiments	Investigation	YES
5767251	29375607	KC	2	planned the experiments, analyzed the data and wrote the article	planned the experiments, analyzed the data and wrote the article	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
5767251	29375607	PR	2	carried out all the experiments|planned the experiments, analyzed the data and wrote the article	carried out all the experiments	Performed the experiments	Investigation	YES
5767251	29375607	PR	2	carried out all the experiments|planned the experiments, analyzed the data and wrote the article	planned the experiments, analyzed the data and wrote the article	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
5767251	29375607	YG	2	carried out all the experiments	carried out all the experiments	Performed the experiments	Investigation	YES
4415918	25928421	AV	PLoS5	Contributed to analysis and interpretation of data|Revised the manuscript critically	Contributed to analysis and interpretation of data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
4415918	25928421	AV	PLoS5	Contributed to analysis and interpretation of data|Revised the manuscript critically	Revised the manuscript critically	Wrote the paper	Writing - Review & Editing	YES
4415918	25928421	CT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed and developed the model|Contributed to analysis and interpretation of data|Wrote the first draft of the manuscript|Revised the manuscript critically	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415918	25928421	CT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed and developed the model|Contributed to analysis and interpretation of data|Wrote the first draft of the manuscript|Revised the manuscript critically	Analyzed the data	Analyzed the data	Formal analysis	YES
4415918	25928421	CT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed and developed the model|Contributed to analysis and interpretation of data|Wrote the first draft of the manuscript|Revised the manuscript critically	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415918	25928421	CT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed and developed the model|Contributed to analysis and interpretation of data|Wrote the first draft of the manuscript|Revised the manuscript critically	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415918	25928421	CT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed and developed the model|Contributed to analysis and interpretation of data|Wrote the first draft of the manuscript|Revised the manuscript critically	Designed and developed the model	Conceived and designed the experiments|Performed the experiments	Methodology	YES
4415918	25928421	CT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed and developed the model|Contributed to analysis and interpretation of data|Wrote the first draft of the manuscript|Revised the manuscript critically	Contributed to analysis and interpretation of data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
4415918	25928421	CT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed and developed the model|Contributed to analysis and interpretation of data|Wrote the first draft of the manuscript|Revised the manuscript critically	Wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
4415918	25928421	CT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed and developed the model|Contributed to analysis and interpretation of data|Wrote the first draft of the manuscript|Revised the manuscript critically	Revised the manuscript critically	Wrote the paper	Writing - Review & Editing	YES
4415918	25928421	GB	PLoS5	Contributed to analysis and interpretation of data|Revised the manuscript critically	Contributed to analysis and interpretation of data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
4415918	25928421	GB	PLoS5	Contributed to analysis and interpretation of data|Revised the manuscript critically	Revised the manuscript critically	Wrote the paper	Writing - Review & Editing	YES
4415918	25928421	GG	PLoS5	Conceived and designed the experiments|Contributed to analysis and interpretation of data|Revised the manuscript critically	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415918	25928421	GG	PLoS5	Conceived and designed the experiments|Contributed to analysis and interpretation of data|Revised the manuscript critically	Contributed to analysis and interpretation of data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
4415918	25928421	GG	PLoS5	Conceived and designed the experiments|Contributed to analysis and interpretation of data|Revised the manuscript critically	Revised the manuscript critically	Wrote the paper	Writing - Review & Editing	YES
4415918	25928421	RG	PLoS5	Wrote the paper|Contributed to analysis and interpretation of data|Revised the manuscript critically	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415918	25928421	RG	PLoS5	Wrote the paper|Contributed to analysis and interpretation of data|Revised the manuscript critically	Contributed to analysis and interpretation of data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
4415918	25928421	RG	PLoS5	Wrote the paper|Contributed to analysis and interpretation of data|Revised the manuscript critically	Revised the manuscript critically	Wrote the paper	Writing - Review & Editing	YES
4415918	25928421	SF	PLoS5	Contributed reagents/materials/analysis tools|Contributed to analysis and interpretation of data|Revised the manuscript critically	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415918	25928421	SF	PLoS5	Contributed reagents/materials/analysis tools|Contributed to analysis and interpretation of data|Revised the manuscript critically	Contributed to analysis and interpretation of data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
4415918	25928421	SF	PLoS5	Contributed reagents/materials/analysis tools|Contributed to analysis and interpretation of data|Revised the manuscript critically	Revised the manuscript critically	Wrote the paper	Writing - Review & Editing	YES
1939730	17710129	AR	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1939730	17710129	JM	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1939730	17710129	JM	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1939730	17710129	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1939730	17710129	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1939730	17710129	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1939730	17710129	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1939730	17710129	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1939730	17710129	PW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1939730	17710129	PW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1939730	17710129	PW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1939730	17710129	PW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1939730	17710129	RS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1939730	17710129	RS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1939730	17710129	SK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1939730	17710129	SN	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1939730	17710129	SN	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1939730	17710129	XF	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1939730	17710129	XF	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5682865	29132293	EHW	2	assisted with analyses	assisted with analyses	Analyzed the data	Formal analysis	YES
5682865	29132293	JCMD	2	assisted with preparation of the manuscript, oversaw analyses, aided with interpretation of results, and helped conceive the study	assisted with preparation of the manuscript, oversaw analyses, aided with interpretation of results, and helped conceive the study	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Supervision|Writing - Original Draft	YES
5682865	29132293	JKL	2	helped conceive the study	helped conceive the study	Conceived and designed the experiments	Conceptualization	YES
5682865	29132293	JRD	2	wrote the manuscript, conducted analyses, and interpreted results	wrote the manuscript, conducted analyses, and interpreted results	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5682865	29132293	MAK	2	collected samples for the experimental co-infection trials and helped with the design of the trials	collected samples for the experimental co-infection trials and helped with the design of the trials	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5682865	29132293	MCN	2	collected samples for the experimental co-infection trials	collected samples for the experimental co-infection trials	Performed the experiments	Investigation	YES
5682865	29132293	NVLS	2	assisted with analyses and interpretation of results	assisted with analyses and interpretation of results	Analyzed the data	Formal analysis	YES
5682865	29132293	RRR	2	led the co-infection trials and helped conceive the study	led the co-infection trials and helped conceive the study	Conceived and designed the experiments	Conceptualization	YES
5682865	29132293	ZW	2	assisted with analyses	assisted with analyses	Analyzed the data	Formal analysis	YES
4741304	26675138	AT	2	generated the cmyc null	generated the cmyc null	Performed the experiments	Investigation	YES
4741304	26675138	GM	2	conceived the study and carried out, analysed and interpreted experiments	conceived the study and carried out, analysed and interpreted experiments	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation	YES
4741304	26675138	RS	2	generated the cmyc null	generated the cmyc null	Performed the experiments	Investigation	YES
5234109	28096758	CPE	2	served as a scientific liaison to the sponsor, assisted in study design, data analysis and interpretation, and provided comments on the manuscript|was not involved in data collection or data entry and there were no restrictions on publication of the data or preparation of this paper	served as a scientific liaison to the sponsor, assisted in study design, data analysis and interpretation, and provided comments on the manuscript	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5234109	28096758	CPE	2	served as a scientific liaison to the sponsor, assisted in study design, data analysis and interpretation, and provided comments on the manuscript|was not involved in data collection or data entry and there were no restrictions on publication of the data or preparation of this paper	was not involved in data collection or data entry and there were no restrictions on publication of the data or preparation of this paper	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5234109	28096758	DW	2	assisted in data collection and sample analysis	assisted in data collection and sample analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5234109	28096758	EG	2	assisted in data collection and sample analysis	assisted in data collection and sample analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5234109	28096758	MG	2	assisted in research design and consultation	assisted in research design and consultation	Conceived and designed the experiments	-	YES
5234109	28096758	MK	2	assisted in data collection and sample analysis	assisted in data collection and sample analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5234109	28096758	PI	2	assisted in the design of the study, data analysis, and manuscript preparation	assisted in the design of the study, data analysis, and manuscript preparation	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5234109	28096758	PSM	2	served as study quality assurance manager	served as study quality assurance manager	Performed the experiments	Project administration|Validation	YES
5234109	28096758	RD	2	assisted in data collection and sample analysis	assisted in data collection and sample analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5234109	28096758	YPJ	2	served as study coordinator and assisted with data collection, data analysis, and manuscript preparation	served as study coordinator and assisted with data collection, data analysis, and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Project administration|Writing - Original Draft	YES
4415919	25928068	CKA	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415919	25928068	CY	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4415919	25928068	EK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4415919	25928068	JC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415919	25928068	JC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4415919	25928068	JC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4415919	25928068	JC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415919	25928068	JP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415919	25928068	JP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415919	25928068	JP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415919	25928068	JP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415919	25928068	KR	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4415919	25928068	KR	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4415919	25928068	MAL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415919	25928068	ML	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4415919	25928068	SL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415919	25928068	SL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415919	25928068	SL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5767255	29375609	GH	PLoS52	designed and conducted the experiments|performed the experiments|wrote the manuscript	designed and conducted the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5767255	29375609	GH	PLoS52	designed and conducted the experiments|performed the experiments|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5767255	29375609	GH	PLoS52	designed and conducted the experiments|performed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5767255	29375609	HC	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5767255	29375609	HT	PLoS52	designed and conducted the experiments|wrote the manuscript	designed and conducted the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5767255	29375609	HT	PLoS52	designed and conducted the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5767255	29375609	JT	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5767255	29375609	KF	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5767255	29375609	KK	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
1939731	17710131	AH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1939731	17710131	AH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1939731	17710131	AH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1939731	17710131	AH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1939731	17710131	GL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1939731	17710131	HH	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1939731	17710131	JF	PLoS5	Performed the experiments|Technical assistance with cell immunostaining and antibodies	Performed the experiments	Performed the experiments	Investigation	YES
1939731	17710131	JF	PLoS5	Performed the experiments|Technical assistance with cell immunostaining and antibodies	Technical assistance with cell immunostaining and antibodies	Performed the experiments	Investigation	YES
1939731	17710131	MB	PLoS5	Performed the experiments|Technical assistance with cell immunostaining and antibodies	Performed the experiments	Performed the experiments	Investigation	YES
1939731	17710131	MB	PLoS5	Performed the experiments|Technical assistance with cell immunostaining and antibodies	Technical assistance with cell immunostaining and antibodies	Performed the experiments	Investigation	YES
1939731	17710131	RC	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1939731	17710131	RC	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1939731	17710131	SC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1939731	17710131	SC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1939731	17710131	SC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1939731	17710131	SC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1939731	17710131	SS	PLoS5	Contributed reagents/materials/analysis tools|Technical assistance with cell immunostaining and antibodies	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1939731	17710131	SS	PLoS5	Contributed reagents/materials/analysis tools|Technical assistance with cell immunostaining and antibodies	Technical assistance with cell immunostaining and antibodies	Performed the experiments	Investigation	YES
5342995	28275995	AM	2	conceived the study and analyzed and interpreted the results and wrote the paper	conceived the study and analyzed and interpreted the results and wrote the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
5342995	28275995	AT	2	did the esem microscopy work|conceived the study and analyzed and interpreted the results and wrote the paper	did the esem microscopy work	Performed the experiments	Investigation	YES
5342995	28275995	AT	2	did the esem microscopy work|conceived the study and analyzed and interpreted the results and wrote the paper	conceived the study and analyzed and interpreted the results and wrote the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
5342995	28275995	All	2	the data applied in the study are included in the tables and figures presented|the sequences identifies are published in the embl nucleotide sequence database with the accession numbers lt622055-lt622085	the data applied in the study are included in the tables and figures presented	-	Visualization	YES
5342995	28275995	All	2	the data applied in the study are included in the tables and figures presented|the sequences identifies are published in the embl nucleotide sequence database with the accession numbers lt622055-lt622085	the sequences identifies are published in the embl nucleotide sequence database with the accession numbers lt622055-lt622085	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5342995	28275995	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5342995	28275995	DF	2	did the esem microscopy work	did the esem microscopy work	Performed the experiments	Investigation	YES
5342995	28275995	GD	2	did the esem microscopy work	did the esem microscopy work	Performed the experiments	Investigation	YES
5342995	28275995	ML	2	conceived the study and analyzed and interpreted the results and wrote the paper	conceived the study and analyzed and interpreted the results and wrote the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
5342995	28275995	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5342995	28275995	Wind Energy	2	technical university of denmark for access and advice on composite production and physical tests	technical university of denmark for access and advice on composite production and physical tests	-	-	NO
4755111	26783364	CAW	2	performed research|analyzed data	performed research	Performed the experiments	Investigation	YES
4755111	26783364	CAW	2	performed research|analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
4755111	26783364	CB	2	performed research|analyzed data	performed research	Performed the experiments	Investigation	YES
4755111	26783364	CB	2	performed research|analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
4755111	26783364	DCJ	2	performed research|analyzed data|designed the study and coordinated the experimental work	performed research	Performed the experiments	Investigation	YES
4755111	26783364	DCJ	2	performed research|analyzed data|designed the study and coordinated the experimental work	analyzed data	Analyzed the data	Formal analysis	YES
4755111	26783364	DCJ	2	performed research|analyzed data|designed the study and coordinated the experimental work	designed the study and coordinated the experimental work	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Project administration	YES
4755111	26783364	DN	2	performed research	performed research	Performed the experiments	Investigation	YES
4755111	26783364	LG	2	performed research|analyzed data	performed research	Performed the experiments	Investigation	YES
4755111	26783364	LG	2	performed research|analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
4755111	26783364	SJ	2	analyzed data|designed the study and coordinated the experimental work|wrote the manuscript with contributions from all authors	analyzed data	Analyzed the data	Formal analysis	YES
4755111	26783364	SJ	2	analyzed data|designed the study and coordinated the experimental work|wrote the manuscript with contributions from all authors	designed the study and coordinated the experimental work	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Project administration	YES
4755111	26783364	SJ	2	analyzed data|designed the study and coordinated the experimental work|wrote the manuscript with contributions from all authors	wrote the manuscript with contributions from all authors	Wrote the paper	Writing - Original Draft	YES
5683215	29132375	HZC	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5683215	29132375	SZY	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5683215	29132375	WYZ	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|contributed reagents/materials/analysis tools|conceived the experiments and wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5683215	29132375	WYZ	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|contributed reagents/materials/analysis tools|conceived the experiments and wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5683215	29132375	WYZ	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|contributed reagents/materials/analysis tools|conceived the experiments and wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5683215	29132375	WYZ	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|contributed reagents/materials/analysis tools|conceived the experiments and wrote the manuscript	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5683215	29132375	WYZ	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|contributed reagents/materials/analysis tools|conceived the experiments and wrote the manuscript	conceived the experiments and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5683215	29132375	XMT	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5683215	29132375	ZDS	PLoS52	conceived and designed the experiments|contributed reagents/materials/analysis tools|conceived the experiments and wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5683215	29132375	ZDS	PLoS52	conceived and designed the experiments|contributed reagents/materials/analysis tools|conceived the experiments and wrote the manuscript	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5683215	29132375	ZDS	PLoS52	conceived and designed the experiments|contributed reagents/materials/analysis tools|conceived the experiments and wrote the manuscript	conceived the experiments and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5683215	29132375	ZGL	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5683215	29132375	ZYC	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5264320	28138315	AA	2	carried out the data collection|performed the statistical analysis|conceived the study, and participated in its design and coordination|helped to draft the manuscript	carried out the data collection	Performed the experiments	Investigation	YES
5264320	28138315	AA	2	carried out the data collection|performed the statistical analysis|conceived the study, and participated in its design and coordination|helped to draft the manuscript	performed the statistical analysis	Analyzed the data	Formal analysis	YES
5264320	28138315	AA	2	carried out the data collection|performed the statistical analysis|conceived the study, and participated in its design and coordination|helped to draft the manuscript	conceived the study, and participated in its design and coordination	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
5264320	28138315	AA	2	carried out the data collection|performed the statistical analysis|conceived the study, and participated in its design and coordination|helped to draft the manuscript	helped to draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5264320	28138315	AW	2	performed the statistical analysis|helped to draft the manuscript	performed the statistical analysis	Analyzed the data	Formal analysis	YES
5264320	28138315	AW	2	performed the statistical analysis|helped to draft the manuscript	helped to draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5264320	28138315	BHB	2	conceived the study, and participated in its design and coordination	conceived the study, and participated in its design and coordination	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
5264320	28138315	CM	2	carried out the data collection|performed the statistical analysis	carried out the data collection	Performed the experiments	Investigation	YES
5264320	28138315	CM	2	carried out the data collection|performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
5264320	28138315	MJYY	2	carried out the data collection|manufactured the test solutions	carried out the data collection	Performed the experiments	Investigation	YES
5264320	28138315	MJYY	2	carried out the data collection|manufactured the test solutions	manufactured the test solutions	-	-	NO
4415920	25928142	AP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415920	25928142	AP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415920	25928142	AP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415920	25928142	AP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415920	25928142	HvG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4415920	25928142	HvG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415920	25928142	MB	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4415920	25928142	MB	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415920	25928142	PC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4415920	25928142	RB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415920	25928142	RB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415920	25928142	RB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415920	25928142	RB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415920	25928142	RB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5767279	29375602	All authors	2	have read and agree with the contents of the manuscript	have read and agree with the contents of the manuscript	-	-	NO
5767279	29375602	BH	2	designed and led the genomics analyses, population development and genetics analyses, and trait evaluations, respectively	designed and led the genomics analyses, population development and genetics analyses, and trait evaluations, respectively	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5767279	29375602	CP	2	conducted gbs and whole genome shotgun sequencing and bioinformatic analyses	conducted gbs and whole genome shotgun sequencing and bioinformatic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5767279	29375602	JP	2	designed and led the genomics analyses, population development and genetics analyses, and trait evaluations, respectively	designed and led the genomics analyses, population development and genetics analyses, and trait evaluations, respectively	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5767279	29375602	NK	2	designed and led the genomics analyses, population development and genetics analyses, and trait evaluations, respectively	designed and led the genomics analyses, population development and genetics analyses, and trait evaluations, respectively	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5767279	29375602	Q-MG	2	analyzed the data and wrote the paper	analyzed the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5767279	29375602	SR	2	conducted phylogenetic analyses of the candidate genes	conducted phylogenetic analyses of the candidate genes	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5767279	29375602	ST	2	conducted gbs and whole genome shotgun sequencing and bioinformatic analyses	conducted gbs and whole genome shotgun sequencing and bioinformatic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
1939732	17710144	AQ	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1939732	17710144	JB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1939732	17710144	JB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1939732	17710144	JB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1939732	17710144	LG	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1939732	17710144	MK	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5296953	28190980	ACU	2	assisted with data analysis and manuscript preparation	assisted with data analysis and manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5296953	28190980	AYS	2	designed the study, oversaw data collection, data analysis and manuscript preparation	designed the study, oversaw data collection, data analysis and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Supervision|Writing - Original Draft	YES
5296953	28190980	CFB	2	assisted with study design, data analysis and manuscript preparation	assisted with study design, data analysis and manuscript preparation	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5296953	28190980	ICP	2	assisted with designed the study	assisted with designed the study	Conceived and designed the experiments	Methodology	YES
5296953	28190980	LHBF	2	assisted with manuscript design and helped to draft the manuscript	assisted with manuscript design and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
5296953	28190980	RBJ	2	assisted with manuscript preparation and statistical analyzes	assisted with manuscript preparation and statistical analyzes	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5296953	28190980	SRM	2	assisted with data analysis and manuscript preparation	assisted with data analysis and manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5296953	28190980	TSJ	2	assisted with study design, data analysis and manuscript preparation	assisted with study design, data analysis and manuscript preparation	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5683216	29132312	AB	2	contributed representative strains for sequencing and phenotypic data	contributed representative strains for sequencing and phenotypic data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5683216	29132312	All the authors	2	provided intellectual input in finalising the manuscript	provided intellectual input in finalising the manuscript	Wrote the paper	Writing - Review & Editing	YES
5683216	29132312	DS	2	sequenced the strains	sequenced the strains	Performed the experiments	Investigation	YES
5683216	29132312	ECS	2	analysed the sequence data	analysed the sequence data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5683216	29132312	ICS	2	analysed the sequence data	analysed the sequence data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5683216	29132312	JB	2	analysed the sequence data	analysed the sequence data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5683216	29132312	LT	2	conceived and designed the study|contributed representative strains for sequencing and phenotypic data	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5683216	29132312	LT	2	conceived and designed the study|contributed representative strains for sequencing and phenotypic data	contributed representative strains for sequencing and phenotypic data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5683216	29132312	PAH	2	contributed representative strains for sequencing and phenotypic data	contributed representative strains for sequencing and phenotypic data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5683216	29132312	SB	2	analysed the sequence data	analysed the sequence data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5683216	29132312	SG-K	2	cultured the strains and extracted dna for sequencing|analysed the sequence data	cultured the strains and extracted dna for sequencing	Performed the experiments	Investigation	YES
5683216	29132312	SG-K	2	cultured the strains and extracted dna for sequencing|analysed the sequence data	analysed the sequence data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5683216	29132312	VK	2	contributed representative strains for sequencing and phenotypic data	contributed representative strains for sequencing and phenotypic data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5683216	29132312	VS	2	conceived and designed the study|cultured the strains and extracted dna for sequencing|analysed the sequence data|drafted the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5683216	29132312	VS	2	conceived and designed the study|cultured the strains and extracted dna for sequencing|analysed the sequence data|drafted the manuscript	cultured the strains and extracted dna for sequencing	Performed the experiments	Investigation	YES
5683216	29132312	VS	2	conceived and designed the study|cultured the strains and extracted dna for sequencing|analysed the sequence data|drafted the manuscript	analysed the sequence data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5683216	29132312	VS	2	conceived and designed the study|cultured the strains and extracted dna for sequencing|analysed the sequence data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5344870	28281272	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5344870	28281272	BH	2	helped to carry the experiment	helped to carry the experiment	Performed the experiments	Investigation	YES
5344870	28281272	CH	2	helped to carry the experiment	helped to carry the experiment	Performed the experiments	Investigation	YES
5344870	28281272	CS	2	helped to analyze the raw data	helped to analyze the raw data	Analyzed the data	Formal analysis	YES
5344870	28281272	GZ	2	helped to analyze the raw data	helped to analyze the raw data	Analyzed the data	Formal analysis	YES
5344870	28281272	LZ	2	designed the whole experiment	designed the whole experiment	Conceived and designed the experiments	Methodology	YES
5344870	28281272	MZ	2	helped to carry the experiment	helped to carry the experiment	Performed the experiments	Investigation	YES
5344870	28281272	WC	2	designed the whole experiment	designed the whole experiment	Conceived and designed the experiments	Methodology	YES
5344870	28281272	WG	2	helped to analyze the raw data	helped to analyze the raw data	Analyzed the data	Formal analysis	YES
5344870	28281272	XG	2	helpd on the paperwork	helpd on the paperwork	-	-	NO
4415921	25928076	ABCF	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415921	25928076	ABCF	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415921	25928076	ABCF	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415921	25928076	DBM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415921	25928076	DBM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415921	25928076	DBM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415921	25928076	JRRC	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415921	25928076	JRRC	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415921	25928076	LESN	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415921	25928076	LESN	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415921	25928076	LESN	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415921	25928076	OA	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415921	25928076	OA	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415921	25928076	OA	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415921	25928076	PPA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415921	25928076	PPA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415921	25928076	PPA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415921	25928076	PPA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415921	25928076	SM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415921	25928076	SM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415921	25928076	SM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415921	25928076	SM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415921	25928076	TCGM	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415921	25928076	TCGN	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4772849	26796577	CB	2	designed the experiments and wrote the manuscript	designed the experiments and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4772849	26796577	PC	2	designed the experiments and wrote the manuscript	designed the experiments and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4772849	26796577	PNC	2	designed the experiments and wrote the manuscript	designed the experiments and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4772849	26796577	SLB	2	designed the experiments and wrote the manuscript	designed the experiments and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
1939733	17710145	JF	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1939733	17710145	JF	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1939733	17710145	JF	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1939733	17710145	JF	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1939733	17710145	MF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1939733	17710145	MF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1939733	17710145	MF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5767297	29375604	All authors	2	listed have made a substantial, direct and intellectual contribution to the work, and approved it for publication	listed have made a substantial, direct and intellectual contribution to the work, and approved it for publication	-	-	NO
4415922	25928058	FL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4415922	25928058	HT	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415922	25928058	HT	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4415922	25928058	JZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415922	25928058	JZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415922	25928058	JZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415922	25928058	JZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415922	25928058	LZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415922	25928058	LZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415922	25928058	LZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415922	25928058	NW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4415922	25928058	RD	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4415922	25928058	XW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415922	25928058	XW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415922	25928058	XW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415922	25928058	YL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4415922	25928058	YW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4415922	25928058	YZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
3864147	24363626	Jung Eun Lee	2	have equally contributed to this study	have equally contributed to this study	-	-	NO
3864147	24363626	Yong Kyu Lee	2	have equally contributed to this study	have equally contributed to this study	-	-	NO
5346098	28284003	Both authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5346098	28284003	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
1939734	17710149	DH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1939734	17710149	DH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1939734	17710149	DH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1939734	17710149	DH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1939734	17710149	EG	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1939734	17710149	EG	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1939734	17710149	EG	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1939734	17710149	SB	PLoS5	Contributed reagents/materials/analysis tools|Edited the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1939734	17710149	SB	PLoS5	Contributed reagents/materials/analysis tools|Edited the paper	Edited the paper	Wrote the paper	Writing - Review & Editing	YES
1939734	17710149	SG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Edited the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1939734	17710149	SG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Edited the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1939734	17710149	SG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Edited the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1939734	17710149	SG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Edited the paper	Edited the paper	Wrote the paper	Writing - Review & Editing	YES
1939734	17710149	SS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1939734	17710149	SS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1939734	17710149	SS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5683332	29132313	AM	2	worked out and performed virulence tests and effective inoculation of plants for rna isolation	worked out and performed virulence tests and effective inoculation of plants for rna isolation	Performed the experiments	Investigation	YES
5683332	29132313	JP	2	is author of the conception of the study, its design, partial analysis of the data and their interpretation|commented by all authors	is author of the conception of the study, its design, partial analysis of the data and their interpretation	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
5683332	29132313	JP	2	is author of the conception of the study, its design, partial analysis of the data and their interpretation|commented by all authors	commented by all authors	-	-	NO
5683332	29132313	MK	2	designed and performed rna isolation and rna seq validation	designed and performed rna isolation and rna seq validation	Conceived and designed the experiments|Performed the experiments	Investigation|Validation	YES
5683332	29132313	WW	2	analysed data statistically	analysed data statistically	Analyzed the data	Formal analysis	YES
5299635	28194093	AF	2	designed the study, secured funding for project, assisted with data analysis and manuscript preparation	designed the study, secured funding for project, assisted with data analysis and manuscript preparation	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Funding acquisition|Methodology|Writing - Original Draft	YES
5299635	28194093	AK	2	provided medical oversight, subject screening, subject recruitment and assisted with data collection and manuscript preparation	provided medical oversight, subject screening, subject recruitment and assisted with data collection and manuscript preparation	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Resources|Supervision|Writing - Original Draft	YES
5299635	28194093	BR	2	carried out subject recruitment, data collection, coordination of the study and compliance	carried out subject recruitment, data collection, coordination of the study and compliance	Performed the experiments	Investigation|Project administration	YES
5299635	28194093	CK	2	assisted with data analysis and helped prepare the manuscript	assisted with data analysis and helped prepare the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5299635	28194093	HL	2	designed the study, secured funding for project, assisted with data analysis and manuscript preparation	designed the study, secured funding for project, assisted with data analysis and manuscript preparation	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Funding acquisition|Methodology|Writing - Original Draft	YES
5299635	28194093	JS	2	carried out subject recruitment, data collection, coordination of the study and compliance	carried out subject recruitment, data collection, coordination of the study and compliance	Performed the experiments	Investigation|Project administration	YES
5299635	28194093	SH	2	carried out subject recruitment, data collection, coordination of the study and compliance	carried out subject recruitment, data collection, coordination of the study and compliance	Performed the experiments	Investigation|Project administration	YES
5299635	28194093	TZ	2	designed the study, secured funding for project, assisted with data analysis and manuscript preparation	designed the study, secured funding for project, assisted with data analysis and manuscript preparation	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Funding acquisition|Methodology|Writing - Original Draft	YES
5767305	29375592	JW	1	Designing the work	Designing the work	Conceived and designed the experiments	-	YES
5767305	29375592	YH	1	Designing the work	Designing the work	Conceived and designed the experiments	-	YES
4415923	25928292	AC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415923	25928292	AC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415923	25928292	AC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415923	25928292	AC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415923	25928292	AH	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415923	25928292	AH	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415923	25928292	ES	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415923	25928292	ES	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415923	25928292	PW	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415923	25928292	RM	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5350083	28293868	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5350083	28293868	CS	2	conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5350083	28293868	DC	2	conceived the study|wrote the manuscript|constructed the recombinant strains	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5350083	28293868	DC	2	conceived the study|wrote the manuscript|constructed the recombinant strains	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5350083	28293868	DC	2	conceived the study|wrote the manuscript|constructed the recombinant strains	constructed the recombinant strains	Performed the experiments	Investigation	YES
5350083	28293868	EB	2	performed nmr structure determinations	performed nmr structure determinations	Performed the experiments	Investigation	YES
5350083	28293868	EC	2	constructed the recombinant strains|performed growth and purification experiments	constructed the recombinant strains	Performed the experiments	Investigation	YES
5350083	28293868	EC	2	constructed the recombinant strains|performed growth and purification experiments	performed growth and purification experiments	Performed the experiments	Investigation	YES
5350083	28293868	ID	2	performed growth and purification experiments	performed growth and purification experiments	Performed the experiments	Investigation	YES
5350083	28293868	Ottavia Argenzio	2	for helpful discussions on sec-tda analyses and shakeflask cultivations	for helpful discussions on sec-tda analyses and shakeflask cultivations	Analyzed the data	Formal analysis	YES
5350083	28293868	PD	2	performed sec-tda runs	performed sec-tda runs	Performed the experiments	Investigation	YES
5350083	28293868	Sabrina Reale	2	for helpful discussions on sec-tda analyses and shakeflask cultivations	for helpful discussions on sec-tda analyses and shakeflask cultivations	Analyzed the data	Formal analysis	YES
5350083	28293868	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
4801948	26702099	AIL-C	2	helped with experiments	helped with experiments	Performed the experiments	Investigation	YES
4801948	26702099	ARG	2	directed the work|wrote the manuscript	directed the work	-	Supervision	YES
4801948	26702099	ARG	2	directed the work|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4801948	26702099	BG	2	directed the work|wrote the manuscript	directed the work	-	Supervision	YES
4801948	26702099	BG	2	directed the work|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4801948	26702099	DFSC	2	analyzed the chip-seq data	analyzed the chip-seq data	Analyzed the data	Formal analysis	YES
4801948	26702099	HJP	2	performed experiments and analysis	performed experiments and analysis	Performed the experiments	Investigation	YES
4801948	26702099	JL	2	performed experiments and analysis	performed experiments and analysis	Performed the experiments	Investigation	YES
4801948	26702099	KK	2	helped with experiments	helped with experiments	Performed the experiments	Investigation	YES
4801948	26702099	RH	2	analyzed the chip-seq data	analyzed the chip-seq data	Analyzed the data	Formal analysis	YES
4801948	26702099	SB	2	analyzed the chip-seq data	analyzed the chip-seq data	Analyzed the data	Formal analysis	YES
4801948	26702099	VS	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5330006	28261001	AM	2	sample analysis	sample analysis	Analyzed the data	Formal analysis	YES
5330006	28261001	ASS	2	assisted in designing the study, writing the grant, study coordination, data collection, data analysis, and manuscript preparation	assisted in designing the study, writing the grant, study coordination, data collection, data analysis, and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Project administration|Writing - Original Draft	YES
5330006	28261001	DWS	2	assisted in research design and consultation	assisted in research design and consultation	Conceived and designed the experiments	-	YES
5330006	28261001	EK	2	assisted in research design and consultation	assisted in research design and consultation	Conceived and designed the experiments	-	YES
5330006	28261001	JT	2	assisted in date collection	assisted in date collection	-	-	NO
5330006	28261001	PB	2	assisted in date collection	assisted in date collection	-	-	NO
5683340	29132294	CP	PLoS52	conducted the experiments	conducted the experiments	Performed the experiments	Investigation	YES
5683340	29132294	EB	PLoS52	designed the study and wrote the manuscript|conducted the experiments|analyzed the data	designed the study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5683340	29132294	EB	PLoS52	designed the study and wrote the manuscript|conducted the experiments|analyzed the data	conducted the experiments	Performed the experiments	Investigation	YES
5683340	29132294	EB	PLoS52	designed the study and wrote the manuscript|conducted the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5683340	29132294	RP	PLoS52	conducted the experiments	conducted the experiments	Performed the experiments	Investigation	YES
5683340	29132294	SMR	PLoS52	designed the study and wrote the manuscript	designed the study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
1939735	17710138	AH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Data collection	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1939735	17710138	AH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Data collection	Analyzed the data	Analyzed the data	Formal analysis	YES
1939735	17710138	AH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Data collection	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1939735	17710138	AH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Data collection	Data collection	Performed the experiments	Investigation	YES
1939735	17710138	AL	PLoS5	Critical revision of the paper for important intellectual content|Data collection	Critical revision of the paper for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
1939735	17710138	AL	PLoS5	Critical revision of the paper for important intellectual content|Data collection	Data collection	Performed the experiments	Investigation	YES
1939735	17710138	CP	PLoS5	Critical revision of the paper for important intellectual content|Data collection	Critical revision of the paper for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
1939735	17710138	CP	PLoS5	Critical revision of the paper for important intellectual content|Data collection	Data collection	Performed the experiments	Investigation	YES
1939735	17710138	GK	PLoS5	Critical revision of the paper for important intellectual content|Data collection	Critical revision of the paper for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
1939735	17710138	GK	PLoS5	Critical revision of the paper for important intellectual content|Data collection	Data collection	Performed the experiments	Investigation	YES
1939735	17710138	HS	PLoS5	Conceived and designed the experiments|Interpretation of data|Critical revision of the paper for important intellectual content	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1939735	17710138	HS	PLoS5	Conceived and designed the experiments|Interpretation of data|Critical revision of the paper for important intellectual content	Interpretation of data	Analyzed the data	Formal analysis	YES
1939735	17710138	HS	PLoS5	Conceived and designed the experiments|Interpretation of data|Critical revision of the paper for important intellectual content	Critical revision of the paper for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
1939735	17710138	JG	PLoS5	Conceived and designed the experiments|Interpretation of data|Critical revision of the paper for important intellectual content|Data collection	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1939735	17710138	JG	PLoS5	Conceived and designed the experiments|Interpretation of data|Critical revision of the paper for important intellectual content|Data collection	Interpretation of data	Analyzed the data	Formal analysis	YES
1939735	17710138	JG	PLoS5	Conceived and designed the experiments|Interpretation of data|Critical revision of the paper for important intellectual content|Data collection	Critical revision of the paper for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
1939735	17710138	JG	PLoS5	Conceived and designed the experiments|Interpretation of data|Critical revision of the paper for important intellectual content|Data collection	Data collection	Performed the experiments	Investigation	YES
1939735	17710138	NL	PLoS5	Conceived and designed the experiments|Analyzed the data|Interpretation of data|Critical revision of the paper for important intellectual content	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1939735	17710138	NL	PLoS5	Conceived and designed the experiments|Analyzed the data|Interpretation of data|Critical revision of the paper for important intellectual content	Analyzed the data	Analyzed the data	Formal analysis	YES
1939735	17710138	NL	PLoS5	Conceived and designed the experiments|Analyzed the data|Interpretation of data|Critical revision of the paper for important intellectual content	Interpretation of data	Analyzed the data	Formal analysis	YES
1939735	17710138	NL	PLoS5	Conceived and designed the experiments|Analyzed the data|Interpretation of data|Critical revision of the paper for important intellectual content	Critical revision of the paper for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
1939735	17710138	NO	PLoS5	Conceived and designed the experiments|Interpretation of data|Critical revision of the paper for important intellectual content|Data collection	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1939735	17710138	NO	PLoS5	Conceived and designed the experiments|Interpretation of data|Critical revision of the paper for important intellectual content|Data collection	Interpretation of data	Analyzed the data	Formal analysis	YES
1939735	17710138	NO	PLoS5	Conceived and designed the experiments|Interpretation of data|Critical revision of the paper for important intellectual content|Data collection	Critical revision of the paper for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
1939735	17710138	NO	PLoS5	Conceived and designed the experiments|Interpretation of data|Critical revision of the paper for important intellectual content|Data collection	Data collection	Performed the experiments	Investigation	YES
5767312	29375595	AJ	2	conceived of and designed the experiments|collected plant material and performed rna extractions|performed gene ontology enrichment analysis, data interpretation and wrote the manuscript	conceived of and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5767312	29375595	AJ	2	conceived of and designed the experiments|collected plant material and performed rna extractions|performed gene ontology enrichment analysis, data interpretation and wrote the manuscript	collected plant material and performed rna extractions	Performed the experiments	Investigation	YES
5767312	29375595	AJ	2	conceived of and designed the experiments|collected plant material and performed rna extractions|performed gene ontology enrichment analysis, data interpretation and wrote the manuscript	performed gene ontology enrichment analysis, data interpretation and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5767312	29375595	All authors	2	discussed the results and commented on the manuscript	discussed the results and commented on the manuscript	-	-	NO
5767312	29375595	IS	2	conceived of and designed the experiments	conceived of and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5767312	29375595	JK	2	conceived of and designed the experiments	conceived of and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5767312	29375595	KG	2	run qpcr analysis of selected genes	run qpcr analysis of selected genes	Performed the experiments	Investigation	YES
5767312	29375595	MK	2	performed microarray data analysis	performed microarray data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5767312	29375595	MS	2	collected plant material and performed rna extractions|run qpcr analysis of selected genes	collected plant material and performed rna extractions	Performed the experiments	Investigation	YES
5767312	29375595	MS	2	collected plant material and performed rna extractions|run qpcr analysis of selected genes	run qpcr analysis of selected genes	Performed the experiments	Investigation	YES
4415924	25927702	ISG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415924	25927702	ISG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415924	25927702	ISG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415924	25927702	ISG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415924	25927702	MW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415924	25927702	MW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415924	25927702	MW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415924	25927702	NT	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415924	25927702	NY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415924	25927702	NY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415924	25927702	NY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415924	25927702	NY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415924	25927702	NY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415924	25927702	PG	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415924	25927702	RM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415924	25927702	RM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415924	25927702	RM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415924	25927702	XJS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5352697	28299749	AB	2	performed research	performed research	Performed the experiments	Investigation	YES
5352697	28299749	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5352697	28299749	HJH	2	designed research and wrote the paper|analyzed data	designed research and wrote the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5352697	28299749	HJH	2	designed research and wrote the paper|analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5352697	28299749	NH	2	designed research and wrote the paper|performed research|analyzed data	designed research and wrote the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5352697	28299749	NH	2	designed research and wrote the paper|performed research|analyzed data	performed research	Performed the experiments	Investigation	YES
5352697	28299749	NH	2	designed research and wrote the paper|performed research|analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
1939736	17710140	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1939736	17710140	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1939736	17710140	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1939736	17710140	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1939736	17710140	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5371271	28360825	All authors	2	contributed to the conception of the experimental design and drafting of the manuscript	contributed to the conception of the experimental design and drafting of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Writing - Original Draft	YES
5371271	28360825	JV	2	participated in data collection	participated in data collection	Performed the experiments	Investigation	YES
5371271	28360825	MF	2	participated in data collection	participated in data collection	Performed the experiments	Investigation	YES
5371271	28360825	NF	2	participated in data collection	participated in data collection	Performed the experiments	Investigation	YES
5683364	29132315	AA	2	conducted the qrt-pcr experiments with	conducted the qrt-pcr experiments with	Performed the experiments	Investigation	YES
5683364	29132315	All authors	2	reviewed the manuscript at every stage	reviewed the manuscript at every stage	Wrote the paper	Writing - Review & Editing	YES
5683364	29132315	KK	2	assisted with the experiments with	assisted with the experiments with	Performed the experiments	Investigation	YES
5683364	29132315	KUK	2	designed the study and conceptualised the methodology	designed the study and conceptualised the methodology	Conceived and designed the experiments|Performed the experiments	Conceptualization|Methodology	YES
5683364	29132315	Q-YS	2	revised the whole manuscript according to suggestions by referees, and supervised this study	revised the whole manuscript according to suggestions by referees, and supervised this study	Wrote the paper	Supervision|Writing - Review & Editing	YES
5683364	29132315	RU	2	conducted the qrt-pcr experiments with	conducted the qrt-pcr experiments with	Performed the experiments	Investigation	YES
5683364	29132315	X-LR	2	revised the whole manuscript according to suggestions by referees, and supervised this study	revised the whole manuscript according to suggestions by referees, and supervised this study	Wrote the paper	Supervision|Writing - Review & Editing	YES
5683364	29132315	ZN	2	designed the study and conceptualised the methodology	designed the study and conceptualised the methodology	Conceived and designed the experiments|Performed the experiments	Conceptualization|Methodology	YES
4801951	26903601	AGS	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
4801951	26903601	AS	2	supervised the study and wrote the paper	supervised the study and wrote the paper	Wrote the paper	Supervision|Writing - Original Draft	YES
4801951	26903601	EC	2	carried out, analyzed, and interpreted experiments	carried out, analyzed, and interpreted experiments	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4801951	26903601	GM	2	designed the study|carried out, analyzed, and interpreted experiments|supervised the study and wrote the paper	designed the study	Conceived and designed the experiments	Methodology	YES
4801951	26903601	GM	2	designed the study|carried out, analyzed, and interpreted experiments|supervised the study and wrote the paper	carried out, analyzed, and interpreted experiments	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4801951	26903601	GM	2	designed the study|carried out, analyzed, and interpreted experiments|supervised the study and wrote the paper	supervised the study and wrote the paper	Wrote the paper	Supervision|Writing - Original Draft	YES
4801951	26903601	MES	2	performed bnge assays, provided reagents and technical support	performed bnge assays, provided reagents and technical support	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4801951	26903601	RMB	2	carried out, analyzed, and interpreted experiments	carried out, analyzed, and interpreted experiments	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4415925	25928147	ML	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415925	25928147	ML	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415925	25928147	NC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415925	25928147	NC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415925	25928147	NC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415925	25928147	NC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415925	25928147	NC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415925	25928147	RQ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415925	25928147	RQ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415925	25928147	RQ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415925	25928147	RQ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415925	25928147	RQ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415925	25928147	YM	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415925	25928147	YM	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4620266	26543855	Ker-Kong Chen	2	the corresponding author contributed equally to this paper	the corresponding author contributed equally to this paper	-	-	NO
5352701	28299750	Both authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5352701	28299750	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5767313	29375605	AJ	2	conceptualized and designed the research and edited the manuscript	conceptualized and designed the research and edited the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
5767313	29375605	PC	2	conducted the experiments, analyzed the data, and edited the manuscript	conducted the experiments, analyzed the data, and edited the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
5767313	29375605	ZG	2	assisted in the experiments and writing of the manuscript	assisted in the experiments and writing of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4415926	25927608	AA	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415926	25927608	AMDG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415926	25927608	AMDG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415926	25927608	AMDG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415926	25927608	AMDG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415926	25927608	RT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415926	25927608	RT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415926	25927608	RT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415926	25927608	RT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415926	25927608	TV	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1939737	17710141	MB	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5683380	29132314	AJ	2	generated the proteomics data	generated the proteomics data	Performed the experiments	Investigation	YES
5683380	29132314	AJC	2	contributed to the construction of the sample-specific databases|provided significant editorial revisions	contributed to the construction of the sample-specific databases	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources|Software	YES
5683380	29132314	AJC	2	contributed to the construction of the sample-specific databases|provided significant editorial revisions	provided significant editorial revisions	Wrote the paper	Writing - Review & Editing	YES
5683380	29132314	JG	2	generated the rna seq data|contributed to the construction of the sample-specific databases	generated the rna seq data	Performed the experiments	Investigation	YES
5683380	29132314	JG	2	generated the rna seq data|contributed to the construction of the sample-specific databases	contributed to the construction of the sample-specific databases	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources|Software	YES
5683380	29132314	JMP	2	conceived the study|analyzed the mass spectrometry data and conducted the comparative analyses	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5683380	29132314	JMP	2	conceived the study|analyzed the mass spectrometry data and conducted the comparative analyses	analyzed the mass spectrometry data and conducted the comparative analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5683380	29132314	KK	2	conceived the study|oversaw the selection and sampling of the vervet liver biopies	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5683380	29132314	KK	2	conceived the study|oversaw the selection and sampling of the vervet liver biopies	oversaw the selection and sampling of the vervet liver biopies	Performed the experiments	Investigation|Supervision	YES
5683380	29132314	LAC	2	conceived the study|generated the rna seq data|provided significant editorial revisions	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5683380	29132314	LAC	2	conceived the study|generated the rna seq data|provided significant editorial revisions	generated the rna seq data	Performed the experiments	Investigation	YES
5683380	29132314	LAC	2	conceived the study|generated the rna seq data|provided significant editorial revisions	provided significant editorial revisions	Wrote the paper	Writing - Review & Editing	YES
5683380	29132314	LMS	2	contributed to the construction of the sample-specific databases|provided significant editorial revisions	contributed to the construction of the sample-specific databases	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources|Software	YES
5683380	29132314	LMS	2	contributed to the construction of the sample-specific databases|provided significant editorial revisions	provided significant editorial revisions	Wrote the paper	Writing - Review & Editing	YES
5683380	29132314	MO	2	conceived the study|generated the proteomics data	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5683380	29132314	MO	2	conceived the study|generated the proteomics data	generated the proteomics data	Performed the experiments	Investigation	YES
5683380	29132314	MRS	2	contributed to the construction of the sample-specific databases	contributed to the construction of the sample-specific databases	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources|Software	YES
5355397	28303550	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5355397	28303550	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5355397	28303550	YSK	2	wrote this manuscript	wrote this manuscript	Wrote the paper	Writing - Original Draft	YES
4801952	26903600	All authors	2	designed experiments and interpreted data	designed experiments and interpreted data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
4801952	26903600	DAC	2	performed experiments during the revision of the manuscript	performed experiments during the revision of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4801952	26903600	EK	2	generated and analyzed sororin conditional knockout mice and sororin-lap-aid cells	generated and analyzed sororin conditional knockout mice and sororin-lap-aid cells	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4801952	26903600	GAB	2	generated and analyzed smc3 conditional knockout fibroblasts	generated and analyzed smc3 conditional knockout fibroblasts	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4801952	26903600	GW	2	performed experiments during the revision of the manuscript	performed experiments during the revision of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4801952	26903600	HE	2	performed peak calling and correlation analysis	performed peak calling and correlation analysis	Performed the experiments	Investigation	YES
4801952	26903600	J-MP	2	prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
4801952	26903600	MHI-A	2	analyzed mouse embryonic development	analyzed mouse embryonic development	Analyzed the data	Formal analysis	YES
4801952	26903600	MPI	2	performed chip and dip experiments	performed chip and dip experiments	Performed the experiments	Investigation	YES
4801952	26903600	RL	2	performed photobleaching and rnai experiments and analyzed cells overexpressing sororin|prepared the manuscript	performed photobleaching and rnai experiments and analyzed cells overexpressing sororin	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4801952	26903600	RL	2	performed photobleaching and rnai experiments and analyzed cells overexpressing sororin|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5767322	29375610	AF	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5767322	29375610	AP	PLoS52	conceived developed and coordinated the research|analyzed the data	conceived developed and coordinated the research	Conceived and designed the experiments	Conceptualization|Project administration	YES
5767322	29375610	AP	PLoS52	conceived developed and coordinated the research|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5767322	29375610	All authors	PLoS52	read and approved the final version of the manuscript	read and approved the final version of the manuscript	-	-	NO
5767322	29375610	GM	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5767322	29375610	RG	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5767322	29375610	SA	PLoS52	analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5767322	29375610	SA	PLoS52	analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415927	25927612	GPK	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415927	25927612	HGW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415927	25927612	HGW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415927	25927612	KT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415927	25927612	KT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415927	25927612	KT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415927	25927612	KT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415927	25927612	KT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415927	25927612	MPP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415927	25927612	MPP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415927	25927612	MPP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415927	25927612	MPP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415927	25927612	SEB	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4415927	25927612	SEB	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5767325	29375613	IO	2	conceived this review and wrote the manuscript	conceived this review and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
5767325	29375613	MS	2	conceived this review and wrote the manuscript	conceived this review and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
1939874	17710133	AW	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1939874	17710133	AW	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1939874	17710133	BS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1939874	17710133	HA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1939874	17710133	HA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1939874	17710133	HA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1939874	17710133	KF	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1939874	17710133	NT	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1939874	17710133	NT	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1939874	17710133	SE	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1939874	17710133	SE	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5397733	28428736	DF	2	carried out the elisa measurments	carried out the elisa measurments	Performed the experiments	Investigation	YES
5397733	28428736	JA	2	participated in design and helped to draft the manuscript	participated in design and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
5397733	28428736	MT	2	design and control the diet, participated in the hepcidin measurment, drafted the manuscript	design and control the diet, participated in the hepcidin measurment, drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
5397733	28428736	RC	2	participated in design and helped to draft the manuscript	participated in design and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
5397733	28428736	WS	2	participated in the designe of the study and helped to draft the manuscript	participated in the designe of the study and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5355400	28303551	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5355400	28303551	GYY	2	carried out the experimental studies, participated in the experiments and drafted the manuscript	carried out the experimental studies, participated in the experiments and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5355400	28303551	MHY	2	conceived of the study, and participated in its design and coordination and helped to draft the manuscript	conceived of the study, and participated in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
5355400	28303551	PC	2	conceived of the study, and participated in its design and coordination and helped to draft the manuscript	conceived of the study, and participated in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
5355400	28303551	SSZ	2	carried out the experimental studies, participated in the experiments and drafted the manuscript	carried out the experimental studies, participated in the experiments and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5355400	28303551	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5355400	28303551	WJK	2	participated in the design of the study and performed the statistical analysis	participated in the design of the study and performed the statistical analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5355400	28303551	WYG	2	participated in the design of the study and performed the statistical analysis	participated in the design of the study and performed the statistical analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5355400	28303551	XRW	2	conceived of the study, and participated in its design and coordination and helped to draft the manuscript	conceived of the study, and participated in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
5355400	28303551	YLH	2	carried out the analysis	carried out the analysis	Performed the experiments	Investigation	YES
5683454	29132309	EG	2	analyzed the data and wrote the paper	analyzed the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5683454	29132309	OM	2	analyzed the data and wrote the paper	analyzed the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5683454	29132309	TT	2	analyzed the data and wrote the paper	analyzed the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4415928	25927362	AYW	PLoS5	Contributed reagents/materials/analysis tools|Read and approved this final manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415928	25927362	AYW	PLoS5	Contributed reagents/materials/analysis tools|Read and approved this final manuscript	Read and approved this final manuscript	Wrote the paper	Writing - Review & Editing	YES
4415928	25927362	JSR	PLoS5	Performed the experiments|Read and approved this final manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4415928	25927362	JSR	PLoS5	Performed the experiments|Read and approved this final manuscript	Read and approved this final manuscript	Wrote the paper	Writing - Review & Editing	YES
4415928	25927362	LHS	PLoS5	Contributed reagents/materials/analysis tools|Read and approved this final manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415928	25927362	LHS	PLoS5	Contributed reagents/materials/analysis tools|Read and approved this final manuscript	Read and approved this final manuscript	Wrote the paper	Writing - Review & Editing	YES
4415928	25927362	LT	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Read and approved this final manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4415928	25927362	LT	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Read and approved this final manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4415928	25927362	LT	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Read and approved this final manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415928	25927362	LT	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Read and approved this final manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415928	25927362	LT	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Read and approved this final manuscript	Read and approved this final manuscript	Wrote the paper	Writing - Review & Editing	YES
4415928	25927362	PTZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Read and approved this final manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415928	25927362	PTZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Read and approved this final manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4415928	25927362	PTZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Read and approved this final manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4415928	25927362	PTZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Read and approved this final manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415928	25927362	PTZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Read and approved this final manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415928	25927362	PTZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Read and approved this final manuscript	Read and approved this final manuscript	Wrote the paper	Writing - Review & Editing	YES
4415928	25927362	SLW	PLoS5	Contributed reagents/materials/analysis tools|Read and approved this final manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415928	25927362	SLW	PLoS5	Contributed reagents/materials/analysis tools|Read and approved this final manuscript	Read and approved this final manuscript	Wrote the paper	Writing - Review & Editing	YES
4415928	25927362	WXC	PLoS5	Contributed reagents/materials/analysis tools|Read and approved this final manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415928	25927362	WXC	PLoS5	Contributed reagents/materials/analysis tools|Read and approved this final manuscript	Read and approved this final manuscript	Wrote the paper	Writing - Review & Editing	YES
4415928	25927362	XBS	PLoS5	Contributed reagents/materials/analysis tools|Read and approved this final manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415928	25927362	XBS	PLoS5	Contributed reagents/materials/analysis tools|Read and approved this final manuscript	Read and approved this final manuscript	Wrote the paper	Writing - Review & Editing	YES
4415928	25927362	YL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Read and approved this final manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415928	25927362	YL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Read and approved this final manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4415928	25927362	YL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Read and approved this final manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415928	25927362	YL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Read and approved this final manuscript	Read and approved this final manuscript	Wrote the paper	Writing - Review & Editing	YES
4415928	25927362	YLS	PLoS5	Contributed reagents/materials/analysis tools|Read and approved this final manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415928	25927362	YLS	PLoS5	Contributed reagents/materials/analysis tools|Read and approved this final manuscript	Read and approved this final manuscript	Wrote the paper	Writing - Review & Editing	YES
4415928	25927362	YPL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Read and approved this final manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415928	25927362	YPL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Read and approved this final manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4415928	25927362	YPL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Read and approved this final manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4415928	25927362	YPL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Read and approved this final manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415928	25927362	YPL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Read and approved this final manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415928	25927362	YPL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Read and approved this final manuscript	Read and approved this final manuscript	Wrote the paper	Writing - Review & Editing	YES
4415928	25927362	YYW	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Read and approved this final manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4415928	25927362	YYW	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Read and approved this final manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415928	25927362	YYW	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Read and approved this final manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415928	25927362	YYW	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Read and approved this final manuscript	Read and approved this final manuscript	Wrote the paper	Writing - Review & Editing	YES
4415928	25927362	YZC	PLoS5	Contributed reagents/materials/analysis tools|Read and approved this final manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415928	25927362	YZC	PLoS5	Contributed reagents/materials/analysis tools|Read and approved this final manuscript	Read and approved this final manuscript	Wrote the paper	Writing - Review & Editing	YES
4415928	25927362	ZGL	PLoS5	Wrote the paper|Read and approved this final manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415928	25927362	ZGL	PLoS5	Wrote the paper|Read and approved this final manuscript	Read and approved this final manuscript	Wrote the paper	Writing - Review & Editing	YES
4415928	25927362	ZHW	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Read and approved this final manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4415928	25927362	ZHW	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Read and approved this final manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415928	25927362	ZHW	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Read and approved this final manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415928	25927362	ZHW	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Read and approved this final manuscript	Read and approved this final manuscript	Wrote the paper	Writing - Review & Editing	YES
4415928	25927362	ZJZ	PLoS5	Contributed reagents/materials/analysis tools|Read and approved this final manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415928	25927362	ZJZ	PLoS5	Contributed reagents/materials/analysis tools|Read and approved this final manuscript	Read and approved this final manuscript	Wrote the paper	Writing - Review & Editing	YES
4818766	26848154	AM	2	characterized the effects of rapamycin on mitochondrial function	characterized the effects of rapamycin on mitochondrial function	Performed the experiments	Investigation	YES
4818766	26848154	All authors	2	critically read and commented on the manuscript	critically read and commented on the manuscript	-	-	NO
4818766	26848154	BMC	2	conducted transfections with mutated rhebn153t and western blots in liver tissues	conducted transfections with mutated rhebn153t and western blots in liver tissues	Performed the experiments	Investigation	YES
4818766	26848154	CCM	2	did majority of the experiments and contributed to the experimental design and writing of the manuscript	did majority of the experiments and contributed to the experimental design and writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
4818766	26848154	DJ	2	conducted real time pcr	conducted real time pcr	Performed the experiments	Investigation	YES
4818766	26848154	DM	2	contributed to the experimental design	contributed to the experimental design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4818766	26848154	DRG	2	performed 3d electron microscopy	performed 3d electron microscopy	Performed the experiments	Investigation	YES
4818766	26848154	E.M.	2	in human fibroblasts	in human fibroblasts	-	-	NO
4818766	26848154	GN	2	provided technical expertise in microscopy and lentiviral transfection experiments	provided technical expertise in microscopy and lentiviral transfection experiments	Performed the experiments	Investigation	YES
4818766	26848154	GQ	2	performed 3d electron microscopy	performed 3d electron microscopy	Performed the experiments	Investigation	YES
4818766	26848154	GS	2	conducted trap assays	conducted trap assays	Performed the experiments	Investigation	YES
4818766	26848154	JB	2	conducted elisas	conducted elisas	Performed the experiments	Investigation	YES
4818766	26848154	JC	2	performed rna seq analysis	performed rna seq analysis	Performed the experiments	Investigation	YES
4818766	26848154	JFP	2	designed and supervised the study and wrote the manuscript	designed and supervised the study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Original Draft	YES
4818766	26848154	LG	2	performed mtdna copy number assay in human cells	performed mtdna copy number assay in human cells	Performed the experiments	Investigation	YES
4818766	26848154	MC	2	performed t	performed t	Performed the experiments	Investigation	YES
4818766	26848154	MDR	2	conducted real time pcr	conducted real time pcr	Performed the experiments	Investigation	YES
4818766	26848154	PDA	2	performed rna seq analysis|conducted oncogene-induced senescence experiments	performed rna seq analysis	Performed the experiments	Investigation	YES
4818766	26848154	PDA	2	performed rna seq analysis|conducted oncogene-induced senescence experiments	conducted oncogene-induced senescence experiments	Performed the experiments	Investigation	YES
4818766	26848154	RA	2	performed if, mtdna copy number and sen-b-gal activity assays	performed if, mtdna copy number and sen-b-gal activity assays	Performed the experiments	Investigation	YES
4818766	26848154	RC	2	conducted trap assays	conducted trap assays	Performed the experiments	Investigation	YES
4818766	26848154	RH	2	conducted oncogene-induced senescence experiments	conducted oncogene-induced senescence experiments	Performed the experiments	Investigation	YES
4818766	26848154	SM	2	characterized the effects of rapamycin on mitochondrial function	characterized the effects of rapamycin on mitochondrial function	Performed the experiments	Investigation	YES
4818766	26848154	SWGT	2	provided the plasmids and technical support for the yfp-parkin experiments	provided the plasmids and technical support for the yfp-parkin experiments	Performed the experiments	Investigation	YES
4818766	26848154	TvZ	2	contributed to the experimental design	contributed to the experimental design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4818766	26848154	VIK	2	conducted transfections with mutated rhebn153t and western blots in liver tissues	conducted transfections with mutated rhebn153t and western blots in liver tissues	Performed the experiments	Investigation	YES
5401469	28439212	All authors	2	confirmed the current manuscript	confirmed the current manuscript	-	-	NO
5401469	28439212	MK	2	participated in whole steps, including animal care, training and molecular tests and draft the manuscript	participated in whole steps, including animal care, training and molecular tests and draft the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5401469	28439212	MRD	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5401469	28439212	PK	2	performed the coordination and helped to biochemical and immunoblotting studies	performed the coordination and helped to biochemical and immunoblotting studies	Performed the experiments	Investigation|Project administration	YES
5401469	28439212	PM	2	participated in the plan of the study	participated in the plan of the study	-	-	NO
5401469	28439212	SDN	2	participated in the statistical analyzing	participated in the statistical analyzing	Analyzed the data	Formal analysis	YES
5359262	28321795	All authors	2	have read and approved the final manuscript	have read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5359262	28321795	JM	2	participated in the design of the study, supervised the research work and reviewed the manuscript	participated in the design of the study, supervised the research work and reviewed the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Supervision|Writing - Review & Editing	YES
5359262	28321795	PS	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5359262	28321795	SD	2	supervised the research work, administered the project and funding	supervised the research work, administered the project and funding	Performed the experiments	Funding acquisition|Investigation|Project administration|Supervision	YES
5359262	28321795	VR	2	designed the statistical optimization studies, drafted and edited the original manuscript	designed the statistical optimization studies, drafted and edited the original manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5683460	29132316	CTL	2	designed experiments and interpreted the results	designed experiments and interpreted the results	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5683460	29132316	CYC	2	helped to collect and analyze the data	helped to collect and analyze the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5683460	29132316	HXZ	2	helped to collect and analyze the data	helped to collect and analyze the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5683460	29132316	LFG	2	conceived this project|designed experiments and interpreted the results	conceived this project	Conceived and designed the experiments	Conceptualization	YES
5683460	29132316	LFG	2	conceived this project|designed experiments and interpreted the results	designed experiments and interpreted the results	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5683460	29132316	MQX	2	helped to collect and analyze the data	helped to collect and analyze the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5683460	29132316	QW	2	helped to collect and analyze the data	helped to collect and analyze the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5683460	29132316	QZ	2	conceived this project|designed experiments and interpreted the results|wrote the manuscript	conceived this project	Conceived and designed the experiments	Conceptualization	YES
5683460	29132316	QZ	2	conceived this project|designed experiments and interpreted the results|wrote the manuscript	designed experiments and interpreted the results	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5683460	29132316	QZ	2	conceived this project|designed experiments and interpreted the results|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5683460	29132316	YBG	2	helped to collect and analyze the data	helped to collect and analyze the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5767604	29375596	All authors	2	have read, revised, and approved the final manuscript	have read, revised, and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5767604	29375596	EVD	2	outlined and designed the study|conceived and supervised the experiments and critically revised the manuscript	outlined and designed the study	Conceived and designed the experiments	Methodology	YES
5767604	29375596	EVD	2	outlined and designed the study|conceived and supervised the experiments and critically revised the manuscript	conceived and supervised the experiments and critically revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Supervision|Writing - Review & Editing	YES
5767604	29375596	LE	2	outlined and designed the study|performed the experiments, analyzed and interpreted the data and prepared the manuscript	outlined and designed the study	Conceived and designed the experiments	Methodology	YES
5767604	29375596	LE	2	outlined and designed the study|performed the experiments, analyzed and interpreted the data and prepared the manuscript	performed the experiments, analyzed and interpreted the data and prepared the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
1939875	17710134	CR	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1939875	17710134	CR	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1939875	17710134	GT	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1939875	17710134	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1939875	17710134	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1939875	17710134	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1939875	17710134	JC	PLoS5	Provided parasitological expertise in parasite collection and identification	Provided parasitological expertise in parasite collection and identification	Performed the experiments	Investigation	YES
1939875	17710134	LB	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415929	25927706	AL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415929	25927706	AL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415929	25927706	AL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415929	25927706	AL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415929	25927706	AL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415929	25927706	JM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415929	25927706	JM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415929	25927706	JM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415929	25927706	JM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415929	25927706	MJG	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415929	25927706	MJG	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415929	25927706	MZ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415929	25927706	MZ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415929	25927706	MZ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415929	25927706	MZ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415929	25927706	PK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415929	25927706	PK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415929	25927706	PK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5408473	28465675	CS	2	contributed to this review	contributed to this review	-	-	NO
5408473	28465675	SH	2	contributed to this review	contributed to this review	-	-	NO
5408473	28465675	SS	2	contributed to this review	contributed to this review	-	-	NO
5408473	28465675	YM	2	contributed to this review	contributed to this review	-	-	NO
4855687	26903602	AF	PLoS52	performed the experiments|developed protocols and provided reagents	performed the experiments	Performed the experiments	Investigation	YES
4855687	26903602	AF	PLoS52	performed the experiments|developed protocols and provided reagents	developed protocols and provided reagents	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Methodology|Resources	YES
4855687	26903602	APJ	PLoS52	analysed data|planned the project/supervised experiments|wrote the manuscript	analysed data	Analyzed the data	Formal analysis	YES
4855687	26903602	APJ	PLoS52	analysed data|planned the project/supervised experiments|wrote the manuscript	planned the project/supervised experiments	Conceived and designed the experiments	Conceptualization|Supervision	YES
4855687	26903602	APJ	PLoS52	analysed data|planned the project/supervised experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4855687	26903602	AR	PLoS52	developed protocols and provided reagents	developed protocols and provided reagents	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Methodology|Resources	YES
4855687	26903602	BR	PLoS52	performed the experiments|analysed data	performed the experiments	Performed the experiments	Investigation	YES
4855687	26903602	BR	PLoS52	performed the experiments|analysed data	analysed data	Analyzed the data	Formal analysis	YES
4855687	26903602	EA	PLoS52	analysed data	analysed data	Analyzed the data	Formal analysis	YES
4855687	26903602	FD	PLoS52	developed protocols and provided reagents	developed protocols and provided reagents	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Methodology|Resources	YES
4855687	26903602	FK	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
4855687	26903602	GG	PLoS52	analysed data	analysed data	Analyzed the data	Formal analysis	YES
4855687	26903602	KJM	PLoS52	performed the experiments|analysed data|planned the project/supervised experiments|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
4855687	26903602	KJM	PLoS52	performed the experiments|analysed data|planned the project/supervised experiments|wrote the manuscript	analysed data	Analyzed the data	Formal analysis	YES
4855687	26903602	KJM	PLoS52	performed the experiments|analysed data|planned the project/supervised experiments|wrote the manuscript	planned the project/supervised experiments	Conceived and designed the experiments	Conceptualization|Supervision	YES
4855687	26903602	KJM	PLoS52	performed the experiments|analysed data|planned the project/supervised experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4855687	26903602	KR	PLoS52	planned the project/supervised experiments	planned the project/supervised experiments	Conceived and designed the experiments	Conceptualization|Supervision	YES
4855687	26903602	LL	PLoS52	performed the experiments|analysed data	performed the experiments	Performed the experiments	Investigation	YES
4855687	26903602	LL	PLoS52	performed the experiments|analysed data	analysed data	Analyzed the data	Formal analysis	YES
4855687	26903602	MAMR	PLoS52	performed the experiments|analysed data|planned the project/supervised experiments|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
4855687	26903602	MAMR	PLoS52	performed the experiments|analysed data|planned the project/supervised experiments|wrote the manuscript	analysed data	Analyzed the data	Formal analysis	YES
4855687	26903602	MAMR	PLoS52	performed the experiments|analysed data|planned the project/supervised experiments|wrote the manuscript	planned the project/supervised experiments	Conceived and designed the experiments	Conceptualization|Supervision	YES
4855687	26903602	MAMR	PLoS52	performed the experiments|analysed data|planned the project/supervised experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4855687	26903602	PC	PLoS52	performed the experiments|analysed data	performed the experiments	Performed the experiments	Investigation	YES
4855687	26903602	PC	PLoS52	performed the experiments|analysed data	analysed data	Analyzed the data	Formal analysis	YES
4855687	26903602	PSD	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
4855687	26903602	RER	PLoS52	performed the experiments|analysed data|planned the project/supervised experiments	performed the experiments	Performed the experiments	Investigation	YES
4855687	26903602	RER	PLoS52	performed the experiments|analysed data|planned the project/supervised experiments	analysed data	Analyzed the data	Formal analysis	YES
4855687	26903602	RER	PLoS52	performed the experiments|analysed data|planned the project/supervised experiments	planned the project/supervised experiments	Conceived and designed the experiments	Conceptualization|Supervision	YES
4855687	26903602	ZT	PLoS52	performed the experiments|analysed data	performed the experiments	Performed the experiments	Investigation	YES
4855687	26903602	ZT	PLoS52	performed the experiments|analysed data	analysed data	Analyzed the data	Formal analysis	YES
1939876	17710146	AK	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1939876	17710146	AK	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1939876	17710146	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1939876	17710146	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1939876	17710146	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1939876	17710146	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1939876	17710146	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1939876	17710146	MM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1939876	17710146	MS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1939876	17710146	YC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1939876	17710146	YC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1939876	17710146	YC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1939876	17710146	YC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1939876	17710146	YC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5683534	29132308	HS	2	collected samples and phenotypes	collected samples and phenotypes	Performed the experiments	Investigation	YES
5683534	29132308	MT	2	performed dna extraction, identified the polymorphisms, and performed genotyping	performed dna extraction, identified the polymorphisms, and performed genotyping	Performed the experiments	Investigation	YES
5683534	29132308	NS	2	performed dna extraction, identified the polymorphisms, and performed genotyping	performed dna extraction, identified the polymorphisms, and performed genotyping	Performed the experiments	Investigation	YES
5683534	29132308	SS	2	conceived and designed the experiments, performed functional experiments, and contributed to writing and improving the manuscript	conceived and designed the experiments, performed functional experiments, and contributed to writing and improving the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5683534	29132308	TA	2	performed dna extraction, identified the polymorphisms, and performed genotyping	performed dna extraction, identified the polymorphisms, and performed genotyping	Performed the experiments	Investigation	YES
5683534	29132308	TK	2	designed the experiment and managed the entire project	designed the experiment and managed the entire project	Conceived and designed the experiments	Methodology|Project administration	YES
5683534	29132308	TO	2	performed dna extraction, identified the polymorphisms, and performed genotyping	performed dna extraction, identified the polymorphisms, and performed genotyping	Performed the experiments	Investigation	YES
5683534	29132308	YU	2	conceived and designed the experiments, performed the statistical and bioinformatics analyses, and contributed to writing and improving the manuscript	conceived and designed the experiments, performed the statistical and bioinformatics analyses, and contributed to writing and improving the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5360742	28324616	AS	PLoS52	conceived and designed the experiments|made a substantial contribution to the analysis and interpretation of the data presented	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5360742	28324616	AS	PLoS52	conceived and designed the experiments|made a substantial contribution to the analysis and interpretation of the data presented	made a substantial contribution to the analysis and interpretation of the data presented	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5360742	28324616	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5360742	28324616	MHE	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5360742	28324616	MTG	PLoS52	made a substantial contribution to the analysis and interpretation of the data presented	made a substantial contribution to the analysis and interpretation of the data presented	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5360742	28324616	ZB	PLoS52	performed the experiments|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5360742	28324616	ZB	PLoS52	performed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415930	25928294	AGJ	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415930	25928294	AGJ	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415930	25928294	DT	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4415930	25928294	JPT	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4415930	25928294	JPT	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415930	25928294	KI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415930	25928294	KI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415930	25928294	KI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415930	25928294	KI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415930	25928294	RA	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415930	25928294	SBN	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5767606	29375591	CH-V	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5767606	29375591	JC	PLoS52	wrote the paper|prepared figures	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5767606	29375591	JC	PLoS52	wrote the paper|prepared figures	prepared figures	-	Visualization	YES
5767606	29375591	SB	PLoS52	wrote the paper|prepared figures	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5767606	29375591	SB	PLoS52	wrote the paper|prepared figures	prepared figures	-	Visualization	YES
5437483	28529463	CK	4	analyzed and interpreted by	analyzed and interpreted by	Analyzed the data	Formal analysis	YES
5437483	28529463	CW	4	The study was designed by|analyzed and interpreted by|manuscript preparation was undertaken by	The study was designed by	Conceived and designed the experiments	Methodology	YES
5437483	28529463	CW	4	The study was designed by|analyzed and interpreted by|manuscript preparation was undertaken by	analyzed and interpreted by	Analyzed the data	Formal analysis	YES
5437483	28529463	CW	4	The study was designed by|analyzed and interpreted by|manuscript preparation was undertaken by	manuscript preparation was undertaken by	Wrote the paper	Writing - Original Draft	YES
5437483	28529463	EA	4	The study was designed by|analyzed and interpreted by|manuscript preparation was undertaken by	The study was designed by	Conceived and designed the experiments	Methodology	YES
5437483	28529463	EA	4	The study was designed by|analyzed and interpreted by|manuscript preparation was undertaken by	analyzed and interpreted by	Analyzed the data	Formal analysis	YES
5437483	28529463	EA	4	The study was designed by|analyzed and interpreted by|manuscript preparation was undertaken by	manuscript preparation was undertaken by	Wrote the paper	Writing - Original Draft	YES
4864278	27154206	DE	2	designed and carried out experiments, analysed the data and co-wrote the manuscript	designed and carried out experiments, analysed the data and co-wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4864278	27154206	KR	2	conceived the project, analysed the data and wrote the manuscript	conceived the project, analysed the data and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
4864278	27154206	MALLS	2	analysed and discussed the data	analysed and discussed the data	Analyzed the data	Formal analysis	YES
4864278	27154206	MGK	2	designed and carried out experiments, analysed the data and co-wrote the manuscript	designed and carried out experiments, analysed the data and co-wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
1939877	17710147	AP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1939877	17710147	DS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1939877	17710147	JH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1939877	17710147	JH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1939877	17710147	JH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1939877	17710147	JS	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1939877	17710147	JS	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1939877	17710147	KS	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1939877	17710147	KS	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1939877	17710147	LF	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1939877	17710147	MV	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1939877	17710147	MW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1939877	17710147	MW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1939877	17710147	MW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1939877	17710147	MW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1939877	17710147	RH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1939877	17710147	WB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1939877	17710147	WB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1939877	17710147	WB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5767732	29367856	BL	2	helped in plant culture and hairy root induction experiments	helped in plant culture and hairy root induction experiments	Performed the experiments	Investigation	YES
5767732	29367856	HS	2	helped in qrt-pcr experiments	helped in qrt-pcr experiments	Performed the experiments	Investigation	YES
5767732	29367856	JY	2	designed the entire experiment, performed organic acid examination by enzymatic assay, and wrote the manuscript	designed the entire experiment, performed organic acid examination by enzymatic assay, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5767732	29367856	WS	2	helped in plant culture and hairy root induction experiments	helped in plant culture and hairy root induction experiments	Performed the experiments	Investigation	YES
5767732	29367856	YX	2	performed the subcellular localization experiments	performed the subcellular localization experiments	Performed the experiments	Investigation	YES
5767732	29367856	YZ	2	performed most of the experiments|helped to design the experiments and performed organic acid measurement by hplc	performed most of the experiments	Performed the experiments	Investigation	YES
5767732	29367856	YZ	2	performed most of the experiments|helped to design the experiments and performed organic acid measurement by hplc	helped to design the experiments and performed organic acid measurement by hplc	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5767732	29367856	ZS	2	helped in qrt-pcr experiments	helped in qrt-pcr experiments	Performed the experiments	Investigation	YES
5360750	28324615	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5360750	28324615	IFC	2	conceived of the study, participated in its design and coordination, interpreted the data, and drafted the manuscript	conceived of the study, participated in its design and coordination, interpreted the data, and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Project administration|Writing - Original Draft	YES
5360750	28324615	KJFM	2	performed the experiments and the data analysis	performed the experiments and the data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5360750	28324615	LAM	2	performed the experiments and the data analysis	performed the experiments and the data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5360750	28324615	MC	2	participated in its design and coordination, interpreted the data, and helped to draft the manuscript	participated in its design and coordination, interpreted the data, and helped to draft the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Project administration|Writing - Original Draft	YES
5360750	28324615	RAC	2	participated in the design and coordination of the study, performed the experiments, interpreted the data, and drafted the manuscript	participated in the design and coordination of the study, performed the experiments, interpreted the data, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Project administration|Writing - Original Draft	YES
5360750	28324615	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
4415931	25927917	AF	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415931	25927917	AF	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415931	25927917	AF	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415931	25927917	CA	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415931	25927917	CA	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415931	25927917	DD	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415931	25927917	DD	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415931	25927917	DD	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415931	25927917	DD	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415931	25927917	EG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415931	25927917	EG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415931	25927917	EG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415931	25927917	EG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415931	25927917	FL	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415931	25927917	FL	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415931	25927917	JL	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415931	25927917	MD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415931	25927917	MD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415931	25927917	MD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415931	25927917	MD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415931	25927917	MD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5683544	29132310	HLP	2	attended the data analyses and discussion	attended the data analyses and discussion	Analyzed the data	Formal analysis	YES
5683544	29132310	HSN	2	attended the data analyses and discussion	attended the data analyses and discussion	Analyzed the data	Formal analysis	YES
5683544	29132310	JPH	2	designed the experiments, provided research platform, guided the research and revised the manuscript	designed the experiments, provided research platform, guided the research and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Review & Editing	YES
5683544	29132310	LDZ	2	attended the data analyses and discussion	attended the data analyses and discussion	Analyzed the data	Formal analysis	YES
5683544	29132310	SSL	2	attended the data analyses and discussion	attended the data analyses and discussion	Analyzed the data	Formal analysis	YES
5683544	29132310	YMW	2	maintained the experimental platform and participated in the bench work	maintained the experimental platform and participated in the bench work	Performed the experiments	Investigation	YES
5683544	29132310	ZWC	2	assembled the mitochondrial genome, annotated the mitochondrial genomes, performed the data analysis and prepared the manuscript	assembled the mitochondrial genome, annotated the mitochondrial genomes, performed the data analysis and prepared the manuscript	Analyzed the data|Wrote the paper	Data curation|Formal analysis|Writing - Original Draft	YES
3865736	24363620	Humayoon Shafiq Satti	2	contributed equally to this work	contributed equally to this work	-	-	NO
3865736	24363620	Sabir Hussain	2	contributed equally to this work	contributed equally to this work	-	-	NO
5452353	28572749	EC	2	with the	with the	-	-	NO
5452353	28572749	MB	2	assisted ec with the	assisted ec with the	-	-	NO
5452353	28572749	SS	2	assisted ec with the	assisted ec with the	-	-	NO
4864760	26912723	JFXD	PLoS52	designed the study and prepared the manuscript	designed the study and prepared the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4864760	26912723	JTPY	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
4864760	26912723	TDD	PLoS52	designed the study and prepared the manuscript|performed the experiments	designed the study and prepared the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4864760	26912723	TDD	PLoS52	designed the study and prepared the manuscript|performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
1939878	17710148	GH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1939878	17710148	GH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1939878	17710148	GH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1939878	17710148	GH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1939878	17710148	GJ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1939878	17710148	GJ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1939878	17710148	GJ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1939878	17710148	LG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1939878	17710148	LG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1939878	17710148	LG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1939878	17710148	LG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415932	25928226	EL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415932	25928226	EL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415932	25928226	EL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415932	25928226	EL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415932	25928226	EL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415932	25928226	HA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415932	25928226	HA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415932	25928226	HA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415932	25928226	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415932	25928226	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415932	25928226	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415932	25928226	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415932	25928226	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415932	25928226	LJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415932	25928226	LJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415932	25928226	LJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415932	25928226	PB	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415932	25928226	PB	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415932	25928226	RS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415932	25928226	RS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415932	25928226	RS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5767787	29367857	BB	2	performed phylogenic analysis of the rlv bacteria|collected nodules and performed analyses of bacterial occupancy	performed phylogenic analysis of the rlv bacteria	Performed the experiments	Investigation	YES
5767787	29367857	BB	2	performed phylogenic analysis of the rlv bacteria|collected nodules and performed analyses of bacterial occupancy	collected nodules and performed analyses of bacterial occupancy	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5767787	29367857	CD	2	provided seeds and information on the pea collection, and contributed to phenotypic data acquisition	provided seeds and information on the pea collection, and contributed to phenotypic data acquisition	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5767787	29367857	DV	2	contributed to statistical analysis of the data	contributed to statistical analysis of the data	Analyzed the data	Formal analysis	YES
5767787	29367857	GD	2	contributed to the conception of the study and the design of the pea collection	contributed to the conception of the study and the design of the pea collection	Conceived and designed the experiments	Conceptualization|Methodology	YES
5767787	29367857	JB	2	contributed to the conception of the study and coordinated the genotyping of the pea collection	contributed to the conception of the study and coordinated the genotyping of the pea collection	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Project administration	YES
5767787	29367857	KH-G	2	participated in greenhouse experiments and contributed to phenotypic plant data acquisition|collected nodules and performed analyses of bacterial occupancy	participated in greenhouse experiments and contributed to phenotypic plant data acquisition	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5767787	29367857	KH-G	2	participated in greenhouse experiments and contributed to phenotypic plant data acquisition|collected nodules and performed analyses of bacterial occupancy	collected nodules and performed analyses of bacterial occupancy	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5767787	29367857	MC-M	2	provided seeds and information on the pea collection, and contributed to phenotypic data acquisition	provided seeds and information on the pea collection, and contributed to phenotypic data acquisition	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5767787	29367857	ML	2	collected nodules and performed analyses of bacterial occupancy|wrote the manuscript which was revised and accepted by all authors	collected nodules and performed analyses of bacterial occupancy	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5767787	29367857	ML	2	collected nodules and performed analyses of bacterial occupancy|wrote the manuscript which was revised and accepted by all authors	wrote the manuscript which was revised and accepted by all authors	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5767787	29367857	MP	2	performed phylogenic analysis of the rlv bacteria	performed phylogenic analysis of the rlv bacteria	Performed the experiments	Investigation	YES
5767787	29367857	MS	2	performed pea collection genetic structure analyses	performed pea collection genetic structure analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5767787	29367857	PT	2	collected nodules and performed analyses of bacterial occupancy	collected nodules and performed analyses of bacterial occupancy	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5767787	29367857	VA	2	participated in greenhouse experiments and contributed to phenotypic plant data acquisition	participated in greenhouse experiments and contributed to phenotypic plant data acquisition	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5767787	29367857	VB	2	contributed to the design of the pea collection, coordinated and participated in greenhouse experiments and plant phenotypic data acquisition, performed plant phenotypic data analyses and interpretation|wrote the manuscript which was revised and accepted by all authors	contributed to the design of the pea collection, coordinated and participated in greenhouse experiments and plant phenotypic data acquisition, performed plant phenotypic data analyses and interpretation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Methodology|Project administration|Resources	YES
5767787	29367857	VB	2	contributed to the design of the pea collection, coordinated and participated in greenhouse experiments and plant phenotypic data acquisition, performed plant phenotypic data analyses and interpretation|wrote the manuscript which was revised and accepted by all authors	wrote the manuscript which was revised and accepted by all authors	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5364124	28337735	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5364124	28337735	DZ	2	participated in critically reviewing and revising the manuscript	participated in critically reviewing and revising the manuscript	Wrote the paper	Writing - Review & Editing	YES
5364124	28337735	HH	2	participated in critically reviewing and revising the manuscript	participated in critically reviewing and revising the manuscript	Wrote the paper	Writing - Review & Editing	YES
5364124	28337735	MG	2	participated in critically reviewing and revising the manuscript	participated in critically reviewing and revising the manuscript	Wrote the paper	Writing - Review & Editing	YES
5364124	28337735	RL	2	participated in critically reviewing and revising the manuscript	participated in critically reviewing and revising the manuscript	Wrote the paper	Writing - Review & Editing	YES
5364124	28337735	YL	2	participated in critically reviewing and revising the manuscript	participated in critically reviewing and revising the manuscript	Wrote the paper	Writing - Review & Editing	YES
5364124	28337735	YLH	2	performed the experimental work and prepared the manuscript	performed the experimental work and prepared the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5683603	29132311	All the authors	2	read the manuscript and gave the final approval of the version to be published|agreed to be accountable for all aspects of the work	read the manuscript and gave the final approval of the version to be published	-	-	NO
5683603	29132311	All the authors	2	read the manuscript and gave the final approval of the version to be published|agreed to be accountable for all aspects of the work	agreed to be accountable for all aspects of the work	-	-	NO
5683603	29132311	CSX	2	organized the collection of samples and phenotypes	organized the collection of samples and phenotypes	Performed the experiments	Investigation	YES
5683603	29132311	DFZ	2	contributed to the conception and design|revised it	contributed to the conception and design	Conceived and designed the experiments	Conceptualization	YES
5683603	29132311	DFZ	2	contributed to the conception and design|revised it	revised it	Wrote the paper	Writing - Review & Editing	YES
5683603	29132311	HPD	2	organized the collection of samples and phenotypes	organized the collection of samples and phenotypes	Performed the experiments	Investigation	YES
5683603	29132311	LH	2	interpreted the analysis results|revised it	interpreted the analysis results	Analyzed the data	Formal analysis	YES
5683603	29132311	LH	2	interpreted the analysis results|revised it	revised it	Wrote the paper	Writing - Review & Editing	YES
5683603	29132311	QHT	2	revised it	revised it	Wrote the paper	Writing - Review & Editing	YES
5683603	29132311	SXL	2	revised it	revised it	Wrote the paper	Writing - Review & Editing	YES
5683603	29132311	WJJ	2	contributed to sample data and sequencing data management	contributed to sample data and sequencing data management	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Investigation|Resources	YES
5683603	29132311	WJW	2	contributed to the conception and design|contributed to sample data and sequencing data management|interpreted the analysis results	contributed to the conception and design	Conceived and designed the experiments	Conceptualization	YES
5683603	29132311	WJW	2	contributed to the conception and design|contributed to sample data and sequencing data management|interpreted the analysis results	contributed to sample data and sequencing data management	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Investigation|Resources	YES
5683603	29132311	WJW	2	contributed to the conception and design|contributed to sample data and sequencing data management|interpreted the analysis results	interpreted the analysis results	Analyzed the data	Formal analysis	YES
5683603	29132311	YLW	2	interpreted the analysis results	interpreted the analysis results	Analyzed the data	Formal analysis	YES
5457539	28588427	FY	2	performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
5457539	28588427	LZ	2	were responsible for the study design and for data collection and interpretation|were responsible for the study design and for data collection and interpretation|performed the statistical analysis|drafted the manuscript	were responsible for the study design and for data collection and interpretation	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5457539	28588427	LZ	2	were responsible for the study design and for data collection and interpretation|were responsible for the study design and for data collection and interpretation|performed the statistical analysis|drafted the manuscript	were responsible for the study design and for data collection and interpretation	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5457539	28588427	LZ	2	were responsible for the study design and for data collection and interpretation|were responsible for the study design and for data collection and interpretation|performed the statistical analysis|drafted the manuscript	performed the statistical analysis	Analyzed the data	Formal analysis	YES
5457539	28588427	LZ	2	were responsible for the study design and for data collection and interpretation|were responsible for the study design and for data collection and interpretation|performed the statistical analysis|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5457539	28588427	QH	2	performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
5457539	28588427	WY	2	were responsible for the study design and for data collection and interpretation	were responsible for the study design and for data collection and interpretation	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5457539	28588427	YS	2	performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
4415933	25928715	AF	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4415933	25928715	AP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415933	25928715	AP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415933	25928715	AP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415933	25928715	M. Cignarelli	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415933	25928715	M. Cignarelli	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415933	25928715	M. Copetti	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4415933	25928715	OL	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415933	25928715	OL	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415933	25928715	SDC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415933	25928715	SDC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415933	25928715	SDC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415933	25928715	VT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415933	25928715	VT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415933	25928715	VT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1939879	17710130	AM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1939879	17710130	AM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1939879	17710130	AM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1939879	17710130	AS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1939879	17710130	AS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1939879	17710130	AS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1939879	17710130	AT	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1939879	17710130	AT	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1939879	17710130	AT	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1939879	17710130	ES	PLoS5	Performed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1939879	17710130	ES	PLoS5	Performed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1939879	17710130	ES	PLoS5	Performed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1939879	17710130	ES	PLoS5	Performed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1939879	17710130	ES	PLoS5	Performed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1939879	17710130	JS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1939879	17710130	JS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1939879	17710130	JS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1939879	17710130	MS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1939879	17710130	MS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1939879	17710130	TS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1939879	17710130	TS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5767846	29367855	GZ	2	designed the study and wrote the manuscript	designed the study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5767846	29367855	JW	2	discussed the results and revised the manuscript	discussed the results and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5767846	29367855	LilZ	2	participated in experiments	participated in experiments	Performed the experiments	Investigation	YES
5767846	29367855	LinZ	2	discussed the results and revised the manuscript	discussed the results and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5767846	29367855	NN	2	discussed the results and revised the manuscript	discussed the results and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5767846	29367855	QS	2	participated in experiments	participated in experiments	Performed the experiments	Investigation	YES
5767846	29367855	SM	2	discussed the results and revised the manuscript	discussed the results and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5767846	29367855	SW	2	designed the study and wrote the manuscript|participated in experiments	designed the study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5767846	29367855	SW	2	designed the study and wrote the manuscript|participated in experiments	participated in experiments	Performed the experiments	Investigation	YES
5767846	29367855	YY	2	discussed the results and revised the manuscript	discussed the results and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5767846	29367855	YaZ	2	participated in experiments	participated in experiments	Performed the experiments	Investigation	YES
5767846	29367855	YiZ	2	participated in experiments	participated in experiments	Performed the experiments	Investigation	YES
5767846	29367855	ZC	2	participated in experiments	participated in experiments	Performed the experiments	Investigation	YES
5767846	29367855	ZF	2	participated in experiments	participated in experiments	Performed the experiments	Investigation	YES
5767846	29367855	ZH	2	discussed the results and revised the manuscript	discussed the results and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5366992	28342171	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5366992	28342171	KP	2	helped design the experiments and draft the manuscript|conceived the study	helped design the experiments and draft the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5366992	28342171	KP	2	helped design the experiments and draft the manuscript|conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5366992	28342171	PM	2	performed the elisa experiments and analysis|helped design the experiments and draft the manuscript	performed the elisa experiments and analysis	Performed the experiments	Investigation	YES
5366992	28342171	PM	2	performed the elisa experiments and analysis|helped design the experiments and draft the manuscript	helped design the experiments and draft the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5366992	28342171	RA	2	designed and performed the experiments and helped draft the manuscript	designed and performed the experiments and helped draft the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5366992	28342171	RS	2	helped design the experiments and draft the manuscript|conceived the study	helped design the experiments and draft the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5366992	28342171	RS	2	helped design the experiments and draft the manuscript|conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4620393	26543869	Mei Zheng	2	contributed to conception and design, carrying out data analysis, and drafting the paper	contributed to conception and design, carrying out data analysis, and drafting the paper	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Resources|Writing - Original Draft	YES
1940310	17710126	C-TC	PLoS5	Screened pharmaceutical companies and determined the formulation	Screened pharmaceutical companies and determined the formulation	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
1940310	17710126	C-YH	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1940310	17710126	J-MC	PLoS5	Analyzed the data|Designed repeated measurement analyses|Performed repeated measurement analyses|Wrote statistical report	Analyzed the data	Analyzed the data	Formal analysis	YES
1940310	17710126	J-MC	PLoS5	Analyzed the data|Designed repeated measurement analyses|Performed repeated measurement analyses|Wrote statistical report	Designed repeated measurement analyses	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
1940310	17710126	J-MC	PLoS5	Analyzed the data|Designed repeated measurement analyses|Performed repeated measurement analyses|Wrote statistical report	Performed repeated measurement analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
1940310	17710126	J-MC	PLoS5	Analyzed the data|Designed repeated measurement analyses|Performed repeated measurement analyses|Wrote statistical report	Wrote statistical report	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
1940310	17710126	J-YL	PLoS5	Contributed to the study design on dosage regimen|Had the idea of sealing capsules to mask the aroma|Ultrasound examination|Performed blood draw|Determined the classification of dysmenorrhoea|Prescribed and handed out ibuprofen|Attended adverse reactions|Revised online diary	Contributed to the study design on dosage regimen	Conceived and designed the experiments	Methodology	YES
1940310	17710126	J-YL	PLoS5	Contributed to the study design on dosage regimen|Had the idea of sealing capsules to mask the aroma|Ultrasound examination|Performed blood draw|Determined the classification of dysmenorrhoea|Prescribed and handed out ibuprofen|Attended adverse reactions|Revised online diary	Had the idea of sealing capsules to mask the aroma	Conceived and designed the experiments	Conceptualization	YES
1940310	17710126	J-YL	PLoS5	Contributed to the study design on dosage regimen|Had the idea of sealing capsules to mask the aroma|Ultrasound examination|Performed blood draw|Determined the classification of dysmenorrhoea|Prescribed and handed out ibuprofen|Attended adverse reactions|Revised online diary	Ultrasound examination	Performed the experiments	Investigation	YES
1940310	17710126	J-YL	PLoS5	Contributed to the study design on dosage regimen|Had the idea of sealing capsules to mask the aroma|Ultrasound examination|Performed blood draw|Determined the classification of dysmenorrhoea|Prescribed and handed out ibuprofen|Attended adverse reactions|Revised online diary	Performed blood draw	Performed the experiments	Investigation	YES
1940310	17710126	J-YL	PLoS5	Contributed to the study design on dosage regimen|Had the idea of sealing capsules to mask the aroma|Ultrasound examination|Performed blood draw|Determined the classification of dysmenorrhoea|Prescribed and handed out ibuprofen|Attended adverse reactions|Revised online diary	Determined the classification of dysmenorrhoea	-	-	NO
1940310	17710126	J-YL	PLoS5	Contributed to the study design on dosage regimen|Had the idea of sealing capsules to mask the aroma|Ultrasound examination|Performed blood draw|Determined the classification of dysmenorrhoea|Prescribed and handed out ibuprofen|Attended adverse reactions|Revised online diary	Prescribed and handed out ibuprofen	-	-	NO
1940310	17710126	J-YL	PLoS5	Contributed to the study design on dosage regimen|Had the idea of sealing capsules to mask the aroma|Ultrasound examination|Performed blood draw|Determined the classification of dysmenorrhoea|Prescribed and handed out ibuprofen|Attended adverse reactions|Revised online diary	Attended adverse reactions	-	-	NO
1940310	17710126	J-YL	PLoS5	Contributed to the study design on dosage regimen|Had the idea of sealing capsules to mask the aroma|Ultrasound examination|Performed blood draw|Determined the classification of dysmenorrhoea|Prescribed and handed out ibuprofen|Attended adverse reactions|Revised online diary	Revised online diary	Wrote the paper	Writing - Review & Editing	YES
1940310	17710126	K-SL	PLoS5	Contributed to the study design on dosage regimen|Attended adverse reactions|Revised online diary	Contributed to the study design on dosage regimen	Conceived and designed the experiments	Methodology	YES
1940310	17710126	K-SL	PLoS5	Contributed to the study design on dosage regimen|Attended adverse reactions|Revised online diary	Attended adverse reactions	-	-	NO
1940310	17710126	K-SL	PLoS5	Contributed to the study design on dosage regimen|Attended adverse reactions|Revised online diary	Revised online diary	Wrote the paper	Writing - Review & Editing	YES
1940310	17710126	K-YL	PLoS5	Designed repeated measurement analyses	Designed repeated measurement analyses	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
1940310	17710126	L-HW	PLoS5	Prescribed and handed out the study products	Prescribed and handed out the study products	-	-	NO
1940310	17710126	LLY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Initiated the investigations|Proposed preliminary study design|Wrote protocol|Obtained funding|Recruited subjects|Organized the team|Coordinated study execution|Contributed to the study design on dosage regimen|Screened pharmaceutical companies and determined the formulation|Initiated and developed electronic data capture system|Collected, managed, and analyzed data|Wrote the report	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1940310	17710126	LLY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Initiated the investigations|Proposed preliminary study design|Wrote protocol|Obtained funding|Recruited subjects|Organized the team|Coordinated study execution|Contributed to the study design on dosage regimen|Screened pharmaceutical companies and determined the formulation|Initiated and developed electronic data capture system|Collected, managed, and analyzed data|Wrote the report	Performed the experiments	Performed the experiments	Investigation	YES
1940310	17710126	LLY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Initiated the investigations|Proposed preliminary study design|Wrote protocol|Obtained funding|Recruited subjects|Organized the team|Coordinated study execution|Contributed to the study design on dosage regimen|Screened pharmaceutical companies and determined the formulation|Initiated and developed electronic data capture system|Collected, managed, and analyzed data|Wrote the report	Analyzed the data	Analyzed the data	Formal analysis	YES
1940310	17710126	LLY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Initiated the investigations|Proposed preliminary study design|Wrote protocol|Obtained funding|Recruited subjects|Organized the team|Coordinated study execution|Contributed to the study design on dosage regimen|Screened pharmaceutical companies and determined the formulation|Initiated and developed electronic data capture system|Collected, managed, and analyzed data|Wrote the report	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1940310	17710126	LLY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Initiated the investigations|Proposed preliminary study design|Wrote protocol|Obtained funding|Recruited subjects|Organized the team|Coordinated study execution|Contributed to the study design on dosage regimen|Screened pharmaceutical companies and determined the formulation|Initiated and developed electronic data capture system|Collected, managed, and analyzed data|Wrote the report	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1940310	17710126	LLY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Initiated the investigations|Proposed preliminary study design|Wrote protocol|Obtained funding|Recruited subjects|Organized the team|Coordinated study execution|Contributed to the study design on dosage regimen|Screened pharmaceutical companies and determined the formulation|Initiated and developed electronic data capture system|Collected, managed, and analyzed data|Wrote the report	Initiated the investigations	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
1940310	17710126	LLY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Initiated the investigations|Proposed preliminary study design|Wrote protocol|Obtained funding|Recruited subjects|Organized the team|Coordinated study execution|Contributed to the study design on dosage regimen|Screened pharmaceutical companies and determined the formulation|Initiated and developed electronic data capture system|Collected, managed, and analyzed data|Wrote the report	Proposed preliminary study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
1940310	17710126	LLY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Initiated the investigations|Proposed preliminary study design|Wrote protocol|Obtained funding|Recruited subjects|Organized the team|Coordinated study execution|Contributed to the study design on dosage regimen|Screened pharmaceutical companies and determined the formulation|Initiated and developed electronic data capture system|Collected, managed, and analyzed data|Wrote the report	Wrote protocol	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
1940310	17710126	LLY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Initiated the investigations|Proposed preliminary study design|Wrote protocol|Obtained funding|Recruited subjects|Organized the team|Coordinated study execution|Contributed to the study design on dosage regimen|Screened pharmaceutical companies and determined the formulation|Initiated and developed electronic data capture system|Collected, managed, and analyzed data|Wrote the report	Obtained funding	-	Funding acquisition	YES
1940310	17710126	LLY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Initiated the investigations|Proposed preliminary study design|Wrote protocol|Obtained funding|Recruited subjects|Organized the team|Coordinated study execution|Contributed to the study design on dosage regimen|Screened pharmaceutical companies and determined the formulation|Initiated and developed electronic data capture system|Collected, managed, and analyzed data|Wrote the report	Recruited subjects	Performed the experiments	Investigation	YES
1940310	17710126	LLY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Initiated the investigations|Proposed preliminary study design|Wrote protocol|Obtained funding|Recruited subjects|Organized the team|Coordinated study execution|Contributed to the study design on dosage regimen|Screened pharmaceutical companies and determined the formulation|Initiated and developed electronic data capture system|Collected, managed, and analyzed data|Wrote the report	Organized the team	-	-	NO
1940310	17710126	LLY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Initiated the investigations|Proposed preliminary study design|Wrote protocol|Obtained funding|Recruited subjects|Organized the team|Coordinated study execution|Contributed to the study design on dosage regimen|Screened pharmaceutical companies and determined the formulation|Initiated and developed electronic data capture system|Collected, managed, and analyzed data|Wrote the report	Coordinated study execution	Performed the experiments	Investigation|Project administration	YES
1940310	17710126	LLY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Initiated the investigations|Proposed preliminary study design|Wrote protocol|Obtained funding|Recruited subjects|Organized the team|Coordinated study execution|Contributed to the study design on dosage regimen|Screened pharmaceutical companies and determined the formulation|Initiated and developed electronic data capture system|Collected, managed, and analyzed data|Wrote the report	Contributed to the study design on dosage regimen	Conceived and designed the experiments	Methodology	YES
1940310	17710126	LLY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Initiated the investigations|Proposed preliminary study design|Wrote protocol|Obtained funding|Recruited subjects|Organized the team|Coordinated study execution|Contributed to the study design on dosage regimen|Screened pharmaceutical companies and determined the formulation|Initiated and developed electronic data capture system|Collected, managed, and analyzed data|Wrote the report	Screened pharmaceutical companies and determined the formulation	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
1940310	17710126	LLY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Initiated the investigations|Proposed preliminary study design|Wrote protocol|Obtained funding|Recruited subjects|Organized the team|Coordinated study execution|Contributed to the study design on dosage regimen|Screened pharmaceutical companies and determined the formulation|Initiated and developed electronic data capture system|Collected, managed, and analyzed data|Wrote the report	Initiated and developed electronic data capture system	Conceived and designed the experiments|Performed the experiments	Conceptualization|Methodology	YES
1940310	17710126	LLY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Initiated the investigations|Proposed preliminary study design|Wrote protocol|Obtained funding|Recruited subjects|Organized the team|Coordinated study execution|Contributed to the study design on dosage regimen|Screened pharmaceutical companies and determined the formulation|Initiated and developed electronic data capture system|Collected, managed, and analyzed data|Wrote the report	Collected, managed, and analyzed data	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
1940310	17710126	LLY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Initiated the investigations|Proposed preliminary study design|Wrote protocol|Obtained funding|Recruited subjects|Organized the team|Coordinated study execution|Contributed to the study design on dosage regimen|Screened pharmaceutical companies and determined the formulation|Initiated and developed electronic data capture system|Collected, managed, and analyzed data|Wrote the report	Wrote the report	Wrote the paper	Writing - Original Draft	YES
1940310	17710126	T-FT	PLoS5	Revised online diary|Prescribed and handed out the study products	Revised online diary	Wrote the paper	Writing - Review & Editing	YES
1940310	17710126	T-FT	PLoS5	Revised online diary|Prescribed and handed out the study products	Prescribed and handed out the study products	-	-	NO
1940310	17710126	Y-SL	PLoS5	Ultrasound examination|Performed blood draw|Prescribed and handed out ibuprofen|Revised online diary	Ultrasound examination	Performed the experiments	Investigation	YES
1940310	17710126	Y-SL	PLoS5	Ultrasound examination|Performed blood draw|Prescribed and handed out ibuprofen|Revised online diary	Performed blood draw	Performed the experiments	Investigation	YES
1940310	17710126	Y-SL	PLoS5	Ultrasound examination|Performed blood draw|Prescribed and handed out ibuprofen|Revised online diary	Prescribed and handed out ibuprofen	-	-	NO
1940310	17710126	Y-SL	PLoS5	Ultrasound examination|Performed blood draw|Prescribed and handed out ibuprofen|Revised online diary	Revised online diary	Wrote the paper	Writing - Review & Editing	YES
5688405	29143596	DH	1	Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5688405	29143596	NE	1	Conceived the study|Wrote the manuscript	Conceived the study	Conceived and designed the experiments	Conceptualization	YES
5688405	29143596	NE	1	Conceived the study|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5688405	29143596	NV	1	Performed review|Wrote the manuscript	Performed review	Performed the experiments	Investigation	YES
5688405	29143596	NV	1	Performed review|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5688405	29143596	YP	1	Conceived the study	Conceived the study	Conceived and designed the experiments	Conceptualization	YES
4415934	25927925	AT	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415934	25927925	KP	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415934	25927925	NP	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4415934	25927925	NP	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415934	25927925	NW	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415934	25927925	PS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415934	25927925	PS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415934	25927925	PS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415934	25927925	PS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415934	25927925	PS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415934	25927925	PV	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4415934	25927925	PV	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415934	25927925	RW	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415934	25927925	SO	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415934	25927925	SV	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415934	25927925	TT	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415934	25927925	YP	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415934	25927925	YP	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5465465	28603468	ACF	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5465465	28603468	All authors	2	critically revised and approved the final manuscript	critically revised and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5465465	28603468	CJM	2	designed the study|conducted the experiment|analyzed the result|wrote the manuscript|is responsible for the final content of the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5465465	28603468	CJM	2	designed the study|conducted the experiment|analyzed the result|wrote the manuscript|is responsible for the final content of the manuscript	conducted the experiment	Performed the experiments	Investigation	YES
5465465	28603468	CJM	2	designed the study|conducted the experiment|analyzed the result|wrote the manuscript|is responsible for the final content of the manuscript	analyzed the result	Analyzed the data	Formal analysis	YES
5465465	28603468	CJM	2	designed the study|conducted the experiment|analyzed the result|wrote the manuscript|is responsible for the final content of the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5465465	28603468	CJM	2	designed the study|conducted the experiment|analyzed the result|wrote the manuscript|is responsible for the final content of the manuscript	is responsible for the final content of the manuscript	-	-	NO
5465465	28603468	DCS	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5465465	28603468	KA	2	analyzed the result	analyzed the result	Analyzed the data	Formal analysis	YES
5465465	28603468	NZ	2	analyzed the result	analyzed the result	Analyzed the data	Formal analysis	YES
5465465	28603468	RFD	2	conducted the experiment|analyzed the result	conducted the experiment	Performed the experiments	Investigation	YES
5465465	28603468	RFD	2	conducted the experiment|analyzed the result	analyzed the result	Analyzed the data	Formal analysis	YES
5465465	28603468	SDP	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5465465	28603468	SMM	2	conducted the experiment	conducted the experiment	Performed the experiments	Investigation	YES
5769382	29375611	BR	2	performed the data synthesis and analysis|brought to completion with significant input and criticism from the other authors	performed the data synthesis and analysis	Analyzed the data	Formal analysis	YES
5769382	29375611	BR	2	performed the data synthesis and analysis|brought to completion with significant input and criticism from the other authors	brought to completion with significant input and criticism from the other authors	-	-	NO
5769382	29375611	EB	2	performed the data synthesis and analysis|performed the field and lab work	performed the data synthesis and analysis	Analyzed the data	Formal analysis	YES
5769382	29375611	EB	2	performed the data synthesis and analysis|performed the field and lab work	performed the field and lab work	Performed the experiments	Investigation	YES
5769382	29375611	EM	2	were responsible for the conceptualization of the treatments and the design of the experiments|performed the field and lab work	were responsible for the conceptualization of the treatments and the design of the experiments	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
5769382	29375611	EM	2	were responsible for the conceptualization of the treatments and the design of the experiments|performed the field and lab work	performed the field and lab work	Performed the experiments	Investigation	YES
5769382	29375611	GB	2	were responsible for the conceptualization of the treatments and the design of the experiments	were responsible for the conceptualization of the treatments and the design of the experiments	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
5769382	29375611	KM	2	were responsible for the conceptualization of the treatments and the design of the experiments	were responsible for the conceptualization of the treatments and the design of the experiments	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
5769382	29375611	LB	2	were responsible for the conceptualization of the treatments and the design of the experiments	were responsible for the conceptualization of the treatments and the design of the experiments	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
1940311	17710152	AA	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1940311	17710152	AK	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1940311	17710152	DJ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1940311	17710152	EB	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1940311	17710152	MM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1940311	17710152	PW	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1940311	17710152	SK	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1940311	17710152	SM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1940311	17710152	SZ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4868951	26988032	AAT	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4868951	26988032	All authors	PLoS52	designed experiments and interpreted data	designed experiments and interpreted data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
4868951	26988032	CD	PLoS52	performed experiments|wrote the paper	performed experiments	Performed the experiments	Investigation	YES
4868951	26988032	CD	PLoS52	performed experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4868951	26988032	F-FT	PLoS52	performed experiments|wrote the paper	performed experiments	Performed the experiments	Investigation	YES
4868951	26988032	F-FT	PLoS52	performed experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4868951	26988032	KS	PLoS52	performed experiments	performed experiments	Performed the experiments	Investigation	YES
4868951	26988032	M-AA	PLoS52	performed experiments|wrote the paper	performed experiments	Performed the experiments	Investigation	YES
4868951	26988032	M-AA	PLoS52	performed experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4868951	26988032	MB	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415935	25928357	BKAO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Produced the conditioning chambers and the cannulae|Revised the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415935	25928357	BKAO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Produced the conditioning chambers and the cannulae|Revised the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4415935	25928357	BKAO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Produced the conditioning chambers and the cannulae|Revised the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4415935	25928357	BKAO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Produced the conditioning chambers and the cannulae|Revised the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415935	25928357	BKAO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Produced the conditioning chambers and the cannulae|Revised the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415935	25928357	BKAO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Produced the conditioning chambers and the cannulae|Revised the manuscript	Produced the conditioning chambers and the cannulae	-	-	NO
4415935	25928357	BKAO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Produced the conditioning chambers and the cannulae|Revised the manuscript	Revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4415935	25928357	EMAJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Produced the conditioning chambers and the cannulae|Obtained permission for use of rats brain figures|Revised the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415935	25928357	EMAJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Produced the conditioning chambers and the cannulae|Obtained permission for use of rats brain figures|Revised the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4415935	25928357	EMAJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Produced the conditioning chambers and the cannulae|Obtained permission for use of rats brain figures|Revised the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4415935	25928357	EMAJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Produced the conditioning chambers and the cannulae|Obtained permission for use of rats brain figures|Revised the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415935	25928357	EMAJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Produced the conditioning chambers and the cannulae|Obtained permission for use of rats brain figures|Revised the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415935	25928357	EMAJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Produced the conditioning chambers and the cannulae|Obtained permission for use of rats brain figures|Revised the manuscript	Produced the conditioning chambers and the cannulae	-	-	NO
4415935	25928357	EMAJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Produced the conditioning chambers and the cannulae|Obtained permission for use of rats brain figures|Revised the manuscript	Obtained permission for use of rats brain figures	-	Visualization	YES
4415935	25928357	EMAJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Produced the conditioning chambers and the cannulae|Obtained permission for use of rats brain figures|Revised the manuscript	Revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4415935	25928357	GFX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Produced the conditioning chambers and the cannulae|Revised the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415935	25928357	GFX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Produced the conditioning chambers and the cannulae|Revised the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4415935	25928357	GFX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Produced the conditioning chambers and the cannulae|Revised the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4415935	25928357	GFX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Produced the conditioning chambers and the cannulae|Revised the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415935	25928357	GFX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Produced the conditioning chambers and the cannulae|Revised the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415935	25928357	GFX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Produced the conditioning chambers and the cannulae|Revised the manuscript	Produced the conditioning chambers and the cannulae	-	-	NO
4415935	25928357	GFX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Produced the conditioning chambers and the cannulae|Revised the manuscript	Revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5688409	29143594	DJB	2	designed the study|drafted the initial manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5688409	29143594	DJB	2	designed the study|drafted the initial manuscript	drafted the initial manuscript	Wrote the paper	Writing - Original Draft	YES
5688409	29143594	FM	2	conducted the study, and provided feedback on the manuscript	conducted the study, and provided feedback on the manuscript	Performed the experiments	Investigation	YES
5688409	29143594	IDP	2	conducted the study, and provided feedback on the manuscript	conducted the study, and provided feedback on the manuscript	Performed the experiments	Investigation	YES
5688409	29143594	JK	2	conducted the study, and provided feedback on the manuscript	conducted the study, and provided feedback on the manuscript	Performed the experiments	Investigation	YES
5688409	29143594	KJA	2	contributed to the study design and provided feedback on the manuscript	contributed to the study design and provided feedback on the manuscript	Conceived and designed the experiments	Methodology	YES
5688409	29143594	LOK	2	conducted the study, and provided feedback on the manuscript	conducted the study, and provided feedback on the manuscript	Performed the experiments	Investigation	YES
5688409	29143594	LRG	2	contributed to the study design and provided feedback on the manuscript	contributed to the study design and provided feedback on the manuscript	Conceived and designed the experiments	Methodology	YES
5688409	29143594	NB	2	contributed to the study design and provided feedback on the manuscript	contributed to the study design and provided feedback on the manuscript	Conceived and designed the experiments	Methodology	YES
5688409	29143594	NE	2	designed the study|drafted the initial manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5688409	29143594	NE	2	designed the study|drafted the initial manuscript	drafted the initial manuscript	Wrote the paper	Writing - Original Draft	YES
5688409	29143594	OT	2	conducted the study, and provided feedback on the manuscript	conducted the study, and provided feedback on the manuscript	Performed the experiments	Investigation	YES
5688409	29143594	XY	2	designed the study|drafted the initial manuscript|conducted the study, and provided feedback on the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5688409	29143594	XY	2	designed the study|drafted the initial manuscript|conducted the study, and provided feedback on the manuscript	drafted the initial manuscript	Wrote the paper	Writing - Original Draft	YES
5688409	29143594	XY	2	designed the study|drafted the initial manuscript|conducted the study, and provided feedback on the manuscript	conducted the study, and provided feedback on the manuscript	Performed the experiments	Investigation	YES
5688409	29143594	YPP	2	contributed to the study design and provided feedback on the manuscript	contributed to the study design and provided feedback on the manuscript	Conceived and designed the experiments	Methodology	YES
5366994	28342170	All	2	the data are presented in the main paper or additional file 1	the data are presented in the main paper or additional file 1	-	-	NO
5366994	28342170	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5366994	28342170	KML	2	designed the study, analysed and interpreted the data, and wrote the manuscript	designed the study, analysed and interpreted the data, and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5366994	28342170	TWN	2	designed the study, analysed and interpreted the data, and wrote the manuscript|conducted the study and collected the data	designed the study, analysed and interpreted the data, and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5366994	28342170	TWN	2	designed the study, analysed and interpreted the data, and wrote the manuscript|conducted the study and collected the data	conducted the study and collected the data	Performed the experiments	Investigation	YES
5366994	28342170	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5366994	28342170	WLC	2	conducted the study and collected the data	conducted the study and collected the data	Performed the experiments	Investigation	YES
5769460	29375598	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5769460	29375598	C-YK	PLoS52	performed the experiments|analyzed the data|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5769460	29375598	C-YK	PLoS52	performed the experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5769460	29375598	C-YK	PLoS52	performed the experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5769460	29375598	G-LW	PLoS52	analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5769460	29375598	G-LW	PLoS52	analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5769460	29375598	GS	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5769460	29375598	J-SJ	PLoS52	analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5769460	29375598	J-SJ	PLoS52	analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5769460	29375598	KV	PLoS52	performed the experiments|analyzed the data|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5769460	29375598	KV	PLoS52	performed the experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5769460	29375598	KV	PLoS52	performed the experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5769460	29375598	S-KL	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5769460	29375598	S-WL	PLoS52	analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5769460	29375598	S-WL	PLoS52	analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5769460	29375598	TH	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5769460	29375598	Y-SS	PLoS52	analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5769460	29375598	Y-SS	PLoS52	analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5469049	28615996	Editors-In Chief	2	to represent the official position of the international society of sports nutrition	to represent the official position of the international society of sports nutrition	-	-	NO
5469049	28615996	RBK	2	prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
1940312	17710132	JC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1940312	17710132	RW	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1940312	17710132	RW	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1940312	17710132	SW	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1940312	17710132	TL	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1940312	17710132	WH	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4883027	27220848	AF	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
4883027	27220848	DS	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
4883027	27220848	MR	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
4415936	25927611	AAB	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415936	25927611	AMD	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415936	25927611	AMR	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4415936	25927611	AVA	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415936	25927611	EGS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415936	25927611	EGS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415936	25927611	EGS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415936	25927611	ESK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4415936	25927611	IES	PLoS5	Contributed reagents/materials/analysis tools|Designed the software used in analysis	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415936	25927611	IES	PLoS5	Contributed reagents/materials/analysis tools|Designed the software used in analysis	Designed the software used in analysis	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
4415936	25927611	NNE	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4415936	25927611	OVP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415936	25927611	OVP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415936	25927611	OVP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415936	25927611	PGM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415936	25927611	VAK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5688435	29143592	AW	2	conceived and designed the study|contributed to data collection|analysed data and drafted the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5688435	29143592	AW	2	conceived and designed the study|contributed to data collection|analysed data and drafted the manuscript	contributed to data collection	Performed the experiments	Investigation	YES
5688435	29143592	AW	2	conceived and designed the study|contributed to data collection|analysed data and drafted the manuscript	analysed data and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5688435	29143592	All authors	2	contributed to interpretation of data, revised the article critically for important intellectual content and approved the final version of the manuscript	contributed to interpretation of data, revised the article critically for important intellectual content and approved the final version of the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
5688435	29143592	CC	2	contributed to data collection	contributed to data collection	Performed the experiments	Investigation	YES
5688435	29143592	GS	2	contributed to data collection	contributed to data collection	Performed the experiments	Investigation	YES
5688435	29143592	GW	2	conceived and designed the study|contributed to data collection	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5688435	29143592	GW	2	conceived and designed the study|contributed to data collection	contributed to data collection	Performed the experiments	Investigation	YES
5688435	29143592	LK	2	conceived and designed the study|contributed to data collection	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5688435	29143592	LK	2	conceived and designed the study|contributed to data collection	contributed to data collection	Performed the experiments	Investigation	YES
5688435	29143592	MB	2	contributed to data collection	contributed to data collection	Performed the experiments	Investigation	YES
5688435	29143592	MC	2	conceived and designed the study|contributed to data collection	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5688435	29143592	MC	2	conceived and designed the study|contributed to data collection	contributed to data collection	Performed the experiments	Investigation	YES
5688435	29143592	RE	2	conceived and designed the study|contributed to data collection	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5688435	29143592	RE	2	conceived and designed the study|contributed to data collection	contributed to data collection	Performed the experiments	Investigation	YES
5688435	29143592	SD	2	conceived and designed the study|contributed to data collection	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5688435	29143592	SD	2	conceived and designed the study|contributed to data collection	contributed to data collection	Performed the experiments	Investigation	YES
5688435	29143592	SH	2	conceived and designed the study|contributed to data collection|analysed data and drafted the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5688435	29143592	SH	2	conceived and designed the study|contributed to data collection|analysed data and drafted the manuscript	contributed to data collection	Performed the experiments	Investigation	YES
5688435	29143592	SH	2	conceived and designed the study|contributed to data collection|analysed data and drafted the manuscript	analysed data and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5688435	29143592	SR	2	contributed to data collection	contributed to data collection	Performed the experiments	Investigation	YES
5688435	29143592	YP	2	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5371168	28353158	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
1940313	17710154	AG	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1940313	17710154	AG	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1940313	17710154	BF	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1940313	17710154	BF	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1940313	17710154	BK	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1940313	17710154	BK	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1940313	17710154	FH	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1940313	17710154	FK	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1940313	17710154	KL	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1940313	17710154	KL	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1940313	17710154	MB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1940313	17710154	MB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1940313	17710154	MB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1940313	17710154	SE	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5469161	28615997	DM	2	undertook data interpretation and manuscript preparation	undertook data interpretation and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5469161	28615997	IB	2	undertook data interpretation and manuscript preparation	undertook data interpretation and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5469161	28615997	MCR	2	undertook data interpretation and manuscript preparation	undertook data interpretation and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5469161	28615997	MM	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5770357	29375594	AG	7	Designed research	Designed research	Conceived and designed the experiments	Methodology	YES
5770357	29375594	AM	7	Designed research|Wrote the paper	Designed research	Conceived and designed the experiments	Methodology	YES
5770357	29375594	AM	7	Designed research|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5770357	29375594	LS	7	Designed research|Performed research and analyzed data|Wrote the paper	Designed research	Conceived and designed the experiments	Methodology	YES
5770357	29375594	LS	7	Designed research|Performed research and analyzed data|Wrote the paper	Performed research and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5770357	29375594	LS	7	Designed research|Performed research and analyzed data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5770357	29375594	MM	7	Designed research	Designed research	Conceived and designed the experiments	Methodology	YES
5770357	29375594	NM	7	Designed research|Wrote the paper	Designed research	Conceived and designed the experiments	Methodology	YES
5770357	29375594	NM	7	Designed research|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5770357	29375594	PM	7	Designed research|Wrote the paper	Designed research	Conceived and designed the experiments	Methodology	YES
5770357	29375594	PM	7	Designed research|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5770357	29375594	TB	7	Designed research|Wrote the paper	Designed research	Conceived and designed the experiments	Methodology	YES
5770357	29375594	TB	7	Designed research|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4321135	25646517	All authors	2	contributed to the ideas and framework contained within the paper and edited the manuscript	contributed to the ideas and framework contained within the paper and edited the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
4884211	27225932	AV	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
4884211	27225932	BNV	PLoS52	conceived the study|developed and performed the experiments|analyzed the data|wrote the manuscript with contribution from the other authors	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4884211	27225932	BNV	PLoS52	conceived the study|developed and performed the experiments|analyzed the data|wrote the manuscript with contribution from the other authors	developed and performed the experiments	Performed the experiments	Investigation	YES
4884211	27225932	BNV	PLoS52	conceived the study|developed and performed the experiments|analyzed the data|wrote the manuscript with contribution from the other authors	analyzed the data	Analyzed the data	Formal analysis	YES
4884211	27225932	BNV	PLoS52	conceived the study|developed and performed the experiments|analyzed the data|wrote the manuscript with contribution from the other authors	wrote the manuscript with contribution from the other authors	Wrote the paper	Writing - Original Draft	YES
4884211	27225932	JAT	PLoS52	provided financial support and participated in the discussion	provided financial support and participated in the discussion	-	Funding acquisition	YES
4884211	27225932	JKT	PLoS52	developed and performed the experiments|analyzed the data|wrote the manuscript with contribution from the other authors	developed and performed the experiments	Performed the experiments	Investigation	YES
4884211	27225932	JKT	PLoS52	developed and performed the experiments|analyzed the data|wrote the manuscript with contribution from the other authors	analyzed the data	Analyzed the data	Formal analysis	YES
4884211	27225932	JKT	PLoS52	developed and performed the experiments|analyzed the data|wrote the manuscript with contribution from the other authors	wrote the manuscript with contribution from the other authors	Wrote the paper	Writing - Original Draft	YES
4884211	27225932	LS	PLoS52	conceived the study|analyzed the data|wrote the manuscript with contribution from the other authors	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4884211	27225932	LS	PLoS52	conceived the study|analyzed the data|wrote the manuscript with contribution from the other authors	analyzed the data	Analyzed the data	Formal analysis	YES
4884211	27225932	LS	PLoS52	conceived the study|analyzed the data|wrote the manuscript with contribution from the other authors	wrote the manuscript with contribution from the other authors	Wrote the paper	Writing - Original Draft	YES
4884211	27225932	NGS	PLoS52	developed and performed the experiments	developed and performed the experiments	Performed the experiments	Investigation	YES
4884211	27225932	NK-G	PLoS52	developed and performed the experiments	developed and performed the experiments	Performed the experiments	Investigation	YES
4884211	27225932	PM-R	PLoS52	developed and performed the experiments	developed and performed the experiments	Performed the experiments	Investigation	YES
4884211	27225932	SB	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
4884211	27225932	TN	PLoS52	developed and performed the experiments	developed and performed the experiments	Performed the experiments	Investigation	YES
4415937	25928887	EN	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4415937	25928887	FC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415937	25928887	FC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415937	25928887	FC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415937	25928887	FC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415937	25928887	FC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415937	25928887	LC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415937	25928887	LC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415937	25928887	LC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415937	25928887	LC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415937	25928887	LC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415937	25928887	LF	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4415937	25928887	LS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415937	25928887	LS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415937	25928887	MF	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4415937	25928887	UG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415937	25928887	UG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415937	25928887	UG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415937	25928887	UG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415937	25928887	UG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1940317	17712401	DC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1940317	17712401	DC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1940317	17712401	EL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Revised the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1940317	17712401	EL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Revised the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1940317	17712401	EL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Revised the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1940317	17712401	EL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Revised the paper	Revised the paper	Wrote the paper	Writing - Review & Editing	YES
1940317	17712401	GM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Conceived the movie	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1940317	17712401	GM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Conceived the movie	Performed the experiments	Performed the experiments	Investigation	YES
1940317	17712401	GM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Conceived the movie	Analyzed the data	Analyzed the data	Formal analysis	YES
1940317	17712401	GM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Conceived the movie	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1940317	17712401	GM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Conceived the movie	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1940317	17712401	GM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Conceived the movie	Conceived the movie	Conceived and designed the experiments	Conceptualization	YES
1940317	17712401	IB	PLoS5	Contributed reagents/materials/analysis tools|Performed the movie	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1940317	17712401	IB	PLoS5	Contributed reagents/materials/analysis tools|Performed the movie	Performed the movie	Performed the experiments	Investigation	YES
1940317	17712401	JJ	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1940317	17712401	JJ	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1940317	17712401	LH	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1940317	17712401	LH	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1940317	17712401	MR	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1940317	17712401	MR-R	PLoS5	Revised the paper	Revised the paper	Wrote the paper	Writing - Review & Editing	YES
1940317	17712401	RG	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1940317	17712401	RG	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1940317	17712401	SL	PLoS5	Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Wrote the paper|Performed the movie	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1940317	17712401	SL	PLoS5	Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Wrote the paper|Performed the movie	Performed the experiments	Performed the experiments	Investigation	YES
1940317	17712401	SL	PLoS5	Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Wrote the paper|Performed the movie	Performed the experiments	Performed the experiments	Investigation	YES
1940317	17712401	SL	PLoS5	Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Wrote the paper|Performed the movie	Analyzed the data	Analyzed the data	Formal analysis	YES
1940317	17712401	SL	PLoS5	Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Wrote the paper|Performed the movie	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1940317	17712401	SL	PLoS5	Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Wrote the paper|Performed the movie	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1940317	17712401	SL	PLoS5	Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Wrote the paper|Performed the movie	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1940317	17712401	SL	PLoS5	Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Wrote the paper|Performed the movie	Performed the movie	Performed the experiments	Investigation	YES
1940317	17712401	TR	PLoS5	Contributed reagents/materials/analysis tools|Revised the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1940317	17712401	TR	PLoS5	Contributed reagents/materials/analysis tools|Revised the paper	Revised the paper	Wrote the paper	Writing - Review & Editing	YES
5770358	29375614	CAL	7	Substantial contributions to the acquisition, analysis, and interpretation of data for the work; Revising the work critically for important intellectual content; Final approval of the version to be published; Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Substantial contributions to the acquisition, analysis, and interpretation of data for the work; Revising the work critically for important intellectual content; Final approval of the version to be published; Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Formal analysis|Investigation|Resources	YES
5770358	29375614	CEL	7	Substantial contributions to the conception and design of the work; Drafting the work and revising it critically for important intellectual content; Final approval of the version to be published; Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Substantial contributions to the conception and design of the work; Drafting the work and revising it critically for important intellectual content; Final approval of the version to be published; Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
5770358	29375614	CYL	7	Substantial contributions to the conception and design of the work; Drafting the work and revising it critically for important intellectual content; Final approval of the version to be published; Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Substantial contributions to the conception and design of the work; Drafting the work and revising it critically for important intellectual content; Final approval of the version to be published; Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
5770358	29375614	KF	7	Substantial contributions to the acquisition, analysis, and interpretation of data for the work; Revising the work critically for important intellectual content; Final approval of the version to be published; Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Substantial contributions to the acquisition, analysis, and interpretation of data for the work; Revising the work critically for important intellectual content; Final approval of the version to be published; Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Formal analysis|Investigation|Resources	YES
5770358	29375614	RZ	7	Substantial contributions to the acquisition, analysis, and interpretation of data for the work; Drafting the work and revising it critically for important intellectual content; Final approval of the version to be published; Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Substantial contributions to the acquisition, analysis, and interpretation of data for the work; Drafting the work and revising it critically for important intellectual content; Final approval of the version to be published; Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Data curation|Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5371579	28357784	AB	2	designed and conducted the experiments, evaluated the results and drafted the manuscript	designed and conducted the experiments, evaluated the results and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5371579	28357784	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5371579	28357784	KK	2	drafted the manuscript and helped in research design and data analysis	drafted the manuscript and helped in research design and data analysis	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5371579	28357784	PLH	2	helped in redox potential titrations, evaluated the redox potential titration results, and revised the manuscript	helped in redox potential titrations, evaluated the redox potential titration results, and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5371579	28357784	VBU	2	gave advices in the research work, helped in drafting the manuscript, and revised the manuscript	gave advices in the research work, helped in drafting the manuscript, and revised the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5688461	29143595	EG	2	drafted the manuscript|commented, revised/edited and approved the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5688461	29143595	EG	2	drafted the manuscript|commented, revised/edited and approved the manuscript	commented, revised/edited and approved the manuscript	Wrote the paper	Writing - Review & Editing	YES
5688461	29143595	GW	2	commented, revised/edited and approved the manuscript	commented, revised/edited and approved the manuscript	Wrote the paper	Writing - Review & Editing	YES
5688461	29143595	JB	2	commented, revised/edited and approved the manuscript	commented, revised/edited and approved the manuscript	Wrote the paper	Writing - Review & Editing	YES
5688461	29143595	VK	2	commented, revised/edited and approved the manuscript	commented, revised/edited and approved the manuscript	Wrote the paper	Writing - Review & Editing	YES
5688461	29143595	YP	2	drafted the manuscript|commented, revised/edited and approved the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5688461	29143595	YP	2	drafted the manuscript|commented, revised/edited and approved the manuscript	commented, revised/edited and approved the manuscript	Wrote the paper	Writing - Review & Editing	YES
4415951	25927529	HB	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415951	25927529	HB	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415951	25927529	KS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415951	25927529	KS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415951	25927529	KS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415951	25927529	KS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415951	25927529	MB	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415951	25927529	MB	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415951	25927529	ND	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415951	25927529	ND	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4884786	27234298	AB	2	analyzed fbxl17-sufu-gli1 levels in medulloblastoma	analyzed fbxl17-sufu-gli1 levels in medulloblastoma	Analyzed the data	Formal analysis	YES
4884786	27234298	All authors	2	discussed the results, commented on and assisted in revising the manuscript	discussed the results, commented on and assisted in revising the manuscript	Wrote the paper	Writing - Review & Editing	YES
4884786	27234298	CB	2	designed, performed, and analyzed the animal studies	designed, performed, and analyzed the animal studies	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
4884786	27234298	EF	2	helped with the biochemical studies	helped with the biochemical studies	Performed the experiments	Investigation	YES
4884786	27234298	FMB	2	analyzed fbxl17-sufu-gli1 levels in medulloblastoma	analyzed fbxl17-sufu-gli1 levels in medulloblastoma	Analyzed the data	Formal analysis	YES
4884786	27234298	JCC	2	provided expert advice on in vitro ubiquitylation experiments	provided expert advice on in vitro ubiquitylation experiments	Performed the experiments	Investigation	YES
4884786	27234298	LDM	2	performed the gcps study	performed the gcps study	Performed the experiments	Investigation	YES
4884786	27234298	MR	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4884786	27234298	MS	2	analysis of fbxl17-interacting proteins	analysis of fbxl17-interacting proteins	Performed the experiments	Investigation	YES
4884786	27234298	NRS	2	designed, performed, and analyzed the animal studies	designed, performed, and analyzed the animal studies	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
4884786	27234298	PI	2	performed the gcps study	performed the gcps study	Performed the experiments	Investigation	YES
4884786	27234298	SS	2	designed, performed, and analyzed the animal studies	designed, performed, and analyzed the animal studies	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
4884786	27234298	VDA	2	wrote the manuscript|coordinated the study and oversaw all experiments	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4884786	27234298	VDA	2	wrote the manuscript|coordinated the study and oversaw all experiments	coordinated the study and oversaw all experiments	-	Project administration|Supervision	YES
5470183	28630601	AAA	2	was responsible for drafting the manuscript and incorporating revisions suggested by his co-authors	was responsible for drafting the manuscript and incorporating revisions suggested by his co-authors	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5470183	28630601	All co-authors	2	were equally responsible for reviewing, editing, and providing feedback for submission of the final draft	were equally responsible for reviewing, editing, and providing feedback for submission of the final draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4415952	25928711	HWY	PLoS5	Participated in the design of this study|Revised manuscript	Participated in the design of this study	Conceived and designed the experiments	Methodology	YES
4415952	25928711	HWY	PLoS5	Participated in the design of this study|Revised manuscript	Revised manuscript	Wrote the paper	Writing - Review & Editing	YES
4415952	25928711	RHC	PLoS5	Participated in the design of this study|Revised manuscript	Participated in the design of this study	Conceived and designed the experiments	Methodology	YES
4415952	25928711	RHC	PLoS5	Participated in the design of this study|Revised manuscript	Revised manuscript	Wrote the paper	Writing - Review & Editing	YES
4415952	25928711	WWL	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415952	25928711	WWL	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415952	25928711	XC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415952	25928711	XC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415952	25928711	XC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415952	25928711	YL	PLoS5	Participated in the design of this study|Revised manuscript	Participated in the design of this study	Conceived and designed the experiments	Methodology	YES
4415952	25928711	YL	PLoS5	Participated in the design of this study|Revised manuscript	Revised manuscript	Wrote the paper	Writing - Review & Editing	YES
4415952	25928711	YX	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415952	25928711	ZC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Participated in the design of this study|Revised manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415952	25928711	ZC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Participated in the design of this study|Revised manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4415952	25928711	ZC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Participated in the design of this study|Revised manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4415952	25928711	ZC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Participated in the design of this study|Revised manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415952	25928711	ZC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Participated in the design of this study|Revised manuscript	Participated in the design of this study	Conceived and designed the experiments	Methodology	YES
4415952	25928711	ZC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Participated in the design of this study|Revised manuscript	Revised manuscript	Wrote the paper	Writing - Review & Editing	YES
1940318	17712428	RK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1940318	17712428	RK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1940318	17712428	RK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1940318	17712428	RK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1940318	17712428	RK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1940318	17712428	RL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1940318	17712428	RL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1940318	17712428	RL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1940318	17712428	TH	PLoS5	Analyzed the data|Provided background information on phosphonic acids in biological systems	Analyzed the data	Analyzed the data	Formal analysis	YES
1940318	17712428	TH	PLoS5	Analyzed the data|Provided background information on phosphonic acids in biological systems	Provided background information on phosphonic acids in biological systems	-	-	NO
1940318	17712428	TM	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1940318	17712428	TM	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5770366	29375615	GC	2	had the original idea|rootstock-mediated tolerance to biotic and abiotic stressors	had the original idea	Conceived and designed the experiments	Conceptualization	YES
5770366	29375615	GC	2	had the original idea|rootstock-mediated tolerance to biotic and abiotic stressors	rootstock-mediated tolerance to biotic and abiotic stressors	-	-	NO
5770366	29375615	K Confronting	2	the combinatorial effects of multiple stressors	the combinatorial effects of multiple stressors	-	-	NO
5770366	29375615	MK	2	had the original idea|contributed significantly to improve the final version of the article	had the original idea	Conceived and designed the experiments	Conceptualization	YES
5770366	29375615	MK	2	had the original idea|contributed significantly to improve the final version of the article	contributed significantly to improve the final version of the article	Wrote the paper	Writing - Review & Editing	YES
5770366	29375615	YR	2	had the original idea|rootstock-mediated tolerance to biotic and abiotic stressors|contributed significantly to improve the final version of the article	had the original idea	Conceived and designed the experiments	Conceptualization	YES
5770366	29375615	YR	2	had the original idea|rootstock-mediated tolerance to biotic and abiotic stressors|contributed significantly to improve the final version of the article	rootstock-mediated tolerance to biotic and abiotic stressors	-	-	NO
5770366	29375615	YR	2	had the original idea|rootstock-mediated tolerance to biotic and abiotic stressors|contributed significantly to improve the final version of the article	contributed significantly to improve the final version of the article	Wrote the paper	Writing - Review & Editing	YES
5770403	29375590	BW	PLoS52	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5770403	29375590	CD	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5770403	29375590	DJ	PLoS52	conceived and designed the experiments|revised the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5770403	29375590	DJ	PLoS52	conceived and designed the experiments|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5770403	29375590	EM	PLoS52	conceived and designed the experiments|analyzed data|wrote the manuscript|revised the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5770403	29375590	EM	PLoS52	conceived and designed the experiments|analyzed data|wrote the manuscript|revised the manuscript	analyzed data	Analyzed the data	Formal analysis	YES
5770403	29375590	EM	PLoS52	conceived and designed the experiments|analyzed data|wrote the manuscript|revised the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5770403	29375590	EM	PLoS52	conceived and designed the experiments|analyzed data|wrote the manuscript|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5770403	29375590	SM	PLoS52	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5770403	29375590	TN	PLoS52	collected the data|analyzed data|wrote the manuscript	collected the data	Performed the experiments	Investigation	YES
5770403	29375590	TN	PLoS52	collected the data|analyzed data|wrote the manuscript	analyzed data	Analyzed the data	Formal analysis	YES
5770403	29375590	TN	PLoS52	collected the data|analyzed data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5770403	29375590	YT	PLoS52	analyzed data|wrote the manuscript	analyzed data	Analyzed the data	Formal analysis	YES
5770403	29375590	YT	PLoS52	analyzed data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5688471	29143597	AL	2	obtained patient data, analysed and interpreted the patient data and wrote the manuscript	obtained patient data, analysed and interpreted the patient data and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5688471	29143597	ALA	2	were in charge of data collection and analysis	were in charge of data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5688471	29143597	AS	2	obtained patient data, analysed and interpreted the patient data and wrote the manuscript	obtained patient data, analysed and interpreted the patient data and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5688471	29143597	GN-G	2	obtained patient data, analysed and interpreted the patient data and wrote the manuscript	obtained patient data, analysed and interpreted the patient data and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5688471	29143597	GP-M	2	were in charge of data collection and analysis	were in charge of data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5688471	29143597	HP-G	2	were in charge of data collection and analysis	were in charge of data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5688471	29143597	JA	2	were in charge of data collection and analysis	were in charge of data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5688471	29143597	JC-C	2	were in charge of data collection and analysis	were in charge of data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5688471	29143597	MP	2	were in charge of data collection and analysis	were in charge of data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5688471	29143597	TP	2	were in charge of data collection and analysis	were in charge of data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5378567	28374344	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5378567	28374344	CL	2	designed the work, performed the research study and drafted the manuscript	designed the work, performed the research study and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5378567	28374344	QS	2	designed and supervised the research study	designed and supervised the research study	Conceived and designed the experiments	Methodology|Supervision	YES
5378567	28374344	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5378567	28374344	WMP	2	designed the work, performed the research study and drafted the manuscript	designed the work, performed the research study and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5378567	28374344	WXJ	2	guided and participated in collection of algae samples	guided and participated in collection of algae samples	Performed the experiments	Investigation|Supervision	YES
5378567	28374344	YPS	2	designed and supervised the research study	designed and supervised the research study	Conceived and designed the experiments	Methodology|Supervision	YES
5378567	28374344	ZZJ	2	was involved in critically revision the manuscript	was involved in critically revision the manuscript	Wrote the paper	Writing - Review & Editing	YES
4969571	27334615	AH	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
4969571	27334615	AJG	2	performed experiments|designed experiments|edited the manuscript	performed experiments	Performed the experiments	Investigation	YES
4969571	27334615	AJG	2	performed experiments|designed experiments|edited the manuscript	designed experiments	Conceived and designed the experiments	Methodology	YES
4969571	27334615	AJG	2	performed experiments|designed experiments|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
4969571	27334615	AJW	2	edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
4969571	27334615	AM	2	performed experiments|wrote the manuscript	performed experiments	Performed the experiments	Investigation	YES
4969571	27334615	AM	2	performed experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4969571	27334615	BKK	2	provided reagents|edited the manuscript	provided reagents	Contributed reagents/materials/analysis tools	Resources	YES
4969571	27334615	BKK	2	provided reagents|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
4969571	27334615	CPW	2	performed experiments|wrote the manuscript	performed experiments	Performed the experiments	Investigation	YES
4969571	27334615	CPW	2	performed experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4969571	27334615	CSB	2	performed experiments|wrote the manuscript	performed experiments	Performed the experiments	Investigation	YES
4969571	27334615	CSB	2	performed experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4969571	27334615	EFS	2	performed experiments|wrote the manuscript	performed experiments	Performed the experiments	Investigation	YES
4969571	27334615	EFS	2	performed experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4969571	27334615	GMH	2	performed experiments|edited the manuscript	performed experiments	Performed the experiments	Investigation	YES
4969571	27334615	GMH	2	performed experiments|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
4969571	27334615	KJDV	2	performed experiments|designed experiments|wrote the manuscript|supervised the research	performed experiments	Performed the experiments	Investigation	YES
4969571	27334615	KJDV	2	performed experiments|designed experiments|wrote the manuscript|supervised the research	designed experiments	Conceived and designed the experiments	Methodology	YES
4969571	27334615	KJDV	2	performed experiments|designed experiments|wrote the manuscript|supervised the research	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4969571	27334615	KJDV	2	performed experiments|designed experiments|wrote the manuscript|supervised the research	supervised the research	-	Supervision	YES
4969571	27334615	KM	2	provided reagents|edited the manuscript	provided reagents	Contributed reagents/materials/analysis tools	Resources	YES
4969571	27334615	KM	2	provided reagents|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
4969571	27334615	LF	2	performed experiments|wrote the manuscript	performed experiments	Performed the experiments	Investigation	YES
4969571	27334615	LF	2	performed experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4969571	27334615	MJW	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
4969571	27334615	MM	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
4969571	27334615	PJS	2	provided reagents|edited the manuscript	provided reagents	Contributed reagents/materials/analysis tools	Resources	YES
4969571	27334615	PJS	2	provided reagents|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
4415953	25928811	FDG	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415953	25928811	FDG	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415953	25928811	FDG	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415953	25928811	FDG	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415953	25928811	JET	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Supervision or mentorship	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415953	25928811	JET	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Supervision or mentorship	Analyzed the data	Analyzed the data	Formal analysis	YES
4415953	25928811	JET	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Supervision or mentorship	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415953	25928811	JET	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Supervision or mentorship	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415953	25928811	JET	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Supervision or mentorship	Supervision or mentorship	-	Supervision	YES
1940319	17712417	BW	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1940319	17712417	BW	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1940319	17712417	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1940319	17712417	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1940319	17712417	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1940319	17712417	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1940319	17712417	JR	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1940319	17712417	KW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1940319	17712417	LT	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1940319	17712417	MS	PLoS5	Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1940319	17712417	MS	PLoS5	Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1940319	17712417	PM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1940319	17712417	PM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1940319	17712417	RW	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1940319	17712417	SD	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1940319	17712417	SD	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1940319	17712417	VJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1940319	17712417	VJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1940319	17712417	VJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1940319	17712417	VJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4621332	26550577	Christina Routsi	2	have substantially contributed to the revision and editing of the draft	have substantially contributed to the revision and editing of the draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4621332	26550577	Dimitris Goukos	2	have assembled and interpreted the data and run the experiments	have assembled and interpreted the data and run the experiments	Analyzed the data	Formal analysis	YES
4621332	26550577	Efrossini Briassouli	2	has generated, collected, and analyzed the data|have assembled and interpreted the data and run the experiments|drafted the paper	has generated, collected, and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4621332	26550577	Efrossini Briassouli	2	has generated, collected, and analyzed the data|have assembled and interpreted the data and run the experiments|drafted the paper	have assembled and interpreted the data and run the experiments	Analyzed the data	Formal analysis	YES
4621332	26550577	Efrossini Briassouli	2	has generated, collected, and analyzed the data|have assembled and interpreted the data and run the experiments|drafted the paper	drafted the paper	Wrote the paper	Writing - Original Draft	YES
4621332	26550577	George Briassoulis	2	have conceived and designed the study|drafted the paper	have conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4621332	26550577	George Briassoulis	2	have conceived and designed the study|drafted the paper	drafted the paper	Wrote the paper	Writing - Original Draft	YES
4621332	26550577	George Daikos	2	have conceived and designed the study|has finally approved the submitted version	have conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4621332	26550577	George Daikos	2	have conceived and designed the study|has finally approved the submitted version	has finally approved the submitted version	-	-	NO
4621332	26550577	Kleovoulos Apostolou	2	have substantially contributed to acquisition and record of data	have substantially contributed to acquisition and record of data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4621332	26550577	Kostas Vardas	2	have substantially contributed to acquisition and record of data	have substantially contributed to acquisition and record of data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4621332	26550577	Marianna Tzanoudaki	2	have assembled and interpreted the data and run the experiments	have assembled and interpreted the data and run the experiments	Analyzed the data	Formal analysis	YES
4621332	26550577	Serafim Nanas	2	have substantially contributed to the revision and editing of the draft	have substantially contributed to the revision and editing of the draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4621332	26550577	all authors	2	edited and approved the final version of the paper	edited and approved the final version of the paper	Wrote the paper	Writing - Review & Editing	YES
3867955	24381526	Caixia Wang Xiangnan	2	contributed equally to this work	contributed equally to this work	-	-	NO
5380569	28378284	All	2	animal experiment procedures were conducted in accordance with the guidelines of the animal welfare act and all procedures and protocols were approved by the institutional animal care and use committee of the sichuan agricultural university	animal experiment procedures were conducted in accordance with the guidelines of the animal welfare act and all procedures and protocols were approved by the institutional animal care and use committee of the sichuan agricultural university	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5380569	28378284	All authors	2	contributed to the design of the experiment|read and approved the final manuscript	contributed to the design of the experiment	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5380569	28378284	All authors	2	contributed to the design of the experiment|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5380569	28378284	PJ	2	analyzed the experimental data	analyzed the experimental data	Analyzed the data	Formal analysis	YES
5380569	28378284	SX	2	analyzed the experimental data	analyzed the experimental data	Analyzed the data	Formal analysis	YES
5380569	28378284	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5380569	28378284	YZ	2	performed and wrote the experiments	performed and wrote the experiments	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4969574	27288401	AF	2	conceived and designed experiments, and wrote the paper	conceived and designed experiments, and wrote the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
4969574	27288401	DAJ	2	conceived and designed experiments, and wrote the paper	conceived and designed experiments, and wrote the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
4969574	27288401	EM	2	conducted experiments	conducted experiments	Performed the experiments	Investigation	YES
4969574	27288401	OS	2	conceived and designed experiments, and wrote the paper|conducted experiments	conceived and designed experiments, and wrote the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
4969574	27288401	OS	2	conceived and designed experiments, and wrote the paper|conducted experiments	conducted experiments	Performed the experiments	Investigation	YES
4969574	27288401	PSF	2	conceived and designed experiments, and wrote the paper	conceived and designed experiments, and wrote the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
4969574	27288401	SP	2	conceived and designed experiments, and wrote the paper|conducted experiments	conceived and designed experiments, and wrote the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
4969574	27288401	SP	2	conceived and designed experiments, and wrote the paper|conducted experiments	conducted experiments	Performed the experiments	Investigation	YES
5688475	29143670	CW	2	was the primary author	was the primary author	Wrote the paper	Writing - Original Draft	YES
5688475	29143670	JC	2	provided expert advice and edits to the manuscript	provided expert advice and edits to the manuscript	Wrote the paper	Writing - Review & Editing	YES
5688475	29143670	JL	2	provided expert advice and edits to the manuscript	provided expert advice and edits to the manuscript	Wrote the paper	Writing - Review & Editing	YES
5688475	29143670	KA	2	provided expert advice and edits to the manuscript	provided expert advice and edits to the manuscript	Wrote the paper	Writing - Review & Editing	YES
5688475	29143670	MW	2	checked the nomenclature of all variants and terminology used	checked the nomenclature of all variants and terminology used	-	-	NO
5688475	29143670	NE	2	provided expert advice and edits to the manuscript	provided expert advice and edits to the manuscript	Wrote the paper	Writing - Review & Editing	YES
5688475	29143670	UW	2	provided expert advice and edits to the manuscript	provided expert advice and edits to the manuscript	Wrote the paper	Writing - Review & Editing	YES
5770615	29375587	All authors	2	helped drafting the manuscript and gave essential input to the work	helped drafting the manuscript and gave essential input to the work	Wrote the paper	Writing - Original Draft	YES
5770615	29375587	HC	2	conducted the experiment	conducted the experiment	Performed the experiments	Investigation	YES
5770615	29375587	J-YM	2	conceived and designed the experiment	conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5770615	29375587	SZ	2	conceived and designed the experiment|conducted the experiment|analyzed data|wrote the manuscript	conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5770615	29375587	SZ	2	conceived and designed the experiment|conducted the experiment|analyzed data|wrote the manuscript	conducted the experiment	Performed the experiments	Investigation	YES
5770615	29375587	SZ	2	conceived and designed the experiment|conducted the experiment|analyzed data|wrote the manuscript	analyzed data	Analyzed the data	Formal analysis	YES
5770615	29375587	SZ	2	conceived and designed the experiment|conducted the experiment|analyzed data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5770615	29375587	WS	2	conceived and designed the experiment|analyzed data|wrote the manuscript	conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5770615	29375587	WS	2	conceived and designed the experiment|analyzed data|wrote the manuscript	analyzed data	Analyzed the data	Formal analysis	YES
5770615	29375587	WS	2	conceived and designed the experiment|analyzed data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5770615	29375587	YL	2	conceived and designed the experiment	conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5770615	29375587	YX	2	conducted the experiment	conducted the experiment	Performed the experiments	Investigation	YES
5477153	28642676	All	2	other coauthors reviewed, edited, and approved the draft, and the final manuscript	other coauthors reviewed, edited, and approved the draft, and the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5477153	28642676	BIC	2	prepared and compiled the draft for review and editing by coauthors	prepared and compiled the draft for review and editing by coauthors	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5477153	28642676	CMK	2	prepared and compiled the draft for review and editing by coauthors	prepared and compiled the draft for review and editing by coauthors	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5477153	28642676	PJC	2	prepared and compiled the draft for review and editing by coauthors	prepared and compiled the draft for review and editing by coauthors	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5477153	28642676	RJ	2	prepared and compiled the draft for review and editing by coauthors	prepared and compiled the draft for review and editing by coauthors	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5477153	28642676	SDW	2	prepared and compiled the draft for review and editing by coauthors	prepared and compiled the draft for review and editing by coauthors	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5738642	29241406	AB	2	gave elaborative information concerning the russian system	gave elaborative information concerning the russian system	-	-	NO
5738642	29241406	GR	2	collected the data|gave elaborative information concerning the russian system	collected the data	Performed the experiments	Investigation	YES
5738642	29241406	GR	2	collected the data|gave elaborative information concerning the russian system	gave elaborative information concerning the russian system	-	-	NO
5738642	29241406	HMD	2	collected the data|conducted the data analysis	collected the data	Performed the experiments	Investigation	YES
5738642	29241406	HMD	2	collected the data|conducted the data analysis	conducted the data analysis	Analyzed the data	Formal analysis	YES
5738642	29241406	TO	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5738642	29241406	all authors	2	were involved in writing the manuscript|read and approved the final manuscript	were involved in writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5738642	29241406	all authors	2	were involved in writing the manuscript|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4415954	25928815	GQL	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415954	25928815	HX	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4415954	25928815	SB	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4415954	25928815	SB	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415954	25928815	SZB	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4415954	25928815	YY	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415954	25928815	YY	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415954	25928815	ZT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415954	25928815	ZT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415954	25928815	ZT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415954	25928815	ZT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415954	25928815	ZT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415954	25928815	ZWY	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4415954	25928815	ZXY	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1940320	17712429	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1940320	17712429	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1940320	17712429	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1940320	17712429	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1940320	17712429	PM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1940320	17712429	PM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1940320	17712429	TC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5688477	29143599	A. Acquisition	2	of data	of data	-	-	NO
5688477	29143599	All authors	2	were involved in drafting the article or revising it critically for important intellectual content, and all authors approved the final version to be published	were involved in drafting the article or revising it critically for important intellectual content, and all authors approved the final version to be published	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5688477	29143599	Hirose N. Analysis	2	interpretation of data	interpretation of data	Analyzed the data	Formal analysis	YES
5688477	29143599	MH	2	interpretation of data	interpretation of data	Analyzed the data	Formal analysis	YES
5688477	29143599	MM	2	interpretation of data	interpretation of data	Analyzed the data	Formal analysis	YES
4415955	25927838	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415955	25927838	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415955	25927838	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415955	25927838	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415955	25927838	EPM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415955	25927838	EPM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415955	25927838	EPM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415955	25927838	EPM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415955	25927838	MMG	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415955	25927838	MMG	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4969576	27357570	AR	2	designed the experiments and analyzed the data|performed most of the experiments	designed the experiments and analyzed the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
4969576	27357570	AR	2	designed the experiments and analyzed the data|performed most of the experiments	performed most of the experiments	Performed the experiments	Investigation	YES
4969576	27357570	All authors	2	discussed the results	discussed the results	-	-	NO
4969576	27357570	GM	2	designed the experiments and analyzed the data|performed most of the experiments	designed the experiments and analyzed the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
4969576	27357570	GM	2	designed the experiments and analyzed the data|performed most of the experiments	performed most of the experiments	Performed the experiments	Investigation	YES
4969576	27357570	LB	2	performed the frap and photoconversion experiments	performed the frap and photoconversion experiments	Performed the experiments	Investigation	YES
4969576	27357570	PC	2	conceived and supervised the project|designed the experiments and analyzed the data	conceived and supervised the project	Conceived and designed the experiments	Conceptualization|Supervision	YES
4969576	27357570	PC	2	conceived and supervised the project|designed the experiments and analyzed the data	designed the experiments and analyzed the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5496333	28680370	AM	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5496333	28680370	AM	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5496333	28680370	DE	PLoS52	performed the experiments|performed the experiments|analyzed the data|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5496333	28680370	DE	PLoS52	performed the experiments|performed the experiments|analyzed the data|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5496333	28680370	DE	PLoS52	performed the experiments|performed the experiments|analyzed the data|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5496333	28680370	DE	PLoS52	performed the experiments|performed the experiments|analyzed the data|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5496333	28680370	GO	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5496333	28680370	GO	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5496333	28680370	KB	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5496333	28680370	KB	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5496333	28680370	LG	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5496333	28680370	LG	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5496333	28680370	NM	PLoS52	performed the experiments|performed the experiments|analyzed the data|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5496333	28680370	NM	PLoS52	performed the experiments|performed the experiments|analyzed the data|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5496333	28680370	NM	PLoS52	performed the experiments|performed the experiments|analyzed the data|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5496333	28680370	NM	PLoS52	performed the experiments|performed the experiments|analyzed the data|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5496333	28680370	PJA	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the manuscript|commented on the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5496333	28680370	PJA	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the manuscript|commented on the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5496333	28680370	PJA	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the manuscript|commented on the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5496333	28680370	PJA	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the manuscript|commented on the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5496333	28680370	PJA	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the manuscript|commented on the manuscript	commented on the manuscript	-	-	NO
5496333	28680370	SB	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5496333	28680370	SB	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5496333	28680370	SC	PLoS52	conceived and designed the experiments|commented on the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5496333	28680370	SC	PLoS52	conceived and designed the experiments|commented on the manuscript	commented on the manuscript	-	-	NO
5496333	28680370	SJI	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the manuscript|commented on the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5496333	28680370	SJI	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the manuscript|commented on the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5496333	28680370	SJI	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the manuscript|commented on the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5496333	28680370	SJI	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the manuscript|commented on the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5496333	28680370	SJI	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the manuscript|commented on the manuscript	commented on the manuscript	-	-	NO
5496333	28680370	YR	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5496333	28680370	YR	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
4621339	26550565	Fei Wang	2	contributed equally to this study	contributed equally to this study	-	-	NO
4621339	26550565	Xiao-Xia Su	2	contributed equally to this study	contributed equally to this study	-	-	NO
5380647	28378285	All authors	2	read and approved the finial manuscript	read and approved the finial manuscript	-	-	NO
5380647	28378285	CJC	2	helped lhl collect ruminal fluid	helped lhl collect ruminal fluid	-	-	NO
5380647	28378285	HXC	2	helped lhl measure the number of bacteria in the culture	helped lhl measure the number of bacteria in the culture	Performed the experiments	Investigation	YES
5380647	28378285	JHY	2	gave advices for the experiment design and for the discussion of the manuscript	gave advices for the experiment design and for the discussion of the manuscript	Conceived and designed the experiments	Methodology	YES
5380647	28378285	LHL	2	is the main performer of this experiment|designed the experiment and wrote the manuscript|to measure the vfa and nh4-n in the culture	is the main performer of this experiment	Performed the experiments	Investigation	YES
5380647	28378285	LHL	2	is the main performer of this experiment|designed the experiment and wrote the manuscript|to measure the vfa and nh4-n in the culture	designed the experiment and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5380647	28378285	LHL	2	is the main performer of this experiment|designed the experiment and wrote the manuscript|to measure the vfa and nh4-n in the culture	to measure the vfa and nh4-n in the culture	Performed the experiments	Investigation	YES
5380647	28378285	XRX	2	designed the experiment and wrote the manuscript	designed the experiment and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
1940323	17712418	AT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1940323	17712418	AT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1940323	17712418	AT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1940323	17712418	AV	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1940323	17712418	CM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1940323	17712418	DB	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1940323	17712418	DW	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1940323	17712418	DW	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1940323	17712418	JR	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1940323	17712418	JR	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1940323	17712418	LK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1940323	17712418	ME	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1940323	17712418	ME	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1940323	17712418	PK	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1940323	17712418	PK	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1940323	17712418	RA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1940323	17712418	RA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1940323	17712418	RA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1940323	17712418	RA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1940323	17712418	TB	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1940323	17712418	TB	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1940323	17712418	WP	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5770625	29375588	All authors	2	listed have made a substantial, direct and intellectual contribution to the work, and approved it for publication	listed have made a substantial, direct and intellectual contribution to the work, and approved it for publication	-	-	NO
4415971	25927235	HS	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4415971	25927235	IMS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415971	25927235	IMS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415971	25927235	IMS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415971	25927235	IMS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415971	25927235	IMS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415971	25927235	MD	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415971	25927235	MD	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415971	25927235	MD	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415971	25927235	NH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415971	25927235	NH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4415971	25927235	NH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5688488	29143593	AL	2	provided expert advice and edits to the manuscript	provided expert advice and edits to the manuscript	Wrote the paper	Writing - Review & Editing	YES
5688488	29143593	GW	2	provided expert advice and edits to the manuscript	provided expert advice and edits to the manuscript	Wrote the paper	Writing - Review & Editing	YES
5688488	29143593	NE	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5688488	29143593	SV	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5688488	29143593	YP	2	provided expert advice and edits to the manuscript	provided expert advice and edits to the manuscript	Wrote the paper	Writing - Review & Editing	YES
5506682	28706467	CZ	4	The study was designed by|data were collected and analysed by|data interpretation and manuscript preparation were undertaken by	The study was designed by	Conceived and designed the experiments	Methodology	YES
5506682	28706467	CZ	4	The study was designed by|data were collected and analysed by|data interpretation and manuscript preparation were undertaken by	data were collected and analysed by	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5506682	28706467	CZ	4	The study was designed by|data were collected and analysed by|data interpretation and manuscript preparation were undertaken by	data interpretation and manuscript preparation were undertaken by	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5506682	28706467	EM	4	data were collected and analysed by	data were collected and analysed by	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5506682	28706467	MW	4	data were collected and analysed by|data interpretation and manuscript preparation were undertaken by	data were collected and analysed by	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5506682	28706467	MW	4	data were collected and analysed by|data interpretation and manuscript preparation were undertaken by	data interpretation and manuscript preparation were undertaken by	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5506682	28706467	MaW	4	The study was designed by|data were collected and analysed by|data interpretation and manuscript preparation were undertaken by	The study was designed by	Conceived and designed the experiments	Methodology	YES
5506682	28706467	MaW	4	The study was designed by|data were collected and analysed by|data interpretation and manuscript preparation were undertaken by	data were collected and analysed by	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5506682	28706467	MaW	4	The study was designed by|data were collected and analysed by|data interpretation and manuscript preparation were undertaken by	data interpretation and manuscript preparation were undertaken by	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5506682	28706467	SC	4	data interpretation and manuscript preparation were undertaken by	data interpretation and manuscript preparation were undertaken by	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4972137	26873592	ASc	2	conducted the electrophysiological studies	conducted the electrophysiological studies	Performed the experiments	Investigation	YES
4972137	26873592	ASu	2	purified the proteins, produced and screened the crystals|undertook the crystallographic data collection, structure solution and refinements|analysed the structures	purified the proteins, produced and screened the crystals	Performed the experiments	Investigation	YES
4972137	26873592	ASu	2	purified the proteins, produced and screened the crystals|undertook the crystallographic data collection, structure solution and refinements|analysed the structures	undertook the crystallographic data collection, structure solution and refinements	Performed the experiments	Investigation	YES
4972137	26873592	ASu	2	purified the proteins, produced and screened the crystals|undertook the crystallographic data collection, structure solution and refinements|analysed the structures	analysed the structures	-	-	NO
4972137	26873592	BAW	2	analysed the structures|wrote the initial draft of the manuscript, which was discussed, modified and approved by all authors|supervised the project	analysed the structures	-	-	NO
4972137	26873592	BAW	2	analysed the structures|wrote the initial draft of the manuscript, which was discussed, modified and approved by all authors|supervised the project	wrote the initial draft of the manuscript, which was discussed, modified and approved by all authors	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4972137	26873592	BAW	2	analysed the structures|wrote the initial draft of the manuscript, which was discussed, modified and approved by all authors|supervised the project	supervised the project	-	Supervision	YES
4972137	26873592	CB	2	undertook the crystallographic data collection, structure solution and refinements|analysed the structures	undertook the crystallographic data collection, structure solution and refinements	Performed the experiments	Investigation	YES
4972137	26873592	CB	2	undertook the crystallographic data collection, structure solution and refinements|analysed the structures	analysed the structures	-	-	NO
4972137	26873592	CEN	2	undertook the crystallographic data collection, structure solution and refinements|performed the electrostatic calculations|analysed the structures	undertook the crystallographic data collection, structure solution and refinements	Performed the experiments	Investigation	YES
4972137	26873592	CEN	2	undertook the crystallographic data collection, structure solution and refinements|performed the electrostatic calculations|analysed the structures	performed the electrostatic calculations	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4972137	26873592	CEN	2	undertook the crystallographic data collection, structure solution and refinements|performed the electrostatic calculations|analysed the structures	analysed the structures	-	-	NO
4972137	26873592	DEC	2	analysed the electrophysiology results|supervised the project	analysed the electrophysiology results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4972137	26873592	DEC	2	analysed the electrophysiology results|supervised the project	supervised the project	-	Supervision	YES
4972137	26873592	PGD	2	analysed the electrophysiology results	analysed the electrophysiology results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
1940324	17710137	OR	PLoS5	Wrote the paper|Developed software|Tested software	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1940324	17710137	OR	PLoS5	Wrote the paper|Developed software|Tested software	Developed software	Contributed reagents/materials/analysis tools	Software	YES
1940324	17710137	OR	PLoS5	Wrote the paper|Developed software|Tested software	Tested software	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
1940324	17710137	RD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Tested software	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1940324	17710137	RD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Tested software	Performed the experiments	Performed the experiments	Investigation	YES
1940324	17710137	RD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Tested software	Analyzed the data	Analyzed the data	Formal analysis	YES
1940324	17710137	RD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Tested software	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1940324	17710137	RD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Tested software	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1940324	17710137	RD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Tested software	Tested software	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
1940324	17710137	RD-U	PLoS5	Developed software	Developed software	Contributed reagents/materials/analysis tools	Software	YES
4415972	25928376	AD	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415972	25928376	BDK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4415972	25928376	CL	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415972	25928376	CL	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4415972	25928376	HJ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4415972	25928376	KCW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415972	25928376	KCW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415972	25928376	KCW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415972	25928376	KCW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415972	25928376	MRM	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4415972	25928376	MRM	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4415972	25928376	MTM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4415972	25928376	PTV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415972	25928376	PTV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4415972	25928376	PTV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4415972	25928376	SGS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415972	25928376	SGS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415972	25928376	SGS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415972	25928376	WLK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415972	25928376	WLK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415972	25928376	WLK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5508798	28717347	EO	2	conceived the study|participated in the design and coordination of the study|helped to draft the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5508798	28717347	EO	2	conceived the study|participated in the design and coordination of the study|helped to draft the manuscript	participated in the design and coordination of the study	Conceived and designed the experiments	Methodology|Project administration	YES
5508798	28717347	EO	2	conceived the study|participated in the design and coordination of the study|helped to draft the manuscript	helped to draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5508798	28717347	KY	2	conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5508798	28717347	YT	2	participated in the design and coordination of the study|carried out the data collection and performed the statistical analysis|helped to draft the manuscript	participated in the design and coordination of the study	Conceived and designed the experiments	Methodology|Project administration	YES
5508798	28717347	YT	2	participated in the design and coordination of the study|carried out the data collection and performed the statistical analysis|helped to draft the manuscript	carried out the data collection and performed the statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5508798	28717347	YT	2	participated in the design and coordination of the study|carried out the data collection and performed the statistical analysis|helped to draft the manuscript	helped to draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5383910	28389899	AS	2	performed experiments, conceived of the study, designed experiments, analysed the data, and wrote the manuscript	performed experiments, conceived of the study, designed experiments, analysed the data, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5383910	28389899	Both authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5383910	28389899	YI	2	made a substantial contribution to the analysis and interpretation of the data presented	made a substantial contribution to the analysis and interpretation of the data presented	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5688489	29143608	DC	2	was involved in the manuscript conception, design and critical revision	was involved in the manuscript conception, design and critical revision	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5688489	29143608	EG	2	were involved in the conception and design of the review, literature collection and interpretation, manuscript preparation	were involved in the conception and design of the review, literature collection and interpretation, manuscript preparation	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5688489	29143608	GW	2	were involved in the manuscript preparation and critical revision of the manuscript	were involved in the manuscript preparation and critical revision of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5688489	29143608	ID	2	were involved in the conception and design of the review, literature collection and interpretation, manuscript preparation	were involved in the conception and design of the review, literature collection and interpretation, manuscript preparation	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5688489	29143608	LDL	2	were involved in the critical revision of the manuscript	were involved in the critical revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5688489	29143608	NM	2	were involved in the manuscript preparation and critical revision of the manuscript	were involved in the manuscript preparation and critical revision of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5688489	29143608	YP	2	were involved in the critical revision of the manuscript	were involved in the critical revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4415973	25928879	AS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415973	25928879	AS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415973	25928879	AS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415973	25928879	AS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415973	25928879	DF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415973	25928879	DF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415973	25928879	DF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415973	25928879	DF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415973	25928879	DF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415973	25928879	JB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415973	25928879	JB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415973	25928879	JB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415973	25928879	JB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415973	25928879	JDW	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4415973	25928879	JDW	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415973	25928879	JM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4415973	25928879	JN	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4415973	25928879	UF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415973	25928879	UF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415973	25928879	UF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415973	25928879	UF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415973	25928879	UF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1940325	17710128	CL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1940325	17710128	CL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1940325	17710128	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1940325	17710128	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1940325	17710128	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1940325	17710128	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1940325	17710128	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1940325	17710128	JK	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1940325	17710128	JK	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1940325	17710128	SE	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1940325	17710128	SE	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1940325	17710128	SE	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1940325	17710128	SE	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1940325	17710128	TS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1940325	17710128	TS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1940325	17710128	TS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1940325	17710128	TS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1940325	17710128	TS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1940325	17710128	VI	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1940325	17710128	VI	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5770637	29375589	All authors	2	contributed to the field and lab work, the analysis and interpretation of data, and the writing of the manuscript|approved the final version of the manuscript	contributed to the field and lab work, the analysis and interpretation of data, and the writing of the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft	YES
5770637	29375589	All authors	2	contributed to the field and lab work, the analysis and interpretation of data, and the writing of the manuscript|approved the final version of the manuscript	approved the final version of the manuscript	-	-	NO
5770637	29375589	GvO	2	conceived of the study	conceived of the study	Conceived and designed the experiments	Conceptualization	YES
5770637	29375589	UF	2	conceived of the study	conceived of the study	Conceived and designed the experiments	Conceptualization	YES
5770637	29375589	WH	2	conceived of the study	conceived of the study	Conceived and designed the experiments	Conceptualization	YES
5007552	27481935	DC	2	helped with design of experiments and analysis of data	helped with design of experiments and analysis of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5007552	27481935	DRA	2	conceived of the project, helped with experimental design and analysis and interpretation of data and played a major role in preparation of the manuscript	conceived of the project, helped with experimental design and analysis and interpretation of data and played a major role in preparation of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5007552	27481935	ES	2	designed, executed experiments and analysed data	designed, executed experiments and analysed data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5007552	27481935	JB	2	helped with design of experiments and analysis of data	helped with design of experiments and analysis of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5007552	27481935	NS	2	synthetised sgk inhibitors used in this study	synthetised sgk inhibitors used in this study	-	-	NO
5007552	27481935	PAE	2	helped with design of experiments, analysis of the data and helped with the preparation of the manuscript	helped with design of experiments, analysis of the data and helped with the preparation of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5007552	27481935	PC	2	designed, executed experiments, analysed data and helped with preparation of the manuscript	designed, executed experiments, analysed data and helped with preparation of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5521097	28736511	DH	2	led the statistical analysis and contributed to interpretation of results and drafting of the manuscript	led the statistical analysis and contributed to interpretation of results and drafting of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5521097	28736511	DT	2	contributed to experimental implementation, interpretation of results, and drafting of the manuscript	contributed to experimental implementation, interpretation of results, and drafting of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5521097	28736511	EW	2	developed the objectives of the study and intervention, contributed to experimental design and implementation, managed data collection and processing, contributed to statistical analysis and interpretation of results, and lead the drafting of the manuscript	developed the objectives of the study and intervention, contributed to experimental design and implementation, managed data collection and processing, contributed to statistical analysis and interpretation of results, and lead the drafting of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Data curation|Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
5521097	28736511	HZ	2	oversaw the research team and provided mentorship for conducting clinical trials	oversaw the research team and provided mentorship for conducting clinical trials	Performed the experiments	Investigation|Supervision	YES
5521097	28736511	KT	2	contributed to experimental design and implementation, data collection, interpretation of the results, and drafting of the manuscript	contributed to experimental design and implementation, data collection, interpretation of the results, and drafting of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
5521097	28736511	RD	2	contributed to experimental design and implementation, data collection, and drafting of the manuscript	contributed to experimental design and implementation, data collection, and drafting of the manuscript	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Methodology|Resources|Writing - Original Draft	YES
5688492	29143655	All authors	2	participated in drafting all aspects of the manuscript	participated in drafting all aspects of the manuscript	Wrote the paper	Writing - Original Draft	YES
4415974	25927705	MWM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415974	25927705	MWM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415974	25927705	MWM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415974	25927705	MWM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415974	25927705	MWM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415975	25928423	JM	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415975	25928423	JM	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415975	25928423	KP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4415975	25928423	KZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Obtained permission for use of cell line	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415975	25928423	KZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Obtained permission for use of cell line	Performed the experiments	Performed the experiments	Investigation	YES
4415975	25928423	KZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Obtained permission for use of cell line	Analyzed the data	Analyzed the data	Formal analysis	YES
4415975	25928423	KZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Obtained permission for use of cell line	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415975	25928423	KZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Obtained permission for use of cell line	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415975	25928423	KZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Obtained permission for use of cell line	Obtained permission for use of cell line	Performed the experiments	Investigation	YES
4415975	25928423	MK	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4415975	25928423	MK	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415975	25928423	MW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415975	25928423	MW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415975	25928423	MW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415975	25928423	MW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415975	25928423	MW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415975	25928423	RL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415975	25928423	RL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415975	25928423	WL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4415975	25928423	WL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4415975	25928423	WL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4415975	25928423	WL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1940326	17710125	AH	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1940326	17710125	AH	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1940326	17710125	EO	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1940326	17710125	GF	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1940326	17710125	KM	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1940326	17710125	NP	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1940326	17710125	NP	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1940326	17710125	PB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Enrolled patients	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1940326	17710125	PB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Enrolled patients	Analyzed the data	Analyzed the data	Formal analysis	YES
1940326	17710125	PB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Enrolled patients	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1940326	17710125	PB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Enrolled patients	Enrolled patients	Performed the experiments	Investigation	YES
1940326	17710125	PM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1940326	17710125	PM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1940326	17710125	PM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1940326	17710125	SG	PLoS5	Performed the experiments|Supplied and provided quality assurance of vaccines used in clinical trial	Performed the experiments	Performed the experiments	Investigation	YES
1940326	17710125	SG	PLoS5	Performed the experiments|Supplied and provided quality assurance of vaccines used in clinical trial	Supplied and provided quality assurance of vaccines used in clinical trial	Performed the experiments|Contributed reagents/materials/analysis tools	Resources|Validation	YES
1940326	17710125	TL	PLoS5	Conceived and designed the experiments|Support	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1940326	17710125	TL	PLoS5	Conceived and designed the experiments|Support	Support	-	-	NO
1940326	17710125	TM	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1940326	17710125	TM	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5385187	28391484	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5385187	28391484	DD	2	helped to draft manuscript and gave some interpretation on data	helped to draft manuscript and gave some interpretation on data	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5385187	28391484	EE	2	participated in the design of the study and carried out the molecular studies, genome sequencing, and sequencing data analysis as well as drafted manuscript	participated in the design of the study and carried out the molecular studies, genome sequencing, and sequencing data analysis as well as drafted manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5385187	28391484	Ph.D.	2	graduate in the field of biotechnology and molecular biology	graduate in the field of biotechnology and molecular biology	Performed the experiments	Investigation	YES
5385187	28391484	SM	2	participated in the design of the study, supervised the work and helped to draft the manuscript|is an associate professor in cellular and molecular sciences at northumbria university	participated in the design of the study, supervised the work and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Original Draft	YES
5385187	28391484	SM	2	participated in the design of the study, supervised the work and helped to draft the manuscript|is an associate professor in cellular and molecular sciences at northumbria university	is an associate professor in cellular and molecular sciences at northumbria university	Performed the experiments	Investigation	YES
5385187	28391484	TK	2	participated in the design of the study, supervised the work and helped to draft the manuscript|is a professor in biotechnology and biochemistry|works as a graduate centre coordinator at university of westminster	participated in the design of the study, supervised the work and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Original Draft	YES
5385187	28391484	TK	2	participated in the design of the study, supervised the work and helped to draft the manuscript|is a professor in biotechnology and biochemistry|works as a graduate centre coordinator at university of westminster	is a professor in biotechnology and biochemistry	Performed the experiments	Investigation	YES
5385187	28391484	TK	2	participated in the design of the study, supervised the work and helped to draft the manuscript|is a professor in biotechnology and biochemistry|works as a graduate centre coordinator at university of westminster	works as a graduate centre coordinator at university of westminster	-	Project administration	YES
5688496	29143667	AM	2	medical supervision	medical supervision	-	Supervision	YES
5688496	29143667	BY	2	molecular lab analysis|statistical analysis	molecular lab analysis	Performed the experiments	Investigation	YES
5688496	29143667	BY	2	molecular lab analysis|statistical analysis	statistical analysis	Analyzed the data	Formal analysis	YES
5688496	29143667	GW	2	molecular lab analysis|statistical analysis|ypp data interpretation|illustration generation|drafting the manuscript|manuscript revision	molecular lab analysis	Performed the experiments	Investigation	YES
5688496	29143667	GW	2	molecular lab analysis|statistical analysis|ypp data interpretation|illustration generation|drafting the manuscript|manuscript revision	statistical analysis	Analyzed the data	Formal analysis	YES
5688496	29143667	GW	2	molecular lab analysis|statistical analysis|ypp data interpretation|illustration generation|drafting the manuscript|manuscript revision	ypp data interpretation	Analyzed the data	Formal analysis	YES
5688496	29143667	GW	2	molecular lab analysis|statistical analysis|ypp data interpretation|illustration generation|drafting the manuscript|manuscript revision	illustration generation	Analyzed the data	Visualization	YES
5688496	29143667	GW	2	molecular lab analysis|statistical analysis|ypp data interpretation|illustration generation|drafting the manuscript|manuscript revision	drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
5688496	29143667	GW	2	molecular lab analysis|statistical analysis|ypp data interpretation|illustration generation|drafting the manuscript|manuscript revision	manuscript revision	Wrote the paper	Writing - Review & Editing	YES
5688496	29143667	JD	2	ak data collection	ak data collection	Performed the experiments	Investigation	YES
5688496	29143667	JDM	2	statistical analysis	statistical analysis	Analyzed the data	Formal analysis	YES
5688496	29143667	JS	2	molecular lab analysis|statistical analysis|ypp data interpretation|drafting the manuscript	molecular lab analysis	Performed the experiments	Investigation	YES
5688496	29143667	JS	2	molecular lab analysis|statistical analysis|ypp data interpretation|drafting the manuscript	statistical analysis	Analyzed the data	Formal analysis	YES
5688496	29143667	JS	2	molecular lab analysis|statistical analysis|ypp data interpretation|drafting the manuscript	ypp data interpretation	Analyzed the data	Formal analysis	YES
5688496	29143667	JS	2	molecular lab analysis|statistical analysis|ypp data interpretation|drafting the manuscript	drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
5688496	29143667	MM	2	ak data collection|molecular lab analysis	ak data collection	Performed the experiments	Investigation	YES
5688496	29143667	MM	2	ak data collection|molecular lab analysis	molecular lab analysis	Performed the experiments	Investigation	YES
5688496	29143667	NF	2	molecular lab analysis	molecular lab analysis	Performed the experiments	Investigation	YES
5688496	29143667	PES	2	statistical analysis|ypp data interpretation|illustration generation|drafting the manuscript	statistical analysis	Analyzed the data	Formal analysis	YES
5688496	29143667	PES	2	statistical analysis|ypp data interpretation|illustration generation|drafting the manuscript	ypp data interpretation	Analyzed the data	Formal analysis	YES
5688496	29143667	PES	2	statistical analysis|ypp data interpretation|illustration generation|drafting the manuscript	illustration generation	Analyzed the data	Visualization	YES
5688496	29143667	PES	2	statistical analysis|ypp data interpretation|illustration generation|drafting the manuscript	drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
5688496	29143667	YPP	2	jd study design|drafting the manuscript|manuscript revision	jd study design	Conceived and designed the experiments	Methodology	YES
5688496	29143667	YPP	2	jd study design|drafting the manuscript|manuscript revision	drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
5688496	29143667	YPP	2	jd study design|drafting the manuscript|manuscript revision	manuscript revision	Wrote the paper	Writing - Review & Editing	YES
5688496	29143667	all authors	2	to comment, further edit and approve the manuscript	to comment, further edit and approve the manuscript	Wrote the paper	Writing - Review & Editing	YES
5010046	27370208	AF	2	planned, performed, and analyzed the experiments	planned, performed, and analyzed the experiments	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation	YES
5010046	27370208	AK	2	planned, performed, and analyzed the experiments	planned, performed, and analyzed the experiments	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation	YES
5010046	27370208	BJR	2	planned, performed, and analyzed the experiments	planned, performed, and analyzed the experiments	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation	YES
5010046	27370208	DK	2	provided reagents and advice	provided reagents and advice	Contributed reagents/materials/analysis tools	Resources	YES
5010046	27370208	FR	2	designed the overall research and wrote the manuscript	designed the overall research and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5010046	27370208	JN	2	planned, performed, and analyzed the experiments	planned, performed, and analyzed the experiments	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation	YES
5010046	27370208	KBB	2	planned, performed, and analyzed the experiments	planned, performed, and analyzed the experiments	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation	YES
5010046	27370208	MA	2	performed and analyzed nmr experiments	performed and analyzed nmr experiments	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5010046	27370208	MB	2	performed and analyzed nmr experiments	performed and analyzed nmr experiments	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5010046	27370208	MK	2	planned, performed, and analyzed the experiments	planned, performed, and analyzed the experiments	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation	YES
5010046	27370208	SAM	2	planned, performed, and analyzed the experiments	planned, performed, and analyzed the experiments	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation	YES
5010046	27370208	SB	2	planned, performed, and analyzed the experiments	planned, performed, and analyzed the experiments	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation	YES
5010046	27370208	TLMT	2	planned, performed, and analyzed the experiments|designed the overall research and wrote the manuscript	planned, performed, and analyzed the experiments	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation	YES
5010046	27370208	TLMT	2	planned, performed, and analyzed the experiments|designed the overall research and wrote the manuscript	designed the overall research and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5539891	28775674	All authors	2	contributed to the development of the study, analysis of data, and read and approved the final manuscript	contributed to the development of the study, analysis of data, and read and approved the final manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5539891	28775674	CE	2	collected data|were major contributors to writing the manuscript	collected data	Performed the experiments	Investigation	YES
5539891	28775674	CE	2	collected data|were major contributors to writing the manuscript	were major contributors to writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5539891	28775674	DE	2	collected data|were major contributors to writing the manuscript	collected data	Performed the experiments	Investigation	YES
5539891	28775674	DE	2	collected data|were major contributors to writing the manuscript	were major contributors to writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5539891	28775674	TL	2	collected data	collected data	Performed the experiments	Investigation	YES
4415997	25928562	AH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Contributed to study design and critically reviewed the manuscript|Approved the version for submission	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415997	25928562	AH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Contributed to study design and critically reviewed the manuscript|Approved the version for submission	Analyzed the data	Analyzed the data	Formal analysis	YES
4415997	25928562	AH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Contributed to study design and critically reviewed the manuscript|Approved the version for submission	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415997	25928562	AH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Contributed to study design and critically reviewed the manuscript|Approved the version for submission	Contributed to study design and critically reviewed the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
4415997	25928562	AH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Contributed to study design and critically reviewed the manuscript|Approved the version for submission	Approved the version for submission	-	-	NO
4415997	25928562	CD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Contributed to study design and data collection, and critically reviewed the manuscript|Approved the version for submission	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415997	25928562	CD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Contributed to study design and data collection, and critically reviewed the manuscript|Approved the version for submission	Analyzed the data	Analyzed the data	Formal analysis	YES
4415997	25928562	CD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Contributed to study design and data collection, and critically reviewed the manuscript|Approved the version for submission	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415997	25928562	CD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Contributed to study design and data collection, and critically reviewed the manuscript|Approved the version for submission	Contributed to study design and data collection, and critically reviewed the manuscript	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Methodology|Resources|Writing - Review & Editing	YES
4415997	25928562	CD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Contributed to study design and data collection, and critically reviewed the manuscript|Approved the version for submission	Approved the version for submission	-	-	NO
4415997	25928562	GA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Contributed to study design and data collection, analysed data, drafted the manuscript, and provided final approval of the version for submission|Approved the version for submission	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415997	25928562	GA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Contributed to study design and data collection, analysed data, drafted the manuscript, and provided final approval of the version for submission|Approved the version for submission	Performed the experiments	Performed the experiments	Investigation	YES
4415997	25928562	GA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Contributed to study design and data collection, analysed data, drafted the manuscript, and provided final approval of the version for submission|Approved the version for submission	Analyzed the data	Analyzed the data	Formal analysis	YES
4415997	25928562	GA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Contributed to study design and data collection, analysed data, drafted the manuscript, and provided final approval of the version for submission|Approved the version for submission	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415997	25928562	GA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Contributed to study design and data collection, analysed data, drafted the manuscript, and provided final approval of the version for submission|Approved the version for submission	Contributed to study design and data collection, analysed data, drafted the manuscript, and provided final approval of the version for submission	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
4415997	25928562	GA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Contributed to study design and data collection, analysed data, drafted the manuscript, and provided final approval of the version for submission|Approved the version for submission	Approved the version for submission	-	-	NO
4415997	25928562	JW	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Contributed to data analysis|Approved the version for submission	Performed the experiments	Performed the experiments	Investigation	YES
4415997	25928562	JW	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Contributed to data analysis|Approved the version for submission	Analyzed the data	Analyzed the data	Formal analysis	YES
4415997	25928562	JW	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Contributed to data analysis|Approved the version for submission	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415997	25928562	JW	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Contributed to data analysis|Approved the version for submission	Contributed to data analysis	Analyzed the data	Formal analysis	YES
4415997	25928562	JW	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Contributed to data analysis|Approved the version for submission	Approved the version for submission	-	-	NO
4415997	25928562	NH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Contributed to data interpretation and critically revised the manuscript|Approved the version for submission	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4415997	25928562	NH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Contributed to data interpretation and critically revised the manuscript|Approved the version for submission	Analyzed the data	Analyzed the data	Formal analysis	YES
4415997	25928562	NH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Contributed to data interpretation and critically revised the manuscript|Approved the version for submission	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415997	25928562	NH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Contributed to data interpretation and critically revised the manuscript|Approved the version for submission	Contributed to data interpretation and critically revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4415997	25928562	NH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Contributed to data interpretation and critically revised the manuscript|Approved the version for submission	Approved the version for submission	-	-	NO
4415997	25928562	TA	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Contributed to data analysis|Approved the version for submission	Performed the experiments	Performed the experiments	Investigation	YES
4415997	25928562	TA	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Contributed to data analysis|Approved the version for submission	Analyzed the data	Analyzed the data	Formal analysis	YES
4415997	25928562	TA	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Contributed to data analysis|Approved the version for submission	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4415997	25928562	TA	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Contributed to data analysis|Approved the version for submission	Contributed to data analysis	Analyzed the data	Formal analysis	YES
4415997	25928562	TA	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Contributed to data analysis|Approved the version for submission	Approved the version for submission	-	-	NO
5770801	29379511	JG	2	acquired and analyzed the data	acquired and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5770801	29379511	JM	2	acquired and analyzed the data	acquired and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5770801	29379511	MM	2	conceptualized and designed the research ideas	conceptualized and designed the research ideas	Conceived and designed the experiments	Conceptualization|Methodology	YES
5770801	29379511	MN	2	conceptualized and designed the research ideas|acquired and analyzed the data	conceptualized and designed the research ideas	Conceived and designed the experiments	Conceptualization|Methodology	YES
5770801	29379511	MN	2	conceptualized and designed the research ideas|acquired and analyzed the data	acquired and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5770801	29379511	PH	2	conceptualized and designed the research ideas	conceptualized and designed the research ideas	Conceived and designed the experiments	Conceptualization|Methodology	YES
5770801	29379511	TLS	2	conceptualized and designed the research ideas|acquired and analyzed the data	conceptualized and designed the research ideas	Conceived and designed the experiments	Conceptualization|Methodology	YES
5770801	29379511	TLS	2	conceptualized and designed the research ideas|acquired and analyzed the data	acquired and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5770801	29379511	TTS	2	conceptualized and designed the research ideas|acquired and analyzed the data	conceptualized and designed the research ideas	Conceived and designed the experiments	Conceptualization|Methodology	YES
5770801	29379511	TTS	2	conceptualized and designed the research ideas|acquired and analyzed the data	acquired and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
1942079	17712423	AJ	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1942079	17712423	AJ	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1942079	17712423	BH	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1942079	17712423	BH	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1942079	17712423	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1942079	17712423	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1942079	17712423	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1942079	17712423	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1942079	17712423	UA	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5388664	28401504	All	2	data is shown in figures, tables and additional files 1 , 2 3 and 4	data is shown in figures, tables and additional files 1 , 2 3 and 4	-	Visualization	YES
5388664	28401504	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5388664	28401504	GC	2	assisted to carry out experiments	assisted to carry out experiments	Performed the experiments	Investigation	YES
5388664	28401504	KS	2	assisted to carry out experiments	assisted to carry out experiments	Performed the experiments	Investigation	YES
5388664	28401504	MHW	2	assisted to carry out experiments	assisted to carry out experiments	Performed the experiments	Investigation	YES
5388664	28401504	TH	2	planned and carried out the experiments, analyzed the data and wrote the manuscript	planned and carried out the experiments, analyzed the data and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
5388664	28401504	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5388664	28401504	XFT	2	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5388664	28401504	ZQW	2	participated in the data analysis and finalized the manuscript	participated in the data analysis and finalized the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4624877	26550573	Jia-Jie Zhang	2	contributed equally to this study and should share first authorship	contributed equally to this study and should share first authorship	-	-	NO
4624877	26550573	Jin-Fang Xing	2	contributed equally to this study	contributed equally to this study	-	-	NO
4624877	26550573	Lian-Fang Du	2	contributed equally to this study	contributed equally to this study	-	-	NO
4624877	26550573	Xiao-Hui Qiao	2	contributed equally to this study and should share first authorship	contributed equally to this study and should share first authorship	-	-	NO
5543556	28785177	AF	2	assisted with the study design, decision making regarding modifications to the questionnaire, and manuscript preparation	assisted with the study design, decision making regarding modifications to the questionnaire, and manuscript preparation	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5543556	28785177	GT	2	designed the study, drafted the first version of the questionnaire, undertook all data analysis, wrote the majority of the manuscript and oversaw the manuscript preparation	designed the study, drafted the first version of the questionnaire, undertook all data analysis, wrote the majority of the manuscript and oversaw the manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Supervision|Writing - Original Draft	YES
5543556	28785177	RB	2	is the chief investigator of the study, assisted with the study design, decision making regarding modifications to the questionnaire, and manuscript preparation	is the chief investigator of the study, assisted with the study design, decision making regarding modifications to the questionnaire, and manuscript preparation	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5543556	28785177	RH	2	assisted with the study design and manuscript preparation	assisted with the study design and manuscript preparation	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5688659	29141604	AT	2	performed the study|wrote the manuscript	performed the study	Performed the experiments	Investigation	YES
5688659	29141604	AT	2	performed the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5688659	29141604	CN	2	performed the study|wrote the manuscript	performed the study	Performed the experiments	Investigation	YES
5688659	29141604	CN	2	performed the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5688659	29141604	JB	2	conceived the study and participated in its design and coordination|wrote the manuscript	conceived the study and participated in its design and coordination	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
5688659	29141604	JB	2	conceived the study and participated in its design and coordination|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5688659	29141604	RPB	2	conceived the study and participated in its design and coordination|wrote the manuscript	conceived the study and participated in its design and coordination	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
5688659	29141604	RPB	2	conceived the study and participated in its design and coordination|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4416000	25928452	GY	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416000	25928452	JG	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416000	25928452	QW	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416000	25928452	XZ	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416000	25928452	ZC	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4416000	25928452	ZC	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4416000	25928452	ZC	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416000	25928452	ZX	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5770892	29379513	JG	2	participated discussion of the results	participated discussion of the results	-	-	NO
5770892	29379513	LL	2	participated discussion of the results	participated discussion of the results	-	-	NO
5069550	27613546	LDC	2	carried out the experiments|performed the analysis|wrote the manuscript	carried out the experiments	Performed the experiments	Investigation	YES
5069550	27613546	LDC	2	carried out the experiments|performed the analysis|wrote the manuscript	performed the analysis	Performed the experiments	Investigation	YES
5069550	27613546	LDC	2	carried out the experiments|performed the analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5069550	27613546	NEZ	2	performed the analysis|wrote the manuscript	performed the analysis	Performed the experiments	Investigation	YES
5069550	27613546	NEZ	2	performed the analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5069550	27613546	RZ	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5069550	27613546	TZ	2	performed the analysis|wrote the manuscript	performed the analysis	Performed the experiments	Investigation	YES
5069550	27613546	TZ	2	performed the analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5069550	27613546	VH	2	carried out the experiments|performed the analysis|wrote the manuscript	carried out the experiments	Performed the experiments	Investigation	YES
5069550	27613546	VH	2	carried out the experiments|performed the analysis|wrote the manuscript	performed the analysis	Performed the experiments	Investigation	YES
5069550	27613546	VH	2	carried out the experiments|performed the analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5392188	28411348	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5392188	28411348	FFZ	2	designed the assays|performed the experiments and data analysis|wrote the manuscript	designed the assays	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5392188	28411348	FFZ	2	designed the assays|performed the experiments and data analysis|wrote the manuscript	performed the experiments and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5392188	28411348	FFZ	2	designed the assays|performed the experiments and data analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5392188	28411348	HL	2	performed the experiments and data analysis	performed the experiments and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5392188	28411348	JQS	2	conceived and designed the project|wrote the manuscript|revised the manuscript	conceived and designed the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5392188	28411348	JQS	2	conceived and designed the project|wrote the manuscript|revised the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5392188	28411348	JQS	2	conceived and designed the project|wrote the manuscript|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5392188	28411348	XYZ	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5392188	28411348	YGZ	2	conceived and designed the project|revised the manuscript	conceived and designed the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5392188	28411348	YGZ	2	conceived and designed the project|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
1942080	17712412	BB	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1942080	17712412	CA	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1942080	17712412	CN	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1942080	17712412	EL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1942080	17712412	EL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1942080	17712412	EL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1942080	17712412	EL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1942080	17712412	GG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1942080	17712412	JG	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1942080	17712412	JT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1942080	17712412	JT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1942080	17712412	JT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1942080	17712412	JT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1942080	17712412	JT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1942080	17712412	SN	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1942080	17712412	SN	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1942080	17712412	SN	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1942080	17712412	TK	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1942080	17712412	XP	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1942080	17712412	XP	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4624878	26550566	Ghislain Moussavou	2	contributed equally to this work	contributed equally to this work	-	-	NO
4624878	26550566	Kisung Ko	2	contributed equally to this work	contributed equally to this work	-	-	NO
5553601	28811750	ARJ	2	assisted with data analysis and manuscript preparation	assisted with data analysis and manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5553601	28811750	JMO	2	assisted with data analysis and manuscript preparation	assisted with data analysis and manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5553601	28811750	JN	2	assisted with manuscript preparation	assisted with manuscript preparation	Wrote the paper	Writing - Original Draft	YES
5553601	28811750	MG	2	assisted with study design and manuscript preparation	assisted with study design and manuscript preparation	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5553601	28811750	MTJ	2	designed the study, oversaw data collection, data analysis and manuscript preparation	designed the study, oversaw data collection, data analysis and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Supervision|Writing - Original Draft	YES
5553601	28811750	MVH	2	assisted with manuscript preparation	assisted with manuscript preparation	Wrote the paper	Writing - Original Draft	YES
5689173	29145803	AM	2	discussed and interpreted the results	discussed and interpreted the results	Analyzed the data	Formal analysis	YES
5689173	29145803	AP	2	discussed and interpreted the results	discussed and interpreted the results	Analyzed the data	Formal analysis	YES
5689173	29145803	CB	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5689173	29145803	CG	2	designed the study|discussed and interpreted the results|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5689173	29145803	CG	2	designed the study|discussed and interpreted the results|wrote the manuscript	discussed and interpreted the results	Analyzed the data	Formal analysis	YES
5689173	29145803	CG	2	designed the study|discussed and interpreted the results|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5689173	29145803	CH	2	discussed and interpreted the results	discussed and interpreted the results	Analyzed the data	Formal analysis	YES
5689173	29145803	FC	2	implemented it|discussed and interpreted the results|wrote the manuscript	implemented it	Performed the experiments	Investigation	YES
5689173	29145803	FC	2	implemented it|discussed and interpreted the results|wrote the manuscript	discussed and interpreted the results	Analyzed the data	Formal analysis	YES
5689173	29145803	FC	2	implemented it|discussed and interpreted the results|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5689173	29145803	HC	2	designed the study|discussed and interpreted the results|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5689173	29145803	HC	2	designed the study|discussed and interpreted the results|wrote the manuscript	discussed and interpreted the results	Analyzed the data	Formal analysis	YES
5689173	29145803	HC	2	designed the study|discussed and interpreted the results|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5689173	29145803	LM	2	discussed and interpreted the results|wrote the manuscript	discussed and interpreted the results	Analyzed the data	Formal analysis	YES
5689173	29145803	LM	2	discussed and interpreted the results|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5689173	29145803	MD	2	discussed and interpreted the results|wrote the manuscript	discussed and interpreted the results	Analyzed the data	Formal analysis	YES
5689173	29145803	MD	2	discussed and interpreted the results|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5689173	29145803	OD	2	discussed and interpreted the results|wrote the manuscript	discussed and interpreted the results	Analyzed the data	Formal analysis	YES
5689173	29145803	OD	2	discussed and interpreted the results|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5689173	29145803	PC	2	discussed and interpreted the results|coordinated the bacnet project	discussed and interpreted the results	Analyzed the data	Formal analysis	YES
5689173	29145803	PC	2	discussed and interpreted the results|coordinated the bacnet project	coordinated the bacnet project	-	Project administration	YES
4416001	25928148	ALC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416001	25928148	DSD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416001	25928148	DSD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416001	25928148	DSD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416001	25928148	DSD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416001	25928148	GNB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416001	25928148	GNB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416001	25928148	GNB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416001	25928148	JL	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416001	25928148	JL	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416001	25928148	JLW	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416001	25928148	JLW	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416001	25928148	MAM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416001	25928148	MAM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416001	25928148	MAM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416001	25928148	MAM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416001	25928148	SA	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416001	25928148	SAA	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416001	25928148	SAA	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416001	25928148	SMP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416001	25928148	VGS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416001	25928148	VGS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4416001	25928148	VGS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5771210	29379518	All authors	2	participated in the revision and agree with the final manuscript	participated in the revision and agree with the final manuscript	Wrote the paper	Writing - Review & Editing	YES
1942081	17712413	AO	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1942081	17712413	AO	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1942081	17712413	AO	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1942081	17712413	MA	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1942081	17712413	MA	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1942081	17712413	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1942081	17712413	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1942081	17712413	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1942081	17712413	OB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1942081	17712413	OB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1942081	17712413	OB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1942081	17712413	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1942081	17712413	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1942081	17712413	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1942081	17712413	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1942081	17712413	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1942081	17712413	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1942081	17712413	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5069555	27647875	AF	2	prepared stable cell lines, rnas, and cdna libraries for high-throughput sequencing	prepared stable cell lines, rnas, and cdna libraries for high-throughput sequencing	Performed the experiments	Investigation	YES
5069555	27647875	DU	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5069555	27647875	JP	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5069555	27647875	MZ	2	helped with the design and interpretation of bioinformatics analyses and manuscript preparation	helped with the design and interpretation of bioinformatics analyses and manuscript preparation	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5069555	27647875	SV	2	conceived, designed and interpreted experiments, and supervised the project|wrote the manuscript	conceived, designed and interpreted experiments, and supervised the project	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology|Supervision	YES
5069555	27647875	SV	2	conceived, designed and interpreted experiments, and supervised the project|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5392452	28413853	HHZ	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5392452	28413853	HXZ	PLoS5	Analyzed the date	Analyzed the date	Analyzed the data	Formal analysis	YES
5392452	28413853	JC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the date|Contributed materials|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5392452	28413853	JC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the date|Contributed materials|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
5392452	28413853	JC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the date|Contributed materials|Wrote the paper	Analyzed the date	Analyzed the data	Formal analysis	YES
5392452	28413853	JC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the date|Contributed materials|Wrote the paper	Contributed materials	Contributed reagents/materials/analysis tools	Resources	YES
5392452	28413853	JC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the date|Contributed materials|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5392452	28413853	JKY	PLoS5	Contributed materials	Contributed materials	Contributed reagents/materials/analysis tools	Resources	YES
5392452	28413853	SS	PLoS5	Contributed materials	Contributed materials	Contributed reagents/materials/analysis tools	Resources	YES
5392452	28413853	XXT	PLoS5	Modify the manuscript	Modify the manuscript	Wrote the paper	Writing - Review & Editing	YES
5392452	28413853	XYW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5392452	28413853	YC	PLoS5	Contributed materials	Contributed materials	Contributed reagents/materials/analysis tools	Resources	YES
4416002	25927922	C. Yang	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4416002	25927922	C. Yang	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416002	25927922	PJ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416002	25927922	PW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416002	25927922	QF	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416002	25927922	QF	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416002	25927922	QF	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416002	25927922	Xuemin Wang	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416002	25927922	Xuemin Wang	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416002	25927922	Xuemin Wang	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416002	25927922	Xuerong Wang	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4416002	25927922	Xuerong Wang	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5771374	29379517	All authors	2	contributed to the writing of this manuscript	contributed to the writing of this manuscript	Wrote the paper	Writing - Original Draft	YES
5912187	29564967	SND	2	created the study concept, design and methodology|carried out data collection and data entry|analysed and interpreted the data|drafted, critically reviewed, commented on and revised the manuscript	created the study concept, design and methodology	Conceived and designed the experiments|Performed the experiments	Conceptualization|Methodology	YES
5912187	29564967	SND	2	created the study concept, design and methodology|carried out data collection and data entry|analysed and interpreted the data|drafted, critically reviewed, commented on and revised the manuscript	carried out data collection and data entry	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5912187	29564967	SND	2	created the study concept, design and methodology|carried out data collection and data entry|analysed and interpreted the data|drafted, critically reviewed, commented on and revised the manuscript	analysed and interpreted the data	Analyzed the data	Formal analysis	YES
5912187	29564967	SND	2	created the study concept, design and methodology|carried out data collection and data entry|analysed and interpreted the data|drafted, critically reviewed, commented on and revised the manuscript	drafted, critically reviewed, commented on and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5912187	29564967	TAT	2	created the study concept, design and methodology|supervised data collection and data entry|analysed and interpreted the data|drafted, critically reviewed, commented on and revised the manuscript	created the study concept, design and methodology	Conceived and designed the experiments|Performed the experiments	Conceptualization|Methodology	YES
5912187	29564967	TAT	2	created the study concept, design and methodology|supervised data collection and data entry|analysed and interpreted the data|drafted, critically reviewed, commented on and revised the manuscript	supervised data collection and data entry	Performed the experiments|Analyzed the data	Data curation|Investigation|Supervision	YES
5912187	29564967	TAT	2	created the study concept, design and methodology|supervised data collection and data entry|analysed and interpreted the data|drafted, critically reviewed, commented on and revised the manuscript	analysed and interpreted the data	Analyzed the data	Formal analysis	YES
5912187	29564967	TAT	2	created the study concept, design and methodology|supervised data collection and data entry|analysed and interpreted the data|drafted, critically reviewed, commented on and revised the manuscript	drafted, critically reviewed, commented on and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5912187	29564967	TB	2	supervised data collection and data entry|analysed and interpreted the data|drafted, critically reviewed, commented on and revised the manuscript	supervised data collection and data entry	Performed the experiments|Analyzed the data	Data curation|Investigation|Supervision	YES
5912187	29564967	TB	2	supervised data collection and data entry|analysed and interpreted the data|drafted, critically reviewed, commented on and revised the manuscript	analysed and interpreted the data	Analyzed the data	Formal analysis	YES
5912187	29564967	TB	2	supervised data collection and data entry|analysed and interpreted the data|drafted, critically reviewed, commented on and revised the manuscript	drafted, critically reviewed, commented on and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5553796	28811748	AA	2	conceived the study and participated in the design of the study|organised data collection|conducted statistical analysis|helped to draft the manuscript	conceived the study and participated in the design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5553796	28811748	AA	2	conceived the study and participated in the design of the study|organised data collection|conducted statistical analysis|helped to draft the manuscript	organised data collection	Performed the experiments	Investigation	YES
5553796	28811748	AA	2	conceived the study and participated in the design of the study|organised data collection|conducted statistical analysis|helped to draft the manuscript	conducted statistical analysis	Analyzed the data	Formal analysis	YES
5553796	28811748	AA	2	conceived the study and participated in the design of the study|organised data collection|conducted statistical analysis|helped to draft the manuscript	helped to draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5553796	28811748	CS	2	conducted statistical analysis|helped to draft the manuscript	conducted statistical analysis	Analyzed the data	Formal analysis	YES
5553796	28811748	CS	2	conducted statistical analysis|helped to draft the manuscript	helped to draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5553796	28811748	DKD	2	conceived the study and participated in the design of the study	conceived the study and participated in the design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5553796	28811748	KRM	2	conceived the study and participated in the design of the study|completed biochemical assays|helped to draft the manuscript	conceived the study and participated in the design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5553796	28811748	KRM	2	conceived the study and participated in the design of the study|completed biochemical assays|helped to draft the manuscript	completed biochemical assays	Performed the experiments	Investigation	YES
5553796	28811748	KRM	2	conceived the study and participated in the design of the study|completed biochemical assays|helped to draft the manuscript	helped to draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5689174	29145801	AGP	PLoS5	Conceived the project|Designed the experiments|Critically revised the manuscript|Lead the project	Conceived the project	Conceived and designed the experiments	Conceptualization	YES
5689174	29145801	AGP	PLoS5	Conceived the project|Designed the experiments|Critically revised the manuscript|Lead the project	Designed the experiments	Conceived and designed the experiments	Methodology	YES
5689174	29145801	AGP	PLoS5	Conceived the project|Designed the experiments|Critically revised the manuscript|Lead the project	Critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5689174	29145801	AGP	PLoS5	Conceived the project|Designed the experiments|Critically revised the manuscript|Lead the project	Lead the project	-	-	NO
5689174	29145801	AL	PLoS5	Contributed to material and data acquisition|Analyzed the data|Designed the experiments|Critically revised the manuscript	Contributed to material and data acquisition	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5689174	29145801	AL	PLoS5	Contributed to material and data acquisition|Analyzed the data|Designed the experiments|Critically revised the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
5689174	29145801	AL	PLoS5	Contributed to material and data acquisition|Analyzed the data|Designed the experiments|Critically revised the manuscript	Designed the experiments	Conceived and designed the experiments	Methodology	YES
5689174	29145801	AL	PLoS5	Contributed to material and data acquisition|Analyzed the data|Designed the experiments|Critically revised the manuscript	Critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5689174	29145801	GP	PLoS5	Contributed to material and data acquisition|Designed the experiments|Critically revised the manuscript	Contributed to material and data acquisition	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5689174	29145801	GP	PLoS5	Contributed to material and data acquisition|Designed the experiments|Critically revised the manuscript	Designed the experiments	Conceived and designed the experiments	Methodology	YES
5689174	29145801	GP	PLoS5	Contributed to material and data acquisition|Designed the experiments|Critically revised the manuscript	Critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5689174	29145801	IGV	PLoS5	Lead the project	Lead the project	-	-	NO
5689174	29145801	IVG	PLoS5	Designed the experiments|Critically revised the manuscript	Designed the experiments	Conceived and designed the experiments	Methodology	YES
5689174	29145801	IVG	PLoS5	Designed the experiments|Critically revised the manuscript	Critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5689174	29145801	JA	PLoS5	Contributed to material and data acquisition|Designed the experiments|Critically revised the manuscript	Contributed to material and data acquisition	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5689174	29145801	JA	PLoS5	Contributed to material and data acquisition|Designed the experiments|Critically revised the manuscript	Designed the experiments	Conceived and designed the experiments	Methodology	YES
5689174	29145801	JA	PLoS5	Contributed to material and data acquisition|Designed the experiments|Critically revised the manuscript	Critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5689174	29145801	KB	PLoS5	Contributed to material and data acquisition|Designed the experiments|Critically revised the manuscript	Contributed to material and data acquisition	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5689174	29145801	KB	PLoS5	Contributed to material and data acquisition|Designed the experiments|Critically revised the manuscript	Designed the experiments	Conceived and designed the experiments	Methodology	YES
5689174	29145801	KB	PLoS5	Contributed to material and data acquisition|Designed the experiments|Critically revised the manuscript	Critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5689174	29145801	KL	PLoS5	Contributed to material and data acquisition|Analyzed the data|Designed the experiments|Critically revised the manuscript	Contributed to material and data acquisition	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5689174	29145801	KL	PLoS5	Contributed to material and data acquisition|Analyzed the data|Designed the experiments|Critically revised the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
5689174	29145801	KL	PLoS5	Contributed to material and data acquisition|Analyzed the data|Designed the experiments|Critically revised the manuscript	Designed the experiments	Conceived and designed the experiments	Methodology	YES
5689174	29145801	KL	PLoS5	Contributed to material and data acquisition|Analyzed the data|Designed the experiments|Critically revised the manuscript	Critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5689174	29145801	LLV	PLoS5	Contributed to material and data acquisition|Designed the experiments|Critically revised the manuscript	Contributed to material and data acquisition	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5689174	29145801	LLV	PLoS5	Contributed to material and data acquisition|Designed the experiments|Critically revised the manuscript	Designed the experiments	Conceived and designed the experiments	Methodology	YES
5689174	29145801	LLV	PLoS5	Contributed to material and data acquisition|Designed the experiments|Critically revised the manuscript	Critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5689174	29145801	LR	PLoS5	Conceived the project|Designed the experiments|Critically revised the manuscript|Lead the project	Conceived the project	Conceived and designed the experiments	Conceptualization	YES
5689174	29145801	LR	PLoS5	Conceived the project|Designed the experiments|Critically revised the manuscript|Lead the project	Designed the experiments	Conceived and designed the experiments	Methodology	YES
5689174	29145801	LR	PLoS5	Conceived the project|Designed the experiments|Critically revised the manuscript|Lead the project	Critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5689174	29145801	LR	PLoS5	Conceived the project|Designed the experiments|Critically revised the manuscript|Lead the project	Lead the project	-	-	NO
5689174	29145801	RC	PLoS5	Conceived the project|Wrote the article|Contributed to material and data acquisition|Analyzed the data|Designed the experiments|Critically revised the manuscript	Conceived the project	Conceived and designed the experiments	Conceptualization	YES
5689174	29145801	RC	PLoS5	Conceived the project|Wrote the article|Contributed to material and data acquisition|Analyzed the data|Designed the experiments|Critically revised the manuscript	Wrote the article	Wrote the paper	Writing - Original Draft	YES
5689174	29145801	RC	PLoS5	Conceived the project|Wrote the article|Contributed to material and data acquisition|Analyzed the data|Designed the experiments|Critically revised the manuscript	Contributed to material and data acquisition	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5689174	29145801	RC	PLoS5	Conceived the project|Wrote the article|Contributed to material and data acquisition|Analyzed the data|Designed the experiments|Critically revised the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
5689174	29145801	RC	PLoS5	Conceived the project|Wrote the article|Contributed to material and data acquisition|Analyzed the data|Designed the experiments|Critically revised the manuscript	Designed the experiments	Conceived and designed the experiments	Methodology	YES
5689174	29145801	RC	PLoS5	Conceived the project|Wrote the article|Contributed to material and data acquisition|Analyzed the data|Designed the experiments|Critically revised the manuscript	Critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5689174	29145801	SH	PLoS5	Contributed to material and data acquisition|Analyzed the data|Designed the experiments|Critically revised the manuscript	Contributed to material and data acquisition	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5689174	29145801	SH	PLoS5	Contributed to material and data acquisition|Analyzed the data|Designed the experiments|Critically revised the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
5689174	29145801	SH	PLoS5	Contributed to material and data acquisition|Analyzed the data|Designed the experiments|Critically revised the manuscript	Designed the experiments	Conceived and designed the experiments	Methodology	YES
5689174	29145801	SH	PLoS5	Contributed to material and data acquisition|Analyzed the data|Designed the experiments|Critically revised the manuscript	Critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5689174	29145801	VS	PLoS5	Contributed to material and data acquisition|Analyzed the data|Designed the experiments|Critically revised the manuscript	Contributed to material and data acquisition	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5689174	29145801	VS	PLoS5	Contributed to material and data acquisition|Analyzed the data|Designed the experiments|Critically revised the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
5689174	29145801	VS	PLoS5	Contributed to material and data acquisition|Analyzed the data|Designed the experiments|Critically revised the manuscript	Designed the experiments	Conceived and designed the experiments	Methodology	YES
5689174	29145801	VS	PLoS5	Contributed to material and data acquisition|Analyzed the data|Designed the experiments|Critically revised the manuscript	Critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
1942082	17712414	CL	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1942082	17712414	CL	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1942082	17712414	DB	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1942082	17712414	DB	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1942082	17712414	FK	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1942082	17712414	KD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1942082	17712414	KD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1942082	17712414	KD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1942082	17712414	ML	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1942082	17712414	ML	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1942082	17712414	OW	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1942082	17712414	RO	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1942082	17712414	RO	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1942082	17712414	SA	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1942082	17712414	SH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1942082	17712414	SH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1942082	17712414	SH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5393979	28417435	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5393979	28417435	CSTC	2	authors declare that they have no competing interests	authors declare that they have no competing interests	-	-	NO
5393979	28417435	CY	2	carried out sequence analysis	carried out sequence analysis	Performed the experiments	Investigation	YES
5393979	28417435	GG	2	conceived of the study, and participated in its design and coordination and helped to draft the manuscript	conceived of the study, and participated in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
5393979	28417435	HS	2	draft the manuscript	draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5393979	28417435	KL	2	participated in the statistical analysis	participated in the statistical analysis	Analyzed the data	Formal analysis	YES
5393979	28417435	QZ	2	conceived of the study, and participated in its design and coordination and helped to draft the manuscript	conceived of the study, and participated in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
5393979	28417435	SC	2	participated in the statistical analysis	participated in the statistical analysis	Analyzed the data	Formal analysis	YES
5393979	28417435	SL	2	carried out the animal stress model studies	carried out the animal stress model studies	Performed the experiments	Investigation|Methodology	YES
5393979	28417435	SY	2	carried out sequence analysis	carried out sequence analysis	Performed the experiments	Investigation	YES
5393979	28417435	YY	2	carried out the animal stress model studies	carried out the animal stress model studies	Performed the experiments	Investigation|Methodology	YES
5393979	28417435	ZW	2	carried out the animal stress model studies|draft the manuscript	carried out the animal stress model studies	Performed the experiments	Investigation|Methodology	YES
5393979	28417435	ZW	2	carried out the animal stress model studies|draft the manuscript	draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5109238	27707753	BM	PLoS52	performed experiments|analyzed data	performed experiments	Performed the experiments	Investigation	YES
5109238	27707753	BM	PLoS52	performed experiments|analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5109238	27707753	CE	PLoS52	designed experiments|performed experiments|analyzed data	designed experiments	Conceived and designed the experiments	Methodology	YES
5109238	27707753	CE	PLoS52	designed experiments|performed experiments|analyzed data	performed experiments	Performed the experiments	Investigation	YES
5109238	27707753	CE	PLoS52	designed experiments|performed experiments|analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5109238	27707753	DG	PLoS52	conceived the study|designed experiments|analyzed data|wrote the paper|supervised the project	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5109238	27707753	DG	PLoS52	conceived the study|designed experiments|analyzed data|wrote the paper|supervised the project	designed experiments	Conceived and designed the experiments	Methodology	YES
5109238	27707753	DG	PLoS52	conceived the study|designed experiments|analyzed data|wrote the paper|supervised the project	analyzed data	Analyzed the data	Formal analysis	YES
5109238	27707753	DG	PLoS52	conceived the study|designed experiments|analyzed data|wrote the paper|supervised the project	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5109238	27707753	DG	PLoS52	conceived the study|designed experiments|analyzed data|wrote the paper|supervised the project	supervised the project	-	Supervision	YES
5109238	27707753	HZ	PLoS52	provided reagents	provided reagents	Contributed reagents/materials/analysis tools	Resources	YES
5109238	27707753	JAK	PLoS52	designed experiments|analyzed data|wrote the paper	designed experiments	Conceived and designed the experiments	Methodology	YES
5109238	27707753	JAK	PLoS52	designed experiments|analyzed data|wrote the paper	analyzed data	Analyzed the data	Formal analysis	YES
5109238	27707753	JAK	PLoS52	designed experiments|analyzed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5109238	27707753	JPF	PLoS52	conceived the study|designed experiments|performed experiments|analyzed data|wrote the paper	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5109238	27707753	JPF	PLoS52	conceived the study|designed experiments|performed experiments|analyzed data|wrote the paper	designed experiments	Conceived and designed the experiments	Methodology	YES
5109238	27707753	JPF	PLoS52	conceived the study|designed experiments|performed experiments|analyzed data|wrote the paper	performed experiments	Performed the experiments	Investigation	YES
5109238	27707753	JPF	PLoS52	conceived the study|designed experiments|performed experiments|analyzed data|wrote the paper	analyzed data	Analyzed the data	Formal analysis	YES
5109238	27707753	JPF	PLoS52	conceived the study|designed experiments|performed experiments|analyzed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5109238	27707753	KE	PLoS52	provided reagents	provided reagents	Contributed reagents/materials/analysis tools	Resources	YES
5109238	27707753	RS	PLoS52	performed experiments|analyzed data	performed experiments	Performed the experiments	Investigation	YES
5109238	27707753	RS	PLoS52	performed experiments|analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5109238	27707753	SY	PLoS52	provided reagents	provided reagents	Contributed reagents/materials/analysis tools	Resources	YES
5109238	27707753	WY	PLoS52	provided reagents	provided reagents	Contributed reagents/materials/analysis tools	Resources	YES
3871506	24381519	Andreas Podbielski	2	contributed equally to this study	contributed equally to this study	-	-	NO
3871506	24381519	Rainer Bader	2	contributed equally to this study	contributed equally to this study	-	-	NO
4416005	25928634	FB	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416005	25928634	FB	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416005	25928634	FB	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416005	25928634	FB	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416005	25928634	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416005	25928634	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416005	25928634	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416005	25928634	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416005	25928634	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416005	25928634	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416005	25928634	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416005	25928634	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416005	25928634	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416005	25928634	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5553857	28811749	BA	1	Manuscript writing	Manuscript writing	Wrote the paper	Writing - Original Draft	YES
5553857	28811749	DA	1	Biochemical analyses	Biochemical analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5553857	28811749	DL	1	Experimental design|Data acquisition|Data interpretation|Manuscript writing	Experimental design	Conceived and designed the experiments	Methodology	YES
5553857	28811749	DL	1	Experimental design|Data acquisition|Data interpretation|Manuscript writing	Data acquisition	Performed the experiments	Investigation	YES
5553857	28811749	DL	1	Experimental design|Data acquisition|Data interpretation|Manuscript writing	Data interpretation	Analyzed the data	Formal analysis	YES
5553857	28811749	DL	1	Experimental design|Data acquisition|Data interpretation|Manuscript writing	Manuscript writing	Wrote the paper	Writing - Original Draft	YES
5553857	28811749	DRM	1	Biochemical analyses	Biochemical analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5553857	28811749	HE	1	Data interpretation|Manuscript writing	Data interpretation	Analyzed the data	Formal analysis	YES
5553857	28811749	HE	1	Data interpretation|Manuscript writing	Manuscript writing	Wrote the paper	Writing - Original Draft	YES
5553857	28811749	MR	1	Experimental design|Data interpretation|Manuscript writing	Experimental design	Conceived and designed the experiments	Methodology	YES
5553857	28811749	MR	1	Experimental design|Data interpretation|Manuscript writing	Data interpretation	Analyzed the data	Formal analysis	YES
5553857	28811749	MR	1	Experimental design|Data interpretation|Manuscript writing	Manuscript writing	Wrote the paper	Writing - Original Draft	YES
5553857	28811749	SDD	1	Data acquisition|Manuscript writing	Data acquisition	Performed the experiments	Investigation	YES
5553857	28811749	SDD	1	Data acquisition|Manuscript writing	Manuscript writing	Wrote the paper	Writing - Original Draft	YES
5553857	28811749	SW	1	Biochemical analyses|Data interpretation	Biochemical analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5553857	28811749	SW	1	Biochemical analyses|Data interpretation	Data interpretation	Analyzed the data	Formal analysis	YES
5553857	28811749	TC	1	Experimental design|Data acquisition|Manuscript writing	Experimental design	Conceived and designed the experiments	Methodology	YES
5553857	28811749	TC	1	Experimental design|Data acquisition|Manuscript writing	Data acquisition	Performed the experiments	Investigation	YES
5553857	28811749	TC	1	Experimental design|Data acquisition|Manuscript writing	Manuscript writing	Wrote the paper	Writing - Original Draft	YES
5553857	28811749	WA	1	Data interpretation|Manuscript writing	Data interpretation	Analyzed the data	Formal analysis	YES
5553857	28811749	WA	1	Data interpretation|Manuscript writing	Manuscript writing	Wrote the paper	Writing - Original Draft	YES
5775212	29379514	JL	PLoS52	analyzed the data and made the figures	analyzed the data and made the figures	Analyzed the data	Formal analysis|Visualization	YES
5775212	29379514	JZ	PLoS52	conceived and designed the experiments|executed the experiment and measured the data|analyzed the data and made the figures|wrote the paper|revised the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5775212	29379514	JZ	PLoS52	conceived and designed the experiments|executed the experiment and measured the data|analyzed the data and made the figures|wrote the paper|revised the paper	executed the experiment and measured the data	Performed the experiments	Investigation	YES
5775212	29379514	JZ	PLoS52	conceived and designed the experiments|executed the experiment and measured the data|analyzed the data and made the figures|wrote the paper|revised the paper	analyzed the data and made the figures	Analyzed the data	Formal analysis|Visualization	YES
5775212	29379514	JZ	PLoS52	conceived and designed the experiments|executed the experiment and measured the data|analyzed the data and made the figures|wrote the paper|revised the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5775212	29379514	JZ	PLoS52	conceived and designed the experiments|executed the experiment and measured the data|analyzed the data and made the figures|wrote the paper|revised the paper	revised the paper	Wrote the paper	Writing - Review & Editing	YES
5775212	29379514	L-DZ	PLoS52	executed the experiment and measured the data|analyzed the data and made the figures|revised the paper	executed the experiment and measured the data	Performed the experiments	Investigation	YES
5775212	29379514	L-DZ	PLoS52	executed the experiment and measured the data|analyzed the data and made the figures|revised the paper	analyzed the data and made the figures	Analyzed the data	Formal analysis|Visualization	YES
5775212	29379514	L-DZ	PLoS52	executed the experiment and measured the data|analyzed the data and made the figures|revised the paper	revised the paper	Wrote the paper	Writing - Review & Editing	YES
5775212	29379514	L-JC	PLoS52	conceived and designed the experiments|contributed to writing and editing the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5775212	29379514	L-JC	PLoS52	conceived and designed the experiments|contributed to writing and editing the manuscript	contributed to writing and editing the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5775212	29379514	M-XZ	PLoS52	revised the paper	revised the paper	Wrote the paper	Writing - Review & Editing	YES
5775212	29379514	WL	PLoS52	contributed to writing and editing the manuscript	contributed to writing and editing the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5775212	29379514	X-MK	PLoS52	contributed to writing and editing the manuscript	contributed to writing and editing the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5775212	29379514	XP	PLoS52	executed the experiment and measured the data	executed the experiment and measured the data	Performed the experiments	Investigation	YES
5775212	29379514	YN	PLoS52	executed the experiment and measured the data	executed the experiment and measured the data	Performed the experiments	Investigation	YES
1942083	17712415	AS	PLoS5	Performed the experiments|Wrote the paper|Generated the retrovirus|Performed the transduction experiments	Performed the experiments	Performed the experiments	Investigation	YES
1942083	17712415	AS	PLoS5	Performed the experiments|Wrote the paper|Generated the retrovirus|Performed the transduction experiments	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1942083	17712415	AS	PLoS5	Performed the experiments|Wrote the paper|Generated the retrovirus|Performed the transduction experiments	Generated the retrovirus	Performed the experiments	Investigation	YES
1942083	17712415	AS	PLoS5	Performed the experiments|Wrote the paper|Generated the retrovirus|Performed the transduction experiments	Performed the transduction experiments	Performed the experiments	Investigation	YES
1942083	17712415	BL	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1942083	17712415	BL	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1942083	17712415	HN	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1942083	17712415	HN	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1942083	17712415	HN	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1942083	17712415	KB	PLoS5	Provided input into experimental design|Provided comments on the manuscript	Provided input into experimental design	Conceived and designed the experiments	Methodology	YES
1942083	17712415	KB	PLoS5	Provided input into experimental design|Provided comments on the manuscript	Provided comments on the manuscript	-	-	NO
5691397	29145825	All authors	2	reviewed and approved the final manuscript	reviewed and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5691397	29145825	CW	2	performed the genome and transcriptome assembly, analysis|performed dna and rna extractions|prepared the manuscript draft	performed the genome and transcriptome assembly, analysis	Performed the experiments	Investigation	YES
5691397	29145825	CW	2	performed the genome and transcriptome assembly, analysis|performed dna and rna extractions|prepared the manuscript draft	performed dna and rna extractions	Performed the experiments	Investigation	YES
5691397	29145825	CW	2	performed the genome and transcriptome assembly, analysis|performed dna and rna extractions|prepared the manuscript draft	prepared the manuscript draft	Wrote the paper	Writing - Original Draft	YES
5691397	29145825	RDN	2	conceived and designed the project and advised on analyses|edited and commented extensively on the draft manuscript	conceived and designed the project and advised on analyses	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
5691397	29145825	RDN	2	conceived and designed the project and advised on analyses|edited and commented extensively on the draft manuscript	edited and commented extensively on the draft manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5691397	29145825	RNC	2	provided valuable suggestions and participated in the bioinformatics analysis|edited and commented extensively on the draft manuscript	provided valuable suggestions and participated in the bioinformatics analysis	-	Formal analysis	YES
5691397	29145825	RNC	2	provided valuable suggestions and participated in the bioinformatics analysis|edited and commented extensively on the draft manuscript	edited and commented extensively on the draft manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5691397	29145825	TRB	2	conceived and designed the project and advised on analyses|edited and commented extensively on the draft manuscript	conceived and designed the project and advised on analyses	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
5691397	29145825	TRB	2	conceived and designed the project and advised on analyses|edited and commented extensively on the draft manuscript	edited and commented extensively on the draft manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5691397	29145825	VGT	2	performed flow cytometry experiment|performed dna and rna extractions	performed flow cytometry experiment	Performed the experiments	Investigation	YES
5691397	29145825	VGT	2	performed flow cytometry experiment|performed dna and rna extractions	performed dna and rna extractions	Performed the experiments	Investigation	YES
5399010	28429328	HY	1	Planning and designing of study|Experimentation and result analysis|Drafting	Planning and designing of study	Conceived and designed the experiments	Methodology	YES
5399010	28429328	HY	1	Planning and designing of study|Experimentation and result analysis|Drafting	Experimentation and result analysis	Performed the experiments	Investigation	YES
5399010	28429328	HY	1	Planning and designing of study|Experimentation and result analysis|Drafting	Drafting	Wrote the paper	Writing - Original Draft	YES
5399010	28429328	MU	1	Planning and designing of study|Drafting	Planning and designing of study	Conceived and designed the experiments	Methodology	YES
5399010	28429328	MU	1	Planning and designing of study|Drafting	Drafting	Wrote the paper	Writing - Original Draft	YES
5399010	28429328	WA	1	Planning and designing of study|Drafting	Planning and designing of study	Conceived and designed the experiments	Methodology	YES
5399010	28429328	WA	1	Planning and designing of study|Drafting	Drafting	Wrote the paper	Writing - Original Draft	YES
5399010	28429328	YM	1	Planning and designing of study|Experimentation and result analysis|Drafting	Planning and designing of study	Conceived and designed the experiments	Methodology	YES
5399010	28429328	YM	1	Planning and designing of study|Experimentation and result analysis|Drafting	Experimentation and result analysis	Performed the experiments	Investigation	YES
5399010	28429328	YM	1	Planning and designing of study|Experimentation and result analysis|Drafting	Drafting	Wrote the paper	Writing - Original Draft	YES
5399010	28429328	YT	1	Planning and designing of study|Drafting	Planning and designing of study	Conceived and designed the experiments	Methodology	YES
5399010	28429328	YT	1	Planning and designing of study|Drafting	Drafting	Wrote the paper	Writing - Original Draft	YES
4416006	25928139	JPG	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416006	25928139	JPG	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416006	25928139	JPG	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416006	25928139	MK	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416006	25928139	MK	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416006	25928139	RR	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416006	25928139	RR	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416006	25928139	SKS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416006	25928139	SKS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416006	25928139	SKS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416006	25928139	SKS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3871911	24381516	Shuangshuang Huang	2	contributed equally to this work	contributed equally to this work	-	-	NO
3871911	24381516	Xiang Li	2	contributed equally to this work	contributed equally to this work	-	-	NO
5109244	27753620	CRS	2	designed and coordinated the study and wrote the manuscript	designed and coordinated the study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft	YES
5109244	27753620	HF	2	provided assistance in generating reagents	provided assistance in generating reagents	Performed the experiments|Contributed reagents/materials/analysis tools	Resources	YES
5109244	27753620	OS	2	provided technical assistance, contributed to the design of experiments, and performed some of the experiments shown in fig 8	provided technical assistance, contributed to the design of experiments, and performed some of the experiments shown in fig 8	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Visualization	YES
5109244	27753620	PH	2	designed the study, performed and analyzed experiments, and wrote the manuscript	designed the study, performed and analyzed experiments, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5109244	27753620	SK	2	provided technical assistance and contributed to the design of experiments	provided technical assistance and contributed to the design of experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5109244	27753620	SRM	2	performed and analyzed the experiments shown in fig 5	performed and analyzed the experiments shown in fig 5	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
1942084	17712404	CG	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1942084	17712404	DK	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1942084	17712404	DS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1942084	17712404	EH	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1942084	17712404	FL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1942084	17712404	FL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1942084	17712404	FL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1942084	17712404	FL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1942084	17712404	FS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1942084	17712404	JH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1942084	17712404	JH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1942084	17712404	JH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1942084	17712404	JH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1942084	17712404	JK	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1942084	17712404	LK	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1942084	17712404	SB	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1942084	17712404	SB	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1942084	17712404	SG	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1942084	17712404	SR	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1942084	17712404	TT	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1942084	17712404	TT	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5568273	28852372	RRW	2	has drafted, read and approved the final manuscript	has drafted, read and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4416007	25928215	LX	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416007	25928215	MY	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416007	25928215	MY	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416007	25928215	MY	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416007	25928215	MY	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416007	25928215	PY	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416007	25928215	PY	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416007	25928215	YL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416007	25928215	YL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416007	25928215	YL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5775218	29379516	FH	4	The experiments were performed by	The experiments were performed by	Performed the experiments	Investigation	YES
5775218	29379516	HG	4	This research was designed by|the data were analyzed by|The manuscript was written by	This research was designed by	Conceived and designed the experiments	-	YES
5775218	29379516	HG	4	This research was designed by|the data were analyzed by|The manuscript was written by	the data were analyzed by	Analyzed the data	Formal analysis	YES
5775218	29379516	HG	4	This research was designed by|the data were analyzed by|The manuscript was written by	The manuscript was written by	Wrote the paper	Writing - Original Draft	YES
5775218	29379516	JY	4	The experiments were performed by	The experiments were performed by	Performed the experiments	Investigation	YES
5775218	29379516	QZ	4	The experiments were performed by	The experiments were performed by	Performed the experiments	Investigation	YES
5775218	29379516	WJ	4	The experiments were performed by|the data were analyzed by|The manuscript was written by	The experiments were performed by	Performed the experiments	Investigation	YES
5775218	29379516	WJ	4	The experiments were performed by|the data were analyzed by|The manuscript was written by	the data were analyzed by	Analyzed the data	Formal analysis	YES
5775218	29379516	WJ	4	The experiments were performed by|the data were analyzed by|The manuscript was written by	The manuscript was written by	Wrote the paper	Writing - Original Draft	YES
5775218	29379516	WL	4	This research was designed by|the data were analyzed by|The manuscript was written by	This research was designed by	Conceived and designed the experiments	-	YES
5775218	29379516	WL	4	This research was designed by|the data were analyzed by|The manuscript was written by	the data were analyzed by	Analyzed the data	Formal analysis	YES
5775218	29379516	WL	4	This research was designed by|the data were analyzed by|The manuscript was written by	The manuscript was written by	Wrote the paper	Writing - Original Draft	YES
5775218	29379516	YW	4	The experiments were performed by	The experiments were performed by	Performed the experiments	Investigation	YES
5775218	29379516	ZC	4	The experiments were performed by	The experiments were performed by	Performed the experiments	Investigation	YES
5399014	28429330	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5399014	28429330	HRS	PLoS52	analyzed the results	analyzed the results	Analyzed the data	Formal analysis	YES
5399014	28429330	JH	PLoS52	analyzed the results	analyzed the results	Analyzed the data	Formal analysis	YES
5399014	28429330	MS	PLoS52	analyzed the results|drafted the manuscript	analyzed the results	Analyzed the data	Formal analysis	YES
5399014	28429330	MS	PLoS52	analyzed the results|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5399014	28429330	The authors	PLoS52	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5399014	28429330	WS	PLoS52	designed the experiments|performed the experiments|analyzed the results|drafted the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5399014	28429330	WS	PLoS52	designed the experiments|performed the experiments|analyzed the results|drafted the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5399014	28429330	WS	PLoS52	designed the experiments|performed the experiments|analyzed the results|drafted the manuscript	analyzed the results	Analyzed the data	Formal analysis	YES
5399014	28429330	WS	PLoS52	designed the experiments|performed the experiments|analyzed the results|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5399014	28429330	XZ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5399014	28429330	YS	PLoS52	designed the experiments|drafted the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5399014	28429330	YS	PLoS52	designed the experiments|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5691835	29145809	ISN	2	designed and participated in all the experiments and assisted in improving the technical sites of the project	designed and participated in all the experiments and assisted in improving the technical sites of the project	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5691835	29145809	JIP	2	perform in silico analysis	perform in silico analysis	Performed the experiments	Formal analysis|Investigation	YES
5691835	29145809	MAK	2	carried out the computational analysis, plant culture and sample preparation, performed rt pcr and real time pcr, analyzed the data and drafted the manuscript	carried out the computational analysis, plant culture and sample preparation, performed rt pcr and real time pcr, analyzed the data and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5691835	29145809	MKB	2	perform in silico analysis	perform in silico analysis	Performed the experiments	Formal analysis|Investigation	YES
5691835	29145809	UKN	2	revised the manuscript and made necessary corrections for giving its final shape	revised the manuscript and made necessary corrections for giving its final shape	Wrote the paper	Writing - Review & Editing	YES
5581924	28878590	AK	2	developed the study protocol|performed the research|carried out the statistical analysis and wrote the manuscript	developed the study protocol	Conceived and designed the experiments	Methodology	YES
5581924	28878590	AK	2	developed the study protocol|performed the research|carried out the statistical analysis and wrote the manuscript	performed the research	Performed the experiments	Investigation	YES
5581924	28878590	AK	2	developed the study protocol|performed the research|carried out the statistical analysis and wrote the manuscript	carried out the statistical analysis and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5581924	28878590	HI	2	developed the study protocol	developed the study protocol	Conceived and designed the experiments	Methodology	YES
5581924	28878590	HM-U	2	carried out the statistical analysis and wrote the manuscript	carried out the statistical analysis and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5581924	28878590	MM	2	developed the study protocol|performed the research	developed the study protocol	Conceived and designed the experiments	Methodology	YES
5581924	28878590	MM	2	developed the study protocol|performed the research	performed the research	Performed the experiments	Investigation	YES
5581924	28878590	MS	2	performed the research	performed the research	Performed the experiments	Investigation	YES
5581924	28878590	NO	2	developed the study protocol|carried out the statistical analysis and wrote the manuscript	developed the study protocol	Conceived and designed the experiments	Methodology	YES
5581924	28878590	NO	2	developed the study protocol|carried out the statistical analysis and wrote the manuscript	carried out the statistical analysis and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5581924	28878590	RI	2	performed the research	performed the research	Performed the experiments	Investigation	YES
5581924	28878590	TI	2	developed the study protocol	developed the study protocol	Conceived and designed the experiments	Methodology	YES
5581924	28878590	TT	2	developed the study protocol|was the project leader of this study|performed the research|carried out the statistical analysis and wrote the manuscript	developed the study protocol	Conceived and designed the experiments	Methodology	YES
5581924	28878590	TT	2	developed the study protocol|was the project leader of this study|performed the research|carried out the statistical analysis and wrote the manuscript	was the project leader of this study	-	Supervision	YES
5581924	28878590	TT	2	developed the study protocol|was the project leader of this study|performed the research|carried out the statistical analysis and wrote the manuscript	performed the research	Performed the experiments	Investigation	YES
5581924	28878590	TT	2	developed the study protocol|was the project leader of this study|performed the research|carried out the statistical analysis and wrote the manuscript	carried out the statistical analysis and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5581924	28878590	YS	2	performed the research	performed the research	Performed the experiments	Investigation	YES
5167344	27815315	AGV	2	assisted with the conducted experiments with	assisted with the conducted experiments with	Performed the experiments	Investigation	YES
5167344	27815315	AM	2	provided key reagents	provided key reagents	Contributed reagents/materials/analysis tools	Resources	YES
5167344	27815315	CRS	2	designed experiments, analysed data and wrote the manuscript|supervised the project	designed experiments, analysed data and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5167344	27815315	CRS	2	designed experiments, analysed data and wrote the manuscript|supervised the project	supervised the project	-	Supervision	YES
5167344	27815315	NCR	2	assisted with the conducted experiments with	assisted with the conducted experiments with	Performed the experiments	Investigation	YES
5167344	27815315	PVM	2	designed experiments, analysed data and wrote the manuscript|conducted experiments with	designed experiments, analysed data and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5167344	27815315	PVM	2	designed experiments, analysed data and wrote the manuscript|conducted experiments with	conducted experiments with	Performed the experiments	Investigation	YES
5167344	27815315	SD	2	assisted with the conducted experiments with	assisted with the conducted experiments with	Performed the experiments	Investigation	YES
1942085	17712416	CW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1942085	17712416	LP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1942085	17712416	LP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1942085	17712416	LP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1942085	17712416	LP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1942085	17712416	LP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1942085	17712416	NP	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1942085	17712416	NP	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1942085	17712416	NP	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1942085	17712416	RH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1942085	17712416	RH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1942085	17712416	RH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5399015	28429329	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5399015	28429329	GN	2	contribution was supervision, critical and data interpretation, paper review, and corrections	contribution was supervision, critical and data interpretation, paper review, and corrections	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Supervision|Writing - Review & Editing	YES
5399015	28429329	HH	2	did paper review	did paper review	-	-	NO
5399015	28429329	MGF	2	did the experimental design, laboratory work, data analysis, development of the code in matlab, modeling, and paper writing	did the experimental design, laboratory work, data analysis, development of the code in matlab, modeling, and paper writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Software|Writing - Original Draft	YES
5399015	28429329	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5693578	29149845	CM	PLoS5	Performed the experiment|Analysed and interpreted microarray and qpcr data|Revised and edited the paper	Performed the experiment	Performed the experiments	Investigation	YES
5693578	29149845	CM	PLoS5	Performed the experiment|Analysed and interpreted microarray and qpcr data|Revised and edited the paper	Analysed and interpreted microarray and qpcr data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5693578	29149845	CM	PLoS5	Performed the experiment|Analysed and interpreted microarray and qpcr data|Revised and edited the paper	Revised and edited the paper	Wrote the paper	Writing - Review & Editing	YES
5693578	29149845	DRT	PLoS5	Conceived and designed the experiments|Wrote the paper|Revised and edited the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5693578	29149845	DRT	PLoS5	Conceived and designed the experiments|Wrote the paper|Revised and edited the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5693578	29149845	DRT	PLoS5	Conceived and designed the experiments|Wrote the paper|Revised and edited the paper	Revised and edited the paper	Wrote the paper	Writing - Review & Editing	YES
5693578	29149845	HM	PLoS5	Conceived and designed the experiments|Revised and edited the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5693578	29149845	HM	PLoS5	Conceived and designed the experiments|Revised and edited the paper	Revised and edited the paper	Wrote the paper	Writing - Review & Editing	YES
5693578	29149845	JFT	PLoS5	Conceived and designed the experiments|Performed the experiment|Revised and edited the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5693578	29149845	JFT	PLoS5	Conceived and designed the experiments|Performed the experiment|Revised and edited the paper	Performed the experiment	Performed the experiments	Investigation	YES
5693578	29149845	JFT	PLoS5	Conceived and designed the experiments|Performed the experiment|Revised and edited the paper	Revised and edited the paper	Wrote the paper	Writing - Review & Editing	YES
5693578	29149845	KHS	PLoS5	Analysed and interpreted dna methylation data|Wrote the paper|Revised and edited the paper	Analysed and interpreted dna methylation data	Analyzed the data	Formal analysis	YES
5693578	29149845	KHS	PLoS5	Analysed and interpreted dna methylation data|Wrote the paper|Revised and edited the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5693578	29149845	KHS	PLoS5	Analysed and interpreted dna methylation data|Wrote the paper|Revised and edited the paper	Revised and edited the paper	Wrote the paper	Writing - Review & Editing	YES
5693578	29149845	LMV	PLoS5	Performed the experiment|Analysed and interpreted microarray and qpcr data|Wrote the paper|Revised and edited the paper	Performed the experiment	Performed the experiments	Investigation	YES
5693578	29149845	LMV	PLoS5	Performed the experiment|Analysed and interpreted microarray and qpcr data|Wrote the paper|Revised and edited the paper	Analysed and interpreted microarray and qpcr data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5693578	29149845	LMV	PLoS5	Performed the experiment|Analysed and interpreted microarray and qpcr data|Wrote the paper|Revised and edited the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5693578	29149845	LMV	PLoS5	Performed the experiment|Analysed and interpreted microarray and qpcr data|Wrote the paper|Revised and edited the paper	Revised and edited the paper	Wrote the paper	Writing - Review & Editing	YES
5693578	29149845	MC	PLoS5	Performed the experiment|Revised and edited the paper	Performed the experiment	Performed the experiments	Investigation	YES
5693578	29149845	MC	PLoS5	Performed the experiment|Revised and edited the paper	Revised and edited the paper	Wrote the paper	Writing - Review & Editing	YES
4416008	25928545	BB	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416008	25928545	BB	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4416008	25928545	BB	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416008	25928545	HT	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4416008	25928545	HT	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416008	25928545	JF	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416008	25928545	JF	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416008	25928545	JF	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416008	25928545	JF	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416008	25928545	JS	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416008	25928545	SH	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4416008	25928545	SH	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416008	25928545	TDT	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416008	25928545	TDT	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416008	25928545	TDT	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416008	25928545	TDT	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416008	25928545	TT	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416008	25928545	TT	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4416008	25928545	TT	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5775269	29379515	AR	2	analyzed the data and revised the final version	analyzed the data and revised the final version	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5775269	29379515	All authors	2	listed have made substantial contributions to the work	listed have made substantial contributions to the work	-	-	NO
5775269	29379515	CV	2	analyzed the data and revised the final version	analyzed the data and revised the final version	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5775269	29379515	FC	2	collaborated in sampling and molecular investigations	collaborated in sampling and molecular investigations	Performed the experiments	Investigation	YES
5775269	29379515	FG	2	designed the study, wrote the manuscript, analyzed the data, and supervised the project	designed the study, wrote the manuscript, analyzed the data, and supervised the project	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Supervision|Writing - Original Draft	YES
5775269	29379515	GC	2	analyzed the data and revised the final version	analyzed the data and revised the final version	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5775269	29379515	IR	2	designed the study, wrote the manuscript, analyzed the data, and supervised the project	designed the study, wrote the manuscript, analyzed the data, and supervised the project	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Supervision|Writing - Original Draft	YES
5775269	29379515	LC	2	collaborated in sampling and molecular investigations	collaborated in sampling and molecular investigations	Performed the experiments	Investigation	YES
5775269	29379515	OP	2	analyzed the data and revised the final version	analyzed the data and revised the final version	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5775269	29379515	PP	2	designed the study, wrote the manuscript, analyzed the data, and supervised the project	designed the study, wrote the manuscript, analyzed the data, and supervised the project	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Supervision|Writing - Original Draft	YES
5775269	29379515	SA	2	collaborated in sampling and molecular investigations	collaborated in sampling and molecular investigations	Performed the experiments	Investigation	YES
5775269	29379515	SP	2	analyzed the data and revised the final version	analyzed the data and revised the final version	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5775269	29379515	SR	2	designed the study, wrote the manuscript, analyzed the data, and supervised the project	designed the study, wrote the manuscript, analyzed the data, and supervised the project	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Supervision|Writing - Original Draft	YES
1942086	17712405	PU	1	Conceived the idea, developed the model, contributed to all versions of the paper	Conceived the idea, developed the model, contributed to all versions of the paper	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
1942086	17712405	RW	1	Contributed to identifying the problem and developing the idea, critically evaluated the model and the data, contributed to all versions of the paper	Contributed to identifying the problem and developing the idea, critically evaluated the model and the data, contributed to all versions of the paper	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Investigation|Methodology|Resources|Writing - Original Draft	YES
5167347	27799150	AV	2	designed the experiments and interpreted the data	designed the experiments and interpreted the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5167347	27799150	DAC	2	generated and characterized the hela scc1 gfp cell line	generated and characterized the hela scc1 gfp cell line	Performed the experiments	Investigation	YES
5167347	27799150	DG	2	designed the experiments and interpreted the data|generated reagents	designed the experiments and interpreted the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5167347	27799150	DG	2	designed the experiments and interpreted the data|generated reagents	generated reagents	Performed the experiments	Investigation	YES
5167347	27799150	DNA	2	loading assays	loading assays	Performed the experiments	Investigation	YES
5167347	27799150	FU	2	designed the experiments and interpreted the data	designed the experiments and interpreted the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5167347	27799150	FW	2	generated reagents	generated reagents	Performed the experiments	Investigation	YES
5167347	27799150	GL	2	generated reagents	generated reagents	Performed the experiments	Investigation	YES
5167347	27799150	IFD	2	designed the experiments and interpreted the data|generated reagents|performed most of the single-molecule imaging experiments and the xenopus experiments|carried out the halo-tmr ctcf single-molecule imaging|performed the single-molecule imaging described in fig 2|wrote the manuscript	designed the experiments and interpreted the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5167347	27799150	IFD	2	designed the experiments and interpreted the data|generated reagents|performed most of the single-molecule imaging experiments and the xenopus experiments|carried out the halo-tmr ctcf single-molecule imaging|performed the single-molecule imaging described in fig 2|wrote the manuscript	generated reagents	Performed the experiments	Investigation	YES
5167347	27799150	IFD	2	designed the experiments and interpreted the data|generated reagents|performed most of the single-molecule imaging experiments and the xenopus experiments|carried out the halo-tmr ctcf single-molecule imaging|performed the single-molecule imaging described in fig 2|wrote the manuscript	performed most of the single-molecule imaging experiments and the xenopus experiments	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
5167347	27799150	IFD	2	designed the experiments and interpreted the data|generated reagents|performed most of the single-molecule imaging experiments and the xenopus experiments|carried out the halo-tmr ctcf single-molecule imaging|performed the single-molecule imaging described in fig 2|wrote the manuscript	carried out the halo-tmr ctcf single-molecule imaging	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
5167347	27799150	IFD	2	designed the experiments and interpreted the data|generated reagents|performed most of the single-molecule imaging experiments and the xenopus experiments|carried out the halo-tmr ctcf single-molecule imaging|performed the single-molecule imaging described in fig 2|wrote the manuscript	performed the single-molecule imaging described in fig 2	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
5167347	27799150	IFD	2	designed the experiments and interpreted the data|generated reagents|performed most of the single-molecule imaging experiments and the xenopus experiments|carried out the halo-tmr ctcf single-molecule imaging|performed the single-molecule imaging described in fig 2|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5167347	27799150	J-MP	2	designed the experiments and interpreted the data|wrote the manuscript	designed the experiments and interpreted the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5167347	27799150	J-MP	2	designed the experiments and interpreted the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5167347	27799150	MIM	2	designed the experiments and interpreted the data|performed the single-molecule imaging described in fig 2	designed the experiments and interpreted the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5167347	27799150	MIM	2	designed the experiments and interpreted the data|performed the single-molecule imaging described in fig 2	performed the single-molecule imaging described in fig 2	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
5167347	27799150	MO-H	2	designed the experiments and interpreted the data	designed the experiments and interpreted the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5167347	27799150	MPZ	2	designed the experiments and interpreted the data|generated reagents|performed the halo-tmr ctcf electrophoretic mobility shift assays and the tetr halo-tmr single-molecule imaging|carried out the halo-tmr ctcf single-molecule imaging	designed the experiments and interpreted the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5167347	27799150	MPZ	2	designed the experiments and interpreted the data|generated reagents|performed the halo-tmr ctcf electrophoretic mobility shift assays and the tetr halo-tmr single-molecule imaging|carried out the halo-tmr ctcf single-molecule imaging	generated reagents	Performed the experiments	Investigation	YES
5167347	27799150	MPZ	2	designed the experiments and interpreted the data|generated reagents|performed the halo-tmr ctcf electrophoretic mobility shift assays and the tetr halo-tmr single-molecule imaging|carried out the halo-tmr ctcf single-molecule imaging	performed the halo-tmr ctcf electrophoretic mobility shift assays and the tetr halo-tmr single-molecule imaging	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
5167347	27799150	MPZ	2	designed the experiments and interpreted the data|generated reagents|performed the halo-tmr ctcf electrophoretic mobility shift assays and the tetr halo-tmr single-molecule imaging|carried out the halo-tmr ctcf single-molecule imaging	carried out the halo-tmr ctcf single-molecule imaging	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
5167347	27799150	PJHV	2	designed the experiments and interpreted the data|generated reagents	designed the experiments and interpreted the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5167347	27799150	PJHV	2	designed the experiments and interpreted the data|generated reagents	generated reagents	Performed the experiments	Investigation	YES
5167347	27799150	RL	2	designed the experiments and interpreted the data	designed the experiments and interpreted the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5403781	28439850	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5403781	28439850	CL	2	assisted in the experimental design and the interpretation of data, and reviewed the manuscript	assisted in the experimental design and the interpretation of data, and reviewed the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Review & Editing	YES
5403781	28439850	RF	2	coordinated the study and reviewed the manuscript	coordinated the study and reviewed the manuscript	Wrote the paper	Project administration|Writing - Review & Editing	YES
5403781	28439850	Richard Twyman	2	for his assistance with editing the manuscript	for his assistance with editing the manuscript	Wrote the paper	Writing - Review & Editing	YES
5403781	28439850	SE	2	designed and carried out the experiments, analyzed the results and wrote the manuscript	designed and carried out the experiments, analyzed the results and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5403781	28439850	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5403781	28439850	UC	2	coordinated the study and reviewed the manuscript	coordinated the study and reviewed the manuscript	Wrote the paper	Project administration|Writing - Review & Editing	YES
4416009	25927995	IF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416009	25927995	IF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416009	25927995	IF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416009	25927995	IF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416009	25927995	IF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416009	25927995	LG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416009	25927995	LG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416009	25927995	LG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416009	25927995	LG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416009	25927995	LG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416009	25927995	LL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416009	25927995	LL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416009	25927995	LL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416009	25927995	LL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5775275	29379512	DG	2	performed modeling	performed modeling	Performed the experiments	Investigation|Methodology	YES
5775275	29379512	HX	2	performed molecular cloning, expression, and biochemical analysis of wheat asparagine synthetases	performed molecular cloning, expression, and biochemical analysis of wheat asparagine synthetases	Performed the experiments	Investigation	YES
5775275	29379512	MH	2	performed modeling	performed modeling	Performed the experiments	Investigation|Methodology	YES
5775275	29379512	RG	2	performed nucleotide sequence analysis of wheat asparagine synthetases	performed nucleotide sequence analysis of wheat asparagine synthetases	Performed the experiments	Investigation	YES
5775275	29379512	SP	2	performed statistical analyses	performed statistical analyses	Analyzed the data	Formal analysis	YES
5775275	29379512	SR	2	performed genomic analyses	performed genomic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5775275	29379512	TC	2	performed modeling	performed modeling	Performed the experiments	Investigation|Methodology	YES
5596463	28919843	All authors	2	reviewed and approved the final manuscript	reviewed and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5596463	28919843	CS	2	were involved in data intervention, helped draft the manuscript, and provided significant advice	were involved in data intervention, helped draft the manuscript, and provided significant advice	Wrote the paper	Writing - Original Draft	YES
5596463	28919843	KU	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5596463	28919843	MY	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5596463	28919843	SF	2	designed the study|supervised preparation of the manuscript|his students were involved in data acquisition and intervention	designed the study	Conceived and designed the experiments	Methodology	YES
5596463	28919843	SF	2	designed the study|supervised preparation of the manuscript|his students were involved in data acquisition and intervention	supervised preparation of the manuscript	Wrote the paper	Supervision|Writing - Original Draft	YES
5596463	28919843	SF	2	designed the study|supervised preparation of the manuscript|his students were involved in data acquisition and intervention	his students were involved in data acquisition and intervention	Performed the experiments	Investigation	YES
5596463	28919843	SI	2	were involved in data intervention, helped draft the manuscript, and provided significant advice	were involved in data intervention, helped draft the manuscript, and provided significant advice	Wrote the paper	Writing - Original Draft	YES
5596463	28919843	TH	2	acted as the study physician and was involved in data acquisition	acted as the study physician and was involved in data acquisition	Performed the experiments	Investigation	YES
1942115	17712402	AJ	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1942115	17712402	BB	PLoS5	Wrote the paper|Enrolled volunteers	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1942115	17712402	BB	PLoS5	Wrote the paper|Enrolled volunteers	Enrolled volunteers	Performed the experiments	Investigation	YES
1942115	17712402	BS	PLoS5	Wrote the paper|Enrolled volunteers	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1942115	17712402	BS	PLoS5	Wrote the paper|Enrolled volunteers	Enrolled volunteers	Performed the experiments	Investigation	YES
1942115	17712402	CD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Project manager of this multi-centric trial	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1942115	17712402	CD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Project manager of this multi-centric trial	Analyzed the data	Analyzed the data	Formal analysis	YES
1942115	17712402	CD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Project manager of this multi-centric trial	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1942115	17712402	CD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Project manager of this multi-centric trial	Project manager of this multi-centric trial	-	Project administration	YES
1942115	17712402	CG	PLoS5	Contributed to the pharmaceutical organization and planning of the study drug	Contributed to the pharmaceutical organization and planning of the study drug	Conceived and designed the experiments	Methodology|Project administration	YES
1942115	17712402	DS	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1942115	17712402	GG	PLoS5	Wrote the paper|Enrolled volunteers	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1942115	17712402	GG	PLoS5	Wrote the paper|Enrolled volunteers	Enrolled volunteers	Performed the experiments	Investigation	YES
1942115	17712402	GP	PLoS5	Conceived and designed the experiments|Analyzed the data|Enrolled volunteers	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1942115	17712402	GP	PLoS5	Conceived and designed the experiments|Analyzed the data|Enrolled volunteers	Analyzed the data	Analyzed the data	Formal analysis	YES
1942115	17712402	GP	PLoS5	Conceived and designed the experiments|Analyzed the data|Enrolled volunteers	Enrolled volunteers	Performed the experiments	Investigation	YES
1942115	17712402	HG	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1942115	17712402	IB	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1942115	17712402	IB	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1942115	17712402	IP	PLoS5	Wrote the paper|Enrolled volunteers	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1942115	17712402	IP	PLoS5	Wrote the paper|Enrolled volunteers	Enrolled volunteers	Performed the experiments	Investigation	YES
1942115	17712402	JC	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1942115	17712402	JC	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1942115	17712402	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1942115	17712402	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1942115	17712402	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1942115	17712402	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1942115	17712402	LC	PLoS5	Wrote the paper|Enrolled volunteers	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1942115	17712402	LC	PLoS5	Wrote the paper|Enrolled volunteers	Enrolled volunteers	Performed the experiments	Investigation	YES
1942115	17712402	MS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1942115	17712402	NB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1942115	17712402	OL	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Enrolled volunteers	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1942115	17712402	OL	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Enrolled volunteers	Performed the experiments	Performed the experiments	Investigation	YES
1942115	17712402	OL	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Enrolled volunteers	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1942115	17712402	OL	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Enrolled volunteers	Enrolled volunteers	Performed the experiments	Investigation	YES
1942115	17712402	SF	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
6253717	30568784	All authors	2	discussed the results and commented on the manuscript	discussed the results and commented on the manuscript	-	-	NO
6253717	30568784	C.P.	2	synthesized and characterized the electrochemical catalysts and performed the catalytic reactivity	synthesized and characterized the electrochemical catalysts and performed the catalytic reactivity	Performed the experiments	Investigation	YES
6253717	30568784	E.M.Z.	2	performed the mossbauer	performed the mossbauer	Performed the experiments	Investigation	YES
6253717	30568784	H.G.	2	designed the research|discussed the results and commented on the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
6253717	30568784	H.G.	2	designed the research|discussed the results and commented on the manuscript	discussed the results and commented on the manuscript	-	-	NO
6253717	30568784	K.M.	2	designed the research|discussed the results and commented on the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
6253717	30568784	K.M.	2	designed the research|discussed the results and commented on the manuscript	discussed the results and commented on the manuscript	-	-	NO
6253717	30568784	M.D.	2	designed the research|discussed the results and commented on the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
6253717	30568784	M.D.	2	designed the research|discussed the results and commented on the manuscript	discussed the results and commented on the manuscript	-	-	NO
6253717	30568784	M.E.M.	2	performed the mossbauer	performed the mossbauer	Performed the experiments	Investigation	YES
6253717	30568784	M.H.	2	performed the xafs measurement and analyzed the exafs and xanes data|performed dft simulations	performed the xafs measurement and analyzed the exafs and xanes data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6253717	30568784	M.H.	2	performed the xafs measurement and analyzed the exafs and xanes data|performed dft simulations	performed dft simulations	Performed the experiments	Formal analysis|Investigation	YES
6253717	30568784	N.A.K.	2	performed xps measurements	performed xps measurements	Performed the experiments	Investigation	YES
6253717	30568784	P.W.M.	2	designed the research|synthesized and characterized the electrochemical catalysts and performed the catalytic reactivity	designed the research	Conceived and designed the experiments	Methodology	YES
6253717	30568784	P.W.M.	2	designed the research|synthesized and characterized the electrochemical catalysts and performed the catalytic reactivity	synthesized and characterized the electrochemical catalysts and performed the catalytic reactivity	Performed the experiments	Investigation	YES
6253717	30568784	S.M.	2	performed the xafs measurement and analyzed the exafs and xanes data|performed dft simulations	performed the xafs measurement and analyzed the exafs and xanes data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6253717	30568784	S.M.	2	performed the xafs measurement and analyzed the exafs and xanes data|performed dft simulations	performed dft simulations	Performed the experiments	Formal analysis|Investigation	YES
6253717	30568784	S.Y.	2	designed the research|performed the synthesis and characterization of compounds 2-4|solved the x-ray crystal structures	designed the research	Conceived and designed the experiments	Methodology	YES
6253717	30568784	S.Y.	2	designed the research|performed the synthesis and characterization of compounds 2-4|solved the x-ray crystal structures	performed the synthesis and characterization of compounds 2-4	Performed the experiments	Investigation	YES
6253717	30568784	S.Y.	2	designed the research|performed the synthesis and characterization of compounds 2-4|solved the x-ray crystal structures	solved the x-ray crystal structures	-	-	NO
6253717	30568784	SQUID	2	epr measurements and analyzed the data	epr measurements and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6253717	30568784	T.S.	2	performed dft simulations	performed dft simulations	Performed the experiments	Formal analysis|Investigation	YES
6253717	30568784	V.F.	2	performed the synthesis and characterization of compounds 2-4	performed the synthesis and characterization of compounds 2-4	Performed the experiments	Investigation	YES
5697016	29157201	AK	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|contributed to the writing of the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5697016	29157201	AK	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|contributed to the writing of the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5697016	29157201	AK	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|contributed to the writing of the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5697016	29157201	AK	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|contributed to the writing of the manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5697016	29157201	AL	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|contributed to the writing of the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5697016	29157201	AL	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|contributed to the writing of the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5697016	29157201	AL	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|contributed to the writing of the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5697016	29157201	AL	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|contributed to the writing of the manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5697016	29157201	CRB	PLoS52	conceived and designed the experiments|analyzed the data|contributed to the writing of the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5697016	29157201	CRB	PLoS52	conceived and designed the experiments|analyzed the data|contributed to the writing of the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5697016	29157201	CRB	PLoS52	conceived and designed the experiments|analyzed the data|contributed to the writing of the manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5697016	29157201	GM	PLoS52	contributed to the writing of the manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5697016	29157201	RMT	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|contributed to the writing of the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5697016	29157201	RMT	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|contributed to the writing of the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5697016	29157201	RMT	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|contributed to the writing of the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5697016	29157201	RMT	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|contributed to the writing of the manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5697016	29157201	The authors	PLoS52	have read, and approved this manuscript	have read, and approved this manuscript	-	-	NO
5210087	27875245	BS	2	conceived the study, wrote the manuscript and secured funding	conceived the study, wrote the manuscript and secured funding	Conceived and designed the experiments|Wrote the paper	Conceptualization|Funding acquisition|Writing - Original Draft	YES
5210087	27875245	CJH	2	provided reagents and expert advice	provided reagents and expert advice	Contributed reagents/materials/analysis tools	Resources	YES
5210087	27875245	CRW	2	provided reagents and expert advice	provided reagents and expert advice	Contributed reagents/materials/analysis tools	Resources	YES
5210087	27875245	HA	2	performed the bioinformatic analysis of the rna seq data	performed the bioinformatic analysis of the rna seq data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5210087	27875245	MV	2	performed experiments, analysed data and wrote the manuscript	performed experiments, analysed data and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5210087	27875245	RB	2	provided reagents and expert advice	provided reagents and expert advice	Contributed reagents/materials/analysis tools	Resources	YES
4628698	26557718	Gregor J. Jenny	2	contributed equivalently to the paper	contributed equivalently to the paper	-	-	NO
4628698	26557718	Rebecca Brauchli	2	contributed equivalently to the paper	contributed equivalently to the paper	-	-	NO
3871918	24381515	Hsin-Hua Chou	2	have equal contributions to this paper and will be the cofirst authors	have equal contributions to this paper and will be the cofirst authors	-	-	NO
3871918	24381515	Tien-Yu Wu	2	have equal contributions to this paper and will be the cofirst authors	have equal contributions to this paper and will be the cofirst authors	-	-	NO
4416010	25927987	BM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416010	25927987	BM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416010	25927987	BM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416010	25927987	BS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4416010	25927987	BS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416010	25927987	FH	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4416010	25927987	FH	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416010	25927987	GM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416010	25927987	GM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416010	25927987	GM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416010	25927987	MF-W	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416010	25927987	MF-W	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416010	25927987	MF-W	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416010	25927987	NL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416010	25927987	NL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416010	25927987	NL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416010	25927987	NL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416010	25927987	WW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416010	25927987	WW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416010	25927987	WW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5407406	28452041	All authors	2	discussed the results and edited the final manuscript|read and approved the final manuscript	discussed the results and edited the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5407406	28452041	All authors	2	discussed the results and edited the final manuscript|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5407406	28452041	DAB	2	contributed with materials and analysis tools, and participated in the design of the substrate profiling	contributed with materials and analysis tools, and participated in the design of the substrate profiling	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5407406	28452041	DVR	2	conceived the experiments, participated in the design and coordination of the work and wrote most of the manuscript	conceived the experiments, participated in the design and coordination of the work and wrote most of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Project administration|Writing - Original Draft	YES
5407406	28452041	GC	2	data analysis and helped to draft the manuscript	data analysis and helped to draft the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5407406	28452041	MDM	2	contributed with materials, analysis tools, and strains for reference biotransformations	contributed with materials, analysis tools, and strains for reference biotransformations	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5407406	28452041	MJF	2	contributed to gc data collection and analysis	contributed to gc data collection and analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5407406	28452041	RDC	2	performed the bioinformatic and experimental work	performed the bioinformatic and experimental work	Performed the experiments	Formal analysis|Investigation	YES
1942116	17712408	AT	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1942116	17712408	AT	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1942116	17712408	CM	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1942116	17712408	CM	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1942116	17712408	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1942116	17712408	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1942116	17712408	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1942116	17712408	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1942116	17712408	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1942116	17712408	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1942116	17712408	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1942116	17712408	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1942116	17712408	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1942116	17712408	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5775296	29379510	CC	PLoS52	performed the experiments|contributed toward the data analyses|wrote and revised the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5775296	29379510	CC	PLoS52	performed the experiments|contributed toward the data analyses|wrote and revised the manuscript	contributed toward the data analyses	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5775296	29379510	CC	PLoS52	performed the experiments|contributed toward the data analyses|wrote and revised the manuscript	wrote and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5775296	29379510	DY	PLoS52	contributed toward the data analyses	contributed toward the data analyses	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5775296	29379510	FS	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5775296	29379510	HJ	PLoS52	conceived the idea, acquired funding and designed the experiments|wrote and revised the manuscript	conceived the idea, acquired funding and designed the experiments	Conceived and designed the experiments	Conceptualization|Funding acquisition|Methodology	YES
5775296	29379510	HJ	PLoS52	conceived the idea, acquired funding and designed the experiments|wrote and revised the manuscript	wrote and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5775296	29379510	LP	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5775296	29379510	QL	PLoS52	conceived the idea, acquired funding and designed the experiments|wrote and revised the manuscript	conceived the idea, acquired funding and designed the experiments	Conceived and designed the experiments	Conceptualization|Funding acquisition|Methodology	YES
5775296	29379510	QL	PLoS52	conceived the idea, acquired funding and designed the experiments|wrote and revised the manuscript	wrote and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5775296	29379510	SY	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5775296	29379510	YC	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5775296	29379510	YD	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5697113	29162034	ER	PLoS52	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5697113	29162034	IC	PLoS52	provided material|conducted the experiment|conceived and designed the whole experiment|revised the manuscript	provided material	Contributed reagents/materials/analysis tools	Resources	YES
5697113	29162034	IC	PLoS52	provided material|conducted the experiment|conceived and designed the whole experiment|revised the manuscript	conducted the experiment	Performed the experiments	Investigation	YES
5697113	29162034	IC	PLoS52	provided material|conducted the experiment|conceived and designed the whole experiment|revised the manuscript	conceived and designed the whole experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5697113	29162034	IC	PLoS52	provided material|conducted the experiment|conceived and designed the whole experiment|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5697113	29162034	MC	PLoS52	conducted the experiment|analyzed the data|drafted the manuscript	conducted the experiment	Performed the experiments	Investigation	YES
5697113	29162034	MC	PLoS52	conducted the experiment|analyzed the data|drafted the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5697113	29162034	MC	PLoS52	conducted the experiment|analyzed the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5697113	29162034	MEC	PLoS52	provided material|conceived and designed the whole experiment|revised the manuscript	provided material	Contributed reagents/materials/analysis tools	Resources	YES
5697113	29162034	MEC	PLoS52	provided material|conceived and designed the whole experiment|revised the manuscript	conceived and designed the whole experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5697113	29162034	MEC	PLoS52	provided material|conceived and designed the whole experiment|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5697113	29162034	MM	PLoS52	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5697113	29162034	MMA	PLoS52	analyzed the data|conceived and designed the whole experiment|revised the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5697113	29162034	MMA	PLoS52	analyzed the data|conceived and designed the whole experiment|revised the manuscript	conceived and designed the whole experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5697113	29162034	MMA	PLoS52	analyzed the data|conceived and designed the whole experiment|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5697113	29162034	TC	PLoS52	analyzed the data|revised the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5697113	29162034	TC	PLoS52	analyzed the data|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5697113	29162034	TLN	PLoS52	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5697113	29162034	VC	PLoS52	provided material|conducted the experiment|conceived and designed the whole experiment|revised the manuscript	provided material	Contributed reagents/materials/analysis tools	Resources	YES
5697113	29162034	VC	PLoS52	provided material|conducted the experiment|conceived and designed the whole experiment|revised the manuscript	conducted the experiment	Performed the experiments	Investigation	YES
5697113	29162034	VC	PLoS52	provided material|conducted the experiment|conceived and designed the whole experiment|revised the manuscript	conceived and designed the whole experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5697113	29162034	VC	PLoS52	provided material|conducted the experiment|conceived and designed the whole experiment|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4628699	26557716	In-Bog Lee	2	contributed equally to this work	contributed equally to this work	-	-	NO
4628699	26557716	Jin-Young Kim	2	contributed equally to this work	contributed equally to this work	-	-	NO
6032025	29968514	NF	2	was responsible for data collection, especially accessing russian-language sources	was responsible for data collection, especially accessing russian-language sources	Performed the experiments	Investigation	YES
6032025	29968514	PB	2	were responsible for data analysis, writing and editing of the manuscript	were responsible for data analysis, writing and editing of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
6032025	29968514	SC	2	were responsible for data analysis, writing and editing of the manuscript	were responsible for data analysis, writing and editing of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
6032025	29968514	TKY	2	was responsible for study design, data collection/analysis, writing and editing	was responsible for study design, data collection/analysis, writing and editing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Review & Editing	YES
5596471	28919842	All other authors	2	reviewed, suggested edits, and approved the final manuscript	reviewed, suggested edits, and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5596471	28919842	BJS	2	completed an initial review and provided significant edits and additional content before review and approval of other authors	completed an initial review and provided significant edits and additional content before review and approval of other authors	Wrote the paper	Writing - Review & Editing	YES
5596471	28919842	CMK	2	prepared and compiled the draft for initial review and incorporated all suggested edits into the final draft	prepared and compiled the draft for initial review and incorporated all suggested edits into the final draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5596471	28919842	JRS	2	completed an initial review and provided significant edits and additional content before review and approval of other authors	completed an initial review and provided significant edits and additional content before review and approval of other authors	Wrote the paper	Writing - Review & Editing	YES
5596471	28919842	SMA	2	completed an initial review and provided significant edits and additional content before review and approval of other authors	completed an initial review and provided significant edits and additional content before review and approval of other authors	Wrote the paper	Writing - Review & Editing	YES
4375366	25780238	A.D.S.	5	conducted the fieldwork and the song analysis|conducted the statistical analyses|wrote the paper with input from M	conducted the fieldwork and the song analysis	Performed the experiments	Investigation	YES
4375366	25780238	A.D.S.	5	conducted the fieldwork and the song analysis|conducted the statistical analyses|wrote the paper with input from M	conducted the statistical analyses	Analyzed the data	Formal analysis	YES
4375366	25780238	A.D.S.	5	conducted the fieldwork and the song analysis|conducted the statistical analyses|wrote the paper with input from M	wrote the paper with input from M	Wrote the paper	Writing - Original Draft	YES
4375366	25780238	B.K.	5	designed the study|wrote the paper with input from M	designed the study	Conceived and designed the experiments	Methodology	YES
4375366	25780238	B.K.	5	designed the study|wrote the paper with input from M	wrote the paper with input from M	Wrote the paper	Writing - Original Draft	YES
4375366	25780238	M.V.	5	conducted the statistical analyses	conducted the statistical analyses	Analyzed the data	Formal analysis	YES
5239998	27932447	LK	2	discussed and performed the experiments and analysed the data	discussed and performed the experiments and analysed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5239998	27932447	MDN	2	discussed and performed the experiments and analysed the data	discussed and performed the experiments and analysed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5239998	27932447	OK	2	discussed and performed the experiments and analysed the data	discussed and performed the experiments and analysed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5239998	27932447	SM	2	designed the project|discussed and performed the experiments and analysed the data|wrote the manuscript with the inputs from all other authors	designed the project	Conceived and designed the experiments	Methodology	YES
5239998	27932447	SM	2	designed the project|discussed and performed the experiments and analysed the data|wrote the manuscript with the inputs from all other authors	discussed and performed the experiments and analysed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5239998	27932447	SM	2	designed the project|discussed and performed the experiments and analysed the data|wrote the manuscript with the inputs from all other authors	wrote the manuscript with the inputs from all other authors	Wrote the paper	Writing - Original Draft	YES
5239998	27932447	VA	2	discussed and performed the experiments and analysed the data	discussed and performed the experiments and analysed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5239998	27932447	YV	2	discussed and performed the experiments and analysed the data	discussed and performed the experiments and analysed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
1942117	17712419	BH	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1942117	17712419	FL	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1942117	17712419	LW	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1942117	17712419	MB	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1942117	17712419	OS	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1942117	17712419	OS	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1942117	17712419	SH	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1942117	17712419	SO	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1942117	17712419	SO	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1942117	17712419	YK	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1942117	17712419	YK	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1942117	17712419	YZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1942117	17712419	YZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1942117	17712419	YZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1942117	17712419	YZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5407408	28452040	All	2	data are shown in figures and tables	data are shown in figures and tables	-	Visualization	YES
5407408	28452040	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5407408	28452040	FL	2	planned and carried out the experiments, analyzed the data and wrote the manuscript	planned and carried out the experiments, analyzed the data and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
5407408	28452040	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5407408	28452040	XZ	2	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5407408	28452040	YH	2	assisted to carry out experiments	assisted to carry out experiments	Performed the experiments	Investigation	YES
5407408	28452040	ZW	2	participated in the data analysis and finalized the manuscript	participated in the data analysis and finalized the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4416011	25927983	BMB	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416011	25927983	BMB	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416011	25927983	MMV	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416011	25927983	MMV	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416011	25927983	MMV	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5697147	29157209	CH	2	helped to carry out the data analysis and participated in the drafted manuscript	helped to carry out the data analysis and participated in the drafted manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5697147	29157209	DPX	2	conceived the experiments and performed the experiment|carried out the data analysis and wrote the paper	conceived the experiments and performed the experiment	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5697147	29157209	DPX	2	conceived the experiments and performed the experiment|carried out the data analysis and wrote the paper	carried out the data analysis and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5697147	29157209	GXW	2	helped to carry out the data analysis and participated in the drafted manuscript	helped to carry out the data analysis and participated in the drafted manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5697147	29157209	GYP	2	conceived the experiments and performed the experiment|helped to carry out the data analysis and participated in the drafted manuscript	conceived the experiments and performed the experiment	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5697147	29157209	GYP	2	conceived the experiments and performed the experiment|helped to carry out the data analysis and participated in the drafted manuscript	helped to carry out the data analysis and participated in the drafted manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5697147	29157209	JYP	2	helped to carry out the data analysis and participated in the drafted manuscript	helped to carry out the data analysis and participated in the drafted manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5697147	29157209	ZXK	2	conceived the experiments and performed the experiment|carried out the data analysis and wrote the paper	conceived the experiments and performed the experiment	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5697147	29157209	ZXK	2	conceived the experiments and performed the experiment|carried out the data analysis and wrote the paper	carried out the data analysis and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5697147	29157209	ZYH	2	conceived the experiments and performed the experiment	conceived the experiments and performed the experiment	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5776104	29387072	AC	2	did the bioinformatic analysis	did the bioinformatic analysis	-	Formal analysis	YES
5776104	29387072	All the authors	2	approved the final version of this text	approved the final version of this text	-	-	NO
5776104	29387072	DS	2	provided the metabolic data	provided the metabolic data	Contributed reagents/materials/analysis tools	Resources	YES
5776104	29387072	EC	2	did the bioinformatic analysis	did the bioinformatic analysis	-	Formal analysis	YES
5776104	29387072	FE	2	designed the project|developed the taqman array tool|took part in data interpretation|revised it critically	designed the project	Conceived and designed the experiments	Methodology	YES
5776104	29387072	FE	2	designed the project|developed the taqman array tool|took part in data interpretation|revised it critically	developed the taqman array tool	Performed the experiments	Investigation	YES
5776104	29387072	FE	2	designed the project|developed the taqman array tool|took part in data interpretation|revised it critically	took part in data interpretation	Analyzed the data	Formal analysis	YES
5776104	29387072	FE	2	designed the project|developed the taqman array tool|took part in data interpretation|revised it critically	revised it critically	Wrote the paper	Writing - Review & Editing	YES
5776104	29387072	LC	2	took part in data interpretation|revised it critically	took part in data interpretation	Analyzed the data	Formal analysis	YES
5776104	29387072	LC	2	took part in data interpretation|revised it critically	revised it critically	Wrote the paper	Writing - Review & Editing	YES
5776104	29387072	LDC	2	took part in data interpretation|drafted the work	took part in data interpretation	Analyzed the data	Formal analysis	YES
5776104	29387072	LDC	2	took part in data interpretation|drafted the work	drafted the work	Wrote the paper	Writing - Original Draft	YES
5776104	29387072	MM	2	took part in data interpretation	took part in data interpretation	Analyzed the data	Formal analysis	YES
5776104	29387072	MSG	2	designed the project|took part in data interpretation|revised it critically	designed the project	Conceived and designed the experiments	Methodology	YES
5776104	29387072	MSG	2	designed the project|took part in data interpretation|revised it critically	took part in data interpretation	Analyzed the data	Formal analysis	YES
5776104	29387072	MSG	2	designed the project|took part in data interpretation|revised it critically	revised it critically	Wrote the paper	Writing - Review & Editing	YES
5776104	29387072	MT	2	to management and characterization of plant materials at morphological and transcriptional level|took part in data interpretation	to management and characterization of plant materials at morphological and transcriptional level	Performed the experiments	Investigation	YES
5776104	29387072	MT	2	to management and characterization of plant materials at morphological and transcriptional level|took part in data interpretation	took part in data interpretation	Analyzed the data	Formal analysis	YES
5776104	29387072	PM-S	2	genotyped the fem aromatic core collection and prepared the samples for metabolic analysis|took part in data interpretation	genotyped the fem aromatic core collection and prepared the samples for metabolic analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5776104	29387072	PM-S	2	genotyped the fem aromatic core collection and prepared the samples for metabolic analysis|took part in data interpretation	took part in data interpretation	Analyzed the data	Formal analysis	YES
5776104	29387072	RL	2	provided the metabolic data	provided the metabolic data	Contributed reagents/materials/analysis tools	Resources	YES
5776104	29387072	SL	2	developed the taqman array tool|genotyped the fem aromatic core collection and prepared the samples for metabolic analysis	developed the taqman array tool	Performed the experiments	Investigation	YES
5776104	29387072	SL	2	developed the taqman array tool|genotyped the fem aromatic core collection and prepared the samples for metabolic analysis	genotyped the fem aromatic core collection and prepared the samples for metabolic analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5776104	29387072	SM	2	provided the metabolic data	provided the metabolic data	Contributed reagents/materials/analysis tools	Resources	YES
5596842	28919844	JTD	2	came up with the idea for the manuscript|wrote the article	came up with the idea for the manuscript	Conceived and designed the experiments	Conceptualization	YES
5596842	28919844	JTD	2	came up with the idea for the manuscript|wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
5596842	28919844	MKR	2	wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
5596842	28919844	MR	2	edited the article and provided valuable comments to enhance the review	edited the article and provided valuable comments to enhance the review	Wrote the paper	Writing - Review & Editing	YES
1942118	17712430	AV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1942118	17712430	AV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1942118	17712430	AV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1942118	17712430	AV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1942118	17712430	AV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1942118	17712430	JR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1942118	17712430	JR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1942118	17712430	JR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1942118	17712430	JR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1942118	17712430	JR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1942118	17712430	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1942118	17712430	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1942118	17712430	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1942118	17712430	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1942118	17712430	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1942118	17712430	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1942118	17712430	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1942118	17712430	KY	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1942118	17712430	KY	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1942118	17712430	MP	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1942118	17712430	MP	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1942118	17712430	RG	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1942118	17712430	RG	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5286356	27979921	AS	2	performed the research|performed x-ray diffraction experiments and analyzed x-ray data|wrote the manuscript	performed the research	Performed the experiments	Investigation	YES
5286356	27979921	AS	2	performed the research|performed x-ray diffraction experiments and analyzed x-ray data|wrote the manuscript	performed x-ray diffraction experiments and analyzed x-ray data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5286356	27979921	AS	2	performed the research|performed x-ray diffraction experiments and analyzed x-ray data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5286356	27979921	EY	2	performed the research|performed x-ray diffraction experiments and analyzed x-ray data	performed the research	Performed the experiments	Investigation	YES
5286356	27979921	EY	2	performed the research|performed x-ray diffraction experiments and analyzed x-ray data	performed x-ray diffraction experiments and analyzed x-ray data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5286356	27979921	JB	2	performed the research|performed x-ray diffraction experiments and analyzed x-ray data	performed the research	Performed the experiments	Investigation	YES
5286356	27979921	JB	2	performed the research|performed x-ray diffraction experiments and analyzed x-ray data	performed x-ray diffraction experiments and analyzed x-ray data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5286356	27979921	JK	2	performed the research|carried out molecular dynamics simulations	performed the research	Performed the experiments	Investigation	YES
5286356	27979921	JK	2	performed the research|carried out molecular dynamics simulations	carried out molecular dynamics simulations	Performed the experiments	Formal analysis|Investigation	YES
5286356	27979921	KS-I	2	designed the research|performed the research|performed protein purification and crystallization experiments|performed x-ray diffraction experiments and analyzed x-ray data|wrote the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
5286356	27979921	KS-I	2	designed the research|performed the research|performed protein purification and crystallization experiments|performed x-ray diffraction experiments and analyzed x-ray data|wrote the manuscript	performed the research	Performed the experiments	Investigation	YES
5286356	27979921	KS-I	2	designed the research|performed the research|performed protein purification and crystallization experiments|performed x-ray diffraction experiments and analyzed x-ray data|wrote the manuscript	performed protein purification and crystallization experiments	Performed the experiments	Investigation	YES
5286356	27979921	KS-I	2	designed the research|performed the research|performed protein purification and crystallization experiments|performed x-ray diffraction experiments and analyzed x-ray data|wrote the manuscript	performed x-ray diffraction experiments and analyzed x-ray data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5286356	27979921	KS-I	2	designed the research|performed the research|performed protein purification and crystallization experiments|performed x-ray diffraction experiments and analyzed x-ray data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5286356	27979921	MT	2	performed the research|carried out molecular dynamics simulations|wrote the manuscript	performed the research	Performed the experiments	Investigation	YES
5286356	27979921	MT	2	performed the research|carried out molecular dynamics simulations|wrote the manuscript	carried out molecular dynamics simulations	Performed the experiments	Formal analysis|Investigation	YES
5286356	27979921	MT	2	performed the research|carried out molecular dynamics simulations|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5286356	27979921	SA	2	performed the research|performed protein purification and crystallization experiments|performed x-ray diffraction experiments and analyzed x-ray data	performed the research	Performed the experiments	Investigation	YES
5286356	27979921	SA	2	performed the research|performed protein purification and crystallization experiments|performed x-ray diffraction experiments and analyzed x-ray data	performed protein purification and crystallization experiments	Performed the experiments	Investigation	YES
5286356	27979921	SA	2	performed the research|performed protein purification and crystallization experiments|performed x-ray diffraction experiments and analyzed x-ray data	performed x-ray diffraction experiments and analyzed x-ray data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5286356	27979921	SS	2	performed the research|performed protein purification and crystallization experiments|performed x-ray diffraction experiments and analyzed x-ray data|wrote the manuscript	performed the research	Performed the experiments	Investigation	YES
5286356	27979921	SS	2	performed the research|performed protein purification and crystallization experiments|performed x-ray diffraction experiments and analyzed x-ray data|wrote the manuscript	performed protein purification and crystallization experiments	Performed the experiments	Investigation	YES
5286356	27979921	SS	2	performed the research|performed protein purification and crystallization experiments|performed x-ray diffraction experiments and analyzed x-ray data|wrote the manuscript	performed x-ray diffraction experiments and analyzed x-ray data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5286356	27979921	SS	2	performed the research|performed protein purification and crystallization experiments|performed x-ray diffraction experiments and analyzed x-ray data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5286356	27979921	SY	2	designed the research|performed the research|wrote the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
5286356	27979921	SY	2	designed the research|performed the research|wrote the manuscript	performed the research	Performed the experiments	Investigation	YES
5286356	27979921	SY	2	designed the research|performed the research|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5286356	27979921	TT	2	designed the research|performed the research|performed x-ray diffraction experiments and analyzed x-ray data|wrote the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
5286356	27979921	TT	2	designed the research|performed the research|performed x-ray diffraction experiments and analyzed x-ray data|wrote the manuscript	performed the research	Performed the experiments	Investigation	YES
5286356	27979921	TT	2	designed the research|performed the research|performed x-ray diffraction experiments and analyzed x-ray data|wrote the manuscript	performed x-ray diffraction experiments and analyzed x-ray data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5286356	27979921	TT	2	designed the research|performed the research|performed x-ray diffraction experiments and analyzed x-ray data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5286356	27979921	all authors	2	discussed and commented on the results and the manuscript	discussed and commented on the results and the manuscript	-	-	NO
4416012	25928892	ADA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416012	25928892	ADA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416012	25928892	ADA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416012	25928892	DKW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416012	25928892	DKW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416012	25928892	DKW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416012	25928892	DL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416012	25928892	DL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416012	25928892	DL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416012	25928892	JL	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4416012	25928892	JL	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416012	25928892	MS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4416012	25928892	MS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4375371	25780243	All authors	2	contributed to drafting and revising the paper	contributed to drafting and revising the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4375371	25780243	D.C.	2	designed and built the experiment and collected field data	designed and built the experiment and collected field data	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4375371	25780243	J.B.	2	designed and coordinated, the study system|designed and built the experiment and collected field data|contributed to the analysis of data	designed and coordinated, the study system	Conceived and designed the experiments	Methodology|Project administration	YES
4375371	25780243	J.B.	2	designed and coordinated, the study system|designed and built the experiment and collected field data|contributed to the analysis of data	designed and built the experiment and collected field data	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4375371	25780243	J.B.	2	designed and coordinated, the study system|designed and built the experiment and collected field data|contributed to the analysis of data	contributed to the analysis of data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
4375371	25780243	K.J.G.	2	designed and coordinated, the study system	designed and coordinated, the study system	Conceived and designed the experiments	Methodology|Project administration	YES
4375371	25780243	R.I.	2	contributed to the analysis of data	contributed to the analysis of data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
4375371	25780243	T.W.D.	2	designed and coordinated, the study system|designed and built the experiment and collected field data|contributed to the analysis of data	designed and coordinated, the study system	Conceived and designed the experiments	Methodology|Project administration	YES
4375371	25780243	T.W.D.	2	designed and coordinated, the study system|designed and built the experiment and collected field data|contributed to the analysis of data	designed and built the experiment and collected field data	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4375371	25780243	T.W.D.	2	designed and coordinated, the study system|designed and built the experiment and collected field data|contributed to the analysis of data	contributed to the analysis of data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5422223	28484998	All	2	data are fully available without restriction	data are fully available without restriction	-	-	NO
5422223	28484998	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5422223	28484998	CC	2	conceived of the study, designed the experiments, and helped to draft the manuscript	conceived of the study, designed the experiments, and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
5422223	28484998	GQL	2	conceived of the study, designed the experiments, and helped to draft the manuscript	conceived of the study, designed the experiments, and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
5422223	28484998	JFZ	2	helped to perform the experiments and the modeling analysis	helped to perform the experiments and the modeling analysis	Performed the experiments	Investigation|Methodology	YES
5422223	28484998	JYF	2	performed the experiments, created the graphs, and drafted this manuscript	performed the experiments, created the graphs, and drafted this manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5422223	28484998	JYZ	2	helped to perform the experiments and the modeling analysis	helped to perform the experiments and the modeling analysis	Performed the experiments	Investigation|Methodology	YES
5422223	28484998	RHZ	2	participated in the design of the study	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
5422223	28484998	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5422223	28484998	YFH	2	helped to perform the experiments and the modeling analysis	helped to perform the experiments and the modeling analysis	Performed the experiments	Investigation|Methodology	YES
5776106	29387070	All authors	2	provided final approval of the manuscript to be published	provided final approval of the manuscript to be published	-	-	NO
5776106	29387070	GK	2	provided substantial contributions to the conception and design of the study, as well as interpretation of data and in writing the manuscript	provided substantial contributions to the conception and design of the study, as well as interpretation of data and in writing the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Methodology|Resources|Writing - Original Draft	YES
5776106	29387070	JS	2	provided substantial contributions to the conception and design of the study, as well as interpretation of data and in writing the manuscript	provided substantial contributions to the conception and design of the study, as well as interpretation of data and in writing the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Methodology|Resources|Writing - Original Draft	YES
5776106	29387070	KM	2	substantially contributed to the intellectual content of the manuscript through multiple edits as well as providing regular supervision of ss throughout all experiments	substantially contributed to the intellectual content of the manuscript through multiple edits as well as providing regular supervision of ss throughout all experiments	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Review & Editing	YES
5776106	29387070	PL	2	substantially contributed to the intellectual content of the manuscript through multiple edits as well as providing regular supervision of ss throughout all experiments	substantially contributed to the intellectual content of the manuscript through multiple edits as well as providing regular supervision of ss throughout all experiments	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Review & Editing	YES
5776106	29387070	SS	2	designed and built the experimental aquarium set up, ran all experiments, processed samples, conducted data analysis and drafted the manuscript	designed and built the experimental aquarium set up, ran all experiments, processed samples, conducted data analysis and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
1942119	17712409	CM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1942119	17712409	CM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1942119	17712409	CM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1942119	17712409	JP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1942119	17712409	JP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1942119	17712409	JP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1942119	17712409	JP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1942119	17712409	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1942119	17712409	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1942119	17712409	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1942119	17712409	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1942119	17712409	JT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1942119	17712409	JT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1942119	17712409	JT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1942119	17712409	JT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1942119	17712409	YP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1942119	17712409	YP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1942119	17712409	YP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1942119	17712409	YP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5697406	29157198	KY	2	interpreted the data|wrote the manuscript	interpreted the data	Analyzed the data	Formal analysis	YES
5697406	29157198	KY	2	interpreted the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5697406	29157198	MP	2	interpreted the data|wrote the manuscript	interpreted the data	Analyzed the data	Formal analysis	YES
5697406	29157198	MP	2	interpreted the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5697406	29157198	RZ	2	designed the study|analyzed data|interpreted the data|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5697406	29157198	RZ	2	designed the study|analyzed data|interpreted the data|wrote the manuscript	analyzed data	Analyzed the data	Formal analysis	YES
5697406	29157198	RZ	2	designed the study|analyzed data|interpreted the data|wrote the manuscript	interpreted the data	Analyzed the data	Formal analysis	YES
5697406	29157198	RZ	2	designed the study|analyzed data|interpreted the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5697406	29157198	YW	2	designed the study|analyzed data|interpreted the data|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5697406	29157198	YW	2	designed the study|analyzed data|interpreted the data|wrote the manuscript	analyzed data	Analyzed the data	Formal analysis	YES
5697406	29157198	YW	2	designed the study|analyzed data|interpreted the data|wrote the manuscript	interpreted the data	Analyzed the data	Formal analysis	YES
5697406	29157198	YW	2	designed the study|analyzed data|interpreted the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5697406	29157198	ZG	2	designed the study|interpreted the data|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5697406	29157198	ZG	2	designed the study|interpreted the data|wrote the manuscript	interpreted the data	Analyzed the data	Formal analysis	YES
5697406	29157198	ZG	2	designed the study|interpreted the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5598028	28924423	DR	2	is the sole author for this manuscript, and conceptualised, wrote and edited the article	is the sole author for this manuscript, and conceptualised, wrote and edited the article	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
5423876	28488255	Both authors	2	designed and conducted the experiments and evaluated the results|read and approved the final manuscript	designed and conducted the experiments and evaluated the results	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5423876	28488255	Both authors	2	designed and conducted the experiments and evaluated the results|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5423876	28488255	GN	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5423876	28488255	KT	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4416013	25928140	DMS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416013	25928140	DMS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4416013	25928140	DMS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4416013	25928140	DMS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416013	25928140	DW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416013	25928140	DW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416013	25928140	DW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416013	25928140	DW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416013	25928140	DW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416013	25928140	KH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416013	25928140	KH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416013	25928140	KH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416013	25928140	KH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416013	25928140	KH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416013	25928140	KW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416013	25928140	KW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416013	25928140	KW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416013	25928140	KW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416013	25928140	KW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416013	25928140	OHD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416013	25928140	OHD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416013	25928140	OHD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416013	25928140	OHD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416013	25928140	OHD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416013	25928140	RH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416013	25928140	RH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4416013	25928140	RH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4416013	25928140	RH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5286366	28028052	AE	2	conceived the experiments and wrote the manuscript	conceived the experiments and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5286366	28028052	AK	2	carried out the emgfp-tm1-i co-immunoprecipitation assays	carried out the emgfp-tm1-i co-immunoprecipitation assays	Performed the experiments	Investigation	YES
5286366	28028052	IG	2	conceived the experiments and wrote the manuscript|carried out the rest of the experiments and data analysis	conceived the experiments and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5286366	28028052	IG	2	conceived the experiments and wrote the manuscript|carried out the rest of the experiments and data analysis	carried out the rest of the experiments and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5286366	28028052	VS	2	carried out qrt-pcr analysis of mrnas immunoprecipitated under stringent conditions	carried out qrt-pcr analysis of mrnas immunoprecipitated under stringent conditions	Performed the experiments	Investigation	YES
3872104	24385872	All authors	2	contributed markedly to the paper, discussed the results, and commented on the paper	contributed markedly to the paper, discussed the results, and commented on the paper	-	-	NO
3872104	24385872	Dhandapani Thangamani	2	participated in the acquisition and analysis of data	participated in the acquisition and analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3872104	24385872	Ivan Ogheneochuko Edafiogho	2	participated in the conception and design of the study and synthesis of e139	participated in the conception and design of the study and synthesis of e139	Conceived and designed the experiments	Conceptualization|Methodology	YES
3872104	24385872	Willias Masocha	2	participated in the conception and design of the study, acquisition and analysis of data, statistical analysis, project supervision, and drafting and preparation of the paper	participated in the conception and design of the study, acquisition and analysis of data, statistical analysis, project supervision, and drafting and preparation of the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Supervision|Writing - Original Draft	YES
1942120	17712410	HB	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1942120	17712410	HB	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1942120	17712410	HM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1942120	17712410	HM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1942120	17712410	HS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1942120	17712410	HS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1942120	17712410	HS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1942120	17712410	JP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1942120	17712410	JP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1942120	17712410	JP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1942120	17712410	JP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1942120	17712410	JP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1942120	17712410	OG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1942120	17712410	OG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1942120	17712410	OJ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1942120	17712410	OJ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1942120	17712410	SK	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1942120	17712410	SK	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1942120	17712410	SW	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1942120	17712410	SW	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5609049	28947895	AGE	2	has supervised over the research|have both design the research|have both analyzed the qualitative data|have contributed equally to the manuscript	has supervised over the research	-	Supervision	YES
5609049	28947895	AGE	2	has supervised over the research|have both design the research|have both analyzed the qualitative data|have contributed equally to the manuscript	have both design the research	Conceived and designed the experiments	Methodology	YES
5609049	28947895	AGE	2	has supervised over the research|have both design the research|have both analyzed the qualitative data|have contributed equally to the manuscript	have both analyzed the qualitative data	Analyzed the data	Formal analysis	YES
5609049	28947895	AGE	2	has supervised over the research|have both design the research|have both analyzed the qualitative data|have contributed equally to the manuscript	have contributed equally to the manuscript	-	-	NO
5609049	28947895	ID	2	have both design the research|conducted the interviews and transcript|have both analyzed the qualitative data|have contributed equally to the manuscript	have both design the research	Conceived and designed the experiments	Methodology	YES
5609049	28947895	ID	2	have both design the research|conducted the interviews and transcript|have both analyzed the qualitative data|have contributed equally to the manuscript	conducted the interviews and transcript	Performed the experiments	Investigation	YES
5609049	28947895	ID	2	have both design the research|conducted the interviews and transcript|have both analyzed the qualitative data|have contributed equally to the manuscript	have both analyzed the qualitative data	Analyzed the data	Formal analysis	YES
5609049	28947895	ID	2	have both design the research|conducted the interviews and transcript|have both analyzed the qualitative data|have contributed equally to the manuscript	have contributed equally to the manuscript	-	-	NO
5776114	29387071	AD	2	have made an equal substantial, direct and intellectual contribution to writing the review and its revision, and approved it for publication	have made an equal substantial, direct and intellectual contribution to writing the review and its revision, and approved it for publication	Wrote the paper	Writing - Review & Editing	YES
5776114	29387071	Both authors	2	have made an equal substantial, direct and intellectual contribution to writing the review and its revision, and approved it for publication	have made an equal substantial, direct and intellectual contribution to writing the review and its revision, and approved it for publication	Wrote the paper	Writing - Review & Editing	YES
5776114	29387071	H. The	2	authors complied to the ethical standards	authors complied to the ethical standards	-	-	NO
5776114	29387071	RH	2	have made an equal substantial, direct and intellectual contribution to writing the review and its revision, and approved it for publication	have made an equal substantial, direct and intellectual contribution to writing the review and its revision, and approved it for publication	Wrote the paper	Writing - Review & Editing	YES
5425655	28497287	All authors	2	made substantial contributions to the experimental design, interpretation of the results and revisions of the manuscript|read and approved the final manuscript	made substantial contributions to the experimental design, interpretation of the results and revisions of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Review & Editing	YES
5425655	28497287	All authors	2	made substantial contributions to the experimental design, interpretation of the results and revisions of the manuscript|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5425655	28497287	EB	2	wrote the manuscript and performed parts of lab work	wrote the manuscript and performed parts of lab work	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5425655	28497287	JR	2	performed most lab work	performed most lab work	Performed the experiments	Investigation	YES
5425655	28497287	The authors	2	declare that they have no competing of interests	declare that they have no competing of interests	-	-	NO
5697431	29157197	AS	2	conceived the experimental design|conducted the sperm motility assay|provided substantial suggestions on interpretation of the data sets and critically read and helped finalize the manuscript	conceived the experimental design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5697431	29157197	AS	2	conceived the experimental design|conducted the sperm motility assay|provided substantial suggestions on interpretation of the data sets and critically read and helped finalize the manuscript	conducted the sperm motility assay	Performed the experiments	Investigation	YES
5697431	29157197	AS	2	conceived the experimental design|conducted the sperm motility assay|provided substantial suggestions on interpretation of the data sets and critically read and helped finalize the manuscript	provided substantial suggestions on interpretation of the data sets and critically read and helped finalize the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
5697431	29157197	DK	2	organized and performed the rna preparation	organized and performed the rna preparation	Performed the experiments	Investigation	YES
5697431	29157197	JMW	2	conceived the experimental design|provided substantial suggestions on interpretation of the data sets and critically read and helped finalize the manuscript	conceived the experimental design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5697431	29157197	JMW	2	conceived the experimental design|provided substantial suggestions on interpretation of the data sets and critically read and helped finalize the manuscript	provided substantial suggestions on interpretation of the data sets and critically read and helped finalize the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
5697431	29157197	JS	2	conceived the experimental design|provided substantial suggestions on interpretation of the data sets and critically read and helped finalize the manuscript	conceived the experimental design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5697431	29157197	JS	2	conceived the experimental design|provided substantial suggestions on interpretation of the data sets and critically read and helped finalize the manuscript	provided substantial suggestions on interpretation of the data sets and critically read and helped finalize the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
5697431	29157197	ML	2	conducted the animal breeding and line selection and provided substantial section on the manuscript	conducted the animal breeding and line selection and provided substantial section on the manuscript	Performed the experiments	Investigation	YES
5697431	29157197	MM	2	conceived the experimental design|conducted the sperm motility assay|conducted the statistical evaluation of microarray data and the qpcr re-analysis, interpreted the results and drafted the manuscript	conceived the experimental design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5697431	29157197	MM	2	conceived the experimental design|conducted the sperm motility assay|conducted the statistical evaluation of microarray data and the qpcr re-analysis, interpreted the results and drafted the manuscript	conducted the sperm motility assay	Performed the experiments	Investigation	YES
5697431	29157197	MM	2	conceived the experimental design|conducted the sperm motility assay|conducted the statistical evaluation of microarray data and the qpcr re-analysis, interpreted the results and drafted the manuscript	conducted the statistical evaluation of microarray data and the qpcr re-analysis, interpreted the results and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5697431	29157197	NR	2	conducted the animal breeding and line selection and provided substantial section on the manuscript	conducted the animal breeding and line selection and provided substantial section on the manuscript	Performed the experiments	Investigation	YES
5697431	29157197	RNA	2	labeling and rna microarray hybridization and worked on evaluation of the transcriptional data and provided substantial sections on the manuscript	labeling and rna microarray hybridization and worked on evaluation of the transcriptional data and provided substantial sections on the manuscript	Performed the experiments	Investigation	YES
5286369	27836995	All authors	PLoS52	contributed to writing and editing the manuscript	contributed to writing and editing the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5286369	27836995	DLG	PLoS52	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5286369	27836995	DT	PLoS52	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5286369	27836995	GK	PLoS52	analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
5286369	27836995	IP	PLoS52	analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
5286369	27836995	JJT	PLoS52	designed the experiments|performed the experimental work|analysed the data	designed the experiments	Conceived and designed the experiments	Methodology	YES
5286369	27836995	JJT	PLoS52	designed the experiments|performed the experimental work|analysed the data	performed the experimental work	Performed the experiments	Investigation	YES
5286369	27836995	JJT	PLoS52	designed the experiments|performed the experimental work|analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
5286369	27836995	KWL	PLoS52	performed the experimental work	performed the experimental work	Performed the experiments	Investigation	YES
5286369	27836995	NPD	PLoS52	analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
5286369	27836995	SAW	PLoS52	performed the experimental work	performed the experimental work	Performed the experiments	Investigation	YES
5286369	27836995	SPM	PLoS52	performed the experimental work	performed the experimental work	Performed the experiments	Investigation	YES
5286369	27836995	TGA	PLoS52	analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
4416014	25927435	HY	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416014	25927435	JS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416014	25927435	JS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416014	25927435	JS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416014	25927435	JS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416014	25927435	PL	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416014	25927435	PL	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416014	25927435	ST	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416014	25927435	ST	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416014	25927435	ST	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416014	25927435	XL	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416014	25927435	YG	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5615454	28959158	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5615454	28959158	CSM	2	assisted with experimental procedures, data acquisition, and manuscript editing	assisted with experimental procedures, data acquisition, and manuscript editing	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5615454	28959158	CTH	2	was, in part, responsible for conception and design of the experiment, assisted with experimental procedures, data acquisition and manuscript editing	was, in part, responsible for conception and design of the experiment, assisted with experimental procedures, data acquisition and manuscript editing	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Writing - Review & Editing	YES
5615454	28959158	DDP	2	assisted with experimental procedures, data acquisition, and manuscript editing	assisted with experimental procedures, data acquisition, and manuscript editing	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5615454	28959158	JMD	2	assisted with experimental procedures, data acquisition, and manuscript editing	assisted with experimental procedures, data acquisition, and manuscript editing	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5615454	28959158	JSM	2	procured funding for the study, was, in part, responsible for the conception and design of the experiment, assisted with experimental procedures and data acquisition, and was primarily responsible for writing of the manuscript	procured funding for the study, was, in part, responsible for the conception and design of the experiment, assisted with experimental procedures and data acquisition, and was primarily responsible for writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Funding acquisition|Investigation|Methodology|Writing - Original Draft	YES
5615454	28959158	KCY	2	assisted with experimental procedures, data acquisition, and manuscript editing	assisted with experimental procedures, data acquisition, and manuscript editing	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5615454	28959158	MDR	2	procured funding for the study, was, in part, responsible for the conception and design of the experiment, and assisted with experimental procedures, data acquisition, and manuscript editing	procured funding for the study, was, in part, responsible for the conception and design of the experiment, and assisted with experimental procedures, data acquisition, and manuscript editing	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Funding acquisition|Investigation|Methodology|Writing - Review & Editing	YES
5615454	28959158	MJL	2	assisted with experimental procedures, data acquisition, and manuscript editing	assisted with experimental procedures, data acquisition, and manuscript editing	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5615454	28959158	MPF	2	assisted with experimental procedures, data acquisition, and manuscript editing	assisted with experimental procedures, data acquisition, and manuscript editing	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5615454	28959158	NDMJ	2	was, in part, responsible for the conception and design of the experiment and assisted with experimental procedures, data acquisition, and manuscript editing	was, in part, responsible for the conception and design of the experiment and assisted with experimental procedures, data acquisition, and manuscript editing	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Writing - Review & Editing	YES
5615454	28959158	PAR	2	assisted with experimental procedures, data acquisition and manuscript editing	assisted with experimental procedures, data acquisition and manuscript editing	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5615454	28959158	PWM	2	assisted with experimental procedures, data acquisition, and manuscript editing	assisted with experimental procedures, data acquisition, and manuscript editing	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5615454	28959158	RJC	2	assisted with experimental procedures, data acquisition and manuscript editing	assisted with experimental procedures, data acquisition and manuscript editing	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5615454	28959158	TWDM	2	assisted with experimental procedures, data acquisition, and manuscript editing	assisted with experimental procedures, data acquisition, and manuscript editing	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5427057	28497288	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5427057	28497288	GX	2	participated in some of the experiments	participated in some of the experiments	Performed the experiments	Investigation	YES
5427057	28497288	MB	2	gave advice in the study and edited the manuscript	gave advice in the study and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5427057	28497288	RS	2	coordinated the study and helped in the drafting of the manuscript	coordinated the study and helped in the drafting of the manuscript	Wrote the paper	Project administration|Writing - Original Draft	YES
5427057	28497288	SH	2	designed and conducted the bulk of the experiments, performed analysis and interpretation of data, and drafted the manuscript	designed and conducted the bulk of the experiments, performed analysis and interpretation of data, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5427057	28497288	SM	2	participated in some of the experiments	participated in some of the experiments	Performed the experiments	Investigation	YES
5427057	28497288	TL	2	gave advice in the study and edited the manuscript	gave advice in the study and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5776116	29387079	EM	2	contributed equally to the design and writing of this article	contributed equally to the design and writing of this article	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
5776116	29387079	SF	2	contributed equally to the design and writing of this article	contributed equally to the design and writing of this article	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
1942121	17712422	AD	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1942121	17712422	AF	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1942121	17712422	AO	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1942121	17712422	CP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1942121	17712422	CP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1942121	17712422	CP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1942121	17712422	CP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1942121	17712422	CS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1942121	17712422	CS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1942121	17712422	DB	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1942121	17712422	DB	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1942121	17712422	EM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1942121	17712422	EM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1942121	17712422	EM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1942121	17712422	GS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1942121	17712422	KD	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1942121	17712422	KD	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1942121	17712422	MD	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1942121	17712422	MD	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1942121	17712422	MD	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1942121	17712422	MF	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1942121	17712422	NC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1942121	17712422	NC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1942121	17712422	NC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1942121	17712422	SB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1942121	17712422	VL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5698929	29162033	All authors	2	submitted comments on drafts, and read and approved the final manuscript	submitted comments on drafts, and read and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5698929	29162033	HL	2	led the conception and design of the study and helped write the manuscript	led the conception and design of the study and helped write the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
5698929	29162033	HZ	2	analyzed and interpreted the data, drafted, and wrote the manuscript	analyzed and interpreted the data, drafted, and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5698929	29162033	JQY	2	participated in the interpretation of data	participated in the interpretation of data	Analyzed the data	Formal analysis	YES
5698929	29162033	JR	2	participated in the interpretation of data and helped write the manuscript	participated in the interpretation of data and helped write the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5698929	29162033	LK	2	participated in the interpretation of data	participated in the interpretation of data	Analyzed the data	Formal analysis	YES
5698929	29162033	LLY	2	participated in the interpretation of data	participated in the interpretation of data	Analyzed the data	Formal analysis	YES
5698929	29162033	WN	2	participated in the experiments	participated in the experiments	Performed the experiments	Investigation	YES
5698929	29162033	XYZ	2	participated in the experiments	participated in the experiments	Performed the experiments	Investigation	YES
4628705	26557719	Chiara Frasson	2	are equally contributing authors	are equally contributing authors	-	-	NO
4628705	26557719	Elena Rampazzo	2	are equally contributing authors	are equally contributing authors	-	-	NO
4416015	25928064	DRY	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416015	25928064	DRY	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416015	25928064	DRY	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416015	25928064	EMG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416015	25928064	EMG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416015	25928064	EMG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416015	25928064	EMG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416015	25928064	TTU	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416015	25928064	TTW	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416015	25928064	TTW	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416015	25928064	TTW	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5698953	29162050	DC	2	performed the circrna analysis	performed the circrna analysis	Performed the experiments	Investigation	YES
5698953	29162050	HH	2	wrote the manuscript in consultation with the other authors	wrote the manuscript in consultation with the other authors	Wrote the paper	Writing - Original Draft	YES
5698953	29162050	PM	2	performed the circrna analysis	performed the circrna analysis	Performed the experiments	Investigation	YES
5698953	29162050	VW	2	wrote the manuscript in consultation with the other authors	wrote the manuscript in consultation with the other authors	Wrote the paper	Writing - Original Draft	YES
5331754	28122869	AC	2	designed experiments|designed experiments|analysed data|analysed data	designed experiments	Conceived and designed the experiments	Methodology	YES
5331754	28122869	AC	2	designed experiments|designed experiments|analysed data|analysed data	designed experiments	Conceived and designed the experiments	Methodology	YES
5331754	28122869	AC	2	designed experiments|designed experiments|analysed data|analysed data	analysed data	Analyzed the data	Formal analysis	YES
5331754	28122869	AC	2	designed experiments|designed experiments|analysed data|analysed data	analysed data	Analyzed the data	Formal analysis	YES
5331754	28122869	AK	2	designed experiments|analysed data	designed experiments	Conceived and designed the experiments	Methodology	YES
5331754	28122869	AK	2	designed experiments|analysed data	analysed data	Analyzed the data	Formal analysis	YES
5331754	28122869	BK	2	designed experiments|analysed data	designed experiments	Conceived and designed the experiments	Methodology	YES
5331754	28122869	BK	2	designed experiments|analysed data	analysed data	Analyzed the data	Formal analysis	YES
5331754	28122869	CB	2	performed experiments|analysed data	performed experiments	Performed the experiments	Investigation	YES
5331754	28122869	CB	2	performed experiments|analysed data	analysed data	Analyzed the data	Formal analysis	YES
5331754	28122869	CG	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5331754	28122869	GJT	2	designed experiments|wrote the manuscript|analysed data	designed experiments	Conceived and designed the experiments	Methodology	YES
5331754	28122869	GJT	2	designed experiments|wrote the manuscript|analysed data	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5331754	28122869	GJT	2	designed experiments|wrote the manuscript|analysed data	analysed data	Analyzed the data	Formal analysis	YES
5331754	28122869	GML	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5331754	28122869	JR	2	designed experiments|analysed data	designed experiments	Conceived and designed the experiments	Methodology	YES
5331754	28122869	JR	2	designed experiments|analysed data	analysed data	Analyzed the data	Formal analysis	YES
5331754	28122869	KAS	2	performed experiments|analysed data	performed experiments	Performed the experiments	Investigation	YES
5331754	28122869	KAS	2	performed experiments|analysed data	analysed data	Analyzed the data	Formal analysis	YES
5331754	28122869	MCG	2	designed experiments|performed experiments|analysed data	designed experiments	Conceived and designed the experiments	Methodology	YES
5331754	28122869	MCG	2	designed experiments|performed experiments|analysed data	performed experiments	Performed the experiments	Investigation	YES
5331754	28122869	MCG	2	designed experiments|performed experiments|analysed data	analysed data	Analyzed the data	Formal analysis	YES
5331754	28122869	MN	2	designed experiments|wrote the manuscript|analysed data	designed experiments	Conceived and designed the experiments	Methodology	YES
5331754	28122869	MN	2	designed experiments|wrote the manuscript|analysed data	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5331754	28122869	MN	2	designed experiments|wrote the manuscript|analysed data	analysed data	Analyzed the data	Formal analysis	YES
5331754	28122869	PM	2	designed experiments|wrote the manuscript|performed experiments|analysed data	designed experiments	Conceived and designed the experiments	Methodology	YES
5331754	28122869	PM	2	designed experiments|wrote the manuscript|performed experiments|analysed data	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5331754	28122869	PM	2	designed experiments|wrote the manuscript|performed experiments|analysed data	performed experiments	Performed the experiments	Investigation	YES
5331754	28122869	PM	2	designed experiments|wrote the manuscript|performed experiments|analysed data	analysed data	Analyzed the data	Formal analysis	YES
5331754	28122869	RAMB	2	designed experiments|analysed data	designed experiments	Conceived and designed the experiments	Methodology	YES
5331754	28122869	RAMB	2	designed experiments|analysed data	analysed data	Analyzed the data	Formal analysis	YES
5331754	28122869	RKG	2	designed experiments|wrote the manuscript|analysed data	designed experiments	Conceived and designed the experiments	Methodology	YES
5331754	28122869	RKG	2	designed experiments|wrote the manuscript|analysed data	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5331754	28122869	RKG	2	designed experiments|wrote the manuscript|analysed data	analysed data	Analyzed the data	Formal analysis	YES
5331754	28122869	SAW	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5331754	28122869	SJN	2	designed experiments|analysed data	designed experiments	Conceived and designed the experiments	Methodology	YES
5331754	28122869	SJN	2	designed experiments|analysed data	analysed data	Analyzed the data	Formal analysis	YES
5331754	28122869	SY	2	designed experiments|performed experiments|analysed data	designed experiments	Conceived and designed the experiments	Methodology	YES
5331754	28122869	SY	2	designed experiments|performed experiments|analysed data	performed experiments	Performed the experiments	Investigation	YES
5331754	28122869	SY	2	designed experiments|performed experiments|analysed data	analysed data	Analyzed the data	Formal analysis	YES
5427061	28497290	ASzP	PLoS52	helped to draft manuscript and gave some interpretation on data	helped to draft manuscript and gave some interpretation on data	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5427061	28497290	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5427061	28497290	DD	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5427061	28497290	JMC	PLoS52	participated in the design of the study and carried out the molecular studies, and rna seq data analysis as well as drafted manuscript	participated in the design of the study and carried out the molecular studies, and rna seq data analysis as well as drafted manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5427061	28497290	SC	PLoS52	participated in the design of the study, supervised the work and helped to draft the manuscript	participated in the design of the study, supervised the work and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Original Draft	YES
5776117	29387073	All authors	PLoS52	contributed critically to the drafts and gave final approval for publication	contributed critically to the drafts and gave final approval for publication	Wrote the paper	Writing - Original Draft	YES
5776117	29387073	HL	PLoS52	design the experiments and methodology|wrote the manuscript	design the experiments and methodology	Conceived and designed the experiments|Performed the experiments	Methodology	YES
5776117	29387073	HL	PLoS52	design the experiments and methodology|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5776117	29387073	JW	PLoS52	design the experiments and methodology|wrote the manuscript|analyzed the data	design the experiments and methodology	Conceived and designed the experiments|Performed the experiments	Methodology	YES
5776117	29387073	JW	PLoS52	design the experiments and methodology|wrote the manuscript|analyzed the data	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5776117	29387073	JW	PLoS52	design the experiments and methodology|wrote the manuscript|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5776117	29387073	JZ	PLoS52	conducted the experiments and collected the data	conducted the experiments and collected the data	Performed the experiments	Investigation	YES
5776117	29387073	SZ	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5776117	29387073	YL	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5776117	29387073	YM	PLoS52	design the experiments and methodology|wrote the manuscript|conducted the experiments and collected the data|analyzed the data	design the experiments and methodology	Conceived and designed the experiments|Performed the experiments	Methodology	YES
5776117	29387073	YM	PLoS52	design the experiments and methodology|wrote the manuscript|conducted the experiments and collected the data|analyzed the data	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5776117	29387073	YM	PLoS52	design the experiments and methodology|wrote the manuscript|conducted the experiments and collected the data|analyzed the data	conducted the experiments and collected the data	Performed the experiments	Investigation	YES
5776117	29387073	YM	PLoS52	design the experiments and methodology|wrote the manuscript|conducted the experiments and collected the data|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
1945014	17712427	Cv Av	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1945014	17712427	Od Av	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1945014	17712427	Od Cv	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1945014	17712427	Od Jv	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1945014	17712427	Od Jv Av	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1945014	17712427	Od Jv Av	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1945014	17712427	PT	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5629791	29042830	DB	7	data collection, data analysis manuscript development	data collection, data analysis manuscript development	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5629791	29042830	JS	7	data collection, manuscript development	data collection, manuscript development	Performed the experiments	Investigation	YES
5629791	29042830	LM	7	data collection, data analysis, manuscript development	data collection, data analysis, manuscript development	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5629791	29042830	LWJ	7	data analysis, manuscript development	data analysis, manuscript development	Analyzed the data	Formal analysis	YES
4416016	25927527	CGL	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416016	25927527	CGL	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4416016	25927527	CGL	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416016	25927527	CZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416016	25927527	CZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4416016	25927527	CZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416016	25927527	FH	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416016	25927527	FH	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416016	25927527	FH	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416016	25927527	FH	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416016	25927527	SL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416016	25927527	SL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416016	25927527	SL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416016	25927527	SL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416016	25927527	SMH	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416016	25927527	SMH	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4416016	25927527	SMH	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416016	25927527	TXL	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416016	25927527	TXL	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4416016	25927527	TXL	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416016	25927527	WWX	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416016	25927527	WWX	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416016	25927527	WWX	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416016	25927527	WWX	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416016	25927527	YG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416016	25927527	YG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416016	25927527	YG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416016	25927527	YMT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416016	25927527	YMT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416016	25927527	YMT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416016	25927527	YMT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5331760	28093500	NJB	2	with editing by all authors	with editing by all authors	Wrote the paper	Writing - Review & Editing	YES
5699109	29162049	AMGP	2	performed experiments|drafted the manuscript	performed experiments	Performed the experiments	Investigation	YES
5699109	29162049	AMGP	2	performed experiments|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5699109	29162049	JRB	2	contributed bioinformatic analyses|drafted the manuscript	contributed bioinformatic analyses	Analyzed the data	Formal analysis	YES
5699109	29162049	JRB	2	contributed bioinformatic analyses|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5699109	29162049	MJMB	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5699109	29162049	MRCR	2	contributed bioinformatic analyses	contributed bioinformatic analyses	Analyzed the data	Formal analysis	YES
5699109	29162049	MdB	2	contributed bioinformatic analyses	contributed bioinformatic analyses	Analyzed the data	Formal analysis	YES
5699109	29162049	RW	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5699109	29162049	SM	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5699109	29162049	TKP	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5699109	29162049	VdM	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5699109	29162049	WvS	2	designed the study|drafted the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5699109	29162049	WvS	2	designed the study|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5699109	29162049	XZ	2	performed experiments|designed the study|drafted the manuscript	performed experiments	Performed the experiments	Investigation	YES
5699109	29162049	XZ	2	performed experiments|designed the study|drafted the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5699109	29162049	XZ	2	performed experiments|designed the study|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5776120	29387069	D-YF	7	analyzed and interpreted the data and wrote the article	analyzed and interpreted the data and wrote the article	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5776120	29387069	FG	7	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5776120	29387069	JZ	7	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5776120	29387069	WC	7	analyzed and interpreted the data and wrote the article	analyzed and interpreted the data and wrote the article	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5776120	29387069	WM	7	designed and supervised the experiments|analyzed and interpreted the data and wrote the article	designed and supervised the experiments	Conceived and designed the experiments	Methodology|Supervision	YES
5776120	29387069	WM	7	designed and supervised the experiments|analyzed and interpreted the data and wrote the article	analyzed and interpreted the data and wrote the article	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
1945015	17712420	AB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1945015	17712420	AH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1945015	17712420	AH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1945015	17712420	AH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1945015	17712420	AH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1945015	17712420	CH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1945015	17712420	CH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1945015	17712420	CH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1945015	17712420	CH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1945015	17712420	CH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1945015	17712420	CV	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1945015	17712420	DW	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1945015	17712420	DW	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1945015	17712420	EH	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1945015	17712420	EH	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1945015	17712420	EH	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1945015	17712420	JO	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1945015	17712420	JO	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1945015	17712420	JO	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1945015	17712420	JO	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1945015	17712420	KO	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1945015	17712420	KO	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1945015	17712420	KO	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1945015	17712420	KO	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1945015	17712420	MS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1945015	17712420	MS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1945015	17712420	MS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5427063	28497289	Advanced Talents	PLoS52	of qingdao agricultural university|of qingdao agricultural university	of qingdao agricultural university	-	-	NO
5427063	28497289	Advanced Talents	PLoS52	of qingdao agricultural university|of qingdao agricultural university	of qingdao agricultural university	-	-	NO
5427063	28497289	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5427063	28497289	GW	PLoS52	designed research|performed research|analyzed data|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
5427063	28497289	GW	PLoS52	designed research|performed research|analyzed data|wrote the paper	performed research	Performed the experiments	Investigation	YES
5427063	28497289	GW	PLoS52	designed research|performed research|analyzed data|wrote the paper	analyzed data	Analyzed the data	Formal analysis	YES
5427063	28497289	GW	PLoS52	designed research|performed research|analyzed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5427063	28497289	LG	PLoS52	designed research|performed research|analyzed data|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
5427063	28497289	LG	PLoS52	designed research|performed research|analyzed data|wrote the paper	performed research	Performed the experiments	Investigation	YES
5427063	28497289	LG	PLoS52	designed research|performed research|analyzed data|wrote the paper	analyzed data	Analyzed the data	Formal analysis	YES
5427063	28497289	LG	PLoS52	designed research|performed research|analyzed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5427063	28497289	LL	PLoS52	designed research|performed research|analyzed data|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
5427063	28497289	LL	PLoS52	designed research|performed research|analyzed data|wrote the paper	performed research	Performed the experiments	Investigation	YES
5427063	28497289	LL	PLoS52	designed research|performed research|analyzed data|wrote the paper	analyzed data	Analyzed the data	Formal analysis	YES
5427063	28497289	LL	PLoS52	designed research|performed research|analyzed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5427063	28497289	The authors	PLoS52	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5427063	28497289	WL	PLoS52	contributed new reagents or analytic tools|analyzed data|wrote the paper	contributed new reagents or analytic tools	Contributed reagents/materials/analysis tools	Resources	YES
5427063	28497289	WL	PLoS52	contributed new reagents or analytic tools|analyzed data|wrote the paper	analyzed data	Analyzed the data	Formal analysis	YES
5427063	28497289	WL	PLoS52	contributed new reagents or analytic tools|analyzed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5427063	28497289	ZC	PLoS52	analyzed data|wrote the paper	analyzed data	Analyzed the data	Formal analysis	YES
5427063	28497289	ZC	PLoS52	analyzed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5661918	29093646	AB	3	Conception and design of research|Performed experiments|Approved final version of manuscript	Conception and design of research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5661918	29093646	AB	3	Conception and design of research|Performed experiments|Approved final version of manuscript	Performed experiments	Performed the experiments	Investigation	YES
5661918	29093646	AB	3	Conception and design of research|Performed experiments|Approved final version of manuscript	Approved final version of manuscript	-	-	NO
5661918	29093646	BD	3	Conception and design of research|Performed experiments|Approved final version of manuscript	Conception and design of research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5661918	29093646	BD	3	Conception and design of research|Performed experiments|Approved final version of manuscript	Performed experiments	Performed the experiments	Investigation	YES
5661918	29093646	BD	3	Conception and design of research|Performed experiments|Approved final version of manuscript	Approved final version of manuscript	-	-	NO
5661918	29093646	GR	3	Analysed data|Interpreted results of experiments|Approved final version of manuscript	Analysed data	Analyzed the data	Formal analysis	YES
5661918	29093646	GR	3	Analysed data|Interpreted results of experiments|Approved final version of manuscript	Interpreted results of experiments	Analyzed the data	Formal analysis	YES
5661918	29093646	GR	3	Analysed data|Interpreted results of experiments|Approved final version of manuscript	Approved final version of manuscript	-	-	NO
5661918	29093646	JT	3	Performed experiments|Approved final version of manuscript	Performed experiments	Performed the experiments	Investigation	YES
5661918	29093646	JT	3	Performed experiments|Approved final version of manuscript	Approved final version of manuscript	-	-	NO
5661918	29093646	MKR	3	Conception and design of research|Interpreted results of experiments|Drafted manuscript|Edited and revised manuscript|Approved final version of manuscript	Conception and design of research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5661918	29093646	MKR	3	Conception and design of research|Interpreted results of experiments|Drafted manuscript|Edited and revised manuscript|Approved final version of manuscript	Interpreted results of experiments	Analyzed the data	Formal analysis	YES
5661918	29093646	MKR	3	Conception and design of research|Interpreted results of experiments|Drafted manuscript|Edited and revised manuscript|Approved final version of manuscript	Drafted manuscript	Wrote the paper	Writing - Original Draft	YES
5661918	29093646	MKR	3	Conception and design of research|Interpreted results of experiments|Drafted manuscript|Edited and revised manuscript|Approved final version of manuscript	Edited and revised manuscript	Wrote the paper	Writing - Review & Editing	YES
5661918	29093646	MKR	3	Conception and design of research|Interpreted results of experiments|Drafted manuscript|Edited and revised manuscript|Approved final version of manuscript	Approved final version of manuscript	-	-	NO
5661918	29093646	NBT	3	Interpreted results of experiments|Drafted manuscript|Edited and revised manuscript|Approved final version of manuscript	Interpreted results of experiments	Analyzed the data	Formal analysis	YES
5661918	29093646	NBT	3	Interpreted results of experiments|Drafted manuscript|Edited and revised manuscript|Approved final version of manuscript	Drafted manuscript	Wrote the paper	Writing - Original Draft	YES
5661918	29093646	NBT	3	Interpreted results of experiments|Drafted manuscript|Edited and revised manuscript|Approved final version of manuscript	Edited and revised manuscript	Wrote the paper	Writing - Review & Editing	YES
5661918	29093646	NBT	3	Interpreted results of experiments|Drafted manuscript|Edited and revised manuscript|Approved final version of manuscript	Approved final version of manuscript	-	-	NO
5661918	29093646	RJ	3	Performed experiments|Approved final version of manuscript	Performed experiments	Performed the experiments	Investigation	YES
5661918	29093646	RJ	3	Performed experiments|Approved final version of manuscript	Approved final version of manuscript	-	-	NO
4416017	25928708	HT	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4416017	25928708	HT	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416017	25928708	KH	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416017	25928708	KK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4416017	25928708	KK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416017	25928708	KM	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416017	25928708	KS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4416017	25928708	KS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4416017	25928708	KS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416017	25928708	KY	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4416017	25928708	KY	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416017	25928708	M. Taniguchi	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4416017	25928708	M. Taniguchi	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4416017	25928708	M. Taniguchi	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416017	25928708	M. Tohyama	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416017	25928708	M. Tohyama	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416017	25928708	RK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416017	25928708	SK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4416017	25928708	SK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416017	25928708	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416017	25928708	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416017	25928708	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416017	25928708	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416017	25928708	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416017	25928708	TF	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4416017	25928708	TF	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416017	25928708	TH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416017	25928708	TH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416017	25928708	TH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416017	25928708	TH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416017	25928708	TK	PLoS5	Conceived and designed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416017	25928708	TK	PLoS5	Conceived and designed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4416017	25928708	TK	PLoS5	Conceived and designed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4416017	25928708	TK	PLoS5	Conceived and designed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416017	25928708	TM	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1945016	17712411	AF	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1945016	17712411	FW	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1945016	17712411	FW	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1945016	17712411	MF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1945016	17712411	MF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1945016	17712411	MF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1945016	17712411	MF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5331762	28122868	CC	2	provided reagents and aided in interpretation of results	provided reagents and aided in interpretation of results	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5331762	28122868	CL	2	designed research	designed research	Conceived and designed the experiments	Methodology	YES
5331762	28122868	DV	2	provided reagents and aided in interpretation of results	provided reagents and aided in interpretation of results	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5331762	28122868	JL	2	designed research|performed research|analyzed data and wrote the manuscript	designed research	Conceived and designed the experiments	Methodology	YES
5331762	28122868	JL	2	designed research|performed research|analyzed data and wrote the manuscript	performed research	Performed the experiments	Investigation	YES
5331762	28122868	JL	2	designed research|performed research|analyzed data and wrote the manuscript	analyzed data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5331762	28122868	MJH	2	provided reagents and aided in interpretation of results	provided reagents and aided in interpretation of results	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5331762	28122868	TAS	2	designed research|analyzed data and wrote the manuscript	designed research	Conceived and designed the experiments	Methodology	YES
5331762	28122868	TAS	2	designed research|analyzed data and wrote the manuscript	analyzed data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5331762	28122868	WX	2	performed research	performed research	Performed the experiments	Investigation	YES
5331762	28122868	YQ	2	performed research	performed research	Performed the experiments	Investigation	YES
5331762	28122868	YS	2	performed research|analyzed data and wrote the manuscript	performed research	Performed the experiments	Investigation	YES
5331762	28122868	YS	2	performed research|analyzed data and wrote the manuscript	analyzed data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4416018	25927836	AL	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416018	25927836	AL	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416018	25927836	AL	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416018	25927836	CC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416018	25927836	CC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416018	25927836	CC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416018	25927836	KL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416018	25927836	KL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416018	25927836	KL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416018	25927836	VK	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416018	25927836	VK	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416018	25927836	VK	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416018	25927836	WT	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416018	25927836	WT	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416018	25927836	WT	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5429318	28500590	All authors	2	contributed in the final approval of manuscript|read and approved the final manuscript	contributed in the final approval of manuscript	-	-	NO
5429318	28500590	All authors	2	contributed in the final approval of manuscript|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5429318	28500590	LBF-C	2	edited the manuscript|provided reagents and equipment|supervised the whole project development and analyzed results	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5429318	28500590	LBF-C	2	edited the manuscript|provided reagents and equipment|supervised the whole project development and analyzed results	provided reagents and equipment	Contributed reagents/materials/analysis tools	Resources	YES
5429318	28500590	LBF-C	2	edited the manuscript|provided reagents and equipment|supervised the whole project development and analyzed results	supervised the whole project development and analyzed results	Analyzed the data	Formal analysis|Supervision	YES
5429318	28500590	LD	2	edited the manuscript|provided reagents and equipment|supervised the whole project development and analyzed results	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5429318	28500590	LD	2	edited the manuscript|provided reagents and equipment|supervised the whole project development and analyzed results	provided reagents and equipment	Contributed reagents/materials/analysis tools	Resources	YES
5429318	28500590	LD	2	edited the manuscript|provided reagents and equipment|supervised the whole project development and analyzed results	supervised the whole project development and analyzed results	Analyzed the data	Formal analysis|Supervision	YES
5429318	28500590	MEH-L	2	supervised the whole project development and analyzed results	supervised the whole project development and analyzed results	Analyzed the data	Formal analysis|Supervision	YES
5429318	28500590	MLV-T	2	supervised the whole project development and analyzed results	supervised the whole project development and analyzed results	Analyzed the data	Formal analysis|Supervision	YES
5429318	28500590	RM	2	conceived the project, designed the experiments, interpreted results, wrote the manuscript and supervised participants|provided reagents and equipment	conceived the project, designed the experiments, interpreted results, wrote the manuscript and supervised participants	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Supervision|Writing - Original Draft	YES
5429318	28500590	RM	2	conceived the project, designed the experiments, interpreted results, wrote the manuscript and supervised participants|provided reagents and equipment	provided reagents and equipment	Contributed reagents/materials/analysis tools	Resources	YES
5429318	28500590	YB-A	2	conceived the project, designed the experiments, interpreted results, wrote the manuscript and supervised participants	conceived the project, designed the experiments, interpreted results, wrote the manuscript and supervised participants	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Supervision|Writing - Original Draft	YES
4628708	26557708	Else Kirstine Tonnesen	2	supervised the venningsen conducted the study under	supervised the venningsen conducted the study under	Performed the experiments	Investigation|Supervision	YES
4628708	26557708	Helle Svenningsen	2	conducted the study under|wrote the initial draft of the paper	conducted the study under	Performed the experiments	Investigation	YES
4628708	26557708	Helle Svenningsen	2	conducted the study under|wrote the initial draft of the paper	wrote the initial draft of the paper	Wrote the paper	Writing - Original Draft	YES
4628708	26557708	Ingrid Egerod	2	supervised the venningsen conducted the study under	supervised the venningsen conducted the study under	Performed the experiments	Investigation|Supervision	YES
4628708	26557708	Morten Frydenberg	2	led the design of the statistical analysis	led the design of the statistical analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis	YES
4628708	26557708	Poul Videbech	2	supervised the venningsen conducted the study under	supervised the venningsen conducted the study under	Performed the experiments	Investigation|Supervision	YES
4628708	26557708	all authors	2	have participated in the revision of subsequent drafts and have read and approved the final version of the paper	have participated in the revision of subsequent drafts and have read and approved the final version of the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5700566	29166857	HK	2	performed computer analyses	performed computer analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5700566	29166857	HS	2	interpreted the data and contributed significantly in drafting the manuscript	interpreted the data and contributed significantly in drafting the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5700566	29166857	HT	2	assisted in genome and rna sequence	assisted in genome and rna sequence	Performed the experiments	Investigation	YES
5700566	29166857	HY	2	performed computer analyses	performed computer analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5700566	29166857	JW	2	analyzed and interpreted the results	analyzed and interpreted the results	Analyzed the data	Formal analysis	YES
5700566	29166857	MK	2	conceived and performed experiments, computer analyses, interpreted the data, and developed the draft of the manuscript	conceived and performed experiments, computer analyses, interpreted the data, and developed the draft of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
5700566	29166857	RT	2	supervised the entire project	supervised the entire project	-	Supervision	YES
5700566	29166857	SK	2	analyzed, interpreted the results and wrote the paper	analyzed, interpreted the results and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5700566	29166857	SN	2	performed computer analyses	performed computer analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5683315	29158725	HM	2	contributed to the study conceptualization, data analysis, and manuscript writing	contributed to the study conceptualization, data analysis, and manuscript writing	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Resources|Writing - Original Draft	YES
5683315	29158725	PAK	2	contributed to the study conceptualization, data collection, and manuscript revision	contributed to the study conceptualization, data collection, and manuscript revision	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Investigation|Resources|Writing - Review & Editing	YES
5683315	29158725	RZ	2	contributed to the study conceptualization, data collection, and manuscript revision	contributed to the study conceptualization, data collection, and manuscript revision	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Investigation|Resources|Writing - Review & Editing	YES
5683315	29158725	TM	2	contributed to manuscript revision	contributed to manuscript revision	Wrote the paper	Writing - Review & Editing	YES
5776123	29387075	AM	7	collected the data|edited the manuscript during all phases	collected the data	Performed the experiments	Investigation	YES
5776123	29387075	AM	7	collected the data|edited the manuscript during all phases	edited the manuscript during all phases	Wrote the paper	Writing - Review & Editing	YES
5776123	29387075	HS-S	7	edited the manuscript during all phases	edited the manuscript during all phases	Wrote the paper	Writing - Review & Editing	YES
5776123	29387075	JC	7	obtained funding to support the project|collected the data|edited the manuscript during all phases	obtained funding to support the project	-	Funding acquisition	YES
5776123	29387075	JC	7	obtained funding to support the project|collected the data|edited the manuscript during all phases	collected the data	Performed the experiments	Investigation	YES
5776123	29387075	JC	7	obtained funding to support the project|collected the data|edited the manuscript during all phases	edited the manuscript during all phases	Wrote the paper	Writing - Review & Editing	YES
5776123	29387075	JvL	7	analyzed the data|edited the manuscript during all phases	analyzed the data	Analyzed the data	Formal analysis	YES
5776123	29387075	JvL	7	analyzed the data|edited the manuscript during all phases	edited the manuscript during all phases	Wrote the paper	Writing - Review & Editing	YES
5776123	29387075	MS	7	edited the manuscript during all phases	edited the manuscript during all phases	Wrote the paper	Writing - Review & Editing	YES
5776123	29387075	NK	7	edited the manuscript during all phases	edited the manuscript during all phases	Wrote the paper	Writing - Review & Editing	YES
5776123	29387075	PK	7	obtained funding to support the project|collected the data|analyzed the data|conceived ideas and led the manuscript writing	obtained funding to support the project	-	Funding acquisition	YES
5776123	29387075	PK	7	obtained funding to support the project|collected the data|analyzed the data|conceived ideas and led the manuscript writing	collected the data	Performed the experiments	Investigation	YES
5776123	29387075	PK	7	obtained funding to support the project|collected the data|analyzed the data|conceived ideas and led the manuscript writing	analyzed the data	Analyzed the data	Formal analysis	YES
5776123	29387075	PK	7	obtained funding to support the project|collected the data|analyzed the data|conceived ideas and led the manuscript writing	conceived ideas and led the manuscript writing	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5776123	29387075	RC	7	collected the data|analyzed the data|edited the manuscript during all phases	collected the data	Performed the experiments	Investigation	YES
5776123	29387075	RC	7	collected the data|analyzed the data|edited the manuscript during all phases	analyzed the data	Analyzed the data	Formal analysis	YES
5776123	29387075	RC	7	collected the data|analyzed the data|edited the manuscript during all phases	edited the manuscript during all phases	Wrote the paper	Writing - Review & Editing	YES
5776123	29387075	VC	7	analyzed the data|conceived ideas and led the manuscript writing|edited the manuscript during all phases	analyzed the data	Analyzed the data	Formal analysis	YES
5776123	29387075	VC	7	analyzed the data|conceived ideas and led the manuscript writing|edited the manuscript during all phases	conceived ideas and led the manuscript writing	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5776123	29387075	VC	7	analyzed the data|conceived ideas and led the manuscript writing|edited the manuscript during all phases	edited the manuscript during all phases	Wrote the paper	Writing - Review & Editing	YES
5776123	29387075	WvdK	7	edited the manuscript during all phases	edited the manuscript during all phases	Wrote the paper	Writing - Review & Editing	YES
1945082	17712424	AG	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1945082	17712424	AG	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1945082	17712424	KS	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1945082	17712424	KS	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1945082	17712424	MT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1945082	17712424	MT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1945082	17712424	MT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1945082	17712424	MT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1945082	17712424	MT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1945082	17712424	MT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1945082	17712424	MT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1945082	17712424	SA	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1945082	17712424	SA	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1945082	17712424	SA	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1945082	17712424	SW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1945082	17712424	SW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1945082	17712424	SW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1945082	17712424	VP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1945082	17712424	VP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1945082	17712424	VP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1945082	17712424	ZY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1945082	17712424	ZY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1945082	17712424	ZY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1945082	17712424	ZY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1945082	17712424	ZY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416019	25928306	AA	PLoS5	Conceived and designed the experiments|Wrote the paper|Interpreted the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416019	25928306	AA	PLoS5	Conceived and designed the experiments|Wrote the paper|Interpreted the data	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416019	25928306	AA	PLoS5	Conceived and designed the experiments|Wrote the paper|Interpreted the data	Interpreted the data	Analyzed the data	Formal analysis	YES
4416019	25928306	CCC	PLoS5	Wrote the paper|Interpreted the data	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416019	25928306	CCC	PLoS5	Wrote the paper|Interpreted the data	Interpreted the data	Analyzed the data	Formal analysis	YES
4416019	25928306	EWG	PLoS5	Conceived and designed the experiments|Wrote the paper|Interpreted the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416019	25928306	EWG	PLoS5	Conceived and designed the experiments|Wrote the paper|Interpreted the data	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416019	25928306	EWG	PLoS5	Conceived and designed the experiments|Wrote the paper|Interpreted the data	Interpreted the data	Analyzed the data	Formal analysis	YES
4416019	25928306	GI	PLoS5	Conceived and designed the experiments|Wrote the paper|Interpreted the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416019	25928306	GI	PLoS5	Conceived and designed the experiments|Wrote the paper|Interpreted the data	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416019	25928306	GI	PLoS5	Conceived and designed the experiments|Wrote the paper|Interpreted the data	Interpreted the data	Analyzed the data	Formal analysis	YES
4416019	25928306	JBA	PLoS5	Wrote the paper|Interpreted the data	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416019	25928306	JBA	PLoS5	Wrote the paper|Interpreted the data	Interpreted the data	Analyzed the data	Formal analysis	YES
4416019	25928306	KMB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Interpreted the data|Wrote the first draft	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416019	25928306	KMB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Interpreted the data|Wrote the first draft	Analyzed the data	Analyzed the data	Formal analysis	YES
4416019	25928306	KMB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Interpreted the data|Wrote the first draft	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416019	25928306	KMB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Interpreted the data|Wrote the first draft	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416019	25928306	KMB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Interpreted the data|Wrote the first draft	Interpreted the data	Analyzed the data	Formal analysis	YES
4416019	25928306	KMB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Interpreted the data|Wrote the first draft	Wrote the first draft	Wrote the paper	Writing - Original Draft	YES
4416019	25928306	LSG	PLoS5	Conceived and designed the experiments|Wrote the paper|Interpreted the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416019	25928306	LSG	PLoS5	Conceived and designed the experiments|Wrote the paper|Interpreted the data	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416019	25928306	LSG	PLoS5	Conceived and designed the experiments|Wrote the paper|Interpreted the data	Interpreted the data	Analyzed the data	Formal analysis	YES
4416019	25928306	MKA	PLoS5	Conceived and designed the experiments|Wrote the paper|Interpreted the data|Wrote the first draft	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416019	25928306	MKA	PLoS5	Conceived and designed the experiments|Wrote the paper|Interpreted the data|Wrote the first draft	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416019	25928306	MKA	PLoS5	Conceived and designed the experiments|Wrote the paper|Interpreted the data|Wrote the first draft	Interpreted the data	Analyzed the data	Formal analysis	YES
4416019	25928306	MKA	PLoS5	Conceived and designed the experiments|Wrote the paper|Interpreted the data|Wrote the first draft	Wrote the first draft	Wrote the paper	Writing - Original Draft	YES
4416019	25928306	NS	PLoS5	Wrote the paper|Interpreted the data	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416019	25928306	NS	PLoS5	Wrote the paper|Interpreted the data	Interpreted the data	Analyzed the data	Formal analysis	YES
4416019	25928306	SHS	PLoS5	Conceived and designed the experiments|Wrote the paper|Interpreted the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416019	25928306	SHS	PLoS5	Conceived and designed the experiments|Wrote the paper|Interpreted the data	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416019	25928306	SHS	PLoS5	Conceived and designed the experiments|Wrote the paper|Interpreted the data	Interpreted the data	Analyzed the data	Formal analysis	YES
5683453	29158726	RAD	2	secured funding and oversaw the whole project	secured funding and oversaw the whole project	-	Funding acquisition|Supervision	YES
5683453	29158726	SH	2	helped design logistics and other aspects of the research, and took a major role in collecting data	helped design logistics and other aspects of the research, and took a major role in collecting data	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Project administration	YES
5350561	28242756	All authors	2	commented on the manuscript	commented on the manuscript	-	-	NO
5350561	28242756	CT	2	performed and interpreted most experiments, and were involved in designing some experiments	performed and interpreted most experiments, and were involved in designing some experiments	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5350561	28242756	DDD	2	helped preparing primary cultures and took care of the animal colonies	helped preparing primary cultures and took care of the animal colonies	Performed the experiments	Investigation	YES
5350561	28242756	GB	2	performed and interpreted most experiments, and were involved in designing some experiments	performed and interpreted most experiments, and were involved in designing some experiments	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5350561	28242756	MB	2	performed and interpreted most experiments, and were involved in designing some experiments	performed and interpreted most experiments, and were involved in designing some experiments	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5350561	28242756	MP	2	conceived and supervised the project, designed experiments, interpreted data, and wrote the manuscript	conceived and supervised the project, designed experiments, interpreted data, and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Supervision|Writing - Original Draft	YES
5350561	28242756	SF	2	produced all viral preparations	produced all viral preparations	-	-	NO
5350561	28242756	VK	2	carried out experiments and performed kinase assays	carried out experiments and performed kinase assays	Performed the experiments	Investigation	YES
5700656	29166853	CYC	2	carried out the itraq data analysis	carried out the itraq data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5700656	29166853	JFC	2	conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5700656	29166853	JL	2	conceived the study|performed most of the experiments|interpreted the results and wrote the paper	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5700656	29166853	JL	2	conceived the study|performed most of the experiments|interpreted the results and wrote the paper	performed most of the experiments	Performed the experiments	Investigation	YES
5700656	29166853	JL	2	conceived the study|performed most of the experiments|interpreted the results and wrote the paper	interpreted the results and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5700656	29166853	JX	2	performed most of the experiments|performed the phytohormone measurement	performed most of the experiments	Performed the experiments	Investigation	YES
5700656	29166853	JX	2	performed most of the experiments|performed the phytohormone measurement	performed the phytohormone measurement	Performed the experiments	Investigation	YES
5700656	29166853	KJZ	2	carried out the itraq data analysis	carried out the itraq data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5700656	29166853	QFL	2	gave useful advices and contributed to experiments	gave useful advices and contributed to experiments	Performed the experiments	Investigation	YES
5700656	29166853	QWG	2	helped to prepare samples for itraq	helped to prepare samples for itraq	Performed the experiments	Investigation	YES
5700656	29166853	TZ	2	carried out the itraq data analysis	carried out the itraq data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5700656	29166853	ZW	2	carried out the itraq data analysis	carried out the itraq data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5432455	28508385	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5432455	28508385	DH	2	performed the purification of recombinant xylanases and the analysis of enzymatic properties	performed the purification of recombinant xylanases and the analysis of enzymatic properties	Performed the experiments	Investigation	YES
5432455	28508385	JL	2	directed the overall study and revised the manuscript	directed the overall study and revised the manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
5432455	28508385	MW	2	directed the overall study and revised the manuscript	directed the overall study and revised the manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
5432455	28508385	QW	2	carried out the prediction of aoxyn11as variants, the site-saturation and site-directed mutagenesis of aoxyn11a and the expression of its variant genes, and drafted the manuscript	carried out the prediction of aoxyn11as variants, the site-saturation and site-directed mutagenesis of aoxyn11a and the expression of its variant genes, and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Supervision|Writing - Original Draft	YES
5432455	28508385	RW	2	performed the purification of recombinant xylanases and the analysis of enzymatic properties	performed the purification of recombinant xylanases and the analysis of enzymatic properties	Performed the experiments	Investigation	YES
5432455	28508385	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5432455	28508385	XL	2	carried out the prediction of aoxyn11as variants, the site-saturation and site-directed mutagenesis of aoxyn11a and the expression of its variant genes, and drafted the manuscript	carried out the prediction of aoxyn11as variants, the site-saturation and site-directed mutagenesis of aoxyn11a and the expression of its variant genes, and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Supervision|Writing - Original Draft	YES
5432455	28508385	YL	2	performed the purification of recombinant xylanases and the analysis of enzymatic properties	performed the purification of recombinant xylanases and the analysis of enzymatic properties	Performed the experiments	Investigation	YES
4387516	25823872	A.M.	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4387516	25823872	All authors	2	gave final approval for publication	gave final approval for publication	-	-	NO
4387516	25823872	H.O.	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4387516	25823872	K.K.	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4416020	25928424	DL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416020	25928424	ES	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416020	25928424	JW	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416020	25928424	JZ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416020	25928424	QM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416020	25928424	QM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416020	25928424	QM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416020	25928424	QM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416020	25928424	WS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416020	25928424	XZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416020	25928424	XZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416020	25928424	XZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416020	25928424	XZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416020	25928424	YQ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416020	25928424	YQ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416020	25928424	YQ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416020	25928424	YQ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416020	25928424	ZZ	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4416020	25928424	ZZ	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5776130	29387077	All authors	2	give final approval for publication	give final approval for publication	-	-	NO
5776130	29387077	DZ	2	contributed to the preparation of experiment materials	contributed to the preparation of experiment materials	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5776130	29387077	FL	2	contributed to the preparation of experiment materials	contributed to the preparation of experiment materials	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5776130	29387077	FY	2	contributed to the preparation of experiment materials	contributed to the preparation of experiment materials	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5776130	29387077	XGZ	2	designed the experiments|performed data analysis and wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5776130	29387077	XGZ	2	designed the experiments|performed data analysis and wrote the manuscript	performed data analysis and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5776130	29387077	XS	2	contributed equally to this work|designed the experiments|carried out all experimental work|performed data analysis and wrote the manuscript	contributed equally to this work	-	-	NO
5776130	29387077	XS	2	contributed equally to this work|designed the experiments|carried out all experimental work|performed data analysis and wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5776130	29387077	XS	2	contributed equally to this work|designed the experiments|carried out all experimental work|performed data analysis and wrote the manuscript	carried out all experimental work	Performed the experiments	Investigation	YES
5776130	29387077	XS	2	contributed equally to this work|designed the experiments|carried out all experimental work|performed data analysis and wrote the manuscript	performed data analysis and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5776130	29387077	XT	2	contributed equally to this work|carried out all experimental work|performed data analysis and wrote the manuscript	contributed equally to this work	-	-	NO
5776130	29387077	XT	2	contributed equally to this work|carried out all experimental work|performed data analysis and wrote the manuscript	carried out all experimental work	Performed the experiments	Investigation	YES
5776130	29387077	XT	2	contributed equally to this work|carried out all experimental work|performed data analysis and wrote the manuscript	performed data analysis and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5776130	29387077	XZ	2	contributed to the preparation of experiment materials	contributed to the preparation of experiment materials	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5776130	29387077	YL	2	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5776130	29387077	YZ	2	contributed to the preparation of experiment materials	contributed to the preparation of experiment materials	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5697135	29200983	AZ	PLoS52	conceived and designed the study|were involved with data collection|wrote the paper	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5697135	29200983	AZ	PLoS52	conceived and designed the study|were involved with data collection|wrote the paper	were involved with data collection	Performed the experiments	Investigation	YES
5697135	29200983	AZ	PLoS52	conceived and designed the study|were involved with data collection|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5697135	29200983	All authors	PLoS52	were involved in the study|reviewed the paper and approved the final version prior to submission	were involved in the study	-	-	NO
5697135	29200983	All authors	PLoS52	were involved in the study|reviewed the paper and approved the final version prior to submission	reviewed the paper and approved the final version prior to submission	Wrote the paper	Writing - Review & Editing	YES
5697135	29200983	CS	PLoS52	were involved with data collection	were involved with data collection	Performed the experiments	Investigation	YES
5697135	29200983	JJ	PLoS52	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5697135	29200983	JR	PLoS52	conceived and designed the study|were involved with data collection|wrote the paper	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5697135	29200983	JR	PLoS52	conceived and designed the study|were involved with data collection|wrote the paper	were involved with data collection	Performed the experiments	Investigation	YES
5697135	29200983	JR	PLoS52	conceived and designed the study|were involved with data collection|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
1945083	17726518	CB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1945083	17726518	CB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1945083	17726518	CB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1945083	17726518	HB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1945083	17726518	JW	PLoS5	Performed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1945083	17726518	JW	PLoS5	Performed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1945083	17726518	JW	PLoS5	Performed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1945083	17726518	JW	PLoS5	Performed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1945083	17726518	LO	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1945083	17726518	NG	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1945083	17726518	NG	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1945083	17726518	RN	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1945083	17726518	RN	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1945083	17726518	RN	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1945083	17726518	TM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1945083	17726518	TM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1945083	17726518	TM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1945083	17726518	TM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3872401	24385881	Chu-Wen Li	2	contributed equally to this work	contributed equally to this work	-	-	NO
3872401	24385881	Xiao-Li Wu	2	contributed equally to this work	contributed equally to this work	-	-	NO
4416021	25928713	AC	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416021	25928713	AM	PLoS5	Wrote the paper|Literature review	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416021	25928713	AM	PLoS5	Wrote the paper|Literature review	Literature review	-	Formal analysis	YES
4416021	25928713	AS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416021	25928713	AS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416021	25928713	AS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416021	25928713	CH	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416021	25928713	CH	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416021	25928713	HB	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416021	25928713	RM	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416021	25928713	RM	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5432459	28508386	MI	1	Drafting and literature survey	Drafting and literature survey	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5432459	28508386	TA	1	Experimentation	Experimentation	Performed the experiments	Investigation	YES
5432459	28508386	YW	1	Planning and designing of study	Planning and designing of study	Conceived and designed the experiments	Methodology	YES
5391139	28275011	AH	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5391139	28275011	AH	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5391139	28275011	AP	PLoS52	designed the research|performed the experiments|analyzed the data|wrote the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
5391139	28275011	AP	PLoS52	designed the research|performed the experiments|analyzed the data|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5391139	28275011	AP	PLoS52	designed the research|performed the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5391139	28275011	AP	PLoS52	designed the research|performed the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5391139	28275011	CB	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5391139	28275011	FAS	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5391139	28275011	HvA	PLoS52	designed the research|analyzed the data|wrote the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
5391139	28275011	HvA	PLoS52	designed the research|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5391139	28275011	HvA	PLoS52	designed the research|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5391139	28275011	KA	PLoS52	designed the research|performed the experiments|analyzed the data	designed the research	Conceived and designed the experiments	Methodology	YES
5391139	28275011	KA	PLoS52	designed the research|performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5391139	28275011	KA	PLoS52	designed the research|performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5391139	28275011	LKH	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5391139	28275011	MM	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5391139	28275011	MSL	PLoS52	designed the research|performed the experiments|analyzed the data|wrote the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
5391139	28275011	MSL	PLoS52	designed the research|performed the experiments|analyzed the data|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5391139	28275011	MSL	PLoS52	designed the research|performed the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5391139	28275011	MSL	PLoS52	designed the research|performed the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5391139	28275011	NPD	PLoS52	designed the research|analyzed the data|wrote the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
5391139	28275011	NPD	PLoS52	designed the research|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5391139	28275011	NPD	PLoS52	designed the research|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5391139	28275011	WWW	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5700742	29166879	All authors	2	have assisted in the writing of the manuscript and have read and approved the final submitted version of the manuscript	have assisted in the writing of the manuscript and have read and approved the final submitted version of the manuscript	Wrote the paper	Writing - Original Draft	YES
5700742	29166879	MPT	2	conceived of the project and was responsible for directing all of the research activities	conceived of the project and was responsible for directing all of the research activities	Conceived and designed the experiments	Conceptualization	YES
5700742	29166879	VAM	2	carried out the computational analysis of the tfs with the	carried out the computational analysis of the tfs with the	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5700742	29166879	YW	2	assisted with the carried out the computational analysis of the tfs with the	assisted with the carried out the computational analysis of the tfs with the	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
1945084	17712425	JJ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1945084	17712425	JJ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1945084	17712425	MP	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1945084	17712425	MP	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1945084	17712425	SD	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1945084	17712425	SD	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1945084	17712425	TR	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1945084	17712425	TR	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4410375	25870395	B.H.	PLoS52	collected and analysed the data|wrote the paper	collected and analysed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4410375	25870395	B.H.	PLoS52	collected and analysed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4410375	25870395	E.A.A.	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5433943	28510221	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5697397	29200982	ALN	2	conducted research|analysed data	conducted research	Performed the experiments	Investigation	YES
5697397	29200982	ALN	2	conducted research|analysed data	analysed data	Analyzed the data	Formal analysis	YES
5697397	29200982	EB	2	designed research|wrote paper	designed research	Conceived and designed the experiments	Methodology	YES
5697397	29200982	EB	2	designed research|wrote paper	wrote paper	Wrote the paper	Writing - Original Draft	YES
5697397	29200982	GP	2	designed research|wrote paper	designed research	Conceived and designed the experiments	Methodology	YES
5697397	29200982	GP	2	designed research|wrote paper	wrote paper	Wrote the paper	Writing - Original Draft	YES
5697397	29200982	HB	2	designed research|wrote paper	designed research	Conceived and designed the experiments	Methodology	YES
5697397	29200982	HB	2	designed research|wrote paper	wrote paper	Wrote the paper	Writing - Original Draft	YES
5697397	29200982	HH	2	designed research|conducted research|analysed data|wrote paper|had primary responsibility for final content	designed research	Conceived and designed the experiments	Methodology	YES
5697397	29200982	HH	2	designed research|conducted research|analysed data|wrote paper|had primary responsibility for final content	conducted research	Performed the experiments	Investigation	YES
5697397	29200982	HH	2	designed research|conducted research|analysed data|wrote paper|had primary responsibility for final content	analysed data	Analyzed the data	Formal analysis	YES
5697397	29200982	HH	2	designed research|conducted research|analysed data|wrote paper|had primary responsibility for final content	wrote paper	Wrote the paper	Writing - Original Draft	YES
5697397	29200982	HH	2	designed research|conducted research|analysed data|wrote paper|had primary responsibility for final content	had primary responsibility for final content	-	-	NO
5697397	29200982	IG	2	designed research|wrote paper	designed research	Conceived and designed the experiments	Methodology	YES
5697397	29200982	IG	2	designed research|wrote paper	wrote paper	Wrote the paper	Writing - Original Draft	YES
5697397	29200982	KH	2	conducted research|analysed data	conducted research	Performed the experiments	Investigation	YES
5697397	29200982	KH	2	conducted research|analysed data	analysed data	Analyzed the data	Formal analysis	YES
5697397	29200982	MC	2	analysed data|wrote paper	analysed data	Analyzed the data	Formal analysis	YES
5697397	29200982	MC	2	analysed data|wrote paper	wrote paper	Wrote the paper	Writing - Original Draft	YES
5697397	29200982	SNA	2	conducted research|analysed data|wrote paper	conducted research	Performed the experiments	Investigation	YES
5697397	29200982	SNA	2	conducted research|analysed data|wrote paper	analysed data	Analyzed the data	Formal analysis	YES
5697397	29200982	SNA	2	conducted research|analysed data|wrote paper	wrote paper	Wrote the paper	Writing - Original Draft	YES
5697397	29200982	TR	2	designed research|wrote paper	designed research	Conceived and designed the experiments	Methodology	YES
5697397	29200982	TR	2	designed research|wrote paper	wrote paper	Wrote the paper	Writing - Original Draft	YES
5391140	28336682	AS	2	conceived the project|designed experiments|performed experiments|wrote the paper, and all authors edited the manuscript	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5391140	28336682	AS	2	conceived the project|designed experiments|performed experiments|wrote the paper, and all authors edited the manuscript	designed experiments	Conceived and designed the experiments	Methodology	YES
5391140	28336682	AS	2	conceived the project|designed experiments|performed experiments|wrote the paper, and all authors edited the manuscript	performed experiments	Performed the experiments	Investigation	YES
5391140	28336682	AS	2	conceived the project|designed experiments|performed experiments|wrote the paper, and all authors edited the manuscript	wrote the paper, and all authors edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5391140	28336682	CW	2	designed experiments|performed experiments	designed experiments	Conceived and designed the experiments	Methodology	YES
5391140	28336682	CW	2	designed experiments|performed experiments	performed experiments	Performed the experiments	Investigation	YES
5391140	28336682	JV	2	conceived the project|wrote the paper, and all authors edited the manuscript	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5391140	28336682	JV	2	conceived the project|wrote the paper, and all authors edited the manuscript	wrote the paper, and all authors edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5391140	28336682	LLD	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
4416022	25928810	AM	PLoS5	Performed the experiments|Assay design and development	Performed the experiments	Performed the experiments	Investigation	YES
4416022	25928810	AM	PLoS5	Performed the experiments|Assay design and development	Assay design and development	Conceived and designed the experiments|Performed the experiments	Investigation	YES
4416022	25928810	DHM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416022	25928810	GPY	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416022	25928810	GPY	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416022	25928810	LCL	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416022	25928810	LCL	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416022	25928810	MT	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416022	25928810	PLM	PLoS5	Data analysis contribution	Data analysis contribution	Analyzed the data	Formal analysis	YES
4416022	25928810	RTB	PLoS5	Performed the experiments|Assay design and development	Performed the experiments	Performed the experiments	Investigation	YES
4416022	25928810	RTB	PLoS5	Performed the experiments|Assay design and development	Assay design and development	Conceived and designed the experiments|Performed the experiments	Investigation	YES
4416022	25928810	SKP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416022	25928810	SKP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416022	25928810	SKP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416022	25928810	SM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416022	25928810	TL	PLoS5	Data analysis contribution	Data analysis contribution	Analyzed the data	Formal analysis	YES
5776131	29387074	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
1945085	17712426	AL	PLoS5	Analyzed the data|Wrote the paper|Approved final version of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
1945085	17712426	AL	PLoS5	Analyzed the data|Wrote the paper|Approved final version of the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1945085	17712426	AL	PLoS5	Analyzed the data|Wrote the paper|Approved final version of the manuscript	Approved final version of the manuscript	-	-	NO
1945085	17712426	CC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Approved final version of the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1945085	17712426	CC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Approved final version of the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
1945085	17712426	CC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Approved final version of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
1945085	17712426	CC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Approved final version of the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1945085	17712426	CC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Approved final version of the manuscript	Approved final version of the manuscript	-	-	NO
1945085	17712426	FJ	PLoS5	Contributed reagents/materials/analysis tools|Approved final version of the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1945085	17712426	FJ	PLoS5	Contributed reagents/materials/analysis tools|Approved final version of the manuscript	Approved final version of the manuscript	-	-	NO
1945085	17712426	JC	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1945085	17712426	JC	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1945085	17712426	JK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Approved final version of the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1945085	17712426	JK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Approved final version of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
1945085	17712426	JK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Approved final version of the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1945085	17712426	JK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Approved final version of the manuscript	Approved final version of the manuscript	-	-	NO
1945085	17712426	KK	PLoS5	Analyzed the data|Wrote the paper|Approved final version of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
1945085	17712426	KK	PLoS5	Analyzed the data|Wrote the paper|Approved final version of the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1945085	17712426	KK	PLoS5	Analyzed the data|Wrote the paper|Approved final version of the manuscript	Approved final version of the manuscript	-	-	NO
1945085	17712426	SK	PLoS5	Conceived and designed the experiments|Analyzed the data|Approved final version of the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1945085	17712426	SK	PLoS5	Conceived and designed the experiments|Analyzed the data|Approved final version of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
1945085	17712426	SK	PLoS5	Conceived and designed the experiments|Analyzed the data|Approved final version of the manuscript	Approved final version of the manuscript	-	-	NO
1945085	17712426	SL	PLoS5	Performed the experiments|Approved final version of the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
1945085	17712426	SL	PLoS5	Performed the experiments|Approved final version of the manuscript	Approved final version of the manuscript	-	-	NO
1945085	17712426	TC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Approved final version of the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1945085	17712426	TC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Approved final version of the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
1945085	17712426	TC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Approved final version of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
1945085	17712426	TC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Approved final version of the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1945085	17712426	TC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Approved final version of the manuscript	Approved final version of the manuscript	-	-	NO
4628713	26557702	Hye Jin Chung	2	are co-first authors and equally contributed to this work	are co-first authors and equally contributed to this work	-	-	NO
4628713	26557702	Hyung Bin Hwang	2	are co-first authors and equally contributed to this work	are co-first authors and equally contributed to this work	-	-	NO
5700745	29166855	DG	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5700745	29166855	FD	2	analyzed the sequence data and drafted the manuscript	analyzed the sequence data and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5700745	29166855	JMF	2	participated in rna extraction, carried out the quantitative real time pcr and gene clone	participated in rna extraction, carried out the quantitative real time pcr and gene clone	Performed the experiments	Investigation	YES
5700745	29166855	TW	2	participated in rna extraction, carried out the quantitative real time pcr and gene clone	participated in rna extraction, carried out the quantitative real time pcr and gene clone	Performed the experiments	Investigation	YES
5700745	29166855	YPX	2	conceived and designed the experiment|revised the manuscript	conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5700745	29166855	YPX	2	conceived and designed the experiment|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5700745	29166855	YW	2	participated in data analysis and manuscript drafting	participated in data analysis and manuscript drafting	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5700745	29166855	ZSG	2	conceived and designed the experiment|revised the manuscript	conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5700745	29166855	ZSG	2	conceived and designed the experiment|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5438323	28532122	AK	2	participated in conception of the study|co-coordinated this research project	participated in conception of the study	Conceived and designed the experiments	Conceptualization	YES
5438323	28532122	AK	2	participated in conception of the study|co-coordinated this research project	co-coordinated this research project	-	Project administration	YES
5438323	28532122	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5438323	28532122	BP	2	co-coordinated this research project	co-coordinated this research project	-	Project administration	YES
5438323	28532122	CO	2	designed experiments for the cloning and characterization of a b-mannanase|analyzed and interpreted the data|participated in conception of the study|co-coordinated this research project	designed experiments for the cloning and characterization of a b-mannanase	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5438323	28532122	CO	2	designed experiments for the cloning and characterization of a b-mannanase|analyzed and interpreted the data|participated in conception of the study|co-coordinated this research project	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5438323	28532122	CO	2	designed experiments for the cloning and characterization of a b-mannanase|analyzed and interpreted the data|participated in conception of the study|co-coordinated this research project	participated in conception of the study	Conceived and designed the experiments	Conceptualization	YES
5438323	28532122	CO	2	designed experiments for the cloning and characterization of a b-mannanase|analyzed and interpreted the data|participated in conception of the study|co-coordinated this research project	co-coordinated this research project	-	Project administration	YES
5438323	28532122	HM	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5438323	28532122	JL	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5438323	28532122	NK	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5438323	28532122	NR	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5438323	28532122	PL	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5438323	28532122	SNN	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5700683	29200984	AY	7	design of the study, manuscript preparation	design of the study, manuscript preparation	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5700683	29200984	KK	7	conception and design of the study, acquisition of data, data analysis, manuscript preparation	conception and design of the study, acquisition of data, data analysis, manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5700683	29200984	KS	7	design and coordination of the study, manuscript preparation	design and coordination of the study, manuscript preparation	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft	YES
5700683	29200984	MF	7	design of the study, data analysis, manuscript preparation	design of the study, data analysis, manuscript preparation	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5700683	29200984	TH	7	design of the study, manuscript preparation	design of the study, manuscript preparation	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5700683	29200984	TK	7	conception and design of the study, manuscript preparation|design of the study, manuscript preparation	conception and design of the study, manuscript preparation	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
5700683	29200984	TK	7	conception and design of the study, manuscript preparation|design of the study, manuscript preparation	design of the study, manuscript preparation	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4416023	25927440	AR	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4416023	25927440	AR	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416023	25927440	DvG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416023	25927440	DvG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416023	25927440	DvG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416023	25927440	GvL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4416023	25927440	GvL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416023	25927440	IB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416023	25927440	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416023	25927440	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416023	25927440	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416023	25927440	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416023	25927440	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416023	25927440	JH	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416023	25927440	JH	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416023	25927440	JP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416023	25927440	JP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416023	25927440	KN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416023	25927440	KN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416023	25927440	KN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416023	25927440	KN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416023	25927440	NJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416023	25927440	NJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416023	25927440	NJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416023	25927440	NV	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416023	25927440	RK	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416023	25927440	RK	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416023	25927440	SB	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4416023	25927440	SB	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5412822	28258062	CK-M	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5412822	28258062	DDM	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5412822	28258062	EL	2	designed the research and wrote the manuscript|performed experiments	designed the research and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5412822	28258062	EL	2	designed the research and wrote the manuscript|performed experiments	performed experiments	Performed the experiments	Investigation	YES
5412822	28258062	HW	2	conceived the project|designed the research and wrote the manuscript	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5412822	28258062	HW	2	conceived the project|designed the research and wrote the manuscript	designed the research and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5412822	28258062	LT	2	helped establish knockout cell lines	helped establish knockout cell lines	Performed the experiments	Investigation	YES
5412822	28258062	MR	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5412822	28258062	MRS	2	provided active caspase-3, caspase-8 and caspase-10a	provided active caspase-3, caspase-8 and caspase-10a	-	-	NO
5412822	28258062	MS	2	helped establish knockout cell lines	helped establish knockout cell lines	Performed the experiments	Investigation	YES
5412822	28258062	PD	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5412822	28258062	SK	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5412822	28258062	TH	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5412822	28258062	YS	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
1945086	17726522	AL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1945086	17726522	CS	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1945086	17726522	CS	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1945086	17726522	KP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1945086	17726522	KP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1945086	17726522	KP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1945086	17726522	KP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5776132	29387076	HB	PLoS52	constructed wild rice introgression lines to isolate dj15, and performed saline field tests	constructed wild rice introgression lines to isolate dj15, and performed saline field tests	Performed the experiments	Investigation	YES
5776132	29387076	HZ	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5776132	29387076	JH	PLoS52	constructed wild rice introgression lines to isolate dj15, and performed saline field tests	constructed wild rice introgression lines to isolate dj15, and performed saline field tests	Performed the experiments	Investigation	YES
5776132	29387076	RH	PLoS52	conceived the project	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5776132	29387076	RQ	PLoS52	performed the rest of experiments and analyzed data|wrote the manuscript	performed the rest of experiments and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5776132	29387076	RQ	PLoS52	performed the rest of experiments and analyzed data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5776132	29387076	SL	PLoS52	constructed wild rice introgression lines to isolate dj15, and performed saline field tests	constructed wild rice introgression lines to isolate dj15, and performed saline field tests	Performed the experiments	Investigation	YES
5776132	29387076	XL	PLoS52	constructed wild rice introgression lines to isolate dj15, and performed saline field tests	constructed wild rice introgression lines to isolate dj15, and performed saline field tests	Performed the experiments	Investigation	YES
5776132	29387076	YZ	PLoS52	constructed wild rice introgression lines to isolate dj15, and performed saline field tests	constructed wild rice introgression lines to isolate dj15, and performed saline field tests	Performed the experiments	Investigation	YES
5776132	29387076	ZZ	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
4628714	26557701	Bradley McPherson	2	developed the initial idea for the study|designed the study	developed the initial idea for the study	Conceived and designed the experiments	Conceptualization	YES
4628714	26557701	Bradley McPherson	2	developed the initial idea for the study|designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
4628714	26557701	Zoe Yee Ting	2	designed the study|performed the data collection and drafted the initial paper	designed the study	Conceived and designed the experiments	Methodology	YES
4628714	26557701	Zoe Yee Ting	2	designed the study|performed the data collection and drafted the initial paper	performed the data collection and drafted the initial paper	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4416024	25927233	LL	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416024	25927233	TRC	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416024	25927233	XJG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416024	25927233	XJG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416024	25927233	XJG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416024	25927233	XJG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416024	25927233	XJG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5701360	29169319	BSG	2	performed part of the experiments and participated in the analysis and writing of the manuscript	performed part of the experiments and participated in the analysis and writing of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5701360	29169319	IBG	2	performed part of the experiments	performed part of the experiments	Performed the experiments	Investigation	YES
5701360	29169319	JK	2	analyzed part of the data	analyzed part of the data	Analyzed the data	Formal analysis	YES
5701360	29169319	MRM	2	participated in the analysis and writing of the manuscript	participated in the analysis and writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5701360	29169319	MZ	2	performed the bioinformatics analysis	performed the bioinformatics analysis	Performed the experiments	Formal analysis|Investigation	YES
5701360	29169319	RPdV	2	designed the study and participated in the analysis and writing of the manuscript	designed the study and participated in the analysis and writing of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5704438	29209154	AGC	2	participated in data collection and data processing	participated in data collection and data processing	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5704438	29209154	AKH	2	participated in data collection and data processing	participated in data collection and data processing	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5704438	29209154	AYM	2	participated in data collection and data processing	participated in data collection and data processing	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5704438	29209154	GMT	2	designed the study, performed statistical analyses, and wrote the manuscript	designed the study, performed statistical analyses, and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5704438	29209154	JGP	2	participated in data collection and data processing	participated in data collection and data processing	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5704438	29209154	MAH	2	aided in study design and supervised data collection	aided in study design and supervised data collection	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Supervision	YES
5704438	29209154	TBP	2	created custom software, aided in data processing and interpretation, and provided input on study design	created custom software, aided in data processing and interpretation, and provided input on study design	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Formal analysis|Methodology|Software	YES
5704438	29209154	VAU	2	participated in data collection and data processing	participated in data collection and data processing	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
4424438	25918446	A.K.	3	Formulated original question|Developed modelling approach|Programmed model|Interpreted results|Wrote first draft|And revised manuscript	Formulated original question	Conceived and designed the experiments	Conceptualization	YES
4424438	25918446	A.K.	3	Formulated original question|Developed modelling approach|Programmed model|Interpreted results|Wrote first draft|And revised manuscript	Developed modelling approach	Performed the experiments	Methodology	YES
4424438	25918446	A.K.	3	Formulated original question|Developed modelling approach|Programmed model|Interpreted results|Wrote first draft|And revised manuscript	Programmed model	Performed the experiments|Contributed reagents/materials/analysis tools	Methodology|Software	YES
4424438	25918446	A.K.	3	Formulated original question|Developed modelling approach|Programmed model|Interpreted results|Wrote first draft|And revised manuscript	Interpreted results	Analyzed the data	Formal analysis	YES
4424438	25918446	A.K.	3	Formulated original question|Developed modelling approach|Programmed model|Interpreted results|Wrote first draft|And revised manuscript	Wrote first draft	Wrote the paper	Writing - Original Draft	YES
4424438	25918446	A.K.	3	Formulated original question|Developed modelling approach|Programmed model|Interpreted results|Wrote first draft|And revised manuscript	And revised manuscript	Wrote the paper	Writing - Review & Editing	YES
4424438	25918446	C.C.	3	Developed modelling approach|Interpreted results|And revised manuscript	Developed modelling approach	Performed the experiments	Methodology	YES
4424438	25918446	C.C.	3	Developed modelling approach|Interpreted results|And revised manuscript	Interpreted results	Analyzed the data	Formal analysis	YES
4424438	25918446	C.C.	3	Developed modelling approach|Interpreted results|And revised manuscript	And revised manuscript	Wrote the paper	Writing - Review & Editing	YES
4424438	25918446	M.L.	3	Interpreted results|And revised manuscript	Interpreted results	Analyzed the data	Formal analysis	YES
4424438	25918446	M.L.	3	Interpreted results|And revised manuscript	And revised manuscript	Wrote the paper	Writing - Review & Editing	YES
4424438	25918446	T.C.	3	Formulated original question|Developed modelling approach|Interpreted results|And revised manuscript	Formulated original question	Conceived and designed the experiments	Conceptualization	YES
4424438	25918446	T.C.	3	Formulated original question|Developed modelling approach|Interpreted results|And revised manuscript	Developed modelling approach	Performed the experiments	Methodology	YES
4424438	25918446	T.C.	3	Formulated original question|Developed modelling approach|Interpreted results|And revised manuscript	Interpreted results	Analyzed the data	Formal analysis	YES
4424438	25918446	T.C.	3	Formulated original question|Developed modelling approach|Interpreted results|And revised manuscript	And revised manuscript	Wrote the paper	Writing - Review & Editing	YES
5438328	28532121	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5412863	28320736	BMH	2	link to sog1-1|performed the cell death experiments with cycd3|seen and commented by all authors	link to sog1-1	-	-	NO
5412863	28320736	BMH	2	link to sog1-1|performed the cell death experiments with cycd3|seen and commented by all authors	performed the cell death experiments with cycd3	Performed the experiments	Investigation	YES
5412863	28320736	BMH	2	link to sog1-1|performed the cell death experiments with cycd3|seen and commented by all authors	seen and commented by all authors	-	-	NO
5412863	28320736	BS	2	seen and commented by all authors	seen and commented by all authors	-	-	NO
5412863	28320736	GFS-P	2	performed the cell death experiments with cycd3	performed the cell death experiments with cycd3	Performed the experiments	Investigation	YES
5412863	28320736	LB	2	seen and commented by all authors	seen and commented by all authors	-	-	NO
5412863	28320736	PB	2	seen and commented by all authors	seen and commented by all authors	-	-	NO
5412863	28320736	RBR	2	on atbrca1 promoter	on atbrca1 promoter	-	-	NO
5412863	28320736	ZA	2	performed the cell death experiments with cycd3	performed the cell death experiments with cycd3	Performed the experiments	Investigation	YES
1945087	17726523	AP	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1945087	17726523	CN	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1945087	17726523	FS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1945087	17726523	GC	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1945087	17726523	JM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1945087	17726523	JP	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1945087	17726523	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1945087	17726523	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1945087	17726523	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1945087	17726523	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1945087	17726523	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1945087	17726523	PA	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5776133	29387078	All authors	2	contributed to experimental design and conceived experiments	contributed to experimental design and conceived experiments	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
5776133	29387078	TC	2	performed bioinformatics analyses	performed bioinformatics analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5776133	29387078	XL	2	performed the laboratory experiments and analyzed data	performed the laboratory experiments and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5776133	29387078	YY	2	performed the laboratory experiments and analyzed data|wrote the manuscript and designed figures and schematics	performed the laboratory experiments and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5776133	29387078	YY	2	performed the laboratory experiments and analyzed data|wrote the manuscript and designed figures and schematics	wrote the manuscript and designed figures and schematics	Conceived and designed the experiments|Wrote the paper	Visualization|Writing - Original Draft	YES
5776133	29387078	ZM	2	wrote the manuscript and designed figures and schematics	wrote the manuscript and designed figures and schematics	Conceived and designed the experiments|Wrote the paper	Visualization|Writing - Original Draft	YES
4416025	25927230	AJC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416025	25927230	AJC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416025	25927230	AJC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416025	25927230	AJC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416025	25927230	AJC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416025	25927230	ELH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416025	25927230	ELH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416025	25927230	ELH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416025	25927230	KG	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4416025	25927230	KG	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416025	25927230	RG	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4416025	25927230	RG	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4416025	25927230	RG	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416025	25927230	SM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4416025	25927230	SM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4424439	25918447	All authors	2	participated in the conception of the study, substantially edited the manuscript and gave final approval for publication	participated in the conception of the study, substantially edited the manuscript and gave final approval for publication	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
4424439	25918447	P.K.M.	2	coded the model, carried out the analysis and drafted the initial manuscript	coded the model, carried out the analysis and drafted the initial manuscript	Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5701423	29169318	H.H.Z.	PLoS52	edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5701423	29169318	J.Y.Y.	PLoS52	wrote the manuscript|edited the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5701423	29169318	J.Y.Y.	PLoS52	wrote the manuscript|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5701423	29169318	W.Z.	PLoS52	edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5701423	29169318	X.L.	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5701423	29169318	Y.W.	PLoS52	contributed clinical samples and data	contributed clinical samples and data	Contributed reagents/materials/analysis tools	Resources	YES
5701423	29169318	Y.X.S.	PLoS52	contributed clinical samples and data|analyzed the data|wrote the manuscript|edited the manuscript	contributed clinical samples and data	Contributed reagents/materials/analysis tools	Resources	YES
5701423	29169318	Y.X.S.	PLoS52	contributed clinical samples and data|analyzed the data|wrote the manuscript|edited the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5701423	29169318	Y.X.S.	PLoS52	contributed clinical samples and data|analyzed the data|wrote the manuscript|edited the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5701423	29169318	Y.X.S.	PLoS52	contributed clinical samples and data|analyzed the data|wrote the manuscript|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5701423	29169318	Z.Q.L.	PLoS52	edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5738882	29296106	AB	7	protocol design and data collection	protocol design and data collection	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5738882	29296106	JS	7	protocol design, data analysis, and manuscript preparation	protocol design, data analysis, and manuscript preparation	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5738882	29296106	JSC	7	protocol design and manuscript preparation	protocol design and manuscript preparation	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5776150	29387080	KR	2	constructed the k -mer detection pipelines, wrote in-house python scripts, analyzed the sequence data and wrote the manuscript|designed the experiments and interpreted the results of all analysis	constructed the k -mer detection pipelines, wrote in-house python scripts, analyzed the sequence data and wrote the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Software|Writing - Original Draft	YES
5776150	29387080	KR	2	constructed the k -mer detection pipelines, wrote in-house python scripts, analyzed the sequence data and wrote the manuscript|designed the experiments and interpreted the results of all analysis	designed the experiments and interpreted the results of all analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5776150	29387080	MR	2	designed the experiments and interpreted the results of all analysis|edited the manuscript	designed the experiments and interpreted the results of all analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5776150	29387080	MR	2	designed the experiments and interpreted the results of all analysis|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
4455765	26009775	B.M.	PLoS52	analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
4455765	26009775	C.L.-P.	PLoS52	conceived and performed the experiments|analysed the data	conceived and performed the experiments	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
4455765	26009775	C.L.-P.	PLoS52	conceived and performed the experiments|analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
4455765	26009775	F.F.D.-M.	PLoS52	conceived and performed the experiments|analysed the data|wrote the paper	conceived and performed the experiments	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
4455765	26009775	F.F.D.-M.	PLoS52	conceived and performed the experiments|analysed the data|wrote the paper	analysed the data	Analyzed the data	Formal analysis	YES
4455765	26009775	F.F.D.-M.	PLoS52	conceived and performed the experiments|analysed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4455765	26009775	P.N.	PLoS52	conceived and performed the experiments|analysed the data	conceived and performed the experiments	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
4455765	26009775	P.N.	PLoS52	conceived and performed the experiments|analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
5412881	28320737	LCF	PLoS52	performed the experiments|designed the experiments and wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5412881	28320737	LCF	PLoS52	performed the experiments|designed the experiments and wrote the manuscript	designed the experiments and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5412881	28320737	SMC	PLoS52	designed the experiments and wrote the manuscript	designed the experiments and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5412881	28320737	SS	PLoS52	contributed to producing the mir-31a rmce allele	contributed to producing the mir-31a rmce allele	-	-	NO
1945088	17712407	AM	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1945088	17712407	AM	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1945088	17712407	BL	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1945088	17712407	BL	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5442031	28545259	AI	2	did isolation of active substance from the methanolic extract, and also evaluated diacetonamine and its related compounds for sporulation induction	did isolation of active substance from the methanolic extract, and also evaluated diacetonamine and its related compounds for sporulation induction	Performed the experiments	Investigation	YES
5442031	28545259	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5442031	28545259	DK	2	assisted it	assisted it	-	-	NO
5442031	28545259	SIF	2	in the extract of soybean curd residue as diacetonamine	in the extract of soybean curd residue as diacetonamine	-	-	NO
4416026	25927703	AG	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416026	25927703	GK	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416026	25927703	GS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416026	25927703	GS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416026	25927703	GS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416026	25927703	JT	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416026	25927703	MM	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416026	25927703	NS	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416026	25927703	NS	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5702050	29178823	CMG	PLoS52	conceived and designed the research|analyzed the data|wrote the manuscript	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5702050	29178823	CMG	PLoS52	conceived and designed the research|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5702050	29178823	CMG	PLoS52	conceived and designed the research|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5702050	29178823	DS	PLoS52	conceived and designed the research	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5702050	29178823	JB	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5702050	29178823	JP	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5702050	29178823	KH	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5702050	29178823	KMS	PLoS52	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5702050	29178823	MA	PLoS52	analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5702050	29178823	MA	PLoS52	analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5702050	29178823	MM	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5702050	29178823	MR	PLoS52	conceived and designed the research|analyzed the data	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5702050	29178823	MR	PLoS52	conceived and designed the research|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5702050	29178823	MSIB	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5702050	29178823	OCS	PLoS52	conceived and designed the research|analyzed the data|wrote the manuscript	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5702050	29178823	OCS	PLoS52	conceived and designed the research|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5702050	29178823	OCS	PLoS52	conceived and designed the research|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5702050	29178823	RBS	PLoS52	conceived and designed the research	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5702050	29178823	SL	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5702050	29178823	SM	PLoS52	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5702050	29178823	SUR	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5702050	29178823	TTM	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5702050	29178823	ZR	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5755346	29311763	ARJ	2	designed the study, oversaw data collection, analysis and manuscript preparation	designed the study, oversaw data collection, analysis and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Supervision|Writing - Original Draft	YES
5755346	29311763	CLC	2	assisted with data analysis, interpretation of results and manuscript preparation	assisted with data analysis, interpretation of results and manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5755346	29311763	JE	2	assisted with interpretation of results and manuscript preparation	assisted with interpretation of results and manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5755346	29311763	MC	2	coordinated data collection, assisted with data analysis and manuscript preparation	coordinated data collection, assisted with data analysis and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Project administration|Writing - Original Draft	YES
5755346	29311763	SD	2	assisted with interpretation of results	assisted with interpretation of results	Analyzed the data	Formal analysis	YES
5778104	29403511	All authors	2	were involved into the writing of this review manuscript	were involved into the writing of this review manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4527383	25964450	A.M.E.	2	conceived the study|designed the study|contributed to discussion and interpretation of the results|participated in writing the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4527383	25964450	A.M.E.	2	conceived the study|designed the study|contributed to discussion and interpretation of the results|participated in writing the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
4527383	25964450	A.M.E.	2	conceived the study|designed the study|contributed to discussion and interpretation of the results|participated in writing the manuscript	contributed to discussion and interpretation of the results	Analyzed the data	Formal analysis	YES
4527383	25964450	A.M.E.	2	conceived the study|designed the study|contributed to discussion and interpretation of the results|participated in writing the manuscript	participated in writing the manuscript	Wrote the paper	Writing - Original Draft	YES
4527383	25964450	E.L.W.	2	drafted the manuscript and coordinated the writing of the manuscript|contributed to discussion and interpretation of the results|participated in writing the manuscript	drafted the manuscript and coordinated the writing of the manuscript	Wrote the paper	Project administration|Writing - Original Draft	YES
4527383	25964450	E.L.W.	2	drafted the manuscript and coordinated the writing of the manuscript|contributed to discussion and interpretation of the results|participated in writing the manuscript	contributed to discussion and interpretation of the results	Analyzed the data	Formal analysis	YES
4527383	25964450	E.L.W.	2	drafted the manuscript and coordinated the writing of the manuscript|contributed to discussion and interpretation of the results|participated in writing the manuscript	participated in writing the manuscript	Wrote the paper	Writing - Original Draft	YES
4527383	25964450	G.N.	2	conducted the t-spot	conducted the t-spot	Performed the experiments	Investigation	YES
4527383	25964450	H.M.D.	2	contributed to discussion and interpretation of the results|participated in writing the manuscript	contributed to discussion and interpretation of the results	Analyzed the data	Formal analysis	YES
4527383	25964450	H.M.D.	2	contributed to discussion and interpretation of the results|participated in writing the manuscript	participated in writing the manuscript	Wrote the paper	Writing - Original Draft	YES
4527383	25964450	M.A.	2	participated in recruitment and study monitoring	participated in recruitment and study monitoring	Performed the experiments	Investigation|Supervision	YES
4527383	25964450	M.E.	2	participated in the flow cytometry assays and analysis	participated in the flow cytometry assays and analysis	Performed the experiments	Investigation	YES
4527383	25964450	M.M.	2	participated in writing the manuscript	participated in writing the manuscript	Wrote the paper	Writing - Original Draft	YES
4527383	25964450	P.A.M.	2	designed the study|contributed to discussion and interpretation of the results|participated in writing the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
4527383	25964450	P.A.M.	2	designed the study|contributed to discussion and interpretation of the results|participated in writing the manuscript	contributed to discussion and interpretation of the results	Analyzed the data	Formal analysis	YES
4527383	25964450	P.A.M.	2	designed the study|contributed to discussion and interpretation of the results|participated in writing the manuscript	participated in writing the manuscript	Wrote the paper	Writing - Original Draft	YES
4527383	25964450	S.C.	2	designed the study|contributed to discussion and interpretation of the results|participated in writing the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
4527383	25964450	S.C.	2	designed the study|contributed to discussion and interpretation of the results|participated in writing the manuscript	contributed to discussion and interpretation of the results	Analyzed the data	Formal analysis	YES
4527383	25964450	S.C.	2	designed the study|contributed to discussion and interpretation of the results|participated in writing the manuscript	participated in writing the manuscript	Wrote the paper	Writing - Original Draft	YES
4527383	25964450	S.G.S.	2	contributed to discussion and interpretation of the results|participated in writing the manuscript	contributed to discussion and interpretation of the results	Analyzed the data	Formal analysis	YES
4527383	25964450	S.G.S.	2	contributed to discussion and interpretation of the results|participated in writing the manuscript	participated in writing the manuscript	Wrote the paper	Writing - Original Draft	YES
4416030	25928359	DBM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416030	25928359	DBM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416030	25928359	DBM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416030	25928359	DBM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416030	25928359	DNS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416030	25928359	DNS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416030	25928359	DR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416030	25928359	DR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416030	25928359	DR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4628718	26557698	Batanai Moyo	2	performed the experiments, analysed and interpreted the data, and wrote the paper	performed the experiments, analysed and interpreted the data, and wrote the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4628718	26557698	Stanley Mukanganyama	2	directed the research, collected the plant material, analysed and interpreted the data, and edited the paper	directed the research, collected the plant material, analysed and interpreted the data, and edited the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Supervision|Writing - Review & Editing	YES
1945089	17712421	CK	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1945089	17712421	CK	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1945089	17712421	GA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1945089	17712421	GA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1945089	17712421	GA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1945089	17712421	GA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1945089	17712421	KD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1945089	17712421	KD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1945089	17712421	KD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1945089	17712421	KD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1945089	17712421	KD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1945089	17712421	MS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1945089	17712421	MS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1945089	17712421	MS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1945089	17712421	MS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1945089	17712421	RR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1945089	17712421	RR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1945089	17712421	RR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1945089	17712421	RR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5442039	28545260	All authors	2	read and approval the final manuscript	read and approval the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5442039	28545260	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5702081	29178829	DT	2	wrote the encore software and analyzed screening results|wrote the manuscript and walkthrough	wrote the encore software and analyzed screening results	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Software|Writing - Original Draft	YES
5702081	29178829	DT	2	wrote the encore software and analyzed screening results|wrote the manuscript and walkthrough	wrote the manuscript and walkthrough	Wrote the paper	Writing - Original Draft	YES
5702081	29178829	HS	2	designed statistics tests and implementation	designed statistics tests and implementation	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5702081	29178829	JS	2	wrote the manuscript and walkthrough	wrote the manuscript and walkthrough	Wrote the paper	Writing - Original Draft	YES
5702081	29178829	MP	2	wrote the encore software and analyzed screening results|wrote the manuscript and walkthrough	wrote the encore software and analyzed screening results	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Software|Writing - Original Draft	YES
5702081	29178829	MP	2	wrote the encore software and analyzed screening results|wrote the manuscript and walkthrough	wrote the manuscript and walkthrough	Wrote the paper	Writing - Original Draft	YES
5702081	29178829	SD	2	performed the tnfa screen and analyzed results	performed the tnfa screen and analyzed results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5702081	29178829	SP	2	performed all cell based experiments and analyses	performed all cell based experiments and analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5702081	29178829	WW	2	assisted in software design and implementation	assisted in software design and implementation	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5756374	29311764	E.C.	2	selected the articles included|analyzed the articles included|prepared the figures and tables and drafted the manuscript|edited and revised manuscript|the final version of the manuscript	selected the articles included	-	-	NO
5756374	29311764	E.C.	2	selected the articles included|analyzed the articles included|prepared the figures and tables and drafted the manuscript|edited and revised manuscript|the final version of the manuscript	analyzed the articles included	Analyzed the data	Formal analysis	YES
5756374	29311764	E.C.	2	selected the articles included|analyzed the articles included|prepared the figures and tables and drafted the manuscript|edited and revised manuscript|the final version of the manuscript	prepared the figures and tables and drafted the manuscript	Wrote the paper	Visualization|Writing - Original Draft	YES
5756374	29311764	E.C.	2	selected the articles included|analyzed the articles included|prepared the figures and tables and drafted the manuscript|edited and revised manuscript|the final version of the manuscript	edited and revised manuscript	Wrote the paper	Writing - Review & Editing	YES
5756374	29311764	E.C.	2	selected the articles included|analyzed the articles included|prepared the figures and tables and drafted the manuscript|edited and revised manuscript|the final version of the manuscript	the final version of the manuscript	-	-	NO
5756374	29311764	F.M.-O.	2	selected the articles included|edited and revised manuscript|the final version of the manuscript	selected the articles included	-	-	NO
5756374	29311764	F.M.-O.	2	selected the articles included|edited and revised manuscript|the final version of the manuscript	edited and revised manuscript	Wrote the paper	Writing - Review & Editing	YES
5756374	29311764	F.M.-O.	2	selected the articles included|edited and revised manuscript|the final version of the manuscript	the final version of the manuscript	-	-	NO
5756374	29311764	J.L.M.-M.	2	prepared the figures and tables and drafted the manuscript|edited and revised manuscript|the final version of the manuscript	prepared the figures and tables and drafted the manuscript	Wrote the paper	Visualization|Writing - Original Draft	YES
5756374	29311764	J.L.M.-M.	2	prepared the figures and tables and drafted the manuscript|edited and revised manuscript|the final version of the manuscript	edited and revised manuscript	Wrote the paper	Writing - Review & Editing	YES
5756374	29311764	J.L.M.-M.	2	prepared the figures and tables and drafted the manuscript|edited and revised manuscript|the final version of the manuscript	the final version of the manuscript	-	-	NO
5756374	29311764	M.C.L.-E.	2	analyzed the articles included|edited and revised manuscript|the final version of the manuscript	analyzed the articles included	Analyzed the data	Formal analysis	YES
5756374	29311764	M.C.L.-E.	2	analyzed the articles included|edited and revised manuscript|the final version of the manuscript	edited and revised manuscript	Wrote the paper	Writing - Review & Editing	YES
5756374	29311764	M.C.L.-E.	2	analyzed the articles included|edited and revised manuscript|the final version of the manuscript	the final version of the manuscript	-	-	NO
5756374	29311764	M.V.G.-C.	2	prepared the figures and tables and drafted the manuscript|edited and revised manuscript|the final version of the manuscript	prepared the figures and tables and drafted the manuscript	Wrote the paper	Visualization|Writing - Original Draft	YES
5756374	29311764	M.V.G.-C.	2	prepared the figures and tables and drafted the manuscript|edited and revised manuscript|the final version of the manuscript	edited and revised manuscript	Wrote the paper	Writing - Review & Editing	YES
5756374	29311764	M.V.G.-C.	2	prepared the figures and tables and drafted the manuscript|edited and revised manuscript|the final version of the manuscript	the final version of the manuscript	-	-	NO
5756374	29311764	M.V.G.-G.	2	conceived and designed the review	conceived and designed the review	Conceived and designed the experiments	Conceptualization	YES
5756374	29311764	P.G.-F.	2	selected the articles included|edited and revised manuscript|the final version of the manuscript	selected the articles included	-	-	NO
5756374	29311764	P.G.-F.	2	selected the articles included|edited and revised manuscript|the final version of the manuscript	edited and revised manuscript	Wrote the paper	Writing - Review & Editing	YES
5756374	29311764	P.G.-F.	2	selected the articles included|edited and revised manuscript|the final version of the manuscript	the final version of the manuscript	-	-	NO
5756374	29311764	P.V.-H.	2	analyzed the articles included|edited and revised manuscript|the final version of the manuscript	analyzed the articles included	Analyzed the data	Formal analysis	YES
5756374	29311764	P.V.-H.	2	analyzed the articles included|edited and revised manuscript|the final version of the manuscript	edited and revised manuscript	Wrote the paper	Writing - Review & Editing	YES
5756374	29311764	P.V.-H.	2	analyzed the articles included|edited and revised manuscript|the final version of the manuscript	the final version of the manuscript	-	-	NO
5756374	29311764	R.D.	2	conceived and designed the review|prepared the figures and tables and drafted the manuscript|edited and revised manuscript|the final version of the manuscript	conceived and designed the review	Conceived and designed the experiments	Conceptualization	YES
5756374	29311764	R.D.	2	conceived and designed the review|prepared the figures and tables and drafted the manuscript|edited and revised manuscript|the final version of the manuscript	prepared the figures and tables and drafted the manuscript	Wrote the paper	Visualization|Writing - Original Draft	YES
5756374	29311764	R.D.	2	conceived and designed the review|prepared the figures and tables and drafted the manuscript|edited and revised manuscript|the final version of the manuscript	edited and revised manuscript	Wrote the paper	Writing - Review & Editing	YES
5756374	29311764	R.D.	2	conceived and designed the review|prepared the figures and tables and drafted the manuscript|edited and revised manuscript|the final version of the manuscript	the final version of the manuscript	-	-	NO
5756374	29311764	S.F.S.	2	prepared the figures and tables and drafted the manuscript|edited and revised manuscript|the final version of the manuscript	prepared the figures and tables and drafted the manuscript	Wrote the paper	Visualization|Writing - Original Draft	YES
5756374	29311764	S.F.S.	2	prepared the figures and tables and drafted the manuscript|edited and revised manuscript|the final version of the manuscript	edited and revised manuscript	Wrote the paper	Writing - Review & Editing	YES
5756374	29311764	S.F.S.	2	prepared the figures and tables and drafted the manuscript|edited and revised manuscript|the final version of the manuscript	the final version of the manuscript	-	-	NO
4416031	25927683	CCU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416031	25927683	CCU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416031	25927683	CCU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416031	25927683	CCU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416031	25927683	HGD	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416031	25927683	HSPG	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416031	25927683	SAD	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416031	25927683	SL	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4416031	25927683	SL	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5778123	29403506	BC	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5778123	29403506	CG	PLoS52	analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5778123	29403506	CG	PLoS52	analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5778123	29403506	DZ	PLoS52	planned and designed the research|analyzed the data	planned and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5778123	29403506	DZ	PLoS52	planned and designed the research|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5778123	29403506	MQ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5778123	29403506	QD	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5430213	28320741	EEO	2	designed the study|analyzed the data and wrote the first version of the manuscript|reviewed and revised the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5430213	28320741	EEO	2	designed the study|analyzed the data and wrote the first version of the manuscript|reviewed and revised the manuscript	analyzed the data and wrote the first version of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5430213	28320741	EEO	2	designed the study|analyzed the data and wrote the first version of the manuscript|reviewed and revised the manuscript	reviewed and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5430213	28320741	ESG	2	designed the study|performed the in vitro experiments|performed the transcriptomic analysis|analyzed the data and wrote the first version of the manuscript|reviewed and revised the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5430213	28320741	ESG	2	designed the study|performed the in vitro experiments|performed the transcriptomic analysis|analyzed the data and wrote the first version of the manuscript|reviewed and revised the manuscript	performed the in vitro experiments	Performed the experiments	Investigation	YES
5430213	28320741	ESG	2	designed the study|performed the in vitro experiments|performed the transcriptomic analysis|analyzed the data and wrote the first version of the manuscript|reviewed and revised the manuscript	performed the transcriptomic analysis	Performed the experiments	Investigation	YES
5430213	28320741	ESG	2	designed the study|performed the in vitro experiments|performed the transcriptomic analysis|analyzed the data and wrote the first version of the manuscript|reviewed and revised the manuscript	analyzed the data and wrote the first version of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5430213	28320741	ESG	2	designed the study|performed the in vitro experiments|performed the transcriptomic analysis|analyzed the data and wrote the first version of the manuscript|reviewed and revised the manuscript	reviewed and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5430213	28320741	EZO	2	performed the in vitro experiments	performed the in vitro experiments	Performed the experiments	Investigation	YES
5430213	28320741	HCT	2	performed the in vitro experiments	performed the in vitro experiments	Performed the experiments	Investigation	YES
5430213	28320741	KRC	2	performed the transcriptomic analysis	performed the transcriptomic analysis	Performed the experiments	Investigation	YES
5430213	28320741	MRW	2	performed the lipid profiling|reviewed and revised the manuscript	performed the lipid profiling	Performed the experiments	Investigation	YES
5430213	28320741	MRW	2	performed the lipid profiling|reviewed and revised the manuscript	reviewed and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5430213	28320741	SG	2	performed the chip-seq analysis	performed the chip-seq analysis	Performed the experiments	Investigation	YES
5430213	28320741	WFC	2	performed the lipid profiling|reviewed and revised the manuscript	performed the lipid profiling	Performed the experiments	Investigation	YES
5430213	28320741	WFC	2	performed the lipid profiling|reviewed and revised the manuscript	reviewed and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5430213	28320741	XC	2	performed the chip-seq analysis	performed the chip-seq analysis	Performed the experiments	Investigation	YES
4527394	25964461	Both authors	2	contributed to conceptual development and wrote the manuscript	contributed to conceptual development and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
1945090	17712403	GD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1945090	17712403	GD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1945090	17712403	GD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1945090	17712403	GD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1945090	17712403	LB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1945090	17712403	LB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1945090	17712403	LB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1945090	17712403	LB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1945090	17712403	LR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1945090	17712403	LR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1945090	17712403	LR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1945090	17712403	LR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416032	25927524	DC	PLoS5	Conceived and designed the experiments|Wrote the paper|Coordinated the study	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416032	25927524	DC	PLoS5	Conceived and designed the experiments|Wrote the paper|Coordinated the study	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416032	25927524	DC	PLoS5	Conceived and designed the experiments|Wrote the paper|Coordinated the study	Coordinated the study	-	Project administration	YES
4416032	25927524	FA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416032	25927524	FA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416032	25927524	FA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416032	25927524	FA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416032	25927524	JR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416032	25927524	JR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416032	25927524	JR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416032	25927524	JW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416032	25927524	LK	PLoS5	Conceived and designed the experiments|Wrote the paper|Coordinated the study	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416032	25927524	LK	PLoS5	Conceived and designed the experiments|Wrote the paper|Coordinated the study	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416032	25927524	LK	PLoS5	Conceived and designed the experiments|Wrote the paper|Coordinated the study	Coordinated the study	-	Project administration	YES
4416032	25927524	WL	PLoS5	Conceived and designed the experiments|Analyzed the data|Coordinated the study	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416032	25927524	WL	PLoS5	Conceived and designed the experiments|Analyzed the data|Coordinated the study	Analyzed the data	Analyzed the data	Formal analysis	YES
4416032	25927524	WL	PLoS5	Conceived and designed the experiments|Analyzed the data|Coordinated the study	Coordinated the study	-	Project administration	YES
4416032	25927524	XC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416032	25927524	ZZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416032	25927524	ZZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416032	25927524	ZZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416032	25927524	ZZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5442072	28545261	All	2	relevant data are presented in the manuscript	relevant data are presented in the manuscript	-	-	NO
5442072	28545261	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5442072	28545261	Andrea Windisch	2	for excellent technical assistance	for excellent technical assistance	Performed the experiments	Investigation	YES
5442072	28545261	JM	2	performance of microbiological experiments, writing of the paper	performance of microbiological experiments, writing of the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5442072	28545261	MN	2	writing of the paper, guidance of the study, statistical analysis	writing of the paper, guidance of the study, statistical analysis	Analyzed the data|Wrote the paper	Formal analysis|Supervision|Writing - Original Draft	YES
5442072	28545261	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5442072	28545261	VX	2	idea and concept, performance and guidance of biochemical experiments, writing of the paper	idea and concept, performance and guidance of biochemical experiments, writing of the paper	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Supervision|Writing - Original Draft	YES
5702100	29178833	AB	2	contributed data and helped in the analyses	contributed data and helped in the analyses	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5702100	29178833	BB	2	conceived the study, carried out all analyses and wrote the manuscript	conceived the study, carried out all analyses and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
5702100	29178833	BG	2	conceived the study, carried out all analyses and wrote the manuscript	conceived the study, carried out all analyses and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
5702100	29178833	CF	2	conceived the study, carried out all analyses and wrote the manuscript	conceived the study, carried out all analyses and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
5702100	29178833	CS	2	contributed data and helped in the analyses	contributed data and helped in the analyses	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5702100	29178833	DG	2	contributed data and helped in the analyses	contributed data and helped in the analyses	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5702100	29178833	FRS	2	conceived the study, carried out all analyses and wrote the manuscript	conceived the study, carried out all analyses and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
5702100	29178833	HSH	2	contributed data and helped in the analyses	contributed data and helped in the analyses	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5702100	29178833	IC	2	contributed data and helped in the analyses	contributed data and helped in the analyses	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5702100	29178833	IR	2	contributed data and helped in the analyses|contributed data and helped in the analyses	contributed data and helped in the analyses	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5702100	29178833	IR	2	contributed data and helped in the analyses|contributed data and helped in the analyses	contributed data and helped in the analyses	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5702100	29178833	JS	2	contributed data and helped in the analyses	contributed data and helped in the analyses	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5702100	29178833	MF	2	conceived the study, carried out all analyses and wrote the manuscript	conceived the study, carried out all analyses and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
5702100	29178833	MGS	2	contributed data and helped in the analyses	contributed data and helped in the analyses	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5702100	29178833	RF	2	contributed data and helped in the analyses	contributed data and helped in the analyses	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5452015	28408439	BL	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5452015	28408439	DL	2	initiated the project	initiated the project	Conceived and designed the experiments	Conceptualization	YES
5452015	28408439	EC	2	initiated the project|wrote the manuscript	initiated the project	Conceived and designed the experiments	Conceptualization	YES
5452015	28408439	EC	2	initiated the project|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5452015	28408439	FB	2	carried out the rnase protection assays	carried out the rnase protection assays	Performed the experiments	Investigation	YES
5452015	28408439	JB	2	purified all proteins	purified all proteins	Performed the experiments	Investigation	YES
5452015	28408439	OP	2	initiated the project|wrote the manuscript	initiated the project	Conceived and designed the experiments	Conceptualization	YES
5452015	28408439	OP	2	initiated the project|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5452015	28408439	ZH	2	carried out the enzymatic assays and in vivo analysis	carried out the enzymatic assays and in vivo analysis	Performed the experiments	Investigation	YES
4528416	26194753	E.L.P.	2	wrote the manuscript together, worked on several drafts and revisions, conceived of the original ideas in the review and both authors approve of the final version to be published	wrote the manuscript together, worked on several drafts and revisions, conceived of the original ideas in the review and both authors approve of the final version to be published	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
4528416	26194753	U.H.	2	wrote the manuscript together, worked on several drafts and revisions, conceived of the original ideas in the review and both authors approve of the final version to be published	wrote the manuscript together, worked on several drafts and revisions, conceived of the original ideas in the review and both authors approve of the final version to be published	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
4628721	26557705	JunJ	2	contributed to this work by taking part in designing the experimental plan and analysis of these data	contributed to this work by taking part in designing the experimental plan and analysis of these data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Methodology|Resources	YES
1949048	17726527	AM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1949048	17726527	DC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1949048	17726527	DC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1949048	17726527	DC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1949048	17726527	GM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1949048	17726527	JM	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1949048	17726527	LD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1949048	17726527	LD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1949048	17726527	LD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1949048	17726527	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1949048	17726527	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1949048	17726527	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1949048	17726527	SP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1949048	17726527	SP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1949048	17726527	SP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1949048	17726527	SP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1949048	17726527	TG	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1949048	17726527	TG	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1949048	17726527	VV	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1949048	17726527	VV	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1949048	17726527	YS	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1949048	17726527	YS	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5769537	29371857	AC	2	conceived the study|participated in the design of the study|carried out the data collection, nutritional and statistical analysis|helped to draft the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5769537	29371857	AC	2	conceived the study|participated in the design of the study|carried out the data collection, nutritional and statistical analysis|helped to draft the manuscript	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
5769537	29371857	AC	2	conceived the study|participated in the design of the study|carried out the data collection, nutritional and statistical analysis|helped to draft the manuscript	carried out the data collection, nutritional and statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5769537	29371857	AC	2	conceived the study|participated in the design of the study|carried out the data collection, nutritional and statistical analysis|helped to draft the manuscript	helped to draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5769537	29371857	MB	2	helped to draft the manuscript	helped to draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5769537	29371857	TS	2	participated in the design of the study|helped to draft the manuscript	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
5769537	29371857	TS	2	participated in the design of the study|helped to draft the manuscript	helped to draft the manuscript	Wrote the paper	Writing - Original Draft	YES
4416033	25928229	HC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416033	25928229	JW	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4416033	25928229	JW	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416033	25928229	KM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416033	25928229	KM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416033	25928229	KM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416033	25928229	MF	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416033	25928229	MF	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416033	25928229	SS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416033	25928229	SS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416033	25928229	SS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416033	25928229	SW	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416033	25928229	SW	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416033	25928229	VC	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4416033	25928229	VC	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416033	25928229	XL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5445031	28549374	All	2	data is shown in graphs, figures and tables	data is shown in graphs, figures and tables	-	Visualization	YES
5445031	28549374	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5445031	28549374	DG	2	planned and carried out the experiments, analyzed the data and wrote the manuscript	planned and carried out the experiments, analyzed the data and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
5445031	28549374	HP	2	planned and carried out the experiments, analyzed the data and wrote the manuscript	planned and carried out the experiments, analyzed the data and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
5445031	28549374	LZ	2	planned and carried out the experiments, analyzed the data and wrote the manuscript	planned and carried out the experiments, analyzed the data and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
5445031	28549374	QL	2	planned and carried out the experiments, analyzed the data and wrote the manuscript	planned and carried out the experiments, analyzed the data and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
5445031	28549374	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5445031	28549374	XL	2	reviewed the manuscript, participated in the data analysis and finalized the manuscript	reviewed the manuscript, participated in the data analysis and finalized the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5778143	29403518	AM	7	Provided the recombinant inbred line population, performed the genetic analysis, and complemented the writing on the genetic topics	Provided the recombinant inbred line population, performed the genetic analysis, and complemented the writing on the genetic topics	Performed the experiments|Wrote the paper	Investigation	YES
5778143	29403518	FG	7	Conceived the project, designed the field and pot experiments, analyzed the pertaining data and wrote the article with contributions of all authors	Conceived the project, designed the field and pot experiments, analyzed the pertaining data and wrote the article with contributions of all authors	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5778143	29403518	GS	7	Supervised the field and pot experiment and acquired field and pot data	Supervised the field and pot experiment and acquired field and pot data	Performed the experiments	Investigation|Supervision	YES
5778143	29403518	PD	7	Provided the recombinant inbred line population, performed the genetic analysis, and complemented the writing on the genetic topics	Provided the recombinant inbred line population, performed the genetic analysis, and complemented the writing on the genetic topics	Performed the experiments|Wrote the paper	Investigation	YES
5778143	29403518	RM	7	Conceived the project, designed the field and pot experiments, analyzed the pertaining data and wrote the article with contributions of all authors	Conceived the project, designed the field and pot experiments, analyzed the pertaining data and wrote the article with contributions of all authors	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5702118	29178824	ML	PLoS52	contributed reagents/materials/analysis tools	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5702118	29178824	XN	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5702118	29178824	XN	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5702118	29178824	XN	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5702118	29178824	XN	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5702118	29178824	XZ	PLoS52	conceived and designed the experiments|contributed reagents/materials/analysis tools	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5702118	29178824	XZ	PLoS52	conceived and designed the experiments|contributed reagents/materials/analysis tools	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5702118	29178824	YWa	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5702118	29178824	YWu	PLoS52	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5778267	29403515	GL	2	designed the research|wrote the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
5778267	29403515	GL	2	designed the research|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5778267	29403515	HZ	2	designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
5778267	29403515	QS	2	designed the research|performed the most of experiments and analyzed data|wrote the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
5778267	29403515	QS	2	designed the research|performed the most of experiments and analyzed data|wrote the manuscript	performed the most of experiments and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5778267	29403515	QS	2	designed the research|performed the most of experiments and analyzed data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5778267	29403515	RL	2	designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
5778267	29403515	XS	2	designed the research|performed the most of experiments and analyzed data	designed the research	Conceived and designed the experiments	Methodology	YES
5778267	29403515	XS	2	designed the research|performed the most of experiments and analyzed data	performed the most of experiments and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5778267	29403515	YJ	2	designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
5470046	28377462	AAH	2	shared important insights and ideas|provided important resources	shared important insights and ideas	Conceived and designed the experiments	Conceptualization	YES
5470046	28377462	AAH	2	shared important insights and ideas|provided important resources	provided important resources	Contributed reagents/materials/analysis tools	Resources	YES
5470046	28377462	AK	2	purified and characterized wild-type and mutant ubc9	purified and characterized wild-type and mutant ubc9	Performed the experiments	Investigation	YES
5470046	28377462	AP	2	performed the fus in vitro aging assay with the	performed the fus in vitro aging assay with the	Performed the experiments	Investigation	YES
5470046	28377462	DM	2	performed all cell culture experiments and performed all image analysis|wrote the manuscript	performed all cell culture experiments and performed all image analysis	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
5470046	28377462	DM	2	performed all cell culture experiments and performed all image analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5470046	28377462	EEB	2	purified and characterized wild-type and mutant ubc9	purified and characterized wild-type and mutant ubc9	Performed the experiments	Investigation	YES
5470046	28377462	HOL	2	constructed bac cell lines and shared ideas	constructed bac cell lines and shared ideas	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5470046	28377462	SA	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5470046	28377462	SC	2	shared important insights and ideas	shared important insights and ideas	Conceived and designed the experiments	Conceptualization	YES
5470046	28377462	SM	2	performed rnase microinjection	performed rnase microinjection	Performed the experiments	Investigation	YES
5470046	28377462	TMF	2	purified and characterized wild-type and mutant ubc9|helped with the performed the fus in vitro aging assay with the	purified and characterized wild-type and mutant ubc9	Performed the experiments	Investigation	YES
5470046	28377462	TMF	2	purified and characterized wild-type and mutant ubc9|helped with the performed the fus in vitro aging assay with the	helped with the performed the fus in vitro aging assay with the	Performed the experiments	Investigation	YES
4416034	25927530	ABF	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416034	25927530	ABF	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416034	25927530	DSM	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416034	25927530	DSM	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416034	25927530	LL	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416034	25927530	LL	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416034	25927530	MJS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416034	25927530	MJS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416034	25927530	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416034	25927530	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416034	25927530	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416034	25927530	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416034	25927530	SN	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416034	25927530	SN	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416034	25927530	WZ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416034	25927530	WZ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416034	25927530	WZ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5781260	29410606	All authors	2	contributed to the study design and data interpretation	contributed to the study design and data interpretation	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Methodology|Resources	YES
5781260	29410606	CAR	2	undertook management of the study, including study execution, overseeing data collection, management, quality assurance and analyses|wrote the first draft of this paper and all authors were responsible for subsequent critical revision of the manuscript	undertook management of the study, including study execution, overseeing data collection, management, quality assurance and analyses	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation|Project administration|Supervision|Validation	YES
5781260	29410606	CAR	2	undertook management of the study, including study execution, overseeing data collection, management, quality assurance and analyses|wrote the first draft of this paper and all authors were responsible for subsequent critical revision of the manuscript	wrote the first draft of this paper and all authors were responsible for subsequent critical revision of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5781260	29410606	CS	2	undertook management of the study, including study execution, overseeing data collection, management, quality assurance and analyses	undertook management of the study, including study execution, overseeing data collection, management, quality assurance and analyses	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation|Project administration|Supervision|Validation	YES
5781260	29410606	ES	2	undertook management of the study, including study execution, overseeing data collection, management, quality assurance and analyses	undertook management of the study, including study execution, overseeing data collection, management, quality assurance and analyses	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation|Project administration|Supervision|Validation	YES
5781260	29410606	SBW	2	wrote the first draft of this paper and all authors were responsible for subsequent critical revision of the manuscript|is the corresponding author for this paper	wrote the first draft of this paper and all authors were responsible for subsequent critical revision of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5781260	29410606	SBW	2	wrote the first draft of this paper and all authors were responsible for subsequent critical revision of the manuscript|is the corresponding author for this paper	is the corresponding author for this paper	-	-	NO
1949049	17726528	DS	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1949049	17726528	GK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1949049	17726528	HF	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1949049	17726528	HF	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1949049	17726528	ST	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1949049	17726528	TE	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1949049	17726528	TT	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1949049	17726528	VK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5702132	29178830	AS	2	wrote the manuscript|supervised the study	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5702132	29178830	AS	2	wrote the manuscript|supervised the study	supervised the study	-	Supervision	YES
5702132	29178830	JAG	2	performed analysis|wrote the manuscript	performed analysis	Performed the experiments	Investigation	YES
5702132	29178830	JAG	2	performed analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5702132	29178830	JCM	2	wrote the manuscript|supervised the study	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5702132	29178830	JCM	2	wrote the manuscript|supervised the study	supervised the study	-	Supervision	YES
5445041	28549373	AR	2	participated in the plant analysis	participated in the plant analysis	Performed the experiments	Investigation	YES
5445041	28549373	All	2	data is shown in tables within the article	data is shown in tables within the article	-	-	NO
5445041	28549373	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5445041	28549373	BEL	2	reviewed and finalized the manuscript	reviewed and finalized the manuscript	Wrote the paper	Writing - Review & Editing	YES
5445041	28549373	EFP	2	analyzed the fermentation data	analyzed the fermentation data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5445041	28549373	MV	2	planned, carried out the immobilization and fermentation experiments, and wrote the manuscript	planned, carried out the immobilization and fermentation experiments, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
5445041	28549373	NV	2	planned, carried out the immobilization and fermentation experiments, and wrote the manuscript	planned, carried out the immobilization and fermentation experiments, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
5445041	28549373	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5445041	28549373	VM	2	participated in the plant analysis	participated in the plant analysis	Performed the experiments	Investigation	YES
5778441	29403505	All authors	2	have read and approved the manuscript	have read and approved the manuscript	-	-	NO
5494471	28483816	AB	2	also performed experiments	also performed experiments	Performed the experiments	Investigation	YES
5494471	28483816	AF	2	conceived and designed experiments	conceived and designed experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5494471	28483816	AL	2	carried out all purifications, pull-down and co-expression experiments|conceived and designed experiments	carried out all purifications, pull-down and co-expression experiments	Performed the experiments	Investigation	YES
5494471	28483816	AL	2	carried out all purifications, pull-down and co-expression experiments|conceived and designed experiments	conceived and designed experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5494471	28483816	All authors	2	analysed data|contributed to and corrected the manuscript	analysed data	Analyzed the data	Formal analysis	YES
5494471	28483816	All authors	2	analysed data|contributed to and corrected the manuscript	contributed to and corrected the manuscript	Wrote the paper	Writing - Review & Editing	YES
5494471	28483816	BG	2	conceived and designed experiments	conceived and designed experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5494471	28483816	J-BL	2	also performed experiments	also performed experiments	Performed the experiments	Investigation	YES
5494471	28483816	LT	2	conceived and designed experiments	conceived and designed experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5494471	28483816	LW	2	also performed experiments	also performed experiments	Performed the experiments	Investigation	YES
5494471	28483816	PRCI	2	performed the majority of the experiments|conceived and designed experiments	performed the majority of the experiments	Performed the experiments	Investigation	YES
5494471	28483816	PRCI	2	performed the majority of the experiments|conceived and designed experiments	conceived and designed experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5494471	28483816	PW	2	conceived and designed experiments	conceived and designed experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5494471	28483816	SB	2	also performed experiments|conceived and designed experiments	also performed experiments	Performed the experiments	Investigation	YES
5494471	28483816	SB	2	also performed experiments|conceived and designed experiments	conceived and designed experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5494471	28483816	SG	2	also performed experiments|also performed experiments	also performed experiments	Performed the experiments	Investigation	YES
5494471	28483816	SG	2	also performed experiments|also performed experiments	also performed experiments	Performed the experiments	Investigation	YES
5494471	28483816	SPS	2	also performed experiments|conceived and designed experiments|wrote the manuscript	also performed experiments	Performed the experiments	Investigation	YES
5494471	28483816	SPS	2	also performed experiments|conceived and designed experiments|wrote the manuscript	conceived and designed experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5494471	28483816	SPS	2	also performed experiments|conceived and designed experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5494471	28483816	TEW	2	also performed experiments	also performed experiments	Performed the experiments	Investigation	YES
5494471	28483816	TG	2	also performed experiments	also performed experiments	Performed the experiments	Investigation	YES
1949050	17726529	AC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1949050	17726529	AC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1949050	17726529	AC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1949050	17726529	AC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1949050	17726529	FT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1949050	17726529	FT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1949050	17726529	FT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1949050	17726529	FT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1949050	17726529	HK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1949050	17726529	HK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1949050	17726529	HK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1949050	17726529	MP	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1949050	17726529	MP	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1949050	17726529	MP	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1949050	17726529	ST	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1949050	17726529	ST	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5793405	29434529	AE	2	conducted most of the data collection	conducted most of the data collection	Performed the experiments	Investigation	YES
5793405	29434529	CE	2	conducted most of the data collection	conducted most of the data collection	Performed the experiments	Investigation	YES
5793405	29434529	CP	2	were involved in study design, data analysis and manuscript preparation	were involved in study design, data analysis and manuscript preparation	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5793405	29434529	JA	2	coordinated and supervised all data collection, data analysis and manuscript preparation	coordinated and supervised all data collection, data analysis and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Project administration|Supervision|Writing - Original Draft	YES
5793405	29434529	TS	2	were involved in study design, data analysis and manuscript preparation	were involved in study design, data analysis and manuscript preparation	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4416035	25927831	KJF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416035	25927831	KJF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416035	25927831	KJF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416035	25927831	KJF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416035	25927831	KJF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5702152	29178828	JQ	2	designed the work and drafted the article|also collected, processed the transcriptome data and performed bioinformatics analyses	designed the work and drafted the article	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
5702152	29178828	JQ	2	designed the work and drafted the article|also collected, processed the transcriptome data and performed bioinformatics analyses	also collected, processed the transcriptome data and performed bioinformatics analyses	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5702152	29178828	KHC	2	designed the work and drafted the article	designed the work and drafted the article	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
5702152	29178828	KYM	2	performed the evolutionary analysis	performed the evolutionary analysis	Performed the experiments	Investigation	YES
5702152	29178828	LMT	2	contributed to the data of 28 crab transcriptomes	contributed to the data of 28 crab transcriptomes	-	-	NO
5702152	29178828	LY	2	performed the evolutionary analysis	performed the evolutionary analysis	Performed the experiments	Investigation	YES
5702152	29178828	TF	2	motif inference	motif inference	-	-	NO
5702152	29178828	TFs	2	from genbank data	from genbank data	-	-	NO
5702152	29178828	XJ	2	contributed to the database and website construction	contributed to the database and website construction	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5702152	29178828	YH	2	contributed to the database and website construction	contributed to the database and website construction	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
4628730	26557692	Alice Fattori	2	contributed equally to this work|prepared the first draft of the paper, contributed to the interpretation of the results, and approved the final version of the paper	contributed equally to this work	-	-	NO
4628730	26557692	Alice Fattori	2	contributed equally to this work|prepared the first draft of the paper, contributed to the interpretation of the results, and approved the final version of the paper	prepared the first draft of the paper, contributed to the interpretation of the results, and approved the final version of the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4628730	26557692	Donatella Camerino	2	contributed to the interpretation of the results and approved the final version of the paper	contributed to the interpretation of the results and approved the final version of the paper	Analyzed the data	Formal analysis	YES
4628730	26557692	Giovanni Costa	2	contributed to the interpretation of the results and approved the final version of the paper	contributed to the interpretation of the results and approved the final version of the paper	Analyzed the data	Formal analysis	YES
4628730	26557692	Luca Neri	2	contributed equally to this work	contributed equally to this work	-	-	NO
4628730	26557692	MOSAICO	2	studies, developed the study concept for this paper, performed data analysis, contributed to the interpretation of the results, approved the final version of the paper, and takes full responsibility for data integrity|studies, performed research fielding, contributed to the interpretation of the results, and approved the final version of the paper	studies, developed the study concept for this paper, performed data analysis, contributed to the interpretation of the results, approved the final version of the paper, and takes full responsibility for data integrity	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Data curation|Formal analysis|Resources|Writing - Original Draft	YES
4628730	26557692	MOSAICO	2	studies, developed the study concept for this paper, performed data analysis, contributed to the interpretation of the results, approved the final version of the paper, and takes full responsibility for data integrity|studies, performed research fielding, contributed to the interpretation of the results, and approved the final version of the paper	studies, performed research fielding, contributed to the interpretation of the results, and approved the final version of the paper	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5445060	28549372	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5445060	28549372	QH	2	conceived the study, supervised the study, and wrote the paper	conceived the study, supervised the study, and wrote the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Supervision|Writing - Original Draft	YES
5445060	28549372	QS	2	conceived the study, supervised the study, and wrote the paper	conceived the study, supervised the study, and wrote the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Supervision|Writing - Original Draft	YES
5445060	28549372	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
4528420	26194757	A.M.W.	2	designed and performed the research, wrote the paper and approved the final version	designed and performed the research, wrote the paper and approved the final version	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
4528420	26194757	C.G.C.	2	designed and performed the research, wrote the paper and approved the final version	designed and performed the research, wrote the paper and approved the final version	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
4528420	26194757	Q.M.	2	designed and performed the research, wrote the paper and approved the final version	designed and performed the research, wrote the paper and approved the final version	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
4528420	26194757	T.M.	2	designed and performed the research, wrote the paper and approved the final version	designed and performed the research, wrote the paper and approved the final version	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
4528420	26194757	Y.E.	2	designed and performed the research, wrote the paper and approved the final version	designed and performed the research, wrote the paper and approved the final version	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
4528420	26194757	Z.S.	2	designed and performed the research, wrote the paper and approved the final version	designed and performed the research, wrote the paper and approved the final version	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5509998	28588064	HI	2	designed the endometriosis experiment and gave many useful comments	designed the endometriosis experiment and gave many useful comments	Conceived and designed the experiments	Methodology	YES
5509998	28588064	JA	2	supervised all aspects of the study, including experimental design, discussion, data interpretation, and modified the manuscript	supervised all aspects of the study, including experimental design, discussion, data interpretation, and modified the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Supervision|Writing - Review & Editing	YES
5509998	28588064	KK	2	designed the study and carried out most of the experiments	designed the study and carried out most of the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5509998	28588064	KO	2	mice and gave many useful comments	mice and gave many useful comments	-	-	NO
5509998	28588064	MA	2	designed and performed mediator lipidomics experiment	designed and performed mediator lipidomics experiment	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5509998	28588064	MK	2	designed the endometriosis experiment and gave many useful comments	designed the endometriosis experiment and gave many useful comments	Conceived and designed the experiments	Methodology	YES
5509998	28588064	MM	2	designed and carried out the experiment on dna microarray	designed and carried out the experiment on dna microarray	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5509998	28588064	SA	2	designed the study and carried out most of the experiments|wrote the draft of the manuscript	designed the study and carried out most of the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5509998	28588064	SA	2	designed the study and carried out most of the experiments|wrote the draft of the manuscript	wrote the draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
5509998	28588064	ST	2	designed and carried out the experiment on dna microarray	designed and carried out the experiment on dna microarray	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5509998	28588064	TF	2	designed the endometriosis experiment and gave many useful comments	designed the endometriosis experiment and gave many useful comments	Conceived and designed the experiments	Methodology	YES
5509998	28588064	TN	2	designed the endometriosis experiment and gave many useful comments	designed the endometriosis experiment and gave many useful comments	Conceived and designed the experiments	Methodology	YES
5509998	28588064	YH	2	designed the experiments on decidual reactions	designed the experiments on decidual reactions	Conceived and designed the experiments	Methodology	YES
5509998	28588064	YS	2	designed and carried out the experiment on dna microarray	designed and carried out the experiment on dna microarray	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5509998	28588064	YT	2	designed and carried out the experiment on dna microarray	designed and carried out the experiment on dna microarray	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5509998	28588064	YY	2	designed the endometriosis experiment and gave many useful comments	designed the endometriosis experiment and gave many useful comments	Conceived and designed the experiments	Methodology	YES
5778503	29403510	BioM	PLoS52	for proofreading this manuscript	for proofreading this manuscript	-	-	NO
5778503	29403510	CL	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5778503	29403510	DG	PLoS52	uploaded the database	uploaded the database	Contributed reagents/materials/analysis tools	Software	YES
5778503	29403510	KN	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5778503	29403510	KN	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5778503	29403510	LLC	PLoS52	for proofreading this manuscript	for proofreading this manuscript	-	-	NO
5778503	29403510	QW	PLoS52	conceived and designed the experiments|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5778503	29403510	QW	PLoS52	conceived and designed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5778503	29403510	RL	PLoS52	uploaded the database	uploaded the database	Contributed reagents/materials/analysis tools	Software	YES
5778503	29403510	SY	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5778503	29403510	WZ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5778503	29403510	Wang Labs	PLoS52	for discussions and help with techniques	for discussions and help with techniques	-	-	NO
5778503	29403510	XJ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5778503	29403510	XZ	PLoS52	conceived and designed the experiments|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5778503	29403510	XZ	PLoS52	conceived and designed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5778503	29403510	YD	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5778503	29403510	YD	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5778503	29403510	YH	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5778503	29403510	YH	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5778503	29403510	ZC	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5778503	29403510	ZC	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5778503	29403510	ZC	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5778503	29403510	ZC	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416036	25927238	AL	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416036	25927238	DC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416036	25927238	DC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416036	25927238	DC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416036	25927238	HK	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416036	25927238	HK	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416036	25927238	HK	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416036	25927238	HMM	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4416036	25927238	HMM	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416036	25927238	JH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416036	25927238	JH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416036	25927238	JH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5812048	29449791	All authors	2	contributed to the interpretation of the data writing of the manuscript	contributed to the interpretation of the data writing of the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
5812048	29449791	BK	2	made substantial contributions to the conception and design of the current study	made substantial contributions to the conception and design of the current study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5812048	29449791	BN	2	made substantial contributions to the conception and design of the current study|ran statistics on acquired data	made substantial contributions to the conception and design of the current study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5812048	29449791	BN	2	made substantial contributions to the conception and design of the current study|ran statistics on acquired data	ran statistics on acquired data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5812048	29449791	CM	2	contributed to the upkeep and financial acquisition for data acquisition	contributed to the upkeep and financial acquisition for data acquisition	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5812048	29449791	CW	2	made substantial contributions to the conception and design of the current study|ran statistics on acquired data	made substantial contributions to the conception and design of the current study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5812048	29449791	CW	2	made substantial contributions to the conception and design of the current study|ran statistics on acquired data	ran statistics on acquired data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5780347	29403519	CY	7	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5780347	29403519	HW	7	performed data analysis and wrote manuscript	performed data analysis and wrote manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5780347	29403519	LL	7	participated in experiment setup and measurements	participated in experiment setup and measurements	Performed the experiments	Investigation	YES
5780347	29403519	MW	7	participated in experiment measurements	participated in experiment measurements	Performed the experiments	Investigation	YES
5780347	29403519	TL	7	participated in experiment setup and measurements	participated in experiment setup and measurements	Performed the experiments	Investigation	YES
5780347	29403519	YL	7	participated in the data analysis	participated in the data analysis	Analyzed the data	Formal analysis	YES
5780347	29403519	ZQ	7	participated in editing of the manuscript	participated in editing of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5780347	29403519	ZW	7	designed the experiments, performed data analysis, and wrote manuscript	designed the experiments, performed data analysis, and wrote manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5702190	29178834	AF	PLoS52	conceived and designed the experiments|collected the samples|conducted analyses|critically revised the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5702190	29178834	AF	PLoS52	conceived and designed the experiments|collected the samples|conducted analyses|critically revised the manuscript	collected the samples	Performed the experiments	Investigation	YES
5702190	29178834	AF	PLoS52	conceived and designed the experiments|collected the samples|conducted analyses|critically revised the manuscript	conducted analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5702190	29178834	AF	PLoS52	conceived and designed the experiments|collected the samples|conducted analyses|critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5702190	29178834	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5702190	29178834	FCB	PLoS52	conceived and designed the experiments|critically revised the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5702190	29178834	FCB	PLoS52	conceived and designed the experiments|critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5702190	29178834	NVH	PLoS52	conceived and designed the experiments|collected the samples|conducted analyses|critically revised the manuscript|contributed equally to the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5702190	29178834	NVH	PLoS52	conceived and designed the experiments|collected the samples|conducted analyses|critically revised the manuscript|contributed equally to the manuscript	collected the samples	Performed the experiments	Investigation	YES
5702190	29178834	NVH	PLoS52	conceived and designed the experiments|collected the samples|conducted analyses|critically revised the manuscript|contributed equally to the manuscript	conducted analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5702190	29178834	NVH	PLoS52	conceived and designed the experiments|collected the samples|conducted analyses|critically revised the manuscript|contributed equally to the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5702190	29178834	NVH	PLoS52	conceived and designed the experiments|collected the samples|conducted analyses|critically revised the manuscript|contributed equally to the manuscript	contributed equally to the manuscript	-	-	NO
5702190	29178834	PPT	PLoS52	conducted analyses|prepared the first draft|contributed equally to the manuscript	conducted analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5702190	29178834	PPT	PLoS52	conducted analyses|prepared the first draft|contributed equally to the manuscript	prepared the first draft	Wrote the paper	Writing - Original Draft	YES
5702190	29178834	PPT	PLoS52	conducted analyses|prepared the first draft|contributed equally to the manuscript	contributed equally to the manuscript	-	-	NO
5702190	29178834	RJH	PLoS52	conceived and designed the experiments|critically revised the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5702190	29178834	RJH	PLoS52	conceived and designed the experiments|critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
1949102	17726530	JM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1949102	17726530	JM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1949102	17726530	JM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1949102	17726530	SB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1949102	17726530	SB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1949102	17726530	SB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1949102	17726530	SB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4528421	26194758	C.M.	2	designed and carried out the computational analysis, developed the statistical methods and wrote the paper	designed and carried out the computational analysis, developed the statistical methods and wrote the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4528421	26194758	F.M.	2	designed the computational analysis, developed the statistical methods and wrote the paper	designed the computational analysis, developed the statistical methods and wrote the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4528421	26194758	H.R.	2	helped define questions and provided the data	helped define questions and provided the data	Contributed reagents/materials/analysis tools	Resources	YES
4528421	26194758	P.B.	2	performed structural analysis	performed structural analysis	Performed the experiments	Investigation	YES
4528421	26194758	T.B.	2	designed the computational analysis, developed the statistical methods and wrote the paper	designed the computational analysis, developed the statistical methods and wrote the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4528421	26194758	V.M.	2	designed the computational analysis, developed the statistical methods and wrote the paper	designed the computational analysis, developed the statistical methods and wrote the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4416037	25927228	B. Brand	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416037	25927228	B. Brand	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416037	25927228	B. Brandt	PLoS5	Conceived and designed the experiments|Performed the experiments|Critical review and comments on data analyses and manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416037	25927228	B. Brandt	PLoS5	Conceived and designed the experiments|Performed the experiments|Critical review and comments on data analyses and manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4416037	25927228	B. Brandt	PLoS5	Conceived and designed the experiments|Performed the experiments|Critical review and comments on data analyses and manuscript	Critical review and comments on data analyses and manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4416037	25927228	DR	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Critical review and comments on data analyses and manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4416037	25927228	DR	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Critical review and comments on data analyses and manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416037	25927228	DR	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Critical review and comments on data analyses and manuscript	Critical review and comments on data analyses and manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4416037	25927228	FH	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Critical review and comments on data analyses and manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4416037	25927228	FH	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Critical review and comments on data analyses and manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416037	25927228	FH	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Critical review and comments on data analyses and manuscript	Critical review and comments on data analyses and manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4416037	25927228	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416037	25927228	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416037	25927228	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416037	25927228	KLG	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416037	25927228	KLG	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416037	25927228	MS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416037	25927228	MS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416037	25927228	NS	PLoS5	Contributed reagents/materials/analysis tools|Critical review and comments on data analyses and manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416037	25927228	NS	PLoS5	Contributed reagents/materials/analysis tools|Critical review and comments on data analyses and manuscript	Critical review and comments on data analyses and manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4416037	25927228	SP	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416037	25927228	SP	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5812230	29449792	DM	2	undertook data interpretation and manuscript preparation	undertook data interpretation and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5812230	29449792	IB	2	undertook data interpretation and manuscript preparation	undertook data interpretation and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5812230	29449792	M-CR	2	undertook data interpretation and manuscript preparation	undertook data interpretation and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5812230	29449792	MM	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5510000	28607004	AHES	2	synthesised the crosslinked substrates	synthesised the crosslinked substrates	-	-	NO
5510000	28607004	DP	2	purified the recombinant xpf-ercc1 protein	purified the recombinant xpf-ercc1 protein	Performed the experiments	Investigation	YES
5510000	28607004	JFM	2	synthesised the crosslinked substrates|purified the recombinant xpf-ercc1 protein|drafted and revised the manuscript, and all authors reviewed the manuscript and provided comments	synthesised the crosslinked substrates	-	-	NO
5510000	28607004	JFM	2	synthesised the crosslinked substrates|purified the recombinant xpf-ercc1 protein|drafted and revised the manuscript, and all authors reviewed the manuscript and provided comments	purified the recombinant xpf-ercc1 protein	Performed the experiments	Investigation	YES
5510000	28607004	JFM	2	synthesised the crosslinked substrates|purified the recombinant xpf-ercc1 protein|drafted and revised the manuscript, and all authors reviewed the manuscript and provided comments	drafted and revised the manuscript, and all authors reviewed the manuscript and provided comments	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5510000	28607004	PJM	2	designed the experiments|helped with the performed the experiments and analysed the data with|drafted and revised the manuscript, and all authors reviewed the manuscript and provided comments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5510000	28607004	PJM	2	designed the experiments|helped with the performed the experiments and analysed the data with|drafted and revised the manuscript, and all authors reviewed the manuscript and provided comments	helped with the performed the experiments and analysed the data with	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5510000	28607004	PJM	2	designed the experiments|helped with the performed the experiments and analysed the data with|drafted and revised the manuscript, and all authors reviewed the manuscript and provided comments	drafted and revised the manuscript, and all authors reviewed the manuscript and provided comments	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5510000	28607004	SB	2	helped with the performed the experiments and analysed the data with	helped with the performed the experiments and analysed the data with	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5510000	28607004	TB	2	synthesised the crosslinked substrates	synthesised the crosslinked substrates	-	-	NO
5510000	28607004	UBA	2	designed the experiments|performed the experiments and analysed the data with|purified the recombinant xpf-ercc1 protein|drafted and revised the manuscript, and all authors reviewed the manuscript and provided comments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5510000	28607004	UBA	2	designed the experiments|performed the experiments and analysed the data with|purified the recombinant xpf-ercc1 protein|drafted and revised the manuscript, and all authors reviewed the manuscript and provided comments	performed the experiments and analysed the data with	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5510000	28607004	UBA	2	designed the experiments|performed the experiments and analysed the data with|purified the recombinant xpf-ercc1 protein|drafted and revised the manuscript, and all authors reviewed the manuscript and provided comments	purified the recombinant xpf-ercc1 protein	Performed the experiments	Investigation	YES
5510000	28607004	UBA	2	designed the experiments|performed the experiments and analysed the data with|purified the recombinant xpf-ercc1 protein|drafted and revised the manuscript, and all authors reviewed the manuscript and provided comments	drafted and revised the manuscript, and all authors reviewed the manuscript and provided comments	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5449350	28565883	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5449350	28565883	HBH	2	designed and performed most of the experiments	designed and performed most of the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5449350	28565883	HC	2	conceived the study|designed and performed most of the experiments	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5449350	28565883	HC	2	conceived the study|designed and performed most of the experiments	designed and performed most of the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5449350	28565883	HW	2	edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5449350	28565883	JJZ	2	conceived the study|designed and performed most of the experiments|wrote the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5449350	28565883	JJZ	2	conceived the study|designed and performed most of the experiments|wrote the manuscript	designed and performed most of the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5449350	28565883	JJZ	2	conceived the study|designed and performed most of the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5449350	28565883	MJC	2	edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5449350	28565883	ZYF	2	conceived the study|edited the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5449350	28565883	ZYF	2	conceived the study|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
1949142	17726520	AS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1949142	17726520	FB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1949142	17726520	FB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1949142	17726520	FB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1949142	17726520	FB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1949142	17726520	JP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1949142	17726520	JP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1949142	17726520	JP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1949142	17726520	KJ	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1949142	17726520	KS	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1949142	17726520	KS	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1949142	17726520	MM	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1949142	17726520	MM	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1949142	17726520	SN	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5780430	29403507	AR	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5780430	29403507	AvA	PLoS52	analyzed the data|designed the research|wrote the article	analyzed the data	Analyzed the data	Formal analysis	YES
5780430	29403507	AvA	PLoS52	analyzed the data|designed the research|wrote the article	designed the research	Conceived and designed the experiments	Methodology	YES
5780430	29403507	AvA	PLoS52	analyzed the data|designed the research|wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
5780430	29403507	JT	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5780430	29403507	OC	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5780430	29403507	PA	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5780430	29403507	PA	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5780430	29403507	RE	PLoS52	performed the experiments|analyzed the data|designed the research|wrote the article	performed the experiments	Performed the experiments	Investigation	YES
5780430	29403507	RE	PLoS52	performed the experiments|analyzed the data|designed the research|wrote the article	analyzed the data	Analyzed the data	Formal analysis	YES
5780430	29403507	RE	PLoS52	performed the experiments|analyzed the data|designed the research|wrote the article	designed the research	Conceived and designed the experiments	Methodology	YES
5780430	29403507	RE	PLoS52	performed the experiments|analyzed the data|designed the research|wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
5780430	29403507	RH	PLoS52	designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
5780430	29403507	RU-C	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5780430	29403507	SC	PLoS52	performed the experiments|analyzed the data|designed the research	performed the experiments	Performed the experiments	Investigation	YES
5780430	29403507	SC	PLoS52	performed the experiments|analyzed the data|designed the research	analyzed the data	Analyzed the data	Formal analysis	YES
5780430	29403507	SC	PLoS52	performed the experiments|analyzed the data|designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
4528422	26194759	E.B.	2	wrote the software|wrote the manuscript	wrote the software	Contributed reagents/materials/analysis tools|Wrote the paper	Software|Writing - Original Draft	YES
4528422	26194759	E.B.	2	wrote the software|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4528422	26194759	L.C.	2	developed the model|wrote the manuscript	developed the model	Performed the experiments	Methodology	YES
4528422	26194759	L.C.	2	developed the model|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4528422	26194759	S.C.	2	developed the model|wrote the manuscript	developed the model	Performed the experiments	Methodology	YES
4528422	26194759	S.C.	2	developed the model|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5819236	29467598	AJ	4	The present study was designed by|data interpretation and manuscript preparation were undertaken by	The present study was designed by	Conceived and designed the experiments	Methodology	YES
5819236	29467598	AJ	4	The present study was designed by|data interpretation and manuscript preparation were undertaken by	data interpretation and manuscript preparation were undertaken by	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5819236	29467598	ASS	4	The present study was designed by|data interpretation and manuscript preparation were undertaken by	The present study was designed by	Conceived and designed the experiments	Methodology	YES
5819236	29467598	ASS	4	The present study was designed by|data interpretation and manuscript preparation were undertaken by	data interpretation and manuscript preparation were undertaken by	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5819236	29467598	BM	4	data interpretation and manuscript preparation were undertaken by	data interpretation and manuscript preparation were undertaken by	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5819236	29467598	EP	4	data interpretation and manuscript preparation were undertaken by	data interpretation and manuscript preparation were undertaken by	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5819236	29467598	JT	4	data were collected by	data were collected by	Performed the experiments	Investigation	YES
5819236	29467598	KL	4	data were collected by	data were collected by	Performed the experiments	Investigation	YES
5819236	29467598	PB	4	data were collected by	data were collected by	Performed the experiments	Investigation	YES
4416038	25928636	CC	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4416038	25928636	CC	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4416038	25928636	CC	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416038	25928636	FTK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416038	25928636	FTK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416038	25928636	FTK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416038	25928636	FTK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416038	25928636	HPV	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416038	25928636	HPV	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416038	25928636	HPV	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416038	25928636	HPV	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416038	25928636	ZAK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416038	25928636	ZAK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416038	25928636	ZAK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416038	25928636	ZAK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416038	25928636	ZAK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5702194	29178826	A-A	2	obtained the s|performed the transcriptome studies and obtained the extracts for metabolomic studies	obtained the s	-	-	NO
5702194	29178826	A-A	2	obtained the s|performed the transcriptome studies and obtained the extracts for metabolomic studies	performed the transcriptome studies and obtained the extracts for metabolomic studies	Performed the experiments	Investigation	YES
5702194	29178826	PL	2	directed the experiments, organized the data and write the manuscript	directed the experiments, organized the data and write the manuscript	Wrote the paper	Supervision|Writing - Original Draft	YES
5702194	29178826	R-G	2	analyzed the transcriptome data	analyzed the transcriptome data	Analyzed the data	Formal analysis	YES
5510004	28292785	DKD	2	designed the experiments|performed the majority of the experiments|discussed the data with the help of the other authors	designed the experiments	Conceived and designed the experiments	Methodology	YES
5510004	28292785	DKD	2	designed the experiments|performed the majority of the experiments|discussed the data with the help of the other authors	performed the majority of the experiments	Performed the experiments	Investigation	YES
5510004	28292785	DKD	2	designed the experiments|performed the majority of the experiments|discussed the data with the help of the other authors	discussed the data with the help of the other authors	-	-	NO
5510004	28292785	PK	2	designed the experiments|discussed the data with the help of the other authors	designed the experiments	Conceived and designed the experiments	Methodology	YES
5510004	28292785	PK	2	designed the experiments|discussed the data with the help of the other authors	discussed the data with the help of the other authors	-	-	NO
5510004	28292785	RACMB	2	performed some of the chip assays|commented on the manuscript	performed some of the chip assays	Performed the experiments	Investigation	YES
5510004	28292785	RACMB	2	performed some of the chip assays|commented on the manuscript	commented on the manuscript	-	-	NO
5510004	28292785	WSH	2	performed ip assays from extract and insect cells|commented on the manuscript	performed ip assays from extract and insect cells	Performed the experiments	Investigation	YES
5510004	28292785	WSH	2	performed ip assays from extract and insect cells|commented on the manuscript	commented on the manuscript	-	-	NO
5451374	28571306	All authors	PLoS52	edited the drafts of the manuscript|read and approved the final manuscript	edited the drafts of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5451374	28571306	All authors	PLoS52	edited the drafts of the manuscript|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5451374	28571306	JAV	PLoS52	supervised the experiments for solvent extraction of biosurfactants and sample preparation for uplc-ms analysis	supervised the experiments for solvent extraction of biosurfactants and sample preparation for uplc-ms analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Supervision	YES
5451374	28571306	MR	PLoS52	conceived and designed the experiments|analysed the esi-ms and uplc-ms data|contributed reagents/materials/analysis tools|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5451374	28571306	MR	PLoS52	conceived and designed the experiments|analysed the esi-ms and uplc-ms data|contributed reagents/materials/analysis tools|wrote the paper	analysed the esi-ms and uplc-ms data	Analyzed the data	Formal analysis	YES
5451374	28571306	MR	PLoS52	conceived and designed the experiments|analysed the esi-ms and uplc-ms data|contributed reagents/materials/analysis tools|wrote the paper	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5451374	28571306	MR	PLoS52	conceived and designed the experiments|analysed the esi-ms and uplc-ms data|contributed reagents/materials/analysis tools|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5451374	28571306	SK	PLoS52	contributed reagents/materials/analysis tools	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5451374	28571306	TN	PLoS52	conceived and designed the experiments|performed the experiments and analysed the antimicrobial activity data|analysed the esi-ms and uplc-ms data|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5451374	28571306	TN	PLoS52	conceived and designed the experiments|performed the experiments and analysed the antimicrobial activity data|analysed the esi-ms and uplc-ms data|wrote the paper	performed the experiments and analysed the antimicrobial activity data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5451374	28571306	TN	PLoS52	conceived and designed the experiments|performed the experiments and analysed the antimicrobial activity data|analysed the esi-ms and uplc-ms data|wrote the paper	analysed the esi-ms and uplc-ms data	Analyzed the data	Formal analysis	YES
5451374	28571306	TN	PLoS52	conceived and designed the experiments|performed the experiments and analysed the antimicrobial activity data|analysed the esi-ms and uplc-ms data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5451374	28571306	WK	PLoS52	conceived and designed the experiments|acquired funding for the study|contributed reagents/materials/analysis tools|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5451374	28571306	WK	PLoS52	conceived and designed the experiments|acquired funding for the study|contributed reagents/materials/analysis tools|wrote the paper	acquired funding for the study	-	Funding acquisition	YES
5451374	28571306	WK	PLoS52	conceived and designed the experiments|acquired funding for the study|contributed reagents/materials/analysis tools|wrote the paper	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5451374	28571306	WK	PLoS52	conceived and designed the experiments|acquired funding for the study|contributed reagents/materials/analysis tools|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4528486	26150654	All authors	2	contributed equally to the writing and revision of the manuscript	contributed equally to the writing and revision of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5828430	29497353	Both authors	2	equally contributed to the writing of the manuscript	equally contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5828430	29497353	Brad Schoenfeld	2	conceived of the article	conceived of the article	Conceived and designed the experiments	Conceptualization	YES
5538765	28572448	BK	2	designed all other assays|performed statistical analyses of assays	designed all other assays	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5538765	28572448	BK	2	designed all other assays|performed statistical analyses of assays	performed statistical analyses of assays	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5538765	28572448	PAH	2	designed all other assays|wrote a first draft of the manuscript to which all other authors contributed	designed all other assays	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5538765	28572448	PAH	2	designed all other assays|wrote a first draft of the manuscript to which all other authors contributed	wrote a first draft of the manuscript to which all other authors contributed	Wrote the paper	Writing - Original Draft	YES
5538765	28572448	PW	2	designed all other assays|performed notch-binding assays	designed all other assays	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5538765	28572448	PW	2	designed all other assays|performed notch-binding assays	performed notch-binding assays	Performed the experiments	Investigation	YES
5538765	28572448	RJS	2	collected x-ray data, solved and analysed atomic structures|wrote a first draft of the manuscript to which all other authors contributed	collected x-ray data, solved and analysed atomic structures	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5538765	28572448	RJS	2	collected x-ray data, solved and analysed atomic structures|wrote a first draft of the manuscript to which all other authors contributed	wrote a first draft of the manuscript to which all other authors contributed	Wrote the paper	Writing - Original Draft	YES
5538765	28572448	SML	2	collected x-ray data, solved and analysed atomic structures|performed statistical analyses of assays|wrote a first draft of the manuscript to which all other authors contributed	collected x-ray data, solved and analysed atomic structures	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5538765	28572448	SML	2	collected x-ray data, solved and analysed atomic structures|performed statistical analyses of assays|wrote a first draft of the manuscript to which all other authors contributed	performed statistical analyses of assays	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5538765	28572448	SML	2	collected x-ray data, solved and analysed atomic structures|performed statistical analyses of assays|wrote a first draft of the manuscript to which all other authors contributed	wrote a first draft of the manuscript to which all other authors contributed	Wrote the paper	Writing - Original Draft	YES
5780448	29403513	APC	2	but did not have any additional role in the study design, data collection and analysis, decision to publish, or preparation of the manuscript	but did not have any additional role in the study design, data collection and analysis, decision to publish, or preparation of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5780448	29403513	Both authors	2	have read the manuscript and agreed with its content	have read the manuscript and agreed with its content	-	-	NO
5780448	29403513	L. This	2	does not alter our adherence to all the frontiers in plant science policies on sharing data and materials	does not alter our adherence to all the frontiers in plant science policies on sharing data and materials	Performed the experiments	Investigation	YES
5780448	29403513	S.L.	2	but did not have any additional role in the study design, data collection and analysis, decision to publish, or preparation of the manuscript	but did not have any additional role in the study design, data collection and analysis, decision to publish, or preparation of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5780448	29403513	The other author	2	declares that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	declares that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	Performed the experiments	Investigation	YES
4416039	25927237	AKG	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416039	25927237	AKG	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416039	25927237	AKG	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416039	25927237	AKG	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416039	25927237	BS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416039	25927237	BS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416039	25927237	DM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416039	25927237	DM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416039	25927237	DM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416039	25927237	DM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416039	25927237	DM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1949143	17726519	SL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1949143	17726519	SL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1949143	17726519	SL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1949143	17726519	SL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1949143	17726519	SL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5702197	29178836	GJK	2	collected and analyzed data and wrote manuscript|authors have approved the final version to be published	collected and analyzed data and wrote manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5702197	29178836	GJK	2	collected and analyzed data and wrote manuscript|authors have approved the final version to be published	authors have approved the final version to be published	-	-	NO
5702197	29178836	JRN	2	provided guidance with experimental design, data analysis and critical revision of the article|authors have approved the final version to be published	provided guidance with experimental design, data analysis and critical revision of the article	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Supervision|Writing - Review & Editing	YES
5702197	29178836	JRN	2	provided guidance with experimental design, data analysis and critical revision of the article|authors have approved the final version to be published	authors have approved the final version to be published	-	-	NO
5451376	28571307	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5451376	28571307	MR	PLoS52	contributed to the experimental design|analysed the esi-ms and uplc-ms data|contributed reagents/materials/analysis tools|wrote the paper	contributed to the experimental design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5451376	28571307	MR	PLoS52	contributed to the experimental design|analysed the esi-ms and uplc-ms data|contributed reagents/materials/analysis tools|wrote the paper	analysed the esi-ms and uplc-ms data	Analyzed the data	Formal analysis	YES
5451376	28571307	MR	PLoS52	contributed to the experimental design|analysed the esi-ms and uplc-ms data|contributed reagents/materials/analysis tools|wrote the paper	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5451376	28571307	MR	PLoS52	contributed to the experimental design|analysed the esi-ms and uplc-ms data|contributed reagents/materials/analysis tools|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5451376	28571307	SK	PLoS52	contributed reagents/materials/analysis tools	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5451376	28571307	TN	PLoS52	performed the experiments|analysed the esi-ms and uplc-ms data|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5451376	28571307	TN	PLoS52	performed the experiments|analysed the esi-ms and uplc-ms data|wrote the paper	analysed the esi-ms and uplc-ms data	Analyzed the data	Formal analysis	YES
5451376	28571307	TN	PLoS52	performed the experiments|analysed the esi-ms and uplc-ms data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5451376	28571307	WK	PLoS52	acquired funding for the study|contributed reagents/materials/analysis tools|wrote the paper	acquired funding for the study	-	Funding acquisition	YES
5451376	28571307	WK	PLoS52	acquired funding for the study|contributed reagents/materials/analysis tools|wrote the paper	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5451376	28571307	WK	PLoS52	acquired funding for the study|contributed reagents/materials/analysis tools|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5839013	29527137	BL	2	conducted the study selection, data extraction, and methodological quality assessment|contributed to writing the manuscript	conducted the study selection, data extraction, and methodological quality assessment	Performed the experiments|Analyzed the data	Data curation|Investigation|Methodology|Validation	YES
5839013	29527137	BL	2	conducted the study selection, data extraction, and methodological quality assessment|contributed to writing the manuscript	contributed to writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5839013	29527137	ET	2	contributed to writing the manuscript	contributed to writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5839013	29527137	JG	2	conceived the idea and conceptualized the review|conducted the study selection, data extraction, and methodological quality assessment|conducted the meta-analysis|drafted the initial manuscript|contributed to writing the manuscript	conceived the idea and conceptualized the review	Conceived and designed the experiments	Conceptualization	YES
5839013	29527137	JG	2	conceived the idea and conceptualized the review|conducted the study selection, data extraction, and methodological quality assessment|conducted the meta-analysis|drafted the initial manuscript|contributed to writing the manuscript	conducted the study selection, data extraction, and methodological quality assessment	Performed the experiments|Analyzed the data	Data curation|Investigation|Methodology|Validation	YES
5839013	29527137	JG	2	conceived the idea and conceptualized the review|conducted the study selection, data extraction, and methodological quality assessment|conducted the meta-analysis|drafted the initial manuscript|contributed to writing the manuscript	conducted the meta-analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5839013	29527137	JG	2	conceived the idea and conceptualized the review|conducted the study selection, data extraction, and methodological quality assessment|conducted the meta-analysis|drafted the initial manuscript|contributed to writing the manuscript	drafted the initial manuscript	Wrote the paper	Writing - Original Draft	YES
5839013	29527137	JG	2	conceived the idea and conceptualized the review|conducted the study selection, data extraction, and methodological quality assessment|conducted the meta-analysis|drafted the initial manuscript|contributed to writing the manuscript	contributed to writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5839013	29527137	ZP	2	conceived the idea and conceptualized the review|contributed to writing the manuscript	conceived the idea and conceptualized the review	Conceived and designed the experiments	Conceptualization	YES
5839013	29527137	ZP	2	conceived the idea and conceptualized the review|contributed to writing the manuscript	contributed to writing the manuscript	Wrote the paper	Writing - Original Draft	YES
4528487	26150655	A.J.Y.	2	conceived the study and wrote the manuscript	conceived the study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4528487	26150655	U.D.K.	2	performed coding, simulations and analyses and contributed to the manuscript	performed coding, simulations and analyses and contributed to the manuscript	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5538795	28607003	EV	2	designed and performed experiments	designed and performed experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5538795	28607003	HG	2	designed and performed experiments	designed and performed experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5538795	28607003	NPa	2	designed and performed experiments	designed and performed experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5538795	28607003	NPi	2	designed and performed experiments	designed and performed experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5538795	28607003	RY	2	designed and performed experiments|analyzed the experiments and wrote the manuscript	designed and performed experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5538795	28607003	RY	2	designed and performed experiments|analyzed the experiments and wrote the manuscript	analyzed the experiments and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5538795	28607003	SB-D	2	analyzed the microarray data	analyzed the microarray data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5538795	28607003	SM	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5538795	28607003	VK	2	analyzed the experiments and wrote the manuscript|supervised the project	analyzed the experiments and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5538795	28607003	VK	2	analyzed the experiments and wrote the manuscript|supervised the project	supervised the project	-	Supervision	YES
5538795	28607003	YO	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5538795	28607003	ZP	2	analyzed imagestream experiments	analyzed imagestream experiments	Analyzed the data	Formal analysis|Visualization	YES
1949144	17726521	AP	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1949144	17726521	CM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1949144	17726521	CW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1949144	17726521	CW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1949144	17726521	CW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1949144	17726521	CW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1949144	17726521	CW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1949144	17726521	MH	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1949144	17726521	NN	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1949144	17726521	NN	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1949144	17726521	NN	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1949144	17726521	PK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1949144	17726521	PK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1949144	17726521	PK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1949144	17726521	PK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1949144	17726521	RC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1949144	17726521	SP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1949144	17726521	SW	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1949144	17726521	SW	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1949144	17726521	SW	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416040	25927363	CT	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416040	25927363	CT	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416040	25927363	CT	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416040	25927363	DH	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416040	25927363	DH	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416040	25927363	PC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416040	25927363	PC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416040	25927363	PC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416040	25927363	VT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416040	25927363	VT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416040	25927363	VT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416040	25927363	VT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5780453	29403521	AD	7	conceived the idea and led the study design; BZ, SA	conceived the idea and led the study design; BZ, SA	Conceived and designed the experiments	Conceptualization|Methodology	YES
5780453	29403521	AQ	7	assisted with study design and experiments	assisted with study design and experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5780453	29403521	BZ	7	conceived the idea and led the study design; BZ, SA	conceived the idea and led the study design; BZ, SA	Conceived and designed the experiments	Conceptualization|Methodology	YES
5780453	29403521	DN	7	edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5780453	29403521	JX	7	assisted with study design and experiments	assisted with study design and experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5780453	29403521	JZ	7	assisted with study design and experiments	assisted with study design and experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5780453	29403521	QY	7	edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5780453	29403521	U-K	7	carried out the experiment, performed analysis and wrote the paper	carried out the experiment, performed analysis and wrote the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5780453	29403521	YZ	7	edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5780453	29403521	ZhL	7	carried out the experiment, performed analysis and wrote the paper	carried out the experiment, performed analysis and wrote the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5780453	29403521	ZuL	7	assisted with study design and experiments	assisted with study design and experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5845356	29556158	AP	2	conception and design of research|edited and revised manuscript|approved final version of manuscript	conception and design of research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5845356	29556158	AP	2	conception and design of research|edited and revised manuscript|approved final version of manuscript	edited and revised manuscript	Wrote the paper	Writing - Review & Editing	YES
5845356	29556158	AP	2	conception and design of research|edited and revised manuscript|approved final version of manuscript	approved final version of manuscript	-	-	NO
5845356	29556158	AS	2	conception and design of research|analysed data|edited and revised manuscript|approved final version of manuscript	conception and design of research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5845356	29556158	AS	2	conception and design of research|analysed data|edited and revised manuscript|approved final version of manuscript	analysed data	Analyzed the data	Formal analysis	YES
5845356	29556158	AS	2	conception and design of research|analysed data|edited and revised manuscript|approved final version of manuscript	edited and revised manuscript	Wrote the paper	Writing - Review & Editing	YES
5845356	29556158	AS	2	conception and design of research|analysed data|edited and revised manuscript|approved final version of manuscript	approved final version of manuscript	-	-	NO
5845356	29556158	FD	2	conception and design of research|analysed data|edited and revised manuscript|approved final version of manuscript	conception and design of research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5845356	29556158	FD	2	conception and design of research|analysed data|edited and revised manuscript|approved final version of manuscript	analysed data	Analyzed the data	Formal analysis	YES
5845356	29556158	FD	2	conception and design of research|analysed data|edited and revised manuscript|approved final version of manuscript	edited and revised manuscript	Wrote the paper	Writing - Review & Editing	YES
5845356	29556158	FD	2	conception and design of research|analysed data|edited and revised manuscript|approved final version of manuscript	approved final version of manuscript	-	-	NO
5845356	29556158	JAT	2	conception and design of research|edited and revised manuscript|approved final version of manuscript	conception and design of research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5845356	29556158	JAT	2	conception and design of research|edited and revised manuscript|approved final version of manuscript	edited and revised manuscript	Wrote the paper	Writing - Review & Editing	YES
5845356	29556158	JAT	2	conception and design of research|edited and revised manuscript|approved final version of manuscript	approved final version of manuscript	-	-	NO
5845356	29556158	JR	2	conception and design of research|performed experiments|analysed data|drafted manuscript|edited and revised manuscript|approved final version of manuscript	conception and design of research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5845356	29556158	JR	2	conception and design of research|performed experiments|analysed data|drafted manuscript|edited and revised manuscript|approved final version of manuscript	performed experiments	Performed the experiments	Investigation	YES
5845356	29556158	JR	2	conception and design of research|performed experiments|analysed data|drafted manuscript|edited and revised manuscript|approved final version of manuscript	analysed data	Analyzed the data	Formal analysis	YES
5845356	29556158	JR	2	conception and design of research|performed experiments|analysed data|drafted manuscript|edited and revised manuscript|approved final version of manuscript	drafted manuscript	Wrote the paper	Writing - Original Draft	YES
5845356	29556158	JR	2	conception and design of research|performed experiments|analysed data|drafted manuscript|edited and revised manuscript|approved final version of manuscript	edited and revised manuscript	Wrote the paper	Writing - Review & Editing	YES
5845356	29556158	JR	2	conception and design of research|performed experiments|analysed data|drafted manuscript|edited and revised manuscript|approved final version of manuscript	approved final version of manuscript	-	-	NO
5845356	29556158	MM	2	conception and design of research|performed experiments|analysed data|interpreted results of experiments|drafted manuscript|edited and revised manuscript|approved final version of manuscript	conception and design of research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5845356	29556158	MM	2	conception and design of research|performed experiments|analysed data|interpreted results of experiments|drafted manuscript|edited and revised manuscript|approved final version of manuscript	performed experiments	Performed the experiments	Investigation	YES
5845356	29556158	MM	2	conception and design of research|performed experiments|analysed data|interpreted results of experiments|drafted manuscript|edited and revised manuscript|approved final version of manuscript	analysed data	Analyzed the data	Formal analysis	YES
5845356	29556158	MM	2	conception and design of research|performed experiments|analysed data|interpreted results of experiments|drafted manuscript|edited and revised manuscript|approved final version of manuscript	interpreted results of experiments	Analyzed the data	Formal analysis	YES
5845356	29556158	MM	2	conception and design of research|performed experiments|analysed data|interpreted results of experiments|drafted manuscript|edited and revised manuscript|approved final version of manuscript	drafted manuscript	Wrote the paper	Writing - Original Draft	YES
5845356	29556158	MM	2	conception and design of research|performed experiments|analysed data|interpreted results of experiments|drafted manuscript|edited and revised manuscript|approved final version of manuscript	edited and revised manuscript	Wrote the paper	Writing - Review & Editing	YES
5845356	29556158	MM	2	conception and design of research|performed experiments|analysed data|interpreted results of experiments|drafted manuscript|edited and revised manuscript|approved final version of manuscript	approved final version of manuscript	-	-	NO
5845356	29556158	VP	2	conception and design of research|performed experiments|analysed data|interpreted results of experiments|drafted manuscript	conception and design of research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5845356	29556158	VP	2	conception and design of research|performed experiments|analysed data|interpreted results of experiments|drafted manuscript	performed experiments	Performed the experiments	Investigation	YES
5845356	29556158	VP	2	conception and design of research|performed experiments|analysed data|interpreted results of experiments|drafted manuscript	analysed data	Analyzed the data	Formal analysis	YES
5845356	29556158	VP	2	conception and design of research|performed experiments|analysed data|interpreted results of experiments|drafted manuscript	interpreted results of experiments	Analyzed the data	Formal analysis	YES
5845356	29556158	VP	2	conception and design of research|performed experiments|analysed data|interpreted results of experiments|drafted manuscript	drafted manuscript	Wrote the paper	Writing - Original Draft	YES
5845356	29556158	XC	2	conception and design of research|performed experiments|analysed data|approved final version of manuscript	conception and design of research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5845356	29556158	XC	2	conception and design of research|performed experiments|analysed data|approved final version of manuscript	performed experiments	Performed the experiments	Investigation	YES
5845356	29556158	XC	2	conception and design of research|performed experiments|analysed data|approved final version of manuscript	analysed data	Analyzed the data	Formal analysis	YES
5845356	29556158	XC	2	conception and design of research|performed experiments|analysed data|approved final version of manuscript	approved final version of manuscript	-	-	NO
5702214	29178827	CG	PLoS52	designed research|contributed new reagents/analytic tools|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
5702214	29178827	CG	PLoS52	designed research|contributed new reagents/analytic tools|wrote the paper	contributed new reagents/analytic tools	Contributed reagents/materials/analysis tools	Resources	YES
5702214	29178827	CG	PLoS52	designed research|contributed new reagents/analytic tools|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5702214	29178827	DY	PLoS52	designed research|performed research	designed research	Conceived and designed the experiments	Methodology	YES
5702214	29178827	DY	PLoS52	designed research|performed research	performed research	Performed the experiments	Investigation	YES
5702214	29178827	JE	PLoS52	designed research|analyzed data|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
5702214	29178827	JE	PLoS52	designed research|analyzed data|wrote the paper	analyzed data	Analyzed the data	Formal analysis	YES
5702214	29178827	JE	PLoS52	designed research|analyzed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5702214	29178827	VG	PLoS52	designed research|performed research|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
5702214	29178827	VG	PLoS52	designed research|performed research|wrote the paper	performed research	Performed the experiments	Investigation	YES
5702214	29178827	VG	PLoS52	designed research|performed research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5702214	29178827	XM	PLoS52	contributed new reagents/analytic tools	contributed new reagents/analytic tools	Contributed reagents/materials/analysis tools	Resources	YES
5457369	28582970	AE	2	implemented the conception and design of article besides the acquisition of the data	implemented the conception and design of article besides the acquisition of the data	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5457369	28582970	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5457369	28582970	GS	2	endorsed the final approval of article and funded the work	endorsed the final approval of article and funded the work	-	Funding acquisition	YES
5457369	28582970	LZ	2	carried out the critical revision of article for important intellectual content	carried out the critical revision of article for important intellectual content	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5457369	28582970	SL	2	analyzed and interpreted of the data	analyzed and interpreted of the data	Analyzed the data	Formal analysis	YES
5457369	28582970	YL	2	presented the administrative, technical, and logistic support	presented the administrative, technical, and logistic support	Performed the experiments	Investigation|Project administration	YES
4528488	26150656	J.L.	2	conducted the study	conducted the study	Performed the experiments	Investigation	YES
4528488	26150656	O.G.P.	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
4528488	26150656	P.K.	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
4528488	26150656	P.S.W.	2	conducted the study	conducted the study	Performed the experiments	Investigation	YES
4528488	26150656	S.G.	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
4528488	26150656	all authors	2	were involved in analysis and interpretation of model results and available data and in writing the paper	were involved in analysis and interpretation of model results and available data and in writing the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
1949145	17726531	MM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1949145	17726531	MM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1949145	17726531	MM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1949145	17726531	MM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1949145	17726531	PO	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1949145	17726531	PR	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1949145	17726531	PR	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1949145	17726531	RT	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1949145	17726531	RW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1949145	17726531	RW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1949145	17726531	RW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1949145	17726531	RW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1949145	17726531	VR	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416041	25927597	DR	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4416041	25927597	DR	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416041	25927597	IE	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416041	25927597	KM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4416041	25927597	KM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416041	25927597	MR	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416041	25927597	RPW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416041	25927597	RPW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416041	25927597	RPW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416041	25927597	RPW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416041	25927597	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416041	25927597	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416041	25927597	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416041	25927597	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416041	25927597	SS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4416041	25927597	SS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5556270	28716804	AMD	2	carried out the experimental work	carried out the experimental work	Performed the experiments	Investigation	YES
5556270	28716804	ANRC	2	helped design the project and carried out the microscopy work	helped design the project and carried out the microscopy work	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5556270	28716804	ASM	2	conceived and designed the project and supervised the research|wrote the manuscript, with valuable input from all the other authors	conceived and designed the project and supervised the research	Conceived and designed the experiments	Conceptualization|Methodology|Supervision	YES
5556270	28716804	ASM	2	conceived and designed the project and supervised the research|wrote the manuscript, with valuable input from all the other authors	wrote the manuscript, with valuable input from all the other authors	Wrote the paper	Writing - Original Draft	YES
5556270	28716804	ATP-A	2	carried out the experimental work|contributed to the design of in vitro and in vivo assays	carried out the experimental work	Performed the experiments	Investigation	YES
5556270	28716804	ATP-A	2	carried out the experimental work|contributed to the design of in vitro and in vivo assays	contributed to the design of in vitro and in vivo assays	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5556270	28716804	BGD	2	supervised some of the research	supervised some of the research	-	Supervision	YES
5556270	28716804	CJ	2	provided ifna6gfp mice	provided ifna6gfp mice	Contributed reagents/materials/analysis tools	Resources	YES
5556270	28716804	DMD	2	provided some equipment and supervised some of the research	provided some equipment and supervised some of the research	Contributed reagents/materials/analysis tools	Resources|Supervision	YES
5556270	28716804	FR	2	supervised some of the research	supervised some of the research	-	Supervision	YES
5556270	28716804	JGB	2	helped design the project and carried out the microscopy work	helped design the project and carried out the microscopy work	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5556270	28716804	LHJ-J	2	carried out the experimental work|contributed to the design of in vitro and in vivo assays	carried out the experimental work	Performed the experiments	Investigation	YES
5556270	28716804	LHJ-J	2	carried out the experimental work|contributed to the design of in vitro and in vivo assays	contributed to the design of in vitro and in vivo assays	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5556270	28716804	LMC	2	carried out the experimental work	carried out the experimental work	Performed the experiments	Investigation	YES
5556270	28716804	LMW	2	designed the project and coordinated and carried out the experimental work|wrote the manuscript, with valuable input from all the other authors	designed the project and coordinated and carried out the experimental work	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Project administration	YES
5556270	28716804	LMW	2	designed the project and coordinated and carried out the experimental work|wrote the manuscript, with valuable input from all the other authors	wrote the manuscript, with valuable input from all the other authors	Wrote the paper	Writing - Original Draft	YES
5556270	28716804	PCC	2	carried out the experimental work|contributed to the design of in vitro and in vivo assays	carried out the experimental work	Performed the experiments	Investigation	YES
5556270	28716804	PCC	2	carried out the experimental work|contributed to the design of in vitro and in vivo assays	contributed to the design of in vitro and in vivo assays	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5556270	28716804	RHPW	2	contributed recombinant omega-1	contributed recombinant omega-1	Performed the experiments	Investigation	YES
5556270	28716804	RJL	2	designed the project and coordinated and carried out the experimental work|wrote the manuscript, with valuable input from all the other authors	designed the project and coordinated and carried out the experimental work	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Project administration	YES
5556270	28716804	RJL	2	designed the project and coordinated and carried out the experimental work|wrote the manuscript, with valuable input from all the other authors	wrote the manuscript, with valuable input from all the other authors	Wrote the paper	Writing - Original Draft	YES
5556270	28716804	SLB	2	carried out the experimental work	carried out the experimental work	Performed the experiments	Investigation	YES
4528489	26150657	B.A.	2	conceived and designed the study, and wrote and revised the article	conceived and designed the study, and wrote and revised the article	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
4528489	26150657	C.R.M.B.	2	conceived and designed the study, and wrote and revised the article	conceived and designed the study, and wrote and revised the article	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
4528489	26150657	D.J.L.	2	performed the literature review and analysed the data|conceived and designed the study, and wrote and revised the article	performed the literature review and analysed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4528489	26150657	D.J.L.	2	performed the literature review and analysed the data|conceived and designed the study, and wrote and revised the article	conceived and designed the study, and wrote and revised the article	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
1949146	17726514	BN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1949146	17726514	BN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1949146	17726514	BN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1949146	17726514	BN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1949146	17726514	BN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1949146	17726514	EV	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1949146	17726514	EV	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1949146	17726514	EV	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5780454	29403520	All authors	2	edited and approved the final manuscript	edited and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5780454	29403520	BW	2	designed and conducted experiments, analyzed data, and wrote the manuscript	designed and conducted experiments, analyzed data, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5780454	29403520	GG	2	provided soybean germplasm and analyzed data	provided soybean germplasm and analyzed data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5780454	29403520	KA	2	designed rna seq protocols and performed transcriptomic analysis	designed rna seq protocols and performed transcriptomic analysis	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5853147	29568243	All other authors	2	contributed to data collection and interpretation, and critically reviewed the manuscript	contributed to data collection and interpretation, and critically reviewed the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
5853147	29568243	KI	2	designed this research and wrote the initial draft of the manuscript	designed this research and wrote the initial draft of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5853147	29568243	KN	2	contributed to the analysis and interpretation of data, and assisted in the preparation of the manuscript	contributed to the analysis and interpretation of data, and assisted in the preparation of the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
5853147	29568243	KR	2	contributed to the analysis and interpretation of data, and assisted in the preparation of the manuscript	contributed to the analysis and interpretation of data, and assisted in the preparation of the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
5853147	29568243	TM	2	designed this research and wrote the initial draft of the manuscript|contributed to the analysis and interpretation of data, and assisted in the preparation of the manuscript	designed this research and wrote the initial draft of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5853147	29568243	TM	2	designed this research and wrote the initial draft of the manuscript|contributed to the analysis and interpretation of data, and assisted in the preparation of the manuscript	contributed to the analysis and interpretation of data, and assisted in the preparation of the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
5853147	29568243	YT	2	contributed to the analysis and interpretation of data, and assisted in the preparation of the manuscript	contributed to the analysis and interpretation of data, and assisted in the preparation of the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
5704545	29179676	HS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5704545	29179676	HS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
5704545	29179676	HS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
5704545	29179676	HS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5704545	29179676	HS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5704545	29179676	KK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5704545	29179676	KK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5704545	29179676	KK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5704545	29179676	YK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5704545	29179676	YK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
5704545	29179676	YK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5704545	29179676	YK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5704545	29179676	all authors	PLoS5	Read and approved the manuscript	Read and approved the manuscript	-	-	NO
5457376	28582973	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5457376	28582973	DK	2	helped in protein expression experiments	helped in protein expression experiments	Performed the experiments	Investigation	YES
5457376	28582973	EA	2	assisted in expression optimizations	assisted in expression optimizations	Performed the experiments	Investigation	YES
5457376	28582973	FR	2	precipitated in gene construct preparation and confirmation	precipitated in gene construct preparation and confirmation	Performed the experiments	Investigation	YES
5457376	28582973	MA	2	helped in protein expression experiments and purification steps	helped in protein expression experiments and purification steps	Performed the experiments	Investigation	YES
5457376	28582973	MZ	2	helped in mtt assays	helped in mtt assays	Performed the experiments	Investigation	YES
5457376	28582973	NZ	2	participated in flow cytometry analysis	participated in flow cytometry analysis	Performed the experiments	Investigation	YES
5457376	28582973	SAA	2	performed the experiments and wrote the first draft of the manuscript	performed the experiments and wrote the first draft of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5457376	28582973	SS	2	participated in experimental design	participated in experimental design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5457376	28582973	VK	2	designed and coordinated the study, supervised all experimental steps and revised and finalized the manuscript	designed and coordinated the study, supervised all experimental steps and revised and finalized the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Supervision|Writing - Review & Editing	YES
4628739	26557697	Claudia Sandoval-Montes	PLoS52	supervised the experiments|provided a critical review of the paper	supervised the experiments	-	Supervision	YES
4628739	26557697	Claudia Sandoval-Montes	PLoS52	supervised the experiments|provided a critical review of the paper	provided a critical review of the paper	Wrote the paper	Writing - Review & Editing	YES
4628739	26557697	Ezequiel M. Fuentes-Panana	PLoS52	designed the study and interpreted the results|supervised the experiments	designed the study and interpreted the results	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
4628739	26557697	Ezequiel M. Fuentes-Panana	PLoS52	designed the study and interpreted the results|supervised the experiments	supervised the experiments	-	Supervision	YES
4628739	26557697	Gabriela Vallejo-Flores	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
4628739	26557697	Haruki Arevalo-Romero	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
4628739	26557697	Isaura Meza	PLoS52	designed the study and interpreted the results|supervised the experiments|provided a critical review of the paper	designed the study and interpreted the results	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
4628739	26557697	Isaura Meza	PLoS52	designed the study and interpreted the results|supervised the experiments|provided a critical review of the paper	supervised the experiments	-	Supervision	YES
4628739	26557697	Isaura Meza	PLoS52	designed the study and interpreted the results|supervised the experiments|provided a critical review of the paper	provided a critical review of the paper	Wrote the paper	Writing - Review & Editing	YES
4628739	26557697	Javier Torres	PLoS52	designed the study and interpreted the results|supervised the experiments|provided a critical review of the paper	designed the study and interpreted the results	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
4628739	26557697	Javier Torres	PLoS52	designed the study and interpreted the results|supervised the experiments|provided a critical review of the paper	supervised the experiments	-	Supervision	YES
4628739	26557697	Javier Torres	PLoS52	designed the study and interpreted the results|supervised the experiments|provided a critical review of the paper	provided a critical review of the paper	Wrote the paper	Writing - Review & Editing	YES
4628739	26557697	Julian Torres-Morales	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
4628739	26557697	Victoria Legorreta-Haquet	PLoS52	helped with the proliferation assays and the flow cytometry	helped with the proliferation assays and the flow cytometry	Performed the experiments	Investigation	YES
4416042	25927927	HS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416042	25927927	HS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416042	25927927	HS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416042	25927927	HS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416042	25927927	K. Shimamoto	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416042	25927927	K. Shimamoto	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416042	25927927	MK	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5556271	28694244	A-TH	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
5556271	28694244	AR-F	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
5556271	28694244	AS	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
5556271	28694244	CN	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
5556271	28694244	DA	CRediT	Resources	Resources	Contributed reagents/materials/analysis tools	Resources	YES
5556271	28694244	DMB	CRediT	Methodology|Supervision	Methodology	Performed the experiments	Methodology	YES
5556271	28694244	DMB	CRediT	Methodology|Supervision	Supervision	-	Supervision	YES
5556271	28694244	EJM	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
5556271	28694244	EK	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
5556271	28694244	FP	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
5556271	28694244	JM	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
5556271	28694244	JRH-F	CRediT	Resources	Resources	Contributed reagents/materials/analysis tools	Resources	YES
5556271	28694244	JS	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
5556271	28694244	KB	CRediT	Methodology|Resources	Methodology	Performed the experiments	Methodology	YES
5556271	28694244	KB	CRediT	Methodology|Resources	Resources	Contributed reagents/materials/analysis tools	Resources	YES
5556271	28694244	KS	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
5556271	28694244	LJN	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
5556271	28694244	LMC	CRediT	Conceptualization|Methodology|Data curation|Supervision	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
5556271	28694244	LMC	CRediT	Conceptualization|Methodology|Data curation|Supervision	Methodology	Performed the experiments	Methodology	YES
5556271	28694244	LMC	CRediT	Conceptualization|Methodology|Data curation|Supervision	Data curation	Analyzed the data	Data curation	YES
5556271	28694244	LMC	CRediT	Conceptualization|Methodology|Data curation|Supervision	Supervision	-	Supervision	YES
5556271	28694244	LMM	CRediT	Supervision	Supervision	-	Supervision	YES
5556271	28694244	MM	CRediT	Conceptualization|Methodology|Data curation|Supervision	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
5556271	28694244	MM	CRediT	Conceptualization|Methodology|Data curation|Supervision	Methodology	Performed the experiments	Methodology	YES
5556271	28694244	MM	CRediT	Conceptualization|Methodology|Data curation|Supervision	Data curation	Analyzed the data	Data curation	YES
5556271	28694244	MM	CRediT	Conceptualization|Methodology|Data curation|Supervision	Supervision	-	Supervision	YES
5556271	28694244	MS-S	CRediT	Supervision	Supervision	-	Supervision	YES
5556271	28694244	RHA	CRediT	Resources	Resources	Contributed reagents/materials/analysis tools	Resources	YES
5556271	28694244	SD	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
5556271	28694244	SER	CRediT	Conceptualization|Methodology|Investigation|Data curation|Writing - original draft|Visualization	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
5556271	28694244	SER	CRediT	Conceptualization|Methodology|Investigation|Data curation|Writing - original draft|Visualization	Methodology	Performed the experiments	Methodology	YES
5556271	28694244	SER	CRediT	Conceptualization|Methodology|Investigation|Data curation|Writing - original draft|Visualization	Investigation	Performed the experiments	Investigation	YES
5556271	28694244	SER	CRediT	Conceptualization|Methodology|Investigation|Data curation|Writing - original draft|Visualization	Data curation	Analyzed the data	Data curation	YES
5556271	28694244	SER	CRediT	Conceptualization|Methodology|Investigation|Data curation|Writing - original draft|Visualization	Writing - original draft	Wrote the paper	Writing - Original Draft	YES
5556271	28694244	SER	CRediT	Conceptualization|Methodology|Investigation|Data curation|Writing - original draft|Visualization	Visualization	Analyzed the data	Visualization	YES
5556271	28694244	SI	CRediT	Supervision	Supervision	-	Supervision	YES
5556271	28694244	SZ	CRediT	Conceptualization|Methodology|Investigation|Data curation|Writing - original draft|Visualization|Supervision	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
5556271	28694244	SZ	CRediT	Conceptualization|Methodology|Investigation|Data curation|Writing - original draft|Visualization|Supervision	Methodology	Performed the experiments	Methodology	YES
5556271	28694244	SZ	CRediT	Conceptualization|Methodology|Investigation|Data curation|Writing - original draft|Visualization|Supervision	Investigation	Performed the experiments	Investigation	YES
5556271	28694244	SZ	CRediT	Conceptualization|Methodology|Investigation|Data curation|Writing - original draft|Visualization|Supervision	Data curation	Analyzed the data	Data curation	YES
5556271	28694244	SZ	CRediT	Conceptualization|Methodology|Investigation|Data curation|Writing - original draft|Visualization|Supervision	Writing - original draft	Wrote the paper	Writing - Original Draft	YES
5556271	28694244	SZ	CRediT	Conceptualization|Methodology|Investigation|Data curation|Writing - original draft|Visualization|Supervision	Visualization	Analyzed the data	Visualization	YES
5556271	28694244	SZ	CRediT	Conceptualization|Methodology|Investigation|Data curation|Writing - original draft|Visualization|Supervision	Supervision	-	Supervision	YES
5556271	28694244	VP	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
5556271	28694244	YE	CRediT	Resources	Resources	Contributed reagents/materials/analysis tools	Resources	YES
4528493	26150661	All authors	PLoS52	interpreted the data and wrote the article	interpreted the data and wrote the article	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4528493	26150661	G.B.	PLoS52	acquired the data	acquired the data	Performed the experiments	Investigation	YES
4528493	26150661	H.C.H.	PLoS52	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4528493	26150661	J.K.	PLoS52	analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
4528493	26150661	S.E.P.	PLoS52	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
1949147	17726525	AB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1949147	17726525	JB	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1949147	17726525	JC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1949147	17726525	JC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1949147	17726525	JC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1949147	17726525	KL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1949147	17726525	KL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1949147	17726525	KL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1949147	17726525	KL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1949147	17726525	KL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1949147	17726525	QS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1949147	17726525	SP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1949147	17726525	TK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1949147	17726525	TM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1949147	17726525	TM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1949147	17726525	TM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1949147	17726525	TM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5457379	28582972	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5457379	28582972	GL	2	helped in experiment operation and data analysis	helped in experiment operation and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5457379	28582972	MS	2	helped in experiment operation and data analysis	helped in experiment operation and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5457379	28582972	SZ	2	gave advices in the research work and revised the manuscript	gave advices in the research work and revised the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5457379	28582972	XG	2	gave advices in the research work and revised the manuscript	gave advices in the research work and revised the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5457379	28582972	YD	2	designed and conducted the experiments, analyzed the results and drafted the manuscript	designed and conducted the experiments, analyzed the results and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5457379	28582972	YR	2	helped in research design, data analysis and drafting manuscript	helped in research design, data analysis and drafting manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5457379	28582972	ZH	2	gave advices in the research work and revised the manuscript	gave advices in the research work and revised the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5457379	28582972	ZY	2	gave advices in the research work and revised the manuscript	gave advices in the research work and revised the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5780703	29403516	AB	2	extracted genomic dna and rna from watermelon fruit flesh	extracted genomic dna and rna from watermelon fruit flesh	Performed the experiments	Investigation	YES
5780703	29403516	AL	2	maintained the research materials and recorded the phenotypic data	maintained the research materials and recorded the phenotypic data	Performed the experiments	Investigation	YES
5780703	29403516	All authors	2	agree to account for the accuracy and integrity of the paper	agree to account for the accuracy and integrity of the paper	-	-	NO
5780703	29403516	BG	2	extracted genomic dna and rna from watermelon fruit flesh|wrote and approved the final version of the manuscript	extracted genomic dna and rna from watermelon fruit flesh	Performed the experiments	Investigation	YES
5780703	29403516	BG	2	extracted genomic dna and rna from watermelon fruit flesh|wrote and approved the final version of the manuscript	wrote and approved the final version of the manuscript	Wrote the paper	Writing - Original Draft	YES
5780703	29403516	CL	2	analyzed the data using the bioinformatic pipeline|wrote and approved the final version of the manuscript	analyzed the data using the bioinformatic pipeline	Analyzed the data	Formal analysis	YES
5780703	29403516	CL	2	analyzed the data using the bioinformatic pipeline|wrote and approved the final version of the manuscript	wrote and approved the final version of the manuscript	Wrote the paper	Writing - Original Draft	YES
5780703	29403516	MG	2	analyzed the data using the bioinformatic pipeline|wrote and approved the final version of the manuscript	analyzed the data using the bioinformatic pipeline	Analyzed the data	Formal analysis	YES
5780703	29403516	MG	2	analyzed the data using the bioinformatic pipeline|wrote and approved the final version of the manuscript	wrote and approved the final version of the manuscript	Wrote the paper	Writing - Original Draft	YES
5780703	29403516	NB	2	designed the plan of study|analyzed the data using the bioinformatic pipeline|wrote and approved the final version of the manuscript	designed the plan of study	Conceived and designed the experiments	Methodology	YES
5780703	29403516	NB	2	designed the plan of study|analyzed the data using the bioinformatic pipeline|wrote and approved the final version of the manuscript	analyzed the data using the bioinformatic pipeline	Analyzed the data	Formal analysis	YES
5780703	29403516	NB	2	designed the plan of study|analyzed the data using the bioinformatic pipeline|wrote and approved the final version of the manuscript	wrote and approved the final version of the manuscript	Wrote the paper	Writing - Original Draft	YES
5780703	29403516	PN	2	designed the plan of study|wrote and approved the final version of the manuscript	designed the plan of study	Conceived and designed the experiments	Methodology	YES
5780703	29403516	PN	2	designed the plan of study|wrote and approved the final version of the manuscript	wrote and approved the final version of the manuscript	Wrote the paper	Writing - Original Draft	YES
5780703	29403516	TS	2	designed the plan of study|extracted genomic dna and rna from watermelon fruit flesh|analyzed the data using the bioinformatic pipeline|wrote and approved the final version of the manuscript	designed the plan of study	Conceived and designed the experiments	Methodology	YES
5780703	29403516	TS	2	designed the plan of study|extracted genomic dna and rna from watermelon fruit flesh|analyzed the data using the bioinformatic pipeline|wrote and approved the final version of the manuscript	extracted genomic dna and rna from watermelon fruit flesh	Performed the experiments	Investigation	YES
5780703	29403516	TS	2	designed the plan of study|extracted genomic dna and rna from watermelon fruit flesh|analyzed the data using the bioinformatic pipeline|wrote and approved the final version of the manuscript	analyzed the data using the bioinformatic pipeline	Analyzed the data	Formal analysis	YES
5780703	29403516	TS	2	designed the plan of study|extracted genomic dna and rna from watermelon fruit flesh|analyzed the data using the bioinformatic pipeline|wrote and approved the final version of the manuscript	wrote and approved the final version of the manuscript	Wrote the paper	Writing - Original Draft	YES
5780703	29403516	UR	2	designed the plan of study|analyzed the data using the bioinformatic pipeline|wrote and approved the final version of the manuscript	designed the plan of study	Conceived and designed the experiments	Methodology	YES
5780703	29403516	UR	2	designed the plan of study|analyzed the data using the bioinformatic pipeline|wrote and approved the final version of the manuscript	analyzed the data using the bioinformatic pipeline	Analyzed the data	Formal analysis	YES
5780703	29403516	UR	2	designed the plan of study|analyzed the data using the bioinformatic pipeline|wrote and approved the final version of the manuscript	wrote and approved the final version of the manuscript	Wrote the paper	Writing - Original Draft	YES
5780703	29403516	VA	2	maintained the research materials and recorded the phenotypic data	maintained the research materials and recorded the phenotypic data	Performed the experiments	Investigation	YES
5856322	29568244	AP	2	revised manuscript	revised manuscript	Wrote the paper	Writing - Review & Editing	YES
5856322	29568244	GK	2	revised manuscript	revised manuscript	Wrote the paper	Writing - Review & Editing	YES
5856322	29568244	JP	2	revised manuscript	revised manuscript	Wrote the paper	Writing - Review & Editing	YES
5856322	29568244	LH	2	revised manuscript	revised manuscript	Wrote the paper	Writing - Review & Editing	YES
5856322	29568244	MM	2	revised manuscript	revised manuscript	Wrote the paper	Writing - Review & Editing	YES
5856322	29568244	MS	2	draft and revision of manuscript	draft and revision of manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5856322	29568244	OS	2	draft and revision of manuscript	draft and revision of manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5704640	29179677	All authors	2	contributed to the preparation of the manuscript	contributed to the preparation of the manuscript	Wrote the paper	Writing - Original Draft	YES
5704640	29179677	HC	2	interpreted data	interpreted data	Analyzed the data	Formal analysis	YES
5704640	29179677	HDY	2	designed data analyses	designed data analyses	Conceived and designed the experiments|Analyzed the data	Formal analysis	YES
5704640	29179677	HPL	2	conceived the project|performed computational experiments|designed data analyses|interpreted data|wrote the manuscript	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5704640	29179677	HPL	2	conceived the project|performed computational experiments|designed data analyses|interpreted data|wrote the manuscript	performed computational experiments	Performed the experiments	Formal analysis|Investigation	YES
5704640	29179677	HPL	2	conceived the project|performed computational experiments|designed data analyses|interpreted data|wrote the manuscript	designed data analyses	Conceived and designed the experiments|Analyzed the data	Formal analysis	YES
5704640	29179677	HPL	2	conceived the project|performed computational experiments|designed data analyses|interpreted data|wrote the manuscript	interpreted data	Analyzed the data	Formal analysis	YES
5704640	29179677	HPL	2	conceived the project|performed computational experiments|designed data analyses|interpreted data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5704640	29179677	JH	2	performed computational experiments	performed computational experiments	Performed the experiments	Formal analysis|Investigation	YES
5704640	29179677	KS	2	interpreted data	interpreted data	Analyzed the data	Formal analysis	YES
5704640	29179677	QZG	2	performed computational experiments	performed computational experiments	Performed the experiments	Formal analysis|Investigation	YES
5704640	29179677	RC	2	designed data analyses	designed data analyses	Conceived and designed the experiments|Analyzed the data	Formal analysis	YES
5704640	29179677	WCZ	2	designed data analyses	designed data analyses	Conceived and designed the experiments|Analyzed the data	Formal analysis	YES
5704640	29179677	XLW	2	conceived the project|wrote the manuscript	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5704640	29179677	XLW	2	conceived the project|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5704640	29179677	YG	2	interpreted data	interpreted data	Analyzed the data	Formal analysis	YES
5704640	29179677	YWL	2	performed computational experiments	performed computational experiments	Performed the experiments	Formal analysis|Investigation	YES
5704640	29179677	ZG	2	conceived the project|wrote the manuscript	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5704640	29179677	ZG	2	conceived the project|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4528494	26150662	C.C.	5	wrote the paper with assistance from A	wrote the paper with assistance from A	Wrote the paper	Writing - Original Draft	YES
4528494	26150662	P.G.	5	wrote the paper with assistance from A	wrote the paper with assistance from A	Wrote the paper	Writing - Original Draft	YES
5579346	28701485	CW	2	performed research|analyzed data|wrote the manuscript	performed research	Performed the experiments	Investigation	YES
5579346	28701485	CW	2	performed research|analyzed data|wrote the manuscript	analyzed data	Analyzed the data	Formal analysis	YES
5579346	28701485	CW	2	performed research|analyzed data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5579346	28701485	KUF	2	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5579346	28701485	RD	2	performed research	performed research	Performed the experiments	Investigation	YES
5579346	28701485	TNS	2	designed research|analyzed data|wrote the manuscript	designed research	Conceived and designed the experiments	Methodology	YES
5579346	28701485	TNS	2	designed research|analyzed data|wrote the manuscript	analyzed data	Analyzed the data	Formal analysis	YES
5579346	28701485	TNS	2	designed research|analyzed data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4416043	25928135	AQ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416043	25928135	AQ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416043	25928135	AQ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416043	25928135	HY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416043	25928135	HY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416043	25928135	HY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416043	25928135	HY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416043	25928135	KD	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416043	25928135	MHZ	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416043	25928135	MHZ	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416043	25928135	NJP	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416043	25928135	NJP	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416043	25928135	SR	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416043	25928135	TSC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416043	25928135	TSC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416043	25928135	TSC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1949148	17726515	CP	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Performed calculations and analysis|Helped develop ideas	Performed the experiments	Performed the experiments	Investigation	YES
1949148	17726515	CP	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Performed calculations and analysis|Helped develop ideas	Analyzed the data	Analyzed the data	Formal analysis	YES
1949148	17726515	CP	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Performed calculations and analysis|Helped develop ideas	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1949148	17726515	CP	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Performed calculations and analysis|Helped develop ideas	Performed calculations and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
1949148	17726515	CP	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Performed calculations and analysis|Helped develop ideas	Helped develop ideas	Conceived and designed the experiments	Conceptualization	YES
1949148	17726515	MG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Contributed to development of ideas|Gathered and analyzed empirical data|Assisted in editing	Analyzed the data	Analyzed the data	Formal analysis	YES
1949148	17726515	MG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Contributed to development of ideas|Gathered and analyzed empirical data|Assisted in editing	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1949148	17726515	MG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Contributed to development of ideas|Gathered and analyzed empirical data|Assisted in editing	Contributed to development of ideas	Conceived and designed the experiments	Conceptualization	YES
1949148	17726515	MG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Contributed to development of ideas|Gathered and analyzed empirical data|Assisted in editing	Gathered and analyzed empirical data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
1949148	17726515	MG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Contributed to development of ideas|Gathered and analyzed empirical data|Assisted in editing	Assisted in editing	Wrote the paper	Writing - Review & Editing	YES
1949148	17726515	ST	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1949148	17726515	ST	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1949148	17726515	ST	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1949148	17726515	ST	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416044	25927438	LZ	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4416044	25927438	LZ	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416044	25927438	MG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4416044	25927438	MG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416044	25927438	MZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416044	25927438	MZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416044	25927438	MZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416044	25927438	MZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416044	25927438	MZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416044	25927438	ST	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416044	25927438	ST	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416044	25927438	ST	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5457385	28582971	All	2	datasets on which the conclusions of this manuscript are based upon are available from the corresponding author upon request	datasets on which the conclusions of this manuscript are based upon are available from the corresponding author upon request	-	-	NO
5457385	28582971	BMP	2	contributed to experimental design and edited the manuscript	contributed to experimental design and edited the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
5457385	28582971	Both authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5457385	28582971	LWJ	2	contributed to experimental design, carried out all experiments and data analysis, and drafted and revised the manuscript	contributed to experimental design, carried out all experiments and data analysis, and drafted and revised the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5457385	28582971	Peter Cotty	2	for equipment use and technical advice, and to the reviewers and editors for helpful suggestions regarding the presentation of this work	for equipment use and technical advice, and to the reviewers and editors for helpful suggestions regarding the presentation of this work	Performed the experiments	Investigation	YES
5457385	28582971	The Fund	2	had no role in the design, collection, analysis, interpretation, or writing of the manuscript	had no role in the design, collection, analysis, interpretation, or writing of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5457385	28582971	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5457385	28582971	USDA-ARS	2	for equipment use and technical advice, and to the reviewers and editors for helpful suggestions regarding the presentation of this work	for equipment use and technical advice, and to the reviewers and editors for helpful suggestions regarding the presentation of this work	Performed the experiments	Investigation	YES
4528495	26150663	B.K.	2	designed the study, analysed the data and wrote the manuscript	designed the study, analysed the data and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4528495	26150663	N.P.	2	conducted all laboratory work and aided in preparation of the manuscript	conducted all laboratory work and aided in preparation of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5706307	29183281	BP	PLoS5	Conceived and designed the experiments|Performed metagenomic analysis|Statistical analysis	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5706307	29183281	BP	PLoS5	Conceived and designed the experiments|Performed metagenomic analysis|Statistical analysis	Performed metagenomic analysis	Performed the experiments	Investigation	YES
5706307	29183281	BP	PLoS5	Conceived and designed the experiments|Performed metagenomic analysis|Statistical analysis	Statistical analysis	Analyzed the data	Formal analysis	YES
5706307	29183281	DP	PLoS5	Performed metagenomic analysis	Performed metagenomic analysis	Performed the experiments	Investigation	YES
5706307	29183281	DTB	PLoS5	Performed metagenomic analysis	Performed metagenomic analysis	Performed the experiments	Investigation	YES
5706307	29183281	ED	PLoS5	Conceived and designed the experiments|Critical revision of the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5706307	29183281	ED	PLoS5	Conceived and designed the experiments|Critical revision of the manuscript	Critical revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5706307	29183281	FT	PLoS5	Data collection and sequencing experiments	Data collection and sequencing experiments	Performed the experiments	Investigation	YES
5706307	29183281	GGS	PLoS5	Performed metagenomic analysis	Performed metagenomic analysis	Performed the experiments	Investigation	YES
5706307	29183281	JMH	PLoS5	Data collection and sequencing experiments	Data collection and sequencing experiments	Performed the experiments	Investigation	YES
5706307	29183281	KW	PLoS5	Data collection and sequencing experiments	Data collection and sequencing experiments	Performed the experiments	Investigation	YES
5706307	29183281	MD	PLoS5	Data collection and sequencing experiments	Data collection and sequencing experiments	Performed the experiments	Investigation	YES
5706307	29183281	MM	PLoS5	Data collection and sequencing experiments	Data collection and sequencing experiments	Performed the experiments	Investigation	YES
5706307	29183281	PZ	PLoS5	Statistical analysis	Statistical analysis	Analyzed the data	Formal analysis	YES
5706307	29183281	RE	PLoS5	Critical revision of the manuscript	Critical revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4628742	26557679	Da Ren	2	contributed equally to this work	contributed equally to this work	-	-	NO
4628742	26557679	Dong Fang	2	contributed equally to this work	contributed equally to this work	-	-	NO
5786533	29403522	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5885383	29632452	APC	2	collected all data presented in this analysis|edited the manuscript	collected all data presented in this analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5885383	29632452	APC	2	collected all data presented in this analysis|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5885383	29632452	HLM	2	collected all data presented in this analysis|edited the manuscript	collected all data presented in this analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5885383	29632452	HLM	2	collected all data presented in this analysis|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5885383	29632452	LMM	2	collected all data presented in this analysis|analyzed and interpreted data results|prepared tables, figures, and drafted manuscript	collected all data presented in this analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5885383	29632452	LMM	2	collected all data presented in this analysis|analyzed and interpreted data results|prepared tables, figures, and drafted manuscript	analyzed and interpreted data results	Analyzed the data	Formal analysis	YES
5885383	29632452	LMM	2	collected all data presented in this analysis|analyzed and interpreted data results|prepared tables, figures, and drafted manuscript	prepared tables, figures, and drafted manuscript	Wrote the paper	Visualization|Writing - Original Draft	YES
5885383	29632452	NDB	2	prepared tables, figures, and drafted manuscript	prepared tables, figures, and drafted manuscript	Wrote the paper	Visualization|Writing - Original Draft	YES
5885383	29632452	SMP	2	collected all data presented in this analysis|edited the manuscript	collected all data presented in this analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5885383	29632452	SMP	2	collected all data presented in this analysis|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
1949492	17726526	GR	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1949492	17726526	KL	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1949492	17726526	MH	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1949492	17726526	MN	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1949492	17726526	MN	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1949492	17726526	SB	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1949492	17726526	SJ	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416045	25927441	LJL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416045	25927441	LJL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416045	25927441	LJL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416045	25927441	LXP	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416045	25927441	WWP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416045	25927441	WWP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416045	25927441	WWP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416045	25927441	WWP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416045	25927441	YYF	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416045	25927441	ZBZ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416045	25927441	ZJB	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5608784	28478485	All authors	2	were involved in the implementation of the study and preparation of the manuscript	were involved in the implementation of the study and preparation of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5608784	28478485	Clinical Oncology	2	to review this data if requested	to review this data if requested	-	-	NO
5579359	28716805	AB	2	provided technical help and analysed data	provided technical help and analysed data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5579359	28716805	JM	2	conceived the study, designed experiments, analysed data and wrote the manuscript|performed all experiments	conceived the study, designed experiments, analysed data and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
5579359	28716805	JM	2	conceived the study, designed experiments, analysed data and wrote the manuscript|performed all experiments	performed all experiments	Performed the experiments	Investigation	YES
5579359	28716805	JR	2	conceived the study, designed experiments, analysed data and wrote the manuscript	conceived the study, designed experiments, analysed data and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
5579359	28716805	LL	2	provided technical help and analysed data	provided technical help and analysed data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5459775	28587441	JJLL	1	Experiment planning and design|Paper construction	Experiment planning and design	Conceived and designed the experiments	Methodology	YES
5459775	28587441	JJLL	1	Experiment planning and design|Paper construction	Paper construction	Performed the experiments	Investigation	YES
5459775	28587441	STC	1	Experiment planning and design|Paper construction	Experiment planning and design	Conceived and designed the experiments	Methodology	YES
5459775	28587441	STC	1	Experiment planning and design|Paper construction	Paper construction	Performed the experiments	Investigation	YES
5459775	28587441	WNC	1	Paper construction	Paper construction	Performed the experiments	Investigation	YES
4528496	26150664	L.M.c.N.	2	contributed to the development of the ideas presented in the paper, and wrote and revised the paper	contributed to the development of the ideas presented in the paper, and wrote and revised the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
4528496	26150664	S.P.B.	2	contributed to the development of the ideas presented in the paper, and wrote and revised the paper	contributed to the development of the ideas presented in the paper, and wrote and revised the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
1950075	17726516	CA	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1950075	17726516	CA	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1950075	17726516	CA	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1950075	17726516	FG	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1950075	17726516	FG	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1950075	17726516	IP	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1950075	17726516	IP	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1950075	17726516	IP	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5709839	29191164	AB	2	performed the comparative analyses|wrote the paper with the	performed the comparative analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5709839	29191164	AB	2	performed the comparative analyses|wrote the paper with the	wrote the paper with the	Wrote the paper	Writing - Original Draft	YES
5709839	29191164	MK	2	performed the comparative analyses|assisted with the wrote the paper with the	performed the comparative analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5709839	29191164	MK	2	performed the comparative analyses|assisted with the wrote the paper with the	assisted with the wrote the paper with the	Wrote the paper	Writing - Original Draft	YES
5709839	29191164	TJP	2	conceived the study|developed the weighted likelihood estimator|wrote the paper with the	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5709839	29191164	TJP	2	conceived the study|developed the weighted likelihood estimator|wrote the paper with the	developed the weighted likelihood estimator	Analyzed the data	Formal analysis	YES
5709839	29191164	TJP	2	conceived the study|developed the weighted likelihood estimator|wrote the paper with the	wrote the paper with the	Wrote the paper	Writing - Original Draft	YES
5709839	29191164	ZAS	2	developed the weighted likelihood estimator|performed the comparative analyses|assisted with the wrote the paper with the	developed the weighted likelihood estimator	Analyzed the data	Formal analysis	YES
5709839	29191164	ZAS	2	developed the weighted likelihood estimator|performed the comparative analyses|assisted with the wrote the paper with the	performed the comparative analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5709839	29191164	ZAS	2	developed the weighted likelihood estimator|performed the comparative analyses|assisted with the wrote the paper with the	assisted with the wrote the paper with the	Wrote the paper	Writing - Original Draft	YES
4416046	25927999	HR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416046	25927999	HR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416046	25927999	HR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416046	25927999	HR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416046	25927999	HR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416046	25927999	LM	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416046	25927999	LM	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416046	25927999	RA	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416046	25927999	RA	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416046	25927999	US	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4416046	25927999	US	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4628743	26557681	In-Sung Yeo	2	contributed equally to this work	contributed equally to this work	-	-	NO
4628743	26557681	Ki-Hong Lee	2	contributed equally to this work	contributed equally to this work	-	-	NO
5891908	29643758	AD	2	collected and analysed data, and approved the final version of the manuscript	collected and analysed data, and approved the final version of the manuscript	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5891908	29643758	DV	2	designed the study, analysed the data and drafted the manuscript	designed the study, analysed the data and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5891908	29643758	KS	2	collected and analysed data, and approved the final version of the manuscript	collected and analysed data, and approved the final version of the manuscript	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5891908	29643758	ZR	2	designed the study and approved the final version of the manuscript	designed the study and approved the final version of the manuscript	Conceived and designed the experiments	Methodology	YES
5891908	29643758	ZU	2	collected and analysed data, and approved the final version of the manuscript	collected and analysed data, and approved the final version of the manuscript	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5786550	29403517	FW	2	collected data and carried out all analyses	collected data and carried out all analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5786550	29403517	NS	2	wrote this manuscript|conceptualized the idea and revised the manuscript	wrote this manuscript	Wrote the paper	Writing - Original Draft	YES
5786550	29403517	NS	2	wrote this manuscript|conceptualized the idea and revised the manuscript	conceptualized the idea and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5786550	29403517	SL	2	wrote this manuscript|performed experiments|collected data and carried out all analyses	wrote this manuscript	Wrote the paper	Writing - Original Draft	YES
5786550	29403517	SL	2	wrote this manuscript|performed experiments|collected data and carried out all analyses	performed experiments	Performed the experiments	Investigation	YES
5786550	29403517	SL	2	wrote this manuscript|performed experiments|collected data and carried out all analyses	collected data and carried out all analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5786550	29403517	SW	2	conceptualized the idea and revised the manuscript	conceptualized the idea and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5786550	29403517	YW	2	performed experiments|collected data and carried out all analyses	performed experiments	Performed the experiments	Investigation	YES
5786550	29403517	YW	2	performed experiments|collected data and carried out all analyses	collected data and carried out all analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5786550	29403517	ZY	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5599795	28729434	JM	2	interpreted the data and wrote the manuscript	interpreted the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5599795	28729434	L-S	2	interpreted the data and wrote the manuscript	interpreted the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5599795	28729434	LL-S	2	designed research|interpreted the data and wrote the manuscript	designed research	Conceived and designed the experiments	Methodology	YES
5599795	28729434	LL-S	2	designed research|interpreted the data and wrote the manuscript	interpreted the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5599795	28729434	RK	2	designed research|interpreted the data and wrote the manuscript	designed research	Conceived and designed the experiments	Methodology	YES
5599795	28729434	RK	2	designed research|interpreted the data and wrote the manuscript	interpreted the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5599795	28729434	TMG	2	generated the smc2-aid mutant	generated the smc2-aid mutant	Performed the experiments	Investigation	YES
4416047	25928539	CHC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416047	25928539	CHC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416047	25928539	CHC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416047	25928539	CPC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416047	25928539	CPC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416047	25928539	CPC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416047	25928539	CPC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416047	25928539	CYC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416047	25928539	CYC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4416047	25928539	CYC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416047	25928539	HCW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416047	25928539	HCW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416047	25928539	HCW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416047	25928539	HCW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416047	25928539	HJK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416047	25928539	HJK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416047	25928539	HJK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416047	25928539	KLK	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416047	25928539	LCS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4416047	25928539	LCS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416047	25928539	SCC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416047	25928539	SCC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4416047	25928539	SCC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416047	25928539	SGS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4416047	25928539	SGS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1950076	17726537	AR	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1950076	17726537	AY	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1950076	17726537	ED	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1950076	17726537	ED	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1950076	17726537	MK	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1950076	17726537	OZ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1950076	17726537	RB	PLoS5	Performed the biological experiment|Conceived and designed the biological experiment	Performed the biological experiment	Performed the experiments	Investigation	YES
1950076	17726537	RB	PLoS5	Performed the biological experiment|Conceived and designed the biological experiment	Conceived and designed the biological experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
1950076	17726537	VR	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1950076	17726537	YB	PLoS5	Conceived and designed the biological experiment	Conceived and designed the biological experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
1950076	17726537	YT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1950076	17726537	YT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1950076	17726537	YT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1950076	17726537	YT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5459778	28587442	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5459778	28587442	CSC	2	designed and coordinated the study|highly contributed for the manuscript revision	designed and coordinated the study	Conceived and designed the experiments	Methodology|Project administration	YES
5459778	28587442	CSC	2	designed and coordinated the study|highly contributed for the manuscript revision	highly contributed for the manuscript revision	Wrote the paper	Writing - Review & Editing	YES
5459778	28587442	JCAF	2	carried out the experimental work|drafted the manuscript	carried out the experimental work	Performed the experiments	Investigation	YES
5459778	28587442	JCAF	2	carried out the experimental work|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5459778	28587442	JM	2	designed and coordinated the study|carried out the experimental work|drafted the manuscript	designed and coordinated the study	Conceived and designed the experiments	Methodology|Project administration	YES
5459778	28587442	JM	2	designed and coordinated the study|carried out the experimental work|drafted the manuscript	carried out the experimental work	Performed the experiments	Investigation	YES
5459778	28587442	JM	2	designed and coordinated the study|carried out the experimental work|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5459778	28587442	RMW	2	highly contributed for the manuscript revision	highly contributed for the manuscript revision	Wrote the paper	Writing - Review & Editing	YES
5907737	29713248	AF	2	assisted with decision making regarding modifications to the questionnaire, participant recruitment, and manuscript preparation	assisted with decision making regarding modifications to the questionnaire, participant recruitment, and manuscript preparation	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5907737	29713248	GLT	2	undertook all data analysis, wrote the majority of the manuscript and oversaw participant recruitment and the manuscript preparation	undertook all data analysis, wrote the majority of the manuscript and oversaw participant recruitment and the manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Supervision|Writing - Original Draft	YES
5907737	29713248	RB	2	assisted with decision making regarding modifications to the questionnaire, participant recruitment, and manuscript preparation	assisted with decision making regarding modifications to the questionnaire, participant recruitment, and manuscript preparation	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5907737	29713248	RH	2	assisted with participant recruitment and manuscript preparation	assisted with participant recruitment and manuscript preparation	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5786554	29403524	AA	2	performed the auxin quali- quantification	performed the auxin quali- quantification	Performed the experiments	Investigation	YES
5786554	29403524	AS	2	performed the auxin quali- quantification	performed the auxin quali- quantification	Performed the experiments	Investigation	YES
5786554	29403524	CB	2	performed the auxin quali- quantification|revised the text based on feedback from all the coauthors	performed the auxin quali- quantification	Performed the experiments	Investigation	YES
5786554	29403524	CB	2	performed the auxin quali- quantification|revised the text based on feedback from all the coauthors	revised the text based on feedback from all the coauthors	Wrote the paper	Writing - Review & Editing	YES
5786554	29403524	EB	2	contributed to carry out the experiments on bacterial growth assays	contributed to carry out the experiments on bacterial growth assays	Performed the experiments	Investigation	YES
5786554	29403524	FG	2	executed the metabolite extraction and hplc-esi-ms analyses	executed the metabolite extraction and hplc-esi-ms analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5786554	29403524	LS	2	performed most of the experiments|conceptualized the overall structure of the experimental work and critically edited it|revised the text based on feedback from all the coauthors	performed most of the experiments	Performed the experiments	Investigation	YES
5786554	29403524	LS	2	performed most of the experiments|conceptualized the overall structure of the experimental work and critically edited it|revised the text based on feedback from all the coauthors	conceptualized the overall structure of the experimental work and critically edited it	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Review & Editing	YES
5786554	29403524	LS	2	performed most of the experiments|conceptualized the overall structure of the experimental work and critically edited it|revised the text based on feedback from all the coauthors	revised the text based on feedback from all the coauthors	Wrote the paper	Writing - Review & Editing	YES
5786554	29403524	MC	2	executed the metabolite extraction and hplc-esi-ms analyses	executed the metabolite extraction and hplc-esi-ms analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5786554	29403524	MRC	2	performed the measurements on lignification	performed the measurements on lignification	Performed the experiments	Investigation	YES
5786554	29403524	OV	2	performed most of the experiments|conceptualized the overall structure of the experimental work and critically edited it	performed most of the experiments	Performed the experiments	Investigation	YES
5786554	29403524	OV	2	performed most of the experiments|conceptualized the overall structure of the experimental work and critically edited it	conceptualized the overall structure of the experimental work and critically edited it	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Review & Editing	YES
5786554	29403524	SP	2	contributed to carry out the experiments on bacterial growth assays	contributed to carry out the experiments on bacterial growth assays	Performed the experiments	Investigation	YES
5599796	28739580	AJJ	2	analyzed the cryo-em data	analyzed the cryo-em data	Analyzed the data	Formal analysis	YES
5599796	28739580	CS	2	analyzed the cryo-em data	analyzed the cryo-em data	Analyzed the data	Formal analysis	YES
5599796	28739580	CWM	2	initiated and supervised the project|prepared the manuscript with input from all other authors	initiated and supervised the project	Conceived and designed the experiments	Conceptualization|Supervision	YES
5599796	28739580	CWM	2	initiated and supervised the project|prepared the manuscript with input from all other authors	prepared the manuscript with input from all other authors	Wrote the paper	Writing - Original Draft	YES
5599796	28739580	JK	2	carried out the modeling|prepared the manuscript with input from all other authors	carried out the modeling	Performed the experiments	Investigation|Methodology	YES
5599796	28739580	JK	2	carried out the modeling|prepared the manuscript with input from all other authors	prepared the manuscript with input from all other authors	Wrote the paper	Writing - Original Draft	YES
5599796	28739580	LT	2	designed and carried out experiments and data processing|analyzed the cryo-em data|carried out the modeling|prepared the manuscript with input from all other authors	designed and carried out experiments and data processing	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Data curation|Investigation|Methodology	YES
5599796	28739580	LT	2	designed and carried out experiments and data processing|analyzed the cryo-em data|carried out the modeling|prepared the manuscript with input from all other authors	analyzed the cryo-em data	Analyzed the data	Formal analysis	YES
5599796	28739580	LT	2	designed and carried out experiments and data processing|analyzed the cryo-em data|carried out the modeling|prepared the manuscript with input from all other authors	carried out the modeling	Performed the experiments	Investigation|Methodology	YES
5599796	28739580	LT	2	designed and carried out experiments and data processing|analyzed the cryo-em data|carried out the modeling|prepared the manuscript with input from all other authors	prepared the manuscript with input from all other authors	Wrote the paper	Writing - Original Draft	YES
5599796	28739580	MB	2	supervised the cross-linking experiment	supervised the cross-linking experiment	-	Supervision	YES
5599796	28739580	RW	2	carried out yeast fermentation and assisted in sample preparation	carried out yeast fermentation and assisted in sample preparation	Performed the experiments	Investigation	YES
5599796	28739580	WJHH	2	collected negative stain and cryo-em datasets	collected negative stain and cryo-em datasets	Performed the experiments	Investigation	YES
5599796	28739580	YS	2	designed and carried out experiments and data processing|collected negative stain and cryo-em datasets|analyzed the cryo-em data|carried out the modeling|prepared the manuscript with input from all other authors	designed and carried out experiments and data processing	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Data curation|Investigation|Methodology	YES
5599796	28739580	YS	2	designed and carried out experiments and data processing|collected negative stain and cryo-em datasets|analyzed the cryo-em data|carried out the modeling|prepared the manuscript with input from all other authors	collected negative stain and cryo-em datasets	Performed the experiments	Investigation	YES
5599796	28739580	YS	2	designed and carried out experiments and data processing|collected negative stain and cryo-em datasets|analyzed the cryo-em data|carried out the modeling|prepared the manuscript with input from all other authors	analyzed the cryo-em data	Analyzed the data	Formal analysis	YES
5599796	28739580	YS	2	designed and carried out experiments and data processing|collected negative stain and cryo-em datasets|analyzed the cryo-em data|carried out the modeling|prepared the manuscript with input from all other authors	carried out the modeling	Performed the experiments	Investigation|Methodology	YES
5599796	28739580	YS	2	designed and carried out experiments and data processing|collected negative stain and cryo-em datasets|analyzed the cryo-em data|carried out the modeling|prepared the manuscript with input from all other authors	prepared the manuscript with input from all other authors	Wrote the paper	Writing - Original Draft	YES
5709968	29191166	C Riverside	2	acquisition of relevant funding, writing the manuscript, and analyzing genomic content	acquisition of relevant funding, writing the manuscript, and analyzing genomic content	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Funding acquisition|Investigation|Writing - Original Draft	YES
5709968	29191166	DTA	2	established x	established x	-	-	NO
5709968	29191166	I-HK	2	carried out mosquitocidal toxin experiments and wrote portions of the manuscript	carried out mosquitocidal toxin experiments and wrote portions of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5709968	29191166	JCE	2	identified and completed preliminary characterization of the mosquitocidal toxin and acquired funding to obtain the genome sequence	identified and completed preliminary characterization of the mosquitocidal toxin and acquired funding to obtain the genome sequence	Performed the experiments	Funding acquisition|Investigation	YES
5709968	29191166	MARTX	2	other genomic elements, and writing of the manuscript	other genomic elements, and writing of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5709968	29191166	TJM	2	also conducted bacterial growth analyses and t3ss comparisons and helped write and edit the manuscript	also conducted bacterial growth analyses and t3ss comparisons and helped write and edit the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5709968	29191166	TPS	2	helped edit the manuscript	helped edit the manuscript	Wrote the paper	Writing - Review & Editing	YES
5709968	29191166	UTK	2	acquisition of funding, analysis of tps	acquisition of funding, analysis of tps	-	Funding acquisition	YES
1950077	17726517	DM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1950077	17726517	DM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1950077	17726517	DM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1950077	17726517	DM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1950077	17726517	DM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1950077	17726517	MB	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4628745	26557680	All authors	2	were involved in extensive discussions and wrote the paper	were involved in extensive discussions and wrote the paper	Wrote the paper	Writing - Original Draft	YES
4628745	26557680	Fernando Seoane	2	conceived and supervised the study	conceived and supervised the study	Conceived and designed the experiments	Conceptualization|Supervision	YES
4628745	26557680	Jens Tomner	2	collected the measurements from stroke patients|retrieved and processed the imaging and other medically relevant data from the patients	collected the measurements from stroke patients	Performed the experiments	Investigation	YES
4628745	26557680	Jens Tomner	2	collected the measurements from stroke patients|retrieved and processed the imaging and other medically relevant data from the patients	retrieved and processed the imaging and other medically relevant data from the patients	Analyzed the data	Data curation|Visualization	YES
4628745	26557680	Kaj Lindecrantz	2	conceived and supervised the study	conceived and supervised the study	Conceived and designed the experiments	Conceptualization|Supervision	YES
4628745	26557680	Konstantinos Kostulas	2	conceived and supervised the study|retrieved and processed the imaging and other medically relevant data from the patients	conceived and supervised the study	Conceived and designed the experiments	Conceptualization|Supervision	YES
4628745	26557680	Konstantinos Kostulas	2	conceived and supervised the study|retrieved and processed the imaging and other medically relevant data from the patients	retrieved and processed the imaging and other medically relevant data from the patients	Analyzed the data	Data curation|Visualization	YES
4628745	26557680	Reza Atefi	2	analyzed the data and produced the outline of paper and the figures	analyzed the data and produced the outline of paper and the figures	Analyzed the data	Formal analysis|Visualization	YES
5459781	28587444	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5459781	28587444	BSS	2	involved in the experimental design, data analysis, manuscript preparation, critical review of the results	involved in the experimental design, data analysis, manuscript preparation, critical review of the results	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5459781	28587444	CC	2	involved in the designing of the experiments, analysis of data, critical review of the manuscript, and support the manuscript writing	involved in the designing of the experiments, analysis of data, critical review of the manuscript, and support the manuscript writing	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5459781	28587444	NP	2	participated in the rsm study, phytochemical quantifications, and statistical analysis	participated in the rsm study, phytochemical quantifications, and statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5459781	28587444	SK	2	participated in the analytical part of the study	participated in the analytical part of the study	-	-	NO
5459781	28587444	SP	2	was responsible for acquiring the raw experimental data and processing	was responsible for acquiring the raw experimental data and processing	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5459781	28587444	SS	2	involved in the microbiological experiments	involved in the microbiological experiments	-	-	NO
4416048	25927526	CAE	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416048	25927526	CAE	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416048	25927526	CAE	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416048	25927526	CAE	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416048	25927526	EN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416048	25927526	EN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416048	25927526	EN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416048	25927526	EN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416048	25927526	EN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416048	25927526	ESL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416048	25927526	ESL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416048	25927526	ESL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416048	25927526	ESL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416048	25927526	ESL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416048	25927526	GSC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416048	25927526	GSC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416048	25927526	GSC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416048	25927526	GSC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416048	25927526	GSC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416048	25927526	LK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416048	25927526	LK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416048	25927526	LK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416048	25927526	LK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416048	25927526	LK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416048	25927526	MEC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416048	25927526	MEC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416048	25927526	MEC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416048	25927526	MEC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416048	25927526	MEC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416048	25927526	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416048	25927526	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416048	25927526	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416048	25927526	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416048	25927526	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416048	25927526	PMN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416048	25927526	PMN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416048	25927526	PMN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416048	25927526	PMN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416048	25927526	PMN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416048	25927526	RAO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416048	25927526	RAO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416048	25927526	RAO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416048	25927526	RAO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416048	25927526	RAO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416048	25927526	RHG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416048	25927526	RHG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416048	25927526	RHG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416048	25927526	RHG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416048	25927526	RHG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416048	25927526	SD	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416048	25927526	SD	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416048	25927526	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416048	25927526	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416048	25927526	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416048	25927526	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416048	25927526	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416048	25927526	TD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416048	25927526	TD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416048	25927526	TD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416048	25927526	TD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416048	25927526	TD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416048	25927526	VALT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416048	25927526	VALT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416048	25927526	VALT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416048	25927526	VALT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416048	25927526	VALT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4528818	26240421	Both authors	2	drafted and revised the manuscript and gave final approval for publication	drafted and revised the manuscript and gave final approval for publication	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5786559	29403509	DS	2	contributed to experimental design and generated data	contributed to experimental design and generated data	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources	YES
5786559	29403509	FC	2	supervised this work	supervised this work	-	Supervision	YES
5786559	29403509	GDL	2	contributed to experimental design and generated data|co-wrote the manuscript|supervised this work	contributed to experimental design and generated data	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources	YES
5786559	29403509	GDL	2	contributed to experimental design and generated data|co-wrote the manuscript|supervised this work	co-wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5786559	29403509	GDL	2	contributed to experimental design and generated data|co-wrote the manuscript|supervised this work	supervised this work	-	Supervision	YES
5786559	29403509	NG	2	contributed to experimental design and generated data|co-wrote the manuscript	contributed to experimental design and generated data	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources	YES
5786559	29403509	NG	2	contributed to experimental design and generated data|co-wrote the manuscript	co-wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5786559	29403509	TE	2	contributed with experimental data	contributed with experimental data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5914016	29713249	APTF	2	designed the study|performed the statistical analysis	designed the study	Conceived and designed the experiments	Methodology	YES
5914016	29713249	APTF	2	designed the study|performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
5914016	29713249	ARO	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5914016	29713249	All authors	2	helped to draft the manuscript, read and approved the final manuscript	helped to draft the manuscript, read and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5914016	29713249	GCS	2	carried out the data collection	carried out the data collection	Performed the experiments	Investigation	YES
5914016	29713249	JCFM	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5914016	29713249	JRF	2	carried out the data collection|performed the biochemical analyzes	carried out the data collection	Performed the experiments	Investigation	YES
5914016	29713249	JRF	2	carried out the data collection|performed the biochemical analyzes	performed the biochemical analyzes	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5914016	29713249	JSR	2	carried out the data collection|performed the biochemical analyzes	carried out the data collection	Performed the experiments	Investigation	YES
5914016	29713249	JSR	2	carried out the data collection|performed the biochemical analyzes	performed the biochemical analyzes	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5914016	29713249	KBS	2	designed the study|carried out the data collection|performed the statistical analysis	designed the study	Conceived and designed the experiments	Methodology	YES
5914016	29713249	KBS	2	designed the study|carried out the data collection|performed the statistical analysis	carried out the data collection	Performed the experiments	Investigation	YES
5914016	29713249	KBS	2	designed the study|carried out the data collection|performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
5914016	29713249	MK	2	designed the study|performed the biochemical analyzes	designed the study	Conceived and designed the experiments	Methodology	YES
5914016	29713249	MK	2	designed the study|performed the biochemical analyzes	performed the biochemical analyzes	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5914016	29713249	PIHB	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5914016	29713249	RF	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5914016	29713249	RR	2	carried out the data collection|performed the biochemical analyzes	carried out the data collection	Performed the experiments	Investigation	YES
5914016	29713249	RR	2	carried out the data collection|performed the biochemical analyzes	performed the biochemical analyzes	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
1950078	17726538	JI	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1950078	17726538	JI	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1950078	17726538	JI	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1950078	17726538	KB	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1950078	17726538	SG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1950078	17726538	SG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1950078	17726538	SG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1950078	17726538	SG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1950078	17726538	SG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1950078	17726538	SP	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1950078	17726538	SP	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5459784	28587440	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5459784	28587440	FLG	2	collected the samples, performed the experiments, analyzed the data, and wrote the paper	collected the samples, performed the experiments, analyzed the data, and wrote the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5459784	28587440	LHT	2	helped in performing the experiments and analyzed the data	helped in performing the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5459784	28587440	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5459784	28587440	YGC	2	helped in performing the experiments and analyzed the data	helped in performing the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5459784	28587440	YHH	2	critically analyzed the study and helped in drafting the article as well as edited the manuscript	critically analyzed the study and helped in drafting the article as well as edited the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5459784	28587440	YMF	2	critically analyzed the study and helped in drafting the article as well as edited the manuscript	critically analyzed the study and helped in drafting the article as well as edited the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5710090	29191157	JQJ	2	conceived the study|did data analysis and drafted the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5710090	29191157	JQJ	2	conceived the study|did data analysis and drafted the manuscript	did data analysis and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5710090	29191157	LX	2	did data analysis and drafted the manuscript	did data analysis and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5710090	29191157	NSM	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5710090	29191157	WB	2	did data analysis and drafted the manuscript	did data analysis and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5710090	29191157	WYJ	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5710090	29191157	XYC	2	conceived the study|revised the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5710090	29191157	XYC	2	conceived the study|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5710090	29191157	YL	2	did data analysis and drafted the manuscript	did data analysis and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4416049	25928718	XX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416049	25928718	XX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416049	25928718	XX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416049	25928718	XX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416049	25928718	YW	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5786564	29403512	all authors	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4628747	26557676	R.-L.	4	or analysis and interpretation of data were performed by|Drafting the paper or revising it critically for important intellectual content was done by|Final approval of the version to be submitted was performed by	or analysis and interpretation of data were performed by	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4628747	26557676	R.-L.	4	or analysis and interpretation of data were performed by|Drafting the paper or revising it critically for important intellectual content was done by|Final approval of the version to be submitted was performed by	Drafting the paper or revising it critically for important intellectual content was done by	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4628747	26557676	R.-L.	4	or analysis and interpretation of data were performed by|Drafting the paper or revising it critically for important intellectual content was done by|Final approval of the version to be submitted was performed by	Final approval of the version to be submitted was performed by	Performed the experiments	Investigation	YES
5599802	28724529	All authors	2	contributed text and figure panels to the manuscript|gave final approval for publication	contributed text and figure panels to the manuscript	Wrote the paper	Visualization|Writing - Original Draft	YES
5599802	28724529	All authors	2	contributed text and figure panels to the manuscript|gave final approval for publication	gave final approval for publication	-	-	NO
5599802	28724529	ES	2	performed the molecular laboratory work	performed the molecular laboratory work	Performed the experiments	Investigation	YES
5599802	28724529	LT	2	designed the study|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5599802	28724529	LT	2	designed the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5599802	28724529	MK	2	performed imaging experiments|analysed data	performed imaging experiments	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
5599802	28724529	MK	2	performed imaging experiments|analysed data	analysed data	Analyzed the data	Formal analysis	YES
5599802	28724529	NV	2	performed the molecular laboratory work|performed imaging experiments|designed the study|analysed data|wrote the manuscript	performed the molecular laboratory work	Performed the experiments	Investigation	YES
5599802	28724529	NV	2	performed the molecular laboratory work|performed imaging experiments|designed the study|analysed data|wrote the manuscript	performed imaging experiments	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
5599802	28724529	NV	2	performed the molecular laboratory work|performed imaging experiments|designed the study|analysed data|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5599802	28724529	NV	2	performed the molecular laboratory work|performed imaging experiments|designed the study|analysed data|wrote the manuscript	analysed data	Analyzed the data	Formal analysis	YES
5599802	28724529	NV	2	performed the molecular laboratory work|performed imaging experiments|designed the study|analysed data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5599802	28724529	PD	2	performed imaging experiments|designed the study|analysed data|wrote the manuscript	performed imaging experiments	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
5599802	28724529	PD	2	performed imaging experiments|designed the study|analysed data|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5599802	28724529	PD	2	performed imaging experiments|designed the study|analysed data|wrote the manuscript	analysed data	Analyzed the data	Formal analysis	YES
5599802	28724529	PD	2	performed imaging experiments|designed the study|analysed data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5599802	28724529	PK	2	analysed data	analysed data	Analyzed the data	Formal analysis	YES
5599802	28724529	YM	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5918575	29713250	AFS-J	2	perform the exercises test|carry out program training|edited and revised manuscript|approved the final version of the manuscript	perform the exercises test	Performed the experiments	Investigation	YES
5918575	29713250	AFS-J	2	perform the exercises test|carry out program training|edited and revised manuscript|approved the final version of the manuscript	carry out program training	Performed the experiments	Investigation	YES
5918575	29713250	AFS-J	2	perform the exercises test|carry out program training|edited and revised manuscript|approved the final version of the manuscript	edited and revised manuscript	Wrote the paper	Writing - Review & Editing	YES
5918575	29713250	AFS-J	2	perform the exercises test|carry out program training|edited and revised manuscript|approved the final version of the manuscript	approved the final version of the manuscript	-	-	NO
5918575	29713250	FD-J	2	perform the packaged and prepared the capsules containing the supplement or placebo	perform the packaged and prepared the capsules containing the supplement or placebo	Performed the experiments	Investigation	YES
5918575	29713250	FDJ	2	perform the exercises test|edited and revised manuscript|approved the final version of the manuscript	perform the exercises test	Performed the experiments	Investigation	YES
5918575	29713250	FDJ	2	perform the exercises test|edited and revised manuscript|approved the final version of the manuscript	edited and revised manuscript	Wrote the paper	Writing - Review & Editing	YES
5918575	29713250	FDJ	2	perform the exercises test|edited and revised manuscript|approved the final version of the manuscript	approved the final version of the manuscript	-	-	NO
5918575	29713250	JG-P	2	perform the exercises test|edited and revised manuscript|approved the final version of the manuscript	perform the exercises test	Performed the experiments	Investigation	YES
5918575	29713250	JG-P	2	perform the exercises test|edited and revised manuscript|approved the final version of the manuscript	edited and revised manuscript	Wrote the paper	Writing - Review & Editing	YES
5918575	29713250	JG-P	2	perform the exercises test|edited and revised manuscript|approved the final version of the manuscript	approved the final version of the manuscript	-	-	NO
5918575	29713250	JHL	2	perform the exercises test|carry out program training|realize data curation|edited and revised manuscript|approved the final version of the manuscript	perform the exercises test	Performed the experiments	Investigation	YES
5918575	29713250	JHL	2	perform the exercises test|carry out program training|realize data curation|edited and revised manuscript|approved the final version of the manuscript	carry out program training	Performed the experiments	Investigation	YES
5918575	29713250	JHL	2	perform the exercises test|carry out program training|realize data curation|edited and revised manuscript|approved the final version of the manuscript	realize data curation	Analyzed the data	Data curation	YES
5918575	29713250	JHL	2	perform the exercises test|carry out program training|realize data curation|edited and revised manuscript|approved the final version of the manuscript	edited and revised manuscript	Wrote the paper	Writing - Review & Editing	YES
5918575	29713250	JHL	2	perform the exercises test|carry out program training|realize data curation|edited and revised manuscript|approved the final version of the manuscript	approved the final version of the manuscript	-	-	NO
5918575	29713250	JLM-M	2	conceived and designed the study|perform the exercises test|realize data curation|writing the original manuscript|edited and revised manuscript|approved the final version of the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5918575	29713250	JLM-M	2	conceived and designed the study|perform the exercises test|realize data curation|writing the original manuscript|edited and revised manuscript|approved the final version of the manuscript	perform the exercises test	Performed the experiments	Investigation	YES
5918575	29713250	JLM-M	2	conceived and designed the study|perform the exercises test|realize data curation|writing the original manuscript|edited and revised manuscript|approved the final version of the manuscript	realize data curation	Analyzed the data	Data curation	YES
5918575	29713250	JLM-M	2	conceived and designed the study|perform the exercises test|realize data curation|writing the original manuscript|edited and revised manuscript|approved the final version of the manuscript	writing the original manuscript	Wrote the paper	Writing - Original Draft	YES
5918575	29713250	JLM-M	2	conceived and designed the study|perform the exercises test|realize data curation|writing the original manuscript|edited and revised manuscript|approved the final version of the manuscript	edited and revised manuscript	Wrote the paper	Writing - Review & Editing	YES
5918575	29713250	JLM-M	2	conceived and designed the study|perform the exercises test|realize data curation|writing the original manuscript|edited and revised manuscript|approved the final version of the manuscript	approved the final version of the manuscript	-	-	NO
5918575	29713250	MCL-E	2	perform the packaged and prepared the capsules containing the supplement or placebo|edited and revised manuscript|approved the final version of the manuscript	perform the packaged and prepared the capsules containing the supplement or placebo	Performed the experiments	Investigation	YES
5918575	29713250	MCL-E	2	perform the packaged and prepared the capsules containing the supplement or placebo|edited and revised manuscript|approved the final version of the manuscript	edited and revised manuscript	Wrote the paper	Writing - Review & Editing	YES
5918575	29713250	MCL-E	2	perform the packaged and prepared the capsules containing the supplement or placebo|edited and revised manuscript|approved the final version of the manuscript	approved the final version of the manuscript	-	-	NO
5918575	29713250	MVG-C	2	carry out program training|edited and revised manuscript|approved the final version of the manuscript	carry out program training	Performed the experiments	Investigation	YES
5918575	29713250	MVG-C	2	carry out program training|edited and revised manuscript|approved the final version of the manuscript	edited and revised manuscript	Wrote the paper	Writing - Review & Editing	YES
5918575	29713250	MVG-C	2	carry out program training|edited and revised manuscript|approved the final version of the manuscript	approved the final version of the manuscript	-	-	NO
5918575	29713250	PG-F	2	perform the exercises test|carry out program training|edited and revised manuscript|approved the final version of the manuscript	perform the exercises test	Performed the experiments	Investigation	YES
5918575	29713250	PG-F	2	perform the exercises test|carry out program training|edited and revised manuscript|approved the final version of the manuscript	carry out program training	Performed the experiments	Investigation	YES
5918575	29713250	PG-F	2	perform the exercises test|carry out program training|edited and revised manuscript|approved the final version of the manuscript	edited and revised manuscript	Wrote the paper	Writing - Review & Editing	YES
5918575	29713250	PG-F	2	perform the exercises test|carry out program training|edited and revised manuscript|approved the final version of the manuscript	approved the final version of the manuscript	-	-	NO
5918575	29713250	PV-H	2	perform the exercises test|perform the packaged and prepared the capsules containing the supplement or placebo|edited and revised manuscript|approved the final version of the manuscript	perform the exercises test	Performed the experiments	Investigation	YES
5918575	29713250	PV-H	2	perform the exercises test|perform the packaged and prepared the capsules containing the supplement or placebo|edited and revised manuscript|approved the final version of the manuscript	perform the packaged and prepared the capsules containing the supplement or placebo	Performed the experiments	Investigation	YES
5918575	29713250	PV-H	2	perform the exercises test|perform the packaged and prepared the capsules containing the supplement or placebo|edited and revised manuscript|approved the final version of the manuscript	edited and revised manuscript	Wrote the paper	Writing - Review & Editing	YES
5918575	29713250	PV-H	2	perform the exercises test|perform the packaged and prepared the capsules containing the supplement or placebo|edited and revised manuscript|approved the final version of the manuscript	approved the final version of the manuscript	-	-	NO
5918575	29713250	RD	2	conceived and designed the study|perform the exercises test|realize data curation|edited and revised manuscript|edited and revised manuscript|approved the final version of the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5918575	29713250	RD	2	conceived and designed the study|perform the exercises test|realize data curation|edited and revised manuscript|edited and revised manuscript|approved the final version of the manuscript	perform the exercises test	Performed the experiments	Investigation	YES
5918575	29713250	RD	2	conceived and designed the study|perform the exercises test|realize data curation|edited and revised manuscript|edited and revised manuscript|approved the final version of the manuscript	realize data curation	Analyzed the data	Data curation	YES
5918575	29713250	RD	2	conceived and designed the study|perform the exercises test|realize data curation|edited and revised manuscript|edited and revised manuscript|approved the final version of the manuscript	edited and revised manuscript	Wrote the paper	Writing - Review & Editing	YES
5918575	29713250	RD	2	conceived and designed the study|perform the exercises test|realize data curation|edited and revised manuscript|edited and revised manuscript|approved the final version of the manuscript	edited and revised manuscript	Wrote the paper	Writing - Review & Editing	YES
5918575	29713250	RD	2	conceived and designed the study|perform the exercises test|realize data curation|edited and revised manuscript|edited and revised manuscript|approved the final version of the manuscript	approved the final version of the manuscript	-	-	NO
1950079	17726540	AS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1950079	17726540	CL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1950079	17726540	DS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1950079	17726540	DS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1950079	17726540	DS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1950079	17726540	JK	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1950079	17726540	KJ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1950079	17726540	KP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1950079	17726540	KP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1950079	17726540	KP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1950079	17726540	LR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1950079	17726540	LR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1950079	17726540	LR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1950079	17726540	LR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1950079	17726540	MB	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1950079	17726540	MB	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1950079	17726540	MZ	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1950079	17726540	MZ	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1950079	17726540	NR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1950079	17726540	NR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1950079	17726540	NR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1950079	17726540	PK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1950079	17726540	PK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1950079	17726540	PK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1950079	17726540	WP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1950079	17726540	WP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1950079	17726540	WP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1950079	17726540	WP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1950079	17726540	WP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1950079	17726540	YG	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1950079	17726540	YG	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5712093	29197330	AC	2	conceived the project design, performed experimental design and wrote the manuscript	conceived the project design, performed experimental design and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Writing - Original Draft	YES
5712093	29197330	HC	2	performed all the experiments, the data analysis and wrote the manuscript	performed all the experiments, the data analysis and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5712093	29197330	MAE	2	conceived the project design, performed experimental design and wrote the manuscript	conceived the project design, performed experimental design and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Writing - Original Draft	YES
5712093	29197330	MFB	2	conceived the project design, performed experimental design and wrote the manuscript	conceived the project design, performed experimental design and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Writing - Original Draft	YES
5459786	28587443	Both authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5459786	28587443	HS	2	performed experimental work	performed experimental work	Performed the experiments	Investigation	YES
5459786	28587443	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
4416050	25928217	CMW	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416050	25928217	CMW	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416050	25928217	DH	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416050	25928217	JSMP	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416050	25928217	KHC	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416050	25928217	KHC	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4416050	25928217	KHC	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416050	25928217	KPC	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416050	25928217	LKPS	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416050	25928217	LY	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416050	25928217	LY	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416050	25928217	LY	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416050	25928217	PC	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416050	25928217	XW	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5921979	29719493	AFS	2	was involved in the conception, design, and acquisition and analysis of the data as well as drafting the manuscript	was involved in the conception, design, and acquisition and analysis of the data as well as drafting the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
5921979	29719493	AVJ	2	was involved in the design and analysis of the data	was involved in the design and analysis of the data	Conceived and designed the experiments|Analyzed the data	Formal analysis	YES
5921979	29719493	All authors	2	have given final approval of the version to be published	have given final approval of the version to be published	-	-	NO
5921979	29719493	CC	2	was involved in the conception and design	was involved in the conception and design	Conceived and designed the experiments	Conceptualization	YES
5921979	29719493	FJRH	2	was involved in the conception, design, and acquisition and analysis of the data as well as drafting the manuscript	was involved in the conception, design, and acquisition and analysis of the data as well as drafting the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
5921979	29719493	RAC	2	was involved in the conception, design, and acquisition and analysis of the data as well as drafting the manuscript	was involved in the conception, design, and acquisition and analysis of the data as well as drafting the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
4528826	26240429	A.B.B.	2	also analysed data	also analysed data	Analyzed the data	Formal analysis	YES
4528826	26240429	All authors	2	have revised this article critically and have approved the final version of the article	have revised this article critically and have approved the final version of the article	Wrote the paper	Writing - Review & Editing	YES
4528826	26240429	B.J.S.	2	designed the study, recruited and tested participants, and analysed and interpreted data|also conceived the study, managed the overall conduct of the study and interpreted data	designed the study, recruited and tested participants, and analysed and interpreted data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
4528826	26240429	B.J.S.	2	designed the study, recruited and tested participants, and analysed and interpreted data|also conceived the study, managed the overall conduct of the study and interpreted data	also conceived the study, managed the overall conduct of the study and interpreted data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Data curation|Formal analysis|Investigation|Project administration	YES
4528826	26240429	C.K.	2	designed the study, recruited and tested participants, and analysed and interpreted data|additionally edited the manuscript	designed the study, recruited and tested participants, and analysed and interpreted data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
4528826	26240429	C.K.	2	designed the study, recruited and tested participants, and analysed and interpreted data|additionally edited the manuscript	additionally edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
4528826	26240429	E.F.-E.	2	designed the study, assisted with interpretation of data analysis, facilitated recruitment and conducted clinical aspects of participant testing	designed the study, assisted with interpretation of data analysis, facilitated recruitment and conducted clinical aspects of participant testing	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
4528826	26240429	G.S.	2	analysed and interpreted data|additionally edited the manuscript	analysed and interpreted data	Analyzed the data	Formal analysis	YES
4528826	26240429	G.S.	2	analysed and interpreted data|additionally edited the manuscript	additionally edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
4528826	26240429	J.C.	2	designed the study, recruited and tested participants, and analysed and interpreted data|additionally edited the manuscript	designed the study, recruited and tested participants, and analysed and interpreted data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
4528826	26240429	J.C.	2	designed the study, recruited and tested participants, and analysed and interpreted data|additionally edited the manuscript	additionally edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
4528826	26240429	J.P.	2	designed the study and facilitated recruitment of participants	designed the study and facilitated recruitment of participants	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4528826	26240429	J.S.	2	designed the study and facilitated recruitment of participants	designed the study and facilitated recruitment of participants	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4528826	26240429	P.B.J.	2	designed the study and facilitated recruitment of participants	designed the study and facilitated recruitment of participants	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4528826	26240429	S.H.	2	designed the study and facilitated recruitment of participants	designed the study and facilitated recruitment of participants	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4528826	26240429	T.P.	2	programmed the memory game	programmed the memory game	Contributed reagents/materials/analysis tools	Software	YES
5712094	29197334	DML	2	conceived and designed the research|supervised the project as co-correspondence	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5712094	29197334	DML	2	conceived and designed the research|supervised the project as co-correspondence	supervised the project as co-correspondence	-	Supervision	YES
5712094	29197334	DSG	2	supervised the project as co-correspondence	supervised the project as co-correspondence	-	Supervision	YES
5712094	29197334	LL	2	contributed in the retrieval of genes and the analysis of qrt pcr results	contributed in the retrieval of genes and the analysis of qrt pcr results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5712094	29197334	MC	2	contributed in designing qrt pcr primers	contributed in designing qrt pcr primers	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5712094	29197334	MYS	2	contributed in designing qrt pcr primers	contributed in designing qrt pcr primers	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5712094	29197334	SXL	2	conceived and designed the research|performed the experiments and wrote the manuscript	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5712094	29197334	SXL	2	conceived and designed the research|performed the experiments and wrote the manuscript	performed the experiments and wrote the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5712094	29197334	WX	2	cultivated the plant materials and helped to analyze the physiological data	cultivated the plant materials and helped to analyze the physiological data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5712094	29197334	XLF	2	contributed in the retrieval of genes and the analysis of qrt pcr results	contributed in the retrieval of genes and the analysis of qrt pcr results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5712094	29197334	ZRS	2	revised the intellectual content of this manuscript	revised the intellectual content of this manuscript	Wrote the paper	Writing - Review & Editing	YES
5786567	29403525	JC	2	provided the analytical tools and managed the reagents	provided the analytical tools and managed the reagents	Contributed reagents/materials/analysis tools	Resources	YES
5786567	29403525	MC	2	contributed with valuable discussions	contributed with valuable discussions	-	-	NO
5786567	29403525	P-PL	2	performed the experiments and wrote the first draft	performed the experiments and wrote the first draft	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5786567	29403525	T-FY	2	conducted the bioinformatic work and performed the experiments	conducted the bioinformatic work and performed the experiments	Performed the experiments	Formal analysis|Investigation	YES
5786567	29403525	W-JZ	2	revised and edited the manuscript	revised and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5786567	29403525	Y-BZ	2	provided the analytical tools and managed the reagents	provided the analytical tools and managed the reagents	Contributed reagents/materials/analysis tools	Resources	YES
5786567	29403525	Y-JX	2	contributed with valuable discussions	contributed with valuable discussions	-	-	NO
5786567	29403525	Y-ZM	2	coordinated the project	coordinated the project	-	Project administration	YES
5786567	29403525	Z-SX	2	coordinated the project, conceived and designed the experiments, and edited the manuscript	coordinated the project, conceived and designed the experiments, and edited the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Review & Editing	YES
1950080	17726539	HH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1950080	17726539	HH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1950080	17726539	HH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1950080	17726539	SA	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1950080	17726539	SA	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5623844	28768717	AF	2	designed and coordinated the experiments and wrote the manuscript	designed and coordinated the experiments and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft	YES
5623844	28768717	CK	2	performed gene expression analysis	performed gene expression analysis	Performed the experiments	Investigation	YES
5623844	28768717	CM	2	performed electrophysiological measurements	performed electrophysiological measurements	Performed the experiments	Investigation	YES
5623844	28768717	EB	2	performed gene expression analysis	performed gene expression analysis	Performed the experiments	Investigation	YES
5623844	28768717	EBB	2	performed experiments in human neuronal progenitor cells	performed experiments in human neuronal progenitor cells	Performed the experiments	Investigation	YES
5623844	28768717	FS	2	designed and coordinated the experiments and wrote the manuscript	designed and coordinated the experiments and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft	YES
5623844	28768717	GJ	2	performed gene expression analysis	performed gene expression analysis	Performed the experiments	Investigation	YES
5623844	28768717	ID	2	provided post-mortem human brain tissue	provided post-mortem human brain tissue	Contributed reagents/materials/analysis tools	Resources	YES
5623844	28768717	JCP	2	performed experiments in human neuronal progenitor cells	performed experiments in human neuronal progenitor cells	Performed the experiments	Investigation	YES
5623844	28768717	MD	2	generated fmn2-egfp mice	generated fmn2-egfp mice	Performed the experiments	Investigation	YES
5623844	28768717	NR	2	performed electrophysiological measurements	performed electrophysiological measurements	Performed the experiments	Investigation	YES
5623844	28768717	PAZ	2	performed experiments in human neuronal progenitor cells	performed experiments in human neuronal progenitor cells	Performed the experiments	Investigation	YES
5623844	28768717	PP	2	performed electrophysiological measurements	performed electrophysiological measurements	Performed the experiments	Investigation	YES
5623844	28768717	RCA-B	2	performed most of the experiments	performed most of the experiments	Performed the experiments	Investigation	YES
5623844	28768717	SB	2	performed gene expression analysis	performed gene expression analysis	Performed the experiments	Investigation	YES
4416051	25928073	CS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416051	25928073	CS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416051	25928073	CS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416051	25928073	EJP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416051	25928073	EJP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416051	25928073	EJP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416051	25928073	EJP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416051	25928073	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416051	25928073	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416051	25928073	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416051	25928073	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416051	25928073	TVB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416051	25928073	TVB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416051	25928073	TVB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416051	25928073	TVB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5809574	28770408	HT	2	was involved in planning and leading the study, and interpretation of data	was involved in planning and leading the study, and interpretation of data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5809574	28770408	IY	2	was involved in planning the study, conduct of analysis, and interpretation of data	was involved in planning the study, conduct of analysis, and interpretation of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5809574	28770408	MH	2	were involved in establishing the manual for proper use in clinical trials relating to radionuclide therapy with radium-223	were involved in establishing the manual for proper use in clinical trials relating to radionuclide therapy with radium-223	-	-	NO
5809574	28770408	N Matsubara	2	was involved in drafting the manuscript	was involved in drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
5809574	28770408	SK	2	were involved in establishing the manual for proper use in clinical trials relating to radionuclide therapy with radium-223	were involved in establishing the manual for proper use in clinical trials relating to radionuclide therapy with radium-223	-	-	NO
5809574	28770408	all authors	2	contributed to reviewing the manuscript and approved the final version	contributed to reviewing the manuscript and approved the final version	Wrote the paper	Writing - Review & Editing	YES
4628749	26557673	Alfredo Ribelles	2	share the first place within the authors of this work	share the first place within the authors of this work	-	-	NO
4628749	26557673	Carmen Galbis-Estrada	2	share the first place within the authors of this work	share the first place within the authors of this work	-	-	NO
5461228	28591979	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5461228	28591979	CJ	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5461228	28591979	JF	PLoS52	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5461228	28591979	RQ	PLoS52	designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
5461228	28591979	XC	PLoS52	carried out the experiments|carried out the experiments|wrote the paper	carried out the experiments	Performed the experiments	Investigation	YES
5461228	28591979	XC	PLoS52	carried out the experiments|carried out the experiments|wrote the paper	carried out the experiments	Performed the experiments	Investigation	YES
5461228	28591979	XC	PLoS52	carried out the experiments|carried out the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5461228	28591979	XG	PLoS52	designed the research|obtained funding	designed the research	Conceived and designed the experiments	Methodology	YES
5461228	28591979	XG	PLoS52	designed the research|obtained funding	obtained funding	-	Funding acquisition	YES
5461228	28591979	XW	PLoS52	carried out the experiments|obtained funding	carried out the experiments	Performed the experiments	Investigation	YES
5461228	28591979	XW	PLoS52	carried out the experiments|obtained funding	obtained funding	-	Funding acquisition	YES
5461228	28591979	YF	PLoS52	carried out the experiments|wrote the paper	carried out the experiments	Performed the experiments	Investigation	YES
5461228	28591979	YF	PLoS52	carried out the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5461228	28591979	YL	PLoS52	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5930494	29743825	DLC	2	was involved in data collection, analysis, interpretation, drafting, revising, and giving the final approval for the manuscript	was involved in data collection, analysis, interpretation, drafting, revising, and giving the final approval for the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5930494	29743825	DNS	2	were involved in study conception, design, drafting, revising, and giving the final approval for the manuscript	were involved in study conception, design, drafting, revising, and giving the final approval for the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5930494	29743825	GRC	2	was involved in data analysis, interpretation, drafting, revising, and giving the final approval for the manuscript	was involved in data analysis, interpretation, drafting, revising, and giving the final approval for the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5930494	29743825	HHB	2	were involved in the study conception, design, data analysis, interpretation, drafting, revising, and giving the final approval for the manuscript	were involved in the study conception, design, data analysis, interpretation, drafting, revising, and giving the final approval for the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5930494	29743825	JSJ	2	were involved in study conception, design, drafting, revising, and giving the final approval for the manuscript	were involved in study conception, design, drafting, revising, and giving the final approval for the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5930494	29743825	LRB	2	were involved in the study conception, design, data analysis, interpretation, drafting, revising, and giving the final approval for the manuscript	were involved in the study conception, design, data analysis, interpretation, drafting, revising, and giving the final approval for the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
1950081	17726532	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1950081	17726532	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1950081	17726532	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1950081	17726532	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1950081	17726532	RD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1950081	17726532	RD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1950081	17726532	RD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416052	25928647	GR	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416052	25928647	GR	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416052	25928647	JDEG	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416052	25928647	JDEG	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416052	25928647	JM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416052	25928647	JM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416052	25928647	JM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416052	25928647	MP	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416052	25928647	SGH	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416052	25928647	SWG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416052	25928647	SWG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416052	25928647	SWG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416052	25928647	SWG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416052	25928647	ZMS	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416052	25928647	ZMS	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4571567	26323759	A.S.	2	analysed genomic data and performed phylogenetic analyses|wrote, and all authors have critically assessed and approved the manuscript	analysed genomic data and performed phylogenetic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4571567	26323759	A.S.	2	analysed genomic data and performed phylogenetic analyses|wrote, and all authors have critically assessed and approved the manuscript	wrote, and all authors have critically assessed and approved the manuscript	Wrote the paper	Writing - Original Draft	YES
4571567	26323759	C.T.-V.	2	provided hot spring sediments from the culex basin in yellowstone national park	provided hot spring sediments from the culex basin in yellowstone national park	-	-	NO
4571567	26323759	D.R.C.	2	provided hot spring sediments from the culex basin in yellowstone national park	provided hot spring sediments from the culex basin in yellowstone national park	-	-	NO
4571567	26323759	J.H.S.	2	performed, optimized and analysed single cell and metagenomic sequence assemblies|analysed genomic data and performed phylogenetic analyses|wrote, and all authors have critically assessed and approved the manuscript	performed, optimized and analysed single cell and metagenomic sequence assemblies	Performed the experiments	Investigation	YES
4571567	26323759	J.H.S.	2	performed, optimized and analysed single cell and metagenomic sequence assemblies|analysed genomic data and performed phylogenetic analyses|wrote, and all authors have critically assessed and approved the manuscript	analysed genomic data and performed phylogenetic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4571567	26323759	J.H.S.	2	performed, optimized and analysed single cell and metagenomic sequence assemblies|analysed genomic data and performed phylogenetic analyses|wrote, and all authors have critically assessed and approved the manuscript	wrote, and all authors have critically assessed and approved the manuscript	Wrote the paper	Writing - Original Draft	YES
4571567	26323759	K.Z.-N.	2	analysed genomic data and performed phylogenetic analyses|wrote, and all authors have critically assessed and approved the manuscript	analysed genomic data and performed phylogenetic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4571567	26323759	K.Z.-N.	2	analysed genomic data and performed phylogenetic analyses|wrote, and all authors have critically assessed and approved the manuscript	wrote, and all authors have critically assessed and approved the manuscript	Wrote the paper	Writing - Original Draft	YES
4571567	26323759	L.G.	2	analysed genomic data and performed phylogenetic analyses|wrote, and all authors have critically assessed and approved the manuscript	analysed genomic data and performed phylogenetic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4571567	26323759	L.G.	2	analysed genomic data and performed phylogenetic analyses|wrote, and all authors have critically assessed and approved the manuscript	wrote, and all authors have critically assessed and approved the manuscript	Wrote the paper	Writing - Original Draft	YES
4571567	26323759	L.J.	2	prepared sequencing libraries	prepared sequencing libraries	Performed the experiments	Investigation	YES
4571567	26323759	T.J.G.E.	2	conceived the study|analysed genomic data and performed phylogenetic analyses|wrote, and all authors have critically assessed and approved the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4571567	26323759	T.J.G.E.	2	conceived the study|analysed genomic data and performed phylogenetic analyses|wrote, and all authors have critically assessed and approved the manuscript	analysed genomic data and performed phylogenetic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4571567	26323759	T.J.G.E.	2	conceived the study|analysed genomic data and performed phylogenetic analyses|wrote, and all authors have critically assessed and approved the manuscript	wrote, and all authors have critically assessed and approved the manuscript	Wrote the paper	Writing - Original Draft	YES
5712110	29197323	All authors	2	contributed to the scope of the work, discussed and sanitized the results, and read and approved the final manuscript	contributed to the scope of the work, discussed and sanitized the results, and read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5712110	29197323	JG	2	contributed to the manuscript	contributed to the manuscript	-	-	NO
5712110	29197323	JHH	2	created some simulated data|wrote the manuscript	created some simulated data	-	Formal analysis	YES
5712110	29197323	JHH	2	created some simulated data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5712110	29197323	YK	2	implemented dotcoder and performed all computational experiments|wrote the manuscript	implemented dotcoder and performed all computational experiments	Performed the experiments	Formal analysis|Investigation	YES
5712110	29197323	YK	2	implemented dotcoder and performed all computational experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5930783	29743826	AL	2	devised the study|wrote the manuscript	devised the study	Conceived and designed the experiments	Conceptualization	YES
5930783	29743826	AL	2	devised the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5930783	29743826	All authors	2	were involved in data collection and/or analysis	were involved in data collection and/or analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5930783	29743826	MR	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5786577	29403508	All the authors	2	read and approved the final version of the manuscript	read and approved the final version of the manuscript	-	-	NO
5786577	29403508	EF	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5786577	29403508	JP	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5786577	29403508	ML	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5786577	29403508	TC	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5786577	29403508	The authors	2	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	Performed the experiments	Investigation	YES
5641678	28899900	AJB	2	provided the ret51 mice	provided the ret51 mice	Contributed reagents/materials/analysis tools	Resources	YES
5641678	28899900	DP	2	designed research	designed research	Conceived and designed the experiments	Methodology	YES
5641678	28899900	IM-A	2	designed research|wrote the manuscript	designed research	Conceived and designed the experiments	Methodology	YES
5641678	28899900	IM-A	2	designed research|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5641678	28899900	JAW	2	generated fly reagents	generated fly reagents	Performed the experiments	Investigation	YES
5641678	28899900	JK	2	generated fly reagents	generated fly reagents	Performed the experiments	Investigation	YES
5641678	28899900	NH	2	generated fly reagents	generated fly reagents	Performed the experiments	Investigation	YES
5641678	28899900	NT	2	provided the ret51 mice	provided the ret51 mice	Contributed reagents/materials/analysis tools	Resources	YES
5641678	28899900	PS	2	generated fly reagents	generated fly reagents	Performed the experiments	Investigation	YES
5641678	28899900	TC	2	analysed the rna seq isoform data	analysed the rna seq isoform data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5465227	28599506	All	2	materials and data used in this study have deposited in publicly available repositories	materials and data used in this study have deposited in publicly available repositories	-	-	NO
5465227	28599506	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5465227	28599506	G. Zheng	2	for assistance in petroleum sludge sampling and the analysis center in zhejiang university for assistance in mass spectrometry analyses	for assistance in petroleum sludge sampling and the analysis center in zhejiang university for assistance in mass spectrometry analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5465227	28599506	J. Xiao	2	for assistance in petroleum sludge sampling and the analysis center in zhejiang university for assistance in mass spectrometry analyses	for assistance in petroleum sludge sampling and the analysis center in zhejiang university for assistance in mass spectrometry analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5465227	28599506	JH	2	carried out the biological and biophysical studies	carried out the biological and biophysical studies	Performed the experiments	Investigation	YES
5465227	28599506	JLiang	2	carried out the analytic chemical studies	carried out the analytic chemical studies	Performed the experiments	Investigation	YES
5465227	28599506	JLiu	2	conceived the studies and participated in its design and coordination|drafted the manuscript	conceived the studies and participated in its design and coordination	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
5465227	28599506	JLiu	2	conceived the studies and participated in its design and coordination|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5465227	28599506	M.Sc	2	scholarships in zhejiang university ocean college	scholarships in zhejiang university ocean college	-	-	NO
5465227	28599506	Ph.D.	2	scholarships in zhejiang university ocean college	scholarships in zhejiang university ocean college	-	-	NO
5465227	28599506	TC	2	carried out the biological and biophysical studies	carried out the biological and biophysical studies	Performed the experiments	Investigation	YES
5465227	28599506	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5465227	28599506	XH	2	carried out the biological and biophysical studies	carried out the biological and biophysical studies	Performed the experiments	Investigation	YES
5465227	28599506	ZG	2	carried out the analytic chemical studies	carried out the analytic chemical studies	Performed the experiments	Investigation	YES
4416053	25928543	KVDV	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416053	25928543	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416053	25928543	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416053	25928543	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416053	25928543	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416053	25928543	MV	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4416053	25928543	MV	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416053	25928543	SB	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416053	25928543	SB	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416053	25928543	YB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416053	25928543	YB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416053	25928543	YB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4628751	26557682	Guangyang Weng	2	contributed equally to this work	contributed equally to this work	-	-	NO
4628751	26557682	Yingjian Zeng	2	contributed equally to this work	contributed equally to this work	-	-	NO
1950082	17712406	CF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1950082	17712406	CF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1950082	17712406	CF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1950082	17712406	CF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1950082	17712406	CF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4571569	26323761	S.G.	2	wrote the paper and prepared the figures	wrote the paper and prepared the figures	Wrote the paper	Visualization|Writing - Original Draft	YES
4571569	26323761	V.Z.	2	wrote the paper and prepared the figures	wrote the paper and prepared the figures	Wrote the paper	Visualization|Writing - Original Draft	YES
4571569	26323761	W.M.	2	wrote the paper and prepared the figures	wrote the paper and prepared the figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5712117	29197332	All authors	2	contributed to the conception and design of this study	contributed to the conception and design of this study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5712117	29197332	JL	2	collected tissue and performed rna extraction/ sequencing	collected tissue and performed rna extraction/ sequencing	Performed the experiments	Investigation	YES
5712117	29197332	LK	2	were major contributors to the writing of the manuscript	were major contributors to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5712117	29197332	ZH	2	were major contributors to the writing of the manuscript	were major contributors to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5641917	28923824	AL	2	performed experiments and analyzed data	performed experiments and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5641917	28923824	AS	2	conceived the study, supervised, analyzed data, and wrote the paper	conceived the study, supervised, analyzed data, and wrote the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Supervision|Writing - Original Draft	YES
5641917	28923824	BK	2	provided supervision	provided supervision	-	Supervision	YES
5641917	28923824	DG	2	performed experiments and analyzed data	performed experiments and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5641917	28923824	DM	2	performed experiments and analyzed data	performed experiments and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5641917	28923824	EK	2	designed and performed experiments, analyzed data, and wrote the paper	designed and performed experiments, analyzed data, and wrote the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5641917	28923824	KZ	2	performed experiments and analyzed data	performed experiments and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5641917	28923824	M-YS	2	performed experiments and analyzed data	performed experiments and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5641917	28923824	MMH	2	designed and performed experiments, analyzed data, and wrote the paper	designed and performed experiments, analyzed data, and wrote the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5641917	28923824	RF	2	performed experiments and analyzed data	performed experiments and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5641917	28923824	SB	2	performed experiments and analyzed data	performed experiments and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5641917	28923824	SR-J	2	provided supervision	provided supervision	-	Supervision	YES
5641917	28923824	TP	2	performed experiments and analyzed data	performed experiments and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5641917	28923824	VC	2	provided supervision	provided supervision	-	Supervision	YES
5932899	29743827	AHO	2	conceived the study, and participated in its design and coordination	conceived the study, and participated in its design and coordination	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
5932899	29743827	AM	2	performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
5932899	29743827	AMJF	2	designed the study|carried out the data collection|manufactured the test solutions|conceived the study, and participated in its design and coordination	designed the study	Conceived and designed the experiments	Methodology	YES
5932899	29743827	AMJF	2	designed the study|carried out the data collection|manufactured the test solutions|conceived the study, and participated in its design and coordination	carried out the data collection	Performed the experiments	Investigation	YES
5932899	29743827	AMJF	2	designed the study|carried out the data collection|manufactured the test solutions|conceived the study, and participated in its design and coordination	manufactured the test solutions	-	-	NO
5932899	29743827	AMJF	2	designed the study|carried out the data collection|manufactured the test solutions|conceived the study, and participated in its design and coordination	conceived the study, and participated in its design and coordination	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
5932899	29743827	APTF	2	designed the study|performed the statistical analysis|conceived the study, and participated in its design and coordination	designed the study	Conceived and designed the experiments	Methodology	YES
5932899	29743827	APTF	2	designed the study|performed the statistical analysis|conceived the study, and participated in its design and coordination	performed the statistical analysis	Analyzed the data	Formal analysis	YES
5932899	29743827	APTF	2	designed the study|performed the statistical analysis|conceived the study, and participated in its design and coordination	conceived the study, and participated in its design and coordination	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
5932899	29743827	All authors	2	helped to draft the manuscript, read and approved the final manuscript	helped to draft the manuscript, read and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5932899	29743827	HME	2	conceived the study, and participated in its design and coordination	conceived the study, and participated in its design and coordination	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
5932899	29743827	LFFJ	2	carried out the data collection|performed the statistical analysis	carried out the data collection	Performed the experiments	Investigation	YES
5932899	29743827	LFFJ	2	carried out the data collection|performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
5932899	29743827	TAA	2	carried out the data collection	carried out the data collection	Performed the experiments	Investigation	YES
5932899	29743827	TMAL	2	performed the biochemical analyzes	performed the biochemical analyzes	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4416702	25932954	P. Gan	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416702	25932954	P. Gan	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416702	25932954	P. Guo	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416702	25932954	P. Guo	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416702	25932954	P. Guo	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416702	25932954	WD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416702	25932954	WD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416702	25932954	WD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416702	25932954	WD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416702	25932954	WD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5466576	28605882	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5466576	28605882	CMN	2	made contributions to the interpretation of data and participated in revising the article	made contributions to the interpretation of data and participated in revising the article	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
5466576	28605882	CSl	2	carried out cultivation and expression experiments, purification and immobilization	carried out cultivation and expression experiments, purification and immobilization	Performed the experiments	Investigation	YES
5466576	28605882	CSy	2	made contributions to the interpretation of data and participated in revising the article	made contributions to the interpretation of data and participated in revising the article	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
5466576	28605882	GPS	2	carried out cultivation and expression experiments, assays of enzyme activity	carried out cultivation and expression experiments, assays of enzyme activity	Performed the experiments	Investigation	YES
5466576	28605882	JR	2	supervised the research work, made contributions to the interpretation of data and helped drafting and reviewing the manuscript	supervised the research work, made contributions to the interpretation of data and helped drafting and reviewing the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
5466576	28605882	MS	2	conducted the codon-optimization, provided different hydantoinase constructs and made contributions to the interpretation of data	conducted the codon-optimization, provided different hydantoinase constructs and made contributions to the interpretation of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5466576	28605882	PL	2	carried out cultivation and expression experiments	carried out cultivation and expression experiments	Performed the experiments	Investigation	YES
5466576	28605882	SDS-PAGE	2	analysis, assays of enzyme activity, establishment of hplc analysis as well as photometric assays and drafted the manuscript|analysis and analytical procedures|furthermore established the purification and immobilization via functionalized magnetic beads and participated in revising the article|analysis, assays of enzyme activity and analytical procedures	analysis, assays of enzyme activity, establishment of hplc analysis as well as photometric assays and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5466576	28605882	SDS-PAGE	2	analysis, assays of enzyme activity, establishment of hplc analysis as well as photometric assays and drafted the manuscript|analysis and analytical procedures|furthermore established the purification and immobilization via functionalized magnetic beads and participated in revising the article|analysis, assays of enzyme activity and analytical procedures	analysis and analytical procedures	Performed the experiments	Investigation	YES
5466576	28605882	SDS-PAGE	2	analysis, assays of enzyme activity, establishment of hplc analysis as well as photometric assays and drafted the manuscript|analysis and analytical procedures|furthermore established the purification and immobilization via functionalized magnetic beads and participated in revising the article|analysis, assays of enzyme activity and analytical procedures	furthermore established the purification and immobilization via functionalized magnetic beads and participated in revising the article	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5466576	28605882	SDS-PAGE	2	analysis, assays of enzyme activity, establishment of hplc analysis as well as photometric assays and drafted the manuscript|analysis and analytical procedures|furthermore established the purification and immobilization via functionalized magnetic beads and participated in revising the article|analysis, assays of enzyme activity and analytical procedures	analysis, assays of enzyme activity and analytical procedures	Performed the experiments	Investigation	YES
4628752	26557669	All authors	2	participated in the review and drafting and final approval of the paper	participated in the review and drafting and final approval of the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4628752	26557669	Chan Yun Kim	2	contributed equally to this work as co-first authors|designed data collection, analysed the data, and drafted and revised the paper	contributed equally to this work as co-first authors	-	-	NO
4628752	26557669	Chan Yun Kim	2	contributed equally to this work as co-first authors|designed data collection, analysed the data, and drafted and revised the paper	designed data collection, analysed the data, and drafted and revised the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
4628752	26557669	Da Yeong Kim	2	monitored data collection, analysed the data, and drafted the paper	monitored data collection, analysed the data, and drafted the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Supervision|Writing - Original Draft	YES
4628752	26557669	Jeong Hun Bae	2	designed data collection and cleaned and analysed the data	designed data collection and cleaned and analysed the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
4628752	26557669	Joon Mo Kim	2	designed data collection, monitored data collection, and revised the paper	designed data collection, monitored data collection, and revised the paper	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Review & Editing	YES
4628752	26557669	Ki Chul Sung	2	designed data collection, wrote the statistical analysis plan, cleaned and analysed the data, and revised the paper	designed data collection, wrote the statistical analysis plan, cleaned and analysed the data, and revised the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
4628752	26557669	Seong Hee Shim	2	contributed equally to this work as co-first authors|monitored data collection, analysed the data, and drafted the paper	contributed equally to this work as co-first authors	-	-	NO
4628752	26557669	Seong Hee Shim	2	contributed equally to this work as co-first authors|monitored data collection, analysed the data, and drafted the paper	monitored data collection, analysed the data, and drafted the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Supervision|Writing - Original Draft	YES
4628752	26557669	Yang Jae Kim	2	monitored data collection, analysed the data, and drafted the paper	monitored data collection, analysed the data, and drafted the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Supervision|Writing - Original Draft	YES
4571571	26323763	A.M.c.L.	2	analysed data and wrote the manuscript	analysed data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4571571	26323763	D.G.	2	analysed data and wrote the manuscript	analysed data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5786745	29403523	BD	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5786745	29403523	CJ	2	conducted the bioinformatics and phylogenetic analysis	conducted the bioinformatics and phylogenetic analysis	Performed the experiments	Formal analysis|Investigation	YES
5786745	29403523	HL	2	conducted the bioinformatics and phylogenetic analysis	conducted the bioinformatics and phylogenetic analysis	Performed the experiments	Formal analysis|Investigation	YES
5786745	29403523	JiG	2	conducted the bioinformatics and phylogenetic analysis|wrote the manuscript	conducted the bioinformatics and phylogenetic analysis	Performed the experiments	Formal analysis|Investigation	YES
5786745	29403523	JiG	2	conducted the bioinformatics and phylogenetic analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5786745	29403523	JuG	2	designed the experiment|wrote the manuscript	designed the experiment	Conceived and designed the experiments	Methodology	YES
5786745	29403523	JuG	2	designed the experiment|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5786745	29403523	MI	2	performed the gene expression and vigs experiments|wrote the manuscript	performed the gene expression and vigs experiments	Performed the experiments	Investigation	YES
5786745	29403523	MI	2	performed the gene expression and vigs experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5786745	29403523	PL	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5786745	29403523	QZ	2	conducted the bioinformatics and phylogenetic analysis	conducted the bioinformatics and phylogenetic analysis	Performed the experiments	Formal analysis|Investigation	YES
5786745	29403523	YD	2	performed the gene expression and vigs experiments	performed the gene expression and vigs experiments	Performed the experiments	Investigation	YES
5786745	29403523	ZK	2	designed the experiment|wrote the manuscript	designed the experiment	Conceived and designed the experiments	Methodology	YES
5786745	29403523	ZK	2	designed the experiment|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
1950083	17726533	AK	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1950083	17726533	KH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1950083	17726533	KH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1950083	17726533	KH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1950083	17726533	KH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1950083	17726533	KK	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1950083	17726533	KN	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1950083	17726533	KT	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1950083	17726533	MO	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1950083	17726533	MT	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1950083	17726533	TK	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1950083	17726533	TO	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1950083	17726533	YS	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416703	25933168	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416703	25933168	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4416703	25933168	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416703	25933168	CCH	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4416703	25933168	CCH	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416703	25933168	EMB	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416703	25933168	EMB	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416703	25933168	EMB	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416703	25933168	GJvG	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4416703	25933168	GJvG	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416703	25933168	LGV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416703	25933168	LGV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416703	25933168	LGV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416703	25933168	LGV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416703	25933168	LvL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4416703	25933168	LvL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416703	25933168	MCH	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416703	25933168	MCH	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416703	25933168	MvdVB	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4416703	25933168	MvdVB	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416703	25933168	RS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416703	25933168	RS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416703	25933168	RS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416703	25933168	RS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416703	25933168	RWS	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416703	25933168	RWS	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416703	25933168	RWS	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416703	25933168	WG	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4416703	25933168	WG	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5952515	29764464	All	2	authors approve of, and contributed to writing, the manuscript	authors approve of, and contributed to writing, the manuscript	Wrote the paper	Writing - Original Draft	YES
5952515	29764464	JMD	2	implemented the study, conducted testing, and collected data	implemented the study, conducted testing, and collected data	Performed the experiments	Investigation	YES
5952515	29764464	JMJ	2	implemented the study, conducted testing, and collected data|authors approve of, and contributed to writing, the manuscript	implemented the study, conducted testing, and collected data	Performed the experiments	Investigation	YES
5952515	29764464	JMJ	2	implemented the study, conducted testing, and collected data|authors approve of, and contributed to writing, the manuscript	authors approve of, and contributed to writing, the manuscript	Wrote the paper	Writing - Original Draft	YES
5952515	29764464	NMD	2	authors approve of, and contributed to writing, the manuscript	authors approve of, and contributed to writing, the manuscript	Wrote the paper	Writing - Original Draft	YES
5952515	29764464	NYK	2	implemented the study, conducted testing, and collected data	implemented the study, conducted testing, and collected data	Performed the experiments	Investigation	YES
5952515	29764464	RECW	2	authors approve of, and contributed to writing, the manuscript	authors approve of, and contributed to writing, the manuscript	Wrote the paper	Writing - Original Draft	YES
5952515	29764464	RMV	2	implemented the study, conducted testing, and collected data|authors approve of, and contributed to writing, the manuscript	implemented the study, conducted testing, and collected data	Performed the experiments	Investigation	YES
5952515	29764464	RMV	2	implemented the study, conducted testing, and collected data|authors approve of, and contributed to writing, the manuscript	authors approve of, and contributed to writing, the manuscript	Wrote the paper	Writing - Original Draft	YES
5712127	29197336	DF	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5712127	29197336	EW	PLoS52	analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5712127	29197336	EW	PLoS52	analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5712127	29197336	JW	PLoS52	designed the study|purified samples for ms analysis|analyzed the data|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5712127	29197336	JW	PLoS52	designed the study|purified samples for ms analysis|analyzed the data|wrote the manuscript	purified samples for ms analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5712127	29197336	JW	PLoS52	designed the study|purified samples for ms analysis|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5712127	29197336	JW	PLoS52	designed the study|purified samples for ms analysis|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5712127	29197336	KB	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5712127	29197336	SD	PLoS52	designed the study|analyzed the data|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5712127	29197336	SD	PLoS52	designed the study|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5712127	29197336	SD	PLoS52	designed the study|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5712127	29197336	TLK	PLoS52	designed the study|purified samples for ms analysis|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5712127	29197336	TLK	PLoS52	designed the study|purified samples for ms analysis|wrote the manuscript	purified samples for ms analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5712127	29197336	TLK	PLoS52	designed the study|purified samples for ms analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
1950084	17726534	BS	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1950084	17726534	FD	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1950084	17726534	FS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1950084	17726534	HK	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1950084	17726534	KK	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1950084	17726534	KK	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1950084	17726534	KL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1950084	17726534	KP	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1950084	17726534	LP	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1950084	17726534	SN	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1950084	17726534	SQ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1950084	17726534	TL	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1950084	17726534	TL	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1950084	17726534	TP	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1950084	17726534	TP	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1950084	17726534	WC	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1950084	17726534	YL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5786853	29403514	AS	PLoS52	conceived and designed the experiments|critically revised the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5786853	29403514	AS	PLoS52	conceived and designed the experiments|critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5786853	29403514	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5786853	29403514	BG	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5786853	29403514	KS	PLoS52	conceived and designed the experiments|critically revised the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5786853	29403514	KS	PLoS52	conceived and designed the experiments|critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5786853	29403514	PJ	PLoS52	conceived and designed the experiments|critically revised the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5786853	29403514	PJ	PLoS52	conceived and designed the experiments|critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5786853	29403514	SB	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5786853	29403514	SB	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5786853	29403514	SB	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5786853	29403514	SB	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5786853	29403514	SG	PLoS52	conceived and designed the experiments|critically revised the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5786853	29403514	SG	PLoS52	conceived and designed the experiments|critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5641919	28864543	AW	2	grew crystals, collected data, built and refined the structures	grew crystals, collected data, built and refined the structures	Performed the experiments	Investigation	YES
5641919	28864543	DPT	2	performed and analysed molecular simulations	performed and analysed molecular simulations	Performed the experiments	Formal analysis|Investigation	YES
5641919	28864543	GH	2	performed peldor measurements and analysis	performed peldor measurements and analysis	Performed the experiments	Investigation	YES
5641919	28864543	HGC	2	grew crystals, collected data, built and refined the structures|prepared proteins for peldor measurements	grew crystals, collected data, built and refined the structures	Performed the experiments	Investigation	YES
5641919	28864543	HGC	2	grew crystals, collected data, built and refined the structures|prepared proteins for peldor measurements	prepared proteins for peldor measurements	Performed the experiments	Investigation	YES
5641919	28864543	IM	2	grew crystals, collected data, built and refined the structures	grew crystals, collected data, built and refined the structures	Performed the experiments	Investigation	YES
5641919	28864543	KBe	2	designed and managed the overall project|grew crystals, collected data, built and refined the structures|wrote the manuscript with help from the other authors	designed and managed the overall project	Conceived and designed the experiments	Methodology|Project administration	YES
5641919	28864543	KBe	2	designed and managed the overall project|grew crystals, collected data, built and refined the structures|wrote the manuscript with help from the other authors	grew crystals, collected data, built and refined the structures	Performed the experiments	Investigation	YES
5641919	28864543	KBe	2	designed and managed the overall project|grew crystals, collected data, built and refined the structures|wrote the manuscript with help from the other authors	wrote the manuscript with help from the other authors	Wrote the paper	Writing - Original Draft	YES
5641919	28864543	KBo	2	grew crystals, collected data, built and refined the structures|performed pegylation, cross-linking experiments and transport assays|prepared proteins for peldor measurements	grew crystals, collected data, built and refined the structures	Performed the experiments	Investigation	YES
5641919	28864543	KBo	2	grew crystals, collected data, built and refined the structures|performed pegylation, cross-linking experiments and transport assays|prepared proteins for peldor measurements	performed pegylation, cross-linking experiments and transport assays	Performed the experiments	Investigation	YES
5641919	28864543	KBo	2	grew crystals, collected data, built and refined the structures|performed pegylation, cross-linking experiments and transport assays|prepared proteins for peldor measurements	prepared proteins for peldor measurements	Performed the experiments	Investigation	YES
5641919	28864543	KEO	2	grew crystals, collected data, built and refined the structures	grew crystals, collected data, built and refined the structures	Performed the experiments	Investigation	YES
5641919	28864543	OS	2	performed peldor measurements and analysis	performed peldor measurements and analysis	Performed the experiments	Investigation	YES
5641919	28864543	SR	2	produced and purified the mccj25	produced and purified the mccj25	Performed the experiments	Investigation	YES
5641919	28864543	SZ	2	produced and purified the mccj25	produced and purified the mccj25	Performed the experiments	Investigation	YES
5641919	28864543	VC	2	performed and analysed molecular simulations	performed and analysed molecular simulations	Performed the experiments	Formal analysis|Investigation	YES
5641919	28864543	WYW	2	performed pegylation, cross-linking experiments and transport assays|prepared proteins for peldor measurements	performed pegylation, cross-linking experiments and transport assays	Performed the experiments	Investigation	YES
5641919	28864543	WYW	2	performed pegylation, cross-linking experiments and transport assays|prepared proteins for peldor measurements	prepared proteins for peldor measurements	Performed the experiments	Investigation	YES
5466577	28605881	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5466577	28605881	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
1950085	17726535	DM	CRediT	Analyzed the data|Critical revision of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
1950085	17726535	DM	CRediT	Analyzed the data|Critical revision of the manuscript	Critical revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
1950085	17726535	KS	CRediT	Critical revision of the manuscript	Critical revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
1950085	17726535	MP	CRediT	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Critical revision of the manuscript|Supervision|Lead investigator	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1950085	17726535	MP	CRediT	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Critical revision of the manuscript|Supervision|Lead investigator	Analyzed the data	Analyzed the data	Formal analysis	YES
1950085	17726535	MP	CRediT	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Critical revision of the manuscript|Supervision|Lead investigator	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1950085	17726535	MP	CRediT	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Critical revision of the manuscript|Supervision|Lead investigator	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1950085	17726535	MP	CRediT	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Critical revision of the manuscript|Supervision|Lead investigator	Critical revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
1950085	17726535	MP	CRediT	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Critical revision of the manuscript|Supervision|Lead investigator	Supervision	-	Supervision	YES
1950085	17726535	MP	CRediT	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Critical revision of the manuscript|Supervision|Lead investigator	Lead investigator	-	-	NO
1950085	17726535	RJ	CRediT	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Critical revision of the manuscript|Supervised conduct of the study|Project manager	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1950085	17726535	RJ	CRediT	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Critical revision of the manuscript|Supervised conduct of the study|Project manager	Performed the experiments	Performed the experiments	Investigation	YES
1950085	17726535	RJ	CRediT	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Critical revision of the manuscript|Supervised conduct of the study|Project manager	Analyzed the data	Analyzed the data	Formal analysis	YES
1950085	17726535	RJ	CRediT	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Critical revision of the manuscript|Supervised conduct of the study|Project manager	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1950085	17726535	RJ	CRediT	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Critical revision of the manuscript|Supervised conduct of the study|Project manager	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1950085	17726535	RJ	CRediT	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Critical revision of the manuscript|Supervised conduct of the study|Project manager	Critical revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
1950085	17726535	RJ	CRediT	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Critical revision of the manuscript|Supervised conduct of the study|Project manager	Supervised conduct of the study	Performed the experiments	Investigation|Supervision	YES
1950085	17726535	RJ	CRediT	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Critical revision of the manuscript|Supervised conduct of the study|Project manager	Project manager	-	Project administration	YES
1950085	17726535	SK	CRediT	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Critical revision of the manuscript|Supervision	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1950085	17726535	SK	CRediT	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Critical revision of the manuscript|Supervision	Performed the experiments	Performed the experiments	Investigation	YES
1950085	17726535	SK	CRediT	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Critical revision of the manuscript|Supervision	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1950085	17726535	SK	CRediT	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Critical revision of the manuscript|Supervision	Critical revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
1950085	17726535	SK	CRediT	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Critical revision of the manuscript|Supervision	Supervision	-	Supervision	YES
1950085	17726535	SP	CRediT	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1950085	17726535	SP	CRediT	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5787072	29410674	CA-R	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5787072	29410674	EQ-M	PLoS52	designed the experiments|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5787072	29410674	EQ-M	PLoS52	designed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5787072	29410674	IG	PLoS52	designed the experiments|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5787072	29410674	IG	PLoS52	designed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5787072	29410674	JM	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5787072	29410674	MY	PLoS52	designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5787072	29410674	MY	PLoS52	designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5787072	29410674	MY	PLoS52	designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5787072	29410674	MY	PLoS52	designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5787072	29410674	PV-G	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5787072	29410674	SR	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5469723	28618714	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5469723	28618714	FQL	2	conceived the study, and participated in its design and coordination and helped to draft the manuscript	conceived the study, and participated in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
5469723	28618714	GLQ	2	conceived the study, and participated in its design and coordination and helped to draft the manuscript	conceived the study, and participated in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
5469723	28618714	GY	2	conceived the study, and participated in its design and coordination and helped to draft the manuscript	conceived the study, and participated in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
5469723	28618714	HYX	2	carried out the molecular genetic studies, participated in the sequence alignment and the design of the study	carried out the molecular genetic studies, participated in the sequence alignment and the design of the study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5469723	28618714	JZ	2	performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
5469723	28618714	RPW	2	carried out the molecular genetic studies, participated in the sequence alignment and drafted the manuscript	carried out the molecular genetic studies, participated in the sequence alignment and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5469723	28618714	YYZ	2	performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
4571573	26323765	A.A.D.	2	reconstructed phylogenies in fungi and performed all count analyses	reconstructed phylogenies in fungi and performed all count analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4571573	26323765	All authors	2	performed analyses and contributed to the writing of the article	performed analyses and contributed to the writing of the article	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5712148	29197325	BR	2	collected the data|advised on the data analyses and edited the manuscript	collected the data	Performed the experiments	Investigation	YES
5712148	29197325	BR	2	collected the data|advised on the data analyses and edited the manuscript	advised on the data analyses and edited the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5712148	29197325	CC	2	advised on the data analyses and edited the manuscript	advised on the data analyses and edited the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5712148	29197325	FRT	2	collected the data|performed the data analyses and wrote the manuscript	collected the data	Performed the experiments	Investigation	YES
5712148	29197325	FRT	2	collected the data|performed the data analyses and wrote the manuscript	performed the data analyses and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5712148	29197325	IP	2	collected the data|advised on the data analyses and edited the manuscript	collected the data	Performed the experiments	Investigation	YES
5712148	29197325	IP	2	collected the data|advised on the data analyses and edited the manuscript	advised on the data analyses and edited the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5712148	29197325	JK	2	advised on the data analyses and edited the manuscript	advised on the data analyses and edited the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5712148	29197325	MUS	2	conceived and designed the experiment|advised on the data analyses and edited the manuscript	conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5712148	29197325	MUS	2	conceived and designed the experiment|advised on the data analyses and edited the manuscript	advised on the data analyses and edited the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5712148	29197325	YAK	2	conceived and designed the experiment|advised on the data analyses and edited the manuscript	conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5712148	29197325	YAK	2	conceived and designed the experiment|advised on the data analyses and edited the manuscript	advised on the data analyses and edited the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5984413	29855372	AC	2	collected all data presented in this analysis|edited the manuscript	collected all data presented in this analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5984413	29855372	AC	2	collected all data presented in this analysis|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5984413	29855372	NB	2	collected all data presented in this analysis|analyzed and interpreted data results|prepared tables, figures, and drafted manuscript|edited the manuscript	collected all data presented in this analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5984413	29855372	NB	2	collected all data presented in this analysis|analyzed and interpreted data results|prepared tables, figures, and drafted manuscript|edited the manuscript	analyzed and interpreted data results	Analyzed the data	Formal analysis	YES
5984413	29855372	NB	2	collected all data presented in this analysis|analyzed and interpreted data results|prepared tables, figures, and drafted manuscript|edited the manuscript	prepared tables, figures, and drafted manuscript	Wrote the paper	Visualization|Writing - Original Draft	YES
5984413	29855372	NB	2	collected all data presented in this analysis|analyzed and interpreted data results|prepared tables, figures, and drafted manuscript|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5984413	29855372	RK	2	edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
4416704	25933440	CH	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416704	25933440	CW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416704	25933440	CW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416704	25933440	CW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416704	25933440	NM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416704	25933440	NM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416704	25933440	NM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416704	25933440	NM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416704	25933440	NM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416704	25933440	PA	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416704	25933440	PY	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4416704	25933440	PY	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416704	25933440	YB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416704	25933440	YG	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4416704	25933440	YG	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416704	25933440	YL	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416704	25933440	YZ	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4416704	25933440	YZ	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416704	25933440	ZJ	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4416704	25933440	ZJ	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5666619	29030484	AC	PLoS52	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5666619	29030484	MS	PLoS52	analyzed the data|designed the study and wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5666619	29030484	MS	PLoS52	analyzed the data|designed the study and wrote the manuscript	designed the study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5666619	29030484	PR-R	PLoS52	performed the experiments and analyzed the data|designed the study and wrote the manuscript	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5666619	29030484	PR-R	PLoS52	performed the experiments and analyzed the data|designed the study and wrote the manuscript	designed the study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5666619	29030484	SP	PLoS52	performed bioinformatic analyses	performed bioinformatic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5666619	29030484	all authors	PLoS52	discussed the manuscript	discussed the manuscript	-	-	NO
5984464	29855319	ADE	2	analyzed data|interpreted results of experiments|prepared figures|drafted manuscript|approved final version of manuscript	analyzed data	Analyzed the data	Formal analysis	YES
5984464	29855319	ADE	2	analyzed data|interpreted results of experiments|prepared figures|drafted manuscript|approved final version of manuscript	interpreted results of experiments	Analyzed the data	Formal analysis	YES
5984464	29855319	ADE	2	analyzed data|interpreted results of experiments|prepared figures|drafted manuscript|approved final version of manuscript	prepared figures	-	Visualization	YES
5984464	29855319	ADE	2	analyzed data|interpreted results of experiments|prepared figures|drafted manuscript|approved final version of manuscript	drafted manuscript	Wrote the paper	Writing - Original Draft	YES
5984464	29855319	ADE	2	analyzed data|interpreted results of experiments|prepared figures|drafted manuscript|approved final version of manuscript	approved final version of manuscript	-	-	NO
5984464	29855319	ML	2	conception and design of research|performed experiments|analyzed data|interpreted results of experiments|prepared figures|drafted manuscript|edited and revised manuscript|approved final version of manuscript	conception and design of research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5984464	29855319	ML	2	conception and design of research|performed experiments|analyzed data|interpreted results of experiments|prepared figures|drafted manuscript|edited and revised manuscript|approved final version of manuscript	performed experiments	Performed the experiments	Investigation	YES
5984464	29855319	ML	2	conception and design of research|performed experiments|analyzed data|interpreted results of experiments|prepared figures|drafted manuscript|edited and revised manuscript|approved final version of manuscript	analyzed data	Analyzed the data	Formal analysis	YES
5984464	29855319	ML	2	conception and design of research|performed experiments|analyzed data|interpreted results of experiments|prepared figures|drafted manuscript|edited and revised manuscript|approved final version of manuscript	interpreted results of experiments	Analyzed the data	Formal analysis	YES
5984464	29855319	ML	2	conception and design of research|performed experiments|analyzed data|interpreted results of experiments|prepared figures|drafted manuscript|edited and revised manuscript|approved final version of manuscript	prepared figures	-	Visualization	YES
5984464	29855319	ML	2	conception and design of research|performed experiments|analyzed data|interpreted results of experiments|prepared figures|drafted manuscript|edited and revised manuscript|approved final version of manuscript	drafted manuscript	Wrote the paper	Writing - Original Draft	YES
5984464	29855319	ML	2	conception and design of research|performed experiments|analyzed data|interpreted results of experiments|prepared figures|drafted manuscript|edited and revised manuscript|approved final version of manuscript	edited and revised manuscript	Wrote the paper	Writing - Review & Editing	YES
5984464	29855319	ML	2	conception and design of research|performed experiments|analyzed data|interpreted results of experiments|prepared figures|drafted manuscript|edited and revised manuscript|approved final version of manuscript	approved final version of manuscript	-	-	NO
5984464	29855319	PP	2	conception and design of research|performed experiments|interpreted results of experiments|edited and revised manuscript|approved final version of manuscript	conception and design of research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5984464	29855319	PP	2	conception and design of research|performed experiments|interpreted results of experiments|edited and revised manuscript|approved final version of manuscript	performed experiments	Performed the experiments	Investigation	YES
5984464	29855319	PP	2	conception and design of research|performed experiments|interpreted results of experiments|edited and revised manuscript|approved final version of manuscript	interpreted results of experiments	Analyzed the data	Formal analysis	YES
5984464	29855319	PP	2	conception and design of research|performed experiments|interpreted results of experiments|edited and revised manuscript|approved final version of manuscript	edited and revised manuscript	Wrote the paper	Writing - Review & Editing	YES
5984464	29855319	PP	2	conception and design of research|performed experiments|interpreted results of experiments|edited and revised manuscript|approved final version of manuscript	approved final version of manuscript	-	-	NO
1950086	17726536	AA	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1950086	17726536	AA	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1950086	17726536	JM	PLoS5	Contributed reagents/materials/analysis tools|Financial support	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1950086	17726536	JM	PLoS5	Contributed reagents/materials/analysis tools|Financial support	Financial support	-	Funding acquisition	YES
1950086	17726536	MK	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1950086	17726536	NS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1950086	17726536	SY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Principal investigator	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1950086	17726536	SY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Principal investigator	Performed the experiments	Performed the experiments	Investigation	YES
1950086	17726536	SY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Principal investigator	Analyzed the data	Analyzed the data	Formal analysis	YES
1950086	17726536	SY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Principal investigator	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1950086	17726536	SY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Principal investigator	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1950086	17726536	SY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Principal investigator	Principal investigator	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
1950086	17726536	YO	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416705	25932913	CHD	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4416705	25932913	CHD	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4416705	25932913	CHD	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416705	25932913	CHH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4416705	25932913	CHH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4416705	25932913	CHH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416705	25932913	FC	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4416705	25932913	FC	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4416705	25932913	FC	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416705	25932913	HS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4416705	25932913	HS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4416705	25932913	HS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416705	25932913	JFL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4416705	25932913	JFL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4416705	25932913	JFL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416705	25932913	MHW	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4416705	25932913	MHW	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4416705	25932913	MHW	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416705	25932913	SJ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4416705	25932913	SJ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4416705	25932913	SJ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416705	25932913	SY	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416705	25932913	SY	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416705	25932913	SY	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416705	25932913	WWZ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416705	25932913	WWZ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416705	25932913	WWZ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5787091	29410675	AK	2	wrote the review manuscript|critically reviewed the manuscript and supervised the manuscript drafting	wrote the review manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5787091	29410675	AK	2	wrote the review manuscript|critically reviewed the manuscript and supervised the manuscript drafting	critically reviewed the manuscript and supervised the manuscript drafting	Wrote the paper	Supervision|Writing - Original Draft|Writing - Review & Editing	YES
5787091	29410675	I-JL	2	critically reviewed the manuscript and supervised the manuscript drafting	critically reviewed the manuscript and supervised the manuscript drafting	Wrote the paper	Supervision|Writing - Original Draft|Writing - Review & Editing	YES
5787091	29410675	RS	2	design the study|wrote the review manuscript	design the study	Conceived and designed the experiments	Methodology	YES
5787091	29410675	RS	2	design the study|wrote the review manuscript	wrote the review manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5787091	29410675	SA	2	wrote the review manuscript	wrote the review manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5787091	29410675	SB	2	wrote the review manuscript	wrote the review manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5471287	27080227	AJ	2	provided conceptual and technical guidance for all aspects of the manuscript	provided conceptual and technical guidance for all aspects of the manuscript	Conceived and designed the experiments	Conceptualization|Supervision	YES
5471287	27080227	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5471287	27080227	GM	2	designed and carried out the molecular studies|analyzed the data for comparative sequence studies	designed and carried out the molecular studies	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5471287	27080227	GM	2	designed and carried out the molecular studies|analyzed the data for comparative sequence studies	analyzed the data for comparative sequence studies	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5471287	27080227	MIR	2	designed and carried out the molecular studies	designed and carried out the molecular studies	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5712200	29197344	HL	2	contributed to the design of the study and discussed the results	contributed to the design of the study and discussed the results	Conceived and designed the experiments	Methodology	YES
5712200	29197344	HS	2	contributed to the design of the study and discussed the results|performed rumen fluid, serum, urine and milk samples collection and collected mammary gland tissue samples	contributed to the design of the study and discussed the results	Conceived and designed the experiments	Methodology	YES
5712200	29197344	HS	2	contributed to the design of the study and discussed the results|performed rumen fluid, serum, urine and milk samples collection and collected mammary gland tissue samples	performed rumen fluid, serum, urine and milk samples collection and collected mammary gland tissue samples	Performed the experiments	Investigation	YES
5712200	29197344	JL	2	contributed to the design of the study and discussed the results	contributed to the design of the study and discussed the results	Conceived and designed the experiments	Methodology	YES
5712200	29197344	SK	2	helped analysis mammary gland metabolomics data	helped analysis mammary gland metabolomics data	Analyzed the data	Formal analysis	YES
5712200	29197344	ZW	2	performed rumen fluid, serum, urine and milk samples collection and collected mammary gland tissue samples	performed rumen fluid, serum, urine and milk samples collection and collected mammary gland tissue samples	Performed the experiments	Investigation	YES
4571574	26323766	All authors	2	commented on and approved the final version of the paper	commented on and approved the final version of the paper	-	-	NO
4571574	26323766	R.J.B.	2	devised and implemented the hb model|devised and implemented the nr model	devised and implemented the hb model	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
4571574	26323766	R.J.B.	2	devised and implemented the hb model|devised and implemented the nr model	devised and implemented the nr model	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
4571574	26323766	S.C.	2	devised and implemented the nr model	devised and implemented the nr model	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
4571574	26323766	S.E.H.	2	conceived and performed the analyses and wrote the paper|devised and implemented the hb model|devised and implemented the nr model	conceived and performed the analyses and wrote the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
4571574	26323766	S.E.H.	2	conceived and performed the analyses and wrote the paper|devised and implemented the hb model|devised and implemented the nr model	devised and implemented the hb model	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
4571574	26323766	S.E.H.	2	conceived and performed the analyses and wrote the paper|devised and implemented the hb model|devised and implemented the nr model	devised and implemented the nr model	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
4571574	26323766	T.A.W.	2	conceived and performed the analyses and wrote the paper	conceived and performed the analyses and wrote the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
4571574	26323766	T.M.E.	2	provided guidance and contributed significant editing of the paper	provided guidance and contributed significant editing of the paper	Wrote the paper	Supervision|Writing - Review & Editing	YES
4571574	26323766	T.M.W.N.	2	devised and implemented the hb model|devised and implemented the nr model	devised and implemented the hb model	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
4571574	26323766	T.M.W.N.	2	devised and implemented the hb model|devised and implemented the nr model	devised and implemented the nr model	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
5686545	29038173	JR	PLoS52	designed the study and wrote the manuscript|provided biochemistry expertise	designed the study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5686545	29038173	JR	PLoS52	designed the study and wrote the manuscript|provided biochemistry expertise	provided biochemistry expertise	Performed the experiments	Investigation	YES
5686545	29038173	MT	PLoS52	cloned lis1 and p150-n|provided biochemistry expertise	cloned lis1 and p150-n	Performed the experiments	Investigation	YES
5686545	29038173	MT	PLoS52	cloned lis1 and p150-n|provided biochemistry expertise	provided biochemistry expertise	Performed the experiments	Investigation	YES
5686545	29038173	NIC	PLoS52	analysed data	analysed data	Analyzed the data	Formal analysis	YES
5686545	29038173	RJ	PLoS52	performed the experiments|analysed data|designed the study and wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5686545	29038173	RJ	PLoS52	performed the experiments|analysed data|designed the study and wrote the manuscript	analysed data	Analyzed the data	Formal analysis	YES
5686545	29038173	RJ	PLoS52	performed the experiments|analysed data|designed the study and wrote the manuscript	designed the study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5686545	29038173	TS	PLoS52	analysed data|designed the study and wrote the manuscript	analysed data	Analyzed the data	Formal analysis	YES
5686545	29038173	TS	PLoS52	analysed data|designed the study and wrote the manuscript	designed the study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5987390	29866199	DA	2	carried out the bulk of study activities, including recruitment, assessment, and analysis under the	carried out the bulk of study activities, including recruitment, assessment, and analysis under the	Performed the experiments	Investigation	YES
5987390	29866199	MC	2	supervised the and analysis under the	supervised the and analysis under the	-	Supervision	YES
6097079	29344744	HC	2	contributed to the migration and invasion assays and the statistical analyses	contributed to the migration and invasion assays and the statistical analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6097079	29344744	HS	2	carried out the cell culture, rt pcr, st-1 assay, and angiogenesis assay	carried out the cell culture, rt pcr, st-1 assay, and angiogenesis assay	Performed the experiments	Investigation	YES
6097079	29344744	JD	2	performed the cell culture, elisa, and the literature search	performed the cell culture, elisa, and the literature search	Performed the experiments	Formal analysis|Investigation	YES
6097079	29344744	JM	2	carried out the cell culture, rt pcr, st-1 assay, and angiogenesis assay|contributed to the drafting of the manuscript|contributed to the migration and invasion assays and the statistical analyses|designed the experiments and contributed to the writing of the manuscript|conceived the project and aided in the experimental design	carried out the cell culture, rt pcr, st-1 assay, and angiogenesis assay	Performed the experiments	Investigation	YES
6097079	29344744	JM	2	carried out the cell culture, rt pcr, st-1 assay, and angiogenesis assay|contributed to the drafting of the manuscript|contributed to the migration and invasion assays and the statistical analyses|designed the experiments and contributed to the writing of the manuscript|conceived the project and aided in the experimental design	contributed to the drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
6097079	29344744	JM	2	carried out the cell culture, rt pcr, st-1 assay, and angiogenesis assay|contributed to the drafting of the manuscript|contributed to the migration and invasion assays and the statistical analyses|designed the experiments and contributed to the writing of the manuscript|conceived the project and aided in the experimental design	contributed to the migration and invasion assays and the statistical analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6097079	29344744	JM	2	carried out the cell culture, rt pcr, st-1 assay, and angiogenesis assay|contributed to the drafting of the manuscript|contributed to the migration and invasion assays and the statistical analyses|designed the experiments and contributed to the writing of the manuscript|conceived the project and aided in the experimental design	designed the experiments and contributed to the writing of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
6097079	29344744	JM	2	carried out the cell culture, rt pcr, st-1 assay, and angiogenesis assay|contributed to the drafting of the manuscript|contributed to the migration and invasion assays and the statistical analyses|designed the experiments and contributed to the writing of the manuscript|conceived the project and aided in the experimental design	conceived the project and aided in the experimental design	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
6097079	29344744	JQ	2	carried out the cell culture, rt pcr, st-1 assay, and angiogenesis assay	carried out the cell culture, rt pcr, st-1 assay, and angiogenesis assay	Performed the experiments	Investigation	YES
6097079	29344744	QC	2	contributed to the drafting of the manuscript|designed the experiments and contributed to the writing of the manuscript	contributed to the drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
6097079	29344744	QC	2	contributed to the drafting of the manuscript|designed the experiments and contributed to the writing of the manuscript	designed the experiments and contributed to the writing of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
6097079	29344744	TG	2	carried out the cell culture, rt pcr, st-1 assay, and angiogenesis assay|designed the experiments and contributed to the writing of the manuscript	carried out the cell culture, rt pcr, st-1 assay, and angiogenesis assay	Performed the experiments	Investigation	YES
6097079	29344744	TG	2	carried out the cell culture, rt pcr, st-1 assay, and angiogenesis assay|designed the experiments and contributed to the writing of the manuscript	designed the experiments and contributed to the writing of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
6097079	29344744	XZ	2	performed the cell culture, elisa, and the literature search	performed the cell culture, elisa, and the literature search	Performed the experiments	Formal analysis|Investigation	YES
6097079	29344744	YL	2	contributed to the migration and invasion assays and the statistical analyses	contributed to the migration and invasion assays and the statistical analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6097079	29344744	ZG	2	carried out the cell culture, rt pcr, st-1 assay, and angiogenesis assay|contributed to the drafting of the manuscript|performed the cell culture, elisa, and the literature search|designed the experiments and contributed to the writing of the manuscript|conceived the project and aided in the experimental design	carried out the cell culture, rt pcr, st-1 assay, and angiogenesis assay	Performed the experiments	Investigation	YES
6097079	29344744	ZG	2	carried out the cell culture, rt pcr, st-1 assay, and angiogenesis assay|contributed to the drafting of the manuscript|performed the cell culture, elisa, and the literature search|designed the experiments and contributed to the writing of the manuscript|conceived the project and aided in the experimental design	contributed to the drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
6097079	29344744	ZG	2	carried out the cell culture, rt pcr, st-1 assay, and angiogenesis assay|contributed to the drafting of the manuscript|performed the cell culture, elisa, and the literature search|designed the experiments and contributed to the writing of the manuscript|conceived the project and aided in the experimental design	performed the cell culture, elisa, and the literature search	Performed the experiments	Formal analysis|Investigation	YES
6097079	29344744	ZG	2	carried out the cell culture, rt pcr, st-1 assay, and angiogenesis assay|contributed to the drafting of the manuscript|performed the cell culture, elisa, and the literature search|designed the experiments and contributed to the writing of the manuscript|conceived the project and aided in the experimental design	designed the experiments and contributed to the writing of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
6097079	29344744	ZG	2	carried out the cell culture, rt pcr, st-1 assay, and angiogenesis assay|contributed to the drafting of the manuscript|performed the cell culture, elisa, and the literature search|designed the experiments and contributed to the writing of the manuscript|conceived the project and aided in the experimental design	conceived the project and aided in the experimental design	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
1950564	17786190	AP	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1950564	17786190	GM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1950564	17786190	OM	PLoS5	Supervised the work	Supervised the work	-	Supervision	YES
1950564	17786190	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1950564	17786190	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1950564	17786190	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1950564	17786190	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1950564	17786190	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1950564	17786190	YB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5787101	29410672	CQ	7	performed research	performed research	Performed the experiments	Investigation	YES
5787101	29410672	GW	7	performed research	performed research	Performed the experiments	Investigation	YES
5787101	29410672	JW	7	performed research|analyzed the data|wrote the paper	performed research	Performed the experiments	Investigation	YES
5787101	29410672	JW	7	performed research|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5787101	29410672	JW	7	performed research|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5787101	29410672	LZ	7	designed research|performed research|analyzed the data|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
5787101	29410672	LZ	7	designed research|performed research|analyzed the data|wrote the paper	performed research	Performed the experiments	Investigation	YES
5787101	29410672	LZ	7	designed research|performed research|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5787101	29410672	LZ	7	designed research|performed research|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5787101	29410672	ML	7	performed research	performed research	Performed the experiments	Investigation	YES
5787101	29410672	X-XW	7	designed research|performed research|analyzed the data|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
5787101	29410672	X-XW	7	designed research|performed research|analyzed the data|wrote the paper	performed research	Performed the experiments	Investigation	YES
5787101	29410672	X-XW	7	designed research|performed research|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5787101	29410672	X-XW	7	designed research|performed research|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5787101	29410672	XL	7	performed research	performed research	Performed the experiments	Investigation	YES
5787101	29410672	XW	7	performed research	performed research	Performed the experiments	Investigation	YES
5787101	29410672	Y-DG	7	designed research|analyzed the data|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
5787101	29410672	Y-DG	7	designed research|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5787101	29410672	Y-DG	7	designed research|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416706	25933429	AK	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416706	25933429	AK	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416706	25933429	AK	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416706	25933429	AK	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416706	25933429	AO	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416706	25933429	AO	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416706	25933429	AO	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416706	25933429	AO	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416706	25933429	AT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416706	25933429	AT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416706	25933429	AT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416706	25933429	AT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416706	25933429	AT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416706	25933429	CJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416706	25933429	CJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416706	25933429	CJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416706	25933429	CJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416706	25933429	CJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416706	25933429	CT	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416706	25933429	CT	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416706	25933429	CT	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416706	25933429	CT	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416706	25933429	DC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416706	25933429	DC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416706	25933429	DC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416706	25933429	EBI	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416706	25933429	EBI	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416706	25933429	EBI	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416706	25933429	JW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416706	25933429	JW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416706	25933429	JW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416706	25933429	KPA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Overall project coordinator	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416706	25933429	KPA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Overall project coordinator	Performed the experiments	Performed the experiments	Investigation	YES
4416706	25933429	KPA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Overall project coordinator	Analyzed the data	Analyzed the data	Formal analysis	YES
4416706	25933429	KPA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Overall project coordinator	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416706	25933429	KPA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Overall project coordinator	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416706	25933429	KPA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Overall project coordinator	Overall project coordinator	-	Project administration	YES
4416706	25933429	LGF	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416706	25933429	LGF	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416706	25933429	LGF	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416706	25933429	LGF	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416706	25933429	SBS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416706	25933429	SBS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416706	25933429	SBS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416706	25933429	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416706	25933429	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416706	25933429	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416706	25933429	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416706	25933429	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416706	25933429	SOA	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416706	25933429	SOA	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416706	25933429	SOA	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416706	25933429	VA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416706	25933429	VA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416706	25933429	VA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416706	25933429	VA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416706	25933429	VA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5474227	28629206	AEG	2	performed the research study|drafted the manuscript	performed the research study	Performed the experiments	Investigation	YES
5474227	28629206	AEG	2	performed the research study|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5474227	28629206	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5474227	28629206	CZ	2	performed the research study	performed the research study	Performed the experiments	Investigation	YES
5474227	28629206	LS	2	performed the research study	performed the research study	Performed the experiments	Investigation	YES
5474227	28629206	ML	2	designed the work	designed the work	Conceived and designed the experiments	-	YES
5474227	28629206	SJ	2	zd analysis the data	zd analysis the data	Analyzed the data	Formal analysis	YES
5474227	28629206	WL	2	were involved in critically revision the manuscript	were involved in critically revision the manuscript	Wrote the paper	Writing - Review & Editing	YES
5474227	28629206	YY	2	designed the work|were involved in critically revision the manuscript	designed the work	Conceived and designed the experiments	-	YES
5474227	28629206	YY	2	designed the work|were involved in critically revision the manuscript	were involved in critically revision the manuscript	Wrote the paper	Writing - Review & Editing	YES
5474227	28629206	YZ	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5474227	28629206	ZY	2	performed the research study	performed the research study	Performed the experiments	Investigation	YES
6001005	29898738	DM	2	undertook data interpretation and manuscript preparation	undertook data interpretation and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6001005	29898738	IB	2	undertook data interpretation and manuscript preparation	undertook data interpretation and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6001005	29898738	M-CR	2	undertook data interpretation and manuscript preparation	undertook data interpretation and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6001005	29898738	MM	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
6001005	29898738	MP-Q	2	undertook data interpretation and manuscript preparation	undertook data interpretation and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5715535	29202695	CW	2	carried out experiments	carried out experiments	Performed the experiments	Investigation	YES
5715535	29202695	GX	2	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5715535	29202695	JY	2	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5715535	29202695	KH	2	carried out experiments	carried out experiments	Performed the experiments	Investigation	YES
5715535	29202695	LW	2	carried out experiments	carried out experiments	Performed the experiments	Investigation	YES
5715535	29202695	NW	2	carried out experiments	carried out experiments	Performed the experiments	Investigation	YES
5715535	29202695	QL	2	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5715535	29202695	XC	2	carried out experiments	carried out experiments	Performed the experiments	Investigation	YES
5715535	29202695	XS	2	carried out experiments|analyzed data|interpreted the data and drafted the manuscript	carried out experiments	Performed the experiments	Investigation	YES
5715535	29202695	XS	2	carried out experiments|analyzed data|interpreted the data and drafted the manuscript	analyzed data	Analyzed the data	Formal analysis	YES
5715535	29202695	XS	2	carried out experiments|analyzed data|interpreted the data and drafted the manuscript	interpreted the data and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5715535	29202695	XZ	2	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5715535	29202695	YQ	2	carried out experiments	carried out experiments	Performed the experiments	Investigation	YES
5715535	29202695	YS	2	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5715535	29202695	ZH	2	conceived and designed the study|interpreted the data and drafted the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5715535	29202695	ZH	2	conceived and designed the study|interpreted the data and drafted the manuscript	interpreted the data and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5715535	29202695	ZL	2	carried out experiments	carried out experiments	Performed the experiments	Investigation	YES
4581024	26056363	All authors	2	contributed to the conception, literature review and writing of this manuscript	contributed to the conception, literature review and writing of this manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
4628758	26557675	Sayeed Ahmad	2	made equal contribution	made equal contribution	-	-	NO
4628758	26557675	Syed Akhtar Husain	2	made equal contribution	made equal contribution	-	-	NO
5686552	28963396	AB-B	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5686552	28963396	AWa	PLoS52	designed the work	designed the work	Conceived and designed the experiments	-	YES
5686552	28963396	AWl	PLoS52	designed the work|performed the experiments|analyzed the data|wrote the manuscript	designed the work	Conceived and designed the experiments	-	YES
5686552	28963396	AWl	PLoS52	designed the work|performed the experiments|analyzed the data|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5686552	28963396	AWl	PLoS52	designed the work|performed the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5686552	28963396	AWl	PLoS52	designed the work|performed the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5686552	28963396	BJLE	PLoS52	designed the work|analyzed the data	designed the work	Conceived and designed the experiments	-	YES
5686552	28963396	BJLE	PLoS52	designed the work|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5686552	28963396	EWGMB	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5686552	28963396	IK	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5686552	28963396	IRH	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5686552	28963396	JB	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5686552	28963396	JB	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5686552	28963396	JJB-B	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5686552	28963396	KK	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5686552	28963396	MK	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5686552	28963396	MK	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5686552	28963396	NAM	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5686552	28963396	NY	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5686552	28963396	RK	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5686552	28963396	TO	PLoS52	designed the work|wrote the manuscript	designed the work	Conceived and designed the experiments	-	YES
5686552	28963396	TO	PLoS52	designed the work|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5787103	29410673	AP	7	wrote the manuscript|analyzed the data	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5787103	29410673	AP	7	wrote the manuscript|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5787103	29410673	EF	7	wrote the manuscript|developed methods and conducted the experiments|analyzed the data|secured the funding	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5787103	29410673	EF	7	wrote the manuscript|developed methods and conducted the experiments|analyzed the data|secured the funding	developed methods and conducted the experiments	Performed the experiments	Investigation|Methodology	YES
5787103	29410673	EF	7	wrote the manuscript|developed methods and conducted the experiments|analyzed the data|secured the funding	analyzed the data	Analyzed the data	Formal analysis	YES
5787103	29410673	EF	7	wrote the manuscript|developed methods and conducted the experiments|analyzed the data|secured the funding	secured the funding	-	Funding acquisition	YES
5787103	29410673	MJ	7	wrote the manuscript|developed methods and conducted the experiments|analyzed the data	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5787103	29410673	MJ	7	wrote the manuscript|developed methods and conducted the experiments|analyzed the data	developed methods and conducted the experiments	Performed the experiments	Investigation|Methodology	YES
5787103	29410673	MJ	7	wrote the manuscript|developed methods and conducted the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5787103	29410673	PO	7	wrote the manuscript|secured the funding	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5787103	29410673	PO	7	wrote the manuscript|secured the funding	secured the funding	-	Funding acquisition	YES
1950565	17786191	AK	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1950565	17786191	BG	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1950565	17786191	BM	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1950565	17786191	CF	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1950565	17786191	CG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1950565	17786191	HT	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1950565	17786191	HT	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1950565	17786191	JD	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1950565	17786191	JE	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1950565	17786191	JE	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1950565	17786191	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1950565	17786191	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1950565	17786191	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1950565	17786191	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1950565	17786191	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1950565	17786191	JS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1950565	17786191	JS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1950565	17786191	JS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1950565	17786191	JS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1950565	17786191	KM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1950565	17786191	LT	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1950565	17786191	MF	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1950565	17786191	MW	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1950565	17786191	MW	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1950565	17786191	PL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1950565	17786191	PL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1950565	17786191	PL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1950565	17786191	SB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Organized collaboration between the different institutions	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1950565	17786191	SB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Organized collaboration between the different institutions	Analyzed the data	Analyzed the data	Formal analysis	YES
1950565	17786191	SB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Organized collaboration between the different institutions	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1950565	17786191	SB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Organized collaboration between the different institutions	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1950565	17786191	SB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Organized collaboration between the different institutions	Organized collaboration between the different institutions	-	-	NO
1950565	17786191	SP	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1950565	17786191	SS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1950565	17786191	TG	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1950565	17786191	TM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1950565	17786191	TO	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1950565	17786191	US	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1950565	17786191	WK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1950565	17786191	WK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416707	25933162	AP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416707	25933162	AP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416707	25933162	AP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416707	25933162	AP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416707	25933162	AP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416707	25933162	BDZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416707	25933162	BDZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416707	25933162	BDZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416707	25933162	BDZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416707	25933162	BDZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416707	25933162	KKE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416707	25933162	KKE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416707	25933162	KKE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416707	25933162	KKE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416707	25933162	KKE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5474230	28629207	AMV	2	designed and performed experiments, interpreted results, and wrote the manuscript	designed and performed experiments, interpreted results, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5474230	28629207	AV	2	stored at utrecht university library database	stored at utrecht university library database	Contributed reagents/materials/analysis tools	Software	YES
5474230	28629207	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5474230	28629207	EH	2	designed and performed experiments and interpreted results	designed and performed experiments and interpreted results	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5474230	28629207	EJ	2	designed and performed experiments, interpreted results, and wrote the manuscript	designed and performed experiments, interpreted results, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5474230	28629207	GP	2	designed and performed experiments and interpreted results	designed and performed experiments and interpreted results	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5474230	28629207	HABW	2	interpreted results and wrote the manuscript	interpreted results and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5474230	28629207	JFP	2	designed and performed experiments and interpreted results	designed and performed experiments and interpreted results	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5474230	28629207	JJB	2	designed experiments and interpreted results	designed experiments and interpreted results	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5474230	28629207	KH	2	designed and performed experiments and interpreted results	designed and performed experiments and interpreted results	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5474230	28629207	LGL	2	designed experiments and interpreted results	designed experiments and interpreted results	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5474230	28629207	MAK	2	designed experiments and interpreted results	designed experiments and interpreted results	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5474230	28629207	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5715654	29202697	AS	PLoS52	carried out phenotyping and genotyping|analyzed the data|composed the draft of the manuscript|directed and managed this research	carried out phenotyping and genotyping	Performed the experiments	Investigation	YES
5715654	29202697	AS	PLoS52	carried out phenotyping and genotyping|analyzed the data|composed the draft of the manuscript|directed and managed this research	analyzed the data	Analyzed the data	Formal analysis	YES
5715654	29202697	AS	PLoS52	carried out phenotyping and genotyping|analyzed the data|composed the draft of the manuscript|directed and managed this research	composed the draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
5715654	29202697	AS	PLoS52	carried out phenotyping and genotyping|analyzed the data|composed the draft of the manuscript|directed and managed this research	directed and managed this research	-	Supervision	YES
5715654	29202697	All authors	PLoS52	have read, made corrections and approved the final manuscript	have read, made corrections and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5715654	29202697	BM	PLoS52	carried out phenotyping and genotyping|reviewed and edited the manuscript	carried out phenotyping and genotyping	Performed the experiments	Investigation	YES
5715654	29202697	BM	PLoS52	carried out phenotyping and genotyping|reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5715654	29202697	GB	PLoS52	carried out phenotyping and genotyping	carried out phenotyping and genotyping	Performed the experiments	Investigation	YES
5715654	29202697	JQ	PLoS52	carried out phenotyping and genotyping|analyzed the data|composed the draft of the manuscript	carried out phenotyping and genotyping	Performed the experiments	Investigation	YES
5715654	29202697	JQ	PLoS52	carried out phenotyping and genotyping|analyzed the data|composed the draft of the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5715654	29202697	JQ	PLoS52	carried out phenotyping and genotyping|analyzed the data|composed the draft of the manuscript	composed the draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
5715654	29202697	LD	PLoS52	carried out phenotyping and genotyping	carried out phenotyping and genotyping	Performed the experiments	Investigation	YES
5715654	29202697	MG	PLoS52	carried out phenotyping and genotyping|directed and managed this research|reviewed and edited the manuscript	carried out phenotyping and genotyping	Performed the experiments	Investigation	YES
5715654	29202697	MG	PLoS52	carried out phenotyping and genotyping|directed and managed this research|reviewed and edited the manuscript	directed and managed this research	-	Supervision	YES
5715654	29202697	MG	PLoS52	carried out phenotyping and genotyping|directed and managed this research|reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5715654	29202697	WR	PLoS52	carried out phenotyping and genotyping	carried out phenotyping and genotyping	Performed the experiments	Investigation	YES
5715654	29202697	WY	PLoS52	carried out phenotyping and genotyping	carried out phenotyping and genotyping	Performed the experiments	Investigation	YES
5715654	29202697	YW	PLoS52	carried out phenotyping and genotyping	carried out phenotyping and genotyping	Performed the experiments	Investigation	YES
4581025	26056364	A.M.B.	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4581025	26056364	All authors	2	have given final approval for the manuscript	have given final approval for the manuscript	-	-	NO
4581025	26056364	All of the authors	2	contributed to the conception of the paper as well as the discovery and interpretation of relevant literature	contributed to the conception of the paper as well as the discovery and interpretation of relevant literature	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
4581025	26056364	C.A.A.	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4581025	26056364	F.B.	2	revised the manuscript for intellectual content	revised the manuscript for intellectual content	Wrote the paper	Writing - Review & Editing	YES
4581025	26056364	G.S.W.	2	revised the manuscript for intellectual content	revised the manuscript for intellectual content	Wrote the paper	Writing - Review & Editing	YES
4581025	26056364	H.K.	2	developed and ran the model|drafted the manuscript	developed and ran the model	Performed the experiments	Investigation|Methodology	YES
4581025	26056364	H.K.	2	developed and ran the model|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
1950566	17786193	LN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1950566	17786193	LN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1950566	17786193	LN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1950566	17786193	LN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1950566	17786193	PA	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
6006686	29914522	KI	2	designed the study|interpreted results, edited, revised and approved the final version of the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
6006686	29914522	KI	2	designed the study|interpreted results, edited, revised and approved the final version of the manuscript	interpreted results, edited, revised and approved the final version of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
6006686	29914522	MCM	2	performed experiments, analyzed data, prepared figures and drafted the manuscript|designed the study|interpreted results, edited, revised and approved the final version of the manuscript	performed experiments, analyzed data, prepared figures and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Visualization|Writing - Original Draft	YES
6006686	29914522	MCM	2	performed experiments, analyzed data, prepared figures and drafted the manuscript|designed the study|interpreted results, edited, revised and approved the final version of the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
6006686	29914522	MCM	2	performed experiments, analyzed data, prepared figures and drafted the manuscript|designed the study|interpreted results, edited, revised and approved the final version of the manuscript	interpreted results, edited, revised and approved the final version of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
6006686	29914522	SM	2	interpreted results, edited, revised and approved the final version of the manuscript	interpreted results, edited, revised and approved the final version of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5787578	29416546	JC	2	collected and processed public data	collected and processed public data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5787578	29416546	JL	2	constructed the web server	constructed the web server	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5787578	29416546	MQ	2	collected and processed public data	collected and processed public data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5787578	29416546	XR	2	constructed the web server|collected and processed public data|wrote the manuscript	constructed the web server	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5787578	29416546	XR	2	constructed the web server|collected and processed public data|wrote the manuscript	collected and processed public data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5787578	29416546	XR	2	constructed the web server|collected and processed public data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5787578	29416546	YW	2	collected and processed public data	collected and processed public data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5787578	29416546	YZ	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4416709	25933397	JW	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416709	25933397	JW	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416709	25933397	MJ	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416709	25933397	MJ	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416709	25933397	MR	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416709	25933397	MTR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416709	25933397	MTR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416709	25933397	MTR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416709	25933397	RM	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416709	25933397	RM	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5476557	28633512	AKK	2	participated in its design and coordination, interpreted the data, and helped to draft the manuscript	participated in its design and coordination, interpreted the data, and helped to draft the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Project administration|Writing - Original Draft	YES
5476557	28633512	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5476557	28633512	JK	2	performed the experiments and the data analysis	performed the experiments and the data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5476557	28633512	JW	2	performed the experiments and the data analysis	performed the experiments and the data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5476557	28633512	MP	2	conceived of the study, participated in its design and coordination, performed the experiments, interpreted the data, and drafted the manuscript	conceived of the study, participated in its design and coordination, performed the experiments, interpreted the data, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Project administration|Writing - Original Draft	YES
5476557	28633512	PJ	2	participated in its design and coordination, interpreted the data and helped to draft the manuscript	participated in its design and coordination, interpreted the data and helped to draft the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Project administration|Writing - Original Draft	YES
5476557	28633512	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5476557	28633512	ZT	2	conceived of the study, participated in its design and coordination, and helped to draft the manuscript	conceived of the study, participated in its design and coordination, and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
1950567	17786194	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1950567	17786194	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1950567	17786194	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1950567	17786194	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1950567	17786194	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1950567	17786194	BV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1950567	17786194	BV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1950567	17786194	BV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1950567	17786194	CS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1950567	17786194	CS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1950567	17786194	CS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1950567	17786194	CS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1950567	17786194	CS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1950567	17786194	HT	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1950567	17786194	HT	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1950567	17786194	JC	PLoS5	Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1950567	17786194	JC	PLoS5	Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1950567	17786194	JC	PLoS5	Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1950567	17786194	JC	PLoS5	Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1950567	17786194	JF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1950567	17786194	JF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1950567	17786194	JF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1950567	17786194	JF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1950567	17786194	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1950567	17786194	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1950567	17786194	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1950567	17786194	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1950567	17786194	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1950567	17786194	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1950567	17786194	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1950567	17786194	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1950567	17786194	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1950567	17786194	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1950567	17786194	LD	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1950567	17786194	LD	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1950567	17786194	LH	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1950567	17786194	LH	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1950567	17786194	LQ	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1950567	17786194	LQ	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1950567	17786194	LT	PLoS5	Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1950567	17786194	LT	PLoS5	Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1950567	17786194	LT	PLoS5	Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1950567	17786194	LT	PLoS5	Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1950567	17786194	LV	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1950567	17786194	LV	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1950567	17786194	LV	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1950567	17786194	LV	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1950567	17786194	LV	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1950567	17786194	LV	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1950567	17786194	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1950567	17786194	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1950567	17786194	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1950567	17786194	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1950567	17786194	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1950567	17786194	ND	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1950567	17786194	ND	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1950567	17786194	ND	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1950567	17786194	NK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1950567	17786194	NK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1950567	17786194	NK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1950567	17786194	NM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1950567	17786194	NM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1950567	17786194	NM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1950567	17786194	NT	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1950567	17786194	NT	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1950567	17786194	NT	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1950567	17786194	NT	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1950567	17786194	NT	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1950567	17786194	NT	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1950567	17786194	NT	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1950567	17786194	NT	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1950567	17786194	NT	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1950567	17786194	NT	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1950567	17786194	NV	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1950567	17786194	NV	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1950567	17786194	PV	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1950567	17786194	PV	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1950567	17786194	RB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1950567	17786194	RB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1950567	17786194	RB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1950567	17786194	RB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1950567	17786194	RB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1950567	17786194	TC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1950567	17786194	TC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1950567	17786194	TC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1950567	17786194	TS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1950567	17786194	TS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1950567	17786194	TT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1950567	17786194	TT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1950567	17786194	TT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5787579	29416547	GN	7	Contributed to revising manuscript	Contributed to revising manuscript	Wrote the paper	Writing - Review & Editing	YES
5787579	29416547	HM	7	Contributed to revising manuscript	Contributed to revising manuscript	Wrote the paper	Writing - Review & Editing	YES
5787579	29416547	JG	7	Conducted the experiments, analyzed the experimental data, and wrote the manuscript|Designed the experiment	Conducted the experiments, analyzed the experimental data, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5787579	29416547	JG	7	Conducted the experiments, analyzed the experimental data, and wrote the manuscript|Designed the experiment	Designed the experiment	Conceived and designed the experiments	Methodology	YES
5787579	29416547	LO	7	Contributed to revising manuscript	Contributed to revising manuscript	Wrote the paper	Writing - Review & Editing	YES
5787579	29416547	LZ	7	Contributed to revising manuscript	Contributed to revising manuscript	Wrote the paper	Writing - Review & Editing	YES
5787579	29416547	PZ	7	Designed the experiment|Contributed to revising manuscript	Designed the experiment	Conceived and designed the experiments	Methodology	YES
5787579	29416547	PZ	7	Designed the experiment|Contributed to revising manuscript	Contributed to revising manuscript	Wrote the paper	Writing - Review & Editing	YES
5787579	29416547	XC	7	Conducted the experiments, analyzed the experimental data, and wrote the manuscript	Conducted the experiments, analyzed the experimental data, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4628761	26557666	Chen-Jei Tai	2	contributed equally to this study	contributed equally to this study	-	-	NO
4628761	26557666	Liang-Tzung Lin	2	contributed equally to this study	contributed equally to this study	-	-	NO
6020314	29945625	CK	2	were involved in testing and laboratory analyses	were involved in testing and laboratory analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6020314	29945625	DSW	2	was the principal investigator and was responsible for securing grant funding and developing the experimental design|was also involved in training and mentoring graduate student personnel for laboratory analyses, provided primary oversight during the course of the study, and performed the majority of manuscript preparation	was the principal investigator and was responsible for securing grant funding and developing the experimental design	Conceived and designed the experiments|Performed the experiments	Conceptualization|Funding acquisition|Investigation|Methodology	YES
6020314	29945625	DSW	2	was the principal investigator and was responsible for securing grant funding and developing the experimental design|was also involved in training and mentoring graduate student personnel for laboratory analyses, provided primary oversight during the course of the study, and performed the majority of manuscript preparation	was also involved in training and mentoring graduate student personnel for laboratory analyses, provided primary oversight during the course of the study, and performed the majority of manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Supervision|Writing - Original Draft	YES
6020314	29945625	FM	2	performed dietary analyses	performed dietary analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6020314	29945625	JG	2	were involved in testing and laboratory analyses	were involved in testing and laboratory analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6020314	29945625	MM	2	was involved in assisting with developing experimental design, performing statistical analyses, and manuscript preparation	was involved in assisting with developing experimental design, performing statistical analyses, and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
6020314	29945625	PW	2	served as the study coordinator and was involved in participant recruitment, testing, laboratory analyses, and assisted in manuscript preparation	served as the study coordinator and was involved in participant recruitment, testing, laboratory analyses, and assisted in manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Project administration|Writing - Original Draft	YES
6020314	29945625	SMB	2	were involved in testing and laboratory analyses	were involved in testing and laboratory analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6020314	29945625	TA	2	were involved in testing and laboratory analyses	were involved in testing and laboratory analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4581027	26056366	All authors	2	contributed to the preparation of this manuscript and approved the final version	contributed to the preparation of this manuscript and approved the final version	Wrote the paper	Writing - Original Draft	YES
4581027	26056366	C.M.	2	designed and directed this work	designed and directed this work	Conceived and designed the experiments	Supervision	YES
4581027	26056366	L.W.	2	designed and directed this work|on the blast analysis	designed and directed this work	Conceived and designed the experiments	Supervision	YES
4581027	26056366	L.W.	2	designed and directed this work|on the blast analysis	on the blast analysis	-	-	NO
4581027	26056366	T.G.	2	wrote the code for the wright-fisher model and all authors provided interpretation of results presented	wrote the code for the wright-fisher model and all authors provided interpretation of results presented	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Software|Writing - Original Draft	YES
5715996	29202712	ATN	2	performed the rna seq	performed the rna seq	Performed the experiments	Investigation	YES
5715996	29202712	DH	2	coordinated the study and wrote the manuscript	coordinated the study and wrote the manuscript	Wrote the paper	Project administration|Writing - Original Draft	YES
5715996	29202712	HT	2	initiated and supervised the project, carried out all data analyses, and wrote the manuscript	initiated and supervised the project, carried out all data analyses, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Supervision|Writing - Original Draft	YES
5715996	29202712	SK	2	coordinated the study	coordinated the study	-	Project administration	YES
5715996	29202712	TG	2	coordinated the study	coordinated the study	-	Project administration	YES
5715996	29202712	YK	2	conceived the study, participated in designing and coordinating the study, carried out the rna seq, and wrote the manuscript	conceived the study, participated in designing and coordinating the study, carried out the rna seq, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Project administration|Writing - Original Draft	YES
5479772	28641404	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5479772	28641404	HY	PLoS52	designed the experiments and revised the paper	designed the experiments and revised the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5479772	28641404	Ningbo Municipal Science	PLoS52	technology bureau	technology bureau	-	-	NO
5479772	28641404	RX	PLoS52	performed the experiments and wrote the paper|analyzed the data	performed the experiments and wrote the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5479772	28641404	RX	PLoS52	performed the experiments and wrote the paper|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5479772	28641404	SH	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5479772	28641404	The authors	PLoS52	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5479772	28641404	X-EL	PLoS52	designed the experiments and revised the paper|analyzed the data	designed the experiments and revised the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5479772	28641404	X-EL	PLoS52	designed the experiments and revised the paper|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5694950	28043948	HH	2	designed the experiments|performed the experiments and/or provided advice and technical expertise|carried out organoid culture analysis|wrote the manuscript, and all authors amended the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5694950	28043948	HH	2	designed the experiments|performed the experiments and/or provided advice and technical expertise|carried out organoid culture analysis|wrote the manuscript, and all authors amended the manuscript	performed the experiments and/or provided advice and technical expertise	Performed the experiments	Investigation	YES
5694950	28043948	HH	2	designed the experiments|performed the experiments and/or provided advice and technical expertise|carried out organoid culture analysis|wrote the manuscript, and all authors amended the manuscript	carried out organoid culture analysis	Performed the experiments	Investigation	YES
5694950	28043948	HH	2	designed the experiments|performed the experiments and/or provided advice and technical expertise|carried out organoid culture analysis|wrote the manuscript, and all authors amended the manuscript	wrote the manuscript, and all authors amended the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5694950	28043948	JM	2	performed the experiments and/or provided advice and technical expertise	performed the experiments and/or provided advice and technical expertise	Performed the experiments	Investigation	YES
5694950	28043948	KK	2	carried out organoid culture analysis	carried out organoid culture analysis	Performed the experiments	Investigation	YES
5694950	28043948	KT	2	provided unique reagents	provided unique reagents	Contributed reagents/materials/analysis tools	Resources	YES
5694950	28043948	ME	2	designed the experiments|performed the experiments and/or provided advice and technical expertise|wrote the manuscript, and all authors amended the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5694950	28043948	ME	2	designed the experiments|performed the experiments and/or provided advice and technical expertise|wrote the manuscript, and all authors amended the manuscript	performed the experiments and/or provided advice and technical expertise	Performed the experiments	Investigation	YES
5694950	28043948	ME	2	designed the experiments|performed the experiments and/or provided advice and technical expertise|wrote the manuscript, and all authors amended the manuscript	wrote the manuscript, and all authors amended the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5694950	28043948	TK	2	performed the experiments and/or provided advice and technical expertise	performed the experiments and/or provided advice and technical expertise	Performed the experiments	Investigation	YES
5694950	28043948	YO	2	designed the experiments|wrote the manuscript, and all authors amended the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5694950	28043948	YO	2	designed the experiments|wrote the manuscript, and all authors amended the manuscript	wrote the manuscript, and all authors amended the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4416710	25932629	JY	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416710	25932629	JY	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416710	25932629	KD	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416710	25932629	MT	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416710	25932629	S. Yamawaki	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416710	25932629	S. Yoshimura	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416710	25932629	ST	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416710	25932629	ST	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416710	25932629	YO	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416710	25932629	YS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416710	25932629	YS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416710	25932629	YS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1950568	17726542	EL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1950568	17726542	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1950568	17726542	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1950568	17726542	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1950568	17726542	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1950568	17726542	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1950568	17726542	NA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1950568	17726542	NA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1950568	17726542	NA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1950568	17726542	PL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1950568	17726542	PS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1950568	17726542	SG	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1950568	17726542	TS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5788000	29416545	The authors	2	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	Performed the experiments	Investigation	YES
5716007	29202707	All authors	2	have been involved in drafting and revision of the manuscript, have given final approval of the version to be published, and agree to be accountable for all of their contributions to the work	have been involved in drafting and revision of the manuscript, have given final approval of the version to be published, and agree to be accountable for all of their contributions to the work	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5716007	29202707	DM	2	initial concept design, clinical studies supervision, cohort collection concept and supervision	initial concept design, clinical studies supervision, cohort collection concept and supervision	Conceived and designed the experiments	Conceptualization|Methodology|Supervision	YES
5716007	29202707	KS	2	conception, design and writing on the fsnpd programs and exome base coverage analysis program	conception, design and writing on the fsnpd programs and exome base coverage analysis program	Conceived and designed the experiments|Wrote the paper	Conceptualization	YES
5716007	29202707	ML	2	design, ethic, patient involvement, ascertainment and clinical phenotyping of test cohorts	design, ethic, patient involvement, ascertainment and clinical phenotyping of test cohorts	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5716007	29202707	NS	2	design and acquisition of experimental molecular genetic data	design and acquisition of experimental molecular genetic data	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5716007	29202707	PM	2	redesign and substantial modification of the fsnpd program, after analysis of the initial results and the user interface	redesign and substantial modification of the fsnpd program, after analysis of the initial results and the user interface	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Software	YES
6038311	29986720	DAB	PLoS52	assisted in analysis, and manuscript review|wrote the paper	assisted in analysis, and manuscript review	Wrote the paper	Writing - Review & Editing	YES
6038311	29986720	DAB	PLoS52	assisted in analysis, and manuscript review|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6038311	29986720	IG	PLoS52	conceived and designed the experiments|designed the nutritional protocols	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6038311	29986720	IG	PLoS52	conceived and designed the experiments|designed the nutritional protocols	designed the nutritional protocols	Conceived and designed the experiments	Methodology	YES
6038311	29986720	JBP	PLoS52	served as lab coordinator and project manager for the study coordination|assisted in data collection|assisted in analysis, and manuscript review|wrote the paper	served as lab coordinator and project manager for the study coordination	-	Project administration	YES
6038311	29986720	JBP	PLoS52	served as lab coordinator and project manager for the study coordination|assisted in data collection|assisted in analysis, and manuscript review|wrote the paper	assisted in data collection	Performed the experiments	Investigation	YES
6038311	29986720	JBP	PLoS52	served as lab coordinator and project manager for the study coordination|assisted in data collection|assisted in analysis, and manuscript review|wrote the paper	assisted in analysis, and manuscript review	Wrote the paper	Writing - Review & Editing	YES
6038311	29986720	JBP	PLoS52	served as lab coordinator and project manager for the study coordination|assisted in data collection|assisted in analysis, and manuscript review|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6038311	29986720	JLP	PLoS52	analyzed the data|assisted in analysis, and manuscript review|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
6038311	29986720	JLP	PLoS52	analyzed the data|assisted in analysis, and manuscript review|wrote the paper	assisted in analysis, and manuscript review	Wrote the paper	Writing - Review & Editing	YES
6038311	29986720	JLP	PLoS52	analyzed the data|assisted in analysis, and manuscript review|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6038311	29986720	RBK	PLoS52	analyzed the data|assisted in analysis, and manuscript review|assisted in the statistics advice, discussion analysis, and manuscript preparation	analyzed the data	Analyzed the data	Formal analysis	YES
6038311	29986720	RBK	PLoS52	analyzed the data|assisted in analysis, and manuscript review|assisted in the statistics advice, discussion analysis, and manuscript preparation	assisted in analysis, and manuscript review	Wrote the paper	Writing - Review & Editing	YES
6038311	29986720	RBK	PLoS52	analyzed the data|assisted in analysis, and manuscript review|assisted in the statistics advice, discussion analysis, and manuscript preparation	assisted in the statistics advice, discussion analysis, and manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6038311	29986720	RR	PLoS52	served as lab coordinator and project manager for the study coordination|assisted in data collection	served as lab coordinator and project manager for the study coordination	-	Project administration	YES
6038311	29986720	RR	PLoS52	served as lab coordinator and project manager for the study coordination|assisted in data collection	assisted in data collection	Performed the experiments	Investigation	YES
6038311	29986720	SE	PLoS52	designed the nutritional protocols	designed the nutritional protocols	Conceived and designed the experiments	Methodology	YES
6038311	29986720	SV	PLoS52	served as study coordinator|conceived and designed the experiments|assisted in data collection|designed the nutritional protocols|oversight nutrition and training|wrote the paper	served as study coordinator	-	Project administration	YES
6038311	29986720	SV	PLoS52	served as study coordinator|conceived and designed the experiments|assisted in data collection|designed the nutritional protocols|oversight nutrition and training|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6038311	29986720	SV	PLoS52	served as study coordinator|conceived and designed the experiments|assisted in data collection|designed the nutritional protocols|oversight nutrition and training|wrote the paper	assisted in data collection	Performed the experiments	Investigation	YES
6038311	29986720	SV	PLoS52	served as study coordinator|conceived and designed the experiments|assisted in data collection|designed the nutritional protocols|oversight nutrition and training|wrote the paper	designed the nutritional protocols	Conceived and designed the experiments	Methodology	YES
6038311	29986720	SV	PLoS52	served as study coordinator|conceived and designed the experiments|assisted in data collection|designed the nutritional protocols|oversight nutrition and training|wrote the paper	oversight nutrition and training	-	Supervision	YES
6038311	29986720	SV	PLoS52	served as study coordinator|conceived and designed the experiments|assisted in data collection|designed the nutritional protocols|oversight nutrition and training|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6154123	29845477	PK	2	analysis, data interpretation and writing of the manuscript, and final approval of the manuscript	analysis, data interpretation and writing of the manuscript, and final approval of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4416711	25933120	DD	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416711	25933120	GU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416711	25933120	GU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416711	25933120	GU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416711	25933120	GU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416711	25933120	HC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416711	25933120	HMA	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416711	25933120	HMA	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416711	25933120	HMA	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416711	25933120	LMM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416711	25933120	LMM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416711	25933120	LMM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416711	25933120	LMM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416711	25933120	PC	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416711	25933120	QR	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5709735	29118001	CD	2	conceived and designed the study and wrote the manuscript	conceived and designed the study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
5709735	29118001	CHH	2	conceived and designed the study and wrote the manuscript	conceived and designed the study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
5709735	29118001	JME	2	magnetic tweezer experiments and data analysis|jk software|conceived and designed the study and wrote the manuscript	magnetic tweezer experiments and data analysis	Analyzed the data	Formal analysis	YES
5709735	29118001	JME	2	magnetic tweezer experiments and data analysis|jk software|conceived and designed the study and wrote the manuscript	jk software	Contributed reagents/materials/analysis tools	Software	YES
5709735	29118001	JME	2	magnetic tweezer experiments and data analysis|jk software|conceived and designed the study and wrote the manuscript	conceived and designed the study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
5709735	29118001	MK	2	protein expression and purification	protein expression and purification	Performed the experiments	Investigation	YES
5709735	29118001	SB	2	protein expression and purification|conceived and designed the study and wrote the manuscript	protein expression and purification	Performed the experiments	Investigation	YES
5709735	29118001	SB	2	protein expression and purification|conceived and designed the study and wrote the manuscript	conceived and designed the study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
5479773	28641405	AK	2	participated in design and coordination	participated in design and coordination	Conceived and designed the experiments	Project administration	YES
5479773	28641405	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5479773	28641405	CO	2	participated in design and coordination	participated in design and coordination	Conceived and designed the experiments	Project administration	YES
5479773	28641405	KT	2	performed the experiment of genome analysis|analyzed the results of genome analysis	performed the experiment of genome analysis	Performed the experiments	Investigation	YES
5479773	28641405	KT	2	performed the experiment of genome analysis|analyzed the results of genome analysis	analyzed the results of genome analysis	Analyzed the data	Formal analysis	YES
5479773	28641405	KY	2	analyzed the results of genome analysis	analyzed the results of genome analysis	Analyzed the data	Formal analysis	YES
5479773	28641405	MM	2	participated in discussion	participated in discussion	-	-	NO
5479773	28641405	NO	2	designed the experiments, performed the experiments, analyzed the results, and wrote the manuscript	designed the experiments, performed the experiments, analyzed the results, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5479773	28641405	TM	2	participated in discussion	participated in discussion	-	-	NO
5479773	28641405	YT	2	performed the experiments of fermentation	performed the experiments of fermentation	Performed the experiments	Investigation	YES
1950569	17726543	KM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1950569	17726543	KM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1950569	17726543	KM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1950569	17726543	KM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1950569	17726543	NK	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1950569	17726543	NK	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1950569	17726543	ST	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1950569	17726543	TT	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1950569	17726543	TT	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1950569	17726543	TY	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4581032	26056371	All authors	2	gave final approval of the version to be published	gave final approval of the version to be published	-	-	NO
4581032	26056371	D.E.B.	2	contributed to data acquisition, analysis and interpretation, wrote and reviewed the article	contributed to data acquisition, analysis and interpretation, wrote and reviewed the article	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
4581032	26056371	E.E.S.	2	contributed to data acquisition, analysis and interpretation, and reviewed the article	contributed to data acquisition, analysis and interpretation, and reviewed the article	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
4581032	26056371	J.D.H.	2	contributed to the study conception and design, and reviewed the article	contributed to the study conception and design, and reviewed the article	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
4581032	26056371	M.K.G.	2	contributed to data acquisition, analysis and interpretation, wrote and reviewed the article	contributed to data acquisition, analysis and interpretation, wrote and reviewed the article	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
4581032	26056371	P.N.O.	2	contributed to the study conception and design, and reviewed the article	contributed to the study conception and design, and reviewed the article	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
4581032	26056371	R.L.P.	2	contributed to the study conception and design, analysis and interpretation of data, wrote and reviewed the article	contributed to the study conception and design, analysis and interpretation of data, wrote and reviewed the article	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
4581032	26056371	W.A.J.	2	contributed to the study conception and design, and reviewed the article	contributed to the study conception and design, and reviewed the article	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
4628763	26557658	Constance Fearnley	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
4628763	26557658	Kathryn Fackrell	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
5788904	29422912	FQ	CRediT	Writing-original draft|Writing-review and editing	Writing-original draft	Wrote the paper	Writing - Original Draft	YES
5788904	29422912	FQ	CRediT	Writing-original draft|Writing-review and editing	Writing-review and editing	Wrote the paper	Writing - Review & Editing	YES
5788904	29422912	QG	CRediT	Writing-review and editing	Writing-review and editing	Wrote the paper	Writing - Review & Editing	YES
5788904	29422912	RS	CRediT	Writing-review and editing	Writing-review and editing	Wrote the paper	Writing - Review & Editing	YES
5788904	29422912	SZ	CRediT	Writing-review and editing	Writing-review and editing	Wrote the paper	Writing - Review & Editing	YES
5788904	29422912	TW	CRediT	Writing-review and editing	Writing-review and editing	Wrote the paper	Writing - Review & Editing	YES
5788904	29422912	X-FZ	CRediT	Writing-original draft|Writing-review and editing	Writing-original draft	Wrote the paper	Writing - Original Draft	YES
5788904	29422912	X-FZ	CRediT	Writing-original draft|Writing-review and editing	Writing-review and editing	Wrote the paper	Writing - Review & Editing	YES
4416713	25933226	HK	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416713	25933226	HK	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416713	25933226	KA	PLoS5	Conceived and designed the experiments|Significant critical input	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416713	25933226	KA	PLoS5	Conceived and designed the experiments|Significant critical input	Significant critical input	-	-	NO
4416713	25933226	MT	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416713	25933226	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Significant critical input	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416713	25933226	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Significant critical input	Performed the experiments	Performed the experiments	Investigation	YES
4416713	25933226	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Significant critical input	Analyzed the data	Analyzed the data	Formal analysis	YES
4416713	25933226	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Significant critical input	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416713	25933226	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Significant critical input	Significant critical input	-	-	NO
4416713	25933226	SO	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416713	25933226	SO	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416713	25933226	T. Kawamata	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416713	25933226	T. Kawamata	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416713	25933226	T. Kimotsuki	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416713	25933226	T. Kobayashi	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416713	25933226	TN	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416713	25933226	TN	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416713	25933226	YS	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416713	25933226	YS	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416713	25933226	YT	PLoS5	Conceived and designed the experiments|Significant critical input	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416713	25933226	YT	PLoS5	Conceived and designed the experiments|Significant critical input	Significant critical input	-	-	NO
5709737	29074627	BR	CRediT	Provided methodology|resources|Analyzed data	Provided methodology	Performed the experiments	Methodology	YES
5709737	29074627	BR	CRediT	Provided methodology|resources|Analyzed data	resources	Contributed reagents/materials/analysis tools	Resources	YES
5709737	29074627	BR	CRediT	Provided methodology|resources|Analyzed data	Analyzed data	Analyzed the data	Formal analysis	YES
5709737	29074627	CA	CRediT	Performed experiments	Performed experiments	Performed the experiments	Investigation	YES
5709737	29074627	JW	CRediT	Performed experiments|Analyzed data	Performed experiments	Performed the experiments	Investigation	YES
5709737	29074627	JW	CRediT	Performed experiments|Analyzed data	Analyzed data	Analyzed the data	Formal analysis	YES
5709737	29074627	MM	CRediT	Performed experiments|Analyzed data	Performed experiments	Performed the experiments	Investigation	YES
5709737	29074627	MM	CRediT	Performed experiments|Analyzed data	Analyzed data	Analyzed the data	Formal analysis	YES
5709737	29074627	RV	CRediT	Performed experiments|Provided methodology|resources	Performed experiments	Performed the experiments	Investigation	YES
5709737	29074627	RV	CRediT	Performed experiments|Provided methodology|resources	Provided methodology	Performed the experiments	Methodology	YES
5709737	29074627	RV	CRediT	Performed experiments|Provided methodology|resources	resources	Contributed reagents/materials/analysis tools	Resources	YES
5709737	29074627	TB	CRediT	Performed experiments|Analyzed data|Designed study, supervised experiments, and wrote manuscript	Performed experiments	Performed the experiments	Investigation	YES
5709737	29074627	TB	CRediT	Performed experiments|Analyzed data|Designed study, supervised experiments, and wrote manuscript	Analyzed data	Analyzed the data	Formal analysis	YES
5709737	29074627	TB	CRediT	Performed experiments|Analyzed data|Designed study, supervised experiments, and wrote manuscript	Designed study, supervised experiments, and wrote manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Original Draft	YES
5716225	29202705	DBSS	PLoS52	analyzed and interpreted the results	analyzed and interpreted the results	Analyzed the data	Formal analysis	YES
5716225	29202705	DFJG	PLoS52	conceived and designed the experiment|performed the experiments	conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5716225	29202705	DFJG	PLoS52	conceived and designed the experiment|performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5716225	29202705	FB	PLoS52	conceived and designed the experiment	conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5716225	29202705	JAF	PLoS52	conceived and designed the experiment	conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5716225	29202705	JAP	PLoS52	drafted and revised the manuscript	drafted and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5716225	29202705	LFSF	PLoS52	conceived and designed the experiment|performed the experiments|analyzed and interpreted the results|drafted and revised the manuscript	conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5716225	29202705	LFSF	PLoS52	conceived and designed the experiment|performed the experiments|analyzed and interpreted the results|drafted and revised the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5716225	29202705	LFSF	PLoS52	conceived and designed the experiment|performed the experiments|analyzed and interpreted the results|drafted and revised the manuscript	analyzed and interpreted the results	Analyzed the data	Formal analysis	YES
5716225	29202705	LFSF	PLoS52	conceived and designed the experiment|performed the experiments|analyzed and interpreted the results|drafted and revised the manuscript	drafted and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5716225	29202705	LGA	PLoS52	conceived and designed the experiment|analyzed and interpreted the results|drafted and revised the manuscript	conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5716225	29202705	LGA	PLoS52	conceived and designed the experiment|analyzed and interpreted the results|drafted and revised the manuscript	analyzed and interpreted the results	Analyzed the data	Formal analysis	YES
5716225	29202705	LGA	PLoS52	conceived and designed the experiment|analyzed and interpreted the results|drafted and revised the manuscript	drafted and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5716225	29202705	RB	PLoS52	analyzed and interpreted the results|drafted and revised the manuscript	analyzed and interpreted the results	Analyzed the data	Formal analysis	YES
5716225	29202705	RB	PLoS52	analyzed and interpreted the results|drafted and revised the manuscript	drafted and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6042354	29996843	AM	2	aided in subject visits, data collection and writing the manuscript	aided in subject visits, data collection and writing the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6042354	29996843	BTW	2	was the staff phlebotomist, assisted in protocol development, aided in data collection and analysis, and was major contributor to writing the manuscript	was the staff phlebotomist, assisted in protocol development, aided in data collection and analysis, and was major contributor to writing the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
6042354	29996843	CM	2	aided in subject visits, data collection and developing graphs for the manuscript	aided in subject visits, data collection and developing graphs for the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6042354	29996843	PJH	2	was the principal investigator overseeing all research activity, assisted in protocol development and was a major contributor to writing the manuscript	was the principal investigator overseeing all research activity, assisted in protocol development and was a major contributor to writing the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Funding acquisition|Methodology|Supervision|Writing - Original Draft	YES
6042354	29996843	TF	2	assisted in protocol development, scheduled and conducted subject visits, collected data, analyzed data and was a major contributor to writing the manuscript	assisted in protocol development, scheduled and conducted subject visits, collected data, analyzed data and was a major contributor to writing the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
6042354	29996843	ZML	2	aided with phlebotomy and contributed to the figures	aided with phlebotomy and contributed to the figures	-	Visualization	YES
1950570	17786196	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1950570	17786196	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1950570	17786196	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1950570	17786196	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1950570	17786196	NS	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1950570	17786196	SS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Wrote the first draft of the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1950570	17786196	SS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Wrote the first draft of the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1950570	17786196	SS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Wrote the first draft of the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1950570	17786196	SS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Wrote the first draft of the paper	Wrote the first draft of the paper	Wrote the paper	Writing - Original Draft	YES
5788914	29422910	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Drafted the manuscript and figures	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5788914	29422910	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Drafted the manuscript and figures	Performed the experiments	Performed the experiments	Investigation	YES
5788914	29422910	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Drafted the manuscript and figures	Analyzed the data	Analyzed the data	Formal analysis	YES
5788914	29422910	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Drafted the manuscript and figures	Drafted the manuscript and figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5788914	29422910	DG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5788914	29422910	EP	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5788914	29422910	HM	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5788914	29422910	TG	PLoS5	Conceived and designed the experiments|Contributed materials	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5788914	29422910	TG	PLoS5	Conceived and designed the experiments|Contributed materials	Contributed materials	Contributed reagents/materials/analysis tools	Resources	YES
5788914	29422910	WM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed materials	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5788914	29422910	WM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed materials	Performed the experiments	Performed the experiments	Investigation	YES
5788914	29422910	WM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed materials	Contributed materials	Contributed reagents/materials/analysis tools	Resources	YES
5479774	28641403	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5479774	28641403	CL	2	carried out the studies related to the analysis of fos	carried out the studies related to the analysis of fos	Performed the experiments	Investigation	YES
5479774	28641403	GS	2	contributed in data interpretation and coordination	contributed in data interpretation and coordination	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Project administration|Resources	YES
5479774	28641403	HZ	2	participated in the isolation of fungi	participated in the isolation of fungi	Performed the experiments	Investigation	YES
5479774	28641403	JZ	2	carried out the studies related to the analysis of fos	carried out the studies related to the analysis of fos	Performed the experiments	Investigation	YES
5479774	28641403	NL	2	participated in the fungal taxonomic characterization	participated in the fungal taxonomic characterization	Performed the experiments	Investigation	YES
5479774	28641403	YX	2	designed the work, performed the research study and drafted the manuscript	designed the work, performed the research study and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5479774	28641403	YZ	2	designed the work, performed the research study and drafted the manuscript	designed the work, performed the research study and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5479774	28641403	ZZ	2	participated in the fungal taxonomic characterization	participated in the fungal taxonomic characterization	Performed the experiments	Investigation	YES
4416714	25933391	EC	PLoS5	Contributed autopsy samples|Critical review of the manuscript	Contributed autopsy samples	Contributed reagents/materials/analysis tools	Resources	YES
4416714	25933391	EC	PLoS5	Contributed autopsy samples|Critical review of the manuscript	Critical review of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4416714	25933391	GDP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Critical review of the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416714	25933391	GDP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Critical review of the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416714	25933391	GDP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Critical review of the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416714	25933391	GDP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Critical review of the manuscript	Critical review of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4416714	25933391	GMP	PLoS5	Contributed reagents/materials/analysis tools|Critical review of the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416714	25933391	GMP	PLoS5	Contributed reagents/materials/analysis tools|Critical review of the manuscript	Critical review of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4416714	25933391	JHL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Critical review of the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416714	25933391	JHL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Critical review of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4416714	25933391	JHL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Critical review of the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416714	25933391	JHL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Critical review of the manuscript	Critical review of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4416714	25933391	JPV	PLoS5	Contributed autopsy samples|Critical review of the manuscript	Contributed autopsy samples	Contributed reagents/materials/analysis tools	Resources	YES
4416714	25933391	JPV	PLoS5	Contributed autopsy samples|Critical review of the manuscript	Critical review of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4416714	25933391	KM	PLoS5	Contributed autopsy samples|Critical review of the manuscript	Contributed autopsy samples	Contributed reagents/materials/analysis tools	Resources	YES
4416714	25933391	KM	PLoS5	Contributed autopsy samples|Critical review of the manuscript	Critical review of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4416714	25933391	LLH	PLoS5	Contributed autopsy samples|Critical review of the manuscript	Contributed autopsy samples	Contributed reagents/materials/analysis tools	Resources	YES
4416714	25933391	LLH	PLoS5	Contributed autopsy samples|Critical review of the manuscript	Critical review of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4416714	25933391	LNC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Critical review of the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416714	25933391	LNC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Critical review of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4416714	25933391	LNC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Critical review of the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416714	25933391	LNC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Critical review of the manuscript	Critical review of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4416714	25933391	MS	PLoS5	Contributed autopsy samples|Critical review of the manuscript	Contributed autopsy samples	Contributed reagents/materials/analysis tools	Resources	YES
4416714	25933391	MS	PLoS5	Contributed autopsy samples|Critical review of the manuscript	Critical review of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4416714	25933391	N. Park	PLoS5	Analyzed the data|Critical review of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4416714	25933391	N. Park	PLoS5	Analyzed the data|Critical review of the manuscript	Critical review of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4416714	25933391	N. Parmalee	PLoS5	Performed the experiments|Analyzed the data|Critical review of the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4416714	25933391	N. Parmalee	PLoS5	Performed the experiments|Analyzed the data|Critical review of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4416714	25933391	N. Parmalee	PLoS5	Performed the experiments|Analyzed the data|Critical review of the manuscript	Critical review of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4416714	25933391	PAT	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Critical review of the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4416714	25933391	PAT	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Critical review of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4416714	25933391	PAT	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Critical review of the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416714	25933391	PAT	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Critical review of the manuscript	Critical review of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4416714	25933391	R. Chan	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Critical review of the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416714	25933391	R. Chan	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Critical review of the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4416714	25933391	R. Chan	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Critical review of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4416714	25933391	R. Chan	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Critical review of the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416714	25933391	R. Chan	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Critical review of the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416714	25933391	R. Chan	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Critical review of the manuscript	Critical review of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4416714	25933391	R. Cheng	PLoS5	Analyzed the data|Critical review of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4416714	25933391	R. Cheng	PLoS5	Analyzed the data|Critical review of the manuscript	Critical review of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4416714	25933391	RA	PLoS5	Contributed autopsy samples|Critical review of the manuscript	Contributed autopsy samples	Contributed reagents/materials/analysis tools	Resources	YES
4416714	25933391	RA	PLoS5	Contributed autopsy samples|Critical review of the manuscript	Critical review of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4416714	25933391	RM	PLoS5	Contributed autopsy samples|Critical review of the manuscript	Contributed autopsy samples	Contributed reagents/materials/analysis tools	Resources	YES
4416714	25933391	RM	PLoS5	Contributed autopsy samples|Critical review of the manuscript	Critical review of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4416714	25933391	SF	PLoS5	Critical review of the manuscript	Critical review of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4416714	25933391	SK	PLoS5	Performed the experiments|Analyzed the data|Critical review of the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4416714	25933391	SK	PLoS5	Performed the experiments|Analyzed the data|Critical review of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4416714	25933391	SK	PLoS5	Performed the experiments|Analyzed the data|Critical review of the manuscript	Critical review of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4416714	25933391	XL	PLoS5	Analyzed the data|Critical review of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4416714	25933391	XL	PLoS5	Analyzed the data|Critical review of the manuscript	Critical review of the manuscript	Wrote the paper	Writing - Review & Editing	YES
1950573	17726544	CL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1950573	17726544	CL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1950573	17726544	CL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1950573	17726544	QW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1950573	17726544	QW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1950573	17726544	QW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1950573	17726544	QW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5716240	29202694	CLC	2	and wcb4 designed the study|prepared the samples|and wcb4 analyzed the data|and wcb4 wrote the manuscript	and wcb4 designed the study	Conceived and designed the experiments	Methodology	YES
5716240	29202694	CLC	2	and wcb4 designed the study|prepared the samples|and wcb4 analyzed the data|and wcb4 wrote the manuscript	prepared the samples	Performed the experiments	Investigation	YES
5716240	29202694	CLC	2	and wcb4 designed the study|prepared the samples|and wcb4 analyzed the data|and wcb4 wrote the manuscript	and wcb4 analyzed the data	Analyzed the data	Formal analysis	YES
5716240	29202694	CLC	2	and wcb4 designed the study|prepared the samples|and wcb4 analyzed the data|and wcb4 wrote the manuscript	and wcb4 wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5716240	29202694	FJ	2	provided the capture probe and gave technical advice on preparation details, probe design and capture probe details	provided the capture probe and gave technical advice on preparation details, probe design and capture probe details	Conceived and designed the experiments	-	YES
5716240	29202694	LBD	2	and wcb4 designed the study|prepared the samples	and wcb4 designed the study	Conceived and designed the experiments	Methodology	YES
5716240	29202694	LBD	2	and wcb4 designed the study|prepared the samples	prepared the samples	Performed the experiments	Investigation	YES
5716240	29202694	PJ	2	provided the capture probe and gave technical advice on preparation details, probe design and capture probe details	provided the capture probe and gave technical advice on preparation details, probe design and capture probe details	Conceived and designed the experiments	-	YES
5716240	29202694	SLF	2	wrote scripts and provided guidance on data analysis	wrote scripts and provided guidance on data analysis	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Software|Supervision|Writing - Original Draft	YES
5709738	29046335	FS	2	directed study, conceived and designed experiments, designed and cloned constructs, carried out protein purification, biochemical experiments, light scattering measurements, electron microscopy, sedimentation-equilibrium analytical ultracentrifugation measurements, yeast genetic modifications, co-immunoprecipitation experiments, live cell microscopy, protein crystallization, x-ray diffraction data collection, and crystal structure determination and analysed resultant data|interpreted mass spectra|revised the manuscript	directed study, conceived and designed experiments, designed and cloned constructs, carried out protein purification, biochemical experiments, light scattering measurements, electron microscopy, sedimentation-equilibrium analytical ultracentrifugation measurements, yeast genetic modifications, co-immunoprecipitation experiments, live cell microscopy, protein crystallization, x-ray diffraction data collection, and crystal structure determination and analysed resultant data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation|Methodology|Supervision	YES
5709738	29046335	FS	2	directed study, conceived and designed experiments, designed and cloned constructs, carried out protein purification, biochemical experiments, light scattering measurements, electron microscopy, sedimentation-equilibrium analytical ultracentrifugation measurements, yeast genetic modifications, co-immunoprecipitation experiments, live cell microscopy, protein crystallization, x-ray diffraction data collection, and crystal structure determination and analysed resultant data|interpreted mass spectra|revised the manuscript	interpreted mass spectra	Analyzed the data	Formal analysis	YES
5709738	29046335	FS	2	directed study, conceived and designed experiments, designed and cloned constructs, carried out protein purification, biochemical experiments, light scattering measurements, electron microscopy, sedimentation-equilibrium analytical ultracentrifugation measurements, yeast genetic modifications, co-immunoprecipitation experiments, live cell microscopy, protein crystallization, x-ray diffraction data collection, and crystal structure determination and analysed resultant data|interpreted mass spectra|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5709738	29046335	MMR	2	designed and carried out hydrogen-deuterium-exchange mass spectrometry experiments and analysed resultant data|interpreted mass spectra	designed and carried out hydrogen-deuterium-exchange mass spectrometry experiments and analysed resultant data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5709738	29046335	MMR	2	designed and carried out hydrogen-deuterium-exchange mass spectrometry experiments and analysed resultant data|interpreted mass spectra	interpreted mass spectra	Analyzed the data	Formal analysis	YES
5709738	29046335	SW	2	conceived and advised on yeast genetic experiments and carried out co-immunoprecipitation experiments and size-exclusion chromatography experiments for revised manuscript	conceived and advised on yeast genetic experiments and carried out co-immunoprecipitation experiments and size-exclusion chromatography experiments for revised manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Review & Editing	YES
5709738	29046335	YG	2	designed and carried out nanoflow electrospray mass spectrometry experiments and analysed resultant data|interpreted mass spectra	designed and carried out nanoflow electrospray mass spectrometry experiments and analysed resultant data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5709738	29046335	YG	2	designed and carried out nanoflow electrospray mass spectrometry experiments and analysed resultant data|interpreted mass spectra	interpreted mass spectra	Analyzed the data	Formal analysis	YES
4628765	26557660	Jae-Hoon Kim	2	contributed equally to this work	contributed equally to this work	-	-	NO
4628765	26557660	Yoon Lee	2	contributed equally to this work	contributed equally to this work	-	-	NO
6050691	30016961	BK	2	critically reviewed it	critically reviewed it	-	-	NO
6050691	30016961	KW	2	critically reviewed it	critically reviewed it	-	-	NO
6050691	30016961	PN	2	performed data analysis	performed data analysis	Analyzed the data	Formal analysis	YES
1950574	17786197	AL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1950574	17786197	AL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1950574	17786197	AL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1950574	17786197	AL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1950574	17786197	AL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1950574	17786197	BA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1950574	17786197	BA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1950574	17786197	BA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1950574	17786197	BA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1950574	17786197	BR	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1950574	17786197	BR	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1950574	17786197	CL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1950574	17786197	CS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1950574	17786197	CS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1950574	17786197	CS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1950574	17786197	CS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1950574	17786197	DK	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1950574	17786197	GG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1950574	17786197	GG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1950574	17786197	GG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1950574	17786197	GG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1950574	17786197	IL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1950574	17786197	JM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1950574	17786197	LT	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1950574	17786197	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1950574	17786197	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1950574	17786197	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1950574	17786197	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1950574	17786197	MS	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1950574	17786197	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1950574	17786197	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1950574	17786197	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1950574	17786197	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1950574	17786197	UJ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5479777	28641406	AM	2	wrote and edited the manuscript	wrote and edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5479777	28641406	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5479777	28641406	HI	2	prepared and analyzed the peptide	prepared and analyzed the peptide	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5479777	28641406	HW	2	prepared and analyzed the peptide	prepared and analyzed the peptide	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5479777	28641406	MK	2	performed microbiological experiments	performed microbiological experiments	Performed the experiments	Investigation	YES
5479777	28641406	RK	2	performed microbiological experiments	performed microbiological experiments	Performed the experiments	Investigation	YES
5479777	28641406	SYa	2	performed microbiological experiments	performed microbiological experiments	Performed the experiments	Investigation	YES
5479777	28641406	SYo	2	performed microbiological experiments|wrote and edited the manuscript	performed microbiological experiments	Performed the experiments	Investigation	YES
5479777	28641406	SYo	2	performed microbiological experiments|wrote and edited the manuscript	wrote and edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5479777	28641406	TSa	2	performed microbiological experiments	performed microbiological experiments	Performed the experiments	Investigation	YES
5479777	28641406	TSh	2	performed microbiological experiments|wrote and edited the manuscript	performed microbiological experiments	Performed the experiments	Investigation	YES
5479777	28641406	TSh	2	performed microbiological experiments|wrote and edited the manuscript	wrote and edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5479777	28641406	YO	2	performed microbiological experiments	performed microbiological experiments	Performed the experiments	Investigation	YES
4416715	25933356	AAA	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416715	25933356	AAA	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416715	25933356	AAA	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416715	25933356	DO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416715	25933356	DO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416715	25933356	DO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416715	25933356	DO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416715	25933356	DO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416715	25933356	FF	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416715	25933356	FF	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416715	25933356	FF	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416715	25933356	IE	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416715	25933356	IE	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416715	25933356	IE	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416715	25933356	OI	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416715	25933356	OI	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416715	25933356	OI	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416715	25933356	TH	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416715	25933356	TH	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416715	25933356	TH	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416715	25933356	WT	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416715	25933356	WT	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416715	25933356	WT	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5788969	29422908	All authors	PLoS52	reviewed and approved the final manuscript	reviewed and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5788969	29422908	B-YL	PLoS52	collected plant material	collected plant material	Performed the experiments	Investigation	YES
5788969	29422908	D-ZL	PLoS52	conceived and designed the study|wrote and revised the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5788969	29422908	D-ZL	PLoS52	conceived and designed the study|wrote and revised the manuscript	wrote and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5788969	29422908	J-BY	PLoS52	collected plant material	collected plant material	Performed the experiments	Investigation	YES
5788969	29422908	J-CX	PLoS52	conceived and designed the study|collected plant material|wrote and revised the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5788969	29422908	J-CX	PLoS52	conceived and designed the study|collected plant material|wrote and revised the manuscript	collected plant material	Performed the experiments	Investigation	YES
5788969	29422908	J-CX	PLoS52	conceived and designed the study|collected plant material|wrote and revised the manuscript	wrote and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5788969	29422908	JL	PLoS52	analyzed and interpreted the data|wrote and revised the manuscript	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5788969	29422908	JL	PLoS52	analyzed and interpreted the data|wrote and revised the manuscript	wrote and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5788969	29422908	KT	PLoS52	collected plant material	collected plant material	Performed the experiments	Investigation	YES
5788969	29422908	L-MG	PLoS52	conceived and designed the study|collected plant material|analyzed and interpreted the data|wrote and revised the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5788969	29422908	L-MG	PLoS52	conceived and designed the study|collected plant material|analyzed and interpreted the data|wrote and revised the manuscript	collected plant material	Performed the experiments	Investigation	YES
5788969	29422908	L-MG	PLoS52	conceived and designed the study|collected plant material|analyzed and interpreted the data|wrote and revised the manuscript	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5788969	29422908	L-MG	PLoS52	conceived and designed the study|collected plant material|analyzed and interpreted the data|wrote and revised the manuscript	wrote and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5788969	29422908	M-ML	PLoS52	collected plant material|performed the experiments	collected plant material	Performed the experiments	Investigation	YES
5788969	29422908	M-ML	PLoS52	collected plant material|performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5788969	29422908	MKM	PLoS52	collected plant material|performed the experiments|analyzed and interpreted the data|wrote and revised the manuscript	collected plant material	Performed the experiments	Investigation	YES
5788969	29422908	MKM	PLoS52	collected plant material|performed the experiments|analyzed and interpreted the data|wrote and revised the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5788969	29422908	MKM	PLoS52	collected plant material|performed the experiments|analyzed and interpreted the data|wrote and revised the manuscript	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5788969	29422908	MKM	PLoS52	collected plant material|performed the experiments|analyzed and interpreted the data|wrote and revised the manuscript	wrote and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5788969	29422908	MM	PLoS52	analyzed and interpreted the data|wrote and revised the manuscript	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5788969	29422908	MM	PLoS52	analyzed and interpreted the data|wrote and revised the manuscript	wrote and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5788969	29422908	MW	PLoS52	performed the experiments|analyzed and interpreted the data|wrote and revised the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5788969	29422908	MW	PLoS52	performed the experiments|analyzed and interpreted the data|wrote and revised the manuscript	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5788969	29422908	MW	PLoS52	performed the experiments|analyzed and interpreted the data|wrote and revised the manuscript	wrote and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5788969	29422908	Y-SS	PLoS52	analyzed and interpreted the data|wrote and revised the manuscript	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5788969	29422908	Y-SS	PLoS52	analyzed and interpreted the data|wrote and revised the manuscript	wrote and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4614726	26460122	M.M.H.	2	both conceptualized and wrote the article	both conceptualized and wrote the article	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4614726	26460122	P.J.F.	2	both conceptualized and wrote the article	both conceptualized and wrote the article	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
6057087	30041701	ASS	2	designed the study|interpreted the results and drafted the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
6057087	30041701	ASS	2	designed the study|interpreted the results and drafted the manuscript	interpreted the results and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6057087	30041701	AU	2	designed the study|interpreted the results and drafted the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
6057087	30041701	AU	2	designed the study|interpreted the results and drafted the manuscript	interpreted the results and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6057087	30041701	AW	2	collected the data	collected the data	Performed the experiments	Investigation	YES
6057087	30041701	EL	2	interpreted the results and drafted the manuscript	interpreted the results and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6057087	30041701	KA	2	designed the study|collected the data	designed the study	Conceived and designed the experiments	Methodology	YES
6057087	30041701	KA	2	designed the study|collected the data	collected the data	Performed the experiments	Investigation	YES
6057087	30041701	KWJ	2	collected the data	collected the data	Performed the experiments	Investigation	YES
6057087	30041701	PB	2	collected the data	collected the data	Performed the experiments	Investigation	YES
5717833	29212448	AP	2	designed the study and interpreted the data|were major contributors in writing the manuscript	designed the study and interpreted the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5717833	29212448	AP	2	designed the study and interpreted the data|were major contributors in writing the manuscript	were major contributors in writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5717833	29212448	BK	2	designed the study and interpreted the data|were major contributors in writing the manuscript	designed the study and interpreted the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5717833	29212448	BK	2	designed the study and interpreted the data|were major contributors in writing the manuscript	were major contributors in writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5717833	29212448	CW	2	designed the study and interpreted the data|were major contributors in writing the manuscript	designed the study and interpreted the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5717833	29212448	CW	2	designed the study and interpreted the data|were major contributors in writing the manuscript	were major contributors in writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5717833	29212448	JG	2	performed the dna extraction	performed the dna extraction	Performed the experiments	Investigation	YES
5717833	29212448	JL	2	performed the dna extraction	performed the dna extraction	Performed the experiments	Investigation	YES
5717833	29212448	JY	2	performed the dna extraction	performed the dna extraction	Performed the experiments	Investigation	YES
5717833	29212448	KS	2	designed the study and interpreted the data|were major contributors in writing the manuscript	designed the study and interpreted the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5717833	29212448	KS	2	designed the study and interpreted the data|were major contributors in writing the manuscript	were major contributors in writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5717833	29212448	MJ	2	designed the study and interpreted the data|analyzed the mlst data and drew the figure|were major contributors in writing the manuscript	designed the study and interpreted the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5717833	29212448	MJ	2	designed the study and interpreted the data|analyzed the mlst data and drew the figure|were major contributors in writing the manuscript	analyzed the mlst data and drew the figure	Analyzed the data	Formal analysis|Visualization	YES
5717833	29212448	MJ	2	designed the study and interpreted the data|analyzed the mlst data and drew the figure|were major contributors in writing the manuscript	were major contributors in writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5717833	29212448	MLST	2	dna sequencing	dna sequencing	Performed the experiments	Investigation	YES
5717833	29212448	WG	2	designed the study and interpreted the data|performed the dna extraction|analyzed the mlst data and drew the figure|were major contributors in writing the manuscript	designed the study and interpreted the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5717833	29212448	WG	2	designed the study and interpreted the data|performed the dna extraction|analyzed the mlst data and drew the figure|were major contributors in writing the manuscript	performed the dna extraction	Performed the experiments	Investigation	YES
5717833	29212448	WG	2	designed the study and interpreted the data|performed the dna extraction|analyzed the mlst data and drew the figure|were major contributors in writing the manuscript	analyzed the mlst data and drew the figure	Analyzed the data	Formal analysis|Visualization	YES
5717833	29212448	WG	2	designed the study and interpreted the data|performed the dna extraction|analyzed the mlst data and drew the figure|were major contributors in writing the manuscript	were major contributors in writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5717833	29212448	YP	2	analyzed the mlst data and drew the figure|were major contributors in writing the manuscript	analyzed the mlst data and drew the figure	Analyzed the data	Formal analysis|Visualization	YES
5717833	29212448	YP	2	analyzed the mlst data and drew the figure|were major contributors in writing the manuscript	were major contributors in writing the manuscript	Wrote the paper	Writing - Original Draft	YES
3876899	24453824	Lihua Zhou	2	contributed equally to this work	contributed equally to this work	-	-	NO
3876899	24453824	Rongmin Guo	2	contributed equally to this work	contributed equally to this work	-	-	NO
1950575	17726545	CP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1950575	17726545	CP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1950575	17726545	CP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1950575	17726545	DP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1950575	17726545	JD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1950575	17726545	JD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1950575	17726545	JD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1950575	17726545	JD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1950575	17726545	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1950575	17726545	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1950575	17726545	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1950575	17726545	MN	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5730846	29127155	ARB	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5730846	29127155	BP	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5730846	29127155	CP	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5730846	29127155	DB	2	performed experiments|designed experiments	performed experiments	Performed the experiments	Investigation	YES
5730846	29127155	DB	2	performed experiments|designed experiments	designed experiments	Conceived and designed the experiments	Methodology	YES
5730846	29127155	DHG	2	designed experiments	designed experiments	Conceived and designed the experiments	Methodology	YES
5730846	29127155	DMD	2	performed experiments|designed experiments	performed experiments	Performed the experiments	Investigation	YES
5730846	29127155	DMD	2	performed experiments|designed experiments	designed experiments	Conceived and designed the experiments	Methodology	YES
5730846	29127155	EM	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5730846	29127155	GB	2	designed experiments	designed experiments	Conceived and designed the experiments	Methodology	YES
5730846	29127155	MM	2	performed experiments|designed experiments|wrote the manuscript|conceived the project	performed experiments	Performed the experiments	Investigation	YES
5730846	29127155	MM	2	performed experiments|designed experiments|wrote the manuscript|conceived the project	designed experiments	Conceived and designed the experiments	Methodology	YES
5730846	29127155	MM	2	performed experiments|designed experiments|wrote the manuscript|conceived the project	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5730846	29127155	MM	2	performed experiments|designed experiments|wrote the manuscript|conceived the project	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5730846	29127155	MRW	2	performed experiments|designed experiments|wrote the manuscript	performed experiments	Performed the experiments	Investigation	YES
5730846	29127155	MRW	2	performed experiments|designed experiments|wrote the manuscript	designed experiments	Conceived and designed the experiments	Methodology	YES
5730846	29127155	MRW	2	performed experiments|designed experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5730846	29127155	MW	2	designed experiments	designed experiments	Conceived and designed the experiments	Methodology	YES
5730846	29127155	NR	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5730846	29127155	OS	2	designed experiments	designed experiments	Conceived and designed the experiments	Methodology	YES
5730846	29127155	RAS	2	performed experiments|designed experiments|wrote the manuscript	performed experiments	Performed the experiments	Investigation	YES
5730846	29127155	RAS	2	performed experiments|designed experiments|wrote the manuscript	designed experiments	Conceived and designed the experiments	Methodology	YES
5730846	29127155	RAS	2	performed experiments|designed experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5730846	29127155	RLM	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5730846	29127155	SNL	2	designed experiments	designed experiments	Conceived and designed the experiments	Methodology	YES
5482509	28050854	All authors	2	were involved in data interpretation and the writing of the paper|read and approved the final manuscript	were involved in data interpretation and the writing of the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5482509	28050854	All authors	2	were involved in data interpretation and the writing of the paper|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5482509	28050854	IP	2	western blot studies and participated in drafting the manuscript	western blot studies and participated in drafting the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5482509	28050854	QL	2	carried out the confocal microscopy analysis	carried out the confocal microscopy analysis	Performed the experiments	Investigation	YES
5482509	28050854	RX	2	performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
5482509	28050854	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5482509	28050854	XD	2	the corresponding author, designed research and participated in its coordination	the corresponding author, designed research and participated in its coordination	Conceived and designed the experiments	Methodology|Project administration	YES
4416716	25933420	AAA	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416716	25933420	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416716	25933420	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4416716	25933420	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416716	25933420	KM	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416716	25933420	KM	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416716	25933420	RI	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4416716	25933420	RI	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416716	25933420	SAA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416716	25933420	SAA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4416716	25933420	SAA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416716	25933420	SAQ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416716	25933420	SAQ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416716	25933420	SAQ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416716	25933420	SAQ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6057091	30041682	BK	2	contributed to study design, data collection, data analysis, major contribution to the writing of the manuscript	contributed to study design, data collection, data analysis, major contribution to the writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
6057091	30041682	CM	2	contributed to the study design, data collection, moderate editing of manuscript, and procurement of funds	contributed to the study design, data collection, moderate editing of manuscript, and procurement of funds	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Methodology|Resources|Writing - Review & Editing	YES
6057091	30041682	CW	2	contributed with data collection, assisted with data analysis, and moderate contributions to the editing of the manuscript	contributed with data collection, assisted with data analysis, and moderate contributions to the editing of the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Review & Editing	YES
6057091	30041682	EB	2	contributed to data collection, performed hrv analysis and interpretation, blood assay analysis, conducted literature review, and major contribution to the writing of the manuscript	contributed to data collection, performed hrv analysis and interpretation, blood assay analysis, conducted literature review, and major contribution to the writing of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
6057091	30041682	JM	2	contributed to study design, data statistical analysis, and moderate editing of manuscript	contributed to study design, data statistical analysis, and moderate editing of manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Review & Editing	YES
6057091	30041682	PB	2	contributed to study design, data collection, moderate editing of the manuscript	contributed to study design, data collection, moderate editing of the manuscript	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Methodology|Resources|Writing - Review & Editing	YES
6057091	30041682	WH	2	significant contribution to data collection, moderate editing of the manuscript	significant contribution to data collection, moderate editing of the manuscript	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Resources|Writing - Review & Editing	YES
5789531	29422911	GY	2	conducted field work and figures made	conducted field work and figures made	Performed the experiments	Investigation|Visualization	YES
5789531	29422911	XG	2	planned and designed the research|wrote the manuscript	planned and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5789531	29422911	XG	2	planned and designed the research|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5789531	29422911	YP	2	conducted field work and figures made	conducted field work and figures made	Performed the experiments	Investigation|Visualization	YES
5789531	29422911	YZ	2	planned and designed the research|performed the experiments and analyzed the data|wrote the manuscript	planned and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5789531	29422911	YZ	2	planned and designed the research|performed the experiments and analyzed the data|wrote the manuscript	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5789531	29422911	YZ	2	planned and designed the research|performed the experiments and analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6335621	30746082	All authors	2	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
6335621	30746082	Chen Yang	2	was responsible for x-ray crystal structure determinations and assisted the time-resolved spectroscopic measurements	was responsible for x-ray crystal structure determinations and assisted the time-resolved spectroscopic measurements	Performed the experiments	Investigation	YES
6335621	30746082	Chi-Ming Che	2	designed and initiated this research project|wrote the manuscript	designed and initiated this research project	Conceived and designed the experiments	Conceptualization|Methodology	YES
6335621	30746082	Chi-Ming Che	2	designed and initiated this research project|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6335621	30746082	Chun-Nam Lok	2	designed the biological experiments|wrote the manuscript	designed the biological experiments	Conceived and designed the experiments	Methodology	YES
6335621	30746082	Chun-Nam Lok	2	designed the biological experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6335621	30746082	Ka-Chung Tong	2	carried out the biological experiments	carried out the biological experiments	Performed the experiments	Investigation	YES
6335621	30746082	Tsz-Lung Lam	2	synthesized and characterized all complexes in this work, performed the spectroscopic and electrochemical measurements and carried out the photocatalytic reactions|wrote the manuscript	synthesized and characterized all complexes in this work, performed the spectroscopic and electrochemical measurements and carried out the photocatalytic reactions	Performed the experiments	Investigation	YES
6335621	30746082	Tsz-Lung Lam	2	synthesized and characterized all complexes in this work, performed the spectroscopic and electrochemical measurements and carried out the photocatalytic reactions|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6335621	30746082	Wai-Lun Kwong	2	carried out the biological experiments	carried out the biological experiments	Performed the experiments	Investigation	YES
4614736	26460132	P.J.F.	2	all contributed to the conception, design, drafting and revising for intellectual content and final checking and approval	all contributed to the conception, design, drafting and revising for intellectual content and final checking and approval	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4614736	26460132	P.V.	2	all contributed to the conception, design, drafting and revising for intellectual content and final checking and approval	all contributed to the conception, design, drafting and revising for intellectual content and final checking and approval	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4614736	26460132	R.L.P.	2	all contributed to the conception, design, drafting and revising for intellectual content and final checking and approval	all contributed to the conception, design, drafting and revising for intellectual content and final checking and approval	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
1950683	17786213	AG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1950683	17786213	AG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1950683	17786213	AG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1950683	17786213	AG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1950683	17786213	AG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1950683	17786213	SM	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5718033	29207953	CT	PLoS52	conceived and designed the experiments|collected the samples|analyzed the data and wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5718033	29207953	CT	PLoS52	conceived and designed the experiments|collected the samples|analyzed the data and wrote the paper	collected the samples	Performed the experiments	Investigation	YES
5718033	29207953	CT	PLoS52	conceived and designed the experiments|collected the samples|analyzed the data and wrote the paper	analyzed the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5718033	29207953	FT	PLoS52	collected the samples	collected the samples	Performed the experiments	Investigation	YES
5718033	29207953	KZ	PLoS52	conceived and designed the experiments|collected the samples	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5718033	29207953	KZ	PLoS52	conceived and designed the experiments|collected the samples	collected the samples	Performed the experiments	Investigation	YES
4416718	25933224	CLC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416718	25933224	FYL	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416718	25933224	FYL	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416718	25933224	HCH	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416718	25933224	HCH	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416718	25933224	HCL	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416718	25933224	HCT	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416718	25933224	HCT	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416718	25933224	JYL	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416718	25933224	MHT	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416718	25933224	SDL	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416718	25933224	SSW	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416718	25933224	TIH	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5730859	29217590	HBB	2	contributed equally to the study|prepared the figures|wrote the manuscript with input from all authors	contributed equally to the study	-	-	NO
5730859	29217590	HBB	2	contributed equally to the study|prepared the figures|wrote the manuscript with input from all authors	prepared the figures	-	Visualization	YES
5730859	29217590	HBB	2	contributed equally to the study|prepared the figures|wrote the manuscript with input from all authors	wrote the manuscript with input from all authors	Wrote the paper	Writing - Original Draft	YES
5730859	29217590	IMF	2	performed image analysis|prepared the figures|wrote the manuscript with input from all authors	performed image analysis	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
5730859	29217590	IMF	2	performed image analysis|prepared the figures|wrote the manuscript with input from all authors	prepared the figures	-	Visualization	YES
5730859	29217590	IMF	2	performed image analysis|prepared the figures|wrote the manuscript with input from all authors	wrote the manuscript with input from all authors	Wrote the paper	Writing - Original Draft	YES
5730859	29217590	J-MP	2	provided a novel mouse strain	provided a novel mouse strain	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5730859	29217590	JG	2	contributed equally to the study|prepared the figures|wrote the manuscript with input from all authors	contributed equally to the study	-	-	NO
5730859	29217590	JG	2	contributed equally to the study|prepared the figures|wrote the manuscript with input from all authors	prepared the figures	-	Visualization	YES
5730859	29217590	JG	2	contributed equally to the study|prepared the figures|wrote the manuscript with input from all authors	wrote the manuscript with input from all authors	Wrote the paper	Writing - Original Draft	YES
5730859	29217590	KT	2	conceived the project|wrote the manuscript with input from all authors	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5730859	29217590	KT	2	conceived the project|wrote the manuscript with input from all authors	wrote the manuscript with input from all authors	Wrote the paper	Writing - Original Draft	YES
5730859	29217590	LAM	2	developed and performed snhi-c data analysis and simulations|wrote the manuscript with input from all authors	developed and performed snhi-c data analysis and simulations	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5730859	29217590	LAM	2	developed and performed snhi-c data analysis and simulations|wrote the manuscript with input from all authors	wrote the manuscript with input from all authors	Wrote the paper	Writing - Original Draft	YES
5730859	29217590	MI	2	performed simulations|prepared the figures|wrote the manuscript with input from all authors	performed simulations	Performed the experiments	Formal analysis|Investigation	YES
5730859	29217590	MI	2	performed simulations|prepared the figures|wrote the manuscript with input from all authors	prepared the figures	-	Visualization	YES
5730859	29217590	MI	2	performed simulations|prepared the figures|wrote the manuscript with input from all authors	wrote the manuscript with input from all authors	Wrote the paper	Writing - Original Draft	YES
5730859	29217590	SL	2	provided novel mouse strains and imaging reagents	provided novel mouse strains and imaging reagents	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Investigation|Resources|Visualization	YES
5730859	29217590	WAB	2	wrote the manuscript with input from all authors	wrote the manuscript with input from all authors	Wrote the paper	Writing - Original Draft	YES
5482794	28651380	ABA	2	designed the study, analysed and interpreted the data	designed the study, analysed and interpreted the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5482794	28651380	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5482794	28651380	BMY	2	conducted the study and collected the data	conducted the study and collected the data	Performed the experiments	Investigation	YES
5482794	28651380	HW	2	designed the study, analysed and interpreted the data	designed the study, analysed and interpreted the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5482794	28651380	JST	2	designed the study, analysed and interpreted the data	designed the study, analysed and interpreted the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5482794	28651380	MH	2	designed the study, analysed and interpreted the data, and wrote the manuscript	designed the study, analysed and interpreted the data, and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5482794	28651380	NBMZ	2	conducted the study, collected the data, analysed and interpreted the data, and wrote the manuscript	conducted the study, collected the data, analysed and interpreted the data, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5482794	28651380	SNO	2	designed the study, analysed and interpreted the data	designed the study, analysed and interpreted the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
1950684	17786205	GC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1950684	17786205	GC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1950684	17786205	GC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1950684	17786205	JS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1950684	17786205	JS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1950684	17786205	MH	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1950684	17786205	MH	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1950684	17786205	MY	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1950684	17786205	RH	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1950684	17786205	RH	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1950684	17786205	SC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1950684	17786205	SC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1950684	17786205	SC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1950684	17786205	SV	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1950684	17786205	SV	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5718139	29207949	ALW	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5718139	29207949	All authors	2	read, edited and approved the final manuscript	read, edited and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5718139	29207949	ND	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5718139	29207949	OC	2	designed the study|performed the experiments and bioinformatics analysis and drafted the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5718139	29207949	OC	2	designed the study|performed the experiments and bioinformatics analysis and drafted the manuscript	performed the experiments and bioinformatics analysis and drafted the manuscript	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6069865	30064450	AC	4	data were collected by	data were collected by	Performed the experiments	Investigation	YES
6069865	30064450	AH	4	data were collected by	data were collected by	Performed the experiments	Investigation	YES
6069865	30064450	JMC	4	The present study was designed by|data were collected by|data interpretation and manuscript preparation was undertaken by	The present study was designed by	Conceived and designed the experiments	Methodology	YES
6069865	30064450	JMC	4	The present study was designed by|data were collected by|data interpretation and manuscript preparation was undertaken by	data were collected by	Performed the experiments	Investigation	YES
6069865	30064450	JMC	4	The present study was designed by|data were collected by|data interpretation and manuscript preparation was undertaken by	data interpretation and manuscript preparation was undertaken by	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6069865	30064450	KB	4	data were collected by|data were collected by	data were collected by	Performed the experiments	Investigation	YES
6069865	30064450	KB	4	data were collected by|data were collected by	data were collected by	Performed the experiments	Investigation	YES
6069865	30064450	MB	4	data were collected by	data were collected by	Performed the experiments	Investigation	YES
6069865	30064450	SAC	4	data interpretation and manuscript preparation was undertaken by	data interpretation and manuscript preparation was undertaken by	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6069865	30064450	TC	4	data were collected by	data were collected by	Performed the experiments	Investigation	YES
5789609	29422907	HL	1	Data cultivation and collection	Data cultivation and collection	Performed the experiments	Investigation	YES
5789609	29422907	HZhang	1	Project design|Data cultivation and collection|Data analysis|Writing	Project design	Conceived and designed the experiments	Methodology	YES
5789609	29422907	HZhang	1	Project design|Data cultivation and collection|Data analysis|Writing	Data cultivation and collection	Performed the experiments	Investigation	YES
5789609	29422907	HZhang	1	Project design|Data cultivation and collection|Data analysis|Writing	Data analysis	Analyzed the data	Formal analysis	YES
5789609	29422907	HZhang	1	Project design|Data cultivation and collection|Data analysis|Writing	Writing	Wrote the paper	-	YES
5789609	29422907	HZhao	1	Data cultivation and collection	Data cultivation and collection	Performed the experiments	Investigation	YES
5789609	29422907	LZ	1	Data cultivation and collection|Data analysis	Data cultivation and collection	Performed the experiments	Investigation	YES
5789609	29422907	LZ	1	Data cultivation and collection|Data analysis	Data analysis	Analyzed the data	Formal analysis	YES
5789609	29422907	SL	1	Data cultivation and collection|Data analysis	Data cultivation and collection	Performed the experiments	Investigation	YES
5789609	29422907	SL	1	Data cultivation and collection|Data analysis	Data analysis	Analyzed the data	Formal analysis	YES
5789609	29422907	YW	1	Project design|Data cultivation and collection|Data analysis	Project design	Conceived and designed the experiments	Methodology	YES
5789609	29422907	YW	1	Project design|Data cultivation and collection|Data analysis	Data cultivation and collection	Performed the experiments	Investigation	YES
5789609	29422907	YW	1	Project design|Data cultivation and collection|Data analysis	Data analysis	Analyzed the data	Formal analysis	YES
5789609	29422907	ZS	1	Project design|Data cultivation and collection|Data analysis|Writing	Project design	Conceived and designed the experiments	Methodology	YES
5789609	29422907	ZS	1	Project design|Data cultivation and collection|Data analysis|Writing	Data cultivation and collection	Performed the experiments	Investigation	YES
5789609	29422907	ZS	1	Project design|Data cultivation and collection|Data analysis|Writing	Data analysis	Analyzed the data	Formal analysis	YES
5789609	29422907	ZS	1	Project design|Data cultivation and collection|Data analysis|Writing	Writing	Wrote the paper	-	YES
4614737	26460133	C.Z.	1	Database design	Database design	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
4614737	26460133	F.L.	1	Database design	Database design	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
4614737	26460133	I.C.	1	Database design	Database design	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
4614737	26460133	K.K.	1	Database design	Database design	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
4614737	26460133	L.C.	1	Database design	Database design	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
4614737	26460133	M.H.	1	Database design	Database design	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
4416720	25932916	AAGP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416720	25932916	AAGP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416720	25932916	AAGP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416720	25932916	AAGP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416720	25932916	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416720	25932916	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416720	25932916	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416720	25932916	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416720	25932916	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416720	25932916	IWS	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416720	25932916	IWS	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416720	25932916	J-AT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416720	25932916	J-AT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416720	25932916	J-AT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416720	25932916	J-AT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416720	25932916	MA	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416720	25932916	MA	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416720	25932916	MH-J	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416720	25932916	MH-J	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416720	25932916	MH-J	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416720	25932916	MH-J	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416720	25932916	MPW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416720	25932916	MPW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416720	25932916	MPW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416720	25932916	MPW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5730883	29079701	HK	PLoS52	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5730883	29079701	JS	PLoS52	designed the experiments|performed the majority of the experiments|analysed the data	designed the experiments	Conceived and designed the experiments	Methodology	YES
5730883	29079701	JS	PLoS52	designed the experiments|performed the majority of the experiments|analysed the data	performed the majority of the experiments	Performed the experiments	Investigation	YES
5730883	29079701	JS	PLoS52	designed the experiments|performed the majority of the experiments|analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
5730883	29079701	MT	PLoS52	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5730883	29079701	RvS	PLoS52	commented on the manuscript	commented on the manuscript	-	-	NO
4614741	26460137	All authors	2	made contributions to the conception of this paper|gave final approval for publication	made contributions to the conception of this paper	Conceived and designed the experiments	Conceptualization	YES
4614741	26460137	All authors	2	made contributions to the conception of this paper|gave final approval for publication	gave final approval for publication	-	-	NO
4614741	26460137	D.W.	2	critically reviewed drafts for intellectual content	critically reviewed drafts for intellectual content	Wrote the paper	Writing - Original Draft	YES
4614741	26460137	E.B.	2	critically reviewed drafts for intellectual content	critically reviewed drafts for intellectual content	Wrote the paper	Writing - Original Draft	YES
4614741	26460137	E.J.M.-G.	2	critically reviewed drafts for intellectual content	critically reviewed drafts for intellectual content	Wrote the paper	Writing - Original Draft	YES
4614741	26460137	J.T.M.	2	critically reviewed drafts for intellectual content	critically reviewed drafts for intellectual content	Wrote the paper	Writing - Original Draft	YES
4614741	26460137	K.M.H.	2	critically reviewed drafts for intellectual content	critically reviewed drafts for intellectual content	Wrote the paper	Writing - Original Draft	YES
4614741	26460137	T.C.	2	critically reviewed drafts for intellectual content	critically reviewed drafts for intellectual content	Wrote the paper	Writing - Original Draft	YES
1950685	17848986	NH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1950685	17848986	NH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1950685	17848986	NH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1950685	17848986	NH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1950685	17848986	TH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1950685	17848986	TH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1950685	17848986	TH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1950685	17848986	TH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5483214	28651381	LR	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5483214	28651381	NSK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5483214	28651381	NSK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5483214	28651381	NSK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5483214	28651381	NSK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5483214	28651381	RCL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5483214	28651381	RCL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5483214	28651381	RCL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5483214	28651381	SDM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5483214	28651381	SDM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
5483214	28651381	SDM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5483214	28651381	SDM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416721	25933164	LC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416721	25933164	LC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416721	25933164	LC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416721	25933164	LC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416721	25933164	LC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416721	25933164	TP	PLoS5	Conceived and designed the experiments|Wrote the paper|Reviewed write-up of manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416721	25933164	TP	PLoS5	Conceived and designed the experiments|Wrote the paper|Reviewed write-up of manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416721	25933164	TP	PLoS5	Conceived and designed the experiments|Wrote the paper|Reviewed write-up of manuscript	Reviewed write-up of manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5789640	29422909	M-LC	PLoS52	conceived and designed the experiments|provided critical advice and suggestions on the design of experiments|wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5789640	29422909	M-LC	PLoS52	conceived and designed the experiments|provided critical advice and suggestions on the design of experiments|wrote the manuscript	provided critical advice and suggestions on the design of experiments	Conceived and designed the experiments	Methodology	YES
5789640	29422909	M-LC	PLoS52	conceived and designed the experiments|provided critical advice and suggestions on the design of experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5789640	29422909	S-CL	PLoS52	performed and analysed the isothermal titration calorimetry assays|provided critical advice and suggestions on the design of experiments|wrote the manuscript	performed and analysed the isothermal titration calorimetry assays	Performed the experiments	Investigation	YES
5789640	29422909	S-CL	PLoS52	performed and analysed the isothermal titration calorimetry assays|provided critical advice and suggestions on the design of experiments|wrote the manuscript	provided critical advice and suggestions on the design of experiments	Conceived and designed the experiments	Methodology	YES
5789640	29422909	S-CL	PLoS52	performed and analysed the isothermal titration calorimetry assays|provided critical advice and suggestions on the design of experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5789640	29422909	T-HH	PLoS52	conceived and designed the experiments|performed and analysed the isothermal titration calorimetry assays|performed and analysed the fatty acid analysis|performed all other experiments and analysed the data|wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5789640	29422909	T-HH	PLoS52	conceived and designed the experiments|performed and analysed the isothermal titration calorimetry assays|performed and analysed the fatty acid analysis|performed all other experiments and analysed the data|wrote the manuscript	performed and analysed the isothermal titration calorimetry assays	Performed the experiments	Investigation	YES
5789640	29422909	T-HH	PLoS52	conceived and designed the experiments|performed and analysed the isothermal titration calorimetry assays|performed and analysed the fatty acid analysis|performed all other experiments and analysed the data|wrote the manuscript	performed and analysed the fatty acid analysis	Performed the experiments	Investigation	YES
5789640	29422909	T-HH	PLoS52	conceived and designed the experiments|performed and analysed the isothermal titration calorimetry assays|performed and analysed the fatty acid analysis|performed all other experiments and analysed the data|wrote the manuscript	performed all other experiments and analysed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5789640	29422909	T-HH	PLoS52	conceived and designed the experiments|performed and analysed the isothermal titration calorimetry assays|performed and analysed the fatty acid analysis|performed all other experiments and analysed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5789640	29422909	Z-WY	PLoS52	provided critical advice and suggestions on the design of experiments|wrote the manuscript	provided critical advice and suggestions on the design of experiments	Conceived and designed the experiments	Methodology	YES
5789640	29422909	Z-WY	PLoS52	provided critical advice and suggestions on the design of experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6083567	30089501	ARJ	2	undertook literature review, synthesis of conclusions, and manuscript preparation|is the corresponding author for this paper	undertook literature review, synthesis of conclusions, and manuscript preparation	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
6083567	30089501	ARJ	2	undertook literature review, synthesis of conclusions, and manuscript preparation|is the corresponding author for this paper	is the corresponding author for this paper	-	-	NO
6083567	30089501	All authors	2	provided edits and final approval of the manuscript	provided edits and final approval of the manuscript	Wrote the paper	Writing - Review & Editing	YES
6083567	30089501	CMK	2	undertook literature review, synthesis of conclusions, and manuscript preparation	undertook literature review, synthesis of conclusions, and manuscript preparation	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
6083567	30089501	HAZ	2	undertook literature review, synthesis of conclusions, and manuscript preparation	undertook literature review, synthesis of conclusions, and manuscript preparation	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
6083567	30089501	JLE	2	undertook literature review, synthesis of conclusions, and manuscript preparation	undertook literature review, synthesis of conclusions, and manuscript preparation	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
6083567	30089501	PEM	2	undertook literature review, synthesis of conclusions, and manuscript preparation	undertook literature review, synthesis of conclusions, and manuscript preparation	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
6083567	30089501	PSH	2	undertook literature review, synthesis of conclusions, and manuscript preparation	undertook literature review, synthesis of conclusions, and manuscript preparation	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5730886	29133469	AFS	CRediT	investigation	investigation	Performed the experiments	Investigation	YES
5730886	29133469	CG	CRediT	investigation	investigation	Performed the experiments	Investigation	YES
5730886	29133469	DK	CRediT	funding acquisition	funding acquisition	-	Funding acquisition	YES
5730886	29133469	JLW	CRediT	investigation	investigation	Performed the experiments	Investigation	YES
5730886	29133469	SMVF	CRediT	investigation	investigation	Performed the experiments	Investigation	YES
1950686	17786208	FK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1950686	17786208	FK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1950686	17786208	FK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1950686	17786208	FK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1950686	17786208	HC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1950686	17786208	HK	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1950686	17786208	JW	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1950686	17786208	KN	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1950686	17786208	MH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1950686	17786208	NK	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1950686	17786208	NK	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1950686	17786208	SO	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1950686	17786208	SO	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1950686	17786208	UC	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1950686	17786208	YA	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5483216	28651384	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5483216	28651384	JVM	2	coordinated the statistical analysis, and critically reviewed the manuscript	coordinated the statistical analysis, and critically reviewed the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Project administration|Writing - Review & Editing	YES
5719810	29216827	All the authors	PLoS52	contributed to the analyses regarding the general genomic properties or the metabolism of energy compounds	contributed to the analyses regarding the general genomic properties or the metabolism of energy compounds	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5719810	29216827	CM	PLoS52	supervised the genomic analyses|wrote the paper	supervised the genomic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Supervision	YES
5719810	29216827	CM	PLoS52	supervised the genomic analyses|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5719810	29216827	EDB	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5719810	29216827	FI	PLoS52	initiated the project	initiated the project	Conceived and designed the experiments	Conceptualization	YES
5719810	29216827	NPP	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5719810	29216827	SL	PLoS52	initiated the project|performed their assembly	initiated the project	Conceived and designed the experiments	Conceptualization	YES
5719810	29216827	SL	PLoS52	initiated the project|performed their assembly	performed their assembly	Performed the experiments	Investigation	YES
4416722	25932915	AW	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416722	25932915	AW	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416722	25932915	DR	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416722	25932915	NC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416722	25932915	NK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416722	25932915	P. Saokhieo	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416722	25932915	P. Saokhieo	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416722	25932915	P. Saokhieo	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416722	25932915	P. Sugandhavesa	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416722	25932915	RS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416722	25932915	SC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416722	25932915	SC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416722	25932915	SC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416722	25932915	SC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416722	25932915	SS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416722	25932915	SS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4416722	25932915	SS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416722	25932915	TM	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416722	25932915	TS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416722	25932915	TS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416722	25932915	TS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416722	25932915	TS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416722	25932915	UU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416722	25932915	UU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416722	25932915	UU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416722	25932915	UU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416722	25932915	UU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4632601	26370937	I.C.	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4632601	26370937	R.C.	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4632601	26370937	W.A.	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
1950687	17726546	AP	1	The following are authors according to icmje guidelines	The following are authors according to icmje guidelines	-	-	NO
1950687	17726546	BW	1	The following are authors according to icmje guidelines	The following are authors according to icmje guidelines	-	-	NO
1950687	17726546	JP	1	The following are authors according to icmje guidelines	The following are authors according to icmje guidelines	-	-	NO
1950687	17726546	PJ	1	The following are authors according to icmje guidelines	The following are authors according to icmje guidelines	-	-	NO
1950687	17726546	TL	1	The following are authors according to icmje guidelines	The following are authors according to icmje guidelines	-	-	NO
1950687	17726546	WS	1	The following are authors according to icmje guidelines	The following are authors according to icmje guidelines	-	-	NO
6086018	30097067	AA	2	were responsible for the data collection with participants	were responsible for the data collection with participants	Performed the experiments	Investigation	YES
6086018	30097067	AC	2	conceived the study|participated in the design of the study|drafted the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
6086018	30097067	AC	2	conceived the study|participated in the design of the study|drafted the manuscript	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
6086018	30097067	AC	2	conceived the study|participated in the design of the study|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
6086018	30097067	DA	2	carried out all analysis on the dietary supplements	carried out all analysis on the dietary supplements	Performed the experiments	Investigation	YES
6086018	30097067	JS	2	were responsible for the data collection with participants	were responsible for the data collection with participants	Performed the experiments	Investigation	YES
6086018	30097067	KS	2	were responsible for the data collection with participants	were responsible for the data collection with participants	Performed the experiments	Investigation	YES
6086018	30097067	SH	2	were responsible for the data collection with participants	were responsible for the data collection with participants	Performed the experiments	Investigation	YES
6086018	30097067	TS	2	participated in the design of the study|drafted the manuscript	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
6086018	30097067	TS	2	participated in the design of the study|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4628774	26557650	Jaewan Choi	2	contributed equally to this work	contributed equally to this work	-	-	NO
4628774	26557650	Josef Flammer	2	for his historic achievements on vascular pathogenesis of glaucoma and inspirations on glaucoma specialists	for his historic achievements on vascular pathogenesis of glaucoma and inspirations on glaucoma specialists	-	-	NO
4628774	26557650	Michael S. Kook	2	contributed equally to this work	contributed equally to this work	-	-	NO
5790798	29434611	CI	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5790798	29434611	JL	PLoS52	sampled the material and contributed to sphingolipid analysis	sampled the material and contributed to sphingolipid analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5790798	29434611	MG	PLoS52	contributed to data analysis	contributed to data analysis	Analyzed the data	Formal analysis	YES
5790798	29434611	MG-J	PLoS52	conceived and supervised the study, wrote and critically revised the manuscript	conceived and supervised the study, wrote and critically revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
5790798	29434611	MG-R	PLoS52	contributed to analyze and discuss the results and prepare the manuscript	contributed to analyze and discuss the results and prepare the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5790798	29434611	MP	PLoS52	sampled the material and contributed to sphingolipid analysis	sampled the material and contributed to sphingolipid analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5790798	29434611	MP-L	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5790798	29434611	MS-G	PLoS52	contributed to analyze and discuss the results and prepare the manuscript	contributed to analyze and discuss the results and prepare the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
1950688	17786210	BA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1950688	17786210	BA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1950688	17786210	BA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1950688	17786210	BA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1950688	17786210	BM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1950688	17786210	GG	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1950688	17786210	GG	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1950688	17786210	GS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1950688	17786210	JC	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1950688	17786210	JC	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1950688	17786210	SM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1950688	17786210	YS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Wrote the first draft of the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1950688	17786210	YS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Wrote the first draft of the paper	Performed the experiments	Performed the experiments	Investigation	YES
1950688	17786210	YS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Wrote the first draft of the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1950688	17786210	YS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Wrote the first draft of the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1950688	17786210	YS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Wrote the first draft of the paper	Wrote the first draft of the paper	Wrote the paper	Writing - Original Draft	YES
6090876	30071871	HD	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6090876	30071871	HN	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6090876	30071871	KF	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
6090876	30071871	KF	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
6090876	30071871	KS	PLoS52	conceived and designed the experiments|wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6090876	30071871	KS	PLoS52	conceived and designed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6090876	30071871	TF	PLoS52	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6090876	30071871	TK	PLoS52	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6090876	30071871	YI	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
6090876	30071871	YI	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
6090876	30071871	YK	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6090876	30071871	YK	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
6090876	30071871	YK	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
6090876	30071871	YK	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5719899	29212446	All authors	2	reviewed the results and approved the final version of the manuscript	reviewed the results and approved the final version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5719899	29212446	MW	2	carried out the data collection, analyzed the data, and revised the paper	carried out the data collection, analyzed the data, and revised the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
5719899	29212446	TCG	2	carried out the data collection, analyzed the data, and revised the paper	carried out the data collection, analyzed the data, and revised the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
5719899	29212446	WT	2	carried out the data collection, analyzed the data, and revised the paper	carried out the data collection, analyzed the data, and revised the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
5790799	29434618	GW	2	analyzed the data, and wrote the manuscript	analyzed the data, and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5790799	29434618	JW	2	designed the experiments, analyzed the data and edited the manuscript	designed the experiments, analyzed the data and edited the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
5790799	29434618	JZ	2	conducted the experiments and analyzed the data	conducted the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5790799	29434618	LL	2	conducted the experiments and analyzed the data	conducted the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5790799	29434618	MY	2	designed the experiments and edited the manuscript	designed the experiments and edited the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5790799	29434618	XL	2	analyzed the data, and wrote the manuscript	analyzed the data, and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5790799	29434618	YR	2	analyzed the data and edited the manuscript	analyzed the data and edited the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5731665	29018038	CG-L	2	performed the confocal analysis experiments	performed the confocal analysis experiments	Performed the experiments	Investigation	YES
5731665	29018038	DL	2	performed and interpreted most of the experiments	performed and interpreted most of the experiments	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5731665	29018038	EA-G	2	conceived the project, designed, performed, and interpreted most of the experiments, and wrote the manuscript	conceived the project, designed, performed, and interpreted most of the experiments, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5731665	29018038	EAS	2	conceived the project, interpreted most of the experiments, and wrote the manuscript	conceived the project, interpreted most of the experiments, and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
5731665	29018038	FPM	2	performed the electron microscopy studies	performed the electron microscopy studies	Performed the experiments	Investigation	YES
5731665	29018038	GDP	2	performed most of the lipidomics analysis	performed most of the lipidomics analysis	Performed the experiments	Investigation	YES
5731665	29018038	GSP	2	performed the electron microscopy studies	performed the electron microscopy studies	Performed the experiments	Investigation	YES
5731665	29018038	JAE	2	performed the supercomplexes analysis	performed the supercomplexes analysis	Performed the experiments	Investigation	YES
5731665	29018038	JM	2	performed and interpreted most of the experiments	performed and interpreted most of the experiments	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5731665	29018038	KRV	2	provided laboratory support	provided laboratory support	-	-	NO
5731665	29018038	MFM	2	provided the ps1-ki m146v mice	provided the ps1-ki m146v mice	Contributed reagents/materials/analysis tools	Resources	YES
5731665	29018038	MP	2	performed and interpreted most of the experiments	performed and interpreted most of the experiments	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5731665	29018038	RA-P	2	performed the supercomplexes analysis	performed the supercomplexes analysis	Performed the experiments	Investigation	YES
5731665	29018038	RBC	2	performed most of the lipidomics analysis	performed most of the lipidomics analysis	Performed the experiments	Investigation	YES
5731665	29018038	RRA	2	performed and interpreted most of the experiments	performed and interpreted most of the experiments	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5731665	29018038	YX	2	performed most of the lipidomics analysis	performed most of the lipidomics analysis	Performed the experiments	Investigation	YES
5731665	29018038	ZZF	2	performed the electron microscopy studies	performed the electron microscopy studies	Performed the experiments	Investigation	YES
4416724	25933090	AA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416724	25933090	AA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416724	25933090	AA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416724	25933090	AA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416724	25933090	MO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416724	25933090	MO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416724	25933090	MO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416724	25933090	MO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416724	25933090	SJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416724	25933090	SJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416724	25933090	SJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416724	25933090	SJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4632607	26370943	A.J.F.E.	2	contributed to the conception and design of the study and analysed and interpreted data|acquired data, and all authors drafted and revised the article	contributed to the conception and design of the study and analysed and interpreted data	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Methodology|Resources	YES
4632607	26370943	A.J.F.E.	2	contributed to the conception and design of the study and analysed and interpreted data|acquired data, and all authors drafted and revised the article	acquired data, and all authors drafted and revised the article	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
4632607	26370943	J.B.	2	contributed to the conception and design of the study and analysed and interpreted data|acquired data, and all authors drafted and revised the article	contributed to the conception and design of the study and analysed and interpreted data	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Methodology|Resources	YES
4632607	26370943	J.B.	2	contributed to the conception and design of the study and analysed and interpreted data|acquired data, and all authors drafted and revised the article	acquired data, and all authors drafted and revised the article	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
4632607	26370943	W.V.	2	contributed to the conception and design of the study and analysed and interpreted data	contributed to the conception and design of the study and analysed and interpreted data	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Methodology|Resources	YES
1950689	17786189	DB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Wrote the first draft of the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1950689	17786189	DB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Wrote the first draft of the paper	Performed the experiments	Performed the experiments	Investigation	YES
1950689	17786189	DB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Wrote the first draft of the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1950689	17786189	DB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Wrote the first draft of the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1950689	17786189	DB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Wrote the first draft of the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1950689	17786189	DB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Wrote the first draft of the paper	Wrote the first draft of the paper	Wrote the paper	Writing - Original Draft	YES
1950689	17786189	RK	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1950689	17786189	RK	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5483222	28651382	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5483222	28651382	MP	2	designed the study, coordinated the work and wrote the draft of the manuscript	designed the study, coordinated the work and wrote the draft of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft	YES
5721659	29216844	CF	PLoS52	collected samples|collected the data|analyzed the data|wrote and revised the manuscript|performed the study, participated in the data analysis and wrote the manuscript	collected samples	Performed the experiments	Investigation	YES
5721659	29216844	CF	PLoS52	collected samples|collected the data|analyzed the data|wrote and revised the manuscript|performed the study, participated in the data analysis and wrote the manuscript	collected the data	Performed the experiments	Investigation	YES
5721659	29216844	CF	PLoS52	collected samples|collected the data|analyzed the data|wrote and revised the manuscript|performed the study, participated in the data analysis and wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5721659	29216844	CF	PLoS52	collected samples|collected the data|analyzed the data|wrote and revised the manuscript|performed the study, participated in the data analysis and wrote the manuscript	wrote and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5721659	29216844	CF	PLoS52	collected samples|collected the data|analyzed the data|wrote and revised the manuscript|performed the study, participated in the data analysis and wrote the manuscript	performed the study, participated in the data analysis and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5721659	29216844	DL	PLoS52	designed the research|collected samples|wrote and revised the manuscript|designed the research and revised the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
5721659	29216844	DL	PLoS52	designed the research|collected samples|wrote and revised the manuscript|designed the research and revised the manuscript	collected samples	Performed the experiments	Investigation	YES
5721659	29216844	DL	PLoS52	designed the research|collected samples|wrote and revised the manuscript|designed the research and revised the manuscript	wrote and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5721659	29216844	DL	PLoS52	designed the research|collected samples|wrote and revised the manuscript|designed the research and revised the manuscript	designed the research and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5721659	29216844	HL	PLoS52	collected the data|participated in the data analysis	collected the data	Performed the experiments	Investigation	YES
5721659	29216844	HL	PLoS52	collected the data|participated in the data analysis	participated in the data analysis	Analyzed the data	Formal analysis	YES
5721659	29216844	JY	PLoS52	collected the data|participated in the dna sequencing	collected the data	Performed the experiments	Investigation	YES
5721659	29216844	JY	PLoS52	collected the data|participated in the dna sequencing	participated in the dna sequencing	Performed the experiments	Investigation	YES
5721659	29216844	LG	PLoS52	designed the research|collected samples|wrote and revised the manuscript|designed the research, collected study materials and revised the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
5721659	29216844	LG	PLoS52	designed the research|collected samples|wrote and revised the manuscript|designed the research, collected study materials and revised the manuscript	collected samples	Performed the experiments	Investigation	YES
5721659	29216844	LG	PLoS52	designed the research|collected samples|wrote and revised the manuscript|designed the research, collected study materials and revised the manuscript	wrote and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5721659	29216844	LG	PLoS52	designed the research|collected samples|wrote and revised the manuscript|designed the research, collected study materials and revised the manuscript	designed the research, collected study materials and revised the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
5721659	29216844	PM	PLoS52	analyzed the data|wrote and revised the manuscript|participated in the data analysis and manuscript revising	analyzed the data	Analyzed the data	Formal analysis	YES
5721659	29216844	PM	PLoS52	analyzed the data|wrote and revised the manuscript|participated in the data analysis and manuscript revising	wrote and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5721659	29216844	PM	PLoS52	analyzed the data|wrote and revised the manuscript|participated in the data analysis and manuscript revising	participated in the data analysis and manuscript revising	Analyzed the data	Formal analysis	YES
5721659	29216844	RM	PLoS52	wrote and revised the manuscript|revised the manuscript	wrote and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5721659	29216844	RM	PLoS52	wrote and revised the manuscript|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5721659	29216844	TZ	PLoS52	collected samples|participated in samples collection	collected samples	Performed the experiments	Investigation	YES
5721659	29216844	TZ	PLoS52	collected samples|participated in samples collection	participated in samples collection	Performed the experiments	Investigation	YES
4628956	26558256	Chiara Posarelli	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
4628956	26558256	Michele Figus	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
4416725	25933357	CS	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416725	25933357	CY	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416725	25933357	FL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416725	25933357	FZ	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4416725	25933357	FZ	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416725	25933357	HC	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4416725	25933357	HC	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4416725	25933357	HC	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416725	25933357	NS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416725	25933357	NS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416725	25933357	NW	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416725	25933357	NW	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416725	25933357	PL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416725	25933357	SY	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416725	25933357	XY	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416725	25933357	XY	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416725	25933357	XY	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416725	25933357	XZ	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416725	25933357	YL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416725	25933357	YL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416725	25933357	YL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416725	25933357	YL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416725	25933357	YS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1950690	17786211	IK	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1950690	17786211	IK	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1950690	17786211	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1950690	17786211	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1950690	17786211	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1950690	17786211	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1950690	17786211	KM	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1950690	17786211	KM	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1950690	17786211	MS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1950690	17786211	MS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1950690	17786211	MS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5483225	28651383	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5483225	28651383	GC	2	assisted to carry out experiments	assisted to carry out experiments	Performed the experiments	Investigation	YES
5483225	28651383	HLT	2	assisted to carry out experiments	assisted to carry out experiments	Performed the experiments	Investigation	YES
5483225	28651383	LW	2	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5483225	28651383	TH	2	planned and carried out the experiments, analyzed the data and wrote the manuscript	planned and carried out the experiments, analyzed the data and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
5483225	28651383	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5483225	28651383	ZQW	2	participated in the data analysis and finalized the manuscript	participated in the data analysis and finalized the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5790801	29434616	All	2	the co-authors contributed to the writing of the manuscript	the co-authors contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5790801	29434616	MFSG	2	designed the synthesis and wrote the manuscript	designed the synthesis and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
4633848	26503685	A.R.	2	wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
4633848	26503685	K.M.C.	2	wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
4633848	26503685	L.G.	2	wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
4633848	26503685	R.W.	2	wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
5753033	29141912	DAF	2	supervised the project and wrote the manuscript	supervised the project and wrote the manuscript	Wrote the paper	Supervision|Writing - Original Draft	YES
5753033	29141912	NPF	2	micropatterns by fluorescence fluctuation spectroscopy	micropatterns by fluorescence fluctuation spectroscopy	Performed the experiments	Investigation	YES
5753033	29141912	OA	2	performed and analyzed the analytical ultracentrifugation experiments and contributed important early observations that initiated the project	performed and analyzed the analytical ultracentrifugation experiments and contributed important early observations that initiated the project	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation	YES
5753033	29141912	PB	2	prepared all reagents, designed and performed experiments, analyzed data and wrote the manuscript	prepared all reagents, designed and performed experiments, analyzed data and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
5753033	29141912	RDM	2	supervised the project and wrote the manuscript	supervised the project and wrote the manuscript	Wrote the paper	Supervision|Writing - Original Draft	YES
5753033	29141912	SDH	2	prepared all reagents, designed and performed experiments, analyzed data and wrote the manuscript	prepared all reagents, designed and performed experiments, analyzed data and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
4628957	26558257	Chunqin Zheng	PLoS52	contributed to the study design|performed the research and conducted the data analysis|wrote the paper|contributed equally to this work	contributed to the study design	Conceived and designed the experiments	Methodology	YES
4628957	26558257	Chunqin Zheng	PLoS52	contributed to the study design|performed the research and conducted the data analysis|wrote the paper|contributed equally to this work	performed the research and conducted the data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4628957	26558257	Chunqin Zheng	PLoS52	contributed to the study design|performed the research and conducted the data analysis|wrote the paper|contributed equally to this work	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4628957	26558257	Chunqin Zheng	PLoS52	contributed to the study design|performed the research and conducted the data analysis|wrote the paper|contributed equally to this work	contributed equally to this work	-	-	NO
4628957	26558257	Hailong Zhao	PLoS52	performed the research and conducted the data analysis|wrote the paper|contributed equally to this work	performed the research and conducted the data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4628957	26558257	Hailong Zhao	PLoS52	performed the research and conducted the data analysis|wrote the paper|contributed equally to this work	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4628957	26558257	Hailong Zhao	PLoS52	performed the research and conducted the data analysis|wrote the paper|contributed equally to this work	contributed equally to this work	-	-	NO
4628957	26558257	Hongjuan Cui	PLoS52	contributed to the study design	contributed to the study design	Conceived and designed the experiments	Methodology	YES
5725879	29228896	A. All	2	authors read, edited and approved the final manuscript	authors read, edited and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5725879	29228896	AM	2	participated in the design of the study	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
5725879	29228896	CT	2	participated in the design of the study|conceived the study	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
5725879	29228896	CT	2	participated in the design of the study|conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5725879	29228896	EA	2	participated in the design of the study|conceived the study	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
5725879	29228896	EA	2	participated in the design of the study|conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5725879	29228896	JCMJr	2	participated in the design of the study	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
5725879	29228896	JL	2	participated in the design of the study|conceived the study	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
5725879	29228896	JL	2	participated in the design of the study|conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4416726	25932640	GZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416726	25932640	GZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416726	25932640	GZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416726	25932640	GZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416726	25932640	JW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416726	25932640	JW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416726	25932640	JW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416726	25932640	JY	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4416726	25932640	JY	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4416726	25932640	JY	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416726	25932640	MY	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416726	25932640	MY	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4416726	25932640	MY	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416726	25932640	RH	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4416726	25932640	RH	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416726	25932640	WG	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4416726	25932640	WG	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416726	25932640	XW	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416726	25932640	XW	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416726	25932640	XW	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416726	25932640	XW	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416726	25932640	YY	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416726	25932640	YY	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416726	25932640	ZZ	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416726	25932640	ZZ	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1950738	17726541	DG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1950738	17726541	DG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1950738	17726541	DG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1950738	17726541	SC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1950738	17726541	SC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1950738	17726541	SC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1950738	17726541	SC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5484652	28655214	All	2	datasets on which the conclusions of the manuscript rely are presented in the main paper	datasets on which the conclusions of the manuscript rely are presented in the main paper	-	-	NO
5484652	28655214	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5484652	28655214	LF	2	designed whole experiment|helped on the paperwork	designed whole experiment	Conceived and designed the experiments	Methodology	YES
5484652	28655214	LF	2	designed whole experiment|helped on the paperwork	helped on the paperwork	-	-	NO
5484652	28655214	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5484652	28655214	XS	2	helped to carry the experiment|contributed data analysis	helped to carry the experiment	Performed the experiments	Investigation	YES
5484652	28655214	XS	2	helped to carry the experiment|contributed data analysis	contributed data analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5484652	28655214	XY	2	designed whole experiment|contributed data analysis	designed whole experiment	Conceived and designed the experiments	Methodology	YES
5484652	28655214	XY	2	designed whole experiment|contributed data analysis	contributed data analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5484652	28655214	YW	2	helped to carry the experiment	helped to carry the experiment	Performed the experiments	Investigation	YES
6090881	30068354	ASR	2	all contributed to the development of selected parts of the manuscript	all contributed to the development of selected parts of the manuscript	Wrote the paper	Writing - Original Draft	YES
6090881	30068354	All authors	2	reviewed and approved the final draft of this manuscript	reviewed and approved the final draft of this manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6090881	30068354	CDW	2	provided substantial support in revising and drafting several sections	provided substantial support in revising and drafting several sections	Wrote the paper	Writing - Original Draft	YES
6090881	30068354	CMK	2	contributed most of the content and served as senior editors on the paper	contributed most of the content and served as senior editors on the paper	Wrote the paper	Writing - Review & Editing	YES
6090881	30068354	EG	2	all contributed to the development of selected parts of the manuscript	all contributed to the development of selected parts of the manuscript	Wrote the paper	Writing - Original Draft	YES
6090881	30068354	JND	2	all contributed to the development of selected parts of the manuscript	all contributed to the development of selected parts of the manuscript	Wrote the paper	Writing - Original Draft	YES
6090881	30068354	LML	2	all contributed to the development of selected parts of the manuscript	all contributed to the development of selected parts of the manuscript	Wrote the paper	Writing - Original Draft	YES
6090881	30068354	MBC	2	all contributed to the development of selected parts of the manuscript	all contributed to the development of selected parts of the manuscript	Wrote the paper	Writing - Original Draft	YES
6090881	30068354	MDR	2	provided substantial support in revising and drafting several sections	provided substantial support in revising and drafting several sections	Wrote the paper	Writing - Original Draft	YES
6090881	30068354	MG	2	all contributed to the development of selected parts of the manuscript	all contributed to the development of selected parts of the manuscript	Wrote the paper	Writing - Original Draft	YES
6090881	30068354	RBK	2	contributed most of the content and served as senior editors on the paper|is the corresponding author	contributed most of the content and served as senior editors on the paper	Wrote the paper	Writing - Review & Editing	YES
6090881	30068354	RBK	2	contributed most of the content and served as senior editors on the paper|is the corresponding author	is the corresponding author	-	-	NO
6090881	30068354	RC	2	all contributed to the development of selected parts of the manuscript	all contributed to the development of selected parts of the manuscript	Wrote the paper	Writing - Original Draft	YES
6090881	30068354	RJ	2	all contributed to the development of selected parts of the manuscript	all contributed to the development of selected parts of the manuscript	Wrote the paper	Writing - Original Draft	YES
6090881	30068354	RW	2	all contributed to the development of selected parts of the manuscript	all contributed to the development of selected parts of the manuscript	Wrote the paper	Writing - Original Draft	YES
6090881	30068354	SMK	2	all contributed to the development of selected parts of the manuscript	all contributed to the development of selected parts of the manuscript	Wrote the paper	Writing - Original Draft	YES
5790987	29434610	LL	PLoS5	Conceived and designed the study|Performed the experiments|Wrote the manuscript|Data analysis	Conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5790987	29434610	LL	PLoS5	Conceived and designed the study|Performed the experiments|Wrote the manuscript|Data analysis	Performed the experiments	Performed the experiments	Investigation	YES
5790987	29434610	LL	PLoS5	Conceived and designed the study|Performed the experiments|Wrote the manuscript|Data analysis	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5790987	29434610	LL	PLoS5	Conceived and designed the study|Performed the experiments|Wrote the manuscript|Data analysis	Data analysis	Analyzed the data	Formal analysis	YES
5790987	29434610	LW	PLoS5	Performed the experiments|Data analysis	Performed the experiments	Performed the experiments	Investigation	YES
5790987	29434610	LW	PLoS5	Performed the experiments|Data analysis	Data analysis	Analyzed the data	Formal analysis	YES
5790987	29434610	XH	PLoS5	Conceived and designed the study|Performed the experiments|Data analysis	Conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5790987	29434610	XH	PLoS5	Conceived and designed the study|Performed the experiments|Data analysis	Performed the experiments	Performed the experiments	Investigation	YES
5790987	29434610	XH	PLoS5	Conceived and designed the study|Performed the experiments|Data analysis	Data analysis	Analyzed the data	Formal analysis	YES
5790987	29434610	ZG	PLoS5	Conceived and designed the study	Conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4633849	26503686	J.H.	2	conceived the basic idea and wrote the first draft|checked the models and all three authors revised/improved the manuscript	conceived the basic idea and wrote the first draft	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4633849	26503686	J.H.	2	conceived the basic idea and wrote the first draft|checked the models and all three authors revised/improved the manuscript	checked the models and all three authors revised/improved the manuscript	Performed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
4633849	26503686	R.B.	2	checked the models and all three authors revised/improved the manuscript|checked the models and all three authors revised/improved the manuscript	checked the models and all three authors revised/improved the manuscript	Performed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
4633849	26503686	R.B.	2	checked the models and all three authors revised/improved the manuscript|checked the models and all three authors revised/improved the manuscript	checked the models and all three authors revised/improved the manuscript	Performed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
4416727	25932635	DA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416727	25932635	DA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416727	25932635	DA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416727	25932635	M-TH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416727	25932635	M-TH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416727	25932635	M-TH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416727	25932635	YH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416727	25932635	YH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416727	25932635	YH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4628958	26558260	Jing-Fang Hong	2	contributed equally to this work	contributed equally to this work	-	-	NO
4628958	26558260	Ying-Fang Song	2	contributed equally to this work	contributed equally to this work	-	-	NO
5753034	29084722	GJT	2	designed experiments|wrote the manuscript|analysed data	designed experiments	Conceived and designed the experiments	Methodology	YES
5753034	29084722	GJT	2	designed experiments|wrote the manuscript|analysed data	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5753034	29084722	GJT	2	designed experiments|wrote the manuscript|analysed data	analysed data	Analyzed the data	Formal analysis	YES
5753034	29084722	IAT	2	designed, performed experiments and analysed dntp data	designed, performed experiments and analysed dntp data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5753034	29084722	PM	2	designed experiments|wrote the manuscript|performed experiments|analysed data	designed experiments	Conceived and designed the experiments	Methodology	YES
5753034	29084722	PM	2	designed experiments|wrote the manuscript|performed experiments|analysed data	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5753034	29084722	PM	2	designed experiments|wrote the manuscript|performed experiments|analysed data	performed experiments	Performed the experiments	Investigation	YES
5753034	29084722	PM	2	designed experiments|wrote the manuscript|performed experiments|analysed data	analysed data	Analyzed the data	Formal analysis	YES
5753034	29084722	RKG	2	designed experiments|wrote the manuscript|analysed data	designed experiments	Conceived and designed the experiments	Methodology	YES
5753034	29084722	RKG	2	designed experiments|wrote the manuscript|analysed data	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5753034	29084722	RKG	2	designed experiments|wrote the manuscript|analysed data	analysed data	Analyzed the data	Formal analysis	YES
5753034	29084722	SJC	2	designed, performed experiments and analysed dntp data	designed, performed experiments and analysed dntp data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5725899	29228904	CGL	2	analysed, interpreted data and revised the manuscript	analysed, interpreted data and revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5725899	29228904	JJV	2	performed the experiments and revised the manuscript	performed the experiments and revised the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5725899	29228904	MAH	2	conceived and designed the experiment|performed the experiments and revised the manuscript|analysed, interpreted data and revised the manuscript|drafted the original manuscript	conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5725899	29228904	MAH	2	conceived and designed the experiment|performed the experiments and revised the manuscript|analysed, interpreted data and revised the manuscript|drafted the original manuscript	performed the experiments and revised the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5725899	29228904	MAH	2	conceived and designed the experiment|performed the experiments and revised the manuscript|analysed, interpreted data and revised the manuscript|drafted the original manuscript	analysed, interpreted data and revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5725899	29228904	MAH	2	conceived and designed the experiment|performed the experiments and revised the manuscript|analysed, interpreted data and revised the manuscript|drafted the original manuscript	drafted the original manuscript	Wrote the paper	Writing - Original Draft	YES
5725899	29228904	MM	2	conceived and designed the experiment	conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5725899	29228904	TNS	2	conceived and designed the experiment	conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5484653	28655215	All authors	2	contributed to the design of the experiment|read and approved the final manuscript	contributed to the design of the experiment	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5484653	28655215	All authors	2	contributed to the design of the experiment|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5484653	28655215	MA	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5484653	28655215	MRS	2	participated in the design of the study, supervised the research work	participated in the design of the study, supervised the research work	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Supervision	YES
5484653	28655215	SER	2	designed and supervised the research study	designed and supervised the research study	Conceived and designed the experiments	Methodology|Supervision	YES
5484653	28655215	SR	2	designed and supervised the research study	designed and supervised the research study	Conceived and designed the experiments	Methodology|Supervision	YES
1950790	17786212	EE	PLoS5	Conceived and designed the experiments|Analyzed the data|Critically revised the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1950790	17786212	EE	PLoS5	Conceived and designed the experiments|Analyzed the data|Critically revised the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
1950790	17786212	EE	PLoS5	Conceived and designed the experiments|Analyzed the data|Critically revised the manuscript	Critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
1950790	17786212	JI	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1950790	17786212	JI	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1950790	17786212	JI	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1950790	17786212	NP	PLoS5	Conceived and designed the experiments|Analyzed the data|Critically revised the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1950790	17786212	NP	PLoS5	Conceived and designed the experiments|Analyzed the data|Critically revised the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
1950790	17786212	NP	PLoS5	Conceived and designed the experiments|Analyzed the data|Critically revised the manuscript	Critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4633994	26416676	A.S.	2	coordinated the study|wrote the manuscript	coordinated the study	-	Project administration	YES
4633994	26416676	A.S.	2	coordinated the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4633994	26416676	All authors	2	approve the submission	approve the submission	-	-	NO
4633994	26416676	M.R.	2	designed the study, conducted the experiments and analysed the results|wrote the manuscript	designed the study, conducted the experiments and analysed the results	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
4633994	26416676	M.R.	2	designed the study, conducted the experiments and analysed the results|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4633994	26416676	N.B.	2	analysed the grafting experiments	analysed the grafting experiments	-	-	NO
6102834	30124167	All authors	2	helped with the draft of the manuscript, read and approved the final paper	helped with the draft of the manuscript, read and approved the final paper	Wrote the paper	Writing - Original Draft	YES
6102834	30124167	JA	2	performed the data collection	performed the data collection	Performed the experiments	Investigation	YES
6102834	30124167	JT	2	performed the data collection|performed the statistical analysis	performed the data collection	Performed the experiments	Investigation	YES
6102834	30124167	JT	2	performed the data collection|performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
6102834	30124167	RK	2	performed the data collection	performed the data collection	Performed the experiments	Investigation	YES
6102834	30124167	SK	2	performed the data collection	performed the data collection	Performed the experiments	Investigation	YES
5790996	29434613	HY	7	managed the materials	managed the materials	-	-	NO
5790996	29434613	JY	7	designed the research experiments|performed the phenotyping|analyzed the data and drafted the manuscript	designed the research experiments	Conceived and designed the experiments	Methodology	YES
5790996	29434613	JY	7	designed the research experiments|performed the phenotyping|analyzed the data and drafted the manuscript	performed the phenotyping	Performed the experiments	Investigation	YES
5790996	29434613	JY	7	designed the research experiments|performed the phenotyping|analyzed the data and drafted the manuscript	analyzed the data and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5790996	29434613	QX	7	carried out the genetic studies	carried out the genetic studies	Performed the experiments	Investigation	YES
5790996	29434613	ShaW	7	performed the phenotyping	performed the phenotyping	Performed the experiments	Investigation	YES
5790996	29434613	ShuW	7	carried out the genetic studies|helped to revise the manuscript	carried out the genetic studies	Performed the experiments	Investigation	YES
5790996	29434613	ShuW	7	carried out the genetic studies|helped to revise the manuscript	helped to revise the manuscript	Wrote the paper	Writing - Review & Editing	YES
5790996	29434613	XN	7	designed the research experiments|analyzed the data and drafted the manuscript	designed the research experiments	Conceived and designed the experiments	Methodology	YES
5790996	29434613	XN	7	designed the research experiments|analyzed the data and drafted the manuscript	analyzed the data and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5790996	29434613	XW	7	designed the research experiments|designed the overall project	designed the research experiments	Conceived and designed the experiments	Methodology	YES
5790996	29434613	XW	7	designed the research experiments|designed the overall project	designed the overall project	Conceived and designed the experiments	Methodology	YES
5790996	29434613	XY	7	managed the materials	managed the materials	-	-	NO
5790996	29434613	YF	7	performed the phenotyping|carried out the genetic studies|helped to revise the manuscript	performed the phenotyping	Performed the experiments	Investigation	YES
5790996	29434613	YF	7	performed the phenotyping|carried out the genetic studies|helped to revise the manuscript	carried out the genetic studies	Performed the experiments	Investigation	YES
5790996	29434613	YF	7	performed the phenotyping|carried out the genetic studies|helped to revise the manuscript	helped to revise the manuscript	Wrote the paper	Writing - Review & Editing	YES
5790996	29434613	YW	7	managed the materials	managed the materials	-	-	NO
1950791	17786209	BP	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1950791	17786209	BP	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1950791	17786209	DK	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1950791	17786209	DK	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1950791	17786209	KN	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1950791	17786209	KN	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1950791	17786209	MB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1950791	17786209	MM	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1950791	17786209	PZ	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1950791	17786209	PZ	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1950791	17786209	SM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1950791	17786209	SM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1950791	17786209	SM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1950791	17786209	SR	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1950791	17786209	SR	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1950791	17786209	VM	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1950791	17786209	VM	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416729	25933213	HY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416729	25933213	HY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416729	25933213	HY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416729	25933213	HY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416729	25933213	KN	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416729	25933213	KN	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416729	25933213	KN	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416729	25933213	TF	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416729	25933213	TM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416729	25933213	TM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416729	25933213	TM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416729	25933213	TM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416729	25933213	YF	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416729	25933213	YF	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416729	25933213	YF	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5753035	29146773	All authors	2	commented on and refined the manuscript	commented on and refined the manuscript	-	-	NO
5753035	29146773	All other authors	2	designed and performed the experiments from figs 5 , 6 7 8 9 10 11 12 13 14 15	designed and performed the experiments from figs 5 , 6 7 8 9 10 11 12 13 14 15	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5753035	29146773	KNR	2	designed the experiments|wrote the initial manuscript draft	designed the experiments	Conceived and designed the experiments	Methodology	YES
5753035	29146773	KNR	2	designed the experiments|wrote the initial manuscript draft	wrote the initial manuscript draft	Wrote the paper	Writing - Original Draft	YES
5753035	29146773	NHR	2	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5753035	29146773	SOR	2	designed the experiments|wrote the initial manuscript draft|supervised the project	designed the experiments	Conceived and designed the experiments	Methodology	YES
5753035	29146773	SOR	2	designed the experiments|wrote the initial manuscript draft|supervised the project	wrote the initial manuscript draft	Wrote the paper	Writing - Original Draft	YES
5753035	29146773	SOR	2	designed the experiments|wrote the initial manuscript draft|supervised the project	supervised the project	-	Supervision	YES
5727874	29233099	APA	PLoS52	participated in the analyses and provided consultation	participated in the analyses and provided consultation	Analyzed the data	Formal analysis	YES
5727874	29233099	CRY	PLoS52	designed the experiments and supervised the research|wrote the paper	designed the experiments and supervised the research	Conceived and designed the experiments	Methodology|Supervision	YES
5727874	29233099	CRY	PLoS52	designed the experiments and supervised the research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5727874	29233099	KD	PLoS52	performed bioinformatics analyses	performed bioinformatics analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5727874	29233099	LM	PLoS52	designed the experiments and supervised the research|performed the experiments|wrote the paper	designed the experiments and supervised the research	Conceived and designed the experiments	Methodology|Supervision	YES
5727874	29233099	LM	PLoS52	designed the experiments and supervised the research|performed the experiments|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5727874	29233099	LM	PLoS52	designed the experiments and supervised the research|performed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5727874	29233099	VD	PLoS52	performed bioinformatics analyses|wrote the paper	performed bioinformatics analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5727874	29233099	VD	PLoS52	performed bioinformatics analyses|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5484655	28655218	AJF	2	designed the experiments|conducted the experiments|evaluated the results and drafted the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5484655	28655218	AJF	2	designed the experiments|conducted the experiments|evaluated the results and drafted the manuscript	conducted the experiments	Performed the experiments	Investigation	YES
5484655	28655218	AJF	2	designed the experiments|conducted the experiments|evaluated the results and drafted the manuscript	evaluated the results and drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5484655	28655218	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5484655	28655218	CCY	2	conducted the experiments	conducted the experiments	Performed the experiments	Investigation	YES
5484655	28655218	JHW	2	performed the field observation and collected samples|designed the experiments|revised the manuscript	performed the field observation and collected samples	Performed the experiments	Investigation	YES
5484655	28655218	JHW	2	performed the field observation and collected samples|designed the experiments|revised the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5484655	28655218	JHW	2	performed the field observation and collected samples|designed the experiments|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5484655	28655218	JPY	2	performed the field observation and collected samples	performed the field observation and collected samples	Performed the experiments	Investigation	YES
5484655	28655218	QZ	2	performed the field observation and collected samples	performed the field observation and collected samples	Performed the experiments	Investigation	YES
5484655	28655218	XMX	2	conducted the experiments	conducted the experiments	Performed the experiments	Investigation	YES
5484655	28655218	XX	2	conducted the experiments	conducted the experiments	Performed the experiments	Investigation	YES
5484655	28655218	YHH	2	designed the experiments|evaluated the results and drafted the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5484655	28655218	YHH	2	designed the experiments|evaluated the results and drafted the manuscript	evaluated the results and drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
6270655	24786687	A.I.	2	performed the synthesis of mixed and association complexes|have analyzed the data from high performance liquid chromatography coupled to mass spectrometry|performed and analyzed the circular dichroism experiments	performed the synthesis of mixed and association complexes	Performed the experiments	Investigation	YES
6270655	24786687	A.I.	2	performed the synthesis of mixed and association complexes|have analyzed the data from high performance liquid chromatography coupled to mass spectrometry|performed and analyzed the circular dichroism experiments	have analyzed the data from high performance liquid chromatography coupled to mass spectrometry	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270655	24786687	A.I.	2	performed the synthesis of mixed and association complexes|have analyzed the data from high performance liquid chromatography coupled to mass spectrometry|performed and analyzed the circular dichroism experiments	performed and analyzed the circular dichroism experiments	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270655	24786687	A.P.S.A.	2	have analyzed the data from high performance liquid chromatography coupled to mass spectrometry	have analyzed the data from high performance liquid chromatography coupled to mass spectrometry	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270655	24786687	C.D.	2	have designed the whole study and written and modified the paper	have designed the whole study and written and modified the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft|Writing - Review & Editing	YES
6270655	24786687	F.F.	2	have designed the whole study and written and modified the paper	have designed the whole study and written and modified the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft|Writing - Review & Editing	YES
6270655	24786687	F.R.F.	2	performed and analyzed the circular dichroism experiments	performed and analyzed the circular dichroism experiments	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270655	24786687	W.A.F.	2	performed the synthesis of mixed and association complexes	performed the synthesis of mixed and association complexes	Performed the experiments	Investigation	YES
1950908	17726524	CH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Contributed to the immunohistochemical analysis of distinct interneuronal subsets in the embryonic cortex	Performed the experiments	Performed the experiments	Investigation	YES
1950908	17726524	CH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Contributed to the immunohistochemical analysis of distinct interneuronal subsets in the embryonic cortex	Analyzed the data	Analyzed the data	Formal analysis	YES
1950908	17726524	CH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Contributed to the immunohistochemical analysis of distinct interneuronal subsets in the embryonic cortex	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1950908	17726524	CH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Contributed to the immunohistochemical analysis of distinct interneuronal subsets in the embryonic cortex	Contributed to the immunohistochemical analysis of distinct interneuronal subsets in the embryonic cortex	Performed the experiments	Investigation	YES
1950908	17726524	EA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Contributed to data analysis|Contributed to writing of the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1950908	17726524	EA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Contributed to data analysis|Contributed to writing of the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
1950908	17726524	EA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Contributed to data analysis|Contributed to writing of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
1950908	17726524	EA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Contributed to data analysis|Contributed to writing of the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1950908	17726524	EA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Contributed to data analysis|Contributed to writing of the manuscript	Contributed to data analysis	Analyzed the data	Formal analysis	YES
1950908	17726524	EA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Contributed to data analysis|Contributed to writing of the manuscript	Contributed to writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
1950908	17726524	HG	PLoS5	Wrote the paper|Collaboratively worked with the first author on the in vivo two-photon imaging of interneuronal migration in living embryos	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1950908	17726524	HG	PLoS5	Wrote the paper|Collaboratively worked with the first author on the in vivo two-photon imaging of interneuronal migration in living embryos	Collaboratively worked with the first author on the in vivo two-photon imaging of interneuronal migration in living embryos	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
1950908	17726524	HW	PLoS5	Helped to analyze migration patterns of distinct interneuronal subsets in the embryonic cortex	Helped to analyze migration patterns of distinct interneuronal subsets in the embryonic cortex	Analyzed the data	Formal analysis	YES
1950908	17726524	KC	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to the writing of the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1950908	17726524	KC	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to the writing of the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1950908	17726524	KC	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to the writing of the manuscript	Contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
1950908	17726524	TG	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1950908	17726524	TG	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1950908	17726524	YY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Conducted most of the experiments|Wrote the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1950908	17726524	YY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Conducted most of the experiments|Wrote the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
1950908	17726524	YY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Conducted most of the experiments|Wrote the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
1950908	17726524	YY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Conducted most of the experiments|Wrote the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1950908	17726524	YY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Conducted most of the experiments|Wrote the manuscript	Conducted most of the experiments	Performed the experiments	Investigation	YES
1950908	17726524	YY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Conducted most of the experiments|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6137928	30217199	SH	2	did all of the statistical analyses and wrote the paper	did all of the statistical analyses and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4634004	26416686	All authors	2	reviewed and approved the final manuscript	reviewed and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4634004	26416686	J.H.	2	researched and wrote the section on cell-technology classification, reviewed and approved the final manuscript	researched and wrote the section on cell-technology classification, reviewed and approved the final manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
4634004	26416686	N.M.	2	researched and wrote the sections on clinical trials and regulation of cell therapies, reviewed and approved the final manuscript	researched and wrote the sections on clinical trials and regulation of cell therapies, reviewed and approved the final manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
4634004	26416686	P.K.	2	researched and wrote the section on reimbursement of cell therapies, reviewed and approved the final manuscript	researched and wrote the section on reimbursement of cell therapies, reviewed and approved the final manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
4634004	26416686	S.W.	2	researched and wrote the section on manufacturing, reviewed and approved the final manuscript	researched and wrote the section on manufacturing, reviewed and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5791008	29434617	AR	2	designed the experiments|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5791008	29434617	AR	2	designed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5791008	29434617	HR	2	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5791008	29434617	JJ	2	designed gfp-hfbi fusion system	designed gfp-hfbi fusion system	Conceived and designed the experiments	-	YES
5791008	29434617	NN	2	designed the experiments|performed the experiments for optimization and cryopreservation	designed the experiments	Conceived and designed the experiments	Methodology	YES
5791008	29434617	NN	2	designed the experiments|performed the experiments for optimization and cryopreservation	performed the experiments for optimization and cryopreservation	Performed the experiments	Investigation	YES
5791008	29434617	STH	2	designed the experiments|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5791008	29434617	STH	2	designed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6270656	25251191	Ang Zhang	PLoS52	polished the language	polished the language	Wrote the paper	Writing - Review & Editing	YES
6270656	25251191	Hua Li	PLoS52	polished the language	polished the language	Wrote the paper	Writing - Review & Editing	YES
6270656	25251191	Kai Wang	PLoS52	performed research and analyzed the data	performed research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270656	25251191	Yu Lin Fang	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270656	25251191	Zemei Guo	PLoS52	designed research|performed research and analyzed the data	designed research	Conceived and designed the experiments	Methodology	YES
6270656	25251191	Zemei Guo	PLoS52	designed research|performed research and analyzed the data	performed research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270656	25251191	Zhuo Min	PLoS52	designed research|performed research and analyzed the data|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
6270656	25251191	Zhuo Min	PLoS52	designed research|performed research and analyzed the data|wrote the paper	performed research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270656	25251191	Zhuo Min	PLoS52	designed research|performed research and analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5753036	29212815	All authors	2	were involved in discussing and interpreting the data	were involved in discussing and interpreting the data	Analyzed the data	Formal analysis	YES
5753036	29212815	DRA	2	supervised the project and wrote the manuscript	supervised the project and wrote the manuscript	Wrote the paper	Supervision|Writing - Original Draft	YES
5753036	29212815	MW	2	undertook most of the cloning studies	undertook most of the cloning studies	Performed the experiments	Investigation	YES
5753036	29212815	SRP	2	supervised the project and wrote the manuscript	supervised the project and wrote the manuscript	Wrote the paper	Supervision|Writing - Original Draft	YES
5753036	29212815	TNM	2	designed, organized, and oversaw the effort required for development the rabbit phospho rab8 and rab10 antibodies	designed, organized, and oversaw the effort required for development the rabbit phospho rab8 and rab10 antibodies	Conceived and designed the experiments|Performed the experiments	Investigation|Supervision	YES
5484656	28655217	All	2	animal experiment procedures were conducted in accordance with the guidelines of the animal welfare act and all procedures and protocols were approved by the institutional animal care and use committee of the sichuan agricultural university	animal experiment procedures were conducted in accordance with the guidelines of the animal welfare act and all procedures and protocols were approved by the institutional animal care and use committee of the sichuan agricultural university	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5484656	28655217	All authors	2	contributed to the design of the experiments|read and approved the final manuscript	contributed to the design of the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5484656	28655217	All authors	2	contributed to the design of the experiments|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5484656	28655217	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5484656	28655217	XQ	2	performed the experiments and drafted the manuscript	performed the experiments and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4416730	25933430	JW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416730	25933430	JW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416730	25933430	JW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416730	25933430	JW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416730	25933430	JW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416730	25933430	LZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416730	25933430	LZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416730	25933430	LZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416730	25933430	LZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416730	25933430	LZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416730	25933430	RH	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416730	25933430	RH	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5727985	29233090	AS-Z	2	designed the project|performed the computational analysis|wrote the manuscript	designed the project	Conceived and designed the experiments	Methodology	YES
5727985	29233090	AS-Z	2	designed the project|performed the computational analysis|wrote the manuscript	performed the computational analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5727985	29233090	AS-Z	2	designed the project|performed the computational analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5727985	29233090	DG	2	provided biological insights and checked the results|contributed to the statistical analysis|wrote the manuscript	provided biological insights and checked the results	-	-	NO
5727985	29233090	DG	2	provided biological insights and checked the results|contributed to the statistical analysis|wrote the manuscript	contributed to the statistical analysis	Analyzed the data	Formal analysis	YES
5727985	29233090	DG	2	provided biological insights and checked the results|contributed to the statistical analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5727985	29233090	HB	2	supervised the project	supervised the project	-	Supervision	YES
5727985	29233090	HC	2	checked the plots	checked the plots	-	-	NO
5727985	29233090	HP	2	contributed to the statistical analysis	contributed to the statistical analysis	Analyzed the data	Formal analysis	YES
5727985	29233090	HRS	2	provided biological insights and checked the results	provided biological insights and checked the results	-	-	NO
5727985	29233090	KA	2	provided biological insights and checked the results	provided biological insights and checked the results	-	-	NO
5727985	29233090	MJA-B	2	designed the project|wrote the manuscript	designed the project	Conceived and designed the experiments	Methodology	YES
5727985	29233090	MJA-B	2	designed the project|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5727985	29233090	MS	2	designed the project|supervised the project	designed the project	Conceived and designed the experiments	Methodology	YES
5727985	29233090	MS	2	designed the project|supervised the project	supervised the project	-	Supervision	YES
5727985	29233090	MT	2	provided biological insights and checked the results	provided biological insights and checked the results	-	-	NO
5727985	29233090	RJT	2	provided biological insights and checked the results	provided biological insights and checked the results	-	-	NO
5791383	29434612	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5791383	29434612	CY	PLoS52	revised the intellectual content of this manuscript	revised the intellectual content of this manuscript	Wrote the paper	Writing - Review & Editing	YES
5791383	29434612	DG	PLoS52	designed the research|contributed new models	designed the research	Conceived and designed the experiments	Methodology	YES
5791383	29434612	DG	PLoS52	designed the research|contributed new models	contributed new models	Performed the experiments	Methodology	YES
5791383	29434612	DL	PLoS52	contributed new models	contributed new models	Performed the experiments	Methodology	YES
5791383	29434612	LL	PLoS52	designed the research|contributed new models|revised the intellectual content of this manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
5791383	29434612	LL	PLoS52	designed the research|contributed new models|revised the intellectual content of this manuscript	contributed new models	Performed the experiments	Methodology	YES
5791383	29434612	LL	PLoS52	designed the research|contributed new models|revised the intellectual content of this manuscript	revised the intellectual content of this manuscript	Wrote the paper	Writing - Review & Editing	YES
5791383	29434612	MC	PLoS52	designed the research|performed the experiments|analyzed the data|wrote the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
5791383	29434612	MC	PLoS52	designed the research|performed the experiments|analyzed the data|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5791383	29434612	MC	PLoS52	designed the research|performed the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5791383	29434612	MC	PLoS52	designed the research|performed the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5791383	29434612	SJ	PLoS52	analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5791383	29434612	SJ	PLoS52	analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5791383	29434612	XC	PLoS52	contributed new models	contributed new models	Performed the experiments	Methodology	YES
5791383	29434612	XF	PLoS52	contributed new models	contributed new models	Performed the experiments	Methodology	YES
5791383	29434612	XL	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5791383	29434612	XL	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
1952072	17786204	AF	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1952072	17786204	AF	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1952072	17786204	CT	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1952072	17786204	FM	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1952072	17786204	FM	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1952072	17786204	HH	PLoS5	Designed the experiments/the study|Contributed to the writing of the paper	Designed the experiments/the study	Conceived and designed the experiments	Methodology	YES
1952072	17786204	HH	PLoS5	Designed the experiments/the study|Contributed to the writing of the paper	Contributed to the writing of the paper	Wrote the paper	Writing - Original Draft	YES
1952072	17786204	HS	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1952072	17786204	HS	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1952072	17786204	KK	PLoS5	Performed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1952072	17786204	KK	PLoS5	Performed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1952072	17786204	NS	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1952072	17786204	NS	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1952072	17786204	OT	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1952072	17786204	SS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4628962	26558267	Bryant Anthony Irawan	2	contributed to conception and design of the work|contributed to acquisition of data or analysis and interpretation of data|contributed to final approval of the version to be published	contributed to conception and design of the work	Conceived and designed the experiments	Conceptualization	YES
4628962	26558267	Bryant Anthony Irawan	2	contributed to conception and design of the work|contributed to acquisition of data or analysis and interpretation of data|contributed to final approval of the version to be published	contributed to acquisition of data or analysis and interpretation of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
4628962	26558267	Bryant Anthony Irawan	2	contributed to conception and design of the work|contributed to acquisition of data or analysis and interpretation of data|contributed to final approval of the version to be published	contributed to final approval of the version to be published	-	-	NO
4628962	26558267	Mohammad Khursheed Alam	2	contributed to conception and design of the work|contributed to final approval of the version to be published	contributed to conception and design of the work	Conceived and designed the experiments	Conceptualization	YES
4628962	26558267	Mohammad Khursheed Alam	2	contributed to conception and design of the work|contributed to final approval of the version to be published	contributed to final approval of the version to be published	-	-	NO
4628962	26558267	Ninin Sukminingrum	2	contributed to conception and design of the work|contributed to final approval of the version to be published	contributed to conception and design of the work	Conceived and designed the experiments	Conceptualization	YES
4628962	26558267	Ninin Sukminingrum	2	contributed to conception and design of the work|contributed to final approval of the version to be published	contributed to final approval of the version to be published	-	-	NO
4628962	26558267	Saman Malik Masudi	2	contributed to conception and design of the work|contributed to acquisition of data or analysis and interpretation of data|contributed to final approval of the version to be published	contributed to conception and design of the work	Conceived and designed the experiments	Conceptualization	YES
4628962	26558267	Saman Malik Masudi	2	contributed to conception and design of the work|contributed to acquisition of data or analysis and interpretation of data|contributed to final approval of the version to be published	contributed to acquisition of data or analysis and interpretation of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
4628962	26558267	Saman Malik Masudi	2	contributed to conception and design of the work|contributed to acquisition of data or analysis and interpretation of data|contributed to final approval of the version to be published	contributed to final approval of the version to be published	-	-	NO
4628962	26558267	Stacey Natalie Irawan	2	contributed to conception and design of the work|contributed to acquisition of data or analysis and interpretation of data|contributed to final approval of the version to be published	contributed to conception and design of the work	Conceived and designed the experiments	Conceptualization	YES
4628962	26558267	Stacey Natalie Irawan	2	contributed to conception and design of the work|contributed to acquisition of data or analysis and interpretation of data|contributed to final approval of the version to be published	contributed to acquisition of data or analysis and interpretation of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
4628962	26558267	Stacey Natalie Irawan	2	contributed to conception and design of the work|contributed to acquisition of data or analysis and interpretation of data|contributed to final approval of the version to be published	contributed to final approval of the version to be published	-	-	NO
6270657	25325153	ChanKyu Kang	2	designed and performed the experiments	designed and performed the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6270657	25325153	Changhyun Roh	2	designed and performed the experiments	designed and performed the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6137941	30217203	AC	2	assisted with the data interpretation	assisted with the data interpretation	Analyzed the data	Formal analysis	YES
6137941	30217203	AF	2	assisted with the data interpretation	assisted with the data interpretation	Analyzed the data	Formal analysis	YES
6137941	30217203	All authors	2	assisted with manuscript revision and approved the final manuscript	assisted with manuscript revision and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6137941	30217203	RB	2	assisted with the data interpretation	assisted with the data interpretation	Analyzed the data	Formal analysis	YES
6137941	30217203	SJ	2	collected and analysed the data	collected and analysed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6137941	30217203	TK	2	assisted with the data interpretation	assisted with the data interpretation	Analyzed the data	Formal analysis	YES
4416731	25933382	CJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416731	25933382	CJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4416731	25933382	CJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416731	25933382	KLD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416731	25933382	KLD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416731	25933382	KLD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416731	25933382	KLD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416731	25933382	SB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416731	25933382	SB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4416731	25933382	SB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416731	25933382	TCB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416731	25933382	TCB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416731	25933382	TCB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416731	25933382	TCB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5770787	29158324	AJ-O	2	performed some of the imaging and most of the biochemical and tissue culture work	performed some of the imaging and most of the biochemical and tissue culture work	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
5770787	29158324	AK	2	performed some of the imaging and most of the biochemical and tissue culture work	performed some of the imaging and most of the biochemical and tissue culture work	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
5770787	29158324	FS	2	planned the experiments, performed most of the imaging work, and wrote the manuscript	planned the experiments, performed most of the imaging work, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Investigation|Visualization|Writing - Original Draft	YES
5770787	29158324	GTPases	2	helped with experimental design	helped with experimental design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5770787	29158324	HN	2	performed most of the molecular biology work	performed most of the molecular biology work	Performed the experiments	Investigation	YES
5770787	29158324	RAB	2	helped with experimental design	helped with experimental design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5729250	29237414	CMS	2	conceived and oversaw the study|designed the analytical strategy|interpreted data	conceived and oversaw the study	Conceived and designed the experiments	Conceptualization|Supervision	YES
5729250	29237414	CMS	2	conceived and oversaw the study|designed the analytical strategy|interpreted data	designed the analytical strategy	Conceived and designed the experiments	-	YES
5729250	29237414	CMS	2	conceived and oversaw the study|designed the analytical strategy|interpreted data	interpreted data	Analyzed the data	Formal analysis	YES
5729250	29237414	CS	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5729250	29237414	EG	2	designed the analytical strategy|analysed data|interpreted data|drafted the manuscript	designed the analytical strategy	Conceived and designed the experiments	-	YES
5729250	29237414	EG	2	designed the analytical strategy|analysed data|interpreted data|drafted the manuscript	analysed data	Analyzed the data	Formal analysis	YES
5729250	29237414	EG	2	designed the analytical strategy|analysed data|interpreted data|drafted the manuscript	interpreted data	Analyzed the data	Formal analysis	YES
5729250	29237414	EG	2	designed the analytical strategy|analysed data|interpreted data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5729250	29237414	HC	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5729250	29237414	HM	2	performed experiments|analysed data|interpreted data|drafted the manuscript	performed experiments	Performed the experiments	Investigation	YES
5729250	29237414	HM	2	performed experiments|analysed data|interpreted data|drafted the manuscript	analysed data	Analyzed the data	Formal analysis	YES
5729250	29237414	HM	2	performed experiments|analysed data|interpreted data|drafted the manuscript	interpreted data	Analyzed the data	Formal analysis	YES
5729250	29237414	HM	2	performed experiments|analysed data|interpreted data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5729250	29237414	JEC	2	conceived and oversaw the study|designed the analytical strategy|performed experiments|interpreted data|drafted the manuscript	conceived and oversaw the study	Conceived and designed the experiments	Conceptualization|Supervision	YES
5729250	29237414	JEC	2	conceived and oversaw the study|designed the analytical strategy|performed experiments|interpreted data|drafted the manuscript	designed the analytical strategy	Conceived and designed the experiments	-	YES
5729250	29237414	JEC	2	conceived and oversaw the study|designed the analytical strategy|performed experiments|interpreted data|drafted the manuscript	performed experiments	Performed the experiments	Investigation	YES
5729250	29237414	JEC	2	conceived and oversaw the study|designed the analytical strategy|performed experiments|interpreted data|drafted the manuscript	interpreted data	Analyzed the data	Formal analysis	YES
5729250	29237414	JEC	2	conceived and oversaw the study|designed the analytical strategy|performed experiments|interpreted data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5729250	29237414	KB	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5729250	29237414	PEY	2	analysed data	analysed data	Analyzed the data	Formal analysis	YES
5729250	29237414	SH	2	interpreted data|drafted the manuscript	interpreted data	Analyzed the data	Formal analysis	YES
5729250	29237414	SH	2	interpreted data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5797444	29434609	H-YM	PLoS52	who prepared the materials and total rna extraction	who prepared the materials and total rna extraction	Performed the experiments	Investigation	YES
5797444	29434609	KB	PLoS52	contributed to design this project and revised this manuscript	contributed to design this project and revised this manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5797444	29434609	PL	PLoS52	designed the experiments|contributed to data analysis and interpretation	designed the experiments	Conceived and designed the experiments	Methodology	YES
5797444	29434609	PL	PLoS52	designed the experiments|contributed to data analysis and interpretation	contributed to data analysis and interpretation	Analyzed the data	Formal analysis	YES
5797444	29434609	S-QO	PLoS52	designed the experiments|wrote the paper	designed the experiments	Conceived and designed the experiments	Methodology	YES
5797444	29434609	S-QO	PLoS52	designed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5797444	29434609	W-YF	PLoS52	who prepared the materials and total rna extraction	who prepared the materials and total rna extraction	Performed the experiments	Investigation	YES
5797444	29434609	X-XC	PLoS52	who prepared the materials and total rna extraction	who prepared the materials and total rna extraction	Performed the experiments	Investigation	YES
5797444	29434609	YG	PLoS52	who prepared the materials and total rna extraction	who prepared the materials and total rna extraction	Performed the experiments	Investigation	YES
5797444	29434609	YZ	PLoS52	who prepared the materials and total rna extraction	who prepared the materials and total rna extraction	Performed the experiments	Investigation	YES
5484659	28655216	CG	1	Design of the experiments|Data analyses	Design of the experiments	Conceived and designed the experiments	Methodology	YES
5484659	28655216	CG	1	Design of the experiments|Data analyses	Data analyses	Analyzed the data	Formal analysis	YES
5484659	28655216	CYY	1	Experiments performed by	Experiments performed by	Performed the experiments	Investigation	YES
5484659	28655216	DF	1	Design of the experiments|Data analyses	Design of the experiments	Conceived and designed the experiments	Methodology	YES
5484659	28655216	DF	1	Design of the experiments|Data analyses	Data analyses	Analyzed the data	Formal analysis	YES
5484659	28655216	GYA	1	Experiments performed by	Experiments performed by	Performed the experiments	Investigation	YES
5484659	28655216	JWC	1	Design of the experiments|Experiments performed by|Data analyses|The article written by	Design of the experiments	Conceived and designed the experiments	Methodology	YES
5484659	28655216	JWC	1	Design of the experiments|Experiments performed by|Data analyses|The article written by	Experiments performed by	Performed the experiments	Investigation	YES
5484659	28655216	JWC	1	Design of the experiments|Experiments performed by|Data analyses|The article written by	Data analyses	Analyzed the data	Formal analysis	YES
5484659	28655216	JWC	1	Design of the experiments|Experiments performed by|Data analyses|The article written by	The article written by	Wrote the paper	Writing - Original Draft	YES
5484659	28655216	KGC	1	Design of the experiments|Data analyses|The article written by	Design of the experiments	Conceived and designed the experiments	Methodology	YES
5484659	28655216	KGC	1	Design of the experiments|Data analyses|The article written by	Data analyses	Analyzed the data	Formal analysis	YES
5484659	28655216	KGC	1	Design of the experiments|Data analyses|The article written by	The article written by	Wrote the paper	Writing - Original Draft	YES
5484659	28655216	TMC	1	Design of the experiments|Experiments performed by|Data analyses|The article written by	Design of the experiments	Conceived and designed the experiments	Methodology	YES
5484659	28655216	TMC	1	Design of the experiments|Experiments performed by|Data analyses|The article written by	Experiments performed by	Performed the experiments	Investigation	YES
5484659	28655216	TMC	1	Design of the experiments|Experiments performed by|Data analyses|The article written by	Data analyses	Analyzed the data	Formal analysis	YES
5484659	28655216	TMC	1	Design of the experiments|Experiments performed by|Data analyses|The article written by	The article written by	Wrote the paper	Writing - Original Draft	YES
5484659	28655216	WFY	1	Data analyses	Data analyses	Analyzed the data	Formal analysis	YES
5484659	28655216	WSST	1	Design of the experiments|The article written by	Design of the experiments	Conceived and designed the experiments	Methodology	YES
5484659	28655216	WSST	1	Design of the experiments|The article written by	The article written by	Wrote the paper	Writing - Original Draft	YES
5484659	28655216	YD	1	Design of the experiments|Data analyses|The article written by	Design of the experiments	Conceived and designed the experiments	Methodology	YES
5484659	28655216	YD	1	Design of the experiments|Data analyses|The article written by	Data analyses	Analyzed the data	Formal analysis	YES
5484659	28655216	YD	1	Design of the experiments|Data analyses|The article written by	The article written by	Wrote the paper	Writing - Original Draft	YES
5484659	28655216	YLL	1	Experiments performed by	Experiments performed by	Performed the experiments	Investigation	YES
1952073	17786215	AD	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1952073	17786215	AD	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1952073	17786215	DF	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1952073	17786215	DQ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1952073	17786215	MC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1952073	17786215	MC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1952073	17786215	MC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1952073	17786215	MC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1952073	17786215	NG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1952073	17786215	RP	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1952073	17786215	SD	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1952073	17786215	SD	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1952073	17786215	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1952073	17786215	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1952073	17786215	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1952073	17786215	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1952073	17786215	SS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416734	25933287	AAF	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416734	25933287	ACCS	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416734	25933287	AFA	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416734	25933287	AM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4416734	25933287	AM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416734	25933287	CBM	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4416734	25933287	CBM	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416734	25933287	CGFL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Supervised research	Performed the experiments	Performed the experiments	Investigation	YES
4416734	25933287	CGFL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Supervised research	Analyzed the data	Analyzed the data	Formal analysis	YES
4416734	25933287	CGFL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Supervised research	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416734	25933287	CGFL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Supervised research	Supervised research	-	Supervision	YES
4416734	25933287	DDR	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Supervised research	Performed the experiments	Performed the experiments	Investigation	YES
4416734	25933287	DDR	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Supervised research	Analyzed the data	Analyzed the data	Formal analysis	YES
4416734	25933287	DDR	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Supervised research	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416734	25933287	DDR	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Supervised research	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416734	25933287	DDR	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Supervised research	Supervised research	-	Supervision	YES
4416734	25933287	DZ	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416734	25933287	DZ	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416734	25933287	FPMS	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416734	25933287	GADR	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4416734	25933287	GADR	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416734	25933287	ILRF	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416734	25933287	JDBR	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416734	25933287	JDBR	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416734	25933287	MM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416734	25933287	MPN	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
6270658	25230124	All authors	PLoS52	discussed the results and commented on the manuscript	discussed the results and commented on the manuscript	-	-	NO
6270658	25230124	B.V.O.S.	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
6270658	25230124	B.V.O.S.	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
6270658	25230124	F.N.	PLoS52	designed the research study|analyzed the data|wrote the paper	designed the research study	Conceived and designed the experiments	Methodology	YES
6270658	25230124	F.N.	PLoS52	designed the research study|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
6270658	25230124	F.N.	PLoS52	designed the research study|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270658	25230124	G.E.C.M.	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
6270658	25230124	J.C.F.S.	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
6270658	25230124	J.M.B.-F.	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
6270658	25230124	J.M.B.-F.	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
6270658	25230124	J.X.A.-J.	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
6270658	25230124	L.H.A.C.-S.	PLoS52	designed the research study|analyzed the data|wrote the paper	designed the research study	Conceived and designed the experiments	Methodology	YES
6270658	25230124	L.H.A.C.-S.	PLoS52	designed the research study|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
6270658	25230124	L.H.A.C.-S.	PLoS52	designed the research study|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270658	25230124	M.S.A.-M.	PLoS52	designed the research study|analyzed the data|wrote the paper	designed the research study	Conceived and designed the experiments	Methodology	YES
6270658	25230124	M.S.A.-M.	PLoS52	designed the research study|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
6270658	25230124	M.S.A.-M.	PLoS52	designed the research study|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270658	25230124	T.M.S.S.	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
4628971	26558271	C. O. B. Teixeira	2	contributed equally to this work	contributed equally to this work	-	-	NO
5729405	29237423	CRG	2	designed the experiments and interpreted all results|contributed to animal sampling	designed the experiments and interpreted all results	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5729405	29237423	CRG	2	designed the experiments and interpreted all results|contributed to animal sampling	contributed to animal sampling	Performed the experiments	Investigation	YES
5729405	29237423	DE	2	performed rna seq on the getplage platform	performed rna seq on the getplage platform	Performed the experiments	Investigation	YES
5729405	29237423	E. All	2	authors improved the manuscript	authors improved the manuscript	Wrote the paper	Writing - Review & Editing	YES
5729405	29237423	GL	2	contributed to animal sampling|organized all procedures for animal sampling and safe sample storage	contributed to animal sampling	Performed the experiments	Investigation	YES
5729405	29237423	GL	2	contributed to animal sampling|organized all procedures for animal sampling and safe sample storage	organized all procedures for animal sampling and safe sample storage	Performed the experiments	Investigation	YES
5729405	29237423	JE	2	designed the experiments and interpreted all results|for computational analyses|contributed to animal sampling	designed the experiments and interpreted all results	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5729405	29237423	JE	2	designed the experiments and interpreted all results|for computational analyses|contributed to animal sampling	for computational analyses	Analyzed the data	Formal analysis	YES
5729405	29237423	JE	2	designed the experiments and interpreted all results|for computational analyses|contributed to animal sampling	contributed to animal sampling	Performed the experiments	Investigation	YES
5729405	29237423	TM	2	designed the experiments and interpreted all results	designed the experiments and interpreted all results	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5729405	29237423	YRC	2	contributed to network analyses	contributed to network analyses	Analyzed the data	Formal analysis	YES
6139124	30219082	CO	2	contributed to the conduct of the research, data collection, and analysis	contributed to the conduct of the research, data collection, and analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
6139124	30219082	DDPB	2	wrote the draft of the manuscript	wrote the draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
6139124	30219082	HG	2	contributed to the conduct of the research, data collection, and analysis	contributed to the conduct of the research, data collection, and analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
6139124	30219082	JRK	2	planned and designed the research, wrote the manuscript, and are responsible for the final content	planned and designed the research, wrote the manuscript, and are responsible for the final content	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
6139124	30219082	KS	2	planned and designed the research, wrote the manuscript, and are responsible for the final content	planned and designed the research, wrote the manuscript, and are responsible for the final content	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
6139124	30219082	MT	2	contributed to the conduct of the research, data collection, and analysis|contributed to the conduct of the research, data collection, and analysis	contributed to the conduct of the research, data collection, and analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
6139124	30219082	MT	2	contributed to the conduct of the research, data collection, and analysis|contributed to the conduct of the research, data collection, and analysis	contributed to the conduct of the research, data collection, and analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
6139124	30219082	NS	2	contributed to the conduct of the research, data collection, and analysis	contributed to the conduct of the research, data collection, and analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
6139124	30219082	RP	2	contributed to the conduct of the research, data collection, and analysis	contributed to the conduct of the research, data collection, and analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
6139124	30219082	VC	2	contributed to the conduct of the research, data collection, and analysis	contributed to the conduct of the research, data collection, and analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5771398	29212814	AN	4	EM data collection was carried out by	EM data collection was carried out by	Performed the experiments	Investigation	YES
5771398	29212814	MRS	4	The study was designed by|Image processing was carried out by|The manuscript was written by	The study was designed by	Conceived and designed the experiments	Methodology	YES
5771398	29212814	MRS	4	The study was designed by|Image processing was carried out by|The manuscript was written by	Image processing was carried out by	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
5771398	29212814	MRS	4	The study was designed by|Image processing was carried out by|The manuscript was written by	The manuscript was written by	Wrote the paper	Writing - Original Draft	YES
5771398	29212814	VL	4	The study was designed by|EM data collection was carried out by|Image processing was carried out by|All other procedures were carried out by|The manuscript was written by	The study was designed by	Conceived and designed the experiments	Methodology	YES
5771398	29212814	VL	4	The study was designed by|EM data collection was carried out by|Image processing was carried out by|All other procedures were carried out by|The manuscript was written by	EM data collection was carried out by	Performed the experiments	Investigation	YES
5771398	29212814	VL	4	The study was designed by|EM data collection was carried out by|Image processing was carried out by|All other procedures were carried out by|The manuscript was written by	Image processing was carried out by	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
5771398	29212814	VL	4	The study was designed by|EM data collection was carried out by|Image processing was carried out by|All other procedures were carried out by|The manuscript was written by	All other procedures were carried out by	Performed the experiments	Investigation	YES
5771398	29212814	VL	4	The study was designed by|EM data collection was carried out by|Image processing was carried out by|All other procedures were carried out by|The manuscript was written by	The manuscript was written by	Wrote the paper	Writing - Original Draft	YES
4628972	26558272	Rongfei Jia	2	contributed equally to this work	contributed equally to this work	-	-	NO
4628972	26558272	Shulan Ma	2	contributed equally to this work	contributed equally to this work	-	-	NO
4416735	25933067	BB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416735	25933067	BB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416735	25933067	BB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416735	25933067	BB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416735	25933067	CSS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416735	25933067	CSS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4416735	25933067	CSS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416735	25933067	DC	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416735	25933067	EMR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416735	25933067	EMR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416735	25933067	EMR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416735	25933067	EMR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416735	25933067	GMC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416735	25933067	GMC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416735	25933067	GMC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416735	25933067	KD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416735	25933067	KD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416735	25933067	KD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416735	25933067	MF	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416735	25933067	WL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416735	25933067	WL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4416735	25933067	WL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5797473	29434615	CB	2	performed library preparation, rt qpcrs, rna seq, and smallrna analyses and statistical analyses|reviewed by all other authors	performed library preparation, rt qpcrs, rna seq, and smallrna analyses and statistical analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5797473	29434615	CB	2	performed library preparation, rt qpcrs, rna seq, and smallrna analyses and statistical analyses|reviewed by all other authors	reviewed by all other authors	-	-	NO
5797473	29434615	GV	2	conceived the experiments	conceived the experiments	Conceived and designed the experiments	Conceptualization	YES
5797473	29434615	LC	2	conceived the experiments	conceived the experiments	Conceived and designed the experiments	Conceptualization	YES
5797473	29434615	MB	2	performed plant infection, sampling, phenotyping and rna extractions	performed plant infection, sampling, phenotyping and rna extractions	Performed the experiments	Investigation	YES
5797473	29434615	MM	2	contributed to rna seq data analysis	contributed to rna seq data analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5797473	29434615	PB	2	performed bioinformatic analysis of the rna seq experiment	performed bioinformatic analysis of the rna seq experiment	Performed the experiments	Formal analysis|Investigation	YES
5797473	29434615	PF	2	contributed to the bioinformatic analysis of the smallrna seq experiment	contributed to the bioinformatic analysis of the smallrna seq experiment	Performed the experiments	Formal analysis|Investigation	YES
5797473	29434615	TO	2	conceived the experiments	conceived the experiments	Conceived and designed the experiments	Conceptualization	YES
5797473	29434615	XH	2	conducted rt qpcrs for mrnas	conducted rt qpcrs for mrnas	Performed the experiments	Investigation	YES
5797473	29434615	ZY	2	contributed to the writing	contributed to the writing	Wrote the paper	-	YES
5487312	28658944	All authors	2	designed the study, performed the experiments, and analyzed the data|read and approved the final manuscript	designed the study, performed the experiments, and analyzed the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5487312	28658944	All authors	2	designed the study, performed the experiments, and analyzed the data|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5487312	28658944	HH	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5487312	28658944	TA	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5487312	28658944	TH	2	wrote the manuscript|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5487312	28658944	TH	2	wrote the manuscript|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
1952074	17786201	CB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1952074	17786201	CB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1952074	17786201	CM	PLoS5	Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1952074	17786201	CM	PLoS5	Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1952074	17786201	CM	PLoS5	Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1952074	17786201	DS	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1952074	17786201	DS	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1952074	17786201	EK	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1952074	17786201	ET	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1952074	17786201	ET	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1952074	17786201	ET	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1952074	17786201	JD	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1952074	17786201	LD	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1952074	17786201	LO	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1952074	17786201	MG	PLoS5	Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1952074	17786201	MG	PLoS5	Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1952074	17786201	MM	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1952074	17786201	MM	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1952074	17786201	MR	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1952074	17786201	MR	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1952074	17786201	MV	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1952074	17786201	OR	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1952074	17786201	RM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1952074	17786201	RM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1952074	17786201	RM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1952074	17786201	RM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1952074	17786201	RV	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1952074	17786201	RV	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1952074	17786201	SF	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1952074	17786201	SZ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1952074	17786201	TK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1952074	17786201	TK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1952074	17786201	TK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1952074	17786201	TK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1952074	17786201	VS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
6150988	30241477	BSR	2	assisted in study design, data interpretation and manuscript preparation	assisted in study design, data interpretation and manuscript preparation	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
6150988	30241477	DJV	2	were responsible for the study design, coordination of the study, oversight of data collection and manuscript preparation	were responsible for the study design, coordination of the study, oversight of data collection and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Project administration|Supervision|Writing - Original Draft	YES
6150988	30241477	GPY	2	were responsible for the study design, coordination of the study, oversight of data collection and manuscript preparation	were responsible for the study design, coordination of the study, oversight of data collection and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Project administration|Supervision|Writing - Original Draft	YES
6150988	30241477	HJB	2	assisted in study design, data interpretation and manuscript preparation	assisted in study design, data interpretation and manuscript preparation	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
6150988	30241477	ILB	2	assisted in study design, data interpretation and manuscript preparation	assisted in study design, data interpretation and manuscript preparation	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
6150988	30241477	RW	2	was responsible for the statistical analysis and manuscript preparation	was responsible for the statistical analysis and manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6150988	30241477	SO	2	were responsible for the study design, coordination of the study, oversight of data collection and manuscript preparation	were responsible for the study design, coordination of the study, oversight of data collection and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Project administration|Supervision|Writing - Original Draft	YES
4416736	25933033	MR	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4416736	25933033	MR	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416736	25933033	PN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416736	25933033	PN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416736	25933033	PN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416736	25933033	PN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416736	25933033	PN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416736	25933033	QL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416736	25933033	XC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416736	25933033	XC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416736	25933033	XC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416736	25933033	XC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416736	25933033	XC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1952107	17786195	BW	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1952107	17786195	CB	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1952107	17786195	CB	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1952107	17786195	DH	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1952107	17786195	DH	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1952107	17786195	DN	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1952107	17786195	DN	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1952107	17786195	GL	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1952107	17786195	GL	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1952107	17786195	JM	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1952107	17786195	JM	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1952107	17786195	MR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1952107	17786195	MR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1952107	17786195	MR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1952107	17786195	MR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1952107	17786195	NF	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1952107	17786195	NF	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1952107	17786195	NJ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1952107	17786195	VJ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1952107	17786195	WD	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1952107	17786195	WD	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5793797	29237698	JE	PLoS52	performed the experiments|conceived the experiments and analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5793797	29237698	JE	PLoS52	performed the experiments|conceived the experiments and analyzed the data	conceived the experiments and analyzed the data	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
5793797	29237698	JG	PLoS52	performed the experiments|conceived the experiments and analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5793797	29237698	JG	PLoS52	performed the experiments|conceived the experiments and analyzed the data	conceived the experiments and analyzed the data	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
5793797	29237698	ME-W	PLoS52	performed the experiments|conceived the experiments and analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5793797	29237698	ME-W	PLoS52	performed the experiments|conceived the experiments and analyzed the data	conceived the experiments and analyzed the data	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
5793797	29237698	MH	PLoS52	performed the experiments|conceived the experiments and analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5793797	29237698	MH	PLoS52	performed the experiments|conceived the experiments and analyzed the data	conceived the experiments and analyzed the data	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
5793797	29237698	PRW	PLoS52	performed the experiments|conceived the experiments and analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5793797	29237698	PRW	PLoS52	performed the experiments|conceived the experiments and analyzed the data	conceived the experiments and analyzed the data	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
5793797	29237698	SA	PLoS52	conceived the experiments and analyzed the data|wrote the manuscript|managed the project	conceived the experiments and analyzed the data	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
5793797	29237698	SA	PLoS52	conceived the experiments and analyzed the data|wrote the manuscript|managed the project	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5793797	29237698	SA	PLoS52	conceived the experiments and analyzed the data|wrote the manuscript|managed the project	managed the project	-	Project administration	YES
5793797	29237698	SB	PLoS52	performed the experiments|conceived the experiments and analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5793797	29237698	SB	PLoS52	performed the experiments|conceived the experiments and analyzed the data	conceived the experiments and analyzed the data	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
5793797	29237698	SG	PLoS52	performed the experiments|conceived the experiments and analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5793797	29237698	SG	PLoS52	performed the experiments|conceived the experiments and analyzed the data	conceived the experiments and analyzed the data	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
5793797	29237698	WRH	PLoS52	conceived the experiments and analyzed the data|managed the project	conceived the experiments and analyzed the data	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
5793797	29237698	WRH	PLoS52	conceived the experiments and analyzed the data|managed the project	managed the project	-	Project administration	YES
6270660	24619301	A.F.	PLoS52	performed research and analyzed the data	performed research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270660	24619301	A.R.	PLoS52	performed research and analyzed the data	performed research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270660	24619301	A.Ro	PLoS52	performed research and analyzed the data	performed research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270660	24619301	C.C.	PLoS52	performed research and analyzed the data	performed research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270660	24619301	C.F.	PLoS52	performed research and analyzed the data	performed research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270660	24619301	C.H.	PLoS52	designed research|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
6270660	24619301	C.H.	PLoS52	designed research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270660	24619301	E.G.	PLoS52	performed research and analyzed the data	performed research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270660	24619301	E.L.	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270660	24619301	F.L.	PLoS52	performed research and analyzed the data	performed research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270660	24619301	F.M.	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270660	24619301	J.D.	PLoS52	designed research	designed research	Conceived and designed the experiments	Methodology	YES
6270660	24619301	O.F.	PLoS52	designed research|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
6270660	24619301	O.F.	PLoS52	designed research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270660	24619301	S.R.	PLoS52	performed research and analyzed the data	performed research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270660	24619301	V.B.	PLoS52	performed research and analyzed the data	performed research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6161339	30261929	CG	2	collected samples, carried out analysis, wrote the paper, reviewed and accepted its final version	collected samples, carried out analysis, wrote the paper, reviewed and accepted its final version	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6161339	30261929	FB	2	collected samples, carried out analysis, wrote the paper, reviewed and accepted its final version	collected samples, carried out analysis, wrote the paper, reviewed and accepted its final version	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6161339	30261929	FD	2	collected samples, carried out analysis, wrote the paper, reviewed and accepted its final version	collected samples, carried out analysis, wrote the paper, reviewed and accepted its final version	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6161339	30261929	FK	2	collected samples, carried out analysis, wrote the paper, reviewed and accepted its final version	collected samples, carried out analysis, wrote the paper, reviewed and accepted its final version	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6161339	30261929	ID	2	collected samples, carried out analysis, wrote the paper, reviewed and accepted its final version	collected samples, carried out analysis, wrote the paper, reviewed and accepted its final version	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6161339	30261929	KS	2	collected samples, carried out analysis, wrote the paper, reviewed and accepted its final version	collected samples, carried out analysis, wrote the paper, reviewed and accepted its final version	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6161339	30261929	MA	2	collected samples, carried out analysis, wrote the paper, reviewed and accepted its final version	collected samples, carried out analysis, wrote the paper, reviewed and accepted its final version	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6161339	30261929	MAE	2	collected samples, carried out analysis, wrote the paper, reviewed and accepted its final version|is responsible for the integrity of the work as a whole	collected samples, carried out analysis, wrote the paper, reviewed and accepted its final version	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6161339	30261929	MAE	2	collected samples, carried out analysis, wrote the paper, reviewed and accepted its final version|is responsible for the integrity of the work as a whole	is responsible for the integrity of the work as a whole	-	-	NO
6161339	30261929	NY	2	collected samples, carried out analysis, wrote the paper, reviewed and accepted its final version	collected samples, carried out analysis, wrote the paper, reviewed and accepted its final version	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5487313	28658945	AD	PLoS52	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5487313	28658945	AS	PLoS52	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5487313	28658945	All	PLoS52	engaged for writing of the manuscript	engaged for writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5487313	28658945	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5487313	28658945	CG	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5487313	28658945	LS	PLoS52	advised for the overall study|is a senior professor	advised for the overall study	-	-	NO
5487313	28658945	LS	PLoS52	advised for the overall study|is a senior professor	is a senior professor	-	-	NO
5487313	28658945	MW	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5487313	28658945	NF	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5487313	28658945	UB	PLoS52	selected and recruited the patient for the study	selected and recruited the patient for the study	Performed the experiments	Investigation	YES
4416744	25933377	JDH	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416744	25933377	JDH	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416744	25933377	MKMU	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416744	25933377	MMR	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416744	25933377	MMR	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416744	25933377	MSRK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416744	25933377	MTR	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416744	25933377	MTR	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416744	25933377	RK	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416744	25933377	SB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416744	25933377	SB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416744	25933377	SB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416744	25933377	SB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416744	25933377	SIU	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416744	25933377	SIU	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416744	25933377	TA	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416744	25933377	TA	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5731093	29246115	AK	PLoS52	designed the research|performed the research|contributed new reagents/analytical tools|analysed data|wrote the paper	designed the research	Conceived and designed the experiments	Methodology	YES
5731093	29246115	AK	PLoS52	designed the research|performed the research|contributed new reagents/analytical tools|analysed data|wrote the paper	performed the research	Performed the experiments	Investigation	YES
5731093	29246115	AK	PLoS52	designed the research|performed the research|contributed new reagents/analytical tools|analysed data|wrote the paper	contributed new reagents/analytical tools	Contributed reagents/materials/analysis tools	Resources	YES
5731093	29246115	AK	PLoS52	designed the research|performed the research|contributed new reagents/analytical tools|analysed data|wrote the paper	analysed data	Analyzed the data	Formal analysis	YES
5731093	29246115	AK	PLoS52	designed the research|performed the research|contributed new reagents/analytical tools|analysed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5731093	29246115	GT	PLoS52	designed the research|performed the research|wrote the paper	designed the research	Conceived and designed the experiments	Methodology	YES
5731093	29246115	GT	PLoS52	designed the research|performed the research|wrote the paper	performed the research	Performed the experiments	Investigation	YES
5731093	29246115	GT	PLoS52	designed the research|performed the research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5731093	29246115	HT	PLoS52	designed the research|performed the research|wrote the paper	designed the research	Conceived and designed the experiments	Methodology	YES
5731093	29246115	HT	PLoS52	designed the research|performed the research|wrote the paper	performed the research	Performed the experiments	Investigation	YES
5731093	29246115	HT	PLoS52	designed the research|performed the research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5731093	29246115	MB	PLoS52	designed the research|performed the research|contributed new reagents/analytical tools|analysed data|wrote the paper	designed the research	Conceived and designed the experiments	Methodology	YES
5731093	29246115	MB	PLoS52	designed the research|performed the research|contributed new reagents/analytical tools|analysed data|wrote the paper	performed the research	Performed the experiments	Investigation	YES
5731093	29246115	MB	PLoS52	designed the research|performed the research|contributed new reagents/analytical tools|analysed data|wrote the paper	contributed new reagents/analytical tools	Contributed reagents/materials/analysis tools	Resources	YES
5731093	29246115	MB	PLoS52	designed the research|performed the research|contributed new reagents/analytical tools|analysed data|wrote the paper	analysed data	Analyzed the data	Formal analysis	YES
5731093	29246115	MB	PLoS52	designed the research|performed the research|contributed new reagents/analytical tools|analysed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5731093	29246115	NR	PLoS52	designed the research|performed the research|contributed new reagents/analytical tools|analysed data|wrote the paper	designed the research	Conceived and designed the experiments	Methodology	YES
5731093	29246115	NR	PLoS52	designed the research|performed the research|contributed new reagents/analytical tools|analysed data|wrote the paper	performed the research	Performed the experiments	Investigation	YES
5731093	29246115	NR	PLoS52	designed the research|performed the research|contributed new reagents/analytical tools|analysed data|wrote the paper	contributed new reagents/analytical tools	Contributed reagents/materials/analysis tools	Resources	YES
5731093	29246115	NR	PLoS52	designed the research|performed the research|contributed new reagents/analytical tools|analysed data|wrote the paper	analysed data	Analyzed the data	Formal analysis	YES
5731093	29246115	NR	PLoS52	designed the research|performed the research|contributed new reagents/analytical tools|analysed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5731093	29246115	OA	PLoS52	designed the research|performed the research|wrote the paper	designed the research	Conceived and designed the experiments	Methodology	YES
5731093	29246115	OA	PLoS52	designed the research|performed the research|wrote the paper	performed the research	Performed the experiments	Investigation	YES
5731093	29246115	OA	PLoS52	designed the research|performed the research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4650123	26554039	Both authors	2	discussed the topic and wrote the manuscript	discussed the topic and wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
1952108	17786202	AB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1952108	17786202	AB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1952108	17786202	AB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1952108	17786202	GP	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1952108	17786202	GP	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1952108	17786202	GS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1952108	17786202	GS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1952108	17786202	MB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5797535	29441077	C-MR	2	designed the review|wrote the review	designed the review	Conceived and designed the experiments	-	YES
5797535	29441077	C-MR	2	designed the review|wrote the review	wrote the review	Wrote the paper	Writing - Original Draft	YES
5797535	29441077	JJ	2	designed the review|wrote the review	designed the review	Conceived and designed the experiments	-	YES
5797535	29441077	JJ	2	designed the review|wrote the review	wrote the review	Wrote the paper	Writing - Original Draft	YES
5797535	29441077	JK	2	wrote the review	wrote the review	Wrote the paper	Writing - Original Draft	YES
5797535	29441077	M-JJ	2	wrote the review	wrote the review	Wrote the paper	Writing - Original Draft	YES
5797535	29441077	S-KK	2	wrote the review	wrote the review	Wrote the paper	Writing - Original Draft	YES
5793798	29335280	ACD	2	provided supervision	provided supervision	-	Supervision	YES
5793798	29335280	AHK	2	contributed to electrophysiology and analysed the data	contributed to electrophysiology and analysed the data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5793798	29335280	All authors	2	prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5793798	29335280	BMK	2	provided supervision	provided supervision	-	Supervision	YES
5793798	29335280	FZ	2	provided supervision	provided supervision	-	Supervision	YES
5793798	29335280	GB	2	provided supervision	provided supervision	-	Supervision	YES
5793798	29335280	HH	2	performed mass spectrometry and analysed the data	performed mass spectrometry and analysed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5793798	29335280	JEL	2	contributed to electrophysiology and analysed the data	contributed to electrophysiology and analysed the data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5793798	29335280	JJC	2	provided supervision	provided supervision	-	Supervision	YES
5793798	29335280	JNW	2	conceived the study, designed the research and provided supervision	conceived the study, designed the research and provided supervision	Conceived and designed the experiments	Conceptualization|Methodology|Supervision	YES
5793798	29335280	JZ	2	maintained the mouse line|contributed to pain behavioural study and analysed the data|performed immunohistochemistry and analysed the data|conceived the study, designed the research and provided supervision	maintained the mouse line	-	-	NO
5793798	29335280	JZ	2	maintained the mouse line|contributed to pain behavioural study and analysed the data|performed immunohistochemistry and analysed the data|conceived the study, designed the research and provided supervision	contributed to pain behavioural study and analysed the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5793798	29335280	JZ	2	maintained the mouse line|contributed to pain behavioural study and analysed the data|performed immunohistochemistry and analysed the data|conceived the study, designed the research and provided supervision	performed immunohistochemistry and analysed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5793798	29335280	JZ	2	maintained the mouse line|contributed to pain behavioural study and analysed the data|performed immunohistochemistry and analysed the data|conceived the study, designed the research and provided supervision	conceived the study, designed the research and provided supervision	Conceived and designed the experiments	Conceptualization|Methodology|Supervision	YES
5793798	29335280	MP	2	performed immunohistochemistry and analysed the data	performed immunohistochemistry and analysed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5793798	29335280	QM	2	maintained the mouse line|contributed to pain behavioural study and analysed the data	maintained the mouse line	-	-	NO
5793798	29335280	QM	2	maintained the mouse line|contributed to pain behavioural study and analysed the data	contributed to pain behavioural study and analysed the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5793798	29335280	SJG	2	maintained the mouse line	maintained the mouse line	-	-	NO
5793798	29335280	SL	2	contributed to electrophysiology and analysed the data	contributed to electrophysiology and analysed the data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5793798	29335280	TM	2	performed immunohistochemistry and analysed the data	performed immunohistochemistry and analysed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6161438	30261892	EC	PLoS52	designed the study|conducted the study|analysed the data|wrote the paper	designed the study	Conceived and designed the experiments	Methodology	YES
6161438	30261892	EC	PLoS52	designed the study|conducted the study|analysed the data|wrote the paper	conducted the study	Performed the experiments	Investigation	YES
6161438	30261892	EC	PLoS52	designed the study|conducted the study|analysed the data|wrote the paper	analysed the data	Analyzed the data	Formal analysis	YES
6161438	30261892	EC	PLoS52	designed the study|conducted the study|analysed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6161438	30261892	MB	PLoS52	analysed the data|wrote the paper	analysed the data	Analyzed the data	Formal analysis	YES
6161438	30261892	MB	PLoS52	analysed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6161438	30261892	SS	PLoS52	designed the study|analysed the data|wrote the paper|had primary responsibility for the final content	designed the study	Conceived and designed the experiments	Methodology	YES
6161438	30261892	SS	PLoS52	designed the study|analysed the data|wrote the paper|had primary responsibility for the final content	analysed the data	Analyzed the data	Formal analysis	YES
6161438	30261892	SS	PLoS52	designed the study|analysed the data|wrote the paper|had primary responsibility for the final content	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6161438	30261892	SS	PLoS52	designed the study|analysed the data|wrote the paper|had primary responsibility for the final content	had primary responsibility for the final content	-	-	NO
6161438	30261892	YM	PLoS52	designed the study|conducted the study|analysed the data	designed the study	Conceived and designed the experiments	Methodology	YES
6161438	30261892	YM	PLoS52	designed the study|conducted the study|analysed the data	conducted the study	Performed the experiments	Investigation	YES
6161438	30261892	YM	PLoS52	designed the study|conducted the study|analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
6270661	24473204	All authors	2	helped preparing the manuscript and approved the final version	helped preparing the manuscript and approved the final version	Wrote the paper	Writing - Original Draft	YES
6270661	24473204	Banasri Hazra	2	contributed with valuable discussions and scientific input	contributed with valuable discussions and scientific input	-	-	NO
6270661	24473204	Heidrun Moll	2	contributed with valuable discussions and scientific input	contributed with valuable discussions and scientific input	-	-	NO
6270661	24473204	Jan Glaser	2	fractionated the plant extract and isolated and identified the antileishmanial compound|also carried out the synthesis and prepared the manuscript	fractionated the plant extract and isolated and identified the antileishmanial compound	Performed the experiments	Investigation	YES
6270661	24473204	Jan Glaser	2	fractionated the plant extract and isolated and identified the antileishmanial compound|also carried out the synthesis and prepared the manuscript	also carried out the synthesis and prepared the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6270661	24473204	Ulrike Holzgrabe	2	proposed the subject and monitored the progress of the ongoing research|contributed with valuable discussions and scientific input	proposed the subject and monitored the progress of the ongoing research	Conceived and designed the experiments	Conceptualization|Supervision	YES
6270661	24473204	Ulrike Holzgrabe	2	proposed the subject and monitored the progress of the ongoing research|contributed with valuable discussions and scientific input	contributed with valuable discussions and scientific input	-	-	NO
5797538	29441084	FY	2	performed the experiment|conceived the original research plans|designed the experiments, analyzed the data, and wrote the article	performed the experiment	Performed the experiments	Investigation	YES
5797538	29441084	FY	2	performed the experiment|conceived the original research plans|designed the experiments, analyzed the data, and wrote the article	conceived the original research plans	Conceived and designed the experiments	Conceptualization	YES
5797538	29441084	FY	2	performed the experiment|conceived the original research plans|designed the experiments, analyzed the data, and wrote the article	designed the experiments, analyzed the data, and wrote the article	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5797538	29441084	JC	2	performed some experiments	performed some experiments	Performed the experiments	Investigation	YES
5797538	29441084	JD	2	conceived the original research plans	conceived the original research plans	Conceived and designed the experiments	Conceptualization	YES
5797538	29441084	JL	2	conceived the original research plans	conceived the original research plans	Conceived and designed the experiments	Conceptualization	YES
5797538	29441084	KS	2	conceived the original research plans	conceived the original research plans	Conceived and designed the experiments	Conceptualization	YES
5797538	29441084	LF	2	performed some experiments	performed some experiments	Performed the experiments	Investigation	YES
5797538	29441084	QL	2	performed the experiment	performed the experiment	Performed the experiments	Investigation	YES
5797538	29441084	TY	2	conceived the original research plans	conceived the original research plans	Conceived and designed the experiments	Conceptualization	YES
5797538	29441084	WL	2	conceived the original research plans	conceived the original research plans	Conceived and designed the experiments	Conceptualization	YES
5797538	29441084	WY	2	conceived the original research plans|designed the experiments, analyzed the data, and wrote the article	conceived the original research plans	Conceived and designed the experiments	Conceptualization	YES
5797538	29441084	WY	2	conceived the original research plans|designed the experiments, analyzed the data, and wrote the article	designed the experiments, analyzed the data, and wrote the article	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5797538	29441084	XWa	2	conceived the original research plans	conceived the original research plans	Conceived and designed the experiments	Conceptualization	YES
5797538	29441084	XWu	2	performed the experiment	performed the experiment	Performed the experiments	Investigation	YES
5797538	29441084	YC	2	performed the experiment	performed the experiment	Performed the experiments	Investigation	YES
5797538	29441084	YF	2	performed the experiment	performed the experiment	Performed the experiments	Investigation	YES
5797538	29441084	ZW	2	performed some experiments	performed some experiments	Performed the experiments	Investigation	YES
1952109	17786214	AM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1952109	17786214	AM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1952109	17786214	AM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1952109	17786214	EG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1952109	17786214	EG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1952109	17786214	EG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1952109	17786214	YA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1952109	17786214	YA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1952109	17786214	YA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1952109	17786214	YA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1952109	17786214	YA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1952109	17786214	YB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1952109	17786214	YB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1952109	17786214	YB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1952109	17786214	YB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1952109	17786214	YL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5500597	28687037	Both authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5500597	28687037	Discovery Science	2	in canada	in canada	-	-	NO
5500597	28687037	The authors	2	contributed equally to this article|declare that they have no competing interests	contributed equally to this article	-	-	NO
5500597	28687037	The authors	2	contributed equally to this article|declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5731188	29246110	CC	2	helped with the performed most of the bioinformatic and statistical analyses with	helped with the performed most of the bioinformatic and statistical analyses with	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5731188	29246110	KT	2	helped with the performed most of the bioinformatic and statistical analyses with	helped with the performed most of the bioinformatic and statistical analyses with	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5731188	29246110	MDL	2	conceived of the study and experiments|were involved in supervision of the project|wrote the manuscript	conceived of the study and experiments	Conceived and designed the experiments	Conceptualization	YES
5731188	29246110	MDL	2	conceived of the study and experiments|were involved in supervision of the project|wrote the manuscript	were involved in supervision of the project	-	Supervision	YES
5731188	29246110	MDL	2	conceived of the study and experiments|were involved in supervision of the project|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5731188	29246110	MK	2	helped with the performed most of the bioinformatic and statistical analyses with	helped with the performed most of the bioinformatic and statistical analyses with	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5731188	29246110	MS	2	helped with the performed most of the bioinformatic and statistical analyses with	helped with the performed most of the bioinformatic and statistical analyses with	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5731188	29246110	RGS	2	conceived of the study and experiments|were involved in supervision of the project	conceived of the study and experiments	Conceived and designed the experiments	Conceptualization	YES
5731188	29246110	RGS	2	conceived of the study and experiments|were involved in supervision of the project	were involved in supervision of the project	-	Supervision	YES
5731188	29246110	RJS	2	were involved in supervision of the project	were involved in supervision of the project	-	Supervision	YES
5731188	29246110	RS	2	helped with the performed most of the bioinformatic and statistical analyses with	helped with the performed most of the bioinformatic and statistical analyses with	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5731188	29246110	SRD	2	conceived of the study and experiments|were involved in supervision of the project	conceived of the study and experiments	Conceived and designed the experiments	Conceptualization	YES
5731188	29246110	SRD	2	conceived of the study and experiments|were involved in supervision of the project	were involved in supervision of the project	-	Supervision	YES
5731188	29246110	TJJJ	2	helped with the performed most of the bioinformatic and statistical analyses with	helped with the performed most of the bioinformatic and statistical analyses with	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5731188	29246110	TJL	2	performed most of the bioinformatic and statistical analyses with|conceived of the study and experiments|wrote the manuscript	performed most of the bioinformatic and statistical analyses with	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5731188	29246110	TJL	2	performed most of the bioinformatic and statistical analyses with|conceived of the study and experiments|wrote the manuscript	conceived of the study and experiments	Conceived and designed the experiments	Conceptualization	YES
5731188	29246110	TJL	2	performed most of the bioinformatic and statistical analyses with|conceived of the study and experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4650127	26554043	F.H.	5	conceived and wrote the paper with contributions from N	conceived and wrote the paper with contributions from N	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4650127	26554043	V.G.F.	5	conceived and wrote the paper with contributions from N	conceived and wrote the paper with contributions from N	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4416745	25932639	JRH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416745	25932639	JRH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416745	25932639	JRH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416745	25932639	KK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416745	25932639	KK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416745	25932639	KK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416745	25932639	KK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416745	25932639	TLA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416745	25932639	TLA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416745	25932639	TLA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6172780	30286760	AM-G	PLoS52	performed the experiments|contributed reagents/materials/analysis tools	performed the experiments	Performed the experiments	Investigation	YES
6172780	30286760	AM-G	PLoS52	performed the experiments|contributed reagents/materials/analysis tools	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
6172780	30286760	EC	PLoS52	performed the experiments|contributed reagents/materials/analysis tools	performed the experiments	Performed the experiments	Investigation	YES
6172780	30286760	EC	PLoS52	performed the experiments|contributed reagents/materials/analysis tools	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
6172780	30286760	GP-S	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
6172780	30286760	GP-S	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
6172780	30286760	JLM-M	PLoS52	conceived and designed the experiments|analyzed the data|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6172780	30286760	JLM-M	PLoS52	conceived and designed the experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
6172780	30286760	JLM-M	PLoS52	conceived and designed the experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6172780	30286760	MCL-E	PLoS52	performed the experiments|contributed reagents/materials/analysis tools	performed the experiments	Performed the experiments	Investigation	YES
6172780	30286760	MCL-E	PLoS52	performed the experiments|contributed reagents/materials/analysis tools	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
6172780	30286760	MVG-C	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6172780	30286760	MVG-C	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
6172780	30286760	MVG-C	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
6172780	30286760	MVG-C	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6172780	30286760	PG-F	PLoS52	performed the experiments|contributed reagents/materials/analysis tools	performed the experiments	Performed the experiments	Investigation	YES
6172780	30286760	PG-F	PLoS52	performed the experiments|contributed reagents/materials/analysis tools	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
6172780	30286760	PV-H	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
6172780	30286760	RD	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6172780	30286760	RD	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
6172780	30286760	RD	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
6172780	30286760	RD	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270662	24879585	A.C.A.S.	2	effected the cytotoxicity assays and participated on the writing of manuscript	effected the cytotoxicity assays and participated on the writing of manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6270662	24879585	A.M.D.C.F.	2	registered the epr spectra and participated on the writing of manuscript	registered the epr spectra and participated on the writing of manuscript	Wrote the paper	Writing - Original Draft	YES
6270662	24879585	C.V.B.M.	2	effected the antifungal assays and participated on the writing of manuscript	effected the antifungal assays and participated on the writing of manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6270662	24879585	L.J.N.	2	synthesized all ligands and complexes and participated in all steps of the research	synthesized all ligands and complexes and participated in all steps of the research	Performed the experiments	Investigation	YES
6270662	24879585	M.A.R.S.	2	effected the antifungal assays and participated on the writing of manuscript	effected the antifungal assays and participated on the writing of manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6270662	24879585	M.H.A.	2	helped a lot in the complexes characterization and participated on the writing of manuscript	helped a lot in the complexes characterization and participated on the writing of manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6270662	24879585	M.T.P.L.	2	effected the cytotoxicity assays and participated on the writing of manuscript	effected the cytotoxicity assays and participated on the writing of manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6270662	24879585	S.R.O.	2	registered the esi-ms spectra and participated on the writing of manuscript	registered the esi-ms spectra and participated on the writing of manuscript	Wrote the paper	Writing - Original Draft	YES
6270662	24879585	T.F.F.M.	2	effected the antifungal assays and participated on the writing of manuscript	effected the antifungal assays and participated on the writing of manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5793800	29311115	All authors	2	critically read and approved the submitted manuscript	critically read and approved the submitted manuscript	-	-	NO
5793800	29311115	CC-C	2	designed experiments|performed experiments and analysed the data	designed experiments	Conceived and designed the experiments	Methodology	YES
5793800	29311115	CC-C	2	designed experiments|performed experiments and analysed the data	performed experiments and analysed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5793800	29311115	DFS	2	developed analytical tools	developed analytical tools	-	-	NO
5793800	29311115	DI	2	designed experiments|performed experiments and analysed the data	designed experiments	Conceived and designed the experiments	Methodology	YES
5793800	29311115	DI	2	designed experiments|performed experiments and analysed the data	performed experiments and analysed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5793800	29311115	EFH	2	designed experiments|performed experiments and analysed the data	designed experiments	Conceived and designed the experiments	Methodology	YES
5793800	29311115	EFH	2	designed experiments|performed experiments and analysed the data	performed experiments and analysed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5793800	29311115	GL-D	2	conceived and designed the project|designed experiments|performed experiments and analysed the data|wrote the manuscript	conceived and designed the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5793800	29311115	GL-D	2	conceived and designed the project|designed experiments|performed experiments and analysed the data|wrote the manuscript	designed experiments	Conceived and designed the experiments	Methodology	YES
5793800	29311115	GL-D	2	conceived and designed the project|designed experiments|performed experiments and analysed the data|wrote the manuscript	performed experiments and analysed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5793800	29311115	GL-D	2	conceived and designed the project|designed experiments|performed experiments and analysed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5793800	29311115	JTK	2	conceived and designed the project|designed experiments|wrote the manuscript|supervised the project	conceived and designed the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5793800	29311115	JTK	2	conceived and designed the project|designed experiments|wrote the manuscript|supervised the project	designed experiments	Conceived and designed the experiments	Methodology	YES
5793800	29311115	JTK	2	conceived and designed the project|designed experiments|wrote the manuscript|supervised the project	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5793800	29311115	JTK	2	conceived and designed the project|designed experiments|wrote the manuscript|supervised the project	supervised the project	-	Supervision	YES
5793800	29311115	NB	2	performed experiments and analysed the data	performed experiments and analysed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5793800	29311115	RN	2	performed experiments and analysed the data	performed experiments and analysed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
1952110	17786225	AK	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1952110	17786225	AK	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1952110	17786225	GG	PLoS5	Designed and generated n-terminal deletion construct	Designed and generated n-terminal deletion construct	Conceived and designed the experiments|Performed the experiments	Investigation	YES
1952110	17786225	SC	PLoS5	Designed and generated n-terminal deletion construct	Designed and generated n-terminal deletion construct	Conceived and designed the experiments|Performed the experiments	Investigation	YES
1952110	17786225	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1952110	17786225	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1952110	17786225	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1952110	17786225	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5797549	29441078	HP	2	collected the plant materials and measured leaf traits|provided suggestions for revision	collected the plant materials and measured leaf traits	Performed the experiments	Investigation	YES
5797549	29441078	HP	2	collected the plant materials and measured leaf traits|provided suggestions for revision	provided suggestions for revision	Wrote the paper	Writing - Review & Editing	YES
5797549	29441078	JW	2	collected the plant materials and measured leaf traits|provided suggestions for revision	collected the plant materials and measured leaf traits	Performed the experiments	Investigation	YES
5797549	29441078	JW	2	collected the plant materials and measured leaf traits|provided suggestions for revision	provided suggestions for revision	Wrote the paper	Writing - Review & Editing	YES
5797549	29441078	KM	2	designed the experiments|performed and analyzed the molecular markers test|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5797549	29441078	KM	2	designed the experiments|performed and analyzed the molecular markers test|wrote the manuscript	performed and analyzed the molecular markers test	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5797549	29441078	KM	2	designed the experiments|performed and analyzed the molecular markers test|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5797549	29441078	LS	2	collected the plant materials and measured leaf traits|provided suggestions for revision	collected the plant materials and measured leaf traits	Performed the experiments	Investigation	YES
5797549	29441078	LS	2	collected the plant materials and measured leaf traits|provided suggestions for revision	provided suggestions for revision	Wrote the paper	Writing - Review & Editing	YES
5797549	29441078	QZ	2	designed the experiments|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5797549	29441078	QZ	2	designed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5797549	29441078	TC	2	collected the plant materials and measured leaf traits|provided suggestions for revision	collected the plant materials and measured leaf traits	Performed the experiments	Investigation	YES
5797549	29441078	TC	2	collected the plant materials and measured leaf traits|provided suggestions for revision	provided suggestions for revision	Wrote the paper	Writing - Review & Editing	YES
4416747	25933027	KXS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416747	25933027	SC	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4416747	25933027	SC	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4416747	25933027	SC	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416747	25933027	XC	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416747	25933027	XC	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416747	25933027	YLX	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416747	25933027	YZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416747	25933027	YZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416747	25933027	YZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4650129	26554045	E.D.J.	2	conceived and wrote the paper	conceived and wrote the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4650129	26554045	M.C.	2	conceived and wrote the paper	conceived and wrote the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5500603	28687036	AL	2	carried out the experiments|reviewed the manuscript	carried out the experiments	Performed the experiments	Investigation	YES
5500603	28687036	AL	2	carried out the experiments|reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5500603	28687036	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5500603	28687036	CH	2	planned the experiments, analyzed the data and wrote the manuscript	planned the experiments, analyzed the data and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
5500603	28687036	DK	2	planned the experiments, analyzed the data and wrote the manuscript|carried out the experiments	planned the experiments, analyzed the data and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
5500603	28687036	DK	2	planned the experiments, analyzed the data and wrote the manuscript|carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5500603	28687036	ML	2	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5500603	28687036	SP	2	planned the experiments, analyzed the data and wrote the manuscript	planned the experiments, analyzed the data and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
5500603	28687036	WN	2	carried out the experiments|reviewed the manuscript	carried out the experiments	Performed the experiments	Investigation	YES
5500603	28687036	WN	2	carried out the experiments|reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
6196563	30348185	All authors	2	critically reviewed the draft and approved the final manuscript	critically reviewed the draft and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6196563	30348185	KS	2	designed the study|interpreted results and wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
6196563	30348185	KS	2	designed the study|interpreted results and wrote the manuscript	interpreted results and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6196563	30348185	KVA	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
6196563	30348185	MRK	2	was the principal investigator and conducted the clinical trial	was the principal investigator and conducted the clinical trial	Conceived and designed the experiments|Performed the experiments	Conceptualization|Funding acquisition|Investigation	YES
6196563	30348185	PKJ	2	undertook the management of the trial including quality assurance and the data collection	undertook the management of the trial including quality assurance and the data collection	Performed the experiments|Analyzed the data	Data curation|Investigation|Project administration|Validation	YES
6196563	30348185	TG	2	was primarily responsible for standardization and quality assurance of the investigational product	was primarily responsible for standardization and quality assurance of the investigational product	Performed the experiments	Investigation|Validation	YES
1952140	17786217	BS	CRediT	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Supervision|Reviewing|Developed the study design|Helped with the analysis of the data|Helped with the manuscript writing	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1952140	17786217	BS	CRediT	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Supervision|Reviewing|Developed the study design|Helped with the analysis of the data|Helped with the manuscript writing	Analyzed the data	Analyzed the data	Formal analysis	YES
1952140	17786217	BS	CRediT	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Supervision|Reviewing|Developed the study design|Helped with the analysis of the data|Helped with the manuscript writing	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1952140	17786217	BS	CRediT	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Supervision|Reviewing|Developed the study design|Helped with the analysis of the data|Helped with the manuscript writing	Supervision	-	Supervision	YES
1952140	17786217	BS	CRediT	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Supervision|Reviewing|Developed the study design|Helped with the analysis of the data|Helped with the manuscript writing	Reviewing	-	-	NO
1952140	17786217	BS	CRediT	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Supervision|Reviewing|Developed the study design|Helped with the analysis of the data|Helped with the manuscript writing	Developed the study design	Conceived and designed the experiments	Methodology	YES
1952140	17786217	BS	CRediT	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Supervision|Reviewing|Developed the study design|Helped with the analysis of the data|Helped with the manuscript writing	Helped with the analysis of the data	Analyzed the data	Formal analysis	YES
1952140	17786217	BS	CRediT	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Supervision|Reviewing|Developed the study design|Helped with the analysis of the data|Helped with the manuscript writing	Helped with the manuscript writing	Wrote the paper	Writing - Original Draft	YES
1952140	17786217	HB	CRediT	Contributed reagents/materials/analysis tools|Main supervisor of the master thesis|Reviewing|Provided all necessary know-how and support|Support in lab	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1952140	17786217	HB	CRediT	Contributed reagents/materials/analysis tools|Main supervisor of the master thesis|Reviewing|Provided all necessary know-how and support|Support in lab	Main supervisor of the master thesis	-	Supervision	YES
1952140	17786217	HB	CRediT	Contributed reagents/materials/analysis tools|Main supervisor of the master thesis|Reviewing|Provided all necessary know-how and support|Support in lab	Reviewing	-	-	NO
1952140	17786217	HB	CRediT	Contributed reagents/materials/analysis tools|Main supervisor of the master thesis|Reviewing|Provided all necessary know-how and support|Support in lab	Provided all necessary know-how and support	-	-	NO
1952140	17786217	HB	CRediT	Contributed reagents/materials/analysis tools|Main supervisor of the master thesis|Reviewing|Provided all necessary know-how and support|Support in lab	Support in lab	-	-	NO
1952140	17786217	SZ	CRediT	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1952140	17786217	SZ	CRediT	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1952140	17786217	SZ	CRediT	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1952140	17786217	SZ	CRediT	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270663	24686577	H. Aoyama	2	contributed to the ms measurements and interpretation of those spectra	contributed to the ms measurements and interpretation of those spectra	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270663	24686577	M. A. A. Orabi	2	contributed to checking and confirming all of the procedures of the isolation and structural identification, especially interpretation of the nmr spectra, and also to preparing the manuscript	contributed to checking and confirming all of the procedures of the isolation and structural identification, especially interpretation of the nmr spectra, and also to preparing the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
6270663	24686577	T. Hatano	2	the corresponding author	the corresponding author	-	-	NO
6270663	24686577	T. Kuroda	2	contributed to the antibacterial experiments	contributed to the antibacterial experiments	Performed the experiments	Investigation	YES
5731206	29246116	DR	2	designed and carried out experimental work, acquired, analysed and interpreted data and contributed to drafting the manuscript	designed and carried out experimental work, acquired, analysed and interpreted data and contributed to drafting the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5731206	29246116	GH	2	acquired, analysed and interpreted data and revised the manuscript	acquired, analysed and interpreted data and revised the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
5731206	29246116	LBS	2	conceived and designed the overall study, analysed and interpreted data and drafted the manuscript	conceived and designed the overall study, analysed and interpreted data and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
5731206	29246116	MHA	2	acquired, analysed and interpreted data and revised the manuscript	acquired, analysed and interpreted data and revised the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
5731206	29246116	PAF	2	analysed and interpreted data and revised the manuscript	analysed and interpreted data and revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5731206	29246116	PJOS	2	conceived and designed the overall study, analysed and interpreted data and drafted the manuscript	conceived and designed the overall study, analysed and interpreted data and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
5731206	29246116	SL	2	acquired, analysed and interpreted data and revised the manuscript	acquired, analysed and interpreted data and revised the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
5731206	29246116	US	2	designed and carried out experimental work, acquired, analysed and interpreted data and contributed to drafting the manuscript	designed and carried out experimental work, acquired, analysed and interpreted data and contributed to drafting the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5813253	29255010	HS	2	provided support with and supervised data collection	provided support with and supervised data collection	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources|Supervision	YES
5813253	29255010	JPS	2	isolated and purified sheaths from hcp-limited cells and performed ms data collection and analysis|performed imaging and image processing of hcp-limited cells	isolated and purified sheaths from hcp-limited cells and performed ms data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5813253	29255010	JPS	2	isolated and purified sheaths from hcp-limited cells and performed ms data collection and analysis|performed imaging and image processing of hcp-limited cells	performed imaging and image processing of hcp-limited cells	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
5813253	29255010	KNG	2	provided support with and supervised data collection	provided support with and supervised data collection	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources|Supervision	YES
5813253	29255010	MBa	2	conceived the project and analyzed the data|wrote the manuscript	conceived the project and analyzed the data	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
5813253	29255010	MBa	2	conceived the project and analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5813253	29255010	MBr	2	isolated and purified the sheaths and contributed to data collection and analysis	isolated and purified the sheaths and contributed to data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5813253	29255010	SN	2	collected electron microscopy data, performed image processing, and data analysis|wrote the manuscript	collected electron microscopy data, performed image processing, and data analysis	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation|Visualization	YES
5813253	29255010	SN	2	collected electron microscopy data, performed image processing, and data analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5797552	29441087	BZ	2	performed research and analyzed data	performed research and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5797552	29441087	DW	2	designed research and wrote the paper|performed research and analyzed data	designed research and wrote the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5797552	29441087	DW	2	designed research and wrote the paper|performed research and analyzed data	performed research and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5797552	29441087	MD	2	performed research and analyzed data	performed research and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4650132	26554048	All authors	2	wrote and approved the manuscript together	wrote and approved the manuscript together	Wrote the paper	Writing - Original Draft	YES
4650132	26554048	I.K.	2	prepared the figures	prepared the figures	-	Visualization	YES
6198523	30348178	All authors	2	participated at the conception and design of the study|participated at data interpretation and analysis	participated at the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6198523	30348178	All authors	2	participated at the conception and design of the study|participated at data interpretation and analysis	participated at data interpretation and analysis	Analyzed the data	Formal analysis	YES
6198523	30348178	HLS	2	were involved at data collection	were involved at data collection	Performed the experiments	Investigation	YES
6198523	30348178	JMC	2	participated at manuscript drafting	participated at manuscript drafting	Wrote the paper	Writing - Original Draft	YES
6198523	30348178	KFV	2	participated at manuscript drafting	participated at manuscript drafting	Wrote the paper	Writing - Original Draft	YES
6198523	30348178	LCC	2	were involved at data collection	were involved at data collection	Performed the experiments	Investigation	YES
6198523	30348178	LG-F	2	were involved at data collection|participated at manuscript drafting	were involved at data collection	Performed the experiments	Investigation	YES
6198523	30348178	LG-F	2	were involved at data collection|participated at manuscript drafting	participated at manuscript drafting	Wrote the paper	Writing - Original Draft	YES
6198523	30348178	MAGJr	2	were involved at data collection|participated at manuscript drafting	were involved at data collection	Performed the experiments	Investigation	YES
6198523	30348178	MAGJr	2	were involved at data collection|participated at manuscript drafting	participated at manuscript drafting	Wrote the paper	Writing - Original Draft	YES
6198523	30348178	MJD	2	participated at manuscript drafting	participated at manuscript drafting	Wrote the paper	Writing - Original Draft	YES
5500604	28687035	AA	2	contributed in the examinations and data collection	contributed in the examinations and data collection	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5500604	28687035	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5500604	28687035	FA	2	conducted the research and wrote the manuscript	conducted the research and wrote the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5500604	28687035	HP	2	conducted the research and wrote the manuscript	conducted the research and wrote the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5500604	28687035	JS	2	contributed in the examinations and data collection	contributed in the examinations and data collection	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5500604	28687035	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5500604	28687035	VJ	2	contributed in the examinations and data collection	contributed in the examinations and data collection	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4416749	25933135	BL	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416749	25933135	BL	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416749	25933135	HH	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416749	25933135	HH	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416749	25933135	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416749	25933135	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416749	25933135	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416749	25933135	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416749	25933135	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1952141	17786218	AF	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1952141	17786218	AG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1952141	17786218	GM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1952141	17786218	GM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1952141	17786218	GM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1952141	17786218	GM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1952141	17786218	GM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1952141	17786218	JA	PLoS5	Analyzed the data|Developed software	Analyzed the data	Analyzed the data	Formal analysis	YES
1952141	17786218	JA	PLoS5	Analyzed the data|Developed software	Developed software	Contributed reagents/materials/analysis tools	Software	YES
1952141	17786218	JO	PLoS5	Conceived and designed the experiments|Analyzed the data|Developed software	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1952141	17786218	JO	PLoS5	Conceived and designed the experiments|Analyzed the data|Developed software	Analyzed the data	Analyzed the data	Formal analysis	YES
1952141	17786218	JO	PLoS5	Conceived and designed the experiments|Analyzed the data|Developed software	Developed software	Contributed reagents/materials/analysis tools	Software	YES
1952141	17786218	LC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1952141	17786218	MP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Developed software	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1952141	17786218	MP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Developed software	Performed the experiments	Performed the experiments	Investigation	YES
1952141	17786218	MP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Developed software	Analyzed the data	Analyzed the data	Formal analysis	YES
1952141	17786218	MP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Developed software	Developed software	Contributed reagents/materials/analysis tools	Software	YES
1952141	17786218	MS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1952141	17786218	MS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270664	25514226	LA	PLoS52	designed research|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
6270664	25514226	LA	PLoS52	designed research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270664	25514226	LH	PLoS52	designed research|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
6270664	25514226	LH	PLoS52	designed research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270664	25514226	YT	PLoS52	analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
6270664	25514226	YT	PLoS52	analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270664	25514226	ZQ	PLoS52	designed research|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
6270664	25514226	ZQ	PLoS52	designed research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6204040	30367639	CPL	2	is solely responsible for the content of this manuscript	is solely responsible for the content of this manuscript	-	-	NO
5731209	29246191	All authors	2	assisted with writing the manuscript	assisted with writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5731209	29246191	GLC	2	conceived of the study|analyzed the data and wrote the manuscript	conceived of the study	Conceived and designed the experiments	Conceptualization	YES
5731209	29246191	GLC	2	conceived of the study|analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5731209	29246191	JCD	2	provided ancestry proportion data and produced map figures	provided ancestry proportion data and produced map figures	Contributed reagents/materials/analysis tools	Resources|Visualization	YES
5731209	29246191	KAH	2	generated the snp genotypes|conducted nucleotide diversity analyses	generated the snp genotypes	Performed the experiments	Investigation	YES
5731209	29246191	KAH	2	generated the snp genotypes|conducted nucleotide diversity analyses	conducted nucleotide diversity analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5731209	29246191	LHR	2	conceived of the study	conceived of the study	Conceived and designed the experiments	Conceptualization	YES
5731209	29246191	MCW	2	conceived of the study	conceived of the study	Conceived and designed the experiments	Conceptualization	YES
5731209	29246191	SNA	2	conceived of the study	conceived of the study	Conceived and designed the experiments	Conceptualization	YES
5731209	29246191	SY	2	generated the snp genotypes	generated the snp genotypes	Performed the experiments	Investigation	YES
5503846	28697587	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5503846	28697587	HYY	2	designed the work, synthesized the probe, performed purified enzyme study and wrote the draft manuscript	designed the work, synthesized the probe, performed purified enzyme study and wrote the draft manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5503846	28697587	JIH	2	supervised the research and wrote the manuscript	supervised the research and wrote the manuscript	Wrote the paper	Supervision|Writing - Original Draft	YES
5503846	28697587	SJ	2	guided and participated in the bacterial study	guided and participated in the bacterial study	-	Supervision	YES
5503846	28697587	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5813257	29317426	EJ	2	performed and analysed experiments	performed and analysed experiments	Performed the experiments	Investigation	YES
5813257	29317426	JMA	2	designed and made the e230 mouse	designed and made the e230 mouse	Conceived and designed the experiments	-	YES
5813257	29317426	KF	2	designed performed and analysed experiments	designed performed and analysed experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5813257	29317426	NG	2	provided essential reagents and reviewed the manuscript	provided essential reagents and reviewed the manuscript	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Review & Editing	YES
5813257	29317426	OF	2	designed experiments and wrote the paper	designed experiments and wrote the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5813257	29317426	RB	2	designed experiments and wrote the paper	designed experiments and wrote the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5813257	29317426	RU	2	designed performed and analysed experiments	designed performed and analysed experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5813257	29317426	SC	2	provided financial and intellectual input	provided financial and intellectual input	-	-	NO
5813257	29317426	TV	2	performed and analysed experiments	performed and analysed experiments	Performed the experiments	Investigation	YES
5813257	29317426	TW	2	designed experiments	designed experiments	Conceived and designed the experiments	Methodology	YES
5813257	29317426	UM	2	designed and made the e230 mouse	designed and made the e230 mouse	Conceived and designed the experiments	-	YES
5797596	29441085	J-FL	2	designed and revised the manuscript	designed and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Review & Editing	YES
5797596	29441085	JJ	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5797596	29441085	JW	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5797596	29441085	XC	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5797596	29441085	XJ	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5797596	29441085	XW	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5797596	29441085	YZ	2	wrote the manuscript|designed and revised the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5797596	29441085	YZ	2	wrote the manuscript|designed and revised the manuscript	designed and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Review & Editing	YES
1952142	17786198	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1952142	17786198	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1952142	17786198	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1952142	17786198	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1952142	17786198	CW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1952142	17786198	CW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1952142	17786198	DB	PLoS5	Helped conceive and design the experiments, specifically the study protocol	Helped conceive and design the experiments, specifically the study protocol	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
1952142	17786198	DG	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1952142	17786198	DG	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1952142	17786198	DG	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1952142	17786198	GS	PLoS5	Contributed reagents/materials/analysis tools|Provided logistical support	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1952142	17786198	GS	PLoS5	Contributed reagents/materials/analysis tools|Provided logistical support	Provided logistical support	-	-	NO
1952142	17786198	JS	PLoS5	Contributed reagents/materials/analysis tools|Provided logistical support	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1952142	17786198	JS	PLoS5	Contributed reagents/materials/analysis tools|Provided logistical support	Provided logistical support	-	-	NO
1952142	17786198	KL	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1952142	17786198	LJ	PLoS5	Helped perform the experiments specifically with the patient record abstraction|Helped train the remaining data abstractors in the team	Helped perform the experiments specifically with the patient record abstraction	Performed the experiments	Investigation	YES
1952142	17786198	LJ	PLoS5	Helped perform the experiments specifically with the patient record abstraction|Helped train the remaining data abstractors in the team	Helped train the remaining data abstractors in the team	-	-	NO
1952142	17786198	MM	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1952142	17786198	PP	PLoS5	Contributed reagents/materials/analysis tools|Provided logistical support|Provided administrative support	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1952142	17786198	PP	PLoS5	Contributed reagents/materials/analysis tools|Provided logistical support|Provided administrative support	Provided logistical support	-	-	NO
1952142	17786198	PP	PLoS5	Contributed reagents/materials/analysis tools|Provided logistical support|Provided administrative support	Provided administrative support	-	Project administration	YES
4650134	26554050	All authors	2	contributed to developing ideas and to revising the manuscript, and gave final approval for publication	contributed to developing ideas and to revising the manuscript, and gave final approval for publication	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
4650134	26554050	D.A.	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4650134	26554050	E.B.-G.	2	contributed original data	contributed original data	Contributed reagents/materials/analysis tools	Resources	YES
4650134	26554050	H.M.	2	contributed original data	contributed original data	Contributed reagents/materials/analysis tools	Resources	YES
4416750	25933380	BP	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416750	25933380	BP	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416750	25933380	GB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416750	25933380	GP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416750	25933380	IA	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416750	25933380	MEM	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416750	25933380	MSB	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416750	25933380	NAA	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416750	25933380	PB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416750	25933380	PP	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416750	25933380	TK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416750	25933380	TK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416750	25933380	TK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416750	25933380	ZS	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5731210	29246190	HB	2	conceived and designed the experiment and supervised all analysis and drafted the manuscript	conceived and designed the experiment and supervised all analysis and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Supervision|Writing - Original Draft	YES
5731210	29246190	MY	2	helped with analysis and edited the manuscript	helped with analysis and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5731210	29246190	NU	2	performed the experiment and drafted the manuscript	performed the experiment and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5731210	29246190	ZNOG	2	helped with analysis and edited the manuscript	helped with analysis and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
4628997	26558282	E. Vingard	2	participated in analysis and interpretation of data and in drafting and revising the paper	participated in analysis and interpretation of data and in drafting and revising the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
4628997	26558282	Eva L. Bergsten	2	contributed to the design of the study, carried out the data collection, participated in data analysis, and was mainly responsible for drafting the paper	contributed to the design of the study, carried out the data collection, participated in data analysis, and was mainly responsible for drafting the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
4628997	26558282	S. E. Mathiassen	2	contributed to the design of the study, participated in data analysis and data interpretation, and contributed in drafting and revising the manuscript	contributed to the design of the study, participated in data analysis and data interpretation, and contributed in drafting and revising the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5503847	28697582	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5503847	28697582	CB	2	provided the primary written material and performed the data analysis in this article and was the lead investigator on this work	provided the primary written material and performed the data analysis in this article and was the lead investigator on this work	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
5503847	28697582	CD-K	2	provided some supporting data	provided some supporting data	Contributed reagents/materials/analysis tools	Resources	YES
5503847	28697582	CP	2	was co-investigator in this work	was co-investigator in this work	-	-	NO
5503847	28697582	KS-W	2	collected the raw data used in this paper and provided some data analysis and written contributions	collected the raw data used in this paper and provided some data analysis and written contributions	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft	YES
5503847	28697582	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5503847	28697582	VS	2	performed the analysis of sequencing data	performed the analysis of sequencing data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5813259	29351913	AB	2	generated insect-purified recombinant proteins	generated insect-purified recombinant proteins	Performed the experiments	Investigation	YES
5813259	29351913	AGV	2	designed experiments, analysed data and wrote the manuscript|conducted experiments with	designed experiments, analysed data and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5813259	29351913	AGV	2	designed experiments, analysed data and wrote the manuscript|conducted experiments with	conducted experiments with	Performed the experiments	Investigation	YES
5813259	29351913	CRS	2	designed experiments, analysed data and wrote the manuscript|supervised the project	designed experiments, analysed data and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5813259	29351913	CRS	2	designed experiments, analysed data and wrote the manuscript|supervised the project	supervised the project	-	Supervision	YES
5813259	29351913	JMS	2	assisted with the conducted experiments with	assisted with the conducted experiments with	Performed the experiments	Investigation	YES
5813259	29351913	PVM	2	assisted with the conducted experiments with	assisted with the conducted experiments with	Performed the experiments	Investigation	YES
5813259	29351913	SAL	2	assisted with the conducted experiments with	assisted with the conducted experiments with	Performed the experiments	Investigation	YES
5813259	29351913	SD-G	2	provided key reagents	provided key reagents	Contributed reagents/materials/analysis tools	Resources	YES
5813259	29351913	SK	2	generated insect-purified recombinant proteins	generated insect-purified recombinant proteins	Performed the experiments	Investigation	YES
1952172	17786220	DT	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1952172	17786220	FC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1952172	17786220	FC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1952172	17786220	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1952172	17786220	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1952172	17786220	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1952172	17786220	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1952172	17786220	MF	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1952172	17786220	MF	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1952172	17786220	MK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1952172	17786220	NB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1952172	17786220	NB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1952172	17786220	NB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1952172	17786220	NL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1952172	17786220	NL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1952172	17786220	OG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1952172	17786220	ST	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1952172	17786220	ST	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5797603	29441088	All authors	2	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
6270666	24979399	C.F.C.	7	chemical synthesis	chemical synthesis	-	-	NO
6270666	24979399	L.Y.C.	7	project design and co-ordination	project design and co-ordination	Conceived and designed the experiments	Methodology|Project administration	YES
6270666	24979399	M.S.	7	radioligand binding assay, data analysis and manuscript preparation	radioligand binding assay, data analysis and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6270666	24979399	N.A.R.	7	project design and co-ordination	project design and co-ordination	Conceived and designed the experiments	Methodology|Project administration	YES
6270666	24979399	S.P.C.	7	molecular modelling. M.J.C.B: project design and co-ordination and manuscript preparation	molecular modelling. M.J.C.B: project design and co-ordination and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Project administration|Writing - Original Draft	YES
6270666	24979399	S.W.D.	7	project design and co-ordination	project design and co-ordination	Conceived and designed the experiments	Methodology|Project administration	YES
5731493	29244005	AGL	2	developed the algorithms|implemented the software|analyzed experimental results|wrote the manuscript	developed the algorithms	Contributed reagents/materials/analysis tools	Software	YES
5731493	29244005	AGL	2	developed the algorithms|implemented the software|analyzed experimental results|wrote the manuscript	implemented the software	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5731493	29244005	AGL	2	developed the algorithms|implemented the software|analyzed experimental results|wrote the manuscript	analyzed experimental results	Analyzed the data	Formal analysis	YES
5731493	29244005	AGL	2	developed the algorithms|implemented the software|analyzed experimental results|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5731493	29244005	AS	2	analyzed experimental results	analyzed experimental results	Analyzed the data	Formal analysis	YES
5731493	29244005	All authors	2	evaluated the final draft	evaluated the final draft	Wrote the paper	Writing - Original Draft	YES
5731493	29244005	CL	2	provided computational support	provided computational support	-	Formal analysis	YES
5731493	29244005	DSC	2	designed the study|developed the algorithms|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5731493	29244005	DSC	2	designed the study|developed the algorithms|wrote the manuscript	developed the algorithms	Contributed reagents/materials/analysis tools	Software	YES
5731493	29244005	DSC	2	designed the study|developed the algorithms|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5731493	29244005	HT	2	performed laboratory experiments	performed laboratory experiments	Performed the experiments	Investigation	YES
5731493	29244005	IR	2	developed the algorithms|implemented the software	developed the algorithms	Contributed reagents/materials/analysis tools	Software	YES
5731493	29244005	IR	2	developed the algorithms|implemented the software	implemented the software	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5731493	29244005	LGR	2	performed laboratory experiments	performed laboratory experiments	Performed the experiments	Investigation	YES
5731493	29244005	LP	2	performed laboratory experiments	performed laboratory experiments	Performed the experiments	Investigation	YES
5731493	29244005	MMe	2	performed laboratory experiments	performed laboratory experiments	Performed the experiments	Investigation	YES
5731493	29244005	MMi	2	implemented the software	implemented the software	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5731493	29244005	PS	2	developed the algorithms	developed the algorithms	Contributed reagents/materials/analysis tools	Software	YES
5731493	29244005	RT	2	coordinated the project	coordinated the project	-	Project administration	YES
5731493	29244005	SR	2	performed laboratory experiments	performed laboratory experiments	Performed the experiments	Investigation	YES
5731493	29244005	SS	2	developed the algorithms|implemented the software	developed the algorithms	Contributed reagents/materials/analysis tools	Software	YES
5731493	29244005	SS	2	developed the algorithms|implemented the software	implemented the software	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5731493	29244005	SW	2	implemented the software	implemented the software	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5731493	29244005	TS	2	coordinated the project	coordinated the project	-	Project administration	YES
5731493	29244005	VB	2	provided computational support	provided computational support	-	Formal analysis	YES
5731493	29244005	YK	2	designed the study|coordinated the project|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5731493	29244005	YK	2	designed the study|coordinated the project|wrote the manuscript	coordinated the project	-	Project administration	YES
5731493	29244005	YK	2	designed the study|coordinated the project|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5731493	29244005	YL	2	performed laboratory experiments	performed laboratory experiments	Performed the experiments	Investigation	YES
5731493	29244005	ZD	2	developed the algorithms|analyzed experimental results	developed the algorithms	Contributed reagents/materials/analysis tools	Software	YES
5731493	29244005	ZD	2	developed the algorithms|analyzed experimental results	analyzed experimental results	Analyzed the data	Formal analysis	YES
6264031	30486851	ADF	2	dietician, data analysis, interpretation, manuscript review	dietician, data analysis, interpretation, manuscript review	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
6264031	30486851	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6264031	30486851	JMS	2	corresponding author, funding, study design, oversight of project, data collection, analysis, interpretation, manuscript review	corresponding author, funding, study design, oversight of project, data collection, analysis, interpretation, manuscript review	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Funding acquisition|Investigation|Methodology|Supervision|Writing - Review & Editing	YES
6264031	30486851	JSM	2	primary author, study design, data collection, analysis and interpretation	primary author, study design, data collection, analysis and interpretation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
6264031	30486851	KCY	2	study design, data analysis, interpretation, manuscript review	study design, data analysis, interpretation, manuscript review	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
6264031	30486851	KDM	2	data collection, analysis, manuscript review	data collection, analysis, manuscript review	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
6264031	30486851	MDR	2	study design, data collection, analysis, interpretation, manuscript review	study design, data collection, analysis, interpretation, manuscript review	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Review & Editing	YES
6264031	30486851	RLO	2	data collection, analysis, manuscript review	data collection, analysis, manuscript review	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
5503848	28697583	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5503848	28697583	CLL	PLoS52	revised the paper	revised the paper	Wrote the paper	Writing - Review & Editing	YES
5503848	28697583	FZ	PLoS52	designed the experiment|wrote the paper	designed the experiment	Conceived and designed the experiments	Methodology	YES
5503848	28697583	FZ	PLoS52	designed the experiment|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5503848	28697583	WQW	PLoS52	designed the experiment|did the experiment and analysed the results	designed the experiment	Conceived and designed the experiments	Methodology	YES
5503848	28697583	WQW	PLoS52	designed the experiment|did the experiment and analysed the results	did the experiment and analysed the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5503848	28697583	XPW	PLoS52	revised the paper	revised the paper	Wrote the paper	Writing - Review & Editing	YES
5503848	28697583	YZ	PLoS52	designed the experiment|did the experiment and analysed the results|wrote the paper	designed the experiment	Conceived and designed the experiments	Methodology	YES
5503848	28697583	YZ	PLoS52	designed the experiment|did the experiment and analysed the results|wrote the paper	did the experiment and analysed the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5503848	28697583	YZ	PLoS52	designed the experiment|did the experiment and analysed the results|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5813261	29378775	DK	2	contributed to experiments	contributed to experiments	Performed the experiments	Investigation	YES
5813261	29378775	EF	2	designed experiments to identify e3 ligases	designed experiments to identify e3 ligases	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5813261	29378775	FL	2	designed experiments to identify e3 ligases	designed experiments to identify e3 ligases	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5813261	29378775	JCC	2	designed experiments to identify e3 ligases	designed experiments to identify e3 ligases	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5813261	29378775	KG	2	designed, performed, and analyzed experiments and wrote the manuscript	designed, performed, and analyzed experiments and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5813261	29378775	MB	2	designed experiments and wrote the manuscript	designed experiments and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5813261	29378775	MU	2	contributed to experiments	contributed to experiments	Performed the experiments	Investigation	YES
5813261	29378775	OV	2	contributed to experiments	contributed to experiments	Performed the experiments	Investigation	YES
5813261	29378775	all authors	2	contributed to edit the manuscript	contributed to edit the manuscript	Wrote the paper	Writing - Review & Editing	YES
4416753	25933119	ATH	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416753	25933119	ATH	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416753	25933119	GK	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4416753	25933119	GK	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416753	25933119	LD	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416753	25933119	MGK	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416753	25933119	MGL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416753	25933119	QL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416753	25933119	QL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416753	25933119	QL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416753	25933119	WL	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416753	25933119	YL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416753	25933119	YL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416753	25933119	YL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416753	25933119	YL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6267781	30497484	All authors	2	contributed to the study design and data interpretation|provided edits and final approval of the manuscript	contributed to the study design and data interpretation	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Methodology|Resources	YES
6267781	30497484	All authors	2	contributed to the study design and data interpretation|provided edits and final approval of the manuscript	provided edits and final approval of the manuscript	Wrote the paper	Writing - Review & Editing	YES
6267781	30497484	BTG	2	undertook management of the study, including study execution, overseeing data collection, management, quality assurance and analyses|were responsible for preparing the initial draft of the manuscript	undertook management of the study, including study execution, overseeing data collection, management, quality assurance and analyses	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation|Project administration|Supervision|Validation	YES
6267781	30497484	BTG	2	undertook management of the study, including study execution, overseeing data collection, management, quality assurance and analyses|were responsible for preparing the initial draft of the manuscript	were responsible for preparing the initial draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
6267781	30497484	CAS	2	undertook management of the study, including study execution, overseeing data collection, management, quality assurance and analyses	undertook management of the study, including study execution, overseeing data collection, management, quality assurance and analyses	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation|Project administration|Supervision|Validation	YES
6267781	30497484	CMK	2	designed the study|performed the statistical analysis and interpreted the findings|were responsible for preparing the initial draft of the manuscript|is the corresponding author for this paper	designed the study	Conceived and designed the experiments	Methodology	YES
6267781	30497484	CMK	2	designed the study|performed the statistical analysis and interpreted the findings|were responsible for preparing the initial draft of the manuscript|is the corresponding author for this paper	performed the statistical analysis and interpreted the findings	Analyzed the data	Formal analysis	YES
6267781	30497484	CMK	2	designed the study|performed the statistical analysis and interpreted the findings|were responsible for preparing the initial draft of the manuscript|is the corresponding author for this paper	were responsible for preparing the initial draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
6267781	30497484	CMK	2	designed the study|performed the statistical analysis and interpreted the findings|were responsible for preparing the initial draft of the manuscript|is the corresponding author for this paper	is the corresponding author for this paper	-	-	NO
6267781	30497484	KEW	2	undertook management of the study, including study execution, overseeing data collection, management, quality assurance and analyses	undertook management of the study, including study execution, overseeing data collection, management, quality assurance and analyses	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation|Project administration|Supervision|Validation	YES
6267781	30497484	PSH	2	performed the statistical analysis and interpreted the findings|were responsible for preparing the initial draft of the manuscript	performed the statistical analysis and interpreted the findings	Analyzed the data	Formal analysis	YES
6267781	30497484	PSH	2	performed the statistical analysis and interpreted the findings|were responsible for preparing the initial draft of the manuscript	were responsible for preparing the initial draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
6267781	30497484	RAS	2	undertook management of the study, including study execution, overseeing data collection, management, quality assurance and analyses|were responsible for preparing the initial draft of the manuscript	undertook management of the study, including study execution, overseeing data collection, management, quality assurance and analyses	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation|Project administration|Supervision|Validation	YES
6267781	30497484	RAS	2	undertook management of the study, including study execution, overseeing data collection, management, quality assurance and analyses|were responsible for preparing the initial draft of the manuscript	were responsible for preparing the initial draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
6267781	30497484	RW	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
1952173	17786221	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1952173	17786221	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1952173	17786221	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1952173	17786221	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1952173	17786221	MF	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1952173	17786221	MF	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1952173	17786221	MF	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5797612	29441086	JF-N	7	Acquired spectral measurements, prepared some figures and built the maps|Analyzed the data and built the models	Acquired spectral measurements, prepared some figures and built the maps	Performed the experiments	Investigation|Visualization	YES
5797612	29441086	JF-N	7	Acquired spectral measurements, prepared some figures and built the maps|Analyzed the data and built the models	Analyzed the data and built the models	Performed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5797612	29441086	JT	7	Designed the experimental layout, helped during field measurements and wrote the manuscript	Designed the experimental layout, helped during field measurements and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5797612	29441086	MD	7	Designed the experimental layout, helped during field measurements and wrote the manuscript	Designed the experimental layout, helped during field measurements and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5797612	29441086	MM	7	Analyzed the data and built the models	Analyzed the data and built the models	Performed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5797612	29441086	SG	7	Acquired spectral measurements, prepared some figures and built the maps|Created the algorithm for spectral assignment	Acquired spectral measurements, prepared some figures and built the maps	Performed the experiments	Investigation|Visualization	YES
5797612	29441086	SG	7	Acquired spectral measurements, prepared some figures and built the maps|Created the algorithm for spectral assignment	Created the algorithm for spectral assignment	Contributed reagents/materials/analysis tools	Software	YES
6270667	24959681	Gu-Ping Hu	2	mainly took part in the data test and biological activity assay	mainly took part in the data test and biological activity assay	Performed the experiments	Investigation	YES
6270667	24959681	Jun Wang	2	took charge of the throughout the research and writing	took charge of the throughout the research and writing	Wrote the paper	-	YES
6270667	24959681	Lan Liu	2	mainly took part in the structural elucidation	mainly took part in the structural elucidation	-	-	NO
6270667	24959681	Ming Kuang	2	mainly took part in the computational analyses	mainly took part in the computational analyses	Analyzed the data	Formal analysis	YES
6270667	24959681	Rui-Bo Wu	2	mainly took part in the computational analyses	mainly took part in the computational analyses	Analyzed the data	Formal analysis	YES
6270667	24959681	Yong-Cheng Lin	2	mainly checked the error about structures elucidation and writing	mainly checked the error about structures elucidation and writing	Wrote the paper	-	YES
6270667	24959681	Yu Lu	2	mainly took part in the extraction and isolation	mainly took part in the extraction and isolation	Performed the experiments	Investigation	YES
5731494	29244001	All authors	PLoS52	evaluated the final draft	evaluated the final draft	Wrote the paper	Writing - Original Draft	YES
5731494	29244001	DSC	PLoS52	designed the study|analysed the data|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5731494	29244001	DSC	PLoS52	designed the study|analysed the data|wrote the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
5731494	29244001	DSC	PLoS52	designed the study|analysed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5731494	29244001	JZ	PLoS52	analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
5731494	29244001	SR	PLoS52	conducted the laboratory experiments	conducted the laboratory experiments	Performed the experiments	Investigation	YES
5731494	29244001	YK	PLoS52	designed the study|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5731494	29244001	YK	PLoS52	designed the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5503849	28697586	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5503849	28697586	JHW	2	designed the study and performed the statistical analysis	designed the study and performed the statistical analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5503849	28697586	MHY	2	designed the study and performed the statistical analysis	designed the study and performed the statistical analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5503849	28697586	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5503849	28697586	WJK	2	carried out the experimental studies and wrote the main manuscript text	carried out the experimental studies and wrote the main manuscript text	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5503849	28697586	XSZ	2	carried out the experimental studies and wrote the main manuscript text	carried out the experimental studies and wrote the main manuscript text	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5503849	28697586	YKZ	2	carried out the experimental studies and wrote the main manuscript text	carried out the experimental studies and wrote the main manuscript text	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4416754	25932641	CMC	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416754	25932641	CMC	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416754	25932641	HWC	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416754	25932641	KHC	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416754	25932641	STC	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416754	25932641	WMH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416754	25932641	WMH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416754	25932641	WMH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416754	25932641	YCC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416754	25932641	YCC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416754	25932641	YCC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416754	25932641	YCC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416754	25932641	YCC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416754	25932641	YSL	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416754	25932641	YSL	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4685579	26598723	B.G.	2	designed the experiments, analysed the results and wrote the manuscript together|characterized the gene datasets for neurogenesis and neurotransmission	designed the experiments, analysed the results and wrote the manuscript together	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4685579	26598723	B.G.	2	designed the experiments, analysed the results and wrote the manuscript together|characterized the gene datasets for neurogenesis and neurotransmission	characterized the gene datasets for neurogenesis and neurotransmission	Performed the experiments	Investigation	YES
4685579	26598723	IFs	2	flow cytometry cell sorting for cell-type rnas, prepared corresponding rnas for drug/heat-shock and cell-type transcriptomics	flow cytometry cell sorting for cell-type rnas, prepared corresponding rnas for drug/heat-shock and cell-type transcriptomics	Performed the experiments	Investigation	YES
4685579	26598723	W.B.	2	designed the experiments, analysed the results and wrote the manuscript together	designed the experiments, analysed the results and wrote the manuscript together	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4685579	26598723	Y.W.	2	designed the experiments, analysed the results and wrote the manuscript together|characterized the gene datasets for neurogenesis and neurotransmission|dissected animals and prepared rnas for body column transcriptomics	designed the experiments, analysed the results and wrote the manuscript together	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4685579	26598723	Y.W.	2	designed the experiments, analysed the results and wrote the manuscript together|characterized the gene datasets for neurogenesis and neurotransmission|dissected animals and prepared rnas for body column transcriptomics	characterized the gene datasets for neurogenesis and neurotransmission	Performed the experiments	Investigation	YES
4685579	26598723	Y.W.	2	designed the experiments, analysed the results and wrote the manuscript together|characterized the gene datasets for neurogenesis and neurotransmission|dissected animals and prepared rnas for body column transcriptomics	dissected animals and prepared rnas for body column transcriptomics	Performed the experiments	Investigation	YES
4685579	26598723	YW	2	produced the assembly and the quantification of all rna seq transcriptomes, and designed primers for the cloning and the analysis of the expression of genes of interest	produced the assembly and the quantification of all rna seq transcriptomes, and designed primers for the cloning and the analysis of the expression of genes of interest	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5830915	29378774	CU	2	performed microbiota analyses and advised on microbiota-related experiments	performed microbiota analyses and advised on microbiota-related experiments	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5830915	29378774	DD-W	2	assisted with iga analyses	assisted with iga analyses	Analyzed the data	Formal analysis	YES
5830915	29378774	DK	2	assisted with iga analyses	assisted with iga analyses	Analyzed the data	Formal analysis	YES
5830915	29378774	JSdG	2	designed and performed research, analysed the data and wrote the manuscript	designed and performed research, analysed the data and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5830915	29378774	MG	2	contributed to the generation of conditional cd1d-deficient mice	contributed to the generation of conditional cd1d-deficient mice	-	-	NO
5830915	29378774	MJG	2	performed microbiota analyses and advised on microbiota-related experiments	performed microbiota analyses and advised on microbiota-related experiments	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5830915	29378774	PB	2	supervised and designed research, analysed the data and wrote the manuscript	supervised and designed research, analysed the data and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Supervision|Writing - Original Draft	YES
5830915	29378774	RJ	2	designed and performed research and analysed the data	designed and performed research and analysed the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
1952174	17786200	JP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1952174	17786200	JP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1952174	17786200	JP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1952174	17786200	MB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1952174	17786200	PL	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1952174	17786200	PL	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1952174	17786200	SE	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1952174	17786200	VM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1952174	17786200	VM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1952174	17786200	VM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6288941	30526607	E. Ivankova	2	performed the statistical analysis, providing language help and helped to draft the manuscript	performed the statistical analysis, providing language help and helped to draft the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6288941	30526607	R. Boyko	2	conceived of the study, and participated in its design and coordination	conceived of the study, and participated in its design and coordination	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
5731495	29244008	AMT	2	designed the computational work|designed the molecular experiments	designed the computational work	Conceived and designed the experiments	Formal analysis	YES
5731495	29244008	AMT	2	designed the computational work|designed the molecular experiments	designed the molecular experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5731495	29244008	JJP	2	designed the molecular experiments|performed the molecular experiments	designed the molecular experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5731495	29244008	JJP	2	designed the molecular experiments|performed the molecular experiments	performed the molecular experiments	Performed the experiments	Investigation	YES
5731495	29244008	S-HS	2	designed the computational work	designed the computational work	Conceived and designed the experiments	Formal analysis	YES
6270668	24796390	All authors	2	have contributed to, seen and approved the manuscript	have contributed to, seen and approved the manuscript	-	-	NO
6270668	24796390	Chonglin Cai	2	designed methods and experiments, carried out the laboratory experiments, analyzed the data, interpreted the results and wrote the paper	designed methods and experiments, carried out the laboratory experiments, analyzed the data, interpreted the results and wrote the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
6270668	24796390	Guangyou Chen	2	defined the research theme|designed methods and experiments, carried out the laboratory experiments, analyzed the data, interpreted the results and wrote the paper	defined the research theme	-	-	NO
6270668	24796390	Guangyou Chen	2	defined the research theme|designed methods and experiments, carried out the laboratory experiments, analyzed the data, interpreted the results and wrote the paper	designed methods and experiments, carried out the laboratory experiments, analyzed the data, interpreted the results and wrote the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
6270668	24796390	Jia Lu	2	co-designed the synthesis experiments, and co-worked on associated data collection and their interpretation	co-designed the synthesis experiments, and co-worked on associated data collection and their interpretation	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
6270668	24796390	Xing Zhang	2	defined the research theme	defined the research theme	-	-	NO
6270668	24796390	Yiwan Zhou	2	co-designed the synthesis experiments, and co-worked on associated data collection and their interpretation	co-designed the synthesis experiments, and co-worked on associated data collection and their interpretation	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5797619	29441081	BK	2	designed the study|wrote and edited the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5797619	29441081	BK	2	designed the study|wrote and edited the manuscript	wrote and edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5797619	29441081	CP	2	designed the study|performed experiments|provided analysis tools|performed analyses|wrote and edited the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5797619	29441081	CP	2	designed the study|performed experiments|provided analysis tools|performed analyses|wrote and edited the manuscript	performed experiments	Performed the experiments	Investigation	YES
5797619	29441081	CP	2	designed the study|performed experiments|provided analysis tools|performed analyses|wrote and edited the manuscript	provided analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5797619	29441081	CP	2	designed the study|performed experiments|provided analysis tools|performed analyses|wrote and edited the manuscript	performed analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5797619	29441081	CP	2	designed the study|performed experiments|provided analysis tools|performed analyses|wrote and edited the manuscript	wrote and edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5797619	29441081	FM	2	performed experiments|provided analysis tools|performed analyses	performed experiments	Performed the experiments	Investigation	YES
5797619	29441081	FM	2	performed experiments|provided analysis tools|performed analyses	provided analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5797619	29441081	FM	2	performed experiments|provided analysis tools|performed analyses	performed analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5797619	29441081	MM	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5797619	29441081	MR	2	provided analysis tools	provided analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5797619	29441081	SB	2	designed the study|performed experiments|wrote and edited the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5797619	29441081	SB	2	designed the study|performed experiments|wrote and edited the manuscript	performed experiments	Performed the experiments	Investigation	YES
5797619	29441081	SB	2	designed the study|performed experiments|wrote and edited the manuscript	wrote and edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5797619	29441081	TW	2	provided analysis tools	provided analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5503854	28697584	All	2	persons and organizations that have contributed to the work presented in this article are authors and mentioned as such	persons and organizations that have contributed to the work presented in this article are authors and mentioned as such	-	-	NO
5503854	28697584	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5503854	28697584	CM	2	designed the project as well as the experiments and interpreted the results|performed experiments|wrote the manuscript	designed the project as well as the experiments and interpreted the results	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5503854	28697584	CM	2	designed the project as well as the experiments and interpreted the results|performed experiments|wrote the manuscript	performed experiments	Performed the experiments	Investigation	YES
5503854	28697584	CM	2	designed the project as well as the experiments and interpreted the results|performed experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5503854	28697584	CS	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5503854	28697584	FM	2	designed the project as well as the experiments and interpreted the results|wrote the manuscript	designed the project as well as the experiments and interpreted the results	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5503854	28697584	FM	2	designed the project as well as the experiments and interpreted the results|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5503854	28697584	MB	2	designed the project as well as the experiments and interpreted the results|performed experiments	designed the project as well as the experiments and interpreted the results	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5503854	28697584	MB	2	designed the project as well as the experiments and interpreted the results|performed experiments	performed experiments	Performed the experiments	Investigation	YES
5503854	28697584	SV	2	performed the bioinformatic work	performed the bioinformatic work	Performed the experiments	Formal analysis|Investigation	YES
5503854	28697584	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
4629001	26558284	Bin Meng	2	contributed equally	contributed equally	-	-	NO
4629001	26558284	Weina Gao	2	contributed equally	contributed equally	-	-	NO
4416755	25933421	BKS	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416755	25933421	BKS	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416755	25933421	BKS	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416755	25933421	PDL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416755	25933421	PDL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416755	25933421	PDL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416755	25933421	PDL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416755	25933421	PYR	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416755	25933421	PYR	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416755	25933421	PYR	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1952175	17786222	CF	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1952175	17786222	IL	PLoS5	Performed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1952175	17786222	IL	PLoS5	Performed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1952175	17786222	KS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1952175	17786222	MF	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1952175	17786222	PL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1952175	17786222	RP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4685580	26598724	A.B.K.	2	analysed molecular data and wrote corresponding sections of the paper|constructed phylogenetic trees	analysed molecular data and wrote corresponding sections of the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4685580	26598724	A.B.K.	2	analysed molecular data and wrote corresponding sections of the paper|constructed phylogenetic trees	constructed phylogenetic trees	Performed the experiments	Investigation	YES
4685580	26598724	L.L.M.	2	designed the study and wrote the final paper|analysed molecular data and wrote corresponding sections of the paper	designed the study and wrote the final paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4685580	26598724	L.L.M.	2	designed the study and wrote the final paper|analysed molecular data and wrote corresponding sections of the paper	analysed molecular data and wrote corresponding sections of the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5830917	29343546	AD	2	designed and performed the experiments and interpreted the results	designed and performed the experiments and interpreted the results	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5830917	29343546	AKT	2	designed and performed the experiments and interpreted the results	designed and performed the experiments and interpreted the results	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5830917	29343546	AS	2	designed and performed the experiments and interpreted the results	designed and performed the experiments and interpreted the results	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5830917	29343546	CS	2	supervised the study, designed the experiments, and interpreted the results	supervised the study, designed the experiments, and interpreted the results	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology|Supervision	YES
5830917	29343546	GZ	2	designed and performed the experiments and interpreted the results|wrote the manuscript and drafted the figures	designed and performed the experiments and interpreted the results	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5830917	29343546	GZ	2	designed and performed the experiments and interpreted the results|wrote the manuscript and drafted the figures	wrote the manuscript and drafted the figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5830917	29343546	JR	2	designed and performed the experiments and interpreted the results	designed and performed the experiments and interpreted the results	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5830917	29343546	ME	2	designed and performed the experiments and interpreted the results	designed and performed the experiments and interpreted the results	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5830917	29343546	MS	2	designed and performed the experiments and interpreted the results	designed and performed the experiments and interpreted the results	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5830917	29343546	RT	2	designed and performed the experiments and interpreted the results	designed and performed the experiments and interpreted the results	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5830917	29343546	SM	2	supervised the study, designed the experiments, and interpreted the results|wrote the manuscript and drafted the figures	supervised the study, designed the experiments, and interpreted the results	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology|Supervision	YES
5830917	29343546	SM	2	supervised the study, designed the experiments, and interpreted the results|wrote the manuscript and drafted the figures	wrote the manuscript and drafted the figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5830917	29343546	ST	2	designed and performed the experiments and interpreted the results	designed and performed the experiments and interpreted the results	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5830917	29343546	TP	2	wrote the macro for data analysis	wrote the macro for data analysis	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6291964	30541572	ACT	4	The present study was designed by|data were collected by	The present study was designed by	Conceived and designed the experiments	Methodology	YES
6291964	30541572	ACT	4	The present study was designed by|data were collected by	data were collected by	Performed the experiments	Investigation	YES
6291964	30541572	BAF	4	The present study was designed by|data interpretation and manuscript preparation were undertaken by	The present study was designed by	Conceived and designed the experiments	Methodology	YES
6291964	30541572	BAF	4	The present study was designed by|data interpretation and manuscript preparation were undertaken by	data interpretation and manuscript preparation were undertaken by	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6291964	30541572	BJL	4	The present study was designed by|data interpretation and manuscript preparation were undertaken by	The present study was designed by	Conceived and designed the experiments	Methodology	YES
6291964	30541572	BJL	4	The present study was designed by|data interpretation and manuscript preparation were undertaken by	data interpretation and manuscript preparation were undertaken by	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6291964	30541572	CAS	4	data were collected by	data were collected by	Performed the experiments	Investigation	YES
6291964	30541572	JAL	4	The present study was designed by|data interpretation and manuscript preparation were undertaken by	The present study was designed by	Conceived and designed the experiments	Methodology	YES
6291964	30541572	JAL	4	The present study was designed by|data interpretation and manuscript preparation were undertaken by	data interpretation and manuscript preparation were undertaken by	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6291964	30541572	JMJ	4	data were collected by	data were collected by	Performed the experiments	Investigation	YES
6291964	30541572	JRM	4	The present study was designed by|data interpretation and manuscript preparation were undertaken by	The present study was designed by	Conceived and designed the experiments	Methodology	YES
6291964	30541572	JRM	4	The present study was designed by|data interpretation and manuscript preparation were undertaken by	data interpretation and manuscript preparation were undertaken by	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6291964	30541572	KAH	4	The present study was designed by|data interpretation and manuscript preparation were undertaken by	The present study was designed by	Conceived and designed the experiments	Methodology	YES
6291964	30541572	KAH	4	The present study was designed by|data interpretation and manuscript preparation were undertaken by	data interpretation and manuscript preparation were undertaken by	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6291964	30541572	KMN	4	The present study was designed by|data interpretation and manuscript preparation were undertaken by	The present study was designed by	Conceived and designed the experiments	Methodology	YES
6291964	30541572	KMN	4	The present study was designed by|data interpretation and manuscript preparation were undertaken by	data interpretation and manuscript preparation were undertaken by	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6291964	30541572	MMH	4	data were collected by	data were collected by	Performed the experiments	Investigation	YES
6291964	30541572	PHF	4	The present study was designed by|data were collected by|data interpretation and manuscript preparation were undertaken by	The present study was designed by	Conceived and designed the experiments	Methodology	YES
6291964	30541572	PHF	4	The present study was designed by|data were collected by|data interpretation and manuscript preparation were undertaken by	data were collected by	Performed the experiments	Investigation	YES
6291964	30541572	PHF	4	The present study was designed by|data were collected by|data interpretation and manuscript preparation were undertaken by	data interpretation and manuscript preparation were undertaken by	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6291964	30541572	RMV	4	data were collected by	data were collected by	Performed the experiments	Investigation	YES
5731501	29244006	BJH	2	provided test data, analyzed results, and reviewed the manuscript	provided test data, analyzed results, and reviewed the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
5731501	29244006	ECR	2	developed the overall project goals|supervised the overall project, provided the necessary lab space and computational resources for project completion, and led development of the manuscript	developed the overall project goals	-	-	NO
5731501	29244006	ECR	2	developed the overall project goals|supervised the overall project, provided the necessary lab space and computational resources for project completion, and led development of the manuscript	supervised the overall project, provided the necessary lab space and computational resources for project completion, and led development of the manuscript	Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Supervision|Writing - Original Draft	YES
5731501	29244006	ES	2	was responsible for code preparation, development of the project, and manuscript preparation	was responsible for code preparation, development of the project, and manuscript preparation	Wrote the paper	Writing - Original Draft	YES
5731501	29244006	JCP	2	developed the overall project goals|provided test data, analyzed results, and reviewed the manuscript	developed the overall project goals	-	-	NO
5731501	29244006	JCP	2	developed the overall project goals|provided test data, analyzed results, and reviewed the manuscript	provided test data, analyzed results, and reviewed the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
5731501	29244006	KW	2	performed testing of utr analysis of microarrays and reviewed the manuscript	performed testing of utr analysis of microarrays and reviewed the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5503855	28697585	AM	2	designed the study, participated in the experiment, analyzed the data, revised the manuscript	designed the study, participated in the experiment, analyzed the data, revised the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Review & Editing	YES
5503855	28697585	AU	2	isolated the microorganisms, performed the experiments, drafted the manuscript	isolated the microorganisms, performed the experiments, drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5503855	28697585	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5503855	28697585	LF	2	collected the soil samples and revised the manuscript	collected the soil samples and revised the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5503855	28697585	MS	2	collected the soil samples and revised the manuscript	collected the soil samples and revised the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5503855	28697585	WK	2	collected the soil samples and revised the manuscript	collected the soil samples and revised the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5503855	28697585	WR	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
1952176	17786206	HM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1952176	17786206	JS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1952176	17786206	LK	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1952176	17786206	LM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1952176	17786206	LM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1952176	17786206	LM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1952176	17786206	LM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1952176	17786206	MO	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5797622	29441079	All authors	2	read and approved the manuscript	read and approved the manuscript	-	-	NO
4416756	25932926	BM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416756	25932926	BM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416756	25932926	BM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416756	25932926	BM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416756	25932926	BM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416756	25932926	ERM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416756	25932926	ERM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416756	25932926	ERM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416756	25932926	ERM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416756	25932926	MF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416756	25932926	MF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416756	25932926	MF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416756	25932926	MF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416756	25932926	MF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416756	25932926	TVV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416756	25932926	TVV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416756	25932926	TVV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416756	25932926	TVV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416756	25932926	TVV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270670	25178061	All authors	2	have contributed equally to this work	have contributed equally to this work	-	-	NO
4685582	26598726	D.A.	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4685582	26598726	T.B.	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6299666	30563538	All authors	2	were involved in the study|reviewed the paper and approved the final version prior to submission	were involved in the study	-	-	NO
6299666	30563538	All authors	2	were involved in the study|reviewed the paper and approved the final version prior to submission	reviewed the paper and approved the final version prior to submission	Wrote the paper	Writing - Review & Editing	YES
6299666	30563538	J.R.	2	conceived and designed the study|constructed the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6299666	30563538	J.R.	2	conceived and designed the study|constructed the manuscript	constructed the manuscript	Performed the experiments	Investigation	YES
6299666	30563538	L.B.	2	conceived and designed the study|was centrally involved with data collection|constructed the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6299666	30563538	L.B.	2	conceived and designed the study|was centrally involved with data collection|constructed the manuscript	was centrally involved with data collection	Performed the experiments	Investigation	YES
6299666	30563538	L.B.	2	conceived and designed the study|was centrally involved with data collection|constructed the manuscript	constructed the manuscript	Performed the experiments	Investigation	YES
5830921	29438978	AEC	2	designed and conducted the gel filtration, protein expression and purification, and structural nmr experiments|developed the c-terminal mbp vector and phase separation assay|wrote the manuscript with input from the authors	designed and conducted the gel filtration, protein expression and purification, and structural nmr experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5830921	29438978	AEC	2	designed and conducted the gel filtration, protein expression and purification, and structural nmr experiments|developed the c-terminal mbp vector and phase separation assay|wrote the manuscript with input from the authors	developed the c-terminal mbp vector and phase separation assay	Performed the experiments	Investigation	YES
5830921	29438978	AEC	2	designed and conducted the gel filtration, protein expression and purification, and structural nmr experiments|developed the c-terminal mbp vector and phase separation assay|wrote the manuscript with input from the authors	wrote the manuscript with input from the authors	Wrote the paper	Writing - Original Draft	YES
5830921	29438978	AN	2	carried out and analyzed them	carried out and analyzed them	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5830921	29438978	ANR	2	carried them out	carried them out	Performed the experiments	Investigation	YES
5830921	29438978	AW	2	designed and conducted the gel filtration, protein expression and purification, and structural nmr experiments|wrote the manuscript with input from the authors	designed and conducted the gel filtration, protein expression and purification, and structural nmr experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5830921	29438978	AW	2	designed and conducted the gel filtration, protein expression and purification, and structural nmr experiments|wrote the manuscript with input from the authors	wrote the manuscript with input from the authors	Wrote the paper	Writing - Original Draft	YES
5830921	29438978	DRM	2	designed and conducted the gel filtration, protein expression and purification, and structural nmr experiments	designed and conducted the gel filtration, protein expression and purification, and structural nmr experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5830921	29438978	EWM	2	carried them out	carried them out	Performed the experiments	Investigation	YES
5830921	29438978	FS	2	conceived of, performed, and analyzed the immunoblotting experiments	conceived of, performed, and analyzed the immunoblotting experiments	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation	YES
5830921	29438978	MTN	2	designed and conducted the gel filtration, protein expression and purification, and structural nmr experiments	designed and conducted the gel filtration, protein expression and purification, and structural nmr experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5830921	29438978	NLF	2	designed and conducted the gel filtration, protein expression and purification, and structural nmr experiments|wrote the manuscript with input from the authors	designed and conducted the gel filtration, protein expression and purification, and structural nmr experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5830921	29438978	NLF	2	designed and conducted the gel filtration, protein expression and purification, and structural nmr experiments|wrote the manuscript with input from the authors	wrote the manuscript with input from the authors	Wrote the paper	Writing - Original Draft	YES
5830921	29438978	SNR	2	conceived of, performed, and analyzed the immunoblotting experiments	conceived of, performed, and analyzed the immunoblotting experiments	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation	YES
5830921	29438978	VHR	2	designed and conducted the gel filtration, protein expression and purification, and structural nmr experiments	designed and conducted the gel filtration, protein expression and purification, and structural nmr experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5731502	29244000	JL	2	conceived and designed experiments|implemented and conducted all bioinformatics analyses	conceived and designed experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5731502	29244000	JL	2	conceived and designed experiments|implemented and conducted all bioinformatics analyses	implemented and conducted all bioinformatics analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5731502	29244000	MT	2	implemented and conducted all bioinformatics analyses	implemented and conducted all bioinformatics analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5731502	29244000	YK	2	conceived and designed experiments	conceived and designed experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1952177	17786219	BZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1952177	17786219	BZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1952177	17786219	BZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1952177	17786219	BZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1952177	17786219	HB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1952177	17786219	HB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1952177	17786219	HB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1952177	17786219	HB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1952177	17786219	HB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416757	25933166	AMI	PLoS5	Edited manuscript	Edited manuscript	Wrote the paper	Writing - Review & Editing	YES
4416757	25933166	CUT	PLoS5	Analyzed the data|Edited manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4416757	25933166	CUT	PLoS5	Analyzed the data|Edited manuscript	Edited manuscript	Wrote the paper	Writing - Review & Editing	YES
4416757	25933166	DHC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Edited manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416757	25933166	DHC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Edited manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4416757	25933166	DHC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Edited manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416757	25933166	DHC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Edited manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416757	25933166	DHC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Edited manuscript	Edited manuscript	Wrote the paper	Writing - Review & Editing	YES
4416757	25933166	HBZ	PLoS5	Performed the experiments|Edited manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4416757	25933166	HBZ	PLoS5	Performed the experiments|Edited manuscript	Edited manuscript	Wrote the paper	Writing - Review & Editing	YES
4416757	25933166	LFC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Edited manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416757	25933166	LFC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Edited manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4416757	25933166	LFC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Edited manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4416757	25933166	LFC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Edited manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416757	25933166	LFC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Edited manuscript	Edited manuscript	Wrote the paper	Writing - Review & Editing	YES
4416757	25933166	MEES	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Edited manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416757	25933166	MEES	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Edited manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4416757	25933166	MEES	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Edited manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416757	25933166	MEES	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Edited manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416757	25933166	MEES	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Edited manuscript	Edited manuscript	Wrote the paper	Writing - Review & Editing	YES
4416757	25933166	RKM	PLoS5	Performed the experiments|Analyzed the data|Edited manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4416757	25933166	RKM	PLoS5	Performed the experiments|Analyzed the data|Edited manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4416757	25933166	RKM	PLoS5	Performed the experiments|Analyzed the data|Edited manuscript	Edited manuscript	Wrote the paper	Writing - Review & Editing	YES
6346288	30774885	All authors	2	have given approval to the final version of the manuscript	have given approval to the final version of the manuscript	-	-	NO
6270671	25379646	NS	4	SH wrote the first draft of this article that was then followed by modifications by	SH wrote the first draft of this article that was then followed by modifications by	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5514005	28724261	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5514005	28724261	CW	2	participated in the in vitro experiments	participated in the in vitro experiments	Performed the experiments	Investigation	YES
5514005	28724261	FC	2	participated in the animal experiments	participated in the animal experiments	Performed the experiments	Investigation	YES
5514005	28724261	GZ	2	participated in the animal experiments	participated in the animal experiments	Performed the experiments	Investigation	YES
5514005	28724261	JW	2	designed the research, analyzed data, and edited the manuscript	designed the research, analyzed data, and edited the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
5514005	28724261	MC	2	participated in the animal experiments	participated in the animal experiments	Performed the experiments	Investigation	YES
5514005	28724261	MS	2	participated in the in vitro experiments	participated in the in vitro experiments	Performed the experiments	Investigation	YES
5514005	28724261	SC	2	participated in the in vitro experiments	participated in the in vitro experiments	Performed the experiments	Investigation	YES
5514005	28724261	SW	2	designed and performed research, collected and analyzed data, and wrote the manuscript	designed and performed research, collected and analyzed data, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5514005	28724261	TC	2	contributed to designing the study	contributed to designing the study	Conceived and designed the experiments	Methodology	YES
5514005	28724261	XR	2	contributed to designing the study	contributed to designing the study	Conceived and designed the experiments	Methodology	YES
5514005	28724261	YS	2	designed and supervised the research	designed and supervised the research	Conceived and designed the experiments	Methodology|Supervision	YES
5514005	28724261	YX	2	designed the research, analyzed data, and edited the manuscript	designed the research, analyzed data, and edited the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
4685585	26598729	A.H.	2	edited the paper	edited the paper	Wrote the paper	Writing - Review & Editing	YES
4685585	26598729	All authors	2	discussed and commented on the data	discussed and commented on the data	-	-	NO
4685585	26598729	G.H.W.	2	conducted the experiments and drafted the manuscript	conducted the experiments and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4685585	26598729	J.M.M.D.	2	conducted the experiments and drafted the manuscript|did the collections of the specimens	conducted the experiments and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4685585	26598729	J.M.M.D.	2	conducted the experiments and drafted the manuscript|did the collections of the specimens	did the collections of the specimens	Performed the experiments	Investigation	YES
4685585	26598729	N.J.S.	2	edited the paper	edited the paper	Wrote the paper	Writing - Review & Editing	YES
5797632	29441074	AP	PLoS52	conceived the main concept of the study|designed the experiment and performed field data collection|analyzed the data|provided plant materials, instruments, and computing resources used in the study|contributed to writing the manuscript	conceived the main concept of the study	Conceived and designed the experiments	Conceptualization	YES
5797632	29441074	AP	PLoS52	conceived the main concept of the study|designed the experiment and performed field data collection|analyzed the data|provided plant materials, instruments, and computing resources used in the study|contributed to writing the manuscript	designed the experiment and performed field data collection	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5797632	29441074	AP	PLoS52	conceived the main concept of the study|designed the experiment and performed field data collection|analyzed the data|provided plant materials, instruments, and computing resources used in the study|contributed to writing the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5797632	29441074	AP	PLoS52	conceived the main concept of the study|designed the experiment and performed field data collection|analyzed the data|provided plant materials, instruments, and computing resources used in the study|contributed to writing the manuscript	provided plant materials, instruments, and computing resources used in the study	Performed the experiments|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5797632	29441074	AP	PLoS52	conceived the main concept of the study|designed the experiment and performed field data collection|analyzed the data|provided plant materials, instruments, and computing resources used in the study|contributed to writing the manuscript	contributed to writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5797632	29441074	All authors	PLoS52	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5797632	29441074	CL	PLoS52	conceived the main concept of the study|designed the experiment and performed field data collection|analyzed the data|provided plant materials, instruments, and computing resources used in the study|contributed to writing the manuscript	conceived the main concept of the study	Conceived and designed the experiments	Conceptualization	YES
5797632	29441074	CL	PLoS52	conceived the main concept of the study|designed the experiment and performed field data collection|analyzed the data|provided plant materials, instruments, and computing resources used in the study|contributed to writing the manuscript	designed the experiment and performed field data collection	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5797632	29441074	CL	PLoS52	conceived the main concept of the study|designed the experiment and performed field data collection|analyzed the data|provided plant materials, instruments, and computing resources used in the study|contributed to writing the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5797632	29441074	CL	PLoS52	conceived the main concept of the study|designed the experiment and performed field data collection|analyzed the data|provided plant materials, instruments, and computing resources used in the study|contributed to writing the manuscript	provided plant materials, instruments, and computing resources used in the study	Performed the experiments|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5797632	29441074	CL	PLoS52	conceived the main concept of the study|designed the experiment and performed field data collection|analyzed the data|provided plant materials, instruments, and computing resources used in the study|contributed to writing the manuscript	contributed to writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5797632	29441074	JR	PLoS52	designed the experiment and performed field data collection	designed the experiment and performed field data collection	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5797632	29441074	RX	PLoS52	designed the experiment and performed field data collection|analyzed the data	designed the experiment and performed field data collection	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5797632	29441074	RX	PLoS52	designed the experiment and performed field data collection|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5797632	29441074	SS	PLoS52	designed the experiment and performed field data collection|analyzed the data	designed the experiment and performed field data collection	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5797632	29441074	SS	PLoS52	designed the experiment and performed field data collection|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5797632	29441074	YJ	PLoS52	conceived the main concept of the study|designed the experiment and performed field data collection|developed the data processing pipeline|analyzed the data|contributed to writing the manuscript	conceived the main concept of the study	Conceived and designed the experiments	Conceptualization	YES
5797632	29441074	YJ	PLoS52	conceived the main concept of the study|designed the experiment and performed field data collection|developed the data processing pipeline|analyzed the data|contributed to writing the manuscript	designed the experiment and performed field data collection	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5797632	29441074	YJ	PLoS52	conceived the main concept of the study|designed the experiment and performed field data collection|developed the data processing pipeline|analyzed the data|contributed to writing the manuscript	developed the data processing pipeline	Analyzed the data	Data curation	YES
5797632	29441074	YJ	PLoS52	conceived the main concept of the study|designed the experiment and performed field data collection|developed the data processing pipeline|analyzed the data|contributed to writing the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5797632	29441074	YJ	PLoS52	conceived the main concept of the study|designed the experiment and performed field data collection|developed the data processing pipeline|analyzed the data|contributed to writing the manuscript	contributed to writing the manuscript	Wrote the paper	Writing - Original Draft	YES
4416758	25933372	MHD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416758	25933372	MHD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416758	25933372	MHD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416758	25933372	MHD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416758	25933372	SJM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416758	25933372	SJM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416758	25933372	SJM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416758	25933372	SJM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6310931	30594211	AJS-O	2	selected the articles included|analyzed the articles included and prepared figures and tables|revised the manuscript|approved the final version of the manuscript	selected the articles included	-	-	NO
6310931	30594211	AJS-O	2	selected the articles included|analyzed the articles included and prepared figures and tables|revised the manuscript|approved the final version of the manuscript	analyzed the articles included and prepared figures and tables	Analyzed the data	Formal analysis|Visualization	YES
6310931	30594211	AJS-O	2	selected the articles included|analyzed the articles included and prepared figures and tables|revised the manuscript|approved the final version of the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
6310931	30594211	AJS-O	2	selected the articles included|analyzed the articles included and prepared figures and tables|revised the manuscript|approved the final version of the manuscript	approved the final version of the manuscript	-	-	NO
6310931	30594211	FM	2	assessed the methodological quality of the studies|analyzed the articles included and prepared figures and tables|drafted the manuscript|approved the final version of the manuscript	assessed the methodological quality of the studies	Performed the experiments	Methodology|Validation	YES
6310931	30594211	FM	2	assessed the methodological quality of the studies|analyzed the articles included and prepared figures and tables|drafted the manuscript|approved the final version of the manuscript	analyzed the articles included and prepared figures and tables	Analyzed the data	Formal analysis|Visualization	YES
6310931	30594211	FM	2	assessed the methodological quality of the studies|analyzed the articles included and prepared figures and tables|drafted the manuscript|approved the final version of the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
6310931	30594211	FM	2	assessed the methodological quality of the studies|analyzed the articles included and prepared figures and tables|drafted the manuscript|approved the final version of the manuscript	approved the final version of the manuscript	-	-	NO
6310931	30594211	LML-G	2	conceived and designed the review|analyzed the articles included and prepared figures and tables|drafted the manuscript|approved the final version of the manuscript	conceived and designed the review	Conceived and designed the experiments	Conceptualization	YES
6310931	30594211	LML-G	2	conceived and designed the review|analyzed the articles included and prepared figures and tables|drafted the manuscript|approved the final version of the manuscript	analyzed the articles included and prepared figures and tables	Analyzed the data	Formal analysis|Visualization	YES
6310931	30594211	LML-G	2	conceived and designed the review|analyzed the articles included and prepared figures and tables|drafted the manuscript|approved the final version of the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
6310931	30594211	LML-G	2	conceived and designed the review|analyzed the articles included and prepared figures and tables|drafted the manuscript|approved the final version of the manuscript	approved the final version of the manuscript	-	-	NO
6310931	30594211	PJ	2	selected the articles included|assessed the methodological quality of the studies|drafted the manuscript|approved the final version of the manuscript	selected the articles included	-	-	NO
6310931	30594211	PJ	2	selected the articles included|assessed the methodological quality of the studies|drafted the manuscript|approved the final version of the manuscript	assessed the methodological quality of the studies	Performed the experiments	Methodology|Validation	YES
6310931	30594211	PJ	2	selected the articles included|assessed the methodological quality of the studies|drafted the manuscript|approved the final version of the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
6310931	30594211	PJ	2	selected the articles included|assessed the methodological quality of the studies|drafted the manuscript|approved the final version of the manuscript	approved the final version of the manuscript	-	-	NO
6310931	30594211	RD	2	conceived and designed the review|assessed the methodological quality of the studies|analyzed the articles included and prepared figures and tables|drafted the manuscript|revised the manuscript|approved the final version of the manuscript	conceived and designed the review	Conceived and designed the experiments	Conceptualization	YES
6310931	30594211	RD	2	conceived and designed the review|assessed the methodological quality of the studies|analyzed the articles included and prepared figures and tables|drafted the manuscript|revised the manuscript|approved the final version of the manuscript	assessed the methodological quality of the studies	Performed the experiments	Methodology|Validation	YES
6310931	30594211	RD	2	conceived and designed the review|assessed the methodological quality of the studies|analyzed the articles included and prepared figures and tables|drafted the manuscript|revised the manuscript|approved the final version of the manuscript	analyzed the articles included and prepared figures and tables	Analyzed the data	Formal analysis|Visualization	YES
6310931	30594211	RD	2	conceived and designed the review|assessed the methodological quality of the studies|analyzed the articles included and prepared figures and tables|drafted the manuscript|revised the manuscript|approved the final version of the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
6310931	30594211	RD	2	conceived and designed the review|assessed the methodological quality of the studies|analyzed the articles included and prepared figures and tables|drafted the manuscript|revised the manuscript|approved the final version of the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
6310931	30594211	RD	2	conceived and designed the review|assessed the methodological quality of the studies|analyzed the articles included and prepared figures and tables|drafted the manuscript|revised the manuscript|approved the final version of the manuscript	approved the final version of the manuscript	-	-	NO
5731601	29244002	All authors	2	contributed to the design of the approach, the analysis of the results, and the writing of the paper	contributed to the design of the approach, the analysis of the results, and the writing of the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5731601	29244002	CP	2	conceived the study|coordinated and supervised the work	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5731601	29244002	CP	2	conceived the study|coordinated and supervised the work	coordinated and supervised the work	-	Project administration|Supervision	YES
5731601	29244002	MC	2	conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5731601	29244002	SG	2	implemented the approach and performed the experiments	implemented the approach and performed the experiments	Performed the experiments	Investigation	YES
1955830	17848992	CK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1955830	17848992	CK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1955830	17848992	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1955830	17848992	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1955830	17848992	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1955830	17848992	RK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1955830	17848992	RK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1955830	17848992	ZM	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1955830	17848992	ZM	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5852645	29467217	AAJ	CRediT	Investigation|writing--review and editing|funding acquisition	Investigation	Performed the experiments	Investigation	YES
5852645	29467217	AAJ	CRediT	Investigation|writing--review and editing|funding acquisition	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
5852645	29467217	AAJ	CRediT	Investigation|writing--review and editing|funding acquisition	funding acquisition	-	Funding acquisition	YES
5852645	29467217	HK	CRediT	Investigation|funding acquisition	Investigation	Performed the experiments	Investigation	YES
5852645	29467217	HK	CRediT	Investigation|funding acquisition	funding acquisition	-	Funding acquisition	YES
5852645	29467217	JGR	CRediT	Investigation|writing--original draft|writing--review and editing	Investigation	Performed the experiments	Investigation	YES
5852645	29467217	JGR	CRediT	Investigation|writing--original draft|writing--review and editing	writing--original draft	Wrote the paper	Writing - Original Draft	YES
5852645	29467217	JGR	CRediT	Investigation|writing--original draft|writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
5852645	29467217	KS	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
5852645	29467217	MP	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
5852645	29467217	OM	CRediT	writing--review and editing	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
5852645	29467217	SO	CRediT	Investigation|funding acquisition	Investigation	Performed the experiments	Investigation	YES
5852645	29467217	SO	CRediT	Investigation|funding acquisition	funding acquisition	-	Funding acquisition	YES
5852645	29467217	WCE	CRediT	writing--original draft|writing--review and editing|supervision|funding acquisition	writing--original draft	Wrote the paper	Writing - Original Draft	YES
5852645	29467217	WCE	CRediT	writing--original draft|writing--review and editing|supervision|funding acquisition	writing--review and editing	Wrote the paper	Writing - Review & Editing	YES
5852645	29467217	WCE	CRediT	writing--original draft|writing--review and editing|supervision|funding acquisition	supervision	-	Supervision	YES
5852645	29467217	WCE	CRediT	writing--original draft|writing--review and editing|supervision|funding acquisition	funding acquisition	-	Funding acquisition	YES
6270672	24914893	Berit Smestad Paulsen	2	participated in desining the study	participated in desining the study	-	-	NO
6270672	24914893	Kari Tvete Inngjerdingen	2	participated in desining the study	participated in desining the study	-	-	NO
6270672	24914893	Yuan-Feng Zou	2	participated in desining the study	participated in desining the study	-	-	NO
4416759	25933205	CY	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416759	25933205	CY	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416759	25933205	FJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416759	25933205	FJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416759	25933205	FJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416759	25933205	FJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416759	25933205	FJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416759	25933205	JZ	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416759	25933205	JZ	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416759	25933205	LG	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416759	25933205	LG	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416759	25933205	SL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416759	25933205	SL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416759	25933205	SL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416759	25933205	SL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416759	25933205	SL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416759	25933205	YQ	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5514006	28724263	CZ	1	Design of the experiments|Data analyses|Graphics	Design of the experiments	Conceived and designed the experiments	Methodology	YES
5514006	28724263	CZ	1	Design of the experiments|Data analyses|Graphics	Data analyses	Analyzed the data	Formal analysis	YES
5514006	28724263	CZ	1	Design of the experiments|Data analyses|Graphics	Graphics	-	-	NO
5514006	28724263	DMG	1	Design of the experiments|Data analyses|Graphics	Design of the experiments	Conceived and designed the experiments	Methodology	YES
5514006	28724263	DMG	1	Design of the experiments|Data analyses|Graphics	Data analyses	Analyzed the data	Formal analysis	YES
5514006	28724263	DMG	1	Design of the experiments|Data analyses|Graphics	Graphics	-	-	NO
5514006	28724263	MMM	1	Data analyses|Graphics	Data analyses	Analyzed the data	Formal analysis	YES
5514006	28724263	MMM	1	Data analyses|Graphics	Graphics	-	-	NO
5514006	28724263	RBZ	1	Design of the experiments|Data analyses|Graphics	Design of the experiments	Conceived and designed the experiments	Methodology	YES
5514006	28724263	RBZ	1	Design of the experiments|Data analyses|Graphics	Data analyses	Analyzed the data	Formal analysis	YES
5514006	28724263	RBZ	1	Design of the experiments|Data analyses|Graphics	Graphics	-	-	NO
5514006	28724263	ZLZ	1	Design of the experiments|Data analyses	Design of the experiments	Conceived and designed the experiments	Methodology	YES
5514006	28724263	ZLZ	1	Design of the experiments|Data analyses	Data analyses	Analyzed the data	Formal analysis	YES
5731603	29244003	DC	2	supervised this project and edited the manuscript	supervised this project and edited the manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
5731603	29244003	SJE	2	provided the experimental data|supervised this project and edited the manuscript	provided the experimental data	Contributed reagents/materials/analysis tools	Resources	YES
5731603	29244003	SJE	2	provided the experimental data|supervised this project and edited the manuscript	supervised this project and edited the manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
5731603	29244003	SZ	2	implemented the program, designed and performed experiments, analyzed the data, and prepared the manuscript	implemented the program, designed and performed experiments, analyzed the data, and prepared the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5797636	29441082	DC	2	designed the experiments and finished the manuscript	designed the experiments and finished the manuscript	Conceived and designed the experiments	Methodology	YES
5797636	29441082	MZ	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5797636	29441082	QR	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5797636	29441082	XZ	2	provided guidance and support	provided guidance and support	-	Supervision	YES
5797636	29441082	YC	2	designed the experiments and finished the manuscript|provided guidance and support	designed the experiments and finished the manuscript	Conceived and designed the experiments	Methodology	YES
5797636	29441082	YC	2	designed the experiments and finished the manuscript|provided guidance and support	provided guidance and support	-	Supervision	YES
5797636	29441082	YL	2	provided guidance and support	provided guidance and support	-	Supervision	YES
5797636	29441082	ZC	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5852646	29335281	ALM	2	designed and carried out experiments	designed and carried out experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5852646	29335281	CG	2	designed and carried out experiments	designed and carried out experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5852646	29335281	CJS	2	designed and carried out informatic analyses|wrote the manuscript	designed and carried out informatic analyses	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5852646	29335281	CJS	2	designed and carried out informatic analyses|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5852646	29335281	DMS	2	assisted with the experiments	assisted with the experiments	Performed the experiments	Investigation	YES
5852646	29335281	JLR	2	conceived the project|wrote the manuscript|supervised and funded the project	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5852646	29335281	JLR	2	conceived the project|wrote the manuscript|supervised and funded the project	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5852646	29335281	JLR	2	conceived the project|wrote the manuscript|supervised and funded the project	supervised and funded the project	-	Funding acquisition|Supervision	YES
5852646	29335281	PGM	2	designed and carried out experiments|wrote the manuscript	designed and carried out experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5852646	29335281	PGM	2	designed and carried out experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5852646	29335281	RAI	2	designed and carried out informatic analyses|supervised and funded the project	designed and carried out informatic analyses	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5852646	29335281	RAI	2	designed and carried out informatic analyses|supervised and funded the project	supervised and funded the project	-	Funding acquisition|Supervision	YES
6332635	30646926	All authors	2	were involved in the study|reviewed the manuscript and approved the final version prior to submission	were involved in the study	-	-	NO
6332635	30646926	All authors	2	were involved in the study|reviewed the manuscript and approved the final version prior to submission	reviewed the manuscript and approved the final version prior to submission	Wrote the paper	Writing - Review & Editing	YES
6332635	30646926	JR	2	conceived and designed the study|constructed the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6332635	30646926	JR	2	conceived and designed the study|constructed the manuscript	constructed the manuscript	Performed the experiments	Investigation	YES
6332635	30646926	MW	2	conceived and designed the study|was centrally involved with data collection|constructed the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6332635	30646926	MW	2	conceived and designed the study|was centrally involved with data collection|constructed the manuscript	was centrally involved with data collection	Performed the experiments	Investigation	YES
6332635	30646926	MW	2	conceived and designed the study|was centrally involved with data collection|constructed the manuscript	constructed the manuscript	Performed the experiments	Investigation	YES
1955831	17848987	AV	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1955831	17848987	BM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1955831	17848987	BM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1955831	17848987	BM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1955831	17848987	FM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1955831	17848987	JL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1955831	17848987	JL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1955831	17848987	JL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1955831	17848987	LL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1955831	17848987	MP	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1955831	17848987	MP	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1955831	17848987	RR	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
6270673	24694652	Both Chenghao Tang	2	were also involved in drafting the manuscript	were also involved in drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
6270673	24694652	Fang Wu	2	carried out the elemental analysis	carried out the elemental analysis	Performed the experiments	Investigation	YES
6270673	24694652	HREI	2	spectral analyses	spectral analyses	Analyzed the data	Formal analysis	YES
6270673	24694652	Han Xiao	2	was involved in synthesis, characterization experiments and drafting manuscript	was involved in synthesis, characterization experiments and drafting manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6270673	24694652	Li Shi	2	performed the antifungal tests	performed the antifungal tests	Performed the experiments	Investigation	YES
6270673	24694652	Shihu Su	2	performed the antifungal tests	performed the antifungal tests	Performed the experiments	Investigation	YES
6270673	24694652	Zhiwei Chen	2	were also involved in drafting the manuscript	were also involved in drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
4416760	25932911	DC	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416760	25932911	DC	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416760	25932911	LAP	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416760	25932911	LAP	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416760	25932911	NP	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416760	25932911	NP	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416760	25932911	RWM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416760	25932911	RWM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416760	25932911	RWM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416760	25932911	RWM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4685591	26598735	Both authors	2	critically revised the paper and approved the final version	critically revised the paper and approved the final version	Wrote the paper	Writing - Review & Editing	YES
4685591	26598735	I.J.	2	was responsible for the design and execution of the simulation studies	was responsible for the design and execution of the simulation studies	Conceived and designed the experiments|Performed the experiments	Formal analysis|Investigation|Methodology	YES
5514007	28724262	All	PLoS52	data and materials cited on the manuscript are freely available for the scientific community	data and materials cited on the manuscript are freely available for the scientific community	-	-	NO
5514007	28724262	All authors	PLoS52	read and approved the final manuscript|gave the consented for publication	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5514007	28724262	All authors	PLoS52	read and approved the final manuscript|gave the consented for publication	gave the consented for publication	-	-	NO
5514007	28724262	FJO	PLoS52	initiated and designed the study|contributed with reagents/materials|analyzed the data and wrote the paper	initiated and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5514007	28724262	FJO	PLoS52	initiated and designed the study|contributed with reagents/materials|analyzed the data and wrote the paper	contributed with reagents/materials	Contributed reagents/materials/analysis tools	Resources	YES
5514007	28724262	FJO	PLoS52	initiated and designed the study|contributed with reagents/materials|analyzed the data and wrote the paper	analyzed the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5514007	28724262	JF	PLoS52	initiated and designed the study|performed the experiments|analyzed the data and wrote the paper	initiated and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5514007	28724262	JF	PLoS52	initiated and designed the study|performed the experiments|analyzed the data and wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5514007	28724262	JF	PLoS52	initiated and designed the study|performed the experiments|analyzed the data and wrote the paper	analyzed the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5514007	28724262	MH	PLoS52	initiated and designed the study|contributed with reagents/materials|analyzed the data and wrote the paper	initiated and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5514007	28724262	MH	PLoS52	initiated and designed the study|contributed with reagents/materials|analyzed the data and wrote the paper	contributed with reagents/materials	Contributed reagents/materials/analysis tools	Resources	YES
5514007	28724262	MH	PLoS52	initiated and designed the study|contributed with reagents/materials|analyzed the data and wrote the paper	analyzed the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5514007	28724262	MM	PLoS52	initiated and designed the study|analyzed the data and wrote the paper	initiated and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5514007	28724262	MM	PLoS52	initiated and designed the study|analyzed the data and wrote the paper	analyzed the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5514007	28724262	The authors	PLoS52	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
1955832	17848994	BP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1955832	17848994	BP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1955832	17848994	BP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1955832	17848994	JJ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1955832	17848994	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1955832	17848994	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1955832	17848994	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1955832	17848994	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5731604	29244004	LL	2	designed the study, conceived method formulation, analyzed data and wrote the paper	designed the study, conceived method formulation, analyzed data and wrote the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
5731604	29244004	PA	2	implemented data collection, method formulation and analysis and interpretation of results, and wrote the paper	implemented data collection, method formulation and analysis and interpretation of results, and wrote the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
5797638	29441080	FL	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5797638	29441080	FL	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5797638	29441080	JC	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5797638	29441080	JC	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5797638	29441080	JL	PLoS52	wrote the paper with contributions from all the authors	wrote the paper with contributions from all the authors	Wrote the paper	Writing - Original Draft	YES
5797638	29441080	KF	PLoS52	designed the research|performed the experiments|analyzed the data|wrote the paper with contributions from all the authors	designed the research	Conceived and designed the experiments	Methodology	YES
5797638	29441080	KF	PLoS52	designed the research|performed the experiments|analyzed the data|wrote the paper with contributions from all the authors	performed the experiments	Performed the experiments	Investigation	YES
5797638	29441080	KF	PLoS52	designed the research|performed the experiments|analyzed the data|wrote the paper with contributions from all the authors	analyzed the data	Analyzed the data	Formal analysis	YES
5797638	29441080	KF	PLoS52	designed the research|performed the experiments|analyzed the data|wrote the paper with contributions from all the authors	wrote the paper with contributions from all the authors	Wrote the paper	Writing - Original Draft	YES
5797638	29441080	SC	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5797638	29441080	WeiL	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5797638	29441080	WenL	PLoS52	designed the research|wrote the paper with contributions from all the authors	designed the research	Conceived and designed the experiments	Methodology	YES
5797638	29441080	WenL	PLoS52	designed the research|wrote the paper with contributions from all the authors	wrote the paper with contributions from all the authors	Wrote the paper	Writing - Original Draft	YES
5797638	29441080	ZL	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
6341721	30665439	CS	2	carried out all the experimental work and statistical analysis	carried out all the experimental work and statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6341721	30665439	MY	2	carried out all the experimental work and statistical analysis|participated in the manuscript design, interpretation and preparation of the manuscript	carried out all the experimental work and statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6341721	30665439	MY	2	carried out all the experimental work and statistical analysis|participated in the manuscript design, interpretation and preparation of the manuscript	participated in the manuscript design, interpretation and preparation of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6341721	30665439	PB	2	conceived and designed the study|carried out all the experimental work and statistical analysis|participated in the manuscript design, interpretation and preparation of the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6341721	30665439	PB	2	conceived and designed the study|carried out all the experimental work and statistical analysis|participated in the manuscript design, interpretation and preparation of the manuscript	carried out all the experimental work and statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6341721	30665439	PB	2	conceived and designed the study|carried out all the experimental work and statistical analysis|participated in the manuscript design, interpretation and preparation of the manuscript	participated in the manuscript design, interpretation and preparation of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6341721	30665439	PY	2	carried out all the experimental work and statistical analysis	carried out all the experimental work and statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6341721	30665439	SK	2	carried out all the experimental work and statistical analysis	carried out all the experimental work and statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6341721	30665439	TG	2	participated in the manuscript design, interpretation and preparation of the manuscript	participated in the manuscript design, interpretation and preparation of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6341721	30665439	WN	2	carried out all the experimental work and statistical analysis	carried out all the experimental work and statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5852647	29449323	AH	2	prepared protein samples	prepared protein samples	Performed the experiments	Investigation	YES
5852647	29449323	All authors	2	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5852647	29449323	BS	2	designed smfret experiments|wrote the manuscript	designed smfret experiments	Conceived and designed the experiments	Methodology	YES
5852647	29449323	BS	2	designed smfret experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5852647	29449323	CM	2	designed nmr experiments|conducted nmr experiments|prepared protein samples|wrote the manuscript	designed nmr experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5852647	29449323	CM	2	designed nmr experiments|conducted nmr experiments|prepared protein samples|wrote the manuscript	conducted nmr experiments	Performed the experiments	Investigation	YES
5852647	29449323	CM	2	designed nmr experiments|conducted nmr experiments|prepared protein samples|wrote the manuscript	prepared protein samples	Performed the experiments	Investigation	YES
5852647	29449323	CM	2	designed nmr experiments|conducted nmr experiments|prepared protein samples|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5852647	29449323	FA	2	designed and conducted rna silencing assays	designed and conducted rna silencing assays	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5852647	29449323	FH-TA	2	designed nmr experiments|wrote the manuscript	designed nmr experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5852647	29449323	FH-TA	2	designed nmr experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5852647	29449323	GJ	2	designed epr experiments	designed epr experiments	Conceived and designed the experiments	Methodology	YES
5852647	29449323	GM	2	designed nmr experiments|conducted nmr experiments|designed epr experiments|prepared protein samples|designed and performed dicing assays|wrote the manuscript	designed nmr experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5852647	29449323	GM	2	designed nmr experiments|conducted nmr experiments|designed epr experiments|prepared protein samples|designed and performed dicing assays|wrote the manuscript	conducted nmr experiments	Performed the experiments	Investigation	YES
5852647	29449323	GM	2	designed nmr experiments|conducted nmr experiments|designed epr experiments|prepared protein samples|designed and performed dicing assays|wrote the manuscript	designed epr experiments	Conceived and designed the experiments	Methodology	YES
5852647	29449323	GM	2	designed nmr experiments|conducted nmr experiments|designed epr experiments|prepared protein samples|designed and performed dicing assays|wrote the manuscript	prepared protein samples	Performed the experiments	Investigation	YES
5852647	29449323	GM	2	designed nmr experiments|conducted nmr experiments|designed epr experiments|prepared protein samples|designed and performed dicing assays|wrote the manuscript	designed and performed dicing assays	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5852647	29449323	GM	2	designed nmr experiments|conducted nmr experiments|designed epr experiments|prepared protein samples|designed and performed dicing assays|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5852647	29449323	JH	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5852647	29449323	JW	2	designed and conducted rna silencing assays	designed and conducted rna silencing assays	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5852647	29449323	MY	2	designed epr experiments|conducted epr experiments|wrote the manuscript	designed epr experiments	Conceived and designed the experiments	Methodology	YES
5852647	29449323	MY	2	designed epr experiments|conducted epr experiments|wrote the manuscript	conducted epr experiments	Performed the experiments	Investigation	YES
5852647	29449323	MY	2	designed epr experiments|conducted epr experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5852647	29449323	SLBK	2	designed smfret experiments|conducted smfret experiments|wrote the manuscript	designed smfret experiments	Conceived and designed the experiments	Methodology	YES
5852647	29449323	SLBK	2	designed smfret experiments|conducted smfret experiments|wrote the manuscript	conducted smfret experiments	Performed the experiments	Investigation	YES
5852647	29449323	SLBK	2	designed smfret experiments|conducted smfret experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4416761	25933037	AA	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416761	25933037	AA	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416761	25933037	AA	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416761	25933037	AH	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416761	25933037	AH	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416761	25933037	FZB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416761	25933037	JP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416761	25933037	JP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4416761	25933037	JP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416761	25933037	JW	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416761	25933037	JW	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416761	25933037	JdVI	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416761	25933037	MB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4416761	25933037	MB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416761	25933037	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416761	25933037	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416761	25933037	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416761	25933037	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5517391	28728309	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5517391	28728309	JHW	2	participated in the design of the study and supervised overall experiments	participated in the design of the study and supervised overall experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Supervision	YES
5517391	28728309	JHY	2	participated in the design of the study and supervised overall experiments	participated in the design of the study and supervised overall experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Supervision	YES
5517391	28728309	QFG	2	participated in the sequence alignment and preparing figures	participated in the sequence alignment and preparing figures	Performed the experiments	Investigation|Visualization	YES
5517391	28728309	XMW	2	jointly wrote the manuscript	jointly wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5517391	28728309	XW	2	performed the immunizations and the animal experiments	performed the immunizations and the animal experiments	Performed the experiments	Investigation	YES
5517391	28728309	YH	2	served and participated in this work as professional technician	served and participated in this work as professional technician	Performed the experiments	Investigation	YES
5731608	29244009	AA	2	implemented and tested the algorithms	implemented and tested the algorithms	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5731608	29244009	AM	2	implemented and tested the algorithms	implemented and tested the algorithms	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5731608	29244009	AZ	2	designed and implemented the algorithms, analyzed the results and supervised the research	designed and implemented the algorithms, analyzed the results and supervised the research	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Methodology|Software|Supervision	YES
5731608	29244009	OG	2	designed, implemented and tested the algorithms	designed, implemented and tested the algorithms	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5731608	29244009	PS	2	designed and implemented the algorithms, analyzed the results and supervised the research	designed and implemented the algorithms, analyzed the results and supervised the research	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Methodology|Software|Supervision	YES
5731608	29244009	SK	2	designed, implemented and tested the algorithms	designed, implemented and tested the algorithms	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5731608	29244009	YK	2	designed the algorithms and analyzed the algorithms results	designed the algorithms and analyzed the algorithms results	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Software	YES
4760138	26880840	A.D.	2	conceived the study in a workshop setting	conceived the study in a workshop setting	Conceived and designed the experiments	Conceptualization	YES
4760138	26880840	B.L.W.	2	conceived the study in a workshop setting	conceived the study in a workshop setting	Conceived and designed the experiments	Conceptualization	YES
4760138	26880840	C.D.H.	2	conceived the study in a workshop setting|led drafting of the paper and all authors provided input and helped interpret the results	conceived the study in a workshop setting	Conceived and designed the experiments	Conceptualization	YES
4760138	26880840	C.D.H.	2	conceived the study in a workshop setting|led drafting of the paper and all authors provided input and helped interpret the results	led drafting of the paper and all authors provided input and helped interpret the results	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4760138	26880840	C.M.E.	2	conceived the study in a workshop setting|developed figure 2 and the process explanation	conceived the study in a workshop setting	Conceived and designed the experiments	Conceptualization	YES
4760138	26880840	C.M.E.	2	conceived the study in a workshop setting|developed figure 2 and the process explanation	developed figure 2 and the process explanation	-	Visualization	YES
4760138	26880840	G.L.	2	who led the coding/development of the surveillance tools	who led the coding/development of the surveillance tools	-	-	NO
4760138	26880840	J.D.S.	2	conceived the study in a workshop setting|led drafting of the paper and all authors provided input and helped interpret the results	conceived the study in a workshop setting	Conceived and designed the experiments	Conceptualization	YES
4760138	26880840	J.D.S.	2	conceived the study in a workshop setting|led drafting of the paper and all authors provided input and helped interpret the results	led drafting of the paper and all authors provided input and helped interpret the results	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4760138	26880840	J.M.	2	conceived the study in a workshop setting|developed figure 2 and the process explanation|developed figure 2 and the process explanation|led drafting of the paper and all authors provided input and helped interpret the results	conceived the study in a workshop setting	Conceived and designed the experiments	Conceptualization	YES
4760138	26880840	J.M.	2	conceived the study in a workshop setting|developed figure 2 and the process explanation|developed figure 2 and the process explanation|led drafting of the paper and all authors provided input and helped interpret the results	developed figure 2 and the process explanation	-	Visualization	YES
4760138	26880840	J.M.	2	conceived the study in a workshop setting|developed figure 2 and the process explanation|developed figure 2 and the process explanation|led drafting of the paper and all authors provided input and helped interpret the results	developed figure 2 and the process explanation	-	Visualization	YES
4760138	26880840	J.M.	2	conceived the study in a workshop setting|developed figure 2 and the process explanation|developed figure 2 and the process explanation|led drafting of the paper and all authors provided input and helped interpret the results	led drafting of the paper and all authors provided input and helped interpret the results	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4760138	26880840	R.v.H.	2	who led the coding/development of the surveillance tools	who led the coding/development of the surveillance tools	-	-	NO
4760138	26880840	S.F.H.	2	conceived the study in a workshop setting	conceived the study in a workshop setting	Conceived and designed the experiments	Conceptualization	YES
1955833	17786223	JW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1955833	17786223	JW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1955833	17786223	JW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1955833	17786223	JW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1955833	17786223	JZ	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1955833	17786223	JZ	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1955833	17786223	JZ	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1955833	17786223	LK	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1955833	17786223	LK	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1955833	17786223	LW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1955833	17786223	ON	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1955833	17786223	ON	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1955833	17786223	SZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5797647	29441083	EE	7	conducted data analyses and prepared the first draft	conducted data analyses and prepared the first draft	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5797647	29441083	MP	7	provided seeds of the mapping panel and reviewed the manuscript	provided seeds of the mapping panel and reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5797647	29441083	MR	7	conceived the study, designed, and conducted both field and greenhouse experiments, and reviewed the manuscript	conceived the study, designed, and conducted both field and greenhouse experiments, and reviewed the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Writing - Review & Editing	YES
4630369	26576420	Chao Ma	2	contributed equally to this work	contributed equally to this work	-	-	NO
4630369	26576420	Renjian Zou	2	contributed equally to this work	contributed equally to this work	-	-	NO
4630369	26576420	Yanlei Huo	2	contributed equally to this work	contributed equally to this work	-	-	NO
6364418	30728074	All authors	2	participated in the conception and design of the study|equally contributed to the data analysis|gave approval of the final manuscript, and they were equally involved in the editing and revising of the final manuscript draft	participated in the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6364418	30728074	All authors	2	participated in the conception and design of the study|equally contributed to the data analysis|gave approval of the final manuscript, and they were equally involved in the editing and revising of the final manuscript draft	equally contributed to the data analysis	Analyzed the data	Formal analysis	YES
6364418	30728074	All authors	2	participated in the conception and design of the study|equally contributed to the data analysis|gave approval of the final manuscript, and they were equally involved in the editing and revising of the final manuscript draft	gave approval of the final manuscript, and they were equally involved in the editing and revising of the final manuscript draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6364418	30728074	CMS	2	collected data and recruited subjects|carried out all dietary analyses	collected data and recruited subjects	Performed the experiments	Investigation	YES
6364418	30728074	CMS	2	collected data and recruited subjects|carried out all dietary analyses	carried out all dietary analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6364418	30728074	ECH	2	collected data and recruited subjects|carried out all dietary analyses	collected data and recruited subjects	Performed the experiments	Investigation	YES
6364418	30728074	ECH	2	collected data and recruited subjects|carried out all dietary analyses	carried out all dietary analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6364418	30728074	JLK	2	collected data and recruited subjects|wrote the manuscript|carried out all dietary analyses	collected data and recruited subjects	Performed the experiments	Investigation	YES
6364418	30728074	JLK	2	collected data and recruited subjects|wrote the manuscript|carried out all dietary analyses	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6364418	30728074	JLK	2	collected data and recruited subjects|wrote the manuscript|carried out all dietary analyses	carried out all dietary analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6364418	30728074	TJH	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5881629	29507080	AC	2	performed the single-molecule experiments	performed the single-molecule experiments	Performed the experiments	Investigation	YES
5881629	29507080	All authors	2	discussed the results and commented on the manuscript	discussed the results and commented on the manuscript	-	-	NO
5881629	29507080	EBG	2	purified the proteins and performed the biochemical analysis of the protein samples	purified the proteins and performed the biochemical analysis of the protein samples	Performed the experiments	Investigation	YES
5881629	29507080	EJGP	2	wrote the manuscript|conceived the project and led the research	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5881629	29507080	EJGP	2	wrote the manuscript|conceived the project and led the research	conceived the project and led the research	Conceived and designed the experiments	Conceptualization	YES
5881629	29507080	GJLW	2	wrote the manuscript|conceived the project and led the research	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5881629	29507080	GJLW	2	wrote the manuscript|conceived the project and led the research	conceived the project and led the research	Conceived and designed the experiments	Conceptualization	YES
5881629	29507080	IB	2	performed the single-molecule experiments|wrote the manuscript	performed the single-molecule experiments	Performed the experiments	Investigation	YES
5881629	29507080	IB	2	performed the single-molecule experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5881629	29507080	LP	2	performed the crystallization and x-ray crystal structure determination|wrote the manuscript|conceived the project and led the research	performed the crystallization and x-ray crystal structure determination	Performed the experiments	Investigation	YES
5881629	29507080	LP	2	performed the crystallization and x-ray crystal structure determination|wrote the manuscript|conceived the project and led the research	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5881629	29507080	LP	2	performed the crystallization and x-ray crystal structure determination|wrote the manuscript|conceived the project and led the research	conceived the project and led the research	Conceived and designed the experiments	Conceptualization	YES
5881629	29507080	MM	2	purified the proteins and performed the biochemical analysis of the protein samples|conceived the project and led the research	purified the proteins and performed the biochemical analysis of the protein samples	Performed the experiments	Investigation	YES
5881629	29507080	MM	2	purified the proteins and performed the biochemical analysis of the protein samples|conceived the project and led the research	conceived the project and led the research	Conceived and designed the experiments	Conceptualization	YES
5881629	29507080	TM	2	performed the crystallization and x-ray crystal structure determination|purified the proteins and performed the biochemical analysis of the protein samples	performed the crystallization and x-ray crystal structure determination	Performed the experiments	Investigation	YES
5881629	29507080	TM	2	performed the crystallization and x-ray crystal structure determination|purified the proteins and performed the biochemical analysis of the protein samples	purified the proteins and performed the biochemical analysis of the protein samples	Performed the experiments	Investigation	YES
4416762	25932914	AC	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416762	25932914	CL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416762	25932914	CL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416762	25932914	CL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416762	25932914	HS	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416762	25932914	MM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416762	25932914	MM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416762	25932914	MM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416762	25932914	TK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416762	25932914	TK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416762	25932914	TK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416762	25932914	TP	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416762	25932914	TP	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270675	24838076	Jianchun Guo	2	were responsible for the programs and all experiments, critically revised the manuscript and provided final approval for the article	were responsible for the programs and all experiments, critically revised the manuscript and provided final approval for the article	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
6270675	24838076	Jiao Liu	2	worked on primer design, technical and informatics analyses of these genes	worked on primer design, technical and informatics analyses of these genes	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis	YES
6270675	24838076	Mengting Geng	2	worked on the preparation of the studied materials and gene cloning	worked on the preparation of the studied materials and gene cloning	Performed the experiments	Investigation	YES
6270675	24838076	Ruimei Li	2	worked on primer design, technical and informatics analyses of these genes	worked on primer design, technical and informatics analyses of these genes	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis	YES
6270675	24838076	Xiaohui Wu	2	were responsible for all aspects of the research, including experimental design, data acquisition and analysis, and manuscript preparation	were responsible for all aspects of the research, including experimental design, data acquisition and analysis, and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
6270675	24838076	Xinwen Hu	2	were responsible for the programs and all experiments, critically revised the manuscript and provided final approval for the article	were responsible for the programs and all experiments, critically revised the manuscript and provided final approval for the article	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
6270675	24838076	Yuan Yao	2	were responsible for all aspects of the research, including experimental design, data acquisition and analysis, and manuscript preparation	were responsible for all aspects of the research, including experimental design, data acquisition and analysis, and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
1955834	17848995	SS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5735816	29258433	AB	2	collected samples	collected samples	Performed the experiments	Investigation	YES
5735816	29258433	AHF	2	collected samples	collected samples	Performed the experiments	Investigation	YES
5735816	29258433	AN	2	contributed to the design of the analyses	contributed to the design of the analyses	Conceived and designed the experiments|Analyzed the data	Formal analysis	YES
5735816	29258433	ASA	2	performed most of the analyses|wrote the manuscript	performed most of the analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5735816	29258433	ASA	2	performed most of the analyses|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5735816	29258433	BLG	2	designed the study, analyses and the method|contributed to the analyses|wrote the manuscript	designed the study, analyses and the method	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5735816	29258433	BLG	2	designed the study, analyses and the method|contributed to the analyses|wrote the manuscript	contributed to the analyses	Analyzed the data	Formal analysis	YES
5735816	29258433	BLG	2	designed the study, analyses and the method|contributed to the analyses|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5735816	29258433	CV	2	collected samples	collected samples	Performed the experiments	Investigation	YES
5735816	29258433	GS	2	contributed to the design of the analyses	contributed to the design of the analyses	Conceived and designed the experiments|Analyzed the data	Formal analysis	YES
5735816	29258433	ISP	2	designed the study, analyses and the method|performed most of the analyses|wrote the manuscript	designed the study, analyses and the method	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5735816	29258433	ISP	2	designed the study, analyses and the method|performed most of the analyses|wrote the manuscript	performed most of the analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5735816	29258433	ISP	2	designed the study, analyses and the method|performed most of the analyses|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5735816	29258433	JHR	2	performed the experimental analyses	performed the experimental analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5735816	29258433	JN	2	collected samples	collected samples	Performed the experiments	Investigation	YES
5735816	29258433	JQ	2	performed most of the analyses|wrote the manuscript	performed most of the analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5735816	29258433	JQ	2	performed most of the analyses|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5735816	29258433	LFKK	2	contributed to the analyses	contributed to the analyses	Analyzed the data	Formal analysis	YES
5735816	29258433	OR	2	performed the experimental analyses|contributed to the design of the analyses	performed the experimental analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5735816	29258433	OR	2	performed the experimental analyses|contributed to the design of the analyses	contributed to the design of the analyses	Conceived and designed the experiments|Analyzed the data	Formal analysis	YES
5735816	29258433	RW	2	collected samples	collected samples	Performed the experiments	Investigation	YES
5735816	29258433	SNP	2	diversity analysis	diversity analysis	-	-	NO
5735816	29258433	TMB	2	designed the study, analyses and the method|wrote the manuscript	designed the study, analyses and the method	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5735816	29258433	TMB	2	designed the study, analyses and the method|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5735816	29258433	ZF	2	collected samples	collected samples	Performed the experiments	Investigation	YES
5735816	29258433	all authors	2	read and approved the manuscript	read and approved the manuscript	-	-	NO
5524659	28747041	Both authors	2	contributed to the design of the experiments|read and approved the final manuscript	contributed to the design of the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5524659	28747041	Both authors	2	contributed to the design of the experiments|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5524659	28747041	MZT	2	performed the experiment, collected the data, analysed and interpreted the data, and wrote the manuscript	performed the experiment, collected the data, analysed and interpreted the data, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5524659	28747041	SQL	2	analysed and interpreted the data, and wrote the manuscript	analysed and interpreted the data, and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4760142	26880844	C.D.H.	PLoS52	designed the field survey and conducted the sampling|designed and conducted the temperature experiment with|analysed the data|wrote the paper with	designed the field survey and conducted the sampling	Conceived and designed the experiments|Performed the experiments	Investigation	YES
4760142	26880844	C.D.H.	PLoS52	designed the field survey and conducted the sampling|designed and conducted the temperature experiment with|analysed the data|wrote the paper with	designed and conducted the temperature experiment with	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4760142	26880844	C.D.H.	PLoS52	designed the field survey and conducted the sampling|designed and conducted the temperature experiment with|analysed the data|wrote the paper with	analysed the data	Analyzed the data	Formal analysis	YES
4760142	26880844	C.D.H.	PLoS52	designed the field survey and conducted the sampling|designed and conducted the temperature experiment with|analysed the data|wrote the paper with	wrote the paper with	Wrote the paper	Writing - Original Draft	YES
4760142	26880844	J.E.	PLoS52	designed the field survey and conducted the sampling	designed the field survey and conducted the sampling	Conceived and designed the experiments|Performed the experiments	Investigation	YES
4760142	26880844	J.M.	PLoS52	to explain patterns|wrote the paper with	to explain patterns	-	-	NO
4760142	26880844	J.M.	PLoS52	to explain patterns|wrote the paper with	wrote the paper with	Wrote the paper	Writing - Original Draft	YES
4760142	26880844	K.P.	PLoS52	designed the field survey and conducted the sampling	designed the field survey and conducted the sampling	Conceived and designed the experiments|Performed the experiments	Investigation	YES
4760142	26880844	M.E.	PLoS52	designed the field survey and conducted the sampling|designed and conducted the temperature experiment with|analysed the data|wrote the paper with	designed the field survey and conducted the sampling	Conceived and designed the experiments|Performed the experiments	Investigation	YES
4760142	26880844	M.E.	PLoS52	designed the field survey and conducted the sampling|designed and conducted the temperature experiment with|analysed the data|wrote the paper with	designed and conducted the temperature experiment with	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4760142	26880844	M.E.	PLoS52	designed the field survey and conducted the sampling|designed and conducted the temperature experiment with|analysed the data|wrote the paper with	analysed the data	Analyzed the data	Formal analysis	YES
4760142	26880844	M.E.	PLoS52	designed the field survey and conducted the sampling|designed and conducted the temperature experiment with|analysed the data|wrote the paper with	wrote the paper with	Wrote the paper	Writing - Original Draft	YES
4760142	26880844	M.L.G.	PLoS52	analysed the data|wrote the paper with	analysed the data	Analyzed the data	Formal analysis	YES
4760142	26880844	M.L.G.	PLoS52	analysed the data|wrote the paper with	wrote the paper with	Wrote the paper	Writing - Original Draft	YES
4760142	26880844	M.T.	PLoS52	designed the field survey and conducted the sampling|designed and conducted the temperature experiment with	designed the field survey and conducted the sampling	Conceived and designed the experiments|Performed the experiments	Investigation	YES
4760142	26880844	M.T.	PLoS52	designed the field survey and conducted the sampling|designed and conducted the temperature experiment with	designed and conducted the temperature experiment with	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4760142	26880844	N.R.	PLoS52	designed and conducted the temperature experiment with	designed and conducted the temperature experiment with	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4760142	26880844	R.Y.	PLoS52	designed the field survey and conducted the sampling|analysed the data|wrote the paper with	designed the field survey and conducted the sampling	Conceived and designed the experiments|Performed the experiments	Investigation	YES
4760142	26880844	R.Y.	PLoS52	designed the field survey and conducted the sampling|analysed the data|wrote the paper with	analysed the data	Analyzed the data	Formal analysis	YES
4760142	26880844	R.Y.	PLoS52	designed the field survey and conducted the sampling|analysed the data|wrote the paper with	wrote the paper with	Wrote the paper	Writing - Original Draft	YES
4760142	26880844	RY	PLoS52	assisted with the designed and conducted the temperature experiment with	assisted with the designed and conducted the temperature experiment with	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4760142	26880844	S.F.	PLoS52	designed the field survey and conducted the sampling	designed the field survey and conducted the sampling	Conceived and designed the experiments|Performed the experiments	Investigation	YES
4760142	26880844	all other authors	PLoS52	assisted with the wrote the paper with	assisted with the wrote the paper with	Wrote the paper	Writing - Original Draft	YES
6366059	30728061	BK	2	contributed to study design, data collection, data analysis, major contribution to the writing of the manuscript	contributed to study design, data collection, data analysis, major contribution to the writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
6366059	30728061	CM	2	contributed to the study design, data collection, moderate editing of manuscript, and procurement of funds	contributed to the study design, data collection, moderate editing of manuscript, and procurement of funds	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Methodology|Resources|Writing - Review & Editing	YES
6366059	30728061	CW	2	contributed with data collection, assisted with data analysis, and moderate contributions to the editing of the manuscript	contributed with data collection, assisted with data analysis, and moderate contributions to the editing of the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Review & Editing	YES
6366059	30728061	EB	2	contributed to data collection, performed hrv analysis and interpretation, blood assay analysis, conducted literature review, and major contribution to the writing of the manuscript	contributed to data collection, performed hrv analysis and interpretation, blood assay analysis, conducted literature review, and major contribution to the writing of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
6366059	30728061	JM	2	contributed to study design, data statistical analysis, and moderate editing of manuscript	contributed to study design, data statistical analysis, and moderate editing of manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Review & Editing	YES
6366059	30728061	PB	2	contributed to study design, data collection, biomarker analysis, and moderate editing of the manuscript	contributed to study design, data collection, biomarker analysis, and moderate editing of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Review & Editing	YES
6366059	30728061	ZG	2	significant contribution to editing of the manuscript	significant contribution to editing of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5797689	29441076	AM	2	devised the field experiments, adjusted the field data and provided plant material	devised the field experiments, adjusted the field data and provided plant material	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceptualization|Investigation|Resources	YES
5797689	29441076	AT	2	conducted the srna seq experiments|interpreted all data and wrote the manuscript	conducted the srna seq experiments	Performed the experiments	Investigation	YES
5797689	29441076	AT	2	conducted the srna seq experiments|interpreted all data and wrote the manuscript	interpreted all data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5797689	29441076	All authors	2	provided intellectual input and approved the final manuscript	provided intellectual input and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5797689	29441076	DR	2	conducted the srna seq experiments	conducted the srna seq experiments	Performed the experiments	Investigation	YES
5797689	29441076	FS	2	performed the bioinformatics and statistical analyses|interpreted all data and wrote the manuscript	performed the bioinformatics and statistical analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5797689	29441076	FS	2	performed the bioinformatics and statistical analyses|interpreted all data and wrote the manuscript	interpreted all data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5797689	29441076	HD	2	interpreted all data and wrote the manuscript	interpreted all data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5797689	29441076	MF	2	contributed to statistical analyses	contributed to statistical analyses	Analyzed the data	Formal analysis	YES
5797689	29441076	RG-D	2	interpreted all data and wrote the manuscript	interpreted all data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5797689	29441076	SE	2	conducted the srna seq experiments	conducted the srna seq experiments	Performed the experiments	Investigation	YES
5797689	29441076	SS	2	devised and planned the srna seq experiments and association studies|interpreted all data and wrote the manuscript	devised and planned the srna seq experiments and association studies	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5797689	29441076	SS	2	devised and planned the srna seq experiments and association studies|interpreted all data and wrote the manuscript	interpreted all data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5797689	29441076	TS	2	devised the field experiments, adjusted the field data and provided plant material	devised the field experiments, adjusted the field data and provided plant material	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceptualization|Investigation|Resources	YES
4416763	25933068	AF	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416763	25933068	AF	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416763	25933068	HV	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416763	25933068	HV	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416763	25933068	HV	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416763	25933068	HV	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416763	25933068	IH	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416763	25933068	IH	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416763	25933068	JS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416763	25933068	JS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416763	25933068	JS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416763	25933068	MC	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416763	25933068	MHM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416763	25933068	MHM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416763	25933068	MHM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416763	25933068	MM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416763	25933068	MM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416763	25933068	MM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416763	25933068	PD	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416763	25933068	PD	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416763	25933068	TM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416763	25933068	TM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416763	25933068	TM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416763	25933068	WE	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416763	25933068	WE	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5797756	29445384	All authors	2	listed have made a substantial, direct, and intellectual contribution to the work, and approved it for publication	listed have made a substantial, direct, and intellectual contribution to the work, and approved it for publication	-	-	NO
5897774	29510984	All authors	PLoS52	contributed to data analysis and commented on the manuscript	contributed to data analysis and commented on the manuscript	Analyzed the data	Formal analysis	YES
5897774	29510984	CG-C	PLoS52	designed and performed experiments	designed and performed experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5897774	29510984	EJK	PLoS52	contributed to the design of experiments	contributed to the design of experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5897774	29510984	FG	PLoS52	supervised experimental work|wrote the paper	supervised experimental work	Performed the experiments	Investigation|Supervision	YES
5897774	29510984	FG	PLoS52	supervised experimental work|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5897774	29510984	JWC	PLoS52	contributed to the design of experiments	contributed to the design of experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5897774	29510984	MM	PLoS52	designed and performed experiments	designed and performed experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5897774	29510984	MP	PLoS52	designed and performed experiments	designed and performed experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5897774	29510984	MWR	PLoS52	designed and performed experiments	designed and performed experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5897774	29510984	NH-D	PLoS52	designed and performed experiments	designed and performed experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5897774	29510984	NJ	PLoS52	designed and performed experiments	designed and performed experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5897774	29510984	RB	PLoS52	supervised experimental work|wrote the paper	supervised experimental work	Performed the experiments	Investigation|Supervision	YES
5897774	29510984	RB	PLoS52	supervised experimental work|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5897774	29510984	SGB	PLoS52	designed and performed experiments|wrote the paper	designed and performed experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5897774	29510984	SGB	PLoS52	designed and performed experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5897774	29510984	SJR	PLoS52	supervised experimental work|wrote the paper	supervised experimental work	Performed the experiments	Investigation|Supervision	YES
5897774	29510984	SJR	PLoS52	supervised experimental work|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5897774	29510984	SS	PLoS52	designed and performed experiments	designed and performed experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
1959117	17786224	AL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1959117	17786224	CC	PLoS5	Bred mice|Performed cell cycle analyses	Bred mice	-	-	NO
1959117	17786224	CC	PLoS5	Bred mice|Performed cell cycle analyses	Performed cell cycle analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
1959117	17786224	DL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1959117	17786224	MS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1959117	17786224	MS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1959117	17786224	MT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1959117	17786224	MT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1959117	17786224	MT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1959117	17786224	MT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1959117	17786224	PC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1959117	17786224	PS	PLoS5	Performed elisa	Performed elisa	Performed the experiments	Investigation	YES
1959117	17786224	SK	PLoS5	Performed the experiments|Performed the experiments|Wrote the paper|Wrote the paper|Performed elisa	Performed the experiments	Performed the experiments	Investigation	YES
1959117	17786224	SK	PLoS5	Performed the experiments|Performed the experiments|Wrote the paper|Wrote the paper|Performed elisa	Performed the experiments	Performed the experiments	Investigation	YES
1959117	17786224	SK	PLoS5	Performed the experiments|Performed the experiments|Wrote the paper|Wrote the paper|Performed elisa	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1959117	17786224	SK	PLoS5	Performed the experiments|Performed the experiments|Wrote the paper|Wrote the paper|Performed elisa	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1959117	17786224	SK	PLoS5	Performed the experiments|Performed the experiments|Wrote the paper|Wrote the paper|Performed elisa	Performed elisa	Performed the experiments	Investigation	YES
5735898	29258442	ARW	2	supervised the study, interpreted data and wrote the manuscript	supervised the study, interpreted data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Supervision|Writing - Original Draft	YES
5735898	29258442	AS	2	performed rna quality analysis and provided expert input in data analysis and critically revised the manuscript	performed rna quality analysis and provided expert input in data analysis and critically revised the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Review & Editing	YES
5735898	29258442	CH	2	performed animal experiments and gene ontology analysis	performed animal experiments and gene ontology analysis	Performed the experiments	Investigation	YES
5735898	29258442	DH	2	performed rna quality analysis and provided expert input in data analysis and critically revised the manuscript	performed rna quality analysis and provided expert input in data analysis and critically revised the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Review & Editing	YES
5735898	29258442	DM	2	performed animal experiments and gene ontology analysis	performed animal experiments and gene ontology analysis	Performed the experiments	Investigation	YES
5735898	29258442	FS	2	conceived and designed all experiments, analyzed data and wrote the manuscript	conceived and designed all experiments, analyzed data and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
5735898	29258442	TEK	2	performed animal experiments and gene ontology analysis	performed animal experiments and gene ontology analysis	Performed the experiments	Investigation	YES
6371469	30744654	AM	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6371469	30744654	AM	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
6371469	30744654	AM	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
6371469	30744654	AM	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6371469	30744654	All authors	PLoS52	read, commented on, and approved the final manuscript	read, commented on, and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6371469	30744654	JK	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
6371469	30744654	JK	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
6371469	30744654	KF	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6371469	30744654	KF	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
6371469	30744654	KF	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
6371469	30744654	MD	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6371469	30744654	MD	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
6371469	30744654	MD	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
6371469	30744654	SF	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
6371469	30744654	SF	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
6371469	30744654	SI	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6371469	30744654	SI	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
6371469	30744654	SI	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
6371469	30744654	SI	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5532177	28754034	EE	2	planned the experiments|supervised and carried out the experiments, analyzed the data and wrote the manuscript	planned the experiments	Conceived and designed the experiments	Conceptualization	YES
5532177	28754034	EE	2	planned the experiments|supervised and carried out the experiments, analyzed the data and wrote the manuscript	supervised and carried out the experiments, analyzed the data and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Supervision|Writing - Original Draft	YES
5532177	28754034	SAWB	2	planned the experiments|contributed by scientific discussions during the whole study	planned the experiments	Conceived and designed the experiments	Conceptualization	YES
5532177	28754034	SAWB	2	planned the experiments|contributed by scientific discussions during the whole study	contributed by scientific discussions during the whole study	-	-	NO
5532177	28754034	UK	2	contributed by scientific discussions during the whole study|acquired funding for the study	contributed by scientific discussions during the whole study	-	-	NO
5532177	28754034	UK	2	contributed by scientific discussions during the whole study|acquired funding for the study	acquired funding for the study	-	Funding acquisition	YES
6270677	25268715	H.L.	2	executed cytotoxic tests	executed cytotoxic tests	Performed the experiments	Investigation	YES
6270677	25268715	Y.K.S.	2	executed cytotoxic tests	executed cytotoxic tests	Performed the experiments	Investigation	YES
4630371	26576426	Feng Mao	2	contributed to the work equally	contributed to the work equally	-	-	NO
4630371	26576426	Yi Dong	2	contributed to the work equally	contributed to the work equally	-	-	NO
5797776	29445389	HH	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5797776	29445389	LF	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5797776	29445389	LZ	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5797776	29445389	QH	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5797776	29445389	TZ	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4416764	25933176	AMH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416764	25933176	AMH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416764	25933176	AMH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416764	25933176	CCC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4416764	25933176	CCC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416764	25933176	CRM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416764	25933176	CSL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4416764	25933176	CSL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416764	25933176	EJC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416764	25933176	EJC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416764	25933176	EJC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416764	25933176	HGO	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4416764	25933176	HGO	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416764	25933176	LO	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416764	25933176	LO	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416764	25933176	LO	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416764	25933176	ORS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4416764	25933176	ORS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416764	25933176	SIA	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1959118	17786192	QW	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1959118	17786192	QW	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1959118	17786192	QW	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1959118	17786192	YP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1959118	17786192	YP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1959118	17786192	YP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5533696	28759988	AH	2	have designed the work|carried out the experiment|analyzed the data and contributed to the statistical analysis|wrote the manuscript and reviewed the manuscript critically	have designed the work	Conceived and designed the experiments	-	YES
5533696	28759988	AH	2	have designed the work|carried out the experiment|analyzed the data and contributed to the statistical analysis|wrote the manuscript and reviewed the manuscript critically	carried out the experiment	Performed the experiments	Investigation	YES
5533696	28759988	AH	2	have designed the work|carried out the experiment|analyzed the data and contributed to the statistical analysis|wrote the manuscript and reviewed the manuscript critically	analyzed the data and contributed to the statistical analysis	Analyzed the data	Formal analysis	YES
5533696	28759988	AH	2	have designed the work|carried out the experiment|analyzed the data and contributed to the statistical analysis|wrote the manuscript and reviewed the manuscript critically	wrote the manuscript and reviewed the manuscript critically	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5533696	28759988	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5533696	28759988	MFL	2	have designed the work|analyzed the data and contributed to the statistical analysis|wrote the manuscript and reviewed the manuscript critically	have designed the work	Conceived and designed the experiments	-	YES
5533696	28759988	MFL	2	have designed the work|analyzed the data and contributed to the statistical analysis|wrote the manuscript and reviewed the manuscript critically	analyzed the data and contributed to the statistical analysis	Analyzed the data	Formal analysis	YES
5533696	28759988	MFL	2	have designed the work|analyzed the data and contributed to the statistical analysis|wrote the manuscript and reviewed the manuscript critically	wrote the manuscript and reviewed the manuscript critically	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5533696	28759988	MK	2	have designed the work|carried out the experiment|analyzed the data and contributed to the statistical analysis|wrote the manuscript and reviewed the manuscript critically	have designed the work	Conceived and designed the experiments	-	YES
5533696	28759988	MK	2	have designed the work|carried out the experiment|analyzed the data and contributed to the statistical analysis|wrote the manuscript and reviewed the manuscript critically	carried out the experiment	Performed the experiments	Investigation	YES
5533696	28759988	MK	2	have designed the work|carried out the experiment|analyzed the data and contributed to the statistical analysis|wrote the manuscript and reviewed the manuscript critically	analyzed the data and contributed to the statistical analysis	Analyzed the data	Formal analysis	YES
5533696	28759988	MK	2	have designed the work|carried out the experiment|analyzed the data and contributed to the statistical analysis|wrote the manuscript and reviewed the manuscript critically	wrote the manuscript and reviewed the manuscript critically	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5735905	29258446	All authors	2	contributed to the writing of the manuscript and approved the submission	contributed to the writing of the manuscript and approved the submission	Wrote the paper	Writing - Original Draft	YES
5735905	29258446	GBP	2	designed the experiments and revised the manuscript critically for important intellectual content	designed the experiments and revised the manuscript critically for important intellectual content	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5735905	29258446	KZ	2	did the data analysis and draft the manuscript	did the data analysis and draft the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5735905	29258446	LLG	2	designed the experiments and revised the manuscript critically for important intellectual content	designed the experiments and revised the manuscript critically for important intellectual content	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5735905	29258446	MO	2	designed the experiments and revised the manuscript critically for important intellectual content	designed the experiments and revised the manuscript critically for important intellectual content	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5735905	29258446	YHC	2	collected the samples and constructed the libraries	collected the samples and constructed the libraries	Performed the experiments	Investigation	YES
6270678	25365297	Guangmin Yao	PLoS52	performed research and analyzed the data	performed research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270678	25365297	Jinwen Zhang	PLoS52	designed the research|wrote the paper	designed the research	Conceived and designed the experiments	Methodology	YES
6270678	25365297	Jinwen Zhang	PLoS52	designed the research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270678	25365297	Junfen Zeng	PLoS52	performed research and analyzed the data	performed research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270678	25365297	Yongbo Xue	PLoS52	performed research and analyzed the data	performed research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270678	25365297	Yonghui Zhang	PLoS52	designed the research|wrote the paper	designed the research	Conceived and designed the experiments	Methodology	YES
6270678	25365297	Yonghui Zhang	PLoS52	designed the research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270678	25365297	Yongji Lai	PLoS52	performed research and analyzed the data	performed research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270678	25365297	Zengwei Luo	PLoS52	performed research and analyzed the data	performed research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5916273	28923826	AC	2	helped with the experiments and analysed the data with the	helped with the experiments and analysed the data with the	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5916273	28923826	AR	2	designed the experiments|performed the immuno-labelling experiments|purified trwb used for raising of the antibodies and purified the antibodies from the obtained serum|purified the deletion constructs|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5916273	28923826	AR	2	designed the experiments|performed the immuno-labelling experiments|purified trwb used for raising of the antibodies and purified the antibodies from the obtained serum|purified the deletion constructs|wrote the manuscript	performed the immuno-labelling experiments	Performed the experiments	Investigation	YES
5916273	28923826	AR	2	designed the experiments|performed the immuno-labelling experiments|purified trwb used for raising of the antibodies and purified the antibodies from the obtained serum|purified the deletion constructs|wrote the manuscript	purified trwb used for raising of the antibodies and purified the antibodies from the obtained serum	Performed the experiments	Investigation	YES
5916273	28923826	AR	2	designed the experiments|performed the immuno-labelling experiments|purified trwb used for raising of the antibodies and purified the antibodies from the obtained serum|purified the deletion constructs|wrote the manuscript	purified the deletion constructs	Performed the experiments	Investigation	YES
5916273	28923826	AR	2	designed the experiments|performed the immuno-labelling experiments|purified trwb used for raising of the antibodies and purified the antibodies from the obtained serum|purified the deletion constructs|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5916273	28923826	CF-R	2	purified the deletion constructs	purified the deletion constructs	Performed the experiments	Investigation	YES
5916273	28923826	EVO	2	supervised the em analysis	supervised the em analysis	-	Supervision	YES
5916273	28923826	GW	2	designed the experiments|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5916273	28923826	GW	2	designed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5916273	28923826	KT	2	helped with the experiments and analysed the data with the	helped with the experiments and analysed the data with the	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5916273	28923826	MT	2	purified trwb used for raising of the antibodies and purified the antibodies from the obtained serum|performed xl-ms experiments and analysed the data with the	purified trwb used for raising of the antibodies and purified the antibodies from the obtained serum	Performed the experiments	Investigation	YES
5916273	28923826	MT	2	purified trwb used for raising of the antibodies and purified the antibodies from the obtained serum|performed xl-ms experiments and analysed the data with the	performed xl-ms experiments and analysed the data with the	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5916273	28923826	RDH	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5916273	28923826	SC	2	designed the experiments|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5916273	28923826	SC	2	designed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6373093	30755234	AC	4	data were collected by|and manuscript preparation was undertaken by	data were collected by	Performed the experiments	Investigation	YES
6373093	30755234	AC	4	data were collected by|and manuscript preparation was undertaken by	and manuscript preparation was undertaken by	Wrote the paper	Writing - Original Draft	YES
6373093	30755234	ED	4	data were collected by|data were analyzed by|data interpretation were done by|and manuscript preparation was undertaken by	data were collected by	Performed the experiments	Investigation	YES
6373093	30755234	ED	4	data were collected by|data were analyzed by|data interpretation were done by|and manuscript preparation was undertaken by	data were analyzed by	Analyzed the data	Formal analysis	YES
6373093	30755234	ED	4	data were collected by|data were analyzed by|data interpretation were done by|and manuscript preparation was undertaken by	data interpretation were done by	Analyzed the data	Formal analysis	YES
6373093	30755234	ED	4	data were collected by|data were analyzed by|data interpretation were done by|and manuscript preparation was undertaken by	and manuscript preparation was undertaken by	Wrote the paper	Writing - Original Draft	YES
6373093	30755234	JB	4	The study was designed by|data interpretation were done by|and manuscript preparation was undertaken by	The study was designed by	Conceived and designed the experiments	Methodology	YES
6373093	30755234	JB	4	The study was designed by|data interpretation were done by|and manuscript preparation was undertaken by	data interpretation were done by	Analyzed the data	Formal analysis	YES
6373093	30755234	JB	4	The study was designed by|data interpretation were done by|and manuscript preparation was undertaken by	and manuscript preparation was undertaken by	Wrote the paper	Writing - Original Draft	YES
6373093	30755234	JC	4	data were collected by	data were collected by	Performed the experiments	Investigation	YES
6373093	30755234	JI	4	The study was designed by|and manuscript preparation was undertaken by	The study was designed by	Conceived and designed the experiments	Methodology	YES
6373093	30755234	JI	4	The study was designed by|and manuscript preparation was undertaken by	and manuscript preparation was undertaken by	Wrote the paper	Writing - Original Draft	YES
6373093	30755234	KB	4	data were collected by|data were analyzed by|data interpretation were done by|and manuscript preparation was undertaken by	data were collected by	Performed the experiments	Investigation	YES
6373093	30755234	KB	4	data were collected by|data were analyzed by|data interpretation were done by|and manuscript preparation was undertaken by	data were analyzed by	Analyzed the data	Formal analysis	YES
6373093	30755234	KB	4	data were collected by|data were analyzed by|data interpretation were done by|and manuscript preparation was undertaken by	data interpretation were done by	Analyzed the data	Formal analysis	YES
6373093	30755234	KB	4	data were collected by|data were analyzed by|data interpretation were done by|and manuscript preparation was undertaken by	and manuscript preparation was undertaken by	Wrote the paper	Writing - Original Draft	YES
6373093	30755234	LM	4	and manuscript preparation was undertaken by	and manuscript preparation was undertaken by	Wrote the paper	Writing - Original Draft	YES
5797782	29445383	All authors	PLoS52	agree to be accountable for the final manuscript	agree to be accountable for the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5797782	29445383	HM	PLoS52	designed the study|collected the materials|analyzed and interpreted the data|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5797782	29445383	HM	PLoS52	designed the study|collected the materials|analyzed and interpreted the data|wrote the manuscript	collected the materials	Performed the experiments	Investigation	YES
5797782	29445383	HM	PLoS52	designed the study|collected the materials|analyzed and interpreted the data|wrote the manuscript	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5797782	29445383	HM	PLoS52	designed the study|collected the materials|analyzed and interpreted the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5797782	29445383	LF	PLoS52	collected the materials|performed the experiments|analyzed and interpreted the data	collected the materials	Performed the experiments	Investigation	YES
5797782	29445383	LF	PLoS52	collected the materials|performed the experiments|analyzed and interpreted the data	performed the experiments	Performed the experiments	Investigation	YES
5797782	29445383	LF	PLoS52	collected the materials|performed the experiments|analyzed and interpreted the data	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5797782	29445383	TL	PLoS52	performed the experiments|analyzed and interpreted the data|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5797782	29445383	TL	PLoS52	performed the experiments|analyzed and interpreted the data|wrote the manuscript	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5797782	29445383	TL	PLoS52	performed the experiments|analyzed and interpreted the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5797782	29445383	XFL	PLoS52	analyzed and interpreted the data|wrote the manuscript	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5797782	29445383	XFL	PLoS52	analyzed and interpreted the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5797782	29445383	XXL	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5797782	29445383	YW	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5797782	29445383	ZL	PLoS52	collected the materials	collected the materials	Performed the experiments	Investigation	YES
4416765	25933432	BJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416765	25933432	BJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416765	25933432	BJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416765	25933432	BJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416765	25933432	BPP	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416765	25933432	GC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416765	25933432	GC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416765	25933432	GC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416765	25933432	JL	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416765	25933432	JMK	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416765	25933432	SL	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416765	25933432	SL	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416765	25933432	YHX	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1959119	17786203	BD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1959119	17786203	BD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1959119	17786203	BD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1959119	17786203	BD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1959119	17786203	KE	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1959119	17786203	MH	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1959119	17786203	NG	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1959119	17786203	RT	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1959119	17786203	SJ	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1959119	17786203	SR	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4780525	26926273	All authors	2	wrote the paper, revised the paper and gave final approval for publication	wrote the paper, revised the paper and gave final approval for publication	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5544660	28789482	AAS	PLoS52	made a substantial contribution to the analysis and interpretation of the data presented	made a substantial contribution to the analysis and interpretation of the data presented	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5544660	28789482	AE	PLoS52	made a substantial contribution to the analysis and interpretation of the data presented|made a substantial contribution to the analysis and interpretation of the data presented	made a substantial contribution to the analysis and interpretation of the data presented	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5544660	28789482	AE	PLoS52	made a substantial contribution to the analysis and interpretation of the data presented|made a substantial contribution to the analysis and interpretation of the data presented	made a substantial contribution to the analysis and interpretation of the data presented	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5544660	28789482	AT	PLoS52	performed the experiments|conceived and designed the experiments|wrote the paper|conceived and designed the experiments|performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5544660	28789482	AT	PLoS52	performed the experiments|conceived and designed the experiments|wrote the paper|conceived and designed the experiments|performed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5544660	28789482	AT	PLoS52	performed the experiments|conceived and designed the experiments|wrote the paper|conceived and designed the experiments|performed the experiments	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5544660	28789482	AT	PLoS52	performed the experiments|conceived and designed the experiments|wrote the paper|conceived and designed the experiments|performed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5544660	28789482	AT	PLoS52	performed the experiments|conceived and designed the experiments|wrote the paper|conceived and designed the experiments|performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5544660	28789482	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5544660	28789482	MA	PLoS52	made a substantial contribution to the analysis and interpretation of the data presented|made a substantial contribution to the analysis and interpretation of the data presented	made a substantial contribution to the analysis and interpretation of the data presented	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5544660	28789482	MA	PLoS52	made a substantial contribution to the analysis and interpretation of the data presented|made a substantial contribution to the analysis and interpretation of the data presented	made a substantial contribution to the analysis and interpretation of the data presented	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5544660	28789482	MHE	PLoS52	wrote the paper|conceived and designed the experiments	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5544660	28789482	MHE	PLoS52	wrote the paper|conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5544660	28789482	MM	PLoS52	performed the experiments|conceived and designed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5544660	28789482	MM	PLoS52	performed the experiments|conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5544660	28789482	MT	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5544660	28789482	MTG	PLoS52	performed the experiments|conceived and designed the experiments|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5544660	28789482	MTG	PLoS52	performed the experiments|conceived and designed the experiments|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5544660	28789482	MTG	PLoS52	performed the experiments|conceived and designed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5544660	28789482	The authors	PLoS52	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5544660	28789482	Zahedan Ariashimi Co	PLoS52	iran university of medical science for providing the technical, experimental materials, synthesis of nanoparticle and analysis of samples	iran university of medical science for providing the technical, experimental materials, synthesis of nanoparticle and analysis of samples	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
6270679	24786688	A.C.M.	PLoS5	Contributed to the antimicrobial and antioxidant experiments|Analyzed the data	Contributed to the antimicrobial and antioxidant experiments	Performed the experiments	Investigation	YES
6270679	24786688	A.C.M.	PLoS5	Contributed to the antimicrobial and antioxidant experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
6270679	24786688	B.S.	PLoS5	Contributed to the antimicrobial and antioxidant experiments	Contributed to the antimicrobial and antioxidant experiments	Performed the experiments	Investigation	YES
6270679	24786688	D.B.	PLoS5	Substantial contributions to conception and also to preparing the manuscript|Participated to phytochemical investigations|Contributed to the antimicrobial and antioxidant experiments|Analyzed the data	Substantial contributions to conception and also to preparing the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
6270679	24786688	D.B.	PLoS5	Substantial contributions to conception and also to preparing the manuscript|Participated to phytochemical investigations|Contributed to the antimicrobial and antioxidant experiments|Analyzed the data	Participated to phytochemical investigations	Performed the experiments	Investigation	YES
6270679	24786688	D.B.	PLoS5	Substantial contributions to conception and also to preparing the manuscript|Participated to phytochemical investigations|Contributed to the antimicrobial and antioxidant experiments|Analyzed the data	Contributed to the antimicrobial and antioxidant experiments	Performed the experiments	Investigation	YES
6270679	24786688	D.B.	PLoS5	Substantial contributions to conception and also to preparing the manuscript|Participated to phytochemical investigations|Contributed to the antimicrobial and antioxidant experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
6270679	24786688	D.H.	PLoS5	Contributed to the antimicrobial and antioxidant experiments	Contributed to the antimicrobial and antioxidant experiments	Performed the experiments	Investigation	YES
6270679	24786688	G.D.	PLoS5	Contributed to the antimicrobial and antioxidant experiments	Contributed to the antimicrobial and antioxidant experiments	Performed the experiments	Investigation	YES
6270679	24786688	I.C.	PLoS5	Contributed to the antimicrobial and antioxidant experiments	Contributed to the antimicrobial and antioxidant experiments	Performed the experiments	Investigation	YES
6270679	24786688	I.T.	PLoS5	Substantial contributions to conception and also to preparing the manuscript|Contributed to the antimicrobial and antioxidant experiments	Substantial contributions to conception and also to preparing the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
6270679	24786688	I.T.	PLoS5	Substantial contributions to conception and also to preparing the manuscript|Contributed to the antimicrobial and antioxidant experiments	Contributed to the antimicrobial and antioxidant experiments	Performed the experiments	Investigation	YES
6270679	24786688	L.V.	PLoS5	Substantial contributions to conception and also to preparing the manuscript|Participated to phytochemical investigations|Analyzed the data	Substantial contributions to conception and also to preparing the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
6270679	24786688	L.V.	PLoS5	Substantial contributions to conception and also to preparing the manuscript|Participated to phytochemical investigations|Analyzed the data	Participated to phytochemical investigations	Performed the experiments	Investigation	YES
6270679	24786688	L.V.	PLoS5	Substantial contributions to conception and also to preparing the manuscript|Participated to phytochemical investigations|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
6270679	24786688	R.S.-D.	PLoS5	Contributed to the antimicrobial and antioxidant experiments|Analyzed the data	Contributed to the antimicrobial and antioxidant experiments	Performed the experiments	Investigation	YES
6270679	24786688	R.S.-D.	PLoS5	Contributed to the antimicrobial and antioxidant experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5735924	29254503	FP	2	conceived the experiment, analyzed the results and wrote the paper	conceived the experiment, analyzed the results and wrote the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
5735924	29254503	N.D.	2	conceived the experiment, reared the fish, performed the experiments, analyzed the data and wrote the manuscript	conceived the experiment, reared the fish, performed the experiments, analyzed the data and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
5920239	29581097	HDU	2	conceived the study|wrote the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5920239	29581097	HDU	2	conceived the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5920239	29581097	MM	2	conceived the study|performed and analyzed experiments	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5920239	29581097	MM	2	conceived the study|performed and analyzed experiments	performed and analyzed experiments	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5920239	29581097	NG-R	2	conceived the study|performed and analyzed experiments|wrote the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5920239	29581097	NG-R	2	conceived the study|performed and analyzed experiments|wrote the manuscript	performed and analyzed experiments	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5920239	29581097	NG-R	2	conceived the study|performed and analyzed experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5920239	29581097	RPW	2	performed and analyzed experiments	performed and analyzed experiments	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5920239	29581097	YD	2	conceived the study|performed and analyzed experiments	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5920239	29581097	YD	2	conceived the study|performed and analyzed experiments	performed and analyzed experiments	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5920239	29581097	all authors	2	discussed the data and commented on the manuscript	discussed the data and commented on the manuscript	-	-	NO
5797785	29445385	AG	2	designed the research|conducted the research|collected and analyzed the data|wrote the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
5797785	29445385	AG	2	designed the research|conducted the research|collected and analyzed the data|wrote the manuscript	conducted the research	Performed the experiments	Investigation	YES
5797785	29445385	AG	2	designed the research|conducted the research|collected and analyzed the data|wrote the manuscript	collected and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5797785	29445385	AG	2	designed the research|conducted the research|collected and analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5797785	29445385	CE	2	designed the research|conducted the research	designed the research	Conceived and designed the experiments	Methodology	YES
5797785	29445385	CE	2	designed the research|conducted the research	conducted the research	Performed the experiments	Investigation	YES
5797785	29445385	CS	2	conducted the research|wrote the manuscript	conducted the research	Performed the experiments	Investigation	YES
5797785	29445385	CS	2	conducted the research|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5797785	29445385	GG	2	conducted the research|collected and analyzed the data|wrote the manuscript	conducted the research	Performed the experiments	Investigation	YES
5797785	29445385	GG	2	conducted the research|collected and analyzed the data|wrote the manuscript	collected and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5797785	29445385	GG	2	conducted the research|collected and analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5797785	29445385	JW	2	designed the research|wrote the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
5797785	29445385	JW	2	designed the research|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4416766	25932953	ABG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416766	25932953	AF	PLoS5	Electron microscopy	Electron microscopy	Performed the experiments	Investigation	YES
4416766	25932953	BY	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416766	25932953	EAP	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416766	25932953	JG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416766	25932953	JK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416766	25932953	JN	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416766	25932953	JN	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416766	25932953	KS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416766	25932953	LFD	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416766	25932953	MB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416766	25932953	MSm	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416766	25932953	MSo	PLoS5	Electron microscopy	Electron microscopy	Performed the experiments	Investigation	YES
4416766	25932953	MStan	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416766	25932953	MStap	PLoS5	Interpretation of stemness data	Interpretation of stemness data	Analyzed the data	Formal analysis	YES
4416766	25932953	MT	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416766	25932953	PH	PLoS5	Electron microscopy	Electron microscopy	Performed the experiments	Investigation	YES
4416766	25932953	RZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1959120	17848996	CP	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1959120	17848996	CP	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1959120	17848996	GS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1959120	17848996	GS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1959120	17848996	SM	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1959120	17848996	SM	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
6377763	30770758	AG	4	data interpretation and manuscript preparation were undertaken by	data interpretation and manuscript preparation were undertaken by	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6377763	30770758	AJ	4	The present study was designed by|data interpretation and manuscript preparation were undertaken by	The present study was designed by	Conceived and designed the experiments	Methodology	YES
6377763	30770758	AJ	4	The present study was designed by|data interpretation and manuscript preparation were undertaken by	data interpretation and manuscript preparation were undertaken by	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6377763	30770758	ASS	4	The present study was designed by|data interpretation and manuscript preparation were undertaken by	The present study was designed by	Conceived and designed the experiments	Methodology	YES
6377763	30770758	ASS	4	The present study was designed by|data interpretation and manuscript preparation were undertaken by	data interpretation and manuscript preparation were undertaken by	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6377763	30770758	BM	4	data interpretation and manuscript preparation were undertaken by	data interpretation and manuscript preparation were undertaken by	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6377763	30770758	EP	4	data interpretation and manuscript preparation were undertaken by	data interpretation and manuscript preparation were undertaken by	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6377763	30770758	JT	4	data were collected by	data were collected by	Performed the experiments	Investigation	YES
6377763	30770758	PB	4	data were collected by	data were collected by	Performed the experiments	Investigation	YES
5545993	28789484	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5545993	28789484	BC	2	helped to determine the samples	helped to determine the samples	-	-	NO
5545993	28789484	HY	2	provided important intellectual content in the research design	provided important intellectual content in the research design	Conceived and designed the experiments	-	YES
5545993	28789484	QR	2	helped to determine the samples	helped to determine the samples	-	-	NO
5545993	28789484	RL	2	provided important intellectual content in the research design	provided important intellectual content in the research design	Conceived and designed the experiments	-	YES
5545993	28789484	TW	2	helped to perform statistical analysis	helped to perform statistical analysis	Analyzed the data	Formal analysis	YES
5545993	28789484	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5545993	28789484	YW	2	conceived and performed the project, and drafted the manuscript	conceived and performed the project, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
5545993	28789484	ZW	2	contributed to research design and sample analysis	contributed to research design and sample analysis	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5797791	29445386	All authors	2	listed have made a substantial, direct and intellectual contribution to the work, and approved it for publication	listed have made a substantial, direct and intellectual contribution to the work, and approved it for publication	-	-	NO
5735938	29258441	HBW	2	conceived this study|collected data and data analyses|carried out experiments|wrote the manuscript with	conceived this study	Conceived and designed the experiments	Conceptualization	YES
5735938	29258441	HBW	2	conceived this study|collected data and data analyses|carried out experiments|wrote the manuscript with	collected data and data analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5735938	29258441	HBW	2	conceived this study|collected data and data analyses|carried out experiments|wrote the manuscript with	carried out experiments	Performed the experiments	Investigation	YES
5735938	29258441	HBW	2	conceived this study|collected data and data analyses|carried out experiments|wrote the manuscript with	wrote the manuscript with	Wrote the paper	Writing - Original Draft	YES
5735938	29258441	HS	2	collected data and data analyses	collected data and data analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5735938	29258441	RQL	2	carried out experiments	carried out experiments	Performed the experiments	Investigation	YES
5735938	29258441	XPD	2	carried out experiments	carried out experiments	Performed the experiments	Investigation	YES
5735938	29258441	XTL	2	contributed analysis tools	contributed analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5735938	29258441	YCL	2	conceived this study|collected data and data analyses|contributed analysis tools|carried out experiments|wrote the manuscript with	conceived this study	Conceived and designed the experiments	Conceptualization	YES
5735938	29258441	YCL	2	conceived this study|collected data and data analyses|contributed analysis tools|carried out experiments|wrote the manuscript with	collected data and data analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5735938	29258441	YCL	2	conceived this study|collected data and data analyses|contributed analysis tools|carried out experiments|wrote the manuscript with	contributed analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5735938	29258441	YCL	2	conceived this study|collected data and data analyses|contributed analysis tools|carried out experiments|wrote the manuscript with	carried out experiments	Performed the experiments	Investigation	YES
5735938	29258441	YCL	2	conceived this study|collected data and data analyses|contributed analysis tools|carried out experiments|wrote the manuscript with	wrote the manuscript with	Wrote the paper	Writing - Original Draft	YES
5735938	29258441	YSX	2	conceived this study	conceived this study	Conceived and designed the experiments	Conceptualization	YES
5735938	29258441	YYZ	2	collected data and data analyses	collected data and data analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5735938	29258441	all the authors	2	helped with the wrote the manuscript with	helped with the wrote the manuscript with	Wrote the paper	Writing - Original Draft	YES
5978319	29650682	FU	2	wrote the manuscript with input from all coauthors	wrote the manuscript with input from all coauthors	Wrote the paper	Writing - Original Draft	YES
5978319	29650682	SAT	2	wrote the manuscript with input from all coauthors	wrote the manuscript with input from all coauthors	Wrote the paper	Writing - Original Draft	YES
6270680	24972274	I. Baek	2	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
6270680	24972274	K. Hong	2	designed research and wrote the paper	designed research and wrote the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
6270680	24972274	M. Park	2	performed research	performed research	Performed the experiments	Investigation	YES
4416767	25933219	AN	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416767	25933219	AN	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416767	25933219	AN	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416767	25933219	DR	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416767	25933219	FE	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416767	25933219	GG	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416767	25933219	GG	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416767	25933219	JW	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416767	25933219	LK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416767	25933219	LK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4416767	25933219	LK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416767	25933219	PS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416767	25933219	PS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416767	25933219	PS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416767	25933219	PS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416767	25933219	SF	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416767	25933219	TR	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
3881687	24453853	Tiantian Mao	2	contributed equally to this study	contributed equally to this study	-	-	NO
3881687	24453853	Wenting Pan	2	contributed equally to this study	contributed equally to this study	-	-	NO
4780532	26926280	All authors	2	contributed to the overall design and interpretation	contributed to the overall design and interpretation	Conceived and designed the experiments|Analyzed the data	Formal analysis	YES
4780532	26926280	S.R.B.	2	with all authors involved in revising drafts	with all authors involved in revising drafts	Wrote the paper	Writing - Original Draft	YES
6379960	30777094	AM	2	performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
6379960	30777094	AZ	2	wrote the discussion and conclusions	wrote the discussion and conclusions	Wrote the paper	Writing - Original Draft	YES
6379960	30777094	All authors	2	participated in data interpretation	participated in data interpretation	Analyzed the data	Formal analysis	YES
6379960	30777094	JC	2	wrote the discussion and conclusions	wrote the discussion and conclusions	Wrote the paper	Writing - Original Draft	YES
6379960	30777094	MK	2	participated in the concept and design of the study	participated in the concept and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6379960	30777094	MW	2	participated in the concept and design of the study|wrote the discussion and conclusions	participated in the concept and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6379960	30777094	MW	2	participated in the concept and design of the study|wrote the discussion and conclusions	wrote the discussion and conclusions	Wrote the paper	Writing - Original Draft	YES
6270682	25036153	D. Chen	2	was responsible for performing most of the experiment and analysis, and preparing the draft of the manuscript	was responsible for performing most of the experiment and analysis, and preparing the draft of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6270682	25036153	Z. Zhao	2	designed the experiments and provided critical advice on operation of the analytical equipment	designed the experiments and provided critical advice on operation of the analytical equipment	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources	YES
5738135	29262781	BS	2	devised such research and also revised manuscript for publishing	devised such research and also revised manuscript for publishing	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5738135	29262781	BSS	2	were responsible for the blood sample collection	were responsible for the blood sample collection	Performed the experiments	Investigation	YES
5738135	29262781	JFZ	2	devised such research and also revised manuscript for publishing	devised such research and also revised manuscript for publishing	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5738135	29262781	LKL	2	devised such research and also revised manuscript for publishing	devised such research and also revised manuscript for publishing	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5738135	29262781	QQW	2	advised on the biological functional experiment	advised on the biological functional experiment	-	-	NO
5738135	29262781	TZ	2	were responsible for the blood sample collection	were responsible for the blood sample collection	Performed the experiments	Investigation	YES
5738135	29262781	XYD	2	advised on the biological functional experiment	advised on the biological functional experiment	-	-	NO
5738135	29262781	XYH	2	advised on the biological functional experiment	advised on the biological functional experiment	-	-	NO
5738135	29262781	ZXY	2	performed the sequencing and statistical analyses and manuscript preparing	performed the sequencing and statistical analyses and manuscript preparing	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5548705	28791618	AAA	2	contributed in designing the work and helped in drafting the manuscript	contributed in designing the work and helped in drafting the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
5548705	28791618	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5548705	28791618	HZ	2	contributed in designing the work and helped in drafting the manuscript	contributed in designing the work and helped in drafting the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
5548705	28791618	LA	2	carried out the main experiments, participated in the review collection and drafted the manuscript	carried out the main experiments, participated in the review collection and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5548705	28791618	ML	2	carried out the main experiments, participated in the review collection and drafted the manuscript	carried out the main experiments, participated in the review collection and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5548705	28791618	NA	2	contributed in designing the work and helped in drafting the manuscript|participated in the design of the study, supervision of the research work, reviewing and editing the manuscript	contributed in designing the work and helped in drafting the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
5548705	28791618	NA	2	contributed in designing the work and helped in drafting the manuscript|participated in the design of the study, supervision of the research work, reviewing and editing the manuscript	participated in the design of the study, supervision of the research work, reviewing and editing the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Supervision|Writing - Review & Editing	YES
5797807	29445382	AB	2	conducted the morphological analysis	conducted the morphological analysis	Performed the experiments	Investigation	YES
5797807	29445382	AS	2	coordinated data collection and reviewed the manuscript	coordinated data collection and reviewed the manuscript	Performed the experiments|Wrote the paper	Investigation|Project administration|Writing - Review & Editing	YES
5797807	29445382	CB	2	wrote the main manuscript and performed the oa analysis	wrote the main manuscript and performed the oa analysis	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5797807	29445382	DP	2	conducted the morphological analysis	conducted the morphological analysis	Performed the experiments	Investigation	YES
5797807	29445382	GB	2	wrote the main manuscript and performed the oa analysis	wrote the main manuscript and performed the oa analysis	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5797807	29445382	GC	2	coordinated data collection and reviewed the manuscript	coordinated data collection and reviewed the manuscript	Performed the experiments|Wrote the paper	Investigation|Project administration|Writing - Review & Editing	YES
5797807	29445382	GM	2	developed the panel of taqman assays for the oa analysis	developed the panel of taqman assays for the oa analysis	Performed the experiments	Investigation	YES
5797807	29445382	LL	2	performed the metabolomic analysis	performed the metabolomic analysis	Performed the experiments	Investigation	YES
5797807	29445382	MB	2	conducted the ionomic analysis	conducted the ionomic analysis	Performed the experiments	Investigation	YES
5797807	29445382	MC	2	conducted the ionomic analysis	conducted the ionomic analysis	Performed the experiments	Investigation	YES
5797807	29445382	PS	2	wrote the main manuscript and performed the oa analysis	wrote the main manuscript and performed the oa analysis	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5797807	29445382	SN	2	coordinated data collection and reviewed the manuscript	coordinated data collection and reviewed the manuscript	Performed the experiments|Wrote the paper	Investigation|Project administration|Writing - Review & Editing	YES
5797807	29445382	VB	2	conducted the morphological analysis	conducted the morphological analysis	Performed the experiments	Investigation	YES
5797807	29445382	VM	2	developed the panel of taqman assays for the oa analysis	developed the panel of taqman assays for the oa analysis	Performed the experiments	Investigation	YES
4416768	25933435	FS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416768	25933435	FS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416768	25933435	FS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416768	25933435	FS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416768	25933435	MB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416768	25933435	MB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416768	25933435	MB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416768	25933435	RRR	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416768	25933435	RRR	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416768	25933435	RS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416768	25933435	RS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416768	25933435	RS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416768	25933435	SL	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416768	25933435	SL	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1959121	17848997	AP	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1959121	17848997	AP	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1959121	17848997	MM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1959121	17848997	NM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1959121	17848997	NM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1959121	17848997	NM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1959121	17848997	NT	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1959121	17848997	NT	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1959121	17848997	SH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5978322	29669860	AH	CRediT	Methodology|Investigation|Writing--review & editing	Methodology	Performed the experiments	Methodology	YES
5978322	29669860	AH	CRediT	Methodology|Investigation|Writing--review & editing	Investigation	Performed the experiments	Investigation	YES
5978322	29669860	AH	CRediT	Methodology|Investigation|Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
5978322	29669860	JP	CRediT	Methodology|Investigation|Writing--review & editing	Methodology	Performed the experiments	Methodology	YES
5978322	29669860	JP	CRediT	Methodology|Investigation|Writing--review & editing	Investigation	Performed the experiments	Investigation	YES
5978322	29669860	JP	CRediT	Methodology|Investigation|Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
5978322	29669860	MB	CRediT	Methodology|Investigation|Writing--original Draft|Writing--review & editing|Supervision	Methodology	Performed the experiments	Methodology	YES
5978322	29669860	MB	CRediT	Methodology|Investigation|Writing--original Draft|Writing--review & editing|Supervision	Investigation	Performed the experiments	Investigation	YES
5978322	29669860	MB	CRediT	Methodology|Investigation|Writing--original Draft|Writing--review & editing|Supervision	Writing--original Draft	Wrote the paper	Writing - Original Draft	YES
5978322	29669860	MB	CRediT	Methodology|Investigation|Writing--original Draft|Writing--review & editing|Supervision	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
5978322	29669860	MB	CRediT	Methodology|Investigation|Writing--original Draft|Writing--review & editing|Supervision	Supervision	-	Supervision	YES
5978322	29669860	MG	CRediT	Methodology	Methodology	Performed the experiments	Methodology	YES
5978322	29669860	MT	CRediT	Methodology|Writing--review & editing|Supervision	Methodology	Performed the experiments	Methodology	YES
5978322	29669860	MT	CRediT	Methodology|Writing--review & editing|Supervision	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
5978322	29669860	MT	CRediT	Methodology|Writing--review & editing|Supervision	Supervision	-	Supervision	YES
5978322	29669860	TPM	CRediT	Methodology|Investigation|Writing--review & editing	Methodology	Performed the experiments	Methodology	YES
5978322	29669860	TPM	CRediT	Methodology|Investigation|Writing--review & editing	Investigation	Performed the experiments	Investigation	YES
5978322	29669860	TPM	CRediT	Methodology|Investigation|Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
5978322	29669860	VMJ	CRediT	Methodology|Writing--review & editing	Methodology	Performed the experiments	Methodology	YES
5978322	29669860	VMJ	CRediT	Methodology|Writing--review & editing	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
4780537	26926285	All authors	2	contributed to the drafting of the manuscript|gave final approval for publication	contributed to the drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
4780537	26926285	All authors	2	contributed to the drafting of the manuscript|gave final approval for publication	gave final approval for publication	-	-	NO
6381705	30782172	GC	2	participated in the study design, collected data, interpreted the data, and wrote the article|participated in the study design, and wrote the manuscript	participated in the study design, collected data, interpreted the data, and wrote the article	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
6381705	30782172	GC	2	participated in the study design, collected data, interpreted the data, and wrote the article|participated in the study design, and wrote the manuscript	participated in the study design, and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
6381705	30782172	GDP	2	participated in the study design, and wrote the manuscript	participated in the study design, and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
6381705	30782172	JFM	2	participated in the study design, and wrote the manuscript	participated in the study design, and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
6381705	30782172	LG	2	participated in the study design, and wrote the manuscript	participated in the study design, and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
6381705	30782172	MB	2	participated in the study design, and wrote the manuscript	participated in the study design, and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
6381705	30782172	PG	2	participated in the study design, and wrote the manuscript	participated in the study design, and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5567572	28831762	All	2	authors read and approved the final manuscript	authors read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5567572	28831762	CL	2	conceived of the study|authors read and approved the final manuscript	conceived of the study	Conceived and designed the experiments	Conceptualization	YES
5567572	28831762	CL	2	conceived of the study|authors read and approved the final manuscript	authors read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5567572	28831762	MSMJ	2	authors read and approved the final manuscript	authors read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6270683	24566326	All the authors	2	had known about this manuscript and had no objection to submitting it	had known about this manuscript and had no objection to submitting it	-	-	NO
5797882	29445387	GJ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5797882	29445387	GhW	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5797882	29445387	GyW	PLoS52	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5797882	29445387	JF	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5797882	29445387	JW	PLoS52	designed the study|advised on data analysis and revised the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5797882	29445387	JW	PLoS52	designed the study|advised on data analysis and revised the manuscript	advised on data analysis and revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5797882	29445387	LL	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5797882	29445387	LR	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5797882	29445387	RG	PLoS52	designed the study|advised on data analysis and revised the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5797882	29445387	RG	PLoS52	designed the study|advised on data analysis and revised the manuscript	advised on data analysis and revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5797882	29445387	TL	PLoS52	advised on data analysis and revised the manuscript	advised on data analysis and revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5797882	29445387	XL	PLoS52	performed the experiments|analyzed the data|drafted the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5797882	29445387	XL	PLoS52	performed the experiments|analyzed the data|drafted the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5797882	29445387	XL	PLoS52	performed the experiments|analyzed the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4416769	25933346	AB	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416769	25933346	AB	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416769	25933346	ACL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416769	25933346	ACL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416769	25933346	ACL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416769	25933346	ADM	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416769	25933346	AG	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416769	25933346	AG	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416769	25933346	CM	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416769	25933346	FS	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416769	25933346	GM	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416769	25933346	PB	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416769	25933346	RL	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416769	25933346	SB	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5738166	29258423	GS	2	did the data analysis	did the data analysis	Analyzed the data	Formal analysis	YES
5738166	29258423	IAC	2	performed the strand-specific rna seq|did the data analysis|wrote the manuscript	performed the strand-specific rna seq	Performed the experiments	Investigation	YES
5738166	29258423	IAC	2	performed the strand-specific rna seq|did the data analysis|wrote the manuscript	did the data analysis	Analyzed the data	Formal analysis	YES
5738166	29258423	IAC	2	performed the strand-specific rna seq|did the data analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5738166	29258423	MB	2	wrote the manuscript|supervised the project	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5738166	29258423	MB	2	wrote the manuscript|supervised the project	supervised the project	-	Supervision	YES
5738166	29258423	NH	2	did the data analysis|developed the neutra website	did the data analysis	Analyzed the data	Formal analysis	YES
5738166	29258423	NH	2	did the data analysis|developed the neutra website	developed the neutra website	Contributed reagents/materials/analysis tools	Software	YES
5738166	29258423	SY	2	performed the polyribosome fractionation dataset	performed the polyribosome fractionation dataset	Performed the experiments	Investigation	YES
4810813	26977060	Both authors	2	gave final approval for publication	gave final approval for publication	-	-	NO
4810813	26977060	L.H.L.	2	gave final approval for publication	gave final approval for publication	-	-	NO
5978383	29661885	BS	2	designed and performed the experiments	designed and performed the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5978383	29661885	CPP	2	who reviewed and edited the drafts|supervised the research and acquired funding	who reviewed and edited the drafts	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5978383	29661885	CPP	2	who reviewed and edited the drafts|supervised the research and acquired funding	supervised the research and acquired funding	-	Funding acquisition|Supervision	YES
5978383	29661885	DJW	2	carried out computational analysis of the microarray and chip-seq data	carried out computational analysis of the microarray and chip-seq data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5978383	29661885	FA	2	designed and performed the experiments	designed and performed the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5978383	29661885	FGS	2	designed and performed the experiments|analysed and interpreted the data|supervised the research and acquired funding	designed and performed the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5978383	29661885	FGS	2	designed and performed the experiments|analysed and interpreted the data|supervised the research and acquired funding	analysed and interpreted the data	Analyzed the data	Formal analysis	YES
5978383	29661885	FGS	2	designed and performed the experiments|analysed and interpreted the data|supervised the research and acquired funding	supervised the research and acquired funding	-	Funding acquisition|Supervision	YES
5978383	29661885	IP	2	designed and performed the experiments|analysed and interpreted the data|who reviewed and edited the drafts	designed and performed the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5978383	29661885	IP	2	designed and performed the experiments|analysed and interpreted the data|who reviewed and edited the drafts	analysed and interpreted the data	Analyzed the data	Formal analysis	YES
5978383	29661885	IP	2	designed and performed the experiments|analysed and interpreted the data|who reviewed and edited the drafts	who reviewed and edited the drafts	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5978383	29661885	KWV	2	conceived the study|designed and performed the experiments|analysed and interpreted the data|supervised the research and acquired funding	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5978383	29661885	KWV	2	conceived the study|designed and performed the experiments|analysed and interpreted the data|supervised the research and acquired funding	designed and performed the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5978383	29661885	KWV	2	conceived the study|designed and performed the experiments|analysed and interpreted the data|supervised the research and acquired funding	analysed and interpreted the data	Analyzed the data	Formal analysis	YES
5978383	29661885	KWV	2	conceived the study|designed and performed the experiments|analysed and interpreted the data|supervised the research and acquired funding	supervised the research and acquired funding	-	Funding acquisition|Supervision	YES
5978383	29661885	NC	2	carried out computational analysis of the microarray and chip-seq data	carried out computational analysis of the microarray and chip-seq data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5978383	29661885	SL	2	designed and performed the experiments|carried out computational analysis of the microarray and chip-seq data	designed and performed the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5978383	29661885	SL	2	designed and performed the experiments|carried out computational analysis of the microarray and chip-seq data	carried out computational analysis of the microarray and chip-seq data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5978383	29661885	TS	2	designed and performed the experiments	designed and performed the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
1959122	17786226	CP	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1959122	17786226	CP	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1959122	17786226	CT	PLoS5	Conceived and designed the experiments|Wrote the paper|Performed the simulations	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1959122	17786226	CT	PLoS5	Conceived and designed the experiments|Wrote the paper|Performed the simulations	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1959122	17786226	CT	PLoS5	Conceived and designed the experiments|Wrote the paper|Performed the simulations	Performed the simulations	Performed the experiments	Formal analysis|Investigation	YES
1959122	17786226	DA	PLoS5	Wrote the paper|Provided biological knowledge	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1959122	17786226	DA	PLoS5	Wrote the paper|Provided biological knowledge	Provided biological knowledge	-	-	NO
1959122	17786226	MK	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1959122	17786226	MK	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6391781	30813949	AG	2	conceived and planned the study|conducted the search and were involved in the review and extraction of all data|performed the analysis on the extracted data|wrote the manuscript	conceived and planned the study	Conceived and designed the experiments	Conceptualization	YES
6391781	30813949	AG	2	conceived and planned the study|conducted the search and were involved in the review and extraction of all data|performed the analysis on the extracted data|wrote the manuscript	conducted the search and were involved in the review and extraction of all data	Performed the experiments	Investigation	YES
6391781	30813949	AG	2	conceived and planned the study|conducted the search and were involved in the review and extraction of all data|performed the analysis on the extracted data|wrote the manuscript	performed the analysis on the extracted data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6391781	30813949	AG	2	conceived and planned the study|conducted the search and were involved in the review and extraction of all data|performed the analysis on the extracted data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6391781	30813949	All authors	2	discussed the interpretation of results|provided critical feedback and helped shape the manuscript	discussed the interpretation of results	Analyzed the data	Formal analysis	YES
6391781	30813949	All authors	2	discussed the interpretation of results|provided critical feedback and helped shape the manuscript	provided critical feedback and helped shape the manuscript	-	-	NO
6391781	30813949	JM	2	conducted the search and were involved in the review and extraction of all data|performed the analysis on the extracted data	conducted the search and were involved in the review and extraction of all data	Performed the experiments	Investigation	YES
6391781	30813949	JM	2	conducted the search and were involved in the review and extraction of all data|performed the analysis on the extracted data	performed the analysis on the extracted data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6391781	30813949	JOH	2	conceived and planned the study	conceived and planned the study	Conceived and designed the experiments	Conceptualization	YES
6391781	30813949	KD	2	conceived and planned the study|conducted the search and were involved in the review and extraction of all data|performed the analysis on the extracted data	conceived and planned the study	Conceived and designed the experiments	Conceptualization	YES
6391781	30813949	KD	2	conceived and planned the study|conducted the search and were involved in the review and extraction of all data|performed the analysis on the extracted data	conducted the search and were involved in the review and extraction of all data	Performed the experiments	Investigation	YES
6391781	30813949	KD	2	conceived and planned the study|conducted the search and were involved in the review and extraction of all data|performed the analysis on the extracted data	performed the analysis on the extracted data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6391781	30813949	OS	2	conducted the search and were involved in the review and extraction of all data	conducted the search and were involved in the review and extraction of all data	Performed the experiments	Investigation	YES
6391781	30813949	RK	2	conceived and planned the study	conceived and planned the study	Conceived and designed the experiments	Conceptualization	YES
5797883	29445388	AT	PLoS5	Edited the manuscript and contributed to data analysis	Edited the manuscript and contributed to data analysis	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5797883	29445388	AvT	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5797883	29445388	BK	PLoS5	Contributed reagents/materials/analysis tools|Edited the manuscript and contributed to data analysis	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5797883	29445388	BK	PLoS5	Contributed reagents/materials/analysis tools|Edited the manuscript and contributed to data analysis	Edited the manuscript and contributed to data analysis	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5797883	29445388	CT	PLoS5	Conceived and designed the experiments|Performed the field experiments|Performed the glasshouse experiments and laboratory analysis|Analyzed the data|Drafted the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5797883	29445388	CT	PLoS5	Conceived and designed the experiments|Performed the field experiments|Performed the glasshouse experiments and laboratory analysis|Analyzed the data|Drafted the manuscript	Performed the field experiments	Performed the experiments	Investigation	YES
5797883	29445388	CT	PLoS5	Conceived and designed the experiments|Performed the field experiments|Performed the glasshouse experiments and laboratory analysis|Analyzed the data|Drafted the manuscript	Performed the glasshouse experiments and laboratory analysis	Performed the experiments	Investigation	YES
5797883	29445388	CT	PLoS5	Conceived and designed the experiments|Performed the field experiments|Performed the glasshouse experiments and laboratory analysis|Analyzed the data|Drafted the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
5797883	29445388	CT	PLoS5	Conceived and designed the experiments|Performed the field experiments|Performed the glasshouse experiments and laboratory analysis|Analyzed the data|Drafted the manuscript	Drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5797883	29445388	EA	PLoS5	Conceived and designed the experiments|Performed the field experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Drafted the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5797883	29445388	EA	PLoS5	Conceived and designed the experiments|Performed the field experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Drafted the manuscript	Performed the field experiments	Performed the experiments	Investigation	YES
5797883	29445388	EA	PLoS5	Conceived and designed the experiments|Performed the field experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Drafted the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
5797883	29445388	EA	PLoS5	Conceived and designed the experiments|Performed the field experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Drafted the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5797883	29445388	EA	PLoS5	Conceived and designed the experiments|Performed the field experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Drafted the manuscript	Drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5797883	29445388	FL-E	PLoS5	Conceived and designed the experiments|Performed the field experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Drafted the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5797883	29445388	FL-E	PLoS5	Conceived and designed the experiments|Performed the field experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Drafted the manuscript	Performed the field experiments	Performed the experiments	Investigation	YES
5797883	29445388	FL-E	PLoS5	Conceived and designed the experiments|Performed the field experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Drafted the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
5797883	29445388	FL-E	PLoS5	Conceived and designed the experiments|Performed the field experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Drafted the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5797883	29445388	FL-E	PLoS5	Conceived and designed the experiments|Performed the field experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Drafted the manuscript	Drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5797883	29445388	JJ	PLoS5	Performed the field experiments|Performed the glasshouse experiments and laboratory analysis|Analyzed the data	Performed the field experiments	Performed the experiments	Investigation	YES
5797883	29445388	JJ	PLoS5	Performed the field experiments|Performed the glasshouse experiments and laboratory analysis|Analyzed the data	Performed the glasshouse experiments and laboratory analysis	Performed the experiments	Investigation	YES
5797883	29445388	JJ	PLoS5	Performed the field experiments|Performed the glasshouse experiments and laboratory analysis|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5797883	29445388	JR	PLoS5	Performed the glasshouse experiments and laboratory analysis|Edited the manuscript and contributed to data analysis	Performed the glasshouse experiments and laboratory analysis	Performed the experiments	Investigation	YES
5797883	29445388	JR	PLoS5	Performed the glasshouse experiments and laboratory analysis|Edited the manuscript and contributed to data analysis	Edited the manuscript and contributed to data analysis	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5797883	29445388	MA-V	PLoS5	Performed the glasshouse experiments and laboratory analysis	Performed the glasshouse experiments and laboratory analysis	Performed the experiments	Investigation	YES
5797883	29445388	MP-R	PLoS5	Performed the field experiments|Performed the glasshouse experiments and laboratory analysis	Performed the field experiments	Performed the experiments	Investigation	YES
5797883	29445388	MP-R	PLoS5	Performed the field experiments|Performed the glasshouse experiments and laboratory analysis	Performed the glasshouse experiments and laboratory analysis	Performed the experiments	Investigation	YES
5797883	29445388	PK	PLoS5	Edited the manuscript and contributed to data analysis	Edited the manuscript and contributed to data analysis	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5567573	28831735	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5567573	28831735	Bruce Boschek	2	in drafting of the manuscript is gratefully acknowledged	in drafting of the manuscript is gratefully acknowledged	Wrote the paper	Writing - Original Draft	YES
5567573	28831735	HZ	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5567573	28831735	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
6270684	25255754	BH	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270684	25255754	HL	PLoS52	designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
6270684	25255754	JEJ	PLoS52	designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
6270684	25255754	MK	PLoS52	designed the research|wrote the paper	designed the research	Conceived and designed the experiments	Methodology	YES
6270684	25255754	MK	PLoS52	designed the research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6396487	30819184	All	2	authors contributed to the data collection and entry	authors contributed to the data collection and entry	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
6396487	30819184	JAP	2	authors contributed to the data collection and entry	authors contributed to the data collection and entry	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
6396487	30819184	KAE	2	authors contributed to the data collection and entry	authors contributed to the data collection and entry	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
6396487	30819184	KWJ	2	authors contributed to the data collection and entry	authors contributed to the data collection and entry	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5797932	29445390	CP	3	All authors wrote different sections of the mini-review, and the completed manuscript was assembled and edited by the corresponding author	All authors wrote different sections of the mini-review, and the completed manuscript was assembled and edited by the corresponding author	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
1959184	17786216	AH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1959184	17786216	AH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1959184	17786216	AH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1959184	17786216	AH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1959184	17786216	EG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1959184	17786216	EG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1959184	17786216	EG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1959184	17786216	EG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1959184	17786216	IM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1959184	17786216	IM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1959184	17786216	IM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1959184	17786216	IM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1959184	17786216	IM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1959184	17786216	ND	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1959184	17786216	ND	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1959184	17786216	RA	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1959184	17786216	SA	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1959184	17786216	SM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5567576	28831757	All authors	2	read and approved the final manuscript|gave the consented for publication	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5567576	28831757	All authors	2	read and approved the final manuscript|gave the consented for publication	gave the consented for publication	-	-	NO
5567576	28831757	HA	2	designed the research|supervised the research|analysed data|wrote the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
5567576	28831757	HA	2	designed the research|supervised the research|analysed data|wrote the manuscript	supervised the research	-	Supervision	YES
5567576	28831757	HA	2	designed the research|supervised the research|analysed data|wrote the manuscript	analysed data	Analyzed the data	Formal analysis	YES
5567576	28831757	HA	2	designed the research|supervised the research|analysed data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5567576	28831757	MT	2	designed the research|created the cdmss|performed all culture experiment|analysed data|wrote the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
5567576	28831757	MT	2	designed the research|created the cdmss|performed all culture experiment|analysed data|wrote the manuscript	created the cdmss	-	-	NO
5567576	28831757	MT	2	designed the research|created the cdmss|performed all culture experiment|analysed data|wrote the manuscript	performed all culture experiment	Performed the experiments	Investigation	YES
5567576	28831757	MT	2	designed the research|created the cdmss|performed all culture experiment|analysed data|wrote the manuscript	analysed data	Analyzed the data	Formal analysis	YES
5567576	28831757	MT	2	designed the research|created the cdmss|performed all culture experiment|analysed data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5567576	28831757	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5567576	28831757	YS	2	created the cdmss	created the cdmss	-	-	NO
4416770	25933413	HA	PLoS5	Conceived and designed the experiments|Wrote the paper|Obtained access and provided information about the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416770	25933413	HA	PLoS5	Conceived and designed the experiments|Wrote the paper|Obtained access and provided information about the data	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416770	25933413	HA	PLoS5	Conceived and designed the experiments|Wrote the paper|Obtained access and provided information about the data	Obtained access and provided information about the data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4416770	25933413	HI	PLoS5	Conceived and designed the experiments|Wrote the paper|Obtained access and provided information about the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416770	25933413	HI	PLoS5	Conceived and designed the experiments|Wrote the paper|Obtained access and provided information about the data	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416770	25933413	HI	PLoS5	Conceived and designed the experiments|Wrote the paper|Obtained access and provided information about the data	Obtained access and provided information about the data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4416770	25933413	LM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416770	25933413	LM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416770	25933413	LM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416770	25933413	LM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416770	25933413	MG	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416770	25933413	MG	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416770	25933413	RNM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416770	25933413	RNM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416770	25933413	RNM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416770	25933413	RNM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416770	25933413	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416770	25933413	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416770	25933413	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416770	25933413	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416770	25933413	YF	PLoS5	Conceived and designed the experiments|Wrote the paper|Obtained access and provided information about the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416770	25933413	YF	PLoS5	Conceived and designed the experiments|Wrote the paper|Obtained access and provided information about the data	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416770	25933413	YF	PLoS5	Conceived and designed the experiments|Wrote the paper|Obtained access and provided information about the data	Obtained access and provided information about the data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4810815	26977062	All authors	2	made substantial contributions to both designing the study and producing the final manuscript	made substantial contributions to both designing the study and producing the final manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
4810815	26977062	J.R.	2	designed the study|assisted with the wrote the software with advice and|derived the analytical results|made substantial contributions to both designing the study and producing the final manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
4810815	26977062	J.R.	2	designed the study|assisted with the wrote the software with advice and|derived the analytical results|made substantial contributions to both designing the study and producing the final manuscript	assisted with the wrote the software with advice and	Contributed reagents/materials/analysis tools|Wrote the paper	Software|Writing - Original Draft	YES
4810815	26977062	J.R.	2	designed the study|assisted with the wrote the software with advice and|derived the analytical results|made substantial contributions to both designing the study and producing the final manuscript	derived the analytical results	Analyzed the data	Formal analysis	YES
4810815	26977062	J.R.	2	designed the study|assisted with the wrote the software with advice and|derived the analytical results|made substantial contributions to both designing the study and producing the final manuscript	made substantial contributions to both designing the study and producing the final manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
4810815	26977062	S.J.	2	designed the study|wrote the software with advice and	designed the study	Conceived and designed the experiments	Methodology	YES
4810815	26977062	S.J.	2	designed the study|wrote the software with advice and	wrote the software with advice and	Contributed reagents/materials/analysis tools|Wrote the paper	Software|Writing - Original Draft	YES
4810815	26977062	T.B.	2	designed the study|made substantial contributions to both designing the study and producing the final manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
4810815	26977062	T.B.	2	designed the study|made substantial contributions to both designing the study and producing the final manuscript	made substantial contributions to both designing the study and producing the final manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5978567	29650680	ASp	2	performed the western blot investigations	performed the western blot investigations	Performed the experiments	Investigation	YES
5978567	29650680	ASt	2	performed the qrt-pcr analysis	performed the qrt-pcr analysis	Performed the experiments	Investigation	YES
5978567	29650680	AW	2	performed immunofluorescence studies with subsequent intensity quantifications, cilia length measurements and statistics|measured defect frequencies|performed the transmission electron microscopic studies|prepared figures|assisted with the wrote the manuscript with	performed immunofluorescence studies with subsequent intensity quantifications, cilia length measurements and statistics	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5978567	29650680	AW	2	performed immunofluorescence studies with subsequent intensity quantifications, cilia length measurements and statistics|measured defect frequencies|performed the transmission electron microscopic studies|prepared figures|assisted with the wrote the manuscript with	measured defect frequencies	Performed the experiments	Investigation	YES
5978567	29650680	AW	2	performed immunofluorescence studies with subsequent intensity quantifications, cilia length measurements and statistics|measured defect frequencies|performed the transmission electron microscopic studies|prepared figures|assisted with the wrote the manuscript with	performed the transmission electron microscopic studies	Performed the experiments	Investigation	YES
5978567	29650680	AW	2	performed immunofluorescence studies with subsequent intensity quantifications, cilia length measurements and statistics|measured defect frequencies|performed the transmission electron microscopic studies|prepared figures|assisted with the wrote the manuscript with	prepared figures	-	Visualization	YES
5978567	29650680	AW	2	performed immunofluorescence studies with subsequent intensity quantifications, cilia length measurements and statistics|measured defect frequencies|performed the transmission electron microscopic studies|prepared figures|assisted with the wrote the manuscript with	assisted with the wrote the manuscript with	Wrote the paper	Writing - Original Draft	YES
5978567	29650680	All authors	2	approved the manuscript	approved the manuscript	-	-	NO
5978567	29650680	CG	2	conceived the study and designed experiments|performed the western blot investigations|performed fluorescence intensity quantifications of 3d reconstructed images obtained by using 3d-sim|wrote the manuscript with	conceived the study and designed experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5978567	29650680	CG	2	conceived the study and designed experiments|performed the western blot investigations|performed fluorescence intensity quantifications of 3d reconstructed images obtained by using 3d-sim|wrote the manuscript with	performed the western blot investigations	Performed the experiments	Investigation	YES
5978567	29650680	CG	2	conceived the study and designed experiments|performed the western blot investigations|performed fluorescence intensity quantifications of 3d reconstructed images obtained by using 3d-sim|wrote the manuscript with	performed fluorescence intensity quantifications of 3d reconstructed images obtained by using 3d-sim	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
5978567	29650680	CG	2	conceived the study and designed experiments|performed the western blot investigations|performed fluorescence intensity quantifications of 3d reconstructed images obtained by using 3d-sim|wrote the manuscript with	wrote the manuscript with	Wrote the paper	Writing - Original Draft	YES
5978567	29650680	JML	2	performed immunofluorescence studies with subsequent intensity quantifications, cilia length measurements and statistics	performed immunofluorescence studies with subsequent intensity quantifications, cilia length measurements and statistics	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5978567	29650680	LK	2	performed immunofluorescence studies with subsequent intensity quantifications, cilia length measurements and statistics|inactivated several genes in different cells via the crispr/cas9 system	performed immunofluorescence studies with subsequent intensity quantifications, cilia length measurements and statistics	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5978567	29650680	LK	2	performed immunofluorescence studies with subsequent intensity quantifications, cilia length measurements and statistics|inactivated several genes in different cells via the crispr/cas9 system	inactivated several genes in different cells via the crispr/cas9 system	Performed the experiments	Investigation	YES
5978567	29650680	RD	2	inactivated several genes in different cells via the crispr/cas9 system|performed phylogenetic and evolutionary studies|prepared figures	inactivated several genes in different cells via the crispr/cas9 system	Performed the experiments	Investigation	YES
5978567	29650680	RD	2	inactivated several genes in different cells via the crispr/cas9 system|performed phylogenetic and evolutionary studies|prepared figures	performed phylogenetic and evolutionary studies	Performed the experiments	Investigation	YES
5978567	29650680	RD	2	inactivated several genes in different cells via the crispr/cas9 system|performed phylogenetic and evolutionary studies|prepared figures	prepared figures	-	Visualization	YES
5978567	29650680	SD	2	inactivated several genes in different cells via the crispr/cas9 system	inactivated several genes in different cells via the crispr/cas9 system	Performed the experiments	Investigation	YES
5978567	29650680	SK	2	performed immunofluorescence studies with subsequent intensity quantifications, cilia length measurements and statistics|performed the western blot investigations	performed immunofluorescence studies with subsequent intensity quantifications, cilia length measurements and statistics	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5978567	29650680	SK	2	performed immunofluorescence studies with subsequent intensity quantifications, cilia length measurements and statistics|performed the western blot investigations	performed the western blot investigations	Performed the experiments	Investigation	YES
5978567	29650680	TL	2	performed immunofluorescence studies with subsequent intensity quantifications, cilia length measurements and statistics	performed immunofluorescence studies with subsequent intensity quantifications, cilia length measurements and statistics	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5978567	29650680	TZ	2	performed fluorescence intensity quantifications of 3d reconstructed images obtained by using 3d-sim	performed fluorescence intensity quantifications of 3d reconstructed images obtained by using 3d-sim	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
5978567	29650680	UR	2	assisted with the wrote the manuscript with|obtained funding for the study	assisted with the wrote the manuscript with	Wrote the paper	Writing - Original Draft	YES
5978567	29650680	UR	2	assisted with the wrote the manuscript with|obtained funding for the study	obtained funding for the study	-	Funding acquisition	YES
5738175	29258434	FC	2	participated in experiments and analyzed the data	participated in experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5738175	29258434	HW	2	participated in experiments and analyzed the data	participated in experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5738175	29258434	HY	2	participated in experiments and analyzed the data	participated in experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5738175	29258434	JS	2	participated in experiments and analyzed the data	participated in experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5738175	29258434	JW	2	designed and performed experiments, analyzed the data and wrote the manuscript	designed and performed experiments, analyzed the data and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5738175	29258434	MD	2	participated in experiments and analyzed the data	participated in experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5738175	29258434	XC	2	participated in experiments and analyzed the data	participated in experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5738175	29258434	XL	2	conceived the project and revised the manuscript	conceived the project and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5738175	29258434	XZ	2	participated in experiments and analyzed the data	participated in experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5738175	29258434	YQ	2	participated in experiments and analyzed the data	participated in experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6397506	30823922	CJ	2	conceived the paper and jointly drafted and reviewed the content|worked on acquisition of the data	conceived the paper and jointly drafted and reviewed the content	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
6397506	30823922	CJ	2	conceived the paper and jointly drafted and reviewed the content|worked on acquisition of the data	worked on acquisition of the data	Performed the experiments	Investigation	YES
6397506	30823922	LE	2	worked on acquisition of the data|worked on the active and placebo supplements|contributed equally to this research, both can be considered as first authors	worked on acquisition of the data	Performed the experiments	Investigation	YES
6397506	30823922	LE	2	worked on acquisition of the data|worked on the active and placebo supplements|contributed equally to this research, both can be considered as first authors	worked on the active and placebo supplements	Performed the experiments	-	YES
6397506	30823922	LE	2	worked on acquisition of the data|worked on the active and placebo supplements|contributed equally to this research, both can be considered as first authors	contributed equally to this research, both can be considered as first authors	-	-	NO
6397506	30823922	NB	2	conceived the paper and jointly drafted and reviewed the content	conceived the paper and jointly drafted and reviewed the content	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
6397506	30823922	RH	2	conceived the paper and jointly drafted and reviewed the content|conceived the approach to data analysis	conceived the paper and jointly drafted and reviewed the content	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
6397506	30823922	RH	2	conceived the paper and jointly drafted and reviewed the content|conceived the approach to data analysis	conceived the approach to data analysis	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
6397506	30823922	SG	2	conceived the paper and jointly drafted and reviewed the content|contributed equally to this research, both can be considered as first authors	conceived the paper and jointly drafted and reviewed the content	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
6397506	30823922	SG	2	conceived the paper and jointly drafted and reviewed the content|contributed equally to this research, both can be considered as first authors	contributed equally to this research, both can be considered as first authors	-	-	NO
5799227	29449862	BF	2	designed the experiments and wrote the manuscript	designed the experiments and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5799227	29449862	FH	2	provided assistance on the drought phenotyping experiment	provided assistance on the drought phenotyping experiment	Performed the experiments	Investigation	YES
5799227	29449862	FS	2	provided assistance on vector construction	provided assistance on vector construction	Performed the experiments	Investigation	YES
5799227	29449862	LH	2	generated the transgenic materials, designed and performed the experiments	generated the transgenic materials, designed and performed the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5799227	29449862	QQ	2	provided assistance on vector construction	provided assistance on vector construction	Performed the experiments	Investigation	YES
5799227	29449862	WW	2	analyzed rna seq data	analyzed rna seq data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5799227	29449862	XZ	2	provided assistance on the drought phenotyping experiment	provided assistance on the drought phenotyping experiment	Performed the experiments	Investigation	YES
5799227	29449862	YW	2	generated the transgenic materials, designed and performed the experiments	generated the transgenic materials, designed and performed the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5799227	29449862	YZ	2	provided assistance on the drought phenotyping experiment	provided assistance on the drought phenotyping experiment	Performed the experiments	Investigation	YES
5799227	29449862	ZL	2	designed the experiments and wrote the manuscript	designed the experiments and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5799227	29449862	ZcL	2	analyzed rna seq data	analyzed rna seq data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5567581	28831769	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5567581	28831769	BJL	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5567581	28831769	CML	2	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5567581	28831769	JL	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5567581	28831769	LS	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5567581	28831769	RJ	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5567581	28831769	YL	2	planned and carried out the experiments, analyzed the data and wrote the manuscript	planned and carried out the experiments, analyzed the data and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
5567581	28831769	YlW	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5567581	28831769	ZBG	2	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5567581	28831769	ZFL	2	participated in the data analysis and finalized the manuscript	participated in the data analysis and finalized the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
1959185	17848998	CM	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1959185	17848998	FD	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1959185	17848998	FF	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1959185	17848998	FF	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1959185	17848998	FM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1959185	17848998	FM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1959185	17848998	FM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1959185	17848998	FM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1959185	17848998	GC	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1959185	17848998	GL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1959185	17848998	LD	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1959185	17848998	LN	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1959185	17848998	LN	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1959185	17848998	MB	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1959185	17848998	MC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1959185	17848998	MF	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1959185	17848998	MF	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1959185	17848998	SF	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416771	25933112	CRX	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416771	25933112	SZ	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416771	25933112	WXZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416771	25933112	XMW	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416771	25933112	XQC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416771	25933112	YPX	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416771	25933112	ZFH	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416771	25933112	ZFH	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416771	25933112	ZYY	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
6270686	25178059	Alessandra Montalbano	PLoS52	designed research|performed research and analyzed the data|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
6270686	25178059	Alessandra Montalbano	PLoS52	designed research|performed research and analyzed the data|wrote the paper	performed research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270686	25178059	Alessandra Montalbano	PLoS52	designed research|performed research and analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270686	25178059	Anna Carbone	PLoS52	performed research and analyzed the data	performed research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270686	25178059	Barbara Parrino	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270686	25178059	Girolamo Cirrincione	PLoS52	designed research|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
6270686	25178059	Girolamo Cirrincione	PLoS52	designed research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270686	25178059	Paola Barraja	PLoS52	designed research|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
6270686	25178059	Paola Barraja	PLoS52	designed research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270686	25178059	Patrizia Diana	PLoS52	designed research|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
6270686	25178059	Patrizia Diana	PLoS52	designed research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270686	25178059	Virginia Spano	PLoS52	performed research and analyzed the data	performed research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6429762	30898134	AG	PLoS52	performed the study	performed the study	Performed the experiments	Investigation	YES
6429762	30898134	AZ	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
6429762	30898134	ESK	PLoS52	conceived and designed the study|performed the study|analyzed the data|wrote the paper	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6429762	30898134	ESK	PLoS52	conceived and designed the study|performed the study|analyzed the data|wrote the paper	performed the study	Performed the experiments	Investigation	YES
6429762	30898134	ESK	PLoS52	conceived and designed the study|performed the study|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
6429762	30898134	ESK	PLoS52	conceived and designed the study|performed the study|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6429762	30898134	IP	PLoS52	performed the study|analyzed the data	performed the study	Performed the experiments	Investigation	YES
6429762	30898134	IP	PLoS52	performed the study|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
6429762	30898134	PD	PLoS52	conceived and designed the study|performed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6429762	30898134	PD	PLoS52	conceived and designed the study|performed the study	performed the study	Performed the experiments	Investigation	YES
6429762	30898134	TP	PLoS52	performed the study	performed the study	Performed the experiments	Investigation	YES
5799232	29449853	AB	2	as the plant physiologist, contributed phenological phs data and the interpretation thereof	as the plant physiologist, contributed phenological phs data and the interpretation thereof	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5799232	29449853	Both authors	2	have contributed to the work and agreed to be in the author list|contributed to the writing of the manuscript and preparing it for publication	have contributed to the work and agreed to be in the author list	-	-	NO
5799232	29449853	Both authors	2	have contributed to the work and agreed to be in the author list|contributed to the writing of the manuscript and preparing it for publication	contributed to the writing of the manuscript and preparing it for publication	Wrote the paper	Writing - Original Draft	YES
5799232	29449853	SS	2	is the molecular scientist and contributed molecular data and the interpretation thereof	is the molecular scientist and contributed molecular data and the interpretation thereof	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5799232	29449853	The authors	2	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	Performed the experiments	Investigation	YES
4810817	26977064	A.F.	2	provided the palaeoenvironment data and the palaeo-coordinates	provided the palaeoenvironment data and the palaeo-coordinates	Contributed reagents/materials/analysis tools	Project administration|Resources	YES
4810817	26977064	A.P.	2	conceived the project|contributed to the drafting of the manuscript	conceived the project	Conceived and designed the experiments	Conceptualization	YES
4810817	26977064	A.P.	2	conceived the project|contributed to the drafting of the manuscript	contributed to the drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
4810817	26977064	All authors	2	commented on the manuscript and gave final approval for publication	commented on the manuscript and gave final approval for publication	-	-	NO
4810817	26977064	D.J.L.	2	provided the palaeoenvironment data and the palaeo-coordinates	provided the palaeoenvironment data and the palaeo-coordinates	Contributed reagents/materials/analysis tools	Project administration|Resources	YES
4810817	26977064	I.S.F.	2	conceived the project|collated the eocene pf data and ran the analysis|contributed to the drafting of the manuscript	conceived the project	Conceived and designed the experiments	Conceptualization	YES
4810817	26977064	I.S.F.	2	conceived the project|collated the eocene pf data and ran the analysis|contributed to the drafting of the manuscript	collated the eocene pf data and ran the analysis	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
4810817	26977064	I.S.F.	2	conceived the project|collated the eocene pf data and ran the analysis|contributed to the drafting of the manuscript	contributed to the drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
4810817	26977064	P.M.	2	provided the palaeoenvironment data and the palaeo-coordinates	provided the palaeoenvironment data and the palaeo-coordinates	Contributed reagents/materials/analysis tools	Project administration|Resources	YES
4810817	26977064	P.N.P.	2	contributed to the drafting of the manuscript	contributed to the drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
4810817	26977064	T.D.J.	2	contributed to the drafting of the manuscript	contributed to the drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
1959240	17848988	RC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1959240	17848988	RC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1959240	17848988	RC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1959240	17848988	SC	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1959240	17848988	SC	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1959240	17848988	SP	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1959240	17848988	SP	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1959240	17848988	SP	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5983119	29764981	AA-A	CRediT	Conceptualisation|Methodology|Formal analysis|Investigation|Writing - original draft|Writing - review & editing|Supervision	Conceptualisation	Conceived and designed the experiments	Conceptualization	YES
5983119	29764981	AA-A	CRediT	Conceptualisation|Methodology|Formal analysis|Investigation|Writing - original draft|Writing - review & editing|Supervision	Methodology	Performed the experiments	Methodology	YES
5983119	29764981	AA-A	CRediT	Conceptualisation|Methodology|Formal analysis|Investigation|Writing - original draft|Writing - review & editing|Supervision	Formal analysis	Analyzed the data	Formal analysis	YES
5983119	29764981	AA-A	CRediT	Conceptualisation|Methodology|Formal analysis|Investigation|Writing - original draft|Writing - review & editing|Supervision	Investigation	Performed the experiments	Investigation	YES
5983119	29764981	AA-A	CRediT	Conceptualisation|Methodology|Formal analysis|Investigation|Writing - original draft|Writing - review & editing|Supervision	Writing - original draft	Wrote the paper	Writing - Original Draft	YES
5983119	29764981	AA-A	CRediT	Conceptualisation|Methodology|Formal analysis|Investigation|Writing - original draft|Writing - review & editing|Supervision	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
5983119	29764981	AA-A	CRediT	Conceptualisation|Methodology|Formal analysis|Investigation|Writing - original draft|Writing - review & editing|Supervision	Supervision	-	Supervision	YES
5983119	29764981	ACa	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
5983119	29764981	ACh	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
5983119	29764981	AEC	CRediT	Methodology|Formal analysis|Investigation	Methodology	Performed the experiments	Methodology	YES
5983119	29764981	AEC	CRediT	Methodology|Formal analysis|Investigation	Formal analysis	Analyzed the data	Formal analysis	YES
5983119	29764981	AEC	CRediT	Methodology|Formal analysis|Investigation	Investigation	Performed the experiments	Investigation	YES
5983119	29764981	AM-G	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
5983119	29764981	AMI	CRediT	Investigation|Writing - review & editing	Investigation	Performed the experiments	Investigation	YES
5983119	29764981	AMI	CRediT	Investigation|Writing - review & editing	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
5983119	29764981	AMM	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
5983119	29764981	AU	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
5983119	29764981	BK	CRediT	Formal analysis|Investigation	Formal analysis	Analyzed the data	Formal analysis	YES
5983119	29764981	BK	CRediT	Formal analysis|Investigation	Investigation	Performed the experiments	Investigation	YES
5983119	29764981	CB	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
5983119	29764981	DEH	CRediT	Formal analysis	Formal analysis	Analyzed the data	Formal analysis	YES
5983119	29764981	EB	CRediT	Methodology|Formal analysis|Investigation|Writing - review & editing|Writing - review & editing|Supervision	Methodology	Performed the experiments	Methodology	YES
5983119	29764981	EB	CRediT	Methodology|Formal analysis|Investigation|Writing - review & editing|Writing - review & editing|Supervision	Formal analysis	Analyzed the data	Formal analysis	YES
5983119	29764981	EB	CRediT	Methodology|Formal analysis|Investigation|Writing - review & editing|Writing - review & editing|Supervision	Investigation	Performed the experiments	Investigation	YES
5983119	29764981	EB	CRediT	Methodology|Formal analysis|Investigation|Writing - review & editing|Writing - review & editing|Supervision	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
5983119	29764981	EB	CRediT	Methodology|Formal analysis|Investigation|Writing - review & editing|Writing - review & editing|Supervision	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
5983119	29764981	EB	CRediT	Methodology|Formal analysis|Investigation|Writing - review & editing|Writing - review & editing|Supervision	Supervision	-	Supervision	YES
5983119	29764981	EMCF	CRediT	Conceptualisation|Methodology|Formal analysis|Writing - review & editing|Supervision	Conceptualisation	Conceived and designed the experiments	Conceptualization	YES
5983119	29764981	EMCF	CRediT	Conceptualisation|Methodology|Formal analysis|Writing - review & editing|Supervision	Methodology	Performed the experiments	Methodology	YES
5983119	29764981	EMCF	CRediT	Conceptualisation|Methodology|Formal analysis|Writing - review & editing|Supervision	Formal analysis	Analyzed the data	Formal analysis	YES
5983119	29764981	EMCF	CRediT	Conceptualisation|Methodology|Formal analysis|Writing - review & editing|Supervision	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
5983119	29764981	EMCF	CRediT	Conceptualisation|Methodology|Formal analysis|Writing - review & editing|Supervision	Supervision	-	Supervision	YES
5983119	29764981	EPa	CRediT	Formal analysis|Investigation	Formal analysis	Analyzed the data	Formal analysis	YES
5983119	29764981	EPa	CRediT	Formal analysis|Investigation	Investigation	Performed the experiments	Investigation	YES
5983119	29764981	EPe	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
5983119	29764981	EW	CRediT	Formal analysis|Investigation	Formal analysis	Analyzed the data	Formal analysis	YES
5983119	29764981	EW	CRediT	Formal analysis|Investigation	Investigation	Performed the experiments	Investigation	YES
5983119	29764981	FB	CRediT	Methodology|Formal analysis|Writing - review & editing	Methodology	Performed the experiments	Methodology	YES
5983119	29764981	FB	CRediT	Methodology|Formal analysis|Writing - review & editing	Formal analysis	Analyzed the data	Formal analysis	YES
5983119	29764981	FB	CRediT	Methodology|Formal analysis|Writing - review & editing	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
5983119	29764981	GC	CRediT	Formal analysis|Investigation	Formal analysis	Analyzed the data	Formal analysis	YES
5983119	29764981	GC	CRediT	Formal analysis|Investigation	Investigation	Performed the experiments	Investigation	YES
5983119	29764981	HO	CRediT	Methodology|Formal analysis|Investigation|Writing - review & editing	Methodology	Performed the experiments	Methodology	YES
5983119	29764981	HO	CRediT	Methodology|Formal analysis|Investigation|Writing - review & editing	Formal analysis	Analyzed the data	Formal analysis	YES
5983119	29764981	HO	CRediT	Methodology|Formal analysis|Investigation|Writing - review & editing	Investigation	Performed the experiments	Investigation	YES
5983119	29764981	HO	CRediT	Methodology|Formal analysis|Investigation|Writing - review & editing	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
5983119	29764981	JH	CRediT	Methodology|Formal analysis|Writing - review & editing	Methodology	Performed the experiments	Methodology	YES
5983119	29764981	JH	CRediT	Methodology|Formal analysis|Writing - review & editing	Formal analysis	Analyzed the data	Formal analysis	YES
5983119	29764981	JH	CRediT	Methodology|Formal analysis|Writing - review & editing	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
5983119	29764981	JM	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
5983119	29764981	JMB-A	CRediT	Formal analysis|Investigation	Formal analysis	Analyzed the data	Formal analysis	YES
5983119	29764981	JMB-A	CRediT	Formal analysis|Investigation	Investigation	Performed the experiments	Investigation	YES
5983119	29764981	KL	CRediT	Methodology|Formal analysis|Writing - review & editing	Methodology	Performed the experiments	Methodology	YES
5983119	29764981	KL	CRediT	Methodology|Formal analysis|Writing - review & editing	Formal analysis	Analyzed the data	Formal analysis	YES
5983119	29764981	KL	CRediT	Methodology|Formal analysis|Writing - review & editing	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
5983119	29764981	LG	CRediT	Methodology|Formal analysis	Methodology	Performed the experiments	Methodology	YES
5983119	29764981	LG	CRediT	Methodology|Formal analysis	Formal analysis	Analyzed the data	Formal analysis	YES
5983119	29764981	LT	CRediT	Methodology	Methodology	Performed the experiments	Methodology	YES
5983119	29764981	MG	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
5983119	29764981	MH	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
5983119	29764981	ML	CRediT	Methodology|Formal analysis	Methodology	Performed the experiments	Methodology	YES
5983119	29764981	ML	CRediT	Methodology|Formal analysis	Formal analysis	Analyzed the data	Formal analysis	YES
5983119	29764981	MS	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
5983119	29764981	NB	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
5983119	29764981	NLF	CRediT	Writing - review & editing	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
5983119	29764981	PF	CRediT	Conceptualisation|Methodology|Formal analysis|Investigation|Writing - original draft|Writing - review & editing|Supervision	Conceptualisation	Conceived and designed the experiments	Conceptualization	YES
5983119	29764981	PF	CRediT	Conceptualisation|Methodology|Formal analysis|Investigation|Writing - original draft|Writing - review & editing|Supervision	Methodology	Performed the experiments	Methodology	YES
5983119	29764981	PF	CRediT	Conceptualisation|Methodology|Formal analysis|Investigation|Writing - original draft|Writing - review & editing|Supervision	Formal analysis	Analyzed the data	Formal analysis	YES
5983119	29764981	PF	CRediT	Conceptualisation|Methodology|Formal analysis|Investigation|Writing - original draft|Writing - review & editing|Supervision	Investigation	Performed the experiments	Investigation	YES
5983119	29764981	PF	CRediT	Conceptualisation|Methodology|Formal analysis|Investigation|Writing - original draft|Writing - review & editing|Supervision	Writing - original draft	Wrote the paper	Writing - Original Draft	YES
5983119	29764981	PF	CRediT	Conceptualisation|Methodology|Formal analysis|Investigation|Writing - original draft|Writing - review & editing|Supervision	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
5983119	29764981	PF	CRediT	Conceptualisation|Methodology|Formal analysis|Investigation|Writing - original draft|Writing - review & editing|Supervision	Supervision	-	Supervision	YES
5983119	29764981	PSi	CRediT	Methodology|Formal analysis|Investigation|Writing - review & editing	Methodology	Performed the experiments	Methodology	YES
5983119	29764981	PSi	CRediT	Methodology|Formal analysis|Investigation|Writing - review & editing	Formal analysis	Analyzed the data	Formal analysis	YES
5983119	29764981	PSi	CRediT	Methodology|Formal analysis|Investigation|Writing - review & editing	Investigation	Performed the experiments	Investigation	YES
5983119	29764981	PSi	CRediT	Methodology|Formal analysis|Investigation|Writing - review & editing	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
5983119	29764981	PSt	CRediT	Formal analysis|Investigation	Formal analysis	Analyzed the data	Formal analysis	YES
5983119	29764981	PSt	CRediT	Formal analysis|Investigation	Investigation	Performed the experiments	Investigation	YES
5983119	29764981	RF	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
5983119	29764981	SC	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
5983119	29764981	TC	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
5983119	29764981	TR	CRediT	Methodology|Formal analysis|Investigation|Writing - review & editing	Methodology	Performed the experiments	Methodology	YES
5983119	29764981	TR	CRediT	Methodology|Formal analysis|Investigation|Writing - review & editing	Formal analysis	Analyzed the data	Formal analysis	YES
5983119	29764981	TR	CRediT	Methodology|Formal analysis|Investigation|Writing - review & editing	Investigation	Performed the experiments	Investigation	YES
5983119	29764981	TR	CRediT	Methodology|Formal analysis|Investigation|Writing - review & editing	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
5983119	29764981	VP	CRediT	Methodology|Formal analysis|Writing - review & editing|Supervision	Methodology	Performed the experiments	Methodology	YES
5983119	29764981	VP	CRediT	Methodology|Formal analysis|Writing - review & editing|Supervision	Formal analysis	Analyzed the data	Formal analysis	YES
5983119	29764981	VP	CRediT	Methodology|Formal analysis|Writing - review & editing|Supervision	Writing - review & editing	Wrote the paper	Writing - Review & Editing	YES
5983119	29764981	VP	CRediT	Methodology|Formal analysis|Writing - review & editing|Supervision	Supervision	-	Supervision	YES
5983119	29764981	WE	CRediT	Formal analysis|Investigation	Formal analysis	Analyzed the data	Formal analysis	YES
5983119	29764981	WE	CRediT	Formal analysis|Investigation	Investigation	Performed the experiments	Investigation	YES
5983119	29764981	YG	CRediT	Methodology|Investigation	Methodology	Performed the experiments	Methodology	YES
5983119	29764981	YG	CRediT	Methodology|Investigation	Investigation	Performed the experiments	Investigation	YES
5983119	29764981	YY	CRediT	Formal analysis|Investigation	Formal analysis	Analyzed the data	Formal analysis	YES
5983119	29764981	YY	CRediT	Formal analysis|Investigation	Investigation	Performed the experiments	Investigation	YES
5738178	29258426	FYP	1	Performed the analyses	Performed the analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5738178	29258426	RCY	1	Conceived and designed the study|Writing of the manuscript	Conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5738178	29258426	RCY	1	Conceived and designed the study|Writing of the manuscript	Writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5738178	29258426	ZH	1	Performed the analyses	Performed the analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6349015	30774925	All authors	PLoS52	have discussed the results and made comments on the manuscript	have discussed the results and made comments on the manuscript	-	-	NO
6349015	30774925	C.L.	PLoS52	wrote the manuscript|conceived the whole project	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6349015	30774925	C.L.	PLoS52	wrote the manuscript|conceived the whole project	conceived the whole project	Conceived and designed the experiments	Conceptualization	YES
6349015	30774925	H.C.	PLoS52	performed the experiments|collected and analyzed the data|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
6349015	30774925	H.C.	PLoS52	performed the experiments|collected and analyzed the data|wrote the manuscript	collected and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6349015	30774925	H.C.	PLoS52	performed the experiments|collected and analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6349015	30774925	J.L.	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
6349015	30774925	L.Q.	PLoS52	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
6349015	30774925	W.D.	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
6434855	30909945	All authors	2	participated at the conception and design of the study|participated at data interpretation and analysis	participated at the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6434855	30909945	All authors	2	participated at the conception and design of the study|participated at data interpretation and analysis	participated at data interpretation and analysis	Analyzed the data	Formal analysis	YES
6434855	30909945	EC	2	participated at manuscript drafting	participated at manuscript drafting	Wrote the paper	Writing - Original Draft	YES
6434855	30909945	ER	2	were involved at data collection|participated at manuscript drafting	were involved at data collection	Performed the experiments	Investigation	YES
6434855	30909945	ER	2	were involved at data collection|participated at manuscript drafting	participated at manuscript drafting	Wrote the paper	Writing - Original Draft	YES
6434855	30909945	LN	2	were involved at data collection	were involved at data collection	Performed the experiments	Investigation	YES
6434855	30909945	OS	2	participated at manuscript drafting	participated at manuscript drafting	Wrote the paper	Writing - Original Draft	YES
6434855	30909945	SV	2	participated at manuscript drafting	participated at manuscript drafting	Wrote the paper	Writing - Original Draft	YES
5568183	28836182	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5568183	28836182	FSC	2	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5568183	28836182	HHL	2	assisted to carry out experiments	assisted to carry out experiments	Performed the experiments	Investigation	YES
5568183	28836182	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5568183	28836182	YCS	2	participated in the data analysis and wrote the manuscript	participated in the data analysis and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5568183	28836182	YXZ	2	carried out the nmr experiments	carried out the nmr experiments	Performed the experiments	Investigation	YES
5568183	28836182	ZJM	2	assisted to carry out experiments	assisted to carry out experiments	Performed the experiments	Investigation	YES
4416772	25933107	FBT	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416772	25933107	JLM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416772	25933107	KFP	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416772	25933107	KFP	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416772	25933107	LZ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416772	25933107	TZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416772	25933107	WCY	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416772	25933107	WCY	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416772	25933107	YMW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416772	25933107	YMW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4416772	25933107	YMW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4416772	25933107	YMW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416772	25933107	YZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416772	25933107	ZXL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416772	25933107	ZXL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416772	25933107	ZXL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416772	25933107	ZXL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416772	25933107	ZXL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1959241	17846664	AA	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1959241	17846664	AA	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1959241	17846664	AB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1959241	17846664	AN	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1959241	17846664	AN	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1959241	17846664	AS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1959241	17846664	BE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1959241	17846664	BE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1959241	17846664	BE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1959241	17846664	BE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1959241	17846664	BV	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1959241	17846664	BV	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1959241	17846664	BV	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1959241	17846664	EB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1959241	17846664	EB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1959241	17846664	EB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1959241	17846664	EB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1959241	17846664	EP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1959241	17846664	EP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1959241	17846664	EP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1959241	17846664	FH	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1959241	17846664	KG	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1959241	17846664	KG	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1959241	17846664	MD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1959241	17846664	MD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1959241	17846664	MD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1959241	17846664	MS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1959241	17846664	SH	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1959241	17846664	WP	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1959241	17846664	WP	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5738194	29258435	JS	PLoS52	designed all the experiments in their entirety|carried out the experiments|analyzed the data|wrote the manuscript	designed all the experiments in their entirety	Conceived and designed the experiments	Methodology	YES
5738194	29258435	JS	PLoS52	designed all the experiments in their entirety|carried out the experiments|analyzed the data|wrote the manuscript	carried out the experiments	Performed the experiments	Investigation	YES
5738194	29258435	JS	PLoS52	designed all the experiments in their entirety|carried out the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5738194	29258435	JS	PLoS52	designed all the experiments in their entirety|carried out the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5738194	29258435	JZ	PLoS52	designed all the experiments in their entirety|reviewed the manuscript	designed all the experiments in their entirety	Conceived and designed the experiments	Methodology	YES
5738194	29258435	JZ	PLoS52	designed all the experiments in their entirety|reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5738194	29258435	KZ	PLoS52	designed all the experiments in their entirety|reviewed the manuscript	designed all the experiments in their entirety	Conceived and designed the experiments	Methodology	YES
5738194	29258435	KZ	PLoS52	designed all the experiments in their entirety|reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5738194	29258435	YZ	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5799261	29449859	LS	2	conceived and designed the experiment|wrote the manuscript, other authors provided editorial advise	conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5799261	29449859	LS	2	conceived and designed the experiment|wrote the manuscript, other authors provided editorial advise	wrote the manuscript, other authors provided editorial advise	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5799261	29449859	MvK	2	conceived and designed the experiment|wrote the manuscript, other authors provided editorial advise	conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5799261	29449859	MvK	2	conceived and designed the experiment|wrote the manuscript, other authors provided editorial advise	wrote the manuscript, other authors provided editorial advise	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5799261	29449859	PH	2	conceived and designed the experiment	conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5799261	29449859	TB	2	conceived and designed the experiment|wrote the manuscript, other authors provided editorial advise	conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5799261	29449859	TB	2	conceived and designed the experiment|wrote the manuscript, other authors provided editorial advise	wrote the manuscript, other authors provided editorial advise	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6270688	24759068	AMG	2	conceived the study|participated in the design of the study and coordination	conceived the study	Conceived and designed the experiments	Conceptualization	YES
6270688	24759068	AMG	2	conceived the study|participated in the design of the study and coordination	participated in the design of the study and coordination	Conceived and designed the experiments	Methodology|Project administration	YES
6270688	24759068	AMH	2	conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
6270688	24759068	CB	2	performed the in vivo and in vitro experiments	performed the in vivo and in vitro experiments	Performed the experiments	Investigation	YES
6270688	24759068	FI	2	performed the in vivo and in vitro experiments	performed the in vivo and in vitro experiments	Performed the experiments	Investigation	YES
6270688	24759068	GDM	2	performed the in vivo and in vitro experiments	performed the in vivo and in vitro experiments	Performed the experiments	Investigation	YES
6270688	24759068	LM	2	performed the in vivo and in vitro experiments	performed the in vivo and in vitro experiments	Performed the experiments	Investigation	YES
6270688	24759068	MCG	2	performed the in vivo and in vitro experiments|participated in the design of the study and coordination	performed the in vivo and in vitro experiments	Performed the experiments	Investigation	YES
6270688	24759068	MCG	2	performed the in vivo and in vitro experiments|participated in the design of the study and coordination	participated in the design of the study and coordination	Conceived and designed the experiments	Methodology|Project administration	YES
6449982	30947727	DAK	2	co-designed the study, supervised experiments in the exercise lab, and was a contributor in writing and revising the manuscript	co-designed the study, supervised experiments in the exercise lab, and was a contributor in writing and revising the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
6449982	30947727	EC	2	oversaw completion of the exercise protocols, collected, analyzed, and interpreted participant data and saliva samples	oversaw completion of the exercise protocols, collected, analyzed, and interpreted participant data and saliva samples	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology|Supervision	YES
6449982	30947727	EH	2	significantly contributed to the interpretation of the data, and the drafting and revision of the manuscript	significantly contributed to the interpretation of the data, and the drafting and revision of the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft|Writing - Review & Editing	YES
6449982	30947727	JPK	2	co-designed the study, and supervised all research and statistical analysis of the data	co-designed the study, and supervised all research and statistical analysis of the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology|Supervision	YES
6449982	30947727	MPK	2	significantly contributed to the interpretation of the data, and the drafting and revision of the manuscript	significantly contributed to the interpretation of the data, and the drafting and revision of the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft|Writing - Review & Editing	YES
6449982	30947727	PRH	2	oversaw completion of the exercise protocols, collected and analyzed participant data and saliva samples, and was the major contributor in writing the manuscript	oversaw completion of the exercise protocols, collected and analyzed participant data and saliva samples, and was the major contributor in writing the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Supervision|Writing - Original Draft	YES
6449982	30947727	SNW	2	assisted with the exercise experiments, collected and analyzed saliva samples, and contributed to the revision of the manuscript	assisted with the exercise experiments, collected and analyzed saliva samples, and contributed to the revision of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
6449982	30947727	ZIK	2	acted as the responsible physician for the study, and significantly contributed to the drafting and revision of the manuscript	acted as the responsible physician for the study, and significantly contributed to the drafting and revision of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4416773	25932917	CLH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416773	25932917	CLH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416773	25932917	CLH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416773	25932917	CLH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416773	25932917	CYO	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416773	25932917	CYO	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416773	25932917	CYO	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416773	25932917	JYC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416773	25932917	JYC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416773	25932917	JYC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5574827	28853018	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5574827	28853018	BMK	PLoS52	performed the research|analyzed the data	performed the research	Performed the experiments	Investigation	YES
5574827	28853018	BMK	PLoS52	performed the research|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5574827	28853018	HYC	PLoS52	performed the research|analyzed the data	performed the research	Performed the experiments	Investigation	YES
5574827	28853018	HYC	PLoS52	performed the research|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5574827	28853018	JSK	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5574827	28853018	WGK	PLoS52	designed the research and wrote the paper|analyzed the data	designed the research and wrote the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5574827	28853018	WGK	PLoS52	designed the research and wrote the paper|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5983126	29712715	DR	PLoS52	designed and performed biochemistry and imaging experiments|wrote the paper	designed and performed biochemistry and imaging experiments	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Investigation|Methodology|Visualization	YES
5983126	29712715	DR	PLoS52	designed and performed biochemistry and imaging experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5983126	29712715	GLC	PLoS52	supervised electrophysiology experiments	supervised electrophysiology experiments	Performed the experiments	Investigation|Supervision	YES
5983126	29712715	JGH	PLoS52	designed and supervised the experiments and supervised the project|wrote the paper	designed and supervised the experiments and supervised the project	Conceived and designed the experiments	Methodology|Supervision	YES
5983126	29712715	JGH	PLoS52	designed and supervised the experiments and supervised the project|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5983126	29712715	MA	PLoS52	designed and performed electrophysiology experiments	designed and performed electrophysiology experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5983126	29712715	TMS	PLoS52	designed and performed electrophysiology experiments	designed and performed electrophysiology experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3884780	24453820	Chikara Ohyama	2	was responsible for the concept and design of the study, the interpretation of data, and critical revision of the paper	was responsible for the concept and design of the study, the interpretation of data, and critical revision of the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Review & Editing	YES
3884780	24453820	Hisao Saitoh	2	performed clinical followup and contributed data for the paper	performed clinical followup and contributed data for the paper	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
3884780	24453820	Kanemitsu Yamaya	2	participated in the subject recruitment	participated in the subject recruitment	Performed the experiments	Investigation	YES
3884780	24453820	Maho Amano	2	participated in drafting of the paper	participated in drafting of the paper	Wrote the paper	Writing - Original Draft	YES
3884780	24453820	Megumi Tsushima	2	performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
3884780	24453820	Shin-Ichiro Nishimura	2	supervised the study	supervised the study	-	Supervision	YES
3884780	24453820	Shingo Hatakeyama	2	performed clinical followup and statistical analysis and drafted the paper	performed clinical followup and statistical analysis and drafted the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3884780	24453820	Takuya Koie	2	performed clinical followup and contributed data for the paper	performed clinical followup and contributed data for the paper	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
3884780	24453820	Tohru Yoneyama	2	performed the glycoblotting analysis|performed clinical followup and contributed data for the paper	performed the glycoblotting analysis	Performed the experiments	Investigation	YES
3884780	24453820	Tohru Yoneyama	2	performed the glycoblotting analysis|performed clinical followup and contributed data for the paper	performed clinical followup and contributed data for the paper	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
3884780	24453820	Tomihisa Funyu	2	supervised the study	supervised the study	-	Supervision	YES
3884780	24453820	Yasuhiro Hashimoto	2	performed clinical followup and contributed data for the paper	performed clinical followup and contributed data for the paper	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
3884780	24453820	Yuki Tobisawa	2	performed the glycoblotting analysis	performed the glycoblotting analysis	Performed the experiments	Investigation	YES
5799269	29449861	AF	PLoS52	designed and carried out the field trials and plant investigations	designed and carried out the field trials and plant investigations	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5799269	29449861	All authors	PLoS52	read the manuscript and approved the submission	read the manuscript and approved the submission	-	-	NO
5799269	29449861	IC	PLoS52	designed and conducted pot experiment and capacitance measurements, discussed the results and wrote the paper	designed and conducted pot experiment and capacitance measurements, discussed the results and wrote the paper	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5799269	29449861	KR	PLoS52	supervised the project and helped in data interpretation	supervised the project and helped in data interpretation	Analyzed the data	Formal analysis|Supervision	YES
5799269	29449861	KS	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5799269	29449861	PM	PLoS52	designed and carried out the field trials and plant investigations	designed and carried out the field trials and plant investigations	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5799269	29449861	RK	PLoS52	designed and carried out the field trials and plant investigations	designed and carried out the field trials and plant investigations	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5799269	29449861	TT	PLoS52	designed and supervised soybean experiment and helped in writing paper	designed and supervised soybean experiment and helped in writing paper	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Original Draft	YES
6349023	30774918	A.J.	2	investigated the characteristics of the uc-pb nanoprobes	investigated the characteristics of the uc-pb nanoprobes	Performed the experiments	Investigation	YES
6349023	30774918	All authors	2	contributed to the preparation of the original and revised manuscripts	contributed to the preparation of the original and revised manuscripts	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6349023	30774918	F.M.	2	investigated the characteristics of the uc-pb nanoprobes	investigated the characteristics of the uc-pb nanoprobes	Performed the experiments	Investigation	YES
6349023	30774918	J.Z.	2	conceived the project, analyzed the results, and wrote the original manuscript	conceived the project, analyzed the results, and wrote the original manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
6349023	30774918	Q.J.	2	synthesized the uc-pb nanoprobes|conducted the other experiments	synthesized the uc-pb nanoprobes	Performed the experiments	Investigation	YES
6349023	30774918	Q.J.	2	synthesized the uc-pb nanoprobes|conducted the other experiments	conducted the other experiments	Performed the experiments	Investigation	YES
6349023	30774918	X.Z.	2	synthesized the uc-pb nanoprobes|performed ucl imaging in vitro and in vivo	synthesized the uc-pb nanoprobes	Performed the experiments	Investigation	YES
6349023	30774918	X.Z.	2	synthesized the uc-pb nanoprobes|performed ucl imaging in vitro and in vivo	performed ucl imaging in vitro and in vivo	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
6349023	30774918	Y.L.	2	conceived the project, analyzed the results, and wrote the original manuscript|synthesized the uc-pb nanoprobes|investigated the characteristics of the uc-pb nanoprobes|performed ucl imaging in vitro and in vivo|conducted the other experiments	conceived the project, analyzed the results, and wrote the original manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
6349023	30774918	Y.L.	2	conceived the project, analyzed the results, and wrote the original manuscript|synthesized the uc-pb nanoprobes|investigated the characteristics of the uc-pb nanoprobes|performed ucl imaging in vitro and in vivo|conducted the other experiments	synthesized the uc-pb nanoprobes	Performed the experiments	Investigation	YES
6349023	30774918	Y.L.	2	conceived the project, analyzed the results, and wrote the original manuscript|synthesized the uc-pb nanoprobes|investigated the characteristics of the uc-pb nanoprobes|performed ucl imaging in vitro and in vivo|conducted the other experiments	investigated the characteristics of the uc-pb nanoprobes	Performed the experiments	Investigation	YES
6349023	30774918	Y.L.	2	conceived the project, analyzed the results, and wrote the original manuscript|synthesized the uc-pb nanoprobes|investigated the characteristics of the uc-pb nanoprobes|performed ucl imaging in vitro and in vivo|conducted the other experiments	performed ucl imaging in vitro and in vivo	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
6349023	30774918	Y.L.	2	conceived the project, analyzed the results, and wrote the original manuscript|synthesized the uc-pb nanoprobes|investigated the characteristics of the uc-pb nanoprobes|performed ucl imaging in vitro and in vivo|conducted the other experiments	conducted the other experiments	Performed the experiments	Investigation	YES
6270689	25014531	All authors	2	conceived and designed the experiments and contributed to data analysis and interpretation of the results	conceived and designed the experiments and contributed to data analysis and interpretation of the results	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
5738906	29262782	BL	2	performed most of the experiments and analyses including data generation, computational analysis, methodological application and writing the original draft	performed most of the experiments and analyses including data generation, computational analysis, methodological application and writing the original draft	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5738906	29262782	DHC	2	participated in conceptualizing the project, supervising the work, and reviewing and editing of the manuscript	participated in conceptualizing the project, supervising the work, and reviewing and editing of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Supervision|Writing - Review & Editing	YES
5738906	29262782	DK	2	participated in conceptualizing the project, supervising the work, and reviewing and editing of the manuscript	participated in conceptualizing the project, supervising the work, and reviewing and editing of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Supervision|Writing - Review & Editing	YES
5738906	29262782	KB	2	participated in data generation, as well as review and editing of the manuscript	participated in data generation, as well as review and editing of the manuscript	Wrote the paper	Writing - Review & Editing	YES
1959242	17786207	GS	PLoS5	Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1959242	17786207	GS	PLoS5	Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1959242	17786207	GS	PLoS5	Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1959242	17786207	GS	PLoS5	Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1959242	17786207	MR	PLoS5	Performed the experiments|Analyzed the data|Prepared the figures|Contributed to paper writing	Performed the experiments	Performed the experiments	Investigation	YES
1959242	17786207	MR	PLoS5	Performed the experiments|Analyzed the data|Prepared the figures|Contributed to paper writing	Analyzed the data	Analyzed the data	Formal analysis	YES
1959242	17786207	MR	PLoS5	Performed the experiments|Analyzed the data|Prepared the figures|Contributed to paper writing	Prepared the figures	-	Visualization	YES
1959242	17786207	MR	PLoS5	Performed the experiments|Analyzed the data|Prepared the figures|Contributed to paper writing	Contributed to paper writing	Wrote the paper	-	YES
1959242	17786207	NS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1959242	17786207	NS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1959242	17786207	RG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Contributed to paper writing	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1959242	17786207	RG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Contributed to paper writing	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1959242	17786207	RG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Contributed to paper writing	Contributed to paper writing	Wrote the paper	-	YES
1959242	17786207	SR	PLoS5	Performed the experiments|Analyzed the data|Prepared the figures|Contributed to paper writing	Performed the experiments	Performed the experiments	Investigation	YES
1959242	17786207	SR	PLoS5	Performed the experiments|Analyzed the data|Prepared the figures|Contributed to paper writing	Analyzed the data	Analyzed the data	Formal analysis	YES
1959242	17786207	SR	PLoS5	Performed the experiments|Analyzed the data|Prepared the figures|Contributed to paper writing	Prepared the figures	-	Visualization	YES
1959242	17786207	SR	PLoS5	Performed the experiments|Analyzed the data|Prepared the figures|Contributed to paper writing	Contributed to paper writing	Wrote the paper	-	YES
4416774	25933412	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Revised different versions of the manuscript including the final version|Data collection|Wrote the first version of the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416774	25933412	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Revised different versions of the manuscript including the final version|Data collection|Wrote the first version of the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416774	25933412	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Revised different versions of the manuscript including the final version|Data collection|Wrote the first version of the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416774	25933412	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Revised different versions of the manuscript including the final version|Data collection|Wrote the first version of the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416774	25933412	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Revised different versions of the manuscript including the final version|Data collection|Wrote the first version of the paper	Revised different versions of the manuscript including the final version	Wrote the paper	Writing - Review & Editing	YES
4416774	25933412	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Revised different versions of the manuscript including the final version|Data collection|Wrote the first version of the paper	Data collection	Performed the experiments	Investigation	YES
4416774	25933412	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Revised different versions of the manuscript including the final version|Data collection|Wrote the first version of the paper	Wrote the first version of the paper	Wrote the paper	Writing - Original Draft	YES
4416774	25933412	BB	PLoS5	Analyzed the data|Wrote the paper|Revised different versions of the manuscript including the final version|Wrote the first version of the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416774	25933412	BB	PLoS5	Analyzed the data|Wrote the paper|Revised different versions of the manuscript including the final version|Wrote the first version of the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416774	25933412	BB	PLoS5	Analyzed the data|Wrote the paper|Revised different versions of the manuscript including the final version|Wrote the first version of the paper	Revised different versions of the manuscript including the final version	Wrote the paper	Writing - Review & Editing	YES
4416774	25933412	BB	PLoS5	Analyzed the data|Wrote the paper|Revised different versions of the manuscript including the final version|Wrote the first version of the paper	Wrote the first version of the paper	Wrote the paper	Writing - Original Draft	YES
4416774	25933412	BG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Revised different versions of the manuscript including the final version|Wrote the first version of the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416774	25933412	BG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Revised different versions of the manuscript including the final version|Wrote the first version of the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416774	25933412	BG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Revised different versions of the manuscript including the final version|Wrote the first version of the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416774	25933412	BG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Revised different versions of the manuscript including the final version|Wrote the first version of the paper	Revised different versions of the manuscript including the final version	Wrote the paper	Writing - Review & Editing	YES
4416774	25933412	BG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Revised different versions of the manuscript including the final version|Wrote the first version of the paper	Wrote the first version of the paper	Wrote the paper	Writing - Original Draft	YES
4416774	25933412	DL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Revised different versions of the manuscript including the final version|Data collection|Wrote the first version of the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416774	25933412	DL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Revised different versions of the manuscript including the final version|Data collection|Wrote the first version of the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416774	25933412	DL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Revised different versions of the manuscript including the final version|Data collection|Wrote the first version of the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416774	25933412	DL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Revised different versions of the manuscript including the final version|Data collection|Wrote the first version of the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416774	25933412	DL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Revised different versions of the manuscript including the final version|Data collection|Wrote the first version of the paper	Revised different versions of the manuscript including the final version	Wrote the paper	Writing - Review & Editing	YES
4416774	25933412	DL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Revised different versions of the manuscript including the final version|Data collection|Wrote the first version of the paper	Data collection	Performed the experiments	Investigation	YES
4416774	25933412	DL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Revised different versions of the manuscript including the final version|Data collection|Wrote the first version of the paper	Wrote the first version of the paper	Wrote the paper	Writing - Original Draft	YES
4416774	25933412	EBL	PLoS5	Performed the experiments|Analyzed the data|Revised different versions of the manuscript including the final version|Data collection	Performed the experiments	Performed the experiments	Investigation	YES
4416774	25933412	EBL	PLoS5	Performed the experiments|Analyzed the data|Revised different versions of the manuscript including the final version|Data collection	Analyzed the data	Analyzed the data	Formal analysis	YES
4416774	25933412	EBL	PLoS5	Performed the experiments|Analyzed the data|Revised different versions of the manuscript including the final version|Data collection	Revised different versions of the manuscript including the final version	Wrote the paper	Writing - Review & Editing	YES
4416774	25933412	EBL	PLoS5	Performed the experiments|Analyzed the data|Revised different versions of the manuscript including the final version|Data collection	Data collection	Performed the experiments	Investigation	YES
4416774	25933412	LAN	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Revised different versions of the manuscript including the final version	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416774	25933412	LAN	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Revised different versions of the manuscript including the final version	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416774	25933412	LAN	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Revised different versions of the manuscript including the final version	Revised different versions of the manuscript including the final version	Wrote the paper	Writing - Review & Editing	YES
4416774	25933412	TGN	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Revised different versions of the manuscript including the final version	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416774	25933412	TGN	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Revised different versions of the manuscript including the final version	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416774	25933412	TGN	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Revised different versions of the manuscript including the final version	Revised different versions of the manuscript including the final version	Wrote the paper	Writing - Review & Editing	YES
4810820	26977067	A.Y.H.	2	wrote the run3dmorph software, performed the 2d and 3d data extraction, conducted all analyses and drafted the manuscript	wrote the run3dmorph software, performed the 2d and 3d data extraction, conducted all analyses and drafted the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Data curation|Formal analysis|Investigation|Software|Writing - Original Draft	YES
4810820	26977067	All authors	2	gave final approval for publication	gave final approval for publication	-	-	NO
4810820	26977067	L.E.E.	2	performed slide preparation and imaging for all core top and exemplar species data, participated in data quality control and helped with manuscript writing	performed slide preparation and imaging for all core top and exemplar species data, participated in data quality control and helped with manuscript writing	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Investigation|Validation|Visualization|Writing - Original Draft	YES
4810820	26977067	P.M.H.	2	conceived, designed and coordinated the study, led the specimen species identification and drafted the manuscript	conceived, designed and coordinated the study, led the specimen species identification and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Project administration|Writing - Original Draft	YES
6451242	30953522	KDM	4	The study was designed by|data were collected and analyzed by|data interpretation and manuscript preparation were undertaken by	The study was designed by	Conceived and designed the experiments	Methodology	YES
6451242	30953522	KDM	4	The study was designed by|data were collected and analyzed by|data interpretation and manuscript preparation were undertaken by	data were collected and analyzed by	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6451242	30953522	KDM	4	The study was designed by|data were collected and analyzed by|data interpretation and manuscript preparation were undertaken by	data interpretation and manuscript preparation were undertaken by	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6451242	30953522	KS	4	data were collected and analyzed by|data interpretation and manuscript preparation were undertaken by	data were collected and analyzed by	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6451242	30953522	KS	4	data were collected and analyzed by|data interpretation and manuscript preparation were undertaken by	data interpretation and manuscript preparation were undertaken by	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6451242	30953522	PMN	4	data interpretation and manuscript preparation were undertaken by	data interpretation and manuscript preparation were undertaken by	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5583138	28871435	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5583138	28871435	B-MW	PLoS52	conceived and designed the experiments|contributed to the interpretation of the data	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5583138	28871435	B-MW	PLoS52	conceived and designed the experiments|contributed to the interpretation of the data	contributed to the interpretation of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5583138	28871435	ES	PLoS52	conceived and designed the experiments|contributed to the acquisition of the data|contributed to the analysis of the data|contributed to the interpretation of the data	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5583138	28871435	ES	PLoS52	conceived and designed the experiments|contributed to the acquisition of the data|contributed to the analysis of the data|contributed to the interpretation of the data	contributed to the acquisition of the data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5583138	28871435	ES	PLoS52	conceived and designed the experiments|contributed to the acquisition of the data|contributed to the analysis of the data|contributed to the interpretation of the data	contributed to the analysis of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5583138	28871435	ES	PLoS52	conceived and designed the experiments|contributed to the acquisition of the data|contributed to the analysis of the data|contributed to the interpretation of the data	contributed to the interpretation of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5583138	28871435	FP	PLoS52	conceived and designed the experiments|contributed to the acquisition of the data|contributed to the analysis of the data|contributed to the interpretation of the data	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5583138	28871435	FP	PLoS52	conceived and designed the experiments|contributed to the acquisition of the data|contributed to the analysis of the data|contributed to the interpretation of the data	contributed to the acquisition of the data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5583138	28871435	FP	PLoS52	conceived and designed the experiments|contributed to the acquisition of the data|contributed to the analysis of the data|contributed to the interpretation of the data	contributed to the analysis of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5583138	28871435	FP	PLoS52	conceived and designed the experiments|contributed to the acquisition of the data|contributed to the analysis of the data|contributed to the interpretation of the data	contributed to the interpretation of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5583138	28871435	MH	PLoS52	contributed to the interpretation of the data	contributed to the interpretation of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5583138	28871435	OM	PLoS52	contributed to the interpretation of the data	contributed to the interpretation of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5583138	28871435	RL	PLoS52	contributed to the acquisition of the data|contributed to the analysis of the data|contributed to the interpretation of the data	contributed to the acquisition of the data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5583138	28871435	RL	PLoS52	contributed to the acquisition of the data|contributed to the analysis of the data|contributed to the interpretation of the data	contributed to the analysis of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5583138	28871435	RL	PLoS52	contributed to the acquisition of the data|contributed to the analysis of the data|contributed to the interpretation of the data	contributed to the interpretation of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5799272	29449848	AA	2	constructed the expression vectors|analyzed fluorescent protein expression	constructed the expression vectors	Performed the experiments	Investigation	YES
5799272	29449848	AA	2	constructed the expression vectors|analyzed fluorescent protein expression	analyzed fluorescent protein expression	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5799272	29449848	DS-D	2	performed microscopy analysis of samples	performed microscopy analysis of samples	Performed the experiments	Investigation	YES
5799272	29449848	JJ	2	analyzed fluorescent protein expression|performed plasmid stability experiments	analyzed fluorescent protein expression	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5799272	29449848	JJ	2	analyzed fluorescent protein expression|performed plasmid stability experiments	performed plasmid stability experiments	Performed the experiments	Investigation	YES
5799272	29449848	KK	2	conceived the experiments	conceived the experiments	Conceived and designed the experiments	Conceptualization	YES
5799272	29449848	MB	2	constructed the expression vectors|analyzed fluorescent protein expression	constructed the expression vectors	Performed the experiments	Investigation	YES
5799272	29449848	MB	2	constructed the expression vectors|analyzed fluorescent protein expression	analyzed fluorescent protein expression	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5799272	29449848	RW	2	conceived the experiments|constructed the expression vectors|analyzed fluorescent protein expression|designed and executed the root seedling colonization experiments|wrote the paper draft	conceived the experiments	Conceived and designed the experiments	Conceptualization	YES
5799272	29449848	RW	2	conceived the experiments|constructed the expression vectors|analyzed fluorescent protein expression|designed and executed the root seedling colonization experiments|wrote the paper draft	constructed the expression vectors	Performed the experiments	Investigation	YES
5799272	29449848	RW	2	conceived the experiments|constructed the expression vectors|analyzed fluorescent protein expression|designed and executed the root seedling colonization experiments|wrote the paper draft	analyzed fluorescent protein expression	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5799272	29449848	RW	2	conceived the experiments|constructed the expression vectors|analyzed fluorescent protein expression|designed and executed the root seedling colonization experiments|wrote the paper draft	designed and executed the root seedling colonization experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5799272	29449848	RW	2	conceived the experiments|constructed the expression vectors|analyzed fluorescent protein expression|designed and executed the root seedling colonization experiments|wrote the paper draft	wrote the paper draft	Wrote the paper	Writing - Original Draft	YES
5799272	29449848	SS	2	designed and executed the root seedling colonization experiments	designed and executed the root seedling colonization experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3884799	24453813	Jun Tian	2	contributed equally to this work	contributed equally to this work	-	-	NO
3884799	24453813	Xiaobin Zeng	2	contributed equally to this work	contributed equally to this work	-	-	NO
4416776	25933021	SPD	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4416776	25933021	SPD	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4416776	25933021	SPD	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416776	25933021	WHS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416776	25933021	WHS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416776	25933021	WHS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416776	25933021	WHS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416776	25933021	WYH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416776	25933021	WYH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4416776	25933021	WYH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4416776	25933021	WYH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416776	25933021	YCC	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4416776	25933021	YCC	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4416776	25933021	YCC	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5983214	29669863	JY	2	planed the experiments	planed the experiments	-	-	NO
5983214	29669863	KK	2	conducted the pla study in ramos and dg75 cells	conducted the pla study in ramos and dg75 cells	Performed the experiments	Investigation	YES
5983214	29669863	MB	2	conducted the pla study in b1-8f/d mb1creert2 mice	conducted the pla study in b1-8f/d mb1creert2 mice	Performed the experiments	Investigation	YES
5983214	29669863	MC	2	conducted the phosphor flow experiment	conducted the phosphor flow experiment	Performed the experiments	Investigation	YES
5983214	29669863	MR	2	planed the experiments	planed the experiments	-	-	NO
5983214	29669863	PCM	2	conducted the pla study in b1-8f/d mb1creert2 mice	conducted the pla study in b1-8f/d mb1creert2 mice	Performed the experiments	Investigation	YES
5983214	29669863	PJN	2	helped with statistic and bioinformatics	helped with statistic and bioinformatics	Analyzed the data	Formal analysis	YES
5983214	29669863	XH	2	planed the experiments	planed the experiments	-	-	NO
5740884	29268697	CKL	2	were responsible for generating and analyzed the transcriptomic and proteomic data	were responsible for generating and analyzed the transcriptomic and proteomic data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5740884	29268697	GB	2	carried out qrt pcr and fruit quality-related experiments	carried out qrt pcr and fruit quality-related experiments	Performed the experiments	Investigation	YES
5740884	29268697	HJ	2	carried out qrt pcr and fruit quality-related experiments	carried out qrt pcr and fruit quality-related experiments	Performed the experiments	Investigation	YES
5740884	29268697	HL	2	carried out qrt pcr and fruit quality-related experiments	carried out qrt pcr and fruit quality-related experiments	Performed the experiments	Investigation	YES
5740884	29268697	LHW	2	were responsible for generating and analyzed the transcriptomic and proteomic data	were responsible for generating and analyzed the transcriptomic and proteomic data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5740884	29268697	LJJ	2	proposed and supervised the research	proposed and supervised the research	Conceived and designed the experiments	Conceptualization|Supervision	YES
5740884	29268697	WJH	2	were responsible for generating and analyzed the transcriptomic and proteomic data|conceived this experimental design and drafted the manuscript	were responsible for generating and analyzed the transcriptomic and proteomic data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5740884	29268697	WJH	2	were responsible for generating and analyzed the transcriptomic and proteomic data|conceived this experimental design and drafted the manuscript	conceived this experimental design and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
4822425	27022072	D.W.L.	2	contributed to writing this review	contributed to writing this review	Wrote the paper	Writing - Review & Editing	YES
4822425	27022072	M.B.M.	2	contributed to writing this review	contributed to writing this review	Wrote the paper	Writing - Review & Editing	YES
6458642	30971276	AL	4	Statistical analyses were performed by|The manuscript was written by	Statistical analyses were performed by	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6458642	30971276	AL	4	Statistical analyses were performed by|The manuscript was written by	The manuscript was written by	Wrote the paper	Writing - Original Draft	YES
6458642	30971276	AP	4	Data were collected by|The manuscript was written by	Data were collected by	Performed the experiments	Investigation	YES
6458642	30971276	AP	4	Data were collected by|The manuscript was written by	The manuscript was written by	Wrote the paper	Writing - Original Draft	YES
6458642	30971276	CB	4	Statistical analyses were performed by|The manuscript was written by	Statistical analyses were performed by	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6458642	30971276	CB	4	Statistical analyses were performed by|The manuscript was written by	The manuscript was written by	Wrote the paper	Writing - Original Draft	YES
6458642	30971276	HP	4	Data were collected by|The manuscript was written by	Data were collected by	Performed the experiments	Investigation	YES
6458642	30971276	HP	4	Data were collected by|The manuscript was written by	The manuscript was written by	Wrote the paper	Writing - Original Draft	YES
6458642	30971276	MKR	4	The study was designed by|Statistical analyses were performed by|The manuscript was written by	The study was designed by	Conceived and designed the experiments	Methodology	YES
6458642	30971276	MKR	4	The study was designed by|Statistical analyses were performed by|The manuscript was written by	Statistical analyses were performed by	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6458642	30971276	MKR	4	The study was designed by|Statistical analyses were performed by|The manuscript was written by	The manuscript was written by	Wrote the paper	Writing - Original Draft	YES
6458642	30971276	MP	4	Data were collected by|The manuscript was written by	Data were collected by	Performed the experiments	Investigation	YES
6458642	30971276	MP	4	Data were collected by|The manuscript was written by	The manuscript was written by	Wrote the paper	Writing - Original Draft	YES
5585113	28875485	ATN	2	participated in interpretation of experiments and finishing of the manuscript	participated in interpretation of experiments and finishing of the manuscript	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5585113	28875485	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5585113	28875485	IP	2	constructed the promoter library	constructed the promoter library	Performed the experiments	Investigation	YES
5585113	28875485	KBF	2	conducted the experiments determining the optimal conditions for the enzyme	conducted the experiments determining the optimal conditions for the enzyme	Performed the experiments	Investigation	YES
5585113	28875485	SR	2	they drafted the manuscript|participated in interpretation of experiments and finishing of the manuscript	they drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5585113	28875485	SR	2	they drafted the manuscript|participated in interpretation of experiments and finishing of the manuscript	participated in interpretation of experiments and finishing of the manuscript	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5585113	28875485	TOJ	2	constructed the promoter library	constructed the promoter library	Performed the experiments	Investigation	YES
5585113	28875485	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5799278	29449856	AG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5799278	29449856	AG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
5799278	29449856	AG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5799278	29449856	BM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5799278	29449856	BM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
5799278	29449856	BM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5799278	29449856	BM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5799278	29449856	CR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5799278	29449856	CR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5799278	29449856	CR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5799278	29449856	JT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5799278	29449856	JT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
5799278	29449856	JT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5799278	29449856	JT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5799278	29449856	KH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5799278	29449856	KH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
5799278	29449856	KH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5799278	29449856	LD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5799278	29449856	LD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
5799278	29449856	LD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5799278	29449856	LD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5799278	29449856	MI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5799278	29449856	MI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
5799278	29449856	MI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5799278	29449856	MI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5799278	29449856	PD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5799278	29449856	PD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5799278	29449856	PD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5799278	29449856	VP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5799278	29449856	VP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
5799278	29449856	VP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416777	25932996	AA	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416777	25932996	AC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416777	25932996	FDG	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416777	25932996	FDG	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416777	25932996	GS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416777	25932996	GS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416777	25932996	GS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416777	25932996	GS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416777	25932996	HTL	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416777	25932996	HTL	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416777	25932996	IS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416777	25932996	IS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416777	25932996	JO	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416777	25932996	KS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4416777	25932996	KS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416777	25932996	MC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416777	25932996	PKD	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416777	25932996	SL	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416777	25932996	VJR	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
6270691	25006791	Dong-Hyun Shin	PLoS52	performed research and analyzed the data	performed research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270691	25006791	Hong-Kun Rim	PLoS52	designed research|performed research and analyzed the data|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
6270691	25006791	Hong-Kun Rim	PLoS52	designed research|performed research and analyzed the data|wrote the paper	performed research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270691	25006791	Hong-Kun Rim	PLoS52	designed research|performed research and analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270691	25006791	Jae Yeol Lee	PLoS52	designed research|performed research and analyzed the data|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
6270691	25006791	Jae Yeol Lee	PLoS52	designed research|performed research and analyzed the data|wrote the paper	performed research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270691	25006791	Jae Yeol Lee	PLoS52	designed research|performed research and analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270691	25006791	Jung-Hye Choi	PLoS52	performed research and analyzed the data	performed research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270691	25006791	Kyung-Sook Chung	PLoS52	designed research|performed research and analyzed the data	designed research	Conceived and designed the experiments	Methodology	YES
6270691	25006791	Kyung-Sook Chung	PLoS52	designed research|performed research and analyzed the data	performed research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270691	25006791	Kyung-Tae Lee	PLoS52	designed research|performed research and analyzed the data|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
6270691	25006791	Kyung-Tae Lee	PLoS52	designed research|performed research and analyzed the data|wrote the paper	performed research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270691	25006791	Kyung-Tae Lee	PLoS52	designed research|performed research and analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270691	25006791	Sehyeon Cho	PLoS52	performed research and analyzed the data	performed research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270691	25006791	Young-Wuk Cho	PLoS52	performed research and analyzed the data	performed research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5740926	29268714	AB	PLoS52	provided key resources and reagents	provided key resources and reagents	Contributed reagents/materials/analysis tools	Resources	YES
5740926	29268714	All authors	PLoS52	read and edited the manuscript	read and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5740926	29268714	CC	PLoS52	contributed to optimize chip-seq protocol	contributed to optimize chip-seq protocol	Conceived and designed the experiments	Methodology	YES
5740926	29268714	GF	PLoS52	provided key resources and reagents	provided key resources and reagents	Contributed reagents/materials/analysis tools	Resources	YES
5740926	29268714	JHL	PLoS52	conceived and designed the experiments|supervised the work|performed data analysis|contributed to optimize chip-seq protocol|wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5740926	29268714	JHL	PLoS52	conceived and designed the experiments|supervised the work|performed data analysis|contributed to optimize chip-seq protocol|wrote the manuscript	supervised the work	-	Supervision	YES
5740926	29268714	JHL	PLoS52	conceived and designed the experiments|supervised the work|performed data analysis|contributed to optimize chip-seq protocol|wrote the manuscript	performed data analysis	Analyzed the data	Formal analysis	YES
5740926	29268714	JHL	PLoS52	conceived and designed the experiments|supervised the work|performed data analysis|contributed to optimize chip-seq protocol|wrote the manuscript	contributed to optimize chip-seq protocol	Conceived and designed the experiments	Methodology	YES
5740926	29268714	JHL	PLoS52	conceived and designed the experiments|supervised the work|performed data analysis|contributed to optimize chip-seq protocol|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5740926	29268714	JZ	PLoS52	conceived and designed the experiments|conducted most of the experiments|performed data analysis|wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5740926	29268714	JZ	PLoS52	conceived and designed the experiments|conducted most of the experiments|performed data analysis|wrote the manuscript	conducted most of the experiments	Performed the experiments	Investigation	YES
5740926	29268714	JZ	PLoS52	conceived and designed the experiments|conducted most of the experiments|performed data analysis|wrote the manuscript	performed data analysis	Analyzed the data	Formal analysis	YES
5740926	29268714	JZ	PLoS52	conceived and designed the experiments|conducted most of the experiments|performed data analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5740926	29268714	KR	PLoS52	contributed to optimize chip-seq protocol	contributed to optimize chip-seq protocol	Conceived and designed the experiments	Methodology	YES
5740926	29268714	SL	PLoS52	contributed to optimize chip-seq protocol	contributed to optimize chip-seq protocol	Conceived and designed the experiments	Methodology	YES
5740926	29268714	TO	PLoS52	contributed to optimize chip-seq protocol|provided key resources and reagents	contributed to optimize chip-seq protocol	Conceived and designed the experiments	Methodology	YES
5740926	29268714	TO	PLoS52	contributed to optimize chip-seq protocol|provided key resources and reagents	provided key resources and reagents	Contributed reagents/materials/analysis tools	Resources	YES
5740926	29268714	ZY	PLoS52	performed data analysis	performed data analysis	Analyzed the data	Formal analysis	YES
5740926	29268714	ZZ	PLoS52	contributed to optimize chip-seq protocol	contributed to optimize chip-seq protocol	Conceived and designed the experiments	Methodology	YES
6466674	30987668	EO	2	conceived the study|participated in the design and coordination of the study|carried out the data collection and performed the statistical analysis|helped to draft the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
6466674	30987668	EO	2	conceived the study|participated in the design and coordination of the study|carried out the data collection and performed the statistical analysis|helped to draft the manuscript	participated in the design and coordination of the study	Conceived and designed the experiments	Methodology|Project administration	YES
6466674	30987668	EO	2	conceived the study|participated in the design and coordination of the study|carried out the data collection and performed the statistical analysis|helped to draft the manuscript	carried out the data collection and performed the statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6466674	30987668	EO	2	conceived the study|participated in the design and coordination of the study|carried out the data collection and performed the statistical analysis|helped to draft the manuscript	helped to draft the manuscript	Wrote the paper	Writing - Original Draft	YES
6466674	30987668	HU	2	carried out the data collection and performed the statistical analysis	carried out the data collection and performed the statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6466674	30987668	KY	2	conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
6466674	30987668	YT	2	participated in the design and coordination of the study|carried out the data collection and performed the statistical analysis|helped to draft the manuscript	participated in the design and coordination of the study	Conceived and designed the experiments	Methodology|Project administration	YES
6466674	30987668	YT	2	participated in the design and coordination of the study|carried out the data collection and performed the statistical analysis|helped to draft the manuscript	carried out the data collection and performed the statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6466674	30987668	YT	2	participated in the design and coordination of the study|carried out the data collection and performed the statistical analysis|helped to draft the manuscript	helped to draft the manuscript	Wrote the paper	Writing - Original Draft	YES
1959244	17849001	EG	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1959244	17849001	EG	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1959244	17849001	EG	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6003642	29764980	AAG	PLoS52	provided human patient biopsies	provided human patient biopsies	Performed the experiments	Investigation	YES
6003642	29764980	AGS	PLoS52	provided financial support and conceptual advice	provided financial support and conceptual advice	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
6003642	29764980	AM	PLoS52	conceived and supervised this study and provided financial support|wrote the paper	conceived and supervised this study and provided financial support	Conceived and designed the experiments	Conceptualization|Funding acquisition|Supervision	YES
6003642	29764980	AM	PLoS52	conceived and supervised this study and provided financial support|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6003642	29764980	All authors	PLoS52	commented on and edited the manuscript	commented on and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
6003642	29764980	CB	PLoS52	performed experiments	performed experiments	Performed the experiments	Investigation	YES
6003642	29764980	CK	PLoS52	provided financial support and conceptual advice	provided financial support and conceptual advice	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
6003642	29764980	ChiP	PLoS52	sequencing and data analysis	sequencing and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6003642	29764980	DS	PLoS52	designed experiments, analyzed data, and provided conceptual advice	designed experiments, analyzed data, and provided conceptual advice	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
6003642	29764980	DZ	PLoS52	performed experiments	performed experiments	Performed the experiments	Investigation	YES
6003642	29764980	EIP	PLoS52	designed and performed most of the experiments and analyzed data	designed and performed most of the experiments and analyzed data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
6003642	29764980	GC	PLoS52	provided financial support and conceptual advice	provided financial support and conceptual advice	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
6003642	29764980	GS	PLoS52	performed the bioinformatics analyses	performed the bioinformatics analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6003642	29764980	HA	PLoS52	designed and performed most of the experiments and analyzed data	designed and performed most of the experiments and analyzed data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
6003642	29764980	IM	PLoS52	performed experiments	performed experiments	Performed the experiments	Investigation	YES
6003642	29764980	JH	PLoS52	designed and performed most of the experiments and analyzed data	designed and performed most of the experiments and analyzed data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
6003642	29764980	K-LL	PLoS52	conceived and supervised this study and provided financial support	conceived and supervised this study and provided financial support	Conceived and designed the experiments	Conceptualization|Funding acquisition|Supervision	YES
6003642	29764980	LI	PLoS52	performed experiments	performed experiments	Performed the experiments	Investigation	YES
6003642	29764980	RG	PLoS52	provided financial support and conceptual advice	provided financial support and conceptual advice	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
6003642	29764980	RH	PLoS52	performed experiments	performed experiments	Performed the experiments	Investigation	YES
6003642	29764980	RJD	PLoS52	designed experiments, analyzed data, and provided conceptual advice	designed experiments, analyzed data, and provided conceptual advice	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
6003642	29764980	SK	PLoS52	provided human patient biopsies	provided human patient biopsies	Performed the experiments	Investigation	YES
6003642	29764980	SL	PLoS52	performed experiments	performed experiments	Performed the experiments	Investigation	YES
6003642	29764980	TB	PLoS52	performed experiments	performed experiments	Performed the experiments	Investigation	YES
6003642	29764980	TD	PLoS52	designed and performed most of the experiments and analyzed data	designed and performed most of the experiments and analyzed data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
6003642	29764980	TZ	PLoS52	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5589716	28884316	CR	1	Wrote the manuscript or contributed to the manuscript	Wrote the manuscript or contributed to the manuscript	Wrote the paper	Writing - Original Draft	YES
5589716	28884316	JH	1	Wrote the manuscript or contributed to the manuscript	Wrote the manuscript or contributed to the manuscript	Wrote the paper	Writing - Original Draft	YES
5589716	28884316	JL	1	Conducted experiments and performed data analysis|Wrote the manuscript or contributed to the manuscript	Conducted experiments and performed data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5589716	28884316	JL	1	Conducted experiments and performed data analysis|Wrote the manuscript or contributed to the manuscript	Wrote the manuscript or contributed to the manuscript	Wrote the paper	Writing - Original Draft	YES
5589716	28884316	XL	1	Conducted experiments and performed data analysis	Conducted experiments and performed data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5589716	28884316	XP	1	Conducted experiments and performed data analysis	Conducted experiments and performed data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5589716	28884316	YY	1	Participated in research design|Conducted experiments and performed data analysis|Wrote the manuscript or contributed to the manuscript	Participated in research design	Conceived and designed the experiments	-	YES
5589716	28884316	YY	1	Participated in research design|Conducted experiments and performed data analysis|Wrote the manuscript or contributed to the manuscript	Conducted experiments and performed data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5589716	28884316	YY	1	Participated in research design|Conducted experiments and performed data analysis|Wrote the manuscript or contributed to the manuscript	Wrote the manuscript or contributed to the manuscript	Wrote the paper	Writing - Original Draft	YES
5589716	28884316	ZZ	1	Participated in research design|Wrote the manuscript or contributed to the manuscript	Participated in research design	Conceived and designed the experiments	-	YES
5589716	28884316	ZZ	1	Participated in research design|Wrote the manuscript or contributed to the manuscript	Wrote the manuscript or contributed to the manuscript	Wrote the paper	Writing - Original Draft	YES
5799660	29449850	All authors	2	approved the final version of the manuscript	approved the final version of the manuscript	-	-	NO
4416778	25933254	AJ	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416778	25933254	JSV	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416778	25933254	LL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416778	25933254	LL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416778	25933254	LL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416778	25933254	LL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416778	25933254	LR	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416778	25933254	MA	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416778	25933254	MMM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416778	25933254	MRR	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416778	25933254	PAG	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4416778	25933254	PAG	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1959246	17786199	AK	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1959246	17786199	AK	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1959246	17786199	AR	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1959246	17786199	AR	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1959246	17786199	CH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1959246	17786199	CH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1959246	17786199	CH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1959246	17786199	CH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1959246	17786199	IG	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1959246	17786199	IG	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1959246	17786199	JH	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1959246	17786199	JH	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1959246	17786199	MK	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1959246	17786199	MK	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1959246	17786199	RK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1959246	17786199	RK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1959246	17786199	RK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1959246	17786199	RK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1959246	17786199	RK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1959246	17786199	VH	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1959246	17786199	VH	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1959246	17786199	WH	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1959246	17786199	WH	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1959246	17786199	WL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1959246	17786199	WL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1959246	17786199	WL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1959246	17786199	WL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416779	25933428	MAH	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416779	25933428	MAH	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416779	25933428	RAN	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416779	25933428	RAN	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416779	25933428	WM	PLoS5	Contributed to method implementation	Contributed to method implementation	Performed the experiments	Investigation	YES
4416779	25933428	XL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416779	25933428	XL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416779	25933428	XL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416779	25933428	XL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5595706	28900905	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5595706	28900905	CX	PLoS52	conceived and designed the experiments, performed the experiments, analyzed the data, wrote the paper, prepared figures and/or tables	conceived and designed the experiments, performed the experiments, analyzed the data, wrote the paper, prepared figures and/or tables	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Visualization|Writing - Original Draft	YES
5595706	28900905	LY	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5595706	28900905	The authors	PLoS52	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5595706	28900905	WG	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5595706	28900905	YP	PLoS52	conceived and designed the experiments, analyzed the data, contributed reagents/materials/analysis tools, wrote the paper, prepared figures and/or tables, reviewed drafts of the paper	conceived and designed the experiments, analyzed the data, contributed reagents/materials/analysis tools, wrote the paper, prepared figures and/or tables, reviewed drafts of the paper	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Methodology|Resources|Visualization|Writing - Original Draft|Writing - Review & Editing	YES
5595706	28900905	ZH	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5595706	28900905	ZZ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
4843605	27069044	The authors	2	made equal contributions to the writing of this paper	made equal contributions to the writing of this paper	Wrote the paper	Writing - Original Draft	YES
5741169	28583085	AF	2	initiated and designed the study, is responsible for the facility in which the study was conducted, and wrote the manuscript|developed gema program and conducted gema experiments	initiated and designed the study, is responsible for the facility in which the study was conducted, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Writing - Original Draft	YES
5741169	28583085	AF	2	initiated and designed the study, is responsible for the facility in which the study was conducted, and wrote the manuscript|developed gema program and conducted gema experiments	developed gema program and conducted gema experiments	Performed the experiments	Investigation|Software	YES
5741169	28583085	BK	2	performed data analysis	performed data analysis	Analyzed the data	Formal analysis	YES
5741169	28583085	JM	2	performed data analysis and contributed to debugging of perl scripts	performed data analysis and contributed to debugging of perl scripts	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Software	YES
5741169	28583085	LF	2	jointly supervised the study and contributed to writing and revision of the manuscript	jointly supervised the study and contributed to writing and revision of the manuscript	Wrote the paper	Supervision|Writing - Original Draft|Writing - Review & Editing	YES
5741169	28583085	PB	2	performed data analysis	performed data analysis	Analyzed the data	Formal analysis	YES
5741169	28583085	RD	2	developed all computer programs for haplotype characterization, conducted all the experiments, was responsible for data analysis, validation and debugging of perl scripts, and contributed to writing and revision of the manuscript	developed all computer programs for haplotype characterization, conducted all the experiments, was responsible for data analysis, validation and debugging of perl scripts, and contributed to writing and revision of the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Software|Validation|Writing - Original Draft|Writing - Review & Editing	YES
5741169	28583085	SC	2	performed data analysis	performed data analysis	Analyzed the data	Formal analysis	YES
5741169	28583085	SQ	2	developed gema program and conducted gema experiments	developed gema program and conducted gema experiments	Performed the experiments	Investigation|Software	YES
5741169	28583085	YY	2	performed data analysis and contributed to debugging of perl scripts	performed data analysis and contributed to debugging of perl scripts	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Software	YES
4633533	26579541	Ge Junbo	2	contributed equally to this work as co-last authors	contributed equally to this work as co-last authors	-	-	NO
4633533	26579541	Guo Xiaofang	2	contributed equally to this work as co-first authors	contributed equally to this work as co-first authors	-	-	NO
4633533	26579541	Liu Haibo	2	contributed equally to this work as co-first authors	contributed equally to this work as co-first authors	-	-	NO
4633533	26579541	Yu Wanjun	2	contributed equally to this work as co-last authors	contributed equally to this work as co-last authors	-	-	NO
6270692	25314607	H.Y.	PLoS52	designed research|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
6270692	25314607	H.Y.	PLoS52	designed research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270692	25314607	R.K.	PLoS52	performed research and analyzed the data	performed research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270692	25314607	T.K.	PLoS52	designed research|performed research and analyzed the data|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
6270692	25314607	T.K.	PLoS52	designed research|performed research and analyzed the data|wrote the paper	performed research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270692	25314607	T.K.	PLoS52	designed research|performed research and analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270692	25314607	Y.I.	PLoS52	performed research and analyzed the data	performed research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6466775	30987663	DB	2	assisted in the revision of the manuscript	assisted in the revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
6466775	30987663	JQ	2	who assisted with each step and completion of the manuscript	who assisted with each step and completion of the manuscript	-	-	NO
6466775	30987663	LY	2	who assisted with each step and completion of the manuscript	who assisted with each step and completion of the manuscript	-	-	NO
6466775	30987663	The authors	2	declare no conflict of interests with the current publication, and all authors approved the final version of the manuscript	declare no conflict of interests with the current publication, and all authors approved the final version of the manuscript	-	-	NO
6466775	30987663	WC	2	assisted in the completion of the manuscript	assisted in the completion of the manuscript	-	-	NO
6466775	30987663	ZH	2	assisted in the data collection and data interpretation	assisted in the data collection and data interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6003645	29789392	DGT	PLoS52	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
6003645	29789392	H-PC	PLoS52	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
6003645	29789392	JT	PLoS52	conceived and designed the experiments|designed the research|performed research|analyzed data|wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6003645	29789392	JT	PLoS52	conceived and designed the experiments|designed the research|performed research|analyzed data|wrote the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
6003645	29789392	JT	PLoS52	conceived and designed the experiments|designed the research|performed research|analyzed data|wrote the manuscript	performed research	Performed the experiments	Investigation	YES
6003645	29789392	JT	PLoS52	conceived and designed the experiments|designed the research|performed research|analyzed data|wrote the manuscript	analyzed data	Analyzed the data	Formal analysis	YES
6003645	29789392	JT	PLoS52	conceived and designed the experiments|designed the research|performed research|analyzed data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6003645	29789392	K-iT	PLoS52	conceived and designed the experiments|analyzed data	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6003645	29789392	K-iT	PLoS52	conceived and designed the experiments|analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
6003645	29789392	MDP	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
6003645	29789392	RDW	PLoS52	designed the research|analyzed data|wrote the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
6003645	29789392	RDW	PLoS52	designed the research|analyzed data|wrote the manuscript	analyzed data	Analyzed the data	Formal analysis	YES
6003645	29789392	RDW	PLoS52	designed the research|analyzed data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6003645	29789392	SB	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
1959247	17848993	BC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1959247	17848993	DG	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1959247	17848993	WW	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1959247	17848993	WW	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1959247	17848993	XL	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1959247	17848993	XL	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1959247	17848993	YS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1959247	17848993	YS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416780	25933390	CQX	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416780	25933390	CQX	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416780	25933390	CQX	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416780	25933390	HBH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416780	25933390	HBH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416780	25933390	HBH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416780	25933390	HBH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416780	25933390	JMP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416780	25933390	JMP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416780	25933390	JMP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416780	25933390	LL	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416780	25933390	LL	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416780	25933390	SJ	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4416780	25933390	SJ	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416780	25933390	XYZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5799661	29449854	FR	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5799661	29449854	HG	2	carried out most of the experiment, data analysis, and wrote the method section of the manuscript	carried out most of the experiment, data analysis, and wrote the method section of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5799661	29449854	LS	2	carried out most of the experiment, data analysis, and wrote the method section of the manuscript	carried out most of the experiment, data analysis, and wrote the method section of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5799661	29449854	PW	2	designed the study|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5799661	29449854	PW	2	designed the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5799661	29449854	QZ	2	finalized the figures and tables	finalized the figures and tables	-	Visualization	YES
5799661	29449854	XJ	2	carried out most of the experiment, data analysis, and wrote the method section of the manuscript	carried out most of the experiment, data analysis, and wrote the method section of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5799661	29449854	XW	2	carried out most of the experiment, data analysis, and wrote the method section of the manuscript	carried out most of the experiment, data analysis, and wrote the method section of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5799661	29449854	YL	2	finalized the figures and tables	finalized the figures and tables	-	Visualization	YES
5799661	29449854	YW	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
4843608	27069047	A.A.G.	2	designed the experiment, interpreted the results and wrote the manuscript	designed the experiment, interpreted the results and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4843608	27069047	A.R.F.	2	collected and analysed the data	collected and analysed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4843608	27069047	D.Y.T.	2	designed the experiment, interpreted the results and wrote the manuscript|collected and analysed the data	designed the experiment, interpreted the results and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4843608	27069047	D.Y.T.	2	designed the experiment, interpreted the results and wrote the manuscript|collected and analysed the data	collected and analysed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5597559	28905318	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5597559	28905318	BL	2	designed the research and polished the manuscript	designed the research and polished the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5597559	28905318	GL	2	designed the research and polished the manuscript	designed the research and polished the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5597559	28905318	WL	2	performed the research, analyzed data and wrote this manuscript	performed the research, analyzed data and wrote this manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5597559	28905318	XJ	2	performed the research, analyzed data and wrote this manuscript	performed the research, analyzed data and wrote this manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5597559	28905318	YW	2	performed the research, analyzed data and wrote this manuscript	performed the research, analyzed data and wrote this manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5741867	29273011	AS	2	performed the sampling, the gene expression study and the data management	performed the sampling, the gene expression study and the data management	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5741867	29273011	CN	2	provided the transcriptomic data set	provided the transcriptomic data set	Contributed reagents/materials/analysis tools	Resources	YES
5741867	29273011	CY	2	developed and performed all the statistics	developed and performed all the statistics	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5741867	29273011	DB	2	performed the transcriptomic related biology interpration|performed the sampling, the gene expression study and the data management	performed the transcriptomic related biology interpration	Performed the experiments	Investigation	YES
5741867	29273011	DB	2	performed the transcriptomic related biology interpration|performed the sampling, the gene expression study and the data management	performed the sampling, the gene expression study and the data management	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5741867	29273011	ET	2	developed and undertook the experimental design, performed experimentations and ensured the biological interpretation|ensured the experimental transcriptomic analysis|performed the transcriptomic related biology interpration|wrote the paper and supervised all experimentations	developed and undertook the experimental design, performed experimentations and ensured the biological interpretation	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5741867	29273011	ET	2	developed and undertook the experimental design, performed experimentations and ensured the biological interpretation|ensured the experimental transcriptomic analysis|performed the transcriptomic related biology interpration|wrote the paper and supervised all experimentations	ensured the experimental transcriptomic analysis	-	-	NO
5741867	29273011	ET	2	developed and undertook the experimental design, performed experimentations and ensured the biological interpretation|ensured the experimental transcriptomic analysis|performed the transcriptomic related biology interpration|wrote the paper and supervised all experimentations	performed the transcriptomic related biology interpration	Performed the experiments	Investigation	YES
5741867	29273011	ET	2	developed and undertook the experimental design, performed experimentations and ensured the biological interpretation|ensured the experimental transcriptomic analysis|performed the transcriptomic related biology interpration|wrote the paper and supervised all experimentations	wrote the paper and supervised all experimentations	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Original Draft	YES
5741867	29273011	LG	2	ensured the experimental transcriptomic analysis|performed the sampling, the gene expression study and the data management	ensured the experimental transcriptomic analysis	-	-	NO
5741867	29273011	LG	2	ensured the experimental transcriptomic analysis|performed the sampling, the gene expression study and the data management	performed the sampling, the gene expression study and the data management	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5741867	29273011	LL	2	ensured the experimental transcriptomic analysis|performed the transcriptomic related biology interpration	ensured the experimental transcriptomic analysis	-	-	NO
5741867	29273011	LL	2	ensured the experimental transcriptomic analysis|performed the transcriptomic related biology interpration	performed the transcriptomic related biology interpration	Performed the experiments	Investigation	YES
5741867	29273011	NVV	2	developed and performed all the statistics|wrote the paper and supervised all experimentations	developed and performed all the statistics	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5741867	29273011	NVV	2	developed and performed all the statistics|wrote the paper and supervised all experimentations	wrote the paper and supervised all experimentations	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Original Draft	YES
5741867	29273011	PM	2	developed and undertook the experimental design, performed experimentations and ensured the biological interpretation|wrote the paper and supervised all experimentations	developed and undertook the experimental design, performed experimentations and ensured the biological interpretation	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5741867	29273011	PM	2	developed and undertook the experimental design, performed experimentations and ensured the biological interpretation|wrote the paper and supervised all experimentations	wrote the paper and supervised all experimentations	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Original Draft	YES
5741867	29273011	VS	2	developed and performed all the statistics|performed the transcriptomic related biology interpration|wrote the paper and supervised all experimentations	developed and performed all the statistics	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5741867	29273011	VS	2	developed and performed all the statistics|performed the transcriptomic related biology interpration|wrote the paper and supervised all experimentations	performed the transcriptomic related biology interpration	Performed the experiments	Investigation	YES
5741867	29273011	VS	2	developed and performed all the statistics|performed the transcriptomic related biology interpration|wrote the paper and supervised all experimentations	wrote the paper and supervised all experimentations	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Original Draft	YES
5741867	29273011	YB	2	was responsible of the animal management	was responsible of the animal management	-	-	NO
5741867	29273011	YL	2	provided the transcriptomic data set	provided the transcriptomic data set	Contributed reagents/materials/analysis tools	Resources	YES
6472067	30999897	AW	2	performed subject testing and experimental sessions	performed subject testing and experimental sessions	Performed the experiments	Investigation	YES
6472067	30999897	BM	2	performed subject testing and experimental sessions	performed subject testing and experimental sessions	Performed the experiments	Investigation	YES
6472067	30999897	DS	2	performed subject testing and experimental sessions	performed subject testing and experimental sessions	Performed the experiments	Investigation	YES
6472067	30999897	MB	2	performed subject testing and experimental sessions	performed subject testing and experimental sessions	Performed the experiments	Investigation	YES
6472067	30999897	SA	2	analyzed and interpreted all data results	analyzed and interpreted all data results	Analyzed the data	Formal analysis	YES
6270693	25383753	Anna Stochmal	PLoS52	designed the research and participated in the data analysis	designed the research and participated in the data analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
6270693	25383753	Jerzy Zuchowski	PLoS52	designed the research and participated in the data analysis|purified the compounds, determined their antioxidant activity, and performed the remaining experiments|wrote the paper	designed the research and participated in the data analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
6270693	25383753	Jerzy Zuchowski	PLoS52	designed the research and participated in the data analysis|purified the compounds, determined their antioxidant activity, and performed the remaining experiments|wrote the paper	purified the compounds, determined their antioxidant activity, and performed the remaining experiments	Performed the experiments	Investigation	YES
6270693	25383753	Jerzy Zuchowski	PLoS52	designed the research and participated in the data analysis|purified the compounds, determined their antioxidant activity, and performed the remaining experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270693	25383753	Lukasz Pecio	PLoS52	performed uplc-ms and nmr analyses of samples, as well as elucidated structures of the purified compounds|wrote the paper	performed uplc-ms and nmr analyses of samples, as well as elucidated structures of the purified compounds	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270693	25383753	Lukasz Pecio	PLoS52	performed uplc-ms and nmr analyses of samples, as well as elucidated structures of the purified compounds|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4843611	27069050	C.B.	2	were involved in the studys conception and design|were involved in data analysis and interpretation|were involved in the drafting of the manuscript|were involved during the revision process	were involved in the studys conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4843611	27069050	C.B.	2	were involved in the studys conception and design|were involved in data analysis and interpretation|were involved in the drafting of the manuscript|were involved during the revision process	were involved in data analysis and interpretation	Analyzed the data	Formal analysis	YES
4843611	27069050	C.B.	2	were involved in the studys conception and design|were involved in data analysis and interpretation|were involved in the drafting of the manuscript|were involved during the revision process	were involved in the drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
4843611	27069050	C.B.	2	were involved in the studys conception and design|were involved in data analysis and interpretation|were involved in the drafting of the manuscript|were involved during the revision process	were involved during the revision process	Wrote the paper	Writing - Review & Editing	YES
4843611	27069050	I.B.	2	were involved in data collection|were involved in data analysis and interpretation	were involved in data collection	Performed the experiments	Investigation	YES
4843611	27069050	I.B.	2	were involved in data collection|were involved in data analysis and interpretation	were involved in data analysis and interpretation	Analyzed the data	Formal analysis	YES
4843611	27069050	K.V.	2	were involved in the studys conception and design	were involved in the studys conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4843611	27069050	L.S.	2	were involved in the studys conception and design|were involved in data analysis and interpretation|were involved in the drafting of the manuscript|were involved during the revision process	were involved in the studys conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4843611	27069050	L.S.	2	were involved in the studys conception and design|were involved in data analysis and interpretation|were involved in the drafting of the manuscript|were involved during the revision process	were involved in data analysis and interpretation	Analyzed the data	Formal analysis	YES
4843611	27069050	L.S.	2	were involved in the studys conception and design|were involved in data analysis and interpretation|were involved in the drafting of the manuscript|were involved during the revision process	were involved in the drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
4843611	27069050	L.S.	2	were involved in the studys conception and design|were involved in data analysis and interpretation|were involved in the drafting of the manuscript|were involved during the revision process	were involved during the revision process	Wrote the paper	Writing - Review & Editing	YES
4843611	27069050	T.L.	2	were involved in the studys conception and design|were involved in data collection|were involved in data analysis and interpretation|were involved in the drafting of the manuscript|were involved during the revision process	were involved in the studys conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4843611	27069050	T.L.	2	were involved in the studys conception and design|were involved in data collection|were involved in data analysis and interpretation|were involved in the drafting of the manuscript|were involved during the revision process	were involved in data collection	Performed the experiments	Investigation	YES
4843611	27069050	T.L.	2	were involved in the studys conception and design|were involved in data collection|were involved in data analysis and interpretation|were involved in the drafting of the manuscript|were involved during the revision process	were involved in data analysis and interpretation	Analyzed the data	Formal analysis	YES
4843611	27069050	T.L.	2	were involved in the studys conception and design|were involved in data collection|were involved in data analysis and interpretation|were involved in the drafting of the manuscript|were involved during the revision process	were involved in the drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
4843611	27069050	T.L.	2	were involved in the studys conception and design|were involved in data collection|were involved in data analysis and interpretation|were involved in the drafting of the manuscript|were involved during the revision process	were involved during the revision process	Wrote the paper	Writing - Review & Editing	YES
4843611	27069050	V.M.	2	were involved in the studys conception and design|were involved in data collection|were involved in data analysis and interpretation|were involved in the drafting of the manuscript|were involved during the revision process	were involved in the studys conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4843611	27069050	V.M.	2	were involved in the studys conception and design|were involved in data collection|were involved in data analysis and interpretation|were involved in the drafting of the manuscript|were involved during the revision process	were involved in data collection	Performed the experiments	Investigation	YES
4843611	27069050	V.M.	2	were involved in the studys conception and design|were involved in data collection|were involved in data analysis and interpretation|were involved in the drafting of the manuscript|were involved during the revision process	were involved in data analysis and interpretation	Analyzed the data	Formal analysis	YES
4843611	27069050	V.M.	2	were involved in the studys conception and design|were involved in data collection|were involved in data analysis and interpretation|were involved in the drafting of the manuscript|were involved during the revision process	were involved in the drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
4843611	27069050	V.M.	2	were involved in the studys conception and design|were involved in data collection|were involved in data analysis and interpretation|were involved in the drafting of the manuscript|were involved during the revision process	were involved during the revision process	Wrote the paper	Writing - Review & Editing	YES
6003659	29789389	ADR	2	provided intellectual input and tools	provided intellectual input and tools	Contributed reagents/materials/analysis tools	Resources	YES
6003659	29789389	AF	2	performed data analysis	performed data analysis	Analyzed the data	Formal analysis	YES
6003659	29789389	AH	2	performed most experiments|performed data analysis|designed experiments|wrote the manuscript with contributions from all authors	performed most experiments	Performed the experiments	Investigation	YES
6003659	29789389	AH	2	performed most experiments|performed data analysis|designed experiments|wrote the manuscript with contributions from all authors	performed data analysis	Analyzed the data	Formal analysis	YES
6003659	29789389	AH	2	performed most experiments|performed data analysis|designed experiments|wrote the manuscript with contributions from all authors	designed experiments	Conceived and designed the experiments	Methodology	YES
6003659	29789389	AH	2	performed most experiments|performed data analysis|designed experiments|wrote the manuscript with contributions from all authors	wrote the manuscript with contributions from all authors	Wrote the paper	Writing - Original Draft	YES
6003659	29789389	AR	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
6003659	29789389	BDD	2	performed proteomics experiments|performed data analysis	performed proteomics experiments	Performed the experiments	Investigation	YES
6003659	29789389	BDD	2	performed proteomics experiments|performed data analysis	performed data analysis	Analyzed the data	Formal analysis	YES
6003659	29789389	DRA	2	provided intellectual input and tools	provided intellectual input and tools	Contributed reagents/materials/analysis tools	Resources	YES
6003659	29789389	HL	2	provided intellectual input and tools	provided intellectual input and tools	Contributed reagents/materials/analysis tools	Resources	YES
6003659	29789389	IGG	2	provided intellectual input and tools	provided intellectual input and tools	Contributed reagents/materials/analysis tools	Resources	YES
6003659	29789389	JM	2	provided intellectual input and tools	provided intellectual input and tools	Contributed reagents/materials/analysis tools	Resources	YES
6003659	29789389	JP	2	performed proteomics experiments|performed data analysis	performed proteomics experiments	Performed the experiments	Investigation	YES
6003659	29789389	JP	2	performed proteomics experiments|performed data analysis	performed data analysis	Analyzed the data	Formal analysis	YES
6003659	29789389	MGG	2	performed data analysis|designed experiments|wrote the manuscript with contributions from all authors	performed data analysis	Analyzed the data	Formal analysis	YES
6003659	29789389	MGG	2	performed data analysis|designed experiments|wrote the manuscript with contributions from all authors	designed experiments	Conceived and designed the experiments	Methodology	YES
6003659	29789389	MGG	2	performed data analysis|designed experiments|wrote the manuscript with contributions from all authors	wrote the manuscript with contributions from all authors	Wrote the paper	Writing - Original Draft	YES
6003659	29789389	MT	2	performed data analysis|designed experiments|wrote the manuscript with contributions from all authors	performed data analysis	Analyzed the data	Formal analysis	YES
6003659	29789389	MT	2	performed data analysis|designed experiments|wrote the manuscript with contributions from all authors	designed experiments	Conceived and designed the experiments	Methodology	YES
6003659	29789389	MT	2	performed data analysis|designed experiments|wrote the manuscript with contributions from all authors	wrote the manuscript with contributions from all authors	Wrote the paper	Writing - Original Draft	YES
6003659	29789389	OB-G	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
6003659	29789389	PAL	2	provided intellectual input and tools	provided intellectual input and tools	Contributed reagents/materials/analysis tools	Resources	YES
6003659	29789389	PD	2	provided intellectual input and tools	provided intellectual input and tools	Contributed reagents/materials/analysis tools	Resources	YES
6003659	29789389	RF	2	provided intellectual input and tools	provided intellectual input and tools	Contributed reagents/materials/analysis tools	Resources	YES
6003659	29789389	SAC	2	provided intellectual input and tools	provided intellectual input and tools	Contributed reagents/materials/analysis tools	Resources	YES
6003659	29789389	SH	2	performed most experiments|performed data analysis|designed experiments|wrote the manuscript with contributions from all authors	performed most experiments	Performed the experiments	Investigation	YES
6003659	29789389	SH	2	performed most experiments|performed data analysis|designed experiments|wrote the manuscript with contributions from all authors	performed data analysis	Analyzed the data	Formal analysis	YES
6003659	29789389	SH	2	performed most experiments|performed data analysis|designed experiments|wrote the manuscript with contributions from all authors	designed experiments	Conceived and designed the experiments	Methodology	YES
6003659	29789389	SH	2	performed most experiments|performed data analysis|designed experiments|wrote the manuscript with contributions from all authors	wrote the manuscript with contributions from all authors	Wrote the paper	Writing - Original Draft	YES
5799662	29449855	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5799662	29449855	CL	2	provided substantial help in specific experiments	provided substantial help in specific experiments	Performed the experiments	Investigation	YES
5799662	29449855	H-ML	2	provided substantial help in specific experiments|wrote the article	provided substantial help in specific experiments	Performed the experiments	Investigation	YES
5799662	29449855	H-ML	2	provided substantial help in specific experiments|wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
5799662	29449855	J-SL	2	designed the research|created transgenic plants overexpressing mir160 and target mimic|wrote the article	designed the research	Conceived and designed the experiments	Methodology	YES
5799662	29449855	J-SL	2	designed the research|created transgenic plants overexpressing mir160 and target mimic|wrote the article	created transgenic plants overexpressing mir160 and target mimic	Performed the experiments	Investigation	YES
5799662	29449855	J-SL	2	designed the research|created transgenic plants overexpressing mir160 and target mimic|wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
5799662	29449855	S-TJ	2	designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
5799662	29449855	STJ	2	wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
5799662	29449855	W-AT	2	created transgenic plants overexpressing mir160 and target mimic	created transgenic plants overexpressing mir160 and target mimic	Performed the experiments	Investigation	YES
5799662	29449855	Y-CK	2	provided substantial help in specific experiments	provided substantial help in specific experiments	Performed the experiments	Investigation	YES
5799662	29449855	Y-WK	2	provided substantial help in specific experiments	provided substantial help in specific experiments	Performed the experiments	Investigation	YES
1963315	17849007	AN	PLoS5	Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Wrote the paper|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1963315	17849007	AN	PLoS5	Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Wrote the paper|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1963315	17849007	AN	PLoS5	Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Wrote the paper|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1963315	17849007	AN	PLoS5	Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Wrote the paper|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1963315	17849007	AN	PLoS5	Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Wrote the paper|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1963315	17849007	AN	PLoS5	Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Wrote the paper|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1963315	17849007	AN	PLoS5	Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Wrote the paper|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1963315	17849007	CF	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1963315	17849007	DD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1963315	17849007	DD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1963315	17849007	DD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1963315	17849007	DD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1963315	17849007	HC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1963315	17849007	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1963315	17849007	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1963315	17849007	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1963315	17849007	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1963315	17849007	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1963315	17849007	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1963315	17849007	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1963315	17849007	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1963315	17849007	SM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416782	25933006	AB	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4416782	25933006	AB	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416782	25933006	DF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416782	25933006	DF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416782	25933006	DF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416782	25933006	GG	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416782	25933006	GG	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416782	25933006	JK	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416782	25933006	JL	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4416782	25933006	JL	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416782	25933006	MP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416782	25933006	MP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416782	25933006	MP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416782	25933006	MP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416782	25933006	RR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416782	25933006	RR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416782	25933006	RR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416782	25933006	RR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416782	25933006	RT	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416782	25933006	SA	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416782	25933006	VC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
3884964	24453924	Alberto Papi	2	contributed equally to this study	contributed equally to this study	-	-	NO
3884964	24453924	Silvano Pinamonti	2	contributed equally to this study	contributed equally to this study	-	-	NO
3167298	20558338	AH	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
3167298	20558338	BB	2	designed study and drafted paper	designed study and drafted paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3167298	20558338	IK	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
3167298	20558338	KK-S	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
3167298	20558338	MDud	2	analysed data	analysed data	Analyzed the data	Formal analysis	YES
3167298	20558338	MDur	2	analysed data and drafted a part of the paper	analysed data and drafted a part of the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3167298	20558338	MK	2	were responsible for the animal material and designed a part of the study	were responsible for the animal material and designed a part of the study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3167298	20558338	MS	2	were responsible for the animal material and designed a part of the study	were responsible for the animal material and designed a part of the study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5741891	29273013	AK	PLoS52	designed the experiment	designed the experiment	Conceived and designed the experiments	Methodology	YES
5741891	29273013	BS	PLoS52	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5741891	29273013	BZ	PLoS52	designed the experiment	designed the experiment	Conceived and designed the experiments	Methodology	YES
5741891	29273013	CA	PLoS52	designed the experiment	designed the experiment	Conceived and designed the experiments	Methodology	YES
5741891	29273013	ES	PLoS52	conceived the overall experiment plan	conceived the overall experiment plan	Conceived and designed the experiments	Conceptualization	YES
5741891	29273013	FP	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5741891	29273013	JR	PLoS52	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5741891	29273013	JY	PLoS52	performed experiments|analyzed the data	performed experiments	Performed the experiments	Investigation	YES
5741891	29273013	JY	PLoS52	performed experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5741891	29273013	JZ	PLoS52	designed the experiment	designed the experiment	Conceived and designed the experiments	Methodology	YES
5741891	29273013	KA	PLoS52	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5741891	29273013	KG	PLoS52	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5741891	29273013	MM	PLoS52	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5741891	29273013	NN	PLoS52	designed the experiment	designed the experiment	Conceived and designed the experiments	Methodology	YES
5741891	29273013	RS	PLoS52	designed the experiment	designed the experiment	Conceived and designed the experiments	Methodology	YES
5741891	29273013	SG	PLoS52	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5741891	29273013	SH	PLoS52	designed the experiment	designed the experiment	Conceived and designed the experiments	Methodology	YES
5741891	29273013	SS	PLoS52	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5741891	29273013	VA	PLoS52	designed the experiment	designed the experiment	Conceived and designed the experiments	Methodology	YES
5741891	29273013	VV	PLoS52	designed the experiment	designed the experiment	Conceived and designed the experiments	Methodology	YES
5741891	29273013	ZT	PLoS52	designed the experiment|analyzed the data	designed the experiment	Conceived and designed the experiments	Methodology	YES
5741891	29273013	ZT	PLoS52	designed the experiment|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5597562	28905332	All	PLoS52	persons and organizations that have contributed to the work presented in this article are authors and mentioned as such	persons and organizations that have contributed to the work presented in this article are authors and mentioned as such	-	-	NO
5597562	28905332	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5597562	28905332	Five Year	PLoS52	in dalian maritime university	in dalian maritime university	-	-	NO
5597562	28905332	JL	PLoS52	analyzed the as data	analyzed the as data	Analyzed the data	Formal analysis	YES
5597562	28905332	JZ	PLoS52	performed the experiments|acquired funding for the study	performed the experiments	Performed the experiments	Investigation	YES
5597562	28905332	JZ	PLoS52	performed the experiments|acquired funding for the study	acquired funding for the study	-	Funding acquisition	YES
5597562	28905332	QH	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5597562	28905332	SL	PLoS52	analyzed the as data|wrote the paper	analyzed the as data	Analyzed the data	Formal analysis	YES
5597562	28905332	SL	PLoS52	analyzed the as data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5597562	28905332	The authors	PLoS52	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5597562	28905332	WW	PLoS52	contributed to the experimental design	contributed to the experimental design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4416783	25933379	CT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416783	25933379	CT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416783	25933379	CT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416783	25933379	CT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416783	25933379	GB	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416783	25933379	GB	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416783	25933379	JC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416783	25933379	JC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416783	25933379	JC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416783	25933379	JC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416783	25933379	LDF	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416783	25933379	PBG	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4416783	25933379	PBG	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416783	25933379	RB	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416783	25933379	RB	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416783	25933379	SD	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4416783	25933379	SD	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416783	25933379	VC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4416783	25933379	VC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416783	25933379	ZY	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
6270694	24759074	D.X.	2	performed the ssr experiments and analyzed the data	performed the ssr experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270694	24759074	Q.X.Q.	2	collected plant materials	collected plant materials	Performed the experiments	Investigation	YES
6270694	24759074	W.L.H.	2	designed the experiments|performed the ssr experiments and analyzed the data	designed the experiments	Conceived and designed the experiments	Methodology	YES
6270694	24759074	W.L.H.	2	designed the experiments|performed the ssr experiments and analyzed the data	performed the ssr experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270694	24759074	W.X.	2	designed the experiments|performed the ssr experiments and analyzed the data|drafted this manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
6270694	24759074	W.X.	2	designed the experiments|performed the ssr experiments and analyzed the data|drafted this manuscript	performed the ssr experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270694	24759074	W.X.	2	designed the experiments|performed the ssr experiments and analyzed the data|drafted this manuscript	drafted this manuscript	Wrote the paper	Writing - Original Draft	YES
6270694	24759074	W.X.L.	2	performed the ssr experiments and analyzed the data	performed the ssr experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270694	24759074	Z.J.	2	performed the ssr experiments and analyzed the data	performed the ssr experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270694	24759074	Z.X.R.	2	designed the experiments|collected plant materials	designed the experiments	Conceived and designed the experiments	Methodology	YES
6270694	24759074	Z.X.R.	2	designed the experiments|collected plant materials	collected plant materials	Performed the experiments	Investigation	YES
6270694	24759074	Z.Y.X.	2	collected plant materials	collected plant materials	Performed the experiments	Investigation	YES
5799706	29449852	CT	2	conceived the study, designed the experiments, and modified the manuscript	conceived the study, designed the experiments, and modified the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
5799706	29449852	JHL	2	helped develop the hplc-esld method	helped develop the hplc-esld method	Performed the experiments	Investigation|Methodology	YES
5799706	29449852	JQ	2	coordinated the project	coordinated the project	-	Project administration	YES
5799706	29449852	JXL	2	contributed in pilot studies	contributed in pilot studies	-	-	NO
5799706	29449852	JZ	2	conducted most of the experiments and data analysis, and drafted the primary manuscript	conducted most of the experiments and data analysis, and drafted the primary manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5799706	29449852	XX	2	participated in gene expression analysis	participated in gene expression analysis	Performed the experiments	Investigation	YES
5799706	29449852	YF	2	participated in gene expression analysis	participated in gene expression analysis	Performed the experiments	Investigation	YES
4843612	27069051	Both authors	2	provided substantial contributions to conception and design, data analysis and interpretation|equally drafted and revised the article|have provided final approval of the version to be published	provided substantial contributions to conception and design, data analysis and interpretation	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Resources	YES
4843612	27069051	Both authors	2	provided substantial contributions to conception and design, data analysis and interpretation|equally drafted and revised the article|have provided final approval of the version to be published	equally drafted and revised the article	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4843612	27069051	Both authors	2	provided substantial contributions to conception and design, data analysis and interpretation|equally drafted and revised the article|have provided final approval of the version to be published	have provided final approval of the version to be published	-	-	NO
4843612	27069051	T.H.	2	created all new matlab scripts	created all new matlab scripts	Contributed reagents/materials/analysis tools	Software	YES
1963316	17849006	HW	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1963316	17849006	HW	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1963316	17849006	HW	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1963316	17849006	JM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1963316	17849006	JM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1963316	17849006	JM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1963316	17849006	JV	PLoS5	Initiated the work|Provided critical comments	Initiated the work	Conceived and designed the experiments	Conceptualization	YES
1963316	17849006	JV	PLoS5	Initiated the work|Provided critical comments	Provided critical comments	-	-	NO
6028026	29866703	AG	2	designed and performed quantitative pcr experiments	designed and performed quantitative pcr experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6028026	29866703	AMT	2	designed and performed human tissue co-culture experiments	designed and performed human tissue co-culture experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6028026	29866703	CES	2	designed and performed human tissue co-culture experiments	designed and performed human tissue co-culture experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6028026	29866703	CT	2	designed and performed human tissue co-culture experiments	designed and performed human tissue co-culture experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6028026	29866703	DBG	2	designed and performed zebrafish wounding, treatment and imaging experiments and mouse wound electron microscopy imaging|designed and performed human tissue co-culture experiments|wrote the manuscript	designed and performed zebrafish wounding, treatment and imaging experiments and mouse wound electron microscopy imaging	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Investigation|Methodology|Visualization	YES
6028026	29866703	DBG	2	designed and performed zebrafish wounding, treatment and imaging experiments and mouse wound electron microscopy imaging|designed and performed human tissue co-culture experiments|wrote the manuscript	designed and performed human tissue co-culture experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6028026	29866703	DBG	2	designed and performed zebrafish wounding, treatment and imaging experiments and mouse wound electron microscopy imaging|designed and performed human tissue co-culture experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6028026	29866703	HM	2	designed and performed human tissue co-culture experiments	designed and performed human tissue co-culture experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6028026	29866703	JC	2	designed and performed mouse wounding and multiphoton imaging experiments	designed and performed mouse wounding and multiphoton imaging experiments	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Investigation|Methodology|Visualization	YES
6028026	29866703	PM	2	supervised the project|wrote the manuscript	supervised the project	-	Supervision	YES
6028026	29866703	PM	2	supervised the project|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5741965	29272997	AEK	2	designed the rna seq component of the study|performed tissue collection, sample preparation and rna seq data generation|wrote the manuscript and created figures with significant comments and critical assessment by the other authors	designed the rna seq component of the study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5741965	29272997	AEK	2	designed the rna seq component of the study|performed tissue collection, sample preparation and rna seq data generation|wrote the manuscript and created figures with significant comments and critical assessment by the other authors	performed tissue collection, sample preparation and rna seq data generation	Performed the experiments	Investigation	YES
5741965	29272997	AEK	2	designed the rna seq component of the study|performed tissue collection, sample preparation and rna seq data generation|wrote the manuscript and created figures with significant comments and critical assessment by the other authors	wrote the manuscript and created figures with significant comments and critical assessment by the other authors	Wrote the paper	Visualization|Writing - Original Draft	YES
5741965	29272997	DDdS	2	determined high variability regions, low variability regions and unmappable regions	determined high variability regions, low variability regions and unmappable regions	-	-	NO
5741965	29272997	DMG	2	conceived and designed the study|did association analysis between diseases and genes and did the network analysis|wrote the manuscript and created figures with significant comments and critical assessment by the other authors	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5741965	29272997	DMG	2	conceived and designed the study|did association analysis between diseases and genes and did the network analysis|wrote the manuscript and created figures with significant comments and critical assessment by the other authors	did association analysis between diseases and genes and did the network analysis	Analyzed the data	Formal analysis	YES
5741965	29272997	DMG	2	conceived and designed the study|did association analysis between diseases and genes and did the network analysis|wrote the manuscript and created figures with significant comments and critical assessment by the other authors	wrote the manuscript and created figures with significant comments and critical assessment by the other authors	Wrote the paper	Visualization|Writing - Original Draft	YES
5741965	29272997	DT	2	conceived and designed the study|wrote the manuscript and created figures with significant comments and critical assessment by the other authors	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5741965	29272997	DT	2	conceived and designed the study|wrote the manuscript and created figures with significant comments and critical assessment by the other authors	wrote the manuscript and created figures with significant comments and critical assessment by the other authors	Wrote the paper	Visualization|Writing - Original Draft	YES
5741965	29272997	HVRs	2	did the functional analysis of them	did the functional analysis of them	-	-	NO
5741965	29272997	MCJM	2	performed tissue collection, sample preparation and rna seq data generation	performed tissue collection, sample preparation and rna seq data generation	Performed the experiments	Investigation	YES
5741965	29272997	PF	2	conceived and designed the study|wrote the manuscript and created figures with significant comments and critical assessment by the other authors	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5741965	29272997	PF	2	conceived and designed the study|wrote the manuscript and created figures with significant comments and critical assessment by the other authors	wrote the manuscript and created figures with significant comments and critical assessment by the other authors	Wrote the paper	Visualization|Writing - Original Draft	YES
4416786	25932627	MHU	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416786	25932627	MHU	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416786	25932627	MHU	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416786	25932627	MHU	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416786	25932627	MT	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416786	25932627	MT	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416786	25932627	MWS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416786	25932627	MWS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416786	25932627	MWS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416786	25932627	MWS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416786	25932627	MWS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416786	25932627	TT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416786	25932627	TT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416786	25932627	TT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416786	25932627	TT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416786	25932627	YH	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416786	25932627	YH	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416786	25932627	YU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416786	25932627	YU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416786	25932627	YU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416786	25932627	YU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416786	25932627	YU	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4633537	26579531	Denise Toscani	2	equally contributed to the paper	equally contributed to the paper	-	-	NO
4633537	26579531	Fabrizio Accardi	2	equally contributed to the paper	equally contributed to the paper	-	-	NO
5597564	28905320	All	2	relevant data are presented in the manuscript	relevant data are presented in the manuscript	-	-	NO
5597564	28905320	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5597564	28905320	BG	2	planned and carried out the experiments, analyzed the data and wrote the manuscript	planned and carried out the experiments, analyzed the data and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
5597564	28905320	CZ	2	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5597564	28905320	JN	2	participated in the data analysis	participated in the data analysis	Analyzed the data	Formal analysis	YES
5597564	28905320	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5597564	28905320	Yuhai Zhao	2	for excellent technical assistance	for excellent technical assistance	Performed the experiments	Investigation	YES
3167300	20558341	IHC	2	experiment, manuscript preparation and drafting	experiment, manuscript preparation and drafting	Wrote the paper	Writing - Original Draft	YES
3167300	20558341	LD	2	helped samples collection and pathological diagnosis	helped samples collection and pathological diagnosis	Performed the experiments	Investigation	YES
3167300	20558341	XC	2	helped samples collection and pathological diagnosis	helped samples collection and pathological diagnosis	Performed the experiments	Investigation	YES
4843613	27069052	A.W.	PLoS52	wrote the paper|contributed equally to this work	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4843613	27069052	A.W.	PLoS52	wrote the paper|contributed equally to this work	contributed equally to this work	-	-	NO
4843613	27069052	G.C.	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4843613	27069052	T.C.	PLoS52	wrote the paper|contributed equally to this work	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4843613	27069052	T.C.	PLoS52	wrote the paper|contributed equally to this work	contributed equally to this work	-	-	NO
5799827	29449851	AF	7	design of the work	design of the work	Conceived and designed the experiments	-	YES
5799827	29449851	JF	7	acquisition of data and design of the work	acquisition of data and design of the work	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5799827	29449851	RK	7	conception and design of the work; acquisition, analysis, and interpretation of data; writing the manuscript	conception and design of the work; acquisition, analysis, and interpretation of data; writing the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
5799827	29449851	VS-R	7	acquisition, analysis, and interpretation of data; writing the manuscript	acquisition, analysis, and interpretation of data; writing the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6028027	29871889	AGB	2	carried out experiments	carried out experiments	Performed the experiments	Investigation	YES
6028027	29871889	AWS	2	supervised bioinformatics analysis	supervised bioinformatics analysis	-	Formal analysis|Supervision	YES
6028027	29871889	BGH	2	provided reagents and intellectual input	provided reagents and intellectual input	Contributed reagents/materials/analysis tools	Resources	YES
6028027	29871889	BKD	2	carried out experiments	carried out experiments	Performed the experiments	Investigation	YES
6028027	29871889	CAP	2	carried out experiments	carried out experiments	Performed the experiments	Investigation	YES
6028027	29871889	CPB	2	provided reagents and intellectual input	provided reagents and intellectual input	Contributed reagents/materials/analysis tools	Resources	YES
6028027	29871889	DL	2	carried out experiments	carried out experiments	Performed the experiments	Investigation	YES
6028027	29871889	DML	2	carried out bioinformatics analysis	carried out bioinformatics analysis	Performed the experiments	Formal analysis|Investigation	YES
6028027	29871889	DPN	2	carried out experiments	carried out experiments	Performed the experiments	Investigation	YES
6028027	29871889	GJG	2	designed the study|supervised the study and wrote the manuscript, with input from the other authors	designed the study	Conceived and designed the experiments	Methodology	YES
6028027	29871889	GJG	2	designed the study|supervised the study and wrote the manuscript, with input from the other authors	supervised the study and wrote the manuscript, with input from the other authors	Wrote the paper	Supervision|Writing - Original Draft	YES
6028027	29871889	JT	2	carried out bioinformatics analysis	carried out bioinformatics analysis	Performed the experiments	Formal analysis|Investigation	YES
6028027	29871889	KAP	2	carried out bioinformatics analysis	carried out bioinformatics analysis	Performed the experiments	Formal analysis|Investigation	YES
6028027	29871889	LAS	2	carried out bioinformatics analysis|provided reagents and intellectual input	carried out bioinformatics analysis	Performed the experiments	Formal analysis|Investigation	YES
6028027	29871889	LAS	2	carried out bioinformatics analysis|provided reagents and intellectual input	provided reagents and intellectual input	Contributed reagents/materials/analysis tools	Resources	YES
6028027	29871889	NS	2	provided reagents and intellectual input	provided reagents and intellectual input	Contributed reagents/materials/analysis tools	Resources	YES
6028027	29871889	PAG	2	designed the study|carried out experiments|supervised the study and wrote the manuscript, with input from the other authors	designed the study	Conceived and designed the experiments	Methodology	YES
6028027	29871889	PAG	2	designed the study|carried out experiments|supervised the study and wrote the manuscript, with input from the other authors	carried out experiments	Performed the experiments	Investigation	YES
6028027	29871889	PAG	2	designed the study|carried out experiments|supervised the study and wrote the manuscript, with input from the other authors	supervised the study and wrote the manuscript, with input from the other authors	Wrote the paper	Supervision|Writing - Original Draft	YES
6028027	29871889	RL	2	carried out experiments	carried out experiments	Performed the experiments	Investigation	YES
6028027	29871889	SJC	2	carried out experiments	carried out experiments	Performed the experiments	Investigation	YES
6028027	29871889	SR	2	carried out experiments	carried out experiments	Performed the experiments	Investigation	YES
6028027	29871889	WDT	2	provided reagents and intellectual input	provided reagents and intellectual input	Contributed reagents/materials/analysis tools	Resources	YES
6028027	29871889	XL	2	carried out experiments	carried out experiments	Performed the experiments	Investigation	YES
6028027	29871889	YK-G	2	provided reagents and intellectual input	provided reagents and intellectual input	Contributed reagents/materials/analysis tools	Resources	YES
4416787	25933138	GH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4416787	25933138	GH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4416787	25933138	GH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416787	25933138	HZ	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416787	25933138	HZ	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416787	25933138	JH	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416787	25933138	JL	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416787	25933138	JW	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4416787	25933138	JW	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416787	25933138	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416787	25933138	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416787	25933138	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416787	25933138	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416787	25933138	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416787	25933138	SR	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416787	25933138	SR	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416787	25933138	TS	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416787	25933138	TS	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4416787	25933138	TS	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416787	25933138	XT	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4416787	25933138	XT	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1963317	17849022	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1963317	17849022	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1963317	17849022	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1963317	17849022	RH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1963317	17849022	RH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1963317	17849022	RH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1963317	17849022	RH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1963317	17849022	RL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1963317	17849022	RL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1963317	17849022	RL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1963317	17849022	SF	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Contributed to the discussion|Helped edit the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
1963317	17849022	SF	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Contributed to the discussion|Helped edit the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1963317	17849022	SF	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Contributed to the discussion|Helped edit the manuscript	Contributed to the discussion	-	-	NO
1963317	17849022	SF	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Contributed to the discussion|Helped edit the manuscript	Helped edit the manuscript	Wrote the paper	Writing - Review & Editing	YES
1963317	17849022	SJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1963317	17849022	SJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1963317	17849022	SJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1963317	17849022	VA	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Contributed to the discussion|Helped edit the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
1963317	17849022	VA	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Contributed to the discussion|Helped edit the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1963317	17849022	VA	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Contributed to the discussion|Helped edit the manuscript	Contributed to the discussion	-	-	NO
1963317	17849022	VA	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Contributed to the discussion|Helped edit the manuscript	Helped edit the manuscript	Wrote the paper	Writing - Review & Editing	YES
6270695	25225721	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6270695	25225721	B. Garg	2	was also responsible for the revisions and the proofs	was also responsible for the revisions and the proofs	Wrote the paper	Writing - Review & Editing	YES
6270695	25225721	C. Ling	2	were responsible for the subject of the review	were responsible for the subject of the review	-	-	NO
6270695	25225721	T. Bisht	2	performed bibliographic researches, participated in the discussions and also played an important role in preparing graphics or art work	performed bibliographic researches, participated in the discussions and also played an important role in preparing graphics or art work	Performed the experiments	Formal analysis|Investigation	YES
4633538	26579535	A. Heindl	4	Algorithm development was done by|Validation of the results was done by	Algorithm development was done by	Contributed reagents/materials/analysis tools	Software	YES
4633538	26579535	A. Heindl	4	Algorithm development was done by|Validation of the results was done by	Validation of the results was done by	Performed the experiments	Validation	YES
4633538	26579535	A. Seewald	4	Algorithm development was done by	Algorithm development was done by	Contributed reagents/materials/analysis tools	Software	YES
4633538	26579535	C. Smochina	4	Validation of the results was done by	Validation of the results was done by	Performed the experiments	Validation	YES
4633538	26579535	G. Bises	4	Section staining was optimized and performed by|Characterization of samples and highlighting of tumor areas were performed by|Entire project was designed and coordinated by	Section staining was optimized and performed by	Performed the experiments	Investigation	YES
4633538	26579535	G. Bises	4	Section staining was optimized and performed by|Characterization of samples and highlighting of tumor areas were performed by|Entire project was designed and coordinated by	Characterization of samples and highlighting of tumor areas were performed by	Performed the experiments	Investigation	YES
4633538	26579535	G. Bises	4	Section staining was optimized and performed by|Characterization of samples and highlighting of tumor areas were performed by|Entire project was designed and coordinated by	Entire project was designed and coordinated by	Conceived and designed the experiments	Methodology|Project administration	YES
4633538	26579535	I. Ellinger	4	Entire project was designed and coordinated by	Entire project was designed and coordinated by	Conceived and designed the experiments	Methodology|Project administration	YES
4633538	26579535	I. Mesteri	4	Pathological inspection and clinical data were provided by	Pathological inspection and clinical data were provided by	Performed the experiments	Investigation	YES
4633538	26579535	R. Rogojanu	4	Algorithm development was done by|Validation of the results was done by	Algorithm development was done by	Contributed reagents/materials/analysis tools	Software	YES
4633538	26579535	R. Rogojanu	4	Algorithm development was done by|Validation of the results was done by	Validation of the results was done by	Performed the experiments	Validation	YES
4633538	26579535	T. Thalhammer	4	Writing was coordinated by|Entire project was designed and coordinated by	Writing was coordinated by	Wrote the paper	Project administration	YES
4633538	26579535	T. Thalhammer	4	Writing was coordinated by|Entire project was designed and coordinated by	Entire project was designed and coordinated by	Conceived and designed the experiments	Methodology|Project administration	YES
4633538	26579535	U. Thiem	4	Section staining was optimized and performed by	Section staining was optimized and performed by	Performed the experiments	Investigation	YES
4843616	27069055	A.P.	2	wrote the initial storyline and argumentation, with later modifications by all three authors	wrote the initial storyline and argumentation, with later modifications by all three authors	Wrote the paper	Writing - Original Draft	YES
4843616	27069055	All authors	2	continually wrote, gave input and adapted the text throughout	continually wrote, gave input and adapted the text throughout	Wrote the paper	Writing - Original Draft	YES
4843616	27069055	H.D.J.	2	wrote the initial storyline and argumentation, with later modifications by all three authors|continually wrote, gave input and adapted the text throughout	wrote the initial storyline and argumentation, with later modifications by all three authors	Wrote the paper	Writing - Original Draft	YES
4843616	27069055	H.D.J.	2	wrote the initial storyline and argumentation, with later modifications by all three authors|continually wrote, gave input and adapted the text throughout	continually wrote, gave input and adapted the text throughout	Wrote the paper	Writing - Original Draft	YES
5745589	29281968	QL	2	conceived the study|conducted the experiments, analyzed data and drafted the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5745589	29281968	QL	2	conceived the study|conducted the experiments, analyzed data and drafted the manuscript	conducted the experiments, analyzed data and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5745589	29281968	RM	2	wrote custom python scripts and conducted differential expression analyses	wrote custom python scripts and conducted differential expression analyses	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Software|Writing - Original Draft	YES
5745589	29281968	TI	2	conceived the study|arranged samples and assisted in assembly and annotation of transcriptome data	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5745589	29281968	TI	2	conceived the study|arranged samples and assisted in assembly and annotation of transcriptome data	arranged samples and assisted in assembly and annotation of transcriptome data	Analyzed the data	Data curation|Formal analysis	YES
5745589	29281968	TK	2	assisted with mhc sequence and supertype analyses and contributed to drafting the manuscript	assisted with mhc sequence and supertype analyses and contributed to drafting the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5745589	29281968	YS	2	conceived the study|contributed to all evolutionary analyses and contributed to drafting the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5745589	29281968	YS	2	conceived the study|contributed to all evolutionary analyses and contributed to drafting the manuscript	contributed to all evolutionary analyses and contributed to drafting the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5799830	29449858	GW	PLoS52	wrote the paper|contributed in initial drafting of the manuscript, developing some of the figures, and have contributed equally	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5799830	29449858	GW	PLoS52	wrote the paper|contributed in initial drafting of the manuscript, developing some of the figures, and have contributed equally	contributed in initial drafting of the manuscript, developing some of the figures, and have contributed equally	Wrote the paper	Visualization|Writing - Original Draft	YES
5799830	29449858	HC	PLoS52	designated the experiment|wrote the paper	designated the experiment	Conceived and designed the experiments	Methodology	YES
5799830	29449858	HC	PLoS52	designated the experiment|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5799830	29449858	HZ	PLoS52	helped in drafting the manuscript	helped in drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
5799830	29449858	TL	PLoS52	helped in drafting the manuscript	helped in drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
5799830	29449858	XD	PLoS52	helped in drafting the manuscript	helped in drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
5799830	29449858	YX	PLoS52	contributed in initial drafting of the manuscript, developing some of the figures, and have contributed equally	contributed in initial drafting of the manuscript, developing some of the figures, and have contributed equally	Wrote the paper	Visualization|Writing - Original Draft	YES
6028031	29728368	AC	2	performed experiments|analyzed data	performed experiments	Performed the experiments	Investigation	YES
6028031	29728368	AC	2	performed experiments|analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
6028031	29728368	AM	2	performed experiments|analyzed data	performed experiments	Performed the experiments	Investigation	YES
6028031	29728368	AM	2	performed experiments|analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
6028031	29728368	BK	2	performed experiments|analyzed data	performed experiments	Performed the experiments	Investigation	YES
6028031	29728368	BK	2	performed experiments|analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
6028031	29728368	DK	2	performed experiments|analyzed data	performed experiments	Performed the experiments	Investigation	YES
6028031	29728368	DK	2	performed experiments|analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
6028031	29728368	EB	2	performed experiments|analyzed data	performed experiments	Performed the experiments	Investigation	YES
6028031	29728368	EB	2	performed experiments|analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
6028031	29728368	FH	2	analyzed data|supervised the project and wrote the manuscript, to which all authors contributed	analyzed data	Analyzed the data	Formal analysis	YES
6028031	29728368	FH	2	analyzed data|supervised the project and wrote the manuscript, to which all authors contributed	supervised the project and wrote the manuscript, to which all authors contributed	Wrote the paper	Supervision|Writing - Original Draft	YES
6028031	29728368	JJLH	2	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
6028031	29728368	RES	2	performed experiments|analyzed data	performed experiments	Performed the experiments	Investigation	YES
6028031	29728368	RES	2	performed experiments|analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
6028031	29728368	RS-N	2	analyzed data|supervised the project and wrote the manuscript, to which all authors contributed	analyzed data	Analyzed the data	Formal analysis	YES
6028031	29728368	RS-N	2	analyzed data|supervised the project and wrote the manuscript, to which all authors contributed	supervised the project and wrote the manuscript, to which all authors contributed	Wrote the paper	Supervision|Writing - Original Draft	YES
6028031	29728368	SMdS	2	performed experiments|analyzed data	performed experiments	Performed the experiments	Investigation	YES
6028031	29728368	SMdS	2	performed experiments|analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
6028031	29728368	ZNL	2	performed experiments|analyzed data	performed experiments	Performed the experiments	Investigation	YES
6028031	29728368	ZNL	2	performed experiments|analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5603465	28921475	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5603465	28921475	GS	2	participated in the data analysis	participated in the data analysis	Analyzed the data	Formal analysis	YES
5603465	28921475	QJ	2	participated in the data analysis	participated in the data analysis	Analyzed the data	Formal analysis	YES
5603465	28921475	SZ	2	planned and carried out the most experiments, analyzed the data and wrote the manuscript	planned and carried out the most experiments, analyzed the data and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
5603465	28921475	WD	2	reviewed and finalized the manuscript	reviewed and finalized the manuscript	Wrote the paper	Writing - Review & Editing	YES
5603465	28921475	XL	2	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
1963318	17849020	IM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1963318	17849020	IM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1963318	17849020	IM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1963318	17849020	IM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1963318	17849020	MI	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1963318	17849020	MI	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416788	25932647	HZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416788	25932647	HZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416788	25932647	HZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416788	25932647	HZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416788	25932647	LPB	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416788	25932647	LPB	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270696	24927368	Chin Chin Sieo	2	provided facilities and reviewed the manuscript	provided facilities and reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
6270696	24927368	Clemente Michael Vui	2	provided facilities and reviewed the manuscript	provided facilities and reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
6270696	24927368	Emilia Abdulmalek	2	contributed to the nmr analysis, and checking and confirming the structural identification	contributed to the nmr analysis, and checking and confirming the structural identification	Performed the experiments	Investigation	YES
6270696	24927368	Hui Yin Tan	2	participated in the experiments	participated in the experiments	Performed the experiments	Investigation	YES
6270696	24927368	Ling Wong	2	provided facilities and reviewed the manuscript	provided facilities and reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
6270696	24927368	Mookiah Saminathan	2	carried out the research and drafted the manuscript	carried out the research and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6270696	24927368	Norhani Abdullah	2	provided facilities and reviewed the manuscript	provided facilities and reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
6270696	24927368	Yin Wan Ho	2	designed the study, reviewed and edited the manuscript	designed the study, reviewed and edited the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
4843695	27114576	All the authors	2	contributed to the intellectual formulation of the manuscript and writing of the text, with each also providing a unique body of text reflecting their specific expertise	contributed to the intellectual formulation of the manuscript and writing of the text, with each also providing a unique body of text reflecting their specific expertise	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4843695	27114576	C.G.	2	produced the figures in the main text and electronic supplementary material	produced the figures in the main text and electronic supplementary material	-	Visualization	YES
4843695	27114576	G.W.	2	produced the figures in the main text and electronic supplementary material	produced the figures in the main text and electronic supplementary material	-	Visualization	YES
4843695	27114576	I.D.	2	produced the figures in the main text and electronic supplementary material	produced the figures in the main text and electronic supplementary material	-	Visualization	YES
4843695	27114576	N.B.	2	produced the figures in the main text and electronic supplementary material	produced the figures in the main text and electronic supplementary material	-	Visualization	YES
4843695	27114576	R.M.T.	2	produced the figures in the main text and electronic supplementary material	produced the figures in the main text and electronic supplementary material	-	Visualization	YES
4843695	27114576	S.P.	2	produced the figures in the main text and electronic supplementary material|produced the figures in the main text and electronic supplementary material|led the development of the theoretical and conceptual framework, including the mathematical modelling	produced the figures in the main text and electronic supplementary material	-	Visualization	YES
4843695	27114576	S.P.	2	produced the figures in the main text and electronic supplementary material|produced the figures in the main text and electronic supplementary material|led the development of the theoretical and conceptual framework, including the mathematical modelling	produced the figures in the main text and electronic supplementary material	-	Visualization	YES
4843695	27114576	S.P.	2	produced the figures in the main text and electronic supplementary material|produced the figures in the main text and electronic supplementary material|led the development of the theoretical and conceptual framework, including the mathematical modelling	led the development of the theoretical and conceptual framework, including the mathematical modelling	Conceived and designed the experiments|Performed the experiments	Conceptualization|Formal analysis|Methodology	YES
5799944	29449860	All authors	PLoS52	have read and approved the final manuscript	have read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5799944	29449860	C-TC	PLoS52	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5799944	29449860	J-DC	PLoS52	collected samples|analyzed data	collected samples	Performed the experiments	Investigation	YES
5799944	29449860	J-DC	PLoS52	collected samples|analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5799944	29449860	K-MS	PLoS52	collected samples|performed research|analyzed data|wrote the paper	collected samples	Performed the experiments	Investigation	YES
5799944	29449860	K-MS	PLoS52	collected samples|performed research|analyzed data|wrote the paper	performed research	Performed the experiments	Investigation	YES
5799944	29449860	K-MS	PLoS52	collected samples|performed research|analyzed data|wrote the paper	analyzed data	Analyzed the data	Formal analysis	YES
5799944	29449860	K-MS	PLoS52	collected samples|performed research|analyzed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5799944	29449860	S-YH	PLoS52	proposed, funded, and designed the research|collected samples|analyzed data|wrote the paper	proposed, funded, and designed the research	Conceived and designed the experiments	Conceptualization|Funding acquisition|Methodology	YES
5799944	29449860	S-YH	PLoS52	proposed, funded, and designed the research|collected samples|analyzed data|wrote the paper	collected samples	Performed the experiments	Investigation	YES
5799944	29449860	S-YH	PLoS52	proposed, funded, and designed the research|collected samples|analyzed data|wrote the paper	analyzed data	Analyzed the data	Formal analysis	YES
5799944	29449860	S-YH	PLoS52	proposed, funded, and designed the research|collected samples|analyzed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5799944	29449860	Y-CC	PLoS52	collected samples	collected samples	Performed the experiments	Investigation	YES
5745709	29281973	RAC	2	contributed to the conception and design of the study|collected and analyzed the data|wrote the manuscript	contributed to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5745709	29281973	RAC	2	contributed to the conception and design of the study|collected and analyzed the data|wrote the manuscript	collected and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5745709	29281973	RAC	2	contributed to the conception and design of the study|collected and analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5745709	29281973	RLM	2	contributed to the conception and design of the study|wrote the manuscript	contributed to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5745709	29281973	RLM	2	contributed to the conception and design of the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5049618	26220807	J.W.	2	carried out grafting experiments	carried out grafting experiments	Performed the experiments	Investigation	YES
5049618	26220807	L.Z.	2	carried out field experiments	carried out field experiments	Performed the experiments	Investigation	YES
5049618	26220807	Q.Y.	2	designed the experiment, supervised the study, and revised the manuscript	designed the experiment, supervised the study, and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Review & Editing	YES
5049618	26220807	W.Q.	2	carried out field experiments	carried out field experiments	Performed the experiments	Investigation	YES
5049618	26220807	X.M.Z.	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5049618	26220807	Y.C.	2	carried out field experiments	carried out field experiments	Performed the experiments	Investigation	YES
4416790	25932638	CFC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416790	25932638	CFC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416790	25932638	CYC	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4416790	25932638	CYC	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416790	25932638	HHC	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4416790	25932638	HHC	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416790	25932638	PCT	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416790	25932638	SHW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416790	25932638	SHW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416790	25932638	SHW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416790	25932638	SHW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416790	25932638	SYH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416790	25932638	SYH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416790	25932638	SYH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416790	25932638	YPL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416790	25932638	YPL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1963319	17849009	SJ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1963319	17849009	SJ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1963319	17849009	SJ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1963319	17849009	TK	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1963319	17849009	TK	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1963319	17849009	WI	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1963319	17849009	WI	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5603468	28921480	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5603468	28921480	FA	2	designed and worked on bench as well as drafted the manuscript	designed and worked on bench as well as drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Writing - Original Draft	YES
5603468	28921480	MBHN	2	developed hypothesis, supervised the work on bench and helped prepare the manuscript	developed hypothesis, supervised the work on bench and helped prepare the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Supervision|Writing - Original Draft	YES
5603468	28921480	MRED	2	developed hypothesis, supervised the work on bench and helped prepare the manuscript	developed hypothesis, supervised the work on bench and helped prepare the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Supervision|Writing - Original Draft	YES
6270697	25162956	Chang-Bao Li	2	contributed helpful discussion and scientific advice during the preparation of manuscript	contributed helpful discussion and scientific advice during the preparation of manuscript	Wrote the paper	Writing - Original Draft	YES
6270697	25162956	Jian Sun	2	conducted the experimental design|carried out the experiment and prepared the manuscript|revised and approved the final version of the manuscript	conducted the experimental design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6270697	25162956	Jian Sun	2	conducted the experimental design|carried out the experiment and prepared the manuscript|revised and approved the final version of the manuscript	carried out the experiment and prepared the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6270697	25162956	Jian Sun	2	conducted the experimental design|carried out the experiment and prepared the manuscript|revised and approved the final version of the manuscript	revised and approved the final version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
6270697	25162956	Li Li	2	revised and approved the final version of the manuscript	revised and approved the final version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
6270697	25162956	Mou-Ming Zhao	2	conducted the experimental design	conducted the experimental design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6270697	25162956	Xue-Mei He	2	carried out the experiment and prepared the manuscript	carried out the experiment and prepared the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6270697	25162956	Yi Dong	2	contributed helpful discussion and scientific advice during the preparation of manuscript	contributed helpful discussion and scientific advice during the preparation of manuscript	Wrote the paper	Writing - Original Draft	YES
6043850	29875129	ACR	2	designed experiments|performed experiments	designed experiments	Conceived and designed the experiments	Methodology	YES
6043850	29875129	ACR	2	designed experiments|performed experiments	performed experiments	Performed the experiments	Investigation	YES
6043850	29875129	JW	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
6043850	29875129	KM	2	conceived the project|designed experiments|performed experiments	conceived the project	Conceived and designed the experiments	Conceptualization	YES
6043850	29875129	KM	2	conceived the project|designed experiments|performed experiments	designed experiments	Conceived and designed the experiments	Methodology	YES
6043850	29875129	KM	2	conceived the project|designed experiments|performed experiments	performed experiments	Performed the experiments	Investigation	YES
6043850	29875129	KRL	2	designed experiments|performed experiments	designed experiments	Conceived and designed the experiments	Methodology	YES
6043850	29875129	KRL	2	designed experiments|performed experiments	performed experiments	Performed the experiments	Investigation	YES
6043850	29875129	SK	2	conceived the project	conceived the project	Conceived and designed the experiments	Conceptualization	YES
4633551	26579542	Carina Venter	2	did initial concept and final paper revision	did initial concept and final paper revision	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
4633551	26579542	Cheng-Han Wu	2	did statistical analysis and preparation of the paper	did statistical analysis and preparation of the paper	Analyzed the data	Formal analysis	YES
4633551	26579542	Efrem Eren	2	did data collection and final paper revision	did data collection and final paper revision	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4633551	26579542	Michael Ardern-Jones	2	did final paper revision and approval	did final paper revision and approval	Wrote the paper	Writing - Review & Editing	YES
4843696	27114577	A.K.	2	reviewed and approved the manuscript	reviewed and approved the manuscript	Wrote the paper	Writing - Review & Editing	YES
4843696	27114577	A.M.F.	2	reviewed and approved the manuscript	reviewed and approved the manuscript	Wrote the paper	Writing - Review & Editing	YES
4843696	27114577	A.T.	2	reviewed and approved the manuscript	reviewed and approved the manuscript	Wrote the paper	Writing - Review & Editing	YES
4843696	27114577	All authors	2	reviewed and approved the manuscript	reviewed and approved the manuscript	Wrote the paper	Writing - Review & Editing	YES
4843696	27114577	B.I.	2	reviewed and approved the manuscript	reviewed and approved the manuscript	Wrote the paper	Writing - Review & Editing	YES
4843696	27114577	B.W.	2	reviewed and approved the manuscript	reviewed and approved the manuscript	Wrote the paper	Writing - Review & Editing	YES
4843696	27114577	H.F.	2	reviewed and approved the manuscript	reviewed and approved the manuscript	Wrote the paper	Writing - Review & Editing	YES
4843696	27114577	H.K.	2	as senior authors|reviewed and approved the manuscript	as senior authors	-	-	NO
4843696	27114577	H.K.	2	as senior authors|reviewed and approved the manuscript	reviewed and approved the manuscript	Wrote the paper	Writing - Review & Editing	YES
4843696	27114577	I.Z.S.	2	reviewed and approved the manuscript	reviewed and approved the manuscript	Wrote the paper	Writing - Review & Editing	YES
4843696	27114577	K.W.	2	reviewed and approved the manuscript	reviewed and approved the manuscript	Wrote the paper	Writing - Review & Editing	YES
4843696	27114577	M.Q.	2	reviewed and approved the manuscript	reviewed and approved the manuscript	Wrote the paper	Writing - Review & Editing	YES
4843696	27114577	S.Sc	2	as senior authors|reviewed and approved the manuscript	as senior authors	-	-	NO
4843696	27114577	S.Sc	2	as senior authors|reviewed and approved the manuscript	reviewed and approved the manuscript	Wrote the paper	Writing - Review & Editing	YES
4843696	27114577	S.St	2	reviewed and approved the manuscript	reviewed and approved the manuscript	Wrote the paper	Writing - Review & Editing	YES
4843696	27114577	T.T.	2	reviewed and approved the manuscript	reviewed and approved the manuscript	Wrote the paper	Writing - Review & Editing	YES
4843696	27114577	W.L.	2	reviewed and approved the manuscript	reviewed and approved the manuscript	Wrote the paper	Writing - Review & Editing	YES
4843696	27114577	Y.C.	2	reviewed and approved the manuscript	reviewed and approved the manuscript	Wrote the paper	Writing - Review & Editing	YES
5745900	29281979	DAB	7	Experimental design, reviewed and edited paper	Experimental design, reviewed and edited paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5745900	29281979	HZ	7	Experimental design, reviewed and edited paper	Experimental design, reviewed and edited paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5745900	29281979	JCMD	7	Experimental design, reviewed and edited paper	Experimental design, reviewed and edited paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5745900	29281979	MSD	7	Collected samples, isolated rna, constructed cdna libraries, processed and analyzed rna seq data, wrote paper	Collected samples, isolated rna, constructed cdna libraries, processed and analyzed rna seq data, wrote paper	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Formal analysis|Investigation|Writing - Original Draft	YES
5745900	29281979	RAG	7	Experimental design, prepared viral isolate for inoculation, reviewed and edited paper	Experimental design, prepared viral isolate for inoculation, reviewed and edited paper	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5745900	29281979	SJL	7	Experimental design, reviewed and edited paper, oversaw analysis of data	Experimental design, reviewed and edited paper, oversaw analysis of data	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Supervision|Writing - Review & Editing	YES
4416791	25932636	AT	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416791	25932636	BR	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416791	25932636	CAA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416791	25932636	CAA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416791	25932636	CAA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416791	25932636	CAA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416791	25932636	CB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416791	25932636	DH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416791	25932636	MA	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4416791	25932636	MA	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416791	25932636	MS	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416791	25932636	MS	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416791	25932636	MW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416791	25932636	SB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416791	25932636	TA	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416791	25932636	TB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416791	25932636	TE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416791	25932636	TE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416791	25932636	TE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416791	25932636	TE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416791	25932636	TE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3167305	20558340	all authors	2	on this paper have been involved in substantial contributions to conception and design, acquisition of data, or analysis and interpretation of data	on this paper have been involved in substantial contributions to conception and design, acquisition of data, or analysis and interpretation of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
5603472	28921455	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5603472	28921455	CT	2	participated in the design and coordination of the study and in critically reviewing and revising the manuscript	participated in the design and coordination of the study and in critically reviewing and revising the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Review & Editing	YES
5603472	28921455	MG	2	carried out the immunoassays and drafted the manuscript|conceived of the study, participated in the design of the study and in reviewing and revising the manuscript	carried out the immunoassays and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5603472	28921455	MG	2	carried out the immunoassays and drafted the manuscript|conceived of the study, participated in the design of the study and in reviewing and revising the manuscript	conceived of the study, participated in the design of the study and in reviewing and revising the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
5603472	28921455	Military Medical Sciences	2	has engaged in studies regarding genetics, evolution and ecology of animal viruses and zoonotic viruses	has engaged in studies regarding genetics, evolution and ecology of animal viruses and zoonotic viruses	Performed the experiments	Investigation	YES
5603472	28921455	RCL	2	carried out the construction of the recombinant plasmid|is a lecturer concentrated on animal disease diagnosis and monitoring the prevalence of bacterial pathogens among animals	carried out the construction of the recombinant plasmid	Performed the experiments	Investigation	YES
5603472	28921455	RCL	2	carried out the construction of the recombinant plasmid|is a lecturer concentrated on animal disease diagnosis and monitoring the prevalence of bacterial pathogens among animals	is a lecturer concentrated on animal disease diagnosis and monitoring the prevalence of bacterial pathogens among animals	Performed the experiments	Investigation|Supervision	YES
5603472	28921455	TLQ	2	carried out the expression of protein	carried out the expression of protein	Performed the experiments	Investigation	YES
5603472	28921455	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5603472	28921455	WG	2	carried out the purification of the expressed protein	carried out the purification of the expressed protein	Performed the experiments	Investigation	YES
5603472	28921455	WJG	2	an associated professor, focuses on the prevention and control of classical swine fever	an associated professor, focuses on the prevention and control of classical swine fever	-	-	NO
5603472	28921455	XLY	2	conceived of the study, participated in the design of the study and in reviewing and revising the manuscript	conceived of the study, participated in the design of the study and in reviewing and revising the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
5054944	26178734	F.N.M.	2	performed gene, protein expression analysis and physiological analysis	performed gene, protein expression analysis and physiological analysis	Performed the experiments	Investigation	YES
5054944	26178734	H.L.	2	performed transgenic experiment and subcellular localization of proteins	performed transgenic experiment and subcellular localization of proteins	Performed the experiments	Investigation	YES
5054944	26178734	J.S.L.	2	performed gene, protein expression analysis and physiological analysis	performed gene, protein expression analysis and physiological analysis	Performed the experiments	Investigation	YES
5054944	26178734	J.Z.	2	designed the study, analyzed the data, and wrote the article|performed all the other studies	designed the study, analyzed the data, and wrote the article	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5054944	26178734	J.Z.	2	designed the study, analyzed the data, and wrote the article|performed all the other studies	performed all the other studies	Performed the experiments	Investigation	YES
5054944	26178734	S.W.Z.	2	designed the study, analyzed the data, and wrote the article	designed the study, analyzed the data, and wrote the article	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5054944	26178734	W.H.L.	2	assisted in physiological analysis	assisted in physiological analysis	-	-	NO
5054944	26178734	X.M.L.	2	assisted in physiological analysis	assisted in physiological analysis	-	-	NO
5054944	26178734	Z.Y.W.	2	designed the study, analyzed the data, and wrote the article	designed the study, analyzed the data, and wrote the article	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5054944	26178734	Z.Z.Z.	2	performed transgenic experiment and subcellular localization of proteins	performed transgenic experiment and subcellular localization of proteins	Performed the experiments	Investigation	YES
5800003	29449857	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
1963320	17849021	CS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1963320	17849021	CS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1963320	17849021	CS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1963320	17849021	JC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1963320	17849021	JC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1963320	17849021	JC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1963320	17849021	KF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1963320	17849021	KF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1963320	17849021	KF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1963320	17849021	KF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1963320	17849021	KF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416792	25932951	AD	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416792	25932951	AD	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416792	25932951	AD	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416792	25932951	AG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416792	25932951	AG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416792	25932951	AG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416792	25932951	AG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416792	25932951	AO	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416792	25932951	AO	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416792	25932951	CHM	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416792	25932951	CHM	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416792	25932951	LV	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416792	25932951	LV	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416792	25932951	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416792	25932951	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416792	25932951	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416792	25932951	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416792	25932951	RB	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416792	25932951	RB	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416792	25932951	SAAR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416792	25932951	SAAR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416792	25932951	SAAR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416792	25932951	SAAR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416792	25932951	SPN	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416792	25932951	SPN	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416792	25932951	SPN	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416792	25932951	TK	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416792	25932951	TK	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270698	24747648	All the authors	PLoS52	analyzed the data and discussed the results	analyzed the data and discussed the results	Analyzed the data	Formal analysis	YES
6270698	24747648	Guo-Rong Fan	PLoS52	conceived of this study and designed the experiments|helped with the drafted the manuscript with the	conceived of this study and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6270698	24747648	Guo-Rong Fan	PLoS52	conceived of this study and designed the experiments|helped with the drafted the manuscript with the	helped with the drafted the manuscript with the	Wrote the paper	Writing - Original Draft	YES
6270698	24747648	Ji Li	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
6270698	24747648	Jun Wen	PLoS52	conceived of this study and designed the experiments|performed the experiments|drafted the manuscript with the	conceived of this study and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6270698	24747648	Jun Wen	PLoS52	conceived of this study and designed the experiments|performed the experiments|drafted the manuscript with the	performed the experiments	Performed the experiments	Investigation	YES
6270698	24747648	Jun Wen	PLoS52	conceived of this study and designed the experiments|performed the experiments|drafted the manuscript with the	drafted the manuscript with the	Wrote the paper	Writing - Original Draft	YES
6270698	24747648	Wei-Qun Cao	PLoS52	conceived of this study and designed the experiments|performed the experiments	conceived of this study and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6270698	24747648	Wei-Qun Cao	PLoS52	conceived of this study and designed the experiments|performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
6270698	24747648	Wen-Ting Zhang	PLoS52	conceived of this study and designed the experiments|performed the experiments|drafted the manuscript with the	conceived of this study and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6270698	24747648	Wen-Ting Zhang	PLoS52	conceived of this study and designed the experiments|performed the experiments|drafted the manuscript with the	performed the experiments	Performed the experiments	Investigation	YES
6270698	24747648	Wen-Ting Zhang	PLoS52	conceived of this study and designed the experiments|performed the experiments|drafted the manuscript with the	drafted the manuscript with the	Wrote the paper	Writing - Original Draft	YES
4633690	26579544	Lufei Xiao	2	contributed equally to this work	contributed equally to this work	-	-	NO
4633690	26579544	Yingzhong Zhu	2	contributed equally to this work	contributed equally to this work	-	-	NO
4843698	27114579	A.H.	2	contributed experimental data	contributed experimental data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4843698	27114579	A.J.	2	contributed experimental data	contributed experimental data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4843698	27114579	A.S.	2	contributed experimental data	contributed experimental data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4843698	27114579	A.V.	2	contributed experimental data	contributed experimental data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4843698	27114579	B.S.	2	contributed experimental data	contributed experimental data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4843698	27114579	C.P.	2	contributed experimental data	contributed experimental data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4843698	27114579	D.C.	2	wrote the paper with input from all authors	wrote the paper with input from all authors	Wrote the paper	Writing - Original Draft	YES
4843698	27114579	D.T.	2	contributed experimental data	contributed experimental data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4843698	27114579	F.I.	2	conceived the project|wrote the paper with input from all authors	conceived the project	Conceived and designed the experiments	Conceptualization	YES
4843698	27114579	F.I.	2	conceived the project|wrote the paper with input from all authors	wrote the paper with input from all authors	Wrote the paper	Writing - Original Draft	YES
4843698	27114579	H.W.P.	2	contributed experimental data	contributed experimental data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4843698	27114579	J.K.	2	contributed experimental data	contributed experimental data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4843698	27114579	N.E.	2	conceived the project|wrote the paper with input from all authors	conceived the project	Conceived and designed the experiments	Conceptualization	YES
4843698	27114579	N.E.	2	conceived the project|wrote the paper with input from all authors	wrote the paper with input from all authors	Wrote the paper	Writing - Original Draft	YES
4843698	27114579	P.M.	2	wrote the paper with input from all authors	wrote the paper with input from all authors	Wrote the paper	Writing - Original Draft	YES
4843698	27114579	P.R.	2	contributed experimental data	contributed experimental data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4843698	27114579	V.L.	2	contributed experimental data	contributed experimental data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4843698	27114579	W.W.	2	developed the project during a workshop	developed the project during a workshop	-	-	NO
5745988	29281972	JH	2	carried out bioinformatics and analysis	carried out bioinformatics and analysis	Performed the experiments	Formal analysis|Investigation	YES
5745988	29281972	JSJ	2	conceived the study and wrote the manuscript	conceived the study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5745988	29281972	MCF	2	conceived the study and wrote the manuscript|performed lab work|carried out bioinformatics and analysis	conceived the study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5745988	29281972	MCF	2	conceived the study and wrote the manuscript|performed lab work|carried out bioinformatics and analysis	performed lab work	Performed the experiments	Investigation	YES
5745988	29281972	MCF	2	conceived the study and wrote the manuscript|performed lab work|carried out bioinformatics and analysis	carried out bioinformatics and analysis	Performed the experiments	Formal analysis|Investigation	YES
5745988	29281972	MU	2	conceived the study and wrote the manuscript|performed lab work	conceived the study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5745988	29281972	MU	2	conceived the study and wrote the manuscript|performed lab work	performed lab work	Performed the experiments	Investigation	YES
5745988	29281972	NRT	2	conceived the study and wrote the manuscript	conceived the study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5745988	29281972	SH	2	carried out bioinformatics and analysis	carried out bioinformatics and analysis	Performed the experiments	Formal analysis|Investigation	YES
5745988	29281972	SP	2	performed lab work	performed lab work	Performed the experiments	Investigation	YES
6043851	29752423	AD	2	planned, performed, and analyzed experiments|wrote the manuscript	planned, performed, and analyzed experiments	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation	YES
6043851	29752423	AD	2	planned, performed, and analyzed experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6043851	29752423	AM	2	planned, performed, and analyzed experiments|wrote the manuscript	planned, performed, and analyzed experiments	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation	YES
6043851	29752423	AM	2	planned, performed, and analyzed experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6043851	29752423	All authors	2	commented on the manuscript	commented on the manuscript	-	-	NO
6043851	29752423	DM	2	planned, performed, and analyzed experiments	planned, performed, and analyzed experiments	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation	YES
6043851	29752423	DZ	2	prepared transgenic lm strains and provided vb5 mice	prepared transgenic lm strains and provided vb5 mice	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
6043851	29752423	KDM	2	established and managed the germ-free strains	established and managed the germ-free strains	Performed the experiments	Investigation	YES
6043851	29752423	MH	2	planned, performed, and analyzed experiments	planned, performed, and analyzed experiments	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation	YES
6043851	29752423	MP	2	performed and analyzed experiments	performed and analyzed experiments	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6043851	29752423	OS	2	planned, performed, and analyzed experiments|conceived the study|wrote the manuscript	planned, performed, and analyzed experiments	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation	YES
6043851	29752423	OS	2	planned, performed, and analyzed experiments|conceived the study|wrote the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
6043851	29752423	OS	2	planned, performed, and analyzed experiments|conceived the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6043851	29752423	PD	2	analyzed experiments|wrote the manuscript	analyzed experiments	Analyzed the data	Formal analysis	YES
6043851	29752423	PD	2	analyzed experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6043851	29752423	RI	2	did the bioinformatic analysis of the rna sequencing data	did the bioinformatic analysis of the rna sequencing data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6043851	29752423	SO	2	prepared transgenic lm strains and provided vb5 mice	prepared transgenic lm strains and provided vb5 mice	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
6043851	29752423	VH	2	performed and analyzed experiments	performed and analyzed experiments	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5605482	28929383	AD	2	carried out bench work, data collection, results analysis and drafted the manuscript	carried out bench work, data collection, results analysis and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5605482	28929383	AM	2	advised for the overall study	advised for the overall study	-	-	NO
5605482	28929383	AS	2	carried out bench work, data collection and involved in manuscript preparation	carried out bench work, data collection and involved in manuscript preparation	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5605482	28929383	All	2	engaged for writing of the manuscript	engaged for writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5605482	28929383	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5605482	28929383	CG	2	designed and guided the experiments	designed and guided the experiments	Conceived and designed the experiments	Methodology|Supervision	YES
5605482	28929383	CS	2	advised for the overall study	advised for the overall study	-	-	NO
5605482	28929383	DW	2	selected and recruited the patient for the study	selected and recruited the patient for the study	Performed the experiments	Investigation	YES
5605482	28929383	MW	2	designed and guided the experiments	designed and guided the experiments	Conceived and designed the experiments	Methodology|Supervision	YES
5605482	28929383	NF	2	designed and guided the experiments	designed and guided the experiments	Conceived and designed the experiments	Methodology|Supervision	YES
5800298	29449849	JW	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5800298	29449849	KZ	PLoS52	wrote the manuscript|analyzed the data	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5800298	29449849	KZ	PLoS52	wrote the manuscript|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5800298	29449849	QZ	PLoS52	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5800298	29449849	SA	PLoS52	improved the manuscript	improved the manuscript	Wrote the paper	Writing - Review & Editing	YES
5800298	29449849	TC	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5800298	29449849	WY	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5800298	29449849	YZ	PLoS52	designed the experiments|completed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5800298	29449849	YZ	PLoS52	designed the experiments|completed the experiments	completed the experiments	Performed the experiments	Investigation	YES
5071735	26848539	C.X.	2	designed the study and analyzed data|wrote and revised the paper	designed the study and analyzed data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5071735	26848539	C.X.	2	designed the study and analyzed data|wrote and revised the paper	wrote and revised the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5071735	26848539	D.X.	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5071735	26848539	H.Y.	2	carried out transformation	carried out transformation	Performed the experiments	Investigation	YES
5071735	26848539	W.X.L.	2	performed data analysis	performed data analysis	Analyzed the data	Formal analysis	YES
5071735	26848539	Y.X.	2	performed data analysis|wrote and revised the paper	performed data analysis	Analyzed the data	Formal analysis	YES
5071735	26848539	Y.X.	2	performed data analysis|wrote and revised the paper	wrote and revised the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5071735	26848539	Z.C.	2	performed dna sequence variation analysis	performed dna sequence variation analysis	Performed the experiments	Investigation	YES
1964516	17849016	JT	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1964516	17849016	JT	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1964516	17849016	KH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1964516	17849016	KH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1964516	17849016	KH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1964516	17849016	RD	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1964516	17849016	RD	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1964516	17849016	RD	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1964516	17849016	TH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1964516	17849016	TH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1964516	17849016	TH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1964516	17849016	TH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1964516	17849016	TH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1964516	17849016	TR	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1964516	17849016	TR	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
3167306	20558343	INV	2	experimental design, acquisition, analysis and interpretation of data, drafting and critical review of the manuscript	experimental design, acquisition, analysis and interpretation of data, drafting and critical review of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
4633697	26579533	Jiawei Li	2	contributed equally to this work	contributed equally to this work	-	-	NO
4633697	26579533	Kosuke Endo	2	contributed equally to this work	contributed equally to this work	-	-	NO
4843700	27114581	All authors	2	discussed the results and contributed to the final version of the manuscript	discussed the results and contributed to the final version of the manuscript	-	-	NO
4843700	27114581	J.B.	2	coordinated the project and conducted frugivorous observations	coordinated the project and conducted frugivorous observations	Performed the experiments	Investigation|Project administration	YES
4843700	27114581	J.E.L.	2	performed field and laboratory work, and produced a first version of the manuscript|analysed the data and produced the figures	performed field and laboratory work, and produced a first version of the manuscript	Performed the experiments	Investigation	YES
4843700	27114581	J.E.L.	2	performed field and laboratory work, and produced a first version of the manuscript|analysed the data and produced the figures	analysed the data and produced the figures	Analyzed the data	Formal analysis|Visualization	YES
4843700	27114581	L.J.G.	2	analysed the data and produced the figures	analysed the data and produced the figures	Analyzed the data	Formal analysis|Visualization	YES
4843700	27114581	M.A.F.	2	performed the modularity analyses and network-related statistics	performed the modularity analyses and network-related statistics	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5746004	29281966	AZ	2	designed the study|carried out the data analysis	designed the study	Conceived and designed the experiments	Methodology	YES
5746004	29281966	AZ	2	designed the study|carried out the data analysis	carried out the data analysis	Analyzed the data	Formal analysis	YES
5746004	29281966	CF	2	performed illumina rna sequencing and reads processing	performed illumina rna sequencing and reads processing	Performed the experiments	Investigation	YES
5746004	29281966	CM	2	performed illumina rna sequencing and reads processing	performed illumina rna sequencing and reads processing	Performed the experiments	Investigation	YES
5746004	29281966	DvS	2	designed the study|provided the bacterial strain and coordinated the study|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5746004	29281966	DvS	2	designed the study|provided the bacterial strain and coordinated the study|wrote the manuscript	provided the bacterial strain and coordinated the study	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Project administration|Resources	YES
5746004	29281966	DvS	2	designed the study|provided the bacterial strain and coordinated the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5746004	29281966	FB	2	designed the study|carried out the data analysis|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5746004	29281966	FB	2	designed the study|carried out the data analysis|wrote the manuscript	carried out the data analysis	Analyzed the data	Formal analysis	YES
5746004	29281966	FB	2	designed the study|carried out the data analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5746004	29281966	GAL	2	performed illumina rna sequencing and reads processing	performed illumina rna sequencing and reads processing	Performed the experiments	Investigation	YES
5746004	29281966	ME	2	provided preliminary data	provided preliminary data	Contributed reagents/materials/analysis tools	Resources	YES
5746004	29281966	MV	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4416794	25933383	HS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416794	25933383	HS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416794	25933383	HS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416794	25933383	HS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416794	25933383	HS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416794	25933383	MOS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416794	25933383	MOS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416794	25933383	MOS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416794	25933383	MOS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416794	25933383	MOS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5801304	29456544	All authors	2	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
3885210	24453910	Each author	2	had participated sufficiently in the submission and will take public responsibility for the contents	had participated sufficiently in the submission and will take public responsibility for the contents	-	-	NO
6043852	29773570	AG	2	helped genetic manipulation and validation of the cell lines used in the current study	helped genetic manipulation and validation of the cell lines used in the current study	Performed the experiments	Investigation|Validation	YES
6043852	29773570	BL	2	designed and performed the metaphase cell staining and microscopy	designed and performed the metaphase cell staining and microscopy	Conceived and designed the experiments|Performed the experiments	Investigation	YES
6043852	29773570	BS	2	designed most of the experiments|contributed to manuscript preparation|supervised the entire project, designed and coordinated the experiments, and supervised manuscript preparation	designed most of the experiments	Conceived and designed the experiments	Methodology	YES
6043852	29773570	BS	2	designed most of the experiments|contributed to manuscript preparation|supervised the entire project, designed and coordinated the experiments, and supervised manuscript preparation	contributed to manuscript preparation	Wrote the paper	Writing - Original Draft	YES
6043852	29773570	BS	2	designed most of the experiments|contributed to manuscript preparation|supervised the entire project, designed and coordinated the experiments, and supervised manuscript preparation	supervised the entire project, designed and coordinated the experiments, and supervised manuscript preparation	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Supervision|Writing - Original Draft	YES
6043852	29773570	LZ	2	designed most of the experiments|contributed to manuscript preparation	designed most of the experiments	Conceived and designed the experiments	Methodology	YES
6043852	29773570	LZ	2	designed most of the experiments|contributed to manuscript preparation	contributed to manuscript preparation	Wrote the paper	Writing - Original Draft	YES
6043852	29773570	MZ	2	helped genetic manipulation and validation of the cell lines used in the current study	helped genetic manipulation and validation of the cell lines used in the current study	Performed the experiments	Investigation|Validation	YES
6043852	29773570	VWL	2	helped genetic manipulation and validation of the cell lines used in the current study	helped genetic manipulation and validation of the cell lines used in the current study	Performed the experiments	Investigation|Validation	YES
6043852	29773570	WJ	2	helped with the chromosomal segregation and other experiments	helped with the chromosomal segregation and other experiments	Performed the experiments	Investigation	YES
6043852	29773570	ZL	2	designed most of the experiments|conducted the majority of the experiments|contributed to manuscript preparation	designed most of the experiments	Conceived and designed the experiments	Methodology	YES
6043852	29773570	ZL	2	designed most of the experiments|conducted the majority of the experiments|contributed to manuscript preparation	conducted the majority of the experiments	Performed the experiments	Investigation	YES
6043852	29773570	ZL	2	designed most of the experiments|conducted the majority of the experiments|contributed to manuscript preparation	contributed to manuscript preparation	Wrote the paper	Writing - Original Draft	YES
6043852	29773570	ZS	2	designed and performed the metaphase cell staining and microscopy	designed and performed the metaphase cell staining and microscopy	Conceived and designed the experiments|Performed the experiments	Investigation	YES
6270699	24434672	Ariosvaldo Medeiros	2	contributed in the execution of field tests and interpretation of analysis	contributed in the execution of field tests and interpretation of analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270699	24434672	Ertha Medeiros	2	contributed in the data obtaining, analysis and interpretation and in the manuscript writing	contributed in the data obtaining, analysis and interpretation and in the manuscript writing	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
6270699	24434672	Marco Bomfim	2	contributed to the study design and data analysis	contributed to the study design and data analysis	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Methodology|Resources	YES
6270699	24434672	Maria Oliveira	2	contributed in the execution and interpretation of analysis	contributed in the execution and interpretation of analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270699	24434672	Marta Madruga	2	contributed to the study design, data analysis and manuscript writing	contributed to the study design, data analysis and manuscript writing	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Original Draft	YES
6270699	24434672	Mayara Sabedot	2	contributed in the execution of field tests and interpretation of analysis	contributed in the execution of field tests and interpretation of analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270699	24434672	Rita Queiroga	2	contributed in the data analysis and interpretation and also in the manuscript writing	contributed in the data analysis and interpretation and also in the manuscript writing	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
1964517	17849008	SA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1964517	17849008	SA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1964517	17849008	SA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1964517	17849008	SA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1964517	17849008	SA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5607059	28933031	ADN	2	carried out the experimental studies and participated in the experiments	carried out the experimental studies and participated in the experiments	Performed the experiments	Investigation	YES
5607059	28933031	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5607059	28933031	DA	2	carried out the experimental studies and participated in the experiments	carried out the experimental studies and participated in the experiments	Performed the experiments	Investigation	YES
5607059	28933031	HS	2	carried out the experimental studies and participated in the experiments|revised the molecular analysis	carried out the experimental studies and participated in the experiments	Performed the experiments	Investigation	YES
5607059	28933031	HS	2	carried out the experimental studies and participated in the experiments|revised the molecular analysis	revised the molecular analysis	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5607059	28933031	SM	2	revised the molecular analysis	revised the molecular analysis	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5607059	28933031	The authors	2	declare that they have no competing interests|alone are responsible for the content and writing of the manuscript	declare that they have no competing interests	-	-	NO
5607059	28933031	The authors	2	declare that they have no competing interests|alone are responsible for the content and writing of the manuscript	alone are responsible for the content and writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5947113	29205819	D.V.	2	supervised the study and revised the manuscript	supervised the study and revised the manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
4874388	27160593	All authors	2	reviewed and approved the final manuscript	reviewed and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5746007	29281970	All authors	2	edited and approved the manuscript	edited and approved the manuscript	Wrote the paper	Writing - Review & Editing	YES
5746007	29281970	JAD	2	designed, performed, and interpreted the experiments and wrote the manuscript	designed, performed, and interpreted the experiments and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5746007	29281970	JB	2	designed, performed, and interpreted the experiments and wrote the manuscript	designed, performed, and interpreted the experiments and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
6043855	29898893	All authors	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6043855	29898893	DJM	2	realized the conclusive figure	realized the conclusive figure	-	Visualization	YES
6043855	29898893	EM	2	realized the conclusive figure	realized the conclusive figure	-	Visualization	YES
6043855	29898893	MP	2	realized the conclusive figure	realized the conclusive figure	-	Visualization	YES
4416795	25933361	EH	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416795	25933361	EH	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416795	25933361	GB	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416795	25933361	GB	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416795	25933361	HR	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416795	25933361	HR	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416795	25933361	JL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416795	25933361	JL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416795	25933361	JL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416795	25933361	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416795	25933361	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416795	25933361	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416795	25933361	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5801407	29456546	All authors	2	helped designing the study, interpreting results, and reviewing the manuscript	helped designing the study, interpreting results, and reviewing the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
5801407	29456546	S. The	2	other authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	other authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	Performed the experiments	Investigation	YES
1964518	17848999	AZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1964518	17848999	AZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1964518	17848999	AZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1964518	17848999	AZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1964518	17848999	LP	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1964518	17848999	LP	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4874389	27160594	B.P.L.	2	conceived of, performed analysis for and wrote this article	conceived of, performed analysis for and wrote this article	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
4874389	27160594	R.L.U.	2	conceived of, performed analysis for and wrote this article	conceived of, performed analysis for and wrote this article	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
4416796	25933422	CP	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416796	25933422	JRK	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416796	25933422	RG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416796	25933422	RG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416796	25933422	RG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416796	25933422	RK	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416796	25933422	RK	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416796	25933422	RK	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416796	25933422	SS	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5608654	28936604	AH	PLoS52	designed the work that led to the manuscript|contributed in the interpretation of the results|wrote the paper	designed the work that led to the manuscript	Conceived and designed the experiments	-	YES
5608654	28936604	AH	PLoS52	designed the work that led to the manuscript|contributed in the interpretation of the results|wrote the paper	contributed in the interpretation of the results	Analyzed the data	Formal analysis	YES
5608654	28936604	AH	PLoS52	designed the work that led to the manuscript|contributed in the interpretation of the results|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5608654	28936604	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5608654	28936604	FTZ	PLoS52	produced and analyzed the experimental data|wrote the paper	produced and analyzed the experimental data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5608654	28936604	FTZ	PLoS52	produced and analyzed the experimental data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5608654	28936604	KCD	PLoS52	contributed in the interpretation of the results	contributed in the interpretation of the results	Analyzed the data	Formal analysis	YES
5608654	28936604	MGM	PLoS52	contributed in the interpretation of the results|wrote the paper	contributed in the interpretation of the results	Analyzed the data	Formal analysis	YES
5608654	28936604	MGM	PLoS52	contributed in the interpretation of the results|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5608654	28936604	MS	PLoS52	contributed in the interpretation of the results	contributed in the interpretation of the results	Analyzed the data	Formal analysis	YES
5608654	28936604	NAB	PLoS52	contributed in the interpretation of the results|wrote the paper	contributed in the interpretation of the results	Analyzed the data	Formal analysis	YES
5608654	28936604	NAB	PLoS52	contributed in the interpretation of the results|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5608654	28936604	NCB	PLoS52	produced and analyzed the experimental data|wrote the paper	produced and analyzed the experimental data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5608654	28936604	NCB	PLoS52	produced and analyzed the experimental data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5608654	28936604	The authors	PLoS52	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
6270701	25532835	B.P.	PLoS52	performed the experiments|contributed reagents/materials/analysis tools	performed the experiments	Performed the experiments	Investigation	YES
6270701	25532835	B.P.	PLoS52	performed the experiments|contributed reagents/materials/analysis tools	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
6270701	25532835	D.A.	PLoS52	conceived and designed the experiments|analyzed the data	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6270701	25532835	D.A.	PLoS52	conceived and designed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
6270701	25532835	H.J.	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
6270701	25532835	J.C.	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6270701	25532835	J.C.	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
6270701	25532835	J.C.	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
6270701	25532835	M.W.	PLoS52	conceived and designed the experiments|analyzed the data|contributed reagents/materials/analysis tools|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6270701	25532835	M.W.	PLoS52	conceived and designed the experiments|analyzed the data|contributed reagents/materials/analysis tools|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
6270701	25532835	M.W.	PLoS52	conceived and designed the experiments|analyzed the data|contributed reagents/materials/analysis tools|wrote the paper	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
6270701	25532835	M.W.	PLoS52	conceived and designed the experiments|analyzed the data|contributed reagents/materials/analysis tools|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270701	25532835	P.B.-A.	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
6270701	25532835	P.B.-A.	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5801417	29456542	T. The	2	four of them contributed to this editorial	four of them contributed to this editorial	-	-	NO
6043907	29880602	AB	CRediT	Conception and design of the project	Conception and design of the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
6043907	29880602	AM-L	CRediT	methodology	methodology	Performed the experiments	Methodology	YES
6043907	29880602	AO	CRediT	methodology	methodology	Performed the experiments	Methodology	YES
6043907	29880602	BP	CRediT	methodology	methodology	Performed the experiments	Methodology	YES
6043907	29880602	CV-D	CRediT	Conception and design of the project|methodology	Conception and design of the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
6043907	29880602	CV-D	CRediT	Conception and design of the project|methodology	methodology	Performed the experiments	Methodology	YES
6043907	29880602	DA-L	CRediT	methodology	methodology	Performed the experiments	Methodology	YES
6043907	29880602	FJGC	CRediT	methodology	methodology	Performed the experiments	Methodology	YES
6043907	29880602	GR-H	CRediT	methodology	methodology	Performed the experiments	Methodology	YES
6043907	29880602	IG-H	CRediT	methodology	methodology	Performed the experiments	Methodology	YES
6043907	29880602	IG-R	CRediT	Conception and design of the project|methodology	Conception and design of the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
6043907	29880602	IG-R	CRediT	Conception and design of the project|methodology	methodology	Performed the experiments	Methodology	YES
6043907	29880602	IS-G	CRediT	Conception and design of the project	Conception and design of the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
6043907	29880602	JDLR	CRediT	methodology	methodology	Performed the experiments	Methodology	YES
6043907	29880602	JH	CRediT	Conception and design of the project	Conception and design of the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
6043907	29880602	MBGC	CRediT	methodology	methodology	Performed the experiments	Methodology	YES
6043907	29880602	OB	CRediT	methodology	methodology	Performed the experiments	Methodology	YES
6043907	29880602	RJ	CRediT	methodology	methodology	Performed the experiments	Methodology	YES
6043907	29880602	SB	CRediT	methodology	methodology	Performed the experiments	Methodology	YES
6043907	29880602	SGT-D	CRediT	methodology	methodology	Performed the experiments	Methodology	YES
6043907	29880602	SP	CRediT	methodology	methodology	Performed the experiments	Methodology	YES
6043907	29880602	VD	CRediT	methodology	methodology	Performed the experiments	Methodology	YES
6043907	29880602	YN	CRediT	methodology	methodology	Performed the experiments	Methodology	YES
1964519	17849011	EC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1964519	17849011	JL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1964519	17849011	MC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1964519	17849011	MC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1964519	17849011	MF	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1964519	17849011	NA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1964519	17849011	NA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1964519	17849011	NA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1964519	17849011	NA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5747089	29284399	EF	PLoS52	performed the research|analyzed the data|designed the research and wrote the paper	performed the research	Performed the experiments	Investigation	YES
5747089	29284399	EF	PLoS52	performed the research|analyzed the data|designed the research and wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5747089	29284399	EF	PLoS52	performed the research|analyzed the data|designed the research and wrote the paper	designed the research and wrote the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5747089	29284399	EM	PLoS52	performed the research|analyzed the data	performed the research	Performed the experiments	Investigation	YES
5747089	29284399	EM	PLoS52	performed the research|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5747089	29284399	JMJG	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5747089	29284399	LL	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5747089	29284399	LST	PLoS52	performed deep sequencing and degs analysis	performed deep sequencing and degs analysis	Performed the experiments	Investigation	YES
4416797	25933104	HBZ	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416797	25933104	JYC	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416797	25933104	LH	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416797	25933104	SBC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416797	25933104	SSZ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416797	25933104	ZL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416797	25933104	ZL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416797	25933104	ZL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416797	25933104	ZL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5801424	29456548	PC	2	conceived and wrote the paper	conceived and wrote the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5801424	29456548	The author	2	confirms being the sole contributor of this work and approved it for publication	confirms being the sole contributor of this work and approved it for publication	-	-	NO
4359042	24844187	A Tanaka	PLoS52	carried out the literature search|carried out the statistical analysis	carried out the literature search	Performed the experiments	Formal analysis|Investigation	YES
4359042	24844187	A Tanaka	PLoS52	carried out the literature search|carried out the statistical analysis	carried out the statistical analysis	Analyzed the data	Formal analysis	YES
4359042	24844187	H Shiratsuchi	PLoS52	acquired the data	acquired the data	Performed the experiments	Investigation	YES
4359042	24844187	M Moriyama	PLoS52	defined the intellectual content|carried out the literature search|carried out the statistical analysis|prepared and edited the manuscript	defined the intellectual content	-	-	NO
4359042	24844187	M Moriyama	PLoS52	defined the intellectual content|carried out the literature search|carried out the statistical analysis|prepared and edited the manuscript	carried out the literature search	Performed the experiments	Formal analysis|Investigation	YES
4359042	24844187	M Moriyama	PLoS52	defined the intellectual content|carried out the literature search|carried out the statistical analysis|prepared and edited the manuscript	carried out the statistical analysis	Analyzed the data	Formal analysis	YES
4359042	24844187	M Moriyama	PLoS52	defined the intellectual content|carried out the literature search|carried out the statistical analysis|prepared and edited the manuscript	prepared and edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4359042	24844187	M Ohta	PLoS52	acquired the data	acquired the data	Performed the experiments	Investigation	YES
4359042	24844187	N Hayashida	PLoS52	carried out the experimental studies	carried out the experimental studies	Performed the experiments	Investigation	YES
4359042	24844187	S Furukawa	PLoS52	defined the intellectual content|carried out the literature search|analysed the data|carried out the statistical analysis	defined the intellectual content	-	-	NO
4359042	24844187	S Furukawa	PLoS52	defined the intellectual content|carried out the literature search|analysed the data|carried out the statistical analysis	carried out the literature search	Performed the experiments	Formal analysis|Investigation	YES
4359042	24844187	S Furukawa	PLoS52	defined the intellectual content|carried out the literature search|analysed the data|carried out the statistical analysis	analysed the data	Analyzed the data	Formal analysis	YES
4359042	24844187	S Furukawa	PLoS52	defined the intellectual content|carried out the literature search|analysed the data|carried out the statistical analysis	carried out the statistical analysis	Analyzed the data	Formal analysis	YES
4359042	24844187	S Kawano	PLoS52	acquired the data	acquired the data	Performed the experiments	Investigation	YES
4359042	24844187	T Kiyoshima	PLoS52	analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
4359042	24844187	Y Goto	PLoS52	carried out the experimental studies	carried out the experimental studies	Performed the experiments	Investigation	YES
4359042	24844187	Y Imabayashi	PLoS52	acquired the data	acquired the data	Performed the experiments	Investigation	YES
4359042	24844187	Y Ohyama	PLoS52	acquired the data	acquired the data	Performed the experiments	Investigation	YES
4874406	27216525	C.D.A.	2	carried out field collections, analyses of specimens and data, and assisted in writing the paper	carried out field collections, analyses of specimens and data, and assisted in writing the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4874406	27216525	C.I.R.	2	assisted in analyses of data and writing of the paper	assisted in analyses of data and writing of the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4874406	27216525	D.A.F.	2	carried out field collections, analyses of specimens and data, and assisted in writing the paper	carried out field collections, analyses of specimens and data, and assisted in writing the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4874406	27216525	J.F.	2	carried out field collections, analyses of specimens and data, and assisted in writing the paper	carried out field collections, analyses of specimens and data, and assisted in writing the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4874406	27216525	M.J.L.	2	assisted in analyses of data and writing of the paper	assisted in analyses of data and writing of the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4874406	27216525	T.W.S.	2	designed the study, carried out field collections, analyses of specimens and data, and led the writing of the paper	designed the study, carried out field collections, analyses of specimens and data, and led the writing of the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5622017	28963660	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5622017	28963660	PH	PLoS52	conceived and designed the experiments|performed the experiments|performed the data analysis	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5622017	28963660	PH	PLoS52	conceived and designed the experiments|performed the experiments|performed the data analysis	performed the experiments	Performed the experiments	Investigation	YES
5622017	28963660	PH	PLoS52	conceived and designed the experiments|performed the experiments|performed the data analysis	performed the data analysis	Analyzed the data	Formal analysis	YES
5622017	28963660	QL	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5622017	28963660	SL	PLoS52	conceived and designed the experiments|performed the data analysis|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5622017	28963660	SL	PLoS52	conceived and designed the experiments|performed the data analysis|wrote the paper	performed the data analysis	Analyzed the data	Formal analysis	YES
5622017	28963660	SL	PLoS52	conceived and designed the experiments|performed the data analysis|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5622017	28963660	The authors	PLoS52	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5622017	28963660	YX	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5622017	28963660	YY	PLoS52	conceived and designed the experiments|performed the data analysis	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5622017	28963660	YY	PLoS52	conceived and designed the experiments|performed the data analysis	performed the data analysis	Analyzed the data	Formal analysis	YES
5622017	28963660	YZ	PLoS52	conceived and designed the experiments|performed the experiments|performed the data analysis|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5622017	28963660	YZ	PLoS52	conceived and designed the experiments|performed the experiments|performed the data analysis|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5622017	28963660	YZ	PLoS52	conceived and designed the experiments|performed the experiments|performed the data analysis|wrote the paper	performed the data analysis	Analyzed the data	Formal analysis	YES
5622017	28963660	YZ	PLoS52	conceived and designed the experiments|performed the experiments|performed the data analysis|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5622017	28963660	Zuoxiong Liu	PLoS52	for critical reading of the manuscript	for critical reading of the manuscript	-	-	NO
6043908	29934293	EF	CRediT	methodology	methodology	Performed the experiments	Methodology	YES
6043908	29934293	EM	CRediT	investigation	investigation	Performed the experiments	Investigation	YES
6043908	29934293	GAM	CRediT	Conceptualization|methodology|investigation	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6043908	29934293	GAM	CRediT	Conceptualization|methodology|investigation	methodology	Performed the experiments	Methodology	YES
6043908	29934293	GAM	CRediT	Conceptualization|methodology|investigation	investigation	Performed the experiments	Investigation	YES
6043908	29934293	IW	CRediT	methodology|funding acquisition	methodology	Performed the experiments	Methodology	YES
6043908	29934293	IW	CRediT	methodology|funding acquisition	funding acquisition	-	Funding acquisition	YES
6043908	29934293	JK	CRediT	methodology|investigation	methodology	Performed the experiments	Methodology	YES
6043908	29934293	JK	CRediT	methodology|investigation	investigation	Performed the experiments	Investigation	YES
6043908	29934293	JNL	CRediT	methodology|investigation	methodology	Performed the experiments	Methodology	YES
6043908	29934293	JNL	CRediT	methodology|investigation	investigation	Performed the experiments	Investigation	YES
6043908	29934293	MJS	CRediT	methodology|investigation	methodology	Performed the experiments	Methodology	YES
6043908	29934293	MJS	CRediT	methodology|investigation	investigation	Performed the experiments	Investigation	YES
6043908	29934293	MW	CRediT	methodology|investigation	methodology	Performed the experiments	Methodology	YES
6043908	29934293	MW	CRediT	methodology|investigation	investigation	Performed the experiments	Investigation	YES
6043908	29934293	PT	CRediT	Conceptualization|methodology|investigation	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6043908	29934293	PT	CRediT	Conceptualization|methodology|investigation	methodology	Performed the experiments	Methodology	YES
6043908	29934293	PT	CRediT	Conceptualization|methodology|investigation	investigation	Performed the experiments	Investigation	YES
6043908	29934293	REL	CRediT	Conceptualization|methodology|funding acquisition	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6043908	29934293	REL	CRediT	Conceptualization|methodology|funding acquisition	methodology	Performed the experiments	Methodology	YES
6043908	29934293	REL	CRediT	Conceptualization|methodology|funding acquisition	funding acquisition	-	Funding acquisition	YES
6043908	29934293	RSW	CRediT	Conceptualization|methodology|investigation|writing--original draft|funding acquisition	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6043908	29934293	RSW	CRediT	Conceptualization|methodology|investigation|writing--original draft|funding acquisition	methodology	Performed the experiments	Methodology	YES
6043908	29934293	RSW	CRediT	Conceptualization|methodology|investigation|writing--original draft|funding acquisition	investigation	Performed the experiments	Investigation	YES
6043908	29934293	RSW	CRediT	Conceptualization|methodology|investigation|writing--original draft|funding acquisition	writing--original draft	Wrote the paper	Writing - Original Draft	YES
6043908	29934293	RSW	CRediT	Conceptualization|methodology|investigation|writing--original draft|funding acquisition	funding acquisition	-	Funding acquisition	YES
5747110	29284403	DB	2	carried out the material preparation for the sequencing procedure and bioinformatics analyses	carried out the material preparation for the sequencing procedure and bioinformatics analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5747110	29284403	HK	2	came up with research ideas|supervised the performed analyses|wrote the final version of the manuscript	came up with research ideas	Conceived and designed the experiments	Conceptualization	YES
5747110	29284403	HK	2	came up with research ideas|supervised the performed analyses|wrote the final version of the manuscript	supervised the performed analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Supervision	YES
5747110	29284403	HK	2	came up with research ideas|supervised the performed analyses|wrote the final version of the manuscript	wrote the final version of the manuscript	Wrote the paper	Writing - Original Draft	YES
5747110	29284403	MW	2	came up with research ideas|wrote the final version of the manuscript|provided the a	came up with research ideas	Conceived and designed the experiments	Conceptualization	YES
5747110	29284403	MW	2	came up with research ideas|wrote the final version of the manuscript|provided the a	wrote the final version of the manuscript	Wrote the paper	Writing - Original Draft	YES
5747110	29284403	MW	2	came up with research ideas|wrote the final version of the manuscript|provided the a	provided the a	-	-	NO
5747110	29284403	WM	2	came up with research ideas|supervised the performed analyses|wrote the final version of the manuscript	came up with research ideas	Conceived and designed the experiments	Conceptualization	YES
5747110	29284403	WM	2	came up with research ideas|supervised the performed analyses|wrote the final version of the manuscript	supervised the performed analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Supervision	YES
5747110	29284403	WM	2	came up with research ideas|supervised the performed analyses|wrote the final version of the manuscript	wrote the final version of the manuscript	Wrote the paper	Writing - Original Draft	YES
5747110	29284403	YS	2	conceived the transcriptome sequencing	conceived the transcriptome sequencing	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5801560	29456545	All authors	PLoS52	commented on an earlier draft of manuscript	commented on an earlier draft of manuscript	Wrote the paper	Writing - Original Draft	YES
5801560	29456545	DC	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5801560	29456545	HB	PLoS52	developed the idea|assisted with the wrote the paper with	developed the idea	Conceived and designed the experiments	Conceptualization	YES
5801560	29456545	HB	PLoS52	developed the idea|assisted with the wrote the paper with	assisted with the wrote the paper with	Wrote the paper	Writing - Original Draft	YES
5801560	29456545	KS-J	PLoS52	developed the idea|extracted the remaining data|analyzed the data|wrote the paper with	developed the idea	Conceived and designed the experiments	Conceptualization	YES
5801560	29456545	KS-J	PLoS52	developed the idea|extracted the remaining data|analyzed the data|wrote the paper with	extracted the remaining data	Performed the experiments	Investigation	YES
5801560	29456545	KS-J	PLoS52	developed the idea|extracted the remaining data|analyzed the data|wrote the paper with	analyzed the data	Analyzed the data	Formal analysis	YES
5801560	29456545	KS-J	PLoS52	developed the idea|extracted the remaining data|analyzed the data|wrote the paper with	wrote the paper with	Wrote the paper	Writing - Original Draft	YES
5801560	29456545	LB-S	PLoS52	developed the idea|extracted the remaining data|analyzed the data|performed the statistical analysis|assisted with the wrote the paper with	developed the idea	Conceived and designed the experiments	Conceptualization	YES
5801560	29456545	LB-S	PLoS52	developed the idea|extracted the remaining data|analyzed the data|performed the statistical analysis|assisted with the wrote the paper with	extracted the remaining data	Performed the experiments	Investigation	YES
5801560	29456545	LB-S	PLoS52	developed the idea|extracted the remaining data|analyzed the data|performed the statistical analysis|assisted with the wrote the paper with	analyzed the data	Analyzed the data	Formal analysis	YES
5801560	29456545	LB-S	PLoS52	developed the idea|extracted the remaining data|analyzed the data|performed the statistical analysis|assisted with the wrote the paper with	performed the statistical analysis	Analyzed the data	Formal analysis	YES
5801560	29456545	LB-S	PLoS52	developed the idea|extracted the remaining data|analyzed the data|performed the statistical analysis|assisted with the wrote the paper with	assisted with the wrote the paper with	Wrote the paper	Writing - Original Draft	YES
5801560	29456545	PH	PLoS52	extracted the remaining data	extracted the remaining data	Performed the experiments	Investigation	YES
5801560	29456545	TN	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
1964532	17849004	JA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1964532	17849004	JA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1964532	17849004	JA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1964532	17849004	JA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1964532	17849004	NH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1964532	17849004	NH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1964532	17849004	NH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1964532	17849004	NH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1964532	17849004	TH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1964532	17849004	TH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1964532	17849004	TH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1964532	17849004	TH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416798	25932947	GL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Drafted the article|Final approval|Agreed to be accountable for all aspects of the work	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416798	25932947	GL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Drafted the article|Final approval|Agreed to be accountable for all aspects of the work	Performed the experiments	Performed the experiments	Investigation	YES
4416798	25932947	GL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Drafted the article|Final approval|Agreed to be accountable for all aspects of the work	Analyzed the data	Analyzed the data	Formal analysis	YES
4416798	25932947	GL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Drafted the article|Final approval|Agreed to be accountable for all aspects of the work	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416798	25932947	GL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Drafted the article|Final approval|Agreed to be accountable for all aspects of the work	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416798	25932947	GL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Drafted the article|Final approval|Agreed to be accountable for all aspects of the work	Drafted the article	Wrote the paper	Writing - Original Draft	YES
4416798	25932947	GL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Drafted the article|Final approval|Agreed to be accountable for all aspects of the work	Final approval	-	-	NO
4416798	25932947	GL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Drafted the article|Final approval|Agreed to be accountable for all aspects of the work	Agreed to be accountable for all aspects of the work	-	-	NO
4416798	25932947	JM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Revised the article|Final approval|Agreed to be accountable for all aspects of the work	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416798	25932947	JM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Revised the article|Final approval|Agreed to be accountable for all aspects of the work	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416798	25932947	JM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Revised the article|Final approval|Agreed to be accountable for all aspects of the work	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416798	25932947	JM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Revised the article|Final approval|Agreed to be accountable for all aspects of the work	Revised the article	Wrote the paper	Writing - Review & Editing	YES
4416798	25932947	JM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Revised the article|Final approval|Agreed to be accountable for all aspects of the work	Final approval	-	-	NO
4416798	25932947	JM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Revised the article|Final approval|Agreed to be accountable for all aspects of the work	Agreed to be accountable for all aspects of the work	-	-	NO
4440386	25431241	E. B. Tuna	2	involved in sample collection and screened the patients	involved in sample collection and screened the patients	Performed the experiments	Investigation	YES
4440386	25431241	F. Seymen	2	involved in sample collection and screened the patients	involved in sample collection and screened the patients	Performed the experiments	Investigation	YES
4440386	25431241	K. Gencay	2	involved in sample collection and screened the patients	involved in sample collection and screened the patients	Performed the experiments	Investigation	YES
4440386	25431241	M. Bayram	2	involved in sample collection and screened the patients	involved in sample collection and screened the patients	Performed the experiments	Investigation	YES
4440386	25431241	M. Koruyucu	2	involved in sample collection and screened the patients	involved in sample collection and screened the patients	Performed the experiments	Investigation	YES
4440386	25431241	W. Kim	2	performed experiment and analyzed the data|designed the study and drafted the manuscript	performed experiment and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4440386	25431241	W. Kim	2	performed experiment and analyzed the data|designed the study and drafted the manuscript	designed the study and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
6270703	24739929	All authors	PLoS52	discussed and approved the final manuscript	discussed and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6270703	24739929	Chi-Chang Huang	PLoS52	designed the experiments|carried out the laboratory experiments|analyzed the data, interpreted the results, prepared figures, and wrote the manuscript|contributed reagents, materials, analysis tools|edited and revised the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
6270703	24739929	Chi-Chang Huang	PLoS52	designed the experiments|carried out the laboratory experiments|analyzed the data, interpreted the results, prepared figures, and wrote the manuscript|contributed reagents, materials, analysis tools|edited and revised the manuscript	carried out the laboratory experiments	Performed the experiments	Investigation	YES
6270703	24739929	Chi-Chang Huang	PLoS52	designed the experiments|carried out the laboratory experiments|analyzed the data, interpreted the results, prepared figures, and wrote the manuscript|contributed reagents, materials, analysis tools|edited and revised the manuscript	analyzed the data, interpreted the results, prepared figures, and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Visualization|Writing - Original Draft	YES
6270703	24739929	Chi-Chang Huang	PLoS52	designed the experiments|carried out the laboratory experiments|analyzed the data, interpreted the results, prepared figures, and wrote the manuscript|contributed reagents, materials, analysis tools|edited and revised the manuscript	contributed reagents, materials, analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
6270703	24739929	Chi-Chang Huang	PLoS52	designed the experiments|carried out the laboratory experiments|analyzed the data, interpreted the results, prepared figures, and wrote the manuscript|contributed reagents, materials, analysis tools|edited and revised the manuscript	edited and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
6270703	24739929	Chin-Shan Ho	PLoS52	measured forelimb grip strength	measured forelimb grip strength	Performed the experiments	Investigation	YES
6270703	24739929	Hui-Ling Chao	PLoS52	carried out the laboratory experiments	carried out the laboratory experiments	Performed the experiments	Investigation	YES
6270703	24739929	Mei-Chich Hsu	PLoS52	designed the experiments|contributed reagents, materials, analysis tools|edited and revised the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
6270703	24739929	Mei-Chich Hsu	PLoS52	designed the experiments|contributed reagents, materials, analysis tools|edited and revised the manuscript	contributed reagents, materials, analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
6270703	24739929	Mei-Chich Hsu	PLoS52	designed the experiments|contributed reagents, materials, analysis tools|edited and revised the manuscript	edited and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
6270703	24739929	Nai-Wen Kan	PLoS52	edited and revised the manuscript	edited and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
6270703	24739929	Yi-Ming Chen	PLoS52	analyzed the data, interpreted the results, prepared figures, and wrote the manuscript	analyzed the data, interpreted the results, prepared figures, and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Visualization|Writing - Original Draft	YES
5622018	28963704	AMA	2	planning and practically conduct of research work	planning and practically conduct of research work	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5622018	28963704	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5622018	28963704	BA	2	collection of samples and data analysis	collection of samples and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5622018	28963704	Faisalabad Pakistan	2	for their help and support in molecular characterization of bacterial strain	for their help and support in molecular characterization of bacterial strain	Performed the experiments	Investigation	YES
5622018	28963704	MHR	2	supervised the research work, manuscript write up and submission	supervised the research work, manuscript write up and submission	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Original Draft	YES
5622018	28963704	MW	2	compilation and analysis of data	compilation and analysis of data	Analyzed the data	Formal analysis	YES
5622018	28963704	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
4874407	27216526	All authors	2	gave final approval for publication	gave final approval for publication	-	-	NO
4874407	27216526	B.P.M.	2	drew the figures	drew the figures	-	Visualization	YES
4874407	27216526	D.M.J.S.B.	2	conceived and drafted the manuscript	conceived and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4874407	27216526	G.L.W.P.	2	drew the figures	drew the figures	-	Visualization	YES
4874407	27216526	all authors	2	critically reviewed early versions of the manuscript and provided guidance for improvement	critically reviewed early versions of the manuscript and provided guidance for improvement	Wrote the paper	Supervision|Writing - Review & Editing	YES
4416799	25932634	AA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416799	25932634	AA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416799	25932634	AA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416799	25932634	AA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416799	25932634	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416799	25932634	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416799	25932634	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416799	25932634	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416799	25932634	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416799	25932634	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416799	25932634	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416799	25932634	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416799	25932634	KG	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416799	25932634	KG	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416799	25932634	MH	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416799	25932634	MH	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416799	25932634	MS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
6068430	29789391	DEP	2	conceived the project and designed the research|performed and analysed experiments|wrote the manuscript	conceived the project and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
6068430	29789391	DEP	2	conceived the project and designed the research|performed and analysed experiments|wrote the manuscript	performed and analysed experiments	Performed the experiments	Investigation	YES
6068430	29789391	DEP	2	conceived the project and designed the research|performed and analysed experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6068430	29789391	DPE	2	performed and analysed experiments	performed and analysed experiments	Performed the experiments	Investigation	YES
6068430	29789391	EON	2	conceived the project and designed the research|wrote the manuscript	conceived the project and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
6068430	29789391	EON	2	conceived the project and designed the research|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6068430	29789391	MLT	2	performed and analysed experiments	performed and analysed experiments	Performed the experiments	Investigation	YES
6068430	29789391	VG	2	offered reagents and scientific advice	offered reagents and scientific advice	-	-	NO
5801561	29456549	D-HK	2	supervised the experiments|prepared the figures and edited the manuscript|wrote the manuscript	supervised the experiments	-	Supervision	YES
5801561	29456549	D-HK	2	supervised the experiments|prepared the figures and edited the manuscript|wrote the manuscript	prepared the figures and edited the manuscript	Wrote the paper	Visualization|Writing - Original Draft|Writing - Review & Editing	YES
5801561	29456549	D-HK	2	supervised the experiments|prepared the figures and edited the manuscript|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5801561	29456549	J-MK	2	designed the experiments|prepared the figures and edited the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5801561	29456549	J-MK	2	designed the experiments|prepared the figures and edited the manuscript	prepared the figures and edited the manuscript	Wrote the paper	Visualization|Writing - Original Draft|Writing - Review & Editing	YES
5801561	29456549	JB	2	performed gene replacement experiments and functional analysis of mutants	performed gene replacement experiments and functional analysis of mutants	Performed the experiments	Investigation	YES
5801561	29456549	JHH	2	designed wgbs and analyzed the data	designed wgbs and analyzed the data	Conceived and designed the experiments|Analyzed the data	Formal analysis	YES
5801561	29456549	JJ	2	designed wgbs and analyzed the data	designed wgbs and analyzed the data	Conceived and designed the experiments|Analyzed the data	Formal analysis	YES
5801561	29456549	JaC	2	designed wgbs and analyzed the data	designed wgbs and analyzed the data	Conceived and designed the experiments|Analyzed the data	Formal analysis	YES
5801561	29456549	JeC	2	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5801561	29456549	K-KS	2	performed gene replacement experiments and functional analysis of mutants|prepared the figures and edited the manuscript	performed gene replacement experiments and functional analysis of mutants	Performed the experiments	Investigation	YES
5801561	29456549	K-KS	2	performed gene replacement experiments and functional analysis of mutants|prepared the figures and edited the manuscript	prepared the figures and edited the manuscript	Wrote the paper	Visualization|Writing - Original Draft|Writing - Review & Editing	YES
5801561	29456549	Y-HK	2	performed gene replacement experiments and functional analysis of mutants	performed gene replacement experiments and functional analysis of mutants	Performed the experiments	Investigation	YES
5801561	29456549	Y-HL	2	designed wgbs and analyzed the data	designed wgbs and analyzed the data	Conceived and designed the experiments|Analyzed the data	Formal analysis	YES
1964533	17849005	AG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1964533	17849005	AG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1964533	17849005	AG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1964533	17849005	AG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1964533	17849005	JN	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1964533	17849005	JV	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1964533	17849005	JV	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1964533	17849005	MD	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1964533	17849005	MD	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1964533	17849005	RB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1964533	17849005	RB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1964533	17849005	RB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1964533	17849005	RB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1964533	17849005	RC	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1964533	17849005	RR	PLoS5	Pathological analysis	Pathological analysis	Performed the experiments	Investigation	YES
5747113	29284410	EI	PLoS52	designed the study and wrote the manuscript|performed the bioinformatic analysis and analyzed the data|performed the experiments	designed the study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5747113	29284410	EI	PLoS52	designed the study and wrote the manuscript|performed the bioinformatic analysis and analyzed the data|performed the experiments	performed the bioinformatic analysis and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5747113	29284410	EI	PLoS52	designed the study and wrote the manuscript|performed the bioinformatic analysis and analyzed the data|performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5747113	29284410	KW	PLoS52	performed the bioinformatic analysis and analyzed the data	performed the bioinformatic analysis and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5747113	29284410	SI	PLoS52	designed the study and wrote the manuscript|performed the bioinformatic analysis and analyzed the data|performed the experiments	designed the study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5747113	29284410	SI	PLoS52	designed the study and wrote the manuscript|performed the bioinformatic analysis and analyzed the data|performed the experiments	performed the bioinformatic analysis and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5747113	29284410	SI	PLoS52	designed the study and wrote the manuscript|performed the bioinformatic analysis and analyzed the data|performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5747113	29284410	YN	PLoS52	designed the study and wrote the manuscript|performed the bioinformatic analysis and analyzed the data	designed the study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5747113	29284410	YN	PLoS52	designed the study and wrote the manuscript|performed the bioinformatic analysis and analyzed the data	performed the bioinformatic analysis and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5622019	28963644	AJR	2	is the corresponding author and principal investigator	is the corresponding author and principal investigator	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
5622019	28963644	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6270704	25532841	Denis Kozlov	2	analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6270704	25532841	Dmitry Selishchev	2	synthesized the photocatalysts and performed experiments|analyzed the data and wrote the manuscript	synthesized the photocatalysts and performed experiments	Performed the experiments	Investigation	YES
6270704	25532841	Dmitry Selishchev	2	synthesized the photocatalysts and performed experiments|analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4874416	27216511	J.A.	2	provided the introductory framework and editing	provided the introductory framework and editing	Wrote the paper	Writing - Review & Editing	YES
4874416	27216511	J.M.	2	wrote on national challenges, policy and statistical evidence	wrote on national challenges, policy and statistical evidence	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4874416	27216511	R.G.	2	is the lead author and instrumental in setting the content of the paper	is the lead author and instrumental in setting the content of the paper	-	-	NO
1964534	17849010	KR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1964534	17849010	KR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1964534	17849010	KR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1964534	17849010	KR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1964534	17849010	KV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1964534	17849010	KV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1964534	17849010	KV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1964534	17849010	KV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1964534	17849010	NC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1964534	17849010	NC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1964534	17849010	NC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1964534	17849010	SV	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1964534	17849010	SV	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1964534	17849010	SV	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416800	25933052	AFM	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4416800	25933052	AFM	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416800	25933052	AXC	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4416800	25933052	AXC	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416800	25933052	AXM	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416800	25933052	CS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416800	25933052	CS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416800	25933052	HM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416800	25933052	HM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416800	25933052	HM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416800	25933052	PP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416800	25933052	SAR	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416800	25933052	WB	PLoS5	Advice with elutriation	Advice with elutriation	-	-	NO
4416800	25933052	WCE	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5801577	29456543	All authors	2	contributed to the planning and designing of the experiments and to the drafting of the manuscript	contributed to the planning and designing of the experiments and to the drafting of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5801577	29456543	MM	2	performed the bioassays and elisa analyses|analyzed the data statistically	performed the bioassays and elisa analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5801577	29456543	MM	2	performed the bioassays and elisa analyses|analyzed the data statistically	analyzed the data statistically	Analyzed the data	Formal analysis	YES
5801577	29456543	YS	2	performed the bioassays and elisa analyses	performed the bioassays and elisa analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6068448	29959219	APJ	2	directed and designed the study	directed and designed the study	Conceived and designed the experiments	Methodology|Supervision	YES
6068448	29959219	AS-P	2	provided valuable input throughout the project	provided valuable input throughout the project	-	-	NO
6068448	29959219	JLG-P	2	directed and designed the study|wrote the manuscript, with input from all authors	directed and designed the study	Conceived and designed the experiments	Methodology|Supervision	YES
6068448	29959219	JLG-P	2	directed and designed the study|wrote the manuscript, with input from all authors	wrote the manuscript, with input from all authors	Wrote the paper	Writing - Original Draft	YES
6068448	29959219	MAMR	2	directed and designed the study|wrote the manuscript, with input from all authors	directed and designed the study	Conceived and designed the experiments	Methodology|Supervision	YES
6068448	29959219	MAMR	2	directed and designed the study|wrote the manuscript, with input from all authors	wrote the manuscript, with input from all authors	Wrote the paper	Writing - Original Draft	YES
6068448	29959219	SRH	2	provided valuable input throughout the project	provided valuable input throughout the project	-	-	NO
6068448	29959219	TCW	2	conducted the tandem repeat sequence analyses	conducted the tandem repeat sequence analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270705	24451254	A.P.	2	conceived the study|prepared samples and performed ssnmr and other characterizations	conceived the study	Conceived and designed the experiments	Conceptualization	YES
6270705	24451254	A.P.	2	conceived the study|prepared samples and performed ssnmr and other characterizations	prepared samples and performed ssnmr and other characterizations	Performed the experiments	Investigation	YES
6270705	24451254	L.Z.	2	prepared samples and performed ssnmr and other characterizations|analyzed the nmr data and made the figures	prepared samples and performed ssnmr and other characterizations	Performed the experiments	Investigation	YES
6270705	24451254	L.Z.	2	prepared samples and performed ssnmr and other characterizations|analyzed the nmr data and made the figures	analyzed the nmr data and made the figures	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
6270705	24451254	R.C.	2	prepared samples and performed ssnmr and other characterizations	prepared samples and performed ssnmr and other characterizations	Performed the experiments	Investigation	YES
6270705	24451254	S.L.	2	conceived the study|prepared samples and performed ssnmr and other characterizations|analyzed the nmr data and made the figures|wrote the paper and all authors contributed to the editing of the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
6270705	24451254	S.L.	2	conceived the study|prepared samples and performed ssnmr and other characterizations|analyzed the nmr data and made the figures|wrote the paper and all authors contributed to the editing of the manuscript	prepared samples and performed ssnmr and other characterizations	Performed the experiments	Investigation	YES
6270705	24451254	S.L.	2	conceived the study|prepared samples and performed ssnmr and other characterizations|analyzed the nmr data and made the figures|wrote the paper and all authors contributed to the editing of the manuscript	analyzed the nmr data and made the figures	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
6270705	24451254	S.L.	2	conceived the study|prepared samples and performed ssnmr and other characterizations|analyzed the nmr data and made the figures|wrote the paper and all authors contributed to the editing of the manuscript	wrote the paper and all authors contributed to the editing of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6270705	24451254	W.H.	2	conceived the study|prepared samples and performed ssnmr and other characterizations|wrote the paper and all authors contributed to the editing of the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
6270705	24451254	W.H.	2	conceived the study|prepared samples and performed ssnmr and other characterizations|wrote the paper and all authors contributed to the editing of the manuscript	prepared samples and performed ssnmr and other characterizations	Performed the experiments	Investigation	YES
6270705	24451254	W.H.	2	conceived the study|prepared samples and performed ssnmr and other characterizations|wrote the paper and all authors contributed to the editing of the manuscript	wrote the paper and all authors contributed to the editing of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6270705	24451254	X.M.	2	prepared samples and performed ssnmr and other characterizations	prepared samples and performed ssnmr and other characterizations	Performed the experiments	Investigation	YES
6270705	24451254	Y.S.	2	conceived the study|analyzed the nmr data and made the figures|wrote the paper and all authors contributed to the editing of the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
6270705	24451254	Y.S.	2	conceived the study|analyzed the nmr data and made the figures|wrote the paper and all authors contributed to the editing of the manuscript	analyzed the nmr data and made the figures	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
6270705	24451254	Y.S.	2	conceived the study|analyzed the nmr data and made the figures|wrote the paper and all authors contributed to the editing of the manuscript	wrote the paper and all authors contributed to the editing of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
1964535	17849019	AP	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1964535	17849019	AP	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1964535	17849019	KS	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1964535	17849019	KS	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1964535	17849019	SL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1964535	17849019	SL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1964535	17849019	SL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1964535	17849019	SL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5622026	28963711	AL	2	role in experimental work, data interpretation and discussion and manuscript writing	role in experimental work, data interpretation and discussion and manuscript writing	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5622026	28963711	AW	2	role in supervision, data interpretation and discussion, and manuscript writing	role in supervision, data interpretation and discussion, and manuscript writing	Analyzed the data|Wrote the paper	Formal analysis|Supervision|Writing - Original Draft	YES
5622026	28963711	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5622026	28963711	Food Science	2	for fruitful scientific discussions on enzyme-substrate specificity and experimental design	for fruitful scientific discussions on enzyme-substrate specificity and experimental design	Conceived and designed the experiments	Methodology	YES
5622026	28963711	JZ	2	role in experimental work, data interpretation and discussion and manuscript writing	role in experimental work, data interpretation and discussion and manuscript writing	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5622026	28963711	MEZ	2	primarily a role in experimental work, data interpretation and discussion	primarily a role in experimental work, data interpretation and discussion	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5622026	28963711	MRL	2	role in supervision, data interpretation and discussion, and manuscript writing	role in supervision, data interpretation and discussion, and manuscript writing	Analyzed the data|Wrote the paper	Formal analysis|Supervision|Writing - Original Draft	YES
5622026	28963711	OA	2	primarily a role in experimental work, data interpretation and discussion	primarily a role in experimental work, data interpretation and discussion	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5622026	28963711	TH	2	primarily a role in experimental work, data interpretation and discussion	primarily a role in experimental work, data interpretation and discussion	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5622026	28963711	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5622026	28963711	VTTP	2	primarily a role in experimental work, data interpretation and discussion	primarily a role in experimental work, data interpretation and discussion	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5622026	28963711	WL	2	primarily a role in supervision and data discussion	primarily a role in supervision and data discussion	-	Supervision	YES
4416801	25933220	BFJ	PLoS5	Contributed reagents/materials/analysis tools|Revised the final draft	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416801	25933220	BFJ	PLoS5	Contributed reagents/materials/analysis tools|Revised the final draft	Revised the final draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4416801	25933220	CL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4416801	25933220	CL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416801	25933220	HFH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Revised the final draft	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416801	25933220	HFH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Revised the final draft	Performed the experiments	Performed the experiments	Investigation	YES
4416801	25933220	HFH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Revised the final draft	Analyzed the data	Analyzed the data	Formal analysis	YES
4416801	25933220	HFH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Revised the final draft	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416801	25933220	HFH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Revised the final draft	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416801	25933220	HFH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Revised the final draft	Revised the final draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4416801	25933220	JBL	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416801	25933220	NY	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416801	25933220	NY	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416801	25933220	QG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416801	25933220	QWL	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416801	25933220	QWL	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416801	25933220	TS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1964536	17848990	CL	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1964536	17848990	CL	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1964536	17848990	CM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1964536	17848990	CS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1964536	17848990	GC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1964536	17848990	IM	PLoS5	Performed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1964536	17848990	IM	PLoS5	Performed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1964536	17848990	LM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1964536	17848990	MB	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1964536	17848990	MH	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1964536	17848990	MS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4874417	27216512	The authors	2	contributed equally to this publication	contributed equally to this publication	-	-	NO
5747154	29287583	All authors	PLoS52	contributed experimental design oversight	contributed experimental design oversight	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Supervision	YES
5747154	29287583	Berry Genomics	PLoS52	provided the plant tissue rna seq data	provided the plant tissue rna seq data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5747154	29287583	FL	PLoS52	performed the experiments|analyzed the data|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5747154	29287583	FL	PLoS52	performed the experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5747154	29287583	FL	PLoS52	performed the experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5747154	29287583	LW	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5747154	29287583	XY	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5747154	29287583	ZY	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
6270706	25264828	All authors	2	revised the draft and approved the version submitted	revised the draft and approved the version submitted	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6270706	25264828	D. Andrivon	2	drafted the paper	drafted the paper	Wrote the paper	Writing - Original Draft	YES
6270706	25264828	F. Gaillard	2	drafted the paper	drafted the paper	Wrote the paper	Writing - Original Draft	YES
6270706	25264828	F. Val	2	drafted the paper	drafted the paper	Wrote the paper	Writing - Original Draft	YES
6270706	25264828	G. Saubeau	2	drafted the paper	drafted the paper	Wrote the paper	Writing - Original Draft	YES
6270706	25264828	MS	2	analyses and analyzed data	analyses and analyzed data	Analyzed the data	Formal analysis	YES
6270706	25264828	V. Ferrieres	2	drafted the paper	drafted the paper	Wrote the paper	Writing - Original Draft	YES
4416802	25933188	ABC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416802	25933188	AS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416802	25933188	AS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416802	25933188	JC	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416802	25933188	JD	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416802	25933188	KR	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416802	25933188	LW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416802	25933188	MO	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416802	25933188	PT	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416802	25933188	PT	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416802	25933188	SFM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416802	25933188	SFM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416802	25933188	SFM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416802	25933188	SFM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5801592	29456547	All authors	2	were involved in the revision of the manuscript and approved the final manuscript	were involved in the revision of the manuscript and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5801592	29456547	CM	2	contributed to the study design	contributed to the study design	Conceived and designed the experiments	Methodology	YES
5801592	29456547	SC	2	carried out the public genome data collection	carried out the public genome data collection	Performed the experiments	Investigation	YES
5801592	29456547	SX	2	contributed to the study design|wrote the manuscript	contributed to the study design	Conceived and designed the experiments	Methodology	YES
5801592	29456547	SX	2	contributed to the study design|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5801592	29456547	XS	2	carried out the public genome data collection|performed the data analyses|wrote the manuscript	carried out the public genome data collection	Performed the experiments	Investigation	YES
5801592	29456547	XS	2	carried out the public genome data collection|performed the data analyses|wrote the manuscript	performed the data analyses	Analyzed the data	Formal analysis	YES
5801592	29456547	XS	2	carried out the public genome data collection|performed the data analyses|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5801592	29456547	XW	2	carried out the public genome data collection|performed the data analyses|contributed to the study design|wrote the manuscript	carried out the public genome data collection	Performed the experiments	Investigation	YES
5801592	29456547	XW	2	carried out the public genome data collection|performed the data analyses|contributed to the study design|wrote the manuscript	performed the data analyses	Analyzed the data	Formal analysis	YES
5801592	29456547	XW	2	carried out the public genome data collection|performed the data analyses|contributed to the study design|wrote the manuscript	contributed to the study design	Conceived and designed the experiments	Methodology	YES
5801592	29456547	XW	2	carried out the public genome data collection|performed the data analyses|contributed to the study design|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
1964537	17849015	CS	PLoS5	Performed the experiments|Editorial contributions	Performed the experiments	Performed the experiments	Investigation	YES
1964537	17849015	CS	PLoS5	Performed the experiments|Editorial contributions	Editorial contributions	-	-	NO
1964537	17849015	DB	PLoS5	Performed the experiments|Editorial contributions	Performed the experiments	Performed the experiments	Investigation	YES
1964537	17849015	DB	PLoS5	Performed the experiments|Editorial contributions	Editorial contributions	-	-	NO
1964537	17849015	GO	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1964537	17849015	JA	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1964537	17849015	JA	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1964537	17849015	KH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1964537	17849015	KH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1964537	17849015	KH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1964537	17849015	KH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1964537	17849015	KH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1964537	17849015	TH	PLoS5	Performed the experiments|Editorial contributions	Performed the experiments	Performed the experiments	Investigation	YES
1964537	17849015	TH	PLoS5	Performed the experiments|Editorial contributions	Editorial contributions	-	-	NO
1964537	17849015	TM	PLoS5	Contributed reagents/materials/analysis tools|Editorial contributions	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1964537	17849015	TM	PLoS5	Contributed reagents/materials/analysis tools|Editorial contributions	Editorial contributions	-	-	NO
4637014	26583097	Each author	2	has read and approved the content of the submitted paper	has read and approved the content of the submitted paper	-	-	NO
6068464	29950309	AD	PLoS52	conceived the project	conceived the project	Conceived and designed the experiments	Conceptualization	YES
6068464	29950309	AVo	PLoS52	performed the nanosims experiments	performed the nanosims experiments	Performed the experiments	Investigation	YES
6068464	29950309	EFF	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
6068464	29950309	HW	PLoS52	developed the mathematical model of the synaptic vesicle life cycle	developed the mathematical model of the synaptic vesicle life cycle	Performed the experiments	Formal analysis|Methodology	YES
6068464	29950309	SJ	PLoS52	performed the nanosims experiments	performed the nanosims experiments	Performed the experiments	Investigation	YES
6068464	29950309	SOR	PLoS52	conceived the project|analyzed the data|prepared the manuscript	conceived the project	Conceived and designed the experiments	Conceptualization	YES
6068464	29950309	SOR	PLoS52	conceived the project|analyzed the data|prepared the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
6068464	29950309	SOR	PLoS52	conceived the project|analyzed the data|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
6068464	29950309	ST	PLoS52	conceived the project|performed all other experiments|analyzed the data|prepared the manuscript	conceived the project	Conceived and designed the experiments	Conceptualization	YES
6068464	29950309	ST	PLoS52	conceived the project|performed all other experiments|analyzed the data|prepared the manuscript	performed all other experiments	Performed the experiments	Investigation	YES
6068464	29950309	ST	PLoS52	conceived the project|performed all other experiments|analyzed the data|prepared the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
6068464	29950309	ST	PLoS52	conceived the project|performed all other experiments|analyzed the data|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
6068464	29950309	STED	PLoS52	experiments on changes in synaptic vesicle protein levels	experiments on changes in synaptic vesicle protein levels	Performed the experiments	Investigation	YES
4901447	27269596	M.S.B.	2	conceived of and designed the experiments, and wrote the manuscript	conceived of and designed the experiments, and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
4901447	27269596	P.G.	2	conceived of and designed the experiments, and wrote the manuscript|conducted the experiments and analysed the data	conceived of and designed the experiments, and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
4901447	27269596	P.G.	2	conceived of and designed the experiments, and wrote the manuscript|conducted the experiments and analysed the data	conducted the experiments and analysed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5628084	28980170	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5628084	28980170	DKO	PLoS52	designed the experiments, interpreted the results, and wrote the manuscript	designed the experiments, interpreted the results, and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5628084	28980170	HYC	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5628084	28980170	KCS	PLoS52	designed the experiments, interpreted the results, and wrote the manuscript|performed the experiments	designed the experiments, interpreted the results, and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5628084	28980170	KCS	PLoS52	designed the experiments, interpreted the results, and wrote the manuscript|performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5628084	28980170	MJS	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5628084	28980170	The authors	PLoS52	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5747157	29284404	AR	2	designed research|conducted the experiments|wrote the manuscript, and all authors approved the manuscript	designed research	Conceived and designed the experiments	Methodology	YES
5747157	29284404	AR	2	designed research|conducted the experiments|wrote the manuscript, and all authors approved the manuscript	conducted the experiments	Performed the experiments	Investigation	YES
5747157	29284404	AR	2	designed research|conducted the experiments|wrote the manuscript, and all authors approved the manuscript	wrote the manuscript, and all authors approved the manuscript	Wrote the paper	Writing - Original Draft	YES
5747157	29284404	SG	2	conducted the experiments	conducted the experiments	Performed the experiments	Investigation	YES
5747157	29284404	SRP	2	designed research|wrote the manuscript, and all authors approved the manuscript	designed research	Conceived and designed the experiments	Methodology	YES
5747157	29284404	SRP	2	designed research|wrote the manuscript, and all authors approved the manuscript	wrote the manuscript, and all authors approved the manuscript	Wrote the paper	Writing - Original Draft	YES
4416803	25933295	CW	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416803	25933295	FX	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4416803	25933295	FX	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4416803	25933295	FX	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416803	25933295	HS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416803	25933295	HW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416803	25933295	HW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416803	25933295	HW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416803	25933295	LW	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416803	25933295	QZ	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4416803	25933295	QZ	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416803	25933295	RS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416803	25933295	RS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416803	25933295	RS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416803	25933295	SW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416803	25933295	YL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416803	25933295	YY	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4416803	25933295	YY	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416803	25933295	YZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5807348	29459879	BL	2	performed the experiment and wrote the draft manuscript|conceived and designed the project|worked on manuscript edition	performed the experiment and wrote the draft manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5807348	29459879	BL	2	performed the experiment and wrote the draft manuscript|conceived and designed the project|worked on manuscript edition	conceived and designed the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5807348	29459879	BL	2	performed the experiment and wrote the draft manuscript|conceived and designed the project|worked on manuscript edition	worked on manuscript edition	Performed the experiments|Wrote the paper	Writing - Review & Editing	YES
5807348	29459879	DG	2	supervised the project, contributed to the experimental design and to the interpretation of results and edited the manuscript	supervised the project, contributed to the experimental design and to the interpretation of results and edited the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Supervision|Writing - Review & Editing	YES
5807348	29459879	NDS	2	conceived and designed the project|worked on manuscript edition	conceived and designed the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5807348	29459879	NDS	2	conceived and designed the project|worked on manuscript edition	worked on manuscript edition	Performed the experiments|Wrote the paper	Writing - Review & Editing	YES
1964538	17849017	DL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1964538	17849017	DL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1964538	17849017	DL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1964538	17849017	DL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1964538	17849017	FV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1964538	17849017	FV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1964538	17849017	FV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1964538	17849017	FV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1964538	17849017	FV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1964538	17849017	JN	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1964538	17849017	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1964538	17849017	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1964538	17849017	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1964538	17849017	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1964538	17849017	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1964538	17849017	YS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1964538	17849017	YS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1964538	17849017	YS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1964538	17849017	YS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1964538	17849017	YS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270708	24786849	Hu-Biao Chen	2	who is providing fund for this research work, the design of the work and modified the paper	who is providing fund for this research work, the design of the work and modified the paper	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Funding acquisition|Investigation|Writing - Review & Editing	YES
6270708	24786849	Jian-Ye Zhang	2	who participated the research design, and the data analysis	who participated the research design, and the data analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis	YES
6270708	24786849	Jing Liu	2	who participated in the experiment work	who participated in the experiment work	Performed the experiments	Investigation	YES
6270708	24786849	Jun Xu	2	who participated in the research design, and modified the paper	who participated in the research design, and modified the paper	Conceived and designed the experiments|Wrote the paper	Writing - Review & Editing	YES
6270708	24786849	Tao Yi	2	who participated in the design of research and modified the paper	who participated in the design of research and modified the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
6270708	24786849	Xi-Chen He	2	who participated in the data analysis of lc-ms	who participated in the data analysis of lc-ms	Analyzed the data	Formal analysis	YES
6270708	24786849	Ya-Zhou Zhang	2	who presided the research work, finished the data analysis, and written this paper	who presided the research work, finished the data analysis, and written this paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6270708	24786849	Yi-Na Tang	2	who participated in the research design and data analysis	who participated in the research design and data analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis	YES
4416804	25932628	GK	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416804	25932628	GK	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416804	25932628	GK	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416804	25932628	HA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416804	25932628	HA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416804	25932628	HA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416804	25932628	HA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416804	25932628	NJ	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416804	25932628	NJ	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6068466	29907695	AZ	2	designed the experiments|made the cell lines and assisted with the ivm and cell migration analysis	designed the experiments	Conceived and designed the experiments	Methodology	YES
6068466	29907695	AZ	2	designed the experiments|made the cell lines and assisted with the ivm and cell migration analysis	made the cell lines and assisted with the ivm and cell migration analysis	Performed the experiments	Investigation	YES
6068466	29907695	CRJ	2	conceived and supervised the study|designed the experiments|wrote the manuscript, which was reviewed and approved by all authors	conceived and supervised the study	Conceived and designed the experiments	Conceptualization|Supervision	YES
6068466	29907695	CRJ	2	conceived and supervised the study|designed the experiments|wrote the manuscript, which was reviewed and approved by all authors	designed the experiments	Conceived and designed the experiments	Methodology	YES
6068466	29907695	CRJ	2	conceived and supervised the study|designed the experiments|wrote the manuscript, which was reviewed and approved by all authors	wrote the manuscript, which was reviewed and approved by all authors	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6068466	29907695	EC	2	performed quality control and gene expression analysis of transcriptomic data	performed quality control and gene expression analysis of transcriptomic data	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Validation	YES
6068466	29907695	JdL	2	performed quality control and gene expression analysis of transcriptomic data|wrote the manuscript, which was reviewed and approved by all authors	performed quality control and gene expression analysis of transcriptomic data	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Validation	YES
6068466	29907695	JdL	2	performed quality control and gene expression analysis of transcriptomic data|wrote the manuscript, which was reviewed and approved by all authors	wrote the manuscript, which was reviewed and approved by all authors	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6068466	29907695	JvR	2	designed the experiments|wrote the manuscript, which was reviewed and approved by all authors	designed the experiments	Conceived and designed the experiments	Methodology	YES
6068466	29907695	JvR	2	designed the experiments|wrote the manuscript, which was reviewed and approved by all authors	wrote the manuscript, which was reviewed and approved by all authors	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6068466	29907695	MS	2	protein identification, and label-free quantitation	protein identification, and label-free quantitation	Performed the experiments	Investigation	YES
6068466	29907695	RH	2	performed electron microscopy	performed electron microscopy	Performed the experiments	Investigation	YES
6068466	29907695	RMS	2	performed electron microscopy	performed electron microscopy	Performed the experiments	Investigation	YES
6068466	29907695	SCS	2	designed the experiments|performed most of the experiments|wrote the manuscript, which was reviewed and approved by all authors	designed the experiments	Conceived and designed the experiments	Methodology	YES
6068466	29907695	SCS	2	designed the experiments|performed most of the experiments|wrote the manuscript, which was reviewed and approved by all authors	performed most of the experiments	Performed the experiments	Investigation	YES
6068466	29907695	SCS	2	designed the experiments|performed most of the experiments|wrote the manuscript, which was reviewed and approved by all authors	wrote the manuscript, which was reviewed and approved by all authors	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6068466	29907695	SRP	2	wrote the manuscript, which was reviewed and approved by all authors	wrote the manuscript, which was reviewed and approved by all authors	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5634988	29019162	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5634988	29019162	CZG	2	hy analysis the data	hy analysis the data	Analyzed the data	Formal analysis	YES
5634988	29019162	HJG	2	performed the research study	performed the research study	Performed the experiments	Investigation	YES
5634988	29019162	HXG	2	designed the work|drafted the manuscript	designed the work	Conceived and designed the experiments	-	YES
5634988	29019162	HXG	2	designed the work|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5634988	29019162	JYW	2	performed the research study	performed the research study	Performed the experiments	Investigation	YES
5634988	29019162	LXL	2	performed the research study	performed the research study	Performed the experiments	Investigation	YES
5634988	29019162	MRS	2	hy analysis the data	hy analysis the data	Analyzed the data	Formal analysis	YES
5634988	29019162	QKZ	2	hy analysis the data	hy analysis the data	Analyzed the data	Formal analysis	YES
5634988	29019162	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5634988	29019162	YSQ	2	hy analysis the data	hy analysis the data	Analyzed the data	Formal analysis	YES
5634988	29019162	ZJK	2	performed the research study	performed the research study	Performed the experiments	Investigation	YES
5634988	29019162	ZYX	2	performed the research study	performed the research study	Performed the experiments	Investigation	YES
1964539	17849018	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1964539	17849018	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1964539	17849018	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1964539	17849018	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1964539	17849018	LT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1964539	17849018	LT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1964539	17849018	LT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1964539	17849018	LT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5747239	29284405	BB	2	contributed data and helped in the analyses	contributed data and helped in the analyses	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5747239	29284405	BG	2	conceived the study, carried out all analyses and wrote the manuscript	conceived the study, carried out all analyses and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
5747239	29284405	CF	2	contributed data and helped in the analyses	contributed data and helped in the analyses	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5747239	29284405	CS	2	contributed data and helped in the analyses	contributed data and helped in the analyses	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5747239	29284405	DG	2	contributed data and helped in the analyses	contributed data and helped in the analyses	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5747239	29284405	HH	2	contributed data and helped in the analyses	contributed data and helped in the analyses	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5747239	29284405	HP	2	conceived the study, carried out all analyses and wrote the manuscript	conceived the study, carried out all analyses and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
5747239	29284405	MF	2	conceived the study, carried out all analyses and wrote the manuscript	conceived the study, carried out all analyses and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
5747239	29284405	RF	2	contributed data and helped in the analyses	contributed data and helped in the analyses	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5807350	29459876	AC	2	performed the experiments, conducted the data analysis, and curated the data	performed the experiments, conducted the data analysis, and curated the data	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5807350	29459876	CC	2	provided the genetic resources and data|performed the experiments, conducted the data analysis, and curated the data	provided the genetic resources and data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5807350	29459876	CC	2	provided the genetic resources and data|performed the experiments, conducted the data analysis, and curated the data	performed the experiments, conducted the data analysis, and curated the data	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5807350	29459876	CH	2	provided the genetic resources and data	provided the genetic resources and data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5807350	29459876	JC	2	conceptualized the research and revised the manuscript|performed the experiments, conducted the data analysis, and curated the data|wrote the original draft and were responsible for the data visualization	conceptualized the research and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5807350	29459876	JC	2	conceptualized the research and revised the manuscript|performed the experiments, conducted the data analysis, and curated the data|wrote the original draft and were responsible for the data visualization	performed the experiments, conducted the data analysis, and curated the data	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5807350	29459876	JC	2	conceptualized the research and revised the manuscript|performed the experiments, conducted the data analysis, and curated the data|wrote the original draft and were responsible for the data visualization	wrote the original draft and were responsible for the data visualization	Analyzed the data|Wrote the paper	Visualization|Writing - Original Draft	YES
5807350	29459876	PO-A	2	conceptualized the research and revised the manuscript|administered the project	conceptualized the research and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5807350	29459876	PO-A	2	conceptualized the research and revised the manuscript|administered the project	administered the project	-	Project administration	YES
5807350	29459876	SB	2	performed the experiments, conducted the data analysis, and curated the data	performed the experiments, conducted the data analysis, and curated the data	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5807350	29459876	TI	2	provided the genetic resources and data	provided the genetic resources and data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5807350	29459876	YC	2	conceptualized the research and revised the manuscript|performed the experiments, conducted the data analysis, and curated the data|wrote the original draft and were responsible for the data visualization	conceptualized the research and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5807350	29459876	YC	2	conceptualized the research and revised the manuscript|performed the experiments, conducted the data analysis, and curated the data|wrote the original draft and were responsible for the data visualization	performed the experiments, conducted the data analysis, and curated the data	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5807350	29459876	YC	2	conceptualized the research and revised the manuscript|performed the experiments, conducted the data analysis, and curated the data|wrote the original draft and were responsible for the data visualization	wrote the original draft and were responsible for the data visualization	Analyzed the data|Wrote the paper	Visualization|Writing - Original Draft	YES
4901452	27269601	J.H.	2	designed experiments, aided in data analysis and wrote the manuscript	designed experiments, aided in data analysis and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4901452	27269601	P.C.	2	designed experiments, ran experiments, developed the models, analysed data and wrote the manuscript	designed experiments, ran experiments, developed the models, analysed data and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4416805	25932632	HH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416805	25932632	HH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416805	25932632	HH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416805	25932632	HH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416805	25932632	HH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416805	25932632	JR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416805	25932632	JR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416805	25932632	JR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416805	25932632	JR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416805	25932632	JR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416805	25932632	QZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416805	25932632	QZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416805	25932632	QZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416805	25932632	QZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416805	25932632	QZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416805	25932632	XZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416805	25932632	XZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416805	25932632	XZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416805	25932632	XZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416805	25932632	XZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416805	25932632	YL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416805	25932632	YL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416805	25932632	YL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416805	25932632	YL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270709	25338178	Alexander V. Ponomarev	PLoS52	carried out electron-beam experiments and analysis|generalized and analyzed data|wrote the paper	carried out electron-beam experiments and analysis	Performed the experiments	Investigation	YES
6270709	25338178	Alexander V. Ponomarev	PLoS52	carried out electron-beam experiments and analysis|generalized and analyzed data|wrote the paper	generalized and analyzed data	Analyzed the data	Formal analysis	YES
6270709	25338178	Alexander V. Ponomarev	PLoS52	carried out electron-beam experiments and analysis|generalized and analyzed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270709	25338178	Boris G. Ershov	PLoS52	prepared cellulose samples and reactionary equipment|generalized and analyzed data|wrote the paper	prepared cellulose samples and reactionary equipment	Performed the experiments	Investigation	YES
6270709	25338178	Boris G. Ershov	PLoS52	prepared cellulose samples and reactionary equipment|generalized and analyzed data|wrote the paper	generalized and analyzed data	Analyzed the data	Formal analysis	YES
6270709	25338178	Boris G. Ershov	PLoS52	prepared cellulose samples and reactionary equipment|generalized and analyzed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5634992	29019096	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5634992	29019096	FL	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5634992	29019096	FM	PLoS52	conceived and designed the study|reviewed and edited the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5634992	29019096	FM	PLoS52	conceived and designed the study|reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5634992	29019096	HC	PLoS52	conceived and designed the study|performed the experiments|wrote the paper|reviewed and edited the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5634992	29019096	HC	PLoS52	conceived and designed the study|performed the experiments|wrote the paper|reviewed and edited the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5634992	29019096	HC	PLoS52	conceived and designed the study|performed the experiments|wrote the paper|reviewed and edited the manuscript	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5634992	29019096	HC	PLoS52	conceived and designed the study|performed the experiments|wrote the paper|reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5634992	29019096	LTD	PLoS52	authors declare that they have no competing of interests	authors declare that they have no competing of interests	-	-	NO
5634992	29019096	WD	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5634992	29019096	YL	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5634992	29019096	YW	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5634992	29019096	Zhengzhou Yuwen	PLoS52	education consulting co	education consulting co	-	-	NO
6092621	30006452	ARW	2	performed ngs data analysis	performed ngs data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6092621	30006452	ASc	2	analyzed the tad protein sequences	analyzed the tad protein sequences	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6092621	30006452	ASt	2	conceived the project	conceived the project	Conceived and designed the experiments	Conceptualization	YES
6092621	30006452	AV	2	performed ngs data analysis	performed ngs data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6092621	30006452	CDA	2	conceived the project|conducted the experiments|analyzed data and prepared the figures	conceived the project	Conceived and designed the experiments	Conceptualization	YES
6092621	30006452	CDA	2	conceived the project|conducted the experiments|analyzed data and prepared the figures	conducted the experiments	Performed the experiments	Investigation	YES
6092621	30006452	CDA	2	conceived the project|conducted the experiments|analyzed data and prepared the figures	analyzed data and prepared the figures	Analyzed the data	Formal analysis|Visualization	YES
6092621	30006452	FN	2	conducted the experiments|analyzed data and prepared the figures	conducted the experiments	Performed the experiments	Investigation	YES
6092621	30006452	FN	2	conducted the experiments|analyzed data and prepared the figures	analyzed data and prepared the figures	Analyzed the data	Formal analysis|Visualization	YES
6092621	30006452	MP	2	helped with experiments	helped with experiments	Performed the experiments	Investigation	YES
6092621	30006452	MR	2	helped with experiments	helped with experiments	Performed the experiments	Investigation	YES
6092621	30006452	SW	2	conceived the project|conducted the experiments	conceived the project	Conceived and designed the experiments	Conceptualization	YES
6092621	30006452	SW	2	conceived the project|conducted the experiments	conducted the experiments	Performed the experiments	Investigation	YES
1964547	17848985	CB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1964547	17848985	CB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1964547	17848985	CB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1964547	17848985	CB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1964547	17848985	CB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1964547	17848985	SP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1964547	17848985	SP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1964547	17848985	SP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1964547	17848985	SP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1964547	17848985	SP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3167323	21263741	ALT	2	article drafting and critical revision for important intellectual content	article drafting and critical revision for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3167323	21263741	AT	2	article drafting and critical revision for important intellectual content	article drafting and critical revision for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3167323	21263741	CC	2	substantial contributions to conception and design, acquisition of data, or analysis and interpretation of data	substantial contributions to conception and design, acquisition of data, or analysis and interpretation of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
3167323	21263741	DM	2	substantial contributions to conception and design, acquisition of data, or analysis and interpretation of data|article drafting and critical revision for important intellectual content|final approval of the manuscript	substantial contributions to conception and design, acquisition of data, or analysis and interpretation of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
3167323	21263741	DM	2	substantial contributions to conception and design, acquisition of data, or analysis and interpretation of data|article drafting and critical revision for important intellectual content|final approval of the manuscript	article drafting and critical revision for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3167323	21263741	DM	2	substantial contributions to conception and design, acquisition of data, or analysis and interpretation of data|article drafting and critical revision for important intellectual content|final approval of the manuscript	final approval of the manuscript	-	-	NO
3167323	21263741	GD	2	article drafting and critical revision for important intellectual content	article drafting and critical revision for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3167323	21263741	MC	2	substantial contributions to conception and design, acquisition of data, or analysis and interpretation of data	substantial contributions to conception and design, acquisition of data, or analysis and interpretation of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
3167323	21263741	MM	2	article drafting and critical revision for important intellectual content	article drafting and critical revision for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3167323	21263741	TL	2	substantial contributions to conception and design, acquisition of data, or analysis and interpretation of data|article drafting and critical revision for important intellectual content|final approval of the manuscript	substantial contributions to conception and design, acquisition of data, or analysis and interpretation of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
3167323	21263741	TL	2	substantial contributions to conception and design, acquisition of data, or analysis and interpretation of data|article drafting and critical revision for important intellectual content|final approval of the manuscript	article drafting and critical revision for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3167323	21263741	TL	2	substantial contributions to conception and design, acquisition of data, or analysis and interpretation of data|article drafting and critical revision for important intellectual content|final approval of the manuscript	final approval of the manuscript	-	-	NO
4416806	25932942	HH	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416806	25932942	HH	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416806	25932942	HH	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416806	25932942	JH	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416806	25932942	JH	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416806	25932942	JH	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416806	25932942	NG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416806	25932942	NG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416806	25932942	NG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4901454	27269603	A.J.P.	2	conceived and designed the experiment	conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
4901454	27269603	All authors	2	were involved in the interpretation of data, in writing the paper, and have approved of the final version to be published	were involved in the interpretation of data, in writing the paper, and have approved of the final version to be published	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4901454	27269603	K.K.	2	conceived and designed the experiment	conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
4901454	27269603	T.L.C.	2	acquired and analysed all the data	acquired and analysed all the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
1964548	17848989	AW	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1964548	17848989	AW	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1964548	17848989	KL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1964548	17848989	LC	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1964548	17848989	LC	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1964548	17848989	LC	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1964548	17848989	TK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1964548	17848989	TK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1964548	17848989	TW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1964548	17848989	TW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1964548	17848989	TW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1964548	17848989	TW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1964548	17848989	YC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5807371	29459881	AK	2	conducted the data analyses and wrote the manuscript	conducted the data analyses and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5807371	29459881	L-HX	2	harvested the samples, and conducted the lipid and gene expression analyses	harvested the samples, and conducted the lipid and gene expression analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5807371	29459881	L-XN	2	designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
5807371	29459881	MR	2	conducted the data analyses and wrote the manuscript	conducted the data analyses and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5807371	29459881	Q-YZ	2	designed the research|harvested the samples, and conducted the lipid and gene expression analyses|conducted the data analyses and wrote the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
5807371	29459881	Q-YZ	2	designed the research|harvested the samples, and conducted the lipid and gene expression analyses|conducted the data analyses and wrote the manuscript	harvested the samples, and conducted the lipid and gene expression analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5807371	29459881	Q-YZ	2	designed the research|harvested the samples, and conducted the lipid and gene expression analyses|conducted the data analyses and wrote the manuscript	conducted the data analyses and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5807371	29459881	RY	2	harvested the samples, and conducted the lipid and gene expression analyses	harvested the samples, and conducted the lipid and gene expression analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5807371	29459881	Y-LZ	2	designed the research|conducted the data analyses and wrote the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
5807371	29459881	Y-LZ	2	designed the research|conducted the data analyses and wrote the manuscript	conducted the data analyses and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5748942	29291727	AJ	2	cultured the strains and extracted the genomic dna	cultured the strains and extracted the genomic dna	Performed the experiments	Investigation	YES
5748942	29291727	AN	2	conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5748942	29291727	All the authors	2	reviewed critically the manuscript and approved the final version	reviewed critically the manuscript and approved the final version	Wrote the paper	Writing - Review & Editing	YES
5748942	29291727	CR	2	conceived the study|developed the methodology|wrote the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5748942	29291727	CR	2	conceived the study|developed the methodology|wrote the manuscript	developed the methodology	Performed the experiments	Methodology	YES
5748942	29291727	CR	2	conceived the study|developed the methodology|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5748942	29291727	GG	2	performed the sequencing of strains and collected the data	performed the sequencing of strains and collected the data	Performed the experiments	Investigation	YES
5748942	29291727	GI	2	conceived the study|wrote the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5748942	29291727	GI	2	conceived the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5748942	29291727	HN	2	was in charge of the statistical analyses and assisted in the data analysis	was in charge of the statistical analyses and assisted in the data analysis	Analyzed the data	Formal analysis	YES
5748942	29291727	LB	2	conceived the study|developed the methodology|wrote the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5748942	29291727	LB	2	conceived the study|developed the methodology|wrote the manuscript	developed the methodology	Performed the experiments	Methodology	YES
5748942	29291727	LB	2	conceived the study|developed the methodology|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5748942	29291727	MCR	2	cultured the strains and extracted the genomic dna	cultured the strains and extracted the genomic dna	Performed the experiments	Investigation	YES
5748942	29291727	ML	2	conceived the study|developed the methodology|wrote the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5748942	29291727	ML	2	conceived the study|developed the methodology|wrote the manuscript	developed the methodology	Performed the experiments	Methodology	YES
5748942	29291727	ML	2	conceived the study|developed the methodology|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5748942	29291727	PF	2	conceived the study|developed the methodology|wrote the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5748942	29291727	PF	2	conceived the study|developed the methodology|wrote the manuscript	developed the methodology	Performed the experiments	Methodology	YES
5748942	29291727	PF	2	conceived the study|developed the methodology|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6092624	29967030	AS	2	performed all other experiments|planned the experiments, analysed data, and wrote the paper	performed all other experiments	Performed the experiments	Investigation	YES
6092624	29967030	AS	2	performed all other experiments|planned the experiments, analysed data, and wrote the paper	planned the experiments, analysed data, and wrote the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
6092624	29967030	CA	2	performed the mouse genetics and electrophysiological experiments|planned the experiments, analysed data, and wrote the paper	performed the mouse genetics and electrophysiological experiments	Performed the experiments	Investigation	YES
6092624	29967030	CA	2	performed the mouse genetics and electrophysiological experiments|planned the experiments, analysed data, and wrote the paper	planned the experiments, analysed data, and wrote the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
6092624	29967030	FL	2	planned the experiments, analysed data, and wrote the paper	planned the experiments, analysed data, and wrote the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
6092624	29967030	TCS	2	planned the experiments, analysed data, and wrote the paper	planned the experiments, analysed data, and wrote the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
6270710	25397735	AKB	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270710	25397735	AL	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270710	25397735	HK	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270710	25397735	OB	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5653677	29063373	DM	1	Manuscript drafting	Manuscript drafting	Wrote the paper	Writing - Original Draft	YES
5653677	29063373	HY	1	Planning and designing of study	Planning and designing of study	Conceived and designed the experiments	Methodology	YES
5653677	29063373	JF	1	Data analysis	Data analysis	Analyzed the data	Formal analysis	YES
5653677	29063373	XL	1	Planning and designing of study	Planning and designing of study	Conceived and designed the experiments	Methodology	YES
5653677	29063373	XZ	1	Experimentation	Experimentation	Performed the experiments	Investigation	YES
5653677	29063373	YL	1	Data analysis	Data analysis	Analyzed the data	Formal analysis	YES
5653677	29063373	YX	1	Experimentation|Data analysis|Manuscript drafting	Experimentation	Performed the experiments	Investigation	YES
5653677	29063373	YX	1	Experimentation|Data analysis|Manuscript drafting	Data analysis	Analyzed the data	Formal analysis	YES
5653677	29063373	YX	1	Experimentation|Data analysis|Manuscript drafting	Manuscript drafting	Wrote the paper	Writing - Original Draft	YES
4901455	27269604	A.J.P.	2	conceived and designed the analysis in this paper	conceived and designed the analysis in this paper	Conceived and designed the experiments	Conceptualization	YES
4901455	27269604	All authors	2	were involved in the interpretation of data, in writing the paper and have approved the final version to be published	were involved in the interpretation of data, in writing the paper and have approved the final version to be published	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4901455	27269604	J.S.	2	analysed the magnification factor for v5/mt	analysed the magnification factor for v5/mt	-	-	NO
4901455	27269604	K.K.	2	acquired and analysed the v5/mt data	acquired and analysed the v5/mt data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
1964802	17878932	RF	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1964802	17878932	RF	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1964802	17878932	TW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1964802	17878932	TW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1964802	17878932	TW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1964802	17878932	TW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5807375	29459877	CX	7	designed the research|provided the material	designed the research	Conceived and designed the experiments	Methodology	YES
5807375	29459877	CX	7	designed the research|provided the material	provided the material	Contributed reagents/materials/analysis tools	Resources	YES
5807375	29459877	FL	7	designed the research|did the cross work and phenotype evaluation|completed the molecular marker and cytological analysis|wrote the paper	designed the research	Conceived and designed the experiments	Methodology	YES
5807375	29459877	FL	7	designed the research|did the cross work and phenotype evaluation|completed the molecular marker and cytological analysis|wrote the paper	did the cross work and phenotype evaluation	Performed the experiments	Investigation	YES
5807375	29459877	FL	7	designed the research|did the cross work and phenotype evaluation|completed the molecular marker and cytological analysis|wrote the paper	completed the molecular marker and cytological analysis	Performed the experiments	Investigation	YES
5807375	29459877	FL	7	designed the research|did the cross work and phenotype evaluation|completed the molecular marker and cytological analysis|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5807375	29459877	LC	7	did the cross work and phenotype evaluation|completed the molecular marker and cytological analysis	did the cross work and phenotype evaluation	Performed the experiments	Investigation	YES
5807375	29459877	LC	7	did the cross work and phenotype evaluation|completed the molecular marker and cytological analysis	completed the molecular marker and cytological analysis	Performed the experiments	Investigation	YES
5807375	29459877	LQ	7	did the cross work and phenotype evaluation	did the cross work and phenotype evaluation	Performed the experiments	Investigation	YES
5807375	29459877	MG	7	did the cross work and phenotype evaluation	did the cross work and phenotype evaluation	Performed the experiments	Investigation	YES
5807375	29459877	PL	7	did the cross work and phenotype evaluation	did the cross work and phenotype evaluation	Performed the experiments	Investigation	YES
5807375	29459877	QS	7	provided the material	provided the material	Contributed reagents/materials/analysis tools	Resources	YES
5807375	29459877	QZ	7	did the cross work and phenotype evaluation	did the cross work and phenotype evaluation	Performed the experiments	Investigation	YES
5807375	29459877	YL	7	did the cross work and phenotype evaluation	did the cross work and phenotype evaluation	Performed the experiments	Investigation	YES
4416808	25933289	BX	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416808	25933289	DG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416808	25933289	DG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416808	25933289	DG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416808	25933289	HL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416808	25933289	LW	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416808	25933289	LW	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416808	25933289	LW	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416808	25933289	LW	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416808	25933289	SQ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416808	25933289	X. Li	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416808	25933289	X. Li	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416808	25933289	X. Li	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416808	25933289	X. Li	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416808	25933289	X. Lu	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416808	25933289	YW	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416808	25933289	YY	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5748962	29291709	D.L.	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5748962	29291709	J.W.	2	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5748962	29291709	L. Zhang	2	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5748962	29291709	L. Zhao	2	performed experiments|wrote the manuscript	performed experiments	Performed the experiments	Investigation	YES
5748962	29291709	L. Zhao	2	performed experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5748962	29291709	M.H.	2	planned and designed the research|wrote the manuscript	planned and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5748962	29291709	M.H.	2	planned and designed the research|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5748962	29291709	S.N.	2	planned and designed the research|performed experiments	planned and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5748962	29291709	S.N.	2	planned and designed the research|performed experiments	performed experiments	Performed the experiments	Investigation	YES
5748962	29291709	Y.Y.	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5748962	29291709	Y.Z.	2	planned and designed the research	planned and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5748962	29291709	Z.Y.	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
6092677	29991564	AP	2	performed animal experiments|performed molecular experiments	performed animal experiments	Performed the experiments	Investigation	YES
6092677	29991564	AP	2	performed animal experiments|performed molecular experiments	performed molecular experiments	Performed the experiments	Investigation	YES
6092677	29991564	CD	2	performed animal experiments	performed animal experiments	Performed the experiments	Investigation	YES
6092677	29991564	DB	2	conceived and designed immunological experiments|performed animal experiments|performed molecular experiments|performed rna seq experiment|wrote the manuscript	conceived and designed immunological experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6092677	29991564	DB	2	conceived and designed immunological experiments|performed animal experiments|performed molecular experiments|performed rna seq experiment|wrote the manuscript	performed animal experiments	Performed the experiments	Investigation	YES
6092677	29991564	DB	2	conceived and designed immunological experiments|performed animal experiments|performed molecular experiments|performed rna seq experiment|wrote the manuscript	performed molecular experiments	Performed the experiments	Investigation	YES
6092677	29991564	DB	2	conceived and designed immunological experiments|performed animal experiments|performed molecular experiments|performed rna seq experiment|wrote the manuscript	performed rna seq experiment	Performed the experiments	Investigation	YES
6092677	29991564	DB	2	conceived and designed immunological experiments|performed animal experiments|performed molecular experiments|performed rna seq experiment|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6092677	29991564	MO	2	conceived the tocky strategies and the project|conceived and designed immunological experiments|wrote computational codes, and performed bioinformatics analysis and data visualisation|wrote the manuscript	conceived the tocky strategies and the project	Conceived and designed the experiments	Conceptualization	YES
6092677	29991564	MO	2	conceived the tocky strategies and the project|conceived and designed immunological experiments|wrote computational codes, and performed bioinformatics analysis and data visualisation|wrote the manuscript	conceived and designed immunological experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6092677	29991564	MO	2	conceived the tocky strategies and the project|conceived and designed immunological experiments|wrote computational codes, and performed bioinformatics analysis and data visualisation|wrote the manuscript	wrote computational codes, and performed bioinformatics analysis and data visualisation	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Formal analysis|Investigation|Software|Visualization|Writing - Original Draft	YES
6092677	29991564	MO	2	conceived the tocky strategies and the project|conceived and designed immunological experiments|wrote computational codes, and performed bioinformatics analysis and data visualisation|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6092677	29991564	PPM	2	performed animal experiments	performed animal experiments	Performed the experiments	Investigation	YES
6092677	29991564	TC	2	conceived and designed immunological experiments|wrote the manuscript	conceived and designed immunological experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6092677	29991564	TC	2	conceived and designed immunological experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4901456	27269605	G.B.	PLoS52	carried out the behavioural experiments	carried out the behavioural experiments	Performed the experiments	Investigation	YES
4901456	27269605	G.T.	PLoS52	programmed the stimuli for all experiments	programmed the stimuli for all experiments	Contributed reagents/materials/analysis tools	Software	YES
4901456	27269605	J.R.	PLoS52	designed the behavioural experiments|wrote the paper	designed the behavioural experiments	Conceived and designed the experiments	Methodology	YES
4901456	27269605	J.R.	PLoS52	designed the behavioural experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4901456	27269605	V.N.	PLoS52	designed the behavioural experiments|carried out the behavioural experiments|analysed the behavioural experiments|wrote the paper	designed the behavioural experiments	Conceived and designed the experiments	Methodology	YES
4901456	27269605	V.N.	PLoS52	designed the behavioural experiments|carried out the behavioural experiments|analysed the behavioural experiments|wrote the paper	carried out the behavioural experiments	Performed the experiments	Investigation	YES
4901456	27269605	V.N.	PLoS52	designed the behavioural experiments|carried out the behavioural experiments|analysed the behavioural experiments|wrote the paper	analysed the behavioural experiments	-	-	NO
4901456	27269605	V.N.	PLoS52	designed the behavioural experiments|carried out the behavioural experiments|analysed the behavioural experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
1964803	17849000	DP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1964803	17849000	DP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1964803	17849000	DP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1964803	17849000	DP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1964803	17849000	JL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed and analyzed height-dbh data|Contributed to development of model and statistics	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1964803	17849000	JL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed and analyzed height-dbh data|Contributed to development of model and statistics	Analyzed the data	Analyzed the data	Formal analysis	YES
1964803	17849000	JL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed and analyzed height-dbh data|Contributed to development of model and statistics	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1964803	17849000	JL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed and analyzed height-dbh data|Contributed to development of model and statistics	Contributed and analyzed height-dbh data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
1964803	17849000	JL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed and analyzed height-dbh data|Contributed to development of model and statistics	Contributed to development of model and statistics	Performed the experiments|Analyzed the data	Formal analysis|Methodology	YES
1964803	17849000	SP	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1964803	17849000	SP	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416809	25933118	HZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416809	25933118	HZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416809	25933118	HZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416809	25933118	HZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416809	25933118	JY	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4416809	25933118	JY	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416809	25933118	LZ	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416809	25933118	RL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416809	25933118	RL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416809	25933118	RL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416809	25933118	RM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4416809	25933118	RM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416809	25933118	SS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416809	25933118	SS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416809	25933118	XZ	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4416809	25933118	XZ	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5655377	29067567	All	2	data are fully available without restriction	data are fully available without restriction	-	-	NO
5655377	29067567	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5655377	29067567	CF	2	helped to perform zeta potential measurements	helped to perform zeta potential measurements	Performed the experiments	Investigation	YES
5655377	29067567	CJ	2	participated in the drafting and reviewing of the manuscript, analyzed the data and contributed to the statistical analysis	participated in the drafting and reviewing of the manuscript, analyzed the data and contributed to the statistical analysis	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5655377	29067567	MA	2	participated in the drafting and reviewing of the manuscript, analyzed the data and contributed to the statistical analysis	participated in the drafting and reviewing of the manuscript, analyzed the data and contributed to the statistical analysis	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5655377	29067567	NEC	2	supervised and provided important intellectual content in the research design, coordination of the study and contributed in the drafting of the manuscript	supervised and provided important intellectual content in the research design, coordination of the study and contributed in the drafting of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Supervision|Writing - Original Draft	YES
5655377	29067567	RB	2	participated in the determination of the cytotoxic effects of supernatant samples	participated in the determination of the cytotoxic effects of supernatant samples	-	-	NO
5655377	29067567	SOK	2	performed all measurements and experiments and drafted the manuscript	performed all measurements and experiments and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5655377	29067567	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5807407	29459874	AS	7	conceptualized, edited and approved the final manuscript	conceptualized, edited and approved the final manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5807407	29459874	DS	7	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5807407	29459874	DV	7	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5807407	29459874	KS	7	prepared figures	prepared figures	-	Visualization	YES
5807407	29459874	PB	7	wrote the manuscript|prepared figures	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5807407	29459874	PB	7	wrote the manuscript|prepared figures	prepared figures	-	Visualization	YES
5807407	29459874	SJ	7	wrote the manuscript|conceptualize the overall structure, prepared the illustrations, and edited the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5807407	29459874	SJ	7	wrote the manuscript|conceptualize the overall structure, prepared the illustrations, and edited the manuscript	conceptualize the overall structure, prepared the illustrations, and edited the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Visualization|Writing - Original Draft|Writing - Review & Editing	YES
5807407	29459874	SN	7	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5807407	29459874	ST	7	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4637019	26583088	Marilisa Molinaro	2	share first authorship	share first authorship	-	-	NO
4637019	26583088	Pietro Ameri	2	share first authorship	share first authorship	-	-	NO
5748963	29291734	JR	2	designed the research, obtained funding, helped with interpretation of results, and wrote the manuscript	designed the research, obtained funding, helped with interpretation of results, and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Funding acquisition|Methodology|Writing - Original Draft	YES
5748963	29291734	LPC	2	provided guidance on computational analysis of the gbs sequence data, conducted data analysis, and wrote the manuscript	provided guidance on computational analysis of the gbs sequence data, conducted data analysis, and wrote the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Supervision|Writing - Original Draft	YES
5748963	29291734	ZA	2	conducted dna extractions, data analysis, and wrote the manuscript	conducted dna extractions, data analysis, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6120658	29987118	AS	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
6120658	29987118	DZ	2	generated reagents	generated reagents	Performed the experiments	Investigation	YES
6120658	29987118	LAA	2	carried out the experiments|wrote the manuscript	carried out the experiments	Performed the experiments	Investigation	YES
6120658	29987118	LAA	2	carried out the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6120658	29987118	PRC	2	wrote the manuscript|supervised the study	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6120658	29987118	PRC	2	wrote the manuscript|supervised the study	supervised the study	-	Supervision	YES
1964804	17849012	JB	PLoS5	Performed the experiments|Wrote the paper|Recruited participants|Collected data	Performed the experiments	Performed the experiments	Investigation	YES
1964804	17849012	JB	PLoS5	Performed the experiments|Wrote the paper|Recruited participants|Collected data	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1964804	17849012	JB	PLoS5	Performed the experiments|Wrote the paper|Recruited participants|Collected data	Recruited participants	Performed the experiments	Investigation	YES
1964804	17849012	JB	PLoS5	Performed the experiments|Wrote the paper|Recruited participants|Collected data	Collected data	Performed the experiments	Investigation	YES
1964804	17849012	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Designed the study|Recruited participants|Collected data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1964804	17849012	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Designed the study|Recruited participants|Collected data	Performed the experiments	Performed the experiments	Investigation	YES
1964804	17849012	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Designed the study|Recruited participants|Collected data	Analyzed the data	Analyzed the data	Formal analysis	YES
1964804	17849012	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Designed the study|Recruited participants|Collected data	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1964804	17849012	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Designed the study|Recruited participants|Collected data	Designed the study	Conceived and designed the experiments	Methodology	YES
1964804	17849012	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Designed the study|Recruited participants|Collected data	Recruited participants	Performed the experiments	Investigation	YES
1964804	17849012	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Designed the study|Recruited participants|Collected data	Collected data	Performed the experiments	Investigation	YES
1964804	17849012	SB	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1964804	17849012	SB	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1964804	17849012	SC	PLoS5	Designed the study	Designed the study	Conceived and designed the experiments	Methodology	YES
1964804	17849012	SW	PLoS5	Conceived and designed the experiments|Wrote the paper|Designed the study	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1964804	17849012	SW	PLoS5	Conceived and designed the experiments|Wrote the paper|Designed the study	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1964804	17849012	SW	PLoS5	Conceived and designed the experiments|Wrote the paper|Designed the study	Designed the study	Conceived and designed the experiments	Methodology	YES
4901457	27269606	A.E.W.	2	conceived and designed the study|analysed and interpreted the data|revised and edited the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4901457	27269606	A.E.W.	2	conceived and designed the study|analysed and interpreted the data|revised and edited the manuscript	analysed and interpreted the data	Analyzed the data	Formal analysis	YES
4901457	27269606	A.E.W.	2	conceived and designed the study|analysed and interpreted the data|revised and edited the manuscript	revised and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
4901457	27269606	A.P.M.	2	conceived and designed the study|performed experiments and wrote the manuscript|analysed and interpreted the data	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4901457	27269606	A.P.M.	2	conceived and designed the study|performed experiments and wrote the manuscript|analysed and interpreted the data	performed experiments and wrote the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4901457	27269606	A.P.M.	2	conceived and designed the study|performed experiments and wrote the manuscript|analysed and interpreted the data	analysed and interpreted the data	Analyzed the data	Formal analysis	YES
4901457	27269606	D.A.L.	2	conceived and designed the study|revised and edited the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4901457	27269606	D.A.L.	2	conceived and designed the study|revised and edited the manuscript	revised and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
4901457	27269606	G.W.H.	2	conceived and designed the study|revised and edited the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4901457	27269606	G.W.H.	2	conceived and designed the study|revised and edited the manuscript	revised and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
4416810	25932999	AC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416810	25932999	AD	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416810	25932999	AD	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416810	25932999	AD	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416810	25932999	AG	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416810	25932999	CI	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416810	25932999	CI	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416810	25932999	CS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416810	25932999	DS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416810	25932999	EA	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4416810	25932999	EA	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416810	25932999	ED	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416810	25932999	ED	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416810	25932999	ED	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416810	25932999	ED	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416810	25932999	MML	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416810	25932999	NM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416810	25932999	PP	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416810	25932999	RB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416810	25932999	RR	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416810	25932999	SP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416810	25932999	TP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5662524	29086199	ALL	2	performed research and wrote the manuscript	performed research and wrote the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5662524	29086199	All	2	datasets supporting the conclusions of the manuscript were included in the article	datasets supporting the conclusions of the manuscript were included in the article	-	-	NO
5662524	29086199	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5662524	29086199	JW	2	participated in the in vitro antiviral experiments	participated in the in vitro antiviral experiments	Performed the experiments	Investigation	YES
5662524	29086199	JYZ	2	participated in the design of the study	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
5662524	29086199	LZ	2	collected and analyzed data	collected and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5662524	29086199	MZX	2	prepared the tissue sections	prepared the tissue sections	Performed the experiments	Investigation	YES
5662524	29086199	SQG	2	collected and analyzed data|participated in the design of the study	collected and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5662524	29086199	SQG	2	collected and analyzed data|participated in the design of the study	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
5662524	29086199	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5662524	29086199	WBL	2	prepared the tissue sections	prepared the tissue sections	Performed the experiments	Investigation	YES
5662524	29086199	XBJ	2	participated in the design of the study	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
5662524	29086199	XML	2	performed research and wrote the manuscript	performed research and wrote the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5662524	29086199	YNT	2	participated in the in vitro antiviral experiments	participated in the in vitro antiviral experiments	Performed the experiments	Investigation	YES
5662524	29086199	ZXC	2	participated in the in vitro antiviral experiments	participated in the in vitro antiviral experiments	Performed the experiments	Investigation	YES
6270713	25093981	AM	2	helped to perform research and draft the manuscript	helped to perform research and draft the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6270713	25093981	MN	2	designed research, performed research, analyzed the data and wrote the manuscript	designed research, performed research, analyzed the data and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
6270713	25093981	RN	2	performed research, analyzed the data and wrote the manuscript	performed research, analyzed the data and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3167329	21263742	BM	2	conceived and designed the experiments, analyzed the data, wrote the manuscript	conceived and designed the experiments, analyzed the data, wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
3167329	21263742	CG	2	conceived and designed the experiments, acquisition of data, performed the experiments, analyzed the data, wrote the manuscript	conceived and designed the experiments, acquisition of data, performed the experiments, analyzed the data, wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
3167329	21263742	DF	2	conceived and designed the experiments, acquisition of data, performed the experiments, analyzed the data, wrote the manuscript	conceived and designed the experiments, acquisition of data, performed the experiments, analyzed the data, wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
3167329	21263742	FC	2	designed and performed the experiments, contributed reagents/materials/analysis tools	designed and performed the experiments, contributed reagents/materials/analysis tools	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources	YES
3167329	21263742	GF	2	conceived, designed and performed the experiments, analyzed the data, wrote the manuscript, critical revision of the manuscript and approval of the article	conceived, designed and performed the experiments, analyzed the data, wrote the manuscript, critical revision of the manuscript and approval of the article	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
3167329	21263742	IM	2	conceived and designed the experiments, performed the experiments, analyzed the data, wrote the manuscript, critical revision of the manuscript and approval of the article	conceived and designed the experiments, performed the experiments, analyzed the data, wrote the manuscript, critical revision of the manuscript and approval of the article	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
3167329	21263742	MC	2	conceived, designed and performed the experiments, analyzed the data, wrote the manuscript, critical revision of the manuscript and approval of the article	conceived, designed and performed the experiments, analyzed the data, wrote the manuscript, critical revision of the manuscript and approval of the article	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
3167329	21263742	MF	2	designed and performed the experiments, contributed reagents/materials/analysis tools	designed and performed the experiments, contributed reagents/materials/analysis tools	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources	YES
3167329	21263742	SN	2	conceived and designed the experiments, acquisition of data, performed the experiments, analyzed the data, wrote the manuscript	conceived and designed the experiments, acquisition of data, performed the experiments, analyzed the data, wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
3167329	21263742	TC	2	designed the experiments, analyzed the data, wrote the manuscript	designed the experiments, analyzed the data, wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5807412	29459880	All authors	PLoS52	agreed on the contents of the paper and declared that no competing interests exist	agreed on the contents of the paper and declared that no competing interests exist	-	-	NO
5807412	29459880	CK	PLoS52	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5807412	29459880	J-HK	PLoS52	conceived and designed the experiments|performed the experiments and analyzed the data|revised the draft	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5807412	29459880	J-HK	PLoS52	conceived and designed the experiments|performed the experiments and analyzed the data|revised the draft	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5807412	29459880	J-HK	PLoS52	conceived and designed the experiments|performed the experiments and analyzed the data|revised the draft	revised the draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5807412	29459880	KC	PLoS52	collected the plant materials	collected the plant materials	Performed the experiments	Investigation	YES
5807412	29459880	Y-HH	PLoS52	collected the plant materials|performed the experiments and analyzed the data	collected the plant materials	Performed the experiments	Investigation	YES
5807412	29459880	Y-HH	PLoS52	collected the plant materials|performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6120664	30049712	AO	1	Intellectual input	Intellectual input	-	-	NO
6120664	30049712	APW	1	Experimental work|Data analysis	Experimental work	Performed the experiments	Investigation	YES
6120664	30049712	APW	1	Experimental work|Data analysis	Data analysis	Analyzed the data	Formal analysis	YES
6120664	30049712	CC	1	Experimental work	Experimental work	Performed the experiments	Investigation	YES
6120664	30049712	GQ	1	Development and contribution of reagents|Intellectual input	Development and contribution of reagents	Contributed reagents/materials/analysis tools	Resources	YES
6120664	30049712	GQ	1	Development and contribution of reagents|Intellectual input	Intellectual input	-	-	NO
6120664	30049712	HS	1	Development and contribution of reagents	Development and contribution of reagents	Contributed reagents/materials/analysis tools	Resources	YES
6120664	30049712	JC	1	Experimental work|Data analysis	Experimental work	Performed the experiments	Investigation	YES
6120664	30049712	JC	1	Experimental work|Data analysis	Data analysis	Analyzed the data	Formal analysis	YES
6120664	30049712	JFP	1	Experimental work|Intellectual input	Experimental work	Performed the experiments	Investigation	YES
6120664	30049712	JFP	1	Experimental work|Intellectual input	Intellectual input	-	-	NO
6120664	30049712	JL	1	Development and contribution of reagents	Development and contribution of reagents	Contributed reagents/materials/analysis tools	Resources	YES
6120664	30049712	JOP	1	Development and contribution of reagents	Development and contribution of reagents	Contributed reagents/materials/analysis tools	Resources	YES
6120664	30049712	JSR	1	Experimental work|Data analysis|Intellectual input|Manuscript writing	Experimental work	Performed the experiments	Investigation	YES
6120664	30049712	JSR	1	Experimental work|Data analysis|Intellectual input|Manuscript writing	Data analysis	Analyzed the data	Formal analysis	YES
6120664	30049712	JSR	1	Experimental work|Data analysis|Intellectual input|Manuscript writing	Intellectual input	-	-	NO
6120664	30049712	JSR	1	Experimental work|Data analysis|Intellectual input|Manuscript writing	Manuscript writing	Wrote the paper	Writing - Original Draft	YES
6120664	30049712	KMR	1	Development and contribution of reagents	Development and contribution of reagents	Contributed reagents/materials/analysis tools	Resources	YES
6120664	30049712	LMC	1	Intellectual input	Intellectual input	-	-	NO
6120664	30049712	MP	1	Experimental work	Experimental work	Performed the experiments	Investigation	YES
6120664	30049712	SWGT	1	Data analysis|Intellectual input|Manuscript writing	Data analysis	Analyzed the data	Formal analysis	YES
6120664	30049712	SWGT	1	Data analysis|Intellectual input|Manuscript writing	Intellectual input	-	-	NO
6120664	30049712	SWGT	1	Data analysis|Intellectual input|Manuscript writing	Manuscript writing	Wrote the paper	Writing - Original Draft	YES
4637020	26583096	All authors	PLoS52	contributed to the interpretation of results and discussion and read, corrected, and approved the final paper	contributed to the interpretation of results and discussion and read, corrected, and approved the final paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4637020	26583096	Anisoara Cimpean	PLoS52	conceived the study|directed the study|wrote the paper	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4637020	26583096	Anisoara Cimpean	PLoS52	conceived the study|directed the study|wrote the paper	directed the study	-	Supervision	YES
4637020	26583096	Anisoara Cimpean	PLoS52	conceived the study|directed the study|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4637020	26583096	Cora Vasilescu	PLoS52	studied the electrochemical behaviour and corrosion resistance of analyzed biomaterials	studied the electrochemical behaviour and corrosion resistance of analyzed biomaterials	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4637020	26583096	Doina-Margareta Gordin	PLoS52	conceived the study|performed the synthesis of the alloy samples and the superficial nitriding treatments|directed the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4637020	26583096	Doina-Margareta Gordin	PLoS52	conceived the study|performed the synthesis of the alloy samples and the superficial nitriding treatments|directed the study	performed the synthesis of the alloy samples and the superficial nitriding treatments	Performed the experiments	Investigation	YES
4637020	26583096	Doina-Margareta Gordin	PLoS52	conceived the study|performed the synthesis of the alloy samples and the superficial nitriding treatments|directed the study	directed the study	-	Supervision	YES
4637020	26583096	Mariana-Cristina Tabirca	PLoS52	performed the synthesis of the alloy samples and the superficial nitriding treatments	performed the synthesis of the alloy samples and the superficial nitriding treatments	Performed the experiments	Investigation	YES
4637020	26583096	Petre Osiceanu	PLoS52	performed xps complete analysis	performed xps complete analysis	Performed the experiments	Investigation	YES
4637020	26583096	Silviu Iulian Drob	PLoS52	studied the electrochemical behaviour and corrosion resistance of analyzed biomaterials	studied the electrochemical behaviour and corrosion resistance of analyzed biomaterials	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4637020	26583096	Thierry Gloriant	PLoS52	conceived the study|directed the study|wrote the paper	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4637020	26583096	Thierry Gloriant	PLoS52	conceived the study|directed the study|wrote the paper	directed the study	-	Supervision	YES
4637020	26583096	Thierry Gloriant	PLoS52	conceived the study|directed the study|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4637020	26583096	Valentina Mitran	PLoS52	performed biological experiments and prepared the figures	performed biological experiments and prepared the figures	Performed the experiments	Investigation|Visualization	YES
1964805	17849013	CD	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1964805	17849013	CD	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1964805	17849013	EL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1964805	17849013	EL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1964805	17849013	EL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1964805	17849013	HF	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1964805	17849013	HF	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1964805	17849013	HW	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1964805	17849013	HW	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1964805	17849013	JY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1964805	17849013	JY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1964805	17849013	JY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1964805	17849013	JY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5749029	29291715	AP	2	generated high quality genome annotations	generated high quality genome annotations	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5749029	29291715	All authors	2	interpreted the results and reviewed and approved the final manuscript	interpreted the results and reviewed and approved the final manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5749029	29291715	BB	2	generated genome assemblies, worked on the primary sequence and wrote manuscript	generated genome assemblies, worked on the primary sequence and wrote manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5749029	29291715	CC	2	performed whole genome comparisons and identified mobile genomic elements	performed whole genome comparisons and identified mobile genomic elements	Performed the experiments	Investigation	YES
5749029	29291715	CS	2	did long read sequencing	did long read sequencing	Performed the experiments	Investigation	YES
5749029	29291715	DW	2	performed motility assays	performed motility assays	Performed the experiments	Investigation	YES
5749029	29291715	EB	2	analyzed data, wrote manuscript	analyzed data, wrote manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5749029	29291715	HL	2	designed research, analyzed genomic data and wrote manuscript	designed research, analyzed genomic data and wrote manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5749029	29291715	JO	2	designed research and wrote manuscript	designed research and wrote manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5749029	29291715	KG	2	performed sporulation experiments, antibiotic assay, co-cultivation assays and analyzed data	performed sporulation experiments, antibiotic assay, co-cultivation assays and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5749029	29291715	OZ	2	isolated strains and did growth experiments	isolated strains and did growth experiments	Performed the experiments	Investigation	YES
5749029	29291715	RD	2	designed research and wrote manuscript	designed research and wrote manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5749029	29291715	TEM	2	images and analyzed flagellum locus	images and analyzed flagellum locus	Analyzed the data	Formal analysis|Visualization	YES
5749029	29291715	TR	2	generated genome assemblies, worked on the primary sequence and wrote manuscript	generated genome assemblies, worked on the primary sequence and wrote manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5749029	29291715	UG	2	designed research, provided strains, wrote manuscript	designed research, provided strains, wrote manuscript	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Methodology|Resources|Writing - Original Draft	YES
5749029	29291715	WB	2	performed sporulation assays	performed sporulation assays	Performed the experiments	Investigation	YES
5668215	29098480	All authors	PLoS52	revised the manuscript, participated in discussion of the manuscript and agreed to the final content|read and approved the final manuscript	revised the manuscript, participated in discussion of the manuscript and agreed to the final content	Wrote the paper	Writing - Review & Editing	YES
5668215	29098480	All authors	PLoS52	revised the manuscript, participated in discussion of the manuscript and agreed to the final content|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5668215	29098480	GZ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5668215	29098480	MR	PLoS52	carried out the data analysis and prepared the first draft of the manuscript	carried out the data analysis and prepared the first draft of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5668215	29098480	MX	PLoS52	were responsible for the library preparation and sample sequencing	were responsible for the library preparation and sample sequencing	Performed the experiments	Investigation	YES
5668215	29098480	TL	PLoS52	conceived the study and designed the experiments	conceived the study and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5668215	29098480	YL	PLoS52	were responsible for the library preparation and sample sequencing	were responsible for the library preparation and sample sequencing	Performed the experiments	Investigation	YES
5668215	29098480	ZQ	PLoS52	were responsible for the library preparation and sample sequencing	were responsible for the library preparation and sample sequencing	Performed the experiments	Investigation	YES
5668215	29098480	ZY	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
6270714	25237755	ATP	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
6270714	25237755	FB	PLoS52	designed research|analyzed the data|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
6270714	25237755	FB	PLoS52	designed research|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
6270714	25237755	FB	PLoS52	designed research|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270714	25237755	IMG	PLoS52	designed research|performed research|analyzed the data	designed research	Conceived and designed the experiments	Methodology	YES
6270714	25237755	IMG	PLoS52	designed research|performed research|analyzed the data	performed research	Performed the experiments	Investigation	YES
6270714	25237755	IMG	PLoS52	designed research|performed research|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
6270714	25237755	LP	PLoS52	designed research|analyzed the data|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
6270714	25237755	LP	PLoS52	designed research|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
6270714	25237755	LP	PLoS52	designed research|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270714	25237755	MA	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
6270714	25237755	SR	PLoS52	designed research|analyzed the data|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
6270714	25237755	SR	PLoS52	designed research|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
6270714	25237755	SR	PLoS52	designed research|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416812	25933025	MX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416812	25933025	MX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416812	25933025	MX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416812	25933025	MX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416812	25933025	RK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416812	25933025	RK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416812	25933025	RK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416812	25933025	TH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416812	25933025	TH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416812	25933025	TH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416812	25933025	YX	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416812	25933025	YZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1964806	17849003	AW	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1964806	17849003	EJ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1964806	17849003	HH	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1964806	17849003	HU	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1964806	17849003	IA	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1964806	17849003	IM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1964806	17849003	KJ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1964806	17849003	LO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1964806	17849003	LO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1964806	17849003	LO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1964806	17849003	LO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1964806	17849003	ML	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1964806	17849003	OA	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1964806	17849003	SD	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1964806	17849003	ST	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1964806	17849003	TH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1964806	17849003	TH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1964806	17849003	TH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1964806	17849003	TH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1964806	17849003	TW	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4920289	27298463	All authors	2	participated in the interpretation of results	participated in the interpretation of results	Analyzed the data	Formal analysis	YES
4920289	27298463	D.P.	2	updated bovid data and provided critical references	updated bovid data and provided critical references	-	-	NO
4920289	27298463	F.B.	2	updated bovid data and provided critical references to earlier work	updated bovid data and provided critical references to earlier work	-	-	NO
4920289	27298463	J.R.	2	cleaned and updated the dataset and implemented the stratigraphy that was used for the analyses	cleaned and updated the dataset and implemented the stratigraphy that was used for the analyses	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
4920289	27298463	L.L.	2	conducted and supervised fieldwork that generated the data used	conducted and supervised fieldwork that generated the data used	Performed the experiments	Investigation|Supervision	YES
4920289	27298463	L.W.	2	updated the carnivore data, conducted the turnover analyses and co-wrote the final manuscript	updated the carnivore data, conducted the turnover analyses and co-wrote the final manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
4920289	27298463	M.L.	2	conducted and supervised fieldwork that generated the data used to build the new database and updated primate data	conducted and supervised fieldwork that generated the data used to build the new database and updated primate data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software|Supervision	YES
4920289	27298463	R.B.	2	compiled the original database that we complemented for this study, updated bovid data and co-wrote the final manuscript	compiled the original database that we complemented for this study, updated bovid data and co-wrote the final manuscript	Contributed reagents/materials/analysis tools|Wrote the paper	Data curation|Software|Writing - Original Draft|Writing - Review & Editing	YES
6120666	30026309	AD	CRediT	Conceptualization|Writing--original draft|Funding acquisition	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6120666	30026309	AD	CRediT	Conceptualization|Writing--original draft|Funding acquisition	Writing--original draft	Wrote the paper	Writing - Original Draft	YES
6120666	30026309	AD	CRediT	Conceptualization|Writing--original draft|Funding acquisition	Funding acquisition	-	Funding acquisition	YES
6120666	30026309	ANB	CRediT	Conceptualization|Funding acquisition	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6120666	30026309	ANB	CRediT	Conceptualization|Funding acquisition	Funding acquisition	-	Funding acquisition	YES
6120666	30026309	BD	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
6120666	30026309	CR	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
6120666	30026309	CS	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
6120666	30026309	DMP	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
6120666	30026309	GDC	CRediT	Conceptualization|Funding acquisition	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6120666	30026309	GDC	CRediT	Conceptualization|Funding acquisition	Funding acquisition	-	Funding acquisition	YES
6120666	30026309	JAW	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
6120666	30026309	JCB	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
6120666	30026309	KVMH	CRediT	Methodology|Funding acquisition	Methodology	Performed the experiments	Methodology	YES
6120666	30026309	KVMH	CRediT	Methodology|Funding acquisition	Funding acquisition	-	Funding acquisition	YES
6120666	30026309	LS	CRediT	Investigation|Writing--original draft	Investigation	Performed the experiments	Investigation	YES
6120666	30026309	LS	CRediT	Investigation|Writing--original draft	Writing--original draft	Wrote the paper	Writing - Original Draft	YES
6120666	30026309	MG-H	CRediT	Conceptualization|Writing--original draft|Funding acquisition	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6120666	30026309	MG-H	CRediT	Conceptualization|Writing--original draft|Funding acquisition	Writing--original draft	Wrote the paper	Writing - Original Draft	YES
6120666	30026309	MG-H	CRediT	Conceptualization|Writing--original draft|Funding acquisition	Funding acquisition	-	Funding acquisition	YES
6120666	30026309	MH	CRediT	Investigation|Writing--original draft	Investigation	Performed the experiments	Investigation	YES
6120666	30026309	MH	CRediT	Investigation|Writing--original draft	Writing--original draft	Wrote the paper	Writing - Original Draft	YES
6120666	30026309	PF	CRediT	Methodology	Methodology	Performed the experiments	Methodology	YES
6120666	30026309	SN	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
6120666	30026309	SP	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
5751606	29295711	BG	2	conceived the experiment	conceived the experiment	Conceived and designed the experiments	Conceptualization	YES
5751606	29295711	CZ	2	designed and conducted the experiments|conducted data analysis and drafted the manuscript	designed and conducted the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5751606	29295711	CZ	2	designed and conducted the experiments|conducted data analysis and drafted the manuscript	conducted data analysis and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5751606	29295711	GZ	2	designed and conducted the experiments|revised the manuscript	designed and conducted the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5751606	29295711	GZ	2	designed and conducted the experiments|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5751606	29295711	HZ	2	contributed to the experiments and data analysis	contributed to the experiments and data analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5751606	29295711	JG	2	conceived the experiment	conceived the experiment	Conceived and designed the experiments	Conceptualization	YES
5751606	29295711	KW	2	contributed to the experiments and data analysis	contributed to the experiments and data analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5751606	29295711	SL	2	contributed to the experiments and data analysis	contributed to the experiments and data analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5751606	29295711	ZG	2	conducted data analysis and drafted the manuscript	conducted data analysis and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5751606	29295711	ZW	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5807415	29459875	The authors	2	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	Performed the experiments	Investigation	YES
1964807	17878934	JM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1964807	17878934	LG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1964807	17878934	LG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1964807	17878934	LG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1964807	17878934	PS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1964807	17878934	PS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1964807	17878934	PS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1964807	17878934	PS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416813	25933113	AF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416813	25933113	AF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416813	25933113	AF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416813	25933113	AF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416813	25933113	AF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416813	25933113	CL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416813	25933113	CL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416813	25933113	CL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416813	25933113	CL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416813	25933113	CL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416813	25933113	EE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416813	25933113	EE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416813	25933113	EE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416813	25933113	EE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416813	25933113	EE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416813	25933113	ES	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416813	25933113	ES	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416813	25933113	ES	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416813	25933113	ES	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416813	25933113	ES	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416813	25933113	LH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416813	25933113	LH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416813	25933113	LH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416813	25933113	LH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416813	25933113	LH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416813	25933113	UM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416813	25933113	UM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416813	25933113	UM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416813	25933113	UM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416813	25933113	UM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5668220	29098440	All	2	datasets were presented in the main paper	datasets were presented in the main paper	-	-	NO
5668220	29098440	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5668220	29098440	JEC	2	designed the study, analyzed and interpreted the data, and wrote the manuscript	designed the study, analyzed and interpreted the data, and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5668220	29098440	MEHL	2	designed the study, analyzed and interpreted the data, and wrote the manuscript	designed the study, analyzed and interpreted the data, and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5668220	29098440	MTAZ	2	conducted the study and collected the data, created figures|designed the study, analyzed and interpreted the data, and wrote the manuscript	conducted the study and collected the data, created figures	Performed the experiments	Investigation|Visualization	YES
5668220	29098440	MTAZ	2	conducted the study and collected the data, created figures|designed the study, analyzed and interpreted the data, and wrote the manuscript	designed the study, analyzed and interpreted the data, and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5668220	29098440	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5807426	29459878	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5807426	29459878	BU	PLoS52	conducted the experiments|performed the histology experiments	conducted the experiments	Performed the experiments	Investigation	YES
5807426	29459878	BU	PLoS52	conducted the experiments|performed the histology experiments	performed the histology experiments	Performed the experiments	Investigation	YES
5807426	29459878	GD	PLoS52	conceived and designed the study|conducted the experiments|measured the amino acid profiles|analyzed the data	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5807426	29459878	GD	PLoS52	conceived and designed the study|conducted the experiments|measured the amino acid profiles|analyzed the data	conducted the experiments	Performed the experiments	Investigation	YES
5807426	29459878	GD	PLoS52	conceived and designed the study|conducted the experiments|measured the amino acid profiles|analyzed the data	measured the amino acid profiles	Performed the experiments	Investigation	YES
5807426	29459878	GD	PLoS52	conceived and designed the study|conducted the experiments|measured the amino acid profiles|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5807426	29459878	GV	PLoS52	conducted the experiments|performed the histology experiments	conducted the experiments	Performed the experiments	Investigation	YES
5807426	29459878	GV	PLoS52	conducted the experiments|performed the histology experiments	performed the histology experiments	Performed the experiments	Investigation	YES
5807426	29459878	IB	PLoS52	performed the histology experiments	performed the histology experiments	Performed the experiments	Investigation	YES
5807426	29459878	IL	PLoS52	measured the amino acid profiles	measured the amino acid profiles	Performed the experiments	Investigation	YES
5807426	29459878	KZ	PLoS52	conceived and designed the study|conducted the experiments|managed and evaluated the insect populations|drafted the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5807426	29459878	KZ	PLoS52	conceived and designed the study|conducted the experiments|managed and evaluated the insect populations|drafted the manuscript	conducted the experiments	Performed the experiments	Investigation	YES
5807426	29459878	KZ	PLoS52	conceived and designed the study|conducted the experiments|managed and evaluated the insect populations|drafted the manuscript	managed and evaluated the insect populations	-	-	NO
5807426	29459878	KZ	PLoS52	conceived and designed the study|conducted the experiments|managed and evaluated the insect populations|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5807426	29459878	MM	PLoS52	conducted the experiments|managed and evaluated the insect populations	conducted the experiments	Performed the experiments	Investigation	YES
5807426	29459878	MM	PLoS52	conducted the experiments|managed and evaluated the insect populations	managed and evaluated the insect populations	-	-	NO
5807426	29459878	SG	PLoS52	conceived and designed the study|measured the amino acid profiles|analyzed the data	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5807426	29459878	SG	PLoS52	conceived and designed the study|measured the amino acid profiles|analyzed the data	measured the amino acid profiles	Performed the experiments	Investigation	YES
5807426	29459878	SG	PLoS52	conceived and designed the study|measured the amino acid profiles|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5807426	29459878	VB	PLoS52	measured the amino acid profiles	measured the amino acid profiles	Performed the experiments	Investigation	YES
5751871	29295704	CTW	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5751871	29295704	GJK	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5751871	29295704	HDQ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5751871	29295704	RZZ	PLoS52	conceived and designed the experiments|analyzed the data|wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5751871	29295704	RZZ	PLoS52	conceived and designed the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5751871	29295704	RZZ	PLoS52	conceived and designed the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5751871	29295704	YHW	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5751871	29295704	YL	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5751871	29295704	ZYN	PLoS52	performed the experiments|analyzed the data|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5751871	29295704	ZYN	PLoS52	performed the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5751871	29295704	ZYN	PLoS52	performed the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4637023	26583091	Bei Zhang	2	contributed equally to this work	contributed equally to this work	-	-	NO
4637023	26583091	Shengnuo Fan	2	contributed equally to this work	contributed equally to this work	-	-	NO
1964808	17878938	LP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1964808	17878938	LP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1964808	17878938	LP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1964808	17878938	LP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1964808	17878938	MH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the study|Wrote the first draft of the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1964808	17878938	MH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the study|Wrote the first draft of the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1964808	17878938	MH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the study|Wrote the first draft of the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1964808	17878938	MH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the study|Wrote the first draft of the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1964808	17878938	MH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the study|Wrote the first draft of the paper	Designed the study	Conceived and designed the experiments	Methodology	YES
1964808	17878938	MH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the study|Wrote the first draft of the paper	Wrote the first draft of the paper	Wrote the paper	Writing - Original Draft	YES
1964808	17878938	NA	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1964808	17878938	NA	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1964808	17878938	NA	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1964808	17878938	NK	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1964808	17878938	NK	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1964808	17878938	NK	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1964808	17878938	RD	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1964808	17878938	RD	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1964808	17878938	RD	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1964808	17878938	RM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1964808	17878938	RM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1964808	17878938	RM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1964808	17878938	RM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1964808	17878938	SC	PLoS5	Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1964808	17878938	SC	PLoS5	Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1964808	17878938	SC	PLoS5	Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1964808	17878938	SC	PLoS5	Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1964808	17878938	SC	PLoS5	Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1964808	17878938	WS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1964808	17878938	WS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
3042593	21147546	C. Falkeis	2	prepared, performed and analyzed immunohistochemical stainings	prepared, performed and analyzed immunohistochemical stainings	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3042593	21147546	G. Sprinzl	2	revised the manuscript critically for important intellectual content	revised the manuscript critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
3042593	21147546	H. Riechelmann	2	participated in the design of the study|have done statistical analysis|revised the manuscript critically for important intellectual content	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
3042593	21147546	H. Riechelmann	2	participated in the design of the study|have done statistical analysis|revised the manuscript critically for important intellectual content	have done statistical analysis	Analyzed the data	Formal analysis	YES
3042593	21147546	H. Riechelmann	2	participated in the design of the study|have done statistical analysis|revised the manuscript critically for important intellectual content	revised the manuscript critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
3042593	21147546	J. Dudas	2	performed cell culture, western blot, gene expression, and immunocytochemical experiments|have done statistical analysis|have drafted the manuscript	performed cell culture, western blot, gene expression, and immunocytochemical experiments	Performed the experiments	Investigation	YES
3042593	21147546	J. Dudas	2	performed cell culture, western blot, gene expression, and immunocytochemical experiments|have done statistical analysis|have drafted the manuscript	have done statistical analysis	Analyzed the data	Formal analysis	YES
3042593	21147546	J. Dudas	2	performed cell culture, western blot, gene expression, and immunocytochemical experiments|have done statistical analysis|have drafted the manuscript	have drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
3042593	21147546	M. Bitsche	2	prepared, performed and analyzed immunohistochemical stainings	prepared, performed and analyzed immunohistochemical stainings	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3042593	21147546	M. Bitshe	2	performed cell culture, western blot, gene expression, and immunocytochemical experiments	performed cell culture, western blot, gene expression, and immunocytochemical experiments	Performed the experiments	Investigation	YES
3042593	21147546	M. Sprinzl	2	participated in the design of the study	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
3042593	21147546	V. Schartinger	2	prepared, performed and analyzed immunohistochemical stainings|have done statistical analysis|revised the manuscript critically for important intellectual content	prepared, performed and analyzed immunohistochemical stainings	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3042593	21147546	V. Schartinger	2	prepared, performed and analyzed immunohistochemical stainings|have done statistical analysis|revised the manuscript critically for important intellectual content	have done statistical analysis	Analyzed the data	Formal analysis	YES
3042593	21147546	V. Schartinger	2	prepared, performed and analyzed immunohistochemical stainings|have done statistical analysis|revised the manuscript critically for important intellectual content	revised the manuscript critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5668224	29098449	All	2	of the data are presented in the main paper or additional file 1	of the data are presented in the main paper or additional file 1	-	-	NO
5668224	29098449	All authors	2	read and approved the final manuscript|gave their consent for publication	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5668224	29098449	All authors	2	read and approved the final manuscript|gave their consent for publication	gave their consent for publication	-	-	NO
5668224	29098449	JC	2	designed and conducted the experiments, evaluated the results and drafted the manuscript	designed and conducted the experiments, evaluated the results and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5668224	29098449	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5668224	29098449	XJ	2	designed and conducted the study and drafted the manuscript	designed and conducted the study and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5668224	29098449	XL	2	designed and conducted the study and drafted the manuscript	designed and conducted the study and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
4416815	25933030	AC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4416815	25933030	AC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416815	25933030	AT	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416815	25933030	AT	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416815	25933030	CH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416815	25933030	CH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416815	25933030	CH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416815	25933030	CH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416815	25933030	EH	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416815	25933030	EH	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416815	25933030	EH	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416815	25933030	GD	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416815	25933030	GP	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416815	25933030	MR	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416815	25933030	MR	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416815	25933030	PN	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4416815	25933030	PN	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416815	25933030	TT	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5807883	29467774	AR	4	The trials were carried out by|Experiments were designed by RU and the data was analyzed by|The manuscript was written by	The trials were carried out by	Performed the experiments	Investigation	YES
5807883	29467774	AR	4	The trials were carried out by|Experiments were designed by RU and the data was analyzed by|The manuscript was written by	Experiments were designed by RU and the data was analyzed by	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5807883	29467774	AR	4	The trials were carried out by|Experiments were designed by RU and the data was analyzed by|The manuscript was written by	The manuscript was written by	Wrote the paper	Writing - Original Draft	YES
5807883	29467774	WB	4	The trials were carried out by|revised by RU and approved by	The trials were carried out by	Performed the experiments	Investigation	YES
5807883	29467774	WB	4	The trials were carried out by|revised by RU and approved by	revised by RU and approved by	Wrote the paper	Writing - Review & Editing	YES
5807883	29467774	YH	4	The trials were carried out by|Experiments were designed by RU and the data was analyzed by	The trials were carried out by	Performed the experiments	Investigation	YES
5807883	29467774	YH	4	The trials were carried out by|Experiments were designed by RU and the data was analyzed by	Experiments were designed by RU and the data was analyzed by	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
6138439	30154076	AMal	2	designed, performed the crispr/cas9-based genome-wide screen and the clonogenic experiments, and analyzed the data	designed, performed the crispr/cas9-based genome-wide screen and the clonogenic experiments, and analyzed the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
6138439	30154076	AMar	2	designed the experiments and analyzed the data	designed the experiments and analyzed the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
6138439	30154076	AO	2	conceived the study, designed the research, provided supervision, and wrote the manuscript with input from all the other authors	conceived the study, designed the research, provided supervision, and wrote the manuscript with input from all the other authors	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Supervision|Writing - Original Draft	YES
6138439	30154076	AS	2	designed and performed the comet assay experiments and analyzed the data	designed and performed the comet assay experiments and analyzed the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
6138439	30154076	CD	2	performed the ms experiments and analyzed the data under the	performed the ms experiments and analyzed the data under the	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6138439	30154076	CMG	2	supervised the performed the rna seq analysis and the patient cohort analysis under the	supervised the performed the rna seq analysis and the patient cohort analysis under the	Performed the experiments	Investigation|Supervision	YES
6138439	30154076	DG	2	performed the ms experiments and analyzed the data under the	performed the ms experiments and analyzed the data under the	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6138439	30154076	DR	2	performed the phylogenetic analysis profiling under the	performed the phylogenetic analysis profiling under the	Performed the experiments	Investigation	YES
6138439	30154076	EGL	2	performed the ms experiments and analyzed the data under the	performed the ms experiments and analyzed the data under the	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6138439	30154076	ES-C	2	performed the ms experiments and analyzed the data under the	performed the ms experiments and analyzed the data under the	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6138439	30154076	HB	2	performed the ms experiments and analyzed the data under the	performed the ms experiments and analyzed the data under the	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6138439	30154076	HKh	2	performed the ms experiments and analyzed the data under the	performed the ms experiments and analyzed the data under the	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6138439	30154076	HKu	2	performed the rna seq analysis and the patient cohort analysis under the	performed the rna seq analysis and the patient cohort analysis under the	Performed the experiments	Investigation	YES
6138439	30154076	J-FC	2	supervised the performed the ms experiments and analyzed the data under the	supervised the performed the ms experiments and analyzed the data under the	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Supervision	YES
6138439	30154076	J-YM	2	supervised the and performed the in vitro dna binding assays under the	supervised the and performed the in vitro dna binding assays under the	Performed the experiments	Investigation|Supervision	YES
6138439	30154076	JH	2	designed, performed most of the experiments presented in this manuscript, and analyzed the data	designed, performed most of the experiments presented in this manuscript, and analyzed the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
6138439	30154076	KKM	2	performed the pathway analysis of shld2	performed the pathway analysis of shld2	Performed the experiments	Investigation	YES
6138439	30154076	KOK	2	performed the rna seq analysis and the patient cohort analysis under the	performed the rna seq analysis and the patient cohort analysis under the	Performed the experiments	Investigation	YES
6138439	30154076	MK	2	performed the initial characterization of shdl2 in the foki system	performed the initial characterization of shdl2 in the foki system	Performed the experiments	Investigation	YES
6138439	30154076	MP	2	provided the rna seq data and the related patient outcome of the tnbc cohort	provided the rna seq data and the related patient outcome of the tnbc cohort	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
6138439	30154076	SF	2	designed, performed most of the experiments presented in this manuscript, and analyzed the data	designed, performed most of the experiments presented in this manuscript, and analyzed the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
6138439	30154076	VML	2	designed and performed the csr experiments and analyzed the data	designed and performed the csr experiments and analyzed the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
6138439	30154076	YC	2	purified recombinant shld2 and performed the in vitro dna binding assays under the	purified recombinant shld2 and performed the in vitro dna binding assays under the	Performed the experiments	Investigation	YES
6138439	30154076	YT	2	supervised the performed the phylogenetic analysis profiling under the	supervised the performed the phylogenetic analysis profiling under the	Performed the experiments	Investigation|Supervision	YES
6138439	30154076	ZL	2	generated most of the constructs used in this manuscript, designed and performed the chip experiments, and analyzed the data	generated most of the constructs used in this manuscript, designed and performed the chip experiments, and analyzed the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
6270717	24858097	Mehrnoush Amid	PLoS52	performed all the experiments|helped in interpretation of data and discussion of results|wrote the paper	performed all the experiments	Performed the experiments	Investigation	YES
6270717	24858097	Mehrnoush Amid	PLoS52	performed all the experiments|helped in interpretation of data and discussion of results|wrote the paper	helped in interpretation of data and discussion of results	Analyzed the data	Formal analysis	YES
6270717	24858097	Mehrnoush Amid	PLoS52	performed all the experiments|helped in interpretation of data and discussion of results|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270717	24858097	Nor Khanani Zohdi	PLoS52	performed all the experiments|wrote the paper	performed all the experiments	Performed the experiments	Investigation	YES
6270717	24858097	Nor Khanani Zohdi	PLoS52	performed all the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270717	24858097	Yazid Manap	PLoS52	helped in interpretation of data and discussion of results	helped in interpretation of data and discussion of results	Analyzed the data	Formal analysis	YES
5751882	29295707	BMK	2	analyzed data and wrote the paper	analyzed data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5751882	29295707	BYL	2	analyzed data and wrote the paper	analyzed data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5751882	29295707	DHK	2	analyzed data and wrote the paper	analyzed data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5751882	29295707	HSK	2	analyzed data and wrote the paper	analyzed data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5751882	29295707	JH	2	discussed all the issues during experiment and finally confirmed the manuscript	discussed all the issues during experiment and finally confirmed the manuscript	-	-	NO
5751882	29295707	JSL	2	discussed all the issues during experiment and finally confirmed the manuscript	discussed all the issues during experiment and finally confirmed the manuscript	-	-	NO
1964809	17849002	DD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1964809	17849002	DD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1964809	17849002	DD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1964809	17849002	DD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1964809	17849002	DD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1964809	17849002	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1964809	17849002	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1964809	17849002	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1964809	17849002	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1964809	17849002	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416816	25933092	AB	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416816	25933092	ADV	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416816	25933092	AMS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416816	25933092	EB	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416816	25933092	EC	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4416816	25933092	EC	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416816	25933092	MAP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416816	25933092	MAP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416816	25933092	MAP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416816	25933092	MF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416816	25933092	MF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416816	25933092	MF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416816	25933092	MF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416816	25933092	MJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416816	25933092	MJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416816	25933092	MJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416816	25933092	MJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416816	25933092	MM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416816	25933092	SL	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5668226	29098477	AKY	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
5668226	29098477	AKY	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5668226	29098477	AKY	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5668226	29098477	MPS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5668226	29098477	MR	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
5668226	29098477	MR	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5668226	29098477	NKS	PLoS5	Conceived and designed the experiment|Contributed reagents/materials/analysis tools	Conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5668226	29098477	NKS	PLoS5	Conceived and designed the experiment|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5668226	29098477	PS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5668226	29098477	SS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
5668226	29098477	SS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5668226	29098477	SS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4920333	27325829	M.P.	2	gathered the data and provided the palaeontological expertise behind the present analysis	gathered the data and provided the palaeontological expertise behind the present analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4920333	27325829	N.L.	2	designed the mixed clock model, implemented the monte carlo methods, applied the model to empirical data and performed the simulation study|wrote the first draft of the manuscript	designed the mixed clock model, implemented the monte carlo methods, applied the model to empirical data and performed the simulation study	Conceived and designed the experiments|Performed the experiments	Formal analysis|Investigation|Methodology	YES
4920333	27325829	N.L.	2	designed the mixed clock model, implemented the monte carlo methods, applied the model to empirical data and performed the simulation study|wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
6138442	30143514	All authors	2	contributed to data analysis and commented on the manuscript	contributed to data analysis and commented on the manuscript	Analyzed the data	Formal analysis	YES
6138442	30143514	GHS	2	wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
6138442	30143514	KKJ	2	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
6138442	30143514	SKR	2	wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
6138442	30143514	SS	2	supervised experimental work	supervised experimental work	Performed the experiments	Investigation|Supervision	YES
5808118	29467788	BZ	2	performed all of the experiments|analyzed the data and wrote the manuscript	performed all of the experiments	Performed the experiments	Investigation	YES
5808118	29467788	BZ	2	performed all of the experiments|analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5808118	29467788	JR	2	analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5808118	29467788	XZ	2	provided the experimental materials	provided the experimental materials	Contributed reagents/materials/analysis tools	Resources	YES
5808118	29467788	YL	2	designed the study|analyzed the data and wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5808118	29467788	YL	2	designed the study|analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5808118	29467788	YP	2	analyzed the data and wrote the manuscript|provided the experimental materials	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5808118	29467788	YP	2	analyzed the data and wrote the manuscript|provided the experimental materials	provided the experimental materials	Contributed reagents/materials/analysis tools	Resources	YES
5808118	29467788	YY	2	performed all of the experiments|analyzed the data and wrote the manuscript	performed all of the experiments	Performed the experiments	Investigation	YES
5808118	29467788	YY	2	performed all of the experiments|analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
1964878	17849014	AB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1964878	17849014	AB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1964878	17849014	AC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1964878	17849014	DH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1964878	17849014	MG	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1964878	17849014	MG	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1964878	17849014	MG	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1964878	17849014	NC	PLoS5	Performed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1964878	17849014	NC	PLoS5	Performed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1964878	17849014	NC	PLoS5	Performed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1964878	17849014	NC	PLoS5	Performed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1964878	17849014	PM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1964878	17849014	PM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1964878	17849014	PM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416817	25932910	AG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416817	25932910	AG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416817	25932910	AG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416817	25932910	AS	PLoS5	Contributed reagents/materials/analysis tools|Provided an additional statistical tool for improved visualization of the results of the enrichment and depletion analyses	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416817	25932910	AS	PLoS5	Contributed reagents/materials/analysis tools|Provided an additional statistical tool for improved visualization of the results of the enrichment and depletion analyses	Provided an additional statistical tool for improved visualization of the results of the enrichment and depletion analyses	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources|Visualization	YES
4416817	25932910	EW	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416817	25932910	EW	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416817	25932910	HB	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416817	25932910	JP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416817	25932910	JP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416817	25932910	JP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416817	25932910	JP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416817	25932910	SK	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4416817	25932910	SK	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416817	25932910	TC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416817	25932910	TC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416817	25932910	TC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416817	25932910	TG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416817	25932910	VS	PLoS5	Contributed reagents/materials/analysis tools|Designed the software used in the enrichment and depletion analyses	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416817	25932910	VS	PLoS5	Contributed reagents/materials/analysis tools|Designed the software used in the enrichment and depletion analyses	Designed the software used in the enrichment and depletion analyses	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Software	YES
4416817	25932910	VZ	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416817	25932910	VZ	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416817	25932910	VZ	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5753437	29298676	HT	2	wrote the manuscript with contributions from all coauthors	wrote the manuscript with contributions from all coauthors	Wrote the paper	Writing - Original Draft	YES
6270718	25230125	Hai-Zhen Zhu	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
6270718	25230125	Jiang-Hong An	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
6270718	25230125	Quan Yao	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
6270718	25230125	Zheng-Tang Chen	2	coordinated the research team	coordinated the research team	-	Project administration	YES
4637026	26583101	Anthony Fleury	2	contributed equally to this work	contributed equally to this work	-	-	NO
4637026	26583101	Bruno Diot	2	contributed equally to this work	contributed equally to this work	-	-	NO
4637026	26583101	Celine Franco	2	contributed equally to this work	contributed equally to this work	-	-	NO
4637026	26583101	Nicolas Vuillerme	2	contributed equally to this work	contributed equally to this work	-	-	NO
4920334	27325830	A.T.	2	provided scripts for dataset assembly and helped writing the manuscript	provided scripts for dataset assembly and helped writing the manuscript	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Software|Writing - Original Draft	YES
4920334	27325830	DP	2	contributed to all steps of the analyses and to writing the manuscript	contributed to all steps of the analyses and to writing the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4920334	27325830	G.E.	2	contributed to write the manuscript	contributed to write the manuscript	Wrote the paper	Writing - Original Draft	YES
4920334	27325830	G.G.	2	contributed to write the manuscript	contributed to write the manuscript	Wrote the paper	Writing - Original Draft	YES
4920334	27325830	J.L.-F.	2	carried out analyses and wrote the manuscript	carried out analyses and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4920334	27325830	J.O.	2	provided data and helped writing the manuscript	provided data and helped writing the manuscript	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Original Draft	YES
4920334	27325830	J.V.	2	provided data and helped writing the manuscript	provided data and helped writing the manuscript	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Original Draft	YES
4920334	27325830	M.B.	2	provided data and helped writing the manuscript	provided data and helped writing the manuscript	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Original Draft	YES
4920334	27325830	M.P.	2	carried out ancestral character state reconstruction and helped writing the manuscript	carried out ancestral character state reconstruction and helped writing the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4920334	27325830	R.C.	2	assembled the dataset and helped writing the manuscript	assembled the dataset and helped writing the manuscript	Wrote the paper	Writing - Original Draft	YES
1964879	17878930	CC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1964879	17878930	DB	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1964879	17878930	DB	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1964879	17878930	DW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1964879	17878930	KS	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1964879	17878930	MC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1964879	17878930	PL	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1964879	17878930	PL	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1964879	17878930	RJ	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1964879	17878930	SA	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1964879	17878930	SA	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1964879	17878930	SA	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1964879	17878930	TL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
6166124	30087110	AK	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
6166124	30087110	CR	2	provided human samples	provided human samples	Contributed reagents/materials/analysis tools	Resources	YES
6166124	30087110	DM	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
6166124	30087110	DP	2	performed experiments|planned experiments	performed experiments	Performed the experiments	Investigation	YES
6166124	30087110	DP	2	performed experiments|planned experiments	planned experiments	Conceived and designed the experiments	Conceptualization	YES
6166124	30087110	EP	2	performed statistical analysis	performed statistical analysis	Analyzed the data	Formal analysis	YES
6166124	30087110	EYL	2	performed bioinformatics analysis	performed bioinformatics analysis	Performed the experiments	Formal analysis|Investigation	YES
6166124	30087110	HF	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
6166124	30087110	JZ	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
6166124	30087110	KM	2	planned experiments|evaluated data	planned experiments	Conceived and designed the experiments	Conceptualization	YES
6166124	30087110	KM	2	planned experiments|evaluated data	evaluated data	-	-	NO
6166124	30087110	LC	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
6166124	30087110	LR	2	provided human samples	provided human samples	Contributed reagents/materials/analysis tools	Resources	YES
6166124	30087110	MFJ	2	planned experiments|evaluated data|wrote the manuscript	planned experiments	Conceived and designed the experiments	Conceptualization	YES
6166124	30087110	MFJ	2	planned experiments|evaluated data|wrote the manuscript	evaluated data	-	-	NO
6166124	30087110	MFJ	2	planned experiments|evaluated data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6166124	30087110	MHA	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
6166124	30087110	MJ	2	performed experiments|planned experiments|evaluated data|wrote the manuscript	performed experiments	Performed the experiments	Investigation	YES
6166124	30087110	MJ	2	performed experiments|planned experiments|evaluated data|wrote the manuscript	planned experiments	Conceived and designed the experiments	Conceptualization	YES
6166124	30087110	MJ	2	performed experiments|planned experiments|evaluated data|wrote the manuscript	evaluated data	-	-	NO
6166124	30087110	MJ	2	performed experiments|planned experiments|evaluated data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6166124	30087110	MSi	2	planned experiments	planned experiments	Conceived and designed the experiments	Conceptualization	YES
6166124	30087110	MSt	2	performed experiments|planned experiments|evaluated data	performed experiments	Performed the experiments	Investigation	YES
6166124	30087110	MSt	2	performed experiments|planned experiments|evaluated data	planned experiments	Conceived and designed the experiments	Conceptualization	YES
6166124	30087110	MSt	2	performed experiments|planned experiments|evaluated data	evaluated data	-	-	NO
6166124	30087110	RB	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
6166124	30087110	SF	2	planned experiments|evaluated data	planned experiments	Conceived and designed the experiments	Conceptualization	YES
6166124	30087110	SF	2	planned experiments|evaluated data	evaluated data	-	-	NO
6166124	30087110	SPR	2	performed experiments|planned experiments	performed experiments	Performed the experiments	Investigation	YES
6166124	30087110	SPR	2	performed experiments|planned experiments	planned experiments	Conceived and designed the experiments	Conceptualization	YES
6166124	30087110	TDM	2	performed bioinformatics analysis	performed bioinformatics analysis	Performed the experiments	Formal analysis|Investigation	YES
6166124	30087110	TK-R	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
6166124	30087110	VG-D	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
6166124	30087110	WFG	2	planned experiments	planned experiments	Conceived and designed the experiments	Conceptualization	YES
6166124	30087110	XS	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5673865	29110104	All	2	data generated or analysed during this study are included in this published article	data generated or analysed during this study are included in this published article	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5673865	29110104	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5673865	29110104	DFL	2	designed the experiments|analyzed the results	designed the experiments	Conceived and designed the experiments	Methodology	YES
5673865	29110104	DFL	2	designed the experiments|analyzed the results	analyzed the results	Analyzed the data	Formal analysis	YES
5673865	29110104	NH	2	designed the experiments|analyzed the results|wrote the manuscript which was reviewed and approved by all authors	designed the experiments	Conceived and designed the experiments	Methodology	YES
5673865	29110104	NH	2	designed the experiments|analyzed the results|wrote the manuscript which was reviewed and approved by all authors	analyzed the results	Analyzed the data	Formal analysis	YES
5673865	29110104	NH	2	designed the experiments|analyzed the results|wrote the manuscript which was reviewed and approved by all authors	wrote the manuscript which was reviewed and approved by all authors	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5673865	29110104	PZL	2	analyzed the results|wrote the manuscript which was reviewed and approved by all authors	analyzed the results	Analyzed the data	Formal analysis	YES
5673865	29110104	PZL	2	analyzed the results|wrote the manuscript which was reviewed and approved by all authors	wrote the manuscript which was reviewed and approved by all authors	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5673865	29110104	TM	2	preformed the experiments|wrote the manuscript which was reviewed and approved by all authors	preformed the experiments	Performed the experiments	Investigation	YES
5673865	29110104	TM	2	preformed the experiments|wrote the manuscript which was reviewed and approved by all authors	wrote the manuscript which was reviewed and approved by all authors	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5673865	29110104	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5673865	29110104	YPW	2	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5673865	29110104	ZC	2	designed the experiments|preformed the experiments|analyzed the results|wrote the manuscript which was reviewed and approved by all authors	designed the experiments	Conceived and designed the experiments	Methodology	YES
5673865	29110104	ZC	2	designed the experiments|preformed the experiments|analyzed the results|wrote the manuscript which was reviewed and approved by all authors	preformed the experiments	Performed the experiments	Investigation	YES
5673865	29110104	ZC	2	designed the experiments|preformed the experiments|analyzed the results|wrote the manuscript which was reviewed and approved by all authors	analyzed the results	Analyzed the data	Formal analysis	YES
5673865	29110104	ZC	2	designed the experiments|preformed the experiments|analyzed the results|wrote the manuscript which was reviewed and approved by all authors	wrote the manuscript which was reviewed and approved by all authors	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5673865	29110104	ZPL	2	preformed the experiments	preformed the experiments	Performed the experiments	Investigation	YES
4416818	25932948	DB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416818	25932948	DB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416818	25932948	DB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416818	25932948	DB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416818	25932948	JK	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416818	25932948	JK	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416818	25932948	JK	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416818	25932948	KL	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416818	25932948	KL	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416818	25932948	TH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416818	25932948	TH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416818	25932948	VRH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416818	25932948	VRH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5808121	29467779	DZ	2	designed the research|performed the experiments and analyzed data	designed the research	Conceived and designed the experiments	Methodology	YES
5808121	29467779	DZ	2	designed the research|performed the experiments and analyzed data	performed the experiments and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5808121	29467779	GA	2	organized the entire of this research|designed the research|wrote the manuscript	organized the entire of this research	-	-	NO
5808121	29467779	GA	2	organized the entire of this research|designed the research|wrote the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
5808121	29467779	GA	2	organized the entire of this research|designed the research|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5808121	29467779	HY	2	designed the research|performed the experiments and analyzed data|wrote the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
5808121	29467779	HY	2	designed the research|performed the experiments and analyzed data|wrote the manuscript	performed the experiments and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5808121	29467779	HY	2	designed the research|performed the experiments and analyzed data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5808121	29467779	JY	2	designed the research|performed the experiments and analyzed data	designed the research	Conceived and designed the experiments	Methodology	YES
5808121	29467779	JY	2	designed the research|performed the experiments and analyzed data	performed the experiments and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5808121	29467779	WL	2	designed the research|performed the experiments and analyzed data	designed the research	Conceived and designed the experiments	Methodology	YES
5808121	29467779	WL	2	designed the research|performed the experiments and analyzed data	performed the experiments and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5753469	29298685	AK	2	designed the study, performed experiments and wrote the manuscript|designed the analytical strategy|interpreted data	designed the study, performed experiments and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5753469	29298685	AK	2	designed the study, performed experiments and wrote the manuscript|designed the analytical strategy|interpreted data	designed the analytical strategy	Conceived and designed the experiments	-	YES
5753469	29298685	AK	2	designed the study, performed experiments and wrote the manuscript|designed the analytical strategy|interpreted data	interpreted data	Analyzed the data	Formal analysis	YES
5753469	29298685	All authors	2	improved the manuscript and approved the final manuscript	improved the manuscript and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5753469	29298685	KN	2	designed the analytical strategy|interpreted data|completed the manuscript	designed the analytical strategy	Conceived and designed the experiments	-	YES
5753469	29298685	KN	2	designed the analytical strategy|interpreted data|completed the manuscript	interpreted data	Analyzed the data	Formal analysis	YES
5753469	29298685	KN	2	designed the analytical strategy|interpreted data|completed the manuscript	completed the manuscript	-	-	NO
5753469	29298685	ST	2	interpreted data|completed the manuscript|supervised the work	interpreted data	Analyzed the data	Formal analysis	YES
5753469	29298685	ST	2	interpreted data|completed the manuscript|supervised the work	completed the manuscript	-	-	NO
5753469	29298685	ST	2	interpreted data|completed the manuscript|supervised the work	supervised the work	-	Supervision	YES
4637027	26583085	Fang Zhang	2	contribute equally to this work	contribute equally to this work	-	-	NO
4637027	26583085	Xiao-Mei Zhong	2	contribute equally to this work	contribute equally to this work	-	-	NO
4920337	27325833	F.R.	2	ran the analyses and drafted a first version of the manuscript	ran the analyses and drafted a first version of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4920337	27325833	The authors	2	jointly designed the study	jointly designed the study	Conceived and designed the experiments	Methodology	YES
3886219	24453913	Alireza Zandifar	2	had substantial contributions to conception and design of the study, analysis of the data, and drafting of the paper	had substantial contributions to conception and design of the study, analysis of the data, and drafting of the paper	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Methodology|Resources|Writing - Original Draft	YES
3886219	24453913	Faraidoon Haghdoost	2	had contributions to data collection and data analysis|also contributed in the drafting of the paper	had contributions to data collection and data analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
3886219	24453913	Faraidoon Haghdoost	2	had contributions to data collection and data analysis|also contributed in the drafting of the paper	also contributed in the drafting of the paper	Wrote the paper	Writing - Original Draft	YES
3886219	24453913	Maryam Taheriun	2	had contributions to data collection and data analysis|also contributed in the drafting of the paper	had contributions to data collection and data analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
3886219	24453913	Maryam Taheriun	2	had contributions to data collection and data analysis|also contributed in the drafting of the paper	also contributed in the drafting of the paper	Wrote the paper	Writing - Original Draft	YES
3886219	24453913	Mohamadhasan Tajaddini	2	had contributions to data collection and data analysis|also contributed in the drafting of the paper	had contributions to data collection and data analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
3886219	24453913	Mohamadhasan Tajaddini	2	had contributions to data collection and data analysis|also contributed in the drafting of the paper	also contributed in the drafting of the paper	Wrote the paper	Writing - Original Draft	YES
3886219	24453913	Samira Soleimani	2	had contributions to data collection and data analysis|also contributed in the drafting of the paper	had contributions to data collection and data analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
3886219	24453913	Samira Soleimani	2	had contributions to data collection and data analysis|also contributed in the drafting of the paper	also contributed in the drafting of the paper	Wrote the paper	Writing - Original Draft	YES
3886219	24453913	Shaghayegh Haghjooy Javanmard	2	had substantial contributions to conception and design of the study, analysis of the data, and drafting of the paper	had substantial contributions to conception and design of the study, analysis of the data, and drafting of the paper	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Methodology|Resources|Writing - Original Draft	YES
1975466	17878952	DG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1975466	17878952	DG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1975466	17878952	DG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1975466	17878952	MH	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1975466	17878952	MH	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1975466	17878952	RB	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1975466	17878952	RB	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1975466	17878952	SG	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1975466	17878952	SG	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1975466	17878952	WD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1975466	17878952	WD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1975466	17878952	WD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1975466	17878952	ZW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1975466	17878952	ZW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1975466	17878952	ZW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1975466	17878952	ZW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1975466	17878952	ZX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1975466	17878952	ZX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1975466	17878952	ZX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1975466	17878952	ZX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1975466	17878952	ZX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416819	25933003	CHL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4416819	25933003	CHL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416819	25933003	CHT	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416819	25933003	CJL	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416819	25933003	DJY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416819	25933003	DJY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416819	25933003	DJY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416819	25933003	DJY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416819	25933003	DJY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416819	25933003	HHS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416819	25933003	HYH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416819	25933003	HYH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416819	25933003	HYH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416819	25933003	HYH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416819	25933003	HYH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416819	25933003	SKF	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416819	25933003	WSH	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
6166128	30104407	LP	2	noticed the similarity between the amino terminus of pol1 and the histone-binding motif of mcm2	noticed the similarity between the amino terminus of pol1 and the histone-binding motif of mcm2	-	-	NO
4637028	26583109	Astrid Lehner	2	conducted the study, including patient recruitment and data collection	conducted the study, including patient recruitment and data collection	Performed the experiments	Investigation	YES
4637028	26583109	Berthold Langguth	2	designed the study|conducted the study, including patient recruitment and data collection	designed the study	Conceived and designed the experiments	Methodology	YES
4637028	26583109	Berthold Langguth	2	designed the study|conducted the study, including patient recruitment and data collection	conducted the study, including patient recruitment and data collection	Performed the experiments	Investigation	YES
4637028	26583109	Elmar Frank	2	conducted the study, including patient recruitment and data collection	conducted the study, including patient recruitment and data collection	Performed the experiments	Investigation	YES
4637028	26583109	Martin Schecklmann	2	conducted the study, including patient recruitment and data collection|were responsible for the data analysis	conducted the study, including patient recruitment and data collection	Performed the experiments	Investigation	YES
4637028	26583109	Martin Schecklmann	2	conducted the study, including patient recruitment and data collection|were responsible for the data analysis	were responsible for the data analysis	Analyzed the data	Formal analysis	YES
4637028	26583109	Maximilian Pregler	2	were responsible for the data analysis	were responsible for the data analysis	Analyzed the data	Formal analysis	YES
4637028	26583109	Michael Landgrebe	2	designed the study|conducted the study, including patient recruitment and data collection	designed the study	Conceived and designed the experiments	Methodology	YES
4637028	26583109	Michael Landgrebe	2	designed the study|conducted the study, including patient recruitment and data collection	conducted the study, including patient recruitment and data collection	Performed the experiments	Investigation	YES
4637028	26583109	Peter M. Kreuzer	2	conducted the study, including patient recruitment and data collection	conducted the study, including patient recruitment and data collection	Performed the experiments	Investigation	YES
4637028	26583109	Tatjana Cronlein	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
4637028	26583109	Timm B. Poeppl	2	conducted the study, including patient recruitment and data collection	conducted the study, including patient recruitment and data collection	Performed the experiments	Investigation	YES
5753478	29298683	A.V.	PLoS52	performed computational analysis of the data	performed computational analysis of the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5753478	29298683	A.V.D.L.	PLoS52	wrote the paper|conceived the project|analyzed the data	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5753478	29298683	A.V.D.L.	PLoS52	wrote the paper|conceived the project|analyzed the data	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5753478	29298683	A.V.D.L.	PLoS52	wrote the paper|conceived the project|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5753478	29298683	D.A.C.	PLoS52	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5753478	29298683	H.N.G.	PLoS52	conceived the project|performed experiments	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5753478	29298683	H.N.G.	PLoS52	conceived the project|performed experiments	performed experiments	Performed the experiments	Investigation	YES
5753478	29298683	M.C.L.	PLoS52	wrote the paper|conceived the project|performed computational analysis of the data|analyzed the data	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5753478	29298683	M.C.L.	PLoS52	wrote the paper|conceived the project|performed computational analysis of the data|analyzed the data	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5753478	29298683	M.C.L.	PLoS52	wrote the paper|conceived the project|performed computational analysis of the data|analyzed the data	performed computational analysis of the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5753478	29298683	M.C.L.	PLoS52	wrote the paper|conceived the project|performed computational analysis of the data|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5753478	29298683	M.G.	PLoS52	wrote the paper|conceived the project|performed experiments|analyzed the data	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5753478	29298683	M.G.	PLoS52	wrote the paper|conceived the project|performed experiments|analyzed the data	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5753478	29298683	M.G.	PLoS52	wrote the paper|conceived the project|performed experiments|analyzed the data	performed experiments	Performed the experiments	Investigation	YES
5753478	29298683	M.G.	PLoS52	wrote the paper|conceived the project|performed experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5753478	29298683	P.M.	PLoS52	wrote the paper|conceived the project|analyzed the data	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5753478	29298683	P.M.	PLoS52	wrote the paper|conceived the project|analyzed the data	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5753478	29298683	P.M.	PLoS52	wrote the paper|conceived the project|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5676586	29116481	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5676586	29116481	BXZ	PLoS52	revised the paper	revised the paper	Wrote the paper	Writing - Review & Editing	YES
5676586	29116481	HL	PLoS52	revised the paper	revised the paper	Wrote the paper	Writing - Review & Editing	YES
5676586	29116481	KJL	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5676586	29116481	PBD	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5676586	29116481	QFB	PLoS52	performed the experiments|analyzed the data|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5676586	29116481	QFB	PLoS52	performed the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5676586	29116481	QFB	PLoS52	performed the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5676586	29116481	QHC	PLoS52	designed the experiments|performed the experiments|analyzed the data	designed the experiments	Conceived and designed the experiments	Methodology	YES
5676586	29116481	QHC	PLoS52	designed the experiments|performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5676586	29116481	QHC	PLoS52	designed the experiments|performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5676586	29116481	The authors	PLoS52	declare that they have no completing interests	declare that they have no completing interests	-	-	NO
5676586	29116481	WWZ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5676586	29116481	XRY	PLoS52	revised the paper	revised the paper	Wrote the paper	Writing - Review & Editing	YES
5676586	29116481	XYL	PLoS52	designed the experiments|revised the paper	designed the experiments	Conceived and designed the experiments	Methodology	YES
5676586	29116481	XYL	PLoS52	designed the experiments|revised the paper	revised the paper	Wrote the paper	Writing - Review & Editing	YES
5808122	29467780	JW	2	guided the intention and outline of the review|critically revised and re-wrote parts of the manuscript	guided the intention and outline of the review	-	Supervision	YES
5808122	29467780	JW	2	guided the intention and outline of the review|critically revised and re-wrote parts of the manuscript	critically revised and re-wrote parts of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5808122	29467780	LX	2	critically revised and re-wrote parts of the manuscript	critically revised and re-wrote parts of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5808122	29467780	QY	2	prepared the manuscript draft	prepared the manuscript draft	Wrote the paper	Writing - Original Draft	YES
5808122	29467780	XY	2	critically revised and re-wrote parts of the manuscript	critically revised and re-wrote parts of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5808122	29467780	ZP	2	critically revised and re-wrote parts of the manuscript	critically revised and re-wrote parts of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4416820	25932921	BY	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416820	25932921	FY	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416820	25932921	RB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416820	25932921	RS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416820	25932921	RS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416820	25932921	RS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416820	25932921	WY	PLoS5	Conceived and designed the experiments|Performed the experiments|Revised the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416820	25932921	WY	PLoS5	Conceived and designed the experiments|Performed the experiments|Revised the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4416820	25932921	WY	PLoS5	Conceived and designed the experiments|Performed the experiments|Revised the manuscript	Revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
6270720	25211006	Chin Ping Tan	2	revised and approved the final version of the manuscript	revised and approved the final version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
6270720	25211006	Hoda Jafarizadeh Malmiri	2	contributed helpful discussion during the preparation of manuscript	contributed helpful discussion during the preparation of manuscript	Wrote the paper	Writing - Original Draft	YES
6270720	25211006	Ibrahim Al-Resayes	2	contributed with valuable discussions and scientific advice	contributed with valuable discussions and scientific advice	-	-	NO
6270720	25211006	Navideh Anarjan	2	carried out the experiment, conducted the experimental design and prepared the manuscript	carried out the experiment, conducted the experimental design and prepared the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
1975467	17878941	FL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1975467	17878941	FL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1975467	17878941	FL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1975467	17878941	FL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1975467	17878941	JF	PLoS5	Conceived and designed the experiments|Collected the materials	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1975467	17878941	JF	PLoS5	Conceived and designed the experiments|Collected the materials	Collected the materials	Performed the experiments	Investigation	YES
1975467	17878941	JP	PLoS5	Collected the materials	Collected the materials	Performed the experiments	Investigation	YES
1975467	17878941	MF	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1975467	17878941	ML	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1975467	17878941	ML	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1975467	17878941	SH	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1975467	17878941	SH	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1975467	17878941	TO	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1975467	17878941	TO	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
6166131	30150325	All authors	2	commented on the manuscript	commented on the manuscript	-	-	NO
6166131	30150325	BW	2	performed plasmid construction	performed plasmid construction	Performed the experiments	Investigation	YES
6166131	30150325	HD	2	prepared plant materials	prepared plant materials	Performed the experiments	Investigation	YES
6166131	30150325	JX	2	provided useful critiques of the manuscript	provided useful critiques of the manuscript	-	-	NO
6166131	30150325	KC	2	designed experiments|wrote the manuscript	designed experiments	Conceived and designed the experiments	Methodology	YES
6166131	30150325	KC	2	designed experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6166131	30150325	LX	2	designed experiments and performed immunoblotting, phenotyping, and data analysis|wrote the manuscript	designed experiments and performed immunoblotting, phenotyping, and data analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
6166131	30150325	LX	2	designed experiments and performed immunoblotting, phenotyping, and data analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6166131	30150325	SX	2	performed qrt pcr and transgenic analyses	performed qrt pcr and transgenic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6166131	30150325	YL	2	performed chip, immunoblotting, qrt pcr, and plant material preparation	performed chip, immunoblotting, qrt pcr, and plant material preparation	Performed the experiments	Investigation	YES
6166131	30150325	YX	2	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
6166131	30150325	ZL	2	analyzed mass-spectrum data	analyzed mass-spectrum data	Analyzed the data	Formal analysis	YES
5681455	29127658	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5681455	29127658	MM	2	helped design the experiments	helped design the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5681455	29127658	MZ	2	helped design the experiments|conceived the study	helped design the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5681455	29127658	MZ	2	helped design the experiments|conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5681455	29127658	SA	2	designed and performed the experiments and helped draft the manuscript|conceived the study	designed and performed the experiments and helped draft the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5681455	29127658	SA	2	designed and performed the experiments and helped draft the manuscript|conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5681455	29127658	ZJS	2	designed and performed the experiments and helped draft the manuscript	designed and performed the experiments and helped draft the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5808166	29467789	BJ	2	conceived the study|conducted the study and analyzed the results|wrote and reviewed the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5808166	29467789	BJ	2	conceived the study|conducted the study and analyzed the results|wrote and reviewed the manuscript	conducted the study and analyzed the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5808166	29467789	BJ	2	conceived the study|conducted the study and analyzed the results|wrote and reviewed the manuscript	wrote and reviewed the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5808166	29467789	LC-U	2	wrote and reviewed the manuscript	wrote and reviewed the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5808166	29467789	RU	2	conceived the study|wrote and reviewed the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5808166	29467789	RU	2	conceived the study|wrote and reviewed the manuscript	wrote and reviewed the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5753479	29298680	DG	2	provided and customized the gui of the goblet standalone software|significantly contributed to the manuscript|read and approved the manuscript and contributed to its revision	provided and customized the gui of the goblet standalone software	Contributed reagents/materials/analysis tools	Software	YES
5753479	29298680	DG	2	provided and customized the gui of the goblet standalone software|significantly contributed to the manuscript|read and approved the manuscript and contributed to its revision	significantly contributed to the manuscript	-	-	NO
5753479	29298680	DG	2	provided and customized the gui of the goblet standalone software|significantly contributed to the manuscript|read and approved the manuscript and contributed to its revision	read and approved the manuscript and contributed to its revision	Wrote the paper	Writing - Review & Editing	YES
5753479	29298680	IMS	2	designed the study|performed the research and analyzed the data|jointly interpreted the data|drafted the manuscript|read and approved the manuscript and contributed to its revision	designed the study	Conceived and designed the experiments	Methodology	YES
5753479	29298680	IMS	2	designed the study|performed the research and analyzed the data|jointly interpreted the data|drafted the manuscript|read and approved the manuscript and contributed to its revision	performed the research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5753479	29298680	IMS	2	designed the study|performed the research and analyzed the data|jointly interpreted the data|drafted the manuscript|read and approved the manuscript and contributed to its revision	jointly interpreted the data	Analyzed the data	Formal analysis	YES
5753479	29298680	IMS	2	designed the study|performed the research and analyzed the data|jointly interpreted the data|drafted the manuscript|read and approved the manuscript and contributed to its revision	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5753479	29298680	IMS	2	designed the study|performed the research and analyzed the data|jointly interpreted the data|drafted the manuscript|read and approved the manuscript and contributed to its revision	read and approved the manuscript and contributed to its revision	Wrote the paper	Writing - Review & Editing	YES
5753479	29298680	IS	2	conceived and supervised the work|designed the study|jointly interpreted the data|significantly contributed to the manuscript|read and approved the manuscript and contributed to its revision	conceived and supervised the work	Conceived and designed the experiments	Conceptualization|Supervision	YES
5753479	29298680	IS	2	conceived and supervised the work|designed the study|jointly interpreted the data|significantly contributed to the manuscript|read and approved the manuscript and contributed to its revision	designed the study	Conceived and designed the experiments	Methodology	YES
5753479	29298680	IS	2	conceived and supervised the work|designed the study|jointly interpreted the data|significantly contributed to the manuscript|read and approved the manuscript and contributed to its revision	jointly interpreted the data	Analyzed the data	Formal analysis	YES
5753479	29298680	IS	2	conceived and supervised the work|designed the study|jointly interpreted the data|significantly contributed to the manuscript|read and approved the manuscript and contributed to its revision	significantly contributed to the manuscript	-	-	NO
5753479	29298680	IS	2	conceived and supervised the work|designed the study|jointly interpreted the data|significantly contributed to the manuscript|read and approved the manuscript and contributed to its revision	read and approved the manuscript and contributed to its revision	Wrote the paper	Writing - Review & Editing	YES
5753479	29298680	RT	2	conceived and supervised the work|designed the study|jointly interpreted the data|significantly contributed to the manuscript|read and approved the manuscript and contributed to its revision	conceived and supervised the work	Conceived and designed the experiments	Conceptualization|Supervision	YES
5753479	29298680	RT	2	conceived and supervised the work|designed the study|jointly interpreted the data|significantly contributed to the manuscript|read and approved the manuscript and contributed to its revision	designed the study	Conceived and designed the experiments	Methodology	YES
5753479	29298680	RT	2	conceived and supervised the work|designed the study|jointly interpreted the data|significantly contributed to the manuscript|read and approved the manuscript and contributed to its revision	jointly interpreted the data	Analyzed the data	Formal analysis	YES
5753479	29298680	RT	2	conceived and supervised the work|designed the study|jointly interpreted the data|significantly contributed to the manuscript|read and approved the manuscript and contributed to its revision	significantly contributed to the manuscript	-	-	NO
5753479	29298680	RT	2	conceived and supervised the work|designed the study|jointly interpreted the data|significantly contributed to the manuscript|read and approved the manuscript and contributed to its revision	read and approved the manuscript and contributed to its revision	Wrote the paper	Writing - Review & Editing	YES
4416821	25932922	ASM	PLoS5	Performed the experiments|Analyzed the data|Participated in the presentation of the manuscript|Reviewed and approved the final content of the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4416821	25932922	ASM	PLoS5	Performed the experiments|Analyzed the data|Participated in the presentation of the manuscript|Reviewed and approved the final content of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4416821	25932922	ASM	PLoS5	Performed the experiments|Analyzed the data|Participated in the presentation of the manuscript|Reviewed and approved the final content of the manuscript	Participated in the presentation of the manuscript	-	-	NO
4416821	25932922	ASM	PLoS5	Performed the experiments|Analyzed the data|Participated in the presentation of the manuscript|Reviewed and approved the final content of the manuscript	Reviewed and approved the final content of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4416821	25932922	HLJ	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Reviewed and approved the final content of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4416821	25932922	HLJ	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Reviewed and approved the final content of the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416821	25932922	HLJ	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Reviewed and approved the final content of the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416821	25932922	HLJ	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Reviewed and approved the final content of the manuscript	Reviewed and approved the final content of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4416821	25932922	HS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Reviewed and approved the final content of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4416821	25932922	HS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Reviewed and approved the final content of the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416821	25932922	HS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Reviewed and approved the final content of the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416821	25932922	HS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Reviewed and approved the final content of the manuscript	Reviewed and approved the final content of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4416821	25932922	JF	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Reviewed and approved the final content of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4416821	25932922	JF	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Reviewed and approved the final content of the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416821	25932922	JF	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Reviewed and approved the final content of the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416821	25932922	JF	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Reviewed and approved the final content of the manuscript	Reviewed and approved the final content of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4416821	25932922	KKM	PLoS5	Performed the experiments|Analyzed the data|Participated in the presentation of the manuscript|Reviewed and approved the final content of the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4416821	25932922	KKM	PLoS5	Performed the experiments|Analyzed the data|Participated in the presentation of the manuscript|Reviewed and approved the final content of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4416821	25932922	KKM	PLoS5	Performed the experiments|Analyzed the data|Participated in the presentation of the manuscript|Reviewed and approved the final content of the manuscript	Participated in the presentation of the manuscript	-	-	NO
4416821	25932922	KKM	PLoS5	Performed the experiments|Analyzed the data|Participated in the presentation of the manuscript|Reviewed and approved the final content of the manuscript	Reviewed and approved the final content of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4416821	25932922	RS	PLoS5	Performed the experiments|Analyzed the data|Participated in the presentation of the manuscript|Reviewed and approved the final content of the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4416821	25932922	RS	PLoS5	Performed the experiments|Analyzed the data|Participated in the presentation of the manuscript|Reviewed and approved the final content of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4416821	25932922	RS	PLoS5	Performed the experiments|Analyzed the data|Participated in the presentation of the manuscript|Reviewed and approved the final content of the manuscript	Participated in the presentation of the manuscript	-	-	NO
4416821	25932922	RS	PLoS5	Performed the experiments|Analyzed the data|Participated in the presentation of the manuscript|Reviewed and approved the final content of the manuscript	Reviewed and approved the final content of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4416821	25932922	SI	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Reviewed and approved the final content of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4416821	25932922	SI	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Reviewed and approved the final content of the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416821	25932922	SI	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Reviewed and approved the final content of the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416821	25932922	SI	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Reviewed and approved the final content of the manuscript	Reviewed and approved the final content of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4416821	25932922	SKS	PLoS5	Performed the experiments|Analyzed the data|Participated in the presentation of the manuscript|Reviewed and approved the final content of the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4416821	25932922	SKS	PLoS5	Performed the experiments|Analyzed the data|Participated in the presentation of the manuscript|Reviewed and approved the final content of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4416821	25932922	SKS	PLoS5	Performed the experiments|Analyzed the data|Participated in the presentation of the manuscript|Reviewed and approved the final content of the manuscript	Participated in the presentation of the manuscript	-	-	NO
4416821	25932922	SKS	PLoS5	Performed the experiments|Analyzed the data|Participated in the presentation of the manuscript|Reviewed and approved the final content of the manuscript	Reviewed and approved the final content of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4416821	25932922	SS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Reviewed and approved the final content of the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416821	25932922	SS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Reviewed and approved the final content of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4416821	25932922	SS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Reviewed and approved the final content of the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416821	25932922	SS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Reviewed and approved the final content of the manuscript	Reviewed and approved the final content of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4416821	25932922	YPB	PLoS5	Performed the experiments|Analyzed the data|Participated in the presentation of the manuscript|Reviewed and approved the final content of the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4416821	25932922	YPB	PLoS5	Performed the experiments|Analyzed the data|Participated in the presentation of the manuscript|Reviewed and approved the final content of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4416821	25932922	YPB	PLoS5	Performed the experiments|Analyzed the data|Participated in the presentation of the manuscript|Reviewed and approved the final content of the manuscript	Participated in the presentation of the manuscript	-	-	NO
4416821	25932922	YPB	PLoS5	Performed the experiments|Analyzed the data|Participated in the presentation of the manuscript|Reviewed and approved the final content of the manuscript	Reviewed and approved the final content of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4920342	27325838	All authors	2	made substantial contributions to conception and design, or acquisition of data, or analysis and interpretation of data and drafting the article or revising it critically for important intellectual content	made substantial contributions to conception and design, or acquisition of data, or analysis and interpretation of data and drafting the article or revising it critically for important intellectual content	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
6270721	25207712	A. Alianca	2	contributed in design, analysis of the results and writing the paper	contributed in design, analysis of the results and writing the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6270721	25207712	All authors	2	contributed to this paper	contributed to this paper	-	-	NO
6270721	25207712	C. Castro	2	performed flow cytometric assay	performed flow cytometric assay	Performed the experiments	Investigation	YES
6270721	25207712	M. Bianco	2	was responsible by seaweed collection, extract preparation and chemical support	was responsible by seaweed collection, extract preparation and chemical support	-	-	NO
6270721	25207712	R.C.B.Q.	2	contributed in design, analysis of the results and writing the paper	contributed in design, analysis of the results and writing the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6270721	25207712	T.N.V.	2	was responsible by seaweed collection and botanical identification	was responsible by seaweed collection and botanical identification	Performed the experiments	Investigation	YES
1975468	17878931	CA	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1975468	17878931	EC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1975468	17878931	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1975468	17878931	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1975468	17878931	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1975468	17878931	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1975468	17878931	JB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1975468	17878931	MJ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1975468	17878931	RF	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1975468	17878931	RF	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416822	25933036	ASJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416822	25933036	ASJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416822	25933036	ASJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416822	25933036	ASJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416822	25933036	BKL	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416822	25933036	BKL	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416822	25933036	HP	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416822	25933036	HP	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416822	25933036	HP	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416822	25933036	JJ	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416822	25933036	JJ	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416822	25933036	JS	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416822	25933036	JS	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416822	25933036	RH	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416822	25933036	RH	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416822	25933036	SN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416822	25933036	SN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416822	25933036	SN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416822	25933036	SN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6166134	30177573	AJB	2	conceived of the study|jointly carried out the experiments, analysed the data and wrote the manuscript	conceived of the study	Conceived and designed the experiments	Conceptualization	YES
6166134	30177573	AJB	2	conceived of the study|jointly carried out the experiments, analysed the data and wrote the manuscript	jointly carried out the experiments, analysed the data and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6166134	30177573	JRH-F	2	contributed to sample preparation and analysis of mass spectrometry experiments	contributed to sample preparation and analysis of mass spectrometry experiments	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
6166134	30177573	MJA-S	2	jointly carried out the experiments, analysed the data and wrote the manuscript	jointly carried out the experiments, analysed the data and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5753484	29298677	AC	2	have contributed equally to this research work and manuscript	have contributed equally to this research work and manuscript	Performed the experiments	Investigation	YES
5753484	29298677	GG	2	have contributed equally to this research work and manuscript	have contributed equally to this research work and manuscript	Performed the experiments	Investigation	YES
5681456	29127501	All authors	2	contributed during experimental work and scientific writing of this manuscript|read and approved the final manuscript	contributed during experimental work and scientific writing of this manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5681456	29127501	All authors	2	contributed during experimental work and scientific writing of this manuscript|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5681456	29127501	JC	2	isolated the new novel strain for the very first time	isolated the new novel strain for the very first time	Performed the experiments	Investigation	YES
5681456	29127501	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5681456	29127501	YK	2	isolated the new novel strain for the very first time	isolated the new novel strain for the very first time	Performed the experiments	Investigation	YES
5808167	29467771	FW	2	performed phenotyping	performed phenotyping	Performed the experiments	Investigation	YES
5808167	29467771	HW	2	performed experiments and drafted the manuscript	performed experiments and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5808167	29467771	JB	2	did genetic transformation	did genetic transformation	Performed the experiments	Investigation	YES
5808167	29467771	WR	2	performed experiments and drafted the manuscript	performed experiments and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5808167	29467771	YH	2	designed the research plan and wrote the manuscript	designed the research plan and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4416823	25933347	CL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416823	25933347	CL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416823	25933347	CL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416823	25933347	DZ	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416823	25933347	XD	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416823	25933347	XZ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416823	25933347	YY	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416823	25933347	YY	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416823	25933347	YY	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416823	25933347	ZL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416823	25933347	ZL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416823	25933347	ZL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4938023	27377732	J.V.G.	2	designed the research|performed the research|analysed data|wrote the study	designed the research	Conceived and designed the experiments	Methodology	YES
4938023	27377732	J.V.G.	2	designed the research|performed the research|analysed data|wrote the study	performed the research	Performed the experiments	Investigation	YES
4938023	27377732	J.V.G.	2	designed the research|performed the research|analysed data|wrote the study	analysed data	Analyzed the data	Formal analysis	YES
4938023	27377732	J.V.G.	2	designed the research|performed the research|analysed data|wrote the study	wrote the study	Wrote the paper	Writing - Original Draft	YES
4938023	27377732	O.G.	2	designed the research|performed the research|analysed data	designed the research	Conceived and designed the experiments	Methodology	YES
4938023	27377732	O.G.	2	designed the research|performed the research|analysed data	performed the research	Performed the experiments	Investigation	YES
4938023	27377732	O.G.	2	designed the research|performed the research|analysed data	analysed data	Analyzed the data	Formal analysis	YES
4938023	27377732	O.H.P.	2	designed the research|wrote the study	designed the research	Conceived and designed the experiments	Methodology	YES
4938023	27377732	O.H.P.	2	designed the research|wrote the study	wrote the study	Wrote the paper	Writing - Original Draft	YES
4938023	27377732	O.V.G.	2	designed the research|analysed data|wrote the study	designed the research	Conceived and designed the experiments	Methodology	YES
4938023	27377732	O.V.G.	2	designed the research|analysed data|wrote the study	analysed data	Analyzed the data	Formal analysis	YES
4938023	27377732	O.V.G.	2	designed the research|analysed data|wrote the study	wrote the study	Wrote the paper	Writing - Original Draft	YES
4938023	27377732	S.P.	2	designed the research|performed the research|analysed data	designed the research	Conceived and designed the experiments	Methodology	YES
4938023	27377732	S.P.	2	designed the research|performed the research|analysed data	performed the research	Performed the experiments	Investigation	YES
4938023	27377732	S.P.	2	designed the research|performed the research|analysed data	analysed data	Analyzed the data	Formal analysis	YES
4938023	27377732	S.S.	2	designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
4938023	27377732	T.T.	2	designed the research|performed the research|analysed data	designed the research	Conceived and designed the experiments	Methodology	YES
4938023	27377732	T.T.	2	designed the research|performed the research|analysed data	performed the research	Performed the experiments	Investigation	YES
4938023	27377732	T.T.	2	designed the research|performed the research|analysed data	analysed data	Analyzed the data	Formal analysis	YES
1975469	17878942	CB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1975469	17878942	CB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1975469	17878942	CV	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1975469	17878942	CV	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1975469	17878942	DC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1975469	17878942	DC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1975469	17878942	DC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1975469	17878942	DC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1975469	17878942	DR	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1975469	17878942	DR	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1975469	17878942	DR	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1975469	17878942	DS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1975469	17878942	DS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1975469	17878942	DS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1975469	17878942	JJ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1975469	17878942	JM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1975469	17878942	JM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1975469	17878942	JM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1975469	17878942	JN	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1975469	17878942	MM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1975469	17878942	MM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1975469	17878942	MM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1975469	17878942	MM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1975469	17878942	MM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1975469	17878942	PZ	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1975469	17878942	PZ	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1975469	17878942	RF	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1975469	17878942	RF	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5686038	29138995	VB	1	Planning and designing of study	Planning and designing of study	Conceived and designed the experiments	Methodology	YES
5808188	29467777	DT	2	conceived and designed the study, collected the in situ data, performed data analysis and interpretation, and drafted the article	conceived and designed the study, collected the in situ data, performed data analysis and interpretation, and drafted the article	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5808188	29467777	PR	2	supervised the whole study, from the conception to the drafting and critical revision	supervised the whole study, from the conception to the drafting and critical revision	Conceived and designed the experiments|Wrote the paper	Conceptualization|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
4416824	25933038	CS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416824	25933038	CS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416824	25933038	CS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416824	25933038	ESG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416824	25933038	HS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416824	25933038	HS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416824	25933038	ME	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416824	25933038	ME	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416824	25933038	MVP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416824	25933038	TVA	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416824	25933038	TVA	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416824	25933038	TVA	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5753508	29298673	AS	2	prepared the dna and rna samples	prepared the dna and rna samples	Performed the experiments	Investigation	YES
5753508	29298673	All authors	2	took part in manuscript writing	took part in manuscript writing	Wrote the paper	Writing - Original Draft	YES
5753508	29298673	CD	2	conceived the work	conceived the work	Conceived and designed the experiments	Conceptualization	YES
5753508	29298673	GT	2	made the mating type analysis	made the mating type analysis	-	-	NO
5753508	29298673	JF	2	performed all bioinformatics including database submissions|conceived the work	performed all bioinformatics including database submissions	Performed the experiments|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Software	YES
5753508	29298673	JF	2	performed all bioinformatics including database submissions|conceived the work	conceived the work	Conceived and designed the experiments	Conceptualization	YES
5753508	29298673	JI	2	prepared the dna and rna samples	prepared the dna and rna samples	Performed the experiments	Investigation	YES
5753508	29298673	SB	2	prepared the dna and rna samples	prepared the dna and rna samples	Performed the experiments	Investigation	YES
1975470	17878928	JM	1	Contributed to the development of the mathematical model|Interpretation of findings|Preparation of the manuscript|Saw and approved the final version of the manuscript	Contributed to the development of the mathematical model	Performed the experiments	Formal analysis|Methodology	YES
1975470	17878928	JM	1	Contributed to the development of the mathematical model|Interpretation of findings|Preparation of the manuscript|Saw and approved the final version of the manuscript	Interpretation of findings	Analyzed the data	Formal analysis	YES
1975470	17878928	JM	1	Contributed to the development of the mathematical model|Interpretation of findings|Preparation of the manuscript|Saw and approved the final version of the manuscript	Preparation of the manuscript	Wrote the paper	Writing - Original Draft	YES
1975470	17878928	JM	1	Contributed to the development of the mathematical model|Interpretation of findings|Preparation of the manuscript|Saw and approved the final version of the manuscript	Saw and approved the final version of the manuscript	-	-	NO
1975470	17878928	RA	1	Contributed to the development of the mathematical model|Interpretation of findings|Preparation of the manuscript|Saw and approved the final version of the manuscript	Contributed to the development of the mathematical model	Performed the experiments	Formal analysis|Methodology	YES
1975470	17878928	RA	1	Contributed to the development of the mathematical model|Interpretation of findings|Preparation of the manuscript|Saw and approved the final version of the manuscript	Interpretation of findings	Analyzed the data	Formal analysis	YES
1975470	17878928	RA	1	Contributed to the development of the mathematical model|Interpretation of findings|Preparation of the manuscript|Saw and approved the final version of the manuscript	Preparation of the manuscript	Wrote the paper	Writing - Original Draft	YES
1975470	17878928	RA	1	Contributed to the development of the mathematical model|Interpretation of findings|Preparation of the manuscript|Saw and approved the final version of the manuscript	Saw and approved the final version of the manuscript	-	-	NO
1975470	17878928	UA	1	Contributed to the development of the mathematical model|Interpretation of findings|Preparation of the manuscript|Collated estimates of model variables|Wrote the manuscript|Saw and approved the final version of the manuscript	Contributed to the development of the mathematical model	Performed the experiments	Formal analysis|Methodology	YES
1975470	17878928	UA	1	Contributed to the development of the mathematical model|Interpretation of findings|Preparation of the manuscript|Collated estimates of model variables|Wrote the manuscript|Saw and approved the final version of the manuscript	Interpretation of findings	Analyzed the data	Formal analysis	YES
1975470	17878928	UA	1	Contributed to the development of the mathematical model|Interpretation of findings|Preparation of the manuscript|Collated estimates of model variables|Wrote the manuscript|Saw and approved the final version of the manuscript	Preparation of the manuscript	Wrote the paper	Writing - Original Draft	YES
1975470	17878928	UA	1	Contributed to the development of the mathematical model|Interpretation of findings|Preparation of the manuscript|Collated estimates of model variables|Wrote the manuscript|Saw and approved the final version of the manuscript	Collated estimates of model variables	Performed the experiments|Analyzed the data	Formal analysis|Methodology	YES
1975470	17878928	UA	1	Contributed to the development of the mathematical model|Interpretation of findings|Preparation of the manuscript|Collated estimates of model variables|Wrote the manuscript|Saw and approved the final version of the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
1975470	17878928	UA	1	Contributed to the development of the mathematical model|Interpretation of findings|Preparation of the manuscript|Collated estimates of model variables|Wrote the manuscript|Saw and approved the final version of the manuscript	Saw and approved the final version of the manuscript	-	-	NO
6187028	30185408	CMP	2	designed the experiments|performed immunostainings, super-resolution and release probability experiments and analyzed the data|designed figures and wrote the manuscript with input from all authors	designed the experiments	Conceived and designed the experiments	Methodology	YES
6187028	30185408	CMP	2	designed the experiments|performed immunostainings, super-resolution and release probability experiments and analyzed the data|designed figures and wrote the manuscript with input from all authors	performed immunostainings, super-resolution and release probability experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6187028	30185408	CMP	2	designed the experiments|performed immunostainings, super-resolution and release probability experiments and analyzed the data|designed figures and wrote the manuscript with input from all authors	designed figures and wrote the manuscript with input from all authors	Conceived and designed the experiments|Wrote the paper	Visualization|Writing - Original Draft	YES
6187028	30185408	DCV	2	fusion experiment	fusion experiment	-	-	NO
6187028	30185408	GABAergic	2	release probability experiment	release probability experiment	-	-	NO
6187028	30185408	JRTW	2	collected and analyzed electron microscopy data	collected and analyzed electron microscopy data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6187028	30185408	MF	2	designed and performed the initial colocalization and release probability experiments	designed and performed the initial colocalization and release probability experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6187028	30185408	MV	2	designed the experiments|designed figures and wrote the manuscript with input from all authors	designed the experiments	Conceived and designed the experiments	Methodology	YES
6187028	30185408	MV	2	designed the experiments|designed figures and wrote the manuscript with input from all authors	designed figures and wrote the manuscript with input from all authors	Conceived and designed the experiments|Wrote the paper	Visualization|Writing - Original Draft	YES
6187028	30185408	RFT	2	designed the experiments|designed figures and wrote the manuscript with input from all authors	designed the experiments	Conceived and designed the experiments	Methodology	YES
6187028	30185408	RFT	2	designed the experiments|designed figures and wrote the manuscript with input from all authors	designed figures and wrote the manuscript with input from all authors	Conceived and designed the experiments|Wrote the paper	Visualization|Writing - Original Draft	YES
4637034	26583115	C. B. Larmonier	2	shared authorship	shared authorship	-	-	NO
4637034	26583115	K. W. Shehab	2	shared authorship	shared authorship	-	-	NO
3167344	21556118	CK	2	participated in the design and coordination of this study	participated in the design and coordination of this study	Conceived and designed the experiments	Methodology|Project administration	YES
3167344	21556118	MH	2	performed the gene expression studies as well as the generation of rrfc1 specific antiserum including immunohistochemical experiments	performed the gene expression studies as well as the generation of rrfc1 specific antiserum including immunohistochemical experiments	Performed the experiments	Investigation	YES
3167344	21556118	SH	2	participated in the immunization of rabbits and prepared the manuscript	participated in the immunization of rabbits and prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
3167344	21556118	WH	2	participated in the design and coordination of this study|additionally advised the preparation of the manuscript	participated in the design and coordination of this study	Conceived and designed the experiments	Methodology|Project administration	YES
3167344	21556118	WH	2	participated in the design and coordination of this study|additionally advised the preparation of the manuscript	additionally advised the preparation of the manuscript	Wrote the paper	Writing - Original Draft	YES
4416825	25933026	IAJB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Likert scale	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416825	25933026	IAJB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Likert scale	Performed the experiments	Performed the experiments	Investigation	YES
4416825	25933026	IAJB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Likert scale	Analyzed the data	Analyzed the data	Formal analysis	YES
4416825	25933026	IAJB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Likert scale	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416825	25933026	IAJB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Likert scale	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416825	25933026	IAJB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Likert scale	Likert scale	-	-	NO
4416825	25933026	MYB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Likert scale	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416825	25933026	MYB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Likert scale	Analyzed the data	Analyzed the data	Formal analysis	YES
4416825	25933026	MYB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Likert scale	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416825	25933026	MYB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Likert scale	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416825	25933026	MYB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Likert scale	Likert scale	-	-	NO
4416825	25933026	SK	PLoS5	Search|Likert scale	Search	-	-	NO
4416825	25933026	SK	PLoS5	Search|Likert scale	Likert scale	-	-	NO
4416825	25933026	SKK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416825	25933026	SKK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416825	25933026	SKK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416825	25933026	SKK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5808204	29467781	FZ	2	provided plants materials	provided plants materials	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5808204	29467781	HR	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5808204	29467781	XZ	2	conceived, designed the experiments|analyzed the data and revised the manuscript|carried out the experiments	conceived, designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5808204	29467781	XZ	2	conceived, designed the experiments|analyzed the data and revised the manuscript|carried out the experiments	analyzed the data and revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5808204	29467781	XZ	2	conceived, designed the experiments|analyzed the data and revised the manuscript|carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5808204	29467781	YX	2	conceived, designed the experiments|analyzed the data and revised the manuscript	conceived, designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5808204	29467781	YX	2	conceived, designed the experiments|analyzed the data and revised the manuscript	analyzed the data and revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5808204	29467781	ZH	2	analyzed the data and revised the manuscript	analyzed the data and revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5808204	29467781	ZS	2	conceived, designed the experiments|analyzed the data and revised the manuscript	conceived, designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5808204	29467781	ZS	2	conceived, designed the experiments|analyzed the data and revised the manuscript	analyzed the data and revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5753575	29298672	AGW	7	provided feedback on the initial draft, involved in data collection, data analysis, statistics, revised the manuscript and made substantial contributions in interpretation of the results	provided feedback on the initial draft, involved in data collection, data analysis, statistics, revised the manuscript and made substantial contributions in interpretation of the results	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5753575	29298672	AJH	7	provided feedback on the initial draft, involved in data collection, data analysis, statistics, revised the manuscript and made substantial contributions in interpretation of the results	provided feedback on the initial draft, involved in data collection, data analysis, statistics, revised the manuscript and made substantial contributions in interpretation of the results	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5753575	29298672	AK	7	provided feedback on the initial draft, involved in data collection, data analysis, statistics, revised the manuscript and made substantial contributions in interpretation of the results	provided feedback on the initial draft, involved in data collection, data analysis, statistics, revised the manuscript and made substantial contributions in interpretation of the results	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5753575	29298672	AM	7	provided feedback on the initial draft, involved in data collection, data analysis, statistics, revised the manuscript and made substantial contributions in interpretation of the results	provided feedback on the initial draft, involved in data collection, data analysis, statistics, revised the manuscript and made substantial contributions in interpretation of the results	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5753575	29298672	AMD	7	provided feedback on the initial draft, involved in data collection, data analysis, statistics, revised the manuscript and made substantial contributions in interpretation of the results	provided feedback on the initial draft, involved in data collection, data analysis, statistics, revised the manuscript and made substantial contributions in interpretation of the results	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5753575	29298672	CK	7	provided feedback on the initial draft, involved in data collection, data analysis, statistics, revised the manuscript and made substantial contributions in interpretation of the results	provided feedback on the initial draft, involved in data collection, data analysis, statistics, revised the manuscript and made substantial contributions in interpretation of the results	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5753575	29298672	CMC	7	provided feedback on the initial draft, involved in data collection, data analysis, statistics, revised the manuscript and made substantial contributions in interpretation of the results	provided feedback on the initial draft, involved in data collection, data analysis, statistics, revised the manuscript and made substantial contributions in interpretation of the results	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5753575	29298672	CP	7	provided feedback on the initial draft, involved in data collection, data analysis, statistics, revised the manuscript and made substantial contributions in interpretation of the results	provided feedback on the initial draft, involved in data collection, data analysis, statistics, revised the manuscript and made substantial contributions in interpretation of the results	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5753575	29298672	FG	7	provided feedback on the initial draft, involved in data collection, data analysis, statistics, revised the manuscript and made substantial contributions in interpretation of the results	provided feedback on the initial draft, involved in data collection, data analysis, statistics, revised the manuscript and made substantial contributions in interpretation of the results	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5753575	29298672	GKS	7	provided feedback on the initial draft, involved in data collection, data analysis, statistics, revised the manuscript and made substantial contributions in interpretation of the results	provided feedback on the initial draft, involved in data collection, data analysis, statistics, revised the manuscript and made substantial contributions in interpretation of the results	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5753575	29298672	IDP	7	conceived the idea, done the initial analysis, wrote the paper and contributed in data collection and interpretation of the results	conceived the idea, done the initial analysis, wrote the paper and contributed in data collection and interpretation of the results	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Resources|Writing - Original Draft	YES
5753575	29298672	IIA	7	provided feedback on the initial draft, involved in data collection, data analysis, statistics, revised the manuscript and made substantial contributions in interpretation of the results	provided feedback on the initial draft, involved in data collection, data analysis, statistics, revised the manuscript and made substantial contributions in interpretation of the results	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5753575	29298672	IVA	7	provided feedback on the initial draft, involved in data collection, data analysis, statistics, revised the manuscript and made substantial contributions in interpretation of the results	provided feedback on the initial draft, involved in data collection, data analysis, statistics, revised the manuscript and made substantial contributions in interpretation of the results	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5753575	29298672	KNN	7	provided feedback on the initial draft, involved in data collection, data analysis, statistics, revised the manuscript and made substantial contributions in interpretation of the results	provided feedback on the initial draft, involved in data collection, data analysis, statistics, revised the manuscript and made substantial contributions in interpretation of the results	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5753575	29298672	MJ	7	provided feedback on the initial draft, involved in data collection, data analysis, statistics, revised the manuscript and made substantial contributions in interpretation of the results	provided feedback on the initial draft, involved in data collection, data analysis, statistics, revised the manuscript and made substantial contributions in interpretation of the results	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5753575	29298672	MM	7	provided feedback on the initial draft, involved in data collection, data analysis, statistics, revised the manuscript and made substantial contributions in interpretation of the results	provided feedback on the initial draft, involved in data collection, data analysis, statistics, revised the manuscript and made substantial contributions in interpretation of the results	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5753575	29298672	MS	7	provided feedback on the initial draft, involved in data collection, data analysis, statistics, revised the manuscript and made substantial contributions in interpretation of the results	provided feedback on the initial draft, involved in data collection, data analysis, statistics, revised the manuscript and made substantial contributions in interpretation of the results	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5753575	29298672	NE	7	provided feedback on the initial draft, involved in data collection, data analysis, statistics, revised the manuscript and made substantial contributions in interpretation of the results	provided feedback on the initial draft, involved in data collection, data analysis, statistics, revised the manuscript and made substantial contributions in interpretation of the results	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5753575	29298672	PC	7	provided feedback on the initial draft, involved in data collection, data analysis, statistics, revised the manuscript and made substantial contributions in interpretation of the results	provided feedback on the initial draft, involved in data collection, data analysis, statistics, revised the manuscript and made substantial contributions in interpretation of the results	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5753575	29298672	PJH	7	provided feedback on the initial draft, involved in data collection, data analysis, statistics, revised the manuscript and made substantial contributions in interpretation of the results	provided feedback on the initial draft, involved in data collection, data analysis, statistics, revised the manuscript and made substantial contributions in interpretation of the results	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5753575	29298672	RE	7	provided feedback on the initial draft, involved in data collection, data analysis, statistics, revised the manuscript and made substantial contributions in interpretation of the results	provided feedback on the initial draft, involved in data collection, data analysis, statistics, revised the manuscript and made substantial contributions in interpretation of the results	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5753575	29298672	SH	7	provided feedback on the initial draft, involved in data collection, data analysis, statistics, revised the manuscript and made substantial contributions in interpretation of the results	provided feedback on the initial draft, involved in data collection, data analysis, statistics, revised the manuscript and made substantial contributions in interpretation of the results	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5753575	29298672	SHD	7	provided feedback on the initial draft, involved in data collection, data analysis, statistics, revised the manuscript and made substantial contributions in interpretation of the results	provided feedback on the initial draft, involved in data collection, data analysis, statistics, revised the manuscript and made substantial contributions in interpretation of the results	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5753575	29298672	SJL	7	provided feedback on the initial draft, involved in data collection, data analysis, statistics, revised the manuscript and made substantial contributions in interpretation of the results	provided feedback on the initial draft, involved in data collection, data analysis, statistics, revised the manuscript and made substantial contributions in interpretation of the results	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5753575	29298672	SV	7	provided feedback on the initial draft, involved in data collection, data analysis, statistics, revised the manuscript and made substantial contributions in interpretation of the results	provided feedback on the initial draft, involved in data collection, data analysis, statistics, revised the manuscript and made substantial contributions in interpretation of the results	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5688048	29143221	Both authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5688048	29143221	DR	2	designed the research|supervised the research|wrote the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
5688048	29143221	DR	2	designed the research|supervised the research|wrote the manuscript	supervised the research	-	Supervision	YES
5688048	29143221	DR	2	designed the research|supervised the research|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5688048	29143221	HW	2	designed the research|wrote the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
5688048	29143221	HW	2	designed the research|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
1975471	17878943	AL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1975471	17878943	AL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1975471	17878943	AL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1975471	17878943	AL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1975471	17878943	EB	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1975471	17878943	EB	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1975471	17878943	LG	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1975471	17878943	LG	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1975471	17878943	LG	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1975471	17878943	MT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1975471	17878943	MT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1975471	17878943	MT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6213277	30237313	All authors	2	contributed to discussion of the research and data interpretation	contributed to discussion of the research and data interpretation	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6213277	30237313	FH	2	performed single-molecule experiments|analyzed the smfret data	performed single-molecule experiments	Performed the experiments	Investigation	YES
6213277	30237313	FH	2	performed single-molecule experiments|analyzed the smfret data	analyzed the smfret data	Analyzed the data	Formal analysis	YES
6213277	30237313	KBe	2	conceived and designed the study, and supervised the project|prepared protein samples and performed functional assays|wrote the manuscript with support from all authors	conceived and designed the study, and supervised the project	Conceived and designed the experiments	Conceptualization|Methodology|Supervision	YES
6213277	30237313	KBe	2	conceived and designed the study, and supervised the project|prepared protein samples and performed functional assays|wrote the manuscript with support from all authors	prepared protein samples and performed functional assays	Performed the experiments	Investigation	YES
6213277	30237313	KBe	2	conceived and designed the study, and supervised the project|prepared protein samples and performed functional assays|wrote the manuscript with support from all authors	wrote the manuscript with support from all authors	Wrote the paper	Writing - Original Draft	YES
6213277	30237313	KBo	2	prepared protein samples and performed functional assays	prepared protein samples and performed functional assays	Performed the experiments	Investigation	YES
6213277	30237313	KT	2	performed single-molecule experiments|analyzed the smfret data	performed single-molecule experiments	Performed the experiments	Investigation	YES
6213277	30237313	KT	2	performed single-molecule experiments|analyzed the smfret data	analyzed the smfret data	Analyzed the data	Formal analysis	YES
6213277	30237313	MB	2	analyzed the smfret data	analyzed the smfret data	Analyzed the data	Formal analysis	YES
6213277	30237313	MR	2	prepared protein samples and performed functional assays	prepared protein samples and performed functional assays	Performed the experiments	Investigation	YES
6213277	30237313	SR	2	prepared the mccj25 peptide	prepared the mccj25 peptide	Performed the experiments	Investigation	YES
6213277	30237313	TC	2	conceived and designed the study, and supervised the project|wrote the manuscript with support from all authors	conceived and designed the study, and supervised the project	Conceived and designed the experiments	Conceptualization|Methodology|Supervision	YES
6213277	30237313	TC	2	conceived and designed the study, and supervised the project|wrote the manuscript with support from all authors	wrote the manuscript with support from all authors	Wrote the paper	Writing - Original Draft	YES
4938026	27377720	All authors	2	contributed to the writing of the manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
4938026	27377720	M.P.	2	produced figures 3 4	produced figures 3 4	-	Visualization	YES
4938026	27377720	P.P.	2	performed the experiments in figures 1 and 2	performed the experiments in figures 1 and 2	Performed the experiments	Investigation|Visualization	YES
3167345	21556124	CK	2	conception and design	conception and design	Conceived and designed the experiments	Conceptualization	YES
3167345	21556124	DY	2	conception, design, data acquisition, article drafting	conception, design, data acquisition, article drafting	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
3167345	21556124	HD	2	data acquisition	data acquisition	Performed the experiments	Investigation	YES
3167345	21556124	JG	2	critical manuscript revision	critical manuscript revision	Wrote the paper	Writing - Review & Editing	YES
3167345	21556124	YR	2	conception, design, data acquisition, article drafting	conception, design, data acquisition, article drafting	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
3167345	21556124	ZS	2	conception, design, data acquisition, analysis and interpretation	conception, design, data acquisition, analysis and interpretation	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation	YES
4416826	25933165	EEW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416826	25933165	FM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4416826	25933165	FM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416826	25933165	IID	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416826	25933165	KOS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416826	25933165	KOS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416826	25933165	KOS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416826	25933165	NS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416826	25933165	RO	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416826	25933165	RR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416826	25933165	RR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416826	25933165	RR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416826	25933165	RR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416826	25933165	SPO	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5808209	29467784	D-DZ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5808209	29467784	DS	PLoS52	edited and re-wrote parts of the manuscript	edited and re-wrote parts of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5808209	29467784	J-JL	PLoS52	prepared biological material	prepared biological material	Performed the experiments	Investigation	YES
5808209	29467784	J-YC	PLoS52	conceived and designed the experiments|wrote the original draft	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5808209	29467784	J-YC	PLoS52	conceived and designed the experiments|wrote the original draft	wrote the original draft	Wrote the paper	Writing - Original Draft	YES
5808209	29467784	KS	PLoS52	conceived and designed the experiments|edited and re-wrote parts of the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5808209	29467784	KS	PLoS52	conceived and designed the experiments|edited and re-wrote parts of the manuscript	edited and re-wrote parts of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5808209	29467784	LZ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5808209	29467784	N-YL	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5808209	29467784	SK	PLoS52	edited and re-wrote parts of the manuscript	edited and re-wrote parts of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5808209	29467784	T-GL	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5808209	29467784	W-QZ	PLoS52	prepared biological material	prepared biological material	Performed the experiments	Investigation	YES
5808209	29467784	X-FD	PLoS52	conceived and designed the experiments|wrote the original draft	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5808209	29467784	X-FD	PLoS52	conceived and designed the experiments|wrote the original draft	wrote the original draft	Wrote the paper	Writing - Original Draft	YES
5808209	29467784	X-FM	PLoS52	prepared biological material	prepared biological material	Performed the experiments	Investigation	YES
5808209	29467784	Y-JG	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5808209	29467784	Z-QK	PLoS52	prepared biological material	prepared biological material	Performed the experiments	Investigation	YES
6270725	24871574	All authors	2	discussed, edited and approved the final version	discussed, edited and approved the final version	Wrote the paper	Writing - Review & Editing	YES
6270725	24871574	E.M.	2	discussed, edited and approved the final version	discussed, edited and approved the final version	Wrote the paper	Writing - Review & Editing	YES
6270725	24871574	G.R.D.N.	2	designed the research|performed the experimental work	designed the research	Conceived and designed the experiments	Methodology	YES
6270725	24871574	G.R.D.N.	2	designed the research|performed the experimental work	performed the experimental work	Performed the experiments	Investigation	YES
6270725	24871574	I.R.	2	designed the research|performed the experimental work|discussed, edited and approved the final version	designed the research	Conceived and designed the experiments	Methodology	YES
6270725	24871574	I.R.	2	designed the research|performed the experimental work|discussed, edited and approved the final version	performed the experimental work	Performed the experiments	Investigation	YES
6270725	24871574	I.R.	2	designed the research|performed the experimental work|discussed, edited and approved the final version	discussed, edited and approved the final version	Wrote the paper	Writing - Review & Editing	YES
6270725	24871574	P.R.	2	designed the research|discussed, edited and approved the final version	designed the research	Conceived and designed the experiments	Methodology	YES
6270725	24871574	P.R.	2	designed the research|discussed, edited and approved the final version	discussed, edited and approved the final version	Wrote the paper	Writing - Review & Editing	YES
5755069	29301494	BLZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5755069	29301494	BLZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
5755069	29301494	BLZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5755069	29301494	DT	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5755069	29301494	SL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5755069	29301494	SLF	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5755069	29301494	YC	PLoS5	Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
5755069	29301494	YC	PLoS5	Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
5755069	29301494	YC	PLoS5	Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5755069	29301494	YC	PLoS5	Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5755069	29301494	YYW	PLoS5	Performed the experiments|Analyzed the data|Wrote the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
5755069	29301494	YYW	PLoS5	Performed the experiments|Analyzed the data|Wrote the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
5755069	29301494	YYW	PLoS5	Performed the experiments|Analyzed the data|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4938030	27377724	A.C.D.	2	conceived the study and wrote the paper, together with the other authors	conceived the study and wrote the paper, together with the other authors	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4938030	27377724	L.F.	2	performed and analysed all calcium imaging experiments	performed and analysed all calcium imaging experiments	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
4938030	27377724	M.N.-R.	2	oversaw the organization of the a 2 d-1 mouse colony, and genotyped the mice	oversaw the organization of the a 2 d-1 mouse colony, and genotyped the mice	Performed the experiments	Investigation|Supervision	YES
4938030	27377724	W.M.	2	performed and analysed all electrophysiology experiments	performed and analysed all electrophysiology experiments	Performed the experiments	Investigation	YES
5688050	29143239	All	PLoS52	data are shown in figures and tables within this article	data are shown in figures and tables within this article	-	Visualization	YES
5688050	29143239	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5688050	29143239	CXZ	PLoS52	designed the work, analyzed the data and reviewed and edited the manuscript	designed the work, analyzed the data and reviewed and edited the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5688050	29143239	DZY	PLoS52	designed the work, analyzed the data and reviewed and edited the manuscript	designed the work, analyzed the data and reviewed and edited the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5688050	29143239	LJ	PLoS52	designed the work, analyzed the data and reviewed and edited the manuscript|wrote the manuscript|performed the experiments	designed the work, analyzed the data and reviewed and edited the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5688050	29143239	LJ	PLoS52	designed the work, analyzed the data and reviewed and edited the manuscript|wrote the manuscript|performed the experiments	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5688050	29143239	LJ	PLoS52	designed the work, analyzed the data and reviewed and edited the manuscript|wrote the manuscript|performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5688050	29143239	SBR	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5688050	29143239	SXY	PLoS52	designed the work, analyzed the data and reviewed and edited the manuscript	designed the work, analyzed the data and reviewed and edited the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5688050	29143239	The authors	PLoS52	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5688050	29143239	XW	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5688050	29143239	ZXM	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
1975472	17878944	IJ	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1975472	17878944	IJ	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1975472	17878944	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1975472	17878944	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1975472	17878944	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1975472	17878944	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1975472	17878944	MS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1975472	17878944	MS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416827	25932644	AHM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416827	25932644	AHM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4416827	25932644	AHM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416827	25932644	NRH	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416827	25932644	NRH	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416827	25932644	NRH	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416827	25932644	NRH	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416827	25932644	SAA	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416827	25932644	ZB	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416827	25932644	ZB	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3167346	21556122	AM	2	patient clinical information supply, manuscript drafting	patient clinical information supply, manuscript drafting	Wrote the paper	Writing - Original Draft	YES
3167346	21556122	BK	2	participation in the histopathological evaluation, manuscript drafting	participation in the histopathological evaluation, manuscript drafting	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3167346	21556122	DT	2	participation in the histopathological evaluation, outlined manuscript general concept outlining, manuscript drafting and revision	participation in the histopathological evaluation, outlined manuscript general concept outlining, manuscript drafting and revision	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
3167346	21556122	MPB	2	literature search, photomicrographs acquisition, material preparation	literature search, photomicrographs acquisition, material preparation	-	Formal analysis	YES
3167346	21556122	TB	2	histopathological evaluation, manuscript writing and revision	histopathological evaluation, manuscript writing and revision	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
3167346	21556122	ZM	2	literature search, photomicrographs acquisition, material preparation	literature search, photomicrographs acquisition, material preparation	-	Formal analysis	YES
6270726	24727420	A.R.D.	PLoS5	Conceived, designed the experiments and contributed reagents/materials/analysis tools	Conceived, designed the experiments and contributed reagents/materials/analysis tools	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceptualization|Methodology|Resources	YES
6270726	24727420	A.T.V.	PLoS5	Conceived, designed the experiments and contributed reagents/materials/analysis tools|Analyzed the data and wrote the paper	Conceived, designed the experiments and contributed reagents/materials/analysis tools	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceptualization|Methodology|Resources	YES
6270726	24727420	A.T.V.	PLoS5	Conceived, designed the experiments and contributed reagents/materials/analysis tools|Analyzed the data and wrote the paper	Analyzed the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6270726	24727420	C.A.D.	PLoS5	Performed the experiments|Analyzed the data and wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
6270726	24727420	C.A.D.	PLoS5	Performed the experiments|Analyzed the data and wrote the paper	Analyzed the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6270726	24727420	E.S.C.	PLoS5	Conceived, designed the experiments and contributed reagents/materials/analysis tools|Analyzed the data and wrote the paper	Conceived, designed the experiments and contributed reagents/materials/analysis tools	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceptualization|Methodology|Resources	YES
6270726	24727420	E.S.C.	PLoS5	Conceived, designed the experiments and contributed reagents/materials/analysis tools|Analyzed the data and wrote the paper	Analyzed the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6270726	24727420	H.N.	PLoS5	Performed the experiments|Conceived, designed the experiments and contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
6270726	24727420	H.N.	PLoS5	Performed the experiments|Conceived, designed the experiments and contributed reagents/materials/analysis tools	Conceived, designed the experiments and contributed reagents/materials/analysis tools	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceptualization|Methodology|Resources	YES
6270726	24727420	J.C.M.	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
6270726	24727420	J.M.S.P.	PLoS5	Conceived, designed the experiments and contributed reagents/materials/analysis tools	Conceived, designed the experiments and contributed reagents/materials/analysis tools	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceptualization|Methodology|Resources	YES
5808222	29467778	All authors	PLoS52	approved the final version of the manuscript	approved the final version of the manuscript	-	-	NO
5808222	29467778	CL	PLoS52	conceived and designed the research project|wrote the manuscript	conceived and designed the research project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5808222	29467778	CL	PLoS52	conceived and designed the research project|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5808222	29467778	DH	PLoS52	conceived and designed the research project|analyzed the data	conceived and designed the research project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5808222	29467778	DH	PLoS52	conceived and designed the research project|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5808222	29467778	RR	PLoS52	conceived and designed the research project|performed field and laboratory work|analyzed the data|wrote the manuscript	conceived and designed the research project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5808222	29467778	RR	PLoS52	conceived and designed the research project|performed field and laboratory work|analyzed the data|wrote the manuscript	performed field and laboratory work	Performed the experiments	Investigation	YES
5808222	29467778	RR	PLoS52	conceived and designed the research project|performed field and laboratory work|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5808222	29467778	RR	PLoS52	conceived and designed the research project|performed field and laboratory work|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5808222	29467778	TD	PLoS52	performed field and laboratory work|analyzed the data	performed field and laboratory work	Performed the experiments	Investigation	YES
5808222	29467778	TD	PLoS52	performed field and laboratory work|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
6213283	30209240	AA	2	conceived the project|procured funding|designed experiments|contributed to circuit tracing|wrote the manuscript with input from all co-authors	conceived the project	Conceived and designed the experiments	Conceptualization	YES
6213283	30209240	AA	2	conceived the project|procured funding|designed experiments|contributed to circuit tracing|wrote the manuscript with input from all co-authors	procured funding	-	Funding acquisition	YES
6213283	30209240	AA	2	conceived the project|procured funding|designed experiments|contributed to circuit tracing|wrote the manuscript with input from all co-authors	designed experiments	Conceived and designed the experiments	Methodology	YES
6213283	30209240	AA	2	conceived the project|procured funding|designed experiments|contributed to circuit tracing|wrote the manuscript with input from all co-authors	contributed to circuit tracing	-	-	NO
6213283	30209240	AA	2	conceived the project|procured funding|designed experiments|contributed to circuit tracing|wrote the manuscript with input from all co-authors	wrote the manuscript with input from all co-authors	Wrote the paper	Writing - Original Draft	YES
6213283	30209240	CP	2	determined monoamine levels	determined monoamine levels	-	-	NO
6213283	30209240	EK	2	contributed unique reagents and transgenic mouse lines	contributed unique reagents and transgenic mouse lines	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
6213283	30209240	ET	2	conducted and analyzed single-cell rna seq data	conducted and analyzed single-cell rna seq data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6213283	30209240	FE	2	contributed unique reagents and transgenic mouse lines	contributed unique reagents and transgenic mouse lines	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
6213283	30209240	GA	2	gz assayed behavioral phenotypes	gz assayed behavioral phenotypes	Performed the experiments	Investigation	YES
6213283	30209240	GL	2	contributed unique reagents and transgenic mouse lines	contributed unique reagents and transgenic mouse lines	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
6213283	30209240	GSp	2	contributed unique reagents and transgenic mouse lines	contributed unique reagents and transgenic mouse lines	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
6213283	30209240	GSz	2	contributed unique reagents and transgenic mouse lines	contributed unique reagents and transgenic mouse lines	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
6213283	30209240	JB	2	contributed to circuit tracing	contributed to circuit tracing	-	-	NO
6213283	30209240	JH	2	performed quantitative neuroanatomy and circuit tracing	performed quantitative neuroanatomy and circuit tracing	Performed the experiments	Investigation	YES
6213283	30209240	KM	2	contributed unique reagents and transgenic mouse lines	contributed unique reagents and transgenic mouse lines	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
6213283	30209240	MB	2	conducted and analyzed patch-clamp electrophysiology and chemogenetics	conducted and analyzed patch-clamp electrophysiology and chemogenetics	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6213283	30209240	MP	2	contributed human subject cohort	contributed human subject cohort	-	-	NO
6213283	30209240	PZ	2	designed experiments|performed quantitative neuroanatomy and circuit tracing	designed experiments	Conceived and designed the experiments	Methodology	YES
6213283	30209240	PZ	2	designed experiments|performed quantitative neuroanatomy and circuit tracing	performed quantitative neuroanatomy and circuit tracing	Performed the experiments	Investigation	YES
6213283	30209240	RAR	2	designed experiments|conducted and analyzed patch-clamp electrophysiology and chemogenetics|conducted and analyzed single-cell rna seq data	designed experiments	Conceived and designed the experiments	Methodology	YES
6213283	30209240	RAR	2	designed experiments|conducted and analyzed patch-clamp electrophysiology and chemogenetics|conducted and analyzed single-cell rna seq data	conducted and analyzed patch-clamp electrophysiology and chemogenetics	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6213283	30209240	RAR	2	designed experiments|conducted and analyzed patch-clamp electrophysiology and chemogenetics|conducted and analyzed single-cell rna seq data	conducted and analyzed single-cell rna seq data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6213283	30209240	ROT	2	contributed unique reagents and transgenic mouse lines	contributed unique reagents and transgenic mouse lines	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
6213283	30209240	SK	2	conducted and analyzed patch-clamp electrophysiology and chemogenetics	conducted and analyzed patch-clamp electrophysiology and chemogenetics	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6213283	30209240	TGMH	2	procured funding|designed experiments	procured funding	-	Funding acquisition	YES
6213283	30209240	TGMH	2	procured funding|designed experiments	designed experiments	Conceived and designed the experiments	Methodology	YES
6213283	30209240	TH	2	conceived the project|procured funding|designed experiments|wrote the manuscript with input from all co-authors	conceived the project	Conceived and designed the experiments	Conceptualization	YES
6213283	30209240	TH	2	conceived the project|procured funding|designed experiments|wrote the manuscript with input from all co-authors	procured funding	-	Funding acquisition	YES
6213283	30209240	TH	2	conceived the project|procured funding|designed experiments|wrote the manuscript with input from all co-authors	designed experiments	Conceived and designed the experiments	Methodology	YES
6213283	30209240	TH	2	conceived the project|procured funding|designed experiments|wrote the manuscript with input from all co-authors	wrote the manuscript with input from all co-authors	Wrote the paper	Writing - Original Draft	YES
6213283	30209240	TLH	2	procured funding|designed experiments	procured funding	-	Funding acquisition	YES
6213283	30209240	TLH	2	procured funding|designed experiments	designed experiments	Conceived and designed the experiments	Methodology	YES
6213283	30209240	TRAP	2	and histochemistry	and histochemistry	Performed the experiments	Investigation	YES
6213283	30209240	ZH	2	performed quantitative neuroanatomy and circuit tracing	performed quantitative neuroanatomy and circuit tracing	Performed the experiments	Investigation	YES
6213283	30209240	ZM	2	contributed unique reagents and transgenic mouse lines	contributed unique reagents and transgenic mouse lines	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
1975473	17878953	JA	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1975473	17878953	JA	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1975473	17878953	JG	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1975473	17878953	JK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1975473	17878953	LD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1975473	17878953	LD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1975473	17878953	LD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1975473	17878953	LD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1975473	17878953	RD	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1975473	17878953	RM	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1975473	17878953	RM	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5755132	29304755	ABA	2	performed nucleic acid extraction and generated the dilution series|generated rrbs libraries|collected the clinical samples, derived and maintained the pdtx samples	performed nucleic acid extraction and generated the dilution series	Performed the experiments	Investigation	YES
5755132	29304755	ABA	2	performed nucleic acid extraction and generated the dilution series|generated rrbs libraries|collected the clinical samples, derived and maintained the pdtx samples	generated rrbs libraries	Performed the experiments	Investigation	YES
5755132	29304755	ABA	2	performed nucleic acid extraction and generated the dilution series|generated rrbs libraries|collected the clinical samples, derived and maintained the pdtx samples	collected the clinical samples, derived and maintained the pdtx samples	Performed the experiments	Investigation	YES
5755132	29304755	ABR	2	conceived the study|collected the clinical samples, derived and maintained the pdtx samples	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5755132	29304755	ABR	2	conceived the study|collected the clinical samples, derived and maintained the pdtx samples	collected the clinical samples, derived and maintained the pdtx samples	Performed the experiments	Investigation	YES
5755132	29304755	CC	2	conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5755132	29304755	CH	2	conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5755132	29304755	HC	2	contributed to data analysis	contributed to data analysis	Analyzed the data	Formal analysis	YES
5755132	29304755	MC	2	conceived the study|developed the computational approach and performed the analyses|drafted the manuscript, all authors revised and approved the final manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5755132	29304755	MC	2	conceived the study|developed the computational approach and performed the analyses|drafted the manuscript, all authors revised and approved the final manuscript	developed the computational approach and performed the analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5755132	29304755	MC	2	conceived the study|developed the computational approach and performed the analyses|drafted the manuscript, all authors revised and approved the final manuscript	drafted the manuscript, all authors revised and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5755132	29304755	OR	2	conceived the study|contributed to data analysis	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5755132	29304755	OR	2	conceived the study|contributed to data analysis	contributed to data analysis	Analyzed the data	Formal analysis	YES
5755132	29304755	RB	2	contributed to data analysis	contributed to data analysis	Analyzed the data	Formal analysis	YES
5755132	29304755	SFC	2	generated rrbs libraries	generated rrbs libraries	Performed the experiments	Investigation	YES
5755132	29304755	SJS	2	contributed to data analysis	contributed to data analysis	Analyzed the data	Formal analysis	YES
5755132	29304755	WG	2	collected the clinical samples, derived and maintained the pdtx samples	collected the clinical samples, derived and maintained the pdtx samples	Performed the experiments	Investigation	YES
5688055	29143238	All authors	2	contributed in this work|read and approved the final manuscript|agree to submit the work	contributed in this work	-	-	NO
5688055	29143238	All authors	2	contributed in this work|read and approved the final manuscript|agree to submit the work	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5688055	29143238	All authors	2	contributed in this work|read and approved the final manuscript|agree to submit the work	agree to submit the work	-	-	NO
5688055	29143238	BR	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5688055	29143238	FR	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5688055	29143238	IB	2	wrote the manuscript|performed manuscript editing and final improvement	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5688055	29143238	IB	2	wrote the manuscript|performed manuscript editing and final improvement	performed manuscript editing and final improvement	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5688055	29143238	JL	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5688055	29143238	LS	2	designed the project and analyzed the data|wrote the manuscript|performed manuscript editing and final improvement	designed the project and analyzed the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5688055	29143238	LS	2	designed the project and analyzed the data|wrote the manuscript|performed manuscript editing and final improvement	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5688055	29143238	LS	2	designed the project and analyzed the data|wrote the manuscript|performed manuscript editing and final improvement	performed manuscript editing and final improvement	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5688055	29143238	NMR	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5688055	29143238	RR	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5688055	29143238	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5688055	29143238	VS	2	designed the project and analyzed the data	designed the project and analyzed the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
4416879	25933065	AB	PLoS5	Wrote the paper|Contributed to writing and revising the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416879	25933065	AB	PLoS5	Wrote the paper|Contributed to writing and revising the paper	Contributed to writing and revising the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4416879	25933065	AKS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to writing and revising the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416879	25933065	AKS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to writing and revising the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416879	25933065	AKS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to writing and revising the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416879	25933065	AKS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to writing and revising the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416879	25933065	AKS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Contributed to writing and revising the paper	Contributed to writing and revising the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4416879	25933065	HLT	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper|Anonymised and de-identified prior to analysis|Contributed to writing and revising the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416879	25933065	HLT	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper|Anonymised and de-identified prior to analysis|Contributed to writing and revising the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416879	25933065	HLT	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper|Anonymised and de-identified prior to analysis|Contributed to writing and revising the paper	Anonymised and de-identified prior to analysis	Performed the experiments	Investigation	YES
4416879	25933065	HLT	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper|Anonymised and de-identified prior to analysis|Contributed to writing and revising the paper	Contributed to writing and revising the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4416879	25933065	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Analysed data and contributed to patient pathways|Contributed to writing and revising the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416879	25933065	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Analysed data and contributed to patient pathways|Contributed to writing and revising the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416879	25933065	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Analysed data and contributed to patient pathways|Contributed to writing and revising the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416879	25933065	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Analysed data and contributed to patient pathways|Contributed to writing and revising the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416879	25933065	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Analysed data and contributed to patient pathways|Contributed to writing and revising the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416879	25933065	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Analysed data and contributed to patient pathways|Contributed to writing and revising the paper	Analysed data and contributed to patient pathways	Analyzed the data	Formal analysis	YES
4416879	25933065	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Analysed data and contributed to patient pathways|Contributed to writing and revising the paper	Contributed to writing and revising the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4416879	25933065	MR	PLoS5	Wrote the paper|Contributed to writing and revising the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416879	25933065	MR	PLoS5	Wrote the paper|Contributed to writing and revising the paper	Contributed to writing and revising the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4958938	27431522	All authors	2	helped draft the manuscript and gave final approval for publication	helped draft the manuscript and gave final approval for publication	Wrote the paper	Writing - Original Draft	YES
4958938	27431522	B.K.	2	conceived of the study and designed the research agenda	conceived of the study and designed the research agenda	Conceived and designed the experiments	Conceptualization|Methodology	YES
4958938	27431522	E.L.	2	conceived of the study and designed the research agenda|conducted the modelling and analysed the data	conceived of the study and designed the research agenda	Conceived and designed the experiments	Conceptualization|Methodology	YES
4958938	27431522	E.L.	2	conceived of the study and designed the research agenda|conducted the modelling and analysed the data	conducted the modelling and analysed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
4958938	27431522	P.L.C.	2	conceived of the study and designed the research agenda	conceived of the study and designed the research agenda	Conceived and designed the experiments	Conceptualization|Methodology	YES
4958938	27431522	W.C.R.	2	conceived of the study and designed the research agenda	conceived of the study and designed the research agenda	Conceived and designed the experiments	Conceptualization|Methodology	YES
3167347	21556117	JY	2	defined the research theme and designed methods	defined the research theme and designed methods	Conceived and designed the experiments|Performed the experiments	Methodology	YES
3167347	21556117	SH	2	carried out the laboratory experiments, analyzed and interpreted the results, discussed analyses and wrote the paper	carried out the laboratory experiments, analyzed and interpreted the results, discussed analyses and wrote the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
1975670	17878945	AS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1975670	17878945	AS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1975670	17878945	AS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1975670	17878945	BG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1975670	17878945	BG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1975670	17878945	BG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1975670	17878945	EL	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1975670	17878945	EL	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1975670	17878945	JG	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1975670	17878945	JG	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1975670	17878945	JS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1975670	17878945	JS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1975670	17878945	JS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1975670	17878945	NV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1975670	17878945	NV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1975670	17878945	NV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1975670	17878945	NV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1975670	17878945	SD	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1975670	17878945	SD	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1975670	17878945	SR	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1975670	17878945	SR	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270727	24448061	Hazrulrizawati Hamid	1	Acquisition of data|Analysis and interpretation of data|Drafting of manuscript	Acquisition of data	Performed the experiments	Investigation	YES
6270727	24448061	Hazrulrizawati Hamid	1	Acquisition of data|Analysis and interpretation of data|Drafting of manuscript	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
6270727	24448061	Hazrulrizawati Hamid	1	Acquisition of data|Analysis and interpretation of data|Drafting of manuscript	Drafting of manuscript	Wrote the paper	Writing - Original Draft	YES
6270727	24448061	Mashitah Yusoff	1	Study conception and design|Analysis and interpretation of data|Drafting of manuscript	Study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6270727	24448061	Mashitah Yusoff	1	Study conception and design|Analysis and interpretation of data|Drafting of manuscript	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
6270727	24448061	Mashitah Yusoff	1	Study conception and design|Analysis and interpretation of data|Drafting of manuscript	Drafting of manuscript	Wrote the paper	Writing - Original Draft	YES
6270727	24448061	Peter Houghton	1	Critical revision	Critical revision	Wrote the paper	Writing - Review & Editing	YES
4416880	25932952	AMJB	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416880	25932952	BAV	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416880	25932952	BAV	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416880	25932952	CW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416880	25932952	GB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416880	25932952	GB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416880	25932952	GB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416880	25932952	HBY	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416880	25932952	HBY	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416880	25932952	JAW	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416880	25932952	JM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416880	25932952	KJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416880	25932952	KJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416880	25932952	KJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416880	25932952	KSB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416880	25932952	KSB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4416880	25932952	KSB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416880	25932952	NRR	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416880	25932952	OP	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416880	25932952	VM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416880	25932952	VM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416880	25932952	VM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416880	25932952	VM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416880	25932952	VSC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416880	25932952	VSC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4416880	25932952	VSC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416880	25932952	WG	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416880	25932952	XW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416880	25932952	XW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416880	25932952	XW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416880	25932952	XW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416880	25932952	YN	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5689044	29147976	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5689044	29147976	DE	2	carried out the chemical analyses	carried out the chemical analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5689044	29147976	FC	2	carried out the chemical analyses	carried out the chemical analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5689044	29147976	FM	2	carried out the chemical analyses	carried out the chemical analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5689044	29147976	GR	2	carried out the design of the study and drafted the manuscript|performed the molecular analyses	carried out the design of the study and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5689044	29147976	GR	2	carried out the design of the study and drafted the manuscript|performed the molecular analyses	performed the molecular analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5689044	29147976	MB	2	carried out the design of the study and drafted the manuscript	carried out the design of the study and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5689044	29147976	MCC	2	carried out the design of the study and drafted the manuscript	carried out the design of the study and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5689044	29147976	MD	2	carried out microbiological analyses	carried out microbiological analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5689044	29147976	MGF	2	carried out the design of the study and drafted the manuscript	carried out the design of the study and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5689044	29147976	MQ	2	performed the molecular analyses	performed the molecular analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5689044	29147976	TS	2	carried out microbiological analyses	carried out microbiological analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5755313	29301490	All authors	2	contributed to revisions	contributed to revisions	Wrote the paper	Writing - Review & Editing	YES
5755313	29301490	G.V.A.	2	prepared the library of samples for illumina sequencing	prepared the library of samples for illumina sequencing	Performed the experiments	Investigation	YES
5755313	29301490	M.E.S.	2	conceived and designed experiments and analyzed data|performed experiments and wrote the first draft of the manuscript	conceived and designed experiments and analyzed data	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
5755313	29301490	M.E.S.	2	conceived and designed experiments and analyzed data|performed experiments and wrote the first draft of the manuscript	performed experiments and wrote the first draft of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5755313	29301490	M.V.M.	2	conceived and designed experiments and analyzed data	conceived and designed experiments and analyzed data	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
6213284	30275266	DC	2	provided technical assistance	provided technical assistance	Performed the experiments	Investigation	YES
6213284	30275266	IC	2	conceived the study and designed experiments|wrote the manuscript	conceived the study and designed experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6213284	30275266	IC	2	conceived the study and designed experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6213284	30275266	NF	2	conceived the study and designed experiments|performed experiments and analyzed the data|wrote the manuscript	conceived the study and designed experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6213284	30275266	NF	2	conceived the study and designed experiments|performed experiments and analyzed the data|wrote the manuscript	performed experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6213284	30275266	NF	2	conceived the study and designed experiments|performed experiments and analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6213284	30275266	SRT	2	assisted in data interpretation	assisted in data interpretation	Analyzed the data	Formal analysis	YES
5808244	29467772	All the authors	2	improved upon successive versions	improved upon successive versions	-	-	NO
5808244	29467772	FM	2	conceived the manuscript	conceived the manuscript	Conceived and designed the experiments	Conceptualization	YES
5808244	29467772	MR	2	conceived the manuscript	conceived the manuscript	Conceived and designed the experiments	Conceptualization	YES
5808244	29467772	The authors	2	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	Performed the experiments	Investigation	YES
1975671	17878946	DP	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1975671	17878946	DP	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1975671	17878946	SN	PLoS5	Performed the experiments|Discussed analysis of data	Performed the experiments	Performed the experiments	Investigation	YES
1975671	17878946	SN	PLoS5	Performed the experiments|Discussed analysis of data	Discussed analysis of data	Analyzed the data	Formal analysis	YES
1975671	17878946	SP	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1975671	17878946	SP	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4637039	26582468	Qi Shen	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
4637039	26582468	Zhongrun Qian	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
4971179	27481779	A.H.C.M.	2	coordinated the project, with all authors writing individual sections and then reviewing the complete manuscript	coordinated the project, with all authors writing individual sections and then reviewing the complete manuscript	Wrote the paper	Project administration|Writing - Original Draft|Writing - Review & Editing	YES
4971179	27481779	H.C.J.G.	2	coordinated the project, with all authors writing individual sections and then reviewing the complete manuscript	coordinated the project, with all authors writing individual sections and then reviewing the complete manuscript	Wrote the paper	Project administration|Writing - Original Draft|Writing - Review & Editing	YES
4416882	25932630	CHY	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416882	25932630	GYC	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416882	25932630	HWD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416882	25932630	HWD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416882	25932630	HWD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416882	25932630	LLS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416882	25932630	LLS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4416882	25932630	LLS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416882	25932630	LQZ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416882	25932630	PC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416882	25932630	WKY	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416882	25932630	YBZ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416882	25932630	YPX	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5755412	29301493	AMG	2	contributed equally to this paper|constructed cosmid library	contributed equally to this paper	-	-	NO
5755412	29301493	AMG	2	contributed equally to this paper|constructed cosmid library	constructed cosmid library	Performed the experiments	Investigation	YES
5755412	29301493	BIC	2	provided the strains and description of the isolations	provided the strains and description of the isolations	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5755412	29301493	DS	2	helped with the with the	helped with the with the	-	-	NO
5755412	29301493	GVM	2	helped with the with the|prepared purified dna for sequencing|constructed cosmid library	helped with the with the	-	-	NO
5755412	29301493	GVM	2	helped with the with the|prepared purified dna for sequencing|constructed cosmid library	prepared purified dna for sequencing	Performed the experiments	Investigation	YES
5755412	29301493	GVM	2	helped with the with the|prepared purified dna for sequencing|constructed cosmid library	constructed cosmid library	Performed the experiments	Investigation	YES
5755412	29301493	JBJ	2	designed the study, performed analyses including plasmid comparisons and wrote the manuscript	designed the study, performed analyses including plasmid comparisons and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5755412	29301493	JCHT	2	contributed equally to this paper|assembled pacbio reads, conducted sequence analyses and contributed to writing of the manuscript	contributed equally to this paper	-	-	NO
5755412	29301493	JCHT	2	contributed equally to this paper|assembled pacbio reads, conducted sequence analyses and contributed to writing of the manuscript	assembled pacbio reads, conducted sequence analyses and contributed to writing of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5755412	29301493	NJ	2	contributed to the sequencing of the strain using other next-generation sequencing methods	contributed to the sequencing of the strain using other next-generation sequencing methods	Performed the experiments	Investigation	YES
5755412	29301493	NP	2	designed the study, performed analyses including plasmid comparisons and wrote the manuscript	designed the study, performed analyses including plasmid comparisons and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5755412	29301493	NW	2	contributed to the sequencing of the strain using other next-generation sequencing methods	contributed to the sequencing of the strain using other next-generation sequencing methods	Performed the experiments	Investigation	YES
6270728	24945578	A.I.	PLoS52	performed research and analyzed the data	performed research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270728	24945578	A.T.	PLoS52	designed research|performed research and analyzed the data|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
6270728	24945578	A.T.	PLoS52	designed research|performed research and analyzed the data|wrote the paper	performed research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270728	24945578	A.T.	PLoS52	designed research|performed research and analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270728	24945578	H.H.	PLoS52	performed research and analyzed the data	performed research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270728	24945578	H.I.	PLoS52	performed research and analyzed the data	performed research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270728	24945578	H.K.	PLoS52	designed research	designed research	Conceived and designed the experiments	Methodology	YES
6270728	24945578	H.T.	PLoS52	performed research and analyzed the data	performed research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270728	24945578	K.O.	PLoS52	designed research	designed research	Conceived and designed the experiments	Methodology	YES
6270728	24945578	K.S.	PLoS52	designed research|performed research and analyzed the data|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
6270728	24945578	K.S.	PLoS52	designed research|performed research and analyzed the data|wrote the paper	performed research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270728	24945578	K.S.	PLoS52	designed research|performed research and analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270728	24945578	Q.Z.	PLoS52	designed research|performed research and analyzed the data|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
6270728	24945578	Q.Z.	PLoS52	designed research|performed research and analyzed the data|wrote the paper	performed research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270728	24945578	Q.Z.	PLoS52	designed research|performed research and analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270728	24945578	R.Y.	PLoS52	performed research and analyzed the data	performed research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270728	24945578	Y.M.	PLoS52	performed research and analyzed the data	performed research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5691826	29150724	All	PLoS52	patients provided written consent prior to sample collection	patients provided written consent prior to sample collection	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Resources|Writing - Original Draft	YES
5691826	29150724	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5691826	29150724	CW	PLoS52	conceived of the study|wrote the paper	conceived of the study	Conceived and designed the experiments	Conceptualization	YES
5691826	29150724	CW	PLoS52	conceived of the study|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5691826	29150724	HQ	PLoS52	performed experiment, computational analysis	performed experiment, computational analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5691826	29150724	JZ	PLoS52	performed experiment, computational analysis	performed experiment, computational analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5691826	29150724	KH	PLoS52	performed experiment, computational analysis	performed experiment, computational analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5691826	29150724	ML	PLoS52	performed experiment, computational analysis|wrote the paper	performed experiment, computational analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5691826	29150724	ML	PLoS52	performed experiment, computational analysis|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5691826	29150724	The authors	PLoS52	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5691826	29150724	XZ	PLoS52	performed experiment, computational analysis	performed experiment, computational analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5691826	29150724	YK	PLoS52	performed experiment, computational analysis	performed experiment, computational analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5808252	29467776	All authors	2	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
1975672	17878947	AW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1975672	17878947	AW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1975672	17878947	AW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1975672	17878947	CC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1975672	17878947	CC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1975672	17878947	CC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4971180	27481780	C.C.M.B.	2	conceived of the general theme of the paper|organized and drafted the initial outline, and all authors wrote and revised the manuscript	conceived of the general theme of the paper	Conceived and designed the experiments	Conceptualization	YES
4971180	27481780	C.C.M.B.	2	conceived of the general theme of the paper|organized and drafted the initial outline, and all authors wrote and revised the manuscript	organized and drafted the initial outline, and all authors wrote and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4971180	27481780	N.E.P.	2	conceived of the general theme of the paper|organized and drafted the initial outline, and all authors wrote and revised the manuscript	conceived of the general theme of the paper	Conceived and designed the experiments	Conceptualization	YES
4971180	27481780	N.E.P.	2	conceived of the general theme of the paper|organized and drafted the initial outline, and all authors wrote and revised the manuscript	organized and drafted the initial outline, and all authors wrote and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6276876	30442834	CN	2	in collaboration	in collaboration	-	-	NO
6276876	30442834	PT	2	in collaboration	in collaboration	-	-	NO
3167350	21556119	CB	2	contributed equally to the work	contributed equally to the work	-	-	NO
3167350	21556119	DW	2	contributed equally to the work	contributed equally to the work	-	-	NO
1975673	17878937	HT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1975673	17878937	HT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1975673	17878937	HT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1975673	17878937	JW	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1975673	17878937	SZ	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1975673	17878937	SZ	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416883	25933411	AA	PLoS5	Performed the experiments|Contributed to revising the manuscript critically for important intellectual content	Performed the experiments	Performed the experiments	Investigation	YES
4416883	25933411	AA	PLoS5	Performed the experiments|Contributed to revising the manuscript critically for important intellectual content	Contributed to revising the manuscript critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4416883	25933411	CAB	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416883	25933411	CAB	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416883	25933411	CBW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416883	25933411	CBW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416883	25933411	CBW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416883	25933411	CHC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416883	25933411	CHC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416883	25933411	CHC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416883	25933411	CHC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416883	25933411	HWL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416883	25933411	HWL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416883	25933411	HWL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416883	25933411	JTN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416883	25933411	JTN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416883	25933411	JTN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416883	25933411	JTN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416883	25933411	KRD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416883	25933411	KRD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416883	25933411	KRD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416883	25933411	KRD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416883	25933411	KS	PLoS5	Analyzed the data|Contributed to revising the manuscript critically for important intellectual content	Analyzed the data	Analyzed the data	Formal analysis	YES
4416883	25933411	KS	PLoS5	Analyzed the data|Contributed to revising the manuscript critically for important intellectual content	Contributed to revising the manuscript critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4416883	25933411	MAPP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416883	25933411	MAPP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416883	25933411	MAPP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416883	25933411	MB	PLoS5	Analyzed the data|Contributed to revising the manuscript critically for important intellectual content	Analyzed the data	Analyzed the data	Formal analysis	YES
4416883	25933411	MB	PLoS5	Analyzed the data|Contributed to revising the manuscript critically for important intellectual content	Contributed to revising the manuscript critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
3167351	21556115	All authors	2	approve the final version	approve the final version	-	-	NO
3167351	21556115	all authors	2	contributed to the planning of this study, experimental procedures, analysis of data obtained and in the writing of this paper	contributed to the planning of this study, experimental procedures, analysis of data obtained and in the writing of this paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
5755439	29304732	AS	2	wrote the manuscript and analyzed the results|contributed to the design of the study	wrote the manuscript and analyzed the results	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5755439	29304732	AS	2	wrote the manuscript and analyzed the results|contributed to the design of the study	contributed to the design of the study	Conceived and designed the experiments	Methodology	YES
5755439	29304732	All authors	2	were involved in drafting and revising the manuscript	were involved in drafting and revising the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5755439	29304732	CH	2	wrote the manuscript and analyzed the results|contributed to the design of the study|coordinated the projects	wrote the manuscript and analyzed the results	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5755439	29304732	CH	2	wrote the manuscript and analyzed the results|contributed to the design of the study|coordinated the projects	contributed to the design of the study	Conceived and designed the experiments	Methodology	YES
5755439	29304732	CH	2	wrote the manuscript and analyzed the results|contributed to the design of the study|coordinated the projects	coordinated the projects	-	Project administration	YES
5755439	29304732	JQ	2	conducted the physical mapping of the de novo sequenced genome and genome collinear analyses|wrote the manuscript and analyzed the results	conducted the physical mapping of the de novo sequenced genome and genome collinear analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5755439	29304732	JQ	2	conducted the physical mapping of the de novo sequenced genome and genome collinear analyses|wrote the manuscript and analyzed the results	wrote the manuscript and analyzed the results	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5755439	29304732	JZ	2	contributed to the design of the study|contributed to the annotation and phylogeny analyses of genes located in the mating type loci|coordinated the projects	contributed to the design of the study	Conceived and designed the experiments	Methodology	YES
5755439	29304732	JZ	2	contributed to the design of the study|contributed to the annotation and phylogeny analyses of genes located in the mating type loci|coordinated the projects	contributed to the annotation and phylogeny analyses of genes located in the mating type loci	Analyzed the data	Data curation|Formal analysis	YES
5755439	29304732	JZ	2	contributed to the design of the study|contributed to the annotation and phylogeny analyses of genes located in the mating type loci|coordinated the projects	coordinated the projects	-	Project administration	YES
5755439	29304732	QC	2	provided the parental lines and contributed to the population construction	provided the parental lines and contributed to the population construction	Performed the experiments	Investigation	YES
5755439	29304732	WG	2	carried out the genetic linkage mapping and mating type identification|conducted the physical mapping of the de novo sequenced genome and genome collinear analyses|wrote the manuscript and analyzed the results|contributed to the design of the study	carried out the genetic linkage mapping and mating type identification	Performed the experiments	Investigation	YES
5755439	29304732	WG	2	carried out the genetic linkage mapping and mating type identification|conducted the physical mapping of the de novo sequenced genome and genome collinear analyses|wrote the manuscript and analyzed the results|contributed to the design of the study	conducted the physical mapping of the de novo sequenced genome and genome collinear analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5755439	29304732	WG	2	carried out the genetic linkage mapping and mating type identification|conducted the physical mapping of the de novo sequenced genome and genome collinear analyses|wrote the manuscript and analyzed the results|contributed to the design of the study	wrote the manuscript and analyzed the results	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5755439	29304732	WG	2	carried out the genetic linkage mapping and mating type identification|conducted the physical mapping of the de novo sequenced genome and genome collinear analyses|wrote the manuscript and analyzed the results|contributed to the design of the study	contributed to the design of the study	Conceived and designed the experiments	Methodology	YES
5755439	29304732	YZ	2	carried out the mating and identification of crossings|contributed to the annotation and phylogeny analyses of genes located in the mating type loci	carried out the mating and identification of crossings	Performed the experiments	Investigation	YES
5755439	29304732	YZ	2	carried out the mating and identification of crossings|contributed to the annotation and phylogeny analyses of genes located in the mating type loci	contributed to the annotation and phylogeny analyses of genes located in the mating type loci	Analyzed the data	Data curation|Formal analysis	YES
5691827	29150728	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5691827	29150728	DC	2	designed assay and prepared the manuscript	designed assay and prepared the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5691827	29150728	JJ	2	did the experiments and collected the data	did the experiments and collected the data	Performed the experiments	Investigation	YES
5691827	29150728	MH	2	did the experiments and collected the data	did the experiments and collected the data	Performed the experiments	Investigation	YES
5691827	29150728	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
6270729	25525826	B.M.	2	carried out the experimental work	carried out the experimental work	Performed the experiments	Investigation	YES
6270729	25525826	B.S.P.	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
6270729	25525826	D.M.	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
6270729	25525826	F.C.	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
6270729	25525826	H.J.O.	2	designed the study|prepared the manuscript|coordinated the project	designed the study	Conceived and designed the experiments	Methodology	YES
6270729	25525826	H.J.O.	2	designed the study|prepared the manuscript|coordinated the project	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
6270729	25525826	H.J.O.	2	designed the study|prepared the manuscript|coordinated the project	coordinated the project	-	Project administration	YES
6270729	25525826	H.W.	2	prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
6270729	25525826	K.E.M.	2	designed the study|prepared the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
6270729	25525826	K.E.M.	2	designed the study|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
6270729	25525826	P.S.	2	carried out the experimental work	carried out the experimental work	Performed the experiments	Investigation	YES
6270729	25525826	S.D.	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
6270729	25525826	V.C.	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
6270729	25525826	Y.-F.Z.	2	carried out the experimental work	carried out the experimental work	Performed the experiments	Investigation	YES
6276879	30446597	GSS	2	conceived the study, designed experiments, analysed the data and wrote the manuscript	conceived the study, designed experiments, analysed the data and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
6276879	30446597	HW	2	conceived the study, designed experiments, analysed the data and wrote the manuscript	conceived the study, designed experiments, analysed the data and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
6276879	30446597	KRB	2	expressed and purified proteins for ubiquitination assays	expressed and purified proteins for ubiquitination assays	Performed the experiments	Investigation	YES
6276879	30446597	LK	2	helped with the design and analysis of hdx experiments	helped with the design and analysis of hdx experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6276879	30446597	NMR	2	interaction experiments, analysed the data and wrote the manuscript|experiments and hdx experiments and wrote the manuscript	interaction experiments, analysed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6276879	30446597	NMR	2	interaction experiments, analysed the data and wrote the manuscript|experiments and hdx experiments and wrote the manuscript	experiments and hdx experiments and wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6276879	30446597	UbVS	2	reactivity experiments, and analysed and wrote the manuscript	reactivity experiments, and analysed and wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6276879	30446597	VKC	2	completed ubiquitin loading and off-loading experiments and wrote the manuscript	completed ubiquitin loading and off-loading experiments and wrote the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6276879	30446597	YX	2	helped with the design and analysis of hdx experiments	helped with the design and analysis of hdx experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5808308	29467785	SNP	2	and p-sine1 markers, data analysis and manuscript writing	and p-sine1 markers, data analysis and manuscript writing	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5808308	29467785	SSR	2	and p-sine1 markers, data analysis and manuscript writing	and p-sine1 markers, data analysis and manuscript writing	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
1975674	17878936	AN	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1975674	17878936	AN	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1975674	17878936	MN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1975674	17878936	MN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1975674	17878936	MN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1975674	17878936	MN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416884	25933378	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416884	25933378	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416884	25933378	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416884	25933378	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416884	25933378	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416884	25933378	RWD	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416884	25933378	WZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416884	25933378	WZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416884	25933378	WZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416884	25933378	WZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270730	25054443	B.R.P.	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
6270730	25054443	C.S.	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
6270730	25054443	C.S.	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
6270730	25054443	C.S.	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270730	25054443	E.M.	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
6270730	25054443	E.M.	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
6270730	25054443	E.M.	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270730	25054443	F.F.	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
6270730	25054443	F.F.	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
6270730	25054443	L.R.S.	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
6270730	25054443	P.V.	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6270730	25054443	P.V.	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
6270730	25054443	P.V.	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
6270730	25054443	P.V.	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1975675	17878939	AK	PLoS5	Initiated and contributed significantly to the development of the oligonucleotides used for the microarray	Initiated and contributed significantly to the development of the oligonucleotides used for the microarray	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
1975675	17878939	EH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Set up the oligonucleotide microarray	Performed the experiments	Performed the experiments	Investigation	YES
1975675	17878939	EH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Set up the oligonucleotide microarray	Analyzed the data	Analyzed the data	Formal analysis	YES
1975675	17878939	EH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Set up the oligonucleotide microarray	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1975675	17878939	EH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Set up the oligonucleotide microarray	Set up the oligonucleotide microarray	Performed the experiments	Investigation|Methodology	YES
1975675	17878939	FM	PLoS5	Contributed to the development of the microarray|Commented on the manuscript	Contributed to the development of the microarray	Performed the experiments	Investigation	YES
1975675	17878939	FM	PLoS5	Contributed to the development of the microarray|Commented on the manuscript	Commented on the manuscript	-	-	NO
1975675	17878939	JM	PLoS5	Initiated and supervised the project|Commented on the manuscript	Initiated and supervised the project	Conceived and designed the experiments	Conceptualization|Supervision	YES
1975675	17878939	JM	PLoS5	Initiated and supervised the project|Commented on the manuscript	Commented on the manuscript	-	-	NO
1975675	17878939	JS	PLoS5	Participated in array and hybridisation planning|Participated in array and hybridisation design|Supervised the array production	Participated in array and hybridisation planning	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
1975675	17878939	JS	PLoS5	Participated in array and hybridisation planning|Participated in array and hybridisation design|Supervised the array production	Participated in array and hybridisation design	Conceived and designed the experiments|Performed the experiments	Investigation	YES
1975675	17878939	JS	PLoS5	Participated in array and hybridisation planning|Participated in array and hybridisation design|Supervised the array production	Supervised the array production	Performed the experiments	Investigation|Supervision	YES
1975675	17878939	LS	PLoS5	Contributed to data analysis	Contributed to data analysis	Analyzed the data	Formal analysis	YES
1975675	17878939	QH	PLoS5	Conceived and designed the experiments|Initiated and supervised the project|Initiated and contributed significantly to the development of the oligonucleotides used for the microarray|Wrote the manuscript with helpful discussions and comments from all co-authors	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1975675	17878939	QH	PLoS5	Conceived and designed the experiments|Initiated and supervised the project|Initiated and contributed significantly to the development of the oligonucleotides used for the microarray|Wrote the manuscript with helpful discussions and comments from all co-authors	Initiated and supervised the project	Conceived and designed the experiments	Conceptualization|Supervision	YES
1975675	17878939	QH	PLoS5	Conceived and designed the experiments|Initiated and supervised the project|Initiated and contributed significantly to the development of the oligonucleotides used for the microarray|Wrote the manuscript with helpful discussions and comments from all co-authors	Initiated and contributed significantly to the development of the oligonucleotides used for the microarray	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
1975675	17878939	QH	PLoS5	Conceived and designed the experiments|Initiated and supervised the project|Initiated and contributed significantly to the development of the oligonucleotides used for the microarray|Wrote the manuscript with helpful discussions and comments from all co-authors	Wrote the manuscript with helpful discussions and comments from all co-authors	Wrote the paper	Writing - Original Draft	YES
1975675	17878939	RS	PLoS5	Participated in array and hybridisation planning|Participated in array and hybridisation design|Supervised the array production	Participated in array and hybridisation planning	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
1975675	17878939	RS	PLoS5	Participated in array and hybridisation planning|Participated in array and hybridisation design|Supervised the array production	Participated in array and hybridisation design	Conceived and designed the experiments|Performed the experiments	Investigation	YES
1975675	17878939	RS	PLoS5	Participated in array and hybridisation planning|Participated in array and hybridisation design|Supervised the array production	Supervised the array production	Performed the experiments	Investigation|Supervision	YES
1975675	17878939	TK	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1975675	17878939	TK	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1975675	17878939	TK	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5756330	29304737	AK	2	carried out the experimental work, performed the substantial part of the data analysis, and wrote a draft of the manuscript|improved the draft of the manuscript|finally revised the draft of the manuscript	carried out the experimental work, performed the substantial part of the data analysis, and wrote a draft of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5756330	29304737	AK	2	carried out the experimental work, performed the substantial part of the data analysis, and wrote a draft of the manuscript|improved the draft of the manuscript|finally revised the draft of the manuscript	improved the draft of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5756330	29304737	AK	2	carried out the experimental work, performed the substantial part of the data analysis, and wrote a draft of the manuscript|improved the draft of the manuscript|finally revised the draft of the manuscript	finally revised the draft of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5756330	29304737	AV	2	made the rna seq data publicly available	made the rna seq data publicly available	Performed the experiments	Investigation	YES
5756330	29304737	BU	2	made the rna seq data publicly available|finally revised the draft of the manuscript	made the rna seq data publicly available	Performed the experiments	Investigation	YES
5756330	29304737	BU	2	made the rna seq data publicly available|finally revised the draft of the manuscript	finally revised the draft of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5756330	29304737	JK	2	developed the improved rna seq protocol|finally revised the draft of the manuscript	developed the improved rna seq protocol	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5756330	29304737	JK	2	developed the improved rna seq protocol|finally revised the draft of the manuscript	finally revised the draft of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5756330	29304737	MB	2	improved the draft of the manuscript|finally revised the draft of the manuscript	improved the draft of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5756330	29304737	MB	2	improved the draft of the manuscript|finally revised the draft of the manuscript	finally revised the draft of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5756330	29304737	TB	2	developed the improved rna seq protocol|finally revised the draft of the manuscript	developed the improved rna seq protocol	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5756330	29304737	TB	2	developed the improved rna seq protocol|finally revised the draft of the manuscript	finally revised the draft of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5756330	29304737	TP	2	improved the draft of the manuscript|finally revised the draft of the manuscript|coordinated the study, was involved in data analysis and finalized the manuscript	improved the draft of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5756330	29304737	TP	2	improved the draft of the manuscript|finally revised the draft of the manuscript|coordinated the study, was involved in data analysis and finalized the manuscript	finally revised the draft of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5756330	29304737	TP	2	improved the draft of the manuscript|finally revised the draft of the manuscript|coordinated the study, was involved in data analysis and finalized the manuscript	coordinated the study, was involved in data analysis and finalized the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Project administration|Writing - Review & Editing	YES
4971183	27481783	The authors	2	contributed equally to this manuscript	contributed equally to this manuscript	-	-	NO
4416885	25932912	JR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416885	25932912	JR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416885	25932912	JR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416885	25932912	JR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416885	25932912	JR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416885	25932912	RB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416885	25932912	RB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416885	25932912	RB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416885	25932912	RB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416885	25932912	RB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416885	25932912	ST	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416885	25932912	ST	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416885	25932912	ST	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416885	25932912	ST	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416885	25932912	VR	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4416885	25932912	VR	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4416885	25932912	VR	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5808325	29467787	All authors	2	participated in the experimental design and manuscript writing	participated in the experimental design and manuscript writing	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5808325	29467787	FF	2	designed the study, performed the experiment	designed the study, performed the experiment	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5808325	29467787	KS	2	collected and analyzed the data	collected and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5808325	29467787	XQ	2	designed the study, performed the experiment|collected and analyzed the data	designed the study, performed the experiment	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5808325	29467787	XQ	2	designed the study, performed the experiment|collected and analyzed the data	collected and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5808325	29467787	XW	2	collected and analyzed the data	collected and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5808325	29467787	YH	2	collected and analyzed the data	collected and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5698236	29164404	All	2	the relevant data and materials are presented in the manuscript, and there are no additional files	the relevant data and materials are presented in the manuscript, and there are no additional files	-	-	NO
5698236	29164404	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5698236	29164404	NAK	2	writing of article and guidance in the study	writing of article and guidance in the study	Wrote the paper	Supervision|Writing - Original Draft	YES
5698236	29164404	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
6276891	30389666	AE	PLoS52	designed the research|analyzed the data and discussed the results|wrote the manuscript with input from all the authors	designed the research	Conceived and designed the experiments	Methodology	YES
6276891	30389666	AE	PLoS52	designed the research|analyzed the data and discussed the results|wrote the manuscript with input from all the authors	analyzed the data and discussed the results	Analyzed the data	Formal analysis	YES
6276891	30389666	AE	PLoS52	designed the research|analyzed the data and discussed the results|wrote the manuscript with input from all the authors	wrote the manuscript with input from all the authors	Wrote the paper	Writing - Original Draft	YES
6276891	30389666	CA	PLoS52	performed the experiments|analyzed the data and discussed the results	performed the experiments	Performed the experiments	Investigation	YES
6276891	30389666	CA	PLoS52	performed the experiments|analyzed the data and discussed the results	analyzed the data and discussed the results	Analyzed the data	Formal analysis	YES
6276891	30389666	CL	PLoS52	performed the experiments|analyzed the data and discussed the results	performed the experiments	Performed the experiments	Investigation	YES
6276891	30389666	CL	PLoS52	performed the experiments|analyzed the data and discussed the results	analyzed the data and discussed the results	Analyzed the data	Formal analysis	YES
6276891	30389666	CT	PLoS52	designed the research|performed the experiments|analyzed the data and discussed the results|wrote the manuscript with input from all the authors	designed the research	Conceived and designed the experiments	Methodology	YES
6276891	30389666	CT	PLoS52	designed the research|performed the experiments|analyzed the data and discussed the results|wrote the manuscript with input from all the authors	performed the experiments	Performed the experiments	Investigation	YES
6276891	30389666	CT	PLoS52	designed the research|performed the experiments|analyzed the data and discussed the results|wrote the manuscript with input from all the authors	analyzed the data and discussed the results	Analyzed the data	Formal analysis	YES
6276891	30389666	CT	PLoS52	designed the research|performed the experiments|analyzed the data and discussed the results|wrote the manuscript with input from all the authors	wrote the manuscript with input from all the authors	Wrote the paper	Writing - Original Draft	YES
6276891	30389666	GN	PLoS52	performed the experiments|analyzed the data and discussed the results	performed the experiments	Performed the experiments	Investigation	YES
6276891	30389666	GN	PLoS52	performed the experiments|analyzed the data and discussed the results	analyzed the data and discussed the results	Analyzed the data	Formal analysis	YES
6276891	30389666	IL	PLoS52	performed the experiments|analyzed the data and discussed the results	performed the experiments	Performed the experiments	Investigation	YES
6276891	30389666	IL	PLoS52	performed the experiments|analyzed the data and discussed the results	analyzed the data and discussed the results	Analyzed the data	Formal analysis	YES
6276891	30389666	JV	PLoS52	analyzed the data and discussed the results	analyzed the data and discussed the results	Analyzed the data	Formal analysis	YES
6276891	30389666	MM	PLoS52	analyzed the data and discussed the results	analyzed the data and discussed the results	Analyzed the data	Formal analysis	YES
6276891	30389666	PS	PLoS52	analyzed the data and discussed the results	analyzed the data and discussed the results	Analyzed the data	Formal analysis	YES
6270731	25432014	IE	PLoS52	designed research|performed research and analyzed the data|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
6270731	25432014	IE	PLoS52	designed research|performed research and analyzed the data|wrote the paper	performed research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270731	25432014	IE	PLoS52	designed research|performed research and analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270731	25432014	MA	PLoS52	performed research and analyzed the data|wrote the paper	performed research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270731	25432014	MA	PLoS52	performed research and analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270731	25432014	MY	PLoS52	performed research and analyzed the data|wrote the paper	performed research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270731	25432014	MY	PLoS52	performed research and analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6371888	30842853	All authors	2	have given approval to the final version of the manuscript	have given approval to the final version of the manuscript	-	-	NO
3886280	24453873	Chris J. Watson	2	contributed equally to this work	contributed equally to this work	-	-	NO
3886280	24453873	Kenneth McDonald	2	contributed equally to this work	contributed equally to this work	-	-	NO
4416886	25933103	BJN	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416886	25933103	BJN	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416886	25933103	BJN	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416886	25933103	CN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416886	25933103	CN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416886	25933103	CN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416886	25933103	CN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416886	25933103	CN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416886	25933103	DW	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416886	25933103	MAP	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4416886	25933103	MAP	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416886	25933103	SMDS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416886	25933103	SMDS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416886	25933103	SMDS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416886	25933103	SMDS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416886	25933103	SMDS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5756342	29306326	All authors	2	read, corrected and approved the final manuscript	read, corrected and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5756342	29306326	CP	2	performed gene disruption and virulence assays, dna isolation and purification, and the different molecular biology techniques used in this study|provided guidance in the drafting of the manuscript and contributed to acquisition, analysis and interpretation of data	performed gene disruption and virulence assays, dna isolation and purification, and the different molecular biology techniques used in this study	Performed the experiments	Investigation	YES
5756342	29306326	CP	2	performed gene disruption and virulence assays, dna isolation and purification, and the different molecular biology techniques used in this study|provided guidance in the drafting of the manuscript and contributed to acquisition, analysis and interpretation of data	provided guidance in the drafting of the manuscript and contributed to acquisition, analysis and interpretation of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Supervision|Writing - Original Draft	YES
5756342	29306326	FS	2	designed the main aims of this work and wrote the manuscript|provided guidance in the drafting of the manuscript and contributed to acquisition, analysis and interpretation of data	designed the main aims of this work and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
5756342	29306326	FS	2	designed the main aims of this work and wrote the manuscript|provided guidance in the drafting of the manuscript and contributed to acquisition, analysis and interpretation of data	provided guidance in the drafting of the manuscript and contributed to acquisition, analysis and interpretation of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Supervision|Writing - Original Draft	YES
5756342	29306326	GF	2	provided guidance in the drafting of the manuscript and contributed to acquisition, analysis and interpretation of data	provided guidance in the drafting of the manuscript and contributed to acquisition, analysis and interpretation of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Supervision|Writing - Original Draft	YES
5756342	29306326	GMSL	2	provided guidance in the drafting of the manuscript and contributed to acquisition, analysis and interpretation of data	provided guidance in the drafting of the manuscript and contributed to acquisition, analysis and interpretation of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Supervision|Writing - Original Draft	YES
5756342	29306326	GV	2	provided guidance in the drafting of the manuscript and contributed to acquisition, analysis and interpretation of data	provided guidance in the drafting of the manuscript and contributed to acquisition, analysis and interpretation of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Supervision|Writing - Original Draft	YES
5756342	29306326	MMM	2	provided guidance in the drafting of the manuscript and contributed to acquisition, analysis and interpretation of data	provided guidance in the drafting of the manuscript and contributed to acquisition, analysis and interpretation of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Supervision|Writing - Original Draft	YES
5756342	29306326	MR	2	designed the main aims of this work and wrote the manuscript|performed gene disruption and virulence assays, dna isolation and purification, and the different molecular biology techniques used in this study|provided guidance in the drafting of the manuscript and contributed to acquisition, analysis and interpretation of data	designed the main aims of this work and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
5756342	29306326	MR	2	designed the main aims of this work and wrote the manuscript|performed gene disruption and virulence assays, dna isolation and purification, and the different molecular biology techniques used in this study|provided guidance in the drafting of the manuscript and contributed to acquisition, analysis and interpretation of data	performed gene disruption and virulence assays, dna isolation and purification, and the different molecular biology techniques used in this study	Performed the experiments	Investigation	YES
5756342	29306326	MR	2	designed the main aims of this work and wrote the manuscript|performed gene disruption and virulence assays, dna isolation and purification, and the different molecular biology techniques used in this study|provided guidance in the drafting of the manuscript and contributed to acquisition, analysis and interpretation of data	provided guidance in the drafting of the manuscript and contributed to acquisition, analysis and interpretation of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Supervision|Writing - Original Draft	YES
5756342	29306326	MV	2	provided guidance in the drafting of the manuscript and contributed to acquisition, analysis and interpretation of data	provided guidance in the drafting of the manuscript and contributed to acquisition, analysis and interpretation of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Supervision|Writing - Original Draft	YES
5756342	29306326	RB	2	conducted the different bioinformatic analyses|provided guidance in the drafting of the manuscript and contributed to acquisition, analysis and interpretation of data	conducted the different bioinformatic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5756342	29306326	RB	2	conducted the different bioinformatic analyses|provided guidance in the drafting of the manuscript and contributed to acquisition, analysis and interpretation of data	provided guidance in the drafting of the manuscript and contributed to acquisition, analysis and interpretation of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Supervision|Writing - Original Draft	YES
5756342	29306326	SOC	2	provided guidance in the drafting of the manuscript and contributed to acquisition, analysis and interpretation of data	provided guidance in the drafting of the manuscript and contributed to acquisition, analysis and interpretation of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Supervision|Writing - Original Draft	YES
5808326	29467773	CH	2	constructed bacterial reporter strains|conceived the study and designed experiments	constructed bacterial reporter strains	Performed the experiments	Investigation	YES
5808326	29467773	CH	2	constructed bacterial reporter strains|conceived the study and designed experiments	conceived the study and designed experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5808326	29467773	CL	2	cultivated plant lines and harvested nodules|constructed bacterial reporter strains|carried out cryosectioning, nodule staining, and microscopy|conceived the study and designed experiments|wrote the manuscript	cultivated plant lines and harvested nodules	Performed the experiments	Investigation	YES
5808326	29467773	CL	2	cultivated plant lines and harvested nodules|constructed bacterial reporter strains|carried out cryosectioning, nodule staining, and microscopy|conceived the study and designed experiments|wrote the manuscript	constructed bacterial reporter strains	Performed the experiments	Investigation	YES
5808326	29467773	CL	2	cultivated plant lines and harvested nodules|constructed bacterial reporter strains|carried out cryosectioning, nodule staining, and microscopy|conceived the study and designed experiments|wrote the manuscript	carried out cryosectioning, nodule staining, and microscopy	Performed the experiments	Investigation	YES
5808326	29467773	CL	2	cultivated plant lines and harvested nodules|constructed bacterial reporter strains|carried out cryosectioning, nodule staining, and microscopy|conceived the study and designed experiments|wrote the manuscript	conceived the study and designed experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5808326	29467773	CL	2	cultivated plant lines and harvested nodules|constructed bacterial reporter strains|carried out cryosectioning, nodule staining, and microscopy|conceived the study and designed experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5808326	29467773	LS	2	cultivated plant lines and harvested nodules|constructed bacterial reporter strains	cultivated plant lines and harvested nodules	Performed the experiments	Investigation	YES
5808326	29467773	LS	2	cultivated plant lines and harvested nodules|constructed bacterial reporter strains	constructed bacterial reporter strains	Performed the experiments	Investigation	YES
5808326	29467773	SL	2	conceived the study and designed experiments|wrote the manuscript	conceived the study and designed experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5808326	29467773	SL	2	conceived the study and designed experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5698238	29164422	All authors	2	were involved in the design of the study|read and approved the final manuscript	were involved in the design of the study	Conceived and designed the experiments	Methodology	YES
5698238	29164422	All authors	2	were involved in the design of the study|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5698238	29164422	The authors	2	contributed as follows	contributed as follows	-	-	NO
4971184	27481784	A.C.	2	participated in the design of the study and collected samples for analysis	participated in the design of the study and collected samples for analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
4971184	27481784	A.G.	2	participated in the design of the study and collected samples for analysis	participated in the design of the study and collected samples for analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
4971184	27481784	A.R.	2	participated in the design of the study and collected samples for analysis	participated in the design of the study and collected samples for analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
4971184	27481784	B.W.	2	participated in the design of the study and collected samples for analysis	participated in the design of the study and collected samples for analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
4971184	27481784	C.S.	2	participated in the design of the study and collected samples for analysis|drafted the manuscript	participated in the design of the study and collected samples for analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
4971184	27481784	C.S.	2	participated in the design of the study and collected samples for analysis|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4971184	27481784	M.C.	2	conceived of the study	conceived of the study	Conceived and designed the experiments	Conceptualization	YES
4971184	27481784	M.H.	2	conceived of the study	conceived of the study	Conceived and designed the experiments	Conceptualization	YES
4971184	27481784	Y.v.d.H.	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4971184	27481784	all authors	2	contributed to the manuscript and gave final approval for publication	contributed to the manuscript and gave final approval for publication	-	-	NO
1975676	17878929	CM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1975676	17878929	CM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1975676	17878929	CM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1975676	17878929	GD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1975676	17878929	GD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1975676	17878929	GD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1975676	17878929	JC	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1975676	17878929	JC	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1975676	17878929	SA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1975676	17878929	SA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1975676	17878929	SA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1975676	17878929	VT	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1975676	17878929	VT	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270732	24714191	AO	2	designed research	designed research	Conceived and designed the experiments	Methodology	YES
6270732	24714191	BI	2	designed research	designed research	Conceived and designed the experiments	Methodology	YES
6270732	24714191	JC	2	designed research	designed research	Conceived and designed the experiments	Methodology	YES
6270732	24714191	JG	2	designed research	designed research	Conceived and designed the experiments	Methodology	YES
6270732	24714191	JQ	2	designed research	designed research	Conceived and designed the experiments	Methodology	YES
6270732	24714191	MN	2	designed research	designed research	Conceived and designed the experiments	Methodology	YES
6270732	24714191	RA	2	designed research	designed research	Conceived and designed the experiments	Methodology	YES
6293278	30266824	APS	2	helped design and conduct mass spectrometry experiments	helped design and conduct mass spectrometry experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6293278	30266824	ARM	2	designed the experiments and wrote most of the manuscript	designed the experiments and wrote most of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
6293278	30266824	EC	2	contributed to protein purification experiments	contributed to protein purification experiments	Performed the experiments	Investigation	YES
6293278	30266824	HRF	2	helped design and conduct mass spectrometry experiments	helped design and conduct mass spectrometry experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6293278	30266824	LLB	2	designed the experiments and wrote most of the manuscript|conducted most of the experiments and analyses	designed the experiments and wrote most of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
6293278	30266824	LLB	2	designed the experiments and wrote most of the manuscript|conducted most of the experiments and analyses	conducted most of the experiments and analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6293278	30266824	MM	2	conducted some of the experiments	conducted some of the experiments	Performed the experiments	Investigation	YES
6293278	30266824	MS	2	conducted some of the experiments	conducted some of the experiments	Performed the experiments	Investigation	YES
6293278	30266824	PDN	2	designed the experiments and wrote most of the manuscript|conducted most of the experiments and analyses	designed the experiments and wrote most of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
6293278	30266824	PDN	2	designed the experiments and wrote most of the manuscript|conducted most of the experiments and analyses	conducted most of the experiments and analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6293278	30266824	SC	2	contributed to multiple experiments	contributed to multiple experiments	Performed the experiments	Investigation	YES
6293278	30266824	SKU	2	designed the experiments and wrote most of the manuscript	designed the experiments and wrote most of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4416887	25932626	BJP	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416887	25932626	BRY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416887	25932626	BRY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416887	25932626	BRY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416887	25932626	BRY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416887	25932626	HJS	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416887	25932626	JL	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416887	25932626	JL	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416887	25932626	JMS	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416887	25932626	JYS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416887	25932626	JYS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416887	25932626	MSK	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416887	25932626	NKC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416887	25932626	SP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416887	25932626	YJK	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5756345	29304754	AC	2	conducted machine learning analysis	conducted machine learning analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5756345	29304754	CC	2	made substantial contributions to conception and design of the work, in data analysis and drafting the manuscript|conducted machine learning analysis	made substantial contributions to conception and design of the work, in data analysis and drafting the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Resources|Writing - Original Draft	YES
5756345	29304754	CC	2	made substantial contributions to conception and design of the work, in data analysis and drafting the manuscript|conducted machine learning analysis	conducted machine learning analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5756345	29304754	CO	2	conducted machine learning analysis	conducted machine learning analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5756345	29304754	GBE	2	made substantial contributions to the interpretation of data	made substantial contributions to the interpretation of data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5756345	29304754	GBO	2	conducted machine learning analysis	conducted machine learning analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5756345	29304754	IC	2	made substantial contributions guiding and revising the work critically for important intellectual content and has been involved in drafting the manuscript, answering the referees comments and given final approval of the version to be published	made substantial contributions guiding and revising the work critically for important intellectual content and has been involved in drafting the manuscript, answering the referees comments and given final approval of the version to be published	Wrote the paper	Supervision|Writing - Original Draft|Writing - Review & Editing	YES
5808331	29467783	AG	2	wrote scripts and performed bioinformatic analyses	wrote scripts and performed bioinformatic analyses	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Software|Writing - Original Draft	YES
5808331	29467783	EK	2	performed molecular biology experiments, designed primers, developed rna protocols	performed molecular biology experiments, designed primers, developed rna protocols	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5808331	29467783	EL	2	performed molecular biology experiments, designed primers, developed rna protocols	performed molecular biology experiments, designed primers, developed rna protocols	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5808331	29467783	MK	2	designed the study, reviewed the results and oversaw the manuscript preparation	designed the study, reviewed the results and oversaw the manuscript preparation	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
5698239	29164352	AR	2	analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5698239	29164352	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5698239	29164352	GHH	2	conducted the experiments|analyzed the data and wrote the manuscript	conducted the experiments	Performed the experiments	Investigation	YES
5698239	29164352	GHH	2	conducted the experiments|analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5698239	29164352	MAH	2	conducted critical reviews and helped in writing the manuscript	conducted critical reviews and helped in writing the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5698239	29164352	MC	2	conducted the experiments|analyzed the data and wrote the manuscript	conducted the experiments	Performed the experiments	Investigation	YES
5698239	29164352	MC	2	conducted the experiments|analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5698239	29164352	RK	2	conducted critical reviews and helped in writing the manuscript	conducted critical reviews and helped in writing the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5698239	29164352	SS	2	analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5698239	29164352	TS	2	designed the experiments|analyzed the data and wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5698239	29164352	TS	2	designed the experiments|analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5698239	29164352	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5698239	29164352	YK	2	assisted in conducting few experiments	assisted in conducting few experiments	Performed the experiments	Investigation	YES
4971185	27481785	All authors	2	discussed the results	discussed the results	-	-	NO
4971185	27481785	E.V.Z.	2	led sequence analyses	led sequence analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4971185	27481785	P.D.N.H.	2	provided project oversight and wrote the manuscript	provided project oversight and wrote the manuscript	Wrote the paper	Supervision|Writing - Original Draft	YES
4971185	27481785	P.J.	2	led sequence analyses	led sequence analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4971185	27481785	S.P.	2	led sequence analyses	led sequence analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270733	24936710	Beatriz Cancho-Grande	2	initially planned the experimental work and supervised the obtained results	initially planned the experimental work and supervised the obtained results	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Supervision	YES
6270733	24936710	Jesus Simal-Gandara	2	initially planned the experimental work and supervised the obtained results	initially planned the experimental work and supervised the obtained results	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Supervision	YES
6270733	24936710	Maria Figueiredo-Gonzalez	2	were responsible for the experimental work and the statistical treatment of the results	were responsible for the experimental work and the statistical treatment of the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270733	24936710	Noelia Briz-Cid	2	were responsible for the experimental work and the statistical treatment of the results	were responsible for the experimental work and the statistical treatment of the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270733	24936710	Raquel Rial-Otero	2	initially planned the experimental work and supervised the obtained results	initially planned the experimental work and supervised the obtained results	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Supervision	YES
6270733	24936710	all the authors	2	contributed, in the same degree, in the data interpretation and the writing of the paper	contributed, in the same degree, in the data interpretation and the writing of the paper	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
1975678	17878940	GK	PLoS5	Contributed reagents/materials/analysis tools|Contributed to preparing the manuscript|Advised on research matters|Contributed experimental information|Contributed some of the referenced literature/database information	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1975678	17878940	GK	PLoS5	Contributed reagents/materials/analysis tools|Contributed to preparing the manuscript|Advised on research matters|Contributed experimental information|Contributed some of the referenced literature/database information	Contributed to preparing the manuscript	Wrote the paper	Writing - Original Draft	YES
1975678	17878940	GK	PLoS5	Contributed reagents/materials/analysis tools|Contributed to preparing the manuscript|Advised on research matters|Contributed experimental information|Contributed some of the referenced literature/database information	Advised on research matters	-	-	NO
1975678	17878940	GK	PLoS5	Contributed reagents/materials/analysis tools|Contributed to preparing the manuscript|Advised on research matters|Contributed experimental information|Contributed some of the referenced literature/database information	Contributed experimental information	Performed the experiments	Investigation	YES
1975678	17878940	GK	PLoS5	Contributed reagents/materials/analysis tools|Contributed to preparing the manuscript|Advised on research matters|Contributed experimental information|Contributed some of the referenced literature/database information	Contributed some of the referenced literature/database information	Contributed reagents/materials/analysis tools	Resources|Software	YES
1975678	17878940	KF	PLoS5	Contributed reagents/materials/analysis tools|Helped extensively in building the web interface|Helped extensively in making the graphics able to display pseudoknots	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1975678	17878940	KF	PLoS5	Contributed reagents/materials/analysis tools|Helped extensively in building the web interface|Helped extensively in making the graphics able to display pseudoknots	Helped extensively in building the web interface	Contributed reagents/materials/analysis tools	Software	YES
1975678	17878940	KF	PLoS5	Contributed reagents/materials/analysis tools|Helped extensively in building the web interface|Helped extensively in making the graphics able to display pseudoknots	Helped extensively in making the graphics able to display pseudoknots	-	-	NO
1975678	17878940	WD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Discovered and developed the concepts of this theory|Carried out most of the literature study and analysis	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1975678	17878940	WD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Discovered and developed the concepts of this theory|Carried out most of the literature study and analysis	Performed the experiments	Performed the experiments	Investigation	YES
1975678	17878940	WD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Discovered and developed the concepts of this theory|Carried out most of the literature study and analysis	Analyzed the data	Analyzed the data	Formal analysis	YES
1975678	17878940	WD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Discovered and developed the concepts of this theory|Carried out most of the literature study and analysis	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1975678	17878940	WD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Discovered and developed the concepts of this theory|Carried out most of the literature study and analysis	Discovered and developed the concepts of this theory	Conceived and designed the experiments	Conceptualization	YES
1975678	17878940	WD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Discovered and developed the concepts of this theory|Carried out most of the literature study and analysis	Carried out most of the literature study and analysis	Performed the experiments	Investigation	YES
4416888	25933056	HTN	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416888	25933056	HTN	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416888	25933056	HTN	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416888	25933056	JF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416888	25933056	JF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416888	25933056	JF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416888	25933056	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416888	25933056	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416888	25933056	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416888	25933056	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416888	25933056	RW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416888	25933056	RW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416888	25933056	RW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416888	25933056	SH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416888	25933056	SH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416888	25933056	SH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5756397	29304727	ARS	2	contributed to the revision of the manuscript and performing some statistics	contributed to the revision of the manuscript and performing some statistics	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
5756397	29304727	AW	2	participated in the provision and preparation/editing of the data	participated in the provision and preparation/editing of the data	Wrote the paper	Writing - Review & Editing	YES
5756397	29304727	CR	2	contributed to the data analysis, conception and design of the study	contributed to the data analysis, conception and design of the study	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
5756397	29304727	DKM	2	contributed to the conception and design of the study, analyzed and interpreted the data	contributed to the conception and design of the study, analyzed and interpreted the data	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Methodology|Resources	YES
5756397	29304727	HS	2	supervised the study, substantially contributed to the conception and design of the study as well as the revision and editing of the manuscript	supervised the study, substantially contributed to the conception and design of the study as well as the revision and editing of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Supervision|Writing - Review & Editing	YES
5756397	29304727	SW	2	contributed to the conception and design of the study, participated in the provision of the data as well as reviewing and editing of the manuscript	contributed to the conception and design of the study, participated in the provision of the data as well as reviewing and editing of the manuscript	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Methodology|Resources|Writing - Review & Editing	YES
6293279	30266825	FCMB	2	helped with antibody production and purification	helped with antibody production and purification	Performed the experiments	Investigation	YES
6293279	30266825	IMM	2	also wrote the paper	also wrote the paper	Wrote the paper	Writing - Original Draft	YES
6293279	30266825	JP	2	carried out the global phosphoproteomic mass spectrometry and relevant data analysis	carried out the global phosphoproteomic mass spectrometry and relevant data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6293279	30266825	MEM	2	carried out all of the other experiments in this study	carried out all of the other experiments in this study	Performed the experiments	Investigation	YES
6293279	30266825	MG	2	helped with analysis of the activity of cdkl1-4	helped with analysis of the activity of cdkl1-4	-	-	NO
6293279	30266825	MT	2	carried out the global phosphoproteomic mass spectrometry and relevant data analysis|also wrote the paper	carried out the global phosphoproteomic mass spectrometry and relevant data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6293279	30266825	MT	2	carried out the global phosphoproteomic mass spectrometry and relevant data analysis|also wrote the paper	also wrote the paper	Wrote the paper	Writing - Original Draft	YES
6293279	30266825	RT	2	cloned all of the dna constructs used in this study	cloned all of the dna constructs used in this study	Performed the experiments	Investigation	YES
6293279	30266825	TM	2	cloned all of the dna constructs used in this study	cloned all of the dna constructs used in this study	Performed the experiments	Investigation	YES
5808342	29467786	CL	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5808342	29467786	FY	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5808342	29467786	HJ	PLoS52	performed the experiments|analyzed the data|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5808342	29467786	HJ	PLoS52	performed the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5808342	29467786	HJ	PLoS52	performed the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5808342	29467786	JD	PLoS52	designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5808342	29467786	JD	PLoS52	designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5808342	29467786	JD	PLoS52	designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5808342	29467786	JD	PLoS52	designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5808342	29467786	JL	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5808342	29467786	JS	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5808342	29467786	KS	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5808342	29467786	LF	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5808342	29467786	LY	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5808342	29467786	MS	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5808342	29467786	QC	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5808342	29467786	SY	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5808342	29467786	TY	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5808342	29467786	WL	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5808342	29467786	WY	PLoS52	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5808342	29467786	XS	PLoS52	performed the experiments|analyzed the data|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5808342	29467786	XS	PLoS52	performed the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5808342	29467786	XS	PLoS52	performed the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5808342	29467786	XW	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5808342	29467786	YaL	PLoS52	performed the experiments|analyzed the data|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5808342	29467786	YaL	PLoS52	performed the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5808342	29467786	YaL	PLoS52	performed the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5808342	29467786	YiL	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5808342	29467786	ZF	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5700006	29168056	All	2	the animals were handled according to internationally accepted ethical procedures	the animals were handled according to internationally accepted ethical procedures	Performed the experiments	Investigation	YES
5700006	29168056	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5700006	29168056	BL	2	interpreted data and carried out analysis	interpreted data and carried out analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5700006	29168056	LG	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5700006	29168056	MZ	2	prepared manuscript	prepared manuscript	Wrote the paper	Writing - Original Draft	YES
5700006	29168056	SZ	2	prepared manuscript	prepared manuscript	Wrote the paper	Writing - Original Draft	YES
5700006	29168056	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5700006	29168056	XL	2	interpreted data and carried out analysis	interpreted data and carried out analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5700006	29168056	ZC	2	interpreted data and carried out analysis	interpreted data and carried out analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5700006	29168056	ZW	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
1976267	17878951	AR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1976267	17878951	AR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1976267	17878951	AR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1976267	17878951	AR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1976267	17878951	CL	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1976267	17878951	CL	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1976267	17878951	CM	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1976267	17878951	CM	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1976267	17878951	EK	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1976267	17878951	EK	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1976267	17878951	FM	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1976267	17878951	FM	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1976267	17878951	FR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1976267	17878951	FR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1976267	17878951	FR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1976267	17878951	GF	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1976267	17878951	GF	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1976267	17878951	PL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1976267	17878951	PL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1976267	17878951	PL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1976267	17878951	UR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1976267	17878951	UR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1976267	17878951	UR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5808351	29467782	MP	2	designed the research|performed data collection and analysis|interpreted the data and prepared the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
5808351	29467782	MP	2	designed the research|performed data collection and analysis|interpreted the data and prepared the manuscript	performed data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5808351	29467782	MP	2	designed the research|performed data collection and analysis|interpreted the data and prepared the manuscript	interpreted the data and prepared the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5808351	29467782	VA	2	performed data collection and analysis|interpreted the data and prepared the manuscript	performed data collection and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5808351	29467782	VA	2	performed data collection and analysis|interpreted the data and prepared the manuscript	interpreted the data and prepared the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5808351	29467782	YD	2	designed the research|interpreted the data and prepared the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
5808351	29467782	YD	2	designed the research|interpreted the data and prepared the manuscript	interpreted the data and prepared the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6270734	24451253	G.-Y.X.	PLoS52	conceived and designed the study|reviewed and edited the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6270734	24451253	G.-Y.X.	PLoS52	conceived and designed the study|reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
6270734	24451253	L.W.L.	PLoS52	performed the synthetic experiments	performed the synthetic experiments	Performed the experiments	Investigation	YES
6270734	24451253	Q.W.	PLoS52	performed hplc and analysis work	performed hplc and analysis work	Performed the experiments	Investigation	YES
6270734	24451253	X.-Y.D.	PLoS52	performed the synthetic experiments	performed the synthetic experiments	Performed the experiments	Investigation	YES
6270734	24451253	X.M.	PLoS52	conceived and designed the study|wrote the paper|reviewed and edited the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6270734	24451253	X.M.	PLoS52	conceived and designed the study|wrote the paper|reviewed and edited the manuscript	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270734	24451253	X.M.	PLoS52	conceived and designed the study|wrote the paper|reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
6270734	24451253	Z.-G.C.	PLoS52	conceived and designed the study|performed the synthetic experiments|wrote the paper	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6270734	24451253	Z.-G.C.	PLoS52	conceived and designed the study|performed the synthetic experiments|wrote the paper	performed the synthetic experiments	Performed the experiments	Investigation	YES
6270734	24451253	Z.-G.C.	PLoS52	conceived and designed the study|performed the synthetic experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416889	25933001	AET	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416889	25933001	AET	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4416889	25933001	AET	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416889	25933001	CJP	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4416889	25933001	CJP	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416889	25933001	DAE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416889	25933001	DAE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416889	25933001	DAE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416889	25933001	DAE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416889	25933001	DAE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416889	25933001	DCW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416889	25933001	DCW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416889	25933001	DCW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416889	25933001	DCW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416889	25933001	DLP	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416889	25933001	DRM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416889	25933001	DRM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416889	25933001	DRM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416889	25933001	FPZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416889	25933001	FPZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416889	25933001	FPZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416889	25933001	JEJ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5756416	29304740	AD	2	performed pacbio sequencing and assembly	performed pacbio sequencing and assembly	Performed the experiments	Investigation	YES
5756416	29304740	BHH	2	analyzed data, supervised the bioinformatics part of the project, and wrote the manuscript	analyzed data, supervised the bioinformatics part of the project, and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Supervision|Writing - Original Draft	YES
5756416	29304740	FP	2	analyzed and annotated the genome and wrote the manuscript	analyzed and annotated the genome and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5756416	29304740	MAZL	2	analyzed and annotated the genome and wrote the manuscript	analyzed and annotated the genome and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5756416	29304740	MB	2	performed biological experiments including dna isolation	performed biological experiments including dna isolation	Performed the experiments	Investigation	YES
5756416	29304740	SG	2	supervised the biological part of the project	supervised the biological part of the project	-	Supervision	YES
6293338	30446598	PKCd	2	mice and reagents, and edited manuscript	mice and reagents, and edited manuscript	Wrote the paper	Writing - Review & Editing	YES
6293338	30446598	RNK	2	edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
6293338	30446598	SS	2	helped with seahorse experiments	helped with seahorse experiments	Performed the experiments	Investigation	YES
6293338	30446598	TT	2	helped with seahorse experiments	helped with seahorse experiments	Performed the experiments	Investigation	YES
6293338	30446598	YCJ	2	helped with seahorse experiments	helped with seahorse experiments	Performed the experiments	Investigation	YES
5700909	29170893	HTY	PLoS5	Performed the experiments|Contributed materials	Performed the experiments	Performed the experiments	Investigation	YES
5700909	29170893	HTY	PLoS5	Performed the experiments|Contributed materials	Contributed materials	Contributed reagents/materials/analysis tools	Resources	YES
5700909	29170893	JPG	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5700909	29170893	LMF	PLoS5	Conceived and designed the experiments|Contributed materials	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5700909	29170893	LMF	PLoS5	Conceived and designed the experiments|Contributed materials	Contributed materials	Contributed reagents/materials/analysis tools	Resources	YES
5700909	29170893	SYH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5700909	29170893	TMW	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5700909	29170893	TMW	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5700909	29170893	YG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the date|Contributed materials|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5700909	29170893	YG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the date|Contributed materials|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
5700909	29170893	YG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the date|Contributed materials|Wrote the paper	Analyzed the date	Analyzed the data	Formal analysis	YES
5700909	29170893	YG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the date|Contributed materials|Wrote the paper	Contributed materials	Contributed reagents/materials/analysis tools	Resources	YES
5700909	29170893	YG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the date|Contributed materials|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1976389	17878955	AM	PLoS5	Analyzed the data|Made the crystal structure analyses	Analyzed the data	Analyzed the data	Formal analysis	YES
1976389	17878955	AM	PLoS5	Analyzed the data|Made the crystal structure analyses	Made the crystal structure analyses	Analyzed the data	Formal analysis	YES
1976389	17878955	CK	PLoS5	Analyzed the data|Performed the bio-informatic analyses	Analyzed the data	Analyzed the data	Formal analysis	YES
1976389	17878955	CK	PLoS5	Analyzed the data|Performed the bio-informatic analyses	Performed the bio-informatic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
1976389	17878955	JB	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416890	25933433	CSH	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416890	25933433	HYS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416890	25933433	HYS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416890	25933433	HYS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416890	25933433	HYS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416890	25933433	JYY	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416890	25933433	JYY	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416890	25933433	JYY	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416890	25933433	NK	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416890	25933433	NK	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
6270735	25230121	Barbora Orlikova	2	contributed interpretation of the data	contributed interpretation of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6270735	25230121	Chee-Yan Choo	2	planned and supervised the work and drafted and edited the paper	planned and supervised the work and drafted and edited the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
6270735	25230121	Marc Diederich	2	planned and supervised the work and drafted and edited the paper	planned and supervised the work and drafted and edited the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
6270735	25230121	Marc Schumacher	2	realized the experimental work	realized the experimental work	Performed the experiments	Investigation	YES
6270735	25230121	Marie-Helene Teiten	2	contributed interpretation of the data	contributed interpretation of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6270735	25230121	Mario Dicato	2	planned and supervised the work and drafted and edited the paper	planned and supervised the work and drafted and edited the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
6270735	25230121	Sebastien Chateauvieux	2	contributed interpretation of the data	contributed interpretation of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6270735	25230121	Sheherazade Hajjouli	2	realized the experimental work	realized the experimental work	Performed the experiments	Investigation	YES
4971187	27481787	D.M.	2	conceived, wrote and revised the manuscript	conceived, wrote and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
4971187	27481787	D.P.	2	conceived, wrote and revised the manuscript	conceived, wrote and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
5756429	29304736	CDT	1	Analysis of all results|Manuscript writing and figures	Analysis of all results	Analyzed the data	Formal analysis	YES
5756429	29304736	CDT	1	Analysis of all results|Manuscript writing and figures	Manuscript writing and figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5756429	29304736	NN	1	Research experimentation	Research experimentation	Performed the experiments	Investigation	YES
5756429	29304736	PCBS	1	Experimental concept and design|Analysis of all results|Manuscript writing and figures	Experimental concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5756429	29304736	PCBS	1	Experimental concept and design|Analysis of all results|Manuscript writing and figures	Analysis of all results	Analyzed the data	Formal analysis	YES
5756429	29304736	PCBS	1	Experimental concept and design|Analysis of all results|Manuscript writing and figures	Manuscript writing and figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5756429	29304736	SI	1	Research experimentation|Analysis of all results|Manuscript writing and figures	Research experimentation	Performed the experiments	Investigation	YES
5756429	29304736	SI	1	Research experimentation|Analysis of all results|Manuscript writing and figures	Analysis of all results	Analyzed the data	Formal analysis	YES
5756429	29304736	SI	1	Research experimentation|Analysis of all results|Manuscript writing and figures	Manuscript writing and figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5756429	29304736	YW	1	Experimental concept and design|Analysis of all results|Manuscript writing and figures	Experimental concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5756429	29304736	YW	1	Experimental concept and design|Analysis of all results|Manuscript writing and figures	Analysis of all results	Analyzed the data	Formal analysis	YES
5756429	29304736	YW	1	Experimental concept and design|Analysis of all results|Manuscript writing and figures	Manuscript writing and figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5701898	29177886	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5701898	29177886	BZ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5701898	29177886	GC	PLoS52	conceived and designed the study|analyzed the data|reviewed and edited the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5701898	29177886	GC	PLoS52	conceived and designed the study|analyzed the data|reviewed and edited the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5701898	29177886	GC	PLoS52	conceived and designed the study|analyzed the data|reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5701898	29177886	JW	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5701898	29177886	MD	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5701898	29177886	The authors	PLoS52	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5701898	29177886	WZ	PLoS52	conceived and designed the study|performed the experiments|analyzed the data|wrote the paper	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5701898	29177886	WZ	PLoS52	conceived and designed the study|performed the experiments|analyzed the data|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5701898	29177886	WZ	PLoS52	conceived and designed the study|performed the experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5701898	29177886	WZ	PLoS52	conceived and designed the study|performed the experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5701898	29177886	YG	PLoS52	performed the experiments|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5701898	29177886	YG	PLoS52	performed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5701898	29177886	YW	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5701898	29177886	ZC	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5701898	29177886	ZL	PLoS52	conceived and designed the study|reviewed and edited the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5701898	29177886	ZL	PLoS52	conceived and designed the study|reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5808591	29467775	BY	2	helped with the experiment and raised many good questions and solutions to the present work	helped with the experiment and raised many good questions and solutions to the present work	Performed the experiments	Investigation	YES
5808591	29467775	J-GH	2	the first authors director, funded the first author to conduct this study and gave many constructive suggestions for the writing work	the first authors director, funded the first author to conduct this study and gave many constructive suggestions for the writing work	Performed the experiments|Wrote the paper	Funding acquisition|Investigation	YES
5808591	29467775	QY	2	provided some useful and supportive data and gave many good advices to this work	provided some useful and supportive data and gave many good advices to this work	Contributed reagents/materials/analysis tools	Resources	YES
5808591	29467775	SJ	2	helped with the experiment and raised many good questions and solutions to the present work	helped with the experiment and raised many good questions and solutions to the present work	Performed the experiments	Investigation	YES
5808591	29467775	SR	2	helped the first author with the data analysis and gave many constructive suggestions for the analysis and writing work	helped the first author with the data analysis and gave many constructive suggestions for the analysis and writing work	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation	YES
5808591	29467775	SZ	2	did the main experiments, obtained the whole dataset and wrote the whole manuscript	did the main experiments, obtained the whole dataset and wrote the whole manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5808591	29467775	WZ	2	provided some useful and supportive data and gave many good advices to this work	provided some useful and supportive data and gave many good advices to this work	Contributed reagents/materials/analysis tools	Resources	YES
6315289	30257965	BDS	2	provided experimental support	provided experimental support	-	-	NO
6315289	30257965	CM	2	performed the gplvm analysis	performed the gplvm analysis	Performed the experiments	Investigation	YES
6315289	30257965	EA	2	built the sted microscope and helped with super-resolution imaging	built the sted microscope and helped with super-resolution imaging	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
6315289	30257965	FB	2	performed the gplvm analysis	performed the gplvm analysis	Performed the experiments	Investigation	YES
6315289	30257965	FT	2	performed the gplvm analysis	performed the gplvm analysis	Performed the experiments	Investigation	YES
6315289	30257965	JR	2	performed pseudotime, statistical and binding site analyses	performed pseudotime, statistical and binding site analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6315289	30257965	JT	2	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
6315289	30257965	LW	2	performed pseudotime, statistical and binding site analyses	performed pseudotime, statistical and binding site analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6315289	30257965	MAS	2	supervised the study	supervised the study	-	Supervision	YES
6315289	30257965	WHG	2	performed western blot and chip-qpcr analyses, qrt pcr, data analysis and graphical representations of the experimental results	performed western blot and chip-qpcr analyses, qrt pcr, data analysis and graphical representations of the experimental results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4416891	25933215	BYL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416891	25933215	BYL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416891	25933215	BYL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416891	25933215	BYL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416891	25933215	BYL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416891	25933215	DN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416891	25933215	DN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416891	25933215	DN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416891	25933215	DN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416891	25933215	ELT	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416891	25933215	ELT	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416891	25933215	ELT	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416891	25933215	LZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416891	25933215	LZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416891	25933215	LZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416891	25933215	LZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416891	25933215	LZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416891	25933215	SLL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416891	25933215	SLL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416891	25933215	SLL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416891	25933215	SPC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416891	25933215	SPC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416891	25933215	SPC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416891	25933215	TFW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416891	25933215	TFW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416891	25933215	TFW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270736	25000466	ESI-MS	PLoS52	determined stability	determined stability	-	-	NO
6270736	25000466	H. Miyazawa	PLoS52	contributed in the preparing of the manuscript	contributed in the preparing of the manuscript	Wrote the paper	Writing - Original Draft	YES
6270736	25000466	K. Kino	PLoS52	designed research|analyzed the data|contributed in the preparing of the manuscript	designed research	Conceived and designed the experiments	Methodology	YES
6270736	25000466	K. Kino	PLoS52	designed research|analyzed the data|contributed in the preparing of the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
6270736	25000466	K. Kino	PLoS52	designed research|analyzed the data|contributed in the preparing of the manuscript	contributed in the preparing of the manuscript	Wrote the paper	Writing - Original Draft	YES
6270736	25000466	M. Morikawa	PLoS52	analyzed the data|contributed in the preparing of the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
6270736	25000466	M. Morikawa	PLoS52	analyzed the data|contributed in the preparing of the manuscript	contributed in the preparing of the manuscript	Wrote the paper	Writing - Original Draft	YES
6270736	25000466	M. Suzuki	PLoS52	contributed with valuable discussions and scientific input	contributed with valuable discussions and scientific input	-	-	NO
6270736	25000466	T. Kobayashi	PLoS52	contributed with valuable discussions and scientific input	contributed with valuable discussions and scientific input	-	-	NO
6270736	25000466	T. Senda	PLoS52	analyzed the data|performed synthesis, purification and time course analysis	analyzed the data	Analyzed the data	Formal analysis	YES
6270736	25000466	T. Senda	PLoS52	analyzed the data|performed synthesis, purification and time course analysis	performed synthesis, purification and time course analysis	Performed the experiments	Investigation	YES
5756433	29304739	ASNR	2	helped ab with	helped ab with	-	-	NO
5702286	29178045	All authors	2	contributed equally in writing this review article|read and approved the final manuscript|thank their universities for their help in accomplishing this work	contributed equally in writing this review article	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5702286	29178045	All authors	2	contributed equally in writing this review article|read and approved the final manuscript|thank their universities for their help in accomplishing this work	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5702286	29178045	All authors	2	contributed equally in writing this review article|read and approved the final manuscript|thank their universities for their help in accomplishing this work	thank their universities for their help in accomplishing this work	-	-	NO
5702286	29178045	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
1976391	17878954	BB	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1976391	17878954	BB	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1976391	17878954	DS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1976391	17878954	DS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1976391	17878954	DS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1976391	17878954	EM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Enrolled patients	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1976391	17878954	EM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Enrolled patients	Analyzed the data	Analyzed the data	Formal analysis	YES
1976391	17878954	EM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Enrolled patients	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1976391	17878954	EM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Enrolled patients	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1976391	17878954	EM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Enrolled patients	Enrolled patients	Performed the experiments	Investigation	YES
1976391	17878954	GG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1976391	17878954	GG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1976391	17878954	GG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1976391	17878954	GG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1976391	17878954	JB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1976391	17878954	JB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1976391	17878954	JB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1976391	17878954	KC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1976391	17878954	KC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1976391	17878954	KC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1976391	17878954	KC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1976391	17878954	KC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1976391	17878954	OS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1976391	17878954	OS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1976391	17878954	OS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1976391	17878954	OS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1976391	17878954	OS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1976391	17878954	QZ	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1976391	17878954	QZ	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5809434	29472944	All authors	2	listed have made a substantial, direct and intellectual contribution to the work, and approved it for publication	listed have made a substantial, direct and intellectual contribution to the work, and approved it for publication	-	-	NO
4971188	27481788	All	2	gave final approval for publication	gave final approval for publication	-	-	NO
4971188	27481788	B.T.M.D.	2	drafted the manuscript|provided data for the figures	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4971188	27481788	B.T.M.D.	2	drafted the manuscript|provided data for the figures	provided data for the figures	Contributed reagents/materials/analysis tools	Resources|Visualization	YES
4971188	27481788	C.L.S.	2	drafted the manuscript|provided data for the figures	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4971188	27481788	C.L.S.	2	drafted the manuscript|provided data for the figures	provided data for the figures	Contributed reagents/materials/analysis tools	Resources|Visualization	YES
4971188	27481788	R.Y.	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
3203473	22073374	AML	2	results analysis and interpretation|research theme defining, methods designing and manuscript writing	results analysis and interpretation	Analyzed the data	Formal analysis	YES
3203473	22073374	AML	2	results analysis and interpretation|research theme defining, methods designing and manuscript writing	research theme defining, methods designing and manuscript writing	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Writing - Original Draft	YES
3203473	22073374	DC	2	laboratory experiments performing	laboratory experiments performing	Performed the experiments	Investigation	YES
3203473	22073374	FF	2	laboratory experiments performing	laboratory experiments performing	Performed the experiments	Investigation	YES
3203473	22073374	IT	2	laboratory experiments performing	laboratory experiments performing	Performed the experiments	Investigation	YES
3203473	22073374	JJP	2	research theme defining, methods designing and manuscript writing	research theme defining, methods designing and manuscript writing	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Writing - Original Draft	YES
3203473	22073374	SM	2	results analysis and interpretation|research theme defining, methods designing and manuscript writing	results analysis and interpretation	Analyzed the data	Formal analysis	YES
3203473	22073374	SM	2	results analysis and interpretation|research theme defining, methods designing and manuscript writing	research theme defining, methods designing and manuscript writing	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Writing - Original Draft	YES
3203473	22073374	VL	2	laboratory experiments performing|results analysis and interpretation|research theme defining, methods designing and manuscript writing	laboratory experiments performing	Performed the experiments	Investigation	YES
3203473	22073374	VL	2	laboratory experiments performing|results analysis and interpretation|research theme defining, methods designing and manuscript writing	results analysis and interpretation	Analyzed the data	Formal analysis	YES
3203473	22073374	VL	2	laboratory experiments performing|results analysis and interpretation|research theme defining, methods designing and manuscript writing	research theme defining, methods designing and manuscript writing	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Writing - Original Draft	YES
4416892	25933137	BI	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Revised the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4416892	25933137	BI	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Revised the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416892	25933137	BI	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Revised the manuscript	Revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4416892	25933137	GL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Revised the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4416892	25933137	GL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Revised the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4416892	25933137	GL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Revised the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416892	25933137	GL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Revised the manuscript	Revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4416892	25933137	GS	PLoS5	Contributed reagents/materials/analysis tools|Revised the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416892	25933137	GS	PLoS5	Contributed reagents/materials/analysis tools|Revised the manuscript	Revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4416892	25933137	HCS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Revised the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4416892	25933137	HCS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Revised the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416892	25933137	HCS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Revised the manuscript	Revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4416892	25933137	HK	PLoS5	Contributed reagents/materials/analysis tools|Revised the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416892	25933137	HK	PLoS5	Contributed reagents/materials/analysis tools|Revised the manuscript	Revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4416892	25933137	JS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416892	25933137	JS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416892	25933137	JS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416892	25933137	JS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416892	25933137	JW	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Revised the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4416892	25933137	JW	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Revised the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416892	25933137	JW	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Revised the manuscript	Revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4416892	25933137	MKK	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416892	25933137	MKK	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416892	25933137	MKK	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416892	25933137	MR	PLoS5	Contributed reagents/materials/analysis tools|Revised the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416892	25933137	MR	PLoS5	Contributed reagents/materials/analysis tools|Revised the manuscript	Revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4416892	25933137	RBD	PLoS5	Contributed reagents/materials/analysis tools|Revised the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416892	25933137	RBD	PLoS5	Contributed reagents/materials/analysis tools|Revised the manuscript	Revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4416892	25933137	RZ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Revised the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4416892	25933137	RZ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Revised the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4416892	25933137	RZ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Revised the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416892	25933137	RZ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Revised the manuscript	Revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4416892	25933137	TAS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Revised the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416892	25933137	TAS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Revised the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4416892	25933137	TAS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Revised the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416892	25933137	TAS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Revised the manuscript	Revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4416892	25933137	TEL	PLoS5	Performed the experiments|Analyzed the data|Revised the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4416892	25933137	TEL	PLoS5	Performed the experiments|Analyzed the data|Revised the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4416892	25933137	TEL	PLoS5	Performed the experiments|Analyzed the data|Revised the manuscript	Revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4416892	25933137	UK	PLoS5	Contributed reagents/materials/analysis tools|Revised the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416892	25933137	UK	PLoS5	Contributed reagents/materials/analysis tools|Revised the manuscript	Revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
6375364	30842867	F.F.	2	synthesized the complex and performed the chemical analysis	synthesized the complex and performed the chemical analysis	Performed the experiments	Investigation	YES
6375364	30842867	H.T.	2	synthesized the complex and performed the chemical analysis	synthesized the complex and performed the chemical analysis	Performed the experiments	Investigation	YES
6375364	30842867	J.N.	2	performed the ab initio calculations	performed the ab initio calculations	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6375364	30842867	L.C.	2	performed the ab initio calculations	performed the ab initio calculations	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6375364	30842867	L.U.	2	performed the ab initio calculations	performed the ab initio calculations	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6375364	30842867	L.Z.	2	performed the x-ray powder measurements	performed the x-ray powder measurements	Performed the experiments	Investigation	YES
6375364	30842867	M.G.	2	performed the ab initio calculations|performed the luminescence measurements	performed the ab initio calculations	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6375364	30842867	M.G.	2	performed the ab initio calculations|performed the luminescence measurements	performed the luminescence measurements	Performed the experiments	Investigation	YES
6375364	30842867	M.H.	2	performed the fir measurements	performed the fir measurements	Performed the experiments	Investigation	YES
6375364	30842867	M.O.	2	performed the fir measurements	performed the fir measurements	Performed the experiments	Investigation	YES
6375364	30842867	P.Z.	2	synthesized the complex and performed the chemical analysis	synthesized the complex and performed the chemical analysis	Performed the experiments	Investigation	YES
6375364	30842867	S.P.	2	performed the luminescence measurements	performed the luminescence measurements	Performed the experiments	Investigation	YES
6375364	30842867	T.B.N.	2	performed the luminescence measurements	performed the luminescence measurements	Performed the experiments	Investigation	YES
6375364	30842867	T.S.	2	performed the x-ray powder measurements	performed the x-ray powder measurements	Performed the experiments	Investigation	YES
6375364	30842867	W.F.	2	solved the structure	solved the structure	-	-	NO
6316172	30482756	AS	2	designed the study and wrote the paper|supervised the study	designed the study and wrote the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
6316172	30482756	AS	2	designed the study and wrote the paper|supervised the study	supervised the study	-	Supervision	YES
6316172	30482756	EC	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
6316172	30482756	GM	2	carried out the experiments|analysed computational predictions and experimental data|designed the study and wrote the paper|supervised the study	carried out the experiments	Performed the experiments	Investigation	YES
6316172	30482756	GM	2	carried out the experiments|analysed computational predictions and experimental data|designed the study and wrote the paper|supervised the study	analysed computational predictions and experimental data	Analyzed the data	Formal analysis	YES
6316172	30482756	GM	2	carried out the experiments|analysed computational predictions and experimental data|designed the study and wrote the paper|supervised the study	designed the study and wrote the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
6316172	30482756	GM	2	carried out the experiments|analysed computational predictions and experimental data|designed the study and wrote the paper|supervised the study	supervised the study	-	Supervision	YES
6316172	30482756	MAL	2	carried out the experiments|analysed computational predictions and experimental data|designed the study and wrote the paper	carried out the experiments	Performed the experiments	Investigation	YES
6316172	30482756	MAL	2	carried out the experiments|analysed computational predictions and experimental data|designed the study and wrote the paper	analysed computational predictions and experimental data	Analyzed the data	Formal analysis	YES
6316172	30482756	MAL	2	carried out the experiments|analysed computational predictions and experimental data|designed the study and wrote the paper	designed the study and wrote the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
6316172	30482756	S-JD	2	carried out the computational modelling|analysed computational predictions and experimental data|designed the study and wrote the paper	carried out the computational modelling	Performed the experiments	Formal analysis|Investigation|Methodology	YES
6316172	30482756	S-JD	2	carried out the computational modelling|analysed computational predictions and experimental data|designed the study and wrote the paper	analysed computational predictions and experimental data	Analyzed the data	Formal analysis	YES
6316172	30482756	S-JD	2	carried out the computational modelling|analysed computational predictions and experimental data|designed the study and wrote the paper	designed the study and wrote the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5756445	29306330	AS	2	carried out the experiment and data analysis	carried out the experiment and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5756445	29306330	JL	2	carried out the experiment and data analysis|wrote the manuscript	carried out the experiment and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5756445	29306330	JL	2	carried out the experiment and data analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5756445	29306330	MJN	2	carried out the experiment and data analysis	carried out the experiment and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5756445	29306330	QY	2	wrote the manuscript|designed the experiment, and coordinated and organized all research activities	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5756445	29306330	QY	2	wrote the manuscript|designed the experiment, and coordinated and organized all research activities	designed the experiment, and coordinated and organized all research activities	Conceived and designed the experiments	Methodology|Project administration	YES
5756445	29306330	RM	2	designed the experiment, and coordinated and organized all research activities	designed the experiment, and coordinated and organized all research activities	Conceived and designed the experiments	Methodology|Project administration	YES
5756445	29306330	RS	2	carried out the experiment and data analysis	carried out the experiment and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
1976392	17878950	AF	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1976392	17878950	AF	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1976392	17878950	MA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1976392	17878950	MA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1976392	17878950	MA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1976392	17878950	MA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1976392	17878950	MA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1976392	17878950	MU	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1976392	17878950	NP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1976392	17878950	NP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1976392	17878950	NP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1976392	17878950	NP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1976392	17878950	PN	PLoS5	Akhras	Akhras	-	-	NO
1976392	17878950	RW	PLoS5	Center	Center	-	-	NO
1976392	17878950	ST	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5704030	29181600	ABA	2	guided the study design	guided the study design	Conceived and designed the experiments	Methodology|Supervision	YES
5704030	29181600	All	2	the data are presented in the main paper	the data are presented in the main paper	-	-	NO
5704030	29181600	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5704030	29181600	HW	2	guided the study design	guided the study design	Conceived and designed the experiments	Methodology|Supervision	YES
5704030	29181600	MH	2	designed the study, analysed and interpreted the data, and revised the manuscript	designed the study, analysed and interpreted the data, and revised the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
5704030	29181600	MO	2	conducted the study, collected the data, analysed and interpreted the data, and wrote the manuscript	conducted the study, collected the data, analysed and interpreted the data, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5704030	29181600	MRK	2	guided the study design	guided the study design	Conceived and designed the experiments	Methodology|Supervision	YES
5704030	29181600	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
3203474	22073368	AH	PLoS52	experiments design, manuscript writing	experiments design, manuscript writing	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3203474	22073368	AX	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
3203474	22073368	CAP	PLoS52	experiments design, manuscript writing	experiments design, manuscript writing	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3203474	22073368	ENS	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
3203474	22073368	GT	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
3203474	22073368	MGA	PLoS52	experiments design, manuscript writing	experiments design, manuscript writing	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3203474	22073368	MK	PLoS52	experiments design, manuscript writing	experiments design, manuscript writing	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3203474	22073368	TA	PLoS52	reformed statistical analysis	reformed statistical analysis	Analyzed the data	Formal analysis	YES
3203474	22073368	VK	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5809493	29472939	BC	7	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5809493	29472939	FT	7	Completed the field work|Wrote the paper	Completed the field work	Performed the experiments	Investigation	YES
5809493	29472939	FT	7	Completed the field work|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5809493	29472939	SL	7	Designed the research|Analyzed the data	Designed the research	Conceived and designed the experiments	Methodology	YES
5809493	29472939	SL	7	Designed the research|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5809493	29472939	YK	7	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5809493	29472939	YK	7	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5809493	29472939	YX	7	Designed the research|Completed the field work|Analyzed the data|Wrote the paper	Designed the research	Conceived and designed the experiments	Methodology	YES
5809493	29472939	YX	7	Designed the research|Completed the field work|Analyzed the data|Wrote the paper	Completed the field work	Performed the experiments	Investigation	YES
5809493	29472939	YX	7	Designed the research|Completed the field work|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5809493	29472939	YX	7	Designed the research|Completed the field work|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4971189	27481789	All authors	2	contributed substantially to the conception and design of this article, drafting the article and revising it critically for important intellectual content and the final approval of the version to be published	contributed substantially to the conception and design of this article, drafting the article and revising it critically for important intellectual content and the final approval of the version to be published	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
4416893	25933414	AV	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416893	25933414	AV	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416893	25933414	AV	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416893	25933414	CDO	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416893	25933414	CDO	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416893	25933414	CDO	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416893	25933414	CDO	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416893	25933414	CEW	PLoS5	Conceived and designed the experiments|Contributed to the overall revision of this manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416893	25933414	CEW	PLoS5	Conceived and designed the experiments|Contributed to the overall revision of this manuscript	Contributed to the overall revision of this manuscript	Wrote the paper	Writing - Review & Editing	YES
4416893	25933414	CMI	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Contributed to the overall revision of this manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4416893	25933414	CMI	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Contributed to the overall revision of this manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416893	25933414	CMI	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Contributed to the overall revision of this manuscript	Contributed to the overall revision of this manuscript	Wrote the paper	Writing - Review & Editing	YES
4416893	25933414	CW	PLoS5	Conceived and designed the experiments|Contributed to the overall revision of this manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416893	25933414	CW	PLoS5	Conceived and designed the experiments|Contributed to the overall revision of this manuscript	Contributed to the overall revision of this manuscript	Wrote the paper	Writing - Review & Editing	YES
4416893	25933414	EM	PLoS5	Implementation of the study|Contributed to the overall revision of this manuscript	Implementation of the study	Performed the experiments	Investigation	YES
4416893	25933414	EM	PLoS5	Implementation of the study|Contributed to the overall revision of this manuscript	Contributed to the overall revision of this manuscript	Wrote the paper	Writing - Review & Editing	YES
4416893	25933414	FTP	PLoS5	Contributed reagents/materials/analysis tools|Contributed to the overall revision of this manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416893	25933414	FTP	PLoS5	Contributed reagents/materials/analysis tools|Contributed to the overall revision of this manuscript	Contributed to the overall revision of this manuscript	Wrote the paper	Writing - Review & Editing	YES
4416893	25933414	LG	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416893	25933414	SM	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416893	25933414	SS	PLoS5	Performed the experiments|Contributed to the overall revision of this manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4416893	25933414	SS	PLoS5	Performed the experiments|Contributed to the overall revision of this manuscript	Contributed to the overall revision of this manuscript	Wrote the paper	Writing - Review & Editing	YES
4416893	25933414	VD	PLoS5	Performed the experiments|Contributed to the overall revision of this manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4416893	25933414	VD	PLoS5	Performed the experiments|Contributed to the overall revision of this manuscript	Contributed to the overall revision of this manuscript	Wrote the paper	Writing - Review & Editing	YES
4416893	25933414	ZN	PLoS5	Implementation of the study|Contributed to the overall revision of this manuscript	Implementation of the study	Performed the experiments	Investigation	YES
4416893	25933414	ZN	PLoS5	Implementation of the study|Contributed to the overall revision of this manuscript	Contributed to the overall revision of this manuscript	Wrote the paper	Writing - Review & Editing	YES
6270738	25302702	H.L.	2	were involved in manuscript preparation	were involved in manuscript preparation	Wrote the paper	Writing - Original Draft	YES
6270738	25302702	N.X.	2	were involved in manuscript preparation	were involved in manuscript preparation	Wrote the paper	Writing - Original Draft	YES
6270738	25302702	U.F.	2	critically reviewed the manuscript	critically reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
1976393	17878935	GJ	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1976393	17878935	GL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1976393	17878935	GL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1976393	17878935	GL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1976393	17878935	JW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1976393	17878935	SR	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1976393	17878935	SR	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1976393	17878935	SZ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1976393	17878935	SZ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5759201	29310587	AN	2	executed the experiments, aided in experimental design and data interpretation, and were involved in drafting of the manuscript	executed the experiments, aided in experimental design and data interpretation, and were involved in drafting of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5759201	29310587	ART	2	were both substantially involved in experimental design, data interpretation, and writing the manuscript	were both substantially involved in experimental design, data interpretation, and writing the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5759201	29310587	HAC	2	executed the experiments, aided in experimental design and data interpretation, and were involved in drafting of the manuscript	executed the experiments, aided in experimental design and data interpretation, and were involved in drafting of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5759201	29310587	KG	2	was involved in the analysis, interpretation of the results, and assisted in writing the manuscript	was involved in the analysis, interpretation of the results, and assisted in writing the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5759201	29310587	KL	2	performed the data analysis and edited the manuscript	performed the data analysis and edited the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5759201	29310587	LEM	2	were both substantially involved in experimental design, data interpretation, and writing the manuscript	were both substantially involved in experimental design, data interpretation, and writing the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5759201	29310587	MDD	2	aided in data analysis design, execution, and interpretation	aided in data analysis design, execution, and interpretation	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5759201	29310587	MKS	2	executed the experiments, aided in experimental design and data interpretation, and were involved in drafting of the manuscript	executed the experiments, aided in experimental design and data interpretation, and were involved in drafting of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5759201	29310587	ML	2	led experimental design, executed the experiments, and interpretation	led experimental design, executed the experiments, and interpretation	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5759201	29310587	MM	2	was involved in critically revising the manuscript	was involved in critically revising the manuscript	Wrote the paper	Writing - Review & Editing	YES
5759201	29310587	MSM	2	performed the data analysis and edited the manuscript	performed the data analysis and edited the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5759201	29310587	RTB	2	analyzed the data and aided in writing the manuscript	analyzed the data and aided in writing the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5759201	29310587	UMI	2	consensus analysis	consensus analysis	-	-	NO
6331720	30498131	AK	2	evaluated the pathology of the kidneys	evaluated the pathology of the kidneys	Performed the experiments	Investigation	YES
6331720	30498131	BrdU	2	incorporation, and cell injection experiments	incorporation, and cell injection experiments	Performed the experiments	Investigation	YES
6331720	30498131	HT	2	generated the gro-seq data	generated the gro-seq data	Performed the experiments	Investigation	YES
6331720	30498131	MB	2	planned the project and wrote the manuscript	planned the project and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
6331720	30498131	MCIK	2	provided advice for analysis of the autoimmune phenotype	provided advice for analysis of the autoimmune phenotype	Performed the experiments	Investigation	YES
6331720	30498131	MF	2	performed the bioinformatic analysis of all rna seq and chip-seq data, respectively	performed the bioinformatic analysis of all rna seq and chip-seq data, respectively	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6331720	30498131	MJ	2	performed the bioinformatic analysis of all rna seq and chip-seq data, respectively	performed the bioinformatic analysis of all rna seq and chip-seq data, respectively	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6331720	30498131	PB	2	performed most experiments|planned the project and wrote the manuscript	performed most experiments	Performed the experiments	Investigation	YES
6331720	30498131	PB	2	performed most experiments|planned the project and wrote the manuscript	planned the project and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
6331720	30498131	SSB	2	antibody titers	antibody titers	Performed the experiments	Investigation	YES
3203475	22073371	CLPL	2	laboratory experiments performing	laboratory experiments performing	Performed the experiments	Investigation	YES
3203475	22073371	CTFO	2	laboratory experiments performing	laboratory experiments performing	Performed the experiments	Investigation	YES
3203475	22073371	FRL	2	research theme defining, methods designing and manuscript writing	research theme defining, methods designing and manuscript writing	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Writing - Original Draft	YES
3203475	22073371	JFR-V	2	results analysis and interpretation	results analysis and interpretation	Analyzed the data	Formal analysis	YES
3203475	22073371	JRM-V	2	results analysis and interpretation	results analysis and interpretation	Analyzed the data	Formal analysis	YES
3203475	22073371	LGA	2	research theme defining, methods designing and manuscript writing	research theme defining, methods designing and manuscript writing	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Writing - Original Draft	YES
3203475	22073371	LOCM	2	laboratory experiments performing|results analysis and interpretation|research theme defining, methods designing and manuscript writing	laboratory experiments performing	Performed the experiments	Investigation	YES
3203475	22073371	LOCM	2	laboratory experiments performing|results analysis and interpretation|research theme defining, methods designing and manuscript writing	results analysis and interpretation	Analyzed the data	Formal analysis	YES
3203475	22073371	LOCM	2	laboratory experiments performing|results analysis and interpretation|research theme defining, methods designing and manuscript writing	research theme defining, methods designing and manuscript writing	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Writing - Original Draft	YES
3203475	22073371	SRM	2	research theme defining, methods designing and manuscript writing	research theme defining, methods designing and manuscript writing	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Writing - Original Draft	YES
3203475	22073371	TSG	2	laboratory experiments performing	laboratory experiments performing	Performed the experiments	Investigation	YES
5809497	29472942	All authors	2	listed have made a substantial, direct and intellectual contribution to the work, and approved it for publication	listed have made a substantial, direct and intellectual contribution to the work, and approved it for publication	-	-	NO
4637055	26581164	Joshua Sikhu Okonya	2	designed the study, collected and analyzed data, and drafted the paper	designed the study, collected and analyzed data, and drafted the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4637055	26581164	Jurgen Kroschel	2	conceived, designed, and supervised all stages of the study	conceived, designed, and supervised all stages of the study	Conceived and designed the experiments	Conceptualization|Methodology|Supervision	YES
4971190	27481790	All authors	2	contributed to the development of ideas and information in this paper	contributed to the development of ideas and information in this paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5716961	29210028	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5716961	29210028	HJ	PLoS52	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5716961	29210028	JP	PLoS52	carried out the experiments|wrote the paper|obtained the funding	carried out the experiments	Performed the experiments	Investigation	YES
5716961	29210028	JP	PLoS52	carried out the experiments|wrote the paper|obtained the funding	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5716961	29210028	JP	PLoS52	carried out the experiments|wrote the paper|obtained the funding	obtained the funding	-	Funding acquisition	YES
5716961	29210028	WJ	PLoS52	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5716961	29210028	XL	PLoS52	designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
5716961	29210028	YT	PLoS52	wrote the paper|designed the research	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5716961	29210028	YT	PLoS52	wrote the paper|designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
6270739	25517346	A.A.C.A.	7	analysis and interpretation, data collection, figures and writing of the article	analysis and interpretation, data collection, figures and writing of the article	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Visualization|Writing - Original Draft	YES
6270739	25517346	E.R.P.	7	Conception and design, analysis and interpretation and writing of the article	Conception and design, analysis and interpretation and writing of the article	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
4416894	25932965	HCW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416894	25932965	HCW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4416894	25932965	HCW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416894	25932965	SPH	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4416894	25932965	SPH	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416894	25932965	WSL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416894	25932965	WSL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416894	25932965	WSL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416894	25932965	WSL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3203476	22073377	All authors	2	were involved in drafting the article or revising it critically for important intellectual content and approved the final version	were involved in drafting the article or revising it critically for important intellectual content and approved the final version	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3203476	22073377	CL	2	data acquisition|data analysis and interpretation|article drafting	data acquisition	Performed the experiments	Investigation	YES
3203476	22073377	CL	2	data acquisition|data analysis and interpretation|article drafting	data analysis and interpretation	Analyzed the data	Formal analysis	YES
3203476	22073377	CL	2	data acquisition|data analysis and interpretation|article drafting	article drafting	Wrote the paper	Writing - Original Draft	YES
3203476	22073377	FC	2	data acquisition	data acquisition	Performed the experiments	Investigation	YES
3203476	22073377	GM	2	study conception and design, data integrity and data analysis responsibility|article drafting	study conception and design, data integrity and data analysis responsibility	Conceived and designed the experiments|Analyzed the data	Conceptualization|Data curation|Formal analysis|Methodology	YES
3203476	22073377	GM	2	study conception and design, data integrity and data analysis responsibility|article drafting	article drafting	Wrote the paper	Writing - Original Draft	YES
3203476	22073377	MLC	2	article drafting	article drafting	Wrote the paper	Writing - Original Draft	YES
3203476	22073377	RL	2	data acquisition|data analysis and interpretation	data acquisition	Performed the experiments	Investigation	YES
3203476	22073377	RL	2	data acquisition|data analysis and interpretation	data analysis and interpretation	Analyzed the data	Formal analysis	YES
3203476	22073377	VC	2	data analysis and interpretation	data analysis and interpretation	Analyzed the data	Formal analysis	YES
1976394	17878948	BS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1976394	17878948	DA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1976394	17878948	DA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1976394	17878948	DA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1976394	17878948	MW	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1976394	17878948	MW	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1976394	17878948	TT	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4971191	27481791	All authors	2	contributed to the conceptual design of the essay, wrote sections, edited and approved the final product	contributed to the conceptual design of the essay, wrote sections, edited and approved the final product	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
5759210	29310578	AM	1	Analysis and interpretation of data|Statistical analysis	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
5759210	29310578	AM	1	Analysis and interpretation of data|Statistical analysis	Statistical analysis	Analyzed the data	Formal analysis	YES
5759210	29310578	DG	1	Administrative, technical, and material support	Administrative, technical, and material support	Performed the experiments	Investigation|Project administration	YES
5759210	29310578	GR	1	Acquisition of data|Statistical analysis	Acquisition of data	Performed the experiments	Investigation	YES
5759210	29310578	GR	1	Acquisition of data|Statistical analysis	Statistical analysis	Analyzed the data	Formal analysis	YES
5759210	29310578	HZ	1	Study concept and design|Acquisition of data|Drafting of the manuscript|Obtained funding	Study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5759210	29310578	HZ	1	Study concept and design|Acquisition of data|Drafting of the manuscript|Obtained funding	Acquisition of data	Performed the experiments	Investigation	YES
5759210	29310578	HZ	1	Study concept and design|Acquisition of data|Drafting of the manuscript|Obtained funding	Drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
5759210	29310578	HZ	1	Study concept and design|Acquisition of data|Drafting of the manuscript|Obtained funding	Obtained funding	-	Funding acquisition	YES
5759210	29310578	IGS	1	Study concept and design|Drafting of the manuscript|Obtained funding|Study supervision	Study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5759210	29310578	IGS	1	Study concept and design|Drafting of the manuscript|Obtained funding|Study supervision	Drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
5759210	29310578	IGS	1	Study concept and design|Drafting of the manuscript|Obtained funding|Study supervision	Obtained funding	-	Funding acquisition	YES
5759210	29310578	IGS	1	Study concept and design|Drafting of the manuscript|Obtained funding|Study supervision	Study supervision	-	Supervision	YES
5759210	29310578	JBL	1	Analysis and interpretation of data|Critical revision of the manuscript for important intellectual content|Obtained funding|Study supervision	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
5759210	29310578	JBL	1	Analysis and interpretation of data|Critical revision of the manuscript for important intellectual content|Obtained funding|Study supervision	Critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5759210	29310578	JBL	1	Analysis and interpretation of data|Critical revision of the manuscript for important intellectual content|Obtained funding|Study supervision	Obtained funding	-	Funding acquisition	YES
5759210	29310578	JBL	1	Analysis and interpretation of data|Critical revision of the manuscript for important intellectual content|Obtained funding|Study supervision	Study supervision	-	Supervision	YES
5759210	29310578	MB	1	Analysis and interpretation of data	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
5759210	29310578	ND	1	Administrative, technical, and material support	Administrative, technical, and material support	Performed the experiments	Investigation|Project administration	YES
5759210	29310578	NS	1	Analysis and interpretation of data|Critical revision of the manuscript for important intellectual content|Statistical analysis	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
5759210	29310578	NS	1	Analysis and interpretation of data|Critical revision of the manuscript for important intellectual content|Statistical analysis	Critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5759210	29310578	NS	1	Analysis and interpretation of data|Critical revision of the manuscript for important intellectual content|Statistical analysis	Statistical analysis	Analyzed the data	Formal analysis	YES
5759210	29310578	YNG	1	Acquisition of data|Critical revision of the manuscript for important intellectual content	Acquisition of data	Performed the experiments	Investigation	YES
5759210	29310578	YNG	1	Acquisition of data|Critical revision of the manuscript for important intellectual content	Critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
6331724	30559329	AF	2	performed most of the experiments|wrote the manuscript	performed most of the experiments	Performed the experiments	Investigation	YES
6331724	30559329	AF	2	performed most of the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6331724	30559329	AM	2	helped with the quantification of the data	helped with the quantification of the data	-	-	NO
6331724	30559329	AR	2	performed clem and tomography	performed clem and tomography	Performed the experiments	Investigation	YES
6331724	30559329	CDL	2	performed most of the experiments	performed most of the experiments	Performed the experiments	Investigation	YES
6331724	30559329	CS	2	designed the project|supervised the study|wrote the manuscript	designed the project	Conceived and designed the experiments	Methodology	YES
6331724	30559329	CS	2	designed the project|supervised the study|wrote the manuscript	supervised the study	-	Supervision	YES
6331724	30559329	CS	2	designed the project|supervised the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6331724	30559329	EF	2	performed most of the experiments	performed most of the experiments	Performed the experiments	Investigation	YES
6331724	30559329	EVA	2	generated and characterized halo-pc2 plasmids	generated and characterized halo-pc2 plasmids	Performed the experiments	Investigation	YES
6331724	30559329	GB	2	performed ha-pull-down studies	performed ha-pull-down studies	Performed the experiments	Investigation	YES
6331724	30559329	ID	2	supervised the study	supervised the study	-	Supervision	YES
6331724	30559329	IF	2	helped with the quantification of the data	helped with the quantification of the data	-	-	NO
6331724	30559329	LS	2	performed ha-pull-down studies	performed ha-pull-down studies	Performed the experiments	Investigation	YES
6331724	30559329	MADM	2	provided critical suggestions, protocols and reagents	provided critical suggestions, protocols and reagents	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Methodology|Resources	YES
6331724	30559329	MI	2	helped with the quantification of the data	helped with the quantification of the data	-	-	NO
6331724	30559329	MM	2	supervised the study	supervised the study	-	Supervision	YES
6331724	30559329	MP	2	helped with the quantification of the data	helped with the quantification of the data	-	-	NO
6331724	30559329	MS	2	performed mass spectrometry experiments	performed mass spectrometry experiments	Performed the experiments	Investigation	YES
6331724	30559329	PG	2	performed mass spectrometry experiments	performed mass spectrometry experiments	Performed the experiments	Investigation	YES
4416895	25933195	DB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416895	25933195	DB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4416895	25933195	DB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416895	25933195	DF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the software used in analysis	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416895	25933195	DF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the software used in analysis	Performed the experiments	Performed the experiments	Investigation	YES
4416895	25933195	DF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the software used in analysis	Analyzed the data	Analyzed the data	Formal analysis	YES
4416895	25933195	DF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the software used in analysis	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416895	25933195	DF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the software used in analysis	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416895	25933195	DF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the software used in analysis	Designed the software used in analysis	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
4416895	25933195	RR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416895	25933195	RR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416895	25933195	RR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416895	25933195	RR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5809510	29472940	DZ	7	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5809510	29472940	HZ	7	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5809510	29472940	JZ	7	designed experiments|discussed and developed the study|wrote the paper	designed experiments	Conceived and designed the experiments	Methodology	YES
5809510	29472940	JZ	7	designed experiments|discussed and developed the study|wrote the paper	discussed and developed the study	-	-	NO
5809510	29472940	JZ	7	designed experiments|discussed and developed the study|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5809510	29472940	LH	7	designed experiments	designed experiments	Conceived and designed the experiments	Methodology	YES
5809510	29472940	LW	7	designed experiments|performed the experiments|analyzed the data|discussed and developed the study|wrote the paper	designed experiments	Conceived and designed the experiments	Methodology	YES
5809510	29472940	LW	7	designed experiments|performed the experiments|analyzed the data|discussed and developed the study|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5809510	29472940	LW	7	designed experiments|performed the experiments|analyzed the data|discussed and developed the study|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5809510	29472940	LW	7	designed experiments|performed the experiments|analyzed the data|discussed and developed the study|wrote the paper	discussed and developed the study	-	-	NO
5809510	29472940	LW	7	designed experiments|performed the experiments|analyzed the data|discussed and developed the study|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5809510	29472940	SZ	7	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5809510	29472940	XC	7	discussed and developed the study|wrote the paper	discussed and developed the study	-	-	NO
5809510	29472940	XC	7	discussed and developed the study|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5809510	29472940	ZK	7	designed experiments|wrote the paper	designed experiments	Conceived and designed the experiments	Methodology	YES
5809510	29472940	ZK	7	designed experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5729180	29236192	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6270740	24879586	H.V.	2	conceived the computational study	conceived the computational study	Conceived and designed the experiments	Conceptualization|Formal analysis	YES
6270740	24879586	L.G.S.	2	performed the docking calculations and analysis	performed the docking calculations and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270740	24879586	NMR	2	of compounds 1 - 4	of compounds 1 - 4	Performed the experiments	Investigation	YES
6270740	24879586	P.R.A.	2	developed the atomic models of ipomotaosides and performed molecular dynamics and analysis|performed the docking calculations and analysis	developed the atomic models of ipomotaosides and performed molecular dynamics and analysis	Performed the experiments	Investigation|Methodology	YES
6270740	24879586	P.R.A.	2	developed the atomic models of ipomotaosides and performed molecular dynamics and analysis|performed the docking calculations and analysis	performed the docking calculations and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270740	24879586	Spectroscopic Data	2	of compounds 1 - 4	of compounds 1 - 4	Performed the experiments	Investigation	YES
4971192	27481792	Informal Science Education	1	Trails	Trails	-	-	NO
3203477	22073372	AL	2	contributing to reagents/analytic tools	contributing to reagents/analytic tools	Contributed reagents/materials/analysis tools	Resources	YES
3203477	22073372	CG	2	research performing|data analysis	research performing	Performed the experiments	Investigation	YES
3203477	22073372	CG	2	research performing|data analysis	data analysis	Analyzed the data	Formal analysis	YES
3203477	22073372	DF	2	research performing|data analysis	research performing	Performed the experiments	Investigation	YES
3203477	22073372	DF	2	research performing|data analysis	data analysis	Analyzed the data	Formal analysis	YES
3203477	22073372	FC	2	contributing to reagents/analytic tools	contributing to reagents/analytic tools	Contributed reagents/materials/analysis tools	Resources	YES
3203477	22073372	GF	2	research design, manuscript writing, revising and final approval|data analysis	research design, manuscript writing, revising and final approval	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
3203477	22073372	GF	2	research design, manuscript writing, revising and final approval|data analysis	data analysis	Analyzed the data	Formal analysis	YES
3203477	22073372	IM	2	research design, manuscript writing, revising and final approval|data analysis	research design, manuscript writing, revising and final approval	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
3203477	22073372	IM	2	research design, manuscript writing, revising and final approval|data analysis	data analysis	Analyzed the data	Formal analysis	YES
3203477	22073372	MC	2	research design, manuscript writing, revising and final approval|data analysis	research design, manuscript writing, revising and final approval	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
3203477	22073372	MC	2	research design, manuscript writing, revising and final approval|data analysis	data analysis	Analyzed the data	Formal analysis	YES
3203477	22073372	MUF	2	contributing to reagents/analytic tools	contributing to reagents/analytic tools	Contributed reagents/materials/analysis tools	Resources	YES
3203477	22073372	PVE	2	research design, manuscript writing, revising and final approval|research performing|data analysis	research design, manuscript writing, revising and final approval	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
3203477	22073372	PVE	2	research design, manuscript writing, revising and final approval|research performing|data analysis	research performing	Performed the experiments	Investigation	YES
3203477	22073372	PVE	2	research design, manuscript writing, revising and final approval|research performing|data analysis	data analysis	Analyzed the data	Formal analysis	YES
3203477	22073372	SN	2	research design, manuscript writing, revising and final approval|research performing|data analysis	research design, manuscript writing, revising and final approval	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
3203477	22073372	SN	2	research design, manuscript writing, revising and final approval|research performing|data analysis	research performing	Performed the experiments	Investigation	YES
3203477	22073372	SN	2	research design, manuscript writing, revising and final approval|research performing|data analysis	data analysis	Analyzed the data	Formal analysis	YES
3203477	22073372	TC	2	research performing|data analysis	research performing	Performed the experiments	Investigation	YES
3203477	22073372	TC	2	research performing|data analysis	data analysis	Analyzed the data	Formal analysis	YES
4416896	25933023	AL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416896	25933023	AL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416896	25933023	AL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416896	25933023	AL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416896	25933023	MK	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416896	25933023	MK	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416896	25933023	SH	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416896	25933023	SH	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1976395	17878949	AM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1976395	17878949	AM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1976395	17878949	AM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1976395	17878949	AS	PLoS5	Provided sequencing	Provided sequencing	Performed the experiments	Investigation	YES
1976395	17878949	DM	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1976395	17878949	DM	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1976395	17878949	FR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1976395	17878949	FR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1976395	17878949	FR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1976395	17878949	FR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1976395	17878949	GG	PLoS5	Provided sequencing	Provided sequencing	Performed the experiments	Investigation	YES
1976395	17878949	JA	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1976395	17878949	PL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1976395	17878949	PL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1976395	17878949	PL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4637059	26583134	Jianbin Zhong	2	contributed equally to this work	contributed equally to this work	-	-	NO
4637059	26583134	Shengnuo Fan	2	contributed equally to this work	contributed equally to this work	-	-	NO
5759245	29310597	AY	2	contributed to the bioinformatics analysis and advised on the project|contributed to drafting the manuscript	contributed to the bioinformatics analysis and advised on the project	-	Formal analysis	YES
5759245	29310597	AY	2	contributed to the bioinformatics analysis and advised on the project|contributed to drafting the manuscript	contributed to drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
5759245	29310597	All authors	2	read, commented on and approved the final version of the manuscript	read, commented on and approved the final version of the manuscript	-	-	NO
5759245	29310597	CEA	2	contributed to experimental design, acquired and/or collected samples, and led fish rearing	contributed to experimental design, acquired and/or collected samples, and led fish rearing	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources	YES
5759245	29310597	JJA	2	assembled the sequence data and constructed the initial assemblies	assembled the sequence data and constructed the initial assemblies	Performed the experiments	Investigation	YES
5759245	29310597	KRE	2	acquired and /or collected samples|conceived and supervised the study|contributed to drafting the manuscript	acquired and /or collected samples	Performed the experiments	Investigation	YES
5759245	29310597	KRE	2	acquired and /or collected samples|conceived and supervised the study|contributed to drafting the manuscript	conceived and supervised the study	Conceived and designed the experiments	Conceptualization|Supervision	YES
5759245	29310597	KRE	2	acquired and /or collected samples|conceived and supervised the study|contributed to drafting the manuscript	contributed to drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
5759245	29310597	MC	2	reared and sampled the specimens used in the study, executed the bioinformatics pipelines, performed data analysis and drafted the manuscript	reared and sampled the specimens used in the study, executed the bioinformatics pipelines, performed data analysis and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5759245	29310597	PH	2	generated rna seq data and assessed quality and contributed to making the initial assemblies|conceived and supervised the study	generated rna seq data and assessed quality and contributed to making the initial assemblies	Performed the experiments	Data curation|Investigation|Validation	YES
5759245	29310597	PH	2	generated rna seq data and assessed quality and contributed to making the initial assemblies|conceived and supervised the study	conceived and supervised the study	Conceived and designed the experiments	Conceptualization|Supervision	YES
6331727	30523147	ACZ	2	designed and created the ki67-fucci system	designed and created the ki67-fucci system	Conceived and designed the experiments	-	YES
6331727	30523147	AMJ	2	prepared glis2 knockout mice and related reagents	prepared glis2 knockout mice and related reagents	Contributed reagents/materials/analysis tools	Resources	YES
6331727	30523147	AW	2	prepared rosa and ert2 ift88 mice	prepared rosa and ert2 ift88 mice	-	-	NO
6331727	30523147	BH	2	performed experiments, and collected and analyzed data|conceived and designed most of the experiments reported, analyzed data and wrote the manuscript	performed experiments, and collected and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6331727	30523147	BH	2	performed experiments, and collected and analyzed data|conceived and designed most of the experiments reported, analyzed data and wrote the manuscript	conceived and designed most of the experiments reported, analyzed data and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
6331727	30523147	CRC	2	prepared rosa and ert2 ift88 mice	prepared rosa and ert2 ift88 mice	-	-	NO
6331727	30523147	CT	2	provided guidance throughout the works	provided guidance throughout the works	-	Supervision	YES
6331727	30523147	DC	2	conceived and designed most of the experiments reported, analyzed data and wrote the manuscript	conceived and designed most of the experiments reported, analyzed data and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
6331727	30523147	DL	2	prepared glis2 knockout mice and related reagents	prepared glis2 knockout mice and related reagents	Contributed reagents/materials/analysis tools	Resources	YES
6331727	30523147	DS	2	performed experiments, and collected and analyzed data	performed experiments, and collected and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6331727	30523147	HJ	2	prepared glis2 knockout mice and related reagents	prepared glis2 knockout mice and related reagents	Contributed reagents/materials/analysis tools	Resources	YES
6331727	30523147	HZ	2	performed experiments, and collected and analyzed data	performed experiments, and collected and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6331727	30523147	JK	2	performed experiments, and collected and analyzed data	performed experiments, and collected and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6331727	30523147	JVW	2	performed experiments, and collected and analyzed data	performed experiments, and collected and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6331727	30523147	KJL	2	assisted experimental design	assisted experimental design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6331727	30523147	KT	2	performed experiments, and collected and analyzed data	performed experiments, and collected and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6331727	30523147	MA	2	prepared glis2 knockout mice and related reagents	prepared glis2 knockout mice and related reagents	Contributed reagents/materials/analysis tools	Resources	YES
6331727	30523147	ODK	2	prepared bmi1 knockout mice	prepared bmi1 knockout mice	-	-	NO
6331727	30523147	PC	2	prepared flox/flox prom1 knockout mice	prepared flox/flox prom1 knockout mice	-	-	NO
6331727	30523147	PM	2	prepared bmi1 knockout mice	prepared bmi1 knockout mice	-	-	NO
6331727	30523147	PRCG	2	performed experiments, and collected and analyzed data	performed experiments, and collected and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6331727	30523147	SEM	2	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
6331727	30523147	SL	2	assisted experimental design	assisted experimental design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6331727	30523147	TG	2	performed experiments, and collected and analyzed data	performed experiments, and collected and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6331727	30523147	WBH	2	conceived and designed most of the experiments reported, analyzed data and wrote the manuscript	conceived and designed most of the experiments reported, analyzed data and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
6331727	30523147	XW	2	prepared bmi1 knockout mice	prepared bmi1 knockout mice	-	-	NO
6331727	30523147	YG	2	performed experiments, and collected and analyzed data	performed experiments, and collected and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270741	25153878	All authors	2	discussed, edited and approved the final version	discussed, edited and approved the final version	Wrote the paper	Writing - Review & Editing	YES
6270741	25153878	C.Y.C.	2	designed the research|wrote the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
6270741	25153878	C.Y.C.	2	designed the research|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6270741	25153878	P.J.S.	2	performed the experimental work	performed the experimental work	Performed the experiments	Investigation	YES
6270741	25153878	W.H.W.	2	performed the experimental work	performed the experimental work	Performed the experiments	Investigation	YES
6270741	25153878	Y.H.K.	2	designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
4416897	25933002	GE	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416897	25933002	GE	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416897	25933002	GE	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416897	25933002	GE	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416897	25933002	KR	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416897	25933002	KR	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416897	25933002	KR	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416897	25933002	MT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416897	25933002	MT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416897	25933002	MT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416897	25933002	MT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416897	25933002	MT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416897	25933002	RT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416897	25933002	RT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416897	25933002	RT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416897	25933002	RT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416897	25933002	RT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416897	25933002	SWG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416897	25933002	SWG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416897	25933002	SWG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416897	25933002	SWG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5730542	29242997	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5730542	29242997	DKO	PLoS52	designed the experiments, interpreted the results, and wrote the manuscript	designed the experiments, interpreted the results, and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5730542	29242997	JHC	PLoS52	designed the experiments, interpreted the results, and wrote the manuscript|performed the experiments	designed the experiments, interpreted the results, and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5730542	29242997	JHC	PLoS52	designed the experiments, interpreted the results, and wrote the manuscript|performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5730542	29242997	KCS	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5730542	29242997	KWL	PLoS52	designed the experiments, interpreted the results, and wrote the manuscript	designed the experiments, interpreted the results, and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5730542	29242997	MJS	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5730542	29242997	The authors	PLoS52	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5809773	29472943	AG-E	2	agreed to contribute this review and participated in delineating the content of the topic, and in the writing and preparation of figures	agreed to contribute this review and participated in delineating the content of the topic, and in the writing and preparation of figures	Wrote the paper	Visualization	YES
5809773	29472943	CB	2	agreed to contribute this review and participated in delineating the content of the topic, and in the writing and preparation of figures	agreed to contribute this review and participated in delineating the content of the topic, and in the writing and preparation of figures	Wrote the paper	Visualization	YES
5809773	29472943	EM	2	agreed to contribute this review and participated in delineating the content of the topic, and in the writing and preparation of figures	agreed to contribute this review and participated in delineating the content of the topic, and in the writing and preparation of figures	Wrote the paper	Visualization	YES
5809773	29472943	JJ	2	agreed to contribute this review and participated in delineating the content of the topic, and in the writing and preparation of figures	agreed to contribute this review and participated in delineating the content of the topic, and in the writing and preparation of figures	Wrote the paper	Visualization	YES
5809773	29472943	JR	2	agreed to contribute this review and participated in delineating the content of the topic, and in the writing and preparation of figures	agreed to contribute this review and participated in delineating the content of the topic, and in the writing and preparation of figures	Wrote the paper	Visualization	YES
5809773	29472943	MB	2	agreed to contribute this review and participated in delineating the content of the topic, and in the writing and preparation of figures	agreed to contribute this review and participated in delineating the content of the topic, and in the writing and preparation of figures	Wrote the paper	Visualization	YES
5809773	29472943	MN	2	agreed to contribute this review and participated in delineating the content of the topic, and in the writing and preparation of figures	agreed to contribute this review and participated in delineating the content of the topic, and in the writing and preparation of figures	Wrote the paper	Visualization	YES
1976549	17895980	CB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1976549	17895980	CB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1976549	17895980	CB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1976549	17895980	CB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1976549	17895980	DP	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1976549	17895980	DP	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4637060	26583137	Carlos Prados-Frutos	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
4637060	26583137	Jose Antonio Bea	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
4971193	27481793	All authors	2	gave final approval for publication	gave final approval for publication	-	-	NO
4971193	27481793	H.M.	2	provided an enormous number of specimens	provided an enormous number of specimens	Performed the experiments	Investigation	YES
4971193	27481793	K.M.K.	2	conceived of the work and wrote the paper	conceived of the work and wrote the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4971193	27481793	O.S.F.	2	curated most of the specimens and facilitated sampling in their respective museums	curated most of the specimens and facilitated sampling in their respective museums	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
4971193	27481793	P.B.F.	2	conceived of the work and wrote the paper|wrote the scripts and analysed the data	conceived of the work and wrote the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4971193	27481793	P.B.F.	2	conceived of the work and wrote the paper|wrote the scripts and analysed the data	wrote the scripts and analysed the data	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Software|Writing - Original Draft	YES
4971193	27481793	R.J.B.	2	curated most of the specimens and facilitated sampling in their respective museums	curated most of the specimens and facilitated sampling in their respective museums	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
4971193	27481793	R.W.H.	2	conceived of the work and wrote the paper|curated most of the specimens and facilitated sampling in their respective museums	conceived of the work and wrote the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4971193	27481793	R.W.H.	2	conceived of the work and wrote the paper|curated most of the specimens and facilitated sampling in their respective museums	curated most of the specimens and facilitated sampling in their respective museums	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
4971193	27481793	X.Z.	2	conceived of the work and wrote the paper|curated most of the specimens and facilitated sampling in their respective museums	conceived of the work and wrote the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4971193	27481793	X.Z.	2	conceived of the work and wrote the paper|curated most of the specimens and facilitated sampling in their respective museums	curated most of the specimens and facilitated sampling in their respective museums	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5759298	29310588	AJS	2	conceived and designed the study, conducted gwas bioinformatics analyses and analysis of the sdr pathway, and co-wrote the manuscript	conceived and designed the study, conducted gwas bioinformatics analyses and analysis of the sdr pathway, and co-wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5759298	29310588	ASS	2	conducted genome assembly/annotation and variant calling bioinformatics analyses and both contributed and revised the final manuscript	conducted genome assembly/annotation and variant calling bioinformatics analyses and both contributed and revised the final manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Formal analysis|Investigation|Writing - Review & Editing	YES
5759298	29310588	CMP	2	conceived and designed the study, performed the experiments, and co-wrote the manuscript	conceived and designed the study, performed the experiments, and co-wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Writing - Original Draft	YES
5759298	29310588	JRH	2	conceived and designed the experiment, edited the manuscript, and supervised the research	conceived and designed the experiment, edited the manuscript, and supervised the research	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Supervision|Writing - Review & Editing	YES
5759298	29310588	OW	2	coordinated specimen collection and collected biological data on the specimens	coordinated specimen collection and collected biological data on the specimens	Performed the experiments	Investigation|Project administration	YES
5759298	29310588	SOG	2	coordinated specimen collection and collected biological data on the specimens	coordinated specimen collection and collected biological data on the specimens	Performed the experiments	Investigation|Project administration	YES
6270742	24514746	The authors	2	are contributed equally to this work	are contributed equally to this work	-	-	NO
3284148	22193293	all authors	2	contributed equally to the manuscript conception, design, revision and final approval	contributed equally to the manuscript conception, design, revision and final approval	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
6356060	30478192	AC	2	analysed the deep sequencing data	analysed the deep sequencing data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6356060	30478192	AJD	2	identified and created the primpol mutant cdnas	identified and created the primpol mutant cdnas	Performed the experiments	Investigation	YES
6356060	30478192	GG	2	analysed the deep sequencing data	analysed the deep sequencing data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6356060	30478192	JES	2	conceived the study and wrote the paper with input from all authors	conceived the study and wrote the paper with input from all authors	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
6356060	30478192	SS	2	conceived the study and wrote the paper with input from all authors|performed all the experiments|performed the rna dip-seq experiments	conceived the study and wrote the paper with input from all authors	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
6356060	30478192	SS	2	conceived the study and wrote the paper with input from all authors|performed all the experiments|performed the rna dip-seq experiments	performed all the experiments	Performed the experiments	Investigation	YES
6356060	30478192	SS	2	conceived the study and wrote the paper with input from all authors|performed all the experiments|performed the rna dip-seq experiments	performed the rna dip-seq experiments	Performed the experiments	Investigation	YES
6356060	30478192	TAG	2	identified and created the primpol mutant cdnas	identified and created the primpol mutant cdnas	Performed the experiments	Investigation	YES
4416898	25933204	ACC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416898	25933204	ACC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416898	25933204	ACC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416898	25933204	ACC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416898	25933204	AH	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416898	25933204	AH	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416898	25933204	AH	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416898	25933204	FK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416898	25933204	FK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416898	25933204	FK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416898	25933204	JM	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416898	25933204	MWP	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416898	25933204	WRF	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416898	25933204	WRF	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416898	25933204	WRF	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5736513	29260432	All authors	2	read and approved the final manuscript|agree with this article published	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5736513	29260432	All authors	2	read and approved the final manuscript|agree with this article published	agree with this article published	-	-	NO
5736513	29260432	HM	2	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5736513	29260432	LL	2	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5736513	29260432	MY	2	assisted in the experiment and collected data	assisted in the experiment and collected data	Performed the experiments	Investigation	YES
5736513	29260432	QS	2	performed the experiments, sorted data and written the manuscript	performed the experiments, sorted data and written the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5736513	29260432	TJ	2	assisted in the experiment and collected data	assisted in the experiment and collected data	Performed the experiments	Investigation	YES
5736513	29260432	YY	2	assisted in the experiment and collected data	assisted in the experiment and collected data	Performed the experiments	Investigation	YES
5809869	29472936	CR	7	Designed the experiments|Assembled and purified the germplasm collection|Performed field evaluations and/or data analyses|Conceived the manuscript|Wrote the manuscript|Edited and provided critical review of the manuscript|Read and approved the final manuscript	Designed the experiments	Conceived and designed the experiments	Methodology	YES
5809869	29472936	CR	7	Designed the experiments|Assembled and purified the germplasm collection|Performed field evaluations and/or data analyses|Conceived the manuscript|Wrote the manuscript|Edited and provided critical review of the manuscript|Read and approved the final manuscript	Assembled and purified the germplasm collection	Performed the experiments	Investigation	YES
5809869	29472936	CR	7	Designed the experiments|Assembled and purified the germplasm collection|Performed field evaluations and/or data analyses|Conceived the manuscript|Wrote the manuscript|Edited and provided critical review of the manuscript|Read and approved the final manuscript	Performed field evaluations and/or data analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5809869	29472936	CR	7	Designed the experiments|Assembled and purified the germplasm collection|Performed field evaluations and/or data analyses|Conceived the manuscript|Wrote the manuscript|Edited and provided critical review of the manuscript|Read and approved the final manuscript	Conceived the manuscript	Conceived and designed the experiments	Conceptualization	YES
5809869	29472936	CR	7	Designed the experiments|Assembled and purified the germplasm collection|Performed field evaluations and/or data analyses|Conceived the manuscript|Wrote the manuscript|Edited and provided critical review of the manuscript|Read and approved the final manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5809869	29472936	CR	7	Designed the experiments|Assembled and purified the germplasm collection|Performed field evaluations and/or data analyses|Conceived the manuscript|Wrote the manuscript|Edited and provided critical review of the manuscript|Read and approved the final manuscript	Edited and provided critical review of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5809869	29472936	CR	7	Designed the experiments|Assembled and purified the germplasm collection|Performed field evaluations and/or data analyses|Conceived the manuscript|Wrote the manuscript|Edited and provided critical review of the manuscript|Read and approved the final manuscript	Read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5809869	29472936	DV	7	Assembled and purified the germplasm collection|Performed field evaluations and/or data analyses|Edited and provided critical review of the manuscript|Read and approved the final manuscript	Assembled and purified the germplasm collection	Performed the experiments	Investigation	YES
5809869	29472936	DV	7	Assembled and purified the germplasm collection|Performed field evaluations and/or data analyses|Edited and provided critical review of the manuscript|Read and approved the final manuscript	Performed field evaluations and/or data analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5809869	29472936	DV	7	Assembled and purified the germplasm collection|Performed field evaluations and/or data analyses|Edited and provided critical review of the manuscript|Read and approved the final manuscript	Edited and provided critical review of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5809869	29472936	DV	7	Assembled and purified the germplasm collection|Performed field evaluations and/or data analyses|Edited and provided critical review of the manuscript|Read and approved the final manuscript	Read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5809869	29472936	JS	7	Performed field evaluations and/or data analyses|Conceived the manuscript|Wrote the manuscript|Edited and provided critical review of the manuscript|Read and approved the final manuscript	Performed field evaluations and/or data analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5809869	29472936	JS	7	Performed field evaluations and/or data analyses|Conceived the manuscript|Wrote the manuscript|Edited and provided critical review of the manuscript|Read and approved the final manuscript	Conceived the manuscript	Conceived and designed the experiments	Conceptualization	YES
5809869	29472936	JS	7	Performed field evaluations and/or data analyses|Conceived the manuscript|Wrote the manuscript|Edited and provided critical review of the manuscript|Read and approved the final manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5809869	29472936	JS	7	Performed field evaluations and/or data analyses|Conceived the manuscript|Wrote the manuscript|Edited and provided critical review of the manuscript|Read and approved the final manuscript	Edited and provided critical review of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5809869	29472936	JS	7	Performed field evaluations and/or data analyses|Conceived the manuscript|Wrote the manuscript|Edited and provided critical review of the manuscript|Read and approved the final manuscript	Read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5809869	29472936	MS	7	Performed field evaluations and/or data analyses|Conceived the manuscript|Edited and provided critical review of the manuscript|Read and approved the final manuscript	Performed field evaluations and/or data analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5809869	29472936	MS	7	Performed field evaluations and/or data analyses|Conceived the manuscript|Edited and provided critical review of the manuscript|Read and approved the final manuscript	Conceived the manuscript	Conceived and designed the experiments	Conceptualization	YES
5809869	29472936	MS	7	Performed field evaluations and/or data analyses|Conceived the manuscript|Edited and provided critical review of the manuscript|Read and approved the final manuscript	Edited and provided critical review of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5809869	29472936	MS	7	Performed field evaluations and/or data analyses|Conceived the manuscript|Edited and provided critical review of the manuscript|Read and approved the final manuscript	Read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
1976550	17895969	AA	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1976550	17895969	AH	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1976550	17895969	AH	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1976550	17895969	AO	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1976550	17895969	AU	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1976550	17895969	AV	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1976550	17895969	BM	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1976550	17895969	CB	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1976550	17895969	CB	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1976550	17895969	CK	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1976550	17895969	CK	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1976550	17895969	DM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1976550	17895969	DM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1976550	17895969	DN	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1976550	17895969	FK	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1976550	17895969	GF	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1976550	17895969	GF	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1976550	17895969	GW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1976550	17895969	GW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1976550	17895969	GW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1976550	17895969	GW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1976550	17895969	HD	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1976550	17895969	HD	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1976550	17895969	HJ	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1976550	17895969	HJ	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1976550	17895969	HZ	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1976550	17895969	ID	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1976550	17895969	JG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1976550	17895969	JG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1976550	17895969	JG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1976550	17895969	JP	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1976550	17895969	JS	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1976550	17895969	KC	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1976550	17895969	KV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1976550	17895969	KV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1976550	17895969	KV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1976550	17895969	KV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1976550	17895969	LB	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1976550	17895969	LG	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1976550	17895969	LN	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1976550	17895969	LN	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1976550	17895969	LP	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1976550	17895969	LP	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1976550	17895969	MF	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1976550	17895969	MF	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1976550	17895969	MH	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1976550	17895969	MH	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1976550	17895969	MT	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1976550	17895969	OI	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1976550	17895969	PB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1976550	17895969	PB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1976550	17895969	PB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1976550	17895969	PE	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1976550	17895969	SD	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1976550	17895969	SD	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1976550	17895969	SH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1976550	17895969	SH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1976550	17895969	SL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1976550	17895969	SL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1976550	17895969	SY	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1976550	17895969	SY	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1976550	17895969	SY	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1976550	17895969	WL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1976550	17895969	WL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1976550	17895969	WN	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1976550	17895969	XQ	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1976550	17895969	XQ	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1976550	17895969	YD	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1976550	17895969	YD	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1976550	17895969	YL	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5759835	29316879	ALFL	2	interpreted the results and drafted the manuscript|helped to draft and revise the manuscript	interpreted the results and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5759835	29316879	ALFL	2	interpreted the results and drafted the manuscript|helped to draft and revise the manuscript	helped to draft and revise the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5759835	29316879	DPM	2	conceived and designed the experiment|interpreted the results and drafted the manuscript|helped to draft and revise the manuscript	conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5759835	29316879	DPM	2	conceived and designed the experiment|interpreted the results and drafted the manuscript|helped to draft and revise the manuscript	interpreted the results and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5759835	29316879	DPM	2	conceived and designed the experiment|interpreted the results and drafted the manuscript|helped to draft and revise the manuscript	helped to draft and revise the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5759835	29316879	EP	2	conceived and designed the experiment|carried out the data analyses|interpreted the results and drafted the manuscript	conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5759835	29316879	EP	2	conceived and designed the experiment|carried out the data analyses|interpreted the results and drafted the manuscript	carried out the data analyses	Analyzed the data	Formal analysis	YES
5759835	29316879	EP	2	conceived and designed the experiment|carried out the data analyses|interpreted the results and drafted the manuscript	interpreted the results and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5759835	29316879	FB	2	conceived and designed the experiment|carried out the data analyses|interpreted the results and drafted the manuscript	conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5759835	29316879	FB	2	conceived and designed the experiment|carried out the data analyses|interpreted the results and drafted the manuscript	carried out the data analyses	Analyzed the data	Formal analysis	YES
5759835	29316879	FB	2	conceived and designed the experiment|carried out the data analyses|interpreted the results and drafted the manuscript	interpreted the results and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5759835	29316879	JCCP	2	conceived and designed the experiment|interpreted the results and drafted the manuscript|helped to draft and revise the manuscript	conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5759835	29316879	JCCP	2	conceived and designed the experiment|interpreted the results and drafted the manuscript|helped to draft and revise the manuscript	interpreted the results and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5759835	29316879	JCCP	2	conceived and designed the experiment|interpreted the results and drafted the manuscript|helped to draft and revise the manuscript	helped to draft and revise the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5759835	29316879	MAM	2	conceived and designed the experiment|interpreted the results and drafted the manuscript|helped to draft and revise the manuscript	conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5759835	29316879	MAM	2	conceived and designed the experiment|interpreted the results and drafted the manuscript|helped to draft and revise the manuscript	interpreted the results and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5759835	29316879	MAM	2	conceived and designed the experiment|interpreted the results and drafted the manuscript|helped to draft and revise the manuscript	helped to draft and revise the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5759835	29316879	MVGBS	2	conceived and designed the experiment|interpreted the results and drafted the manuscript|helped to draft and revise the manuscript	conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5759835	29316879	MVGBS	2	conceived and designed the experiment|interpreted the results and drafted the manuscript|helped to draft and revise the manuscript	interpreted the results and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5759835	29316879	MVGBS	2	conceived and designed the experiment|interpreted the results and drafted the manuscript|helped to draft and revise the manuscript	helped to draft and revise the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5759835	29316879	NBS	2	interpreted the results and drafted the manuscript|helped to draft and revise the manuscript	interpreted the results and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5759835	29316879	NBS	2	interpreted the results and drafted the manuscript|helped to draft and revise the manuscript	helped to draft and revise the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5759835	29316879	RI	2	interpreted the results and drafted the manuscript|helped to draft and revise the manuscript	interpreted the results and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5759835	29316879	RI	2	interpreted the results and drafted the manuscript|helped to draft and revise the manuscript	helped to draft and revise the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5759835	29316879	RVV	2	carried out the data analyses|interpreted the results and drafted the manuscript|helped to draft and revise the manuscript	carried out the data analyses	Analyzed the data	Formal analysis	YES
5759835	29316879	RVV	2	carried out the data analyses|interpreted the results and drafted the manuscript|helped to draft and revise the manuscript	interpreted the results and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5759835	29316879	RVV	2	carried out the data analyses|interpreted the results and drafted the manuscript|helped to draft and revise the manuscript	helped to draft and revise the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6270743	25429558	D.K.	2	performed experimental work|analyzed the experimental data, and all authors wrote the manuscript and approved the final version	performed experimental work	Performed the experiments	Investigation	YES
6270743	25429558	D.K.	2	performed experimental work|analyzed the experimental data, and all authors wrote the manuscript and approved the final version	analyzed the experimental data, and all authors wrote the manuscript and approved the final version	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6270743	25429558	H.H.	2	performed experimental work|analyzed the experimental data, and all authors wrote the manuscript and approved the final version	performed experimental work	Performed the experiments	Investigation	YES
6270743	25429558	H.H.	2	performed experimental work|analyzed the experimental data, and all authors wrote the manuscript and approved the final version	analyzed the experimental data, and all authors wrote the manuscript and approved the final version	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6270743	25429558	J.F.	2	designed research	designed research	Conceived and designed the experiments	Methodology	YES
6270743	25429558	M.G.	2	designed research|analyzed the experimental data, and all authors wrote the manuscript and approved the final version	designed research	Conceived and designed the experiments	Methodology	YES
6270743	25429558	M.G.	2	designed research|analyzed the experimental data, and all authors wrote the manuscript and approved the final version	analyzed the experimental data, and all authors wrote the manuscript and approved the final version	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6270743	25429558	S.P.	2	designed research|performed experimental work	designed research	Conceived and designed the experiments	Methodology	YES
6270743	25429558	S.P.	2	designed research|performed experimental work	performed experimental work	Performed the experiments	Investigation	YES
4514687	26225120	AW	2	designed the study|analyzed data and wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
4514687	26225120	AW	2	designed the study|analyzed data and wrote the manuscript	analyzed data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4514687	26225120	All authors	2	read, provided input, and approved the final version of the manuscript	read, provided input, and approved the final version of the manuscript	-	-	NO
4514687	26225120	SK-S	2	designed the study|conducted the lm and clsm analyses|analyzed data and wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
4514687	26225120	SK-S	2	designed the study|conducted the lm and clsm analyses|analyzed data and wrote the manuscript	conducted the lm and clsm analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4514687	26225120	SK-S	2	designed the study|conducted the lm and clsm analyses|analyzed data and wrote the manuscript	analyzed data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4514687	26225120	TS	2	analyzed data and wrote the manuscript	analyzed data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4637064	26581422	Hongbo Shao	PLoS52	designed and supervised the study|revised and approved the final paper	designed and supervised the study	Conceived and designed the experiments	Methodology|Supervision	YES
4637064	26581422	Hongbo Shao	PLoS52	designed and supervised the study|revised and approved the final paper	revised and approved the final paper	Wrote the paper	Writing - Review & Editing	YES
4637064	26581422	Hongyan Wang	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4637064	26581422	Xiaoli Tang	PLoS52	conceived and designed the experiments|analyzed the data, carried out the rt-qpcr experiments, and wrote the paper|revised and approved the final paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4637064	26581422	Xiaoli Tang	PLoS52	conceived and designed the experiments|analyzed the data, carried out the rt-qpcr experiments, and wrote the paper|revised and approved the final paper	analyzed the data, carried out the rt-qpcr experiments, and wrote the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4637064	26581422	Xiaoli Tang	PLoS52	conceived and designed the experiments|analyzed the data, carried out the rt-qpcr experiments, and wrote the paper|revised and approved the final paper	revised and approved the final paper	Wrote the paper	Writing - Review & Editing	YES
4978870	27502377	All authors	2	gave final approval for publication	gave final approval for publication	-	-	NO
4978870	27502377	C.M.R.	2	conceived the idea for the paper and led the writing of the manuscript	conceived the idea for the paper and led the writing of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4978870	27502377	all other authors	2	reviewed the literature and contributed to sections of the text	reviewed the literature and contributed to sections of the text	Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
6356061	30630857	AC	7	performed experiments	performed experiments	Performed the experiments	Investigation	YES
6356061	30630857	ANS	7	conceived the project, designed experiments, and wrote the manuscript|performed experiments|analyzed data	conceived the project, designed experiments, and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
6356061	30630857	ANS	7	conceived the project, designed experiments, and wrote the manuscript|performed experiments|analyzed data	performed experiments	Performed the experiments	Investigation	YES
6356061	30630857	ANS	7	conceived the project, designed experiments, and wrote the manuscript|performed experiments|analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
6356061	30630857	AT	7	conceived the project, designed experiments, and wrote the manuscript	conceived the project, designed experiments, and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
6356061	30630857	CM-H	7	performed experiments	performed experiments	Performed the experiments	Investigation	YES
6356061	30630857	KM	7	performed experiments	performed experiments	Performed the experiments	Investigation	YES
6356061	30630857	LBo	7	performed experiments	performed experiments	Performed the experiments	Investigation	YES
6356061	30630857	LBu	7	provided tools and reagents for experiments	provided tools and reagents for experiments	Contributed reagents/materials/analysis tools	Resources	YES
6356061	30630857	LP	7	performed experiments	performed experiments	Performed the experiments	Investigation	YES
6356061	30630857	MR	7	developed tools for data analysis	developed tools for data analysis	Analyzed the data	Formal analysis	YES
6356061	30630857	PH	7	provided tools and reagents for experiments	provided tools and reagents for experiments	Contributed reagents/materials/analysis tools	Resources	YES
6356061	30630857	RM	7	conceived the project, designed experiments, and wrote the manuscript|analyzed data	conceived the project, designed experiments, and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
6356061	30630857	RM	7	conceived the project, designed experiments, and wrote the manuscript|analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
6356061	30630857	VR	7	performed experiments|analyzed data	performed experiments	Performed the experiments	Investigation	YES
6356061	30630857	VR	7	performed experiments|analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
1976551	17895968	ET	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1976551	17895968	JA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1976551	17895968	JA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1976551	17895968	JA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1976551	17895968	JA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1976551	17895968	JA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1976551	17895968	JP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1976551	17895968	KC	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1976551	17895968	TT	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416899	25933020	AC	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416899	25933020	AL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416899	25933020	AL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416899	25933020	AL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416899	25933020	BS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4416899	25933020	BS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416899	25933020	BZ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416899	25933020	BZ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416899	25933020	BZ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416899	25933020	BZ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416899	25933020	CA	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416899	25933020	CP	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4416899	25933020	CP	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4416899	25933020	CP	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416899	25933020	DB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416899	25933020	DB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416899	25933020	DB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416899	25933020	GC	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416899	25933020	GC	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416899	25933020	GH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416899	25933020	JMJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416899	25933020	JMJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416899	25933020	JMJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416899	25933020	JT	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416899	25933020	JT	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416899	25933020	KB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416899	25933020	KB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416899	25933020	KB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416899	25933020	LD	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416899	25933020	LD	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416899	25933020	LD	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416899	25933020	LV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416899	25933020	LV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416899	25933020	LV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416899	25933020	LV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416899	25933020	LY	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416899	25933020	LY	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416899	25933020	LY	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416899	25933020	LY	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416899	25933020	MA	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416899	25933020	MA	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416899	25933020	MN	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416899	25933020	MN	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416899	25933020	MN	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416899	25933020	MN	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416899	25933020	NB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416899	25933020	ND	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416899	25933020	ND	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416899	25933020	ND	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416899	25933020	ND	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416899	25933020	NH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416899	25933020	NH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416899	25933020	NH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416899	25933020	PW	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416899	25933020	PW	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416899	25933020	SK	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4416899	25933020	SK	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416899	25933020	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416899	25933020	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416899	25933020	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416899	25933020	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416899	25933020	VL	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416899	25933020	VL	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416899	25933020	VR	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416899	25933020	YC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416899	25933020	YC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416899	25933020	YC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5738328	29264716	All authors	2	contributed to the design of the experiments|read and approved the final manuscript	contributed to the design of the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5738328	29264716	All authors	2	contributed to the design of the experiments|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5738328	29264716	Food Science	2	at university of campinas	at university of campinas	-	-	NO
5738328	29264716	IVRO	2	performed the experiments and drafted the manuscript	performed the experiments and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5738328	29264716	MF	2	contributed with transcriptome data analysis	contributed with transcriptome data analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5738328	29264716	Ph.D.	2	studying in applied microbiology at sao paulo state university	studying in applied microbiology at sao paulo state university	Analyzed the data	Formal analysis	YES
5738328	29264716	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
6270744	25338177	C.F.	2	participated in the research design	participated in the research design	Conceived and designed the experiments	-	YES
6270744	25338177	I.P.	2	performed the research and analyzed the data	performed the research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270744	25338177	J.B.	2	participated in the research design	participated in the research design	Conceived and designed the experiments	-	YES
6270744	25338177	N.R.	2	participated in the research design	participated in the research design	Conceived and designed the experiments	-	YES
6270744	25338177	S.S.	2	participated in the research design|performed the research and analyzed the data	participated in the research design	Conceived and designed the experiments	-	YES
6270744	25338177	S.S.	2	participated in the research design|performed the research and analyzed the data	performed the research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270744	25338177	T.S.	2	performed the research and analyzed the data	performed the research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5810178	29472941	IP	2	contributed actively to the preliminary manuscript text, and designed figures and tables	contributed actively to the preliminary manuscript text, and designed figures and tables	Conceived and designed the experiments|Wrote the paper	Visualization|Writing - Original Draft	YES
5810178	29472941	JR	2	contributed actively to the preliminary manuscript text, and designed figures and tables	contributed actively to the preliminary manuscript text, and designed figures and tables	Conceived and designed the experiments|Wrote the paper	Visualization|Writing - Original Draft	YES
5810178	29472941	KK	2	outlined the manuscript area and prepared preliminary manuscript text	outlined the manuscript area and prepared preliminary manuscript text	Wrote the paper	Writing - Original Draft	YES
5810178	29472941	MU	2	contributed actively to the preliminary manuscript text, and designed figures and tables	contributed actively to the preliminary manuscript text, and designed figures and tables	Conceived and designed the experiments|Wrote the paper	Visualization|Writing - Original Draft	YES
5810178	29472941	PV	2	contributed actively to the preliminary manuscript text, and designed figures and tables	contributed actively to the preliminary manuscript text, and designed figures and tables	Conceived and designed the experiments|Wrote the paper	Visualization|Writing - Original Draft	YES
5810178	29472941	The other authors	2	contributed actively to the preliminary manuscript text, and designed figures and tables	contributed actively to the preliminary manuscript text, and designed figures and tables	Conceived and designed the experiments|Wrote the paper	Visualization|Writing - Original Draft	YES
5759876	29310579	CAR	2	provided essential reagents and materials and, revised the manuscript giving critically improvement|sought ethical approval for the studies from which the strains were derived	provided essential reagents and materials and, revised the manuscript giving critically improvement	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Review & Editing	YES
5759876	29310579	CAR	2	provided essential reagents and materials and, revised the manuscript giving critically improvement|sought ethical approval for the studies from which the strains were derived	sought ethical approval for the studies from which the strains were derived	Performed the experiments	Investigation	YES
5759876	29310579	CS	2	designed research and revised the manuscript giving critically improvement|has primary responsibility for final content	designed research and revised the manuscript giving critically improvement	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5759876	29310579	CS	2	designed research and revised the manuscript giving critically improvement|has primary responsibility for final content	has primary responsibility for final content	-	-	NO
5759876	29310579	DVS	2	designed research and revised the manuscript giving critically improvement	designed research and revised the manuscript giving critically improvement	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5759876	29310579	FB	2	conducted research, analysed data and wrote the paper	conducted research, analysed data and wrote the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5759876	29310579	MOCM	2	provided essential reagents and materials and, revised the manuscript giving critically improvement	provided essential reagents and materials and, revised the manuscript giving critically improvement	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Review & Editing	YES
5759876	29310579	RPR	2	designed research and revised the manuscript giving critically improvement	designed research and revised the manuscript giving critically improvement	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5759876	29310579	SA	2	conducted research, analysed data and wrote the paper	conducted research, analysed data and wrote the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
1976552	17895979	JS	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1976552	17895979	JS	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1976552	17895979	RC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1976552	17895979	RC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1976552	17895979	RC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1976552	17895979	SP	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1976552	17895979	SP	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1976552	17895979	WT	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1976552	17895979	WT	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1976552	17895979	WT	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4978873	27502380	All authors	2	provided intellectual content, data collection and analysis, and commented on the manuscript	provided intellectual content, data collection and analysis, and commented on the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
6356158	30573669	A.K.	2	conceived the study and wrote the manuscript|carried out the experiments	conceived the study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
6356158	30573669	A.K.	2	conceived the study and wrote the manuscript|carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
6356158	30573669	D.A.-R.	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
6356158	30573669	J.H.	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
6356158	30573669	M.P.	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
6356158	30573669	N.A.H.	2	contributed to design of experiments and writing of the manuscript	contributed to design of experiments and writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
6356158	30573669	R.J.	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
6356158	30573669	S.R.	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
6356158	30573669	S.W.	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
6270745	24762964	M.E.S.	7	principal investigator and corresponding author	principal investigator and corresponding author	Conceived and designed the experiments|Wrote the paper	Conceptualization|Funding acquisition|Writing - Original Draft	YES
6270745	24762964	R.C.D.	7	was only responsible for the 3d-qsar computational aspect which included analysis of results and write up	was only responsible for the 3d-qsar computational aspect which included analysis of results and write up	Analyzed the data|Wrote the paper	Formal analysis	YES
6270745	24762964	S.M.	7	Responsible for all of the computational experimental work and data analyses as well as was responsible for the entire manuscript write up from the cover page to the references	Responsible for all of the computational experimental work and data analyses as well as was responsible for the entire manuscript write up from the cover page to the references	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4416901	25933022	EWB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416901	25933022	EWB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416901	25933022	EWB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416901	25933022	EWB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416901	25933022	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416901	25933022	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416901	25933022	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416901	25933022	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416901	25933022	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416901	25933022	JW	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416901	25933022	JW	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4416901	25933022	JW	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5759888	29310583	HQQ	PLoS52	analysed data	analysed data	Analyzed the data	Formal analysis	YES
5759888	29310583	LLL	PLoS52	provided analysis softwares	provided analysis softwares	Contributed reagents/materials/analysis tools	Software	YES
5759888	29310583	LSN	PLoS52	analysed data	analysed data	Analyzed the data	Formal analysis	YES
5759888	29310583	MHT	PLoS52	designed research	designed research	Conceived and designed the experiments	Methodology	YES
5759888	29310583	PML	PLoS52	conducted research|analysed data|wrote the paper	conducted research	Performed the experiments	Investigation	YES
5759888	29310583	PML	PLoS52	conducted research|analysed data|wrote the paper	analysed data	Analyzed the data	Formal analysis	YES
5759888	29310583	PML	PLoS52	conducted research|analysed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5759888	29310583	ZJL	PLoS52	analysed data	analysed data	Analyzed the data	Formal analysis	YES
5810251	29472937	All authors	2	have reviewed and approved the final version of the manuscript and therefore are equally responsible for the integrity and accuracy of its content	have reviewed and approved the final version of the manuscript and therefore are equally responsible for the integrity and accuracy of its content	Wrote the paper	Writing - Review & Editing	YES
5810251	29472937	FC	2	performed total rna exaction	performed total rna exaction	Performed the experiments	Investigation	YES
5810251	29472937	HL	2	performed the first strand cdna synthesis	performed the first strand cdna synthesis	Performed the experiments	Investigation	YES
5810251	29472937	JZ	2	designed the project, acquired funding, and finalized the manuscript	designed the project, acquired funding, and finalized the manuscript	Conceived and designed the experiments|Wrote the paper	Funding acquisition|Methodology|Writing - Review & Editing	YES
5810251	29472937	KY	2	co-wrote the first draft of the manuscript|collected the young inflorescences of the ah population|performed the qrt-pcr assays	co-wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
5810251	29472937	KY	2	co-wrote the first draft of the manuscript|collected the young inflorescences of the ah population|performed the qrt-pcr assays	collected the young inflorescences of the ah population	Performed the experiments	Investigation	YES
5810251	29472937	KY	2	co-wrote the first draft of the manuscript|collected the young inflorescences of the ah population|performed the qrt-pcr assays	performed the qrt-pcr assays	Performed the experiments	Investigation	YES
5810251	29472937	MH	2	collected and processed the data used in this study	collected and processed the data used in this study	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5810251	29472937	PC	2	assisted and analyzed the data	assisted and analyzed the data	Analyzed the data	Formal analysis	YES
5810251	29472937	QP	2	performed total rna exaction	performed total rna exaction	Performed the experiments	Investigation	YES
5810251	29472937	RG	2	designed the project, acquired funding, and finalized the manuscript	designed the project, acquired funding, and finalized the manuscript	Conceived and designed the experiments|Wrote the paper	Funding acquisition|Methodology|Writing - Review & Editing	YES
5810251	29472937	SC	2	collected the young inflorescences of the ah population	collected the young inflorescences of the ah population	Performed the experiments	Investigation	YES
5810251	29472937	SF	2	collected and processed the data used in this study	collected and processed the data used in this study	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5810251	29472937	WL	2	assisted and analyzed the data	assisted and analyzed the data	Analyzed the data	Formal analysis	YES
5810251	29472937	WZ	2	performed the first strand cdna synthesis	performed the first strand cdna synthesis	Performed the experiments	Investigation	YES
5810251	29472937	XW	2	co-wrote the first draft of the manuscript|performed the qrt-pcr assays	co-wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
5810251	29472937	XW	2	co-wrote the first draft of the manuscript|performed the qrt-pcr assays	performed the qrt-pcr assays	Performed the experiments	Investigation	YES
5738332	29264772	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5738332	29264772	HBH	2	designed and performed most of the experiments	designed and performed most of the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5738332	29264772	HC	2	conceived the study|designed and performed most of the experiments	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5738332	29264772	HC	2	conceived the study|designed and performed most of the experiments	designed and performed most of the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5738332	29264772	HW	2	edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5738332	29264772	JJZ	2	conceived the study|designed and performed most of the experiments|wrote the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5738332	29264772	JJZ	2	conceived the study|designed and performed most of the experiments|wrote the manuscript	designed and performed most of the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5738332	29264772	JJZ	2	conceived the study|designed and performed most of the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5738332	29264772	MJC	2	edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5738332	29264772	MY	2	designed and performed most of the experiments|edited the manuscript	designed and performed most of the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5738332	29264772	MY	2	designed and performed most of the experiments|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5738332	29264772	ZYF	2	conceived the study|edited the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5738332	29264772	ZYF	2	conceived the study|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
1976556	17895971	AK	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1976556	17895971	AK	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1976556	17895971	AO	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1976556	17895971	AO	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1976556	17895971	AO	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1976556	17895971	CH	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1976556	17895971	DS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1976556	17895971	GB	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1976556	17895971	GB	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1976556	17895971	IB	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1976556	17895971	IP	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1976556	17895971	LT	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1976556	17895971	RH	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1976556	17895971	RM	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1976556	17895971	RM	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1976556	17895971	SJ	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1976556	17895971	SJ	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1976556	17895971	TE	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1976556	17895971	TG	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1976556	17895971	TY	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1976556	17895971	TY	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1976556	17895971	TY	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1976556	17895971	YH	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6376327	30643019	ALBP	PLoS52	designed research|performed experiments|performed afm experiments|analyzed the data|wrote the paper|supervised the project	designed research	Conceived and designed the experiments	Methodology	YES
6376327	30643019	ALBP	PLoS52	designed research|performed experiments|performed afm experiments|analyzed the data|wrote the paper|supervised the project	performed experiments	Performed the experiments	Investigation	YES
6376327	30643019	ALBP	PLoS52	designed research|performed experiments|performed afm experiments|analyzed the data|wrote the paper|supervised the project	performed afm experiments	Performed the experiments	Investigation	YES
6376327	30643019	ALBP	PLoS52	designed research|performed experiments|performed afm experiments|analyzed the data|wrote the paper|supervised the project	analyzed the data	Analyzed the data	Formal analysis	YES
6376327	30643019	ALBP	PLoS52	designed research|performed experiments|performed afm experiments|analyzed the data|wrote the paper|supervised the project	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6376327	30643019	ALBP	PLoS52	designed research|performed experiments|performed afm experiments|analyzed the data|wrote the paper|supervised the project	supervised the project	-	Supervision	YES
6376327	30643019	BWB	PLoS52	designed research|performed experiments|developed flow cytometry methodologies for outer/inner membrane permeabilization|analyzed the data|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
6376327	30643019	BWB	PLoS52	designed research|performed experiments|developed flow cytometry methodologies for outer/inner membrane permeabilization|analyzed the data|wrote the paper	performed experiments	Performed the experiments	Investigation	YES
6376327	30643019	BWB	PLoS52	designed research|performed experiments|developed flow cytometry methodologies for outer/inner membrane permeabilization|analyzed the data|wrote the paper	developed flow cytometry methodologies for outer/inner membrane permeabilization	Performed the experiments	Investigation|Methodology	YES
6376327	30643019	BWB	PLoS52	designed research|performed experiments|developed flow cytometry methodologies for outer/inner membrane permeabilization|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
6376327	30643019	BWB	PLoS52	designed research|performed experiments|developed flow cytometry methodologies for outer/inner membrane permeabilization|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6376327	30643019	BWH	PLoS52	designed research|analyzed the data|wrote the paper|supervised the project	designed research	Conceived and designed the experiments	Methodology	YES
6376327	30643019	BWH	PLoS52	designed research|analyzed the data|wrote the paper|supervised the project	analyzed the data	Analyzed the data	Formal analysis	YES
6376327	30643019	BWH	PLoS52	designed research|analyzed the data|wrote the paper|supervised the project	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6376327	30643019	BWH	PLoS52	designed research|analyzed the data|wrote the paper|supervised the project	supervised the project	-	Supervision	YES
6376327	30643019	DACH	PLoS52	designed research|performed experiments|performed afm experiments|analyzed the data|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
6376327	30643019	DACH	PLoS52	designed research|performed experiments|performed afm experiments|analyzed the data|wrote the paper	performed experiments	Performed the experiments	Investigation	YES
6376327	30643019	DACH	PLoS52	designed research|performed experiments|performed afm experiments|analyzed the data|wrote the paper	performed afm experiments	Performed the experiments	Investigation	YES
6376327	30643019	DACH	PLoS52	designed research|performed experiments|performed afm experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
6376327	30643019	DACH	PLoS52	designed research|performed experiments|performed afm experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6376327	30643019	DJD	PLoS52	designed research|performed experiments|analyzed the data	designed research	Conceived and designed the experiments	Methodology	YES
6376327	30643019	DJD	PLoS52	designed research|performed experiments|analyzed the data	performed experiments	Performed the experiments	Investigation	YES
6376327	30643019	DJD	PLoS52	designed research|performed experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
6376327	30643019	ESP	PLoS52	designed research|performed experiments|performed afm experiments|analyzed the data|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
6376327	30643019	ESP	PLoS52	designed research|performed experiments|performed afm experiments|analyzed the data|wrote the paper	performed experiments	Performed the experiments	Investigation	YES
6376327	30643019	ESP	PLoS52	designed research|performed experiments|performed afm experiments|analyzed the data|wrote the paper	performed afm experiments	Performed the experiments	Investigation	YES
6376327	30643019	ESP	PLoS52	designed research|performed experiments|performed afm experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
6376327	30643019	ESP	PLoS52	designed research|performed experiments|performed afm experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6376327	30643019	ETMB	PLoS52	designed research|performed experiments	designed research	Conceived and designed the experiments	Methodology	YES
6376327	30643019	ETMB	PLoS52	designed research|performed experiments	performed experiments	Performed the experiments	Investigation	YES
6376327	30643019	IB	PLoS52	designed research|performed experiments|performed afm experiments|analyzed the data|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
6376327	30643019	IB	PLoS52	designed research|performed experiments|performed afm experiments|analyzed the data|wrote the paper	performed experiments	Performed the experiments	Investigation	YES
6376327	30643019	IB	PLoS52	designed research|performed experiments|performed afm experiments|analyzed the data|wrote the paper	performed afm experiments	Performed the experiments	Investigation	YES
6376327	30643019	IB	PLoS52	designed research|performed experiments|performed afm experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
6376327	30643019	IB	PLoS52	designed research|performed experiments|performed afm experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6376327	30643019	MR	PLoS52	performed experiments	performed experiments	Performed the experiments	Investigation	YES
6376327	30643019	RDG	PLoS52	generated atomic models of c5 convertases and c5b6	generated atomic models of c5 convertases and c5b6	Performed the experiments	Investigation|Methodology	YES
6376327	30643019	SHMR	PLoS52	designed research|analyzed the data|wrote the paper|supervised the project	designed research	Conceived and designed the experiments	Methodology	YES
6376327	30643019	SHMR	PLoS52	designed research|analyzed the data|wrote the paper|supervised the project	analyzed the data	Analyzed the data	Formal analysis	YES
6376327	30643019	SHMR	PLoS52	designed research|analyzed the data|wrote the paper|supervised the project	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6376327	30643019	SHMR	PLoS52	designed research|analyzed the data|wrote the paper|supervised the project	supervised the project	-	Supervision	YES
5763532	29321003	AGE	2	assisted in data analysis	assisted in data analysis	Analyzed the data	Formal analysis	YES
5763532	29321003	D-EP	2	were responsible for the design, experimental procedure and interpretation of the 5-eu assay and provision of specialized reagents	were responsible for the design, experimental procedure and interpretation of the 5-eu assay and provision of specialized reagents	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5763532	29321003	E-SK	2	developed the cellular system|performed figure preparation	developed the cellular system	Performed the experiments	Investigation|Methodology	YES
5763532	29321003	E-SK	2	developed the cellular system|performed figure preparation	performed figure preparation	Performed the experiments	Investigation|Visualization	YES
5763532	29321003	EON	2	were responsible for the design, experimental procedure and interpretation of the 5-eu assay and provision of specialized reagents	were responsible for the design, experimental procedure and interpretation of the 5-eu assay and provision of specialized reagents	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5763532	29321003	FACS	2	analysis and chip	analysis and chip	-	-	NO
5763532	29321003	FMR	2	performed the cytogenetic analysis	performed the cytogenetic analysis	Performed the experiments	Investigation	YES
5763532	29321003	ISP	2	performed figure preparation	performed figure preparation	Performed the experiments	Investigation|Visualization	YES
5763532	29321003	JB	2	assisted in data analysis	assisted in data analysis	Analyzed the data	Formal analysis	YES
5763532	29321003	MC	2	performed the cytogenetic analysis	performed the cytogenetic analysis	Performed the experiments	Investigation	YES
5763532	29321003	SG	2	performed the cytogenetic analysis	performed the cytogenetic analysis	Performed the experiments	Investigation	YES
5763532	29321003	VGG	2	designed the experiments, supervised the project and wrote the manuscript	designed the experiments, supervised the project and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Original Draft	YES
6270746	24762965	D. Hong	2	designed the study|interpreted the results|drafted the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
6270746	24762965	D. Hong	2	designed the study|interpreted the results|drafted the manuscript	interpreted the results	Analyzed the data	Formal analysis	YES
6270746	24762965	D. Hong	2	designed the study|interpreted the results|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
6270746	24762965	J. Han	2	collected test data	collected test data	Performed the experiments	Investigation	YES
4416902	25932918	AD	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416902	25932918	AD	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416902	25932918	AD	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416902	25932918	EK	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416902	25932918	EK	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416902	25932918	EK	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416902	25932918	JW	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416902	25932918	JW	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416902	25932918	WE	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416902	25932918	WE	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416902	25932918	WE	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4637067	26583136	Menaka Hapugoda	2	was responsible for identification of field samples	was responsible for identification of field samples	Performed the experiments	Investigation	YES
4637067	26583136	Nayana Gunathilaka	2	was responsible for sample collection, identification of field samples, and writing the paper	was responsible for sample collection, identification of field samples, and writing the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4637067	26583136	Rajitha Wickremasinghe	2	was responsible for identification of field samples and data analysis	was responsible for identification of field samples and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4637067	26583136	Wimaladharma Abeyewickreme	2	was responsible for supervision of the surveillance programme and reviewing the paper	was responsible for supervision of the surveillance programme and reviewing the paper	Wrote the paper	Supervision|Writing - Review & Editing	YES
5810253	29472934	BT	4	BT designed the experiments: SG performed the experiments and analyzed the data: Paper was written by	BT designed the experiments: SG performed the experiments and analyzed the data: Paper was written by	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5810253	29472934	SG	4	BT designed the experiments: SG performed the experiments and analyzed the data: Paper was written by	BT designed the experiments: SG performed the experiments and analyzed the data: Paper was written by	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5741566	29273886	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5741566	29273886	BAC	2	conceived the project	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5741566	29273886	RS	2	conceived the project|performed major experiments, analyzed and interpreted the results	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5741566	29273886	RS	2	conceived the project|performed major experiments, analyzed and interpreted the results	performed major experiments, analyzed and interpreted the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5741566	29273886	SN	2	performed major experiments, analyzed and interpreted the results	performed major experiments, analyzed and interpreted the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5741566	29273886	SW	2	contributed to experimental designing of protein purification through chromatography	contributed to experimental designing of protein purification through chromatography	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5741566	29273886	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5741566	29273886	US	2	contributed to experimental designing of protein purification through chromatography	contributed to experimental designing of protein purification through chromatography	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4992713	27528779	All authors	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4992713	27528779	P.H.	2	acquired the longitudinal and transverse piv data|gathered the surface morphology data	acquired the longitudinal and transverse piv data	Performed the experiments	Investigation	YES
4992713	27528779	P.H.	2	acquired the longitudinal and transverse piv data|gathered the surface morphology data	gathered the surface morphology data	Performed the experiments	Investigation	YES
4992713	27528779	R.J.B.	2	gathered the surface morphology data	gathered the surface morphology data	Performed the experiments	Investigation	YES
4992713	27528779	T.N.	2	gathered the surface morphology data|performed the cfd simulations, field photography, morphology-fitting and conducted the bulk of the piv analysis|revised the manuscript	gathered the surface morphology data	Performed the experiments	Investigation	YES
4992713	27528779	T.N.	2	gathered the surface morphology data|performed the cfd simulations, field photography, morphology-fitting and conducted the bulk of the piv analysis|revised the manuscript	performed the cfd simulations, field photography, morphology-fitting and conducted the bulk of the piv analysis	Performed the experiments	Formal analysis|Investigation|Visualization	YES
4992713	27528779	T.N.	2	gathered the surface morphology data|performed the cfd simulations, field photography, morphology-fitting and conducted the bulk of the piv analysis|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
1976557	17895972	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1976557	17895972	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1976557	17895972	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1976557	17895972	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1976557	17895972	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1976557	17895972	DK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1976557	17895972	DK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1976557	17895972	DK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1976557	17895972	DK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1976557	17895972	GL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1976557	17895972	GL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1976557	17895972	GL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1976557	17895972	JE	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1976557	17895972	JE	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1976557	17895972	JY	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1976557	17895972	JY	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1976557	17895972	JY	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1976557	17895972	JY	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1976557	17895972	RD	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5763542	29325522	ARRF	2	managed and organized the fantom5 project	managed and organized the fantom5 project	-	Project administration	YES
5763542	29325522	COD	2	managed and organized the fantom5 project	managed and organized the fantom5 project	-	Project administration	YES
5763542	29325522	DG	2	generated samples for the time series|wrote the manuscript	generated samples for the time series	Performed the experiments	Investigation	YES
5763542	29325522	DG	2	generated samples for the time series|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5763542	29325522	DS	2	generated samples for the time series	generated samples for the time series	Performed the experiments	Investigation	YES
5763542	29325522	EA	2	performed data analysis	performed data analysis	Analyzed the data	Formal analysis	YES
5763542	29325522	ED	2	performed data analysis|wrote the manuscript	performed data analysis	Analyzed the data	Formal analysis	YES
5763542	29325522	ED	2	performed data analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5763542	29325522	HK	2	performed data analysis	performed data analysis	Analyzed the data	Formal analysis	YES
5763542	29325522	MI	2	generated the cage libraries	generated the cage libraries	Performed the experiments	Investigation	YES
5763542	29325522	PC	2	generated the cage libraries|managed and organized the fantom5 project	generated the cage libraries	Performed the experiments	Investigation	YES
5763542	29325522	PC	2	generated the cage libraries|managed and organized the fantom5 project	managed and organized the fantom5 project	-	Project administration	YES
5763542	29325522	PZ	2	generated samples for the time series|performed data analysis|performed biological validation experiments|wrote the manuscript	generated samples for the time series	Performed the experiments	Investigation	YES
5763542	29325522	PZ	2	generated samples for the time series|performed data analysis|performed biological validation experiments|wrote the manuscript	performed data analysis	Analyzed the data	Formal analysis	YES
5763542	29325522	PZ	2	generated samples for the time series|performed data analysis|performed biological validation experiments|wrote the manuscript	performed biological validation experiments	Performed the experiments	Investigation|Validation	YES
5763542	29325522	PZ	2	generated samples for the time series|performed data analysis|performed biological validation experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5763542	29325522	TH	2	generated samples for the time series	generated samples for the time series	Performed the experiments	Investigation	YES
5763542	29325522	TL	2	performed data analysis	performed data analysis	Analyzed the data	Formal analysis	YES
5763542	29325522	WH	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5763542	29325522	YH	2	managed and organized the fantom5 project	managed and organized the fantom5 project	-	Project administration	YES
3284234	22297438	GW	2	manuscript revision	manuscript revision	Wrote the paper	Writing - Review & Editing	YES
3284234	22297438	HC	2	contribution to reagents/materials/analysis tools	contribution to reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
3284234	22297438	HZ	2	experiments performing	experiments performing	Performed the experiments	Investigation	YES
3284234	22297438	JW	2	experiments performing	experiments performing	Performed the experiments	Investigation	YES
3284234	22297438	KT	2	manuscript revision	manuscript revision	Wrote the paper	Writing - Review & Editing	YES
3284234	22297438	LL	2	data analysis	data analysis	Analyzed the data	Formal analysis	YES
3284234	22297438	MX	2	contribution to reagents/materials/analysis tools	contribution to reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
3284234	22297438	QL	2	experiments performing|manuscript drafting	experiments performing	Performed the experiments	Investigation	YES
3284234	22297438	QL	2	experiments performing|manuscript drafting	manuscript drafting	Wrote the paper	Writing - Original Draft	YES
3284234	22297438	QW	2	experiments conceiving and design|contribution to reagents/materials/analysis tools|manuscript drafting	experiments conceiving and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
3284234	22297438	QW	2	experiments conceiving and design|contribution to reagents/materials/analysis tools|manuscript drafting	contribution to reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
3284234	22297438	QW	2	experiments conceiving and design|contribution to reagents/materials/analysis tools|manuscript drafting	manuscript drafting	Wrote the paper	Writing - Original Draft	YES
3284234	22297438	SL	2	contribution to reagents/materials/analysis tools	contribution to reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
3284234	22297438	XM	2	data analysis	data analysis	Analyzed the data	Formal analysis	YES
6396144	30737259	AL	2	performed the majority of experiments	performed the majority of experiments	Performed the experiments	Investigation	YES
6396144	30737259	AO	2	designed and supervised individual experiments	designed and supervised individual experiments	Conceived and designed the experiments	Methodology|Supervision	YES
6396144	30737259	AP	2	designed and supervised individual experiments	designed and supervised individual experiments	Conceived and designed the experiments	Methodology|Supervision	YES
6396144	30737259	AW	2	performed and evaluated individual experiments	performed and evaluated individual experiments	Performed the experiments	Investigation	YES
6396144	30737259	CC-M	2	performed and evaluated individual experiments	performed and evaluated individual experiments	Performed the experiments	Investigation	YES
6396144	30737259	CMR	2	performed and evaluated individual experiments	performed and evaluated individual experiments	Performed the experiments	Investigation	YES
6396144	30737259	CP	2	performed and evaluated individual experiments	performed and evaluated individual experiments	Performed the experiments	Investigation	YES
6396144	30737259	DJ	2	performed and evaluated individual experiments	performed and evaluated individual experiments	Performed the experiments	Investigation	YES
6396144	30737259	DM	2	performed the majority of experiments	performed the majority of experiments	Performed the experiments	Investigation	YES
6396144	30737259	ED	2	performed and evaluated individual experiments	performed and evaluated individual experiments	Performed the experiments	Investigation	YES
6396144	30737259	EF	2	performed and evaluated individual experiments	performed and evaluated individual experiments	Performed the experiments	Investigation	YES
6396144	30737259	GDR	2	designed and supervised the study|wrote the manuscript with contributions from all the authors	designed and supervised the study	Conceived and designed the experiments	Methodology|Supervision	YES
6396144	30737259	GDR	2	designed and supervised the study|wrote the manuscript with contributions from all the authors	wrote the manuscript with contributions from all the authors	Wrote the paper	Writing - Original Draft	YES
6396144	30737259	HMA	2	designed and supervised individual experiments	designed and supervised individual experiments	Conceived and designed the experiments	Methodology|Supervision	YES
6396144	30737259	HS	2	performed and evaluated individual experiments	performed and evaluated individual experiments	Performed the experiments	Investigation	YES
6396144	30737259	JB	2	performed and evaluated individual experiments	performed and evaluated individual experiments	Performed the experiments	Investigation	YES
6396144	30737259	JC	2	performed and evaluated individual experiments	performed and evaluated individual experiments	Performed the experiments	Investigation	YES
6396144	30737259	JFP	2	designed and supervised the study|wrote the manuscript with contributions from all the authors	designed and supervised the study	Conceived and designed the experiments	Methodology|Supervision	YES
6396144	30737259	JFP	2	designed and supervised the study|wrote the manuscript with contributions from all the authors	wrote the manuscript with contributions from all the authors	Wrote the paper	Writing - Original Draft	YES
6396144	30737259	JLK	2	designed and supervised individual experiments	designed and supervised individual experiments	Conceived and designed the experiments	Methodology|Supervision	YES
6396144	30737259	JM	2	performed and evaluated individual experiments|designed and supervised individual experiments	performed and evaluated individual experiments	Performed the experiments	Investigation	YES
6396144	30737259	JM	2	performed and evaluated individual experiments|designed and supervised individual experiments	designed and supervised individual experiments	Conceived and designed the experiments	Methodology|Supervision	YES
6396144	30737259	JM-P	2	designed and supervised the study	designed and supervised the study	Conceived and designed the experiments	Methodology|Supervision	YES
6396144	30737259	KLK	2	performed and evaluated individual experiments	performed and evaluated individual experiments	Performed the experiments	Investigation	YES
6396144	30737259	LG	2	designed and supervised individual experiments|provided materials	designed and supervised individual experiments	Conceived and designed the experiments	Methodology|Supervision	YES
6396144	30737259	LG	2	designed and supervised individual experiments|provided materials	provided materials	Contributed reagents/materials/analysis tools	Resources	YES
6396144	30737259	MJS	2	performed and evaluated individual experiments	performed and evaluated individual experiments	Performed the experiments	Investigation	YES
6396144	30737259	MO	2	performed and evaluated individual experiments	performed and evaluated individual experiments	Performed the experiments	Investigation	YES
6396144	30737259	NKLB	2	designed and supervised individual experiments	designed and supervised individual experiments	Conceived and designed the experiments	Methodology|Supervision	YES
6396144	30737259	NR	2	performed and evaluated individual experiments	performed and evaluated individual experiments	Performed the experiments	Investigation	YES
6396144	30737259	PDA	2	designed and supervised individual experiments	designed and supervised individual experiments	Conceived and designed the experiments	Methodology|Supervision	YES
6396144	30737259	RA	2	performed the majority of experiments|wrote the manuscript with contributions from all the authors	performed the majority of experiments	Performed the experiments	Investigation	YES
6396144	30737259	RA	2	performed the majority of experiments|wrote the manuscript with contributions from all the authors	wrote the manuscript with contributions from all the authors	Wrote the paper	Writing - Original Draft	YES
6396144	30737259	RB-P	2	performed and evaluated individual experiments	performed and evaluated individual experiments	Performed the experiments	Investigation	YES
6396144	30737259	ST-C	2	performed and evaluated individual experiments	performed and evaluated individual experiments	Performed the experiments	Investigation	YES
6396144	30737259	SV	2	performed and evaluated individual experiments	performed and evaluated individual experiments	Performed the experiments	Investigation	YES
6396144	30737259	TT	2	performed and evaluated individual experiments	performed and evaluated individual experiments	Performed the experiments	Investigation	YES
6396144	30737259	VD-E	2	performed and evaluated individual experiments	performed and evaluated individual experiments	Performed the experiments	Investigation	YES
4416903	25932637	BS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416903	25932637	CC	PLoS5	Contributed to data interpretation and manuscript revision	Contributed to data interpretation and manuscript revision	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4416903	25932637	ET	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416903	25932637	GG	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416903	25932637	GK	PLoS5	Contributed to data interpretation and manuscript revision	Contributed to data interpretation and manuscript revision	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4416903	25932637	LS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416903	25932637	MB	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416903	25932637	MB	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416903	25932637	MC	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416903	25932637	MT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416903	25932637	MT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416903	25932637	MT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416903	25932637	MT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270747	24972273	A. Froystein	2	supervised the experiments and contributed to the paper	supervised the experiments and contributed to the paper	-	Supervision	YES
6270747	24972273	K. Brenner	2	designed the research, conducted the experiments, analyzed the data and prepared the manuscript	designed the research, conducted the experiments, analyzed the data and prepared the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5764018	29320989	HX	PLoS5	Wrote the paper|Critically revised the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5764018	29320989	HX	PLoS5	Wrote the paper|Critically revised the manuscript	Critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5764018	29320989	JL	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5764018	29320989	JL	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5764018	29320989	JQ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5764018	29320989	LG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5764018	29320989	MZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5764018	29320989	NR	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
5764018	29320989	NR	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5764018	29320989	NR	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5764018	29320989	RS	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5764018	29320989	RW	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5764018	29320989	YX	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5764018	29320989	YZ	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5764018	29320989	ZL	PLoS5	Analyzed the data|Wrote the paper|Critically revised the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
5764018	29320989	ZL	PLoS5	Analyzed the data|Wrote the paper|Critically revised the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5764018	29320989	ZL	PLoS5	Analyzed the data|Wrote the paper|Critically revised the manuscript	Critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5810273	29472935	BR	2	wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
5810273	29472935	DL	2	wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
5810273	29472935	TR	2	designed and wrote the article	designed and wrote the article	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
1976558	17895963	AB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Coordinated the study	Analyzed the data	Analyzed the data	Formal analysis	YES
1976558	17895963	AB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Coordinated the study	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1976558	17895963	AB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Coordinated the study	Coordinated the study	-	Project administration	YES
1976558	17895963	CC	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1976558	17895963	CC	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1976558	17895963	FG	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1976558	17895963	FG	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1976558	17895963	LP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Coordinated the study	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1976558	17895963	LP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Coordinated the study	Analyzed the data	Analyzed the data	Formal analysis	YES
1976558	17895963	LP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Coordinated the study	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1976558	17895963	LP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Coordinated the study	Coordinated the study	-	Project administration	YES
1976558	17895963	LS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1976558	17895963	LS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1976558	17895963	MB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1976558	17895963	MB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1976558	17895963	MB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5741567	29273963	All authors	2	were involved in the design of the study|read and approved the final manuscript	were involved in the design of the study	Conceived and designed the experiments	Methodology	YES
5741567	29273963	All authors	2	were involved in the design of the study|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5741567	29273963	The authors	2	contributed as follows|declare that they have no competing interests	contributed as follows	-	-	NO
5741567	29273963	The authors	2	contributed as follows|declare that they have no competing interests	declare that they have no competing interests	-	-	NO
4992714	27528780	All authors	2	were involved in developing the scope and preparing the contents of the paper|gave final approval for publication	were involved in developing the scope and preparing the contents of the paper	Wrote the paper	Writing - Original Draft	YES
4992714	27528780	All authors	2	were involved in developing the scope and preparing the contents of the paper|gave final approval for publication	gave final approval for publication	-	-	NO
4416904	25933100	GS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416904	25933100	GS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416904	25933100	GS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416904	25933100	JL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416904	25933100	JZ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416904	25933100	WB	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416904	25933100	WQ	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4416904	25933100	WQ	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416904	25933100	WR	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416904	25933100	YZ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416905	25933189	AAR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416905	25933189	AAR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416905	25933189	AAR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416905	25933189	AAR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416905	25933189	AASB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416905	25933189	ADL	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416905	25933189	BJGAA	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416905	25933189	BJGAA	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416905	25933189	BJGAA	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416905	25933189	CESM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4416905	25933189	CESM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416905	25933189	DESM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416905	25933189	FSS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4416905	25933189	FSS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416905	25933189	GO	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416905	25933189	JFB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416905	25933189	KSCS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416905	25933189	LAR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416905	25933189	LAR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416905	25933189	LAR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416905	25933189	LAR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416905	25933189	MAGU	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416905	25933189	MAGU	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416905	25933189	MBL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416905	25933189	MGA	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416905	25933189	MVLF	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416905	25933189	RHB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416905	25933189	RHB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416905	25933189	RHB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416905	25933189	RHB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416905	25933189	VMGDML	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
6396373	30696688	AK	CRediT	Investigation|Writing--review & editing|Resources	Investigation	Performed the experiments	Investigation	YES
6396373	30696688	AK	CRediT	Investigation|Writing--review & editing|Resources	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6396373	30696688	AK	CRediT	Investigation|Writing--review & editing|Resources	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6396373	30696688	BC	CRediT	Conceptualization|Methodology|Investigation|Writing--original draft|Writing--review & editing|Supervision	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6396373	30696688	BC	CRediT	Conceptualization|Methodology|Investigation|Writing--original draft|Writing--review & editing|Supervision	Methodology	Performed the experiments	Methodology	YES
6396373	30696688	BC	CRediT	Conceptualization|Methodology|Investigation|Writing--original draft|Writing--review & editing|Supervision	Investigation	Performed the experiments	Investigation	YES
6396373	30696688	BC	CRediT	Conceptualization|Methodology|Investigation|Writing--original draft|Writing--review & editing|Supervision	Writing--original draft	Wrote the paper	Writing - Original Draft	YES
6396373	30696688	BC	CRediT	Conceptualization|Methodology|Investigation|Writing--original draft|Writing--review & editing|Supervision	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6396373	30696688	BC	CRediT	Conceptualization|Methodology|Investigation|Writing--original draft|Writing--review & editing|Supervision	Supervision	-	Supervision	YES
6396373	30696688	JH	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
6396373	30696688	MMB	CRediT	Conceptualization|Writing--original draft|Funding acquisition|Resources|Supervision	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6396373	30696688	MMB	CRediT	Conceptualization|Writing--original draft|Funding acquisition|Resources|Supervision	Writing--original draft	Wrote the paper	Writing - Original Draft	YES
6396373	30696688	MMB	CRediT	Conceptualization|Writing--original draft|Funding acquisition|Resources|Supervision	Funding acquisition	-	Funding acquisition	YES
6396373	30696688	MMB	CRediT	Conceptualization|Writing--original draft|Funding acquisition|Resources|Supervision	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6396373	30696688	MMB	CRediT	Conceptualization|Writing--original draft|Funding acquisition|Resources|Supervision	Supervision	-	Supervision	YES
6396373	30696688	MS	CRediT	Conceptualization|Methodology|Investigation|Writing--original draft|Writing--review & editing|Supervision	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6396373	30696688	MS	CRediT	Conceptualization|Methodology|Investigation|Writing--original draft|Writing--review & editing|Supervision	Methodology	Performed the experiments	Methodology	YES
6396373	30696688	MS	CRediT	Conceptualization|Methodology|Investigation|Writing--original draft|Writing--review & editing|Supervision	Investigation	Performed the experiments	Investigation	YES
6396373	30696688	MS	CRediT	Conceptualization|Methodology|Investigation|Writing--original draft|Writing--review & editing|Supervision	Writing--original draft	Wrote the paper	Writing - Original Draft	YES
6396373	30696688	MS	CRediT	Conceptualization|Methodology|Investigation|Writing--original draft|Writing--review & editing|Supervision	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6396373	30696688	MS	CRediT	Conceptualization|Methodology|Investigation|Writing--original draft|Writing--review & editing|Supervision	Supervision	-	Supervision	YES
6396373	30696688	NAWL	CRediT	Methodology|Resources	Methodology	Performed the experiments	Methodology	YES
6396373	30696688	NAWL	CRediT	Methodology|Resources	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6396373	30696688	NF	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
6396373	30696688	SRP	CRediT	Resources	Resources	Contributed reagents/materials/analysis tools	Resources	YES
6396373	30696688	VJL	CRediT	Investigation|Writing--review & editing|Resources	Investigation	Performed the experiments	Investigation	YES
6396373	30696688	VJL	CRediT	Investigation|Writing--review & editing|Resources	Writing--review & editing	Wrote the paper	Writing - Review & Editing	YES
6396373	30696688	VJL	CRediT	Investigation|Writing--review & editing|Resources	Resources	Contributed reagents/materials/analysis tools	Resources	YES
5741568	29273919	AC	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5741568	29273919	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5741568	29273919	CD-C	PLoS52	conceived and designed the study|performed the experiments|wrote the paper	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5741568	29273919	CD-C	PLoS52	conceived and designed the study|performed the experiments|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5741568	29273919	CD-C	PLoS52	conceived and designed the study|performed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5741568	29273919	FAR	PLoS52	reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5741568	29273919	JR	PLoS52	reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5741568	29273919	LYR	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5741568	29273919	MMZ	PLoS52	conceived and designed the study|reviewed and edited the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5741568	29273919	MMZ	PLoS52	conceived and designed the study|reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5741568	29273919	SB	PLoS52	conceived and designed the study|wrote the paper	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5741568	29273919	SB	PLoS52	conceived and designed the study|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5741568	29273919	SF	PLoS52	conceived and designed the study|reviewed and edited the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5741568	29273919	SF	PLoS52	conceived and designed the study|reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5741568	29273919	TS	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5810296	29472938	AN	2	performed the modeling work	performed the modeling work	Performed the experiments	Investigation|Methodology	YES
5810296	29472938	All authors	2	wrote and edited the manuscript	wrote and edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5810296	29472938	HH	2	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5810296	29472938	JC	2	performed the experimental work	performed the experimental work	Performed the experiments	Investigation	YES
5810296	29472938	QY	2	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5810296	29472938	SP	2	supervised the research and manuscript preparation	supervised the research and manuscript preparation	Wrote the paper	Supervision|Writing - Original Draft	YES
5810296	29472938	ZC	2	designed the experiments|performed the experimental work	designed the experiments	Conceived and designed the experiments	Methodology	YES
5810296	29472938	ZC	2	designed the experiments|performed the experimental work	performed the experimental work	Performed the experiments	Investigation	YES
6270749	24936706	FZ	PLoS5	Prepared neuromelanin samples	Prepared neuromelanin samples	Performed the experiments	Investigation	YES
6270749	24936706	HT	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
6270749	24936706	HT	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
6270749	24936706	KT	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
6270749	24936706	KT	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
6270749	24936706	KW	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6270749	24936706	KW	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270749	24936706	LZ	PLoS5	Prepared neuromelanin samples	Prepared neuromelanin samples	Performed the experiments	Investigation	YES
6270749	24936706	MO	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
6270749	24936706	SI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6270749	24936706	SI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
6270749	24936706	SI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
6270749	24936706	SI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1976559	17895964	CL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1976559	17895964	EH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1976559	17895964	EH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1976559	17895964	EH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1976559	17895964	JR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1976559	17895964	JR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1976559	17895964	JR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1976559	17895964	JR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1976559	17895964	LM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1976559	17895964	LM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1976559	17895964	LM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4992716	27528782	A.M.R.	2	conceived and developed the new turbulent jerks hypothesis for insect orientation at altitude, and all authors contributed to writing the review	conceived and developed the new turbulent jerks hypothesis for insect orientation at altitude, and all authors contributed to writing the review	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
4992716	27528782	J.W.C.	2	conceived the review	conceived the review	Conceived and designed the experiments	Conceptualization	YES
5764023	29320982	HC	PLoS52	carried out computational analysis, microarray and rna seq expression profiling|wrote the manuscript	carried out computational analysis, microarray and rna seq expression profiling	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5764023	29320982	HC	PLoS52	carried out computational analysis, microarray and rna seq expression profiling|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5764023	29320982	KW	PLoS52	conceptualized, designed the project|performed the experiments|wrote the manuscript	conceptualized, designed the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5764023	29320982	KW	PLoS52	conceptualized, designed the project|performed the experiments|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5764023	29320982	KW	PLoS52	conceptualized, designed the project|performed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4416906	25932642	HG	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4416906	25932642	HG	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4416906	25932642	HG	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416906	25932642	JP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416906	25932642	JP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416906	25932642	JP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416906	25932642	JP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416906	25932642	PW	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4416906	25932642	PW	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416906	25932642	XJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416906	25932642	XJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416906	25932642	XJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416906	25932642	XQ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416906	25932642	XQ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416906	25932642	XQ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3284236	22297440	all authors	2	contributed equally and approve the final version	contributed equally and approve the final version	-	-	NO
4637071	26583135	Chiara Corrado	2	contributed equally to this work	contributed equally to this work	-	-	NO
4637071	26583135	Stefania Raimondo	2	contributed equally to this work	contributed equally to this work	-	-	NO
4992718	27528784	All authors	2	gave final approval for publication	gave final approval for publication	-	-	NO
4992718	27528784	C.W.	2	were responsible for critical revisions of the manuscript	were responsible for critical revisions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4992718	27528784	S.P.W.	2	were responsible for critical revisions of the manuscript	were responsible for critical revisions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4992718	27528784	all authors	2	were responsible for critical revisions of the manuscript	were responsible for critical revisions of the manuscript	Wrote the paper	Writing - Review & Editing	YES
6270750	25068786	A. Al-Dhabi	2	wrote the manuscript, performed the experiments, and analyzed the data	wrote the manuscript, performed the experiments, and analyzed the data	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6270750	25068786	U. Park	2	designed the experiments and analyzed the data	designed the experiments and analyzed the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
1976560	17895986	GW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1976560	17895986	GW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1976560	17895986	GW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1976560	17895986	PB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1976560	17895986	PB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1976560	17895986	PB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1976560	17895986	PB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1976560	17895986	PB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1976560	17895986	RN	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1976560	17895986	YN	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1976560	17895986	ZK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1976560	17895986	ZK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1976560	17895986	ZK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1976560	17895986	ZK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5741572	29273952	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5741572	29273952	HAS	2	contributed to data analysis	contributed to data analysis	Analyzed the data	Formal analysis	YES
5741572	29273952	MA	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5741572	29273952	MHS	2	was the main investigator, synthesized the nanocomposite|drafted the manuscript	was the main investigator, synthesized the nanocomposite	Performed the experiments	Investigation	YES
5741572	29273952	MHS	2	was the main investigator, synthesized the nanocomposite|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5741572	29273952	SAM	2	contributed to data analysis	contributed to data analysis	Analyzed the data	Formal analysis	YES
6418418	30804002	MJK	2	performed most experiments|analysed mass spectrometry results|designed experiments|wrote the manuscript with input from all authors	performed most experiments	Performed the experiments	Investigation	YES
6418418	30804002	MJK	2	performed most experiments|analysed mass spectrometry results|designed experiments|wrote the manuscript with input from all authors	analysed mass spectrometry results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6418418	30804002	MJK	2	performed most experiments|analysed mass spectrometry results|designed experiments|wrote the manuscript with input from all authors	designed experiments	Conceived and designed the experiments	Methodology	YES
6418418	30804002	MJK	2	performed most experiments|analysed mass spectrometry results|designed experiments|wrote the manuscript with input from all authors	wrote the manuscript with input from all authors	Wrote the paper	Writing - Original Draft	YES
6418418	30804002	MT	2	analysed mass spectrometry results	analysed mass spectrometry results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6418418	30804002	RB	2	performed 2d gel electrophoresis	performed 2d gel electrophoresis	Performed the experiments	Investigation	YES
6418418	30804002	RG	2	processed mass spectrometry samples and performed database searches|analysed mass spectrometry results	processed mass spectrometry samples and performed database searches	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Investigation|Software	YES
6418418	30804002	RG	2	processed mass spectrometry samples and performed database searches|analysed mass spectrometry results	analysed mass spectrometry results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6418418	30804002	RH	2	designed nedp1 constructs, performed halo-nedp1 pulldowns and sample preparation for the hek 293 mass spectrometry experiment and performed some cell viability experiments|analysed mass spectrometry results|designed experiments	designed nedp1 constructs, performed halo-nedp1 pulldowns and sample preparation for the hek 293 mass spectrometry experiment and performed some cell viability experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6418418	30804002	RH	2	designed nedp1 constructs, performed halo-nedp1 pulldowns and sample preparation for the hek 293 mass spectrometry experiment and performed some cell viability experiments|analysed mass spectrometry results|designed experiments	analysed mass spectrometry results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6418418	30804002	RH	2	designed nedp1 constructs, performed halo-nedp1 pulldowns and sample preparation for the hek 293 mass spectrometry experiment and performed some cell viability experiments|analysed mass spectrometry results|designed experiments	designed experiments	Conceived and designed the experiments	Methodology	YES
6418418	30804002	TK	2	analysed mass spectrometry results|designed experiments|wrote the manuscript with input from all authors|supervised the work	analysed mass spectrometry results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6418418	30804002	TK	2	analysed mass spectrometry results|designed experiments|wrote the manuscript with input from all authors|supervised the work	designed experiments	Conceived and designed the experiments	Methodology	YES
6418418	30804002	TK	2	analysed mass spectrometry results|designed experiments|wrote the manuscript with input from all authors|supervised the work	wrote the manuscript with input from all authors	Wrote the paper	Writing - Original Draft	YES
6418418	30804002	TK	2	analysed mass spectrometry results|designed experiments|wrote the manuscript with input from all authors|supervised the work	supervised the work	-	Supervision	YES
5811460	29479367	FZ	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5811460	29479367	X-RC	2	collected the data and the references	collected the data and the references	Performed the experiments	Investigation	YES
5811460	29479367	Y-KZ	2	collected the data and the references	collected the data and the references	Performed the experiments	Investigation	YES
5811460	29479367	Z-LJ	2	collected the data and the references	collected the data and the references	Performed the experiments	Investigation	YES
4416907	25933005	CT	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416907	25933005	EN	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416907	25933005	GK	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416907	25933005	HG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4416907	25933005	HG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416907	25933005	PG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416907	25933005	PG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416907	25933005	PG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416907	25933005	PG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416907	25933005	VD	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416907	25933005	VV	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416907	25933005	VV	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416907	25933005	WB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416907	25933005	WB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416907	25933005	WB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416907	25933005	WB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5767027	29329522	AP	2	contributed to the design of the workflows, tested the web interface and wrote the manuscript	contributed to the design of the workflows, tested the web interface and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Methodology|Software|Writing - Original Draft	YES
5767027	29329522	DSH	2	conceived the study, performed comparative analyses, tested the web interface and wrote the manuscript	conceived the study, performed comparative analyses, tested the web interface and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Software|Writing - Original Draft	YES
5767027	29329522	EP	2	tested the web interface and wrote the manuscript	tested the web interface and wrote the manuscript	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Software|Writing - Original Draft	YES
5767027	29329522	GP	2	conceived the study, tested the web interface and wrote the manuscript	conceived the study, tested the web interface and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Investigation|Software|Writing - Original Draft	YES
5767027	29329522	LC	2	conceived the study, tested the web interface and wrote the manuscript	conceived the study, tested the web interface and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Investigation|Software|Writing - Original Draft	YES
5767027	29329522	MC	2	implemented the software, performed comparative analyses and wrote the manuscript	implemented the software, performed comparative analyses and wrote the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Software|Writing - Original Draft	YES
4992722	27528788	G.K.T.	2	conceived the study, derived the theory, supervised the experiments, analysed the data, prepared the figures and wrote the paper|improved the final draft of the paper	conceived the study, derived the theory, supervised the experiments, analysed the data, prepared the figures and wrote the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Supervision|Visualization|Writing - Original Draft	YES
4992722	27528788	G.K.T.	2	conceived the study, derived the theory, supervised the experiments, analysed the data, prepared the figures and wrote the paper|improved the final draft of the paper	improved the final draft of the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4992722	27528788	K.V.R.	2	undertook the experiments, analysed data, contributed figures and approved the final draft of the paper	undertook the experiments, analysed data, contributed figures and approved the final draft of the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Visualization|Writing - Original Draft	YES
1976591	17895983	AR	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1976591	17895983	AW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1976591	17895983	AW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1976591	17895983	AW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1976591	17895983	AW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1976591	17895983	CS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1976591	17895983	MP	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1976591	17895983	NH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1976591	17895983	SA	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1976591	17895983	SB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1976591	17895983	SB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1976591	17895983	YS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416908	25933203	AA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416908	25933203	AA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416908	25933203	AA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416908	25933203	AA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416908	25933203	AB	PLoS5	Contributed reagents/materials/analysis tools|Major criticism of the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416908	25933203	AB	PLoS5	Contributed reagents/materials/analysis tools|Major criticism of the manuscript	Major criticism of the manuscript	-	-	NO
4416908	25933203	ER	PLoS5	Contributed reagents/materials/analysis tools|Major criticism of the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416908	25933203	ER	PLoS5	Contributed reagents/materials/analysis tools|Major criticism of the manuscript	Major criticism of the manuscript	-	-	NO
4416908	25933203	JM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416908	25933203	JMM	PLoS5	Contributed reagents/materials/analysis tools|Major criticism of the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416908	25933203	JMM	PLoS5	Contributed reagents/materials/analysis tools|Major criticism of the manuscript	Major criticism of the manuscript	-	-	NO
4416908	25933203	MGM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416908	25933203	MGM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416908	25933203	MGM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416908	25933203	MGM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416908	25933203	MNP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4416908	25933203	MNP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416908	25933203	NDC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4416908	25933203	NDC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416908	25933203	NG	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416908	25933203	SB	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416908	25933203	SB	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416908	25933203	SV	PLoS5	Contributed reagents/materials/analysis tools|Major criticism of the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416908	25933203	SV	PLoS5	Contributed reagents/materials/analysis tools|Major criticism of the manuscript	Major criticism of the manuscript	-	-	NO
4416908	25933203	VD	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4416908	25933203	VD	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5811478	29479359	CW	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5811478	29479359	HH	2	participated in the growing of transgenic rice	participated in the growing of transgenic rice	Performed the experiments	Investigation	YES
5811478	29479359	LY	2	designed the study|conceived the project and wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5811478	29479359	LY	2	designed the study|conceived the project and wrote the manuscript	conceived the project and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5811478	29479359	MS	2	assisted in conducting the experiments, especially prokaryotic expression	assisted in conducting the experiments, especially prokaryotic expression	Performed the experiments	Investigation	YES
5811478	29479359	WZ	2	performed the bioinformatic analyses	performed the bioinformatic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5811478	29479359	XN	2	carried out vector construction, rice transformation and phenotype assays experiments	carried out vector construction, rice transformation and phenotype assays experiments	Performed the experiments	Investigation	YES
5811478	29479359	YS	2	participated in the subcellular localization and histochemical experiments	participated in the subcellular localization and histochemical experiments	Performed the experiments	Investigation	YES
6418429	30609993	All authors	2	jointly interpreted the data and thoroughly checked the manuscript	jointly interpreted the data and thoroughly checked the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
6418429	30609993	JLB	2	designed the project|wrote the manuscript	designed the project	Conceived and designed the experiments	Methodology	YES
6418429	30609993	JLB	2	designed the project|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6418429	30609993	KN	2	performed experiments and/or omics data analyses|designed the project|wrote the manuscript	performed experiments and/or omics data analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6418429	30609993	KN	2	performed experiments and/or omics data analyses|designed the project|wrote the manuscript	designed the project	Conceived and designed the experiments	Methodology	YES
6418429	30609993	KN	2	performed experiments and/or omics data analyses|designed the project|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6418429	30609993	KO	2	performed experiments and/or omics data analyses|designed the project	performed experiments and/or omics data analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6418429	30609993	KO	2	performed experiments and/or omics data analyses|designed the project	designed the project	Conceived and designed the experiments	Methodology	YES
6418429	30609993	KTY	2	performed experiments and/or omics data analyses|designed the project	performed experiments and/or omics data analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6418429	30609993	KTY	2	performed experiments and/or omics data analyses|designed the project	designed the project	Conceived and designed the experiments	Methodology	YES
6418429	30609993	MS	2	performed experiments and/or omics data analyses	performed experiments and/or omics data analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6418429	30609993	RN	2	designed the project	designed the project	Conceived and designed the experiments	Methodology	YES
6418429	30609993	SY	2	performed experiments and/or omics data analyses|designed the project	performed experiments and/or omics data analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6418429	30609993	SY	2	performed experiments and/or omics data analyses|designed the project	designed the project	Conceived and designed the experiments	Methodology	YES
6418429	30609993	TH	2	performed experiments and/or omics data analyses|designed the project|wrote the manuscript	performed experiments and/or omics data analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6418429	30609993	TH	2	performed experiments and/or omics data analyses|designed the project|wrote the manuscript	designed the project	Conceived and designed the experiments	Methodology	YES
6418429	30609993	TH	2	performed experiments and/or omics data analyses|designed the project|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6418429	30609993	TKa	2	performed experiments and/or omics data analyses	performed experiments and/or omics data analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6418429	30609993	TKo	2	designed the project	designed the project	Conceived and designed the experiments	Methodology	YES
5742092	29275520	All	PLoS52	the relevant data and materials are presented in the manuscript	the relevant data and materials are presented in the manuscript	-	-	NO
5742092	29275520	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5742092	29275520	CW	PLoS52	performed experiment and data analysis	performed experiment and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5742092	29275520	MS	PLoS52	helped with the dgge analysis|wrote the paper	helped with the dgge analysis	-	-	NO
5742092	29275520	MS	PLoS52	helped with the dgge analysis|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5742092	29275520	QZ	PLoS52	developed the idea|performed experiment and data analysis|wrote the paper	developed the idea	Conceived and designed the experiments	Conceptualization	YES
5742092	29275520	QZ	PLoS52	developed the idea|performed experiment and data analysis|wrote the paper	performed experiment and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5742092	29275520	QZ	PLoS52	developed the idea|performed experiment and data analysis|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5742092	29275520	The authors	PLoS52	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5767043	29329517	HJ	2	wrote the manuscripts	wrote the manuscripts	Wrote the paper	Writing - Original Draft	YES
5767043	29329517	J-KK	2	conceived the research plans|wrote the manuscripts	conceived the research plans	Conceived and designed the experiments	Conceptualization	YES
5767043	29329517	J-KK	2	conceived the research plans|wrote the manuscripts	wrote the manuscripts	Wrote the paper	Writing - Original Draft	YES
5767043	29329517	OsNAC	2	transgenic plants and performed western blot analysis	transgenic plants and performed western blot analysis	Performed the experiments	Investigation	YES
5767043	29329517	PJC	2	conceived the research plans|performed the molecular experiments and analyses chip-seq and rna seq|wrote the manuscripts	conceived the research plans	Conceived and designed the experiments	Conceptualization	YES
5767043	29329517	PJC	2	conceived the research plans|performed the molecular experiments and analyses chip-seq and rna seq|wrote the manuscripts	performed the molecular experiments and analyses chip-seq and rna seq	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5767043	29329517	PJC	2	conceived the research plans|performed the molecular experiments and analyses chip-seq and rna seq|wrote the manuscripts	wrote the manuscripts	Wrote the paper	Writing - Original Draft	YES
5767043	29329517	YDC	2	wrote the manuscripts	wrote the manuscripts	Wrote the paper	Writing - Original Draft	YES
6270752	25412048	All authors	2	discussed the results and commented on the manuscript	discussed the results and commented on the manuscript	-	-	NO
6270752	25412048	Jinying Lv	2	performed the experiment	performed the experiment	Performed the experiments	Investigation	YES
6270752	25412048	Lixin Zhang	2	performed the experiment	performed the experiment	Performed the experiments	Investigation	YES
6270752	25412048	Min Mao	2	performed the experiment	performed the experiment	Performed the experiments	Investigation	YES
6270752	25412048	Qian Li	2	designed the experiments|performed the experiment	designed the experiments	Conceived and designed the experiments	Methodology	YES
6270752	25412048	Qian Li	2	designed the experiments|performed the experiment	performed the experiment	Performed the experiments	Investigation	YES
6270752	25412048	Shuzhen Li	2	performed the experiment	performed the experiment	Performed the experiments	Investigation	YES
6270752	25412048	Xia Li	2	performed the experiment	performed the experiment	Performed the experiments	Investigation	YES
6270752	25412048	Xiaodong Zheng	2	designed the experiments|revised the paper	designed the experiments	Conceived and designed the experiments	Methodology	YES
6270752	25412048	Xiaodong Zheng	2	designed the experiments|revised the paper	revised the paper	Wrote the paper	Writing - Review & Editing	YES
6270752	25412048	Yanli Qiu	2	performed the experiment	performed the experiment	Performed the experiments	Investigation	YES
1976594	17895985	HK	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1976594	17895985	HK	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1976594	17895985	IO	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1976594	17895985	IO	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1976594	17895985	MP	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1976594	17895985	MP	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1976594	17895985	MT	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1976594	17895985	MT	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1976594	17895985	MT	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1976594	17895985	SK	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1976594	17895985	SK	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1976594	17895985	SK	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1976594	17895985	TT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1976594	17895985	TT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1976594	17895985	TT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1976594	17895985	TT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1976594	17895985	YK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1976594	17895985	YK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1976594	17895985	YK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1976594	17895985	YK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1976594	17895985	YK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416909	25932646	LP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416909	25932646	LP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416909	25932646	LP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416909	25932646	LP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416909	25932646	PW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416909	25932646	PW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416909	25932646	PW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416909	25932646	PW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5767969	29334896	CAD	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
5767969	29334896	CWJ	PLoS52	designed research|performed research|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
5767969	29334896	CWJ	PLoS52	designed research|performed research|wrote the paper	performed research	Performed the experiments	Investigation	YES
5767969	29334896	CWJ	PLoS52	designed research|performed research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5767969	29334896	MAS	PLoS52	designed research|performed research|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
5767969	29334896	MAS	PLoS52	designed research|performed research|wrote the paper	performed research	Performed the experiments	Investigation	YES
5767969	29334896	MAS	PLoS52	designed research|performed research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5767969	29334896	NAM	PLoS52	designed research|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
5767969	29334896	NAM	PLoS52	designed research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5767969	29334896	NJM	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
5811519	29479360	ID	1	Conceived and designed the research|Contributed to the paper and revised it critically for important intellectual content	Conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5811519	29479360	ID	1	Conceived and designed the research|Contributed to the paper and revised it critically for important intellectual content	Contributed to the paper and revised it critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5811519	29479360	LP	1	Contributed to the paper and revised it critically for important intellectual content	Contributed to the paper and revised it critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5811519	29479360	MM	1	Conceived and designed the research|Contributed to the paper and revised it critically for important intellectual content	Conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5811519	29479360	MM	1	Conceived and designed the research|Contributed to the paper and revised it critically for important intellectual content	Contributed to the paper and revised it critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5811519	29479360	NL	1	Contributed to the paper and revised it critically for important intellectual content	Contributed to the paper and revised it critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5811519	29479360	NM	1	Contributed to the paper and revised it critically for important intellectual content	Contributed to the paper and revised it critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5003854	27574306	K.T.K.	PLoS52	critically edited the paper|collected the fscv data|analysed the data	critically edited the paper	Wrote the paper	Writing - Review & Editing	YES
5003854	27574306	K.T.K.	PLoS52	critically edited the paper|collected the fscv data|analysed the data	collected the fscv data	Performed the experiments	Investigation	YES
5003854	27574306	K.T.K.	PLoS52	critically edited the paper|collected the fscv data|analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
5003854	27574306	P.R.M.	PLoS52	designed the task|wrote the paper|analysed the data	designed the task	Conceived and designed the experiments	-	YES
5003854	27574306	P.R.M.	PLoS52	designed the task|wrote the paper|analysed the data	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5003854	27574306	P.R.M.	PLoS52	designed the task|wrote the paper|analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
5003854	27574306	T.L.	PLoS52	designed the task|wrote the paper|analysed the data	designed the task	Conceived and designed the experiments	-	YES
5003854	27574306	T.L.	PLoS52	designed the task|wrote the paper|analysed the data	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5003854	27574306	T.L.	PLoS52	designed the task|wrote the paper|analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
1976595	17895965	AC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1976595	17895965	AC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1976595	17895965	AC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1976595	17895965	AC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1976595	17895965	AP	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1976595	17895965	AP	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1976595	17895965	AT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1976595	17895965	AT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1976595	17895965	AT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1976595	17895965	AT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1976595	17895965	AT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1976595	17895965	CO	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Critical reading of the manuscript|Grammar revision	Analyzed the data	Analyzed the data	Formal analysis	YES
1976595	17895965	CO	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Critical reading of the manuscript|Grammar revision	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1976595	17895965	CO	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Critical reading of the manuscript|Grammar revision	Critical reading of the manuscript	-	-	NO
1976595	17895965	CO	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Critical reading of the manuscript|Grammar revision	Grammar revision	Wrote the paper	Writing - Review & Editing	YES
1976595	17895965	CS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1976595	17895965	CS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1976595	17895965	KL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1976595	17895965	MJ	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1976595	17895965	MJ	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
3284240	22297444	AJLM	2	data analysis and interpretation contribution, final manuscript writing	data analysis and interpretation contribution, final manuscript writing	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
3284240	22297444	AM	2	histopathological diagnosis for ulcerative colitis performing	histopathological diagnosis for ulcerative colitis performing	Performed the experiments	Investigation	YES
3284240	22297444	CS	2	patients selection and endoscopy examination and tissue biopsy performing|final approval of the manuscript publishing version|contributed equally to the present work	patients selection and endoscopy examination and tissue biopsy performing	Performed the experiments	Investigation	YES
3284240	22297444	CS	2	patients selection and endoscopy examination and tissue biopsy performing|final approval of the manuscript publishing version|contributed equally to the present work	final approval of the manuscript publishing version	-	-	NO
3284240	22297444	CS	2	patients selection and endoscopy examination and tissue biopsy performing|final approval of the manuscript publishing version|contributed equally to the present work	contributed equally to the present work	-	-	NO
3284240	22297444	ECdM	2	data analysis and interpretation contribution, final manuscript writing	data analysis and interpretation contribution, final manuscript writing	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
3284240	22297444	FC	2	quantitative immunohistochemical analysis of all samples performing|data analysis and interpretation contribution, article drafting	quantitative immunohistochemical analysis of all samples performing	Performed the experiments	Investigation	YES
3284240	22297444	FC	2	quantitative immunohistochemical analysis of all samples performing|data analysis and interpretation contribution, article drafting	data analysis and interpretation contribution, article drafting	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3284240	22297444	FF	2	study conception and design|quantitative immunohistochemical analysis of all samples performing	study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
3284240	22297444	FF	2	study conception and design|quantitative immunohistochemical analysis of all samples performing	quantitative immunohistochemical analysis of all samples performing	Performed the experiments	Investigation	YES
3284240	22297444	FMA	2	statistical analyses	statistical analyses	Analyzed the data	Formal analysis	YES
3284240	22297444	FR	2	tissue preparation and immunohistochemistry performing|quantitative immunohistochemical analysis of all samples performing	tissue preparation and immunohistochemistry performing	Performed the experiments	Investigation	YES
3284240	22297444	FR	2	tissue preparation and immunohistochemistry performing|quantitative immunohistochemical analysis of all samples performing	quantitative immunohistochemical analysis of all samples performing	Performed the experiments	Investigation	YES
3284240	22297444	GC	2	study conception and design	study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
3284240	22297444	GM	2	study conception and design	study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
3284240	22297444	GT	2	study conception and design|patients selection and endoscopy examination and tissue biopsy performing|final approval of the manuscript publishing version|contributed equally to the present work	study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
3284240	22297444	GT	2	study conception and design|patients selection and endoscopy examination and tissue biopsy performing|final approval of the manuscript publishing version|contributed equally to the present work	patients selection and endoscopy examination and tissue biopsy performing	Performed the experiments	Investigation	YES
3284240	22297444	GT	2	study conception and design|patients selection and endoscopy examination and tissue biopsy performing|final approval of the manuscript publishing version|contributed equally to the present work	final approval of the manuscript publishing version	-	-	NO
3284240	22297444	GT	2	study conception and design|patients selection and endoscopy examination and tissue biopsy performing|final approval of the manuscript publishing version|contributed equally to the present work	contributed equally to the present work	-	-	NO
3284240	22297444	GZ	2	study conception and design	study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
3284240	22297444	MR	2	patients selection and endoscopy examination and tissue biopsy performing	patients selection and endoscopy examination and tissue biopsy performing	Performed the experiments	Investigation	YES
3284240	22297444	MZ	2	tissue preparation and immunohistochemistry performing	tissue preparation and immunohistochemistry performing	Performed the experiments	Investigation	YES
3284240	22297444	PD	2	data interpretation substantial contribution	data interpretation substantial contribution	Analyzed the data	Formal analysis	YES
3284240	22297444	RDL	2	data interpretation substantial contribution	data interpretation substantial contribution	Analyzed the data	Formal analysis	YES
3284240	22297444	VR	2	histopathological diagnosis for ulcerative colitis performing	histopathological diagnosis for ulcerative colitis performing	Performed the experiments	Investigation	YES
5754280	29302756	All authors	2	contributed equally in writing this review article|read and approved the final manuscript	contributed equally in writing this review article	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5754280	29302756	All authors	2	contributed equally in writing this review article|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5811523	29479362	AL	2	contributed to the review editing, writing and data evaluation	contributed to the review editing, writing and data evaluation	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Review & Editing	YES
5811523	29479362	MT	2	contributed to the review conception, literature analysis and writing	contributed to the review conception, literature analysis and writing	Conceived and designed the experiments|Wrote the paper	Conceptualization|Formal analysis	YES
5811523	29479362	NK	2	contributed to the review conception, literature analysis and writing	contributed to the review conception, literature analysis and writing	Conceived and designed the experiments|Wrote the paper	Conceptualization|Formal analysis	YES
5769328	29334893	HLA	2	typing scripts and performed data analysis|capture experiments, and wrote the manuscript	typing scripts and performed data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Software	YES
5769328	29334893	HLA	2	typing scripts and performed data analysis|capture experiments, and wrote the manuscript	capture experiments, and wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4416910	25932998	ML	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416910	25932998	ML	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416910	25932998	ML	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416910	25932998	QD	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416910	25932998	QD	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416910	25932998	QD	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416910	25932998	XJ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416910	25932998	XJ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416910	25932998	XJ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270754	25225723	A.W.	1	Important contributions to design and also to prepare the manuscript	Important contributions to design and also to prepare the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
6270754	25225723	J.O.	1	Important contributions to design and also to prepare the manuscript|Contributed to sample and analysis experiments|Analysis of the experimental data	Important contributions to design and also to prepare the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
6270754	25225723	J.O.	1	Important contributions to design and also to prepare the manuscript|Contributed to sample and analysis experiments|Analysis of the experimental data	Contributed to sample and analysis experiments	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
6270754	25225723	J.O.	1	Important contributions to design and also to prepare the manuscript|Contributed to sample and analysis experiments|Analysis of the experimental data	Analysis of the experimental data	Analyzed the data	Formal analysis	YES
6270754	25225723	S.K.	1	Contributed to sample and analysis experiments	Contributed to sample and analysis experiments	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
6418468	30643018	B. All	2	authors contributed to and approved the manuscript	authors contributed to and approved the manuscript	-	-	NO
6418468	30643018	FC	2	conceived the project, designed the experiments, interpreted the data and wrote the manuscript	conceived the project, designed the experiments, interpreted the data and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
6418468	30643018	SBA	2	conceived the project, designed the experiments, interpreted the data and wrote the manuscript	conceived the project, designed the experiments, interpreted the data and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
1976596	17895966	AM	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1976596	17895966	AM	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1976596	17895966	AS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1976596	17895966	DD	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1976596	17895966	DD	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1976596	17895966	DS	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1976596	17895966	DS	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1976596	17895966	JW	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1976596	17895966	JW	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1976596	17895966	KB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1976596	17895966	KD	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1976596	17895966	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1976596	17895966	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1976596	17895966	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1976596	17895966	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1976596	17895966	MQ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1976596	17895966	MR	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1976596	17895966	NI	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1976596	17895966	SM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1976596	17895966	WL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1976596	17895966	WL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5003856	27574308	All authors	2	contributed to the preparation of the manuscript and design of the figures	contributed to the preparation of the manuscript and design of the figures	Conceived and designed the experiments|Wrote the paper	Visualization|Writing - Original Draft	YES
3284241	22297445	FP	2	contributed equally to the manuscript	contributed equally to the manuscript	-	-	NO
3284241	22297445	MTI	2	contributed equally to the manuscript	contributed equally to the manuscript	-	-	NO
5811635	29479361	BB	2	planned and designed the research|performed the experiments and analyzed the data	planned and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5811635	29479361	BB	2	planned and designed the research|performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5811635	29479361	ES	2	performed the experiments and analyzed the data|wrote the manuscript	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5811635	29479361	ES	2	performed the experiments and analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5811635	29479361	IP	2	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5811635	29479361	UC	2	planned and designed the research|wrote the manuscript	planned and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5811635	29479361	UC	2	planned and designed the research|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5769345	29334898	All authors	2	contributed to preparation of the manuscript|reviewed and commented on the manuscript	contributed to preparation of the manuscript	Wrote the paper	Writing - Original Draft	YES
5769345	29334898	All authors	2	contributed to preparation of the manuscript|reviewed and commented on the manuscript	reviewed and commented on the manuscript	Wrote the paper	Writing - Review & Editing	YES
5769345	29334898	BYR	2	designed the workflow and experiments	designed the workflow and experiments	Conceived and designed the experiments|Performed the experiments	Methodology	YES
5769345	29334898	CJ	2	designed the workflow and experiments|wrote the software|executed the experiments	designed the workflow and experiments	Conceived and designed the experiments|Performed the experiments	Methodology	YES
5769345	29334898	CJ	2	designed the workflow and experiments|wrote the software|executed the experiments	wrote the software	Contributed reagents/materials/analysis tools|Wrote the paper	Software|Writing - Original Draft	YES
5769345	29334898	CJ	2	designed the workflow and experiments|wrote the software|executed the experiments	executed the experiments	Performed the experiments	Investigation	YES
5769345	29334898	PWD	2	designed the workflow and experiments|wrote the software	designed the workflow and experiments	Conceived and designed the experiments|Performed the experiments	Methodology	YES
5769345	29334898	PWD	2	designed the workflow and experiments|wrote the software	wrote the software	Contributed reagents/materials/analysis tools|Wrote the paper	Software|Writing - Original Draft	YES
5769345	29334898	SF	2	designed the workflow and experiments	designed the workflow and experiments	Conceived and designed the experiments|Performed the experiments	Methodology	YES
5758483	29313258	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5758483	29313258	All the authors	2	of this paper have collaborated on conducting experiments, analyzing the results, and writing the paper	of this paper have collaborated on conducting experiments, analyzing the results, and writing the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5758483	29313258	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
1976597	17895967	AC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1976597	17895967	AC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1976597	17895967	AC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1976597	17895967	AC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1976597	17895967	GD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1976597	17895967	GD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1976597	17895967	GD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1976597	17895967	GD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1976597	17895967	PC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1976597	17895967	PC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1976597	17895967	PC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1976597	17895967	PC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1976597	17895967	RO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1976597	17895967	RO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1976597	17895967	RO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1976597	17895967	RO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1976597	17895967	RO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1976597	17895967	SB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1976597	17895967	SB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1976597	17895967	SB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1976597	17895967	SB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416911	25933225	CV	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416911	25933225	CV	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416911	25933225	CV	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416911	25933225	EB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416911	25933225	LB	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416911	25933225	LB	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416911	25933225	LO	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416911	25933225	LO	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416911	25933225	LO	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416911	25933225	ML	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416911	25933225	ML	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416911	25933225	MN	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416911	25933225	MN	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6418696	30796049	AG	CRediT	Conceptualization|Validation|Formal analysis|Investigation|Writing|Visualization|Supervision	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6418696	30796049	AG	CRediT	Conceptualization|Validation|Formal analysis|Investigation|Writing|Visualization|Supervision	Validation	Performed the experiments	Validation	YES
6418696	30796049	AG	CRediT	Conceptualization|Validation|Formal analysis|Investigation|Writing|Visualization|Supervision	Formal analysis	Analyzed the data	Formal analysis	YES
6418696	30796049	AG	CRediT	Conceptualization|Validation|Formal analysis|Investigation|Writing|Visualization|Supervision	Investigation	Performed the experiments	Investigation	YES
6418696	30796049	AG	CRediT	Conceptualization|Validation|Formal analysis|Investigation|Writing|Visualization|Supervision	Writing	Wrote the paper	-	YES
6418696	30796049	AG	CRediT	Conceptualization|Validation|Formal analysis|Investigation|Writing|Visualization|Supervision	Visualization	Analyzed the data	Visualization	YES
6418696	30796049	AG	CRediT	Conceptualization|Validation|Formal analysis|Investigation|Writing|Visualization|Supervision	Supervision	-	Supervision	YES
6418696	30796049	AP	CRediT	Conceptualization|Validation|Formal analysis|Investigation	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6418696	30796049	AP	CRediT	Conceptualization|Validation|Formal analysis|Investigation	Validation	Performed the experiments	Validation	YES
6418696	30796049	AP	CRediT	Conceptualization|Validation|Formal analysis|Investigation	Formal analysis	Analyzed the data	Formal analysis	YES
6418696	30796049	AP	CRediT	Conceptualization|Validation|Formal analysis|Investigation	Investigation	Performed the experiments	Investigation	YES
6418696	30796049	DB	CRediT	Conceptualization|Writing|Visualization|Supervision|Project administration|Funding acquisition	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6418696	30796049	DB	CRediT	Conceptualization|Writing|Visualization|Supervision|Project administration|Funding acquisition	Writing	Wrote the paper	-	YES
6418696	30796049	DB	CRediT	Conceptualization|Writing|Visualization|Supervision|Project administration|Funding acquisition	Visualization	Analyzed the data	Visualization	YES
6418696	30796049	DB	CRediT	Conceptualization|Writing|Visualization|Supervision|Project administration|Funding acquisition	Supervision	-	Supervision	YES
6418696	30796049	DB	CRediT	Conceptualization|Writing|Visualization|Supervision|Project administration|Funding acquisition	Project administration	-	Project administration	YES
6418696	30796049	DB	CRediT	Conceptualization|Writing|Visualization|Supervision|Project administration|Funding acquisition	Funding acquisition	-	Funding acquisition	YES
6418696	30796049	FB	CRediT	Validation|Formal analysis|Investigation	Validation	Performed the experiments	Validation	YES
6418696	30796049	FB	CRediT	Validation|Formal analysis|Investigation	Formal analysis	Analyzed the data	Formal analysis	YES
6418696	30796049	FB	CRediT	Validation|Formal analysis|Investigation	Investigation	Performed the experiments	Investigation	YES
6418696	30796049	JS	CRediT	Validation|Investigation	Validation	Performed the experiments	Validation	YES
6418696	30796049	JS	CRediT	Validation|Investigation	Investigation	Performed the experiments	Investigation	YES
6418696	30796049	LW	CRediT	Formal analysis|Investigation	Formal analysis	Analyzed the data	Formal analysis	YES
6418696	30796049	LW	CRediT	Formal analysis|Investigation	Investigation	Performed the experiments	Investigation	YES
6418696	30796049	PN	CRediT	Funding acquisition	Funding acquisition	-	Funding acquisition	YES
5811644	29479363	AP	PLoS52	conceived and designed the experiment|collected all data|analyzed the data|interpreted the data|wrote the paper with|performed a critical revision and approved this final version of the manuscript to be published	conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5811644	29479363	AP	PLoS52	conceived and designed the experiment|collected all data|analyzed the data|interpreted the data|wrote the paper with|performed a critical revision and approved this final version of the manuscript to be published	collected all data	Performed the experiments	Investigation	YES
5811644	29479363	AP	PLoS52	conceived and designed the experiment|collected all data|analyzed the data|interpreted the data|wrote the paper with|performed a critical revision and approved this final version of the manuscript to be published	analyzed the data	Analyzed the data	Formal analysis	YES
5811644	29479363	AP	PLoS52	conceived and designed the experiment|collected all data|analyzed the data|interpreted the data|wrote the paper with|performed a critical revision and approved this final version of the manuscript to be published	interpreted the data	Analyzed the data	Formal analysis	YES
5811644	29479363	AP	PLoS52	conceived and designed the experiment|collected all data|analyzed the data|interpreted the data|wrote the paper with|performed a critical revision and approved this final version of the manuscript to be published	wrote the paper with	Wrote the paper	Writing - Original Draft	YES
5811644	29479363	AP	PLoS52	conceived and designed the experiment|collected all data|analyzed the data|interpreted the data|wrote the paper with|performed a critical revision and approved this final version of the manuscript to be published	performed a critical revision and approved this final version of the manuscript to be published	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5811644	29479363	BG	PLoS52	conceived and designed the experiment|analyzed the data|performed a critical revision and approved this final version of the manuscript to be published	conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5811644	29479363	BG	PLoS52	conceived and designed the experiment|analyzed the data|performed a critical revision and approved this final version of the manuscript to be published	analyzed the data	Analyzed the data	Formal analysis	YES
5811644	29479363	BG	PLoS52	conceived and designed the experiment|analyzed the data|performed a critical revision and approved this final version of the manuscript to be published	performed a critical revision and approved this final version of the manuscript to be published	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5811644	29479363	CvL	PLoS52	analyzed the data|interpreted the data|assisted with the wrote the paper with|performed a critical revision and approved this final version of the manuscript to be published	analyzed the data	Analyzed the data	Formal analysis	YES
5811644	29479363	CvL	PLoS52	analyzed the data|interpreted the data|assisted with the wrote the paper with|performed a critical revision and approved this final version of the manuscript to be published	interpreted the data	Analyzed the data	Formal analysis	YES
5811644	29479363	CvL	PLoS52	analyzed the data|interpreted the data|assisted with the wrote the paper with|performed a critical revision and approved this final version of the manuscript to be published	assisted with the wrote the paper with	Wrote the paper	Writing - Original Draft	YES
5811644	29479363	CvL	PLoS52	analyzed the data|interpreted the data|assisted with the wrote the paper with|performed a critical revision and approved this final version of the manuscript to be published	performed a critical revision and approved this final version of the manuscript to be published	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5811644	29479363	EB	PLoS52	conceived and designed the experiment|interpreted the data|assisted with the wrote the paper with|performed a critical revision and approved this final version of the manuscript to be published	conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5811644	29479363	EB	PLoS52	conceived and designed the experiment|interpreted the data|assisted with the wrote the paper with|performed a critical revision and approved this final version of the manuscript to be published	interpreted the data	Analyzed the data	Formal analysis	YES
5811644	29479363	EB	PLoS52	conceived and designed the experiment|interpreted the data|assisted with the wrote the paper with|performed a critical revision and approved this final version of the manuscript to be published	assisted with the wrote the paper with	Wrote the paper	Writing - Original Draft	YES
5811644	29479363	EB	PLoS52	conceived and designed the experiment|interpreted the data|assisted with the wrote the paper with|performed a critical revision and approved this final version of the manuscript to be published	performed a critical revision and approved this final version of the manuscript to be published	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5811644	29479363	JM	PLoS52	collected all data|interpreted the data|performed a critical revision and approved this final version of the manuscript to be published	collected all data	Performed the experiments	Investigation	YES
5811644	29479363	JM	PLoS52	collected all data|interpreted the data|performed a critical revision and approved this final version of the manuscript to be published	interpreted the data	Analyzed the data	Formal analysis	YES
5811644	29479363	JM	PLoS52	collected all data|interpreted the data|performed a critical revision and approved this final version of the manuscript to be published	performed a critical revision and approved this final version of the manuscript to be published	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
6270755	25429557	Fengqiong Li	2	performed research	performed research	Performed the experiments	Investigation	YES
6270755	25429557	Jianyou Shi	2	designed research	designed research	Conceived and designed the experiments	Methodology	YES
6270755	25429557	Mei Zhang	2	designed research	designed research	Conceived and designed the experiments	Methodology	YES
6270755	25429557	Rong Hu	2	performed research	performed research	Performed the experiments	Investigation	YES
6270755	25429557	Rongsheng Tong	2	performed research	performed research	Performed the experiments	Investigation	YES
6270755	25429557	Yanyang He	2	performed research	performed research	Performed the experiments	Investigation	YES
5769350	29338696	AOS	2	was a major contributor in experimental design, feedback on data analysis, and in editing the manuscript	was a major contributor in experimental design, feedback on data analysis, and in editing the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Review & Editing	YES
5769350	29338696	SL	2	conceived and designed experiments, prepared biological samples, extracted ribosomal depleted rna for rna seq, performed all data analysis, and drafted manuscript	conceived and designed experiments, prepared biological samples, extracted ribosomal depleted rna for rna seq, performed all data analysis, and drafted manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
1976598	17895978	DH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1976598	17895978	DH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1976598	17895978	DH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1976598	17895978	HL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1976598	17895978	HL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1976598	17895978	HL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1976598	17895978	HM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1976598	17895978	HM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1976598	17895978	HM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1976598	17895978	HM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1976598	17895978	MM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1976598	17895978	MM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1976598	17895978	OG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1976598	17895978	OG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1976598	17895978	OG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416912	25933160	DC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416912	25933160	DC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416912	25933160	DC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416912	25933160	DM	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416912	25933160	DM	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416912	25933160	DS	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416912	25933160	DS	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416912	25933160	DS	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416912	25933160	DS	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416912	25933160	FA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416912	25933160	FA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4416912	25933160	FA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4416912	25933160	FA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416912	25933160	IWR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416912	25933160	IWR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416912	25933160	IWR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416912	25933160	IWR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416912	25933160	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416912	25933160	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416912	25933160	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416912	25933160	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416912	25933160	LD	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416912	25933160	LD	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416912	25933160	LD	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416912	25933160	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416912	25933160	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4416912	25933160	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416912	25933160	MP	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416912	25933160	MP	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416912	25933160	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416912	25933160	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4416912	25933160	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416912	25933160	SPG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416912	25933160	SPG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416912	25933160	SPG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416912	25933160	TH	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416912	25933160	WH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416912	25933160	WH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416912	25933160	WH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3284243	22297447	CMN	2	sample collection	sample collection	Performed the experiments	Investigation	YES
3284243	22297447	CS	2	immunohistochemistry and data analysis	immunohistochemistry and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3284243	22297447	FC	2	consultant for anatomical pathology	consultant for anatomical pathology	Performed the experiments	Investigation	YES
3284243	22297447	GZ	2	data analysis and manuscript writing	data analysis and manuscript writing	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3284243	22297447	PI	2	manuscript writing	manuscript writing	Wrote the paper	Writing - Original Draft	YES
3284243	22297447	RP	2	confocal analysis	confocal analysis	-	-	NO
3284243	22297447	VB	2	sample collection	sample collection	Performed the experiments	Investigation	YES
3284243	22297447	VDF	2	manuscript writing	manuscript writing	Wrote the paper	Writing - Original Draft	YES
5758488	29313157	AZ	2	participated in the setup operation and maintenance of the bioreactors	participated in the setup operation and maintenance of the bioreactors	Performed the experiments	Investigation	YES
5758488	29313157	All	2	datasets supporting the conclusions of the manuscript were included in the article	datasets supporting the conclusions of the manuscript were included in the article	-	-	NO
5758488	29313157	All authors	2	read and approved the final manuscript|gave their consent for publication	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5758488	29313157	All authors	2	read and approved the final manuscript|gave their consent for publication	gave their consent for publication	-	-	NO
5758488	29313157	JJ	2	participated in the data analysis for the pyrosequencing results and revised the manuscript	participated in the data analysis for the pyrosequencing results and revised the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
5758488	29313157	Jiaguang Zhang	2	participated in the setup operation and maintenance of the bioreactors	participated in the setup operation and maintenance of the bioreactors	Performed the experiments	Investigation	YES
5758488	29313157	Jie Zhang	2	conceived the idea of the study, put forward the hypothesis and made the final revisions of figures, and gave the final approval for publication	conceived the idea of the study, put forward the hypothesis and made the final revisions of figures, and gave the final approval for publication	Conceived and designed the experiments|Wrote the paper	Conceptualization|Visualization|Writing - Review & Editing	YES
5758488	29313157	RS	2	designed and carried out the experiments, performed the data analysis, and drafted the manuscript	designed and carried out the experiments, performed the data analysis, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5758488	29313157	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5758488	29313157	XY	2	conceived the idea of the study, put forward the hypothesis and made the final revisions of figures, and gave the final approval for publication	conceived the idea of the study, put forward the hypothesis and made the final revisions of figures, and gave the final approval for publication	Conceived and designed the experiments|Wrote the paper	Conceptualization|Visualization|Writing - Review & Editing	YES
5758488	29313157	YL	2	participated in the data analysis for the pyrosequencing results and revised the manuscript	participated in the data analysis for the pyrosequencing results and revised the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
5758488	29313157	YZ	2	designed and carried out the experiments, performed the data analysis, and drafted the manuscript	designed and carried out the experiments, performed the data analysis, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5003862	27574314	E.T.B.	2	designed the experimental study	designed the experimental study	Conceived and designed the experiments	Methodology	YES
5003862	27574314	F.V.	2	analysed data	analysed data	Analyzed the data	Formal analysis	YES
5003862	27574314	I.M.G.	2	designed the experimental study	designed the experimental study	Conceived and designed the experiments	Methodology	YES
5003862	27574314	K.J.W.	2	analysed data	analysed data	Analyzed the data	Formal analysis	YES
5003862	27574314	K.W.	2	analysed data	analysed data	Analyzed the data	Formal analysis	YES
5003862	27574314	M.G.K.	2	analysed data	analysed data	Analyzed the data	Formal analysis	YES
5003862	27574314	P.B.J.	2	designed the experimental study	designed the experimental study	Conceived and designed the experiments	Methodology	YES
5003862	27574314	P.E.V.	2	analysed data	analysed data	Analyzed the data	Formal analysis	YES
5003862	27574314	P.F.	2	designed the experimental study	designed the experimental study	Conceived and designed the experiments	Methodology	YES
5003862	27574314	R.J.D.	2	designed the experimental study	designed the experimental study	Conceived and designed the experiments	Methodology	YES
5003862	27574314	R.R.-G.	2	analysed data	analysed data	Analyzed the data	Formal analysis	YES
5003862	27574314	T.R.	2	analysed data	analysed data	Analyzed the data	Formal analysis	YES
5003862	27574314	all authors	2	contributed to writing the paper	contributed to writing the paper	Wrote the paper	Writing - Original Draft	YES
6270756	25090115	A.F-T	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6270756	25090115	A.F-T	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
6270756	25090115	A.F-T	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
6270756	25090115	A.F-T	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270756	25090115	C.A.	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
6270756	25090115	C.A.	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270756	25090115	I.M.	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6270756	25090115	I.M.	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
6270756	25090115	I.M.	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270756	25090115	I.S.	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6270756	25090115	I.S.	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
6270756	25090115	J.F-L	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6270756	25090115	J.F-L	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
6270756	25090115	M.A.	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
6270756	25090115	M.A.	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270756	25090115	M.T.	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6270756	25090115	M.T.	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
6270756	25090115	M.T.	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6443201	30814124	AA	2	for data analysis	for data analysis	Analyzed the data	Formal analysis	YES
6443201	30814124	AB	2	for es cell work|for analysis of adults	for es cell work	Performed the experiments	Investigation	YES
6443201	30814124	AB	2	for es cell work|for analysis of adults	for analysis of adults	-	-	NO
6443201	30814124	CB-C	2	for in situs	for in situs	-	-	NO
6443201	30814124	GC-T	2	for analysis of adults	for analysis of adults	-	-	NO
6443201	30814124	IC	2	for analysis of adults	for analysis of adults	-	-	NO
6443201	30814124	IR	2	for genome editing	for genome editing	Wrote the paper	Writing - Review & Editing	YES
6443201	30814124	JSA	2	wrote the manuscript with input from all authors	wrote the manuscript with input from all authors	Wrote the paper	Writing - Original Draft	YES
6443201	30814124	MM	2	wrote the manuscript with input from all authors	wrote the manuscript with input from all authors	Wrote the paper	Writing - Original Draft	YES
6443201	30814124	MT	2	for es cell work	for es cell work	Performed the experiments	Investigation	YES
6443201	30814124	SM	2	for embryo work and tissue culture	for embryo work and tissue culture	Performed the experiments	Investigation	YES
6443201	30814124	WJ	2	for data analysis	for data analysis	Analyzed the data	Formal analysis	YES
4416914	25933115	AB	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416914	25933115	AB	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416914	25933115	BB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416914	25933115	BB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416914	25933115	BB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416914	25933115	BW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416914	25933115	BW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416914	25933115	BW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416914	25933115	BW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416914	25933115	CV	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416914	25933115	CV	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5811934	29479357	AV	2	conducted the majority of the experimental work with technical help and|contributed toward designing of experiments, interpretation of results, and writing of the manuscript	conducted the majority of the experimental work with technical help and	Performed the experiments	Investigation	YES
5811934	29479357	AV	2	conducted the majority of the experimental work with technical help and|contributed toward designing of experiments, interpretation of results, and writing of the manuscript	contributed toward designing of experiments, interpretation of results, and writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5811934	29479357	DB	2	contributed with the conducted the majority of the experimental work with technical help and	contributed with the conducted the majority of the experimental work with technical help and	Performed the experiments	Investigation	YES
5811934	29479357	JK	2	conducted the majority of the experimental work with technical help and|contributed toward designing of experiments, interpretation of results, and writing of the manuscript	conducted the majority of the experimental work with technical help and	Performed the experiments	Investigation	YES
5811934	29479357	JK	2	conducted the majority of the experimental work with technical help and|contributed toward designing of experiments, interpretation of results, and writing of the manuscript	contributed toward designing of experiments, interpretation of results, and writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5811934	29479357	LH	2	contributed with the conducted the majority of the experimental work with technical help and	contributed with the conducted the majority of the experimental work with technical help and	Performed the experiments	Investigation	YES
5811934	29479357	RP	2	contributed with the conducted the majority of the experimental work with technical help and	contributed with the conducted the majority of the experimental work with technical help and	Performed the experiments	Investigation	YES
5811934	29479357	SP	2	contributed toward designing of experiments, interpretation of results, and writing of the manuscript	contributed toward designing of experiments, interpretation of results, and writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5811934	29479357	SRC	2	conducted the majority of the experimental work with technical help and|contributed toward designing of experiments, interpretation of results, and writing of the manuscript	conducted the majority of the experimental work with technical help and	Performed the experiments	Investigation	YES
5811934	29479357	SRC	2	conducted the majority of the experimental work with technical help and|contributed toward designing of experiments, interpretation of results, and writing of the manuscript	contributed toward designing of experiments, interpretation of results, and writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5811934	29479357	ZR	2	contributed with the conducted the majority of the experimental work with technical help and	contributed with the conducted the majority of the experimental work with technical help and	Performed the experiments	Investigation	YES
4637081	26583129	All authors	2	contributed equally to this work	contributed equally to this work	-	-	NO
5769442	29334897	BM	2	performed experiments and analysed data	performed experiments and analysed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5769442	29334897	DKG	2	performed experiments and analysed data|wrote the manuscript, with contributions from the other authors	performed experiments and analysed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5769442	29334897	DKG	2	performed experiments and analysed data|wrote the manuscript, with contributions from the other authors	wrote the manuscript, with contributions from the other authors	Wrote the paper	Writing - Original Draft	YES
5769442	29334897	FH	2	conceived the study|performed experiments and analysed data|wrote the manuscript, with contributions from the other authors	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5769442	29334897	FH	2	conceived the study|performed experiments and analysed data|wrote the manuscript, with contributions from the other authors	performed experiments and analysed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5769442	29334897	FH	2	conceived the study|performed experiments and analysed data|wrote the manuscript, with contributions from the other authors	wrote the manuscript, with contributions from the other authors	Wrote the paper	Writing - Original Draft	YES
5769442	29334897	HK	2	conceived the study|performed experiments and analysed data|wrote the manuscript, with contributions from the other authors	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5769442	29334897	HK	2	conceived the study|performed experiments and analysed data|wrote the manuscript, with contributions from the other authors	performed experiments and analysed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5769442	29334897	HK	2	conceived the study|performed experiments and analysed data|wrote the manuscript, with contributions from the other authors	wrote the manuscript, with contributions from the other authors	Wrote the paper	Writing - Original Draft	YES
5769442	29334897	MJP	2	performed experiments and analysed data	performed experiments and analysed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5769442	29334897	MR	2	conceived the study|performed experiments and analysed data|wrote the manuscript, with contributions from the other authors	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5769442	29334897	MR	2	conceived the study|performed experiments and analysed data|wrote the manuscript, with contributions from the other authors	performed experiments and analysed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5769442	29334897	MR	2	conceived the study|performed experiments and analysed data|wrote the manuscript, with contributions from the other authors	wrote the manuscript, with contributions from the other authors	Wrote the paper	Writing - Original Draft	YES
5769442	29334897	MT	2	conceived the study|wrote the manuscript, with contributions from the other authors	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5769442	29334897	MT	2	conceived the study|wrote the manuscript, with contributions from the other authors	wrote the manuscript, with contributions from the other authors	Wrote the paper	Writing - Original Draft	YES
5769442	29334897	RH	2	performed experiments and analysed data	performed experiments and analysed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5769442	29334897	RS	2	performed experiments and analysed data	performed experiments and analysed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5769442	29334897	VK	2	performed experiments and analysed data	performed experiments and analysed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
1978073	17589564	AW	PLoS5	Analyzed the data|Confirmed statistical analysis	Analyzed the data	Analyzed the data	Formal analysis	YES
1978073	17589564	AW	PLoS5	Analyzed the data|Confirmed statistical analysis	Confirmed statistical analysis	Analyzed the data	Formal analysis	YES
1978073	17589564	JL	PLoS5	Analyzed the data|Confirmed statistical analysis	Analyzed the data	Analyzed the data	Formal analysis	YES
1978073	17589564	JL	PLoS5	Analyzed the data|Confirmed statistical analysis	Confirmed statistical analysis	Analyzed the data	Formal analysis	YES
1978073	17589564	JT	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1978073	17589564	JT	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1978073	17589564	LB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1978073	17589564	LB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1978073	17589564	LB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1978073	17589564	MT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1978073	17589564	MT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1978073	17589564	MT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1978073	17589564	MT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1978073	17589564	TT	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1978073	17589564	TT	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
6270757	24918543	Aizhen Huang	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
6270757	24918543	Fan Yang	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
6270757	24918543	Fangli Ma	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
6270757	24918543	Haifeng Li	PLoS52	conceived and designed the research|performed the experiments|analyzed the data|wrote and revised the manuscript	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
6270757	24918543	Haifeng Li	PLoS52	conceived and designed the research|performed the experiments|analyzed the data|wrote and revised the manuscript	performed the experiments	Performed the experiments	Investigation	YES
6270757	24918543	Haifeng Li	PLoS52	conceived and designed the research|performed the experiments|analyzed the data|wrote and revised the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
6270757	24918543	Haifeng Li	PLoS52	conceived and designed the research|performed the experiments|analyzed the data|wrote and revised the manuscript	wrote and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6270757	24918543	Jingjing Deng	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
6270757	24918543	Ju Zhang	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
6270757	24918543	Lingyun Xiao	PLoS52	conceived and designed the research|performed the experiments|analyzed the data|wrote and revised the manuscript	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
6270757	24918543	Lingyun Xiao	PLoS52	conceived and designed the research|performed the experiments|analyzed the data|wrote and revised the manuscript	performed the experiments	Performed the experiments	Investigation	YES
6270757	24918543	Lingyun Xiao	PLoS52	conceived and designed the research|performed the experiments|analyzed the data|wrote and revised the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
6270757	24918543	Lingyun Xiao	PLoS52	conceived and designed the research|performed the experiments|analyzed the data|wrote and revised the manuscript	wrote and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6270757	24918543	Ming Liang	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
6270757	24918543	Minghua Hu	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
6270757	24918543	Zebo Huang	PLoS52	conceived and designed the research|wrote and revised the manuscript	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
6270757	24918543	Zebo Huang	PLoS52	conceived and designed the research|wrote and revised the manuscript	wrote and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5812032	29479364	CR	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5812032	29479364	MI	PLoS52	designed and planned the experiments|performed the experiments|analyzed the data|drafted the manuscript	designed and planned the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5812032	29479364	MI	PLoS52	designed and planned the experiments|performed the experiments|analyzed the data|drafted the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5812032	29479364	MI	PLoS52	designed and planned the experiments|performed the experiments|analyzed the data|drafted the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5812032	29479364	MI	PLoS52	designed and planned the experiments|performed the experiments|analyzed the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5812032	29479364	PD	PLoS52	designed and planned the experiments|analyzed the data	designed and planned the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5812032	29479364	PD	PLoS52	designed and planned the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5769444	29334895	All authors	2	contributed to the design|contributed to the interpretation of findings	contributed to the design	Conceived and designed the experiments	-	YES
5769444	29334895	All authors	2	contributed to the design|contributed to the interpretation of findings	contributed to the interpretation of findings	Analyzed the data	Formal analysis	YES
5769444	29334895	MA	2	performed the bioinformatic analysis	performed the bioinformatic analysis	Performed the experiments	Formal analysis|Investigation	YES
5769444	29334895	MI	2	acquired the exome data	acquired the exome data	Performed the experiments	Investigation	YES
5769444	29334895	MK	2	conceived the idea|performed the bioinformatic analysis	conceived the idea	Conceived and designed the experiments	Conceptualization	YES
5769444	29334895	MK	2	conceived the idea|performed the bioinformatic analysis	performed the bioinformatic analysis	Performed the experiments	Formal analysis|Investigation	YES
5769444	29334895	MOEA	2	acquired the exome data|performed the bioinformatic analysis	acquired the exome data	Performed the experiments	Investigation	YES
5769444	29334895	MOEA	2	acquired the exome data|performed the bioinformatic analysis	performed the bioinformatic analysis	Performed the experiments	Formal analysis|Investigation	YES
5003864	27574316	J.D.	2	conceived of the project|edited the paper	conceived of the project	Conceived and designed the experiments	Conceptualization	YES
5003864	27574316	J.D.	2	conceived of the project|edited the paper	edited the paper	Wrote the paper	Writing - Review & Editing	YES
5003864	27574316	N.K.	2	conceived of the project|performed the analyses and wrote the paper	conceived of the project	Conceived and designed the experiments	Conceptualization	YES
5003864	27574316	N.K.	2	conceived of the project|performed the analyses and wrote the paper	performed the analyses and wrote the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5003864	27574316	RDM	2	sampling distribution	sampling distribution	Performed the experiments	Investigation	YES
4416915	25933064	AA	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416915	25933064	AG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416915	25933064	AK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416915	25933064	AMK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416915	25933064	AMK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416915	25933064	AMK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416915	25933064	AMK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416915	25933064	AMK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416915	25933064	BP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416915	25933064	BP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416915	25933064	BP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416915	25933064	BP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416915	25933064	BP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416915	25933064	JR	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4416915	25933064	JR	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416915	25933064	JS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416915	25933064	MO	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416915	25933064	MPO	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416915	25933064	MPO	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416915	25933064	MPO	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416915	25933064	MU	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416915	25933064	MU	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416915	25933064	MU	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416915	25933064	MU	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416915	25933064	PD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416915	25933064	PD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416915	25933064	PD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416915	25933064	PD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416915	25933064	TO	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5758489	29313259	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5758489	29313259	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5758489	29313259	Youth Outstanding Teachers	2	of henan province	of henan province	-	-	NO
1978457	17895970	DN	PLoS5	Wrote the paper|Conceived study	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1978457	17895970	DN	PLoS5	Wrote the paper|Conceived study	Conceived study	Conceived and designed the experiments	Conceptualization	YES
1978457	17895970	HC	PLoS5	Wrote the paper|Conceived models|Assembled database	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1978457	17895970	HC	PLoS5	Wrote the paper|Conceived models|Assembled database	Conceived models	Conceived and designed the experiments|Performed the experiments	Conceptualization|Methodology	YES
1978457	17895970	HC	PLoS5	Wrote the paper|Conceived models|Assembled database	Assembled database	Contributed reagents/materials/analysis tools	Software	YES
1978457	17895970	J-FG	PLoS5	Conceived models|Assembled database	Conceived models	Conceived and designed the experiments|Performed the experiments	Conceptualization|Methodology	YES
1978457	17895970	J-FG	PLoS5	Conceived models|Assembled database	Assembled database	Contributed reagents/materials/analysis tools	Software	YES
1978457	17895970	JG	PLoS5	Analyzed models|Conceived models	Analyzed models	Performed the experiments|Analyzed the data	Formal analysis|Methodology	YES
1978457	17895970	JG	PLoS5	Analyzed models|Conceived models	Conceived models	Conceived and designed the experiments|Performed the experiments	Conceptualization|Methodology	YES
1978457	17895970	MC	PLoS5	Conceived models|Assembled database	Conceived models	Conceived and designed the experiments|Performed the experiments	Conceptualization|Methodology	YES
1978457	17895970	MC	PLoS5	Conceived models|Assembled database	Assembled database	Contributed reagents/materials/analysis tools	Software	YES
1978457	17895970	MH	PLoS5	Wrote the paper|Conceived study|Obtained funding for study	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1978457	17895970	MH	PLoS5	Wrote the paper|Conceived study|Obtained funding for study	Conceived study	Conceived and designed the experiments	Conceptualization	YES
1978457	17895970	MH	PLoS5	Wrote the paper|Conceived study|Obtained funding for study	Obtained funding for study	-	Funding acquisition	YES
6443203	30804004	APG	2	contributed to the experimental design, acquisition and analysis of the work|drafted and revised the manuscript	contributed to the experimental design, acquisition and analysis of the work	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6443203	30804004	APG	2	contributed to the experimental design, acquisition and analysis of the work|drafted and revised the manuscript	drafted and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6443203	30804004	FF	2	contributed to the conception of the work|contributed to the experimental design, acquisition and analysis of the work	contributed to the conception of the work	Conceived and designed the experiments	Conceptualization	YES
6443203	30804004	FF	2	contributed to the conception of the work|contributed to the experimental design, acquisition and analysis of the work	contributed to the experimental design, acquisition and analysis of the work	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6443203	30804004	LYC	2	contributed to the conception of the work|contributed to the experimental design, acquisition and analysis of the work|drafted and revised the manuscript	contributed to the conception of the work	Conceived and designed the experiments	Conceptualization	YES
6443203	30804004	LYC	2	contributed to the conception of the work|contributed to the experimental design, acquisition and analysis of the work|drafted and revised the manuscript	contributed to the experimental design, acquisition and analysis of the work	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6443203	30804004	LYC	2	contributed to the conception of the work|contributed to the experimental design, acquisition and analysis of the work|drafted and revised the manuscript	drafted and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6443203	30804004	MS	2	contributed to the conception of the work|contributed to the experimental design, acquisition and analysis of the work	contributed to the conception of the work	Conceived and designed the experiments	Conceptualization	YES
6443203	30804004	MS	2	contributed to the conception of the work|contributed to the experimental design, acquisition and analysis of the work	contributed to the experimental design, acquisition and analysis of the work	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6443203	30804004	OC	2	contributed to the experimental design, acquisition and analysis of the work	contributed to the experimental design, acquisition and analysis of the work	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6443203	30804004	PP	2	contributed to the experimental design, acquisition and analysis of the work	contributed to the experimental design, acquisition and analysis of the work	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6443203	30804004	TF	2	contributed to the experimental design, acquisition and analysis of the work	contributed to the experimental design, acquisition and analysis of the work	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6270758	24566320	Chih-Jen Chang	2	were responsible for designing and conducting the study, interpreting the data, and writing the manuscript	were responsible for designing and conducting the study, interpreting the data, and writing the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
6270758	24566320	Feng-Hwa Lu	2	contributed to data collection, analysis, and interpretation	contributed to data collection, analysis, and interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270758	24566320	Hao-Chang Hung	2	contributed to data collection, analysis, and interpretation	contributed to data collection, analysis, and interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270758	24566320	Horng-Yih Ou	2	contributed to data collection, analysis, and interpretation	contributed to data collection, analysis, and interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270758	24566320	Hung-Tsung Wu	2	were responsible for designing and conducting the study, interpreting the data, and writing the manuscript	were responsible for designing and conducting the study, interpreting the data, and writing the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
6270758	24566320	Jin-Shang Wu	2	contributed to data interpretation	contributed to data interpretation	Analyzed the data	Formal analysis	YES
6270758	24566320	Yi-Ching Yang	2	contributed to data interpretation	contributed to data interpretation	Analyzed the data	Formal analysis	YES
6270758	24566320	Yu-Chu Su	2	contributed to data collection, analysis, and interpretation	contributed to data collection, analysis, and interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4416916	25932919	CS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416916	25932919	CS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416916	25932919	CS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416916	25932919	CS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416916	25932919	CS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416916	25932919	DO	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416916	25932919	DO	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416916	25932919	JB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416916	25932919	JB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416916	25932919	JB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416916	25932919	JB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416916	25932919	LG	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416916	25932919	LG	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416916	25932919	LG	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416916	25932919	MG	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416916	25932919	MG	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416916	25932919	PM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416916	25932919	PM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416916	25932919	PM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416916	25932919	SS	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416916	25932919	SS	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416916	25932919	YH	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416916	25932919	YH	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5769455	29338682	DY	2	participated in the design of the study	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
5769455	29338682	FH	2	provided the gmagl1 gene	provided the gmagl1 gene	-	-	NO
5769455	29338682	HD	2	carried out the molecular genetic studies	carried out the molecular genetic studies	Performed the experiments	Investigation	YES
5769455	29338682	HL	2	carried out the molecular genetic studies|participated in drafted the manuscript, took the photos of the plant materials and drew the figures	carried out the molecular genetic studies	Performed the experiments	Investigation	YES
5769455	29338682	HL	2	carried out the molecular genetic studies|participated in drafted the manuscript, took the photos of the plant materials and drew the figures	participated in drafted the manuscript, took the photos of the plant materials and drew the figures	Performed the experiments|Wrote the paper	Investigation|Visualization|Writing - Original Draft	YES
5769455	29338682	JW	2	participated in the sequence alignment and performed the computational analysis	participated in the sequence alignment and performed the computational analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5769455	29338682	Sujing Wang	2	participated in the phenotypic data collection and performed the statistical analysis	participated in the phenotypic data collection and performed the statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5769455	29338682	WY	2	carried out the molecular genetic studies	carried out the molecular genetic studies	Performed the experiments	Investigation	YES
5769455	29338682	XZ	2	participated in the design of the study|carried out the molecular genetic studies|participated in the phenotypic data collection and performed the statistical analysis|participated in the sequence alignment and performed the computational analysis|participated in drafted the manuscript, took the photos of the plant materials and drew the figures	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
5769455	29338682	XZ	2	participated in the design of the study|carried out the molecular genetic studies|participated in the phenotypic data collection and performed the statistical analysis|participated in the sequence alignment and performed the computational analysis|participated in drafted the manuscript, took the photos of the plant materials and drew the figures	carried out the molecular genetic studies	Performed the experiments	Investigation	YES
5769455	29338682	XZ	2	participated in the design of the study|carried out the molecular genetic studies|participated in the phenotypic data collection and performed the statistical analysis|participated in the sequence alignment and performed the computational analysis|participated in drafted the manuscript, took the photos of the plant materials and drew the figures	participated in the phenotypic data collection and performed the statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5769455	29338682	XZ	2	participated in the design of the study|carried out the molecular genetic studies|participated in the phenotypic data collection and performed the statistical analysis|participated in the sequence alignment and performed the computational analysis|participated in drafted the manuscript, took the photos of the plant materials and drew the figures	participated in the sequence alignment and performed the computational analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5769455	29338682	XZ	2	participated in the design of the study|carried out the molecular genetic studies|participated in the phenotypic data collection and performed the statistical analysis|participated in the sequence alignment and performed the computational analysis|participated in drafted the manuscript, took the photos of the plant materials and drew the figures	participated in drafted the manuscript, took the photos of the plant materials and drew the figures	Performed the experiments|Wrote the paper	Investigation|Visualization|Writing - Original Draft	YES
5769455	29338682	YC	2	provided the gmagl1 gene	provided the gmagl1 gene	-	-	NO
1978512	17895981	GA	PLoS5	Analyzed the data|Wrote the paper|Wrote the first draft of the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1978512	17895981	GA	PLoS5	Analyzed the data|Wrote the paper|Wrote the first draft of the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1978512	17895981	GA	PLoS5	Analyzed the data|Wrote the paper|Wrote the first draft of the paper	Wrote the first draft of the paper	Wrote the paper	Writing - Original Draft	YES
1978512	17895981	KO	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1978512	17895981	KO	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5812252	29479366	All authors	PLoS52	wrote and revised the paper, and approved the final version	wrote and revised the paper, and approved the final version	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5812252	29479366	CR	PLoS52	collected the data|interpreted the results	collected the data	Performed the experiments	Investigation	YES
5812252	29479366	CR	PLoS52	collected the data|interpreted the results	interpreted the results	Analyzed the data	Formal analysis	YES
5812252	29479366	CdP	PLoS52	interpreted the results	interpreted the results	Analyzed the data	Formal analysis	YES
5812252	29479366	D-ZL	PLoS52	conceived the study|interpreted the results	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5812252	29479366	D-ZL	PLoS52	conceived the study|interpreted the results	interpreted the results	Analyzed the data	Formal analysis	YES
5812252	29479366	HW	PLoS52	conceived the study|collected the data	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5812252	29479366	HW	PLoS52	conceived the study|collected the data	collected the data	Performed the experiments	Investigation	YES
5812252	29479366	LL	PLoS52	collected the data|interpreted the results	collected the data	Performed the experiments	Investigation	YES
5812252	29479366	LL	PLoS52	collected the data|interpreted the results	interpreted the results	Analyzed the data	Formal analysis	YES
5812252	29479366	RC	PLoS52	collected the data	collected the data	Performed the experiments	Investigation	YES
5812252	29479366	W-BY	PLoS52	conceived the study|collected the data|analyzed the data|interpreted the results	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5812252	29479366	W-BY	PLoS52	conceived the study|collected the data|analyzed the data|interpreted the results	collected the data	Performed the experiments	Investigation	YES
5812252	29479366	W-BY	PLoS52	conceived the study|collected the data|analyzed the data|interpreted the results	analyzed the data	Analyzed the data	Formal analysis	YES
5812252	29479366	W-BY	PLoS52	conceived the study|collected the data|analyzed the data|interpreted the results	interpreted the results	Analyzed the data	Formal analysis	YES
6443208	30850388	AH	2	performed pulldown and yeast experiments|analysed data	performed pulldown and yeast experiments	Performed the experiments	Investigation	YES
6443208	30850388	AH	2	performed pulldown and yeast experiments|analysed data	analysed data	Analyzed the data	Formal analysis	YES
6443208	30850388	CR	2	designed research|performed pulldown and yeast experiments|analysed data	designed research	Conceived and designed the experiments	Methodology	YES
6443208	30850388	CR	2	designed research|performed pulldown and yeast experiments|analysed data	performed pulldown and yeast experiments	Performed the experiments	Investigation	YES
6443208	30850388	CR	2	designed research|performed pulldown and yeast experiments|analysed data	analysed data	Analyzed the data	Formal analysis	YES
6443208	30850388	JK-V	2	designed research|analysed data|wrote and all co-authors commented on the manuscript	designed research	Conceived and designed the experiments	Methodology	YES
6443208	30850388	JK-V	2	designed research|analysed data|wrote and all co-authors commented on the manuscript	analysed data	Analyzed the data	Formal analysis	YES
6443208	30850388	JK-V	2	designed research|analysed data|wrote and all co-authors commented on the manuscript	wrote and all co-authors commented on the manuscript	Wrote the paper	Writing - Original Draft	YES
6443208	30850388	KD	2	designed research|conducted most experiments|analysed data|wrote and all co-authors commented on the manuscript	designed research	Conceived and designed the experiments	Methodology	YES
6443208	30850388	KD	2	designed research|conducted most experiments|analysed data|wrote and all co-authors commented on the manuscript	conducted most experiments	Performed the experiments	Investigation	YES
6443208	30850388	KD	2	designed research|conducted most experiments|analysed data|wrote and all co-authors commented on the manuscript	analysed data	Analyzed the data	Formal analysis	YES
6443208	30850388	KD	2	designed research|conducted most experiments|analysed data|wrote and all co-authors commented on the manuscript	wrote and all co-authors commented on the manuscript	Wrote the paper	Writing - Original Draft	YES
6443208	30850388	MIF	2	established multiple mutants|analysed data	established multiple mutants	Performed the experiments	Investigation	YES
6443208	30850388	MIF	2	established multiple mutants|analysed data	analysed data	Analyzed the data	Formal analysis	YES
6443208	30850388	SG	2	performed pulldown and yeast experiments|analysed data	performed pulldown and yeast experiments	Performed the experiments	Investigation	YES
6443208	30850388	SG	2	performed pulldown and yeast experiments|analysed data	analysed data	Analyzed the data	Formal analysis	YES
4424707	25960876	HI	2	participated in data interpretation, and drafted the manuscript	participated in data interpretation, and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4424707	25960876	MI	2	participated in data interpretation, and drafted the manuscript	participated in data interpretation, and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4424707	25960876	MN	2	conceived the study|participated in the design of the study|participated in data interpretation, and drafted the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4424707	25960876	MN	2	conceived the study|participated in the design of the study|participated in data interpretation, and drafted the manuscript	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
4424707	25960876	MN	2	conceived the study|participated in the design of the study|participated in data interpretation, and drafted the manuscript	participated in data interpretation, and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4424707	25960876	NO	2	participated in data interpretation, and drafted the manuscript	participated in data interpretation, and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4424707	25960876	YC	2	conceived the study|participated in the design of the study|participated in data interpretation, and drafted the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4424707	25960876	YC	2	conceived the study|participated in the design of the study|participated in data interpretation, and drafted the manuscript	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
4424707	25960876	YC	2	conceived the study|participated in the design of the study|participated in data interpretation, and drafted the manuscript	participated in data interpretation, and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5764898	29327267	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5764898	29327267	DW	PLoS52	wrote the paper|designed the research	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5764898	29327267	DW	PLoS52	wrote the paper|designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
5764898	29327267	GRY	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5764898	29327267	HBJ	PLoS52	wrote the paper|designed the research	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5764898	29327267	HBJ	PLoS52	wrote the paper|designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
5764898	29327267	HFL	PLoS52	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5764898	29327267	JJW	PLoS52	wrote the paper|designed the research|obtained funding	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5764898	29327267	JJW	PLoS52	wrote the paper|designed the research|obtained funding	designed the research	Conceived and designed the experiments	Methodology	YES
5764898	29327267	JJW	PLoS52	wrote the paper|designed the research|obtained funding	obtained funding	-	Funding acquisition	YES
5764898	29327267	SHL	PLoS52	carried out the experiments|wrote the paper|designed the research	carried out the experiments	Performed the experiments	Investigation	YES
5764898	29327267	SHL	PLoS52	carried out the experiments|wrote the paper|designed the research	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5764898	29327267	SHL	PLoS52	carried out the experiments|wrote the paper|designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
5764898	29327267	WD	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5764898	29327267	YY	PLoS52	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
3352132	22472891	ACC	2	study conception and design|experiments, data acquisition and analysis|drafting the manuscript	study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
3352132	22472891	ACC	2	study conception and design|experiments, data acquisition and analysis|drafting the manuscript	experiments, data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3352132	22472891	ACC	2	study conception and design|experiments, data acquisition and analysis|drafting the manuscript	drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
3352132	22472891	AIS	2	study conception and design|drafting the manuscript	study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
3352132	22472891	AIS	2	study conception and design|drafting the manuscript	drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
3352132	22472891	AT	2	critical discussion and text revision	critical discussion and text revision	Wrote the paper	Writing - Review & Editing	YES
3352132	22472891	FA	2	experiments, data acquisition and analysis	experiments, data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3352132	22472891	GB	2	study conception and design|drafting the manuscript	study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
3352132	22472891	GB	2	study conception and design|drafting the manuscript	drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
3352132	22472891	GS	2	experiments, data acquisition and analysis	experiments, data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3352132	22472891	VG	2	study conception and design|experiments, data acquisition and analysis	study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
3352132	22472891	VG	2	study conception and design|experiments, data acquisition and analysis	experiments, data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5031613	27619692	All authors	2	contributed equally to the structure and writing of this review and approved of the final submission	contributed equally to the structure and writing of this review and approved of the final submission	Wrote the paper	Writing - Review & Editing	YES
5031613	27619692	E.L.M.	2	conducted bioinformatic analyses of pneumococcal phage	conducted bioinformatic analyses of pneumococcal phage	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3886619	24453810	Laura Lorenzon	2	contributed equally to the study	contributed equally to the study	-	-	NO
3886619	24453810	Paolo Mercantini	2	contributed equally to the study	contributed equally to the study	-	-	NO
1978513	17895982	BP	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1978513	17895982	EC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1978513	17895982	MY	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270759	25211004	A.Y.	2	contributed to the preparation of the manuscript	contributed to the preparation of the manuscript	Wrote the paper	Writing - Original Draft	YES
6270759	25211004	B.N.I.	2	contributed to the preparation of the manuscript	contributed to the preparation of the manuscript	Wrote the paper	Writing - Original Draft	YES
6270759	25211004	Beatrice Irungu	2	has collected and extracted the roots and the leaves, and has fractionated and isolated their constituents	has collected and extracted the roots and the leaves, and has fractionated and isolated their constituents	Performed the experiments	Investigation	YES
6270759	25211004	M.E.	2	contributed to the preparation of the manuscript	contributed to the preparation of the manuscript	Wrote the paper	Writing - Original Draft	YES
4416917	25933371	BES	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416917	25933371	BES	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416917	25933371	BES	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416917	25933371	HH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416917	25933371	HH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416917	25933371	HH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416917	25933371	HH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416917	25933371	HH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416917	25933371	HJ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416917	25933371	HJ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416917	25933371	HJ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416917	25933371	HP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416917	25933371	HP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416917	25933371	HP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416917	25933371	JT	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416917	25933371	JT	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416917	25933371	JT	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416917	25933371	THR	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416917	25933371	THR	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416917	25933371	THR	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5769502	29334892	HC	PLoS52	assembled the sequences and analyzed the data|performed the experiments|wrote the manuscript	assembled the sequences and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5769502	29334892	HC	PLoS52	assembled the sequences and analyzed the data|performed the experiments|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5769502	29334892	HC	PLoS52	assembled the sequences and analyzed the data|performed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5769502	29334892	SY	PLoS52	analyzed the data and modified the manuscript critically	analyzed the data and modified the manuscript critically	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5769502	29334892	WZ	PLoS52	assembled the sequences and analyzed the data|wrote the manuscript	assembled the sequences and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5769502	29334892	WZ	PLoS52	assembled the sequences and analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5769502	29334892	XL	PLoS52	performed the sampling and sequence analysis	performed the sampling and sequence analysis	Performed the experiments	Investigation	YES
5769502	29334892	YP	PLoS52	analyzed the data and modified the manuscript critically	analyzed the data and modified the manuscript critically	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5769502	29334892	YW	PLoS52	conceived and designed this study|wrote the manuscript|analyzed the data	conceived and designed this study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5769502	29334892	YW	PLoS52	conceived and designed this study|wrote the manuscript|analyzed the data	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5769502	29334892	YW	PLoS52	conceived and designed this study|wrote the manuscript|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
4637087	26583145	Emil Sundstrup	2	collected the data	collected the data	Performed the experiments	Investigation	YES
4637087	26583145	Kenneth Jay	2	educated the training instructors	educated the training instructors	-	Supervision	YES
4637087	26583145	Lars L. Andersen	2	designed the study|performed the statistical analyses	designed the study	Conceived and designed the experiments	Methodology	YES
4637087	26583145	Lars L. Andersen	2	designed the study|performed the statistical analyses	performed the statistical analyses	Analyzed the data	Formal analysis	YES
4637087	26583145	Markus D. Jakobsen	2	developed the mechanical muscle tests for this study|designed the study|collected the data	developed the mechanical muscle tests for this study	-	-	NO
4637087	26583145	Markus D. Jakobsen	2	developed the mechanical muscle tests for this study|designed the study|collected the data	designed the study	Conceived and designed the experiments	Methodology	YES
4637087	26583145	Markus D. Jakobsen	2	developed the mechanical muscle tests for this study|designed the study|collected the data	collected the data	Performed the experiments	Investigation	YES
4637087	26583145	Mikkel Brandt	2	collected the data	collected the data	Performed the experiments	Investigation	YES
6443209	30796050	CCR	2	performed the fission yeast genetic screen	performed the fission yeast genetic screen	Performed the experiments	Investigation	YES
6443209	30796050	ESMC	2	performed the majority of the experiments	performed the majority of the experiments	Performed the experiments	Investigation	YES
6443209	30796050	IAA	2	performed the mass spectrometry analysis	performed the mass spectrometry analysis	Performed the experiments	Investigation	YES
6443209	30796050	IML	2	performed the mass spectrometry analysis	performed the mass spectrometry analysis	Performed the experiments	Investigation	YES
6443209	30796050	JME	2	conceived the study and designed the experiments|performed the majority of the experiments|wrote the manuscript	conceived the study and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6443209	30796050	JME	2	conceived the study and designed the experiments|performed the majority of the experiments|wrote the manuscript	performed the majority of the experiments	Performed the experiments	Investigation	YES
6443209	30796050	JME	2	conceived the study and designed the experiments|performed the majority of the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6443209	30796050	MG	2	performed the fission yeast genetic screen	performed the fission yeast genetic screen	Performed the experiments	Investigation	YES
6443209	30796050	MG-F	2	conceived the study and designed the experiments	conceived the study and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6443209	30796050	MGF	2	wrote the manuscript|supervised the research	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6443209	30796050	MGF	2	wrote the manuscript|supervised the research	supervised the research	-	Supervision	YES
6443209	30796050	SC	2	performed the 2d gel experiments	performed the 2d gel experiments	Performed the experiments	Investigation	YES
6443209	30796050	SM	2	performed the 2d gel experiments	performed the 2d gel experiments	Performed the experiments	Investigation	YES
5812337	29479358	AR	2	designed experiments	designed experiments	Conceived and designed the experiments	Methodology	YES
5812337	29479358	AU	2	performed wet-lab experiments	performed wet-lab experiments	Performed the experiments	Investigation	YES
5812337	29479358	FW	2	designed experiments	designed experiments	Conceived and designed the experiments	Methodology	YES
5812337	29479358	HL	2	performed wet-lab experiments	performed wet-lab experiments	Performed the experiments	Investigation	YES
5812337	29479358	HW	2	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5812337	29479358	JF	2	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5812337	29479358	JR	2	designed experiments|performed wet-lab experiments	designed experiments	Conceived and designed the experiments	Methodology	YES
5812337	29479358	JR	2	designed experiments|performed wet-lab experiments	performed wet-lab experiments	Performed the experiments	Investigation	YES
5812337	29479358	SH	2	maintained and provided rp1 lines	maintained and provided rp1 lines	-	-	NO
5812337	29479358	SL	2	designed experiments|analyzed data	designed experiments	Conceived and designed the experiments	Methodology	YES
5812337	29479358	SL	2	designed experiments|analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5812337	29479358	TD	2	performed wet-lab experiments	performed wet-lab experiments	Performed the experiments	Investigation	YES
5812337	29479358	The authors	2	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	Performed the experiments	Investigation	YES
5812337	29479358	W. All	2	authors read and approved the final manuscript	authors read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5812337	29479358	YH	2	designed experiments|analyzed data|performed wet-lab experiments	designed experiments	Conceived and designed the experiments	Methodology	YES
5812337	29479358	YH	2	designed experiments|analyzed data|performed wet-lab experiments	analyzed data	Analyzed the data	Formal analysis	YES
5812337	29479358	YH	2	designed experiments|analyzed data|performed wet-lab experiments	performed wet-lab experiments	Performed the experiments	Investigation	YES
5812337	29479358	ZP	2	performed wet-lab experiments	performed wet-lab experiments	Performed the experiments	Investigation	YES
1978514	17896003	BK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1978514	17896003	BK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1978514	17896003	BK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1978514	17896003	CS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1978514	17896003	CS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1978514	17896003	RN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1978514	17896003	RN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1978514	17896003	RN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1978514	17896003	RN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3352133	22472892	AIS	2	design of experiments and manuscript writing	design of experiments and manuscript writing	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3352133	22472892	CA	2	execution of experiments	execution of experiments	Performed the experiments	Investigation	YES
3352133	22472892	CS	2	execution of experiments	execution of experiments	Performed the experiments	Investigation	YES
3352133	22472892	GS	2	execution of experiments	execution of experiments	Performed the experiments	Investigation	YES
3352133	22472892	MGB	2	design of experiments and manuscript writing	design of experiments and manuscript writing	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3352133	22472892	PV	2	execution of experiments	execution of experiments	Performed the experiments	Investigation	YES
5783978	29368130	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5783978	29368130	DKO	PLoS52	designed the experiments, interpreted the results, and wrote the manuscript	designed the experiments, interpreted the results, and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5783978	29368130	EJY	PLoS52	designed the experiments, interpreted the results, and wrote the manuscript|performed the experiments	designed the experiments, interpreted the results, and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5783978	29368130	EJY	PLoS52	designed the experiments, interpreted the results, and wrote the manuscript|performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5783978	29368130	KCS	PLoS52	designed the experiments, interpreted the results, and wrote the manuscript|performed the experiments	designed the experiments, interpreted the results, and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5783978	29368130	KCS	PLoS52	designed the experiments, interpreted the results, and wrote the manuscript|performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5783978	29368130	THK	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5783978	29368130	The authors	PLoS52	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
4424709	25960878	KN	2	carried out the fecal examination and performed the statistical analysis of fecal examination	carried out the fecal examination and performed the statistical analysis of fecal examination	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4424709	25960878	NS	2	conceived the study, participated in its design and coordination, and helped draft the manuscript	conceived the study, participated in its design and coordination, and helped draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
4424709	25960878	TA	2	carried out the fecal examination and performed the statistical analysis of fecal examination	carried out the fecal examination and performed the statistical analysis of fecal examination	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4424709	25960878	TI	2	participated in the design of the study and revised it critically for important intellectual content	participated in the design of the study and revised it critically for important intellectual content	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
4424709	25960878	TU	2	carried out the clinical data acquisition, performed the statistical analysis of clinical data, and drafted the manuscript	carried out the clinical data acquisition, performed the statistical analysis of clinical data, and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6270760	25036152	Abdelrahman O. Ezzat	2	finalized the experimental work	finalized the experimental work	Performed the experiments	Investigation	YES
4416918	25933418	DK	PLoS5	Conceived and designed the experiments|Contributed to the editing of the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416918	25933418	DK	PLoS5	Conceived and designed the experiments|Contributed to the editing of the manuscript	Contributed to the editing of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4416918	25933418	HSY	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416918	25933418	HSY	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416918	25933418	HSY	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416918	25933418	HWL	PLoS5	Wrote the paper|Contributed to the editing of the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416918	25933418	HWL	PLoS5	Wrote the paper|Contributed to the editing of the manuscript	Contributed to the editing of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4416918	25933418	JJY	PLoS5	Analyzed the data|Wrote the paper|Contributed to the editing of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4416918	25933418	JJY	PLoS5	Analyzed the data|Wrote the paper|Contributed to the editing of the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416918	25933418	JJY	PLoS5	Analyzed the data|Wrote the paper|Contributed to the editing of the manuscript	Contributed to the editing of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4416918	25933418	JKL	PLoS5	Conceived and designed the experiments|Contributed to the editing of the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416918	25933418	JKL	PLoS5	Conceived and designed the experiments|Contributed to the editing of the manuscript	Contributed to the editing of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4416918	25933418	JYC	PLoS5	Contributed to interpretation of the results	Contributed to interpretation of the results	Analyzed the data	Formal analysis	YES
4416918	25933418	MS	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416918	25933418	MS	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416918	25933418	SAL	PLoS5	Contributed to interpretation of the results	Contributed to interpretation of the results	Analyzed the data	Formal analysis	YES
4416918	25933418	SH	PLoS5	Contributed to interpretation of the results	Contributed to interpretation of the results	Analyzed the data	Formal analysis	YES
1978515	17895992	WF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1978515	17895992	WF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1978515	17895992	WF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1978515	17895992	WF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1978515	17895992	WF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3352134	22472893	HSL	2	histological specimen preparation and immunostaining	histological specimen preparation and immunostaining	Performed the experiments	Investigation	YES
3352134	22472893	JHC	2	histological specimen preparation and immunostaining	histological specimen preparation and immunostaining	Performed the experiments	Investigation	YES
3352134	22472893	SKK	2	histological reading and manuscript preparing	histological reading and manuscript preparing	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5031618	27619697	All authors	2	contributed to the design and the writing of this review	contributed to the design and the writing of this review	Conceived and designed the experiments|Wrote the paper	Writing - Review & Editing	YES
5812350	29479365	D-ZL	2	designed this research	designed this research	Conceived and designed the experiments	Methodology	YES
5812350	29479365	HW	2	designed this research	designed this research	Conceived and designed the experiments	Methodology	YES
5812350	29479365	J-JJ	2	assembled the plastomes	assembled the plastomes	-	-	NO
5812350	29479365	S-DZ	2	collected some species and extracted dna	collected some species and extracted dna	Performed the experiments	Investigation	YES
5812350	29479365	S-YC	2	assembled the plastomes	assembled the plastomes	-	-	NO
5812350	29479365	SW	2	wrote the manuscript, and all authors revised it	wrote the manuscript, and all authors revised it	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5812350	29479365	T-SY	2	designed this research|wrote the manuscript, and all authors revised it	designed this research	Conceived and designed the experiments	Methodology	YES
5812350	29479365	T-SY	2	designed this research|wrote the manuscript, and all authors revised it	wrote the manuscript, and all authors revised it	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5812350	29479365	Y-HW	2	designed this research|conducted the experiments and analyses|wrote the manuscript, and all authors revised it	designed this research	Conceived and designed the experiments	Methodology	YES
5812350	29479365	Y-HW	2	designed this research|conducted the experiments and analyses|wrote the manuscript, and all authors revised it	conducted the experiments and analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5812350	29479365	Y-HW	2	designed this research|conducted the experiments and analyses|wrote the manuscript, and all authors revised it	wrote the manuscript, and all authors revised it	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5771032	29338691	All of the authors	2	contributed to manuscript preparation	contributed to manuscript preparation	Wrote the paper	Writing - Original Draft	YES
5771032	29338691	JF	2	contributed to the usability aspects	contributed to the usability aspects	-	-	NO
5771032	29338691	OT	2	supervised and coordinated the work and provided ideas for its development	supervised and coordinated the work and provided ideas for its development	Conceived and designed the experiments	Conceptualization|Project administration|Supervision	YES
5771032	29338691	SD	2	contributed to software development	contributed to software development	Contributed reagents/materials/analysis tools	Software	YES
5783979	29368022	All	2	data generated or analyzed during this study are included in this published article and the associated additional file	data generated or analyzed during this study are included in this published article and the associated additional file	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5783979	29368022	All authors	2	participated in discussion of the experiments, revised the manuscript and agreed to the final content|read and approved the final manuscript|give their consent for publication	participated in discussion of the experiments, revised the manuscript and agreed to the final content	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5783979	29368022	All authors	2	participated in discussion of the experiments, revised the manuscript and agreed to the final content|read and approved the final manuscript|give their consent for publication	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5783979	29368022	All authors	2	participated in discussion of the experiments, revised the manuscript and agreed to the final content|read and approved the final manuscript|give their consent for publication	give their consent for publication	-	-	NO
5783979	29368022	BS	2	designed the experiments|performed the experiments, analyzed the results and prepared the first draft of the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5783979	29368022	BS	2	designed the experiments|performed the experiments, analyzed the results and prepared the first draft of the manuscript	performed the experiments, analyzed the results and prepared the first draft of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5783979	29368022	CXZ	2	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5783979	29368022	DW	2	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5783979	29368022	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5052738	27672145	D.D.P.	2	performed the experiments and wrote the manuscript|designed the experiments	performed the experiments and wrote the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5052738	27672145	D.D.P.	2	performed the experiments and wrote the manuscript|designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5052738	27672145	J.P.A.	2	contributed insight and fruitful discussions	contributed insight and fruitful discussions	-	-	NO
5052738	27672145	O.A.	2	analysed the single-molecule electroporation experiments	analysed the single-molecule electroporation experiments	-	-	NO
5052738	27672145	R.M.B.	2	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
6270761	25415480	Ales Obreza	PLoS52	designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
6270761	25415480	Boris Brus	PLoS52	performed the research and analyzed the data	performed the research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270761	25415480	Irena Mlinaric-Rascan	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270761	25415480	Izidor Sosic	PLoS52	performed the research and analyzed the data	performed the research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270761	25415480	Martina Gobec	PLoS52	performed the research and analyzed the data|wrote the paper	performed the research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270761	25415480	Martina Gobec	PLoS52	performed the research and analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270761	25415480	Stanislav Gobec	PLoS52	designed the research|wrote the paper	designed the research	Conceived and designed the experiments	Methodology	YES
6270761	25415480	Stanislav Gobec	PLoS52	designed the research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416919	25933375	AH	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416919	25933375	AH	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416919	25933375	AH	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416919	25933375	AV	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416919	25933375	AV	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416919	25933375	AV	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416919	25933375	JCKdJ	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416919	25933375	JCKdJ	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416919	25933375	JCKdJ	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416919	25933375	JH	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416919	25933375	JH	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416919	25933375	JH	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416919	25933375	MCZ	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416919	25933375	MCZ	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416919	25933375	MCZ	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416919	25933375	NSC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416919	25933375	NSC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416919	25933375	NSC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416919	25933375	OHF	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416919	25933375	OHF	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416919	25933375	OHF	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4424730	25960880	CC	2	participated in the design of the study, the design and recruitment of patients for the patient cohort, and the design of the statistical analyses and heavily reviewed and revised the manuscript	participated in the design of the study, the design and recruitment of patients for the patient cohort, and the design of the statistical analyses and heavily reviewed and revised the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Review & Editing	YES
4424730	25960880	EM	2	participated in the design of the study and drafted the manuscript	participated in the design of the study and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4424730	25960880	HZ	2	performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
4424730	25960880	JC	2	participated in the design of the study and reviewed and revised the manuscript	participated in the design of the study and reviewed and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
4424730	25960880	JS	2	participated in the design of the study and reviewed and revised the manuscript	participated in the design of the study and reviewed and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
4424730	25960880	KK	2	participated in the design of the study and reviewed and revised the manuscript	participated in the design of the study and reviewed and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
4424730	25960880	KL	2	participated in the design of the study and reviewed and revised the manuscript	participated in the design of the study and reviewed and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
4424730	25960880	MM	2	participated in the design of the study and reviewed and revised the manuscript	participated in the design of the study and reviewed and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
1978516	17895993	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1978516	17895993	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1978516	17895993	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1978516	17895993	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1978516	17895993	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1978516	17895993	AS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1978516	17895993	AS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1978516	17895993	DB	PLoS5	Contributed reagents/materials/analysis tools|Provided funding, edited manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1978516	17895993	DB	PLoS5	Contributed reagents/materials/analysis tools|Provided funding, edited manuscript	Provided funding, edited manuscript	Wrote the paper	Funding acquisition|Writing - Review & Editing	YES
1978516	17895993	SW	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1978516	17895993	SW	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5816074	29483922	BL	7	acquired the data, revised the paper, and approved of the submitted and final versions	acquired the data, revised the paper, and approved of the submitted and final versions	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5816074	29483922	PW	7	conceived and designed the field experiment, performed the experiment, analyzed the data, contributed reagents, materials, analysis tools, wrote the paper, prepared figures, and approved of the submitted and final versions	conceived and designed the field experiment, performed the experiment, analyzed the data, contributed reagents, materials, analysis tools, wrote the paper, prepared figures, and approved of the submitted and final versions	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Resources|Visualization|Writing - Original Draft	YES
5816074	29483922	RG	7	acquired the data, revised the paper, and approved of the submitted and final versions	acquired the data, revised the paper, and approved of the submitted and final versions	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5816074	29483922	SX	7	acquired the data, revised the paper, and approved of the submitted and final versions	acquired the data, revised the paper, and approved of the submitted and final versions	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5816074	29483922	SY	7	acquired the data, revised the paper, and approved of the submitted and final versions	acquired the data, revised the paper, and approved of the submitted and final versions	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5816074	29483922	ScX	7	conceived and designed the laboratory seed germination experiment, performed the experiments, analyzed, and interpreted the data, contributed reagents, materials, analysis tools, wrote the paper, prepared figures and tables, reviewed drafts of the paper and approved of the submitted and final versions	conceived and designed the laboratory seed germination experiment, performed the experiments, analyzed, and interpreted the data, contributed reagents, materials, analysis tools, wrote the paper, prepared figures and tables, reviewed drafts of the paper and approved of the submitted and final versions	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Resources|Visualization|Writing - Original Draft|Writing - Review & Editing	YES
5816074	29483922	XL	7	acquired the data, revised the paper, and approved of the submitted and final versions	acquired the data, revised the paper, and approved of the submitted and final versions	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5816074	29483922	XS	7	acquired the data, revised the paper, and approved of the submitted and final versions	acquired the data, revised the paper, and approved of the submitted and final versions	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5816074	29483922	XZ	7	acquired the data, revised the paper, and approved of the submitted and final versions	acquired the data, revised the paper, and approved of the submitted and final versions	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5816074	29483922	YZ	7	conceived and designed all experiments, interpreted the data, revised and reviewed drafts of the paper, and approved of the submitted and final versions	conceived and designed all experiments, interpreted the data, revised and reviewed drafts of the paper, and approved of the submitted and final versions	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
6270762	25401400	Chenghui Sun	PLoS52	performed research and analyzed the data|wrote the paper	performed research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270762	25401400	Chenghui Sun	PLoS52	performed research and analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270762	25401400	Fanfan Shen	PLoS52	designed research|performed research and analyzed the data|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
6270762	25401400	Fanfan Shen	PLoS52	designed research|performed research and analyzed the data|wrote the paper	performed research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270762	25401400	Fanfan Shen	PLoS52	designed research|performed research and analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270762	25401400	Penghao Lv	PLoS52	performed research and analyzed the data	performed research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270762	25401400	Rubo Zhang	PLoS52	performed research and analyzed the data	performed research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270762	25401400	Siping Pang	PLoS52	designed research|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
6270762	25401400	Siping Pang	PLoS52	designed research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5052740	27672147	All authors	2	contributed to the drafting of the manuscript	contributed to the drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
6463211	30842096	All authors	2	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
6463211	30842096	JZ	2	conceived, designed, and supervised the work|performed most of the experiments and analyzed data|performed crispr/cas9-based gene knockout and analyzed data|prepared figures|wrote the manuscript	conceived, designed, and supervised the work	Conceived and designed the experiments	Conceptualization|Supervision	YES
6463211	30842096	JZ	2	conceived, designed, and supervised the work|performed most of the experiments and analyzed data|performed crispr/cas9-based gene knockout and analyzed data|prepared figures|wrote the manuscript	performed most of the experiments and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6463211	30842096	JZ	2	conceived, designed, and supervised the work|performed most of the experiments and analyzed data|performed crispr/cas9-based gene knockout and analyzed data|prepared figures|wrote the manuscript	performed crispr/cas9-based gene knockout and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6463211	30842096	JZ	2	conceived, designed, and supervised the work|performed most of the experiments and analyzed data|performed crispr/cas9-based gene knockout and analyzed data|prepared figures|wrote the manuscript	prepared figures	-	Visualization	YES
6463211	30842096	JZ	2	conceived, designed, and supervised the work|performed most of the experiments and analyzed data|performed crispr/cas9-based gene knockout and analyzed data|prepared figures|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6463211	30842096	MN	2	conceived, designed, and supervised the work|wrote the manuscript	conceived, designed, and supervised the work	Conceived and designed the experiments	Conceptualization|Supervision	YES
6463211	30842096	MN	2	conceived, designed, and supervised the work|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6463211	30842096	RY	2	performed most of the experiments and analyzed data|performed crispr/cas9-based gene knockout and analyzed data|prepared figures|wrote the manuscript	performed most of the experiments and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6463211	30842096	RY	2	performed most of the experiments and analyzed data|performed crispr/cas9-based gene knockout and analyzed data|prepared figures|wrote the manuscript	performed crispr/cas9-based gene knockout and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6463211	30842096	RY	2	performed most of the experiments and analyzed data|performed crispr/cas9-based gene knockout and analyzed data|prepared figures|wrote the manuscript	prepared figures	-	Visualization	YES
6463211	30842096	RY	2	performed most of the experiments and analyzed data|performed crispr/cas9-based gene knockout and analyzed data|prepared figures|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6463211	30842096	S-BJ	2	performed crispr/cas9-based gene knockout and analyzed data	performed crispr/cas9-based gene knockout and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6463211	30842096	UL	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5783981	29368243	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5783981	29368243	BW	2	helped with the statistical design and data analysis	helped with the statistical design and data analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis	YES
5783981	29368243	CD	2	assisted in conducting experimental trials	assisted in conducting experimental trials	Performed the experiments	Investigation	YES
5783981	29368243	EY	2	conducted research work and drafted manuscript	conducted research work and drafted manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5783981	29368243	JY	2	participated in editing of the manuscript	participated in editing of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5783981	29368243	LF	2	supervised all experimental trials, contributed to experimental design, data analysis and review of manuscript	supervised all experimental trials, contributed to experimental design, data analysis and review of manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Supervision|Writing - Review & Editing	YES
5783981	29368243	SF	2	helped with the statistical design and data analysis	helped with the statistical design and data analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis	YES
5783981	29368243	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5783981	29368243	YJ	2	co-supervised the ph	co-supervised the ph	-	Supervision	YES
5771137	29338683	AP	2	verified and validated the genome	verified and validated the genome	Performed the experiments	Validation	YES
5771137	29338683	AR	2	prepared and sequenced the library	prepared and sequenced the library	Performed the experiments	Investigation	YES
5771137	29338683	EC	2	verified and validated the genome	verified and validated the genome	Performed the experiments	Validation	YES
5771137	29338683	FB-H	2	designed this project|analyzed the databases, genomes, and in silico sequencing	designed this project	Conceived and designed the experiments	Methodology	YES
5771137	29338683	FB-H	2	designed this project|analyzed the databases, genomes, and in silico sequencing	analyzed the databases, genomes, and in silico sequencing	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Software	YES
5771137	29338683	LA-A	2	designed this project|analyzed the databases, genomes, and in silico sequencing|performed the bacterial cultures and dna extractions|verified and validated the genome	designed this project	Conceived and designed the experiments	Methodology	YES
5771137	29338683	LA-A	2	designed this project|analyzed the databases, genomes, and in silico sequencing|performed the bacterial cultures and dna extractions|verified and validated the genome	analyzed the databases, genomes, and in silico sequencing	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Software	YES
5771137	29338683	LA-A	2	designed this project|analyzed the databases, genomes, and in silico sequencing|performed the bacterial cultures and dna extractions|verified and validated the genome	performed the bacterial cultures and dna extractions	Performed the experiments	Investigation	YES
5771137	29338683	LA-A	2	designed this project|analyzed the databases, genomes, and in silico sequencing|performed the bacterial cultures and dna extractions|verified and validated the genome	verified and validated the genome	Performed the experiments	Validation	YES
4424764	25960881	AU	2	are responsible for the study design and execution, data analysis, and report writing	are responsible for the study design and execution, data analysis, and report writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology	YES
4424764	25960881	KU	2	is involved in the execution of the study, data analysis, and report writing	is involved in the execution of the study, data analysis, and report writing	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation	YES
4424764	25960881	MW	2	is responsible for the study design and data collection	is responsible for the study design and data collection	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4424764	25960881	NI	2	is involved in study design and execution and data analysis	is involved in study design and execution and data analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
4424764	25960881	TK	2	are also involved in the study design and execution and data analysis and provided advice during write up	are also involved in the study design and execution and data analysis and provided advice during write up	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology	YES
4424764	25960881	YF	2	are responsible for the study design and execution, data analysis, and report writing	are responsible for the study design and execution, data analysis, and report writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology	YES
4424764	25960881	YS	2	are responsible for the study design and execution, data analysis, and report writing|are also involved in the study design and execution and data analysis and provided advice during write up	are responsible for the study design and execution, data analysis, and report writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology	YES
4424764	25960881	YS	2	are responsible for the study design and execution, data analysis, and report writing|are also involved in the study design and execution and data analysis and provided advice during write up	are also involved in the study design and execution and data analysis and provided advice during write up	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology	YES
4416920	25933409	CB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416920	25933409	ECA	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416920	25933409	GRH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416920	25933409	GRH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416920	25933409	GRH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416920	25933409	HMJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416920	25933409	HMJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416920	25933409	HMJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416920	25933409	HMJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416920	25933409	KDO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416920	25933409	KDO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416920	25933409	KDO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416920	25933409	KDO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416920	25933409	KWP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416920	25933409	LCG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416920	25933409	LGR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416920	25933409	LGR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416920	25933409	LGR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416920	25933409	WNF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416920	25933409	WNF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416920	25933409	WNF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416920	25933409	WNF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1978517	17912343	AO	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1978517	17912343	AO	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1978517	17912343	BP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1978517	17912343	BP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1978517	17912343	BP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1978517	17912343	FS	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1978517	17912343	FS	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1978517	17912343	JA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1978517	17912343	JA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1978517	17912343	JA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1978517	17912343	JA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1978517	17912343	JH	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1978517	17912343	JH	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1978517	17912343	JY	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1978517	17912343	JY	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1978517	17912343	RA	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1978517	17912343	RA	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1978517	17912343	SD	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1978517	17912343	SD	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1978517	17912343	SM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1978517	17912343	SM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1978517	17912343	SM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1978517	17912343	TI	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1978517	17912343	TI	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1978517	17912343	TI	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1978517	17912343	TK	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1978517	17912343	TK	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1978517	17912343	YC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1978517	17912343	YC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1978517	17912343	YC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1978517	17912343	YM	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1978517	17912343	YM	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1978517	17912343	ZJ	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1978517	17912343	ZJ	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5816337	29483921	AB-H	PLoS52	supervised the seq datasets under the|carried out other computational analyses|wrote the paper	supervised the seq datasets under the	-	Supervision	YES
5816337	29483921	AB-H	PLoS52	supervised the seq datasets under the|carried out other computational analyses|wrote the paper	carried out other computational analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5816337	29483921	AB-H	PLoS52	supervised the seq datasets under the|carried out other computational analyses|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5816337	29483921	AR	PLoS52	supervised the seq datasets under the|wrote the paper	supervised the seq datasets under the	-	Supervision	YES
5816337	29483921	AR	PLoS52	supervised the seq datasets under the|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5816337	29483921	CS	PLoS52	performed the analysis of basic gene expression, isoform transcripts assembly, and maintenance of the poplar genome browser for the project	performed the analysis of basic gene expression, isoform transcripts assembly, and maintenance of the poplar genome browser for the project	Performed the experiments	Investigation	YES
5816337	29483921	MH	PLoS52	developed the idiffir and tapis software and analyzed the rna seq and iso-seq datasets under the|carried out other computational analyses|wrote the paper	developed the idiffir and tapis software and analyzed the rna seq and iso-seq datasets under the	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Software	YES
5816337	29483921	MH	PLoS52	developed the idiffir and tapis software and analyzed the rna seq and iso-seq datasets under the|carried out other computational analyses|wrote the paper	carried out other computational analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5816337	29483921	MH	PLoS52	developed the idiffir and tapis software and analyzed the rna seq and iso-seq datasets under the|carried out other computational analyses|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5816337	29483921	PD	PLoS52	carried out the greenhouse experimental setup	carried out the greenhouse experimental setup	Performed the experiments	Investigation	YES
5816337	29483921	PJ	PLoS52	conceived the study and the project discussed in this paper|wrote the paper	conceived the study and the project discussed in this paper	Conceived and designed the experiments	Conceptualization	YES
5816337	29483921	PJ	PLoS52	conceived the study and the project discussed in this paper|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5816337	29483921	SF	PLoS52	conceived the study and the project discussed in this paper|carried out the greenhouse experimental setup|carried out all the experimental validations|carried out other computational analyses|wrote the paper	conceived the study and the project discussed in this paper	Conceived and designed the experiments	Conceptualization	YES
5816337	29483921	SF	PLoS52	conceived the study and the project discussed in this paper|carried out the greenhouse experimental setup|carried out all the experimental validations|carried out other computational analyses|wrote the paper	carried out the greenhouse experimental setup	Performed the experiments	Investigation	YES
5816337	29483921	SF	PLoS52	conceived the study and the project discussed in this paper|carried out the greenhouse experimental setup|carried out all the experimental validations|carried out other computational analyses|wrote the paper	carried out all the experimental validations	Performed the experiments	Investigation|Validation	YES
5816337	29483921	SF	PLoS52	conceived the study and the project discussed in this paper|carried out the greenhouse experimental setup|carried out all the experimental validations|carried out other computational analyses|wrote the paper	carried out other computational analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5816337	29483921	SF	PLoS52	conceived the study and the project discussed in this paper|carried out the greenhouse experimental setup|carried out all the experimental validations|carried out other computational analyses|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5816337	29483921	SS	PLoS52	assisted in rna extraction and ddpcr experiments	assisted in rna extraction and ddpcr experiments	Performed the experiments	Investigation	YES
5052741	27672148	E.C.	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5052741	27672148	F.H.	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4424765	25960882	HM	2	participated in its design and coordination and helped to draft the manuscript	participated in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Project administration|Writing - Original Draft	YES
4424765	25960882	HN	2	helped in the analysis of the data	helped in the analysis of the data	Analyzed the data	Formal analysis	YES
4424765	25960882	JT	2	participated in the conduction of the study	participated in the conduction of the study	Performed the experiments	Investigation	YES
4424765	25960882	NGAL	2	and adamts13	and adamts13	-	-	NO
4424765	25960882	NK	2	designed the study protocol and conducted the study	designed the study protocol and conducted the study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4424765	25960882	NS	2	helped in the analysis of the data	helped in the analysis of the data	Analyzed the data	Formal analysis	YES
4424765	25960882	SK	2	participated in the analysis and interpretation of the data	participated in the analysis and interpretation of the data	Analyzed the data	Formal analysis	YES
4424765	25960882	TS	2	helped in the assay and analysis of the data	helped in the assay and analysis of the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4424765	25960882	YI	2	participated in the analysis of the data and drafted the manuscript	participated in the analysis of the data and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5783984	29368263	CG	1	Conducted experiments and performed data analysis	Conducted experiments and performed data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5783984	29368263	CR	1	Wrote the manuscript or contributed to the manuscript	Wrote the manuscript or contributed to the manuscript	Wrote the paper	Writing - Original Draft	YES
5783984	29368263	DL	1	Conducted experiments and performed data analysis	Conducted experiments and performed data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5783984	29368263	JH	1	Conducted experiments and performed data analysis|Wrote the manuscript or contributed to the manuscript	Conducted experiments and performed data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5783984	29368263	JH	1	Conducted experiments and performed data analysis|Wrote the manuscript or contributed to the manuscript	Wrote the manuscript or contributed to the manuscript	Wrote the paper	Writing - Original Draft	YES
5783984	29368263	JL	1	Conducted experiments and performed data analysis	Conducted experiments and performed data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5783984	29368263	QY	1	Conducted experiments and performed data analysis|Wrote the manuscript or contributed to the manuscript	Conducted experiments and performed data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5783984	29368263	QY	1	Conducted experiments and performed data analysis|Wrote the manuscript or contributed to the manuscript	Wrote the manuscript or contributed to the manuscript	Wrote the paper	Writing - Original Draft	YES
5783984	29368263	YL	1	Conducted experiments and performed data analysis	Conducted experiments and performed data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5783984	29368263	YY	1	Participated in research design|Conducted experiments and performed data analysis|Wrote the manuscript or contributed to the manuscript	Participated in research design	Conceived and designed the experiments	-	YES
5783984	29368263	YY	1	Participated in research design|Conducted experiments and performed data analysis|Wrote the manuscript or contributed to the manuscript	Conducted experiments and performed data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5783984	29368263	YY	1	Participated in research design|Conducted experiments and performed data analysis|Wrote the manuscript or contributed to the manuscript	Wrote the manuscript or contributed to the manuscript	Wrote the paper	Writing - Original Draft	YES
5783984	29368263	ZZ	1	Participated in research design|Wrote the manuscript or contributed to the manuscript	Participated in research design	Conceived and designed the experiments	-	YES
5783984	29368263	ZZ	1	Participated in research design|Wrote the manuscript or contributed to the manuscript	Wrote the manuscript or contributed to the manuscript	Wrote the paper	Writing - Original Draft	YES
1978518	17895994	KS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1978518	17895994	KS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1978518	17895994	KS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5771141	29338715	All authors	2	were involved in drafting or revising the content of the manuscript	were involved in drafting or revising the content of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5771141	29338715	BR	2	conceived the entire study|analyzed and interpreted the genetic data	conceived the entire study	Conceived and designed the experiments	Conceptualization	YES
5771141	29338715	BR	2	conceived the entire study|analyzed and interpreted the genetic data	analyzed and interpreted the genetic data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5771141	29338715	DEL	2	implemented the genomics bioinformatics	implemented the genomics bioinformatics	Performed the experiments	Formal analysis|Investigation	YES
5771141	29338715	DGA	2	contributed to the sample collection	contributed to the sample collection	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5771141	29338715	GPMD	2	contributed to the sample collection|analyzed and interpreted the genetic data	contributed to the sample collection	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5771141	29338715	GPMD	2	contributed to the sample collection|analyzed and interpreted the genetic data	analyzed and interpreted the genetic data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5771141	29338715	JAV	2	conceived the entire study|contributed to the sample collection|analyzed and interpreted the genetic data	conceived the entire study	Conceived and designed the experiments	Conceptualization	YES
5771141	29338715	JAV	2	conceived the entire study|contributed to the sample collection|analyzed and interpreted the genetic data	contributed to the sample collection	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5771141	29338715	JAV	2	conceived the entire study|contributed to the sample collection|analyzed and interpreted the genetic data	analyzed and interpreted the genetic data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5771141	29338715	MDM	2	conceived the acquisition of data, analysis and interpretation of spatial environmental data from remote sensing and gis databases	conceived the acquisition of data, analysis and interpretation of spatial environmental data from remote sensing and gis databases	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Software	YES
5771141	29338715	MM	2	contributed to the sample collection	contributed to the sample collection	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5771141	29338715	PGP	2	contributed to the sample collection	contributed to the sample collection	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5771141	29338715	WEJ	2	analyzed and interpreted the genetic data	analyzed and interpreted the genetic data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4416921	25933004	AP	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416921	25933004	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416921	25933004	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416921	25933004	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416921	25933004	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416921	25933004	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416921	25933004	PK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416921	25933004	PK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416921	25933004	PK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416921	25933004	PK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416921	25933004	PK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3888728	24453858	Song Liu	2	contributed equally to this work	contributed equally to this work	-	-	NO
3888728	24453858	Zhiwu Hong	2	contributed equally to this work	contributed equally to this work	-	-	NO
3491817	22927122	BBF	2	contributed extensive revisions	contributed extensive revisions	Wrote the paper	Writing - Review & Editing	YES
3491817	22927122	ED	2	commented on the text	commented on the text	-	-	NO
3491817	22927122	EZR	2	commented on the text	commented on the text	-	-	NO
3491817	22927122	HK	2	provided material for the figures|contributed extensive revisions	provided material for the figures	Contributed reagents/materials/analysis tools	Resources|Visualization	YES
3491817	22927122	HK	2	provided material for the figures|contributed extensive revisions	contributed extensive revisions	Wrote the paper	Writing - Review & Editing	YES
3491817	22927122	LJ	2	provided material for the figures|commented on the text	provided material for the figures	Contributed reagents/materials/analysis tools	Resources|Visualization	YES
3491817	22927122	LJ	2	provided material for the figures|commented on the text	commented on the text	-	-	NO
3491817	22927122	MV	2	wrote the text, coordinated contributors and assembled the final version	wrote the text, coordinated contributors and assembled the final version	Wrote the paper	Project administration|Writing - Original Draft	YES
3491817	22927122	PJS	2	contributed extensive revisions	contributed extensive revisions	Wrote the paper	Writing - Review & Editing	YES
3491817	22927122	RH	2	commented on the text	commented on the text	-	-	NO
3491817	22927122	TT	2	contributed extensive revisions	contributed extensive revisions	Wrote the paper	Writing - Review & Editing	YES
3491817	22927122	UD	2	commented on the text	commented on the text	-	-	NO
5816579	29487606	ALS	2	conceived the main concept of the manuscript|wrote the manuscript	conceived the main concept of the manuscript	Conceived and designed the experiments	Conceptualization	YES
5816579	29487606	ALS	2	conceived the main concept of the manuscript|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5816579	29487606	All authors	2	participated in a workshop to discuss and develop the themes of the perspective article|reviewed, revised, and approved the final manuscript	participated in a workshop to discuss and develop the themes of the perspective article	Wrote the paper	Writing - Original Draft	YES
5816579	29487606	All authors	2	participated in a workshop to discuss and develop the themes of the perspective article|reviewed, revised, and approved the final manuscript	reviewed, revised, and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5816579	29487606	CD	2	conceived the main concept of the manuscript	conceived the main concept of the manuscript	Conceived and designed the experiments	Conceptualization	YES
5816579	29487606	MAR	2	conceived the main concept of the manuscript	conceived the main concept of the manuscript	Conceived and designed the experiments	Conceptualization	YES
5816579	29487606	PHY	2	conceived the main concept of the manuscript	conceived the main concept of the manuscript	Conceived and designed the experiments	Conceptualization	YES
5816579	29487606	PIM	2	conceived the main concept of the manuscript	conceived the main concept of the manuscript	Conceived and designed the experiments	Conceptualization	YES
4416922	25932648	DJT	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416922	25932648	GG	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4416922	25932648	GG	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416922	25932648	IK	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416922	25932648	IK	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416922	25932648	JTT	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4416922	25932648	JTT	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416922	25932648	LH	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416922	25932648	LH	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416922	25932648	PV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416922	25932648	PV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416922	25932648	PV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416922	25932648	PV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416922	25932648	TB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416922	25932648	TB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416922	25932648	TB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270765	24714190	A.F.	2	participated in the discussions and helped to revise it	participated in the discussions and helped to revise it	Wrote the paper	Writing - Review & Editing	YES
6270765	24714190	C.T.	2	participated in the discussions and helped to revise it	participated in the discussions and helped to revise it	Wrote the paper	Writing - Review & Editing	YES
6270765	24714190	K.N.	2	participated in the discussions and helped to revise it	participated in the discussions and helped to revise it	Wrote the paper	Writing - Review & Editing	YES
6270765	24714190	S.S.L.	2	conceived the idea and designed the structure of review article	conceived the idea and designed the structure of review article	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5783985	29368055	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5783985	29368055	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5771206	29338766	GZ	2	designed the study and was in charge of the overall project	designed the study and was in charge of the overall project	Conceived and designed the experiments	Methodology	YES
5771206	29338766	HC	2	contributed to the design and performing of the study, and writing of the manuscript	contributed to the design and performing of the study, and writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5771206	29338766	JW	2	designed the study and was in charge of the overall project	designed the study and was in charge of the overall project	Conceived and designed the experiments	Methodology	YES
5771206	29338766	MZ	2	contributed to the interpretation of data and writing of the manuscript	contributed to the interpretation of data and writing of the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
5771206	29338766	RL	2	contributed to the interpretation of data and writing of the manuscript	contributed to the interpretation of data and writing of the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
1978519	17912344	AR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1978519	17912344	AR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1978519	17912344	AR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1978519	17912344	AR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1978519	17912344	LS	PLoS5	Performed the experiments|Langers supervision	Performed the experiments	Performed the experiments	Investigation	YES
1978519	17912344	LS	PLoS5	Performed the experiments|Langers supervision	Langers supervision	-	Supervision	YES
1978519	17912344	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1978519	17912344	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1978519	17912344	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1978519	17912344	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1978519	17912344	UG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Edited the paper|Langer	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1978519	17912344	UG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Edited the paper|Langer	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1978519	17912344	UG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Edited the paper|Langer	Edited the paper	Wrote the paper	Writing - Review & Editing	YES
1978519	17912344	UG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Edited the paper|Langer	Langer	-	-	NO
5816676	29487604	BW	PLoS52	conceived and designed the experiments|performed rils dna isolation and phenotype data collecting|analyzed the sequencing data|conducted the qtl identification and further fine-mapping|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5816676	29487604	BW	PLoS52	conceived and designed the experiments|performed rils dna isolation and phenotype data collecting|analyzed the sequencing data|conducted the qtl identification and further fine-mapping|wrote the paper	performed rils dna isolation and phenotype data collecting	Performed the experiments	Investigation	YES
5816676	29487604	BW	PLoS52	conceived and designed the experiments|performed rils dna isolation and phenotype data collecting|analyzed the sequencing data|conducted the qtl identification and further fine-mapping|wrote the paper	analyzed the sequencing data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5816676	29487604	BW	PLoS52	conceived and designed the experiments|performed rils dna isolation and phenotype data collecting|analyzed the sequencing data|conducted the qtl identification and further fine-mapping|wrote the paper	conducted the qtl identification and further fine-mapping	Performed the experiments	Investigation	YES
5816676	29487604	BW	PLoS52	conceived and designed the experiments|performed rils dna isolation and phenotype data collecting|analyzed the sequencing data|conducted the qtl identification and further fine-mapping|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5816676	29487604	CG	PLoS52	performed rils dna isolation and phenotype data collecting	performed rils dna isolation and phenotype data collecting	Performed the experiments	Investigation	YES
5816676	29487604	HZ	PLoS52	conceived and designed the experiments|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5816676	29487604	HZ	PLoS52	conceived and designed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5816676	29487604	JC	PLoS52	performed rils dna isolation and phenotype data collecting	performed rils dna isolation and phenotype data collecting	Performed the experiments	Investigation	YES
5816676	29487604	JG	PLoS52	performed rils dna isolation and phenotype data collecting	performed rils dna isolation and phenotype data collecting	Performed the experiments	Investigation	YES
5816676	29487604	JL	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5816676	29487604	JZ	PLoS52	performed rils dna isolation and phenotype data collecting	performed rils dna isolation and phenotype data collecting	Performed the experiments	Investigation	YES
5816676	29487604	LE	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5816676	29487604	WL	PLoS52	performed rils dna isolation and phenotype data collecting	performed rils dna isolation and phenotype data collecting	Performed the experiments	Investigation	YES
5816676	29487604	WS	PLoS52	conceived and designed the experiments|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5816676	29487604	WS	PLoS52	conceived and designed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5816676	29487604	XD	PLoS52	analyzed the sequencing data	analyzed the sequencing data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5816676	29487604	XZ	PLoS52	performed rils dna isolation and phenotype data collecting	performed rils dna isolation and phenotype data collecting	Performed the experiments	Investigation	YES
5816676	29487604	YZ	PLoS52	performed rils dna isolation and phenotype data collecting|conducted the qtl identification and further fine-mapping	performed rils dna isolation and phenotype data collecting	Performed the experiments	Investigation	YES
5816676	29487604	YZ	PLoS52	performed rils dna isolation and phenotype data collecting|conducted the qtl identification and further fine-mapping	conducted the qtl identification and further fine-mapping	Performed the experiments	Investigation	YES
5816676	29487604	ZL	PLoS52	performed rils dna isolation and phenotype data collecting	performed rils dna isolation and phenotype data collecting	Performed the experiments	Investigation	YES
5052743	27672150	J.P.S.	2	wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
5052743	27672150	M.B.	2	wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
4416924	25933436	AR	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416924	25933436	AZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416924	25933436	AZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416924	25933436	AZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416924	25933436	AZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416924	25933436	MA	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416924	25933436	MA	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416924	25933436	SA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416924	25933436	SA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416924	25933436	SA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416924	25933436	SA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5783986	29368054	AK	2	performed biochemical and chemical analyses	performed biochemical and chemical analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5783986	29368054	AP	2	performed the evaluation of final feather hydrolysates	performed the evaluation of final feather hydrolysates	Performed the experiments	Investigation	YES
5783986	29368054	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5783986	29368054	BZ	2	isolated and maintained bacterial strains, led microbiological procedures	isolated and maintained bacterial strains, led microbiological procedures	Performed the experiments	Investigation	YES
5783986	29368054	DC	2	performed the evaluation of final feather hydrolysates	performed the evaluation of final feather hydrolysates	Performed the experiments	Investigation	YES
5783986	29368054	MP	2	performed biochemical and chemical analyses	performed biochemical and chemical analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5783986	29368054	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5783986	29368054	WK	2	advised on the concept and methods	advised on the concept and methods	Conceived and designed the experiments|Performed the experiments	Conceptualization	YES
5783986	29368054	WL	2	designed the work, created and analyzed optimization experimental designs, performed molecular identification of isolates, performed electrophoretic analysis, wrote the manuscript	designed the work, created and analyzed optimization experimental designs, performed molecular identification of isolates, performed electrophoretic analysis, wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
1978520	17895984	JT	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1978520	17895984	KK	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1978520	17895984	KK	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1978520	17895984	LS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1978520	17895984	LS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1978520	17895984	SQ	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1978520	17895984	UB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1978520	17895984	UB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1978520	17895984	UB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1978520	17895984	WM	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1978520	17895984	WM	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5816802	29487605	AC	2	who is the project coordinator of this work	who is the project coordinator of this work	-	Project administration	YES
5816802	29487605	AL	2	processed and analyzed the data with	processed and analyzed the data with	Analyzed the data	Data curation|Formal analysis	YES
5816802	29487605	RB	2	designed the research, contributed and coordinated the assembly of the italian aquatic plant database|helped with the processed and analyzed the data with	designed the research, contributed and coordinated the assembly of the italian aquatic plant database	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Project administration|Resources|Software	YES
5816802	29487605	RB	2	designed the research, contributed and coordinated the assembly of the italian aquatic plant database|helped with the processed and analyzed the data with	helped with the processed and analyzed the data with	Analyzed the data	Data curation|Formal analysis	YES
5773036	29343235	MERGE	2	assembly and data interpretation, and manuscript writing	assembly and data interpretation, and manuscript writing	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4416925	25932633	APS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416925	25932633	APS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416925	25932633	APS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416925	25932633	APS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416925	25932633	JM	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416925	25932633	LF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416925	25932633	LF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416925	25932633	LF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416925	25932633	LF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416925	25932633	MMO	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416925	25932633	MMO	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416925	25932633	VA	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5052745	27672152	A.G.	2	conceived, designed and drafted the article and approved the final version to be published	conceived, designed and drafted the article and approved the final version to be published	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5052745	27672152	V.T.L.	2	conceived, designed and drafted the article and approved the final version to be published	conceived, designed and drafted the article and approved the final version to be published	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4416926	25932631	AB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416926	25932631	AB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416926	25932631	AB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416926	25932631	AC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416926	25932631	AC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416926	25932631	AC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416926	25932631	AC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416926	25932631	DL	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416926	25932631	DL	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416926	25932631	FS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416926	25932631	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416926	25932631	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416926	25932631	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416926	25932631	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416926	25932631	MGB	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4416926	25932631	MGB	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416926	25932631	SB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416926	25932631	SC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416926	25932631	WH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5052747	27672154	A.M.	PLoS52	contributed new reagents/analytic tools|analysed data|wrote the paper	contributed new reagents/analytic tools	Contributed reagents/materials/analysis tools	Resources	YES
5052747	27672154	A.M.	PLoS52	contributed new reagents/analytic tools|analysed data|wrote the paper	analysed data	Analyzed the data	Formal analysis	YES
5052747	27672154	A.M.	PLoS52	contributed new reagents/analytic tools|analysed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5052747	27672154	J.R.P.	PLoS52	designed research|analysed data|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
5052747	27672154	J.R.P.	PLoS52	designed research|analysed data|wrote the paper	analysed data	Analyzed the data	Formal analysis	YES
5052747	27672154	J.R.P.	PLoS52	designed research|analysed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5052747	27672154	K.A.M.	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
5052747	27672154	N.C.	PLoS52	designed research|performed research|analysed data	designed research	Conceived and designed the experiments	Methodology	YES
5052747	27672154	N.C.	PLoS52	designed research|performed research|analysed data	performed research	Performed the experiments	Investigation	YES
5052747	27672154	N.C.	PLoS52	designed research|performed research|analysed data	analysed data	Analyzed the data	Formal analysis	YES
5052747	27672154	T.D.	PLoS52	contributed new reagents/analytic tools|analysed data|wrote the paper	contributed new reagents/analytic tools	Contributed reagents/materials/analysis tools	Resources	YES
5052747	27672154	T.D.	PLoS52	contributed new reagents/analytic tools|analysed data|wrote the paper	analysed data	Analyzed the data	Formal analysis	YES
5052747	27672154	T.D.	PLoS52	contributed new reagents/analytic tools|analysed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
1978521	17895973	CL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1978521	17895973	CL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1978521	17895973	CL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1978521	17895973	ML	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1978521	17895973	ML	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1978521	17895973	ML	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1978521	17895973	MP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1978521	17895973	MP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1978521	17895973	MP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1978521	17895973	RF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1978521	17895973	RF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1978521	17895973	RF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1978521	17895973	RF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3491821	22887873	All authors	2	revised and approved the manuscript	revised and approved the manuscript	Wrote the paper	Writing - Review & Editing	YES
3491821	22887873	IT	2	conceived and designed studies, synthesized compounds, performed biological studies and wrote the paper|designed and constructed quantification plasmids and performed rt pcr studies	conceived and designed studies, synthesized compounds, performed biological studies and wrote the paper	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Writing - Original Draft	YES
3491821	22887873	IT	2	conceived and designed studies, synthesized compounds, performed biological studies and wrote the paper|designed and constructed quantification plasmids and performed rt pcr studies	designed and constructed quantification plasmids and performed rt pcr studies	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3491821	22887873	KAJ	2	synthesized and analyzed dendrimers	synthesized and analyzed dendrimers	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3491821	22887873	MZ	2	performed modelling studies	performed modelling studies	Performed the experiments	Investigation|Methodology	YES
3491821	22887873	PMR	2	synthesized and analyzed dendrimers	synthesized and analyzed dendrimers	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3491821	22887873	SMT	2	synthesized and analyzed dendrimers	synthesized and analyzed dendrimers	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3491821	22887873	SS	2	conceived and designed studies, synthesized compounds, performed biological studies and wrote the paper	conceived and designed studies, synthesized compounds, performed biological studies and wrote the paper	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Writing - Original Draft	YES
3491821	22887873	TB	2	synthesized and analyzed dendrimers	synthesized and analyzed dendrimers	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3491821	22887873	TSB	2	performed modelling studies	performed modelling studies	Performed the experiments	Investigation|Methodology	YES
6270768	24983862	All the authors	2	made contributions in the preparation of the manuscript	made contributions in the preparation of the manuscript	Wrote the paper	Writing - Original Draft	YES
6270768	24983862	Charles A. Laughton	2	was a major contributor to the asp code development	was a major contributor to the asp code development	Contributed reagents/materials/analysis tools	Software	YES
6270768	24983862	Michael P. Mazanetz	2	performed the experiments described in the manuscript	performed the experiments described in the manuscript	Performed the experiments	Investigation	YES
6270768	24983862	Peter M. Fischer	2	devised the scientific rationale and coordinating the project work and sourced the research funding	devised the scientific rationale and coordinating the project work and sourced the research funding	Conceived and designed the experiments	Conceptualization|Funding acquisition|Project administration	YES
5783987	29368072	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5783987	29368072	GS	2	have done all the measurements and experiments and drafted the manuscript	have done all the measurements and experiments and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5783987	29368072	HZ	2	analyzed the data and contributed to the statistical analysis	analyzed the data and contributed to the statistical analysis	Analyzed the data	Formal analysis	YES
5783987	29368072	JM	2	analyzed the data and contributed to the statistical analysis	analyzed the data and contributed to the statistical analysis	Analyzed the data	Formal analysis	YES
5783987	29368072	MY	2	supervised and provided an important intellectual content in the research design, coordination of the study and contributed in the drafting of the manuscript	supervised and provided an important intellectual content in the research design, coordination of the study and contributed in the drafting of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Supervision|Writing - Original Draft	YES
5783987	29368072	YZ	2	supervised and provided an important intellectual content in the research design, coordination of the study and contributed in the drafting of the manuscript	supervised and provided an important intellectual content in the research design, coordination of the study and contributed in the drafting of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Supervision|Writing - Original Draft	YES
5783987	29368072	ZT	2	analyzed the data and contributed to the statistical analysis	analyzed the data and contributed to the statistical analysis	Analyzed the data	Formal analysis	YES
6419926	30996981	H.K.K.S.	2	contributed equally to this work	contributed equally to this work	-	-	NO
6419926	30996981	K.J.C.	2	contributed equally to this work	contributed equally to this work	-	-	NO
5816812	29487608	AA	2	were involved in generation of transgenics and completed molecular analysis	were involved in generation of transgenics and completed molecular analysis	Performed the experiments	Investigation	YES
5816812	29487608	BB	2	were involved in generation of transgenics and completed molecular analysis	were involved in generation of transgenics and completed molecular analysis	Performed the experiments	Investigation	YES
5816812	29487608	BR	2	helped in physiological analysis of transgenic plants	helped in physiological analysis of transgenic plants	Performed the experiments	Investigation	YES
5816812	29487608	DF	2	conceived the idea and designed all the experiments|were involved in generation of transgenics and completed molecular analysis|helped in physiological analysis of transgenic plants|assisted in molecular analysis|critically analyzed the data and wrote the manuscript	conceived the idea and designed all the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5816812	29487608	DF	2	conceived the idea and designed all the experiments|were involved in generation of transgenics and completed molecular analysis|helped in physiological analysis of transgenic plants|assisted in molecular analysis|critically analyzed the data and wrote the manuscript	were involved in generation of transgenics and completed molecular analysis	Performed the experiments	Investigation	YES
5816812	29487608	DF	2	conceived the idea and designed all the experiments|were involved in generation of transgenics and completed molecular analysis|helped in physiological analysis of transgenic plants|assisted in molecular analysis|critically analyzed the data and wrote the manuscript	helped in physiological analysis of transgenic plants	Performed the experiments	Investigation	YES
5816812	29487608	DF	2	conceived the idea and designed all the experiments|were involved in generation of transgenics and completed molecular analysis|helped in physiological analysis of transgenic plants|assisted in molecular analysis|critically analyzed the data and wrote the manuscript	assisted in molecular analysis	Performed the experiments	Investigation	YES
5816812	29487608	DF	2	conceived the idea and designed all the experiments|were involved in generation of transgenics and completed molecular analysis|helped in physiological analysis of transgenic plants|assisted in molecular analysis|critically analyzed the data and wrote the manuscript	critically analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5816812	29487608	DJ	2	were involved in generation of transgenics and completed molecular analysis	were involved in generation of transgenics and completed molecular analysis	Performed the experiments	Investigation	YES
5816812	29487608	MM	2	helped in physiological analysis of transgenic plants	helped in physiological analysis of transgenic plants	Performed the experiments	Investigation	YES
5816812	29487608	MR	2	conceived the idea and designed all the experiments|critically analyzed the data and wrote the manuscript	conceived the idea and designed all the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5816812	29487608	MR	2	conceived the idea and designed all the experiments|critically analyzed the data and wrote the manuscript	critically analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5816812	29487608	PV	2	assisted in molecular analysis	assisted in molecular analysis	Performed the experiments	Investigation	YES
5816812	29487608	RY	2	assisted in molecular analysis	assisted in molecular analysis	Performed the experiments	Investigation	YES
5816812	29487608	VA	2	critically analyzed the data and wrote the manuscript	critically analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5816812	29487608	VS	2	helped in physiological analysis of transgenic plants	helped in physiological analysis of transgenic plants	Performed the experiments	Investigation	YES
5773145	29343217	TEs	2	rip analysis	rip analysis	-	-	NO
3428963	22688295	CH	2	underlying study design	underlying study design	Conceived and designed the experiments	Methodology	YES
3428963	22688295	DM	2	underlying study design|animal experiments conduction|data analysis and manuscript writing	underlying study design	Conceived and designed the experiments	Methodology	YES
3428963	22688295	DM	2	underlying study design|animal experiments conduction|data analysis and manuscript writing	animal experiments conduction	Performed the experiments	Investigation	YES
3428963	22688295	DM	2	underlying study design|animal experiments conduction|data analysis and manuscript writing	data analysis and manuscript writing	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3428963	22688295	DS	2	funding facilitation	funding facilitation	-	Funding acquisition	YES
3428963	22688295	FL	2	tissue preparation and serial staining performing	tissue preparation and serial staining performing	Performed the experiments	Investigation	YES
3428963	22688295	JB	2	underlying study design|manuscript critical revision	underlying study design	Conceived and designed the experiments	Methodology	YES
3428963	22688295	JB	2	underlying study design|manuscript critical revision	manuscript critical revision	Wrote the paper	Writing - Review & Editing	YES
3428963	22688295	JG	2	laser scanning microscopy	laser scanning microscopy	Performed the experiments	Investigation	YES
3428963	22688295	JK	2	semiquantitative analyses	semiquantitative analyses	Analyzed the data	Formal analysis	YES
3428963	22688295	LKT	2	underlying study design|animal experiments conduction	underlying study design	Conceived and designed the experiments	Methodology	YES
3428963	22688295	LKT	2	underlying study design|animal experiments conduction	animal experiments conduction	Performed the experiments	Investigation	YES
3428963	22688295	MH	2	tissue preparation and serial staining performing|manuscript critical revision	tissue preparation and serial staining performing	Performed the experiments	Investigation	YES
3428963	22688295	MH	2	tissue preparation and serial staining performing|manuscript critical revision	manuscript critical revision	Wrote the paper	Writing - Review & Editing	YES
3428963	22688295	ML	2	manuscript critical revision	manuscript critical revision	Wrote the paper	Writing - Review & Editing	YES
3428963	22688295	WH	2	tissue preparation and serial staining performing|manuscript critical revision	tissue preparation and serial staining performing	Performed the experiments	Investigation	YES
3428963	22688295	WH	2	tissue preparation and serial staining performing|manuscript critical revision	manuscript critical revision	Wrote the paper	Writing - Review & Editing	YES
5052750	27672157	Victor de Lorenzo	2	for stimulating discussions and advice throughout the work	for stimulating discussions and advice throughout the work	-	-	NO
1978522	17895995	AC	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1978522	17895995	AG	PLoS5	Analyzed the data|Programmers	Analyzed the data	Analyzed the data	Formal analysis	YES
1978522	17895995	AG	PLoS5	Analyzed the data|Programmers	Programmers	Contributed reagents/materials/analysis tools	Software	YES
1978522	17895995	AL	PLoS5	Conceived and designed the experiments|Analyzed the data|Genome-sequencing project coordinator	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1978522	17895995	AL	PLoS5	Conceived and designed the experiments|Analyzed the data|Genome-sequencing project coordinator	Analyzed the data	Analyzed the data	Formal analysis	YES
1978522	17895995	AL	PLoS5	Conceived and designed the experiments|Analyzed the data|Genome-sequencing project coordinator	Genome-sequencing project coordinator	Performed the experiments	Investigation|Project administration	YES
1978522	17895995	AS	PLoS5	Analyzed the data|Programmers	Analyzed the data	Analyzed the data	Formal analysis	YES
1978522	17895995	AS	PLoS5	Analyzed the data|Programmers	Programmers	Contributed reagents/materials/analysis tools	Software	YES
1978522	17895995	AV	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1978522	17895995	BL	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1978522	17895995	BL	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1978522	17895995	BR	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1978522	17895995	BR	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1978522	17895995	CD	PLoS5	Performed the experiments|Analyzed the data|Library construction	Performed the experiments	Performed the experiments	Investigation	YES
1978522	17895995	CD	PLoS5	Performed the experiments|Analyzed the data|Library construction	Analyzed the data	Analyzed the data	Formal analysis	YES
1978522	17895995	CD	PLoS5	Performed the experiments|Analyzed the data|Library construction	Library construction	Performed the experiments	Investigation	YES
1978522	17895995	EG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1978522	17895995	EG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1978522	17895995	EG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1978522	17895995	EK	PLoS5	Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed to writing the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1978522	17895995	EK	PLoS5	Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed to writing the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1978522	17895995	EK	PLoS5	Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed to writing the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1978522	17895995	EK	PLoS5	Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed to writing the paper	Contributed to writing the paper	Wrote the paper	Writing - Original Draft	YES
1978522	17895995	ES	PLoS5	Performed the experiments|Analyzed the data|Genome finishing	Performed the experiments	Performed the experiments	Investigation	YES
1978522	17895995	ES	PLoS5	Performed the experiments|Analyzed the data|Genome finishing	Analyzed the data	Analyzed the data	Formal analysis	YES
1978522	17895995	ES	PLoS5	Performed the experiments|Analyzed the data|Genome finishing	Genome finishing	-	-	NO
1978522	17895995	JF	PLoS5	Analyzed the data|Programmers	Analyzed the data	Analyzed the data	Formal analysis	YES
1978522	17895995	JF	PLoS5	Analyzed the data|Programmers	Programmers	Contributed reagents/materials/analysis tools	Software	YES
1978522	17895995	JGI	PLoS5	Other	Other	-	-	NO
1978522	17895995	KK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1978522	17895995	KK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1978522	17895995	KK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1978522	17895995	KM	PLoS5	Conceived and designed the experiments|Analyzed the data|Analyzed the data|Wrote the paper|Genome annotation	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1978522	17895995	KM	PLoS5	Conceived and designed the experiments|Analyzed the data|Analyzed the data|Wrote the paper|Genome annotation	Analyzed the data	Analyzed the data	Formal analysis	YES
1978522	17895995	KM	PLoS5	Conceived and designed the experiments|Analyzed the data|Analyzed the data|Wrote the paper|Genome annotation	Analyzed the data	Analyzed the data	Formal analysis	YES
1978522	17895995	KM	PLoS5	Conceived and designed the experiments|Analyzed the data|Analyzed the data|Wrote the paper|Genome annotation	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1978522	17895995	KM	PLoS5	Conceived and designed the experiments|Analyzed the data|Analyzed the data|Wrote the paper|Genome annotation	Genome annotation	Analyzed the data	Data curation|Formal analysis	YES
1978522	17895995	MD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1978522	17895995	MD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1978522	17895995	MD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1978522	17895995	MG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1978522	17895995	MG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1978522	17895995	ML	PLoS5	Analyzed the data|Genome annotation	Analyzed the data	Analyzed the data	Formal analysis	YES
1978522	17895995	ML	PLoS5	Analyzed the data|Genome annotation	Genome annotation	Analyzed the data	Data curation|Formal analysis	YES
1978522	17895995	MO	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1978522	17895995	MZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1978522	17895995	PR	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1978522	17895995	SP	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1978522	17895995	TB	PLoS5	Performed the experiments|Analyzed the data|Genome finishing	Performed the experiments	Performed the experiments	Investigation	YES
1978522	17895995	TB	PLoS5	Performed the experiments|Analyzed the data|Genome finishing	Analyzed the data	Analyzed the data	Formal analysis	YES
1978522	17895995	TB	PLoS5	Performed the experiments|Analyzed the data|Genome finishing	Genome finishing	-	-	NO
1978522	17895995	VM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1978522	17895995	VM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1978522	17895995	VM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1978522	17895995	YW	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416928	25933431	BC	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416928	25933431	MV	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416928	25933431	PB	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416928	25933431	PB	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416928	25933431	SG	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416928	25933431	SR	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416928	25933431	SS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416928	25933431	SS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416928	25933431	SZ	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5816897	29487610	HY	PLoS52	contributed analytic tools and perl scripts	contributed analytic tools and perl scripts	Contributed reagents/materials/analysis tools	Resources|Software	YES
5816897	29487610	JW	PLoS52	contributed advice	contributed advice	-	-	NO
5816897	29487610	JyW	PLoS52	contributed advice	contributed advice	-	-	NO
5816897	29487610	LL	PLoS52	contributed analytic tools and perl scripts	contributed analytic tools and perl scripts	Contributed reagents/materials/analysis tools	Resources|Software	YES
5816897	29487610	RW	PLoS52	contributed analytic tools and perl scripts	contributed analytic tools and perl scripts	Contributed reagents/materials/analysis tools	Resources|Software	YES
5816897	29487610	SZ	PLoS52	conceived and designed the experiments|managed the research and experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5816897	29487610	SZ	PLoS52	conceived and designed the experiments|managed the research and experiments	managed the research and experiments	-	-	NO
5816897	29487610	XQ	PLoS52	conceived and designed the experiments|carried out the experimental design, data analysis, and drafted the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5816897	29487610	XQ	PLoS52	conceived and designed the experiments|carried out the experimental design, data analysis, and drafted the manuscript	carried out the experimental design, data analysis, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
3491822	22767443	AB	2	conceived the hypothesis, designed experiments and wrote the manuscript	conceived the hypothesis, designed experiments and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
3491822	22767443	CJA	2	performed and analyzed the lipidomics studies	performed and analyzed the lipidomics studies	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3491822	22767443	DAF	2	performed and analyzed the lipidomics studies	performed and analyzed the lipidomics studies	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3491822	22767443	DQ-HW	2	performed common bile duct cannulations for secretion experiments	performed common bile duct cannulations for secretion experiments	Performed the experiments	Investigation	YES
3491822	22767443	FJS	2	performed mrna experiments in huh-7 cells	performed mrna experiments in huh-7 cells	Performed the experiments	Investigation	YES
3491822	22767443	MA	2	performed mrna experiments in huh-7 cells	performed mrna experiments in huh-7 cells	Performed the experiments	Investigation	YES
3491822	22767443	RMA	2	conceived the hypothesis, designed and performed experiments, analyzed the data and wrote the manuscript|performed and analyzed the lipidomics studies	conceived the hypothesis, designed and performed experiments, analyzed the data and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
3491822	22767443	RMA	2	conceived the hypothesis, designed and performed experiments, analyzed the data and wrote the manuscript|performed and analyzed the lipidomics studies	performed and analyzed the lipidomics studies	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3491822	22767443	TJM	2	designed, performed and analyzed the rct experiment	designed, performed and analyzed the rct experiment	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5794715	29392444	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5794715	29392444	CX	2	took part in the design of experiments and experimentation	took part in the design of experiments and experimentation	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5794715	29392444	JM	2	is corresponding author and is responsible for the whole process of experimentation and manuscript subscription	is corresponding author and is responsible for the whole process of experimentation and manuscript subscription	Performed the experiments	Investigation	YES
5794715	29392444	QD	2	wrote this manuscript and participated in all the experiments	wrote this manuscript and participated in all the experiments	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5794715	29392444	YG	2	took part in the design of experiments and experimentation	took part in the design of experiments and experimentation	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5794715	29392444	YL	2	took part in the design of experiments and experimentation	took part in the design of experiments and experimentation	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5062094	28080963	C.A.	PLoS52	provided clinical and anatomical expertise	provided clinical and anatomical expertise	-	-	NO
5062094	28080963	C.T.-B.	PLoS52	designed the experiment|analysed the data|wrote the paper	designed the experiment	Conceived and designed the experiments	Methodology	YES
5062094	28080963	C.T.-B.	PLoS52	designed the experiment|analysed the data|wrote the paper	analysed the data	Analyzed the data	Formal analysis	YES
5062094	28080963	C.T.-B.	PLoS52	designed the experiment|analysed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5062094	28080963	D.H.	PLoS52	provided clinical and anatomical expertise	provided clinical and anatomical expertise	-	-	NO
5062094	28080963	M.B.-R.	PLoS52	designed the experiment|acquired the data|analysed the data|wrote the paper	designed the experiment	Conceived and designed the experiments	Methodology	YES
5062094	28080963	M.B.-R.	PLoS52	designed the experiment|acquired the data|analysed the data|wrote the paper	acquired the data	Performed the experiments	Investigation	YES
5062094	28080963	M.B.-R.	PLoS52	designed the experiment|acquired the data|analysed the data|wrote the paper	analysed the data	Analyzed the data	Formal analysis	YES
5062094	28080963	M.B.-R.	PLoS52	designed the experiment|acquired the data|analysed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5062094	28080963	N.W.	PLoS52	analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
4416929	25933218	GXC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416929	25933218	LD	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416929	25933218	RYX	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416929	25933218	SC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416929	25933218	SQW	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4416929	25933218	SQW	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416929	25933218	SZ	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416929	25933218	SZ	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416929	25933218	TTH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416929	25933218	TTH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416929	25933218	TTH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416929	25933218	WQT	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4416929	25933218	WQT	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416929	25933218	XZS	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416929	25933218	YC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
6270770	24815311	Huixia Lv	7	Gave technical support and advice	Gave technical support and advice	Performed the experiments	Investigation	YES
6270770	24815311	Jianping Zhou	7	Designed the experiments and revised the manuscript	Designed the experiments and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
6270770	24815311	Jumah Masoud	7	Performed the experiments and prepared the manuscript	Performed the experiments and prepared the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6270770	24815311	M. Salmani	7	Performed the experiments and prepared the manuscript	Performed the experiments and prepared the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6270770	24815311	Sajid Asghar	7	Analyzed the data and helped in preparing the manuscript	Analyzed the data and helped in preparing the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3428964	22688296	CZ	2	execution of experiments|design of experiments and writing	execution of experiments	Performed the experiments	Investigation	YES
3428964	22688296	CZ	2	execution of experiments|design of experiments and writing	design of experiments and writing	Conceived and designed the experiments|Wrote the paper	Methodology	YES
3428964	22688296	FT	2	execution of experiments	execution of experiments	Performed the experiments	Investigation	YES
3428964	22688296	JCP	2	design of experiments and writing	design of experiments and writing	Conceived and designed the experiments|Wrote the paper	Methodology	YES
3428964	22688296	MC	2	execution of experiments	execution of experiments	Performed the experiments	Investigation	YES
3428964	22688296	TMS	2	design of experiments and writing	design of experiments and writing	Conceived and designed the experiments|Wrote the paper	Methodology	YES
5773867	29219084	CW	2	conceived and planed the research|reviewed and edited the manuscript	conceived and planed the research	Conceived and designed the experiments	Conceptualization	YES
5773867	29219084	CW	2	conceived and planed the research|reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5773867	29219084	LW	2	conceived and planed the research	conceived and planed the research	Conceived and designed the experiments	Conceptualization	YES
5773867	29219084	LX	2	conceived and planed the research|designed and carried out the comparative study, wrote the code, and drafted the manuscript|reviewed and edited the manuscript	conceived and planed the research	Conceived and designed the experiments	Conceptualization	YES
5773867	29219084	LX	2	conceived and planed the research|designed and carried out the comparative study, wrote the code, and drafted the manuscript|reviewed and edited the manuscript	designed and carried out the comparative study, wrote the code, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Software|Writing - Original Draft	YES
5773867	29219084	LX	2	conceived and planed the research|designed and carried out the comparative study, wrote the code, and drafted the manuscript|reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5773867	29219084	MG	2	conceived and planed the research|reviewed and edited the manuscript	conceived and planed the research	Conceived and designed the experiments	Conceptualization	YES
5773867	29219084	MG	2	conceived and planed the research|reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5773867	29219084	XL	2	conceived and planed the research|reviewed and edited the manuscript	conceived and planed the research	Conceived and designed the experiments	Conceptualization	YES
5773867	29219084	XL	2	conceived and planed the research|reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5773867	29219084	YZ	2	conceived and planed the research	conceived and planed the research	Conceived and designed the experiments	Conceptualization	YES
1978523	17895975	AK	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1978523	17895975	AK	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1978523	17895975	ED	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1978523	17895975	ED	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1978523	17895975	ED	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1978523	17895975	ED	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1978523	17895975	MM	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1978523	17895975	MM	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3491823	22887866	AALT	2	designed and performed the experiments with|analyzed data|prepared the manuscript	designed and performed the experiments with	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3491823	22887866	AALT	2	designed and performed the experiments with|analyzed data|prepared the manuscript	analyzed data	Analyzed the data	Formal analysis	YES
3491823	22887866	AALT	2	designed and performed the experiments with|analyzed data|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
3491823	22887866	AKP	2	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
3491823	22887866	JZ	2	helped with the designed and performed the experiments with	helped with the designed and performed the experiments with	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3491823	22887866	KHY	2	designed and performed the experiments with	designed and performed the experiments with	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3491823	22887866	LEBB	2	designed and performed the experiments with|analyzed data	designed and performed the experiments with	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3491823	22887866	LEBB	2	designed and performed the experiments with|analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
3491823	22887866	ML	2	designed and performed the experiments with	designed and performed the experiments with	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3491823	22887866	RCGM	2	designed and performed the experiments with	designed and performed the experiments with	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3491823	22887866	SC	2	helped with the designed and performed the experiments with	helped with the designed and performed the experiments with	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3491823	22887866	W-YP	2	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
3491823	22887866	YaL	2	designed and performed the experiments with|analyzed data	designed and performed the experiments with	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3491823	22887866	YaL	2	designed and performed the experiments with|analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
3491823	22887866	YoL	2	designed and performed the experiments with|analyzed data|prepared the manuscript	designed and performed the experiments with	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3491823	22887866	YoL	2	designed and performed the experiments with|analyzed data|prepared the manuscript	analyzed data	Analyzed the data	Formal analysis	YES
3491823	22887866	YoL	2	designed and performed the experiments with|analyzed data|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
3491823	22887866	all authors	2	discussed the results and commented on the manuscript	discussed the results and commented on the manuscript	-	-	NO
5816898	29487607	AM	2	developed the analysis method applied in the experiment and helped the analysis of extracts from plant samples	developed the analysis method applied in the experiment and helped the analysis of extracts from plant samples	Performed the experiments	Investigation|Methodology	YES
5816898	29487607	M. All	2	authors discussed the results and contributed to the final manuscript	authors discussed the results and contributed to the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5816898	29487607	RS	2	supervised the ph|carried out the experiment	supervised the ph	-	Supervision	YES
5816898	29487607	RS	2	supervised the ph|carried out the experiment	carried out the experiment	Performed the experiments	Investigation	YES
5816898	29487607	ST	2	supervised the ph|carried out the experiment	supervised the ph	-	Supervision	YES
5816898	29487607	ST	2	supervised the ph|carried out the experiment	carried out the experiment	Performed the experiments	Investigation	YES
4416930	25932650	BL	PLoS5	Performed the experiments|Read and approved the final manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4416930	25932650	BL	PLoS5	Performed the experiments|Read and approved the final manuscript	Read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4416930	25932650	ED	PLoS5	Constructed the database|Read and approved the final manuscript	Constructed the database	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
4416930	25932650	ED	PLoS5	Constructed the database|Read and approved the final manuscript	Read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4416930	25932650	FM	PLoS5	Constructed the database|Read and approved the final manuscript	Constructed the database	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
4416930	25932650	FM	PLoS5	Constructed the database|Read and approved the final manuscript	Read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4416930	25932650	SW	PLoS5	Performed the experiments|Wrote the paper|Read and approved the final manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4416930	25932650	SW	PLoS5	Performed the experiments|Wrote the paper|Read and approved the final manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416930	25932650	SW	PLoS5	Performed the experiments|Wrote the paper|Read and approved the final manuscript	Read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4416930	25932650	WJ	PLoS5	Conceived and designed the experiments|Read and approved the final manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416930	25932650	WJ	PLoS5	Conceived and designed the experiments|Read and approved the final manuscript	Read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4416930	25932650	WL	PLoS5	Performed the experiments|Read and approved the final manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4416930	25932650	WL	PLoS5	Performed the experiments|Read and approved the final manuscript	Read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4416930	25932650	X. Li	PLoS5	Conceived and designed the experiments|Read and approved the final manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416930	25932650	X. Li	PLoS5	Conceived and designed the experiments|Read and approved the final manuscript	Read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4416930	25932650	X. Liu	PLoS5	Collected data sets|Read and approved the final manuscript	Collected data sets	Performed the experiments	Investigation	YES
4416930	25932650	X. Liu	PLoS5	Collected data sets|Read and approved the final manuscript	Read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4416930	25932650	XY	PLoS5	Constructed the database|Read and approved the final manuscript	Constructed the database	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
4416930	25932650	XY	PLoS5	Constructed the database|Read and approved the final manuscript	Read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4416930	25932650	YZ	PLoS5	Collected data sets|Read and approved the final manuscript	Collected data sets	Performed the experiments	Investigation	YES
4416930	25932650	YZ	PLoS5	Collected data sets|Read and approved the final manuscript	Read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5799089	29404802	AN	PLoS52	carried out experiments	carried out experiments	Performed the experiments	Investigation	YES
5799089	29404802	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5799089	29404802	BS	PLoS52	carried out experiments|analysed the data|reviewed and revised manuscript	carried out experiments	Performed the experiments	Investigation	YES
5799089	29404802	BS	PLoS52	carried out experiments|analysed the data|reviewed and revised manuscript	analysed the data	Analyzed the data	Formal analysis	YES
5799089	29404802	BS	PLoS52	carried out experiments|analysed the data|reviewed and revised manuscript	reviewed and revised manuscript	Wrote the paper	Writing - Review & Editing	YES
5799089	29404802	IB	PLoS52	carried out experiments|reviewed and revised manuscript	carried out experiments	Performed the experiments	Investigation	YES
5799089	29404802	IB	PLoS52	carried out experiments|reviewed and revised manuscript	reviewed and revised manuscript	Wrote the paper	Writing - Review & Editing	YES
5799089	29404802	IS	PLoS52	conceived and designed experiments|analysed the data|reviewed and revised manuscript	conceived and designed experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5799089	29404802	IS	PLoS52	conceived and designed experiments|analysed the data|reviewed and revised manuscript	analysed the data	Analyzed the data	Formal analysis	YES
5799089	29404802	IS	PLoS52	conceived and designed experiments|analysed the data|reviewed and revised manuscript	reviewed and revised manuscript	Wrote the paper	Writing - Review & Editing	YES
5799089	29404802	Josip Juraj Strossmayer	PLoS52	for providing research facilities	for providing research facilities	-	-	NO
5799089	29404802	MK	PLoS52	carried out experiments|reviewed and revised manuscript	carried out experiments	Performed the experiments	Investigation	YES
5799089	29404802	MK	PLoS52	carried out experiments|reviewed and revised manuscript	reviewed and revised manuscript	Wrote the paper	Writing - Review & Editing	YES
5799089	29404802	TK	PLoS52	conceived and designed experiments|carried out experiments|analysed the data|analysed the data|wrote the manuscript|reviewed and revised manuscript	conceived and designed experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5799089	29404802	TK	PLoS52	conceived and designed experiments|carried out experiments|analysed the data|analysed the data|wrote the manuscript|reviewed and revised manuscript	carried out experiments	Performed the experiments	Investigation	YES
5799089	29404802	TK	PLoS52	conceived and designed experiments|carried out experiments|analysed the data|analysed the data|wrote the manuscript|reviewed and revised manuscript	analysed the data	Analyzed the data	Formal analysis	YES
5799089	29404802	TK	PLoS52	conceived and designed experiments|carried out experiments|analysed the data|analysed the data|wrote the manuscript|reviewed and revised manuscript	analysed the data	Analyzed the data	Formal analysis	YES
5799089	29404802	TK	PLoS52	conceived and designed experiments|carried out experiments|analysed the data|analysed the data|wrote the manuscript|reviewed and revised manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5799089	29404802	TK	PLoS52	conceived and designed experiments|carried out experiments|analysed the data|analysed the data|wrote the manuscript|reviewed and revised manuscript	reviewed and revised manuscript	Wrote the paper	Writing - Review & Editing	YES
5799089	29404802	The authors	PLoS52	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
1978524	17895976	AR	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1978524	17895976	MP	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1978524	17895976	MP	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1978524	17895976	MP	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1978524	17895976	RB	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1978524	17895976	RB	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1978524	17895976	SZ	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1978524	17895976	SZ	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1978524	17895976	TH	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1978524	17895976	TH	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1978524	17895976	UB	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1978524	17895976	UB	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5062095	28080964	All authors	2	revised the manuscript and gave final approval for publication	revised the manuscript and gave final approval for publication	Wrote the paper	Writing - Review & Editing	YES
5773891	29219079	IM	2	designed the study and wrote the paper	designed the study and wrote the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5773891	29219079	LJ	2	designed the study and wrote the paper|developed the computational method	designed the study and wrote the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5773891	29219079	LJ	2	designed the study and wrote the paper|developed the computational method	developed the computational method	Performed the experiments	Formal analysis|Methodology	YES
5773891	29219079	LL	2	helped in designing the statistical parts of the method	helped in designing the statistical parts of the method	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Methodology	YES
4416931	25933096	LL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416931	25933096	LL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4416931	25933096	LL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416931	25933096	MN	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4416931	25933096	MN	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416931	25933096	MPC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416931	25933096	MPC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416931	25933096	MPC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416931	25933096	SL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416931	25933096	TEA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416931	25933096	TEA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416931	25933096	TEA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416931	25933096	TEA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3491824	22915554	CH	2	participated in the fiber type analyses	participated in the fiber type analyses	Analyzed the data	Formal analysis	YES
3491824	22915554	DS	2	designed and analysed the experiments and wrote the manuscript	designed and analysed the experiments and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3491824	22915554	GM	2	designed and analysed the experiments and wrote the manuscript	designed and analysed the experiments and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3491824	22915554	HA	2	participated in the fiber type analyses	participated in the fiber type analyses	Analyzed the data	Formal analysis	YES
3491824	22915554	ND	2	designed and analysed the experiments and wrote the manuscript	designed and analysed the experiments and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3428966	22688298	all authors	2	contributed equally to the work	contributed equally to the work	-	-	NO
1978525	17895987	BL	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1978525	17895987	BL	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1978525	17895987	PE	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1978525	17895987	PE	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1978525	17895987	PE	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1978525	17895987	YS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1978525	17895987	YS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1978525	17895987	YS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5816925	29487612	JH	2	revised and edited the manuscript and also provided advice on the experiments	revised and edited the manuscript and also provided advice on the experiments	Wrote the paper	Writing - Review & Editing	YES
5816925	29487612	KC	2	revised and edited the manuscript and also provided advice on the experiments	revised and edited the manuscript and also provided advice on the experiments	Wrote the paper	Writing - Review & Editing	YES
5816925	29487612	SP	2	revised and edited the manuscript and also provided advice on the experiments	revised and edited the manuscript and also provided advice on the experiments	Wrote the paper	Writing - Review & Editing	YES
6270772	25389661	I Kashchenko	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270772	25389661	K Chirikova	PLoS52	performed research and analyzed the data	performed research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270772	25389661	N Olennikov	PLoS52	designed research	designed research	Conceived and designed the experiments	Methodology	YES
5062098	28080967	A.F.	PLoS52	designed the study|wrote the paper	designed the study	Conceived and designed the experiments	Methodology	YES
5062098	28080967	A.F.	PLoS52	designed the study|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5062098	28080967	C.K.	PLoS52	designed the study|ran the study and analysed the results|wrote the paper	designed the study	Conceived and designed the experiments	Methodology	YES
5062098	28080967	C.K.	PLoS52	designed the study|ran the study and analysed the results|wrote the paper	ran the study and analysed the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5062098	28080967	C.K.	PLoS52	designed the study|ran the study and analysed the results|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5062098	28080967	M.D.	PLoS52	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5062098	28080967	Y.P.	PLoS52	designed the study|wrote the paper	designed the study	Conceived and designed the experiments	Methodology	YES
5062098	28080967	Y.P.	PLoS52	designed the study|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5805669	29423882	Both authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5805669	29423882	JZ	PLoS52	conceived the method and designed the experiments|performed the experiments|analyzed the results|wrote the manuscript	conceived the method and designed the experiments	Conceived and designed the experiments|Performed the experiments	Conceptualization|Methodology	YES
5805669	29423882	JZ	PLoS52	conceived the method and designed the experiments|performed the experiments|analyzed the results|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5805669	29423882	JZ	PLoS52	conceived the method and designed the experiments|performed the experiments|analyzed the results|wrote the manuscript	analyzed the results	Analyzed the data	Formal analysis	YES
5805669	29423882	JZ	PLoS52	conceived the method and designed the experiments|performed the experiments|analyzed the results|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5805669	29423882	MW	PLoS52	conceived the method and designed the experiments|analyzed the results|wrote the manuscript	conceived the method and designed the experiments	Conceived and designed the experiments|Performed the experiments	Conceptualization|Methodology	YES
5805669	29423882	MW	PLoS52	conceived the method and designed the experiments|analyzed the results|wrote the manuscript	analyzed the results	Analyzed the data	Formal analysis	YES
5805669	29423882	MW	PLoS52	conceived the method and designed the experiments|analyzed the results|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5805669	29423882	The authors	PLoS52	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
3491825	22821840	EJL	2	interpreted data	interpreted data	Analyzed the data	Formal analysis	YES
3491825	22821840	HKJ	2	performed experiments and analysed data	performed experiments and analysed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3491825	22821840	HSK	2	interpreted data and wrote the manuscript	interpreted data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3491825	22821840	JL	2	performed mouse hindlimb ischemia experiment	performed mouse hindlimb ischemia experiment	Performed the experiments	Investigation	YES
3491825	22821840	JML	2	interpreted data	interpreted data	Analyzed the data	Formal analysis	YES
3491825	22821840	JWP	2	interpreted data	interpreted data	Analyzed the data	Formal analysis	YES
3491825	22821840	JY	2	performed experiments and analysed data	performed experiments and analysed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3491825	22821840	JYL	2	performed experiments and analysed data	performed experiments and analysed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3491825	22821840	KWK	2	for plasmid construction	for plasmid construction	Performed the experiments	Investigation	YES
3491825	22821840	SWL	2	designed the research, interpreted data and wrote the manuscript	designed the research, interpreted data and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3491825	22821840	SWY	2	performed mouse hindlimb ischemia experiment	performed mouse hindlimb ischemia experiment	Performed the experiments	Investigation	YES
3491825	22821840	SYK	2	performed experiments and analysed data	performed experiments and analysed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3491825	22821840	WJK	2	for plasmid construction	for plasmid construction	Performed the experiments	Investigation	YES
3491825	22821840	YBP	2	interpreted data and wrote the manuscript	interpreted data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5062109	28080978	All the authors	2	contributed equally	contributed equally	-	-	NO
3428967	22688299	HKa	2	study design, coordination, cell and rat experiments planning and carrying out, manuscript drafting	study design, coordination, cell and rat experiments planning and carrying out, manuscript drafting	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Project administration|Writing - Original Draft	YES
3428967	22688299	HKo	2	study design, coordination, cell and rat experiments planning and carrying out, manuscript drafting	study design, coordination, cell and rat experiments planning and carrying out, manuscript drafting	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Project administration|Writing - Original Draft	YES
3428967	22688299	JJH	2	mouse protein studies carrying out	mouse protein studies carrying out	Performed the experiments	Investigation	YES
3428967	22688299	PR	2	mouse microscopy	mouse microscopy	Performed the experiments	Investigation	YES
5816928	29487611	BX	PLoS52	conceived and designed the experiments|contributed reagents/materials/analysis tools|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5816928	29487611	BX	PLoS52	conceived and designed the experiments|contributed reagents/materials/analysis tools|wrote the paper	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5816928	29487611	BX	PLoS52	conceived and designed the experiments|contributed reagents/materials/analysis tools|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5816928	29487611	JP	PLoS52	analyzed the data|contributed reagents/materials/analysis tools	analyzed the data	Analyzed the data	Formal analysis	YES
5816928	29487611	JP	PLoS52	analyzed the data|contributed reagents/materials/analysis tools	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5816928	29487611	WX	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5816928	29487611	WX	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5816928	29487611	YC	PLoS52	conceived and designed the experiments|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5816928	29487611	YC	PLoS52	conceived and designed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5816928	29487611	ZC	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5816928	29487611	ZC	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5816928	29487611	ZW	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5816928	29487611	ZW	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
4416932	25933416	AM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416932	25933416	DT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416932	25933416	DT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416932	25933416	DT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416932	25933416	DT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416932	25933416	EB	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4416932	25933416	EB	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416932	25933416	LG	PLoS5	Provided crucial suggestions about the experiments	Provided crucial suggestions about the experiments	-	-	NO
4416932	25933416	MJ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416932	25933416	ML	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4416932	25933416	ML	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416932	25933416	MO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416932	25933416	MO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416932	25933416	MO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416932	25933416	MO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416932	25933416	NC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416932	25933416	NC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416932	25933416	NC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416932	25933416	NC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416932	25933416	NO	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Provided crucial suggestions about the experiments	Analyzed the data	Analyzed the data	Formal analysis	YES
4416932	25933416	NO	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Provided crucial suggestions about the experiments	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416932	25933416	NO	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Provided crucial suggestions about the experiments	Provided crucial suggestions about the experiments	-	-	NO
4416932	25933416	SF	PLoS5	Contributed reagents/materials/analysis tools|Provided crucial suggestions about the experiments	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416932	25933416	SF	PLoS5	Contributed reagents/materials/analysis tools|Provided crucial suggestions about the experiments	Provided crucial suggestions about the experiments	-	-	NO
4416932	25933416	SL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416932	25933416	SL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416932	25933416	SL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416932	25933416	SL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416932	25933416	TNG	PLoS5	Provided crucial suggestions about the experiments	Provided crucial suggestions about the experiments	-	-	NO
4416932	25933416	TS	PLoS5	Performed the experiments|Provided crucial suggestions about the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416932	25933416	TS	PLoS5	Performed the experiments|Provided crucial suggestions about the experiments	Provided crucial suggestions about the experiments	-	-	NO
4416932	25933416	TVG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416932	25933416	TVG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416932	25933416	TVG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416932	25933416	TVG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5773895	29219072	AQ	2	interpreted the results and wrote the manuscript	interpreted the results and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5773895	29219072	JC	2	contributed to the design of the study|interpreted the results and wrote the manuscript	contributed to the design of the study	Conceived and designed the experiments	Methodology	YES
5773895	29219072	JC	2	contributed to the design of the study|interpreted the results and wrote the manuscript	interpreted the results and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5773895	29219072	JW	2	interpreted the results and wrote the manuscript	interpreted the results and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5773895	29219072	RX	2	implemented the framework|interpreted the results and wrote the manuscript	implemented the framework	Performed the experiments	Investigation	YES
5773895	29219072	RX	2	implemented the framework|interpreted the results and wrote the manuscript	interpreted the results and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5773895	29219072	XS	2	contributed to the design of the study|interpreted the results and wrote the manuscript	contributed to the design of the study	Conceived and designed the experiments	Methodology	YES
5773895	29219072	XS	2	contributed to the design of the study|interpreted the results and wrote the manuscript	interpreted the results and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6270773	25383754	F.J.	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
6270773	25383754	J.-S.S.	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6270773	25383754	J.-S.S.	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
6270773	25383754	J.L.	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6270773	25383754	J.L.	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
6270773	25383754	J.L.	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
6270773	25383754	J.L.	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270773	25383754	Q.W.	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
6270773	25383754	Y.-F.L.	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6270773	25383754	Y.-F.L.	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
6270773	25383754	Y.-F.L.	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
6270773	25383754	Y.-F.L.	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270773	25383754	Y.-Y.X.	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
6270773	25383754	Y.-Y.X.	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
6270773	25383754	Y.-Y.X.	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1978526	17895997	DL	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Analyzed the data|Analyzed the data|Wrote the paper|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1978526	17895997	DL	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Analyzed the data|Analyzed the data|Wrote the paper|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1978526	17895997	DL	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Analyzed the data|Analyzed the data|Wrote the paper|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1978526	17895997	DL	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Analyzed the data|Analyzed the data|Wrote the paper|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1978526	17895997	DL	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Analyzed the data|Analyzed the data|Wrote the paper|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1978526	17895997	DL	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Analyzed the data|Analyzed the data|Wrote the paper|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1978526	17895997	HE	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1978526	17895997	HE	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1978526	17895997	LB	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1978526	17895997	LB	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1978526	17895997	MC	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1978526	17895997	MC	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1978526	17895997	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1978526	17895997	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1978526	17895997	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1978526	17895997	MG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1978526	17895997	TR	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1978526	17895997	TR	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5809631	29435681	ACP	2	supervised the work and were involved in the correction of the final version of the manuscript	supervised the work and were involved in the correction of the final version of the manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
5809631	29435681	CS	2	supervised the work and were involved in the correction of the final version of the manuscript	supervised the work and were involved in the correction of the final version of the manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
5809631	29435681	HRK	2	supervised the work and were involved in the correction of the final version of the manuscript	supervised the work and were involved in the correction of the final version of the manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
5809631	29435681	JN	2	performed the nmr experiments as well as their interpretation	performed the nmr experiments as well as their interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5809631	29435681	JS	2	performed all the experimental work related with the in situ polymerization of phenolics|performed all the experimental work related with the in situ polymerization of phenolics|made the first draft of the manuscript	performed all the experimental work related with the in situ polymerization of phenolics	Performed the experiments	Investigation	YES
5809631	29435681	JS	2	performed all the experimental work related with the in situ polymerization of phenolics|performed all the experimental work related with the in situ polymerization of phenolics|made the first draft of the manuscript	performed all the experimental work related with the in situ polymerization of phenolics	Performed the experiments	Investigation	YES
5809631	29435681	JS	2	performed all the experimental work related with the in situ polymerization of phenolics|performed all the experimental work related with the in situ polymerization of phenolics|made the first draft of the manuscript	made the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
3491826	22684844	AGJ	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
3491826	22684844	BSMcK	PLoS52	contributed new reagents and analytical tools	contributed new reagents and analytical tools	Contributed reagents/materials/analysis tools	Resources	YES
3491826	22684844	BW	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
3491826	22684844	CDR	PLoS52	designed research|performed research	designed research	Conceived and designed the experiments	Methodology	YES
3491826	22684844	CDR	PLoS52	designed research|performed research	performed research	Performed the experiments	Investigation	YES
3491826	22684844	CMP	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
3491826	22684844	DAK	PLoS52	designed research	designed research	Conceived and designed the experiments	Methodology	YES
3491826	22684844	GJL	PLoS52	contributed new reagents and analytical tools	contributed new reagents and analytical tools	Contributed reagents/materials/analysis tools	Resources	YES
3491826	22684844	GPA	PLoS52	designed research	designed research	Conceived and designed the experiments	Methodology	YES
3491826	22684844	HJZ	PLoS52	designed research	designed research	Conceived and designed the experiments	Methodology	YES
3491826	22684844	HLL	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
3491826	22684844	JJ	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
3491826	22684844	ME	PLoS52	designed research|contributed new reagents and analytical tools|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
3491826	22684844	ME	PLoS52	designed research|contributed new reagents and analytical tools|wrote the paper	contributed new reagents and analytical tools	Contributed reagents/materials/analysis tools	Resources	YES
3491826	22684844	ME	PLoS52	designed research|contributed new reagents and analytical tools|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3491826	22684844	PS	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
3491826	22684844	RJJOD	PLoS52	designed research|performed research|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
3491826	22684844	RJJOD	PLoS52	designed research|performed research|wrote the paper	performed research	Performed the experiments	Investigation	YES
3491826	22684844	RJJOD	PLoS52	designed research|performed research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3491826	22684844	RJMcA	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
3491826	22684844	RV	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
3491826	22684844	SB	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
3491826	22684844	SEM	PLoS52	designed research|performed research|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
3491826	22684844	SEM	PLoS52	designed research|performed research|wrote the paper	performed research	Performed the experiments	Investigation	YES
3491826	22684844	SEM	PLoS52	designed research|performed research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3491826	22684844	SRJ	PLoS52	contributed new reagents and analytical tools	contributed new reagents and analytical tools	Contributed reagents/materials/analysis tools	Resources	YES
3491826	22684844	ST	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
4416933	25932941	AH	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416933	25932941	AP	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4416933	25932941	AP	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416933	25932941	IBO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416933	25932941	IBO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416933	25932941	IBO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416933	25932941	IBO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416933	25932941	JK	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416933	25932941	KCC	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416933	25932941	KCC	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416933	25932941	KP	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416933	25932941	KP	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416933	25932941	KP	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416933	25932941	M. Radkowski	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416933	25932941	M. Radkowski	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416933	25932941	M. Radkowski	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416933	25932941	M. Radkowski	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416933	25932941	M. Rosinska	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4416933	25932941	M. Rosinska	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416933	25932941	MF	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416933	25932941	MP	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416933	25932941	NK	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416933	25932941	NK	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416933	25932941	PZ	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4416933	25932941	PZ	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416933	25932941	RP	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4416933	25932941	RP	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416933	25932941	TL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416933	25932941	TL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416933	25932941	TL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5816930	29487609	CvL	2	designed the study, collected and analyzed the data, and wrote the manuscript	designed the study, collected and analyzed the data, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
6419943	30996991	A.P.	PLoS52	performed molecular simulations	performed molecular simulations	Performed the experiments	Formal analysis|Investigation	YES
6419943	30996991	C.I.	PLoS52	performed cross-linking studies	performed cross-linking studies	Performed the experiments	Investigation	YES
6419943	30996991	D.C.	PLoS52	performed spr experiments	performed spr experiments	Performed the experiments	Investigation	YES
6419943	30996991	D.M.	PLoS52	designed the research and wrote the paper	designed the research and wrote the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
6419943	30996991	D.S.	PLoS52	contributed to cell studies	contributed to cell studies	Performed the experiments	Investigation	YES
6419943	30996991	E.P.	PLoS52	performed mst experiments	performed mst experiments	Performed the experiments	Investigation	YES
6419943	30996991	F.B.	PLoS52	performed ide-mediated hydrolysis studies	performed ide-mediated hydrolysis studies	Performed the experiments	Investigation	YES
6419943	30996991	G.G.	PLoS52	analyzed spr data and designed the research	analyzed spr data and designed the research	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
6419943	30996991	G.R.T.	PLoS52	contributed to cell studies	contributed to cell studies	Performed the experiments	Investigation	YES
6419943	30996991	I.M.M.A.	PLoS52	performed maldi-tof studies	performed maldi-tof studies	Performed the experiments	Investigation	YES
6419943	30996991	L.P.	PLoS52	performed mst experiments	performed mst experiments	Performed the experiments	Investigation	YES
6419943	30996991	M.C.	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6419943	30996991	R.F.	PLoS52	performed nmr studies	performed nmr studies	Performed the experiments	Investigation	YES
6419943	30996991	S.G.V.	PLoS52	performed polyubiquitination reactions	performed polyubiquitination reactions	Performed the experiments	Investigation	YES
6419943	30996991	V.G.N.	PLoS52	performed elisa assays	performed elisa assays	Performed the experiments	Investigation	YES
6419943	30996991	V.L.	PLoS52	performed polyubiquitination reactions	performed polyubiquitination reactions	Performed the experiments	Investigation	YES
1978527	17895988	AW	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1978527	17895988	CM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1978527	17895988	DB	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1978527	17895988	DW	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1978527	17895988	JB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1978527	17895988	JB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1978527	17895988	JH	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1978527	17895988	JH	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1978527	17895988	JN	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1978527	17895988	JP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1978527	17895988	JP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1978527	17895988	JP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1978527	17895988	JW	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1978527	17895988	JW	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1978527	17895988	KK	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1978527	17895988	NB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1978527	17895988	PG	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1978527	17895988	PK	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1978527	17895988	PK	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1978527	17895988	RA	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1978527	17895988	RA	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1978527	17895988	RA	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1978527	17895988	RS	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1978527	17895988	SB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1978527	17895988	SB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1978527	17895988	SB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1978527	17895988	SG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1978527	17895988	SG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1978527	17895988	SG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1978527	17895988	TB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1978527	17895988	XW	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1978527	17895988	YZ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1978527	17895988	ZD	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1978527	17895988	ZD	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1978527	17895988	ZD	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5773898	29219081	All authors	2	participated in the analysis of the data, interpretation of the results, and review of the paper	participated in the analysis of the data, interpretation of the results, and review of the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5773898	29219081	DL	2	performed the mathematical analysis|drafted the paper	performed the mathematical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5773898	29219081	DL	2	performed the mathematical analysis|drafted the paper	drafted the paper	Wrote the paper	Writing - Original Draft	YES
5773898	29219081	EL	2	reviewed the mathematical analysis|revised the paper	reviewed the mathematical analysis	Analyzed the data	Formal analysis	YES
5773898	29219081	EL	2	reviewed the mathematical analysis|revised the paper	revised the paper	Wrote the paper	Writing - Review & Editing	YES
5773898	29219081	HW	2	designed the algorithm	designed the algorithm	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
5773898	29219081	HZ	2	performed the mathematical analysis|designed the algorithm|implemented the algorithm|generated the data|drafted the paper	performed the mathematical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5773898	29219081	HZ	2	performed the mathematical analysis|designed the algorithm|implemented the algorithm|generated the data|drafted the paper	designed the algorithm	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
5773898	29219081	HZ	2	performed the mathematical analysis|designed the algorithm|implemented the algorithm|generated the data|drafted the paper	implemented the algorithm	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5773898	29219081	HZ	2	performed the mathematical analysis|designed the algorithm|implemented the algorithm|generated the data|drafted the paper	generated the data	Performed the experiments	Investigation	YES
5773898	29219081	HZ	2	performed the mathematical analysis|designed the algorithm|implemented the algorithm|generated the data|drafted the paper	drafted the paper	Wrote the paper	Writing - Original Draft	YES
5773898	29219081	JM	2	reviewed the mathematical analysis|revised the paper	reviewed the mathematical analysis	Analyzed the data	Formal analysis	YES
5773898	29219081	JM	2	reviewed the mathematical analysis|revised the paper	revised the paper	Wrote the paper	Writing - Review & Editing	YES
5773898	29219081	MZ	2	performed the mathematical analysis|drafted the paper	performed the mathematical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5773898	29219081	MZ	2	performed the mathematical analysis|drafted the paper	drafted the paper	Wrote the paper	Writing - Original Draft	YES
5773898	29219081	XZ	2	generated the data	generated the data	Performed the experiments	Investigation	YES
3428968	22688300	EF	2	contributed equally to the manuscript	contributed equally to the manuscript	-	-	NO
3428968	22688300	SB	2	contributed equally to the manuscript	contributed equally to the manuscript	-	-	NO
6270774	25353383	H.N.	2	performed the research and analyzed the data	performed the research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270774	25353383	M.Z.	2	conceived and designed the research|performed the research and analyzed the data|wrote the manuscript	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
6270774	25353383	M.Z.	2	conceived and designed the research|performed the research and analyzed the data|wrote the manuscript	performed the research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270774	25353383	M.Z.	2	conceived and designed the research|performed the research and analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6270774	25353383	X.J.	2	performed the research and analyzed the data	performed the research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270774	25353383	Y.W.	2	performed the research and analyzed the data	performed the research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270774	25353383	Z.L.	2	conceived and designed the research|wrote the manuscript	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
6270774	25353383	Z.L.	2	conceived and designed the research|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
1978528	17895977	EK	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1978528	17895977	EK	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1978528	17895977	ZZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1978528	17895977	ZZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1978528	17895977	ZZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1978528	17895977	ZZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1978528	17895977	ZZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3491827	22707389	J.A.R-H	PLoS52	performed analysis	performed analysis	Performed the experiments	Investigation	YES
3491827	22707389	J.Y.	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
3491827	22707389	K.H.	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
3491827	22707389	N.R.	PLoS52	performed research|wrote the paper	performed research	Performed the experiments	Investigation	YES
3491827	22707389	N.R.	PLoS52	performed research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3491827	22707389	N.Y.R.A.	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
3491827	22707389	P-W.C.	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
3491827	22707389	R.S.B.	PLoS52	performed analysis|wrote the paper	performed analysis	Performed the experiments	Investigation	YES
3491827	22707389	R.S.B.	PLoS52	performed analysis|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3491827	22707389	S-K.N.	PLoS52	performed analysis	performed analysis	Performed the experiments	Investigation	YES
3491827	22707389	S-W.N.	PLoS52	designed research|performed analysis|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
3491827	22707389	S-W.N.	PLoS52	designed research|performed analysis|wrote the paper	performed analysis	Performed the experiments	Investigation	YES
3491827	22707389	S-W.N.	PLoS52	designed research|performed analysis|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3491827	22707389	S.L.	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
3491827	22707389	W-P.F.	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
3491827	22707389	W.R.W.	PLoS52	performed analysis	performed analysis	Performed the experiments	Investigation	YES
3491827	22707389	Y.Z.	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
4416934	25933216	AJB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416934	25933216	AJJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416934	25933216	AJJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416934	25933216	AJJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416934	25933216	AJL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416934	25933216	BLC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416934	25933216	DNR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416934	25933216	DNR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416934	25933216	DNR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416934	25933216	DNR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416934	25933216	FJ	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4416934	25933216	FJ	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4416934	25933216	IFP	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416934	25933216	IP	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416934	25933216	JDG	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416934	25933216	JNS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416934	25933216	JRO	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416934	25933216	KDP	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416934	25933216	LMH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416934	25933216	MC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5095533	28080980	A.A.C.	PLoS52	collected the data	collected the data	Performed the experiments	Investigation	YES
5095533	28080980	A.L.	PLoS52	collected the data	collected the data	Performed the experiments	Investigation	YES
5095533	28080980	D.S.S.	PLoS52	collected the data	collected the data	Performed the experiments	Investigation	YES
5095533	28080980	F.C.	PLoS52	collected the data|analysed the data|wrote the paper	collected the data	Performed the experiments	Investigation	YES
5095533	28080980	F.C.	PLoS52	collected the data|analysed the data|wrote the paper	analysed the data	Analyzed the data	Formal analysis	YES
5095533	28080980	F.C.	PLoS52	collected the data|analysed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5095533	28080980	J.B.	PLoS52	collected the data|collected the data|collected the data|analysed the data|analysed the data	collected the data	Performed the experiments	Investigation	YES
5095533	28080980	J.B.	PLoS52	collected the data|collected the data|collected the data|analysed the data|analysed the data	collected the data	Performed the experiments	Investigation	YES
5095533	28080980	J.B.	PLoS52	collected the data|collected the data|collected the data|analysed the data|analysed the data	collected the data	Performed the experiments	Investigation	YES
5095533	28080980	J.B.	PLoS52	collected the data|collected the data|collected the data|analysed the data|analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
5095533	28080980	J.B.	PLoS52	collected the data|collected the data|collected the data|analysed the data|analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
5095533	28080980	M.A.S.	PLoS52	analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
5095533	28080980	M.C.F.	PLoS52	collected the data|wrote the paper	collected the data	Performed the experiments	Investigation	YES
5095533	28080980	M.C.F.	PLoS52	collected the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5095533	28080980	M.R.	PLoS52	analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
5095533	28080980	O.D.	PLoS52	collected the data	collected the data	Performed the experiments	Investigation	YES
5095533	28080980	T.J.	PLoS52	analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
5095533	28080980	T.W.J.G.	PLoS52	collected the data	collected the data	Performed the experiments	Investigation	YES
5810308	29429071	All	2	data will be posted online in the advent of acceptance of the manuscript for publication by the journal	data will be posted online in the advent of acceptance of the manuscript for publication by the journal	-	-	NO
5810308	29429071	All authors	2	read and approved the final manuscript|have seen and consented to submission of this manuscript in its current form	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5810308	29429071	All authors	2	read and approved the final manuscript|have seen and consented to submission of this manuscript in its current form	have seen and consented to submission of this manuscript in its current form	-	-	NO
5810308	29429071	DD	2	performed data analysis	performed data analysis	Analyzed the data	Formal analysis	YES
5810308	29429071	EH	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5810308	29429071	JZ	2	raised the fish and operated the recirculating aquaculture system	raised the fish and operated the recirculating aquaculture system	Performed the experiments	Investigation	YES
5810308	29429071	LP	2	performed data analysis	performed data analysis	Analyzed the data	Formal analysis	YES
5810308	29429071	TM	2	conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5810308	29429071	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5810308	29429071	WL	2	raised the fish and operated the recirculating aquaculture system	raised the fish and operated the recirculating aquaculture system	Performed the experiments	Investigation	YES
5810308	29429071	XS	2	prepared materials for submission for dna sequencing	prepared materials for submission for dna sequencing	Performed the experiments	Investigation	YES
5810308	29429071	YL	2	conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5810308	29429071	ZH	2	conceived the study|prepared materials for submission for dna sequencing|wrote the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5810308	29429071	ZH	2	conceived the study|prepared materials for submission for dna sequencing|wrote the manuscript	prepared materials for submission for dna sequencing	Performed the experiments	Investigation	YES
5810308	29429071	ZH	2	conceived the study|prepared materials for submission for dna sequencing|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5774091	29347912	CHY	PLoS52	contributed to data collection	contributed to data collection	Performed the experiments	Investigation	YES
5774091	29347912	CZ	PLoS52	contributed to data collection	contributed to data collection	Performed the experiments	Investigation	YES
5774091	29347912	DDW	PLoS52	collected the public dataset, perform bioinformatics analysis and also drafted the manuscript	collected the public dataset, perform bioinformatics analysis and also drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5774091	29347912	HLM	PLoS52	conceived this study and reviewed the manuscript	conceived this study and reviewed the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5774091	29347912	NNK	PLoS52	contributed to data collection|performed the experiments	contributed to data collection	Performed the experiments	Investigation	YES
5774091	29347912	NNK	PLoS52	contributed to data collection|performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5774091	29347912	PZ	PLoS52	collected the public dataset, perform bioinformatics analysis and also drafted the manuscript|performed the experiments	collected the public dataset, perform bioinformatics analysis and also drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5774091	29347912	PZ	PLoS52	collected the public dataset, perform bioinformatics analysis and also drafted the manuscript|performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5774091	29347912	QC	PLoS52	conceived this study and reviewed the manuscript	conceived this study and reviewed the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5774091	29347912	RQW	PLoS52	contributed to bioinformatics analysis and the making of all the figures and tables	contributed to bioinformatics analysis and the making of all the figures and tables	-	Formal analysis|Visualization	YES
5774091	29347912	WTW	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5817061	29491873	All authors	2	contributed to the redaction of the article	contributed to the redaction of the article	-	-	NO
5817061	29491873	JV	2	proposed and developed the concepts	proposed and developed the concepts	Conceived and designed the experiments	Conceptualization	YES
6270775	25299819	Chang Hwa Jung	2	conducted the research and analyzed the data	conducted the research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270775	25299819	Jiyun Ahn	2	conducted the research and analyzed the data	conducted the research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270775	25299819	Min Young Um	2	conducted the research and analyzed the data	conducted the research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270775	25299819	Myung Kyu Park	2	conducted the research and analyzed the data	conducted the research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270775	25299819	Tae Youl Ha	2	designed the research and performed substantial editing as a corresponding author	designed the research and performed substantial editing as a corresponding author	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
6270775	25299819	Won Hee Choi	2	performed the experimental work, acquired and analyzed the data and wrote the original manuscript as a first author	performed the experimental work, acquired and analyzed the data and wrote the original manuscript as a first author	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5095537	28080984	A.D.	2	collected the preliminary data	collected the preliminary data	Performed the experiments	Investigation	YES
5095537	28080984	D.B.	2	conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5095537	28080984	S.G.	2	conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
4416935	25932649	CW	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416935	25932649	EG	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416935	25932649	GJ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416935	25932649	GJ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416935	25932649	GJ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416935	25932649	HZ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416935	25932649	JL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416935	25932649	JS	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416935	25932649	Shujun Wang Suying	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416935	25932649	XD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416935	25932649	XD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416935	25932649	XD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416935	25932649	XD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416935	25932649	XL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416935	25932649	YL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4416935	25932649	ZN	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1978529	17895998	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1978529	17895998	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1978529	17895998	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1978529	17895998	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1978529	17895998	CA	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1978529	17895998	CA	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1978529	17895998	CL	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1978529	17895998	CL	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
3491828	22821859	CEC	CRediT	Study concept and design	Study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
3491828	22821859	JLI	CRediT	Study concept and design|supervision	Study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
3491828	22821859	JLI	CRediT	Study concept and design|supervision	supervision	-	Supervision	YES
3491828	22821859	RU	CRediT	Study concept and design	Study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5817064	29491879	FC	2	carried out blup analysis and produced the graphs	carried out blup analysis and produced the graphs	Performed the experiments	Investigation	YES
5817064	29491879	GM	2	carried out the phylogenetic analysis for the snp markers and created the nj tree	carried out the phylogenetic analysis for the snp markers and created the nj tree	Performed the experiments	Investigation	YES
5817064	29491879	JM	2	provided the snp markers data, assisted with the snp data analysis and edited the manuscript	provided the snp markers data, assisted with the snp data analysis and edited the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
5817064	29491879	LF	2	carried out the experimental work, which included experimental design, phenotyping data collection, snp data analysis and candidate genes identification, produced qtl graphs and wrote the manuscript	carried out the experimental work, which included experimental design, phenotyping data collection, snp data analysis and candidate genes identification, produced qtl graphs and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5817064	29491879	SR	2	performed the qtl mapping analysis, assisted with snp data analysis, and helped editing the manuscript	performed the qtl mapping analysis, assisted with snp data analysis, and helped editing the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
3428970	22688302	IS	2	data descriptions suggestion and study assistance	data descriptions suggestion and study assistance	-	-	NO
3428970	22688302	KI	2	experiment design and conduction, data analysis, manuscript drafting	experiment design and conduction, data analysis, manuscript drafting	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
3428970	22688302	MK	2	initial project, experiment conduction, data analysis, manuscript drafting	initial project, experiment conduction, data analysis, manuscript drafting	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5774113	29347914	All authors	2	contributed to data interpretation, manuscript development	contributed to data interpretation, manuscript development	Analyzed the data	Formal analysis	YES
5774113	29347914	JMF	2	executed all experiments, analyzed data, performed bioinformatics analyses, and wrote the manuscript	executed all experiments, analyzed data, performed bioinformatics analyses, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5774113	29347914	SFL	2	assisted in the execution of experiments and data analyses	assisted in the execution of experiments and data analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5811423	29442257	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5811423	29442257	BZ	2	interpreted data	interpreted data	Analyzed the data	Formal analysis	YES
5811423	29442257	DG	2	interpreted data	interpreted data	Analyzed the data	Formal analysis	YES
5811423	29442257	DW	2	conducted the experiments and analyzed the results	conducted the experiments and analyzed the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5811423	29442257	JL	2	conceived the experiments	conceived the experiments	Conceived and designed the experiments	Conceptualization	YES
5811423	29442257	JZ	2	conducted the experiments and analyzed the results	conducted the experiments and analyzed the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5811423	29442257	MM	2	conducted the experiments and analyzed the results|interpreted data|wrote the manuscript	conducted the experiments and analyzed the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5811423	29442257	MM	2	conducted the experiments and analyzed the results|interpreted data|wrote the manuscript	interpreted data	Analyzed the data	Formal analysis	YES
5811423	29442257	MM	2	conducted the experiments and analyzed the results|interpreted data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5811423	29442257	MO	2	conceived the experiments|edited the manuscript	conceived the experiments	Conceived and designed the experiments	Conceptualization	YES
5811423	29442257	MO	2	conceived the experiments|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5811423	29442257	WL	2	edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5811423	29442257	XJ	2	conceived the experiments	conceived the experiments	Conceived and designed the experiments	Conceptualization	YES
1978530	17896000	CC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1978530	17896000	CC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1978530	17896000	CC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1978530	17896000	DE	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1978530	17896000	DM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1978530	17896000	MP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1978530	17896000	MP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1978530	17896000	MP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1978530	17896000	MP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1978530	17896000	TL	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5095540	28080987	J.B.	2	conceived and drafted the article, revised it critically and approved the final version	conceived and drafted the article, revised it critically and approved the final version	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
5095540	28080987	N.B.W.	2	contributed to drafting the article and provided input for critical revision and approved the final version	contributed to drafting the article and provided input for critical revision and approved the final version	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5095540	28080987	N.S.	2	contributed to and provided input for critical revision and approved the final version	contributed to and provided input for critical revision and approved the final version	Wrote the paper	Writing - Review & Editing	YES
6270776	25232708	JV	2	was deeply involved in the manuscript correction and revision	was deeply involved in the manuscript correction and revision	Wrote the paper	Writing - Review & Editing	YES
4416936	25933288	AC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416936	25933288	AC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416936	25933288	AC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416936	25933288	AC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416936	25933288	AE	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416936	25933288	AE	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416936	25933288	AE	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416936	25933288	SNS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416936	25933288	SNS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416936	25933288	SNS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416936	25933288	SNS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416936	25933288	SS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4416936	25933288	SS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4416936	25933288	SS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416936	25933288	VP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416936	25933288	VP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416936	25933288	VP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416936	25933288	VP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3491829	22903875	AE	2	undertook the in vitro studies	undertook the in vitro studies	Performed the experiments	Investigation	YES
3491829	22903875	AMJ	2	undertook the in vivo visual function analyses	undertook the in vivo visual function analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
3491829	22903875	BdS	2	provided the knockout animals and tissue samples|wrote the manuscript with input from the other authors	provided the knockout animals and tissue samples	Contributed reagents/materials/analysis tools	Resources	YES
3491829	22903875	BdS	2	provided the knockout animals and tissue samples|wrote the manuscript with input from the other authors	wrote the manuscript with input from the other authors	Wrote the paper	Writing - Original Draft	YES
3491829	22903875	CBR	2	assisted in data analysis	assisted in data analysis	Analyzed the data	Formal analysis	YES
3491829	22903875	JC	2	designed the study|undertook the in vitro studies|wrote the manuscript with input from the other authors	designed the study	Conceived and designed the experiments	Methodology	YES
3491829	22903875	JC	2	designed the study|undertook the in vitro studies|wrote the manuscript with input from the other authors	undertook the in vitro studies	Performed the experiments	Investigation	YES
3491829	22903875	JC	2	designed the study|undertook the in vitro studies|wrote the manuscript with input from the other authors	wrote the manuscript with input from the other authors	Wrote the paper	Writing - Original Draft	YES
3491829	22903875	LL	2	undertook the in vitro studies	undertook the in vitro studies	Performed the experiments	Investigation	YES
3491829	22903875	LS	2	provided the knockout animals and tissue samples	provided the knockout animals and tissue samples	Contributed reagents/materials/analysis tools	Resources	YES
3491829	22903875	MBG	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
3491829	22903875	MEB	2	designed the study|wrote the manuscript with input from the other authors	designed the study	Conceived and designed the experiments	Methodology	YES
3491829	22903875	MEB	2	designed the study|wrote the manuscript with input from the other authors	wrote the manuscript with input from the other authors	Wrote the paper	Writing - Original Draft	YES
3491829	22903875	NK	2	undertook the in vivo visual function analyses	undertook the in vivo visual function analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
3491829	22903875	PS	2	provided the knockout animals and tissue samples	provided the knockout animals and tissue samples	Contributed reagents/materials/analysis tools	Resources	YES
3491829	22903875	QR	2	undertook the in vitro studies	undertook the in vitro studies	Performed the experiments	Investigation	YES
3491829	22903875	SH	2	performed the histological analysis and immunohistochemistry	performed the histological analysis and immunohistochemistry	Performed the experiments	Investigation	YES
3491829	22903875	SS	2	undertook the in vivo visual function analyses	undertook the in vivo visual function analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
3491829	22903875	TG	2	assisted in data analysis	assisted in data analysis	Analyzed the data	Formal analysis	YES
3491829	22903875	XQ	2	performed the histological analysis and immunohistochemistry	performed the histological analysis and immunohistochemistry	Performed the experiments	Investigation	YES
3491829	22903875	ZC	2	performed the histological analysis and immunohistochemistry	performed the histological analysis and immunohistochemistry	Performed the experiments	Investigation	YES
3888757	24453901	All authors	2	critically reviewed the paper and approved the final version submitted for publication	critically reviewed the paper and approved the final version submitted for publication	Wrote the paper	Writing - Review & Editing	YES
3888757	24453901	Rajesh Jeewon	2	carried out the study design|prepared the paper	carried out the study design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3888757	24453901	Rajesh Jeewon	2	carried out the study design|prepared the paper	prepared the paper	Wrote the paper	Writing - Original Draft	YES
3888757	24453901	Trishnee Bhurosy	2	carried out the study design|did the data collection|carried out statistical analysis|prepared the paper	carried out the study design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3888757	24453901	Trishnee Bhurosy	2	carried out the study design|did the data collection|carried out statistical analysis|prepared the paper	did the data collection	Performed the experiments	Investigation	YES
3888757	24453901	Trishnee Bhurosy	2	carried out the study design|did the data collection|carried out statistical analysis|prepared the paper	carried out statistical analysis	Analyzed the data	Formal analysis	YES
3888757	24453901	Trishnee Bhurosy	2	carried out the study design|did the data collection|carried out statistical analysis|prepared the paper	prepared the paper	Wrote the paper	Writing - Original Draft	YES
5817070	29491869	DQ	PLoS52	conducted the experiments	conducted the experiments	Performed the experiments	Investigation	YES
5817070	29491869	HZ	PLoS52	performed the phenotypic tests and other works involved in this study	performed the phenotypic tests and other works involved in this study	Performed the experiments	Investigation	YES
5817070	29491869	HjL	PLoS52	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5817070	29491869	HwL	PLoS52	performed the phenotypic tests and other works involved in this study	performed the phenotypic tests and other works involved in this study	Performed the experiments	Investigation	YES
5817070	29491869	JH	PLoS52	conducted the experiments	conducted the experiments	Performed the experiments	Investigation	YES
5817070	29491869	JL	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5817070	29491869	JX	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5817070	29491869	LY	PLoS52	performed the phenotypic tests and other works involved in this study	performed the phenotypic tests and other works involved in this study	Performed the experiments	Investigation	YES
5817070	29491869	ML	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5817070	29491869	PW	PLoS52	conceived and designed the study|conducted the experiments|analyzed the data	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5817070	29491869	PW	PLoS52	conceived and designed the study|conducted the experiments|analyzed the data	conducted the experiments	Performed the experiments	Investigation	YES
5817070	29491869	PW	PLoS52	conceived and designed the study|conducted the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5817070	29491869	ZL	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5774138	29347911	AM	PLoS52	analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
5774138	29347911	All authors	PLoS52	revised and approved the final manuscript	revised and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5774138	29347911	DG	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5774138	29347911	GNW	PLoS52	conceived and designed the study|analysed the data	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5774138	29347911	GNW	PLoS52	conceived and designed the study|analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
5774138	29347911	JH	PLoS52	analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
5774138	29347911	NJW	PLoS52	performed the experiments|analysed the data|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5774138	29347911	NJW	PLoS52	performed the experiments|analysed the data|wrote the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
5774138	29347911	NJW	PLoS52	performed the experiments|analysed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5774138	29347911	SM	PLoS52	analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
5774138	29347911	TD	PLoS52	analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
1978531	17896001	BS	PLoS5	Conceived and designed the experiments|Analyzed the data|Transgenic constructs design|Transgenic mice production|Results discussion	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1978531	17896001	BS	PLoS5	Conceived and designed the experiments|Analyzed the data|Transgenic constructs design|Transgenic mice production|Results discussion	Analyzed the data	Analyzed the data	Formal analysis	YES
1978531	17896001	BS	PLoS5	Conceived and designed the experiments|Analyzed the data|Transgenic constructs design|Transgenic mice production|Results discussion	Transgenic constructs design	Conceived and designed the experiments|Performed the experiments	Investigation	YES
1978531	17896001	BS	PLoS5	Conceived and designed the experiments|Analyzed the data|Transgenic constructs design|Transgenic mice production|Results discussion	Transgenic mice production	Performed the experiments	Investigation	YES
1978531	17896001	BS	PLoS5	Conceived and designed the experiments|Analyzed the data|Transgenic constructs design|Transgenic mice production|Results discussion	Results discussion	-	-	NO
1978531	17896001	CR	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1978531	17896001	CR	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1978531	17896001	JB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1978531	17896001	JB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1978531	17896001	JB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1978531	17896001	MK	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1978531	17896001	MK	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1978531	17896001	SH	PLoS5	Performed the experiments|Transgenic mice production	Performed the experiments	Performed the experiments	Investigation	YES
1978531	17896001	SH	PLoS5	Performed the experiments|Transgenic mice production	Transgenic mice production	Performed the experiments	Investigation	YES
1978531	17896001	TK	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1978531	17896001	TK	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
3491830	22767436	AR	2	performed research	performed research	Performed the experiments	Investigation	YES
3491830	22767436	CN	2	designed research and were responsible for intellectual content|performed research|analyzed data|wrote the article	designed research and were responsible for intellectual content	Conceived and designed the experiments	Methodology	YES
3491830	22767436	CN	2	designed research and were responsible for intellectual content|performed research|analyzed data|wrote the article	performed research	Performed the experiments	Investigation	YES
3491830	22767436	CN	2	designed research and were responsible for intellectual content|performed research|analyzed data|wrote the article	analyzed data	Analyzed the data	Formal analysis	YES
3491830	22767436	CN	2	designed research and were responsible for intellectual content|performed research|analyzed data|wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
3491830	22767436	EP	2	performed research	performed research	Performed the experiments	Investigation	YES
3491830	22767436	HJS	2	performed research|analyzed data	performed research	Performed the experiments	Investigation	YES
3491830	22767436	HJS	2	performed research|analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
3491830	22767436	LCZ	2	designed research and were responsible for intellectual content|performed research|analyzed data|wrote the article	designed research and were responsible for intellectual content	Conceived and designed the experiments	Methodology	YES
3491830	22767436	LCZ	2	designed research and were responsible for intellectual content|performed research|analyzed data|wrote the article	performed research	Performed the experiments	Investigation	YES
3491830	22767436	LCZ	2	designed research and were responsible for intellectual content|performed research|analyzed data|wrote the article	analyzed data	Analyzed the data	Formal analysis	YES
3491830	22767436	LCZ	2	designed research and were responsible for intellectual content|performed research|analyzed data|wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
3491830	22767436	MPZ	2	performed research|analyzed data	performed research	Performed the experiments	Investigation	YES
3491830	22767436	MPZ	2	performed research|analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
3491830	22767436	MWB	2	designed research and were responsible for intellectual content|analyzed data	designed research and were responsible for intellectual content	Conceived and designed the experiments	Methodology	YES
3491830	22767436	MWB	2	designed research and were responsible for intellectual content|analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5812119	29429128	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5812119	29429128	MHA	2	designed and performed the experiments|helped draft the manuscript	designed and performed the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5812119	29429128	MHA	2	designed and performed the experiments|helped draft the manuscript	helped draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5812119	29429128	MM	2	helped design the experiments|helped draft the manuscript	helped design the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5812119	29429128	MM	2	helped design the experiments|helped draft the manuscript	helped draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5812119	29429128	SB	2	conceived the study|helped design the experiments|helped draft the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5812119	29429128	SB	2	conceived the study|helped design the experiments|helped draft the manuscript	helped design the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5812119	29429128	SB	2	conceived the study|helped design the experiments|helped draft the manuscript	helped draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5812119	29429128	SK	2	conceived the study|helped design the experiments	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5812119	29429128	SK	2	conceived the study|helped design the experiments	helped design the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5812119	29429128	TS	2	designed and performed the experiments|helped draft the manuscript	designed and performed the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5812119	29429128	TS	2	designed and performed the experiments|helped draft the manuscript	helped draft the manuscript	Wrote the paper	Writing - Original Draft	YES
4416937	25933101	AY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416937	25933101	AY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4416937	25933101	AY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4416937	25933101	AY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4416937	25933101	AY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4416937	25933101	TO	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4416937	25933101	TO	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
3428972	22688304	HF	2	experiments performance, data collect	experiments performance, data collect	Performed the experiments	Investigation	YES
3428972	22688304	RS	2	data discussion, manuscript revision	data discussion, manuscript revision	Wrote the paper	Writing - Review & Editing	YES
3428972	22688304	SS	2	experimental system design, experiments performance, data collect, manuscript drafting	experimental system design, experiments performance, data collect, manuscript drafting	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
3428972	22688304	TA	2	experiments performance, data collect	experiments performance, data collect	Performed the experiments	Investigation	YES
3428972	22688304	YS	2	contribution to establishment of experimental systems and results discussion	contribution to establishment of experimental systems and results discussion	Performed the experiments	Investigation	YES
4637443	26587538	H. W. Schulze	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
1978532	17895991	BB	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1978532	17895991	BB	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1978532	17895991	GG	PLoS5	Contributed reagents/materials/analysis tools|Performed some sequencing|Performed the experiments for determination of co-receptor usage	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1978532	17895991	GG	PLoS5	Contributed reagents/materials/analysis tools|Performed some sequencing|Performed the experiments for determination of co-receptor usage	Performed some sequencing	Performed the experiments	Investigation	YES
1978532	17895991	GG	PLoS5	Contributed reagents/materials/analysis tools|Performed some sequencing|Performed the experiments for determination of co-receptor usage	Performed the experiments for determination of co-receptor usage	Performed the experiments	Investigation	YES
1978532	17895991	JS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1978532	17895991	MG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1978532	17895991	MG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1978532	17895991	MG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1978532	17895991	MS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1978532	17895991	MS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1978532	17895991	MS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1978532	17895991	MS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1978532	17895991	RG	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418564	25938537	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418564	25938537	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418564	25938537	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418564	25938537	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418564	25938537	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418564	25938537	PMM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418564	25938537	PMM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418564	25938537	PMM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418564	25938537	PMM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418564	25938537	PMM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3428973	22688305	FACB	2	treatment of rats and tissue preparation|histochemistry performing	treatment of rats and tissue preparation	-	-	NO
3428973	22688305	FACB	2	treatment of rats and tissue preparation|histochemistry performing	histochemistry performing	Performed the experiments	Investigation	YES
3428973	22688305	LBF	2	treatment of rats and tissue preparation	treatment of rats and tissue preparation	-	-	NO
3428973	22688305	LFM	2	study conception and design|treatment of rats and tissue preparation	study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
3428973	22688305	LFM	2	study conception and design|treatment of rats and tissue preparation	treatment of rats and tissue preparation	-	-	NO
3428973	22688305	TRAP	2	histochemistry performing	histochemistry performing	Performed the experiments	Investigation	YES
3428973	22688305	VBC	2	study conception and design|treatment of rats and tissue preparation|ultrastructural immunocytochemistry performing|article drafting and final manuscript writing	study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
3428973	22688305	VBC	2	study conception and design|treatment of rats and tissue preparation|ultrastructural immunocytochemistry performing|article drafting and final manuscript writing	treatment of rats and tissue preparation	-	-	NO
3428973	22688305	VBC	2	study conception and design|treatment of rats and tissue preparation|ultrastructural immunocytochemistry performing|article drafting and final manuscript writing	ultrastructural immunocytochemistry performing	Performed the experiments	Investigation	YES
3428973	22688305	VBC	2	study conception and design|treatment of rats and tissue preparation|ultrastructural immunocytochemistry performing|article drafting and final manuscript writing	article drafting and final manuscript writing	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3428973	22688305	VEAC	2	study conception and design|article drafting and final manuscript writing	study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
3428973	22688305	VEAC	2	study conception and design|article drafting and final manuscript writing	article drafting and final manuscript writing	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3491831	22903887	AA	2	shared expertise and provided the aav vectors and viruses	shared expertise and provided the aav vectors and viruses	Contributed reagents/materials/analysis tools	Resources	YES
3491831	22903887	AB	2	performed tandem mass measurements in plasma	performed tandem mass measurements in plasma	Performed the experiments	Investigation	YES
3491831	22903887	CL	2	performed histochemical analysis	performed histochemical analysis	Performed the experiments	Investigation	YES
3491831	22903887	CV	2	designed the experimental plan and wrote the manuscript	designed the experimental plan and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3491831	22903887	IDM	2	performed the in vivo experiments	performed the in vivo experiments	Performed the experiments	Investigation	YES
3491831	22903887	MZ	2	designed the experimental plan and wrote the manuscript	designed the experimental plan and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
6270778	25004073	D.H.-L.	2	are equally contributed in the writing, design, synthesis, biological evaluation and analysis of the data	are equally contributed in the writing, design, synthesis, biological evaluation and analysis of the data	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources	YES
6270778	25004073	E.P.	2	are equally contributed in the writing, design, synthesis, biological evaluation and analysis of the data	are equally contributed in the writing, design, synthesis, biological evaluation and analysis of the data	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources	YES
6270778	25004073	G.G.	2	in the cytotoxicity assays	in the cytotoxicity assays	Performed the experiments	Investigation	YES
5817087	29491881	MB	2	took part in the experimental design, the interpretation of data and writing up	took part in the experimental design, the interpretation of data and writing up	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology	YES
5817087	29491881	MP	2	took part in the experimental design, acquisition, analysis, and interpretation of data, and on writing up	took part in the experimental design, acquisition, analysis, and interpretation of data, and on writing up	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology	YES
5817087	29491881	MP-B	2	took part in the experimental design, acquisition, analysis, and interpretation of data, and on writing up	took part in the experimental design, acquisition, analysis, and interpretation of data, and on writing up	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology	YES
5815975	29453676	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5815975	29453676	LY	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5815975	29453676	LY	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5815975	29453676	LYJ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5815975	29453676	QYS	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5815975	29453676	QYS	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5815975	29453676	RAD	PLoS52	revised the paper	revised the paper	Wrote the paper	Writing - Review & Editing	YES
5815975	29453676	TW	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5815975	29453676	XLC	PLoS52	designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5815975	29453676	XLC	PLoS52	designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5815975	29453676	XLC	PLoS52	designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5815975	29453676	XLC	PLoS52	designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4637448	26587545	All authors	2	contributed to the writing of the paper|have confirmed and approved the final version of this paper	contributed to the writing of the paper	Wrote the paper	Writing - Original Draft	YES
4637448	26587545	All authors	2	contributed to the writing of the paper|have confirmed and approved the final version of this paper	have confirmed and approved the final version of this paper	-	-	NO
4637448	26587545	Gunnar Seemanns	2	laboratory, for the simulations	laboratory, for the simulations	-	Formal analysis	YES
4637448	26587545	Irina V. Biktasheva	2	conceptualised and designed the simulations|analysed and interpreted the simulation results	conceptualised and designed the simulations	Conceived and designed the experiments	Conceptualization|Formal analysis	YES
4637448	26587545	Irina V. Biktasheva	2	conceptualised and designed the simulations|analysed and interpreted the simulation results	analysed and interpreted the simulation results	Analyzed the data	Formal analysis	YES
4637448	26587545	Sanjay R. Kharche	2	conceptualised and designed the simulations|conducted the simulations and visualization|analysed and interpreted the simulation results	conceptualised and designed the simulations	Conceived and designed the experiments	Conceptualization|Formal analysis	YES
4637448	26587545	Sanjay R. Kharche	2	conceptualised and designed the simulations|conducted the simulations and visualization|analysed and interpreted the simulation results	conducted the simulations and visualization	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
4637448	26587545	Sanjay R. Kharche	2	conceptualised and designed the simulations|conducted the simulations and visualization|analysed and interpreted the simulation results	analysed and interpreted the simulation results	Analyzed the data	Formal analysis	YES
4637448	26587545	Vadim N. Biktashev	2	conceptualised and designed the simulations|analysed and interpreted the simulation results	conceptualised and designed the simulations	Conceived and designed the experiments	Conceptualization|Formal analysis	YES
4637448	26587545	Vadim N. Biktashev	2	conceptualised and designed the simulations|analysed and interpreted the simulation results	analysed and interpreted the simulation results	Analyzed the data	Formal analysis	YES
5774168	29347977	AM	2	conceived the research work|contributed reagents and materials|wrote the manuscript|read, and approved the final manuscript	conceived the research work	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5774168	29347977	AM	2	conceived the research work|contributed reagents and materials|wrote the manuscript|read, and approved the final manuscript	contributed reagents and materials	Contributed reagents/materials/analysis tools	Resources	YES
5774168	29347977	AM	2	conceived the research work|contributed reagents and materials|wrote the manuscript|read, and approved the final manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5774168	29347977	AM	2	conceived the research work|contributed reagents and materials|wrote the manuscript|read, and approved the final manuscript	read, and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5774168	29347977	RB	2	conceived the research work|designed, performed experiments and analyzed the data|wrote the manuscript|read, and approved the final manuscript	conceived the research work	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5774168	29347977	RB	2	conceived the research work|designed, performed experiments and analyzed the data|wrote the manuscript|read, and approved the final manuscript	designed, performed experiments and analyzed the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5774168	29347977	RB	2	conceived the research work|designed, performed experiments and analyzed the data|wrote the manuscript|read, and approved the final manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5774168	29347977	RB	2	conceived the research work|designed, performed experiments and analyzed the data|wrote the manuscript|read, and approved the final manuscript	read, and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
1978533	17895990	CF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1978533	17895990	CF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1978533	17895990	CF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1978533	17895990	CF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1978533	17895990	CF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1978533	17895990	DS	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1978533	17895990	DS	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1978533	17895990	GG	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1978533	17895990	GG	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1978533	17895990	MR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1978533	17895990	MR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1978533	17895990	MR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1978533	17895990	MR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1978533	17895990	MR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1978533	17895990	SI	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1978533	17895990	SI	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1978533	17895990	SI	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418565	25938452	JWP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418565	25938452	JWP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418565	25938452	JWP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418565	25938452	JWP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418565	25938452	NAB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418565	25938452	NAB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418565	25938452	NAB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418565	25938452	PWP	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418565	25938452	PWP	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418565	25938452	PWP	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418565	25938452	TJP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418565	25938452	TJP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418565	25938452	TJP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418565	25938452	TJP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418565	25938452	TJP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418565	25938452	ZHE	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418565	25938452	ZHE	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418565	25938452	ZHE	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418565	25938452	ZHE	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3493971	23027341	AS	2	performed the statistical analysis|study concept, design and coordination	performed the statistical analysis	Analyzed the data	Formal analysis	YES
3493971	23027341	AS	2	performed the statistical analysis|study concept, design and coordination	study concept, design and coordination	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
3493971	23027341	BP	2	study concept, design and coordination	study concept, design and coordination	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
3493971	23027341	CL	2	study concept, design and coordination|contribution to data acquisition and interpretation	study concept, design and coordination	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
3493971	23027341	CL	2	study concept, design and coordination|contribution to data acquisition and interpretation	contribution to data acquisition and interpretation	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
3493971	23027341	DB	2	contributed in the sequence alignment	contributed in the sequence alignment	Performed the experiments	Investigation	YES
3493971	23027341	GL	2	contribution to data acquisition and interpretation	contribution to data acquisition and interpretation	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
3493971	23027341	GP	2	study concept, design and coordination	study concept, design and coordination	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
3493971	23027341	MEE	2	contributed in the sequence alignment|contribution to data acquisition and interpretation	contributed in the sequence alignment	Performed the experiments	Investigation	YES
3493971	23027341	MEE	2	contributed in the sequence alignment|contribution to data acquisition and interpretation	contribution to data acquisition and interpretation	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
3493971	23027341	VD	2	contributed in the sequence alignment|contribution to data acquisition and interpretation	contributed in the sequence alignment	Performed the experiments	Investigation	YES
3493971	23027341	VD	2	contributed in the sequence alignment|contribution to data acquisition and interpretation	contribution to data acquisition and interpretation	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5095545	28080992	C.A.C.	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5095545	28080992	C.A.C.	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5095545	28080992	D.A.H.	PLoS5	Conceived and designed the experiments|Analysed the sequencing data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5095545	28080992	D.A.H.	PLoS5	Conceived and designed the experiments|Analysed the sequencing data|Wrote the paper	Analysed the sequencing data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5095545	28080992	D.A.H.	PLoS5	Conceived and designed the experiments|Analysed the sequencing data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5095545	28080992	K.V.	PLoS5	Conceived and designed the experiments|Analysed the phenotypic data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5095545	28080992	K.V.	PLoS5	Conceived and designed the experiments|Analysed the phenotypic data|Wrote the paper	Analysed the phenotypic data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5095545	28080992	K.V.	PLoS5	Conceived and designed the experiments|Analysed the phenotypic data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5095545	28080992	M.C.F.	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5095545	28080992	M.C.F.	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5095545	28080992	R.A.F.	PLoS5	Conceived and designed the experiments|Analysed the sequencing data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5095545	28080992	R.A.F.	PLoS5	Conceived and designed the experiments|Analysed the sequencing data|Wrote the paper	Analysed the sequencing data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5095545	28080992	R.A.F.	PLoS5	Conceived and designed the experiments|Analysed the sequencing data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5095545	28080992	R.C.M.	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5095545	28080992	R.C.M.	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5095545	28080992	S.A.J.	PLoS5	Analysed the phenotypic data|Wrote the paper	Analysed the phenotypic data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5095545	28080992	S.A.J.	PLoS5	Analysed the phenotypic data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270779	25033057	All authors	PLoS52	contributed to and approved the final manuscript	contributed to and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6270779	25033057	CYH	PLoS52	analysed the data|performed experimental work and calculations	analysed the data	Analyzed the data	Formal analysis	YES
6270779	25033057	CYH	PLoS52	analysed the data|performed experimental work and calculations	performed experimental work and calculations	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270779	25033057	JF	PLoS52	analysed the data|performed experimental work and calculations	analysed the data	Analyzed the data	Formal analysis	YES
6270779	25033057	JF	PLoS52	analysed the data|performed experimental work and calculations	performed experimental work and calculations	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270779	25033057	JWS	PLoS52	analysed the data|performed experimental work and calculations	analysed the data	Analyzed the data	Formal analysis	YES
6270779	25033057	JWS	PLoS52	analysed the data|performed experimental work and calculations	performed experimental work and calculations	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270779	25033057	JYM	PLoS52	analysed the data|performed experimental work and calculations	analysed the data	Analyzed the data	Formal analysis	YES
6270779	25033057	JYM	PLoS52	analysed the data|performed experimental work and calculations	performed experimental work and calculations	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270779	25033057	MH	PLoS52	analysed the data|performed experimental work and calculations	analysed the data	Analyzed the data	Formal analysis	YES
6270779	25033057	MH	PLoS52	analysed the data|performed experimental work and calculations	performed experimental work and calculations	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270779	25033057	RF	PLoS52	analysed the data|performed experimental work and calculations	analysed the data	Analyzed the data	Formal analysis	YES
6270779	25033057	RF	PLoS52	analysed the data|performed experimental work and calculations	performed experimental work and calculations	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270779	25033057	XFZ	PLoS52	analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
6270779	25033057	XST	PLoS52	analysed the data|performed experimental work and calculations	analysed the data	Analyzed the data	Formal analysis	YES
6270779	25033057	XST	PLoS52	analysed the data|performed experimental work and calculations	performed experimental work and calculations	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270779	25033057	XYL	PLoS52	analysed the data|performed experimental work and calculations	analysed the data	Analyzed the data	Formal analysis	YES
6270779	25033057	XYL	PLoS52	analysed the data|performed experimental work and calculations	performed experimental work and calculations	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270779	25033057	YCC	PLoS52	analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
6270779	25033057	YW	PLoS52	analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
6270779	25033057	ZXZ	PLoS52	analysed the data|performed experimental work and calculations	analysed the data	Analyzed the data	Formal analysis	YES
6270779	25033057	ZXZ	PLoS52	analysed the data|performed experimental work and calculations	performed experimental work and calculations	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5817092	29491878	ES	2	commented on the manuscript	commented on the manuscript	-	-	NO
5817092	29491878	KL	2	commented on the manuscript	commented on the manuscript	-	-	NO
5817092	29491878	LE	2	performed most of the experiments, except the pgl1 construct building and transformation|wrote the manuscript	performed most of the experiments, except the pgl1 construct building and transformation	Performed the experiments	Investigation	YES
5817092	29491878	LE	2	performed most of the experiments, except the pgl1 construct building and transformation|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5815976	29453625	APGB	PLoS52	performed experiments and analysed the results	performed experiments and analysed the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5815976	29453625	ARA	PLoS52	performed experiments and analysed the results	performed experiments and analysed the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5815976	29453625	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5815976	29453625	BCC	PLoS52	performed experiments and analysed the results	performed experiments and analysed the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5815976	29453625	IGBC	PLoS52	performed experiments and analysed the results	performed experiments and analysed the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5815976	29453625	RGB	PLoS52	helped with the kinetics of sugar consumption|wrote the paper	helped with the kinetics of sugar consumption	-	-	NO
5815976	29453625	RGB	PLoS52	helped with the kinetics of sugar consumption|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5815976	29453625	SRCA	PLoS52	designed the study|wrote the paper	designed the study	Conceived and designed the experiments	Methodology	YES
5815976	29453625	SRCA	PLoS52	designed the study|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5815976	29453625	VRR	PLoS52	performed experiments and analysed the results	performed experiments and analysed the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5775545	29351737	JPE	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5775545	29351737	MBB	PLoS52	provided tortoise samples|wrote the paper	provided tortoise samples	Contributed reagents/materials/analysis tools	Resources	YES
5775545	29351737	MBB	PLoS52	provided tortoise samples|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5775545	29351737	SST	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
1978534	17896002	AC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1978534	17896002	BS	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1978534	17896002	BS	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1978534	17896002	CK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Models	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1978534	17896002	CK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Models	Performed the experiments	Performed the experiments	Investigation	YES
1978534	17896002	CK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Models	Analyzed the data	Analyzed the data	Formal analysis	YES
1978534	17896002	CK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Models	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1978534	17896002	CK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Models	Models	Performed the experiments	Methodology	YES
1978534	17896002	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1978534	17896002	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1978534	17896002	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1978534	17896002	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1978534	17896002	RA	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5817094	29491870	BL	PLoS52	conceived and designed the experiments|conducted and analyzed the experiments|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5817094	29491870	BL	PLoS52	conceived and designed the experiments|conducted and analyzed the experiments|wrote the paper	conducted and analyzed the experiments	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5817094	29491870	BL	PLoS52	conceived and designed the experiments|conducted and analyzed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5817094	29491870	BM	PLoS52	conducted and analyzed the experiments	conducted and analyzed the experiments	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5817094	29491870	GX	PLoS52	conceived and designed the experiments|conducted and analyzed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5817094	29491870	GX	PLoS52	conceived and designed the experiments|conducted and analyzed the experiments	conducted and analyzed the experiments	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5817094	29491870	KL	PLoS52	helped to analyze the data	helped to analyze the data	Analyzed the data	Formal analysis	YES
5817094	29491870	XG	PLoS52	conceived and designed the experiments|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5817094	29491870	XG	PLoS52	conceived and designed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5817094	29491870	XL	PLoS52	conducted and analyzed the experiments	conducted and analyzed the experiments	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5817094	29491870	ZW	PLoS52	conducted and analyzed the experiments	conducted and analyzed the experiments	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3493972	23027342	JW	2	contributed equally to this work	contributed equally to this work	-	-	NO
3493972	23027342	LW	2	contributed equally to this work	contributed equally to this work	-	-	NO
5815978	29453688	XHG	1	Planning and designing of the study	Planning and designing of the study	Conceived and designed the experiments	Methodology	YES
6425857	30997000	All authors	2	have given approval to the final version of the manuscript	have given approval to the final version of the manuscript	-	-	NO
5104500	27821530	M.S.	2	carried out the character analyses and drafted the paper	carried out the character analyses and drafted the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4418566	25938760	BPC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418566	25938760	HKS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4418566	25938760	HKS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418566	25938760	QH	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418566	25938760	YHL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418566	25938760	ZKL	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418566	25938760	ZKL	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418566	25938760	ZKL	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1978535	17895974	SU	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1978535	17895974	SU	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1978535	17895974	SU	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1978535	17895974	TM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1978535	17895974	TM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1978535	17895974	TM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3493973	23027343	all authors	2	contributed equally to the work	contributed equally to the work	-	-	NO
6270780	25120054	A.M.	2	synthesized and characterized the compounds	synthesized and characterized the compounds	Performed the experiments	Investigation	YES
6270780	25120054	A.M.G.	2	obtained and characterized the nanocomposites|designed the study	obtained and characterized the nanocomposites	Performed the experiments	Investigation	YES
6270780	25120054	A.M.G.	2	obtained and characterized the nanocomposites|designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
6270780	25120054	A.O.	2	obtained and characterized the nanocomposites	obtained and characterized the nanocomposites	Performed the experiments	Investigation	YES
6270780	25120054	B.G.	2	performed the viability tests	performed the viability tests	Performed the experiments	Investigation	YES
6270780	25120054	B.S.V.	2	obtained and characterized the nanocomposites	obtained and characterized the nanocomposites	Performed the experiments	Investigation	YES
6270780	25120054	C.L.	2	synthesized and characterized the compounds	synthesized and characterized the compounds	Performed the experiments	Investigation	YES
6270780	25120054	D.C.N.	2	synthesized and characterized the compounds	synthesized and characterized the compounds	Performed the experiments	Investigation	YES
6270780	25120054	G.P.	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
6270780	25120054	G.S.	2	obtained and characterized the nanocomposites	obtained and characterized the nanocomposites	Performed the experiments	Investigation	YES
6270780	25120054	L.M.	2	synthesized and characterized the compounds	synthesized and characterized the compounds	Performed the experiments	Investigation	YES
6270780	25120054	M.C.	2	performed the viability tests	performed the viability tests	Performed the experiments	Investigation	YES
6270780	25120054	M.C.C.	2	designed the study|interpreted the biological tests results	designed the study	Conceived and designed the experiments	Methodology	YES
6270780	25120054	M.C.C.	2	designed the study|interpreted the biological tests results	interpreted the biological tests results	Analyzed the data	Formal analysis	YES
6270780	25120054	M.T.C.	2	synthesized and characterized the compounds	synthesized and characterized the compounds	Performed the experiments	Investigation	YES
6270780	25120054	R.T.	2	obtained and characterized the nanocomposites	obtained and characterized the nanocomposites	Performed the experiments	Investigation	YES
6270780	25120054	V.G.	2	obtained and characterized the nanocomposites	obtained and characterized the nanocomposites	Performed the experiments	Investigation	YES
3888769	24459431	Wirat Rerksiri	2	contributed equally to this work	contributed equally to this work	-	-	NO
3888769	24459431	Xianwen Zhang	2	contributed equally to this work	contributed equally to this work	-	-	NO
5817096	29491874	AD	1	Acquisition of data|Analysis and interpretation of data	Acquisition of data	Performed the experiments	Investigation	YES
5817096	29491874	AD	1	Acquisition of data|Analysis and interpretation of data	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
5817096	29491874	CB	1	Acquisition of data|Analysis and interpretation of data	Acquisition of data	Performed the experiments	Investigation	YES
5817096	29491874	CB	1	Acquisition of data|Analysis and interpretation of data	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
5817096	29491874	CC	1	Acquisition of data|Analysis and interpretation of data	Acquisition of data	Performed the experiments	Investigation	YES
5817096	29491874	CC	1	Acquisition of data|Analysis and interpretation of data	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
5817096	29491874	GU	1	Study conception and design|Acquisition of data|Analysis and interpretation of data|Drafting of manuscript	Study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5817096	29491874	GU	1	Study conception and design|Acquisition of data|Analysis and interpretation of data|Drafting of manuscript	Acquisition of data	Performed the experiments	Investigation	YES
5817096	29491874	GU	1	Study conception and design|Acquisition of data|Analysis and interpretation of data|Drafting of manuscript	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
5817096	29491874	GU	1	Study conception and design|Acquisition of data|Analysis and interpretation of data|Drafting of manuscript	Drafting of manuscript	Wrote the paper	Writing - Original Draft	YES
5817096	29491874	SR	1	Study conception and design|Drafting of manuscript|Critical revision	Study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5817096	29491874	SR	1	Study conception and design|Drafting of manuscript|Critical revision	Drafting of manuscript	Wrote the paper	Writing - Original Draft	YES
5817096	29491874	SR	1	Study conception and design|Drafting of manuscript|Critical revision	Critical revision	Wrote the paper	Writing - Review & Editing	YES
5817096	29491874	TH	1	Study conception and design|Acquisition of data|Analysis and interpretation of data|Drafting of manuscript	Study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5817096	29491874	TH	1	Study conception and design|Acquisition of data|Analysis and interpretation of data|Drafting of manuscript	Acquisition of data	Performed the experiments	Investigation	YES
5817096	29491874	TH	1	Study conception and design|Acquisition of data|Analysis and interpretation of data|Drafting of manuscript	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
5817096	29491874	TH	1	Study conception and design|Acquisition of data|Analysis and interpretation of data|Drafting of manuscript	Drafting of manuscript	Wrote the paper	Writing - Original Draft	YES
5818386	29460184	ARA	2	carried out work the bioinformatics analysis	carried out work the bioinformatics analysis	Performed the experiments	Formal analysis|Investigation	YES
5818386	29460184	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5818386	29460184	MAH	2	developed hypothesis, supervised the whole work and helped to prepare the manuscript	developed hypothesis, supervised the whole work and helped to prepare the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Supervision|Writing - Original Draft	YES
5818386	29460184	MAS	2	carried out work the bioinformatics analysis	carried out work the bioinformatics analysis	Performed the experiments	Formal analysis|Investigation	YES
5818386	29460184	MH	2	developed hypothesis, supervised the whole work and helped to prepare the manuscript	developed hypothesis, supervised the whole work and helped to prepare the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Supervision|Writing - Original Draft	YES
5818386	29460184	MIH	2	carried out work the bioinformatics analysis	carried out work the bioinformatics analysis	Performed the experiments	Formal analysis|Investigation	YES
5818386	29460184	MS	2	partially carried out work on bench and helped to draft the manuscript	partially carried out work on bench and helped to draft the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5818386	29460184	Mouth Disease Vaccine	2	biofilm formation, and heavy metal resistance in bacteria	biofilm formation, and heavy metal resistance in bacteria	-	-	NO
5818386	29460184	SPN	2	partially carried out work on bench and helped to draft the manuscript	partially carried out work on bench and helped to draft the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5818386	29460184	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
4418567	25938233	AM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418567	25938233	AM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418567	25938233	AM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418567	25938233	IS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418567	25938233	IS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418567	25938233	IS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418567	25938233	IS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418567	25938233	JB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418567	25938233	MA	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418567	25938233	RW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418567	25938233	SFH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418567	25938233	SFH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418567	25938233	SFH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418567	25938233	SFH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418567	25938233	SFH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418567	25938233	SJT-W	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418567	25938233	SM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418567	25938233	SM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418567	25938233	SM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418567	25938233	SM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1978536	17895996	AA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1978536	17895996	AA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1978536	17895996	AA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1978536	17895996	AA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1978536	17895996	AA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1978536	17895996	IM	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1978536	17895996	IM	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1978536	17895996	JY	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1978536	17895996	KO	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1978536	17895996	KO	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1978536	17895996	KO	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1978536	17895996	KO	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4637456	26587542	Chengjin Zhang	PLoS52	conceived and designed the experiments|analyzed the data|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4637456	26587542	Chengjin Zhang	PLoS52	conceived and designed the experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
4637456	26587542	Chengjin Zhang	PLoS52	conceived and designed the experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4637456	26587542	Lina Zhang	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4637456	26587542	Lina Zhang	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
4637456	26587542	Lina Zhang	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
4637456	26587542	Lina Zhang	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4637456	26587542	Rui Gao	PLoS52	analyzed the data|contributed reagents/materials/analysis tools|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
4637456	26587542	Rui Gao	PLoS52	analyzed the data|contributed reagents/materials/analysis tools|wrote the paper	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4637456	26587542	Rui Gao	PLoS52	analyzed the data|contributed reagents/materials/analysis tools|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4637456	26587542	Runtao Yang	PLoS52	performed the experiments|contributed reagents/materials/analysis tools|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
4637456	26587542	Runtao Yang	PLoS52	performed the experiments|contributed reagents/materials/analysis tools|wrote the paper	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4637456	26587542	Runtao Yang	PLoS52	performed the experiments|contributed reagents/materials/analysis tools|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3491834	22987724	CS	PLoS52	designed the experiments|performed the experiments|analysed data|wrote the paper	designed the experiments	Conceived and designed the experiments	Methodology	YES
3491834	22987724	CS	PLoS52	designed the experiments|performed the experiments|analysed data|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
3491834	22987724	CS	PLoS52	designed the experiments|performed the experiments|analysed data|wrote the paper	analysed data	Analyzed the data	Formal analysis	YES
3491834	22987724	CS	PLoS52	designed the experiments|performed the experiments|analysed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3491834	22987724	FP	PLoS52	designed the experiments|performed the experiments|analysed data|wrote the paper	designed the experiments	Conceived and designed the experiments	Methodology	YES
3491834	22987724	FP	PLoS52	designed the experiments|performed the experiments|analysed data|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
3491834	22987724	FP	PLoS52	designed the experiments|performed the experiments|analysed data|wrote the paper	analysed data	Analyzed the data	Formal analysis	YES
3491834	22987724	FP	PLoS52	designed the experiments|performed the experiments|analysed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3491834	22987724	JN	PLoS52	designed the experiments|performed the experiments|analysed data	designed the experiments	Conceived and designed the experiments	Methodology	YES
3491834	22987724	JN	PLoS52	designed the experiments|performed the experiments|analysed data	performed the experiments	Performed the experiments	Investigation	YES
3491834	22987724	JN	PLoS52	designed the experiments|performed the experiments|analysed data	analysed data	Analyzed the data	Formal analysis	YES
3491834	22987724	KHA	PLoS52	analysed data|contributed reagents	analysed data	Analyzed the data	Formal analysis	YES
3491834	22987724	KHA	PLoS52	analysed data|contributed reagents	contributed reagents	Contributed reagents/materials/analysis tools	Resources	YES
3491834	22987724	RCH	PLoS52	designed the experiments|performed the experiments|analysed data|wrote the paper	designed the experiments	Conceived and designed the experiments	Methodology	YES
3491834	22987724	RCH	PLoS52	designed the experiments|performed the experiments|analysed data|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
3491834	22987724	RCH	PLoS52	designed the experiments|performed the experiments|analysed data|wrote the paper	analysed data	Analyzed the data	Formal analysis	YES
3491834	22987724	RCH	PLoS52	designed the experiments|performed the experiments|analysed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3491834	22987724	RM	PLoS52	analysed data	analysed data	Analyzed the data	Formal analysis	YES
3491834	22987724	SB	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
3491834	22987724	SM	PLoS52	designed the experiments|performed the experiments|analysed data	designed the experiments	Conceived and designed the experiments	Methodology	YES
3491834	22987724	SM	PLoS52	designed the experiments|performed the experiments|analysed data	performed the experiments	Performed the experiments	Investigation	YES
3491834	22987724	SM	PLoS52	designed the experiments|performed the experiments|analysed data	analysed data	Analyzed the data	Formal analysis	YES
3491834	22987724	STC	PLoS52	designed the experiments|analysed data|wrote the paper	designed the experiments	Conceived and designed the experiments	Methodology	YES
3491834	22987724	STC	PLoS52	designed the experiments|analysed data|wrote the paper	analysed data	Analyzed the data	Formal analysis	YES
3491834	22987724	STC	PLoS52	designed the experiments|analysed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3491834	22987724	SU	PLoS52	analysed data	analysed data	Analyzed the data	Formal analysis	YES
5775551	29351731	BX	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5775551	29351731	FS	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5775551	29351731	GC	PLoS52	annotated and analyzed the sequences|designed the experiments|cloned the nucleotide sequences|conducted alternative splicing analyses|performed performed the computational analysis of expression level|analyzed promoter activity|analyzed the data	annotated and analyzed the sequences	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5775551	29351731	GC	PLoS52	annotated and analyzed the sequences|designed the experiments|cloned the nucleotide sequences|conducted alternative splicing analyses|performed performed the computational analysis of expression level|analyzed promoter activity|analyzed the data	designed the experiments	Conceived and designed the experiments	Methodology	YES
5775551	29351731	GC	PLoS52	annotated and analyzed the sequences|designed the experiments|cloned the nucleotide sequences|conducted alternative splicing analyses|performed performed the computational analysis of expression level|analyzed promoter activity|analyzed the data	cloned the nucleotide sequences	Performed the experiments	Investigation	YES
5775551	29351731	GC	PLoS52	annotated and analyzed the sequences|designed the experiments|cloned the nucleotide sequences|conducted alternative splicing analyses|performed performed the computational analysis of expression level|analyzed promoter activity|analyzed the data	conducted alternative splicing analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5775551	29351731	GC	PLoS52	annotated and analyzed the sequences|designed the experiments|cloned the nucleotide sequences|conducted alternative splicing analyses|performed performed the computational analysis of expression level|analyzed promoter activity|analyzed the data	performed performed the computational analysis of expression level	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5775551	29351731	GC	PLoS52	annotated and analyzed the sequences|designed the experiments|cloned the nucleotide sequences|conducted alternative splicing analyses|performed performed the computational analysis of expression level|analyzed promoter activity|analyzed the data	analyzed promoter activity	Analyzed the data	Formal analysis	YES
5775551	29351731	GC	PLoS52	annotated and analyzed the sequences|designed the experiments|cloned the nucleotide sequences|conducted alternative splicing analyses|performed performed the computational analysis of expression level|analyzed promoter activity|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5775551	29351731	HD	PLoS52	annotated and analyzed the sequences	annotated and analyzed the sequences	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5775551	29351731	HL	PLoS52	annotated and analyzed the sequences	annotated and analyzed the sequences	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5775551	29351731	HM	PLoS52	annotated and analyzed the sequences	annotated and analyzed the sequences	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5775551	29351731	JZ	PLoS52	annotated and analyzed the sequences|conducted phylogenetic and evolutionary analysis|analyzed promoter activity	annotated and analyzed the sequences	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5775551	29351731	JZ	PLoS52	annotated and analyzed the sequences|conducted phylogenetic and evolutionary analysis|analyzed promoter activity	conducted phylogenetic and evolutionary analysis	Performed the experiments	Investigation	YES
5775551	29351731	JZ	PLoS52	annotated and analyzed the sequences|conducted phylogenetic and evolutionary analysis|analyzed promoter activity	analyzed promoter activity	Analyzed the data	Formal analysis	YES
5775551	29351731	PG	PLoS52	cloned the nucleotide sequences	cloned the nucleotide sequences	Performed the experiments	Investigation	YES
5775551	29351731	SC	PLoS52	annotated and analyzed the sequences	annotated and analyzed the sequences	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5775551	29351731	SH	PLoS52	designed the experiments|cloned the nucleotide sequences|conducted alternative splicing analyses|analyzed exon junction|analyzed the data	designed the experiments	Conceived and designed the experiments	Methodology	YES
5775551	29351731	SH	PLoS52	designed the experiments|cloned the nucleotide sequences|conducted alternative splicing analyses|analyzed exon junction|analyzed the data	cloned the nucleotide sequences	Performed the experiments	Investigation	YES
5775551	29351731	SH	PLoS52	designed the experiments|cloned the nucleotide sequences|conducted alternative splicing analyses|analyzed exon junction|analyzed the data	conducted alternative splicing analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5775551	29351731	SH	PLoS52	designed the experiments|cloned the nucleotide sequences|conducted alternative splicing analyses|analyzed exon junction|analyzed the data	analyzed exon junction	Analyzed the data	Formal analysis	YES
5775551	29351731	SH	PLoS52	designed the experiments|cloned the nucleotide sequences|conducted alternative splicing analyses|analyzed exon junction|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5775551	29351731	WH	PLoS52	cloned the nucleotide sequences	cloned the nucleotide sequences	Performed the experiments	Investigation	YES
5775551	29351731	YJ	PLoS52	conceived of this project|designed the experiments|performed data correlations|analyzed the data|wrote the manuscript	conceived of this project	Conceived and designed the experiments	Conceptualization	YES
5775551	29351731	YJ	PLoS52	conceived of this project|designed the experiments|performed data correlations|analyzed the data|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5775551	29351731	YJ	PLoS52	conceived of this project|designed the experiments|performed data correlations|analyzed the data|wrote the manuscript	performed data correlations	-	-	NO
5775551	29351731	YJ	PLoS52	conceived of this project|designed the experiments|performed data correlations|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5775551	29351731	YJ	PLoS52	conceived of this project|designed the experiments|performed data correlations|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5775551	29351731	YM	PLoS52	analyzed exon junction|performed performed the computational analysis of expression level|performed data correlations|analyzed the data|wrote the manuscript	analyzed exon junction	Analyzed the data	Formal analysis	YES
5775551	29351731	YM	PLoS52	analyzed exon junction|performed performed the computational analysis of expression level|performed data correlations|analyzed the data|wrote the manuscript	performed performed the computational analysis of expression level	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5775551	29351731	YM	PLoS52	analyzed exon junction|performed performed the computational analysis of expression level|performed data correlations|analyzed the data|wrote the manuscript	performed data correlations	-	-	NO
5775551	29351731	YM	PLoS52	analyzed exon junction|performed performed the computational analysis of expression level|performed data correlations|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5775551	29351731	YM	PLoS52	analyzed exon junction|performed performed the computational analysis of expression level|performed data correlations|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5775551	29351731	YS	PLoS52	annotated and analyzed the sequences|conducted phylogenetic and evolutionary analysis|analyzed the data	annotated and analyzed the sequences	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5775551	29351731	YS	PLoS52	annotated and analyzed the sequences|conducted phylogenetic and evolutionary analysis|analyzed the data	conducted phylogenetic and evolutionary analysis	Performed the experiments	Investigation	YES
5775551	29351731	YS	PLoS52	annotated and analyzed the sequences|conducted phylogenetic and evolutionary analysis|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5775551	29351731	YW	PLoS52	annotated and analyzed the sequences	annotated and analyzed the sequences	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5775551	29351731	all authors	PLoS52	discussed the results and commented on the manuscript	discussed the results and commented on the manuscript	-	-	NO
5104504	27821534	A.L.S.	PLoS52	conceived and designed the experiments|performed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5104504	27821534	A.L.S.	PLoS52	conceived and designed the experiments|performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5104504	27821534	A.W.S.	PLoS52	provided scientific guidance and advice	provided scientific guidance and advice	-	Supervision	YES
5104504	27821534	B.B.	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5104504	27821534	D.C.C.	PLoS52	conceived and designed the experiments|performed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5104504	27821534	D.C.C.	PLoS52	conceived and designed the experiments|performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5104504	27821534	J.H.R.	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5104504	27821534	M.R.A.	PLoS52	conceived and designed the experiments|performed the experiments|performed data analysis	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5104504	27821534	M.R.A.	PLoS52	conceived and designed the experiments|performed the experiments|performed data analysis	performed the experiments	Performed the experiments	Investigation	YES
5104504	27821534	M.R.A.	PLoS52	conceived and designed the experiments|performed the experiments|performed data analysis	performed data analysis	Analyzed the data	Formal analysis	YES
5104504	27821534	P.M.J.	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5104504	27821534	Y.T.C.	PLoS52	performed data analysis	performed data analysis	Analyzed the data	Formal analysis	YES
4418568	25938458	AK	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418568	25938458	DS	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418568	25938458	HB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418568	25938458	HB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418568	25938458	HB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418568	25938458	HB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418568	25938458	PM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418568	25938458	PM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418568	25938458	PM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418568	25938458	PM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418568	25938458	YY	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5817336	29491880	PT	2	contributed to the experimental design and manuscript revision	contributed to the experimental design and manuscript revision	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
5817336	29491880	SL	2	designed the both experiments, conducted the flume experiment, analyzed the data, and drafted the manuscript	designed the both experiments, conducted the flume experiment, analyzed the data, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5817336	29491880	SY	2	designed the both experiments, conducted the flume experiment, analyzed the data, and drafted the manuscript	designed the both experiments, conducted the flume experiment, analyzed the data, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5817336	29491880	TB	2	contributed to the experimental design and manuscript revision	contributed to the experimental design and manuscript revision	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
5817336	29491880	TP	2	designed and conducted the mesocosm experiment, and contributed to manuscript revision	designed and conducted the mesocosm experiment, and contributed to manuscript revision	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
5818389	29460231	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5818389	29460231	FH	2	carried out the microbiological testing and drafted the manuscript|conceived of the study, and participated in its design and coordination and helped to draft the manuscript	carried out the microbiological testing and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5818389	29460231	FH	2	carried out the microbiological testing and drafted the manuscript|conceived of the study, and participated in its design and coordination and helped to draft the manuscript	conceived of the study, and participated in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
5818389	29460231	HG	2	carried out the microbiological testing and drafted the manuscript|conceived of the study, and participated in its design and coordination and helped to draft the manuscript	carried out the microbiological testing and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5818389	29460231	HG	2	carried out the microbiological testing and drafted the manuscript|conceived of the study, and participated in its design and coordination and helped to draft the manuscript	conceived of the study, and participated in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
5818389	29460231	MH	2	carried out the microbiological testing and drafted the manuscript|conceived of the study, and participated in its design and coordination and helped to draft the manuscript	carried out the microbiological testing and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5818389	29460231	MH	2	carried out the microbiological testing and drafted the manuscript|conceived of the study, and participated in its design and coordination and helped to draft the manuscript	conceived of the study, and participated in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
5818389	29460231	NH	2	conceived of the study, and participated in its design and coordination and helped to draft the manuscript	conceived of the study, and participated in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
5818389	29460231	WM	2	conceived of the study, and participated in its design and coordination and helped to draft the manuscript	conceived of the study, and participated in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
5104510	27821523	A.H.	PLoS52	designed the study|edited the text	designed the study	Conceived and designed the experiments	Methodology	YES
5104510	27821523	A.H.	PLoS52	designed the study|edited the text	edited the text	Wrote the paper	Writing - Review & Editing	YES
5104510	27821523	All authors	PLoS52	analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
5104510	27821523	B.C.V.	PLoS52	conducted the live microscopy analysis of bryozoan development|edited the text	conducted the live microscopy analysis of bryozoan development	Performed the experiments	Investigation	YES
5104510	27821523	B.C.V.	PLoS52	conducted the live microscopy analysis of bryozoan development|edited the text	edited the text	Wrote the paper	Writing - Review & Editing	YES
5104510	27821523	J.M.M.-D.	PLoS52	designed the study|carried out the gene expression analyses	designed the study	Conceived and designed the experiments	Methodology	YES
5104510	27821523	J.M.M.-D.	PLoS52	designed the study|carried out the gene expression analyses	carried out the gene expression analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4418569	25938494	BYL	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418569	25938494	BYL	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418569	25938494	CA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418569	25938494	CA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418569	25938494	CA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418569	25938494	CA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418569	25938494	DBCW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418569	25938494	DBCW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418569	25938494	DBCW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418569	25938494	DBCW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418569	25938494	KTW	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418569	25938494	KTW	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418569	25938494	LST	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418569	25938494	LST	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418569	25938494	LST	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418569	25938494	LST	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418569	25938494	LST	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418569	25938494	PSML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418569	25938494	PSML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418569	25938494	PSML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418569	25938494	PSML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418569	25938494	PSML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270781	25517342	AL	PLoS52	designed research|performed research|analyzed the data	designed research	Conceived and designed the experiments	Methodology	YES
6270781	25517342	AL	PLoS52	designed research|performed research|analyzed the data	performed research	Performed the experiments	Investigation	YES
6270781	25517342	AL	PLoS52	designed research|performed research|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
6270781	25517342	CGB	PLoS52	designed research|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
6270781	25517342	CGB	PLoS52	designed research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270781	25517342	GFB	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
6270781	25517342	LA	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
6270781	25517342	MP	PLoS52	designed research|analyzed the data|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
6270781	25517342	MP	PLoS52	designed research|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
6270781	25517342	MP	PLoS52	designed research|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5817422	29491872	All authors	PLoS52	conceived the project	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5817422	29491872	C-FH	PLoS52	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5817422	29491872	JG	PLoS52	performed the experiments|helped to analyze the data and write the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5817422	29491872	JG	PLoS52	performed the experiments|helped to analyze the data and write the manuscript	helped to analyze the data and write the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5817422	29491872	LL	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5817422	29491872	LW	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5817422	29491872	MC	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5817422	29491872	YZ	PLoS52	performed the experiments|helped to analyze the data and write the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5817422	29491872	YZ	PLoS52	performed the experiments|helped to analyze the data and write the manuscript	helped to analyze the data and write the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5826908	29484505	All	2	animal experiment procedures were conducted in accordance with the guidelines of the animal welfare act and protocols were approved by the institutional animal care and use committee of the south china agriculture university	animal experiment procedures were conducted in accordance with the guidelines of the animal welfare act and protocols were approved by the institutional animal care and use committee of the south china agriculture university	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5826908	29484505	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5826908	29484505	BC	2	contributed to the sample collection, data analysis and manuscript writing	contributed to the sample collection, data analysis and manuscript writing	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft	YES
5826908	29484505	Heizhao Lin	2	for their material supports and kind helps in many aspects	for their material supports and kind helps in many aspects	-	-	NO
5826908	29484505	LG	2	contributed to fish feeding and samples collection	contributed to fish feeding and samples collection	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5826908	29484505	QP	2	contributed to experimental design and manuscript writing	contributed to experimental design and manuscript writing	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5826908	29484505	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5826908	29484505	Zhong Huang	2	for their material supports and kind helps in many aspects	for their material supports and kind helps in many aspects	-	-	NO
3491835	23027611	AD	2	performed behavioural studies	performed behavioural studies	Performed the experiments	Investigation	YES
3491835	23027611	CMC	2	designed the experiments and supervised the study	designed the experiments and supervised the study	Conceived and designed the experiments	Methodology|Supervision	YES
3491835	23027611	DH	2	analysed mtor activity in brain microdiscs	analysed mtor activity in brain microdiscs	-	-	NO
3491835	23027611	DW	2	performed behavioural studies	performed behavioural studies	Performed the experiments	Investigation	YES
3491835	23027611	FG	2	performed proteomic analysis, biochemistry and cell biology experiments	performed proteomic analysis, biochemistry and cell biology experiments	Performed the experiments	Investigation	YES
3491835	23027611	FL	2	performed behavioural studies	performed behavioural studies	Performed the experiments	Investigation	YES
3491835	23027611	JB	2	designed the experiments and supervised the study	designed the experiments and supervised the study	Conceived and designed the experiments	Methodology|Supervision	YES
3491835	23027611	JM	2	performed proteomic analysis, biochemistry and cell biology experiments	performed proteomic analysis, biochemistry and cell biology experiments	Performed the experiments	Investigation	YES
3491835	23027611	JMR	2	performed behavioural studies	performed behavioural studies	Performed the experiments	Investigation	YES
3491835	23027611	KF	2	designed the experiments and supervised the study	designed the experiments and supervised the study	Conceived and designed the experiments	Methodology|Supervision	YES
3491835	23027611	MJM	2	designed the experiments and supervised the study|wrote the manuscript	designed the experiments and supervised the study	Conceived and designed the experiments	Methodology|Supervision	YES
3491835	23027611	MJM	2	designed the experiments and supervised the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3491835	23027611	MS	2	performed protein identification and validation by mass spectrometry	performed protein identification and validation by mass spectrometry	Performed the experiments	Investigation|Validation	YES
3491835	23027611	PD	2	performed proteomic analysis, biochemistry and cell biology experiments	performed proteomic analysis, biochemistry and cell biology experiments	Performed the experiments	Investigation	YES
3491835	23027611	PM	2	designed the experiments and supervised the study|wrote the manuscript	designed the experiments and supervised the study	Conceived and designed the experiments	Methodology|Supervision	YES
3491835	23027611	PM	2	designed the experiments and supervised the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3491835	23027611	SCD	2	performed proteomic analysis, biochemistry and cell biology experiments	performed proteomic analysis, biochemistry and cell biology experiments	Performed the experiments	Investigation	YES
1978537	17912349	JY	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1978537	17912349	JY	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1978537	17912349	JY	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1978537	17912349	MN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1978537	17912349	MN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1978537	17912349	MN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1978537	17912349	MN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1978537	17912349	MN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5775586	29351733	AGG	2	designed the research|performed sequence analysis and phylogenetic studies	designed the research	Conceived and designed the experiments	Methodology	YES
5775586	29351733	AGG	2	designed the research|performed sequence analysis and phylogenetic studies	performed sequence analysis and phylogenetic studies	Performed the experiments	Investigation	YES
5775586	29351733	CA	2	designed the research|wrote the article	designed the research	Conceived and designed the experiments	Methodology	YES
5775586	29351733	CA	2	designed the research|wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
5775586	29351733	FMC	2	wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
4418570	25938409	ARRP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418570	25938409	ARRP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418570	25938409	ARRP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418570	25938409	ARRP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418570	25938409	ARRP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418570	25938409	BG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418570	25938409	BG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418570	25938409	BG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418570	25938409	BP	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418570	25938409	BP	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418570	25938409	BP	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418570	25938409	FB	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418570	25938409	FB	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418570	25938409	FB	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418570	25938409	JD	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418570	25938409	JD	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418570	25938409	RB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418570	25938409	RB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418570	25938409	RB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418570	25938409	RB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418570	25938409	RB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418570	25938409	SA	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418570	25938409	SA	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418570	25938409	SA	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270782	25123184	All authors	PLoS52	contributed to this study	contributed to this study	-	-	NO
6270782	25123184	H. Jun	PLoS52	contributed to the interpretation and statistical analysis of the data	contributed to the interpretation and statistical analysis of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6270782	25123184	H. Jung	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
6270782	25123184	S. Kim	PLoS52	conceived and designed the experiments|wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6270782	25123184	S. Kim	PLoS52	conceived and designed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5833332	29492704	All	2	data generated or analyzed during this study are included in this published article	data generated or analyzed during this study are included in this published article	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5833332	29492704	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5833332	29492704	HX	2	analyzed the results	analyzed the results	Analyzed the data	Formal analysis	YES
5833332	29492704	RW	2	preformed the experiments	preformed the experiments	Performed the experiments	Investigation	YES
5833332	29492704	The authors	2	declare that they have no competing interests|give their consent for publication	declare that they have no competing interests	-	-	NO
5833332	29492704	The authors	2	declare that they have no competing interests|give their consent for publication	give their consent for publication	-	-	NO
5833332	29492704	WY	2	designed the experiments|wrote the manuscript which was reviewed and approved by all authors	designed the experiments	Conceived and designed the experiments	Methodology	YES
5833332	29492704	WY	2	designed the experiments|wrote the manuscript which was reviewed and approved by all authors	wrote the manuscript which was reviewed and approved by all authors	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5833332	29492704	XH	2	preformed the experiments	preformed the experiments	Performed the experiments	Investigation	YES
5833332	29492704	ZS	2	designed the experiments|analyzed the results|wrote the manuscript which was reviewed and approved by all authors	designed the experiments	Conceived and designed the experiments	Methodology	YES
5833332	29492704	ZS	2	designed the experiments|analyzed the results|wrote the manuscript which was reviewed and approved by all authors	analyzed the results	Analyzed the data	Formal analysis	YES
5833332	29492704	ZS	2	designed the experiments|analyzed the results|wrote the manuscript which was reviewed and approved by all authors	wrote the manuscript which was reviewed and approved by all authors	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3491836	22933323	All authors	2	commented on the manuscript	commented on the manuscript	-	-	NO
3491836	22933323	CAH	2	initiated the study, planned experiments and wrote the paper	initiated the study, planned experiments and wrote the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
3491836	22933323	DE	2	initiated the study, planned experiments and wrote the paper	initiated the study, planned experiments and wrote the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5775594	29351734	A.L.	2	conceived the work|designed the web interface	conceived the work	Conceived and designed the experiments	Conceptualization	YES
5775594	29351734	A.L.	2	conceived the work|designed the web interface	designed the web interface	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
5775594	29351734	J.X.	2	designed the database schema|designed the web interface	designed the database schema	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
5775594	29351734	J.X.	2	designed the database schema|designed the web interface	designed the web interface	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
5775594	29351734	R.W.	2	designed the web interface|wrote the manuscript	designed the web interface	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
5775594	29351734	R.W.	2	designed the web interface|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5775594	29351734	W.M.	2	conceived the work|designed the database schema|designed the web interface	conceived the work	Conceived and designed the experiments	Conceptualization	YES
5775594	29351734	W.M.	2	conceived the work|designed the database schema|designed the web interface	designed the database schema	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
5775594	29351734	W.M.	2	conceived the work|designed the database schema|designed the web interface	designed the web interface	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
5775594	29351734	W.W.	2	designed the web interface	designed the web interface	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
1978538	17895999	CA	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1978538	17895999	CN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1978538	17895999	CN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1978538	17895999	CN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1978538	17895999	DW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1978538	17895999	EP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1978538	17895999	EP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1978538	17895999	EP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1978538	17895999	EP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1978538	17895999	EP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1978538	17895999	JA	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1978538	17895999	JA	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1978538	17895999	JM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1978538	17895999	MG	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1978538	17895999	MG	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1978538	17895999	RK	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
3493977	23027347	All authors	2	have reviewed and contributed to the different draft versions of the manuscript and have read and approved the final manuscript	have reviewed and contributed to the different draft versions of the manuscript and have read and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3493977	23027347	CAC	2	study design|contributed especifically to microscopic analysis procedures	study design	Conceived and designed the experiments	Methodology	YES
3493977	23027347	CAC	2	study design|contributed especifically to microscopic analysis procedures	contributed especifically to microscopic analysis procedures	Performed the experiments	Investigation	YES
3493977	23027347	DSB	2	experimental procedures, immunohistochemical processing, microscopic analysis, data collection and/or preparation of figures	experimental procedures, immunohistochemical processing, microscopic analysis, data collection and/or preparation of figures	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation|Visualization	YES
3493977	23027347	EE	2	experimental procedures, immunohistochemical processing, microscopic analysis, data collection and/or preparation of figures	experimental procedures, immunohistochemical processing, microscopic analysis, data collection and/or preparation of figures	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation|Visualization	YES
3493977	23027347	JAB	2	study design|contributed especifically to microscopic analysis procedures	study design	Conceived and designed the experiments	Methodology	YES
3493977	23027347	JAB	2	study design|contributed especifically to microscopic analysis procedures	contributed especifically to microscopic analysis procedures	Performed the experiments	Investigation	YES
3493977	23027347	JPD	2	study design|experimental procedures, immunohistochemical processing, microscopic analysis, data collection and/or preparation of figures	study design	Conceived and designed the experiments	Methodology	YES
3493977	23027347	JPD	2	study design|experimental procedures, immunohistochemical processing, microscopic analysis, data collection and/or preparation of figures	experimental procedures, immunohistochemical processing, microscopic analysis, data collection and/or preparation of figures	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation|Visualization	YES
3493977	23027347	KRT	2	experimental procedures, immunohistochemical processing, microscopic analysis, data collection and/or preparation of figures	experimental procedures, immunohistochemical processing, microscopic analysis, data collection and/or preparation of figures	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation|Visualization	YES
3493977	23027347	RJCR	2	experimental procedures, immunohistochemical processing, microscopic analysis, data collection and/or preparation of figures	experimental procedures, immunohistochemical processing, microscopic analysis, data collection and/or preparation of figures	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation|Visualization	YES
5817626	29491875	All authors	2	approved the final version of the manuscript	approved the final version of the manuscript	-	-	NO
5817626	29491875	all the authors	2	contributed with the carried out the bioinformatic analysis of the data and wrote the article with the	contributed with the carried out the bioinformatic analysis of the data and wrote the article with the	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft	YES
4418571	25938430	JFK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418571	25938430	JFK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4418571	25938430	JFK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418571	25938430	MS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418571	25938430	MS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418571	25938430	MS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418571	25938430	NMPB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418571	25938430	NMPB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418571	25938430	NMPB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418571	25938430	SC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418571	25938430	SC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418571	25938430	SC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418571	25938430	SDC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418571	25938430	SDC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418571	25938430	SDC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418571	25938430	SDC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418571	25938430	SDC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418571	25938430	WvdZ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418571	25938430	WvdZ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418571	25938430	WvdZ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5124077	27872370	A.P.	2	designed the model and experimental study|contributed to the drafting and revision of the article, and all authors approved the final version	designed the model and experimental study	Conceived and designed the experiments|Performed the experiments	Methodology	YES
5124077	27872370	A.P.	2	designed the model and experimental study|contributed to the drafting and revision of the article, and all authors approved the final version	contributed to the drafting and revision of the article, and all authors approved the final version	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5124077	27872370	A.S.	2	contributed to the drafting and revision of the article, and all authors approved the final version	contributed to the drafting and revision of the article, and all authors approved the final version	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5124077	27872370	E.W.	2	designed the model and experimental study|contributed to the drafting and revision of the article, and all authors approved the final version	designed the model and experimental study	Conceived and designed the experiments|Performed the experiments	Methodology	YES
5124077	27872370	E.W.	2	designed the model and experimental study|contributed to the drafting and revision of the article, and all authors approved the final version	contributed to the drafting and revision of the article, and all authors approved the final version	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5124077	27872370	K.Sm	2	designed the model and experimental study|contributed to the drafting and revision of the article, and all authors approved the final version	designed the model and experimental study	Conceived and designed the experiments|Performed the experiments	Methodology	YES
5124077	27872370	K.Sm	2	designed the model and experimental study|contributed to the drafting and revision of the article, and all authors approved the final version	contributed to the drafting and revision of the article, and all authors approved the final version	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5124077	27872370	K.Sw	2	collected all experimental data	collected all experimental data	Performed the experiments	Investigation	YES
5124077	27872370	O.F.	2	contributed to the drafting and revision of the article, and all authors approved the final version	contributed to the drafting and revision of the article, and all authors approved the final version	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5833890	29492783	All	PLoS52	data are fully available without restriction|applicable international, national, and/or institutional guidelines for the care and use of animals were followed|animal study protocols were approved by the vanderbilt university institutional animal care and use committee	data are fully available without restriction	-	-	NO
5833890	29492783	All	PLoS52	data are fully available without restriction|applicable international, national, and/or institutional guidelines for the care and use of animals were followed|animal study protocols were approved by the vanderbilt university institutional animal care and use committee	applicable international, national, and/or institutional guidelines for the care and use of animals were followed	-	-	NO
5833890	29492783	All	PLoS52	data are fully available without restriction|applicable international, national, and/or institutional guidelines for the care and use of animals were followed|animal study protocols were approved by the vanderbilt university institutional animal care and use committee	animal study protocols were approved by the vanderbilt university institutional animal care and use committee	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5833890	29492783	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5833890	29492783	HC	PLoS52	conceived and designed the study|reviewed and edited the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5833890	29492783	HC	PLoS52	conceived and designed the study|reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5833890	29492783	HL	PLoS52	conceived and designed the study|reviewed and edited the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5833890	29492783	HL	PLoS52	conceived and designed the study|reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5833890	29492783	QJ	PLoS52	performed the experiments|wrote the paper|reviewed and edited the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5833890	29492783	QJ	PLoS52	performed the experiments|wrote the paper|reviewed and edited the manuscript	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5833890	29492783	QJ	PLoS52	performed the experiments|wrote the paper|reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5833890	29492783	Thanks Carla Roberts	PLoS52	for her professional writing services	for her professional writing services	Wrote the paper	-	YES
5833890	29492783	The authors	PLoS52	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5833890	29492783	XH	PLoS52	performed the experiments|wrote the paper|reviewed and edited the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5833890	29492783	XH	PLoS52	performed the experiments|wrote the paper|reviewed and edited the manuscript	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5833890	29492783	XH	PLoS52	performed the experiments|wrote the paper|reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5833890	29492783	YD	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5833890	29492783	YZ	PLoS52	performed the experiments|wrote the paper|reviewed and edited the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5833890	29492783	YZ	PLoS52	performed the experiments|wrote the paper|reviewed and edited the manuscript	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5833890	29492783	YZ	PLoS52	performed the experiments|wrote the paper|reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
6270783	24886942	Ali Wang	2	participated in the discussions and supported manuscript corrections	participated in the discussions and supported manuscript corrections	Wrote the paper	Writing - Review & Editing	YES
6270783	24886942	Daowan Lai	2	reviewed manuscript and helped to revised it	reviewed manuscript and helped to revised it	Wrote the paper	Writing - Review & Editing	YES
6270783	24886942	Jiajia Meng	2	participated in the discussions and supported manuscript corrections	participated in the discussions and supported manuscript corrections	Wrote the paper	Writing - Review & Editing	YES
6270783	24886942	Jin Tian	2	participated in the discussions and supported manuscript corrections	participated in the discussions and supported manuscript corrections	Wrote the paper	Writing - Review & Editing	YES
6270783	24886942	Ligang Zhou	2	conceived the idea, designed review structure, supervised manuscript drafting, and revised manuscript	conceived the idea, designed review structure, supervised manuscript drafting, and revised manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
6270783	24886942	Shiqiong Lu	2	performed bibliographic researches, drafted and corrected manuscript	performed bibliographic researches, drafted and corrected manuscript	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
6270783	24886942	Weibo Sun	2	participated in the discussions and supported manuscript corrections	participated in the discussions and supported manuscript corrections	Wrote the paper	Writing - Review & Editing	YES
6270783	24886942	Xiaohan Wang	2	participated in the discussions and supported manuscript corrections	participated in the discussions and supported manuscript corrections	Wrote the paper	Writing - Review & Editing	YES
6270783	24886942	Xiaoxiang Fu	2	participated in the discussions and supported manuscript corrections	participated in the discussions and supported manuscript corrections	Wrote the paper	Writing - Review & Editing	YES
6270783	24886942	Yang Liu	2	conceived the idea, designed review structure, supervised manuscript drafting, and revised manuscript	conceived the idea, designed review structure, supervised manuscript drafting, and revised manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
5776780	29357813	CWH	2	performed the experiment	performed the experiment	Performed the experiments	Investigation	YES
5776780	29357813	GM	2	performed the experiment	performed the experiment	Performed the experiments	Investigation	YES
5776780	29357813	JDZ	2	performed the experiment|wrote the manuscript draft	performed the experiment	Performed the experiments	Investigation	YES
5776780	29357813	JDZ	2	performed the experiment|wrote the manuscript draft	wrote the manuscript draft	Wrote the paper	Writing - Original Draft	YES
5776780	29357813	JMB	2	conceived and designed the experiment	conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5776780	29357813	M Acevedo	2	conceived and designed the experiment|wrote the manuscript draft	conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5776780	29357813	M Acevedo	2	conceived and designed the experiment|wrote the manuscript draft	wrote the manuscript draft	Wrote the paper	Writing - Original Draft	YES
5776780	29357813	M Aoun	2	performed the experiment	performed the experiment	Performed the experiments	Investigation	YES
5776780	29357813	MNR	2	performed the experiment	performed the experiment	Performed the experiments	Investigation	YES
5776780	29357813	SC	2	performed the experiment	performed the experiment	Performed the experiments	Investigation	YES
5776780	29357813	ZAP	2	performed the experiment	performed the experiment	Performed the experiments	Investigation	YES
3491837	23027612	HS	2	contributed to the cholesterol efflux experiments	contributed to the cholesterol efflux experiments	Performed the experiments	Investigation	YES
3491837	23027612	SMS	2	contributed to the cholesterol efflux experiments	contributed to the cholesterol efflux experiments	Performed the experiments	Investigation	YES
1989134	17912352	HS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1989134	17912352	JM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1989134	17912352	KH	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1989134	17912352	KL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1989134	17912352	KL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1989134	17912352	KL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1989134	17912352	KL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1989134	17912352	KL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1989134	17912352	LV	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1989134	17912352	RW	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1989134	17912352	VR	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5124078	27872371	K.O.	2	provided critical intellectual input	provided critical intellectual input	-	-	NO
5124078	27872371	O.T.	2	provided critical intellectual input|provided critical intellectual input	provided critical intellectual input	-	-	NO
5124078	27872371	O.T.	2	provided critical intellectual input|provided critical intellectual input	provided critical intellectual input	-	-	NO
4418572	25938485	FCC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418572	25938485	FCC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418572	25938485	FCC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418572	25938485	FCC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418572	25938485	KCY	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418572	25938485	YQL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418572	25938485	YQL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418572	25938485	YQL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418572	25938485	YQL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6427946	30997005	A.G.	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
6427946	30997005	C.B.	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
6427946	30997005	C.K.	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
6427946	30997005	C.R.	2	contributed essential tools and technical expertise	contributed essential tools and technical expertise	Contributed reagents/materials/analysis tools	Resources	YES
6427946	30997005	H.K.	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
6427946	30997005	K.G.	2	wrote the manuscript|designed the study	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6427946	30997005	K.G.	2	wrote the manuscript|designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
6427946	30997005	L.B.	2	contributed essential tools and technical expertise	contributed essential tools and technical expertise	Contributed reagents/materials/analysis tools	Resources	YES
6427946	30997005	M.F.	2	contributed essential tools and technical expertise	contributed essential tools and technical expertise	Contributed reagents/materials/analysis tools	Resources	YES
6427946	30997005	N.S.	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6427946	30997005	O.T.	2	wrote the manuscript|designed the study	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6427946	30997005	O.T.	2	wrote the manuscript|designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
6427946	30997005	T.G.	2	wrote the manuscript|performed experiments|designed the study	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6427946	30997005	T.G.	2	wrote the manuscript|performed experiments|designed the study	performed experiments	Performed the experiments	Investigation	YES
6427946	30997005	T.G.	2	wrote the manuscript|performed experiments|designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
6427946	30997005	W.F.G.	2	contributed essential tools and technical expertise	contributed essential tools and technical expertise	Contributed reagents/materials/analysis tools	Resources	YES
3491838	22933245	AA	2	wrote the manuscript, which was approved by all authors|supervised the project and secured funding	wrote the manuscript, which was approved by all authors	Wrote the paper	Writing - Original Draft	YES
3491838	22933245	AA	2	wrote the manuscript, which was approved by all authors|supervised the project and secured funding	supervised the project and secured funding	-	Funding acquisition|Supervision	YES
3491838	22933245	AK	2	generated and analysed data for fig 6	generated and analysed data for fig 6	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3491838	22933245	AvW	2	generated and analysed data for fig 6	generated and analysed data for fig 6	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3491838	22933245	CJL	2	analysed data for all figures|wrote the manuscript, which was approved by all authors|supervised the project and secured funding	analysed data for all figures	Analyzed the data	Formal analysis|Visualization	YES
3491838	22933245	CJL	2	analysed data for all figures|wrote the manuscript, which was approved by all authors|supervised the project and secured funding	wrote the manuscript, which was approved by all authors	Wrote the paper	Writing - Original Draft	YES
3491838	22933245	CJL	2	analysed data for all figures|wrote the manuscript, which was approved by all authors|supervised the project and secured funding	supervised the project and secured funding	-	Funding acquisition|Supervision	YES
3491838	22933245	IB	2	generated and analysed data for all figures|wrote the manuscript, which was approved by all authors	generated and analysed data for all figures	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
3491838	22933245	IB	2	generated and analysed data for all figures|wrote the manuscript, which was approved by all authors	wrote the manuscript, which was approved by all authors	Wrote the paper	Writing - Original Draft	YES
3491838	22933245	JF	2	generated data for fig 1	generated data for fig 1	Performed the experiments	Investigation	YES
3491838	22933245	RB	2	generated data for fig 1	generated data for fig 1	Performed the experiments	Investigation	YES
6270784	25006793	All authors	2	contributed to and approved the final manuscript	contributed to and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6270784	25006793	E.B.	2	suggested the idea of the work and analysed the data	suggested the idea of the work and analysed the data	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
6270784	25006793	G.B.	2	performed experimental work and calculations	performed experimental work and calculations	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270784	25006793	S.S.	2	suggested the idea of the work and analysed the data|performed experimental work and calculations	suggested the idea of the work and analysed the data	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
6270784	25006793	S.S.	2	suggested the idea of the work and analysed the data|performed experimental work and calculations	performed experimental work and calculations	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5817628	29491876	AC	7	Provided field resources|Obtained funding	Provided field resources	Contributed reagents/materials/analysis tools	Resources	YES
5817628	29491876	AC	7	Provided field resources|Obtained funding	Obtained funding	-	Funding acquisition	YES
5817628	29491876	CS	7	Designed the experiments|Obtained funding|Wrote the manuscript	Designed the experiments	Conceived and designed the experiments	Methodology	YES
5817628	29491876	CS	7	Designed the experiments|Obtained funding|Wrote the manuscript	Obtained funding	-	Funding acquisition	YES
5817628	29491876	CS	7	Designed the experiments|Obtained funding|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5817628	29491876	JG	7	Curated and filtered the genotypic data and performed the ld analysis	Curated and filtered the genotypic data and performed the ld analysis	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5817628	29491876	KC	7	Designed the experiments|Provided field resources|Obtained funding	Designed the experiments	Conceived and designed the experiments	Methodology	YES
5817628	29491876	KC	7	Designed the experiments|Provided field resources|Obtained funding	Provided field resources	Contributed reagents/materials/analysis tools	Resources	YES
5817628	29491876	KC	7	Designed the experiments|Provided field resources|Obtained funding	Obtained funding	-	Funding acquisition	YES
5817628	29491876	MH	7	Calculated the phenotypic variation|Provided expert guidance on performing the gwas	Calculated the phenotypic variation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5817628	29491876	MH	7	Calculated the phenotypic variation|Provided expert guidance on performing the gwas	Provided expert guidance on performing the gwas	Performed the experiments	Investigation|Supervision	YES
5817628	29491876	SM	7	Designed the experiments|Conducted the experiments, analyzed the phenotypic data, performed the statistical analysis and gwas, and constructed the visualizations|Wrote the manuscript	Designed the experiments	Conceived and designed the experiments	Methodology	YES
5817628	29491876	SM	7	Designed the experiments|Conducted the experiments, analyzed the phenotypic data, performed the statistical analysis and gwas, and constructed the visualizations|Wrote the manuscript	Conducted the experiments, analyzed the phenotypic data, performed the statistical analysis and gwas, and constructed the visualizations	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
5817628	29491876	SM	7	Designed the experiments|Conducted the experiments, analyzed the phenotypic data, performed the statistical analysis and gwas, and constructed the visualizations|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5817628	29491876	ZZ	7	Provided expert guidance on performing the gwas|Obtained funding	Provided expert guidance on performing the gwas	Performed the experiments	Investigation|Supervision	YES
5817628	29491876	ZZ	7	Provided expert guidance on performing the gwas|Obtained funding	Obtained funding	-	Funding acquisition	YES
3493979	23027349	YG	2	contributed equally to this work	contributed equally to this work	-	-	NO
3493979	23027349	YP	2	contributed equally to this work	contributed equally to this work	-	-	NO
5834416	29500726	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5834416	29500726	Chemical Engineering	PLoS52	at lund university for providing the lignin-containing stream samples	at lund university for providing the lignin-containing stream samples	Contributed reagents/materials/analysis tools	Resources	YES
5834416	29500726	GL	PLoS52	conceived and designed the study|interpreted the experimental results|revised the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5834416	29500726	GL	PLoS52	conceived and designed the study|interpreted the experimental results|revised the manuscript	interpreted the experimental results	Analyzed the data	Formal analysis	YES
5834416	29500726	GL	PLoS52	conceived and designed the study|interpreted the experimental results|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5834416	29500726	JGH	PLoS52	conceived and designed the study|performed the experiments|interpreted the experimental results|drafted the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5834416	29500726	JGH	PLoS52	conceived and designed the study|performed the experiments|interpreted the experimental results|drafted the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5834416	29500726	JGH	PLoS52	conceived and designed the study|performed the experiments|interpreted the experimental results|drafted the manuscript	interpreted the experimental results	Analyzed the data	Formal analysis	YES
5834416	29500726	JGH	PLoS52	conceived and designed the study|performed the experiments|interpreted the experimental results|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5834416	29500726	KR	PLoS52	conceived and designed the study|performed the experiments|interpreted the experimental results|drafted the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5834416	29500726	KR	PLoS52	conceived and designed the study|performed the experiments|interpreted the experimental results|drafted the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5834416	29500726	KR	PLoS52	conceived and designed the study|performed the experiments|interpreted the experimental results|drafted the manuscript	interpreted the experimental results	Analyzed the data	Formal analysis	YES
5834416	29500726	KR	PLoS52	conceived and designed the study|performed the experiments|interpreted the experimental results|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5834416	29500726	MGG	PLoS52	conceived and designed the study|interpreted the experimental results|revised the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5834416	29500726	MGG	PLoS52	conceived and designed the study|interpreted the experimental results|revised the manuscript	interpreted the experimental results	Analyzed the data	Formal analysis	YES
5834416	29500726	MGG	PLoS52	conceived and designed the study|interpreted the experimental results|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5834416	29500726	MN	PLoS52	performed the experiments|interpreted the experimental results	performed the experiments	Performed the experiments	Investigation	YES
5834416	29500726	MN	PLoS52	performed the experiments|interpreted the experimental results	interpreted the experimental results	Analyzed the data	Formal analysis	YES
5834416	29500726	The authors	PLoS52	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
1989135	17912346	DS	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1989135	17912346	ND	PLoS5	Assisted in algorithm development	Assisted in algorithm development	Contributed reagents/materials/analysis tools	Software	YES
1989135	17912346	RE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1989135	17912346	RE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1989135	17912346	RE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1989135	17912346	RE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418573	25938517	AKE	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Final approval of manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4418573	25938517	AKE	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Final approval of manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418573	25938517	AKE	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Final approval of manuscript	Final approval of manuscript	-	-	NO
4418573	25938517	KG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Final approval of manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418573	25938517	KG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Final approval of manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4418573	25938517	KG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Final approval of manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418573	25938517	KG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Final approval of manuscript	Final approval of manuscript	-	-	NO
4418573	25938517	ME	PLoS5	Conceived and designed the experiments|Analyzed the data|Final approval of manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418573	25938517	ME	PLoS5	Conceived and designed the experiments|Analyzed the data|Final approval of manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4418573	25938517	ME	PLoS5	Conceived and designed the experiments|Analyzed the data|Final approval of manuscript	Final approval of manuscript	-	-	NO
4418573	25938517	MGH	PLoS5	Conceived and designed the experiments|Analyzed the data|Final approval of manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418573	25938517	MGH	PLoS5	Conceived and designed the experiments|Analyzed the data|Final approval of manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4418573	25938517	MGH	PLoS5	Conceived and designed the experiments|Analyzed the data|Final approval of manuscript	Final approval of manuscript	-	-	NO
4418573	25938517	MHNE	PLoS5	Conceived and designed the experiments|Analyzed the data|Final approval of manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418573	25938517	MHNE	PLoS5	Conceived and designed the experiments|Analyzed the data|Final approval of manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4418573	25938517	MHNE	PLoS5	Conceived and designed the experiments|Analyzed the data|Final approval of manuscript	Final approval of manuscript	-	-	NO
4418573	25938517	RN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418573	25938517	RN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418573	25938517	RN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418573	25938517	RN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418573	25938517	RN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5778671	29357812	BSC	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5778671	29357812	CHC	2	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5778671	29357812	DW	2	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5778671	29357812	HLZ	2	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5778671	29357812	JQH	2	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5778671	29357812	JYZ	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5778671	29357812	LTG	2	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5778671	29357812	QJW	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5778671	29357812	SLW	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5778671	29357812	WX	2	designed this research|carried out the experiments	designed this research	Conceived and designed the experiments	Methodology	YES
5778671	29357812	WX	2	designed this research|carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5778671	29357812	XGZ	2	designed this research|contributed the materials and reagents|revised the manuscript	designed this research	Conceived and designed the experiments	Methodology	YES
5778671	29357812	XGZ	2	designed this research|contributed the materials and reagents|revised the manuscript	contributed the materials and reagents	Contributed reagents/materials/analysis tools	Resources	YES
5778671	29357812	XGZ	2	designed this research|contributed the materials and reagents|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5778671	29357812	XY	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5778671	29357812	YJZ	2	designed this research|contributed the materials and reagents|revised the manuscript	designed this research	Conceived and designed the experiments	Methodology	YES
5778671	29357812	YJZ	2	designed this research|contributed the materials and reagents|revised the manuscript	contributed the materials and reagents	Contributed reagents/materials/analysis tools	Resources	YES
5778671	29357812	YJZ	2	designed this research|contributed the materials and reagents|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5778671	29357812	YNW	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5778671	29357812	ZZY	2	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
3491839	22933306	ACM	2	designed experiments, analyzed data and wrote the manuscript	designed experiments, analyzed data and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3491839	22933306	AGR	2	generated the three-dimensional images	generated the three-dimensional images	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
3491839	22933306	AH	2	supplied antibodies, designed experiments and discussed the results	supplied antibodies, designed experiments and discussed the results	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources	YES
3491839	22933306	All the authors	2	participated in the preparation of the manuscript	participated in the preparation of the manuscript	Wrote the paper	Writing - Original Draft	YES
3491839	22933306	CSF	2	samples and discussed the results	samples and discussed the results	-	-	NO
3491839	22933306	ES	2	provided human primary neuronal and mixed cultures	provided human primary neuronal and mixed cultures	Performed the experiments	Investigation	YES
3491839	22933306	JAC	2	generated data	generated data	Performed the experiments	Investigation	YES
5817962	29491871	All authors	2	revised the work and the manuscript critically|approved the final manuscript	revised the work and the manuscript critically	Wrote the paper	Writing - Review & Editing	YES
5817962	29491871	All authors	2	revised the work and the manuscript critically|approved the final manuscript	approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5817962	29491871	DL	2	performed the bioinformatics analyses of the toge project	performed the bioinformatics analyses of the toge project	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5817962	29491871	EM	2	planed the research and performed statistical analyses|designed the experiment of the toge project|wrote the manuscript with contributions from all authors	planed the research and performed statistical analyses	Analyzed the data	Formal analysis	YES
5817962	29491871	EM	2	planed the research and performed statistical analyses|designed the experiment of the toge project|wrote the manuscript with contributions from all authors	designed the experiment of the toge project	Conceived and designed the experiments	Methodology	YES
5817962	29491871	EM	2	planed the research and performed statistical analyses|designed the experiment of the toge project|wrote the manuscript with contributions from all authors	wrote the manuscript with contributions from all authors	Wrote the paper	Writing - Original Draft	YES
5817962	29491871	ES	2	performed statistical analyses	performed statistical analyses	Analyzed the data	Formal analysis	YES
5817962	29491871	GH	2	performed the experiment of the toge project	performed the experiment of the toge project	Performed the experiments	Investigation	YES
5817962	29491871	MB	2	designed the experiment of the toge project|advised on the analyses and interpretations of the results	designed the experiment of the toge project	Conceived and designed the experiments	Methodology	YES
5817962	29491871	MB	2	designed the experiment of the toge project|advised on the analyses and interpretations of the results	advised on the analyses and interpretations of the results	Analyzed the data	Formal analysis	YES
5817962	29491871	MZ	2	designed the experiment of the toge project|performed the bioinformatics analyses of the toge project	designed the experiment of the toge project	Conceived and designed the experiments	Methodology	YES
5817962	29491871	MZ	2	designed the experiment of the toge project|performed the bioinformatics analyses of the toge project	performed the bioinformatics analyses of the toge project	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5817962	29491871	PF	2	designed the experiment of the toge project|performed the experiment of the toge project	designed the experiment of the toge project	Conceived and designed the experiments	Methodology	YES
5817962	29491871	PF	2	designed the experiment of the toge project|performed the experiment of the toge project	performed the experiment of the toge project	Performed the experiments	Investigation	YES
5817962	29491871	SL	2	planed the research and performed statistical analyses	planed the research and performed statistical analyses	Analyzed the data	Formal analysis	YES
5817962	29491871	VLB-A	2	advised on the analyses and interpretations of the results	advised on the analyses and interpretations of the results	Analyzed the data	Formal analysis	YES
6270786	25365298	AGW	2	designed the study, analyzed the results and wrote the manuscript	designed the study, analyzed the results and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
6270786	25365298	AVA	2	designed the study, analyzed the results and wrote the manuscript	designed the study, analyzed the results and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
6270786	25365298	CFBV	2	performed the animal experiments	performed the animal experiments	Performed the experiments	Investigation	YES
6270786	25365298	HMLM	2	performed the animal experiments	performed the animal experiments	Performed the experiments	Investigation	YES
6270786	25365298	JCSN	2	performed the histopathological and immunohistochemical analysis	performed the histopathological and immunohistochemical analysis	Performed the experiments	Investigation	YES
6270786	25365298	JHCS	2	designed the study, analyzed the results and wrote the manuscript	designed the study, analyzed the results and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
6270786	25365298	LAR	2	performed and analyzed the chromatography	performed and analyzed the chromatography	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270786	25365298	MPF	2	performed and analyzed the biochemical studies	performed and analyzed the biochemical studies	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270786	25365298	PJRN	2	performed and analyzed the chromatography	performed and analyzed the chromatography	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270786	25365298	RCSF	2	performed and analyzed the biochemical studies	performed and analyzed the biochemical studies	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4418574	25938836	FN	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418574	25938836	FN	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418574	25938836	FN	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418574	25938836	KK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418574	25938836	KK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418574	25938836	KK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418574	25938836	KK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418574	25938836	KK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418574	25938836	MJB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418574	25938836	MJB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418574	25938836	MJB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418574	25938836	MJB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418574	25938836	MJB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418574	25938836	TEH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418574	25938836	TEH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418574	25938836	TEH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418574	25938836	TEH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418574	25938836	TEH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1989136	17912345	BJ	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1989136	17912345	BJ	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1989136	17912345	CK	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1989136	17912345	CK	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1989136	17912345	CK	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1989136	17912345	IL	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1989136	17912345	IL	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1989136	17912345	JG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1989136	17912345	JG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1989136	17912345	JG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1989136	17912345	KG	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1989136	17912345	KG	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1989136	17912345	PS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1989136	17912345	PS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1989136	17912345	RL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1989136	17912345	RL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1989136	17912345	RL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1989136	17912345	TJ	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1989136	17912345	TJ	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1989136	17912345	TP	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1989136	17912345	TP	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1989136	17912345	WL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1989136	17912345	WL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1989136	17912345	WL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1989136	17912345	WL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1989136	17912345	WL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5838027	29508097	AGS	2	participated in the design of the study and its coordination, carried out molecular genetic engineering and strain constructions	participated in the design of the study and its coordination, carried out molecular genetic engineering and strain constructions	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Project administration	YES
5838027	29508097	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5838027	29508097	DPN	2	carried out growth assays, hplc analysis and drafted the manuscript	carried out growth assays, hplc analysis and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5838027	29508097	GL	2	conceived the study, participated in the design of the study and its coordination and helped to draft the manuscript	conceived the study, participated in the design of the study and its coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
5838027	29508097	HA	2	carried out bioreactor experiments	carried out bioreactor experiments	Performed the experiments	Investigation	YES
5838027	29508097	LW	2	participated in the design of the study and its coordination, carried out molecular genetic engineering and strain constructions|carried out growth assays, hplc analysis and drafted the manuscript	participated in the design of the study and its coordination, carried out molecular genetic engineering and strain constructions	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Project administration	YES
5838027	29508097	LW	2	participated in the design of the study and its coordination, carried out molecular genetic engineering and strain constructions|carried out growth assays, hplc analysis and drafted the manuscript	carried out growth assays, hplc analysis and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5838027	29508097	MGG	2	conceived the study, participated in the design of the study and its coordination and helped to draft the manuscript	conceived the study, participated in the design of the study and its coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
5838027	29508097	UPLC	2	hplc analysis	hplc analysis	Performed the experiments	Investigation	YES
5182413	27994122	A.A.	2	designed research|supervised the work|discussed the results and commented on the paper	designed research	Conceived and designed the experiments	Methodology	YES
5182413	27994122	A.A.	2	designed research|supervised the work|discussed the results and commented on the paper	supervised the work	-	Supervision	YES
5182413	27994122	A.A.	2	designed research|supervised the work|discussed the results and commented on the paper	discussed the results and commented on the paper	-	-	NO
5182413	27994122	All authors	2	discussed the results and commented on the paper	discussed the results and commented on the paper	-	-	NO
5182413	27994122	H.F.J.	2	designed research|arranged the bird skeletal specimens|discussed the results and commented on the paper	designed research	Conceived and designed the experiments	Methodology	YES
5182413	27994122	H.F.J.	2	designed research|arranged the bird skeletal specimens|discussed the results and commented on the paper	arranged the bird skeletal specimens	Performed the experiments	Investigation	YES
5182413	27994122	H.F.J.	2	designed research|arranged the bird skeletal specimens|discussed the results and commented on the paper	discussed the results and commented on the paper	-	-	NO
5182413	27994122	M.T.	2	designed research|arranged the bird skeletal specimens|collected data|analysed data	designed research	Conceived and designed the experiments	Methodology	YES
5182413	27994122	M.T.	2	designed research|arranged the bird skeletal specimens|collected data|analysed data	arranged the bird skeletal specimens	Performed the experiments	Investigation	YES
5182413	27994122	M.T.	2	designed research|arranged the bird skeletal specimens|collected data|analysed data	collected data	Performed the experiments	Investigation	YES
5182413	27994122	M.T.	2	designed research|arranged the bird skeletal specimens|collected data|analysed data	analysed data	Analyzed the data	Formal analysis	YES
5182413	27994122	W.Y.	2	analysed data|discussed the results and commented on the paper	analysed data	Analyzed the data	Formal analysis	YES
5182413	27994122	W.Y.	2	analysed data|discussed the results and commented on the paper	discussed the results and commented on the paper	-	-	NO
3493981	23027351	All authors	2	were involved in critically revising the manuscript for important intellectual content and approved the final version	were involved in critically revising the manuscript for important intellectual content and approved the final version	Wrote the paper	Writing - Review & Editing	YES
3493981	23027351	GS	2	critical manuscript revision, article drafting	critical manuscript revision, article drafting	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3493981	23027351	HL	2	research design, manuscript writing, data acquisition and analysis, revising and final approval	research design, manuscript writing, data acquisition and analysis, revising and final approval	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3493981	23027351	HW	2	research performing, data analysis	research performing, data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3493981	23027351	WL	2	research performing, data analysis	research performing, data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5778672	29357827	BH	2	designed the experiment and wrote the manuscript	designed the experiment and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5778672	29357827	YX	2	designed the experiment and wrote the manuscript|conducted the experiment and data analysis	designed the experiment and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5778672	29357827	YX	2	designed the experiment and wrote the manuscript|conducted the experiment and data analysis	conducted the experiment and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5818394	29497438	HjL	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
5818394	29497438	HjL	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5818394	29497438	HpZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents, materials, analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5818394	29497438	HpZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents, materials, analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5818394	29497438	HpZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents, materials, analysis tools|Wrote the paper	Contributed reagents, materials, analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5818394	29497438	HpZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents, materials, analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5818394	29497438	HxZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents, materials, analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5818394	29497438	HxZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents, materials, analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5818394	29497438	HxZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents, materials, analysis tools|Wrote the paper	Contributed reagents, materials, analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5818394	29497438	HxZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents, materials, analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5818394	29497438	HyL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5818394	29497438	JL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5818394	29497438	JZ	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5818394	29497438	LX	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5818394	29497438	LY	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5818394	29497438	PC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5818394	29497438	PC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
5818394	29497438	PC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5818394	29497438	PC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5818394	29497438	SH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents, materials, analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5818394	29497438	SH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents, materials, analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5818394	29497438	SH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents, materials, analysis tools|Wrote the paper	Contributed reagents, materials, analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5818394	29497438	SH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents, materials, analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5818394	29497438	YW	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
3491840	23027613	EF	2	helped with real time pcr and elisa	helped with real time pcr and elisa	Performed the experiments	Investigation	YES
3491840	23027613	G-PS	2	designed the experiments, participated in all data analyses and prepared the manuscript	designed the experiments, participated in all data analyses and prepared the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3491840	23027613	HC	2	induced mouse obesity and diabetes, monitored body weight, performed insulin tolerance and glucose tolerance assays and completed facs analyses	induced mouse obesity and diabetes, monitored body weight, performed insulin tolerance and glucose tolerance assays and completed facs analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Supervision	YES
3491840	23027613	JW	2	induced mouse obesity and diabetes, monitored body weight, performed insulin tolerance and glucose tolerance assays and completed facs analyses	induced mouse obesity and diabetes, monitored body weight, performed insulin tolerance and glucose tolerance assays and completed facs analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Supervision	YES
3491840	23027613	PL	2	assisted with the data interpretation and manuscript writing	assisted with the data interpretation and manuscript writing	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3491840	23027613	SS	2	performed vat immunohistochemistry	performed vat immunohistochemistry	Performed the experiments	Investigation	YES
3491840	23027613	WK	2	induced mouse obesity and diabetes, monitored body weight, performed insulin tolerance and glucose tolerance assays and completed facs analyses	induced mouse obesity and diabetes, monitored body weight, performed insulin tolerance and glucose tolerance assays and completed facs analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Supervision	YES
3491840	23027613	XC	2	induced mouse obesity and diabetes, monitored body weight, performed insulin tolerance and glucose tolerance assays and completed facs analyses|designed the experiments, participated in all data analyses and prepared the manuscript	induced mouse obesity and diabetes, monitored body weight, performed insulin tolerance and glucose tolerance assays and completed facs analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Supervision	YES
3491840	23027613	XC	2	induced mouse obesity and diabetes, monitored body weight, performed insulin tolerance and glucose tolerance assays and completed facs analyses|designed the experiments, participated in all data analyses and prepared the manuscript	designed the experiments, participated in all data analyses and prepared the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3491840	23027613	YHL	2	helped with data explanation and manuscript writing	helped with data explanation and manuscript writing	Wrote the paper	Writing - Original Draft	YES
6270787	24786691	Ali Fan Administration	2	collection of wogonin biosamples	collection of wogonin biosamples	Performed the experiments	Investigation	YES
6270787	24786691	Amer Talbi Coordination	2	execution of research protocol	execution of research protocol	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6270787	24786691	Junxiu Li Chromatographic	2	analysis of plasma samples	analysis of plasma samples	Performed the experiments	Investigation	YES
6270787	24786691	Qingwang Liu Chromatographic	2	process design and quality control for quantification of wogonin	process design and quality control for quantification of wogonin	Conceived and designed the experiments|Performed the experiments	Validation	YES
6270787	24786691	Xijing Chen General	2	design of the research protocol, analysis of pharmacokinetic behavior of wogonin	design of the research protocol, analysis of pharmacokinetic behavior of wogonin	Conceived and designed the experiments	Methodology	YES
6270787	24786691	Zhao Di Coordination	2	execution of research protocol	execution of research protocol	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4418575	25938575	AM	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418575	25938575	KF	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418575	25938575	M. Kolecka	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418575	25938575	M. Kolecka	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418575	25938575	M. Kramer	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418575	25938575	MJS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418575	25938575	MJS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418575	25938575	MJS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418575	25938575	MJS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418575	25938575	NO	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418575	25938575	NO	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418575	25938575	NO	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418575	25938575	SL	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4418575	25938575	SL	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1989137	17912347	AT	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1989137	17912347	AT	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1989137	17912347	AT	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1989137	17912347	JK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1989137	17912347	JK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1989137	17912347	NA	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1989137	17912347	NA	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1989137	17912347	SE	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1989137	17912347	SR	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1989137	17912347	VS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1989137	17912347	VS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5778740	29357833	AFM	1	Concept and study design|Data acquisition and analysis	Concept and study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5778740	29357833	AFM	1	Concept and study design|Data acquisition and analysis	Data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5778740	29357833	DRN	1	Concept and study design|Data acquisition and analysis|Drafting the manuscript and figures	Concept and study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5778740	29357833	DRN	1	Concept and study design|Data acquisition and analysis|Drafting the manuscript and figures	Data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5778740	29357833	DRN	1	Concept and study design|Data acquisition and analysis|Drafting the manuscript and figures	Drafting the manuscript and figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5778740	29357833	GWM	1	Concept and study design|Data acquisition and analysis	Concept and study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5778740	29357833	GWM	1	Concept and study design|Data acquisition and analysis	Data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5778740	29357833	ZFG	1	Concept and study design|Data acquisition and analysis|Drafting the manuscript and figures	Concept and study design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5778740	29357833	ZFG	1	Concept and study design|Data acquisition and analysis|Drafting the manuscript and figures	Data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5778740	29357833	ZFG	1	Concept and study design|Data acquisition and analysis|Drafting the manuscript and figures	Drafting the manuscript and figures	Wrote the paper	Visualization|Writing - Original Draft	YES
4418576	25938446	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418576	25938446	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418576	25938446	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418576	25938446	PHZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418576	25938446	PHZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418576	25938446	PHZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418576	25938446	PHZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5818415	29497430	AK	2	also contributed to critical reading	also contributed to critical reading	-	-	NO
5818415	29497430	DR	2	designed the experiments|contributed to the interpretation of results and writing of the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5818415	29497430	DR	2	designed the experiments|contributed to the interpretation of results and writing of the manuscript	contributed to the interpretation of results and writing of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5818415	29497430	EB	2	designed the experiments|performed the ril population development and the rust evaluations|carried out the qtl analysis and wrote most of the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5818415	29497430	EB	2	designed the experiments|performed the ril population development and the rust evaluations|carried out the qtl analysis and wrote most of the manuscript	performed the ril population development and the rust evaluations	Performed the experiments	Investigation	YES
5818415	29497430	EB	2	designed the experiments|performed the ril population development and the rust evaluations|carried out the qtl analysis and wrote most of the manuscript	carried out the qtl analysis and wrote most of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5818415	29497430	EC	2	performed the snps analysis in the ril population and critically reviewed the manuscript	performed the snps analysis in the ril population and critically reviewed the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5818415	29497430	JC	2	also contributed to critical reading	also contributed to critical reading	-	-	NO
5818415	29497430	MC	2	carried out the qtl analysis and wrote most of the manuscript	carried out the qtl analysis and wrote most of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5818415	29497430	STSs	2	evaluation in the ril population	evaluation in the ril population	-	-	NO
5842170	29516233	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5842170	29516233	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
6270788	24962392	A. Lipeeva	2	performed synthesis, identification, and structure elucidation of the compounds, and prepared the manuscript	performed synthesis, identification, and structure elucidation of the compounds, and prepared the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6270788	24962392	E. Shults	2	the corresponding author	the corresponding author	-	-	NO
6270788	24962392	G. Pokrovsky	2	contributed to the cytotoxicity experiments	contributed to the cytotoxicity experiments	Performed the experiments	Investigation	YES
6270788	24962392	M. Shakirov	2	contributed to checking and confirming the procedures of the structural identification, especially interpretation of the nmr spectra	contributed to checking and confirming the procedures of the structural identification, especially interpretation of the nmr spectra	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3491841	23027614	All the authors	PLoS52	put their comments for editing the manuscript	put their comments for editing the manuscript	Wrote the paper	Writing - Review & Editing	YES
3491841	23027614	BM	PLoS52	performed and analysed cytokine profile	performed and analysed cytokine profile	Performed the experiments	Investigation	YES
3491841	23027614	HKM	PLoS52	overall supervised the project|wrote the paper	overall supervised the project	-	Supervision	YES
3491841	23027614	HKM	PLoS52	overall supervised the project|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3491841	23027614	PJ	PLoS52	did the isolation of niranthin from the plant and chemically analyse the compound	did the isolation of niranthin from the plant and chemically analyse the compound	Performed the experiments	Investigation	YES
3491841	23027614	RM	PLoS52	helped sac for performing in vivo animal infection and analysis of statistical significance	helped sac for performing in vivo animal infection and analysis of statistical significance	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3491841	23027614	SR	PLoS52	provided intellectual input for in vivo studies	provided intellectual input for in vivo studies	Performed the experiments	Investigation	YES
3491841	23027614	SS	PLoS52	helped in performing fluorescence quenching experiments	helped in performing fluorescence quenching experiments	Performed the experiments	Investigation	YES
3491841	23027614	SaC	PLoS52	designed, performed and analysed the topoisomerase related experiments|performed and analysed cytokine profile|wrote the paper	designed, performed and analysed the topoisomerase related experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3491841	23027614	SaC	PLoS52	designed, performed and analysed the topoisomerase related experiments|performed and analysed cytokine profile|wrote the paper	performed and analysed cytokine profile	Performed the experiments	Investigation	YES
3491841	23027614	SaC	PLoS52	designed, performed and analysed the topoisomerase related experiments|performed and analysed cytokine profile|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3491841	23027614	ShC	PLoS52	did the isolation of niranthin from the plant and chemically analyse the compound	did the isolation of niranthin from the plant and chemically analyse the compound	Performed the experiments	Investigation	YES
3491841	23027614	TM	PLoS52	did the isolation of niranthin from the plant and chemically analyse the compound|wrote the paper	did the isolation of niranthin from the plant and chemically analyse the compound	Performed the experiments	Investigation	YES
3491841	23027614	TM	PLoS52	did the isolation of niranthin from the plant and chemically analyse the compound|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
1989138	17912357	CG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1989138	17912357	CG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1989138	17912357	CG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1989138	17912357	CG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1989138	17912357	DT	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1989138	17912357	DT	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1989138	17912357	DT	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1989138	17912357	DT	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1989138	17912357	FR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1989138	17912357	FR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1989138	17912357	FR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1989138	17912357	FR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418577	25938670	AKA	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418577	25938670	AKA	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418577	25938670	AKA	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418577	25938670	DB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418577	25938670	DB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418577	25938670	DB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418577	25938670	SP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418577	25938670	SP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418577	25938670	SP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3493983	23027353	AML	2	research theme defining, methods designing, results analysis and interpretation and manuscript writing	research theme defining, methods designing, results analysis and interpretation and manuscript writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3493983	23027353	DC	2	laboratory experiments performing	laboratory experiments performing	Performed the experiments	Investigation	YES
3493983	23027353	FF	2	laboratory experiments performing	laboratory experiments performing	Performed the experiments	Investigation	YES
3493983	23027353	IT	2	laboratory experiments performing	laboratory experiments performing	Performed the experiments	Investigation	YES
3493983	23027353	SM	2	research theme defining, methods designing, results analysis and interpretation and manuscript writing	research theme defining, methods designing, results analysis and interpretation and manuscript writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3493983	23027353	VL	2	research theme defining, methods designing, results analysis and interpretation and manuscript writing|laboratory experiments performing	research theme defining, methods designing, results analysis and interpretation and manuscript writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3493983	23027353	VL	2	research theme defining, methods designing, results analysis and interpretation and manuscript writing|laboratory experiments performing	laboratory experiments performing	Performed the experiments	Investigation	YES
5182420	27994129	A.H.	2	performed molecular experiments including mutation scanning by sequencing to confirm the mutation, and provided comments on the manuscript	performed molecular experiments including mutation scanning by sequencing to confirm the mutation, and provided comments on the manuscript	Performed the experiments	Investigation	YES
5182420	27994129	B.W.D.	2	collated and aligned whole genome sequences	collated and aligned whole genome sequences	Performed the experiments	Investigation	YES
5182420	27994129	D.L.D.	2	traced the pedigree of the aht breed and mutation, prepared the associated figure and contributed to the text and editing of the paper	traced the pedigree of the aht breed and mutation, prepared the associated figure and contributed to the text and editing of the paper	Wrote the paper	Visualization|Writing - Original Draft|Writing - Review & Editing	YES
5182420	27994129	E.A.O.	2	wrote the initial drafts of the paper, oversaw the development of figures and provided final edits	wrote the initial drafts of the paper, oversaw the development of figures and provided final edits	Wrote the paper	Supervision|Visualization|Writing - Original Draft|Writing - Review & Editing	YES
5182420	27994129	H.G.P.	2	carried out experiments leading to the discovery of hairless mutations in the aht and contributed in writing the paper and preparing figures	carried out experiments leading to the discovery of hairless mutations in the aht and contributed in writing the paper and preparing figures	Performed the experiments|Wrote the paper	Investigation|Visualization|Writing - Original Draft	YES
5818416	29497437	CZ	7	Helped completing the manuscript	Helped completing the manuscript	-	-	NO
5818416	29497437	HD	7	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5818416	29497437	JX	7	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5818416	29497437	LZ	7	Performed the experiments and collected the data	Performed the experiments and collected the data	Performed the experiments	Investigation	YES
5818416	29497437	MW	7	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5818416	29497437	MY	7	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5818416	29497437	TL	7	Performed the experiments and collected the data	Performed the experiments and collected the data	Performed the experiments	Investigation	YES
5818416	29497437	YC	7	Performed the experiments and collected the data	Performed the experiments and collected the data	Performed the experiments	Investigation	YES
5818416	29497437	YFC	7	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5818416	29497437	YG	7	Conducted field work	Conducted field work	Performed the experiments	Investigation	YES
4418578	25938464	DC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418578	25938464	DC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418578	25938464	DC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418578	25938464	DC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418578	25938464	KD	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418578	25938464	KD	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418578	25938464	MM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418578	25938464	MM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418578	25938464	MM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1989139	17912348	AC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1989139	17912348	AC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1989139	17912348	CK	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1989139	17912348	DB	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1989139	17912348	DT	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1989139	17912348	DT	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1989139	17912348	DT	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1989139	17912348	EC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1989139	17912348	EC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1989139	17912348	EC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1989139	17912348	EL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1989139	17912348	FM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1989139	17912348	FM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1989139	17912348	FV	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1989139	17912348	GA	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1989139	17912348	JG	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1989139	17912348	LK	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1989139	17912348	LK	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1989139	17912348	LK	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1989139	17912348	LP	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1989139	17912348	LP	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1989139	17912348	MB	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1989139	17912348	MB	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1989139	17912348	MC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Designed the study|Wrote the first draft of the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1989139	17912348	MC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Designed the study|Wrote the first draft of the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1989139	17912348	MC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Designed the study|Wrote the first draft of the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1989139	17912348	MC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Designed the study|Wrote the first draft of the paper	Designed the study	Conceived and designed the experiments	Methodology	YES
1989139	17912348	MC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Designed the study|Wrote the first draft of the paper	Wrote the first draft of the paper	Wrote the paper	Writing - Original Draft	YES
1989139	17912348	MN	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1989139	17912348	MN	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1989139	17912348	MN	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1989139	17912348	MS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1989139	17912348	SL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
3891239	24459422	Hongyan Chen	2	contributed to the work equally and should be regarded as co-first authors	contributed to the work equally and should be regarded as co-first authors	-	-	NO
3891239	24459422	Qing Miao	2	contributed to the work equally and should be regarded as co-first authors	contributed to the work equally and should be regarded as co-first authors	-	-	NO
3493984	23027354	All authors	2	evaluated micrographs, critically revised the manuscript and approved the final version of this article	evaluated micrographs, critically revised the manuscript and approved the final version of this article	Wrote the paper	Writing - Review & Editing	YES
3493984	23027354	GM	2	study designed and direction|contribution to morphological studies	study designed and direction	Conceived and designed the experiments	Methodology	YES
3493984	23027354	GM	2	study designed and direction|contribution to morphological studies	contribution to morphological studies	Performed the experiments	Investigation	YES
3493984	23027354	MAK	2	literature review, manuscript writing	literature review, manuscript writing	Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
3493984	23027354	MGP	2	contribution to morphological studies	contribution to morphological studies	Performed the experiments	Investigation	YES
3493984	23027354	MM	2	contribution to morphological studies	contribution to morphological studies	Performed the experiments	Investigation	YES
3493984	23027354	SAN	2	study designed and direction|contribution to morphological studies	study designed and direction	Conceived and designed the experiments	Methodology	YES
3493984	23027354	SAN	2	study designed and direction|contribution to morphological studies	contribution to morphological studies	Performed the experiments	Investigation	YES
3493984	23027354	SB	2	contribution to morphological studies	contribution to morphological studies	Performed the experiments	Investigation	YES
6270790	25525822	C. Alvarado-Castillo	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6270790	25525822	C. Alvarado-Castillo	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
6270790	25525822	C. Alvarado-Castillo	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
6270790	25525822	C. Alvarado-Castillo	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270790	25525822	E. Lucena	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
6270790	25525822	G. Acha	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
6270790	25525822	O. Estrada	PLoS52	performed the experiments|analyzed the data|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
6270790	25525822	O. Estrada	PLoS52	performed the experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
6270790	25525822	O. Estrada	PLoS52	performed the experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270790	25525822	W. Contreras	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
6270790	25525822	W. Contreras	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
6270790	25525822	W. Venturini	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5780744	29363429	NO	2	designed and performed the research	designed and performed the research	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5845091	29523988	All authors	2	read and approved the final manuscript|thank their universities for their help in accomplishing this work	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5845091	29523988	All authors	2	read and approved the final manuscript|thank their universities for their help in accomplishing this work	thank their universities for their help in accomplishing this work	-	-	NO
5845091	29523988	FA	2	helped in the analysis	helped in the analysis	-	-	NO
5845091	29523988	IHRA	2	main performer of this study|wrote the article	main performer of this study	Performed the experiments	Investigation	YES
5845091	29523988	IHRA	2	main performer of this study|wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
5845091	29523988	JHY	2	conceived the idea of the study, reviewed and approved the final manuscript	conceived the idea of the study, reviewed and approved the final manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5845091	29523988	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5845091	29523988	YCC	2	conceived the idea of the study, reviewed and approved the final manuscript|wrote the article	conceived the idea of the study, reviewed and approved the final manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5845091	29523988	YCC	2	conceived the idea of the study, reviewed and approved the final manuscript|wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
5818428	29497428	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4641165	26605328	Bao Zhang	2	contributed equally to this work	contributed equally to this work	-	-	NO
4641165	26605328	Qian Rui Fan	2	contributed equally to this work	contributed equally to this work	-	-	NO
1989140	17912358	FS	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1989140	17912358	KS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1989140	17912358	KS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1989140	17912358	PW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1989140	17912358	PW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1989140	17912358	PW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1989140	17912358	PW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1989140	17912358	SE	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1989140	17912358	SE	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1989140	17912358	SE	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1989140	17912358	UH	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1989140	17912358	UH	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
3494873	23070965	ABa	2	performed the immunostaining of mouse tissues and contributed to the preparation of the figures	performed the immunostaining of mouse tissues and contributed to the preparation of the figures	Performed the experiments	Investigation|Visualization	YES
3494873	23070965	ABu	2	performed the spr analyses and contributed to the revision of the manuscript	performed the spr analyses and contributed to the revision of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
3494873	23070965	AM	2	managed the collection of human samples and performed the analysis of clinical data	managed the collection of human samples and performed the analysis of clinical data	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
3494873	23070965	DR	2	performed in vivo experiments	performed in vivo experiments	Performed the experiments	Investigation	YES
3494873	23070965	FB	2	contributed to the preparation of the manuscript and provided research founding	contributed to the preparation of the manuscript and provided research founding	Wrote the paper	Writing - Original Draft	YES
3494873	23070965	JS	2	performed the bioinformatics analyses	performed the bioinformatics analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3494873	23070965	LC	2	supported the collection of human samples and provided a critical evaluation of the manuscript	supported the collection of human samples and provided a critical evaluation of the manuscript	Performed the experiments	Investigation	YES
3494873	23070965	MM	2	performed the proteomics analyses	performed the proteomics analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3494873	23070965	MR	2	performed the spr analyses and contributed to the revision of the manuscript	performed the spr analyses and contributed to the revision of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
3494873	23070965	MS	2	performed in vivo experiments and contributed to the preparation of the figures	performed in vivo experiments and contributed to the preparation of the figures	Performed the experiments	Investigation|Visualization	YES
3494873	23070965	PB	2	performed in vitro experiments	performed in vitro experiments	Performed the experiments	Investigation	YES
3494873	23070965	PC	2	managed the collection of human samples	managed the collection of human samples	Performed the experiments	Investigation	YES
3494873	23070965	PP	2	supported the proteomics analyses and provided research founding	supported the proteomics analyses and provided research founding	Analyzed the data	Formal analysis	YES
3494873	23070965	RG	2	supported the set up of the hccm-1544 model	supported the set up of the hccm-1544 model	Performed the experiments	Methodology	YES
3494873	23070965	RP	2	coordinated the phage display and bioinformatics approaches, contributed to the preparation of the manuscript, and provided research founding	coordinated the phage display and bioinformatics approaches, contributed to the preparation of the manuscript, and provided research founding	Wrote the paper	Formal analysis|Project administration|Writing - Original Draft	YES
3494873	23070965	SA	2	managed the collection of human samples	managed the collection of human samples	Performed the experiments	Investigation	YES
3494873	23070965	SC	2	performed in vivo experiments	performed in vivo experiments	Performed the experiments	Investigation	YES
3494873	23070965	SM	2	conceived the project, performed the phage display biopanning and part of the in vitro experiments, wrote the manuscript, prepared the figures, and provided research founding	conceived the project, performed the phage display biopanning and part of the in vitro experiments, wrote the manuscript, prepared the figures, and provided research founding	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Visualization|Writing - Original Draft	YES
3494873	23070965	VB	2	performed in vivo and in vitro experiments	performed in vivo and in vitro experiments	Performed the experiments	Investigation	YES
3494873	23070965	WA	2	coordinated the phage display and bioinformatics approaches, contributed to the preparation of the manuscript, and provided research founding	coordinated the phage display and bioinformatics approaches, contributed to the preparation of the manuscript, and provided research founding	Wrote the paper	Formal analysis|Project administration|Writing - Original Draft	YES
6270791	25197931	All authors	2	wrote portions of this review	wrote portions of this review	Wrote the paper	Writing - Original Draft	YES
4449379	25471465	BO	2	critically reviewed and edited the manuscript and involved participants interview results writing	critically reviewed and edited the manuscript and involved participants interview results writing	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
4449379	25471465	BP	2	led program design, training, and data analysis|carried out manuscript writing	led program design, training, and data analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis	YES
4449379	25471465	BP	2	led program design, training, and data analysis|carried out manuscript writing	carried out manuscript writing	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4449379	25471465	LZ	2	coordinated program implementation and participated in data collection	coordinated program implementation and participated in data collection	Performed the experiments	Investigation|Project administration	YES
4449379	25471465	XZ	2	led the program implementation and coordinated data collection|carried out manuscript writing	led the program implementation and coordinated data collection	Performed the experiments	Investigation|Project administration	YES
4449379	25471465	XZ	2	led the program implementation and coordinated data collection|carried out manuscript writing	carried out manuscript writing	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4418579	25938512	AR	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418579	25938512	ARK	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418579	25938512	CTL	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418579	25938512	CTL	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418579	25938512	HT	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418579	25938512	KF	PLoS5	Contributed reagents/materials/analysis tools|Designed the software used in analysis	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418579	25938512	KF	PLoS5	Contributed reagents/materials/analysis tools|Designed the software used in analysis	Designed the software used in analysis	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
4418579	25938512	KN	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418579	25938512	NM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418579	25938512	NT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the software used in analysis	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418579	25938512	NT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the software used in analysis	Performed the experiments	Performed the experiments	Investigation	YES
4418579	25938512	NT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the software used in analysis	Analyzed the data	Analyzed the data	Formal analysis	YES
4418579	25938512	NT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the software used in analysis	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418579	25938512	NT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the software used in analysis	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418579	25938512	NT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the software used in analysis	Designed the software used in analysis	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
4418579	25938512	SLL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4418579	25938512	SLL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418579	25938512	TK	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418579	25938512	TO	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418579	25938512	TO	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418579	25938512	TY	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418579	25938512	Y. Taguchi	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4418579	25938512	Y. Taguchi	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418579	25938512	Y. Tsumura	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418579	25938512	Y. Tsumura	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
3567759	23361236	AL	2	design and analysis of data	design and analysis of data	Conceived and designed the experiments|Analyzed the data	Formal analysis	YES
3567759	23361236	CG	2	design and interpretation of data	design and interpretation of data	Conceived and designed the experiments|Analyzed the data	Formal analysis	YES
3567759	23361236	DF	2	conception, design, data interpretation	conception, design, data interpretation	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
3567759	23361236	GF	2	critical revision of the manuscript	critical revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
3567759	23361236	GM	2	preparation and manuscript critical revision	preparation and manuscript critical revision	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3567759	23361236	NI	2	preparation and manuscript critical revision	preparation and manuscript critical revision	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3567759	23361236	PVE	2	preparation and manuscript critical revision	preparation and manuscript critical revision	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3567759	23361236	SM	2	manuscript preparation	manuscript preparation	Wrote the paper	Writing - Original Draft	YES
3567759	23361236	SN	2	design and analysis of data	design and analysis of data	Conceived and designed the experiments|Analyzed the data	Formal analysis	YES
3567759	23361236	VF	2	critical revision of the manuscript	critical revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5818429	29497429	CL	2	performed the experiments and carried out the analysis|wrote the manuscript	performed the experiments and carried out the analysis	Performed the experiments	Investigation	YES
5818429	29497429	CL	2	performed the experiments and carried out the analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5818429	29497429	JW	2	performed the experiments and carried out the analysis	performed the experiments and carried out the analysis	Performed the experiments	Investigation	YES
5818429	29497429	MZ	2	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5818429	29497429	XL	2	designed the experiments|performed the experiments and carried out the analysis|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5818429	29497429	XL	2	designed the experiments|performed the experiments and carried out the analysis|wrote the manuscript	performed the experiments and carried out the analysis	Performed the experiments	Investigation	YES
5818429	29497429	XL	2	designed the experiments|performed the experiments and carried out the analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5818429	29497429	XM	2	performed the experiments and carried out the analysis	performed the experiments and carried out the analysis	Performed the experiments	Investigation	YES
5818429	29497429	YT	2	performed the experiments and carried out the analysis	performed the experiments and carried out the analysis	Performed the experiments	Investigation	YES
5847638	29532188	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5847638	29532188	DP	2	supervised the project|analyzed the data and wrote the manuscript	supervised the project	-	Supervision	YES
5847638	29532188	DP	2	supervised the project|analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5847638	29532188	JB	2	conceived the study|designed and performed the experiments|analyzed the data and wrote the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5847638	29532188	JB	2	conceived the study|designed and performed the experiments|analyzed the data and wrote the manuscript	designed and performed the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5847638	29532188	JB	2	conceived the study|designed and performed the experiments|analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5847638	29532188	JN	2	conceived the study|supervised the project|analyzed the data and wrote the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5847638	29532188	JN	2	conceived the study|supervised the project|analyzed the data and wrote the manuscript	supervised the project	-	Supervision	YES
5847638	29532188	JN	2	conceived the study|supervised the project|analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5847638	29532188	MH	2	designed and performed the experiments|analyzed the data and wrote the manuscript	designed and performed the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5847638	29532188	MH	2	designed and performed the experiments|analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5182435	27920384	All authors	2	have participated in discussing the ideas for this study and in preparing the manuscript	have participated in discussing the ideas for this study and in preparing the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5780745	29363419	KC	2	analyzed the results	analyzed the results	Analyzed the data	Formal analysis	YES
5780745	29363419	LL	2	analyzed the results	analyzed the results	Analyzed the data	Formal analysis	YES
5780745	29363419	PL	2	collected the plant samples and extracted rnas for high throughput sequencing	collected the plant samples and extracted rnas for high throughput sequencing	Performed the experiments	Investigation	YES
5780745	29363419	RNA	2	targets using the degradome profile	targets using the degradome profile	-	-	NO
5780745	29363419	SL	2	collected the plant samples and extracted rnas for high throughput sequencing	collected the plant samples and extracted rnas for high throughput sequencing	Performed the experiments	Investigation	YES
5780745	29363419	XC	2	conceived of and designed the research|collected the plant samples and extracted rnas for high throughput sequencing	conceived of and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5780745	29363419	XC	2	conceived of and designed the research|collected the plant samples and extracted rnas for high throughput sequencing	collected the plant samples and extracted rnas for high throughput sequencing	Performed the experiments	Investigation	YES
5780745	29363419	XZ	2	analyzed the results	analyzed the results	Analyzed the data	Formal analysis	YES
5780745	29363419	YL	2	conceived of and designed the research|performed the rlm 5-race experiments|wrote the manuscript	conceived of and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5780745	29363419	YL	2	conceived of and designed the research|performed the rlm 5-race experiments|wrote the manuscript	performed the rlm 5-race experiments	Performed the experiments	Investigation	YES
5780745	29363419	YL	2	conceived of and designed the research|performed the rlm 5-race experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5780745	29363419	YY	2	performed the rlm 5-race experiments	performed the rlm 5-race experiments	Performed the experiments	Investigation	YES
5780745	29363419	YZ	2	conceived of and designed the research|designed the computational pipeline for analyzing small rna sequencing profiles and degradome profile|analyzed the results|wrote the manuscript	conceived of and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5780745	29363419	YZ	2	conceived of and designed the research|designed the computational pipeline for analyzing small rna sequencing profiles and degradome profile|analyzed the results|wrote the manuscript	designed the computational pipeline for analyzing small rna sequencing profiles and degradome profile	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5780745	29363419	YZ	2	conceived of and designed the research|designed the computational pipeline for analyzing small rna sequencing profiles and degradome profile|analyzed the results|wrote the manuscript	analyzed the results	Analyzed the data	Formal analysis	YES
5780745	29363419	YZ	2	conceived of and designed the research|designed the computational pipeline for analyzing small rna sequencing profiles and degradome profile|analyzed the results|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3494874	23023917	AM	2	designed, analysed and interpreted and were responsible for drafting the article|were responsible for data acquisition	designed, analysed and interpreted and were responsible for drafting the article	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3494874	23023917	AM	2	designed, analysed and interpreted and were responsible for drafting the article|were responsible for data acquisition	were responsible for data acquisition	Performed the experiments	Investigation	YES
3494874	23023917	AWH	2	designed, analysed and interpreted and were responsible for drafting the article	designed, analysed and interpreted and were responsible for drafting the article	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3494874	23023917	All authors	2	critically revised the article and finally approved the manuscript prior to publication	critically revised the article and finally approved the manuscript prior to publication	Wrote the paper	Writing - Review & Editing	YES
3494874	23023917	AvM	2	designed, analysed and interpreted and were responsible for drafting the article	designed, analysed and interpreted and were responsible for drafting the article	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3494874	23023917	EAdV	2	were responsible for data acquisition	were responsible for data acquisition	Performed the experiments	Investigation	YES
3494874	23023917	GP	2	designed, analysed and interpreted and were responsible for drafting the article	designed, analysed and interpreted and were responsible for drafting the article	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3494874	23023917	JPGS	2	designed, analysed and interpreted and were responsible for drafting the article	designed, analysed and interpreted and were responsible for drafting the article	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3494874	23023917	MIFJO	2	designed, analysed and interpreted and were responsible for drafting the article|were responsible for data acquisition	designed, analysed and interpreted and were responsible for drafting the article	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3494874	23023917	MIFJO	2	designed, analysed and interpreted and were responsible for drafting the article|were responsible for data acquisition	were responsible for data acquisition	Performed the experiments	Investigation	YES
3494874	23023917	MSD	2	were responsible for data acquisition	were responsible for data acquisition	Performed the experiments	Investigation	YES
3494874	23023917	PAD	2	designed, analysed and interpreted and were responsible for drafting the article	designed, analysed and interpreted and were responsible for drafting the article	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
1989141	17912359	BQ	PLoS5	Performed the experiments|Analyzed the data|Developed and implemented the structure prediction method described	Performed the experiments	Performed the experiments	Investigation	YES
1989141	17912359	BQ	PLoS5	Performed the experiments|Analyzed the data|Developed and implemented the structure prediction method described	Analyzed the data	Analyzed the data	Formal analysis	YES
1989141	17912359	BQ	PLoS5	Performed the experiments|Analyzed the data|Developed and implemented the structure prediction method described	Developed and implemented the structure prediction method described	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
1989141	17912359	DB	PLoS5	Developed and implemented the structure prediction method described	Developed and implemented the structure prediction method described	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
1989141	17912359	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Developed and implemented the structure prediction method described	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1989141	17912359	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Developed and implemented the structure prediction method described	Performed the experiments	Performed the experiments	Investigation	YES
1989141	17912359	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Developed and implemented the structure prediction method described	Analyzed the data	Analyzed the data	Formal analysis	YES
1989141	17912359	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Developed and implemented the structure prediction method described	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1989141	17912359	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Developed and implemented the structure prediction method described	Developed and implemented the structure prediction method described	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
1989141	17912359	RK	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5818430	29497439	All authors	2	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
3567760	23361237	AF	2	expertise on fatty liver and liver transplantation	expertise on fatty liver and liver transplantation	-	-	NO
3567760	23361237	DN	2	expertise on fatty liver and liver transplantation	expertise on fatty liver and liver transplantation	-	-	NO
3567760	23361237	EC	2	expertise on liver morphology and functionality	expertise on liver morphology and functionality	Performed the experiments	Investigation	YES
3567760	23361237	ET	2	tissue preparation morphology, enzyme and immunohistochemical analyses|final manuscript writing|contributed equally to the present work	tissue preparation morphology, enzyme and immunohistochemical analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3567760	23361237	ET	2	tissue preparation morphology, enzyme and immunohistochemical analyses|final manuscript writing|contributed equally to the present work	final manuscript writing	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3567760	23361237	ET	2	tissue preparation morphology, enzyme and immunohistochemical analyses|final manuscript writing|contributed equally to the present work	contributed equally to the present work	-	-	NO
3567760	23361237	GM	2	tissue preparation morphology, enzyme and immunohistochemical analyses	tissue preparation morphology, enzyme and immunohistochemical analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3567760	23361237	IF	2	study conception and design|final manuscript writing	study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
3567760	23361237	IF	2	study conception and design|final manuscript writing	final manuscript writing	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3567760	23361237	MV	2	expertise on fatty liver and liver transplantation	expertise on fatty liver and liver transplantation	-	-	NO
3567760	23361237	SB	2	expertise on liver morphology and functionality	expertise on liver morphology and functionality	Performed the experiments	Investigation	YES
3567760	23361237	VB	2	tissue preparation morphology, enzyme and immunohistochemical analyses|final manuscript writing|contributed equally to the present work	tissue preparation morphology, enzyme and immunohistochemical analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3567760	23361237	VB	2	tissue preparation morphology, enzyme and immunohistochemical analyses|final manuscript writing|contributed equally to the present work	final manuscript writing	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3567760	23361237	VB	2	tissue preparation morphology, enzyme and immunohistochemical analyses|final manuscript writing|contributed equally to the present work	contributed equally to the present work	-	-	NO
5182438	27920387	All authors	2	drafted the manuscript and gave final approval for publication	drafted the manuscript and gave final approval for publication	Wrote the paper	Writing - Original Draft	YES
5182438	27920387	G.R.	2	carried out the fieldwork	carried out the fieldwork	Performed the experiments	Investigation	YES
5182438	27920387	P.B.H.	2	carried out the molecular laboratory work and participated in data analysis	carried out the molecular laboratory work and participated in data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5182438	27920387	T.U.W.	2	carried out the molecular laboratory work and participated in data analysis	carried out the molecular laboratory work and participated in data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4418594	25938595	AS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418594	25938595	AS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418594	25938595	AS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418594	25938595	CDF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418594	25938595	CDF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418594	25938595	CDF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418594	25938595	CDF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418594	25938595	JJH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418594	25938595	JJH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418594	25938595	JS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4418594	25938595	JS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418594	25938595	LH	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4418594	25938595	LH	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418594	25938595	LK	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418594	25938595	LLB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418594	25938595	LLB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418594	25938595	LLB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418594	25938595	LLB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418594	25938595	SG	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4418594	25938595	SG	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418594	25938595	TSA	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4418594	25938595	TSA	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418594	25938595	YYS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418594	25938595	YYS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4418594	25938595	YYS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
3494875	23027640	FM	PLoS52	performed experiments	performed experiments	Performed the experiments	Investigation	YES
3494875	23027640	KNW	PLoS52	planned and designed experiments|performed experiments|analyzed the data|wrote the paper	planned and designed experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
3494875	23027640	KNW	PLoS52	planned and designed experiments|performed experiments|analyzed the data|wrote the paper	performed experiments	Performed the experiments	Investigation	YES
3494875	23027640	KNW	PLoS52	planned and designed experiments|performed experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
3494875	23027640	KNW	PLoS52	planned and designed experiments|performed experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3494875	23027640	MvW	PLoS52	performed experiments|wrote the paper	performed experiments	Performed the experiments	Investigation	YES
3494875	23027640	MvW	PLoS52	performed experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3494875	23027640	NO	PLoS52	performed experiments	performed experiments	Performed the experiments	Investigation	YES
3494875	23027640	TB	PLoS52	synthesized and provided chemicals	synthesized and provided chemicals	Performed the experiments	Investigation	YES
3494875	23027640	TG	PLoS52	planned and designed experiments|performed experiments|analyzed the data|wrote the paper	planned and designed experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
3494875	23027640	TG	PLoS52	planned and designed experiments|performed experiments|analyzed the data|wrote the paper	performed experiments	Performed the experiments	Investigation	YES
3494875	23027640	TG	PLoS52	planned and designed experiments|performed experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
3494875	23027640	TG	PLoS52	planned and designed experiments|performed experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3494875	23027640	UW	PLoS52	planned and designed experiments|analyzed the data|wrote the paper	planned and designed experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
3494875	23027640	UW	PLoS52	planned and designed experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
3494875	23027640	UW	PLoS52	planned and designed experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3494875	23027640	VB	PLoS52	synthesized and provided chemicals	synthesized and provided chemicals	Performed the experiments	Investigation	YES
5849584	29536381	AI	2	studied the bioinformatics	studied the bioinformatics	-	Formal analysis	YES
5849584	29536381	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5849584	29536381	JT	2	conceived and designed the study|edited the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5849584	29536381	JT	2	conceived and designed the study|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5780746	29363421	AMK	1	Supervised the research|Data analysis|Writing|Review the manuscript	Supervised the research	-	Supervision	YES
5780746	29363421	AMK	1	Supervised the research|Data analysis|Writing|Review the manuscript	Data analysis	Analyzed the data	Formal analysis	YES
5780746	29363421	AMK	1	Supervised the research|Data analysis|Writing|Review the manuscript	Writing	Wrote the paper	-	YES
5780746	29363421	AMK	1	Supervised the research|Data analysis|Writing|Review the manuscript	Review the manuscript	Wrote the paper	Writing - Review & Editing	YES
5780746	29363421	WCL	1	Data analysis|Writing|Review the manuscript	Data analysis	Analyzed the data	Formal analysis	YES
5780746	29363421	WCL	1	Data analysis|Writing|Review the manuscript	Writing	Wrote the paper	-	YES
5780746	29363421	WCL	1	Data analysis|Writing|Review the manuscript	Review the manuscript	Wrote the paper	Writing - Review & Editing	YES
1989142	17912350	HT	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1989142	17912350	HT	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1989142	17912350	MD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1989142	17912350	MD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1989142	17912350	MD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1989142	17912350	MD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1989142	17912350	MD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5818461	29497436	LM	2	performed genome assembly	performed genome assembly	Performed the experiments	Investigation	YES
5818461	29497436	SO-A	2	performed bioinformatics	performed bioinformatics	Performed the experiments	Formal analysis|Investigation	YES
5818461	29497436	SS	2	performed genome assembly	performed genome assembly	Performed the experiments	Investigation	YES
5206269	28044012	Both authors	2	contributed to the conception and structure of this review, drafting of the text and final review of the article	contributed to the conception and structure of this review, drafting of the text and final review of the article	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
6270793	25302701	A.N.	2	performed the adsorption experiments, arsenic analyses and wrote the paper	performed the adsorption experiments, arsenic analyses and wrote the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6270793	25302701	C.M.D.	2	initiated and supervised the posdru project, this publication being part of this project|conceived and designed the impregnation process and wrote the paper	initiated and supervised the posdru project, this publication being part of this project	Conceived and designed the experiments	Conceptualization|Supervision	YES
6270793	25302701	C.M.D.	2	initiated and supervised the posdru project, this publication being part of this project|conceived and designed the impregnation process and wrote the paper	conceived and designed the impregnation process and wrote the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
6270793	25302701	L.L.	2	fitted and interpreted the experimental data and wrote and edited the manuscript	fitted and interpreted the experimental data and wrote and edited the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
6270793	25302701	M.C.	2	performed the adsorption experiments, arsenic analyses and wrote the paper	performed the adsorption experiments, arsenic analyses and wrote the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6270793	25302701	P.N.	2	conceived and designed the impregnation process and wrote the paper|analyzed and interpreted the characterization of the obtained adsorbent material	conceived and designed the impregnation process and wrote the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
6270793	25302701	P.N.	2	conceived and designed the impregnation process and wrote the paper|analyzed and interpreted the characterization of the obtained adsorbent material	analyzed and interpreted the characterization of the obtained adsorbent material	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3567762	23361239	ACS	2	experiments performance, data analysis, manuscript correction and final approval	experiments performance, data analysis, manuscript correction and final approval	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
3567762	23361239	EE	2	experiments performance, data analysis, manuscript correction and final approval	experiments performance, data analysis, manuscript correction and final approval	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
3567762	23361239	EPCF	2	experiments performance, data analysis, manuscript correction and final approval	experiments performance, data analysis, manuscript correction and final approval	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
3567762	23361239	MBSS	2	experiments design, data analysis, manuscript writing and correction and final approval	experiments design, data analysis, manuscript writing and correction and final approval	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
3567762	23361239	MJAR	2	study planning, experiments design, data analysis, writing and correcting the manuscript, providing the final version	study planning, experiments design, data analysis, writing and correcting the manuscript, providing the final version	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
3567762	23361239	MMI	2	experiments design, data analysis, manuscript writing and correction and final approval	experiments design, data analysis, manuscript writing and correction and final approval	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
1989143	17912351	CL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1989143	17912351	CL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1989143	17912351	CL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1989143	17912351	JS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1989143	17912351	JS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1989143	17912351	JS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1989143	17912351	KJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1989143	17912351	KJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1989143	17912351	KJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1989143	17912351	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1989143	17912351	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1989143	17912351	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1989143	17912351	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418595	25938664	AS	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418595	25938664	AS	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418595	25938664	FE	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418595	25938664	LC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418595	25938664	LF	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418595	25938664	LG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418595	25938664	LG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418595	25938664	LG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418595	25938664	LG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418595	25938664	LG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418595	25938664	LP	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418595	25938664	MD	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4418595	25938664	MD	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418595	25938664	MF	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418595	25938664	MM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418595	25938664	NR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418595	25938664	NR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418595	25938664	NR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418595	25938664	RR	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418595	25938664	SM	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418595	25938664	SM	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5780747	29363431	JWu	2	designed the study|wrote and edited the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5780747	29363431	JWu	2	designed the study|wrote and edited the manuscript	wrote and edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5780747	29363431	JX	2	designed the study|wrote and edited the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5780747	29363431	JX	2	designed the study|wrote and edited the manuscript	wrote and edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5780747	29363431	JY	2	designed the study|wrote and edited the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5780747	29363431	JY	2	designed the study|wrote and edited the manuscript	wrote and edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5780747	29363431	YBZ	2	designed the study|performed analyses described in this manuscript|wrote and edited the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5780747	29363431	YBZ	2	designed the study|performed analyses described in this manuscript|wrote and edited the manuscript	performed analyses described in this manuscript	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5780747	29363431	YBZ	2	designed the study|performed analyses described in this manuscript|wrote and edited the manuscript	wrote and edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5780747	29363431	YDZ	2	performed analyses described in this manuscript	performed analyses described in this manuscript	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5849585	29536215	All	2	data are shown in figures and tables within this article	data are shown in figures and tables within this article	-	Visualization	YES
5849585	29536215	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5849585	29536215	BY	2	reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5849585	29536215	HD	2	reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5849585	29536215	HL	2	reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5849585	29536215	ML	2	designed the work|performed the experiments and analyzed the data|wrote the manuscript	designed the work	Conceived and designed the experiments	-	YES
5849585	29536215	ML	2	designed the work|performed the experiments and analyzed the data|wrote the manuscript	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5849585	29536215	ML	2	designed the work|performed the experiments and analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5849585	29536215	RM	2	reviewed and edited the manuscript|wrote the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5849585	29536215	RM	2	reviewed and edited the manuscript|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5849585	29536215	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5849585	29536215	XS	2	designed the work|wrote the manuscript	designed the work	Conceived and designed the experiments	-	YES
5849585	29536215	XS	2	designed the work|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3494876	23065768	CP	2	performed most of the experiments of the paper	performed most of the experiments of the paper	Performed the experiments	Investigation	YES
3494876	23065768	EL	2	analysed the data and wrote the manuscript	analysed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3494876	23065768	EM	2	performed statistical analysis	performed statistical analysis	Analyzed the data	Formal analysis	YES
3494876	23065768	IT	2	analysed the data and wrote the manuscript	analysed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3494876	23065768	KBB	2	performed biochemical experiments	performed biochemical experiments	Performed the experiments	Investigation	YES
3494876	23065768	LC	2	analysed the data and wrote the manuscript	analysed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3494876	23065768	MLR	2	analysed the data and wrote the manuscript|supervised the work	analysed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3494876	23065768	MLR	2	analysed the data and wrote the manuscript|supervised the work	supervised the work	-	Supervision	YES
3494876	23065768	OT	2	analysed the data and wrote the manuscript	analysed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3494876	23065768	SC	2	performed statistical analysis|analysed the data and wrote the manuscript	performed statistical analysis	Analyzed the data	Formal analysis	YES
3494876	23065768	SC	2	performed statistical analysis|analysed the data and wrote the manuscript	analysed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3494876	23065768	SGL	2	performed ihc experiments	performed ihc experiments	Performed the experiments	Investigation	YES
4641171	26605329	All authors	2	contributed to the analysis and interpretation of the data and critical revision and final approval of the paper	contributed to the analysis and interpretation of the data and critical revision and final approval of the paper	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
4641171	26605329	Chun-Ju Chiang	2	carried out the data collection and performed the statistical analysis	carried out the data collection and performed the statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4641171	26605329	Hung-Yi Chuang	2	participated in the conception and design of the study	participated in the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4641171	26605329	Kai-Wen Chuang	2	carried out the data collection and performed the statistical analysis	carried out the data collection and performed the statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4641171	26605329	Sheng-Nan Lu	2	participated in the conception and design of the study	participated in the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4641171	26605329	Yit-Sheung Yap	2	participated in the conception and design of the study, drafted, and wrote the paper	participated in the conception and design of the study, drafted, and wrote the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
6270794	25438084	E. Zagar	2	designed research and synthetic approach, analyzed the data and wrote the paper	designed research and synthetic approach, analyzed the data and wrote the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
6270794	25438084	P. Perdih	2	designed research and synthetic approach, analyzed the data and wrote the paper	designed research and synthetic approach, analyzed the data and wrote the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5206272	28044015	A.T.P.	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5206272	28044015	L.M.	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5206272	28044015	L.S.P.	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
1991584	17912361	AB	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1991584	17912361	AM	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1991584	17912361	AM	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1991584	17912361	BK	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1991584	17912361	BK	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1991584	17912361	CB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1991584	17912361	EI	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1991584	17912361	HY	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1991584	17912361	LD	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1991584	17912361	SL	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1991584	17912361	SL	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1991584	17912361	TD	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1991584	17912361	TH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1991584	17912361	TH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1991584	17912361	TH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1991584	17912361	TH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1991584	17912361	TM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418596	25938240	AM	PLoS5	Wrote the paper|Developed the study methodology	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418596	25938240	AM	PLoS5	Wrote the paper|Developed the study methodology	Developed the study methodology	Performed the experiments	Methodology	YES
4418596	25938240	DC	PLoS5	Wrote the paper|Conceived the original idea for the study	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418596	25938240	DC	PLoS5	Wrote the paper|Conceived the original idea for the study	Conceived the original idea for the study	Conceived and designed the experiments	Conceptualization	YES
4418596	25938240	DL	PLoS5	Analyzed the data|Wrote the paper|Developed the study methodology	Analyzed the data	Analyzed the data	Formal analysis	YES
4418596	25938240	DL	PLoS5	Analyzed the data|Wrote the paper|Developed the study methodology	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418596	25938240	DL	PLoS5	Analyzed the data|Wrote the paper|Developed the study methodology	Developed the study methodology	Performed the experiments	Methodology	YES
4418596	25938240	HH	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418596	25938240	KBDH	PLoS5	Analyzed the data|Wrote the paper|Developed the study methodology	Analyzed the data	Analyzed the data	Formal analysis	YES
4418596	25938240	KBDH	PLoS5	Analyzed the data|Wrote the paper|Developed the study methodology	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418596	25938240	KBDH	PLoS5	Analyzed the data|Wrote the paper|Developed the study methodology	Developed the study methodology	Performed the experiments	Methodology	YES
4418596	25938240	KH	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418596	25938240	SZ	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418596	25938240	WR	PLoS5	Analyzed the data|Wrote the paper|Developed the study methodology	Analyzed the data	Analyzed the data	Formal analysis	YES
4418596	25938240	WR	PLoS5	Analyzed the data|Wrote the paper|Developed the study methodology	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418596	25938240	WR	PLoS5	Analyzed the data|Wrote the paper|Developed the study methodology	Developed the study methodology	Performed the experiments	Methodology	YES
1991585	17912373	DM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1991585	17912373	GM	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1991585	17912373	GM	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1991585	17912373	IM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1991585	17912373	IM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1991585	17912373	IM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1991585	17912373	LC	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1991585	17912373	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1991585	17912373	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1991585	17912373	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1991585	17912373	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1991585	17912373	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1991585	17912373	RR	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5849708	29536208	All authors	2	read and approved the manuscript	read and approved the manuscript	-	-	NO
5849708	29536208	GX	2	contributed equally to the work|conducted literature research, experimental studies, data acquisition, and statistical analysis	contributed equally to the work	-	-	NO
5849708	29536208	GX	2	contributed equally to the work|conducted literature research, experimental studies, data acquisition, and statistical analysis	conducted literature research, experimental studies, data acquisition, and statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5849708	29536208	K.C.	2	at ningbo university	at ningbo university	-	-	NO
5849708	29536208	PW	2	reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5849708	29536208	RL	2	worked primarily on experimental studies and data acquisition	worked primarily on experimental studies and data acquisition	Performed the experiments	Investigation	YES
5849708	29536208	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5849708	29536208	Wong Magna Fund	2	at ningbo university	at ningbo university	-	-	NO
5849708	29536208	XZ	2	reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5849708	29536208	YM	2	contributed equally to the work|contributed to experimental design, data analysis/interpretation, manuscript preparation, and manuscript editing	contributed equally to the work	-	-	NO
5849708	29536208	YM	2	contributed equally to the work|contributed to experimental design, data analysis/interpretation, manuscript preparation, and manuscript editing	contributed to experimental design, data analysis/interpretation, manuscript preparation, and manuscript editing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5849708	29536208	ZW	2	conceived and designed the study, and was the guarantor of integrity for the entire project	conceived and designed the study, and was the guarantor of integrity for the entire project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5780748	29363427	CW	2	developed the algorithms and drafted the manuscript	developed the algorithms and drafted the manuscript	Contributed reagents/materials/analysis tools|Wrote the paper	Software|Writing - Original Draft	YES
5780748	29363427	GL	2	developed the algorithms and drafted the manuscript	developed the algorithms and drafted the manuscript	Contributed reagents/materials/analysis tools|Wrote the paper	Software|Writing - Original Draft	YES
5780748	29363427	WZ	2	proposed the idea of the project, prepared the 500 5x whole-genome dataset for testing, drafted the discussion and revised the whole manuscript	proposed the idea of the project, prepared the 500 5x whole-genome dataset for testing, drafted the discussion and revised the whole manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5780748	29363427	YW	2	developed the algorithms and drafted the manuscript	developed the algorithms and drafted the manuscript	Contributed reagents/materials/analysis tools|Wrote the paper	Software|Writing - Original Draft	YES
5780748	29363427	ZS	2	proposed the idea of the project, prepared the 500 5x whole-genome dataset for testing, drafted the discussion and revised the whole manuscript	proposed the idea of the project, prepared the 500 5x whole-genome dataset for testing, drafted the discussion and revised the whole manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
3494877	23125021	AC	2	provided technical assistance with immunohistochemistry data	provided technical assistance with immunohistochemistry data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
3494877	23125021	ADB	2	provided technical assistance with immunohistochemistry data	provided technical assistance with immunohistochemistry data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
3494877	23125021	BA	2	provided technical assistance with breast cancer tissues	provided technical assistance with breast cancer tissues	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
3494877	23125021	ED	2	provided conceptual advice and help to revise the manuscript|supervised the bioinformatics analysis	provided conceptual advice and help to revise the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
3494877	23125021	ED	2	provided conceptual advice and help to revise the manuscript|supervised the bioinformatics analysis	supervised the bioinformatics analysis	-	Formal analysis|Supervision	YES
3494877	23125021	FB	2	designed and carried out biological and functional experiments, analysed data and wrote the manuscript	designed and carried out biological and functional experiments, analysed data and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
3494877	23125021	FDA	2	carried out the initial setting medip experiment	carried out the initial setting medip experiment	Performed the experiments	Investigation	YES
3494877	23125021	FM	2	provided technical assistance with xenograft experiment	provided technical assistance with xenograft experiment	Performed the experiments	Investigation	YES
3494877	23125021	GB	2	supervised the project and help to revise the manuscript	supervised the project and help to revise the manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
3494877	23125021	GF	2	provided conceptual advice and help to revise the manuscript	provided conceptual advice and help to revise the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
3494877	23125021	MM	2	provided breast cancer specimens and was responsible for the study concept of immunohistochemistry and for the interpretation of results	provided breast cancer specimens and was responsible for the study concept of immunohistochemistry and for the interpretation of results	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation	YES
3494877	23125021	NBBM	2	performed all the bioinformatics analysis and wrote part of the manuscript	performed all the bioinformatics analysis and wrote part of the manuscript	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3494877	23125021	PM	2	provided conceptual advice and help to revise the manuscript	provided conceptual advice and help to revise the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
3494877	23125021	RNA	2	overexpression experiments	overexpression experiments	Performed the experiments	Investigation	YES
3494877	23125021	RS	2	provided assistance with flow citometry experiments	provided assistance with flow citometry experiments	Performed the experiments	Investigation	YES
3494877	23125021	SG	2	provided technical assistance with xenograft experiment	provided technical assistance with xenograft experiment	Performed the experiments	Investigation	YES
3494877	23125021	SS	2	provided conceptual advice and help to revise the manuscript	provided conceptual advice and help to revise the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
3494877	23125021	VC	2	provided technical assistance with breast cancer tissues	provided technical assistance with breast cancer tissues	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
3494877	23125021	YY	2	provided conceptual advice and help to revise the manuscript	provided conceptual advice and help to revise the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5206273	28044016	A.B.	2	designed the experiment|acquired and analysed the data|interpreted the results, as well as writing and revising the article|approved the final version of the manuscript	designed the experiment	Conceived and designed the experiments	Methodology	YES
5206273	28044016	A.B.	2	designed the experiment|acquired and analysed the data|interpreted the results, as well as writing and revising the article|approved the final version of the manuscript	acquired and analysed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5206273	28044016	A.B.	2	designed the experiment|acquired and analysed the data|interpreted the results, as well as writing and revising the article|approved the final version of the manuscript	interpreted the results, as well as writing and revising the article	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5206273	28044016	A.B.	2	designed the experiment|acquired and analysed the data|interpreted the results, as well as writing and revising the article|approved the final version of the manuscript	approved the final version of the manuscript	-	-	NO
5206273	28044016	C.G.	2	designed the experiment|acquired and analysed the data|interpreted the results, as well as writing and revising the article|approved the final version of the manuscript	designed the experiment	Conceived and designed the experiments	Methodology	YES
5206273	28044016	C.G.	2	designed the experiment|acquired and analysed the data|interpreted the results, as well as writing and revising the article|approved the final version of the manuscript	acquired and analysed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5206273	28044016	C.G.	2	designed the experiment|acquired and analysed the data|interpreted the results, as well as writing and revising the article|approved the final version of the manuscript	interpreted the results, as well as writing and revising the article	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5206273	28044016	C.G.	2	designed the experiment|acquired and analysed the data|interpreted the results, as well as writing and revising the article|approved the final version of the manuscript	approved the final version of the manuscript	-	-	NO
5206273	28044016	K.F.	2	interpreted the results, as well as writing and revising the article|approved the final version of the manuscript	interpreted the results, as well as writing and revising the article	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5206273	28044016	K.F.	2	interpreted the results, as well as writing and revising the article|approved the final version of the manuscript	approved the final version of the manuscript	-	-	NO
5206273	28044016	M.C.	2	designed the experiment|interpreted the results, as well as writing and revising the article|approved the final version of the manuscript	designed the experiment	Conceived and designed the experiments	Methodology	YES
5206273	28044016	M.C.	2	designed the experiment|interpreted the results, as well as writing and revising the article|approved the final version of the manuscript	interpreted the results, as well as writing and revising the article	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5206273	28044016	M.C.	2	designed the experiment|interpreted the results, as well as writing and revising the article|approved the final version of the manuscript	approved the final version of the manuscript	-	-	NO
5206273	28044016	N.B.	2	designed the experiment|interpreted the results, as well as writing and revising the article|approved the final version of the manuscript	designed the experiment	Conceived and designed the experiments	Methodology	YES
5206273	28044016	N.B.	2	designed the experiment|interpreted the results, as well as writing and revising the article|approved the final version of the manuscript	interpreted the results, as well as writing and revising the article	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5206273	28044016	N.B.	2	designed the experiment|interpreted the results, as well as writing and revising the article|approved the final version of the manuscript	approved the final version of the manuscript	-	-	NO
5206273	28044016	R.S.	2	designed the experiment|acquired and analysed the data|interpreted the results, as well as writing and revising the article|approved the final version of the manuscript	designed the experiment	Conceived and designed the experiments	Methodology	YES
5206273	28044016	R.S.	2	designed the experiment|acquired and analysed the data|interpreted the results, as well as writing and revising the article|approved the final version of the manuscript	acquired and analysed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5206273	28044016	R.S.	2	designed the experiment|acquired and analysed the data|interpreted the results, as well as writing and revising the article|approved the final version of the manuscript	interpreted the results, as well as writing and revising the article	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5206273	28044016	R.S.	2	designed the experiment|acquired and analysed the data|interpreted the results, as well as writing and revising the article|approved the final version of the manuscript	approved the final version of the manuscript	-	-	NO
5818463	29497431	AC	7	contributed to the writing and the revision of the manuscript	contributed to the writing and the revision of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5818463	29497431	KaG	7	performed the experiments|contributed to the writing and the revision of the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5818463	29497431	KaG	7	performed the experiments|contributed to the writing and the revision of the manuscript	contributed to the writing and the revision of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5818463	29497431	KrG	7	conceived and designed the experiments|analyzed and discussed the results|contributed to the writing and the revision of the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5818463	29497431	KrG	7	conceived and designed the experiments|analyzed and discussed the results|contributed to the writing and the revision of the manuscript	analyzed and discussed the results	Analyzed the data	Formal analysis	YES
5818463	29497431	KrG	7	conceived and designed the experiments|analyzed and discussed the results|contributed to the writing and the revision of the manuscript	contributed to the writing and the revision of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5818463	29497431	MP-N	7	performed the experiments|analyzed and discussed the results|contributed to the writing and the revision of the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5818463	29497431	MP-N	7	performed the experiments|analyzed and discussed the results|contributed to the writing and the revision of the manuscript	analyzed and discussed the results	Analyzed the data	Formal analysis	YES
5818463	29497431	MP-N	7	performed the experiments|analyzed and discussed the results|contributed to the writing and the revision of the manuscript	contributed to the writing and the revision of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5818463	29497431	MZ	7	analyzed and discussed the results|contributed to the writing and the revision of the manuscript	analyzed and discussed the results	Analyzed the data	Formal analysis	YES
5818463	29497431	MZ	7	analyzed and discussed the results|contributed to the writing and the revision of the manuscript	contributed to the writing and the revision of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5818463	29497431	SB	7	analyzed and discussed the results|contributed to the writing and the revision of the manuscript	analyzed and discussed the results	Analyzed the data	Formal analysis	YES
5818463	29497431	SB	7	analyzed and discussed the results|contributed to the writing and the revision of the manuscript	contributed to the writing and the revision of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5818463	29497431	TL	7	conceived and designed the experiments|performed the experiments|analyzed and discussed the results|contributed to the writing and the revision of the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5818463	29497431	TL	7	conceived and designed the experiments|performed the experiments|analyzed and discussed the results|contributed to the writing and the revision of the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5818463	29497431	TL	7	conceived and designed the experiments|performed the experiments|analyzed and discussed the results|contributed to the writing and the revision of the manuscript	analyzed and discussed the results	Analyzed the data	Formal analysis	YES
5818463	29497431	TL	7	conceived and designed the experiments|performed the experiments|analyzed and discussed the results|contributed to the writing and the revision of the manuscript	contributed to the writing and the revision of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
1991586	17912339	CC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1991586	17912339	DC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1991586	17912339	LW	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1991586	17912339	LW	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1991586	17912339	LW	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1991586	17912339	SD	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5859003	29556854	All authors	PLoS52	reviewed the manuscript|read and approved the final manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5859003	29556854	All authors	PLoS52	reviewed the manuscript|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5859003	29556854	DG	PLoS52	performed analysis and interpretation of data	performed analysis and interpretation of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5859003	29556854	JWW	PLoS52	conceived and designed the research	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5859003	29556854	KYS	PLoS52	performed analysis and interpretation of data	performed analysis and interpretation of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5859003	29556854	LP	PLoS52	performed analysis and interpretation of data	performed analysis and interpretation of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5859003	29556854	MLY	PLoS52	performed the experiments|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5859003	29556854	MLY	PLoS52	performed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5859003	29556854	MXC	PLoS52	performed the experiments|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5859003	29556854	MXC	PLoS52	performed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5859003	29556854	SFJ	PLoS52	performed analysis and interpretation of data	performed analysis and interpretation of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5859003	29556854	XXY	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5859003	29556854	ZL	PLoS52	performed analysis and interpretation of data	performed analysis and interpretation of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5859003	29556854	ZP	PLoS52	conceived and designed the research|wrote the manuscript	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5859003	29556854	ZP	PLoS52	conceived and designed the research|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5206276	28044019	Both authors	2	gave final approval for publication	gave final approval for publication	-	-	NO
5206276	28044019	R.M.C.	2	conceived and wrote the manuscript together	conceived and wrote the manuscript together	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5206276	28044019	S.T.	2	conceived and wrote the manuscript together	conceived and wrote the manuscript together	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4418597	25938480	JHF	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418597	25938480	JZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418597	25938480	JZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418597	25938480	JZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418597	25938480	MC	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4418597	25938480	MC	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418597	25938480	RZL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418597	25938480	XYD	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418597	25938480	ZDC	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418597	25938480	ZDC	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6429598	30996972	All authors	2	participated in discussions of the research	participated in discussions of the research	-	-	NO
6429598	30996972	J.L.G.	2	conceived the idea|carried out the experiments|analyzed the experimental data and wrote the manuscript|supervised the whole project	conceived the idea	Conceived and designed the experiments	Conceptualization	YES
6429598	30996972	J.L.G.	2	conceived the idea|carried out the experiments|analyzed the experimental data and wrote the manuscript|supervised the whole project	carried out the experiments	Performed the experiments	Investigation	YES
6429598	30996972	J.L.G.	2	conceived the idea|carried out the experiments|analyzed the experimental data and wrote the manuscript|supervised the whole project	analyzed the experimental data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6429598	30996972	J.L.G.	2	conceived the idea|carried out the experiments|analyzed the experimental data and wrote the manuscript|supervised the whole project	supervised the whole project	-	Supervision	YES
6429598	30996972	J.Z.	2	helped collect xafs data	helped collect xafs data	Performed the experiments	Investigation	YES
6429598	30996972	K.M.	2	conceived the idea|carried out the experiments|analyzed the experimental data and wrote the manuscript	conceived the idea	Conceived and designed the experiments	Conceptualization	YES
6429598	30996972	K.M.	2	conceived the idea|carried out the experiments|analyzed the experimental data and wrote the manuscript	carried out the experiments	Performed the experiments	Investigation	YES
6429598	30996972	K.M.	2	conceived the idea|carried out the experiments|analyzed the experimental data and wrote the manuscript	analyzed the experimental data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6429598	30996972	L.R.Z.	2	helped collect xafs data	helped collect xafs data	Performed the experiments	Investigation	YES
6429598	30996972	N.T.	2	prepared the sputtered catalysts	prepared the sputtered catalysts	-	-	NO
6429598	30996972	Q.P.C.	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
6429598	30996972	T.A.	2	prepared the sputtered catalysts	prepared the sputtered catalysts	-	-	NO
6429598	30996972	T.D.	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
6429598	30996972	X.G.L.	2	conceived the idea|analyzed the experimental data and wrote the manuscript|supervised the whole project	conceived the idea	Conceived and designed the experiments	Conceptualization	YES
6429598	30996972	X.G.L.	2	conceived the idea|analyzed the experimental data and wrote the manuscript|supervised the whole project	analyzed the experimental data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6429598	30996972	X.G.L.	2	conceived the idea|analyzed the experimental data and wrote the manuscript|supervised the whole project	supervised the whole project	-	Supervision	YES
6429598	30996972	Y.T.	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
6429598	30996972	Z.J.	2	helped collect xafs data	helped collect xafs data	Performed the experiments	Investigation	YES
6429598	30996972	Z.J.Z.	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
4110703	24997476	CMF	2	made substantial contributions to conception and design, acquisition of data, analysis and interpretation of data, drafting of the manuscript, revising the manuscript, and gave final approval for publication	made substantial contributions to conception and design, acquisition of data, analysis and interpretation of data, drafting of the manuscript, revising the manuscript, and gave final approval for publication	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
4110703	24997476	CP	2	made substantial contributions to acquisition of data, revising the manuscript, and gave final approval for publication	made substantial contributions to acquisition of data, revising the manuscript, and gave final approval for publication	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Resources|Writing - Review & Editing	YES
4110703	24997476	DCM	2	made substantial contributions to conception and design, acquisition of data, analysis and interpretation of data, drafting of the manuscript, revising the manuscript, and gave final approval for publication	made substantial contributions to conception and design, acquisition of data, analysis and interpretation of data, drafting of the manuscript, revising the manuscript, and gave final approval for publication	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
4110703	24997476	EW	2	made substantial contributions to acquisition of data, revising the manuscript, and gave final approval for publication	made substantial contributions to acquisition of data, revising the manuscript, and gave final approval for publication	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Resources|Writing - Review & Editing	YES
4110703	24997476	JRM	2	made substantial contributions to conception and design, acquisition of data, analysis and interpretation of data, drafting of the manuscript, revising the manuscript, and gave final approval for publication	made substantial contributions to conception and design, acquisition of data, analysis and interpretation of data, drafting of the manuscript, revising the manuscript, and gave final approval for publication	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
4110703	24997476	JRV	2	made substantial contributions to analysis and interpretation of data, revising the manuscript, and gave final approval for publication	made substantial contributions to analysis and interpretation of data, revising the manuscript, and gave final approval for publication	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
4110703	24997476	KG	2	made substantial contributions to conception and design, acquisition of data, analysis and interpretation of data, drafting of the manuscript, revising the manuscript, and gave final approval for publication	made substantial contributions to conception and design, acquisition of data, analysis and interpretation of data, drafting of the manuscript, revising the manuscript, and gave final approval for publication	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
4110703	24997476	KSC	2	made substantial contributions to conception and design, acquisition of data, analysis and interpretation of data, drafting of the manuscript, revising the manuscript, and gave final approval for publication	made substantial contributions to conception and design, acquisition of data, analysis and interpretation of data, drafting of the manuscript, revising the manuscript, and gave final approval for publication	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
4110703	24997476	LB	2	made substantial contributions to acquisition of data, revising the manuscript, and gave final approval for publication	made substantial contributions to acquisition of data, revising the manuscript, and gave final approval for publication	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Resources|Writing - Review & Editing	YES
4110703	24997476	LT	2	made substantial contributions to acquisition of data, revising the manuscript, and gave final approval for publication	made substantial contributions to acquisition of data, revising the manuscript, and gave final approval for publication	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Resources|Writing - Review & Editing	YES
4110703	24997476	RD	2	made substantial contributions to conception and design, acquisition of data, analysis and interpretation of data, drafting of the manuscript, revising the manuscript, and gave final approval for publication	made substantial contributions to conception and design, acquisition of data, analysis and interpretation of data, drafting of the manuscript, revising the manuscript, and gave final approval for publication	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
4110703	24997476	RJS	2	made substantial contributions to conception and design, acquisition of data, analysis and interpretation of data, drafting of the manuscript, revising the manuscript, and gave final approval for publication	made substantial contributions to conception and design, acquisition of data, analysis and interpretation of data, drafting of the manuscript, revising the manuscript, and gave final approval for publication	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
4110703	24997476	YY	2	made substantial contributions to conception and design, acquisition of data, analysis and interpretation of data, drafting of the manuscript, revising the manuscript, and gave final approval for publication	made substantial contributions to conception and design, acquisition of data, analysis and interpretation of data, drafting of the manuscript, revising the manuscript, and gave final approval for publication	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5780764	29363430	HZ	2	helped analysis and revision of the manuscript	helped analysis and revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5780764	29363430	PH	2	conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5780764	29363430	RC	2	performed data analysis and drafted the manuscript	performed data analysis and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5780764	29363430	WZ	2	conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5780764	29363430	XL	2	directed analysis and revision of the manuscript	directed analysis and revision of the manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
5780764	29363430	YC	2	performed data analysis and drafted the manuscript	performed data analysis and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5780764	29363430	YH	2	performed data analysis and drafted the manuscript	performed data analysis and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5780764	29363430	YL	2	helped analysis and revision of the manuscript	helped analysis and revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5818465	29497434	EF	2	conceived, designed the study, and wrote the paper|performed the microscope observations and analyzed the data	conceived, designed the study, and wrote the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
5818465	29497434	EF	2	conceived, designed the study, and wrote the paper|performed the microscope observations and analyzed the data	performed the microscope observations and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5818465	29497434	JR	2	conceived, designed the study, and wrote the paper	conceived, designed the study, and wrote the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
5818465	29497434	MH	2	conceived, designed the study, and wrote the paper	conceived, designed the study, and wrote the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
6270797	24853615	Alexandra Yoon	2	helped write the manuscript	helped write the manuscript	Wrote the paper	Writing - Original Draft	YES
6270797	24853615	All authors	2	contributed to the research	contributed to the research	-	-	NO
6270797	24853615	Chris Abelt	2	was the primary author	was the primary author	Wrote the paper	Writing - Original Draft	YES
6270797	24853615	Joel Wagner	2	helped write the manuscript	helped write the manuscript	Wrote the paper	Writing - Original Draft	YES
6270797	24853615	Laura Whitworth	2	helped write the manuscript	helped write the manuscript	Wrote the paper	Writing - Original Draft	YES
3567765	23361242	JN	2	experiments outset and design|experiments performing|data analysis|manuscript writing	experiments outset and design	Conceived and designed the experiments	Methodology	YES
3567765	23361242	JN	2	experiments outset and design|experiments performing|data analysis|manuscript writing	experiments performing	Performed the experiments	Investigation	YES
3567765	23361242	JN	2	experiments outset and design|experiments performing|data analysis|manuscript writing	data analysis	Analyzed the data	Formal analysis	YES
3567765	23361242	JN	2	experiments outset and design|experiments performing|data analysis|manuscript writing	manuscript writing	Wrote the paper	Writing - Original Draft	YES
3567765	23361242	JZ	2	experiments outset and design|experiments performing|data analysis	experiments outset and design	Conceived and designed the experiments	Methodology	YES
3567765	23361242	JZ	2	experiments outset and design|experiments performing|data analysis	experiments performing	Performed the experiments	Investigation	YES
3567765	23361242	JZ	2	experiments outset and design|experiments performing|data analysis	data analysis	Analyzed the data	Formal analysis	YES
3567765	23361242	SX	2	experiments outset and design|manuscript writing	experiments outset and design	Conceived and designed the experiments	Methodology	YES
3567765	23361242	SX	2	experiments outset and design|manuscript writing	manuscript writing	Wrote the paper	Writing - Original Draft	YES
3567765	23361242	WL	2	experiments performing	experiments performing	Performed the experiments	Investigation	YES
3567765	23361242	YL	2	data analysis	data analysis	Analyzed the data	Formal analysis	YES
3567765	23361242	YX	2	experiments outset and design|manuscript writing	experiments outset and design	Conceived and designed the experiments	Methodology	YES
3567765	23361242	YX	2	experiments outset and design|manuscript writing	manuscript writing	Wrote the paper	Writing - Original Draft	YES
1991587	17912363	AW	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1991587	17912363	BO	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1991587	17912363	BO	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1991587	17912363	JF	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1991587	17912363	JF	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1991587	17912363	JF	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1991587	17912363	JW	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1991587	17912363	MT	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1991587	17912363	MT	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1991587	17912363	PH	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1991587	17912363	RL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1991587	17912363	RL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1991587	17912363	RL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1991587	17912363	RL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5861256	29556853	All	2	the data and materials referred in this manuscript were all availability|applicable international, national, and institutional guidelines for the care and use of animals were followed|animals were handled in strict accordance with good animal practice as defined by the relevant national and/or local animal welfare bodies	the data and materials referred in this manuscript were all availability	-	-	NO
5861256	29556853	All	2	the data and materials referred in this manuscript were all availability|applicable international, national, and institutional guidelines for the care and use of animals were followed|animals were handled in strict accordance with good animal practice as defined by the relevant national and/or local animal welfare bodies	applicable international, national, and institutional guidelines for the care and use of animals were followed	-	-	NO
5861256	29556853	All	2	the data and materials referred in this manuscript were all availability|applicable international, national, and institutional guidelines for the care and use of animals were followed|animals were handled in strict accordance with good animal practice as defined by the relevant national and/or local animal welfare bodies	animals were handled in strict accordance with good animal practice as defined by the relevant national and/or local animal welfare bodies	-	-	NO
5861256	29556853	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5861256	29556853	All the authors	2	are all agree for publication in this journal	are all agree for publication in this journal	-	-	NO
5861256	29556853	CX	2	operated the experiments	operated the experiments	Performed the experiments	Investigation	YES
5861256	29556853	LGH	2	were analyzed the datas	were analyzed the datas	Analyzed the data	Formal analysis	YES
5861256	29556853	LX	2	operated the experiments	operated the experiments	Performed the experiments	Investigation	YES
5861256	29556853	SF	2	were contributed in experiments designed and manuscripts writing	were contributed in experiments designed and manuscripts writing	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5861256	29556853	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5861256	29556853	ZY	2	were contributed in experiments designed and manuscripts writing	were contributed in experiments designed and manuscripts writing	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5206280	28044023	M.Y.	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5206280	28044023	R.V.	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5206280	28044023	Z.M.H.	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4641181	26605326	Heng Li	2	contributed equally to this work	contributed equally to this work	-	-	NO
4641181	26605326	Rining Zhu	2	contributed equally to this work	contributed equally to this work	-	-	NO
5819054	29497433	AS	7	Substantial contributions to the conception or design of the work; drafting the work; final approval of the version to be published; agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Substantial contributions to the conception or design of the work; drafting the work; final approval of the version to be published; agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5819054	29497433	FS	7	Interpretation of data; revised the article critically; final approval of the version to be published; agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Interpretation of data; revised the article critically; final approval of the version to be published; agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Analyzed the data|Wrote the paper	Data curation|Formal analysis|Writing - Review & Editing	YES
5819054	29497433	MD	7	Performed the analysis of iodine; revised the article critically; final approval of the version to be published	Performed the analysis of iodine; revised the article critically; final approval of the version to be published	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5819054	29497433	MR	7	revised the article critically; final approval of the version to be published; agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	revised the article critically; final approval of the version to be published; agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Wrote the paper	Writing - Review & Editing	YES
5819054	29497433	PS	7	Substantial contributions to the conception or design of the work; analysis and interpretation of data; final approval of the version to be published; agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Substantial contributions to the conception or design of the work; analysis and interpretation of data; final approval of the version to be published; agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Data curation|Formal analysis|Resources	YES
4418598	25938420	AT	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418598	25938420	BWP	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418598	25938420	C. Perret	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418598	25938420	C. Perret	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418598	25938420	C. Poitou	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418598	25938420	C. Poitou	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418598	25938420	EN	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418598	25938420	EN	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418598	25938420	FM	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418598	25938420	HD	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418598	25938420	JAW	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418598	25938420	JLB	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418598	25938420	KC	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418598	25938420	KC	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418598	25938420	LT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418598	25938420	LT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418598	25938420	LT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418598	25938420	NC	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418598	25938420	RA	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418598	25938420	VP	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418598	25938420	VT	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418598	25938420	YB	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
6270798	24705567	P.S.C.	1	Conception and design|Writing, review, and/or revision of the manuscript	Conception and design	Conceived and designed the experiments	Conceptualization	YES
6270798	24705567	P.S.C.	1	Conception and design|Writing, review, and/or revision of the manuscript	Writing, review, and/or revision of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6270798	24705567	S.L.	1	Data and its analysis|Writing, review, and/or revision of the manuscript	Data and its analysis	Analyzed the data	Formal analysis	YES
6270798	24705567	S.L.	1	Data and its analysis|Writing, review, and/or revision of the manuscript	Writing, review, and/or revision of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6270798	24705567	Z.L.	1	Conception and design|Data and its analysis|Writing, review, and/or revision of the manuscript	Conception and design	Conceived and designed the experiments	Conceptualization	YES
6270798	24705567	Z.L.	1	Conception and design|Data and its analysis|Writing, review, and/or revision of the manuscript	Data and its analysis	Analyzed the data	Formal analysis	YES
6270798	24705567	Z.L.	1	Conception and design|Data and its analysis|Writing, review, and/or revision of the manuscript	Writing, review, and/or revision of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3531601	23165884	JA	2	assisted pm, with	assisted pm, with	-	-	NO
3531601	23165884	MRE	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3531601	23165884	NWB	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3531601	23165884	SLJ	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3531601	23165884	TK	2	assisted pm, with	assisted pm, with	-	-	NO
1991588	17912341	AD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1991588	17912341	AD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1991588	17912341	AD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1991588	17912341	AD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1991588	17912341	AD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1991588	17912341	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1991588	17912341	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1991588	17912341	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1991588	17912341	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5861257	29560541	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5861257	29560541	JM	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5861257	29560541	JM	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5861257	29560541	JM	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5861257	29560541	JM	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5861257	29560541	JW	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5861257	29560541	The authors	PLoS52	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5861257	29560541	WC	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5861257	29560541	XH	PLoS52	conceived and designed the experiments|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5861257	29560541	XH	PLoS52	conceived and designed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3567767	23361244	DL	2	research performing	research performing	Performed the experiments	Investigation	YES
3567767	23361244	DML	2	research performing	research performing	Performed the experiments	Investigation	YES
3567767	23361244	EC	2	research performing|data analysis|manuscript writing	research performing	Performed the experiments	Investigation	YES
3567767	23361244	EC	2	research performing|data analysis|manuscript writing	data analysis	Analyzed the data	Formal analysis	YES
3567767	23361244	EC	2	research performing|data analysis|manuscript writing	manuscript writing	Wrote the paper	Writing - Original Draft	YES
3567767	23361244	ESR	2	research performing|participated in acquisition of funding|involved in manuscript editing and critical review	research performing	Performed the experiments	Investigation	YES
3567767	23361244	ESR	2	research performing|participated in acquisition of funding|involved in manuscript editing and critical review	participated in acquisition of funding	-	Funding acquisition	YES
3567767	23361244	ESR	2	research performing|participated in acquisition of funding|involved in manuscript editing and critical review	involved in manuscript editing and critical review	Wrote the paper	Writing - Review & Editing	YES
3567767	23361244	JPP	2	research performing|involved in manuscript editing and critical review	research performing	Performed the experiments	Investigation	YES
3567767	23361244	JPP	2	research performing|involved in manuscript editing and critical review	involved in manuscript editing and critical review	Wrote the paper	Writing - Review & Editing	YES
3567767	23361244	MC	2	research performing|data analysis	research performing	Performed the experiments	Investigation	YES
3567767	23361244	MC	2	research performing|data analysis	data analysis	Analyzed the data	Formal analysis	YES
3567767	23361244	NM	2	research performing|data analysis|manuscript writing	research performing	Performed the experiments	Investigation	YES
3567767	23361244	NM	2	research performing|data analysis|manuscript writing	data analysis	Analyzed the data	Formal analysis	YES
3567767	23361244	NM	2	research performing|data analysis|manuscript writing	manuscript writing	Wrote the paper	Writing - Original Draft	YES
3567767	23361244	RMB	2	research performing	research performing	Performed the experiments	Investigation	YES
3567767	23361244	VAM	2	research design|research performing|participated in acquisition of funding|data analysis|involved in manuscript editing and critical review|manuscript writing	research design	Conceived and designed the experiments	-	YES
3567767	23361244	VAM	2	research design|research performing|participated in acquisition of funding|data analysis|involved in manuscript editing and critical review|manuscript writing	research performing	Performed the experiments	Investigation	YES
3567767	23361244	VAM	2	research design|research performing|participated in acquisition of funding|data analysis|involved in manuscript editing and critical review|manuscript writing	participated in acquisition of funding	-	Funding acquisition	YES
3567767	23361244	VAM	2	research design|research performing|participated in acquisition of funding|data analysis|involved in manuscript editing and critical review|manuscript writing	data analysis	Analyzed the data	Formal analysis	YES
3567767	23361244	VAM	2	research design|research performing|participated in acquisition of funding|data analysis|involved in manuscript editing and critical review|manuscript writing	involved in manuscript editing and critical review	Wrote the paper	Writing - Review & Editing	YES
3567767	23361244	VAM	2	research design|research performing|participated in acquisition of funding|data analysis|involved in manuscript editing and critical review|manuscript writing	manuscript writing	Wrote the paper	Writing - Original Draft	YES
5780765	29363433	All authors	2	wrote, read, and approved the final version of the manuscript	wrote, read, and approved the final version of the manuscript	Wrote the paper	Writing - Original Draft	YES
5780765	29363433	JWKH	2	conceived the idea	conceived the idea	Conceived and designed the experiments	Conceptualization	YES
5780765	29363433	PL	2	conducted the study	conducted the study	Performed the experiments	Investigation	YES
5780765	29363433	XW	2	conceived the idea|designed and implemented the software pipeline|conducted the study	conceived the idea	Conceived and designed the experiments	Conceptualization	YES
5780765	29363433	XW	2	conceived the idea|designed and implemented the software pipeline|conducted the study	designed and implemented the software pipeline	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5780765	29363433	XW	2	conceived the idea|designed and implemented the software pipeline|conducted the study	conducted the study	Performed the experiments	Investigation	YES
4641208	26605332	All authors	2	contributed to the discussion of results and wrote and approved the paper	contributed to the discussion of results and wrote and approved the paper	Wrote the paper	Writing - Original Draft	YES
4641208	26605332	Anuj Sharma	2	contributed to the design of the study, developed the software framework, and performed the experiments	contributed to the design of the study, developed the software framework, and performed the experiments	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Software	YES
4641208	26605332	Elias S. Manolakos	2	conceived the study and contributed to the design and evaluation	conceived the study and contributed to the design and evaluation	Conceived and designed the experiments	Conceptualization|Methodology	YES
5247584	28093546	All authors	2	wrote the article and approved the final version	wrote the article and approved the final version	Wrote the paper	Writing - Original Draft	YES
5247584	28093546	S.Gr	2	recorded the in vivo intracellular data in vitro mepsp data	recorded the in vivo intracellular data in vitro mepsp data	Performed the experiments	Investigation	YES
1991589	17912364	AC	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1991589	17912364	AC	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1991589	17912364	AC	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1991589	17912364	EG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1991589	17912364	EG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1991589	17912364	ES	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1991589	17912364	ES	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1991589	17912364	KS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1991589	17912364	KS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5862715	29564574	All authors	2	made contributions to the experimental design, interpretation of the results and revisions of the manuscript|read and approved the final manuscript	made contributions to the experimental design, interpretation of the results and revisions of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Review & Editing	YES
5862715	29564574	All authors	2	made contributions to the experimental design, interpretation of the results and revisions of the manuscript|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5862715	29564574	PL	2	performed most lab work	performed most lab work	Performed the experiments	Investigation	YES
5862715	29564574	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5862715	29564574	YK	2	performed most lab work	performed most lab work	Performed the experiments	Investigation	YES
5862715	29564574	YM	2	designed the experiment and wrote the manuscript|performed most lab work	designed the experiment and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5862715	29564574	YM	2	designed the experiment and wrote the manuscript|performed most lab work	performed most lab work	Performed the experiments	Investigation	YES
4418599	25938418	ATB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418599	25938418	ATB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418599	25938418	ATB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418599	25938418	ATB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418599	25938418	EAL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418599	25938418	EAL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418599	25938418	EAL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418599	25938418	EG	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418599	25938418	EG	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3531602	23109291	AK	2	did experiments	did experiments	Performed the experiments	Investigation	YES
3531602	23109291	AMK	2	did experiments	did experiments	Performed the experiments	Investigation	YES
3531602	23109291	AS	2	did experiments	did experiments	Performed the experiments	Investigation	YES
3531602	23109291	ASK	2	designed the study, analysed the data and wrote the manuscript	designed the study, analysed the data and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3531602	23109291	JDF	2	were in charge of the immunochemistry analysis	were in charge of the immunochemistry analysis	Performed the experiments	Investigation	YES
3531602	23109291	JLP	2	designed the study, analysed the data and wrote the manuscript	designed the study, analysed the data and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3531602	23109291	JNS	2	designed the study, analysed the data and wrote the manuscript|did experiments	designed the study, analysed the data and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3531602	23109291	JNS	2	designed the study, analysed the data and wrote the manuscript|did experiments	did experiments	Performed the experiments	Investigation	YES
3531602	23109291	LM	2	were in charge of the immunochemistry analysis	were in charge of the immunochemistry analysis	Performed the experiments	Investigation	YES
3531602	23109291	MD	2	were in charge of the immunochemistry analysis	were in charge of the immunochemistry analysis	Performed the experiments	Investigation	YES
3531602	23109291	PSS	2	designed the study, analysed the data and wrote the manuscript|did experiments	designed the study, analysed the data and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3531602	23109291	PSS	2	designed the study, analysed the data and wrote the manuscript|did experiments	did experiments	Performed the experiments	Investigation	YES
3531602	23109291	TM	2	designed the study, analysed the data and wrote the manuscript	designed the study, analysed the data and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5780849	29363428	CC	2	directed analysis and revision of the manuscript	directed analysis and revision of the manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
5780849	29363428	JL	2	helped analysis, writing and revision of the manuscript	helped analysis, writing and revision of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5780849	29363428	PH	2	conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5780849	29363428	WZ	2	directed analysis and revision of the manuscript	directed analysis and revision of the manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
5780849	29363428	XL	2	helped analysis, writing and revision of the manuscript	helped analysis, writing and revision of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5780849	29363428	YC	2	built performed data analysis and drafted the manuscript	built performed data analysis and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5780849	29363428	YH	2	built performed data analysis and drafted the manuscript	built performed data analysis and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5780849	29363428	YL	2	built performed data analysis and drafted the manuscript	built performed data analysis and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5819319	29497435	AK	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5819319	29497435	DT	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5819319	29497435	HL	2	initiated and designed the experiment|revised the manuscript	initiated and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5819319	29497435	HL	2	initiated and designed the experiment|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5819319	29497435	XT	2	performed the experiments and collected the data	performed the experiments and collected the data	Performed the experiments	Investigation	YES
5819319	29497435	ZC	2	analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
416566	15169563	GB	2	conceived of the study, participated in the design and drafted the manuscript	conceived of the study, participated in the design and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
416566	15169563	LD	2	carried out the coding and statistical analysis, and participated in the drafting of the manuscript	carried out the coding and statistical analysis, and participated in the drafting of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
416566	15169563	RM	2	participated in the statistical analysis and in the coordination of the study	participated in the statistical analysis and in the coordination of the study	Analyzed the data	Formal analysis|Project administration	YES
6270800	25036155	All co-authors	2	participated in drafting, critically contributing to or revising the manuscript, and in approving the final content of the manuscript	participated in drafting, critically contributing to or revising the manuscript, and in approving the final content of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4418600	25938478	CH	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418600	25938478	CH	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418600	25938478	IM	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418600	25938478	IM	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418600	25938478	MSO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418600	25938478	MSO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418600	25938478	MSO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418600	25938478	MSO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418600	25938478	NH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418600	25938478	NH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418600	25938478	NH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418600	25938478	NM	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418600	25938478	NM	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418600	25938478	PS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418600	25938478	PS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418600	25938478	PS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418600	25938478	PS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418600	25938478	SW	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418600	25938478	SW	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418600	25938478	SW	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418600	25938478	SW	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418600	25938478	UA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418600	25938478	UA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418600	25938478	UA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418600	25938478	UA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418600	25938478	YD	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418600	25938478	YD	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418600	25938478	YD	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418600	25938478	YD	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418600	25938478	YH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418600	25938478	YH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418600	25938478	YH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418600	25938478	YH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1991590	17912365	EM	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1991590	17912365	EM	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1991590	17912365	IL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1991590	17912365	IL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1991590	17912365	IL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1991590	17912365	IL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1991590	17912365	ZL	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1991590	17912365	ZL	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
416567	15169562	DCM	2	participated in the collection of data and provided significant advice and consultation regarding the manuscript	participated in the collection of data and provided significant advice and consultation regarding the manuscript	Performed the experiments	Investigation	YES
416567	15169562	HW	2	provided significant advice and consultation regarding the manuscript	provided significant advice and consultation regarding the manuscript	-	-	NO
416567	15169562	LLB	2	designed the experiment and provided significant advice and consultation regarding the manuscript	designed the experiment and provided significant advice and consultation regarding the manuscript	Conceived and designed the experiments	Methodology	YES
416567	15169562	MLM	2	drafted the manuscript and participated in the collection and analysis of the data	drafted the manuscript and participated in the collection and analysis of the data	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
416567	15169562	YL	2	participated in the data analysis	participated in the data analysis	Analyzed the data	Formal analysis	YES
5864579	29569050	All	2	data are fully available without restriction	data are fully available without restriction	-	-	NO
5864579	29569050	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5864579	29569050	ELZ	2	performed the experiments and analyzed the raw data	performed the experiments and analyzed the raw data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5864579	29569050	GQL	2	participated in the design of the study	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
5864579	29569050	HHY	2	helped to perform the experiments	helped to perform the experiments	Performed the experiments	Investigation	YES
5864579	29569050	JJL	2	conceived the study, designed the experiments and drafted the manuscript	conceived the study, designed the experiments and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
5864579	29569050	KQZ	2	participated in the design of the study	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
5864579	29569050	SLZ	2	helped to perform the experiments	helped to perform the experiments	Performed the experiments	Investigation	YES
5864579	29569050	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5247591	28093553	A.V.	2	carried out intrinsic signal and two-photon imaging experiments as well as immunohistochemistry	carried out intrinsic signal and two-photon imaging experiments as well as immunohistochemistry	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
5247591	28093553	All authors	2	gave final approval for publication	gave final approval for publication	-	-	NO
5247591	28093553	F.S.	2	conceived of the study, designed and coordinated the study and drafted the manuscript	conceived of the study, designed and coordinated the study and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
5247591	28093553	I.E.	2	carried out intrinsic signal and two-photon imaging experiments, wrote image analysis software and contributed to drafting the manuscript	carried out intrinsic signal and two-photon imaging experiments, wrote image analysis software and contributed to drafting the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Software|Visualization|Writing - Original Draft	YES
5247591	28093553	V.L.	2	carried out intrinsic signal imaging experiments and immunohistochemistry	carried out intrinsic signal imaging experiments and immunohistochemistry	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
1991591	17912354	FP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1991591	17912354	FP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1991591	17912354	FP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1991591	17912354	FP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418601	25938231	CQZ	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4418601	25938231	CQZ	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418601	25938231	GHY	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418601	25938231	GYZ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418601	25938231	GYZ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418601	25938231	GYZ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418601	25938231	KXT	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418601	25938231	KXT	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418601	25938231	MFS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418601	25938231	QQL	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418601	25938231	QQL	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418601	25938231	RRL	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4418601	25938231	RRL	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
3531603	23065753	CC	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
3531603	23065753	CH	PLoS52	evaluated human nasopharyngeal carcinoma tissue sections	evaluated human nasopharyngeal carcinoma tissue sections	Performed the experiments	Investigation	YES
3531603	23065753	KPC	PLoS52	oversaw collection of clinical samples	oversaw collection of clinical samples	Performed the experiments	Investigation|Supervision	YES
3531603	23065753	LCC	PLoS52	designed this study|wrote the manuscript	designed this study	Conceived and designed the experiments	Methodology	YES
3531603	23065753	LCC	PLoS52	designed this study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3531603	23065753	NMT	PLoS52	oversaw collection of clinical samples	oversaw collection of clinical samples	Performed the experiments	Investigation|Supervision	YES
3531603	23065753	YL	PLoS52	supervised histological staining and analysis	supervised histological staining and analysis	Performed the experiments	Investigation|Supervision	YES
3531603	23065753	YSC	PLoS52	designed this study|wrote the manuscript|supervised the project	designed this study	Conceived and designed the experiments	Methodology	YES
3531603	23065753	YSC	PLoS52	designed this study|wrote the manuscript|supervised the project	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3531603	23065753	YSC	PLoS52	designed this study|wrote the manuscript|supervised the project	supervised the project	-	Supervision	YES
5780850	29363422	MK	2	constructed the database|analyzed transcriptome data	constructed the database	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5780850	29363422	MK	2	constructed the database|analyzed transcriptome data	analyzed transcriptome data	Analyzed the data	Formal analysis	YES
5780850	29363422	MM	2	conceived the study|revised the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5780850	29363422	MM	2	conceived the study|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5780850	29363422	NSL	2	carried out gene functional annotations	carried out gene functional annotations	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5780850	29363422	YM	2	analyzed transcriptome data|conceived the study|prepared the manuscript	analyzed transcriptome data	Analyzed the data	Formal analysis	YES
5780850	29363422	YM	2	analyzed transcriptome data|conceived the study|prepared the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5780850	29363422	YM	2	analyzed transcriptome data|conceived the study|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5820300	29503656	JF	2	contributed to the concept of the project and data interpretation, prepared the manuscript, and co-supervised the project	contributed to the concept of the project and data interpretation, prepared the manuscript, and co-supervised the project	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Resources|Supervision|Writing - Original Draft	YES
5820300	29503656	MD	2	designed the experiments and performed the optimization of the protocol and all experiments|contributed to the concept of the project and data interpretation, prepared the manuscript, and co-supervised the project	designed the experiments and performed the optimization of the protocol and all experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5820300	29503656	MD	2	designed the experiments and performed the optimization of the protocol and all experiments|contributed to the concept of the project and data interpretation, prepared the manuscript, and co-supervised the project	contributed to the concept of the project and data interpretation, prepared the manuscript, and co-supervised the project	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Resources|Supervision|Writing - Original Draft	YES
6270801	25232709	C.J.	2	wrote article	wrote article	Wrote the paper	Writing - Original Draft	YES
6270801	25232709	L.O.K.	2	wrote article	wrote article	Wrote the paper	Writing - Original Draft	YES
6270801	25232709	X.H.	2	performed experiments for figure 2	performed experiments for figure 2	Performed the experiments	Investigation|Visualization	YES
3683606	23549458	FG	2	cell culture, immunohistochemical study	cell culture, immunohistochemical study	Performed the experiments	Investigation	YES
3683606	23549458	MM	2	statistical analysis	statistical analysis	Analyzed the data	Formal analysis	YES
3683606	23549458	NM	2	soft agar colony assay, immunohistochemical study, statistical analysis	soft agar colony assay, immunohistochemical study, statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3683606	23549458	QY	2	cell culture, western blot analysis, cell cycle analysis	cell culture, western blot analysis, cell cycle analysis	Performed the experiments	Investigation	YES
3683606	23549458	SG	2	animal experiment	animal experiment	Performed the experiments	Investigation	YES
3683606	23549458	SH	2	cell culture, cell cycle analysis, soft agar colony assay, mouse tumor models, western blot analysis	cell culture, cell cycle analysis, soft agar colony assay, mouse tumor models, western blot analysis	Performed the experiments	Investigation|Methodology	YES
3683606	23549458	SK	2	immunohistochemical study	immunohistochemical study	Performed the experiments	Investigation	YES
3683606	23549458	SO	2	cell culture, western blot analysis, cell cycle analysis	cell culture, western blot analysis, cell cycle analysis	Performed the experiments	Investigation	YES
3683606	23549458	XX	2	cell culture	cell culture	Performed the experiments	Investigation	YES
416568	15169561	HH	2	discussed the idea, and participated in data analysis	discussed the idea, and participated in data analysis	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
416568	15169561	KF	2	assisted in drafting the paper and developing the analysis	assisted in drafting the paper and developing the analysis	Wrote the paper	Writing - Original Draft	YES
416568	15169561	LBA	2	collected all data, carried out the analyses, and made the first draft	collected all data, carried out the analyses, and made the first draft	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
416568	15169561	SEH	2	assisted with the statistical analysis and discussion of the concept	assisted with the statistical analysis and discussion of the concept	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
416568	15169561	VG	2	assisted in drafting the paper and developing the analysis	assisted in drafting the paper and developing the analysis	Wrote the paper	Writing - Original Draft	YES
1991593	17912355	DC	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1991593	17912355	DM	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1991593	17912355	DM	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1991593	17912355	FO	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1991593	17912355	FO	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1991593	17912355	FV	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1991593	17912355	FV	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1991593	17912355	FV	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1991593	17912355	GB	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1991593	17912355	GF	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1991593	17912355	GW	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1991593	17912355	GW	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1991593	17912355	IB	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1991593	17912355	JS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1991593	17912355	KM	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1991593	17912355	KT	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1991593	17912355	KT	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1991593	17912355	PA	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1991593	17912355	PB	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1991593	17912355	TH	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1991593	17912355	TW	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418602	25939029	LX	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418602	25939029	SL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418602	25939029	TL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418602	25939029	XQ	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418602	25939029	YD	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418602	25939029	YD	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418602	25939029	YL	PLoS5	Revised the manuscript	Revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4418602	25939029	YS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418602	25939029	YS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418602	25939029	YS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418602	25939029	YS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5247593	28093555	C.C.	PLoS52	performed the computational modelling|wrote the paper	performed the computational modelling	Performed the experiments	Formal analysis|Investigation|Methodology	YES
5247593	28093555	C.C.	PLoS52	performed the computational modelling|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5247593	28093555	M.H.	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5247593	28093555	T.B.	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5247593	28093555	T.R.	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5820301	29503659	All authors	2	participated in the discussion	participated in the discussion	-	-	NO
5820301	29503659	JS	2	conceived the study|prepared the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5820301	29503659	JS	2	conceived the study|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5820301	29503659	KR	2	prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5820301	29503659	YK	2	conceived the study|prepared the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5820301	29503659	YK	2	conceived the study|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
3531604	23129487	AJC	PLoS52	provided tumour samples|scored histopathological staining on tumour samples|provided critical discussion and edited the manuscript	provided tumour samples	Contributed reagents/materials/analysis tools	Resources	YES
3531604	23129487	AJC	PLoS52	provided tumour samples|scored histopathological staining on tumour samples|provided critical discussion and edited the manuscript	scored histopathological staining on tumour samples	Performed the experiments	Investigation	YES
3531604	23129487	AJC	PLoS52	provided tumour samples|scored histopathological staining on tumour samples|provided critical discussion and edited the manuscript	provided critical discussion and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
3531604	23129487	AKB	PLoS52	provided critical discussions and comments	provided critical discussions and comments	-	-	NO
3531604	23129487	JNA	PLoS52	provided critical discussion and edited the manuscript	provided critical discussion and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
3531604	23129487	MMS	PLoS52	scored histopathological staining on tumour samples|provided images of histopathology	scored histopathological staining on tumour samples	Performed the experiments	Investigation	YES
3531604	23129487	MMS	PLoS52	scored histopathological staining on tumour samples|provided images of histopathology	provided images of histopathology	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
3531604	23129487	PTY	PLoS52	initiated the project and planned the experiments|provided images of histopathology|wrote the paper	initiated the project and planned the experiments	Conceived and designed the experiments	Conceptualization	YES
3531604	23129487	PTY	PLoS52	initiated the project and planned the experiments|provided images of histopathology|wrote the paper	provided images of histopathology	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
3531604	23129487	PTY	PLoS52	initiated the project and planned the experiments|provided images of histopathology|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3531604	23129487	RAT	PLoS52	conducted xenograft studies	conducted xenograft studies	Performed the experiments	Investigation	YES
3531604	23129487	RTM	PLoS52	provided critical discussion and edited the manuscript	provided critical discussion and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5866258	29572689	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5866258	29572689	BS	PLoS52	conceived and designed the experiments, performed the experiments, analyzed the data, wrote the paper, prepared figures and/or tables, these authors contributed equally to this work	conceived and designed the experiments, performed the experiments, analyzed the data, wrote the paper, prepared figures and/or tables, these authors contributed equally to this work	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Visualization|Writing - Original Draft	YES
5866258	29572689	CTL	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5866258	29572689	DL	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5866258	29572689	FLS	PLoS52	conceived and designed the experiments, performed the experiments, analyzed the data, wrote the paper, prepared figures and/or tables, these authors contributed equally to this work	conceived and designed the experiments, performed the experiments, analyzed the data, wrote the paper, prepared figures and/or tables, these authors contributed equally to this work	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Visualization|Writing - Original Draft	YES
5866258	29572689	JQY	PLoS52	conceived and designed the experiments, performed the experiments, analyzed the data, wrote the paper, prepared figures and/or tables, these authors contributed equally to this work	conceived and designed the experiments, performed the experiments, analyzed the data, wrote the paper, prepared figures and/or tables, these authors contributed equally to this work	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Visualization|Writing - Original Draft	YES
5866258	29572689	LSM	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5866258	29572689	SX	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5866258	29572689	YL	PLoS52	conceived and designed the experiments, analyzed the data, contributed reagents/materials/analysis tools, wrote the paper, prepared figures and/or tables, reviewed drafts of the paper	conceived and designed the experiments, analyzed the data, contributed reagents/materials/analysis tools, wrote the paper, prepared figures and/or tables, reviewed drafts of the paper	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Methodology|Resources|Visualization|Writing - Original Draft|Writing - Review & Editing	YES
5866258	29572689	YPF	PLoS52	conceived and designed the experiments, analyzed the data, contributed reagents/materials/analysis tools, wrote the paper, prepared figures and/or tables, reviewed drafts of the paper	conceived and designed the experiments, analyzed the data, contributed reagents/materials/analysis tools, wrote the paper, prepared figures and/or tables, reviewed drafts of the paper	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Methodology|Resources|Visualization|Writing - Original Draft|Writing - Review & Editing	YES
5780851	29363432	CS	2	wrote manuscript|managed reviewer assignments and communication with authors	wrote manuscript	Wrote the paper	Writing - Original Draft	YES
5780851	29363432	CS	2	wrote manuscript|managed reviewer assignments and communication with authors	managed reviewer assignments and communication with authors	-	-	NO
5780851	29363432	JL	2	organized the conference	organized the conference	-	-	NO
5780851	29363432	LM	2	organized the conference	organized the conference	-	-	NO
5780851	29363432	MFS	2	managed reviewer assignments and communication with authors	managed reviewer assignments and communication with authors	-	-	NO
5780851	29363432	PH	2	managed reviewer assignments and communication with authors	managed reviewer assignments and communication with authors	-	-	NO
5780851	29363432	SR	2	wrote manuscript|managed reviewer assignments and communication with authors	wrote manuscript	Wrote the paper	Writing - Original Draft	YES
5780851	29363432	SR	2	wrote manuscript|managed reviewer assignments and communication with authors	managed reviewer assignments and communication with authors	-	-	NO
4641933	26605330	H. J. Beelen	2	also share equal contribution	also share equal contribution	-	-	NO
4641933	26605330	Marc G. Vervloet	2	also share equal contribution	also share equal contribution	-	-	NO
416569	15169560	JCS	2	contributed to the conceptualization of the study and analyses, and the writing of the manuscript	contributed to the conceptualization of the study and analyses, and the writing of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
416569	15169560	PMW	2	helped with the data analyses, interpretation, and the writing of the manuscript	helped with the data analyses, interpretation, and the writing of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
416569	15169560	RCP	2	helped conceptualize the study and the writing of the manuscript	helped conceptualize the study and the writing of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
416569	15169560	TRP	2	conducted the main study components, analyzed the data, and drafted the manuscript	conducted the main study components, analyzed the data, and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4418603	25938762	ADTB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418603	25938762	ADTB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418603	25938762	ADTB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418603	25938762	ADTB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418603	25938762	EH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418603	25938762	EH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418603	25938762	EH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418603	25938762	EH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418603	25938762	EH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418603	25938762	EI	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4418603	25938762	EI	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418603	25938762	GAC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4418603	25938762	GAC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418603	25938762	GNM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418603	25938762	GNM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418603	25938762	GNM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418603	25938762	GNM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418603	25938762	GNM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418603	25938762	LL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4418603	25938762	LL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418603	25938762	NB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418603	25938762	NB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418603	25938762	NB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418603	25938762	NB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418603	25938762	NB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418603	25938762	PRB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418603	25938762	PRB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418603	25938762	PRB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418603	25938762	PRB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418603	25938762	PRB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418603	25938762	VVS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418603	25938762	VVS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418603	25938762	VVS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418603	25938762	VVS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418603	25938762	VVS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270802	25247685	A.M.	1	Analysis of the experimental data	Analysis of the experimental data	Analyzed the data	Formal analysis	YES
6270802	25247685	A.T.	1	Analysis of the experimental data	Analysis of the experimental data	Analyzed the data	Formal analysis	YES
6270802	25247685	D.C.V.	1	Contributed to antimicrobial and antioxidant experiments|Analysis of the experimental data	Contributed to antimicrobial and antioxidant experiments	Performed the experiments	Investigation	YES
6270802	25247685	D.C.V.	1	Contributed to antimicrobial and antioxidant experiments|Analysis of the experimental data	Analysis of the experimental data	Analyzed the data	Formal analysis	YES
6270802	25247685	L.V.	1	Analysis of the experimental data	Analysis of the experimental data	Analyzed the data	Formal analysis	YES
6270802	25247685	O.R.	1	Contributed to antimicrobial and antioxidant experiments|Analysis of the experimental data	Contributed to antimicrobial and antioxidant experiments	Performed the experiments	Investigation	YES
6270802	25247685	O.R.	1	Contributed to antimicrobial and antioxidant experiments|Analysis of the experimental data	Analysis of the experimental data	Analyzed the data	Formal analysis	YES
1991594	17912366	CP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1991594	17912366	CP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1991594	17912366	CP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1991594	17912366	CP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1991594	17912366	DM	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1991594	17912366	DM	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1991594	17912366	JP	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1991594	17912366	JS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1991594	17912366	JS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1991594	17912366	NL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1991594	17912366	PS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1991594	17912366	PS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5820362	29503658	AB	2	contributed to expression analysis	contributed to expression analysis	Performed the experiments	Investigation	YES
5820362	29503658	AP	2	carried out all experiments	carried out all experiments	Performed the experiments	Investigation	YES
5820362	29503658	BP	2	contributed to confocal analysis	contributed to confocal analysis	-	-	NO
5820362	29503658	DA	2	designed the study concept, coordinated the research and supervised experiments, performed data analysis, and wrote the manuscript	designed the study concept, coordinated the research and supervised experiments, performed data analysis, and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Project administration|Supervision|Writing - Original Draft	YES
5820362	29503658	JT	2	performed bioinformatics analysis	performed bioinformatics analysis	Performed the experiments	Formal analysis|Investigation	YES
5820362	29503658	KK	2	was involved in yeast study, cloning and expression analysis	was involved in yeast study, cloning and expression analysis	Performed the experiments	Investigation	YES
5820362	29503658	LW	2	supervised yeast complementation assays	supervised yeast complementation assays	Performed the experiments	Investigation|Supervision	YES
5820362	29503658	MK	2	was involved in cloning, expression analysis and hydroponic experiments	was involved in cloning, expression analysis and hydroponic experiments	Performed the experiments	Investigation	YES
5820362	29503658	MP	2	was involved in bioinformatics analysis and hydroponic experiments	was involved in bioinformatics analysis and hydroponic experiments	-	Formal analysis	YES
3531605	23143987	AD	PLoS52	performed experiments	performed experiments	Performed the experiments	Investigation	YES
3531605	23143987	AV	PLoS52	provided technical and material support, and intellectual content	provided technical and material support, and intellectual content	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
3531605	23143987	CC	PLoS52	conceived and designed the experiments|performed experiments|analysed the data|drafted the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
3531605	23143987	CC	PLoS52	conceived and designed the experiments|performed experiments|analysed the data|drafted the manuscript	performed experiments	Performed the experiments	Investigation	YES
3531605	23143987	CC	PLoS52	conceived and designed the experiments|performed experiments|analysed the data|drafted the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
3531605	23143987	CC	PLoS52	conceived and designed the experiments|performed experiments|analysed the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
3531605	23143987	CH	PLoS52	performed experiments|analysed the data	performed experiments	Performed the experiments	Investigation	YES
3531605	23143987	CH	PLoS52	performed experiments|analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
3531605	23143987	JFK	PLoS52	acquired some of the data and provided technical support	acquired some of the data and provided technical support	Performed the experiments	Investigation	YES
3531605	23143987	JW	PLoS52	provided material support	provided material support	Contributed reagents/materials/analysis tools	Resources	YES
3531605	23143987	MWH	PLoS52	conceived and designed the experiments|analysed the data|drafted the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
3531605	23143987	MWH	PLoS52	conceived and designed the experiments|analysed the data|drafted the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
3531605	23143987	MWH	PLoS52	conceived and designed the experiments|analysed the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
3531605	23143987	SS	PLoS52	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5780852	29363425	YWW	2	conceived the project, developed and tested the pipeline, and wrote the manuscript	conceived the project, developed and tested the pipeline, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
4641942	26605334	The authors	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
4418604	25938440	D-XC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418604	25938440	D-XS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418604	25938440	D-XS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418604	25938440	FG	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418604	25938440	JX	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418604	25938440	X-DT	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418604	25938440	X-WD	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5869327	29589217	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5869327	29589217	B-XZ	2	conceived the rapid screening method|conducted the experiment|analyzed the results and wrote the manuscript	conceived the rapid screening method	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5869327	29589217	B-XZ	2	conceived the rapid screening method|conducted the experiment|analyzed the results and wrote the manuscript	conducted the experiment	Performed the experiments	Investigation	YES
5869327	29589217	B-XZ	2	conceived the rapid screening method|conducted the experiment|analyzed the results and wrote the manuscript	analyzed the results and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5869327	29589217	D-PZ	2	conducted the soil samplings	conducted the soil samplings	Performed the experiments	Investigation	YES
5869327	29589217	G-WZ	2	conducted the bacterial isolation and identification	conducted the bacterial isolation and identification	Performed the experiments	Investigation	YES
5869327	29589217	H-ZL	2	conducted the bacterial isolation and identification	conducted the bacterial isolation and identification	Performed the experiments	Investigation	YES
5869327	29589217	JP	2	analyzed the results and wrote the manuscript	analyzed the results and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5869327	29589217	KD	2	conducted the experiment	conducted the experiment	Performed the experiments	Investigation	YES
5869327	29589217	MI	2	conceived the rapid screening method|conducted the experiment	conceived the rapid screening method	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5869327	29589217	MI	2	conceived the rapid screening method|conducted the experiment	conducted the experiment	Performed the experiments	Investigation	YES
5869327	29589217	Q-FB	2	conducted the soil samplings	conducted the soil samplings	Performed the experiments	Investigation	YES
5869327	29589217	X-RY	2	conceived the project	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5869327	29589217	Y-GZ	2	conceived the project|analyzed the results and wrote the manuscript	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5869327	29589217	Y-GZ	2	conceived the project|analyzed the results and wrote the manuscript	analyzed the results and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
1991595	17912367	DW	PLoS5	Wrote the paper|Conceived and designed the mathematical models, analyzed the mathematical models	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1991595	17912367	DW	PLoS5	Wrote the paper|Conceived and designed the mathematical models, analyzed the mathematical models	Conceived and designed the mathematical models, analyzed the mathematical models	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
1991595	17912367	NK	PLoS5	Wrote the paper|Conceived and designed the mathematical models, analyzed the mathematical models	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1991595	17912367	NK	PLoS5	Wrote the paper|Conceived and designed the mathematical models, analyzed the mathematical models	Conceived and designed the mathematical models, analyzed the mathematical models	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
3683608	23549460	ARA	2	participation in immunization of rabbits, specific antiserum preparation, western blotting performing	participation in immunization of rabbits, specific antiserum preparation, western blotting performing	Performed the experiments	Investigation	YES
3683608	23549460	DVP	2	immunocytochemistry and microscopy work performing, participation in design and coordination of study	immunocytochemistry and microscopy work performing, participation in design and coordination of study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Project administration	YES
3683608	23549460	MGS	2	participation in immunization of rabbits, specific antiserum preparation, western blotting performing	participation in immunization of rabbits, specific antiserum preparation, western blotting performing	Performed the experiments	Investigation	YES
3683608	23549460	NLB	2	immunocytochemistry and microscopy work performing, participation in design and coordination of study	immunocytochemistry and microscopy work performing, participation in design and coordination of study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Project administration	YES
3683608	23549460	SB	2	dot blotting performing, assistance in transfection studies	dot blotting performing, assistance in transfection studies	Performed the experiments	Investigation	YES
419719	15169559	JS	2	participated in the content analysis, provided computer expertise, and drafted portions of the manuscript	participated in the content analysis, provided computer expertise, and drafted portions of the manuscript	Wrote the paper	Formal analysis|Writing - Original Draft	YES
419719	15169559	LL	2	conceived of the study, participated in its design and coordination, carried out the focus groups, participated in the content analysis and drafted the manuscript	conceived of the study, participated in its design and coordination, carried out the focus groups, participated in the content analysis and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Project administration|Writing - Original Draft	YES
419719	15169559	MC	2	participated in the content analysis and co-wrote the manuscript	participated in the content analysis and co-wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5820414	29503655	JG	7	conducted the experiments, developed and conducted root water uptake modeling and revised the manuscript	conducted the experiments, developed and conducted root water uptake modeling and revised the manuscript	Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5820414	29503655	MB	7	conducted the experiments, analyzed the data and wrote the manuscript	conducted the experiments, analyzed the data and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5820414	29503655	MS	7	set up the hyprop method, revisedthe manuscript and contributed to writing	set up the hyprop method, revisedthe manuscript and contributed to writing	Performed the experiments|Wrote the paper	Methodology|Writing - Original Draft|Writing - Review & Editing	YES
6270803	25415474	Huan-Lu Song	PLoS52	who also perfected the manuscript	who also perfected the manuscript	-	-	NO
6270803	25415474	Jian-Bin Liu	PLoS52	performed research including data analysis and interpretation, literature search, and wrote the manuscript	performed research including data analysis and interpretation, literature search, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6270803	25415474	Ting-Ting Zou	PLoS52	who also perfected the manuscript	who also perfected the manuscript	-	-	NO
6270803	25415474	Xiao-Sheng Liu	PLoS52	performed research including data analysis and interpretation, literature search, and wrote the manuscript	performed research including data analysis and interpretation, literature search, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6270803	25415474	Ye Liu	PLoS52	who also perfected the manuscript	who also perfected the manuscript	-	-	NO
6270803	25415474	Zheng-Mao Yang	PLoS52	contributed reagents/materials/analysis tools	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418605	25938412	AK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418605	25938412	JH	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418605	25938412	JT	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4418605	25938412	JT	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418605	25938412	KB	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418605	25938412	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418605	25938412	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418605	25938412	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418605	25938412	MH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418605	25938412	MK	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418605	25938412	MK	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418605	25938412	RA	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418605	25938412	RA	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418605	25938412	RV	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418605	25938412	TH	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418605	25938412	TH	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5311926	28138068	C.M.	2	designed and prepared the figures	designed and prepared the figures	Conceived and designed the experiments	Visualization	YES
5311926	28138068	M.V.R.	2	wrote the paper with contributions of all authors	wrote the paper with contributions of all authors	Wrote the paper	Writing - Original Draft	YES
5311926	28138068	N.F.	2	designed and prepared the figures	designed and prepared the figures	Conceived and designed the experiments	Visualization	YES
1991596	17912356	DH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1991596	17912356	DH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1991596	17912356	DH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1991596	17912356	HS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1991596	17912356	LE	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1991596	17912356	LE	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1991596	17912356	LE	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1991596	17912356	MA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1991596	17912356	MA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1991596	17912356	MA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1991596	17912356	MA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1991596	17912356	MA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5780853	29363420	All	2	authors participated in the audition and revision of the manuscript	authors participated in the audition and revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5780853	29363420	CCL	2	supervised the under the	supervised the under the	-	Supervision	YES
5780853	29363420	CHS	2	authors participated in the audition and revision of the manuscript	authors participated in the audition and revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5780853	29363420	HDH	2	supervised the under the	supervised the under the	-	Supervision	YES
5780853	29363420	JRL	2	authors participated in the audition and revision of the manuscript	authors participated in the audition and revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5780853	29363420	YCL	2	under the|performed the circrna detection and data collection	under the	-	-	NO
5780853	29363420	YCL	2	under the|performed the circrna detection and data collection	performed the circrna detection and data collection	Performed the experiments	Investigation	YES
5780853	29363420	YJC	2	authors participated in the audition and revision of the manuscript	authors participated in the audition and revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5874223	29594843	All	2	data generated or analyzed during this study are included in this published article and its additional information files	data generated or analyzed during this study are included in this published article and its additional information files	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5874223	29594843	All authors	2	participated in discussion of the experimental results|read and approved the final manuscript	participated in discussion of the experimental results	Performed the experiments	Investigation	YES
5874223	29594843	All authors	2	participated in discussion of the experimental results|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5874223	29594843	HJL	2	performed experiments, analyzed and interpreted data, and prepared figures and tables	performed experiments, analyzed and interpreted data, and prepared figures and tables	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
5874223	29594843	JHL	2	reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5874223	29594843	JPW	2	conceived and designed the study|wrote the manuscript|reviewed and edited the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5874223	29594843	JPW	2	conceived and designed the study|wrote the manuscript|reviewed and edited the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5874223	29594843	JPW	2	conceived and designed the study|wrote the manuscript|reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5874223	29594843	SLH	2	reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5874223	29594843	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5874223	29594843	WCH	2	performed experiments, analyzed and interpreted data, and prepared figures and tables	performed experiments, analyzed and interpreted data, and prepared figures and tables	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
5874223	29594843	ZWC	2	conceived and designed the study|wrote the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5874223	29594843	ZWC	2	conceived and designed the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3891537	24459426	Bela Molnar	2	are co-last authors in this paper	are co-last authors in this paper	-	-	NO
3891537	24459426	Ferenc Sipos	2	are co-first authors	are co-first authors	-	-	NO
3891537	24459426	Gyorgyi Muzes	2	are co-last authors in this paper	are co-last authors in this paper	-	-	NO
3891537	24459426	Istvan Furi	2	are co-first authors	are co-first authors	-	-	NO
4641943	26605337	Agostinho Antunes	PLoS52	contributed reagents/materials/analysis tools|critically revised the paper	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4641943	26605337	Agostinho Antunes	PLoS52	contributed reagents/materials/analysis tools|critically revised the paper	critically revised the paper	Wrote the paper	Writing - Review & Editing	YES
4641943	26605337	Deborah Galpert	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4641943	26605337	Evys Ancede-Gallardo	PLoS52	performed the experiments|contributed reagents/materials/analysis tools	performed the experiments	Performed the experiments	Investigation	YES
4641943	26605337	Evys Ancede-Gallardo	PLoS52	performed the experiments|contributed reagents/materials/analysis tools	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4641943	26605337	Francisco Herrera	PLoS52	analyzed the data|contributed reagents/materials/analysis tools|critically revised the paper	analyzed the data	Analyzed the data	Formal analysis	YES
4641943	26605337	Francisco Herrera	PLoS52	analyzed the data|contributed reagents/materials/analysis tools|critically revised the paper	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4641943	26605337	Francisco Herrera	PLoS52	analyzed the data|contributed reagents/materials/analysis tools|critically revised the paper	critically revised the paper	Wrote the paper	Writing - Review & Editing	YES
4641943	26605337	Guillermin Aguero-Chapin	PLoS52	conceived and designed the experiments|analyzed the data|wrote the paper|critically revised the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4641943	26605337	Guillermin Aguero-Chapin	PLoS52	conceived and designed the experiments|analyzed the data|wrote the paper|critically revised the paper	analyzed the data	Analyzed the data	Formal analysis	YES
4641943	26605337	Guillermin Aguero-Chapin	PLoS52	conceived and designed the experiments|analyzed the data|wrote the paper|critically revised the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4641943	26605337	Guillermin Aguero-Chapin	PLoS52	conceived and designed the experiments|analyzed the data|wrote the paper|critically revised the paper	critically revised the paper	Wrote the paper	Writing - Review & Editing	YES
3992881	24444032	S These	2	authors contributed equally	authors contributed equally	-	-	NO
4418606	25938416	BL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418606	25938416	BL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418606	25938416	BL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418606	25938416	JT	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4418606	25938416	JT	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418606	25938416	KH	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418606	25938416	WL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418606	25938416	XL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418606	25938416	XL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418606	25938416	XL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418606	25938416	XL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418606	25938416	XXZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418606	25938416	XXZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418606	25938416	XXZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418606	25938416	XXZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418606	25938416	YT	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418606	25938416	YW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418606	25938416	YW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418606	25938416	ZW	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
6270804	25271428	Fawaz Aldabbagh	2	conceived and obtained funding for the project and oversaw the research	conceived and obtained funding for the project and oversaw the research	Conceived and designed the experiments	Conceptualization|Funding acquisition|Supervision	YES
6270804	25271428	Ingrid Allart-Simon	2	performed experimental work	performed experimental work	Performed the experiments	Investigation	YES
6270804	25271428	Janos Sapi	2	conceived and obtained funding for the project and oversaw the research	conceived and obtained funding for the project and oversaw the research	Conceived and designed the experiments	Conceptualization|Funding acquisition|Supervision	YES
6270804	25271428	Michael Gurry	2	performed experimental work	performed experimental work	Performed the experiments	Investigation	YES
6270804	25271428	Patrick McArdle	2	performed x-ray crystallography	performed x-ray crystallography	Performed the experiments	Investigation	YES
6270804	25271428	Stephane Gerard	2	conceived and obtained funding for the project and oversaw the research	conceived and obtained funding for the project and oversaw the research	Conceived and designed the experiments	Conceptualization|Funding acquisition|Supervision	YES
4418607	25938669	AA	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418607	25938669	AA	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418607	25938669	BG	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418607	25938669	CP	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418607	25938669	HGS	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418607	25938669	HGS	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418607	25938669	JCS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418607	25938669	JCS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418607	25938669	LC	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418607	25938669	LC	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418607	25938669	MBV	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418607	25938669	MBV	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418607	25938669	MBV	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418607	25938669	MD	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5780854	29363423	HJ	PLoS52	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5780854	29363423	JP	PLoS52	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5780854	29363423	JS	PLoS52	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5780854	29363423	LC	PLoS52	conceived and designed the experiments|analyzed data|wrote this manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5780854	29363423	LC	PLoS52	conceived and designed the experiments|analyzed data|wrote this manuscript	analyzed data	Analyzed the data	Formal analysis	YES
5780854	29363423	LC	PLoS52	conceived and designed the experiments|analyzed data|wrote this manuscript	wrote this manuscript	Wrote the paper	Writing - Original Draft	YES
5780854	29363423	MZ	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5780854	29363423	YH	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5780854	29363423	YJ	PLoS52	analyzed data|wrote this manuscript	analyzed data	Analyzed the data	Formal analysis	YES
5780854	29363423	YJ	PLoS52	analyzed data|wrote this manuscript	wrote this manuscript	Wrote the paper	Writing - Original Draft	YES
1991597	17912370	EP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1991597	17912370	EP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1991597	17912370	EP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1991597	17912370	EP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1991597	17912370	GL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1991597	17912370	GL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1991597	17912370	GL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1991597	17912370	GL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1991597	17912370	GL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1991597	17912370	JN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1991597	17912370	JN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1991597	17912370	JN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1991597	17912370	JN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1991597	17912370	JT	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1991597	17912370	JT	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1991597	17912370	MB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1991597	17912370	MB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1991597	17912370	MB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1991597	17912370	SS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1991597	17912370	SS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1991597	17912370	SS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1991597	17912370	TB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1991597	17912370	TB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1991597	17912370	TB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1991597	17912370	TB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1991597	17912370	TB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1991597	17912370	TK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1991597	17912370	TK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1991597	17912370	TK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1991597	17912370	TK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5820536	29503657	HC	2	analyzed the research results and wrote the paper	analyzed the research results and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5820536	29503657	HH	2	participated in the assays of dark treatment	participated in the assays of dark treatment	Performed the experiments	Investigation	YES
5820536	29503657	JZ	2	conceived the research plans, guided the whole study, and modified the paper	conceived the research plans, guided the whole study, and modified the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Supervision|Writing - Review & Editing	YES
5820536	29503657	LL	2	performed most of the experiments and analyzed the data	performed most of the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5820536	29503657	SL	2	performed most of the experiments and analyzed the data	performed most of the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5874226	29594834	AM	2	drafted the manuscript and contributed to data analysis	drafted the manuscript and contributed to data analysis	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5874226	29594834	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5874226	29594834	FKM	2	were the main investigator, synthesized the nanocomposite	were the main investigator, synthesized the nanocomposite	Performed the experiments	Investigation	YES
5874226	29594834	MF	2	drafted the manuscript and contributed to data analysis	drafted the manuscript and contributed to data analysis	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5874226	29594834	NKH	2	were the main investigator, synthesized the nanocomposite	were the main investigator, synthesized the nanocomposite	Performed the experiments	Investigation	YES
3683611	23549463	all authors	2	contributed to this work and approved the final version of the paper	contributed to this work and approved the final version of the paper	-	-	NO
5312016	28193811	A.K.	2	outlined the overall idea of studying rod-based colour vision in amphibians|revised the manuscript and approved the final version	outlined the overall idea of studying rod-based colour vision in amphibians	Conceived and designed the experiments	Conceptualization	YES
5312016	28193811	A.K.	2	outlined the overall idea of studying rod-based colour vision in amphibians|revised the manuscript and approved the final version	revised the manuscript and approved the final version	Wrote the paper	Writing - Review & Editing	YES
5312016	28193811	All co-authors	2	revised the manuscript and approved the final version	revised the manuscript and approved the final version	Wrote the paper	Writing - Review & Editing	YES
5312016	28193811	C.A.M.Y.	2	outlined the overall idea of studying rod-based colour vision in amphibians	outlined the overall idea of studying rod-based colour vision in amphibians	Conceived and designed the experiments	Conceptualization	YES
5312016	28193811	K.D.	2	outlined the overall idea of studying rod-based colour vision in amphibians	outlined the overall idea of studying rod-based colour vision in amphibians	Conceived and designed the experiments	Conceptualization	YES
5312016	28193811	S.L.K.	2	revised the manuscript and approved the final version	revised the manuscript and approved the final version	Wrote the paper	Writing - Review & Editing	YES
5312016	28193811	S.M.K.	2	revised the manuscript and approved the final version	revised the manuscript and approved the final version	Wrote the paper	Writing - Review & Editing	YES
6270805	24979401	C.-Y.H.	PLoS52	conceived and designed research	conceived and designed research	Conceived and designed the experiments	Conceptualization|Methodology	YES
6270805	24979401	F.X.	PLoS52	performed research and analyzed the data	performed research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270805	24979401	G.W.	PLoS52	performed research and contributed materials	performed research and contributed materials	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
6270805	24979401	L.-H.T.	PLoS52	conceived and designed research|wrote the paper	conceived and designed research	Conceived and designed the experiments	Conceptualization|Methodology	YES
6270805	24979401	L.-H.T.	PLoS52	conceived and designed research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270805	24979401	R.-S.H.	PLoS52	performed research and analyzed the data	performed research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270805	24979401	S.-Z.H.	PLoS52	performed research and analyzed the data	performed research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270805	24979401	X.-W.Q.	PLoS52	conceived and designed research|wrote the paper	conceived and designed research	Conceived and designed the experiments	Conceptualization|Methodology	YES
6270805	24979401	X.-W.Q.	PLoS52	conceived and designed research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5820543	29503653	All of the authors	2	have read and approved the final manuscript	have read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
1991598	17912369	BH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1991598	17912369	BH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1991598	17912369	BH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1991598	17912369	DH	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1991598	17912369	DH	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1991598	17912369	EF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1991598	17912369	EF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1991598	17912369	EF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1991598	17912369	EF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1991598	17912369	EF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1991598	17912369	GH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1991598	17912369	GH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1991598	17912369	GH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1991598	17912369	GH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1991598	17912369	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1991598	17912369	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1991598	17912369	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1991598	17912369	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1991598	17912369	MP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5780855	29363426	CMZ	2	executed the experiments	executed the experiments	Performed the experiments	Investigation	YES
5780855	29363426	LNC	2	developed the methodology|revised the manuscript|supervised the work, made critical revisions of the paper, and approved the submission of the manuscript	developed the methodology	Performed the experiments	Methodology	YES
5780855	29363426	LNC	2	developed the methodology|revised the manuscript|supervised the work, made critical revisions of the paper, and approved the submission of the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5780855	29363426	LNC	2	developed the methodology|revised the manuscript|supervised the work, made critical revisions of the paper, and approved the submission of the manuscript	supervised the work, made critical revisions of the paper, and approved the submission of the manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
5780855	29363426	QQS	2	executed the experiments	executed the experiments	Performed the experiments	Investigation	YES
5780855	29363426	SWZ	2	revised the manuscript|supervised the work, made critical revisions of the paper, and approved the submission of the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5780855	29363426	SWZ	2	revised the manuscript|supervised the work, made critical revisions of the paper, and approved the submission of the manuscript	supervised the work, made critical revisions of the paper, and approved the submission of the manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
5780855	29363426	TZ	2	developed the methodology|wrote this paper|revised the manuscript	developed the methodology	Performed the experiments	Methodology	YES
5780855	29363426	TZ	2	developed the methodology|wrote this paper|revised the manuscript	wrote this paper	Wrote the paper	Writing - Original Draft	YES
5780855	29363426	TZ	2	developed the methodology|wrote this paper|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5780855	29363426	WFG	2	developed the methodology|executed the experiments|wrote this paper|revised the manuscript	developed the methodology	Performed the experiments	Methodology	YES
5780855	29363426	WFG	2	developed the methodology|executed the experiments|wrote this paper|revised the manuscript	executed the experiments	Performed the experiments	Investigation	YES
5780855	29363426	WFG	2	developed the methodology|executed the experiments|wrote this paper|revised the manuscript	wrote this paper	Wrote the paper	Writing - Original Draft	YES
5780855	29363426	WFG	2	developed the methodology|executed the experiments|wrote this paper|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
3683612	23549464	E.P.	2	equally contributed to the manuscript	equally contributed to the manuscript	-	-	NO
3683612	23549464	G.N.	2	equally contributed to the manuscript	equally contributed to the manuscript	-	-	NO
5878155	29603024	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5878155	29603024	HFW	PLoS52	performed the research	performed the research	Performed the experiments	Investigation	YES
5878155	29603024	HH	PLoS52	designed the experimental scheme|performed the research|wrote the paper	designed the experimental scheme	Conceived and designed the experiments	Methodology	YES
5878155	29603024	HH	PLoS52	designed the experimental scheme|performed the research|wrote the paper	performed the research	Performed the experiments	Investigation	YES
5878155	29603024	HH	PLoS52	designed the experimental scheme|performed the research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5878155	29603024	JYL	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5878155	29603024	LLM	PLoS52	performed the research	performed the research	Performed the experiments	Investigation	YES
5878155	29603024	RJZ	PLoS52	designed the experimental scheme|supervised the research|polished the paper	designed the experimental scheme	Conceived and designed the experiments	Methodology	YES
5878155	29603024	RJZ	PLoS52	designed the experimental scheme|supervised the research|polished the paper	supervised the research	-	Supervision	YES
5878155	29603024	RJZ	PLoS52	designed the experimental scheme|supervised the research|polished the paper	polished the paper	Wrote the paper	Writing - Review & Editing	YES
5878155	29603024	XFS	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5312023	28193818	D.T.	2	analysed the data and wrote the manuscript	analysed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5312023	28193818	L.S.	2	analysed the data and wrote the manuscript	analysed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5312023	28193818	P.A.-L.	2	analysed the data and wrote the manuscript	analysed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4418608	25938410	JMS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418608	25938410	JMS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418608	25938410	JMS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418608	25938410	JMS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418608	25938410	JMS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418608	25938410	MATR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418608	25938410	MATR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418608	25938410	MATR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418608	25938410	MATR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418608	25938410	MATR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418608	25938410	MTBB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418608	25938410	MTBB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418608	25938410	MTBB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418608	25938410	MTBB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418608	25938410	MTBB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270806	25347458	A. Al-Dhabi	2	wrote the manuscript, performed the experiments, and analyzed the data	wrote the manuscript, performed the experiments, and analyzed the data	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6270806	25347458	U. Park	2	designed the experiments and analyzed the data	designed the experiments and analyzed the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
3569637	23255322	BS	2	performed the mouse surgeries	performed the mouse surgeries	Performed the experiments	Investigation	YES
3569637	23255322	BrdU	2	pulsing of mice	pulsing of mice	-	-	NO
3569637	23255322	EM	2	established the hypotheses, designed the study, co-analysed data and wrote the paper	established the hypotheses, designed the study, co-analysed data and wrote the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3569637	23255322	GG	2	performed histology	performed histology	Performed the experiments	Investigation	YES
3569637	23255322	JS	2	performed histology and assisted with enzymatical dissociation of hearts	performed histology and assisted with enzymatical dissociation of hearts	Performed the experiments	Investigation	YES
3569637	23255322	KC	2	performed confocal imaging	performed confocal imaging	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
3569637	23255322	KM	2	established the hypotheses, designed the study, performed the experiments, analysed data and wrote the paper	established the hypotheses, designed the study, performed the experiments, analysed data and wrote the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
3569637	23255322	YZ	2	was involved in study design and co-analysed data	was involved in study design and co-analysed data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
3683613	23549465	EDF	2	immunohistochemical study	immunohistochemical study	Performed the experiments	Investigation	YES
3683613	23549465	GF	2	critical revision and final approval of the manuscript	critical revision and final approval of the manuscript	Wrote the paper	Writing - Review & Editing	YES
3683613	23549465	LA	2	clinical data acquisition	clinical data acquisition	Performed the experiments	Investigation	YES
3683613	23549465	LP	2	study design, manuscript writing, case selection, slide review	study design, manuscript writing, case selection, slide review	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft|Writing - Review & Editing	YES
3683613	23549465	MEC	2	statistical analysis	statistical analysis	Analyzed the data	Formal analysis	YES
3683613	23549465	SC	2	statistical analysis	statistical analysis	Analyzed the data	Formal analysis	YES
3683613	23549465	SS	2	study design, manuscript writing, case selection, slide review	study design, manuscript writing, case selection, slide review	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft|Writing - Review & Editing	YES
1991599	17912342	AD	PLoS5	Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Discussed the results	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1991599	17912342	AD	PLoS5	Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Discussed the results	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1991599	17912342	AD	PLoS5	Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Discussed the results	Discussed the results	-	-	NO
1991599	17912342	CL	PLoS5	Conceived and designed the experiments|Wrote the paper|Discussed the results	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1991599	17912342	CL	PLoS5	Conceived and designed the experiments|Wrote the paper|Discussed the results	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1991599	17912342	CL	PLoS5	Conceived and designed the experiments|Wrote the paper|Discussed the results	Discussed the results	-	-	NO
1991599	17912342	FM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1991599	17912342	FM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1991599	17912342	FM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1991599	17912342	JH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1991599	17912342	JH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1991599	17912342	JH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1991599	17912342	JH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1991599	17912342	JV	PLoS5	Contributed reagents/materials/analysis tools|Discussed the results	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1991599	17912342	JV	PLoS5	Contributed reagents/materials/analysis tools|Discussed the results	Discussed the results	-	-	NO
1991599	17912342	KS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1991599	17912342	KS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1991599	17912342	KS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1991599	17912342	SP	PLoS5	Performed the experiments|Discussed the results	Performed the experiments	Performed the experiments	Investigation	YES
1991599	17912342	SP	PLoS5	Performed the experiments|Discussed the results	Discussed the results	-	-	NO
1991599	17912342	TD	PLoS5	Contributed reagents/materials/analysis tools|Discussed the results|Critically read the manuscript and made substantial improvements	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1991599	17912342	TD	PLoS5	Contributed reagents/materials/analysis tools|Discussed the results|Critically read the manuscript and made substantial improvements	Discussed the results	-	-	NO
1991599	17912342	TD	PLoS5	Contributed reagents/materials/analysis tools|Discussed the results|Critically read the manuscript and made substantial improvements	Critically read the manuscript and made substantial improvements	-	-	NO
1991599	17912342	VL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1991599	17912342	VV	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418609	25938668	CJY	PLoS5	Analyzed the data|Revised and approved the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4418609	25938668	CJY	PLoS5	Analyzed the data|Revised and approved the manuscript	Revised and approved the manuscript	Wrote the paper	Writing - Review & Editing	YES
4418609	25938668	JYC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Interpreted data|Revised and approved the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418609	25938668	JYC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Interpreted data|Revised and approved the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4418609	25938668	JYC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Interpreted data|Revised and approved the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4418609	25938668	JYC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Interpreted data|Revised and approved the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418609	25938668	JYC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Interpreted data|Revised and approved the manuscript	Interpreted data	Analyzed the data	Formal analysis	YES
4418609	25938668	JYC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Interpreted data|Revised and approved the manuscript	Revised and approved the manuscript	Wrote the paper	Writing - Review & Editing	YES
4418609	25938668	PRH	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Interpreted data|Revised and approved the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418609	25938668	PRH	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Interpreted data|Revised and approved the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4418609	25938668	PRH	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Interpreted data|Revised and approved the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418609	25938668	PRH	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Interpreted data|Revised and approved the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418609	25938668	PRH	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Interpreted data|Revised and approved the manuscript	Interpreted data	Analyzed the data	Formal analysis	YES
4418609	25938668	PRH	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Interpreted data|Revised and approved the manuscript	Revised and approved the manuscript	Wrote the paper	Writing - Review & Editing	YES
4418609	25938668	TCC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Interpreted data|Revised and approved the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418609	25938668	TCC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Interpreted data|Revised and approved the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4418609	25938668	TCC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Interpreted data|Revised and approved the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418609	25938668	TCC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Interpreted data|Revised and approved the manuscript	Interpreted data	Analyzed the data	Formal analysis	YES
4418609	25938668	TCC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Interpreted data|Revised and approved the manuscript	Revised and approved the manuscript	Wrote the paper	Writing - Review & Editing	YES
4418609	25938668	WYC	PLoS5	Interpreted data|Revised and approved the manuscript	Interpreted data	Analyzed the data	Formal analysis	YES
4418609	25938668	WYC	PLoS5	Interpreted data|Revised and approved the manuscript	Revised and approved the manuscript	Wrote the paper	Writing - Review & Editing	YES
5821101	29503654	All authors	2	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5821101	29503654	JS	2	contributed critical components to the draft	contributed critical components to the draft	Wrote the paper	Writing - Original Draft	YES
5821101	29503654	JW	2	conceived the topic and outline and critically revised the manuscript	conceived the topic and outline and critically revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5821101	29503654	RK	2	prepared the manuscript draft	prepared the manuscript draft	Wrote the paper	Writing - Original Draft	YES
5821101	29503654	XY	2	contributed critical components to the draft	contributed critical components to the draft	Wrote the paper	Writing - Original Draft	YES
5781056	29363424	ABS	2	analyzed the outcomes of the benchmark predictors for comparison purposes	analyzed the outcomes of the benchmark predictors for comparison purposes	Analyzed the data	Formal analysis	YES
5781056	29363424	AD	2	extracted the structural and evolutionary information of proteins and improved the draft	extracted the structural and evolutionary information of proteins and improved the draft	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5781056	29363424	AS	2	conducted the classification part of the project and drafted the manuscript	conducted the classification part of the project and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5781056	29363424	GT	2	analyzed the outcomes of the benchmark predictors for comparison purposes	analyzed the outcomes of the benchmark predictors for comparison purposes	Analyzed the data	Formal analysis	YES
5781056	29363424	SPL	2	extracted the structural and evolutionary information of proteins and improved the draft	extracted the structural and evolutionary information of proteins and improved the draft	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5781056	29363424	TT	2	supervised the entire project	supervised the entire project	-	Supervision	YES
5781056	29363424	YL	2	conducted the classification part of the project and drafted the manuscript	conducted the classification part of the project and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5880792	29611000	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5880792	29611000	Both authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
6270807	25322283	C.-H.R.	2	participated in the design of the study data analyses and manuscript	participated in the design of the study data analyses and manuscript	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
6270807	25322283	G.-H.J.	2	finalized the experimental work, interpreted the results and prepared figures	finalized the experimental work, interpreted the results and prepared figures	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
6270807	25322283	G.-Y.K.	2	finalized the experimental work, interpreted the results and prepared figures	finalized the experimental work, interpreted the results and prepared figures	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
6270807	25322283	H.S.	2	suggested the research work and discussed the experimental data	suggested the research work and discussed the experimental data	Performed the experiments	Investigation	YES
6270807	25322283	I.-W.C.	2	participated in the design of the study data analyses and manuscript	participated in the design of the study data analyses and manuscript	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
6270807	25322283	J.-W.J.	2	finalized the experimental work, interpreted the results and prepared figures	finalized the experimental work, interpreted the results and prepared figures	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
6270807	25322283	J.K.	2	finalized the experimental work, interpreted the results and prepared figures	finalized the experimental work, interpreted the results and prepared figures	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
6270807	25322283	W.-J.K.	2	wrote the paper, edited and revised manuscript	wrote the paper, edited and revised manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6270807	25322283	Y.H.C.	2	suggested the research work and discussed the experimental data|wrote the paper, edited and revised manuscript	suggested the research work and discussed the experimental data	Performed the experiments	Investigation	YES
6270807	25322283	Y.H.C.	2	suggested the research work and discussed the experimental data|wrote the paper, edited and revised manuscript	wrote the paper, edited and revised manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3569638	23281308	AK	2	performed experiments|analysed data|planned studies|wrote the manuscript	performed experiments	Performed the experiments	Investigation	YES
3569638	23281308	AK	2	performed experiments|analysed data|planned studies|wrote the manuscript	analysed data	Analyzed the data	Formal analysis	YES
3569638	23281308	AK	2	performed experiments|analysed data|planned studies|wrote the manuscript	planned studies	Conceived and designed the experiments	Conceptualization	YES
3569638	23281308	AK	2	performed experiments|analysed data|planned studies|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3569638	23281308	AS	2	obtained clinical specimens|analysed data|planned studies|wrote the manuscript	obtained clinical specimens	Performed the experiments	Investigation	YES
3569638	23281308	AS	2	obtained clinical specimens|analysed data|planned studies|wrote the manuscript	analysed data	Analyzed the data	Formal analysis	YES
3569638	23281308	AS	2	obtained clinical specimens|analysed data|planned studies|wrote the manuscript	planned studies	Conceived and designed the experiments	Conceptualization	YES
3569638	23281308	AS	2	obtained clinical specimens|analysed data|planned studies|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3569638	23281308	EB	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
3569638	23281308	FD	2	obtained clinical specimens	obtained clinical specimens	Performed the experiments	Investigation	YES
3569638	23281308	GB	2	analysed data	analysed data	Analyzed the data	Formal analysis	YES
3569638	23281308	HS	2	analysed data|planned studies|wrote the manuscript	analysed data	Analyzed the data	Formal analysis	YES
3569638	23281308	HS	2	analysed data|planned studies|wrote the manuscript	planned studies	Conceived and designed the experiments	Conceptualization	YES
3569638	23281308	HS	2	analysed data|planned studies|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3569638	23281308	JAP	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
3569638	23281308	JWN	2	planned studies	planned studies	Conceived and designed the experiments	Conceptualization	YES
3569638	23281308	MA	2	analysed data	analysed data	Analyzed the data	Formal analysis	YES
3569638	23281308	MCM	2	analysed data	analysed data	Analyzed the data	Formal analysis	YES
3569638	23281308	RB	2	planned studies	planned studies	Conceived and designed the experiments	Conceptualization	YES
3569638	23281308	RF	2	planned studies	planned studies	Conceived and designed the experiments	Conceptualization	YES
3569638	23281308	RPS	2	planned studies	planned studies	Conceived and designed the experiments	Conceptualization	YES
3569638	23281308	SA	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
3569638	23281308	SK	2	obtained clinical specimens|analysed data|planned studies|wrote the manuscript	obtained clinical specimens	Performed the experiments	Investigation	YES
3569638	23281308	SK	2	obtained clinical specimens|analysed data|planned studies|wrote the manuscript	analysed data	Analyzed the data	Formal analysis	YES
3569638	23281308	SK	2	obtained clinical specimens|analysed data|planned studies|wrote the manuscript	planned studies	Conceived and designed the experiments	Conceptualization	YES
3569638	23281308	SK	2	obtained clinical specimens|analysed data|planned studies|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3569638	23281308	SL	2	analysed data	analysed data	Analyzed the data	Formal analysis	YES
3569638	23281308	YHL	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
3683614	23549466	CLB	2	data acquisition and analysis	data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3683614	23549466	EICB	2	study concept and design contribution, data interpretation, critical revision of the manuscript, final approval of the materials and manuscript	study concept and design contribution, data interpretation, critical revision of the manuscript, final approval of the materials and manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Methodology|Resources|Writing - Review & Editing	YES
3683614	23549466	JLV	2	study design, data acquisition, analysis, and interpretation, manuscript drafting	study design, data acquisition, analysis, and interpretation, manuscript drafting	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
3683614	23549466	MJBMR	2	study concept and design contribution, data interpretation, critical revision of the manuscript, final approval of the materials and manuscript	study concept and design contribution, data interpretation, critical revision of the manuscript, final approval of the materials and manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Methodology|Resources|Writing - Review & Editing	YES
3683614	23549466	SAF	2	study design, data acquisition, analysis, and interpretation, manuscript drafting	study design, data acquisition, analysis, and interpretation, manuscript drafting	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5332863	28242738	L.G.	2	wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
5332863	28242738	R.J.K.	2	wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
5332863	28242738	Z.M.H.	2	wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
1991600	17912360	AN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1991600	17912360	AN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1991600	17912360	AN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1991600	17912360	AN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1991600	17912360	SG	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1991600	17912360	SG	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1991600	17912360	XW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1991600	17912360	XW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1991600	17912360	XW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418610	25938238	AQL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418610	25938238	AQL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418610	25938238	AQL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418610	25938238	AQL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418610	25938238	BHY	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418610	25938238	ML	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418610	25938238	RHS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418610	25938238	SLZ	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4418610	25938238	SLZ	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418610	25938238	WTY	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418610	25938238	WTY	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418610	25938238	YX	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5824616	29491868	BK	7	manuscript writing and discussion of results	manuscript writing and discussion of results	Wrote the paper	Writing - Original Draft	YES
5824616	29491868	CT	7	experimental and field design, discussion of results	experimental and field design, discussion of results	Conceived and designed the experiments	Methodology	YES
5824616	29491868	GS	7	conducted field experiments and statistical analysis	conducted field experiments and statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4644536	26609525	Xiuwen Yi	2	contributed equally to this work	contributed equally to this work	-	-	NO
4644536	26609525	Yirong Cai	2	contributed equally to this work|helped collect the data of the study and do the analysis in detail	contributed equally to this work	-	-	NO
4644536	26609525	Yirong Cai	2	contributed equally to this work|helped collect the data of the study and do the analysis in detail	helped collect the data of the study and do the analysis in detail	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5880795	29611040	All	PLoS52	data are shown in figures and tables within this article	data are shown in figures and tables within this article	-	Visualization	YES
5880795	29611040	All authors	PLoS52	reviewed the manuscript|read and approved the final manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5880795	29611040	All authors	PLoS52	reviewed the manuscript|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5880795	29611040	H Mayo	PLoS52	for critical reading and editing of our manuscript	for critical reading and editing of our manuscript	Wrote the paper	Writing - Review & Editing	YES
5880795	29611040	HYB	PLoS52	conceived and designed the research|analyzed the data|wrote and edited the manuscript	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5880795	29611040	HYB	PLoS52	conceived and designed the research|analyzed the data|wrote and edited the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5880795	29611040	HYB	PLoS52	conceived and designed the research|analyzed the data|wrote and edited the manuscript	wrote and edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5880795	29611040	The authors	PLoS52	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5880795	29611040	YXC	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5880795	29611040	ZH	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5880795	29611040	ZYF	PLoS52	conceived and designed the research|wrote and edited the manuscript	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5880795	29611040	ZYF	PLoS52	conceived and designed the research|wrote and edited the manuscript	wrote and edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6270808	24731986	C.M.	2	participated in design and coordination of the study and drafted manuscript	participated in design and coordination of the study and drafted manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft	YES
6270808	24731986	C.T.	2	participated in design and coordination of the study and drafted manuscript	participated in design and coordination of the study and drafted manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft	YES
6270808	24731986	D.P.	2	participated in design and coordination of the study and drafted manuscript	participated in design and coordination of the study and drafted manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft	YES
6270808	24731986	E.D.P.	2	participated in design and coordination of the study and drafted manuscript	participated in design and coordination of the study and drafted manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft	YES
6270808	24731986	E.H.	2	participated in design and coordination of the study and drafted manuscript	participated in design and coordination of the study and drafted manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft	YES
6270808	24731986	F.F.	2	participated in design and coordination of the study and drafted manuscript	participated in design and coordination of the study and drafted manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft	YES
6270808	24731986	J.-F.F.	2	participated in design and coordination of the study and drafted manuscript	participated in design and coordination of the study and drafted manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft	YES
6270808	24731986	J.B.	2	coordinated the culture and collection of termite samples|participated in design and coordination of the study and drafted manuscript	coordinated the culture and collection of termite samples	Performed the experiments	Investigation|Project administration	YES
6270808	24731986	J.B.	2	coordinated the culture and collection of termite samples|participated in design and coordination of the study and drafted manuscript	participated in design and coordination of the study and drafted manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft	YES
6270808	24731986	J.D.	2	participated in design and coordination of the study and drafted manuscript	participated in design and coordination of the study and drafted manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft	YES
6270808	24731986	M.V.	2	participated in design and coordination of the study and drafted manuscript	participated in design and coordination of the study and drafted manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft	YES
6270808	24731986	P.T.	2	participated in design and coordination of the study and drafted manuscript	participated in design and coordination of the study and drafted manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft	YES
3569639	23255347	AF	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
3569639	23255347	AK	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
3569639	23255347	FT	PLoS52	obtained the patient autopsy samples and performed neuropathological and clinical diagnosis|provided critical inputs for the manuscript	obtained the patient autopsy samples and performed neuropathological and clinical diagnosis	Performed the experiments	Investigation	YES
3569639	23255347	FT	PLoS52	obtained the patient autopsy samples and performed neuropathological and clinical diagnosis|provided critical inputs for the manuscript	provided critical inputs for the manuscript	-	-	NO
3569639	23255347	GS	PLoS52	obtained the patient autopsy samples and performed neuropathological and clinical diagnosis|provided critical inputs for the manuscript	obtained the patient autopsy samples and performed neuropathological and clinical diagnosis	Performed the experiments	Investigation	YES
3569639	23255347	GS	PLoS52	obtained the patient autopsy samples and performed neuropathological and clinical diagnosis|provided critical inputs for the manuscript	provided critical inputs for the manuscript	-	-	NO
3569639	23255347	HA	PLoS52	obtained the patient autopsy samples and performed neuropathological and clinical diagnosis	obtained the patient autopsy samples and performed neuropathological and clinical diagnosis	Performed the experiments	Investigation	YES
3569639	23255347	HH	PLoS52	obtained the patient autopsy samples and performed neuropathological and clinical diagnosis|advised the staining of human sample	obtained the patient autopsy samples and performed neuropathological and clinical diagnosis	Performed the experiments	Investigation	YES
3569639	23255347	HH	PLoS52	obtained the patient autopsy samples and performed neuropathological and clinical diagnosis|advised the staining of human sample	advised the staining of human sample	Performed the experiments	Investigation	YES
3569639	23255347	HT	PLoS52	designed the study|performed the experiments|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
3569639	23255347	HT	PLoS52	designed the study|performed the experiments|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
3569639	23255347	HT	PLoS52	designed the study|performed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3569639	23255347	KY	PLoS52	designed the study|provided inputs to analysis|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
3569639	23255347	KY	PLoS52	designed the study|provided inputs to analysis|wrote the manuscript	provided inputs to analysis	-	-	NO
3569639	23255347	KY	PLoS52	designed the study|provided inputs to analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3569639	23255347	NA	PLoS52	obtained the patient autopsy samples and performed neuropathological and clinical diagnosis|provided critical inputs for the manuscript	obtained the patient autopsy samples and performed neuropathological and clinical diagnosis	Performed the experiments	Investigation	YES
3569639	23255347	NA	PLoS52	obtained the patient autopsy samples and performed neuropathological and clinical diagnosis|provided critical inputs for the manuscript	provided critical inputs for the manuscript	-	-	NO
3569639	23255347	SM	PLoS52	obtained the patient autopsy samples and performed neuropathological and clinical diagnosis|advised the staining of human sample	obtained the patient autopsy samples and performed neuropathological and clinical diagnosis	Performed the experiments	Investigation	YES
3569639	23255347	SM	PLoS52	obtained the patient autopsy samples and performed neuropathological and clinical diagnosis|advised the staining of human sample	advised the staining of human sample	Performed the experiments	Investigation	YES
3569639	23255347	YH	PLoS52	obtained the patient autopsy samples and performed neuropathological and clinical diagnosis	obtained the patient autopsy samples and performed neuropathological and clinical diagnosis	Performed the experiments	Investigation	YES
3569639	23255347	YI	PLoS52	performed the experiments|obtained the patient autopsy samples and performed neuropathological and clinical diagnosis|provided critical inputs for the manuscript	performed the experiments	Performed the experiments	Investigation	YES
3569639	23255347	YI	PLoS52	performed the experiments|obtained the patient autopsy samples and performed neuropathological and clinical diagnosis|provided critical inputs for the manuscript	obtained the patient autopsy samples and performed neuropathological and clinical diagnosis	Performed the experiments	Investigation	YES
3569639	23255347	YI	PLoS52	performed the experiments|obtained the patient autopsy samples and performed neuropathological and clinical diagnosis|provided critical inputs for the manuscript	provided critical inputs for the manuscript	-	-	NO
5781308	29361906	HVP	2	performed experiments, analyzed data and wrote the paper	performed experiments, analyzed data and wrote the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5781308	29361906	MWY	2	designed, performed the experiments, analyzed data and wrote the paper	designed, performed the experiments, analyzed data and wrote the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4644537	26609524	LiC	2	contributed equally to this work	contributed equally to this work	-	-	NO
4644537	26609524	Wei Zhang	2	contributed equally to this work	contributed equally to this work	-	-	NO
4418611	25938486	AP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418611	25938486	CA	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418611	25938486	CF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418611	25938486	CF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418611	25938486	CF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418611	25938486	CM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418611	25938486	FDR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418611	25938486	FDR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418611	25938486	FDR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418611	25938486	GDP	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418611	25938486	LF	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418611	25938486	RC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418611	25938486	SC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418611	25938486	SC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418611	25938486	SC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418611	25938486	SC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418611	25938486	SR	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1991621	17912371	TL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1991621	17912371	TL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1991621	17912371	TL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1991621	17912371	TL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5825912	29515605	AR	PLoS52	provided the editorial advice	provided the editorial advice	-	-	NO
5825912	29515605	EP	PLoS52	conceived and designed the experiments|performed the experiments and analyzed the data|wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5825912	29515605	EP	PLoS52	conceived and designed the experiments|performed the experiments and analyzed the data|wrote the manuscript	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5825912	29515605	EP	PLoS52	conceived and designed the experiments|performed the experiments and analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5825912	29515605	MA	PLoS52	conceived and designed the experiments|performed the experiments and analyzed the data|wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5825912	29515605	MA	PLoS52	conceived and designed the experiments|performed the experiments and analyzed the data|wrote the manuscript	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5825912	29515605	MA	PLoS52	conceived and designed the experiments|performed the experiments and analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5825912	29515605	MS	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5825912	29515605	NB	PLoS52	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5825912	29515605	RS	PLoS52	conceived and designed the experiments|performed the experiments and analyzed the data	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5825912	29515605	RS	PLoS52	conceived and designed the experiments|performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270809	24950442	All authors	2	discussed the results and implications, and commented on the manuscript at all stages	discussed the results and implications, and commented on the manuscript at all stages	-	-	NO
6270809	24950442	Galina Kurlyandskaya	2	wrote the first version of the manuscript, prepared the samples for magnetic measurements, performed the measurements and interpreted the data	wrote the first version of the manuscript, prepared the samples for magnetic measurements, performed the measurements and interpreted the data	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6270809	24950442	Juan Carlos Aphesteguy	2	wrote the first version of the manuscript, prepared the samples for magnetic measurements, performed the measurements and interpreted the data	wrote the first version of the manuscript, prepared the samples for magnetic measurements, performed the measurements and interpreted the data	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6270809	24950442	Juan Carlos Carlos	2	fabricated the nanoparticles	fabricated the nanoparticles	Performed the experiments	Investigation	YES
6270809	24950442	Silvia Elena Jacobo	2	fabricated the nanoparticles	fabricated the nanoparticles	Performed the experiments	Investigation	YES
5782384	29361907	AH	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5782384	29361907	AH	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
5782384	29361907	AH	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5782384	29361907	DW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5782384	29361907	DW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
5782384	29361907	DW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5782384	29361907	DW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5782384	29361907	JP	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5782384	29361907	JP	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
5782384	29361907	JP	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5782384	29361907	MJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5782384	29361907	MJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
5782384	29361907	MJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5782384	29361907	MJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5782384	29361907	PJ	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5782384	29361907	PJ	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5782384	29361907	RH	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5782384	29361907	RH	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
5782384	29361907	RH	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5352810	28289251	A.J.W.	2	made notes on the group discussions that were the basis for the review	made notes on the group discussions that were the basis for the review	-	-	NO
5352810	28289251	All authors	2	contributed ideas and substantive written sections to the review	contributed ideas and substantive written sections to the review	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
5352810	28289251	J.A.	2	made notes on the group discussions that were the basis for the review	made notes on the group discussions that were the basis for the review	-	-	NO
5880796	29610998	AL	2	participated in the drafting and reviewing of the manuscript, analyzed the data and contributed to the statistical analysis	participated in the drafting and reviewing of the manuscript, analyzed the data and contributed to the statistical analysis	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5880796	29610998	AW	2	participated in the fish culture experiments	participated in the fish culture experiments	Performed the experiments	Investigation	YES
5880796	29610998	All	2	data are fully available without restriction|applicable international, national, and institutional guidelines for the care and use of animals were followed	data are fully available without restriction	-	-	NO
5880796	29610998	All	2	data are fully available without restriction|applicable international, national, and institutional guidelines for the care and use of animals were followed	applicable international, national, and institutional guidelines for the care and use of animals were followed	-	-	NO
5880796	29610998	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5880796	29610998	HS	2	participated in the drafting and reviewing of the manuscript, analyzed the data and contributed to the statistical analysis	participated in the drafting and reviewing of the manuscript, analyzed the data and contributed to the statistical analysis	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5880796	29610998	JS	2	supervised and provided important intellectual content for the research design, coordinated the study and contributed to the drafting of the manuscript	supervised and provided important intellectual content for the research design, coordinated the study and contributed to the drafting of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Supervision|Writing - Original Draft	YES
5880796	29610998	KX	2	participated in the fish culture experiments	participated in the fish culture experiments	Performed the experiments	Investigation	YES
5880796	29610998	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5880796	29610998	XH	2	participated in the fish culture experiments	participated in the fish culture experiments	Performed the experiments	Investigation	YES
5880796	29610998	XS	2	participated in the drafting and reviewing of the manuscript, analyzed the data and contributed to the statistical analysis	participated in the drafting and reviewing of the manuscript, analyzed the data and contributed to the statistical analysis	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5880796	29610998	YS	2	participated in the drafting and reviewing of the manuscript, analyzed the data and contributed to the statistical analysis	participated in the drafting and reviewing of the manuscript, analyzed the data and contributed to the statistical analysis	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5880796	29610998	ZH	2	performed all measurements and experiments and drafted the manuscript	performed all measurements and experiments and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4418613	25938505	CMP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418613	25938505	CMP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418613	25938505	CMP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418613	25938505	CMP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418613	25938505	CMP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418613	25938505	JHL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418613	25938505	JHL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418613	25938505	JHL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418613	25938505	JMG	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418613	25938505	JSB	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418613	25938505	JSB	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418613	25938505	SJP	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418613	25938505	SJP	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418613	25938505	SML	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3683616	23549468	DF	2	evaluation of results and discussion	evaluation of results and discussion	-	-	NO
3683616	23549468	EB	2	helping in technical part	helping in technical part	-	-	NO
3683616	23549468	EDN	2	collection of samples, processing, sectioning and immunohistochemical part of the work|evaluation of results and discussion|work design, results discussion and manuscript writing	collection of samples, processing, sectioning and immunohistochemical part of the work	Performed the experiments	Data curation|Investigation	YES
3683616	23549468	EDN	2	collection of samples, processing, sectioning and immunohistochemical part of the work|evaluation of results and discussion|work design, results discussion and manuscript writing	evaluation of results and discussion	-	-	NO
3683616	23549468	EDN	2	collection of samples, processing, sectioning and immunohistochemical part of the work|evaluation of results and discussion|work design, results discussion and manuscript writing	work design, results discussion and manuscript writing	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
3683616	23549468	MDP	2	helping in technical part	helping in technical part	-	-	NO
3683616	23549468	MP	2	work design, results discussion and manuscript writing	work design, results discussion and manuscript writing	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
3683616	23549468	PM-S	2	helping in technical part	helping in technical part	-	-	NO
3569640	23165896	AA	7	acquisition of data, analyses and interpretation of data	acquisition of data, analyses and interpretation of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3569640	23165896	AB	7	acquisition of data, analyses and interpretation of data, manuscript preparation	acquisition of data, analyses and interpretation of data, manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3569640	23165896	CC	7	acquisition of data, manuscript preparation, statistical analyses	acquisition of data, manuscript preparation, statistical analyses	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3569640	23165896	DML	7	study conception, analyses and interpretation of data, manuscript preparation	study conception, analyses and interpretation of data, manuscript preparation	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
3569640	23165896	EB	7	study conception, study design, acquisition of data, analyses and interpretation of data, manuscript preparation	study conception, study design, acquisition of data, analyses and interpretation of data, manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
3569640	23165896	LHB	7	study design, acquisition of data, analyses and interpretation of data, manuscript preparation, statistical analyses	study design, acquisition of data, analyses and interpretation of data, manuscript preparation, statistical analyses	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
3569640	23165896	LL	7	acquisition of data, manuscript preparation, statistical analyses	acquisition of data, manuscript preparation, statistical analyses	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3569640	23165896	NC	7	study conception, study design, acquisition of data, analyses and interpretation of data, manuscript preparation, statistical analyses	study conception, study design, acquisition of data, analyses and interpretation of data, manuscript preparation, statistical analyses	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
3569640	23165896	PAN	7	contributed critical reagent, analyses and interpretation of data, manuscript preparation	contributed critical reagent, analyses and interpretation of data, manuscript preparation	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
3569640	23165896	RG	7	interpretation of data, manuscript preparation	interpretation of data, manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3569640	23165896	RSh	7	acquisition of data, analyses and interpretation of data	acquisition of data, analyses and interpretation of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3569640	23165896	RSu	7	acquisition of data, manuscript preparation, statistical analyses	acquisition of data, manuscript preparation, statistical analyses	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3569640	23165896	RWF	7	generated critical reagent, manuscript preparation	generated critical reagent, manuscript preparation	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3569640	23165896	ST	7	acquisition of data, analyses and interpretation of data, manuscript preparation	acquisition of data, analyses and interpretation of data, manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3569640	23165896	WHR	7	analyses and interpretation of data, manuscript preparation	analyses and interpretation of data, manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
1991622	17912353	BT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1991622	17912353	BT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1991622	17912353	BT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1991622	17912353	BT	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1991622	17912353	CC	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1991622	17912353	CC	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1991622	17912353	ER	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1991622	17912353	ER	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1991622	17912353	JS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1991622	17912353	JS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1991622	17912353	JS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1991622	17912353	KR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1991622	17912353	KR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1991622	17912353	KR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1991622	17912353	KR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1991622	17912353	PB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1991622	17912353	PB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1991622	17912353	PB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1991622	17912353	PB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1991622	17912353	RB	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1991622	17912353	RB	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1991622	17912353	SP	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1991622	17912353	SP	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5825913	29515606	DE	2	supervised sequencing-data analysis	supervised sequencing-data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Supervision	YES
5825913	29515606	JB	2	contributed to sequencing	contributed to sequencing	Performed the experiments	Investigation	YES
5825913	29515606	JP	2	contributed to phenotyping	contributed to phenotyping	Performed the experiments	Investigation	YES
5825913	29515606	KS	2	contributed to phenotyping	contributed to phenotyping	Performed the experiments	Investigation	YES
5825913	29515606	PR	2	analyzed the sequencing data	analyzed the sequencing data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5825913	29515606	TC	2	contributed to phenotyping	contributed to phenotyping	Performed the experiments	Investigation	YES
5825913	29515606	TK	2	contributed to phenotyping	contributed to phenotyping	Performed the experiments	Investigation	YES
5825913	29515606	TS	2	conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5825913	29515606	YL	2	conceived the study|performed the gwas and gs analysis|wrote the manuscript and all the authors read and approved the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5825913	29515606	YL	2	conceived the study|performed the gwas and gs analysis|wrote the manuscript and all the authors read and approved the manuscript	performed the gwas and gs analysis	Performed the experiments	Investigation	YES
5825913	29515606	YL	2	conceived the study|performed the gwas and gs analysis|wrote the manuscript and all the authors read and approved the manuscript	wrote the manuscript and all the authors read and approved the manuscript	Wrote the paper	Writing - Original Draft	YES
4418615	25938436	AA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418615	25938436	AA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418615	25938436	AA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418615	25938436	AA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418615	25938436	CJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418615	25938436	CJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418615	25938436	CJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418615	25938436	CJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418615	25938436	CJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418615	25938436	SN	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418615	25938436	SN	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5782385	29361913	GZZ	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5782385	29361913	WZG	2	drafted the manuscript|revised the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5782385	29361913	WZG	2	drafted the manuscript|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5352811	28289252	A.F.	2	coordinated the transmission research retreat that led to this special issue, contributed to the original discussions and played a substantial role in writing and editing the paper	coordinated the transmission research retreat that led to this special issue, contributed to the original discussions and played a substantial role in writing and editing the paper	Wrote the paper	Project administration|Writing - Original Draft|Writing - Review & Editing	YES
5352811	28289252	All authors	2	contributed to discussions and made substantial contributions to writing sections of the manuscript and reviewing the manuscript prior to submission	contributed to discussions and made substantial contributions to writing sections of the manuscript and reviewing the manuscript prior to submission	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5352811	28289252	H.M.	2	led discussions and coordinated initial writing of the paper	led discussions and coordinated initial writing of the paper	Wrote the paper	Project administration|Writing - Original Draft	YES
5352811	28289252	J.L.	2	coordinated the transmission research retreat that led to this special issue, contributed to the original discussions and played a substantial role in writing and editing the paper	coordinated the transmission research retreat that led to this special issue, contributed to the original discussions and played a substantial role in writing and editing the paper	Wrote the paper	Project administration|Writing - Original Draft|Writing - Review & Editing	YES
5882472	29616370	All authors	2	reviewed the final version of the manuscript|read and approved the final manuscript	reviewed the final version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5882472	29616370	All authors	2	reviewed the final version of the manuscript|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5882472	29616370	GB	2	developed the study design|wrote the manuscript	developed the study design	Conceived and designed the experiments	Methodology	YES
5882472	29616370	GB	2	developed the study design|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5882472	29616370	MS	2	performed the laboratory experiments and the statistical analyses|evaluated the obtained data and visualized all results|wrote the manuscript	performed the laboratory experiments and the statistical analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5882472	29616370	MS	2	performed the laboratory experiments and the statistical analyses|evaluated the obtained data and visualized all results|wrote the manuscript	evaluated the obtained data and visualized all results	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
5882472	29616370	MS	2	performed the laboratory experiments and the statistical analyses|evaluated the obtained data and visualized all results|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5882472	29616370	SL	2	developed the study design|optimized the process of combined alkylpyrazine/maltodextrin treatments	developed the study design	Conceived and designed the experiments	Methodology	YES
5882472	29616370	SL	2	developed the study design|optimized the process of combined alkylpyrazine/maltodextrin treatments	optimized the process of combined alkylpyrazine/maltodextrin treatments	-	-	NO
5882472	29616370	TC	2	developed the study design|evaluated the obtained data and visualized all results|wrote the manuscript	developed the study design	Conceived and designed the experiments	Methodology	YES
5882472	29616370	TC	2	developed the study design|evaluated the obtained data and visualized all results|wrote the manuscript	evaluated the obtained data and visualized all results	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
5882472	29616370	TC	2	developed the study design|evaluated the obtained data and visualized all results|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6270810	24603555	Cesar Morales-Verdejo	2	collected and processed data	collected and processed data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
6270810	24603555	David Pessoa-Mahana	2	collected and processed data	collected and processed data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
6270810	24603555	Jaime Mella-Raipan	2	participated in designing the study|conducted the study	participated in designing the study	Conceived and designed the experiments	Methodology	YES
6270810	24603555	Jaime Mella-Raipan	2	participated in designing the study|conducted the study	conducted the study	Performed the experiments	Investigation	YES
6270810	24603555	Santiago Hernandez-Pino	2	participated in designing the study	participated in designing the study	Conceived and designed the experiments	Methodology	YES
1991623	17912362	SG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1991623	17912362	SG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1991623	17912362	SG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1991623	17912362	SG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1991623	17912362	SG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5825990	29515596	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4418617	25938560	AMR	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418617	25938560	FG	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418617	25938560	FG	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418617	25938560	FG	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418617	25938560	HD	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418617	25938560	JG	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418617	25938560	JY	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418617	25938560	JY	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418617	25938560	JY	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418617	25938560	MJK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418617	25938560	MJK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418617	25938560	MJK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418617	25938560	RJM	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418617	25938560	WJ	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418617	25938560	WJ	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418617	25938560	XY	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418617	25938560	ZH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
3569641	23255300	AG	2	contributed to some animal experiments and mosquitoes dissection	contributed to some animal experiments and mosquitoes dissection	Performed the experiments	Investigation	YES
3569641	23255300	All authors	2	commented and corrected the manuscript	commented and corrected the manuscript	Wrote the paper	Writing - Review & Editing	YES
3569641	23255300	JFF	2	also contributed to experiments and supervised insectarium activity	also contributed to experiments and supervised insectarium activity	Performed the experiments	Investigation|Supervision	YES
3569641	23255300	MO	2	designed experiments and performed most of the experiments	designed experiments and performed most of the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3569641	23255300	MT	2	contributed to some animal experiments and mosquitoes dissection|contributed to insectarium activity	contributed to some animal experiments and mosquitoes dissection	Performed the experiments	Investigation	YES
3569641	23255300	MT	2	contributed to some animal experiments and mosquitoes dissection|contributed to insectarium activity	contributed to insectarium activity	-	-	NO
5352812	28289253	A.J.W.	2	conceived the review and coordinated the writing of the paper	conceived the review and coordinated the writing of the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Project administration|Writing - Original Draft|Writing - Review & Editing	YES
5352812	28289253	All authors	2	contributed proposals for definitions of vector and made substantial contributions to writing sections of the manuscript and reviewing the entire manuscript prior to submission	contributed proposals for definitions of vector and made substantial contributions to writing sections of the manuscript and reviewing the entire manuscript prior to submission	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5784534	29370758	AHG	2	constructed the d dtxr mutant|performed the cultivation and rna isolation	constructed the d dtxr mutant	Performed the experiments	Investigation	YES
5784534	29370758	AHG	2	constructed the d dtxr mutant|performed the cultivation and rna isolation	performed the cultivation and rna isolation	Performed the experiments	Investigation	YES
5784534	29370758	AT	2	coordinated the study and participated in data analysis	coordinated the study and participated in data analysis	Analyzed the data	Formal analysis|Project administration	YES
5784534	29370758	HTT	2	coordinated the study and participated in data analysis	coordinated the study and participated in data analysis	Analyzed the data	Formal analysis|Project administration	YES
5784534	29370758	JHL	2	performed the cultivation and rna isolation	performed the cultivation and rna isolation	Performed the experiments	Investigation	YES
5784534	29370758	JK	2	coordinated the study and participated in data analysis	coordinated the study and participated in data analysis	Analyzed the data	Formal analysis|Project administration	YES
5784534	29370758	MW	2	created the whole transcriptome cdna libraries, conducted all bioinformatic analyses and drafted the manuscript|prepared the primary 5-end cdna library	created the whole transcriptome cdna libraries, conducted all bioinformatic analyses and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5784534	29370758	MW	2	created the whole transcriptome cdna libraries, conducted all bioinformatic analyses and drafted the manuscript|prepared the primary 5-end cdna library	prepared the primary 5-end cdna library	Performed the experiments	Investigation	YES
5784534	29370758	TB	2	prepared the primary 5-end cdna library	prepared the primary 5-end cdna library	Performed the experiments	Investigation	YES
4418632	25938910	DTC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418632	25938910	DTC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418632	25938910	DTC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418632	25938910	DTC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418632	25938910	JAC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418632	25938910	JAC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418632	25938910	JAC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418632	25938910	JAC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418632	25938910	JC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418632	25938910	JC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4418632	25938910	JC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418632	25938910	Y. Soung	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418632	25938910	Y. Soung	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418632	25938910	Y. Soung	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418632	25938910	Y. Soung	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418632	25938910	Y. Surh	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1993828	17895989	AH	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1993828	17895989	AH	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1993828	17895989	GH	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1993828	17895989	GH	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1993828	17895989	GL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1993828	17895989	GL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1993828	17895989	GL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1993828	17895989	GL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1993828	17895989	GL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1993828	17895989	JM	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1993828	17895989	JM	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1993828	17895989	SS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1993828	17895989	SS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1993828	17895989	SS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1993828	17895989	SS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1993828	17895989	YT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1993828	17895989	YT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1993828	17895989	YT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1993828	17895989	YT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4644552	26609536	Divya Venkataraman	2	contributed equally to this work	contributed equally to this work	-	-	NO
4644552	26609536	Raghavendra Mundargi	2	contributed equally to this work	contributed equally to this work	-	-	NO
4876565	27217958	AG	2	performed the statistical analysis	performed the statistical analysis	Analyzed the data	Formal analysis	YES
4876565	27217958	BK	2	participated in the design of the study	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
4876565	27217958	CT	2	collected the samples and analyzed the data	collected the samples and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4876565	27217958	JKS	2	participated in the design of the study and interpreted the data	participated in the design of the study and interpreted the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
4876565	27217958	RN	2	performed experiments regarding contact activation	performed experiments regarding contact activation	Performed the experiments	Investigation	YES
4876565	27217958	SOH	2	conceived the study and wrote the manuscript	conceived the study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5897269	29651657	AK	2	supervised the manuscript	supervised the manuscript	-	Supervision	YES
5897269	29651657	All authors	2	contributed equally in writing this review article|read and approved the final manuscript	contributed equally in writing this review article	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5897269	29651657	All authors	2	contributed equally in writing this review article|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5897269	29651657	KN	2	contributed to the interpretation and assisted in the preparation of the manuscript	contributed to the interpretation and assisted in the preparation of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5897269	29651657	TH	2	contributed to the interpretation and assisted in the preparation of the manuscript	contributed to the interpretation and assisted in the preparation of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5897269	29651657	YN	2	wrote the manuscript and performed all the experiments	wrote the manuscript and performed all the experiments	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5826053	29515598	AM	2	discussed the manuscript	discussed the manuscript	-	-	NO
5826053	29515598	BK	2	did the real time pcr	did the real time pcr	Performed the experiments	Investigation	YES
5826053	29515598	DN	2	did some laboratory work related to real time pcr	did some laboratory work related to real time pcr	Performed the experiments	Investigation	YES
5826053	29515598	KA	2	did the design of the paper and the analysis	did the design of the paper and the analysis	Conceived and designed the experiments	-	YES
5826053	29515598	KH	2	did the design of the paper and the analysis	did the design of the paper and the analysis	Conceived and designed the experiments	-	YES
5826053	29515598	KM	2	did the design of the paper and the analysis	did the design of the paper and the analysis	Conceived and designed the experiments	-	YES
5826053	29515598	KS-A	2	discussed the manuscript	discussed the manuscript	-	-	NO
5826053	29515598	MP	2	improved the manuscript	improved the manuscript	Wrote the paper	Writing - Review & Editing	YES
5826053	29515598	MS	2	did the field testing	did the field testing	Performed the experiments	Investigation	YES
5826053	29515598	SM	2	did some laboratory work related to real time pcr	did some laboratory work related to real time pcr	Performed the experiments	Investigation	YES
6270811	25076142	I.E.I.	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6270811	25076142	I.K.I.	PLoS52	conceived and designed the experiments|conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6270811	25076142	I.K.I.	PLoS52	conceived and designed the experiments|conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6270811	25076142	V.C.C.	PLoS52	conceived and designed the experiments|who analyzed the spectral data and wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6270811	25076142	V.C.C.	PLoS52	conceived and designed the experiments|who analyzed the spectral data and wrote the manuscript	who analyzed the spectral data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5352815	28289256	All authors	2	contributed examples and text, and approved the final version of the manuscript	contributed examples and text, and approved the final version of the manuscript	Wrote the paper	Writing - Original Draft	YES
5352815	28289256	M.B.	2	contributed examples and text, and approved the final version of the manuscript	contributed examples and text, and approved the final version of the manuscript	Wrote the paper	Writing - Original Draft	YES
5352815	28289256	Transmission Research Retreat	2	where initial ideas for this manuscript were conceived	where initial ideas for this manuscript were conceived	Conceived and designed the experiments	Conceptualization	YES
1994583	17912372	AG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1994583	17912372	AG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1994583	17912372	AG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1994583	17912372	AG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1994583	17912372	AG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418654	25938663	AM	PLoS5	Conceived and designed the experiments|Wrote the paper|Data acquisition and management	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418654	25938663	AM	PLoS5	Conceived and designed the experiments|Wrote the paper|Data acquisition and management	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418654	25938663	AM	PLoS5	Conceived and designed the experiments|Wrote the paper|Data acquisition and management	Data acquisition and management	Performed the experiments	Investigation	YES
4418654	25938663	BL	PLoS5	Conceived and designed the experiments|Wrote the paper|Revision of manuscript for intellectual content	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418654	25938663	BL	PLoS5	Conceived and designed the experiments|Wrote the paper|Revision of manuscript for intellectual content	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418654	25938663	BL	PLoS5	Conceived and designed the experiments|Wrote the paper|Revision of manuscript for intellectual content	Revision of manuscript for intellectual content	Wrote the paper	Writing - Review & Editing	YES
4418654	25938663	FDB	PLoS5	Conceived and designed the experiments|Revision of manuscript for intellectual content	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418654	25938663	FDB	PLoS5	Conceived and designed the experiments|Revision of manuscript for intellectual content	Revision of manuscript for intellectual content	Wrote the paper	Writing - Review & Editing	YES
4418654	25938663	FM	PLoS5	Data acquisition and management|Revision of manuscript for intellectual content	Data acquisition and management	Performed the experiments	Investigation	YES
4418654	25938663	FM	PLoS5	Data acquisition and management|Revision of manuscript for intellectual content	Revision of manuscript for intellectual content	Wrote the paper	Writing - Review & Editing	YES
4418654	25938663	FV	PLoS5	Data acquisition and management|Revision of manuscript for intellectual content	Data acquisition and management	Performed the experiments	Investigation	YES
4418654	25938663	FV	PLoS5	Data acquisition and management|Revision of manuscript for intellectual content	Revision of manuscript for intellectual content	Wrote the paper	Writing - Review & Editing	YES
4418654	25938663	PL	PLoS5	Conceived and designed the experiments|Data acquisition and management|Revision of manuscript for intellectual content	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418654	25938663	PL	PLoS5	Conceived and designed the experiments|Data acquisition and management|Revision of manuscript for intellectual content	Data acquisition and management	Performed the experiments	Investigation	YES
4418654	25938663	PL	PLoS5	Conceived and designed the experiments|Data acquisition and management|Revision of manuscript for intellectual content	Revision of manuscript for intellectual content	Wrote the paper	Writing - Review & Editing	YES
4418654	25938663	RvK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418654	25938663	RvK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418654	25938663	RvK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418654	25938663	SS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Data acquisition and management	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418654	25938663	SS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Data acquisition and management	Analyzed the data	Analyzed the data	Formal analysis	YES
4418654	25938663	SS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Data acquisition and management	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418654	25938663	SS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Data acquisition and management	Data acquisition and management	Performed the experiments	Investigation	YES
4418654	25938663	TW	PLoS5	Data acquisition and management|Revision of manuscript for intellectual content	Data acquisition and management	Performed the experiments	Investigation	YES
4418654	25938663	TW	PLoS5	Data acquisition and management|Revision of manuscript for intellectual content	Revision of manuscript for intellectual content	Wrote the paper	Writing - Review & Editing	YES
3569642	23307470	All	2	authors reviewed the manuscript	authors reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
3569642	23307470	BA	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
3569642	23307470	CL	2	graded and screened human tumours	graded and screened human tumours	Performed the experiments	Investigation	YES
3569642	23307470	GAMC	2	supervised the project, designed experiments, and analysed the data|authors reviewed the manuscript	supervised the project, designed experiments, and analysed the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology|Supervision	YES
3569642	23307470	GAMC	2	supervised the project, designed experiments, and analysed the data|authors reviewed the manuscript	authors reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
3569642	23307470	HS	2	graded and screened human tumours	graded and screened human tumours	Performed the experiments	Investigation	YES
3569642	23307470	IU	2	graded and screened human tumours	graded and screened human tumours	Performed the experiments	Investigation	YES
3569642	23307470	JJL	2	provided material and were involved in manuscript preparations	provided material and were involved in manuscript preparations	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Original Draft	YES
3569642	23307470	KW	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
3569642	23307470	LAB	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
3569642	23307470	MJ	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
3569642	23307470	MSL	2	graded and screened human tumours	graded and screened human tumours	Performed the experiments	Investigation	YES
3569642	23307470	MY	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
3569642	23307470	NH	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
3569642	23307470	PW	2	designed and performed experiments and analysed the data	designed and performed experiments and analysed the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
3569642	23307470	RW	2	graded and screened human tumours	graded and screened human tumours	Performed the experiments	Investigation	YES
3569642	23307470	SAK	2	supervised the project, designed experiments, and analysed the data	supervised the project, designed experiments, and analysed the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology|Supervision	YES
3569642	23307470	SB	2	graded and screened human tumours	graded and screened human tumours	Performed the experiments	Investigation	YES
3569642	23307470	SGG	2	provided material and were involved in manuscript preparations	provided material and were involved in manuscript preparations	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Original Draft	YES
3569642	23307470	SR	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5784657	29370751	GZ	PLoS52	designed the experiments|wrote the paper	designed the experiments	Conceived and designed the experiments	Methodology	YES
5784657	29370751	GZ	PLoS52	designed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5784657	29370751	JZ	PLoS52	did the experiments	did the experiments	Performed the experiments	Investigation	YES
5784657	29370751	SC	PLoS52	analyzed data|wrote the paper	analyzed data	Analyzed the data	Formal analysis	YES
5784657	29370751	SC	PLoS52	analyzed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5784657	29370751	XC	PLoS52	did the experiments	did the experiments	Performed the experiments	Investigation	YES
5784657	29370751	XQ	PLoS52	did the experiments	did the experiments	Performed the experiments	Investigation	YES
5784657	29370751	ZH	PLoS52	designed the experiments|did the experiments|analyzed data|wrote the paper	designed the experiments	Conceived and designed the experiments	Methodology	YES
5784657	29370751	ZH	PLoS52	designed the experiments|did the experiments|analyzed data|wrote the paper	did the experiments	Performed the experiments	Investigation	YES
5784657	29370751	ZH	PLoS52	designed the experiments|did the experiments|analyzed data|wrote the paper	analyzed data	Analyzed the data	Formal analysis	YES
5784657	29370751	ZH	PLoS52	designed the experiments|did the experiments|analyzed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5826054	29515608	BS	7	designed the research|collected the data|wrote the manuscript, commented on and approved the final draft	designed the research	Conceived and designed the experiments	Methodology	YES
5826054	29515608	BS	7	designed the research|collected the data|wrote the manuscript, commented on and approved the final draft	collected the data	Performed the experiments	Investigation	YES
5826054	29515608	BS	7	designed the research|collected the data|wrote the manuscript, commented on and approved the final draft	wrote the manuscript, commented on and approved the final draft	Wrote the paper	Writing - Original Draft	YES
5826054	29515608	EC	7	designed the research|performed the statistical analysis and|wrote the manuscript, commented on and approved the final draft	designed the research	Conceived and designed the experiments	Methodology	YES
5826054	29515608	EC	7	designed the research|performed the statistical analysis and|wrote the manuscript, commented on and approved the final draft	performed the statistical analysis and	Analyzed the data	Formal analysis	YES
5826054	29515608	EC	7	designed the research|performed the statistical analysis and|wrote the manuscript, commented on and approved the final draft	wrote the manuscript, commented on and approved the final draft	Wrote the paper	Writing - Original Draft	YES
5826054	29515608	MM	7	designed the research|wrote the manuscript, commented on and approved the final draft	designed the research	Conceived and designed the experiments	Methodology	YES
5826054	29515608	MM	7	designed the research|wrote the manuscript, commented on and approved the final draft	wrote the manuscript, commented on and approved the final draft	Wrote the paper	Writing - Original Draft	YES
5826054	29515608	ST	7	designed the research|wrote the manuscript, commented on and approved the final draft	designed the research	Conceived and designed the experiments	Methodology	YES
5826054	29515608	ST	7	designed the research|wrote the manuscript, commented on and approved the final draft	wrote the manuscript, commented on and approved the final draft	Wrote the paper	Writing - Original Draft	YES
6270812	25153874	Feng Jing	PLoS52	performed research and analyzed the data	performed research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270812	25153874	Jinqian Yu	PLoS52	performed research and analyzed the data	performed research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270812	25153874	Xiao Wang	PLoS52	designed research	designed research	Conceived and designed the experiments	Methodology	YES
6270812	25153874	Xikai Shu	PLoS52	designed research|performed research and analyzed the data|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
6270812	25153874	Xikai Shu	PLoS52	designed research|performed research and analyzed the data|wrote the paper	performed research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270812	25153874	Xikai Shu	PLoS52	designed research|performed research and analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270812	25153874	Xueyong Wang	PLoS52	designed research|performed research and analyzed the data|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
6270812	25153874	Xueyong Wang	PLoS52	designed research|performed research and analyzed the data|wrote the paper	performed research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270812	25153874	Xueyong Wang	PLoS52	designed research|performed research and analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5899966	29658051	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5899966	29658051	CJ	PLoS52	made manuscript revisions	made manuscript revisions	Wrote the paper	Writing - Review & Editing	YES
5899966	29658051	DS	PLoS52	made manuscript revisions	made manuscript revisions	Wrote the paper	Writing - Review & Editing	YES
5899966	29658051	JS	PLoS52	conceived and supervised the study	conceived and supervised the study	Conceived and designed the experiments	Conceptualization|Supervision	YES
5899966	29658051	JZ	PLoS52	conceived and supervised the study|designed experiments and analyzed the data|performed the experiments	conceived and supervised the study	Conceived and designed the experiments	Conceptualization|Supervision	YES
5899966	29658051	JZ	PLoS52	conceived and supervised the study|designed experiments and analyzed the data|performed the experiments	designed experiments and analyzed the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5899966	29658051	JZ	PLoS52	conceived and supervised the study|designed experiments and analyzed the data|performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5899966	29658051	LY	PLoS52	designed experiments and analyzed the data|performed the experiments	designed experiments and analyzed the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5899966	29658051	LY	PLoS52	designed experiments and analyzed the data|performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5899966	29658051	Life Sciences	PLoS52	northwestern polytechnical university for providing all instruments used in the study	northwestern polytechnical university for providing all instruments used in the study	-	-	NO
5899966	29658051	The authors	PLoS52	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5899966	29658051	XX	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5899966	29658051	YZ	PLoS52	provided help in the experimental design and data analysis	provided help in the experimental design and data analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Methodology|Resources	YES
4418656	25938837	AH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418656	25938837	AH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418656	25938837	AH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418656	25938837	AH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418656	25938837	AH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418656	25938837	DFA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418656	25938837	DFA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418656	25938837	DFA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418656	25938837	DFA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418656	25938837	HK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418656	25938837	HK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4418656	25938837	HK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418656	25938837	MHK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418656	25938837	MHK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418656	25938837	MHK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418656	25938837	MHK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418656	25938837	RWJC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418656	25938837	RWJC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418656	25938837	RWJC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418656	25938837	RWJC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418656	25938837	RWJC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418656	25938837	SDG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418656	25938837	SDG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5352816	28289257	A.H.	2	contributed model derivation and analysis	contributed model derivation and analysis	Performed the experiments	Methodology	YES
5352816	28289257	A.R.E.	2	acquired the data	acquired the data	Performed the experiments	Investigation	YES
5352816	28289257	All authors	2	contributed to the conception and design of the article	contributed to the conception and design of the article	Conceived and designed the experiments	Conceptualization	YES
5352816	28289257	C.E.C.	2	contributed model derivation and analysis|wrote the first version of the article and all authors contributed to revisions and final editing	contributed model derivation and analysis	Performed the experiments	Methodology	YES
5352816	28289257	C.E.C.	2	contributed model derivation and analysis|wrote the first version of the article and all authors contributed to revisions and final editing	wrote the first version of the article and all authors contributed to revisions and final editing	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5352816	28289257	J.C.	2	acquired the data	acquired the data	Performed the experiments	Investigation	YES
5352816	28289257	J.G.W.	2	acquired the data|calculated the phylogenetic metrics and cleaned and analysed the data|wrote the first version of the article and all authors contributed to revisions and final editing	acquired the data	Performed the experiments	Investigation	YES
5352816	28289257	J.G.W.	2	acquired the data|calculated the phylogenetic metrics and cleaned and analysed the data|wrote the first version of the article and all authors contributed to revisions and final editing	calculated the phylogenetic metrics and cleaned and analysed the data	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5352816	28289257	J.G.W.	2	acquired the data|calculated the phylogenetic metrics and cleaned and analysed the data|wrote the first version of the article and all authors contributed to revisions and final editing	wrote the first version of the article and all authors contributed to revisions and final editing	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5352816	28289257	S.J.P.	2	calculated the phylogenetic metrics and cleaned and analysed the data	calculated the phylogenetic metrics and cleaned and analysed the data	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
1994584	17912340	BS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1994584	17912340	BS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1994584	17912340	LC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1994584	17912340	LC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1994584	17912340	LC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1994584	17912340	NN	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1994584	17912340	NN	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1994584	17912340	PJ	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1994584	17912340	PJ	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1994584	17912340	RK	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1994584	17912340	SS	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1994584	17912340	SS	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1994584	17912340	TD	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1994584	17912340	TD	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1994584	17912340	TD	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3569643	23239471	AI	2	designed the study|designed the experiments in fish|performed the experiments in fish|analysed the data and wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
3569643	23239471	AI	2	designed the study|designed the experiments in fish|performed the experiments in fish|analysed the data and wrote the manuscript	designed the experiments in fish	Conceived and designed the experiments	Methodology	YES
3569643	23239471	AI	2	designed the study|designed the experiments in fish|performed the experiments in fish|analysed the data and wrote the manuscript	performed the experiments in fish	Performed the experiments	Investigation	YES
3569643	23239471	AI	2	designed the study|designed the experiments in fish|performed the experiments in fish|analysed the data and wrote the manuscript	analysed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3569643	23239471	AR	2	performed the experiments in fish	performed the experiments in fish	Performed the experiments	Investigation	YES
3569643	23239471	BF	2	designed the study|designed the experiments in fish|analysed the data and wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
3569643	23239471	BF	2	designed the study|designed the experiments in fish|analysed the data and wrote the manuscript	designed the experiments in fish	Conceived and designed the experiments	Methodology	YES
3569643	23239471	BF	2	designed the study|designed the experiments in fish|analysed the data and wrote the manuscript	analysed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3569643	23239471	DG	2	measured mrc complexes activities in fish	measured mrc complexes activities in fish	Performed the experiments	Investigation	YES
3569643	23239471	GC	2	performed the experiments in fish	performed the experiments in fish	Performed the experiments	Investigation	YES
3569643	23239471	IC	2	designed the experiments in fish|performed the experiments in fish|analysed the data and wrote the manuscript	designed the experiments in fish	Conceived and designed the experiments	Methodology	YES
3569643	23239471	IC	2	designed the experiments in fish|performed the experiments in fish|analysed the data and wrote the manuscript	performed the experiments in fish	Performed the experiments	Investigation	YES
3569643	23239471	IC	2	designed the experiments in fish|performed the experiments in fish|analysed the data and wrote the manuscript	analysed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3569643	23239471	IF	2	designed and performed the experiments in yeast	designed and performed the experiments in yeast	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3569643	23239471	JQ	2	designed and performed the experiments in yeast	designed and performed the experiments in yeast	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3569643	23239471	MZ	2	contributed conceptual advice	contributed conceptual advice	Conceived and designed the experiments	Conceptualization	YES
3569643	23239471	PB	2	designed the experiments in fish|analysed the data and wrote the manuscript	designed the experiments in fish	Conceived and designed the experiments	Methodology	YES
3569643	23239471	PB	2	designed the experiments in fish|analysed the data and wrote the manuscript	analysed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3569643	23239471	PG	2	designed and performed the experiments in yeast	designed and performed the experiments in yeast	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3569643	23239471	RT	2	performed transmission electron microscopy	performed transmission electron microscopy	Performed the experiments	Investigation	YES
5785805	29370753	All authors	PLoS52	discussed the results and commented on the manuscript	discussed the results and commented on the manuscript	-	-	NO
5785805	29370753	GP	PLoS52	conceived and designed the experiments|conceived the project	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5785805	29370753	GP	PLoS52	conceived and designed the experiments|conceived the project	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5785805	29370753	HL	PLoS52	conceived and designed the experiments|conceived the project	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5785805	29370753	HL	PLoS52	conceived and designed the experiments|conceived the project	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5785805	29370753	LL	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5785805	29370753	SG	PLoS52	provided pedigree information and genotyping	provided pedigree information and genotyping	Performed the experiments	Investigation	YES
5785805	29370753	WW	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5785805	29370753	XZ	PLoS52	performed the experiments|supervised manuscript discussion and writing	performed the experiments	Performed the experiments	Investigation	YES
5785805	29370753	XZ	PLoS52	performed the experiments|supervised manuscript discussion and writing	supervised manuscript discussion and writing	Wrote the paper	Supervision|Writing - Original Draft	YES
5785805	29370753	YC	PLoS52	performed the experiments|supervised manuscript discussion and writing	performed the experiments	Performed the experiments	Investigation	YES
5785805	29370753	YC	PLoS52	performed the experiments|supervised manuscript discussion and writing	supervised manuscript discussion and writing	Wrote the paper	Supervision|Writing - Original Draft	YES
5785805	29370753	YJ	PLoS52	supervised manuscript discussion and writing	supervised manuscript discussion and writing	Wrote the paper	Supervision|Writing - Original Draft	YES
5785805	29370753	YL	PLoS52	performed the experiments|performed the experiments|performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5785805	29370753	YL	PLoS52	performed the experiments|performed the experiments|performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5785805	29370753	YL	PLoS52	performed the experiments|performed the experiments|performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5785805	29370753	YS	PLoS52	conceived the project	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5785805	29370753	ZZ	PLoS52	conceived the project	conceived the project	Conceived and designed the experiments	Conceptualization	YES
6270813	25365294	Ben Liu	PLoS52	performed research and analyzed the data|wrote the paper	performed research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270813	25365294	Ben Liu	PLoS52	performed research and analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270813	25365294	Huan Zhang	PLoS52	performed research and analyzed the data	performed research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270813	25365294	Liu-Ye Yan	PLoS52	performed research and analyzed the data	performed research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270813	25365294	Qiang Wang	PLoS52	designed research|performed research and analyzed the data|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
6270813	25365294	Qiang Wang	PLoS52	designed research|performed research and analyzed the data|wrote the paper	performed research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270813	25365294	Qiang Wang	PLoS52	designed research|performed research and analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270813	25365294	Xian-Xian Li	PLoS52	performed research and analyzed the data	performed research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270813	25365294	Xiao Ruan	PLoS52	performed research and analyzed the data|wrote the paper	performed research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270813	25365294	Xiao Ruan	PLoS52	performed research and analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5826057	29515610	D-L	PLoS52	discussed and interpreted the data|also participated in the critical reading, writing, and correction of the manuscript	discussed and interpreted the data	Analyzed the data	Formal analysis	YES
5826057	29515610	D-L	PLoS52	discussed and interpreted the data|also participated in the critical reading, writing, and correction of the manuscript	also participated in the critical reading, writing, and correction of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5826057	29515610	DR	PLoS52	conceived and designed the experiments|also participated in the critical reading, writing, and correction of the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5826057	29515610	DR	PLoS52	conceived and designed the experiments|also participated in the critical reading, writing, and correction of the manuscript	also participated in the critical reading, writing, and correction of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5826057	29515610	MB	PLoS52	conceived and designed the experiments|performed the experiments|drafted and wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5826057	29515610	MB	PLoS52	conceived and designed the experiments|performed the experiments|drafted and wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5826057	29515610	MB	PLoS52	conceived and designed the experiments|performed the experiments|drafted and wrote the manuscript	drafted and wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5826057	29515610	NR	PLoS52	conceived and designed the experiments|drafted and wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5826057	29515610	NR	PLoS52	conceived and designed the experiments|drafted and wrote the manuscript	drafted and wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6430085	30996962	HJ	PLoS52	conceived and designed the study|wrote the paper	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6430085	30996962	HJ	PLoS52	conceived and designed the study|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6430085	30996962	MZ	PLoS52	conceived and designed the study|conducted most of the simulations and analyzed the results|wrote the paper	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6430085	30996962	MZ	PLoS52	conceived and designed the study|conducted most of the simulations and analyzed the results|wrote the paper	conducted most of the simulations and analyzed the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6430085	30996962	MZ	PLoS52	conceived and designed the study|conducted most of the simulations and analyzed the results|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6430085	30996962	RN	PLoS52	conceived and designed the study|wrote the paper	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6430085	30996962	RN	PLoS52	conceived and designed the study|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5352817	28289258	A.M.	2	designed and developed the models|designed and developed the models	designed and developed the models	Conceived and designed the experiments|Performed the experiments	Methodology	YES
5352817	28289258	A.M.	2	designed and developed the models|designed and developed the models	designed and developed the models	Conceived and designed the experiments|Performed the experiments	Methodology	YES
5352817	28289258	All authors	2	contributed to analysis of model output and biological interpretations, and have read and approved the final manuscript	contributed to analysis of model output and biological interpretations, and have read and approved the final manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
5352817	28289258	J.S.	2	designed and developed the models	designed and developed the models	Conceived and designed the experiments|Performed the experiments	Methodology	YES
4418659	25938774	CQH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418659	25938774	CQH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418659	25938774	CQH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418659	25938774	FZ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418659	25938774	FZ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418659	25938774	FZ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418659	25938774	FZ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418659	25938774	JPZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418659	25938774	JPZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4418659	25938774	JPZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418659	25938774	WQ	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4418659	25938774	WQ	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5904092	29667106	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5904092	29667106	DG	2	conducted the experiments and analyzed the results	conducted the experiments and analyzed the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5904092	29667106	FC	2	interpreted data	interpreted data	Analyzed the data	Formal analysis	YES
5904092	29667106	JL	2	conceived the experiments	conceived the experiments	Conceived and designed the experiments	Conceptualization	YES
5904092	29667106	MM	2	conducted the experiments and analyzed the results|interpreted data|wrote the manuscript	conducted the experiments and analyzed the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5904092	29667106	MM	2	conducted the experiments and analyzed the results|interpreted data|wrote the manuscript	interpreted data	Analyzed the data	Formal analysis	YES
5904092	29667106	MM	2	conducted the experiments and analyzed the results|interpreted data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5904092	29667106	MO	2	interpreted data|edited the manuscript	interpreted data	Analyzed the data	Formal analysis	YES
5904092	29667106	MO	2	interpreted data|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5904092	29667106	QW	2	conducted the experiments and analyzed the results	conducted the experiments and analyzed the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5904092	29667106	XJ	2	conceived the experiments	conceived the experiments	Conceived and designed the experiments	Conceptualization	YES
6270814	25153871	Kun Zhang	2	jointly suggested the research work and led the project	jointly suggested the research work and led the project	Performed the experiments	Investigation	YES
6270814	25153871	Panpan Wu	2	perform the experiment and analyzed the data|led the writing, edited and revised the manuscript	perform the experiment and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270814	25153871	Panpan Wu	2	perform the experiment and analyzed the data|led the writing, edited and revised the manuscript	led the writing, edited and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6270814	25153871	Ping He	2	perform the experiment and analyzed the data	perform the experiment and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270814	25153871	Suqing Zhao	2	jointly suggested the research work and led the project	jointly suggested the research work and led the project	Performed the experiments	Investigation	YES
6270814	25153871	Tianming Huang	2	led the writing, edited and revised the manuscript	led the writing, edited and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6270814	25153871	Yujing Lu	2	led the writing, edited and revised the manuscript	led the writing, edited and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3569644	23307490	AJ	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
3569644	23307490	BL	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
3569644	23307490	CA	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
3569644	23307490	CS	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
3569644	23307490	DS	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
3569644	23307490	GMD-T	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
3569644	23307490	KF	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
3569644	23307490	KM-D	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
3569644	23307490	MB-D	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
3569644	23307490	MK	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
3569644	23307490	MR	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
3569644	23307490	MS	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
3569644	23307490	NG	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
3569644	23307490	OS	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
3569644	23307490	PK	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
3569644	23307490	SH	2	designed and directed research|wrote the manuscript	designed and directed research	Conceived and designed the experiments	Methodology|Supervision	YES
3569644	23307490	SH	2	designed and directed research|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3569644	23307490	TS	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
3569644	23307490	WS	2	designed and directed research	designed and directed research	Conceived and designed the experiments	Methodology|Supervision	YES
5785814	29370772	AAG	2	helped with the and wrote the manuscript with the valuable|helped with the data interpretation, analyses, and manuscript review	helped with the and wrote the manuscript with the valuable	Wrote the paper	Writing - Original Draft	YES
5785814	29370772	AAG	2	helped with the and wrote the manuscript with the valuable|helped with the data interpretation, analyses, and manuscript review	helped with the data interpretation, analyses, and manuscript review	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5785814	29370772	ASMC	2	performed the qtl permutation analysis	performed the qtl permutation analysis	Performed the experiments	Investigation	YES
5785814	29370772	CB	2	designed the study, analyzed and interpreted the data, and wrote the manuscript with the valuable	designed the study, analyzed and interpreted the data, and wrote the manuscript with the valuable	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5785814	29370772	GCMM	2	performed the snp validation|performed the genotyping	performed the snp validation	Performed the experiments	Investigation|Validation	YES
5785814	29370772	GCMM	2	performed the snp validation|performed the genotyping	performed the genotyping	Performed the experiments	Investigation	YES
5785814	29370772	GG	2	performed the sequencing	performed the sequencing	Performed the experiments	Investigation	YES
5785814	29370772	LLC	2	designed the study, reviewed the manuscript and provided overall supervision	designed the study, reviewed the manuscript and provided overall supervision	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Review & Editing	YES
5785814	29370772	MCL	2	provided the biological material, helped in the interpretation of results and reviewed the manuscript	provided the biological material, helped in the interpretation of results and reviewed the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
5785814	29370772	MP	2	performed the sequencing	performed the sequencing	Performed the experiments	Investigation	YES
5785814	29370772	PDSCM	2	performed the sequencing	performed the sequencing	Performed the experiments	Investigation	YES
5785814	29370772	TFG	2	performed the genotyping	performed the genotyping	Performed the experiments	Investigation	YES
5826081	29515607	AJ	2	performed the modeling	performed the modeling	Performed the experiments	Investigation|Methodology	YES
5826081	29515607	AK	2	provided lake data	provided lake data	Contributed reagents/materials/analysis tools	Resources	YES
5826081	29515607	AW	2	provided lake data	provided lake data	Contributed reagents/materials/analysis tools	Resources	YES
5826081	29515607	All authors	2	contributed to discussions and the writing of different parts of the text	contributed to discussions and the writing of different parts of the text	Wrote the paper	Writing - Original Draft	YES
5826081	29515607	CS	2	provided lake data	provided lake data	Contributed reagents/materials/analysis tools	Resources	YES
5826081	29515607	EB	2	provided lake data|confirms the absence of any other collaboration	provided lake data	Contributed reagents/materials/analysis tools	Resources	YES
5826081	29515607	EB	2	provided lake data|confirms the absence of any other collaboration	confirms the absence of any other collaboration	-	-	NO
5826081	29515607	EJ	2	provided lake data	provided lake data	Contributed reagents/materials/analysis tools	Resources	YES
5826081	29515607	EvD	2	provided lake data	provided lake data	Contributed reagents/materials/analysis tools	Resources	YES
5826081	29515607	GP	2	provided lake data	provided lake data	Contributed reagents/materials/analysis tools	Resources	YES
5826081	29515607	H-HS	2	provided lake data	provided lake data	Contributed reagents/materials/analysis tools	Resources	YES
5826081	29515607	IB	2	provided lake data	provided lake data	Contributed reagents/materials/analysis tools	Resources	YES
5826081	29515607	JJ	2	performed the modeling	performed the modeling	Performed the experiments	Investigation|Methodology	YES
5826081	29515607	JK	2	provided lake data	provided lake data	Contributed reagents/materials/analysis tools	Resources	YES
5826081	29515607	JR	2	provided lake data	provided lake data	Contributed reagents/materials/analysis tools	Resources	YES
5826081	29515607	KvdW	2	provided lake data	provided lake data	Contributed reagents/materials/analysis tools	Resources	YES
5826081	29515607	L-AH	2	provided lake data	provided lake data	Contributed reagents/materials/analysis tools	Resources	YES
5826081	29515607	MA	2	provided lake data	provided lake data	Contributed reagents/materials/analysis tools	Resources	YES
5826081	29515607	MG	2	performed the modeling	performed the modeling	Performed the experiments	Investigation|Methodology	YES
5826081	29515607	MS	2	provided lake data	provided lake data	Contributed reagents/materials/analysis tools	Resources	YES
5826081	29515607	NW	2	provided lake data	provided lake data	Contributed reagents/materials/analysis tools	Resources	YES
5826081	29515607	RN	2	provided lake data	provided lake data	Contributed reagents/materials/analysis tools	Resources	YES
5826081	29515607	SH	2	conceived the presented idea, wrote the manuscript and performed the literature research	conceived the presented idea, wrote the manuscript and performed the literature research	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
5826081	29515607	ST	2	performed the modeling	performed the modeling	Performed the experiments	Investigation|Methodology	YES
5826081	29515607	TD	2	provided lake data	provided lake data	Contributed reagents/materials/analysis tools	Resources	YES
5826081	29515607	TK	2	provided lake data	provided lake data	Contributed reagents/materials/analysis tools	Resources	YES
5826081	29515607	TL	2	provided lake data	provided lake data	Contributed reagents/materials/analysis tools	Resources	YES
5826081	29515607	The authors	2	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	Performed the experiments	Investigation	YES
5826081	29515607	WM	2	performed the modeling	performed the modeling	Performed the experiments	Investigation|Methodology	YES
4418660	25938422	IRW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418660	25938422	IRW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418660	25938422	IRW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418660	25938422	LMJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418660	25938422	LMJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418660	25938422	LMJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418660	25938422	LMJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418660	25938422	WJF	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418660	25938422	WJF	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270815	25006789	Di Wu	2	performed the main experimental work	performed the main experimental work	Performed the experiments	Investigation	YES
6270815	25006789	Haobo Han	2	performed the main experimental work	performed the main experimental work	Performed the experiments	Investigation	YES
6270815	25006789	Hui Shi	2	performed the main experimental work	performed the main experimental work	Performed the experiments	Investigation	YES
6270815	25006789	Jianxu Zhang	2	conducted the nmr and gpc measurement, and also revised the manuscript	conducted the nmr and gpc measurement, and also revised the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
6270815	25006789	Min Wang	2	performed the main experimental work	performed the main experimental work	Performed the experiments	Investigation	YES
6270815	25006789	Quanshun Li	2	designed the experiment, analyzed the data and wrote the paper	designed the experiment, analyzed the data and wrote the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
6270815	25006789	Shuang Wang	2	designed the experiment, analyzed the data and wrote the paper	designed the experiment, analyzed the data and wrote the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
6270815	25006789	Zhen Xing	2	analyzed the data and prepared the figures and tables	analyzed the data and prepared the figures and tables	Analyzed the data	Formal analysis|Visualization	YES
5904096	29667033	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5904096	29667033	FS	2	performed the research, analyzed data, and wrote this manuscript	performed the research, analyzed data, and wrote this manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5904096	29667033	JY	2	performed the research, analyzed data, and wrote this manuscript	performed the research, analyzed data, and wrote this manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5904096	29667033	KO	2	designed the research and polished the manuscript	designed the research and polished the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5904096	29667033	LH	2	performed the research, analyzed data, and wrote this manuscript	performed the research, analyzed data, and wrote this manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5904096	29667033	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5904096	29667033	XFY	2	performed the research, analyzed data, and wrote this manuscript	performed the research, analyzed data, and wrote this manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5904096	29667033	XPY	2	designed the research and polished the manuscript	designed the research and polished the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5904096	29667033	XS	2	performed the research, analyzed data, and wrote this manuscript	performed the research, analyzed data, and wrote this manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
1994586	17912376	EP	PLoS5	Analyzed the data|Wrote the paper|Conceived the analysis	Analyzed the data	Analyzed the data	Formal analysis	YES
1994586	17912376	EP	PLoS5	Analyzed the data|Wrote the paper|Conceived the analysis	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1994586	17912376	EP	PLoS5	Analyzed the data|Wrote the paper|Conceived the analysis	Conceived the analysis	Conceived and designed the experiments	Conceptualization	YES
3569645	23300147	All the authors	2	contributed to the preparation of the manuscript	contributed to the preparation of the manuscript	Wrote the paper	Writing - Original Draft	YES
3569645	23300147	CMS	2	performed most of the experiments|designed the experiments	performed most of the experiments	Performed the experiments	Investigation	YES
3569645	23300147	CMS	2	performed most of the experiments|designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
3569645	23300147	DG	2	carried out the microarrays experiments	carried out the microarrays experiments	Performed the experiments	Investigation	YES
3569645	23300147	MST	2	in anoikis and cellular motility assays	in anoikis and cellular motility assays	Performed the experiments	Investigation	YES
3569645	23300147	PdlG	2	processed the microarrays and human data, respectively	processed the microarrays and human data, respectively	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
3569645	23300147	SH	2	designed the experiments|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
3569645	23300147	SH	2	designed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3569645	23300147	STdM	2	processed the microarrays and human data, respectively	processed the microarrays and human data, respectively	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5352818	28289259	All authors	2	contributed substantively to the paper	contributed substantively to the paper	-	-	NO
5352818	28289259	J.P.W.	2	contributed substantively to the paper	contributed substantively to the paper	-	-	NO
4418662	25938823	AALT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418662	25938823	AALT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418662	25938823	AALT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418662	25938823	AALT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418662	25938823	AALT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418662	25938823	BRDCLJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418662	25938823	BRDCLJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418662	25938823	BRDCLJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418662	25938823	BRDCLJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418662	25938823	BRDCLJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418662	25938823	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418662	25938823	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418662	25938823	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418662	25938823	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418662	25938823	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5785835	29370748	AC	2	participated in analysis	participated in analysis	-	-	NO
5785835	29370748	AH	2	provided data	provided data	Contributed reagents/materials/analysis tools	Resources	YES
5785835	29370748	DZ	2	participated in analysis	participated in analysis	-	-	NO
5785835	29370748	HM	2	participated in analysis|critically reviewed the manuscript and contributed intellectual content to the manuscript	participated in analysis	-	-	NO
5785835	29370748	HM	2	participated in analysis|critically reviewed the manuscript and contributed intellectual content to the manuscript	critically reviewed the manuscript and contributed intellectual content to the manuscript	Wrote the paper	Writing - Review & Editing	YES
5785835	29370748	LF	2	critically reviewed the manuscript and contributed intellectual content to the manuscript	critically reviewed the manuscript and contributed intellectual content to the manuscript	Wrote the paper	Writing - Review & Editing	YES
5785835	29370748	LMT	2	provided data|critically reviewed the manuscript and contributed intellectual content to the manuscript	provided data	Contributed reagents/materials/analysis tools	Resources	YES
5785835	29370748	LMT	2	provided data|critically reviewed the manuscript and contributed intellectual content to the manuscript	critically reviewed the manuscript and contributed intellectual content to the manuscript	Wrote the paper	Writing - Review & Editing	YES
5785835	29370748	MV	2	participated in analysis	participated in analysis	-	-	NO
5785835	29370748	MvI	2	participated in analysis|critically reviewed the manuscript and contributed intellectual content to the manuscript	participated in analysis	-	-	NO
5785835	29370748	MvI	2	participated in analysis|critically reviewed the manuscript and contributed intellectual content to the manuscript	critically reviewed the manuscript and contributed intellectual content to the manuscript	Wrote the paper	Writing - Review & Editing	YES
5785835	29370748	PACH	2	supervised and planned the study|critically reviewed the manuscript and contributed intellectual content to the manuscript	supervised and planned the study	Conceived and designed the experiments	Conceptualization|Supervision	YES
5785835	29370748	PACH	2	supervised and planned the study|critically reviewed the manuscript and contributed intellectual content to the manuscript	critically reviewed the manuscript and contributed intellectual content to the manuscript	Wrote the paper	Writing - Review & Editing	YES
5785835	29370748	PK	2	critically reviewed the manuscript and contributed intellectual content to the manuscript	critically reviewed the manuscript and contributed intellectual content to the manuscript	Wrote the paper	Writing - Review & Editing	YES
5785835	29370748	PvtH	2	participated in analysis	participated in analysis	-	-	NO
5785835	29370748	RCS	2	critically reviewed the manuscript and contributed intellectual content to the manuscript	critically reviewed the manuscript and contributed intellectual content to the manuscript	Wrote the paper	Writing - Review & Editing	YES
5785835	29370748	SY	2	analyzed the data and wrote the paper	analyzed the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5785835	29370748	TAD	2	participated in analysis|critically reviewed the manuscript and contributed intellectual content to the manuscript	participated in analysis	-	-	NO
5785835	29370748	TAD	2	participated in analysis|critically reviewed the manuscript and contributed intellectual content to the manuscript	critically reviewed the manuscript and contributed intellectual content to the manuscript	Wrote the paper	Writing - Review & Editing	YES
5785835	29370748	TK	2	participated in analysis|critically reviewed the manuscript and contributed intellectual content to the manuscript	participated in analysis	-	-	NO
5785835	29370748	TK	2	participated in analysis|critically reviewed the manuscript and contributed intellectual content to the manuscript	critically reviewed the manuscript and contributed intellectual content to the manuscript	Wrote the paper	Writing - Review & Editing	YES
1994587	17925853	AD	PLoS5	Drafted portions of paper|Conducted legal research|Provided critical feedback	Drafted portions of paper	Wrote the paper	Writing - Original Draft	YES
1994587	17925853	AD	PLoS5	Drafted portions of paper|Conducted legal research|Provided critical feedback	Conducted legal research	Performed the experiments	Investigation	YES
1994587	17925853	AD	PLoS5	Drafted portions of paper|Conducted legal research|Provided critical feedback	Provided critical feedback	-	-	NO
1994587	17925853	LW	PLoS5	Wrote the paper|Conceived and designed the project|Oversaw the legal research|Conducted additional legal research|Analyzed the statutes	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1994587	17925853	LW	PLoS5	Wrote the paper|Conceived and designed the project|Oversaw the legal research|Conducted additional legal research|Analyzed the statutes	Conceived and designed the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
1994587	17925853	LW	PLoS5	Wrote the paper|Conceived and designed the project|Oversaw the legal research|Conducted additional legal research|Analyzed the statutes	Oversaw the legal research	-	Supervision	YES
1994587	17925853	LW	PLoS5	Wrote the paper|Conceived and designed the project|Oversaw the legal research|Conducted additional legal research|Analyzed the statutes	Conducted additional legal research	Performed the experiments	Investigation	YES
1994587	17925853	LW	PLoS5	Wrote the paper|Conceived and designed the project|Oversaw the legal research|Conducted additional legal research|Analyzed the statutes	Analyzed the statutes	Analyzed the data	Formal analysis	YES
1994587	17925853	TL	PLoS5	Analyzed the data|Drafted portions of paper|Conducted literature reviews|Provided critical feedback on drafts	Analyzed the data	Analyzed the data	Formal analysis	YES
1994587	17925853	TL	PLoS5	Analyzed the data|Drafted portions of paper|Conducted literature reviews|Provided critical feedback on drafts	Drafted portions of paper	Wrote the paper	Writing - Original Draft	YES
1994587	17925853	TL	PLoS5	Analyzed the data|Drafted portions of paper|Conducted literature reviews|Provided critical feedback on drafts	Conducted literature reviews	Performed the experiments	Formal analysis|Investigation	YES
1994587	17925853	TL	PLoS5	Analyzed the data|Drafted portions of paper|Conducted literature reviews|Provided critical feedback on drafts	Provided critical feedback on drafts	Wrote the paper	Writing - Original Draft	YES
6270816	24642911	All authors	2	contributed to the preparation of the manuscript	contributed to the preparation of the manuscript	Wrote the paper	Writing - Original Draft	YES
6270816	24642911	Martha Induli	2	extracted the roots, fractionated the extract and isolated the constituents	extracted the roots, fractionated the extract and isolated the constituents	Performed the experiments	Investigation	YES
6270816	24642911	Negera Abdissa	2	extracted the roots, fractionated the extract and isolated the constituents	extracted the roots, fractionated the extract and isolated the constituents	Performed the experiments	Investigation	YES
4418663	25939015	HL	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418663	25939015	JQ	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418663	25939015	LD	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418663	25939015	RL	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418663	25939015	XK	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418663	25939015	XQ	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418663	25939015	XQ	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418663	25939015	XS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5352820	28289261	A.B.	2	conceived the project	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5352820	28289261	All authors	2	contributed to and revised the manuscript	contributed to and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5352820	28289261	C.K.C.	2	analysed the data, made the figures and wrote the statistical methods section	analysed the data, made the figures and wrote the statistical methods section	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Visualization|Writing - Original Draft	YES
5352820	28289261	H.C.L.	2	conceived the project|collected the data and wrote the first draft of the manuscript	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5352820	28289261	H.C.L.	2	conceived the project|collected the data and wrote the first draft of the manuscript	collected the data and wrote the first draft of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5352820	28289261	S.A.W.	2	conceived the project	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5906409	29671101	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5906409	29671101	GY	PLoS52	carried out the experiments|designed the research	carried out the experiments	Performed the experiments	Investigation	YES
5906409	29671101	GY	PLoS52	carried out the experiments|designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
5906409	29671101	JG	PLoS52	carried out the experiments|wrote the paper	carried out the experiments	Performed the experiments	Investigation	YES
5906409	29671101	JG	PLoS52	carried out the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5906409	29671101	SZ	PLoS52	carried out the experiments|wrote the paper	carried out the experiments	Performed the experiments	Investigation	YES
5906409	29671101	SZ	PLoS52	carried out the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5906409	29671101	XZ	PLoS52	carried out the experiments|designed the research	carried out the experiments	Performed the experiments	Investigation	YES
5906409	29671101	XZ	PLoS52	carried out the experiments|designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
5906409	29671101	ZC	PLoS52	designed the research|obtained the funding	designed the research	Conceived and designed the experiments	Methodology	YES
5906409	29671101	ZC	PLoS52	designed the research|obtained the funding	obtained the funding	-	Funding acquisition	YES
5826184	29515617	CD	2	reviewed the materials and offered insights on the dynamics of environmental interactions	reviewed the materials and offered insights on the dynamics of environmental interactions	-	-	NO
5826184	29515617	JH	2	wrote the paper and conducted the analysis	wrote the paper and conducted the analysis	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
1994588	17912375	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1994588	17912375	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1994588	17912375	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1994588	17912375	AS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1994588	17912375	EU	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1994588	17912375	FG	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1994588	17912375	GF	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1994588	17912375	KW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1994588	17912375	KW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1994588	17912375	KW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1994588	17912375	SM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1994588	17912375	WV	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4644820	26609520	Adam Kretowski	2	conceived the idea for the study, contributed to the design of the research, interpreted the results, and wrote the paper|coordinated funding for the project	conceived the idea for the study, contributed to the design of the research, interpreted the results, and wrote the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
4644820	26609520	Adam Kretowski	2	conceived the idea for the study, contributed to the design of the research, interpreted the results, and wrote the paper|coordinated funding for the project	coordinated funding for the project	-	Funding acquisition|Project administration	YES
4644820	26609520	Edyta Adamska	2	conceived the idea for the study, contributed to the design of the research, interpreted the results, and wrote the paper|were involved in the data collection	conceived the idea for the study, contributed to the design of the research, interpreted the results, and wrote the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
4644820	26609520	Edyta Adamska	2	conceived the idea for the study, contributed to the design of the research, interpreted the results, and wrote the paper|were involved in the data collection	were involved in the data collection	Performed the experiments	Investigation	YES
4644820	26609520	Joanna Goscik	2	performed statistical analyses and contributed to the discussion	performed statistical analyses and contributed to the discussion	Analyzed the data	Formal analysis	YES
4644820	26609520	Lucyna Ostrowska	2	conceived the idea for the study, contributed to the design of the research, interpreted the results, and wrote the paper	conceived the idea for the study, contributed to the design of the research, interpreted the results, and wrote the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
4644820	26609520	Magdalena Waszczeniuk	2	were involved in the data collection	were involved in the data collection	Performed the experiments	Investigation	YES
4644820	26609520	Maria Gorska	2	conceived the idea for the study, contributed to the design of the research, interpreted the results, and wrote the paper|coordinated funding for the project	conceived the idea for the study, contributed to the design of the research, interpreted the results, and wrote the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
4644820	26609520	Maria Gorska	2	conceived the idea for the study, contributed to the design of the research, interpreted the results, and wrote the paper|coordinated funding for the project	coordinated funding for the project	-	Funding acquisition|Project administration	YES
5787230	29374456	BCFtools	2	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5787230	29374456	CB	2	participated in the design of the study and in the revision of the manuscript	participated in the design of the study and in the revision of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5787230	29374456	FSS	2	participated in the design of the study and the revision of the manuscript	participated in the design of the study and the revision of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5787230	29374456	MF	2	carried out the experiment, interpreted results and prepared the manuscript	carried out the experiment, interpreted results and prepared the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5787230	29374456	MS	2	supervised the experiment, participated in the design of the study, developed the program for statistical analyses and revised the manuscript	supervised the experiment, participated in the design of the study, developed the program for statistical analyses and revised the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Software|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
5787230	29374456	PLINK	2	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5787230	29374456	SAM	2	supervised the experiment and participated in the revision of the manuscript	supervised the experiment and participated in the revision of the manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
4418664	25938802	CC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418664	25938802	CW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418664	25938802	HS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418664	25938802	ITT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418664	25938802	ITT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418664	25938802	ITT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418664	25938802	ITT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418664	25938802	JX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418664	25938802	JX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418664	25938802	JX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418664	25938802	JX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418664	25938802	LZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418664	25938802	SC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418664	25938802	SD	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418664	25938802	WT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418664	25938802	WT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418664	25938802	WT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418664	25938802	WT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1994589	17925851	LN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1994589	17925851	LN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1994589	17925851	LN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1994589	17925851	LN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1994589	17925851	TH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1994589	17925851	TH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1994589	17925851	TH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1994589	17925851	TL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1994589	17925851	TL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1994589	17925851	TL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1994589	17925851	TL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1994589	17925851	TL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5826191	29515604	All authors	2	have contributed significantly to this work and analyzed the data	have contributed significantly to this work and analyzed the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5826191	29515604	CN	2	performed the experiments and collected the data	performed the experiments and collected the data	Performed the experiments	Investigation	YES
5826191	29515604	ES	2	designed the experiments|wrote the article with contributions from all authors	designed the experiments	Conceived and designed the experiments	Methodology	YES
5826191	29515604	ES	2	designed the experiments|wrote the article with contributions from all authors	wrote the article with contributions from all authors	Wrote the paper	Writing - Original Draft	YES
5826191	29515604	LV	2	performed the experiments and collected the data|wrote the article with contributions from all authors	performed the experiments and collected the data	Performed the experiments	Investigation	YES
5826191	29515604	LV	2	performed the experiments and collected the data|wrote the article with contributions from all authors	wrote the article with contributions from all authors	Wrote the paper	Writing - Original Draft	YES
5826191	29515604	MS	2	designed the experiments|wrote the article with contributions from all authors	designed the experiments	Conceived and designed the experiments	Methodology	YES
5826191	29515604	MS	2	designed the experiments|wrote the article with contributions from all authors	wrote the article with contributions from all authors	Wrote the paper	Writing - Original Draft	YES
4418665	25938482	AMY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418665	25938482	AMY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4418665	25938482	AMY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418665	25938482	FM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418665	25938482	GD	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418665	25938482	KB	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4418665	25938482	KB	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418665	25938482	MLM	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418665	25938482	MM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418665	25938482	MM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4418665	25938482	MM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418665	25938482	MVC	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418665	25938482	MVC	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418665	25938482	PG	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418665	25938482	PG	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418665	25938482	VI	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4418665	25938482	VI	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5352821	28289262	All authors	2	contributed to study conception and design and interpretation of the data, revised the article critically and approved the final version for publication	contributed to study conception and design and interpretation of the data, revised the article critically and approved the final version for publication	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Methodology|Resources|Writing - Review & Editing	YES
5352821	28289262	J.G.W.	2	developed the model|collected and analysed the data and drafted the article	developed the model	Performed the experiments	Methodology	YES
5352821	28289262	J.G.W.	2	developed the model|collected and analysed the data and drafted the article	collected and analysed the data and drafted the article	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5352821	28289262	M.P.	2	developed the model	developed the model	Performed the experiments	Methodology	YES
5352821	28289262	P.A.V.	2	developed the model	developed the model	Performed the experiments	Methodology	YES
6270817	25407721	G.B.	PLoS52	participated in the discussion of the results and writing of the manuscript	participated in the discussion of the results and writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
6270817	25407721	I.S.-B.	PLoS52	conceived of and designed the experiments, analyzed the data and wrote the manuscript	conceived of and designed the experiments, analyzed the data and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
6270817	25407721	S.G.	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5906417	29671176	All	2	data generated or analyzed during this study are included within the article|data published here are under consent for publication	data generated or analyzed during this study are included within the article	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5906417	29671176	All	2	data generated or analyzed during this study are included within the article|data published here are under consent for publication	data published here are under consent for publication	-	-	NO
5906417	29671176	All authors	2	gave intellectual input to the study|read and approved the final manuscript	gave intellectual input to the study	-	-	NO
5906417	29671176	All authors	2	gave intellectual input to the study|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5906417	29671176	JZW	2	collected and analyzed the data	collected and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5906417	29671176	LZ	2	collected and analyzed the data	collected and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5906417	29671176	QL	2	collected and analyzed the data|revised the manuscript critically for intellectual content	collected and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5906417	29671176	QL	2	collected and analyzed the data|revised the manuscript critically for intellectual content	revised the manuscript critically for intellectual content	Wrote the paper	Writing - Review & Editing	YES
5906417	29671176	QW	2	designed the study|collected and analyzed the data|revised the manuscript critically for intellectual content	designed the study	Conceived and designed the experiments	Methodology	YES
5906417	29671176	QW	2	designed the study|collected and analyzed the data|revised the manuscript critically for intellectual content	collected and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5906417	29671176	QW	2	designed the study|collected and analyzed the data|revised the manuscript critically for intellectual content	revised the manuscript critically for intellectual content	Wrote the paper	Writing - Review & Editing	YES
5906417	29671176	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5906417	29671176	WW	2	collected and analyzed the data	collected and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5906417	29671176	XGG	2	designed the study|collected and analyzed the data|drafted and wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5906417	29671176	XGG	2	designed the study|collected and analyzed the data|drafted and wrote the manuscript	collected and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5906417	29671176	XGG	2	designed the study|collected and analyzed the data|drafted and wrote the manuscript	drafted and wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5906417	29671176	YZZ	2	collected and analyzed the data|advised on data analysis	collected and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5906417	29671176	YZZ	2	collected and analyzed the data|advised on data analysis	advised on data analysis	Analyzed the data	Formal analysis	YES
4644821	26609533	Grace H. Lo	2	contributed to interpretation of data	contributed to interpretation of data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
4644821	26609533	Jeffrey B. Driban	2	contributed to the conception and design, acquisition of data, analysis and interpretation of data, drafting/revision of the paper, and final approval of the paper	contributed to the conception and design, acquisition of data, analysis and interpretation of data, drafting/revision of the paper, and final approval of the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
4644821	26609533	Lori Lyn Price	2	contributed to the conception and design, acquisition of data, analysis, interpretation of data, drafting/revision of the paper, and final approval of the paper	contributed to the conception and design, acquisition of data, analysis, interpretation of data, drafting/revision of the paper, and final approval of the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
4644821	26609533	Ming Zhang	2	contributed to the conception and design, acquisition of data, analysis, interpretation of data, drafting/revision of the paper, and final approval of the paper	contributed to the conception and design, acquisition of data, analysis, interpretation of data, drafting/revision of the paper, and final approval of the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Resources|Writing - Original Draft|Writing - Review & Editing	YES
4644821	26609533	Timothy E. Alindon	2	contributed to the conception and design, analysis and interpretation of data, drafting/revisions of the paper, and final approval of the paper	contributed to the conception and design, analysis and interpretation of data, drafting/revisions of the paper, and final approval of the paper	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5787233	29373957	CMS	PLoS52	conceived the study|processed the snp data	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5787233	29373957	CMS	PLoS52	conceived the study|processed the snp data	processed the snp data	Analyzed the data	Data curation	YES
5787233	29373957	MJ	PLoS52	conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5787233	29373957	PS	PLoS52	conceived the study|processed the snp data|wrote the computer scripts	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5787233	29373957	PS	PLoS52	conceived the study|processed the snp data|wrote the computer scripts	processed the snp data	Analyzed the data	Data curation	YES
5787233	29373957	PS	PLoS52	conceived the study|processed the snp data|wrote the computer scripts	wrote the computer scripts	Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Software|Writing - Original Draft	YES
5787233	29373957	TN	PLoS52	conceived the study|analysed the data	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5787233	29373957	TN	PLoS52	conceived the study|analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
1994590	17925852	AA	PLoS5	Experimental assistance	Experimental assistance	-	-	NO
1994590	17925852	HT	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1994590	17925852	KO	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1994590	17925852	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1994590	17925852	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1994590	17925852	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1994590	17925852	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1994590	17925852	SO	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1994590	17925852	SO	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1994590	17925852	SO	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5826214	29515603	HX	2	performed the research|analyzed the data and wrote the paper	performed the research	Performed the experiments	Investigation	YES
5826214	29515603	HX	2	performed the research|analyzed the data and wrote the paper	analyzed the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5826214	29515603	JX	2	designed the study|analyzed the data and wrote the paper	designed the study	Conceived and designed the experiments	Methodology	YES
5826214	29515603	JX	2	designed the study|analyzed the data and wrote the paper	analyzed the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5826214	29515603	LZ	2	performed the research	performed the research	Performed the experiments	Investigation	YES
5826214	29515603	RL	2	performed the research	performed the research	Performed the experiments	Investigation	YES
5826214	29515603	SL	2	performed the research	performed the research	Performed the experiments	Investigation	YES
5826214	29515603	XL	2	performed the research	performed the research	Performed the experiments	Investigation	YES
5826214	29515603	XW	2	performed the research	performed the research	Performed the experiments	Investigation	YES
5826214	29515603	YJ	2	discussed the results and made comments on the manuscript	discussed the results and made comments on the manuscript	-	-	NO
5352822	28289263	A.B.	2	conceived the project and designed the study	conceived the project and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5352822	28289263	All authors	2	contributed substantially to the analysis and interpretation of data and drafting the article	contributed substantially to the analysis and interpretation of data and drafting the article	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
5352822	28289263	H.C.L.	2	conceived the project and designed the study|performed the experiments, analysed the data and wrote the first draft of the article	conceived the project and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5352822	28289263	H.C.L.	2	conceived the project and designed the study|performed the experiments, analysed the data and wrote the first draft of the article	performed the experiments, analysed the data and wrote the first draft of the article	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3569650	23161805	CO	2	participated in design of the experiments and writing the manuscript	participated in design of the experiments and writing the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
3569650	23161805	DI	2	conceptualized and supervised the project|wrote the final version of the paper	conceptualized and supervised the project	Conceived and designed the experiments	Conceptualization|Supervision	YES
3569650	23161805	DI	2	conceptualized and supervised the project|wrote the final version of the paper	wrote the final version of the paper	Wrote the paper	Writing - Original Draft	YES
3569650	23161805	ES	2	wrote the final version of the paper	wrote the final version of the paper	Wrote the paper	Writing - Original Draft	YES
3569650	23161805	HP	2	collected and analysed the data|participated in design of the experiments and writing the manuscript	collected and analysed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3569650	23161805	HP	2	collected and analysed the data|participated in design of the experiments and writing the manuscript	participated in design of the experiments and writing the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
3569650	23161805	JT	2	collected and analysed the data	collected and analysed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3569650	23161805	LJ	2	collected and analysed the data	collected and analysed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3569650	23161805	PR	2	participated in design of the experiments and writing the manuscript	participated in design of the experiments and writing the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
3569650	23161805	RAB	2	collected and analysed the data	collected and analysed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3569650	23161805	RC	2	collected and analysed the data	collected and analysed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3569650	23161805	RV	2	participated in design of the experiments and writing the manuscript	participated in design of the experiments and writing the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
6270818	25100250	Lin Wang	2	took part in the extraction and isolation	took part in the extraction and isolation	Performed the experiments	Investigation	YES
6270818	25100250	Neng-Jiang Yu	2	was the project leader who took charge of the throughout research and accomplished writing of the paper	was the project leader who took charge of the throughout research and accomplished writing of the paper	Wrote the paper	Supervision|Writing - Original Draft	YES
6270818	25100250	Ruo-Feng Sun	2	took part in the extraction and isolation	took part in the extraction and isolation	Performed the experiments	Investigation	YES
6270818	25100250	Xiao-Ting Liu	2	achieved the whole experimental work, including isolation, purification, identification and prepared the manuscript	achieved the whole experimental work, including isolation, purification, identification and prepared the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4418666	25938434	FED	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418666	25938434	HMT	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418666	25938434	HNO	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418666	25938434	KH	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418666	25938434	KHM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418666	25938434	KK	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418666	25938434	KO	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418666	25938434	KT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418666	25938434	KT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418666	25938434	KT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418666	25938434	KT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418666	25938434	KU	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418666	25938434	KWH	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418666	25938434	KZT	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418666	25938434	MMW	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418666	25938434	MW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418666	25938434	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418666	25938434	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418666	25938434	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418666	25938434	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418666	25938434	SR	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418666	25938434	SVN	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418666	25938434	TH	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418666	25938434	TI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418666	25938434	TI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418666	25938434	TI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418666	25938434	TI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418666	25938434	TT	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418666	25938434	TWM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418666	25938434	YF	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418666	25938434	YYM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5826215	29515611	The authors	2	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	Performed the experiments	Investigation	YES
5787247	29373972	AG	2	conceptualised the study and drafted the manuscript	conceptualised the study and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5787247	29373972	AHT	2	developed the transcriptome databases and performed the bioinformatic analyses	developed the transcriptome databases and performed the bioinformatic analyses	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Software	YES
5787247	29373972	BS	2	developed the transcriptome databases and performed the bioinformatic analyses	developed the transcriptome databases and performed the bioinformatic analyses	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Software	YES
5787247	29373972	RDN	2	conceptualised the study and drafted the manuscript	conceptualised the study and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5906420	29671147	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5906420	29671147	FS	2	conceived and designed the experiments, coordinated the study, analyzed the data and contributed to the writing of the manuscript	conceived and designed the experiments, coordinated the study, analyzed the data and contributed to the writing of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Project administration|Writing - Original Draft	YES
5906420	29671147	ML	2	performed the measurements and experiments and analyzed the data	performed the measurements and experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5906420	29671147	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5906420	29671147	YL	2	participated in the writing of the manuscript	participated in the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
1994591	17925854	AB	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1994591	17925854	AB	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1994591	17925854	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1994591	17925854	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1994591	17925854	AM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1994591	17925854	CG	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1994591	17925854	CG	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1994591	17925854	CM	PLoS5	Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1994591	17925854	CM	PLoS5	Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1994591	17925854	CM	PLoS5	Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1994591	17925854	CM	PLoS5	Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1994591	17925854	CM	PLoS5	Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1994591	17925854	DC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1994591	17925854	DC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1994591	17925854	DC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1994591	17925854	FC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1994591	17925854	FC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1994591	17925854	FC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1994591	17925854	JM	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1994591	17925854	JM	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1994591	17925854	MB	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1994591	17925854	MB	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
3569651	23239665	AS	PLoS52	performed in vitro assays	performed in vitro assays	Performed the experiments	Investigation	YES
3569651	23239665	BD	PLoS52	designed the experiments|analysed the data|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
3569651	23239665	BD	PLoS52	designed the experiments|analysed the data|wrote the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
3569651	23239665	BD	PLoS52	designed the experiments|analysed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3569651	23239665	EF	PLoS52	performed immunohistochemical staining	performed immunohistochemical staining	Performed the experiments	Investigation	YES
3569651	23239665	ERG	PLoS52	provided the surgical samples	provided the surgical samples	Contributed reagents/materials/analysis tools	Resources	YES
3569651	23239665	KM	PLoS52	performed immunohistochemical staining	performed immunohistochemical staining	Performed the experiments	Investigation	YES
3569651	23239665	MMD	PLoS52	performed the in vivo experiments	performed the in vivo experiments	Performed the experiments	Investigation	YES
3569651	23239665	NPS	PLoS52	designed the experiments|performed the in vivo experiments|performed in vitro assays|analysed the data|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
3569651	23239665	NPS	PLoS52	designed the experiments|performed the in vivo experiments|performed in vitro assays|analysed the data|wrote the manuscript	performed the in vivo experiments	Performed the experiments	Investigation	YES
3569651	23239665	NPS	PLoS52	designed the experiments|performed the in vivo experiments|performed in vitro assays|analysed the data|wrote the manuscript	performed in vitro assays	Performed the experiments	Investigation	YES
3569651	23239665	NPS	PLoS52	designed the experiments|performed the in vivo experiments|performed in vitro assays|analysed the data|wrote the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
3569651	23239665	NPS	PLoS52	designed the experiments|performed the in vivo experiments|performed in vitro assays|analysed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3569651	23239665	OHS	PLoS52	performed in vitro assays	performed in vitro assays	Performed the experiments	Investigation	YES
3569651	23239665	PT	PLoS52	performed in vitro assays	performed in vitro assays	Performed the experiments	Investigation	YES
3569651	23239665	RS	PLoS52	performed the in vivo experiments|performed in vitro assays|analysed the data|performed immunohistochemical staining|wrote the manuscript	performed the in vivo experiments	Performed the experiments	Investigation	YES
3569651	23239665	RS	PLoS52	performed the in vivo experiments|performed in vitro assays|analysed the data|performed immunohistochemical staining|wrote the manuscript	performed in vitro assays	Performed the experiments	Investigation	YES
3569651	23239665	RS	PLoS52	performed the in vivo experiments|performed in vitro assays|analysed the data|performed immunohistochemical staining|wrote the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
3569651	23239665	RS	PLoS52	performed the in vivo experiments|performed in vitro assays|analysed the data|performed immunohistochemical staining|wrote the manuscript	performed immunohistochemical staining	Performed the experiments	Investigation	YES
3569651	23239665	RS	PLoS52	performed the in vivo experiments|performed in vitro assays|analysed the data|performed immunohistochemical staining|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3569651	23239665	RSG	PLoS52	analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
3569651	23239665	SB	PLoS52	performed the in vivo experiments|performed in vitro assays	performed the in vivo experiments	Performed the experiments	Investigation	YES
3569651	23239665	SB	PLoS52	performed the in vivo experiments|performed in vitro assays	performed in vitro assays	Performed the experiments	Investigation	YES
3569651	23239665	SPC	PLoS52	performed the in vivo experiments	performed the in vivo experiments	Performed the experiments	Investigation	YES
3569651	23239665	VSS	PLoS52	analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
3569651	23239665	YM	PLoS52	provided the surgical samples	provided the surgical samples	Contributed reagents/materials/analysis tools	Resources	YES
4418667	25938234	CNK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Conducted and analyzed cell based assays|Designed, conducted the study, analyzed the data and wrote the first draft|Supervised entire research work|Edited and approved the final version of manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418667	25938234	CNK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Conducted and analyzed cell based assays|Designed, conducted the study, analyzed the data and wrote the first draft|Supervised entire research work|Edited and approved the final version of manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418667	25938234	CNK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Conducted and analyzed cell based assays|Designed, conducted the study, analyzed the data and wrote the first draft|Supervised entire research work|Edited and approved the final version of manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418667	25938234	CNK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Conducted and analyzed cell based assays|Designed, conducted the study, analyzed the data and wrote the first draft|Supervised entire research work|Edited and approved the final version of manuscript	Conducted and analyzed cell based assays	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4418667	25938234	CNK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Conducted and analyzed cell based assays|Designed, conducted the study, analyzed the data and wrote the first draft|Supervised entire research work|Edited and approved the final version of manuscript	Designed, conducted the study, analyzed the data and wrote the first draft	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4418667	25938234	CNK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Conducted and analyzed cell based assays|Designed, conducted the study, analyzed the data and wrote the first draft|Supervised entire research work|Edited and approved the final version of manuscript	Supervised entire research work	Performed the experiments	Investigation|Supervision	YES
4418667	25938234	CNK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Conducted and analyzed cell based assays|Designed, conducted the study, analyzed the data and wrote the first draft|Supervised entire research work|Edited and approved the final version of manuscript	Edited and approved the final version of manuscript	Wrote the paper	Writing - Review & Editing	YES
4418667	25938234	CRP	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Designed and overseen the in-silico study|Designed, conducted the study, analyzed the data and wrote the first draft|Supervised entire research work|Edited and approved the final version of manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418667	25938234	CRP	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Designed and overseen the in-silico study|Designed, conducted the study, analyzed the data and wrote the first draft|Supervised entire research work|Edited and approved the final version of manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4418667	25938234	CRP	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Designed and overseen the in-silico study|Designed, conducted the study, analyzed the data and wrote the first draft|Supervised entire research work|Edited and approved the final version of manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418667	25938234	CRP	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Designed and overseen the in-silico study|Designed, conducted the study, analyzed the data and wrote the first draft|Supervised entire research work|Edited and approved the final version of manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418667	25938234	CRP	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Designed and overseen the in-silico study|Designed, conducted the study, analyzed the data and wrote the first draft|Supervised entire research work|Edited and approved the final version of manuscript	Designed and overseen the in-silico study	Conceived and designed the experiments	Formal analysis|Methodology|Supervision	YES
4418667	25938234	CRP	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Designed and overseen the in-silico study|Designed, conducted the study, analyzed the data and wrote the first draft|Supervised entire research work|Edited and approved the final version of manuscript	Designed, conducted the study, analyzed the data and wrote the first draft	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4418667	25938234	CRP	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Designed and overseen the in-silico study|Designed, conducted the study, analyzed the data and wrote the first draft|Supervised entire research work|Edited and approved the final version of manuscript	Supervised entire research work	Performed the experiments	Investigation|Supervision	YES
4418667	25938234	CRP	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Designed and overseen the in-silico study|Designed, conducted the study, analyzed the data and wrote the first draft|Supervised entire research work|Edited and approved the final version of manuscript	Edited and approved the final version of manuscript	Wrote the paper	Writing - Review & Editing	YES
4418667	25938234	HMP	PLoS5	Analyzed the data|Wrote the paper|Designed and overseen the in-silico study|Analyzed the data|Collected references and drafted the manuscript|Edited and approved the final version of manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4418667	25938234	HMP	PLoS5	Analyzed the data|Wrote the paper|Designed and overseen the in-silico study|Analyzed the data|Collected references and drafted the manuscript|Edited and approved the final version of manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418667	25938234	HMP	PLoS5	Analyzed the data|Wrote the paper|Designed and overseen the in-silico study|Analyzed the data|Collected references and drafted the manuscript|Edited and approved the final version of manuscript	Designed and overseen the in-silico study	Conceived and designed the experiments	Formal analysis|Methodology|Supervision	YES
4418667	25938234	HMP	PLoS5	Analyzed the data|Wrote the paper|Designed and overseen the in-silico study|Analyzed the data|Collected references and drafted the manuscript|Edited and approved the final version of manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4418667	25938234	HMP	PLoS5	Analyzed the data|Wrote the paper|Designed and overseen the in-silico study|Analyzed the data|Collected references and drafted the manuscript|Edited and approved the final version of manuscript	Collected references and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4418667	25938234	HMP	PLoS5	Analyzed the data|Wrote the paper|Designed and overseen the in-silico study|Analyzed the data|Collected references and drafted the manuscript|Edited and approved the final version of manuscript	Edited and approved the final version of manuscript	Wrote the paper	Writing - Review & Editing	YES
4418667	25938234	KRP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Conducted and analyzed cell based assays|Designed and overseen the in-silico study|Analyzed the data|Designed, conducted the study, analyzed the data and wrote the first draft|Collected references and drafted the manuscript|Edited and approved the final version of manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418667	25938234	KRP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Conducted and analyzed cell based assays|Designed and overseen the in-silico study|Analyzed the data|Designed, conducted the study, analyzed the data and wrote the first draft|Collected references and drafted the manuscript|Edited and approved the final version of manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4418667	25938234	KRP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Conducted and analyzed cell based assays|Designed and overseen the in-silico study|Analyzed the data|Designed, conducted the study, analyzed the data and wrote the first draft|Collected references and drafted the manuscript|Edited and approved the final version of manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4418667	25938234	KRP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Conducted and analyzed cell based assays|Designed and overseen the in-silico study|Analyzed the data|Designed, conducted the study, analyzed the data and wrote the first draft|Collected references and drafted the manuscript|Edited and approved the final version of manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418667	25938234	KRP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Conducted and analyzed cell based assays|Designed and overseen the in-silico study|Analyzed the data|Designed, conducted the study, analyzed the data and wrote the first draft|Collected references and drafted the manuscript|Edited and approved the final version of manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418667	25938234	KRP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Conducted and analyzed cell based assays|Designed and overseen the in-silico study|Analyzed the data|Designed, conducted the study, analyzed the data and wrote the first draft|Collected references and drafted the manuscript|Edited and approved the final version of manuscript	Conducted and analyzed cell based assays	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4418667	25938234	KRP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Conducted and analyzed cell based assays|Designed and overseen the in-silico study|Analyzed the data|Designed, conducted the study, analyzed the data and wrote the first draft|Collected references and drafted the manuscript|Edited and approved the final version of manuscript	Designed and overseen the in-silico study	Conceived and designed the experiments	Formal analysis|Methodology|Supervision	YES
4418667	25938234	KRP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Conducted and analyzed cell based assays|Designed and overseen the in-silico study|Analyzed the data|Designed, conducted the study, analyzed the data and wrote the first draft|Collected references and drafted the manuscript|Edited and approved the final version of manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4418667	25938234	KRP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Conducted and analyzed cell based assays|Designed and overseen the in-silico study|Analyzed the data|Designed, conducted the study, analyzed the data and wrote the first draft|Collected references and drafted the manuscript|Edited and approved the final version of manuscript	Designed, conducted the study, analyzed the data and wrote the first draft	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4418667	25938234	KRP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Conducted and analyzed cell based assays|Designed and overseen the in-silico study|Analyzed the data|Designed, conducted the study, analyzed the data and wrote the first draft|Collected references and drafted the manuscript|Edited and approved the final version of manuscript	Collected references and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4418667	25938234	KRP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Conducted and analyzed cell based assays|Designed and overseen the in-silico study|Analyzed the data|Designed, conducted the study, analyzed the data and wrote the first draft|Collected references and drafted the manuscript|Edited and approved the final version of manuscript	Edited and approved the final version of manuscript	Wrote the paper	Writing - Review & Editing	YES
4418667	25938234	PM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Conducted and analyzed cell based assays|Analyzed the data|Collected references and drafted the manuscript|Edited and approved the final version of manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4418667	25938234	PM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Conducted and analyzed cell based assays|Analyzed the data|Collected references and drafted the manuscript|Edited and approved the final version of manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4418667	25938234	PM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Conducted and analyzed cell based assays|Analyzed the data|Collected references and drafted the manuscript|Edited and approved the final version of manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418667	25938234	PM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Conducted and analyzed cell based assays|Analyzed the data|Collected references and drafted the manuscript|Edited and approved the final version of manuscript	Conducted and analyzed cell based assays	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4418667	25938234	PM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Conducted and analyzed cell based assays|Analyzed the data|Collected references and drafted the manuscript|Edited and approved the final version of manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4418667	25938234	PM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Conducted and analyzed cell based assays|Analyzed the data|Collected references and drafted the manuscript|Edited and approved the final version of manuscript	Collected references and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4418667	25938234	PM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Conducted and analyzed cell based assays|Analyzed the data|Collected references and drafted the manuscript|Edited and approved the final version of manuscript	Edited and approved the final version of manuscript	Wrote the paper	Writing - Review & Editing	YES
4418667	25938234	SNG	PLoS5	Analyzed the data|Wrote the paper|Analyzed the data|Supervised entire research work|Collected references and drafted the manuscript|Edited and approved the final version of manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4418667	25938234	SNG	PLoS5	Analyzed the data|Wrote the paper|Analyzed the data|Supervised entire research work|Collected references and drafted the manuscript|Edited and approved the final version of manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418667	25938234	SNG	PLoS5	Analyzed the data|Wrote the paper|Analyzed the data|Supervised entire research work|Collected references and drafted the manuscript|Edited and approved the final version of manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4418667	25938234	SNG	PLoS5	Analyzed the data|Wrote the paper|Analyzed the data|Supervised entire research work|Collected references and drafted the manuscript|Edited and approved the final version of manuscript	Supervised entire research work	Performed the experiments	Investigation|Supervision	YES
4418667	25938234	SNG	PLoS5	Analyzed the data|Wrote the paper|Analyzed the data|Supervised entire research work|Collected references and drafted the manuscript|Edited and approved the final version of manuscript	Collected references and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4418667	25938234	SNG	PLoS5	Analyzed the data|Wrote the paper|Analyzed the data|Supervised entire research work|Collected references and drafted the manuscript|Edited and approved the final version of manuscript	Edited and approved the final version of manuscript	Wrote the paper	Writing - Review & Editing	YES
4418667	25938234	SO	PLoS5	Analyzed the data|Wrote the paper|Analyzed the data|Collected references and drafted the manuscript|Edited and approved the final version of manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4418667	25938234	SO	PLoS5	Analyzed the data|Wrote the paper|Analyzed the data|Collected references and drafted the manuscript|Edited and approved the final version of manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418667	25938234	SO	PLoS5	Analyzed the data|Wrote the paper|Analyzed the data|Collected references and drafted the manuscript|Edited and approved the final version of manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4418667	25938234	SO	PLoS5	Analyzed the data|Wrote the paper|Analyzed the data|Collected references and drafted the manuscript|Edited and approved the final version of manuscript	Collected references and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4418667	25938234	SO	PLoS5	Analyzed the data|Wrote the paper|Analyzed the data|Collected references and drafted the manuscript|Edited and approved the final version of manuscript	Edited and approved the final version of manuscript	Wrote the paper	Writing - Review & Editing	YES
4644829	26609535	Chih-Hsi Kuo	2	helped to enroll the patients and analyzed the data	helped to enroll the patients and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4644829	26609535	Chih-Teng Yu	2	helped to enroll the patients and analyzed the data	helped to enroll the patients and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4644829	26609535	Chun-Hwa Wang	2	helped to enroll the patients and analyzed the data	helped to enroll the patients and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4644829	26609535	Fu-Tsai Chung	2	conceived, designed, and performed the study, analyzed the data, and wrote the paper|contributed equally to the work on this project as first authors	conceived, designed, and performed the study, analyzed the data, and wrote the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4644829	26609535	Fu-Tsai Chung	2	conceived, designed, and performed the study, analyzed the data, and wrote the paper|contributed equally to the work on this project as first authors	contributed equally to the work on this project as first authors	-	-	NO
4644829	26609535	Han-Pin Kuo	2	conceived, designed, and performed the study, analyzed the data, and wrote the paper	conceived, designed, and performed the study, analyzed the data, and wrote the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4644829	26609535	Hao-Cheng Chen	2	helped to enroll the patients and analyzed the data	helped to enroll the patients and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4644829	26609535	Horng-Chyuan Lin	2	helped to enroll the patients and analyzed the data	helped to enroll the patients and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4644829	26609535	Meng-Heng Hshieh	2	helped to enroll the patients and analyzed the data	helped to enroll the patients and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4644829	26609535	Ming-Yun Ho	2	conceived, designed, and performed the study, analyzed the data, and wrote the paper|contributed equally to the work on this project as first authors	conceived, designed, and performed the study, analyzed the data, and wrote the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4644829	26609535	Ming-Yun Ho	2	conceived, designed, and performed the study, analyzed the data, and wrote the paper|contributed equally to the work on this project as first authors	contributed equally to the work on this project as first authors	-	-	NO
4644829	26609535	Shu-Min Lin	2	helped to enroll the patients and analyzed the data	helped to enroll the patients and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4644829	26609535	Tsai-Yu Wang	2	helped to enroll the patients and analyzed the data	helped to enroll the patients and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4644829	26609535	Yueh-Fu Fang	2	helped to enroll the patients and analyzed the data	helped to enroll the patients and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270820	24905605	Alejandra Moenne	2	designed experiments and wrote the manuscript	designed experiments and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5379027	28348255	K.B.	2	conceived of the theory and wrote the manuscript	conceived of the theory and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5379027	28348255	S.C.	2	surveyed the literature	surveyed the literature	Performed the experiments	Investigation	YES
5826225	29515602	AB	1	Phenotyping for kernel quality	Phenotyping for kernel quality	Performed the experiments	Investigation	YES
5826225	29515602	FH	1	Development of segregating progenies|Morphological characterization|Statistical analyses|Drafting of the manuscript|Designing of the experiment	Development of segregating progenies	-	-	NO
5826225	29515602	FH	1	Development of segregating progenies|Morphological characterization|Statistical analyses|Drafting of the manuscript|Designing of the experiment	Morphological characterization	Performed the experiments	Investigation	YES
5826225	29515602	FH	1	Development of segregating progenies|Morphological characterization|Statistical analyses|Drafting of the manuscript|Designing of the experiment	Statistical analyses	Analyzed the data	Formal analysis	YES
5826225	29515602	FH	1	Development of segregating progenies|Morphological characterization|Statistical analyses|Drafting of the manuscript|Designing of the experiment	Drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
5826225	29515602	FH	1	Development of segregating progenies|Morphological characterization|Statistical analyses|Drafting of the manuscript|Designing of the experiment	Designing of the experiment	Conceived and designed the experiments	Methodology	YES
5826225	29515602	HC	1	Analysis on kernel modification	Analysis on kernel modification	-	-	NO
5826225	29515602	HG	1	Designing of the experiment	Designing of the experiment	Conceived and designed the experiments	Methodology	YES
5826225	29515602	JB	1	Morphological characterization	Morphological characterization	Performed the experiments	Investigation	YES
5826225	29515602	NT	1	Statistical analyses	Statistical analyses	Analyzed the data	Formal analysis	YES
5826225	29515602	RZ	1	Conduct of all experiments|Drafting of the manuscript	Conduct of all experiments	Performed the experiments	Investigation	YES
5826225	29515602	RZ	1	Conduct of all experiments|Drafting of the manuscript	Drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
5826225	29515602	SS	1	Phenotyping for kernel quality	Phenotyping for kernel quality	Performed the experiments	Investigation	YES
5826225	29515602	VM	1	Development of segregating progenies|Phenotyping for kernel quality	Development of segregating progenies	-	-	NO
5826225	29515602	VM	1	Development of segregating progenies|Phenotyping for kernel quality	Phenotyping for kernel quality	Performed the experiments	Investigation	YES
5787291	29373953	A.P.S.	PLoS52	conceived and designed the experiments|analyzed the data|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5787291	29373953	A.P.S.	PLoS52	conceived and designed the experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5787291	29373953	A.P.S.	PLoS52	conceived and designed the experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5787291	29373953	D.O.	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5787291	29373953	M.D.	PLoS52	conceived and designed the experiments|analyzed the data	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5787291	29373953	M.D.	PLoS52	conceived and designed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5787291	29373953	M.V.R.	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5787291	29373953	N.B.	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5787291	29373953	Q.Z.	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5787291	29373953	Q.Z.	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5787291	29373953	Q.Z.	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5787291	29373953	Q.Z.	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5787291	29373953	S.F.D.	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
1994592	17912368	AA	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1994592	17912368	AA	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1994592	17912368	AA	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1994592	17912368	AS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1994592	17912368	AS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1994592	17912368	AZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1994592	17912368	AZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1994592	17912368	AZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1994592	17912368	BR	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1994592	17912368	BR	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1994592	17912368	EP	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1994592	17912368	EP	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1994592	17912368	EP	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1994592	17912368	JP	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1994592	17912368	JP	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1994592	17912368	MT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1994592	17912368	MT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1994592	17912368	MT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1994592	17912368	TD	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418668	25938773	JAD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418668	25938773	JAD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418668	25938773	JAD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418668	25938773	JWP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418668	25938773	JWP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418668	25938773	JWP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418668	25938773	JWP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418668	25938773	NSG	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4418668	25938773	NSG	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418668	25938773	QY	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418668	25938773	QY	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418668	25938773	QY	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418668	25938773	TM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418668	25938773	TM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418668	25938773	TM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418668	25938773	TRB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418668	25938773	TRB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418668	25938773	TRB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418668	25938773	VM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4418668	25938773	VM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
3569652	23229821	AGH	2	designed and supervised the research project, and revised the manuscript	designed and supervised the research project, and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Review & Editing	YES
3569652	23229821	DW	2	performed the bioinformatics analyses and wrote the manuscript	performed the bioinformatics analyses and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3569652	23229821	JI	2	designed and supervised the research project, and revised the manuscript	designed and supervised the research project, and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Review & Editing	YES
3569652	23229821	JV	2	designed and supervised the research project, and revised the manuscript	designed and supervised the research project, and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Review & Editing	YES
3569652	23229821	KR	2	performed the experiments, analysed the data, and wrote the manuscript	performed the experiments, analysed the data, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3569652	23229821	KW	2	performed the experiments, analysed the data, and wrote the manuscript	performed the experiments, analysed the data, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3569652	23229821	MLdB	2	provided patient samples, clinical data and revised the manuscript	provided patient samples, clinical data and revised the manuscript	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Review & Editing	YES
3569652	23229821	MSch	2	provided patient samples, clinical data and revised the manuscript	provided patient samples, clinical data and revised the manuscript	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Review & Editing	YES
3569652	23229821	MSt	2	provided patient samples, clinical data and revised the manuscript	provided patient samples, clinical data and revised the manuscript	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Review & Editing	YES
3569652	23229821	OH	2	designed and supervised the research project, and revised the manuscript	designed and supervised the research project, and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Review & Editing	YES
3569652	23229821	SB	2	performed the experiments, analysed the data, and wrote the manuscript	performed the experiments, analysed the data, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4644933	26609523	Song Li	2	contributed equally to this work	contributed equally to this work	-	-	NO
4644933	26609523	Yufa Zhou	2	contributed equally to this work	contributed equally to this work	-	-	NO
4644933	26609523	Yuxin Zhao	2	contributed equally to this work	contributed equally to this work	-	-	NO
5906421	29671083	AE	PLoS52	made a substantial contribution to the analysis and interpretation of the data presented|made a substantial contribution to the analysis and interpretation of the data presented	made a substantial contribution to the analysis and interpretation of the data presented	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5906421	29671083	AE	PLoS52	made a substantial contribution to the analysis and interpretation of the data presented|made a substantial contribution to the analysis and interpretation of the data presented	made a substantial contribution to the analysis and interpretation of the data presented	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5906421	29671083	AT	PLoS52	carried out experiments|conceived and designed the experiments|wrote the paper|conceived and designed the experiments|performed the experiments	carried out experiments	Performed the experiments	Investigation	YES
5906421	29671083	AT	PLoS52	carried out experiments|conceived and designed the experiments|wrote the paper|conceived and designed the experiments|performed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5906421	29671083	AT	PLoS52	carried out experiments|conceived and designed the experiments|wrote the paper|conceived and designed the experiments|performed the experiments	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5906421	29671083	AT	PLoS52	carried out experiments|conceived and designed the experiments|wrote the paper|conceived and designed the experiments|performed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5906421	29671083	AT	PLoS52	carried out experiments|conceived and designed the experiments|wrote the paper|conceived and designed the experiments|performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5906421	29671083	Acknowledge	PLoS52	the school of public health bam, for providing the materials and laboratory equipment used in this study	the school of public health bam, for providing the materials and laboratory equipment used in this study	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5906421	29671083	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5906421	29671083	MA	PLoS52	made a substantial contribution to the analysis and interpretation of the data presented|made a substantial contribution to the analysis and interpretation of the data presented	made a substantial contribution to the analysis and interpretation of the data presented	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5906421	29671083	MA	PLoS52	made a substantial contribution to the analysis and interpretation of the data presented|made a substantial contribution to the analysis and interpretation of the data presented	made a substantial contribution to the analysis and interpretation of the data presented	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5906421	29671083	MAS	PLoS52	made a substantial contribution to the analysis and interpretation of the data presented	made a substantial contribution to the analysis and interpretation of the data presented	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5906421	29671083	MHE	PLoS52	wrote the paper|conceived and designed the experiments	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5906421	29671083	MHE	PLoS52	wrote the paper|conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5906421	29671083	MM	PLoS52	carried out experiments|conceived and designed the experiments	carried out experiments	Performed the experiments	Investigation	YES
5906421	29671083	MM	PLoS52	carried out experiments|conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5906421	29671083	MT	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5906421	29671083	MTG	PLoS52	carried out experiments|conceived and designed the experiments|wrote the paper	carried out experiments	Performed the experiments	Investigation	YES
5906421	29671083	MTG	PLoS52	carried out experiments|conceived and designed the experiments|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5906421	29671083	MTG	PLoS52	carried out experiments|conceived and designed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5906421	29671083	The authors	PLoS52	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5826256	29515599	DC-R	2	conducted screening and genetics crosses and performed all of the molecular work on the project	conducted screening and genetics crosses and performed all of the molecular work on the project	Performed the experiments	Investigation	YES
5826256	29515599	EW	2	conceived the project, was responsible for the experimental design, and also performed some of the genetics crosses and phenotyping in the field	conceived the project, was responsible for the experimental design, and also performed some of the genetics crosses and phenotyping in the field	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
4418669	25938725	HS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418669	25938725	WN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418669	25938725	WN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418669	25938725	WN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418669	25938725	WN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418669	25938725	XY	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418669	25938725	YJ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5789529	29378509	BTZ	2	searched the data and participated in the statistical analysis	searched the data and participated in the statistical analysis	Analyzed the data	Formal analysis	YES
5789529	29378509	HC	2	searched the data and participated in the statistical analysis	searched the data and participated in the statistical analysis	Analyzed the data	Formal analysis	YES
5789529	29378509	HDY	2	conceived the study, analysed the data, made figures, performed the statistical analysis, and drafted the manuscript	conceived the study, analysed the data, made figures, performed the statistical analysis, and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Visualization|Writing - Original Draft	YES
5789529	29378509	HPL	2	searched the data and participated in the statistical analysis	searched the data and participated in the statistical analysis	Analyzed the data	Formal analysis	YES
5789529	29378509	JH	2	searched the data and participated in the statistical analysis	searched the data and participated in the statistical analysis	Analyzed the data	Formal analysis	YES
5789529	29378509	KS	2	searched the data and participated in the statistical analysis	searched the data and participated in the statistical analysis	Analyzed the data	Formal analysis	YES
5789529	29378509	LA	2	participated in discussing and revising the manuscript	participated in discussing and revising the manuscript	Wrote the paper	Writing - Review & Editing	YES
5789529	29378509	QZG	2	conceived the study, analysed the data, made figures, performed the statistical analysis, and drafted the manuscript	conceived the study, analysed the data, made figures, performed the statistical analysis, and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Visualization|Writing - Original Draft	YES
5789529	29378509	WYZ	2	participated in discussing and revising the manuscript	participated in discussing and revising the manuscript	Wrote the paper	Writing - Review & Editing	YES
5789529	29378509	XLW	2	conceived of the study, and participated in its design and coordination, helped to draft the manuscript and supervised the work	conceived of the study, and participated in its design and coordination, helped to draft the manuscript and supervised the work	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Supervision|Writing - Original Draft	YES
5789529	29378509	YG	2	searched the data and participated in the statistical analysis	searched the data and participated in the statistical analysis	Analyzed the data	Formal analysis	YES
5789529	29378509	YHC	2	conceived the study, analysed the data, made figures, performed the statistical analysis, and drafted the manuscript	conceived the study, analysed the data, made figures, performed the statistical analysis, and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Visualization|Writing - Original Draft	YES
5789529	29378509	ZG	2	conceived of the study, and participated in its design and coordination, helped to draft the manuscript and supervised the work	conceived of the study, and participated in its design and coordination, helped to draft the manuscript and supervised the work	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Supervision|Writing - Original Draft	YES
5379028	28348256	All authors	2	contributed to the conception, drafting, figures and editing of the manuscript	contributed to the conception, drafting, figures and editing of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Visualization|Writing - Original Draft|Writing - Review & Editing	YES
6270821	25350363	H.B.	2	designed chemical experiments and analyzed chemical and biological assays	designed chemical experiments and analyzed chemical and biological assays	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
6270821	25350363	P.R.C.	2	performed biological assays and analyzed data	performed biological assays and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270821	25350363	R.G.S.	2	designed biological assays and analyzed biological data	designed biological assays and analyzed biological data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
1994593	17925855	BV	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1994593	17925855	BV	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1994593	17925855	BV	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1994593	17925855	BV	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1994593	17925855	BV	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1994593	17925855	CB	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1994593	17925855	CB	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1994593	17925855	CB	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1994593	17925855	CE	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1994593	17925855	CF	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1994593	17925855	CF	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1994593	17925855	CF	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1994593	17925855	IC	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1994593	17925855	IC	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1994593	17925855	JC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1994593	17925855	JC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1994593	17925855	KK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1994593	17925855	KK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1994593	17925855	KK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1994593	17925855	KT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1994593	17925855	KT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1994593	17925855	KT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1994593	17925855	KT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1994593	17925855	LD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Enrolled patients	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1994593	17925855	LD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Enrolled patients	Performed the experiments	Performed the experiments	Investigation	YES
1994593	17925855	LD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Enrolled patients	Analyzed the data	Analyzed the data	Formal analysis	YES
1994593	17925855	LD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Enrolled patients	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1994593	17925855	LD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Enrolled patients	Enrolled patients	Performed the experiments	Investigation	YES
1994593	17925855	MM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1994593	17925855	MM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1994593	17925855	MM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1994593	17925855	MM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1994593	17925855	MM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1994593	17925855	MP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1994593	17925855	MP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1994593	17925855	MP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1994593	17925855	NA	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1994593	17925855	OU	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1994593	17925855	PL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1994593	17925855	PL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1994593	17925855	SN	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1994593	17925855	SN	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1994593	17925855	SU	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1994593	17925855	SU	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1994593	17925855	SZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1994593	17925855	SZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1994593	17925855	SZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1994593	17925855	TS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1994593	17925855	TS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1994593	17925855	XZ	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1994593	17925855	XZ	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5826264	29515614	CHK	2	conceived the idea and designed the outlines of the article|revised the article	conceived the idea and designed the outlines of the article	Conceived and designed the experiments	Conceptualization	YES
5826264	29515614	CHK	2	conceived the idea and designed the outlines of the article|revised the article	revised the article	Wrote the paper	Writing - Review & Editing	YES
5826264	29515614	ESL	2	wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
5826264	29515614	GN	2	conceived the idea and designed the outlines of the article|wrote the article|revised the article	conceived the idea and designed the outlines of the article	Conceived and designed the experiments	Conceptualization	YES
5826264	29515614	GN	2	conceived the idea and designed the outlines of the article|wrote the article|revised the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
5826264	29515614	GN	2	conceived the idea and designed the outlines of the article|wrote the article|revised the article	revised the article	Wrote the paper	Writing - Review & Editing	YES
5826264	29515614	JHP	2	wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
5826264	29515614	RS	2	wrote the article|revised the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
5826264	29515614	RS	2	wrote the article|revised the article	revised the article	Wrote the paper	Writing - Review & Editing	YES
5826264	29515614	SWR	2	wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
5826264	29515614	SYL	2	conceived the idea and designed the outlines of the article|revised the article	conceived the idea and designed the outlines of the article	Conceived and designed the experiments	Conceptualization	YES
5826264	29515614	SYL	2	conceived the idea and designed the outlines of the article|revised the article	revised the article	Wrote the paper	Writing - Review & Editing	YES
5379030	28348258	All authors	2	contributed equally to the writing of the review	contributed equally to the writing of the review	Wrote the paper	Writing - Review & Editing	YES
4418671	25938509	AB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418671	25938509	AB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418671	25938509	AB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418671	25938509	AF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418671	25938509	AF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418671	25938509	AF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418671	25938509	AF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418671	25938509	BRM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418671	25938509	BRM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418671	25938509	BRM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418671	25938509	EM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418671	25938509	EM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418671	25938509	EM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418671	25938509	JAB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418671	25938509	JAB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418671	25938509	JAB	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418671	25938509	MMA	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418671	25938509	MMA	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418671	25938509	MMA	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418671	25938509	MPV	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418671	25938509	MPV	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418671	25938509	MPV	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418671	25938509	MRV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418671	25938509	MRV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418671	25938509	MRV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418671	25938509	MRV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418671	25938509	PMP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418671	25938509	PMP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418671	25938509	PMP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418671	25938509	PMP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418671	25938509	SCC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418671	25938509	SCC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418671	25938509	SCC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418671	25938509	SCC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3569653	23184605	AF	2	conceived the project and wrote the manuscript	conceived the project and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
3569653	23184605	FB	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
3569653	23184605	FS	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
3569653	23184605	JL	2	generated the hdac6 mouse model	generated the hdac6 mouse model	Performed the experiments	Investigation|Methodology	YES
3569653	23184605	NG	2	conceived the project and wrote the manuscript|performed most of the experimental work	conceived the project and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
3569653	23184605	NG	2	conceived the project and wrote the manuscript|performed most of the experimental work	performed most of the experimental work	Performed the experiments	Investigation	YES
3569653	23184605	OMS	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
3569653	23184605	PR	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
3569653	23184605	SB	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
1995752	17925870	CA	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1995752	17925870	CA	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1995752	17925870	CA	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1995752	17925870	CA	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1995752	17925870	DC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1995752	17925870	GP	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1995752	17925870	SK	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1995752	17925870	SK	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5910442	29679179	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5910442	29679179	CDW	2	performed experiments|wrote the manuscript	performed experiments	Performed the experiments	Investigation	YES
5910442	29679179	CDW	2	performed experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5910442	29679179	CJ	2	reviewed polished the paper	reviewed polished the paper	Wrote the paper	Writing - Review & Editing	YES
5910442	29679179	CQW	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5910442	29679179	JFD	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5910442	29679179	JKS	2	analyzed the data, and prepared figures and tables	analyzed the data, and prepared figures and tables	Analyzed the data	Formal analysis|Visualization	YES
5910442	29679179	JMZ	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5910442	29679179	QL	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5910442	29679179	RBS	2	analyzed the data, and prepared figures and tables	analyzed the data, and prepared figures and tables	Analyzed the data	Formal analysis|Visualization	YES
5910442	29679179	XHW	2	conceived and designed the study the study|performed experiments|analyzed the data, and prepared figures and tables|wrote the manuscript	conceived and designed the study the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5910442	29679179	XHW	2	conceived and designed the study the study|performed experiments|analyzed the data, and prepared figures and tables|wrote the manuscript	performed experiments	Performed the experiments	Investigation	YES
5910442	29679179	XHW	2	conceived and designed the study the study|performed experiments|analyzed the data, and prepared figures and tables|wrote the manuscript	analyzed the data, and prepared figures and tables	Analyzed the data	Formal analysis|Visualization	YES
5910442	29679179	XHW	2	conceived and designed the study the study|performed experiments|analyzed the data, and prepared figures and tables|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5910442	29679179	XLL	2	conceived and designed the study the study	conceived and designed the study the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5910442	29679179	XS	2	reviewed polished the paper	reviewed polished the paper	Wrote the paper	Writing - Review & Editing	YES
5910442	29679179	YRH	2	reviewed polished the paper	reviewed polished the paper	Wrote the paper	Writing - Review & Editing	YES
5910442	29679179	ZYLand	2	analyzed the data, and prepared figures and tables	analyzed the data, and prepared figures and tables	Analyzed the data	Formal analysis|Visualization	YES
6270822	24566321	Bogumil Brycki	2	contributed with valuable discussions and scientific input	contributed with valuable discussions and scientific input	-	-	NO
6270822	24566321	Hanna Koenig	2	was purifying compounds	was purifying compounds	Performed the experiments	Investigation	YES
6270822	24566321	Iwona Kowalczyk	2	contributed with valuable discussions and scientific input	contributed with valuable discussions and scientific input	-	-	NO
6270822	24566321	Tomasz Pospieszny	2	carried out of the synthetic work, interpretation of results and prepared the manuscript	carried out of the synthetic work, interpretation of results and prepared the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5789638	29378520	FCC	7	research plan development, data analysis, figures and manuscript preparation	research plan development, data analysis, figures and manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Visualization|Writing - Original Draft	YES
5789638	29378520	MR	7	principal advisor for research plan development, data analysis and manuscript preparation	principal advisor for research plan development, data analysis and manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5789638	29378520	SH	7	advisor on genomic analysis, data analysis and manuscript preparation	advisor on genomic analysis, data analysis and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4942911	27413534	AH	2	collected and assessed the data at each institution	collected and assessed the data at each institution	Performed the experiments	Investigation	YES
4942911	27413534	AK	2	collected and assessed the data at each institution	collected and assessed the data at each institution	Performed the experiments	Investigation	YES
4942911	27413534	AT	2	collected and assessed the data at each institution	collected and assessed the data at each institution	Performed the experiments	Investigation	YES
4942911	27413534	All authors	2	also read and approved the final manuscript	also read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4942911	27413534	HK	2	collected and assessed the data at each institution	collected and assessed the data at each institution	Performed the experiments	Investigation	YES
4942911	27413534	HM	2	designed the study and reviewed the data set|collected and assessed the data at each institution|interpreted the data and drafted the manuscript	designed the study and reviewed the data set	Conceived and designed the experiments	Methodology	YES
4942911	27413534	HM	2	designed the study and reviewed the data set|collected and assessed the data at each institution|interpreted the data and drafted the manuscript	collected and assessed the data at each institution	Performed the experiments	Investigation	YES
4942911	27413534	HM	2	designed the study and reviewed the data set|collected and assessed the data at each institution|interpreted the data and drafted the manuscript	interpreted the data and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4942911	27413534	HN	2	collected and assessed the data at each institution	collected and assessed the data at each institution	Performed the experiments	Investigation	YES
4942911	27413534	IF	2	collected and assessed the data at each institution	collected and assessed the data at each institution	Performed the experiments	Investigation	YES
4942911	27413534	IY	2	designed the study and reviewed the data set|collected and assessed the data at each institution|collected and assessed the data at each institution	designed the study and reviewed the data set	Conceived and designed the experiments	Methodology	YES
4942911	27413534	IY	2	designed the study and reviewed the data set|collected and assessed the data at each institution|collected and assessed the data at each institution	collected and assessed the data at each institution	Performed the experiments	Investigation	YES
4942911	27413534	IY	2	designed the study and reviewed the data set|collected and assessed the data at each institution|collected and assessed the data at each institution	collected and assessed the data at each institution	Performed the experiments	Investigation	YES
4942911	27413534	KD	2	designed the study and reviewed the data set|collected and assessed the data at each institution	designed the study and reviewed the data set	Conceived and designed the experiments	Methodology	YES
4942911	27413534	KD	2	designed the study and reviewed the data set|collected and assessed the data at each institution	collected and assessed the data at each institution	Performed the experiments	Investigation	YES
4942911	27413534	KH	2	collected and assessed the data at each institution	collected and assessed the data at each institution	Performed the experiments	Investigation	YES
4942911	27413534	KI	2	collected and assessed the data at each institution	collected and assessed the data at each institution	Performed the experiments	Investigation	YES
4942911	27413534	KT	2	collected and assessed the data at each institution	collected and assessed the data at each institution	Performed the experiments	Investigation	YES
4942911	27413534	KY	2	collected and assessed the data at each institution|collected and assessed the data at each institution	collected and assessed the data at each institution	Performed the experiments	Investigation	YES
4942911	27413534	KY	2	collected and assessed the data at each institution|collected and assessed the data at each institution	collected and assessed the data at each institution	Performed the experiments	Investigation	YES
4942911	27413534	MM	2	collected and assessed the data at each institution	collected and assessed the data at each institution	Performed the experiments	Investigation	YES
4942911	27413534	MT	2	designed the study and reviewed the data set|collected and assessed the data at each institution	designed the study and reviewed the data set	Conceived and designed the experiments	Methodology	YES
4942911	27413534	MT	2	designed the study and reviewed the data set|collected and assessed the data at each institution	collected and assessed the data at each institution	Performed the experiments	Investigation	YES
4942911	27413534	MW	2	collected and assessed the data at each institution	collected and assessed the data at each institution	Performed the experiments	Investigation	YES
4942911	27413534	NE	2	collected and assessed the data at each institution	collected and assessed the data at each institution	Performed the experiments	Investigation	YES
4942911	27413534	NS	2	collected and assessed the data at each institution	collected and assessed the data at each institution	Performed the experiments	Investigation	YES
4942911	27413534	NT	2	collected and assessed the data at each institution	collected and assessed the data at each institution	Performed the experiments	Investigation	YES
4942911	27413534	NY	2	collected and assessed the data at each institution	collected and assessed the data at each institution	Performed the experiments	Investigation	YES
4942911	27413534	OT	2	collected and assessed the data at each institution	collected and assessed the data at each institution	Performed the experiments	Investigation	YES
4942911	27413534	OY	2	collected and assessed the data at each institution	collected and assessed the data at each institution	Performed the experiments	Investigation	YES
4942911	27413534	SK	2	collected and assessed the data at each institution	collected and assessed the data at each institution	Performed the experiments	Investigation	YES
4942911	27413534	SM	2	designed the study and reviewed the data set|collected and assessed the data at each institution	designed the study and reviewed the data set	Conceived and designed the experiments	Methodology	YES
4942911	27413534	SM	2	designed the study and reviewed the data set|collected and assessed the data at each institution	collected and assessed the data at each institution	Performed the experiments	Investigation	YES
4942911	27413534	SN	2	collected and assessed the data at each institution	collected and assessed the data at each institution	Performed the experiments	Investigation	YES
4942911	27413534	SR	2	collected and assessed the data at each institution	collected and assessed the data at each institution	Performed the experiments	Investigation	YES
4942911	27413534	SS	2	designed the study and reviewed the data set|collected and assessed the data at each institution	designed the study and reviewed the data set	Conceived and designed the experiments	Methodology	YES
4942911	27413534	SS	2	designed the study and reviewed the data set|collected and assessed the data at each institution	collected and assessed the data at each institution	Performed the experiments	Investigation	YES
4942911	27413534	TA	2	collected and assessed the data at each institution	collected and assessed the data at each institution	Performed the experiments	Investigation	YES
4942911	27413534	TH	2	collected and assessed the data at each institution|collected and assessed the data at each institution	collected and assessed the data at each institution	Performed the experiments	Investigation	YES
4942911	27413534	TH	2	collected and assessed the data at each institution|collected and assessed the data at each institution	collected and assessed the data at each institution	Performed the experiments	Investigation	YES
4942911	27413534	TK	2	designed the study and reviewed the data set|collected and assessed the data at each institution	designed the study and reviewed the data set	Conceived and designed the experiments	Methodology	YES
4942911	27413534	TK	2	designed the study and reviewed the data set|collected and assessed the data at each institution	collected and assessed the data at each institution	Performed the experiments	Investigation	YES
4942911	27413534	TS	2	collected and assessed the data at each institution	collected and assessed the data at each institution	Performed the experiments	Investigation	YES
4942911	27413534	TT	2	collected and assessed the data at each institution	collected and assessed the data at each institution	Performed the experiments	Investigation	YES
4942911	27413534	UK	2	collected and assessed the data at each institution|collected and assessed the data at each institution	collected and assessed the data at each institution	Performed the experiments	Investigation	YES
4942911	27413534	UK	2	collected and assessed the data at each institution|collected and assessed the data at each institution	collected and assessed the data at each institution	Performed the experiments	Investigation	YES
4942911	27413534	US	2	designed the study and reviewed the data set	designed the study and reviewed the data set	Conceived and designed the experiments	Methodology	YES
4942911	27413534	WM	2	collected and assessed the data at each institution	collected and assessed the data at each institution	Performed the experiments	Investigation	YES
4942911	27413534	YK	2	designed the study and reviewed the data set	designed the study and reviewed the data set	Conceived and designed the experiments	Methodology	YES
4942911	27413534	YM	2	collected and assessed the data at each institution	collected and assessed the data at each institution	Performed the experiments	Investigation	YES
4942911	27413534	YS	2	collected and assessed the data at each institution	collected and assessed the data at each institution	Performed the experiments	Investigation	YES
4942911	27413534	YY	2	collected and assessed the data at each institution	collected and assessed the data at each institution	Performed the experiments	Investigation	YES
5394634	28396467	A.M.R.	2	conceived and designed the manuscript, drafted and revised the article, and approved the final version to be published	conceived and designed the manuscript, drafted and revised the article, and approved the final version to be published	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
5394634	28396467	P.W.H.	2	conceived and designed the manuscript, drafted and revised the article, and approved the final version to be published	conceived and designed the manuscript, drafted and revised the article, and approved the final version to be published	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
3569654	23143995	ALR	2	was involved in the immunostaining	was involved in the immunostaining	Performed the experiments	Investigation	YES
3569654	23143995	DHM	2	reviewed the manuscript and suggested additional key analyses|edited the manuscript	reviewed the manuscript and suggested additional key analyses	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
3569654	23143995	DHM	2	reviewed the manuscript and suggested additional key analyses|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
3569654	23143995	DRB	2	designed the study|edited the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
3569654	23143995	DRB	2	designed the study|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
3569654	23143995	JEA	2	obtained the patient blood samples	obtained the patient blood samples	Performed the experiments	Investigation	YES
3569654	23143995	JSH	2	designed the study|analyzed the data and performed most of the statistics	designed the study	Conceived and designed the experiments	Methodology	YES
3569654	23143995	JSH	2	designed the study|analyzed the data and performed most of the statistics	analyzed the data and performed most of the statistics	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3569654	23143995	KMT	2	obtained the patient blood samples	obtained the patient blood samples	Performed the experiments	Investigation	YES
3569654	23143995	SHA	2	designed the study|edited the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
3569654	23143995	SHA	2	designed the study|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
3569654	23143995	SW	2	isolated the rna and performed the qrt pcr	isolated the rna and performed the qrt pcr	Performed the experiments	Investigation	YES
3569654	23143995	SZP	2	provided the autopsy samples	provided the autopsy samples	Contributed reagents/materials/analysis tools	Resources	YES
3569654	23143995	WZ	2	designed the study|edited the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
3569654	23143995	WZ	2	designed the study|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
4418672	25938671	PvD	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418672	25938671	PvD	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418672	25938671	PvD	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418672	25938671	RAH	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418672	25938671	RAH	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418672	25938671	SvB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418672	25938671	SvB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418672	25938671	SvB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418672	25938671	YS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418672	25938671	YS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418672	25938671	YS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418672	25938671	YS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418672	25938671	YS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4647022	26613080	Jing Lu	2	contributed equally to this work	contributed equally to this work	-	-	NO
4647022	26613080	Zhong-Yuan Li	2	contributed equally to this work	contributed equally to this work	-	-	NO
1995753	17925871	AE	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1995753	17925871	CD	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1995753	17925871	CD	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1995753	17925871	FM	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1995753	17925871	MA	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1995753	17925871	RG	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1995753	17925871	RG	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1995753	17925871	RS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1995753	17925871	RS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1995753	17925871	SS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1995753	17925871	SS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1995753	17925871	TB	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1995753	17925871	TB	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5826276	29515609	CL	2	provided a vegetation inventory survey	provided a vegetation inventory survey	Performed the experiments	Investigation	YES
5826276	29515609	EM	2	lead the field work to recover the sediments	lead the field work to recover the sediments	Performed the experiments	Investigation	YES
5826276	29515609	HK	2	analysed the charcoal record and created the gis figure in figure	analysed the charcoal record and created the gis figure in figure	-	Visualization	YES
5826276	29515609	WG	2	lead the field work to recover the sediments	lead the field work to recover the sediments	Performed the experiments	Investigation	YES
5910447	29679312	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5910447	29679312	KHL	2	performed research|analyzed data and wrote the paper	performed research	Performed the experiments	Investigation	YES
5910447	29679312	KHL	2	performed research|analyzed data and wrote the paper	analyzed data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5910447	29679312	KPH	2	designed research|analyzed data and wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
5910447	29679312	KPH	2	designed research|analyzed data and wrote the paper	analyzed data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5910447	29679312	KYW	2	designed research	designed research	Conceived and designed the experiments	Methodology	YES
5910447	29679312	MST	2	performed research	performed research	Performed the experiments	Investigation	YES
5910447	29679312	MWT	2	analyzed data and wrote the paper	analyzed data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5910447	29679312	PYL	2	performed research	performed research	Performed the experiments	Investigation	YES
5910447	29679312	YCL	2	designed research|analyzed data and wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
5910447	29679312	YCL	2	designed research|analyzed data and wrote the paper	analyzed data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5910447	29679312	YKW	2	performed research	performed research	Performed the experiments	Investigation	YES
4947337	27429758	YK	2	drafted and approved the final manuscript	drafted and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5394635	28396468	All authors	2	contributed to the design, drafting and revision of the article and approved the final version for publication	contributed to the design, drafting and revision of the article and approved the final version for publication	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6270823	25415479	David Kitts	4	An equal contribution to the manuscript preparation was made by	An equal contribution to the manuscript preparation was made by	Wrote the paper	Writing - Original Draft	YES
6270823	25415479	Ningjian Liang	4	An equal contribution to the manuscript preparation was made by	An equal contribution to the manuscript preparation was made by	Wrote the paper	Writing - Original Draft	YES
5789663	29378510	AK	7	design, experimental work (RNA), functional analysis of rna seq data, data interpretation, writing and data report in form of the manuscript	design, experimental work (RNA), functional analysis of rna seq data, data interpretation, writing and data report in form of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5789663	29378510	LM	7	design, raw and functional analysis of rna seq data, data interpretation, writing and data report in form of the manuscript	design, raw and functional analysis of rna seq data, data interpretation, writing and data report in form of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5789663	29378510	LMi	7	experimental work (RNA, qpcr), data interpretation	experimental work (RNA, qpcr), data interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5789663	29378510	PT	7	experimental work (qpcr) and data interpretation	experimental work (qpcr) and data interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5789663	29378510	RM	7	experimental work (RNA), raw analysis of rna seq data, data interpretation, data report	experimental work (RNA), raw analysis of rna seq data, data interpretation, data report	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
1995754	17925872	AF	PLoS5	Communicated with treating physicians about clinical data	Communicated with treating physicians about clinical data	-	-	NO
1995754	17925872	AM	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1995754	17925872	HK	PLoS5	Conceived and designed the experiments|Wrote the paper|Supervised the project|Secured funds to support the study	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1995754	17925872	HK	PLoS5	Conceived and designed the experiments|Wrote the paper|Supervised the project|Secured funds to support the study	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1995754	17925872	HK	PLoS5	Conceived and designed the experiments|Wrote the paper|Supervised the project|Secured funds to support the study	Supervised the project	-	Supervision	YES
1995754	17925872	HK	PLoS5	Conceived and designed the experiments|Wrote the paper|Supervised the project|Secured funds to support the study	Secured funds to support the study	-	Funding acquisition	YES
1995754	17925872	LZ	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1995754	17925872	MB	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1995754	17925872	MB	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418673	25938585	AR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418673	25938585	AR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418673	25938585	AR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418673	25938585	AR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418673	25938585	DL	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4418673	25938585	DL	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418673	25938585	DS	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418673	25938585	DS	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418673	25938585	HH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418673	25938585	HH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418673	25938585	HH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418673	25938585	HH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418673	25938585	HH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418673	25938585	LL	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4418673	25938585	LL	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418673	25938585	LW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418673	25938585	LW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418673	25938585	LW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418673	25938585	WL	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper|Provided funding support and facilitated acquisition of lab space and equipment	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418673	25938585	WL	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper|Provided funding support and facilitated acquisition of lab space and equipment	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418673	25938585	WL	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper|Provided funding support and facilitated acquisition of lab space and equipment	Provided funding support and facilitated acquisition of lab space and equipment	Contributed reagents/materials/analysis tools	Funding acquisition|Resources	YES
5394636	28396469	A.M.J.	2	conceptualized the idea	conceptualized the idea	Conceived and designed the experiments	Conceptualization	YES
5394636	28396469	C.E.M.C.	2	conceptualized the idea	conceptualized the idea	Conceived and designed the experiments	Conceptualization	YES
3569655	23161797	AS	2	performed and designed some experiments, contributed to the manuscript	performed and designed some experiments, contributed to the manuscript	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3569655	23161797	BL	2	performed and designed some experiments, contributed to the manuscript	performed and designed some experiments, contributed to the manuscript	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3569655	23161797	BML	2	performed and designed some experiments, contributed to the manuscript	performed and designed some experiments, contributed to the manuscript	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3569655	23161797	CH	2	conceived, supervised and performed some experiments	conceived, supervised and performed some experiments	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Supervision	YES
3569655	23161797	DAR	2	conceived, supervised and performed some experiments	conceived, supervised and performed some experiments	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Supervision	YES
3569655	23161797	DCF	2	performed and designed some experiments, contributed to the manuscript	performed and designed some experiments, contributed to the manuscript	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3569655	23161797	DK	2	performed and designed some experiments, contributed to the manuscript	performed and designed some experiments, contributed to the manuscript	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3569655	23161797	DKV	2	conceived, supervised and performed some experiments	conceived, supervised and performed some experiments	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Supervision	YES
3569655	23161797	EAM	2	conceived, designed and conducted the majority of the experiments and wrote the manuscript	conceived, designed and conducted the majority of the experiments and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Writing - Original Draft	YES
3569655	23161797	EFH	2	performed and designed some experiments, contributed to the manuscript	performed and designed some experiments, contributed to the manuscript	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3569655	23161797	FL	2	conceived, supervised and performed some experiments	conceived, supervised and performed some experiments	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Supervision	YES
3569655	23161797	HB	2	conceived, supervised and performed some experiments	conceived, supervised and performed some experiments	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Supervision	YES
3569655	23161797	IHD	2	performed and designed some experiments, contributed to the manuscript	performed and designed some experiments, contributed to the manuscript	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3569655	23161797	JLS	2	performed and designed some experiments, contributed to the manuscript	performed and designed some experiments, contributed to the manuscript	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3569655	23161797	LAL	2	conceived, supervised and performed some experiments	conceived, supervised and performed some experiments	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Supervision	YES
3569655	23161797	MF	2	performed and designed some experiments, contributed to the manuscript	performed and designed some experiments, contributed to the manuscript	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3569655	23161797	MS	2	performed and designed some experiments, contributed to the manuscript	performed and designed some experiments, contributed to the manuscript	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3569655	23161797	RDC	2	performed some experiments, and conceived, supervised the scientific project and wrote the manuscript	performed some experiments, and conceived, supervised the scientific project and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Supervision|Writing - Original Draft	YES
3569655	23161797	RMa	2	performed and designed some experiments, contributed to the manuscript	performed and designed some experiments, contributed to the manuscript	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3569655	23161797	RMe	2	performed and designed some experiments, contributed to the manuscript	performed and designed some experiments, contributed to the manuscript	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3569655	23161797	SV	2	performed and designed some experiments, contributed to the manuscript	performed and designed some experiments, contributed to the manuscript	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3569655	23161797	TGM	2	conceived, supervised and performed some experiments	conceived, supervised and performed some experiments	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Supervision	YES
3569655	23161797	TNB	2	performed and designed some experiments, contributed to the manuscript	performed and designed some experiments, contributed to the manuscript	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4952054	27441091	BS	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4952054	27441091	DP	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
1995755	17925861	AP	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1995755	17925861	DK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1995755	17925861	MB	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1995755	17925861	MG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1995755	17925861	MR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1995755	17925861	MR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1995755	17925861	MR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1995755	17925861	PS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1995755	17925861	RT	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1995755	17925861	TS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1995755	17925861	TS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5826304	29515612	AM-Y	2	performed literature reviews and contributed to the discussion|wrote the manuscript	performed literature reviews and contributed to the discussion	Performed the experiments	Formal analysis|Investigation	YES
5826304	29515612	AM-Y	2	performed literature reviews and contributed to the discussion|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5826304	29515612	All authors	2	conceived and designed the manuscript	conceived and designed the manuscript	Conceived and designed the experiments	Conceptualization	YES
5826304	29515612	CB	2	performed literature reviews and contributed to the discussion	performed literature reviews and contributed to the discussion	Performed the experiments	Formal analysis|Investigation	YES
5826304	29515612	DP	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5826304	29515612	FAG	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5826304	29515612	JS	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5826304	29515612	MCR	2	performed literature reviews and contributed to the discussion	performed literature reviews and contributed to the discussion	Performed the experiments	Formal analysis|Investigation	YES
6270824	24995928	Aditya Arya	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
6270824	24995928	Behnam Kamalidehghan	PLoS5	Conceived and designed the study	Conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6270824	24995928	Hamed Karimian	PLoS5	Conceived and designed the study|Performed the experiments|Analysed the data|Wrote the manuscript	Conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6270824	24995928	Hamed Karimian	PLoS5	Conceived and designed the study|Performed the experiments|Analysed the data|Wrote the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
6270824	24995928	Hamed Karimian	PLoS5	Conceived and designed the study|Performed the experiments|Analysed the data|Wrote the manuscript	Analysed the data	Analyzed the data	Formal analysis	YES
6270824	24995928	Hamed Karimian	PLoS5	Conceived and designed the study|Performed the experiments|Analysed the data|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6270824	24995928	Hapipah Mohd Ali	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
6270824	24995928	Mahboubeh Razavi	PLoS5	Analysed the data	Analysed the data	Analyzed the data	Formal analysis	YES
6270824	24995928	Mehran Fadaeinasab	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
6270824	24995928	Mohamad Ibrahim Noordin	PLoS5	Conceived and designed the study	Conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6270824	24995928	Soheil Zorofchian Moghadamtousi	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
6270824	24995928	Syam Mohan	PLoS5	Conceived and designed the study	Conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5913057	29687201	AF	2	supplied materials and designed figures	supplied materials and designed figures	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Resources|Visualization	YES
5913057	29687201	AIHR	2	reviewed the literature and wrote the manuscript	reviewed the literature and wrote the manuscript	Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5913057	29687201	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5913057	29687201	Cao Yangchun	2	for his ideas, guidance, and kind co-supervision of this doctorate work	for his ideas, guidance, and kind co-supervision of this doctorate work	Conceived and designed the experiments	Conceptualization|Supervision	YES
5913057	29687201	JHY	2	conceived the idea, reviewed, and supervised the study	conceived the idea, reviewed, and supervised the study	Conceived and designed the experiments	Conceptualization|Supervision	YES
5913057	29687201	RH	2	supplied materials and designed figures	supplied materials and designed figures	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Resources|Visualization	YES
5913057	29687201	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5913057	29687201	YCC	2	conceived the idea, reviewed, and supervised the study	conceived the idea, reviewed, and supervised the study	Conceived and designed the experiments	Conceptualization|Supervision	YES
5789708	29378514	A.C.	2	performed the experiments and provided their expertise in the data analyses	performed the experiments and provided their expertise in the data analyses	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5789708	29378514	A.S.	2	analysed the phenotypic data	analysed the phenotypic data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5789708	29378514	All authors	2	edited and reviewed the final manuscript	edited and reviewed the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5789708	29378514	J.K.	2	contributed substantially to manuscript revision	contributed substantially to manuscript revision	Wrote the paper	Writing - Review & Editing	YES
5789708	29378514	J.P.	2	analysed the phenotypic data	analysed the phenotypic data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5789708	29378514	K.P.	2	analysed the sequence data and wrote the manuscript	analysed the sequence data and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4647025	26613084	All authors	PLoS52	contributed to literature search, planning the experiments, and writing the paper	contributed to literature search, planning the experiments, and writing the paper	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4647025	26613084	Giorgio La Fata	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
4647025	26613084	Nicole Seifert	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
1995756	17925873	QW	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1995756	17925873	QW	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1995756	17925873	QW	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1995756	17925873	YP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1995756	17925873	YP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1995756	17925873	YP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3569656	23197416	BHJC	2	contributed to discussions and reviewed the manuscript	contributed to discussions and reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
3569656	23197416	LC	2	designed and supervised experimental work, and revised the manuscript	designed and supervised experimental work, and revised the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Supervision|Writing - Review & Editing	YES
3569656	23197416	YY	2	designed and conducted the studies, and wrote the manuscript	designed and conducted the studies, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
4955156	27446590	KK	2	helped design the study, helped with data interpretation, and critically revised the manuscript	helped design the study, helped with data interpretation, and critically revised the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
4955156	27446590	MK	2	conceived the study, collected the data, performed the data analysis, and drafted manuscript	conceived the study, collected the data, performed the data analysis, and drafted manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
5791361	29382299	AP	PLoS52	participated in data and tissue sample collection	participated in data and tissue sample collection	Performed the experiments	Investigation	YES
5791361	29382299	NHN	PLoS52	conceived and designed the experiments|analysed the data and prepared the manuscript|participated in data and tissue sample collection	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5791361	29382299	NHN	PLoS52	conceived and designed the experiments|analysed the data and prepared the manuscript|participated in data and tissue sample collection	analysed the data and prepared the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5791361	29382299	NHN	PLoS52	conceived and designed the experiments|analysed the data and prepared the manuscript|participated in data and tissue sample collection	participated in data and tissue sample collection	Performed the experiments	Investigation	YES
5791361	29382299	WK	PLoS52	conceived and designed the experiments|overseen the study, managed the pedigree and the breeding program|participated in data and tissue sample collection	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5791361	29382299	WK	PLoS52	conceived and designed the experiments|overseen the study, managed the pedigree and the breeding program|participated in data and tissue sample collection	overseen the study, managed the pedigree and the breeding program	Performed the experiments	Investigation|Supervision	YES
5791361	29382299	WK	PLoS52	conceived and designed the experiments|overseen the study, managed the pedigree and the breeding program|participated in data and tissue sample collection	participated in data and tissue sample collection	Performed the experiments	Investigation	YES
4418674	25938239	APA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418674	25938239	APA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418674	25938239	APA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418674	25938239	CM	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418674	25938239	CM	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418674	25938239	FOS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418674	25938239	FOS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418674	25938239	FOS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418674	25938239	JDBJ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418674	25938239	MMA	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418674	25938239	MMA	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270825	25000465	Byeong Cheol Moon	2	collected plant materials and confirmed species	collected plant materials and confirmed species	Performed the experiments	Investigation	YES
6270825	25000465	Do Hyun Ryu	2	designed the study and wrote the manuscript	designed the study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
6270825	25000465	Geum-Sook Hwang	2	designed the study and wrote the manuscript	designed the study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
6270825	25000465	Ho Kyoung Kim	2	collected plant materials and confirmed species	collected plant materials and confirmed species	Performed the experiments	Investigation	YES
6270825	25000465	Jeoung-Hwa Shin	2	conducted the data generation and interpretation	conducted the data generation and interpretation	Analyzed the data	Formal analysis	YES
5826307	29515616	JH	7	reviewed and revised the manuscript	reviewed and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5826307	29515616	MJ	7	made the data analysis	made the data analysis	Analyzed the data	Formal analysis	YES
5826307	29515616	PP	7	analyzed the results and revised the manuscript	analyzed the results and revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5826307	29515616	YL	7	designed this study and developed the method	designed this study and developed the method	Conceived and designed the experiments|Performed the experiments	Methodology	YES
5918145	29696483	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5918145	29696483	CO	2	wrote the paper and performed research	wrote the paper and performed research	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5918145	29696483	DI	2	synthesized and provided the pentapeptides	synthesized and provided the pentapeptides	Performed the experiments	Investigation	YES
5918145	29696483	SO	2	wrote the paper and performed research|analyzed data	wrote the paper and performed research	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5918145	29696483	SO	2	wrote the paper and performed research|analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5918145	29696483	UK	2	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5394640	28396473	A.C.	PLoS52	devised the study	devised the study	Conceived and designed the experiments	Conceptualization	YES
5394640	28396473	A.J.K.	PLoS52	devised the study	devised the study	Conceived and designed the experiments	Conceptualization	YES
5394640	28396473	B.R.	PLoS52	devised the study|wrote a first draft of the paper	devised the study	Conceived and designed the experiments	Conceptualization	YES
5394640	28396473	B.R.	PLoS52	devised the study|wrote a first draft of the paper	wrote a first draft of the paper	Wrote the paper	Writing - Original Draft	YES
5394640	28396473	I.G.	PLoS52	devised the study	devised the study	Conceived and designed the experiments	Conceptualization	YES
5394640	28396473	S.F.	PLoS52	devised the study|analysed the data|wrote a first draft of the paper	devised the study	Conceived and designed the experiments	Conceptualization	YES
5394640	28396473	S.F.	PLoS52	devised the study|analysed the data|wrote a first draft of the paper	analysed the data	Analyzed the data	Formal analysis	YES
5394640	28396473	S.F.	PLoS52	devised the study|analysed the data|wrote a first draft of the paper	wrote a first draft of the paper	Wrote the paper	Writing - Original Draft	YES
5394640	28396473	W.J.E.	PLoS52	devised the study	devised the study	Conceived and designed the experiments	Conceptualization	YES
5394640	28396473	all authors	PLoS52	contributed to critical interpretation of the results and revision of the manuscript	contributed to critical interpretation of the results and revision of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
1995757	17925865	AA	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1995757	17925865	HN	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1995757	17925865	JR	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1995757	17925865	KH	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1995757	17925865	RE	PLoS5	Helped to conceptualize findings	Helped to conceptualize findings	Conceived and designed the experiments	Conceptualization	YES
1995757	17925865	RL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1995757	17925865	SL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1995757	17925865	SL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1995757	17925865	WL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1995757	17925865	WL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1995757	17925865	WL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1995757	17925865	WL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4647031	26613083	Apostolos Papalois	2	are equal contributors/authors, leaders of the project, designers of the course curriculum, and main editors of the manual	are equal contributors/authors, leaders of the project, designers of the course curriculum, and main editors of the manual	Conceived and designed the experiments	Methodology|Supervision	YES
4647031	26613083	Georgios Zografos	2	is a senior advisor of the course curriculum and manual and took the lead for the scientific committee of the course	is a senior advisor of the course curriculum and manual and took the lead for the scientific committee of the course	-	-	NO
4647031	26613083	Konstantinos Toutouzas	2	is a member of the faculty of the course and participated in the in vivo dissections	is a member of the faculty of the course and participated in the in vivo dissections	Performed the experiments	Investigation	YES
4647031	26613083	Michail Sideris	2	are equal contributors/authors, leaders of the project, designers of the course curriculum, and main editors of the manual	are equal contributors/authors, leaders of the project, designers of the course curriculum, and main editors of the manual	Conceived and designed the experiments	Methodology|Supervision	YES
4647031	26613083	Open Reduction Internal	2	ex vivo modules	ex vivo modules	-	-	NO
4647031	26613083	Savvas Papagrigoriadis	2	is a senior advisor of the course curriculum and manual and international lecturer during course	is a senior advisor of the course curriculum and manual and international lecturer during course	-	-	NO
4647031	26613083	Vassilios Papalois	2	is a senior advisor of the course curriculum and manual	is a senior advisor of the course curriculum and manual	-	-	NO
4418675	25938477	AH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418675	25938477	AH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418675	25938477	AH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418675	25938477	AH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418675	25938477	AH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418675	25938477	AJB	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4418675	25938477	AJB	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418675	25938477	ISR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418675	25938477	ISR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418675	25938477	ISR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418675	25938477	JJW	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4418675	25938477	JJW	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4418675	25938477	JJW	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418675	25938477	KSH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418675	25938477	KSH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4418675	25938477	KSH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4418675	25938477	KSH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418675	25938477	PW	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4418675	25938477	PW	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418675	25938477	RKG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418675	25938477	RKG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418675	25938477	RKG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5793348	29390965	AC	2	carried out bovine skeletal muscle cell isolation and culture, rna isolation, and microarray and qpcr analyses	carried out bovine skeletal muscle cell isolation and culture, rna isolation, and microarray and qpcr analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5793348	29390965	EB	2	carried out rna isolation and qpcr analyses	carried out rna isolation and qpcr analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5793348	29390965	JO	2	supervised the animal slaughter, and dissection	supervised the animal slaughter, and dissection	Performed the experiments	Investigation|Supervision	YES
5793348	29390965	TS	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
6270826	25389663	Chi-Ren Liao	2	performed the study and analyzed the data	performed the study and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270826	25389663	Chun-Pin Kao	2	wrote and revised the manuscript	wrote and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6270826	25389663	Kun-Chang Wu	2	performed the study and analyzed the data	performed the study and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270826	25389663	Yang Zhao	2	performed the study and analyzed the data|wrote and revised the manuscript	performed the study and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270826	25389663	Yang Zhao	2	performed the study and analyzed the data|wrote and revised the manuscript	wrote and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6270826	25389663	Yu-Ling Ho	2	designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
6270826	25389663	Yuan-Shiun Chang	2	designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
6270826	25389663	all authors	2	read and approved the final version	read and approved the final version	-	-	NO
4957921	27453785	CY	2	assisted with the experiments	assisted with the experiments	Performed the experiments	Investigation	YES
4957921	27453785	HN	2	assisted with the experiments	assisted with the experiments	Performed the experiments	Investigation	YES
4957921	27453785	MK	2	participated in the study design and manuscript writing	participated in the study design and manuscript writing	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4957921	27453785	MS	2	performed the research	performed the research	Performed the experiments	Investigation	YES
4957921	27453785	NK	2	performed the research	performed the research	Performed the experiments	Investigation	YES
4957921	27453785	ON	2	participated in the study design and manuscript writing	participated in the study design and manuscript writing	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4957921	27453785	TN	2	performed the research	performed the research	Performed the experiments	Investigation	YES
4957921	27453785	TS	2	performed the research	performed the research	Performed the experiments	Investigation	YES
4957921	27453785	YH	2	performed the research	performed the research	Performed the experiments	Investigation	YES
4957921	27453785	YK	2	performed the research	performed the research	Performed the experiments	Investigation	YES
4957921	27453785	YS	2	designed, performed all of the experiments, and wrote the manuscript	designed, performed all of the experiments, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
1995758	17925858	BT	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1995758	17925858	BT	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1995758	17925858	MM	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1995758	17925858	MM	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1995758	17925858	MT	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
1995758	17925858	MT	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1995758	17925858	TP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1995758	17925858	TP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1995758	17925858	TP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1995758	17925858	TY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1995758	17925858	TY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1995758	17925858	TY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1995758	17925858	TY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5826315	29515600	RS	2	conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5826315	29515600	XG	2	conceived the study|undertook experiments and analyzed the data	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5826315	29515600	XG	2	conceived the study|undertook experiments and analyzed the data	undertook experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5826315	29515600	all authors	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4418676	25938778	FY	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418676	25938778	GLL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418676	25938778	HF	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418676	25938778	JG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418676	25938778	JH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418676	25938778	JHD	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418676	25938778	JL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418676	25938778	JPL	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418676	25938778	LPS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418676	25938778	MHY	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418676	25938778	PL	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418676	25938778	WYY	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418676	25938778	XPJ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418676	25938778	YL	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418676	25938778	YMW	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418676	25938778	YPC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418676	25938778	YYD	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5918149	29696463	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5918149	29696463	CW	2	was the first author of this work	was the first author of this work	-	-	NO
5918149	29696463	HW	2	modified the manuscript text|is the corresponding author	modified the manuscript text	Wrote the paper	Writing - Review & Editing	YES
5918149	29696463	HW	2	modified the manuscript text|is the corresponding author	is the corresponding author	-	-	NO
5918149	29696463	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5918149	29696463	YH	2	helped to improve the research ideas and analyze the gene related data in this study	helped to improve the research ideas and analyze the gene related data in this study	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
5918149	29696463	ZZ	2	provided the method for intermediates detection	provided the method for intermediates detection	Performed the experiments	Investigation	YES
6432617	30996961	A.S.B.	2	performed hab phenotypic screening	performed hab phenotypic screening	Performed the experiments	Investigation	YES
6432617	30996961	E.C.-G.	2	designed, performed and analysed the hab -zebrafish experiments and contributed to the writing of the manuscript	designed, performed and analysed the hab -zebrafish experiments and contributed to the writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
6432617	30996961	I.C.B.	2	performed the fluorescence spectroscopy experiments	performed the fluorescence spectroscopy experiments	Performed the experiments	Investigation	YES
6432617	30996961	K.L.	2	performed the hrms analysis	performed the hrms analysis	Performed the experiments	Investigation	YES
6432617	30996961	M.B.	2	performed the fluorescence spectroscopy experiments	performed the fluorescence spectroscopy experiments	Performed the experiments	Investigation	YES
6432617	30996961	P.H.	2	assisted with helpful discussion and participated in the writing of the manuscript	assisted with helpful discussion and participated in the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
6432617	30996961	PBMC	2	performed the hrms analysis	performed the hrms analysis	Performed the experiments	Investigation	YES
6432617	30996961	S.D.S.O.	2	performed hab phenotypic screening	performed hab phenotypic screening	Performed the experiments	Investigation	YES
3569657	23180565	AM	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
3569657	23180565	CES	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
3569657	23180565	JO	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
3569657	23180565	KEW	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
3569657	23180565	RJT	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
3569657	23180565	SAS	2	designed and performed experiments, analysed and interpreted data, performed statistical analysis, made the figures, and wrote the manuscript	designed and performed experiments, analysed and interpreted data, performed statistical analysis, made the figures, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Visualization|Writing - Original Draft	YES
3569657	23180565	SG	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
3569657	23180565	SPS	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
3569657	23180565	YKP	2	performed the structural analysis and docking simulations	performed the structural analysis and docking simulations	Performed the experiments	Formal analysis|Investigation	YES
3569657	23180565	ZMS	2	designed and synthesized ceramide and fty720 analogues	designed and synthesized ceramide and fty720 analogues	Conceived and designed the experiments|Performed the experiments	Investigation	YES
4418687	25938432	FS	PLoS5	Analyzed the data|Wrote the paper|Conceived and designed the methodology	Analyzed the data	Analyzed the data	Formal analysis	YES
4418687	25938432	FS	PLoS5	Analyzed the data|Wrote the paper|Conceived and designed the methodology	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418687	25938432	FS	PLoS5	Analyzed the data|Wrote the paper|Conceived and designed the methodology	Conceived and designed the methodology	Conceived and designed the experiments|Performed the experiments	Conceptualization|Methodology	YES
4418687	25938432	JM	PLoS5	Analyzed the data|Wrote the paper|Conceived and designed the methodology	Analyzed the data	Analyzed the data	Formal analysis	YES
4418687	25938432	JM	PLoS5	Analyzed the data|Wrote the paper|Conceived and designed the methodology	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418687	25938432	JM	PLoS5	Analyzed the data|Wrote the paper|Conceived and designed the methodology	Conceived and designed the methodology	Conceived and designed the experiments|Performed the experiments	Conceptualization|Methodology	YES
4418687	25938432	SS	PLoS5	Analyzed the data|Wrote the paper|Designed software	Analyzed the data	Analyzed the data	Formal analysis	YES
4418687	25938432	SS	PLoS5	Analyzed the data|Wrote the paper|Designed software	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418687	25938432	SS	PLoS5	Analyzed the data|Wrote the paper|Designed software	Designed software	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
4966815	27478617	HY	2	critically reviewed and revised the manuscript	critically reviewed and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4966815	27478617	KO	2	critically reviewed and revised the manuscript	critically reviewed and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4966815	27478617	NS	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4966815	27478617	ST	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5394646	28396479	A.C.	2	contributed to the analyses and drafting of the manuscript	contributed to the analyses and drafting of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5394646	28396479	All authors	2	contributed to data curation, analysis and interpretation and critically revised and approved the manuscript	contributed to data curation, analysis and interpretation and critically revised and approved the manuscript	Analyzed the data|Wrote the paper	Data curation|Formal analysis|Writing - Review & Editing	YES
5394646	28396479	C.A.D.	2	conceived the analysis	conceived the analysis	Conceived and designed the experiments	Conceptualization	YES
5394646	28396479	T.G.	2	performed the analyses and drafted the manuscript|conceived the analysis	performed the analyses and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5394646	28396479	T.G.	2	performed the analyses and drafted the manuscript|conceived the analysis	conceived the analysis	Conceived and designed the experiments	Conceptualization	YES
1995759	17925857	HH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1995759	17925857	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1995759	17925857	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1995759	17925857	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1995759	17925857	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1995759	17925857	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1995759	17925857	SL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1995759	17925857	SL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1995759	17925857	SL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1995759	17925857	SL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5826348	29515601	BC	2	conducted some physiological assays	conducted some physiological assays	Performed the experiments	Investigation	YES
5826348	29515601	H-JS	2	measured the aba levels	measured the aba levels	Performed the experiments	Investigation	YES
5826348	29515601	HK	2	measured the aba levels	measured the aba levels	Performed the experiments	Investigation	YES
5826348	29515601	IH	2	devised and supervised the project and wrote the manuscript|revised and approved the manuscript	devised and supervised the project and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Supervision|Writing - Original Draft	YES
5826348	29515601	IH	2	devised and supervised the project and wrote the manuscript|revised and approved the manuscript	revised and approved the manuscript	Wrote the paper	Writing - Review & Editing	YES
5826348	29515601	JL	2	designed the experiments, analyzed the data, and performed the most experiments|performed the most experiments|revised and approved the manuscript	designed the experiments, analyzed the data, and performed the most experiments	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5826348	29515601	JL	2	designed the experiments, analyzed the data, and performed the most experiments|performed the most experiments|revised and approved the manuscript	performed the most experiments	Performed the experiments	Investigation	YES
5826348	29515601	JL	2	designed the experiments, analyzed the data, and performed the most experiments|performed the most experiments|revised and approved the manuscript	revised and approved the manuscript	Wrote the paper	Writing - Review & Editing	YES
5826348	29515601	MW	2	designed the experiments, analyzed the data, and performed the most experiments|performed the most experiments|revised and approved the manuscript	designed the experiments, analyzed the data, and performed the most experiments	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5826348	29515601	MW	2	designed the experiments, analyzed the data, and performed the most experiments|performed the most experiments|revised and approved the manuscript	performed the most experiments	Performed the experiments	Investigation	YES
5826348	29515601	MW	2	designed the experiments, analyzed the data, and performed the most experiments|performed the most experiments|revised and approved the manuscript	revised and approved the manuscript	Wrote the paper	Writing - Review & Editing	YES
5826348	29515601	YP	2	conducted some physiological assays	conducted some physiological assays	Performed the experiments	Investigation	YES
5924506	29704067	All	2	the methods were carried out in accordance with relevant guidelines and regulations, including any relevant details	the methods were carried out in accordance with relevant guidelines and regulations, including any relevant details	Performed the experiments	Investigation	YES
5924506	29704067	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5924506	29704067	DZ	2	conceived of the study, collected the experimental material, and participated in the writing of the zoology section	conceived of the study, collected the experimental material, and participated in the writing of the zoology section	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
5924506	29704067	HZ	2	designed the experimental program, participated in the examination and drafted the manuscript	designed the experimental program, participated in the examination and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5924506	29704067	LLN	2	collected and analyzed the raw data	collected and analyzed the raw data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5924506	29704067	NW	2	participated in drafting the manuscript	participated in drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
5924506	29704067	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5924506	29704067	YZ	2	participated in the qpcr	participated in the qpcr	Performed the experiments	Investigation	YES
4418688	25938487	LH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418688	25938487	LH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418688	25938487	LH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418688	25938487	MZ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418688	25938487	MZ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418688	25938487	MZ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418688	25938487	PS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418688	25938487	PS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418688	25938487	PS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418688	25938487	WG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418688	25938487	WG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418688	25938487	WG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418688	25938487	WG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418688	25938487	WG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418688	25938487	XC	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418688	25938487	XC	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418688	25938487	XC	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418688	25938487	XC	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418688	25938487	XW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418688	25938487	XW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418688	25938487	XW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418688	25938487	YL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418688	25938487	YL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418688	25938487	YL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418688	25938487	YT	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418688	25938487	YT	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418688	25938487	YT	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418688	25938487	YZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418688	25938487	YZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418688	25938487	YZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418688	25938487	YZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4649073	26618168	Antonio Lleo-Perez	2	collaborated equally in the present work, sharing the first place	collaborated equally in the present work, sharing the first place	Performed the experiments	Investigation	YES
4649073	26618168	Barbara Vivar-Llopis	2	collaborated equally in the present work, sharing the first place	collaborated equally in the present work, sharing the first place	Performed the experiments	Investigation	YES
4649073	26618168	Maria J. Roig-Revert	2	collaborated equally in the present work, sharing the first place	collaborated equally in the present work, sharing the first place	Performed the experiments	Investigation	YES
4649073	26618168	Vicente Zanon-Moreno	2	collaborated equally in the present work, sharing the first place	collaborated equally in the present work, sharing the first place	Performed the experiments	Investigation	YES
4982209	27525106	CH	2	conceived the study and participated in its design and coordination and helped to draft the manuscript	conceived the study and participated in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
4982209	27525106	CM	2	participated in the design of the study	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
4982209	27525106	DY	2	participated in the design of the study	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
4982209	27525106	JD	2	participated in the design of the study	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
4982209	27525106	JM	2	performed the economic and statistical analyses and drafted the manuscript	performed the economic and statistical analyses and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4982209	27525106	PH	2	participated in the economic and statistical analyses	participated in the economic and statistical analyses	Analyzed the data	Formal analysis	YES
4982209	27525106	PHa	2	participated in the economic and statistical analyses	participated in the economic and statistical analyses	Analyzed the data	Formal analysis	YES
4982209	27525106	RL	2	participated in the economic and statistical analyses	participated in the economic and statistical analyses	Analyzed the data	Formal analysis	YES
4982209	27525106	SL	2	participated in the design of the study	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
3569658	23180554	AV	2	designed research, interpreted data and participated in manuscript writing	designed research, interpreted data and participated in manuscript writing	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3569658	23180554	CMN	2	contributed reagents and scientific input	contributed reagents and scientific input	Contributed reagents/materials/analysis tools	Resources	YES
3569658	23180554	DB	2	designed and performed most experiments and statistical analysis	designed and performed most experiments and statistical analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
3569658	23180554	ME	2	designed and performed experiments and statistical analysis and wrote the manuscript	designed and performed experiments and statistical analysis and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
3569658	23180554	MK	2	collected cord blood	collected cord blood	Performed the experiments	Investigation	YES
3569658	23180554	SS	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
6270828	25342553	A. Al-Dhabi	PLoS52	planned the experiments	planned the experiments	Conceived and designed the experiments	Conceptualization	YES
6270828	25342553	H. Cho	PLoS52	conducted experiments	conducted experiments	Performed the experiments	Investigation	YES
6270828	25342553	U. Park	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270828	25342553	V. Arasu	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
6270828	25342553	Xiaohua Li	PLoS52	conducted experiments	conducted experiments	Performed the experiments	Investigation	YES
1995760	17925859	JG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1995760	17925859	JG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1995760	17925859	JG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1995760	17925859	TG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1995760	17925859	TG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1995760	17925859	TG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5394647	28396480	A.C.	2	conceived and designed the study, and wrote the first draft of the paper	conceived and designed the study, and wrote the first draft of the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
5394647	28396480	All authors	2	contributed to revisions and gave their final approval for publication	contributed to revisions and gave their final approval for publication	Wrote the paper	Writing - Review & Editing	YES
5394647	28396480	H.L.M.	2	conceived and designed the study, and wrote the first draft of the paper	conceived and designed the study, and wrote the first draft of the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
5394647	28396480	I.M.B.	2	conceived and designed the study, and wrote the first draft of the paper	conceived and designed the study, and wrote the first draft of the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
5826354	29515615	DNA	2	prepared pools	prepared pools	-	-	NO
3569659	23197407	All authors	2	participated in discussing the work	participated in discussing the work	-	-	NO
3569659	23197407	CC	2	provided instructive suggestions	provided instructive suggestions	-	Supervision	YES
3569659	23197407	JH	2	provided instructive suggestions	provided instructive suggestions	-	Supervision	YES
3569659	23197407	ZGS	2	provided the human samples	provided the human samples	Contributed reagents/materials/analysis tools	Resources	YES
5796560	29390960	EK	2	designed the te targeting protocol|designed the te detection algorithm|conducted the experiments, designed and wrote the code implementing the algorithm|analyzed, interpreted the results, and wrote the manuscript|wrote, reviewed, and edited the manuscript	designed the te targeting protocol	Conceived and designed the experiments	Methodology	YES
5796560	29390960	EK	2	designed the te targeting protocol|designed the te detection algorithm|conducted the experiments, designed and wrote the code implementing the algorithm|analyzed, interpreted the results, and wrote the manuscript|wrote, reviewed, and edited the manuscript	designed the te detection algorithm	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5796560	29390960	EK	2	designed the te targeting protocol|designed the te detection algorithm|conducted the experiments, designed and wrote the code implementing the algorithm|analyzed, interpreted the results, and wrote the manuscript|wrote, reviewed, and edited the manuscript	conducted the experiments, designed and wrote the code implementing the algorithm	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Methodology|Software|Writing - Original Draft	YES
5796560	29390960	EK	2	designed the te targeting protocol|designed the te detection algorithm|conducted the experiments, designed and wrote the code implementing the algorithm|analyzed, interpreted the results, and wrote the manuscript|wrote, reviewed, and edited the manuscript	analyzed, interpreted the results, and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5796560	29390960	EK	2	designed the te targeting protocol|designed the te detection algorithm|conducted the experiments, designed and wrote the code implementing the algorithm|analyzed, interpreted the results, and wrote the manuscript|wrote, reviewed, and edited the manuscript	wrote, reviewed, and edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5796560	29390960	GL	2	designed the te targeting protocol|designed the te detection algorithm|analyzed, interpreted the results, and wrote the manuscript|wrote, reviewed, and edited the manuscript	designed the te targeting protocol	Conceived and designed the experiments	Methodology	YES
5796560	29390960	GL	2	designed the te targeting protocol|designed the te detection algorithm|analyzed, interpreted the results, and wrote the manuscript|wrote, reviewed, and edited the manuscript	designed the te detection algorithm	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5796560	29390960	GL	2	designed the te targeting protocol|designed the te detection algorithm|analyzed, interpreted the results, and wrote the manuscript|wrote, reviewed, and edited the manuscript	analyzed, interpreted the results, and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5796560	29390960	GL	2	designed the te targeting protocol|designed the te detection algorithm|analyzed, interpreted the results, and wrote the manuscript|wrote, reviewed, and edited the manuscript	wrote, reviewed, and edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5796560	29390960	JCT	2	provided samples|wrote, reviewed, and edited the manuscript	provided samples	Contributed reagents/materials/analysis tools	Resources	YES
5796560	29390960	JCT	2	provided samples|wrote, reviewed, and edited the manuscript	wrote, reviewed, and edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5796560	29390960	PP	2	designed the te targeting protocol|wrote, reviewed, and edited the manuscript	designed the te targeting protocol	Conceived and designed the experiments	Methodology	YES
5796560	29390960	PP	2	designed the te targeting protocol|wrote, reviewed, and edited the manuscript	wrote, reviewed, and edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4983782	27529031	CCF	2	helped to draft the manuscript and prepared the images and video clips	helped to draft the manuscript and prepared the images and video clips	Analyzed the data|Wrote the paper	Visualization|Writing - Original Draft	YES
4983782	27529031	CKC	2	conceived the study and participated in its design and coordination and helped to draft the manuscript	conceived the study and participated in its design and coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
4983782	27529031	LCM	2	conceived the study, helped to organize the study, and edited the final manuscript	conceived the study, helped to organize the study, and edited the final manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Project administration|Writing - Review & Editing	YES
4983782	27529031	WTL	2	conceived the study and helped to organize the study	conceived the study and helped to organize the study	Conceived and designed the experiments	Conceptualization|Project administration	YES
5928015	29713833	CZB	PLoS5	Conceived and designed the experiment	Conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5928015	29713833	HTS	PLoS5	Data analysis	Data analysis	Analyzed the data	Formal analysis	YES
5928015	29713833	HXQ	PLoS5	Conceived and designed the experiment|Wrote the paper	Conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5928015	29713833	HXQ	PLoS5	Conceived and designed the experiment|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5928015	29713833	LHZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5928015	29713833	YZS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418689	25938594	CL	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4418689	25938594	CL	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418689	25938594	DMM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418689	25938594	DMM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418689	25938594	DMM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418689	25938594	GHC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418689	25938594	GHC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418689	25938594	GHC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418689	25938594	SN	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4418689	25938594	SN	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418689	25938594	WWR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418689	25938594	WWR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418689	25938594	WWR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418689	25938594	WWR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418689	25938594	XX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418689	25938594	XX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4418689	25938594	XX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
6270829	24691064	All the authors	PLoS52	analyzed the data and discussed the results	analyzed the data and discussed the results	Analyzed the data	Formal analysis	YES
6270829	24691064	F. Huang	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
6270829	24691064	F. Zhang	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
6270829	24691064	W. Zhang	PLoS52	conceived of this study and designed the experiments	conceived of this study and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6270829	24691064	Y. Yang	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
1995761	17925860	FP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1995761	17925860	FP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1995761	17925860	FP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1995761	17925860	HN	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1995761	17925860	HR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1995761	17925860	HR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1995761	17925860	HR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1995761	17925860	HR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1995761	17925860	HR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1995761	17925860	ME	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1995761	17925860	OE	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1995761	17925860	PT	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1995761	17925860	PT	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1995761	17925860	SN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1995761	17925860	SN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1995761	17925860	SN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1995761	17925860	SN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1995761	17925860	SN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1995761	17925860	SR	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1995761	17925860	SR	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1995761	17925860	SZ	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
1995761	17925860	SZ	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5413868	28438909	All authors	2	contributed substantially to writing and provided final approval of published version	contributed substantially to writing and provided final approval of published version	Wrote the paper	-	YES
5413868	28438909	B.A.	2	all contributed to design and conception of critical components of the project	all contributed to design and conception of critical components of the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5413868	28438909	C.L.N.	2	all contributed to design and conception of critical components of the project|all contributed to acquisition, analysis and interpretation of data	all contributed to design and conception of critical components of the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5413868	28438909	C.L.N.	2	all contributed to design and conception of critical components of the project|all contributed to acquisition, analysis and interpretation of data	all contributed to acquisition, analysis and interpretation of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5413868	28438909	D.J.M.	2	all contributed to design and conception of critical components of the project|all contributed to acquisition, analysis and interpretation of data	all contributed to design and conception of critical components of the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5413868	28438909	D.J.M.	2	all contributed to design and conception of critical components of the project|all contributed to acquisition, analysis and interpretation of data	all contributed to acquisition, analysis and interpretation of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5413868	28438909	D.J.S.	2	all contributed to design and conception of critical components of the project|all contributed to acquisition, analysis and interpretation of data	all contributed to design and conception of critical components of the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5413868	28438909	D.J.S.	2	all contributed to design and conception of critical components of the project|all contributed to acquisition, analysis and interpretation of data	all contributed to acquisition, analysis and interpretation of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5413868	28438909	E.F.L.	2	all contributed to design and conception of critical components of the project	all contributed to design and conception of critical components of the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5413868	28438909	E.R.C.	2	all contributed to acquisition, analysis and interpretation of data	all contributed to acquisition, analysis and interpretation of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5413868	28438909	E.R.O.	2	all contributed to acquisition, analysis and interpretation of data	all contributed to acquisition, analysis and interpretation of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5413868	28438909	H.S.Y.	2	all contributed to design and conception of critical components of the project|all contributed to acquisition, analysis and interpretation of data	all contributed to design and conception of critical components of the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5413868	28438909	H.S.Y.	2	all contributed to design and conception of critical components of the project|all contributed to acquisition, analysis and interpretation of data	all contributed to acquisition, analysis and interpretation of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5413868	28438909	K.E.V.	2	all contributed to design and conception of critical components of the project	all contributed to design and conception of critical components of the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5413868	28438909	K.M.H.	2	all contributed to design and conception of critical components of the project|all contributed to acquisition, analysis and interpretation of data	all contributed to design and conception of critical components of the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5413868	28438909	K.M.H.	2	all contributed to design and conception of critical components of the project|all contributed to acquisition, analysis and interpretation of data	all contributed to acquisition, analysis and interpretation of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5413868	28438909	K.S.	2	all contributed to acquisition, analysis and interpretation of data	all contributed to acquisition, analysis and interpretation of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5413868	28438909	M.G.C.	2	all contributed to acquisition, analysis and interpretation of data	all contributed to acquisition, analysis and interpretation of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5413868	28438909	R.D.	2	all contributed to design and conception of critical components of the project|all contributed to acquisition, analysis and interpretation of data	all contributed to design and conception of critical components of the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5413868	28438909	R.D.	2	all contributed to design and conception of critical components of the project|all contributed to acquisition, analysis and interpretation of data	all contributed to acquisition, analysis and interpretation of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5413868	28438909	R.F.	2	all contributed to acquisition, analysis and interpretation of data	all contributed to acquisition, analysis and interpretation of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5413868	28438909	R.M.P.	2	all contributed to design and conception of critical components of the project	all contributed to design and conception of critical components of the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5413868	28438909	T.M.P.	2	all contributed to design and conception of critical components of the project	all contributed to design and conception of critical components of the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
3569660	23180582	AEV	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
3569660	23180582	AR	PLoS52	wrote a grant that funded the clinical part of the work|wrote the manuscript	wrote a grant that funded the clinical part of the work	Performed the experiments|Wrote the paper	Funding acquisition|Investigation|Writing - Original Draft	YES
3569660	23180582	AR	PLoS52	wrote a grant that funded the clinical part of the work|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3569660	23180582	JAE	PLoS52	assisted with the editing of the manuscript	assisted with the editing of the manuscript	Wrote the paper	Writing - Review & Editing	YES
3569660	23180582	JAS	PLoS52	wrote a grant that funded the clinical part of the work|assisted with the editing of the manuscript	wrote a grant that funded the clinical part of the work	Performed the experiments|Wrote the paper	Funding acquisition|Investigation|Writing - Original Draft	YES
3569660	23180582	JAS	PLoS52	wrote a grant that funded the clinical part of the work|assisted with the editing of the manuscript	assisted with the editing of the manuscript	Wrote the paper	Writing - Review & Editing	YES
3569660	23180582	KIA	PLoS52	wrote a grant that funded the clinical part of the work	wrote a grant that funded the clinical part of the work	Performed the experiments|Wrote the paper	Funding acquisition|Investigation|Writing - Original Draft	YES
3569660	23180582	MCK	PLoS52	wrote a grant that funded the clinical part of the work|collected the clinical samples|assisted with the editing of the manuscript	wrote a grant that funded the clinical part of the work	Performed the experiments|Wrote the paper	Funding acquisition|Investigation|Writing - Original Draft	YES
3569660	23180582	MCK	PLoS52	wrote a grant that funded the clinical part of the work|collected the clinical samples|assisted with the editing of the manuscript	collected the clinical samples	Performed the experiments	Investigation	YES
3569660	23180582	MCK	PLoS52	wrote a grant that funded the clinical part of the work|collected the clinical samples|assisted with the editing of the manuscript	assisted with the editing of the manuscript	Wrote the paper	Writing - Review & Editing	YES
3569660	23180582	OEH	PLoS52	performed the experiments|assisted with the editing of the manuscript	performed the experiments	Performed the experiments	Investigation	YES
3569660	23180582	OEH	PLoS52	performed the experiments|assisted with the editing of the manuscript	assisted with the editing of the manuscript	Wrote the paper	Writing - Review & Editing	YES
3569660	23180582	RCS	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
3569660	23180582	SS	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
3569660	23180582	TS	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
3569660	23180582	YL	PLoS52	performed the experiments|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
3569660	23180582	YL	PLoS52	performed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3569660	23180582	YMT	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
3569660	23180582	YS	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5826379	29515613	All authors	2	contributed to the writing of the manuscript and approved submission	contributed to the writing of the manuscript and approved submission	Wrote the paper	Writing - Original Draft	YES
5826379	29515613	BV	2	the chemical analysis of the plant, water, and growing media	the chemical analysis of the plant, water, and growing media	Performed the experiments	Investigation	YES
5826379	29515613	PC	2	the chemical analysis of the plant, water, and growing media	the chemical analysis of the plant, water, and growing media	Performed the experiments	Investigation	YES
5826379	29515613	TDS	2	the plant development analysis	the plant development analysis	Performed the experiments	Investigation	YES
5797364	29394889	All authors	PLoS52	reviewed and considered the manuscript	reviewed and considered the manuscript	Wrote the paper	Writing - Review & Editing	YES
5797364	29394889	XBT	PLoS52	performed the experiments|wrote the manuscript|provided technical and material support	performed the experiments	Performed the experiments	Investigation	YES
5797364	29394889	XBT	PLoS52	performed the experiments|wrote the manuscript|provided technical and material support	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5797364	29394889	XBT	PLoS52	performed the experiments|wrote the manuscript|provided technical and material support	provided technical and material support	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5797364	29394889	ZHZ	PLoS52	designed the experiments|wrote the manuscript|provided technical and material support	designed the experiments	Conceived and designed the experiments	Methodology	YES
5797364	29394889	ZHZ	PLoS52	designed the experiments|wrote the manuscript|provided technical and material support	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5797364	29394889	ZHZ	PLoS52	designed the experiments|wrote the manuscript|provided technical and material support	provided technical and material support	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5797364	29394889	ZKL	PLoS52	provided technical and material support	provided technical and material support	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
4983789	27529030	Both authors	2	contributed to the figures, read, and approved the final manuscript	contributed to the figures, read, and approved the final manuscript	Wrote the paper	Visualization|Writing - Review & Editing	YES
4983789	27529030	HCT	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4983789	27529030	YRH	2	conceived the review, performed the literature search, and wrote the first draft of this paper	conceived the review, performed the literature search, and wrote the first draft of this paper	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
4649083	26618171	Guanglu Jiang	2	carried out the drug susceptibility test	carried out the drug susceptibility test	Performed the experiments	Investigation	YES
4649083	26618171	Hairong Huang	2	were responsible for data analysis|was responsible for the conception of the study design and preparation of the paper	were responsible for data analysis	Analyzed the data	Formal analysis	YES
4649083	26618171	Hairong Huang	2	were responsible for data analysis|was responsible for the conception of the study design and preparation of the paper	was responsible for the conception of the study design and preparation of the paper	Conceived and designed the experiments	Conceptualization|Methodology	YES
4649083	26618171	Liping Zhao	2	carried out the experimental data and analysis and drafted the paper	carried out the experimental data and analysis and drafted the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4649083	26618171	Weimin Li	2	were responsible for data analysis	were responsible for data analysis	Analyzed the data	Formal analysis	YES
4649083	26618171	Xia Yu	2	carried out the experimental data and analysis and drafted the paper	carried out the experimental data and analysis and drafted the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4649083	26618171	Yifeng Ma	2	carried out the drug susceptibility test	carried out the drug susceptibility test	Performed the experiments	Investigation	YES
6270830	24950436	J.S.S.	1	Participated in research design|Conducted experiments|Performed data analysis|Wrote or contributed to the writing of the manuscript	Participated in research design	Conceived and designed the experiments	-	YES
6270830	24950436	J.S.S.	1	Participated in research design|Conducted experiments|Performed data analysis|Wrote or contributed to the writing of the manuscript	Conducted experiments	Performed the experiments	Investigation	YES
6270830	24950436	J.S.S.	1	Participated in research design|Conducted experiments|Performed data analysis|Wrote or contributed to the writing of the manuscript	Performed data analysis	Analyzed the data	Formal analysis	YES
6270830	24950436	J.S.S.	1	Participated in research design|Conducted experiments|Performed data analysis|Wrote or contributed to the writing of the manuscript	Wrote or contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
4418690	25938766	XHH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418690	25938766	YC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418690	25938766	YC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418690	25938766	YC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418690	25938766	YC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418690	25938766	YCZ	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418690	25938766	YCZ	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418690	25938766	YQX	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418690	25938766	YT	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4418690	25938766	YT	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418690	25938766	YX	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1995762	17925881	AM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1995762	17925881	BM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1995762	17925881	FO	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1995762	17925881	JW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1995762	17925881	JW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1995762	17925881	JW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1995762	17925881	MR	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1995762	17925881	QX	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Wrote the paper|Wrote the paper|Wrote the first draft of the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1995762	17925881	QX	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Wrote the paper|Wrote the paper|Wrote the first draft of the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1995762	17925881	QX	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Wrote the paper|Wrote the paper|Wrote the first draft of the paper	Performed the experiments	Performed the experiments	Investigation	YES
1995762	17925881	QX	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Wrote the paper|Wrote the paper|Wrote the first draft of the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1995762	17925881	QX	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Wrote the paper|Wrote the paper|Wrote the first draft of the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1995762	17925881	QX	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Wrote the paper|Wrote the paper|Wrote the first draft of the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1995762	17925881	QX	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Wrote the paper|Wrote the paper|Wrote the first draft of the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1995762	17925881	QX	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Wrote the paper|Wrote the paper|Wrote the first draft of the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1995762	17925881	QX	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Wrote the paper|Wrote the paper|Wrote the first draft of the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1995762	17925881	QX	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Wrote the paper|Wrote the paper|Wrote the first draft of the paper	Wrote the first draft of the paper	Wrote the paper	Writing - Original Draft	YES
1995762	17925881	SK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1995762	17925881	SK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1995762	17925881	SK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1995762	17925881	SP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1995762	17925881	SW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1995762	17925881	YH	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1995762	17925881	YH	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5928016	29713843	All authors	2	equally contributed to this work|read and approved the final manuscript	equally contributed to this work	-	-	NO
5928016	29713843	All authors	2	equally contributed to this work|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5928016	29713843	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5413871	28438912	All authors	2	reviewed and approved the final manuscript	reviewed and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5413871	28438912	C.M.	2	designed the review|contributed to the initial drafts and revisions of the manuscript	designed the review	Conceived and designed the experiments	-	YES
5413871	28438912	C.M.	2	designed the review|contributed to the initial drafts and revisions of the manuscript	contributed to the initial drafts and revisions of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5413871	28438912	D.B.A.T.	2	contributed to the initial drafts and revisions of the manuscript	contributed to the initial drafts and revisions of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5413871	28438912	J.M.	2	contributed to the initial drafts and revisions of the manuscript	contributed to the initial drafts and revisions of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5413871	28438912	K.H.	2	contributed to the initial drafts and revisions of the manuscript	contributed to the initial drafts and revisions of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5413871	28438912	L.G.	2	contributed to the initial drafts and revisions of the manuscript	contributed to the initial drafts and revisions of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5413871	28438912	R.B.	2	designed the review|contributed to the initial drafts and revisions of the manuscript	designed the review	Conceived and designed the experiments	-	YES
5413871	28438912	R.B.	2	designed the review|contributed to the initial drafts and revisions of the manuscript	contributed to the initial drafts and revisions of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5797395	29394882	AHN	1	Conception and design|Analysis and interpretation of data|Manuscript	Conception and design	Conceived and designed the experiments	Conceptualization	YES
5797395	29394882	AHN	1	Conception and design|Analysis and interpretation of data|Manuscript	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
5797395	29394882	AHN	1	Conception and design|Analysis and interpretation of data|Manuscript	Manuscript	-	-	NO
5797395	29394882	GFB	1	Analysis and interpretation of data|Manuscript	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
5797395	29394882	GFB	1	Analysis and interpretation of data|Manuscript	Manuscript	-	-	NO
5797395	29394882	JM	1	Acquisition of data	Acquisition of data	Performed the experiments	Investigation	YES
5797395	29394882	LZ	1	Conception and design|Acquisition of data|Analysis and interpretation of data|Manuscript	Conception and design	Conceived and designed the experiments	Conceptualization	YES
5797395	29394882	LZ	1	Conception and design|Acquisition of data|Analysis and interpretation of data|Manuscript	Acquisition of data	Performed the experiments	Investigation	YES
5797395	29394882	LZ	1	Conception and design|Acquisition of data|Analysis and interpretation of data|Manuscript	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
5797395	29394882	LZ	1	Conception and design|Acquisition of data|Analysis and interpretation of data|Manuscript	Manuscript	-	-	NO
5797395	29394882	MAS	1	Conception and design|Acquisition of data|Analysis and interpretation of data|Manuscript	Conception and design	Conceived and designed the experiments	Conceptualization	YES
5797395	29394882	MAS	1	Conception and design|Acquisition of data|Analysis and interpretation of data|Manuscript	Acquisition of data	Performed the experiments	Investigation	YES
5797395	29394882	MAS	1	Conception and design|Acquisition of data|Analysis and interpretation of data|Manuscript	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
5797395	29394882	MAS	1	Conception and design|Acquisition of data|Analysis and interpretation of data|Manuscript	Manuscript	-	-	NO
5797395	29394882	MSM	1	Conception and design|Acquisition of data|Analysis and interpretation of data|Manuscript	Conception and design	Conceived and designed the experiments	Conceptualization	YES
5797395	29394882	MSM	1	Conception and design|Acquisition of data|Analysis and interpretation of data|Manuscript	Acquisition of data	Performed the experiments	Investigation	YES
5797395	29394882	MSM	1	Conception and design|Acquisition of data|Analysis and interpretation of data|Manuscript	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
5797395	29394882	MSM	1	Conception and design|Acquisition of data|Analysis and interpretation of data|Manuscript	Manuscript	-	-	NO
5826387	29515597	AC	2	collected and analyzed the data	collected and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4983796	27529028	AO	2	helped to draft the manuscript	helped to draft the manuscript	Wrote the paper	Writing - Original Draft	YES
4983796	27529028	KMS	2	helped to draft the manuscript	helped to draft the manuscript	Wrote the paper	Writing - Original Draft	YES
1995763	17925862	AV	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
1995763	17925862	AV	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1995763	17925862	TR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1995763	17925862	TR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1995763	17925862	TR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1995763	17925862	TR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1995763	17925862	TR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3980203	24704990	APK	2	critical revisions	critical revisions	Wrote the paper	Writing - Review & Editing	YES
3980203	24704990	CDAS	2	acquisition of data	acquisition of data	Performed the experiments	Investigation	YES
3980203	24704990	DGBA	2	acquisition, analysis and data interpretation	acquisition, analysis and data interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3980203	24704990	ESG	2	acquisition, analysis and data interpretation	acquisition, analysis and data interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3980203	24704990	LN	2	substantial contributions to conception and design|final approval of the version to be published	substantial contributions to conception and design	Conceived and designed the experiments	Conceptualization	YES
3980203	24704990	LN	2	substantial contributions to conception and design|final approval of the version to be published	final approval of the version to be published	-	-	NO
3980203	24704990	MO	2	analysis and data interpretation	analysis and data interpretation	Analyzed the data	Formal analysis	YES
3980203	24704990	PG	2	acquisition of data	acquisition of data	Performed the experiments	Investigation	YES
3980203	24704990	VB	2	acquisition of data	acquisition of data	Performed the experiments	Investigation	YES
6270831	25093986	F.W.	7	review of the manuscript	review of the manuscript	Wrote the paper	Writing - Review & Editing	YES
6270831	25093986	J.J.S.	7	manuscript preparation	manuscript preparation	Wrote the paper	Writing - Original Draft	YES
6270831	25093986	J.K.X.	7	conception, design, and manuscript preparation	conception, design, and manuscript preparation	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
6270831	25093986	J.S.	7	review of the manuscript	review of the manuscript	Wrote the paper	Writing - Review & Editing	YES
6270831	25093986	M.S.	7	conception and review of the manuscript	conception and review of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
6270831	25093986	Y.J.W.	7	review of the manuscript	review of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4418691	25938495	GHP	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418691	25938495	KBK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418691	25938495	KBK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418691	25938495	KBK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418691	25938495	KBK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418691	25938495	KPK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418691	25938495	KPK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418691	25938495	KPK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418691	25938495	KPK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418691	25938495	KYK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418691	25938495	KYK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418691	25938495	KYK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418691	25938495	KYK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418691	25938495	MSL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418691	25938495	MSL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418691	25938495	MSL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418691	25938495	MSL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418691	25938495	MY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418691	25938495	MY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418691	25938495	MY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418691	25938495	MY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5799908	29402217	CDD	2	developed bioinformatics methods and analysed data|wrote the manuscript and all authors reviewed it	developed bioinformatics methods and analysed data	Performed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5799908	29402217	CDD	2	developed bioinformatics methods and analysed data|wrote the manuscript and all authors reviewed it	wrote the manuscript and all authors reviewed it	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5799908	29402217	CT	2	wrote the manuscript and all authors reviewed it	wrote the manuscript and all authors reviewed it	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5799908	29402217	DN	2	analysed data	analysed data	Analyzed the data	Formal analysis	YES
5799908	29402217	EVD	2	designed, planned and performed the experiments|wrote the manuscript and all authors reviewed it	designed, planned and performed the experiments	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
5799908	29402217	EVD	2	designed, planned and performed the experiments|wrote the manuscript and all authors reviewed it	wrote the manuscript and all authors reviewed it	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5799908	29402217	KA	2	through helpful discussions|performed plant rna extractions	through helpful discussions	-	-	NO
5799908	29402217	KA	2	through helpful discussions|performed plant rna extractions	performed plant rna extractions	Performed the experiments	Investigation	YES
5799908	29402217	YAC	2	through helpful discussions	through helpful discussions	-	-	NO
5413873	28438914	A.V.	2	contributed the peruvian data described in the paper|edited and revised the manuscript	contributed the peruvian data described in the paper	Contributed reagents/materials/analysis tools	Resources	YES
5413873	28438914	A.V.	2	contributed the peruvian data described in the paper|edited and revised the manuscript	edited and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5413873	28438914	D.V.	2	analysed the data, prepared the corresponding figures and contributed to the ideas and framework of the paper|edited and revised the manuscript	analysed the data, prepared the corresponding figures and contributed to the ideas and framework of the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Visualization|Writing - Original Draft	YES
5413873	28438914	D.V.	2	analysed the data, prepared the corresponding figures and contributed to the ideas and framework of the paper|edited and revised the manuscript	edited and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5413873	28438914	J.M.T.L.	2	performed the systematic literature review and wrote the majority of the initial draft|edited and revised the manuscript	performed the systematic literature review and wrote the majority of the initial draft	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5413873	28438914	J.M.T.L.	2	performed the systematic literature review and wrote the majority of the initial draft|edited and revised the manuscript	edited and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5413873	28438914	LULC	2	classification in figure 2	classification in figure 2	-	Visualization	YES
5413873	28438914	S.R.	2	edited and revised the manuscript	edited and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4983797	27529029	NT	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4983797	27529029	TK	2	wrote the manuscript and revised the manuscript	wrote the manuscript and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5931955	29721735	All authors	2	read and approved the manuscript	read and approved the manuscript	-	-	NO
5931955	29721735	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5931955	29721735	WJ	2	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5931955	29721735	WQY	2	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5931955	29721735	XDX	2	performed the experiments and wrote the manuscript	performed the experiments and wrote the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5931955	29721735	YJ	2	reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5931955	29721735	ZX	2	reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
1995764	17925864	AC	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1995764	17925864	AM	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1995764	17925864	CF	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1995764	17925864	CR	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1995764	17925864	ED	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1995764	17925864	FL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1995764	17925864	GV	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
1995764	17925864	JJ	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1995764	17925864	JJ	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1995764	17925864	KA	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1995764	17925864	KB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
1995764	17925864	MF	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1995764	17925864	NG	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1995764	17925864	NG	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
1995764	17925864	RM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1995764	17925864	RM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1995764	17925864	RM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1995764	17925864	RM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3980204	24704991	CG	2	data interpretation	data interpretation	Analyzed the data	Formal analysis	YES
3980204	24704991	DF	2	data analysis|data interpretation	data analysis	Analyzed the data	Formal analysis	YES
3980204	24704991	DF	2	data analysis|data interpretation	data interpretation	Analyzed the data	Formal analysis	YES
3980204	24704991	EDF	2	data analysis	data analysis	Analyzed the data	Formal analysis	YES
3980204	24704991	GF	2	preparation of the manuscript|critical revision of the manuscript	preparation of the manuscript	Wrote the paper	Writing - Original Draft	YES
3980204	24704991	GF	2	preparation of the manuscript|critical revision of the manuscript	critical revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
3980204	24704991	IM	2	critical revision of the manuscript	critical revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
3980204	24704991	MC	2	critical revision of the manuscript	critical revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
3980204	24704991	PVE	2	critical revision of the manuscript	critical revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
3980204	24704991	SN	2	data analysis|data interpretation	data analysis	Analyzed the data	Formal analysis	YES
3980204	24704991	SN	2	data analysis|data interpretation	data interpretation	Analyzed the data	Formal analysis	YES
3980204	24704991	TC	2	data analysis	data analysis	Analyzed the data	Formal analysis	YES
3980204	24704991	WT	2	preparation of the manuscript|data analysis|data interpretation	preparation of the manuscript	Wrote the paper	Writing - Original Draft	YES
3980204	24704991	WT	2	preparation of the manuscript|data analysis|data interpretation	data analysis	Analyzed the data	Formal analysis	YES
3980204	24704991	WT	2	preparation of the manuscript|data analysis|data interpretation	data interpretation	Analyzed the data	Formal analysis	YES
4418692	25938461	AL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418692	25938461	AMS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418692	25938461	AMS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418692	25938461	AMS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418692	25938461	CAH	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418692	25938461	CAH	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418692	25938461	CMP	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418692	25938461	EBO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418692	25938461	EBO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418692	25938461	EBO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418692	25938461	EBO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418692	25938461	JL	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418692	25938461	LNS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418692	25938461	MJF	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418692	25938461	MN	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418692	25938461	NED	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418692	25938461	NED	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418692	25938461	NED	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418692	25938461	OS	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418692	25938461	PL	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418692	25938461	YL	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418692	25938461	ZL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418692	25938461	ZL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418692	25938461	ZL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418692	25938461	ZL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5826952	29520284	All authors	2	participated in discussing the focus, data to select, analyse and present this data in tables, describing results and putting it to discussion	participated in discussing the focus, data to select, analyse and present this data in tables, describing results and putting it to discussion	Analyzed the data	Formal analysis	YES
5800017	29402222	ARG	2	was responsible for patient management and writing	was responsible for patient management and writing	Wrote the paper	-	YES
5800017	29402222	AvL	2	was responsible for conceptualization and writing	was responsible for conceptualization and writing	Conceived and designed the experiments|Wrote the paper	Conceptualization	YES
5800017	29402222	BA	2	was responsible for funding acquisition, project administration, resources, and supervision	was responsible for funding acquisition, project administration, resources, and supervision	Contributed reagents/materials/analysis tools	Funding acquisition|Project administration|Resources|Supervision	YES
5800017	29402222	BED	2	was responsible for conceptualization, data analysis, methodology, supervision, and writing	was responsible for conceptualization, data analysis, methodology, supervision, and writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Supervision	YES
5800017	29402222	CR	2	was responsible for conceptualization, data analysis, funding acquisition, and writing	was responsible for conceptualization, data analysis, funding acquisition, and writing	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Funding acquisition	YES
5800017	29402222	HNG	2	was responsible for conceptualization and methodological guidance	was responsible for conceptualization and methodological guidance	Conceived and designed the experiments|Performed the experiments	Conceptualization|Methodology|Supervision	YES
5800017	29402222	LC	2	was responsible for laboratory management, project administration, resources, and writing	was responsible for laboratory management, project administration, resources, and writing	Contributed reagents/materials/analysis tools|Wrote the paper	Project administration|Resources	YES
5800017	29402222	MAH	2	was responsible for conceptualization, methodology, resources, supervision, and writing	was responsible for conceptualization, methodology, resources, supervision, and writing	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Methodology|Resources|Supervision	YES
5800017	29402222	RvC	2	was responsible for conceptualization, funding acquisition, project administration, supervision, and writing	was responsible for conceptualization, funding acquisition, project administration, supervision, and writing	Conceived and designed the experiments|Wrote the paper	Conceptualization|Funding acquisition|Project administration|Supervision	YES
5800017	29402222	SD	2	was responsible for inclusion of patients in the study and writing	was responsible for inclusion of patients in the study and writing	Wrote the paper	-	YES
5413875	28438916	A.K.	2	acquired data, assisted with arcgis and helped draft the manuscript	acquired data, assisted with arcgis and helped draft the manuscript	Performed the experiments|Wrote the paper	Investigation|Software|Writing - Original Draft	YES
5413875	28438916	A.L.	2	helped draft the manuscript	helped draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5413875	28438916	A.M.K.	2	helped draft the manuscript	helped draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5413875	28438916	All authors	2	gave final approval for publication	gave final approval for publication	-	-	NO
5413875	28438916	C.L.W.	2	helped draft the manuscript	helped draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5413875	28438916	C.M.H.	2	helped draft the manuscript	helped draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5413875	28438916	D.L.	2	acquired data, assisted with arcgis and helped draft the manuscript	acquired data, assisted with arcgis and helped draft the manuscript	Performed the experiments|Wrote the paper	Investigation|Software|Writing - Original Draft	YES
5413875	28438916	D.L.-C.	2	helped draft the manuscript	helped draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5413875	28438916	G.A.D.L.	2	helped draft the manuscript	helped draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5413875	28438916	I.J.J.	2	acquired data, assisted with arcgis and helped draft the manuscript	acquired data, assisted with arcgis and helped draft the manuscript	Performed the experiments|Wrote the paper	Investigation|Software|Writing - Original Draft	YES
5413875	28438916	J.F.	2	acquired data, assisted with arcgis and helped draft the manuscript	acquired data, assisted with arcgis and helped draft the manuscript	Performed the experiments|Wrote the paper	Investigation|Software|Writing - Original Draft	YES
5413875	28438916	J.R.	2	helped draft the manuscript	helped draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5413875	28438916	K.D.L.	2	helped draft the manuscript	helped draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5413875	28438916	M.J.	2	helped draft the manuscript	helped draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5413875	28438916	O.C.	2	acquired data, assisted with arcgis and helped draft the manuscript	acquired data, assisted with arcgis and helped draft the manuscript	Performed the experiments|Wrote the paper	Investigation|Software|Writing - Original Draft	YES
5413875	28438916	P.A.C.	2	helped draft the manuscript	helped draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5413875	28438916	S.H.S.	2	conceived, designed and coordinated the study, acquired data, carried out the statistical analysis and wrote the manuscript	conceived, designed and coordinated the study, acquired data, carried out the statistical analysis and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Project administration|Writing - Original Draft	YES
3598077	23341130	ARC	2	provided intellectual input to the chemical and modelling studies	provided intellectual input to the chemical and modelling studies	Performed the experiments	Methodology	YES
3598077	23341130	CFC	2	designed and performed cellular experiments	designed and performed cellular experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3598077	23341130	CMH	2	designed and performed cellular experiments	designed and performed cellular experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3598077	23341130	CML	2	resistant to tyrosine kinase inhibitors	resistant to tyrosine kinase inhibitors	-	-	NO
3598077	23341130	EG	2	designed and performed cellular experiments	designed and performed cellular experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3598077	23341130	GL	2	designed and performed cellular experiments	designed and performed cellular experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3598077	23341130	GW	2	designed and performed cellular experiments|performed the compound pull-down and ubiquitination assays	designed and performed cellular experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3598077	23341130	GW	2	designed and performed cellular experiments|performed the compound pull-down and ubiquitination assays	performed the compound pull-down and ubiquitination assays	Performed the experiments	Investigation	YES
3598077	23341130	HK	2	designed and performed cellular experiments	designed and performed cellular experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3598077	23341130	JZ	2	designed and synthesized the compounds|performed the molecular modelling, gel filtration assay and in vitro binding assays|wrote the paper with input from all co-authors	designed and synthesized the compounds	Conceived and designed the experiments|Performed the experiments	Investigation	YES
3598077	23341130	JZ	2	designed and synthesized the compounds|performed the molecular modelling, gel filtration assay and in vitro binding assays|wrote the paper with input from all co-authors	performed the molecular modelling, gel filtration assay and in vitro binding assays	Performed the experiments	Investigation|Methodology	YES
3598077	23341130	JZ	2	designed and synthesized the compounds|performed the molecular modelling, gel filtration assay and in vitro binding assays|wrote the paper with input from all co-authors	wrote the paper with input from all co-authors	Wrote the paper	Writing - Original Draft	YES
3598077	23341130	LZ	2	designed and performed cellular experiments|designed and performed animal studies	designed and performed cellular experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3598077	23341130	LZ	2	designed and performed cellular experiments|designed and performed animal studies	designed and performed animal studies	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3598077	23341130	PLC	2	designed and performed the high-throughput screening|provided critical input to the overall research direction	designed and performed the high-throughput screening	Conceived and designed the experiments|Performed the experiments	Investigation	YES
3598077	23341130	PLC	2	designed and performed the high-throughput screening|provided critical input to the overall research direction	provided critical input to the overall research direction	-	-	NO
3598077	23341130	RNA	2	suggesting the mode of action of the compound is specific to rad51	suggesting the mode of action of the compound is specific to rad51	Performed the experiments	Investigation	YES
3598077	23341130	WHL	2	provided critical input to the overall research direction|wrote the paper with input from all co-authors	provided critical input to the overall research direction	-	-	NO
3598077	23341130	WHL	2	provided critical input to the overall research direction|wrote the paper with input from all co-authors	wrote the paper with input from all co-authors	Wrote the paper	Writing - Original Draft	YES
3598077	23341130	XL	2	designed and performed cellular experiments	designed and performed cellular experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3598077	23341130	XLQ	2	designed and synthesized the compounds	designed and synthesized the compounds	Conceived and designed the experiments|Performed the experiments	Investigation	YES
3980205	24704992	JHS	2	contributed equally to this work	contributed equally to this work	-	-	NO
3980205	24704992	MYL	2	contributed equally to this work	contributed equally to this work	-	-	NO
5931956	29721676	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5931956	29721676	HD	PLoS52	performed the research and wrote the paper	performed the research and wrote the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5931956	29721676	RG	PLoS52	performed the research and wrote the paper|analyzed the data	performed the research and wrote the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5931956	29721676	RG	PLoS52	performed the research and wrote the paper|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5931956	29721676	XL	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5931956	29721676	YC	PLoS52	designed the research|analyzed the data	designed the research	Conceived and designed the experiments	Methodology	YES
5931956	29721676	YC	PLoS52	designed the research|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5931956	29721676	ZG	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
1999654	17925856	AL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1999654	17925856	AL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1999654	17925856	AL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1999654	17925856	AL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1999654	17925856	BP	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1999654	17925856	BP	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1999654	17925856	JR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1999654	17925856	JR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1999654	17925856	JR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1999654	17925856	JR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
1999654	17925856	LS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
1999654	17925856	LS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
1999654	17925856	LS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
1999654	17925856	LS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418693	25938584	AGT	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418693	25938584	AS	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418693	25938584	HK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418693	25938584	HK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418693	25938584	HK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418693	25938584	HK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418693	25938584	HO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418693	25938584	HO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418693	25938584	HO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418693	25938584	HO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418693	25938584	KT	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418693	25938584	KT	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418693	25938584	MS	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418693	25938584	MS	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418693	25938584	MTI	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418693	25938584	PPA	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418693	25938584	RT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418693	25938584	RT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418693	25938584	RT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418693	25938584	RT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418693	25938584	SL	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418693	25938584	TK	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418693	25938584	VT	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6270833	24962400	A.O.	2	have made intellectual contributions and given the final approval for the manuscript to be published	have made intellectual contributions and given the final approval for the manuscript to be published	-	-	NO
6270833	24962400	C.P.T.	2	have critically reviewed the content of this manuscript	have critically reviewed the content of this manuscript	Wrote the paper	Writing - Review & Editing	YES
6270833	24962400	H.M.	2	have critically reviewed the content of this manuscript	have critically reviewed the content of this manuscript	Wrote the paper	Writing - Review & Editing	YES
6270833	24962400	K.W.C.	2	carried out all the experiments, data analysis and interpretation of data	carried out all the experiments, data analysis and interpretation of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270833	24962400	M.B.	2	have critically reviewed the content of this manuscript	have critically reviewed the content of this manuscript	Wrote the paper	Writing - Review & Editing	YES
6270833	24962400	N.S.A.H.	2	have made intellectual contributions and given the final approval for the manuscript to be published	have made intellectual contributions and given the final approval for the manuscript to be published	-	-	NO
5826958	29520286	FC	PLoS52	performed the research	performed the research	Performed the experiments	Investigation	YES
5826958	29520286	FN	PLoS52	designed the research|performed the research|analyzed the data|wrote the paper	designed the research	Conceived and designed the experiments	Methodology	YES
5826958	29520286	FN	PLoS52	designed the research|performed the research|analyzed the data|wrote the paper	performed the research	Performed the experiments	Investigation	YES
5826958	29520286	FN	PLoS52	designed the research|performed the research|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5826958	29520286	FN	PLoS52	designed the research|performed the research|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5826958	29520286	FZ	PLoS52	designed the research|revised the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
5826958	29520286	FZ	PLoS52	designed the research|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5826958	29520286	JH	PLoS52	performed the research	performed the research	Performed the experiments	Investigation	YES
5826958	29520286	QS	PLoS52	performed the research	performed the research	Performed the experiments	Investigation	YES
5826958	29520286	RW	PLoS52	performed the research	performed the research	Performed the experiments	Investigation	YES
5826958	29520286	XD	PLoS52	designed the research|revised the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
5826958	29520286	XD	PLoS52	designed the research|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5826958	29520286	XL	PLoS52	designed the research|analyzed the data|wrote the paper	designed the research	Conceived and designed the experiments	Methodology	YES
5826958	29520286	XL	PLoS52	designed the research|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5826958	29520286	XL	PLoS52	designed the research|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5826958	29520286	ZA	PLoS52	performed the research	performed the research	Performed the experiments	Investigation	YES
5800023	29402227	DSH	2	supervised the study, wrote the manuscript and tested the web interface	supervised the study, wrote the manuscript and tested the web interface	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Software|Supervision|Writing - Original Draft	YES
5800023	29402227	EP	2	supervised the study and wrote the manuscript	supervised the study and wrote the manuscript	Wrote the paper	Supervision|Writing - Original Draft	YES
5800023	29402227	FZ	2	supervised the study, wrote the manuscript and tested the web interface	supervised the study, wrote the manuscript and tested the web interface	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Software|Supervision|Writing - Original Draft	YES
5800023	29402227	GC	2	contributed to the development and testing of the variant calling pipeline and deployment on the cloud infrastructure	contributed to the development and testing of the variant calling pipeline and deployment on the cloud infrastructure	Performed the experiments	Investigation	YES
5800023	29402227	MD	2	supervised the deployment of the pipeline on the cloud and implementation of the web interface	supervised the deployment of the pipeline on the cloud and implementation of the web interface	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software|Supervision	YES
5800023	29402227	SG	2	contributed to the development and testing of the variant calling pipeline and deployment on the cloud infrastructure	contributed to the development and testing of the variant calling pipeline and deployment on the cloud infrastructure	Performed the experiments	Investigation	YES
5800023	29402227	TC	2	supervised the development and testing of the variant calling pipeline, wrote the manuscript	supervised the development and testing of the variant calling pipeline, wrote the manuscript	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Original Draft	YES
5800023	29402227	TF	2	contributed to the development and testing of the variant calling pipeline and deployment on the cloud infrastructure	contributed to the development and testing of the variant calling pipeline and deployment on the cloud infrastructure	Performed the experiments	Investigation	YES
5800023	29402227	VaCS	2	supervised the study, wrote the manuscript	supervised the study, wrote the manuscript	Wrote the paper	Supervision|Writing - Original Draft	YES
5935602	29728880	AP	PLoS52	contributed to performing bioconversion experiments	contributed to performing bioconversion experiments	Performed the experiments	Investigation	YES
5935602	29728880	All	PLoS52	data generated or analyzed during this study are included in this published article and its additional file	data generated or analyzed during this study are included in this published article and its additional file	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5935602	29728880	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5935602	29728880	DAC	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5935602	29728880	The authors	PLoS52	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5935602	29728880	VF	PLoS52	conceived the work and wrote the manuscript	conceived the work and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
3598078	23381944	AAV	2	performed molecular experiments specific to mammalian cell culture and tumour xenografts, performed data analysis and helped write the manuscript	performed molecular experiments specific to mammalian cell culture and tumour xenografts, performed data analysis and helped write the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3598078	23381944	AP	2	helped design yeast experiments, constructed strains and performed viability analysis and helped write the manuscript	helped design yeast experiments, constructed strains and performed viability analysis and helped write the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
3598078	23381944	CTYC	2	measured trna modification levels, contributed to experimental design and helped write the manuscript	measured trna modification levels, contributed to experimental design and helped write the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
3598078	23381944	DS	2	measured trna modification levels, contributed to experimental design and helped write the manuscript	measured trna modification levels, contributed to experimental design and helped write the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
3598078	23381944	JAAG	2	contributed to experimental design, data analysis, discussed results and helped write the manuscript	contributed to experimental design, data analysis, discussed results and helped write the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
3598078	23381944	LE	2	performed molecular experiments specific to cancer cells, performed data analysis and helped write the manuscript	performed molecular experiments specific to cancer cells, performed data analysis and helped write the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3598078	23381944	MSS	2	performed molecular experiments specific to mammalian cell culture and tumour xenografts, performed data analysis and helped write the manuscript	performed molecular experiments specific to mammalian cell culture and tumour xenografts, performed data analysis and helped write the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3598078	23381944	PCD	2	contributed to experimental design, data analysis, discussed results and helped write the manuscript	contributed to experimental design, data analysis, discussed results and helped write the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
3598078	23381944	TB	2	contributed to experimental design, data analysis, discussed results and helped write the manuscript	contributed to experimental design, data analysis, discussed results and helped write the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
3598078	23381944	UB	2	constructed human cell lines, performed molecular and protein-based experiments specific to cell culture and tumour xenografts, performed data analysis and helped write the manuscript	constructed human cell lines, performed molecular and protein-based experiments specific to cell culture and tumour xenografts, performed data analysis and helped write the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3598078	23381944	YE	2	performed molecular experiments specific to mammalian cell culture and tumour xenografts, performed data analysis and helped write the manuscript	performed molecular experiments specific to mammalian cell culture and tumour xenografts, performed data analysis and helped write the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
2000348	17925869	SF	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418694	25938298	AK	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4418694	25938298	AK	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418694	25938298	AKS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418694	25938298	AKS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418694	25938298	AKS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418694	25938298	BGL	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418694	25938298	BM	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418694	25938298	BM	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418694	25938298	MKE	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418694	25938298	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418694	25938298	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418694	25938298	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418694	25938298	SK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418694	25938298	VS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
3980206	24704993	DZ	2	experimental arrangement and design	experimental arrangement and design	Conceived and designed the experiments	Methodology	YES
3980206	24704993	HZ	2	data collection	data collection	Performed the experiments	Investigation	YES
3980206	24704993	JL	2	equal contribution to the present article|experiment performing	equal contribution to the present article	-	-	NO
3980206	24704993	JL	2	equal contribution to the present article|experiment performing	experiment performing	Performed the experiments	Investigation	YES
3980206	24704993	JN	2	experiment performing	experiment performing	Performed the experiments	Investigation	YES
3980206	24704993	JX	2	experimental arrangement and design	experimental arrangement and design	Conceived and designed the experiments	Methodology	YES
3980206	24704993	JZ	2	equal contribution to the present article|experiment performing and manuscript writing	equal contribution to the present article	-	-	NO
3980206	24704993	JZ	2	equal contribution to the present article|experiment performing and manuscript writing	experiment performing and manuscript writing	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3980206	24704993	LT	2	data collection	data collection	Performed the experiments	Investigation	YES
3980206	24704993	LZ	2	data analysis	data analysis	Analyzed the data	Formal analysis	YES
6270834	25054444	C.M.S.T.	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
6270834	25054444	H.B.C.	2	initiated and designed the study	initiated and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6270834	25054444	J.Y.F.	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
6270834	25054444	L.Z.	2	were involved in the revision of the manuscript	were involved in the revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
6270834	25054444	T.Y.	2	initiated and designed the study	initiated and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6270834	25054444	W.L.P.	2	were involved in the revision of the manuscript	were involved in the revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
6270834	25054444	Y.Z.Z.	2	contributed to literatures collection	contributed to literatures collection	-	Formal analysis	YES
6270834	25054444	Z.Z.Z.	2	contributed to literatures collection	contributed to literatures collection	-	Formal analysis	YES
5009638	27595002	All authors	2	did research and assisted tt to write this paper	did research and assisted tt to write this paper	Wrote the paper	Writing - Original Draft	YES
5009638	27595002	YT	2	on top of assisting the authors with research, provided guidance	on top of assisting the authors with research, provided guidance	-	Supervision	YES
5826962	29520292	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5434095	28483874	All authors	2	gave final approval for publication	gave final approval for publication	-	-	NO
5434095	28483874	C.D.	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5434095	28483874	C.D.T.	2	designed the study|drafted the manuscript, and all authors contributed to revising the paper	designed the study	Conceived and designed the experiments	Methodology	YES
5434095	28483874	C.D.T.	2	designed the study|drafted the manuscript, and all authors contributed to revising the paper	drafted the manuscript, and all authors contributed to revising the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5434095	28483874	G.P.	2	designed the study|carried out the analyses|drafted the manuscript, and all authors contributed to revising the paper	designed the study	Conceived and designed the experiments	Methodology	YES
5434095	28483874	G.P.	2	designed the study|carried out the analyses|drafted the manuscript, and all authors contributed to revising the paper	carried out the analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5434095	28483874	G.P.	2	designed the study|carried out the analyses|drafted the manuscript, and all authors contributed to revising the paper	drafted the manuscript, and all authors contributed to revising the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5434095	28483874	J.K.H.	2	designed the study|drafted the manuscript, and all authors contributed to revising the paper	designed the study	Conceived and designed the experiments	Methodology	YES
5434095	28483874	J.K.H.	2	designed the study|drafted the manuscript, and all authors contributed to revising the paper	drafted the manuscript, and all authors contributed to revising the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5434095	28483874	P.J.P.	2	designed the study|carried out the analyses|drafted the manuscript, and all authors contributed to revising the paper	designed the study	Conceived and designed the experiments	Methodology	YES
5434095	28483874	P.J.P.	2	designed the study|carried out the analyses|drafted the manuscript, and all authors contributed to revising the paper	carried out the analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5434095	28483874	P.J.P.	2	designed the study|carried out the analyses|drafted the manuscript, and all authors contributed to revising the paper	drafted the manuscript, and all authors contributed to revising the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
2000350	17925863	FC	PLoS5	Performed the experiments|Analyzed the data|Analyzed the data|Wrote the paper|Assisted with manuscript preparation	Performed the experiments	Performed the experiments	Investigation	YES
2000350	17925863	FC	PLoS5	Performed the experiments|Analyzed the data|Analyzed the data|Wrote the paper|Assisted with manuscript preparation	Analyzed the data	Analyzed the data	Formal analysis	YES
2000350	17925863	FC	PLoS5	Performed the experiments|Analyzed the data|Analyzed the data|Wrote the paper|Assisted with manuscript preparation	Analyzed the data	Analyzed the data	Formal analysis	YES
2000350	17925863	FC	PLoS5	Performed the experiments|Analyzed the data|Analyzed the data|Wrote the paper|Assisted with manuscript preparation	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2000350	17925863	FC	PLoS5	Performed the experiments|Analyzed the data|Analyzed the data|Wrote the paper|Assisted with manuscript preparation	Assisted with manuscript preparation	Wrote the paper	Writing - Original Draft	YES
2000350	17925863	GL	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2000350	17925863	GL	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2000350	17925863	LB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
2000350	17925863	PP	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2000350	17925863	PP	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2000350	17925863	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2000350	17925863	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2000350	17925863	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2000350	17925863	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2000350	17925863	SP	PLoS5	Performed the experiments|Assisted with manuscript preparation	Performed the experiments	Performed the experiments	Investigation	YES
2000350	17925863	SP	PLoS5	Performed the experiments|Assisted with manuscript preparation	Assisted with manuscript preparation	Wrote the paper	Writing - Original Draft	YES
5800051	29402214	AB	2	generated part of the f2 genomic sequences	generated part of the f2 genomic sequences	Performed the experiments	Investigation	YES
5800051	29402214	AC	2	acquired the funding and corrected the manuscript	acquired the funding and corrected the manuscript	Wrote the paper	Funding acquisition|Writing - Review & Editing	YES
5800051	29402214	AD	2	carried out de novo f2 genome assembly, snp detection	carried out de novo f2 genome assembly, snp detection	Performed the experiments	Investigation	YES
5800051	29402214	CV	2	carried out genome size experiment, supervised f2 illumina sequence data generation, analyzed results and drafted the manuscript|acquired the funding and corrected the manuscript	carried out genome size experiment, supervised f2 illumina sequence data generation, analyzed results and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Supervision|Writing - Original Draft	YES
5800051	29402214	CV	2	carried out genome size experiment, supervised f2 illumina sequence data generation, analyzed results and drafted the manuscript|acquired the funding and corrected the manuscript	acquired the funding and corrected the manuscript	Wrote the paper	Funding acquisition|Writing - Review & Editing	YES
5800051	29402214	JJ	2	carried out targeted f2 genome assembly|acquired the funding and corrected the manuscript	carried out targeted f2 genome assembly	Performed the experiments	Investigation	YES
5800051	29402214	JJ	2	carried out targeted f2 genome assembly|acquired the funding and corrected the manuscript	acquired the funding and corrected the manuscript	Wrote the paper	Funding acquisition|Writing - Review & Editing	YES
5800051	29402214	LD	2	analyses, group frequency analyses, supervised all the analyses, analyzed results and drafted the manuscript	analyses, group frequency analyses, supervised all the analyses, analyzed results and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Supervision|Writing - Original Draft	YES
5800051	29402214	MCLP	2	generated part of the f2 genomic sequences	generated part of the f2 genomic sequences	Performed the experiments	Investigation	YES
5800051	29402214	PAV	2	detection and annotation, and built the b73/f2 pan-genome|detection and annotation, mrna seq analyses	detection and annotation, and built the b73/f2 pan-genome	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5800051	29402214	PAV	2	detection and annotation, and built the b73/f2 pan-genome|detection and annotation, mrna seq analyses	detection and annotation, mrna seq analyses	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5800051	29402214	PAVs	2	in maize and other grasses	in maize and other grasses	-	-	NO
5800051	29402214	PR	2	carried out plant growth for transcriptome analyses, rna extractions and supervised generation of mrna seq data|acquired the funding and corrected the manuscript	carried out plant growth for transcriptome analyses, rna extractions and supervised generation of mrna seq data	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Supervision	YES
5800051	29402214	PR	2	carried out plant growth for transcriptome analyses, rna extractions and supervised generation of mrna seq data|acquired the funding and corrected the manuscript	acquired the funding and corrected the manuscript	Wrote the paper	Funding acquisition|Writing - Review & Editing	YES
5800051	29402214	SN	2	participated in snp validation using 50 k array|acquired the funding and corrected the manuscript	participated in snp validation using 50 k array	Performed the experiments	Investigation|Validation	YES
5800051	29402214	SN	2	participated in snp validation using 50 k array|acquired the funding and corrected the manuscript	acquired the funding and corrected the manuscript	Wrote the paper	Funding acquisition|Writing - Review & Editing	YES
5800051	29402214	SV	2	discovery methodologies	discovery methodologies	Performed the experiments	Methodology	YES
3980207	24704994	JMO	2	contribute equally to this work	contribute equally to this work	-	-	NO
3980207	24704994	YBL	2	experimental arrangement	experimental arrangement	-	-	NO
3980207	24704994	ZF	2	experimental arrangement and design	experimental arrangement and design	Conceived and designed the experiments	Methodology	YES
3980207	24704994	ZWQ	2	data analysis, other authors, data collection	data analysis, other authors, data collection	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3980207	24704994	ZYY	2	contribute equally to this work|experiment performing	contribute equally to this work	-	-	NO
3980207	24704994	ZYY	2	contribute equally to this work|experiment performing	experiment performing	Performed the experiments	Investigation	YES
3598079	23495140	AK	2	conducted experiments including western blotting and qrt pcr|helped in mouse work	conducted experiments including western blotting and qrt pcr	Performed the experiments	Investigation	YES
3598079	23495140	AK	2	conducted experiments including western blotting and qrt pcr|helped in mouse work	helped in mouse work	Performed the experiments	Investigation	YES
3598079	23495140	AW	2	provided key experimental reagents and experimental advice	provided key experimental reagents and experimental advice	Contributed reagents/materials/analysis tools	Resources	YES
3598079	23495140	BEM	2	performed immunohistochemistry and provided pathological review	performed immunohistochemistry and provided pathological review	Performed the experiments	Investigation	YES
3598079	23495140	EP	2	performed immunohistochemistry and provided pathological review	performed immunohistochemistry and provided pathological review	Performed the experiments	Investigation	YES
3598079	23495140	FX	2	developed the hypotheses, designed the experiments and wrote the manuscript|performed most experiments and analysed data	developed the hypotheses, designed the experiments and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
3598079	23495140	FX	2	developed the hypotheses, designed the experiments and wrote the manuscript|performed most experiments and analysed data	performed most experiments and analysed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3598079	23495140	HO	2	helped in clinical cohort data analysis|helped in mouse work	helped in clinical cohort data analysis	Analyzed the data	Formal analysis	YES
3598079	23495140	HO	2	helped in clinical cohort data analysis|helped in mouse work	helped in mouse work	Performed the experiments	Investigation	YES
3598079	23495140	KF	2	helped in mouse work	helped in mouse work	Performed the experiments	Investigation	YES
3598079	23495140	KW	2	developed the hypotheses, designed the experiments and wrote the manuscript|helped in mouse work|directed this study	developed the hypotheses, designed the experiments and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
3598079	23495140	KW	2	developed the hypotheses, designed the experiments and wrote the manuscript|helped in mouse work|directed this study	helped in mouse work	Performed the experiments	Investigation	YES
3598079	23495140	KW	2	developed the hypotheses, designed the experiments and wrote the manuscript|helped in mouse work|directed this study	directed this study	-	Supervision	YES
3598079	23495140	MI	2	conducted experiments including western blotting and qrt pcr	conducted experiments including western blotting and qrt pcr	Performed the experiments	Investigation	YES
3598079	23495140	MW	2	provided technical support in tissue culture	provided technical support in tissue culture	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
3598079	23495140	PRP	2	assisted with generation of lenti virus expression plasmids	assisted with generation of lenti virus expression plasmids	Performed the experiments	Investigation	YES
3598079	23495140	SH	2	provided breast cancer patients specimens and pathological review	provided breast cancer patients specimens and pathological review	Performed the experiments	Investigation	YES
3598079	23495140	SKP	2	performed immunohistochemistry and provided pathological review	performed immunohistochemistry and provided pathological review	Performed the experiments	Investigation	YES
3598079	23495140	SS	2	provided technical support in tissue culture|helped in mouse work	provided technical support in tissue culture	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
3598079	23495140	SS	2	provided technical support in tissue culture|helped in mouse work	helped in mouse work	Performed the experiments	Investigation	YES
3598079	23495140	WL	2	helped in mouse work	helped in mouse work	Performed the experiments	Investigation	YES
3598079	23495140	YL	2	helped in mouse work	helped in mouse work	Performed the experiments	Investigation	YES
3598079	23495140	YYM	2	provided key experimental reagents and experimental advice	provided key experimental reagents and experimental advice	Contributed reagents/materials/analysis tools	Resources	YES
4418695	25938421	AMD	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418695	25938421	CJ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418695	25938421	CT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418695	25938421	CT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418695	25938421	CT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418695	25938421	H-GK	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418695	25938421	IN	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418695	25938421	J-MS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418695	25938421	MR	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418695	25938421	NA	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418695	25938421	RP	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418695	25938421	RP	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418695	25938421	SRKM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418695	25938421	TB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418695	25938421	TB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418695	25938421	TB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418695	25938421	TB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418695	25938421	TS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5935603	29728787	All	2	data and materials cited on the manuscript are freely available for the scientific community	data and materials cited on the manuscript are freely available for the scientific community	-	-	NO
5935603	29728787	All authors	2	read and approved the final manuscript|gave the consent for publication	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5935603	29728787	All authors	2	read and approved the final manuscript|gave the consent for publication	gave the consent for publication	-	-	NO
5935603	29728787	JF	2	participated in all stages of writing the manuscript	participated in all stages of writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5935603	29728787	MH	2	participated in all stages of writing the manuscript	participated in all stages of writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5935603	29728787	PC	2	participated in all stages of writing the manuscript	participated in all stages of writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5935603	29728787	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5827113	29520291	All authors	2	agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved and approved the final version to be published	agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved and approved the final version to be published	-	-	NO
5827113	29520291	BJ	2	performed the experiments, analyzed the data, and interpreted the results|drafted the work|edited and revised the manuscript critically	performed the experiments, analyzed the data, and interpreted the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5827113	29520291	BJ	2	performed the experiments, analyzed the data, and interpreted the results|drafted the work|edited and revised the manuscript critically	drafted the work	Wrote the paper	Writing - Original Draft	YES
5827113	29520291	BJ	2	performed the experiments, analyzed the data, and interpreted the results|drafted the work|edited and revised the manuscript critically	edited and revised the manuscript critically	Wrote the paper	Writing - Review & Editing	YES
5827113	29520291	CC	2	performed the experiments, analyzed the data, and interpreted the results|drafted the work	performed the experiments, analyzed the data, and interpreted the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5827113	29520291	CC	2	performed the experiments, analyzed the data, and interpreted the results|drafted the work	drafted the work	Wrote the paper	Writing - Original Draft	YES
5827113	29520291	MS	2	performed the experiments, analyzed the data, and interpreted the results|drafted the work|edited and revised the manuscript critically	performed the experiments, analyzed the data, and interpreted the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5827113	29520291	MS	2	performed the experiments, analyzed the data, and interpreted the results|drafted the work|edited and revised the manuscript critically	drafted the work	Wrote the paper	Writing - Original Draft	YES
5827113	29520291	MS	2	performed the experiments, analyzed the data, and interpreted the results|drafted the work|edited and revised the manuscript critically	edited and revised the manuscript critically	Wrote the paper	Writing - Review & Editing	YES
5827113	29520291	SC	2	performed the experiments, analyzed the data, and interpreted the results	performed the experiments, analyzed the data, and interpreted the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5827113	29520291	XQ	2	designed the research|performed the experiments, analyzed the data, and interpreted the results|drafted the work	designed the research	Conceived and designed the experiments	Methodology	YES
5827113	29520291	XQ	2	designed the research|performed the experiments, analyzed the data, and interpreted the results|drafted the work	performed the experiments, analyzed the data, and interpreted the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5827113	29520291	XQ	2	designed the research|performed the experiments, analyzed the data, and interpreted the results|drafted the work	drafted the work	Wrote the paper	Writing - Original Draft	YES
5827113	29520291	XS	2	designed the research|performed the experiments, analyzed the data, and interpreted the results|drafted the work|edited and revised the manuscript critically	designed the research	Conceived and designed the experiments	Methodology	YES
5827113	29520291	XS	2	designed the research|performed the experiments, analyzed the data, and interpreted the results|drafted the work|edited and revised the manuscript critically	performed the experiments, analyzed the data, and interpreted the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5827113	29520291	XS	2	designed the research|performed the experiments, analyzed the data, and interpreted the results|drafted the work|edited and revised the manuscript critically	drafted the work	Wrote the paper	Writing - Original Draft	YES
5827113	29520291	XS	2	designed the research|performed the experiments, analyzed the data, and interpreted the results|drafted the work|edited and revised the manuscript critically	edited and revised the manuscript critically	Wrote the paper	Writing - Review & Editing	YES
5827113	29520291	YZ	2	designed the research|edited and revised the manuscript critically	designed the research	Conceived and designed the experiments	Methodology	YES
5827113	29520291	YZ	2	designed the research|edited and revised the manuscript critically	edited and revised the manuscript critically	Wrote the paper	Writing - Review & Editing	YES
6270835	24936711	Dayong Ding	2	the first author, participated in the entire experiment and the work of article writing	the first author, participated in the entire experiment and the work of article writing	Performed the experiments|Wrote the paper	Investigation	YES
6270835	24936711	Jisheng Zhao	2	the second corresponding author, participated in the work of subjects designing	the second corresponding author, participated in the work of subjects designing	Conceived and designed the experiments	-	YES
6270835	24936711	Kai Wang	2	the third author, participated in a partial of the work of vector construction	the third author, participated in a partial of the work of vector construction	Performed the experiments	Investigation	YES
6270835	24936711	Lihong Huang	2	participated in the work of protein purification	participated in the work of protein purification	Performed the experiments	Investigation	YES
6270835	24936711	Shichao Liu	2	the first corresponding author, participated in a partial of the work of technical guidance and the article modification	the first corresponding author, participated in a partial of the work of technical guidance and the article modification	Wrote the paper	Supervision|Writing - Review & Editing	YES
5444057	28533453	K.D.F.	2	undertook the tem study on the beetles and provided the illustrations	undertook the tem study on the beetles and provided the illustrations	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
5444057	28533453	N.W.R.	2	conceived the work and measured the beetle reflection spectra|wrote the initial draft and all authors contributed further editing of the manuscript	conceived the work and measured the beetle reflection spectra	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5444057	28533453	N.W.R.	2	conceived the work and measured the beetle reflection spectra|wrote the initial draft and all authors contributed further editing of the manuscript	wrote the initial draft and all authors contributed further editing of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5444057	28533453	T.M.J.	2	produced the reflectivity data for the fish reflector and developed the theoretical description of the structure	produced the reflectivity data for the fish reflector and developed the theoretical description of the structure	Performed the experiments	Formal analysis|Investigation	YES
5017018	27617097	All authors	2	critically revised the manuscript for important intellectual content	critically revised the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5017018	27617097	TI	2	conceived, planned, and organized the manuscript	conceived, planned, and organized the manuscript	Conceived and designed the experiments	Conceptualization	YES
2000351	17925877	EM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2000351	17925877	EM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2000351	17925877	EM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2000351	17925877	SL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2000351	17925877	SL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2000351	17925877	SL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3980208	24704995	AD	2	histopathological evaluation, manuscript writing and revision	histopathological evaluation, manuscript writing and revision	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
3980208	24704995	BK	2	general concept outlining, manuscript drafting and revision	general concept outlining, manuscript drafting and revision	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
3980208	24704995	DT	2	histopathological evaluation, manuscript drafting	histopathological evaluation, manuscript drafting	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3980208	24704995	MM	2	statistical analysis	statistical analysis	Analyzed the data	Formal analysis	YES
3980208	24704995	SC	2	literature search, photomicrographs acquisition, material preparation	literature search, photomicrographs acquisition, material preparation	-	Formal analysis	YES
3980208	24704995	TH	2	patient clinical information supply, material preparation	patient clinical information supply, material preparation	-	-	NO
3980208	24704995	ZM	2	histopathological evaluation, patient clinical information supply	histopathological evaluation, patient clinical information supply	Performed the experiments	Investigation	YES
4418696	25938522	AC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418696	25938522	AC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418696	25938522	AC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418696	25938522	AC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418696	25938522	AC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418696	25938522	MJO	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418696	25938522	MJO	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418696	25938522	MJO	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418696	25938522	PM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418696	25938522	PM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418696	25938522	PM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5936482	29730843	ADF	2	designed the experimental details|did all the flask and fermentation experiments|interpreted the data|revised the manuscript	designed the experimental details	Conceived and designed the experiments	Methodology	YES
5936482	29730843	ADF	2	designed the experimental details|did all the flask and fermentation experiments|interpreted the data|revised the manuscript	did all the flask and fermentation experiments	Performed the experiments	Investigation	YES
5936482	29730843	ADF	2	designed the experimental details|did all the flask and fermentation experiments|interpreted the data|revised the manuscript	interpreted the data	Analyzed the data	Formal analysis	YES
5936482	29730843	ADF	2	designed the experimental details|did all the flask and fermentation experiments|interpreted the data|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5936482	29730843	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5936482	29730843	Gyuyeon Park	2	during the experiments	during the experiments	-	-	NO
5936482	29730843	HL	2	designed the entire research project|designed the experimental details|designed the experimental details|did all the flask and fermentation experiments|did all the flask and fermentation experiments|interpreted the data|interpreted the data|reviewed the manuscript|revised the manuscript|revised the manuscript	designed the entire research project	Conceived and designed the experiments	Methodology	YES
5936482	29730843	HL	2	designed the entire research project|designed the experimental details|designed the experimental details|did all the flask and fermentation experiments|did all the flask and fermentation experiments|interpreted the data|interpreted the data|reviewed the manuscript|revised the manuscript|revised the manuscript	designed the experimental details	Conceived and designed the experiments	Methodology	YES
5936482	29730843	HL	2	designed the entire research project|designed the experimental details|designed the experimental details|did all the flask and fermentation experiments|did all the flask and fermentation experiments|interpreted the data|interpreted the data|reviewed the manuscript|revised the manuscript|revised the manuscript	designed the experimental details	Conceived and designed the experiments	Methodology	YES
5936482	29730843	HL	2	designed the entire research project|designed the experimental details|designed the experimental details|did all the flask and fermentation experiments|did all the flask and fermentation experiments|interpreted the data|interpreted the data|reviewed the manuscript|revised the manuscript|revised the manuscript	did all the flask and fermentation experiments	Performed the experiments	Investigation	YES
5936482	29730843	HL	2	designed the entire research project|designed the experimental details|designed the experimental details|did all the flask and fermentation experiments|did all the flask and fermentation experiments|interpreted the data|interpreted the data|reviewed the manuscript|revised the manuscript|revised the manuscript	did all the flask and fermentation experiments	Performed the experiments	Investigation	YES
5936482	29730843	HL	2	designed the entire research project|designed the experimental details|designed the experimental details|did all the flask and fermentation experiments|did all the flask and fermentation experiments|interpreted the data|interpreted the data|reviewed the manuscript|revised the manuscript|revised the manuscript	interpreted the data	Analyzed the data	Formal analysis	YES
5936482	29730843	HL	2	designed the entire research project|designed the experimental details|designed the experimental details|did all the flask and fermentation experiments|did all the flask and fermentation experiments|interpreted the data|interpreted the data|reviewed the manuscript|revised the manuscript|revised the manuscript	interpreted the data	Analyzed the data	Formal analysis	YES
5936482	29730843	HL	2	designed the entire research project|designed the experimental details|designed the experimental details|did all the flask and fermentation experiments|did all the flask and fermentation experiments|interpreted the data|interpreted the data|reviewed the manuscript|revised the manuscript|revised the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5936482	29730843	HL	2	designed the entire research project|designed the experimental details|designed the experimental details|did all the flask and fermentation experiments|did all the flask and fermentation experiments|interpreted the data|interpreted the data|reviewed the manuscript|revised the manuscript|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5936482	29730843	HL	2	designed the entire research project|designed the experimental details|designed the experimental details|did all the flask and fermentation experiments|did all the flask and fermentation experiments|interpreted the data|interpreted the data|reviewed the manuscript|revised the manuscript|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5936482	29730843	JA	2	designed the entire research project	designed the entire research project	Conceived and designed the experiments	Methodology	YES
5936482	29730843	KP	2	designed the entire research project	designed the entire research project	Conceived and designed the experiments	Methodology	YES
5936482	29730843	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5936482	29730843	WJ	2	did all the flask and fermentation experiments	did all the flask and fermentation experiments	Performed the experiments	Investigation	YES
5936482	29730843	YECS	2	designed the experimental details|did all the flask and fermentation experiments|interpreted the data|prepared the manuscript|revised the manuscript	designed the experimental details	Conceived and designed the experiments	Methodology	YES
5936482	29730843	YECS	2	designed the experimental details|did all the flask and fermentation experiments|interpreted the data|prepared the manuscript|revised the manuscript	did all the flask and fermentation experiments	Performed the experiments	Investigation	YES
5936482	29730843	YECS	2	designed the experimental details|did all the flask and fermentation experiments|interpreted the data|prepared the manuscript|revised the manuscript	interpreted the data	Analyzed the data	Formal analysis	YES
5936482	29730843	YECS	2	designed the experimental details|did all the flask and fermentation experiments|interpreted the data|prepared the manuscript|revised the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5936482	29730843	YECS	2	designed the experimental details|did all the flask and fermentation experiments|interpreted the data|prepared the manuscript|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
3598080	23381957	AB	2	participated to the study design and interpretation of the data	participated to the study design and interpretation of the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
3598080	23381957	DP	2	contributed to hdad vector production	contributed to hdad vector production	-	-	NO
3598080	23381957	EP	2	performed em studies	performed em studies	Performed the experiments	Investigation	YES
3598080	23381957	FA	2	helped with the pulse and chase experiment	helped with the pulse and chase experiment	Performed the experiments	Investigation	YES
3598080	23381957	FV	2	performed the cloning to make the hdad plasmid	performed the cloning to make the hdad plasmid	Performed the experiments	Investigation	YES
3598080	23381957	JT	2	provided the piz mice and interpreted data relative to monomer-polymer studies	provided the piz mice and interpreted data relative to monomer-polymer studies	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
3598080	23381957	KB	2	performed monomer-polymer analysis	performed monomer-polymer analysis	Performed the experiments	Investigation	YES
3598080	23381957	NBP	2	led and supervised the project through all stages	led and supervised the project through all stages	-	Supervision	YES
3598080	23381957	NP	2	designed and performed all in vitro and in vivo experiments, most of the assays included in the study, and interpreted the data	designed and performed all in vitro and in vivo experiments, most of the assays included in the study, and interpreted the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
3598080	23381957	PM	2	performed immunostainings	performed immunostainings	Performed the experiments	Investigation	YES
3598080	23381957	PN	2	contributed to hdad vector production	contributed to hdad vector production	-	-	NO
3598080	23381957	PP	2	made the hdad vectors	made the hdad vectors	-	-	NO
3598080	23381957	RMS	2	performed part of the plasmid cloning required for in vitro studies	performed part of the plasmid cloning required for in vitro studies	Performed the experiments	Investigation	YES
3598080	23381957	RP	2	performed em studies	performed em studies	Performed the experiments	Investigation	YES
3598080	23381957	SI	2	performed em studies	performed em studies	Performed the experiments	Investigation	YES
5800076	29402215	AA	2	participated in the design, genetic analyses, drafting and coordination of the study	participated in the design, genetic analyses, drafting and coordination of the study	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Project administration|Writing - Original Draft	YES
5800076	29402215	CG	2	performed the initial gene mining analysis and ancestral reconstruction analysis	performed the initial gene mining analysis and ancestral reconstruction analysis	Performed the experiments	Investigation	YES
5800076	29402215	CPH	2	contributed with data and participated in the drafting of the manuscript	contributed with data and participated in the drafting of the manuscript	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Original Draft	YES
5800076	29402215	RB	2	performed the phylogenetic, evolutionary and ancestral state reconstruction analyses and drafted the manuscript	performed the phylogenetic, evolutionary and ancestral state reconstruction analyses and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5800076	29402215	SJO	2	participated in the drafting and coordination of the study	participated in the drafting and coordination of the study	Wrote the paper	Project administration|Writing - Original Draft	YES
5800076	29402215	WEJ	2	participated in the drafting and coordination of the study	participated in the drafting and coordination of the study	Wrote the paper	Project administration|Writing - Original Draft	YES
5827294	29520289	FC	2	performed experiments|wrote the manuscript	performed experiments	Performed the experiments	Investigation	YES
5827294	29520289	FC	2	performed experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5827294	29520289	GD	2	collected data and conducted analysis	collected data and conducted analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5827294	29520289	GL	2	planned and designed the research|wrote the manuscript	planned and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5827294	29520289	GL	2	planned and designed the research|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5827294	29520289	NS	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5827294	29520289	SL	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5827294	29520289	SW	2	planned and designed the research	planned and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5827294	29520289	YH	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5827294	29520289	YL	2	collected data and conducted analysis	collected data and conducted analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270836	25347457	O. Muraoka	2	prepared the manuscript and supervised whole research project	prepared the manuscript and supervised whole research project	Wrote the paper	Supervision|Writing - Original Draft	YES
6270836	25347457	R. Tanaka	2	prepared the manuscript and supervised whole research project	prepared the manuscript and supervised whole research project	Wrote the paper	Supervision|Writing - Original Draft	YES
6270836	25347457	T. Inoue	2	performed the isolation and structure elucidation	performed the isolation and structure elucidation	Performed the experiments	Investigation	YES
6270836	25347457	T. Kikuchi	2	contributed to evaluation of bioactivities	contributed to evaluation of bioactivities	-	-	NO
6270836	25347457	T. Yamada	2	prepared the manuscript and supervised whole research project	prepared the manuscript and supervised whole research project	Wrote the paper	Supervision|Writing - Original Draft	YES
6270836	25347457	Y. Matsui	2	performed the isolation and structure elucidation	performed the isolation and structure elucidation	Performed the experiments	Investigation	YES
3980210	24704997	All authors	2	participated in the revision of the manuscript and have given final approval for the manuscript to be published	participated in the revision of the manuscript and have given final approval for the manuscript to be published	Wrote the paper	Writing - Review & Editing	YES
3980210	24704997	HW	2	study supervision	study supervision	-	Supervision	YES
3980210	24704997	JYC	2	statistical analysis performing	statistical analysis performing	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3980210	24704997	LM	2	statistical analysis performing	statistical analysis performing	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3980210	24704997	SSH	2	laboratory experiments, manuscript drafting	laboratory experiments, manuscript drafting	Wrote the paper	Writing - Original Draft	YES
3980210	24704997	ZWH	2	study concept and design	study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418697	25938508	KK	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418697	25938508	KK	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418697	25938508	KK	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418697	25938508	L-WZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418697	25938508	L-WZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418697	25938508	L-WZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418697	25938508	L-WZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418697	25938508	S-LD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418697	25938508	S-LD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418697	25938508	S-LD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418697	25938508	S-LD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418697	25938508	X-CG	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418697	25938508	X-CG	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418697	25938508	X-CG	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418697	25938508	XCG	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418697	25938508	Y-NZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418697	25938508	Y-NZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418697	25938508	Y-NZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418697	25938508	Y-NZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2000352	17925879	AC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2000352	17925879	BD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2000352	17925879	BD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2000352	17925879	BD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2000352	17925879	BD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2000352	17925879	CL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2000352	17925879	CL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2000352	17925879	CL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2000352	17925879	CL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2000352	17925879	KG	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
2000352	17925879	KG	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2000352	17925879	MA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2000352	17925879	MA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2000352	17925879	MA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2000352	17925879	MA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2000352	17925879	MA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2000352	17925879	MA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2000352	17925879	MA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2000352	17925879	SD	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2000352	17925879	SD	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2000352	17925879	SD	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3598081	23341106	AD	2	provided samples	provided samples	Contributed reagents/materials/analysis tools	Resources	YES
3598081	23341106	BM	2	designed the study and experiments|provided samples|wrote the manuscript	designed the study and experiments	Conceived and designed the experiments	Methodology	YES
3598081	23341106	BM	2	designed the study and experiments|provided samples|wrote the manuscript	provided samples	Contributed reagents/materials/analysis tools	Resources	YES
3598081	23341106	BM	2	designed the study and experiments|provided samples|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3598081	23341106	BV	2	provided samples	provided samples	Contributed reagents/materials/analysis tools	Resources	YES
3598081	23341106	CP	2	designed the study and experiments|edited the paper	designed the study and experiments	Conceived and designed the experiments	Methodology	YES
3598081	23341106	CP	2	designed the study and experiments|edited the paper	edited the paper	Wrote the paper	Writing - Review & Editing	YES
3598081	23341106	DK	2	edited the paper	edited the paper	Wrote the paper	Writing - Review & Editing	YES
3598081	23341106	DM	2	edited the paper	edited the paper	Wrote the paper	Writing - Review & Editing	YES
3598081	23341106	DW	2	designed the study and experiments	designed the study and experiments	Conceived and designed the experiments	Methodology	YES
3598081	23341106	EK	2	analysed data	analysed data	Analyzed the data	Formal analysis	YES
3598081	23341106	FSH	2	analysed data	analysed data	Analyzed the data	Formal analysis	YES
3598081	23341106	HAK	2	designed the study and experiments|provided samples|edited the paper	designed the study and experiments	Conceived and designed the experiments	Methodology	YES
3598081	23341106	HAK	2	designed the study and experiments|provided samples|edited the paper	provided samples	Contributed reagents/materials/analysis tools	Resources	YES
3598081	23341106	HAK	2	designed the study and experiments|provided samples|edited the paper	edited the paper	Wrote the paper	Writing - Review & Editing	YES
3598081	23341106	JB	2	edited the paper	edited the paper	Wrote the paper	Writing - Review & Editing	YES
3598081	23341106	JDH	2	designed the study and experiments	designed the study and experiments	Conceived and designed the experiments	Methodology	YES
3598081	23341106	JF	2	provided samples	provided samples	Contributed reagents/materials/analysis tools	Resources	YES
3598081	23341106	JH	2	designed the study and experiments	designed the study and experiments	Conceived and designed the experiments	Methodology	YES
3598081	23341106	JHS	2	edited the paper	edited the paper	Wrote the paper	Writing - Review & Editing	YES
3598081	23341106	KSF	2	designed the study and experiments	designed the study and experiments	Conceived and designed the experiments	Methodology	YES
3598081	23341106	NMW	2	edited the paper	edited the paper	Wrote the paper	Writing - Review & Editing	YES
3598081	23341106	PE	2	edited the paper	edited the paper	Wrote the paper	Writing - Review & Editing	YES
3598081	23341106	SF	2	edited the paper	edited the paper	Wrote the paper	Writing - Review & Editing	YES
3598081	23341106	StH	2	edited the paper	edited the paper	Wrote the paper	Writing - Review & Editing	YES
3598081	23341106	TW	2	edited the paper	edited the paper	Wrote the paper	Writing - Review & Editing	YES
3598081	23341106	YJP	2	designed the study and experiments	designed the study and experiments	Conceived and designed the experiments	Methodology	YES
5048448	27729984	HI	2	helped draft the manuscript	helped draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5048448	27729984	HK	2	helped draft the manuscript	helped draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5048448	27729984	KH	2	helped draft the manuscript	helped draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5048448	27729984	KM	2	helped draft the manuscript	helped draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5048448	27729984	SM	2	helped draft the manuscript	helped draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5048448	27729984	TN	2	helped draft the manuscript	helped draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5048448	27729984	YI	2	helped draft the manuscript	helped draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5048448	27729984	YK	2	drafted the manuscript, participated in the study design, and performed the statistical analysis	drafted the manuscript, participated in the study design, and performed the statistical analysis	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5936483	29730829	All	PLoS52	co-authors iteratively reviewed the manuscript prior to submission	co-authors iteratively reviewed the manuscript prior to submission	Wrote the paper	Writing - Review & Editing	YES
5936483	29730829	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5936483	29730829	Jeroen Frank	PLoS52	is thanked for setting up bioinformatics pipelines and for useful discussions on 16s rrna gene diversity analysis	is thanked for setting up bioinformatics pipelines and for useful discussions on 16s rrna gene diversity analysis	Performed the experiments	Formal analysis|Methodology	YES
5936483	29730829	KFE	PLoS52	designed the experiments|sampled the peat mosses and performed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5936483	29730829	KFE	PLoS52	designed the experiments|sampled the peat mosses and performed the experiments	sampled the peat mosses and performed the experiments	Performed the experiments	Investigation	YES
5936483	29730829	MAHJvK	PLoS52	analysed the data|co-authors iteratively reviewed the manuscript prior to submission	analysed the data	Analyzed the data	Formal analysis	YES
5936483	29730829	MAHJvK	PLoS52	analysed the data|co-authors iteratively reviewed the manuscript prior to submission	co-authors iteratively reviewed the manuscript prior to submission	Wrote the paper	Writing - Review & Editing	YES
5936483	29730829	MARK	PLoS52	designed the experiments|sampled the peat mosses and performed the experiments|analysed the data|co-authors iteratively reviewed the manuscript prior to submission	designed the experiments	Conceived and designed the experiments	Methodology	YES
5936483	29730829	MARK	PLoS52	designed the experiments|sampled the peat mosses and performed the experiments|analysed the data|co-authors iteratively reviewed the manuscript prior to submission	sampled the peat mosses and performed the experiments	Performed the experiments	Investigation	YES
5936483	29730829	MARK	PLoS52	designed the experiments|sampled the peat mosses and performed the experiments|analysed the data|co-authors iteratively reviewed the manuscript prior to submission	analysed the data	Analyzed the data	Formal analysis	YES
5936483	29730829	MARK	PLoS52	designed the experiments|sampled the peat mosses and performed the experiments|analysed the data|co-authors iteratively reviewed the manuscript prior to submission	co-authors iteratively reviewed the manuscript prior to submission	Wrote the paper	Writing - Review & Editing	YES
5936483	29730829	MSMJ	PLoS52	designed the experiments|co-authors iteratively reviewed the manuscript prior to submission	designed the experiments	Conceived and designed the experiments	Methodology	YES
5936483	29730829	MSMJ	PLoS52	designed the experiments|co-authors iteratively reviewed the manuscript prior to submission	co-authors iteratively reviewed the manuscript prior to submission	Wrote the paper	Writing - Review & Editing	YES
5936483	29730829	Marja Tiirola	PLoS52	is thanked for feedback on the experiments and manuscript	is thanked for feedback on the experiments and manuscript	-	-	NO
5936483	29730829	SLA	PLoS52	designed the experiments|sampled the peat mosses and performed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5936483	29730829	SLA	PLoS52	designed the experiments|sampled the peat mosses and performed the experiments	sampled the peat mosses and performed the experiments	Performed the experiments	Investigation	YES
5936483	29730829	TP	PLoS52	sampled the peat mosses and performed the experiments	sampled the peat mosses and performed the experiments	Performed the experiments	Investigation	YES
5936483	29730829	The authors	PLoS52	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5801776	29409445	AS	2	participated in the whole genome dna methylation experiments, data analysis, and drafting the manuscript	participated in the whole genome dna methylation experiments, data analysis, and drafting the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5801776	29409445	DLT	2	participated in the conception of the study and editing of the manuscript	participated in the conception of the study and editing of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5801776	29409445	EC	2	participated in the whole genome dna methylation experiments, data analysis, and drafting the manuscript	participated in the whole genome dna methylation experiments, data analysis, and drafting the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5801776	29409445	FP	2	performed whole-genome integrative analysis and participated in drafting the manuscript	performed whole-genome integrative analysis and participated in drafting the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5801776	29409445	HK	2	conceived the study and participated in the design of experiments and drafting of the manuscript	conceived the study and participated in the design of experiments and drafting of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Writing - Original Draft	YES
5801776	29409445	HN	2	carried out the experiments, participated in data analysis, and drafted the manuscript	carried out the experiments, participated in data analysis, and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5801776	29409445	JLW	2	participated in the whole genome dna methylation experiments, data analysis, and drafting the manuscript	participated in the whole genome dna methylation experiments, data analysis, and drafting the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5801776	29409445	MDC	2	participated in the whole genome dna methylation experiments, data analysis, and drafting the manuscript	participated in the whole genome dna methylation experiments, data analysis, and drafting the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5801776	29409445	PAM	2	participated in the whole genome dna methylation experiments, data analysis, and drafting the manuscript	participated in the whole genome dna methylation experiments, data analysis, and drafting the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6270837	25036151	PET	2	inhibition in spinach chloroplasts of the compounds, writing of the paper	inhibition in spinach chloroplasts of the compounds, writing of the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6270837	25036151	SAR	2	writing of the paper	writing of the paper	Wrote the paper	Writing - Original Draft	YES
5827301	29520283	All authors	2	listed have made a substantial, direct and intellectual contribution to the work, and approved it for publication	listed have made a substantial, direct and intellectual contribution to the work, and approved it for publication	-	-	NO
5468688	28584171	A.W.	2	to draft the case study section	to draft the case study section	Wrote the paper	Writing - Original Draft	YES
5468688	28584171	B.B.	2	led the kenya case study and drafted the case study section	led the kenya case study and drafted the case study section	Wrote the paper	Writing - Original Draft	YES
5468688	28584171	E.L.	2	to draft the ghana case study section	to draft the ghana case study section	Wrote the paper	Writing - Original Draft	YES
5468688	28584171	J.K.	2	collected data for the zambia case study	collected data for the zambia case study	Performed the experiments	Investigation	YES
5468688	28584171	K.A.-M.	2	to draft the ghana case study section|led in environmental data collection	to draft the ghana case study section	Wrote the paper	Writing - Original Draft	YES
5468688	28584171	K.A.-M.	2	to draft the ghana case study section|led in environmental data collection	led in environmental data collection	Performed the experiments	Investigation	YES
5468688	28584171	K.S.	2	collected data for the zambia case study	collected data for the zambia case study	Performed the experiments	Investigation	YES
5468688	28584171	L.M.	2	who also played a key role in data collection	who also played a key role in data collection	Performed the experiments	Investigation	YES
5468688	28584171	M.L.	2	authored the introduction, discussion and concluding sections	authored the introduction, discussion and concluding sections	Wrote the paper	Writing - Original Draft	YES
5468688	28584171	M.S.	2	of environmental data for the kenya case study	of environmental data for the kenya case study	-	-	NO
5468688	28584171	N.A.	2	to draft the zambia case study	to draft the zambia case study	Wrote the paper	Writing - Original Draft	YES
2000353	17925876	JE	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2000353	17925876	JE	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2000353	17925876	JE	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2000353	17925876	JN	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2000353	17925876	JN	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2000353	17925876	MK	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
2000353	17925876	MK	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2000353	17925876	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2000353	17925876	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
2000353	17925876	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4651703	26618177	Nobuyasu Komasawa	2	were involved in the study design, study implementation, data analysis, and paper preparation	were involved in the study design, study implementation, data analysis, and paper preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
4651703	26618177	Ryosuke Mihara	2	were involved in the study design, study implementation, data analysis, and paper preparation	were involved in the study design, study implementation, data analysis, and paper preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
4651703	26618177	Sayuri Matsunami	2	were involved in the study design, study implementation, data analysis, and paper preparation	were involved in the study design, study implementation, data analysis, and paper preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
4651703	26618177	Toshiaki Minami	2	was involved in the study design and paper preparation	was involved in the study design and paper preparation	Conceived and designed the experiments	Methodology	YES
4418698	25938456	JW	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418698	25938456	LD	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4418698	25938456	LD	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4418698	25938456	LD	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418698	25938456	XQ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418698	25938456	XQ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4418698	25938456	XQ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4418698	25938456	XQ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418698	25938456	ZP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418698	25938456	ZP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418698	25938456	ZP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418698	25938456	ZP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418698	25938456	ZQ	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4418698	25938456	ZQ	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5943200	29744607	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5943200	29744607	HL	2	designed experiments and wrote the manuscript	designed experiments and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5943200	29744607	HW	2	carried out the agarose gel electrophoresis experiments and analyzed the data	carried out the agarose gel electrophoresis experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5943200	29744607	KC	2	designed experiments and wrote the manuscript|designed the primers|performed the pcr experiments	designed experiments and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5943200	29744607	KC	2	designed experiments and wrote the manuscript|designed the primers|performed the pcr experiments	designed the primers	Conceived and designed the experiments	-	YES
5943200	29744607	KC	2	designed experiments and wrote the manuscript|designed the primers|performed the pcr experiments	performed the pcr experiments	Performed the experiments	Investigation	YES
5943200	29744607	LN	2	carried out the agarose gel electrophoresis experiments and analyzed the data	carried out the agarose gel electrophoresis experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5943200	29744607	QW	2	performed the pcr experiments	performed the pcr experiments	Performed the experiments	Investigation	YES
5943200	29744607	SW	2	carried out the agarose gel electrophoresis experiments and analyzed the data	carried out the agarose gel electrophoresis experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5943200	29744607	XS	2	performed the pcr experiments	performed the pcr experiments	Performed the experiments	Investigation	YES
5803842	29415650	AK	2	helped in sample harvest as well as performed trns analysis for storage root crop species authentification	helped in sample harvest as well as performed trns analysis for storage root crop species authentification	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5803842	29415650	AKB	2	conceived the idea, designed the methods and helped write the paper	conceived the idea, designed the methods and helped write the paper	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
5803842	29415650	DH	2	conceived the idea, designed the methods and helped write the paper	conceived the idea, designed the methods and helped write the paper	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
5803842	29415650	KRK	2	designed and performed experiments, implemented the genomics search, and helped write the manuscript	designed and performed experiments, implemented the genomics search, and helped write the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5052799	27721980	AK	2	conceived and designed the study, participated in the data collection and drafted the manuscript|has full access to all the study data and takes responsibility for data integrity and accuracy of data analysis	conceived and designed the study, participated in the data collection and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Writing - Original Draft	YES
5052799	27721980	AK	2	conceived and designed the study, participated in the data collection and drafted the manuscript|has full access to all the study data and takes responsibility for data integrity and accuracy of data analysis	has full access to all the study data and takes responsibility for data integrity and accuracy of data analysis	Analyzed the data	Data curation|Formal analysis	YES
5052799	27721980	MB	2	participated in the data collection and contributed to drafting the manuscript	participated in the data collection and contributed to drafting the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5052799	27721980	TF	2	provided the statistical analysis and contributed to drafting the manuscript	provided the statistical analysis and contributed to drafting the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3980213	24705000	AGG	2	data analysis, manuscript drafting	data analysis, manuscript drafting	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3980213	24705000	CG	2	data aquisition, manuscript drafting	data aquisition, manuscript drafting	Wrote the paper	Writing - Original Draft	YES
3980213	24705000	CM	2	data aquisition, manuscript drafting	data aquisition, manuscript drafting	Wrote the paper	Writing - Original Draft	YES
3980213	24705000	DC	2	study conception and design, data interpretation, manuscript drafting	study conception and design, data interpretation, manuscript drafting	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
3980213	24705000	EF	2	study design contribution and critical revision for important intellectual content	study design contribution and critical revision for important intellectual content	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
3980213	24705000	GP	2	study design contribution and critical revision for important intellectual content	study design contribution and critical revision for important intellectual content	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
6270838	25264829	All authors	2	wrote this paper and have given approval to the final version of the manuscript	wrote this paper and have given approval to the final version of the manuscript	Wrote the paper	Writing - Original Draft	YES
6270838	25264829	FH	2	participated scientific discussions	participated scientific discussions	-	-	NO
6270838	25264829	LW	2	performed chemical synthesis|performed biochemical assay	performed chemical synthesis	Performed the experiments	Investigation	YES
6270838	25264829	LW	2	performed chemical synthesis|performed biochemical assay	performed biochemical assay	Performed the experiments	Investigation	YES
6270838	25264829	MRS	2	performed biochemical assay	performed biochemical assay	Performed the experiments	Investigation	YES
6270838	25264829	MV	2	co-directed this work	co-directed this work	-	Supervision	YES
6270838	25264829	NGE	2	performed biochemical assay	performed biochemical assay	Performed the experiments	Investigation	YES
6270838	25264829	SB	2	performed chemical synthesis	performed chemical synthesis	Performed the experiments	Investigation	YES
6270838	25264829	WQL	2	co-directed this work|performed chemical synthesis	co-directed this work	-	Supervision	YES
6270838	25264829	WQL	2	co-directed this work|performed chemical synthesis	performed chemical synthesis	Performed the experiments	Investigation	YES
3598082	23364955	BS	2	performed experiments that included analyses of lymhocytes	performed experiments that included analyses of lymhocytes	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3598082	23364955	DBS	2	performed experiments that included analyses of lymhocytes	performed experiments that included analyses of lymhocytes	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3598082	23364955	DS	2	performed experiments that included analyses of lymhocytes	performed experiments that included analyses of lymhocytes	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3598082	23364955	EB	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
3598082	23364955	LG	2	designed experiments, analysed data and wrote the paper	designed experiments, analysed data and wrote the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3598082	23364955	PS	2	designed and performed experiments, analysed data and wrote the paper	designed and performed experiments, analysed data and wrote the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5827413	29520287	All authors	2	listed have made a substantial, direct and intellectual contribution to the work and approved it for publication	listed have made a substantial, direct and intellectual contribution to the work and approved it for publication	-	-	NO
3980214	24705001	DA	2	experiment concept and design|experiment performing|data analysis|manuscript writing	experiment concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
3980214	24705001	DA	2	experiment concept and design|experiment performing|data analysis|manuscript writing	experiment performing	Performed the experiments	Investigation	YES
3980214	24705001	DA	2	experiment concept and design|experiment performing|data analysis|manuscript writing	data analysis	Analyzed the data	Formal analysis	YES
3980214	24705001	DA	2	experiment concept and design|experiment performing|data analysis|manuscript writing	manuscript writing	Wrote the paper	Writing - Original Draft	YES
3980214	24705001	GT	2	experiment concept and design|data analysis|contributed to reagents/materials/analysis tools|manuscript writing	experiment concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
3980214	24705001	GT	2	experiment concept and design|data analysis|contributed to reagents/materials/analysis tools|manuscript writing	data analysis	Analyzed the data	Formal analysis	YES
3980214	24705001	GT	2	experiment concept and design|data analysis|contributed to reagents/materials/analysis tools|manuscript writing	contributed to reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
3980214	24705001	GT	2	experiment concept and design|data analysis|contributed to reagents/materials/analysis tools|manuscript writing	manuscript writing	Wrote the paper	Writing - Original Draft	YES
3980214	24705001	MB	2	experiment performing	experiment performing	Performed the experiments	Investigation	YES
3980214	24705001	MDS	2	experiment concept and design|experiment performing|data analysis|manuscript writing	experiment concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
3980214	24705001	MDS	2	experiment concept and design|experiment performing|data analysis|manuscript writing	experiment performing	Performed the experiments	Investigation	YES
3980214	24705001	MDS	2	experiment concept and design|experiment performing|data analysis|manuscript writing	data analysis	Analyzed the data	Formal analysis	YES
3980214	24705001	MDS	2	experiment concept and design|experiment performing|data analysis|manuscript writing	manuscript writing	Wrote the paper	Writing - Original Draft	YES
3980214	24705001	MF	2	experiment performing	experiment performing	Performed the experiments	Investigation	YES
3980214	24705001	SMD	2	contributed to reagents/materials/analysis tools|manuscript writing	contributed to reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
3980214	24705001	SMD	2	contributed to reagents/materials/analysis tools|manuscript writing	manuscript writing	Wrote the paper	Writing - Original Draft	YES
3980214	24705001	VM	2	experiment performing	experiment performing	Performed the experiments	Investigation	YES
2000354	17925868	HW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2000354	17925868	HW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2000354	17925868	HW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2000354	17925868	HW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2000354	17925868	JN	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
2000354	17925868	JN	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
2000354	17925868	JN	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2000354	17925868	MM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
2000354	17925868	NM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2000354	17925868	NM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2000354	17925868	NM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2000354	17925868	PK	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
2000354	17925868	PK	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2000354	17925868	PS	PLoS5	Conceived and designed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2000354	17925868	PS	PLoS5	Conceived and designed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
2000354	17925868	PS	PLoS5	Conceived and designed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
2000354	17925868	PS	PLoS5	Conceived and designed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5943202	29744605	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5943202	29744605	LZ	2	provided instruction on the experimental design and helped with article revisions	provided instruction on the experimental design and helped with article revisions	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Review & Editing	YES
5943202	29744605	TM	2	worked on project design and article revisions	worked on project design and article revisions	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5943202	29744605	XL	2	helped complete the paperwork	helped complete the paperwork	-	-	NO
5943202	29744605	XZ	2	under the	under the	-	-	NO
5943202	29744605	ZC	2	directed xz under the	directed xz under the	-	Supervision	YES
5468689	28584172	all other authors	2	joint contribution, and listed alphabetically	joint contribution, and listed alphabetically	-	-	NO
5804041	29415651	AMF	2	performed data analysis	performed data analysis	Analyzed the data	Formal analysis	YES
5804041	29415651	ASMC	2	participated in the experimental design and rna sequencing|performed data analysis	participated in the experimental design and rna sequencing	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5804041	29415651	ASMC	2	participated in the experimental design and rna sequencing|performed data analysis	performed data analysis	Analyzed the data	Formal analysis	YES
5804041	29415651	GBO	2	participated in the experimental design and rna sequencing|performed data analysis|drafted the manuscript	participated in the experimental design and rna sequencing	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5804041	29415651	GBO	2	participated in the experimental design and rna sequencing|performed data analysis|drafted the manuscript	performed data analysis	Analyzed the data	Formal analysis	YES
5804041	29415651	GBO	2	participated in the experimental design and rna sequencing|performed data analysis|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5804041	29415651	JEK	2	performed data analysis	performed data analysis	Analyzed the data	Formal analysis	YES
5804041	29415651	JMR	2	provided the experimental environment and coordination	provided the experimental environment and coordination	-	Project administration	YES
5804041	29415651	LCAR	2	provided the experimental environment and coordination	provided the experimental environment and coordination	-	Project administration	YES
5804041	29415651	LLC	2	provided the experimental environment and coordination	provided the experimental environment and coordination	-	Project administration	YES
5804041	29415651	MDP	2	participated in the experimental design and rna sequencing	participated in the experimental design and rna sequencing	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4418699	25938406	BK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418699	25938406	BK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418699	25938406	BK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418699	25938406	BK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418699	25938406	GN	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418699	25938406	GN	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418699	25938406	MD	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418699	25938406	MD	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418699	25938406	MM	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418699	25938406	MM	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418699	25938406	OL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418699	25938406	OL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418699	25938406	OL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418699	25938406	WO	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418699	25938406	WO	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270839	25438082	All authors	2	discussed the results and commented on the manuscript	discussed the results and commented on the manuscript	-	-	NO
6270839	25438082	B.Z.	2	conceived the the project	conceived the the project	Conceived and designed the experiments	Conceptualization	YES
6270839	25438082	D.W.	2	performed the biological assays	performed the biological assays	Performed the experiments	Investigation	YES
6270839	25438082	H.Y.	2	performed the biological assays	performed the biological assays	Performed the experiments	Investigation	YES
6270839	25438082	M.L.	2	designed the experiments and executed the chemical synthesis	designed the experiments and executed the chemical synthesis	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6270839	25438082	M.Z.	2	designed the experiments and executed the chemical synthesis|performed the biological assays	designed the experiments and executed the chemical synthesis	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6270839	25438082	M.Z.	2	designed the experiments and executed the chemical synthesis|performed the biological assays	performed the biological assays	Performed the experiments	Investigation	YES
6270839	25438082	W.S.	2	conceived the the project	conceived the the project	Conceived and designed the experiments	Conceptualization	YES
6270839	25438082	X.H.	2	conceived the the project	conceived the the project	Conceived and designed the experiments	Conceptualization	YES
5057477	27777780	HN	2	helped with the data analysis	helped with the data analysis	Analyzed the data	Formal analysis	YES
5057477	27777780	HY	2	designed the study protocols, acquired the data, performed the statistical analysis, and completed the manuscript for publication	designed the study protocols, acquired the data, performed the statistical analysis, and completed the manuscript for publication	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5057477	27777780	KO	2	helped with the data analysis	helped with the data analysis	Analyzed the data	Formal analysis	YES
5057477	27777780	MD	2	supervised the interpretation of the results and writing of the reports	supervised the interpretation of the results and writing of the reports	Analyzed the data|Wrote the paper	Formal analysis|Supervision	YES
5057477	27777780	MY	2	supervised the interpretation of the results and writing of the reports	supervised the interpretation of the results and writing of the reports	Analyzed the data|Wrote the paper	Formal analysis|Supervision	YES
5057477	27777780	RI	2	supervised the interpretation of the results and writing of the reports	supervised the interpretation of the results and writing of the reports	Analyzed the data|Wrote the paper	Formal analysis|Supervision	YES
5057477	27777780	SH	2	supervised the interpretation of the results and writing of the reports	supervised the interpretation of the results and writing of the reports	Analyzed the data|Wrote the paper	Formal analysis|Supervision	YES
5057477	27777780	TT	2	revised the manuscript and approved it for publication	revised the manuscript and approved it for publication	Wrote the paper	Writing - Review & Editing	YES
5827417	29520288	C-TH	2	provided scientific criticisms and manuscript proofreading	provided scientific criticisms and manuscript proofreading	-	-	NO
5827417	29520288	JY	2	helped with the database designing and manuscript writing	helped with the database designing and manuscript writing	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Software|Writing - Original Draft	YES
5827417	29520288	LZ	2	performed the data collection and analysis, developed the database, and wrote the manuscript	performed the data collection and analysis, developed the database, and wrote the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Software|Writing - Original Draft	YES
5827417	29520288	ML	2	helped with the database designing and manuscript writing	helped with the database designing and manuscript writing	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Software|Writing - Original Draft	YES
5827417	29520288	SB	2	provided scientific criticisms and manuscript proofreading	provided scientific criticisms and manuscript proofreading	-	-	NO
5827417	29520288	SZ	2	performed the data collection and analysis, developed the database, and wrote the manuscript|supervised the whole project and helped with the manuscript writing	performed the data collection and analysis, developed the database, and wrote the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Software|Writing - Original Draft	YES
5827417	29520288	SZ	2	performed the data collection and analysis, developed the database, and wrote the manuscript|supervised the whole project and helped with the manuscript writing	supervised the whole project and helped with the manuscript writing	Wrote the paper	Supervision|Writing - Original Draft	YES
5827417	29520288	XW	2	supervised the whole project and helped with the manuscript writing	supervised the whole project and helped with the manuscript writing	Wrote the paper	Supervision|Writing - Original Draft	YES
5827417	29520288	YW	2	performed the data collection and analysis, developed the database, and wrote the manuscript	performed the data collection and analysis, developed the database, and wrote the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Software|Writing - Original Draft	YES
5827417	29520288	ZX	2	provided scientific criticisms and manuscript proofreading	provided scientific criticisms and manuscript proofreading	-	-	NO
3598083	23401241	DA	2	contributed with reagents and to discussions and reviewed/edited the manuscript	contributed with reagents and to discussions and reviewed/edited the manuscript	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Review & Editing	YES
3598083	23401241	DL	2	contributed with reagents and to discussions and reviewed/edited the manuscript	contributed with reagents and to discussions and reviewed/edited the manuscript	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Review & Editing	YES
3598083	23401241	FC	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
3598083	23401241	GP	2	contributed with reagents and to discussions and reviewed/edited the manuscript	contributed with reagents and to discussions and reviewed/edited the manuscript	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Review & Editing	YES
3598083	23401241	IA	2	analysed data	analysed data	Analyzed the data	Formal analysis	YES
3598083	23401241	LF	2	analysed data|wrote the final version of the manuscript	analysed data	Analyzed the data	Formal analysis	YES
3598083	23401241	LF	2	analysed data|wrote the final version of the manuscript	wrote the final version of the manuscript	Wrote the paper	Writing - Original Draft	YES
3598083	23401241	LG	2	analysed data|contributed with reagents and to discussions and reviewed/edited the manuscript	analysed data	Analyzed the data	Formal analysis	YES
3598083	23401241	LG	2	analysed data|contributed with reagents and to discussions and reviewed/edited the manuscript	contributed with reagents and to discussions and reviewed/edited the manuscript	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Review & Editing	YES
3598083	23401241	MC	2	analysed data	analysed data	Analyzed the data	Formal analysis	YES
3598083	23401241	MDO	2	analysed data	analysed data	Analyzed the data	Formal analysis	YES
3598083	23401241	MF	2	conceived the study|analysed data|wrote the final version of the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
3598083	23401241	MF	2	conceived the study|analysed data|wrote the final version of the manuscript	analysed data	Analyzed the data	Formal analysis	YES
3598083	23401241	MF	2	conceived the study|analysed data|wrote the final version of the manuscript	wrote the final version of the manuscript	Wrote the paper	Writing - Original Draft	YES
3598083	23401241	PP	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
3598083	23401241	RK	2	contributed with reagents and to discussions and reviewed/edited the manuscript	contributed with reagents and to discussions and reviewed/edited the manuscript	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Review & Editing	YES
3598083	23401241	RL	2	contributed with reagents and to discussions and reviewed/edited the manuscript	contributed with reagents and to discussions and reviewed/edited the manuscript	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Review & Editing	YES
3598083	23401241	RM	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
3598083	23401241	VC	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
3598083	23401241	VM	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
2000355	17925878	JH	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2000355	17925878	MA	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
2000355	17925878	MA	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2000355	17925878	MK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
2000355	17925878	MK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2000355	17925878	MT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2000355	17925878	MT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2000355	17925878	MT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2000355	17925878	MT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2000355	17925878	MT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2000355	17925878	SK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2000355	17925878	SK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2000355	17925878	SK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2000355	17925878	SY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2000355	17925878	SY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2000355	17925878	SY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2000355	17925878	SY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2000355	17925878	SY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2000355	17925878	TK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2000355	17925878	TK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2000355	17925878	TK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2000355	17925878	TK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2000355	17925878	TK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2000355	17925878	YI	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
2000355	17925878	YI	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2000355	17925878	YK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2000355	17925878	YK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2000355	17925878	YK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2000355	17925878	YK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2000355	17925878	YK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418700	25938227	C-CH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418700	25938227	C-CH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418700	25938227	C-CH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418700	25938227	H-YS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418700	25938227	H-YS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418700	25938227	H-YS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418700	25938227	P-RH	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418700	25938227	P-RH	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418700	25938227	P-RH	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418700	25938227	P-RH	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418700	25938227	S-CC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418700	25938227	S-CC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418700	25938227	S-CC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418700	25938227	S-YC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418700	25938227	S-YC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4418700	25938227	S-YC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418700	25938227	W-CL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418700	25938227	Y-CS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5957016	29774473	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5957016	29774473	H-JK	PLoS52	wrote the paper|designed the research|obtained funding	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5957016	29774473	H-JK	PLoS52	wrote the paper|designed the research|obtained funding	designed the research	Conceived and designed the experiments	Methodology	YES
5957016	29774473	H-JK	PLoS52	wrote the paper|designed the research|obtained funding	obtained funding	-	Funding acquisition	YES
5957016	29774473	IK	PLoS52	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5957016	29774473	J-HK	PLoS52	wrote the paper|designed the research|obtained funding	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5957016	29774473	J-HK	PLoS52	wrote the paper|designed the research|obtained funding	designed the research	Conceived and designed the experiments	Methodology	YES
5957016	29774473	J-HK	PLoS52	wrote the paper|designed the research|obtained funding	obtained funding	-	Funding acquisition	YES
5957016	29774473	S-JP	PLoS52	obtained funding	obtained funding	-	Funding acquisition	YES
5957016	29774473	S-MH	PLoS52	carried out the experiments|wrote the paper|designed the research	carried out the experiments	Performed the experiments	Investigation	YES
5957016	29774473	S-MH	PLoS52	carried out the experiments|wrote the paper|designed the research	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5957016	29774473	S-MH	PLoS52	carried out the experiments|wrote the paper|designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
5957016	29774473	W-JS	PLoS52	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5468690	28584173	All authors	2	contributed to writing the manuscript	contributed to writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5468690	28584173	D.W.R.	2	developed the overall study design assisted by all other authors	developed the overall study design assisted by all other authors	Conceived and designed the experiments	Methodology	YES
5468690	28584173	K.E.J.	2	developed the overall study design assisted by all other authors|contributed to writing the manuscript	developed the overall study design assisted by all other authors	Conceived and designed the experiments	Methodology	YES
5468690	28584173	K.E.J.	2	developed the overall study design assisted by all other authors|contributed to writing the manuscript	contributed to writing the manuscript	Wrote the paper	Writing - Original Draft	YES
6270840	25170949	Alicja Kuban-Jankowska	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
6270840	25170949	Magdalena Gorska	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6270840	25170949	Magdalena Gorska	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
6270840	25170949	Magdalena Gorska	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
6270840	25170949	Magdalena Gorska	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270840	25170949	Michal Aleksander Zmijewski	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
6270840	25170949	Michal Szkatula	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
6270840	25170949	Michal Wozniak	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6270840	25170949	Michal Wozniak	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
6270840	25170949	Monika Gorzynik	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5827528	29520285	AP	7	Conceived and designed the experiments, performed the measurements|Discussed the results	Conceived and designed the experiments, performed the measurements	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
5827528	29520285	AP	7	Conceived and designed the experiments, performed the measurements|Discussed the results	Discussed the results	-	-	NO
5827528	29520285	EN	7	Conceived and designed the experiments, performed the measurements|Analyzed the data and wrote the manuscript|Discussed the results	Conceived and designed the experiments, performed the measurements	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
5827528	29520285	EN	7	Conceived and designed the experiments, performed the measurements|Analyzed the data and wrote the manuscript|Discussed the results	Analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5827528	29520285	EN	7	Conceived and designed the experiments, performed the measurements|Analyzed the data and wrote the manuscript|Discussed the results	Discussed the results	-	-	NO
5827528	29520285	ZN	7	Conceived and designed the experiments, performed the measurements	Conceived and designed the experiments, performed the measurements	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
5804050	29415652	G. All	2	authors have revised the manuscript and agree to publish it	authors have revised the manuscript and agree to publish it	Wrote the paper	Writing - Review & Editing	YES
3598084	23495141	CL	PLoS52	designed the experiments|analyzed the data|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
3598084	23495141	CL	PLoS52	designed the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
3598084	23495141	CL	PLoS52	designed the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3598084	23495141	CR	PLoS52	provided reagents	provided reagents	Contributed reagents/materials/analysis tools	Resources	YES
3598084	23495141	FVH	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
3598084	23495141	IPe	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
3598084	23495141	IPi	PLoS52	designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
3598084	23495141	IPi	PLoS52	designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
3598084	23495141	IPi	PLoS52	designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
3598084	23495141	IPi	PLoS52	designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3598084	23495141	LD	PLoS52	designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
3598084	23495141	LD	PLoS52	designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
3598084	23495141	LD	PLoS52	designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
3598084	23495141	LD	PLoS52	designed the experiments|performed the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3598084	23495141	LP	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
3598084	23495141	LP	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
3598084	23495141	MB	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
3598084	23495141	MV	PLoS52	designed the experiments|analyzed the data|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
3598084	23495141	MV	PLoS52	designed the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
3598084	23495141	MV	PLoS52	designed the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3598084	23495141	SV	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
3598084	23495141	TM	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
3910074	24516360	Faruk Toktas	2	are co-first authors for equal contribution for the present study	are co-first authors for equal contribution for the present study	-	-	NO
3910074	24516360	Senol Yavuz	2	are co-first authors for equal contribution for the present study	are co-first authors for equal contribution for the present study	-	-	NO
6270841	25255248	AM	2	performed the research and analyzed the data	performed the research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270841	25255248	DWM	2	designed the research and wrote the paper	designed the research and wrote the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
6270841	25255248	JCW	2	designed the research and wrote the paper	designed the research and wrote the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
6270841	25255248	LB	2	performed the research and analyzed the data	performed the research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5468691	28584174	D.G.	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5468691	28584174	F.W.	2	helped develop the system dynamics model and ran scenarios	helped develop the system dynamics model and ran scenarios	Performed the experiments	Investigation|Methodology	YES
5468691	28584174	J.L.	2	collected field data and helped draft the manuscript	collected field data and helped draft the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5468691	28584174	K.M.R.	2	designed the model and helped draft the manuscript	designed the model and helped draft the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5468691	28584174	T.R.	2	helped design the study	helped design the study	Conceived and designed the experiments	Methodology	YES
4655022	26634203	Sheng-Mou Hsiao	2	contributed equally to this work	contributed equally to this work	-	-	NO
4655022	26634203	Ting-Chen Chang	2	contributed equally to this work	contributed equally to this work	-	-	NO
4083317	24998917	CZ	2	immunohistochemical staining	immunohistochemical staining	Performed the experiments	Investigation	YES
4083317	24998917	LZ	2	immunohistochemical staining	immunohistochemical staining	Performed the experiments	Investigation	YES
4083317	24998917	XH	2	samples collection and statistical analysis	samples collection and statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4083317	24998917	YS	2	manuscript design and writing	manuscript design and writing	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
2000357	17925867	AF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2000357	17925867	AF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2000357	17925867	AF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2000357	17925867	AF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2000357	17925867	AF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418701	25938437	ALN	PLoS5	Contributed reagents/materials/analysis tools|Critically revised the manuscript for important intellectual content	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418701	25938437	ALN	PLoS5	Contributed reagents/materials/analysis tools|Critically revised the manuscript for important intellectual content	Critically revised the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4418701	25938437	BG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418701	25938437	FC	PLoS5	Computation	Computation	-	Formal analysis	YES
4418701	25938437	HL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418701	25938437	HL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418701	25938437	HL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418701	25938437	KM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418701	25938437	PSS	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418701	25938437	TK	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4418701	25938437	TK	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418701	25938437	XS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418701	25938437	YY	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4418701	25938437	YY	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418701	25938437	ZJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Computation	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418701	25938437	ZJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Computation	Analyzed the data	Analyzed the data	Formal analysis	YES
4418701	25938437	ZJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Computation	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418701	25938437	ZJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Computation	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418701	25938437	ZJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Computation	Computation	-	Formal analysis	YES
5827667	29520290	DF	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5827667	29520290	IV	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5827667	29520290	LSa	PLoS52	designed and created the plantsize computer application	designed and created the plantsize computer application	Conceived and designed the experiments|Performed the experiments	Formal analysis|Investigation	YES
5827667	29520290	LSz	PLoS52	designed the experiments, evaluated the data and wrote the manuscript	designed the experiments, evaluated the data and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5827667	29520290	NA	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5080705	27800163	AK	2	conceived of and designed the study|participated in the data acquisition|conducted the data analysis|prepared the first draft of the manuscript, and all authors revised the draft critically and approved the final manuscript for publication	conceived of and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5080705	27800163	AK	2	conceived of and designed the study|participated in the data acquisition|conducted the data analysis|prepared the first draft of the manuscript, and all authors revised the draft critically and approved the final manuscript for publication	participated in the data acquisition	Performed the experiments	Investigation	YES
5080705	27800163	AK	2	conceived of and designed the study|participated in the data acquisition|conducted the data analysis|prepared the first draft of the manuscript, and all authors revised the draft critically and approved the final manuscript for publication	conducted the data analysis	Analyzed the data	Formal analysis	YES
5080705	27800163	AK	2	conceived of and designed the study|participated in the data acquisition|conducted the data analysis|prepared the first draft of the manuscript, and all authors revised the draft critically and approved the final manuscript for publication	prepared the first draft of the manuscript, and all authors revised the draft critically and approved the final manuscript for publication	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5080705	27800163	All authors	2	contributed to the interpretation of the analysis results	contributed to the interpretation of the analysis results	Analyzed the data	Formal analysis	YES
5080705	27800163	CT	2	conceived of and designed the study|conducted the data analysis	conceived of and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5080705	27800163	CT	2	conceived of and designed the study|conducted the data analysis	conducted the data analysis	Analyzed the data	Formal analysis	YES
5080705	27800163	EM	2	conducted the data analysis	conducted the data analysis	Analyzed the data	Formal analysis	YES
5080705	27800163	LG	2	conducted the data analysis	conducted the data analysis	Analyzed the data	Formal analysis	YES
5080705	27800163	RD	2	conceived of and designed the study|participated in the data acquisition|conducted the data analysis|prepared the first draft of the manuscript, and all authors revised the draft critically and approved the final manuscript for publication	conceived of and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5080705	27800163	RD	2	conceived of and designed the study|participated in the data acquisition|conducted the data analysis|prepared the first draft of the manuscript, and all authors revised the draft critically and approved the final manuscript for publication	participated in the data acquisition	Performed the experiments	Investigation	YES
5080705	27800163	RD	2	conceived of and designed the study|participated in the data acquisition|conducted the data analysis|prepared the first draft of the manuscript, and all authors revised the draft critically and approved the final manuscript for publication	conducted the data analysis	Analyzed the data	Formal analysis	YES
5080705	27800163	RD	2	conceived of and designed the study|participated in the data acquisition|conducted the data analysis|prepared the first draft of the manuscript, and all authors revised the draft critically and approved the final manuscript for publication	prepared the first draft of the manuscript, and all authors revised the draft critically and approved the final manuscript for publication	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5959823	29777449	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5959823	29777449	CJ	PLoS52	performed the experiments|made manuscript revisions	performed the experiments	Performed the experiments	Investigation	YES
5959823	29777449	CJ	PLoS52	performed the experiments|made manuscript revisions	made manuscript revisions	Wrote the paper	Writing - Review & Editing	YES
5959823	29777449	DS	PLoS52	provided help in the experimental design and data analysis|made manuscript revisions	provided help in the experimental design and data analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Methodology|Resources	YES
5959823	29777449	DS	PLoS52	provided help in the experimental design and data analysis|made manuscript revisions	made manuscript revisions	Wrote the paper	Writing - Review & Editing	YES
5959823	29777449	HZ	PLoS52	conceived and supervised the study|designed experiments and analyzed the data|performed the experiments	conceived and supervised the study	Conceived and designed the experiments	Conceptualization|Supervision	YES
5959823	29777449	HZ	PLoS52	conceived and supervised the study|designed experiments and analyzed the data|performed the experiments	designed experiments and analyzed the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5959823	29777449	HZ	PLoS52	conceived and supervised the study|designed experiments and analyzed the data|performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5959823	29777449	JS	PLoS52	conceived and supervised the study|designed experiments and analyzed the data	conceived and supervised the study	Conceived and designed the experiments	Conceptualization|Supervision	YES
5959823	29777449	JS	PLoS52	conceived and supervised the study|designed experiments and analyzed the data	designed experiments and analyzed the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5959823	29777449	LL	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5959823	29777449	Life Sciences	PLoS52	northwestern polytechnical university for providing all instruments used in the study	northwestern polytechnical university for providing all instruments used in the study	-	-	NO
5959823	29777449	QH	PLoS52	provided help in the experimental design and data analysis	provided help in the experimental design and data analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Methodology|Resources	YES
5959823	29777449	SL	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5959823	29777449	The authors	PLoS52	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5959823	29777449	XX	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5959823	29777449	YZ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5806312	29422035	XZ	2	performed the data analyses|critically revised the manuscript	performed the data analyses	Analyzed the data	Formal analysis	YES
5806312	29422035	XZ	2	performed the data analyses|critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5806312	29422035	YZ	2	designed this study|performed the data analyses|drafted the manuscript	designed this study	Conceived and designed the experiments	Methodology	YES
5806312	29422035	YZ	2	designed this study|performed the data analyses|drafted the manuscript	performed the data analyses	Analyzed the data	Formal analysis	YES
5806312	29422035	YZ	2	designed this study|performed the data analyses|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5806312	29422035	ZMC	2	designed this study|critically revised the manuscript	designed this study	Conceived and designed the experiments	Methodology	YES
5806312	29422035	ZMC	2	designed this study|critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5806312	29422035	ZY	2	critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
3598085	23417922	AOG	2	acquired data	acquired data	Performed the experiments	Investigation	YES
3598085	23417922	AZ	2	designed the study, analyzed data, and provided funding	designed the study, analyzed data, and provided funding	Conceived and designed the experiments|Analyzed the data	Formal analysis|Funding acquisition|Methodology	YES
3598085	23417922	CDG	2	provided clinical samples	provided clinical samples	Contributed reagents/materials/analysis tools	Resources	YES
3598085	23417922	CW	2	designed the study, provided funding and wrote the manuscript	designed the study, provided funding and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Funding acquisition|Methodology|Writing - Original Draft	YES
3598085	23417922	DL	2	acquired data	acquired data	Performed the experiments	Investigation	YES
3598085	23417922	DP	2	acquired data	acquired data	Performed the experiments	Investigation	YES
3598085	23417922	EL	2	provided intellectual input	provided intellectual input	-	-	NO
3598085	23417922	HH	2	acquired data	acquired data	Performed the experiments	Investigation	YES
3598085	23417922	KK	2	acquired data	acquired data	Performed the experiments	Investigation	YES
3598085	23417922	MD	2	designed the study, performed experiments, analysed data, provided funding, and wrote the paper	designed the study, performed experiments, analysed data, provided funding, and wrote the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Funding acquisition|Investigation|Methodology|Writing - Original Draft	YES
3598085	23417922	MH	2	acquired data	acquired data	Performed the experiments	Investigation	YES
3598085	23417922	MM	2	acquired data	acquired data	Performed the experiments	Investigation	YES
3598085	23417922	OS	2	designed the study, performed experiments, analysed data, provided funding, and wrote the paper	designed the study, performed experiments, analysed data, provided funding, and wrote the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Funding acquisition|Investigation|Methodology|Writing - Original Draft	YES
3598085	23417922	RRK	2	provided intellectual input	provided intellectual input	-	-	NO
3598085	23417922	SV	2	acquired data	acquired data	Performed the experiments	Investigation	YES
3598085	23417922	YD	2	acquired data	acquired data	Performed the experiments	Investigation	YES
5468692	28584175	A.A.C.	2	conceived the idea for the article	conceived the idea for the article	Conceived and designed the experiments	Conceptualization	YES
5468692	28584175	All authors	2	contributed equally to the writing of the manuscript	contributed equally to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
4418702	25938667	AL	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4418702	25938667	AL	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418702	25938667	ALR	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4418702	25938667	ALR	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418702	25938667	AV	PLoS5	Contributed reagents/materials/analysis tools|City	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418702	25938667	AV	PLoS5	Contributed reagents/materials/analysis tools|City	City	-	-	NO
4418702	25938667	CM	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418702	25938667	CX	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418702	25938667	CX	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418702	25938667	CX	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418702	25938667	EG	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418702	25938667	EGH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418702	25938667	EGH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418702	25938667	EGH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418702	25938667	EGH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418702	25938667	ER	PLoS5	Contributed reagents/materials/analysis tools|Hermosillo, sonora hospital	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418702	25938667	ER	PLoS5	Contributed reagents/materials/analysis tools|Hermosillo, sonora hospital	Hermosillo, sonora hospital	-	-	NO
4418702	25938667	FJE	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418702	25938667	FJE	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418702	25938667	JG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418702	25938667	JG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418702	25938667	JG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418702	25938667	LR	PLoS5	Contributed reagents/materials/analysis tools|City	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418702	25938667	LR	PLoS5	Contributed reagents/materials/analysis tools|City	City	-	-	NO
4418702	25938667	MET	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4418702	25938667	MET	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418702	25938667	MNR	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418702	25938667	OPR	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4418702	25938667	OPR	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418702	25938667	OV	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418702	25938667	OV	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418702	25938667	PM	PLoS5	Contributed reagents/materials/analysis tools|City	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418702	25938667	PM	PLoS5	Contributed reagents/materials/analysis tools|City	City	-	-	NO
4418702	25938667	UM	PLoS5	Contributed reagents/materials/analysis tools|Hermosillo, sonora hospital	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418702	25938667	UM	PLoS5	Contributed reagents/materials/analysis tools|Hermosillo, sonora hospital	Hermosillo, sonora hospital	-	-	NO
6270842	25375337	Anthi Tapeinou	2	have contributed to the design, synthesis and analysis of linear and cyclic peptide analogues	have contributed to the design, synthesis and analysis of linear and cyclic peptide analogues	Conceived and designed the experiments|Performed the experiments	Investigation	YES
6270842	25375337	Dimitrios Gatos	2	have contributed to the design, synthesis and analysis of linear and cyclic peptide analogues	have contributed to the design, synthesis and analysis of linear and cyclic peptide analogues	Conceived and designed the experiments|Performed the experiments	Investigation	YES
6270842	25375337	Ioannis Kanistras	2	have contributed to the in vivo biological evaluation of synthesized analogues	have contributed to the in vivo biological evaluation of synthesized analogues	Performed the experiments	Investigation	YES
6270842	25375337	John Matsoukas	2	have contributed to the design, synthesis and analysis of linear and cyclic peptide analogues	have contributed to the design, synthesis and analysis of linear and cyclic peptide analogues	Conceived and designed the experiments|Performed the experiments	Investigation	YES
6270842	25375337	Mihalis Aggelidakis	2	have contributed to the design, synthesis and analysis of linear and cyclic peptide analogues	have contributed to the design, synthesis and analysis of linear and cyclic peptide analogues	Conceived and designed the experiments|Performed the experiments	Investigation	YES
6270842	25375337	Theodore Tselios	2	have contributed to the design, synthesis and analysis of linear and cyclic peptide analogues	have contributed to the design, synthesis and analysis of linear and cyclic peptide analogues	Conceived and designed the experiments|Performed the experiments	Investigation	YES
6270842	25375337	Vivian Tseveleki	2	have contributed to the in vivo biological evaluation of synthesized analogues	have contributed to the in vivo biological evaluation of synthesized analogues	Performed the experiments	Investigation	YES
4083319	24998919	BM	2	image analysis, manuscript drafting	image analysis, manuscript drafting	Analyzed the data|Wrote the paper	Visualization|Writing - Original Draft	YES
4083319	24998919	BP	2	experiment co-manager, myosin and immunohistochemistry studies specialist, manuscript drafting	experiment co-manager, myosin and immunohistochemistry studies specialist, manuscript drafting	Performed the experiments|Wrote the paper	Investigation|Project administration|Writing - Original Draft	YES
4083319	24998919	ICM	2	experiment co-manager, manuscript drafting	experiment co-manager, manuscript drafting	Wrote the paper	Project administration|Writing - Original Draft	YES
4083319	24998919	MK	2	analytical immunohistochemistry experiments, data interpretation, manuscript drafting	analytical immunohistochemistry experiments, data interpretation, manuscript drafting	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5468693	28584176	A.L.	2	were involved in acquisition of previously published data that were presented in the article	were involved in acquisition of previously published data that were presented in the article	Performed the experiments	Investigation	YES
5468693	28584176	All authors	2	contributed to the conception of the study, drafting of the article and critically revising it for intellectual content|have given final approval of the version submitted	contributed to the conception of the study, drafting of the article and critically revising it for intellectual content	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
5468693	28584176	All authors	2	contributed to the conception of the study, drafting of the article and critically revising it for intellectual content|have given final approval of the version submitted	have given final approval of the version submitted	-	-	NO
5468693	28584176	B.T.M.	2	were involved in acquisition of previously published data that were presented in the article	were involved in acquisition of previously published data that were presented in the article	Performed the experiments	Investigation	YES
5468693	28584176	J.A.C.	2	were involved in acquisition of previously published data that were presented in the article	were involved in acquisition of previously published data that were presented in the article	Performed the experiments	Investigation	YES
5468693	28584176	J.E.B.H.	2	were involved in acquisition of previously published data that were presented in the article	were involved in acquisition of previously published data that were presented in the article	Performed the experiments	Investigation	YES
5468693	28584176	J.S.	2	were involved in acquisition of previously published data that were presented in the article	were involved in acquisition of previously published data that were presented in the article	Performed the experiments	Investigation	YES
5468693	28584176	K.H.	2	were involved in acquisition of previously published data that were presented in the article	were involved in acquisition of previously published data that were presented in the article	Performed the experiments	Investigation	YES
5468693	28584176	K.J.A.	2	were involved in acquisition of previously published data that were presented in the article	were involved in acquisition of previously published data that were presented in the article	Performed the experiments	Investigation	YES
5468693	28584176	L.W.	2	were involved in acquisition of previously published data that were presented in the article	were involved in acquisition of previously published data that were presented in the article	Performed the experiments	Investigation	YES
5468693	28584176	M.P.R.	2	were involved in acquisition of previously published data that were presented in the article	were involved in acquisition of previously published data that were presented in the article	Performed the experiments	Investigation	YES
5468693	28584176	R.R.K.	2	were involved in acquisition of previously published data that were presented in the article	were involved in acquisition of previously published data that were presented in the article	Performed the experiments	Investigation	YES
5468693	28584176	S.C.	2	were involved in acquisition of previously published data that were presented in the article	were involved in acquisition of previously published data that were presented in the article	Performed the experiments	Investigation	YES
5084398	27800164	AKL	2	the jseptic clinical trial group helped in critically revising the manuscript	the jseptic clinical trial group helped in critically revising the manuscript	Wrote the paper	Writing - Review & Editing	YES
5084398	27800164	HY	2	the jseptic clinical trial group helped in critically revising the manuscript	the jseptic clinical trial group helped in critically revising the manuscript	Wrote the paper	Writing - Review & Editing	YES
5084398	27800164	MS	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5084398	27800164	NS	2	the jseptic clinical trial group helped in critically revising the manuscript	the jseptic clinical trial group helped in critically revising the manuscript	Wrote the paper	Writing - Review & Editing	YES
5084398	27800164	ST	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
2001179	17940608	DG	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2001179	17940608	DG	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2001179	17940608	ES	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2001179	17940608	JF	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2001179	17940608	MD	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2001179	17940608	MD	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2001179	17940608	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2001179	17940608	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
2001179	17940608	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2001179	17940608	RK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2001179	17940608	RK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2001179	17940608	RK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2001179	17940608	RK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2001179	17940608	RL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
2001179	17940608	RL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2001179	17940608	RR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2001179	17940608	RR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2001179	17940608	RR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2001179	17940608	SC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2001179	17940608	SC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
2001179	17940608	SC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5806438	29422031	CG	2	performed animal husbandry, tissue processing, probe preparation, and in situ hybridization, confocal microscopy, and contributed to writing the manuscript	performed animal husbandry, tissue processing, probe preparation, and in situ hybridization, confocal microscopy, and contributed to writing the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5806438	29422031	DLS	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5962521	29785487	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5962521	29785487	CYH	PLoS52	conceived and designed the experiments|drafted the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5962521	29785487	CYH	PLoS52	conceived and designed the experiments|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5962521	29785487	WZ	PLoS52	performed the study	performed the study	Performed the experiments	Investigation	YES
5962521	29785487	XQH	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5962521	29785487	YG	PLoS52	performed the study	performed the study	Performed the experiments	Investigation	YES
5829059	29527220	All authors	2	reviewed and approved this submission	reviewed and approved this submission	-	-	NO
5829059	29527220	PL	2	analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5829059	29527220	YX	2	analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5829059	29527220	YZ	2	analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6270843	24647032	E.K.A.A.	2	conceived the study and participated in its design, results and discussion, and coordination	conceived the study and participated in its design, results and discussion, and coordination	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
6270843	24647032	M.A.A.	2	conceived the study and participated in its design, results and discussion, and coordination	conceived the study and participated in its design, results and discussion, and coordination	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
6270843	24647032	R.R.A.	2	carried out the biological assay	carried out the biological assay	Performed the experiments	Investigation	YES
3628097	23554171	All authors	2	discussed the results and commented on the manuscript	discussed the results and commented on the manuscript	-	-	NO
3628097	23554171	DN	2	designed the experiments|performed most of experiments and analysed the data|supervised the project|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
3628097	23554171	DN	2	designed the experiments|performed most of experiments and analysed the data|supervised the project|wrote the manuscript	performed most of experiments and analysed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3628097	23554171	DN	2	designed the experiments|performed most of experiments and analysed the data|supervised the project|wrote the manuscript	supervised the project	-	Supervision	YES
3628097	23554171	DN	2	designed the experiments|performed most of experiments and analysed the data|supervised the project|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3628097	23554171	FT	2	designed the experiments|performed most of experiments and analysed the data	designed the experiments	Conceived and designed the experiments	Methodology	YES
3628097	23554171	FT	2	designed the experiments|performed most of experiments and analysed the data	performed most of experiments and analysed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3628097	23554171	NM	2	developed the inducible knockdown lentivirus system and produced lentiviruses	developed the inducible knockdown lentivirus system and produced lentiviruses	Performed the experiments	Investigation|Methodology	YES
3628097	23554171	SM	2	developed the inducible knockdown lentivirus system and produced lentiviruses	developed the inducible knockdown lentivirus system and produced lentiviruses	Performed the experiments	Investigation|Methodology	YES
3628097	23554171	YB	2	designed the experiments|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
3628097	23554171	YB	2	designed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4418703	25938491	AKI	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418703	25938491	AKI	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418703	25938491	AKI	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418703	25938491	GG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418703	25938491	GG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418703	25938491	GG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418703	25938491	GG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418703	25938491	GGI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418703	25938491	GGI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418703	25938491	GGI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418703	25938491	GGI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418703	25938491	MFKM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418703	25938491	SL	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4418703	25938491	SL	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418703	25938491	TF	PLoS5	Contributed reagents/materials/analysis tools|Revised the manuscript critically for important intellectual content	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418703	25938491	TF	PLoS5	Contributed reagents/materials/analysis tools|Revised the manuscript critically for important intellectual content	Revised the manuscript critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4418703	25938491	WL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418703	25938491	XL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5097421	27826449	BF	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5097421	27826449	MC	2	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5097421	27826449	PFL	2	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5097421	27826449	PV	2	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5807776	29426285	BG	2	analyzed animal records	analyzed animal records	Analyzed the data	Formal analysis	YES
5807776	29426285	FB	2	conceived the study|performed experiments, analyses, and wrote the paper	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5807776	29426285	FB	2	conceived the study|performed experiments, analyses, and wrote the paper	performed experiments, analyses, and wrote the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5807776	29426285	JE	2	supervised the heifer development program, and artificially inseminated the heifers	supervised the heifer development program, and artificially inseminated the heifers	-	Software|Supervision	YES
5807776	29426285	LK-A	2	received, curated and maintained animal records	received, curated and maintained animal records	Analyzed the data	Data curation	YES
5807776	29426285	ME	2	received, curated and maintained animal records	received, curated and maintained animal records	Analyzed the data	Data curation	YES
5807776	29426285	PD	2	conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5807776	29426285	SD	2	performed experiments, analyses, and wrote the paper	performed experiments, analyses, and wrote the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5807776	29426285	SR	2	conceived the study|supervised the heifer development program, and artificially inseminated the heifers	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5807776	29426285	SR	2	conceived the study|supervised the heifer development program, and artificially inseminated the heifers	supervised the heifer development program, and artificially inseminated the heifers	-	Software|Supervision	YES
2001180	17940597	AM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
2001180	17940597	AM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2001180	17940597	EA	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2001180	17940597	HB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
2001180	17940597	JZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
2001180	17940597	LD	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5962522	29785587	AMN	2	performed and analyzed the flow cytometry experiments	performed and analyzed the flow cytometry experiments	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5962522	29785587	All	2	data generated or analysed during this study are included in this published article and its additional files	data generated or analysed during this study are included in this published article and its additional files	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5962522	29785587	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5962522	29785587	DPP	2	carried out the experimental studies and drafted the manuscript	carried out the experimental studies and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5962522	29785587	FATG	2	participated in the design of the study and helped to draft the manuscript	participated in the design of the study and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5962522	29785587	LMPM	2	conceived the study, participated in its design and coordination	conceived the study, participated in its design and coordination	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
5962522	29785587	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5962522	29785587	VCR	2	participated in the design of the study and helped to draft the manuscript	participated in the design of the study and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
6270844	25375331	Helen M. Wallace	PLoS52	contributed reagents, materials or analysis tools|wrote the manuscript	contributed reagents, materials or analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
6270844	25375331	Helen M. Wallace	PLoS52	contributed reagents, materials or analysis tools|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6270844	25375331	Mohammad Katouli	PLoS52	contributed reagents, materials or analysis tools|wrote the manuscript	contributed reagents, materials or analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
6270844	25375331	Mohammad Katouli	PLoS52	contributed reagents, materials or analysis tools|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6270844	25375331	Motahareh Nobakht	PLoS52	conceived and designed the experiments|performed the experiments|analysed the data|wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6270844	25375331	Motahareh Nobakht	PLoS52	conceived and designed the experiments|performed the experiments|analysed the data|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
6270844	25375331	Motahareh Nobakht	PLoS52	conceived and designed the experiments|performed the experiments|analysed the data|wrote the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
6270844	25375331	Motahareh Nobakht	PLoS52	conceived and designed the experiments|performed the experiments|analysed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6270844	25375331	Peter R. Brooks	PLoS52	conceived and designed the experiments|analysed the data|contributed reagents, materials or analysis tools|wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6270844	25375331	Peter R. Brooks	PLoS52	conceived and designed the experiments|analysed the data|contributed reagents, materials or analysis tools|wrote the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
6270844	25375331	Peter R. Brooks	PLoS52	conceived and designed the experiments|analysed the data|contributed reagents, materials or analysis tools|wrote the manuscript	contributed reagents, materials or analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
6270844	25375331	Peter R. Brooks	PLoS52	conceived and designed the experiments|analysed the data|contributed reagents, materials or analysis tools|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6270844	25375331	Ronald J. Quinn	PLoS52	analysed the data|wrote the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
6270844	25375331	Ronald J. Quinn	PLoS52	analysed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6270844	25375331	Stephen J. Trueman	PLoS52	contributed reagents, materials or analysis tools|wrote the manuscript	contributed reagents, materials or analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
6270844	25375331	Stephen J. Trueman	PLoS52	contributed reagents, materials or analysis tools|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6270844	25375331	Tanja Grkovic	PLoS52	performed the experiments|analysed the data|contributed reagents, materials or analysis tools|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
6270844	25375331	Tanja Grkovic	PLoS52	performed the experiments|analysed the data|contributed reagents, materials or analysis tools|wrote the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
6270844	25375331	Tanja Grkovic	PLoS52	performed the experiments|analysed the data|contributed reagents, materials or analysis tools|wrote the manuscript	contributed reagents, materials or analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
6270844	25375331	Tanja Grkovic	PLoS52	performed the experiments|analysed the data|contributed reagents, materials or analysis tools|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5829449	29527219	RB	2	performed the experimental work|drafted the manuscript, and all authors read and revised the manuscript	performed the experimental work	Performed the experiments	Investigation	YES
5829449	29527219	RB	2	performed the experimental work|drafted the manuscript, and all authors read and revised the manuscript	drafted the manuscript, and all authors read and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5829449	29527219	RD	2	conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5829449	29527219	RP	2	conceived the study|supervised the experiments	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5829449	29527219	RP	2	conceived the study|supervised the experiments	supervised the experiments	-	Supervision	YES
5829449	29527219	SI	2	performed the experimental work	performed the experimental work	Performed the experiments	Investigation	YES
5829449	29527219	SL	2	conceived the study|supervised the experiments	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5829449	29527219	SL	2	conceived the study|supervised the experiments	supervised the experiments	-	Supervision	YES
4418704	25938417	AH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418704	25938417	FG	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418704	25938417	FG	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418704	25938417	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418704	25938417	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418704	25938417	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418704	25938417	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418704	25938417	KF	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418704	25938417	KM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418704	25938417	KM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418704	25938417	KM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418704	25938417	NB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418704	25938417	NB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418704	25938417	NB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5468695	28584178	Both authors	2	contributed to the ideas presented, edited drafts of the paper and approved the submitted version	contributed to the ideas presented, edited drafts of the paper and approved the submitted version	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
5807830	29426290	AZK	1	Conceived and designed the study|Wrote the manuscript	Conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5807830	29426290	AZK	1	Conceived and designed the study|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5807830	29426290	LJH	1	Conceived and designed the study|Wrote the manuscript	Conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5807830	29426290	LJH	1	Conceived and designed the study|Wrote the manuscript	Wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5100216	27833752	EC	2	participated as a local investigator, participated in the design of the study, and helped to draft the manuscript	participated as a local investigator, participated in the design of the study, and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5100216	27833752	ES	2	participated as a local investigator and helped to draft the manuscript	participated as a local investigator and helped to draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5100216	27833752	NR	2	participated in the design of the study and performed the statistical analysis	participated in the design of the study and performed the statistical analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5100216	27833752	PP	2	conceived the study, participated in its design as well as coordination, and drafted the manuscript	conceived the study, participated in its design as well as coordination, and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
5100216	27833752	SP	2	conceived the study, participated in its design as well as coordination, and drafted the manuscript	conceived the study, participated in its design as well as coordination, and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
4083323	24998923	all authors	2	gave substantial contributions to the conception and design of the work and to the acquisition, analysis, and interpretation of data	gave substantial contributions to the conception and design of the work and to the acquisition, analysis, and interpretation of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Investigation|Resources	YES
6460952	31015952	All authors	2	have given approval to the final version of the manuscript	have given approval to the final version of the manuscript	-	-	NO
2001181	17940601	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Revised the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2001181	17940601	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Revised the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
2001181	17940601	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Revised the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
2001181	17940601	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Revised the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2001181	17940601	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Revised the manuscript	Revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
2001181	17940601	JT	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Revised the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2001181	17940601	JT	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Revised the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2001181	17940601	JT	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Revised the manuscript	Revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
2001181	17940601	SG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Revised the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2001181	17940601	SG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Revised the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2001181	17940601	SG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Revised the manuscript	Revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
2001181	17940601	TS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2001181	17940601	TS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2001181	17940601	TS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2001181	17940601	TS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2001181	17940601	TS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3628099	23436775	AMM	2	designed experiments and interpreted data|wrote the manuscript|carried out the data analysis	designed experiments and interpreted data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
3628099	23436775	AMM	2	designed experiments and interpreted data|wrote the manuscript|carried out the data analysis	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3628099	23436775	AMM	2	designed experiments and interpreted data|wrote the manuscript|carried out the data analysis	carried out the data analysis	Analyzed the data	Formal analysis	YES
3628099	23436775	BP	2	carried out in vitro cell experiments|were involved with in vivo experiments on mouse models	carried out in vitro cell experiments	Performed the experiments	Investigation	YES
3628099	23436775	BP	2	carried out in vitro cell experiments|were involved with in vivo experiments on mouse models	were involved with in vivo experiments on mouse models	Performed the experiments	Investigation|Methodology	YES
3628099	23436775	CC	2	carried out in vitro cell experiments	carried out in vitro cell experiments	Performed the experiments	Investigation	YES
3628099	23436775	CK	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3628099	23436775	CWVK	2	was involved in peptide design and synthesis	was involved in peptide design and synthesis	Conceived and designed the experiments|Performed the experiments	Investigation	YES
3628099	23436775	DLG	2	were involved in xenograft experiments	were involved in xenograft experiments	-	-	NO
3628099	23436775	HLG	2	designed experiments and interpreted data|carried out in vitro cell experiments|were involved with in vivo experiments on mouse models|wrote the manuscript|carried out the data analysis	designed experiments and interpreted data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
3628099	23436775	HLG	2	designed experiments and interpreted data|carried out in vitro cell experiments|were involved with in vivo experiments on mouse models|wrote the manuscript|carried out the data analysis	carried out in vitro cell experiments	Performed the experiments	Investigation	YES
3628099	23436775	HLG	2	designed experiments and interpreted data|carried out in vitro cell experiments|were involved with in vivo experiments on mouse models|wrote the manuscript|carried out the data analysis	were involved with in vivo experiments on mouse models	Performed the experiments	Investigation|Methodology	YES
3628099	23436775	HLG	2	designed experiments and interpreted data|carried out in vitro cell experiments|were involved with in vivo experiments on mouse models|wrote the manuscript|carried out the data analysis	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3628099	23436775	HLG	2	designed experiments and interpreted data|carried out in vitro cell experiments|were involved with in vivo experiments on mouse models|wrote the manuscript|carried out the data analysis	carried out the data analysis	Analyzed the data	Formal analysis	YES
3628099	23436775	JHN	2	were involved with in vivo experiments on mouse models	were involved with in vivo experiments on mouse models	Performed the experiments	Investigation|Methodology	YES
3628099	23436775	JM	2	assist in gli1 in vitro experiments	assist in gli1 in vitro experiments	Performed the experiments	Investigation	YES
3628099	23436775	KS	2	were involved in vivo transgenic mouse models	were involved in vivo transgenic mouse models	Performed the experiments	Investigation|Methodology	YES
3628099	23436775	LDS	2	were involved in xenograft experiments	were involved in xenograft experiments	-	-	NO
3628099	23436775	LMS	2	were involved in vivo transgenic mouse models	were involved in vivo transgenic mouse models	Performed the experiments	Investigation|Methodology	YES
3628099	23436775	PK	2	were involved in vivo transgenic mouse models	were involved in vivo transgenic mouse models	Performed the experiments	Investigation|Methodology	YES
3628099	23436775	RT	2	were involved in vivo transgenic mouse models	were involved in vivo transgenic mouse models	Performed the experiments	Investigation|Methodology	YES
5962525	29785517	AEA	2	designed the study, evaluated the results and revised the manuscript	designed the study, evaluated the results and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5962525	29785517	All	2	data are presented in the main paper	data are presented in the main paper	-	-	NO
5962525	29785517	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5962525	29785517	MAA	2	designed the study, evaluated the results and revised the manuscript	designed the study, evaluated the results and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5962525	29785517	RAH	2	designed the study, collected the data, analysed and interpreted the data, and wrote the manuscript	designed the study, collected the data, analysed and interpreted the data, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5962525	29785517	RS	2	analysed and interpreted the data, and wrote the manuscript	analysed and interpreted the data, and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5962525	29785517	TME	2	designed the study, evaluated the results and revised the manuscript	designed the study, evaluated the results and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5962525	29785517	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5829517	29527213	All authors	2	read and approved the manuscript	read and approved the manuscript	-	-	NO
6270845	24699151	Hao Zhang	2	participated in compounds synthesis	participated in compounds synthesis	Performed the experiments	Investigation	YES
6270845	24699151	John E. Casida	2	contributed a lot to manuscript revision	contributed a lot to manuscript revision	Wrote the paper	Writing - Review & Editing	YES
6270845	24699151	Kechang Liu	2	participated in compounds synthesis	participated in compounds synthesis	Performed the experiments	Investigation	YES
6270845	24699151	Lei Guo	2	assisted in insecticidal activity tests	assisted in insecticidal activity tests	-	-	NO
6270845	24699151	Pei Liang	2	assisted in insecticidal activity tests	assisted in insecticidal activity tests	-	-	NO
6270845	24699151	Ruiquan Liu	2	participated in compounds synthesis	participated in compounds synthesis	Performed the experiments	Investigation	YES
6270845	24699151	Shangzhong Liu	2	designed the theme of the study and carried out the most of compounds synthesis as well as manuscript preparation	designed the theme of the study and carried out the most of compounds synthesis as well as manuscript preparation	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
6270845	24699151	Yi Wang	2	designed the theme of the study and carried out the most of compounds synthesis as well as manuscript preparation	designed the theme of the study and carried out the most of compounds synthesis as well as manuscript preparation	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
4418705	25938683	GNW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418705	25938683	GNW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418705	25938683	GNW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418705	25938683	JLZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418705	25938683	JLZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418705	25938683	JLZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418705	25938683	WJL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418705	25938683	WY	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418705	25938683	XLG	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418705	25938683	YS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418705	25938683	YS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418705	25938683	YWY	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5809864	29433432	BS	2	conceived ideas and designed the analysis pipeline|analyzed and interpreted the data|wrote the manuscript	conceived ideas and designed the analysis pipeline	Conceived and designed the experiments	Conceptualization	YES
5809864	29433432	BS	2	conceived ideas and designed the analysis pipeline|analyzed and interpreted the data|wrote the manuscript	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5809864	29433432	BS	2	conceived ideas and designed the analysis pipeline|analyzed and interpreted the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5809864	29433432	FW	2	analyzed and interpreted the data|wrote the manuscript	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5809864	29433432	FW	2	analyzed and interpreted the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5809864	29433432	JY	2	analyzed and interpreted the data	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5809864	29433432	YL	2	analyzed and interpreted the data	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5809864	29433432	ZD	2	analyzed and interpreted the data	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5109763	27891229	AU	2	provided guidance on the structure and content of the manuscript	provided guidance on the structure and content of the manuscript	-	Supervision	YES
5109763	27891229	HM	2	provided guidance on the structure and content of the manuscript	provided guidance on the structure and content of the manuscript	-	Supervision	YES
5109763	27891229	MD	2	provided guidance on the structure and content of the manuscript	provided guidance on the structure and content of the manuscript	-	Supervision	YES
5109763	27891229	MK	2	developed the concept, search strategy, and data extraction for this review	developed the concept, search strategy, and data extraction for this review	Conceived and designed the experiments|Analyzed the data	Conceptualization|Data curation	YES
4083324	24998924	All authors	2	contributed to this work and approved the final version of the paper	contributed to this work and approved the final version of the paper	-	-	NO
4083324	24998924	CF	2	work writing, culture cells and immunofluorescence technique|microfluidic devices fabrication	work writing, culture cells and immunofluorescence technique	Performed the experiments|Wrote the paper	Investigation	YES
4083324	24998924	CF	2	work writing, culture cells and immunofluorescence technique|microfluidic devices fabrication	microfluidic devices fabrication	-	-	NO
4083324	24998924	DG	2	manuscript writing and editing, work coordinating	manuscript writing and editing, work coordinating	Wrote the paper	Project administration|Writing - Original Draft|Writing - Review & Editing	YES
4083324	24998924	GA	2	contribution to immunofluorescence development and execution	contribution to immunofluorescence development and execution	Performed the experiments	Investigation	YES
4083324	24998924	IF	2	microfluidic devices fabrication	microfluidic devices fabrication	-	-	NO
4083324	24998924	LP	2	contribution to immunofluorescence development and execution	contribution to immunofluorescence development and execution	Performed the experiments	Investigation	YES
4083324	24998924	RDC	2	manuscript writing and editing, work coordinating	manuscript writing and editing, work coordinating	Wrote the paper	Project administration|Writing - Original Draft|Writing - Review & Editing	YES
5124227	27933169	JC	2	conceptualized, designed, and drafted the manuscript for important intellectual content	conceptualized, designed, and drafted the manuscript for important intellectual content	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4655043	26634210	Minzhong Tang	2	contributed equally to this study	contributed equally to this study	-	-	NO
4655043	26634210	Ningjiang Ou	2	contributed equally to this study	contributed equally to this study	-	-	NO
4418706	25938438	DS	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418706	25938438	DS	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418706	25938438	JH	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418706	25938438	JH	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418706	25938438	JS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418706	25938438	JS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418706	25938438	JS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418706	25938438	JZ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4418706	25938438	JZ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4418706	25938438	JZ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418706	25938438	LT	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4418706	25938438	LT	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4418706	25938438	LT	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418706	25938438	YD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418706	25938438	YD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418706	25938438	YD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418706	25938438	YD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5468697	28584180	J.C.S.	2	assisted with the interviews and writing of the paper	assisted with the interviews and writing of the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5468697	28584180	K.L.B.	2	conducted the interviews, analysed the data and drafted the article	conducted the interviews, analysed the data and drafted the article	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4083325	24998925	LB	2	experiments performing|manuscript design and writing	experiments performing	Performed the experiments	Investigation	YES
4083325	24998925	LB	2	experiments performing|manuscript design and writing	manuscript design and writing	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
4083325	24998925	QL	2	experiments performing	experiments performing	Performed the experiments	Investigation	YES
4083325	24998925	QW	2	experiments conceiving and design|manuscript design and writing	experiments conceiving and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4083325	24998925	QW	2	experiments conceiving and design|manuscript design and writing	manuscript design and writing	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
4083325	24998925	XS	2	experiments performing	experiments performing	Performed the experiments	Investigation	YES
4083325	24998925	YH	2	data analysis	data analysis	Analyzed the data	Formal analysis	YES
4083325	24998925	YL	2	data analysis	data analysis	Analyzed the data	Formal analysis	YES
5829544	29527214	C-MR	PLoS52	designed the study|contributed to scientific discussions that guided the project|wrote the paper	designed the study	Conceived and designed the experiments	Methodology	YES
5829544	29527214	C-MR	PLoS52	designed the study|contributed to scientific discussions that guided the project|wrote the paper	contributed to scientific discussions that guided the project	-	Supervision	YES
5829544	29527214	C-MR	PLoS52	designed the study|contributed to scientific discussions that guided the project|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5829544	29527214	HK	PLoS52	performed all the experiments|wrote the paper	performed all the experiments	Performed the experiments	Investigation	YES
5829544	29527214	HK	PLoS52	performed all the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5829544	29527214	TK	PLoS52	performed all the experiments|helped with the in vitro experiments and in vivo treatments	performed all the experiments	Performed the experiments	Investigation	YES
5829544	29527214	TK	PLoS52	performed all the experiments|helped with the in vitro experiments and in vivo treatments	helped with the in vitro experiments and in vivo treatments	Performed the experiments	Investigation	YES
5829544	29527214	TS	PLoS52	performed all the experiments|helped with the in vitro experiments and in vivo treatments	performed all the experiments	Performed the experiments	Investigation	YES
5829544	29527214	TS	PLoS52	performed all the experiments|helped with the in vitro experiments and in vivo treatments	helped with the in vitro experiments and in vivo treatments	Performed the experiments	Investigation	YES
5809883	29433445	All authors	2	edited and approved the final version of the manuscript	edited and approved the final version of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5809883	29433445	HL	2	performed the bioinformatics analysis and wrote the manuscript	performed the bioinformatics analysis and wrote the manuscript	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5809883	29433445	MY	2	performed the bioinformatics analysis and wrote the manuscript	performed the bioinformatics analysis and wrote the manuscript	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5809883	29433445	X-HZ	2	designed the study, interpreted the data and thoroughly revised the manuscript	designed the study, interpreted the data and thoroughly revised the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
5809883	29433445	XW	2	isolated the strains and sequenced the genomic dna and analyzed the genomic data	isolated the strains and sequenced the genomic dna and analyzed the genomic data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
2001182	17940602	BE	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
2001182	17940602	BE	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2001182	17940602	CH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2001182	17940602	CH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2001182	17940602	CH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2001182	17940602	HD	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
2001182	17940602	JB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
2001182	17940602	JC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
2001182	17940602	JC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2001182	17940602	JS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2001182	17940602	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2001182	17940602	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2001182	17940602	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2001182	17940602	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2001182	17940602	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2001182	17940602	RS	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5962526	29785529	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5962526	29785529	CS	PLoS52	did the gene prediction|analyzed the data and wrote this manuscript	did the gene prediction	Analyzed the data	Formal analysis	YES
5962526	29785529	CS	PLoS52	did the gene prediction|analyzed the data and wrote this manuscript	analyzed the data and wrote this manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5962526	29785529	DW	PLoS52	helped with the glucan hydrolysis assay and antibody preparation	helped with the glucan hydrolysis assay and antibody preparation	Performed the experiments	Investigation	YES
5962526	29785529	GL	PLoS52	did the gene prediction	did the gene prediction	Analyzed the data	Formal analysis	YES
5962526	29785529	GX	PLoS52	conceived and designed the experiments|did most of the experiments|analyzed the data and wrote this manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5962526	29785529	GX	PLoS52	conceived and designed the experiments|did most of the experiments|analyzed the data and wrote this manuscript	did most of the experiments	Performed the experiments	Investigation	YES
5962526	29785529	GX	PLoS52	conceived and designed the experiments|did most of the experiments|analyzed the data and wrote this manuscript	analyzed the data and wrote this manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5962526	29785529	HF	PLoS52	helped with the antimicrobial activity assay	helped with the antimicrobial activity assay	Performed the experiments	Investigation	YES
5962526	29785529	JC	PLoS52	helped with the glucan hydrolysis assay and antibody preparation	helped with the glucan hydrolysis assay and antibody preparation	Performed the experiments	Investigation	YES
5962526	29785529	JW	PLoS52	conceived and designed the experiments|did most of the experiments|analyzed the data and wrote this manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5962526	29785529	JW	PLoS52	conceived and designed the experiments|did most of the experiments|analyzed the data and wrote this manuscript	did most of the experiments	Performed the experiments	Investigation	YES
5962526	29785529	JW	PLoS52	conceived and designed the experiments|did most of the experiments|analyzed the data and wrote this manuscript	analyzed the data and wrote this manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5962526	29785529	KL	PLoS52	conceived and designed the experiments|analyzed the data and wrote this manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5962526	29785529	KL	PLoS52	conceived and designed the experiments|analyzed the data and wrote this manuscript	analyzed the data and wrote this manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5962526	29785529	LW	PLoS52	helped with the antimicrobial activity assay	helped with the antimicrobial activity assay	Performed the experiments	Investigation	YES
5962526	29785529	LZ	PLoS52	did the gene prediction	did the gene prediction	Analyzed the data	Formal analysis	YES
5962526	29785529	RX	PLoS52	helped with the antimicrobial activity assay	helped with the antimicrobial activity assay	Performed the experiments	Investigation	YES
5962526	29785529	YJ	PLoS52	confirmed the expression and activity of the recombinant b-1,3-1,4-glucanase	confirmed the expression and activity of the recombinant b-1,3-1,4-glucanase	Performed the experiments	Investigation	YES
5962526	29785529	ZL	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6270846	24647034	All authors	2	participated in the drafting of this manuscript	participated in the drafting of this manuscript	Wrote the paper	Writing - Original Draft	YES
6270846	24647034	C.-Y.K.	2	performed all of the experiments in this study and contributed to the data analysis and interpretation	performed all of the experiments in this study and contributed to the data analysis and interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270846	24647034	C.-Y.L.	2	contributed to the experimental design of this study	contributed to the experimental design of this study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6270846	24647034	J.-J.S.	2	contributed to the experimental design of this study	contributed to the experimental design of this study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6270846	24647034	L.-M.K.	2	performed all of the experiments in this study and contributed to the data analysis and interpretation	performed all of the experiments in this study and contributed to the data analysis and interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270846	24647034	M.-F.H.	2	contributed to the experimental design of this study	contributed to the experimental design of this study	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6270846	24647034	T.-L.H.	2	participated in the conception, experimental design, and data interpretation of this study	participated in the conception, experimental design, and data interpretation of this study	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation|Methodology	YES
3628100	23554170	AH	2	provided app knockout mice	provided app knockout mice	Contributed reagents/materials/analysis tools	Resources	YES
3628100	23554170	All authors	2	critically discussed results	critically discussed results	-	-	NO
3628100	23554170	DT	2	performed immunofluorescence	performed immunofluorescence	Performed the experiments	Investigation	YES
3628100	23554170	FK	2	performed subcellular fractionation	performed subcellular fractionation	Performed the experiments	Investigation	YES
3628100	23554170	ID	2	provided 5xfad mice	provided 5xfad mice	Contributed reagents/materials/analysis tools	Resources	YES
3628100	23554170	JBD	2	designed peptides	designed peptides	Conceived and designed the experiments|Performed the experiments	Investigation	YES
3628100	23554170	JNO	2	designed research	designed research	Conceived and designed the experiments	Methodology	YES
3628100	23554170	LA	2	conducted measurements of cholesterol synthesis	conducted measurements of cholesterol synthesis	Performed the experiments	Investigation	YES
3628100	23554170	NP	2	designed research|performed immunofluorescence	designed research	Conceived and designed the experiments	Methodology	YES
3628100	23554170	NP	2	designed research|performed immunofluorescence	performed immunofluorescence	Performed the experiments	Investigation	YES
3628100	23554170	PG	2	provided inverted microscope for calcium imaging	provided inverted microscope for calcium imaging	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
3628100	23554170	RNA	2	viruses, calcium oscillations analysis	viruses, calcium oscillations analysis	-	-	NO
4418707	25938411	AD	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418707	25938411	GCR	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418707	25938411	JM	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418707	25938411	JM	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418707	25938411	MPB	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418707	25938411	QPP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418707	25938411	QPP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418707	25938411	QPP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418707	25938411	RM	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418707	25938411	TF	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418707	25938411	TF	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418707	25938411	US	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418707	25938411	XY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418707	25938411	XY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418707	25938411	XY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418707	25938411	XY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4083326	24998926	CL	2	study execution, manuscript discussing, planning and proofreading	study execution, manuscript discussing, planning and proofreading	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4083326	24998926	GM	2	planning, manuscript design, execution, analysis of the study, results discussing, manuscript writing	planning, manuscript design, execution, analysis of the study, results discussing, manuscript writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4083326	24998926	MAS	2	execution of the study	execution of the study	Performed the experiments	Investigation	YES
4083326	24998926	PC	2	execution and analysis of the study	execution and analysis of the study	Performed the experiments	Investigation	YES
4083326	24998926	SC	2	execution and analysis of the study	execution and analysis of the study	Performed the experiments	Investigation	YES
4083326	24998926	VM	2	execution of the study	execution of the study	Performed the experiments	Investigation	YES
5134258	27980788	ET	2	provided genetic analysis	provided genetic analysis	Performed the experiments	Investigation	YES
5134258	27980788	HK	2	provided genetic analysis	provided genetic analysis	Performed the experiments	Investigation	YES
5134258	27980788	HO	2	provided medicine for the patient and edited the draft of the manuscript	provided medicine for the patient and edited the draft of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5134258	27980788	IT	2	provided medicine for the patient and edited the draft of the manuscript	provided medicine for the patient and edited the draft of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5134258	27980788	KI	2	provided medicine for the patient and edited the draft of the manuscript	provided medicine for the patient and edited the draft of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5134258	27980788	KJ	2	provided medicine for the patient and edited the draft of the manuscript	provided medicine for the patient and edited the draft of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5134258	27980788	KO	2	provided medicine for the patient and edited the draft of the manuscript	provided medicine for the patient and edited the draft of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5134258	27980788	MS	2	provided medicine for the patient and edited the draft of the manuscript	provided medicine for the patient and edited the draft of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5134258	27980788	TK	2	provided medicine for the patient and wrote the manuscript as a corresponding author	provided medicine for the patient and wrote the manuscript as a corresponding author	Wrote the paper	Writing - Original Draft	YES
5134258	27980788	YM	2	provided medicine for the patient and edited the draft of the manuscript	provided medicine for the patient and edited the draft of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5134258	27980788	YY	2	provided medicine for the patient and wrote the manuscript as a corresponding author	provided medicine for the patient and wrote the manuscript as a corresponding author	Wrote the paper	Writing - Original Draft	YES
4655261	26636097	All authors	2	read and approved the paper	read and approved the paper	-	-	NO
4655261	26636097	Bin Zhu	2	participated in collection and/or assembly of data|participated in data analysis and interpretation|participated in statistical analysis	participated in collection and/or assembly of data	Performed the experiments	Investigation	YES
4655261	26636097	Bin Zhu	2	participated in collection and/or assembly of data|participated in data analysis and interpretation|participated in statistical analysis	participated in data analysis and interpretation	Analyzed the data	Formal analysis	YES
4655261	26636097	Bin Zhu	2	participated in collection and/or assembly of data|participated in data analysis and interpretation|participated in statistical analysis	participated in statistical analysis	Analyzed the data	Formal analysis	YES
4655261	26636097	Gutian Zhang	2	participated in collection and/or assembly of data|participated in data analysis and interpretation|participated in statistical analysis	participated in collection and/or assembly of data	Performed the experiments	Investigation	YES
4655261	26636097	Gutian Zhang	2	participated in collection and/or assembly of data|participated in data analysis and interpretation|participated in statistical analysis	participated in data analysis and interpretation	Analyzed the data	Formal analysis	YES
4655261	26636097	Gutian Zhang	2	participated in collection and/or assembly of data|participated in data analysis and interpretation|participated in statistical analysis	participated in statistical analysis	Analyzed the data	Formal analysis	YES
4655261	26636097	Hongqian Guo	2	participated in collection and/or assembly of data|participated in data analysis and interpretation|participated in statistical analysis	participated in collection and/or assembly of data	Performed the experiments	Investigation	YES
4655261	26636097	Hongqian Guo	2	participated in collection and/or assembly of data|participated in data analysis and interpretation|participated in statistical analysis	participated in data analysis and interpretation	Analyzed the data	Formal analysis	YES
4655261	26636097	Hongqian Guo	2	participated in collection and/or assembly of data|participated in data analysis and interpretation|participated in statistical analysis	participated in statistical analysis	Analyzed the data	Formal analysis	YES
4655261	26636097	Jian He	2	participated in collection and/or assembly of data|participated in data analysis and interpretation|participated in paper writing|participated in conception and design, financial support, and final approval of the paper|contributed equally to this work	participated in collection and/or assembly of data	Performed the experiments	Investigation	YES
4655261	26636097	Jian He	2	participated in collection and/or assembly of data|participated in data analysis and interpretation|participated in paper writing|participated in conception and design, financial support, and final approval of the paper|contributed equally to this work	participated in data analysis and interpretation	Analyzed the data	Formal analysis	YES
4655261	26636097	Jian He	2	participated in collection and/or assembly of data|participated in data analysis and interpretation|participated in paper writing|participated in conception and design, financial support, and final approval of the paper|contributed equally to this work	participated in paper writing	Wrote the paper	-	YES
4655261	26636097	Jian He	2	participated in collection and/or assembly of data|participated in data analysis and interpretation|participated in paper writing|participated in conception and design, financial support, and final approval of the paper|contributed equally to this work	participated in conception and design, financial support, and final approval of the paper	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
4655261	26636097	Jian He	2	participated in collection and/or assembly of data|participated in data analysis and interpretation|participated in paper writing|participated in conception and design, financial support, and final approval of the paper|contributed equally to this work	contributed equally to this work	-	-	NO
4655261	26636097	Kefeng Zhou	2	participated in collection and/or assembly of data|participated in data analysis and interpretation|participated in paper writing|participated in conception and design, financial support, and final approval of the paper|contributed equally to this work	participated in collection and/or assembly of data	Performed the experiments	Investigation	YES
4655261	26636097	Kefeng Zhou	2	participated in collection and/or assembly of data|participated in data analysis and interpretation|participated in paper writing|participated in conception and design, financial support, and final approval of the paper|contributed equally to this work	participated in data analysis and interpretation	Analyzed the data	Formal analysis	YES
4655261	26636097	Kefeng Zhou	2	participated in collection and/or assembly of data|participated in data analysis and interpretation|participated in paper writing|participated in conception and design, financial support, and final approval of the paper|contributed equally to this work	participated in paper writing	Wrote the paper	-	YES
4655261	26636097	Kefeng Zhou	2	participated in collection and/or assembly of data|participated in data analysis and interpretation|participated in paper writing|participated in conception and design, financial support, and final approval of the paper|contributed equally to this work	participated in conception and design, financial support, and final approval of the paper	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
4655261	26636097	Kefeng Zhou	2	participated in collection and/or assembly of data|participated in data analysis and interpretation|participated in paper writing|participated in conception and design, financial support, and final approval of the paper|contributed equally to this work	contributed equally to this work	-	-	NO
4655261	26636097	Tian Liu	2	participated in data analysis and interpretation|participated in paper writing|participated in conception and design, financial support, and final approval of the paper	participated in data analysis and interpretation	Analyzed the data	Formal analysis	YES
4655261	26636097	Tian Liu	2	participated in data analysis and interpretation|participated in paper writing|participated in conception and design, financial support, and final approval of the paper	participated in paper writing	Wrote the paper	-	YES
4655261	26636097	Tian Liu	2	participated in data analysis and interpretation|participated in paper writing|participated in conception and design, financial support, and final approval of the paper	participated in conception and design, financial support, and final approval of the paper	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
4655261	26636097	Weidong Gan	2	participated in collection and/or assembly of data|participated in data analysis and interpretation|participated in paper writing|participated in conception and design, financial support, and final approval of the paper	participated in collection and/or assembly of data	Performed the experiments	Investigation	YES
4655261	26636097	Weidong Gan	2	participated in collection and/or assembly of data|participated in data analysis and interpretation|participated in paper writing|participated in conception and design, financial support, and final approval of the paper	participated in data analysis and interpretation	Analyzed the data	Formal analysis	YES
4655261	26636097	Weidong Gan	2	participated in collection and/or assembly of data|participated in data analysis and interpretation|participated in paper writing|participated in conception and design, financial support, and final approval of the paper	participated in paper writing	Wrote the paper	-	YES
4655261	26636097	Weidong Gan	2	participated in collection and/or assembly of data|participated in data analysis and interpretation|participated in paper writing|participated in conception and design, financial support, and final approval of the paper	participated in conception and design, financial support, and final approval of the paper	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
4655261	26636097	Xiaogong Li	2	participated in collection and/or assembly of data|participated in data analysis and interpretation|participated in statistical analysis	participated in collection and/or assembly of data	Performed the experiments	Investigation	YES
4655261	26636097	Xiaogong Li	2	participated in collection and/or assembly of data|participated in data analysis and interpretation|participated in statistical analysis	participated in data analysis and interpretation	Analyzed the data	Formal analysis	YES
4655261	26636097	Xiaogong Li	2	participated in collection and/or assembly of data|participated in data analysis and interpretation|participated in statistical analysis	participated in statistical analysis	Analyzed the data	Formal analysis	YES
4655261	26636097	Zhengyang Zhou	2	participated in collection and/or assembly of data|participated in data analysis and interpretation|participated in paper writing|participated in conception and design, financial support, and final approval of the paper	participated in collection and/or assembly of data	Performed the experiments	Investigation	YES
4655261	26636097	Zhengyang Zhou	2	participated in collection and/or assembly of data|participated in data analysis and interpretation|participated in paper writing|participated in conception and design, financial support, and final approval of the paper	participated in data analysis and interpretation	Analyzed the data	Formal analysis	YES
4655261	26636097	Zhengyang Zhou	2	participated in collection and/or assembly of data|participated in data analysis and interpretation|participated in paper writing|participated in conception and design, financial support, and final approval of the paper	participated in paper writing	Wrote the paper	-	YES
4655261	26636097	Zhengyang Zhou	2	participated in collection and/or assembly of data|participated in data analysis and interpretation|participated in paper writing|participated in conception and design, financial support, and final approval of the paper	participated in conception and design, financial support, and final approval of the paper	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
5468698	28584181	A.A.C.	2	created the concept and designed the study|contributed to the subsequent analysis of the data and the writing of the manuscript	created the concept and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5468698	28584181	A.A.C.	2	created the concept and designed the study|contributed to the subsequent analysis of the data and the writing of the manuscript	contributed to the subsequent analysis of the data and the writing of the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
5468698	28584181	All three authors	2	reviewed the paper and approved the final draft for submission	reviewed the paper and approved the final draft for submission	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5468698	28584181	F.L.J.	2	created the concept and designed the study|undertook and oversaw data collection in the field|contributed to the subsequent analysis of the data and the writing of the manuscript	created the concept and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5468698	28584181	F.L.J.	2	created the concept and designed the study|undertook and oversaw data collection in the field|contributed to the subsequent analysis of the data and the writing of the manuscript	undertook and oversaw data collection in the field	Performed the experiments	Investigation|Supervision	YES
5468698	28584181	F.L.J.	2	created the concept and designed the study|undertook and oversaw data collection in the field|contributed to the subsequent analysis of the data and the writing of the manuscript	contributed to the subsequent analysis of the data and the writing of the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
5468698	28584181	J.L.N.W.	2	created the concept and designed the study|contributed to the subsequent analysis of the data and the writing of the manuscript	created the concept and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5468698	28584181	J.L.N.W.	2	created the concept and designed the study|contributed to the subsequent analysis of the data and the writing of the manuscript	contributed to the subsequent analysis of the data and the writing of the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
2001183	17925880	CW	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
2001183	17925880	CW	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2001183	17925880	HI	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
2001183	17925880	HI	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2001183	17925880	HJ	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
2001183	17925880	HJ	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2001183	17925880	HX	PLoS5	Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
2001183	17925880	HX	PLoS5	Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
2001183	17925880	HX	PLoS5	Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2001183	17925880	HX	PLoS5	Performed the experiments|Performed the experiments|Analyzed the data|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2001183	17925880	J-DL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2001183	17925880	J-DL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2001183	17925880	J-DL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2001183	17925880	JHL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2001183	17925880	JHL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2001183	17925880	JHL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2001183	17925880	JHL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2001183	17925880	PB	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
2001183	17925880	PB	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2001183	17925880	TK	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
2001183	17925880	TK	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2001183	17925880	UH	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
2001183	17925880	UH	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5809914	29433421	All authors	PLoS52	revised and approved the final draft	revised and approved the final draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5809914	29433421	KD	PLoS52	conceived and designed the study|analyzed the data|prepared the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5809914	29433421	KD	PLoS52	conceived and designed the study|analyzed the data|prepared the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5809914	29433421	KD	PLoS52	conceived and designed the study|analyzed the data|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5809914	29433421	QL	PLoS52	conceived and designed the study|analyzed the data|prepared the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5809914	29433421	QL	PLoS52	conceived and designed the study|analyzed the data|prepared the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5809914	29433421	QL	PLoS52	conceived and designed the study|analyzed the data|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5809914	29433421	SF	PLoS52	conceived and designed the study|analyzed the data|prepared the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5809914	29433421	SF	PLoS52	conceived and designed the study|analyzed the data|prepared the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5809914	29433421	SF	PLoS52	conceived and designed the study|analyzed the data|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5809914	29433421	WS	PLoS52	conceived and designed the study|analyzed the data|prepared the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5809914	29433421	WS	PLoS52	conceived and designed the study|analyzed the data|prepared the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5809914	29433421	WS	PLoS52	conceived and designed the study|analyzed the data|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5809914	29433421	XZ	PLoS52	conceived and designed the study|analyzed the data|prepared the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5809914	29433421	XZ	PLoS52	conceived and designed the study|analyzed the data|prepared the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5809914	29433421	XZ	PLoS52	conceived and designed the study|analyzed the data|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5829606	29527216	BKS	1	Contributed reagents/materials/analysis tools/equipment facilities	Contributed reagents/materials/analysis tools/equipment facilities	Contributed reagents/materials/analysis tools	Resources	YES
5829606	29527216	BNS	1	Conceived and designed the experiments, performed the experiments, and wrote the paper|Analysis of data	Conceived and designed the experiments, performed the experiments, and wrote the paper	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Writing - Original Draft	YES
5829606	29527216	BNS	1	Conceived and designed the experiments, performed the experiments, and wrote the paper|Analysis of data	Analysis of data	Analyzed the data	Formal analysis	YES
5829606	29527216	GS	1	Analysis of data	Analysis of data	Analyzed the data	Formal analysis	YES
5829606	29527216	HS	1	Contributed reagents/materials/analysis tools/equipment facilities	Contributed reagents/materials/analysis tools/equipment facilities	Contributed reagents/materials/analysis tools	Resources	YES
5829606	29527216	PD	1	Conceived and designed the experiments, performed the experiments, and wrote the paper|Contributed reagents/materials/analysis tools/equipment facilities|Analysis of data	Conceived and designed the experiments, performed the experiments, and wrote the paper	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Writing - Original Draft	YES
5829606	29527216	PD	1	Conceived and designed the experiments, performed the experiments, and wrote the paper|Contributed reagents/materials/analysis tools/equipment facilities|Analysis of data	Contributed reagents/materials/analysis tools/equipment facilities	Contributed reagents/materials/analysis tools	Resources	YES
5829606	29527216	PD	1	Conceived and designed the experiments, performed the experiments, and wrote the paper|Contributed reagents/materials/analysis tools/equipment facilities|Analysis of data	Analysis of data	Analyzed the data	Formal analysis	YES
6270847	24962393	NL	2	designed research, performed research, analyzed the data and wrote the paper	designed research, performed research, analyzed the data and wrote the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
6270847	24962393	NSL	2	designed research, performed research, analyzed the data and wrote the paper	designed research, performed research, analyzed the data and wrote the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
6270847	24962393	OK	2	designed research, performed research, analyzed the data and wrote the paper	designed research, performed research, analyzed the data and wrote the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5964051	29789978	All authors	2	have contributed to this research work|read and approved the final manuscript	have contributed to this research work	Performed the experiments	Investigation	YES
5964051	29789978	All authors	2	have contributed to this research work|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5964051	29789978	Felipe Buendia-Kandia	2	was supported by the iceel carnot institution	was supported by the iceel carnot institution	-	-	NO
4418709	25938229	CW	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418709	25938229	CW	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418709	25938229	CY	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418709	25938229	HW	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418709	25938229	HW	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418709	25938229	LD	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418709	25938229	SG	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418709	25938229	TY	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418709	25938229	YZ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418709	25938229	YZ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418709	25938229	YZ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418709	25938229	ZY	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418709	25938229	ZY	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418709	25938229	ZY	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5483515	28630152	The authors	2	jointly prepared the figures, wrote and revised the paper before finally approving it for publication	jointly prepared the figures, wrote and revised the paper before finally approving it for publication	Wrote the paper	Visualization|Writing - Original Draft|Writing - Review & Editing	YES
2001184	17940599	BC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Contributed to compilation of data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2001184	17940599	BC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Contributed to compilation of data	Analyzed the data	Analyzed the data	Formal analysis	YES
2001184	17940599	BC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Contributed to compilation of data	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2001184	17940599	BC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Contributed to compilation of data	Contributed to compilation of data	Contributed reagents/materials/analysis tools	Resources	YES
2001184	17940599	CM	PLoS5	Contributed to compilation of data	Contributed to compilation of data	Contributed reagents/materials/analysis tools	Resources	YES
2001184	17940599	JX	PLoS5	Conceived and designed the experiments|Contributed to compilation of data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2001184	17940599	JX	PLoS5	Conceived and designed the experiments|Contributed to compilation of data	Contributed to compilation of data	Contributed reagents/materials/analysis tools	Resources	YES
2001184	17940599	LL	PLoS5	Contributed to compilation of data	Contributed to compilation of data	Contributed reagents/materials/analysis tools	Resources	YES
2001184	17940599	ML	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Contributed to compilation of data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2001184	17940599	ML	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Contributed to compilation of data	Analyzed the data	Analyzed the data	Formal analysis	YES
2001184	17940599	ML	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Contributed to compilation of data	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2001184	17940599	ML	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Contributed to compilation of data	Contributed to compilation of data	Contributed reagents/materials/analysis tools	Resources	YES
2001184	17940599	WI	PLoS5	Contributed to compilation of data	Contributed to compilation of data	Contributed reagents/materials/analysis tools	Resources	YES
5829608	29527218	SH	2	undertaking si analysis	undertaking si analysis	-	-	NO
5829608	29527218	all authors	2	contributed to the interpretation and drafting of the manuscript	contributed to the interpretation and drafting of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5966368	29796879	All	2	the experimental procedures were carried out according to the local experimental animal care committee and approved by the ethics of the institutional committee	the experimental procedures were carried out according to the local experimental animal care committee and approved by the ethics of the institutional committee	Performed the experiments	Investigation	YES
5966368	29796879	All authors	2	shared equally in this work|read and approved the final manuscript	shared equally in this work	-	-	NO
5966368	29796879	All authors	2	shared equally in this work|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5966368	29796879	Scientific Research	2	at king saud university through a research group project	at king saud university through a research group project	-	-	NO
5966368	29796879	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5809918	29433420	All	2	listed authors edited and approved the final manuscript	listed authors edited and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5809918	29433420	CGC	2	conceived and designed the study and sampled the experimental animals	conceived and designed the study and sampled the experimental animals	Conceived and designed the experiments	Conceptualization|Methodology	YES
5809918	29433420	IRC	2	performed statistical analysis of proteomics data	performed statistical analysis of proteomics data	Analyzed the data	Formal analysis	YES
5809918	29433420	PDN	2	conceived and designed the study and sampled the experimental animals	conceived and designed the study and sampled the experimental animals	Conceived and designed the experiments	Conceptualization|Methodology	YES
5809918	29433420	RW	2	performed ms analysis	performed ms analysis	Performed the experiments	Investigation	YES
5809918	29433420	WGN	2	conceived and designed the study and sampled the experimental animals|performed the laboratory work|interpreted the data and wrote the manuscript	conceived and designed the study and sampled the experimental animals	Conceived and designed the experiments	Conceptualization|Methodology	YES
5809918	29433420	WGN	2	conceived and designed the study and sampled the experimental animals|performed the laboratory work|interpreted the data and wrote the manuscript	performed the laboratory work	Performed the experiments	Investigation	YES
5809918	29433420	WGN	2	conceived and designed the study and sampled the experimental animals|performed the laboratory work|interpreted the data and wrote the manuscript	interpreted the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5225584	28096999	K. Shibahashi	2	designed this study|conducted the literature search and data collection|performed the data analysis and interpreted the data	designed this study	Conceived and designed the experiments	Methodology	YES
5225584	28096999	K. Shibahashi	2	designed this study|conducted the literature search and data collection|performed the data analysis and interpreted the data	conducted the literature search and data collection	Performed the experiments	Formal analysis|Investigation	YES
5225584	28096999	K. Shibahashi	2	designed this study|conducted the literature search and data collection|performed the data analysis and interpreted the data	performed the data analysis and interpreted the data	Analyzed the data	Formal analysis	YES
5225584	28096999	K. Sugiyama	2	performed the data analysis and interpreted the data|critically revised the final manuscript	performed the data analysis and interpreted the data	Analyzed the data	Formal analysis	YES
5225584	28096999	K. Sugiyama	2	performed the data analysis and interpreted the data|critically revised the final manuscript	critically revised the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5225584	28096999	MK	2	performed the data analysis and interpreted the data|critically revised the final manuscript	performed the data analysis and interpreted the data	Analyzed the data	Formal analysis	YES
5225584	28096999	MK	2	performed the data analysis and interpreted the data|critically revised the final manuscript	critically revised the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5225584	28096999	YH	2	critically revised the final manuscript	critically revised the final manuscript	Wrote the paper	Writing - Review & Editing	YES
3628102	23483716	AS	2	designed all experiments|performed two photon experiments|performed behavioural experiments|analysed data and wrote the manuscript	designed all experiments	Conceived and designed the experiments	Methodology	YES
3628102	23483716	AS	2	designed all experiments|performed two photon experiments|performed behavioural experiments|analysed data and wrote the manuscript	performed two photon experiments	Performed the experiments	Investigation	YES
3628102	23483716	AS	2	designed all experiments|performed two photon experiments|performed behavioural experiments|analysed data and wrote the manuscript	performed behavioural experiments	Performed the experiments	Investigation	YES
3628102	23483716	AS	2	designed all experiments|performed two photon experiments|performed behavioural experiments|analysed data and wrote the manuscript	analysed data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3628102	23483716	All of the authors	2	contributed to the final version of the manuscript	contributed to the final version of the manuscript	-	-	NO
3628102	23483716	DT	2	performed behavioural experiments	performed behavioural experiments	Performed the experiments	Investigation	YES
3628102	23483716	FG	2	designed two photon experiments|performed two photon experiments	designed two photon experiments	Conceived and designed the experiments	Methodology	YES
3628102	23483716	FG	2	designed two photon experiments|performed two photon experiments	performed two photon experiments	Performed the experiments	Investigation	YES
3628102	23483716	MER	2	designed all experiments|analysed data and wrote the manuscript	designed all experiments	Conceived and designed the experiments	Methodology	YES
3628102	23483716	MER	2	designed all experiments|analysed data and wrote the manuscript	analysed data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3628102	23483716	WBG	2	designed two photon experiments	designed two photon experiments	Conceived and designed the experiments	Methodology	YES
4418711	25938236	PT	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418711	25938236	RW	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4418711	25938236	RW	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418711	25938236	SV	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418711	25938236	SV	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418711	25938236	VDT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418711	25938236	VDT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418711	25938236	VDT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418711	25938236	VDT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418711	25938236	VDT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418711	25938236	YP	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418711	25938236	YP	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2001185	17940600	JP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Wrote code	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2001185	17940600	JP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Wrote code	Analyzed the data	Analyzed the data	Formal analysis	YES
2001185	17940600	JP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Wrote code	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2001185	17940600	JP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Wrote code	Wrote code	Wrote the paper	Software|Writing - Original Draft	YES
2001185	17940600	KB	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2001185	17940600	KB	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2001185	17940600	LL	PLoS5	Contributed reagents/materials/analysis tools|Provided support, advice, and editing	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2001185	17940600	LL	PLoS5	Contributed reagents/materials/analysis tools|Provided support, advice, and editing	Provided support, advice, and editing	Wrote the paper	Writing - Review & Editing	YES
2001185	17940600	RW	PLoS5	Analyzed the data|Provided support, advice, and editing	Analyzed the data	Analyzed the data	Formal analysis	YES
2001185	17940600	RW	PLoS5	Analyzed the data|Provided support, advice, and editing	Provided support, advice, and editing	Wrote the paper	Writing - Review & Editing	YES
5483522	28630159	C.B.-J.	2	all contributed to the writing of this review|created all figures and the table	all contributed to the writing of this review	Wrote the paper	Writing - Review & Editing	YES
5483522	28630159	C.B.-J.	2	all contributed to the writing of this review|created all figures and the table	created all figures and the table	-	Visualization	YES
5483522	28630159	D.B.	2	all contributed to the writing of this review	all contributed to the writing of this review	Wrote the paper	Writing - Review & Editing	YES
5483522	28630159	M.A.D.	2	all contributed to the writing of this review	all contributed to the writing of this review	Wrote the paper	Writing - Review & Editing	YES
4083328	24998928	DVS	2	single particle tracking analysis	single particle tracking analysis	Performed the experiments	Investigation	YES
4083328	24998928	EB	2	experiments design, experimental strategy coordination	experiments design, experimental strategy coordination	Conceived and designed the experiments	Methodology|Project administration	YES
4083328	24998928	GACR	2	projects p302/10/1022 and p302/12/g157 coordination	projects p302/10/1022 and p302/12/g157 coordination	-	Project administration	YES
4083328	24998928	PS	2	immunofluorescence and intermediated irradiation of the cells with g-rays	immunofluorescence and intermediated irradiation of the cells with g-rays	Performed the experiments	Investigation	YES
4083328	24998928	SK	2	projects p302/10/1022 and p302/12/g157 coordination	projects p302/10/1022 and p302/12/g157 coordination	-	Project administration	YES
4083328	24998928	SL	2	immunofluorescence and intermediated irradiation of the cells with g-rays	immunofluorescence and intermediated irradiation of the cells with g-rays	Performed the experiments	Investigation	YES
4083328	24998928	UV-A	2	irradiation, immunofluorescence studies	irradiation, immunofluorescence studies	Performed the experiments	Investigation	YES
6270848	25072200	All authors	2	contributed to the draft of the article and approved the final manuscript	contributed to the draft of the article and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5237178	28101364	HT	2	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5237178	28101364	OMa	2	participated in the conception and design of the study, acquisition of data, interpretation of data analysis, statistical analysis, and drafting of the manuscript	participated in the conception and design of the study, acquisition of data, interpretation of data analysis, statistical analysis, and drafting of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5237178	28101364	OMi	2	participated in the conception and design of the study, interpretation of data analysis, and review of the manuscript	participated in the conception and design of the study, interpretation of data analysis, and review of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Review & Editing	YES
5237178	28101364	TR	2	participated in the conception and design of the study and review of the manuscript	participated in the conception and design of the study and review of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
5237178	28101364	TShima	2	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5237178	28101364	TShio	2	participated in the conception and design of the study, interpretation of data analysis, and review of the manuscript	participated in the conception and design of the study, interpretation of data analysis, and review of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Review & Editing	YES
5810021	29433427	GD	2	created the work-flow and processed the raw array data|developed the web interface|drafted the manuscript	created the work-flow and processed the raw array data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5810021	29433427	GD	2	created the work-flow and processed the raw array data|developed the web interface|drafted the manuscript	developed the web interface	Contributed reagents/materials/analysis tools	Software	YES
5810021	29433427	GD	2	created the work-flow and processed the raw array data|developed the web interface|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5810021	29433427	HC	2	conceived the study|drafted the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5810021	29433427	HC	2	conceived the study|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5810021	29433427	JY	2	created the work-flow and processed the raw array data|developed the web interface	created the work-flow and processed the raw array data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5810021	29433427	JY	2	created the work-flow and processed the raw array data|developed the web interface	developed the web interface	Contributed reagents/materials/analysis tools	Software	YES
5810021	29433427	QZ	2	developed the web interface	developed the web interface	Contributed reagents/materials/analysis tools	Software	YES
5810021	29433427	ZXX	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
3628103	23483710	BB	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
3628103	23483710	BV	PLoS52	designed research|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
3628103	23483710	BV	PLoS52	designed research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3628103	23483710	DJW	PLoS52	designed research	designed research	Conceived and designed the experiments	Methodology	YES
3628103	23483710	KA	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
3628103	23483710	LB	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
3628103	23483710	LCF	PLoS52	designed research|performed research|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
3628103	23483710	LCF	PLoS52	designed research|performed research|wrote the paper	performed research	Performed the experiments	Investigation	YES
3628103	23483710	LCF	PLoS52	designed research|performed research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3628103	23483710	SS	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
3628103	23483710	WP	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
3628103	23483710	all authors	PLoS52	analysed data	analysed data	Analyzed the data	Formal analysis	YES
5829619	29527217	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5829619	29527217	MH-H	PLoS52	designed the experiment, created the software, ran the data analysis and analyzed the data|wrote the paper	designed the experiment, created the software, ran the data analysis and analyzed the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Methodology|Software	YES
5829619	29527217	MH-H	PLoS52	designed the experiment, created the software, ran the data analysis and analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5829619	29527217	RL	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5829619	29527217	WG	PLoS52	edited the paper	edited the paper	Wrote the paper	Writing - Review & Editing	YES
5972131	29808438	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5972131	29808438	AnnaT	2	performed the part of experiments	performed the part of experiments	Performed the experiments	Investigation	YES
5972131	29808438	ArmenT	2	critically interpreted the results, provided discussion, revised and edited the manuscript	critically interpreted the results, provided discussion, revised and edited the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5972131	29808438	IB	2	was conceived and designed the experiments, performed the experiments, analyzed all data and interpreted the results, prepared and wrote the manuscript	was conceived and designed the experiments, performed the experiments, analyzed all data and interpreted the results, prepared and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5972131	29808438	LM	2	performed experiments and wrote the manuscript	performed experiments and wrote the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4194388	25308840	AKP	2	study concept and design|manuscript drafting|critical revision of the manuscript|study supervision	study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4194388	25308840	AKP	2	study concept and design|manuscript drafting|critical revision of the manuscript|study supervision	manuscript drafting	Wrote the paper	Writing - Original Draft	YES
4194388	25308840	AKP	2	study concept and design|manuscript drafting|critical revision of the manuscript|study supervision	critical revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4194388	25308840	AKP	2	study concept and design|manuscript drafting|critical revision of the manuscript|study supervision	study supervision	-	Supervision	YES
4194388	25308840	GM	2	study concept and design	study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4194388	25308840	JB	2	data collection	data collection	Performed the experiments	Investigation	YES
4194388	25308840	LD	2	study concept and design|critical revision of the manuscript	study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4194388	25308840	LD	2	study concept and design|critical revision of the manuscript	critical revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4194388	25308840	LM	2	study concept and design|manuscript drafting|critical revision of the manuscript	study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4194388	25308840	LM	2	study concept and design|manuscript drafting|critical revision of the manuscript	manuscript drafting	Wrote the paper	Writing - Original Draft	YES
4194388	25308840	LM	2	study concept and design|manuscript drafting|critical revision of the manuscript	critical revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4194388	25308840	TK	2	data collection|analysis and interpretation of data|manuscript drafting	data collection	Performed the experiments	Investigation	YES
4194388	25308840	TK	2	data collection|analysis and interpretation of data|manuscript drafting	analysis and interpretation of data	Analyzed the data	Formal analysis	YES
4194388	25308840	TK	2	data collection|analysis and interpretation of data|manuscript drafting	manuscript drafting	Wrote the paper	Writing - Original Draft	YES
4418712	25938230	JC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418712	25938230	JC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418712	25938230	JC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418712	25938230	MLM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418712	25938230	MLM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418712	25938230	MLM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418712	25938230	NRP	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418712	25938230	NRP	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418712	25938230	NRP	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418712	25938230	RSP	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418712	25938230	RSP	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418712	25938230	RSP	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418712	25938230	SH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418712	25938230	SH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418712	25938230	SH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418712	25938230	SH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418712	25938230	TB	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418712	25938230	TB	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418712	25938230	TB	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418712	25938230	THH	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418712	25938230	THH	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418712	25938230	THH	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418712	25938230	TS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418712	25938230	TS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418712	25938230	TS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418712	25938230	TS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418712	25938230	TWM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418712	25938230	TWM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418712	25938230	TWM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418712	25938230	TWM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2001186	17925874	CR	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2001186	17925874	CR	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2001186	17925874	EH	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2001186	17925874	MC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2001186	17925874	PZ	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2001186	17925874	PZ	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5498295	28673911	L.N.	2	contributed to writing the manuscript	contributed to writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5498295	28673911	P.D.	2	contributed to writing the manuscript	contributed to writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5498295	28673911	S.M.	2	contributed to writing the manuscript	contributed to writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5498295	28673911	S.S.K.	2	contributed to writing the manuscript	contributed to writing the manuscript	Wrote the paper	Writing - Original Draft	YES
6270849	24858269	Huiyuan Guo	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6270849	24858269	Huiyuan Guo	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270849	24858269	Jinwei Wu	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
6270849	24858269	Jinwei Wu	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
6270849	24858269	Kaixiang Liu	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
6270849	24858269	Kaixiang Liu	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
6270849	24858269	Mingliang Liu	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6270849	24858269	Mingliang Liu	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270849	24858269	Shihong Chen	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
6270849	24858269	Tingting Zhang	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
6270849	24858269	Tingting Zhang	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
6270849	24858269	Tingting Zhang	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270849	24858269	Yabin Lin	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
3628104	23526809	ABZ	2	conducted epidemiological follow up and isolated the strains	conducted epidemiological follow up and isolated the strains	Performed the experiments	Investigation	YES
3628104	23526809	AP	2	performed experiments, interpreted data and contributed to the manuscript	performed experiments, interpreted data and contributed to the manuscript	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3628104	23526809	ARL	2	performed experiments, interpreted data and contributed to the manuscript	performed experiments, interpreted data and contributed to the manuscript	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3628104	23526809	EMH	2	designed and performed analyses, interpreted data and wrote the manuscript	designed and performed analyses, interpreted data and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3628104	23526809	GKP	2	performed analyses and interpreted data and contributed to the manuscript	performed analyses and interpreted data and contributed to the manuscript	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3628104	23526809	JL	2	performed analyses and interpreted data and contributed to the manuscript	performed analyses and interpreted data and contributed to the manuscript	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3628104	23526809	JMC	2	conducted epidemiological follow up and isolated the strains	conducted epidemiological follow up and isolated the strains	Performed the experiments	Investigation	YES
3628104	23526809	JP	2	interpreted data and contributed to the manuscript	interpreted data and contributed to the manuscript	Analyzed the data	Formal analysis	YES
3628104	23526809	MAH	2	initiated and designed the study, interpreted data and wrote the manuscript	initiated and designed the study, interpreted data and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
3628104	23526809	MS	2	performed analyses and interpreted data and contributed to the manuscript	performed analyses and interpreted data and contributed to the manuscript	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3628104	23526809	MTGH	2	performed analyses and interpreted data and contributed to the manuscript	performed analyses and interpreted data and contributed to the manuscript	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3628104	23526809	OH	2	conducted epidemiological follow up and isolated the strains	conducted epidemiological follow up and isolated the strains	Performed the experiments	Investigation	YES
3628104	23526809	RLS	2	performed experiments, interpreted data and contributed to the manuscript	performed experiments, interpreted data and contributed to the manuscript	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3628104	23526809	RNZ	2	interpreted data and contributed to the manuscript	interpreted data and contributed to the manuscript	Analyzed the data	Formal analysis	YES
3628104	23526809	SJP	2	interpreted data and contributed to the manuscript	interpreted data and contributed to the manuscript	Analyzed the data	Formal analysis	YES
3628104	23526809	SRH	2	provided analytical tools	provided analytical tools	Contributed reagents/materials/analysis tools	Resources	YES
2001187	17925875	BS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2001187	17925875	BS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2001187	17925875	MS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2001187	17925875	MS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2001187	17925875	MS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5829626	29527215	BW	2	carried out most of the experiments|wrote the manuscript	carried out most of the experiments	Performed the experiments	Investigation	YES
5829626	29527215	BW	2	carried out most of the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5829626	29527215	NS	2	performed the quantitative rt pcr and analyzed the data	performed the quantitative rt pcr and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5829626	29527215	NW	2	grew the plant samples|collected all the phenotypic data	grew the plant samples	Performed the experiments	Investigation	YES
5829626	29527215	NW	2	grew the plant samples|collected all the phenotypic data	collected all the phenotypic data	Performed the experiments	Investigation	YES
5829626	29527215	QZ	2	grew the plant samples	grew the plant samples	Performed the experiments	Investigation	YES
5829626	29527215	ZK	2	wrote the manuscript|revised the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5829626	29527215	ZK	2	wrote the manuscript|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5810047	29433424	AG	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
5810047	29433424	AG	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5810047	29433424	BP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5810047	29433424	BP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
5810047	29433424	BP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5810047	29433424	BP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5810047	29433424	BP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5810047	29433424	PS	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5810047	29433424	PS	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
5810047	29433424	PS	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4194389	25308841	all authors	2	contributed equally and approve the final version	contributed equally and approve the final version	-	-	NO
5972140	29808440	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5972140	29808440	JLiang	2	carried out the biological and chemical studies	carried out the biological and chemical studies	Performed the experiments	Investigation	YES
5972140	29808440	JLiu	2	conceived of the study, participated in its design and coordination, and draft the manuscript	conceived of the study, participated in its design and coordination, and draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
5972140	29808440	TC	2	carried out the biological and chemical studies	carried out the biological and chemical studies	Performed the experiments	Investigation	YES
5972140	29808440	YH	2	carried out the biological and chemical studies	carried out the biological and chemical studies	Performed the experiments	Investigation	YES
4418713	25938514	CX	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418713	25938514	CX	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418713	25938514	CX	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418713	25938514	HZ	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4418713	25938514	HZ	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418713	25938514	ML	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418713	25938514	QC	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418713	25938514	QC	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4418713	25938514	QC	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418713	25938514	WL	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418713	25938514	WL	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418713	25938514	XX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418713	25938514	XX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418713	25938514	XX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418713	25938514	XX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418713	25938514	YL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4418713	25938514	YL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4418713	25938514	YL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418713	25938514	Yang Yang	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418713	25938514	Yang Yang	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418713	25938514	Yang Yang	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418713	25938514	Yangfang Yang	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418713	25938514	Yangfang Yang	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418713	25938514	ZL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4418713	25938514	ZL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4418713	25938514	ZL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418713	25938514	ZY	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
6270850	25486244	M.Y.	2	supervised the project and contributed to the manuscript development	supervised the project and contributed to the manuscript development	-	Supervision	YES
6270850	25486244	N.A.	2	supervised the project and contributed to the manuscript development	supervised the project and contributed to the manuscript development	-	Supervision	YES
6270850	25486244	S.H.	2	supervised the project and contributed to the manuscript development	supervised the project and contributed to the manuscript development	-	Supervision	YES
6270850	25486244	S.S.	2	supervised the project and contributed to the manuscript development	supervised the project and contributed to the manuscript development	-	Supervision	YES
6270850	25486244	T.K.	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6270850	25486244	T.S.	2	supervised the project and contributed to the manuscript development	supervised the project and contributed to the manuscript development	-	Supervision	YES
5251288	28127437	BMWS	2	performed the multiplex analysis and helped interpreting the data	performed the multiplex analysis and helped interpreting the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5251288	28127437	CSF	2	performed the multiplex analysis and helped interpreting the data	performed the multiplex analysis and helped interpreting the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5251288	28127437	JTK	2	wrote the manuscript and performed the in vitro ec experiments|treated the patient	wrote the manuscript and performed the in vitro ec experiments	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5251288	28127437	JTK	2	wrote the manuscript and performed the in vitro ec experiments|treated the patient	treated the patient	Performed the experiments	Investigation	YES
5251288	28127437	KT	2	wrote the manuscript and performed the in vitro ec experiments	wrote the manuscript and performed the in vitro ec experiments	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5251288	28127437	SD	2	wrote the manuscript and performed the in vitro ec experiments|treated the patient	wrote the manuscript and performed the in vitro ec experiments	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5251288	28127437	SD	2	wrote the manuscript and performed the in vitro ec experiments|treated the patient	treated the patient	Performed the experiments	Investigation	YES
3628105	23505062	AS	2	supervised the performed transplantation experiments with cells from luciferase mice and bioluminescence analysis under the|helped cm to set up facs-mediated isolation of sca1 pos cells from muscles|supervised them and wrote the manuscript	supervised the performed transplantation experiments with cells from luciferase mice and bioluminescence analysis under the	Performed the experiments	Investigation|Supervision	YES
3628105	23505062	AS	2	supervised the performed transplantation experiments with cells from luciferase mice and bioluminescence analysis under the|helped cm to set up facs-mediated isolation of sca1 pos cells from muscles|supervised them and wrote the manuscript	helped cm to set up facs-mediated isolation of sca1 pos cells from muscles	Performed the experiments	Investigation|Methodology	YES
3628105	23505062	AS	2	supervised the performed transplantation experiments with cells from luciferase mice and bioluminescence analysis under the|helped cm to set up facs-mediated isolation of sca1 pos cells from muscles|supervised them and wrote the manuscript	supervised them and wrote the manuscript	Wrote the paper	Supervision|Writing - Original Draft	YES
3628105	23505062	All the authors	2	discussed, commented the results and read the manuscript	discussed, commented the results and read the manuscript	-	-	NO
3628105	23505062	CM	2	made most of the experiments of the manuscripts with the|supervised them and wrote the manuscript	made most of the experiments of the manuscripts with the	-	-	NO
3628105	23505062	CM	2	made most of the experiments of the manuscripts with the|supervised them and wrote the manuscript	supervised them and wrote the manuscript	Wrote the paper	Supervision|Writing - Original Draft	YES
3628105	23505062	DS	2	helped cm to set up facs-mediated isolation of sca1 pos cells from muscles	helped cm to set up facs-mediated isolation of sca1 pos cells from muscles	Performed the experiments	Investigation|Methodology	YES
3628105	23505062	FACS	2	under the	under the	-	-	NO
3628105	23505062	GB	2	supervised the under the	supervised the under the	-	Supervision	YES
3628105	23505062	GM	2	helped cm to set up facs-mediated isolation of sca1 pos cells from muscles	helped cm to set up facs-mediated isolation of sca1 pos cells from muscles	Performed the experiments	Investigation|Methodology	YES
3628105	23505062	KJM	2	helped cm to set up facs-mediated isolation of sca1 pos cells from muscles	helped cm to set up facs-mediated isolation of sca1 pos cells from muscles	Performed the experiments	Investigation|Methodology	YES
3628105	23505062	LB	2	supervised the under the	supervised the under the	-	Supervision	YES
3628105	23505062	MT	2	performed transplantation experiments with cells from luciferase mice and bioluminescence analysis under the	performed transplantation experiments with cells from luciferase mice and bioluminescence analysis under the	Performed the experiments	Investigation	YES
3628105	23505062	SC	2	helped with the made most of the experiments of the manuscripts with the	helped with the made most of the experiments of the manuscripts with the	Performed the experiments	Investigation	YES
3628105	23505062	VS	2	helped with the made most of the experiments of the manuscripts with the	helped with the made most of the experiments of the manuscripts with the	Performed the experiments	Investigation	YES
4194390	25308842	AA	2	data acquisition and analysis|manuscript writing|experiments design, and manuscript supervision|contributed equally to the manuscript	data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4194390	25308842	AA	2	data acquisition and analysis|manuscript writing|experiments design, and manuscript supervision|contributed equally to the manuscript	manuscript writing	Wrote the paper	Writing - Original Draft	YES
4194390	25308842	AA	2	data acquisition and analysis|manuscript writing|experiments design, and manuscript supervision|contributed equally to the manuscript	experiments design, and manuscript supervision	Conceived and designed the experiments	Methodology|Supervision	YES
4194390	25308842	AA	2	data acquisition and analysis|manuscript writing|experiments design, and manuscript supervision|contributed equally to the manuscript	contributed equally to the manuscript	-	-	NO
4194390	25308842	ADC	2	experiments design, and manuscript supervision	experiments design, and manuscript supervision	Conceived and designed the experiments	Methodology|Supervision	YES
4194390	25308842	All authors	2	red and approved the final manuscript version	red and approved the final manuscript version	Wrote the paper	Writing - Review & Editing	YES
4194390	25308842	CB	2	data acquisition and analysis	data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4194390	25308842	EDV	2	data acquisition and analysis	data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4194390	25308842	FA	2	experiments preforming	experiments preforming	Performed the experiments	Investigation	YES
4194390	25308842	GC	2	data acquisition and analysis	data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4194390	25308842	GG	2	experiments preforming	experiments preforming	Performed the experiments	Investigation	YES
4194390	25308842	MRR	2	data acquisition and analysis|experiments design, and manuscript supervision|contributed equally to the manuscript	data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4194390	25308842	MRR	2	data acquisition and analysis|experiments design, and manuscript supervision|contributed equally to the manuscript	experiments design, and manuscript supervision	Conceived and designed the experiments	Methodology|Supervision	YES
4194390	25308842	MRR	2	data acquisition and analysis|experiments design, and manuscript supervision|contributed equally to the manuscript	contributed equally to the manuscript	-	-	NO
4194390	25308842	SM	2	manuscript writing|experiments design, and manuscript supervision	manuscript writing	Wrote the paper	Writing - Original Draft	YES
4194390	25308842	SM	2	manuscript writing|experiments design, and manuscript supervision	experiments design, and manuscript supervision	Conceived and designed the experiments	Methodology|Supervision	YES
4194390	25308842	VR	2	experiments preforming	experiments preforming	Performed the experiments	Investigation	YES
2001290	17925866	ARK	PLoS5	Performed the immunological tests	Performed the immunological tests	Performed the experiments	Investigation	YES
2001290	17925866	BG	PLoS5	Designed the study|Wrote the paper	Designed the study	Conceived and designed the experiments	Methodology	YES
2001290	17925866	BG	PLoS5	Designed the study|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2001290	17925866	GP	PLoS5	Designed the study|Performed the immunological tests	Designed the study	Conceived and designed the experiments	Methodology	YES
2001290	17925866	GP	PLoS5	Designed the study|Performed the immunological tests	Performed the immunological tests	Performed the experiments	Investigation	YES
2001290	17925866	LK	PLoS5	Was the clinical supervisor	Was the clinical supervisor	-	Supervision	YES
2001290	17925866	MM	PLoS5	Performed the immunological tests	Performed the immunological tests	Performed the experiments	Investigation	YES
2001290	17925866	MT	PLoS5	Designed the study	Designed the study	Conceived and designed the experiments	Methodology	YES
2001290	17925866	NW	PLoS5	Performed the immunological tests	Performed the immunological tests	Performed the experiments	Investigation	YES
2001290	17925866	PV	PLoS5	Performed the statistical analysis	Performed the statistical analysis	Analyzed the data	Formal analysis	YES
2001290	17925866	RZ	PLoS5	Designed the study	Designed the study	Conceived and designed the experiments	Methodology	YES
2001290	17925866	SLO	PLoS5	Performed the immunological tests	Performed the immunological tests	Performed the experiments	Investigation	YES
2001290	17925866	SS	PLoS5	Was responsible for all clinical affairs of the study	Was responsible for all clinical affairs of the study	-	-	NO
5834426	29535751	S-BZ	PLoS52	conceived and designed the research|analyzed the data	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5834426	29535751	S-BZ	PLoS52	conceived and designed the research|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5834426	29535751	TL	PLoS52	conceived and designed the research|analyzed the data	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5834426	29535751	TL	PLoS52	conceived and designed the research|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5834426	29535751	WH	PLoS52	conceived and designed the research|conducted the experiments|analyzed the data|wrote the first draft of the manuscript, which was intensively edited by all the authors	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5834426	29535751	WH	PLoS52	conceived and designed the research|conducted the experiments|analyzed the data|wrote the first draft of the manuscript, which was intensively edited by all the authors	conducted the experiments	Performed the experiments	Investigation	YES
5834426	29535751	WH	PLoS52	conceived and designed the research|conducted the experiments|analyzed the data|wrote the first draft of the manuscript, which was intensively edited by all the authors	analyzed the data	Analyzed the data	Formal analysis	YES
5834426	29535751	WH	PLoS52	conceived and designed the research|conducted the experiments|analyzed the data|wrote the first draft of the manuscript, which was intensively edited by all the authors	wrote the first draft of the manuscript, which was intensively edited by all the authors	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5834426	29535751	Y-JY	PLoS52	conducted the experiments|analyzed the data	conducted the experiments	Performed the experiments	Investigation	YES
5834426	29535751	Y-JY	PLoS52	conducted the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
6461117	31015941	A.C.	2	constructed the plasmids for the two-domain amyloid fusion proteins	constructed the plasmids for the two-domain amyloid fusion proteins	Performed the experiments	Investigation	YES
6461117	31015941	AFM	2	imaging and participate in most of the experiments	imaging and participate in most of the experiments	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
6461117	31015941	All authors	2	contributed to revising the manuscript	contributed to revising the manuscript	Wrote the paper	Writing - Review & Editing	YES
6461117	31015941	C.Z.	2	designed and participated in all the experiments|performed in analyzing all of the data|wrote the paper with	designed and participated in all the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6461117	31015941	C.Z.	2	designed and participated in all the experiments|performed in analyzing all of the data|wrote the paper with	performed in analyzing all of the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6461117	31015941	C.Z.	2	designed and participated in all the experiments|performed in analyzing all of the data|wrote the paper with	wrote the paper with	Wrote the paper	Writing - Original Draft	YES
6461117	31015941	M.K.C.	2	designed and participated in all the experiments|performed in analyzing all of the data|wrote the paper with	designed and participated in all the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6461117	31015941	M.K.C.	2	designed and participated in all the experiments|performed in analyzing all of the data|wrote the paper with	performed in analyzing all of the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6461117	31015941	M.K.C.	2	designed and participated in all the experiments|performed in analyzing all of the data|wrote the paper with	wrote the paper with	Wrote the paper	Writing - Original Draft	YES
6461117	31015941	Q.Q.	2	designed and participated in all the experiments|performed in analyzing all of the data|wrote the paper with	designed and participated in all the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6461117	31015941	Q.Q.	2	designed and participated in all the experiments|performed in analyzing all of the data|wrote the paper with	performed in analyzing all of the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6461117	31015941	Q.Q.	2	designed and participated in all the experiments|performed in analyzing all of the data|wrote the paper with	wrote the paper with	Wrote the paper	Writing - Original Draft	YES
6461117	31015941	T.G.	2	wrote the paper with	wrote the paper with	Wrote the paper	Writing - Original Draft	YES
6461117	31015941	X.R.G.	2	helped to collect the data of x-ray fibril diffraction|constructed the plasmids for the two-domain amyloid fusion proteins	helped to collect the data of x-ray fibril diffraction	Performed the experiments	Investigation	YES
6461117	31015941	X.R.G.	2	helped to collect the data of x-ray fibril diffraction|constructed the plasmids for the two-domain amyloid fusion proteins	constructed the plasmids for the two-domain amyloid fusion proteins	Performed the experiments	Investigation	YES
6461117	31015941	all authors	2	helped with the wrote the paper with	helped with the wrote the paper with	Wrote the paper	Writing - Original Draft	YES
4657062	26640786	Andras Rudolf	2	contributed equally to this work	contributed equally to this work	-	-	NO
4657062	26640786	Christoph Aufricht	2	contributed equally to this work	contributed equally to this work	-	-	NO
4657062	26640786	Janusz Witowski	2	contributed equally to this work	contributed equally to this work	-	-	NO
4657062	26640786	Klaus Kratochwill	2	contributed equally to this work	contributed equally to this work	-	-	NO
4657062	26640786	Rebecca Herzog	2	contributed equally to this work	contributed equally to this work	-	-	NO
4657062	26640786	Silvia Tarantino	2	contributed equally to this work	contributed equally to this work	-	-	NO
4418714	25938431	ACC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418714	25938431	ALRO	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4418714	25938431	ALRO	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418714	25938431	APB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418714	25938431	DRSM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4418714	25938431	DRSM	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418714	25938431	FTMC	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418714	25938431	FTMC	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418714	25938431	FZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418714	25938431	GFN	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418714	25938431	ICNP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418714	25938431	LKI	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418714	25938431	LV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418714	25938431	LV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418714	25938431	LV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418714	25938431	LV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418714	25938431	MACH	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4418714	25938431	MACH	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418714	25938431	ND	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418714	25938431	ND	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418714	25938431	RT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418714	25938431	RT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418714	25938431	RT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418714	25938431	RT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418714	25938431	RdG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418714	25938431	SCPL	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418714	25938431	SCPL	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418714	25938431	TAC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5516115	28717016	A.M.	2	wrote and revised the manuscript	wrote and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5516115	28717016	A.M.B.	2	wrote and revised the manuscript	wrote and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5516115	28717016	L.A.	2	wrote and revised the manuscript	wrote and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5516115	28717016	T.B.	2	designed the structure of the paper|wrote and revised the manuscript	designed the structure of the paper	Conceived and designed the experiments	-	YES
5516115	28717016	T.B.	2	designed the structure of the paper|wrote and revised the manuscript	wrote and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5810056	29433437	DWJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5810056	29433437	DWJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5810056	29433437	DWJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5810056	29433437	JHL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5810056	29433437	JHL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
5810056	29433437	JHL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5810056	29433437	SH	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
5810056	29433437	SH	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
3910275	24516367	All authors	2	read and approved the final paper	read and approved the final paper	-	-	NO
5976562	29846821	All	2	applicable international, national and/or institutional guidelines for the care and use of animals were followed	applicable international, national and/or institutional guidelines for the care and use of animals were followed	-	-	NO
5976562	29846821	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5976562	29846821	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
2002509	17940610	DW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
2002509	17940610	HE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2002509	17940610	HE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2002509	17940610	HE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2002509	17940610	HE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2002509	17940610	JC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2002509	17940610	JC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2002509	17940610	JC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2002509	17940610	MW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2002509	17940610	MW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2002509	17940610	MW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2002509	17940610	SM	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2002509	17940610	SM	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2002509	17940610	TT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2002509	17940610	TT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2002509	17940610	TT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2002509	17940610	TT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3628106	23526803	ACS	PLoS52	performed and interpreted the ultrastructural study	performed and interpreted the ultrastructural study	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3628106	23526803	FDB	PLoS52	conceived the study|analysed the data|wrote the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
3628106	23526803	FDB	PLoS52	conceived the study|analysed the data|wrote the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
3628106	23526803	FDB	PLoS52	conceived the study|analysed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3628106	23526803	JMGV	PLoS52	performed and interpreted the ultrastructural study	performed and interpreted the ultrastructural study	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3628106	23526803	JRP	PLoS52	designed experiments|analysed the data|wrote the manuscript	designed experiments	Conceived and designed the experiments	Methodology	YES
3628106	23526803	JRP	PLoS52	designed experiments|analysed the data|wrote the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
3628106	23526803	JRP	PLoS52	designed experiments|analysed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3628106	23526803	MAM	PLoS52	conceived the study|designed experiments|analysed the data|wrote the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
3628106	23526803	MAM	PLoS52	conceived the study|designed experiments|analysed the data|wrote the manuscript	designed experiments	Conceived and designed the experiments	Methodology	YES
3628106	23526803	MAM	PLoS52	conceived the study|designed experiments|analysed the data|wrote the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
3628106	23526803	MAM	PLoS52	conceived the study|designed experiments|analysed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4194391	25308843	All authors	2	have contributed to, seen and approved the manuscript	have contributed to, seen and approved the manuscript	-	-	NO
4194391	25308843	DOBE	2	contributed equally to this work|methods and experiments design, laboratory experiments, the data analysis and results interpretation|co-design, analysis discussion, interpretation, and presentation of all immunohistochemistry experiments|immunohistochemistry experiments design, quality assurance and control of each used antibody	contributed equally to this work	-	-	NO
4194391	25308843	DOBE	2	contributed equally to this work|methods and experiments design, laboratory experiments, the data analysis and results interpretation|co-design, analysis discussion, interpretation, and presentation of all immunohistochemistry experiments|immunohistochemistry experiments design, quality assurance and control of each used antibody	methods and experiments design, laboratory experiments, the data analysis and results interpretation	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
4194391	25308843	DOBE	2	contributed equally to this work|methods and experiments design, laboratory experiments, the data analysis and results interpretation|co-design, analysis discussion, interpretation, and presentation of all immunohistochemistry experiments|immunohistochemistry experiments design, quality assurance and control of each used antibody	co-design, analysis discussion, interpretation, and presentation of all immunohistochemistry experiments	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
4194391	25308843	DOBE	2	contributed equally to this work|methods and experiments design, laboratory experiments, the data analysis and results interpretation|co-design, analysis discussion, interpretation, and presentation of all immunohistochemistry experiments|immunohistochemistry experiments design, quality assurance and control of each used antibody	immunohistochemistry experiments design, quality assurance and control of each used antibody	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Validation	YES
4194391	25308843	JLS	2	research theme definition|methods and experiments design, laboratory experiments, the data analysis and results interpretation|manuscript writing	research theme definition	-	-	NO
4194391	25308843	JLS	2	research theme definition|methods and experiments design, laboratory experiments, the data analysis and results interpretation|manuscript writing	methods and experiments design, laboratory experiments, the data analysis and results interpretation	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
4194391	25308843	JLS	2	research theme definition|methods and experiments design, laboratory experiments, the data analysis and results interpretation|manuscript writing	manuscript writing	Wrote the paper	Writing - Original Draft	YES
4194391	25308843	KF	2	research theme definition|methods and experiments design, laboratory experiments, the data analysis and results interpretation|co-design, analysis discussion, interpretation, and presentation of all immunohistochemistry experiments|immunohistochemistry experiments design, quality assurance and control of each used antibody|manuscript writing	research theme definition	-	-	NO
4194391	25308843	KF	2	research theme definition|methods and experiments design, laboratory experiments, the data analysis and results interpretation|co-design, analysis discussion, interpretation, and presentation of all immunohistochemistry experiments|immunohistochemistry experiments design, quality assurance and control of each used antibody|manuscript writing	methods and experiments design, laboratory experiments, the data analysis and results interpretation	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
4194391	25308843	KF	2	research theme definition|methods and experiments design, laboratory experiments, the data analysis and results interpretation|co-design, analysis discussion, interpretation, and presentation of all immunohistochemistry experiments|immunohistochemistry experiments design, quality assurance and control of each used antibody|manuscript writing	co-design, analysis discussion, interpretation, and presentation of all immunohistochemistry experiments	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
4194391	25308843	KF	2	research theme definition|methods and experiments design, laboratory experiments, the data analysis and results interpretation|co-design, analysis discussion, interpretation, and presentation of all immunohistochemistry experiments|immunohistochemistry experiments design, quality assurance and control of each used antibody|manuscript writing	immunohistochemistry experiments design, quality assurance and control of each used antibody	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Validation	YES
4194391	25308843	KF	2	research theme definition|methods and experiments design, laboratory experiments, the data analysis and results interpretation|co-design, analysis discussion, interpretation, and presentation of all immunohistochemistry experiments|immunohistochemistry experiments design, quality assurance and control of each used antibody|manuscript writing	manuscript writing	Wrote the paper	Writing - Original Draft	YES
4194391	25308843	LFA	2	methods and experiments design, laboratory experiments, the data analysis and results interpretation	methods and experiments design, laboratory experiments, the data analysis and results interpretation	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
4194391	25308843	MDP	2	methods and experiments design, laboratory experiments, the data analysis and results interpretation|immunohistochemistry experiments design, quality assurance and control of each used antibody	methods and experiments design, laboratory experiments, the data analysis and results interpretation	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
4194391	25308843	MDP	2	methods and experiments design, laboratory experiments, the data analysis and results interpretation|immunohistochemistry experiments design, quality assurance and control of each used antibody	immunohistochemistry experiments design, quality assurance and control of each used antibody	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Validation	YES
4194391	25308843	MN	2	methods and experiments design, laboratory experiments, the data analysis and results interpretation|immunohistochemistry experiments design, quality assurance and control of each used antibody	methods and experiments design, laboratory experiments, the data analysis and results interpretation	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
4194391	25308843	MN	2	methods and experiments design, laboratory experiments, the data analysis and results interpretation|immunohistochemistry experiments design, quality assurance and control of each used antibody	immunohistochemistry experiments design, quality assurance and control of each used antibody	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Validation	YES
4194391	25308843	VVB	2	methods and experiments design, laboratory experiments, the data analysis and results interpretation	methods and experiments design, laboratory experiments, the data analysis and results interpretation	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
4194391	25308843	WRF	2	contributed equally to this work|methods and experiments design, laboratory experiments, the data analysis and results interpretation|co-design, analysis discussion, interpretation, and presentation of all immunohistochemistry experiments	contributed equally to this work	-	-	NO
4194391	25308843	WRF	2	contributed equally to this work|methods and experiments design, laboratory experiments, the data analysis and results interpretation|co-design, analysis discussion, interpretation, and presentation of all immunohistochemistry experiments	methods and experiments design, laboratory experiments, the data analysis and results interpretation	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
4194391	25308843	WRF	2	contributed equally to this work|methods and experiments design, laboratory experiments, the data analysis and results interpretation|co-design, analysis discussion, interpretation, and presentation of all immunohistochemistry experiments	co-design, analysis discussion, interpretation, and presentation of all immunohistochemistry experiments	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5834473	29535756	XH	2	wrote the manuscript|contributed to the discussion and approved the final manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5834473	29535756	XH	2	wrote the manuscript|contributed to the discussion and approved the final manuscript	contributed to the discussion and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5834473	29535756	XL	2	wrote the manuscript|contributed to the discussion and approved the final manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5834473	29535756	XL	2	wrote the manuscript|contributed to the discussion and approved the final manuscript	contributed to the discussion and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5264296	28138389	AV	PLoS52	designed the paper|wrote the paper	designed the paper	Conceived and designed the experiments	-	YES
5264296	28138389	AV	PLoS52	designed the paper|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5264296	28138389	All authors	PLoS52	critically reviewed the paper	critically reviewed the paper	Wrote the paper	Writing - Review & Editing	YES
5264296	28138389	DD	PLoS52	designed the paper	designed the paper	Conceived and designed the experiments	-	YES
5264296	28138389	ES	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5264296	28138389	MV	PLoS52	designed the paper	designed the paper	Conceived and designed the experiments	-	YES
5264296	28138389	SC	PLoS52	designed the paper	designed the paper	Conceived and designed the experiments	-	YES
5264296	28138389	SS	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270851	25153867	S.M.	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
4657069	26640788	Dan Wang	2	performed the experiment and analyzed the data	performed the experiment and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4657069	26640788	Hongmei Xia	2	performed the experiment and analyzed the data	performed the experiment and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4657069	26640788	Jianhua Ran	2	designed the experiments and wrote the paper	designed the experiments and wrote the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4657069	26640788	Junke Zhu	2	prepared figures 1 - 7	prepared figures 1 - 7	-	Visualization	YES
4657069	26640788	Xiaosong Li	2	designed the experiments and wrote the paper	designed the experiments and wrote the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4418715	25938466	ACM	PLoS5	Conceived and designed the experiments|Reviewed the draft	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418715	25938466	ACM	PLoS5	Conceived and designed the experiments|Reviewed the draft	Reviewed the draft	Wrote the paper	Writing - Original Draft	YES
4418715	25938466	AJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Reviewed the draft	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418715	25938466	AJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Reviewed the draft	Performed the experiments	Performed the experiments	Investigation	YES
4418715	25938466	AJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Reviewed the draft	Reviewed the draft	Wrote the paper	Writing - Original Draft	YES
4418715	25938466	AMA	PLoS5	Conceived and designed the experiments|Performed the experiments|Reviewed the draft	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418715	25938466	AMA	PLoS5	Conceived and designed the experiments|Performed the experiments|Reviewed the draft	Performed the experiments	Performed the experiments	Investigation	YES
4418715	25938466	AMA	PLoS5	Conceived and designed the experiments|Performed the experiments|Reviewed the draft	Reviewed the draft	Wrote the paper	Writing - Original Draft	YES
4418715	25938466	BA	PLoS5	Conceived and designed the experiments|Performed the experiments|Reviewed the draft	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418715	25938466	BA	PLoS5	Conceived and designed the experiments|Performed the experiments|Reviewed the draft	Performed the experiments	Performed the experiments	Investigation	YES
4418715	25938466	BA	PLoS5	Conceived and designed the experiments|Performed the experiments|Reviewed the draft	Reviewed the draft	Wrote the paper	Writing - Original Draft	YES
4418715	25938466	DB	PLoS5	Conceived and designed the experiments|Performed the experiments|Reviewed the draft	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418715	25938466	DB	PLoS5	Conceived and designed the experiments|Performed the experiments|Reviewed the draft	Performed the experiments	Performed the experiments	Investigation	YES
4418715	25938466	DB	PLoS5	Conceived and designed the experiments|Performed the experiments|Reviewed the draft	Reviewed the draft	Wrote the paper	Writing - Original Draft	YES
4418715	25938466	LD	PLoS5	Conceived and designed the experiments|Performed the experiments|Reviewed the draft	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418715	25938466	LD	PLoS5	Conceived and designed the experiments|Performed the experiments|Reviewed the draft	Performed the experiments	Performed the experiments	Investigation	YES
4418715	25938466	LD	PLoS5	Conceived and designed the experiments|Performed the experiments|Reviewed the draft	Reviewed the draft	Wrote the paper	Writing - Original Draft	YES
4418715	25938466	MCS	PLoS5	Conceived and designed the experiments|Performed the experiments|Reviewed the draft	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418715	25938466	MCS	PLoS5	Conceived and designed the experiments|Performed the experiments|Reviewed the draft	Performed the experiments	Performed the experiments	Investigation	YES
4418715	25938466	MCS	PLoS5	Conceived and designed the experiments|Performed the experiments|Reviewed the draft	Reviewed the draft	Wrote the paper	Writing - Original Draft	YES
4418715	25938466	MSC	PLoS5	Conceived and designed the experiments|Wrote the paper|Provided genetic analysis|Reviewed the draft	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418715	25938466	MSC	PLoS5	Conceived and designed the experiments|Wrote the paper|Provided genetic analysis|Reviewed the draft	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418715	25938466	MSC	PLoS5	Conceived and designed the experiments|Wrote the paper|Provided genetic analysis|Reviewed the draft	Provided genetic analysis	Performed the experiments	Investigation	YES
4418715	25938466	MSC	PLoS5	Conceived and designed the experiments|Wrote the paper|Provided genetic analysis|Reviewed the draft	Reviewed the draft	Wrote the paper	Writing - Original Draft	YES
4418715	25938466	PAK	PLoS5	Conceived and designed the experiments|Performed the experiments|Reviewed the draft	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418715	25938466	PAK	PLoS5	Conceived and designed the experiments|Performed the experiments|Reviewed the draft	Performed the experiments	Performed the experiments	Investigation	YES
4418715	25938466	PAK	PLoS5	Conceived and designed the experiments|Performed the experiments|Reviewed the draft	Reviewed the draft	Wrote the paper	Writing - Original Draft	YES
4418715	25938466	PG	PLoS5	Conceived and designed the experiments|Performed the experiments|Reviewed the draft	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418715	25938466	PG	PLoS5	Conceived and designed the experiments|Performed the experiments|Reviewed the draft	Performed the experiments	Performed the experiments	Investigation	YES
4418715	25938466	PG	PLoS5	Conceived and designed the experiments|Performed the experiments|Reviewed the draft	Reviewed the draft	Wrote the paper	Writing - Original Draft	YES
4418715	25938466	RBL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Reviewed the draft	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418715	25938466	RBL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Reviewed the draft	Analyzed the data	Analyzed the data	Formal analysis	YES
4418715	25938466	RBL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Reviewed the draft	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418715	25938466	RBL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Reviewed the draft	Reviewed the draft	Wrote the paper	Writing - Original Draft	YES
4418715	25938466	S. Saha	PLoS5	Conceived and designed the experiments|Analyzed the data|Reviewed the draft	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418715	25938466	S. Saha	PLoS5	Conceived and designed the experiments|Analyzed the data|Reviewed the draft	Analyzed the data	Analyzed the data	Formal analysis	YES
4418715	25938466	S. Saha	PLoS5	Conceived and designed the experiments|Analyzed the data|Reviewed the draft	Reviewed the draft	Wrote the paper	Writing - Original Draft	YES
4418715	25938466	S. Shrikhande	PLoS5	Conceived and designed the experiments|Performed the experiments|Reviewed the draft	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418715	25938466	S. Shrikhande	PLoS5	Conceived and designed the experiments|Performed the experiments|Reviewed the draft	Performed the experiments	Performed the experiments	Investigation	YES
4418715	25938466	S. Shrikhande	PLoS5	Conceived and designed the experiments|Performed the experiments|Reviewed the draft	Reviewed the draft	Wrote the paper	Writing - Original Draft	YES
4418715	25938466	SB	PLoS5	Conceived and designed the experiments|Performed the experiments|Reviewed the draft	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418715	25938466	SB	PLoS5	Conceived and designed the experiments|Performed the experiments|Reviewed the draft	Performed the experiments	Performed the experiments	Investigation	YES
4418715	25938466	SB	PLoS5	Conceived and designed the experiments|Performed the experiments|Reviewed the draft	Reviewed the draft	Wrote the paper	Writing - Original Draft	YES
4418715	25938466	VAP	PLoS5	Conceived and designed the experiments|Performed the experiments|Provided genetic analysis|Reviewed the draft	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418715	25938466	VAP	PLoS5	Conceived and designed the experiments|Performed the experiments|Provided genetic analysis|Reviewed the draft	Performed the experiments	Performed the experiments	Investigation	YES
4418715	25938466	VAP	PLoS5	Conceived and designed the experiments|Performed the experiments|Provided genetic analysis|Reviewed the draft	Provided genetic analysis	Performed the experiments	Investigation	YES
4418715	25938466	VAP	PLoS5	Conceived and designed the experiments|Performed the experiments|Provided genetic analysis|Reviewed the draft	Reviewed the draft	Wrote the paper	Writing - Original Draft	YES
5984612	29858705	All	2	datasets supporting the conclusions of this article are available in the manuscript	datasets supporting the conclusions of this article are available in the manuscript	-	-	NO
5984612	29858705	All authors	2	participated in analysis and interpretation of data and drafting the manuscript|read and approved the final manuscript	participated in analysis and interpretation of data and drafting the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5984612	29858705	All authors	2	participated in analysis and interpretation of data and drafting the manuscript|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5984612	29858705	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5810182	29426279	All authors	2	were responsible for critical review and approval of the manuscript	were responsible for critical review and approval of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5810182	29426279	AvdE	2	were responsible for the study design|contributed to the interpretation of the data	were responsible for the study design	Conceived and designed the experiments	Methodology	YES
5810182	29426279	AvdE	2	were responsible for the study design|contributed to the interpretation of the data	contributed to the interpretation of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5810182	29426279	BV	2	were responsible for the study design|were responsible for the genome analysis|contributed to the interpretation of the data|were responsible for the first draft of the manuscript	were responsible for the study design	Conceived and designed the experiments	Methodology	YES
5810182	29426279	BV	2	were responsible for the study design|were responsible for the genome analysis|contributed to the interpretation of the data|were responsible for the first draft of the manuscript	were responsible for the genome analysis	-	-	NO
5810182	29426279	BV	2	were responsible for the study design|were responsible for the genome analysis|contributed to the interpretation of the data|were responsible for the first draft of the manuscript	contributed to the interpretation of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5810182	29426279	BV	2	were responsible for the study design|were responsible for the genome analysis|contributed to the interpretation of the data|were responsible for the first draft of the manuscript	were responsible for the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
5810182	29426279	KAJ	2	were responsible for the study design|contributed to the interpretation of the data|were responsible for the first draft of the manuscript	were responsible for the study design	Conceived and designed the experiments	Methodology	YES
5810182	29426279	KAJ	2	were responsible for the study design|contributed to the interpretation of the data|were responsible for the first draft of the manuscript	contributed to the interpretation of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5810182	29426279	KAJ	2	were responsible for the study design|contributed to the interpretation of the data|were responsible for the first draft of the manuscript	were responsible for the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
5810182	29426279	MCJM	2	were responsible for the study design|contributed to the interpretation of the data|were responsible for the first draft of the manuscript	were responsible for the study design	Conceived and designed the experiments	Methodology	YES
5810182	29426279	MCJM	2	were responsible for the study design|contributed to the interpretation of the data|were responsible for the first draft of the manuscript	contributed to the interpretation of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5810182	29426279	MCJM	2	were responsible for the study design|contributed to the interpretation of the data|were responsible for the first draft of the manuscript	were responsible for the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
5810182	29426279	OBH	2	were responsible for the study design|were responsible for the genome analysis|contributed to the interpretation of the data|were responsible for the first draft of the manuscript	were responsible for the study design	Conceived and designed the experiments	Methodology	YES
5810182	29426279	OBH	2	were responsible for the study design|were responsible for the genome analysis|contributed to the interpretation of the data|were responsible for the first draft of the manuscript	were responsible for the genome analysis	-	-	NO
5810182	29426279	OBH	2	were responsible for the study design|were responsible for the genome analysis|contributed to the interpretation of the data|were responsible for the first draft of the manuscript	contributed to the interpretation of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5810182	29426279	OBH	2	were responsible for the study design|were responsible for the genome analysis|contributed to the interpretation of the data|were responsible for the first draft of the manuscript	were responsible for the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
5810182	29426279	SMB	2	were responsible for the study design|contributed to the interpretation of the data|were responsible for the first draft of the manuscript	were responsible for the study design	Conceived and designed the experiments	Methodology	YES
5810182	29426279	SMB	2	were responsible for the study design|contributed to the interpretation of the data|were responsible for the first draft of the manuscript	contributed to the interpretation of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5810182	29426279	SMB	2	were responsible for the study design|contributed to the interpretation of the data|were responsible for the first draft of the manuscript	were responsible for the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
5810182	29426279	YP	2	were responsible for the study design|contributed to the interpretation of the data|were responsible for the first draft of the manuscript	were responsible for the study design	Conceived and designed the experiments	Methodology	YES
5810182	29426279	YP	2	were responsible for the study design|contributed to the interpretation of the data|were responsible for the first draft of the manuscript	contributed to the interpretation of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5810182	29426279	YP	2	were responsible for the study design|contributed to the interpretation of the data|were responsible for the first draft of the manuscript	were responsible for the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
2002510	17940607	DL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2002510	17940607	DL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2002510	17940607	DL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2002510	17940607	DL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2002510	17940607	MP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2002510	17940607	MP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2002510	17940607	MP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2002510	17940607	MP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2002510	17940607	PK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2002510	17940607	PK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2002510	17940607	PK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2002510	17940607	PK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2002510	17940607	RL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2002510	17940607	RL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2002510	17940607	RL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2002510	17940607	RL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2002510	17940607	SA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2002510	17940607	SA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2002510	17940607	SA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2002510	17940607	SA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2002510	17940607	SA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2002510	17940607	SF	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
2002510	17940607	SF	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
2002510	17940607	SF	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2002510	17940607	SG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2002510	17940607	SG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
2002510	17940607	SG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2002510	17940607	TL	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2002510	17940607	TL	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2002510	17940607	TL	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2002510	17940607	TL	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2002510	17940607	TL	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2002510	17940607	TL	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2002510	17940607	TL	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3628107	23460527	AC	2	designed and performed experiments, analysed data and wrote the paper	designed and performed experiments, analysed data and wrote the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
3628107	23460527	AP	2	analysed human samples	analysed human samples	-	-	NO
3628107	23460527	BP	2	synthesized and provided the sf-1-066 inhibitor	synthesized and provided the sf-1-066 inhibitor	Performed the experiments	Investigation	YES
3628107	23460527	FM	2	performed th1/th2/th17 and eam experiments	performed th1/th2/th17 and eam experiments	Performed the experiments	Investigation	YES
3628107	23460527	MF	2	performed ihc analyses	performed ihc analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3628107	23460527	MM	2	performed echocardiography studies	performed echocardiography studies	Performed the experiments	Investigation	YES
3628107	23460527	OJ	2	the mass spectrometry	the mass spectrometry	Performed the experiments	Investigation	YES
3628107	23460527	PC	2	performed ihc analyses	performed ihc analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3628107	23460527	PG	2	synthesized and provided the sf-1-066 inhibitor	synthesized and provided the sf-1-066 inhibitor	Performed the experiments	Investigation	YES
3628107	23460527	RL	2	made conceptual contributions to the studies|analysed confocal data	made conceptual contributions to the studies	Conceived and designed the experiments	Conceptualization	YES
3628107	23460527	RL	2	made conceptual contributions to the studies|analysed confocal data	analysed confocal data	Analyzed the data	Formal analysis	YES
3628107	23460527	SFl	2	synthesized and provided the sf-1-066 inhibitor	synthesized and provided the sf-1-066 inhibitor	Performed the experiments	Investigation	YES
3628107	23460527	SH	2	made conceptual contributions to the studies|analysed human samples	made conceptual contributions to the studies	Conceived and designed the experiments	Conceptualization	YES
3628107	23460527	SH	2	made conceptual contributions to the studies|analysed human samples	analysed human samples	-	-	NO
3628107	23460527	VP	2	designed the project and the experiments, analysed data and wrote the paper	designed the project and the experiments, analysed data and wrote the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5834478	29535745	DH	2	conceived the idea, formulated the hypothesis, and wrote the manuscript	conceived the idea, formulated the hypothesis, and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5282695	28289544	MH	2	wrote the manuscript and approved the final manuscript	wrote the manuscript and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6270853	25111026	A. Schulze	2	interpreted the results and cooperated in the preparation of the manuscript	interpreted the results and cooperated in the preparation of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6270853	25111026	D. Schlosser	2	interpreted the results and cooperated in the preparation of the manuscript	interpreted the results and cooperated in the preparation of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6270853	25111026	E. Jahangiri	2	interpreted the results and cooperated in the preparation of the manuscript	interpreted the results and cooperated in the preparation of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6270853	25111026	I. Thomas	2	performed the membrane modification reactions as well as the membrane investigation	performed the membrane modification reactions as well as the membrane investigation	Performed the experiments	Investigation	YES
6270853	25111026	K. Hausmann	2	carried out the cryogel synthesis and investigation	carried out the cryogel synthesis and investigation	Performed the experiments	Investigation	YES
6270853	25111026	S. Reichelt	2	interpreted the results and cooperated in the preparation of the manuscript	interpreted the results and cooperated in the preparation of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4418716	25938578	HAAK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418716	25938578	HAAK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418716	25938578	HAAK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418716	25938578	HAAK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418716	25938578	HAAK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418716	25938578	JI	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418716	25938578	UN	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418716	25938578	WA	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418716	25938578	WA	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5984613	29858922	AHO	2	planned the experiments and wrote the manuscript|performed the experiments and analysed the data	planned the experiments and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5984613	29858922	AHO	2	planned the experiments and wrote the manuscript|performed the experiments and analysed the data	performed the experiments and analysed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5984613	29858922	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5984613	29858922	CHE	2	was responsible for initiation and supervision of the study	was responsible for initiation and supervision of the study	-	Supervision	YES
5984613	29858922	OSP	2	planned the experiments and wrote the manuscript	planned the experiments and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5811955	29439662	CT	2	contributed to the data analysis and manuscript preparation	contributed to the data analysis and manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5811955	29439662	LB	2	contributed to the data analysis and manuscript preparation	contributed to the data analysis and manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5811955	29439662	RD	2	supervised the whole study and revised the manuscript	supervised the whole study and revised the manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
5811955	29439662	SL	2	contributed to the data analysis and manuscript preparation	contributed to the data analysis and manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5811955	29439662	TZ	2	contributed to the data analysis and manuscript preparation	contributed to the data analysis and manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5811955	29439662	ZL	2	supervised the whole study and revised the manuscript	supervised the whole study and revised the manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
5811955	29439662	ZY	2	performed the major part of data analysis of this work and drafted the manuscript	performed the major part of data analysis of this work and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4194392	25308844	AO	2	conceived, carried out experiments and analyzed data|equally contributed to the work	conceived, carried out experiments and analyzed data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation	YES
4194392	25308844	AO	2	conceived, carried out experiments and analyzed data|equally contributed to the work	equally contributed to the work	-	-	NO
4194392	25308844	All authors	2	were involved in writing the paper and gave final approval of the submitted and published versions	were involved in writing the paper and gave final approval of the submitted and published versions	Wrote the paper	Writing - Original Draft	YES
4194392	25308844	EB	2	conceived, carried out experiments and analyzed data	conceived, carried out experiments and analyzed data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation	YES
4194392	25308844	IT	2	carried out experiments and analyzed data	carried out experiments and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4194392	25308844	MS	2	conceived, carried out experiments and analyzed data|equally contributed to the work	conceived, carried out experiments and analyzed data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation	YES
4194392	25308844	MS	2	conceived, carried out experiments and analyzed data|equally contributed to the work	equally contributed to the work	-	-	NO
4194392	25308844	SB	2	carried out experiments and analyzed data	carried out experiments and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3628108	23526793	CCY	PLoS52	contributed reagents/materials/analysis tools	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
3628108	23526793	CSW	PLoS52	analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
3628108	23526793	JLH	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3628108	23526793	JNC	PLoS52	analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
3628108	23526793	MCH	PLoS52	conceived and designed the experiments|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
3628108	23526793	MCH	PLoS52	conceived and designed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3628108	23526793	RHC	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
3628108	23526793	SPY	PLoS52	contributed reagents/materials/analysis tools	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
3628108	23526793	SYC	PLoS52	analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
3628108	23526793	ShiCH	PLoS52	contributed reagents/materials/analysis tools	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
3628108	23526793	ShuCH	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
3628108	23526793	WCS	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
3628108	23526793	WJC	PLoS52	analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
3628108	23526793	WL	PLoS52	contributed reagents/materials/analysis tools	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
3628108	23526793	YHL	PLoS52	analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
3628108	23526793	YJT	PLoS52	analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
3628108	23526793	YLY	PLoS52	conceived and designed the experiments|performed the experiments|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
3628108	23526793	YLY	PLoS52	conceived and designed the experiments|performed the experiments|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
3628108	23526793	YLY	PLoS52	conceived and designed the experiments|performed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5540864	28760765	T.H.	2	designed the study|designed the research tools|wrote the paper and approved the final version	designed the study	Conceived and designed the experiments	Methodology	YES
5540864	28760765	T.H.	2	designed the study|designed the research tools|wrote the paper and approved the final version	designed the research tools	Conceived and designed the experiments	Methodology	YES
5540864	28760765	T.H.	2	designed the study|designed the research tools|wrote the paper and approved the final version	wrote the paper and approved the final version	Wrote the paper	Writing - Original Draft	YES
5540864	28760765	Z.X.D.	2	designed the research tools|took the lead on the data collection, data entry and analysis|wrote the paper and approved the final version	designed the research tools	Conceived and designed the experiments	Methodology	YES
5540864	28760765	Z.X.D.	2	designed the research tools|took the lead on the data collection, data entry and analysis|wrote the paper and approved the final version	took the lead on the data collection, data entry and analysis	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5540864	28760765	Z.X.D.	2	designed the research tools|took the lead on the data collection, data entry and analysis|wrote the paper and approved the final version	wrote the paper and approved the final version	Wrote the paper	Writing - Original Draft	YES
5834487	29535742	GD	2	conceived the study and designed the experiments|carried out the experiments and analyzed the data|wrote the manuscript	conceived the study and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5834487	29535742	GD	2	conceived the study and designed the experiments|carried out the experiments and analyzed the data|wrote the manuscript	carried out the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5834487	29535742	GD	2	conceived the study and designed the experiments|carried out the experiments and analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5834487	29535742	JS	2	conceived the study and designed the experiments|carried out the experiments and analyzed the data	conceived the study and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5834487	29535742	JS	2	conceived the study and designed the experiments|carried out the experiments and analyzed the data	carried out the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5834487	29535742	JW	2	carried out the experiments and analyzed the data	carried out the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5834487	29535742	JZ	2	conceived the study and designed the experiments|carried out the experiments and analyzed the data|wrote the manuscript	conceived the study and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5834487	29535742	JZ	2	conceived the study and designed the experiments|carried out the experiments and analyzed the data|wrote the manuscript	carried out the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5834487	29535742	JZ	2	conceived the study and designed the experiments|carried out the experiments and analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5834487	29535742	KW	2	carried out the experiments and analyzed the data	carried out the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5834487	29535742	QY	2	carried out the experiments and analyzed the data	carried out the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5834487	29535742	QZ	2	carried out the experiments and analyzed the data	carried out the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5834487	29535742	RM	2	carried out the experiments and analyzed the data	carried out the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4418717	25938429	AS	PLoS5	Analyzed the data|Wrote the paper|Performed the analyses	Analyzed the data	Analyzed the data	Formal analysis	YES
4418717	25938429	AS	PLoS5	Analyzed the data|Wrote the paper|Performed the analyses	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418717	25938429	AS	PLoS5	Analyzed the data|Wrote the paper|Performed the analyses	Performed the analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4418717	25938429	BB	PLoS5	Conceived and designed the experiments|Analyzed the data|Performed the analyses|Commented on the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418717	25938429	BB	PLoS5	Conceived and designed the experiments|Analyzed the data|Performed the analyses|Commented on the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4418717	25938429	BB	PLoS5	Conceived and designed the experiments|Analyzed the data|Performed the analyses|Commented on the manuscript	Performed the analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4418717	25938429	BB	PLoS5	Conceived and designed the experiments|Analyzed the data|Performed the analyses|Commented on the manuscript	Commented on the manuscript	-	-	NO
4418717	25938429	CM	PLoS5	Analyzed the data|Commented on the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4418717	25938429	CM	PLoS5	Analyzed the data|Commented on the manuscript	Commented on the manuscript	-	-	NO
4418717	25938429	DK	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418717	25938429	DK	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418717	25938429	EMF	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418717	25938429	EMF	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418717	25938429	EO	PLoS5	Commented on the manuscript	Commented on the manuscript	-	-	NO
4418717	25938429	KS	PLoS5	Analyzed the data|Commented on the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4418717	25938429	KS	PLoS5	Analyzed the data|Commented on the manuscript	Commented on the manuscript	-	-	NO
4418717	25938429	MBB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Performed the analyses	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418717	25938429	MBB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Performed the analyses	Analyzed the data	Analyzed the data	Formal analysis	YES
4418717	25938429	MBB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Performed the analyses	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418717	25938429	MBB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Performed the analyses	Performed the analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4418717	25938429	RPB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418717	25938429	RPB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418717	25938429	RPB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418717	25938429	TA	PLoS5	Commented on the manuscript	Commented on the manuscript	-	-	NO
6270854	24731985	C. S. Cunha	7	conclusions	conclusions	-	-	NO
6270854	24731985	Fabricio C. Machado	7	Experimental--cytotoxic activity; Mario M. Martins, Claudio V. da Silva: Discussion of the cytotoxic activity results; Luis C. S. Cunha, Carlos	Experimental--cytotoxic activity; Mario M. Martins, Claudio V. da Silva: Discussion of the cytotoxic activity results; Luis C. S. Cunha, Carlos	-	-	NO
6270854	24731985	H. G. Martins	7	Discussion of the antimicrobial activity results; Francisco J. T. de Aquino, Alberto de Oliveira, Evandro A. Nascimento, Fabiana B. Furtado, Luis	Discussion of the antimicrobial activity results; Francisco J. T. de Aquino, Alberto de Oliveira, Evandro A. Nascimento, Fabiana B. Furtado, Luis	Performed the experiments	Investigation	YES
6270854	24731985	Luis F. Leandro	7	Experimental--antimicrobial activity	Experimental--antimicrobial activity	Performed the experiments	Investigation	YES
6270854	24731985	Mario M. Martins	7	Experimental--cytotoxic activity; Mario M. Martins, Claudio V. da Silva: Discussion of the cytotoxic activity results; Luis C. S. Cunha, Carlos	Experimental--cytotoxic activity; Mario M. Martins, Claudio V. da Silva: Discussion of the cytotoxic activity results; Luis C. S. Cunha, Carlos	-	-	NO
2002512	17940612	CS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2002512	17940612	CS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
2002512	17940612	CS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2002512	17940612	JM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
2002512	17940612	MG	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
2002512	17940612	MG	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2002512	17940612	PS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2002512	17940612	PS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2002512	17940612	PS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4194393	25308845	BL	2	language and correction, partly statistical analysis, preparation of revised manuscript	language and correction, partly statistical analysis, preparation of revised manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
4194393	25308845	EM	2	photos preparation, preparation of revised manuscript	photos preparation, preparation of revised manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4194393	25308845	KM	2	preparation of figures and references, language correction	preparation of figures and references, language correction	-	Visualization	YES
4194393	25308845	KZK	2	project supervisor	project supervisor	-	Supervision	YES
4194393	25308845	MM	2	quantification of immunogold particles	quantification of immunogold particles	Performed the experiments	Investigation	YES
4194393	25308845	ROS	2	evaluation, cell culture, statistical analysis, preparation of revised manuscript	evaluation, cell culture, statistical analysis, preparation of revised manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
4194393	25308845	WG	2	preparation of figures and tables	preparation of figures and tables	-	Visualization	YES
5984614	29858695	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5984614	29858695	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
3628109	23554169	AC	2	conceived and designed experiments|gave comments on the manuscript	conceived and designed experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
3628109	23554169	AC	2	conceived and designed experiments|gave comments on the manuscript	gave comments on the manuscript	-	-	NO
3628109	23554169	ASA	2	conceived and designed experiments|wrote the manuscript	conceived and designed experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
3628109	23554169	ASA	2	conceived and designed experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3628109	23554169	CF	2	conceived and designed experiments|wrote the manuscript	conceived and designed experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
3628109	23554169	CF	2	conceived and designed experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3628109	23554169	MH	2	gave comments on the manuscript	gave comments on the manuscript	-	-	NO
3628109	23554169	PJS	2	conceived and designed experiments|gave comments on the manuscript	conceived and designed experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
3628109	23554169	PJS	2	conceived and designed experiments|gave comments on the manuscript	gave comments on the manuscript	-	-	NO
3628109	23554169	RT	2	conceived and designed experiments|wrote the manuscript	conceived and designed experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
3628109	23554169	RT	2	conceived and designed experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3628109	23554169	SB	2	conceived and designed experiments|gave comments on the manuscript	conceived and designed experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
3628109	23554169	SB	2	conceived and designed experiments|gave comments on the manuscript	gave comments on the manuscript	-	-	NO
3628109	23554169	TP	2	gave comments on the manuscript	gave comments on the manuscript	-	-	NO
4418718	25938566	ADS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4418718	25938566	ADS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418718	25938566	CB	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418718	25938566	CB	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418718	25938566	CG	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418718	25938566	DS	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418718	25938566	GA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418718	25938566	GA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4418718	25938566	GA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418718	25938566	JF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418718	25938566	JF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418718	25938566	JF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418718	25938566	KG	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4418718	25938566	KG	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418718	25938566	MD	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4418718	25938566	MD	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418718	25938566	NM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418718	25938566	NM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418718	25938566	NM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418718	25938566	NM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418718	25938566	PA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418718	25938566	PA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4418718	25938566	PA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5566882	28808101	C.A.R.	2	conceived the study, designed experiments and revised the manuscript	conceived the study, designed experiments and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
5566882	28808101	C.A.S.	2	performed gene transformation and initial line selection and revised the manuscript	performed gene transformation and initial line selection and revised the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5566882	28808101	H.D.J.	2	performed gene transformation and initial line selection and revised the manuscript	performed gene transformation and initial line selection and revised the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5566882	28808101	M.A.J.P.	2	conceived the study, designed experiments and revised the manuscript	conceived the study, designed experiments and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
5566882	28808101	P.J.M.	2	designed and made the gene construct	designed and made the gene construct	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5566882	28808101	T.L.	2	conceived the study, designed experiments and revised the manuscript	conceived the study, designed experiments and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
5811972	29439663	JKW	2	conceived the idea and designed and instructed the study|wrote the manuscript	conceived the idea and designed and instructed the study	Conceived and designed the experiments	Conceptualization|Methodology|Supervision	YES
5811972	29439663	JKW	2	conceived the idea and designed and instructed the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5811972	29439663	JW	2	prepared all librabries and analyzed the data|wrote the manuscript	prepared all librabries and analyzed the data	Analyzed the data	Formal analysis	YES
5811972	29439663	JW	2	prepared all librabries and analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5811972	29439663	LW	2	prepared all adaptors and performed all pcr detection of clones and sequencing|also contibuted to the thorough reading and revision of the manuscript	prepared all adaptors and performed all pcr detection of clones and sequencing	Performed the experiments	Investigation	YES
5811972	29439663	LW	2	prepared all adaptors and performed all pcr detection of clones and sequencing|also contibuted to the thorough reading and revision of the manuscript	also contibuted to the thorough reading and revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5811972	29439663	WD	2	cultivated all cells and performed all tn5 tagmentations|also contibuted to the thorough reading and revision of the manuscript	cultivated all cells and performed all tn5 tagmentations	Performed the experiments	Investigation	YES
5811972	29439663	WD	2	cultivated all cells and performed all tn5 tagmentations|also contibuted to the thorough reading and revision of the manuscript	also contibuted to the thorough reading and revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5290656	28174662	AC	2	designed the study contributed to the interpretation of results and drafted the manuscript	designed the study contributed to the interpretation of results and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5290656	28174662	C-B	2	contributed to the design of the study, access to participants and drafting of the manuscript	contributed to the design of the study, access to participants and drafting of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5290656	28174662	LC	2	collected the data	collected the data	Performed the experiments	Investigation	YES
5290656	28174662	LP	2	substantially contributed to the data analysis and interpretation of results and helped draft the manuscript	substantially contributed to the data analysis and interpretation of results and helped draft the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5290656	28174662	OC	2	collected the data	collected the data	Performed the experiments	Investigation	YES
5290656	28174662	TV	2	designed the study contributed to the interpretation of results and drafted the manuscript	designed the study contributed to the interpretation of results and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5835031	29535744	All authors	2	have read and approved the final manuscript	have read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5835031	29535744	CC	2	participated in field trials and dna extraction	participated in field trials and dna extraction	Performed the experiments	Investigation	YES
5835031	29535744	DaL	2	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5835031	29535744	DeL	2	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5835031	29535744	JZ	2	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5835031	29535744	KG	2	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5835031	29535744	PY	2	participated in field trials and dna extraction	participated in field trials and dna extraction	Performed the experiments	Investigation	YES
5835031	29535744	QL	2	performed phenotyping data analysis	performed phenotyping data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5835031	29535744	WW	2	participated in field trials and dna extraction	participated in field trials and dna extraction	Performed the experiments	Investigation	YES
5835031	29535744	XL	2	participated in field trials and dna extraction	participated in field trials and dna extraction	Performed the experiments	Investigation	YES
5835031	29535744	XS	2	performed phenotyping data analysis	performed phenotyping data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5835031	29535744	YS	2	participated in field trials and dna extraction	participated in field trials and dna extraction	Performed the experiments	Investigation	YES
5835031	29535744	ZhaT	2	performed the experiments and drafted the manuscript|performed phenotyping data analysis	performed the experiments and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5835031	29535744	ZhaT	2	performed the experiments and drafted the manuscript|performed phenotyping data analysis	performed phenotyping data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5835031	29535744	ZheZ	2	designed and supervised the experiments and contributed final editing of manuscript	designed and supervised the experiments and contributed final editing of manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Review & Editing	YES
5835031	29535744	ZhoT	2	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
6270855	25264834	Pei Zhang	2	contributed with the performance of the experiments	contributed with the performance of the experiments	Performed the experiments	Investigation	YES
6270855	25264834	Pei Zhou	2	conducted the experimental design and revised the manuscript	conducted the experimental design and revised the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
6270855	25264834	Wei Zhou	2	carried out the experiment and prepared the manuscript	carried out the experiment and prepared the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6270855	25264834	Xiaohui Liu	2	contributed with the performance of the experiments	contributed with the performance of the experiments	Performed the experiments	Investigation	YES
6270855	25264834	Xunlong Shi	2	conducted the experimental design and revised the manuscript	conducted the experimental design and revised the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
2002513	17940605	AW	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
2002513	17940605	AW	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2002513	17940605	DM	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2002513	17940605	DM	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
2002513	17940605	GR	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2002513	17940605	GR	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2002513	17940605	LC	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2002513	17940605	LC	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2002513	17940605	SP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2002513	17940605	SP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2002513	17940605	SP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2002513	17940605	SP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2002513	17940605	SP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2002513	17940605	WN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2002513	17940605	WN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
2002513	17940605	WN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5984615	29858702	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5984615	29858702	JH	2	designed the work|performed the experiments and analyzed the data|wrote the manuscript	designed the work	Conceived and designed the experiments	-	YES
5984615	29858702	JH	2	designed the work|performed the experiments and analyzed the data|wrote the manuscript	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5984615	29858702	JH	2	designed the work|performed the experiments and analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5984615	29858702	QL	2	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5984615	29858702	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5984615	29858702	XW	2	performed the experiments and analyzed the data|wrote the manuscript	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5984615	29858702	XW	2	performed the experiments and analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5984615	29858702	YD	2	designed the work|reviewed and edited the manuscript	designed the work	Conceived and designed the experiments	-	YES
5984615	29858702	YD	2	designed the work|reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
4657081	26640803	Ping Xuan	2	contributed equally to this work	contributed equally to this work	-	-	NO
4657081	26640803	Yingli Zhong	2	contributed equally to this work	contributed equally to this work	-	-	NO
5566885	28808104	A.T.	2	performed epr experiments	performed epr experiments	Performed the experiments	Investigation	YES
5566885	28808104	E.-M.A.	2	devised the research|wrote the manuscript	devised the research	Conceived and designed the experiments	Conceptualization	YES
5566885	28808104	E.-M.A.	2	devised the research|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5566885	28808104	M.T.	2	devised the research|carried out the experiments and data analysis|wrote the manuscript	devised the research	Conceived and designed the experiments	Conceptualization	YES
5566885	28808104	M.T.	2	devised the research|carried out the experiments and data analysis|wrote the manuscript	carried out the experiments and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5566885	28808104	M.T.	2	devised the research|carried out the experiments and data analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5566885	28808104	P.J.G.	2	devised the research|carried out the experiments and data analysis|wrote the manuscript	devised the research	Conceived and designed the experiments	Conceptualization	YES
5566885	28808104	P.J.G.	2	devised the research|carried out the experiments and data analysis|wrote the manuscript	carried out the experiments and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5566885	28808104	P.J.G.	2	devised the research|carried out the experiments and data analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5566885	28808104	Y.L.-M.	2	carried out the experiments and data analysis|wrote the manuscript	carried out the experiments and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5566885	28808104	Y.L.-M.	2	carried out the experiments and data analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4418719	25938674	JL	PLoS5	Performed the experiments|Experimental technology center for life sciences	Performed the experiments	Performed the experiments	Investigation	YES
4418719	25938674	JL	PLoS5	Performed the experiments|Experimental technology center for life sciences	Experimental technology center for life sciences	-	-	NO
4418719	25938674	LZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418719	25938674	MXZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418719	25938674	MXZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4418719	25938674	MXZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418719	25938674	SJZ	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418719	25938674	SJZ	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418719	25938674	XBZ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4418719	25938674	XBZ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4418719	25938674	XBZ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418719	25938674	XHL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418719	25938674	XNC	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418719	25938674	XNC	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418719	25938674	XWZ	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4418719	25938674	XWZ	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5811979	29439658	DC	PLoS52	performed data analysis	performed data analysis	Analyzed the data	Formal analysis	YES
5811979	29439658	LP	PLoS52	designed the experiments|performed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5811979	29439658	LP	PLoS52	designed the experiments|performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5811979	29439658	OG	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5811979	29439658	SRQ	PLoS52	designed the experiments|interpreted the data and wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5811979	29439658	SRQ	PLoS52	designed the experiments|interpreted the data and wrote the manuscript	interpreted the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5811979	29439658	WW	PLoS52	designed the experiments|performed the experiments|performed data analysis|interpreted the data and wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5811979	29439658	WW	PLoS52	designed the experiments|performed the experiments|performed data analysis|interpreted the data and wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5811979	29439658	WW	PLoS52	designed the experiments|performed the experiments|performed data analysis|interpreted the data and wrote the manuscript	performed data analysis	Analyzed the data	Formal analysis	YES
5811979	29439658	WW	PLoS52	designed the experiments|performed the experiments|performed data analysis|interpreted the data and wrote the manuscript	interpreted the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
2002514	17940614	CB	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2002514	17940614	DN	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
2002514	17940614	DS	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2002514	17940614	FC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
2002514	17940614	GA	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2002514	17940614	JB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
2002514	17940614	JE	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the study|Enrolled patients	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2002514	17940614	JE	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the study|Enrolled patients	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2002514	17940614	JE	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the study|Enrolled patients	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2002514	17940614	JE	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the study|Enrolled patients	Designed the study	Conceived and designed the experiments	Methodology	YES
2002514	17940614	JE	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the study|Enrolled patients	Enrolled patients	Performed the experiments	Investigation	YES
2002514	17940614	KP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
2002514	17940614	MT	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2002514	17940614	NM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
2002514	17940614	OI	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2002514	17940614	RS	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2002514	17940614	SB	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2002514	17940614	SB	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2002514	17940614	SB	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2002514	17940614	YW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2002514	17940614	YW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2002514	17940614	YW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2002514	17940614	YW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2002514	17940614	YW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5835033	29535749	AC	7	Did the experimental design for the field experiments	Did the experimental design for the field experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5835033	29535749	DD	7	Designed and commissioned Phenomobile Lite|Wrote the manuscript with contributions from GR, RF, XS, WB, and RJ	Designed and commissioned Phenomobile Lite	Conceived and designed the experiments	-	YES
5835033	29535749	DD	7	Designed and commissioned Phenomobile Lite|Wrote the manuscript with contributions from GR, RF, XS, WB, and RJ	Wrote the manuscript with contributions from GR, RF, XS, WB, and RJ	Wrote the paper	Writing - Original Draft	YES
5835033	29535749	GR	7	Did the statistical analysis	Did the statistical analysis	Analyzed the data	Formal analysis	YES
5835033	29535749	JJ-B	7	Designed and commissioned Phenomobile Lite|Designed the lidar processing algorithms with input from RF and XS|Did the statistical analysis|Wrote the manuscript with contributions from GR, RF, XS, WB, and RJ	Designed and commissioned Phenomobile Lite	Conceived and designed the experiments	-	YES
5835033	29535749	JJ-B	7	Designed and commissioned Phenomobile Lite|Designed the lidar processing algorithms with input from RF and XS|Did the statistical analysis|Wrote the manuscript with contributions from GR, RF, XS, WB, and RJ	Designed the lidar processing algorithms with input from RF and XS	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
5835033	29535749	JJ-B	7	Designed and commissioned Phenomobile Lite|Designed the lidar processing algorithms with input from RF and XS|Did the statistical analysis|Wrote the manuscript with contributions from GR, RF, XS, WB, and RJ	Did the statistical analysis	Analyzed the data	Formal analysis	YES
5835033	29535749	JJ-B	7	Designed and commissioned Phenomobile Lite|Designed the lidar processing algorithms with input from RF and XS|Did the statistical analysis|Wrote the manuscript with contributions from GR, RF, XS, WB, and RJ	Wrote the manuscript with contributions from GR, RF, XS, WB, and RJ	Wrote the paper	Writing - Original Draft	YES
5835033	29535749	PR-L	7	Implemented the algorithms and processing pipeline with input from JJ-B	Implemented the algorithms and processing pipeline with input from JJ-B	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5835033	29535749	WB	7	Did the statistical analysis	Did the statistical analysis	Analyzed the data	Formal analysis	YES
5299760	28194277	AY	2	collected the data|performed the statistical analyses	collected the data	Performed the experiments	Investigation	YES
5299760	28194277	AY	2	collected the data|performed the statistical analyses	performed the statistical analyses	Analyzed the data	Formal analysis	YES
5299760	28194277	FA	2	designed the study and wrote the manuscript	designed the study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5299760	28194277	HM	2	collected the data	collected the data	Performed the experiments	Investigation	YES
5299760	28194277	MY	2	performed the statistical analyses	performed the statistical analyses	Analyzed the data	Formal analysis	YES
6270856	24492595	Charlotte Geny	2	contributed equally to this work	contributed equally to this work	-	-	NO
6270856	24492595	Mohamad Nurul Azmi	2	contributed equally to this work	contributed equally to this work	-	-	NO
5984946	29860613	All	PLoS52	data generated or analyzed during this study are included in the figures and tables	data generated or analyzed during this study are included in the figures and tables	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
5984946	29860613	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5984946	29860613	CJX	PLoS52	analyzed the data|polished the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5984946	29860613	CJX	PLoS52	analyzed the data|polished the paper	polished the paper	Wrote the paper	Writing - Review & Editing	YES
5984946	29860613	HH	PLoS52	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5984946	29860613	Innovative Research Teams	PLoS52	in universities of jiangsu province	in universities of jiangsu province	-	-	NO
5984946	29860613	Ivan Hajnal	PLoS52	for critical reading and editing of our manuscript	for critical reading and editing of our manuscript	Wrote the paper	Writing - Review & Editing	YES
5984946	29860613	JLX	PLoS52	performed the research	performed the research	Performed the experiments	Investigation	YES
5984946	29860613	LJ	PLoS52	designed the experiments|supervised the research|polished the paper	designed the experiments	Conceived and designed the experiments	Methodology	YES
5984946	29860613	LJ	PLoS52	designed the experiments|supervised the research|polished the paper	supervised the research	-	Supervision	YES
5984946	29860613	LJ	PLoS52	designed the experiments|supervised the research|polished the paper	polished the paper	Wrote the paper	Writing - Review & Editing	YES
5984946	29860613	LQT	PLoS52	performed the research	performed the research	Performed the experiments	Investigation	YES
5984946	29860613	The authors	PLoS52	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5984946	29860613	XX	PLoS52	performed the research|analyzed the data|wrote the paper	performed the research	Performed the experiments	Investigation	YES
5984946	29860613	XX	PLoS52	performed the research|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5984946	29860613	XX	PLoS52	performed the research|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5566886	28808105	B.K.	2	leading to the acquisition of data	leading to the acquisition of data	Performed the experiments	Investigation	YES
5566886	28808105	C.H.F.	2	conceived and designed the experiments and provided overall guidance for the work|conceived and designed the experiments and provided overall guidance for the work|drafted the article and revised it|drafted the article and revised it	conceived and designed the experiments and provided overall guidance for the work	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology|Supervision	YES
5566886	28808105	C.H.F.	2	conceived and designed the experiments and provided overall guidance for the work|conceived and designed the experiments and provided overall guidance for the work|drafted the article and revised it|drafted the article and revised it	conceived and designed the experiments and provided overall guidance for the work	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology|Supervision	YES
5566886	28808105	C.H.F.	2	conceived and designed the experiments and provided overall guidance for the work|conceived and designed the experiments and provided overall guidance for the work|drafted the article and revised it|drafted the article and revised it	drafted the article and revised it	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5566886	28808105	C.H.F.	2	conceived and designed the experiments and provided overall guidance for the work|conceived and designed the experiments and provided overall guidance for the work|drafted the article and revised it|drafted the article and revised it	drafted the article and revised it	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4418720	25938493	AM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418720	25938493	AM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418720	25938493	AM	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418720	25938493	DE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418720	25938493	DE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418720	25938493	DE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418720	25938493	DE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418720	25938493	DE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418720	25938493	DM	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418720	25938493	HF	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418720	25938493	HF	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418720	25938493	HF	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418720	25938493	JM	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418720	25938493	LM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418720	25938493	LM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418720	25938493	LM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418720	25938493	LM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418720	25938493	LM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418720	25938493	SK	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418720	25938493	SK	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4194396	25308848	VI	2	work plan projecting, operative research, results discussion and interpretation	work plan projecting, operative research, results discussion and interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4194396	25308848	VMP	2	supervision, work plan projecting, operative research, results discussion and interpretation	supervision, work plan projecting, operative research, results discussion and interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Supervision	YES
2002515	17940604	AA	1	Contributed to the conduct of the trial|Contributed to the revisions of the protocol and report	Contributed to the conduct of the trial	Performed the experiments	Investigation	YES
2002515	17940604	AA	1	Contributed to the conduct of the trial|Contributed to the revisions of the protocol and report	Contributed to the revisions of the protocol and report	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
2002515	17940604	AF	1	Contributed to the conduct of the trial|Contributed to the revisions of the protocol and report	Contributed to the conduct of the trial	Performed the experiments	Investigation	YES
2002515	17940604	AF	1	Contributed to the conduct of the trial|Contributed to the revisions of the protocol and report	Contributed to the revisions of the protocol and report	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
2002515	17940604	AO	1	Wrote the first draft of the protocol and the report|Had primary responsibility for the conduct of the trial	Wrote the first draft of the protocol and the report	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
2002515	17940604	AO	1	Wrote the first draft of the protocol and the report|Had primary responsibility for the conduct of the trial	Had primary responsibility for the conduct of the trial	Performed the experiments	Investigation	YES
2002515	17940604	BB	1	Contributed to the revisions of the protocol and report	Contributed to the revisions of the protocol and report	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
2002515	17940604	CC	1	Contributed to the conduct of the trial|Contributed to the revisions of the protocol and report	Contributed to the conduct of the trial	Performed the experiments	Investigation	YES
2002515	17940604	CC	1	Contributed to the conduct of the trial|Contributed to the revisions of the protocol and report	Contributed to the revisions of the protocol and report	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
2002515	17940604	JO	1	Conducted the statistical analyses|Contributed to the conduct of the trial|Contributed to the revisions of the protocol and report	Conducted the statistical analyses	Analyzed the data	Formal analysis	YES
2002515	17940604	JO	1	Conducted the statistical analyses|Contributed to the conduct of the trial|Contributed to the revisions of the protocol and report	Contributed to the conduct of the trial	Performed the experiments	Investigation	YES
2002515	17940604	JO	1	Conducted the statistical analyses|Contributed to the conduct of the trial|Contributed to the revisions of the protocol and report	Contributed to the revisions of the protocol and report	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
2002515	17940604	KH	1	Contributed to the conduct of the trial|Contributed to the revisions of the protocol and report	Contributed to the conduct of the trial	Performed the experiments	Investigation	YES
2002515	17940604	KH	1	Contributed to the conduct of the trial|Contributed to the revisions of the protocol and report	Contributed to the revisions of the protocol and report	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
2002515	17940604	SF	1	Contributed to the conduct of the trial|Contributed to the revisions of the protocol and report	Contributed to the conduct of the trial	Performed the experiments	Investigation	YES
2002515	17940604	SF	1	Contributed to the conduct of the trial|Contributed to the revisions of the protocol and report	Contributed to the revisions of the protocol and report	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
2002515	17940604	SP	1	Contributed to the revisions of the protocol and report	Contributed to the revisions of the protocol and report	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5316231	28239475	AVNM	2	contributed to acquisition of the data and interpretation of the results	contributed to acquisition of the data and interpretation of the results	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5316231	28239475	All	2	contributed to acquisition of the data and interpretation of the results	contributed to acquisition of the data and interpretation of the results	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5316231	28239475	DPR	2	was responsible for study design, acquisitions of the data, interpretation of the results, and revision of the manuscript for important intellectual content	was responsible for study design, acquisitions of the data, interpretation of the results, and revision of the manuscript for important intellectual content	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Review & Editing	YES
5316231	28239475	JRAA	2	was responsible for study design, data analysis, statistical analysis, and critical revision of the manuscript for important intellectual content	was responsible for study design, data analysis, statistical analysis, and critical revision of the manuscript for important intellectual content	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
5316231	28239475	MPP	2	contributed to the study design, coordination of data acquisition, interpretation of the data, and critical revision of the manuscript for important intellectual content	contributed to the study design, coordination of data acquisition, interpretation of the data, and critical revision of the manuscript for important intellectual content	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Project administration|Resources|Writing - Review & Editing	YES
5316231	28239475	PHCPP	2	contributed to acquisition of the data and interpretation of the result	contributed to acquisition of the data and interpretation of the result	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5316231	28239475	SCCS	2	contributed to the study design, acquisitions of the data, and interpretation of the results	contributed to the study design, acquisitions of the data, and interpretation of the results	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Methodology|Resources	YES
5316231	28239475	VFSA	2	contributed to acquisition of the data, interpretation of the results, and drafting of the manuscript	contributed to acquisition of the data, interpretation of the results, and drafting of the manuscript	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft	YES
5316231	28239475	WSM	2	was responsible for study design, data analysis, statistical analysis, and critical revision of the manuscript for important intellectual content	was responsible for study design, data analysis, statistical analysis, and critical revision of the manuscript for important intellectual content	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
3662312	23568409	AB	2	supervised the research	supervised the research	-	Supervision	YES
3662312	23568409	AF	2	designed research, supervised research and wrote the manuscript	designed research, supervised research and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Original Draft	YES
3662312	23568409	CM	2	performed research	performed research	Performed the experiments	Investigation	YES
3662312	23568409	CS	2	helped in mouse injections	helped in mouse injections	Performed the experiments	Investigation	YES
3662312	23568409	EDL	2	performed behavioural analysis	performed behavioural analysis	Performed the experiments	Investigation	YES
3662312	23568409	EN	2	maintained the mouse colony, performed mouse injections and processed tissues	maintained the mouse colony, performed mouse injections and processed tissues	Performed the experiments	Investigation	YES
3662312	23568409	EP	2	performed em analysis	performed em analysis	Performed the experiments	Investigation	YES
3662312	23568409	IS	2	contributed by performing co-localization experiments	contributed by performing co-localization experiments	Performed the experiments	Investigation	YES
3662312	23568409	LDO	2	maintained the mouse colony, performed mouse injections and processed tissues	maintained the mouse colony, performed mouse injections and processed tissues	Performed the experiments	Investigation	YES
3662312	23568409	NCS	2	performed research and analysed data	performed research and analysed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3662312	23568409	PS	2	performed behavioural analysis	performed behavioural analysis	Performed the experiments	Investigation	YES
5812216	29439649	ARP	PLoS5	Agree with manuscript results and conclusions|Made critical revisions and approved final version	Agree with manuscript results and conclusions	-	-	NO
5812216	29439649	ARP	PLoS5	Agree with manuscript results and conclusions|Made critical revisions and approved final version	Made critical revisions and approved final version	Wrote the paper	Writing - Review & Editing	YES
5812216	29439649	DEF	PLoS5	Conceived and designed the experiments|Agree with manuscript results and conclusions|Made critical revisions and approved final version	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5812216	29439649	DEF	PLoS5	Conceived and designed the experiments|Agree with manuscript results and conclusions|Made critical revisions and approved final version	Agree with manuscript results and conclusions	-	-	NO
5812216	29439649	DEF	PLoS5	Conceived and designed the experiments|Agree with manuscript results and conclusions|Made critical revisions and approved final version	Made critical revisions and approved final version	Wrote the paper	Writing - Review & Editing	YES
5812216	29439649	JAK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the first draft of the manuscript|Contributed to the writing of the manuscript|Agree with manuscript results and conclusions|Jointly developed the structure and arguments for the paper|Made critical revisions and approved final version	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5812216	29439649	JAK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the first draft of the manuscript|Contributed to the writing of the manuscript|Agree with manuscript results and conclusions|Jointly developed the structure and arguments for the paper|Made critical revisions and approved final version	Analyzed the data	Analyzed the data	Formal analysis	YES
5812216	29439649	JAK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the first draft of the manuscript|Contributed to the writing of the manuscript|Agree with manuscript results and conclusions|Jointly developed the structure and arguments for the paper|Made critical revisions and approved final version	Wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
5812216	29439649	JAK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the first draft of the manuscript|Contributed to the writing of the manuscript|Agree with manuscript results and conclusions|Jointly developed the structure and arguments for the paper|Made critical revisions and approved final version	Contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5812216	29439649	JAK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the first draft of the manuscript|Contributed to the writing of the manuscript|Agree with manuscript results and conclusions|Jointly developed the structure and arguments for the paper|Made critical revisions and approved final version	Agree with manuscript results and conclusions	-	-	NO
5812216	29439649	JAK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the first draft of the manuscript|Contributed to the writing of the manuscript|Agree with manuscript results and conclusions|Jointly developed the structure and arguments for the paper|Made critical revisions and approved final version	Jointly developed the structure and arguments for the paper	Wrote the paper	Writing - Original Draft	YES
5812216	29439649	JAK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the first draft of the manuscript|Contributed to the writing of the manuscript|Agree with manuscript results and conclusions|Jointly developed the structure and arguments for the paper|Made critical revisions and approved final version	Made critical revisions and approved final version	Wrote the paper	Writing - Review & Editing	YES
5812216	29439649	PSY	PLoS5	Conceived and designed the experiments|Contributed to the writing of the manuscript|Agree with manuscript results and conclusions|Jointly developed the structure and arguments for the paper|Made critical revisions and approved final version	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5812216	29439649	PSY	PLoS5	Conceived and designed the experiments|Contributed to the writing of the manuscript|Agree with manuscript results and conclusions|Jointly developed the structure and arguments for the paper|Made critical revisions and approved final version	Contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5812216	29439649	PSY	PLoS5	Conceived and designed the experiments|Contributed to the writing of the manuscript|Agree with manuscript results and conclusions|Jointly developed the structure and arguments for the paper|Made critical revisions and approved final version	Agree with manuscript results and conclusions	-	-	NO
5812216	29439649	PSY	PLoS5	Conceived and designed the experiments|Contributed to the writing of the manuscript|Agree with manuscript results and conclusions|Jointly developed the structure and arguments for the paper|Made critical revisions and approved final version	Jointly developed the structure and arguments for the paper	Wrote the paper	Writing - Original Draft	YES
5812216	29439649	PSY	PLoS5	Conceived and designed the experiments|Contributed to the writing of the manuscript|Agree with manuscript results and conclusions|Jointly developed the structure and arguments for the paper|Made critical revisions and approved final version	Made critical revisions and approved final version	Wrote the paper	Writing - Review & Editing	YES
5812216	29439649	RB	PLoS5	Conceived and designed the experiments|Contributed to the writing of the manuscript|Agree with manuscript results and conclusions|Jointly developed the structure and arguments for the paper|Made critical revisions and approved final version	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5812216	29439649	RB	PLoS5	Conceived and designed the experiments|Contributed to the writing of the manuscript|Agree with manuscript results and conclusions|Jointly developed the structure and arguments for the paper|Made critical revisions and approved final version	Contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5812216	29439649	RB	PLoS5	Conceived and designed the experiments|Contributed to the writing of the manuscript|Agree with manuscript results and conclusions|Jointly developed the structure and arguments for the paper|Made critical revisions and approved final version	Agree with manuscript results and conclusions	-	-	NO
5812216	29439649	RB	PLoS5	Conceived and designed the experiments|Contributed to the writing of the manuscript|Agree with manuscript results and conclusions|Jointly developed the structure and arguments for the paper|Made critical revisions and approved final version	Jointly developed the structure and arguments for the paper	Wrote the paper	Writing - Original Draft	YES
5812216	29439649	RB	PLoS5	Conceived and designed the experiments|Contributed to the writing of the manuscript|Agree with manuscript results and conclusions|Jointly developed the structure and arguments for the paper|Made critical revisions and approved final version	Made critical revisions and approved final version	Wrote the paper	Writing - Review & Editing	YES
5812216	29439649	TMT	PLoS5	Agree with manuscript results and conclusions|Made critical revisions and approved final version	Agree with manuscript results and conclusions	-	-	NO
5812216	29439649	TMT	PLoS5	Agree with manuscript results and conclusions|Made critical revisions and approved final version	Made critical revisions and approved final version	Wrote the paper	Writing - Review & Editing	YES
5835038	29535748	CB	PLoS52	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5835038	29535748	HY	PLoS52	conceived and designed the work|revised the manuscript	conceived and designed the work	Conceived and designed the experiments	Conceptualization	YES
5835038	29535748	HY	PLoS52	conceived and designed the work|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5835038	29535748	HZ	PLoS52	conceived and designed the work|analyzed the data and wrote the paper|revised the manuscript	conceived and designed the work	Conceived and designed the experiments	Conceptualization	YES
5835038	29535748	HZ	PLoS52	conceived and designed the work|analyzed the data and wrote the paper|revised the manuscript	analyzed the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5835038	29535748	HZ	PLoS52	conceived and designed the work|analyzed the data and wrote the paper|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5835038	29535748	LQ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5835038	29535748	MZ	PLoS52	performed the experiments|analyzed the data and wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5835038	29535748	MZ	PLoS52	performed the experiments|analyzed the data and wrote the paper	analyzed the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6270857	25501918	Lizhou Sun	2	designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
6270857	25501918	Mingsong Fan	2	performed the experimental work	performed the experimental work	Performed the experiments	Investigation	YES
6270857	25501918	Qing Zuo	2	designed the research|performed the experimental work	designed the research	Conceived and designed the experiments	Methodology	YES
6270857	25501918	Qing Zuo	2	designed the research|performed the experimental work	performed the experimental work	Performed the experiments	Investigation	YES
6270857	25501918	Shan Zou	2	performed the experimental work	performed the experimental work	Performed the experiments	Investigation	YES
6270857	25501918	Shiyun Huang	2	performed the experimental work	performed the experimental work	Performed the experiments	Investigation	YES
6270857	25501918	Xiang Yu	2	performed the experimental work	performed the experimental work	Performed the experiments	Investigation	YES
6270857	25501918	Yanfen Zou	2	designed the research|performed the experimental work|wrote the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
6270857	25501918	Yanfen Zou	2	designed the research|performed the experimental work|wrote the manuscript	performed the experimental work	Performed the experiments	Investigation	YES
6270857	25501918	Yanfen Zou	2	designed the research|performed the experimental work|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6270857	25501918	Ziyan Jiang	2	performed the experimental work	performed the experimental work	Performed the experiments	Investigation	YES
4194397	25308849	JW	2	experiments performing, data analysis, manuscript drafting	experiments performing, data analysis, manuscript drafting	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4194397	25308849	MX	2	study design and supervision, manuscript revising	study design and supervision, manuscript revising	Conceived and designed the experiments	Methodology|Supervision	YES
4194397	25308849	QW	2	study design and supervision, manuscript revising	study design and supervision, manuscript revising	Conceived and designed the experiments	Methodology|Supervision	YES
4194397	25308849	SH	2	sample collection and experiments assistance, participation in manuscript revising	sample collection and experiments assistance, participation in manuscript revising	Performed the experiments	Investigation	YES
4194397	25308849	XS	2	sample collection and experiments assistance, participation in manuscript revising	sample collection and experiments assistance, participation in manuscript revising	Performed the experiments	Investigation	YES
4194397	25308849	YH	2	sample collection and experiments assistance, participation in manuscript revising	sample collection and experiments assistance, participation in manuscript revising	Performed the experiments	Investigation	YES
4194397	25308849	YL	2	experiments performing, data analysis, manuscript drafting	experiments performing, data analysis, manuscript drafting	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4194397	25308849	YS	2	sample collection and experiments assistance, participation in manuscript revising	sample collection and experiments assistance, participation in manuscript revising	Performed the experiments	Investigation	YES
4418721	25938772	CY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418721	25938772	CY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4418721	25938772	CY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418721	25938772	DT	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418721	25938772	JQ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418721	25938772	JQ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418721	25938772	JQ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418721	25938772	KH	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4418721	25938772	KH	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418721	25938772	LM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418721	25938772	LM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4418721	25938772	LM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418721	25938772	XL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4418721	25938772	XL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418721	25938772	YH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418721	25938772	YH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418721	25938772	YH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418721	25938772	YH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418721	25938772	YW	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5319036	28239476	KM	2	planned and conducted the study, collected the data, and drafted the manuscript	planned and conducted the study, collected the data, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
5319036	28239476	SK	2	helped to draft the manuscript	helped to draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5319036	28239476	YK	2	helped to plan the study and draft the manuscript	helped to plan the study and draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5988928	29873028	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5988928	29873028	BY	2	analyzed the data and wrote the paper	analyzed the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5988928	29873028	JG	2	designed the research|analyzed the data and wrote the paper	designed the research	Conceived and designed the experiments	Methodology	YES
5988928	29873028	JG	2	designed the research|analyzed the data and wrote the paper	analyzed the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5988928	29873028	MG	2	analyzed the data and wrote the paper	analyzed the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5988928	29873028	RM	2	performed the research	performed the research	Performed the experiments	Investigation	YES
5988928	29873028	SL	2	performed the research	performed the research	Performed the experiments	Investigation	YES
5988928	29873028	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5988928	29873028	YB	2	designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
5988928	29873028	YW	2	designed the research|performed the research|analyzed the data and wrote the paper	designed the research	Conceived and designed the experiments	Methodology	YES
5988928	29873028	YW	2	designed the research|performed the research|analyzed the data and wrote the paper	performed the research	Performed the experiments	Investigation	YES
5988928	29873028	YW	2	designed the research|performed the research|analyzed the data and wrote the paper	analyzed the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3662313	23606558	AB	2	designed and analysed the experiments and contributed to the writing of the paper	designed and analysed the experiments and contributed to the writing of the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3662313	23606558	CS	2	generated vectors, performed intramuscular studies, and interpreted data	generated vectors, performed intramuscular studies, and interpreted data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3662313	23606558	EF	2	performed tissue culture and live muscle fibre experiments, and analysed the data|designed the quantitative analysis of the live fibre data and participated in writing and preparation of the manuscript	performed tissue culture and live muscle fibre experiments, and analysed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3662313	23606558	EF	2	performed tissue culture and live muscle fibre experiments, and analysed the data|designed the quantitative analysis of the live fibre data and participated in writing and preparation of the manuscript	designed the quantitative analysis of the live fibre data and participated in writing and preparation of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3662313	23606558	FA	2	generated vectors, performed intramuscular studies, and interpreted data	generated vectors, performed intramuscular studies, and interpreted data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3662313	23606558	GP	2	designed and analysed the experiments and contributed to the writing of the paper	designed and analysed the experiments and contributed to the writing of the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3662313	23606558	HZ	2	performed statistical analysis and interpreted data	performed statistical analysis and interpreted data	Analyzed the data	Formal analysis	YES
3662313	23606558	JL	2	performed tissue culture and live muscle fibre experiments, and analysed the data	performed tissue culture and live muscle fibre experiments, and analysed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3662313	23606558	LL	2	performed tissue culture and live muscle fibre experiments, and analysed the data	performed tissue culture and live muscle fibre experiments, and analysed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3662313	23606558	MC	2	performed the biochemical and histological analyses of intramuscular studies	performed the biochemical and histological analyses of intramuscular studies	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3662313	23606558	NR	2	performed tissue culture and live muscle fibre experiments, and analysed the data|designed and analysed the experiments and wrote the paper	performed tissue culture and live muscle fibre experiments, and analysed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3662313	23606558	NR	2	performed tissue culture and live muscle fibre experiments, and analysed the data|designed and analysed the experiments and wrote the paper	designed and analysed the experiments and wrote the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3662313	23606558	RPo	2	performed the electron microscopy analysis	performed the electron microscopy analysis	Performed the experiments	Investigation	YES
3662313	23606558	RPu	2	contributed new reagents and analytical tools, interpreted and analysed data	contributed new reagents and analytical tools, interpreted and analysed data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5835042	29535741	A. All	PLoS52	authors reviewed the manuscript	authors reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5835042	29535741	AL	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5835042	29535741	CA	PLoS52	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5835042	29535741	CT-D	PLoS52	designed the experiments|analyzed the data	designed the experiments	Conceived and designed the experiments	Methodology	YES
5835042	29535741	CT-D	PLoS52	designed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5835042	29535741	IA-R	PLoS52	designed the experiments|analyzed the data	designed the experiments	Conceived and designed the experiments	Methodology	YES
5835042	29535741	IA-R	PLoS52	designed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5835042	29535741	MM-M	PLoS52	designed the experiments|performed the experiments|analyzed the data	designed the experiments	Conceived and designed the experiments	Methodology	YES
5835042	29535741	MM-M	PLoS52	designed the experiments|performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5835042	29535741	MM-M	PLoS52	designed the experiments|performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5835042	29535741	RH	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5835042	29535741	RH	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5835042	29535741	TF	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5835042	29535741	TF	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
2002516	17940606	AG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2002516	17940606	AG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2002516	17940606	AG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2002516	17940606	AG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2002516	17940606	CB	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2002516	17940606	CB	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2002516	17940606	PP	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2002516	17940606	PP	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2002516	17940606	PP	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270858	24743934	M.H.	2	designed the manuscript and significantly participated in its writing	designed the manuscript and significantly participated in its writing	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
6270858	24743934	M.P.	2	designed the manuscript and significantly participated in its writing	designed the manuscript and significantly participated in its writing	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
5812220	29439661	AA	2	sample collection and data processing	sample collection and data processing	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5812220	29439661	DR	2	performed the data analysis and interpreted results|participated in discussing and revising the manuscript	performed the data analysis and interpreted results	Analyzed the data	Formal analysis	YES
5812220	29439661	DR	2	performed the data analysis and interpreted results|participated in discussing and revising the manuscript	participated in discussing and revising the manuscript	Wrote the paper	Writing - Review & Editing	YES
5812220	29439661	GG	2	participated in discussing and revising the manuscript	participated in discussing and revising the manuscript	Wrote the paper	Writing - Review & Editing	YES
5812220	29439661	HC	2	project design and support|sample collection and data processing|performed the data analysis and interpreted results|drafted the manuscript	project design and support	Conceived and designed the experiments	Methodology	YES
5812220	29439661	HC	2	project design and support|sample collection and data processing|performed the data analysis and interpreted results|drafted the manuscript	sample collection and data processing	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5812220	29439661	HC	2	project design and support|sample collection and data processing|performed the data analysis and interpreted results|drafted the manuscript	performed the data analysis and interpreted results	Analyzed the data	Formal analysis	YES
5812220	29439661	HC	2	project design and support|sample collection and data processing|performed the data analysis and interpreted results|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5812220	29439661	IA	2	participated in discussing and revising the manuscript	participated in discussing and revising the manuscript	Wrote the paper	Writing - Review & Editing	YES
5812220	29439661	JN	2	sample collection and data processing|participated in discussing and revising the manuscript	sample collection and data processing	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5812220	29439661	JN	2	sample collection and data processing|participated in discussing and revising the manuscript	participated in discussing and revising the manuscript	Wrote the paper	Writing - Review & Editing	YES
5812220	29439661	KT	2	project design and support|participated in discussing and revising the manuscript	project design and support	Conceived and designed the experiments	Methodology	YES
5812220	29439661	KT	2	project design and support|participated in discussing and revising the manuscript	participated in discussing and revising the manuscript	Wrote the paper	Writing - Review & Editing	YES
5812220	29439661	MB	2	performed the data analysis and interpreted results|participated in discussing and revising the manuscript	performed the data analysis and interpreted results	Analyzed the data	Formal analysis	YES
5812220	29439661	MB	2	performed the data analysis and interpreted results|participated in discussing and revising the manuscript	participated in discussing and revising the manuscript	Wrote the paper	Writing - Review & Editing	YES
5812220	29439661	MM	2	project design and support|drafted the manuscript	project design and support	Conceived and designed the experiments	Methodology	YES
5812220	29439661	MM	2	project design and support|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5812220	29439661	MP	2	project design and support|participated in discussing and revising the manuscript	project design and support	Conceived and designed the experiments	Methodology	YES
5812220	29439661	MP	2	project design and support|participated in discussing and revising the manuscript	participated in discussing and revising the manuscript	Wrote the paper	Writing - Review & Editing	YES
5812220	29439661	MR	2	sample collection and data processing|participated in discussing and revising the manuscript	sample collection and data processing	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5812220	29439661	MR	2	sample collection and data processing|participated in discussing and revising the manuscript	participated in discussing and revising the manuscript	Wrote the paper	Writing - Review & Editing	YES
4418722	25938684	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418722	25938684	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418722	25938684	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418722	25938684	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418722	25938684	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4194398	25308850	All authors	2	have made substantial intellectual contributions to the conception and design of the study, data acquisition, analysis and interpretation and contributed to data interpretation and manuscript preparation	have made substantial intellectual contributions to the conception and design of the study, data acquisition, analysis and interpretation and contributed to data interpretation and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
4194398	25308850	DT	2	manuscript discussing and proofreading	manuscript discussing and proofreading	-	-	NO
4194398	25308850	GM	2	study design conception, manuscript writing and planning, results discussing and supervision	study design conception, manuscript writing and planning, results discussing and supervision	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Supervision|Writing - Original Draft	YES
4194398	25308850	LM	2	manuscript discussing and proofreading	manuscript discussing and proofreading	-	-	NO
4194398	25308850	MAS	2	contribution to data collection, technical assistance, interpretation and analysis	contribution to data collection, technical assistance, interpretation and analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
4194398	25308850	MD	2	experimental work, study execution and manuscript writing	experimental work, study execution and manuscript writing	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4657091	26640795	All authors	2	reviewed the paper	reviewed the paper	Wrote the paper	Writing - Review & Editing	YES
4657091	26640795	Cheng Han	2	carried out the study|wrote the main paper|contributed equally to this work	carried out the study	Performed the experiments	Investigation	YES
4657091	26640795	Cheng Han	2	carried out the study|wrote the main paper|contributed equally to this work	wrote the main paper	Wrote the paper	Writing - Original Draft	YES
4657091	26640795	Cheng Han	2	carried out the study|wrote the main paper|contributed equally to this work	contributed equally to this work	-	-	NO
4657091	26640795	Di Wu	2	wrote the main paper	wrote the main paper	Wrote the paper	Writing - Original Draft	YES
4657091	26640795	Haixia Guan	2	designed and funded the study	designed and funded the study	Conceived and designed the experiments	Funding acquisition|Methodology	YES
4657091	26640795	Jianqiu Gu	2	prepared the figures and tables	prepared the figures and tables	-	Visualization	YES
4657091	26640795	Rui Liu	2	carried out the study|wrote the main paper|contributed equally to this work	carried out the study	Performed the experiments	Investigation	YES
4657091	26640795	Rui Liu	2	carried out the study|wrote the main paper|contributed equally to this work	wrote the main paper	Wrote the paper	Writing - Original Draft	YES
4657091	26640795	Rui Liu	2	carried out the study|wrote the main paper|contributed equally to this work	contributed equally to this work	-	-	NO
4657091	26640795	Weiping Teng	2	designed and funded the study	designed and funded the study	Conceived and designed the experiments	Funding acquisition|Methodology	YES
4657091	26640795	Xinghai Xia	2	prepared the figures and tables	prepared the figures and tables	-	Visualization	YES
4657091	26640795	Zhongyan Shan	2	revised the paper	revised the paper	Wrote the paper	Writing - Review & Editing	YES
5566888	28808107	A.K.	2	contributed to the acquisition of data	contributed to the acquisition of data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5566888	28808107	All authors	2	were involved in the design, analysis and interpretation of the data and the drafting of the article	were involved in the design, analysis and interpretation of the data and the drafting of the article	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5566888	28808107	J.K.	2	contributed to the acquisition of data	contributed to the acquisition of data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5566888	28808107	J.W.M.	2	contributed to the acquisition of data	contributed to the acquisition of data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5566888	28808107	J.Y.	2	contributed to the acquisition of data	contributed to the acquisition of data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5566888	28808107	M.B.	2	contributed to the acquisition of data	contributed to the acquisition of data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5566888	28808107	S.S.	2	contributed to the acquisition of data	contributed to the acquisition of data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5566888	28808107	V.K.	2	contributed to the acquisition of data	contributed to the acquisition of data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
5324259	28250933	AW	PLoS52	collected and generated the data|analysed the data	collected and generated the data	Performed the experiments	Investigation	YES
5324259	28250933	AW	PLoS52	collected and generated the data|analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
5324259	28250933	DS	PLoS52	collected and generated the data|helped to draft the manuscript	collected and generated the data	Performed the experiments	Investigation	YES
5324259	28250933	DS	PLoS52	collected and generated the data|helped to draft the manuscript	helped to draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5324259	28250933	MO	PLoS52	designed the study|analysed the data|helped to draft the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5324259	28250933	MO	PLoS52	designed the study|analysed the data|helped to draft the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
5324259	28250933	MO	PLoS52	designed the study|analysed the data|helped to draft the manuscript	helped to draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5324259	28250933	NE	PLoS52	designed the study|collected and generated the data|analysed the data|wrote the first draft	designed the study	Conceived and designed the experiments	Methodology	YES
5324259	28250933	NE	PLoS52	designed the study|collected and generated the data|analysed the data|wrote the first draft	collected and generated the data	Performed the experiments	Investigation	YES
5324259	28250933	NE	PLoS52	designed the study|collected and generated the data|analysed the data|wrote the first draft	analysed the data	Analyzed the data	Formal analysis	YES
5324259	28250933	NE	PLoS52	designed the study|collected and generated the data|analysed the data|wrote the first draft	wrote the first draft	Wrote the paper	Writing - Original Draft	YES
5324259	28250933	NM	PLoS52	analysed the data|helped to draft the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
5324259	28250933	NM	PLoS52	analysed the data|helped to draft the manuscript	helped to draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5324259	28250933	TH	PLoS52	designed the study|analysed the data|wrote the first draft	designed the study	Conceived and designed the experiments	Methodology	YES
5324259	28250933	TH	PLoS52	designed the study|analysed the data|wrote the first draft	analysed the data	Analyzed the data	Formal analysis	YES
5324259	28250933	TH	PLoS52	designed the study|analysed the data|wrote the first draft	wrote the first draft	Wrote the paper	Writing - Original Draft	YES
5324259	28250933	TN	PLoS52	collected and generated the data|analysed the data	collected and generated the data	Performed the experiments	Investigation	YES
5324259	28250933	TN	PLoS52	collected and generated the data|analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
5324259	28250933	TS	PLoS52	designed the study|analysed the data|helped to draft the manuscript|helped to draft the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5324259	28250933	TS	PLoS52	designed the study|analysed the data|helped to draft the manuscript|helped to draft the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
5324259	28250933	TS	PLoS52	designed the study|analysed the data|helped to draft the manuscript|helped to draft the manuscript	helped to draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5324259	28250933	TS	PLoS52	designed the study|analysed the data|helped to draft the manuscript|helped to draft the manuscript	helped to draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5997607	29896640	AO	PLoS52	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5997607	29896640	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5997607	29896640	CHEN	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5997607	29896640	HE	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5997607	29896640	LI	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5997607	29896640	LIU	PLoS52	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5997607	29896640	WU	PLoS52	reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5997607	29896640	YU	PLoS52	performed the experiments|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5997607	29896640	YU	PLoS52	performed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5997607	29896640	ZHANG	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5997607	29896640	ZHOU	PLoS52	reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5997607	29896640	ZOU	PLoS52	provided the sample of fermented beans	provided the sample of fermented beans	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
2013936	17957239	AC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2013936	17957239	AC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2013936	17957239	AC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2013936	17957239	AM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2013936	17957239	AM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2013936	17957239	AM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2013936	17957239	AM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2013936	17957239	FB	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2013936	17957239	FB	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2013936	17957239	FB	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2013936	17957239	FB	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2013936	17957239	GP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2013936	17957239	GP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2013936	17957239	GP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2013936	17957239	GP	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2013936	17957239	LG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2013936	17957239	LG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2013936	17957239	LG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2013936	17957239	PS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2013936	17957239	PS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2013936	17957239	PS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2013936	17957239	PS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2013936	17957239	SF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2013936	17957239	SF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2013936	17957239	SF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2013936	17957239	SF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2013936	17957239	SF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2013936	17957239	TV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2013936	17957239	TV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2013936	17957239	TV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2013936	17957239	TV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3662314	23610071	AC	PLoS52	analysed the data and provided important intellectual content and advices in drafting and/or critically revising the article	analysed the data and provided important intellectual content and advices in drafting and/or critically revising the article	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
3662314	23610071	ADA	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
3662314	23610071	BB	PLoS52	analysed the data and wrote the paper|analysed the data and provided important intellectual content and advices in drafting and/or critically revising the article	analysed the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3662314	23610071	BB	PLoS52	analysed the data and wrote the paper|analysed the data and provided important intellectual content and advices in drafting and/or critically revising the article	analysed the data and provided important intellectual content and advices in drafting and/or critically revising the article	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
3662314	23610071	BP	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
3662314	23610071	BV	PLoS52	provided patients data and ihc analysis	provided patients data and ihc analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
3662314	23610071	DM	PLoS52	analysed the data and provided important intellectual content and advices in drafting and/or critically revising the article|provided patients data and ihc analysis	analysed the data and provided important intellectual content and advices in drafting and/or critically revising the article	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
3662314	23610071	DM	PLoS52	analysed the data and provided important intellectual content and advices in drafting and/or critically revising the article|provided patients data and ihc analysis	provided patients data and ihc analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
3662314	23610071	FL	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
3662314	23610071	GB	PLoS52	conceived and design the project|analysed the data and wrote the paper	conceived and design the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
3662314	23610071	GB	PLoS52	conceived and design the project|analysed the data and wrote the paper	analysed the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3662314	23610071	GDS	PLoS52	contributed new reagents/analytic tools|analysed the data and provided important intellectual content and advices in drafting and/or critically revising the article	contributed new reagents/analytic tools	Contributed reagents/materials/analysis tools	Resources	YES
3662314	23610071	GDS	PLoS52	contributed new reagents/analytic tools|analysed the data and provided important intellectual content and advices in drafting and/or critically revising the article	analysed the data and provided important intellectual content and advices in drafting and/or critically revising the article	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
3662314	23610071	GG	PLoS52	provided patients data and ihc analysis	provided patients data and ihc analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
3662314	23610071	LM	PLoS52	provided patients data and ihc analysis	provided patients data and ihc analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
3662314	23610071	MBag	PLoS52	provided patients data and ihc analysis	provided patients data and ihc analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
3662314	23610071	MBar	PLoS52	provided patients data and ihc analysis	provided patients data and ihc analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
3662314	23610071	ML	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
3662314	23610071	MN	PLoS52	contributed new reagents/analytic tools	contributed new reagents/analytic tools	Contributed reagents/materials/analysis tools	Resources	YES
3662314	23610071	MSc	PLoS52	analysed the data and wrote the paper|performed the experiments	analysed the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3662314	23610071	MSc	PLoS52	analysed the data and wrote the paper|performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
3662314	23610071	MSo	PLoS52	analysed the data and wrote the paper|performed the experiments	analysed the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3662314	23610071	MSo	PLoS52	analysed the data and wrote the paper|performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
3662314	23610071	SC	PLoS52	analysed the data and provided important intellectual content and advices in drafting and/or critically revising the article|provided patients data and ihc analysis	analysed the data and provided important intellectual content and advices in drafting and/or critically revising the article	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
3662314	23610071	SC	PLoS52	analysed the data and provided important intellectual content and advices in drafting and/or critically revising the article|provided patients data and ihc analysis	provided patients data and ihc analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
3662314	23610071	SDA	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
3662314	23610071	SL	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
3662314	23610071	VC	PLoS52	provided patients data and ihc analysis	provided patients data and ihc analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5835075	29535758	AW	2	carried out the experiment	carried out the experiment	Performed the experiments	Investigation	YES
5835075	29535758	DM	2	helped to revise the manuscript	helped to revise the manuscript	Wrote the paper	Writing - Review & Editing	YES
5835075	29535758	JS	2	conceived and designed the experiment|wrote the manuscript	conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5835075	29535758	JS	2	conceived and designed the experiment|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5835075	29535758	MK	2	offered the plant material	offered the plant material	Performed the experiments	Investigation	YES
5835075	29535758	MZ	2	helped to revise the manuscript	helped to revise the manuscript	Wrote the paper	Writing - Review & Editing	YES
5835075	29535758	TX	2	helped to revise the manuscript	helped to revise the manuscript	Wrote the paper	Writing - Review & Editing	YES
5835075	29535758	WW	2	offered the technological support on lipidomics	offered the technological support on lipidomics	Performed the experiments	Investigation	YES
5835075	29535758	XC	2	offered the technological support on lipidomics	offered the technological support on lipidomics	Performed the experiments	Investigation	YES
5835075	29535758	XL	2	carried out the experiment	carried out the experiment	Performed the experiments	Investigation	YES
5835075	29535758	YY	2	carried out the experiment	carried out the experiment	Performed the experiments	Investigation	YES
5835075	29535758	ZL	2	conceived and designed the experiment|helped to revise the manuscript	conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5835075	29535758	ZL	2	conceived and designed the experiment|helped to revise the manuscript	helped to revise the manuscript	Wrote the paper	Writing - Review & Editing	YES
6270859	25514052	BB	PLoS52	performed research and analyzed the data	performed research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270859	25514052	MP	PLoS52	performed research and analyzed the data|wrote the paper	performed research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270859	25514052	MP	PLoS52	performed research and analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5813327	29444661	KN	2	conceived and designed the software|drafted the manuscript	conceived and designed the software	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceptualization|Software	YES
5813327	29444661	KN	2	conceived and designed the software|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5813327	29444661	QZ	2	conceived and designed the software|conducted the experiments and analysis|drafted the manuscript	conceived and designed the software	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceptualization|Software	YES
5813327	29444661	QZ	2	conceived and designed the software|conducted the experiments and analysis|drafted the manuscript	conducted the experiments and analysis	Performed the experiments	Investigation	YES
5813327	29444661	QZ	2	conceived and designed the software|conducted the experiments and analysis|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5813327	29444661	SC	2	conceived and designed the software	conceived and designed the software	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceptualization|Software	YES
5813327	29444661	XS	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4418723	25938460	DJK	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4418723	25938460	DJK	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4418723	25938460	DJK	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418723	25938460	MF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418723	25938460	MF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418723	25938460	MF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418723	25938460	MF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418723	25938460	PMB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418723	25938460	PMB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418723	25938460	PMB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418723	25938460	PMB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418723	25938460	REM	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4418723	25938460	REM	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5835088	29535750	BS	2	contributed the materials or analytical tools	contributed the materials or analytical tools	Contributed reagents/materials/analysis tools	Resources	YES
5835088	29535750	HT	2	designed the partial research and revised the manuscript	designed the partial research and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5835088	29535750	JZ	2	designed this research, performed the experiments, analyzed the data, and wrote the manuscript	designed this research, performed the experiments, analyzed the data, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5835088	29535750	QC	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5835088	29535750	TC	2	designed the partial research and revised the manuscript	designed the partial research and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5835088	29535750	XW	2	designed this research and revised the manuscript	designed this research and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5835088	29535750	YL	2	contributed the materials or analytical tools	contributed the materials or analytical tools	Contributed reagents/materials/analysis tools	Resources	YES
5835088	29535750	YW	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5835088	29535750	YZ	2	contributed the materials or analytical tools	contributed the materials or analytical tools	Contributed reagents/materials/analysis tools	Resources	YES
5327570	28261486	ABD	PLoS52	designed the research|performed the research	designed the research	Conceived and designed the experiments	Methodology	YES
5327570	28261486	ABD	PLoS52	designed the research|performed the research	performed the research	Performed the experiments	Investigation	YES
5327570	28261486	AC	PLoS52	designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
5327570	28261486	BCH	PLoS52	designed the research|performed the research|analyzed the data|wrote the paper, and all authors contributed to revising the paper	designed the research	Conceived and designed the experiments	Methodology	YES
5327570	28261486	BCH	PLoS52	designed the research|performed the research|analyzed the data|wrote the paper, and all authors contributed to revising the paper	performed the research	Performed the experiments	Investigation	YES
5327570	28261486	BCH	PLoS52	designed the research|performed the research|analyzed the data|wrote the paper, and all authors contributed to revising the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5327570	28261486	BCH	PLoS52	designed the research|performed the research|analyzed the data|wrote the paper, and all authors contributed to revising the paper	wrote the paper, and all authors contributed to revising the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5327570	28261486	CL	PLoS52	made the mouse-human chimeric anti-porcine cd14 igg2/4 antibody	made the mouse-human chimeric anti-porcine cd14 igg2/4 antibody	Performed the experiments	Investigation	YES
5327570	28261486	DC	PLoS52	performed the laboratory analysis	performed the laboratory analysis	Performed the experiments	Investigation	YES
5327570	28261486	EWN	PLoS52	designed the research|performed the research	designed the research	Conceived and designed the experiments	Methodology	YES
5327570	28261486	EWN	PLoS52	designed the research|performed the research	performed the research	Performed the experiments	Investigation	YES
5327570	28261486	GB	PLoS52	performed the laboratory analysis	performed the laboratory analysis	Performed the experiments	Investigation	YES
5327570	28261486	HF	PLoS52	performed the laboratory analysis	performed the laboratory analysis	Performed the experiments	Investigation	YES
5327570	28261486	HLO	PLoS52	designed the research|performed the research	designed the research	Conceived and designed the experiments	Methodology	YES
5327570	28261486	HLO	PLoS52	designed the research|performed the research	performed the research	Performed the experiments	Investigation	YES
5327570	28261486	KD	PLoS52	performed the research	performed the research	Performed the experiments	Investigation	YES
5327570	28261486	MAN	PLoS52	supplied the coversin	supplied the coversin	Contributed reagents/materials/analysis tools	Resources	YES
5327570	28261486	PB	PLoS52	designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
5327570	28261486	SP	PLoS52	designed the research|performed the research	designed the research	Conceived and designed the experiments	Methodology	YES
5327570	28261486	SP	PLoS52	designed the research|performed the research	performed the research	Performed the experiments	Investigation	YES
5327570	28261486	TE	PLoS52	designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
5327570	28261486	TEM	PLoS52	designed the research|analyzed the data	designed the research	Conceived and designed the experiments	Methodology	YES
5327570	28261486	TEM	PLoS52	designed the research|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
3662315	23606532	BMS	2	conducted all experiments and all were involved in data interpretation	conducted all experiments and all were involved in data interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3662315	23606532	HYC	2	conducted all experiments and all were involved in data interpretation	conducted all experiments and all were involved in data interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3662315	23606532	MN	2	supervised the research and data interpretation	supervised the research and data interpretation	Analyzed the data	Formal analysis|Supervision	YES
3662315	23606532	YMY	2	conducted all experiments and all were involved in data interpretation	conducted all experiments and all were involved in data interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4418724	25938838	BWK	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418724	25938838	BWK	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418724	25938838	CT	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418724	25938838	CT	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418724	25938838	EOY	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4418724	25938838	EOY	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418724	25938838	FC	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418724	25938838	FC	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418724	25938838	FEC	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418724	25938838	FEC	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418724	25938838	IMK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4418724	25938838	IMK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418724	25938838	M. Cansev	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418724	25938838	M. Cansev	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418724	25938838	M. Cansev	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418724	25938838	M. Cansev	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418724	25938838	M. Cansev	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418724	25938838	M. Cetinkaya	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418724	25938838	M. Cetinkaya	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418724	25938838	SUS	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5566889	28808108	All authors	PLoS52	gave final approval for publication	gave final approval for publication	-	-	NO
5566889	28808108	E.R.	PLoS52	designed the review|wrote the paper	designed the review	Conceived and designed the experiments	-	YES
5566889	28808108	E.R.	PLoS52	designed the review|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5566889	28808108	J.T.	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5566889	28808108	L.N.	PLoS52	made the figure|wrote the paper	made the figure	-	Visualization	YES
5566889	28808108	L.N.	PLoS52	made the figure|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5566889	28808108	M.G.D.	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5997608	29896682	All authors	2	have contributed to this research work|read and approved the final manuscript	have contributed to this research work	Performed the experiments	Investigation	YES
5997608	29896682	All authors	2	have contributed to this research work|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5997608	29896682	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
4657382	26640785	Jing-Xin Zhao	2	have contributed equally to this work	have contributed equally to this work	-	-	NO
4657382	26640785	Xiu-Yun Su	2	have contributed equally to this work	have contributed equally to this work	-	-	NO
4657382	26640785	Zhe Zhao	2	have contributed equally to this work	have contributed equally to this work	-	-	NO
5835114	29535754	Both authors	2	contributed critically to manuscript preparation	contributed critically to manuscript preparation	Wrote the paper	Writing - Original Draft	YES
5835114	29535754	DG	2	assembled data from the literature and assisted in data analysis	assembled data from the literature and assisted in data analysis	Analyzed the data	Formal analysis	YES
5835114	29535754	JVS	2	conceived the study and supervised the literature synthesis and analysis	conceived the study and supervised the literature synthesis and analysis	Conceived and designed the experiments	Conceptualization|Supervision	YES
5813380	29444639	ACan	PLoS52	designed the experiment|wrote the paper	designed the experiment	Conceived and designed the experiments	Methodology	YES
5813380	29444639	ACan	PLoS52	designed the experiment|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5813380	29444639	ACas	PLoS52	designed the rt-qpcr experiments|analysed the rt-qpcr data	designed the rt-qpcr experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5813380	29444639	ACas	PLoS52	designed the rt-qpcr experiments|analysed the rt-qpcr data	analysed the rt-qpcr data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5813380	29444639	MA	PLoS52	designed the experiment|wrote the paper	designed the experiment	Conceived and designed the experiments	Methodology	YES
5813380	29444639	MA	PLoS52	designed the experiment|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5813380	29444639	RGP	PLoS52	performed rna extractions	performed rna extractions	Performed the experiments	Investigation	YES
5813380	29444639	RQ	PLoS52	designed the experiment|was responsible for the experimental protocols and generation of animal material	designed the experiment	Conceived and designed the experiments	Methodology	YES
5813380	29444639	RQ	PLoS52	designed the experiment|was responsible for the experimental protocols and generation of animal material	was responsible for the experimental protocols and generation of animal material	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5813380	29444639	TFC	PLoS52	performed rna extractions|analysed the rna sequencing data|carried out the rt-qpcr validation experiments|analysed the rt-qpcr data|wrote the paper	performed rna extractions	Performed the experiments	Investigation	YES
5813380	29444639	TFC	PLoS52	performed rna extractions|analysed the rna sequencing data|carried out the rt-qpcr validation experiments|analysed the rt-qpcr data|wrote the paper	analysed the rna sequencing data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5813380	29444639	TFC	PLoS52	performed rna extractions|analysed the rna sequencing data|carried out the rt-qpcr validation experiments|analysed the rt-qpcr data|wrote the paper	carried out the rt-qpcr validation experiments	Performed the experiments	Investigation|Validation	YES
5813380	29444639	TFC	PLoS52	performed rna extractions|analysed the rna sequencing data|carried out the rt-qpcr validation experiments|analysed the rt-qpcr data|wrote the paper	analysed the rt-qpcr data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5813380	29444639	TFC	PLoS52	performed rna extractions|analysed the rna sequencing data|carried out the rt-qpcr validation experiments|analysed the rt-qpcr data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5813380	29444639	all authors	PLoS52	contributed to the obtaining of biological samples	contributed to the obtaining of biological samples	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
2013938	17940617	BD	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2013938	17940617	BD	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2013938	17940617	DP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2013938	17940617	DP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2013938	17940617	DP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2013938	17940617	DP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2013938	17940617	DP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2013938	17940617	TO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2013938	17940617	TO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2013938	17940617	TO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2013938	17940617	TO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2013938	17940617	TO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418725	25938483	AEA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418725	25938483	AEA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418725	25938483	AEA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418725	25938483	AEA	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418725	25938483	AEFO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418725	25938483	AEFO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418725	25938483	AEFO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418725	25938483	AEFO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418725	25938483	AEFO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418725	25938483	ANH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418725	25938483	ANH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418725	25938483	ANH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418725	25938483	ANH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418725	25938483	HLS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418725	25938483	HLS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418725	25938483	HLS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418725	25938483	THA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418725	25938483	THA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418725	25938483	THA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418725	25938483	THA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418725	25938483	THA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5335779	28270914	HM	2	participated in drafting and revising the manuscript	participated in drafting and revising the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5335779	28270914	HN	2	participated in drafting and revising the manuscript	participated in drafting and revising the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5335779	28270914	JO	2	participated in drafting and revising the manuscript	participated in drafting and revising the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5335779	28270914	TK	2	participated in drafting and revising the manuscript	participated in drafting and revising the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5335779	28270914	TS	2	participated in drafting and revising the manuscript|participated in drafting and revising the manuscript	participated in drafting and revising the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5335779	28270914	TS	2	participated in drafting and revising the manuscript|participated in drafting and revising the manuscript	participated in drafting and revising the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5335779	28270914	TU	2	participated in drafting and revising the manuscript	participated in drafting and revising the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5335779	28270914	YS	2	participated in drafting and revising the manuscript	participated in drafting and revising the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3662316	23592547	WW	2	designed and supervised the study	designed and supervised the study	Conceived and designed the experiments	Methodology|Supervision	YES
3662316	23592547	YF	2	designed and supervised the study	designed and supervised the study	Conceived and designed the experiments	Methodology|Supervision	YES
6004267	29909506	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6004267	29909506	C-SP	2	designed and coordinated all the experiments|prepared the manuscript, evaluated the results and revised the manuscript	designed and coordinated all the experiments	Conceived and designed the experiments	Methodology|Project administration	YES
6004267	29909506	C-SP	2	designed and coordinated all the experiments|prepared the manuscript, evaluated the results and revised the manuscript	prepared the manuscript, evaluated the results and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6004267	29909506	D-HJ	2	performed anaerobic cultivation of the human fecal microbiome	performed anaerobic cultivation of the human fecal microbiome	Performed the experiments	Investigation	YES
6004267	29909506	D-HS	2	designed and coordinated all the experiments|prepared the manuscript, evaluated the results and revised the manuscript	designed and coordinated all the experiments	Conceived and designed the experiments	Methodology|Project administration	YES
6004267	29909506	D-HS	2	designed and coordinated all the experiments|prepared the manuscript, evaluated the results and revised the manuscript	prepared the manuscript, evaluated the results and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6004267	29909506	E-JS	2	performed statistical analysis and metagenome analysis of human fecal microbial change	performed statistical analysis and metagenome analysis of human fecal microbial change	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6004267	29909506	GK	2	conducted experiments on pectin degradation of human fecal microbiome|prepared the manuscript, evaluated the results and revised the manuscript	conducted experiments on pectin degradation of human fecal microbiome	Performed the experiments	Investigation	YES
6004267	29909506	GK	2	conducted experiments on pectin degradation of human fecal microbiome|prepared the manuscript, evaluated the results and revised the manuscript	prepared the manuscript, evaluated the results and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6004267	29909506	J-SK	2	confirmed the scfa production by ion chromatography analysis	confirmed the scfa production by ion chromatography analysis	Performed the experiments	Investigation	YES
6004267	29909506	MYL	2	performed statistical analysis and metagenome analysis of human fecal microbial change	performed statistical analysis and metagenome analysis of human fecal microbial change	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6004267	29909506	S-JB	2	performed the experiments and analyzed the gut microbiota data|prepared the manuscript, evaluated the results and revised the manuscript	performed the experiments and analyzed the gut microbiota data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6004267	29909506	S-JB	2	performed the experiments and analyzed the gut microbiota data|prepared the manuscript, evaluated the results and revised the manuscript	prepared the manuscript, evaluated the results and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6004267	29909506	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
6004267	29909506	Y-DN	2	performed statistical analysis and metagenome analysis of human fecal microbial change	performed statistical analysis and metagenome analysis of human fecal microbial change	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270861	25068782	Bunjerd Jongsomjit	1	Thai students	Thai students	-	-	NO
6270861	25068782	Piyasan Praserthdam	1	Thai students	Thai students	-	-	NO
5566890	28808109	S.H.T.	2	designed experiments and statistical analyses, and co-wrote the article|carried out measurements	designed experiments and statistical analyses, and co-wrote the article	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5566890	28808109	S.H.T.	2	designed experiments and statistical analyses, and co-wrote the article|carried out measurements	carried out measurements	Performed the experiments	Investigation	YES
5566890	28808109	S.L.	2	designed experiments and statistical analyses, and co-wrote the article	designed experiments and statistical analyses, and co-wrote the article	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4289843	25578971	All authors	2	have reviewed and contributed to the different draft versions of the manuscript and have read and approved the final manuscript	have reviewed and contributed to the different draft versions of the manuscript and have read and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4289843	25578971	IT	2	experimental procedures, immunohistochemical processing, microscopic analysis, data collection and/or preparation of figures	experimental procedures, immunohistochemical processing, microscopic analysis, data collection and/or preparation of figures	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation|Visualization	YES
4289843	25578971	KO	2	experimental procedures, immunohistochemical processing, microscopic analysis, data collection and/or preparation of figures	experimental procedures, immunohistochemical processing, microscopic analysis, data collection and/or preparation of figures	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation|Visualization	YES
4289843	25578971	NK	2	experimental procedures, immunohistochemical processing, microscopic analysis, data collection and/or preparation of figures	experimental procedures, immunohistochemical processing, microscopic analysis, data collection and/or preparation of figures	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation|Visualization	YES
4289843	25578971	SF	2	study design	study design	Conceived and designed the experiments	Methodology	YES
4289843	25578971	YG	2	experimental procedures, immunohistochemical processing, microscopic analysis, data collection and/or preparation of figures	experimental procedures, immunohistochemical processing, microscopic analysis, data collection and/or preparation of figures	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation|Visualization	YES
4289843	25578971	YS	2	study design|experimental procedures, immunohistochemical processing, microscopic analysis, data collection and/or preparation of figures|contributed especially to western blot analysis	study design	Conceived and designed the experiments	Methodology	YES
4289843	25578971	YS	2	study design|experimental procedures, immunohistochemical processing, microscopic analysis, data collection and/or preparation of figures|contributed especially to western blot analysis	experimental procedures, immunohistochemical processing, microscopic analysis, data collection and/or preparation of figures	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation|Visualization	YES
4289843	25578971	YS	2	study design|experimental procedures, immunohistochemical processing, microscopic analysis, data collection and/or preparation of figures|contributed especially to western blot analysis	contributed especially to western blot analysis	Performed the experiments	Investigation	YES
5341444	28286656	AM	2	reviewed and were involved in discussing and editing the manuscript	reviewed and were involved in discussing and editing the manuscript	Wrote the paper	Writing - Review & Editing	YES
5341444	28286656	FAR	2	conceptualized and drafted the manuscript	conceptualized and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5341444	28286656	GB	2	reviewed and were involved in discussing and editing the manuscript	reviewed and were involved in discussing and editing the manuscript	Wrote the paper	Writing - Review & Editing	YES
5341444	28286656	NL	2	conceptualized and drafted the manuscript	conceptualized and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5341444	28286656	PP	2	reviewed and were involved in discussing and editing the manuscript	reviewed and were involved in discussing and editing the manuscript	Wrote the paper	Writing - Review & Editing	YES
5341444	28286656	WEE	2	reviewed and were involved in discussing and editing the manuscript	reviewed and were involved in discussing and editing the manuscript	Wrote the paper	Writing - Review & Editing	YES
5813387	29444662	JC	2	conceived the study|interpreted the data|wrote the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5813387	29444662	JC	2	conceived the study|interpreted the data|wrote the manuscript	interpreted the data	Analyzed the data	Formal analysis	YES
5813387	29444662	JC	2	conceived the study|interpreted the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5813387	29444662	JS	2	conceived the study|performed data analysis|interpreted the data|wrote the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5813387	29444662	JS	2	conceived the study|performed data analysis|interpreted the data|wrote the manuscript	performed data analysis	Analyzed the data	Formal analysis	YES
5813387	29444662	JS	2	conceived the study|performed data analysis|interpreted the data|wrote the manuscript	interpreted the data	Analyzed the data	Formal analysis	YES
5813387	29444662	JS	2	conceived the study|performed data analysis|interpreted the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5813387	29444662	TG	2	conceived the study|performed data analysis|interpreted the data	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5813387	29444662	TG	2	conceived the study|performed data analysis|interpreted the data	performed data analysis	Analyzed the data	Formal analysis	YES
5813387	29444662	TG	2	conceived the study|performed data analysis|interpreted the data	interpreted the data	Analyzed the data	Formal analysis	YES
5835131	29535747	All authors	2	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
2013939	17940609	AD	PLoS5	Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2013939	17940609	AD	PLoS5	Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2013939	17940609	AD	PLoS5	Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2013939	17940609	AD	PLoS5	Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2013939	17940609	AD	PLoS5	Conceived and designed the experiments|Performed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2013939	17940609	AS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed to the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2013939	17940609	AS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed to the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2013939	17940609	AS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed to the paper	Contributed to the paper	-	-	NO
2013939	17940609	BK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
2013939	17940609	CL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed to the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2013939	17940609	CL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed to the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2013939	17940609	CL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed to the paper	Contributed to the paper	-	-	NO
2013939	17940609	DAD	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2013939	17940609	DAD	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
2013939	17940609	DJD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2013939	17940609	DJD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2013939	17940609	DJD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2013939	17940609	DJD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2013939	17940609	EM	PLoS5	Conceived and designed the experiments|Contributed to the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2013939	17940609	EM	PLoS5	Conceived and designed the experiments|Contributed to the paper	Contributed to the paper	-	-	NO
2013939	17940609	GM	PLoS5	Conceived and designed the experiments|Contributed to the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2013939	17940609	GM	PLoS5	Conceived and designed the experiments|Contributed to the paper	Contributed to the paper	-	-	NO
2013939	17940609	IS	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2013939	17940609	KM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed to the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2013939	17940609	KM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed to the paper	Performed the experiments	Performed the experiments	Investigation	YES
2013939	17940609	KM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed to the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2013939	17940609	KM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed to the paper	Contributed to the paper	-	-	NO
2013939	17940609	LM	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2013939	17940609	LM	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2013939	17940609	MA	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
2013939	17940609	MB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
2013939	17940609	MF	PLoS5	Analyzed the data|Contributed to the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2013939	17940609	MF	PLoS5	Analyzed the data|Contributed to the paper	Contributed to the paper	-	-	NO
2013939	17940609	MN	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
2013939	17940609	MS	PLoS5	Performed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
2013939	17940609	MS	PLoS5	Performed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
2013939	17940609	MT	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2013939	17940609	MT	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
2013939	17940609	OD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed to the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2013939	17940609	OD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed to the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2013939	17940609	OD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed to the paper	Contributed to the paper	-	-	NO
2013939	17940609	OG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
3662317	23505126	BAB	2	solved the identity of the vel carrier protein by mass-spectrometry analysis and wrote the manuscript	solved the identity of the vel carrier protein by mass-spectrometry analysis and wrote the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3662317	23505126	CS	2	prepared rbc membrane extracts and performed silver staining analysis	prepared rbc membrane extracts and performed silver staining analysis	Performed the experiments	Investigation	YES
3662317	23505126	JPC	2	continuously supported the project|was approved by all authors before submission	continuously supported the project	-	-	NO
3662317	23505126	JPC	2	continuously supported the project|was approved by all authors before submission	was approved by all authors before submission	-	-	NO
3662317	23505126	LA	2	conceived and supervised the study, set up the purification of the vel carrier protein, designed and performed the rflp analysis, made the dna constructs, made the figures and wrote the manuscript	conceived and supervised the study, set up the purification of the vel carrier protein, designed and performed the rflp analysis, made the dna constructs, made the figures and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Supervision|Visualization|Writing - Original Draft	YES
3662317	23505126	MLG	2	designed and performed the hrm analysis|was approved by all authors before submission	designed and performed the hrm analysis	Conceived and designed the experiments|Performed the experiments	Investigation	YES
3662317	23505126	MLG	2	designed and performed the hrm analysis|was approved by all authors before submission	was approved by all authors before submission	-	-	NO
3662317	23505126	TP	2	was approved by all authors before submission	was approved by all authors before submission	-	-	NO
3662317	23505126	VH	2	performed the large-scale purification of the vel carrier protein, genomic dna sequencing and flow cytometry analysis	performed the large-scale purification of the vel carrier protein, genomic dna sequencing and flow cytometry analysis	Performed the experiments	Investigation	YES
4418726	25938435	CL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418726	25938435	FY	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418726	25938435	GS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418726	25938435	JY	PLoS5	Revised the manuscript	Revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4418726	25938435	MS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418726	25938435	QT	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418726	25938435	SH	PLoS5	Revised the manuscript	Revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4418726	25938435	SS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418726	25938435	SS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418726	25938435	TC	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4418726	25938435	TC	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418726	25938435	XW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418726	25938435	XW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418726	25938435	XW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418726	25938435	XW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418726	25938435	YL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418726	25938435	YL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418726	25938435	YL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418726	25938435	YL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6004268	29909539	All authors	2	have contributed to this research work|read and approved the final manuscript	have contributed to this research work	Performed the experiments	Investigation	YES
6004268	29909539	All authors	2	have contributed to this research work|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5577459	28847818	A.J.G.	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5577459	28847818	J.R.M.	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
2013940	17940598	EC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2013940	17940598	EC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2013940	17940598	EC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2013940	17940598	EC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2013940	17940598	TK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2013940	17940598	TK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2013940	17940598	TK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5351209	28331621	AH	2	was responsible for writing the manuscript and collection of the data	was responsible for writing the manuscript and collection of the data	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5351209	28331621	AM	2	was responsible for conception of the topic and revision of the manuscript	was responsible for conception of the topic and revision of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5351209	28331621	HN	2	helped in writing and revising the manuscript	helped in writing and revising the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6270862	25347454	Allan Lancon	2	performed experiments on resveratrol-bovine serum albumin binding sites	performed experiments on resveratrol-bovine serum albumin binding sites	Performed the experiments	Investigation	YES
6270862	25347454	Dominique Delmas	2	brought his experience on resveratrol and prepared protocols	brought his experience on resveratrol and prepared protocols	Conceived and designed the experiments	Methodology	YES
6270862	25347454	Matthias Menzel	2	performed experiments on resveratrol-bovine serum albumin fluorescence and on infrared spectra	performed experiments on resveratrol-bovine serum albumin fluorescence and on infrared spectra	Performed the experiments	Investigation	YES
6270862	25347454	Norbert Latruffe	2	as principal investigator initiated the project, managed it and wrote the paper	as principal investigator initiated the project, managed it and wrote the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Funding acquisition|Project administration|Writing - Original Draft	YES
6270862	25347454	Rene Buchet	2	brought his experience, training and interpretation on infrared spectra	brought his experience, training and interpretation on infrared spectra	Analyzed the data	Formal analysis	YES
5815192	29448945	AS	2	performed the entire bioinformatics and statistical analysis for the study	performed the entire bioinformatics and statistical analysis for the study	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5815192	29448945	AV	2	conducted the rna sequencing and performed the quality control experiments	conducted the rna sequencing and performed the quality control experiments	Performed the experiments	Investigation|Validation	YES
5815192	29448945	All authors	2	were involved in drafting of the manuscript	were involved in drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
5815192	29448945	KK	2	conceived and supervised the entire study|standardized the assays and performed molecular biology experiments for the study|performed the entire bioinformatics and statistical analysis for the study	conceived and supervised the entire study	Conceived and designed the experiments	Conceptualization|Supervision	YES
5815192	29448945	KK	2	conceived and supervised the entire study|standardized the assays and performed molecular biology experiments for the study|performed the entire bioinformatics and statistical analysis for the study	standardized the assays and performed molecular biology experiments for the study	Performed the experiments	Investigation	YES
5815192	29448945	KK	2	conceived and supervised the entire study|standardized the assays and performed molecular biology experiments for the study|performed the entire bioinformatics and statistical analysis for the study	performed the entire bioinformatics and statistical analysis for the study	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5815192	29448945	RJ	2	conducted the rna sequencing and performed the quality control experiments	conducted the rna sequencing and performed the quality control experiments	Performed the experiments	Investigation|Validation	YES
5815192	29448945	SKV	2	conducted the rna sequencing and performed the quality control experiments	conducted the rna sequencing and performed the quality control experiments	Performed the experiments	Investigation|Validation	YES
5815192	29448945	SM	2	conceived and supervised the entire study|interpreted the findings	conceived and supervised the entire study	Conceived and designed the experiments	Conceptualization|Supervision	YES
5815192	29448945	SM	2	conceived and supervised the entire study|interpreted the findings	interpreted the findings	Analyzed the data	Formal analysis	YES
5815192	29448945	SSB	2	conceived and supervised the entire study	conceived and supervised the entire study	Conceived and designed the experiments	Conceptualization|Supervision	YES
5815192	29448945	TS	2	performed the entire bioinformatics and statistical analysis for the study	performed the entire bioinformatics and statistical analysis for the study	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5815192	29448945	VS	2	conceived and supervised the entire study	conceived and supervised the entire study	Conceived and designed the experiments	Conceptualization|Supervision	YES
4418727	25938516	ARS	PLoS5	Performed the experiments|Analyzed the data|Critical review and approval of the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4418727	25938516	ARS	PLoS5	Performed the experiments|Analyzed the data|Critical review and approval of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4418727	25938516	ARS	PLoS5	Performed the experiments|Analyzed the data|Critical review and approval of the manuscript	Critical review and approval of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4418727	25938516	DGD	PLoS5	Conceived and designed the experiments|Critical review and approval of the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418727	25938516	DGD	PLoS5	Conceived and designed the experiments|Critical review and approval of the manuscript	Critical review and approval of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4418727	25938516	JAB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418727	25938516	JAB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418727	25938516	JAB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418727	25938516	JAB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418727	25938516	JI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Critical review and approval of the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418727	25938516	JI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Critical review and approval of the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4418727	25938516	JI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Critical review and approval of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4418727	25938516	JI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Critical review and approval of the manuscript	Critical review and approval of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4418727	25938516	JJAB	PLoS5	Performed the experiments|Analyzed the data|Critical review and approval of the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4418727	25938516	JJAB	PLoS5	Performed the experiments|Analyzed the data|Critical review and approval of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4418727	25938516	JJAB	PLoS5	Performed the experiments|Analyzed the data|Critical review and approval of the manuscript	Critical review and approval of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4418727	25938516	LA	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Critical review and approval of the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418727	25938516	LA	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Critical review and approval of the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4418727	25938516	LA	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Critical review and approval of the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418727	25938516	LA	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Critical review and approval of the manuscript	Critical review and approval of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5835234	29535752	All authors	2	discussed and commented the manuscript	discussed and commented the manuscript	-	-	NO
3662318	23584892	ADC	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
3662318	23584892	CNS	2	designed the experiments, analyzed data and wrote the paper	designed the experiments, analyzed data and wrote the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3662318	23584892	CT	2	designed experiments and advised on the analysis of data	designed experiments and advised on the analysis of data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
3662318	23584892	EA	2	designed the experiments, analyzed data and wrote the paper	designed the experiments, analyzed data and wrote the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3662318	23584892	KP	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
3662318	23584892	OK	2	performed experiments and wrote the paper	performed experiments and wrote the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3662318	23584892	PS	2	designed experiments and advised on the analysis of data	designed experiments and advised on the analysis of data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
3662318	23584892	SK	2	performed experiments and wrote the paper	performed experiments and wrote the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3662318	23584892	TV	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
4289845	25578973	EG	2	contributed equally to this work	contributed equally to this work	-	-	NO
4289845	25578973	MA	2	contributed equally to this work	contributed equally to this work	-	-	NO
6008271	29922919	CL	1	Experimentation	Experimentation	Performed the experiments	Investigation	YES
6008271	29922919	XHG	1	Planning and designing of the study|Manuscript drafting	Planning and designing of the study	Conceived and designed the experiments	Methodology	YES
6008271	29922919	XHG	1	Planning and designing of the study|Manuscript drafting	Manuscript drafting	Wrote the paper	Writing - Original Draft	YES
6008271	29922919	XSL	1	Experimentation	Experimentation	Performed the experiments	Investigation	YES
6008271	29922919	ZL	1	Data analysis	Data analysis	Analyzed the data	Formal analysis	YES
5359904	28331622	AK	2	designed the study, analyzed data, and wrote the manuscript	designed the study, analyzed data, and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5359904	28331622	All authors	2	took part in the manuscript writing and approved the final manuscript	took part in the manuscript writing and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5359904	28331622	CB	2	collected the data and assisted in patient recruitment	collected the data and assisted in patient recruitment	Performed the experiments	Investigation	YES
5359904	28331622	CT	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5359904	28331622	EY	2	performed the laboratory measurements	performed the laboratory measurements	Performed the experiments	Investigation	YES
5359904	28331622	FT	2	designed the study, analyzed data, and wrote the manuscript	designed the study, analyzed data, and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5359904	28331622	JB	2	collected the data and assisted in patient recruitment	collected the data and assisted in patient recruitment	Performed the experiments	Investigation	YES
5359904	28331622	LB	2	designed the study, analyzed data, and wrote the manuscript	designed the study, analyzed data, and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5359904	28331622	UH	2	collected the data and assisted in patient recruitment	collected the data and assisted in patient recruitment	Performed the experiments	Investigation	YES
2013941	17940613	CH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2013941	17940613	CH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2013941	17940613	CH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2013941	17940613	CH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2013941	17940613	OS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2013941	17940613	OS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2013941	17940613	OS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2013941	17940613	OS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2013941	17940613	RK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2013941	17940613	RK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2013941	17940613	RK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2013941	17940613	RK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418728	25938510	AG	PLoS5	Performed the experiments|Analyzed the data|Critically reviewed and edited the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418728	25938510	AG	PLoS5	Performed the experiments|Analyzed the data|Critically reviewed and edited the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418728	25938510	AG	PLoS5	Performed the experiments|Analyzed the data|Critically reviewed and edited the paper	Critically reviewed and edited the paper	Wrote the paper	Writing - Review & Editing	YES
4418728	25938510	CJA	PLoS5	Contributed reagents/materials/analysis tools|Critically reviewed and edited the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418728	25938510	CJA	PLoS5	Contributed reagents/materials/analysis tools|Critically reviewed and edited the paper	Critically reviewed and edited the paper	Wrote the paper	Writing - Review & Editing	YES
4418728	25938510	DNF	PLoS5	Contributed reagents/materials/analysis tools|Critically reviewed and edited the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418728	25938510	DNF	PLoS5	Contributed reagents/materials/analysis tools|Critically reviewed and edited the paper	Critically reviewed and edited the paper	Wrote the paper	Writing - Review & Editing	YES
4418728	25938510	EYD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Critically reviewed and edited the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418728	25938510	EYD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Critically reviewed and edited the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418728	25938510	EYD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Critically reviewed and edited the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418728	25938510	EYD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Critically reviewed and edited the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418728	25938510	EYD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Critically reviewed and edited the paper	Critically reviewed and edited the paper	Wrote the paper	Writing - Review & Editing	YES
4418728	25938510	JSG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Critically reviewed and edited the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418728	25938510	JSG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Critically reviewed and edited the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418728	25938510	JSG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Critically reviewed and edited the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418728	25938510	JSG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Critically reviewed and edited the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418728	25938510	JSG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Critically reviewed and edited the paper	Critically reviewed and edited the paper	Wrote the paper	Writing - Review & Editing	YES
4418728	25938510	PLF	PLoS5	Conceived and designed the experiments|Analyzed the data|Critically reviewed and edited the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418728	25938510	PLF	PLoS5	Conceived and designed the experiments|Analyzed the data|Critically reviewed and edited the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418728	25938510	PLF	PLoS5	Conceived and designed the experiments|Analyzed the data|Critically reviewed and edited the paper	Critically reviewed and edited the paper	Wrote the paper	Writing - Review & Editing	YES
4418728	25938510	SI	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Critically reviewed and edited the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418728	25938510	SI	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Critically reviewed and edited the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418728	25938510	SI	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Critically reviewed and edited the paper	Critically reviewed and edited the paper	Wrote the paper	Writing - Review & Editing	YES
5577460	28847819	I.T.	2	jointly visualized this topic, researched the literature and wrote the manuscript	jointly visualized this topic, researched the literature and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Visualization|Writing - Original Draft	YES
5577460	28847819	J.O.	2	jointly visualized this topic, researched the literature and wrote the manuscript|prepared the figures	jointly visualized this topic, researched the literature and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Visualization|Writing - Original Draft	YES
5577460	28847819	J.O.	2	jointly visualized this topic, researched the literature and wrote the manuscript|prepared the figures	prepared the figures	-	Visualization	YES
5577460	28847819	K.R.	2	jointly visualized this topic, researched the literature and wrote the manuscript	jointly visualized this topic, researched the literature and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Visualization|Writing - Original Draft	YES
4289846	25578974	AB	2	genetic analysis	genetic analysis	Performed the experiments	Investigation	YES
4289846	25578974	BF	2	data analysis, clinical evaluation, manuscript revision	data analysis, clinical evaluation, manuscript revision	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4289846	25578974	EC	2	data analysis, manuscript revision	data analysis, manuscript revision	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4289846	25578974	GM	2	study conceptualization, muscle histopathological and clinical evaluation, manuscript revision, final approval of the version to be published	study conceptualization, muscle histopathological and clinical evaluation, manuscript revision, final approval of the version to be published	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Review & Editing	YES
4289846	25578974	GR	2	telomere lenght analysis and interpretation of the data	telomere lenght analysis and interpretation of the data	Analyzed the data	Formal analysis	YES
4289846	25578974	LVR	2	myoblast cultures, western blotting analysis, data analysis and interpretation, participation in manuscript drafting	myoblast cultures, western blotting analysis, data analysis and interpretation, participation in manuscript drafting	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4289846	25578974	RC	2	study design, muscle histopathological evaluation, myoblast cultures, data analysis and interpretation, manuscript drafting	study design, muscle histopathological evaluation, myoblast cultures, data analysis and interpretation, manuscript drafting	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
3662319	23606583	All	2	contributed to the writing and correction of the manuscript	contributed to the writing and correction of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3662319	23606583	GS	2	initiated the project and supervised the work	initiated the project and supervised the work	Conceived and designed the experiments	Conceptualization|Supervision	YES
3662319	23606583	MC	2	has performed most of the experiments	has performed most of the experiments	Performed the experiments	Investigation	YES
3662319	23606583	MR	2	provided the expertise for the caco-2/dcs co-culture system	provided the expertise for the caco-2/dcs co-culture system	Performed the experiments	Investigation	YES
4156244	25119431	J.G.D.	2	equally contributed	equally contributed	-	-	NO
4156244	25119431	W.-J.B.	2	equally contributed	equally contributed	-	-	NO
6270864	25140448	Fang Xu	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6270864	25140448	Hong Chen	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6270864	25140448	Mu Yuan	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5835310	29535746	AB	2	was in charge of plant materials selection and samples collection	was in charge of plant materials selection and samples collection	Performed the experiments	Investigation	YES
5835310	29535746	All authors	2	conceived and designed the experiment	conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
5835310	29535746	LL	2	performed fruit traits and oil quality analysis|prepared the first draft of the manuscript	performed fruit traits and oil quality analysis	Performed the experiments	Investigation	YES
5835310	29535746	LL	2	performed fruit traits and oil quality analysis|prepared the first draft of the manuscript	prepared the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
5835310	29535746	LV	2	performed fruit traits and oil quality analysis	performed fruit traits and oil quality analysis	Performed the experiments	Investigation	YES
5835310	29535746	RdlR	2	performed fruit traits and oil quality analysis	performed fruit traits and oil quality analysis	Performed the experiments	Investigation	YES
5835310	29535746	all authors	2	critically reviewed the manuscript prior to submission, read and approved the final version of the manuscript and agreed to be accountable for accuracy, integrity, and appropriateness of the manuscript	critically reviewed the manuscript prior to submission, read and approved the final version of the manuscript and agreed to be accountable for accuracy, integrity, and appropriateness of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5816523	29454312	HS	2	conducted the animal trial and collected samples|prepared libraries, analyzed data, and wrote the manuscript|contributed equally to this study	conducted the animal trial and collected samples	Performed the experiments	Investigation	YES
5816523	29454312	HS	2	conducted the animal trial and collected samples|prepared libraries, analyzed data, and wrote the manuscript|contributed equally to this study	prepared libraries, analyzed data, and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5816523	29454312	HS	2	conducted the animal trial and collected samples|prepared libraries, analyzed data, and wrote the manuscript|contributed equally to this study	contributed equally to this study	-	-	NO
5816523	29454312	HZ	2	conducted the animal trial and collected samples	conducted the animal trial and collected samples	Performed the experiments	Investigation	YES
5816523	29454312	JZ	2	conducted the animal trial and collected samples|prepared libraries, analyzed data, and wrote the manuscript|contributed equally to this study	conducted the animal trial and collected samples	Performed the experiments	Investigation	YES
5816523	29454312	JZ	2	conducted the animal trial and collected samples|prepared libraries, analyzed data, and wrote the manuscript|contributed equally to this study	prepared libraries, analyzed data, and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5816523	29454312	JZ	2	conducted the animal trial and collected samples|prepared libraries, analyzed data, and wrote the manuscript|contributed equally to this study	contributed equally to this study	-	-	NO
5816523	29454312	SJ	2	conducted the animal trial and collected samples	conducted the animal trial and collected samples	Performed the experiments	Investigation	YES
5816523	29454312	SL	2	designed the study|revised the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5816523	29454312	SL	2	designed the study|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5816523	29454312	YW	2	designed the study|revised the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5816523	29454312	YW	2	designed the study|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5816523	29454312	ZC	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
4289847	25578975	AG	2	study design, data analysis, writing and revision of the manuscript	study design, data analysis, writing and revision of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
4289847	25578975	AH	2	study design, data analysis, writing and revision of the manuscript	study design, data analysis, writing and revision of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
4289847	25578975	BE	2	histological preparations and staining|study design, data analysis, writing and revision of the manuscript	histological preparations and staining	Performed the experiments	Investigation	YES
4289847	25578975	BE	2	histological preparations and staining|study design, data analysis, writing and revision of the manuscript	study design, data analysis, writing and revision of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
4289847	25578975	KB	2	histological preparations and staining|study design, data analysis, writing and revision of the manuscript	histological preparations and staining	Performed the experiments	Investigation	YES
4289847	25578975	KB	2	histological preparations and staining|study design, data analysis, writing and revision of the manuscript	study design, data analysis, writing and revision of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
6008273	29923151	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5577463	28847822	H.v.A.	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5577463	28847822	M.B.R.	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6270865	25264831	Mohamed Sakran	2	have supervised the study|performed the biological assays and analyzed the results of hepatotoxicity and revised the paper	have supervised the study	-	Supervision	YES
6270865	25264831	Mohamed Sakran	2	have supervised the study|performed the biological assays and analyzed the results of hepatotoxicity and revised the paper	performed the biological assays and analyzed the results of hepatotoxicity and revised the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
6270865	25264831	Nahla Zidan	2	prepare the plant and performed in the biological assays	prepare the plant and performed in the biological assays	Performed the experiments	Investigation	YES
6270865	25264831	Yasser Selim	2	have supervised the study|have written and revised the paper|performed the isolation of new compounds and has analyzed the data	have supervised the study	-	Supervision	YES
6270865	25264831	Yasser Selim	2	have supervised the study|have written and revised the paper|performed the isolation of new compounds and has analyzed the data	have written and revised the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6270865	25264831	Yasser Selim	2	have supervised the study|have written and revised the paper|performed the isolation of new compounds and has analyzed the data	performed the isolation of new compounds and has analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5835311	29535743	BM	2	planned and supervised the study	planned and supervised the study	Conceived and designed the experiments	Conceptualization|Supervision	YES
5835311	29535743	CH	2	made the economical evaluation of the data	made the economical evaluation of the data	-	-	NO
5835311	29535743	CK	2	planned and supervised the study|analyzed the field data	planned and supervised the study	Conceived and designed the experiments	Conceptualization|Supervision	YES
5835311	29535743	CK	2	planned and supervised the study|analyzed the field data	analyzed the field data	Analyzed the data	Formal analysis	YES
5835311	29535743	JV	2	analyzed the field data|made the economical evaluation of the data	analyzed the field data	Analyzed the data	Formal analysis	YES
5835311	29535743	JV	2	analyzed the field data|made the economical evaluation of the data	made the economical evaluation of the data	-	-	NO
4658402	26640799	Aijun Liu	2	are equal contributors and are co-first authors	are equal contributors and are co-first authors	-	-	NO
4658402	26640799	Jin Lu	2	are equal contributors and are co-first authors	are equal contributors and are co-first authors	-	-	NO
4658402	26640799	Jing Lu	2	are equal contributors and are co-first authors	are equal contributors and are co-first authors	-	-	NO
2013942	17940603	AS	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2013942	17940603	AS	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2013942	17940603	AW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2013942	17940603	AW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2013942	17940603	AW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2013942	17940603	AW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2013942	17940603	CJ	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
2013942	17940603	CJ	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2013942	17940603	FW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2013942	17940603	FW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2013942	17940603	FW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2013942	17940603	FW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2013942	17940603	JH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2013942	17940603	JH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2013942	17940603	JH	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2013942	17940603	LG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2013942	17940603	LG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2013942	17940603	LG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2013942	17940603	RN	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2013942	17940603	RN	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2013942	17940603	RN	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2013942	17940603	YC	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2013942	17940603	YC	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2013942	17940603	ZW	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2013942	17940603	ZW	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5397695	28435684	All authors	2	critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5397695	28435684	FR	2	collected the data	collected the data	Performed the experiments	Investigation	YES
5397695	28435684	LH	2	conceived and designed the study|conducted the analysis and produced the first draft of the manuscript|collected the data	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5397695	28435684	LH	2	conceived and designed the study|conducted the analysis and produced the first draft of the manuscript|collected the data	conducted the analysis and produced the first draft of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5397695	28435684	LH	2	conceived and designed the study|conducted the analysis and produced the first draft of the manuscript|collected the data	collected the data	Performed the experiments	Investigation	YES
5397695	28435684	LYH	2	collected the data	collected the data	Performed the experiments	Investigation	YES
5397695	28435684	LYT	2	collected the data	collected the data	Performed the experiments	Investigation	YES
5397695	28435684	ZD	2	conducted the analysis and produced the first draft of the manuscript	conducted the analysis and produced the first draft of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4418729	25938808	CEC	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418729	25938808	CEC	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4418729	25938808	CEC	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418729	25938808	EF	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418729	25938808	EF	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4418729	25938808	EF	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418729	25938808	FD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418729	25938808	FD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418729	25938808	FD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418729	25938808	FD	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418729	25938808	LB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418729	25938808	LB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4418729	25938808	LB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418729	25938808	MM	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418729	25938808	MM	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418729	25938808	PR	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Review of the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418729	25938808	PR	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Review of the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4418729	25938808	PR	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Review of the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418729	25938808	PR	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Review of the manuscript	Review of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5819162	29458327	JS	2	all provided expert next generation sequencing	all provided expert next generation sequencing	Performed the experiments	Investigation	YES
5819162	29458327	LDC	2	all provided expert next generation sequencing	all provided expert next generation sequencing	Performed the experiments	Investigation	YES
5819162	29458327	MS	2	all provided expert next generation sequencing	all provided expert next generation sequencing	Performed the experiments	Investigation	YES
4418730	25938765	CP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418730	25938765	CP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418730	25938765	CP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418730	25938765	CP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418730	25938765	CP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418730	25938765	DI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418730	25938765	DI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418730	25938765	DI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418730	25938765	DI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418730	25938765	DI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418730	25938765	GDC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418730	25938765	GDC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418730	25938765	GDC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418730	25938765	GDC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418730	25938765	GDC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418730	25938765	VC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418730	25938765	VC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418730	25938765	VC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418730	25938765	VC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418730	25938765	VC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2013943	17940615	AP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2013943	17940615	AP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2013943	17940615	AP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2013943	17940615	AP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2013943	17940615	AP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2013943	17940615	CK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2013943	17940615	CK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2013943	17940615	CK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2013943	17940615	CK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2013943	17940615	CK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2013943	17940615	EK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2013943	17940615	EK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2013943	17940615	EK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2013943	17940615	HR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2013943	17940615	HR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
2013943	17940615	HR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
2013943	17940615	HR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2013943	17940615	HX	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
2013943	17940615	HX	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
2013943	17940615	HX	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2013943	17940615	JH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2013943	17940615	JH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2013943	17940615	JH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2013943	17940615	JH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2013943	17940615	JH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2013943	17940615	PM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the study|Wrote the first draft of the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2013943	17940615	PM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the study|Wrote the first draft of the paper	Performed the experiments	Performed the experiments	Investigation	YES
2013943	17940615	PM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the study|Wrote the first draft of the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2013943	17940615	PM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the study|Wrote the first draft of the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2013943	17940615	PM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the study|Wrote the first draft of the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2013943	17940615	PM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the study|Wrote the first draft of the paper	Designed the study	Conceived and designed the experiments	Methodology	YES
2013943	17940615	PM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the study|Wrote the first draft of the paper	Wrote the first draft of the paper	Wrote the paper	Writing - Original Draft	YES
2013943	17940615	RA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2013943	17940615	RA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2013943	17940615	RA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2013943	17940615	RA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2013943	17940615	RA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2013943	17940615	VB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2013943	17940615	VB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2013943	17940615	VB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2013943	17940615	VB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2013943	17940615	VB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270866	25006785	B.P.V.D.	2	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270866	25006785	C.A.C.	2	performed the isolation and purification of natural lapachol, synthesis of oxime and full characterization of the active molecule	performed the isolation and purification of natural lapachol, synthesis of oxime and full characterization of the active molecule	Performed the experiments	Investigation	YES
6270866	25006785	F.F.F.	2	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270866	25006785	I.A.M.	2	have draft the manuscript	have draft the manuscript	Wrote the paper	Writing - Original Draft	YES
6270866	25006785	J.L.A.	2	have draft the manuscript	have draft the manuscript	Wrote the paper	Writing - Original Draft	YES
6270866	25006785	J.S.A.	2	performed the isolation and purification of natural lapachol, synthesis of oxime and full characterization of the active molecule	performed the isolation and purification of natural lapachol, synthesis of oxime and full characterization of the active molecule	Performed the experiments	Investigation	YES
6270866	25006785	K.S.A.	2	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270866	25006785	MSF-S	2	have draft the manuscript	have draft the manuscript	Wrote the paper	Writing - Original Draft	YES
6270866	25006785	T.M.S.S.	2	performed the isolation and purification of natural lapachol, synthesis of oxime and full characterization of the active molecule	performed the isolation and purification of natural lapachol, synthesis of oxime and full characterization of the active molecule	Performed the experiments	Investigation	YES
6270866	25006785	T.P.R.	2	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270866	25006785	V.A.B.	2	has corrected the final version of the manuscript and coordinated the study	has corrected the final version of the manuscript and coordinated the study	Wrote the paper	Project administration|Writing - Review & Editing	YES
6270866	25006785	V.L.A.	2	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6008275	29923143	All	2	data supporting the results and discussion, and conclusions of this study are included in the manuscript	data supporting the results and discussion, and conclusions of this study are included in the manuscript	-	-	NO
6008275	29923143	All authors	2	provided comments before approving the manuscript|read and approved the final manuscript|gave their consent for publication	provided comments before approving the manuscript	-	-	NO
6008275	29923143	All authors	2	provided comments before approving the manuscript|read and approved the final manuscript|gave their consent for publication	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6008275	29923143	All authors	2	provided comments before approving the manuscript|read and approved the final manuscript|gave their consent for publication	gave their consent for publication	-	-	NO
6008275	29923143	GP	2	provided feedback during manuscript writing and helped edit the manuscript	provided feedback during manuscript writing and helped edit the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6008275	29923143	PP	2	conceived study, and designed experiment and wrote manuscript with	conceived study, and designed experiment and wrote manuscript with	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
6008275	29923143	RA	2	provided feedback during manuscript writing and helped edit the manuscript	provided feedback during manuscript writing and helped edit the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6008275	29923143	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
6008275	29923143	YW	2	carried out experiments and analyzed samples|helped with the and designed experiment and wrote manuscript with	carried out experiments and analyzed samples	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6008275	29923143	YW	2	carried out experiments and analyzed samples|helped with the and designed experiment and wrote manuscript with	helped with the and designed experiment and wrote manuscript with	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
6008275	29923143	YZ	2	carried out experiments and analyzed samples|helped with the and designed experiment and wrote manuscript with	carried out experiments and analyzed samples	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6008275	29923143	YZ	2	carried out experiments and analyzed samples|helped with the and designed experiment and wrote manuscript with	helped with the and designed experiment and wrote manuscript with	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
4156252	25153792	B.J.	2	contributed equally	contributed equally	-	-	NO
4156252	25153792	H.J.	2	contributed equally	contributed equally	-	-	NO
5440980	28546861	AC	2	contributed to the conception and design of the study, to acquire the data, and reviewed the manuscript	contributed to the conception and design of the study, to acquire the data, and reviewed the manuscript	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Investigation|Methodology|Resources|Writing - Review & Editing	YES
5440980	28546861	AM	2	contributed to the conception and design of the study and drafted and reviewed the manuscript critically for important intellectual content	contributed to the conception and design of the study and drafted and reviewed the manuscript critically for important intellectual content	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5440980	28546861	BS	2	contributed to the conception and design of the study, to acquire the data and to analyse and interpret the data, and drafted and reviewed the manuscript	contributed to the conception and design of the study, to acquire the data and to analyse and interpret the data, and drafted and reviewed the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5440980	28546861	CR	2	contributed to the conception and design of the study and drafted and reviewed the manuscript critically for important intellectual content	contributed to the conception and design of the study and drafted and reviewed the manuscript critically for important intellectual content	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5440980	28546861	ER	2	contributed to the conception and design of the study, to acquire the data and to analyse and interpret the data, and drafted and reviewed the manuscript	contributed to the conception and design of the study, to acquire the data and to analyse and interpret the data, and drafted and reviewed the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5440980	28546861	JR	2	contributed to acquire the data and reviewed the manuscript	contributed to acquire the data and reviewed the manuscript	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Resources|Writing - Review & Editing	YES
5440980	28546861	LB	2	contributed to acquire the data and reviewed the manuscript	contributed to acquire the data and reviewed the manuscript	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Resources|Writing - Review & Editing	YES
5440980	28546861	MH	2	contributed to acquire the data and reviewed the manuscript	contributed to acquire the data and reviewed the manuscript	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Resources|Writing - Review & Editing	YES
5440980	28546861	MS	2	analysed and interpreted the data and drafted and reviewed the manuscript	analysed and interpreted the data and drafted and reviewed the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
4418731	25938764	KH	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418731	25938764	P. Makela	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418731	25938764	P. Makela	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418731	25938764	P. Martikainen	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418731	25938764	P. Martikainen	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418731	25938764	T. Paljarvi	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418731	25938764	T. Paljarvi	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418731	25938764	T. Paljarvi	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418731	25938764	T. Pensola	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418731	25938764	TL	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418731	25938764	TL	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5819184	29458354	BV	2	analyzed and interpreted the data	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5819184	29458354	EK	2	designed the research|analyzed and interpreted the data	designed the research	Conceived and designed the experiments	Methodology	YES
5819184	29458354	EK	2	designed the research|analyzed and interpreted the data	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5819184	29458354	JC	2	performed genome size measurements	performed genome size measurements	Performed the experiments	Investigation	YES
5819184	29458354	JP	2	performed bioinformatics data analysis	performed bioinformatics data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5819184	29458354	RH	2	designed the research|analyzed and interpreted the data	designed the research	Conceived and designed the experiments	Methodology	YES
5819184	29458354	RH	2	designed the research|analyzed and interpreted the data	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5819184	29458354	ZK	2	designed the research|analyzed and interpreted the data	designed the research	Conceived and designed the experiments	Methodology	YES
5819184	29458354	ZK	2	designed the research|analyzed and interpreted the data	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5835324	29535753	AK	7	prepared the figures; AK, NL, MyC, and Fd	prepared the figures; AK, NL, MyC, and Fd	-	Visualization	YES
5835324	29535753	C-N	7	conceived the project; AK, NL, MyC, and Fd|designed the experiments|wrote the manuscript; MyC and Fd|are co-responsible for the work	conceived the project; AK, NL, MyC, and Fd	Conceived and designed the experiments	Conceptualization	YES
5835324	29535753	C-N	7	conceived the project; AK, NL, MyC, and Fd|designed the experiments|wrote the manuscript; MyC and Fd|are co-responsible for the work	designed the experiments	Conceived and designed the experiments	Methodology	YES
5835324	29535753	C-N	7	conceived the project; AK, NL, MyC, and Fd|designed the experiments|wrote the manuscript; MyC and Fd|are co-responsible for the work	wrote the manuscript; MyC and Fd	Wrote the paper	Writing - Original Draft	YES
5835324	29535753	C-N	7	conceived the project; AK, NL, MyC, and Fd|designed the experiments|wrote the manuscript; MyC and Fd|are co-responsible for the work	are co-responsible for the work	-	-	NO
5835324	29535753	FdAK	7	performed the m. truncatula and	performed the m. truncatula and	Performed the experiments	Investigation	YES
5835324	29535753	MiC	7	contributed to the nls-r-geco1 in rocs experiments	contributed to the nls-r-geco1 in rocs experiments	Performed the experiments	Investigation	YES
5835324	29535753	MyC	7	performed the m. truncatula and	performed the m. truncatula and	Performed the experiments	Investigation	YES
5835324	29535753	NL	7	the A. thaliana experiments|prepared the figures; AK, NL, MyC, and Fd	the A. thaliana experiments	-	-	NO
5835324	29535753	NL	7	the A. thaliana experiments|prepared the figures; AK, NL, MyC, and Fd	prepared the figures; AK, NL, MyC, and Fd	-	Visualization	YES
2013944	17940616	DS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2013944	17940616	DS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2013944	17940616	DS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2013944	17940616	SP	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2013944	17940616	SP	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418732	25938673	IK	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418732	25938673	MK	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418732	25938673	MK	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418732	25938673	SL	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418732	25938673	SL	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6015585	29936673	All	2	raw data are available at the corresponding author	raw data are available at the corresponding author	-	-	NO
6015585	29936673	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6015585	29936673	FN	2	helped to revise the manuscript	helped to revise the manuscript	Wrote the paper	Writing - Review & Editing	YES
6015585	29936673	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
6015585	29936673	XQZ	2	participated in designing the experimental program	participated in designing the experimental program	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6015585	29936673	XYL	2	performed the experiments and wrote the paper|equally contributed to this work	performed the experiments and wrote the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6015585	29936673	XYL	2	performed the experiments and wrote the paper|equally contributed to this work	equally contributed to this work	-	-	NO
6015585	29936673	YXG	2	designed the experiments and wrote the paper|equally contributed to this work	designed the experiments and wrote the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
6015585	29936673	YXG	2	designed the experiments and wrote the paper|equally contributed to this work	equally contributed to this work	-	-	NO
6015585	29936673	YY	2	participated in designing the experimental program	participated in designing the experimental program	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6015585	29936673	ZW	2	participated in designing the experimental program	participated in designing the experimental program	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5441045	28546860	AE	2	contributed to the study design	contributed to the study design	Conceived and designed the experiments	Methodology	YES
5441045	28546860	AET	2	contributed to the study design	contributed to the study design	Conceived and designed the experiments	Methodology	YES
5441045	28546860	AFS	2	contributed to the study design|contributed to the data collection|contributed to the data interpretation|contributed to the draft of the manuscript	contributed to the study design	Conceived and designed the experiments	Methodology	YES
5441045	28546860	AFS	2	contributed to the study design|contributed to the data collection|contributed to the data interpretation|contributed to the draft of the manuscript	contributed to the data collection	Performed the experiments	Investigation	YES
5441045	28546860	AFS	2	contributed to the study design|contributed to the data collection|contributed to the data interpretation|contributed to the draft of the manuscript	contributed to the data interpretation	Analyzed the data	Formal analysis	YES
5441045	28546860	AFS	2	contributed to the study design|contributed to the data collection|contributed to the data interpretation|contributed to the draft of the manuscript	contributed to the draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
5441045	28546860	All authors	2	contributed to the revision and approval of the manuscript	contributed to the revision and approval of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5441045	28546860	BB	2	contributed to the study design|contributed to the data interpretation|contributed to the study supervision	contributed to the study design	Conceived and designed the experiments	Methodology	YES
5441045	28546860	BB	2	contributed to the study design|contributed to the data interpretation|contributed to the study supervision	contributed to the data interpretation	Analyzed the data	Formal analysis	YES
5441045	28546860	BB	2	contributed to the study design|contributed to the data interpretation|contributed to the study supervision	contributed to the study supervision	-	Supervision	YES
5441045	28546860	ET	2	contributed to the study design|contributed to the statistical analysis|contributed to the data interpretation|contributed to the draft of the manuscript	contributed to the study design	Conceived and designed the experiments	Methodology	YES
5441045	28546860	ET	2	contributed to the study design|contributed to the statistical analysis|contributed to the data interpretation|contributed to the draft of the manuscript	contributed to the statistical analysis	Analyzed the data	Formal analysis	YES
5441045	28546860	ET	2	contributed to the study design|contributed to the statistical analysis|contributed to the data interpretation|contributed to the draft of the manuscript	contributed to the data interpretation	Analyzed the data	Formal analysis	YES
5441045	28546860	ET	2	contributed to the study design|contributed to the statistical analysis|contributed to the data interpretation|contributed to the draft of the manuscript	contributed to the draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
5441045	28546860	JB	2	contributed to the study design|contributed to the data collection|contributed to the data interpretation|contributed to the draft of the manuscript	contributed to the study design	Conceived and designed the experiments	Methodology	YES
5441045	28546860	JB	2	contributed to the study design|contributed to the data collection|contributed to the data interpretation|contributed to the draft of the manuscript	contributed to the data collection	Performed the experiments	Investigation	YES
5441045	28546860	JB	2	contributed to the study design|contributed to the data collection|contributed to the data interpretation|contributed to the draft of the manuscript	contributed to the data interpretation	Analyzed the data	Formal analysis	YES
5441045	28546860	JB	2	contributed to the study design|contributed to the data collection|contributed to the data interpretation|contributed to the draft of the manuscript	contributed to the draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
5441045	28546860	MB	2	contributed to the data interpretation	contributed to the data interpretation	Analyzed the data	Formal analysis	YES
3721469	23681698	BM	2	performed the sem	performed the sem	Performed the experiments	Investigation	YES
3721469	23681698	CC	2	designed the experiments|performed the experiments and analyzed the data	designed the experiments	Conceived and designed the experiments	Methodology	YES
3721469	23681698	CC	2	designed the experiments|performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3721469	23681698	CMP	2	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3721469	23681698	FG	2	provided valuable materials and conceptual input as well as edited the manuscript	provided valuable materials and conceptual input as well as edited the manuscript	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Resources|Writing - Review & Editing	YES
3721469	23681698	GMG	2	provided valuable materials and conceptual input as well as edited the manuscript	provided valuable materials and conceptual input as well as edited the manuscript	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Resources|Writing - Review & Editing	YES
3721469	23681698	LR	2	prepared the manuscript|designed the experiments	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
3721469	23681698	LR	2	prepared the manuscript|designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
3721469	23681698	NS	2	provided valuable materials and conceptual input as well as edited the manuscript	provided valuable materials and conceptual input as well as edited the manuscript	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Resources|Writing - Review & Editing	YES
3721469	23681698	SWH	2	prepared the manuscript|designed the experiments|performed the experiments and analyzed the data	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
3721469	23681698	SWH	2	prepared the manuscript|designed the experiments|performed the experiments and analyzed the data	designed the experiments	Conceived and designed the experiments	Methodology	YES
3721469	23681698	SWH	2	prepared the manuscript|designed the experiments|performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3721469	23681698	SYG	2	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5819190	29463214	AR	2	supervised the work	supervised the work	-	Supervision	YES
5819190	29463214	All authors	2	contributed to writing of the paper	contributed to writing of the paper	Wrote the paper	Writing - Original Draft	YES
5819190	29463214	CG	2	performed the bioinformatics survey	performed the bioinformatics survey	Performed the experiments	Formal analysis|Investigation	YES
5819190	29463214	NGC	2	supervised the work	supervised the work	-	Supervision	YES
5819190	29463214	TBO	2	planned the study, performed the bioinformatics survey, the data analysis and drafted the manuscript	planned the study, performed the bioinformatics survey, the data analysis and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
4659961	26640798	Sihai Zhao	2	contributed equally to this work	contributed equally to this work	-	-	NO
4659961	26640798	Yafeng Li	2	contributed equally to this work	contributed equally to this work	-	-	NO
5597732	28893932	E.L.	2	wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
5597732	28893932	K.-W.T.	2	wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
2020435	17957248	AW	PLoS5	Wrote the paper|Construction of dna microarray	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2020435	17957248	AW	PLoS5	Wrote the paper|Construction of dna microarray	Construction of dna microarray	Performed the experiments	Investigation	YES
2020435	17957248	AZ	PLoS5	Contributed reagents/materials/analysis tools|Establishment of dna microarray analysis	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2020435	17957248	AZ	PLoS5	Contributed reagents/materials/analysis tools|Establishment of dna microarray analysis	Establishment of dna microarray analysis	Performed the experiments	Investigation	YES
2020435	17957248	DO	PLoS5	Conceived and designed the experiments|Initiated the project|Supervised the project	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2020435	17957248	DO	PLoS5	Conceived and designed the experiments|Initiated the project|Supervised the project	Initiated the project	Conceived and designed the experiments	Conceptualization	YES
2020435	17957248	DO	PLoS5	Conceived and designed the experiments|Initiated the project|Supervised the project	Supervised the project	-	Supervision	YES
2020435	17957248	FP	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2020435	17957248	GW	PLoS5	Analyzed the data|Wrote the paper|Wrote algorithms for data processing and statistical analysis	Analyzed the data	Analyzed the data	Formal analysis	YES
2020435	17957248	GW	PLoS5	Analyzed the data|Wrote the paper|Wrote algorithms for data processing and statistical analysis	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2020435	17957248	GW	PLoS5	Analyzed the data|Wrote the paper|Wrote algorithms for data processing and statistical analysis	Wrote algorithms for data processing and statistical analysis	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Data curation|Formal analysis|Software|Writing - Original Draft	YES
2020435	17957248	JS	PLoS5	Initiated the project	Initiated the project	Conceived and designed the experiments	Conceptualization	YES
2020435	17957248	JT	PLoS5	Conceived and designed the experiments|Performed the experiments|Construction of dna microarray|Establishment of dna microarray analysis	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2020435	17957248	JT	PLoS5	Conceived and designed the experiments|Performed the experiments|Construction of dna microarray|Establishment of dna microarray analysis	Performed the experiments	Performed the experiments	Investigation	YES
2020435	17957248	JT	PLoS5	Conceived and designed the experiments|Performed the experiments|Construction of dna microarray|Establishment of dna microarray analysis	Construction of dna microarray	Performed the experiments	Investigation	YES
2020435	17957248	JT	PLoS5	Conceived and designed the experiments|Performed the experiments|Construction of dna microarray|Establishment of dna microarray analysis	Establishment of dna microarray analysis	Performed the experiments	Investigation	YES
2020435	17957248	JW	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2020435	17957248	MP	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5835327	29535755	AP	7	Worked on the mineral and statistical analysis	Worked on the mineral and statistical analysis	Performed the experiments|Analyzed the data	Formal analysis	YES
5835327	29535755	CE-N	7	Was responsible for the greenhouse tasks	Was responsible for the greenhouse tasks	-	-	NO
5835327	29535755	GC	7	Contributed in writing and improving the manuscript	Contributed in writing and improving the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5835327	29535755	GR	7	Had the original idea on testing omeprazole on vegetable crops and contributed in the set up of the experimental protocol	Had the original idea on testing omeprazole on vegetable crops and contributed in the set up of the experimental protocol	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
5835327	29535755	LL	7	Performed the whole the metabolomic analysis, and gave an important contribution on metabolomic results interpretation as well as a significant contribution in writing the manuscript	Performed the whole the metabolomic analysis, and gave an important contribution on metabolomic results interpretation as well as a significant contribution in writing the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5835327	29535755	MK	7	Contributed in writing and improving the manuscript	Contributed in writing and improving the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5835327	29535755	PC	7	Contributed in writing the physiological and ion analyses parts and run the pca and heat map	Contributed in writing the physiological and ion analyses parts and run the pca and heat map	Analyzed the data|Wrote the paper	Formal analysis	YES
5835327	29535755	SDP	7	Contributed in writing and improving the manuscript	Contributed in writing and improving the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5835327	29535755	VC	7	Worked on the mineral and statistical analysis	Worked on the mineral and statistical analysis	Performed the experiments|Analyzed the data	Formal analysis	YES
5835327	29535755	YR	7	Defined the scientific hypothesis, set up the experimental protocol, coordinated the research and he was significantly involved in writing	Defined the scientific hypothesis, set up the experimental protocol, coordinated the research and he was significantly involved in writing	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Methodology|Project administration	YES
4418734	25938415	CCY	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418734	25938415	CHC	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418734	25938415	CHL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418734	25938415	CYK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418734	25938415	MSL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4418734	25938415	MSL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418734	25938415	SMC	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418734	25938415	SMC	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418734	25938415	YSH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418734	25938415	ZFW	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418734	25938415	ZFW	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418734	25938415	ZFW	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5446746	28560042	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5446746	28560042	BSA	2	supported the work with their expertise	supported the work with their expertise	-	-	NO
5446746	28560042	DH	2	performed the data collection of the dependent variable	performed the data collection of the dependent variable	Performed the experiments	Investigation	YES
5446746	28560042	FR	2	supported the work with their expertise	supported the work with their expertise	-	-	NO
5446746	28560042	JS	2	supported the work with their expertise	supported the work with their expertise	-	-	NO
5446746	28560042	MH	2	was the project leader	was the project leader	-	Supervision	YES
5446746	28560042	MJ	2	designed the study, performed the data collection, analysis, and interpretation and was the major contributor in writing this manuscript	designed the study, performed the data collection, analysis, and interpretation and was the major contributor in writing this manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5446746	28560042	SK	2	enabled the patient enrolment	enabled the patient enrolment	-	-	NO
5446746	28560042	SS	2	supported the work with their expertise	supported the work with their expertise	-	-	NO
5446746	28560042	WE	2	supported the work with his expertise and helped write this manuscript	supported the work with his expertise and helped write this manuscript	Wrote the paper	Writing - Original Draft	YES
6270868	24651611	All authors	2	have contributed to, seen and approved the manuscript	have contributed to, seen and approved the manuscript	-	-	NO
6270868	24651611	Cheng-Jun Shi	2	designed methods and experiments, carried out the laboratory experiments, analyzed the data, interpreted the results and wrote the paper	designed methods and experiments, carried out the laboratory experiments, analyzed the data, interpreted the results and wrote the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
6270868	24651611	Fang Wang	2	designed methods and experiments, carried out the laboratory experiments, analyzed the data, interpreted the results and wrote the paper	designed methods and experiments, carried out the laboratory experiments, analyzed the data, interpreted the results and wrote the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
6270868	24651611	Hui Zhang	2	co-designed experiments, discussed analyses, interpretation, and presentation	co-designed experiments, discussed analyses, interpretation, and presentation	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
6270868	24651611	Li-Wu Fu	2	defined the research theme	defined the research theme	-	-	NO
6270868	24651611	Xiao-Kun Wang	2	designed methods and experiments, carried out the laboratory experiments, analyzed the data, interpreted the results and wrote the paper	designed methods and experiments, carried out the laboratory experiments, analyzed the data, interpreted the results and wrote the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
6270868	24651611	Ya-Peng Hu	2	co-designed experiments, discussed analyses, interpretation, and presentation	co-designed experiments, discussed analyses, interpretation, and presentation	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
6270868	24651611	Yi-Fan Chen	2	co-designed experiments, discussed analyses, interpretation, and presentation	co-designed experiments, discussed analyses, interpretation, and presentation	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
4289851	25578979	AP	2	surgical specimens providing	surgical specimens providing	Performed the experiments	Investigation	YES
4289851	25578979	AS	2	cell isolation, primary cultures and qpcr performing	cell isolation, primary cultures and qpcr performing	Performed the experiments	Investigation	YES
4289851	25578979	AV	2	immunochemical analysis performing	immunochemical analysis performing	Performed the experiments	Investigation	YES
4289851	25578979	CS	2	study design and coordination, manuscript drafting	study design and coordination, manuscript drafting	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft	YES
4289851	25578979	EC	2	study supervision, critical manuscript revision for important intellectual content	study supervision, critical manuscript revision for important intellectual content	Wrote the paper	Supervision|Writing - Review & Editing	YES
4289851	25578979	EG	2	study supervision, critical manuscript revision for important intellectual content	study supervision, critical manuscript revision for important intellectual content	Wrote the paper	Supervision|Writing - Review & Editing	YES
4289851	25578979	GD	2	surgical specimens providing	surgical specimens providing	Performed the experiments	Investigation	YES
4289851	25578979	NP	2	participation in the study design and manuscript revision	participation in the study design and manuscript revision	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
4289851	25578979	PA	2	study design and coordination, manuscript drafting	study design and coordination, manuscript drafting	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft	YES
4289851	25578979	RC	2	surgical specimens providing	surgical specimens providing	Performed the experiments	Investigation	YES
4289851	25578979	RS	2	immunochemical analysis performing	immunochemical analysis performing	Performed the experiments	Investigation	YES
3721470	23723167	AS	7	acquisition of data	acquisition of data	Performed the experiments	Investigation	YES
3721470	23723167	CL	7	study supervision, obtained funding, critical revision of the manuscript for important intellectual content	study supervision, obtained funding, critical revision of the manuscript for important intellectual content	Wrote the paper	Funding acquisition|Supervision|Writing - Review & Editing	YES
3721470	23723167	CLO	7	material support	material support	-	-	NO
3721470	23723167	ED	7	acquisition of data, critical revision of the manuscript for important intellectual content	acquisition of data, critical revision of the manuscript for important intellectual content	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
3721470	23723167	EVW	7	acquisition of data	acquisition of data	Performed the experiments	Investigation	YES
3721470	23723167	FVH	7	acquisition of data, critical revision of the manuscript for important intellectual content	acquisition of data, critical revision of the manuscript for important intellectual content	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
3721470	23723167	KG	7	material and technical support	material and technical support	Performed the experiments	Investigation	YES
3721470	23723167	RDR	7	acquisition of data	acquisition of data	Performed the experiments	Investigation	YES
3721470	23723167	REV	7	study concept and design, acquisition of data, analysis and interpretation of data, drafting of the manuscript, critical revision of the manuscript for important intellectual content, obtained funding	study concept and design, acquisition of data, analysis and interpretation of data, drafting of the manuscript, critical revision of the manuscript for important intellectual content, obtained funding	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Funding acquisition|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
3721470	23723167	SL	7	acquisition of data	acquisition of data	Performed the experiments	Investigation	YES
6015586	29936607	AJ	1	Experiment planning and design	Experiment planning and design	Conceived and designed the experiments	Methodology	YES
6015586	29936607	WNC	1	Experiment planning and design	Experiment planning and design	Conceived and designed the experiments	Methodology	YES
6015586	29936607	XHL	1	Experiment planning and design	Experiment planning and design	Conceived and designed the experiments	Methodology	YES
4659962	26640797	Angela Flavia Logullo	2	participated in the writing of the paper	participated in the writing of the paper	Wrote the paper	Writing - Original Draft	YES
4659962	26640797	Dan Linetzky Waitzberg	2	contributed to the conception of the research and reviewing of the paper	contributed to the conception of the research and reviewing of the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
4659962	26640797	Graziela Rosa Ravacci	2	was responsible for the conception, design, acquisition, and analysis of data, interpretation of the results, and drafting of the paper	was responsible for the conception, design, acquisition, and analysis of data, interpretation of the results, and drafting of the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
4659962	26640797	Jessica Reis Santos	2	participated in the writing of the paper	participated in the writing of the paper	Wrote the paper	Writing - Original Draft	YES
4659962	26640797	M. M. Torrinhas	2	participated in the writing of the paper	participated in the writing of the paper	Wrote the paper	Writing - Original Draft	YES
4659962	26640797	Maria Mitzi Brentani	2	contributed to the conception and design of the research, reviewing of the paper, and interpretation of the results	contributed to the conception and design of the research, reviewing of the paper, and interpretation of the results	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Review & Editing	YES
4659962	26640797	Raquel Suzana	2	participated in the writing of the paper	participated in the writing of the paper	Wrote the paper	Writing - Original Draft	YES
4659962	26640797	Tharcisio Citrangulo Tortelli	2	was responsible for the acquisition and analysis of data and reviewing of the paper	was responsible for the acquisition and analysis of data and reviewing of the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
5597738	28893938	A.B.R.	2	wrote this review	wrote this review	Wrote the paper	Writing - Original Draft	YES
5597738	28893938	A.I.B.	2	wrote this review	wrote this review	Wrote the paper	Writing - Original Draft	YES
5597738	28893938	C.S.-L.	2	wrote this review	wrote this review	Wrote the paper	Writing - Original Draft	YES
4418735	25938506	MIMH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418735	25938506	MIMH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418735	25938506	MIMH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418735	25938506	MIMH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418735	25938506	MIMH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418735	25938506	PGS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418735	25938506	PGS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418735	25938506	PGS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418735	25938506	PGS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418735	25938506	PGS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2020436	17957249	AJ	PLoS5	Developed the c programs	Developed the c programs	-	Software	YES
2020436	17957249	HA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Developed the c programs	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2020436	17957249	HA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Developed the c programs	Analyzed the data	Analyzed the data	Formal analysis	YES
2020436	17957249	HA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Developed the c programs	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2020436	17957249	HA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Developed the c programs	Developed the c programs	-	Software	YES
2020436	17957249	PG	PLoS5	Conceived and designed the experiments|Analyzed the data|Developed the c programs	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2020436	17957249	PG	PLoS5	Conceived and designed the experiments|Analyzed the data|Developed the c programs	Analyzed the data	Analyzed the data	Formal analysis	YES
2020436	17957249	PG	PLoS5	Conceived and designed the experiments|Analyzed the data|Developed the c programs	Developed the c programs	-	Software	YES
5835344	29535757	BS	PLoS52	analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5835344	29535757	BS	PLoS52	analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5835344	29535757	WS	PLoS52	designed the experiment|wrote the manuscript	designed the experiment	Conceived and designed the experiments	Methodology	YES
5835344	29535757	WS	PLoS52	designed the experiment|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5835344	29535757	YW	PLoS52	designed the experiment	designed the experiment	Conceived and designed the experiments	Methodology	YES
5819264	29458326	EH	7	Analyzed the data, interpreted the results, and prepared figures for the paper	Analyzed the data, interpreted the results, and prepared figures for the paper	Analyzed the data|Wrote the paper	Formal analysis|Visualization|Writing - Original Draft	YES
5819264	29458326	GS	7	Performed the experiments, analyzed the data, interpreted the results, and prepared figures for the paper	Performed the experiments, analyzed the data, interpreted the results, and prepared figures for the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Visualization|Writing - Original Draft	YES
5819264	29458326	KK	7	Designed the analysis, analyzed the data, and prepared tables for the paper	Designed the analysis, analyzed the data, and prepared tables for the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5819264	29458326	SO	7	Analyzed the data, interpreted the results, and prepared figures for the paper	Analyzed the data, interpreted the results, and prepared figures for the paper	Analyzed the data|Wrote the paper	Formal analysis|Visualization|Writing - Original Draft	YES
5819264	29458326	YO	7	Conceived of and designed the study, and wrote the paper	Conceived of and designed the study, and wrote the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
5819264	29458326	YW	7	Analyzed the data and prepared figures for the paper	Analyzed the data and prepared figures for the paper	Analyzed the data|Wrote the paper	Formal analysis|Visualization|Writing - Original Draft	YES
3721471	23733368	AL	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
3721471	23733368	DB	2	supervised jlz and provided reagents	supervised jlz and provided reagents	Contributed reagents/materials/analysis tools	Resources|Supervision	YES
3721471	23733368	EB	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
3721471	23733368	HSC	2	designed and performed experiments, and analysed data	designed and performed experiments, and analysed data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
3721471	23733368	JEF	2	designed and performed experiments, analysed data and wrote the manuscript	designed and performed experiments, analysed data and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
3721471	23733368	JLZ	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
3721471	23733368	MIC	2	supervised al and designed experiments	supervised al and designed experiments	Conceived and designed the experiments	Methodology|Supervision	YES
3721471	23733368	NS	2	designed and performed experiments, and analysed data	designed and performed experiments, and analysed data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
3721471	23733368	PDO	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
6020087	29943167	ACFO	PLoS52	performed the research	performed the research	Performed the experiments	Investigation	YES
6020087	29943167	All	PLoS52	data analyzed in this article are included in the figures and tables	data analyzed in this article are included in the figures and tables	Analyzed the data	Formal analysis|Visualization	YES
6020087	29943167	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6020087	29943167	JGLFA	PLoS52	designed the experiments and analyzed the data	designed the experiments and analyzed the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
6020087	29943167	MTN	PLoS52	performed the research|wrote the paper	performed the research	Performed the experiments	Investigation	YES
6020087	29943167	MTN	PLoS52	performed the research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6020087	29943167	OLMB	PLoS52	polished the manuscript	polished the manuscript	Wrote the paper	Writing - Review & Editing	YES
6020087	29943167	PSM	PLoS52	polished the manuscript	polished the manuscript	Wrote the paper	Writing - Review & Editing	YES
6020087	29943167	RHP	PLoS52	designed the experiments and analyzed the data	designed the experiments and analyzed the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
6020087	29943167	The authors	PLoS52	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5597739	28893939	C.R.M.B.	2	performed the literature review, wrote and revised the article	performed the literature review, wrote and revised the article	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5597739	28893939	M.M.	2	performed the literature review, wrote and revised the article	performed the literature review, wrote and revised the article	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
2020437	17957251	HM	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
2020437	17957251	HM	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2020437	17957251	JZ	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
2020437	17957251	JZ	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2020437	17957251	LM	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
2020437	17957251	LM	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2020437	17957251	PC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Paradigm	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2020437	17957251	PC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Paradigm	Analyzed the data	Analyzed the data	Formal analysis	YES
2020437	17957251	PC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Paradigm	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2020437	17957251	PC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Paradigm	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2020437	17957251	PC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Paradigm	Paradigm	-	-	NO
2020437	17957251	SS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
2020437	17957251	SS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2020437	17957251	TY	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
2020437	17957251	VP	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
2020437	17957251	VP	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2020437	17957251	YH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
2020437	17957251	YY	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
2020437	17957251	YY	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5819297	29458329	DO	2	carried out all the bioinformatics analysis	carried out all the bioinformatics analysis	Performed the experiments	Formal analysis|Investigation	YES
5819297	29458329	EC	2	carried out the library preparation and sequencing	carried out the library preparation and sequencing	Performed the experiments	Investigation	YES
5819297	29458329	IK	2	carried out chromocenters dna isolation and all fish experiments	carried out chromocenters dna isolation and all fish experiments	Performed the experiments	Investigation	YES
5819297	29458329	OP	2	was responsible for the work managing and text preparation	was responsible for the work managing and text preparation	-	-	NO
5450202	28572979	MT	2	provided intellectual input and helped to draft and revise the manuscript	provided intellectual input and helped to draft and revise the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5450202	28572979	YI	2	drafted and revised the manuscript	drafted and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5835670	29541086	JG	PLoS52	conducted the experiments|wrote the manuscript	conducted the experiments	Performed the experiments	Investigation	YES
5835670	29541086	JG	PLoS52	conducted the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5835670	29541086	JY	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5835670	29541086	KG	PLoS52	conducted the experiments	conducted the experiments	Performed the experiments	Investigation	YES
5835670	29541086	MZ	PLoS52	conducted the experiments	conducted the experiments	Performed the experiments	Investigation	YES
5835670	29541086	SH	PLoS52	conducted the experiments|analyzed the data	conducted the experiments	Performed the experiments	Investigation	YES
5835670	29541086	SH	PLoS52	conducted the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5835670	29541086	SY	PLoS52	conducted the experiments	conducted the experiments	Performed the experiments	Investigation	YES
5835670	29541086	YL	PLoS52	conducted the experiments	conducted the experiments	Performed the experiments	Investigation	YES
5835670	29541086	ZY	PLoS52	designed the research and revised the manuscript	designed the research and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
4418738	25938237	CCS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418738	25938237	CKL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418738	25938237	CKL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418738	25938237	CKL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418738	25938237	CTC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418738	25938237	CTC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418738	25938237	CTC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418738	25938237	CTC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418738	25938237	GMJ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418738	25938237	HSW	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418738	25938237	JCW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418738	25938237	JCW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418738	25938237	JCW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418738	25938237	TKT	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
6270869	25493631	All authors	2	conducted literature search and contributed to the sections on their specialty	conducted literature search and contributed to the sections on their specialty	Performed the experiments	Formal analysis|Investigation	YES
6270869	25493631	H.F.	2	cancer applications	cancer applications	-	-	NO
6270869	25493631	L.S.	2	membrane interactions	membrane interactions	-	-	NO
6270869	25493631	M.Z.	2	structured and supervised the manuscript|molecular modeling of dendrimers	structured and supervised the manuscript	-	Supervision	YES
6270869	25493631	M.Z.	2	structured and supervised the manuscript|molecular modeling of dendrimers	molecular modeling of dendrimers	Performed the experiments	Investigation|Methodology	YES
6270869	25493631	N.M.	2	wrote the paper and conducted the main literature search	wrote the paper and conducted the main literature search	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6270869	25493631	S.B.	2	dendrimers chemistry	dendrimers chemistry	-	-	NO
6270869	25493631	T.B.	2	structured and supervised the manuscript|molecular modeling of dendrimers	structured and supervised the manuscript	-	Supervision	YES
6270869	25493631	T.B.	2	structured and supervised the manuscript|molecular modeling of dendrimers	molecular modeling of dendrimers	Performed the experiments	Investigation|Methodology	YES
2020438	17957240	ES	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Initiator and coordinator of the study	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2020438	17957240	ES	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Initiator and coordinator of the study	Analyzed the data	Analyzed the data	Formal analysis	YES
2020438	17957240	ES	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Initiator and coordinator of the study	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2020438	17957240	ES	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Initiator and coordinator of the study	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2020438	17957240	ES	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Initiator and coordinator of the study	Initiator and coordinator of the study	-	Project administration	YES
2020438	17957240	HL	PLoS5	Analyzed the data|Designed and supervised the ros experiments	Analyzed the data	Analyzed the data	Formal analysis	YES
2020438	17957240	HL	PLoS5	Analyzed the data|Designed and supervised the ros experiments	Designed and supervised the ros experiments	Conceived and designed the experiments	Methodology|Supervision	YES
2020438	17957240	IB	PLoS5	Performed the experiments|Analyzed the data|Took part in the preparation of the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
2020438	17957240	IB	PLoS5	Performed the experiments|Analyzed the data|Took part in the preparation of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
2020438	17957240	IB	PLoS5	Performed the experiments|Analyzed the data|Took part in the preparation of the manuscript	Took part in the preparation of the manuscript	Wrote the paper	Writing - Original Draft	YES
2020438	17957240	JN	PLoS5	Analyzed the data|Responsible for visits of patients and control persons, including anamnesis and physical examination|Performed statistical analyses	Analyzed the data	Analyzed the data	Formal analysis	YES
2020438	17957240	JN	PLoS5	Analyzed the data|Responsible for visits of patients and control persons, including anamnesis and physical examination|Performed statistical analyses	Responsible for visits of patients and control persons, including anamnesis and physical examination	Performed the experiments	Investigation	YES
2020438	17957240	JN	PLoS5	Analyzed the data|Responsible for visits of patients and control persons, including anamnesis and physical examination|Performed statistical analyses	Performed statistical analyses	Analyzed the data	Formal analysis	YES
2020438	17957240	LJ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Responsible for the clinical part of the study	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2020438	17957240	LJ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Responsible for the clinical part of the study	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2020438	17957240	LJ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Responsible for the clinical part of the study	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2020438	17957240	LJ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Responsible for the clinical part of the study	Responsible for the clinical part of the study	-	-	NO
2020438	17957240	VP	PLoS5	Performed the experiments|Analyzed the data|Supervised some of the experiments|Took part in the preparation of the manuscript|Performed statistical analyses	Performed the experiments	Performed the experiments	Investigation	YES
2020438	17957240	VP	PLoS5	Performed the experiments|Analyzed the data|Supervised some of the experiments|Took part in the preparation of the manuscript|Performed statistical analyses	Analyzed the data	Analyzed the data	Formal analysis	YES
2020438	17957240	VP	PLoS5	Performed the experiments|Analyzed the data|Supervised some of the experiments|Took part in the preparation of the manuscript|Performed statistical analyses	Supervised some of the experiments	-	Supervision	YES
2020438	17957240	VP	PLoS5	Performed the experiments|Analyzed the data|Supervised some of the experiments|Took part in the preparation of the manuscript|Performed statistical analyses	Took part in the preparation of the manuscript	Wrote the paper	Writing - Original Draft	YES
2020438	17957240	VP	PLoS5	Performed the experiments|Analyzed the data|Supervised some of the experiments|Took part in the preparation of the manuscript|Performed statistical analyses	Performed statistical analyses	Analyzed the data	Formal analysis	YES
3721472	23681607	All authors	PLoS52	analyzed data and contributed to manuscript editing	analyzed data and contributed to manuscript editing	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
3721472	23681607	CB	PLoS52	designed the study|performed experiments|wrote the paper	designed the study	Conceived and designed the experiments	Methodology	YES
3721472	23681607	CB	PLoS52	designed the study|performed experiments|wrote the paper	performed experiments	Performed the experiments	Investigation	YES
3721472	23681607	CB	PLoS52	designed the study|performed experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3721472	23681607	DEZ	PLoS52	designed the study|wrote the paper	designed the study	Conceived and designed the experiments	Methodology	YES
3721472	23681607	DEZ	PLoS52	designed the study|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3721472	23681607	KA	PLoS52	performed experiments	performed experiments	Performed the experiments	Investigation	YES
3721472	23681607	LGE	PLoS52	designed the study|critically reviewed the data and gave feedback	designed the study	Conceived and designed the experiments	Methodology	YES
3721472	23681607	LGE	PLoS52	designed the study|critically reviewed the data and gave feedback	critically reviewed the data and gave feedback	-	-	NO
3721472	23681607	NX	PLoS52	performed experiments	performed experiments	Performed the experiments	Investigation	YES
3721472	23681607	SVK	PLoS52	critically reviewed the data and gave feedback	critically reviewed the data and gave feedback	-	-	NO
3721472	23681607	TT	PLoS52	performed experiments	performed experiments	Performed the experiments	Investigation	YES
3721472	23681607	XC	PLoS52	performed experiments	performed experiments	Performed the experiments	Investigation	YES
3721472	23681607	YCL	PLoS52	critically reviewed the data and gave feedback	critically reviewed the data and gave feedback	-	-	NO
5835687	29541079	All authors	2	approved the manuscript	approved the manuscript	-	-	NO
6026486	29961200	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6026486	29961200	DZ	2	supervised all experiments and review of manuscript	supervised all experiments and review of manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
6026486	29961200	FC	2	assisted in conducting experiments	assisted in conducting experiments	Performed the experiments	Investigation	YES
6026486	29961200	LZ	2	participated in microbial data analysis and the manuscript editing	participated in microbial data analysis and the manuscript editing	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
6026486	29961200	PL	2	guided research work	guided research work	Performed the experiments	Investigation|Supervision	YES
6026486	29961200	WL	2	conducted the research work and drafted manuscript	conducted the research work and drafted manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6026486	29961200	XH	2	participated in microbial data analysis and the manuscript editing	participated in microbial data analysis and the manuscript editing	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
5819677	29463212	AB	2	provided critical guidance and advice with the positive selection analysis	provided critical guidance and advice with the positive selection analysis	-	Supervision	YES
5819677	29463212	ALR	2	performed the rna seq differential expression bioinformatics and statistics	performed the rna seq differential expression bioinformatics and statistics	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5819677	29463212	CLR	2	performed the embryo anoxia treatments, collected and extracted total rna from the embryos, and prepared the poly-a libraries for sequencing	performed the embryo anoxia treatments, collected and extracted total rna from the embryos, and prepared the poly-a libraries for sequencing	Performed the experiments	Investigation	YES
5819677	29463212	GBLOCKS	2	positive selection analysis	positive selection analysis	-	-	NO
5819677	29463212	GO	2	term enrichment and rna seq results, performed the protein clustering with proteinortho, constructed the phylogenetic tree, performed the flow cytometry genome size estimate, and prepared the manuscript|term enrichment statistics, and provided the alignment for phylogenetic tree inference	term enrichment and rna seq results, performed the protein clustering with proteinortho, constructed the phylogenetic tree, performed the flow cytometry genome size estimate, and prepared the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5819677	29463212	GO	2	term enrichment and rna seq results, performed the protein clustering with proteinortho, constructed the phylogenetic tree, performed the flow cytometry genome size estimate, and prepared the manuscript|term enrichment statistics, and provided the alignment for phylogenetic tree inference	term enrichment statistics, and provided the alignment for phylogenetic tree inference	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5819677	29463212	GUIDANCE	2	positive selection analysis	positive selection analysis	-	-	NO
5819677	29463212	JR	2	assisted with summarizing and interpreting the hsp gene abundance data	assisted with summarizing and interpreting the hsp gene abundance data	Analyzed the data	Formal analysis	YES
5819677	29463212	NCBI	2	for annotation	for annotation	Analyzed the data	Data curation|Formal analysis	YES
5819677	29463212	PAML	2	positive selection analysis	positive selection analysis	-	-	NO
5819677	29463212	SCW	2	assisted with organizing the go term enrichment results and summarizing the rna seq differential expression results	assisted with organizing the go term enrichment results and summarizing the rna seq differential expression results	Performed the experiments	Investigation	YES
5819677	29463212	SSPACE	2	performed cegma and busco analyses, interpreted the paml	performed cegma and busco analyses, interpreted the paml	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5819677	29463212	W. All	2	authors contributed writing to their respective sections and provided feedback for revisions on the manuscript	authors contributed writing to their respective sections and provided feedback for revisions on the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5819677	29463212	WW	2	provided critical oversight of the assembly improvement steps	provided critical oversight of the assembly improvement steps	-	Supervision	YES
4662965	26649297	Xiao-Min Hu	2	contributed equally to this work	contributed equally to this work	-	-	NO
4662965	26649297	Yan-Rui Xu	2	contributed equally to this work	contributed equally to this work	-	-	NO
5450244	28572981	JT	2	had the concept|helped in the editing	had the concept	Conceived and designed the experiments	Conceptualization	YES
5450244	28572981	JT	2	had the concept|helped in the editing	helped in the editing	Wrote the paper	Writing - Review & Editing	YES
5450244	28572981	TI	2	had the concept	had the concept	Conceived and designed the experiments	Conceptualization	YES
2020439	17957241	BD	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2020439	17957241	CA	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2020439	17957241	IC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2020439	17957241	IC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2020439	17957241	IC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2020439	17957241	IC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2020439	17957241	MT	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2020439	17957241	NS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
2020439	17957241	NS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2020439	17957241	PS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418739	25938513	AM	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418739	25938513	FB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418739	25938513	GF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418739	25938513	GF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418739	25938513	GF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418739	25938513	JCS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418739	25938513	JCS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418739	25938513	JCS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418739	25938513	MV	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418739	25938513	NP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418739	25938513	NP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418739	25938513	NP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418739	25938513	NP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418739	25938513	PC	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418739	25938513	SB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418739	25938513	SB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418739	25938513	SB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418739	25938513	SB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418739	25938513	SO	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418739	25938513	TC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418739	25938513	TC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418739	25938513	TC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418739	25938513	VG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418739	25938513	VG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418739	25938513	VG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418739	25938513	VV	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4378210	25820556	All authors	2	have reviewed and contributed to the different draft versions of the manuscript and have read and approved the final manuscript	have reviewed and contributed to the different draft versions of the manuscript and have read and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4378210	25820556	IT	2	experimental procedures, immunohistochemical processing, microscopic analysis, data collection and/or preparation of figures	experimental procedures, immunohistochemical processing, microscopic analysis, data collection and/or preparation of figures	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation|Visualization	YES
4378210	25820556	KO	2	study design|experimental procedures, immunohistochemical processing, microscopic analysis, data collection and/or preparation of figures|contribution to real time pcr analysis	study design	Conceived and designed the experiments	Methodology	YES
4378210	25820556	KO	2	study design|experimental procedures, immunohistochemical processing, microscopic analysis, data collection and/or preparation of figures|contribution to real time pcr analysis	experimental procedures, immunohistochemical processing, microscopic analysis, data collection and/or preparation of figures	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation|Visualization	YES
4378210	25820556	KO	2	study design|experimental procedures, immunohistochemical processing, microscopic analysis, data collection and/or preparation of figures|contribution to real time pcr analysis	contribution to real time pcr analysis	Performed the experiments	Investigation	YES
4378210	25820556	NK	2	experimental procedures, immunohistochemical processing, microscopic analysis, data collection and/or preparation of figures	experimental procedures, immunohistochemical processing, microscopic analysis, data collection and/or preparation of figures	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation|Visualization	YES
4378210	25820556	SF	2	study design	study design	Conceived and designed the experiments	Methodology	YES
4378210	25820556	YS	2	experimental procedures, immunohistochemical processing, microscopic analysis, data collection and/or preparation of figures	experimental procedures, immunohistochemical processing, microscopic analysis, data collection and/or preparation of figures	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation|Visualization	YES
5835688	29541082	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5835688	29541082	LS	2	performed experiments, analyzed and interpreted the data, and wrote the manuscript|revised the manuscript critically	performed experiments, analyzed and interpreted the data, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5835688	29541082	LS	2	performed experiments, analyzed and interpreted the data, and wrote the manuscript|revised the manuscript critically	revised the manuscript critically	Wrote the paper	Writing - Review & Editing	YES
5835688	29541082	SC	2	performed experiments, analyzed and interpreted the data, and wrote the manuscript|revised the manuscript critically	performed experiments, analyzed and interpreted the data, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5835688	29541082	SC	2	performed experiments, analyzed and interpreted the data, and wrote the manuscript|revised the manuscript critically	revised the manuscript critically	Wrote the paper	Writing - Review & Editing	YES
5835688	29541082	WC	2	performed experiments, analyzed and interpreted the data, and wrote the manuscript	performed experiments, analyzed and interpreted the data, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5835688	29541082	XC	2	performed experiments, analyzed and interpreted the data, and wrote the manuscript	performed experiments, analyzed and interpreted the data, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5835688	29541082	YZ	2	conceived and designed the study|revised the manuscript critically	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5835688	29541082	YZ	2	conceived and designed the study|revised the manuscript critically	revised the manuscript critically	Wrote the paper	Writing - Review & Editing	YES
5835688	29541082	ZY	2	conceived and designed the study|revised the manuscript critically	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5835688	29541082	ZY	2	conceived and designed the study|revised the manuscript critically	revised the manuscript critically	Wrote the paper	Writing - Review & Editing	YES
5597741	28893941	J.A.M.	2	contributed to conception of the article, drafted the article, revised it critically for important intellectual content and approved the final version	contributed to conception of the article, drafted the article, revised it critically for important intellectual content and approved the final version	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
5597741	28893941	M.R.	2	contributed to conception of the article, drafted the article, revised it critically for important intellectual content and approved the final version	contributed to conception of the article, drafted the article, revised it critically for important intellectual content and approved the final version	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
5597741	28893941	U.P.	2	contributed to conception of the article, drafted the article, revised it critically for important intellectual content and approved the final version	contributed to conception of the article, drafted the article, revised it critically for important intellectual content and approved the final version	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
2020440	17957242	FK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2020440	17957242	FK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
2020440	17957242	FK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2020440	17957242	HK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2020440	17957242	HK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2020440	17957242	HK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2020440	17957242	KH	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2020440	17957242	KN	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2020440	17957242	KN	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2020440	17957242	KT	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2020440	17957242	NH	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2020440	17957242	NK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2020440	17957242	NK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2020440	17957242	NK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2020440	17957242	NK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2020440	17957242	NO	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2020440	17957242	SO	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
2020440	17957242	ST	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
2020440	17957242	ST	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2020440	17957242	TA	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2020440	17957242	TA	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2020440	17957242	TI	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
2020440	17957242	TI	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2020440	17957242	TK	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2020440	17957242	TS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
2020440	17957242	UC	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2020440	17957242	UC	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2020440	17957242	WC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2020440	17957242	YA	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
2020440	17957242	YK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
2020440	17957242	YO	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
2020440	17957242	YO	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2020440	17957242	YS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
3721473	23666744	BCG	PLoS52	devised the project and obtained funding	devised the project and obtained funding	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
3721473	23666744	BD	PLoS52	provided oslo ovarian cancer samples	provided oslo ovarian cancer samples	Contributed reagents/materials/analysis tools	Resources	YES
3721473	23666744	IK	PLoS52	provided ovarian cancer cell lines	provided ovarian cancer cell lines	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
3721473	23666744	JAL	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
3721473	23666744	JMN	PLoS52	provided oslo ovarian cancer samples	provided oslo ovarian cancer samples	Contributed reagents/materials/analysis tools	Resources	YES
3721473	23666744	JPT	PLoS52	devised the project and obtained funding|wrote the paper	devised the project and obtained funding	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
3721473	23666744	JPT	PLoS52	devised the project and obtained funding|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3721473	23666744	JTC	PLoS52	wrote the paper|performed bioinformatics analyses	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3721473	23666744	JTC	PLoS52	wrote the paper|performed bioinformatics analyses	performed bioinformatics analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3721473	23666744	JY	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
3721473	23666744	LHBAH	PLoS52	performed next-generation sequencing analysis	performed next-generation sequencing analysis	Performed the experiments	Investigation	YES
3721473	23666744	LZW	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
3721473	23666744	MC	PLoS52	performed clinical parameter analyses	performed clinical parameter analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3721473	23666744	MCW	PLoS52	performed next-generation sequencing analysis	performed next-generation sequencing analysis	Performed the experiments	Investigation	YES
3721473	23666744	MKW	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
3721473	23666744	MM	PLoS52	provided ovarian cancer cell lines	provided ovarian cancer cell lines	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
3721473	23666744	NM	PLoS52	performed the experiments|provided ovarian cancer cell lines	performed the experiments	Performed the experiments	Investigation	YES
3721473	23666744	NM	PLoS52	performed the experiments|provided ovarian cancer cell lines	provided ovarian cancer cell lines	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
3721473	23666744	QHM	PLoS52	wrote the paper|performed the experiments	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3721473	23666744	QHM	PLoS52	wrote the paper|performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
3721473	23666744	RS	PLoS52	performed next-generation sequencing analysis	performed next-generation sequencing analysis	Performed the experiments	Investigation	YES
3721473	23666744	RYH	PLoS52	devised the project and obtained funding|wrote the paper	devised the project and obtained funding	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
3721473	23666744	RYH	PLoS52	devised the project and obtained funding|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3721473	23666744	SM	PLoS52	conceived the idea|devised the project and obtained funding|wrote the paper|performed the experiments|performed bioinformatics analyses	conceived the idea	Conceived and designed the experiments	Conceptualization	YES
3721473	23666744	SM	PLoS52	conceived the idea|devised the project and obtained funding|wrote the paper|performed the experiments|performed bioinformatics analyses	devised the project and obtained funding	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
3721473	23666744	SM	PLoS52	conceived the idea|devised the project and obtained funding|wrote the paper|performed the experiments|performed bioinformatics analyses	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3721473	23666744	SM	PLoS52	conceived the idea|devised the project and obtained funding|wrote the paper|performed the experiments|performed bioinformatics analyses	performed the experiments	Performed the experiments	Investigation	YES
3721473	23666744	SM	PLoS52	conceived the idea|devised the project and obtained funding|wrote the paper|performed the experiments|performed bioinformatics analyses	performed bioinformatics analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3721473	23666744	TZT	PLoS52	wrote the paper|performed bioinformatics analyses	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3721473	23666744	TZT	PLoS52	wrote the paper|performed bioinformatics analyses	performed bioinformatics analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5819699	29463232	B. Both	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5819699	29463232	BB	PLoS52	conceived of the project|wrote the paper	conceived of the project	Conceived and designed the experiments	Conceptualization	YES
5819699	29463232	BB	PLoS52	conceived of the project|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5819699	29463232	YO	PLoS52	conceived of the project|wrote the paper	conceived of the project	Conceived and designed the experiments	Conceptualization	YES
5819699	29463232	YO	PLoS52	conceived of the project|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6026487	29961206	AR	2	is equally contributed to this work by doing some experiments and analyzing the results and writing the draft of the manuscript	is equally contributed to this work by doing some experiments and analyzing the results and writing the draft of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6026487	29961206	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6026487	29961206	FR	2	collected and analyzed the bioinformatics data	collected and analyzed the bioinformatics data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6026487	29961206	GA	2	designed the experiments, supported the project, analyzed data and wrote the final manuscript	designed the experiments, supported the project, analyzed data and wrote the final manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
6026487	29961206	HF	2	conducted most of the experiments	conducted most of the experiments	Performed the experiments	Investigation	YES
6026487	29961206	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
6270871	25079660	All authors	2	discussed, edited and approved the final version	discussed, edited and approved the final version	Wrote the paper	Writing - Review & Editing	YES
6270871	25079660	H.C.H.	2	designed the research|performed the experimental work	designed the research	Conceived and designed the experiments	Methodology	YES
6270871	25079660	H.C.H.	2	designed the research|performed the experimental work	performed the experimental work	Performed the experiments	Investigation	YES
6270871	25079660	J.S.	2	designed the research|wrote the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
6270871	25079660	J.S.	2	designed the research|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6270871	25079660	R.L.Z.	2	performed the experimental work	performed the experimental work	Performed the experiments	Investigation	YES
5457577	28588895	AE	2	performed review of the manuscript	performed review of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5457577	28588895	BM	2	conceived of this idea for this manuscript and made final approval for submission	conceived of this idea for this manuscript and made final approval for submission	Conceived and designed the experiments	Conceptualization	YES
5457577	28588895	CJ	2	performed the literature review and wrote the initial draft	performed the literature review and wrote the initial draft	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5835723	29541084	FT	PLoS52	performed rna seq experiments|analyzed the data|wrote the manuscript	performed rna seq experiments	Performed the experiments	Investigation	YES
5835723	29541084	FT	PLoS52	performed rna seq experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5835723	29541084	FT	PLoS52	performed rna seq experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5835723	29541084	JH	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5835723	29541084	JW	PLoS52	performed rna seq experiments	performed rna seq experiments	Performed the experiments	Investigation	YES
5835723	29541084	JY	PLoS52	planned and designed the research	planned and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5835723	29541084	XC	PLoS52	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5835723	29541084	XH	PLoS52	planned and designed the research|wrote the manuscript	planned and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5835723	29541084	XH	PLoS52	planned and designed the research|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5835723	29541084	XX	PLoS52	planned and designed the research|wrote the manuscript	planned and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5835723	29541084	XX	PLoS52	planned and designed the research|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5835723	29541084	ZG	PLoS52	performed rna seq experiments	performed rna seq experiments	Performed the experiments	Investigation	YES
4418741	25938463	CAB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418741	25938463	CAB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418741	25938463	CAB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418741	25938463	CAB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418741	25938463	CRM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418741	25938463	CRM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418741	25938463	CRM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418741	25938463	CRM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418741	25938463	CRM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418741	25938463	CWW	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418741	25938463	CWW	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418741	25938463	CWW	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418741	25938463	MJP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418741	25938463	MJP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418741	25938463	MJP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418741	25938463	MJP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418741	25938463	MJP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418741	25938463	MRQ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418741	25938463	MRQ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418741	25938463	MRQ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418741	25938463	PJB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418741	25938463	PJB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418741	25938463	PJB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418741	25938463	PJB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418741	25938463	PJB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2020441	17957243	KD	PLoS5	Wrote the paper|Organized clinical investigation of our patients and controls|Discussed the results|Participated in the editing manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2020441	17957243	KD	PLoS5	Wrote the paper|Organized clinical investigation of our patients and controls|Discussed the results|Participated in the editing manuscript	Organized clinical investigation of our patients and controls	Performed the experiments	Investigation	YES
2020441	17957243	KD	PLoS5	Wrote the paper|Organized clinical investigation of our patients and controls|Discussed the results|Participated in the editing manuscript	Discussed the results	-	-	NO
2020441	17957243	KD	PLoS5	Wrote the paper|Organized clinical investigation of our patients and controls|Discussed the results|Participated in the editing manuscript	Participated in the editing manuscript	Wrote the paper	Writing - Review & Editing	YES
2020441	17957243	MC	PLoS5	Organized clinical investigation of our patients and controls|Discussed the results|Participated in the editing manuscript	Organized clinical investigation of our patients and controls	Performed the experiments	Investigation	YES
2020441	17957243	MC	PLoS5	Organized clinical investigation of our patients and controls|Discussed the results|Participated in the editing manuscript	Discussed the results	-	-	NO
2020441	17957243	MC	PLoS5	Organized clinical investigation of our patients and controls|Discussed the results|Participated in the editing manuscript	Participated in the editing manuscript	Wrote the paper	Writing - Review & Editing	YES
2020441	17957243	MH	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
2020441	17957243	MH	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2020441	17957243	MJ	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2020441	17957243	MJ	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2020441	17957243	MJ	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2020441	17957243	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2020441	17957243	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2020441	17957243	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2020441	17957243	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2020441	17957243	OD	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2020441	17957243	OD	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2020441	17957243	OD	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2020441	17957243	PD	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
2020441	17957243	PD	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2020441	17957243	RM	PLoS5	Conceived and designed the experiments|Organized clinical investigation of our patients and controls|Discussed the results	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2020441	17957243	RM	PLoS5	Conceived and designed the experiments|Organized clinical investigation of our patients and controls|Discussed the results	Organized clinical investigation of our patients and controls	Performed the experiments	Investigation	YES
2020441	17957243	RM	PLoS5	Conceived and designed the experiments|Organized clinical investigation of our patients and controls|Discussed the results	Discussed the results	-	-	NO
2020441	17957243	SL	PLoS5	Performed the experiments|Discussed the results|Participated in the editing manuscript	Performed the experiments	Performed the experiments	Investigation	YES
2020441	17957243	SL	PLoS5	Performed the experiments|Discussed the results|Participated in the editing manuscript	Discussed the results	-	-	NO
2020441	17957243	SL	PLoS5	Performed the experiments|Discussed the results|Participated in the editing manuscript	Participated in the editing manuscript	Wrote the paper	Writing - Review & Editing	YES
3721474	23776131	AM	PLoS52	performed the in vitro ubiquitylation assays	performed the in vitro ubiquitylation assays	Performed the experiments	Investigation	YES
3721474	23776131	ASR	PLoS52	performed experiments in rat1 cells and hct fbxw7 ko cells	performed experiments in rat1 cells and hct fbxw7 ko cells	Performed the experiments	Investigation	YES
3721474	23776131	CAKS	PLoS52	generated the fbxo28 specific antibody	generated the fbxo28 specific antibody	Performed the experiments	Investigation	YES
3721474	23776131	CS	PLoS52	performed protein expression analyses of cohort 1 breast cancer specimens	performed protein expression analyses of cohort 1 breast cancer specimens	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3721474	23776131	DC	PLoS52	performed the majority of the experiments|wrote the paper	performed the majority of the experiments	Performed the experiments	Investigation	YES
3721474	23776131	DC	PLoS52	performed the majority of the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3721474	23776131	DG	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3721474	23776131	DK	PLoS52	performed the microarray	performed the microarray	Performed the experiments	Investigation	YES
3721474	23776131	DS	PLoS52	performed protein expression analyses of cohort 1 breast cancer specimens	performed protein expression analyses of cohort 1 breast cancer specimens	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3721474	23776131	EF	PLoS52	performed data analyses	performed data analyses	Analyzed the data	Formal analysis	YES
3721474	23776131	FV	PLoS52	performed the mouse assays	performed the mouse assays	Performed the experiments	Investigation	YES
3721474	23776131	HFN	PLoS52	performed the majority of the experiments	performed the majority of the experiments	Performed the experiments	Investigation	YES
3721474	23776131	HN	PLoS52	performed the luciferase assays	performed the luciferase assays	Performed the experiments	Investigation	YES
3721474	23776131	HRS	PLoS52	performed the majority of the experiments	performed the majority of the experiments	Performed the experiments	Investigation	YES
3721474	23776131	JR	PLoS52	performed and analysed the csma studies	performed and analysed the csma studies	Performed the experiments	Investigation	YES
3721474	23776131	LGL	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3721474	23776131	ML	PLoS52	performed mass spectometry experiments	performed mass spectometry experiments	Performed the experiments	Investigation	YES
3721474	23776131	MLN	PLoS52	performed mass spectometry experiments	performed mass spectometry experiments	Performed the experiments	Investigation	YES
3721474	23776131	MU	PLoS52	generated the fbxo28 specific antibody	generated the fbxo28 specific antibody	Performed the experiments	Investigation	YES
3721474	23776131	MW	PLoS52	performed protein expression analyses of cohort 1 breast cancer specimens	performed protein expression analyses of cohort 1 breast cancer specimens	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3721474	23776131	NB	PLoS52	performed experiments in rat1 cells and hct fbxw7 ko cells|performed data analyses	performed experiments in rat1 cells and hct fbxw7 ko cells	Performed the experiments	Investigation	YES
3721474	23776131	NB	PLoS52	performed experiments in rat1 cells and hct fbxw7 ko cells|performed data analyses	performed data analyses	Analyzed the data	Formal analysis	YES
3721474	23776131	OS	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3721474	23776131	SG	PLoS52	performed data analyses	performed data analyses	Analyzed the data	Formal analysis	YES
3721474	23776131	SM	PLoS52	performed the majority of the experiments	performed the majority of the experiments	Performed the experiments	Investigation	YES
3721474	23776131	TMA	PLoS52	statistical analyses	statistical analyses	Analyzed the data	Formal analysis	YES
3721474	23776131	VSC	PLoS52	performed the mouse assays	performed the mouse assays	Performed the experiments	Investigation	YES
5597742	28893942	All authors	2	contributed to writing the manuscript and gave final approval for publication	contributed to writing the manuscript and gave final approval for publication	Wrote the paper	Writing - Original Draft	YES
4378212	25820558	AC	2	experiments concept and design|manuscript writing	experiments concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4378212	25820558	AC	2	experiments concept and design|manuscript writing	manuscript writing	Wrote the paper	Writing - Original Draft	YES
4378212	25820558	AN	2	surgical interventions performing, bone samples withdrawing	surgical interventions performing, bone samples withdrawing	Performed the experiments	Investigation	YES
4378212	25820558	CDN	2	experiments performing, data analysis|manuscript writing	experiments performing, data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4378212	25820558	CDN	2	experiments performing, data analysis|manuscript writing	manuscript writing	Wrote the paper	Writing - Original Draft	YES
4378212	25820558	GTete	2	experiments performing, data analysis	experiments performing, data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4378212	25820558	GTeti	2	experiments performing, data analysis	experiments performing, data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4378212	25820558	MF	2	experiments performing, data analysis	experiments performing, data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4378212	25820558	SZ	2	experiments performing, data analysis	experiments performing, data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4378212	25820558	VLZ	2	experiments performing, data analysis|manuscript writing	experiments performing, data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4378212	25820558	VLZ	2	experiments performing, data analysis|manuscript writing	manuscript writing	Wrote the paper	Writing - Original Draft	YES
4378212	25820558	VZ	2	surgical interventions performing, bone samples withdrawing	surgical interventions performing, bone samples withdrawing	Performed the experiments	Investigation	YES
5822475	29466941	AGM	2	conceptualized the study and experiments|contributed to funding acquisition and review and editing	conceptualized the study and experiments	Conceived and designed the experiments	Conceptualization	YES
5822475	29466941	AGM	2	conceptualized the study and experiments|contributed to funding acquisition and review and editing	contributed to funding acquisition and review and editing	Wrote the paper	Funding acquisition|Writing - Review & Editing	YES
5822475	29466941	BDS	2	contributed to funding acquisition and review and editing	contributed to funding acquisition and review and editing	Wrote the paper	Funding acquisition|Writing - Review & Editing	YES
5822475	29466941	DJM	2	contributed to funding acquisition and review and editing	contributed to funding acquisition and review and editing	Wrote the paper	Funding acquisition|Writing - Review & Editing	YES
5822475	29466941	KA	2	contributed to funding acquisition and review and editing	contributed to funding acquisition and review and editing	Wrote the paper	Funding acquisition|Writing - Review & Editing	YES
5822475	29466941	MPM	2	conceptualized the study and experiments|designed methodology and performed formal analysis, validation, data curation, software design, and writing of the first draft	conceptualized the study and experiments	Conceived and designed the experiments	Conceptualization	YES
5822475	29466941	MPM	2	conceptualized the study and experiments|designed methodology and performed formal analysis, validation, data curation, software design, and writing of the first draft	designed methodology and performed formal analysis, validation, data curation, software design, and writing of the first draft	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Data curation|Formal analysis|Investigation|Methodology|Software|Validation|Writing - Original Draft	YES
5822475	29466941	RJD	2	contributed to funding acquisition and review and editing	contributed to funding acquisition and review and editing	Wrote the paper	Funding acquisition|Writing - Review & Editing	YES
6029982	29971620	All authors	2	have contributed to this research work|read and approved the final manuscript	have contributed to this research work	Performed the experiments	Investigation	YES
6029982	29971620	All authors	2	have contributed to this research work|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5461727	28603624	HU	2	searched the literature, selected the papers, extracted the data, interpretended the data, drafted the manuscript, and approved the final version to be published	searched the literature, selected the papers, extracted the data, interpretended the data, drafted the manuscript, and approved the final version to be published	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5461727	28603624	SK	2	revised the draft and approved the final manuscript	revised the draft and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
2020442	17957244	MC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Recruited and assessed the participants|Wrote the first manuscript draft|Performed matlab programming|Responsible for the experimental design	Performed the experiments	Performed the experiments	Investigation	YES
2020442	17957244	MC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Recruited and assessed the participants|Wrote the first manuscript draft|Performed matlab programming|Responsible for the experimental design	Analyzed the data	Analyzed the data	Formal analysis	YES
2020442	17957244	MC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Recruited and assessed the participants|Wrote the first manuscript draft|Performed matlab programming|Responsible for the experimental design	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2020442	17957244	MC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Recruited and assessed the participants|Wrote the first manuscript draft|Performed matlab programming|Responsible for the experimental design	Recruited and assessed the participants	Performed the experiments	Investigation	YES
2020442	17957244	MC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Recruited and assessed the participants|Wrote the first manuscript draft|Performed matlab programming|Responsible for the experimental design	Wrote the first manuscript draft	Wrote the paper	Writing - Original Draft	YES
2020442	17957244	MC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Recruited and assessed the participants|Wrote the first manuscript draft|Performed matlab programming|Responsible for the experimental design	Performed matlab programming	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
2020442	17957244	MC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper|Recruited and assessed the participants|Wrote the first manuscript draft|Performed matlab programming|Responsible for the experimental design	Responsible for the experimental design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
2020442	17957244	PB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Provided support for matlab programming|Revised the manuscript|Responsible for the experimental design	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2020442	17957244	PB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Provided support for matlab programming|Revised the manuscript|Responsible for the experimental design	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2020442	17957244	PB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Provided support for matlab programming|Revised the manuscript|Responsible for the experimental design	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2020442	17957244	PB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Provided support for matlab programming|Revised the manuscript|Responsible for the experimental design	Provided support for matlab programming	Contributed reagents/materials/analysis tools	Software	YES
2020442	17957244	PB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Provided support for matlab programming|Revised the manuscript|Responsible for the experimental design	Revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
2020442	17957244	PB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Provided support for matlab programming|Revised the manuscript|Responsible for the experimental design	Responsible for the experimental design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
2020442	17957244	SD	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Provided support for matlab programming|Revised the manuscript|Responsible for the experimental design	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2020442	17957244	SD	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Provided support for matlab programming|Revised the manuscript|Responsible for the experimental design	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2020442	17957244	SD	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Provided support for matlab programming|Revised the manuscript|Responsible for the experimental design	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2020442	17957244	SD	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Provided support for matlab programming|Revised the manuscript|Responsible for the experimental design	Provided support for matlab programming	Contributed reagents/materials/analysis tools	Software	YES
2020442	17957244	SD	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Provided support for matlab programming|Revised the manuscript|Responsible for the experimental design	Revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
2020442	17957244	SD	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Provided support for matlab programming|Revised the manuscript|Responsible for the experimental design	Responsible for the experimental design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6270872	24950437	A.M.L.S.	2	performed the synthesis and the reducing power and radical scavenging activity assays|analyzed the data and wrote the paper	performed the synthesis and the reducing power and radical scavenging activity assays	Performed the experiments	Investigation	YES
6270872	24950437	A.M.L.S.	2	performed the synthesis and the reducing power and radical scavenging activity assays|analyzed the data and wrote the paper	analyzed the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6270872	24950437	A.M.S.S.	2	designed research|analyzed the data and wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
6270872	24950437	A.M.S.S.	2	designed research|analyzed the data and wrote the paper	analyzed the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6270872	24950437	D.C.G.A.P.	2	designed research|performed the synthesis and the reducing power and radical scavenging activity assays|analyzed the data and wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
6270872	24950437	D.C.G.A.P.	2	designed research|performed the synthesis and the reducing power and radical scavenging activity assays|analyzed the data and wrote the paper	performed the synthesis and the reducing power and radical scavenging activity assays	Performed the experiments	Investigation	YES
6270872	24950437	D.C.G.A.P.	2	designed research|performed the synthesis and the reducing power and radical scavenging activity assays|analyzed the data and wrote the paper	analyzed the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6270872	24950437	M.C.B.	2	performed the anti-ache assay	performed the anti-ache assay	Performed the experiments	Investigation	YES
6270872	24950437	S.B.L.	2	performed the synthesis and the reducing power and radical scavenging activity assays	performed the synthesis and the reducing power and radical scavenging activity assays	Performed the experiments	Investigation	YES
5835757	29541085	CZ	2	initiated and designed the experiments|performed the experiments, analyzed the data, and wrote the manuscript	initiated and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5835757	29541085	CZ	2	initiated and designed the experiments|performed the experiments, analyzed the data, and wrote the manuscript	performed the experiments, analyzed the data, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5835757	29541085	SS	2	initiated and designed the experiments|guided the research	initiated and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5835757	29541085	SS	2	initiated and designed the experiments|guided the research	guided the research	-	Supervision	YES
4418742	25938582	DN	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418742	25938582	DN	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418742	25938582	DN	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418742	25938582	FM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418742	25938582	FM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418742	25938582	FM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418742	25938582	LJM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418742	25938582	LJM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418742	25938582	LJM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418742	25938582	LJM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418742	25938582	TGO	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418742	25938582	TGO	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3721475	23681745	AEN	PLoS52	performed the experiments|performed the experiments|analyzed the data|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
3721475	23681745	AEN	PLoS52	performed the experiments|performed the experiments|analyzed the data|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
3721475	23681745	AEN	PLoS52	performed the experiments|performed the experiments|analyzed the data|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
3721475	23681745	AEN	PLoS52	performed the experiments|performed the experiments|analyzed the data|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
3721475	23681745	AMF	PLoS52	analyzed the data|contributed new reagents/analytic tools	analyzed the data	Analyzed the data	Formal analysis	YES
3721475	23681745	AMF	PLoS52	analyzed the data|contributed new reagents/analytic tools	contributed new reagents/analytic tools	Contributed reagents/materials/analysis tools	Resources	YES
3721475	23681745	AMN	PLoS52	designed the research|performed the experiments|analyzed the data|wrote the paper	designed the research	Conceived and designed the experiments	Methodology	YES
3721475	23681745	AMN	PLoS52	designed the research|performed the experiments|analyzed the data|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
3721475	23681745	AMN	PLoS52	designed the research|performed the experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
3721475	23681745	AMN	PLoS52	designed the research|performed the experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3721475	23681745	AN	PLoS52	contributed new reagents/analytic tools	contributed new reagents/analytic tools	Contributed reagents/materials/analysis tools	Resources	YES
3721475	23681745	DHW	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
3721475	23681745	DHW	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
3721475	23681745	FAS	PLoS52	contributed new reagents/analytic tools	contributed new reagents/analytic tools	Contributed reagents/materials/analysis tools	Resources	YES
3721475	23681745	FRRA	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
3721475	23681745	FRRA	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
3721475	23681745	HC	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
3721475	23681745	IWC	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
3721475	23681745	JHTGF	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
3721475	23681745	NL	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
3721475	23681745	PHS	PLoS52	designed the research|analyzed the data|wrote the paper	designed the research	Conceived and designed the experiments	Methodology	YES
3721475	23681745	PHS	PLoS52	designed the research|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
3721475	23681745	PHS	PLoS52	designed the research|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3721475	23681745	PM	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
3721475	23681745	PR	PLoS52	contributed new reagents/analytic tools	contributed new reagents/analytic tools	Contributed reagents/materials/analysis tools	Resources	YES
3721475	23681745	PRV	PLoS52	contributed new reagents/analytic tools	contributed new reagents/analytic tools	Contributed reagents/materials/analysis tools	Resources	YES
3721475	23681745	RJA	PLoS52	contributed new reagents/analytic tools	contributed new reagents/analytic tools	Contributed reagents/materials/analysis tools	Resources	YES
3721475	23681745	SJS	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
3721475	23681745	TJT	PLoS52	contributed new reagents/analytic tools	contributed new reagents/analytic tools	Contributed reagents/materials/analysis tools	Resources	YES
3721475	23681745	YZW	PLoS52	contributed new reagents/analytic tools	contributed new reagents/analytic tools	Contributed reagents/materials/analysis tools	Resources	YES
4378213	25820559	FZ	2	experiments performing, data analysis, manuscript drafting	experiments performing, data analysis, manuscript drafting	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4378213	25820559	HZ	2	samples collection assistance, experiments performing, manuscript revision	samples collection assistance, experiments performing, manuscript revision	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4378213	25820559	QL	2	experiments performing, data analysis, manuscript drafting	experiments performing, data analysis, manuscript drafting	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4378213	25820559	QW	2	study design and supervision, manuscript revision	study design and supervision, manuscript revision	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Review & Editing	YES
4378213	25820559	SZ	2	experiments performing, data analysis, manuscript drafting	experiments performing, data analysis, manuscript drafting	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4378213	25820559	XS	2	samples collection assistance, experiments performing, manuscript revision	samples collection assistance, experiments performing, manuscript revision	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4378213	25820559	YH	2	study design and supervision, manuscript revision	study design and supervision, manuscript revision	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Review & Editing	YES
4378213	25820559	ZY	2	study design and supervision, manuscript revision	study design and supervision, manuscript revision	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Review & Editing	YES
5822529	29466940	AH	7	analysis and acquisition of data, KK, JK, VK, and MM Jr.: design of the study, interpretation of data and revising the manuscript	analysis and acquisition of data, KK, JK, VK, and MM Jr.: design of the study, interpretation of data and revising the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Review & Editing	YES
5822529	29466940	ED	7	analysis and acquisition of data, KK, JK, VK, and MM Jr.: design of the study, interpretation of data and revising the manuscript	analysis and acquisition of data, KK, JK, VK, and MM Jr.: design of the study, interpretation of data and revising the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Review & Editing	YES
5822529	29466940	GI	7	design of the study, analysis, acquisition and interpretation of data, writing the manuscript	design of the study, analysis, acquisition and interpretation of data, writing the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5822529	29466940	IB	7	design of the study, interpretation of data and writing the manuscript	design of the study, interpretation of data and writing the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5822529	29466940	LM	7	analysis and acquisition of data, KK, JK, VK, and MM Jr.: design of the study, interpretation of data and revising the manuscript	analysis and acquisition of data, KK, JK, VK, and MM Jr.: design of the study, interpretation of data and revising the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Review & Editing	YES
2020443	17957245	AB	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2020443	17957245	CC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2020443	17957245	CC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2020443	17957245	CC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2020443	17957245	CS	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2020443	17957245	CS	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2020443	17957245	DO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2020443	17957245	DO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2020443	17957245	DO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2020443	17957245	DO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2020443	17957245	EW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
2020443	17957245	JL	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2020443	17957245	JL	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2020443	17957245	MW	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2020443	17957245	MW	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2020443	17957245	NB	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2020443	17957245	NT	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2020443	17957245	NT	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2020443	17957245	RY	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2020443	17957245	RY	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2020443	17957245	ST	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4378214	25820560	ADV	2	study design and paper writing	study design and paper writing	Conceived and designed the experiments|Wrote the paper	Methodology	YES
4378214	25820560	All authors	2	revised and approved the final draft of the manuscript	revised and approved the final draft of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4378214	25820560	CC	2	histology and immunohistochemistry	histology and immunohistochemistry	Performed the experiments	Investigation	YES
4378214	25820560	CM	2	histological evaluation	histological evaluation	Performed the experiments	Investigation	YES
4378214	25820560	CP	2	participation in manuscript revision and immunofluorescence	participation in manuscript revision and immunofluorescence	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4378214	25820560	ES	2	cases critical selection	cases critical selection	-	-	NO
4378214	25820560	GD	2	study design and paper writing|contribute equally to the paper	study design and paper writing	Conceived and designed the experiments|Wrote the paper	Methodology	YES
4378214	25820560	GD	2	study design and paper writing|contribute equally to the paper	contribute equally to the paper	-	-	NO
4378214	25820560	GF	2	histology and immunohistochemistry	histology and immunohistochemistry	Performed the experiments	Investigation	YES
4378214	25820560	IP	2	cell culture and western blotting	cell culture and western blotting	Performed the experiments	Investigation	YES
4378214	25820560	TB	2	study design and paper writing|contribute equally to the paper	study design and paper writing	Conceived and designed the experiments|Wrote the paper	Methodology	YES
4378214	25820560	TB	2	study design and paper writing|contribute equally to the paper	contribute equally to the paper	-	-	NO
6029988	29971574	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6029988	29971574	JS	2	analysed and interpreted the data	analysed and interpreted the data	Analyzed the data	Formal analysis	YES
6029988	29971574	MN	2	performed the experiment, collected the data	performed the experiment, collected the data	Performed the experiments	Investigation	YES
6029988	29971574	SQL	2	analysed, interpreted the data, and wrote and revised the manuscript	analysed, interpreted the data, and wrote and revised the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
6029988	29971574	YL	2	analysed and interpreted the data, wrote the manuscript	analysed and interpreted the data, wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5835797	29541088	KI	2	revised and finalized the paper	revised and finalized the paper	Wrote the paper	Writing - Review & Editing	YES
5835797	29541088	KO	2	contributed analytic tools	contributed analytic tools	Contributed reagents/materials/analysis tools	Resources	YES
5835797	29541088	MB	2	interpreted the data|contributed to the conception and design of the work|wrote the manuscript|revised and finalized the paper	interpreted the data	Analyzed the data	Formal analysis	YES
5835797	29541088	MB	2	interpreted the data|contributed to the conception and design of the work|wrote the manuscript|revised and finalized the paper	contributed to the conception and design of the work	Conceived and designed the experiments	Conceptualization	YES
5835797	29541088	MB	2	interpreted the data|contributed to the conception and design of the work|wrote the manuscript|revised and finalized the paper	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5835797	29541088	MB	2	interpreted the data|contributed to the conception and design of the work|wrote the manuscript|revised and finalized the paper	revised and finalized the paper	Wrote the paper	Writing - Review & Editing	YES
5835797	29541088	TI	2	contributed analytic tools	contributed analytic tools	Contributed reagents/materials/analysis tools	Resources	YES
5835797	29541088	TK	2	designed and supervised the research	designed and supervised the research	Conceived and designed the experiments	Methodology|Supervision	YES
5835797	29541088	TM	2	designed and supervised the research|interpreted the data|wrote the manuscript|revised and finalized the paper	designed and supervised the research	Conceived and designed the experiments	Methodology|Supervision	YES
5835797	29541088	TM	2	designed and supervised the research|interpreted the data|wrote the manuscript|revised and finalized the paper	interpreted the data	Analyzed the data	Formal analysis	YES
5835797	29541088	TM	2	designed and supervised the research|interpreted the data|wrote the manuscript|revised and finalized the paper	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5835797	29541088	TM	2	designed and supervised the research|interpreted the data|wrote the manuscript|revised and finalized the paper	revised and finalized the paper	Wrote the paper	Writing - Review & Editing	YES
5835797	29541088	TO	2	contributed analytic tools	contributed analytic tools	Contributed reagents/materials/analysis tools	Resources	YES
5835797	29541088	TT	2	performed the experiments and carried out the analysis|interpreted the data|wrote the manuscript	performed the experiments and carried out the analysis	Performed the experiments	Investigation	YES
5835797	29541088	TT	2	performed the experiments and carried out the analysis|interpreted the data|wrote the manuscript	interpreted the data	Analyzed the data	Formal analysis	YES
5835797	29541088	TT	2	performed the experiments and carried out the analysis|interpreted the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5461773	28603625	HM	2	participated in the design of the study|revised and edited the manuscript	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
5461773	28603625	HM	2	participated in the design of the study|revised and edited the manuscript	revised and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5461773	28603625	Kazuyoshi Shimizu	2	participated in the design of the study|revised and edited the manuscript	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
5461773	28603625	Kazuyoshi Shimizu	2	participated in the design of the study|revised and edited the manuscript	revised and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5461773	28603625	Kentaro Sugimoto	2	participated in the design of the study|revised and edited the manuscript	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
5461773	28603625	Kentaro Sugimoto	2	participated in the design of the study|revised and edited the manuscript	revised and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5461773	28603625	NS	2	collected data and performed statistical analysis|wrote the manuscript	collected data and performed statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5461773	28603625	NS	2	collected data and performed statistical analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5461773	28603625	TI	2	participated in the design of the study|revised and edited the manuscript	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
5461773	28603625	TI	2	participated in the design of the study|revised and edited the manuscript	revised and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5461773	28603625	TK	2	participated in the design of the study|revised and edited the manuscript	participated in the design of the study	Conceived and designed the experiments	Methodology	YES
5461773	28603625	TK	2	participated in the design of the study|revised and edited the manuscript	revised and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5461773	28603625	TS	2	revised and edited the manuscript	revised and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5461773	28603625	YK	2	revised and edited the manuscript	revised and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
6270874	25215586	A.E.D.A.	2	designed the experiments and executed the chemical synthesis	designed the experiments and executed the chemical synthesis	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6270874	25215586	All authors	2	wrote the paper, discussed the results and commented on the manuscript	wrote the paper, discussed the results and commented on the manuscript	Wrote the paper	Writing - Original Draft	YES
6270874	25215586	L.M.S.	2	designed the experiments and executed the chemical synthesis	designed the experiments and executed the chemical synthesis	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6270874	25215586	P.D.	2	conceived the project	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5627161	28947658	B.E.	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5627161	28947658	B.d.H.	PLoS52	designed the experiments|performed the experiments|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5627161	28947658	B.d.H.	PLoS52	designed the experiments|performed the experiments|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5627161	28947658	B.d.H.	PLoS52	designed the experiments|performed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5627161	28947658	E.R.	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5627161	28947658	E.S.	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5627161	28947658	J.C.W.D.	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5627161	28947658	J.E.M.M.d.K.	PLoS52	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5627161	28947658	J.G.	PLoS52	designed the experiments|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5627161	28947658	J.G.	PLoS52	designed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5627161	28947658	J.L.	PLoS52	collected patient material and conducted the initial screen	collected patient material and conducted the initial screen	Performed the experiments	Investigation	YES
5627161	28947658	J.S.E.L.	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5627161	28947658	M.v.d.H.	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
4418743	25938589	DG	PLoS5	Wrote the paper|Final approval of the manuscript submitted	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418743	25938589	DG	PLoS5	Wrote the paper|Final approval of the manuscript submitted	Final approval of the manuscript submitted	-	-	NO
4418743	25938589	HG	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Final approval of the manuscript submitted	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418743	25938589	HG	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Final approval of the manuscript submitted	Performed the experiments	Performed the experiments	Investigation	YES
4418743	25938589	HG	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Final approval of the manuscript submitted	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418743	25938589	HG	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Final approval of the manuscript submitted	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418743	25938589	HG	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Final approval of the manuscript submitted	Final approval of the manuscript submitted	-	-	NO
4418743	25938589	JD	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Final approval of the manuscript submitted	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418743	25938589	JD	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Final approval of the manuscript submitted	Performed the experiments	Performed the experiments	Investigation	YES
4418743	25938589	JD	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Final approval of the manuscript submitted	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418743	25938589	JD	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Final approval of the manuscript submitted	Final approval of the manuscript submitted	-	-	NO
4418743	25938589	LPL	PLoS5	Wrote the paper|Final approval of the manuscript submitted	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418743	25938589	LPL	PLoS5	Wrote the paper|Final approval of the manuscript submitted	Final approval of the manuscript submitted	-	-	NO
4418743	25938589	LXS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4418743	25938589	LXS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4418743	25938589	LXS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418743	25938589	MZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Final approval of the manuscript submitted	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418743	25938589	MZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Final approval of the manuscript submitted	Performed the experiments	Performed the experiments	Investigation	YES
4418743	25938589	MZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Final approval of the manuscript submitted	Analyzed the data	Analyzed the data	Formal analysis	YES
4418743	25938589	MZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Final approval of the manuscript submitted	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418743	25938589	MZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Final approval of the manuscript submitted	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418743	25938589	MZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Final approval of the manuscript submitted	Final approval of the manuscript submitted	-	-	NO
4418743	25938589	RRG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Final approval of the manuscript submitted	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418743	25938589	RRG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Final approval of the manuscript submitted	Analyzed the data	Analyzed the data	Formal analysis	YES
4418743	25938589	RRG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Final approval of the manuscript submitted	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418743	25938589	RRG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Final approval of the manuscript submitted	Final approval of the manuscript submitted	-	-	NO
4418743	25938589	SPN	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418743	25938589	YM	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418743	25938589	YM	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3721476	23740718	GDC	2	were responsible for chemical design and synthesis	were responsible for chemical design and synthesis	Conceived and designed the experiments	-	YES
3721476	23740718	SC	2	were responsible for chemical design and synthesis	were responsible for chemical design and synthesis	Conceived and designed the experiments	-	YES
3721476	23740718	XX	2	were responsible for chemical design and synthesis	were responsible for chemical design and synthesis	Conceived and designed the experiments	-	YES
5822635	29466945	DV	2	directed the project, contributed to the analysis and manuscript revisions	directed the project, contributed to the analysis and manuscript revisions	Wrote the paper	Supervision|Writing - Review & Editing	YES
5822635	29466945	NCK	2	directed the project, contributed to the analysis and manuscript revisions	directed the project, contributed to the analysis and manuscript revisions	Wrote the paper	Supervision|Writing - Review & Editing	YES
5822635	29466945	RP	2	analyzed the data and wrote the first draft of the manuscript	analyzed the data and wrote the first draft of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4378215	25820561	DC	2	esem-eds analyses, manuscript writing	esem-eds analyses, manuscript writing	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4378215	25820561	EF	2	contributed equally to this work|data interpretation and coordination	contributed equally to this work	-	-	NO
4378215	25820561	EF	2	contributed equally to this work|data interpretation and coordination	data interpretation and coordination	Analyzed the data	Formal analysis|Project administration	YES
4378215	25820561	FF	2	foraminiferal analysis and manuscript writing	foraminiferal analysis and manuscript writing	Wrote the paper	Writing - Original Draft	YES
4378215	25820561	FMG	2	laboratory treatment	laboratory treatment	-	-	NO
4378215	25820561	JMB	2	data interpretation	data interpretation	Analyzed the data	Formal analysis	YES
4378215	25820561	RC	2	contributed equally to this work|project coordinator	contributed equally to this work	-	-	NO
4378215	25820561	RC	2	contributed equally to this work|project coordinator	project coordinator	-	Project administration	YES
4378215	25820561	TEM	2	esem-eds analyses, manuscript writing	esem-eds analyses, manuscript writing	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
2031823	17957253	BC	PLoS5	Critically reviewed the manuscript for intellectual content|Advised on data analysis	Critically reviewed the manuscript for intellectual content	Wrote the paper	Writing - Review & Editing	YES
2031823	17957253	BC	PLoS5	Critically reviewed the manuscript for intellectual content|Advised on data analysis	Advised on data analysis	Analyzed the data	Formal analysis	YES
2031823	17957253	CS	PLoS5	Analyzed the data|Wrote the paper|Conceived and designed the hypothesis tested here	Analyzed the data	Analyzed the data	Formal analysis	YES
2031823	17957253	CS	PLoS5	Analyzed the data|Wrote the paper|Conceived and designed the hypothesis tested here	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2031823	17957253	CS	PLoS5	Analyzed the data|Wrote the paper|Conceived and designed the hypothesis tested here	Conceived and designed the hypothesis tested here	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
2031823	17957253	EJ	PLoS5	Critically reviewed the manuscript for intellectual content|Conceived and designed the original study	Critically reviewed the manuscript for intellectual content	Wrote the paper	Writing - Review & Editing	YES
2031823	17957253	EJ	PLoS5	Critically reviewed the manuscript for intellectual content|Conceived and designed the original study	Conceived and designed the original study	Conceived and designed the experiments	Conceptualization|Methodology	YES
2031823	17957253	GL	PLoS5	Contributed to the hypothesis, design and writing of the paper|Critically reviewed the manuscript for intellectual content	Contributed to the hypothesis, design and writing of the paper	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
2031823	17957253	GL	PLoS5	Contributed to the hypothesis, design and writing of the paper|Critically reviewed the manuscript for intellectual content	Critically reviewed the manuscript for intellectual content	Wrote the paper	Writing - Review & Editing	YES
2031823	17957253	GT	PLoS5	Critically reviewed the manuscript for intellectual content	Critically reviewed the manuscript for intellectual content	Wrote the paper	Writing - Review & Editing	YES
2031823	17957253	MH	PLoS5	Critically reviewed the manuscript for intellectual content|Advised on the hypothesis	Critically reviewed the manuscript for intellectual content	Wrote the paper	Writing - Review & Editing	YES
2031823	17957253	MH	PLoS5	Critically reviewed the manuscript for intellectual content|Advised on the hypothesis	Advised on the hypothesis	-	-	NO
2031823	17957253	TL	PLoS5	Critically reviewed the manuscript for intellectual content|Conceived and designed the original study	Critically reviewed the manuscript for intellectual content	Wrote the paper	Writing - Review & Editing	YES
2031823	17957253	TL	PLoS5	Critically reviewed the manuscript for intellectual content|Conceived and designed the original study	Conceived and designed the original study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5835929	29541083	MD	PLoS52	carried out the transgenic study, gene expression, cell-level and other functional analyses|wrote the paper	carried out the transgenic study, gene expression, cell-level and other functional analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5835929	29541083	MD	PLoS52	carried out the transgenic study, gene expression, cell-level and other functional analyses|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5835929	29541083	SY	PLoS52	designed the research|wrote the paper	designed the research	Conceived and designed the experiments	Methodology	YES
5835929	29541083	SY	PLoS52	designed the research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5835929	29541083	XF	PLoS52	designed the research|wrote the paper	designed the research	Conceived and designed the experiments	Methodology	YES
5835929	29541083	XF	PLoS52	designed the research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5835929	29541083	YZ	PLoS52	cloned the oszou genes and performed the phylogenetic analysis and mutant complementation|wrote the paper	cloned the oszou genes and performed the phylogenetic analysis and mutant complementation	Performed the experiments	Investigation	YES
5835929	29541083	YZ	PLoS52	cloned the oszou genes and performed the phylogenetic analysis and mutant complementation|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6033843	29978349	All	2	data supporting the results and discussion, and conclusions of this study are included in the manuscript	data supporting the results and discussion, and conclusions of this study are included in the manuscript	-	-	NO
6033843	29978349	All authors	2	read and approved the final manuscript|gave their consent for publication	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6033843	29978349	All authors	2	read and approved the final manuscript|gave their consent for publication	gave their consent for publication	-	-	NO
6033843	29978349	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
6033843	29978349	XS	2	designed research, performed research, analyzed data, and wrote the paper	designed research, performed research, analyzed data, and wrote the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
6033843	29978349	YZ	2	designed research, performed research, analyzed data, and wrote the paper	designed research, performed research, analyzed data, and wrote the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5465672	28616241	HDS	2	designed the paper, participated in drafting the manuscript, and approved the final version of the manuscript	designed the paper, participated in drafting the manuscript, and approved the final version of the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
5465672	28616241	PMH	2	designed the paper, participated in drafting the manuscript, and approved the final version of the manuscript	designed the paper, participated in drafting the manuscript, and approved the final version of the manuscript	Conceived and designed the experiments|Wrote the paper	Writing - Original Draft	YES
4418745	25938677	KE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418745	25938677	KE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4418745	25938677	KE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418745	25938677	MS	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418745	25938677	MS	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418745	25938677	NK	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4418745	25938677	NK	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418745	25938677	RB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Designed the software used in analysis	Analyzed the data	Analyzed the data	Formal analysis	YES
4418745	25938677	RB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Designed the software used in analysis	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418745	25938677	RB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Designed the software used in analysis	Designed the software used in analysis	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
4418745	25938677	S. Sarkijarvi	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418745	25938677	S. Sarkijarvi	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418745	25938677	S. Selim	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418745	25938677	S. Selim	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418745	25938677	S. Selim	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418745	25938677	SJ	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418745	25938677	SJ	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418745	25938677	TK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418745	25938677	TK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418745	25938677	TK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418745	25938677	TK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418745	25938677	TR	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4418745	25938677	TR	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5824455	29471787	DC	2	performed qrt-pcr analysis	performed qrt-pcr analysis	Performed the experiments	Investigation	YES
5824455	29471787	HC	2	designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
5824455	29471787	HS	2	calculated all the data	calculated all the data	Analyzed the data	Formal analysis	YES
5824455	29471787	LZ	2	performed qrt-pcr analysis	performed qrt-pcr analysis	Performed the experiments	Investigation	YES
5824455	29471787	MC	2	performed qrt-pcr analysis	performed qrt-pcr analysis	Performed the experiments	Investigation	YES
5824455	29471787	MG	2	calculated all the data	calculated all the data	Analyzed the data	Formal analysis	YES
5824455	29471787	MY	2	performed qrt-pcr analysis	performed qrt-pcr analysis	Performed the experiments	Investigation	YES
5824455	29471787	MZ	2	performed phylogenetic and expression analysis|wrote the manuscript	performed phylogenetic and expression analysis	Performed the experiments	Investigation	YES
5824455	29471787	MZ	2	performed phylogenetic and expression analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5824455	29471787	QH	2	performed qrt-pcr analysis	performed qrt-pcr analysis	Performed the experiments	Investigation	YES
5824455	29471787	YL	2	annotated the genes on chromosomes and conducted the evolution analysis	annotated the genes on chromosomes and conducted the evolution analysis	Performed the experiments	Investigation	YES
5824455	29471787	YQ	2	designed the research|wrote the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
5824455	29471787	YQ	2	designed the research|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5627162	28947659	Both authors	2	gave final approval for publication	gave final approval for publication	-	-	NO
5627162	28947659	J.B.L.	2	gave final approval for publication	gave final approval for publication	-	-	NO
4378216	25820562	All authors	2	participated in the design, interpretation of the studies and analysis of the data and review of the manuscript	participated in the design, interpretation of the studies and analysis of the data and review of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Review & Editing	YES
4378216	25820562	MVC	2	manuscript writing	manuscript writing	Wrote the paper	Writing - Original Draft	YES
4378216	25820562	VF	2	experiments performing|manuscript writing	experiments performing	Performed the experiments	Investigation	YES
4378216	25820562	VF	2	experiments performing|manuscript writing	manuscript writing	Wrote the paper	Writing - Original Draft	YES
3721477	23703938	AU	2	designed experiments, performed surgeries and carried out histological analyses and counts	designed experiments, performed surgeries and carried out histological analyses and counts	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
3721477	23703938	BIPR	2	carried out analyses for protein aggregation	carried out analyses for protein aggregation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3721477	23703938	BWR	2	assisted with surgeries and histological preparations	assisted with surgeries and histological preparations	Performed the experiments	Investigation	YES
3721477	23703938	DADM	2	designed experiments, analyzed data and wrote the paper with input from the other authors	designed experiments, analyzed data and wrote the paper with input from the other authors	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3721477	23703938	MH	2	set up and performed image analysis and quantification of neuritic pathology	set up and performed image analysis and quantification of neuritic pathology	Performed the experiments|Analyzed the data	Investigation|Methodology|Visualization	YES
3721477	23703938	REM	2	set up and performed image analysis and quantification of neuritic pathology	set up and performed image analysis and quantification of neuritic pathology	Performed the experiments|Analyzed the data	Investigation|Methodology|Visualization	YES
3721477	23703938	RR	2	set up and performed qrt pcr	set up and performed qrt pcr	Performed the experiments	Investigation|Methodology	YES
6270877	24662076	All authors	2	contributed to this study	contributed to this study	-	-	NO
6270877	24662076	C. Kang	2	designed the experiment and wrote the first and final draft of the manuscript	designed the experiment and wrote the first and final draft of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
6270877	24662076	H. Cho	2	were collected natural products	were collected natural products	Performed the experiments	Investigation	YES
6270877	24662076	W. Park	2	performed compound separation	performed compound separation	Performed the experiments	Investigation	YES
6270877	24662076	Y. Lee	2	performed antibacterial experiments	performed antibacterial experiments	Performed the experiments	Investigation	YES
5836058	29541087	All authors	2	participated in discussions and provided suggestions for manuscript improvement	participated in discussions and provided suggestions for manuscript improvement	-	-	NO
5836058	29541087	CG	2	performed the transcriptome sequencing, assembly, and analyses	performed the transcriptome sequencing, assembly, and analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5836058	29541087	HH	2	performed the transcriptome sequencing, assembly, and analyses	performed the transcriptome sequencing, assembly, and analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5836058	29541087	JL	2	performed the cellular activity test	performed the cellular activity test	Performed the experiments	Investigation	YES
5836058	29541087	MY	2	conceived the study and directed the project|performed the cellular activity test|wrote the paper with input from all authors	conceived the study and directed the project	Conceived and designed the experiments	Conceptualization|Supervision	YES
5836058	29541087	MY	2	conceived the study and directed the project|performed the cellular activity test|wrote the paper with input from all authors	performed the cellular activity test	Performed the experiments	Investigation	YES
5836058	29541087	MY	2	conceived the study and directed the project|performed the cellular activity test|wrote the paper with input from all authors	wrote the paper with input from all authors	Wrote the paper	Writing - Original Draft	YES
5836058	29541087	SZ	2	conceived the study and directed the project|wrote the paper with input from all authors	conceived the study and directed the project	Conceived and designed the experiments	Conceptualization|Supervision	YES
5836058	29541087	SZ	2	conceived the study and directed the project|wrote the paper with input from all authors	wrote the paper with input from all authors	Wrote the paper	Writing - Original Draft	YES
5836058	29541087	XH	2	participated in the sample collection and sensitivity testing	participated in the sample collection and sensitivity testing	Performed the experiments	Investigation	YES
5836058	29541087	XM	2	performed the transcriptome sequencing, assembly, and analyses	performed the transcriptome sequencing, assembly, and analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5836058	29541087	YC	2	performed the cellular activity test|wrote the paper with input from all authors	performed the cellular activity test	Performed the experiments	Investigation	YES
5836058	29541087	YC	2	performed the cellular activity test|wrote the paper with input from all authors	wrote the paper with input from all authors	Wrote the paper	Writing - Original Draft	YES
5836058	29541087	YL	2	participated in the sample collection and sensitivity testing	participated in the sample collection and sensitivity testing	Performed the experiments	Investigation	YES
5836058	29541087	YX	2	performed the transcriptome sequencing, assembly, and analyses	performed the transcriptome sequencing, assembly, and analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
2031824	17957258	AM	PLoS5	Provided expertise for the design and analysis of the experiments	Provided expertise for the design and analysis of the experiments	Conceived and designed the experiments	Methodology	YES
2031824	17957258	BB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2031824	17957258	BB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
2031824	17957258	BB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2031824	17957258	JP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2031824	17957258	JP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2031824	17957258	JP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2031824	17957258	JP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2031824	17957258	LQ	PLoS5	Conceived the project|Contributed to data analysis|Contributed to writing of the paper	Conceived the project	Conceived and designed the experiments	Conceptualization	YES
2031824	17957258	LQ	PLoS5	Conceived the project|Contributed to data analysis|Contributed to writing of the paper	Contributed to data analysis	Analyzed the data	Formal analysis	YES
2031824	17957258	LQ	PLoS5	Conceived the project|Contributed to data analysis|Contributed to writing of the paper	Contributed to writing of the paper	Wrote the paper	Writing - Original Draft	YES
5477298	28649384	All authors	2	critically revised the manuscript for important intellectual content, provided intellectual input for the study and manuscript, and have read and approved the final manuscript	critically revised the manuscript for important intellectual content, provided intellectual input for the study and manuscript, and have read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5477298	28649384	KS	2	contributed to study design and data acquisition	contributed to study design and data acquisition	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources	YES
5477298	28649384	MK	2	contributed to the study conception and design, data acquisition, analysis, and interpretation, statistical analysis, and drafting of the manuscript	contributed to the study conception and design, data acquisition, analysis, and interpretation, statistical analysis, and drafting of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
5477298	28649384	YH	2	contributed to study design and data acquisition	contributed to study design and data acquisition	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources	YES
6038301	29946801	All authors	2	participated in discussion of the work, revised the manuscript and agreed to the final content|read and approved the final manuscript	participated in discussion of the work, revised the manuscript and agreed to the final content	Wrote the paper	Writing - Review & Editing	YES
6038301	29946801	All authors	2	participated in discussion of the work, revised the manuscript and agreed to the final content|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6038301	29946801	FL	2	constructed the model and performed simulations|analyzed the results and prepared the first draft of the manuscript	constructed the model and performed simulations	Performed the experiments	Formal analysis|Investigation|Methodology	YES
6038301	29946801	FL	2	constructed the model and performed simulations|analyzed the results and prepared the first draft of the manuscript	analyzed the results and prepared the first draft of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6038301	29946801	HL	2	helped to do the simulation	helped to do the simulation	-	Formal analysis	YES
6038301	29946801	HM	2	designed the experiments|supervised the project	designed the experiments	Conceived and designed the experiments	Methodology	YES
6038301	29946801	HM	2	designed the experiments|supervised the project	supervised the project	-	Supervision	YES
6038301	29946801	PL	2	helped to do the simulation	helped to do the simulation	-	Formal analysis	YES
6038301	29946801	QY	2	constructed the model and performed simulations	constructed the model and performed simulations	Performed the experiments	Formal analysis|Investigation|Methodology	YES
6038301	29946801	TC	2	edited and reviewed the draft	edited and reviewed the draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6038301	29946801	WX	2	designed the experiments|analyzed the results and prepared the first draft of the manuscript|supervised the project	designed the experiments	Conceived and designed the experiments	Methodology	YES
6038301	29946801	WX	2	designed the experiments|analyzed the results and prepared the first draft of the manuscript|supervised the project	analyzed the results and prepared the first draft of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6038301	29946801	WX	2	designed the experiments|analyzed the results and prepared the first draft of the manuscript|supervised the project	supervised the project	-	Supervision	YES
6038301	29946801	XZ	2	edited and reviewed the draft	edited and reviewed the draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6038301	29946801	ZW	2	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5824557	29471804	CMH	2	analyzed data and contributed to the writing of the manuscript	analyzed data and contributed to the writing of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5824557	29471804	DSP	2	conceived the project, secured funding, contributed to the data analysis, and writing of the manuscript	conceived the project, secured funding, contributed to the data analysis, and writing of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Funding acquisition|Writing - Original Draft	YES
5824557	29471804	JRG	2	conceived the project, secured funding, and edited the manuscript	conceived the project, secured funding, and edited the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Funding acquisition|Writing - Review & Editing	YES
5824557	29471804	RRV	2	conceived the project, secured funding, and edited the manuscript	conceived the project, secured funding, and edited the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Funding acquisition|Writing - Review & Editing	YES
5824557	29471804	SJO	2	performed laboratory work, analyzed data, and contributed to the writing of the manuscript	performed laboratory work, analyzed data, and contributed to the writing of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4418746	25938590	ANF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418746	25938590	ANF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418746	25938590	ANF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418746	25938590	ANF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418746	25938590	CO	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418746	25938590	CO	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418746	25938590	CO	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418746	25938590	JC	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4418746	25938590	JC	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418746	25938590	MC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418746	25938590	MGH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418746	25938590	MGH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418746	25938590	MGH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418746	25938590	MGH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418746	25938590	XA	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418746	25938590	XA	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3721478	23716398	AAV	2	echocardiography in mice|serotype 6	echocardiography in mice	Performed the experiments	Investigation	YES
3721478	23716398	AAV	2	echocardiography in mice|serotype 6	serotype 6	-	-	NO
3721478	23716398	All authors	2	critically reviewed and approved the manuscript before submission	critically reviewed and approved the manuscript before submission	Wrote the paper	Writing - Review & Editing	YES
3721478	23716398	DS	2	cloned wild-type and mutant mybpc3 cdnas, isolated and transduced cardiac myocytes and performed immunofluoresence analysis	cloned wild-type and mutant mybpc3 cdnas, isolated and transduced cardiac myocytes and performed immunofluoresence analysis	Performed the experiments	Investigation	YES
3721478	23716398	GM	2	designed the cloning strategy of mutant mybpc3 cdnas and supervised ds	designed the cloning strategy of mutant mybpc3 cdnas and supervised ds	Conceived and designed the experiments|Performed the experiments	Investigation|Supervision	YES
3721478	23716398	GP	2	produced the aav serotype 9	produced the aav serotype 9	-	-	NO
3721478	23716398	LC	2	designed and supervised the entire study, obtained funding and finalized the manuscript	designed and supervised the entire study, obtained funding and finalized the manuscript	Conceived and designed the experiments|Wrote the paper	Funding acquisition|Methodology|Supervision|Writing - Review & Editing	YES
3721478	23716398	SL	2	contributed to the u7-aon strategy	contributed to the u7-aon strategy	-	-	NO
3721478	23716398	SR	2	performed rt pcrs and western blots	performed rt pcrs and western blots	Performed the experiments	Investigation	YES
3721478	23716398	SS	2	managed all the mouse cohorts	managed all the mouse cohorts	-	-	NO
3721478	23716398	TE	2	critically discussed the results and manuscript	critically discussed the results and manuscript	-	-	NO
3721478	23716398	TV	2	critically discussed the results	critically discussed the results	-	-	NO
3721478	23716398	VBG	2	cloned var-4 cdna, transduced cardiac myocytes, performed immunofluorescence and molecular analysis, and corrected the first draft of the manuscript	cloned var-4 cdna, transduced cardiac myocytes, performed immunofluorescence and molecular analysis, and corrected the first draft of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
4184442	25250878	G.L.	2	contributed equally	contributed equally	-	-	NO
4184442	25250878	Y.J.	2	contributed equally	contributed equally	-	-	NO
5836289	29541089	AD	2	significantly contributed on writing the manuscript	significantly contributed on writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5836289	29541089	AI	2	significantly contributed on writing the manuscript	significantly contributed on writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5836289	29541089	BB	2	performed the data analysis using the described the functional genomic, bioinformatics tools|significantly contributed on writing the manuscript	performed the data analysis using the described the functional genomic, bioinformatics tools	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5836289	29541089	BB	2	performed the data analysis using the described the functional genomic, bioinformatics tools|significantly contributed on writing the manuscript	significantly contributed on writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5836289	29541089	FM	2	conceived, designed the research work and mainly wrote the article|significantly contributed on writing the manuscript	conceived, designed the research work and mainly wrote the article	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Writing - Original Draft	YES
5836289	29541089	FM	2	conceived, designed the research work and mainly wrote the article|significantly contributed on writing the manuscript	significantly contributed on writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5836289	29541089	TC	2	significantly contributed on writing the manuscript	significantly contributed on writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5477679	28649385	AKB	2	contributed equally to the design, data acquisition and manuscript preparation	contributed equally to the design, data acquisition and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Resources|Writing - Original Draft	YES
5477679	28649385	RKS	2	contributed equally to the design, data acquisition and manuscript preparation	contributed equally to the design, data acquisition and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Resources|Writing - Original Draft	YES
5477679	28649385	SS	2	contributed equally to the design, data acquisition and manuscript preparation	contributed equally to the design, data acquisition and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Resources|Writing - Original Draft	YES
5836591	29541081	HL	2	performed the experiments, analyzed the data, and drafted the manuscript	performed the experiments, analyzed the data, and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5836591	29541081	JJ	2	helped to draft the manuscript	helped to draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5836591	29541081	XL	2	participated in the data analysis and wrote the manuscript	participated in the data analysis and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5836591	29541081	YW	2	contributed analysis tools and helped to draft the manuscript	contributed analysis tools and helped to draft the manuscript	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Writing - Original Draft	YES
5836591	29541081	YX	2	helped to draft the manuscript	helped to draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5836591	29541081	ZP	2	conceived the study, participated in its coordination, and helped to draft the manuscript	conceived the study, participated in its coordination, and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Project administration|Writing - Original Draft	YES
4378217	25820563	JY	2	research designed methods design	research designed methods design	Conceived and designed the experiments|Performed the experiments	Methodology	YES
4378217	25820563	WL	2	laboratory experiments, analysis interpretation and discussion of results, manuscript drafting	laboratory experiments, analysis interpretation and discussion of results, manuscript drafting	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
2031825	17957250	CE	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
2031825	17957250	CE	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2031825	17957250	DD	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2031825	17957250	DD	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2031825	17957250	DH	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2031825	17957250	DH	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2031825	17957250	DM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2031825	17957250	DM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2031825	17957250	DM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2031825	17957250	DM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5647280	28993497	C.P.K.	2	conceived the paper|for reviewing the molecular case studies in invertebrates|wrote the final version of the paper with input from all authors	conceived the paper	Conceived and designed the experiments	Conceptualization	YES
5647280	28993497	C.P.K.	2	conceived the paper|for reviewing the molecular case studies in invertebrates|wrote the final version of the paper with input from all authors	for reviewing the molecular case studies in invertebrates	Performed the experiments	Investigation	YES
5647280	28993497	C.P.K.	2	conceived the paper|for reviewing the molecular case studies in invertebrates|wrote the final version of the paper with input from all authors	wrote the final version of the paper with input from all authors	Wrote the paper	Writing - Original Draft	YES
5647280	28993497	M.B.	2	conceived the paper|drafted the shorebird introduction and discussion|wrote the final version of the paper with input from all authors	conceived the paper	Conceived and designed the experiments	Conceptualization	YES
5647280	28993497	M.B.	2	conceived the paper|drafted the shorebird introduction and discussion|wrote the final version of the paper with input from all authors	drafted the shorebird introduction and discussion	Wrote the paper	Writing - Original Draft	YES
5647280	28993497	M.B.	2	conceived the paper|drafted the shorebird introduction and discussion|wrote the final version of the paper with input from all authors	wrote the final version of the paper with input from all authors	Wrote the paper	Writing - Original Draft	YES
5647280	28993497	T.P.	2	conceived the paper	conceived the paper	Conceived and designed the experiments	Conceptualization	YES
4418749	25938492	DH	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418749	25938492	FL	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418749	25938492	FL	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418749	25938492	FL	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418749	25938492	JL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418749	25938492	JL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418749	25938492	JL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418749	25938492	JL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418749	25938492	JQ	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418749	25938492	JQ	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418749	25938492	JQ	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418749	25938492	JW	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418749	25938492	JW	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418749	25938492	JW	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418749	25938492	LH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418749	25938492	LH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418749	25938492	LH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418749	25938492	LH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418749	25938492	LH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418749	25938492	MP	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418749	25938492	MP	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418749	25938492	MP	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418749	25938492	MP	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418749	25938492	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418749	25938492	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418749	25938492	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418749	25938492	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418749	25938492	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418749	25938492	XZ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418749	25938492	XZ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418749	25938492	XZ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418749	25938492	XZ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418749	25938492	ZX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418749	25938492	ZX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418749	25938492	ZX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418749	25938492	ZX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418749	25938492	ZX	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6039347	29992363	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6039347	29992363	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
6039347	29992363	VR	2	performed the hydrolysis experiments|wrote the manuscript and all authors contributed to the data analysis and commented on the manuscript	performed the hydrolysis experiments	Performed the experiments	Investigation	YES
6039347	29992363	VR	2	performed the hydrolysis experiments|wrote the manuscript and all authors contributed to the data analysis and commented on the manuscript	wrote the manuscript and all authors contributed to the data analysis and commented on the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5836596	29541080	AL-O	2	conceived the study and secured federal grant to support research activities|designed all experiments|conducted experiments and collected data|analyzed the data, designed and constructed and characterized all the expression vectors utilized to recover transgenic cassava lines	conceived the study and secured federal grant to support research activities	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
5836596	29541080	AL-O	2	conceived the study and secured federal grant to support research activities|designed all experiments|conducted experiments and collected data|analyzed the data, designed and constructed and characterized all the expression vectors utilized to recover transgenic cassava lines	designed all experiments	Conceived and designed the experiments	Methodology	YES
5836596	29541080	AL-O	2	conceived the study and secured federal grant to support research activities|designed all experiments|conducted experiments and collected data|analyzed the data, designed and constructed and characterized all the expression vectors utilized to recover transgenic cassava lines	conducted experiments and collected data	Performed the experiments	Investigation	YES
5836596	29541080	AL-O	2	conceived the study and secured federal grant to support research activities|designed all experiments|conducted experiments and collected data|analyzed the data, designed and constructed and characterized all the expression vectors utilized to recover transgenic cassava lines	analyzed the data, designed and constructed and characterized all the expression vectors utilized to recover transgenic cassava lines	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5836596	29541080	BH	2	conceived the study and secured federal grant to support research activities|designed all experiments|conducted experiments and collected data|analyzed the data, designed and constructed and characterized all the expression vectors utilized to recover transgenic cassava lines|edited the manuscript	conceived the study and secured federal grant to support research activities	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
5836596	29541080	BH	2	conceived the study and secured federal grant to support research activities|designed all experiments|conducted experiments and collected data|analyzed the data, designed and constructed and characterized all the expression vectors utilized to recover transgenic cassava lines|edited the manuscript	designed all experiments	Conceived and designed the experiments	Methodology	YES
5836596	29541080	BH	2	conceived the study and secured federal grant to support research activities|designed all experiments|conducted experiments and collected data|analyzed the data, designed and constructed and characterized all the expression vectors utilized to recover transgenic cassava lines|edited the manuscript	conducted experiments and collected data	Performed the experiments	Investigation	YES
5836596	29541080	BH	2	conceived the study and secured federal grant to support research activities|designed all experiments|conducted experiments and collected data|analyzed the data, designed and constructed and characterized all the expression vectors utilized to recover transgenic cassava lines|edited the manuscript	analyzed the data, designed and constructed and characterized all the expression vectors utilized to recover transgenic cassava lines	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5836596	29541080	BH	2	conceived the study and secured federal grant to support research activities|designed all experiments|conducted experiments and collected data|analyzed the data, designed and constructed and characterized all the expression vectors utilized to recover transgenic cassava lines|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5836596	29541080	C-HW	2	conducted experiments and collected data|edited the manuscript	conducted experiments and collected data	Performed the experiments	Investigation	YES
5836596	29541080	C-HW	2	conducted experiments and collected data|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5836596	29541080	CV	2	conceived the study and secured federal grant to support research activities|designed all experiments|edited the manuscript	conceived the study and secured federal grant to support research activities	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
5836596	29541080	CV	2	conceived the study and secured federal grant to support research activities|designed all experiments|edited the manuscript	designed all experiments	Conceived and designed the experiments	Methodology	YES
5836596	29541080	CV	2	conceived the study and secured federal grant to support research activities|designed all experiments|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5836596	29541080	ED	2	conducted experiments and collected data	conducted experiments and collected data	Performed the experiments	Investigation	YES
5836596	29541080	FP	2	designed all experiments|conducted experiments and collected data|edited the manuscript	designed all experiments	Conceived and designed the experiments	Methodology	YES
5836596	29541080	FP	2	designed all experiments|conducted experiments and collected data|edited the manuscript	conducted experiments and collected data	Performed the experiments	Investigation	YES
5836596	29541080	FP	2	designed all experiments|conducted experiments and collected data|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5836596	29541080	JJ	2	conducted experiments and collected data	conducted experiments and collected data	Performed the experiments	Investigation	YES
5836596	29541080	MA	2	conceived the study and secured federal grant to support research activities|designed all experiments|edited the manuscript	conceived the study and secured federal grant to support research activities	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
5836596	29541080	MA	2	conceived the study and secured federal grant to support research activities|designed all experiments|edited the manuscript	designed all experiments	Conceived and designed the experiments	Methodology	YES
5836596	29541080	MA	2	conceived the study and secured federal grant to support research activities|designed all experiments|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5836596	29541080	SC	2	conducted experiments and collected data|edited the manuscript	conducted experiments and collected data	Performed the experiments	Investigation	YES
5836596	29541080	SC	2	conducted experiments and collected data|edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
6270879	24962386	Wan-Rong Huang	PLoS52	performed research and wrote the paper	performed research and wrote the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6270879	24962386	Xin Tang	PLoS52	designed research	designed research	Conceived and designed the experiments	Methodology	YES
6270879	24962386	Yue Zhang	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5824572	29471801	All authors	2	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5824572	29471801	JC	2	conceived the project|evaluated the results, and wrote the manuscripts	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5824572	29471801	JC	2	conceived the project|evaluated the results, and wrote the manuscripts	evaluated the results, and wrote the manuscripts	Wrote the paper	Writing - Original Draft	YES
5824572	29471801	OO	2	designed the algorithm|implemented the algorithm|performed the statistical and simulation analyses|evaluated the results, and wrote the manuscripts	designed the algorithm	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
5824572	29471801	OO	2	designed the algorithm|implemented the algorithm|performed the statistical and simulation analyses|evaluated the results, and wrote the manuscripts	implemented the algorithm	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5824572	29471801	OO	2	designed the algorithm|implemented the algorithm|performed the statistical and simulation analyses|evaluated the results, and wrote the manuscripts	performed the statistical and simulation analyses	Analyzed the data	Formal analysis	YES
5824572	29471801	OO	2	designed the algorithm|implemented the algorithm|performed the statistical and simulation analyses|evaluated the results, and wrote the manuscripts	evaluated the results, and wrote the manuscripts	Wrote the paper	Writing - Original Draft	YES
5824572	29471801	YZ	2	designed the algorithm|evaluated the results, and wrote the manuscripts	designed the algorithm	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Software	YES
5824572	29471801	YZ	2	designed the algorithm|evaluated the results, and wrote the manuscripts	evaluated the results, and wrote the manuscripts	Wrote the paper	Writing - Original Draft	YES
5490178	28680640	All the authors	2	have contributed sufficiently to this work to be included as authors	have contributed sufficiently to this work to be included as authors	-	-	NO
5490178	28680640	CS	2	conceived and coordinated the study	conceived and coordinated the study	Conceived and designed the experiments	Conceptualization|Project administration	YES
2031826	17957247	AB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
2031826	17957247	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2031826	17957247	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
2031826	17957247	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2031826	17957247	DF	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
2031826	17957247	DF	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2031826	17957247	DO	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2031826	17957247	DO	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2031826	17957247	GJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2031826	17957247	GJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
2031826	17957247	GJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2031826	17957247	JA	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
2031826	17957247	JU	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2031826	17957247	JU	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2031826	17957247	JW	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
2031826	17957247	JW	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2031826	17957247	MS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2031826	17957247	MS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2031826	17957247	SC	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
2031826	17957247	SC	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2031826	17957247	TR	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2031826	17957247	WW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2031826	17957247	WW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2031826	17957247	WW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2031826	17957247	WW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5496228	28690852	LF	2	helped in editing the manuscript	helped in editing the manuscript	Wrote the paper	Writing - Review & Editing	YES
5496228	28690852	TI	2	had the concept of the study	had the concept of the study	Conceived and designed the experiments	Conceptualization	YES
4418752	25938228	BDA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418752	25938228	BDA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418752	25938228	BDA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418752	25938228	BDA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418752	25938228	BDA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418752	25938228	CY	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418752	25938228	MLH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418752	25938228	MLH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418752	25938228	MLH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418752	25938228	MLH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418752	25938228	MLH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418752	25938228	SNH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418752	25938228	SNH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418752	25938228	SNH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418752	25938228	SNH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4663286	26649302	Jie Zhou	2	contributed equally to this work	contributed equally to this work	-	-	NO
4663286	26649302	Xiang-Yan Chen	2	contributed equally to this work	contributed equally to this work	-	-	NO
2031827	17957246	DR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2031827	17957246	DR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2031827	17957246	DR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2031827	17957246	DR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2031827	17957246	GA	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2031827	17957246	GA	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2031827	17957246	GA	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2031827	17957246	LT	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2031827	17957246	LT	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2031827	17957246	LT	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2031827	17957246	MD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2031827	17957246	MD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2031827	17957246	MD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2031827	17957246	NT	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2031827	17957246	NT	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2031827	17957246	NT	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5837998	29545820	All	2	the persons entitled to authorship have been named and have approved the final version of the submitted manuscript	the persons entitled to authorship have been named and have approved the final version of the submitted manuscript	-	-	NO
5837998	29545820	LL	2	supervised and complemented the drafting	supervised and complemented the drafting	Wrote the paper	Supervision|Writing - Original Draft	YES
5837998	29545820	MN	2	drew figures and collaborated in writing the manuscript	drew figures and collaborated in writing the manuscript	Wrote the paper	Visualization|Writing - Original Draft	YES
5837998	29545820	NC-A	2	supervised and complemented the drafting	supervised and complemented the drafting	Wrote the paper	Supervision|Writing - Original Draft	YES
5837998	29545820	RC	2	conceived the project and wrote the manuscript	conceived the project and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
3913091	24526882	All authors	2	have a significant scientific input into the work	have a significant scientific input into the work	-	-	NO
5504563	28702197	HI	2	helped draft the manuscript	helped draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5504563	28702197	KH	2	drafted the manuscript, participated in the study design, and performed the statistics analysis	drafted the manuscript, participated in the study design, and performed the statistics analysis	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5504563	28702197	NM	2	helped draft the manuscript	helped draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5504563	28702197	TK	2	helped draft the manuscript	helped draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5504563	28702197	YI	2	helped draft the manuscript	helped draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5504563	28702197	YK	2	helped draft the manuscript	helped draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5504563	28702197	YN	2	helped draft the manuscript	helped draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5824581	29471790	AV	2	are responsible for project planning|performed all experimental work|all contributed to the final version of the manuscript	are responsible for project planning	Conceived and designed the experiments	Methodology	YES
5824581	29471790	AV	2	are responsible for project planning|performed all experimental work|all contributed to the final version of the manuscript	performed all experimental work	Performed the experiments	Investigation	YES
5824581	29471790	AV	2	are responsible for project planning|performed all experimental work|all contributed to the final version of the manuscript	all contributed to the final version of the manuscript	-	-	NO
5824581	29471790	CJL	2	are responsible for project planning|is responsible for funding and providing oyster growing facilities|all contributed to the final version of the manuscript	are responsible for project planning	Conceived and designed the experiments	Methodology	YES
5824581	29471790	CJL	2	are responsible for project planning|is responsible for funding and providing oyster growing facilities|all contributed to the final version of the manuscript	is responsible for funding and providing oyster growing facilities	-	Funding acquisition	YES
5824581	29471790	CJL	2	are responsible for project planning|is responsible for funding and providing oyster growing facilities|all contributed to the final version of the manuscript	all contributed to the final version of the manuscript	-	-	NO
5824581	29471790	ED	2	are responsible for project planning|performed all experimental work|is responsible for water chemistry and microscopic analyses|all contributed to the final version of the manuscript	are responsible for project planning	Conceived and designed the experiments	Methodology	YES
5824581	29471790	ED	2	are responsible for project planning|performed all experimental work|is responsible for water chemistry and microscopic analyses|all contributed to the final version of the manuscript	performed all experimental work	Performed the experiments	Investigation	YES
5824581	29471790	ED	2	are responsible for project planning|performed all experimental work|is responsible for water chemistry and microscopic analyses|all contributed to the final version of the manuscript	is responsible for water chemistry and microscopic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5824581	29471790	ED	2	are responsible for project planning|performed all experimental work|is responsible for water chemistry and microscopic analyses|all contributed to the final version of the manuscript	all contributed to the final version of the manuscript	-	-	NO
5824581	29471790	PDW	2	are responsible for project planning|performed all experimental work|is responsible for all transcriptomic analyses and manuscript writing|all contributed to the final version of the manuscript	are responsible for project planning	Conceived and designed the experiments	Methodology	YES
5824581	29471790	PDW	2	are responsible for project planning|performed all experimental work|is responsible for all transcriptomic analyses and manuscript writing|all contributed to the final version of the manuscript	performed all experimental work	Performed the experiments	Investigation	YES
5824581	29471790	PDW	2	are responsible for project planning|performed all experimental work|is responsible for all transcriptomic analyses and manuscript writing|all contributed to the final version of the manuscript	is responsible for all transcriptomic analyses and manuscript writing	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5824581	29471790	PDW	2	are responsible for project planning|performed all experimental work|is responsible for all transcriptomic analyses and manuscript writing|all contributed to the final version of the manuscript	all contributed to the final version of the manuscript	-	-	NO
6039348	29992450	AZK	2	helped in conducting research work	helped in conducting research work	Performed the experiments	Investigation	YES
6039348	29992450	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6039348	29992450	FAS	2	provided a technical help in the writeup of this manuscript	provided a technical help in the writeup of this manuscript	Wrote the paper	Writing - Original Draft	YES
6039348	29992450	FG	2	helped in conducting research work	helped in conducting research work	Performed the experiments	Investigation	YES
6039348	29992450	FP	2	helped in conducting research work	helped in conducting research work	Performed the experiments	Investigation	YES
6039348	29992450	KH	2	designed study plan, collected literature and drafted the manuscript|reviewed and performed the final check	designed study plan, collected literature and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
6039348	29992450	KH	2	designed study plan, collected literature and drafted the manuscript|reviewed and performed the final check	reviewed and performed the final check	Performed the experiments	Investigation	YES
6039348	29992450	MEAE	2	provided a technical help in the writeup of this manuscript	provided a technical help in the writeup of this manuscript	Wrote the paper	Writing - Original Draft	YES
6039348	29992450	MH	2	helped in conducting research work	helped in conducting research work	Performed the experiments	Investigation	YES
6039348	29992450	SAN	2	helped in conducting research work	helped in conducting research work	Performed the experiments	Investigation	YES
6039348	29992450	SK	2	designed study plan, collected literature and drafted the manuscript	designed study plan, collected literature and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
6039348	29992450	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
6039348	29992450	YL	2	helped in conducting research work	helped in conducting research work	Performed the experiments	Investigation	YES
6039348	29992450	ZAN	2	provided a technical help in the writeup of this manuscript	provided a technical help in the writeup of this manuscript	Wrote the paper	Writing - Original Draft	YES
4418754	25938484	CFW	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418754	25938484	FRL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418754	25938484	JHW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418754	25938484	JHW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418754	25938484	JHW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418754	25938484	JP	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418754	25938484	JPY	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418754	25938484	LXG	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418754	25938484	LXG	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418754	25938484	LXG	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418754	25938484	LXG	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418754	25938484	XMX	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
2031828	17957256	GY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2031828	17957256	GY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2031828	17957256	GY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2031828	17957256	GY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2031828	17957256	GY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2031828	17957256	HZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
2031828	17957256	PG	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
2031828	17957256	PG	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2031828	17957256	SH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2031828	17957256	SH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2031828	17957256	SH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2031828	17957256	SH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2031828	17957256	ZZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2031828	17957256	ZZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2031828	17957256	ZZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2031828	17957256	ZZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5838007	29545816	AA	CRediT7	writing - original draft. ML-M|writing - review and editing|funding acquisition	writing - original draft. ML-M	Wrote the paper	Writing - Original Draft	YES
5838007	29545816	AA	CRediT7	writing - original draft. ML-M|writing - review and editing|funding acquisition	writing - review and editing	Wrote the paper	Writing - Review & Editing	YES
5838007	29545816	AA	CRediT7	writing - original draft. ML-M|writing - review and editing|funding acquisition	funding acquisition	-	Funding acquisition	YES
5838007	29545816	LP	CRediT7	conceptualization|methodology|investigation|formal analysis and visualization|writing - original draft. ML-M	conceptualization	Conceived and designed the experiments	Conceptualization	YES
5838007	29545816	LP	CRediT7	conceptualization|methodology|investigation|formal analysis and visualization|writing - original draft. ML-M	methodology	Performed the experiments	Methodology	YES
5838007	29545816	LP	CRediT7	conceptualization|methodology|investigation|formal analysis and visualization|writing - original draft. ML-M	investigation	Performed the experiments	Investigation	YES
5838007	29545816	LP	CRediT7	conceptualization|methodology|investigation|formal analysis and visualization|writing - original draft. ML-M	formal analysis and visualization	Analyzed the data	Formal analysis|Visualization	YES
5838007	29545816	LP	CRediT7	conceptualization|methodology|investigation|formal analysis and visualization|writing - original draft. ML-M	writing - original draft. ML-M	Wrote the paper	Writing - Original Draft	YES
5838007	29545816	MB	CRediT7	writing - review and editing	writing - review and editing	Wrote the paper	Writing - Review & Editing	YES
5838007	29545816	ML-M	CRediT7	conceptualization|methodology|investigation	conceptualization	Conceived and designed the experiments	Conceptualization	YES
5838007	29545816	ML-M	CRediT7	conceptualization|methodology|investigation	methodology	Performed the experiments	Methodology	YES
5838007	29545816	ML-M	CRediT7	conceptualization|methodology|investigation	investigation	Performed the experiments	Investigation	YES
5838007	29545816	SS	CRediT7	methodology|investigation|writing - review and editing	methodology	Performed the experiments	Methodology	YES
5838007	29545816	SS	CRediT7	methodology|investigation|writing - review and editing	investigation	Performed the experiments	Investigation	YES
5838007	29545816	SS	CRediT7	methodology|investigation|writing - review and editing	writing - review and editing	Wrote the paper	Writing - Review & Editing	YES
5838007	29545816	TM	CRediT7	investigation	investigation	Performed the experiments	Investigation	YES
6270881	25232703	All the authors	PLoS52	were performed research and analysis of data for presented study	were performed research and analysis of data for presented study	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270881	25232703	Aneta Balcerczyk	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270881	25232703	Grzegorz Bartosz	PLoS52	were involved in design the study	were involved in design the study	Conceived and designed the experiments	Methodology	YES
6270881	25232703	Janusz Szemraj	PLoS52	were involved in design the study|wrote the paper	were involved in design the study	Conceived and designed the experiments	Methodology	YES
6270881	25232703	Janusz Szemraj	PLoS52	were involved in design the study|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4503964	26150151	IJ	2	data collection, analysis and interpretation of data|manuscript drafting	data collection, analysis and interpretation of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4503964	26150151	IJ	2	data collection, analysis and interpretation of data|manuscript drafting	manuscript drafting	Wrote the paper	Writing - Original Draft	YES
4503964	26150151	IK	2	study concept and design|data collection, analysis and interpretation of data	study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4503964	26150151	IK	2	study concept and design|data collection, analysis and interpretation of data	data collection, analysis and interpretation of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5504755	28702196	CH	2	did the literature review, data analysis and the development of the manuscript and its editing	did the literature review, data analysis and the development of the manuscript and its editing	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5504755	28702196	EL	2	did the literature review, data analysis and the development of the manuscript and its editing	did the literature review, data analysis and the development of the manuscript and its editing	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5504755	28702196	FvH	2	did the literature review, data analysis and the development of the manuscript and its editing	did the literature review, data analysis and the development of the manuscript and its editing	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5504755	28702196	LJD	2	did the literature review, data analysis and the development of the manuscript and its editing	did the literature review, data analysis and the development of the manuscript and its editing	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5504755	28702196	MC	2	did the literature review, data analysis and the development of the manuscript and its editing	did the literature review, data analysis and the development of the manuscript and its editing	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5504755	28702196	VL	2	did the literature review, data analysis and the development of the manuscript and its editing	did the literature review, data analysis and the development of the manuscript and its editing	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
6039349	29992518	ADP	PLoS52	conceived and designed the experiments|performed the extraction and analysis of fatty acids, carotenoids and isoprenoid quinones	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6039349	29992518	ADP	PLoS52	conceived and designed the experiments|performed the extraction and analysis of fatty acids, carotenoids and isoprenoid quinones	performed the extraction and analysis of fatty acids, carotenoids and isoprenoid quinones	Performed the experiments	Investigation	YES
6039349	29992518	AT	PLoS52	performed the isolation and identification of microorganisms|performed the emulsification activity	performed the isolation and identification of microorganisms	Performed the experiments	Investigation	YES
6039349	29992518	AT	PLoS52	performed the isolation and identification of microorganisms|performed the emulsification activity	performed the emulsification activity	Performed the experiments	Investigation	YES
6039349	29992518	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6039349	29992518	DR	PLoS52	performed the characterization of the bioemulsifier	performed the characterization of the bioemulsifier	Performed the experiments	Investigation	YES
6039349	29992518	GDB	PLoS52	conceived and designed the experiments|performed the characterization of the bioemulsifier|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6039349	29992518	GDB	PLoS52	conceived and designed the experiments|performed the characterization of the bioemulsifier|wrote the paper	performed the characterization of the bioemulsifier	Performed the experiments	Investigation	YES
6039349	29992518	GDB	PLoS52	conceived and designed the experiments|performed the characterization of the bioemulsifier|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6039349	29992518	GM	PLoS52	conceived and designed the experiments|performed the extraction and analysis of fatty acids, carotenoids and isoprenoid quinones	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6039349	29992518	GM	PLoS52	conceived and designed the experiments|performed the extraction and analysis of fatty acids, carotenoids and isoprenoid quinones	performed the extraction and analysis of fatty acids, carotenoids and isoprenoid quinones	Performed the experiments	Investigation	YES
6039349	29992518	GP	PLoS52	performed the isolation and identification of microorganisms	performed the isolation and identification of microorganisms	Performed the experiments	Investigation	YES
6039349	29992518	MD	PLoS52	performed the extraction and analysis of fatty acids, carotenoids and isoprenoid quinones	performed the extraction and analysis of fatty acids, carotenoids and isoprenoid quinones	Performed the experiments	Investigation	YES
6039349	29992518	MDS	PLoS52	performed the emulsification activity	performed the emulsification activity	Performed the experiments	Investigation	YES
6039349	29992518	MF	PLoS52	performed the extraction and analysis of fatty acids, carotenoids and isoprenoid quinones	performed the extraction and analysis of fatty acids, carotenoids and isoprenoid quinones	Performed the experiments	Investigation	YES
6039349	29992518	PA	PLoS52	conceived and designed the experiments|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6039349	29992518	PA	PLoS52	conceived and designed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6039349	29992518	Roberta Romano	PLoS52	for technical support	for technical support	Performed the experiments	Investigation	YES
6039349	29992518	SMT	PLoS52	performed the isolation and identification of microorganisms	performed the isolation and identification of microorganisms	Performed the experiments	Investigation	YES
6039349	29992518	Sudipto Pal	PLoS52	and prof	and prof	-	-	NO
6039349	29992518	The authors	PLoS52	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5824590	29471803	All the authors	2	have reviewed the final version of the manuscript and approved it for publication	have reviewed the final version of the manuscript and approved it for publication	Wrote the paper	Writing - Review & Editing	YES
5824590	29471803	B.L.L.	2	conceived the idea and research plans|performed the experiments, analyzed the data and drafted the manuscript	conceived the idea and research plans	Conceived and designed the experiments	Conceptualization	YES
5824590	29471803	B.L.L.	2	conceived the idea and research plans|performed the experiments, analyzed the data and drafted the manuscript	performed the experiments, analyzed the data and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5824590	29471803	F.L.	2	provided technical assistance to b	provided technical assistance to b	Performed the experiments	Investigation	YES
5824590	29471803	G.H.X.	2	supervised the experiments	supervised the experiments	-	Supervision	YES
5824590	29471803	J.D.C.	2	provided technical assistance to b	provided technical assistance to b	Performed the experiments	Investigation	YES
5824590	29471803	J.K.R.	2	supervised the experiments	supervised the experiments	-	Supervision	YES
5824590	29471803	T.Z.Z.	2	conceived the idea and research plans|conceptualized the research program and revised the manuscript	conceived the idea and research plans	Conceived and designed the experiments	Conceptualization	YES
5824590	29471803	T.Z.Z.	2	conceived the idea and research plans|conceptualized the research program and revised the manuscript	conceptualized the research program and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5824590	29471803	W.H.L.	2	provided technical assistance to b	provided technical assistance to b	Performed the experiments	Investigation	YES
5824590	29471803	W.Z.G.	2	supervised the experiments	supervised the experiments	-	Supervision	YES
5824590	29471803	X.Y.G.	2	supervised the experiments	supervised the experiments	-	Supervision	YES
5824590	29471803	Y.H.	2	supervised the experiments	supervised the experiments	-	Supervision	YES
4418755	25938413	JSL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4418755	25938413	JSL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4418755	25938413	JSL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418755	25938413	MGP	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418755	25938413	MGP	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418755	25938413	MSR	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418755	25938413	MSR	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418755	25938413	MSR	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418755	25938413	MSR	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418755	25938413	SJY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418755	25938413	SJY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418755	25938413	SJY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418755	25938413	SJY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418755	25938413	SJY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418755	25938413	WSK	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418755	25938413	WSK	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418755	25938413	WSK	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418755	25938413	WSK	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270882	24968329	Ali Aldalbahi	2	carried out the synthesis and edited the english language	carried out the synthesis and edited the english language	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
6270882	24968329	Assem Barakat	2	wrote some research and audit	wrote some research and audit	Wrote the paper	Writing - Original Draft	YES
6270882	24968329	Fahad D. Aldawsari	2	students did the experiments	students did the experiments	Performed the experiments	Investigation	YES
6270882	24968329	Munirah S. Al-Har	2	students did the experiments	students did the experiments	Performed the experiments	Investigation	YES
6270882	24968329	Yahia N. Mabkhot	2	designed the study, carried out the synthesis	designed the study, carried out the synthesis	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6270882	24968329	Zaheer-Ul-Haq	2	carried out molecular docking studies	carried out molecular docking studies	Performed the experiments	Investigation	YES
5508707	28717513	AW	2	conceived the study and design|performed the data collection|oversaw the conduct of the trial|managed the data, including quality control|drafted the manuscript, and all authors contributed substantially to its revision	conceived the study and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5508707	28717513	AW	2	conceived the study and design|performed the data collection|oversaw the conduct of the trial|managed the data, including quality control|drafted the manuscript, and all authors contributed substantially to its revision	performed the data collection	Performed the experiments	Investigation	YES
5508707	28717513	AW	2	conceived the study and design|performed the data collection|oversaw the conduct of the trial|managed the data, including quality control|drafted the manuscript, and all authors contributed substantially to its revision	oversaw the conduct of the trial	Performed the experiments	Investigation|Supervision	YES
5508707	28717513	AW	2	conceived the study and design|performed the data collection|oversaw the conduct of the trial|managed the data, including quality control|drafted the manuscript, and all authors contributed substantially to its revision	managed the data, including quality control	Performed the experiments|Analyzed the data	Data curation|Validation	YES
5508707	28717513	AW	2	conceived the study and design|performed the data collection|oversaw the conduct of the trial|managed the data, including quality control|drafted the manuscript, and all authors contributed substantially to its revision	drafted the manuscript, and all authors contributed substantially to its revision	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5508707	28717513	CS	2	conceived the study and design	conceived the study and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5508707	28717513	CT	2	conceived the study and design	conceived the study and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5508707	28717513	GW	2	conceived the study and design|performed the data collection|oversaw the conduct of the trial|managed the data, including quality control|drafted the manuscript, and all authors contributed substantially to its revision|takes responsibility for the paper as a whole	conceived the study and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5508707	28717513	GW	2	conceived the study and design|performed the data collection|oversaw the conduct of the trial|managed the data, including quality control|drafted the manuscript, and all authors contributed substantially to its revision|takes responsibility for the paper as a whole	performed the data collection	Performed the experiments	Investigation	YES
5508707	28717513	GW	2	conceived the study and design|performed the data collection|oversaw the conduct of the trial|managed the data, including quality control|drafted the manuscript, and all authors contributed substantially to its revision|takes responsibility for the paper as a whole	oversaw the conduct of the trial	Performed the experiments	Investigation|Supervision	YES
5508707	28717513	GW	2	conceived the study and design|performed the data collection|oversaw the conduct of the trial|managed the data, including quality control|drafted the manuscript, and all authors contributed substantially to its revision|takes responsibility for the paper as a whole	managed the data, including quality control	Performed the experiments|Analyzed the data	Data curation|Validation	YES
5508707	28717513	GW	2	conceived the study and design|performed the data collection|oversaw the conduct of the trial|managed the data, including quality control|drafted the manuscript, and all authors contributed substantially to its revision|takes responsibility for the paper as a whole	drafted the manuscript, and all authors contributed substantially to its revision	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5508707	28717513	GW	2	conceived the study and design|performed the data collection|oversaw the conduct of the trial|managed the data, including quality control|drafted the manuscript, and all authors contributed substantially to its revision|takes responsibility for the paper as a whole	takes responsibility for the paper as a whole	-	-	NO
5508707	28717513	JB	2	provided the statistical advice	provided the statistical advice	Analyzed the data	Formal analysis	YES
5508707	28717513	JV	2	provided the statistical advice	provided the statistical advice	Analyzed the data	Formal analysis	YES
5508707	28717513	PF	2	performed the data collection	performed the data collection	Performed the experiments	Investigation	YES
5508707	28717513	RS	2	conceived the study and design	conceived the study and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5508707	28717513	VT	2	conceived the study and design|performed the data collection|oversaw the conduct of the trial|managed the data, including quality control	conceived the study and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5508707	28717513	VT	2	conceived the study and design|performed the data collection|oversaw the conduct of the trial|managed the data, including quality control	performed the data collection	Performed the experiments	Investigation	YES
5508707	28717513	VT	2	conceived the study and design|performed the data collection|oversaw the conduct of the trial|managed the data, including quality control	oversaw the conduct of the trial	Performed the experiments	Investigation|Supervision	YES
5508707	28717513	VT	2	conceived the study and design|performed the data collection|oversaw the conduct of the trial|managed the data, including quality control	managed the data, including quality control	Performed the experiments|Analyzed the data	Data curation|Validation	YES
4503965	26150152	all authors	2	contributed to this work and approved the final version of the manuscript	contributed to this work and approved the final version of the manuscript	-	-	NO
5698621	29109222	All authors	2	helped with edits and revisions	helped with edits and revisions	Wrote the paper	Writing - Review & Editing	YES
5698621	29109222	C.R.	2	aided in conducting the experiment and statistical analysis	aided in conducting the experiment and statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5698621	29109222	L.S.S.	2	designed and funded the experiment|conducted the literature review and wrote the manuscript	designed and funded the experiment	Conceived and designed the experiments	Funding acquisition|Methodology	YES
5698621	29109222	L.S.S.	2	designed and funded the experiment|conducted the literature review and wrote the manuscript	conducted the literature review and wrote the manuscript	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5698621	29109222	R.M.G.	2	conducted the literature review and wrote the manuscript	conducted the literature review and wrote the manuscript	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5698621	29109222	S.S.	2	conducted the statistical analyses and helped write the manuscript	conducted the statistical analyses and helped write the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5838012	29545812	BK	2	designed and performed the research, wrote the paper and approved it for submission	designed and performed the research, wrote the paper and approved it for submission	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5838012	29545812	JG	2	designed and performed the research, wrote the paper and approved it for submission	designed and performed the research, wrote the paper and approved it for submission	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5838012	29545812	PC	2	designed and performed the research, wrote the paper and approved it for submission	designed and performed the research, wrote the paper and approved it for submission	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
6047951	30014174	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6047951	30014174	BSS	2	involved in data analysis, manuscript preparation, critical review of the results	involved in data analysis, manuscript preparation, critical review of the results	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
6047951	30014174	CC	2	involved in the designing of the experiments, analysis of data, and support the manuscript writing	involved in the designing of the experiments, analysis of data, and support the manuscript writing	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
6047951	30014174	NK	2	participated in the rsm study, and statistical analysis	participated in the rsm study, and statistical analysis	Analyzed the data	Formal analysis	YES
6047951	30014174	NL	2	participated in the rsm study, and statistical analysis	participated in the rsm study, and statistical analysis	Analyzed the data	Formal analysis	YES
6047951	30014174	SP	2	was responsible for acquiring the raw experimental data and processing	was responsible for acquiring the raw experimental data and processing	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
6047951	30014174	SS	2	participated in the rsm study, and statistical analysis	participated in the rsm study, and statistical analysis	Analyzed the data	Formal analysis	YES
5831830	29490607	All authors	2	revised the manuscript and read and approved the final manuscript	revised the manuscript and read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5831830	29490607	CB	2	contributed to the selection of parent cells and generation of f2-segregants	contributed to the selection of parent cells and generation of f2-segregants	Performed the experiments	Investigation	YES
5831830	29490607	CC	2	contributed to the phenotyping of strains|contributed with the with	contributed to the phenotyping of strains	Performed the experiments	Investigation	YES
5831830	29490607	CC	2	contributed to the phenotyping of strains|contributed with the with	contributed with the with	-	-	NO
5831830	29490607	IS	2	established and performed the linkage analysis	established and performed the linkage analysis	Performed the experiments	Investigation	YES
5831830	29490607	JLL	2	analyzed the genotyping data|contributed with the with	analyzed the genotyping data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5831830	29490607	JLL	2	analyzed the genotyping data|contributed with the with	contributed with the with	-	-	NO
5831830	29490607	ME	2	conducted the experiments, contributed to the linkage analysis and wrote the manuscript	conducted the experiments, contributed to the linkage analysis and wrote the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5831830	29490607	SD	2	conceived and planned the study, with	conceived and planned the study, with	Conceived and designed the experiments	Conceptualization	YES
4418756	25938467	ADJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418756	25938467	ADJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4418756	25938467	ADJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418756	25938467	BWS	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418756	25938467	CSJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418756	25938467	CSJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418756	25938467	CSJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418756	25938467	CSJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418756	25938467	FE	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418756	25938467	FE	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418756	25938467	LF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418756	25938467	LF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418756	25938467	LF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418756	25938467	LF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418756	25938467	LF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418756	25938467	MHH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418756	25938467	MHH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418756	25938467	MHH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418756	25938467	MHH	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418756	25938467	MSN	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418756	25938467	MSN	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418756	25938467	PHK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418756	25938467	PHK	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418756	25938467	RR	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418756	25938467	RR	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
2031917	17957261	AC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
2031917	17957261	CT	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2031917	17957261	CT	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2031917	17957261	JC	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2031917	17957261	JC	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2031917	17957261	NN	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2031917	17957261	NN	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2031917	17957261	NN	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2031917	17957261	PB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
2031917	17957261	PC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
2031917	17957261	PF	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
3779446	23681708	ACDase	2	enzyme and performed the liposome assay	enzyme and performed the liposome assay	Performed the experiments	Investigation	YES
3779446	23681708	AMA	2	designed the study|analyzed the data and wrote the manuscript|performed most of the experiments|designed the targeting vector and the knock-in experiments|did the electron microscopy examinations|analyzed the tissues for mcp-1 levels by elisa	designed the study	Conceived and designed the experiments	Methodology	YES
3779446	23681708	AMA	2	designed the study|analyzed the data and wrote the manuscript|performed most of the experiments|designed the targeting vector and the knock-in experiments|did the electron microscopy examinations|analyzed the tissues for mcp-1 levels by elisa	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3779446	23681708	AMA	2	designed the study|analyzed the data and wrote the manuscript|performed most of the experiments|designed the targeting vector and the knock-in experiments|did the electron microscopy examinations|analyzed the tissues for mcp-1 levels by elisa	performed most of the experiments	Performed the experiments	Investigation	YES
3779446	23681708	AMA	2	designed the study|analyzed the data and wrote the manuscript|performed most of the experiments|designed the targeting vector and the knock-in experiments|did the electron microscopy examinations|analyzed the tissues for mcp-1 levels by elisa	designed the targeting vector and the knock-in experiments	Conceived and designed the experiments	Methodology	YES
3779446	23681708	AMA	2	designed the study|analyzed the data and wrote the manuscript|performed most of the experiments|designed the targeting vector and the knock-in experiments|did the electron microscopy examinations|analyzed the tissues for mcp-1 levels by elisa	did the electron microscopy examinations	Performed the experiments	Investigation	YES
3779446	23681708	AMA	2	designed the study|analyzed the data and wrote the manuscript|performed most of the experiments|designed the targeting vector and the knock-in experiments|did the electron microscopy examinations|analyzed the tissues for mcp-1 levels by elisa	analyzed the tissues for mcp-1 levels by elisa	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3779446	23681708	CMS	2	performed the analyses on the ovaries	performed the analyses on the ovaries	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3779446	23681708	EHS	2	performed the analyses on the ovaries	performed the analyses on the ovaries	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3779446	23681708	GF	2	performed the mass spectrometry analyses of ceramide	performed the mass spectrometry analyses of ceramide	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3779446	23681708	JAM	2	designed the study|analyzed the data and wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
3779446	23681708	JAM	2	designed the study|analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3779446	23681708	JC	2	performed the mass spectrometry analyses of ceramide	performed the mass spectrometry analyses of ceramide	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3779446	23681708	MJE	2	analyzed the tissues for mcp-1 levels by elisa	analyzed the tissues for mcp-1 levels by elisa	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3779446	23681708	PVT	2	conducted the histopathology examinations	conducted the histopathology examinations	Performed the experiments	Investigation	YES
3779446	23681708	RH	2	designed the targeting vector and the knock-in experiments	designed the targeting vector and the knock-in experiments	Conceived and designed the experiments	Methodology	YES
3779446	23681708	SD	2	did the electron microscopy examinations	did the electron microscopy examinations	Performed the experiments	Investigation	YES
3779446	23681708	SEG	2	designed the targeting vector and the knock-in experiments	designed the targeting vector and the knock-in experiments	Conceived and designed the experiments	Methodology	YES
3779446	23681708	TL	2	analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4503966	26150153	BY	2	participation in study design, data collection, analysis of data and manuscript preparation	participation in study design, data collection, analysis of data and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4503966	26150153	JW	2	contributed equally to this work|experimental work, data collection and interpretation	contributed equally to this work	-	-	NO
4503966	26150153	JW	2	contributed equally to this work|experimental work, data collection and interpretation	experimental work, data collection and interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4503966	26150153	QL	2	study design, data analysis and interpretation, manuscript drafting	study design, data analysis and interpretation, manuscript drafting	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4503966	26150153	XC	2	participation in experimental work design and coordination, data acquisition	participation in experimental work design and coordination, data acquisition	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Project administration	YES
4503966	26150153	XZ	2	study design, data analysis and interpretation, manuscript drafting	study design, data analysis and interpretation, manuscript drafting	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4503966	26150153	YZ	2	contributed equally to this work|experimental work, data collection and interpretation	contributed equally to this work	-	-	NO
4503966	26150153	YZ	2	contributed equally to this work|experimental work, data collection and interpretation	experimental work, data collection and interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270883	25350364	AMJ	2	designed the review, coordinated the review, and drafted the manuscript	designed the review, coordinated the review, and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Project administration|Writing - Original Draft|Writing - Review & Editing	YES
6270883	25350364	IC	2	designed the review, coordinated the review, and drafted the manuscript	designed the review, coordinated the review, and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Project administration|Writing - Original Draft|Writing - Review & Editing	YES
6270883	25350364	The authors	2	contributed equally to this manuscript	contributed equally to this manuscript	-	-	NO
6047955	30014253	AKR	PLoS52	helped n	helped n	-	-	NO
6047955	30014253	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6047955	30014253	MS	PLoS52	performed the chip assays|performed the if assay	performed the chip assays	Performed the experiments	Investigation	YES
6047955	30014253	MS	PLoS52	performed the chip assays|performed the if assay	performed the if assay	Performed the experiments	Investigation	YES
6047955	30014253	N. Data	PLoS52	sorting and arrangement was done with the	sorting and arrangement was done with the	-	-	NO
6047955	30014253	NAG	PLoS52	provided inputs in interpretation of the data	provided inputs in interpretation of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6047955	30014253	NKK	PLoS52	performed the if assay|helped n	performed the if assay	Performed the experiments	Investigation	YES
6047955	30014253	NKK	PLoS52	performed the if assay|helped n	helped n	-	-	NO
6047955	30014253	RN	PLoS52	conceived and designed the experiments|performed the chip assays|performed the if assay|wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6047955	30014253	RN	PLoS52	conceived and designed the experiments|performed the chip assays|performed the if assay|wrote the manuscript	performed the chip assays	Performed the experiments	Investigation	YES
6047955	30014253	RN	PLoS52	conceived and designed the experiments|performed the chip assays|performed the if assay|wrote the manuscript	performed the if assay	Performed the experiments	Investigation	YES
6047955	30014253	RN	PLoS52	conceived and designed the experiments|performed the chip assays|performed the if assay|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6047955	30014253	RP	PLoS52	conceived and designed the experiments|provided inputs in interpretation of the data|wrote the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6047955	30014253	RP	PLoS52	conceived and designed the experiments|provided inputs in interpretation of the data|wrote the manuscript	provided inputs in interpretation of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6047955	30014253	RP	PLoS52	conceived and designed the experiments|provided inputs in interpretation of the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6047955	30014253	SS	PLoS52	provided inputs in interpretation of the data	provided inputs in interpretation of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6047955	30014253	The authors	PLoS52	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
4418757	25938472	HM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418757	25938472	HN	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418757	25938472	HS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418757	25938472	JI	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418757	25938472	JI	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418757	25938472	KF	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418757	25938472	KS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418757	25938472	MS	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418757	25938472	NF	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418757	25938472	NF	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418757	25938472	SN	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418757	25938472	T. Inoue	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418757	25938472	T. Inoue	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418757	25938472	T. Inoue	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418757	25938472	T. Itoh	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418757	25938472	TB	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418757	25938472	TU	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418757	25938472	TW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418757	25938472	YM	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2031918	17971848	AY	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2031918	17971848	AY	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2031918	17971848	AY	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2031918	17971848	AY	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2031918	17971848	MV	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2031918	17971848	MV	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2031918	17971848	MV	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2031918	17971848	TS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2031918	17971848	TS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2031918	17971848	TS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2031918	17971848	TS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2031918	17971848	TS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5838013	29545814	ES	2	helped to collect samples|performed the experiment	helped to collect samples	Performed the experiments	Investigation	YES
5838013	29545814	ES	2	helped to collect samples|performed the experiment	performed the experiment	Performed the experiments	Investigation	YES
5838013	29545814	Q-FG	2	provided useful suggestions on the manuscript	provided useful suggestions on the manuscript	-	-	NO
5838013	29545814	Y-XQ	2	conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5838013	29545814	Y-YZ	2	conceived the study|analyzed the data and wrote the manuscript|performed the experiment	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5838013	29545814	Y-YZ	2	conceived the study|analyzed the data and wrote the manuscript|performed the experiment	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5838013	29545814	Y-YZ	2	conceived the study|analyzed the data and wrote the manuscript|performed the experiment	performed the experiment	Performed the experiments	Investigation	YES
5838013	29545814	Z-PY	2	helped to collect samples|provided useful suggestions on the manuscript	helped to collect samples	Performed the experiments	Investigation	YES
5838013	29545814	Z-PY	2	helped to collect samples|provided useful suggestions on the manuscript	provided useful suggestions on the manuscript	-	-	NO
5838013	29545814	Z-SW	2	conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
6295792	30445540	D.M.	2	analyzed data and wrote the paper	analyzed data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6295792	30445540	L.R.S.	2	conceived and supervised the project, analyzed data, and wrote the paper	conceived and supervised the project, analyzed data, and wrote the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Supervision|Writing - Original Draft	YES
6295792	30445540	M.M.	2	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
4503967	26150154	JAE	2	study design|manuscript writing|contributed reagents, materials and analysis tools	study design	Conceived and designed the experiments	Methodology	YES
4503967	26150154	JAE	2	study design|manuscript writing|contributed reagents, materials and analysis tools	manuscript writing	Wrote the paper	Writing - Original Draft	YES
4503967	26150154	JAE	2	study design|manuscript writing|contributed reagents, materials and analysis tools	contributed reagents, materials and analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4503967	26150154	NIB	2	study design|manuscript writing	study design	Conceived and designed the experiments	Methodology	YES
4503967	26150154	NIB	2	study design|manuscript writing	manuscript writing	Wrote the paper	Writing - Original Draft	YES
4503967	26150154	SS	2	study design|experiments performing, data analysis and interpretation|manuscript writing	study design	Conceived and designed the experiments	Methodology	YES
4503967	26150154	SS	2	study design|experiments performing, data analysis and interpretation|manuscript writing	experiments performing, data analysis and interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4503967	26150154	SS	2	study design|experiments performing, data analysis and interpretation|manuscript writing	manuscript writing	Wrote the paper	Writing - Original Draft	YES
4503967	26150154	TET	2	study design|experiments performing, data analysis and interpretation|manuscript writing|contributed reagents, materials and analysis tools	study design	Conceived and designed the experiments	Methodology	YES
4503967	26150154	TET	2	study design|experiments performing, data analysis and interpretation|manuscript writing|contributed reagents, materials and analysis tools	experiments performing, data analysis and interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4503967	26150154	TET	2	study design|experiments performing, data analysis and interpretation|manuscript writing|contributed reagents, materials and analysis tools	manuscript writing	Wrote the paper	Writing - Original Draft	YES
4503967	26150154	TET	2	study design|experiments performing, data analysis and interpretation|manuscript writing|contributed reagents, materials and analysis tools	contributed reagents, materials and analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5698624	29109225	A.H.	2	wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
5698624	29109225	I.T.-B.	2	wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
5698624	29109225	T.S.	2	designed the study and carried out the experiments|wrote the article	designed the study and carried out the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5698624	29109225	T.S.	2	designed the study and carried out the experiments|wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
5698624	29109225	Y.S.	2	designed the study and carried out the experiments|wrote the article	designed the study and carried out the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5698624	29109225	Y.S.	2	designed the study and carried out the experiments|wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
5516335	28729905	AN	2	supervised the interpretation of the results and writing of the reports	supervised the interpretation of the results and writing of the reports	Analyzed the data|Wrote the paper	Formal analysis|Supervision	YES
5516335	28729905	NN	2	helped with the statistical analysis and completed the manuscript for publication	helped with the statistical analysis and completed the manuscript for publication	Analyzed the data	Formal analysis	YES
5516335	28729905	SU	2	helped with acquiring data and advised the study methodology	helped with acquiring data and advised the study methodology	Performed the experiments	Investigation|Methodology	YES
5516335	28729905	TH	2	designed the study protocols, acquired the data, and performed the statistical analysis	designed the study protocols, acquired the data, and performed the statistical analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5516335	28729905	TS	2	supervised the interpretation of the results and writing of the reports	supervised the interpretation of the results and writing of the reports	Analyzed the data|Wrote the paper	Formal analysis|Supervision	YES
5516335	28729905	TU	2	supervised the interpretation of the results and writing of the reports	supervised the interpretation of the results and writing of the reports	Analyzed the data|Wrote the paper	Formal analysis|Supervision	YES
5516335	28729905	YK	2	supervised the interpretation of the results and writing of the reports	supervised the interpretation of the results and writing of the reports	Analyzed the data|Wrote the paper	Formal analysis|Supervision	YES
5516335	28729905	YO	2	helped with acquiring data and advised the study methodology	helped with acquiring data and advised the study methodology	Performed the experiments	Investigation|Methodology	YES
3779447	23616286	AA	2	prepared aav	prepared aav	-	-	NO
3779447	23616286	AH	2	performed experiments and acquisition, analysis and interpretation of data	performed experiments and acquisition, analysis and interpretation of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3779447	23616286	ATH	2	performed aav-mediated gene transfer|analysed immunohistochemical data|performed statistical analyses	performed aav-mediated gene transfer	Performed the experiments	Investigation	YES
3779447	23616286	ATH	2	performed aav-mediated gene transfer|analysed immunohistochemical data|performed statistical analyses	analysed immunohistochemical data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3779447	23616286	ATH	2	performed aav-mediated gene transfer|analysed immunohistochemical data|performed statistical analyses	performed statistical analyses	Analyzed the data	Formal analysis	YES
3779447	23616286	CR	2	performed statistical analyses	performed statistical analyses	Analyzed the data	Formal analysis	YES
3779447	23616286	ED	2	performed immunohistochemical staining, macrophage isolation, and qrt pcr	performed immunohistochemical staining, macrophage isolation, and qrt pcr	Performed the experiments	Investigation	YES
3779447	23616286	JS	2	performed ligations|performed aav-mediated gene transfer	performed ligations	Performed the experiments	Investigation	YES
3779447	23616286	JS	2	performed ligations|performed aav-mediated gene transfer	performed aav-mediated gene transfer	Performed the experiments	Investigation	YES
3779447	23616286	KA	2	prepared aav	prepared aav	-	-	NO
3779447	23616286	LV	2	performed experiments and acquisition, analysis and interpretation of data|performed immunohistochemical staining, macrophage isolation, and qrt pcr	performed experiments and acquisition, analysis and interpretation of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3779447	23616286	LV	2	performed experiments and acquisition, analysis and interpretation of data|performed immunohistochemical staining, macrophage isolation, and qrt pcr	performed immunohistochemical staining, macrophage isolation, and qrt pcr	Performed the experiments	Investigation	YES
3779447	23616286	MDP	2	provided the lv technologies and edited the manuscript	provided the lv technologies and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
3779447	23616286	MM	2	conducted scientific direction and wrote the manuscript	conducted scientific direction and wrote the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
3779447	23616286	SC	2	performed immunohistochemical staining, macrophage isolation, and qrt pcr	performed immunohistochemical staining, macrophage isolation, and qrt pcr	Performed the experiments	Investigation	YES
3779447	23616286	YT	2	performed ligations|performed immunohistochemical staining, macrophage isolation, and qrt pcr	performed ligations	Performed the experiments	Investigation	YES
3779447	23616286	YT	2	performed ligations|performed immunohistochemical staining, macrophage isolation, and qrt pcr	performed immunohistochemical staining, macrophage isolation, and qrt pcr	Performed the experiments	Investigation	YES
5831847	29490630	All authors	2	were involved in critically reading and editing the manuscript, and gave the final approval of the version to be published|agreed to be accountable for all aspects of the work	were involved in critically reading and editing the manuscript, and gave the final approval of the version to be published	Wrote the paper	Writing - Review & Editing	YES
5831847	29490630	All authors	2	were involved in critically reading and editing the manuscript, and gave the final approval of the version to be published|agreed to be accountable for all aspects of the work	agreed to be accountable for all aspects of the work	-	-	NO
5831847	29490630	HL	2	developed the atacseqqc package|designed the atacseqqc package and helped with debugging and documentation|analyzed the public datasets and generated all the figures and tables|interpreted the data|drafted the manuscript|contributed equally to this work	developed the atacseqqc package	-	-	NO
5831847	29490630	HL	2	developed the atacseqqc package|designed the atacseqqc package and helped with debugging and documentation|analyzed the public datasets and generated all the figures and tables|interpreted the data|drafted the manuscript|contributed equally to this work	designed the atacseqqc package and helped with debugging and documentation	Conceived and designed the experiments	-	YES
5831847	29490630	HL	2	developed the atacseqqc package|designed the atacseqqc package and helped with debugging and documentation|analyzed the public datasets and generated all the figures and tables|interpreted the data|drafted the manuscript|contributed equally to this work	analyzed the public datasets and generated all the figures and tables	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
5831847	29490630	HL	2	developed the atacseqqc package|designed the atacseqqc package and helped with debugging and documentation|analyzed the public datasets and generated all the figures and tables|interpreted the data|drafted the manuscript|contributed equally to this work	interpreted the data	Analyzed the data	Formal analysis	YES
5831847	29490630	HL	2	developed the atacseqqc package|designed the atacseqqc package and helped with debugging and documentation|analyzed the public datasets and generated all the figures and tables|interpreted the data|drafted the manuscript|contributed equally to this work	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5831847	29490630	HL	2	developed the atacseqqc package|designed the atacseqqc package and helped with debugging and documentation|analyzed the public datasets and generated all the figures and tables|interpreted the data|drafted the manuscript|contributed equally to this work	contributed equally to this work	-	-	NO
5831847	29490630	JO	2	developed the atacseqqc package|designed the atacseqqc package and helped with debugging and documentation|interpreted the data|contributed equally to this work	developed the atacseqqc package	-	-	NO
5831847	29490630	JO	2	developed the atacseqqc package|designed the atacseqqc package and helped with debugging and documentation|interpreted the data|contributed equally to this work	designed the atacseqqc package and helped with debugging and documentation	Conceived and designed the experiments	-	YES
5831847	29490630	JO	2	developed the atacseqqc package|designed the atacseqqc package and helped with debugging and documentation|interpreted the data|contributed equally to this work	interpreted the data	Analyzed the data	Formal analysis	YES
5831847	29490630	JO	2	developed the atacseqqc package|designed the atacseqqc package and helped with debugging and documentation|interpreted the data|contributed equally to this work	contributed equally to this work	-	-	NO
5831847	29490630	JY	2	designed the atacseqqc package and helped with debugging and documentation|interpreted the data	designed the atacseqqc package and helped with debugging and documentation	Conceived and designed the experiments	-	YES
5831847	29490630	JY	2	designed the atacseqqc package and helped with debugging and documentation|interpreted the data	interpreted the data	Analyzed the data	Formal analysis	YES
5831847	29490630	LHC	2	generated the initial datasets for designing and testing the package|interpreted the data	generated the initial datasets for designing and testing the package	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5831847	29490630	LHC	2	generated the initial datasets for designing and testing the package|interpreted the data	interpreted the data	Analyzed the data	Formal analysis	YES
5831847	29490630	LJZ	2	conceived the idea|designed the atacseqqc package and helped with debugging and documentation|interpreted the data|drafted the manuscript	conceived the idea	Conceived and designed the experiments	Conceptualization	YES
5831847	29490630	LJZ	2	conceived the idea|designed the atacseqqc package and helped with debugging and documentation|interpreted the data|drafted the manuscript	designed the atacseqqc package and helped with debugging and documentation	Conceived and designed the experiments	-	YES
5831847	29490630	LJZ	2	conceived the idea|designed the atacseqqc package and helped with debugging and documentation|interpreted the data|drafted the manuscript	interpreted the data	Analyzed the data	Formal analysis	YES
5831847	29490630	LJZ	2	conceived the idea|designed the atacseqqc package and helped with debugging and documentation|interpreted the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5831847	29490630	MAK	2	generated the initial datasets for designing and testing the package|interpreted the data	generated the initial datasets for designing and testing the package	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5831847	29490630	MAK	2	generated the initial datasets for designing and testing the package|interpreted the data	interpreted the data	Analyzed the data	Formal analysis	YES
5831847	29490630	NDL	2	generated the initial datasets for designing and testing the package|interpreted the data	generated the initial datasets for designing and testing the package	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5831847	29490630	NDL	2	generated the initial datasets for designing and testing the package|interpreted the data	interpreted the data	Analyzed the data	Formal analysis	YES
6270884	24705562	M. V. Putz	2	set up the bondonic phase-transition algorithm, and performed the input, parabolic energetic and critical regime calculations for pristine to defective nanolattices	set up the bondonic phase-transition algorithm, and performed the input, parabolic energetic and critical regime calculations for pristine to defective nanolattices	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Methodology|Software	YES
6270884	24705562	O. Ori	2	performed the topological calculation and supervised their further implementation	performed the topological calculation and supervised their further implementation	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Supervision	YES
3913190	24523649	All the authors	2	contributed to the conception and design of the study	contributed to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3913190	24523649	C. A. Malheiros	2	provided the idea for the study, established the hypothesis, and wrote the original proposal|with input from all coauthors	provided the idea for the study, established the hypothesis, and wrote the original proposal	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
3913190	24523649	C. A. Malheiros	2	provided the idea for the study, established the hypothesis, and wrote the original proposal|with input from all coauthors	with input from all coauthors	-	-	NO
3913190	24523649	E. J. Ilias	2	provided the idea for the study, established the hypothesis, and wrote the original proposal|with input from all coauthors	provided the idea for the study, established the hypothesis, and wrote the original proposal	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
3913190	24523649	E. J. Ilias	2	provided the idea for the study, established the hypothesis, and wrote the original proposal|with input from all coauthors	with input from all coauthors	-	-	NO
3913190	24523649	F. C. Martins	2	were involved in surgical procedures, and critically revised the paper	were involved in surgical procedures, and critically revised the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
3913190	24523649	Freitas Junior	2	provided the idea for the study, established the hypothesis, and wrote the original proposal|with input from all coauthors	provided the idea for the study, established the hypothesis, and wrote the original proposal	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
3913190	24523649	Freitas Junior	2	provided the idea for the study, established the hypothesis, and wrote the original proposal|with input from all coauthors	with input from all coauthors	-	-	NO
3913190	24523649	M. I. Ali	2	were involved in surgical procedures, and critically revised the paper	were involved in surgical procedures, and critically revised the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
3913190	24523649	O. Castro	2	were involved in surgical procedures, and critically revised the paper	were involved in surgical procedures, and critically revised the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
3913190	24523649	P. Carrara	2	were involved in surgical procedures, and critically revised the paper	were involved in surgical procedures, and critically revised the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
3913190	24523649	P. G. Porto	2	were involved in surgical procedures, and critically revised the paper	were involved in surgical procedures, and critically revised the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
3913190	24523649	P. Kassab	2	were involved in surgical procedures, and critically revised the paper	were involved in surgical procedures, and critically revised the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
3913190	24523649	R. Cordts	2	were involved in surgical procedures, and critically revised the paper	were involved in surgical procedures, and critically revised the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
2031919	17957252	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2031919	17957252	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2031919	17957252	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2031919	17957252	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2031919	17957252	IA	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2031919	17957252	IA	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2031919	17957252	LL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2031919	17957252	LL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2031919	17957252	LL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2031919	17957252	MS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2031919	17957252	MS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2031919	17957252	MS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2031919	17957252	PS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2031919	17957252	PS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2031919	17957252	SG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2031919	17957252	SG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
2031919	17957252	SG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
6049845	30019247	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6049845	30019247	JM	PLoS52	analyzed the data and drew the figures	analyzed the data and drew the figures	Analyzed the data	Formal analysis|Visualization	YES
6049845	30019247	MC	PLoS52	performed the experiment and wrote the paper	performed the experiment and wrote the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6049845	30019247	XZ	PLoS52	performed the experiment and analyzed the data	performed the experiment and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6049845	30019247	ZCW	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
6049845	30019247	ZWW	PLoS52	conceived the idea and wrote the paper	conceived the idea and wrote the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4503968	26150155	AMS	2	experimental work, study execution, data interpretation and analysis, manuscript writing	experimental work, study execution, data interpretation and analysis, manuscript writing	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4503968	26150155	MPT	2	study design conception and planning, results discussing and supervision	study design conception and planning, results discussing and supervision	Conceived and designed the experiments	Conceptualization|Methodology|Supervision	YES
4503968	26150155	OA	2	contribution to data collection, technical assistance, data interpretation and analysis	contribution to data collection, technical assistance, data interpretation and analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
4503968	26150155	RL	2	study design conception and planning, results discussing and supervision	study design conception and planning, results discussing and supervision	Conceived and designed the experiments	Conceptualization|Methodology|Supervision	YES
4503968	26150155	SB	2	experimental work, study execution, data interpretation and analysis, manuscript writing	experimental work, study execution, data interpretation and analysis, manuscript writing	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4418758	25938232	APL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418758	25938232	APL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418758	25938232	APL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418758	25938232	ASG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418758	25938232	CMAL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418758	25938232	CMAL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418758	25938232	CMAL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418758	25938232	CMAL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418758	25938232	JJF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418758	25938232	JJF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418758	25938232	JJF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418758	25938232	JJF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418758	25938232	LML	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418758	25938232	LML	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418758	25938232	LML	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418758	25938232	LRG	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418758	25938232	MCW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418758	25938232	MCW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418758	25938232	MCW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418758	25938232	MCW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418758	25938232	PMF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418758	25938232	PMF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418758	25938232	PMF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418758	25938232	PMF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418758	25938232	SB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418758	25938232	SB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418758	25938232	SB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418758	25938232	SB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418758	25938232	TCAJ	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418758	25938232	WMD	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418758	25938232	WMD	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4201327	25275953	H.S.	2	contributed equally to this work	contributed equally to this work	-	-	NO
4201327	25275953	SS	2	contributed equally to this work	contributed equally to this work	-	-	NO
4201327	25275953	W.H.	2	contributed equally to this work	contributed equally to this work	-	-	NO
5838088	29545815	AT	PLoS52	designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
5838088	29545815	GB	PLoS52	contributed to analytical procedures	contributed to analytical procedures	Performed the experiments	Investigation	YES
5838088	29545815	MC	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5838088	29545815	MW	PLoS52	designed the research|analyzed the data and wrote the article	designed the research	Conceived and designed the experiments	Methodology	YES
5838088	29545815	MW	PLoS52	designed the research|analyzed the data and wrote the article	analyzed the data and wrote the article	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5838088	29545815	RS	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5838088	29545815	RW	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5838088	29545815	WK	PLoS52	contributed to analytical procedures	contributed to analytical procedures	Performed the experiments	Investigation	YES
3779448	23653322	AI	2	provided intellectual input into the cellular and animal studies	provided intellectual input into the cellular and animal studies	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
3779448	23653322	AS	2	provided critical input into the overall research direction|wrote the paper with input from all co-authors who read, edited and approved the final copy of the manuscript	provided critical input into the overall research direction	-	-	NO
3779448	23653322	AS	2	provided critical input into the overall research direction|wrote the paper with input from all co-authors who read, edited and approved the final copy of the manuscript	wrote the paper with input from all co-authors who read, edited and approved the final copy of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3779448	23653322	ASP	2	designed and performed in vitro and in vivo experiments|designed and performed animal studies|provided critical input into the overall research direction|wrote the paper with input from all co-authors who read, edited and approved the final copy of the manuscript	designed and performed in vitro and in vivo experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3779448	23653322	ASP	2	designed and performed in vitro and in vivo experiments|designed and performed animal studies|provided critical input into the overall research direction|wrote the paper with input from all co-authors who read, edited and approved the final copy of the manuscript	designed and performed animal studies	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3779448	23653322	ASP	2	designed and performed in vitro and in vivo experiments|designed and performed animal studies|provided critical input into the overall research direction|wrote the paper with input from all co-authors who read, edited and approved the final copy of the manuscript	provided critical input into the overall research direction	-	-	NO
3779448	23653322	ASP	2	designed and performed in vitro and in vivo experiments|designed and performed animal studies|provided critical input into the overall research direction|wrote the paper with input from all co-authors who read, edited and approved the final copy of the manuscript	wrote the paper with input from all co-authors who read, edited and approved the final copy of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3779448	23653322	BM	2	provided critical input into the overall research direction|wrote the paper with input from all co-authors who read, edited and approved the final copy of the manuscript	provided critical input into the overall research direction	-	-	NO
3779448	23653322	BM	2	provided critical input into the overall research direction|wrote the paper with input from all co-authors who read, edited and approved the final copy of the manuscript	wrote the paper with input from all co-authors who read, edited and approved the final copy of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3779448	23653322	DB	2	designed and performed in vitro and in vivo experiments|designed and performed animal studies	designed and performed in vitro and in vivo experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3779448	23653322	DB	2	designed and performed in vitro and in vivo experiments|designed and performed animal studies	designed and performed animal studies	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3779448	23653322	JH	2	designed and performed in vitro and in vivo experiments	designed and performed in vitro and in vivo experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3779448	23653322	KM	2	designed and performed in vitro and in vivo experiments	designed and performed in vitro and in vivo experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3779448	23653322	LGG	2	provided intellectual input into the cellular and animal studies	provided intellectual input into the cellular and animal studies	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
3779448	23653322	LN	2	provided intellectual input into the cellular and animal studies	provided intellectual input into the cellular and animal studies	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
3779448	23653322	MDP	2	designed and supervised tie2 knockdown and tie2-bmdm delivery studies|provided critical input into the overall research direction|wrote the paper with input from all co-authors who read, edited and approved the final copy of the manuscript	designed and supervised tie2 knockdown and tie2-bmdm delivery studies	Conceived and designed the experiments	Methodology|Supervision	YES
3779448	23653322	MDP	2	designed and supervised tie2 knockdown and tie2-bmdm delivery studies|provided critical input into the overall research direction|wrote the paper with input from all co-authors who read, edited and approved the final copy of the manuscript	provided critical input into the overall research direction	-	-	NO
3779448	23653322	MDP	2	designed and supervised tie2 knockdown and tie2-bmdm delivery studies|provided critical input into the overall research direction|wrote the paper with input from all co-authors who read, edited and approved the final copy of the manuscript	wrote the paper with input from all co-authors who read, edited and approved the final copy of the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3779448	23653322	MW	2	provided intellectual input into the cellular and animal studies	provided intellectual input into the cellular and animal studies	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
3779448	23653322	OTL	2	designed and performed in vitro and in vivo experiments	designed and performed in vitro and in vivo experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3779448	23653322	PS	2	provided intellectual input into the cellular and animal studies	provided intellectual input into the cellular and animal studies	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
3779448	23653322	RQA	2	designed and performed in vitro and in vivo experiments	designed and performed in vitro and in vivo experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3779448	23653322	RS	2	provided intellectual input into the cellular and animal studies	provided intellectual input into the cellular and animal studies	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
3779448	23653322	SE	2	taught, supervised and provided expertise with the murine model of hli	taught, supervised and provided expertise with the murine model of hli	Performed the experiments	Methodology|Supervision	YES
3779448	23653322	SN	2	designed and performed in vitro and in vivo experiments|designed and performed animal studies	designed and performed in vitro and in vivo experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3779448	23653322	SN	2	designed and performed in vitro and in vivo experiments|designed and performed animal studies	designed and performed animal studies	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3779448	23653322	SPG	2	designed and performed animal studies	designed and performed animal studies	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5516371	28729904	ACFT	2	participated in manuscript writing and review	participated in manuscript writing and review	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5516371	28729904	AMGTC	2	performed all data collection	performed all data collection	Performed the experiments	Investigation	YES
5516371	28729904	BSMO	2	participated in manuscript writing and review	participated in manuscript writing and review	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5516371	28729904	MES	2	participated in manuscript writing and review	participated in manuscript writing and review	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5516371	28729904	MMFA	2	participated in manuscript writing and review	participated in manuscript writing and review	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5516371	28729904	RWG	2	performed all data collection	performed all data collection	Performed the experiments	Investigation	YES
5516371	28729904	SFJL	2	participated in manuscript writing and review	participated in manuscript writing and review	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5516371	28729904	TF	2	conceived the study, performed data analysis, and participated in manuscript writing and review	conceived the study, performed data analysis, and participated in manuscript writing and review	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5831853	29490606	LOD	1	Conception and design of the study|Acquisition of data for the study|Analysis of data for the work|Interpretation of data for the work|Manuscript revision and approval	Conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5831853	29490606	LOD	1	Conception and design of the study|Acquisition of data for the study|Analysis of data for the work|Interpretation of data for the work|Manuscript revision and approval	Acquisition of data for the study	Performed the experiments	Investigation	YES
5831853	29490606	LOD	1	Conception and design of the study|Acquisition of data for the study|Analysis of data for the work|Interpretation of data for the work|Manuscript revision and approval	Analysis of data for the work	Analyzed the data	Formal analysis	YES
5831853	29490606	LOD	1	Conception and design of the study|Acquisition of data for the study|Analysis of data for the work|Interpretation of data for the work|Manuscript revision and approval	Interpretation of data for the work	Analyzed the data	Formal analysis	YES
5831853	29490606	LOD	1	Conception and design of the study|Acquisition of data for the study|Analysis of data for the work|Interpretation of data for the work|Manuscript revision and approval	Manuscript revision and approval	Wrote the paper	Writing - Review & Editing	YES
5831853	29490606	MOD	1	Analysis of data for the work|Manuscript revision and approval	Analysis of data for the work	Analyzed the data	Formal analysis	YES
5831853	29490606	MOD	1	Analysis of data for the work|Manuscript revision and approval	Manuscript revision and approval	Wrote the paper	Writing - Review & Editing	YES
5831853	29490606	TC	1	Analysis of data for the work|Interpretation of data for the work|Manuscript revision and approval	Analysis of data for the work	Analyzed the data	Formal analysis	YES
5831853	29490606	TC	1	Analysis of data for the work|Interpretation of data for the work|Manuscript revision and approval	Interpretation of data for the work	Analyzed the data	Formal analysis	YES
5831853	29490606	TC	1	Analysis of data for the work|Interpretation of data for the work|Manuscript revision and approval	Manuscript revision and approval	Wrote the paper	Writing - Review & Editing	YES
6270886	24727413	Baochang Cai	2	authenticated the plant materials, and supervised the whole research project	authenticated the plant materials, and supervised the whole research project	Performed the experiments	Investigation|Supervision	YES
6270886	24727413	Dongyue Wang	2	helped in the hplc analysis	helped in the hplc analysis	Performed the experiments	Investigation	YES
6270886	24727413	Hao Cai	2	helped in the hplc analysis	helped in the hplc analysis	Performed the experiments	Investigation	YES
6270886	24727413	MTAF	2	prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
6270886	24727413	Pei Peng	2	contributed to the pharmacological test	contributed to the pharmacological test	-	-	NO
6270886	24727413	Yange Qu	2	contributed to the pharmacological test	contributed to the pharmacological test	-	-	NO
6270886	24727413	Ying Gao	2	contributed to the pharmacological test	contributed to the pharmacological test	-	-	NO
6270886	24727413	Zhipeng Chen	2	was responsible for the pharmacokinetic study	was responsible for the pharmacokinetic study	-	-	NO
2031920	17957262	BL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2031920	17957262	BL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2031920	17957262	BL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2031920	17957262	BL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2031920	17957262	DN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2031920	17957262	DN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2031920	17957262	DN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2031920	17957262	DN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2031920	17957262	EK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2031920	17957262	EK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2031920	17957262	EK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2031920	17957262	EK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2031920	17957262	ES	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2031920	17957262	ES	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2031920	17957262	ES	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2031920	17957262	ES	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2031920	17957262	JB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2031920	17957262	JB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2031920	17957262	JB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2031920	17957262	KB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2031920	17957262	KB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2031920	17957262	KB	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2031920	17957262	KG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2031920	17957262	KG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2031920	17957262	KG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2031920	17957262	KG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2031920	17957262	MA	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2031920	17957262	MA	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2031920	17957262	MS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2031920	17957262	MS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2031920	17957262	MS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2031920	17957262	SO	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2031920	17957262	SO	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2031920	17957262	TH	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2031920	17957262	TH	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6049849	30019301	AKY	PLoS52	performed experiment and analyzed the data	performed experiment and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6049849	30019301	All	PLoS52	data are fully available without restriction	data are fully available without restriction	-	-	NO
6049849	30019301	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6049849	30019301	CW	PLoS52	conceived of the study|wrote the paper	conceived of the study	Conceived and designed the experiments	Conceptualization	YES
6049849	30019301	CW	PLoS52	conceived of the study|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6049849	30019301	JG	PLoS52	performed experiment and analyzed the data	performed experiment and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6049849	30019301	JZ	PLoS52	performed experiment and analyzed the data	performed experiment and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6049849	30019301	KQ	PLoS52	performed experiment and analyzed the data	performed experiment and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6049849	30019301	LC	PLoS52	conceived of the study	conceived of the study	Conceived and designed the experiments	Conceptualization	YES
6049849	30019301	LW	PLoS52	conceived of the study|wrote the paper	conceived of the study	Conceived and designed the experiments	Conceptualization	YES
6049849	30019301	LW	PLoS52	conceived of the study|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6049849	30019301	RRG	PLoS52	performed experiment and analyzed the data	performed experiment and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6049849	30019301	The authors	PLoS52	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
6049849	30019301	XH	PLoS52	conceived of the study|wrote the paper	conceived of the study	Conceived and designed the experiments	Conceptualization	YES
6049849	30019301	XH	PLoS52	conceived of the study|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6049849	30019301	YY	PLoS52	performed experiment and analyzed the data	performed experiment and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6049849	30019301	YZ	PLoS52	performed experiment and analyzed the data	performed experiment and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4503970	26150157	JY	2	research theme definition, methods design, manuscript revision	research theme definition, methods design, manuscript revision	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Writing - Review & Editing	YES
4503970	26150157	WL	2	laboratory experiments, results analysis and interpretation, manuscript writing	laboratory experiments, results analysis and interpretation, manuscript writing	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4418759	25938408	AL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418759	25938408	FB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418759	25938408	FB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418759	25938408	FB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418759	25938408	FB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418759	25938408	FB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418759	25938408	PG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418759	25938408	SY	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418759	25938408	ZS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418759	25938408	ZS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4418759	25938408	ZS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5838469	29545817	DJ	2	designed the experiments|involved in the results discussion, manuscript writing and revising	designed the experiments	Conceived and designed the experiments	Methodology	YES
5838469	29545817	DJ	2	designed the experiments|involved in the results discussion, manuscript writing and revising	involved in the results discussion, manuscript writing and revising	Wrote the paper	Writing - Original Draft	YES
5838469	29545817	JCa	2	involved in the results discussion, manuscript writing and revising	involved in the results discussion, manuscript writing and revising	Wrote the paper	Writing - Original Draft	YES
5838469	29545817	JCh	2	performed the experiments and data analysis	performed the experiments and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5838469	29545817	QZ	2	involved in the results discussion, manuscript writing and revising	involved in the results discussion, manuscript writing and revising	Wrote the paper	Writing - Original Draft	YES
5838469	29545817	TD	2	involved in the results discussion, manuscript writing and revising	involved in the results discussion, manuscript writing and revising	Wrote the paper	Writing - Original Draft	YES
5838469	29545817	WC	2	involved in the results discussion, manuscript writing and revising	involved in the results discussion, manuscript writing and revising	Wrote the paper	Writing - Original Draft	YES
5838469	29545817	XW	2	designed the experiments|involved in the results discussion, manuscript writing and revising	designed the experiments	Conceived and designed the experiments	Methodology	YES
5838469	29545817	XW	2	designed the experiments|involved in the results discussion, manuscript writing and revising	involved in the results discussion, manuscript writing and revising	Wrote the paper	Writing - Original Draft	YES
5838469	29545817	XZ	2	performed the experiments and data analysis	performed the experiments and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5838469	29545817	XlW	2	performed the experiments and data analysis|involved in the results discussion, manuscript writing and revising	performed the experiments and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5838469	29545817	XlW	2	performed the experiments and data analysis|involved in the results discussion, manuscript writing and revising	involved in the results discussion, manuscript writing and revising	Wrote the paper	Writing - Original Draft	YES
3779449	23630012	AM	2	performed experiments with wipi-2 and wipi-1	performed experiments with wipi-2 and wipi-1	Performed the experiments	Investigation	YES
3779449	23630012	All authors	2	discussed the results and commented on the manuscript	discussed the results and commented on the manuscript	-	-	NO
3779449	23630012	BB	2	performed muscle force measurement experiments	performed muscle force measurement experiments	Performed the experiments	Investigation	YES
3779449	23630012	CC	2	lab performed lysosomal enzymes assays	lab performed lysosomal enzymes assays	Performed the experiments	Investigation	YES
3779449	23630012	CP	2	performed em experiments	performed em experiments	Performed the experiments	Investigation	YES
3779449	23630012	FP	2	performed em experiments	performed em experiments	Performed the experiments	Investigation	YES
3779449	23630012	GP	2	designed, performed most of the experimental work and analysed data|wrote the manuscript	designed, performed most of the experimental work and analysed data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
3779449	23630012	GP	2	designed, performed most of the experimental work and analysed data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3779449	23630012	INe	2	designed, performed most of the experimental work and analysed data|wrote the manuscript	designed, performed most of the experimental work and analysed data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
3779449	23630012	INe	2	designed, performed most of the experimental work and analysed data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3779449	23630012	INi	2	shared reagents and expertise	shared reagents and expertise	Contributed reagents/materials/analysis tools	Resources	YES
3779449	23630012	KO	2	line and performed muscle electroporation experiments	line and performed muscle electroporation experiments	Performed the experiments	Investigation	YES
3779449	23630012	MP	2	conceived and directed the study|wrote the manuscript	conceived and directed the study	Conceived and designed the experiments	Conceptualization|Supervision	YES
3779449	23630012	MP	2	conceived and directed the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3779449	23630012	RCR	2	in klg lab performed in vitro pi3p kinase assay	in klg lab performed in vitro pi3p kinase assay	Performed the experiments	Investigation	YES
3779449	23630012	TPC	2	performed experiments with wipi-2 and wipi-1	performed experiments with wipi-2 and wipi-1	Performed the experiments	Investigation	YES
5517801	28729908	KS	2	contributed to writing a draft version of the manuscript	contributed to writing a draft version of the manuscript	Wrote the paper	Writing - Original Draft	YES
5517801	28729908	YT	2	is responsible for writing and adjusting the manuscript	is responsible for writing and adjusting the manuscript	Wrote the paper	Writing - Original Draft	YES
4503971	26150158	AACC	PLoS52	immunohistochemical techniques|morphometric analysis of the inflammatory infiltrate and the area of the antral lamina propria	immunohistochemical techniques	Performed the experiments	Investigation	YES
4503971	26150158	AACC	PLoS52	immunohistochemical techniques|morphometric analysis of the inflammatory infiltrate and the area of the antral lamina propria	morphometric analysis of the inflammatory infiltrate and the area of the antral lamina propria	-	-	NO
4503971	26150158	AETD	PLoS52	inoculation of the animals, necropsy and histopathological techniques	inoculation of the animals, necropsy and histopathological techniques	Performed the experiments	Investigation	YES
4503971	26150158	CMB	PLoS52	inoculation of the animals, necropsy and histopathological techniques	inoculation of the animals, necropsy and histopathological techniques	Performed the experiments	Investigation	YES
4503971	26150158	CagA	PLoS52	translocation and dna sequencing	translocation and dna sequencing	Performed the experiments	Investigation	YES
4503971	26150158	DMMQ	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4503971	26150158	FMSO	PLoS52	immunohistochemical techniques	immunohistochemical techniques	Performed the experiments	Investigation	YES
4503971	26150158	IDA	PLoS52	classification and grading of gastritis by the sydney system and macroscopic analysis of the gastric mucosa	classification and grading of gastritis by the sydney system and macroscopic analysis of the gastric mucosa	-	-	NO
4503971	26150158	LOP	PLoS52	immunohistochemical techniques	immunohistochemical techniques	Performed the experiments	Investigation	YES
4503971	26150158	MFJ	PLoS52	inoculation of the animals, necropsy and histopathological techniques|immunohistochemical techniques|morphometric analysis of the inflammatory infiltrate and the area of the antral lamina propria|wrote the paper	inoculation of the animals, necropsy and histopathological techniques	Performed the experiments	Investigation	YES
4503971	26150158	MFJ	PLoS52	inoculation of the animals, necropsy and histopathological techniques|immunohistochemical techniques|morphometric analysis of the inflammatory infiltrate and the area of the antral lamina propria|wrote the paper	immunohistochemical techniques	Performed the experiments	Investigation	YES
4503971	26150158	MFJ	PLoS52	inoculation of the animals, necropsy and histopathological techniques|immunohistochemical techniques|morphometric analysis of the inflammatory infiltrate and the area of the antral lamina propria|wrote the paper	morphometric analysis of the inflammatory infiltrate and the area of the antral lamina propria	-	-	NO
4503971	26150158	MFJ	PLoS52	inoculation of the animals, necropsy and histopathological techniques|immunohistochemical techniques|morphometric analysis of the inflammatory infiltrate and the area of the antral lamina propria|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4503971	26150158	MVC	PLoS52	inoculation of the animals, necropsy and histopathological techniques|morphometric analysis of the inflammatory infiltrate and the area of the antral lamina propria|wrote the paper	inoculation of the animals, necropsy and histopathological techniques	Performed the experiments	Investigation	YES
4503971	26150158	MVC	PLoS52	inoculation of the animals, necropsy and histopathological techniques|morphometric analysis of the inflammatory infiltrate and the area of the antral lamina propria|wrote the paper	morphometric analysis of the inflammatory infiltrate and the area of the antral lamina propria	-	-	NO
4503971	26150158	MVC	PLoS52	inoculation of the animals, necropsy and histopathological techniques|morphometric analysis of the inflammatory infiltrate and the area of the antral lamina propria|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4503971	26150158	PVTV	PLoS52	classification and grading of gastritis by the sydney system and macroscopic analysis of the gastric mucosa	classification and grading of gastritis by the sydney system and macroscopic analysis of the gastric mucosa	-	-	NO
4503971	26150158	RCB	PLoS52	inoculation of the animals, necropsy and histopathological techniques	inoculation of the animals, necropsy and histopathological techniques	Performed the experiments	Investigation	YES
5831862	29490613	BD	PLoS52	designed and monitored the experiments, and drafted and revised the manuscript	designed and monitored the experiments, and drafted and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
5831862	29490613	CZL	PLoS52	analyzed the data and prepared part of the manuscript	analyzed the data and prepared part of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5831862	29490613	HYY	PLoS52	provided the reagents for experiments and advice on data analysis	provided the reagents for experiments and advice on data analysis	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5831862	29490613	JKW	PLoS52	analyzed rna seq data for target gene prediction	analyzed rna seq data for target gene prediction	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5831862	29490613	XMZ	PLoS52	performed the experiments, analyzed the data, drafted the figures, and prepared the manuscript	performed the experiments, analyzed the data, drafted the figures, and prepared the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Visualization|Writing - Original Draft	YES
5831862	29490613	XZL	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
2031921	17957263	HV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2031921	17957263	HV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2031921	17957263	HV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2031921	17957263	HV	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2031921	17957263	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2031921	17957263	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2031921	17957263	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2031921	17957263	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2031921	17957263	TM	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2031921	17957263	TM	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270888	24858095	Adam McCluskey	2	participated in designing this study	participated in designing this study	Conceived and designed the experiments	Methodology	YES
6270888	24858095	Mohammed Abdel-Hamid	2	participated in designing this study|conducted the molecular modeling experiments	participated in designing this study	Conceived and designed the experiments	Methodology	YES
6270888	24858095	Mohammed Abdel-Hamid	2	participated in designing this study|conducted the molecular modeling experiments	conducted the molecular modeling experiments	Performed the experiments	Investigation|Methodology	YES
4418760	25938567	CB	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4418760	25938567	CB	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418760	25938567	EB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418760	25938567	EB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4418760	25938567	EB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418760	25938567	MES	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4418760	25938567	MES	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418760	25938567	VB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418760	25938567	VB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418760	25938567	VB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418760	25938567	VB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3779450	23681668	DEP	2	provided critical input to the overall research direction	provided critical input to the overall research direction	-	-	NO
3779450	23681668	DJD	2	designed experiments and interpreted data|carried out all the eae experiments with technical|wrote the paper with input from all co-authors	designed experiments and interpreted data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
3779450	23681668	DJD	2	designed experiments and interpreted data|carried out all the eae experiments with technical|wrote the paper with input from all co-authors	carried out all the eae experiments with technical	Performed the experiments	Investigation	YES
3779450	23681668	DJD	2	designed experiments and interpreted data|carried out all the eae experiments with technical|wrote the paper with input from all co-authors	wrote the paper with input from all co-authors	Wrote the paper	Writing - Original Draft	YES
3779450	23681668	OVC	2	assisted with the carried out all the eae experiments with technical	assisted with the carried out all the eae experiments with technical	Performed the experiments	Investigation	YES
3779450	23681668	VS	2	assisted with the carried out all the eae experiments with technical	assisted with the carried out all the eae experiments with technical	Performed the experiments	Investigation	YES
3779450	23681668	WD	2	designed experiments and interpreted data|wrote the paper with input from all co-authors	designed experiments and interpreted data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
3779450	23681668	WD	2	designed experiments and interpreted data|wrote the paper with input from all co-authors	wrote the paper with input from all co-authors	Wrote the paper	Writing - Original Draft	YES
3779450	23681668	XL	2	performed the electron microscopic analysis	performed the electron microscopic analysis	Performed the experiments	Investigation	YES
5517948	28729903	KY	2	supervised the process of the literature search and drafting the manuscript	supervised the process of the literature search and drafting the manuscript	Wrote the paper	Formal analysis|Supervision|Writing - Original Draft	YES
5517948	28729903	TK	2	searched the literature and drafted the manuscript	searched the literature and drafted the manuscript	Wrote the paper	Formal analysis|Writing - Original Draft	YES
5517948	28729903	TN	2	searched the literature and drafted the manuscript	searched the literature and drafted the manuscript	Wrote the paper	Formal analysis|Writing - Original Draft	YES
4503972	26150159	AF	2	experiments performing|results of experiments interpretation	experiments performing	Performed the experiments	Investigation	YES
4503972	26150159	AF	2	experiments performing|results of experiments interpretation	results of experiments interpretation	Analyzed the data	Formal analysis	YES
4503972	26150159	CG	2	research conception and design|results of experiments interpretation	research conception and design	Conceived and designed the experiments	Conceptualization	YES
4503972	26150159	CG	2	research conception and design|results of experiments interpretation	results of experiments interpretation	Analyzed the data	Formal analysis	YES
4503972	26150159	DF	2	research conception and design	research conception and design	Conceived and designed the experiments	Conceptualization	YES
4503972	26150159	EO	2	experiments performing|results of experiments interpretation	experiments performing	Performed the experiments	Investigation	YES
4503972	26150159	EO	2	experiments performing|results of experiments interpretation	results of experiments interpretation	Analyzed the data	Formal analysis	YES
4503972	26150159	LV	2	research conception and design|experiments performing|manuscript drafting	research conception and design	Conceived and designed the experiments	Conceptualization	YES
4503972	26150159	LV	2	research conception and design|experiments performing|manuscript drafting	experiments performing	Performed the experiments	Investigation	YES
4503972	26150159	LV	2	research conception and design|experiments performing|manuscript drafting	manuscript drafting	Wrote the paper	Writing - Original Draft	YES
4503972	26150159	RA	2	research conception and design|manuscript drafting|manuscript critical revision	research conception and design	Conceived and designed the experiments	Conceptualization	YES
4503972	26150159	RA	2	research conception and design|manuscript drafting|manuscript critical revision	manuscript drafting	Wrote the paper	Writing - Original Draft	YES
4503972	26150159	RA	2	research conception and design|manuscript drafting|manuscript critical revision	manuscript critical revision	Wrote the paper	Writing - Review & Editing	YES
4503972	26150159	VF	2	research conception and design|manuscript critical revision	research conception and design	Conceived and designed the experiments	Conceptualization	YES
4503972	26150159	VF	2	research conception and design|manuscript critical revision	manuscript critical revision	Wrote the paper	Writing - Review & Editing	YES
4664790	26665149	Baoguo Sun	2	contributed equally to this work	contributed equally to this work	-	-	NO
4664790	26665149	Yan Chen	2	contributed equally to this work	contributed equally to this work	-	-	NO
2031922	17957265	DV	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2031922	17957265	DV	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2031922	17957265	DV	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2031922	17957265	IG	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2031922	17957265	IG	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
2031922	17957265	PM	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5838922	29545818	AW-T	7	Planned and designed the research; AW-T, MT, VC;, and|Analyzed the data|Interpreted the data and wrote the manuscript	Planned and designed the research; AW-T, MT, VC;, and	Conceived and designed the experiments	Conceptualization|Methodology	YES
5838922	29545818	AW-T	7	Planned and designed the research; AW-T, MT, VC;, and|Analyzed the data|Interpreted the data and wrote the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
5838922	29545818	AW-T	7	Planned and designed the research; AW-T, MT, VC;, and|Analyzed the data|Interpreted the data and wrote the manuscript	Interpreted the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5838922	29545818	DS	7	Analyzed the data|Interpreted the data and wrote the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
5838922	29545818	DS	7	Analyzed the data|Interpreted the data and wrote the manuscript	Interpreted the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5838922	29545818	EH	7	Interpreted the data and wrote the manuscript	Interpreted the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5838922	29545818	MT	7	Planned and designed the research; AW-T, MT, VC;, and|Analyzed the data|Interpreted the data and wrote the manuscript	Planned and designed the research; AW-T, MT, VC;, and	Conceived and designed the experiments	Conceptualization|Methodology	YES
5838922	29545818	MT	7	Planned and designed the research; AW-T, MT, VC;, and|Analyzed the data|Interpreted the data and wrote the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
5838922	29545818	MT	7	Planned and designed the research; AW-T, MT, VC;, and|Analyzed the data|Interpreted the data and wrote the manuscript	Interpreted the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5838922	29545818	OT	7	Conducted the laboratory work	Conducted the laboratory work	Performed the experiments	Investigation	YES
6049852	30019324	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6049852	30019324	BJL	2	carried out the part of the mnp experiment	carried out the part of the mnp experiment	Performed the experiments	Investigation	YES
6049852	30019324	RJ	2	conceived of the study, and participated in its design and helped to revise the manuscript	conceived of the study, and participated in its design and helped to revise the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
6049852	30019324	RS	2	participated in part of the work and wrote the paper|contributed equally to this work	participated in part of the work and wrote the paper	Wrote the paper	Writing - Original Draft	YES
6049852	30019324	RS	2	participated in part of the work and wrote the paper|contributed equally to this work	contributed equally to this work	-	-	NO
6049852	30019324	ZHD	2	performed the experiments and wrote the paper|contributed equally to this work	performed the experiments and wrote the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6049852	30019324	ZHD	2	performed the experiments and wrote the paper|contributed equally to this work	contributed equally to this work	-	-	NO
5833046	29499643	CA	2	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5833046	29499643	DVS	2	performed the clinical assessment of the participants and were involved in the interpretation of data	performed the clinical assessment of the participants and were involved in the interpretation of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5833046	29499643	ECO	2	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5833046	29499643	LH	2	evaluated the protein expressions	evaluated the protein expressions	Performed the experiments	Investigation	YES
5833046	29499643	MUB	2	performed the clinical assessment of the participants and were involved in the interpretation of data	performed the clinical assessment of the participants and were involved in the interpretation of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5833046	29499643	PA	2	performed the bioinformatic analysis	performed the bioinformatic analysis	Performed the experiments	Formal analysis|Investigation	YES
5833046	29499643	XH	2	conceived and designed the study|performed the bioinformatic analysis|performed the for quantitative rt-pcr experiments, and wrote the manuscript|evaluated the protein expressions	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5833046	29499643	XH	2	conceived and designed the study|performed the bioinformatic analysis|performed the for quantitative rt-pcr experiments, and wrote the manuscript|evaluated the protein expressions	performed the bioinformatic analysis	Performed the experiments	Formal analysis|Investigation	YES
5833046	29499643	XH	2	conceived and designed the study|performed the bioinformatic analysis|performed the for quantitative rt-pcr experiments, and wrote the manuscript|evaluated the protein expressions	performed the for quantitative rt-pcr experiments, and wrote the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5833046	29499643	XH	2	conceived and designed the study|performed the bioinformatic analysis|performed the for quantitative rt-pcr experiments, and wrote the manuscript|evaluated the protein expressions	evaluated the protein expressions	Performed the experiments	Investigation	YES
6270890	24662083	AH	2	supervised the study and provided financing	supervised the study and provided financing	-	Supervision	YES
6270890	24662083	BabA	2	established the baba interaction assays	established the baba interaction assays	Performed the experiments	Investigation	YES
6270890	24662083	TB	2	established the baba interaction assays	established the baba interaction assays	Performed the experiments	Investigation	YES
4418761	25938608	ADF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418761	25938608	ADF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418761	25938608	ADF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418761	25938608	ADF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418761	25938608	HG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418761	25938608	HG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4418761	25938608	HG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418761	25938608	SC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418761	25938608	SC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4418761	25938608	SC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4503973	26150160	all authors	2	contributed equally	contributed equally	-	-	NO
5518126	28729907	KI	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5518126	28729907	MK	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5518126	28729907	NN	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5518126	28729907	SN	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
3779451	23703906	ANM	2	performed seahorse experiments|prepared manuscript|designed experiments and supervised work	performed seahorse experiments	Performed the experiments	Investigation	YES
3779451	23703906	ANM	2	performed seahorse experiments|prepared manuscript|designed experiments and supervised work	prepared manuscript	Wrote the paper	Writing - Original Draft	YES
3779451	23703906	ANM	2	performed seahorse experiments|prepared manuscript|designed experiments and supervised work	designed experiments and supervised work	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Supervision	YES
3779451	23703906	ASD	2	performed seahorse experiments	performed seahorse experiments	Performed the experiments	Investigation	YES
3779451	23703906	ATP	2	redox measurements	redox measurements	Performed the experiments	Investigation	YES
3779451	23703906	AYA	2	prepared manuscript	prepared manuscript	Wrote the paper	Writing - Original Draft	YES
3779451	23703906	All authors	2	critically reviewed the manuscript	critically reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
3779451	23703906	BGN	2	prepared manuscript|designed experiments and supervised work	prepared manuscript	Wrote the paper	Writing - Original Draft	YES
3779451	23703906	BGN	2	prepared manuscript|designed experiments and supervised work	designed experiments and supervised work	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Supervision	YES
3779451	23703906	GP	2	performed em and mitochondrial morphometric analysis	performed em and mitochondrial morphometric analysis	Performed the experiments	Investigation	YES
3779451	23703906	JED	2	prepared manuscript|designed experiments and supervised work	prepared manuscript	Wrote the paper	Writing - Original Draft	YES
3779451	23703906	JED	2	prepared manuscript|designed experiments and supervised work	designed experiments and supervised work	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Supervision	YES
3779451	23703906	MEFs	2	immunofluorescence staining, qrt pcr, western blots	immunofluorescence staining, qrt pcr, western blots	Performed the experiments	Investigation	YES
3779451	23703906	NAC	2	treatment and cloning	treatment and cloning	Performed the experiments	Investigation	YES
3779451	23703906	PvdG	2	performed western blots|prepared manuscript	performed western blots	Performed the experiments	Investigation	YES
3779451	23703906	PvdG	2	performed western blots|prepared manuscript	prepared manuscript	Wrote the paper	Writing - Original Draft	YES
3779451	23703906	RK	2	designed and performed ox-ptp and mass spec analysis	designed and performed ox-ptp and mass spec analysis	Conceived and designed the experiments|Performed the experiments	Investigation	YES
3779451	23703906	SEW	2	performed seahorse experiments|prepared manuscript	performed seahorse experiments	Performed the experiments	Investigation	YES
3779451	23703906	SEW	2	performed seahorse experiments|prepared manuscript	prepared manuscript	Wrote the paper	Writing - Original Draft	YES
2034355	17957255	HM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2034355	17957255	HM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2034355	17957255	HM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2034355	17957255	HM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2034355	17957255	LC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2034355	17957255	LC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2034355	17957255	LC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2034355	17957255	RM	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
2034355	17957255	RM	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2034355	17957255	RY	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6051950	30022306	All	PLoS52	the relevant data and materials are presented in the manuscript	the relevant data and materials are presented in the manuscript	-	-	NO
6051950	30022306	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6051950	30022306	DZ	PLoS52	conceived and designed experiments|helped with the written the research paper with	conceived and designed experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6051950	30022306	DZ	PLoS52	conceived and designed experiments|helped with the written the research paper with	helped with the written the research paper with	Wrote the paper	Writing - Original Draft	YES
6051950	30022306	K.C.	PLoS52	in ningbo university	in ningbo university	-	-	NO
6051950	30022306	KW	PLoS52	helped with the written the research paper with	helped with the written the research paper with	Wrote the paper	Writing - Original Draft	YES
6051950	30022306	KY	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
6051950	30022306	KY	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
6051950	30022306	LH	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
6051950	30022306	LL	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
6051950	30022306	The authors	PLoS52	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
6051950	30022306	Wong Magna Fund	PLoS52	in ningbo university	in ningbo university	-	-	NO
6051950	30022306	XH	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
6051950	30022306	ZY	PLoS52	performed the experiments|analyzed the data|written the research paper with	performed the experiments	Performed the experiments	Investigation	YES
6051950	30022306	ZY	PLoS52	performed the experiments|analyzed the data|written the research paper with	analyzed the data	Analyzed the data	Formal analysis	YES
6051950	30022306	ZY	PLoS52	performed the experiments|analyzed the data|written the research paper with	written the research paper with	Wrote the paper	Writing - Original Draft	YES
5717434	29158309	J.K.	2	prepared the figures	prepared the figures	-	Visualization	YES
5717434	29158309	M.T.	2	prepared the figures	prepared the figures	-	Visualization	YES
4418762	25938407	CIC	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418762	25938407	CIC	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418762	25938407	CYH	PLoS5	Conceived and designed the experiments|Recruited the study subjects	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418762	25938407	CYH	PLoS5	Conceived and designed the experiments|Recruited the study subjects	Recruited the study subjects	Performed the experiments	Investigation	YES
4418762	25938407	HSS	PLoS5	Conceived and designed the experiments|Recruited the study subjects	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418762	25938407	HSS	PLoS5	Conceived and designed the experiments|Recruited the study subjects	Recruited the study subjects	Performed the experiments	Investigation	YES
4418762	25938407	WJC	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4418762	25938407	WJC	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418762	25938407	YCL	PLoS5	Conceived and designed the experiments|Recruited the study subjects	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418762	25938407	YCL	PLoS5	Conceived and designed the experiments|Recruited the study subjects	Recruited the study subjects	Performed the experiments	Investigation	YES
4418762	25938407	YLH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418762	25938407	YMH	PLoS5	Contributed reagents/materials/analysis tools|Performed the study design and executed the whole research plan	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418762	25938407	YMH	PLoS5	Contributed reagents/materials/analysis tools|Performed the study design and executed the whole research plan	Performed the study design and executed the whole research plan	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4418762	25938407	YSP	PLoS5	Conceived and designed the experiments|Recruited the study subjects	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418762	25938407	YSP	PLoS5	Conceived and designed the experiments|Recruited the study subjects	Recruited the study subjects	Performed the experiments	Investigation	YES
5833154	29495964	BAR	2	conducted all analyses	conducted all analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5833154	29495964	JM	2	conducted all analyses	conducted all analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5833154	29495964	KP	2	conducted all analyses	conducted all analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5833154	29495964	M.M.	2	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5833154	29495964	RKW	2	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5833154	29495964	SM	2	conducted pacbio experiments	conducted pacbio experiments	Performed the experiments	Investigation	YES
5833154	29495964	V.M.	2	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5833154	29495964	VM	2	conducted pacbio experiments	conducted pacbio experiments	Performed the experiments	Investigation	YES
5833154	29495964	XG	2	conducted all analyses	conducted all analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5833154	29495964	XZ	2	conducted all analyses	conducted all analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5839161	29545819	All authors	2	edited and commented on the manuscript	edited and commented on the manuscript	Wrote the paper	Writing - Review & Editing	YES
5839161	29545819	D-YC	2	conceived this work and designed the experiments|performed most of the experiments|wrote the manuscript	conceived this work and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5839161	29545819	D-YC	2	conceived this work and designed the experiments|performed most of the experiments|wrote the manuscript	performed most of the experiments	Performed the experiments	Investigation	YES
5839161	29545819	D-YC	2	conceived this work and designed the experiments|performed most of the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5839161	29545819	DS	2	conceived this work and designed the experiments|wrote the manuscript	conceived this work and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5839161	29545819	DS	2	conceived this work and designed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5839161	29545819	Z-RC	2	performed most of the experiments|wrote the manuscript	performed most of the experiments	Performed the experiments	Investigation	YES
5839161	29545819	Z-RC	2	performed most of the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4503974	26150161	AC	2	experimental procedures, immunohistochemical data processing	experimental procedures, immunohistochemical data processing	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
4503974	26150161	AF	2	collection of biopsies|microscopic analysis, data collection and/or preparation of figures	collection of biopsies	Performed the experiments	Investigation	YES
4503974	26150161	AF	2	collection of biopsies|microscopic analysis, data collection and/or preparation of figures	microscopic analysis, data collection and/or preparation of figures	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
4503974	26150161	AM	2	collection of biopsies	collection of biopsies	Performed the experiments	Investigation	YES
4503974	26150161	All authors	2	reviewed and contributed to the various draft versions of the manuscript and read and approved the final manuscript	reviewed and contributed to the various draft versions of the manuscript and read and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4503974	26150161	DB	2	collection of biopsies	collection of biopsies	Performed the experiments	Investigation	YES
4503974	26150161	DDM	2	microscopic analysis, data collection and/or preparation of figures	microscopic analysis, data collection and/or preparation of figures	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
4503974	26150161	DM	2	microscopic analysis, data collection and/or preparation of figures	microscopic analysis, data collection and/or preparation of figures	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
4503974	26150161	FS	2	experimental procedures, immunohistochemical data processing	experimental procedures, immunohistochemical data processing	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
4503974	26150161	FT	2	microscopic analysis, data collection and/or preparation of figures	microscopic analysis, data collection and/or preparation of figures	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
4503974	26150161	GA	2	study design|experimental procedures, immunohistochemical data processing	study design	Conceived and designed the experiments	Methodology	YES
4503974	26150161	GA	2	study design|experimental procedures, immunohistochemical data processing	experimental procedures, immunohistochemical data processing	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
4503974	26150161	GC	2	study design|experimental procedures, immunohistochemical data processing	study design	Conceived and designed the experiments	Methodology	YES
4503974	26150161	GC	2	study design|experimental procedures, immunohistochemical data processing	experimental procedures, immunohistochemical data processing	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
4503974	26150161	GR	2	experimental procedures, immunohistochemical data processing	experimental procedures, immunohistochemical data processing	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
4503974	26150161	GS	2	collection of biopsies	collection of biopsies	Performed the experiments	Investigation	YES
4503974	26150161	GV	2	experimental procedures, immunohistochemical data processing|microscopic analysis, data collection and/or preparation of figures	experimental procedures, immunohistochemical data processing	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
4503974	26150161	GV	2	experimental procedures, immunohistochemical data processing|microscopic analysis, data collection and/or preparation of figures	microscopic analysis, data collection and/or preparation of figures	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
6270891	24802984	Gianmauro Numico	7	study concept and design|data analysis and interpretation|drafting of the manuscript	study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6270891	24802984	Gianmauro Numico	7	study concept and design|data analysis and interpretation|drafting of the manuscript	data analysis and interpretation	Analyzed the data	Formal analysis	YES
6270891	24802984	Gianmauro Numico	7	study concept and design|data analysis and interpretation|drafting of the manuscript	drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
6270891	24802984	Giulia Courthod	7	study concept and design|data analysis and interpretation|drafting of the manuscript	study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6270891	24802984	Giulia Courthod	7	study concept and design|data analysis and interpretation|drafting of the manuscript	data analysis and interpretation	Analyzed the data	Formal analysis	YES
6270891	24802984	Giulia Courthod	7	study concept and design|data analysis and interpretation|drafting of the manuscript	drafting of the manuscript	Wrote the paper	Writing - Original Draft	YES
6270891	24802984	Loredana Palermo	7	acquisition of literature data|data analysis and interpretation	acquisition of literature data	Performed the experiments	Investigation	YES
6270891	24802984	Loredana Palermo	7	acquisition of literature data|data analysis and interpretation	data analysis and interpretation	Analyzed the data	Formal analysis	YES
6270891	24802984	Pierfrancesco Franco	7	acquisition of literature data|data analysis and interpretation	acquisition of literature data	Performed the experiments	Investigation	YES
6270891	24802984	Pierfrancesco Franco	7	acquisition of literature data|data analysis and interpretation	data analysis and interpretation	Analyzed the data	Formal analysis	YES
6270891	24802984	Salvatore Pisconti	7	acquisition of literature data|data analysis and interpretation	acquisition of literature data	Performed the experiments	Investigation	YES
6270891	24802984	Salvatore Pisconti	7	acquisition of literature data|data analysis and interpretation	data analysis and interpretation	Analyzed the data	Formal analysis	YES
5518149	28729906	TK	2	planned, prepared, and wrote all this review manuscript	planned, prepared, and wrote all this review manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
4418763	25938442	AC	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418763	25938442	CL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418763	25938442	CL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418763	25938442	CL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418763	25938442	CL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418763	25938442	DT	PLoS5	Proofread the manuscript	Proofread the manuscript	-	-	NO
4418763	25938442	GH	PLoS5	Proofread the manuscript	Proofread the manuscript	-	-	NO
4418763	25938442	JS	PLoS5	Proofread the manuscript	Proofread the manuscript	-	-	NO
4418763	25938442	LW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418763	25938442	TW	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418763	25938442	XZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418763	25938442	ZC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4418763	25938442	ZC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
6270892	24481115	Chun-Gui Yang	PLoS52	performed the isolated and identified experiments	performed the isolated and identified experiments	Performed the experiments	Investigation	YES
6270892	24481115	Du-Qiang Luo	PLoS52	conceived and designed the study|wrote the paper|reviewed and edited the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6270892	24481115	Du-Qiang Luo	PLoS52	conceived and designed the study|wrote the paper|reviewed and edited the manuscript	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270892	24481115	Du-Qiang Luo	PLoS52	conceived and designed the study|wrote the paper|reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
6270892	24481115	Lin Li	PLoS52	performed the isolated and identified experiments	performed the isolated and identified experiments	Performed the experiments	Investigation	YES
6270892	24481115	Pei-Yao Wei	PLoS52	performed the isolated and identified experiments	performed the isolated and identified experiments	Performed the experiments	Investigation	YES
6270892	24481115	Xin-Hua Lu	PLoS52	performed biological evaluation	performed biological evaluation	Performed the experiments	Investigation	YES
6270892	24481115	Yu-Peng Chen	PLoS52	performed the isolated and identified experiments|wrote the paper	performed the isolated and identified experiments	Performed the experiments	Investigation	YES
6270892	24481115	Yu-Peng Chen	PLoS52	performed the isolated and identified experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270892	24481115	Zhi-Hui Zheng	PLoS52	performed biological evaluation	performed biological evaluation	Performed the experiments	Investigation	YES
4418764	25938468	CT	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418764	25938468	DW	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418764	25938468	HH	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418764	25938468	HH	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418764	25938468	HH	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418764	25938468	HT	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4418764	25938468	HT	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418764	25938468	JD	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418764	25938468	JG	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418764	25938468	LW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418764	25938468	LW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418764	25938468	LW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418764	25938468	SX	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418764	25938468	WZ	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418764	25938468	XY	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418764	25938468	ZZ	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6056354	30039201	All	2	the data as well as material are disposable at donostia university microbiology departments database as well as in its frozen storage collection	the data as well as material are disposable at donostia university microbiology departments database as well as in its frozen storage collection	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
6056354	30039201	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6056354	30039201	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
3779452	23666755	AA	2	designed and conducted the sirna mouse experiments	designed and conducted the sirna mouse experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3779452	23666755	AS	2	oversaw the whole project	oversaw the whole project	-	Supervision	YES
3779452	23666755	CB	2	oversaw the whole project	oversaw the whole project	-	Supervision	YES
3779452	23666755	RB	2	oversaw the whole project	oversaw the whole project	-	Supervision	YES
3779452	23666755	SR	2	oversaw the whole project	oversaw the whole project	-	Supervision	YES
3779452	23666755	SaH	2	designed and conducted the sirna mouse experiments	designed and conducted the sirna mouse experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3779452	23666755	SeH	2	conducted the senescence experiments	conducted the senescence experiments	Performed the experiments	Investigation	YES
3779452	23666755	TH	2	oversaw the whole project	oversaw the whole project	-	Supervision	YES
3779452	23666755	TR	2	oversaw the whole project	oversaw the whole project	-	Supervision	YES
2034356	17957259	CW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2034356	17957259	CW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2034356	17957259	CW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2034356	17957259	CW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2034356	17957259	CW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2034356	17957259	EZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2034356	17957259	EZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2034356	17957259	EZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2034356	17957259	EZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2034356	17957259	EZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2034356	17957259	IN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2034356	17957259	IN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2034356	17957259	IN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2034356	17957259	IN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2034356	17957259	IN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4598593	26428881	all authors	2	had substantial contributions to the acquisition, analysis, or interpretation of data for the work	had substantial contributions to the acquisition, analysis, or interpretation of data for the work	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
4418765	25938469	HT	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4418765	25938469	HT	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418765	25938469	KI	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4418765	25938469	KI	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418765	25938469	KM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418765	25938469	KM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418765	25938469	KM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418765	25938469	KM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418765	25938469	KT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418765	25938469	KT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418765	25938469	KT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418765	25938469	KT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418765	25938469	MK	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4418765	25938469	MK	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418765	25938469	SS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418765	25938469	SS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418765	25938469	SS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5526253	28770093	EN	2	are advisers for grade system	are advisers for grade system	-	-	NO
5526253	28770093	JS	2	are the systematic review advisers	are the systematic review advisers	-	-	NO
5526253	28770093	ME	2	are the systematic review advisers	are the systematic review advisers	-	-	NO
5526253	28770093	MS	2	are the organizers of the whole project and manuscript preparation	are the organizers of the whole project and manuscript preparation	Wrote the paper	Project administration|Writing - Original Draft	YES
5526253	28770093	RS	2	are the systematic review advisers	are the systematic review advisers	-	-	NO
5526253	28770093	RT	2	are the systematic review advisers	are the systematic review advisers	-	-	NO
5526253	28770093	SH	2	are the organizers of the whole project and manuscript preparation|are the systematic review advisers	are the organizers of the whole project and manuscript preparation	Wrote the paper	Project administration|Writing - Original Draft	YES
5526253	28770093	SH	2	are the organizers of the whole project and manuscript preparation|are the systematic review advisers	are the systematic review advisers	-	-	NO
5526253	28770093	YH	2	are the systematic review advisers	are the systematic review advisers	-	-	NO
5526253	28770093	YN	2	are the systematic review advisers	are the systematic review advisers	-	-	NO
5526253	28770093	YT	2	are advisers for grade system	are advisers for grade system	-	-	NO
5839237	29545813	AJ	2	was responsible for the coordination, data collection and evaluation of the field trials, and contributed to the interpretation of the field trial results and the text of the manuscript	was responsible for the coordination, data collection and evaluation of the field trials, and contributed to the interpretation of the field trial results and the text of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Project administration|Writing - Original Draft	YES
5839237	29545813	H-JK	2	developed the basic concept of the field trials, conducted the respective statistical data evaluation and developed most of the figures and tables, and wrote substantial parts of the text	developed the basic concept of the field trials, conducted the respective statistical data evaluation and developed most of the figures and tables, and wrote substantial parts of the text	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Visualization|Writing - Original Draft	YES
5839237	29545813	KT	2	analyzed the survey data including the respective statistical calculations and interpreted the results	analyzed the survey data including the respective statistical calculations and interpreted the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5839237	29545813	NS	2	was responsible for developing the farm survey, arrangement of the corresponding table and figure, and wrote parts of the manuscript|analyzed the survey data including the respective statistical calculations and interpreted the results	was responsible for developing the farm survey, arrangement of the corresponding table and figure, and wrote parts of the manuscript	Performed the experiments|Wrote the paper	Investigation|Visualization|Writing - Original Draft	YES
5839237	29545813	NS	2	was responsible for developing the farm survey, arrangement of the corresponding table and figure, and wrote parts of the manuscript|analyzed the survey data including the respective statistical calculations and interpreted the results	analyzed the survey data including the respective statistical calculations and interpreted the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5834837	29499642	ACR	2	designed the research|analyzed and interpreted the data|drafted the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
5834837	29499642	ACR	2	designed the research|analyzed and interpreted the data|drafted the manuscript	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5834837	29499642	ACR	2	designed the research|analyzed and interpreted the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5834837	29499642	AJA	2	designed the research|analyzed and interpreted the data|drafted the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
5834837	29499642	AJA	2	designed the research|analyzed and interpreted the data|drafted the manuscript	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5834837	29499642	AJA	2	designed the research|analyzed and interpreted the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5834837	29499642	ANT	2	collected data|analyzed and interpreted the data	collected data	Performed the experiments	Investigation	YES
5834837	29499642	ANT	2	collected data|analyzed and interpreted the data	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5834837	29499642	CBK	2	designed the research|collected data|analyzed and interpreted the data|drafted the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
5834837	29499642	CBK	2	designed the research|collected data|analyzed and interpreted the data|drafted the manuscript	collected data	Performed the experiments	Investigation	YES
5834837	29499642	CBK	2	designed the research|collected data|analyzed and interpreted the data|drafted the manuscript	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5834837	29499642	CBK	2	designed the research|collected data|analyzed and interpreted the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5834837	29499642	DLT	2	designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
5834837	29499642	DSS	2	analyzed and interpreted the data	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5834837	29499642	HC	2	collected data	collected data	Performed the experiments	Investigation	YES
5834837	29499642	JAB	2	collected data|analyzed and interpreted the data	collected data	Performed the experiments	Investigation	YES
5834837	29499642	JAB	2	collected data|analyzed and interpreted the data	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5834837	29499642	JRM	2	analyzed and interpreted the data	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5834837	29499642	LTJ	2	collected data	collected data	Performed the experiments	Investigation	YES
5834837	29499642	XW	2	designed the research|analyzed and interpreted the data|drafted the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
5834837	29499642	XW	2	designed the research|analyzed and interpreted the data|drafted the manuscript	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5834837	29499642	XW	2	designed the research|analyzed and interpreted the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5834837	29499642	Y-LT	2	analyzed and interpreted the data	analyzed and interpreted the data	Analyzed the data	Formal analysis	YES
5834837	29499642	all authors	2	provided critical revisions of the manuscript, and read and approved the final manuscript	provided critical revisions of the manuscript, and read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6270893	24914894	Hong Hu	4	The manuscript was revised by	The manuscript was revised by	Wrote the paper	Writing - Review & Editing	YES
6270893	24914894	Huawen Hu	4	The study was designed by|and the data were analyzed and the manuscript was written by	The study was designed by	Conceived and designed the experiments	Methodology	YES
6270893	24914894	Huawen Hu	4	The study was designed by|and the data were analyzed and the manuscript was written by	and the data were analyzed and the manuscript was written by	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6270893	24914894	John H. Xin	4	The manuscript was revised by	The manuscript was revised by	Wrote the paper	Writing - Review & Editing	YES
6270893	24914894	Xiaowen Wang	4	A part of the characterization work was assisted by	A part of the characterization work was assisted by	Performed the experiments	Investigation	YES
6270893	24914894	Xinkun Lu	4	A part of the characterization work was assisted by	A part of the characterization work was assisted by	Performed the experiments	Investigation	YES
2034409	17971854	AT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2034409	17971854	AT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2034409	17971854	AT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2034409	17971854	AT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2034409	17971854	AT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2034409	17971854	BK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2034409	17971854	BK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2034409	17971854	BK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2034409	17971854	BK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2034409	17971854	GG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
2034409	17971854	GG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2034409	17971854	GR	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
2034409	17971854	GR	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2034409	17971854	JM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2034409	17971854	JM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2034409	17971854	JM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2034409	17971854	JM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2034409	17971854	JN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2034409	17971854	JN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2034409	17971854	JN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2034409	17971854	JN	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2034409	17971854	NS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
2034409	17971854	NS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
6057861	30043199	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6057861	30043199	IAn	2	planned and executed the experiments, collected and calculated all data, created graphs and figures and drafted this manuscript	planned and executed the experiments, collected and calculated all data, created graphs and figures and drafted this manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Visualization|Writing - Original Draft	YES
6057861	30043199	IAp	2	executed the experiments, collected and calculated the data and contributed to scientific discussion	executed the experiments, collected and calculated the data and contributed to scientific discussion	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6057861	30043199	PF	2	executed the experiments, collected and calculated the data and contributed to scientific discussion	executed the experiments, collected and calculated the data and contributed to scientific discussion	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6057861	30043199	RW	2	substantially contributed to conception and design of conducted experiments	substantially contributed to conception and design of conducted experiments	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
3779453	23629957	JP	2	conceived the hypothesis, designed and performed experiments, analysed the data and wrote the manuscript	conceived the hypothesis, designed and performed experiments, analysed the data and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
3779453	23629957	PES	2	conceived the hypothesis, designed experiments and wrote the manuscript	conceived the hypothesis, designed experiments and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
3779453	23629957	TSM	2	performed experiments and analysed the data	performed experiments and analysed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4418766	25938455	AS	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418766	25938455	AS	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418766	25938455	DT	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418766	25938455	DT	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418766	25938455	DT	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418766	25938455	MJW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418766	25938455	MJW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418766	25938455	MJW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418766	25938455	MJW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418766	25938455	MJW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418766	25938455	OP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418766	25938455	OP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418766	25938455	OP	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5840156	29552021	HR	PLoS5	Conceived idea and designed the experiments|Conducted the experiments|Analyzed the data|Wrote the article	Conceived idea and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5840156	29552021	HR	PLoS5	Conceived idea and designed the experiments|Conducted the experiments|Analyzed the data|Wrote the article	Conducted the experiments	Performed the experiments	Investigation	YES
5840156	29552021	HR	PLoS5	Conceived idea and designed the experiments|Conducted the experiments|Analyzed the data|Wrote the article	Analyzed the data	Analyzed the data	Formal analysis	YES
5840156	29552021	HR	PLoS5	Conceived idea and designed the experiments|Conducted the experiments|Analyzed the data|Wrote the article	Wrote the article	Wrote the paper	Writing - Original Draft	YES
5840156	29552021	NW	PLoS5	Conducted the experiments	Conducted the experiments	Performed the experiments	Investigation	YES
5840156	29552021	S-HK	PLoS5	Conceived idea and designed the experiments|Analyzed the data|Provided the materials and resources|Wrote the article	Conceived idea and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5840156	29552021	S-HK	PLoS5	Conceived idea and designed the experiments|Analyzed the data|Provided the materials and resources|Wrote the article	Analyzed the data	Analyzed the data	Formal analysis	YES
5840156	29552021	S-HK	PLoS5	Conceived idea and designed the experiments|Analyzed the data|Provided the materials and resources|Wrote the article	Provided the materials and resources	Contributed reagents/materials/analysis tools	Resources	YES
5840156	29552021	S-HK	PLoS5	Conceived idea and designed the experiments|Analyzed the data|Provided the materials and resources|Wrote the article	Wrote the article	Wrote the paper	Writing - Original Draft	YES
5840156	29552021	SD	PLoS5	Provided the materials and resources|Wrote the article	Provided the materials and resources	Contributed reagents/materials/analysis tools	Resources	YES
5840156	29552021	SD	PLoS5	Provided the materials and resources|Wrote the article	Wrote the article	Wrote the paper	Writing - Original Draft	YES
5840156	29552021	VVE	PLoS5	Conducted the experiments|Wrote the article	Conducted the experiments	Performed the experiments	Investigation	YES
5840156	29552021	VVE	PLoS5	Conducted the experiments|Wrote the article	Wrote the article	Wrote the paper	Writing - Original Draft	YES
6270894	25237756	CD	2	have designed research and all the authors wrote the paper	have designed research and all the authors wrote the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
6270894	25237756	JL	2	have designed research and all the authors wrote the paper	have designed research and all the authors wrote the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
6270894	25237756	JPF	2	have designed research and all the authors wrote the paper	have designed research and all the authors wrote the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4668297	26665005	Dario Conte	2	prepared the paper	prepared the paper	Wrote the paper	Writing - Original Draft	YES
4668297	26665005	Federica Branchi	2	managed and elaborated the database	managed and elaborated the database	Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Software	YES
4668297	26665005	Francesca Ferretti	2	managed and elaborated the database	managed and elaborated the database	Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Software	YES
4668297	26665005	Leda Roncoroni	2	managed and elaborated the database	managed and elaborated the database	Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Software	YES
4668297	26665005	Luca Elli	2	prepared the paper	prepared the paper	Wrote the paper	Writing - Original Draft	YES
5834899	29499650	BHZ	2	wrote the manuscript|developed the software	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5834899	29499650	BHZ	2	wrote the manuscript|developed the software	developed the software	Contributed reagents/materials/analysis tools	Software	YES
5834899	29499650	GCX	2	participated in data simulation	participated in data simulation	-	Formal analysis	YES
5834899	29499650	JTL	2	conceived and supervised this project|wrote the manuscript	conceived and supervised this project	Conceived and designed the experiments	Conceptualization|Supervision	YES
5834899	29499650	JTL	2	conceived and supervised this project|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5834899	29499650	JX	2	developed the software|participated in data simulation	developed the software	Contributed reagents/materials/analysis tools	Software	YES
5834899	29499650	JX	2	developed the software|participated in data simulation	participated in data simulation	-	Formal analysis	YES
5834899	29499650	MYS	2	participated in data simulation	participated in data simulation	-	Formal analysis	YES
5834899	29499650	WX	2	developed the software	developed the software	Contributed reagents/materials/analysis tools	Software	YES
2034529	17971852	HT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2034529	17971852	HT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2034529	17971852	HT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2034529	17971852	XZ	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
2034529	17971852	XZ	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
6072643	30073560	All authors	2	have contributed to this research work|read and approved the final manuscript	have contributed to this research work	Performed the experiments	Investigation	YES
6072643	30073560	All authors	2	have contributed to this research work|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
3779454	23606570	IJF	2	with the	with the	-	-	NO
3779454	23606570	all authors	2	assisted ijf with the	assisted ijf with the	-	-	NO
4598595	26428883	EF	2	immunohistochemistry performing, manuscript writing contribution, figures preparation, microscopic analysis and data collection	immunohistochemistry performing, manuscript writing contribution, figures preparation, microscopic analysis and data collection	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Visualization|Writing - Original Draft	YES
4598595	26428883	GS	2	project design, manuscript writing contribution, microscopic analysis and data collection	project design, manuscript writing contribution, microscopic analysis and data collection	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
4598595	26428883	LM	2	manuscript writing contribution, microscopic analysis and data collection	manuscript writing contribution, microscopic analysis and data collection	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft	YES
5543591	28794881	AV	2	participated in drafting and revising the manuscript	participated in drafting and revising the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5543591	28794881	KR	2	participated in drafting and revising the manuscript	participated in drafting and revising the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5543591	28794881	LS	2	participated in drafting and revising the manuscript	participated in drafting and revising the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5543591	28794881	MG	2	participated in drafting and revising the manuscript	participated in drafting and revising the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5543591	28794881	SK	2	participated in drafting and revising the manuscript	participated in drafting and revising the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5543591	28794881	SR	2	participated in drafting and revising the manuscript	participated in drafting and revising the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5543591	28794881	VM	2	participated in drafting and revising the manuscript	participated in drafting and revising the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4418768	25938511	H. Zhou	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418768	25938511	H. Zhou	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418768	25938511	H. Zhu	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418768	25938511	HJL	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4418768	25938511	HJL	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418768	25938511	LJ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418768	25938511	QCZ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418768	25938511	YBZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418768	25938511	YBZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418768	25938511	YBZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418768	25938511	YBZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418768	25938511	YQC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418768	25938511	YZ	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4418768	25938511	YZ	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418768	25938511	ZX	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
6270895	24714193	I.K.	2	contributed to the characterization of the compounds	contributed to the characterization of the compounds	Performed the experiments	Investigation	YES
6270895	24714193	L.S.	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6270895	24714193	S.V.C.	2	wrote the manuscript|coordinated this study	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6270895	24714193	S.V.C.	2	wrote the manuscript|coordinated this study	coordinated this study	-	Project administration	YES
6270895	24714193	T.K.H.	2	contributed to the characterization of the compounds	contributed to the characterization of the compounds	Performed the experiments	Investigation	YES
2034530	17971861	IK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2034530	17971861	IK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2034530	17971861	IK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2034530	17971861	KD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2034530	17971861	KD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2034530	17971861	KD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2034530	17971861	SM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4598596	26428884	HH	2	study conception and design, data analysis and interpretation, critical review, final approval	study conception and design, data analysis and interpretation, critical review, final approval	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
4598596	26428884	JP	2	study conception and design, data analysis and interpretation, manuscript drafting and final approval	study conception and design, data analysis and interpretation, manuscript drafting and final approval	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
4598596	26428884	JR	2	study conception and design, critical literature review, data acquisition, analysis and interpretation, manuscript drafting and final approval	study conception and design, critical literature review, data acquisition, analysis and interpretation, manuscript drafting and final approval	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
4598596	26428884	PJ	2	study conception and design, data acquisition	study conception and design, data acquisition	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
5840855	29552022	AF	2	contributed to arabidopsis characterization and revising the manuscript	contributed to arabidopsis characterization and revising the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5840855	29552022	CR	2	contributed to the soybean characterization and arabidopsis phenotyping	contributed to the soybean characterization and arabidopsis phenotyping	Performed the experiments	Investigation	YES
5840855	29552022	EC	2	performed soybean phenotyping	performed soybean phenotyping	Performed the experiments	Investigation	YES
5840855	29552022	JG	2	performed the ssh library, generated and analyzed the arabidopsis transgenic plants	performed the ssh library, generated and analyzed the arabidopsis transgenic plants	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5840855	29552022	OB	2	supervised the soybean characterization, provided suggestions, and revised the manuscript	supervised the soybean characterization, provided suggestions, and revised the manuscript	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Review & Editing	YES
5840855	29552022	SV	2	conceived and directed this study, analyzed the data, and wrote the manuscript	conceived and directed this study, analyzed the data, and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Supervision|Writing - Original Draft	YES
5840855	29552022	VB	2	contributed to the library analysis and provided suggestions	contributed to the library analysis and provided suggestions	Contributed reagents/materials/analysis tools	Resources	YES
5834901	29499648	CQC	2	performed the qrt-pcr analysis and in situ hybridation	performed the qrt-pcr analysis and in situ hybridation	Performed the experiments	Investigation	YES
5834901	29499648	FHZ	2	conducted the sequence analysis and wrote the manuscript	conducted the sequence analysis and wrote the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5834901	29499648	JBL	2	performed the qrt-pcr analysis and in situ hybridation	performed the qrt-pcr analysis and in situ hybridation	Performed the experiments	Investigation	YES
5834901	29499648	JL	2	performed the qrt-pcr analysis and in situ hybridation	performed the qrt-pcr analysis and in situ hybridation	Performed the experiments	Investigation	YES
5834901	29499648	JSC	2	conducted the sequence analysis and wrote the manuscript	conducted the sequence analysis and wrote the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5834901	29499648	LH	2	carried out the experiment, analyzed the data, and drafted the manuscript	carried out the experiment, analyzed the data, and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5834901	29499648	LJK	2	performed the qrt-pcr analysis and in situ hybridation	performed the qrt-pcr analysis and in situ hybridation	Performed the experiments	Investigation	YES
5834901	29499648	LMM	2	carried out the experiment, analyzed the data, and drafted the manuscript|conducted the sequence analysis and wrote the manuscript	carried out the experiment, analyzed the data, and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5834901	29499648	LMM	2	carried out the experiment, analyzed the data, and drafted the manuscript|conducted the sequence analysis and wrote the manuscript	conducted the sequence analysis and wrote the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5834901	29499648	QZC	2	carried out the experiment, analyzed the data, and drafted the manuscript	carried out the experiment, analyzed the data, and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5834901	29499648	SYW	2	performed the qrt-pcr analysis and in situ hybridation	performed the qrt-pcr analysis and in situ hybridation	Performed the experiments	Investigation	YES
5834901	29499648	XLY	2	designed and supervised the research and gave final approval of the version to be published	designed and supervised the research and gave final approval of the version to be published	Conceived and designed the experiments	Methodology|Supervision	YES
5834901	29499648	YXL	2	carried out the experiment, analyzed the data, and drafted the manuscript	carried out the experiment, analyzed the data, and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6076874	30078153	AS	2	participated in the experimental design, carried out the experiments and drafted the manuscript	participated in the experimental design, carried out the experiments and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
6076874	30078153	All	2	authors read and approved the final manuscript	authors read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6076874	30078153	CAII	2	authors read and approved the final manuscript	authors read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6076874	30078153	CY	2	designed the experiments and wrote the manuscript	designed the experiments and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4598597	26428885	HZ	2	concept and design, data acquisition and interpretation, article drafting, manuscript planning and writing	concept and design, data acquisition and interpretation, article drafting, manuscript planning and writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4598597	26428885	SP	2	experimental assistance	experimental assistance	-	-	NO
4598597	26428885	SZ	2	experimental work, study execution and manuscript writing	experimental work, study execution and manuscript writing	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4598597	26428885	TG	2	experimental work, study execution and manuscript writing	experimental work, study execution and manuscript writing	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4598597	26428885	ZZ	2	technical assistance	technical assistance	Performed the experiments	Investigation	YES
5545034	28794882	AKL	2	were involved in critical revision of the manuscript	were involved in critical revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5545034	28794882	HK	2	contributed to the protocol development of the study, and collection and interpretation of patient data	contributed to the protocol development of the study, and collection and interpretation of patient data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Methodology|Resources	YES
5545034	28794882	HM	2	contributed to the protocol development of the study, and collection and interpretation of patient data	contributed to the protocol development of the study, and collection and interpretation of patient data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Methodology|Resources	YES
5545034	28794882	KO	2	were involved in critical revision of the manuscript	were involved in critical revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5545034	28794882	MS	2	was involved in the conception and design of the study, and critical revision of the manuscript	was involved in the conception and design of the study, and critical revision of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
5545034	28794882	TKa	2	contributed to the protocol development of the study, and collection and interpretation of patient data	contributed to the protocol development of the study, and collection and interpretation of patient data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Methodology|Resources	YES
5545034	28794882	TKo	2	contributed to the protocol development of the study, and collection and interpretation of patient data	contributed to the protocol development of the study, and collection and interpretation of patient data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Methodology|Resources	YES
5545034	28794882	TM	2	contributed to the protocol development of the study, and collection and interpretation of patient data	contributed to the protocol development of the study, and collection and interpretation of patient data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Methodology|Resources	YES
5545034	28794882	UM	2	designed the study, analyzed the data, and drafted the manuscript	designed the study, analyzed the data, and drafted the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5545034	28794882	YI	2	contributed to the protocol development of the study, and collection and interpretation of patient data	contributed to the protocol development of the study, and collection and interpretation of patient data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Methodology|Resources	YES
4251525	25372628	B.W.	2	are co-first authors	are co-first authors	-	-	NO
4251525	25372628	Q.Z.	2	are co-first authors	are co-first authors	-	-	NO
4251525	25372628	R.M.M.	2	are co-first authors	are co-first authors	-	-	NO
4251525	25372628	R.V.	2	are co-first authors	are co-first authors	-	-	NO
4251525	25372628	SS	2	are co-first authors	are co-first authors	-	-	NO
4251525	25372628	Z.M.S.	2	are co-first authors	are co-first authors	-	-	NO
4418770	25938500	CMS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4418770	25938500	CMS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418770	25938500	FKN	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418770	25938500	FKN	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418770	25938500	HWM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418770	25938500	HWM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418770	25938500	HWM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418770	25938500	JV	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4418770	25938500	JV	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418770	25938500	KL	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4418770	25938500	KL	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418770	25938500	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418770	25938500	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418770	25938500	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418770	25938500	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418770	25938500	TL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418770	25938500	TL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418770	25938500	TL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418770	25938500	TL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418770	25938500	VS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4418770	25938500	VS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2034531	17971853	AB	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
2034531	17971853	AB	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2034531	17971853	BP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
2034531	17971853	BR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2034531	17971853	BR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2034531	17971853	BR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2034531	17971853	BR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2034531	17971853	BR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2034531	17971853	EK	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2034531	17971853	EK	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2034531	17971853	ET	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2034531	17971853	ET	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2034531	17971853	FC	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
2034531	17971853	FC	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2034531	17971853	FN	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2034531	17971853	FN	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2034531	17971853	KP	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
2034531	17971853	KP	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2034531	17971853	MB	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
2034531	17971853	MB	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2034531	17971853	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2034531	17971853	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2034531	17971853	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2034531	17971853	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2034531	17971853	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2034531	17971853	NA	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2034531	17971853	NA	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2034531	17971853	QC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2034531	17971853	QC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2034531	17971853	QC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2034531	17971853	RP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2034531	17971853	RP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2034531	17971853	RP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2034531	17971853	RS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2034531	17971853	RS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2034531	17971853	RS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2034531	17971853	RS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2034531	17971853	UL	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2034531	17971853	UL	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2034531	17971853	VV	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
2034531	17971853	VV	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5836443	29506485	DNS	2	and hbw3 designed and performed the animal experiment|isolated rna from the liver samples, labeled, hybridized and scanned the oligo microarrays|conducted the qrt-pcr analysis, completed statistical analysis of the qrt-pcr analysis dataset, and wrote the first draft of the manuscript	and hbw3 designed and performed the animal experiment	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5836443	29506485	DNS	2	and hbw3 designed and performed the animal experiment|isolated rna from the liver samples, labeled, hybridized and scanned the oligo microarrays|conducted the qrt-pcr analysis, completed statistical analysis of the qrt-pcr analysis dataset, and wrote the first draft of the manuscript	isolated rna from the liver samples, labeled, hybridized and scanned the oligo microarrays	Performed the experiments	Investigation	YES
5836443	29506485	DNS	2	and hbw3 designed and performed the animal experiment|isolated rna from the liver samples, labeled, hybridized and scanned the oligo microarrays|conducted the qrt-pcr analysis, completed statistical analysis of the qrt-pcr analysis dataset, and wrote the first draft of the manuscript	conducted the qrt-pcr analysis, completed statistical analysis of the qrt-pcr analysis dataset, and wrote the first draft of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5836443	29506485	LAC	2	secured funding|and hbw3 designed and performed the animal experiment	secured funding	-	Funding acquisition	YES
5836443	29506485	LAC	2	secured funding|and hbw3 designed and performed the animal experiment	and hbw3 designed and performed the animal experiment	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5836443	29506485	NT	2	and hbw3 designed and performed the animal experiment|isolated rna from the liver samples, labeled, hybridized and scanned the oligo microarrays|conducted the qrt-pcr analysis, completed statistical analysis of the qrt-pcr analysis dataset, and wrote the first draft of the manuscript	and hbw3 designed and performed the animal experiment	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5836443	29506485	NT	2	and hbw3 designed and performed the animal experiment|isolated rna from the liver samples, labeled, hybridized and scanned the oligo microarrays|conducted the qrt-pcr analysis, completed statistical analysis of the qrt-pcr analysis dataset, and wrote the first draft of the manuscript	isolated rna from the liver samples, labeled, hybridized and scanned the oligo microarrays	Performed the experiments	Investigation	YES
5836443	29506485	NT	2	and hbw3 designed and performed the animal experiment|isolated rna from the liver samples, labeled, hybridized and scanned the oligo microarrays|conducted the qrt-pcr analysis, completed statistical analysis of the qrt-pcr analysis dataset, and wrote the first draft of the manuscript	conducted the qrt-pcr analysis, completed statistical analysis of the qrt-pcr analysis dataset, and wrote the first draft of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5836443	29506485	WC	2	and hbw3 designed and performed the animal experiment	and hbw3 designed and performed the animal experiment	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5836443	29506485	XW	2	and hbw3 designed and performed the animal experiment	and hbw3 designed and performed the animal experiment	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4598598	26428886	HZ	2	experiments performing, data analysis, manuscript drafting|assisting in sample collection and all experiments, and in manuscript revision	experiments performing, data analysis, manuscript drafting	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4598598	26428886	HZ	2	experiments performing, data analysis, manuscript drafting|assisting in sample collection and all experiments, and in manuscript revision	assisting in sample collection and all experiments, and in manuscript revision	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4598598	26428886	JZ	2	experiments performing, data analysis, manuscript drafting	experiments performing, data analysis, manuscript drafting	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4598598	26428886	LW	2	experiments performing, data analysis, manuscript drafting	experiments performing, data analysis, manuscript drafting	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4598598	26428886	QL	2	assisting in sample collection and all experiments, and in manuscript revision	assisting in sample collection and all experiments, and in manuscript revision	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4598598	26428886	QW	2	study design and supervision, and manuscript revision	study design and supervision, and manuscript revision	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Review & Editing	YES
4598598	26428886	XS	2	assisting in sample collection and all experiments, and in manuscript revision	assisting in sample collection and all experiments, and in manuscript revision	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4598598	26428886	YH	2	study design and supervision, and manuscript revision	study design and supervision, and manuscript revision	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Review & Editing	YES
4598598	26428886	YW	2	experiments performing, data analysis, manuscript drafting	experiments performing, data analysis, manuscript drafting	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4598598	26428886	ZY	2	study design and supervision, and manuscript revision	study design and supervision, and manuscript revision	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Review & Editing	YES
5549373	28808577	DJ	2	read, edited, and approved the final manuscript	read, edited, and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5549373	28808577	JS	2	read, edited, and approved the final manuscript	read, edited, and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5549373	28808577	MP	2	wrote the manuscript and conducted the data extraction from the medical record and literature search|read, edited, and approved the final manuscript	wrote the manuscript and conducted the data extraction from the medical record and literature search	Analyzed the data|Wrote the paper	Data curation|Formal analysis|Writing - Original Draft	YES
5549373	28808577	MP	2	wrote the manuscript and conducted the data extraction from the medical record and literature search|read, edited, and approved the final manuscript	read, edited, and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5549373	28808577	PK	2	wrote the manuscript and conducted the data extraction from the medical record and literature search|read, edited, and approved the final manuscript	wrote the manuscript and conducted the data extraction from the medical record and literature search	Analyzed the data|Wrote the paper	Data curation|Formal analysis|Writing - Original Draft	YES
5549373	28808577	PK	2	wrote the manuscript and conducted the data extraction from the medical record and literature search|read, edited, and approved the final manuscript	read, edited, and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5549373	28808577	WF	2	read, edited, and approved the final manuscript	read, edited, and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5549373	28808577	WT	2	read, edited, and approved the final manuscript	read, edited, and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5841052	29552020	AGBR	2	generated lab and field data	generated lab and field data	Performed the experiments	Investigation	YES
5841052	29552020	AR	2	helped in data analysis	helped in data analysis	Analyzed the data	Formal analysis	YES
5841052	29552020	ARR	2	generated lab and field data|drafted the manuscript	generated lab and field data	Performed the experiments	Investigation	YES
5841052	29552020	ARR	2	generated lab and field data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5841052	29552020	CS	2	provided technical guidance during the conduct of research work|drafted the manuscript	provided technical guidance during the conduct of research work	Performed the experiments	Investigation|Supervision	YES
5841052	29552020	CS	2	provided technical guidance during the conduct of research work|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5841052	29552020	LA	2	provided technical guidance during the conduct of research work	provided technical guidance during the conduct of research work	Performed the experiments	Investigation|Supervision	YES
5841052	29552020	MM	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5841052	29552020	PK	2	generated lab and field data	generated lab and field data	Performed the experiments	Investigation	YES
5841052	29552020	RG	2	provided technical guidance during the conduct of research work|drafted the manuscript	provided technical guidance during the conduct of research work	Performed the experiments	Investigation|Supervision	YES
5841052	29552020	RG	2	provided technical guidance during the conduct of research work|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5841052	29552020	RS	2	planned and coordinated this study|provided technical guidance during the conduct of research work|drafted the manuscript|critically revised the paper for final publication	planned and coordinated this study	Conceived and designed the experiments	Conceptualization|Project administration	YES
5841052	29552020	RS	2	planned and coordinated this study|provided technical guidance during the conduct of research work|drafted the manuscript|critically revised the paper for final publication	provided technical guidance during the conduct of research work	Performed the experiments	Investigation|Supervision	YES
5841052	29552020	RS	2	planned and coordinated this study|provided technical guidance during the conduct of research work|drafted the manuscript|critically revised the paper for final publication	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5841052	29552020	RS	2	planned and coordinated this study|provided technical guidance during the conduct of research work|drafted the manuscript|critically revised the paper for final publication	critically revised the paper for final publication	Wrote the paper	Writing - Review & Editing	YES
5841052	29552020	RY	2	provided technical guidance during the conduct of research work|drafted the manuscript	provided technical guidance during the conduct of research work	Performed the experiments	Investigation|Supervision	YES
5841052	29552020	RY	2	provided technical guidance during the conduct of research work|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5841052	29552020	SK	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
6270897	25401399	AG	PLoS52	performed experiments, analyzed the data and interpreted the results	performed experiments, analyzed the data and interpreted the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270897	25401399	AR	PLoS52	defined the research subject|designed the experiments|performed experiments, analyzed the data and interpreted the results|wrote the paper	defined the research subject	-	-	NO
6270897	25401399	AR	PLoS52	defined the research subject|designed the experiments|performed experiments, analyzed the data and interpreted the results|wrote the paper	designed the experiments	Conceived and designed the experiments	Methodology	YES
6270897	25401399	AR	PLoS52	defined the research subject|designed the experiments|performed experiments, analyzed the data and interpreted the results|wrote the paper	performed experiments, analyzed the data and interpreted the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270897	25401399	AR	PLoS52	defined the research subject|designed the experiments|performed experiments, analyzed the data and interpreted the results|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270897	25401399	All authors	PLoS52	have contributed to the manuscript	have contributed to the manuscript	-	-	NO
6270897	25401399	GG	PLoS52	defined the research subject	defined the research subject	-	-	NO
6270897	25401399	WS	PLoS52	defined the research subject	defined the research subject	-	-	NO
6270897	25401399	ZK	PLoS52	defined the research subject	defined the research subject	-	-	NO
2034532	17971855	DM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2034532	17971855	DM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2034532	17971855	DM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2034532	17971855	DP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2034532	17971855	DP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2034532	17971855	DP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2034532	17971855	MS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2034532	17971855	MS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2034532	17971855	MS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2034532	17971855	PB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2034532	17971855	PB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2034532	17971855	PB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2034532	17971855	PB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2034532	17971855	RP	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
2034532	17971855	RP	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2034532	17971855	TF	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2034532	17971855	TF	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2034532	17971855	TF	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4598599	26428887	DEK	2	design, critical review, data collection, analysis and interpretation, draft of manuscript, final approval	design, critical review, data collection, analysis and interpretation, draft of manuscript, final approval	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
4598599	26428887	EGS	2	data collection, analysis and interpretation, draft of manuscript, final approval	data collection, analysis and interpretation, draft of manuscript, final approval	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4598599	26428887	IPG	2	design, data analysis and interpretation, critical literature review, draft of manuscript, final approval	design, data analysis and interpretation, critical literature review, draft of manuscript, final approval	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
4598599	26428887	OVK	2	data collection, analysis and interpretation, final approval	data collection, analysis and interpretation, final approval	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4418795	25938476	CB	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418795	25938476	DA	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418795	25938476	DA	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418795	25938476	JSL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418795	25938476	LES	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418795	25938476	LES	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418795	25938476	LES	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418795	25938476	LEV	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418795	25938476	LEV	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418795	25938476	SC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418795	25938476	SC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418795	25938476	SC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418795	25938476	SC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418795	25938476	SSR	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418795	25938476	SSR	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418795	25938476	SSR	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6077290	30083848	AG	2	participated in conducting the experiments	participated in conducting the experiments	Performed the experiments	Investigation	YES
6077290	30083848	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6077290	30083848	KHK	2	developed the concept, designed and performed the experiments|fully participated in data interpretation and drafted the manuscript|wrote the manuscript	developed the concept, designed and performed the experiments	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
6077290	30083848	KHK	2	developed the concept, designed and performed the experiments|fully participated in data interpretation and drafted the manuscript|wrote the manuscript	fully participated in data interpretation and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6077290	30083848	KHK	2	developed the concept, designed and performed the experiments|fully participated in data interpretation and drafted the manuscript|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6077290	30083848	PD	2	participated in conducting the experiments	participated in conducting the experiments	Performed the experiments	Investigation	YES
6077290	30083848	RB	2	participated in conducting the experiments	participated in conducting the experiments	Performed the experiments	Investigation	YES
6077290	30083848	TK	2	developed the concept, designed and performed the experiments|fully participated in data interpretation and drafted the manuscript	developed the concept, designed and performed the experiments	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
6077290	30083848	TK	2	developed the concept, designed and performed the experiments|fully participated in data interpretation and drafted the manuscript	fully participated in data interpretation and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6077290	30083848	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5836817	29504898	AC	2	were responsible for patient care, the selection of patients recruited in this study, the generation and interpretation of clinical data	were responsible for patient care, the selection of patients recruited in this study, the generation and interpretation of clinical data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5836817	29504898	AG	2	performed general supervision of the research group	performed general supervision of the research group	Performed the experiments	Investigation|Supervision	YES
5836817	29504898	EA	2	conceived and designed the experiments, sequenced, assembled and annotated the genomes of strains, and microbiome data|participated in data interpretation|were responsible for patient care, the selection of patients recruited in this study, the generation and interpretation of clinical data	conceived and designed the experiments, sequenced, assembled and annotated the genomes of strains, and microbiome data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Data curation|Investigation|Methodology	YES
5836817	29504898	EA	2	conceived and designed the experiments, sequenced, assembled and annotated the genomes of strains, and microbiome data|participated in data interpretation|were responsible for patient care, the selection of patients recruited in this study, the generation and interpretation of clinical data	participated in data interpretation	Analyzed the data	Formal analysis	YES
5836817	29504898	EA	2	conceived and designed the experiments, sequenced, assembled and annotated the genomes of strains, and microbiome data|participated in data interpretation|were responsible for patient care, the selection of patients recruited in this study, the generation and interpretation of clinical data	were responsible for patient care, the selection of patients recruited in this study, the generation and interpretation of clinical data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5836817	29504898	MK	2	conceived and designed the experiments, sequenced, assembled and annotated the genomes of strains, and microbiome data|performed resistome analysis and assisted in the preparation of figures and text	conceived and designed the experiments, sequenced, assembled and annotated the genomes of strains, and microbiome data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Data curation|Investigation|Methodology	YES
5836817	29504898	MK	2	conceived and designed the experiments, sequenced, assembled and annotated the genomes of strains, and microbiome data|performed resistome analysis and assisted in the preparation of figures and text	performed resistome analysis and assisted in the preparation of figures and text	Performed the experiments	Investigation|Visualization	YES
5836817	29504898	NR	2	conceived and designed the experiments, sequenced, assembled and annotated the genomes of strains, and microbiome data|was responsible for the microbiome analysis and data presentation, and contributed to manuscript writing	conceived and designed the experiments, sequenced, assembled and annotated the genomes of strains, and microbiome data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Data curation|Investigation|Methodology	YES
5836817	29504898	NR	2	conceived and designed the experiments, sequenced, assembled and annotated the genomes of strains, and microbiome data|was responsible for the microbiome analysis and data presentation, and contributed to manuscript writing	was responsible for the microbiome analysis and data presentation, and contributed to manuscript writing	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5836817	29504898	NS	2	conceived and designed the experiments, sequenced, assembled and annotated the genomes of strains, and microbiome data	conceived and designed the experiments, sequenced, assembled and annotated the genomes of strains, and microbiome data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Data curation|Investigation|Methodology	YES
5836817	29504898	OV	2	conceived and designed the experiments, sequenced, assembled and annotated the genomes of strains, and microbiome data|supervised the study and contributed to manuscript writing	conceived and designed the experiments, sequenced, assembled and annotated the genomes of strains, and microbiome data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Data curation|Investigation|Methodology	YES
5836817	29504898	OV	2	conceived and designed the experiments, sequenced, assembled and annotated the genomes of strains, and microbiome data|supervised the study and contributed to manuscript writing	supervised the study and contributed to manuscript writing	Wrote the paper	Supervision|Writing - Original Draft	YES
5549394	28808576	All authors	2	contributed equally to the manuscript	contributed equally to the manuscript	-	-	NO
5841092	29552023	AF	2	designed experiments and performed transient transformations, nucleic acid extractions, quantitative pcr, data analysis, and drafted and edited the manuscript	designed experiments and performed transient transformations, nucleic acid extractions, quantitative pcr, data analysis, and drafted and edited the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5841092	29552023	LL	2	designed and evaluated sgrnas, performed the in vitro cas9 assay, led vector construction and validation, transformed and validated somatic embryos, and contributed to drafting the manuscript	designed and evaluated sgrnas, performed the in vitro cas9 assay, led vector construction and validation, transformed and validated somatic embryos, and contributed to drafting the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Validation|Writing - Original Draft	YES
5841092	29552023	MG	2	developed the project, oversaw experimental progress, and contributed to drafting and editing the manuscript	developed the project, oversaw experimental progress, and contributed to drafting and editing the manuscript	Wrote the paper	Supervision|Writing - Original Draft|Writing - Review & Editing	YES
5841092	29552023	SM	2	developed the project, oversaw experimental progress, and contributed to drafting and editing the manuscript	developed the project, oversaw experimental progress, and contributed to drafting and editing the manuscript	Wrote the paper	Supervision|Writing - Original Draft|Writing - Review & Editing	YES
5745332	29254961	C.J.H.	2	prepared the figures together	prepared the figures together	-	Visualization	YES
5745332	29254961	J.L.M.	2	prepared the figures together|prepared the figures together	prepared the figures together	-	Visualization	YES
5745332	29254961	J.L.M.	2	prepared the figures together|prepared the figures together	prepared the figures together	-	Visualization	YES
4598600	26428888	EML	2	experiments design, research performing, manuscript writing	experiments design, research performing, manuscript writing	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
4598600	26428888	EOM	2	experiments design, research performing, manuscript writing	experiments design, research performing, manuscript writing	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
4598600	26428888	GG	2	western blot assays	western blot assays	Performed the experiments	Investigation	YES
4598600	26428888	OR	2	histologic interpretation	histologic interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4598600	26428888	VNGH	2	experiments design, research performing, manuscript writing	experiments design, research performing, manuscript writing	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
2034533	17971849	CC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
2034533	17971849	CC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2034533	17971849	EG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2034533	17971849	EG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
2034533	17971849	EG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2034533	17971849	FOValle	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2034533	17971849	FOValle	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
2034533	17971849	FOValle	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2034533	17971849	FOliver	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2034533	17971849	FOliver	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2034533	17971849	FOliver	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2034533	17971849	FOliver	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2034533	17971849	FOliver	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2034533	17971849	MD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2034533	17971849	MD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2034533	17971849	MD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2034533	17971849	MD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2034533	17971849	MD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2034533	17971849	RA	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
2034533	17971849	RM	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2034533	17971849	RM	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418798	25938588	CE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418798	25938588	CE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418798	25938588	CE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418798	25938588	CE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418798	25938588	CE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418798	25938588	FB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418798	25938588	FB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418798	25938588	FB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418798	25938588	FB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418798	25938588	FB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418798	25938588	HH	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418798	25938588	HH	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418798	25938588	LR	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418798	25938588	LR	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418798	25938588	SC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418798	25938588	SC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418798	25938588	SC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418798	25938588	SC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418798	25938588	SC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418798	25938588	TJ	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418798	25938588	TJ	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3799488	23922331	CW	2	designed experiments|performed experiments|analysed data and wrote the manuscript	designed experiments	Conceived and designed the experiments	Methodology	YES
3799488	23922331	CW	2	designed experiments|performed experiments|analysed data and wrote the manuscript	performed experiments	Performed the experiments	Investigation	YES
3799488	23922331	CW	2	designed experiments|performed experiments|analysed data and wrote the manuscript	analysed data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3799488	23922331	PJS	2	designed experiments|performed experiments	designed experiments	Conceived and designed the experiments	Methodology	YES
3799488	23922331	PJS	2	designed experiments|performed experiments	performed experiments	Performed the experiments	Investigation	YES
3799488	23922331	SF	2	designed experiments|analysed data and wrote the manuscript	designed experiments	Conceived and designed the experiments	Methodology	YES
3799488	23922331	SF	2	designed experiments|analysed data and wrote the manuscript	analysed data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6270898	25153865	A.M.G.	2	performed the bibliographic research, analyzed and discussed the main results in the literature and wrote the manuscript	performed the bibliographic research, analyzed and discussed the main results in the literature and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6270898	25153865	A.Q.P.	2	discussed the main results and performed the revision of the manuscript	discussed the main results and performed the revision of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
6270898	25153865	C.J.M.	2	was involved in all the corrections and critical analysis of the manuscript	was involved in all the corrections and critical analysis of the manuscript	Wrote the paper	Writing - Review & Editing	YES
6270898	25153865	F.M.S.	2	performed the bibliographic research, analyzed and discussed the main results in the literature and wrote the manuscript	performed the bibliographic research, analyzed and discussed the main results in the literature and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6270898	25153865	J.A.Q.	2	supervised the contents design, discuss data, corrections and critical analysis of the manuscript	supervised the contents design, discuss data, corrections and critical analysis of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Supervision|Writing - Review & Editing	YES
6270898	25153865	L.A.P.	2	supervised the contents design, discuss data, corrections and critical analysis of the manuscript	supervised the contents design, discuss data, corrections and critical analysis of the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Supervision|Writing - Review & Editing	YES
6270898	25153865	L.M.M.	2	analyzed and discussed the main results of the revised version	analyzed and discussed the main results of the revised version	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5563025	28828174	JWFF	2	contributed to study design and reviewed the paper	contributed to study design and reviewed the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5563025	28828174	MNFJ	2	contributed to study design, data collection, and data analysis and reviewed the paper	contributed to study design, data collection, and data analysis and reviewed the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Review & Editing	YES
5563025	28828174	WLN	2	contributed to the study design, data collection, and data analysis	contributed to the study design, data collection, and data analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Methodology|Resources	YES
6077291	30083943	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6077291	30083943	BV	2	idealized the project, performed the experiments and drafted the manuscript	idealized the project, performed the experiments and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
6077291	30083943	GD	2	carried out the statistical design and designed and supervised experiments	carried out the statistical design and designed and supervised experiments	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology|Supervision	YES
6077291	30083943	JAT	2	supervised all project and reviewed all manuscript	supervised all project and reviewed all manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
6077291	30083943	JCT	2	contributed solving troubleshooting problems and reviewing manuscript	contributed solving troubleshooting problems and reviewing manuscript	Wrote the paper	Writing - Review & Editing	YES
6077291	30083943	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5836819	29504918	AB	2	are guest editors of this journal issue|wrote the manuscript	are guest editors of this journal issue	-	-	NO
5836819	29504918	AB	2	are guest editors of this journal issue|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5836819	29504918	NK	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5836819	29504918	RH	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5836819	29504918	YO	2	are guest editors of this journal issue|wrote the manuscript	are guest editors of this journal issue	-	-	NO
5836819	29504918	YO	2	are guest editors of this journal issue|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5841119	29552024	CM	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5841119	29552024	CM	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5841119	29552024	NR	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5841119	29552024	SW	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5841119	29552024	SW	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5841119	29552024	XJ	PLoS52	conceived and designed the experiments|contributed reagents, materials, analysis tools|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5841119	29552024	XJ	PLoS52	conceived and designed the experiments|contributed reagents, materials, analysis tools|wrote the paper	contributed reagents, materials, analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5841119	29552024	XJ	PLoS52	conceived and designed the experiments|contributed reagents, materials, analysis tools|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5841119	29552024	YX	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5841119	29552024	YZ	PLoS52	conceived and designed the experiments|analyzed the data|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5841119	29552024	YZ	PLoS52	conceived and designed the experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5841119	29552024	YZ	PLoS52	conceived and designed the experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5745335	29254964	G.D.A.	2	conceived the project|designed and led the research, and interpreted the data with input from all authors|conducted tof-sims analyses and interpretation|undertook xps analyses and interpretation|wrote the first draft of the manuscript	conceived the project	Conceived and designed the experiments	Conceptualization	YES
5745335	29254964	G.D.A.	2	conceived the project|designed and led the research, and interpreted the data with input from all authors|conducted tof-sims analyses and interpretation|undertook xps analyses and interpretation|wrote the first draft of the manuscript	designed and led the research, and interpreted the data with input from all authors	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5745335	29254964	G.D.A.	2	conceived the project|designed and led the research, and interpreted the data with input from all authors|conducted tof-sims analyses and interpretation|undertook xps analyses and interpretation|wrote the first draft of the manuscript	conducted tof-sims analyses and interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5745335	29254964	G.D.A.	2	conceived the project|designed and led the research, and interpreted the data with input from all authors|conducted tof-sims analyses and interpretation|undertook xps analyses and interpretation|wrote the first draft of the manuscript	undertook xps analyses and interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5745335	29254964	G.D.A.	2	conceived the project|designed and led the research, and interpreted the data with input from all authors|conducted tof-sims analyses and interpretation|undertook xps analyses and interpretation|wrote the first draft of the manuscript	wrote the first draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
5745335	29254964	I.W.F.	2	conducted tof-sims analyses and interpretation	conducted tof-sims analyses and interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5745335	29254964	S.T.	2	undertook xps analyses and interpretation	undertook xps analyses and interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5745335	29254964	all authors	2	discussed results and contributed to the manuscript	discussed results and contributed to the manuscript	-	-	NO
2034534	17971859	KL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
2034534	17971859	KL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2034534	17971859	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2034534	17971859	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2034534	17971859	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2034534	17971859	MS	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2034534	17971859	SL	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2034534	17971859	SL	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2034534	17971859	SL	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2034534	17971859	SL	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5585957	28904799	JT	2	edited the manuscript	edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
4260631	25412144	Y.B.	2	contributed equally	contributed equally	-	-	NO
4260631	25412144	Y.Y.	2	contributed equally	contributed equally	-	-	NO
3799489	23857777	CC	1	Analysis and interpretation of data	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
3799489	23857777	CDL	1	Analysis and interpretation of data|Drafting the manuscript and critical revision	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
3799489	23857777	CDL	1	Analysis and interpretation of data|Drafting the manuscript and critical revision	Drafting the manuscript and critical revision	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3799489	23857777	FCB	1	Analysis and interpretation of data	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
3799489	23857777	HW	1	Analysis and interpretation of data	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
3799489	23857777	JF	1	Analysis and interpretation of data	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
3799489	23857777	JPH	1	Analysis and interpretation of data|Drafting the manuscript and critical revision	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
3799489	23857777	JPH	1	Analysis and interpretation of data|Drafting the manuscript and critical revision	Drafting the manuscript and critical revision	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3799489	23857777	JY	1	Study concept and design|Acquisition of data|Analysis and interpretation of data|Drafting the manuscript and critical revision	Study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
3799489	23857777	JY	1	Study concept and design|Acquisition of data|Analysis and interpretation of data|Drafting the manuscript and critical revision	Acquisition of data	Performed the experiments	Investigation	YES
3799489	23857777	JY	1	Study concept and design|Acquisition of data|Analysis and interpretation of data|Drafting the manuscript and critical revision	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
3799489	23857777	JY	1	Study concept and design|Acquisition of data|Analysis and interpretation of data|Drafting the manuscript and critical revision	Drafting the manuscript and critical revision	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3799489	23857777	MEFZ	1	Analysis and interpretation of data|Drafting the manuscript and critical revision	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
3799489	23857777	MEFZ	1	Analysis and interpretation of data|Drafting the manuscript and critical revision	Drafting the manuscript and critical revision	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3799489	23857777	ML	1	Study concept and design|Acquisition of data|Analysis and interpretation of data|Drafting the manuscript and critical revision	Study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
3799489	23857777	ML	1	Study concept and design|Acquisition of data|Analysis and interpretation of data|Drafting the manuscript and critical revision	Acquisition of data	Performed the experiments	Investigation	YES
3799489	23857777	ML	1	Study concept and design|Acquisition of data|Analysis and interpretation of data|Drafting the manuscript and critical revision	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
3799489	23857777	ML	1	Study concept and design|Acquisition of data|Analysis and interpretation of data|Drafting the manuscript and critical revision	Drafting the manuscript and critical revision	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3799489	23857777	PJC	1	Analysis and interpretation of data|Drafting the manuscript and critical revision	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
3799489	23857777	PJC	1	Analysis and interpretation of data|Drafting the manuscript and critical revision	Drafting the manuscript and critical revision	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3799489	23857777	QY	1	Analysis and interpretation of data	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
3799489	23857777	SEH	1	Analysis and interpretation of data	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
3799489	23857777	VFZ	1	Acquisition of data|Analysis and interpretation of data	Acquisition of data	Performed the experiments	Investigation	YES
3799489	23857777	VFZ	1	Acquisition of data|Analysis and interpretation of data	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
3799489	23857777	WEF	1	Analysis and interpretation of data	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
3799489	23857777	XC	1	Study concept and design|Acquisition of data|Analysis and interpretation of data|Drafting the manuscript and critical revision	Study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
3799489	23857777	XC	1	Study concept and design|Acquisition of data|Analysis and interpretation of data|Drafting the manuscript and critical revision	Acquisition of data	Performed the experiments	Investigation	YES
3799489	23857777	XC	1	Study concept and design|Acquisition of data|Analysis and interpretation of data|Drafting the manuscript and critical revision	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
3799489	23857777	XC	1	Study concept and design|Acquisition of data|Analysis and interpretation of data|Drafting the manuscript and critical revision	Drafting the manuscript and critical revision	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3799489	23857777	XY	1	Acquisition of data|Analysis and interpretation of data	Acquisition of data	Performed the experiments	Investigation	YES
3799489	23857777	XY	1	Acquisition of data|Analysis and interpretation of data	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
3799489	23857777	YC	1	Analysis and interpretation of data|Drafting the manuscript and critical revision	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
3799489	23857777	YC	1	Analysis and interpretation of data|Drafting the manuscript and critical revision	Drafting the manuscript and critical revision	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3799489	23857777	YZ	1	Study concept and design|Acquisition of data|Analysis and interpretation of data|Drafting the manuscript and critical revision	Study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
3799489	23857777	YZ	1	Study concept and design|Acquisition of data|Analysis and interpretation of data|Drafting the manuscript and critical revision	Acquisition of data	Performed the experiments	Investigation	YES
3799489	23857777	YZ	1	Study concept and design|Acquisition of data|Analysis and interpretation of data|Drafting the manuscript and critical revision	Analysis and interpretation of data	Analyzed the data	Formal analysis	YES
3799489	23857777	YZ	1	Study concept and design|Acquisition of data|Analysis and interpretation of data|Drafting the manuscript and critical revision	Drafting the manuscript and critical revision	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4418809	25938501	APG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418809	25938501	APG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418809	25938501	APG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418809	25938501	APG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418809	25938501	APM	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418809	25938501	APM	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418809	25938501	EFL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418809	25938501	EFL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418809	25938501	EFL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418809	25938501	GHF	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418809	25938501	GHF	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418809	25938501	GHF	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418809	25938501	JAG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418809	25938501	JAG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418809	25938501	JAG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418809	25938501	JAG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418809	25938501	JPT	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418809	25938501	JPT	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418809	25938501	JPT	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418809	25938501	RPB	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418809	25938501	RPB	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418809	25938501	SVS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418809	25938501	SVS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418809	25938501	SVS	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270899	25268723	C.P.	2	aided in the experiments and revised the manuscript	aided in the experiments and revised the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
6270899	25268723	D.A.G.C.	2	conceived, designed, and supervised the study, evaluated the results, and aided in drafting and revision of the manuscript	conceived, designed, and supervised the study, evaluated the results, and aided in drafting and revision of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
6270899	25268723	D.F.F.	2	conceived the study, performed all the experimentation, acquisition and analysis of data and drafting of the manuscript	conceived the study, performed all the experimentation, acquisition and analysis of data and drafting of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
6270899	25268723	E.J.P.	2	aided in the experiments and revised the manuscript	aided in the experiments and revised the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
6270899	25268723	L.Z.S.B.	2	aided in the experiments and revised the manuscript	aided in the experiments and revised the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5844958	29556243	CS	2	performed the morphological measurements	performed the morphological measurements	Performed the experiments	Investigation	YES
5844958	29556243	EF	2	designed the experiments and wrote the manuscript	designed the experiments and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5844958	29556243	EL	2	handled the rna sequencing data	handled the rna sequencing data	Performed the experiments	Investigation	YES
5844958	29556243	EbB	2	performed the morphological measurements	performed the morphological measurements	Performed the experiments	Investigation	YES
5844958	29556243	EnB	2	performed the ion content measurements	performed the ion content measurements	Performed the experiments	Investigation	YES
5844958	29556243	FLS	2	planned the experiments, wrote and edited the manuscript	planned the experiments, wrote and edited the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
5844958	29556243	GP	2	carried out pam imaging analyses	carried out pam imaging analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
5844958	29556243	GS	2	performed the ion content measurements	performed the ion content measurements	Performed the experiments	Investigation	YES
5844958	29556243	PF	2	performed the pathway enrichment analyses	performed the pathway enrichment analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5844958	29556243	PS	2	handled the openarray data	handled the openarray data	Performed the experiments	Investigation	YES
5844958	29556243	SR	2	performed the pathway enrichment analyses	performed the pathway enrichment analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5844958	29556243	ST	2	handled the rna sequencing data	handled the rna sequencing data	Performed the experiments	Investigation	YES
5844958	29556243	TM	2	carried out pam imaging analyses	carried out pam imaging analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
6079112	30083790	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6079112	30083790	The authors	2	would like to express their gratitude to all the members of the flagship project|declare that they have no competing interests	would like to express their gratitude to all the members of the flagship project	-	-	NO
6079112	30083790	The authors	2	would like to express their gratitude to all the members of the flagship project|declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5745338	29254967	B.J.W.M.	2	performed model simulations	performed model simulations	Performed the experiments	Formal analysis|Investigation|Methodology	YES
5745338	29254967	all authors	2	discussed the outcomes and co-wrote the manuscript	discussed the outcomes and co-wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4598603	26428891	CQ	2	detailed supervision and interpretation of data obtained, manuscript revision	detailed supervision and interpretation of data obtained, manuscript revision	Analyzed the data|Wrote the paper	Formal analysis|Supervision|Writing - Review & Editing	YES
4598603	26428891	KF	2	experimental system design, experiments performing, data collection, manuscript drafting	experimental system design, experiments performing, data collection, manuscript drafting	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
4598603	26428891	OB	2	experiments partial performing, data collection	experiments partial performing, data collection	Performed the experiments	Investigation	YES
4598603	26428891	SS	2	experimental system design and direction, experiments partial performing, manuscript drafting	experimental system design and direction, experiments partial performing, manuscript drafting	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
4598603	26428891	TM	2	experiments partial performing, data collection	experiments partial performing, data collection	Performed the experiments	Investigation	YES
4598603	26428891	TYT	2	experiments partial performing, data collection	experiments partial performing, data collection	Performed the experiments	Investigation	YES
5836822	29504895	DP	2	participated in the back-end development and critical analysis of the results	participated in the back-end development and critical analysis of the results	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Software	YES
5836822	29504895	IT	2	developed the front-end user interface and participated in the back-end development	developed the front-end user interface and participated in the back-end development	Contributed reagents/materials/analysis tools	Software	YES
5836822	29504895	IV	2	conceived the study, guided the project and helped to draft the manuscript	conceived the study, guided the project and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Supervision|Writing - Original Draft	YES
5836822	29504895	TE	2	conceived the methodology, developed and implemented the algorithms of the method, drafted the manuscript and performed the statistical analysis	conceived the methodology, developed and implemented the algorithms of the method, drafted the manuscript and performed the statistical analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Software|Writing - Original Draft	YES
2034536	17957238	AH	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2034536	17957238	AP	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
2034536	17957238	AP	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2034536	17957238	CS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
2034536	17957238	CS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2034536	17957238	HF	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
2034536	17957238	HF	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2034536	17957238	HM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Enrolled patients	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2034536	17957238	HM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Enrolled patients	Performed the experiments	Performed the experiments	Investigation	YES
2034536	17957238	HM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Enrolled patients	Analyzed the data	Analyzed the data	Formal analysis	YES
2034536	17957238	HM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Enrolled patients	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2034536	17957238	HM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Enrolled patients	Enrolled patients	Performed the experiments	Investigation	YES
2034536	17957238	IP	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
2034536	17957238	IP	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2034536	17957238	KW	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
2034536	17957238	KW	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2034536	17957238	NA	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2034536	17957238	NB	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
2034536	17957238	NB	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5613326	28975031	AC	2	conceived the content of this letter and draft the manuscript	conceived the content of this letter and draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5613326	28975031	AG	2	conceived the content of this letter and draft the manuscript	conceived the content of this letter and draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5613326	28975031	CG	2	conceived the content of this letter and draft the manuscript	conceived the content of this letter and draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5613326	28975031	FV	2	conceived the content of this letter and draft the manuscript	conceived the content of this letter and draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5613326	28975031	SMR	2	conceived the content of this letter and draft the manuscript	conceived the content of this letter and draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
3799490	23868506	AB	PLoS52	designed the research|performed the experiments	designed the research	Conceived and designed the experiments	Methodology	YES
3799490	23868506	AB	PLoS52	designed the research|performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
3799490	23868506	AG	PLoS52	designed the research|performed the experiments|wrote the paper	designed the research	Conceived and designed the experiments	Methodology	YES
3799490	23868506	AG	PLoS52	designed the research|performed the experiments|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
3799490	23868506	AG	PLoS52	designed the research|performed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3799490	23868506	IN	PLoS52	designed the research|performed the experiments	designed the research	Conceived and designed the experiments	Methodology	YES
3799490	23868506	IN	PLoS52	designed the research|performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
3799490	23868506	KKM	PLoS52	performed the experiments|performed and analysed rppas	performed the experiments	Performed the experiments	Investigation	YES
3799490	23868506	KKM	PLoS52	performed the experiments|performed and analysed rppas	performed and analysed rppas	Performed the experiments	Investigation	YES
3799490	23868506	LK	PLoS52	performed the tma and analysis	performed the tma and analysis	Performed the experiments	Investigation	YES
3799490	23868506	MS	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
3799490	23868506	MSchl	PLoS52	performed the tma and analysis	performed the tma and analysis	Performed the experiments	Investigation	YES
3799490	23868506	MSchr	PLoS52	performed the tma and analysis	performed the tma and analysis	Performed the experiments	Investigation	YES
3799490	23868506	NC	PLoS52	performed and analysed rppas	performed and analysed rppas	Performed the experiments	Investigation	YES
3799490	23868506	NEH	PLoS52	designed the research|wrote the paper	designed the research	Conceived and designed the experiments	Methodology	YES
3799490	23868506	NEH	PLoS52	designed the research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3799490	23868506	SL	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
3799490	23868506	TCR	PLoS52	performed bioinformatics	performed bioinformatics	Performed the experiments	Formal analysis|Investigation	YES
6270900	25532840	All authors	2	discussed, edited and approved the final version	discussed, edited and approved the final version	Wrote the paper	Writing - Review & Editing	YES
6270900	25532840	C.X.	2	designed the research|performed the experimental work|wrote the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
6270900	25532840	C.X.	2	designed the research|performed the experimental work|wrote the manuscript	performed the experimental work	Performed the experiments	Investigation	YES
6270900	25532840	C.X.	2	designed the research|performed the experimental work|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6270900	25532840	G.S.	2	performed the experimental work	performed the experimental work	Performed the experiments	Investigation	YES
6270900	25532840	G.Y.	2	performed the experimental work	performed the experimental work	Performed the experiments	Investigation	YES
6270900	25532840	R.W.	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6270900	25532840	X.S.	2	designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
5844964	29556244	BEE	2	worked on the visualization of the perspective|acquired the funding and reviewed and edited the manuscript	worked on the visualization of the perspective	Performed the experiments|Analyzed the data	Visualization	YES
5844964	29556244	BEE	2	worked on the visualization of the perspective|acquired the funding and reviewed and edited the manuscript	acquired the funding and reviewed and edited the manuscript	Wrote the paper	Funding acquisition|Writing - Review & Editing	YES
5844964	29556244	CRG	2	conceptualized, reviewed, validated formerly collected the data, and wrote the original draft of the manuscript|worked on the visualization of the perspective	conceptualized, reviewed, validated formerly collected the data, and wrote the original draft of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Validation|Writing - Original Draft|Writing - Review & Editing	YES
5844964	29556244	CRG	2	conceptualized, reviewed, validated formerly collected the data, and wrote the original draft of the manuscript|worked on the visualization of the perspective	worked on the visualization of the perspective	Performed the experiments|Analyzed the data	Visualization	YES
5844964	29556244	CW	2	acquired the funding and reviewed and edited the manuscript	acquired the funding and reviewed and edited the manuscript	Wrote the paper	Funding acquisition|Writing - Review & Editing	YES
6081484	30088183	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6081484	30088183	JK	2	carried out molecular tests	carried out molecular tests	Performed the experiments	Investigation	YES
6081484	30088183	JMZ	2	carried out phylogenetic tree	carried out phylogenetic tree	Performed the experiments	Investigation	YES
6081484	30088183	KN	2	organized sampling and samples selection	organized sampling and samples selection	Performed the experiments	Investigation	YES
6081484	30088183	LjV	2	performed descriptive epidemiology	performed descriptive epidemiology	Performed the experiments	Investigation	YES
6081484	30088183	MS	2	participated in sequence analysis	participated in sequence analysis	Performed the experiments	Investigation	YES
6081484	30088183	SR	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
6081484	30088183	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
6081484	30088183	VM	2	designed and coordinated the study	designed and coordinated the study	Conceived and designed the experiments	Methodology|Project administration	YES
6081484	30088183	VR	2	performed statistical analysis	performed statistical analysis	Analyzed the data	Formal analysis	YES
5745339	29254968	A.J.H.	2	performed research|planned the research and wrote the paper	performed research	Performed the experiments	Investigation	YES
5745339	29254968	A.J.H.	2	performed research|planned the research and wrote the paper	planned the research and wrote the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5745339	29254968	L.D.	2	planned the research and wrote the paper	planned the research and wrote the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
4418810	25938580	AW	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418810	25938580	AW	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4418810	25938580	AW	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418810	25938580	MSL	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418810	25938580	MSL	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4418810	25938580	MSL	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418810	25938580	NE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418810	25938580	NE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418810	25938580	NE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418810	25938580	NE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418810	25938580	NE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418810	25938580	PAN	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418810	25938580	PAN	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4418810	25938580	PAN	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418810	25938580	RLB	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418810	25938580	RLB	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4418810	25938580	RLB	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418810	25938580	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418810	25938580	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418810	25938580	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418810	25938580	SS	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418810	25938580	TS	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418810	25938580	TS	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5836823	29504901	All	2	the coauthors read and approved the final version of the manuscript	the coauthors read and approved the final version of the manuscript	-	-	NO
5836823	29504901	EAR	2	conducted the laboratory assays|were involved in the manuscript preparation	conducted the laboratory assays	Performed the experiments	Investigation	YES
5836823	29504901	EAR	2	conducted the laboratory assays|were involved in the manuscript preparation	were involved in the manuscript preparation	Wrote the paper	Writing - Original Draft	YES
5836823	29504901	KYM	2	conducted the laboratory assays	conducted the laboratory assays	Performed the experiments	Investigation	YES
5836823	29504901	NAM	2	conducted the laboratory assays|were involved in the manuscript preparation	conducted the laboratory assays	Performed the experiments	Investigation	YES
5836823	29504901	NAM	2	conducted the laboratory assays|were involved in the manuscript preparation	were involved in the manuscript preparation	Wrote the paper	Writing - Original Draft	YES
5836823	29504901	NAS	2	are responsible for the concept and design of the study and drafted the manuscript|performed analysis of gene expression data	are responsible for the concept and design of the study and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
5836823	29504901	NAS	2	are responsible for the concept and design of the study and drafted the manuscript|performed analysis of gene expression data	performed analysis of gene expression data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5836823	29504901	NGK	2	are responsible for the concept and design of the study and drafted the manuscript	are responsible for the concept and design of the study and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
2034598	17957264	AA	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2034598	17957264	DB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2034598	17957264	DB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2034598	17957264	DB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2034598	17957264	RH	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2034598	17957264	TB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2034598	17957264	TB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2034598	17957264	TB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5637256	29046809	All authors	2	were involved in the conception and design of the review, the assessment of articles, and the manuscript drafting and revising, and all provided final approval of the version submitted	were involved in the conception and design of the review, the assessment of articles, and the manuscript drafting and revising, and all provided final approval of the version submitted	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
4698609	26708177	HD	2	experimental design, data acquisition and interpretation, manuscript revision and final approval	experimental design, data acquisition and interpretation, manuscript revision and final approval	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Review & Editing	YES
4698609	26708177	SF	2	experimental design, data acquisition and interpretation, manuscript drafting and final approval	experimental design, data acquisition and interpretation, manuscript drafting and final approval	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5844967	29556242	All authors	2	contributed to the writing of this minireview	contributed to the writing of this minireview	Wrote the paper	Writing - Review & Editing	YES
5844967	29556242	JB	2	drew the maize seedling displayed in figure	drew the maize seedling displayed in figure	-	Visualization	YES
3799491	23929599	AQOA-A	2	revised the manuscript, analysed and interpreted the dataset	revised the manuscript, analysed and interpreted the dataset	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
3799491	23929599	All co-authors	2	contributed to the revision of the manuscript	contributed to the revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
3799491	23929599	CWH	2	discussed and edited the manuscript	discussed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
3799491	23929599	HFY	2	revised the manuscript, analysed and interpreted the dataset	revised the manuscript, analysed and interpreted the dataset	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
3799491	23929599	JBZ	2	created the stable cell lines and contributed to discussion	created the stable cell lines and contributed to discussion	Performed the experiments	Investigation	YES
3799491	23929599	JEP	2	designed and performed experiments, analysed data and wrote the paper	designed and performed experiments, analysed data and wrote the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
3799491	23929599	KG	2	performed all mice experiments	performed all mice experiments	Performed the experiments	Investigation	YES
3799491	23929599	KM	2	provided and analysed dataset	provided and analysed dataset	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
3799491	23929599	PJV	2	provided and analysed dataset	provided and analysed dataset	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
3799491	23929599	QZ	2	designed, supervised and revised the manuscript	designed, supervised and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Supervision|Writing - Review & Editing	YES
3799491	23929599	SZ	2	analysed dataset	analysed dataset	Analyzed the data	Formal analysis	YES
3799491	23929599	WJC	2	provided patient samples and aml cell lines	provided patient samples and aml cell lines	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
6270901	24858100	Daoquan Wang	2	provided guidance and suggestions in the synthesis experiments	provided guidance and suggestions in the synthesis experiments	-	Supervision	YES
6270901	24858100	Guanghui Zong	2	provided help in the synthesis experiments	provided help in the synthesis experiments	Performed the experiments	Investigation	YES
6270901	24858100	Jianjun Zhang	2	provided guidance and suggestions for all the experiments and he also provided proper suggestions when wrote and revised the manuscript	provided guidance and suggestions for all the experiments and he also provided proper suggestions when wrote and revised the manuscript	Wrote the paper	Supervision|Writing - Original Draft|Writing - Review & Editing	YES
6270901	24858100	Rui Jiang	2	was in charge of all the synthesis experiments and wrote the manuscript	was in charge of all the synthesis experiments and wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6270901	24858100	Shuhui Jin	2	provided guidance and suggestions in the synthesis experiments	provided guidance and suggestions in the synthesis experiments	-	Supervision	YES
2034600	17957257	CB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2034600	17957257	CB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2034600	17957257	CB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2034600	17957257	CB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2034600	17957257	FS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2034600	17957257	FS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2034600	17957257	FS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2034600	17957257	FS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2034600	17957257	JF	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
2034600	17957257	MP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2034600	17957257	MP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2034600	17957257	MP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2034600	17957257	RW	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2034600	17957257	TM	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
2034600	17957257	TM	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
6086920	30097787	BMS	PLoS52	conceived the method and designed the experiments|analyzed the results and wrote the manuscript	conceived the method and designed the experiments	Conceived and designed the experiments|Performed the experiments	Conceptualization|Methodology	YES
6086920	30097787	BMS	PLoS52	conceived the method and designed the experiments|analyzed the results and wrote the manuscript	analyzed the results and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6086920	30097787	Both authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6086920	30097787	LTS	PLoS52	conceived the method and designed the experiments|performed the experiments|analyzed the results and wrote the manuscript	conceived the method and designed the experiments	Conceived and designed the experiments|Performed the experiments	Conceptualization|Methodology	YES
6086920	30097787	LTS	PLoS52	conceived the method and designed the experiments|performed the experiments|analyzed the results and wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
6086920	30097787	LTS	PLoS52	conceived the method and designed the experiments|performed the experiments|analyzed the results and wrote the manuscript	analyzed the results and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4418811	25938441	CB	PLoS5	Performed the experiments|Gave manuscript input	Performed the experiments	Performed the experiments	Investigation	YES
4418811	25938441	CB	PLoS5	Performed the experiments|Gave manuscript input	Gave manuscript input	-	-	NO
4418811	25938441	MH	PLoS5	Performed the experiments|Gave manuscript input	Performed the experiments	Performed the experiments	Investigation	YES
4418811	25938441	MH	PLoS5	Performed the experiments|Gave manuscript input	Gave manuscript input	-	-	NO
4418811	25938441	MO	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Gave manuscript input	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418811	25938441	MO	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Gave manuscript input	Performed the experiments	Performed the experiments	Investigation	YES
4418811	25938441	MO	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Gave manuscript input	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418811	25938441	MO	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Gave manuscript input	Gave manuscript input	-	-	NO
4418811	25938441	MT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418811	25938441	MT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418811	25938441	MT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418811	25938441	MT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418811	25938441	MT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418811	25938441	MW	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Gave manuscript input	Performed the experiments	Performed the experiments	Investigation	YES
4418811	25938441	MW	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Gave manuscript input	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418811	25938441	MW	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Gave manuscript input	Gave manuscript input	-	-	NO
5836825	29504911	AAL	2	conducted chip and performed dna libraries	conducted chip and performed dna libraries	Performed the experiments	Investigation	YES
5836825	29504911	JAR	2	performed real time pcr	performed real time pcr	Performed the experiments	Investigation	YES
5836825	29504911	NIE	2	contributed equally as first authors|performed the computational analyses|wrote the manuscript	contributed equally as first authors	-	-	NO
5836825	29504911	NIE	2	contributed equally as first authors|performed the computational analyses|wrote the manuscript	performed the computational analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5836825	29504911	NIE	2	contributed equally as first authors|performed the computational analyses|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5836825	29504911	NPB	2	contributed equally as first authors|designed experiments and analyzed behavioral data|conducted chip and performed dna libraries|wrote the manuscript	contributed equally as first authors	-	-	NO
5836825	29504911	NPB	2	contributed equally as first authors|designed experiments and analyzed behavioral data|conducted chip and performed dna libraries|wrote the manuscript	designed experiments and analyzed behavioral data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5836825	29504911	NPB	2	contributed equally as first authors|designed experiments and analyzed behavioral data|conducted chip and performed dna libraries|wrote the manuscript	conducted chip and performed dna libraries	Performed the experiments	Investigation	YES
5836825	29504911	NPB	2	contributed equally as first authors|designed experiments and analyzed behavioral data|conducted chip and performed dna libraries|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5836825	29504911	TIM	2	wrote the manuscript|supervised the study	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5836825	29504911	TIM	2	wrote the manuscript|supervised the study	supervised the study	-	Supervision	YES
5836825	29504911	VVR	2	made rna extractions and primer design	made rna extractions and primer design	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5648492	29075499	All the authors	2	equally contributed to the conception, data collection, statistical analysis, and drafting of the manuscript	equally contributed to the conception, data collection, statistical analysis, and drafting of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Resources|Writing - Original Draft	YES
5844968	29556247	DC	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5844968	29556247	LY	2	helped in drafting the manuscript	helped in drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
5844968	29556247	SW	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5844968	29556247	XD	2	helped in drafting the manuscript	helped in drafting the manuscript	Wrote the paper	Writing - Original Draft	YES
5784047	29292348	A.T.	2	conceived the simulation, discussed the results and wrote the paper|ran the simulations and analysed the data	conceived the simulation, discussed the results and wrote the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
5784047	29292348	A.T.	2	conceived the simulation, discussed the results and wrote the paper|ran the simulations and analysed the data	ran the simulations and analysed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5784047	29292348	M.Z.	2	conceived the simulation, discussed the results and wrote the paper	conceived the simulation, discussed the results and wrote the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
6270902	24531216	Glaudeston Dutra Wulf	2	co-responsible for final crystallography	co-responsible for final crystallography	Performed the experiments	Investigation	YES
6270902	24531216	Helio A. Stefani	2	co-responsible for the synthesis, crystallization and student supervisor	co-responsible for the synthesis, crystallization and student supervisor	-	Supervision	YES
6270902	24531216	Julio Zukerman-Schpector	2	co-responsible for final crystallography, write-up and students supervisor	co-responsible for final crystallography, write-up and students supervisor	Performed the experiments|Wrote the paper	Investigation|Supervision	YES
6270902	24531216	Lucas Sousa Madureira	2	responsible for theoretical calculations	responsible for theoretical calculations	Analyzed the data	Formal analysis	YES
6270902	24531216	N. S. Vasconcelos	2	co-responsible for the synthesis and crystallization	co-responsible for the synthesis and crystallization	-	-	NO
6270902	24531216	R. T. Tiekink	2	responsible for general write-up and co-responsible for final crystallography	responsible for general write-up and co-responsible for final crystallography	Performed the experiments|Wrote the paper	Investigation	YES
6270902	24531216	Seik Weng Ng	2	x-ray responsible for x-ray data collection and initial refinement	x-ray responsible for x-ray data collection and initial refinement	Performed the experiments	Investigation	YES
3799492	23853104	AA	2	carried out the tumour xenograft model|discussed the data and corrected the paper	carried out the tumour xenograft model	Performed the experiments	Investigation|Methodology	YES
3799492	23853104	AA	2	carried out the tumour xenograft model|discussed the data and corrected the paper	discussed the data and corrected the paper	Wrote the paper	Writing - Review & Editing	YES
3799492	23853104	AS	2	provided reagents and the pbabe h-ras v12 vector	provided reagents and the pbabe h-ras v12 vector	Contributed reagents/materials/analysis tools	Resources	YES
3799492	23853104	OE	2	designed the hcc model	designed the hcc model	Conceived and designed the experiments|Performed the experiments	Methodology	YES
3799492	23853104	RP	2	discussed the data and corrected the paper	discussed the data and corrected the paper	Wrote the paper	Writing - Review & Editing	YES
3799492	23853104	SM	2	conceived the study and wrote the manuscript|carried out the tumour xenograft model	conceived the study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
3799492	23853104	SM	2	conceived the study and wrote the manuscript|carried out the tumour xenograft model	carried out the tumour xenograft model	Performed the experiments	Investigation|Methodology	YES
3799492	23853104	SS	2	carried out and scored the ihc staining	carried out and scored the ihc staining	Performed the experiments	Investigation	YES
3799492	23853104	TG	2	conceived the study and wrote the manuscript	conceived the study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
3799492	23853104	VH	2	carried out the tumour xenograft model	carried out the tumour xenograft model	Performed the experiments	Investigation|Methodology	YES
2034602	17971851	AB	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5674760	29142756	All authors	2	contributed equally to the manuscript	contributed equally to the manuscript	-	-	NO
6086921	30097818	AD	PLoS52	conceived and designed the experiments|performed the experiments and analysed the data	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6086921	30097818	AD	PLoS52	conceived and designed the experiments|performed the experiments and analysed the data	performed the experiments and analysed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6086921	30097818	AJ	PLoS52	provided inputs in data interpretation	provided inputs in data interpretation	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6086921	30097818	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6086921	30097818	JLL	PLoS52	conceived and designed the experiments|provided inputs in data interpretation|polished the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6086921	30097818	JLL	PLoS52	conceived and designed the experiments|provided inputs in data interpretation|polished the manuscript	provided inputs in data interpretation	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6086921	30097818	JLL	PLoS52	conceived and designed the experiments|provided inputs in data interpretation|polished the manuscript	polished the manuscript	Wrote the paper	Writing - Review & Editing	YES
6086921	30097818	PR	PLoS52	supervised the thiol assays	supervised the thiol assays	Performed the experiments	Investigation|Supervision	YES
6086921	30097818	SD	PLoS52	conceived and designed the experiments|provided inputs in data interpretation|polished the manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6086921	30097818	SD	PLoS52	conceived and designed the experiments|provided inputs in data interpretation|polished the manuscript	provided inputs in data interpretation	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
6086921	30097818	SD	PLoS52	conceived and designed the experiments|provided inputs in data interpretation|polished the manuscript	polished the manuscript	Wrote the paper	Writing - Review & Editing	YES
5836826	29504906	AAK	CRediT	Formal analysis|investigation	Formal analysis	Analyzed the data	Formal analysis	YES
5836826	29504906	AAK	CRediT	Formal analysis|investigation	investigation	Performed the experiments	Investigation	YES
5836826	29504906	AK	CRediT	Conceptualization|Writing - review and editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
5836826	29504906	AK	CRediT	Conceptualization|Writing - review and editing	Writing - review and editing	Wrote the paper	Writing - Review & Editing	YES
5836826	29504906	EAS	CRediT	Conceptualization|Formal analysis|investigation|Project administration|supervision|Writing - original draft preparation|Writing - review and editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
5836826	29504906	EAS	CRediT	Conceptualization|Formal analysis|investigation|Project administration|supervision|Writing - original draft preparation|Writing - review and editing	Formal analysis	Analyzed the data	Formal analysis	YES
5836826	29504906	EAS	CRediT	Conceptualization|Formal analysis|investigation|Project administration|supervision|Writing - original draft preparation|Writing - review and editing	investigation	Performed the experiments	Investigation	YES
5836826	29504906	EAS	CRediT	Conceptualization|Formal analysis|investigation|Project administration|supervision|Writing - original draft preparation|Writing - review and editing	Project administration	-	Project administration	YES
5836826	29504906	EAS	CRediT	Conceptualization|Formal analysis|investigation|Project administration|supervision|Writing - original draft preparation|Writing - review and editing	supervision	-	Supervision	YES
5836826	29504906	EAS	CRediT	Conceptualization|Formal analysis|investigation|Project administration|supervision|Writing - original draft preparation|Writing - review and editing	Writing - original draft preparation	Wrote the paper	Writing - Original Draft	YES
5836826	29504906	EAS	CRediT	Conceptualization|Formal analysis|investigation|Project administration|supervision|Writing - original draft preparation|Writing - review and editing	Writing - review and editing	Wrote the paper	Writing - Review & Editing	YES
5836826	29504906	EMS	CRediT	Conceptualization|Formal analysis|investigation	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
5836826	29504906	EMS	CRediT	Conceptualization|Formal analysis|investigation	Formal analysis	Analyzed the data	Formal analysis	YES
5836826	29504906	EMS	CRediT	Conceptualization|Formal analysis|investigation	investigation	Performed the experiments	Investigation	YES
5836826	29504906	EMT	CRediT	Formal analysis|investigation	Formal analysis	Analyzed the data	Formal analysis	YES
5836826	29504906	EMT	CRediT	Formal analysis|investigation	investigation	Performed the experiments	Investigation	YES
5836826	29504906	FM	CRediT	Formal analysis|investigation	Formal analysis	Analyzed the data	Formal analysis	YES
5836826	29504906	FM	CRediT	Formal analysis|investigation	investigation	Performed the experiments	Investigation	YES
5836826	29504906	HS	CRediT	Formal analysis|investigation|Writing - review and editing	Formal analysis	Analyzed the data	Formal analysis	YES
5836826	29504906	HS	CRediT	Formal analysis|investigation|Writing - review and editing	investigation	Performed the experiments	Investigation	YES
5836826	29504906	HS	CRediT	Formal analysis|investigation|Writing - review and editing	Writing - review and editing	Wrote the paper	Writing - Review & Editing	YES
5836826	29504906	JD	CRediT	Formal analysis|investigation|Writing - review and editing	Formal analysis	Analyzed the data	Formal analysis	YES
5836826	29504906	JD	CRediT	Formal analysis|investigation|Writing - review and editing	investigation	Performed the experiments	Investigation	YES
5836826	29504906	JD	CRediT	Formal analysis|investigation|Writing - review and editing	Writing - review and editing	Wrote the paper	Writing - Review & Editing	YES
5836826	29504906	JS	CRediT	Formal analysis|investigation	Formal analysis	Analyzed the data	Formal analysis	YES
5836826	29504906	JS	CRediT	Formal analysis|investigation	investigation	Performed the experiments	Investigation	YES
5836826	29504906	JV	CRediT	Formal analysis|investigation	Formal analysis	Analyzed the data	Formal analysis	YES
5836826	29504906	JV	CRediT	Formal analysis|investigation	investigation	Performed the experiments	Investigation	YES
5836826	29504906	MAN	CRediT	Formal analysis|investigation	Formal analysis	Analyzed the data	Formal analysis	YES
5836826	29504906	MAN	CRediT	Formal analysis|investigation	investigation	Performed the experiments	Investigation	YES
5836826	29504906	ZF	CRediT	Formal analysis|investigation	Formal analysis	Analyzed the data	Formal analysis	YES
5836826	29504906	ZF	CRediT	Formal analysis|investigation	investigation	Performed the experiments	Investigation	YES
5844984	29556246	AS	2	designed the experiments and critically analyzed the results and wrote the paper	designed the experiments and critically analyzed the results and wrote the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5844984	29556246	DD	2	designed the experiments and critically analyzed the results and wrote the paper|performed all the experiments	designed the experiments and critically analyzed the results and wrote the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5844984	29556246	DD	2	designed the experiments and critically analyzed the results and wrote the paper|performed all the experiments	performed all the experiments	Performed the experiments	Investigation	YES
5844984	29556246	IM	2	conceptualized the experiments	conceptualized the experiments	Conceived and designed the experiments	Conceptualization	YES
5844984	29556246	ND	2	conceptualized the experiments|designed the experiments and critically analyzed the results and wrote the paper	conceptualized the experiments	Conceived and designed the experiments	Conceptualization	YES
5844984	29556246	ND	2	conceptualized the experiments|designed the experiments and critically analyzed the results and wrote the paper	designed the experiments and critically analyzed the results and wrote the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
4670693	26682217	Bei Lv	2	contributed equally to this work	contributed equally to this work	-	-	NO
4670693	26682217	Yunjia Dai	2	contributed equally to this work	contributed equally to this work	-	-	NO
4418812	25938443	BO	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418812	25938443	BO	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418812	25938443	BO	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418812	25938443	DE	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418812	25938443	DE	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418812	25938443	DE	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418812	25938443	KS	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418812	25938443	RS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418812	25938443	RS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418812	25938443	RS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418812	25938443	RS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3799493	23982944	AM	3	Acquisition of data	Acquisition of data	Performed the experiments	Investigation	YES
3799493	23982944	CC	3	Drafting the article or revising it critically for important intellectual content	Drafting the article or revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3799493	23982944	KI	3	Acquisition of data	Acquisition of data	Performed the experiments	Investigation	YES
3799493	23982944	LL	3	Acquisition of data	Acquisition of data	Performed the experiments	Investigation	YES
3799493	23982944	LYF	3	Acquisition of data	Acquisition of data	Performed the experiments	Investigation	YES
3799493	23982944	MN	3	Acquisition of data	Acquisition of data	Performed the experiments	Investigation	YES
3799493	23982944	WJL	3	Substantial contributions to conception and design|Drafting the article or revising it critically for important intellectual content	Substantial contributions to conception and design	Conceived and designed the experiments	Conceptualization	YES
3799493	23982944	WJL	3	Substantial contributions to conception and design|Drafting the article or revising it critically for important intellectual content	Drafting the article or revising it critically for important intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6270903	25412043	Dan Su	2	designed research|performed research, analyzed the data and wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
6270903	25412043	Dan Su	2	designed research|performed research, analyzed the data and wrote the paper	performed research, analyzed the data and wrote the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6270903	25412043	Feng Xu	2	also participated in the research	also participated in the research	-	-	NO
6270903	25412043	Ming-Ying Shang	2	designed research	designed research	Conceived and designed the experiments	Methodology	YES
6270903	25412043	Shao-Qing Cai	2	designed research	designed research	Conceived and designed the experiments	Methodology	YES
6270903	25412043	Xue-Yan Yang	2	also participated in the research	also participated in the research	-	-	NO
4698611	26708179	DRR	2	study conception and design|manuscript drafting|manuscript revision	study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4698611	26708179	DRR	2	study conception and design|manuscript drafting|manuscript revision	manuscript drafting	Wrote the paper	Writing - Original Draft	YES
4698611	26708179	DRR	2	study conception and design|manuscript drafting|manuscript revision	manuscript revision	Wrote the paper	Writing - Review & Editing	YES
4698611	26708179	GV	2	study conception and design|manuscript revision	study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4698611	26708179	GV	2	study conception and design|manuscript revision	manuscript revision	Wrote the paper	Writing - Review & Editing	YES
4698611	26708179	JM	2	manuscript revision	manuscript revision	Wrote the paper	Writing - Review & Editing	YES
4698611	26708179	JRT	2	study conception and design|manuscript drafting|manuscript revision	study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4698611	26708179	JRT	2	study conception and design|manuscript drafting|manuscript revision	manuscript drafting	Wrote the paper	Writing - Original Draft	YES
4698611	26708179	JRT	2	study conception and design|manuscript drafting|manuscript revision	manuscript revision	Wrote the paper	Writing - Review & Editing	YES
4698611	26708179	TP	2	study conception and design|manuscript revision	study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4698611	26708179	TP	2	study conception and design|manuscript revision	manuscript revision	Wrote the paper	Writing - Review & Editing	YES
5683442	29158899	AKB	2	contributed equally to the manuscript preparation	contributed equally to the manuscript preparation	Wrote the paper	Writing - Original Draft	YES
5683442	29158899	AZ	2	contributed equally to the manuscript preparation	contributed equally to the manuscript preparation	Wrote the paper	Writing - Original Draft	YES
5683442	29158899	BP	2	contributed equally to the manuscript preparation	contributed equally to the manuscript preparation	Wrote the paper	Writing - Original Draft	YES
5683442	29158899	MG	2	contributed equally to the manuscript preparation	contributed equally to the manuscript preparation	Wrote the paper	Writing - Original Draft	YES
5683442	29158899	RKS	2	contributed equally to the design, data acquisition, statistical calculations, and manuscript preparation	contributed equally to the design, data acquisition, statistical calculations, and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft	YES
5683442	29158899	SS	2	contributed equally to the design, data acquisition, statistical calculations, and manuscript preparation	contributed equally to the design, data acquisition, statistical calculations, and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft	YES
5784064	29335368	F.P.	2	co-wrote and co-edited the manuscript	co-wrote and co-edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5784064	29335368	L.H.	2	co-wrote and co-edited the manuscript	co-wrote and co-edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
2034603	17971856	DN	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2034603	17971856	DN	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2034603	17971856	DN	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2034603	17971856	DW	PLoS5	Conceived and designed the experiments|Critical review of manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2034603	17971856	DW	PLoS5	Conceived and designed the experiments|Critical review of manuscript	Critical review of manuscript	Wrote the paper	Writing - Review & Editing	YES
2034603	17971856	HH	PLoS5	Performed the experiments|Analyzed the data|Critical review of manuscript	Performed the experiments	Performed the experiments	Investigation	YES
2034603	17971856	HH	PLoS5	Performed the experiments|Analyzed the data|Critical review of manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
2034603	17971856	HH	PLoS5	Performed the experiments|Analyzed the data|Critical review of manuscript	Critical review of manuscript	Wrote the paper	Writing - Review & Editing	YES
2034603	17971856	MS	PLoS5	Performed the experiments|Critical review of manuscript	Performed the experiments	Performed the experiments	Investigation	YES
2034603	17971856	MS	PLoS5	Performed the experiments|Critical review of manuscript	Critical review of manuscript	Wrote the paper	Writing - Review & Editing	YES
2034603	17971856	NH	PLoS5	Conceived and designed the experiments|Critical review of manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2034603	17971856	NH	PLoS5	Conceived and designed the experiments|Critical review of manuscript	Critical review of manuscript	Wrote the paper	Writing - Review & Editing	YES
5683569	29158900	KK	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5683569	29158900	SN	2	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
4418813	25938489	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418813	25938489	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418813	25938489	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418813	25938489	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418813	25938489	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418813	25938489	SBM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418813	25938489	SBM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418813	25938489	SBM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418813	25938489	SBM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418813	25938489	SBM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3799494	23873704	CZ	2	directed and led the whole research project, and wrote the paper	directed and led the whole research project, and wrote the paper	Wrote the paper	Supervision|Writing - Original Draft	YES
3799494	23873704	EVK	2	provided cad cells and directed the cad cell culture	provided cad cells and directed the cad cell culture	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources|Supervision	YES
3799494	23873704	JL	2	conducted animal behavior study, partial electrophysiology study and data collection	conducted animal behavior study, partial electrophysiology study and data collection	Performed the experiments	Investigation	YES
3799494	23873704	JY	2	was responsible for the design of animal behaviour study and the electrophysiology study, and the manuscript writing	was responsible for the design of animal behaviour study and the electrophysiology study, and the manuscript writing	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
3799494	23873704	JYL	2	performed the mirna-related signalling experiments, animal model of alcohol intake, the mirna expression studies and the data collection	performed the mirna-related signalling experiments, animal model of alcohol intake, the mirna expression studies and the data collection	Performed the experiments	Investigation|Methodology	YES
3799494	23873704	MX	2	conducted the data analysis	conducted the data analysis	Analyzed the data	Formal analysis	YES
3799494	23873704	SQ	2	performed the western blot, qrt pcr and data analysis	performed the western blot, qrt pcr and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3799494	23873704	SW	2	performed the western blot, qrt pcr and data analysis	performed the western blot, qrt pcr and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3799494	23873704	WL	2	performed the western blot, qrt pcr and data analysis	performed the western blot, qrt pcr and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3799494	23873704	XC	2	performed mirna expression studies	performed mirna expression studies	Performed the experiments	Investigation	YES
3799494	23873704	YC	2	performed mirna expression studies	performed mirna expression studies	Performed the experiments	Investigation	YES
3799494	23873704	YG	2	performed electrophysiology study	performed electrophysiology study	Performed the experiments	Investigation	YES
3799494	23873704	YL	2	performed electrophysiology study	performed electrophysiology study	Performed the experiments	Investigation	YES
5845124	29556245	All the authors	PLoS52	reviewed the manuscript and recommended its submission	reviewed the manuscript and recommended its submission	Wrote the paper	Writing - Review & Editing	YES
5845124	29556245	BW	PLoS52	were involved in the experiments	were involved in the experiments	-	-	NO
5845124	29556245	CY	PLoS52	analyzed the data|designed the experiments|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5845124	29556245	CY	PLoS52	analyzed the data|designed the experiments|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5845124	29556245	CY	PLoS52	analyzed the data|designed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5845124	29556245	HL	PLoS52	were involved in the experiments	were involved in the experiments	-	-	NO
5845124	29556245	HZ	PLoS52	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5845124	29556245	LL	PLoS52	performed most of the experiments|analyzed the data|wrote the manuscript	performed most of the experiments	Performed the experiments	Investigation	YES
5845124	29556245	LL	PLoS52	performed most of the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5845124	29556245	LL	PLoS52	performed most of the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5845124	29556245	SH	PLoS52	were involved in the experiments	were involved in the experiments	-	-	NO
5845124	29556245	WX	PLoS52	performed most of the experiments	performed most of the experiments	Performed the experiments	Investigation	YES
6102160	30128639	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6102160	30128639	CSF	PLoS52	performed the research	performed the research	Performed the experiments	Investigation	YES
6102160	30128639	GZ	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
6102160	30128639	JJLL	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
6102160	30128639	JK	PLoS52	performed the research|analyzed the data|wrote the paper	performed the research	Performed the experiments	Investigation	YES
6102160	30128639	JK	PLoS52	performed the research|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
6102160	30128639	JK	PLoS52	performed the research|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6102160	30128639	LY	PLoS52	designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
6102160	30128639	WNC	PLoS52	designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
6102160	30128639	XL	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
2034605	17957254	DC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2034605	17957254	DC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2034605	17957254	DC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2034605	17957254	ED	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2034605	17957254	ED	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2034605	17957254	EF	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
2034605	17957254	EF	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2034605	17957254	FD	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
2034605	17957254	FD	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2034605	17957254	JL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
2034605	17957254	JL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2034605	17957254	MR	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2034605	17957254	RS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
2034605	17957254	RS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
2034605	17957254	RS	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2034605	17957254	VT	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2034605	17957254	VT	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5698959	29201377	DH	2	contributed to the study concept and interpretation of results	contributed to the study concept and interpretation of results	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
5698959	29201377	DMM	2	contributed to the study concept and design, data collection, data analysis, interpretation of results, and drafting of the manuscript	contributed to the study concept and design, data collection, data analysis, interpretation of results, and drafting of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
5698959	29201377	EDM	2	contributed to the analysis and interpretation of data and drafting of the manuscript	contributed to the analysis and interpretation of data and drafting of the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
5698959	29201377	JGB	2	contributed to the study concept and design, data analysis and interpretation, and revising of the manuscript	contributed to the study concept and design, data analysis and interpretation, and revising of the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Methodology|Resources|Writing - Review & Editing	YES
5698959	29201377	MDW	2	contributed to data collection and analysis and interpretation of results	contributed to data collection and analysis and interpretation of results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5698959	29201377	PS	2	conducted the microbiologic sampling sub-study and contributed to the interpretation of results	conducted the microbiologic sampling sub-study and contributed to the interpretation of results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5698959	29201377	RRK	2	participated in primary data collection and analysis, data interpretation, and contributed to the drafting of the manuscript	participated in primary data collection and analysis, data interpretation, and contributed to the drafting of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4670847	26682215	Fatariah Zakaria	2	also carried out the experiment	also carried out the experiment	Performed the experiments	Investigation	YES
4670847	26682215	Mohd Shazwan Mohd	2	also carried out the experiment	also carried out the experiment	Performed the experiments	Investigation	YES
4670847	26682215	Sze Han Ng	2	carried out research experiment and data analysis and wrote the paper	carried out research experiment and data analysis and wrote the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4670847	26682215	Wan Ahmad	2	participated in the design and performance of this study and edited the paper	participated in the design and performance of this study and edited the paper	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
4670847	26682215	Wan Amir Nizam	2	participated in the design and performance of this study and edited the paper	participated in the design and performance of this study and edited the paper	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
4670847	26682215	Wan Rosli Wan	2	defined the intellectual content, edited the paper, and was the guarantor for the entire experiment	defined the intellectual content, edited the paper, and was the guarantor for the entire experiment	Wrote the paper	Writing - Review & Editing	YES
5836829	29504896	AB	2	wrote the manuscript text|carried out the experiments	wrote the manuscript text	Wrote the paper	Writing - Original Draft	YES
5836829	29504896	AB	2	wrote the manuscript text|carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5836829	29504896	AK	2	supervised the bioinformatic research and text of the manuscript	supervised the bioinformatic research and text of the manuscript	Wrote the paper	Formal analysis|Supervision|Writing - Original Draft	YES
5836829	29504896	AM	2	wrote the manuscript text|supervised the bioinformatic research and text of the manuscript	wrote the manuscript text	Wrote the paper	Writing - Original Draft	YES
5836829	29504896	AM	2	wrote the manuscript text|supervised the bioinformatic research and text of the manuscript	supervised the bioinformatic research and text of the manuscript	Wrote the paper	Formal analysis|Supervision|Writing - Original Draft	YES
5836829	29504896	AP	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5836829	29504896	AS	2	wrote the manuscript text|carried out the experiments	wrote the manuscript text	Wrote the paper	Writing - Original Draft	YES
5836829	29504896	AS	2	wrote the manuscript text|carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5836829	29504896	ED	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5836829	29504896	EL	2	carried out the bioinformatic analysis	carried out the bioinformatic analysis	Performed the experiments	Formal analysis|Investigation	YES
5836829	29504896	MS	2	wrote the manuscript text|carried out the experiments	wrote the manuscript text	Wrote the paper	Writing - Original Draft	YES
5836829	29504896	MS	2	wrote the manuscript text|carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5836829	29504896	NZ	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
5836829	29504896	ZG	2	wrote the manuscript text|carried out the bioinformatic analysis	wrote the manuscript text	Wrote the paper	Writing - Original Draft	YES
5836829	29504896	ZG	2	wrote the manuscript text|carried out the bioinformatic analysis	carried out the bioinformatic analysis	Performed the experiments	Formal analysis|Investigation	YES
5784065	29335369	A.S.K.	2	provided field data	provided field data	Contributed reagents/materials/analysis tools	Resources	YES
5784065	29335369	C.E.H.	2	provided field data	provided field data	Contributed reagents/materials/analysis tools	Resources	YES
5784065	29335369	C.M.V.	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5784065	29335369	D.B.L.	2	provided field data	provided field data	Contributed reagents/materials/analysis tools	Resources	YES
5784065	29335369	D.C.D.	2	provided field data	provided field data	Contributed reagents/materials/analysis tools	Resources	YES
5784065	29335369	D.W.W.	2	provided field data	provided field data	Contributed reagents/materials/analysis tools	Resources	YES
5784065	29335369	E.A.	2	provided field data	provided field data	Contributed reagents/materials/analysis tools	Resources	YES
5784065	29335369	E.A.S.	2	provided field data	provided field data	Contributed reagents/materials/analysis tools	Resources	YES
5784065	29335369	E.G.A.M.	2	provided field data	provided field data	Contributed reagents/materials/analysis tools	Resources	YES
5784065	29335369	F.A.J.	2	provided field data	provided field data	Contributed reagents/materials/analysis tools	Resources	YES
5784065	29335369	G.D.	2	provided field data	provided field data	Contributed reagents/materials/analysis tools	Resources	YES
5784065	29335369	G.M.T.	2	carried out laboratory and statistical analyses and helped draft manuscript	carried out laboratory and statistical analyses and helped draft manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5784065	29335369	I.C.T.N.	2	provided field data	provided field data	Contributed reagents/materials/analysis tools	Resources	YES
5784065	29335369	J.E.	2	provided field data	provided field data	Contributed reagents/materials/analysis tools	Resources	YES
5784065	29335369	J.L.B.	2	provided field data	provided field data	Contributed reagents/materials/analysis tools	Resources	YES
5784065	29335369	K.O.	2	provided field data	provided field data	Contributed reagents/materials/analysis tools	Resources	YES
5784065	29335369	M.F.H.	2	designed the study|carried out laboratory and statistical analyses and helped draft manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5784065	29335369	M.F.H.	2	designed the study|carried out laboratory and statistical analyses and helped draft manuscript	carried out laboratory and statistical analyses and helped draft manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5784065	29335369	M.J.P.S.	2	carried out laboratory and statistical analyses and helped draft manuscript	carried out laboratory and statistical analyses and helped draft manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5784065	29335369	N.T.W.	2	provided field data	provided field data	Contributed reagents/materials/analysis tools	Resources	YES
5784065	29335369	P.M.T.	2	provided field data	provided field data	Contributed reagents/materials/analysis tools	Resources	YES
5784065	29335369	R.J.S.	2	provided field data	provided field data	Contributed reagents/materials/analysis tools	Resources	YES
5784065	29335369	R.K.B.	2	provided field data	provided field data	Contributed reagents/materials/analysis tools	Resources	YES
5784065	29335369	R.Y.	2	provided field data	provided field data	Contributed reagents/materials/analysis tools	Resources	YES
5784065	29335369	S.J.S.	2	provided field data	provided field data	Contributed reagents/materials/analysis tools	Resources	YES
5784065	29335369	S.V.	2	provided field data	provided field data	Contributed reagents/materials/analysis tools	Resources	YES
2039703	17971858	CC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2039703	17971858	CC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2039703	17971858	CC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2039703	17971858	HG	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2039703	17971858	LL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2039703	17971858	LL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2039703	17971858	LL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2039703	17971858	LL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2039703	17971858	MW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
2039703	17971858	PF	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2039703	17971858	PF	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
2039703	17971858	PF	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2039703	17971858	VL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2039703	17971858	VL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5699177	29201378	MN	2	helped to draft the manuscript	helped to draft the manuscript	Wrote the paper	Writing - Original Draft	YES
5699177	29201378	RS	2	was responsible for conception of the letter and drafted and revised the manuscript	was responsible for conception of the letter and drafted and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
4418814	25938641	CH	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418814	25938641	CX	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418814	25938641	HL	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418814	25938641	HZ	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4418814	25938641	HZ	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418814	25938641	JW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418814	25938641	JW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418814	25938641	JW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418814	25938641	RX	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418814	25938641	W-XL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418814	25938641	W-XL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418814	25938641	W-XL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418814	25938641	YX	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
3799495	23853117	AN	2	designed, organized, supervised project and wrote the manuscript	designed, organized, supervised project and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Supervision|Writing - Original Draft	YES
3799495	23853117	FJD	2	designed, organized, supervised project and wrote the manuscript	designed, organized, supervised project and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Supervision|Writing - Original Draft	YES
3799495	23853117	GYK	2	designed, organized, supervised project and wrote the manuscript	designed, organized, supervised project and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Supervision|Writing - Original Draft	YES
3799495	23853117	HJP	2	designed and performed the experiments, analysed the data, generated the figures, and wrote the manuscript	designed and performed the experiments, analysed the data, generated the figures, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Visualization|Writing - Original Draft	YES
3799495	23853117	HKS	2	designed and performed the experiments, analysed the data, generated the figures, and wrote the manuscript	designed and performed the experiments, analysed the data, generated the figures, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Visualization|Writing - Original Draft	YES
3799495	23853117	JPL	2	designed, organized, supervised project and wrote the manuscript	designed, organized, supervised project and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Supervision|Writing - Original Draft	YES
3799495	23853117	JWS	2	designed and performed the experiments, analysed the data, generated the figures, and wrote the manuscript	designed and performed the experiments, analysed the data, generated the figures, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Visualization|Writing - Original Draft	YES
3799495	23853117	JYJ	2	designed and performed the experiments, analysed the data, generated the figures, and wrote the manuscript	designed and performed the experiments, analysed the data, generated the figures, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Visualization|Writing - Original Draft	YES
3799495	23853117	KA	2	designed, organized, supervised project and wrote the manuscript	designed, organized, supervised project and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Supervision|Writing - Original Draft	YES
3799495	23853117	KRK	2	designed and performed the experiments, analysed the data, generated the figures, and wrote the manuscript	designed and performed the experiments, analysed the data, generated the figures, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Visualization|Writing - Original Draft	YES
3799495	23853117	MK	2	designed and performed the experiments, analysed the data, generated the figures, and wrote the manuscript	designed and performed the experiments, analysed the data, generated the figures, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Visualization|Writing - Original Draft	YES
3799495	23853117	MS	2	designed, organized, supervised project and wrote the manuscript	designed, organized, supervised project and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Supervision|Writing - Original Draft	YES
3799495	23853117	NF	2	designed, organized, supervised project and wrote the manuscript	designed, organized, supervised project and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Supervision|Writing - Original Draft	YES
3799495	23853117	YC	2	designed, organized, supervised project and wrote the manuscript	designed, organized, supervised project and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Supervision|Writing - Original Draft	YES
3799495	23853117	YSC	2	designed and performed the experiments, analysed the data, generated the figures, and wrote the manuscript	designed and performed the experiments, analysed the data, generated the figures, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Visualization|Writing - Original Draft	YES
4698615	26708183	AM	2	setting up the tibialis anterior needle biopsies technique, data analysis and interpretation, manuscript revision	setting up the tibialis anterior needle biopsies technique, data analysis and interpretation, manuscript revision	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Review & Editing	YES
4698615	26708183	AP	2	rna extraction, manuscript revision	rna extraction, manuscript revision	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4698615	26708183	BF	2	clinical evaluation, data analysis, manuscript revision	clinical evaluation, data analysis, manuscript revision	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4698615	26708183	EC	2	data analysis, manuscript revision	data analysis, manuscript revision	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4698615	26708183	GC	2	muscle histology and immunohistochemistry, fish, manuscript revision	muscle histology and immunohistochemistry, fish, manuscript revision	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4698615	26708183	GM	2	design and conceptualization of the study, histopathological and clinical evaluation, manuscript revision, final approval of the version to be published	design and conceptualization of the study, histopathological and clinical evaluation, manuscript revision, final approval of the version to be published	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Writing - Review & Editing	YES
4698615	26708183	LV	2	setting up the tibialis anterior needle biopsies technique, manuscript revision	setting up the tibialis anterior needle biopsies technique, manuscript revision	Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
4698615	26708183	RC	2	design and conceptualization of the study, handling and treatment of tibialis anterior needle biopsies, muscle histopathological evaluation, morphometric analysis, data analysis and interpretation, manuscript drafting, final approval of the version to be published	design and conceptualization of the study, handling and treatment of tibialis anterior needle biopsies, muscle histopathological evaluation, morphometric analysis, data analysis and interpretation, manuscript drafting, final approval of the version to be published	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4698615	26708183	RV	2	contributed equally to this work|genetic analysis, data analysis and interpretation, manuscript revision	contributed equally to this work	-	-	NO
4698615	26708183	RV	2	contributed equally to this work|genetic analysis, data analysis and interpretation, manuscript revision	genetic analysis, data analysis and interpretation, manuscript revision	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Review & Editing	YES
4698615	26708183	SI	2	contributed equally to this work|biomolecular analysis, data analysis and interpretation, participating in drafting the manuscript	contributed equally to this work	-	-	NO
4698615	26708183	SI	2	contributed equally to this work|biomolecular analysis, data analysis and interpretation, participating in drafting the manuscript	biomolecular analysis, data analysis and interpretation, participating in drafting the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5845534	29559982	All authors	2	read and approved the final manuscript draft	read and approved the final manuscript draft	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5845534	29559982	DL	2	modified the manuscript	modified the manuscript	Wrote the paper	Writing - Review & Editing	YES
5845534	29559982	DM	2	modified the manuscript	modified the manuscript	Wrote the paper	Writing - Review & Editing	YES
5845534	29559982	FW	2	provided assistance in the abiotic stress pre-screening experiment	provided assistance in the abiotic stress pre-screening experiment	Performed the experiments	Investigation	YES
5845534	29559982	FZ	2	generated the transgenic materials	generated the transgenic materials	Performed the experiments	Investigation	YES
5845534	29559982	HW	2	provided assistance in the abiotic stress pre-screening experiment	provided assistance in the abiotic stress pre-screening experiment	Performed the experiments	Investigation	YES
5845534	29559982	LC	2	analyzed the data and edited the manuscript	analyzed the data and edited the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5845534	29559982	ML	2	designed the experiments|analyzed the data and edited the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5845534	29559982	ML	2	designed the experiments|analyzed the data and edited the manuscript	analyzed the data and edited the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5845534	29559982	SL	2	modified the manuscript	modified the manuscript	Wrote the paper	Writing - Review & Editing	YES
5845534	29559982	YG	2	generated the transgenic materials	generated the transgenic materials	Performed the experiments	Investigation	YES
5845534	29559982	YH	2	designed the experiments|performed the experiments and wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
5845534	29559982	YH	2	designed the experiments|performed the experiments and wrote the manuscript	performed the experiments and wrote the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5845534	29559982	YL	2	generated the transgenic materials	generated the transgenic materials	Performed the experiments	Investigation	YES
5845534	29559982	ZW	2	provided assistance in the abiotic stress pre-screening experiment	provided assistance in the abiotic stress pre-screening experiment	Performed the experiments	Investigation	YES
6270905	25322285	All authors	2	discussed and approved the final version	discussed and approved the final version	-	-	NO
6270905	25322285	Pham Thi Be	2	designed the research|performed the experimental work and analyzed data|wrote and edited the paper	designed the research	Conceived and designed the experiments	Methodology	YES
6270905	25322285	Pham Thi Be	2	designed the research|performed the experimental work and analyzed data|wrote and edited the paper	performed the experimental work and analyzed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270905	25322285	Pham Thi Be	2	designed the research|performed the experimental work and analyzed data|wrote and edited the paper	wrote and edited the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6270905	25322285	Shinkichi Tawata	2	designed the research|wrote and edited the paper	designed the research	Conceived and designed the experiments	Methodology	YES
6270905	25322285	Shinkichi Tawata	2	designed the research|wrote and edited the paper	wrote and edited the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6104406	30136217	ACP	2	revised the manuscript and supervised the experimental work	revised the manuscript and supervised the experimental work	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Review & Editing	YES
6104406	30136217	All authors	2	read and approved the final manuscript|agree with the publication and with the availability of data and material	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6104406	30136217	All authors	2	read and approved the final manuscript|agree with the publication and with the availability of data and material	agree with the publication and with the availability of data and material	-	-	NO
6104406	30136217	CS	2	revised the manuscript and supervised the experimental work	revised the manuscript and supervised the experimental work	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Review & Editing	YES
6104406	30136217	JF	2	gave several inputs on experimental procedures during the work	gave several inputs on experimental procedures during the work	Performed the experiments	Investigation	YES
6104406	30136217	JN	2	performed and interpreted the nmr spectra and participate on maldi-tof experiments	performed and interpreted the nmr spectra and participate on maldi-tof experiments	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6104406	30136217	JS	2	performed the experimental work and has written the first draft of the manuscript	performed the experimental work and has written the first draft of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6104406	30136217	QW	2	gave several inputs on experimental procedures during the work	gave several inputs on experimental procedures during the work	Performed the experiments	Investigation	YES
6104406	30136217	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5704593	29209502	All authors	2	participated in patient care	participated in patient care	Performed the experiments	Investigation	YES
5704593	29209502	YK	2	wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
2040197	17971879	AA	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2040197	17971879	AW	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2040197	17971879	AW	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2040197	17971879	AW	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2040197	17971879	DK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2040197	17971879	DK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2040197	17971879	DK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2040197	17971879	DK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2040197	17971879	DN	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2040197	17971879	DN	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2040197	17971879	LR	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2040197	17971879	MF	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2040197	17971879	MF	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2040197	17971879	MF	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2040197	17971879	MM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2040197	17971879	MM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2040197	17971879	MM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2040197	17971879	RD	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2040197	17971879	RD	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2040197	17971879	RD	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2040197	17971879	RD	PLoS5	Conceived and designed the experiments|Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3799496	24000153	AGD	PLoS52	analysed the data|contributed to part of the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
3799496	24000153	AGD	PLoS52	analysed the data|contributed to part of the manuscript	contributed to part of the manuscript	-	-	NO
3799496	24000153	CQ	PLoS52	helped with minigene experiments	helped with minigene experiments	Performed the experiments	Investigation	YES
3799496	24000153	DW	PLoS52	provided the clinical expertise|contributed to part of the manuscript	provided the clinical expertise	-	-	NO
3799496	24000153	DW	PLoS52	provided the clinical expertise|contributed to part of the manuscript	contributed to part of the manuscript	-	-	NO
3799496	24000153	HH	PLoS52	performed mutation screening	performed mutation screening	Performed the experiments	Investigation	YES
3799496	24000153	JM	PLoS52	performed par-clip data analysis	performed par-clip data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3799496	24000153	MJ	PLoS52	performed par-clip data analysis	performed par-clip data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3799496	24000153	ML	PLoS52	help with par-clip experiments	help with par-clip experiments	Performed the experiments	Investigation	YES
3799496	24000153	SF	PLoS52	performed par-clip data analysis	performed par-clip data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3799496	24000153	VK	PLoS52	performed mutation screening	performed mutation screening	Performed the experiments	Investigation	YES
3799496	24000153	WC	PLoS52	conceived and supervised the project|wrote the paper	conceived and supervised the project	Conceived and designed the experiments	Conceptualization|Supervision	YES
3799496	24000153	WC	PLoS52	conceived and supervised the project|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3799496	24000153	YH	PLoS52	conceived and supervised the project|contributed to part of the manuscript	conceived and supervised the project	Conceived and designed the experiments	Conceptualization|Supervision	YES
3799496	24000153	YH	PLoS52	conceived and supervised the project|contributed to part of the manuscript	contributed to part of the manuscript	-	-	NO
3799496	24000153	YM	PLoS52	helped with minigene experiments	helped with minigene experiments	Performed the experiments	Investigation	YES
3799496	24000153	YW	PLoS52	performed the experiments|contributed to part of the manuscript	performed the experiments	Performed the experiments	Investigation	YES
3799496	24000153	YW	PLoS52	performed the experiments|contributed to part of the manuscript	contributed to part of the manuscript	-	-	NO
3799496	24000153	YaM	PLoS52	help with par-clip experiments	help with par-clip experiments	Performed the experiments	Investigation	YES
3799496	24000153	YaW	PLoS52	helped with minigene experiments	helped with minigene experiments	Performed the experiments	Investigation	YES
5784067	29335371	All authors	2	participated in the conception and design of the study|commented on the first draft and contributed to the final draft	participated in the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5784067	29335371	All authors	2	participated in the conception and design of the study|commented on the first draft and contributed to the final draft	commented on the first draft and contributed to the final draft	Wrote the paper	Writing - Original Draft	YES
5784067	29335371	D.H.N.	2	collated the data and performed the standardized analyses on raw data|performed the analyses and wrote the first draft of the paper	collated the data and performed the standardized analyses on raw data	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5784067	29335371	D.H.N.	2	collated the data and performed the standardized analyses on raw data|performed the analyses and wrote the first draft of the paper	performed the analyses and wrote the first draft of the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5784067	29335371	H.F.	2	performed the analyses and wrote the first draft of the paper	performed the analyses and wrote the first draft of the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5784067	29335371	J.J.B.	2	collated the data and performed the standardized analyses on raw data|performed the analyses and wrote the first draft of the paper	collated the data and performed the standardized analyses on raw data	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5784067	29335371	J.J.B.	2	collated the data and performed the standardized analyses on raw data|performed the analyses and wrote the first draft of the paper	performed the analyses and wrote the first draft of the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5784067	29335371	J.P.M.	2	screened the literature for eligibility	screened the literature for eligibility	Performed the experiments	Investigation	YES
5784067	29335371	R.V.W.	2	screened the literature for eligibility|collated the data and performed the standardized analyses on raw data|performed the analyses and wrote the first draft of the paper	screened the literature for eligibility	Performed the experiments	Investigation	YES
5784067	29335371	R.V.W.	2	screened the literature for eligibility|collated the data and performed the standardized analyses on raw data|performed the analyses and wrote the first draft of the paper	collated the data and performed the standardized analyses on raw data	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5784067	29335371	R.V.W.	2	screened the literature for eligibility|collated the data and performed the standardized analyses on raw data|performed the analyses and wrote the first draft of the paper	performed the analyses and wrote the first draft of the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4418815	25938587	DX	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4418815	25938587	DX	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418815	25938587	EP	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418815	25938587	EP	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418815	25938587	HSW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418815	25938587	HSW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418815	25938587	HSW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418815	25938587	HSW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418815	25938587	KRB	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418815	25938587	KRB	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418815	25938587	RAL	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418815	25938587	SZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418815	25938587	SZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418815	25938587	SZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418815	25938587	SZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418815	25938587	SZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3913392	24511289	Gaibin Lian	2	contributed equally to this work	contributed equally to this work	-	-	NO
3913392	24511289	Zhiwen Ding	2	contributed equally to this work	contributed equally to this work	-	-	NO
5836831	29504899	AVO	2	interpreted the computer-based predictions in comparison with experimental data	interpreted the computer-based predictions in comparison with experimental data	Analyzed the data	Formal analysis	YES
5836831	29504899	All	2	the coauthors read and approved the final version of the manuscript	the coauthors read and approved the final version of the manuscript	-	-	NO
5836831	29504899	DAR	2	designed, developed, maintained, adapted, and tuned the software for sequence analysis	designed, developed, maintained, adapted, and tuned the software for sequence analysis	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
5836831	29504899	DAZ	2	conducted the in vitro experiments	conducted the in vitro experiments	Performed the experiments	Investigation	YES
5836831	29504899	EBS	2	conducted the in vitro experiments	conducted the in vitro experiments	Performed the experiments	Investigation	YES
5836831	29504899	EVK	2	conducted the ex vivo experiments	conducted the ex vivo experiments	Performed the experiments	Investigation	YES
5836831	29504899	IAD	2	conducted the in vitro experiments	conducted the in vitro experiments	Performed the experiments	Investigation	YES
5836831	29504899	IVC	2	analyzed data in silico	analyzed data in silico	Analyzed the data	Formal analysis	YES
5836831	29504899	LKS	2	conducted the in vitro experiments	conducted the in vitro experiments	Performed the experiments	Investigation	YES
5836831	29504899	LVO	2	interpreted the computer-based predictions in comparison with experimental data	interpreted the computer-based predictions in comparison with experimental data	Analyzed the data	Formal analysis	YES
5836831	29504899	MPP	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5836831	29504899	NAK	2	conceived of and supervised the study	conceived of and supervised the study	Conceived and designed the experiments	Conceptualization|Supervision	YES
5836831	29504899	OVA	2	conducted the in vitro experiments	conducted the in vitro experiments	Performed the experiments	Investigation	YES
5836831	29504899	PMP	2	designed, developed, maintained, adapted, and tuned the software for sequence analysis	designed, developed, maintained, adapted, and tuned the software for sequence analysis	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Software	YES
6270906	24914892	A. N. Diaz	2	tested the biological activity of the compounds and interpreted the results	tested the biological activity of the compounds and interpreted the results	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270906	24914892	Gaspar Diaz	2	conceived the concept, design of study, and wrote the article	conceived the concept, design of study, and wrote the article	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
4698616	26708184	all authors	2	contributed equally to this work and approved the version to be published	contributed equally to this work and approved the version to be published	-	-	NO
5845538	29559989	X-RZ	2	conducted the gene silencing analyses|carried out the gene expression, designed and analyzed all statistical data|prepared the manuscript	conducted the gene silencing analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5845538	29559989	X-RZ	2	conducted the gene silencing analyses|carried out the gene expression, designed and analyzed all statistical data|prepared the manuscript	carried out the gene expression, designed and analyzed all statistical data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5845538	29559989	X-RZ	2	conducted the gene silencing analyses|carried out the gene expression, designed and analyzed all statistical data|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5845538	29559989	X-ZC	2	conceived of the study, and participated in its design and coordination|prepared the manuscript	conceived of the study, and participated in its design and coordination	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
5845538	29559989	X-ZC	2	conceived of the study, and participated in its design and coordination|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5845538	29559989	Y-PX	2	carried out the gene expression, designed and analyzed all statistical data	carried out the gene expression, designed and analyzed all statistical data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5715543	29225888	AFS	2	contributed to bma samples analysis and to the interpretation of the data, critical revision of the manuscript, and final approval of the version to be published	contributed to bma samples analysis and to the interpretation of the data, critical revision of the manuscript, and final approval of the version to be published	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
5715543	29225888	AL	2	contributed to the interpretation of the data, critical revision of the manuscript, and final approval of the version to be published	contributed to the interpretation of the data, critical revision of the manuscript, and final approval of the version to be published	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
5715543	29225888	BP	2	contributed to statistical analysis and to the interpretation of the data, critical revision of the manuscript, and final approval of the version to be published	contributed to statistical analysis and to the interpretation of the data, critical revision of the manuscript, and final approval of the version to be published	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5715543	29225888	BS	2	are the guarantor of the paper and takes responsibility for the integrity of the work as a whole, from inception to the published article|contributed to the interpretation of the data, critical revision of the manuscript, and final approval of the version to be published	are the guarantor of the paper and takes responsibility for the integrity of the work as a whole, from inception to the published article	-	-	NO
5715543	29225888	BS	2	are the guarantor of the paper and takes responsibility for the integrity of the work as a whole, from inception to the published article|contributed to the interpretation of the data, critical revision of the manuscript, and final approval of the version to be published	contributed to the interpretation of the data, critical revision of the manuscript, and final approval of the version to be published	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
5715543	29225888	GM	2	contributed bma samples analysis and to the interpretation of the data, critical revision of the manuscript, and final approval of the version to be published	contributed bma samples analysis and to the interpretation of the data, critical revision of the manuscript, and final approval of the version to be published	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
5715543	29225888	LC	2	are the guarantor of the paper and takes responsibility for the integrity of the work as a whole, from inception to the published article	are the guarantor of the paper and takes responsibility for the integrity of the work as a whole, from inception to the published article	-	-	NO
2040198	17971880	JF	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2040198	17971880	JM	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2040198	17971880	JM	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2040198	17971880	LH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2040198	17971880	LH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2040198	17971880	LH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2040198	17971880	LH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2040198	17971880	VK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2040198	17971880	VK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2040198	17971880	VK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6104410	30136100	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6104410	30136100	MJK	2	helped with data analysis and manuscript preparation	helped with data analysis and manuscript preparation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6104410	30136100	SB	2	initiated the project and supervised the work	initiated the project and supervised the work	Conceived and designed the experiments	Conceptualization|Supervision	YES
4418816	25938445	HWY	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418816	25938445	J. Lee	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
3799497	23964012	CLA	2	assisted with experimental design	assisted with experimental design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3799497	23964012	DB	2	performed gfp transfection and analysis of pgc-1 in raw cells	performed gfp transfection and analysis of pgc-1 in raw cells	Performed the experiments	Investigation	YES
3799497	23964012	DJF	2	assisted ob wrote the manuscript with advice and	assisted ob wrote the manuscript with advice and	Wrote the paper	Writing - Original Draft	YES
3799497	23964012	DM	2	performed foam cell assays in raw macrophages and completed in vitro validation of pgc-1a and target genes	performed foam cell assays in raw macrophages and completed in vitro validation of pgc-1a and target genes	Performed the experiments	Investigation|Validation	YES
3799497	23964012	MdeG	2	performed all analysis of human tissue|performed aperio quantification of human tissue	performed all analysis of human tissue	Performed the experiments	Investigation	YES
3799497	23964012	MdeG	2	performed all analysis of human tissue|performed aperio quantification of human tissue	performed aperio quantification of human tissue	Performed the experiments	Investigation	YES
3799497	23964012	NL	2	performed foam cell assays in raw macrophages and completed in vitro validation of pgc-1a and target genes	performed foam cell assays in raw macrophages and completed in vitro validation of pgc-1a and target genes	Performed the experiments	Investigation|Validation	YES
3799497	23964012	OB	2	wrote the manuscript with advice and	wrote the manuscript with advice and	Wrote the paper	Writing - Original Draft	YES
3799497	23964012	SMcC	2	performed all analysis of human tissue	performed all analysis of human tissue	Performed the experiments	Investigation	YES
3799497	23964012	WJ	2	assisted with all imaging acquisition and microscopy	assisted with all imaging acquisition and microscopy	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
5836836	29504907	AAD	PLoS52	conceived and designed the work|analyzed the data|wrote the manuscript	conceived and designed the work	Conceived and designed the experiments	Conceptualization	YES
5836836	29504907	AAD	PLoS52	conceived and designed the work|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5836836	29504907	AAD	PLoS52	conceived and designed the work|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5836836	29504907	ADK	PLoS52	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5836836	29504907	AFS	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5836836	29504907	ARZ	PLoS52	conceived and designed the work|analyzed the data	conceived and designed the work	Conceived and designed the experiments	Conceptualization	YES
5836836	29504907	ARZ	PLoS52	conceived and designed the work|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5836836	29504907	AVK	PLoS52	conceived and designed the work|analyzed the data|wrote the manuscript	conceived and designed the work	Conceived and designed the experiments	Conceptualization	YES
5836836	29504907	AVK	PLoS52	conceived and designed the work|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5836836	29504907	AVK	PLoS52	conceived and designed the work|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5836836	29504907	AVS	PLoS52	conceived and designed the work|performed the experiments|analyzed the data|wrote the manuscript	conceived and designed the work	Conceived and designed the experiments	Conceptualization	YES
5836836	29504907	AVS	PLoS52	conceived and designed the work|performed the experiments|analyzed the data|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5836836	29504907	AVS	PLoS52	conceived and designed the work|performed the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5836836	29504907	AVS	PLoS52	conceived and designed the work|performed the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5836836	29504907	AYP	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5836836	29504907	BYA	PLoS52	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5836836	29504907	DSS	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5836836	29504907	DVS	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5836836	29504907	EAP	PLoS52	conceived and designed the work|performed the experiments|analyzed the data|wrote the manuscript	conceived and designed the work	Conceived and designed the experiments	Conceptualization	YES
5836836	29504907	EAP	PLoS52	conceived and designed the work|performed the experiments|analyzed the data|wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5836836	29504907	EAP	PLoS52	conceived and designed the work|performed the experiments|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5836836	29504907	EAP	PLoS52	conceived and designed the work|performed the experiments|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5836836	29504907	ENL	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5836836	29504907	GSK	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5836836	29504907	ISA	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5836836	29504907	KMK	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5836836	29504907	KMN	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5836836	29504907	MAC	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5836836	29504907	MSF	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5836836	29504907	MSF	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5836836	29504907	MVK	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5836836	29504907	NNV	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5836836	29504907	NVK	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5836836	29504907	NVM	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5836836	29504907	SLK	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
4698617	26708185	AC	2	study concept and design|critical revision of the manuscript for important intellectual content|samples collection	study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4698617	26708185	AC	2	study concept and design|critical revision of the manuscript for important intellectual content|samples collection	critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4698617	26708185	AC	2	study concept and design|critical revision of the manuscript for important intellectual content|samples collection	samples collection	Performed the experiments	Investigation	YES
4698617	26708185	AZ	2	immunohistochemical and data analysis	immunohistochemical and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4698617	26708185	CA	2	immunohistochemical and data analysis	immunohistochemical and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4698617	26708185	CL	2	immunohistochemical and data analysis	immunohistochemical and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4698617	26708185	DM	2	study concept and design|immunohistochemical and data analysis|manuscript drafting, interpretation of data, statistical analysis|critical revision of the manuscript for important intellectual content	study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4698617	26708185	DM	2	study concept and design|immunohistochemical and data analysis|manuscript drafting, interpretation of data, statistical analysis|critical revision of the manuscript for important intellectual content	immunohistochemical and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4698617	26708185	DM	2	study concept and design|immunohistochemical and data analysis|manuscript drafting, interpretation of data, statistical analysis|critical revision of the manuscript for important intellectual content	manuscript drafting, interpretation of data, statistical analysis	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4698617	26708185	DM	2	study concept and design|immunohistochemical and data analysis|manuscript drafting, interpretation of data, statistical analysis|critical revision of the manuscript for important intellectual content	critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4698617	26708185	EA	2	study concept and design|manuscript drafting, interpretation of data, statistical analysis|critical revision of the manuscript for important intellectual content|statistical analysis	study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4698617	26708185	EA	2	study concept and design|manuscript drafting, interpretation of data, statistical analysis|critical revision of the manuscript for important intellectual content|statistical analysis	manuscript drafting, interpretation of data, statistical analysis	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4698617	26708185	EA	2	study concept and design|manuscript drafting, interpretation of data, statistical analysis|critical revision of the manuscript for important intellectual content|statistical analysis	critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4698617	26708185	EA	2	study concept and design|manuscript drafting, interpretation of data, statistical analysis|critical revision of the manuscript for important intellectual content|statistical analysis	statistical analysis	Analyzed the data	Formal analysis	YES
4698617	26708185	GG	2	study concept and design|immunohistochemical and data analysis|manuscript drafting, interpretation of data, statistical analysis|samples collection|histopathologic analysis	study concept and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4698617	26708185	GG	2	study concept and design|immunohistochemical and data analysis|manuscript drafting, interpretation of data, statistical analysis|samples collection|histopathologic analysis	immunohistochemical and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4698617	26708185	GG	2	study concept and design|immunohistochemical and data analysis|manuscript drafting, interpretation of data, statistical analysis|samples collection|histopathologic analysis	manuscript drafting, interpretation of data, statistical analysis	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4698617	26708185	GG	2	study concept and design|immunohistochemical and data analysis|manuscript drafting, interpretation of data, statistical analysis|samples collection|histopathologic analysis	samples collection	Performed the experiments	Investigation	YES
4698617	26708185	GG	2	study concept and design|immunohistochemical and data analysis|manuscript drafting, interpretation of data, statistical analysis|samples collection|histopathologic analysis	histopathologic analysis	Performed the experiments	Investigation	YES
4698617	26708185	GT	2	immunohistochemical and data analysis	immunohistochemical and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4698617	26708185	MC	2	critical revision of the manuscript for important intellectual content	critical revision of the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
4698617	26708185	TL	2	samples collection	samples collection	Performed the experiments	Investigation	YES
6270907	25329869	Lin-Lin Lu	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
6270907	25329869	Ling Ye	PLoS5	Conceived of and designed the experiments|Wrote the paper	Conceived of and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6270907	25329869	Ling Ye	PLoS5	Conceived of and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270907	25329869	Pei-Min Dai	PLoS5	Conceived of and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived of and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6270907	25329869	Pei-Min Dai	PLoS5	Conceived of and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
6270907	25329869	Pei-Min Dai	PLoS5	Conceived of and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
6270907	25329869	Pei-Min Dai	PLoS5	Conceived of and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270907	25329869	Qiang Li	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
6270907	25329869	Shan Zeng	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
6270907	25329869	Shan Zeng	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
6270907	25329869	Ying Wang	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
6270907	25329869	Ying Wang	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
6270907	25329869	Ying Wang	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270907	25329869	Zhi-Jie Zheng	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
6270907	25329869	Zhi-Jie Zheng	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
6270907	25329869	Zhong-Qiu Liu	PLoS5	Conceived of and designed the experiments|Wrote the paper	Conceived of and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6270907	25329869	Zhong-Qiu Liu	PLoS5	Conceived of and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5845638	29559986	FB	2	developed the bioinformatics tools to identify the polymorphisms on the magic parental lines	developed the bioinformatics tools to identify the polymorphisms on the magic parental lines	Performed the experiments	Formal analysis|Investigation	YES
5845638	29559986	ID	2	who conducted the statistical analyses and the redaction of the manuscript	who conducted the statistical analyses and the redaction of the manuscript	Analyzed the data	Formal analysis	YES
5845638	29559986	LP	2	reviewed the manuscript and shared a part of the script for qtl mapping analysis	reviewed the manuscript and shared a part of the script for qtl mapping analysis	Wrote the paper	Writing - Review & Editing	YES
5845638	29559986	MC	2	supervised all the process of this work, constructed the experimental design and monitored the redaction of the article	supervised all the process of this work, constructed the experimental design and monitored the redaction of the article	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology|Supervision	YES
5738213	29276608	DT	2	provided medicine for the patient|wrote the manuscript as corresponding authors	provided medicine for the patient	-	-	NO
5738213	29276608	DT	2	provided medicine for the patient|wrote the manuscript as corresponding authors	wrote the manuscript as corresponding authors	Wrote the paper	Writing - Original Draft	YES
5738213	29276608	HG	2	provided medicine for the patient|wrote the manuscript as corresponding authors	provided medicine for the patient	-	-	NO
5738213	29276608	HG	2	provided medicine for the patient|wrote the manuscript as corresponding authors	wrote the manuscript as corresponding authors	Wrote the paper	Writing - Original Draft	YES
5738213	29276608	JZ	2	provided medicine for the patient|wrote the manuscript	provided medicine for the patient	-	-	NO
5738213	29276608	JZ	2	provided medicine for the patient|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5738213	29276608	NB	2	provided medicine for the patient|wrote the manuscript as corresponding authors	provided medicine for the patient	-	-	NO
5738213	29276608	NB	2	provided medicine for the patient|wrote the manuscript as corresponding authors	wrote the manuscript as corresponding authors	Wrote the paper	Writing - Original Draft	YES
5738213	29276608	OL	2	provided medicine for the patient|wrote the manuscript as corresponding authors	provided medicine for the patient	-	-	NO
5738213	29276608	OL	2	provided medicine for the patient|wrote the manuscript as corresponding authors	wrote the manuscript as corresponding authors	Wrote the paper	Writing - Original Draft	YES
5738213	29276608	P-YD	2	provided medicine for the patient|wrote the manuscript	provided medicine for the patient	-	-	NO
5738213	29276608	P-YD	2	provided medicine for the patient|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6104463	30136000	AK	2	participated in the interpretation of data and performed the measurement	participated in the interpretation of data and performed the measurement	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6104463	30136000	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6104463	30136000	CN	2	participated in the design and interpretation of the study and helped to draft the manuscript	participated in the design and interpretation of the study and helped to draft the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
6104463	30136000	KK	2	participated in the interpretation of data and performed the measurement	participated in the interpretation of data and performed the measurement	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6104463	30136000	LH	2	conceived of the study, participated in its design and coordinated and drafted the manuscript and participated in the interpretation and measurement of data	conceived of the study, participated in its design and coordinated and drafted the manuscript and participated in the interpretation and measurement of data	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Project administration|Writing - Original Draft	YES
6104463	30136000	RK	2	participated in the design of the study and helped to draft the manuscript	participated in the design of the study and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
2040199	17971871	AC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
2040199	17971871	CB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2040199	17971871	CB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2040199	17971871	CB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2040199	17971871	CB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2040199	17971871	UC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2040199	17971871	UC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2040199	17971871	UC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2040199	17971871	UC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2040199	17971871	WG	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418817	25938806	AGP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418817	25938806	AGP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418817	25938806	AGP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418817	25938806	AGT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418817	25938806	AGT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418817	25938806	AGT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418817	25938806	AGT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418817	25938806	AGT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418817	25938806	EM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418817	25938806	EM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418817	25938806	EM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418817	25938806	EM	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418817	25938806	FAG	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418817	25938806	HRB	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418817	25938806	HRB	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418817	25938806	VAG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418817	25938806	VAG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418817	25938806	VAG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418817	25938806	VAG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4698618	26708186	All authors	2	approve the version to be published	approve the version to be published	-	-	NO
4698618	26708186	FA	2	immunofluorescence experiments, analysis and discussion of the data|manuscript writing	immunofluorescence experiments, analysis and discussion of the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4698618	26708186	FA	2	immunofluorescence experiments, analysis and discussion of the data|manuscript writing	manuscript writing	Wrote the paper	Writing - Original Draft	YES
4698618	26708186	MGB	2	method design, analysis and interpretation of results|manuscript writing	method design, analysis and interpretation of results	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis	YES
4698618	26708186	MGB	2	method design, analysis and interpretation of results|manuscript writing	manuscript writing	Wrote the paper	Writing - Original Draft	YES
4698618	26708186	MM	2	electron microscopy experiments|manuscript writing	electron microscopy experiments	Performed the experiments	Investigation	YES
4698618	26708186	MM	2	electron microscopy experiments|manuscript writing	manuscript writing	Wrote the paper	Writing - Original Draft	YES
4698618	26708186	PV	2	cell culture	cell culture	Performed the experiments	Investigation	YES
5836839	29504892	IIT	2	contributed to the interpretation of results, and were involved in manuscript editing|designed and coordinated the study	contributed to the interpretation of results, and were involved in manuscript editing	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5836839	29504892	IIT	2	contributed to the interpretation of results, and were involved in manuscript editing|designed and coordinated the study	designed and coordinated the study	Conceived and designed the experiments	Methodology|Project administration	YES
5836839	29504892	PSV	2	performed bioinformatics calculations|contributed to the interpretation of results, and were involved in manuscript editing	performed bioinformatics calculations	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5836839	29504892	PSV	2	performed bioinformatics calculations|contributed to the interpretation of results, and were involved in manuscript editing	contributed to the interpretation of results, and were involved in manuscript editing	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4275150	25489925	J.C.H.	2	contributed equally	contributed equally	-	-	NO
4275150	25489925	S.E.S.	2	contributed equally	contributed equally	-	-	NO
5738227	29276607	AB	2	were involved in the data acquisition and revising the manuscript	were involved in the data acquisition and revising the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5738227	29276607	BN	2	were involved in the conception/design, data acquisition, analysis/interpretation, and drafting/revising the manuscript	were involved in the conception/design, data acquisition, analysis/interpretation, and drafting/revising the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5738227	29276607	CLT	2	were involved in the conception/design/data acquisition, analysis, and drafting/revising the manuscript	were involved in the conception/design/data acquisition, analysis, and drafting/revising the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5738227	29276607	DBT	2	were involved in the data acquisition and revising the manuscript	were involved in the data acquisition and revising the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5738227	29276607	DPK	2	were involved in the data acquisition	were involved in the data acquisition	Performed the experiments	Investigation	YES
5738227	29276607	DQT	2	were involved in data acquisition|contributed to data collection	were involved in data acquisition	Performed the experiments	Investigation	YES
5738227	29276607	DQT	2	were involved in data acquisition|contributed to data collection	contributed to data collection	Performed the experiments	Investigation	YES
5738227	29276607	DSB	2	were involved in the conception/design and data acquisition	were involved in the conception/design and data acquisition	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5738227	29276607	DTT	2	were involved in data acquisition|contributed to data collection	were involved in data acquisition	Performed the experiments	Investigation	YES
5738227	29276607	DTT	2	were involved in data acquisition|contributed to data collection	contributed to data collection	Performed the experiments	Investigation	YES
5738227	29276607	DXC	2	were involved in data acquisition|contributed to data collection	were involved in data acquisition	Performed the experiments	Investigation	YES
5738227	29276607	DXC	2	were involved in data acquisition|contributed to data collection	contributed to data collection	Performed the experiments	Investigation	YES
5738227	29276607	DZC	2	were involved in the conception/design and data acquisition	were involved in the conception/design and data acquisition	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5738227	29276607	GET	2	were involved in the conception/design and drafting/revising the manuscript	were involved in the conception/design and drafting/revising the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
5738227	29276607	GQT	2	were involved in the data acquisition	were involved in the data acquisition	Performed the experiments	Investigation	YES
5738227	29276607	GTA	2	were involved in the data acquisition	were involved in the data acquisition	Performed the experiments	Investigation	YES
5738227	29276607	HFM	2	was involved in conception/design of the study	was involved in conception/design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5738227	29276607	HH	2	were involved in the conception/design	were involved in the conception/design	Conceived and designed the experiments	Conceptualization	YES
5738227	29276607	HL	2	were involved in the data acquisition	were involved in the data acquisition	Performed the experiments	Investigation	YES
5738227	29276607	HNMV	2	were involved in the data acquisition	were involved in the data acquisition	Performed the experiments	Investigation	YES
5738227	29276607	HRVD	2	were involved in the conception/design/data acquisition, analysis, and drafting/revising the manuscript	were involved in the conception/design/data acquisition, analysis, and drafting/revising the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5738227	29276607	HRW	2	were involved in the conception/design/data acquisition, analysis, and drafting/revising the manuscript	were involved in the conception/design/data acquisition, analysis, and drafting/revising the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5738227	29276607	HSB	2	were involved in data acquisition|contributed to data collection	were involved in data acquisition	Performed the experiments	Investigation	YES
5738227	29276607	HSB	2	were involved in data acquisition|contributed to data collection	contributed to data collection	Performed the experiments	Investigation	YES
5738227	29276607	HTL	2	were involved in the conception/design and data acquisition	were involved in the conception/design and data acquisition	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5738227	29276607	JC	2	were involved in the conception/design and data acquisition	were involved in the conception/design and data acquisition	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5738227	29276607	LMY	2	were involved in the conception/design and data acquisition	were involved in the conception/design and data acquisition	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5738227	29276607	LTDT	2	were involved in the data acquisition	were involved in the data acquisition	Performed the experiments	Investigation	YES
5738227	29276607	MHM	2	were involved in the conception/design and data acquisition	were involved in the conception/design and data acquisition	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5738227	29276607	ML	2	were involved in the conception/design and drafting/revising the manuscript	were involved in the conception/design and drafting/revising the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
5738227	29276607	NGB	2	were involved in the conception/design and data acquisition	were involved in the conception/design and data acquisition	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5738227	29276607	NHAD	2	were involved in the conception/design, data acquisition, and analysis/interpretation	were involved in the conception/design, data acquisition, and analysis/interpretation	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation	YES
5738227	29276607	NHH	2	were involved in the conception/design	were involved in the conception/design	Conceived and designed the experiments	Conceptualization	YES
5738227	29276607	NTHM	2	were involved in the conception/design, data acquisition, and analysis/interpretation	were involved in the conception/design, data acquisition, and analysis/interpretation	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation	YES
5738227	29276607	NTT	2	were involved in the data acquisition	were involved in the data acquisition	Performed the experiments	Investigation	YES
5738227	29276607	NVH	2	were involved in the conception/design and data acquisition	were involved in the conception/design and data acquisition	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5738227	29276607	NVK	2	were involved in the conception/design	were involved in the conception/design	Conceived and designed the experiments	Conceptualization	YES
5738227	29276607	NVVC	2	were involved in the conception/design	were involved in the conception/design	Conceived and designed the experiments	Conceptualization	YES
5738227	29276607	QDD	2	were involved in the conception/design and drafting/revising the manuscript	were involved in the conception/design and drafting/revising the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
5738227	29276607	RBG	2	was involved in the data analysis/interpretation and drafting/ revising the manuscript	was involved in the data analysis/interpretation and drafting/ revising the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5738227	29276607	TNQ	2	were involved in the data acquisition	were involved in the data acquisition	Performed the experiments	Investigation	YES
5738227	29276607	VDP	2	were involved in the conception/design, data acquisition, analysis/interpretation, and drafting/revising the manuscript	were involved in the conception/design, data acquisition, analysis/interpretation, and drafting/revising the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
5845667	29559992	BA	2	performed the research	performed the research	Performed the experiments	Investigation	YES
5845667	29559992	CQZ	2	performed the research|analyzed the data and wrote the draft|designed the research	performed the research	Performed the experiments	Investigation	YES
5845667	29559992	CQZ	2	performed the research|analyzed the data and wrote the draft|designed the research	analyzed the data and wrote the draft	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5845667	29559992	CQZ	2	performed the research|analyzed the data and wrote the draft|designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
5845667	29559992	CZ	2	revised the article	revised the article	Wrote the paper	Writing - Review & Editing	YES
5845667	29559992	HS	2	revised the article	revised the article	Wrote the paper	Writing - Review & Editing	YES
5845667	29559992	JZ	2	performed the research	performed the research	Performed the experiments	Investigation	YES
5845667	29559992	LS	2	performed the research	performed the research	Performed the experiments	Investigation	YES
5845667	29559992	LZ	2	performed the research	performed the research	Performed the experiments	Investigation	YES
5845667	29559992	QJ	2	designed the research|wrote the article	designed the research	Conceived and designed the experiments	Methodology	YES
5845667	29559992	QJ	2	designed the research|wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
5845667	29559992	WH	2	revised the article	revised the article	Wrote the paper	Writing - Review & Editing	YES
5845667	29559992	XC	2	designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
5845667	29559992	ZB	2	revised the article	revised the article	Wrote the paper	Writing - Review & Editing	YES
2040200	17971862	CW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
2040200	17971862	HW	PLoS5	Contributed reagents and intellectual support	Contributed reagents and intellectual support	Contributed reagents/materials/analysis tools	Resources	YES
2040200	17971862	KS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2040200	17971862	KS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2040200	17971862	KS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2040200	17971862	KS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2040200	17971862	KS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6104467	30136189	AK	2	provided scientific support	provided scientific support	-	-	NO
6104467	30136189	All authors	2	have verified the manuscript|read and approved the final manuscript	have verified the manuscript	Performed the experiments	Validation	YES
6104467	30136189	All authors	2	have verified the manuscript|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6104467	30136189	HM	2	helped with the experimentation	helped with the experimentation	Performed the experiments	Investigation	YES
6104467	30136189	MA	2	designed, supervised and provided technical expertise to the project	designed, supervised and provided technical expertise to the project	Conceived and designed the experiments	Methodology|Supervision	YES
6104467	30136189	MAM	2	provided fermentation advice	provided fermentation advice	Performed the experiments	Investigation	YES
6104467	30136189	NNK	2	carried out the experiments and drafted the paper	carried out the experiments and drafted the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6104467	30136189	PKP	2	designed, supervised and provided technical expertise to the project	designed, supervised and provided technical expertise to the project	Conceived and designed the experiments	Methodology|Supervision	YES
6104467	30136189	RS	2	helped with the experimentation	helped with the experimentation	Performed the experiments	Investigation	YES
6104467	30136189	The authors	2	are thankful to the tehran university of medical sciences core research facility for providing the fermentation equipment and support materials|declare that they have no competing interests	are thankful to the tehran university of medical sciences core research facility for providing the fermentation equipment and support materials	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
6104467	30136189	The authors	2	are thankful to the tehran university of medical sciences core research facility for providing the fermentation equipment and support materials|declare that they have no competing interests	declare that they have no competing interests	-	-	NO
4418818	25938586	AEH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418818	25938586	AEH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418818	25938586	AEH	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418818	25938586	JJF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418818	25938586	JJF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418818	25938586	JJF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418818	25938586	JJF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270909	25529017	A.P.	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270909	25529017	R.F.	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5845668	29559985	All authors	2	revised the draft and approved the final manuscript	revised the draft and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5836841	29504893	FN	2	conceived and constructed the method, developed software, conducted numerical experiments and wrote the paper	conceived and constructed the method, developed software, conducted numerical experiments and wrote the paper	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Software|Writing - Original Draft	YES
5836841	29504893	IA	2	reviewed the statistical methods and the paper	reviewed the statistical methods and the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5836841	29504893	MG	2	supported computer cluster testing	supported computer cluster testing	Performed the experiments	Formal analysis|Investigation	YES
5836841	29504893	NB	2	reviewed the paper	reviewed the paper	Wrote the paper	Writing - Review & Editing	YES
5836841	29504893	YO	2	organized computational experiments and specified the paper	organized computational experiments and specified the paper	-	Formal analysis	YES
4275151	25494235	W.X.	2	contributed equally	contributed equally	-	-	NO
4275151	25494235	Y.Z.	2	contributed equally	contributed equally	-	-	NO
5740836	29299312	GHK	2	performed the animal experiments|contributed to the data analysis|contributed to the data interpretation|contributed to the data collection|completed the manuscript writing	performed the animal experiments	Performed the experiments	Investigation	YES
5740836	29299312	GHK	2	performed the animal experiments|contributed to the data analysis|contributed to the data interpretation|contributed to the data collection|completed the manuscript writing	contributed to the data analysis	Analyzed the data	Formal analysis	YES
5740836	29299312	GHK	2	performed the animal experiments|contributed to the data analysis|contributed to the data interpretation|contributed to the data collection|completed the manuscript writing	contributed to the data interpretation	Analyzed the data	Formal analysis	YES
5740836	29299312	GHK	2	performed the animal experiments|contributed to the data analysis|contributed to the data interpretation|contributed to the data collection|completed the manuscript writing	contributed to the data collection	Performed the experiments	Investigation	YES
5740836	29299312	GHK	2	performed the animal experiments|contributed to the data analysis|contributed to the data interpretation|contributed to the data collection|completed the manuscript writing	completed the manuscript writing	Wrote the paper	Writing - Original Draft	YES
5740836	29299312	HIK	2	contributed to the literature search	contributed to the literature search	-	Formal analysis	YES
5740836	29299312	HK	2	provided the critical revisions to the manuscript	provided the critical revisions to the manuscript	Wrote the paper	Writing - Review & Editing	YES
5740836	29299312	HY	2	performed the animal experiments|contributed to the data collection	performed the animal experiments	Performed the experiments	Investigation	YES
5740836	29299312	HY	2	performed the animal experiments|contributed to the data collection	contributed to the data collection	Performed the experiments	Investigation	YES
5740836	29299312	IK	2	performed the animal experiments	performed the animal experiments	Performed the experiments	Investigation	YES
5740836	29299312	KCC	2	contributed to the data analysis|contributed to the data interpretation	contributed to the data analysis	Analyzed the data	Formal analysis	YES
5740836	29299312	KCC	2	contributed to the data analysis|contributed to the data interpretation	contributed to the data interpretation	Analyzed the data	Formal analysis	YES
5740836	29299312	KHK	2	provided the critical revisions to the manuscript	provided the critical revisions to the manuscript	Wrote the paper	Writing - Review & Editing	YES
5740836	29299312	KHL	2	provided the critical revisions to the manuscript	provided the critical revisions to the manuscript	Wrote the paper	Writing - Review & Editing	YES
5740836	29299312	OHK	2	performed the animal experiments|contributed to the data collection	performed the animal experiments	Performed the experiments	Investigation	YES
5740836	29299312	OHK	2	performed the animal experiments|contributed to the data collection	contributed to the data collection	Performed the experiments	Investigation	YES
5740836	29299312	SOH	2	contributed to the data interpretation|designed and conceptualized the study|completed the manuscript writing	contributed to the data interpretation	Analyzed the data	Formal analysis	YES
5740836	29299312	SOH	2	contributed to the data interpretation|designed and conceptualized the study|completed the manuscript writing	designed and conceptualized the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5740836	29299312	SOH	2	contributed to the data interpretation|designed and conceptualized the study|completed the manuscript writing	completed the manuscript writing	Wrote the paper	Writing - Original Draft	YES
5740836	29299312	YSC	2	performed the animal experiments|contributed to the data collection	performed the animal experiments	Performed the experiments	Investigation	YES
5740836	29299312	YSC	2	performed the animal experiments|contributed to the data collection	contributed to the data collection	Performed the experiments	Investigation	YES
5740836	29299312	YSL	2	performed the animal experiments|contributed to the data collection	performed the animal experiments	Performed the experiments	Investigation	YES
5740836	29299312	YSL	2	performed the animal experiments|contributed to the data collection	contributed to the data collection	Performed the experiments	Investigation	YES
4670907	26682220	Cheng Ma	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
4670907	26682220	Jin Li	2	contributed equally to this paper	contributed equally to this paper	-	-	NO
2040201	17971874	BG	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2040201	17971874	BG	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2040201	17971874	MW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2040201	17971874	MW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2040201	17971874	MW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2040201	17971874	MW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2040201	17971874	MW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5784074	29335381	C.B.	2	assisted with the literature review and provided editorial assistance	assisted with the literature review and provided editorial assistance	-	Formal analysis	YES
5784074	29335381	K.d.P.	2	assisted with the literature review and provided editorial assistance	assisted with the literature review and provided editorial assistance	-	Formal analysis	YES
5784074	29335381	P.D.W.	2	developed the concepts, reviewed the literature, the manuscript and provided final editorial oversight	developed the concepts, reviewed the literature, the manuscript and provided final editorial oversight	Conceived and designed the experiments|Wrote the paper	Conceptualization|Formal analysis|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
5784074	29335381	S.E.	2	developed the concepts, reviewed the literature, the manuscript and provided final editorial oversight	developed the concepts, reviewed the literature, the manuscript and provided final editorial oversight	Conceived and designed the experiments|Wrote the paper	Conceptualization|Formal analysis|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
6270910	24962387	Bruno Mezzetti	PLoS52	contributed reagents/materials/analysis tools|contributed reagents/materials/analysis tools	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
6270910	24962387	Bruno Mezzetti	PLoS52	contributed reagents/materials/analysis tools|contributed reagents/materials/analysis tools	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
6270910	24962387	Celestino Santos-Buelga	PLoS52	contributed reagents/materials/analysis tools	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
6270910	24962387	Francesca Giampieri	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270910	24962387	Jose M. Alvarez-Suarez	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270910	24962387	Maurizio Battino	PLoS52	contributed reagents/materials/analysis tools	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
6270910	24962387	Stefano Bompadre	PLoS52	contributed reagents/materials/analysis tools	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5845686	29559988	AvZ	CRediT	Conceptualization|Methodology|Investigation|Formal analysis|Visualization|Writing - original draft|Writing - review and editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
5845686	29559988	AvZ	CRediT	Conceptualization|Methodology|Investigation|Formal analysis|Visualization|Writing - original draft|Writing - review and editing	Methodology	Performed the experiments	Methodology	YES
5845686	29559988	AvZ	CRediT	Conceptualization|Methodology|Investigation|Formal analysis|Visualization|Writing - original draft|Writing - review and editing	Investigation	Performed the experiments	Investigation	YES
5845686	29559988	AvZ	CRediT	Conceptualization|Methodology|Investigation|Formal analysis|Visualization|Writing - original draft|Writing - review and editing	Formal analysis	Analyzed the data	Formal analysis	YES
5845686	29559988	AvZ	CRediT	Conceptualization|Methodology|Investigation|Formal analysis|Visualization|Writing - original draft|Writing - review and editing	Visualization	Analyzed the data	Visualization	YES
5845686	29559988	AvZ	CRediT	Conceptualization|Methodology|Investigation|Formal analysis|Visualization|Writing - original draft|Writing - review and editing	Writing - original draft	Wrote the paper	Writing - Original Draft	YES
5845686	29559988	AvZ	CRediT	Conceptualization|Methodology|Investigation|Formal analysis|Visualization|Writing - original draft|Writing - review and editing	Writing - review and editing	Wrote the paper	Writing - Review & Editing	YES
5845686	29559988	EF	CRediT	Investigation|Formal analysis	Investigation	Performed the experiments	Investigation	YES
5845686	29559988	EF	CRediT	Investigation|Formal analysis	Formal analysis	Analyzed the data	Formal analysis	YES
5845686	29559988	FB	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
5845686	29559988	LR	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
5845686	29559988	MH	CRediT	Methodology|Investigation	Methodology	Performed the experiments	Methodology	YES
5845686	29559988	MH	CRediT	Methodology|Investigation	Investigation	Performed the experiments	Investigation	YES
5845686	29559988	MSK	CRediT	Investigation	Investigation	Performed the experiments	Investigation	YES
5845686	29559988	RG	CRediT	Conceptualization|Writing - review and editing|Funding acquisition|Supervision	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
5845686	29559988	RG	CRediT	Conceptualization|Writing - review and editing|Funding acquisition|Supervision	Writing - review and editing	Wrote the paper	Writing - Review & Editing	YES
5845686	29559988	RG	CRediT	Conceptualization|Writing - review and editing|Funding acquisition|Supervision	Funding acquisition	-	Funding acquisition	YES
5845686	29559988	RG	CRediT	Conceptualization|Writing - review and editing|Funding acquisition|Supervision	Supervision	-	Supervision	YES
5845686	29559988	SL	CRediT	Methodology|Investigation	Methodology	Performed the experiments	Methodology	YES
5845686	29559988	SL	CRediT	Methodology|Investigation	Investigation	Performed the experiments	Investigation	YES
5845686	29559988	TB	CRediT	Funding acquisition	Funding acquisition	-	Funding acquisition	YES
5845686	29559988	TW	CRediT	Investigation|Formal analysis	Investigation	Performed the experiments	Investigation	YES
5845686	29559988	TW	CRediT	Investigation|Formal analysis	Formal analysis	Analyzed the data	Formal analysis	YES
5845686	29559988	WK	CRediT	Methodology|Investigation	Methodology	Performed the experiments	Methodology	YES
5845686	29559988	WK	CRediT	Methodology|Investigation	Investigation	Performed the experiments	Investigation	YES
6109036	30143892	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6109036	30143892	PI	2	of all grants, design experiments and draft the manuscript	of all grants, design experiments and draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4418819	25938548	DPB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418819	25938548	DPB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418819	25938548	DPB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418819	25938548	DPB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418819	25938548	FJS	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418819	25938548	HCM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418819	25938548	HCM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4418819	25938548	HCM	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418819	25938548	KWC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418819	25938548	KWC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418819	25938548	KWC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418819	25938548	KWC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418819	25938548	KWC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418819	25938548	MNC	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418819	25938548	MNC	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418819	25938548	MNC	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418819	25938548	MNC	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418819	25938548	NHdK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418819	25938548	NHdK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4418819	25938548	NHdK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418819	25938548	PLT	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5838959	29510665	AM	2	performed the database work and data analyses presented in fig	performed the database work and data analyses presented in fig	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Software	YES
5838959	29510665	COD	2	conceived and supervised the study	conceived and supervised the study	Conceived and designed the experiments	Conceptualization|Supervision	YES
5838959	29510665	DST	2	performed the database work, data analysis, experimental validation work and made all the figures|wrote and edited the manuscript	performed the database work, data analysis, experimental validation work and made all the figures	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Software|Validation|Visualization	YES
5838959	29510665	DST	2	performed the database work, data analysis, experimental validation work and made all the figures|wrote and edited the manuscript	wrote and edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5838959	29510665	GL	2	contributed to the database work and data analysis presented in fig|performed and analyzed all the protein work	contributed to the database work and data analysis presented in fig	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Software	YES
5838959	29510665	GL	2	contributed to the database work and data analysis presented in fig|performed and analyzed all the protein work	performed and analyzed all the protein work	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5838959	29510665	JK	2	conceived and supervised the study|wrote and edited the manuscript	conceived and supervised the study	Conceived and designed the experiments	Conceptualization|Supervision	YES
5838959	29510665	JK	2	conceived and supervised the study|wrote and edited the manuscript	wrote and edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5838959	29510665	PS	2	conceived and supervised the study|wrote and edited the manuscript	conceived and supervised the study	Conceived and designed the experiments	Conceptualization|Supervision	YES
5838959	29510665	PS	2	conceived and supervised the study|wrote and edited the manuscript	wrote and edited the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5838959	29510665	SM	2	performed and analyzed all the protein work	performed and analyzed all the protein work	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4800245	26972709	All	2	the listed authors have participated actively in the study and all meet the requirements of the authorship	the listed authors have participated actively in the study and all meet the requirements of the authorship	-	-	NO
4800245	26972709	JC	2	statistical analysis	statistical analysis	Analyzed the data	Formal analysis	YES
4800245	26972709	JLai	2	literature searches and analyses	literature searches and analyses	Analyzed the data	Formal analysis	YES
4800245	26972709	JLiang	2	statistical analysis	statistical analysis	Analyzed the data	Formal analysis	YES
4800245	26972709	KZ	2	study design, protocol writing	study design, protocol writing	Conceived and designed the experiments|Wrote the paper	Methodology	YES
4800245	26972709	LH	2	performed research/study	performed research/study	Performed the experiments	Investigation	YES
4800245	26972709	LL	2	contributed important reagents	contributed important reagents	Contributed reagents/materials/analysis tools	Resources	YES
4800245	26972709	LY	2	literature searches and analyses	literature searches and analyses	Analyzed the data	Formal analysis	YES
4800245	26972709	WC	2	writing of the manuscript first draft|performed research/study	writing of the manuscript first draft	Wrote the paper	Writing - Original Draft	YES
4800245	26972709	WC	2	writing of the manuscript first draft|performed research/study	performed research/study	Performed the experiments	Investigation	YES
2040202	17971875	AP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
2040202	17971875	AP	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2040202	17971875	BC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
2040202	17971875	BC	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2040202	17971875	DH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2040202	17971875	DH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2040202	17971875	DH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2040202	17971875	MY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2040202	17971875	MY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2040202	17971875	MY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2040202	17971875	MY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2040202	17971875	VG	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2040202	17971875	VG	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2040202	17971875	XX	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2040202	17971875	XX	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418820	25938565	ADW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418820	25938565	ADW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418820	25938565	ADW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418820	25938565	ADW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418820	25938565	MBU	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418820	25938565	MY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418820	25938565	MY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4418820	25938565	MY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418820	25938565	PCS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418820	25938565	PCS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418820	25938565	PCS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270911	25014534	B.Y.C.	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270911	25014534	Y.-S.K.	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6109037	30143905	All authors	2	have contributed to this research|read and approved the final manuscript	have contributed to this research	-	-	NO
6109037	30143905	All authors	2	have contributed to this research|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5845708	29559990	all authors	2	contributed transversally to the several stages of the work, including its design, data acquisition, analysis and interpretation, critically review of the manuscript, and approval of the submitted version	contributed transversally to the several stages of the work, including its design, data acquisition, analysis and interpretation, critically review of the manuscript, and approval of the submitted version	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Review & Editing	YES
3799575	23982976	AE	2	conceived the experimental strategy and analysed the data|wrote the manuscript	conceived the experimental strategy and analysed the data	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
3799575	23982976	AE	2	conceived the experimental strategy and analysed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3799575	23982976	AK	2	made and analysed hdex experiments	made and analysed hdex experiments	-	-	NO
3799575	23982976	AR	2	purified nbd1	purified nbd1	Performed the experiments	Investigation	YES
3799575	23982976	CN	2	designed the experiments|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
3799575	23982976	CN	2	designed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3799575	23982976	DT	2	performed cell biology experiments	performed cell biology experiments	Performed the experiments	Investigation	YES
3799575	23982976	ES	2	performed mice experiments and presented the data	performed mice experiments and presented the data	Performed the experiments	Investigation	YES
3799575	23982976	FB	2	designed the experiments|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
3799575	23982976	FB	2	designed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3799575	23982976	GF	2	performed spr experiments	performed spr experiments	Performed the experiments	Investigation	YES
3799575	23982976	GL	2	purified nbd1	purified nbd1	Performed the experiments	Investigation	YES
3799575	23982976	GW	2	did molecular dynamics simulations	did molecular dynamics simulations	Performed the experiments	Formal analysis|Investigation	YES
3799575	23982976	HH	2	prepared k8	prepared k8	-	-	NO
3799575	23982976	JC	2	made proximity ligation experiments	made proximity ligation experiments	-	-	NO
3799575	23982976	JF	2	performed patch clamp experiments and the analysis of data|wrote the manuscript	performed patch clamp experiments and the analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3799575	23982976	JF	2	performed patch clamp experiments and the analysis of data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3799575	23982976	KT	2	made and analysed hdex experiments	made and analysed hdex experiments	-	-	NO
3799575	23982976	MD	2	made and analysed hdex experiments	made and analysed hdex experiments	-	-	NO
3799575	23982976	MFC	2	performed mice experiments and presented the data	performed mice experiments and presented the data	Performed the experiments	Investigation	YES
3799575	23982976	MO	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3799575	23982976	NO	2	designed in silico studies|performed in silico studies|wrote the manuscript	designed in silico studies	Conceived and designed the experiments	Formal analysis|Methodology	YES
3799575	23982976	NO	2	designed in silico studies|performed in silico studies|wrote the manuscript	performed in silico studies	Performed the experiments	Formal analysis|Investigation	YES
3799575	23982976	NO	2	designed in silico studies|performed in silico studies|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3799575	23982976	NS	2	performed patch clamp experiments and the analysis of data	performed patch clamp experiments and the analysis of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3799575	23982976	PZ	2	designed in silico studies|wrote the manuscript	designed in silico studies	Conceived and designed the experiments	Formal analysis|Methodology	YES
3799575	23982976	PZ	2	designed in silico studies|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3799575	23982976	SB	2	made proximity ligation experiments	made proximity ligation experiments	-	-	NO
5745857	29299314	RH	2	drafted and approved the final manuscript	drafted and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5790827	29352028	J.G.	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5790827	29352028	Z.A.	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
2040203	17971876	AH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2040203	17971876	AH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2040203	17971876	AH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2040203	17971876	AH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2040203	17971876	DB	PLoS5	Conceived and designed the experiments|Edited the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2040203	17971876	DB	PLoS5	Conceived and designed the experiments|Edited the paper	Edited the paper	Wrote the paper	Writing - Review & Editing	YES
5838960	29510677	AAM	2	developed the website|contributed manuscript sections	developed the website	Contributed reagents/materials/analysis tools	Software	YES
5838960	29510677	AAM	2	developed the website|contributed manuscript sections	contributed manuscript sections	-	-	NO
5838960	29510677	ACG	2	acquired and processed the data	acquired and processed the data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5838960	29510677	ACL	2	acquired and processed the data	acquired and processed the data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5838960	29510677	AS	2	acquired and processed the data	acquired and processed the data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5838960	29510677	All authors	2	participated in the revision process and provided final approval	participated in the revision process and provided final approval	Wrote the paper	Writing - Review & Editing	YES
5838960	29510677	BAR	2	acquired and processed the data	acquired and processed the data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5838960	29510677	CG	2	acquired and processed the data	acquired and processed the data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5838960	29510677	DJC	2	developed the website	developed the website	Contributed reagents/materials/analysis tools	Software	YES
5838960	29510677	DK	2	acquired and processed the data	acquired and processed the data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5838960	29510677	GL	2	acquired and processed the data	acquired and processed the data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5838960	29510677	HIP	2	acquired and processed the data	acquired and processed the data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5838960	29510677	HK	2	developed the website	developed the website	Contributed reagents/materials/analysis tools	Software	YES
5838960	29510677	JRP	2	developed metrics and visualizations|contributed manuscript sections	developed metrics and visualizations	Analyzed the data	Visualization	YES
5838960	29510677	JRP	2	developed metrics and visualizations|contributed manuscript sections	contributed manuscript sections	-	-	NO
5838960	29510677	KK	2	acquired and processed the data	acquired and processed the data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5838960	29510677	KLT	2	acquired and processed the data	acquired and processed the data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5838960	29510677	KVKJ	2	acquired and processed the data	acquired and processed the data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5838960	29510677	LC	2	developed the website|contributed manuscript sections	developed the website	Contributed reagents/materials/analysis tools	Software	YES
5838960	29510677	LC	2	developed the website|contributed manuscript sections	contributed manuscript sections	-	-	NO
5838960	29510677	LKV	2	developed the reference samples|acquired and processed the data	developed the reference samples	-	-	NO
5838960	29510677	LKV	2	developed the reference samples|acquired and processed the data	acquired and processed the data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5838960	29510677	LS	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5838960	29510677	MLS	2	designed the study|developed the reference samples	designed the study	Conceived and designed the experiments	Methodology	YES
5838960	29510677	MLS	2	designed the study|developed the reference samples	developed the reference samples	-	-	NO
5838960	29510677	PSP	2	designed the study|developed the reference samples|developed metrics and visualizations|developed the website|drafted the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5838960	29510677	PSP	2	designed the study|developed the reference samples|developed metrics and visualizations|developed the website|drafted the manuscript	developed the reference samples	-	-	NO
5838960	29510677	PSP	2	designed the study|developed the reference samples|developed metrics and visualizations|developed the website|drafted the manuscript	developed metrics and visualizations	Analyzed the data	Visualization	YES
5838960	29510677	PSP	2	designed the study|developed the reference samples|developed metrics and visualizations|developed the website|drafted the manuscript	developed the website	Contributed reagents/materials/analysis tools	Software	YES
5838960	29510677	PSP	2	designed the study|developed the reference samples|developed metrics and visualizations|developed the website|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5838960	29510677	SAS	2	acquired and processed the data	acquired and processed the data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5838960	29510677	SCK	2	developed the website	developed the website	Contributed reagents/materials/analysis tools	Software	YES
5838960	29510677	SMD	2	acquired and processed the data	acquired and processed the data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
5838960	29510677	SPL	2	developed metrics and visualizations|contributed manuscript sections	developed metrics and visualizations	Analyzed the data	Visualization	YES
5838960	29510677	SPL	2	developed metrics and visualizations|contributed manuscript sections	contributed manuscript sections	-	-	NO
5838960	29510677	SS	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
2040204	17971866	FO	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
2040204	17971866	FO	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2040204	17971866	HK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2040204	17971866	HK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2040204	17971866	HK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2040204	17971866	HK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2040204	17971866	HK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2040204	17971866	TT	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
2040204	17971866	TT	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
2040204	17971866	TT	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418821	25938758	LW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418821	25938758	LW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418821	25938758	LW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418821	25938758	LW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418821	25938758	LW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418821	25938758	TL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4418821	25938758	TL	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
6270912	25170950	All the authors	2	participated in the data interpretation	participated in the data interpretation	Analyzed the data	Formal analysis	YES
6270912	25170950	Angelo Maspero	2	performed the ir spectroscopy measurements	performed the ir spectroscopy measurements	Performed the experiments	Investigation	YES
6270912	25170950	Hanne H. Tonnesen	2	determined the photodegradation half-lives and quantum yields and isolated the photodecomposition products	determined the photodegradation half-lives and quantum yields and isolated the photodecomposition products	Performed the experiments	Investigation	YES
6270912	25170950	ROS	2	generation data	generation data	-	Investigation	YES
3799576	23982961	AJC	2	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
3799576	23982961	AJM	2	analysed the microarray data	analysed the microarray data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3799576	23982961	CAG	2	assisted with in vivo experiments	assisted with in vivo experiments	Performed the experiments	Investigation	YES
3799576	23982961	DEA	2	designed the experiments|provided the dissociated tumour cultures	designed the experiments	Conceived and designed the experiments	Methodology	YES
3799576	23982961	DEA	2	designed the experiments|provided the dissociated tumour cultures	provided the dissociated tumour cultures	Performed the experiments	Investigation	YES
3799576	23982961	DJA	2	designed the experiments|performed most of the experiments, interpreted results and analysed data|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
3799576	23982961	DJA	2	designed the experiments|performed most of the experiments, interpreted results and analysed data|wrote the manuscript	performed most of the experiments, interpreted results and analysed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3799576	23982961	DJA	2	designed the experiments|performed most of the experiments, interpreted results and analysed data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3799576	23982961	DZ	2	generated dt22 expressing luciferase and assisted with in vitro and in vivo experiments|assisted with in vivo experiments|analysed the microarray data	generated dt22 expressing luciferase and assisted with in vitro and in vivo experiments	Performed the experiments	Investigation	YES
3799576	23982961	DZ	2	generated dt22 expressing luciferase and assisted with in vitro and in vivo experiments|assisted with in vivo experiments|analysed the microarray data	assisted with in vivo experiments	Performed the experiments	Investigation	YES
3799576	23982961	DZ	2	generated dt22 expressing luciferase and assisted with in vitro and in vivo experiments|assisted with in vivo experiments|analysed the microarray data	analysed the microarray data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3799576	23982961	JMS	2	designed the experiments|wrote the manuscript|directed this study	designed the experiments	Conceived and designed the experiments	Methodology	YES
3799576	23982961	JMS	2	designed the experiments|wrote the manuscript|directed this study	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3799576	23982961	JMS	2	designed the experiments|wrote the manuscript|directed this study	directed this study	-	Supervision	YES
3799576	23982961	JS	2	conducted experiments including qrt pcr and chip	conducted experiments including qrt pcr and chip	Performed the experiments	Investigation	YES
3799576	23982961	KDE	2	assisted with in vitro experiments	assisted with in vitro experiments	Performed the experiments	Investigation	YES
3799576	23982961	MPR	2	assisted with in vitro experiments	assisted with in vitro experiments	Performed the experiments	Investigation	YES
3799576	23982961	PR	2	designed the experiments|generated mda-mb-231 expressing n1-icd|performed chip experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
3799576	23982961	PR	2	designed the experiments|generated mda-mb-231 expressing n1-icd|performed chip experiments	generated mda-mb-231 expressing n1-icd	Performed the experiments	Investigation	YES
3799576	23982961	PR	2	designed the experiments|generated mda-mb-231 expressing n1-icd|performed chip experiments	performed chip experiments	Performed the experiments	Investigation	YES
3799576	23982961	SAW	2	assisted with in vivo experiments	assisted with in vivo experiments	Performed the experiments	Investigation	YES
3799576	23982961	XH	2	performed chip experiments	performed chip experiments	Performed the experiments	Investigation	YES
5845709	29559983	All authors	2	discussed the results and contributed to the manuscript	discussed the results and contributed to the manuscript	-	-	NO
5753520	29308208	COS	2	contributed to the study design and reviewed the manuscript	contributed to the study design and reviewed the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5753520	29308208	FCL	2	contributed to data analysis and reviewed the manuscript	contributed to data analysis and reviewed the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5753520	29308208	JDJ	2	contributed to the study design, data collection, and data analysis	contributed to the study design, data collection, and data analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Methodology|Resources	YES
5753520	29308208	KA	2	contributed to data collection and reviewed the manuscript	contributed to data collection and reviewed the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5753520	29308208	MPC	2	contributed to the study design, data collection, and data analysis	contributed to the study design, data collection, and data analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Methodology|Resources	YES
5753520	29308208	ND	2	contributed to the study design and data collection and reviewed the manuscript	contributed to the study design and data collection and reviewed the manuscript	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Methodology|Resources|Writing - Review & Editing	YES
4800247	26972711	AGN	2	provided conception and design of research|conceived critical revision of the manuscript	provided conception and design of research	Conceived and designed the experiments	Conceptualization|Methodology	YES
4800247	26972711	AGN	2	provided conception and design of research|conceived critical revision of the manuscript	conceived critical revision of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
4800247	26972711	AR	2	provided conception and design of research|interpreted results of experiments	provided conception and design of research	Conceived and designed the experiments	Conceptualization|Methodology	YES
4800247	26972711	AR	2	provided conception and design of research|interpreted results of experiments	interpreted results of experiments	Analyzed the data	Formal analysis	YES
4800247	26972711	CG	2	performed experiments|interpreted results of experiments	performed experiments	Performed the experiments	Investigation	YES
4800247	26972711	CG	2	performed experiments|interpreted results of experiments	interpreted results of experiments	Analyzed the data	Formal analysis	YES
4800247	26972711	GB	2	provided conception and design of research|conceived critical revision of the manuscript	provided conception and design of research	Conceived and designed the experiments	Conceptualization|Methodology	YES
4800247	26972711	GB	2	provided conception and design of research|conceived critical revision of the manuscript	conceived critical revision of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
4800247	26972711	GF	2	provided conception and design of research|interpreted results of experiments|drafted manuscript|conceived critical revision of the manuscript	provided conception and design of research	Conceived and designed the experiments	Conceptualization|Methodology	YES
4800247	26972711	GF	2	provided conception and design of research|interpreted results of experiments|drafted manuscript|conceived critical revision of the manuscript	interpreted results of experiments	Analyzed the data	Formal analysis	YES
4800247	26972711	GF	2	provided conception and design of research|interpreted results of experiments|drafted manuscript|conceived critical revision of the manuscript	drafted manuscript	Wrote the paper	Writing - Original Draft	YES
4800247	26972711	GF	2	provided conception and design of research|interpreted results of experiments|drafted manuscript|conceived critical revision of the manuscript	conceived critical revision of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
4800247	26972711	GS	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
4800247	26972711	LV	2	provided conception and design of research|performed experiments|interpreted results of experiments|drafted manuscript	provided conception and design of research	Conceived and designed the experiments	Conceptualization|Methodology	YES
4800247	26972711	LV	2	provided conception and design of research|performed experiments|interpreted results of experiments|drafted manuscript	performed experiments	Performed the experiments	Investigation	YES
4800247	26972711	LV	2	provided conception and design of research|performed experiments|interpreted results of experiments|drafted manuscript	interpreted results of experiments	Analyzed the data	Formal analysis	YES
4800247	26972711	LV	2	provided conception and design of research|performed experiments|interpreted results of experiments|drafted manuscript	drafted manuscript	Wrote the paper	Writing - Original Draft	YES
4800247	26972711	RA	2	provided conception and design of research|interpreted results of experiments|drafted manuscript|conceived critical revision of the manuscript	provided conception and design of research	Conceived and designed the experiments	Conceptualization|Methodology	YES
4800247	26972711	RA	2	provided conception and design of research|interpreted results of experiments|drafted manuscript|conceived critical revision of the manuscript	interpreted results of experiments	Analyzed the data	Formal analysis	YES
4800247	26972711	RA	2	provided conception and design of research|interpreted results of experiments|drafted manuscript|conceived critical revision of the manuscript	drafted manuscript	Wrote the paper	Writing - Original Draft	YES
4800247	26972711	RA	2	provided conception and design of research|interpreted results of experiments|drafted manuscript|conceived critical revision of the manuscript	conceived critical revision of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
4800247	26972711	VF	2	provided conception and design of research|conceived critical revision of the manuscript	provided conception and design of research	Conceived and designed the experiments	Conceptualization|Methodology	YES
4800247	26972711	VF	2	provided conception and design of research|conceived critical revision of the manuscript	conceived critical revision of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
4295796	25489978	B.D.W.	2	contributed equally	contributed equally	-	-	NO
4295796	25489978	B.L.	2	contributed equally	contributed equally	-	-	NO
5838962	29510672	EK	2	conceived the study|wrote the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5838962	29510672	EK	2	conceived the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5838962	29510672	JP	2	performed bioinformatic analysis|wrote the manuscript	performed bioinformatic analysis	Performed the experiments	Formal analysis|Investigation	YES
5838962	29510672	JP	2	performed bioinformatic analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5838962	29510672	ML	2	performed bioinformatic analysis|wrote the manuscript	performed bioinformatic analysis	Performed the experiments	Formal analysis|Investigation	YES
5838962	29510672	ML	2	performed bioinformatic analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5838962	29510672	VT	2	performed all experiments|wrote the manuscript	performed all experiments	Performed the experiments	Investigation	YES
5838962	29510672	VT	2	performed all experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6111014	30151682	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6111014	30151682	KEF	2	participated in the study design and coordination and provided critical review of the manuscript	participated in the study design and coordination and provided critical review of the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Review & Editing	YES
6111014	30151682	SO	2	participated in project conception and coordination	participated in project conception and coordination	Conceived and designed the experiments	Conceptualization|Project administration	YES
6111014	30151682	TS	2	participated in project conception and coordination	participated in project conception and coordination	Conceived and designed the experiments	Conceptualization|Project administration	YES
6111014	30151682	The authors	2	declare that they have are no competing interests and certify that there is no conflict of interest with any financial or non-financial organization regarding the contents of the manuscript	declare that they have are no competing interests and certify that there is no conflict of interest with any financial or non-financial organization regarding the contents of the manuscript	-	-	NO
6111014	30151682	YK	2	carried out all the experimental work and participated in the experimental design, as well as coordination and writing of the manuscript|participated in project conception and coordination	carried out all the experimental work and participated in the experimental design, as well as coordination and writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Project administration|Writing - Original Draft	YES
6111014	30151682	YK	2	carried out all the experimental work and participated in the experimental design, as well as coordination and writing of the manuscript|participated in project conception and coordination	participated in project conception and coordination	Conceived and designed the experiments	Conceptualization|Project administration	YES
4418822	25938226	FXZ	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418822	25938226	HG	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418822	25938226	HG	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418822	25938226	HG	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418822	25938226	JZ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418822	25938226	JZ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418822	25938226	JZ	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418822	25938226	LMY	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418822	25938226	LMY	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418822	25938226	LMY	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418822	25938226	QF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418822	25938226	QF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418822	25938226	QF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418822	25938226	QF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418822	25938226	QXC	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418822	25938226	SCY	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
6270913	25379639	Angel R. Hernandez-Martinez	2	had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis	had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis	Analyzed the data	Data curation|Formal analysis	YES
6270913	25379639	Fernando Garcia-Hernandez	2	contributed their ideas for this study and preparation of this manuscript	contributed their ideas for this study and preparation of this manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
6270913	25379639	Manuel Cortez-Valadez	2	realized and interpreted the quantum chemical calculations for betalain molecules	realized and interpreted the quantum chemical calculations for betalain molecules	Analyzed the data	Formal analysis	YES
6270913	25379639	Miriam Estevez	2	contributed their ideas for this study and preparation of this manuscript	contributed their ideas for this study and preparation of this manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
3799577	24092663	AK	2	performed some of the experiments	performed some of the experiments	Performed the experiments	Investigation	YES
3799577	24092663	BDS	2	contributed to the design of some of the experiments and preparation of the manuscript	contributed to the design of some of the experiments and preparation of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
3799577	24092663	CB	2	designed and supervized the study, obtained most of the funding and wrote the manuscript approved by all authors	designed and supervized the study, obtained most of the funding and wrote the manuscript approved by all authors	Conceived and designed the experiments|Wrote the paper	Funding acquisition|Methodology|Supervision|Writing - Original Draft	YES
3799577	24092663	DGE	2	performed the fxs-cancer registry analysis	performed the fxs-cancer registry analysis	Performed the experiments	Investigation	YES
3799577	24092663	ES	2	provided the human samples	provided the human samples	Contributed reagents/materials/analysis tools	Resources	YES
3799577	24092663	FB	2	performed some of the experiments	performed some of the experiments	Performed the experiments	Investigation	YES
3799577	24092663	FDN	2	performed the histopathologycal analysis on human and mouse samples	performed the histopathologycal analysis on human and mouse samples	Performed the experiments	Investigation	YES
3799577	24092663	FZ	2	contributed substantially to the experiments	contributed substantially to the experiments	Performed the experiments	Investigation	YES
3799577	24092663	GLF	2	performed some of the experiments	performed some of the experiments	Performed the experiments	Investigation	YES
3799577	24092663	GN	2	contributed to the design of some of the experiments and preparation of the manuscript	contributed to the design of some of the experiments and preparation of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
3799577	24092663	MA	2	designed, performed the majority of the experiments and helped with the writing of the manuscript	designed, performed the majority of the experiments and helped with the writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
3799577	24092663	MB	2	performed the histopathologycal analysis on human and mouse samples	performed the histopathologycal analysis on human and mouse samples	Performed the experiments	Investigation	YES
3799577	24092663	MGF	2	contributed to the design of some of the experiments and preparation of the manuscript	contributed to the design of some of the experiments and preparation of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
3799577	24092663	MM	2	contributed to the design of some of the experiments and preparation of the manuscript	contributed to the design of some of the experiments and preparation of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
3799577	24092663	MP	2	contributed to the design of some of the experiments and preparation of the manuscript	contributed to the design of some of the experiments and preparation of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
3799577	24092663	MV	2	contributed substantially to the experiments|provided the human samples	contributed substantially to the experiments	Performed the experiments	Investigation	YES
3799577	24092663	MV	2	contributed substantially to the experiments|provided the human samples	provided the human samples	Contributed reagents/materials/analysis tools	Resources	YES
3799577	24092663	PC	2	contributed to the design of some of the experiments and preparation of the manuscript	contributed to the design of some of the experiments and preparation of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
3799577	24092663	PN	2	provided the human samples|performed the histopathologycal analysis on human and mouse samples	provided the human samples	Contributed reagents/materials/analysis tools	Resources	YES
3799577	24092663	PN	2	provided the human samples|performed the histopathologycal analysis on human and mouse samples	performed the histopathologycal analysis on human and mouse samples	Performed the experiments	Investigation	YES
3799577	24092663	PP	2	provided the human samples	provided the human samples	Contributed reagents/materials/analysis tools	Resources	YES
3799577	24092663	RA	2	performed the fxs-cancer registry analysis	performed the fxs-cancer registry analysis	Performed the experiments	Investigation	YES
3799577	24092663	RL	2	designed, performed the majority of the experiments and helped with the writing of the manuscript	designed, performed the majority of the experiments and helped with the writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
3799577	24092663	RM	2	contributes to preliminary experiments not included in this manuscript	contributes to preliminary experiments not included in this manuscript	Performed the experiments	Investigation	YES
3799577	24092663	RN	2	performed some of the experiments	performed some of the experiments	Performed the experiments	Investigation	YES
3799577	24092663	SM	2	helped with the data analysis requiring bright field and confocal microscopy	helped with the data analysis requiring bright field and confocal microscopy	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3799577	24092663	TA	2	contributed to the design of some of the experiments and preparation of the manuscript	contributed to the design of some of the experiments and preparation of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
3799577	24092663	VMF	2	provided the human samples	provided the human samples	Contributed reagents/materials/analysis tools	Resources	YES
2040216	17971867	CH	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
2040216	17971867	CH	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2040216	17971867	JP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2040216	17971867	JP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2040216	17971867	JP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2040216	17971867	JP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2040216	17971867	LW	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2040216	17971867	PD	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2040216	17971867	PD	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2040216	17971867	SP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2040216	17971867	SP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2040216	17971867	SP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2040216	17971867	SP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4800248	26972712	AEA	2	study execution, results analysis, manuscript preparation	study execution, results analysis, manuscript preparation	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4800248	26972712	HA	2	study execution, results analysis, manuscript preparation	study execution, results analysis, manuscript preparation	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4800248	26972712	JH	2	study execution, results analysis, manuscript preparation	study execution, results analysis, manuscript preparation	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4800248	26972712	MEJ	2	study planning, results analysis, manuscript preparation	study planning, results analysis, manuscript preparation	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
6111021	30151668	All	2	data generated or analyzed during this study are included in this manuscripts	data generated or analyzed during this study are included in this manuscripts	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6111021	30151668	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6111021	30151668	DK	2	designed and coordinated the study	designed and coordinated the study	Conceived and designed the experiments	Methodology|Project administration	YES
6111021	30151668	JC	2	performed mushroom spawning, fruiting of mushroom in field scale and preparation of mushroom fruit body extract	performed mushroom spawning, fruiting of mushroom in field scale and preparation of mushroom fruit body extract	Performed the experiments	Investigation	YES
6111021	30151668	JH	2	performed mushroom spawning, fruiting of mushroom in field scale and preparation of mushroom fruit body extract	performed mushroom spawning, fruiting of mushroom in field scale and preparation of mushroom fruit body extract	Performed the experiments	Investigation	YES
6111021	30151668	JK	2	performed buckwheat fermentation, preparation of extracts and component analyses	performed buckwheat fermentation, preparation of extracts and component analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6111021	30151668	KS	2	conducted mushroom component analyses and morphological characterization	conducted mushroom component analyses and morphological characterization	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6111021	30151668	NP	2	participated in antioxidant assay and growth of fungi	participated in antioxidant assay and growth of fungi	Performed the experiments	Investigation	YES
6111021	30151668	SJ	2	conducted mushroom component analyses and morphological characterization	conducted mushroom component analyses and morphological characterization	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6111021	30151668	SK	2	performed buckwheat fermentation, preparation of extracts and component analyses	performed buckwheat fermentation, preparation of extracts and component analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6111021	30151668	TL	2	performed fermentation and drafted manuscript	performed fermentation and drafted manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6111021	30151668	TN	2	carried out cell tests and preparation of revised manuscript	carried out cell tests and preparation of revised manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
6111021	30151668	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5845726	29559991	FH	7	Performed the experiments and wrote the paper|Manuscript revision and approval	Performed the experiments and wrote the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5845726	29559991	FH	7	Performed the experiments and wrote the paper|Manuscript revision and approval	Manuscript revision and approval	Wrote the paper	Writing - Review & Editing	YES
5845726	29559991	TL	7	Manuscript revision and approval	Manuscript revision and approval	Wrote the paper	Writing - Review & Editing	YES
5845726	29559991	XH	7	Manuscript revision and approval|Contributed to the interpretation of the results and coordinated the study	Manuscript revision and approval	Wrote the paper	Writing - Review & Editing	YES
5845726	29559991	XH	7	Manuscript revision and approval|Contributed to the interpretation of the results and coordinated the study	Contributed to the interpretation of the results and coordinated the study	Analyzed the data	Formal analysis|Project administration	YES
5759266	29340154	AS	2	contributed to the study design, data analysis, and manuscript writing	contributed to the study design, data analysis, and manuscript writing	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Original Draft	YES
5759266	29340154	EB	2	performed the data collection and data analyses and was responsible for the manuscript writing	performed the data collection and data analyses and was responsible for the manuscript writing	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5759266	29340154	MB	2	contributed to the statistical analyses and reviewed the manuscript	contributed to the statistical analyses and reviewed the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5759266	29340154	PS	2	contributed to the study design, data analysis, and manuscript writing	contributed to the study design, data analysis, and manuscript writing	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Original Draft	YES
5838963	29506469	AL	2	offered intellectual contributions at various stages of this work and provided critical reviews of the manuscript	offered intellectual contributions at various stages of this work and provided critical reviews of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5838963	29506469	BEE	2	offered intellectual contributions at various stages of this work and provided critical reviews of the manuscript	offered intellectual contributions at various stages of this work and provided critical reviews of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5838963	29506469	CW	2	contributed substantially to the experimental work	contributed substantially to the experimental work	Performed the experiments	Investigation	YES
5838963	29506469	DGPF	2	contributed substantially to the experimental work	contributed substantially to the experimental work	Performed the experiments	Investigation	YES
5838963	29506469	DT	2	offered both intellectual expertise and critical bioinformatics contributions	offered both intellectual expertise and critical bioinformatics contributions	-	Formal analysis	YES
5838963	29506469	MF	2	offered both intellectual expertise and critical bioinformatics contributions	offered both intellectual expertise and critical bioinformatics contributions	-	Formal analysis	YES
5838963	29506469	NAF	2	who also carried out bioinformatics, data analyses and curation, and preparation of the manuscript and figures/tables	who also carried out bioinformatics, data analyses and curation, and preparation of the manuscript and figures/tables	Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Formal analysis|Investigation|Visualization|Writing - Original Draft	YES
5838963	29506469	NC	2	contributed substantially to the experimental work	contributed substantially to the experimental work	Performed the experiments	Investigation	YES
5838963	29506469	RKG	2	carried out bioinformatics and experimental work, data analyses, was involved in writing the manuscript and preparation of figures/tables, and offered intellectual contributions	carried out bioinformatics and experimental work, data analyses, was involved in writing the manuscript and preparation of figures/tables, and offered intellectual contributions	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Visualization|Writing - Original Draft	YES
4418823	25938241	AS	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418823	25938241	AS	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418823	25938241	BTT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418823	25938241	BTT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418823	25938241	BTT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418823	25938241	BTT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418823	25938241	BTT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418823	25938241	DD	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418823	25938241	DD	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418823	25938241	DD	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418823	25938241	GA	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418823	25938241	GA	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418823	25938241	GA	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418823	25938241	KNTM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418823	25938241	KNTM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418823	25938241	KNTM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418823	25938241	OD	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418823	25938241	OD	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418823	25938241	SS	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418823	25938241	SS	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4800249	26972713	all authors	2	had substantial contributions to the acquisition, analysis, or interpretation of data for the work	had substantial contributions to the acquisition, analysis, or interpretation of data for the work	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
3799578	24092664	AM	2	conceived, designed, performed experiments, analysed, interpreted data and made figures|wrote the manuscript	conceived, designed, performed experiments, analysed, interpreted data and made figures	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation|Methodology|Visualization	YES
3799578	24092664	AM	2	conceived, designed, performed experiments, analysed, interpreted data and made figures|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3799578	24092664	CM	2	performed in situ hybridization and immunohistochemistry analyses and interpreted data	performed in situ hybridization and immunohistochemistry analyses and interpreted data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3799578	24092664	GH	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
3799578	24092664	JL	2	conceived, designed, performed experiments, analysed, interpreted data and made figures	conceived, designed, performed experiments, analysed, interpreted data and made figures	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation|Methodology|Visualization	YES
3799578	24092664	JR	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3799578	24092664	MA	2	carried out experiments with xenotransplantation of patient material and interpreted data	carried out experiments with xenotransplantation of patient material and interpreted data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3799578	24092664	MS	2	carried out mass spectrometry	carried out mass spectrometry	Performed the experiments	Investigation	YES
3799578	24092664	SB	2	conceived, designed, performed experiments, analysed, interpreted data and made figures	conceived, designed, performed experiments, analysed, interpreted data and made figures	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation|Methodology|Visualization	YES
3799578	24092664	SPG	2	carried out experiments with xenotransplantation of patient material and interpreted data	carried out experiments with xenotransplantation of patient material and interpreted data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3799578	24092664	SS	2	performed statistical analysis	performed statistical analysis	Analyzed the data	Formal analysis	YES
3799578	24092664	SVD	2	performed in situ hybridization and immunohistochemistry analyses and interpreted data	performed in situ hybridization and immunohistochemistry analyses and interpreted data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3799578	24092664	TM	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
3799578	24092664	ZR	2	carried out experiments with xenotransplantation of patient material and interpreted data	carried out experiments with xenotransplantation of patient material and interpreted data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5845730	29559987	BK	PLoS52	designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
5845730	29559987	LL	PLoS52	designed the research|analyzed the data|wrote the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
5845730	29559987	LL	PLoS52	designed the research|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5845730	29559987	LL	PLoS52	designed the research|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5845730	29559987	YJ	PLoS52	designed the research|performed the experiments|analyzed the data	designed the research	Conceived and designed the experiments	Methodology	YES
5845730	29559987	YJ	PLoS52	designed the research|performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5845730	29559987	YJ	PLoS52	designed the research|performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5845730	29559987	YS	PLoS52	designed the research|performed the experiments|analyzed the data	designed the research	Conceived and designed the experiments	Methodology	YES
5845730	29559987	YS	PLoS52	designed the research|performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5845730	29559987	YS	PLoS52	designed the research|performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
6113197	30155810	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6113197	30155810	BXW	PLoS52	defined, discussed and were key in the approval of the research design|wrote the article	defined, discussed and were key in the approval of the research design	Conceived and designed the experiments	-	YES
6113197	30155810	BXW	PLoS52	defined, discussed and were key in the approval of the research design|wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
6113197	30155810	CJZ	PLoS52	defined, discussed and were key in the approval of the research design|wrote the article	defined, discussed and were key in the approval of the research design	Conceived and designed the experiments	-	YES
6113197	30155810	CJZ	PLoS52	defined, discussed and were key in the approval of the research design|wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
6113197	30155810	FLM	PLoS52	defined, discussed and were key in the approval of the research design|analyzed the data|wrote the article	defined, discussed and were key in the approval of the research design	Conceived and designed the experiments	-	YES
6113197	30155810	FLM	PLoS52	defined, discussed and were key in the approval of the research design|analyzed the data|wrote the article	analyzed the data	Analyzed the data	Formal analysis	YES
6113197	30155810	FLM	PLoS52	defined, discussed and were key in the approval of the research design|analyzed the data|wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
6113197	30155810	HGD	PLoS52	defined, discussed and were key in the approval of the research design	defined, discussed and were key in the approval of the research design	Conceived and designed the experiments	-	YES
6113197	30155810	Jacob Ojobi Omedi	PLoS52	for his valuable time to edit this article	for his valuable time to edit this article	Wrote the paper	Writing - Review & Editing	YES
6113197	30155810	KB	PLoS52	defined, discussed and were key in the approval of the research design|performed the research|analyzed the data|wrote the article	defined, discussed and were key in the approval of the research design	Conceived and designed the experiments	-	YES
6113197	30155810	KB	PLoS52	defined, discussed and were key in the approval of the research design|performed the research|analyzed the data|wrote the article	performed the research	Performed the experiments	Investigation	YES
6113197	30155810	KB	PLoS52	defined, discussed and were key in the approval of the research design|performed the research|analyzed the data|wrote the article	analyzed the data	Analyzed the data	Formal analysis	YES
6113197	30155810	KB	PLoS52	defined, discussed and were key in the approval of the research design|performed the research|analyzed the data|wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
6113197	30155810	MSL	PLoS52	defined, discussed and were key in the approval of the research design|wrote the article	defined, discussed and were key in the approval of the research design	Conceived and designed the experiments	-	YES
6113197	30155810	MSL	PLoS52	defined, discussed and were key in the approval of the research design|wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
6113197	30155810	SC	PLoS52	defined, discussed and were key in the approval of the research design|analyzed the data	defined, discussed and were key in the approval of the research design	Conceived and designed the experiments	-	YES
6113197	30155810	SC	PLoS52	defined, discussed and were key in the approval of the research design|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
6113197	30155810	SLL	PLoS52	defined, discussed and were key in the approval of the research design|performed the research	defined, discussed and were key in the approval of the research design	Conceived and designed the experiments	-	YES
6113197	30155810	SLL	PLoS52	defined, discussed and were key in the approval of the research design|performed the research	performed the research	Performed the experiments	Investigation	YES
6113197	30155810	The authors	PLoS52	declare that that no competing interests exist	declare that that no competing interests exist	-	-	NO
6113197	30155810	XP	PLoS52	defined, discussed and were key in the approval of the research design|wrote the article	defined, discussed and were key in the approval of the research design	Conceived and designed the experiments	-	YES
6113197	30155810	XP	PLoS52	defined, discussed and were key in the approval of the research design|wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
6113197	30155810	ZC	PLoS52	defined, discussed and were key in the approval of the research design|analyzed the data	defined, discussed and were key in the approval of the research design	Conceived and designed the experiments	-	YES
6113197	30155810	ZC	PLoS52	defined, discussed and were key in the approval of the research design|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
6113197	30155810	ZY	PLoS52	defined, discussed and were key in the approval of the research design|analyzed the data	defined, discussed and were key in the approval of the research design	Conceived and designed the experiments	-	YES
6113197	30155810	ZY	PLoS52	defined, discussed and were key in the approval of the research design|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
6270914	24968330	X.G.S.	PLoS52	designed and performed the experiments	designed and performed the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6270914	24968330	X.M.Y.	PLoS52	performed the experiment	performed the experiment	Performed the experiments	Investigation	YES
6270914	24968330	Y.X.K.	PLoS52	designed and performed the experiments|wrote the paper	designed and performed the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6270914	24968330	Y.X.K.	PLoS52	designed and performed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270914	24968330	Z.X.X.	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
6270914	24968330	Z.Y.L.	PLoS52	performed the experiment	performed the experiment	Performed the experiments	Investigation	YES
5775536	29387419	KMH	2	contributed to the design of the study, data collection, analysis, and drafting of the manuscript	contributed to the design of the study, data collection, analysis, and drafting of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft	YES
5775536	29387419	YH	2	contributed to the design of the study, interpretation of the data, and drafting the manuscript	contributed to the design of the study, interpretation of the data, and drafting the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Original Draft	YES
2040217	17971857	BS	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2040217	17971857	BS	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2040217	17971857	DH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
2040217	17971857	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2040217	17971857	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2040217	17971857	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2040217	17971857	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2040217	17971857	JL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2040217	17971857	KJ	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2040217	17971857	KJ	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2040217	17971857	LM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
2040217	17971857	OB	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2040217	17971857	PK	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2040217	17971857	PK	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418824	25938568	ACM	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418824	25938568	DR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418824	25938568	DR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418824	25938568	DR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418824	25938568	DR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418824	25938568	DR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418824	25938568	EBH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418824	25938568	GL	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418824	25938568	HM	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418824	25938568	JAF	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418824	25938568	JAF	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5838969	29510662	All	2	authors contributed to review and revision of the manuscript	authors contributed to review and revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5838969	29510662	BDH	2	conceived and designed study to analyze effect of alternate input on high-density microarrays|coordinated the study|contributed to interpretation of data during regular project meetings|authors contributed to review and revision of the manuscript	conceived and designed study to analyze effect of alternate input on high-density microarrays	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation|Methodology	YES
5838969	29510662	BDH	2	conceived and designed study to analyze effect of alternate input on high-density microarrays|coordinated the study|contributed to interpretation of data during regular project meetings|authors contributed to review and revision of the manuscript	coordinated the study	-	Project administration	YES
5838969	29510662	BDH	2	conceived and designed study to analyze effect of alternate input on high-density microarrays|coordinated the study|contributed to interpretation of data during regular project meetings|authors contributed to review and revision of the manuscript	contributed to interpretation of data during regular project meetings	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5838969	29510662	BDH	2	conceived and designed study to analyze effect of alternate input on high-density microarrays|coordinated the study|contributed to interpretation of data during regular project meetings|authors contributed to review and revision of the manuscript	authors contributed to review and revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5838969	29510662	CLD	2	conceived and designed study to analyze effect of alternate input on high-density microarrays|coordinated the study|performed data analysis|contributed to interpretation of data during regular project meetings	conceived and designed study to analyze effect of alternate input on high-density microarrays	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation|Methodology	YES
5838969	29510662	CLD	2	conceived and designed study to analyze effect of alternate input on high-density microarrays|coordinated the study|performed data analysis|contributed to interpretation of data during regular project meetings	coordinated the study	-	Project administration	YES
5838969	29510662	CLD	2	conceived and designed study to analyze effect of alternate input on high-density microarrays|coordinated the study|performed data analysis|contributed to interpretation of data during regular project meetings	performed data analysis	Analyzed the data	Formal analysis	YES
5838969	29510662	CLD	2	conceived and designed study to analyze effect of alternate input on high-density microarrays|coordinated the study|performed data analysis|contributed to interpretation of data during regular project meetings	contributed to interpretation of data during regular project meetings	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5838969	29510662	EK	2	performed data analysis	performed data analysis	Analyzed the data	Formal analysis	YES
5838969	29510662	GAR	2	contributed sample collections and validated associated data	contributed sample collections and validated associated data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources|Validation	YES
5838969	29510662	GTA	2	contributed sample collections and validated associated data	contributed sample collections and validated associated data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources|Validation	YES
5838969	29510662	JNS	2	performed data analysis	performed data analysis	Analyzed the data	Formal analysis	YES
5838969	29510662	KSL	2	performed the microarray assays generating raw data	performed the microarray assays generating raw data	Performed the experiments	Investigation	YES
5838969	29510662	KT	2	performed the microarray assays generating raw data	performed the microarray assays generating raw data	Performed the experiments	Investigation	YES
5838969	29510662	LLR	2	contributed sample collections and validated associated data	contributed sample collections and validated associated data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources|Validation	YES
5838969	29510662	LMM	2	conceived and designed study to analyze effect of alternate input on high-density microarrays|coordinated the study|contributed sample collections and validated associated data|contributed to interpretation of data during regular project meetings|authors contributed to review and revision of the manuscript	conceived and designed study to analyze effect of alternate input on high-density microarrays	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation|Methodology	YES
5838969	29510662	LMM	2	conceived and designed study to analyze effect of alternate input on high-density microarrays|coordinated the study|contributed sample collections and validated associated data|contributed to interpretation of data during regular project meetings|authors contributed to review and revision of the manuscript	coordinated the study	-	Project administration	YES
5838969	29510662	LMM	2	conceived and designed study to analyze effect of alternate input on high-density microarrays|coordinated the study|contributed sample collections and validated associated data|contributed to interpretation of data during regular project meetings|authors contributed to review and revision of the manuscript	contributed sample collections and validated associated data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources|Validation	YES
5838969	29510662	LMM	2	conceived and designed study to analyze effect of alternate input on high-density microarrays|coordinated the study|contributed sample collections and validated associated data|contributed to interpretation of data during regular project meetings|authors contributed to review and revision of the manuscript	contributed to interpretation of data during regular project meetings	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5838969	29510662	LMM	2	conceived and designed study to analyze effect of alternate input on high-density microarrays|coordinated the study|contributed sample collections and validated associated data|contributed to interpretation of data during regular project meetings|authors contributed to review and revision of the manuscript	authors contributed to review and revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5838969	29510662	MAT	2	contributed to interpretation of data during regular project meetings|authors contributed to review and revision of the manuscript	contributed to interpretation of data during regular project meetings	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5838969	29510662	MAT	2	contributed to interpretation of data during regular project meetings|authors contributed to review and revision of the manuscript	authors contributed to review and revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5838969	29510662	MY	2	conceived and designed study to analyze effect of alternate input on high-density microarrays|contributed to interpretation of data during regular project meetings|authors contributed to review and revision of the manuscript	conceived and designed study to analyze effect of alternate input on high-density microarrays	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceptualization|Formal analysis|Investigation|Methodology	YES
5838969	29510662	MY	2	conceived and designed study to analyze effect of alternate input on high-density microarrays|contributed to interpretation of data during regular project meetings|authors contributed to review and revision of the manuscript	contributed to interpretation of data during regular project meetings	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5838969	29510662	MY	2	conceived and designed study to analyze effect of alternate input on high-density microarrays|contributed to interpretation of data during regular project meetings|authors contributed to review and revision of the manuscript	authors contributed to review and revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5838969	29510662	SB	2	contributed sample collections and validated associated data	contributed sample collections and validated associated data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources|Validation	YES
5838969	29510662	SC	2	performed the microarray assays generating raw data	performed the microarray assays generating raw data	Performed the experiments	Investigation	YES
5838969	29510662	SJC	2	contributed to interpretation of data during regular project meetings|authors contributed to review and revision of the manuscript	contributed to interpretation of data during regular project meetings	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5838969	29510662	SJC	2	contributed to interpretation of data during regular project meetings|authors contributed to review and revision of the manuscript	authors contributed to review and revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5838969	29510662	SL	2	performed data analysis	performed data analysis	Analyzed the data	Formal analysis	YES
5838969	29510662	SMD	2	contributed sample collections and validated associated data	contributed sample collections and validated associated data	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources|Validation	YES
5838969	29510662	WZ	2	performed data analysis	performed data analysis	Analyzed the data	Formal analysis	YES
5845732	29559984	AK	2	helped in the experiments dealing with wheat transformation	helped in the experiments dealing with wheat transformation	Performed the experiments	Investigation	YES
5845732	29559984	AP	2	conceived the idea and designed the experiments|wrote the article	conceived the idea and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5845732	29559984	AP	2	conceived the idea and designed the experiments|wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
5845732	29559984	GK	2	performed the experiments related to transporters	performed the experiments related to transporters	Performed the experiments	Investigation	YES
5845732	29559984	KB	2	helped in the experiments dealing with wheat transformation|wrote the article	helped in the experiments dealing with wheat transformation	Performed the experiments	Investigation	YES
5845732	29559984	KB	2	helped in the experiments dealing with wheat transformation|wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
5845732	29559984	SA	2	performed most of the experiment|wrote the article	performed most of the experiment	Performed the experiments	Investigation	YES
5845732	29559984	SA	2	performed most of the experiment|wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
5845732	29559984	ST	2	helped in the experiments dealing with wheat transformation|wrote the article	helped in the experiments dealing with wheat transformation	Performed the experiments	Investigation	YES
5845732	29559984	ST	2	helped in the experiments dealing with wheat transformation|wrote the article	wrote the article	Wrote the paper	Writing - Original Draft	YES
5845732	29559984	VS	2	performed the experiments related to transporters	performed the experiments related to transporters	Performed the experiments	Investigation	YES
6119174	30171356	All authors	2	read and approved the manuscript	read and approved the manuscript	-	-	NO
6119174	30171356	DZ	2	worked primarily on experimental studies and data acquisition	worked primarily on experimental studies and data acquisition	Performed the experiments	Investigation	YES
6119174	30171356	GZ	2	reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
6119174	30171356	JH	2	contributed to experimental design, data analysis/interpretation, manuscript preparation, and manuscript editing	contributed to experimental design, data analysis/interpretation, manuscript preparation, and manuscript editing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Methodology|Resources|Writing - Original Draft|Writing - Review & Editing	YES
6119174	30171356	New Century Excellent	2	in minnan normal university	in minnan normal university	-	-	NO
6119174	30171356	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
6119174	30171356	YO	2	conducted literature research, experimental studies, data acquisition, and statistical analysis	conducted literature research, experimental studies, data acquisition, and statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6119174	30171356	YP	2	conceived and designed the study, and was the guarantor of integrity for the entire project	conceived and designed the study, and was the guarantor of integrity for the entire project	Conceived and designed the experiments	Conceptualization|Methodology	YES
3799579	23996934	BD	2	designed experiments, supervised all experiments, analysed data, wrote manuscript	designed experiments, supervised all experiments, analysed data, wrote manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Supervision|Writing - Original Draft	YES
3799579	23996934	BJA	2	analysed data	analysed data	Analyzed the data	Formal analysis	YES
3799579	23996934	DDO	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
3799579	23996934	DFS	2	supplied research material	supplied research material	Contributed reagents/materials/analysis tools	Resources	YES
3799579	23996934	DO	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
3799579	23996934	HB-H	2	supplied research material	supplied research material	Contributed reagents/materials/analysis tools	Resources	YES
3799579	23996934	OH-S	2	designed experiments, performed experiments, analysed data and wrote manuscript	designed experiments, performed experiments, analysed data and wrote manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
3799579	23996934	PH	2	analysed data and wrote manuscript	analysed data and wrote manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3799579	23996934	RG	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
3799579	23996934	RSG	2	analysed data	analysed data	Analyzed the data	Formal analysis	YES
3799579	23996934	SM	2	designed experiments, performed experiments and analysed data	designed experiments, performed experiments and analysed data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
3799579	23996934	SP-C	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
3799579	23996934	TN	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
3799579	23996934	YG	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
3799579	23996934	YL	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
3799579	23996934	ZV	2	supplied research material	supplied research material	Contributed reagents/materials/analysis tools	Resources	YES
4800250	26972714	AO	2	participation in study and cases selection	participation in study and cases selection	-	-	NO
4800250	26972714	AP	2	study conception and design, manuscript drafting	study conception and design, manuscript drafting	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
4800250	26972714	All authors	2	were involved in writing the paper and approved the submitted and published versions	were involved in writing the paper and approved the submitted and published versions	Wrote the paper	Writing - Original Draft	YES
4800250	26972714	EB	2	study conception and design, manuscript drafting	study conception and design, manuscript drafting	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
4800250	26972714	FM	2	participation in study and cases selection	participation in study and cases selection	-	-	NO
4800250	26972714	LA	2	case selection and morphological classification	case selection and morphological classification	Performed the experiments	Investigation	YES
4800250	26972714	LTM	2	participation in study and cases selection	participation in study and cases selection	-	-	NO
4800250	26972714	MS	2	study conception and design, manuscript drafting	study conception and design, manuscript drafting	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
6270916	24995921	BEWL	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
6270916	24995921	LSS	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
6270916	24995921	MMC	PLoS52	designed research|performed research and analyzed the data|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
6270916	24995921	MMC	PLoS52	designed research|performed research and analyzed the data|wrote the paper	performed research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270916	24995921	MMC	PLoS52	designed research|performed research and analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270916	24995921	RAM	PLoS52	designed research|analyzed the data|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
6270916	24995921	RAM	PLoS52	designed research|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
6270916	24995921	RAM	PLoS52	designed research|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
2040218	17971870	FJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2040218	17971870	FJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2040218	17971870	FJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2040218	17971870	GG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
2040218	17971870	MR	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
2040218	17971870	YH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2040218	17971870	YH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2040218	17971870	YH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2040218	17971870	YH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5781271	29403646	All authors	2	participated in coding the validation and analysis|participated in revising the draft	participated in coding the validation and analysis	Performed the experiments	Validation	YES
5781271	29403646	All authors	2	participated in coding the validation and analysis|participated in revising the draft	participated in revising the draft	Wrote the paper	Writing - Original Draft	YES
5781271	29403646	BHC	2	conceived and designed the original study	conceived and designed the original study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5781271	29403646	EK	2	completed the interviews|completed the coding	completed the interviews	Performed the experiments	Investigation	YES
5781271	29403646	EK	2	completed the interviews|completed the coding	completed the coding	-	-	NO
5781271	29403646	FL	2	conceived and designed the original study|completed the coding|drafted the manuscript	conceived and designed the original study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5781271	29403646	FL	2	conceived and designed the original study|completed the coding|drafted the manuscript	completed the coding	-	-	NO
5781271	29403646	FL	2	conceived and designed the original study|completed the coding|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5781271	29403646	JJF	2	conceived and designed the original study	conceived and designed the original study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5781271	29403646	SLG	2	conceived and designed the original study|completed the coding|drafted the manuscript	conceived and designed the original study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5781271	29403646	SLG	2	conceived and designed the original study|completed the coding|drafted the manuscript	completed the coding	-	-	NO
5781271	29403646	SLG	2	conceived and designed the original study|completed the coding|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
4672115	26688810	The authors	2	contributed equally to this work	contributed equally to this work	-	-	NO
4800251	26972715	AI	2	supervision and discussion of the study	supervision and discussion of the study	-	Supervision	YES
4800251	26972715	KO	2	supervision and discussion of the study	supervision and discussion of the study	-	Supervision	YES
4800251	26972715	TK	2	experiments performing, manuscript drafting	experiments performing, manuscript drafting	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4800251	26972715	TN	2	supervision and discussion of the study	supervision and discussion of the study	-	Supervision	YES
4418825	25938776	MKB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418825	25938776	MKB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418825	25938776	MKB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418825	25938776	MKB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418825	25938776	PV	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418825	25938776	SAN	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418825	25938776	SB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4418825	25938776	SB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4418825	25938776	SB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418825	25938776	SBB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418825	25938776	SL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5790835	29352036	All authors	2	contributed actively to the writing of this paper and have approved the final version of the manuscript	contributed actively to the writing of this paper and have approved the final version of the manuscript	Wrote the paper	Writing - Original Draft	YES
5845851	29563918	ACUF	PLoS52	designed the research|performed the research|analyzed the data|wrote the paper	designed the research	Conceived and designed the experiments	Methodology	YES
5845851	29563918	ACUF	PLoS52	designed the research|performed the research|analyzed the data|wrote the paper	performed the research	Performed the experiments	Investigation	YES
5845851	29563918	ACUF	PLoS52	designed the research|performed the research|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5845851	29563918	ACUF	PLoS52	designed the research|performed the research|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5845851	29563918	AH	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5845851	29563918	AL	PLoS52	performed the research	performed the research	Performed the experiments	Investigation	YES
5845851	29563918	DM	PLoS52	performed the research	performed the research	Performed the experiments	Investigation	YES
5845851	29563918	FO	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5845851	29563918	GK	PLoS52	designed the research|performed the research|analyzed the data|wrote the paper	designed the research	Conceived and designed the experiments	Methodology	YES
5845851	29563918	GK	PLoS52	designed the research|performed the research|analyzed the data|wrote the paper	performed the research	Performed the experiments	Investigation	YES
5845851	29563918	GK	PLoS52	designed the research|performed the research|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5845851	29563918	GK	PLoS52	designed the research|performed the research|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5845851	29563918	JG	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5845851	29563918	MKP	PLoS52	designed the research|performed the research|analyzed the data|wrote the paper	designed the research	Conceived and designed the experiments	Methodology	YES
5845851	29563918	MKP	PLoS52	designed the research|performed the research|analyzed the data|wrote the paper	performed the research	Performed the experiments	Investigation	YES
5845851	29563918	MKP	PLoS52	designed the research|performed the research|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5845851	29563918	MKP	PLoS52	designed the research|performed the research|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5845851	29563918	MRZ	PLoS52	designed the research|analyzed the data|wrote the paper	designed the research	Conceived and designed the experiments	Methodology	YES
5845851	29563918	MRZ	PLoS52	designed the research|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5845851	29563918	MRZ	PLoS52	designed the research|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5845851	29563918	NT	PLoS52	performed the research	performed the research	Performed the experiments	Investigation	YES
5845851	29563918	RO	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5845851	29563918	TW	PLoS52	designed the research|performed the research|analyzed the data|wrote the paper	designed the research	Conceived and designed the experiments	Methodology	YES
5845851	29563918	TW	PLoS52	designed the research|performed the research|analyzed the data|wrote the paper	performed the research	Performed the experiments	Investigation	YES
5845851	29563918	TW	PLoS52	designed the research|performed the research|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5845851	29563918	TW	PLoS52	designed the research|performed the research|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270917	24402200	Congyan Liu	2	helped write the paper	helped write the paper	Wrote the paper	Writing - Original Draft	YES
6270917	24402200	Ding Qu	2	helped write the paper	helped write the paper	Wrote the paper	Writing - Original Draft	YES
6270917	24402200	Jing Zhou	2	helped write the paper	helped write the paper	Wrote the paper	Writing - Original Draft	YES
6270917	24402200	Xia Gao	2	helped write the paper	helped write the paper	Wrote the paper	Writing - Original Draft	YES
6270917	24402200	Yan Chen	2	designed experiments, performed the research	designed experiments, performed the research	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6270917	24402200	Ying Wang	2	performed research, wrote the paper	performed research, wrote the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6123327	30182189	ABP	PLoS52	conceived and designed the experiments|did the experiments|analyzed the data and wrote this manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6123327	30182189	ABP	PLoS52	conceived and designed the experiments|did the experiments|analyzed the data and wrote this manuscript	did the experiments	Performed the experiments	Investigation	YES
6123327	30182189	ABP	PLoS52	conceived and designed the experiments|did the experiments|analyzed the data and wrote this manuscript	analyzed the data and wrote this manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6123327	30182189	AJK	PLoS52	did the experiments|analyzed the data and wrote this manuscript	did the experiments	Performed the experiments	Investigation	YES
6123327	30182189	AJK	PLoS52	did the experiments|analyzed the data and wrote this manuscript	analyzed the data and wrote this manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6123327	30182189	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6123327	30182189	HK	PLoS52	conceived and designed the experiments|analyzed the data and wrote this manuscript	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6123327	30182189	HK	PLoS52	conceived and designed the experiments|analyzed the data and wrote this manuscript	analyzed the data and wrote this manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6123327	30182189	RGCB	PLoS52	for providing the infrastructure facilities	for providing the infrastructure facilities	-	-	NO
6123327	30182189	The authors	PLoS52	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5784703	29416868	AV	2	were involved in the study design, statistical methodology, interpretation of results, and writing of the manuscript	were involved in the study design, statistical methodology, interpretation of results, and writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5784703	29416868	EB	2	contributed to data collection	contributed to data collection	Performed the experiments	Investigation	YES
5784703	29416868	KJ	2	contributed to data collection	contributed to data collection	Performed the experiments	Investigation	YES
5784703	29416868	KP	2	contributed to data collection|were involved in the study design, statistical methodology, interpretation of results, and writing of the manuscript	contributed to data collection	Performed the experiments	Investigation	YES
5784703	29416868	KP	2	contributed to data collection|were involved in the study design, statistical methodology, interpretation of results, and writing of the manuscript	were involved in the study design, statistical methodology, interpretation of results, and writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5784703	29416868	NW	2	were involved in the study design, statistical methodology, interpretation of results, and writing of the manuscript	were involved in the study design, statistical methodology, interpretation of results, and writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5784703	29416868	VM	2	contributed to data collection	contributed to data collection	Performed the experiments	Investigation	YES
5784703	29416868	VZ	2	contributed to data collection|were involved in the study design, statistical methodology, interpretation of results, and writing of the manuscript	contributed to data collection	Performed the experiments	Investigation	YES
5784703	29416868	VZ	2	contributed to data collection|were involved in the study design, statistical methodology, interpretation of results, and writing of the manuscript	were involved in the study design, statistical methodology, interpretation of results, and writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3913510	24526920	Haishan Deng	2	contributed equally to this work	contributed equally to this work	-	-	NO
3913510	24526920	Shaofei Xie	2	contributed equally to this work	contributed equally to this work	-	-	NO
3799580	24014378	AP	2	performed blinded , in vivo experiments in the neonate trial	performed blinded , in vivo experiments in the neonate trial	Performed the experiments	Investigation	YES
3799580	24014378	AS	2	performed blinded , in vivo experiments in the neonate trial	performed blinded , in vivo experiments in the neonate trial	Performed the experiments	Investigation	YES
3799580	24014378	BCD	2	performed dissection and immunology experiments and is actively participating in preclinical development	performed dissection and immunology experiments and is actively participating in preclinical development	Performed the experiments	Investigation	YES
3799580	24014378	BKM	2	performed blinded , in vivo experiments in the neonate trial	performed blinded , in vivo experiments in the neonate trial	Performed the experiments	Investigation	YES
3799580	24014378	CA	2	designed and provided x-ray imaging, services, instruction and data processing for x-ray experiments	designed and provided x-ray imaging, services, instruction and data processing for x-ray experiments	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Methodology|Resources|Supervision|Visualization	YES
3799580	24014378	CNMC	2	provided the core equipment/services, provided funding, and participated in experimental design and analysis	provided the core equipment/services, provided funding, and participated in experimental design and analysis	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Funding acquisition|Investigation|Methodology|Resources	YES
3799580	24014378	CRH	2	designed, performed, and managed in vitro experiments and the in vivo pre-symptomatic trial, analysed data from both trials and wrote the paper	designed, performed, and managed in vitro experiments and the in vivo pre-symptomatic trial, analysed data from both trials and wrote the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Formal analysis|Investigation|Methodology|Project administration|Writing - Original Draft	YES
3799580	24014378	EKMR	2	helped to identify vbp15, is actively involved in preclinical development, contributed to data analysis/interpretation, provided mentorship and participated in trial and experimental design	helped to identify vbp15, is actively involved in preclinical development, contributed to data analysis/interpretation, provided mentorship and participated in trial and experimental design	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology|Supervision	YES
3799580	24014378	EMC	2	are responsible for identifying and developing the vbp compounds towards clinical development	are responsible for identifying and developing the vbp compounds towards clinical development	Performed the experiments	Investigation	YES
3799580	24014378	EPH	2	provided mentorship, funding, input into experimental design, and helped to write the paper	provided mentorship, funding, input into experimental design, and helped to write the paper	Conceived and designed the experiments|Wrote the paper	Funding acquisition|Methodology|Supervision|Writing - Original Draft	YES
3799580	24014378	HGD	2	performed statistical analyses for the two in vivo trials	performed statistical analyses for the two in vivo trials	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3799580	24014378	JHVM	2	performed specialized in vivo muscle physiology experiments	performed specialized in vivo muscle physiology experiments	Performed the experiments	Investigation	YES
3799580	24014378	JMM	2	are responsible for identifying and developing the vbp compounds towards clinical development	are responsible for identifying and developing the vbp compounds towards clinical development	Performed the experiments	Investigation	YES
3799580	24014378	JQ	2	performed blinded histopathology experiments	performed blinded histopathology experiments	Performed the experiments	Investigation	YES
3799580	24014378	KN	2	contributed greatly to experimental designs, provided mentorship, funding, data analysis/interpretation, facilitated the in vivo preclinical trials, and helped to write the paper	contributed greatly to experimental designs, provided mentorship, funding, data analysis/interpretation, facilitated the in vivo preclinical trials, and helped to write the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Funding acquisition|Investigation|Methodology|Resources|Supervision|Writing - Original Draft	YES
3799580	24014378	KT	2	performed blinded histopathology experiments	performed blinded histopathology experiments	Performed the experiments	Investigation	YES
3799580	24014378	LS	2	performed initial in vitro injury experiments, provided training, and helped to interpret data	performed initial in vitro injury experiments, provided training, and helped to interpret data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
3799580	24014378	MC	2	contributed to histology experiment design and provided automated imaging, blinding and randomization	contributed to histology experiment design and provided automated imaging, blinding and randomization	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Investigation|Methodology|Visualization	YES
3799580	24014378	OCR	2	designed and provided x-ray imaging, services, instruction and data processing for x-ray experiments	designed and provided x-ray imaging, services, instruction and data processing for x-ray experiments	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Data curation|Methodology|Resources|Supervision|Visualization	YES
3799580	24014378	QY	2	performed several specialized mouse imaging experiments	performed several specialized mouse imaging experiments	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
3799580	24014378	SD	2	designed and performed in vivo adult preclinical trial experiments	designed and performed in vivo adult preclinical trial experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3799580	24014378	SJ	2	designed and performed in vivo adult preclinical trial experiments	designed and performed in vivo adult preclinical trial experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3799580	24014378	TH	2	contributed to the design and interpretation of experiments, and helped to perform in vivo experiments	contributed to the design and interpretation of experiments, and helped to perform in vivo experiments	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
3799580	24014378	VBP	2	compound development	compound development	Performed the experiments	Investigation	YES
5812972	29440525	A.R.	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5812972	29440525	C.M.	2	conceived and designed the study|drafted the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5812972	29440525	C.M.	2	conceived and designed the study|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5812972	29440525	M.C.T.	2	conceived and designed the study|performed analysis|drafted the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5812972	29440525	M.C.T.	2	conceived and designed the study|performed analysis|drafted the manuscript	performed analysis	Performed the experiments	Investigation	YES
5812972	29440525	M.C.T.	2	conceived and designed the study|performed analysis|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5812972	29440525	S.M.	2	conceived and designed the study|collected data|drafted the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5812972	29440525	S.M.	2	conceived and designed the study|collected data|drafted the manuscript	collected data	Performed the experiments	Investigation	YES
5812972	29440525	S.M.	2	conceived and designed the study|collected data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5839033	29506476	BVB	2	collected samples, provided advice on snail culturing and revised the manuscript	collected samples, provided advice on snail culturing and revised the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5839033	29506476	HH	2	collected samples, provided advice on snail culturing and revised the manuscript	collected samples, provided advice on snail culturing and revised the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5839033	29506476	HM	2	coordinated the experiments and revised the manuscript	coordinated the experiments and revised the manuscript	Wrote the paper	Project administration|Writing - Review & Editing	YES
5839033	29506476	JCHI	2	performed the experiments, data analyses and drafted the manuscript	performed the experiments, data analyses and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5839033	29506476	JS	2	coordinated the experiments and revised the manuscript	coordinated the experiments and revised the manuscript	Wrote the paper	Project administration|Writing - Review & Editing	YES
5839033	29506476	JWQ	2	designed and oversaw the study, and revised the manuscript	designed and oversaw the study, and revised the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Review & Editing	YES
5839033	29506476	MG	2	collected samples, provided advice on snail culturing and revised the manuscript	collected samples, provided advice on snail culturing and revised the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5839033	29506476	QC	2	designed and constructed the database website, wrote the database section of the manuscript, and revised the manuscript	designed and constructed the database website, wrote the database section of the manuscript, and revised the manuscript	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Software|Writing - Original Draft|Writing - Review & Editing	YES
5839033	29506476	SI	2	collected samples, provided advice on snail culturing and revised the manuscript	collected samples, provided advice on snail culturing and revised the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5839033	29506476	XH	2	designed and constructed the database website, wrote the database section of the manuscript, and revised the manuscript	designed and constructed the database website, wrote the database section of the manuscript, and revised the manuscript	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Software|Writing - Original Draft|Writing - Review & Editing	YES
5845879	29563923	JG	2	supervised the work, helped developing the experiments, revised the manuscript, and contributed to writing	supervised the work, helped developing the experiments, revised the manuscript, and contributed to writing	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
5845879	29563923	MB	2	conducted the experiments, analyzed the data, and wrote the manuscript	conducted the experiments, analyzed the data, and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5845879	29563923	PF	2	supervised the work, helped developing the experiments, revised the manuscript, and contributed to writing	supervised the work, helped developing the experiments, revised the manuscript, and contributed to writing	Performed the experiments|Wrote the paper	Investigation|Supervision|Writing - Original Draft|Writing - Review & Editing	YES
2040219	17971860	DH	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2040219	17971860	DH	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2040219	17971860	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2040219	17971860	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2040219	17971860	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2040219	17971860	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418826	25938462	AP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418826	25938462	ARL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418826	25938462	ARL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418826	25938462	ARL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418826	25938462	COA	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418826	25938462	JM	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418826	25938462	MSRP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418826	25938462	MSRP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418826	25938462	MSRP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418826	25938462	MSRP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4800252	26972716	CL	2	data analysis and interpretation	data analysis and interpretation	Analyzed the data	Formal analysis	YES
4800252	26972716	CQ	2	conception and design of the study|data analysis and interpretation|manuscript drafting|contributed equally to this work	conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4800252	26972716	CQ	2	conception and design of the study|data analysis and interpretation|manuscript drafting|contributed equally to this work	data analysis and interpretation	Analyzed the data	Formal analysis	YES
4800252	26972716	CQ	2	conception and design of the study|data analysis and interpretation|manuscript drafting|contributed equally to this work	manuscript drafting	Wrote the paper	Writing - Original Draft	YES
4800252	26972716	CQ	2	conception and design of the study|data analysis and interpretation|manuscript drafting|contributed equally to this work	contributed equally to this work	-	-	NO
4800252	26972716	HZ	2	conception and design of the study|data acquisition|data analysis and interpretation|manuscript drafting	conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4800252	26972716	HZ	2	conception and design of the study|data acquisition|data analysis and interpretation|manuscript drafting	data acquisition	Performed the experiments	Investigation	YES
4800252	26972716	HZ	2	conception and design of the study|data acquisition|data analysis and interpretation|manuscript drafting	data analysis and interpretation	Analyzed the data	Formal analysis	YES
4800252	26972716	HZ	2	conception and design of the study|data acquisition|data analysis and interpretation|manuscript drafting	manuscript drafting	Wrote the paper	Writing - Original Draft	YES
4800252	26972716	PJ	2	data analysis and interpretation	data analysis and interpretation	Analyzed the data	Formal analysis	YES
4800252	26972716	PL	2	data acquisition	data acquisition	Performed the experiments	Investigation	YES
4800252	26972716	SW	2	data acquisition	data acquisition	Performed the experiments	Investigation	YES
4800252	26972716	YL	2	conception and design of the study|data analysis and interpretation|manuscript drafting|contributed equally to this work	conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4800252	26972716	YL	2	conception and design of the study|data analysis and interpretation|manuscript drafting|contributed equally to this work	data analysis and interpretation	Analyzed the data	Formal analysis	YES
4800252	26972716	YL	2	conception and design of the study|data analysis and interpretation|manuscript drafting|contributed equally to this work	manuscript drafting	Wrote the paper	Writing - Original Draft	YES
4800252	26972716	YL	2	conception and design of the study|data analysis and interpretation|manuscript drafting|contributed equally to this work	contributed equally to this work	-	-	NO
4800252	26972716	all authors	2	have read and approved the final manuscript	have read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6270918	24941341	Bianca Moldovan	2	has been involved in performing the research, analyzing data as well as drafting the paper	has been involved in performing the research, analyzing data as well as drafting the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6270918	24941341	Luminita David	2	as leading author, has been involved in designing the research, interpreting the data, writing and revising the paper	as leading author, has been involved in designing the research, interpreting the data, writing and revising the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
6131683	30203211	All authors	2	discussed the results and contributed to the final manuscript|read and approved the final manuscript	discussed the results and contributed to the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6131683	30203211	All authors	2	discussed the results and contributed to the final manuscript|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6131683	30203211	BE	2	carried out the experiment	carried out the experiment	Performed the experiments	Investigation	YES
6131683	30203211	MHE	2	supervised the project	supervised the project	-	Supervision	YES
6131683	30203211	MM	2	helped supervise the project	helped supervise the project	-	Supervision	YES
5845909	29563919	Both authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
3799581	24014320	ARK	PLoS52	designed the experiments|analysed the data|wrote the paper	designed the experiments	Conceived and designed the experiments	Methodology	YES
3799581	24014320	ARK	PLoS52	designed the experiments|analysed the data|wrote the paper	analysed the data	Analyzed the data	Formal analysis	YES
3799581	24014320	ARK	PLoS52	designed the experiments|analysed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3799581	24014320	All the authors	PLoS52	contributed reagents, protocols, or analysis tools and read and approved the manuscript	contributed reagents, protocols, or analysis tools and read and approved the manuscript	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Methodology|Resources	YES
3799581	24014320	C-PK	PLoS52	designed the experiments|analysed the data|wrote the paper	designed the experiments	Conceived and designed the experiments	Methodology	YES
3799581	24014320	C-PK	PLoS52	designed the experiments|analysed the data|wrote the paper	analysed the data	Analyzed the data	Formal analysis	YES
3799581	24014320	C-PK	PLoS52	designed the experiments|analysed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3799581	24014320	CFB	PLoS52	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
3799581	24014320	DX	PLoS52	performed the experiments|analysed the data	performed the experiments	Performed the experiments	Investigation	YES
3799581	24014320	DX	PLoS52	performed the experiments|analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
3799581	24014320	FR	PLoS52	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
3799581	24014320	GH	PLoS52	performed the experiments|analysed the data	performed the experiments	Performed the experiments	Investigation	YES
3799581	24014320	GH	PLoS52	performed the experiments|analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
3799581	24014320	JEW	PLoS52	performed the experiments|analysed the data	performed the experiments	Performed the experiments	Investigation	YES
3799581	24014320	JEW	PLoS52	performed the experiments|analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
3799581	24014320	KKYL	PLoS52	designed the experiments|performed the experiments|analysed the data|wrote the paper	designed the experiments	Conceived and designed the experiments	Methodology	YES
3799581	24014320	KKYL	PLoS52	designed the experiments|performed the experiments|analysed the data|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
3799581	24014320	KKYL	PLoS52	designed the experiments|performed the experiments|analysed the data|wrote the paper	analysed the data	Analyzed the data	Formal analysis	YES
3799581	24014320	KKYL	PLoS52	designed the experiments|performed the experiments|analysed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3799581	24014320	KS	PLoS52	designed the experiments|performed the experiments|analysed the data|wrote the paper	designed the experiments	Conceived and designed the experiments	Methodology	YES
3799581	24014320	KS	PLoS52	designed the experiments|performed the experiments|analysed the data|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
3799581	24014320	KS	PLoS52	designed the experiments|performed the experiments|analysed the data|wrote the paper	analysed the data	Analyzed the data	Formal analysis	YES
3799581	24014320	KS	PLoS52	designed the experiments|performed the experiments|analysed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3799581	24014320	RZL	PLoS52	designed the experiments|analysed the data	designed the experiments	Conceived and designed the experiments	Methodology	YES
3799581	24014320	RZL	PLoS52	designed the experiments|analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
3799581	24014320	TN	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
3799581	24014320	Y-PJ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
3799581	24014320	YH	PLoS52	designed the experiments|analysed the data	designed the experiments	Conceived and designed the experiments	Methodology	YES
3799581	24014320	YH	PLoS52	designed the experiments|analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
4800253	26972717	ZR	2	coauthored the manuscript, co-designed study and helped in data interpretation, reviewed the histochemical slides, critically reviewed the manuscript for intellectual content	coauthored the manuscript, co-designed study and helped in data interpretation, reviewed the histochemical slides, critically reviewed the manuscript for intellectual content	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
6270919	24786846	Amalia Azzariti	2	deal with the perspective in pancreatic cancer	deal with the perspective in pancreatic cancer	-	-	NO
6270919	24786846	Andreas Gisel	2	deal with the experimental section and bioinformatic analysis	deal with the experimental section and bioinformatic analysis	-	Formal analysis	YES
6270919	24786846	Antonio Carrieri	2	deal with the perspective in pancreatic cancer	deal with the perspective in pancreatic cancer	-	-	NO
6270919	24786846	Imane Ghafir El	2	deal with the perspective in pancreatic cancer	deal with the perspective in pancreatic cancer	-	-	NO
6270919	24786846	Mirna Valvano	2	deal with the experimental section and bioinformatic analysis	deal with the experimental section and bioinformatic analysis	-	Formal analysis	YES
6270919	24786846	Patrizia Nardulli	2	deal with the perspective in pancreatic cancer	deal with the perspective in pancreatic cancer	-	-	NO
2040503	17971872	AF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2040503	17971872	AF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2040503	17971872	AF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2040503	17971872	AF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2040503	17971872	AF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2040503	17971872	AG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2040503	17971872	AG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2040503	17971872	AG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2040503	17971872	CM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2040503	17971872	MB	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2040503	17971872	MV	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2040503	17971872	MV	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2040503	17971872	NG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2040503	17971872	NG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2040503	17971872	NG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5840709	29510660	AJN	2	designed the genome sequencing strategy|contributed to writing the manuscript thereafter	designed the genome sequencing strategy	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5840709	29510660	AJN	2	designed the genome sequencing strategy|contributed to writing the manuscript thereafter	contributed to writing the manuscript thereafter	Wrote the paper	Writing - Original Draft	YES
5840709	29510660	AKT	2	contributed to writing the manuscript thereafter	contributed to writing the manuscript thereafter	Wrote the paper	Writing - Original Draft	YES
5840709	29510660	ATK	2	generated the sequencing libraries and performed the genome sequencing	generated the sequencing libraries and performed the genome sequencing	Performed the experiments	Investigation	YES
5840709	29510660	IR	2	interpreted the data|contributed to writing the manuscript thereafter	interpreted the data	Analyzed the data	Formal analysis	YES
5840709	29510660	IR	2	interpreted the data|contributed to writing the manuscript thereafter	contributed to writing the manuscript thereafter	Wrote the paper	Writing - Original Draft	YES
5840709	29510660	KKL	2	initiated the project|planned and designed the project|performed the sampling|planned the rna seq analysis|performed the rna seq analysis|interpreted the data|finalized the manuscript	initiated the project	Conceived and designed the experiments	Conceptualization	YES
5840709	29510660	KKL	2	initiated the project|planned and designed the project|performed the sampling|planned the rna seq analysis|performed the rna seq analysis|interpreted the data|finalized the manuscript	planned and designed the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5840709	29510660	KKL	2	initiated the project|planned and designed the project|performed the sampling|planned the rna seq analysis|performed the rna seq analysis|interpreted the data|finalized the manuscript	performed the sampling	Performed the experiments	Investigation	YES
5840709	29510660	KKL	2	initiated the project|planned and designed the project|performed the sampling|planned the rna seq analysis|performed the rna seq analysis|interpreted the data|finalized the manuscript	planned the rna seq analysis	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5840709	29510660	KKL	2	initiated the project|planned and designed the project|performed the sampling|planned the rna seq analysis|performed the rna seq analysis|interpreted the data|finalized the manuscript	performed the rna seq analysis	Performed the experiments	Investigation	YES
5840709	29510660	KKL	2	initiated the project|planned and designed the project|performed the sampling|planned the rna seq analysis|performed the rna seq analysis|interpreted the data|finalized the manuscript	interpreted the data	Analyzed the data	Formal analysis	YES
5840709	29510660	KKL	2	initiated the project|planned and designed the project|performed the sampling|planned the rna seq analysis|performed the rna seq analysis|interpreted the data|finalized the manuscript	finalized the manuscript	Wrote the paper	Writing - Review & Editing	YES
5840709	29510660	MHS	2	planned the rna seq analysis|performed the rna seq analysis|contributed to writing the manuscript thereafter	planned the rna seq analysis	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5840709	29510660	MHS	2	planned the rna seq analysis|performed the rna seq analysis|contributed to writing the manuscript thereafter	performed the rna seq analysis	Performed the experiments	Investigation	YES
5840709	29510660	MHS	2	planned the rna seq analysis|performed the rna seq analysis|contributed to writing the manuscript thereafter	contributed to writing the manuscript thereafter	Wrote the paper	Writing - Original Draft	YES
5840709	29510660	OKT	2	established and ran the genome assembly and annotation pipeline|designed the genome sequencing strategy|contributed to writing the manuscript thereafter	established and ran the genome assembly and annotation pipeline	Performed the experiments|Analyzed the data	Data curation|Formal analysis|Investigation	YES
5840709	29510660	OKT	2	established and ran the genome assembly and annotation pipeline|designed the genome sequencing strategy|contributed to writing the manuscript thereafter	designed the genome sequencing strategy	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5840709	29510660	OKT	2	established and ran the genome assembly and annotation pipeline|designed the genome sequencing strategy|contributed to writing the manuscript thereafter	contributed to writing the manuscript thereafter	Wrote the paper	Writing - Original Draft	YES
5840709	29510660	OS	2	initiated the project|planned and designed the project|performed the sampling|interpreted the data|contributed to writing the manuscript thereafter|finalized the manuscript	initiated the project	Conceived and designed the experiments	Conceptualization	YES
5840709	29510660	OS	2	initiated the project|planned and designed the project|performed the sampling|interpreted the data|contributed to writing the manuscript thereafter|finalized the manuscript	planned and designed the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5840709	29510660	OS	2	initiated the project|planned and designed the project|performed the sampling|interpreted the data|contributed to writing the manuscript thereafter|finalized the manuscript	performed the sampling	Performed the experiments	Investigation	YES
5840709	29510660	OS	2	initiated the project|planned and designed the project|performed the sampling|interpreted the data|contributed to writing the manuscript thereafter|finalized the manuscript	interpreted the data	Analyzed the data	Formal analysis	YES
5840709	29510660	OS	2	initiated the project|planned and designed the project|performed the sampling|interpreted the data|contributed to writing the manuscript thereafter|finalized the manuscript	contributed to writing the manuscript thereafter	Wrote the paper	Writing - Original Draft	YES
5840709	29510660	OS	2	initiated the project|planned and designed the project|performed the sampling|interpreted the data|contributed to writing the manuscript thereafter|finalized the manuscript	finalized the manuscript	Wrote the paper	Writing - Review & Editing	YES
5840709	29510660	SJ	2	planned and designed the project|planned the rna seq analysis|designed the genome sequencing strategy|interpreted the data|contributed to writing the manuscript thereafter|finalized the manuscript	planned and designed the project	Conceived and designed the experiments	Conceptualization|Methodology	YES
5840709	29510660	SJ	2	planned and designed the project|planned the rna seq analysis|designed the genome sequencing strategy|interpreted the data|contributed to writing the manuscript thereafter|finalized the manuscript	planned the rna seq analysis	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
5840709	29510660	SJ	2	planned and designed the project|planned the rna seq analysis|designed the genome sequencing strategy|interpreted the data|contributed to writing the manuscript thereafter|finalized the manuscript	designed the genome sequencing strategy	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5840709	29510660	SJ	2	planned and designed the project|planned the rna seq analysis|designed the genome sequencing strategy|interpreted the data|contributed to writing the manuscript thereafter|finalized the manuscript	interpreted the data	Analyzed the data	Formal analysis	YES
5840709	29510660	SJ	2	planned and designed the project|planned the rna seq analysis|designed the genome sequencing strategy|interpreted the data|contributed to writing the manuscript thereafter|finalized the manuscript	contributed to writing the manuscript thereafter	Wrote the paper	Writing - Original Draft	YES
5840709	29510660	SJ	2	planned and designed the project|planned the rna seq analysis|designed the genome sequencing strategy|interpreted the data|contributed to writing the manuscript thereafter|finalized the manuscript	finalized the manuscript	Wrote the paper	Writing - Review & Editing	YES
4418827	25938761	CAC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4418827	25938761	CAC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418827	25938761	CWC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418827	25938761	CWC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418827	25938761	CWC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418827	25938761	CWC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418827	25938761	CWC	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418827	25938761	CYC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418827	25938761	CYC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418827	25938761	CYC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418827	25938761	MSW	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418827	25938761	MSW	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418827	25938761	MSW	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418827	25938761	YJH	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4418827	25938761	YJH	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5846014	29563922	All authors	2	listed have made a substantial, direct and intellectual contribution to the work, and approved it for publication	listed have made a substantial, direct and intellectual contribution to the work, and approved it for publication	-	-	NO
5846014	29563922	The authors	2	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	Performed the experiments	Investigation	YES
4322447	25563976	S These	2	authors contributed equally	authors contributed equally	-	-	NO
5832686	29483346	B.A.	2	contributed to the conception and design of this review, making decisions about inclusion criteria for articles, interpretation of the data, drafting and revising the article, and final approval of the version to be published	contributed to the conception and design of this review, making decisions about inclusion criteria for articles, interpretation of the data, drafting and revising the article, and final approval of the version to be published	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5832686	29483346	D.J.	2	contributed to gathering and organizing research articles for the review, drafting and organizing the tables, and revising the article	contributed to gathering and organizing research articles for the review, drafting and organizing the tables, and revising the article	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5832686	29483346	E.A.	2	contributed to making decisions about the inclusion criteria and revising the article	contributed to making decisions about the inclusion criteria and revising the article	Wrote the paper	Writing - Review & Editing	YES
5832686	29483346	PhD	2	contributed to the conception and design of this review, making decisions about inclusion criteria for articles, interpretation of the data, drafting and revising the article, and final approval of the version to be published|contributed to making decisions about the inclusion criteria and revising the article	contributed to the conception and design of this review, making decisions about inclusion criteria for articles, interpretation of the data, drafting and revising the article, and final approval of the version to be published	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Resources|Writing - Original Draft|Writing - Review & Editing	YES
5832686	29483346	PhD	2	contributed to the conception and design of this review, making decisions about inclusion criteria for articles, interpretation of the data, drafting and revising the article, and final approval of the version to be published|contributed to making decisions about the inclusion criteria and revising the article	contributed to making decisions about the inclusion criteria and revising the article	Wrote the paper	Writing - Review & Editing	YES
5832686	29483346	S.P.	2	contributed to gathering and organizing research articles for the review, drafting and organizing the tables, and revising the article	contributed to gathering and organizing research articles for the review, drafting and organizing the tables, and revising the article	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4800254	26972718	FB	2	technical analysis, partial manuscript revision	technical analysis, partial manuscript revision	Wrote the paper	Writing - Review & Editing	YES
4800254	26972718	GTS	2	manuscript language and stylistics, partial manuscript revision	manuscript language and stylistics, partial manuscript revision	Wrote the paper	Writing - Review & Editing	YES
4800254	26972718	JW	2	final data analysis, final manuscript revision	final data analysis, final manuscript revision	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4800254	26972718	LLM	2	interpretation of analysis results, statistical study	interpretation of analysis results, statistical study	Analyzed the data	Formal analysis	YES
4800254	26972718	MASP	2	protocol and data analysis, preparation, interpretation of analysis results, manuscript revision	protocol and data analysis, preparation, interpretation of analysis results, manuscript revision	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
4800254	26972718	RLS	2	technical analysis	technical analysis	-	-	NO
4800254	26972718	TRT	2	technical analysis, data analysis	technical analysis, data analysis	Analyzed the data	Formal analysis	YES
6270920	24818575	Georgina Alarcon-Angeles	2	carried out the electrochemical experiments|participated in the analysis and discussion of results and the developed of the theoretical model used	carried out the electrochemical experiments	Performed the experiments	Investigation	YES
6270920	24818575	Georgina Alarcon-Angeles	2	carried out the electrochemical experiments|participated in the analysis and discussion of results and the developed of the theoretical model used	participated in the analysis and discussion of results and the developed of the theoretical model used	Performed the experiments|Analyzed the data	Formal analysis|Methodology	YES
6270920	24818575	Manuel Palomar-Pardave	2	participated in the conception and design of the study|participated in the analysis and discussion of results and the developed of the theoretical model used	participated in the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6270920	24818575	Manuel Palomar-Pardave	2	participated in the conception and design of the study|participated in the analysis and discussion of results and the developed of the theoretical model used	participated in the analysis and discussion of results and the developed of the theoretical model used	Performed the experiments|Analyzed the data	Formal analysis|Methodology	YES
6270920	24818575	Mario Romero-Romo	2	participated in the conception and design of the study|participated in the analysis and discussion of results and the developed of the theoretical model used	participated in the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6270920	24818575	Mario Romero-Romo	2	participated in the conception and design of the study|participated in the analysis and discussion of results and the developed of the theoretical model used	participated in the analysis and discussion of results and the developed of the theoretical model used	Performed the experiments|Analyzed the data	Formal analysis|Methodology	YES
6270920	24818575	Silvia Corona-Avendano	2	carried out the electrochemical experiments|participated in the analysis and discussion of results and the developed of the theoretical model used	carried out the electrochemical experiments	Performed the experiments	Investigation	YES
6270920	24818575	Silvia Corona-Avendano	2	carried out the electrochemical experiments|participated in the analysis and discussion of results and the developed of the theoretical model used	participated in the analysis and discussion of results and the developed of the theoretical model used	Performed the experiments|Analyzed the data	Formal analysis|Methodology	YES
6270920	24818575	Teresa Ramirez-Silva	2	participated in the analysis and discussion of results and the developed of the theoretical model used	participated in the analysis and discussion of results and the developed of the theoretical model used	Performed the experiments|Analyzed the data	Formal analysis|Methodology	YES
2040504	17971873	CL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2040504	17971873	CL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2040504	17971873	CL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2040504	17971873	CL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2040504	17971873	FA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2040504	17971873	FA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2040504	17971873	FA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2040504	17971873	FB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2040504	17971873	FB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
2040504	17971873	FB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
2040504	17971873	FB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2040504	17971873	HL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2040504	17971873	HL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2040504	17971873	HL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2040504	17971873	HL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2040504	17971873	PG	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2040504	17971873	PG	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2040504	17971873	PR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2040504	17971873	PR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
2040504	17971873	PR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2040504	17971873	RS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2040504	17971873	RS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
2040504	17971873	RS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
3799582	24009212	CHJ	PLoS52	conducted western blots	conducted western blots	Performed the experiments	Investigation	YES
3799582	24009212	HL	PLoS52	performed the cell and animal studies	performed the cell and animal studies	Performed the experiments	Investigation	YES
3799582	24009212	JA	PLoS52	designed the experiments and wrote the paper|performed the cell and animal studies|analysed the data	designed the experiments and wrote the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3799582	24009212	JA	PLoS52	designed the experiments and wrote the paper|performed the cell and animal studies|analysed the data	performed the cell and animal studies	Performed the experiments	Investigation	YES
3799582	24009212	JA	PLoS52	designed the experiments and wrote the paper|performed the cell and animal studies|analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
3799582	24009212	TH	PLoS52	designed the experiments and wrote the paper	designed the experiments and wrote the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3799582	24009212	TIJ	PLoS52	analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
6134474	30203150	All	PLoS52	data analyzed in this article are included in the figures and tables	data analyzed in this article are included in the figures and tables	Analyzed the data	Formal analysis|Visualization	YES
6134474	30203150	All authors	PLoS52	reviewed the results|read and approved the final manuscript	reviewed the results	-	-	NO
6134474	30203150	All authors	PLoS52	reviewed the results|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6134474	30203150	FXS	PLoS52	designed the study and wrote the paper|performed the experiments	designed the study and wrote the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
6134474	30203150	FXS	PLoS52	designed the study and wrote the paper|performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
6134474	30203150	The authors	PLoS52	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
6134474	30203150	WYL	PLoS52	conceived project|designed the study and wrote the paper|performed the experiments	conceived project	Conceived and designed the experiments	Conceptualization	YES
6134474	30203150	WYL	PLoS52	conceived project|designed the study and wrote the paper|performed the experiments	designed the study and wrote the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
6134474	30203150	WYL	PLoS52	conceived project|designed the study and wrote the paper|performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
6134474	30203150	YH	PLoS52	conceived project|designed the study and wrote the paper|revised the english language	conceived project	Conceived and designed the experiments	Conceptualization	YES
6134474	30203150	YH	PLoS52	conceived project|designed the study and wrote the paper|revised the english language	designed the study and wrote the paper	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
6134474	30203150	YH	PLoS52	conceived project|designed the study and wrote the paper|revised the english language	revised the english language	Wrote the paper	Writing - Review & Editing	YES
5846053	29563924	DQ	2	assisted the experiments	assisted the experiments	Performed the experiments	Investigation	YES
5846053	29563924	HZ	2	assisted the experiments	assisted the experiments	Performed the experiments	Investigation	YES
5846053	29563924	JY	2	assisted the experiments	assisted the experiments	Performed the experiments	Investigation	YES
5846053	29563924	LG	2	assisted the experiments	assisted the experiments	Performed the experiments	Investigation	YES
5846053	29563924	SC	2	carried out the experiments and wrote the manuscript	carried out the experiments and wrote the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5846053	29563924	XT	2	analyzed the experimental results	analyzed the experimental results	Analyzed the data	Formal analysis	YES
5846053	29563924	XY	2	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
5846053	29563924	YL	2	carried out the experiments and wrote the manuscript	carried out the experiments and wrote the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5846053	29563924	YZ	2	assisted the experiments	assisted the experiments	Performed the experiments	Investigation	YES
4418828	25938453	BF	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418828	25938453	BF	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418828	25938453	BL	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418828	25938453	JBP	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418828	25938453	JBP	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418828	25938453	MM	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418828	25938453	SF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418828	25938453	SF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418828	25938453	SF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418828	25938453	SMC	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418828	25938453	SMC	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5797391	29435329	PP	2	designed the study, performed the ultrasound examinations and the statistical analysis, and drafted the manuscript	designed the study, performed the ultrasound examinations and the statistical analysis, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5797391	29435329	SR	2	designed the study, performed the ultrasound examinations and the statistical analysis, and drafted the manuscript	designed the study, performed the ultrasound examinations and the statistical analysis, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5840728	29510661	CH	7	Collection and assembly of data, Data analysis and interpretation	Collection and assembly of data, Data analysis and interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5840728	29510661	DH	7	Collection and assembly of data, Data analysis and interpretation	Collection and assembly of data, Data analysis and interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5840728	29510661	JD	7	Collection and assembly of data, Data analysis and interpretation	Collection and assembly of data, Data analysis and interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5840728	29510661	JW	7	Conception and design, Data analysis and interpretation	Conception and design, Data analysis and interpretation	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
5840728	29510661	KV	7	Collection and assembly of data	Collection and assembly of data	Performed the experiments	Investigation	YES
5840728	29510661	LW	7	Collection and assembly of data, Data analysis and interpretation, Manuscript writing	Collection and assembly of data, Data analysis and interpretation, Manuscript writing	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5840728	29510661	MZ	7	Conception and design, Data analysis and interpretation	Conception and design, Data analysis and interpretation	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis	YES
5840728	29510661	SS	7	Collection and assembly of data	Collection and assembly of data	Performed the experiments	Investigation	YES
5840728	29510661	XT	7	Conception and design, Financial support, Collection and assembly of data, Data analysis and interpretation, Manuscript writing	Conception and design, Financial support, Collection and assembly of data, Data analysis and interpretation, Manuscript writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Funding acquisition|Investigation|Writing - Original Draft	YES
5840728	29510661	YT	7	Conception and design, Financial support, Collection and assembly of data, Data analysis and interpretation, Manuscript writing	Conception and design, Financial support, Collection and assembly of data, Data analysis and interpretation, Manuscript writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Funding acquisition|Investigation|Writing - Original Draft	YES
5840728	29510661	YY	7	Collection and assembly of data	Collection and assembly of data	Performed the experiments	Investigation	YES
5840728	29510661	ZJ	7	Collection and assembly of data, Data analysis and interpretation, Manuscript writing	Collection and assembly of data, Data analysis and interpretation, Manuscript writing	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4800255	26972719	ADA	2	study design, coordination, manuscript drafting|contributed equally to this work	study design, coordination, manuscript drafting	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft	YES
4800255	26972719	ADA	2	study design, coordination, manuscript drafting|contributed equally to this work	contributed equally to this work	-	-	NO
4800255	26972719	AV	2	study design, coordination, manuscript drafting|contributed equally to this work	study design, coordination, manuscript drafting	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft	YES
4800255	26972719	AV	2	study design, coordination, manuscript drafting|contributed equally to this work	contributed equally to this work	-	-	NO
4800255	26972719	DZ	2	surgical specimens providing	surgical specimens providing	Performed the experiments	Investigation	YES
4800255	26972719	EG	2	study supervision, critical manuscript revision	study supervision, critical manuscript revision	Wrote the paper	Supervision|Writing - Review & Editing	YES
4800255	26972719	FP	2	surgical specimens providing	surgical specimens providing	Performed the experiments	Investigation	YES
4800255	26972719	GC	2	study supervision, critical manuscript revision	study supervision, critical manuscript revision	Wrote the paper	Supervision|Writing - Review & Editing	YES
4800255	26972719	RS	2	immunohistochemical analyses performing, participation in the study design	immunohistochemical analyses performing, participation in the study design	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
4800255	26972719	SP	2	immunohistochemical and immunofluorescence analyses performing	immunohistochemical and immunofluorescence analyses performing	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5832687	29483347	All authors	2	gave final approval for publication	gave final approval for publication	-	-	NO
5832687	29483347	G.D.S.	2	critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5832687	29483347	H.S.	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5832687	29483347	M.R.M.	2	critically revised the manuscript	critically revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
6270921	25412045	AM	PLoS52	performed research and analyzed the data	performed research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270921	25412045	AO	PLoS52	performed research and analyzed the data	performed research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270921	25412045	CB	PLoS52	performed research and analyzed the data	performed research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270921	25412045	GT	PLoS52	performed research and analyzed the data	performed research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270921	25412045	HC	PLoS52	performed research and analyzed the data	performed research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270921	25412045	IM	PLoS52	designed research|performed research and analyzed the data|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
6270921	25412045	IM	PLoS52	designed research|performed research and analyzed the data|wrote the paper	performed research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270921	25412045	IM	PLoS52	designed research|performed research and analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270921	25412045	JV	PLoS52	designed research|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
6270921	25412045	JV	PLoS52	designed research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270921	25412045	MC	PLoS52	designed research|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
6270921	25412045	MC	PLoS52	designed research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270921	25412045	NQ	PLoS52	performed research and analyzed the data	performed research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270921	25412045	RM	PLoS52	performed research and analyzed the data	performed research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
2040505	17987111	DH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2040505	17987111	DH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2040505	17987111	DH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2040505	17987111	DH	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2040505	17987111	HL	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2040505	17987111	KT	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2040505	17987111	KT	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2040505	17987111	KT	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2040505	17987111	LH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
2040505	17987111	NV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2040505	17987111	NV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2040505	17987111	NV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2040505	17987111	NV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2040505	17987111	SL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2040505	17987111	SL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2040505	17987111	SL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6134574	30203194	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6134574	30203194	D. Kim	2	and 2018r1d1a1b07049569	and 2018r1d1a1b07049569	-	-	NO
6134574	30203194	DK	2	designed and coordinated the study	designed and coordinated the study	Conceived and designed the experiments	Methodology|Project administration	YES
6134574	30203194	JH	2	performed fermentation and morphological characterization|drafted manuscript	performed fermentation and morphological characterization	Performed the experiments	Investigation	YES
6134574	30203194	JH	2	performed fermentation and morphological characterization|drafted manuscript	drafted manuscript	Wrote the paper	Writing - Original Draft	YES
6134574	30203194	JK	2	performed preparation of extracts and component analyses	performed preparation of extracts and component analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6134574	30203194	NP	2	performed preparation of extracts and component analyses	performed preparation of extracts and component analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6134574	30203194	TN	2	carried out antioxidant assay and cell test|drafted manuscript	carried out antioxidant assay and cell test	Performed the experiments	Investigation	YES
6134574	30203194	TN	2	carried out antioxidant assay and cell test|drafted manuscript	drafted manuscript	Wrote the paper	Writing - Original Draft	YES
6134574	30203194	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5850050	29563920	AB	2	collected data	collected data	Performed the experiments	Investigation	YES
5850050	29563920	ES	2	built the pteridaceae phylogeny	built the pteridaceae phylogeny	-	-	NO
5850050	29563920	JM	2	co-designed the study and collected data	co-designed the study and collected data	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5850050	29563920	NR	2	provided critical analytical tools, insights and comments on the manuscript	provided critical analytical tools, insights and comments on the manuscript	Contributed reagents/materials/analysis tools	Resources	YES
5800039	29445502	All authors	2	contributed to the analysis and interpretation of the study and revised and drafted the manuscript	contributed to the analysis and interpretation of the study and revised and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
5800039	29445502	KH	2	conceived and designed the study|collected the data of the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5800039	29445502	KH	2	conceived and designed the study|collected the data of the study	collected the data of the study	Performed the experiments	Investigation	YES
5800039	29445502	LD	2	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5800039	29445502	SB	2	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3799583	24014289	AS	2	analyzed mir-132-3p targets	analyzed mir-132-3p targets	Analyzed the data	Formal analysis	YES
3799583	24014289	All co-authors	2	provided discussion, data interpretation and contributed to the final version of the manuscript	provided discussion, data interpretation and contributed to the final version of the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
3799583	24014289	BDS	2	conceived the study, performed data analysis and wrote the manuscript	conceived the study, performed data analysis and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
3799583	24014289	CSF	2	performed real time pcr and western-blot experiments	performed real time pcr and western-blot experiments	Performed the experiments	Investigation	YES
3799583	24014289	DG	2	acquired temporal gyrus samples from the netherlands brain bank and analyzed real time pcr data	acquired temporal gyrus samples from the netherlands brain bank and analyzed real time pcr data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3799583	24014289	DS	2	supervised the helped in the ncounter data analysis and the writing of the manuscript under the	supervised the helped in the ncounter data analysis and the writing of the manuscript under the	Analyzed the data|Wrote the paper	Formal analysis|Supervision|Writing - Original Draft	YES
3799583	24014289	ES	2	performed luciferase assays	performed luciferase assays	Performed the experiments	Investigation	YES
3799583	24014289	HS	2	acquired temporal gyrus samples from the netherlands brain bank and analyzed real time pcr data	acquired temporal gyrus samples from the netherlands brain bank and analyzed real time pcr data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3799583	24014289	JV	2	supervised the helped in the ncounter data analysis and the writing of the manuscript under the	supervised the helped in the ncounter data analysis and the writing of the manuscript under the	Analyzed the data|Wrote the paper	Formal analysis|Supervision|Writing - Original Draft	YES
3799583	24014289	KB	2	obtained samples from the netherlands brain bank, performed in situ experiments, helped in the ncounter data analysis and the writing of the manuscript under the	obtained samples from the netherlands brain bank, performed in situ experiments, helped in the ncounter data analysis and the writing of the manuscript under the	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3799583	24014289	PL	2	conceived the study, performed data analysis and wrote the manuscript	conceived the study, performed data analysis and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Writing - Original Draft	YES
3799583	24014289	RJ	2	performed deep-sequencing data	performed deep-sequencing data	Performed the experiments	Investigation	YES
3799583	24014289	RNA	2	editing and regulatory analyses	editing and regulatory analyses	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
3799583	24014289	RR	2	acquired temporal gyrus samples from the netherlands brain bank and analyzed real time pcr data	acquired temporal gyrus samples from the netherlands brain bank and analyzed real time pcr data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3799583	24014289	SA	2	performed deep-sequencing data	performed deep-sequencing data	Performed the experiments	Investigation	YES
3799583	24014289	SB	2	acquired temporal gyrus samples from the netherlands brain bank and analyzed real time pcr data	acquired temporal gyrus samples from the netherlands brain bank and analyzed real time pcr data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3799583	24014289	SP	2	analyzed mir-132-3p targets	analyzed mir-132-3p targets	Analyzed the data	Formal analysis	YES
3799583	24014289	TA	2	analyzed mir-132-3p targets|supervised deep-sequencing experiment	analyzed mir-132-3p targets	Analyzed the data	Formal analysis	YES
3799583	24014289	TA	2	analyzed mir-132-3p targets|supervised deep-sequencing experiment	supervised deep-sequencing experiment	Performed the experiments	Investigation|Supervision	YES
6270922	24448062	Hong-Rui Chen	2	conducted the study and collected the data|analyzed the data and wrote the manuscript	conducted the study and collected the data	Performed the experiments	Investigation	YES
6270922	24448062	Hong-Rui Chen	2	conducted the study and collected the data|analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6270922	24448062	Hong-Xun Zhang	2	participated in designing the study	participated in designing the study	Conceived and designed the experiments	Methodology	YES
6270922	24448062	Jing Wang	2	conducted the study and collected the data	conducted the study and collected the data	Performed the experiments	Investigation	YES
6270922	24448062	Ling-Hui Sheng	2	conducted the study and collected the data|analyzed the data and wrote the manuscript	conducted the study and collected the data	Performed the experiments	Investigation	YES
6270922	24448062	Ling-Hui Sheng	2	conducted the study and collected the data|analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6270922	24448062	Min Yang	2	participated in designing the study	participated in designing the study	Conceived and designed the experiments	Methodology	YES
6270922	24448062	Ying-Bin Huo	2	conducted the study and collected the data	conducted the study and collected the data	Performed the experiments	Investigation	YES
6270922	24448062	Yu Zhang	2	participated in designing the study	participated in designing the study	Conceived and designed the experiments	Methodology	YES
4933822	27349311	AA	2	collection of biopsies	collection of biopsies	Performed the experiments	Investigation	YES
4933822	27349311	AC	2	experimental procedures, immunohistochemical processing	experimental procedures, immunohistochemical processing	Performed the experiments	Investigation	YES
4933822	27349311	AF	2	collection of biopsies|microscopic analysis, data collection and/or preparation of figures	collection of biopsies	Performed the experiments	Investigation	YES
4933822	27349311	AF	2	collection of biopsies|microscopic analysis, data collection and/or preparation of figures	microscopic analysis, data collection and/or preparation of figures	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
4933822	27349311	All authors	2	have reviewed and contributed to the different draft versions of the manuscript and have read and approved the final manuscript	have reviewed and contributed to the different draft versions of the manuscript and have read and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4933822	27349311	BF	2	collection of biopsies	collection of biopsies	Performed the experiments	Investigation	YES
4933822	27349311	FS	2	experimental procedures, immunohistochemical processing	experimental procedures, immunohistochemical processing	Performed the experiments	Investigation	YES
4933822	27349311	FT	2	study design|microscopic analysis, data collection and/or preparation of figures	study design	Conceived and designed the experiments	Methodology	YES
4933822	27349311	FT	2	study design|microscopic analysis, data collection and/or preparation of figures	microscopic analysis, data collection and/or preparation of figures	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
4933822	27349311	GC	2	study design|experimental procedures, immunohistochemical processing|microscopic analysis, data collection and/or preparation of figures	study design	Conceived and designed the experiments	Methodology	YES
4933822	27349311	GC	2	study design|experimental procedures, immunohistochemical processing|microscopic analysis, data collection and/or preparation of figures	experimental procedures, immunohistochemical processing	Performed the experiments	Investigation	YES
4933822	27349311	GC	2	study design|experimental procedures, immunohistochemical processing|microscopic analysis, data collection and/or preparation of figures	microscopic analysis, data collection and/or preparation of figures	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
4933822	27349311	GR	2	experimental procedures, immunohistochemical processing	experimental procedures, immunohistochemical processing	Performed the experiments	Investigation	YES
4933822	27349311	GV	2	experimental procedures, immunohistochemical processing|microscopic analysis, data collection and/or preparation of figures	experimental procedures, immunohistochemical processing	Performed the experiments	Investigation	YES
4933822	27349311	GV	2	experimental procedures, immunohistochemical processing|microscopic analysis, data collection and/or preparation of figures	microscopic analysis, data collection and/or preparation of figures	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
4933822	27349311	MGP	2	study design	study design	Conceived and designed the experiments	Methodology	YES
4933822	27349311	MR	2	collection of biopsies|microscopic analysis, data collection and/or preparation of figures	collection of biopsies	Performed the experiments	Investigation	YES
4933822	27349311	MR	2	collection of biopsies|microscopic analysis, data collection and/or preparation of figures	microscopic analysis, data collection and/or preparation of figures	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
4933822	27349311	PB	2	study design	study design	Conceived and designed the experiments	Methodology	YES
4933822	27349311	RG	2	study design	study design	Conceived and designed the experiments	Methodology	YES
2040506	17971864	AB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
2040506	17971864	AE	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2040506	17971864	AE	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2040506	17971864	AL	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2040506	17971864	CD	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
2040506	17971864	CF	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2040506	17971864	DG	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2040506	17971864	DG	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
2040506	17971864	KT	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
2040506	17971864	MC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2040506	17971864	TG	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
2040506	17971864	TG	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2040506	17971864	UD	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2040506	17971864	UD	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5840783	29510674	HJT	2	contributed sampling and/or lab work|contributed to statistical analyses and production of the paper	contributed sampling and/or lab work	Performed the experiments	Investigation	YES
5840783	29510674	HJT	2	contributed sampling and/or lab work|contributed to statistical analyses and production of the paper	contributed to statistical analyses and production of the paper	Analyzed the data	Formal analysis	YES
5840783	29510674	LXZ	2	contributed sampling and/or lab work	contributed sampling and/or lab work	Performed the experiments	Investigation	YES
5840783	29510674	RPB	2	contributed to statistical analyses and production of the paper	contributed to statistical analyses and production of the paper	Analyzed the data	Formal analysis	YES
5840783	29510674	SS	2	contributed sampling and/or lab work	contributed sampling and/or lab work	Performed the experiments	Investigation	YES
5840783	29510674	YBW	2	contributed sampling and/or lab work	contributed sampling and/or lab work	Performed the experiments	Investigation	YES
5840783	29510674	YTJ	2	contributed sampling and/or lab work|contributed to statistical analyses and production of the paper	contributed sampling and/or lab work	Performed the experiments	Investigation	YES
5840783	29510674	YTJ	2	contributed sampling and/or lab work|contributed to statistical analyses and production of the paper	contributed to statistical analyses and production of the paper	Analyzed the data	Formal analysis	YES
4673327	26688823	Abelardo Aguilera	2	contributed equally to this work	contributed equally to this work	-	-	NO
4673327	26688823	Anna Rita Aguirre	2	contributed equally to this work	contributed equally to this work	-	-	NO
4673327	26688823	Georgios Liappas	2	contributed equally to this work	contributed equally to this work	-	-	NO
4673327	26688823	Tirma Gonzalez-Mateo	2	contributed equally to this work	contributed equally to this work	-	-	NO
4418829	25938414	CS	PLoS5	Conceived and designed the experiments|Reviewed and revised drafts of manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418829	25938414	CS	PLoS5	Conceived and designed the experiments|Reviewed and revised drafts of manuscript	Reviewed and revised drafts of manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4418829	25938414	DK	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418829	25938414	DK	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418829	25938414	DK	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418829	25938414	JDM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418829	25938414	JDM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418829	25938414	JDM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418829	25938414	JDM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418829	25938414	MY	PLoS5	Conceived and designed the experiments|Reviewed and revised drafts of manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418829	25938414	MY	PLoS5	Conceived and designed the experiments|Reviewed and revised drafts of manuscript	Reviewed and revised drafts of manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4418829	25938414	SE	PLoS5	Performed the experiments|Reviewed and revised drafts of manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4418829	25938414	SE	PLoS5	Performed the experiments|Reviewed and revised drafts of manuscript	Reviewed and revised drafts of manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4418829	25938414	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Reviewed and revised drafts of manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418829	25938414	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Reviewed and revised drafts of manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4418829	25938414	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Reviewed and revised drafts of manuscript	Reviewed and revised drafts of manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6270923	25397737	HO	PLoS52	performed the research and analyzed the data	performed the research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270923	25397737	JB	PLoS52	performed the research and analyzed the data	performed the research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270923	25397737	JK	PLoS52	performed the research and analyzed the data|wrote the paper	performed the research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270923	25397737	JK	PLoS52	performed the research and analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270923	25397737	JO	PLoS52	designed the research|wrote the paper	designed the research	Conceived and designed the experiments	Methodology	YES
6270923	25397737	JO	PLoS52	designed the research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270923	25397737	ML	PLoS52	designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
6270923	25397737	MR	PLoS52	designed the research|wrote the paper	designed the research	Conceived and designed the experiments	Methodology	YES
6270923	25397737	MR	PLoS52	designed the research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270923	25397737	SK	PLoS52	performed the research and analyzed the data|wrote the paper	performed the research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270923	25397737	SK	PLoS52	performed the research and analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270923	25397737	SP	PLoS52	performed the research and analyzed the data|wrote the paper	performed the research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270923	25397737	SP	PLoS52	performed the research and analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5813360	29468069	CYL	2	contributed to the analysis and interpretation|drafted the manuscript for important intellectual content	contributed to the analysis and interpretation	Analyzed the data	Formal analysis	YES
5813360	29468069	CYL	2	contributed to the analysis and interpretation|drafted the manuscript for important intellectual content	drafted the manuscript for important intellectual content	Wrote the paper	Writing - Original Draft	YES
5813360	29468069	DL	2	contributed to the analysis and interpretation|drafted the manuscript for important intellectual content	contributed to the analysis and interpretation	Analyzed the data	Formal analysis	YES
5813360	29468069	DL	2	contributed to the analysis and interpretation|drafted the manuscript for important intellectual content	drafted the manuscript for important intellectual content	Wrote the paper	Writing - Original Draft	YES
5813360	29468069	KCL	2	contributed to the analysis and interpretation|drafted the manuscript for important intellectual content	contributed to the analysis and interpretation	Analyzed the data	Formal analysis	YES
5813360	29468069	KCL	2	contributed to the analysis and interpretation|drafted the manuscript for important intellectual content	drafted the manuscript for important intellectual content	Wrote the paper	Writing - Original Draft	YES
5813360	29468069	NVVC	2	contributed to the analysis and interpretation|drafted the manuscript for important intellectual content	contributed to the analysis and interpretation	Analyzed the data	Formal analysis	YES
5813360	29468069	NVVC	2	contributed to the analysis and interpretation|drafted the manuscript for important intellectual content	drafted the manuscript for important intellectual content	Wrote the paper	Writing - Original Draft	YES
5813360	29468069	SEAICRN	2	executive committee conceived and supervised the study|executive committee contributed to the conception and design	executive committee conceived and supervised the study	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Supervision	YES
5813360	29468069	SEAICRN	2	executive committee conceived and supervised the study|executive committee contributed to the conception and design	executive committee contributed to the conception and design	Conceived and designed the experiments	Conceptualization	YES
5813360	29468069	TEW	2	contributed to the analysis and interpretation|drafted the manuscript for important intellectual content	contributed to the analysis and interpretation	Analyzed the data	Formal analysis	YES
5813360	29468069	TEW	2	contributed to the analysis and interpretation|drafted the manuscript for important intellectual content	drafted the manuscript for important intellectual content	Wrote the paper	Writing - Original Draft	YES
5850829	29563921	L-HL	2	prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5850829	29563921	T-FF	2	prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
6143494	30229415	APG	CRediT	Data curation|Writing|Validation	Data curation	Analyzed the data	Data curation	YES
6143494	30229415	APG	CRediT	Data curation|Writing|Validation	Writing	Wrote the paper	-	YES
6143494	30229415	APG	CRediT	Data curation|Writing|Validation	Validation	Performed the experiments	Validation	YES
6143494	30229415	DCZ	CRediT	Data curation|Funding|Validation|Review & editing	Data curation	Analyzed the data	Data curation	YES
6143494	30229415	DCZ	CRediT	Data curation|Funding|Validation|Review & editing	Funding	-	Funding acquisition	YES
6143494	30229415	DCZ	CRediT	Data curation|Funding|Validation|Review & editing	Validation	Performed the experiments	Validation	YES
6143494	30229415	DCZ	CRediT	Data curation|Funding|Validation|Review & editing	Review & editing	Wrote the paper	Writing - Review & Editing	YES
6143494	30229415	GMP	CRediT	Funding|Validation	Funding	-	Funding acquisition	YES
6143494	30229415	GMP	CRediT	Funding|Validation	Validation	Performed the experiments	Validation	YES
6143494	30229415	JC	CRediT	Conceptualization|Literature review|Data curation|Writing|Funding|Validation|Review & editing	Conceptualization	Conceived and designed the experiments	Conceptualization	YES
6143494	30229415	JC	CRediT	Conceptualization|Literature review|Data curation|Writing|Funding|Validation|Review & editing	Literature review	-	Formal analysis	YES
6143494	30229415	JC	CRediT	Conceptualization|Literature review|Data curation|Writing|Funding|Validation|Review & editing	Data curation	Analyzed the data	Data curation	YES
6143494	30229415	JC	CRediT	Conceptualization|Literature review|Data curation|Writing|Funding|Validation|Review & editing	Writing	Wrote the paper	-	YES
6143494	30229415	JC	CRediT	Conceptualization|Literature review|Data curation|Writing|Funding|Validation|Review & editing	Funding	-	Funding acquisition	YES
6143494	30229415	JC	CRediT	Conceptualization|Literature review|Data curation|Writing|Funding|Validation|Review & editing	Validation	Performed the experiments	Validation	YES
6143494	30229415	JC	CRediT	Conceptualization|Literature review|Data curation|Writing|Funding|Validation|Review & editing	Review & editing	Wrote the paper	Writing - Review & Editing	YES
6143494	30229415	JEP	CRediT	Validation|Review & editing	Validation	Performed the experiments	Validation	YES
6143494	30229415	JEP	CRediT	Validation|Review & editing	Review & editing	Wrote the paper	Writing - Review & Editing	YES
4933823	27349312	CC	2	data collection and assembly	data collection and assembly	Performed the experiments	Investigation	YES
4933823	27349312	DF	2	data collection and assembly|manuscript writing	data collection and assembly	Performed the experiments	Investigation	YES
4933823	27349312	DF	2	data collection and assembly|manuscript writing	manuscript writing	Wrote the paper	Writing - Original Draft	YES
4933823	27349312	GC	2	conception and design|data collection and assembly|statistical analysis|manuscript writing	conception and design	Conceived and designed the experiments	Conceptualization	YES
4933823	27349312	GC	2	conception and design|data collection and assembly|statistical analysis|manuscript writing	data collection and assembly	Performed the experiments	Investigation	YES
4933823	27349312	GC	2	conception and design|data collection and assembly|statistical analysis|manuscript writing	statistical analysis	Analyzed the data	Formal analysis	YES
4933823	27349312	GC	2	conception and design|data collection and assembly|statistical analysis|manuscript writing	manuscript writing	Wrote the paper	Writing - Original Draft	YES
4933823	27349312	GF	2	data collection and assembly	data collection and assembly	Performed the experiments	Investigation	YES
4933823	27349312	GLN	2	conception and design|data collection and assembly|manuscript writing	conception and design	Conceived and designed the experiments	Conceptualization	YES
4933823	27349312	GLN	2	conception and design|data collection and assembly|manuscript writing	data collection and assembly	Performed the experiments	Investigation	YES
4933823	27349312	GLN	2	conception and design|data collection and assembly|manuscript writing	manuscript writing	Wrote the paper	Writing - Original Draft	YES
4933823	27349312	GS	2	data collection and assembly	data collection and assembly	Performed the experiments	Investigation	YES
4933823	27349312	MG	2	conception and design|data collection and assembly|manuscript writing	conception and design	Conceived and designed the experiments	Conceptualization	YES
4933823	27349312	MG	2	conception and design|data collection and assembly|manuscript writing	data collection and assembly	Performed the experiments	Investigation	YES
4933823	27349312	MG	2	conception and design|data collection and assembly|manuscript writing	manuscript writing	Wrote the paper	Writing - Original Draft	YES
4933823	27349312	PR	2	statistical analysis	statistical analysis	Analyzed the data	Formal analysis	YES
4933823	27349312	RL	2	data collection and assembly	data collection and assembly	Performed the experiments	Investigation	YES
4933823	27349312	SL	2	data collection and assembly	data collection and assembly	Performed the experiments	Investigation	YES
2040507	17971865	AB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
2040507	17971865	AB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
2040507	17971865	AB	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2040507	17971865	AL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2040507	17971865	AL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2040507	17971865	AL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2040507	17971865	AL	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2040507	17971865	CP	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2040507	17971865	DB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2040507	17971865	DB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2040507	17971865	DB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2040507	17971865	DB	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2040507	17971865	FB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
2040507	17971865	FB	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2040507	17971865	MP	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2040507	17971865	YA	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6270924	25329870	De Feo	2	supervised the project, interpreted experimental data and prepared the mauscript	supervised the project, interpreted experimental data and prepared the mauscript	Analyzed the data	Formal analysis|Supervision	YES
6146115	30232563	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6146115	30232563	HX	2	participated in the experiments	participated in the experiments	Performed the experiments	Investigation	YES
6146115	30232563	LD	2	performed out the whole study and participated in its design	performed out the whole study and participated in its design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6146115	30232563	LY	2	performed out the whole study and participated in its design	performed out the whole study and participated in its design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6146115	30232563	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
6146115	30232563	WD	2	performed out the whole study and participated in its design	performed out the whole study and participated in its design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6146115	30232563	WM	2	designed the experiments and wrote the manuscript|was responsible for initiation and supervision of the study	designed the experiments and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
6146115	30232563	WM	2	designed the experiments and wrote the manuscript|was responsible for initiation and supervision of the study	was responsible for initiation and supervision of the study	-	Supervision	YES
6146115	30232563	ZQ	2	participated in the experiments	participated in the experiments	Performed the experiments	Investigation	YES
6146115	30232563	ZY	2	designed the experiments and wrote the manuscript	designed the experiments and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5842524	29514634	AC	2	participated to the set-up of the experimental design, and to sample collection|interpreted the data	participated to the set-up of the experimental design, and to sample collection	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5842524	29514634	AC	2	participated to the set-up of the experimental design, and to sample collection|interpreted the data	interpreted the data	Analyzed the data	Formal analysis	YES
5842524	29514634	All authors	2	helped to draft the manuscript and read and approved the final version	helped to draft the manuscript and read and approved the final version	Wrote the paper	Writing - Original Draft	YES
5842524	29514634	CB	2	participated to the set-up of the experimental design, and to sample collection	participated to the set-up of the experimental design, and to sample collection	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5842524	29514634	CD	2	participated to the set-up of the experimental design, and to sample collection|generated fluidigm data and carried out analysis|interpreted the data|drafted the manuscript	participated to the set-up of the experimental design, and to sample collection	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5842524	29514634	CD	2	participated to the set-up of the experimental design, and to sample collection|generated fluidigm data and carried out analysis|interpreted the data|drafted the manuscript	generated fluidigm data and carried out analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5842524	29514634	CD	2	participated to the set-up of the experimental design, and to sample collection|generated fluidigm data and carried out analysis|interpreted the data|drafted the manuscript	interpreted the data	Analyzed the data	Formal analysis	YES
5842524	29514634	CD	2	participated to the set-up of the experimental design, and to sample collection|generated fluidigm data and carried out analysis|interpreted the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5842524	29514634	EB	2	participated to the set-up of the experimental design, and to sample collection|interpreted the data	participated to the set-up of the experimental design, and to sample collection	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5842524	29514634	EB	2	participated to the set-up of the experimental design, and to sample collection|interpreted the data	interpreted the data	Analyzed the data	Formal analysis	YES
5842524	29514634	EL	2	participated to the set-up of the experimental design, and to sample collection	participated to the set-up of the experimental design, and to sample collection	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5842524	29514634	FASN	2	enzymatic activity	enzymatic activity	-	-	NO
5842524	29514634	FG	2	participated to the set-up of the experimental design, and to sample collection|interpreted the data	participated to the set-up of the experimental design, and to sample collection	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5842524	29514634	FG	2	participated to the set-up of the experimental design, and to sample collection|interpreted the data	interpreted the data	Analyzed the data	Formal analysis	YES
5842524	29514634	JM	2	generated fluidigm data and carried out analysis	generated fluidigm data and carried out analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5842524	29514634	MB	2	generated fluidigm data and carried out analysis	generated fluidigm data and carried out analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5842524	29514634	MD	2	participated to the set-up of the experimental design, and to sample collection|interpreted the data	participated to the set-up of the experimental design, and to sample collection	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5842524	29514634	MD	2	participated to the set-up of the experimental design, and to sample collection|interpreted the data	interpreted the data	Analyzed the data	Formal analysis	YES
5842524	29514634	PFR	2	participated to the set-up of the experimental design, and to sample collection	participated to the set-up of the experimental design, and to sample collection	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5842524	29514634	SA	2	participated to the set-up of the experimental design, and to sample collection	participated to the set-up of the experimental design, and to sample collection	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5842524	29514634	SL	2	participated to the set-up of the experimental design, and to sample collection|interpreted the data|coordinated the study|drafted the manuscript	participated to the set-up of the experimental design, and to sample collection	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5842524	29514634	SL	2	participated to the set-up of the experimental design, and to sample collection|interpreted the data|coordinated the study|drafted the manuscript	interpreted the data	Analyzed the data	Formal analysis	YES
5842524	29514634	SL	2	participated to the set-up of the experimental design, and to sample collection|interpreted the data|coordinated the study|drafted the manuscript	coordinated the study	-	Project administration	YES
5842524	29514634	SL	2	participated to the set-up of the experimental design, and to sample collection|interpreted the data|coordinated the study|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5842524	29514634	SMC	2	participated to the set-up of the experimental design, and to sample collection	participated to the set-up of the experimental design, and to sample collection	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5819168	29484188	AL	2	also checked the english grammar	also checked the english grammar	-	-	NO
5819168	29484188	KL	2	conducted the study design	conducted the study design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5819168	29484188	KT	2	advised the statistical methods	advised the statistical methods	Performed the experiments|Analyzed the data	Formal analysis	YES
5819168	29484188	MN	2	helped in the data collection and the statistical analysis	helped in the data collection and the statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5819168	29484188	TO	2	conducted the study design	conducted the study design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
4418830	25938807	AN	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418830	25938807	AN	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418830	25938807	AN	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418830	25938807	AN	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418830	25938807	MK	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4418830	25938807	MK	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418830	25938807	MT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418830	25938807	MT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418830	25938807	MT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418830	25938807	MT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418830	25938807	MT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418830	25938807	SK	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4418830	25938807	SK	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418830	25938807	YK	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4418830	25938807	YK	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418830	25938807	YT	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418830	25938807	YT	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418830	25938807	YT	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418830	25938807	YT	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5852069	29568301	CW	2	designed the study|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5852069	29568301	CW	2	designed the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5852069	29568301	DH	2	provided help in experimental methods	provided help in experimental methods	Performed the experiments	Investigation	YES
5852069	29568301	DS	2	provided help in experimental methods	provided help in experimental methods	Performed the experiments	Investigation	YES
5852069	29568301	HC	2	participated in the discussion	participated in the discussion	-	-	NO
5852069	29568301	HL	2	performed the experiments and data analysis	performed the experiments and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5852069	29568301	LW	2	performed the experiments and data analysis	performed the experiments and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5852069	29568301	NZ	2	participated in the discussion	participated in the discussion	-	-	NO
5852069	29568301	QC	2	participated in the discussion	participated in the discussion	-	-	NO
5852069	29568301	ST	2	trained the use of experimental equipment	trained the use of experimental equipment	-	-	NO
5852069	29568301	SZ	2	participated in the discussion	participated in the discussion	-	-	NO
5852069	29568301	XW	2	designed the study|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5852069	29568301	XW	2	designed the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5852069	29568301	YW	2	performed the experiments and data analysis	performed the experiments and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5852069	29568301	ZZ	2	trained the use of experimental equipment	trained the use of experimental equipment	-	-	NO
2040508	17971877	AC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Suggested idea for the study	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2040508	17971877	AC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Suggested idea for the study	Analyzed the data	Analyzed the data	Formal analysis	YES
2040508	17971877	AC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Suggested idea for the study	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2040508	17971877	AC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Suggested idea for the study	Suggested idea for the study	Conceived and designed the experiments	Conceptualization	YES
2040508	17971877	ED	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2040508	17971877	ED	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2040508	17971877	ED	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2040508	17971877	ED	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2040508	17971877	ED	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2040508	17971877	ER	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
2040508	17971877	HS	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2040508	17971877	RB	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2040508	17971877	RB	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
2040508	17971877	RB	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2040508	17971877	XW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2040508	17971877	XW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
2040508	17971877	XW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4933824	27349313	AD	2	statistical and image analysis	statistical and image analysis	Analyzed the data	Formal analysis|Visualization	YES
4933824	27349313	AGK	2	histopathological analysis	histopathological analysis	Performed the experiments	Investigation	YES
4933824	27349313	BA	2	participation in study design, statistical analysis	participation in study design, statistical analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
4933824	27349313	IHC	2	evaluation, manuscript drafting	evaluation, manuscript drafting	Wrote the paper	Writing - Original Draft	YES
4933824	27349313	KS	2	statistical and image analysis	statistical and image analysis	Analyzed the data	Formal analysis|Visualization	YES
4933824	27349313	MHo	2	histopathological analysis	histopathological analysis	Performed the experiments	Investigation	YES
4933824	27349313	MHu	2	participation in study design, statistical analysis	participation in study design, statistical analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
4933824	27349313	ZG	2	participation in study design, statistical analysis	participation in study design, statistical analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5882979	29581394	All authors	2	participated in the review and contributed to this manuscript	participated in the review and contributed to this manuscript	Wrote the paper	Writing - Review & Editing	YES
4418831	25938675	DP	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418831	25938675	DP	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418831	25938675	MN	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418831	25938675	MN	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418831	25938675	MN	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418831	25938675	SA	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418831	25938675	SA	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418831	25938675	SG	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418831	25938675	SR	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418831	25938675	SV	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418831	25938675	SV	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418831	25938675	TN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418831	25938675	TN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418831	25938675	TN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418831	25938675	TN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418831	25938675	TT	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418831	25938675	TT	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418831	25938675	TT	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418831	25938675	WL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418831	25938675	WL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418831	25938675	WL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418831	25938675	WL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5827994	29497534	AB	2	are responsible for the data acquisition	are responsible for the data acquisition	Performed the experiments	Investigation	YES
5827994	29497534	AK	2	is responsible for the data acquisition and analysis	is responsible for the data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5827994	29497534	AS	2	are responsible for the data acquisition	are responsible for the data acquisition	Performed the experiments	Investigation	YES
5827994	29497534	GB	2	is responsible for the data analysis	is responsible for the data analysis	Analyzed the data	Formal analysis	YES
5827994	29497534	HAH	2	is accountable for all the aspects of the work and for ensuring that the questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	is accountable for all the aspects of the work and for ensuring that the questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved	-	-	NO
5827994	29497534	SP	2	prepared the manuscript and analyzed the data	prepared the manuscript and analyzed the data	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5845150	29523084	All authors	PLoS52	reviewed and approved the manuscript for publication	reviewed and approved the manuscript for publication	Wrote the paper	Writing - Review & Editing	YES
5845150	29523084	HH	PLoS52	conceived the idea and designed the study|analyzed the data|revised the manuscript	conceived the idea and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5845150	29523084	HH	PLoS52	conceived the idea and designed the study|analyzed the data|revised the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5845150	29523084	HH	PLoS52	conceived the idea and designed the study|analyzed the data|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5845150	29523084	JL	PLoS52	conceived the idea and designed the study|conducted the experiments|performed the bioinformatic and statistical analysis|analyzed the data|revised the manuscript	conceived the idea and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5845150	29523084	JL	PLoS52	conceived the idea and designed the study|conducted the experiments|performed the bioinformatic and statistical analysis|analyzed the data|revised the manuscript	conducted the experiments	Performed the experiments	Investigation	YES
5845150	29523084	JL	PLoS52	conceived the idea and designed the study|conducted the experiments|performed the bioinformatic and statistical analysis|analyzed the data|revised the manuscript	performed the bioinformatic and statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5845150	29523084	JL	PLoS52	conceived the idea and designed the study|conducted the experiments|performed the bioinformatic and statistical analysis|analyzed the data|revised the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5845150	29523084	JL	PLoS52	conceived the idea and designed the study|conducted the experiments|performed the bioinformatic and statistical analysis|analyzed the data|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5845150	29523084	JS	PLoS52	conceived the idea and designed the study|analyzed the data|revised the manuscript	conceived the idea and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5845150	29523084	JS	PLoS52	conceived the idea and designed the study|analyzed the data|revised the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
5845150	29523084	JS	PLoS52	conceived the idea and designed the study|analyzed the data|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5845150	29523084	LJ	PLoS52	performed the bioinformatic and statistical analysis	performed the bioinformatic and statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5845150	29523084	MK	PLoS52	conceived the idea and designed the study|analyzed the data	conceived the idea and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5845150	29523084	MK	PLoS52	conceived the idea and designed the study|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5845150	29523084	SY	PLoS52	conducted the experiments	conducted the experiments	Performed the experiments	Investigation	YES
5845150	29523084	XW	PLoS52	performed the bioinformatic and statistical analysis	performed the bioinformatic and statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5845150	29523084	YX	PLoS52	conducted the experiments	conducted the experiments	Performed the experiments	Investigation	YES
5845150	29523084	ZD	PLoS52	conceived the idea and designed the study|analyzed the data	conceived the idea and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5845150	29523084	ZD	PLoS52	conceived the idea and designed the study|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5845150	29523084	ZF	PLoS52	performed the bioinformatic and statistical analysis	performed the bioinformatic and statistical analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5845150	29523084	all authors	PLoS52	participated in the manuscript writing	participated in the manuscript writing	Wrote the paper	Writing - Original Draft	YES
4673348	26688813	Aini Ideris	2	helped in review and approval of the final paper	helped in review and approval of the final paper	Wrote the paper	Writing - Review & Editing	YES
4673348	26688813	Hadiza Altine Adamu	2	participated in conduct of research and experimentation	participated in conduct of research and experimentation	Performed the experiments	Investigation	YES
4673348	26688813	Maizaton Atmadini Abdullah	2	helped in review and approval of the final paper	helped in review and approval of the final paper	Wrote the paper	Writing - Review & Editing	YES
4673348	26688813	Maznah Ismail	2	participated in conception of idea and research design|helped in review and approval of the final paper	participated in conception of idea and research design	Conceived and designed the experiments	Conceptualization	YES
4673348	26688813	Maznah Ismail	2	participated in conception of idea and research design|helped in review and approval of the final paper	helped in review and approval of the final paper	Wrote the paper	Writing - Review & Editing	YES
4673348	26688813	Mustapha Umar Imam	2	participated in conduct of research and experimentation|participated in data analyses|helped in drafting of the paper|helped in review and approval of the final paper	participated in conduct of research and experimentation	Performed the experiments	Investigation	YES
4673348	26688813	Mustapha Umar Imam	2	participated in conduct of research and experimentation|participated in data analyses|helped in drafting of the paper|helped in review and approval of the final paper	participated in data analyses	Analyzed the data	Formal analysis	YES
4673348	26688813	Mustapha Umar Imam	2	participated in conduct of research and experimentation|participated in data analyses|helped in drafting of the paper|helped in review and approval of the final paper	helped in drafting of the paper	Wrote the paper	Writing - Original Draft	YES
4673348	26688813	Mustapha Umar Imam	2	participated in conduct of research and experimentation|participated in data analyses|helped in drafting of the paper|helped in review and approval of the final paper	helped in review and approval of the final paper	Wrote the paper	Writing - Review & Editing	YES
4673348	26688813	Norsharina Ismail	2	participated in conduct of research and experimentation	participated in conduct of research and experimentation	Performed the experiments	Investigation	YES
4673348	26688813	Nur Diyana Md	2	participated in conduct of research and experimentation	participated in conduct of research and experimentation	Performed the experiments	Investigation	YES
4673348	26688813	Nur Hanisah Azmi	2	participated in conduct of research and experimentation	participated in conduct of research and experimentation	Performed the experiments	Investigation	YES
4673348	26688813	Waiteng Wong	2	participated in conduct of research and experimentation	participated in conduct of research and experimentation	Performed the experiments	Investigation	YES
4673348	26688813	Zhang Yida	2	participated in conception of idea and research design|participated in conduct of research and experimentation|participated in data analyses|helped in drafting of the paper	participated in conception of idea and research design	Conceived and designed the experiments	Conceptualization	YES
4673348	26688813	Zhang Yida	2	participated in conception of idea and research design|participated in conduct of research and experimentation|participated in data analyses|helped in drafting of the paper	participated in conduct of research and experimentation	Performed the experiments	Investigation	YES
4673348	26688813	Zhang Yida	2	participated in conception of idea and research design|participated in conduct of research and experimentation|participated in data analyses|helped in drafting of the paper	participated in data analyses	Analyzed the data	Formal analysis	YES
4673348	26688813	Zhang Yida	2	participated in conception of idea and research design|participated in conduct of research and experimentation|participated in data analyses|helped in drafting of the paper	helped in drafting of the paper	Wrote the paper	Writing - Original Draft	YES
4933825	27349314	EW	2	experiments concept and design, paper writing|experiments performing|data analysis	experiments concept and design, paper writing	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology	YES
4933825	27349314	EW	2	experiments concept and design, paper writing|experiments performing|data analysis	experiments performing	Performed the experiments	Investigation	YES
4933825	27349314	EW	2	experiments concept and design, paper writing|experiments performing|data analysis	data analysis	Analyzed the data	Formal analysis	YES
4933825	27349314	KK	2	experiments performing	experiments performing	Performed the experiments	Investigation	YES
4933825	27349314	KM	2	experiments performing|data analysis	experiments performing	Performed the experiments	Investigation	YES
4933825	27349314	KM	2	experiments performing|data analysis	data analysis	Analyzed the data	Formal analysis	YES
4933825	27349314	MO	2	experiments performing|data analysis	experiments performing	Performed the experiments	Investigation	YES
4933825	27349314	MO	2	experiments performing|data analysis	data analysis	Analyzed the data	Formal analysis	YES
4933825	27349314	PK	2	experiments performing|data analysis	experiments performing	Performed the experiments	Investigation	YES
4933825	27349314	PK	2	experiments performing|data analysis	data analysis	Analyzed the data	Formal analysis	YES
6146970	30238175	AIO	PLoS52	performed the experiment and drafted the manuscript|analyzed the data|provided materials and reagents for the molecular analysis	performed the experiment and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6146970	30238175	AIO	PLoS52	performed the experiment and drafted the manuscript|analyzed the data|provided materials and reagents for the molecular analysis	analyzed the data	Analyzed the data	Formal analysis	YES
6146970	30238175	AIO	PLoS52	performed the experiment and drafted the manuscript|analyzed the data|provided materials and reagents for the molecular analysis	provided materials and reagents for the molecular analysis	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
6146970	30238175	AO	PLoS52	supervised the study	supervised the study	-	Supervision	YES
6146970	30238175	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6146970	30238175	MA	PLoS52	designed the experiment and provided mushroom samples|performed the experiment and drafted the manuscript|provided materials and reagents for the molecular analysis	designed the experiment and provided mushroom samples	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Methodology|Resources	YES
6146970	30238175	MA	PLoS52	designed the experiment and provided mushroom samples|performed the experiment and drafted the manuscript|provided materials and reagents for the molecular analysis	performed the experiment and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6146970	30238175	MA	PLoS52	designed the experiment and provided mushroom samples|performed the experiment and drafted the manuscript|provided materials and reagents for the molecular analysis	provided materials and reagents for the molecular analysis	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
6146970	30238175	MN	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
6146970	30238175	OO	PLoS52	designed the experiment and provided mushroom samples|supervised the study	designed the experiment and provided mushroom samples	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Methodology|Resources	YES
6146970	30238175	OO	PLoS52	designed the experiment and provided mushroom samples|supervised the study	supervised the study	-	Supervision	YES
6146970	30238175	YT	PLoS52	performed the experiment and drafted the manuscript|analyzed the data|provided materials and reagents for the molecular analysis	performed the experiment and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6146970	30238175	YT	PLoS52	performed the experiment and drafted the manuscript|analyzed the data|provided materials and reagents for the molecular analysis	analyzed the data	Analyzed the data	Formal analysis	YES
6146970	30238175	YT	PLoS52	performed the experiment and drafted the manuscript|analyzed the data|provided materials and reagents for the molecular analysis	provided materials and reagents for the molecular analysis	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
3840484	24096875	EM	2	designed the experiment, conducted experiment	designed the experiment, conducted experiment	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3840484	24096875	EMBO	2	molecular medicine online	molecular medicine online	Performed the experiments	Investigation	YES
3840484	24096875	MK	2	designed and performed in vivo heart experiments	designed and performed in vivo heart experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3840484	24096875	PK	2	designed the study, performed data analysis and interpretation, prepared the manuscript	designed the study, performed data analysis and interpretation, prepared the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3840484	24096875	RG	2	designed the experiment, conducted experiment, wrote the manuscript	designed the experiment, conducted experiment, wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
3840484	24096875	UP	2	designed the experiment	designed the experiment	Conceived and designed the experiments	Methodology	YES
5852072	29568307	GB	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5852072	29568307	JW	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5852072	29568307	KL	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5852072	29568307	QZ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5852072	29568307	SS	PLoS52	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5852072	29568307	WH	PLoS52	performed the experiments|drafted the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5852072	29568307	WH	PLoS52	performed the experiments|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5852072	29568307	WZ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5852072	29568307	ZF	PLoS52	designed the research|performed the experiments|drafted the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
5852072	29568307	ZF	PLoS52	designed the research|performed the experiments|drafted the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5852072	29568307	ZF	PLoS52	designed the research|performed the experiments|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
2040509	17987113	CM	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2040509	17987113	HC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2040509	17987113	HC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2040509	17987113	HC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2040509	17987113	HK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
2040509	17987113	SA	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
2040509	17987113	SA	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2040509	17987113	SK	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2040509	17987113	SK	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2040509	17987113	SR	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
2040509	17987113	VS	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2040509	17987113	VS	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2040509	17987113	YK	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2040509	17987113	YK	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2040509	17987113	ZT	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5882983	29581398	Both authors	2	contributed to model development and the written presentation	contributed to model development and the written presentation	Performed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
4418832	25938768	AKS	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418832	25938768	AKS	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418832	25938768	EC	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418832	25938768	GU	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418832	25938768	ISS	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418832	25938768	LV	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418832	25938768	LV	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418832	25938768	MED	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418832	25938768	MED	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418832	25938768	MED	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418832	25938768	MED	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418832	25938768	MSM	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418832	25938768	MSM	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418832	25938768	SH	PLoS5	Conceived and designed the experiments|Designed the nbscp questionnaire	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418832	25938768	SH	PLoS5	Conceived and designed the experiments|Designed the nbscp questionnaire	Designed the nbscp questionnaire	Conceived and designed the experiments	-	YES
4418832	25938768	SQ	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418832	25938768	TG	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6270926	25387352	All of the authors	2	participated in the revision and corrections of the manuscript	participated in the revision and corrections of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5828304	29497535	HY	2	made substantial contributions in data acquisition and writing of the manuscript|contributed to the study design, statistical analysis, interpretation of data, and final approval of the manuscript|critically revised the manuscript for important intellectual content	made substantial contributions in data acquisition and writing of the manuscript	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Resources|Writing - Original Draft	YES
5828304	29497535	HY	2	made substantial contributions in data acquisition and writing of the manuscript|contributed to the study design, statistical analysis, interpretation of data, and final approval of the manuscript|critically revised the manuscript for important intellectual content	contributed to the study design, statistical analysis, interpretation of data, and final approval of the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Methodology|Resources	YES
5828304	29497535	HY	2	made substantial contributions in data acquisition and writing of the manuscript|contributed to the study design, statistical analysis, interpretation of data, and final approval of the manuscript|critically revised the manuscript for important intellectual content	critically revised the manuscript for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5828304	29497535	KM	2	made equally substantial contributions in data acquisition and reviewing the manuscript	made equally substantial contributions in data acquisition and reviewing the manuscript	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Resources|Writing - Review & Editing	YES
5828304	29497535	TM	2	contributed to the study design, statistical analysis, interpretation of data, and final approval of the manuscript|supervised the study	contributed to the study design, statistical analysis, interpretation of data, and final approval of the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Methodology|Resources	YES
5828304	29497535	TM	2	contributed to the study design, statistical analysis, interpretation of data, and final approval of the manuscript|supervised the study	supervised the study	-	Supervision	YES
5828304	29497535	TY	2	made equally substantial contributions in data acquisition and reviewing the manuscript	made equally substantial contributions in data acquisition and reviewing the manuscript	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Resources|Writing - Review & Editing	YES
5828304	29497535	YK	2	made equally substantial contributions in data acquisition and reviewing the manuscript	made equally substantial contributions in data acquisition and reviewing the manuscript	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Investigation|Resources|Writing - Review & Editing	YES
5828304	29497535	YO	2	contributed to the study design, statistical analysis, interpretation of data, and final approval of the manuscript	contributed to the study design, statistical analysis, interpretation of data, and final approval of the manuscript	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Methodology|Resources	YES
4674578	26693485	All authors	2	approved the final version	approved the final version	-	-	NO
4674578	26693485	Germaine Hanquet	2	designed the study, performed the literature review, and developed the guidance|contributed equally to this paper	designed the study, performed the literature review, and developed the guidance	Conceived and designed the experiments|Performed the experiments	Formal analysis|Investigation|Methodology|Supervision	YES
4674578	26693485	Germaine Hanquet	2	designed the study, performed the literature review, and developed the guidance|contributed equally to this paper	contributed equally to this paper	-	-	NO
4674578	26693485	James M. Stuart	2	designed the study, performed the literature review, and developed the guidance	designed the study, performed the literature review, and developed the guidance	Conceived and designed the experiments|Performed the experiments	Formal analysis|Investigation|Methodology|Supervision	YES
4674578	26693485	Pawel Stefanoff	2	designed the study, performed the literature review, and developed the guidance|contributed equally to this paper	designed the study, performed the literature review, and developed the guidance	Conceived and designed the experiments|Performed the experiments	Formal analysis|Investigation|Methodology|Supervision	YES
4674578	26693485	Pawel Stefanoff	2	designed the study, performed the literature review, and developed the guidance|contributed equally to this paper	contributed equally to this paper	-	-	NO
4674578	26693485	Sigrid Heuberger	2	designed the study, performed the literature review, and developed the guidance	designed the study, performed the literature review, and developed the guidance	Conceived and designed the experiments|Performed the experiments	Formal analysis|Investigation|Methodology|Supervision	YES
4674578	26693485	Wiebke Hellenbrand	2	designed the study, performed the literature review, and developed the guidance	designed the study, performed the literature review, and developed the guidance	Conceived and designed the experiments|Performed the experiments	Formal analysis|Investigation|Methodology|Supervision	YES
4418833	25938681	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418833	25938681	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418833	25938681	AK	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418833	25938681	ANA	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418833	25938681	ANA	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418833	25938681	ANA	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418833	25938681	GN	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418833	25938681	GN	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418833	25938681	GN	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418833	25938681	IO	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418833	25938681	IO	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418833	25938681	IO	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418833	25938681	JKT	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418833	25938681	JKT	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418833	25938681	JKT	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418833	25938681	LTF	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418833	25938681	LTF	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418833	25938681	LTF	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418833	25938681	NB	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418833	25938681	NB	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418833	25938681	NB	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418833	25938681	SAL	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418833	25938681	TT	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418833	25938681	TT	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418833	25938681	VN	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418833	25938681	VN	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418833	25938681	VN	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5845213	29523080	GM	2	conceived of the study, prepared the genomic library, conducted sequence analysis and comparisons, and drafted the manuscript as well as its tables and figs	conceived of the study, prepared the genomic library, conducted sequence analysis and comparisons, and drafted the manuscript as well as its tables and figs	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Visualization|Writing - Original Draft	YES
5845213	29523080	NCBI	2	contributed to manuscript preparation	contributed to manuscript preparation	Wrote the paper	Writing - Original Draft	YES
5845213	29523080	SB	2	performed genomic sequencing, and contributed to manuscript preparation	performed genomic sequencing, and contributed to manuscript preparation	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6150865	30242564	All	PLoS52	data generated or analyzed during this study are included in the figures and tables	data generated or analyzed during this study are included in the figures and tables	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
6150865	30242564	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6150865	30242564	HH	PLoS52	designed the experiments|supervised the research	designed the experiments	Conceived and designed the experiments	Methodology	YES
6150865	30242564	HH	PLoS52	designed the experiments|supervised the research	supervised the research	-	Supervision	YES
6150865	30242564	Ivan Hajnal	PLoS52	for critical reading and editing of our manuscript	for critical reading and editing of our manuscript	Wrote the paper	Writing - Review & Editing	YES
6150865	30242564	LJR	PLoS52	designed the experiments|analyzed the data	designed the experiments	Conceived and designed the experiments	Methodology	YES
6150865	30242564	LJR	PLoS52	designed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
6150865	30242564	The authors	PLoS52	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
6150865	30242564	XJJ	PLoS52	performed the research|polished the paper	performed the research	Performed the experiments	Investigation	YES
6150865	30242564	XJJ	PLoS52	performed the research|polished the paper	polished the paper	Wrote the paper	Writing - Review & Editing	YES
6150865	30242564	XMS	PLoS52	performed the research|analyzed the data|wrote the paper	performed the research	Performed the experiments	Investigation	YES
6150865	30242564	XMS	PLoS52	performed the research|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
6150865	30242564	XMS	PLoS52	performed the research|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5852109	29568308	Both authors	2	have accepted the final version of the manuscript and agreed to be accountable for all aspects of the work	have accepted the final version of the manuscript and agreed to be accountable for all aspects of the work	-	-	NO
5852109	29568308	The authors	2	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	Performed the experiments	Investigation	YES
3840485	24106222	AA	2	designed and performed experiments, analysed data and wrote the paper	designed and performed experiments, analysed data and wrote the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
3840485	24106222	AC	2	designed and performed experiments, analysed data and wrote the paper	designed and performed experiments, analysed data and wrote the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
3840485	24106222	ADA	2	coordinated coagulation assays	coordinated coagulation assays	Performed the experiments	Investigation|Project administration	YES
3840485	24106222	FR	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
3840485	24106222	KG	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
3840485	24106222	LN	2	coordinated the work and wrote the paper	coordinated the work and wrote the paper	Wrote the paper	Project administration|Writing - Original Draft	YES
3840485	24106222	MA	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
3840485	24106222	MGR	2	coordinated the work and wrote the paper	coordinated the work and wrote the paper	Wrote the paper	Project administration|Writing - Original Draft	YES
3840485	24106222	PDV	2	performed coagulation assays and analysed data	performed coagulation assays and analysed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3840485	24106222	SB	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
6270927	24756129	Bo Wei	PLoS52	designed the research|performed the experiments|analyzed the data|wrote the paper	designed the research	Conceived and designed the experiments	Methodology	YES
6270927	24756129	Bo Wei	PLoS52	designed the research|performed the experiments|analyzed the data|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
6270927	24756129	Bo Wei	PLoS52	designed the research|performed the experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
6270927	24756129	Bo Wei	PLoS52	designed the research|performed the experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270927	24756129	Cairui Wang	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
6270927	24756129	Dan Sun	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
6270927	24756129	Fangrui Ding	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
6270927	24756129	Feng Xie	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
6270927	24756129	Jichun Yang	PLoS52	designed the research|wrote the paper	designed the research	Conceived and designed the experiments	Methodology	YES
6270927	24756129	Jichun Yang	PLoS52	designed the research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270927	24756129	Jie Liu	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
6270927	24756129	Linhong Cai	PLoS52	analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
6270927	24756129	Linhong Cai	PLoS52	analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270927	24756129	Ming Su	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270927	24756129	Xiaoyu Chai	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
6270927	24756129	Xinmin Liu	PLoS52	designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
6270927	24756129	Yanhua Wang	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
6270927	24756129	Youfei Guan	PLoS52	designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
4933826	27349315	CG	2	critical revision of the manuscript	critical revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4933826	27349315	DF	2	research conception and design|interpretation of experiments results|manuscript drafting	research conception and design	Conceived and designed the experiments	Conceptualization	YES
4933826	27349315	DF	2	research conception and design|interpretation of experiments results|manuscript drafting	interpretation of experiments results	Analyzed the data	Formal analysis	YES
4933826	27349315	DF	2	research conception and design|interpretation of experiments results|manuscript drafting	manuscript drafting	Wrote the paper	Writing - Original Draft	YES
4933826	27349315	FL	2	experiments performing|interpretation of experiments results	experiments performing	Performed the experiments	Investigation	YES
4933826	27349315	FL	2	experiments performing|interpretation of experiments results	interpretation of experiments results	Analyzed the data	Formal analysis	YES
4933826	27349315	GF	2	research conception and design|critical revision of the manuscript	research conception and design	Conceived and designed the experiments	Conceptualization	YES
4933826	27349315	GF	2	research conception and design|critical revision of the manuscript	critical revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
4933826	27349315	MM	2	research conception and design|manuscript drafting	research conception and design	Conceived and designed the experiments	Conceptualization	YES
4933826	27349315	MM	2	research conception and design|manuscript drafting	manuscript drafting	Wrote the paper	Writing - Original Draft	YES
4933826	27349315	RA	2	critical revision of the manuscript	critical revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5831732	29507729	TF	2	performed the literature review and wrote the draft	performed the literature review and wrote the draft	Performed the experiments|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
2040510	17971868	AS	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2040510	17971868	AS	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2040510	17971868	DB	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
2040510	17971868	DB	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2040510	17971868	EN	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
2040510	17971868	EN	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2040510	17971868	FM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
2040510	17971868	FM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2040510	17971868	MG	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
2040510	17971868	MG	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2040510	17971868	PB	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
2040510	17971868	PB	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2040510	17971868	PF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2040510	17971868	PF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2040510	17971868	PF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2040510	17971868	PF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2040510	17971868	PF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2040510	17971868	PF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2040510	17971868	PM	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
2040510	17971868	PM	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4674579	26693482	The authors	2	agree that all of them contributed equally to the presented work and therefore all shall be regarded as the leading authors	agree that all of them contributed equally to the presented work and therefore all shall be regarded as the leading authors	-	-	NO
4418834	25938551	AJQ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418834	25938551	AJQ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418834	25938551	AJQ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418834	25938551	HTZ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4418834	25938551	HTZ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4418834	25938551	HTZ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418834	25938551	HXS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4418834	25938551	HXS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418834	25938551	JQY	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418834	25938551	JQY	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418834	25938551	JQY	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418834	25938551	KQ	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418834	25938551	KQ	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418834	25938551	KQ	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418834	25938551	XMH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418834	25938551	XMH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418834	25938551	XMH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418834	25938551	XMH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418834	25938551	XMH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4933827	27349316	FZ	2	participation in experiments performing, data analysis, manuscript drafting|assistance to sample collection and experiments, participation in manuscript revision	participation in experiments performing, data analysis, manuscript drafting	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4933827	27349316	FZ	2	participation in experiments performing, data analysis, manuscript drafting|assistance to sample collection and experiments, participation in manuscript revision	assistance to sample collection and experiments, participation in manuscript revision	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4933827	27349316	HZ	2	participation in experiments performing, data analysis, manuscript drafting	participation in experiments performing, data analysis, manuscript drafting	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4933827	27349316	JW	2	participation in experiments performing, data analysis, manuscript drafting|assistance to sample collection and experiments, participation in manuscript revision	participation in experiments performing, data analysis, manuscript drafting	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4933827	27349316	JW	2	participation in experiments performing, data analysis, manuscript drafting|assistance to sample collection and experiments, participation in manuscript revision	assistance to sample collection and experiments, participation in manuscript revision	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4933827	27349316	LZ	2	assistance to sample collection and experiments, participation in manuscript revision	assistance to sample collection and experiments, participation in manuscript revision	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4933827	27349316	QW	2	study design and supervision, manuscript revision	study design and supervision, manuscript revision	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Review & Editing	YES
4933827	27349316	XS	2	assistance to sample collection and experiments, participation in manuscript revision	assistance to sample collection and experiments, participation in manuscript revision	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
4933827	27349316	YH	2	study design and supervision, manuscript revision	study design and supervision, manuscript revision	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Review & Editing	YES
4933827	27349316	YJ	2	participation in experiments performing, data analysis, manuscript drafting	participation in experiments performing, data analysis, manuscript drafting	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4933827	27349316	ZY	2	study design and supervision, manuscript revision	study design and supervision, manuscript revision	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Review & Editing	YES
5845326	29523071	AP	2	conceptualized the research and designed the experiments	conceptualized the research and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5845326	29523071	DM	2	performed in silico molecular interaction studies	performed in silico molecular interaction studies	Performed the experiments	Formal analysis|Investigation	YES
5845326	29523071	MD	2	conceptualized the research and designed the experiments|wrote the article with help from all the co-authors	conceptualized the research and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5845326	29523071	MD	2	conceptualized the research and designed the experiments|wrote the article with help from all the co-authors	wrote the article with help from all the co-authors	Wrote the paper	Writing - Original Draft	YES
5845326	29523071	PB	2	performed tissue collection, nucleic acids extraction and all sequence data analyses	performed tissue collection, nucleic acids extraction and all sequence data analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5845326	29523071	SC	2	carried out the real time rt-qpcr gene expression analyses	carried out the real time rt-qpcr gene expression analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5845326	29523071	SD	2	performed gene cloning, sequencing and diurnal experiments	performed gene cloning, sequencing and diurnal experiments	Performed the experiments	Investigation	YES
6150868	30242525	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
2040517	17987115	AS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2040517	17987115	AS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2040517	17987115	AS	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2040517	17987115	PZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2040517	17987115	PZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2040517	17987115	PZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2040517	17987115	PZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2040517	17987115	PZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2040517	17987115	SA	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2040517	17987115	SA	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5831844	29507728	AB	2	participated in critical revision for intellectual content	participated in critical revision for intellectual content	Wrote the paper	Writing - Review & Editing	YES
5831844	29507728	DS	2	participated in the study design and revision of the article for intellectual content	participated in the study design and revision of the article for intellectual content	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5831844	29507728	KF	2	had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis	had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis	Analyzed the data	Data curation|Formal analysis	YES
5831844	29507728	TO	2	participated in the study design, drafting of the article, analysis and interpretation of data, and revision of the article for intellectual content	participated in the study design, drafting of the article, analysis and interpretation of data, and revision of the article for intellectual content	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
3840486	24106230	BEH	2	performed experiments|designed experiments|interpreted data	performed experiments	Performed the experiments	Investigation	YES
3840486	24106230	BEH	2	performed experiments|designed experiments|interpreted data	designed experiments	Conceived and designed the experiments	Methodology	YES
3840486	24106230	BEH	2	performed experiments|designed experiments|interpreted data	interpreted data	Analyzed the data	Formal analysis	YES
3840486	24106230	DMM	2	performed experiments|designed experiments|interpreted data|wrote the manuscript	performed experiments	Performed the experiments	Investigation	YES
3840486	24106230	DMM	2	performed experiments|designed experiments|interpreted data|wrote the manuscript	designed experiments	Conceived and designed the experiments	Methodology	YES
3840486	24106230	DMM	2	performed experiments|designed experiments|interpreted data|wrote the manuscript	interpreted data	Analyzed the data	Formal analysis	YES
3840486	24106230	DMM	2	performed experiments|designed experiments|interpreted data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3840486	24106230	GQP	2	performed experiments|designed experiments|interpreted data	performed experiments	Performed the experiments	Investigation	YES
3840486	24106230	GQP	2	performed experiments|designed experiments|interpreted data	designed experiments	Conceived and designed the experiments	Methodology	YES
3840486	24106230	GQP	2	performed experiments|designed experiments|interpreted data	interpreted data	Analyzed the data	Formal analysis	YES
3840486	24106230	KAH	2	interpreted data|provided critical reagents|wrote the manuscript	interpreted data	Analyzed the data	Formal analysis	YES
3840486	24106230	KAH	2	interpreted data|provided critical reagents|wrote the manuscript	provided critical reagents	Contributed reagents/materials/analysis tools	Resources	YES
3840486	24106230	KAH	2	interpreted data|provided critical reagents|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3840486	24106230	PAL	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
3840486	24106230	RWH	2	designed experiments|interpreted data|supervised and coordinated the study|wrote the manuscript	designed experiments	Conceived and designed the experiments	Methodology	YES
3840486	24106230	RWH	2	designed experiments|interpreted data|supervised and coordinated the study|wrote the manuscript	interpreted data	Analyzed the data	Formal analysis	YES
3840486	24106230	RWH	2	designed experiments|interpreted data|supervised and coordinated the study|wrote the manuscript	supervised and coordinated the study	-	Project administration|Supervision	YES
3840486	24106230	RWH	2	designed experiments|interpreted data|supervised and coordinated the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3840486	24106230	SN	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
3840486	24106230	XW	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
6270928	24879613	PDE	2	selectivity measurements, manuscript writing, drawing and correction|selectivity measurements	selectivity measurements, manuscript writing, drawing and correction	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
6270928	24879613	PDE	2	selectivity measurements, manuscript writing, drawing and correction|selectivity measurements	selectivity measurements	Performed the experiments	Investigation	YES
5882987	29581402	All authors	2	contributed to interpreting the results and writing the manuscript	contributed to interpreting the results and writing the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5882987	29581402	J.D.Y.	2	conceived of the initial project design|designed the modelling framework and conducted the analyses	conceived of the initial project design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5882987	29581402	J.D.Y.	2	conceived of the initial project design|designed the modelling framework and conducted the analyses	designed the modelling framework and conducted the analyses	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5882987	29581402	J.P.G.	2	designed the modelling framework and conducted the analyses	designed the modelling framework and conducted the analyses	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5882987	29581402	J.W.M.	2	conceived of the initial project design	conceived of the initial project design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5882987	29581402	T.G.	2	designed the modelling framework and conducted the analyses	designed the modelling framework and conducted the analyses	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5852111	29568304	C-HH	2	cultivated the banana plantlets, extracted rna and detected enzyme activity, and participated in the bioinformatics analysis	cultivated the banana plantlets, extracted rna and detected enzyme activity, and participated in the bioinformatics analysis	Performed the experiments	Formal analysis|Investigation	YES
5852111	29568304	C-YL	2	drafted the manuscript, designed the tables, critically reviewed the manuscript, and provided the guidance	drafted the manuscript, designed the tables, critically reviewed the manuscript, and provided the guidance	Conceived and designed the experiments|Wrote the paper	Supervision|Writing - Original Draft|Writing - Review & Editing	YES
5852111	29568304	F-CB	2	cultivated the banana plantlets, extracted rna and detected enzyme activity, and participated in the bioinformatics analysis	cultivated the banana plantlets, extracted rna and detected enzyme activity, and participated in the bioinformatics analysis	Performed the experiments	Formal analysis|Investigation	YES
5852111	29568304	G-JY	2	conceived and designed the study, and wrote the manuscript	conceived and designed the study, and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
5852111	29568304	G-MD	2	cultivated the banana plantlets, extracted rna and detected enzyme activity, and participated in the bioinformatics analysis	cultivated the banana plantlets, extracted rna and detected enzyme activity, and participated in the bioinformatics analysis	Performed the experiments	Formal analysis|Investigation	YES
5852111	29568304	J-HL	2	conceived and designed the study, and wrote the manuscript	conceived and designed the study, and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
5852111	29568304	JG	2	conceived and designed the study, and wrote the manuscript	conceived and designed the study, and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
5852111	29568304	OS	2	cultivated the banana plantlets, extracted rna and detected enzyme activity, and participated in the bioinformatics analysis	cultivated the banana plantlets, extracted rna and detected enzyme activity, and participated in the bioinformatics analysis	Performed the experiments	Formal analysis|Investigation	YES
5852111	29568304	Q-SY	2	conceived and designed the study, and wrote the manuscript	conceived and designed the study, and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
5852111	29568304	SZ	2	drafted the manuscript, designed the tables, critically reviewed the manuscript, and provided the guidance	drafted the manuscript, designed the tables, critically reviewed the manuscript, and provided the guidance	Conceived and designed the experiments|Wrote the paper	Supervision|Writing - Original Draft|Writing - Review & Editing	YES
5852111	29568304	T-XD	2	cultivated the banana plantlets, extracted rna and detected enzyme activity, and participated in the bioinformatics analysis	cultivated the banana plantlets, extracted rna and detected enzyme activity, and participated in the bioinformatics analysis	Performed the experiments	Formal analysis|Investigation	YES
5852111	29568304	W-DH	2	conceived and designed the study, and wrote the manuscript	conceived and designed the study, and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
5852111	29568304	X-HS	2	cultivated the banana plantlets, extracted rna and detected enzyme activity, and participated in the bioinformatics analysis|drafted the manuscript, designed the tables, critically reviewed the manuscript, and provided the guidance	cultivated the banana plantlets, extracted rna and detected enzyme activity, and participated in the bioinformatics analysis	Performed the experiments	Formal analysis|Investigation	YES
5852111	29568304	X-HS	2	cultivated the banana plantlets, extracted rna and detected enzyme activity, and participated in the bioinformatics analysis|drafted the manuscript, designed the tables, critically reviewed the manuscript, and provided the guidance	drafted the manuscript, designed the tables, critically reviewed the manuscript, and provided the guidance	Conceived and designed the experiments|Wrote the paper	Supervision|Writing - Original Draft|Writing - Review & Editing	YES
2040518	17971850	KN	PLoS5	Conceived and designed the experiments|Wrote the paper|Designed the research program|Discussed the results|Commented on the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2040518	17971850	KN	PLoS5	Conceived and designed the experiments|Wrote the paper|Designed the research program|Discussed the results|Commented on the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2040518	17971850	KN	PLoS5	Conceived and designed the experiments|Wrote the paper|Designed the research program|Discussed the results|Commented on the manuscript	Designed the research program	Conceived and designed the experiments	Methodology	YES
2040518	17971850	KN	PLoS5	Conceived and designed the experiments|Wrote the paper|Designed the research program|Discussed the results|Commented on the manuscript	Discussed the results	-	-	NO
2040518	17971850	KN	PLoS5	Conceived and designed the experiments|Wrote the paper|Designed the research program|Discussed the results|Commented on the manuscript	Commented on the manuscript	-	-	NO
2040518	17971850	OK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the research program|Conducted field research and laboratory experiments|Discussed the results|Commented on the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2040518	17971850	OK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the research program|Conducted field research and laboratory experiments|Discussed the results|Commented on the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
2040518	17971850	OK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the research program|Conducted field research and laboratory experiments|Discussed the results|Commented on the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
2040518	17971850	OK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the research program|Conducted field research and laboratory experiments|Discussed the results|Commented on the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2040518	17971850	OK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the research program|Conducted field research and laboratory experiments|Discussed the results|Commented on the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2040518	17971850	OK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the research program|Conducted field research and laboratory experiments|Discussed the results|Commented on the manuscript	Designed the research program	Conceived and designed the experiments	Methodology	YES
2040518	17971850	OK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the research program|Conducted field research and laboratory experiments|Discussed the results|Commented on the manuscript	Conducted field research and laboratory experiments	Performed the experiments	Investigation	YES
2040518	17971850	OK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the research program|Conducted field research and laboratory experiments|Discussed the results|Commented on the manuscript	Discussed the results	-	-	NO
2040518	17971850	OK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the research program|Conducted field research and laboratory experiments|Discussed the results|Commented on the manuscript	Commented on the manuscript	-	-	NO
2040518	17971850	TI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the research program|Conducted field research and laboratory experiments|Discussed the results|Commented on the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2040518	17971850	TI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the research program|Conducted field research and laboratory experiments|Discussed the results|Commented on the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
2040518	17971850	TI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the research program|Conducted field research and laboratory experiments|Discussed the results|Commented on the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
2040518	17971850	TI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the research program|Conducted field research and laboratory experiments|Discussed the results|Commented on the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2040518	17971850	TI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the research program|Conducted field research and laboratory experiments|Discussed the results|Commented on the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2040518	17971850	TI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the research program|Conducted field research and laboratory experiments|Discussed the results|Commented on the manuscript	Designed the research program	Conceived and designed the experiments	Methodology	YES
2040518	17971850	TI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the research program|Conducted field research and laboratory experiments|Discussed the results|Commented on the manuscript	Conducted field research and laboratory experiments	Performed the experiments	Investigation	YES
2040518	17971850	TI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the research program|Conducted field research and laboratory experiments|Discussed the results|Commented on the manuscript	Discussed the results	-	-	NO
2040518	17971850	TI	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Designed the research program|Conducted field research and laboratory experiments|Discussed the results|Commented on the manuscript	Commented on the manuscript	-	-	NO
4674585	26693487	Cheng Cheng	2	contributed equally to this work	contributed equally to this work	-	-	NO
4418835	25938561	HZ	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4418835	25938561	HZ	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418835	25938561	JW	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418835	25938561	JW	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418835	25938561	KL	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418835	25938561	QXY	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418835	25938561	RM	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4418835	25938561	XS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418835	25938561	ZW	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418835	25938561	ZW	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4933828	27349317	all the authors	2	contributed equally to this work	contributed equally to this work	-	-	NO
5859397	29554878	EM	PLoS52	interpreted results of experiments|contributed reagents/materials/analysis tools|edited and revised manuscript|approved final version of manuscript	interpreted results of experiments	Analyzed the data	Formal analysis	YES
5859397	29554878	EM	PLoS52	interpreted results of experiments|contributed reagents/materials/analysis tools|edited and revised manuscript|approved final version of manuscript	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5859397	29554878	EM	PLoS52	interpreted results of experiments|contributed reagents/materials/analysis tools|edited and revised manuscript|approved final version of manuscript	edited and revised manuscript	Wrote the paper	Writing - Review & Editing	YES
5859397	29554878	EM	PLoS52	interpreted results of experiments|contributed reagents/materials/analysis tools|edited and revised manuscript|approved final version of manuscript	approved final version of manuscript	-	-	NO
5859397	29554878	FJ	PLoS52	performed experiments|analyzed data|interpreted results of experiments|drafted the manuscript|prepared figures|approved final version of manuscript	performed experiments	Performed the experiments	Investigation	YES
5859397	29554878	FJ	PLoS52	performed experiments|analyzed data|interpreted results of experiments|drafted the manuscript|prepared figures|approved final version of manuscript	analyzed data	Analyzed the data	Formal analysis	YES
5859397	29554878	FJ	PLoS52	performed experiments|analyzed data|interpreted results of experiments|drafted the manuscript|prepared figures|approved final version of manuscript	interpreted results of experiments	Analyzed the data	Formal analysis	YES
5859397	29554878	FJ	PLoS52	performed experiments|analyzed data|interpreted results of experiments|drafted the manuscript|prepared figures|approved final version of manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5859397	29554878	FJ	PLoS52	performed experiments|analyzed data|interpreted results of experiments|drafted the manuscript|prepared figures|approved final version of manuscript	prepared figures	-	Visualization	YES
5859397	29554878	FJ	PLoS52	performed experiments|analyzed data|interpreted results of experiments|drafted the manuscript|prepared figures|approved final version of manuscript	approved final version of manuscript	-	-	NO
5859397	29554878	KB	PLoS52	made the conception and design of research|performed experiments|approved final version of manuscript	made the conception and design of research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5859397	29554878	KB	PLoS52	made the conception and design of research|performed experiments|approved final version of manuscript	performed experiments	Performed the experiments	Investigation	YES
5859397	29554878	KB	PLoS52	made the conception and design of research|performed experiments|approved final version of manuscript	approved final version of manuscript	-	-	NO
5859397	29554878	KW	PLoS52	made the conception and design of research|supervised the experiment|performed experiments|analyzed data|interpreted results of experiments|edited and revised manuscript|approved final version of manuscript	made the conception and design of research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5859397	29554878	KW	PLoS52	made the conception and design of research|supervised the experiment|performed experiments|analyzed data|interpreted results of experiments|edited and revised manuscript|approved final version of manuscript	supervised the experiment	-	Supervision	YES
5859397	29554878	KW	PLoS52	made the conception and design of research|supervised the experiment|performed experiments|analyzed data|interpreted results of experiments|edited and revised manuscript|approved final version of manuscript	performed experiments	Performed the experiments	Investigation	YES
5859397	29554878	KW	PLoS52	made the conception and design of research|supervised the experiment|performed experiments|analyzed data|interpreted results of experiments|edited and revised manuscript|approved final version of manuscript	analyzed data	Analyzed the data	Formal analysis	YES
5859397	29554878	KW	PLoS52	made the conception and design of research|supervised the experiment|performed experiments|analyzed data|interpreted results of experiments|edited and revised manuscript|approved final version of manuscript	interpreted results of experiments	Analyzed the data	Formal analysis	YES
5859397	29554878	KW	PLoS52	made the conception and design of research|supervised the experiment|performed experiments|analyzed data|interpreted results of experiments|edited and revised manuscript|approved final version of manuscript	edited and revised manuscript	Wrote the paper	Writing - Review & Editing	YES
5859397	29554878	KW	PLoS52	made the conception and design of research|supervised the experiment|performed experiments|analyzed data|interpreted results of experiments|edited and revised manuscript|approved final version of manuscript	approved final version of manuscript	-	-	NO
5859397	29554878	LB	PLoS52	interpreted results of experiments|edited and revised manuscript|approved final version of manuscript	interpreted results of experiments	Analyzed the data	Formal analysis	YES
5859397	29554878	LB	PLoS52	interpreted results of experiments|edited and revised manuscript|approved final version of manuscript	edited and revised manuscript	Wrote the paper	Writing - Review & Editing	YES
5859397	29554878	LB	PLoS52	interpreted results of experiments|edited and revised manuscript|approved final version of manuscript	approved final version of manuscript	-	-	NO
5859397	29554878	MO	PLoS52	made the conception and design of research|performed experiments|analyzed data|interpreted results of experiments|edited and revised manuscript|approved final version of manuscript	made the conception and design of research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5859397	29554878	MO	PLoS52	made the conception and design of research|performed experiments|analyzed data|interpreted results of experiments|edited and revised manuscript|approved final version of manuscript	performed experiments	Performed the experiments	Investigation	YES
5859397	29554878	MO	PLoS52	made the conception and design of research|performed experiments|analyzed data|interpreted results of experiments|edited and revised manuscript|approved final version of manuscript	analyzed data	Analyzed the data	Formal analysis	YES
5859397	29554878	MO	PLoS52	made the conception and design of research|performed experiments|analyzed data|interpreted results of experiments|edited and revised manuscript|approved final version of manuscript	interpreted results of experiments	Analyzed the data	Formal analysis	YES
5859397	29554878	MO	PLoS52	made the conception and design of research|performed experiments|analyzed data|interpreted results of experiments|edited and revised manuscript|approved final version of manuscript	edited and revised manuscript	Wrote the paper	Writing - Review & Editing	YES
5859397	29554878	MO	PLoS52	made the conception and design of research|performed experiments|analyzed data|interpreted results of experiments|edited and revised manuscript|approved final version of manuscript	approved final version of manuscript	-	-	NO
5859397	29554878	PW	PLoS52	interpreted results of experiments|contributed reagents/materials/analysis tools|edited and revised manuscript|approved final version of manuscript	interpreted results of experiments	Analyzed the data	Formal analysis	YES
5859397	29554878	PW	PLoS52	interpreted results of experiments|contributed reagents/materials/analysis tools|edited and revised manuscript|approved final version of manuscript	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5859397	29554878	PW	PLoS52	interpreted results of experiments|contributed reagents/materials/analysis tools|edited and revised manuscript|approved final version of manuscript	edited and revised manuscript	Wrote the paper	Writing - Review & Editing	YES
5859397	29554878	PW	PLoS52	interpreted results of experiments|contributed reagents/materials/analysis tools|edited and revised manuscript|approved final version of manuscript	approved final version of manuscript	-	-	NO
5859397	29554878	SP	PLoS52	interpreted results of experiments|contributed reagents/materials/analysis tools|edited and revised manuscript|approved final version of manuscript	interpreted results of experiments	Analyzed the data	Formal analysis	YES
5859397	29554878	SP	PLoS52	interpreted results of experiments|contributed reagents/materials/analysis tools|edited and revised manuscript|approved final version of manuscript	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5859397	29554878	SP	PLoS52	interpreted results of experiments|contributed reagents/materials/analysis tools|edited and revised manuscript|approved final version of manuscript	edited and revised manuscript	Wrote the paper	Writing - Review & Editing	YES
5859397	29554878	SP	PLoS52	interpreted results of experiments|contributed reagents/materials/analysis tools|edited and revised manuscript|approved final version of manuscript	approved final version of manuscript	-	-	NO
3840487	24115583	HLC	PLoS52	made the figures|conducted the experiments and analysed the data	made the figures	-	Visualization	YES
3840487	24115583	HLC	PLoS52	made the figures|conducted the experiments and analysed the data	conducted the experiments and analysed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3840487	24115583	KS	PLoS52	conceived and designed the experiments|conducted the experiments and analysed the data|generated the aav9 constructs and virus for the studies	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
3840487	24115583	KS	PLoS52	conceived and designed the experiments|conducted the experiments and analysed the data|generated the aav9 constructs and virus for the studies	conducted the experiments and analysed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3840487	24115583	KS	PLoS52	conceived and designed the experiments|conducted the experiments and analysed the data|generated the aav9 constructs and virus for the studies	generated the aav9 constructs and virus for the studies	Performed the experiments	Investigation	YES
3840487	24115583	SK	PLoS52	supervised the entire project|conceived and designed the experiments	supervised the entire project	-	Supervision	YES
3840487	24115583	SK	PLoS52	supervised the entire project|conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
3840487	24115583	SM	PLoS52	conceived and designed the experiments|conducted the experiments and analysed the data|generated the aav9 constructs and virus for the studies	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
3840487	24115583	SM	PLoS52	conceived and designed the experiments|conducted the experiments and analysed the data|generated the aav9 constructs and virus for the studies	conducted the experiments and analysed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3840487	24115583	SM	PLoS52	conceived and designed the experiments|conducted the experiments and analysed the data|generated the aav9 constructs and virus for the studies	generated the aav9 constructs and virus for the studies	Performed the experiments	Investigation	YES
3840487	24115583	STe	PLoS52	conducted the experiments and analysed the data	conducted the experiments and analysed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3840487	24115583	TY	PLoS52	conceived and designed the experiments|made the figures|conducted the experiments and analysed the data	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
3840487	24115583	TY	PLoS52	conceived and designed the experiments|made the figures|conducted the experiments and analysed the data	made the figures	-	Visualization	YES
3840487	24115583	TY	PLoS52	conceived and designed the experiments|made the figures|conducted the experiments and analysed the data	conducted the experiments and analysed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6154755	30255211	CZB	PLoS5	Conceived and designed the experiment	Conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
6154755	30255211	HTS	PLoS5	Data analysis	Data analysis	Analyzed the data	Formal analysis	YES
6154755	30255211	HXQ	PLoS5	Conceived and designed the experiment|Performed the experiments|Wrote the paper	Conceived and designed the experiment	Conceived and designed the experiments	Conceptualization|Methodology	YES
6154755	30255211	HXQ	PLoS5	Conceived and designed the experiment|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
6154755	30255211	HXQ	PLoS5	Conceived and designed the experiment|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6154755	30255211	YZS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5882989	29581404	A.M.B.	2	undertook or assisted with fieldwork|wrote the manuscript with input from all authors	undertook or assisted with fieldwork	Performed the experiments	Investigation	YES
5882989	29581404	A.M.B.	2	undertook or assisted with fieldwork|wrote the manuscript with input from all authors	wrote the manuscript with input from all authors	Wrote the paper	Writing - Original Draft	YES
5882989	29581404	All authors	2	undertook or assisted with fieldwork	undertook or assisted with fieldwork	Performed the experiments	Investigation	YES
5882989	29581404	C.J.T.	2	undertook or assisted with fieldwork|processed and analysed the data|wrote the manuscript with input from all authors	undertook or assisted with fieldwork	Performed the experiments	Investigation	YES
5882989	29581404	C.J.T.	2	undertook or assisted with fieldwork|processed and analysed the data|wrote the manuscript with input from all authors	processed and analysed the data	Analyzed the data	Data curation|Formal analysis	YES
5882989	29581404	C.J.T.	2	undertook or assisted with fieldwork|processed and analysed the data|wrote the manuscript with input from all authors	wrote the manuscript with input from all authors	Wrote the paper	Writing - Original Draft	YES
5852537	29568302	CW	2	conducted the experiments	conducted the experiments	Performed the experiments	Investigation	YES
5852537	29568302	GL	2	conducted the experiments	conducted the experiments	Performed the experiments	Investigation	YES
5852537	29568302	JH	2	prepared the plant materials and designed the experiments	prepared the plant materials and designed the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5852537	29568302	JL	2	prepared the plant materials and designed the experiments|conducted the experiments	prepared the plant materials and designed the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5852537	29568302	JL	2	prepared the plant materials and designed the experiments|conducted the experiments	conducted the experiments	Performed the experiments	Investigation	YES
5852537	29568302	MY	2	prepared the plant materials and designed the experiments	prepared the plant materials and designed the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5852537	29568302	QZ	2	conducted the experiments	conducted the experiments	Performed the experiments	Investigation	YES
5852537	29568302	SZ	2	prepared the plant materials and designed the experiments|conducted the experiments	prepared the plant materials and designed the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5852537	29568302	SZ	2	prepared the plant materials and designed the experiments|conducted the experiments	conducted the experiments	Performed the experiments	Investigation	YES
5852537	29568302	ZW	2	prepared the plant materials and designed the experiments|conducted the experiments|took the photographs|wrote the manuscript	prepared the plant materials and designed the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5852537	29568302	ZW	2	prepared the plant materials and designed the experiments|conducted the experiments|took the photographs|wrote the manuscript	conducted the experiments	Performed the experiments	Investigation	YES
5852537	29568302	ZW	2	prepared the plant materials and designed the experiments|conducted the experiments|took the photographs|wrote the manuscript	took the photographs	-	Visualization	YES
5852537	29568302	ZW	2	prepared the plant materials and designed the experiments|conducted the experiments|took the photographs|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5834898	29511564	TY	2	searched literatures, drafted the manuscript, and approved the final manuscript	searched literatures, drafted the manuscript, and approved the final manuscript	Wrote the paper	Formal analysis|Writing - Original Draft|Writing - Review & Editing	YES
4418836	25938666	AS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418836	25938666	AS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418836	25938666	AS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418836	25938666	BM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418836	25938666	BM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418836	25938666	BM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418836	25938666	BM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418836	25938666	BT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418836	25938666	BT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418836	25938666	BT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418836	25938666	BT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418836	25938666	BT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418836	25938666	JC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418836	25938666	JC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418836	25938666	JC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418836	25938666	JC	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5859408	29554864	ES	2	performed comparative genome analysis and carried out the laboratory work|contributed to the writing of the manuscript and approved the final version of the manuscript	performed comparative genome analysis and carried out the laboratory work	Performed the experiments	Investigation	YES
5859408	29554864	ES	2	performed comparative genome analysis and carried out the laboratory work|contributed to the writing of the manuscript and approved the final version of the manuscript	contributed to the writing of the manuscript and approved the final version of the manuscript	Wrote the paper	Writing - Original Draft	YES
5859408	29554864	OM	2	contributed to the writing of the manuscript and approved the final version of the manuscript	contributed to the writing of the manuscript and approved the final version of the manuscript	Wrote the paper	Writing - Original Draft	YES
2040519	17971878	EM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2040519	17971878	EM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2040519	17971878	EM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2040519	17971878	EM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2040519	17971878	JG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2040519	17971878	JG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2040519	17971878	JG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270929	25407722	Erwei Liu	7	Drafted the structural formulas	Drafted the structural formulas	Wrote the paper	Writing - Original Draft	YES
6270929	25407722	Lifeng Han	7	Revising the review critically for important intellectual content	Revising the review critically for important intellectual content	-	-	NO
6270929	25407722	Lu Qu	7	Drafted the structural formulas. Classified the chemical components	Drafted the structural formulas. Classified the chemical components	Wrote the paper	Writing - Original Draft	YES
6270929	25407722	Shiming Fang	7	References management	References management	-	-	NO
6270929	25407722	Tao Wang	7	Obtained funding. Overall responsibility	Obtained funding. Overall responsibility	-	Funding acquisition	YES
6270929	25407722	Xiaoxia Li	7	Acquisition, interpretation of data and wrote the manuscript. References management	Acquisition, interpretation of data and wrote the manuscript. References management	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6270929	25407722	Yi Zhang	7	Obtained funding. Contributed to conception and design of the review	Obtained funding. Contributed to conception and design of the review	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
6270929	25407722	Yongzhe Dong	7	Classified the pharmacological literatures	Classified the pharmacological literatures	-	-	NO
4933829	27349318	All authors	2	have participated actively in the study and approved the final manuscript	have participated actively in the study and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
4933829	27349318	CS	2	study conception, participation in the experimental design	study conception, participation in the experimental design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4933829	27349318	JBOD	2	study conception, participation in the experimental design	study conception, participation in the experimental design	Conceived and designed the experiments	Conceptualization|Methodology	YES
4933829	27349318	MUM	2	performing of experimental technical part and statistical analysis, manuscript writing	performing of experimental technical part and statistical analysis, manuscript writing	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
4418837	25938433	AB	PLoS5	Recruitment and clinical assessment of patients	Recruitment and clinical assessment of patients	Performed the experiments	Investigation	YES
4418837	25938433	AG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418837	25938433	DK	PLoS5	Recruitment and clinical assessment of patients	Recruitment and clinical assessment of patients	Performed the experiments	Investigation	YES
4418837	25938433	KB	PLoS5	Recruitment and clinical assessment of patients	Recruitment and clinical assessment of patients	Performed the experiments	Investigation	YES
4418837	25938433	RS	PLoS5	Recruitment and clinical assessment of patients	Recruitment and clinical assessment of patients	Performed the experiments	Investigation	YES
4418837	25938433	S. Banerjee	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418837	25938433	S. Basu	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418837	25938433	S. Basu	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418837	25938433	S. Basu	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418837	25938433	S. Basu	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418837	25938433	S. Majumder	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418837	25938433	S. Mukherjee	PLoS5	Recruitment and clinical assessment of patients	Recruitment and clinical assessment of patients	Performed the experiments	Investigation	YES
4418837	25938433	S. Nandy	PLoS5	Recruitment and clinical assessment of patients	Recruitment and clinical assessment of patients	Performed the experiments	Investigation	YES
4418837	25938433	S. Naskar	PLoS5	Recruitment and clinical assessment of patients	Recruitment and clinical assessment of patients	Performed the experiments	Investigation	YES
4418837	25938433	SS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418837	25938433	SS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418837	25938433	SS	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5852684	29568303	BD	2	designed the research|were involved with substantial contributions in refining the methodology, writing, and reviewing the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
5852684	29568303	BD	2	designed the research|were involved with substantial contributions in refining the methodology, writing, and reviewing the manuscript	were involved with substantial contributions in refining the methodology, writing, and reviewing the manuscript	Performed the experiments|Wrote the paper	Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5852684	29568303	JK	2	were involved with substantial contributions in refining the methodology, writing, and reviewing the manuscript	were involved with substantial contributions in refining the methodology, writing, and reviewing the manuscript	Performed the experiments|Wrote the paper	Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5852684	29568303	LM	2	were involved with substantial contributions in refining the methodology, writing, and reviewing the manuscript	were involved with substantial contributions in refining the methodology, writing, and reviewing the manuscript	Performed the experiments|Wrote the paper	Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5852684	29568303	MZ	2	designed the research|performed the data analysis and presentation|were involved with substantial contributions in refining the methodology, writing, and reviewing the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
5852684	29568303	MZ	2	designed the research|performed the data analysis and presentation|were involved with substantial contributions in refining the methodology, writing, and reviewing the manuscript	performed the data analysis and presentation	Analyzed the data	Formal analysis	YES
5852684	29568303	MZ	2	designed the research|performed the data analysis and presentation|were involved with substantial contributions in refining the methodology, writing, and reviewing the manuscript	were involved with substantial contributions in refining the methodology, writing, and reviewing the manuscript	Performed the experiments|Wrote the paper	Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5852684	29568303	SB	2	were involved with substantial contributions in refining the methodology, writing, and reviewing the manuscript	were involved with substantial contributions in refining the methodology, writing, and reviewing the manuscript	Performed the experiments|Wrote the paper	Methodology|Writing - Original Draft|Writing - Review & Editing	YES
6160374	30264211	APO	2	proposed the study plan, with the overall approach, contributed to critical discussion of the results and reviewed the manuscript	proposed the study plan, with the overall approach, contributed to critical discussion of the results and reviewed the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
6160374	30264211	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6160374	30264211	CG	2	performed the laboratory work and wrote the first version of the manuscript	performed the laboratory work and wrote the first version of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6160374	30264211	CT	2	contributed with their expertise in chromatography techniques both for study plan design, results discussion and critical review of the final manuscript	contributed with their expertise in chromatography techniques both for study plan design, results discussion and critical review of the final manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
6160374	30264211	GGD	2	proposed the study plan, with the overall approach, contributed to critical discussion of the results and reviewed the manuscript	proposed the study plan, with the overall approach, contributed to critical discussion of the results and reviewed the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
6160374	30264211	JAQ	2	contributed with their expertise in chromatography techniques both for study plan design, results discussion and critical review of the final manuscript	contributed with their expertise in chromatography techniques both for study plan design, results discussion and critical review of the final manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Review & Editing	YES
6160374	30264211	JMO	2	proposed the study plan, with the overall approach, contributed to critical discussion of the results and reviewed the manuscript	proposed the study plan, with the overall approach, contributed to critical discussion of the results and reviewed the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
6160374	30264211	RPO	2	contributed with her expertise in some laboratory tasks and critical review of the manuscript	contributed with her expertise in some laboratory tasks and critical review of the manuscript	Wrote the paper	Writing - Review & Editing	YES
6160374	30264211	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
3840488	24127404	BO	2	assisted reporter assay and chip	assisted reporter assay and chip	Performed the experiments	Investigation	YES
3840488	24127404	DK	2	generated alk5 inhibitors	generated alk5 inhibitors	Performed the experiments	Investigation	YES
3840488	24127404	IL	2	supported the project and managed the mouse colonies and animal experiments	supported the project and managed the mouse colonies and animal experiments	Performed the experiments	Investigation|Project administration	YES
3840488	24127404	JJ	2	performed flowcytometry	performed flowcytometry	Performed the experiments	Investigation	YES
3840488	24127404	JSH	2	supported the project and managed the mouse colonies and animal experiments	supported the project and managed the mouse colonies and animal experiments	Performed the experiments	Investigation|Project administration	YES
3840488	24127404	JY	2	designed and performed the experiments, analysed data and wrote the manuscript	designed and performed the experiments, analysed data and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
3840488	24127404	KJ	2	performed histological analysis	performed histological analysis	Performed the experiments	Investigation	YES
3840488	24127404	KS	2	supported the project and managed the mouse colonies and animal experiments	supported the project and managed the mouse colonies and animal experiments	Performed the experiments	Investigation|Project administration	YES
3840488	24127404	MK	2	supported the project and managed the mouse colonies and animal experiments|performed histological analysis	supported the project and managed the mouse colonies and animal experiments	Performed the experiments	Investigation|Project administration	YES
3840488	24127404	MK	2	supported the project and managed the mouse colonies and animal experiments|performed histological analysis	performed histological analysis	Performed the experiments	Investigation	YES
3840488	24127404	MM	2	conceived the project idea, designed the experiments, supervised the project and wrote the manuscript	conceived the project idea, designed the experiments, supervised the project and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Supervision|Writing - Original Draft	YES
3840488	24127404	OK	2	assisted reporter assay and chip	assisted reporter assay and chip	Performed the experiments	Investigation	YES
3840488	24127404	SHP	2	performed ubiquitin studies	performed ubiquitin studies	Performed the experiments	Investigation	YES
3840488	24127404	SMJ	2	performed ubiquitin studies	performed ubiquitin studies	Performed the experiments	Investigation	YES
3840488	24127404	SN	2	supported the project and managed the mouse colonies and animal experiments	supported the project and managed the mouse colonies and animal experiments	Performed the experiments	Investigation|Project administration	YES
3840488	24127404	SP	2	performed histological analysis	performed histological analysis	Performed the experiments	Investigation	YES
3840488	24127404	TS	2	supported the project and managed the mouse colonies and animal experiments	supported the project and managed the mouse colonies and animal experiments	Performed the experiments	Investigation|Project administration	YES
3840488	24127404	TY	2	supported the project and managed the mouse colonies and animal experiments	supported the project and managed the mouse colonies and animal experiments	Performed the experiments	Investigation|Project administration	YES
5882995	29531144	A.B.B.	2	performed igg assays and conducted fieldwork	performed igg assays and conducted fieldwork	Performed the experiments	Investigation	YES
5882995	29531144	A.T.G.	2	helped design the study and contributed to data analysis	helped design the study and contributed to data analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5882995	29531144	All the authors	2	contributed to manuscript revisions and gave their final approval for publication	contributed to manuscript revisions and gave their final approval for publication	Wrote the paper	Writing - Review & Editing	YES
5882995	29531144	D.G.S.	2	helped design the study and secure funding, facilitated field logistics and contributed to data analysis	helped design the study and secure funding, facilitated field logistics and contributed to data analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Funding acquisition|Methodology|Project administration	YES
5882995	29531144	G.A.C.	2	helped design the study, provided immunological protocols and contributed to data analysis	helped design the study, provided immunological protocols and contributed to data analysis	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Methodology|Resources	YES
5882995	29531144	J.E.C.	2	facilitated field logistics and conducted fieldwork	facilitated field logistics and conducted fieldwork	Performed the experiments	Investigation|Project administration	YES
5882995	29531144	K.J.N.	2	provided laboratory space and reagents for igg assays and contributed to data analysis	provided laboratory space and reagents for igg assays and contributed to data analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5882995	29531144	M.B.F.	2	facilitated field logistics and conducted fieldwork	facilitated field logistics and conducted fieldwork	Performed the experiments	Investigation|Project administration	YES
5882995	29531144	M.S.C.	2	performed extracellular haemoparasite screening	performed extracellular haemoparasite screening	Performed the experiments	Investigation	YES
5882995	29531144	N.B.S.	2	facilitated field logistics and conducted fieldwork	facilitated field logistics and conducted fieldwork	Performed the experiments	Investigation|Project administration	YES
5882995	29531144	PCR	2	and sequencing	and sequencing	Performed the experiments	Investigation	YES
5882995	29531144	S.A.	2	helped design the study and secure funding, and contributed to data analysis	helped design the study and secure funding, and contributed to data analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Funding acquisition|Methodology	YES
5882995	29531144	S.E.R.	2	facilitated field logistics and conducted fieldwork	facilitated field logistics and conducted fieldwork	Performed the experiments	Investigation|Project administration	YES
5836415	29515808	CN	2	worked equally on writing and editing the manuscript	worked equally on writing and editing the manuscript	Performed the experiments|Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5836415	29515808	KP	2	worked equally on writing and editing the manuscript	worked equally on writing and editing the manuscript	Performed the experiments|Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5836415	29515808	NK	2	worked equally on writing and editing the manuscript	worked equally on writing and editing the manuscript	Performed the experiments|Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5836415	29515808	PN	2	worked equally on writing and editing the manuscript	worked equally on writing and editing the manuscript	Performed the experiments|Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5836415	29515808	SY	2	worked equally on writing and editing the manuscript	worked equally on writing and editing the manuscript	Performed the experiments|Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5859436	29558883	GL	PLoS52	designed research|analyzed data|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
5859436	29558883	GL	PLoS52	designed research|analyzed data|wrote the paper	analyzed data	Analyzed the data	Formal analysis	YES
5859436	29558883	GL	PLoS52	designed research|analyzed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5859436	29558883	GW	PLoS52	performed research|analyzed data|wrote the paper	performed research	Performed the experiments	Investigation	YES
5859436	29558883	GW	PLoS52	performed research|analyzed data|wrote the paper	analyzed data	Analyzed the data	Formal analysis	YES
5859436	29558883	GW	PLoS52	performed research|analyzed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5859436	29558883	JL	PLoS52	performed research|analyzed data|wrote the paper	performed research	Performed the experiments	Investigation	YES
5859436	29558883	JL	PLoS52	performed research|analyzed data|wrote the paper	analyzed data	Analyzed the data	Formal analysis	YES
5859436	29558883	JL	PLoS52	performed research|analyzed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5859436	29558883	LS	PLoS52	designed research|analyzed data|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
5859436	29558883	LS	PLoS52	designed research|analyzed data|wrote the paper	analyzed data	Analyzed the data	Formal analysis	YES
5859436	29558883	LS	PLoS52	designed research|analyzed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5859436	29558883	PM	PLoS52	contributed new reagents or analytic tools|analyzed data|wrote the paper	contributed new reagents or analytic tools	Contributed reagents/materials/analysis tools	Resources	YES
5859436	29558883	PM	PLoS52	contributed new reagents or analytic tools|analyzed data|wrote the paper	analyzed data	Analyzed the data	Formal analysis	YES
5859436	29558883	PM	PLoS52	contributed new reagents or analytic tools|analyzed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5859436	29558883	QL	PLoS52	performed research|analyzed data|wrote the paper	performed research	Performed the experiments	Investigation	YES
5859436	29558883	QL	PLoS52	performed research|analyzed data|wrote the paper	analyzed data	Analyzed the data	Formal analysis	YES
5859436	29558883	QL	PLoS52	performed research|analyzed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5859436	29558883	WL	PLoS52	performed research|analyzed data|wrote the paper	performed research	Performed the experiments	Investigation	YES
5859436	29558883	WL	PLoS52	performed research|analyzed data|wrote the paper	analyzed data	Analyzed the data	Formal analysis	YES
5859436	29558883	WL	PLoS52	performed research|analyzed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5859436	29558883	ZG	PLoS52	contributed new reagents or analytic tools|analyzed data|wrote the paper	contributed new reagents or analytic tools	Contributed reagents/materials/analysis tools	Resources	YES
5859436	29558883	ZG	PLoS52	contributed new reagents or analytic tools|analyzed data|wrote the paper	analyzed data	Analyzed the data	Formal analysis	YES
5859436	29558883	ZG	PLoS52	contributed new reagents or analytic tools|analyzed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4933831	27349320	All authors	2	contributed to this work and approved the final version of the paper	contributed to this work and approved the final version of the paper	-	-	NO
4933831	27349320	CB	2	collection of fascia from volunteers patients	collection of fascia from volunteers patients	Performed the experiments	Investigation	YES
4933831	27349320	CF	2	manuscript writing, isolation, culture cells, rt pcr	manuscript writing, isolation, culture cells, rt pcr	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
4933831	27349320	CS	2	contribution to manuscript writing and editing, study coordination	contribution to manuscript writing and editing, study coordination	Wrote the paper	Project administration|Writing - Original Draft|Writing - Review & Editing	YES
4933831	27349320	MMS	2	contribution to cells isolation and immunostaining	contribution to cells isolation and immunostaining	Performed the experiments	Investigation	YES
4933831	27349320	RDC	2	contribution to manuscript writing and editing, study coordination	contribution to manuscript writing and editing, study coordination	Wrote the paper	Project administration|Writing - Original Draft|Writing - Review & Editing	YES
4674665	26693489	Xiang Yan	2	are equal contributors	are equal contributors	-	-	NO
4674665	26693489	Zhen-Zhen Zhang	2	are equal contributors	are equal contributors	-	-	NO
2040520	17971869	CT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2040520	17971869	CT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2040520	17971869	CT	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2040520	17971869	ES	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
2040520	17971869	ES	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2040520	17971869	HM	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2040520	17971869	HM	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2040520	17971869	KH	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
2040520	17971869	KH	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2040520	17971869	KM	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
2040520	17971869	KM	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2040520	17971869	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2040520	17971869	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2040520	17971869	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2040520	17971869	ML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2040520	17971869	PH	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2040520	17971869	PH	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2040520	17971869	TS	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5853165	29568306	AK	2	assisted with the measurement set-up and provided technical support	assisted with the measurement set-up and provided technical support	Performed the experiments	Investigation	YES
5853165	29568306	All of the authors	2	have contributed to the finalizing of the manuscript	have contributed to the finalizing of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5853165	29568306	HH	2	arranged all the required resources, supervised the experiment, and participated in the writing of the manuscript	arranged all the required resources, supervised the experiment, and participated in the writing of the manuscript	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Supervision|Writing - Original Draft	YES
5853165	29568306	HK	2	contributed to the design of the experiment, gave technical advice, and commented on the manuscript	contributed to the design of the experiment, gave technical advice, and commented on the manuscript	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5853165	29568306	JH	2	arranged all the required resources, supervised the experiment, and participated in the writing of the manuscript	arranged all the required resources, supervised the experiment, and participated in the writing of the manuscript	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Supervision|Writing - Original Draft	YES
5853165	29568306	JS	2	contributed to the laboratory analysis and writing of the manuscript	contributed to the laboratory analysis and writing of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5853165	29568306	MH	2	arranged all the required resources, supervised the experiment, and participated in the writing of the manuscript	arranged all the required resources, supervised the experiment, and participated in the writing of the manuscript	Contributed reagents/materials/analysis tools|Wrote the paper	Resources|Supervision|Writing - Original Draft	YES
5853165	29568306	MV	2	assisted in designing the experiment, statistical analysis, and the writing of the manuscript	assisted in designing the experiment, statistical analysis, and the writing of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5853165	29568306	RL	2	contributed to the design of the experiment, data collection, and commented on the manuscript	contributed to the design of the experiment, data collection, and commented on the manuscript	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Methodology|Resources	YES
5853165	29568306	SJ	2	designed the experiment, conducted data processing and statistical analysis, and wrote the manuscript	designed the experiment, conducted data processing and statistical analysis, and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Data curation|Formal analysis|Methodology|Writing - Original Draft	YES
4418838	25938454	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418838	25938454	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418838	25938454	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418838	25938454	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418838	25938454	JK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6160375	30264182	Both authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6160375	30264182	CBM	2	designed the study, conducted the laboratory work, analyzed the data and wrote the manuscript	designed the study, conducted the laboratory work, analyzed the data and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
6160375	30264182	SK	2	supervised the work and critically reviewed the manuscript	supervised the work and critically reviewed the manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
6160375	30264182	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5838933	29556399	HM	2	is fully invloved in writing of the manuscript	is fully invloved in writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5859443	29554868	DCB	2	designed the research and wrote the manuscript	designed the research and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5859443	29554868	QG	2	designed the research and wrote the manuscript|performed the research	designed the research and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5859443	29554868	QG	2	designed the research and wrote the manuscript|performed the research	performed the research	Performed the experiments	Investigation	YES
3840489	24039159	DS	2	contributed to experiments and performed data analysis	contributed to experiments and performed data analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
3840489	24039159	JL	2	contributed to experiments and performed data analysis	contributed to experiments and performed data analysis	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
3840489	24039159	KB	2	performed major portion of experiments, analysed data and wrote the manuscript	performed major portion of experiments, analysed data and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3840489	24039159	RK	2	designed and supervised the study and wrote the manuscript	designed and supervised the study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Original Draft	YES
3840489	24039159	RS	2	contributed to the bioinformatics part of the study	contributed to the bioinformatics part of the study	-	Formal analysis	YES
3840489	24039159	VPS	2	contributed to the bioinformatics part of the study	contributed to the bioinformatics part of the study	-	Formal analysis	YES
4372082	25002256	All authors	2	have given approval to the final version of the manuscript	have given approval to the final version of the manuscript	-	-	NO
6270931	24786848	HD	2	carried out all experiments|performed data analysis and drafted the manuscript	carried out all experiments	Performed the experiments	Investigation	YES
6270931	24786848	HD	2	carried out all experiments|performed data analysis and drafted the manuscript	performed data analysis and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6270931	24786848	HR	2	carried out all experiments	carried out all experiments	Performed the experiments	Investigation	YES
6270931	24786848	MJ	2	carried out all experiments	carried out all experiments	Performed the experiments	Investigation	YES
6270931	24786848	XZ	2	conceived the design of the study, supervised all experiments and helped to draft the manuscript	conceived the design of the study, supervised all experiments and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Supervision|Writing - Original Draft	YES
6270931	24786848	ZG	2	carried out all experiments|performed data analysis and drafted the manuscript	carried out all experiments	Performed the experiments	Investigation	YES
6270931	24786848	ZG	2	carried out all experiments|performed data analysis and drafted the manuscript	performed data analysis and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
3913529	24574919	Bing-You Yang	2	equally contributed to this work	equally contributed to this work	-	-	NO
3913529	24574919	Jun Liang	2	equally contributed to this work	equally contributed to this work	-	-	NO
3913529	24574919	Yong-Gang Xia	2	equally contributed to this work	equally contributed to this work	-	-	NO
2040521	17971881	AC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2040521	17971881	AC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2040521	17971881	AC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2040521	17971881	AM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2040521	17971881	AM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2040521	17971881	AM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2040521	17971881	BL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2040521	17971881	BL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2040521	17971881	BL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2040521	17971881	JH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2040521	17971881	JH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2040521	17971881	JH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2040521	17971881	PC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2040521	17971881	PC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2040521	17971881	PC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2040521	17971881	RJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2040521	17971881	RJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2040521	17971881	RJ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2040521	17971881	SH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2040521	17971881	SH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2040521	17971881	SH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5882997	29531146	A.A.C.	2	conducted wild bird post-mortem examinations, coordinated diagnostic testing, obtained funding and coordinated the surveillance programme	conducted wild bird post-mortem examinations, coordinated diagnostic testing, obtained funding and coordinated the surveillance programme	Performed the experiments	Funding acquisition|Investigation|Project administration|Software	YES
5882997	29531146	All the authors	2	contributed to the manuscript preparation	contributed to the manuscript preparation	Wrote the paper	Writing - Original Draft	YES
5882997	29531146	B.L.	2	conducted wild bird post-mortem examinations, coordinated diagnostic testing, obtained funding and coordinated the surveillance programme	conducted wild bird post-mortem examinations, coordinated diagnostic testing, obtained funding and coordinated the surveillance programme	Performed the experiments	Funding acquisition|Investigation|Project administration|Software	YES
5882997	29531146	Garden BirdWatch	2	scheme and the systematic disease surveillance	scheme and the systematic disease surveillance	-	-	NO
5882997	29531146	R.A.R.	2	conducted epidemiological and population monitoring analyses	conducted epidemiological and population monitoring analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Supervision	YES
5882997	29531146	S.M.	2	conducted the mycotoxin analyses	conducted the mycotoxin analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5853159	29564137	AS	2	analyzed the data from electrical impedance tomography|contributed to the interpretation of the data	analyzed the data from electrical impedance tomography	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5853159	29564137	AS	2	analyzed the data from electrical impedance tomography|contributed to the interpretation of the data	contributed to the interpretation of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5853159	29564137	All authors	2	provided comments on the report at various stages of development and read and approved the final manuscript	provided comments on the report at various stages of development and read and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5853159	29564137	ET	2	analyzed the data from electrical impedance tomography|contributed to the interpretation of the data	analyzed the data from electrical impedance tomography	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5853159	29564137	ET	2	analyzed the data from electrical impedance tomography|contributed to the interpretation of the data	contributed to the interpretation of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5853159	29564137	HY	2	were responsible for the patient care and data collection	were responsible for the patient care and data collection	Performed the experiments	Investigation	YES
5853159	29564137	MH	2	were responsible for the patient care and data collection	were responsible for the patient care and data collection	Performed the experiments	Investigation	YES
5853159	29564137	SH	2	were responsible for the patient care and data collection	were responsible for the patient care and data collection	Performed the experiments	Investigation	YES
5853159	29564137	TK	2	coordinated the study|were responsible for the patient care and data collection|contributed to the interpretation of the data	coordinated the study	-	Project administration	YES
5853159	29564137	TK	2	coordinated the study|were responsible for the patient care and data collection|contributed to the interpretation of the data	were responsible for the patient care and data collection	Performed the experiments	Investigation	YES
5853159	29564137	TK	2	coordinated the study|were responsible for the patient care and data collection|contributed to the interpretation of the data	contributed to the interpretation of the data	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
5853265	29568305	All the authors	2	participated during the fieldwork for the acquisition of flower counts as well as in the writing of thispublication	participated during the fieldwork for the acquisition of flower counts as well as in the writing of thispublication	Performed the experiments|Wrote the paper	Investigation	YES
5853265	29568305	Remote Sensing	2	and methodology	and methodology	Performed the experiments	Methodology	YES
6163121	30269298	All authors	2	were involved in data interpretation and the writing of the paper|read and approved the final manuscript	were involved in data interpretation and the writing of the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6163121	30269298	All authors	2	were involved in data interpretation and the writing of the paper|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6163121	30269298	BIP	2	designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
6163121	30269298	JFD	2	designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
6163121	30269298	ORA	2	designed the research|preformed all the experiments and data analysis	designed the research	Conceived and designed the experiments	Methodology	YES
6163121	30269298	ORA	2	designed the research|preformed all the experiments and data analysis	preformed all the experiments and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6163121	30269298	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5859498	29554870	ALG	2	designed experiments|acquired the data|analyzed data	designed experiments	Conceived and designed the experiments	Methodology	YES
5859498	29554870	ALG	2	designed experiments|acquired the data|analyzed data	acquired the data	Performed the experiments	Investigation	YES
5859498	29554870	ALG	2	designed experiments|acquired the data|analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5859498	29554870	All authors	2	helped draft the final manuscript and approved its submission	helped draft the final manuscript and approved its submission	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5859498	29554870	DJH	2	acquired the data	acquired the data	Performed the experiments	Investigation	YES
5859498	29554870	DMK	2	provided samples|provided samples|helped interpret the data and provided critical feedback on manuscript	provided samples	Contributed reagents/materials/analysis tools	Resources	YES
5859498	29554870	DMK	2	provided samples|provided samples|helped interpret the data and provided critical feedback on manuscript	provided samples	Contributed reagents/materials/analysis tools	Resources	YES
5859498	29554870	DMK	2	provided samples|provided samples|helped interpret the data and provided critical feedback on manuscript	helped interpret the data and provided critical feedback on manuscript	Analyzed the data	Formal analysis	YES
5859498	29554870	DPD	2	acquired the data	acquired the data	Performed the experiments	Investigation	YES
5859498	29554870	DZ	2	helped interpret the data and provided critical feedback on manuscript	helped interpret the data and provided critical feedback on manuscript	Analyzed the data	Formal analysis	YES
5859498	29554870	GMK	2	acquired the data|analyzed data	acquired the data	Performed the experiments	Investigation	YES
5859498	29554870	GMK	2	acquired the data|analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5859498	29554870	HX	2	acquired the data	acquired the data	Performed the experiments	Investigation	YES
5859498	29554870	JAH	2	provided samples	provided samples	Contributed reagents/materials/analysis tools	Resources	YES
5859498	29554870	JG	2	acquired the data	acquired the data	Performed the experiments	Investigation	YES
5859498	29554870	KRJ	2	designed experiments	designed experiments	Conceived and designed the experiments	Methodology	YES
5859498	29554870	LC	2	provided samples	provided samples	Contributed reagents/materials/analysis tools	Resources	YES
5859498	29554870	MB	2	provided samples	provided samples	Contributed reagents/materials/analysis tools	Resources	YES
5859498	29554870	MC	2	provided samples	provided samples	Contributed reagents/materials/analysis tools	Resources	YES
5859498	29554870	MH	2	acquired the data	acquired the data	Performed the experiments	Investigation	YES
5859498	29554870	PR	2	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
5859498	29554870	RHS	2	acquired the data	acquired the data	Performed the experiments	Investigation	YES
5859498	29554870	SG	2	provided samples	provided samples	Contributed reagents/materials/analysis tools	Resources	YES
5859498	29554870	TN	2	acquired the data	acquired the data	Performed the experiments	Investigation	YES
5859498	29554870	TY	2	provided samples	provided samples	Contributed reagents/materials/analysis tools	Resources	YES
5859498	29554870	VP	2	acquired the data	acquired the data	Performed the experiments	Investigation	YES
2042512	17971863	DM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2042512	17971863	DM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2042512	17971863	DM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2042512	17971863	JC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
2042512	17971863	JC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2042512	17971863	RN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2042512	17971863	RN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2042512	17971863	RN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2042512	17971863	RN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2042512	17971863	RN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4933834	27349323	EA	2	experiments performing|data analysis	experiments performing	Performed the experiments	Investigation	YES
4933834	27349323	EA	2	experiments performing|data analysis	data analysis	Analyzed the data	Formal analysis	YES
4933834	27349323	FL	2	experiments performing	experiments performing	Performed the experiments	Investigation	YES
4933834	27349323	JP	2	data analysis	data analysis	Analyzed the data	Formal analysis	YES
4933834	27349323	MG	2	experiments performing	experiments performing	Performed the experiments	Investigation	YES
4933834	27349323	RFD	2	data analysis	data analysis	Analyzed the data	Formal analysis	YES
4933834	27349323	SB	2	experiments concept and design, paper writing|data analysis	experiments concept and design, paper writing	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology	YES
4933834	27349323	SB	2	experiments concept and design, paper writing|data analysis	data analysis	Analyzed the data	Formal analysis	YES
3840490	24115572	AI	2	designed and performed all experiments with mice, contributed to data analysis and paper writing	designed and performed all experiments with mice, contributed to data analysis and paper writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology	YES
3840490	24115572	ARN	2	supervised the project, designed experiments, analysed data and wrote the paper	supervised the project, designed experiments, analysed data and wrote the paper	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Supervision|Writing - Original Draft	YES
3840490	24115572	BC	2	performed experiments with cell lines	performed experiments with cell lines	Performed the experiments	Investigation	YES
3840490	24115572	ID	2	participated in the early stages of the project, designing experiments and analysing data	participated in the early stages of the project, designing experiments and analysing data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
3840490	24115572	LP	2	designed and performed most experiments with cell lines, analysed data and wrote the paper	designed and performed most experiments with cell lines, analysed data and wrote the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4372083	25723840	B.P.	2	contributed equally to this work	contributed equally to this work	-	-	NO
4372083	25723840	C.Z.	2	contributed equally to this work	contributed equally to this work	-	-	NO
5855997	29568527	All	2	were involved in the critical revision for the intellectual content and read and approved the final manuscript	were involved in the critical revision for the intellectual content and read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5855997	29568527	All authors	2	contributed to the experimental conception and design	contributed to the experimental conception and design	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
5855997	29568527	BL	2	were involved in the clinical and experimental data analysis and manuscript drafting	were involved in the clinical and experimental data analysis and manuscript drafting	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5855997	29568527	CMD	2	was responsible for the patient enrolment, clinical and experimental data acquisition and analysis, and manuscript drafting	was responsible for the patient enrolment, clinical and experimental data acquisition and analysis, and manuscript drafting	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5855997	29568527	DSH	2	were involved in the clinical and experimental data analysis and manuscript drafting	were involved in the clinical and experimental data analysis and manuscript drafting	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5855997	29568527	JSR	2	participated in the experimental data analysis	participated in the experimental data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5855997	29568527	XO	2	were involved in the clinical and experimental data analysis and manuscript drafting	were involved in the clinical and experimental data analysis and manuscript drafting	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
4418840	25938235	HHB	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418840	25938235	HHB	PLoS5	Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418840	25938235	KNW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418840	25938235	KNW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418840	25938235	KNW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418840	25938235	KNW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418840	25938235	MK	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418840	25938235	MK	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5882998	29531147	D.T.C.C.	2	jointly conceived, designed and wrote the paper	jointly conceived, designed and wrote the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5882998	29531147	K.J.G.	2	jointly conceived, designed and wrote the paper	jointly conceived, designed and wrote the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
6270932	25268712	Shwu-Jen Wu	PLoS52	designed and performed research, and also analyzed the data|wrote the paper	designed and performed research, and also analyzed the data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
6270932	25268712	Shwu-Jen Wu	PLoS52	designed and performed research, and also analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270932	25268712	Yu-Yi Chan	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
2042513	17987108	CC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2042513	17987108	CC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2042513	17987108	CC	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2042513	17987108	LG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2042513	17987108	LG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2042513	17987108	LG	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2042513	17987108	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2042513	17987108	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2042513	17987108	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2042513	17987108	MK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2042513	17987108	PA	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2042513	17987108	PL	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2042513	17987108	PL	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2042513	17987108	PL	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2042513	17987108	VL	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
6163125	30269246	Academic Backbone Project	2	of northeast agricultural university	of northeast agricultural university	-	-	NO
6163125	30269246	All	2	data generated or analyzed during this study are included in this published article	data generated or analyzed during this study are included in this published article	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6163125	30269246	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6163125	30269246	CM	2	designed the entire research project|reviewed the manuscript	designed the entire research project	Conceived and designed the experiments	Methodology	YES
6163125	30269246	CM	2	designed the entire research project|reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
6163125	30269246	SC	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
6163125	30269246	SF	2	designed the experimental details and performed the experiments|prepared the manuscript|revised the manuscript	designed the experimental details and performed the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6163125	30269246	SF	2	designed the experimental details and performed the experiments|prepared the manuscript|revised the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
6163125	30269246	SF	2	designed the experimental details and performed the experiments|prepared the manuscript|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
6163125	30269246	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
6163125	30269246	XJ	2	designed the experimental details and performed the experiments|revised the manuscript	designed the experimental details and performed the experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
6163125	30269246	XJ	2	designed the experimental details and performed the experiments|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
6163125	30269246	XY	2	provided the required strains for the experiment	provided the required strains for the experiment	Performed the experiments|Contributed reagents/materials/analysis tools	Investigation|Resources	YES
6163125	30269246	YJ	2	designed the entire research project|reviewed the manuscript	designed the entire research project	Conceived and designed the experiments	Methodology	YES
6163125	30269246	YJ	2	designed the entire research project|reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
6163125	30269246	YZ	2	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5854652	29593769	BS	2	conceived and conducted the experiments, processed the data, and revised the manuscript	conceived and conducted the experiments, processed the data, and revised the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Data curation|Investigation|Writing - Review & Editing	YES
5854652	29593769	CX	2	conceived and conducted the experiments, processed the data, and revised the manuscript	conceived and conducted the experiments, processed the data, and revised the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Data curation|Investigation|Writing - Review & Editing	YES
5854652	29593769	GX	2	designed the methods and experiments, carried out the experiments, analyzed the data, and wrote the manuscript	designed the methods and experiments, carried out the experiments, analyzed the data, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5854652	29593769	HC	2	grown the plants and detected the phenotypes|performed the genotype analysis	grown the plants and detected the phenotypes	Performed the experiments	Investigation	YES
5854652	29593769	HC	2	grown the plants and detected the phenotypes|performed the genotype analysis	performed the genotype analysis	Performed the experiments	Investigation	YES
5854652	29593769	HW	2	grown the plants and detected the phenotypes	grown the plants and detected the phenotypes	Performed the experiments	Investigation	YES
5854652	29593769	JL	2	conceived and conducted the experiments, processed the data, and revised the manuscript	conceived and conducted the experiments, processed the data, and revised the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Data curation|Investigation|Writing - Review & Editing	YES
5854652	29593769	WH	2	grown the plants and detected the phenotypes|performed the genotype analysis	grown the plants and detected the phenotypes	Performed the experiments	Investigation	YES
5854652	29593769	WH	2	grown the plants and detected the phenotypes|performed the genotype analysis	performed the genotype analysis	Performed the experiments	Investigation	YES
5854652	29593769	WT	2	grown the plants and detected the phenotypes	grown the plants and detected the phenotypes	Performed the experiments	Investigation	YES
5854652	29593769	XZ	2	grown the plants and detected the phenotypes	grown the plants and detected the phenotypes	Performed the experiments	Investigation	YES
2042515	17987122	BW	PLoS5	Principal investigator	Principal investigator	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
2042515	17987122	DA	PLoS5	Principal investigator	Principal investigator	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
2042515	17987122	EP	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2042515	17987122	JG	PLoS5	Principal investigator	Principal investigator	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
2042515	17987122	MC	PLoS5	Principal investigator	Principal investigator	Conceived and designed the experiments	Conceptualization|Funding acquisition	YES
2042515	17987122	MT	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2042515	17987122	MT	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2042515	17987122	PB	PLoS5	Supervised data analysis	Supervised data analysis	Analyzed the data	Formal analysis|Supervision	YES
2042515	17987122	SC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2042515	17987122	SC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2042515	17987122	SC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418843	25938779	HJK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Discussed idea in this paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418843	25938779	HJK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Discussed idea in this paper	Performed the experiments	Performed the experiments	Investigation	YES
4418843	25938779	HJK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Discussed idea in this paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418843	25938779	HJK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Discussed idea in this paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418843	25938779	HJK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Discussed idea in this paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418843	25938779	HJK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Discussed idea in this paper	Discussed idea in this paper	Conceived and designed the experiments	Conceptualization	YES
4418843	25938779	KIC	PLoS5	Discussed idea in this paper	Discussed idea in this paper	Conceived and designed the experiments	Conceptualization	YES
4418843	25938779	SIC	PLoS5	Wrote the paper|Discussed idea in this paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418843	25938779	SIC	PLoS5	Wrote the paper|Discussed idea in this paper	Discussed idea in this paper	Conceived and designed the experiments	Conceptualization	YES
5882999	29531148	All the authors	2	provided critical feedback and contributed to the content	provided critical feedback and contributed to the content	-	-	NO
5882999	29531148	B.M.S.	2	provided critical feedback and contributed to the content	provided critical feedback and contributed to the content	-	-	NO
5882999	29531148	E.K.C.	2	provided critical feedback and contributed to the content	provided critical feedback and contributed to the content	-	-	NO
5882999	29531148	J.D.R.	2	provided critical feedback and contributed to the content	provided critical feedback and contributed to the content	-	-	NO
5882999	29531148	P.C.C.	2	conceived the idea for this article	conceived the idea for this article	Conceived and designed the experiments	Conceptualization	YES
5882999	29531148	R.K.F.	2	provided critical feedback and contributed to the content	provided critical feedback and contributed to the content	-	-	NO
3840491	24142887	BC	2	designed and performed experiments	designed and performed experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3840491	24142887	CA	2	designed and performed experiments	designed and performed experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3840491	24142887	CC	2	designed the study and analysed data	designed the study and analysed data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
3840491	24142887	ED	2	designed and performed experiments	designed and performed experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3840491	24142887	EG	2	designed and performed experiments	designed and performed experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3840491	24142887	EN	2	designed and performed experiments	designed and performed experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3840491	24142887	FBC	2	collected samples and analysed data	collected samples and analysed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3840491	24142887	FS	2	designed the study, performed experiments, analysed data and wrote the paper	designed the study, performed experiments, analysed data and wrote the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
3840491	24142887	IFC	2	designed and performed experiments	designed and performed experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3840491	24142887	J-AS	2	collected samples and analysed data	collected samples and analysed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3840491	24142887	JLB	2	collected samples and analysed data	collected samples and analysed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3840491	24142887	LP	2	designed and performed experiments	designed and performed experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3840491	24142887	NS	2	designed and performed experiments	designed and performed experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3840491	24142887	NVR	2	designed and performed experiments	designed and performed experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3840491	24142887	OL	2	designed and performed experiments	designed and performed experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3840491	24142887	SC	2	designed and performed experiments	designed and performed experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3840491	24142887	SJH	2	designed and performed experiments	designed and performed experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3840491	24142887	SL	2	designed and performed experiments	designed and performed experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3840491	24142887	WR	2	designed and performed experiments	designed and performed experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3840491	24142887	XG	2	designed and performed experiments	designed and performed experiments	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5856388	29568528	TN	2	wrote the main manuscript	wrote the main manuscript	Wrote the paper	Writing - Original Draft	YES
5856388	29568528	YT	2	critically reviewed and revised the manuscript for intellectual content	critically reviewed and revised the manuscript for intellectual content	Wrote the paper	Writing - Review & Editing	YES
5859501	29558892	CE	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5859501	29558892	TS	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5062631	27734991	AVS	2	study design, experimental procedures, histochemical and immunohistochemical processing, microscopic analysis, data collection, figures preparation, manuscript drafting	study design, experimental procedures, histochemical and immunohistochemical processing, microscopic analysis, data collection, figures preparation, manuscript drafting	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Formal analysis|Investigation|Methodology|Visualization|Writing - Original Draft	YES
5062631	27734991	All authors	2	reviewed and contributed to the different draft versions, read and approved the final manuscript	reviewed and contributed to the different draft versions, read and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5062631	27734991	CAC	2	contribution to microscopic analysis, interpretation of data and manuscript drafting	contribution to microscopic analysis, interpretation of data and manuscript drafting	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft	YES
5062631	27734991	EE	2	contribution to microscopic analysis, interpretation of data and manuscript drafting	contribution to microscopic analysis, interpretation of data and manuscript drafting	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft	YES
5062631	27734991	GWLT	2	manuscript drafting	manuscript drafting	Wrote the paper	Writing - Original Draft	YES
5062631	27734991	JACHJ	2	contribution to microscopic analysis, interpretation of data and manuscript drafting	contribution to microscopic analysis, interpretation of data and manuscript drafting	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft	YES
5062631	27734991	JAO	2	contribution to microscopic analysis, interpretation of data and manuscript drafting	contribution to microscopic analysis, interpretation of data and manuscript drafting	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Original Draft	YES
5062631	27734991	KRTS	2	study design, experimental procedures, histochemical and immunohistochemical processing, microscopic analysis, data collection, figures preparation, manuscript drafting	study design, experimental procedures, histochemical and immunohistochemical processing, microscopic analysis, data collection, figures preparation, manuscript drafting	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Data curation|Formal analysis|Investigation|Methodology|Visualization|Writing - Original Draft	YES
5062631	27734991	NOB	2	manuscript drafting	manuscript drafting	Wrote the paper	Writing - Original Draft	YES
2042516	17987116	AS	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2042516	17987116	EJ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2042516	17987116	FP	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2042516	17987116	GK	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2042516	17987116	IC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
2042516	17987116	JJ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2042516	17987116	JJ	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2042516	17987116	JS	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2042516	17987116	LP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
2042516	17987116	MS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
2042516	17987116	MS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2042516	17987116	MT	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
2042516	17987116	MT	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
2042516	17987116	MT	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2042516	17987116	PM	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
2042516	17987116	RB	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2042516	17987116	RF	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2042516	17987116	RR	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2042516	17987116	RR	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2042516	17987116	RR	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2042516	17987116	WR	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
6270934	25361422	A.M.	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
6270934	25361422	A.M.	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
6270934	25361422	A.O.	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6270934	25361422	A.O.	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
6270934	25361422	A.O.	PLoS52	conceived and designed the experiments|performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
6270934	25361422	D.B.	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6270934	25361422	J.-N.M.	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
6270934	25361422	M.D.	PLoS52	conceived and designed the experiments|analyzed the data|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6270934	25361422	M.D.	PLoS52	conceived and designed the experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
6270934	25361422	M.D.	PLoS52	conceived and designed the experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270934	25361422	N.M.	PLoS52	conceived and designed the experiments|analyzed the data	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6270934	25361422	N.M.	PLoS52	conceived and designed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
6270934	25361422	T.F.	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5854654	29593768	All authors	2	listed have made a substantial, direct and intellectual contribution to the work, and approved it for publication	listed have made a substantial, direct and intellectual contribution to the work, and approved it for publication	-	-	NO
4418844	25938451	AO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Conceived and carried out the study, and had the main responsibility for the study and writing the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418844	25938451	AO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Conceived and carried out the study, and had the main responsibility for the study and writing the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4418844	25938451	AO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Conceived and carried out the study, and had the main responsibility for the study and writing the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4418844	25938451	AO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Conceived and carried out the study, and had the main responsibility for the study and writing the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418844	25938451	AO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Conceived and carried out the study, and had the main responsibility for the study and writing the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418844	25938451	AO	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Conceived and carried out the study, and had the main responsibility for the study and writing the manuscript	Conceived and carried out the study, and had the main responsibility for the study and writing the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
4418844	25938451	ELB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Realized the statistical analysis and participated in data analysis	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418844	25938451	ELB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Realized the statistical analysis and participated in data analysis	Performed the experiments	Performed the experiments	Investigation	YES
4418844	25938451	ELB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Realized the statistical analysis and participated in data analysis	Analyzed the data	Analyzed the data	Formal analysis	YES
4418844	25938451	ELB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Realized the statistical analysis and participated in data analysis	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418844	25938451	ELB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Realized the statistical analysis and participated in data analysis	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418844	25938451	ELB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Realized the statistical analysis and participated in data analysis	Realized the statistical analysis and participated in data analysis	Analyzed the data	Formal analysis	YES
4418844	25938451	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Participated in data analysis and in writing the manuscript	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418844	25938451	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Participated in data analysis and in writing the manuscript	Performed the experiments	Performed the experiments	Investigation	YES
4418844	25938451	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Participated in data analysis and in writing the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
4418844	25938451	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Participated in data analysis and in writing the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418844	25938451	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Participated in data analysis and in writing the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418844	25938451	MB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Participated in data analysis and in writing the manuscript	Participated in data analysis and in writing the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
2042517	17987117	BE	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2042517	17987117	BE	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2042517	17987117	JC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2042517	17987117	JC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2042517	17987117	JC	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2042517	17987117	MM	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2042517	17987117	MM	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6167266	30276552	New Century Excellent	2	in university	in university	-	-	NO
6167266	30276552	Sanquan Medical College	2	xinxiang medical university	xinxiang medical university	-	-	NO
6167266	30276552	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
5854660	29593760	MC	2	jointly conceived and wrote the manuscript	jointly conceived and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
5854660	29593760	SS	2	jointly conceived and wrote the manuscript	jointly conceived and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
3914523	24124051	AH	PLoS52	wrote the paper|performed the bioinformatics analysis	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3914523	24124051	AH	PLoS52	wrote the paper|performed the bioinformatics analysis	performed the bioinformatics analysis	Performed the experiments	Formal analysis|Investigation	YES
3914523	24124051	AK	PLoS52	performed the pathology	performed the pathology	Performed the experiments	Investigation	YES
3914523	24124051	AKD	PLoS52	performed the bioinformatics analysis	performed the bioinformatics analysis	Performed the experiments	Formal analysis|Investigation	YES
3914523	24124051	AL	PLoS52	performed the pathology	performed the pathology	Performed the experiments	Investigation	YES
3914523	24124051	AT	PLoS52	conceived the idea	conceived the idea	Conceived and designed the experiments	Conceptualization	YES
3914523	24124051	BK	PLoS52	conceived the idea	conceived the idea	Conceived and designed the experiments	Conceptualization	YES
3914523	24124051	CM	PLoS52	conceived the idea	conceived the idea	Conceived and designed the experiments	Conceptualization	YES
3914523	24124051	EB	PLoS52	conceived the idea|wrote the paper	conceived the idea	Conceived and designed the experiments	Conceptualization	YES
3914523	24124051	EB	PLoS52	conceived the idea|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3914523	24124051	JC	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3914523	24124051	JCC	PLoS52	conceived the idea|performed the bioinformatics analysis	conceived the idea	Conceived and designed the experiments	Conceptualization	YES
3914523	24124051	JCC	PLoS52	conceived the idea|performed the bioinformatics analysis	performed the bioinformatics analysis	Performed the experiments	Formal analysis|Investigation	YES
3914523	24124051	JL	PLoS52	performed the pathology	performed the pathology	Performed the experiments	Investigation	YES
3914523	24124051	JdG	PLoS52	performed the ngs experiments	performed the ngs experiments	Performed the experiments	Investigation	YES
3914523	24124051	LE	PLoS52	conceived the idea|performed mouse experiments	conceived the idea	Conceived and designed the experiments	Conceptualization	YES
3914523	24124051	LE	PLoS52	conceived the idea|performed mouse experiments	performed mouse experiments	Performed the experiments	Investigation	YES
3914523	24124051	ML	PLoS52	performed the bioinformatics analysis	performed the bioinformatics analysis	Performed the experiments	Formal analysis|Investigation	YES
3914523	24124051	NC-W	PLoS52	wrote the paper|performed most of the experiments of the paper|performed mouse experiments|performed the ngs experiments|performed the flow cytometric analysis	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3914523	24124051	NC-W	PLoS52	wrote the paper|performed most of the experiments of the paper|performed mouse experiments|performed the ngs experiments|performed the flow cytometric analysis	performed most of the experiments of the paper	Performed the experiments	Investigation	YES
3914523	24124051	NC-W	PLoS52	wrote the paper|performed most of the experiments of the paper|performed mouse experiments|performed the ngs experiments|performed the flow cytometric analysis	performed mouse experiments	Performed the experiments	Investigation	YES
3914523	24124051	NC-W	PLoS52	wrote the paper|performed most of the experiments of the paper|performed mouse experiments|performed the ngs experiments|performed the flow cytometric analysis	performed the ngs experiments	Performed the experiments	Investigation	YES
3914523	24124051	NC-W	PLoS52	wrote the paper|performed most of the experiments of the paper|performed mouse experiments|performed the ngs experiments|performed the flow cytometric analysis	performed the flow cytometric analysis	Performed the experiments	Investigation	YES
3914523	24124051	RH	PLoS52	performed mouse experiments	performed mouse experiments	Performed the experiments	Investigation	YES
3914523	24124051	SO	PLoS52	performed mouse experiments	performed mouse experiments	Performed the experiments	Investigation	YES
3914523	24124051	SS	PLoS52	performed the flow cytometric analysis	performed the flow cytometric analysis	Performed the experiments	Investigation	YES
3914523	24124051	TK	PLoS52	conceived the idea	conceived the idea	Conceived and designed the experiments	Conceptualization	YES
3914523	24124051	US	PLoS52	conceived the idea	conceived the idea	Conceived and designed the experiments	Conceptualization	YES
3914523	24124051	VE	PLoS52	performed mouse experiments	performed mouse experiments	Performed the experiments	Investigation	YES
3914523	24124051	YA	PLoS52	performed mouse experiments	performed mouse experiments	Performed the experiments	Investigation	YES
5859539	29558897	MC	2	designed and supervised the experiment and revised the manuscript critically	designed and supervised the experiment and revised the manuscript critically	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Review & Editing	YES
5859539	29558897	RAS	2	supervised the experiment and critically revised the manuscript	supervised the experiment and critically revised the manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
5859539	29558897	SBW	2	participated the design of the experiment, directed molecular laboratory work and data analysis, interpreted data, and critically revised the manuscript	participated the design of the experiment, directed molecular laboratory work and data analysis, interpreted data, and critically revised the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Supervision|Writing - Review & Editing	YES
5859539	29558897	SKK	2	performed the experiment and lab work, analyzed and interpreted the data, designed primers and drafted the manuscript	performed the experiment and lab work, analyzed and interpreted the data, designed primers and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5872533	29610664	BAH	2	did the literature search and wrote the manuscript together	did the literature search and wrote the manuscript together	Wrote the paper	Formal analysis|Writing - Original Draft	YES
5872533	29610664	OB	2	did the literature search and wrote the manuscript together	did the literature search and wrote the manuscript together	Wrote the paper	Formal analysis|Writing - Original Draft	YES
5062632	27734995	H.Z.	2	contributed equally to this work	contributed equally to this work	-	-	NO
5062632	27734995	HZ	2	concept and design, data acquisition and interpretation, article drafting, manuscript planning and writing	concept and design, data acquisition and interpretation, article drafting, manuscript planning and writing	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5062632	27734995	P.Y.	2	contributed equally to this work	contributed equally to this work	-	-	NO
5062632	27734995	PY	2	experimental work and study execution	experimental work and study execution	Performed the experiments	Investigation	YES
5062632	27734995	SP	2	experimental assistance	experimental assistance	-	-	NO
5062632	27734995	SZ	2	experimental work and study execution	experimental work and study execution	Performed the experiments	Investigation	YES
5062632	27734995	TG	2	experimental work and study execution	experimental work and study execution	Performed the experiments	Investigation	YES
5062632	27734995	XG	2	concept and manuscript editing	concept and manuscript editing	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Review & Editing	YES
5062632	27734995	ZZ	2	technical assistance	technical assistance	Performed the experiments	Investigation	YES
2043487	17987118	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2043487	17987118	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2043487	17987118	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2043487	17987118	AB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2043487	17987118	ES	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2043487	17987118	ES	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2043487	17987118	NT	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2043487	17987118	UR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2043487	17987118	UR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2043487	17987118	UR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418925	25938439	AQ	PLoS5	Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418925	25938439	AQ	PLoS5	Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418925	25938439	GW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418925	25938439	GW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418925	25938439	GW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418925	25938439	GW	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418925	25938439	HF	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418925	25938439	HZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418925	25938439	JL	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418925	25938439	JL	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418925	25938439	LM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4418925	25938439	LM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418925	25938439	NY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418925	25938439	NY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4418925	25938439	NY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418925	25938439	NY	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418925	25938439	XG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418925	25938439	YH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4418925	25938439	YX	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4418925	25938439	ZY	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418925	25938439	ZY	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4418925	25938439	ZY	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
6270935	25356565	Akira Fujishima	2	provided valuable discussions and advice on the manuscript	provided valuable discussions and advice on the manuscript	-	-	NO
6270935	25356565	Tadashi Machida	2	participated in study design|conducted the study	participated in study design	Conceived and designed the experiments	Methodology	YES
6270935	25356565	Tadashi Machida	2	participated in study design|conducted the study	conducted the study	Performed the experiments	Investigation	YES
6270935	25356565	Tsuyoshi Ochiai	2	participated in study design	participated in study design	Conceived and designed the experiments	Methodology	YES
6270935	25356565	Yoshitsugu Uchida	2	participated in study design|conducted the study	participated in study design	Conceived and designed the experiments	Methodology	YES
6270935	25356565	Yoshitsugu Uchida	2	participated in study design|conducted the study	conducted the study	Performed the experiments	Investigation	YES
6270935	25356565	Yuji Hayashi	2	provided valuable discussions and advice on the manuscript	provided valuable discussions and advice on the manuscript	-	-	NO
6270935	25356565	Yuko Morito	2	provided valuable discussions and advice on the manuscript	provided valuable discussions and advice on the manuscript	-	-	NO
5904302	29632268	M.W.	2	wrote the text	wrote the text	Wrote the paper	Writing - Original Draft	YES
5904302	29632268	Y.Y.	2	wrote the text|generated figures	wrote the text	Wrote the paper	Writing - Original Draft	YES
5904302	29632268	Y.Y.	2	wrote the text|generated figures	generated figures	Performed the experiments	Investigation|Visualization	YES
6167268	30276572	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6167268	30276572	JAGS	2	have designed the work|carried out the experiment|analyzed the data and contributed to the statistical analysis|wrote the manuscript and reviewed the manuscript critically	have designed the work	Conceived and designed the experiments	-	YES
6167268	30276572	JAGS	2	have designed the work|carried out the experiment|analyzed the data and contributed to the statistical analysis|wrote the manuscript and reviewed the manuscript critically	carried out the experiment	Performed the experiments	Investigation	YES
6167268	30276572	JAGS	2	have designed the work|carried out the experiment|analyzed the data and contributed to the statistical analysis|wrote the manuscript and reviewed the manuscript critically	analyzed the data and contributed to the statistical analysis	Analyzed the data	Formal analysis	YES
6167268	30276572	JAGS	2	have designed the work|carried out the experiment|analyzed the data and contributed to the statistical analysis|wrote the manuscript and reviewed the manuscript critically	wrote the manuscript and reviewed the manuscript critically	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6167268	30276572	MFL	2	have designed the work|analyzed the data and contributed to the statistical analysis|wrote the manuscript and reviewed the manuscript critically	have designed the work	Conceived and designed the experiments	-	YES
6167268	30276572	MFL	2	have designed the work|analyzed the data and contributed to the statistical analysis|wrote the manuscript and reviewed the manuscript critically	analyzed the data and contributed to the statistical analysis	Analyzed the data	Formal analysis	YES
6167268	30276572	MFL	2	have designed the work|analyzed the data and contributed to the statistical analysis|wrote the manuscript and reviewed the manuscript critically	wrote the manuscript and reviewed the manuscript critically	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6167268	30276572	MK	2	have designed the work|carried out the experiment|analyzed the data and contributed to the statistical analysis|wrote the manuscript and reviewed the manuscript critically	have designed the work	Conceived and designed the experiments	-	YES
6167268	30276572	MK	2	have designed the work|carried out the experiment|analyzed the data and contributed to the statistical analysis|wrote the manuscript and reviewed the manuscript critically	carried out the experiment	Performed the experiments	Investigation	YES
6167268	30276572	MK	2	have designed the work|carried out the experiment|analyzed the data and contributed to the statistical analysis|wrote the manuscript and reviewed the manuscript critically	analyzed the data and contributed to the statistical analysis	Analyzed the data	Formal analysis	YES
6167268	30276572	MK	2	have designed the work|carried out the experiment|analyzed the data and contributed to the statistical analysis|wrote the manuscript and reviewed the manuscript critically	wrote the manuscript and reviewed the manuscript critically	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3914524	24127423	AVF	2	conceived and performed experiments	conceived and performed experiments	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
3914524	24127423	ES	2	conceived and performed experiments	conceived and performed experiments	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
3914524	24127423	JMP	2	conceived and performed experiments	conceived and performed experiments	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
3914524	24127423	KKa	2	conceived and performed experiments	conceived and performed experiments	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
3914524	24127423	KKo	2	supervised the study, designed the experiments and wrote the manuscript|conceived and performed experiments	supervised the study, designed the experiments and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Original Draft	YES
3914524	24127423	KKo	2	supervised the study, designed the experiments and wrote the manuscript|conceived and performed experiments	conceived and performed experiments	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
3914524	24127423	MA	2	supervised the study, designed the experiments and wrote the manuscript	supervised the study, designed the experiments and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Original Draft	YES
3914524	24127423	MS	2	conceived and performed experiments	conceived and performed experiments	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
3914524	24127423	RPM	2	conceived and performed experiments	conceived and performed experiments	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
3914524	24127423	RS	2	is attending paediatrician and provided bone biopsy	is attending paediatrician and provided bone biopsy	Performed the experiments	Investigation	YES
3914524	24127423	SCK	2	conceived and performed experiments	conceived and performed experiments	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
3914524	24127423	TB	2	supervised the study, designed the experiments and wrote the manuscript|conceived and performed experiments	supervised the study, designed the experiments and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Original Draft	YES
3914524	24127423	TB	2	supervised the study, designed the experiments and wrote the manuscript|conceived and performed experiments	conceived and performed experiments	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
3914524	24127423	TO	2	conceived and performed experiments	conceived and performed experiments	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
3914524	24127423	TS	2	supervised the study, designed the experiments and wrote the manuscript	supervised the study, designed the experiments and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Supervision|Writing - Original Draft	YES
5062634	27734992	MS	2	supervision of the study	supervision of the study	-	Supervision	YES
5062634	27734992	NO	2	contributed on the acquisition of data, analysis and interpretation of the data, manuscript review, technical supports	contributed on the acquisition of data, analysis and interpretation of the data, manuscript review, technical supports	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Review & Editing	YES
5062634	27734992	YW	2	contributed on the acquisition of data, analysis and interpretation of the data, manuscript review, technical supports	contributed on the acquisition of data, analysis and interpretation of the data, manuscript review, technical supports	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Investigation|Resources|Writing - Review & Editing	YES
5855007	29593764	BF	2	performed all the phenotypic evaluation|drafted the manuscript	performed all the phenotypic evaluation	Performed the experiments	Investigation	YES
5855007	29593764	BF	2	performed all the phenotypic evaluation|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5855007	29593764	BW	2	performed analysis and interpretation of the data	performed analysis and interpretation of the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5855007	29593764	JA	2	performed all the phenotypic evaluation	performed all the phenotypic evaluation	Performed the experiments	Investigation	YES
5855007	29593764	JX	2	designed the experiment|revised the manuscript	designed the experiment	Conceived and designed the experiments	Methodology	YES
5855007	29593764	JX	2	designed the experiment|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5855007	29593764	KC	2	performed all the phenotypic evaluation	performed all the phenotypic evaluation	Performed the experiments	Investigation	YES
5855007	29593764	TZ	2	performed analysis and interpretation of the data	performed analysis and interpretation of the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5855007	29593764	WZ	2	designed the experiment|drafted the manuscript	designed the experiment	Conceived and designed the experiments	Methodology	YES
5855007	29593764	WZ	2	designed the experiment|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5855007	29593764	YC	2	performed analysis and interpretation of the data	performed analysis and interpretation of the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5855007	29593764	YZ	2	performed all the phenotypic evaluation	performed all the phenotypic evaluation	Performed the experiments	Investigation	YES
5855007	29593764	ZL	2	designed the experiment|revised the manuscript	designed the experiment	Conceived and designed the experiments	Methodology	YES
5855007	29593764	ZL	2	designed the experiment|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5891953	29662678	DWZ	2	designed the subject and performed the biological experiment and was a major contributor in writing the manuscript	designed the subject and performed the biological experiment and was a major contributor in writing the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5891953	29662678	JH	2	analyzed and interpreted the study data	analyzed and interpreted the study data	Analyzed the data	Formal analysis	YES
6270936	25521119	EO	2	performed the synthesis and characterization of the compounds	performed the synthesis and characterization of the compounds	Performed the experiments	Investigation	YES
6270936	25521119	GUE	2	supervised the was responsible for|were responsible for the parasite testing and adenosine uptake assays	supervised the was responsible for	-	Supervision	YES
6270936	25521119	GUE	2	supervised the was responsible for|were responsible for the parasite testing and adenosine uptake assays	were responsible for the parasite testing and adenosine uptake assays	Performed the experiments	Investigation	YES
6270936	25521119	HdK	2	was responsible for|were responsible for the parasite testing and adenosine uptake assays	was responsible for	-	-	NO
6270936	25521119	HdK	2	was responsible for|were responsible for the parasite testing and adenosine uptake assays	were responsible for the parasite testing and adenosine uptake assays	Performed the experiments	Investigation	YES
6270936	25521119	KLS	2	designed the synthesis	designed the synthesis	Conceived and designed the experiments	-	YES
6270936	25521119	LW	2	supervised the was responsible for|were responsible for the parasite testing and adenosine uptake assays	supervised the was responsible for	-	Supervision	YES
6270936	25521119	LW	2	supervised the was responsible for|were responsible for the parasite testing and adenosine uptake assays	were responsible for the parasite testing and adenosine uptake assays	Performed the experiments	Investigation	YES
6270936	25521119	SCZ	2	designed the synthesis|performed the synthesis and characterization of the compounds	designed the synthesis	Conceived and designed the experiments	-	YES
6270936	25521119	SCZ	2	designed the synthesis|performed the synthesis and characterization of the compounds	performed the synthesis and characterization of the compounds	Performed the experiments	Investigation	YES
5859547	29558893	AEL	2	provided biological insights and interpretations in the real data analysis and contributed to the acquisition of utilized real microbiome data	provided biological insights and interpretations in the real data analysis and contributed to the acquisition of utilized real microbiome data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
5859547	29558893	HK	2	developed the methodological ideas|implemented the methods, performed the simulations and real data analysis, and developed the software package|wrote the manuscript	developed the methodological ideas	Conceived and designed the experiments|Performed the experiments	Conceptualization|Methodology	YES
5859547	29558893	HK	2	developed the methodological ideas|implemented the methods, performed the simulations and real data analysis, and developed the software package|wrote the manuscript	implemented the methods, performed the simulations and real data analysis, and developed the software package	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Methodology|Software	YES
5859547	29558893	HK	2	developed the methodological ideas|implemented the methods, performed the simulations and real data analysis, and developed the software package|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5859547	29558893	HL	2	developed the methodological ideas|wrote the manuscript	developed the methodological ideas	Conceived and designed the experiments|Performed the experiments	Conceptualization|Methodology	YES
5859547	29558893	HL	2	developed the methodological ideas|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5859547	29558893	MJB	2	provided biological insights and interpretations in the real data analysis and contributed to the acquisition of utilized real microbiome data	provided biological insights and interpretations in the real data analysis and contributed to the acquisition of utilized real microbiome data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
2043488	17987107	DG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2043488	17987107	DG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2043488	17987107	DG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2043488	17987107	DG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2043488	17987107	DG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2043488	17987107	DS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2043488	17987107	DS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2043488	17987107	DS	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2043488	17987107	KR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2043488	17987107	KR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2043488	17987107	KR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2043488	17987107	KR	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6167272	30276499	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6167272	30276499	LLM	2	conceived this study and constructed the bioreactors	conceived this study and constructed the bioreactors	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
6167272	30276499	QH	2	contributed to analyze the data as well as results and wrote the manuscript	contributed to analyze the data as well as results and wrote the manuscript	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
6167272	30276499	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
6167272	30276499	YL	2	conceived this study and constructed the bioreactors	conceived this study and constructed the bioreactors	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
6167272	30276499	ZPL	2	conceived this study and constructed the bioreactors|supervised all the experiments and revised the manuscript	conceived this study and constructed the bioreactors	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
6167272	30276499	ZPL	2	conceived this study and constructed the bioreactors|supervised all the experiments and revised the manuscript	supervised all the experiments and revised the manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
5855100	29593763	LL	2	planned the experiments and supervised the research	planned the experiments and supervised the research	Conceived and designed the experiments	Conceptualization|Supervision	YES
5855100	29593763	MA	2	performed all the experiments on gene expression analysis|analyzed the data and drafted the manuscript	performed all the experiments on gene expression analysis	Performed the experiments	Investigation	YES
5855100	29593763	MA	2	performed all the experiments on gene expression analysis|analyzed the data and drafted the manuscript	analyzed the data and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5855100	29593763	ML	2	analyzed the data and drafted the manuscript|planned the experiments and supervised the research	analyzed the data and drafted the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5855100	29593763	ML	2	analyzed the data and drafted the manuscript|planned the experiments and supervised the research	planned the experiments and supervised the research	Conceived and designed the experiments	Conceptualization|Supervision	YES
3914525	24127415	CR	2	assessed rcan1 expression in human samples	assessed rcan1 expression in human samples	Performed the experiments	Investigation	YES
3914525	24127415	GP	2	microscopy and analysed the data obtained	microscopy and analysed the data obtained	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3914525	24127415	JMG	2	assessed rcan1 expression in human samples	assessed rcan1 expression in human samples	Performed the experiments	Investigation	YES
3914525	24127415	JMR	2	designed the study and analysed the data	designed the study and analysed the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
3914525	24127415	MRC	2	designed the study and analysed the data	designed the study and analysed the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
3914525	24127415	NMB	2	designed the study and analysed the data	designed the study and analysed the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
3914525	24127415	TM	2	provided experimental support and ideas for the project	provided experimental support and ideas for the project	Conceived and designed the experiments	Conceptualization	YES
3914525	24127415	TO	2	provided experimental support and ideas for the project	provided experimental support and ideas for the project	Conceived and designed the experiments	Conceptualization	YES
3914525	24127415	VA	2	provided experimental support and ideas for the project	provided experimental support and ideas for the project	Conceived and designed the experiments	Conceptualization	YES
3914525	24127415	VE	2	designed the study and analysed the data	designed the study and analysed the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5915715	29685975	A.K.	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5915715	29685975	A.T.	2	optimized and established rf-ms methods	optimized and established rf-ms methods	Performed the experiments	-	YES
5915715	29685975	All authors	2	contributed to writing the manuscript	contributed to writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5915715	29685975	C.J.S.	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5915715	29685975	J.B.	2	performed maldi and rf-ms experiments, data analysis and interpretation of data	performed maldi and rf-ms experiments, data analysis and interpretation of data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5062635	27734996	AR	2	experiments performing|contribution to experiment results interpretation	experiments performing	Performed the experiments	Investigation	YES
5062635	27734996	AR	2	experiments performing|contribution to experiment results interpretation	contribution to experiment results interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5062635	27734996	CG	2	contribution to experiment results interpretation	contribution to experiment results interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5062635	27734996	GF	2	research design|experiments performing|manuscript writing|research coordination, contribution to final revision of the paper	research design	Conceived and designed the experiments	-	YES
5062635	27734996	GF	2	research design|experiments performing|manuscript writing|research coordination, contribution to final revision of the paper	experiments performing	Performed the experiments	Investigation	YES
5062635	27734996	GF	2	research design|experiments performing|manuscript writing|research coordination, contribution to final revision of the paper	manuscript writing	Wrote the paper	Writing - Original Draft	YES
5062635	27734996	GF	2	research design|experiments performing|manuscript writing|research coordination, contribution to final revision of the paper	research coordination, contribution to final revision of the paper	Wrote the paper	Project administration|Writing - Review & Editing	YES
5062635	27734996	MCP	2	contribution to experiment results interpretation	contribution to experiment results interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5062635	27734996	VF	2	research coordination, contribution to final revision of the paper	research coordination, contribution to final revision of the paper	Wrote the paper	Project administration|Writing - Review & Editing	YES
5062635	27734996	VP	2	research design|experiments performing|contribution to experiment results interpretation|manuscript writing	research design	Conceived and designed the experiments	-	YES
5062635	27734996	VP	2	research design|experiments performing|contribution to experiment results interpretation|manuscript writing	experiments performing	Performed the experiments	Investigation	YES
5062635	27734996	VP	2	research design|experiments performing|contribution to experiment results interpretation|manuscript writing	contribution to experiment results interpretation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5062635	27734996	VP	2	research design|experiments performing|contribution to experiment results interpretation|manuscript writing	manuscript writing	Wrote the paper	Writing - Original Draft	YES
4677027	26693483	Jian-Hua Lu	2	contributed equally to this study	contributed equally to this study	-	-	NO
4677027	26693483	Yi-Qian Liu	2	contributed equally to this study	contributed equally to this study	-	-	NO
6270937	24983860	Huiping Chen	2	gave some assistance on experiment	gave some assistance on experiment	Performed the experiments	Investigation	YES
6270937	24983860	Lianzhu Lin	2	were instructors and suggested the idea of this work	were instructors and suggested the idea of this work	Conceived and designed the experiments	Conceptualization|Supervision	YES
6270937	24983860	Mengying Feng	2	checked the grammar and spell of this paper	checked the grammar and spell of this paper	Wrote the paper	Writing - Review & Editing	YES
6270937	24983860	Mingzhu Zhuang	2	checked the grammar and spell of this paper	checked the grammar and spell of this paper	Wrote the paper	Writing - Review & Editing	YES
6270937	24983860	Mouming Zhao	2	were instructors and suggested the idea of this work	were instructors and suggested the idea of this work	Conceived and designed the experiments	Conceptualization|Supervision	YES
6270937	24983860	Tiantian Zhao	2	gave some assistance on experiment	gave some assistance on experiment	Performed the experiments	Investigation	YES
6270937	24983860	Yi Dong	2	wrote this paper and acted all experiments	wrote this paper and acted all experiments	Wrote the paper	Writing - Original Draft	YES
2043489	17987120	AZ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2043489	17987120	DC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
2043489	17987120	DC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2043489	17987120	EL	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
2043489	17987120	EL	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2043489	17987120	LM	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
2043489	17987120	LM	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2043489	17987120	MC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
2043489	17987120	ML	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
2043489	17987120	MP	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2043489	17987120	PK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2043489	17987120	PK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2043489	17987120	PK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2043489	17987120	PK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2043489	17987120	PK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2043489	17987120	PR	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
2043489	17987120	RG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
2043489	17987120	RG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2043489	17987120	RK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
2043489	17987120	SR	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2043489	17987120	TC	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
2043489	17987120	TC	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2043489	17987120	WD	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5859760	29554873	CB	2	are at the origin of the conception of the program and defined the experimental design|supervised the phenotyping	are at the origin of the conception of the program and defined the experimental design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5859760	29554873	CB	2	are at the origin of the conception of the program and defined the experimental design|supervised the phenotyping	supervised the phenotyping	Performed the experiments	Investigation|Supervision	YES
5859760	29554873	CHA	2	supervised the under the|contributed to the choice of tools and methodologies used for gwas analysis	supervised the under the	-	Supervision	YES
5859760	29554873	CHA	2	supervised the under the|contributed to the choice of tools and methodologies used for gwas analysis	contributed to the choice of tools and methodologies used for gwas analysis	Performed the experiments|Contributed reagents/materials/analysis tools	Methodology|Resources	YES
5859760	29554873	EG	2	designed and tested the oligonucleotide primers used for quantitative rt-qpcr analysis|performed rna extraction	designed and tested the oligonucleotide primers used for quantitative rt-qpcr analysis	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5859760	29554873	EG	2	designed and tested the oligonucleotide primers used for quantitative rt-qpcr analysis|performed rna extraction	performed rna extraction	Performed the experiments	Investigation	YES
5859760	29554873	ELBD	2	are at the origin of the conception of the program and defined the experimental design|supervised the phenotyping|supervised the under the|supervised the drafted the first version of the manuscript under the	are at the origin of the conception of the program and defined the experimental design	Conceived and designed the experiments	Conceptualization|Methodology	YES
5859760	29554873	ELBD	2	are at the origin of the conception of the program and defined the experimental design|supervised the phenotyping|supervised the under the|supervised the drafted the first version of the manuscript under the	supervised the phenotyping	Performed the experiments	Investigation|Supervision	YES
5859760	29554873	ELBD	2	are at the origin of the conception of the program and defined the experimental design|supervised the phenotyping|supervised the under the|supervised the drafted the first version of the manuscript under the	supervised the under the	-	Supervision	YES
5859760	29554873	ELBD	2	are at the origin of the conception of the program and defined the experimental design|supervised the phenotyping|supervised the under the|supervised the drafted the first version of the manuscript under the	supervised the drafted the first version of the manuscript under the	Wrote the paper	Supervision|Writing - Original Draft	YES
5859760	29554873	EP	2	designed and tested the oligonucleotide primers used for quantitative rt-qpcr analysis|drafted the first version of the manuscript under the	designed and tested the oligonucleotide primers used for quantitative rt-qpcr analysis	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5859760	29554873	EP	2	designed and tested the oligonucleotide primers used for quantitative rt-qpcr analysis|drafted the first version of the manuscript under the	drafted the first version of the manuscript under the	Wrote the paper	Writing - Original Draft	YES
5859760	29554873	QTL	2	eqtl detection analyses, under the	eqtl detection analyses, under the	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5859760	29554873	SAB	2	designed and tested the oligonucleotide primers used for quantitative rt-qpcr analysis|performed rna extraction	designed and tested the oligonucleotide primers used for quantitative rt-qpcr analysis	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5859760	29554873	SAB	2	designed and tested the oligonucleotide primers used for quantitative rt-qpcr analysis|performed rna extraction	performed rna extraction	Performed the experiments	Investigation	YES
5859760	29554873	SB	2	supervised the under the|contributed to the choice of tools and methodologies used for gwas analysis	supervised the under the	-	Supervision	YES
5859760	29554873	SB	2	supervised the under the|contributed to the choice of tools and methodologies used for gwas analysis	contributed to the choice of tools and methodologies used for gwas analysis	Performed the experiments|Contributed reagents/materials/analysis tools	Methodology|Resources	YES
5859760	29554873	YJ	2	are at the origin of the conception of the program and defined the experimental design	are at the origin of the conception of the program and defined the experimental design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6170513	30284112	The author	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6170513	30284112	YI	2	carried out the experimental studies and wrote the manuscript text	carried out the experimental studies and wrote the manuscript text	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5855183	29593766	J-KK	2	wrote the manuscript and prepared the figures	wrote the manuscript and prepared the figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5855183	29593766	JSS	2	performed experiments|wrote the manuscript and prepared the figures	performed experiments	Performed the experiments	Investigation	YES
5855183	29593766	JSS	2	performed experiments|wrote the manuscript and prepared the figures	wrote the manuscript and prepared the figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5855183	29593766	NO	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5855183	29593766	PJC	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5855183	29593766	YDC	2	wrote the manuscript and prepared the figures	wrote the manuscript and prepared the figures	Wrote the paper	Visualization|Writing - Original Draft	YES
5855183	29593766	YSK	2	performed field experiments and analyzed yield components in field conditions	performed field experiments and analyzed yield components in field conditions	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5899386	29686878	AA	2	contributed to the statistical analysis and to the interpretation of the data, critical revision of the manuscript, and final approval of the version to be published	contributed to the statistical analysis and to the interpretation of the data, critical revision of the manuscript, and final approval of the version to be published	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5899386	29686878	All authors	2	have participated in the data collection, and they have read and approved the final manuscript	have participated in the data collection, and they have read and approved the final manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
5899386	29686878	CS	2	have revised the text and made methodological contributions, and they have given the experts point of view	have revised the text and made methodological contributions, and they have given the experts point of view	Performed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5899386	29686878	FR	2	are the guarantor of the paper and takes responsibility for the integrity of the work as a whole, from inception to the published article	are the guarantor of the paper and takes responsibility for the integrity of the work as a whole, from inception to the published article	-	-	NO
5899386	29686878	JM	2	have revised the text and made methodological contributions, and they have given the experts point of view	have revised the text and made methodological contributions, and they have given the experts point of view	Performed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5899386	29686878	RO	2	are the guarantor of the paper and takes responsibility for the integrity of the work as a whole, from inception to the published article	are the guarantor of the paper and takes responsibility for the integrity of the work as a whole, from inception to the published article	-	-	NO
3914526	24142880	ADR	2	analysed data	analysed data	Analyzed the data	Formal analysis	YES
3914526	24142880	AK	2	analysed data	analysed data	Analyzed the data	Formal analysis	YES
3914526	24142880	AL	2	provided materials and participated in data analyses	provided materials and participated in data analyses	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
3914526	24142880	AME	2	provided materials, participated in data analysis, revised the article	provided materials, participated in data analysis, revised the article	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
3914526	24142880	CL	2	performed experiments and analysed data	performed experiments and analysed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3914526	24142880	CT	2	designed experiments, analysed data, wrote the article	designed experiments, analysed data, wrote the article	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3914526	24142880	EC	2	analysed data	analysed data	Analyzed the data	Formal analysis	YES
3914526	24142880	FR	2	provided materials, participated in data analysis, revised the article	provided materials, participated in data analysis, revised the article	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
3914526	24142880	GS	2	performed experiments and analysed data	performed experiments and analysed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3914526	24142880	IBP	2	designed experiments, analysed data, wrote the article	designed experiments, analysed data, wrote the article	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3914526	24142880	LT	2	performed experiments and analysed data	performed experiments and analysed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3914526	24142880	MEB	2	designed experiments, analysed data, wrote the article|performed experiments and analysed data	designed experiments, analysed data, wrote the article	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
3914526	24142880	MEB	2	designed experiments, analysed data, wrote the article|performed experiments and analysed data	performed experiments and analysed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3914526	24142880	OL	2	provided materials, participated in data analysis, revised the article	provided materials, participated in data analysis, revised the article	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
3914526	24142880	SK	2	performed experiments and analysed data	performed experiments and analysed data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3914526	24142880	TL	2	provided materials and participated in data analyses	provided materials and participated in data analyses	Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Resources	YES
3914526	24142880	YA	2	provided materials, participated in data analysis, revised the article	provided materials, participated in data analysis, revised the article	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Review & Editing	YES
5915717	29685977	M.J.K.	2	assisted with editing	assisted with editing	Wrote the paper	Writing - Review & Editing	YES
4418965	25923521	DG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418965	25923521	DG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418965	25923521	DG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418965	25923521	MG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418965	25923521	MG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418965	25923521	MG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418965	25923521	MR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418965	25923521	MR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418965	25923521	MR	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418965	25923521	NB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418965	25923521	NB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418965	25923521	NB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418965	25923521	PK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418965	25923521	PK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418965	25923521	PK	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418965	25923521	RB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418965	25923521	RB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418965	25923521	RB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418965	25923521	TB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418965	25923521	TB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418965	25923521	TB	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418965	25923521	TC-S	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418965	25923521	TC-S	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418965	25923521	TC-S	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4418965	25923521	TO	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4418965	25923521	TO	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4418965	25923521	TO	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270938	25068781	IP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6270938	25068781	IP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
6270938	25068781	IP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
6270938	25068781	PS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6270938	25068781	PS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
6270938	25068781	PS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
6270938	25068781	PS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270938	25068781	ZD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6270938	25068781	ZD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
6270938	25068781	ZD	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
6270938	25068781	ZT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6270938	25068781	ZT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
6270938	25068781	ZT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
6270938	25068781	ZT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2043490	17987112	AC	PLoS5	Conceived and designed the experiments|Wrote large parts of the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2043490	17987112	AC	PLoS5	Conceived and designed the experiments|Wrote large parts of the paper	Wrote large parts of the paper	Wrote the paper	Writing - Original Draft	YES
2043490	17987112	ACJ	PLoS5	Contributed to paper writing	Contributed to paper writing	Wrote the paper	-	YES
2043490	17987112	CY	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote large parts of the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2043490	17987112	CY	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote large parts of the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2043490	17987112	CY	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote large parts of the paper	Wrote large parts of the paper	Wrote the paper	Writing - Original Draft	YES
2043490	17987112	FAB	PLoS5	Contributed to paper writing	Contributed to paper writing	Wrote the paper	-	YES
2043490	17987112	JSP	PLoS5	Contributed to project planning	Contributed to project planning	Conceived and designed the experiments	Methodology	YES
2043490	17987112	MB	PLoS5	Contributed to project planning	Contributed to project planning	Conceived and designed the experiments	Methodology	YES
2043490	17987112	NC	PLoS5	Contributed to project planning	Contributed to project planning	Conceived and designed the experiments	Methodology	YES
2043490	17987112	PWB	PLoS5	Contributed data and tools|Contributed to paper writing	Contributed data and tools	Contributed reagents/materials/analysis tools	Resources	YES
2043490	17987112	PWB	PLoS5	Contributed data and tools|Contributed to paper writing	Contributed to paper writing	Wrote the paper	-	YES
2043490	17987112	RJW	PLoS5	Contributed to paper writing	Contributed to paper writing	Wrote the paper	-	YES
2043490	17987112	TS	PLoS5	Contributed data and tools|Contributed to paper writing	Contributed data and tools	Contributed reagents/materials/analysis tools	Resources	YES
2043490	17987112	TS	PLoS5	Contributed data and tools|Contributed to paper writing	Contributed to paper writing	Wrote the paper	-	YES
5855324	29593756	AG-C	2	conducted the experiments|wrote the manuscript	conducted the experiments	Performed the experiments	Investigation	YES
5855324	29593756	AG-C	2	conducted the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5855324	29593756	AM-S	2	analyzed the data, interpreted the results, conceived and designed the experiments, and contributed materials, equipment, and analysis tools|conducted the experiments|wrote the manuscript	analyzed the data, interpreted the results, conceived and designed the experiments, and contributed materials, equipment, and analysis tools	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Methodology|Resources	YES
5855324	29593756	AM-S	2	analyzed the data, interpreted the results, conceived and designed the experiments, and contributed materials, equipment, and analysis tools|conducted the experiments|wrote the manuscript	conducted the experiments	Performed the experiments	Investigation	YES
5855324	29593756	AM-S	2	analyzed the data, interpreted the results, conceived and designed the experiments, and contributed materials, equipment, and analysis tools|conducted the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5855324	29593756	All authors	2	reviewed the manuscript and approved the final version	reviewed the manuscript and approved the final version	Wrote the paper	Writing - Review & Editing	YES
5855324	29593756	LM-R	2	analyzed the data, interpreted the results, conceived and designed the experiments, and contributed materials, equipment, and analysis tools|wrote the manuscript	analyzed the data, interpreted the results, conceived and designed the experiments, and contributed materials, equipment, and analysis tools	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceptualization|Formal analysis|Methodology|Resources	YES
5855324	29593756	LM-R	2	analyzed the data, interpreted the results, conceived and designed the experiments, and contributed materials, equipment, and analysis tools|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5855324	29593756	PM-F	2	conducted the experiments|wrote the manuscript	conducted the experiments	Performed the experiments	Investigation	YES
5855324	29593756	PM-F	2	conducted the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5855324	29593756	SC-S	2	conducted the experiments|wrote the manuscript	conducted the experiments	Performed the experiments	Investigation	YES
5855324	29593756	SC-S	2	conducted the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5855324	29593756	SG-F	2	conducted the experiments	conducted the experiments	Performed the experiments	Investigation	YES
5855324	29593756	SR	2	conducted the experiments	conducted the experiments	Performed the experiments	Investigation	YES
5859761	29554865	H-YC	2	planned and designed the research	planned and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5859761	29554865	JL	2	planned and designed the research|performed experiments|analyzed data|wrote the manuscript	planned and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5859761	29554865	JL	2	planned and designed the research|performed experiments|analyzed data|wrote the manuscript	performed experiments	Performed the experiments	Investigation	YES
5859761	29554865	JL	2	planned and designed the research|performed experiments|analyzed data|wrote the manuscript	analyzed data	Analyzed the data	Formal analysis	YES
5859761	29554865	JL	2	planned and designed the research|performed experiments|analyzed data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5859761	29554865	LR	2	planned and designed the research|performed experiments	planned and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5859761	29554865	LR	2	planned and designed the research|performed experiments	performed experiments	Performed the experiments	Investigation	YES
5859761	29554865	LZ	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5859761	29554865	M-MJ	2	planned and designed the research	planned and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5859761	29554865	Y-JH	2	performed experiments|wrote the manuscript	performed experiments	Performed the experiments	Investigation	YES
5859761	29554865	Y-JH	2	performed experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5859761	29554865	YL	2	planned and designed the research	planned and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5062639	27734993	ADG	2	project design, manuscript writing|statistical analysis	project design, manuscript writing	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5062639	27734993	ADG	2	project design, manuscript writing|statistical analysis	statistical analysis	Analyzed the data	Formal analysis	YES
5062639	27734993	All authors	2	contributed to the different draft versions of the manuscript and approved the final manuscript	contributed to the different draft versions of the manuscript and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5062639	27734993	MCV	2	subjects providing, clinical evaluation performing	subjects providing, clinical evaluation performing	Performed the experiments	Investigation	YES
5062639	27734993	MDG	2	subjects providing, clinical evaluation performing	subjects providing, clinical evaluation performing	Performed the experiments	Investigation	YES
5062639	27734993	MEA	2	experimental procedures and microscopic analyses	experimental procedures and microscopic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5062639	27734993	PT	2	experimental procedures and microscopic analyses	experimental procedures and microscopic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5062639	27734993	SCM	2	project design, manuscript writing	project design, manuscript writing	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
6170517	30284053	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6170517	30284053	BX	PLoS52	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
6170517	30284053	FX	PLoS52	designed the study|conducted the experiment|analyzed the data|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
6170517	30284053	FX	PLoS52	designed the study|conducted the experiment|analyzed the data|wrote the manuscript	conducted the experiment	Performed the experiments	Investigation	YES
6170517	30284053	FX	PLoS52	designed the study|conducted the experiment|analyzed the data|wrote the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
6170517	30284053	FX	PLoS52	designed the study|conducted the experiment|analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6170517	30284053	Fuyu Sun	PLoS52	conducted the experiment	conducted the experiment	Performed the experiments	Investigation	YES
6170517	30284053	LJ	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
6170517	30284053	XN	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
6170517	30284053	XP	PLoS52	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
6170517	30284053	YG	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5915718	29685978	D.J.H.	2	contributed to specific content of the review by preparing the main text|prepared the tables	contributed to specific content of the review by preparing the main text	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5915718	29685978	D.J.H.	2	contributed to specific content of the review by preparing the main text|prepared the tables	prepared the tables	-	-	NO
5915718	29685978	M.B.	2	contributed to specific content of the review by preparing the main text	contributed to specific content of the review by preparing the main text	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5915718	29685978	M.E.	2	contributed to specific content of the review by preparing the main text	contributed to specific content of the review by preparing the main text	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5918845	29721320	All authors	2	critically reviewed the manuscript	critically reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
5918845	29721320	HM	2	collected the data	collected the data	Performed the experiments	Investigation	YES
5918845	29721320	KF	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5918845	29721320	KL	2	collected the data	collected the data	Performed the experiments	Investigation	YES
5918845	29721320	KM	2	designed the study|performed the analyses|drafted the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5918845	29721320	KM	2	designed the study|performed the analyses|drafted the manuscript	performed the analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5918845	29721320	KM	2	designed the study|performed the analyses|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5918845	29721320	KT	2	performed the analyses	performed the analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5918845	29721320	MNa	2	designed the study	designed the study	Conceived and designed the experiments	Methodology	YES
5918845	29721320	MNi	2	designed the study|performed the analyses|collected the data|drafted the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5918845	29721320	MNi	2	designed the study|performed the analyses|collected the data|drafted the manuscript	performed the analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5918845	29721320	MNi	2	designed the study|performed the analyses|collected the data|drafted the manuscript	collected the data	Performed the experiments	Investigation	YES
5918845	29721320	MNi	2	designed the study|performed the analyses|collected the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5918845	29721320	NM	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5918845	29721320	SM	2	designed the study|performed the analyses|drafted the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5918845	29721320	SM	2	designed the study|performed the analyses|drafted the manuscript	performed the analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5918845	29721320	SM	2	designed the study|performed the analyses|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5918845	29721320	TO	2	designed the study|drafted the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
5918845	29721320	TO	2	designed the study|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
6270940	25225722	Caroline T. Weber	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
6270940	25225722	Edson Foletto	PLoS52	analyzed the data and wrote the paper	analyzed the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6270940	25225722	Marcio Mazutti	PLoS52	analyzed the data and wrote the paper	analyzed the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6270940	25225722	Raquel Kuhn	PLoS52	analyzed the data and wrote the paper	analyzed the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6270940	25225722	Rodrigo Klaic	PLoS52	analyzed the data and wrote the paper	analyzed the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6270940	25225722	Sergio Jahn	PLoS52	analyzed the data and wrote the paper	analyzed the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6270940	25225722	Tais B. Garlet	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
2043491	17987121	CL	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2043491	17987121	CL	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2043491	17987121	CL	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2043491	17987121	CZ	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2043491	17987121	CZ	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2043491	17987121	DW	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2043491	17987121	JZ	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2043491	17987121	KZ	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2043491	17987121	LZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
2043491	17987121	PZ	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
2043491	17987121	PZ	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2043491	17987121	QL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2043491	17987121	SJ	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2043491	17987121	XC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
2043491	17987121	XJ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
2043491	17987121	XL	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2043491	17987121	XL	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2043491	17987121	XQ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
2043491	17987121	YX	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2043491	17987121	YX	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2043491	17987121	YZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2043491	17987121	YZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2043491	17987121	YZ	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4420245	25942563	DDF	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4420245	25942563	FYZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4420245	25942563	JZH	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4420245	25942563	LL	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4420245	25942563	QMC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4420245	25942563	SJY	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4420245	25942563	SJY	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4420245	25942563	SWL	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4420245	25942563	WL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4420245	25942563	XPP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4420245	25942563	XTH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4420245	25942563	Y. Li	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4420245	25942563	Y. Li	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4420245	25942563	Y. Li	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4420245	25942563	Y. Liu	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4420245	25942563	Y. Liu	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4420245	25942563	YHH	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4420245	25942563	ZQL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4420245	25942563	ZQL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4420245	25942563	ZQL	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4677160	26697489	Quan Li	2	equally contributed to this project	equally contributed to this project	-	-	NO
4677160	26697489	Yanzhen Wang	2	equally contributed to this project	equally contributed to this project	-	-	NO
3914529	24136784	CHL	PLoS52	conceived and designed the experiments|analysed the data	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
3914529	24136784	CHL	PLoS52	conceived and designed the experiments|analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
3914529	24136784	HA	PLoS52	conceived and designed the experiments|analysed the data|wrote and reviewed the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
3914529	24136784	HA	PLoS52	conceived and designed the experiments|analysed the data|wrote and reviewed the paper	analysed the data	Analyzed the data	Formal analysis	YES
3914529	24136784	HA	PLoS52	conceived and designed the experiments|analysed the data|wrote and reviewed the paper	wrote and reviewed the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3914529	24136784	IJ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
3914529	24136784	JAH	PLoS52	conceived and designed the experiments|analysed the data|wrote and reviewed the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
3914529	24136784	JAH	PLoS52	conceived and designed the experiments|analysed the data|wrote and reviewed the paper	analysed the data	Analyzed the data	Formal analysis	YES
3914529	24136784	JAH	PLoS52	conceived and designed the experiments|analysed the data|wrote and reviewed the paper	wrote and reviewed the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3914529	24136784	LP	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
3914529	24136784	MG	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
3914529	24136784	MRA	PLoS52	performed the experiments|analysed the data	performed the experiments	Performed the experiments	Investigation	YES
3914529	24136784	MRA	PLoS52	performed the experiments|analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
3914529	24136784	MS	PLoS52	conceived and designed the experiments|performed the experiments|analysed the data|wrote and reviewed the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
3914529	24136784	MS	PLoS52	conceived and designed the experiments|performed the experiments|analysed the data|wrote and reviewed the paper	performed the experiments	Performed the experiments	Investigation	YES
3914529	24136784	MS	PLoS52	conceived and designed the experiments|performed the experiments|analysed the data|wrote and reviewed the paper	analysed the data	Analyzed the data	Formal analysis	YES
3914529	24136784	MS	PLoS52	conceived and designed the experiments|performed the experiments|analysed the data|wrote and reviewed the paper	wrote and reviewed the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3914529	24136784	SGB	PLoS52	performed the experiments|analysed the data|wrote and reviewed the paper	performed the experiments	Performed the experiments	Investigation	YES
3914529	24136784	SGB	PLoS52	performed the experiments|analysed the data|wrote and reviewed the paper	analysed the data	Analyzed the data	Formal analysis	YES
3914529	24136784	SGB	PLoS52	performed the experiments|analysed the data|wrote and reviewed the paper	wrote and reviewed the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3914529	24136784	SH	PLoS52	conceived and designed the experiments|analysed the data|wrote and reviewed the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
3914529	24136784	SH	PLoS52	conceived and designed the experiments|analysed the data|wrote and reviewed the paper	analysed the data	Analyzed the data	Formal analysis	YES
3914529	24136784	SH	PLoS52	conceived and designed the experiments|analysed the data|wrote and reviewed the paper	wrote and reviewed the paper	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3914529	24136784	TMA	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
3914529	24136784	TP	PLoS52	performed the experiments|analysed the data	performed the experiments	Performed the experiments	Investigation	YES
3914529	24136784	TP	PLoS52	performed the experiments|analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
5861650	29562890	AB	2	conceived, conducted, and wrote the t-cell experimental work	conceived, conducted, and wrote the t-cell experimental work	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
5861650	29562890	All authors	2	were involved in drafting the manuscript, have given final approval for publication, and agreed to be accountable for all aspects of the work	were involved in drafting the manuscript, have given final approval for publication, and agreed to be accountable for all aspects of the work	Wrote the paper	Writing - Original Draft	YES
5861650	29562890	CW	2	conceived of the method and analysis|were primary authors for the manuscript	conceived of the method and analysis	Conceived and designed the experiments|Performed the experiments	Conceptualization	YES
5861650	29562890	CW	2	conceived of the method and analysis|were primary authors for the manuscript	were primary authors for the manuscript	Wrote the paper	Writing - Original Draft	YES
5861650	29562890	DC	2	conceived of the method and analysis	conceived of the method and analysis	Conceived and designed the experiments|Performed the experiments	Conceptualization	YES
5861650	29562890	EM	2	conceived of the method and analysis|were primary authors for the manuscript	conceived of the method and analysis	Conceived and designed the experiments|Performed the experiments	Conceptualization	YES
5861650	29562890	EM	2	conceived of the method and analysis|were primary authors for the manuscript	were primary authors for the manuscript	Wrote the paper	Writing - Original Draft	YES
5861650	29562890	GG	2	conceived of the method and analysis|were primary authors for the manuscript	conceived of the method and analysis	Conceived and designed the experiments|Performed the experiments	Conceptualization	YES
5861650	29562890	GG	2	conceived of the method and analysis|were primary authors for the manuscript	were primary authors for the manuscript	Wrote the paper	Writing - Original Draft	YES
5861650	29562890	HA	2	conceived, conducted, and wrote the t-cell experimental work	conceived, conducted, and wrote the t-cell experimental work	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
5861650	29562890	HJ	2	conducted bioinformatics, statistical, and computational analysis|additionally provided tn5 biochemistry agents	conducted bioinformatics, statistical, and computational analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5861650	29562890	HJ	2	conducted bioinformatics, statistical, and computational analysis|additionally provided tn5 biochemistry agents	additionally provided tn5 biochemistry agents	Performed the experiments	Investigation	YES
5861650	29562890	LB	2	conducted bioinformatics, statistical, and computational analysis	conducted bioinformatics, statistical, and computational analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5861650	29562890	MM	2	conceived and conducted the cep290 gene editing experiments	conceived and conducted the cep290 gene editing experiments	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Review & Editing	YES
5861650	29562890	MS	2	conceived and conducted the cep290 gene editing experiments	conceived and conducted the cep290 gene editing experiments	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Review & Editing	YES
5861650	29562890	SG	2	conceived and conducted the cep290 gene editing experiments	conceived and conducted the cep290 gene editing experiments	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Review & Editing	YES
5861650	29562890	TW	2	conducted bioinformatics, statistical, and computational analysis	conducted bioinformatics, statistical, and computational analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5861650	29562890	UDiT	2	amp-seq data	amp-seq data	-	-	NO
5861650	29562890	VM	2	conceived of the method and analysis	conceived of the method and analysis	Conceived and designed the experiments|Performed the experiments	Conceptualization	YES
5930426	29744108	AH	2	proof-read the manuscript and provided expertise in fatigue	proof-read the manuscript and provided expertise in fatigue	-	-	NO
5930426	29744108	BS	2	gave methodological and statistical advice on the study design, enrollment, and data analysis	gave methodological and statistical advice on the study design, enrollment, and data analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5930426	29744108	GBW	2	realized the statistical analyses and wrote the manuscript	realized the statistical analyses and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5930426	29744108	JR	2	supervised the data collection	supervised the data collection	Performed the experiments	Investigation|Supervision	YES
5930426	29744108	KP	2	supervised the data collection	supervised the data collection	Performed the experiments	Investigation|Supervision	YES
5930426	29744108	KW	2	gave methodological and statistical advice on the study design, enrollment, and data analysis	gave methodological and statistical advice on the study design, enrollment, and data analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
6170518	30284060	All authors	2	discussed the results and contribute to the final manuscript|read and approved the final manuscript	discussed the results and contribute to the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6170518	30284060	All authors	2	discussed the results and contribute to the final manuscript|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6170518	30284060	GW	2	completed the experiment and data analysis	completed the experiment and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6170518	30284060	Guo Qian	2	for her linguistic assistance during the preparation of this manuscript, and the anonymous reviewers for their helpful comments regarding the manuscript	for her linguistic assistance during the preparation of this manuscript, and the anonymous reviewers for their helpful comments regarding the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
6170518	30284060	JX	2	conceived the original idea and supervise the project	conceived the original idea and supervise the project	Conceived and designed the experiments	Conceptualization|Supervision	YES
6170518	30284060	LL	2	completed the experiment and data analysis|wrote the draft of the manuscript	completed the experiment and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6170518	30284060	LL	2	completed the experiment and data analysis|wrote the draft of the manuscript	wrote the draft of the manuscript	Wrote the paper	Writing - Original Draft	YES
6170518	30284060	MY	2	completed the experiment and data analysis	completed the experiment and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6170518	30284060	Microorganism Application	2	at tsinghua university is appreciated	at tsinghua university is appreciated	-	-	NO
5855893	29593765	LA-ICPMS	2	studies and reading of the manuscript	studies and reading of the manuscript	-	-	NO
5855893	29593765	MA-XRF	2	studies and reading of the manuscript	studies and reading of the manuscript	-	-	NO
5134679	28076935	CA	2	manuscript critical revision and approval	manuscript critical revision and approval	Wrote the paper	Writing - Review & Editing	YES
5134679	28076935	CL	2	manuscript critical revision and approval	manuscript critical revision and approval	Wrote the paper	Writing - Review & Editing	YES
5134679	28076935	DM	2	study design, acquisition, analysis and interpretation of data, manuscript drafting critical revision and approval	study design, acquisition, analysis and interpretation of data, manuscript drafting critical revision and approval	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
5134679	28076935	GT	2	study design, acquisition, analysis and interpretation of data, manuscript drafting	study design, acquisition, analysis and interpretation of data, manuscript drafting	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5134679	28076935	MC	2	manuscript critical revision and approval	manuscript critical revision and approval	Wrote the paper	Writing - Review & Editing	YES
5134679	28076935	SRG	2	manuscript critical revision and approval	manuscript critical revision and approval	Wrote the paper	Writing - Review & Editing	YES
2043492	17987114	GM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2043492	17987114	GM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
2043492	17987114	GM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2043492	17987114	IB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2043492	17987114	IB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2043492	17987114	IB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2043492	17987114	IB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2043492	17987114	PL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2043492	17987114	PL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2043492	17987114	PL	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270941	24858273	B.-X.S.	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
6270941	24858273	H.-L.G.	PLoS52	conceived and designed the experiments|performed the experiments|wrote the paper and contributed to the data analysis and interpretation	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6270941	24858273	H.-L.G.	PLoS52	conceived and designed the experiments|performed the experiments|wrote the paper and contributed to the data analysis and interpretation	performed the experiments	Performed the experiments	Investigation	YES
6270941	24858273	H.-L.G.	PLoS52	conceived and designed the experiments|performed the experiments|wrote the paper and contributed to the data analysis and interpretation	wrote the paper and contributed to the data analysis and interpretation	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6270941	24858273	S.-S.L.	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6270941	24858273	X.-W.Z.	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
4677161	26697497	Hao Wu	2	are with equal contributions	are with equal contributions	-	-	NO
4677161	26697497	Jonathan C. Sedeyn	2	are with equal contributions	are with equal contributions	-	-	NO
5861657	29558886	CKL	2	performed in vitro infection	performed in vitro infection	Performed the experiments	Investigation	YES
5861657	29558886	FK	2	wrote the manuscript and analyzed the data|participated in primers design and qpcr analysis	wrote the manuscript and analyzed the data	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5861657	29558886	FK	2	wrote the manuscript and analyzed the data|participated in primers design and qpcr analysis	participated in primers design and qpcr analysis	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5861657	29558886	JFG	2	conceived and designed the project and prepared materials for the study	conceived and designed the project and prepared materials for the study	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
5861657	29558886	QYZ	2	conceived and designed the project and prepared materials for the study|wrote the manuscript and analyzed the data	conceived and designed the project and prepared materials for the study	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation|Methodology	YES
5861657	29558886	QYZ	2	conceived and designed the project and prepared materials for the study|wrote the manuscript and analyzed the data	wrote the manuscript and analyzed the data	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5861657	29558886	TL	2	performed sample collection and rna isolation	performed sample collection and rna isolation	Performed the experiments	Investigation	YES
5861657	29558886	ZHW	2	participated in primers design and qpcr analysis	participated in primers design and qpcr analysis	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5861657	29558886	ZYC	2	performed sample collection and rna isolation	performed sample collection and rna isolation	Performed the experiments	Investigation	YES
5134680	28076930	All the authors	2	substantially contributed to the work and have approved the final version of the paper	substantially contributed to the work and have approved the final version of the paper	-	-	NO
5134680	28076930	CB	2	fascia collecting from the volunteers	fascia collecting from the volunteers	-	-	NO
5134680	28076930	CF	2	manuscript drafting, isolation, culture cells and rt pcr	manuscript drafting, isolation, culture cells and rt pcr	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5134680	28076930	CS	2	participation in manuscript writing and editing, and in work coordination	participation in manuscript writing and editing, and in work coordination	Wrote the paper	Project administration|Writing - Original Draft|Writing - Review & Editing	YES
5134680	28076930	LP	2	responsible for immunostaining	responsible for immunostaining	Performed the experiments	Investigation	YES
5134680	28076930	MMS	2	contribution to cells isolating and immunostaining	contribution to cells isolating and immunostaining	Performed the experiments	Investigation	YES
5134680	28076930	RDC	2	participation in manuscript writing and editing, and in work coordination	participation in manuscript writing and editing, and in work coordination	Wrote the paper	Project administration|Writing - Original Draft|Writing - Review & Editing	YES
4420246	25942440	CJK	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4420246	25942440	JSL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4420246	25942440	JSL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4420246	25942440	JSL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4420246	25942440	JSL	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4420246	25942440	JYM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4420246	25942440	JYM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4420246	25942440	MEP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4420246	25942440	MRT	PLoS5	Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4420246	25942440	MRT	PLoS5	Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4420246	25942440	MYEC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4420246	25942440	MYEC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4420246	25942440	MYEC	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4420246	25942440	PW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4420246	25942440	THK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4420246	25942440	WKC	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5857585	29593754	D-DM	2	assisted in some experiments and helped analyze the data	assisted in some experiments and helped analyze the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5857585	29593754	J-LQ	2	provided tools and reagents and made helpful discussions	provided tools and reagents and made helpful discussions	Contributed reagents/materials/analysis tools	Resources	YES
5857585	29593754	LY	2	provided tools and reagents and made helpful discussions	provided tools and reagents and made helpful discussions	Contributed reagents/materials/analysis tools	Resources	YES
5857585	29593754	Q-LT	2	assisted in some experiments and helped analyze the data	assisted in some experiments and helped analyze the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5857585	29593754	R-JT	2	designed and conducted most of the experiments, interpreted the results, and wrote the draft of the manuscript	designed and conducted most of the experiments, interpreted the results, and wrote the draft of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5857585	29593754	SL	2	supervised and conceptualized the study and finalized the paper	supervised and conceptualized the study and finalized the paper	Conceived and designed the experiments|Wrote the paper	Conceptualization|Supervision|Writing - Review & Editing	YES
5857585	29593754	X-XZ	2	assisted in some experiments and helped analyze the data	assisted in some experiments and helped analyze the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5857585	29593754	Y-PL	2	assisted in some experiments and helped analyze the data	assisted in some experiments and helped analyze the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5857585	29593754	Y-WY	2	designed and conducted most of the experiments, interpreted the results, and wrote the draft of the manuscript	designed and conducted most of the experiments, interpreted the results, and wrote the draft of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
3914530	24293318	AB	PLoS52	designed the experiments|conducted the experiments|analysed data	designed the experiments	Conceived and designed the experiments	Methodology	YES
3914530	24293318	AB	PLoS52	designed the experiments|conducted the experiments|analysed data	conducted the experiments	Performed the experiments	Investigation	YES
3914530	24293318	AB	PLoS52	designed the experiments|conducted the experiments|analysed data	analysed data	Analyzed the data	Formal analysis	YES
3914530	24293318	CZ	PLoS52	contributed new reagents/analytic tools	contributed new reagents/analytic tools	Contributed reagents/materials/analysis tools	Resources	YES
3914530	24293318	GAG	PLoS52	conducted the experiments	conducted the experiments	Performed the experiments	Investigation	YES
3914530	24293318	GL	PLoS52	contributed new reagents/analytic tools	contributed new reagents/analytic tools	Contributed reagents/materials/analysis tools	Resources	YES
3914530	24293318	JKH	PLoS52	contributed new reagents/analytic tools	contributed new reagents/analytic tools	Contributed reagents/materials/analysis tools	Resources	YES
3914530	24293318	JR	PLoS52	conducted the experiments	conducted the experiments	Performed the experiments	Investigation	YES
3914530	24293318	MJR	PLoS52	contributed new reagents/analytic tools	contributed new reagents/analytic tools	Contributed reagents/materials/analysis tools	Resources	YES
3914530	24293318	MPH	PLoS52	conducted the experiments	conducted the experiments	Performed the experiments	Investigation	YES
3914530	24293318	MRK	PLoS52	designed the experiments|analysed data|wrote the paper	designed the experiments	Conceived and designed the experiments	Methodology	YES
3914530	24293318	MRK	PLoS52	designed the experiments|analysed data|wrote the paper	analysed data	Analyzed the data	Formal analysis	YES
3914530	24293318	MRK	PLoS52	designed the experiments|analysed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3914530	24293318	MWBT	PLoS52	conducted the experiments|analysed data	conducted the experiments	Performed the experiments	Investigation	YES
3914530	24293318	MWBT	PLoS52	conducted the experiments|analysed data	analysed data	Analyzed the data	Formal analysis	YES
3914530	24293318	RJMF	PLoS52	analysed data|wrote the paper	analysed data	Analyzed the data	Formal analysis	YES
3914530	24293318	RJMF	PLoS52	analysed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
3914530	24293318	SM	PLoS52	analysed data	analysed data	Analyzed the data	Formal analysis	YES
3914530	24293318	YAS	PLoS52	designed the experiments|conducted the experiments|analysed data|wrote the paper	designed the experiments	Conceived and designed the experiments	Methodology	YES
3914530	24293318	YAS	PLoS52	designed the experiments|conducted the experiments|analysed data|wrote the paper	conducted the experiments	Performed the experiments	Investigation	YES
3914530	24293318	YAS	PLoS52	designed the experiments|conducted the experiments|analysed data|wrote the paper	analysed data	Analyzed the data	Formal analysis	YES
3914530	24293318	YAS	PLoS52	designed the experiments|conducted the experiments|analysed data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6172163	30288622	All	2	data and materials are available on request	data and materials are available on request	-	-	NO
6172163	30288622	All authors	2	have contributed to this work|read and approved the final manuscript	have contributed to this work	-	-	NO
6172163	30288622	All authors	2	have contributed to this work|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6172163	30288622	Charles E. Milliken	2	whose friendship and love for science will be truly missed	whose friendship and love for science will be truly missed	-	-	NO
6172163	30288622	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
2043493	17987109	DV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2043493	17987109	DV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2043493	17987109	DV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2043493	17987109	DV	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2043493	17987109	LM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2043493	17987109	LM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2043493	17987109	LM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2043493	17987109	LM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2043493	17987109	RD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2043493	17987109	RD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2043493	17987109	RD	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5134681	28076929	FK	2	leading of the ankylosing project	leading of the ankylosing project	-	-	NO
5134681	28076929	JD	2	development of the model and managing of animal experiment	development of the model and managing of animal experiment	Performed the experiments	Investigation|Methodology	YES
5134681	28076929	MRI	2	acquisitions and study coordination	acquisitions and study coordination	-	Project administration	YES
5134681	28076929	NA	2	all histological analyses	all histological analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5134681	28076929	NB	2	acquisitions and study coordination	acquisitions and study coordination	-	Project administration	YES
5941172	29735731	All the authors	PLoS52	gave their final approval for publication	gave their final approval for publication	-	-	NO
5941172	29735731	I.B.	PLoS52	designed and led the study|analysed the data|contributed to the writing of the manuscript	designed and led the study	Conceived and designed the experiments	Methodology	YES
5941172	29735731	I.B.	PLoS52	designed and led the study|analysed the data|contributed to the writing of the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
5941172	29735731	I.B.	PLoS52	designed and led the study|analysed the data|contributed to the writing of the manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5941172	29735731	L.P.	PLoS52	did the computations|analysed the data|contributed to the writing of the manuscript	did the computations	-	Formal analysis	YES
5941172	29735731	L.P.	PLoS52	did the computations|analysed the data|contributed to the writing of the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
5941172	29735731	L.P.	PLoS52	did the computations|analysed the data|contributed to the writing of the manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5941172	29735731	M.H.C.	PLoS52	analysed the data|contributed to the writing of the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
5941172	29735731	M.H.C.	PLoS52	analysed the data|contributed to the writing of the manuscript	contributed to the writing of the manuscript	Wrote the paper	Writing - Original Draft	YES
5941172	29735731	S.Z.	PLoS52	did the computations|analysed the data	did the computations	-	Formal analysis	YES
5941172	29735731	S.Z.	PLoS52	did the computations|analysed the data	analysed the data	Analyzed the data	Formal analysis	YES
4420247	25942498	DB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4420247	25942498	DB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4420247	25942498	DB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4420247	25942498	DB	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4420247	25942498	JA	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4420247	25942498	JA	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4420247	25942498	JJ	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4420247	25942498	JJ	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4420247	25942498	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4420247	25942498	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4420247	25942498	JM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4420247	25942498	JRN	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4420247	25942498	JRN	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4420247	25942498	LI	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4420247	25942498	LI	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4420247	25942498	MG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4420247	25942498	MG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4420247	25942498	MG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4420247	25942498	MG	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4420247	25942498	MP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4420247	25942498	MP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4420247	25942498	MP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4420247	25942498	MP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4420247	25942498	RKG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4420247	25942498	RKG	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4420247	25942498	RWK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4420247	25942498	RWK	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5941608	29760928	TO	2	drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
5941608	29760928	YK	2	supervised the manuscript	supervised the manuscript	-	Supervision	YES
5963052	29796283	AN	2	conceived of the study, participated in its design and coordination, and drafted the manuscript	conceived of the study, participated in its design and coordination, and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
5963052	29796283	DC	2	conceived the study and participated in its design and coordination	conceived the study and participated in its design and coordination	Conceived and designed the experiments	Conceptualization|Methodology|Project administration	YES
5857590	29593758	BW	2	participated in parts of the experiments	participated in parts of the experiments	Performed the experiments	Investigation	YES
5857590	29593758	CZ	2	conceived and designed the research|revised the manuscript	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5857590	29593758	CZ	2	conceived and designed the research|revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5857590	29593758	HD	2	participated in parts of the experiments	participated in parts of the experiments	Performed the experiments	Investigation	YES
5857590	29593758	WL	2	participated in parts of the experiments	participated in parts of the experiments	Performed the experiments	Investigation	YES
5857590	29593758	XL	2	conceived and designed the research|conducted the experiments and analyzed the data	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5857590	29593758	XL	2	conceived and designed the research|conducted the experiments and analyzed the data	conducted the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5857590	29593758	YK	2	conceived and designed the research|conducted the experiments and analyzed the data|drafted the manuscript	conceived and designed the research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5857590	29593758	YK	2	conceived and designed the research|conducted the experiments and analyzed the data|drafted the manuscript	conducted the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5857590	29593758	YK	2	conceived and designed the research|conducted the experiments and analyzed the data|drafted the manuscript	drafted the manuscript	Wrote the paper	Writing - Original Draft	YES
6270943	25105920	A.F.	PLoS52	designed the experiments|performed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
6270943	25105920	A.F.	PLoS52	designed the experiments|performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
6270943	25105920	G.A.	PLoS52	did histopatology analysis and scoring	did histopatology analysis and scoring	-	-	NO
6270943	25105920	H.S.	PLoS52	designed the experiments|performed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
6270943	25105920	H.S.	PLoS52	designed the experiments|performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
6270943	25105920	M.G.	PLoS52	performed spectroscopic studies and transaminase measurement	performed spectroscopic studies and transaminase measurement	Performed the experiments	Investigation	YES
6270943	25105920	N.S.	PLoS52	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
6270943	25105920	P.K.	PLoS52	designed the experiments|did data analysis	designed the experiments	Conceived and designed the experiments	Methodology	YES
6270943	25105920	P.K.	PLoS52	designed the experiments|did data analysis	did data analysis	Analyzed the data	Formal analysis	YES
6270943	25105920	P.T.	PLoS52	performed the experiments|performed spectroscopic studies and transaminase measurement	performed the experiments	Performed the experiments	Investigation	YES
6270943	25105920	P.T.	PLoS52	performed the experiments|performed spectroscopic studies and transaminase measurement	performed spectroscopic studies and transaminase measurement	Performed the experiments	Investigation	YES
6270943	25105920	R.M.	PLoS52	designed the experiments|performed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
6270943	25105920	R.M.	PLoS52	designed the experiments|performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
6270943	25105920	R.S.	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
6270943	25105920	T.W.	PLoS52	performed spectroscopic studies and transaminase measurement	performed spectroscopic studies and transaminase measurement	Performed the experiments	Investigation	YES
5941174	29735733	GHL	2	made the distance measurements	made the distance measurements	Performed the experiments	Investigation	YES
5941174	29735733	XF	2	solved the crystal structure of the groel mutant k105a	solved the crystal structure of the groel mutant k105a	Performed the experiments	Investigation	YES
5941174	29735733	XY	2	established that the mutant k105a lacked negative cooperativity	established that the mutant k105a lacked negative cooperativity	Performed the experiments	Investigation	YES
4420249	25942686	AA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4420249	25942686	AA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4420249	25942686	AA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4420249	25942686	AA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4420249	25942686	CJN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4420249	25942686	CJN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4420249	25942686	CJN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4420249	25942686	CJN	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4420249	25942686	EMK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4420249	25942686	EMK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4420249	25942686	EMK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4420249	25942686	EMK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4420249	25942686	NA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4420249	25942686	NA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4420249	25942686	NA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4420249	25942686	NA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4420249	25942686	NSH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4420249	25942686	NSH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4420249	25942686	NSH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4420249	25942686	NSH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4420249	25942686	PSML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4420249	25942686	PSML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4420249	25942686	PSML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4420249	25942686	PSML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4420249	25942686	PYL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4420249	25942686	PYL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4420249	25942686	PYL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4420249	25942686	PYL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4420249	25942686	SML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4420249	25942686	SML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4420249	25942686	SML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4420249	25942686	SML	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4420249	25942686	SSLW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4420249	25942686	SSLW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4420249	25942686	SSLW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4420249	25942686	SSLW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4420249	25942686	YCC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4420249	25942686	YCC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4420249	25942686	YCC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5134682	28076928	AP	2	experiments performing	experiments performing	Performed the experiments	Investigation	YES
5134682	28076928	JK	2	study design, manuscript writing	study design, manuscript writing	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5134682	28076928	MK	2	manuscript critical revision for important intellectual content	manuscript critical revision for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5134682	28076928	RH	2	experiments performing	experiments performing	Performed the experiments	Investigation	YES
5134682	28076928	SH	2	manuscript critical revision for important intellectual content	manuscript critical revision for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5134682	28076928	UJ	2	study design, manuscript writing	study design, manuscript writing	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
6175732	30298308	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6175732	30298308	KT	2	did the sampling|wrote the manuscript	did the sampling	Performed the experiments	Investigation	YES
6175732	30298308	KT	2	did the sampling|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6175732	30298308	NSK	2	designed the study|did all pre-sequencing work for the illumina and data analysis	designed the study	Conceived and designed the experiments	Methodology	YES
6175732	30298308	NSK	2	designed the study|did all pre-sequencing work for the illumina and data analysis	did all pre-sequencing work for the illumina and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6175732	30298308	RBM	2	analyzed the esi -ms data|wrote the manuscript	analyzed the esi -ms data	Analyzed the data	Formal analysis	YES
6175732	30298308	RBM	2	analyzed the esi -ms data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6175732	30298308	SDM	2	designed the study|did all pre-sequencing work for the illumina and data analysis|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
6175732	30298308	SDM	2	designed the study|did all pre-sequencing work for the illumina and data analysis|wrote the manuscript	did all pre-sequencing work for the illumina and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6175732	30298308	SDM	2	designed the study|did all pre-sequencing work for the illumina and data analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6175732	30298308	SSS	2	did the sampling	did the sampling	Performed the experiments	Investigation	YES
6175732	30298308	VK	2	did all pre-sequencing work for the illumina and data analysis|wrote the manuscript	did all pre-sequencing work for the illumina and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6175732	30298308	VK	2	did all pre-sequencing work for the illumina and data analysis|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5964884	29850022	KS	2	revised and edited the manuscript	revised and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5964884	29850022	TH	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5964884	29850022	YK	2	revised and edited the manuscript	revised and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5964884	29850022	YM	2	revised and edited the manuscript	revised and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5857591	29593762	MW	2	performed the research and conducted the data analyses	performed the research and conducted the data analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5857591	29593762	YW	2	performed the research and conducted the data analyses	performed the research and conducted the data analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5857591	29593762	ZXia	2	designed the research|performed the research and conducted the data analyses|wrote and revised the manuscript	designed the research	Conceived and designed the experiments	Methodology	YES
5857591	29593762	ZXia	2	designed the research|performed the research and conducted the data analyses|wrote and revised the manuscript	performed the research and conducted the data analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5857591	29593762	ZXia	2	designed the research|performed the research and conducted the data analyses|wrote and revised the manuscript	wrote and revised the manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5857591	29593762	ZXu	2	performed the research and conducted the data analyses	performed the research and conducted the data analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
2043494	17987123	ET	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2043494	17987123	ET	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2043494	17987123	ET	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2043494	17987123	ET	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2043494	17987123	ET	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2043494	17987123	JD	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2043494	17987123	MA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2043494	17987123	MA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2043494	17987123	MA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2043494	17987123	MA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2043494	17987123	MA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3914532	24293317	AM	4	Experiments were designed and performed by	Experiments were designed and performed by	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3914532	24293317	CMC	4	muscle analysis was carried out by	muscle analysis was carried out by	Performed the experiments	Investigation	YES
3914532	24293317	DF	4	Mouse lines were generated by	Mouse lines were generated by	Performed the experiments	Investigation	YES
3914532	24293317	HA	4	Cardiac studies were planned and performed by	Cardiac studies were planned and performed by	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
3914532	24293317	HH	4	Mouse lines were generated by	Mouse lines were generated by	Performed the experiments	Investigation	YES
3914532	24293317	HK	4	Cardiac studies were planned and performed by	Cardiac studies were planned and performed by	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
3914532	24293317	KC	4	Mouse lines were generated by	Mouse lines were generated by	Performed the experiments	Investigation	YES
3914532	24293317	KYL	4	Mouse lines were generated by|Experiments were designed and performed by|muscle analysis was carried out by|The manuscript was prepared by	Mouse lines were generated by	Performed the experiments	Investigation	YES
3914532	24293317	KYL	4	Mouse lines were generated by|Experiments were designed and performed by|muscle analysis was carried out by|The manuscript was prepared by	Experiments were designed and performed by	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3914532	24293317	KYL	4	Mouse lines were generated by|Experiments were designed and performed by|muscle analysis was carried out by|The manuscript was prepared by	muscle analysis was carried out by	Performed the experiments	Investigation	YES
3914532	24293317	KYL	4	Mouse lines were generated by|Experiments were designed and performed by|muscle analysis was carried out by|The manuscript was prepared by	The manuscript was prepared by	Wrote the paper	Writing - Original Draft	YES
3914532	24293317	LPWR	4	muscle analysis was carried out by	muscle analysis was carried out by	Performed the experiments	Investigation	YES
3914532	24293317	ML	4	Experiments were designed and performed by|Cardiac studies were planned and performed by|muscle analysis was carried out by	Experiments were designed and performed by	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3914532	24293317	ML	4	Experiments were designed and performed by|Cardiac studies were planned and performed by|muscle analysis was carried out by	Cardiac studies were planned and performed by	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
3914532	24293317	ML	4	Experiments were designed and performed by|Cardiac studies were planned and performed by|muscle analysis was carried out by	muscle analysis was carried out by	Performed the experiments	Investigation	YES
3914532	24293317	MM	4	Experiments were designed and performed by	Experiments were designed and performed by	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3914532	24293317	MSS	4	The manuscript was prepared by	The manuscript was prepared by	Wrote the paper	Writing - Original Draft	YES
3914532	24293317	RB	4	Experiments were designed and performed by	Experiments were designed and performed by	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3914532	24293317	SAW	4	Cardiac studies were planned and performed by	Cardiac studies were planned and performed by	Conceived and designed the experiments|Performed the experiments	Conceptualization|Investigation	YES
4640231	26501770	R.A.C.	2	contributed equally	contributed equally	-	-	NO
4640231	26501770	S.A.L.	2	contributed equally	contributed equally	-	-	NO
5863459	29562889	BNL	2	performed experimental work	performed experimental work	Performed the experiments	Investigation	YES
5863459	29562889	HYB	2	performed experimental work	performed experimental work	Performed the experiments	Investigation	YES
5863459	29562889	JXL	2	did the bioinformatics analysis	did the bioinformatics analysis	-	Formal analysis	YES
5863459	29562889	LG	2	performed experimental work	performed experimental work	Performed the experiments	Investigation	YES
5863459	29562889	YJH	2	designed the study, interpreted the data and wrote the manuscript|did the bioinformatics analysis	designed the study, interpreted the data and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5863459	29562889	YJH	2	designed the study, interpreted the data and wrote the manuscript|did the bioinformatics analysis	did the bioinformatics analysis	-	Formal analysis	YES
6270944	24979404	DW	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
6270944	24979404	FF	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
6270944	24979404	FW	PLoS52	designed research and analyzed the data	designed research and analyzed the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
6270944	24979404	HW	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
6270944	24979404	JL	PLoS52	designed research and analyzed the data|wrote the paper	designed research and analyzed the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
6270944	24979404	JL	PLoS52	designed research and analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270944	24979404	TW	PLoS52	designed research and analyzed the data|wrote the paper	designed research and analyzed the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
6270944	24979404	TW	PLoS52	designed research and analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5857597	29593759	GY	2	collected the data and data analysis	collected the data and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5857597	29593759	JS	2	collected the data and data analysis	collected the data and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5857597	29593759	XL	2	collected the data and data analysis	collected the data and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4420250	25942561	BOE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4420250	25942561	BOE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4420250	25942561	BOE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4420250	25942561	BOE	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4420250	25942561	KDT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4420250	25942561	KDT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4420250	25942561	KDT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4420250	25942561	KDT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4420250	25942561	PRH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4420250	25942561	PRH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4420250	25942561	PRH	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2043495	17987124	EM	PLoS5	Performed some experiments	Performed some experiments	Performed the experiments	Investigation	YES
2043495	17987124	FV	PLoS5	Performed some experiments	Performed some experiments	Performed the experiments	Investigation	YES
2043495	17987124	JG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2043495	17987124	JG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2043495	17987124	JG	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2043495	17987124	MF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2043495	17987124	MF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2043495	17987124	MF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2043495	17987124	MF	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2043495	17987124	VC	PLoS5	Performed some experiments	Performed some experiments	Performed the experiments	Investigation	YES
5974442	29786554	A.F.	2	designed and performed cell culture experiments and analysed data	designed and performed cell culture experiments and analysed data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5974442	29786554	A.H.T.	2	performed cell culture experiments	performed cell culture experiments	Performed the experiments	Investigation	YES
5974442	29786554	A.T.	2	designed and performed cell culture experiments and analysed data	designed and performed cell culture experiments and analysed data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5974442	29786554	D.H.	2	provided important intellectual input and final approval of the manuscript	provided important intellectual input and final approval of the manuscript	-	-	NO
5974442	29786554	J.M.-R.	2	designed and performed cell culture experiments and analysed data	designed and performed cell culture experiments and analysed data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5974442	29786554	J.W.P.	2	provided important intellectual input and final approval of the manuscript	provided important intellectual input and final approval of the manuscript	-	-	NO
5974442	29786554	L.C.	2	designed and performed cell culture experiments and analysed data	designed and performed cell culture experiments and analysed data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5974442	29786554	L.M.F.	2	designed the experiments, analysed data and wrote the manuscript	designed the experiments, analysed data and wrote the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5974442	29786554	M.L.-Y.	2	designed and performed cell culture experiments and analysed data	designed and performed cell culture experiments and analysed data	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
5974442	29786554	R.A.A.	2	designed and generated the sfci55zsg cell line	designed and generated the sfci55zsg cell line	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5974442	29786554	V.W.	2	provided important intellectual input and final approval of the manuscript	provided important intellectual input and final approval of the manuscript	-	-	NO
6182018	30311091	All authors	2	read and approved the final manuscript|declare consent for publication	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6182018	30311091	All authors	2	read and approved the final manuscript|declare consent for publication	declare consent for publication	-	-	NO
6182018	30311091	All the authors	2	contributed to the construction of this manuscript, both in intellectual form and in preparation and accomplishment of the experiments and interpretation of dates	contributed to the construction of this manuscript, both in intellectual form and in preparation and accomplishment of the experiments and interpretation of dates	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6182018	30311091	The authors	2	declare that they have competing interests	declare that they have competing interests	-	-	NO
3914534	24293316	AB	2	designed the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
3914534	24293316	AP	2	designed the experiments|performed most of the experiments|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
3914534	24293316	AP	2	designed the experiments|performed most of the experiments|wrote the manuscript	performed most of the experiments	Performed the experiments	Investigation	YES
3914534	24293316	AP	2	designed the experiments|performed most of the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3914534	24293316	BG	2	designed the experiments|performed most of the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
3914534	24293316	BG	2	designed the experiments|performed most of the experiments	performed most of the experiments	Performed the experiments	Investigation	YES
3914534	24293316	CK	2	provided useful insights	provided useful insights	-	-	NO
3914534	24293316	DN	2	designed the experiments|performed most of the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
3914534	24293316	DN	2	designed the experiments|performed most of the experiments	performed most of the experiments	Performed the experiments	Investigation	YES
3914534	24293316	EC	2	designed the experiments|performed most of the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
3914534	24293316	EC	2	designed the experiments|performed most of the experiments	performed most of the experiments	Performed the experiments	Investigation	YES
3914534	24293316	ER	2	designed the experiments|performed most of the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
3914534	24293316	ER	2	designed the experiments|performed most of the experiments	performed most of the experiments	Performed the experiments	Investigation	YES
3914534	24293316	GD	2	designed the experiments|performed most of the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
3914534	24293316	GD	2	designed the experiments|performed most of the experiments	performed most of the experiments	Performed the experiments	Investigation	YES
3914534	24293316	GN	2	provided useful insights	provided useful insights	-	-	NO
3914534	24293316	IT	2	designed the experiments|performed immunostaining analysis	designed the experiments	Conceived and designed the experiments	Methodology	YES
3914534	24293316	IT	2	designed the experiments|performed immunostaining analysis	performed immunostaining analysis	Performed the experiments	Investigation	YES
3914534	24293316	MC	2	designed the experiments|performed most of the experiments	designed the experiments	Conceived and designed the experiments	Methodology	YES
3914534	24293316	MC	2	designed the experiments|performed most of the experiments	performed most of the experiments	Performed the experiments	Investigation	YES
3914534	24293316	PC	2	provided materials|provided useful insights	provided materials	Contributed reagents/materials/analysis tools	Resources	YES
3914534	24293316	PC	2	provided materials|provided useful insights	provided useful insights	-	-	NO
3914534	24293316	PM	2	designed the experiments|wrote the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
3914534	24293316	PM	2	designed the experiments|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6270945	25532839	AR	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
6270945	25532839	CC	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
6270945	25532839	CGB	PLoS52	designed research|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
6270945	25532839	CGB	PLoS52	designed research|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270945	25532839	GFB	PLoS52	performed research	performed research	Performed the experiments	Investigation	YES
6270945	25532839	JA	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
6270945	25532839	MF	PLoS52	designed research|performed research|analyzed the data|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
6270945	25532839	MF	PLoS52	designed research|performed research|analyzed the data|wrote the paper	performed research	Performed the experiments	Investigation	YES
6270945	25532839	MF	PLoS52	designed research|performed research|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
6270945	25532839	MF	PLoS52	designed research|performed research|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270945	25532839	MP	PLoS52	designed research|analyzed the data|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
6270945	25532839	MP	PLoS52	designed research|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
6270945	25532839	MP	PLoS52	designed research|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4420251	25941808	AD	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4420251	25941808	Abhishek Mishra	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4420251	25941808	Anshuman Mishra	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4420251	25941808	Anshuman Mishra	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4420251	25941808	Anshuman Mishra	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4420251	25941808	Anshuman Mishra	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4420251	25941808	DVSS	PLoS5	Silico analysis of variants	Silico analysis of variants	-	-	NO
4420251	25941808	GA	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4420251	25941808	HD	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4420251	25941808	KT	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4420251	25941808	KT	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4420251	25941808	NCT	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4420251	25941808	NRP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4420251	25941808	SN	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4420251	25941808	SN	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4420251	25941808	SN	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4420251	25941808	SP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5863803	29566661	CK	PLoS52	performed the experiments|analysed the data|interpreted the data and wrote the manuscript	performed the experiments	Performed the experiments	Investigation	YES
5863803	29566661	CK	PLoS52	performed the experiments|analysed the data|interpreted the data and wrote the manuscript	analysed the data	Analyzed the data	Formal analysis	YES
5863803	29566661	CK	PLoS52	performed the experiments|analysed the data|interpreted the data and wrote the manuscript	interpreted the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5863803	29566661	EB	PLoS52	designed experiments|interpreted the data and wrote the manuscript	designed experiments	Conceived and designed the experiments	Methodology	YES
5863803	29566661	EB	PLoS52	designed experiments|interpreted the data and wrote the manuscript	interpreted the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5863803	29566661	HMH	PLoS52	performed the metabolomics analysis	performed the metabolomics analysis	Performed the experiments	Investigation	YES
5863803	29566661	JV	PLoS52	interpreted the data and wrote the manuscript	interpreted the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5863803	29566661	MVAP	PLoS52	performed the bioinformatics analysis	performed the bioinformatics analysis	Performed the experiments	Formal analysis|Investigation	YES
5863803	29566661	MZ	PLoS52	performed the bioinformatics analysis	performed the bioinformatics analysis	Performed the experiments	Formal analysis|Investigation	YES
5863803	29566661	RPdV	PLoS52	conceived the study|designed experiments|interpreted the data and wrote the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5863803	29566661	RPdV	PLoS52	conceived the study|designed experiments|interpreted the data and wrote the manuscript	designed experiments	Conceived and designed the experiments	Methodology	YES
5863803	29566661	RPdV	PLoS52	conceived the study|designed experiments|interpreted the data and wrote the manuscript	interpreted the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5863803	29566661	RSK	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5863803	29566661	SD	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5863803	29566661	SEB	PLoS52	performed the metabolomics analysis	performed the metabolomics analysis	Performed the experiments	Investigation	YES
5863803	29566661	YMK	PLoS52	performed the metabolomics analysis	performed the metabolomics analysis	Performed the experiments	Investigation	YES
5857609	29593767	AG	2	performed phenotyping analysis in figure 1|performed transcripts stability assays in figures 3 4	performed phenotyping analysis in figure 1	Performed the experiments	Investigation|Visualization	YES
5857609	29593767	AG	2	performed phenotyping analysis in figure 1|performed transcripts stability assays in figures 3 4	performed transcripts stability assays in figures 3 4	Performed the experiments	Investigation|Visualization	YES
5857609	29593767	AK	2	to figure 4	to figure 4	-	Visualization	YES
5857609	29593767	DK	2	performed phenotyping analysis in figure 1	performed phenotyping analysis in figure 1	Performed the experiments	Investigation|Visualization	YES
5857609	29593767	IW	2	performed qrt pcrs, immunoblots, in-gel kinase assays in figures 3 - 5 , supplementary figures 1 , 2 , northern blots in supplementary figure 3 and contributed to figure 2|generated all figures|designed the project and wrote the manuscript	performed qrt pcrs, immunoblots, in-gel kinase assays in figures 3 - 5 , supplementary figures 1 , 2 , northern blots in supplementary figure 3 and contributed to figure 2	Performed the experiments	Investigation|Visualization	YES
5857609	29593767	IW	2	performed qrt pcrs, immunoblots, in-gel kinase assays in figures 3 - 5 , supplementary figures 1 , 2 , northern blots in supplementary figure 3 and contributed to figure 2|generated all figures|designed the project and wrote the manuscript	generated all figures	Performed the experiments	Investigation|Visualization	YES
5857609	29593767	IW	2	performed qrt pcrs, immunoblots, in-gel kinase assays in figures 3 - 5 , supplementary figures 1 , 2 , northern blots in supplementary figure 3 and contributed to figure 2|generated all figures|designed the project and wrote the manuscript	designed the project and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5857609	29593767	JK	2	designed the project and wrote the manuscript	designed the project and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5178803	28076936	AC	2	experimental procedures, immunohistochemical processing|microscopic analysis, data collection and/or preparation of figures	experimental procedures, immunohistochemical processing	Performed the experiments	Investigation	YES
5178803	28076936	AC	2	experimental procedures, immunohistochemical processing|microscopic analysis, data collection and/or preparation of figures	microscopic analysis, data collection and/or preparation of figures	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
5178803	28076936	AF	2	experimental procedures, immunohistochemical processing|microscopic analysis, data collection and/or preparation of figures	experimental procedures, immunohistochemical processing	Performed the experiments	Investigation	YES
5178803	28076936	AF	2	experimental procedures, immunohistochemical processing|microscopic analysis, data collection and/or preparation of figures	microscopic analysis, data collection and/or preparation of figures	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
5178803	28076936	All authors	2	have reviewed and contributed to the different draft versions of the manuscript and have read and approved the final manuscript	have reviewed and contributed to the different draft versions of the manuscript and have read and approved the final manuscript	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5178803	28076936	FSD	2	study design	study design	Conceived and designed the experiments	Methodology	YES
5178803	28076936	GA	2	study design	study design	Conceived and designed the experiments	Methodology	YES
5178803	28076936	GC	2	study design|microscopic analysis, data collection and/or preparation of figures	study design	Conceived and designed the experiments	Methodology	YES
5178803	28076936	GC	2	study design|microscopic analysis, data collection and/or preparation of figures	microscopic analysis, data collection and/or preparation of figures	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
5178803	28076936	GR	2	experimental procedures, immunohistochemical processing|microscopic analysis, data collection and/or preparation of figures	experimental procedures, immunohistochemical processing	Performed the experiments	Investigation	YES
5178803	28076936	GR	2	experimental procedures, immunohistochemical processing|microscopic analysis, data collection and/or preparation of figures	microscopic analysis, data collection and/or preparation of figures	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
5178803	28076936	GV	2	experimental procedures, immunohistochemical processing|microscopic analysis, data collection and/or preparation of figures	experimental procedures, immunohistochemical processing	Performed the experiments	Investigation	YES
5178803	28076936	GV	2	experimental procedures, immunohistochemical processing|microscopic analysis, data collection and/or preparation of figures	microscopic analysis, data collection and/or preparation of figures	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
5178803	28076936	LC	2	study design|collection of biopsies	study design	Conceived and designed the experiments	Methodology	YES
5178803	28076936	LC	2	study design|collection of biopsies	collection of biopsies	Performed the experiments	Investigation	YES
5178803	28076936	MR	2	collection of biopsies	collection of biopsies	Performed the experiments	Investigation	YES
5178803	28076936	RF	2	study design|collection of biopsies	study design	Conceived and designed the experiments	Methodology	YES
5178803	28076936	RF	2	study design|collection of biopsies	collection of biopsies	Performed the experiments	Investigation	YES
2047340	17973026	BH	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2047340	17973026	SA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2047340	17973026	SA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2047340	17973026	SA	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6182021	30311028	All	PLoS52	data analyzed in this article are included in the figures and tables	data analyzed in this article are included in the figures and tables	Analyzed the data	Formal analysis|Visualization	YES
6182021	30311028	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6182021	30311028	JL	PLoS52	designed the experiments|organized the implementation of field trials|wrote the paper|are in the interpretation of results and modification of the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
6182021	30311028	JL	PLoS52	designed the experiments|organized the implementation of field trials|wrote the paper|are in the interpretation of results and modification of the manuscript	organized the implementation of field trials	Performed the experiments	Investigation|Project administration	YES
6182021	30311028	JL	PLoS52	designed the experiments|organized the implementation of field trials|wrote the paper|are in the interpretation of results and modification of the manuscript	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6182021	30311028	JL	PLoS52	designed the experiments|organized the implementation of field trials|wrote the paper|are in the interpretation of results and modification of the manuscript	are in the interpretation of results and modification of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
6182021	30311028	LXZ	PLoS52	are in the interpretation of results and modification of the manuscript	are in the interpretation of results and modification of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
6182021	30311028	PZ	PLoS52	designed the experiments|analyzed the data|are in the interpretation of results and modification of the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
6182021	30311028	PZ	PLoS52	designed the experiments|analyzed the data|are in the interpretation of results and modification of the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
6182021	30311028	PZ	PLoS52	designed the experiments|analyzed the data|are in the interpretation of results and modification of the manuscript	are in the interpretation of results and modification of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
6182021	30311028	Public Welfare Industry	PLoS52	research project	research project	-	-	NO
6182021	30311028	RXX	PLoS52	designed the experiments|organized the implementation of field trials|wrote the paper|are in the interpretation of results and modification of the manuscript	designed the experiments	Conceived and designed the experiments	Methodology	YES
6182021	30311028	RXX	PLoS52	designed the experiments|organized the implementation of field trials|wrote the paper|are in the interpretation of results and modification of the manuscript	organized the implementation of field trials	Performed the experiments	Investigation|Project administration	YES
6182021	30311028	RXX	PLoS52	designed the experiments|organized the implementation of field trials|wrote the paper|are in the interpretation of results and modification of the manuscript	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6182021	30311028	RXX	PLoS52	designed the experiments|organized the implementation of field trials|wrote the paper|are in the interpretation of results and modification of the manuscript	are in the interpretation of results and modification of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
6182021	30311028	The authors	PLoS52	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
6182021	30311028	YG	PLoS52	conceived the study	conceived the study	Conceived and designed the experiments	Conceptualization	YES
6182021	30311028	YGG	PLoS52	analyzed the data|wrote the paper|are in the interpretation of results and modification of the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
6182021	30311028	YGG	PLoS52	analyzed the data|wrote the paper|are in the interpretation of results and modification of the manuscript	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6182021	30311028	YGG	PLoS52	analyzed the data|wrote the paper|are in the interpretation of results and modification of the manuscript	are in the interpretation of results and modification of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
6182021	30311028	YZ	PLoS52	analyzed the data|are in the interpretation of results and modification of the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
6182021	30311028	YZ	PLoS52	analyzed the data|are in the interpretation of results and modification of the manuscript	are in the interpretation of results and modification of the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
4420253	25942421	GG	PLoS5	Analyzed the data|Wrote the paper|Costing methodology design|Service liaison, cost data collection and processing|Performed economic analysis	Analyzed the data	Analyzed the data	Formal analysis	YES
4420253	25942421	GG	PLoS5	Analyzed the data|Wrote the paper|Costing methodology design|Service liaison, cost data collection and processing|Performed economic analysis	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4420253	25942421	GG	PLoS5	Analyzed the data|Wrote the paper|Costing methodology design|Service liaison, cost data collection and processing|Performed economic analysis	Costing methodology design	Conceived and designed the experiments|Performed the experiments	Methodology	YES
4420253	25942421	GG	PLoS5	Analyzed the data|Wrote the paper|Costing methodology design|Service liaison, cost data collection and processing|Performed economic analysis	Service liaison, cost data collection and processing	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
4420253	25942421	GG	PLoS5	Analyzed the data|Wrote the paper|Costing methodology design|Service liaison, cost data collection and processing|Performed economic analysis	Performed economic analysis	Performed the experiments	Investigation	YES
4420253	25942421	JE	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Literature search	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4420253	25942421	JE	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Literature search	Performed the experiments	Performed the experiments	Investigation	YES
4420253	25942421	JE	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Literature search	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4420253	25942421	JE	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Literature search	Literature search	-	Formal analysis	YES
4420253	25942421	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Economic analysis interpretation|Literature search	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4420253	25942421	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Economic analysis interpretation|Literature search	Performed the experiments	Performed the experiments	Investigation	YES
4420253	25942421	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Economic analysis interpretation|Literature search	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4420253	25942421	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Economic analysis interpretation|Literature search	Economic analysis interpretation	Analyzed the data	Formal analysis	YES
4420253	25942421	JG	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Economic analysis interpretation|Literature search	Literature search	-	Formal analysis	YES
4420253	25942421	LB	PLoS5	Wrote the paper|Clinical data preparation and processing	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4420253	25942421	LB	PLoS5	Wrote the paper|Clinical data preparation and processing	Clinical data preparation and processing	Analyzed the data	Data curation	YES
4420253	25942421	LT	PLoS5	Analyzed the data|Wrote the paper|Economic analysis conception and design|Performed economic analysis|Economic analysis interpretation|Literature search	Analyzed the data	Analyzed the data	Formal analysis	YES
4420253	25942421	LT	PLoS5	Analyzed the data|Wrote the paper|Economic analysis conception and design|Performed economic analysis|Economic analysis interpretation|Literature search	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4420253	25942421	LT	PLoS5	Analyzed the data|Wrote the paper|Economic analysis conception and design|Performed economic analysis|Economic analysis interpretation|Literature search	Economic analysis conception and design	Conceived and designed the experiments	Conceptualization	YES
4420253	25942421	LT	PLoS5	Analyzed the data|Wrote the paper|Economic analysis conception and design|Performed economic analysis|Economic analysis interpretation|Literature search	Performed economic analysis	Performed the experiments	Investigation	YES
4420253	25942421	LT	PLoS5	Analyzed the data|Wrote the paper|Economic analysis conception and design|Performed economic analysis|Economic analysis interpretation|Literature search	Economic analysis interpretation	Analyzed the data	Formal analysis	YES
4420253	25942421	LT	PLoS5	Analyzed the data|Wrote the paper|Economic analysis conception and design|Performed economic analysis|Economic analysis interpretation|Literature search	Literature search	-	Formal analysis	YES
4420253	25942421	MF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Costing methodology design|Service liaison, cost data collection and processing|Economic analysis conception and design|Performed economic analysis|Economic analysis interpretation|Literature search	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4420253	25942421	MF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Costing methodology design|Service liaison, cost data collection and processing|Economic analysis conception and design|Performed economic analysis|Economic analysis interpretation|Literature search	Analyzed the data	Analyzed the data	Formal analysis	YES
4420253	25942421	MF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Costing methodology design|Service liaison, cost data collection and processing|Economic analysis conception and design|Performed economic analysis|Economic analysis interpretation|Literature search	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4420253	25942421	MF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Costing methodology design|Service liaison, cost data collection and processing|Economic analysis conception and design|Performed economic analysis|Economic analysis interpretation|Literature search	Costing methodology design	Conceived and designed the experiments|Performed the experiments	Methodology	YES
4420253	25942421	MF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Costing methodology design|Service liaison, cost data collection and processing|Economic analysis conception and design|Performed economic analysis|Economic analysis interpretation|Literature search	Service liaison, cost data collection and processing	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
4420253	25942421	MF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Costing methodology design|Service liaison, cost data collection and processing|Economic analysis conception and design|Performed economic analysis|Economic analysis interpretation|Literature search	Economic analysis conception and design	Conceived and designed the experiments	Conceptualization	YES
4420253	25942421	MF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Costing methodology design|Service liaison, cost data collection and processing|Economic analysis conception and design|Performed economic analysis|Economic analysis interpretation|Literature search	Performed economic analysis	Performed the experiments	Investigation	YES
4420253	25942421	MF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Costing methodology design|Service liaison, cost data collection and processing|Economic analysis conception and design|Performed economic analysis|Economic analysis interpretation|Literature search	Economic analysis interpretation	Analyzed the data	Formal analysis	YES
4420253	25942421	MF	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Costing methodology design|Service liaison, cost data collection and processing|Economic analysis conception and design|Performed economic analysis|Economic analysis interpretation|Literature search	Literature search	-	Formal analysis	YES
4420253	25942421	RE	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Economic analysis conception and design|Economic analysis interpretation|Literature search	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4420253	25942421	RE	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Economic analysis conception and design|Economic analysis interpretation|Literature search	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4420253	25942421	RE	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Economic analysis conception and design|Economic analysis interpretation|Literature search	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4420253	25942421	RE	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Economic analysis conception and design|Economic analysis interpretation|Literature search	Economic analysis conception and design	Conceived and designed the experiments	Conceptualization	YES
4420253	25942421	RE	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Economic analysis conception and design|Economic analysis interpretation|Literature search	Economic analysis interpretation	Analyzed the data	Formal analysis	YES
4420253	25942421	RE	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper|Economic analysis conception and design|Economic analysis interpretation|Literature search	Literature search	-	Formal analysis	YES
4420253	25942421	SC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Literature search	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4420253	25942421	SC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Literature search	Performed the experiments	Performed the experiments	Investigation	YES
4420253	25942421	SC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Literature search	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4420253	25942421	SC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper|Literature search	Literature search	-	Formal analysis	YES
4420253	25942421	VB	PLoS5	Analyzed the data|Wrote the paper|Costing methodology design|Service liaison, cost data collection and processing|Performed economic analysis	Analyzed the data	Analyzed the data	Formal analysis	YES
4420253	25942421	VB	PLoS5	Analyzed the data|Wrote the paper|Costing methodology design|Service liaison, cost data collection and processing|Performed economic analysis	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4420253	25942421	VB	PLoS5	Analyzed the data|Wrote the paper|Costing methodology design|Service liaison, cost data collection and processing|Performed economic analysis	Costing methodology design	Conceived and designed the experiments|Performed the experiments	Methodology	YES
4420253	25942421	VB	PLoS5	Analyzed the data|Wrote the paper|Costing methodology design|Service liaison, cost data collection and processing|Performed economic analysis	Service liaison, cost data collection and processing	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
4420253	25942421	VB	PLoS5	Analyzed the data|Wrote the paper|Costing methodology design|Service liaison, cost data collection and processing|Performed economic analysis	Performed economic analysis	Performed the experiments	Investigation	YES
5870082	29580219	All authors	PLoS52	read, edited and approved the final manuscript	read, edited and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5870082	29580219	DHJ	PLoS52	contributed reagents/materials/analysis tools	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5870082	29580219	EVZ	PLoS52	conceived and designed the study|performed the experiments|analyzed the data|wrote the paper	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5870082	29580219	EVZ	PLoS52	conceived and designed the study|performed the experiments|analyzed the data|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5870082	29580219	EVZ	PLoS52	conceived and designed the study|performed the experiments|analyzed the data|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5870082	29580219	EVZ	PLoS52	conceived and designed the study|performed the experiments|analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5870082	29580219	JES	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5870082	29580219	JRD	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5870082	29580219	JRD	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5870082	29580219	NVI	PLoS52	performed the experiments|analyzed the data	performed the experiments	Performed the experiments	Investigation	YES
5870082	29580219	NVI	PLoS52	performed the experiments|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
5870082	29580219	PDNH	PLoS52	conceived and designed the study|wrote the paper	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
5870082	29580219	PDNH	PLoS52	conceived and designed the study|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5870082	29580219	SN	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5870082	29580219	SR	PLoS52	performed the experiments|analyzed the data|contributed reagents/materials/analysis tools	performed the experiments	Performed the experiments	Investigation	YES
5870082	29580219	SR	PLoS52	performed the experiments|analyzed the data|contributed reagents/materials/analysis tools	analyzed the data	Analyzed the data	Formal analysis	YES
5870082	29580219	SR	PLoS52	performed the experiments|analyzed the data|contributed reagents/materials/analysis tools	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5870082	29580219	SWJP	PLoS52	performed the experiments|analyzed the data|contributed reagents/materials/analysis tools|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5870082	29580219	SWJP	PLoS52	performed the experiments|analyzed the data|contributed reagents/materials/analysis tools|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5870082	29580219	SWJP	PLoS52	performed the experiments|analyzed the data|contributed reagents/materials/analysis tools|wrote the paper	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5870082	29580219	SWJP	PLoS52	performed the experiments|analyzed the data|contributed reagents/materials/analysis tools|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5870082	29580219	TWAB	PLoS52	performed the experiments|analyzed the data|contributed reagents/materials/analysis tools|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5870082	29580219	TWAB	PLoS52	performed the experiments|analyzed the data|contributed reagents/materials/analysis tools|wrote the paper	analyzed the data	Analyzed the data	Formal analysis	YES
5870082	29580219	TWAB	PLoS52	performed the experiments|analyzed the data|contributed reagents/materials/analysis tools|wrote the paper	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5870082	29580219	TWAB	PLoS52	performed the experiments|analyzed the data|contributed reagents/materials/analysis tools|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5870082	29580219	WH	PLoS52	contributed reagents/materials/analysis tools	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5178804	28076931	AJM	2	research design|manuscript writing	research design	Conceived and designed the experiments	-	YES
5178804	28076931	AJM	2	research design|manuscript writing	manuscript writing	Wrote the paper	Writing - Original Draft	YES
5178804	28076931	AM	2	manuscript writing	manuscript writing	Wrote the paper	Writing - Original Draft	YES
5178804	28076931	AS	2	commented on the manuscript	commented on the manuscript	-	-	NO
5178804	28076931	All authors	2	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5178804	28076931	DN	2	commented on the manuscript	commented on the manuscript	-	-	NO
6001072	29942519	All authors	2	read and approved the final manuscript|have agreed to be accountable for all aspects of the work|approve the order of authorship as listed in the manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6001072	29942519	All authors	2	read and approved the final manuscript|have agreed to be accountable for all aspects of the work|approve the order of authorship as listed in the manuscript	have agreed to be accountable for all aspects of the work	-	-	NO
6001072	29942519	All authors	2	read and approved the final manuscript|have agreed to be accountable for all aspects of the work|approve the order of authorship as listed in the manuscript	approve the order of authorship as listed in the manuscript	-	-	NO
6001072	29942519	EB	2	analyzed and interpreted the patient data regarding the rate of thromboembolism in patients who received anticoagulation reversal|were also major contributors in writing the manuscript	analyzed and interpreted the patient data regarding the rate of thromboembolism in patients who received anticoagulation reversal	Analyzed the data	Formal analysis	YES
6001072	29942519	EB	2	analyzed and interpreted the patient data regarding the rate of thromboembolism in patients who received anticoagulation reversal|were also major contributors in writing the manuscript	were also major contributors in writing the manuscript	Wrote the paper	Writing - Original Draft	YES
6001072	29942519	JT	2	made major contributions to the conception and design of the study|analyzed and interpreted the patient data regarding the rate of thromboembolism in patients who received anticoagulation reversal|were also major contributors in writing the manuscript	made major contributions to the conception and design of the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
6001072	29942519	JT	2	made major contributions to the conception and design of the study|analyzed and interpreted the patient data regarding the rate of thromboembolism in patients who received anticoagulation reversal|were also major contributors in writing the manuscript	analyzed and interpreted the patient data regarding the rate of thromboembolism in patients who received anticoagulation reversal	Analyzed the data	Formal analysis	YES
6001072	29942519	JT	2	made major contributions to the conception and design of the study|analyzed and interpreted the patient data regarding the rate of thromboembolism in patients who received anticoagulation reversal|were also major contributors in writing the manuscript	were also major contributors in writing the manuscript	Wrote the paper	Writing - Original Draft	YES
6001072	29942519	SA	2	performed the majority of intellectual editing and revision of the manuscript prior to submission	performed the majority of intellectual editing and revision of the manuscript prior to submission	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
6270946	25460309	C.H.	2	participated in the revision of the manuscript	participated in the revision of the manuscript	Wrote the paper	Writing - Review & Editing	YES
6270946	25460309	CMPCs	2	generated the graphs for proteomic data and wrote the manuscript	generated the graphs for proteomic data and wrote the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6270946	25460309	G.Y.	2	carried out ms identification	carried out ms identification	Performed the experiments	Investigation	YES
6270946	25460309	L.J.	2	participated in data analysis	participated in data analysis	Analyzed the data	Formal analysis	YES
6270946	25460309	T.M.	2	performed the preparation of cmpcs	performed the preparation of cmpcs	Performed the experiments	Investigation	YES
6270946	25460309	Y.Z.	2	participated in the culture and stimulation of lx-2 cells	participated in the culture and stimulation of lx-2 cells	Performed the experiments	Investigation	YES
6270946	25460309	Z.L.	2	participated in the design of the project, coordination and helped to draft the manuscript	participated in the design of the project, coordination and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Project administration|Writing - Original Draft	YES
2048575	17987110	HM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
2048575	17987110	HM	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2048575	17987110	JL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2048575	17987110	JL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2048575	17987110	JL	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2048575	17987110	LZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
2048575	17987110	ML	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
2048575	17987110	MM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2048575	17987110	MM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2048575	17987110	MM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2048575	17987110	MZ	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2048575	17987110	QC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
2048575	17987110	QC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2048575	17987110	UR	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
2048575	17987110	WH	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2048575	17987110	XW	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2048575	17987110	XZ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
2048575	17987110	XZ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
2048575	17987110	XZ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2048575	17987110	YG	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
2048575	17987110	YZ	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2048575	17987110	YZ	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4677169	26697483	Weixia Jing	PLoS52	performed the experiments|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
4677169	26697483	Weixia Jing	PLoS52	performed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4677169	26697483	Wenyan Sun	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
4677169	26697483	Xiujuan Hou	PLoS52	assisted in data analysis	assisted in data analysis	Analyzed the data	Formal analysis	YES
4677169	26697483	Xuewu Zhang	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
4677169	26697483	Yuelan Zhu	PLoS52	designed the overall experiments|wrote the paper	designed the overall experiments	Conceived and designed the experiments	Methodology	YES
4677169	26697483	Yuelan Zhu	PLoS52	designed the overall experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
4677169	26697483	Zhongqiang Yao	PLoS52	assisted in data analysis	assisted in data analysis	Analyzed the data	Formal analysis	YES
5859031	29593771	All authors	2	listed have made a substantial, direct and intellectual contribution to the work, and approved it for publication	listed have made a substantial, direct and intellectual contribution to the work, and approved it for publication	-	-	NO
5859031	29593771	The authors	2	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	Performed the experiments	Investigation	YES
5974453	29786565	A.J.D.	2	conceived the experiments, was involved in scientific design and data analysis and co-authored the manuscript	conceived the experiments, was involved in scientific design and data analysis and co-authored the manuscript	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
5974453	29786565	All authors	2	contributed to drafts of the manuscript and approved the final version	contributed to drafts of the manuscript and approved the final version	Wrote the paper	Writing - Original Draft	YES
5974453	29786565	B.L.V.	2	were involved in stem cell maintenance, differentiation and phenotyping	were involved in stem cell maintenance, differentiation and phenotyping	Performed the experiments	Investigation	YES
5974453	29786565	D.C.H.	2	was involved in experimental design, data interpretation, manuscript writing and provided support, reagents and tools for hlc experiments	was involved in experimental design, data interpretation, manuscript writing and provided support, reagents and tools for hlc experiments	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Methodology|Resources|Writing - Original Draft	YES
5974453	29786565	D.S.	2	were involved in stem cell maintenance, differentiation and phenotyping	were involved in stem cell maintenance, differentiation and phenotyping	Performed the experiments	Investigation	YES
5974453	29786565	E.O.	2	aided in the automation of the hepatocyte differentiation process and data analysis	aided in the automation of the hepatocyte differentiation process and data analysis	Analyzed the data	Data curation|Formal analysis	YES
5974453	29786565	G.R.B.	2	were involved in metabolomics experiments	were involved in metabolomics experiments	-	-	NO
5974453	29786565	J.C.	2	were involved in metabolomics experiments	were involved in metabolomics experiments	-	-	NO
5974453	29786565	J.M.-R.	2	were involved in stem cell maintenance, differentiation and phenotyping	were involved in stem cell maintenance, differentiation and phenotyping	Performed the experiments	Investigation	YES
5974453	29786565	J.P.T.	2	was involved in experimental design, bioinformatics analysis and manuscript writing	was involved in experimental design, bioinformatics analysis and manuscript writing	Conceived and designed the experiments|Wrote the paper	Formal analysis|Methodology|Writing - Original Draft	YES
5974453	29786565	K.C.	2	was involved in experimental design, stem cell differentiation and phenotyping	was involved in experimental design, stem cell differentiation and phenotyping	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5974453	29786565	M.J.L.	2	was involved in scientific design, conducted experiments and bioinformatic analysis and co-authored the manuscript	was involved in scientific design, conducted experiments and bioinformatic analysis and co-authored the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5974453	29786565	R.R.M.	2	was involved in experimental design and manuscript writing	was involved in experimental design and manuscript writing	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5974453	29786565	W.B.D.	2	were involved in metabolomics experiments	were involved in metabolomics experiments	-	-	NO
5974453	29786565	Y.W.	2	were involved in stem cell maintenance, differentiation and phenotyping	were involved in stem cell maintenance, differentiation and phenotyping	Performed the experiments	Investigation	YES
6182024	30311044	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6182024	30311044	JL	2	conceived of the study, participated in its design and coordination, and drafted the manuscript	conceived of the study, participated in its design and coordination, and drafted the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
6182024	30311044	TC	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
6182024	30311044	XH	2	carried out the experiments	carried out the experiments	Performed the experiments	Investigation	YES
2048576	17987131	CP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2048576	17987131	CP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2048576	17987131	CP	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2048576	17987131	KE	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2048576	17987131	MS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
2048576	17987131	NN	PLoS5	Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2048576	17987131	OP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2048576	17987131	OP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
2048576	17987131	OP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2048576	17987131	PC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
2048576	17987131	RL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2048576	17987131	RL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
2048576	17987131	RL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2048576	17987131	SP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
2048576	17987131	WV	PLoS5	Conceived and designed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2048576	17987131	WV	PLoS5	Conceived and designed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
6019312	29983985	KDS	2	contributed to the study design|helped in manuscript preparation	contributed to the study design	Conceived and designed the experiments	Methodology	YES
6019312	29983985	KDS	2	contributed to the study design|helped in manuscript preparation	helped in manuscript preparation	Wrote the paper	Writing - Original Draft	YES
6019312	29983985	SB	2	helped in the data collection and data analysis|helped in manuscript preparation	helped in the data collection and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6019312	29983985	SB	2	helped in the data collection and data analysis|helped in manuscript preparation	helped in manuscript preparation	Wrote the paper	Writing - Original Draft	YES
6019312	29983985	SM	2	contributed to the study design|helped in the data collection and data analysis|helped in manuscript preparation	contributed to the study design	Conceived and designed the experiments	Methodology	YES
6019312	29983985	SM	2	contributed to the study design|helped in the data collection and data analysis|helped in manuscript preparation	helped in the data collection and data analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6019312	29983985	SM	2	contributed to the study design|helped in the data collection and data analysis|helped in manuscript preparation	helped in manuscript preparation	Wrote the paper	Writing - Original Draft	YES
6270947	24959679	De-Quan Sun	2	contributed to a partial of the experiment	contributed to a partial of the experiment	Performed the experiments	Investigation	YES
6270947	24959679	Guang-Ming Sun	2	participated in a partial of the work of technical guidance and subjects designing	participated in a partial of the work of technical guidance and subjects designing	Conceived and designed the experiments	Supervision	YES
6270947	24959679	Qing-Song Wu	2	contributed to a partial of the experiment	contributed to a partial of the experiment	Performed the experiments	Investigation	YES
6270947	24959679	Sheng-Hui Liu	2	contributed to a partial of the experiment	contributed to a partial of the experiment	Performed the experiments	Investigation	YES
6270947	24959679	Xin-Hua Lu	2	participated in the entire experiment and the manuscript writing	participated in the entire experiment and the manuscript writing	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5870100	29587635	AI	2	carried out species identification, microarray, qpcr, sequencing, genotyping, rnai-induced knockdown, and meta-analysis experiments, performed statistical analyses, participated in the design of the study, and drafted the manuscript	carried out species identification, microarray, qpcr, sequencing, genotyping, rnai-induced knockdown, and meta-analysis experiments, performed statistical analyses, participated in the design of the study, and drafted the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5870100	29587635	DR	2	designed and carried out in silico modelling experiments	designed and carried out in silico modelling experiments	Conceived and designed the experiments|Performed the experiments	Formal analysis|Investigation|Methodology	YES
5870100	29587635	HM	2	carried out sample collections	carried out sample collections	Performed the experiments	Investigation	YES
5870100	29587635	MD	2	conceived of the study, participated in its design and coordination, and helped to draft the manuscript	conceived of the study, participated in its design and coordination, and helped to draft the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Project administration|Writing - Original Draft	YES
5870100	29587635	ST	2	contributed to rnai-induced knockdown experiments	contributed to rnai-induced knockdown experiments	Performed the experiments	Investigation	YES
5870100	29587635	WHO	2	tube bioassays, and species identification	tube bioassays, and species identification	Performed the experiments	Investigation	YES
4420254	25942584	C-CH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4420254	25942584	C-CH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4420254	25942584	C-CH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4420254	25942584	C-CH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4420254	25942584	C-CH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4420254	25942584	H-CC	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4420254	25942584	HY-HL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4420254	25942584	HY-HL	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4420254	25942584	J-CH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4420254	25942584	J-CH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4420254	25942584	J-CH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4420254	25942584	J-CH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4420254	25942584	J-CH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4420254	25942584	J-CT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4420254	25942584	J-CT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4420254	25942584	J-CT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4420254	25942584	J-CT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4420254	25942584	J-CT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4420254	25942584	J-MC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4420254	25942584	J-MC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4420254	25942584	L-ML	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4420254	25942584	L-ML	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4420254	25942584	S-CC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4420254	25942584	S-CC	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4420254	25942584	S-JH	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5859231	29593755	AS	2	critically reviewed the data analysis and manuscript	critically reviewed the data analysis and manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5859231	29593755	PM	2	contributed to the genotypes sampling and study design|conducted the experiments, performed the data and sequence analysis, developed the hrm primers and wrote the main manuscript text	contributed to the genotypes sampling and study design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5859231	29593755	PM	2	contributed to the genotypes sampling and study design|conducted the experiments, performed the data and sequence analysis, developed the hrm primers and wrote the main manuscript text	conducted the experiments, performed the data and sequence analysis, developed the hrm primers and wrote the main manuscript text	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5859231	29593755	VS	2	contributed to the genotypes sampling and study design|critically reviewed the data analysis and manuscript	contributed to the genotypes sampling and study design	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5859231	29593755	VS	2	contributed to the genotypes sampling and study design|critically reviewed the data analysis and manuscript	critically reviewed the data analysis and manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
5289301	28348416	AG	2	helped with in vitro experiments and molecular biology	helped with in vitro experiments and molecular biology	Performed the experiments	Investigation	YES
5289301	28348416	EM	2	substantial contributions to the conception and design of study, immunohistochemical analysis performing, manuscript revision	substantial contributions to the conception and design of study, immunohistochemical analysis performing, manuscript revision	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Methodology|Writing - Review & Editing	YES
5289301	28348416	OT	2	helped revising the manuscript critically for important intellectual content	helped revising the manuscript critically for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5289301	28348416	PB	2	experiments conception and design, helped revising the manuscript	experiments conception and design, helped revising the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Review & Editing	YES
5289301	28348416	SG	2	manuscript writing, in vitro studies, molecular biology analysis and the statistical analysis	manuscript writing, in vitro studies, molecular biology analysis and the statistical analysis	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
3927953	24413190	AC	2	performed cytofluorimeter experiments	performed cytofluorimeter experiments	Performed the experiments	Investigation	YES
3927953	24413190	AM	2	performed the in vivo experiments|shared expertise and provided the vectors|designed and performed experiments in yeast|reviewed the manuscript	performed the in vivo experiments	Performed the experiments	Investigation	YES
3927953	24413190	AM	2	performed the in vivo experiments|shared expertise and provided the vectors|designed and performed experiments in yeast|reviewed the manuscript	shared expertise and provided the vectors	-	-	NO
3927953	24413190	AM	2	performed the in vivo experiments|shared expertise and provided the vectors|designed and performed experiments in yeast|reviewed the manuscript	designed and performed experiments in yeast	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3927953	24413190	AM	2	performed the in vivo experiments|shared expertise and provided the vectors|designed and performed experiments in yeast|reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
3927953	24413190	AN	2	shared expertise and provided the vectors	shared expertise and provided the vectors	-	-	NO
3927953	24413190	AP	2	performed the in vivo experiments	performed the in vivo experiments	Performed the experiments	Investigation	YES
3927953	24413190	AR	2	performed the mitochondrial import experiments	performed the mitochondrial import experiments	Performed the experiments	Investigation	YES
3927953	24413190	All authors	2	read and approved the final version of the manuscript	read and approved the final version of the manuscript	-	-	NO
3927953	24413190	CG	2	designed the experimental plan and wrote the manuscript	designed the experimental plan and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3927953	24413190	DG	2	shared expertise and provided the vectors	shared expertise and provided the vectors	-	-	NO
3927953	24413190	EP	2	performed the in vivo experiments|performed spr experiments|designed the experimental plan and wrote the manuscript	performed the in vivo experiments	Performed the experiments	Investigation	YES
3927953	24413190	EP	2	performed the in vivo experiments|performed spr experiments|designed the experimental plan and wrote the manuscript	performed spr experiments	Performed the experiments	Investigation	YES
3927953	24413190	EP	2	performed the in vivo experiments|performed spr experiments|designed the experimental plan and wrote the manuscript	designed the experimental plan and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3927953	24413190	GC	2	performed spr experiments	performed spr experiments	Performed the experiments	Investigation	YES
3927953	24413190	GdA	2	designed the experimental plan and wrote the manuscript	designed the experimental plan and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
3927953	24413190	HAT	2	verified the homoplasmic status of cybrids and performed the northern experiments	verified the homoplasmic status of cybrids and performed the northern experiments	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Validation	YES
3927953	24413190	LF	2	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
3927953	24413190	MO	2	performed immunofluorescence experiments	performed immunofluorescence experiments	Performed the experiments	Investigation	YES
3927953	24413190	MZ	2	reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
3927953	24413190	PDM	2	performed sequence and three dimensional structural analyses	performed sequence and three dimensional structural analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3927953	24413190	RNA	2	point mutations both in yeast and human cell lines|syntethases are able to improve both viability and bionergetic proficiency of human cells carrying pathogenic mutations in the mt-trna ile gene	point mutations both in yeast and human cell lines	Performed the experiments	Investigation	YES
3927953	24413190	RNA	2	point mutations both in yeast and human cell lines|syntethases are able to improve both viability and bionergetic proficiency of human cells carrying pathogenic mutations in the mt-trna ile gene	syntethases are able to improve both viability and bionergetic proficiency of human cells carrying pathogenic mutations in the mt-trna ile gene	Performed the experiments	Investigation	YES
3927953	24413190	RWT	2	verified the homoplasmic status of cybrids and performed the northern experiments	verified the homoplasmic status of cybrids and performed the northern experiments	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Validation	YES
3927953	24413190	SF	2	designed and performed experiments in yeast|reviewed the manuscript	designed and performed experiments in yeast	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
3927953	24413190	SF	2	designed and performed experiments in yeast|reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
3927953	24413190	VM	2	performed sequence and three dimensional structural analyses|reviewed the manuscript	performed sequence and three dimensional structural analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3927953	24413190	VM	2	performed sequence and three dimensional structural analyses|reviewed the manuscript	reviewed the manuscript	Wrote the paper	Writing - Review & Editing	YES
6186262	30317393	All authors	2	have revised the manuscript|read and approved the final manuscript	have revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
6186262	30317393	All authors	2	have revised the manuscript|read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6186262	30317393	HZ	2	helped with some experiments	helped with some experiments	Performed the experiments	Investigation	YES
6186262	30317393	JG	2	carried out the experiments and drafted the paper	carried out the experiments and drafted the paper	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6186262	30317393	LG	2	designed, supervised and provided technical expertise to the project|helped with some experiments	designed, supervised and provided technical expertise to the project	Conceived and designed the experiments	Methodology|Supervision	YES
6186262	30317393	LG	2	designed, supervised and provided technical expertise to the project|helped with some experiments	helped with some experiments	Performed the experiments	Investigation	YES
6186262	30317393	RZ	2	designed, supervised and provided technical expertise to the project|helped with some experiments	designed, supervised and provided technical expertise to the project	Conceived and designed the experiments	Methodology|Supervision	YES
6186262	30317393	RZ	2	designed, supervised and provided technical expertise to the project|helped with some experiments	helped with some experiments	Performed the experiments	Investigation	YES
6186262	30317393	Seed Funding	2	for this project was provided by the joseph nelson scholarship program from south dakota state university	for this project was provided by the joseph nelson scholarship program from south dakota state university	Analyzed the data	Formal analysis	YES
6186262	30317393	The authors	2	declare that they have no competing of interests	declare that they have no competing of interests	-	-	NO
6186262	30317393	WG	2	provided both scientific and funding support	provided both scientific and funding support	-	Funding acquisition	YES
2048577	17987126	AP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Patient recruitment, follow-up management	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2048577	17987126	AP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Patient recruitment, follow-up management	Performed the experiments	Performed the experiments	Investigation	YES
2048577	17987126	AP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Patient recruitment, follow-up management	Analyzed the data	Analyzed the data	Formal analysis	YES
2048577	17987126	AP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Patient recruitment, follow-up management	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2048577	17987126	AP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper|Patient recruitment, follow-up management	Patient recruitment, follow-up management	Performed the experiments	Investigation	YES
2048577	17987126	HL	PLoS5	Performed the experiments|Wrote the paper|Laboratory management	Performed the experiments	Performed the experiments	Investigation	YES
2048577	17987126	HL	PLoS5	Performed the experiments|Wrote the paper|Laboratory management	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2048577	17987126	HL	PLoS5	Performed the experiments|Wrote the paper|Laboratory management	Laboratory management	-	-	NO
2048577	17987126	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Patient recruitment, follow-up management	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2048577	17987126	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Patient recruitment, follow-up management	Performed the experiments	Performed the experiments	Investigation	YES
2048577	17987126	JS	PLoS5	Conceived and designed the experiments|Performed the experiments|Patient recruitment, follow-up management	Patient recruitment, follow-up management	Performed the experiments	Investigation	YES
2048577	17987126	WD	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2048577	17987126	WD	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2048577	17987126	WG	PLoS5	Performed the experiments|Laboratory assistant	Performed the experiments	Performed the experiments	Investigation	YES
2048577	17987126	WG	PLoS5	Performed the experiments|Laboratory assistant	Laboratory assistant	-	-	NO
2048577	17987126	XC	PLoS5	Performed the experiments|Patient recruitment, follow-up management	Performed the experiments	Performed the experiments	Investigation	YES
2048577	17987126	XC	PLoS5	Performed the experiments|Patient recruitment, follow-up management	Patient recruitment, follow-up management	Performed the experiments	Investigation	YES
2048577	17987126	XL	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2048577	17987126	XL	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2048577	17987126	XL	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2048577	17987126	XY	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2048577	17987126	XY	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2048577	17987126	XY	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2048577	17987126	XZ	PLoS5	Performed the experiments|Patient recruitment, follow-up management	Performed the experiments	Performed the experiments	Investigation	YES
2048577	17987126	XZ	PLoS5	Performed the experiments|Patient recruitment, follow-up management	Patient recruitment, follow-up management	Performed the experiments	Investigation	YES
2048577	17987126	YC	PLoS5	Performed the experiments|Analyzed the data|Dietary data analyses|Patient recruitment, follow-up management	Performed the experiments	Performed the experiments	Investigation	YES
2048577	17987126	YC	PLoS5	Performed the experiments|Analyzed the data|Dietary data analyses|Patient recruitment, follow-up management	Analyzed the data	Analyzed the data	Formal analysis	YES
2048577	17987126	YC	PLoS5	Performed the experiments|Analyzed the data|Dietary data analyses|Patient recruitment, follow-up management	Dietary data analyses	Analyzed the data	Formal analysis	YES
2048577	17987126	YC	PLoS5	Performed the experiments|Analyzed the data|Dietary data analyses|Patient recruitment, follow-up management	Patient recruitment, follow-up management	Performed the experiments	Investigation	YES
2048577	17987126	YL	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2048577	17987126	YL	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2048577	17987126	YW	PLoS5	Conceived and designed the experiments|Patient recruitment	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2048577	17987126	YW	PLoS5	Conceived and designed the experiments|Patient recruitment	Patient recruitment	Performed the experiments	Investigation	YES
2048577	17987126	ZY	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2048577	17987126	ZY	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2048577	17987126	ZY	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270948	25221866	BM	PLoS52	performed biological data	performed biological data	Performed the experiments	Investigation	YES
6270948	25221866	CC	PLoS52	designed research|performed research and analyzed the data|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
6270948	25221866	CC	PLoS52	designed research|performed research and analyzed the data|wrote the paper	performed research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270948	25221866	CC	PLoS52	designed research|performed research and analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270948	25221866	CS	PLoS52	performed cd spectra of compounds	performed cd spectra of compounds	Performed the experiments	Investigation	YES
6270948	25221866	GM	PLoS52	performed research and analyzed the data	performed research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270948	25221866	MAC	PLoS52	performed research and analyzed the data	performed research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270948	25221866	RR	PLoS52	designed research|performed research and analyzed the data|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
6270948	25221866	RR	PLoS52	designed research|performed research and analyzed the data|wrote the paper	performed research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270948	25221866	RR	PLoS52	designed research|performed research and analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270948	25221866	SVG	PLoS52	designed research|performed research and analyzed the data|wrote the paper	designed research	Conceived and designed the experiments	Methodology	YES
6270948	25221866	SVG	PLoS52	designed research|performed research and analyzed the data|wrote the paper	performed research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270948	25221866	SVG	PLoS52	designed research|performed research and analyzed the data|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6022441	29988327	CCh	2	helped analyze the data and write the manuscript	helped analyze the data and write the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6022441	29988327	CCl	2	helped analyze the data and write the manuscript	helped analyze the data and write the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6022441	29988327	CP	2	helped analyze the data and write the manuscript	helped analyze the data and write the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6022441	29988327	ED	2	helped analyze the data and write the manuscript	helped analyze the data and write the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6022441	29988327	FA	2	helped analyze the data and write the manuscript	helped analyze the data and write the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6022441	29988327	FB	2	helped analyze the data and write the manuscript	helped analyze the data and write the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6022441	29988327	GC	2	helped analyze the data and write the manuscript	helped analyze the data and write the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6022441	29988327	GL	2	helped analyze the data and write the manuscript	helped analyze the data and write the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6022441	29988327	GP	2	helped analyze the data and write the manuscript	helped analyze the data and write the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6022441	29988327	HW	2	helped analyze the data, write the manuscript, and perform the literature search	helped analyze the data, write the manuscript, and perform the literature search	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6022441	29988327	JCN	2	helped analyze the data and write the manuscript	helped analyze the data and write the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6022441	29988327	NB	2	helped analyze the data and write the manuscript	helped analyze the data and write the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5870212	29580211	CL	PLoS52	helped finalize the tables and figs	helped finalize the tables and figs	-	-	NO
5870212	29580211	CY	PLoS52	analyzed the rna seq data and drafted the manuscript	analyzed the rna seq data and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5870212	29580211	FQL	PLoS52	made extensive modification of the manuscript	made extensive modification of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5870212	29580211	LYJ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5870212	29580211	WW	PLoS52	designed the project|made extensive modification of the manuscript	designed the project	Conceived and designed the experiments	Methodology	YES
5870212	29580211	WW	PLoS52	designed the project|made extensive modification of the manuscript	made extensive modification of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5870212	29580211	XH	PLoS52	designed the project|made extensive modification of the manuscript	designed the project	Conceived and designed the experiments	Methodology	YES
5870212	29580211	XH	PLoS52	designed the project|made extensive modification of the manuscript	made extensive modification of the manuscript	Wrote the paper	Writing - Review & Editing	YES
5870212	29580211	ZYN	PLoS52	analyzed the rna seq data and drafted the manuscript|performed the experiments	analyzed the rna seq data and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5870212	29580211	ZYN	PLoS52	analyzed the rna seq data and drafted the manuscript|performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5859350	29593761	LC	2	wrote the manuscript|prepared the figures	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5859350	29593761	LC	2	wrote the manuscript|prepared the figures	prepared the figures	-	Visualization	YES
5859350	29593761	MM	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
5859350	29593761	PA	2	contributed to the writing of manuscript and critically revised it for essential intellectual content	contributed to the writing of manuscript and critically revised it for essential intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
5859350	29593761	SV	2	contributed to the writing of manuscript and critically revised it for essential intellectual content	contributed to the writing of manuscript and critically revised it for essential intellectual content	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
4420257	25942315	HO	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4420257	25942315	HO	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4420257	25942315	HO	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4420257	25942315	MK	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4420257	25942315	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4420257	25942315	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4420257	25942315	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4420257	25942315	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4420257	25942315	SM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4420257	25942315	TK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4420257	25942315	TK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4420257	25942315	TK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4420257	25942315	TK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4420257	25942315	TK	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4420257	25942315	TU	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4420257	25942315	YT	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5289302	28348417	AM	2	immunohistochemistry studies, data analysis, manuscript writing	immunohistochemistry studies, data analysis, manuscript writing	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5289302	28348417	IF	2	research design, data analysis, manuscript writing	research design, data analysis, manuscript writing	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5289302	28348417	MCG	2	data analysis, manuscript writing	data analysis, manuscript writing	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5289302	28348417	RF	2	research design, experiments performing, data analysis	research design, experiments performing, data analysis	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Investigation|Methodology	YES
6000141	29866917	All authors	2	contributed to the drafting of this manuscript	contributed to the drafting of this manuscript	Wrote the paper	Writing - Original Draft	YES
4720133	26641664	B.M.	2	contributed equally to this work	contributed equally to this work	-	-	NO
4720133	26641664	M.Z.C.	2	contributed equally to this work	contributed equally to this work	-	-	NO
5304266	28348419	AC	2	samples collection, experiments performing|manuscript writing	samples collection, experiments performing	Performed the experiments	Investigation	YES
5304266	28348419	AC	2	samples collection, experiments performing|manuscript writing	manuscript writing	Wrote the paper	Writing - Original Draft	YES
5304266	28348419	All authors	2	have edited, read and approved the final manuscript	have edited, read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5304266	28348419	BB	2	provided human oocytes	provided human oocytes	-	-	NO
5304266	28348419	CAR	2	study design|manuscript writing	study design	Conceived and designed the experiments	Methodology	YES
5304266	28348419	CAR	2	study design|manuscript writing	manuscript writing	Wrote the paper	Writing - Original Draft	YES
5304266	28348419	MM	2	study design|samples collection, experiments performing|manuscript writing	study design	Conceived and designed the experiments	Methodology	YES
5304266	28348419	MM	2	study design|samples collection, experiments performing|manuscript writing	samples collection, experiments performing	Performed the experiments	Investigation	YES
5304266	28348419	MM	2	study design|samples collection, experiments performing|manuscript writing	manuscript writing	Wrote the paper	Writing - Original Draft	YES
5304266	28348419	MW	2	provided human oocytes|samples collection, experiments performing	provided human oocytes	-	-	NO
5304266	28348419	MW	2	provided human oocytes|samples collection, experiments performing	samples collection, experiments performing	Performed the experiments	Investigation	YES
5304266	28348419	RRP	2	provided human oocytes	provided human oocytes	-	-	NO
2048661	18000538	AA	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2048661	18000538	AA	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2048661	18000538	AA	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2048661	18000538	IM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2048661	18000538	IM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2048661	18000538	IM	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2048661	18000538	JK	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2048661	18000538	JK	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2048661	18000538	JK	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2048661	18000538	LK	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2048661	18000538	LK	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2048661	18000538	LK	PLoS5	Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2048661	18000538	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2048661	18000538	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2048661	18000538	MC	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2048661	18000538	SM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2048661	18000538	SM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2048661	18000538	SM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2048661	18000538	SM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2048661	18000538	SR	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2048661	18000538	SR	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2048661	18000538	SR	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2048661	18000538	SR	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6032562	30002833	HO	PLoS52	analyzed the data|helped to draft the manuscript	analyzed the data	Analyzed the data	Formal analysis	YES
6032562	30002833	HO	PLoS52	analyzed the data|helped to draft the manuscript	helped to draft the manuscript	Wrote the paper	Writing - Original Draft	YES
6032562	30002833	HT	PLoS52	collected and generated the data|analyzed the data	collected and generated the data	Performed the experiments	Investigation	YES
6032562	30002833	HT	PLoS52	collected and generated the data|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
6032562	30002833	KJ	PLoS52	collected and generated the data	collected and generated the data	Performed the experiments	Investigation	YES
6032562	30002833	MO	PLoS52	collected and generated the data|analyzed the data	collected and generated the data	Performed the experiments	Investigation	YES
6032562	30002833	MO	PLoS52	collected and generated the data|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
6032562	30002833	TH	PLoS52	designed the study|collected and generated the data|wrote the first draft|analyzed the data	designed the study	Conceived and designed the experiments	Methodology	YES
6032562	30002833	TH	PLoS52	designed the study|collected and generated the data|wrote the first draft|analyzed the data	collected and generated the data	Performed the experiments	Investigation	YES
6032562	30002833	TH	PLoS52	designed the study|collected and generated the data|wrote the first draft|analyzed the data	wrote the first draft	Wrote the paper	Writing - Original Draft	YES
6032562	30002833	TH	PLoS52	designed the study|collected and generated the data|wrote the first draft|analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
6032562	30002833	TK	PLoS52	measured c1-inh activity values	measured c1-inh activity values	Performed the experiments	Investigation	YES
6032562	30002833	TS	PLoS52	helped to draft the manuscript	helped to draft the manuscript	Wrote the paper	Writing - Original Draft	YES
6032562	30002833	YN	PLoS52	collected and generated the data	collected and generated the data	Performed the experiments	Investigation	YES
6000145	29866922	A.A.	2	designed the study, collected and analysed the data, and wrote the manuscript	designed the study, collected and analysed the data, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
6000145	29866922	R.M.	2	designed the study, collected and analysed the data, and wrote the manuscript	designed the study, collected and analysed the data, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
3927954	24413189	AA	2	constructed plasmids	constructed plasmids	Performed the experiments	Investigation	YES
3927954	24413189	AM	2	constructed plasmids and assisted in clip experiment	constructed plasmids and assisted in clip experiment	Performed the experiments	Investigation	YES
3927954	24413189	AR	2	performed lars2 clip experiments and preparation of these samples for ion torrent sequencing	performed lars2 clip experiments and preparation of these samples for ion torrent sequencing	Performed the experiments	Investigation	YES
3927954	24413189	All authors	2	critically discussed results and approved final version of the manuscript	critically discussed results and approved final version of the manuscript	-	-	NO
3927954	24413189	DPA-K	2	generated and cloned the initial cybrid population and identified the respiratory deficient clones	generated and cloned the initial cybrid population and identified the respiratory deficient clones	Performed the experiments	Investigation	YES
3927954	24413189	HTHD	2	made substantive contributions to acquisition, presentation and analysis of data	made substantive contributions to acquisition, presentation and analysis of data	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
3927954	24413189	LF	2	made contributions to the design of the yeast research	made contributions to the design of the yeast research	Conceived and designed the experiments	Methodology	YES
3927954	24413189	RNL	2	were involved in hypothesis derivation, experimental design and execution, interpretation and funding project	were involved in hypothesis derivation, experimental design and execution, interpretation and funding project	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Funding acquisition|Investigation|Methodology	YES
3927954	24413189	SF	2	made contributions to the design of the yeast research|studied the c-terminal domain sequences to be cloned	made contributions to the design of the yeast research	Conceived and designed the experiments	Methodology	YES
3927954	24413189	SF	2	made contributions to the design of the yeast research|studied the c-terminal domain sequences to be cloned	studied the c-terminal domain sequences to be cloned	Performed the experiments	Investigation	YES
3927954	24413189	ZCL	2	were involved in hypothesis derivation, experimental design and execution, interpretation and funding project	were involved in hypothesis derivation, experimental design and execution, interpretation and funding project	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Formal analysis|Funding acquisition|Investigation|Methodology	YES
4420259	25942318	DP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4420259	25942318	DP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4420259	25942318	DP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4420259	25942318	DP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4420259	25942318	MT	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4420259	25942318	MT	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4420259	25942318	TM	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
3914411	24558317	Wei Zhang	2	are cofirst authors contributing equally to this study	are cofirst authors contributing equally to this study	-	-	NO
3914411	24558317	Yi-Zhi Xu	2	are cofirst authors contributing equally to this study	are cofirst authors contributing equally to this study	-	-	NO
5870257	29580224	AK	2	interpreted the data|edited and revised the manuscript	interpreted the data	Analyzed the data	Formal analysis	YES
5870257	29580224	AK	2	interpreted the data|edited and revised the manuscript	edited and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5870257	29580224	EJV	2	genotyped and validated the homokaryotic isolates|edited and revised the manuscript	genotyped and validated the homokaryotic isolates	Performed the experiments	Investigation|Validation	YES
5870257	29580224	EJV	2	genotyped and validated the homokaryotic isolates|edited and revised the manuscript	edited and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5870257	29580224	EM	2	contributed to the data analysis	contributed to the data analysis	Analyzed the data	Formal analysis	YES
5870257	29580224	FOA	2	conceived the study|designed the experiment and interpreted the data|edited and revised the manuscript	conceived the study	Conceived and designed the experiments	Conceptualization	YES
5870257	29580224	FOA	2	conceived the study|designed the experiment and interpreted the data|edited and revised the manuscript	designed the experiment and interpreted the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5870257	29580224	FOA	2	conceived the study|designed the experiment and interpreted the data|edited and revised the manuscript	edited and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5870257	29580224	HS	2	conducted the single spore isolation and generated the homokaryotic isolates|edited and revised the manuscript	conducted the single spore isolation and generated the homokaryotic isolates	Performed the experiments	Investigation	YES
5870257	29580224	HS	2	conducted the single spore isolation and generated the homokaryotic isolates|edited and revised the manuscript	edited and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5870257	29580224	SD	2	contributed to the data analysis|edited and revised the manuscript	contributed to the data analysis	Analyzed the data	Formal analysis	YES
5870257	29580224	SD	2	contributed to the data analysis|edited and revised the manuscript	edited and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5870257	29580224	TR	2	interpreted the data|edited and revised the manuscript	interpreted the data	Analyzed the data	Formal analysis	YES
5870257	29580224	TR	2	interpreted the data|edited and revised the manuscript	edited and revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5870257	29580224	ZZ	2	designed the experiment and interpreted the data|performed the experiment, analyzed the data and wrote the manuscript	designed the experiment and interpreted the data	Conceived and designed the experiments|Analyzed the data	Formal analysis|Methodology	YES
5870257	29580224	ZZ	2	designed the experiment and interpreted the data|performed the experiment, analyzed the data and wrote the manuscript	performed the experiment, analyzed the data and wrote the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6042359	30009033	NS	2	supervised the study and revised the manuscript	supervised the study and revised the manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
6042359	30009033	ON	2	designed and organized the study, helped with data collection, and revised the manuscript	designed and organized the study, helped with data collection, and revised the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Project administration|Writing - Review & Editing	YES
6042359	30009033	SN	2	designed and organized the study, helped with data collection, and revised the manuscript	designed and organized the study, helped with data collection, and revised the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Project administration|Writing - Review & Editing	YES
6042359	30009033	SO	2	collected and analyzed the data and drafted the manuscript	collected and analyzed the data and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6042359	30009033	ST	2	designed and organized the study, helped with data collection, and revised the manuscript	designed and organized the study, helped with data collection, and revised the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Project administration|Writing - Review & Editing	YES
5859377	29593757	All authors	2	reviewed and edited the manuscript	reviewed and edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5859377	29593757	BF	2	shaped the research concept and guided and supervised experiments	shaped the research concept and guided and supervised experiments	Conceived and designed the experiments	Conceptualization|Supervision	YES
5859377	29593757	FO	2	developed the research concept, conducted the experiments, collected and analyzed the data, and wrote the manuscript	developed the research concept, conducted the experiments, collected and analyzed the data, and wrote the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Writing - Original Draft	YES
5859377	29593757	GT	2	shaped the research concept and guided and supervised the experiments	shaped the research concept and guided and supervised the experiments	Conceived and designed the experiments	Conceptualization|Supervision	YES
5859377	29593757	IS	2	shaped the research concept and guided and supervised experiments	shaped the research concept and guided and supervised experiments	Conceived and designed the experiments	Conceptualization|Supervision	YES
5859377	29593757	JT	2	supported gene expression assay and microscopy	supported gene expression assay and microscopy	Performed the experiments	Investigation	YES
5859377	29593757	L-HC	2	supported vector design, gene cloning, and transformation of fungi	supported vector design, gene cloning, and transformation of fungi	Conceived and designed the experiments|Performed the experiments	Investigation	YES
5859377	29593757	LT	2	shaped the research concept, guided and supervised the experiments, and wrote the manuscript	shaped the research concept, guided and supervised the experiments, and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Supervision|Writing - Original Draft	YES
6188973	30324529	All authors	PLoS52	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6188973	30324529	BH	PLoS52	conceived and designed the experiments|wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6188973	30324529	BH	PLoS52	conceived and designed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6188973	30324529	BZ	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6188973	30324529	CO	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6188973	30324529	CZ	PLoS52	contributed reagents/materials/analysis tools	contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
6188973	30324529	HL	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
6188973	30324529	JW	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
6188973	30324529	LF	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
6188973	30324529	LL	PLoS52	analyzed the data	analyzed the data	Analyzed the data	Formal analysis	YES
6188973	30324529	QW	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
6188973	30324529	WT	PLoS52	conceived and designed the experiments	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5304267	28348423	AC	2	study execution	study execution	Performed the experiments	Investigation	YES
5304267	28348423	AM	2	study execution	study execution	Performed the experiments	Investigation	YES
5304267	28348423	AMC	2	study planning and execution, results analysis and manuscript preparation	study planning and execution, results analysis and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5304267	28348423	AP	2	study execution	study execution	Performed the experiments	Investigation	YES
5304267	28348423	AR	2	study execution	study execution	Performed the experiments	Investigation	YES
5304267	28348423	CC	2	study planning, manuscript preparation	study planning, manuscript preparation	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5304267	28348423	CP	2	study planning and execution, results analysis and manuscript preparation	study planning and execution, results analysis and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
5304267	28348423	FL	2	interpretation of data	interpretation of data	Analyzed the data	Formal analysis	YES
5304267	28348423	FP	2	interpretation of data	interpretation of data	Analyzed the data	Formal analysis	YES
5304267	28348423	GP	2	study planning, manuscript preparation	study planning, manuscript preparation	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Original Draft	YES
5304267	28348423	PC	2	interpretation of data	interpretation of data	Analyzed the data	Formal analysis	YES
2048662	18000543	BS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2048662	18000543	BS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2048662	18000543	BS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2048662	18000543	BS	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2048662	18000543	CM	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
2048662	18000543	CM	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2048662	18000543	HS	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
2048662	18000543	HS	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2048662	18000543	JJ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
2048662	18000543	JJ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
2048662	18000543	JJ	PLoS5	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2048662	18000543	LS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Played a key role by providing expertise in host immune responses to pathogens, analyzing flow cytometry data, and aiding in experimental design	Analyzed the data	Analyzed the data	Formal analysis	YES
2048662	18000543	LS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Played a key role by providing expertise in host immune responses to pathogens, analyzing flow cytometry data, and aiding in experimental design	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2048662	18000543	LS	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Played a key role by providing expertise in host immune responses to pathogens, analyzing flow cytometry data, and aiding in experimental design	Played a key role by providing expertise in host immune responses to pathogens, analyzing flow cytometry data, and aiding in experimental design	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Methodology|Resources	YES
2048662	18000543	SH	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Head of the lab|Played a central role by providing expertise in design, performance, and analysis of experiments and the preparation of the manuscript	Analyzed the data	Analyzed the data	Formal analysis	YES
2048662	18000543	SH	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Head of the lab|Played a central role by providing expertise in design, performance, and analysis of experiments and the preparation of the manuscript	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2048662	18000543	SH	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Head of the lab|Played a central role by providing expertise in design, performance, and analysis of experiments and the preparation of the manuscript	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2048662	18000543	SH	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Head of the lab|Played a central role by providing expertise in design, performance, and analysis of experiments and the preparation of the manuscript	Head of the lab	-	-	NO
2048662	18000543	SH	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper|Head of the lab|Played a central role by providing expertise in design, performance, and analysis of experiments and the preparation of the manuscript	Played a central role by providing expertise in design, performance, and analysis of experiments and the preparation of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft	YES
6270949	25490431	Anna Aiello	7	review of the manuscript; Maria Senese and Filomena	review of the manuscript; Maria Senese and Filomena	Wrote the paper	Writing - Review & Editing	YES
6270949	25490431	Concetta Imperatore	7	data collection, manuscript preparation, and review of the manuscript	data collection, manuscript preparation, and review of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft|Writing - Review & Editing	YES
6270949	25490431	DAniello	7	data collection	data collection	Performed the experiments	Investigation	YES
6270949	25490431	Marialuisa Menna	7	conception, manuscript preparation, and review of the manuscript	conception, manuscript preparation, and review of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft|Writing - Review & Editing	YES
5870336	29587637	HX	PLoS52	conceived and designed the experiments|revised the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5870336	29587637	HX	PLoS52	conceived and designed the experiments|revised the paper	revised the paper	Wrote the paper	Writing - Review & Editing	YES
5870336	29587637	JMZ	PLoS52	conceived and designed the experiments|revised the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5870336	29587637	JMZ	PLoS52	conceived and designed the experiments|revised the paper	revised the paper	Wrote the paper	Writing - Review & Editing	YES
5870336	29587637	NG	PLoS52	conducted the molecular experiments and collected samples	conducted the molecular experiments and collected samples	Performed the experiments	Investigation	YES
5870336	29587637	WBW	PLoS52	conducted the molecular experiments and collected samples	conducted the molecular experiments and collected samples	Performed the experiments	Investigation	YES
5870336	29587637	XLZ	PLoS52	performed the experiments and analyzed the data|conducted the molecular experiments and collected samples|wrote the paper|revised the paper	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5870336	29587637	XLZ	PLoS52	performed the experiments and analyzed the data|conducted the molecular experiments and collected samples|wrote the paper|revised the paper	conducted the molecular experiments and collected samples	Performed the experiments	Investigation	YES
5870336	29587637	XLZ	PLoS52	performed the experiments and analyzed the data|conducted the molecular experiments and collected samples|wrote the paper|revised the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5870336	29587637	XLZ	PLoS52	performed the experiments and analyzed the data|conducted the molecular experiments and collected samples|wrote the paper|revised the paper	revised the paper	Wrote the paper	Writing - Review & Editing	YES
5870336	29587637	YPB	PLoS52	conducted the molecular experiments and collected samples	conducted the molecular experiments and collected samples	Performed the experiments	Investigation	YES
5870336	29587637	YYZ	PLoS52	conducted the molecular experiments and collected samples	conducted the molecular experiments and collected samples	Performed the experiments	Investigation	YES
4420260	25942409	HC	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4420260	25942409	HC	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4420260	25942409	JN	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4420260	25942409	JN	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4420260	25942409	MAG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4420260	25942409	MAG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4420260	25942409	MAG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4420260	25942409	MAG	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4420260	25942409	MAH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4420260	25942409	MAH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4420260	25942409	MAH	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4420260	25942409	MRP	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4420260	25942409	MRP	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4420260	25942409	RLH	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4420260	25942409	SR	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4420260	25942409	SR	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4420260	25942409	TRK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4420260	25942409	TRK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4420260	25942409	TRK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4420260	25942409	TRK	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6050674	30026951	YK	2	wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3927955	24150896	AP	2	performed the egfp-dsred-co-trasduction experiments	performed the egfp-dsred-co-trasduction experiments	Performed the experiments	Investigation	YES
3927955	24150896	AS	2	performed retinal histology and contributed to the generation of plasmid constructs	performed retinal histology and contributed to the generation of plasmid constructs	Performed the experiments	Investigation	YES
3927955	24150896	CI	2	performed retinal histology and contributed to the generation of plasmid constructs|performed subretinal injections in mice	performed retinal histology and contributed to the generation of plasmid constructs	Performed the experiments	Investigation	YES
3927955	24150896	CI	2	performed retinal histology and contributed to the generation of plasmid constructs|performed subretinal injections in mice	performed subretinal injections in mice	Performed the experiments	Investigation	YES
3927955	24150896	EM	2	performed the electrophysiological recordings and helped with work in pigs	performed the electrophysiological recordings and helped with work in pigs	Performed the experiments	Investigation	YES
3927955	24150896	GC	2	performed retinal histology and contributed to the generation of plasmid constructs	performed retinal histology and contributed to the generation of plasmid constructs	Performed the experiments	Investigation	YES
3927955	24150896	GJF	2	performed the egfp-dsred-co-trasduction experiments	performed the egfp-dsred-co-trasduction experiments	Performed the experiments	Investigation	YES
3927955	24150896	MG	2	performed anesthesia in pigs	performed anesthesia in pigs	Performed the experiments	Investigation	YES
3927955	24150896	RP	2	performed immune-electron microscopy analyzes	performed immune-electron microscopy analyzes	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3927955	24150896	SR	2	performed subretinal injections in pigs	performed subretinal injections in pigs	Performed the experiments	Investigation	YES
3927955	24150896	SdS	2	performed retinal histology and contributed to the generation of plasmid constructs	performed retinal histology and contributed to the generation of plasmid constructs	Performed the experiments	Investigation	YES
5861152	29593773	BS	2	performed the next-generation sequencing experiments	performed the next-generation sequencing experiments	Performed the experiments	Investigation	YES
5861152	29593773	DY	2	performed the pcr experiments	performed the pcr experiments	Performed the experiments	Investigation	YES
5861152	29593773	HC	2	performed data analysis and wrote the manuscript	performed data analysis and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
5861152	29593773	HZ	2	performed the pcr experiments	performed the pcr experiments	Performed the experiments	Investigation	YES
5861152	29593773	JS	2	extracted dna	extracted dna	Performed the experiments	Investigation	YES
5861152	29593773	LH	2	identified the plant material	identified the plant material	Performed the experiments	Investigation	YES
5861152	29593773	MH	2	performed the next-generation sequencing experiments	performed the next-generation sequencing experiments	Performed the experiments	Investigation	YES
5861152	29593773	MJ	2	performed the pcr experiments	performed the pcr experiments	Performed the experiments	Investigation	YES
5861152	29593773	MR	2	performed the next-generation sequencing experiments	performed the next-generation sequencing experiments	Performed the experiments	Investigation	YES
5861152	29593773	XL	2	performed the next-generation sequencing experiments	performed the next-generation sequencing experiments	Performed the experiments	Investigation	YES
5861152	29593773	ZZ	2	identified the plant material	identified the plant material	Performed the experiments	Investigation	YES
4420262	25942319	CL	PLoS5	Wrote the paper|Conceived and designed the study|Collected the data	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4420262	25942319	CL	PLoS5	Wrote the paper|Conceived and designed the study|Collected the data	Conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4420262	25942319	CL	PLoS5	Wrote the paper|Conceived and designed the study|Collected the data	Collected the data	Performed the experiments	Investigation	YES
4420262	25942319	DK	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4420262	25942319	JG	PLoS5	Wrote the paper|Conceived and designed the study|Collected the data	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4420262	25942319	JG	PLoS5	Wrote the paper|Conceived and designed the study|Collected the data	Conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4420262	25942319	JG	PLoS5	Wrote the paper|Conceived and designed the study|Collected the data	Collected the data	Performed the experiments	Investigation	YES
4420262	25942319	MS	PLoS5	Analyzed the data|Wrote the paper|Conceived and designed the study|Collected the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4420262	25942319	MS	PLoS5	Analyzed the data|Wrote the paper|Conceived and designed the study|Collected the data	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4420262	25942319	MS	PLoS5	Analyzed the data|Wrote the paper|Conceived and designed the study|Collected the data	Conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4420262	25942319	MS	PLoS5	Analyzed the data|Wrote the paper|Conceived and designed the study|Collected the data	Collected the data	Performed the experiments	Investigation	YES
4420262	25942319	SK	PLoS5	Analyzed the data|Wrote the paper|Conceived and designed the study|Collected the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4420262	25942319	SK	PLoS5	Analyzed the data|Wrote the paper|Conceived and designed the study|Collected the data	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4420262	25942319	SK	PLoS5	Analyzed the data|Wrote the paper|Conceived and designed the study|Collected the data	Conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
4420262	25942319	SK	PLoS5	Analyzed the data|Wrote the paper|Conceived and designed the study|Collected the data	Collected the data	Performed the experiments	Investigation	YES
5870388	29587632	HL	PLoS52	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5870388	29587632	LY	PLoS52	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5870388	29587632	LZ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5870388	29587632	MNA	PLoS52	designed the experiments|performed the experiments|wrote the paper	designed the experiments	Conceived and designed the experiments	Methodology	YES
5870388	29587632	MNA	PLoS52	designed the experiments|performed the experiments|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5870388	29587632	MNA	PLoS52	designed the experiments|performed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5870388	29587632	MRI	PLoS52	revised the manuscript	revised the manuscript	Wrote the paper	Writing - Review & Editing	YES
5870388	29587632	PY	PLoS52	interpreted the data for the work	interpreted the data for the work	Analyzed the data	Formal analysis	YES
5870388	29587632	QW	PLoS52	designed the experiments|wrote the paper	designed the experiments	Conceived and designed the experiments	Methodology	YES
5870388	29587632	QW	PLoS52	designed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
5870388	29587632	YL	PLoS52	interpreted the data for the work	interpreted the data for the work	Analyzed the data	Formal analysis	YES
5870388	29587632	ZC	PLoS52	designed the experiments|performed the experiments|wrote the paper	designed the experiments	Conceived and designed the experiments	Methodology	YES
5870388	29587632	ZC	PLoS52	designed the experiments|performed the experiments|wrote the paper	performed the experiments	Performed the experiments	Investigation	YES
5870388	29587632	ZC	PLoS52	designed the experiments|performed the experiments|wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270950	25407718	JW	PLoS52	performed research and analyzed the data	performed research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270950	25407718	MG	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270950	25407718	PZ	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270950	25407718	RL	PLoS52	performed research and analyzed the data	performed research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270950	25407718	RW	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270950	25407718	SL	PLoS52	wrote the paper	wrote the paper	Wrote the paper	Writing - Original Draft	YES
6270950	25407718	XH	PLoS52	performed research and analyzed the data	performed research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270950	25407718	XM	PLoS52	performed research and analyzed the data	performed research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270950	25407718	XX	PLoS52	designed research	designed research	Conceived and designed the experiments	Methodology	YES
6270950	25407718	YH	PLoS52	performed research and analyzed the data	performed research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270950	25407718	YZ	PLoS52	designed research	designed research	Conceived and designed the experiments	Methodology	YES
5327749	28348422	FN	2	data acquisition	data acquisition	Performed the experiments	Investigation	YES
5327749	28348422	KH	2	study concept and design, data analysis and interpretation|data acquisition|manuscript drafting	study concept and design, data analysis and interpretation	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
5327749	28348422	KH	2	study concept and design, data analysis and interpretation|data acquisition|manuscript drafting	data acquisition	Performed the experiments	Investigation	YES
5327749	28348422	KH	2	study concept and design, data analysis and interpretation|data acquisition|manuscript drafting	manuscript drafting	Wrote the paper	Writing - Original Draft	YES
5327749	28348422	MA	2	study concept and design, data analysis and interpretation|manuscript drafting	study concept and design, data analysis and interpretation	Conceived and designed the experiments|Analyzed the data	Conceptualization|Formal analysis|Methodology	YES
5327749	28348422	MA	2	study concept and design, data analysis and interpretation|manuscript drafting	manuscript drafting	Wrote the paper	Writing - Original Draft	YES
5327749	28348422	RK	2	manuscript drafting	manuscript drafting	Wrote the paper	Writing - Original Draft	YES
5327749	28348422	YO	2	data acquisition	data acquisition	Performed the experiments	Investigation	YES
2048663	18000551	CD	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2048663	18000551	JB	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
2048663	18000551	MB	PLoS5	Conceived and designed the experiments|Performed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2048663	18000551	MB	PLoS5	Conceived and designed the experiments|Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
2048663	18000551	PR	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
2048663	18000551	PS	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2048663	18000551	SW	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
6056934	30062013	DS	2	treated the patient and wrote the manuscript	treated the patient and wrote the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6056934	30062013	DW	2	treated the patient, contributed fig	treated the patient, contributed fig	Performed the experiments	Investigation|Visualization	YES
6056934	30062013	MH	2	treated the patient and edited the manuscript	treated the patient and edited the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
6056934	30062013	MM	2	treated the patient and edited the manuscript	treated the patient and edited the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
6056934	30062013	MX	2	treated the patient, contributed fig	treated the patient, contributed fig	Performed the experiments	Investigation|Visualization	YES
6056934	30062013	RS	2	treated the patient, contributed fig	treated the patient, contributed fig	Performed the experiments	Investigation|Visualization	YES
6188974	30324223	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6188974	30324223	BJ	2	assisted in pcr work	assisted in pcr work	Performed the experiments	Investigation	YES
6188974	30324223	KNS	2	are collaborators of the project	are collaborators of the project	-	-	NO
6188974	30324223	OTP	2	are collaborators of the project	are collaborators of the project	-	-	NO
6188974	30324223	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
4420263	25942021	AP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4420263	25942021	DL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4420263	25942021	DL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4420263	25942021	DL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4420263	25942021	DL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4420263	25942021	GS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4420263	25942021	GS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
4420263	25942021	GS	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4420263	25942021	ML	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4420263	25942021	PR	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Performed the experiments	Performed the experiments	Investigation	YES
4420263	25942021	PR	PLoS5	Performed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
3927956	24401838	AB	2	conceived and designed experiments|supervised the work	conceived and designed experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
3927956	24401838	AB	2	conceived and designed experiments|supervised the work	supervised the work	-	Supervision	YES
3927956	24401838	CP	2	designed vectors and performed embryonic stem cell manipulation	designed vectors and performed embryonic stem cell manipulation	Conceived and designed the experiments|Performed the experiments	Investigation	YES
3927956	24401838	EMM	2	acquired technology	acquired technology	-	-	NO
3927956	24401838	HdV	2	established primary mesothelioma cultures	established primary mesothelioma cultures	Performed the experiments	Investigation	YES
3927956	24401838	IJH	2	conceived and designed experiments, performed project coordination, data analysis and wrote the paper	conceived and designed experiments, performed project coordination, data analysis and wrote the paper	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Project administration|Writing - Original Draft	YES
3927956	24401838	JB	2	provided cohorts for conventional mesothelioma and lung tumor groups, respectively	provided cohorts for conventional mesothelioma and lung tumor groups, respectively	-	-	NO
3927956	24401838	JJ	2	conceived and designed experiments|supervised the work	conceived and designed experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
3927956	24401838	JJ	2	conceived and designed experiments|supervised the work	supervised the work	-	Supervision	YES
3927956	24401838	JYS	2	analyzed tumors	analyzed tumors	Analyzed the data	Formal analysis	YES
3927956	24401838	KS	2	provided cohorts for conventional mesothelioma and lung tumor groups, respectively	provided cohorts for conventional mesothelioma and lung tumor groups, respectively	-	-	NO
3927956	24401838	MC	2	performed health monitoring of mice, viral intubations and luciferase imaging	performed health monitoring of mice, viral intubations and luciferase imaging	Performed the experiments|Analyzed the data	Investigation|Supervision|Visualization	YES
3927956	24401838	MCK	2	performed mycl1 copy number analysis	performed mycl1 copy number analysis	Performed the experiments	Investigation	YES
3927956	24401838	NP	2	performed health monitoring of mice, viral intubations and luciferase imaging	performed health monitoring of mice, viral intubations and luciferase imaging	Performed the experiments|Analyzed the data	Investigation|Supervision|Visualization	YES
3927956	24401838	PK	2	conceived and designed experiments	conceived and designed experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
3927956	24401838	RBA	2	performed esc derivations and injections	performed esc derivations and injections	Performed the experiments	Investigation	YES
5870497	29580210	B.R.H.	2	prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5870497	29580210	C.J.F.	2	who also developed analysis pipelines for wgbs data	who also developed analysis pipelines for wgbs data	Analyzed the data	Formal analysis	YES
5870497	29580210	G.E.R.	2	jointly conceived the study and designed the experiments|prepared the manuscript	jointly conceived the study and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5870497	29580210	G.E.R.	2	jointly conceived the study and designed the experiments|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
5870497	29580210	M.S.S.	2	jointly conceived the study and designed the experiments|performed behavioral assays and prepared biological samples|who also developed analysis pipelines for wgbs data|prepared the manuscript	jointly conceived the study and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5870497	29580210	M.S.S.	2	jointly conceived the study and designed the experiments|performed behavioral assays and prepared biological samples|who also developed analysis pipelines for wgbs data|prepared the manuscript	performed behavioral assays and prepared biological samples	Performed the experiments	Investigation	YES
5870497	29580210	M.S.S.	2	jointly conceived the study and designed the experiments|performed behavioral assays and prepared biological samples|who also developed analysis pipelines for wgbs data|prepared the manuscript	who also developed analysis pipelines for wgbs data	Analyzed the data	Formal analysis	YES
5870497	29580210	M.S.S.	2	jointly conceived the study and designed the experiments|performed behavioral assays and prepared biological samples|who also developed analysis pipelines for wgbs data|prepared the manuscript	prepared the manuscript	Wrote the paper	Writing - Original Draft	YES
6064044	30065843	JO	2	undertook the critical revision of the manuscript	undertook the critical revision of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Review & Editing	YES
6064044	30065843	NN	2	equally managed the patient	equally managed the patient	Performed the experiments	Investigation	YES
6064044	30065843	TI	2	was a major contributor in the analysis of data and manuscript preparation	was a major contributor in the analysis of data and manuscript preparation	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Formal analysis|Resources|Writing - Original Draft	YES
6064044	30065843	YU	2	equally managed the patient	equally managed the patient	Performed the experiments	Investigation	YES
2048664	18000550	BZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
2048664	18000550	DL	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
2048664	18000550	JC	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
2048664	18000550	JH	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2048664	18000550	JH	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2048664	18000550	JL	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
2048664	18000550	JL	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2048664	18000550	XA	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
2048664	18000550	XA	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2048664	18000550	XZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
2048664	18000550	YT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2048664	18000550	YT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2048664	18000550	YT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2048664	18000550	YT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2048664	18000550	YT	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2048664	18000550	YZ	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
5364978	28348424	AP	2	visited animals and collected samples	visited animals and collected samples	Performed the experiments	Investigation	YES
5364978	28348424	AT	2	visited animals and collected samples	visited animals and collected samples	Performed the experiments	Investigation	YES
5364978	28348424	CDA	2	immunohistochemical studies|work supervision	immunohistochemical studies	Performed the experiments	Investigation	YES
5364978	28348424	CDA	2	immunohistochemical studies|work supervision	work supervision	-	Supervision	YES
5364978	28348424	CP	2	manuscript drafting	manuscript drafting	Wrote the paper	Writing - Original Draft	YES
5364978	28348424	FM	2	manuscript revision	manuscript revision	Wrote the paper	Writing - Review & Editing	YES
5364978	28348424	MGC	2	manuscript drafting	manuscript drafting	Wrote the paper	Writing - Original Draft	YES
5364978	28348424	MM	2	immunohistochemical studies	immunohistochemical studies	Performed the experiments	Investigation	YES
5364978	28348424	PS	2	manuscript revision	manuscript revision	Wrote the paper	Writing - Review & Editing	YES
6270951	25347459	JMS	2	both contributed equally to writing this article|both conducted literature searches, interpreted findings, wrote text, edited, and revised the manuscript	both contributed equally to writing this article	Wrote the paper	Writing - Original Draft	YES
6270951	25347459	JMS	2	both contributed equally to writing this article|both conducted literature searches, interpreted findings, wrote text, edited, and revised the manuscript	both conducted literature searches, interpreted findings, wrote text, edited, and revised the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
6270951	25347459	OLB	2	both contributed equally to writing this article|both conducted literature searches, interpreted findings, wrote text, edited, and revised the manuscript	both contributed equally to writing this article	Wrote the paper	Writing - Original Draft	YES
6270951	25347459	OLB	2	both contributed equally to writing this article|both conducted literature searches, interpreted findings, wrote text, edited, and revised the manuscript	both conducted literature searches, interpreted findings, wrote text, edited, and revised the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft|Writing - Review & Editing	YES
6015838	29915007	A.M.	2	contributed to the study conception and design|collected and coded jahai data|conducted analyses and drafted the article	contributed to the study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6015838	29915007	A.M.	2	contributed to the study conception and design|collected and coded jahai data|conducted analyses and drafted the article	collected and coded jahai data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
6015838	29915007	A.M.	2	contributed to the study conception and design|collected and coded jahai data|conducted analyses and drafted the article	conducted analyses and drafted the article	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6015838	29915007	All authors	2	provided comments on manuscript, and approved the final version	provided comments on manuscript, and approved the final version	-	-	NO
6015838	29915007	B.S.H.	2	contributed to the study conception and design	contributed to the study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6015838	29915007	J.d.V.	2	coded facial expressions and contributed to dutch language coding	coded facial expressions and contributed to dutch language coding	Performed the experiments	Investigation	YES
6015838	29915007	M.S.	2	contributed to the study conception and design	contributed to the study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6015838	29915007	N.B.	2	contributed to the study conception and design|collected and coded jahai data	contributed to the study conception and design	Conceived and designed the experiments	Conceptualization|Methodology	YES
6015838	29915007	N.B.	2	contributed to the study conception and design|collected and coded jahai data	collected and coded jahai data	Performed the experiments|Analyzed the data	Data curation|Investigation	YES
4420265	25942434	JHKL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4420265	25942434	JHKL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4420265	25942434	JHKL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4420265	25942434	JHKL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4420265	25942434	JHKL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4420265	25942434	KM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4420265	25942434	KM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4420265	25942434	KM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4420265	25942434	KM	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4420265	25942434	RNW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4420265	25942434	RNW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4420265	25942434	RNW	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
3927957	24399752	CJK	2	designed experiments, provided reagents and corrected the manuscript	designed experiments, provided reagents and corrected the manuscript	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Methodology|Resources|Writing - Review & Editing	YES
3927957	24399752	CM	2	performed histology	performed histology	Performed the experiments	Investigation	YES
3927957	24399752	JJ	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
3927957	24399752	MB	2	designed and performed experiments, wrote the manuscript and supervised the project	designed and performed experiments, wrote the manuscript and supervised the project	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Supervision|Writing - Original Draft	YES
3927957	24399752	MG	2	designed the experiments, supervised the project and refined the manuscript	designed the experiments, supervised the project and refined the manuscript	Conceived and designed the experiments	Methodology|Supervision	YES
3927957	24399752	SM	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
3927957	24399752	TM	2	performed experiments	performed experiments	Performed the experiments	Investigation	YES
5861201	29593772	DC	2	designed the research	designed the research	Conceived and designed the experiments	Methodology	YES
5861201	29593772	VC	2	designed the research|conducted the research and analyzed the data	designed the research	Conceived and designed the experiments	Methodology	YES
5861201	29593772	VC	2	designed the research|conducted the research and analyzed the data	conducted the research and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6191402	30328017	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6191402	30328017	IT	2	performed the experiments and drafted the manuscript	performed the experiments and drafted the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6191402	30328017	KP	2	supervised the whole project and revised the manuscript	supervised the whole project and revised the manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
6191402	30328017	PM	2	supervised cell culture experiments	supervised cell culture experiments	Performed the experiments	Investigation|Supervision	YES
6191402	30328017	Pharmacological Laboratory	2	university of brawijaya, indonesia, with approval from the ethics committee for animal experimentation at the university of brawijaya	university of brawijaya, indonesia, with approval from the ethics committee for animal experimentation at the university of brawijaya	Performed the experiments	Investigation	YES
6191402	30328017	SA	2	supervised statistical design and analysis	supervised statistical design and analysis	Conceived and designed the experiments|Analyzed the data	Formal analysis|Supervision	YES
6191402	30328017	SR	2	initiated hypertension vaccine project and gave comments on manuscript	initiated hypertension vaccine project and gave comments on manuscript	Conceived and designed the experiments	Conceptualization	YES
6191402	30328017	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
2048665	18000544	Nv Mv	PLoS5	Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6064183	30065844	AAA	2	contributed to data acquisition and drafting of parts of the manuscript	contributed to data acquisition and drafting of parts of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6064183	30065844	All authors	2	had full access to the data	had full access to the data	-	-	NO
6064183	30065844	FA	2	takes responsibility for the integrity of the data and accuracy of the data analysis|contributed to the conception, design, and drafting of the manuscript	takes responsibility for the integrity of the data and accuracy of the data analysis	Analyzed the data	Data curation|Formal analysis	YES
6064183	30065844	FA	2	takes responsibility for the integrity of the data and accuracy of the data analysis|contributed to the conception, design, and drafting of the manuscript	contributed to the conception, design, and drafting of the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Writing - Original Draft	YES
6064183	30065844	JD	2	contributed to the final design, creation, and authorship of this manuscript	contributed to the final design, creation, and authorship of this manuscript	Conceived and designed the experiments	-	YES
6064183	30065844	RK	2	contributed to data acquisition and drafting of parts of the manuscript	contributed to data acquisition and drafting of parts of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6064183	30065844	YL	2	contributed to analysis and interpretation	contributed to analysis and interpretation	Analyzed the data	Formal analysis	YES
5870498	29587634	BKD	2	performed sequence alignments and compared data between libraries	performed sequence alignments and compared data between libraries	Performed the experiments	Investigation	YES
5870498	29587634	CS	2	performed preliminary sequence alignments	performed preliminary sequence alignments	Performed the experiments	Investigation	YES
5870498	29587634	EEG	2	grew the bacteria, extracted and prepared the rna, performed data analysis, coordinated the project with fslb and drafted the manuscript	grew the bacteria, extracted and prepared the rna, performed data analysis, coordinated the project with fslb and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Project administration|Writing - Original Draft	YES
5870498	29587634	FSLB	2	supervised the project and edited the manuscript	supervised the project and edited the manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
5870498	29587634	GLW	2	performed analysis of the transcription start site data and implemented tools to visualize all sequencing data	performed analysis of the transcription start site data and implemented tools to visualize all sequencing data	Performed the experiments|Analyzed the data	Formal analysis|Investigation|Visualization	YES
5870498	29587634	LSC	2	performed analysis of the cleavage site and transcription start site data	performed analysis of the cleavage site and transcription start site data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5870498	29587634	ND	2	implemented the prna seq protocol and prepared rna for prna seq	implemented the prna seq protocol and prepared rna for prna seq	Conceived and designed the experiments|Performed the experiments	Investigation|Methodology	YES
5870498	29587634	PJU	2	supervised the project and edited the manuscript	supervised the project and edited the manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
5870498	29587634	PKT	2	grew bacteria, extracted rna, conducted qpcr and performed analysis for the ncrnas	grew bacteria, extracted rna, conducted qpcr and performed analysis for the ncrnas	Performed the experiments	Investigation	YES
5870498	29587634	REWH	2	supervised the project and edited the manuscript	supervised the project and edited the manuscript	Wrote the paper	Supervision|Writing - Review & Editing	YES
5870498	29587634	RL	2	assisted in growing the bacteria	assisted in growing the bacteria	-	-	NO
5870498	29587634	RS	2	conducted analysis on the transcription start sites	conducted analysis on the transcription start sites	Performed the experiments	Investigation	YES
5870498	29587634	SJHS	2	performed sequence alignments and compared data between libraries	performed sequence alignments and compared data between libraries	Performed the experiments	Investigation	YES
5365015	28348420	AOM	2	critical review to ensure robust intellectual content	critical review to ensure robust intellectual content	-	-	NO
5365015	28348420	AP	2	critical review to ensure robust intellectual content	critical review to ensure robust intellectual content	-	-	NO
5365015	28348420	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
5365015	28348420	FZ	2	critical review to ensure robust intellectual content	critical review to ensure robust intellectual content	-	-	NO
5365015	28348420	GP	2	study conception, participation in its presentation and coordination|data analysis and paper composition|contributed equally to the paper	study conception, participation in its presentation and coordination	Conceived and designed the experiments	Conceptualization|Project administration	YES
5365015	28348420	GP	2	study conception, participation in its presentation and coordination|data analysis and paper composition|contributed equally to the paper	data analysis and paper composition	Analyzed the data	Formal analysis	YES
5365015	28348420	GP	2	study conception, participation in its presentation and coordination|data analysis and paper composition|contributed equally to the paper	contributed equally to the paper	-	-	NO
5365015	28348420	MA	2	data analysis and paper composition	data analysis and paper composition	Analyzed the data	Formal analysis	YES
5365015	28348420	SC	2	study conception, participation in its presentation and coordination|data analysis and paper composition|contributed equally to the paper	study conception, participation in its presentation and coordination	Conceived and designed the experiments	Conceptualization|Project administration	YES
5365015	28348420	SC	2	study conception, participation in its presentation and coordination|data analysis and paper composition|contributed equally to the paper	data analysis and paper composition	Analyzed the data	Formal analysis	YES
5365015	28348420	SC	2	study conception, participation in its presentation and coordination|data analysis and paper composition|contributed equally to the paper	contributed equally to the paper	-	-	NO
5365015	28348420	SM	2	critical review to ensure robust intellectual content	critical review to ensure robust intellectual content	-	-	NO
4420266	25942425	BAM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4420266	25942425	BAM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4420266	25942425	BAM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4420266	25942425	BAM	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4420266	25942425	HGB	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4420266	25942425	HGB	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4420266	25942425	HGB	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4420266	25942425	HGB	PLoS5	Conceived and designed the experiments|Performed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4420266	25942425	KA	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4420266	25942425	LEB	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4420266	25942425	LEB	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4420266	25942425	LEB	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4420266	25942425	LNLJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4420266	25942425	LNLJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4420266	25942425	LNLJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4420266	25942425	LNLJ	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4420266	25942425	TRF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4420266	25942425	TRF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4420266	25942425	TRF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4420266	25942425	TRF	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6192940	30328527	AJM	2	helped with the planning of the project, the chromatography, the interpretation of the mass spectra, and the finalization of the manuscript	helped with the planning of the project, the chromatography, the interpretation of the mass spectra, and the finalization of the manuscript	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Review & Editing	YES
6192940	30328527	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6192940	30328527	GJ	2	performed most of the experiments, initiated the project, and wrote the first version of the manuscript	performed most of the experiments, initiated the project, and wrote the first version of the manuscript	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Investigation|Writing - Original Draft	YES
6192940	30328527	LG	2	performed and interpreted the mass spectra, helped with the chromatography, and the completion of the manuscript	performed and interpreted the mass spectra, helped with the chromatography, and the completion of the manuscript	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5861219	29593753	BS	2	contributed to the complementation experiment	contributed to the complementation experiment	Performed the experiments	Investigation	YES
5861219	29593753	BW	2	performed the complementation experiment|analyzed and discussed the data	performed the complementation experiment	Performed the experiments	Investigation	YES
5861219	29593753	BW	2	performed the complementation experiment|analyzed and discussed the data	analyzed and discussed the data	Analyzed the data	Formal analysis	YES
5861219	29593753	CS	2	performed co-expression network analysis and all bioinformatic analyses|analyzed and discussed the data|with contributions from all coauthors	performed co-expression network analysis and all bioinformatic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5861219	29593753	CS	2	performed co-expression network analysis and all bioinformatic analyses|analyzed and discussed the data|with contributions from all coauthors	analyzed and discussed the data	Analyzed the data	Formal analysis	YES
5861219	29593753	CS	2	performed co-expression network analysis and all bioinformatic analyses|analyzed and discussed the data|with contributions from all coauthors	with contributions from all coauthors	-	-	NO
5861219	29593753	HT	2	analyzed and discussed the data|with contributions from all coauthors	analyzed and discussed the data	Analyzed the data	Formal analysis	YES
5861219	29593753	HT	2	analyzed and discussed the data|with contributions from all coauthors	with contributions from all coauthors	-	-	NO
5861219	29593753	JF	2	analyzed and discussed the data	analyzed and discussed the data	Analyzed the data	Formal analysis	YES
5861219	29593753	ND	2	helped with the rna seq analysis	helped with the rna seq analysis	Performed the experiments	Investigation	YES
5861219	29593753	SJ-L	2	performed the phylogenetic analyses	performed the phylogenetic analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5861219	29593753	The authors	2	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest	Performed the experiments	Investigation	YES
3927958	24378569	BGG	2	performed the experiments and discussed the results	performed the experiments and discussed the results	Performed the experiments	Investigation	YES
3927958	24378569	ED	2	conceived and designed the study|wrote the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3927958	24378569	ED	2	conceived and designed the study|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3927958	24378569	FO	2	performed imaging analysis	performed imaging analysis	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
3927958	24378569	FST	2	performed the experiments and discussed the results	performed the experiments and discussed the results	Performed the experiments	Investigation	YES
3927958	24378569	GC	2	conceived and designed the study	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3927958	24378569	MC	2	performed the experiments and discussed the results	performed the experiments and discussed the results	Performed the experiments	Investigation	YES
3927958	24378569	MG	2	conceived and designed the study|performed the experiments and discussed the results|wrote the manuscript	conceived and designed the study	Conceived and designed the experiments	Conceptualization|Methodology	YES
3927958	24378569	MG	2	conceived and designed the study|performed the experiments and discussed the results|wrote the manuscript	performed the experiments and discussed the results	Performed the experiments	Investigation	YES
3927958	24378569	MG	2	conceived and designed the study|performed the experiments and discussed the results|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
3927958	24378569	MT	2	performed the experiments and discussed the results	performed the experiments and discussed the results	Performed the experiments	Investigation	YES
3927958	24378569	QM	2	performed the experiments and discussed the results	performed the experiments and discussed the results	Performed the experiments	Investigation	YES
3927958	24378569	RD	2	performed imaging analysis	performed imaging analysis	Performed the experiments|Analyzed the data	Investigation|Visualization	YES
3927958	24378569	SB	2	performed the experiments and discussed the results|wrote the manuscript	performed the experiments and discussed the results	Performed the experiments	Investigation	YES
3927958	24378569	SB	2	performed the experiments and discussed the results|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
4680048	26713318	Ana Pecina	2	contributed equally	contributed equally	-	-	NO
4680048	26713318	Raquel M. Fernandez	2	contributed equally	contributed equally	-	-	NO
6270953	25429568	All authors	PLoS52	contributed to this study, read and approved the final manuscript	contributed to this study, read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6270953	25429568	DDX	PLoS52	performed the experiments and analyzed the data	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270953	25429568	DYH	PLoS52	conceived and designed the experiments|analyzed the data and wrote the paper	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
6270953	25429568	DYH	PLoS52	conceived and designed the experiments|analyzed the data and wrote the paper	analyzed the data and wrote the paper	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6270953	25429568	JW	PLoS52	revised the paper	revised the paper	Wrote the paper	Writing - Review & Editing	YES
6270953	25429568	YD	PLoS52	tested all the ee values of the compounds	tested all the ee values of the compounds	Performed the experiments	Investigation	YES
6270953	25429568	YX	PLoS52	performed the experiments and analyzed the data|tested all the ee values of the compounds	performed the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6270953	25429568	YX	PLoS52	performed the experiments and analyzed the data|tested all the ee values of the compounds	tested all the ee values of the compounds	Performed the experiments	Investigation	YES
2048666	18000535	AH	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
2048666	18000535	AH	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2048666	18000535	BE	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
2048666	18000535	BE	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2048666	18000535	HH	PLoS5	Conceived and designed the experiments|Provided the final corrections	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2048666	18000535	HH	PLoS5	Conceived and designed the experiments|Provided the final corrections	Provided the final corrections	-	-	NO
2048666	18000535	KL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2048666	18000535	KL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2048666	18000535	KL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2048666	18000535	KL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2048666	18000535	ML	PLoS5	Performed the experiments|Analyzed the data|Corrected paper	Performed the experiments	Performed the experiments	Investigation	YES
2048666	18000535	ML	PLoS5	Performed the experiments|Analyzed the data|Corrected paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2048666	18000535	ML	PLoS5	Performed the experiments|Analyzed the data|Corrected paper	Corrected paper	Wrote the paper	Writing - Review & Editing	YES
2048666	18000535	MR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2048666	18000535	MR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2048666	18000535	MR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2048666	18000535	MR	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2048666	18000535	PL	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
2048666	18000535	PL	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
2048666	18000535	RZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Provided the final corrections	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2048666	18000535	RZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Provided the final corrections	Analyzed the data	Analyzed the data	Formal analysis	YES
2048666	18000535	RZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Provided the final corrections	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2048666	18000535	RZ	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper|Provided the final corrections	Provided the final corrections	-	-	NO
5870499	29580205	BJL	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5870499	29580205	CMF	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5870499	29580205	EFM	PLoS5	Conceived and designed the experiments|Performed the study and analyzed the data	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5870499	29580205	EFM	PLoS5	Conceived and designed the experiments|Performed the study and analyzed the data	Performed the study and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5870499	29580205	LD	PLoS5	Performed the study and analyzed the data	Performed the study and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5870499	29580205	SA	PLoS5	Performed the study and analyzed the data	Performed the study and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5870499	29580205	SES	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5870499	29580205	SRC	PLoS5	Conceived and designed the experiments|Performed the study and analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5870499	29580205	SRC	PLoS5	Conceived and designed the experiments|Performed the study and analyzed the data|Wrote the paper	Performed the study and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5870499	29580205	SRC	PLoS5	Conceived and designed the experiments|Performed the study and analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
5870499	29580205	WGQ	PLoS5	Conceived and designed the experiments|Performed the study and analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5870499	29580205	WGQ	PLoS5	Conceived and designed the experiments|Performed the study and analyzed the data|Wrote the paper	Performed the study and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5870499	29580205	WGQ	PLoS5	Conceived and designed the experiments|Performed the study and analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6069820	30083346	All authors	2	participated in the patient care	participated in the patient care	Performed the experiments	Investigation	YES
6069820	30083346	NA	2	were a major contributor in writing the manuscript	were a major contributor in writing the manuscript	Wrote the paper	Writing - Original Draft	YES
6069820	30083346	SK	2	were a major contributor in writing the manuscript	were a major contributor in writing the manuscript	Wrote the paper	Writing - Original Draft	YES
4420267	25941810	CEM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4420267	25941810	CEM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4420267	25941810	CEM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4420267	25941810	JDR	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4420267	25941810	JDR	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4420267	25941810	JDR	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4420267	25941810	JTL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4420267	25941810	JTL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4420267	25941810	JTL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4420267	25941810	JTL	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
6192943	30334115	AAE	2	have collaborated on design of study, data collection and manuscript preparation and revision	have collaborated on design of study, data collection and manuscript preparation and revision	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
6192943	30334115	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6192943	30334115	HE	2	have collaborated on design of study, data collection and manuscript preparation and revision	have collaborated on design of study, data collection and manuscript preparation and revision	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
6192943	30334115	MHS	2	have collaborated on technical analysis of data and manuscript revision	have collaborated on technical analysis of data and manuscript revision	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
6192943	30334115	MM	2	have collaborated on technical analysis of data and manuscript revision	have collaborated on technical analysis of data and manuscript revision	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
6192943	30334115	MP	2	performed the economic evaluation of data	performed the economic evaluation of data	Performed the experiments	Investigation	YES
6192943	30334115	MTG	2	have collaborated on technical analysis of data and manuscript revision	have collaborated on technical analysis of data and manuscript revision	Analyzed the data|Wrote the paper	Formal analysis|Writing - Review & Editing	YES
6192943	30334115	TZM	2	have collaborated on design of study, data collection and manuscript preparation and revision	have collaborated on design of study, data collection and manuscript preparation and revision	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Investigation|Methodology|Writing - Original Draft|Writing - Review & Editing	YES
6192943	30334115	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
6030579	29967303	Both authors	2	gave final approval for publication	gave final approval for publication	-	-	NO
4420268	25942444	DG	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4420268	25942444	EDJ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4420268	25942444	LFB	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4420268	25942444	LFB	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4420268	25942444	MP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4420268	25942444	MP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4420268	25942444	MP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4420268	25942444	MP	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4420268	25942444	NZ	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4420268	25942444	PV	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4420268	25942444	SH	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4420268	25942444	SH	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4420268	25942444	SLD	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4420268	25942444	SLD	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4420268	25942444	SLD	PLoS5	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4420268	25942444	YM	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2048740	17987129	AS	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2048740	17987129	HW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2048740	17987129	HW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2048740	17987129	HW	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2048740	17987129	HY	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2048740	17987129	JL	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2048740	17987129	MA	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
2048740	17987129	WL	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
2048740	17987129	WL	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
6270954	24776813	A. Debbab	2	is part of the grant that supported this work	is part of the grant that supported this work	-	-	NO
6270954	24776813	D. Lai	2	elucidated the structures of the compounds	elucidated the structures of the compounds	Performed the experiments	Investigation	YES
6270954	24776813	F.B.C.	2	contributed in the confirming of isolation procedures, especially interpretation of the spectra and also part of the preparation of the manuscript	contributed in the confirming of isolation procedures, especially interpretation of the spectra and also part of the preparation of the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6270954	24776813	J. Nwodo	2	is the principal investigator, did the isolation, identification and prepared the manuscript, hence the corresponding author	is the principal investigator, did the isolation, identification and prepared the manuscript, hence the corresponding author	Conceived and designed the experiments|Performed the experiments|Wrote the paper	Conceptualization|Funding acquisition|Investigation|Writing - Original Draft	YES
6270954	24776813	P. Proksch	2	made available the laboratory, including equipments, consumables and guided the processes of isolation of these compounds	made available the laboratory, including equipments, consumables and guided the processes of isolation of these compounds	Performed the experiments	Investigation|Supervision	YES
6270954	24776813	R. Brun	2	carried out the bioassay and contributed in the preparing of the manuscript	carried out the bioassay and contributed in the preparing of the manuscript	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
5861524	29593750	CC	7	contributed to conception and design of the study and statistical analyses, participated substantially in the interpretation of the results and drafting of the manuscript, and approved the final version to be published	contributed to conception and design of the study and statistical analyses, participated substantially in the interpretation of the results and drafting of the manuscript, and approved the final version to be published	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
5861524	29593750	HP	7	contributed to conception and design of the study, was responsible for field collections and laboratory analyses, conducted the statistical analyses, contributed to the interpretation of the results, wrote the first version of the manuscript, and approved the final version to be published	contributed to conception and design of the study, was responsible for field collections and laboratory analyses, conducted the statistical analyses, contributed to the interpretation of the results, wrote the first version of the manuscript, and approved the final version to be published	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
5861524	29593750	JS	7	contributed to conception and design of the study, participated substantially in the statistical analyses, interpretation of the results, and drafting of the manuscript, and approved the final version to be published	contributed to conception and design of the study, participated substantially in the statistical analyses, interpretation of the results, and drafting of the manuscript, and approved the final version to be published	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceptualization|Formal analysis|Methodology|Writing - Original Draft	YES
4820790	26974011	B.R.	2	contributed equally	contributed equally	-	-	NO
4820790	26974011	C.O.	2	contributed equally	contributed equally	-	-	NO
4820790	26974011	SS	2	contributed equally	contributed equally	-	-	NO
6069862	30083347	GS	2	contributed to the data collection, data analysis confirmation, and manuscript proofreading	contributed to the data collection, data analysis confirmation, and manuscript proofreading	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6069862	30083347	HS	2	contributed to the data collection, data analysis confirmation, and manuscript preparation	contributed to the data collection, data analysis confirmation, and manuscript preparation	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6069862	30083347	KK	2	contributed to the data collection, manuscript preparation, and chart creation	contributed to the data collection, manuscript preparation, and chart creation	Performed the experiments|Wrote the paper	Investigation|Writing - Original Draft	YES
6069862	30083347	SB	2	contributed to the data collection, data analysis confirmation, and chart creation	contributed to the data collection, data analysis confirmation, and chart creation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6069862	30083347	TA	2	contributed to the data collection, data analysis confirmation, and chart creation	contributed to the data collection, data analysis confirmation, and chart creation	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6069862	30083347	TH	2	contributed to the research plan creation, data collection, data analysis confirmation, and manuscript proofreading	contributed to the research plan creation, data collection, data analysis confirmation, and manuscript proofreading	Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools	Formal analysis|Investigation|Resources	YES
6069862	30083347	TY	2	contributed to the data collection, data analysis confirmation, and manuscript proofreading	contributed to the data collection, data analysis confirmation, and manuscript proofreading	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6069862	30083347	YO	2	contributed to the study conception, research plan creation, data collection, data analysis, and manuscript preparation	contributed to the study conception, research plan creation, data collection, data analysis, and manuscript preparation	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceptualization|Formal analysis|Investigation|Resources|Writing - Original Draft	YES
3927959	24375627	AF	PLoS52	conceived and designed the study and wrote the manuscript|supervised whole study	conceived and designed the study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
3927959	24375627	AF	PLoS52	conceived and designed the study and wrote the manuscript|supervised whole study	supervised whole study	-	Supervision	YES
3927959	24375627	AL	PLoS52	performed the experiments|analyzed data	performed the experiments	Performed the experiments	Investigation	YES
3927959	24375627	AL	PLoS52	performed the experiments|analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
3927959	24375627	FAS	PLoS52	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
3927959	24375627	FB	PLoS52	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
3927959	24375627	IG	PLoS52	performed the experiments|analyzed data	performed the experiments	Performed the experiments	Investigation	YES
3927959	24375627	IG	PLoS52	performed the experiments|analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
3927959	24375627	MFP	PLoS52	analyzed data	analyzed data	Analyzed the data	Formal analysis	YES
3927959	24375627	MG	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
3927959	24375627	MRS	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
3927959	24375627	SD	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
3927959	24375627	SEA	PLoS52	conceived and designed the study and wrote the manuscript|supervised whole study	conceived and designed the study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
3927959	24375627	SEA	PLoS52	conceived and designed the study and wrote the manuscript|supervised whole study	supervised whole study	-	Supervision	YES
3927959	24375627	SG	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
3927959	24375627	YH	PLoS52	performed the majority of the experiments and analyzed the data|conceived and designed the study and wrote the manuscript	performed the majority of the experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3927959	24375627	YH	PLoS52	performed the majority of the experiments and analyzed the data|conceived and designed the study and wrote the manuscript	conceived and designed the study and wrote the manuscript	Conceived and designed the experiments|Wrote the paper	Conceptualization|Methodology|Writing - Original Draft	YES
6192944	30334113	AA	2	has contribution in conducting few experiments	has contribution in conducting few experiments	Performed the experiments	Investigation	YES
6192944	30334113	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6192944	30334113	BK	2	has equal contribution on conducting experiments, analysing the results, and writing the paper	has equal contribution on conducting experiments, analysing the results, and writing the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6192944	30334113	KA	2	has contributed in writing the paper	has contributed in writing the paper	Wrote the paper	Writing - Original Draft	YES
6192944	30334113	NB	2	has equal contribution on conducting experiments, analysing the results, and writing the paper	has equal contribution on conducting experiments, analysing the results, and writing the paper	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
6192944	30334113	PV	2	has contribution in designing the experiments, analysing the results and writing the manuscripts	has contribution in designing the experiments, analysing the results and writing the manuscripts	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Methodology|Writing - Original Draft	YES
4420270	25942636	BCPF	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4420270	25942636	CSP	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4420270	25942636	LAA	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4420270	25942636	NDR	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4420270	25942636	NRGA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4420270	25942636	NRGA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
4420270	25942636	NRGA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4420270	25942636	NRGA	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4420270	25942636	SBM	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4420270	25942636	SBM	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
4420270	25942636	SCO	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4420270	25942636	SCO	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4420270	25942636	SCO	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4420270	25942636	SCO	PLoS5	Conceived and designed the experiments|Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4420270	25942636	VPM	PLoS5	Performed the experiments|Analyzed the data	Performed the experiments	Performed the experiments	Investigation	YES
4420270	25942636	VPM	PLoS5	Performed the experiments|Analyzed the data	Analyzed the data	Analyzed the data	Formal analysis	YES
5381531	28076934	CY	2	data acquisition and analysis	data acquisition and analysis	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5381531	28076934	JC	2	study design revision	study design revision	Conceived and designed the experiments|Wrote the paper	Methodology|Writing - Review & Editing	YES
5381531	28076934	YC	2	important contributions to the manuscript, final approval of the version to be published	important contributions to the manuscript, final approval of the version to be published	-	-	NO
5381531	28076934	YD	2	study design	study design	Conceived and designed the experiments	Methodology	YES
5381531	28076934	ZQ	2	critical manuscript revision for important intellectual content	critical manuscript revision for important intellectual content	Wrote the paper	Writing - Review & Editing	YES
5381531	28076934	ZW	2	manuscript drafting and final approval	manuscript drafting and final approval	Wrote the paper	Writing - Original Draft	YES
6270955	24936708	C.W.	2	participated in designing the study|analyzed the data and wrote the manuscript	participated in designing the study	Conceived and designed the experiments	Methodology	YES
6270955	24936708	C.W.	2	participated in designing the study|analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6270955	24936708	H.S.	2	performed the experiments and collected the data	performed the experiments and collected the data	Performed the experiments	Investigation	YES
6270955	24936708	J.L.	2	analyzed the data and wrote the manuscript	analyzed the data and wrote the manuscript	Analyzed the data|Wrote the paper	Formal analysis|Writing - Original Draft	YES
6270955	24936708	Q.Z.	2	directed the study	directed the study	-	Supervision	YES
2048753	18000539	LM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2048753	18000539	LM	PLoS5	Conceived and designed the experiments|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2048753	18000539	MM	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2048753	18000539	MM	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2048753	18000539	NM	PLoS5	Conceived and designed the experiments	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2048753	18000539	SC	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2048753	18000539	SC	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2048753	18000539	SP	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2048753	18000539	SP	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2048753	18000539	TA	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2048753	18000539	TA	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4854195	26828317	C.B.K.	2	contributed equally	contributed equally	-	-	NO
4854195	26828317	N.R.P.	2	contributed equally	contributed equally	-	-	NO
6081801	30094030	KN	2	substantially contributed to the manuscript and protocols	substantially contributed to the manuscript and protocols	Conceived and designed the experiments	Methodology	YES
6081801	30094030	YF	2	substantially contributed to the manuscript and protocols	substantially contributed to the manuscript and protocols	Conceived and designed the experiments	Methodology	YES
6081801	30094030	YN	2	is the guarantor of the manuscript content and protocols	is the guarantor of the manuscript content and protocols	Conceived and designed the experiments	Methodology	YES
5861560	29593774	CZ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5861560	29593774	DJ	PLoS52	conceived and designed the experiments|wrote the article with	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5861560	29593774	DJ	PLoS52	conceived and designed the experiments|wrote the article with	wrote the article with	Wrote the paper	Writing - Original Draft	YES
5861560	29593774	JC	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5861560	29593774	MH	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5861560	29593774	QZ	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5861560	29593774	TD	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5861560	29593774	TS	PLoS52	conceived and designed the experiments|performed the experiments|wrote the article with	conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
5861560	29593774	TS	PLoS52	conceived and designed the experiments|performed the experiments|wrote the article with	performed the experiments	Performed the experiments	Investigation	YES
5861560	29593774	TS	PLoS52	conceived and designed the experiments|performed the experiments|wrote the article with	wrote the article with	Wrote the paper	Writing - Original Draft	YES
5861560	29593774	XW	PLoS52	performed the experiments	performed the experiments	Performed the experiments	Investigation	YES
5861560	29593774	all the authors	PLoS52	contributed with the wrote the article with	contributed with the wrote the article with	Wrote the paper	Writing - Original Draft	YES
4420271	25942446	JL	PLoS5	Conceived and designed the experiments|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4420271	25942446	JL	PLoS5	Conceived and designed the experiments|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4420271	25942446	LML	PLoS5	Conceived and designed the experiments|Contributed to the interpretation of the results and reviewed	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
4420271	25942446	LML	PLoS5	Conceived and designed the experiments|Contributed to the interpretation of the results and reviewed	Contributed to the interpretation of the results and reviewed	Analyzed the data	Formal analysis	YES
4420271	25942446	MS	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4420271	25942446	MYF	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
4420271	25942446	MYF	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
4420271	25942446	MYF	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
4420271	25942446	QML	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4420271	25942446	YJR	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
4420271	25942446	YYT	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
5870820	29587633	BMR	1	Conceived and designed research|Conducted analyses|Writing the manuscript	Conceived and designed research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5870820	29587633	BMR	1	Conceived and designed research|Conducted analyses|Writing the manuscript	Conducted analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5870820	29587633	BMR	1	Conceived and designed research|Conducted analyses|Writing the manuscript	Writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5870820	29587633	DTS	1	Conceived and designed research|Writing the manuscript	Conceived and designed research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5870820	29587633	DTS	1	Conceived and designed research|Writing the manuscript	Writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5870820	29587633	EEC	1	Conceived and designed research|Conducted laboratory work|Conducted analyses|Writing the manuscript	Conceived and designed research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5870820	29587633	EEC	1	Conceived and designed research|Conducted laboratory work|Conducted analyses|Writing the manuscript	Conducted laboratory work	Performed the experiments	Investigation	YES
5870820	29587633	EEC	1	Conceived and designed research|Conducted laboratory work|Conducted analyses|Writing the manuscript	Conducted analyses	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5870820	29587633	EEC	1	Conceived and designed research|Conducted laboratory work|Conducted analyses|Writing the manuscript	Writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5870820	29587633	GB	1	Contributed samples and council on the study species	Contributed samples and council on the study species	Contributed reagents/materials/analysis tools	Resources	YES
5870820	29587633	SB	1	Conceived and designed research|Writing the manuscript	Conceived and designed research	Conceived and designed the experiments	Conceptualization|Methodology	YES
5870820	29587633	SB	1	Conceived and designed research|Writing the manuscript	Writing the manuscript	Wrote the paper	Writing - Original Draft	YES
5870820	29587633	SV	1	Conducted laboratory work	Conducted laboratory work	Performed the experiments	Investigation	YES
6199207	30353255	All	2	data analyzed during this study are included in this manuscript and additional material	data analyzed during this study are included in this manuscript and additional material	Analyzed the data	Formal analysis	YES
6199207	30353255	All authors	2	read and approved the final manuscript	read and approved the final manuscript	Wrote the paper	Writing - Review & Editing	YES
6199207	30353255	HPD	2	designed the study|wrote the manuscript|funded this study	designed the study	Conceived and designed the experiments	Methodology	YES
6199207	30353255	HPD	2	designed the study|wrote the manuscript|funded this study	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6199207	30353255	HPD	2	designed the study|wrote the manuscript|funded this study	funded this study	-	Funding acquisition	YES
6199207	30353255	LJO	2	designed the study|funded this study	designed the study	Conceived and designed the experiments	Methodology	YES
6199207	30353255	LJO	2	designed the study|funded this study	funded this study	-	Funding acquisition	YES
6199207	30353255	TBH	2	designed the study|carried out experiments and analyzed the data|wrote the manuscript	designed the study	Conceived and designed the experiments	Methodology	YES
6199207	30353255	TBH	2	designed the study|carried out experiments and analyzed the data|wrote the manuscript	carried out experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6199207	30353255	TBH	2	designed the study|carried out experiments and analyzed the data|wrote the manuscript	wrote the manuscript	Wrote the paper	Writing - Original Draft	YES
6199207	30353255	TJ	2	carried out experiments and analyzed the data	carried out experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6199207	30353255	The authors	2	declare that they have no competing interests	declare that they have no competing interests	-	-	NO
6199207	30353255	XH	2	carried out experiments and analyzed the data	carried out experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6199207	30353255	YFY	2	carried out experiments and analyzed the data	carried out experiments and analyzed the data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
6053982	30012744	All authors	2	gave final approval for publication	gave final approval for publication	-	-	NO
6053982	30012744	K.F.H.	2	conceived the article|revised it	conceived the article	Conceived and designed the experiments	Conceptualization	YES
6053982	30012744	K.F.H.	2	conceived the article|revised it	revised it	Wrote the paper	Writing - Review & Editing	YES
6053982	30012744	Q.S.	2	conceived the article	conceived the article	Conceived and designed the experiments	Conceptualization	YES
6053982	30012744	X.Z.	2	conceived the article|revised it	conceived the article	Conceived and designed the experiments	Conceptualization	YES
6053982	30012744	X.Z.	2	conceived the article|revised it	revised it	Wrote the paper	Writing - Review & Editing	YES
2048754	18000534	DM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2048754	18000534	DM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2048754	18000534	DM	PLoS5	Conceived and designed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2048754	18000534	LW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Conceived and designed the experiments	Conceived and designed the experiments	Conceptualization|Methodology	YES
2048754	18000534	LW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Performed the experiments	Performed the experiments	Investigation	YES
2048754	18000534	LW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Analyzed the data	Analyzed the data	Formal analysis	YES
2048754	18000534	LW	PLoS5	Conceived and designed the experiments|Performed the experiments|Analyzed the data|Wrote the paper	Wrote the paper	Wrote the paper	Writing - Original Draft	YES
2048754	18000534	RK	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2048754	18000534	SD	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
2048754	18000534	SE	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Analyzed the data	Analyzed the data	Formal analysis	YES
2048754	18000534	SE	PLoS5	Analyzed the data|Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
2048754	18000534	TK	PLoS5	Performed the experiments	Performed the experiments	Performed the experiments	Investigation	YES
2048754	18000534	XX	PLoS5	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Contributed reagents/materials/analysis tools	Resources	YES
6083584	30116532	AI	2	managed data, including quality control	managed data, including quality control	Performed the experiments|Analyzed the data	Data curation|Validation	YES
6083584	30116532	FT	2	was a major contributor in writing the manuscript	was a major contributor in writing the manuscript	Wrote the paper	Writing - Original Draft	YES
6083584	30116532	HO	2	analyzed and interpreted patient data	analyzed and interpreted patient data	Analyzed the data	Formal analysis	YES
6083584	30116532	TI	2	supervised the conduct of the trial and data collection	supervised the conduct of the trial and data collection	Performed the experiments	Investigation|Supervision	YES
6083584	30116532	YW	2	managed data, including quality control	managed data, including quality control	Performed the experiments|Analyzed the data	Data curation|Validation	YES
3927960	24375628	CC	4	the analysis and interpretation of data was performed by	the analysis and interpretation of data was performed by	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3927960	24375628	DL	4	the analysis and interpretation of data was performed by	the analysis and interpretation of data was performed by	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3927960	24375628	GES	4	Study was conceived by|experiments were designed by|the analysis and interpretation of data was performed by|the final manuscript was prepared by|the whole study was supervised by	Study was conceived by	Conceived and designed the experiments	Conceptualization	YES
3927960	24375628	GES	4	Study was conceived by|experiments were designed by|the analysis and interpretation of data was performed by|the final manuscript was prepared by|the whole study was supervised by	experiments were designed by	Conceived and designed the experiments	Methodology	YES
3927960	24375628	GES	4	Study was conceived by|experiments were designed by|the analysis and interpretation of data was performed by|the final manuscript was prepared by|the whole study was supervised by	the analysis and interpretation of data was performed by	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3927960	24375628	GES	4	Study was conceived by|experiments were designed by|the analysis and interpretation of data was performed by|the final manuscript was prepared by|the whole study was supervised by	the final manuscript was prepared by	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3927960	24375628	GES	4	Study was conceived by|experiments were designed by|the analysis and interpretation of data was performed by|the final manuscript was prepared by|the whole study was supervised by	the whole study was supervised by	-	Supervision	YES
3927960	24375628	IG	4	the analysis and interpretation of data was performed by|the final manuscript was prepared by	the analysis and interpretation of data was performed by	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3927960	24375628	IG	4	the analysis and interpretation of data was performed by|the final manuscript was prepared by	the final manuscript was prepared by	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3927960	24375628	JWB	4	experiments were designed by|the analysis and interpretation of data was performed by|the final manuscript was prepared by	experiments were designed by	Conceived and designed the experiments	Methodology	YES
3927960	24375628	JWB	4	experiments were designed by|the analysis and interpretation of data was performed by|the final manuscript was prepared by	the analysis and interpretation of data was performed by	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3927960	24375628	JWB	4	experiments were designed by|the analysis and interpretation of data was performed by|the final manuscript was prepared by	the final manuscript was prepared by	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3927960	24375628	MJD	4	the analysis and interpretation of data was performed by|the final manuscript was prepared by	the analysis and interpretation of data was performed by	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3927960	24375628	MJD	4	the analysis and interpretation of data was performed by|the final manuscript was prepared by	the final manuscript was prepared by	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3927960	24375628	MP	4	experiments were designed by|the analysis and interpretation of data was performed by|the final manuscript was prepared by|the final manuscript was prepared by	experiments were designed by	Conceived and designed the experiments	Methodology	YES
3927960	24375628	MP	4	experiments were designed by|the analysis and interpretation of data was performed by|the final manuscript was prepared by|the final manuscript was prepared by	the analysis and interpretation of data was performed by	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3927960	24375628	MP	4	experiments were designed by|the analysis and interpretation of data was performed by|the final manuscript was prepared by|the final manuscript was prepared by	the final manuscript was prepared by	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3927960	24375628	MP	4	experiments were designed by|the analysis and interpretation of data was performed by|the final manuscript was prepared by|the final manuscript was prepared by	the final manuscript was prepared by	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3927960	24375628	MR	4	Study was conceived by|experiments were designed by|the analysis and interpretation of data was performed by|the final manuscript was prepared by	Study was conceived by	Conceived and designed the experiments	Conceptualization	YES
3927960	24375628	MR	4	Study was conceived by|experiments were designed by|the analysis and interpretation of data was performed by|the final manuscript was prepared by	experiments were designed by	Conceived and designed the experiments	Methodology	YES
3927960	24375628	MR	4	Study was conceived by|experiments were designed by|the analysis and interpretation of data was performed by|the final manuscript was prepared by	the analysis and interpretation of data was performed by	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3927960	24375628	MR	4	Study was conceived by|experiments were designed by|the analysis and interpretation of data was performed by|the final manuscript was prepared by	the final manuscript was prepared by	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3927960	24375628	NDM	4	Study was conceived by|experiments were designed by|the analysis and interpretation of data was performed by|the final manuscript was prepared by	Study was conceived by	Conceived and designed the experiments	Conceptualization	YES
3927960	24375628	NDM	4	Study was conceived by|experiments were designed by|the analysis and interpretation of data was performed by|the final manuscript was prepared by	experiments were designed by	Conceived and designed the experiments	Methodology	YES
3927960	24375628	NDM	4	Study was conceived by|experiments were designed by|the analysis and interpretation of data was performed by|the final manuscript was prepared by	the analysis and interpretation of data was performed by	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3927960	24375628	NDM	4	Study was conceived by|experiments were designed by|the analysis and interpretation of data was performed by|the final manuscript was prepared by	the final manuscript was prepared by	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3927960	24375628	PMMcG	4	experiments were designed by|the analysis and interpretation of data was performed by|the final manuscript was prepared by	experiments were designed by	Conceived and designed the experiments	Methodology	YES
3927960	24375628	PMMcG	4	experiments were designed by|the analysis and interpretation of data was performed by|the final manuscript was prepared by	the analysis and interpretation of data was performed by	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3927960	24375628	PMMcG	4	experiments were designed by|the analysis and interpretation of data was performed by|the final manuscript was prepared by	the final manuscript was prepared by	Wrote the paper	Writing - Original Draft|Writing - Review & Editing	YES
3927960	24375628	SB-N	4	the analysis and interpretation of data was performed by	the analysis and interpretation of data was performed by	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
3927960	24375628	SBM	4	experiments were designed by	experiments were designed by	Conceived and designed the experiments	Methodology	YES
3927960	24375628	SS	4	the analysis and interpretation of data was performed by	the analysis and interpretation of data was performed by	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
4681007	26759811	Aijaz Khan	2	were responsible for the animal care, treatment, and the sample collection|analysed the results of the experiments	were responsible for the animal care, treatment, and the sample collection	Performed the experiments	Investigation	YES
4681007	26759811	Aijaz Khan	2	were responsible for the animal care, treatment, and the sample collection|analysed the results of the experiments	analysed the results of the experiments	Analyzed the data	Formal analysis	YES
4681007	26759811	Ibrahim Alhazza	2	analysed the results of the experiments	analysed the results of the experiments	Analyzed the data	Formal analysis	YES
4681007	26759811	Iftekhar Hassan	2	analysed the results of the experiments	analysed the results of the experiments	Analyzed the data	Formal analysis	YES
4681007	26759811	Imrana Naseem	2	analysed the results of the experiments	analysed the results of the experiments	Analyzed the data	Formal analysis	YES
4681007	26759811	Maria Salman	2	were responsible for the animal care, treatment, and the sample collection	were responsible for the animal care, treatment, and the sample collection	Performed the experiments	Investigation	YES
5861628	29593752	AC	7	Edited the manuscript|Obtained funding for the project	Edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5861628	29593752	AC	7	Edited the manuscript|Obtained funding for the project	Obtained funding for the project	-	Funding acquisition	YES
5861628	29593752	CM	7	Edited the manuscript|Obtained funding for the project	Edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5861628	29593752	CM	7	Edited the manuscript|Obtained funding for the project	Obtained funding for the project	-	Funding acquisition	YES
5861628	29593752	JG	7	Analyzed the phenotypic and genotypic data and drafted the manuscript	Analyzed the phenotypic and genotypic data and drafted the manuscript	Performed the experiments|Analyzed the data|Wrote the paper	Formal analysis|Investigation|Writing - Original Draft	YES
5861628	29593752	KG-C	7	Edited the manuscript	Edited the manuscript	Wrote the paper	Writing - Review & Editing	YES
5861628	29593752	KJ	7	Analyzed the phenotypic data	Analyzed the phenotypic data	Performed the experiments|Analyzed the data	Formal analysis|Investigation	YES
5861628	29593752	MH	7	P